>ACD20 Concatenation of 3 sequences MAIRKLNPTSAGRRYMTIGDFAE-ITTD------------KP-EKSLLVSLNRRAGRNNTGRITCHH-KGCGHKRA---- YRIIDFK-R--DK-RGIPATVKTVEYDPNRNTRISLVVYA-DGEKRYILTPSDLKVGDTIQSGP-D-SE-IKTGNALPLS NIPLGTLVHNIELAPGKGGQLVRGAGGSAQVMAK--EGDYVTVKLPSSEMRMVHKNGYATVGVLGNSDAKNIRIGKAGRK -RWM-----GVK-P-TVRGVAKNAVDHPHGGGEGRS-P--IGGK-PQTP---WGKPALGYKTR-RTKQSD--K-YIVRKR --------------------------------MTL---G-VIGEKLGMTQVFN-DEGL---------VIPVTVVKVDPLT VTQVK----TVQ----K--DGY--NAIQVGT-------KP--GLTR----------PQLKHLK----------------- ---NN-LQTFRHLQEFRL--------DDVSEY-----NV---GQ-NVDL--S-I-LNEVEKVDVTGVSIGKGFQGTVKRY NFAR-GPMSHGS-KNHRL-PGSIGA-GTTPS-RVYKGLKMAGNMGNKTVTVKKLTVVKVDTEKN---------------- ----------IVLIKGS-VPGPEGRLVTIK--MSKQITL-SNGAQV-GQVDLDEKVF----GI-EP-NIHVMHLALRRQL NNARAGTASTKTRSE--------VR-GGGKKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPK-P-RDYSFSMPTKARRLALRSALSARTQD-------------------IKILQDF---TAIA-Q------ --PKTKLIV----ANAENQ---HLELSARNIPYVK-V---------------ILPSNINVKDILEADN----ILITESAI KDITERLKQRYSEDV----VPALTKQFGYTNSYEVPKLVKVVLNMGVG-EAVQNVKILDAAVQELTKITGQKPIVTRAKK SIATYKLRQGMPIGTMVTLRGQKMYDFLQKFIGVALPRIRDFRGVSD-KSFDGRGNYSIGLKEQTLFPEIS-----YDEV DMIKGMNISIITT-----------------------AKTDEEAKALLSELGMPFRSRIG-K--APVVIPDKVEVK-V--- -V-N--N-TVTAKGPLGTLSVTI--RP-E--IAVKQED-GK--VIL---ER-I--NEERKTR-ALHGLSRTLVYNLINGV NTGFSKNLEIHGVGY--RAAKEG-NV--LNLS--LGYSHPVKVDP-P-A-GIDIKVE--G-TNKITVTG-ADKQLVGDIA ALIRSKR------PPEVY---KGKGIRYQGEHIRKKAGK----------MIQQETRLNVADNTGAKTLLCIRVLG-SNKR Y--AGIGDVIVATVKDAAPN-M-------PVKKSDIVKAVIVRTKASLKRTDGTTIRFDENAAVIIN-KDGN-PTGTRVF GPVARELRE-KNYMKIVSLAPEVIIT-L--EDLRPADGA-THSKKRVG-RGRSSGH-GKTSTRGHNGEGQRSG---R--S QKRGF-E-GGQMPGYRKFPKHKG--FETINVSQIIDLEMLKDK-KLY-LR---------VLG--NGE-L-T-R-V-VTV- RARHFTKSAKEKIEAAGGKV-K---QMR--GRM---TGTE-TRGAALEYG----------DYGIQSM--EPAWINSRQIE AARRAMTRSI------KRGGQVWIRIFPDKPVTAKPAETRMGSGK---------GNPEYWVAVVKP-GRVLFEL--AG-- VDRATAVTALELAAQKLPIQVRI-IRKEIAAKRHSRIRVNL---SGTPQRPRLSVYRSNKHIYAQIIDD---I--KGVTV ASAGTT-EPTL-KERLP----HG-GDIDAAKEVGKLLAER--AK-KAGVESVVFDRGGFLYH--GRIAALADAAREGGLV F--------------------------------------------------------------ME-AKAKQKSIGMPARK IRRVINEVRGKKVDDAINILRFM---------------------------------PYAAARVIEKNLTAAIAN----A- SEKF-GAASEGLVISEIYADDGPMYKRARPRAQGRVYKRIRRTSQLTIKVSVKLHVKTGDRVLVISGK------DK-GKI GNIKKAMPKES--RVV--VEGVNIVTKAMK----PNP-MK-NIQ-GGLVKFEAPIQASNVM-LYCSKC-------EK--P --SRIRHEV---LE--------SGKVR---VCKKCG---EQV--MGQKVHPIGLRIG--II-KPWLSNWFA-------TK E--YADFLAEDDQIRKYV--KKKLY-----SAGISRIGIDRKA-Q-QVSLTIVTAKPGIVVGRGGQGIDELRKELSNRVQ IDVVEVAR---IDADAQLVSEAIAQQLEKRVVFRRAMKQAIQRAMRA-GVLGIKVSVSGRLGGAEIARTEWTKEGRIPL- -HTIRADIDYGVAEADTVMGIIGVKVWIFMMNTDPIADMLTRIRNGNIARHSSVEM-PSSKVKEQLAALLKSEGYIVDFE VKE----V---G----QFKVLSVDLKYG---KDK-------N---PVITNLRRISKPGLRVYKKSQNLPKVLDGLGVAIV STSKGLLTDRKARKEKVGGEVLCYVWTKRHRIRVCLKAYDHRLIDSSADKIVETAKRTDAKVAGPIPLPTRRKIYCVLRS PHVDKKSR-EHFETRVHKRIIDILDPTRQTTEELSRLDLPAGVDIEVKLKKEKFGRVVSNKMDKTVVVEVQEFRPHPIYK KIIAQTKNYMASDAG--IACNEGDEVRIVETKPVSKTKRWAVAEVVKKS------------------------------- -MARSL-KKGPFIQE-SLINKVEKMNK---TGDKR----VIKTWSRASMIVPEMLGHTIAVYNGKTHVPVYVTE-QMIGH KLGEFSPTRFFRGHA------G--SDK----TAK------RK >MEL.A2 Concatenation of 7 sequences MATRKINPTSPGQRGMIKSDYQE-ITTS------------TP-EKSLLKSLNKTAGRNNTGRITCRH-KGGGVKRS---- YRIIDFK-R--EK-FGVPATVKTIEYDPNRNVRISLCFYA-DGEKRYILTPEGLNVGDTIISGP-E-AP-VQVGNALPLE LIPLGTIVHNIELHPGRGGVMVRAAGNAAQVMAK--EGNYVTIKLPSSEMRMVRKECMATIGMLGNSEFKNLSIGKAGRK -RYL-----GIR-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGN-PKTP---WGKPALGYKTR-KKGKASD-K-LIVRRR --------------------------------MTL---G-VIGKKVGMTQIFD-EQGL---------AIPVTVIKVDETV VTQVK----TVE----T--DGY--NAIQVGT-------VA--ALTK----------AQLGHFK----------------- ---NN-LSSYRHLQEFRV--------DNPQDY-----KV---GD-KVEL--S-V-LDNVEKVDVTGKSIGKGFQGTVKRW NFGR-GPMAHGS-KNHRE-PGSIG-AGTTPS-RVIKGKRMAGNMGNERVTITKLKLVKVDSANG---------------- ----------LVLVKGS-VPGCEGRLVTI---MSKEIL--STTGEKLGEITLEKSVF----GV-EP-NLHVMHLALRRQL NNARQGNACAKTRAE--------VA-GGGRKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPK-P-RSYAFNMPQKARQLALKSALSARESQ-------------------IVVVKDF---STIA-E------ --PKTKIVA--NTKAEENK---NLELSARNIPSVK-L---------------LLPSNLNVKDLLEADF----VVMTESAV NEITERLQ------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------ME-AKARQTDIKMTARK LRRVINEVRGKAVIEAQDMLRFM---------------------------------PYFAARVVEKNLKAAVAN----A- REQY-GVGAESLKISQIFADESVTYKRARTRAQGRMYSRMKRTSHLTLVVSD---------------------------- -------------------------------------------------------------------------------- --------------------------------------------MGQKTHPTGFRVG--II-QDWASTWYA------KWK D--YKTFVAEDAKIRKFV--KKKLY-----AAGVSKIWIARKA-Q-NTTITVVTAKPGIVVGRGGQGIDELRQEVTKYVI INVVEVAR---IDADAQLVAESIAQQLEKRIAFRRAMKQAMQRTMRS-GVQGIKVMVSGRLGGAEIARSEWAKEGRIPL- -QTLRADVDYGFAEADTIMGKIG--------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------MKKNRIRVCLKAYDHKLIDVSAEKIVETAKRTDAKVAGPIPLPTKRRIYCVLRS PHVDKKSR-EHFEMRTHKRIIDIYEPTQQTMEELRRLDLPAGVDIEAR-------------------------------- -------------------------------------------------------------------------------- -MARSL-KKGAYVEE-ALQKKIDKMNA---NSEKK----VIKTWSRASMIVPDMLNHTIAVHNGKTHVPVYITE-QMVGH KLGEFAPTRLFKGHA------G--SDK----TAK------RG >MEL.C1 Concatenation of 15 sequences MAIRKINPTSPGQRGMTKSDYQE-ITCT------------TP-EKSLLKPLKKTAGRNNTGRITCRH-KGGGVKRT---- YRIIDFK-R--EK-FGVPATVKTIEYDPNRNVRISLVFYA-DGEKRYILTPEGLNVGDVIVSGP-E-AP-VQIGNALPLE LIPLGTIVHNIELTPGRGGVMVRSAGNAAQVMAK--EGNYVTIKLPSSEMRMVRKECMATIGTLGNSEFKNLSIGKAGRK -RYM-----GIR-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGH-PKTP---WGKPALGYKTR-KKGKASD-K-LIVRRR --------------------------------MTL---G-VIGKKLGMTQIFD-EQGL---------AIPVTVIKVDPIV VTQVK----TVE----K--DGY--NAIQVGT-------IA--ALTK----------AEIGHFK----------------- ---NN-LENFRHLQEFRI--------DNPQDY-----KV---GD-KIEL--S-V-LDNVEKVDVCGKSIGKGFQGTVKRW NFSR-GPMGHGS-KNHRE-PGSIG-AGTTPS-RVIKGKRMAGNMGNERVTITKLKLVKVDADNS---------------- ----------LVLVKGS-VPGCEGRLVTI---MSKEIL--STNGEKLGEITLNESVF----GV-EP-NLHVMHLALRRQL NNARQGSASCKTRAE--------VS-GGGRKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPQ-P-RDYSFNMPQKARKLALKSALSARSEQ-------------------MVVVKDF---STIT-E------ --PKTKIVA--DVKAAENK---YLELAARNIPSVR-I---------------ILPSNLNVKDLLEADS----VVITESAV NDITERLQ-KYQEEI----ISAMKEKFGYKNINQVPKLHKIVLNMGVG-EASHNSKIAEVIEAQLTKIAGQKCVVTKAKK SIASYKLREGMPVGAMVTLRGERMYDFLQKLICVVLPRIRDFRGISA-KSFDGRGNYTLGLKEQALFPEIT-----YEEV DLVKGMNVSIITT-----------------------AETDDEARELLRLLGMPFKSRIG-K--LPIEIPQGVEVT-I--- -N-G--Q-TVTAKGPHGTEVVEV--RP-E--IAVKVED-NH--IVL---SK-V--GTSRETD-ALYGLSRTLVANAVHGV KNLFEKKLEIQGVGY--RANMEG-KN--LNLS--LGYSHPVVVEP-P-E-GITITVE--A-NTKISVKG-ANKQTVGDVA AFIRSKR------PPEVY---KGKGVRYEGEHIRRKAGK----------MIQQETRLEVADNTGAKELLCIRVMGSSNKK F--AAVGDEIVAAVKDANPN-M-------PVKKSEVVRAVVVRTKADIKRNDGSVIRFDENAAVIIN-KDGN-PRGTRVF GPVARELR-DKGYMKIVSLAPEVI-------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------K---MMK--GNM---KGHE-TRGTKLEFG----------GYALQAQ--EPGWITSRQIE AARRAMTREI------KRGGNVWIKIFPDKPITAKPAETRMGSGK---------GNLEYWVAVVKP-NRILFEL--DY-- FDRNVAVHALELAAQKLPIKVKV-VRKPKTQKRHRSIRIKL---SGTAEFPRLAVYRSTKHIYAQLIDD---V--NHVTL ASASSN-DKEL-KEKL----AHG-GNIEAAKLVGEEIAKK--AKVKG-IECVVFDRGGFLYH--GRVAALADAAREAGLM F--------------------------------------------------------------ME-AKSRQTDIKMTARK LRRVINEVRGKSVVEAQDMLRFM---------------------------------PYFAARVVEKNLKAAVAN----A- QEKY-GVSAESLKVSEIFADESVSYKRARTRAQGRMYSRLKRTSHLTLKVSDKLHVKNTDRVMIIAGK------DK-GKE GNIKKVNIAEG--TVT--VEGLNMVTKAQK----PQP-MA-GIQ-GGLIKIEAPLDASKVM-VVCPAC-------EK--P --TRIKHEV---V---------DGKVR---VCKKCG---EQL--MGQKTHPTGFRIG--II-QPWVSTWFA------KVK D--YGQFVAEDAKIRKFI--KKKLY-----TAGISKILIARKA-Q-NTTVTVVTAKPGIVVGRGGQGIDDLKKEVSKYII INVVEVAR---IDADAQLVAEAIAQQLEKRVAFRRAMKQAMQRTMRA-GAQGIKVMVSGRLGGAEIARSEWAKEGRIPL- -QTLRADVDYGFTEADTIMGKIGVKVWVFMMNTDPIADMLTRIRNANMVSHSTVEM-PSSKLKVQLAKLLKEEGFITDYN VKE----V---G----KFKVLEITLKYD---AKN-------K---PIITKLERISKPGLRSYSKAKNLPKVLGGMGIAIV STSKGLLTDRKARKENIGGEVLCYVYMKRQRIRVCLKAYDHKLIDVSSDKIVETAKRTDAKVAGPIPLPTKRRIYCVLRS PHVDKKSR-EHFEMRTHKRIIDIYEPTQQTVEELGRLDLPAGVDIEVKLKKEKQGIVISNKMDKTIVVKVADYEPHPKYK KIIESNKNYKAHDEN--NVCSEGDIVRIIESRPISGDKRWTLAEVVEKA------------------------------- -MARSL-KKGPYVEE-ALQNKIAKMNA---NSEHK----VIKTWSRASMIVPDMLGHTIAVHNGKTHVPVYVTE-QMIGH KLGEFAPTRLYKGHA------G--SDK----TAK------RK >MEL.C3 Concatenation of 15 sequences MGIRKINPTSPGQRGMTKSDFAE-ITTD------------KP-EKSLLRPMKKKSGRNNTGRITCRH-KGGGAKQS---- YRVIDFK-R--NK-FDVPGKITTIEYDPNRNVRISLVIYA-DGEKRYILTPEKLNVGDMIMSGP-N-AE-VNVGNAMPLE MIPLGTMVHNIEMVAGNGGVMVRTAGAGAQVMAK--EGNYVTIKLPSSEMRMVRKECLATIGVLGNAEYKNMQIGKAGRK -RHM-----GVK-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGH-PRTP---WGKPALGYKTR-NKKKASS-K-LIVRGR --------------------------------MTL---G-IIGEKLGMTQIFD-DKGL---------VIPVTVLKVEPLV VAQIK----TKE----T--DGY--NAVQLAY-------CQ--GMTK----------AEIGHLK----------------- ---NE-IGAYRHLKEFRV--------DNPGDY-----KV---GQ-QITV--E-A-LTGVEKVDVTAKSIGKGFQGTVKRW NFGR-GPMAHGS-KNHRE-PGSIG-AGTTPG-RVIKGKKMAGNMGNENVTIAKLKVVQIDKENN---------------- ----------LLLIKGS-VPGPEGKFVTV---MTKELSILDTKGAEVGQISVDEKVF----CV-EP-NVHVMHMALRRQL NNGRAGTACAKTRAM--------VS-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----LF---- AGGGVSFGPV-P-RDYSFKMPLKVRRLALKSALSSRLLN-------------------STVVKDF---SQIN-E------ --PKTKI------------------------------------------------------------------------- ---------RYNEEV----VNTLMEKFGYKNRHQVPKLNKIVINMGMG-EHSHNSKMVDLLVNQLTKIAGQKAVVTRAKK SIASYKLREGMAVGATVTLRQERMYDFLQKLNAVVLPRIRDFRGISN-KSFDGRGNYTFGLKEQSLFPEIG-----YDEI DAVQGMDISIVTT-----------------------ANTDDEARALLTELGVPFKSRIG-K--LPVLIPDGVEIK-I--- -D-G--Q-KITAKGPLGVEEVVV--CP-E--ITLEKED-NK--IIV---KR-I--NDERKSR-SLHGLSRTLINNAVHGV KEGFVKRLEIQGVGY--RANMQG-TS--LNLQ--LGYSHPVIVEP-P-Q-GIKIEVE--A-NTKISVKG-TNKQLVGDVA ADIRSKR------PPEVY---KGKGVRYEGEYIRRKAGK----------MIQQETRLAVADNTGAKELLCIHVMGSSNKK Y--AHVGDVITATVKEASPN-M-------TVKKSEVVKAVVVRTKADIKREDGSVIRFDENAAVIIN-KDGN-PRGTRVF GPVARELR-EKNFMKIISLAPEVI-------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------K---RMK--GRM---KGHE-TRGTKLEFG----------TYGLIAC--DPAWITSRQIE AARRAMTREI------KRGGNVWIKIFPDKPITAKPAETRMGKGK---------GNPEYWVAVVKP-GRVLFEL--EY-- SDRNIAVNALKLAAQKLPIKVKI-IRKEQTRKRHARVRVKI---SGTPECPRLAVYRSLKHISVQIIDD---V--NHITL VSASSN-DKEL-KQQL----KHG-GNVEAAKVVGEAIAKR--ALAKD-IKDVVFDRGGFLYH--GRVAALAEAAREGGLN F--------------------------------------------------------------ME-AKARQTNIKMPARK LRRVINEVRGKSCDEAIKILKFM---------------------------------PYFAAKVVEKNLIAAIAN----A- NEKL-GVGSSNLKISEIFADESVTYKRARPRAQGRMYKRFKRTSHLTLKVMKNIHVRTGDRVVVLAGK------DK-GKV ANIKKVITAGS--KVV--VEGVNMVTKATK----PNP-MA-GVQ-GGLIKVEAPMDSSNVM-LYCLSC-------EK--P --TRVSHKI---V---------DGKVR---VCKKCG---EQL--MGQKTHPTGFRVG--II-QPWASTWFA-------TK E--YPQFVAEDAKIRKFI--KKKLY-----TAGISKILIARKA-S-NVLITVVTAKPGVVVGRGGQGIEEMRAAVAKLVT LDVVEVAK---IDADAQLVAEQIALQLEKRIAFRRAMKQAMQRTMRS-GVQLWYQDV----------------------- -----------------------------MMTTDPIADMLTRIRNANIVHHVDVAM-PSSKLKVELAKLLKEEGFIVDYN ETV----N---D---KNHKILTVELKYD---MQN-------K---PVIKNLKRVSKPGLRIYSKCKDLPKVMGGLGVAVV STSNGLLTDRKARKANLGGEVLCYVWMSRQRIRVCLKAYDHKLIDLSAEKIVETAKRTEAKVAGPIPLPTRRRIYCVLRS PHVDKKSR-EHFERRIHKRIIDIYEPTHQTTEELSRMDLPSGVDIEVKLKREKQGVVVSNKMDKTVVVAVSEYTPHKKYK KIIETTKNYKAHDEN--NVCNTGDVVRVIESKPISGDKRWRVVEVVEAA------------------------------- -MARSL-KKGPYVHE-SLLKKVEKMNE---NNEKK----VIKTWSRSSMIIPDMLGHTIAVHNGKSHVPVYVTE-QMVGH KLGEFAPTRLFKGHA------G--QDK----TAK------RK >MEL.A1 Concatenation of 16 sequences MAIRKINPTSPGQRGMTKSDYQE-VTTS------------TP-EKSLLKSLKKTAGRNNTGRITCRH-KGGGVKRT---- YRIIDFK-R--EK-FGVPATVKTIEYDPNRNVRISLVFYA-DGEKRYILTPEGLNVGDVIVSGP-E-AP-VQTGNALPLE