Critical Differences between Isoforms of Securin Reveal Mechanisms of Separase Regulation

Supplemental material

Files in this Data Supplement:

• Supplemental file 8 -

  Legends to Videos S1 to S7

  PDF, 52K

• Supplemental file 1 -

  Video S1 (Control HeLa cells)

  MOV, 455K

• Supplemental file 2 -

  Video S2 (PTTG1-expressing cells)

  MOV, 500K

• Supplemental file 3 -

  Video S3 (Degradation of APC/C biosensor in control cells)

  MOV, 347K

• Supplemental file 4 -

  Video S4 (Mitotic exit in ESP1-expressing cells)

  MOV, 1.1M

• Supplemental file 5 -

  Video S5 (Mitotic exit in PTTG1^H134R-expressing cells)

  MOV, 861K

• Supplemental file 6 -

  Video S6 (Mitotic exit in PTTG1^DΔ-expressing cells)

  MOV, 331K

• Supplemental file 7 -

  Video S7 (Mitotic exit in PTTG2^R134H+DΔ-expressing cells)

  MOV, 360K