Fig. 8. Lineweaver-Burk plots for the ability of PMEApp to inhibit the catalytic activities of EF3 (A) and its mutants EF-K372A (B), EF-N583A (C), and EF-H577N (D). The concentrations of PMEApp used were 0, 0.15, 0.3, and 0.6 m M.