LIPLGTIVHNIELIPGRGGKMVRSAGNAAQVMAK--EGDYVTIKLPSSEMRMVRKECMATIGTLGNSEFKNLSIGKAGRK -RYL-----GIR-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGH-PKTP---WGKPALGYKTR-KQGKASD-K-LIVRRR --------------------------------MTL---G-VIGKKLGMTQIFD-EQGL---------AIPVTVIKVDPIV VTQVK----TVE----T--DGY--NAIQVGT-------IA--ALTK----------AEIGHFK----------------- ---NN-LENFRHLQEFRV--------DNPADY-----KV---GD-KIEL--S-V-LDNVEKVDVTGKSIGKGFQGTVKRW NFSR-GPMGHGS-KNHRE-PGSIG-AGTTPS-RVIKGKRMAGNMGNERVTITKLKLVKVDAANS---------------- ----------LVLVKGS-VPGCEGRLVTI---MSKEIL--STNGEKLGEIALNEAVF----GV-EP-NLHVMHLALRRQL NNARQGSASCKTRAE--------VS-GGGKKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPK-P-RSYAFNMPQKARQLAIKSALSARSEQ-------------------LVVVKDF---STIA-E------ --PKTKIVA--DVKADENK---NLELAARNIPSVK-I---------------ILPSNLNVKDLLEADF----VVMTESAV NDITERLQ-KYQEEI----IPALTEKFGYKNINQVPKLHKIVLNMGVG-EASHNSKIAEAIEAQLTKIAGQKCVVTKAKK SIASYKLREGMPVGAMVTLRGERMYDFLQKLICVVLPRIRDFRGISP-KSFDGRGNYTLGLKEQALFPEIT-----YEEV DLVKGMNVSVITT-----------------------AETDEEARELLKLLGMPFKSRIG-K--KPIEIPNGVEVK-I--- -E-D--H-QVTVKGPNGTEVVKV--RP-E--IAIKMED-NH--IVL---SK-V--GETRETD-ALFGLFRTLIANAVHGV THLFEKKLEIQGVGY--RASMEG-KN--LNLA--LGYSHPVIVEP-P-E-GITITVE--A-NTKISVKG-ANKQTVGDVA AFIRSKR------PPEVY---KGKGVRYEGEHIRRKAGK----------MIQQETRLEVADNTGAKELLCIRVMGSSNKK F--AAVGDEIVAAVKDANPN-M-------PVKKSEVVRAVVVRTKADIKRADGSVIRFDENAAVIIN-KDGN-PRGTRVF GPVARELR-DKGYMKIVSLAPEVIIT-L--EDLRPAEGA-THKSKRVG-RGRSSGH-GKTSCRGNNGEGQRSG---N--S AKRGF-E-GGQMPGYRQMPKLKG--FKLINVGRIVSLEVLKEA-GRVHLR---------VLG--NGE-L-K-D-A-ITV- KACYVTPSAKEKIEKAGGKV-K---MMK--GRM---KGTE-TRGTQLEFG----------GYALQAV--EPGWITSRQIE AARRAMTREI------KRGGNVWIKIFPDKPITAKPAETRMGSGK---------GNLEYWVAVVKP-NRILFEL--DY-- FDRSVAVHALELAAQKLPIKVKV-VRKPKVQKRHKSIRVKL---AGTAEFPRLAVYRSTKHIYAQLIDD---D--NHVTL ASASSN-DKEL-KEKL----AHG-GNIEAAKLVGEEIAKK--AKVKG-IECVVFDRGGFLYH--GRVAALADAAREAGLM F--------------------------------------------------------------ME-AKARQTDIKMTARK LRRVINEVRGKSVVEAQDMLRFM---------------------------------PYFAARVVEKNLKAAVAN----A- QEKY-GVGAESLKVSEIFADESVTYKRARTRAQGRMYSRLKRTSHLTLKVSDKLHVKNTDRVMIIAGK------DK-GKD GNIKKVDVAKG--TVT--VEGLNMVTKAQK----PQP-MA-GIQ-GGLIKVEAPVDASNVM-VICPAC-------EK--P --TRIKHAV---V---------DGKVR---VCKKCG---EQL--MGQKTHPTGFRIG--VI-QPWVSTWFA------KVK D--YGAFVAEDAKIRKFI--KKKLY-----TAGVSKILIARKA-Q-NTTVTVVTAKPGIVVGRGGQGIEDLKKEVSKYII INVVEVAR---IDADAQLVAEAIAQQLEKRIAFRRAMKQAMQRTMRA-GAQGIKVMVSGRLGGAEIARSEWAKEGRIPL- -QTLRADVDYGFTEADTIMGKIGVKVWIFMMMTDPIADMLTRIRNAMMASHANVTM-PASKLKEQLAKLLKEEGYISDYI VKA----E---G----KFNVLEITLKYD---AKN-------K---PVITKLERISKPGLRNYSKAKDLPKVLGGMGIAVV STSKGLLTDRKARKENIGGEVLCYVYMTRQRIRVCLKAYDHKLIDVSSDKIVETAKRTEAKVAGPIPLPTKRRIYCVLRS PHVDKKSR-EHFEMRTHKRIIDIYEPTQQTVEELGRLDLPAGVDIEVKLKKEKQGVVISNKMDKTIVVKVADYEPHPKYK KIMESNKNYKAHDPE--NICNEGDIVRIVEARPTSKDKRWALAEVVEKA------------------------------- -MARSL-KKGPYVEE-ALQNKIAKMNA---NSEKK----VIKTWSRASMIIPDMLGHTIAVHNGKTHVPVYVTE-QMIGH KLGEFAPTRLFKGHA------G--SDK----TAK------RK >MEL.B1 Concatenation of 16 sequences MAIRKINPTSPGQRGMTKSDYQE-ITTS------------TP-EKSLLKKLNKTAGRNNTGRITCRH-KGGGVKQA---- YRIIDFK-R--EK-FGVPATVKTIEYDPNRNVRISLVFYA-DGEKRYILTPEGLNVGDVIVSGP-E-AA-IQTGNALPLE LIPLGTIVHNIELEPGRGGKMVRSAGNFAQVMAK--EGNYVTIKLPSGEMRMVRKECMATVGTLGNAEFKNLSIGKAGRK -RYM-----GVR-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGH-PKTP---WGKPALGYKTR-KKNKASD-K-LIVRRR --------------------------------MTL---G-VIGKKVGMTQIFD-SEGL---------AVPVTVIKVDSIV VTQVK----TVE----T--DGY--NAIQVGT-------IA--ALTK----------AEIGHFK----------------- ---NG-LNNYRHLQEFRV--------ENPADF-----KV---GQ-EIDL--S-V-LNDVQKVDVTGTSIGKGFQGTVKRW NFGR-GPMAHGS-KNHRE-PGSIG-AGTTPS-RVIKGKRMAGNMGNERVTITKLKLVKVDSENG---------------- ----------LVLVKGS-VPGCEGRLVTI---MSKQLL--NTNGEKLGEITLNEAVF----GV-EP-NLHVMHLALRRQL NNARQGSACAKTRAE--------VS-GGGKKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPK-P-RSFEINMPQKARKLALKSALSAREEQ-------------------LVVVKDF---SAIT-E------ --PKTKVIA--DTTAEENK---YLSLAAGNIPSVK-L---------------LLPSNLNVKDLLEADF----VVMTEKAV NDVTERLQ-KYNEEV----KAALKEKFGYENDMMIPKLHKIVLNMGVG-EASHNSKIADAIQAQLTKIAGQKAMVTKAKK SIASYKLREGMPVGAMVTLRGERMYDFLQKLICVVLPRIRDFRGISA-KSFDGRGNYTLGLKEQSLFPEIT-----YEEV DLVKGMNVSIITT-----------------------ANTDDEARELLRLLGMPFKSRIG-K--KPIEIPSGVEVK-I--- -E-G--N-VITAKGPKGTESITF--RE-E--VKVSVAD-NH--IIV---EP-N--SDDRKTN-ALHGLYRTLIANAIHGV SQGFEKKLEIVGVGY--RANMEG-SN--LNMA--LGYSHPVLIVP-P-A-GVTLSVE--A-NTKISVKG-SNKQTVGDVA AFIRSKR------PPEVY---KGKGVKYEGEHIRRKAGK----------MIQQETRLVVADNTGAKELLVIRVMGSSNKK F--AAVGDVVVATVKDATPN-M-------TVKKSEVVKAVIVRTKHDIKRADGSVIRFDENAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFMKIVSLAPEVIIL-L--EDLRPAEGS-TGKSKRVG-RGRSSGH-GKTSCRGHNGEGQRSG---R--T SKRGF-E-GGQMPAYRRLPKLKG--FQIINVGRLISLASLKEI-RKAHLR---------ILG--GGE-I-K-K-A-ITV- KADYVTPSAKEKIEAAGGKV-K---MMK--GRM---KGTE-TRGTEFEFG----------RYALKAL--EPGWITSRQIE AARRAMTREI------KRGGNVWIKIFPDKPITAKPAETRMGSGK---------GNVEYWVSVVKP-NRILFEL--DY-- FDRAVAINALELAAQKLPIKVKV-IRKPKVQKRHQAIRVKL---SGTSEFPRLAVYRSTKHIYAQLIDD---E--KHVTI CSASSV-DKDL-KEKL----AHG-GNIDAAKVVGEAIAKK--ALKAG-IECVVFDRGGFLYH--GRVAALADAAREAGLM F--------------------------------------------------------------ME-AKARQTNIKMTARK LRRVINEVRGKAVNDALDMLRFM---------------------------------PYFAARVVEKNLKAAAAN----A- FEQA-GVKSDALKVSEIFADESVTYKRGKPRAQGRIYRRLKRTSHLTIKVSDSLHVKTGDKVIITAGK------DK-GKT GNIKKSIPSES--QVV--VEGINMITKATK----ANP-AY-GIQ-GGLIKKEAPIDSSNVM-IVCPSC-------EK--P --TRIKHAV---V---------DGKVR---VCKKCG---EQL--MGQKTHPTGFRVG--II-RPWSSTWFA------KIK D--YAEFVAEDAKIRKFI--KKKLY-----AAGVANILIDRKS-Q-NTTITVVTAKPGIVVGRGGQGIEELKAEVSKYVI INVVEVAR---IDVDALLVAESVAQQLEKRIAFRRAMKQAMQRTMRA-GAQGIKIMVSGRLGGAEIARSEWAKEGRIPL- -QTLRADVDYGFTEADTIMGKIGVKVWIFMMNTDPIADMLTRIRNANIVSHPSVEM-PSSKLKVALAKLLKSEGFITDYS ERA----E---G----HFKYLTIELKYD---EAN-------K---PVISNLKRVSKPGLRNYCKAKNLPQVLGGMGIAIV STSKGLLTDRKARKENLGGEILCYVWMKRQRIRVCLRSYEHKLVDVSAEKIVETAKRTDAKVAGPIPLPTKRRIYCVLRS PHVDKKSR-EHFEIRTHKRIIDIYEPTQQTTEELSRLDLPAGVDIEVKLKKEKQGVVISDKMDKTVVVKVASYNPHPKYK KIIESNKNYKAHDEK--NECGIGDTVRIIESKPISGSKRWVVESIVEKA------------------------------- -MARSL-KKGPYVEE-ALQKKINKMNE---NSEHK----VVKTWSRASMIIPDMLGHTIAVHNGKTHVPVYVTE-QMIGH KLGEFAPTRMYRGHA------G--SDK----TAK------RK >MEL.B2 Concatenation of 16 sequences MGKKVINPTSPGQRGMIKDDFAD-ITTS------------KP-EKSLLKPIRKTAGRNNTGRITCRH-KGGGVKRA---- YRVIDFK-R--EK-FGVPGVVKTIEYDPNRNVRISLVFYA-DGEKRYILTPQNLNVGDTIVSGP-N-AD-IMTGNALPLE MIPLGTMIHNVEMIPGRGAKLVRTAGAAAQLMAK--EGNYVTIKLPSSEMRMIRKECLATIGVLGNAEQKNMKIGKAGRK -RYM-----GIR-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGH-PKTP---WGKPALGYKTR-KSNKHSD-K-YIVRGR --------------------------------SRL---G-VVGKKLGMTQVFD-EQGL---------AIPVTVIKVDPLT VTQVK----TVD----S--DGY--NAIQVGF-------EP--ALTK----------AQIGHFK----------------- ---NG-LDNFRHLQEFRV--------ENSSEY-----KV---GQ-QIDL--S-I-LENVEKVDVTGKSVGKGFQGTVKRW NFSR-GPMGHGS-KNHRE-PGSIG-AGTTPS-RVIKGKRMAGNMGNERVTITKLKVVQVDKDSN---------------- ----------LLLVKGS-VPGPEGKMVTV---MTKEVSILNTKGSAVGQIALDEKVF----GV-EP-NLHVMHLALRRQL NNGRAGSACTKTRAE--------VS-GGGRKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPK-P-RDYGFAMPQKARRLALKSALSARIDN-------------------TVLVKDF---SEIN-E------ --PKTKIIA--DVKAAENA---YLELSARNLPNVR-I---------------ILPSNLNVKDLLEADN----VIITEAAI NEITERLSKRYEEEV----KESLKSQFGYENVNQIPKLNKIVINMGVG-EACHNSKLAETIVKQLTKIAGQKAVITKAKQ SISSFKLREGMPVGCMVTLRGERMYDFLQKLICVVLPRIRDFRGISS-KSFDGRGNYTLGLKEQTLFPEIS-----YDEV DAVFGMNISIITT-----------------------AKTDEEARALLTELGMPFKSRIG-K--KPVVIPDGVEVK-I--- -D-G--Q-VVTAKGPLGTETVEL--RE-E--VTVKVEN-NEI-IVD---IK-D--HNDRKSR-ALWGLSRTLVNNAVEGV KHGFTKKLEIQGVGY--RANMEG-SN--LNLV--LGYSHPVLVTP-P-E-GIKISVE--A-NTKITVTG-SNKQMVGDVA AEIRGKR------PPEVY---KGKGVRYEGEYVRRKAGK----------MIQQETRLVVADNTGAKELLCIRVMGSSNKK F--AHVGDVIVATVKDATPN-M-------AVKKSDVVKAVVVRTKADIKRADGSVIRFDENAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFMKIISLAPEVIIT-L--EDLRPAEGS-THRTKRVG-RGRSSGH-GKTSCRGHNGEGQRSG---S--S SKRGF-E-GGQMPSYRQMPKLKG--FTNINVKDIIDLTWLIEN-GKAHLR---------VLG--NGE-I-S-K-S-VTV- KARYFTPSAKEKIEKAGGKA-K---KMK--GRM---KGHE-TRGTKLEFG----------NYGLIAC--DPAWITSRQIE AARRAMTRNI------KRGGNVWIKIFPDKPITAKPAETRMGKGK---------GNPEYWVAVVKP-GRVLFEL--EF-- GQRDVAIESLKLAAQKLPIKVKI-IRKEQTRKRHIRVRTKI---SGTAEAPRLAVYRSTKHIYAQLIDD---V--AKVTL CSASSI-DKDL-REKL----GHG-GNVEAAKVVGEAIAQK--ALKAG-INECVFDRGGFLYH--GRVSALADAAREAGLN F-------------------------------------------------------------MQE-SMAKQTNISMPARK LRRVINELRGKSALEAAKILKFM---------------------------------PYFAARVVEKNLVAAIAN----A- NEKF-GANAEDLKISEIFADESATYKRGKPRAQGRIYRRLKRTSHLTVKLASDLHVKTGDRVILTSGK------DK-GKI GNVKKIIASEN--KVI--VEGANMITKAQK----PNP-MA-GIQ-GGLTKIEAPVDSSKVM-VYCSSC-------EK--A --TRIKHDI---V---------DGKVR---VCKKCG---EQL--MGQKTHPKGFRVG--II-EPWESTWHA------KRK D--YPEFVKEDDKLRKYI--KKRLY-----AAGISKILIARKA-Q-NVNITVVTAKPGIVVGRGGQGIEELRADVAKLVS IDVVEVAR---TDADAQLVSESIALQLEKRIAFRRAMKQAVQRTMRS-GVQGIKIMVSGRLGGAEIARSEWVKEGRIPL- -QTLRADVDYGFAEADTIMGKIGVKVWIFMMYTDPIADMLTRIRNANIVSHEVVEM-PSSKLKVELAKVLKEEGYITDYT EKE----V---G----KFKVLSITLKYD---ETH-------K---PVISNLKRISKTGLRVYSKAKDLPQVFGGLGIAII STSKGLMTDRKARKEKLGGEVICYVWMQRQRIRVCLKAYDHKLIDVSAEKIVETAKRTDAKVAGPIPLPTKRRLYCVLRS PHVDKKSR-EHFEMRIHKRIIDIYDPTQQTTEELSRMDLPAGVDIEVKLKKEKQGVVVSNKMDKTAVVKVAEYNKHPKYH KIIETHKNYKAHDAE--NSCGEGDVVRIIESRPISGDKRWVVAEIVEKA------------------------------- -MARSL-KKGPFVQE-SLQKKIAKMNE---AGEKK----VIKTWSRASMIVPDMLGHTIAVHNGKSHVPVYVTE-QMVGH KLGEFAPTRLFRGHA------G--QDK----TAK------RK >MEL.B2 Concatenation of 16 sequences MAIRKINPTSPGQRGMTKSDYQE-ITTS------------TP-EKSLLKKLNKTAGRNNTGRITCRH-KGGGVKQA---- YRIIDFK-R--EK-FGVPATVKTIEYDPNRNVRISLVFYA-DGEKRYILTPEGLNVGDVIVSGP-E-AA-IQTGNALPLE LIPLGTIVHNIELEPGRGGKMVRSAGNFAQVMAK--EGNYVTIKLPSGEMRMVRKECMATVGTLGNAEFKNLSIGKAGRK -RYM-----GVR-P-TVRGVTMNPCDHPHGGGEGKT-G--PGGH-PKTP---WGKPALGYKTR-KKNKASD-K-LIVRRR --------------------------------MTL---G-VIGKKVGMTQIFD-SEGL---------AVPVTVIKVDSIV VTQVK----TVE----T--DGY--NAIQVGT-------IA--ALTK----------AEIGHFK----------------- ---NG-LNNYRHLQEFRV--------ENPADF-----KV---GQ-EIDL--S-V-LNDVQKVDVTGTSIGKGFQGTVKRW NFGR-GPMAHGS-KNHRE-PGSIG-AGTTPS-RVIKGKRMAGNMGNERVTITKLKLVKVDSENG---------------- ----------LVLVKGS-VPGCEGRLVTI---MSKQLL--NTNGEKLGEITLNEAVF----GV-EP-NLHVMHLALRRQL NNARQGSACAKTRAE--------VS-GGGKKPW---------KQKGTGRAR--------AGS---LR-SP----LF---- AGGGVIFGPK-P-RSFEINMPQKARKLALRSALSAREEQ-------------------LVVVKDF---SAIT-E------ --PKTKVIA--DTTAEENK---YLSLAAGNIPSVK-L---------------LLPSNLNVKDLLEADF----VVMTEKAV NDVTERLQ-KYNEEV----KAALKEKFGYKNDMMIPKLHKIVLNMGVG-EASHNSKIADAIQAQLTKIAGQKAMVTKAKK SIASYKLREGMPVGAMVTLRGERMYDFLQKLICVVLPRIRDFRGISA-KSFDGRGNYTLGLKEQSLFPEIT-----YEEV DLVKGMNVSVITT-----------------------ANTDDEARELLRLLGMPFKSRIG-K--KPIEIPSGVEVK-I--- -E-G--N-VITAKGPKGTESVTF--RE-E--VKVSVAD-NH--IIV---EP-N--SDDRKTN-ALHGLYRTLIANAIHGV SQGFEKKLEIVGVGY--RANMEG-SN--LNMA--LGYSHPVLIVP-P-A-GVTLSVE--A-NTKISVKG-SNKQTVGDVA AFIRSKR------PPEVY---KGKGVKYEGEHIRRKAGK----------MIQQETRLVVADNTGAKELLVIRVMGSSNKK F--AAVGDVVVATVKDATPN-M-------TVKKSEVVKAVIVRTKHDIKRADGSVIRFDENAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFMKIVSLAPEVIIL-L--EDLRPAEGS-TGKSKRVG-RGRSSGH-GKTSCRGHNGEGQRSG---R--T SKRGF-E-GGQMPAYRRLPKLKG--FQIINVGRLISLASLKEI-RKAHLR---------ILG--GGE-I-K-K-A-ITV- KADYVTPSAKEKIEAAGGKV-K---MMK--GRM---KGTE-TRGTEFEFG----------RYALKAL--EPGWITSRQIE AARRAMTREI------KRGGNVWIKIFPDKPITAKPAETRMGSGK---------GNVEYWVSVVKP-NRILFEL--DY-- FDRAVAINALELAAQKLPIKVKV-IRKPKVQKRHQAIRVKL---SGTSEFPRLAVYRSTKHIYAQLIDD---E--KHVTI CSASSV-DKDL-KEKL----AHG-GNIDAAKVVGEAIAKK--ALKAG-IECVVFDRGGFLYH--GRVAALADAAREAGLM F--------------------------------------------------------------ME-AKARQTNIKMTARK