Significant Modifications of the Salivary Proteome Potentially Associated with Complications of Down Syndrome Revealed by Top-down Proteomics

Supplemental Data

Files in this Data Supplement:

• Supplemental Table S1 - Elution time, and experimental and theoretical monoisotopic mass values of tryptic fragments of cystatin C and its sulfoxide derivative. The identification, based on the experimental mass values, was also confirmed by high resolution HPLC-ESI-MS/MS sequencing.
• Supplemental Table S2 - m/z values of the multiply-charged ions used for the XIC quantification of the peptides/proteins analyzed in the study.
• Supplemental annotated MS/MS spectra - Annotated MS/MS spectra of tryptic fragments of the Cystatin C and its sulfoxide derivative. Summary of the Proteome Discoverer Decoy search