Identification of Coxiella burnetii Type IV Secretion Substrates Required for Intracellular Replication and Coxiella-Containing Vacuole Formation

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Table S1, strains

  Table S2, plasmids

  Table S3, predicted PmrA-regulated ORFs

  Table S4, C. burnetii T4SS candidates possessing an E block motif

  Table S5, L. pneumophila effectors used for the identification of homologs in C. burnetii

  Table S6, genome comparisons of T4SS substrates identified in this study

  Fig. S1, newly identified secretion substrates are secreted by C. burnetii

  Fig. S2, Himar1 transposon insertion into C. burnetii T4SS substrate genes

  Fig. S3, C. burnetii growth defects are due to the loss of individual effector proteins

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