LRRVINEVRGKAVNDALDMLRFM---------------------------------PYFAARVVEKNLKAAAAN----A- FEQA-GVKSDALKVSEIFADESVTYKRGKPRAQGRIYRRLKRTSHLTIKVSDSLHVKTGDKVIITAGK------DK-GKT GNIKKSIPSES--QVV--VEGINMITKATK----ANP-AY-GIQ-GGLIKKEAPIDSSNVM-IVCPSC-------EK--P --TRIKHAV---V---------DGKVR---VCKKCG---EQL--MGQKTHPTGFRVG--II-RPWSSTWFA------KIK D--YAEFVAEDAKIRKFI--KKKLY-----AAGVANILIDRKS-Q-NTTITVVTAKPGIVVGRGGQGIEELKAEVSKYVI INVVEVAR---IDVDALLVAESVAQQLEKRIAFRRAMKQAMQRTMRA-GAQGIKIMVSGRLGGAEIARSEWAKEGRIPL- -QTLRADVDYGFTEADTIMGKIGVKVWIFMMNTDPIADMLTRIRNANIVSHPSVEM-PSSKLKVALAKLLKSEGFITDYS ERA----E---G----HFKYLTIELKYD---EAN-------K---PVISNLKRVSKPGLRNYCKAKNLPQVLGGMGIAIV STSKGLLTDRKARKENLGGEILCYVWMKRQRIRVCLRSYEHKLVDVSAEKIVETAKRTDAKVAGPIPLPTKRRIYCVLRS PHVDKKSR-EHFEIRTHKRIIDIYEPTQQTTEELSRLDLPAGVDIEVKLKKEKQGVVISDKMDKTVVVKVASYNPHPKYK KIIESNKNYKAHDEK--NECGIGDTVRIIESKPISGSKRWVVESIVEKA------------------------------- -MARSL-KKGPYVEE-ALQKKINKMNE---NSEHK----VVKTWSRASMIIPDMLGHTIAVHNGKTHVPVYVTE-QMIGH KLGEFAPTRMYRGHA------G--SDK----TAK------RK >Acaryochloris_sp._CCMEE_5410 Concatenation of 16 sequences MGIRYYRPYTAGTRQKTSSDFAE-ITRD------------RP-EKSLVKAKHRAKGRNNRGVITSRR-RGGGHKRR---- YRIIDFY-R--NK-LGVPGTIATVEYDPNRNARIALVNYK-DGEKRYILHPRNVQVGTTIVAGP-D-AP-IEVGNALPLE RIPLGTEVHNVELIPGKGGQLARAAGALAQVVAK--EGKMVTLKLPSGEVRLFQKECYATIGQVGNVESNNITIGKAGRN -RWK-----ARR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGYKTR-KKKKQSN-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-EAGR---------SIPVTVVQAGPCP VTQIK----TAQ----T--DGY--TAIQIGY-------GS--ALTR----------PELGHLK----------------- ---SG-STPVRHLQEYRL--------ADVSEY-----EL---GQ-SISA--D-L-FSEGQLVDISGTSIGRGFAGYQKRH NFRR-GPMGHGS-KNHR-APGSTG-AGTTPG-RIYPGKRMAGQMGNVKKTIRKLTVVRVDAERN---------------- ----------VLLIKGS-VPGKPGALLNIQ--MVNCVV-RNWQGEDAGQAELDLKVA----NE-EN-AAHIVHRALRRQM NNARQGTASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---SR-SP----LW---- RGGGVIFGPK-P-RSYSTKMNRKERRLALRTAFASRAED-------------------LVVVEDF--GDNLS-R------ --PKTKLLI--LADKH--D---TIYLSARNVEKLK-L---------------ILASNLNVYDLLAADQ----IVATQSAI AKIQERLKTLYLDTA----VPKLQEQFKYKNAHEIPKVTKVSVNRGLG-EASQNAKALERSLEELAVITGQRPVVTRAKK AIAGFKIRQGMPVGVMVTLRGERMYAFLDRLVNLALPRIRDFRGVSP-KSFDGRGNYTLGLREQLIFPEVD-----YDSI DQIRGMDISIITT-----------------------AKTDEEGRALLKVLGMPFRSRIG-K--VPIPIPDKVNVT-I--- -K-G--Q-AVTVKGPKGELSREI--TP-E--VAIEQAD-NL--VTV---TR-R--NESRIAR-QRHGLSRTLIANMVEGV SKGFEKKLQIQGVGY--RAQVQG-RN--LILN--VGYSNPVTIEP-P-E-GVQVAVE--S-NTNVIVSG-INKEVVGNTA ARIRAVR------PPEPY---KGKGIRYADEYVRRKVGK----------MIQQETTLNVADNSGAKRLLCIRVIGGGNRR Y--GGVGDVIIATVKDATPN-M-------PVKKSDVVRAVIVRTRKSICRESGMSIRFDDNAAVLIN-PDGN-PRGTRVF GPVARELR-DKSFTKIVSLAPEVLMR----------------------------------------GQKSRSG---R--P TRPGF-E-GGQNPLYRRVPKLKH--FTLINVGKLVTLESLMAE-GIITLK---------VLG--DGE-L-T-V-A-LNV- QAAAATQSAIAKIEGAGGSFQKFRKQHR--GRM---RGKA-TRGNTLSFG----------DYGLQAL--EPSWITSRQIE AGRRAMTRYV------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMYEM--NG-- VPESTAREAMRLAAFKMPIKTKF-VRRDATRSRHQRVRRKV---VGTAERPRLAVFRSNQHIYAQVIDD---S--QQHTL AAASTV-ESDL-KSSS------G-ATCDASTAVGKLVAER--AIEKG-IKAVVFDRGGNLYH--GRVKALADAAREAGLE F--------------------------------------------------------------MT--YAKAKYIRMSPRK VRRVLDQIRGRSYREALIVLEFM---------------------------------PYRACEPVLKVLRSAVAN----A- ETNR-GLDPVDLVVSHAYADQGPRLKRFRPRAQGRAYQIQKPTCHITIAVSAKMHVKKGDTVQVIAGK------DK-AKV GEVIDVLPKLS--QVV--VEGVNIKTKHVK----PR--SE-SES-GQISTVEFPIHSSNVM-LYSNKE-------NV--A --SRVCYTF---DD--------SGKVR---MLKKTG---EIID-MGQKIHPTGFRLG--IT-QDHWSRWFA------DTD R--YPELLQEDFKVRNYV--NKNLS-----NAGIAGVRIERKA-D-QIDLEVRTARPGVVVGRGGSGIESLRVGLQKEIR INVVEVAR---VDAEATLIAEYIVQQLVRRVSFRRVVRQAIQRAQRA-GVEGIKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRANIDYSYRTASTTYGILGVKVWVFMAANDTIGDMLTRIRNANLARHQTTQV-MSTRMTRSVASVLKDEGFITSFE ESG----E---G----VERRLVITLKYR--GKNR-------Q---PIINTLQRISKPGLRVYSNRRDLPRVLGGIGIAII STSSGIMTDRDARQTGVGGEVLCYVWMQQQKIRIRLKAFDHRLLDTSCDKIVETAKRTNASPVGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHRRIVDIYQPSPKTIDALMKLDLPAGVDIEVKLIKERIGVVVSDKMDKTVVVAVSNRVPHKKYG KIVGQTRRYKAHDEE--NACHVGDRVRIRESRPLSRTKRWAVTDVLVAA------------------------------- -MSRSL-KKGPFVAD-HLLTKVENLNE---KGEKQ----VIKTWSRASTIIPQMIGHTIAVHNGRQHVPVYVSE-QMVGH KLGEFAPTRTFKSHS------K--GDK----KAR------M- >Arthrospira_maxima_CS-328 Concatenation of 16 sequences MAIRSYRPYTPSTRQHTVSEFTE-ITRS------------EP-EKSLTVSKHRLKGRNNRGVITCRH-RGGGHKKL---- YRIIDFR-R--DK-HNVPAKVAEIEYDPNRNARIALLNYV-DGEKRYILHPVGLAVGTVVISGP-D-AP-IEVGNALPLS HIPLGTSIHNVEMIPGKGGQMVRAAGASAQIMAK--EGDYVTLKLPSGEQRKIPARCYATIGQVGNVDARNISIGKAGRN -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NKKKRST-A-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFDAETGK---------AIPVTVVQAGPCT ITQVK----TEA----T--DGY--TAIQLGY-------GE--YLSH----------AEQGHLT----------------- ---SN-SPLVRHLKEYRL--------ESTDNF-----EL---GQ-EIKV--D-T-FELGQMVDVTGISMGRGFAGNQKRN NFRR-GPMAHGS-KNHR-LPGSIG-PGTTPG-RVYPGKKMAGRYGGKQITTRKLTIVRIDLERN---------------- ----------LLLIKGS-IPGKPGGLLNIK--MVDCVI-RNWEGEEVGQTTLELKVA----KE-EN-ASHIVHRALVRQQ AAARQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSVKMNRKERRLALRTAFQSRAED-------------------IVVVEEF--VTQLP-R------ --PKTKLLV--LPEKQ--E---NVYLSGRNVAKIR-I---------------CLADSLNVYDVLAADK----IVTTANAL AKIQETMTSIYQETI----VPKLMEQFKYENIHQVPKVVKVTINRGLG-EASQNAKALESSVNELAIITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFMERLIHLALPRIRDFRGISP-KSFDGRGNYSLGVKEQLIFPEID-----YDRI DQIRGLDISIVTT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--RPIPIPAKVTLT-L--- -D-G--Q-KVTVKGPKGELSRVL--PN-E--VILSLEE-DT--LIV---KR-R--DESRVAR-QRHGLCRTLVANMVDGV SQGFERRLEIQGVGY--RAQVQG-KN--LILN--VGYSKPVEMVP-P-E-GCSVAVE--N-NTNVIVSG-INKELVGNMA AKIRAVR------PPEPY---KGKGIRYAGEQVRRKAGK----------MIQQQSILNVADNSGARKLMCIRVLGGGNRR Y--GTIGDVIIAVVKDAIPN-M-------AVKKSDVVRAVIVRSRQGLRRDSGMSIRFDDNAAVIIN-QDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--QDAKPKAGS-QKRRRRLG-RGVSAGQ-GASCGKGMRGQKSRSG---G--S TRPGF-E-GGQNPLYRRLPKLKS--FPLINVGRLVTLSSLIAA-GIITLK---------ILG--DGE-L-N-V-A-LQV- KAAAFTQSARSKIEAAGGSCEKFRKQQR--GRM---RGQA-TRGNNINFG----------DFALQAL--EPSWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMFEI--AG-- VSEEVAREAMRLASFKLPIKTKF-LRNDSRQRRHRRVRRKV---LGTSERPRLAVFRSHKHIYVQVIDD---S--QQHTL VAASTL-DPEI-TADL----KTG-ATCDASVKVGQLIAKR--SYLKE--------------------------------- ---------------------------------------------------------------MS---AIARYIRMSPSK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACTPVLKVLRSAVAN----A- EHNQ-GLDPATLIVSQAFADAGPSLKRYRPRAQGRAYPIRKPTCHITVTVAEKMHVKKGDTVQVIAGR------DK-GKV GEVISTLPKLS--KVV--VKDVNVRTKHVK----PQ--QE-GEG-GRIVNFEAPIHSSNVM-LYSTKE-------KV--A --SRISYTF---TE--------DGKVR---MLKKTG---EVID-MGQKIHPIGFRLG--VT-QEHKSRWFA------DAS Q--YPQLLQEDHTIRKYI--QKNLS-----NAGISDVRIERKA-D-QIDLEVLTARPGVVVGRGGAGIDSLRQGLQKEIR INVVEVSR---VDADATLIAENIAAQLEKRVSFRRVVRQAITRAQKA-GIEGIKIQVSGRLNGAEIARTEWTREVVFPY- -----------------------------MATNDTIADMLTRIRNSCMARHQTTEI-PSTKMTRSIAKVLQDEGFIANFE EAG----V---G----VKKHLVVSLKYN--TKTR-------T---PTIRTLKRVSRPGLRVYKNRKELPRVLGGIGIAII STSRGVMTDREARLQGLGGEVLCYVWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATALGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSNKMQKTVVVAIENRSPHPKYG KIVVNTKRYKAHDED--NTCQEGDRVRIRETRPLSRTKRWNVVEIINKN------------------------------- -MSRSL-KKGPFVAD-HLLVKIEKLNA---DNRKE----VIKTWSRSSTIVPQMVGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >Arthrospira_platensis_NIES-39 Concatenation of 16 sequences MAIRFYRPYTPSTRQHTVSEFTE-ITRS------------EP-EKSLTLSKHRLKGRNNRGVITCRH-RGGGHKKL---- YRIVDFR-R--DK-HNVPAKVAEIEYDPNRNARIALLNYV-DGEKRYILHPVGLAVGTVIVSGP-D-AP-IEVGNALPLS KIPLGTSIHNVEMIPGKGGQMVRAAGASAQVMAK--EGDYVTLKLPSGEQRKIPARCYATIGQVGNVDARNISIGKAGRN -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NKKKRST-A-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFDTETGK---------AIPVTVVQAGPCT ITQVK----TEA----T--DGY--TAIQLGY-------GE--YLSH----------AEQGHLT----------------- ---SN-SPLVRHLKEYRL--------ESTDNF-----EL---GQ-EVKV--D-A-FEPGQIVDVTGISMGRGFAGNQKRN NFRR-GPMAHGS-KNHR-LPGSIG-PGTTPG-RVYPGKKMAGRYGGKQITTRKLTIVRVDLERN---------------- ----------LLLIKGS-IPGKTGGLLNIK--MVDCII-RNWDGEEVGQTTLELKVA----KE-EN-ASHIVHRALVRQQ AAARQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSVKMNRKERRLALRTAFQSRVDD-------------------IVVVEEF--VTQLP-R------ --PKTKLLV--LPEKQ--E---NVYLSGRNVEKMR-I---------------CLADSLNVYDVLAADK----IVTTANAL AKIQEPLKTTYQETI----VPKLMEQFKYENIHQVPKVVKVTINRGLG-EASQNAKALESSVNELAIITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFMERLIHLALPRIRDFRGISP-KSFDGRGNYSLGVKEQLIFPEID-----YDRI DQIRGLDISIVTT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--RPIPIPAKVTLT-L--- -D-G--Q-KVTVKGPKGELSRVL--PN-E--VILSLEG-DT--LIV---KR-R--DESLVAR-QRHGLCRTLVANMVDGV SQGFERRLEIQGVGY--RAQVQG-KN--LILN--VGYSKPVEMVP-P-E-GCSVAVE--N-NTNVIVSG-INKELVGNMA AKIRAVR------PPEPY---KGKGIRYAGEQVRRKAGK----------MIQQQSILNVADNSGARKLMCIRVLGGGNRR Y--GTIGDVIIAVVKDAIPN-M-------TVKKSDVVRAVIVRSRQGLRRDSGMSIRFDDNAAVIIN-QDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--QDAKPKAGS-QKRRRRLG-RGVSAGQ-GASCGKGMRGQKSRSG---G--S TRPGF-E-GGQNPLYRRLPKLKS--FPLINVGRLVTLSSLIAA-GIITLK---------ILG--DGE-L-N-V-A-LQV- KAAAFTQSARSKIEAAGGSCEKFRKQQR--GRM---RGQA-TRGNNINFG----------DFALQAL--EPSWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMFEI--AG-- VSEEVAREAMRLASFKLPIKTKF-LRNDSRQRRHRRVRRKV---LGTSERPRLAVFRSHKHIYVQVIDD---S--QQHTL VAASTL-DPEI-TADL----KTG-ATCDASVKVGQLIAQR--SLSKG-IERVVFDRGGYIYH--GRVKALADAAREAGLE F--------------------------------------------------------------MA-VKAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACTPVLKVLRSAVAN----A- EHNQ-GLDPATLIVSQAFADAGPSLKRYRPRAQGRAYPIRKPTCHITVTVAPKMHVKKGDTVQVIAGR------DK-GKV GEVISTLPKLS--KVV--VRDVNVRTKHVK----PQ--QE-GEG-GRIVNFEAPIHSSNVM-LYSTKE-------KV--A --SRVSYTF---TE--------DGKVR---MLKKTG---EVID-MGQKIHPIGFRLG--VT-QEHKSRWFA------DAG Q--YPQLLQEDYTIRQYI--QKNLS-----NAGISDVRIERKA-D-QIDLEVLTARPGVVVGRGGTGIDSLRQGLQKEIR INVVEVSR---VDADATLIAENIAAQLEKRVSFRRVVRQAITRAQKA-GIEGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYCTALTIYGILGVKVWVFMATNDTIADMLTRIRNSCMARHQTTEI-PSTKMTRSIAKVLQDEGFIANFE EAG----A---G----VKKHLVVSLKYN--TKTR-------T---PTIRTLKRVSRPGLRVYKNRKELPRVLGGIGIAII STSRGVMTDREARLQGLGGEVLCYVWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATALGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSNKMQKTVVVAIENRSPHPKYG KIVVNTKRYKAHDEE--NTCQEGDRVRIRETRPLSRTKRWNVVEIINKT------------------------------- -MSRSL-KKGPFVAD-HLLVKIEKLNA---DNRKE----VIKTWSRSSTIVPQMVGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >Arthrospira_platensis_str._Paraca Concatenation of 16 sequences MAIRFYRPYTPSTRQHTVSEFTE-ITRS------------EP-EKSLTLSKHRLKGRNNRGVITCRH-RGGGHKKL---- YRIVDFR-R--DK-HNVPAKVAEIEYDPNRNARIALLNYV-DGEKRYILHPVGLAVGTVIVSGP-D-AP-IEVGNALPLS KIPLGTSIHNVEMIPGKGGQMVRAAGASAQVMAK--EGDYVTLKLPSGEQRKIPARCYATIGQVGNVDARNISIGKAGRN -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NKKKRST-A-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFDTETGK---------AIPVTVVQAGPCT ITQVK----TEA----T--DGY--TAIQLGY-------GE--YLSH----------AEQGHLT----------------- ---SN-SPLVRHLKEYRL--------ESTDNF-----EL---GQ-QVKV--D-A-FEPGQIVDVTGISMGRGFAGNQKRN NFRR-GPMAHGS-KNHR-LPGSIG-PGTTPG-RVYPGKKMAGRYGGKQITTRKLTIVRVDLERN---------------- ----------LLLIKGS-IPGKTGGLLNIK--MVDCII-RNWDGEEVGQTTLELKVA----KE-EN-ASHIVHRALVRQQ AAARQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSVKMNRKERRLALRTAFQSRVDD-------------------IVVVEEF--VTQLP-R------ --PKTKLLV--LPEKQ--E---NVYLSGRNVEKMR-I---------------CLADSLNVYDVLAADK----IVTTANAL AKIQEPLKTTYQETI----VPKLMEQFKYENIHQVPKVVKVTINRGLG-EASQNAKALESSVNELAIITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFMERLIHLALPRIRDFRGISP-KSFDGRGNYSLGVKEQLIFPEID-----YDRI