Table 8. Top 50 ORFs induced by ethanol starvation ORF Gene Fold of Induction MIPS function YBL075c SSA3 86 "heat shock protein of HSP70 family,cytosolic" YGR236c SPG1 84 questionable ORF YPL223c GRE1 41.8 induced by osmotic stress YHR097c 41.2 strong similarity to hypothetical protein YDR348c YBL078c AUT7 40.5 essential for autophagy YDL218w 35.2 weak similarity to hypothetical protein YNR061c YPL128c TBF1 24.9 telomere TTAGGG repeat-binding factor 1 YDL169c UGX2 21.9 protein of unknown function YHR096c HXT5 20.4 strong similarity to hexose transporters YMR107w 18 hypothetical protein YML058w SML1 16.5 "Protein that negatively affects dNTP pools, binds ribonucleotide reductase and inhibits its activity" YNL202w SPS19 26.9 "peroxisomal 2,4-dienoyl-CoA reductase" YDR329c PEX3 24.8 "peroxisomal assembly protein, peroxin" YDR256c CTA1 18.3 "catalase A, peroxisomal" YIL160c POT1 17.2 "acetyl-CoA C-acyltransferase, peroxisomal" YPL147w PXA1 16.4 long-chain fatty acid transporter YHR139c SPS100 76.5 sporulation-specific wall maturation protein YOR031w CRS5 22.1 suppressor of cup1 deletion YDR111c 37.1 strong similarity to alanine transaminase TY1B_OL TY1B 35.4 TY1B protein YDR380w ARO10 35.1 Putative indole-3-pyruvate decarboxylase YDR277c MTH1 25.1 repressor of hexose transport genes YER162c RAD4 24.4 excision repair protein YOR393w ERR1 22 enolase related protein YBR150c TBS1 21.7 weak similarity to transcription factors YBR212w NGR1 21.4 glucose-repressible RNA-binding protein YOR032c HMS1 20 weak similarity to DNA-binding proteins YAL061w FUN50 19.9 similarity to alcohol/sorbitol dehydrogenase YDL085w NDH2 19.8 Mitochondrial NADH dehydrogenase (ubiquinone) YNL093w YPT53 19 GTP-binding protein of the RAB family (RAS superfamily) YHR146w CRP1 18.3 similarity to pheromone-response G-protein Mdg1p YML070w DAK1 18 "dihydroxyacetone kinase, induced in high salt" YMR323w 17.5 strong similarity to phosphopyruvate hydratases YMR280c CAT8 16.9 transcription factor involved in gluconeogenesis YFR034c PHO4 15.4 transcription factor YDL222c 21 strong similarity to hypothetical protein YNL194c and similarity to YML052w YDR262w 17 hypothetical protein YER150w SPI1 21.4 Stationary Phase Induced YJL144w 17.6 hypothetical protein YKR075c 17.2 weak similarity to negative regulator Reg1p YML118w 19.2 similarity to YMR285c YMR075c-a 20.4 questionable ORF YMR135c 20.4 hypothetical protein YMR191w 23.2 hypothetical protein YMR192w 41.8 similarity to mouse Tbc1 protein YMR322c 18.3 "strong similarity to YPL280w, YOR391c and YDR533c" YNL194c 29.4 strong similarity to YDL222c and similarity to Sur7p YNL203c 42 weak similarity to B.subtilis CDP-diacylglycerol--serine O- phosphatidyltransferase YNL285w 20.3 hypothetical protein YNL305c 26.7 similarity to C-term. of A.nidulans regulatory protein (qutR)