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Fig. S1. Complementation of the dotA mutant of strain LPE509. Fig. S2. SdhA is not involved in the cell death induced by strain LPE509. Fig. S3. Evaluation of autophagy in the intracellular growth defect of LPE509 in A/J macrophages. Fig. S4. The IcmS/W chaperone complex is required for the cell death induction by LPE509. Fig. S5. The necrosis inhibitor necrostatin has no effect on intracellular growth and cytotoxicity of strain LPE509 and its derivatives in A/J macrophages. Fig. S6. Effects of caspase 3 and an apoptosis inhibitor on the cell death induced by LPE509 on A/J macrophage. Fig. S7. Glycine cannot rescue the intracellular growth defect of LPE509 in A/J macrophages.
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