DQIRGLDISIVTT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--RPIPIPAKVTLT-L--- -D-G--Q-KVTVKGPKGELSRVL--PN-E--VILSLEG-DT--LIV---KR-R--DESLVAR-QRHGLCRTLVANMVDGV SQGFERRLEIQGVGY--RAQVQG-KN--LILN--VGYSKPVEMVP-P-E-GCSVAVE--N-NTNVIVSG-INKELVGNMA AKIRAVR------PPEPY---KGKGIRYAGEQVRRKAGK----------MIQQQSILNVADNSGARKLMCIRVLGGGNRR Y--GTIGDVIIAVVKDAIPN-M-------TVKKSDVVRAVIVRSRQGLRRDSGMSIRFDDNAAVIIN-QDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--QDAKPKAGS-QKRRRRLG-RGVSAGQ-GASCGKGMRGQKSRSG---G--S TRPGF-E-GGQNPLYRRLPKLKS--FPLINVGRLVTLSSLIAA-GIITLK---------ILG--DGE-L-N-V-A-LQV- KAAAFTQSARSKIEAAGGSCEKFRKQQR--GRM---RGQA-TRGNNINFG----------DFALQAL--EPSWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMFEI--AG-- VSEEVAREAMRLASFKLPIKTKF-LRNDSRQRRHRRVRRKV---LGTSERPRLAVFRSHKHIYVQVIDD---S--QQHTL VAASTL-DPEI-TADL----KTG-ATCDASVKVGQLIAQR--SLSKG-IERVVFDRGGYIYH--GRVKALADAAREAGLE F--------------------------------------------------------------MA-VKAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACTPVLKVLRSAVAN----A- EHNQ-GLDPATLIVSQAFADAGPSLKRYRPRAQGRAYPIRKPTCHITVTVAPKMHVKKGDTVQVIAGR------DK-GKV GEVISTLPKLS--KVV--VRDVNVRTKHVK----PQ--QE-GEG-GSIVNFEAPIHSSNVM-LYSTKE-------KV--A --SRVSYTF---TE--------DGKVR---MLKKTG---EVID-MGQKIHPIGFRLG--VT-QEHKSRWFA------DAG Q--YPQLLQEDYTIRQYI--QKNLS-----NAGISDVRIERKA-D-QIDLEVLTARPGVVVGRGGTGIDSLRQGLQKEIR INVVEVSR---VDADATLIAENIAAQLEKRVSFRRVVRQAITRAQKA-GIEGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYCTALTIYGILGVKVWVFMATNDTIADMLTRIRNSCMARHQTTEI-PSTKMTRSIAKVLQDEGFIANFE EAG----A---G----VKKHLVVSLKYN--TKTR-------T---PTIRTLKRVSRPGLRVYKNRKELPRVLGGIGIAII STSRGVMTDREARLQGLGGEVLCYVWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATALGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSNKMQKTVVVAIENRSPHPKYG KIVVNTKRYKAHDEE--NTCQEGDRVRIRETRPLSRTKRWNVVEIINKT------------------------------- -MSRSL-KKGPFVAD-HLLVKIEKLNA---DNRKE----VIKTWSRSSTIVPQMVGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >Arthrospira_sp._PCC_8005 Concatenation of 16 sequences MAIRSYRPYTPSTRQHTVSEFTE-ITRS------------EP-EKSLTVSKHRLKGRNNRGVITCRH-RGGGHKKL---- YRIIDFR-R--DK-HNVPAKVAEIEYDPNRNARIALLNYV-DGEKRYILHPVGLAVGTVVISGP-D-AP-IEVGNALPLS HIPLGTSIHNVEMIPGKGGQMVRAAGASAQIMAK--EGDYVTLKLPSGEQRKIPARCYATIGQVGNVDARNISIGKAGRN -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NKKKRST-A-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFDAETGK---------AIPVTVVQAGPCT ITQVK----TEA----T--DGY--TAIQLGY-------GE--YLSH----------AEQGHLT----------------- ---SN-SPLVRHLKEYRL--------ESTDNF-----EL---GQ-EIKV--D-T-FELGQMVDVTGISMGRGFAGNQKRN NFRR-GPMAHGS-KNHR-LPGSIG-PGTTPG-RVYPGKKMAGRYGGKQITTRKLTIVRIDLERN---------------- ----------LLLIKGS-IPGKPGGLLNIK--MVDCVI-RNWEGEEVGQTTLELKVA----KE-EN-ASHIVHRALVRQQ AAARQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSVKMNRKERRLALRTAFQSRAED-------------------IVVVEEF--VTQLP-R------ --PKTKLLV--LPEKQ--E---NVYLSGRNVAKIR-I---------------CLADSLNVYDVLAADK----IVTTANAL AKIQEPLKTIYQETI----VPKLMEQFKYENIHQVPKVVKVTINRGLG-EASQNAKALESSVNELAIITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFMERLIHLALPRIRDFRGISP-KSFDGRGNYSLGVKEQLIFPEID-----YDRI DQIRGLDISIVTT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--RPIPIPAKVTLT-L--- -D-G--Q-KVTVKGPKGELSRVL--PN-E--VILSLEE-DT--LIV---KR-R--DESRVAR-QRHGLCRTLVANMVDGV SQGFERRLEIQGVGY--RAQVQG-KN--LILN--VGYSKPVEMVP-P-E-GCSVAVE--N-NTNVIVSG-INKELVGNMA AKIRAVR------PPEPY---KGKGIRYAGEQVRRKAGK----------MIQQQSILNVADNSGARKLMCIRVLGGGNRR Y--GTIGDVIIAVVKDAIPN-M-------AVKKSDVVRAVIVRSRQGLRRDSGMSIRFDDNAAVIIN-QDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--QDAKPKAGS-QKRRRRLG-RGVSAGQ-GASCGKGMRGQKSRSG---G--S TRPGF-E-GGQNPLYRRLPKLKS--FPLINVGRLVTLSSLIAA-GIITLK---------ILG--DGE-L-N-V-A-LQV- KAAAFTQSARSKIEAAGGSCEKFRKQQR--GRM---RGQA-TRGNNINFG----------DFALQAL--EPSWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMFEI--AG-- VSEEVAREAMRLASFKLPIKTKF-LRNDSRQRRHRRVRRKV---LGTSERPRLAVFRSHKHIYVQVIDD---S--QQHTL VAASTL-DPEI-TADL----KTG-ATCDASVKVGQLIAKR--SLSKG-IERVVFDRGGYIYH--GRVKALADAAREAGLE F--------------------------------------------------------------MA--KAIARYIRMSPSK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACTPVLKVLRSAVAN----A- EHNQ-GLDPATLIVSQAFADAGPSLKRYRPRAQGRAYPIRKPTCHITVTVAEKMHVKKGDTVQVIAGR------DK-GKV GEVISTLPKLS--KVV--VKDVNVRTKHVK----PQ--QE-GEG-GRIVNFEAPIHSSNVM-LYSTKE-------KV--A --SRISYTF---TE--------DGKVR---MLKKTG---EVID-MGQKIHPIGFRLG--VT-QEHKSRWFA------DAS Q--YPQLLQEDHTIRKYI--QKNLS-----NAGISDVRIERKA-D-QIDLEVLTARPGVVVGRGGAGIDSLRQGLQKEIR INVVEVSR---VDADATLIAENIAAQLEKRVSFRRVVRQAITRAQKA-GIEGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYCTALTIYGILGVKVWVFMATNDTIADMLTRIRNSCMARHQTTEI-PSTKMTRSIAKVLQDEGFIANFE EAG----V---G----VKKHLVVSLKYN--TKTR-------T---PTIRTLKRVSRPGLRVYKNRKELPRVLGGIGIAII STSRGVMTDREARLQGLGGEVLCYVWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATALGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSNKMQKTVVVAIENRSPHPKYG KIVVNTKRYKAHDED--NTCQEGDRVRIRETRPLSRTKRWNVVEIINKN------------------------------- -MSRSL-KKGPFVAD-HLLVKIEKLNA---DNRKE----VIKTWSRSSTIVPQMVGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >Crocosphaera_watsonii_WH_0003 Concatenation of 16 sequences MGIRTYRPYTPGTRQAAVSDFSE-ITKS------------KP-EKSLTKYKHNKKGRNNRGVITSRH-RGGGHKRL---- YRIIDFK-R--NK-YDIPATVTSIEYDPNRNARIALLIYE-DGEKRYILAPAGIQVGTEVISGE-N-SP-FEIGNALPLY KIPLGTEVHNVELIAGKGGQMVRAAGAAAQVVAK--EGNYVTLRLPSKEVRMVRKECYATIGRVGNIEARNIKLGKAGRS -RHR-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--VGRSGPMTP---WGKPALGAKTR-NKKKASS-R-LIVRRR -----------------------------------------------MTQIFEEESGL---------AIPVTVVQAGPCT ITQIK----TTE----T--DGY--SAVQLGY-------LE--ALTK----------PELGHLK----------------- ---VN-ASPLRHLKEYRV--------EDTASY-----QL---GE-AVKA--D-I-FSTGDLVDVSGTSMGRGFAGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVYPGKKMAGQYGAAKTTTRKLTVVRVDTERN---------------- ----------LLLIKGA-VPGKPGGLLNIT--MVDCNV-KNWQGEEVGQATLELKVA----KE-ES-ASHLLHRAVVRHL ANARQGNASSKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFSKKMNRKERRLALRTAIASRVED-------------------MIVVENF--TEQLP-Q------ --PKTKLVL--LEAG---D---NIYLSARNLCFVK-I---------------LRADSLNVYDLLNADK----IVITSESL SKIQERLKIFYQETI----VPKLQQQFSYTNIHQVPKVIKITVNRGLG-EASQNAKALESSISELETITGQKPVVTRAKK AIAGFKIREGMPVGVMVTLRSEKMYAFLDRLINLALPRIRDFRGISP-KSFDGRGNYSLGVREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------ANSDEEGRALLKEMGMPFRSRIG-K--KPIPLPNKVTID-I--- -K-G--Q-HIAVKGPKGSLELDL--PS-K--VSVKQEG-EN--VVV---TT-D--DDSRTAR-ERHGLSRTLVANMVEGV SKGFEKRLSIQGVGY--RAQAQG-TK--LTLN--VGYSNPVEMTM-P-K-GVNVKVE--N-NTMVTVSG-INKEVVGNTA ATIRAVR------PPEPY---KGKGIRYVDEFVRRKAGK-----------------------------MCLRVLGTGNCT Y--GKIGDKIIAVVKDALPN-M-------PVKRSEIVTAVIVRTRQPVNRASGMTIRFDDNAAVIIN-ADGN-PRGTRVF GPVARELR-DKSYTKIVSLAPEVLMR-I--HEVTPQKGS-TKRRRRIG-RGISAGQ-GASGGFGMRGQKSRSG---T--G TKAGF-E-GGQMPLYRRVPKLKH--FPLINVSKLVTLESLMEV-GLITLK---------VLG--NGE-L-S-V-A-LTV- KAAGFTKSAKAKIEAAGGSCQKFRKQQR--GRM---RGLA-RRGSTLNFG----------DYGLQAT--EPCWITSRQIE AARRAMTRYI------KRGGKVWIRIFPDKPVTMRAAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--SG-- VEEPVAREAMRLAAQKLPIKTKF-VRRESLKRRHRRIRKKV---SGTPDCPRLAVFRSNHHIYAQIIDD---V--AQHTL AAASTL-DPDL-KKSV----SSG-ATCEASAAVGKLVAER--GKAKG-IEQVVFDRGGNIYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MA--KAIARYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPILKLLRSAVAN----A- EHNQ-GLDPGSLVVSKAYADGGPGLRRYRPRAQGRAYQIRKPTCHITIAVAPKMHVKKGDTIQVISGR------DK-GKV GEITQTLPKTG--QVV--VKGVNVRTKHVK----PQ--QE-GES-GQISTFEAPIHSSNVM-LYSTKE-------QV--A --SRISYTF---TE--------EGKVR---MLKKTG---EIID-MGQKIHPIGFRLG--IT-KEHKSCWYA------DKR R--YPELLQEDLVVREYI--EKNLS-----NAGIADIRIERKA-D-QIDLAIHTARPGVVVGRGGSGIEQLRTGLQKAIR INVIEVAR---VDADAALIAEYIGQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVGGRLNGAEIARSEWVREGRVPL- -HTLRADIDYCYRTAQTIYGILGIKVWIFMATNDTISDMLTRIRNACAVRHPTTIV-PTTRMTRSIAKVLQEEGFIEGFE EAG----E---G----VKKHLVISLKYK--SRGR-------Q---PIINTLKRVSKPGLRVYSNRKDLPRVLGGIGIAII STSKGIMTDREARRQNVGGEVLCYVWMAQQKIRIRLKAFDRRLLDTSCEKIVDTANRTDATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKERVGVVVSTKMDKTAVVAVENRSPHPKYR KIVVKTKKFKAHDPE--NKCQEGDRVRIRETRPLSKTKRWEIKDILTAH------------------------------- -MSRSL-KKGPFIAD-SLLSKIEKLNE---KGDKQ----VIKTWSRASTIIPAMIGHTIAVHNGRQHVPIFISE-QMVGH KLGEFAPTRTFRGHS------K--SDK----KAR------R- >Crocosphaera_watsonii_WH_8501 Concatenation of 16 sequences MGIRTYRPYTPGTRQAAVSDFSE-ITKS------------KP-EKSLTKYKHNKKGRNNRGVITSRH-RGGGHKRL---- YRIIDFK-R--NK-YDIPATVTSIEYDPNRNARIALLIYE-DGEKRYILAPAGIQVGTEVISGE-N-SP-FEIGNALPLY KIPLGTEVHNVELIAGKGGQMVRAAGAAAQVVAK--EGNYVTLRLPSKEVRMVRKECYATIGRVGNIEARNIKLGKAGRS -RHR-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--VGRSGPMTP---WGKPALGAKTR-NKKKASS-R-LIVRRR --------------------------------MSV---G-LLGTKLGMTQIFEEESGL---------AIPVTVVQAGPCT ITQIK----TTE----T--DGY--SAVQLGY-------LE--ALTK----------PELGHLK----------------- ---VN-ASPLRHLKEYRV--------EDTASY-----QL---GE-AVKA--D-I-FSTGDLVDVSGTSMGRGFAGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVYPGKKMAGQYGAAKTTTRKLTVVRVDTERN---------------- ----------LLLIKGA-VPGKPGGLLNIT--MVDCNV-KNWQGEEVGQATLELKVA----KE-ES-ASHLLHRAVVRHL ANARQGNASSKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFSKKMNRKERRLALRTAIASRVED-------------------MIVVENF--TEQLP-Q------ --PKTKLVL--LEAG---D---NIYLSARNLCFVK-I---------------LRADSLNVYDLLNADK----IVITSESL SKIQERLKIFYQETI----VPKLQQQFSYTNIHQVPKVIKITVNRGLG-EASQNAKALESSISELETITGQKPVVTRAKK AIAGFKIREGMPVGVMVTLRSEKMYAFLDRLINLALPRIRDFRGISP-KSFDGRGNYSLGVREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------ANSDEEGRALLKEMGMPFRSRIG-K--KPIPLPNKVTID-I--- -K-G--Q-HIAVKGPKGSLELDL--PS-K--VSVKQEG-EN--VVV---TT-D--DDSRTAR-ERHGLSRTLVANMVEGV SKGFEKRLSIQGVGY--RAQAQG-TK--LTLN--VGYSNPVEMTM-P-K-GVNVKVE--N-NTMVTVSG-INKEVVGNTA ATIRAVR------PPEPY---KGKGIRYVDEFVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GKIGDKIIAVVKDALPN-M-------PVKRSEIVTAVIVRTRQPVNRASGMTIRFDDNAAVIIN-ADGN-PRGTRVF GPVARD------------------MR-I--HEVTPQKGS-TKRRRRIG-RGISGGQ-GASGGFGMRGQKSRSG---T--G TKAGF-E-GGQMPLYRRVPKLKH--FPLINVSKLVTLESLMEV-GLITLK---------VLG--NGE-L-S-I-A-LTV- KAAGFTKSAKAKIEAAGGSCQKFRKQQR--GRM---RGLA-RRGSTLNFG----------DYGLQAT--EPCWITSRQIE AARRAMTRYI------KRGGKVWIRIFPDKPVTMRAAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--SG-- VEEPVAREAMRLAAQKLPIKTKF-VRRESLKRRHRRIRKKV---SGTPDCPRLAVFRSNHHIYAQIIDD---V--AQHTL AAASTL-DPDL-KKSV----SSG-ATCEASAAVGKLVAER--GKAKG-IEQVVFDRGGNIYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MA--KAIARYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPILKLLRSAVAN----A- EHNQ-GLDPGSLVVSKAYADGGPGLRRYRPRAQGRAYQIRKPTCHITIAVAPKMHVKKGDTIQVISGR------DK-GKV GEITQTLPKTG--QVV--VKGVNVRTKHVK----PQ--QE-GES-GQISTFEAPIHSSNVM-LYSTKE-------QV--A --SRISYTF---TE--------EGKVR---MLKKTG---EIID-MGQKIHPIGFRLG--IT-KEHKSCWYA------DKK R--YPELLQEDLVVREYI--EKNLS-----NAGIADIRIERKA-D-QIDLAIHTARPGVVVGRGGSGIEQLRTGLQKAIR INVIEVAR---VDADAALIAEYIGQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVGGRLNGAEIARSEWVREGRVPL- -HTLRADIDYCYRTAQTIYGILGIKVWIFMATNDTISDMLTRIRNACAVRHPTTIV-PTTRMTRSIAKVLQEEGFIEGFE EAG----E---G----VKKHLVISLKYK--SRGR-------Q---PIINTLKRVSKPGLRVYSNRKDLPRVLGGIGIAII STSKGIMTDREARRQNVGGEVLCYVWMAQQKIRIRLKAFDRRLLDTSCEKIVDTANRTDATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKERVGVVVSTKMDKTAVVAVENRSPHPKYR KIVVKTKKFKAHDPE--NKCQEGDRVRIRETRPLSKTKRWEIKDILTAH------------------------------- -MSRSL-KKGPFIAD-SLLSKIEKLNE---KGDKQ----VIKTWSRASTIIPAMIGHTIAVHNGRQHVPIFISE-QMVGH KLGEFAPTRTFRGHS------K--SDK----KAR------R- >Cyanobacterium_UCYN-A Concatenation of 16 sequences MGIRSYRPYTPGTRQATVSDFAE-ITKR------------KP-EKSLTKYKHNKKGRNNRGVITSRH-RGGGHKRL---- YRIIDFR-R--DK-YDIPAKVVAIEYDPNRNARLALLFYQ-DGEKRYILAPLGVTVGATLISGE-N-SP-YEIGNALPLH