Fig. 8.
Farnesoid X receptor (FXR) activators induce intimal phenotype rat aortic smooth muscle cell (RASMC) death. Images represent viability as percentage of control, control being 100% corresponding to untreated/vehicle-treated cells. (a) The effect of farnesol (Farn). (b) The effect of juvenile hormone III (JHIII) at 30, 100, or 300 m M, on the cell death induced by the retinoid X receptor (RXR) ligand 9-cis retinoic acid (9cRA). This data represents n = 12 from four separate experiments. Asterisk denotes P < 0.05 between control/ligand treatment alone and with 9cRA (by paired t test).