Staphylococcus epidermidis Esp Degrades Specific Proteins Associated with Staphylococcus aureus Biofilm Formation and Host-Pathogen Interaction

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Supplemental materials and methods

  Table S1, cell-associated proteins that are degraded by Esp in the biofilm matrix fraction of S. aureus MR23

  Table S2, strains and plasmids

  Table S3, primers

  Fig. S1, proteolytic and biofilm-degrading activity of an Esp mutant

  Fig. S2, caseinolytic activity of proteases

  Fig. S3, degradation of cell wall-anchored proteins in the S. aureus biofilm by various proteases

  Fig. S4, identification of proteins degraded by Esp in the biofilm matrix fraction

  Fig. S5, cellular localization of Eap in the S. aureus biofilm

  Fig. S6, identification of proteins degraded by Esp in the S. aureus cell wall fraction

  PDF, 441K