KIPLGSEVHNVELVPGKGGQMVRSAGAVAQLVAK--DGNYVTLKLPSKEVRMVRRECYATMGRVGNIEARNITLGKAGRT -RHL-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGAKTR-NKNKASS-R-LIIRRR --------------------------------MAI---G-LLGTKLGMTQIFDDETGA---------AIPVTVMKVGPCT ITQIK----TSD----T--DGY--NAIQIGY-------SE--ALVK----------PELGHLK----------------- ---AG-ASPLRHLKEYRV--------DDIQPY-----QL---GE-TVNV--D-L-FNTGDLVDVTGTSMGRGFAGYQKRH NFKR-GNMTHGS-KSHR-LPGSTG-AGTTPG-RVYPGKKMAGQYGASKVTTRRLKVVQIDAECN---------------- ----------LLLIKGA-IPGKPGGLLNIT--MVDCNV-KNWQGELVGQVTLNLKVA----KE-ES-SAHLLHRAVVRHL ANARQGNACSKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFSLKMNRKERRLALRTAISSRIED-------------------LIIVKDF--IEQFP-D------ --PKTKLIL--LETD---N---NIYLSVRNLSYVK-I---------------LRADSLNIYDLLNADK----IVMTSEAL VKIQERLKTIYQETI----VVKLKQQFNYTNVHQVPKVLKVNINRGLG-EASQNAKALESSIREFEIITGQKPIITRAKT AIAGFKIREGMPVGVMVTLRSEKMYSFLDRLINIALPRIRDFRGISP-KSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--RPITLPDKVTID-I--- -K-G--Q-YITVKGPKGSLEREL--PS-R--VQLNKEG-ET--LMV---QR-Q--DDSLISR-ERHGLCRTLVANMVHGV SAGFEKRLSIQGVGY--RAQAKG-TK--LTLN--VGYSKPVEIAM-P-N-GINVAVE--N-NTLVIISG-IDKEIVGNIA AKIRAVR------PPEPY---KGKGIRYLNEFVVRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCR Y--GAIGDQIVAVVKDAIPN-M-------PVKRSDIVKAVIVRTRQAINRENGMSIRFDDNAAVIIN-PDGN-PKGTRVF GPVARELR-DKSYTKIVSLAPEVLMR-I--HNLSPQEGS-TKRRRRVG-RGISAGQ-GASGGFGMRGQKSRSG---T--G TKAGF-E-GGQMPLYRRVPKLKH--FPLINVSKLVDLDSLMQQ-RIVTLK---------ILG--DGE-L-N-V-A-LMV- KAAAFTKSAQRKIESAGGSCQKFRKQQR--GRM---RGLA-YRGSTLNFG----------EYALQAI--EPCWITARQIE AARRAMTRYI------RRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--SG-- VTEPIAREAMRLAAQKLPIKTKF-IRRESLKRRHQRIRKKV---SGTSNCPRLAVFRSNQHIYAQIIDD---I--KQHTL AAASTL-EPGL-KEAA----ASS-SSCEASSAVGKLVAER--LIAKG-IEQVVFDRGGNLYH--GRVKALAEAAREAGLK F--------------------------------------------------------------MA--KAISKYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYKACEPIIKLLRSAVAN----A- EHNK-GLDPATLFISKAYADGGPSLKRFRPRAQGRAYQIRKPTCHITIAVASKMHVKVGDNIQVISGK------DK-GKI GEITKIFPKTS--QVI--IKGTNVKTKHVK----PQ--QE-GES-GQITTFEAPIHSSSVM-LYSSKK-------QV--A --SRINYTL---NE--------AGKVR---ILKKTG---EIID-MGQKIHPIGFRLG--IT-KEHKSRWYA------DKR R--YPELLQEDLAVRKHI--EKNLS-----NAGIADIRIERKA-D-QIDLAIHTARPGVVVGRGGSGIEQLRTALQKNIR INVIEVSR---VDADAALIAEYITQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVGGRLNGAEIARSEWVREGRVPL- -HTLRADIDYSYRTAQTTYGILGVKVWVFMAPNDTISDMLTRIRNACAVRHPTTKV-PTTRMTRSIAQVLKEEGFIQSFE EMG----E---G----VQKHLVISLKYK--ARGR-------Q---PIINTLRRVSKPGLRVYSHRKDLPRVLGGIGVAII STSKGIMTDREARRQNVGGEVLCYIWMAQQKIRIRLKAFDRRLLDTSCEKIVDTANRTDAIAVGPIPLPTKKRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKEKVGVVVSAQMDKTIVVAVENRSPHPKYG KIIVKTKKFKAHDQE--NKCQ---RRR----------------------------------------------------- -MSRSL-KKGPFISD-SLLTKIEKLNE---KGDKQ----VIRTWSRASTIVPVMIGHTIAVHNGKQHIPVFISE-QMVGH KLGEFSPTRTFRGHA------K--SDK----KSG------RR >Cyanobium_sp._PCC_7001 Concatenation of 16 sequences MAIRNYRPTTPGTRTRVASDFTE-VTGR------------GR-ERGLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRLVDFR-R--DK-HGVVAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGIEIGQQVVSGP-E-SP-IETGNALPLS AIPLGSSVHNVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRK -RWL-----GRR-P-EVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR ------------------------------------------GGRDSMSQFFD-EAGK---------SIPVTVIEAGPCR ITQIK----STG----T--DGY--NAVQLGF-------GD--LVNK----------PAQGHLA----------------- ---SG-EELLRHLKEYRV--------DSLDGL-----EL---GG-AVTV--A-A-FEPGQKVDVSGDTMGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RVYPGKRMAGRYGGKQTTTRGLVILKVDTERN---------------- ----------LLVVKGS-VPGKPGALLNIR--MAHCVI-RDWQGKEAGKADLDLKVA----KE-SS-ATDLVHRAVVRQL AHARQGTASTLTRAE--------VA-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGVVFGPK-P-RSYALAMNRKERRLALRTALMSRVED-------------------ITVVKGF--GAGLD-T------ --PKTKLVI--LDNAS--E---AVRKSVRNLEKVK-L---------------IAADQLNVFDLLHANK----LVVSEEAL AKIQESLKQRYRETI----QPKLLKDLNLSNVHEVPKVVKVTVNRGLG-EAAQNAKALEASIAELATITGQKVVVTRAKK AIAGFKIRQGMPIGVAVTLRGERMYAFLERLIHLALPRIRDFRGVSP-KSFDGRGNYTLGIREQIIFPEIS-----FDKI DAIRGMDVTIVTS-----------------------ARNDEEGRALLREMGMPFR-------------PDKVTVS-L--- -S-G--L-AVTVKGPKGELSRTL--PE-G--VSVAQEG-ST--IVV---SP-T--SESRRSR-ERHGLCRTLVANMVEGV SQGYTRKLEIVGVGY--RAAVQG-KK--LVVS--AGYSHPVEMVP-P-D-GVTFTVE--G-TTTVLVSG-ADKELVGNEA AKVRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQETFLNVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATLRRDTGNAIRFDDNAAVILG-NENN-PKGTRVF GPVARELR-ERNFTKIVSLAPEVIMS-I--QSLQANPGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FELVNVARLVNLDTLVKQ-GIVTLK---------VLG--NGD-L-S-V-K-LTV- QASAFTASARAKIEAAGGSCD---------------RGVA-TRGNTIAFG----------EFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGAD ITPEIAREAMRLAQYKLPVKTKF-LRKEQTQKRHRRLRRHL---TGTAERPRLAVFRSNNHIYAQVIDD---A--AQSTL CSASTV-DKEL-RPSV----TAA-GTCEASVAVGQLVAKR--ALAKG-ISQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MA---AHGRYIRGSVSK VRRVLDQIRGRTYREALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GMDPASLVVTTASADMGPSMKRYRPRAQGRAYAIKKQTCHISIAVAPKMRIKKGDTVQVIAGK------DK-GKT GEVLRTLPYEN--RVV--VQGINLRTRHVK----PT--QE-GET-GRIVTEEASLHASNVM-LFSTSK-------NV--A --SRVEIVV---ES--------DGKKR---RLKKTG---EILD-MGHKIHPTGLRLG--IT-QDHRSRWYA------PSK T--YPTLLQEDDRIRKFI--HKKYG-----AAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEDLRNGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRVIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKLASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTRI-PASRLLRSIATVLQQEGFIAGIS EEG----E---G----VQKHLVVELKYS--GKHR-------Q---PTIRSVQRVSKPGLRIYKNNRQLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCEKIIETADHTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERVGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTKRYKAHDED--NSCKVGDRVRITETRPLSRTKRWTVAEVLNTS------------------------------- -MGRSL-KKGPFVAD-SLLRKVEKQNA---ANDKT----VIKTWSRASTILPMMIGHTIAVHNGKSHVPVYVTE-QMVGH KLGEFAPTRTFRGHI------K---DK----KGG------R- >Cyanothece_sp._ATCC_51472 Concatenation of 16 sequences MGIRTYRPYTPGTRQASVSDFAD-ITKP------------KP-EKSLTTYKHNKKGRNNRGVITSRH-RGGGHKRL---- YRIVDFK-R--DK-YGVPAKVAAIEYDPNRNARIALLFYQ-DGEKRYILAPAGITVGTEVISGE-D-SP-FEVGNALPLY KIPLGTEVHNIELVAGKGGQMVRAAGAAAQVVAK--EGDYVTLRLPSKEVRMVRKECYATIGRVGNTEARNIKLGKAGRT -RHL-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--VGRSGPMTP---WGKPALGAKTR-NKKKASS-R-LIVRRR --------------------------------MAV---G-LLGTKLGMTQIFEEESGL---------AIPVTVVQAGPCT ITQIK----TAE----T--DGY--SAIQIGY-------LE--ALTK----------PELGHLK----------------- ---VE-ASPLRHLKEYRV--------DDTATY-----TL---GE-AVKA--D-I-FNAGDLVDIAGTSMGRGFAGYQKRH NFKR-GSMTHGS-KNHR-LPGSTG-AGTTPG-RVYPGKKMAGQYGAVKTTTRHLQVVRVDAERN---------------- ----------LLLIKGA-VPGKPGGLLNIT--MVDCNV-KNWQGEEVGQTTLELKVA----KD-ET-ASHLLHRAVVRHL ANARQGNASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFSLKMNRKERRLALRTAIGSRVED-------------------MIVVENF--AEQLP-Q------ --PKTKALV--LVETD--A---NIYLSARNLCHVK-I---------------LRADSLNVYDLLDADK----IVITSEAI SKIQERLKTFYQETI----VPKLQQQFSYSNIHQVPKIAKITINRGLG-EASQNAKALESSISELETITGQKPVVTRAKK AIAGFKIREGMPVGVMVTLRSEKMYAFLDRLINLALPRIRDFRGISP-KSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--KPIPLPNKVTID-I--- -K-G--Q-HIAVKGPKGSLELDL--PS-E--VTVNQEG-ET--VEV---QR-V--DDSRTAR-ERHGLFRTLVANMIQGV SQGFEKRLNIQGVGY--RAQAQG-SK--LTLN--VGYSKPVEMTM-P-Q-GINVAVE--N-NTQVVVSG-IDKEI----- -------------------------------------------------MIQQQTYLNVADNSGARKLMCLRVLGTGNCR Y--GEIGDKIVAVVKDALPN-M-------PIKRSDIVTAVIVRTRQPVNRASGMSIRFDDNAAVIIN-ADGN-PRGTRVF GPVARELR-DKSYTKIVSLAPEVLMR-I--HEVNPQKGS-TKRRRRIG-RGISAGQ-GASGGFGMRGQKSRSG---T--G TKAGF-E-GGQMPLYRRVPKLKH--FPLINVGKLVTLESLMEV-GLITLK---------VLG--NGE-L-T-V-P-LTV- RAPKFTASAKAKIESAGGSCQKFRKQQR--GRM---RGLA-HRGSTLNFG----------EYALQAT--EPSWITSRQIE AARRAMTRYI------KRGGKIWIRVFPDKPVTMRAAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--SG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESLKRRHRRIRRKV---SGTPDCPRLAVFRSNHHIYAQIIDD---V--AQHTL AAASTL-EPDL-RNSL----SSG-ATCEASAAVGKLVAER--GMAKG-IEQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MA--KAIARYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPILKLLRSAVAN----A- EHNQ-GLDPTTLVVSQAYADGGPSLRRYRPRAQGRAYQIRKPTCHITIAVAPKMHVKTGDTIQVISGR------DK-GKV GEVLKTIPTTS--EVV--VKGVNVKTKHVK----PQ--QE-GES-GQIATFEAPIHSSNVM-LYSTKE-------QV--A --SRISYTF---TE--------EGKVR---MLKKTG---EIIDSMGQKIHPIGFRLG--VT-KEHKSCWYA------DKR R--YPELLQEDLAIRQHV--EKNLS-----NAGIADIRIERKA-D-QIDLAIHTARPGVVVGRGGSGIEQLRTGLQQTIR INVIEVSR---VDADAALIAEYITQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVGGRLNGAEIARTEWVREGRVPL- -HTLRADIDYAYRTAQTIYGILGVKVWVFMAPNDIISDMLTRIRNACAVRHPTTVV-PTTKMTRSIAQVLKEEGFIEGFE EVG----E---G----VKKHLVISLKYK--SRGR-------Q---PIINTLQRVSKPGLRVYSNRKDLPRVLGGIGIAII STSKGIMTDREARRQNVGGEVLCYVWMAQQKIRIRLKAFDRRLLDTSCEKIVDTANRTDATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKERVGVVVSTKMDKTAVVAVENRSPHPKYG KIVVKTKKFKAHDPE--NQCQEGDRVRIRETRPLSKTKRWEIKTILTAH------------------------------- -MSRSL-KKGPFIAD-SLLTKIEKLNE---KGDKQ----VIKTWSRASTIIPAMIGHTIAVHNGKQHVPIFISE-QMVGH KLGEFAPTRTFRGHS------K--GDK----KAR------R- >Cyanothece_sp._CCY0110 Concatenation of 16 sequences MGIRTYRPYTPGTRQASVSDFAD-ITKR------------KP-EKSLTTYKHNKKGRNNRGVITSRH-RGGGHKRL---- YRIVDFK-R--DK-YGVPAKVAAIEYDPNRNARIALLFYA-DGEKRYILAPAGITVGTEVVSGE-D-SP-FEVGNALPLY KIPLGTEVHNVELVAGKGGQMVRAAGAAAQVVAK--EGDYVTLRLPSKEVRMVRKECYATIGRVGNTEARNIKLGKAGRT -RHL-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--VGRSGPMTP---WGKPALGAKTR-NKKKASS-R-LIVRRR --------------------------------MAV---G-LLGTKLGMTQIFEEESGL---------AIPVTVVQAGPCT ITQIK----TAE----T--DGY--TAIQIGY-------LE--NLTK----------PELGHLK----------------- ---AE-ASPLRHLKEYRV--------EDTASY-----TL---GE-AVKA--D-I-FNAGDLVDIAGTSMGRGFAGYQKRH NFKR-GSMTHGS-KNHR-LPGSTG-AGTTPG-RVYPGKKMAGQYGAVTTTTRHLEVVKVDAERN---------------- ----------LLLIRGA-VPGKPGGLLNIT--MVDCNV-KNWQGEEVGQATLELKVA----KD-ET-ASHLLHRAVVRHL ANARQGTASSKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFGLKMNRKERRLALRTAIGSRAED-------------------MIVVENF--AEQLP-Q------ --PKTKLVL--VETD---E---NIYLSARNICYLK-I---------------MRADSLNVYDLLDADK----IVITSEAL TKIQERLKTFYQDTI----VPKLQQQFSYSNIHQVPKVAKITINRGLG-EASQNAKALESSISELETITGQKPVVTRAKK AIAGFKIREGMPVGVMVTLRSEKMYAFLDRLINLALPRIRDFRGISP-KSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------AQTDEEGRALLKEMGMPFRSRIG-K--KPIPLPNKVTID-I--- -K-G--Q-HIAVKGPKGSLELDL--PS-Q--VTVNQDG-ET--ILV---QR-V--DDSRVAR-ERHGLFRTLVSNMIEGV SKGFEKRLSIQGVGY--RAQAQG-TK--LTLN--VGYSKPVEMTM-P-K-GINVAVE--N-NTQVVVSG-IDKEIVGNIA AKIRGVR------PPEPY---KGKGIRYQDEYVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCR Y--GEIGDKIVAVVKDALPN-M-------PIKRSDIVTAVIVRTRQPVNRASGMSIRFDDNAAVIIN-ADGN-PRGTRVF GPVARELR-DKSYTKIVSLAPEVLMR-I--HEVNPQKGS-TKRRRRIG-RGISAGQ-GASGGFGMRGQKSRSG---T--G TKAGF-E-GGQMPLYRRVPKLKH--FPLINVGKLVTLESLMEV-GLITLK---------VLG--DGE-L-T-V-A-LTV- KAAAFTKSAKAKIESAGGNCQKFRKQQR--GRM---RGLA-HRGSTLNFG----------EYALQAT--EPSWITARQIE AARRAMTRYI------KRGGKIWIRVFPDKPVTMRAAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--SG-- VSEPIAREAMRLAAQKLPIKTKF-IRKESLKRRHRRIRRKV---SGTPDCPRLAVFRSNHHIYAQIIDD---V--AQHTL AAASTL-EPDL-RNSL----SSG-ATCEASAQVGKLVAER--GMAKG-IEQVVFDRGGNLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MA--KAVARYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPILKLLRSAVAN----A- EHNQ-GLDPATLVVSKAYADGGPSLRRYRPRAQGRAYQIRKPTCHITIAVAPKMHVKKGDTIQVISGR------DK-GKV GEVIKTMPQTS--QIV--VQGVNVRTKHVK----PQ--QE-GES-GQIATFEAPIHSSNVM-LYSTKE-------QV--A --SRISYTF---TE--------EGKVR---MLKKTG---EVID-MGQKIHPIGFRLG--VT-KEHKSCWYA------DKR R--YPELLQEDLAIRQYV--EKNLS-----NAGIADIRIQRKA-D-QIDLAIHTARPGVVVGRGGSGIEQLRTGLQQTIR INVIEVSR---VDADAALIAEYITQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVGGRLNGAEIARSEWVREGRVPL- -HTLRADIDYAYRTAQTIYGILGVKVWVFMAPNDIISDMLTRIRNACAVRHPTTVV-PTTKMTRSIAKVLQEEGFIEGFE EVG----E---G----VKKHLVLSLKYK--SRGR-------Q---PIINTLQRVSKPGLRVYSNRKDLPRVLGGIGIAII STSKGIMTDREARRQNVGGEVLCYVWMAQQKIRIRLKAFDRRLLDTSCEKIVDTANRTDATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLIKERVGVVVSTKMDKTAVVAVENRSPHPKYG KIVVKTRKFKAHDPE--NQCQEGDRVRIRETRPLSKTKRWEIKTILTAH------------------------------- -MSRSL-KKGPFIAD-SLLTKIEKLNE---KGDKQ----VIKTWSRASTIIPAMIGHTIAVHNGKQHVPIFISE-QMVGH KLGEFAPTRTFRGHA------K--GDK----KAR------R- >Cyanothece_sp._PCC_7822 Concatenation of 16 sequences MGIRTFRPLTPGTRQASVSDFSE-ITKS------------TP-EKSLTQNKHSASGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-HNIPAKVAAIEYDPNRNARIALLYYQ-DGEKRYILAPADLKVGSTVISGE-D-AP-FEIGNALPLG RIPLGSDVHNIELVAGRGGQMVRAAGASAQVVAK--EGNYVTLRLPSKEVRMVRKECYATIGKVGNADVRNLKLGKAGRT -RHL-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NRKKQSS-K-LIVRRR --------------------------------MSV---G-IIGTKLGMTQIFDKETGI---------AIPVTVIHAGPCP ITQIK----TPE----T--DGY--SSIQIGY-------GE--ALNK----------PLLGHLK----------------- ---SE-SIPLKNLKEYRL--------DNPEQY-----QL---GD-ALKV--D-I-FQPGDIVDVAGKTIGRGFAGYQKRH NFKR-GSMTHGS-KNHR-LPGSTG-AGTTPG-RVYPGKRMAGRYGGTQVTIRKLTVVQVDPERN---------------- ----------LILIKGA-VPGKPGNLLSIT--MVNCVV-KNWDGDEVGQTPLELKVA----KE-ET-ASHILHRAVVRQL ANARQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---NR-SP----LW---- RGGGVIFGPK-P-RDYNLKMNRKERRLALRTALNNQAEN-------------------LIIVENF--GEQFP-Q------ --PKTRLLI--LSEIP--E---NVGLSARNICNVK-V---------------IKADSLNVYDLLTASK----LVATSDAL EKILERLKKVYQETI----VPKLTEQFGYKNIHQVPKVIKVTVNRGLG-EASQNAKALESSINELSIITGQKPVVTRAKK AIAGFKIRKGMPVGVMVTLRQERMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEID-----YDKI EQIRGMDISIITT-----------------------ARTDEEGRALLTEMGMPFRSRIG-K--RPIEIPNKVTVN-I--- -E-G--S-HVAVKGPKGELERTL--PS-M--VNVELTD-NT--LRV---VR-T--DDSRVAR-QRHGLCRTLVFNMVEGV SNGFEKRLEIQGVGY--RAAAAG-SK--LTLN--VGYSKPVEMDM-P-Q-GITVAVE--K-NTEITISG-IDKEIVGNIA AKIRAVR------PPEPY---KGKGIRYKGELVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNRR Y--GGIGDEIIAVVKDAIPN-M-------PVKKSDVVKAVIVRTRHPLRRSSGMTIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HELSPQKGA-TKRRRRVG-RGISAGQ-GASAGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPIINVGKLVSLESLMEA-GIITLK---------VLG--HGE-L-T-I-P-LTI- KAAAFSSGAKEKIEAAGGSWAKFRKQQR--GRM---KGLA-TRGSTIDFG----------DYGLQAT--EPCWITSRQIE AARRAITRYV------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEFWVAVVKP-GRIMFEI--AG-- VSEEIAREAMRLAAQKLPIKTKF-VRKESVQRRHRRIRRTV---EGSPERPRLAVFRSNKHIYAQVIDD---A--AQHTL VAASSL-DKEL-KTEL----ESG-GNCDASVAVGKLVAQR--ALAKG-ISAVVFDRGGNLYH--GRVKALAEAAREAGLD F--------------------------------------------------------------MT--KAIARYVRMSPYK VRRVLDQIRGRTYQEALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- EHNN-GLDRATLVISKAYADGGPSLRRYRARAQGRAYQIRKPTCHITISVAPTMHVKKGDTVQVISGR------DK-GKV GEVIKALPKLS--KVI--VQGVNVRTKHVK----PT--QE-GES-GQISTFEAPIHSSNVM-LYSTKE-------KV--A --SRIGYTF---TE--------DGKVR---MLKKTG---EIIDQMGQKIHPVGFRLG--IT-KEHKSRWYA------DKH N--YPELLQEDRKIRSYI--DANLS-----NAGISDVRIERKA-D-QVDIEIHTARPGVVVGRGGSGIESLRLGLQTAIR INVIEVSR---VDADATLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKVQVSGRLNGAEIARTEWIREGRVPL- -HTLRADIDFSYRTAKTIYGILGVKVWVFMASNDTIADMLTRIRNACAVRHPTTKV-PTTKMTRSIALVLKQEGFIEDFS EAG----E---G----VAKHLLISLKYK--DKNR-------Q---PIITTLKRVSKPGLRVYAPCKDLPRVLGGIGIAIV STSKGIMTDREARRQGIGGEVLCYIWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRRVYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRTRHPKYR KIVVQTKKYKAHDEE--NQCKTGDRVRIQETRPLSKTKRWIVAEILTHV------------------------------- -MSRSL-KKGPFVAD-HLLSKIEKLND---KGEKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPIYISE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >Cyanothece_sp._PCC_8802 Concatenation of 16 sequences MGIRSYRPYTPGTREASVSDFAE-ITKT------------EP-EKSLTTYKHSRQGRNNRGVITSRH-RGGGHKRL---- YRIVDFR-R--DK-HNIPAKVAAIEYDPNRNARIALLFYK-DGEKRYILAPAGITVGTMVVSGE-N-AP-FEVGNALPLA RIPLGTDVHNIELTPGKGGQMVRAAGGSAQVVAK--EGDYVTLRLPSKEVRMVRKECYATIGRVGNVEDRNIKLGKAGRT -RHL-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NKKKQSS-K-LIVRRR --------------------------------MAV---G-ILGTKLGMTQIFDQETGM---------AIPVTVVQAGPCT VTQVK----TPD----T--DGY--TAIQVGY-------HE--ALTK----------AEIGHLK----------------- ---ID-APPLRHLKEYRL--------DDSSQY-----QL---GD-AIKA--D-I-FNPGDLVDVSGKSMGRGFAGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVYPGKRMAGQYGATQVTIRHLTVVRVDSDRN---------------- ----------LILVKGA-IPGKPGTLLNIT--MVNCII-KNWQGEEVGQATLELKVA----KE-EN-AAHIVHRALVRQQ TNARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVTFGPK-P-KDFNVKMNRKERRLALRTALDSRIED-------------------LIVVENF--AEQLT-Q------ --PKTKLIV--SEIT---D---NIQLSARNVPYIK-L---------------LKADGLNVYDLLVADK----IVATAEAL SKVQERLKQVYQDTI----VPKLTEQFSYKNPHEVPKVVKITVNRGLG-EASQNAKALESSINELSTITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFLDRLINLALPRIRDFRGISA-KSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------AQTDEEGRALLKELGMPFRSRIG-K--RPIPIPNKVTID-I--- -Q-G--Q-HVAVKGPKGSLERTL--PD-K--VNVVQEN-DT--LLV---QR-E--DDSRTAR-ERHGLTRTLVANMVEGV SKGFEKRLSIQGVGY--RAQVQG-TK--LTLN--VGYSKPVEMTM-P-A-GIQVAVE--N-NTLVIVSG-IDKEIVGNVS AEIRAVR------PPEVY---KGKGIRYSDEFVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCR Y--GEIGDVIIAVVKDAIPN-M-------PIKRSEIVRAVIVRTRQPVRRASGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMR-I--HEVNPKEGS-TKRRRRVG-RGISAGQ-GASCGFGMRGQKSRSG---T--G TKAGF-E-GGQMPLYRRIPKLKH--FPLINVGKLVTLESLMEQ-GIITLK---------VLG--DGT-L-T-K-A-LTV- KAAAFSKSAQEKIAATGGSWEKFRKQQR--GRM---RGMA-YRGSTINFG----------DYALQAT--EPCWITSRQIE AARRAMTRYI------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--DG-- VSEPIAREAMRLAAQKLPIKTKF-IRKESVQRRHRRIRKKV---NGTPNCPRLAVFRSNLHIYAQIIDD---V--GQHTI AAASTV-EPDL-KKSL----SSG-STCEASAAVGKLVAER--ALAQG-IEQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MA--KAIARYIRMSPHK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAAAN----A- EHNE-GLDRATLVVSQAYADGGPSLRRYRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDTVQVISGR------DK-GKV GEVVKTDPTTS--TVV--VQGVNVRTKHVK----PQ--QE-GES-GQISTFEAPIHSSNVM-LYSTKE-------QV--A --SRVSYTF---TE--------EGKVR---MLKKTG---EIID-MGQKIHPIGFRLG--IT-ADHKSCWYA------DSK R--YPETLQEDRQIRQYI--TKNLS-----NAGISDIRIERKA-D-QVDLAIHTARPGVVVGRGGSGIEQLRLGLQQDIR INVIEVQR---VDADAMLIAEYITQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYAYRTAQTIYGILGVKVWVFMAPNDTISDMLTRIRNACAVRHPTTQV-PTTKMTRSIAQVLKEEGFIEGFE ETG----E---G----VQKYLVLTLKYK--DKNR-------Q---PIINMLKRVSKPGLRVYSNCKDLPRVLGGIGIAIV STSKGIMTDREARRQNVGGEILCYIWM-QQKIRIRLKAFDRRLLDTSCEKIVDTANRTEATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKERVGVVVSNKMDKTVVVAIENRSPHPKYG KIVVKTKKFKAHDQE--NQCQEGDRVRIQETRPLSKTKRWVVAEILTSH------------------------------- -MGRSL-KKGPFVSD-SLLTKIEKLNE---KGDKQ----VIKTWSRASTILPQMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KSR------R- >Cylindrospermopsis_raciborskii_CS-505_CS505_30 Concatenation of 16 sequences MGTRSYRPYTPSTRQVTISDFAE-ITKT------------EP-EKSLTESVHRPKGRNNQGRITSRR-RGGGHKQL---- YRIIDFK-R--DK-RDITATVIAVEYDPNRNARIALVEYE-DGEKRYILHPNGLKVGAKITAGP-Q-AP-FEDGNALPLS NIPLGTNVHNVEMTPGKGGQIVRAAGATAQLMAK--EGNYVTLKLPSGEVRMVRRECYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-KRKKASS-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQIFD-EAGV---------SIPVTVIQAGPCT VTQVK----TQP----T--DGY--CAIQVGY-------GE--ALNK----------PKLGHLA----------------- ---SS-AGPVRYLNEYRT--------DAAGDY-----AL---GQ-EIKA--D-I-FSVGQIVDVIGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHR-APGSIG-AGTTPG-RVYPGKRMAGRLGGSRVTVRKLTVVKVDAERN---------------- ----------LILIKGA-IPGKPGGLVNVV--MVESTV-KNWQGEEVGQTSFELRVA----KE-ET-ASHIVHRALVRQM TNSRQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFNIKLNRKERRLALRTAFVSRRED-------------------LIVVEEF--TDQLQ-R------ --PKSKLLI--LSEIGQNTE--TISLSARNVENIK-V---------------IAADQLNVFDLLHADK----IVVTSSAL TKIQERLKTLYGQTI----VPKLTQQFQYTNVHQVPKVLKVTVNRGLG-EAAQNAKALEASLSEIALITGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRGERMYAFLDRLISLALPRIRDFRGVSA-KSFDGRGNYTLGVREQLIFPEIE-----YDRI DQIRGLDISIITT-----------------------AKTDEEGRALLKEMGMPFRSRIG-K--RPITIPAKVQVA-I--- -D-G--T-KVVVKGPKGELSRDL--PA-H--VTVSQSG-ET--LLV---TR-R--DDTRTSR-QMHGLSRTLVANMVEGV SQGFQRRLEIQGVGY--RAQVQG-AN--LVLN--IGYSHQVQIEP-P-A-GVQFVVE--N-NTNVIVSG-YDKEVVGNTA AKIRAVR------PPEPY---KGKGIRYAGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLGAGNRR Y--GGVGDRIIAVVKDAQPN-M-------AVKKSDVVEAVIVRTKKSINRDSGMSIRFDDNAAVIIN-KEGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--NDVKPQKGS-KKRRKRVG-RGISAGQ-GASAGLGMRGQKSRSG---S--S TRPGF-E-GGQQPLYRRIPKLKG--FPVINVEKLVNLASLKEA-GILTLK---------VLG--NGE-L-G-V-P-LKV- QAAAFTGQARSKIEAAGGSCEKFRKQQR--GRM---EGLA-HRGSTLNFG----------DFALQAQ--EPCWITSRQIE ASRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEI--AG-- VSEEIAREAMRLAAYKLPIKTKF-IRRESKQRRHRRVRGKV---NGSPERPRLSVFRSNEHIYAQIIDD---T--QHCTL VAASTV-DPQL-RSDL----ASG-ANCDASAQVGKLIAAR--SLEKG-ITKVVFDRGGNLYH--GRIQALAEAAREAGLD F--------------------------------------------------------------MA--KAIARYIRVSPYK VRRVLDQIRGLSYREALIILEFM---------------------------------PYRACEPVLKVLRSAAAN----A- EHNA-GLDRASLVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITVAVGEKMHVKTGDTVQVIAGK------DK-GKV GEVIKALPQDS--RVI--VKGVNIKTKHVK----PQ--QE-GES-GRIVSQEYPIHSSNVM-LYSTKQ-------NI--A --SRVCYTF---TE--------DGKVR---MLKKTG---EILDKMGQKIHPVGFRLG--IT-QEHQSLWFA------VPG R--YPELLQEDHKLRQYI--EQKLGRNAQNNAGLSEIHIERKA-D-QVDLELRTARPGVVVGRGGQGIEALRTGLQQLVR INVVEVQK---VDADAYLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-GVQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAQTVYGILGIKVWVFMAANDTIADMLTRIRNANLARHQTTEV-PATKMTRSIAKVLQQEGFISEYT EAG----E---G----VKRNLVISLKYK--GKSR-------Q---PLITTLKRVSKPGLRVYSNKKELPRVLGGIGIAII STSSGIMTDREARRQNLGGEVLCYVWMQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIHQPSSKTIDALMKLDLPSGVDIEVKLIKERVGLVVSDKMQKTVVVAVENRSSHPKYG KTVVKTRRYKVHDAE--NSCKVGDRVRIQETRPLSKTKRWQVTEILNVK------------------------------- -MGRSL-KKGPFVAD-HLLSKIEKLNA---NNEKQ----VIKTWSRASTILPLMVGHTIAVHNGKQHVPVFVNE-QMVGH KLGEFAPTRSYRGHG------K--TDK----KSG------R- >Fischerella_sp._JSC-11 Concatenation of 16 sequences MGTRSFRPYTPSTRQVTISDFSE-ITKT------------EP-EKSLTKYVHRAKGRNNQGRITSRF-RGGGHKRL---- YRIIDFK-R--NK-RDIPAEVIAIEYDPNRNARIALLQYQ-DGEKRYILQPNGLKVGTTVIAGV-N-AP-IEDGNALPLS NIPLGTSVHNVELTPGKGGQIVRSAGATAQVVAK--EGNYVTLKLPSGEVRMIRRECYATIGQVGNIDARNLSAGKAGRN -RWK-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KPKKPSS-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQIFD-DAGV---------AIPVTVIQAGPCT VTQVK----TKQ----T--DGY--SAIQVGY-------GE--ALNK----------PLLGHLA----------------- ---SS-APALRHLKEYRL--------DNSGDY-----AL---GQ-QIKA--D-I-FSAGQQVDVIGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHR-APGSTG-AGTTPG-RVYPGKRAPGRLGGSRTTVRKLTVVRVDSERN---------------- ----------LLLVKGA-VPGKPGSLLNIL--MFECVV-KNWQGEQVGQKSFDLRVA----KE-QT-AAHIVYRALIRQM ANARQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYEIKMNRKERKLALRTAFASRVDD-------------------LIVVEEF--SEQLQ-R------ --PKTKLLV--LSEKN--E---NVLLSARNVENLK-L---------------IAADNLNVYDLLHADK----IVVTASAL EKIQERLKSLYQETI----VPNLTKQFGYTNVHQVPKLVKVTVNRGLG-EAAQNAKALEASLSEIALITGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRGERMYSFLDRLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQLIFPEVE-----YDSI