Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules

1. Genomic responses in mouse models poorly mimic human inflammatory diseases
2. From the Cover: Automated reconstruction of ancient languages using probabilistic models of sound change
3. PNAS Plus: Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome
4. In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment.
5. Colloquium Papers: From wild animals to domestic pets, an evolutionary view of domestication

50 Most-Read Articles »

1. DNA sequencing with chain-terminating inhibitors
2. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.
3. Cluster analysis and display of genome-wide expression patterns
4. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
5. Significance analysis of microarrays applied to the ionizing radiation response

50 Most-Cited Articles »