Table 5. Infectivity of WT, ospC mutant, and complemented B. burgdorferi clones in mice by intradermal and intra-articular inoculation

Clone	Infection route	Mice infected/analyzed
		Seroconversion	Reisolation*
B31-A3	i.d.^†	2/2	2/2
	i.a.^‡	3/3	3/3
ospC7	i.d.^†	0/3	0/3
	i.a.^‡	0/3	0/3
ospC7/ospC⁺4	i.d.^†	3/3	3/3
	i.a.^‡	3/3	3/3

*Spirochetes were cultured from the inoculation site (neck skin or knee, as appropriate), ear skin, and ankle joint. All three tissues were culture-positive for each mouse injected with B31-A3 or ospC7/ospC⁺4.

^{†Inoculation by intradermal (i.d.) route into the neck skin with 5 ´
10³ spirochetes.
^{‡Inoculation by intra-articular (i.a.) route into the knee with 5 ´
10³ spirochetes.}}