DQIRGMDISIITT-----------------------AKSDEEGRALLKEMGMPFRSRIG-K--RPITVPAKVQVN-F--- -D-N--A-KVTVKGPKGELSREL--PA-N--VILSQDG-ET--LTV---SR-R--DESRTSR-QLHGLFRTLVANMVEGV SKGFERRLEIQGVGY--RAQVQG-RN--LVLN--MGYSHQVQIAP-P-E-GIQFAVE--N-NTNVIVSG-YDKELVGNTA AKIRAVR------PPEPY---KGKGIRYAGEAVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLGAGNCR Y--GFVGDRIIAVVKDAQPN-M-------AIKKSDVVEAVIVRTRHNIKRDSGMSIRFDDNAAVIIN-KDGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVLMT-L--NDVRPQKGS-KKRGRRLG-RGVSAGQ-GASAGKGMRGQKARSG---G--S TRPGF-E-GGQQPLYRRIPKLKG--FPLINVEKLVTLTSLQEA-GILTLK---------ILG--DGE-L-N-V-P-LKV- KAAAFTGTARSKIEAAGGSCEKFRKQQR--GRM---KGLA-TAGSSLNFG----------DFALQAQ--EPAWITARQIE ASRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEYWVAVVKP-GRILFEI--AG-- VPEATAREAMRLAAYKLPIKTKF-IRRESKQRRHRRIRGKV---SGSPERPRLAIFRSHQHIYAQVIDD---T--QHHTI VAASTV-EPEL-KSKLT----FG-GNIQASTEVGKLIATR--ALEKG-ITKVVFDRGGNLYH--GRVKALADAAREAGLD F--------------------------------------------------------------M---KAIARYIRMSPYK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPVLKVLRSAAAN----A- EHNE-GLDRADLVITKAYADQGPVLKRFQPRAQGRAYQIRKPTCHITVAVAPKMHVKAGDTVQVIAGK------DK-GKV GEIIKALPQES--KVI--VKGVNIKTKHVK----PQ--AE-GES-GRIVTQEYPIHSSNVM-LYSTKQ-------NV--A --SRICYTF---TE--------EGKVR---MLKKTG---EIIDKMGQKIHPVGFRLG--IT-QEHQSRWFA------DPS R--YPELLQEDHKLRNFI--EEKLGRYAQNNAGISEVRIERKA-D-QIDLEVRTARPGVVVGRGGQGIESLRTGLQDLIR INVVEVQR---VDADAYLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-GVQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYCTAKTIYGILGIKVWVFMATNDTIADMLTRIRNANLARHQTTQV-PSTKMTRNIAKVLREEGYIGDYE DVG----E---G----SKRNLVISLKYK--GKNR-------Q---PIITTLKRVSKPGLRVYSNKKELPRVLGGIGIAII STSSGIMTDREARRQNLGGEVLCYVWMQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKLVKERVGLVVSDKMQKTVVVAVENRAPHPKYG KIVVNTRRYKAHDEE--NRCKIGDRVRIQETRPLSKTKRWQVTEILTTK------------------------------- -MGRSL-KKGPFVAD-HLLSKIEKLNE---SNRKE----VIKTWSRASTILPEMVGHTIAVHNGRQHVPVFISD-QMVGH KLGEFAPTRTFRGHA------K---DK----KAG------R- >Lyngbya_sp._PCC_8106 Concatenation of 16 sequences MGIRSYRPYTPSTRQHSVSDFAE-VTRS------------TP-EPSLVTTKHRHKGRNNRGVITCRH-RGGGHKKL---- YRIIDFR-R--DK-HNIPAKVAEIEYDPNRNARIALLHYI-DGEKRYILHPVGLKVGTVITSGP-E-SA-IEVGNALPLS RIPLGTDVHNVELIPGKGGQVVRAAGASAQLMAK--EGEYVTLKLPSGEQRKIPARSYATIGQVGNIEARNISIGKAGRN -RWK-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPCTP---WGKPALGLKTR-NPKKRST-K-LIVRRR ------------------------------------------GGRQSMTQVFDAESGI---------AIPVTVIEAGPCI VTQIK----TES----T--DGY--TAIQLGY-------GE--YLSN----------AEQGHLA----------------- ---SG-GQLVRHLREYRI--------EDTSSY-----EL---GQ-ELKA--D-L-FEPGQLVDVSGISMGRGFSGFQKRH NFRR-GPMAHGS-KNHR-QPGSIG-PGTTPG-RVYPGKKMAGRYGGKKITTSKLIVVRIDPERN---------------- ----------LLLIKGA-VPGKPGGLLNIT--MADCVV-RNWEGEQVGQANLELKVA----KE-EN-AAHIVHRALVRQM NNARQGSASSKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFSQKMNRKERRLALRTALQSRIED-------------------IVVVEEF--LEQLP-R------ --PKTKLLV--LPEKQ--E---NVYLSGRNIARMR-I---------------CLADSLNVYDILHADN----IVTTAAAL EKIQEQIKNQYLEKV----VPKLMEQFGYQNIHQVPKIIKITINRGLG-EASQNAKALDSSLKEISMITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFLERLIHLALPRIRDFRGISP-KSFDGRGNYSLGVREQLIFPEIE-----YDSI DQIRGLDISIITT-----------------------AQSDEEGRALLKEMGMPFRSRIG-K--RPIPIPPKVTFT-I--- -E-G--Q-HIIVKGPKGELSRVL--PE-K--VILEQDG-DT--LLV---KR-R--DESRVAR-QLHGLSRTLVANMVDGV SKGFEKRLEIQGVGY--RAQVQG-KN--LILN--VGYSKPVEMNP-P-Q-GITVAVE--N-NTNVIISG-IDKEVVGNIA AQIRAVR------PPEPY---KGKGIRYAGEQVRRKAGK----------MIQTQTILNVADNSGARKVMCIRILGGGNRR Y--ARIGDEIIAVVKDAIPN-M-------AVKRSDVVRAVVVRTRHSLRRDSGMSIRFDDNAAVIIN-PEGN-PRGTRVF GPIARELR-EKNYMKIVSLAPEVIMR-L--EDAVPKAGS-RKRRRRLG-RGISAGQ-GASCGKGMRGQKARSG---R--G TRPGF-E-GGQNPLYRRLPKLKG--FPQINVGKLVTLDSLQKA-GILTLK---------VLG--DGE-L-N-V-P-LQV- KAAAFTQSARSKIEAAGGSCEKFRKQQR--GRM---RGQA-SRGNTISFG----------EYALQAL--EPSWITARQIE AARRAMTRYI------RRGGQIWIRIFPDKPITMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMFEL--AG-- VSEEIAREAMRLADSKLPIKTKF-IRRESRTRRHRRVRRKV---FGTSQRPRLAVFRSHKHIYAQVIDD---T--QHHTL AAASTL-DPDL-KTQV----ETG-GTCDASVQVGQLLAQR--LLSQG-ISKVVFDRGGYLYH--GRVKALAEAAREAGLD F--------------------------------------------------------------MP--KAIARYIRMSPHK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRSCQPILKALRSAVAN----A- EHNQ-GLDPATLVVSQAFADQGPSLKRYRPRAQGRAYQIRKPTCHITVAVAPKMHVKTGDTVQIIAGK------DK-GKV GEVIRAIPRLS--KVV--VKDINIRTKHVK----PQ--QE-GES-GKIITFEAPIHSSNVM-LYSTKE-------KV--A --SRICYTL---TD--------EGKVR---MLKKTG---EILD-MGQKINPVGFRLG--IT-QEHKSRWFA------DAK H--YPDLLQEDYKIRQYI--QKNLS-----NAGISDVRIERKA-D-QIDLEVLTARPGVVVGRGGTGIESLRVGLQKEIR INVVEVAR---VDADARLIAEYIAQQLEKRVSFRRVVRQAITRAQKA-GVEGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYCTALTIYGILGIKVWVFMPTNDTISDMLTRIRNSCLARHQTTHI-PSTKMTRSIAKVLRNEGFIGEYE ETG----E---G----IKKALVLSLKYN--PKTR-------T---PIIKKLKRVSRPGLRVYSNRKELPRVLGGIGIAII STSRGVMTDREARIQGIGGEVLCYIWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLIKERVGLVVSNKMEKTVVVAIENRSPHRKYG KIVVKTRRYKAHDEE--NQCQEGDRVRIQETRPLSKTKRWNVIEILTSR------------------------------- -MSRSL-KKGPFVAD-HLLKKIAALDA---SGKKG----VIKTWSRASTILPLMVGHTIAVHNGRQHVPVFVTE-QMVGH KLGEFAPTRTYRSHA------G--GDK----KAR------R- >Microcoleus_chthonoplastes_PCC_7420 Concatenation of 16 sequences MGTRSYRPYTPSTRQVTLSDFAE-ITRD------------EP-EKSLTKSNHRPKGRNNRGVITSRR-RGGGHKRL---- YRIIDFH-R--NK-HNIPAKVASIEYDPNRNARIALLYYQ-DGEKRYILHPAGLEVGASVISGP-D-AP-IEVGNALPLS NIPLGTSVHNVELIPGKGGQIVRAAGVSAQVVAK--EGKYVTLKLPSTEVRMVQRNCYATIGQVGNSDARNLSLGKAGRS RRL------GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGAKTR-KPKKQST-A-LVVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-EEGR---------ALPVTVVQAGPCR VTQIK----TKQ----T--DGY--SAVQLGY-------HE--AVNK----------PEKGHLA----------------- ---SE-APPLRHLREYRL--------DNTDEF-----QL---GQ-VINA--E-I-FSAGQLVDVSGNTIGRGFAGYQKRH NFKR-GPMAHGS-KNHR-LPGSTG-AGTTPG-RTFPGKKMAGRYGGKRQTIRKLQVVRVDTERN---------------- ----------LLIIKGA-VPGKPGALLNIA-------M-RNWQGEEVGQATLELKVA----KE-DS-ASHIVHRALVRQM TNARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---NR-SP----LW---- RGGGIIFGPK-P-RDYNLKMNRKERRLALRTALQGRAED-------------------MIVVEEF--ADQLP-R------ --PKTKLLI--LPQPA--Q---QVYLSARNVPSIK-L---------------IYADSLNVYDVLNADK----IVTTNTAL AKIQE--------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------SRIG-K--RPITIPNKVTVT-I--- -E-G--Q-QVTVKGPKGELQRVL--PK-Q--VTIEQEG-ET--IHV---RR-R--DESRLAR-QRHGLSRTLVANMVEGV SKGFERRLAIQGVGY--RAQVQG-RN--LILN--VGYSQPVEIVP-P-E-DVQLAVE--G-NTNVIVSG-INKEIVGNTA AKIRAVR------PPEVY---KGKGIRYVGEMIRRKAGK----------MIQQQTYLNVADNSGARKVMCIRVVGSGNRR Y--GSVGDVIIAVVKDAIPN-M-------AIKKSDVVRAVIVRTRKGLRRESGMSIRFDDNAAVIIN-PEGN-PRGTRVF GPVARELR-ERNYTKIVSLAPEVLMR-I--HTVAPQDGA-KKRRRRVG-RGISAGQ-GASCGFGMRGQKSRSG---R--G TRPGF-E-GGQMPLYRRLPKLKH--FTVINVGKLVTLPSLMET-GIVTLK---------ILG--DGE-L-N-V-S-LNV- KAVAFTTGARQKIEAAGGSCEKFRKQHR--GRM---RGQA-TRGNSLNFG----------DFGLQAI--EPSWITARQIE AGRRAMTRYI------RRGGKIWIRVFPDKPVTMRPAETRMGSGK---------GSPEYWVAVVKP-GRILYEI--AG-- VPEPLAREAMRLAANKFPIKTKF-VREGE--------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MA--KAIARYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPVLKVLRSAVAN----A- EHNA-GLDPTNLVISHASADMGPSFRRYRPRAQGRAYQIRKPTCHITVAVSPKMHVKKGDTVQVISGH------DK-GKV GEILQTLPKDS--KVV--VKGVNIKTKHVK----PQ--QE-GET-GQIATIESPIHSSNVM-LYSEKQ-------KV--A --SRICYTL---TE--------EGKVR---MLKKTG---EIID-MGQKIHPIGFRLG--IT-QEHRSCWFA------DTK R--YPEVLQEDYIIRQYV--EKNLS-----NAGISMIRIERKA-D-QIDLEVHTARPGVVVGRGGSGIESLRTGLQDLIR INVIEVAR---VDADAELIAEYIAQQLERRVSFRRVVRQAIQRAQRA-DVQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYRTASTTYGILGVKVWIFMAANDTIADMLTRIRNACLVRHQTTNV-PATKMTRAIAQVLREEGFIAEFE EAG----E---G----IKKYLVISLKYK--GKTR-------Q---PIIRALKRVSKPGLRVYKNRKELPRVLGGIGIAII STSSGIMTDREARRQGIGGEVLCYIWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNAAAVGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRLIDIYQPSSKTIDALMKLDLPAGVDIEVKL-------------DKTVVVAVENRSPHPKYG KIVVNTKRYKAHDEE--NRCQEGDRVRIQETRPLSRTKRWQVTDILNSA------------------------------- -MGRSL-KKGPFIAD-SLLSKIEALNT---KGEKQ----VIKTWSRASTILPQMVGHTIAVHNGRTHVPIFINE-QMVGH KLGEFAPTRTFRGHS------K--SDR----RAR-------- >Microcoleus_vaginatus_FGP-2 Concatenation of 16 sequences MGIRSYRPYTSSTREQTVSDFAE-ITRS------------EP-EKSLTSNKHTKQGRNNRGVITCRH-RGGGHKRL---- YRDIDFR-R--DK-HSIPATVKAIEYDPNRNARIALLFYK-DGEKRYILHPLNLNVGTVIVSGP-D-AP-IEIGNALPLK NIPLGTSIHNVELVPGKGGQIVRSAGSSAQLMAK--EGSYVTLKLPSGEQRKVRADCYATIGQVGNTDARNLSLGKAGRT -RWK-----GRR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRPGPVTP---WGKPALGAKTR-RKNKRSD-A-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-DQGR---------AIPVTVIQAGPCT VTQIK----TKQ----T--DGY--GAVQLGY-------NE--ALNK----------PELGHLA----------------- ---SG-ANPLRHLQEYRL--------EDTSSF-----EL---GQ-QLKA--D-T-FTPGQIVDVIGTSIGKGFAGFQKRH NFKR-GPMSHGS-KNHR-EPGSIG-PGTTPG-RVYPGKRMAGRMGNVQVTVRKLTIVRVDTEQN---------------- ----------LLLIKGA-VPGKAGALVNVV--MVNCVV-RNWQGEEVGETTLELRVA----KE-EN-ASHIVHRALTRQL NNARQGNACTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKMNKKERRLALRTAFQSRTED-------------------IIVVEEF--AEQFP-R------ --PKSKLLI--LPEPQ--P---NVYLSGRNIELVN-V---------------ILATSLNVYDVLAADK----IIVTSTAI AKIQEKLKVLYQGKI----VPTLMDQFKYTNIHQVPKLVKVTVNRGLG-EASQNAKALDSSINEIGIITGQKPVVTRAKK AIAGFKIRKGVPVGVMVTLRGDRMYDFLDRLINLALPRIRDFRGISP-KSFDGRGNYSLGLREQLIFPEIE-----YDRI DQIRGMDISIITT-----------------------ANTDEEGRALLKEMGMPFRSRIG-K--RPISIPNKVTIT-L--- -D-G--Q-KVAVKGPKGELSRVI--PA-E--IVMGLEG-ET--LLV---TR-R--DESRVAR-QLHGLCRTLVANMVEGV SQGFQRRLEIIGTGY--RAQVQG-RN--LILN--VGYSKPVEMPP-P-E-GITMAVE--G-NTNVIVSG-IDKELVGNTA ARIRAVR------PPEVY---KGKGIRYSGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLGGGNRR Y--GGVGDVIIAVVKDAIPN-M-------AVKKSDVVRAVIVRTRKGLRRDSGMSIRFDDNAAVIIN-VDGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--QDARPKAGS-QKRPRRLG-RGISAGQ-GASSGKGMRGQKSRAG---S--G TRPGF-E-GGQNPLYRRLPKLKS--FPLINVSKLVTLTSLIQA-KIVTLK---------ILG--DGE-L-N-V-P-LQV- RASAFTAGARTKIEAAGGSCEKFRKQQR--GRM---SGIA-TRGNTVSFG----------DFALQAV--EPAWITSRQIE AGRRAMTRYI------RRGGKIWIRIFPDKPVTQRAAETRMGSGK---------GAPEFWVAVVKP-GRVMFEI--GG-- VTEEIAREAMRLASFKLPIKTKF-IRKESVQRRHRRVRRKV---FGTSERPRLAVFRSEQHIYAQVIDD---T--AQHTL AAASTL-DPEL-KSTL----SSG-GNCSASVQVGQLIAKR--CSSAG-IVKVVFDRGGNLYH--GRVKALAEAAREAGLD F--------------------------------------------------------------MV--KAIARYIRTSPFK VRRVLDQIRGKSYQEALILLEFM---------------------------------PYRACEPIVKVLRSAVAN----A- EHNA-GLDKSKLVVSQAYADQGPVLKRFRPRAQGRAYQIRKPTCHITVVVAPRMHVKAGDTVQIITGK------EK-GKV GEILKTYPKVS--KVI--VKGVNIRTKHVK----PQ--QE-GES-GKILTFEAPIHSSNVM-HYSEKE-------KI--A --SRVCYTF---SE--------DGKLR---QLKKTG---EIIDQMGQKIHPIGFRLG--IT-QEHRSRWFA------DPK N--YPELLQEDYKIRKYV--RKTLS-----NAGISSVKIERKA-D-QIDLEVFTARPGVVVGRGGAGIETLRVGLQQQIR INVVEVQR---VDADATLIAEYIAQQLERRVSFRRVVRQAITRAQKV-GIQGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAQTIYGILGIKVWVFMAANDTIADMLTRIRNSCMARHQTTQI-PATKMTRSIAQVLKSEGFIGEFE EAE---AE---G----INRHLVLSLKYK--GKTR-------K---PIITALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGIMTDREARRQGLGGEVLCYVWMQQQKIRIRLKAFDRRILDASCEKIVDTANRTAATAIGPIPLPTKRRIYCLLRS PHVDKDSR-EHFETRTHRRIIDIHQPSAKTIDALMKLDLPAGVDIEVKLIKERVGVVVSDKMDKTVVVAIENRSSHTKYG KIVVRTKRYKAHDEE--NQCKSGDRVRITETRPLSKTKRWTVAEIFGTK------------------------------- -MSRSL-KKGPFVAD-ALMTKIEKLNA---AGQKQ----VIKTWSRSSTILPQMVGHTIAVHNGRQHVPVYLTD-QMVGH KLGEFSPTRTFRGHA------K-SGDK----KAK------R- >Microcystis_aeruginosa_PCC_7806 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGSTQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VTINKDG-ET--ILV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNTA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGISAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLRKLVTLESLLKA-NILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALERG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQIVTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIRNYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_7941 