Figure S2 >Case 1 aroE Consensus GGCCAGCCTGACCCGCCCGCAGGGGACGAGTCCGCTCGTCCCGTCCCACTCCGGCAAAGG AACGACCCATGGACCGCTATTGCGTATTCGGCAACCCCATCGGCCACAGCAAGTCGCCGC TGATCCACCGCCTGTTCGCCGAGCAGACCGGCGAGGCGCTGGTCTATGACGCGCAACTGG CGCCGCTGGACGATTTCCCCGGGTTCGCCCGGCGCTTCTTCGAGCAGGGCAAGGGCGCCA ATGTCACCGTGCCGTTCAAGGAAGAGGCCTATCGTCTGGTGGACGAGTTGAGCGAGCGGG CCACCCGGGCCGGGGCGGTGAACACCCTGATCCGCCTCGCCGACGGTCGCCTGCGCGGCG ACAACACCGACGGCGCCGGCCTGCTGCGGGACCTGACGGCGAACGCCGGGGTCGAGCTGC GCGGCAAGCGGGTTCTCCTGCTCGGCGCCGGCGGTGCGGTGCGTGGGGTGCTCGAACCCT TCCTCGGCGAGTGCCCGGCGGAGTTGCTGATCGCCAACCGCACGGCGCGGAAGGCCGTGG ACCTGGCCGAGCGGTTCGCCGACCTCGGCGCGGTGCACGGCTGCGGTTTCGCCGAGGTCG AAGGGCCTTTCGACCTGATCGTCAACGGCACCTCGGCCAGTCTTGCCGGCGACGTGCCGC CGCTGGCGCAGAGCGTGATCGAGCCCGGCCGTACCGTCTGCTACGACATGATGTATGCCA AGGAACCGACTGCCTTCAACCGCTGGGCCGCCGAACGCGGTGCGGCGCGTACCCTGGATG GCCTGGGCATGCTGGTGGAGCAGGCCGCCGAGGCATTCTTCCTCTGGCGCGGCGTGCGTC CTGCCTCGGCGCCAGTGTTGGAGACGCTGCGCCGACAGTTGGCAACTGTCTGAGTTGTCA GGCGGCATTTGAGAC >Case 2 aroE Consensus GTGATTCCTACATGTCAGATGGAAGCCAATTTGAGACGTACGTCTCAAATGCCGCCTGAC AACTCAGACAGTTGCCAACTGTCGGCGCAGCGTCTCCAACACTGGCGCCGAGGCAGGACG CACGCCGCGCCAGAGGAAGAATGCCTCGGCGGCCTGCTCCACCAGCATGCCCAGGCCATC CAGGGTACGCGCCGCACCGCGTTCGGCGGCCCAGCGGTTGAAGGCAGTCGGTTCCTTGGC ATACATCATGTCGTAGCAGACGGTACGGCCGGGCTCGATCACGCTCTGCGCCAGCGGCGG CACGTCGCCGGCAAGACTGGCCGAGGTGCCGTTGACGATCAGGTCGAAAGGCCCTTCGAC CTCGGCGAAACCGCAGCCGTGCACCGCGCCGAGGTCGGCGAACCGCTCGGCCAGGTCCAC GGCCTTCCGCGCCGTGCGGTTGGCGATCAGCAACTCCGCCGGGCACTCGCCGAGGAAGGG TTCGAGCACCCCACGCACCGCACCGCCGGCGCCGAGCAGGAGAACCCGCTTGCCGCGCAG CTCGACCCCGGCGTTCGCCGTCAGGTCCCGCAGCAGGCCGGCGCCGTCGGTGTTGTCGCC GCGCAGGCGACCGTCGGCGAGGCGGATCAGGGTGTTCACCGCCCCGGCCCGGGTGGCCCG CTCGCTCAACTCGTCCACCAGACGATAGGCCTCTTCCTTGAACGGCACGGTGACATTGGC GCCCTTGCCCTGCTCGAAGAAGCGCCGGGCGAACCCGGGGAAATCGTCCAGCGGCGCCAG TTGCGCGTCATAGACCAGCGCCTCGCCGGTCTGCTCGGCGAACAGGCGGTGGATCAGCGG CGACTTGCTGTGGCCGATGGGGTTGCCGAATACGCAATAGCGGTCCATGGGTCGTTCCTT TGCCGGAGTGGACGGGACGAGCGGACTCGTCCCCTGCGGGCGGGTCAGGGCTGGCCGGCG AGCCAATCGCGGTCGGCGAGGAAATACTCGGTCAGGCGCGCTTCCTCGCTGCCCGGCTCG GGTTTCCAG >Case 4 aroE Consensus TACATGTCAGATGGAAGCCAATTTGAGACGTACGTCTCAAATGCCGCCTGACAACTCAGA CAGTTGCCAACTGTCGGCGCAGCGTCTCCAACACTGGCGCCGAGGCAGGACGCACGCCGC GCCAGAGGAAGAATGCCTCGGCGGCCTGCTCCACCAGCATGCCCAGGCCATCCAGGGTAC GCGCCGCACCGCGTTCGGCGGCCCAGCGGTTGAAGGCAGTCGGTTCCTTGGCATACATCA TGTCGTAGCAGACGGTACGGCCGGGCTCGATCACGCTCTGCGCCAGCGGCGGCACGTCGC CGGCAAGACTGGCCGAGGTGCCGTTGACGATCAGGTCGAAAGGCCCTTCGACCTCGGCGA AACCGCAGCCGTGCACCGCGCCGAGGTCGGCGAACCGCTCGGCCAGGTCCACGGCCTTCC GCGCCGTGCGGTTGGCGATCAGCAACTCCGCCGGGCACTCGCCGAGGAAGGGTTCGAGCA CCCCACGCACCGCACCGCCGGCGCCGAGCAGGAGAACCCGCTTGCCGCGCAGCTCGACCC CGGCGTTCGCCGTCAGGTCCCGCAGCAGGCCGGCGCCGTCGGTGTTGTCGCCGCGCAGGC GACCGTCGGCGAGGCGGATCAGGGTGTTCACCGCCCCGGCCCGGGTGGCCCGCTCGCTCA ACTCGTCCACCAGACGATAGGCCTCTTCCTTGAACGGCACGGTGACATTGGCGCCCTTGC CCTGCTCGAAGAAGCGCCGGGCGAACCCGGGGAAATCGTCCAGCGGCGCCAGTTGCGCGT CATAGACCAGCGCCTCGCCGGTCTGCTCGGCGAACAGGCGGTGGATCAGCGGCGACTTGC TGTGGCCGATGGGGTTGCCGAATACGCAATAGCGGTCCATGGGTCGTTCCTTTGCCGGAG TGGGACGGGACGAGCGGACTCGTCCCCTGCGGGCGGGTCAGGGCTGGCCGGCGAGCCAAT CGCGGTCGGCGAGGAAATACTCGGTCA >Case 10 aroE Consensus TGACAACTCAGACAGTTGCCAACTGTCGGCGCAGCGTCTCCAACACTGGCGCCGAGGCAG GACGCACGCCGCGCCAGAGGAAGAATGCCTCGGCGGCCTGCTCCACCAGCATGCCCAGGC CATCCAGGGTACGCGCCGCACCGCGTTCGGCGGCCCAGCGGTTGAAGGCAGTCGGTTCCT TGGCATACATCATGTCGTAGCAGACGGTACGGCCGGGCTCGATCACGCTCTGCGCCAGCG GCGGCACGTCGCCGGCAAGACTGGCCGAGGTGCCGTTGACGATCAGGTCGAAAGGCCCTT CGACCTCGGCGAAACCGCAGCCGTGCACCGCGCCGAGGTCGGCGAACCGCTCGGCCAGGT CCACGGCCTTCCGCGCCGTGCGGTTGGCGATCAGCAACTCCGCCGGGCACTCGCCGAGGA AGGGTTCGAGCACCCCACGCACCGCACCGCCGGCGCCGAGCAGGAGAACCCGCTTGCCGC GCAGCTCGACCCCGGCGTTCGCCGTCAGGTCCCGCAGCAGGCCGGCGCCGTCGGTGTTGT CGCCGCGCAGGCGACCGTCGGCGAGGCGGATCAGGGTGTTCACCGCCCCGGCCCGGGTGG CCCGCTCGCTCAACTCGTCCACCAGACGATAGGCCTCTTCCTTGAACGGCACGGTGACAT TGGCGCCCTTGCCCTGCTCGAAGAAGCGCCGGGCGAACCCGGGGAAATCGTCCAGCGGCG CCAGTTGCGCGTCATAGACCAGCGCCTCGCCGGTCTGCTCGGCGAACAGGCGGTGGATCA GCGGCGACTTGCTGTGGCCGATGGGGTTGCCGAATACGCAATAGCGGTCCATGGGTCGTT CCTTTGCCGGAGTGGGACGGGACGAGCGGACTCGTCCCCTGCGGGCGGGTCAGGGCTGGC CGGCGAGCCAATCGCGGTCGGCGAGGAAATACTCGGTCAGGCGCGCTTCCTCGCTGCCGG CTCGGGTTTCCA