IDOL Stimulates Clathrin-Independent Endocytosis and Multivesicular Body-Mediated Lysosomal Degradation of the Low-Density Lipoprotein Receptor

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Fig. S1 (Specificity of commercial IDOL antibodies), S2 (IDOL degradation of AP-tagged LDLR), S3 (IDOL and LDLR colocalization at the plasma membrane), S4 (Clathrin silencing and transferrin internalization), and S5 (USP8 silencing and IDOL-dependent degradation of VLDLR) and legends to Videos S1 and S2

  PDF, 2.1M

• Supplemental file 2 -

  Video S1 (IDOL colocalization with LDLR at the plasma membrane)

  AVI, 4.9M

• Supplemental file 3 -

  Video S2 (IDOL and LDLR cotransportation in living cells)

  AVI, 2.4M