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VTIDKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNIA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLKKLVTLESLLKA-NILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----AST-ATQEASAAVGKLVAQR--ALDKG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQILTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9432 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------DDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VTIDKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNIA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLKKLVTLESLLKA-NILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALDKG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQILTYEAPIHSSKVM-IYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9443 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHHKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VTINKDG-ET--ILV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNIA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGISAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLKKLVTLESLLEA-KILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKL---SGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALERG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQIVTYEAPIHSSKVM-IYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELLQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKNEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9701 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQSDN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKTDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAIDKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNIA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLRKLVTLESLLKA-KILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPIAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALDKG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQIVTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIRQYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDEE--NQAKQGDRVRIRETRPLSKTKRWQVAEILTDN------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9717 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQSDN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAINKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-STQVIVSG-IDKEAVGNIA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGISAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLKKLVTLESLLKA-NILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALERG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQILTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9806 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHHKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEERLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAIDKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNTA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLRKLVTLESLLKA-KILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPIAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALERG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQIVTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9807 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITT--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGSTQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKAELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VTINKDG-ET--ILV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RALVQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNTA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGISAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLKKLVTLESLLKA-NILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKL---SGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALERG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQILTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELLQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKNEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9808 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHRKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--A-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAIDKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-NTQVIVSG-IDKEAVGNIA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLKKLVTLESLLKA-NILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALDKG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQILTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIREYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKTIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDQRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_aeruginosa_PCC_9809 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHHKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPAKVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--D-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEEKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAINKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-STQVIVSG-IDKEAVGNTA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGISAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLRKLVTLESLLKA-KILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALDKG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- EHNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQILTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELLQEDRRIRQYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDN------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Microcystis_sp._T1-4 Concatenation of 16 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHHKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPATVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--ALNK----------PLLGHLA----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--D-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHR-LPGSTG-AGTTPG-RVFPGKRMAGQYGATQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT--MVNYTV-KNWQGEEAGTGTLELKTA----KP-ET-AKHLIHRVVISHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVLLADR----VIATAAAL AKIEERLKTTYQETI----VPKLKEQFGYTNVHQVPKVIKITVNRGLG-EASQNAKALESSKEELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--RPIPIPNQVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAINKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQLQD-GK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-STQVIVSG-IDKEAVGNTA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLGTGNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSG---T--G TRPGF-E-GGQMPLYRRVPKLKH--FPLVNLRKLVTLESLLKA-KILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTWEKFRKQQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPIAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EASL-RGEL----EST-ATQEASAAVGKLVAQR--ALERG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F--------------------------------------------------------------MT--KAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- ENNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQIVTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTF---TE--------DGKVR---ILKKTG---EIID-MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELVQEDRRIRDYV--EKNLS-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >Moorea_producta_3L Concatenation of 16 sequences MGIRSYRPYTPGTRQGTVSDFAE-ITRT------------EP-EKSLTKSKHRKKGRNNRGVITCRH-RGGGHKRL---- YRVIDFR-R--DK-HNIPAKVAAIEYDPNRNARIALLYYQ-DGEKRYILHPVGLEVGSSIISGP-D-SP-IEIGNALPLK DIPLGTNVHNVELIPGRGAQIVRAAGATAQVQAK--EGDYVTLKLPSSEVRMLRKECYATIGQVGNVEARNLSLGKAGRN -RHR-----GRR-P-QVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-KAKKQSS-S-LIVRRR --------------------------------VSV---G-ILGTKLGMTQVFD-EEGR---------AIPVTVVKAGPCT VTQIK----TNQ----T--DGY--NAIQIGY-------DQ--AINK----------PEIGHLA----------------- ---SS-APPLRHLREYRV--------DDTSNF-----EL---GQ-PVNT--D-M-FSIGQIVDVSGKSIGRGFAGYQKRH NFRR-GPMAHGS-KNHR-LPGSTG-AGTTPG-RTYPGKKMAGRYGGTKVTIRKLEVVKIDQERN---------------- ----------LLAIKGA-VPGKPGTLLSIA--MVDCSV-RNWQGEEVGQATLQMRVA----KE-EN-AAHIVHRSLVRQM ANARQGNACTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---NR-SP----LW---- RGGGVIFGPK-P-RDYSQKMNRKERRLALRTAFMSRAED-------------------LIVVEEF--TEQLP-R------ --PKTKLLI--LAQPE--E---KVYLSVRNLATVK-L---------------IYATNLNTYDILAADK----IVTTNTAL AKIQEGLKILYQETI----VPKLKEQFGYKNIHQVPKLVKVSLNRGLG-EASQNAKALESSVNEIAIITGQKPVVTRAKQ AIAGFKIRAGMPVGVTVTLRSERMYSFLERLINLALPRIRDFRGLSP-RSFDGRGNYTLGVREQLIFPEVD-----YDSI DQIRGMDITIVTT-----------------------ANTDEEGRALLKEMGMPFRSRIG-K--RPIPIPSKVTVT-I--- -D-G--Q-QVKVKGSKGELDWVL--PD-T--IKAEQVG-ET--VQV---SR-R--EETRTAR-ESHGLSRTLVANMIEGV SKGFEKRLDIQGVGY--RAQVQG-RN--LILN--VGYSKPVEIVP-P-E-GIQVKVE--N-NTNVIVSG-INKEVVGNTA AKIRAVR------PPEVY---KGKGIRYAGEIVRRKAGK----------MIQQESYLNVADNSGARKIMCIRVIGAGNRR Y--GGVGDVIIGVVKDAIPN-M-------GVKKSDVVRAVIVRTRKGLRRESGMSIRFDDNAAVIIN-PDGN-PRGTRVF GPVARELR-EKNFTKIISLAPEVLMR-I--NDAVPKKGS-KKRRRRVG-RGIAAGQ-GASCGFGMRGQKSRSG---R--G TRPGF-E-GGQMPLYRRIPKLKH--FTVINVGKLVTLESLLET-GVVTLK---------LLG--DGE-L-N-V-P-LNI- KAAAFTSGARQKIEAAGGSWE-----------M---KGMA-TRGSTINFG----------DYALQAT--EPAWITSRQIE AGRRAMTRYV------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEFWVAVVKP-GRIIYEI--AG-- VSEEVAREAMRLAANKFPIKLKF-IRKESIRHRHRRVRRKV---SGTAERPRLAVFRSNEHIYVQVIDD---N--QQHTI VAASTL-EPAL-RSEL----KSG-ATCEASAKVGQLVAQR--ALEKG-LKKVVFDRGGYLYH--GRVKALAEAAREAGLD F--------------------------------------------------------------MA--KAIARYIRMSPSK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACQPVLKVLRSAVAN----A- EHNA-GIDPASLYITKAFADMGPSLKRYRPRAQGRAYQIRKPTCHITVAVSPKMHVKKGDTVQVIAGR------DK-GKI GEILRTLPKIS--KVV--VKGVNVKTKHVK----PQ--QE-GEK-GQIATFEAPIHSSNVM-LYSNKE-------KLLAA --SAIPLP----TM--------VGLVR---LLTNYS---VTNG-MGQKIHPIGFRLG--IT-QEHRSRWFA------DSK R--YPLLLQEDYQIRQYV--DKNLN-----NAGISDIRIERKA-D-QIDLEIHTARPGVVVGRGGSGIESLRVGLQKSIR INVVEVSR---VDADATLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-DVQGIKVQVGGRLNGAEIARTEWTREGRVPL- -HTLRANIDYSYKTAQTIYGILGIKVWVFMPANDTIADMLTRIRNACLVRHQTTNV-QSTKMTRAIAQVLKEEGFITDFE EAG----E---G----VKKYLVVSLKYK--GNNR-------K---PIIRALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSNGIMTDREARRRGIGGEVLCYVWMQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHQRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLAKERVGLVVSDKMNKTVVVAIENRSPHPKYG KIVVRTKRYKAHDEE--NKCKEGDRVRIRETRPLSRTKRWMVAEIVSSS------------------------------- -MGRSL-KKGPFIAD-SLLTKIETLNA---KGEKQ----VIKTWSRASTIVPQMVGHTIAVHNGRTHVPVFINE-QMVGH KLGEFAPTRTFRGHV------K---DG----KAR------R- >Nodularia_spumigena_CCY9414 Concatenation of 16 sequences MGTRSYRPYTPSTRQVTVSDFAE-ITKS------------KP-EKSLTEYVHRPKGRNNQGRITSRR-RGGGHKQM---- YRIIDFK-R--DK-RNIPAQVIAIEYDPNRNARIALVLYQ-DGEKRYILHPNKLPVGATIIAGP-D-SP-FEDGNALPLL NIPLGTSVHNVELTPGKGGQIVRAAGANAQVVAK--EGQYVTLKLPSGEVRMIRRECYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRPGPVTP---WGKPTLGAKTR-KPKKASS-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-EAGV---------SIPVTVVQAGPCT VTQVK----TKQ----T--DGY--SAIQLGY-------GE--ALNR----------PLLGHLA----------------- ---SS-APALRHLNEYHT--------DSPSDY-----AL---GQ-ELKA--D-I-FSEGQIVDVVGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHR-APGSIG-AGTTPG-RVYPGKRMAGRLGGTRVTIRKLTVVRVDLERN---------------- ----------LLLIKGA-IPGKPGSLVNIL--MVESVV-KNWQGEQVGETTFELRVA----KE-ST-ASHIVHRALVRQM TNSRQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYNQKLNRKERRLALRTAFVSRADD-------------------LIVVQDF--SNELS-R------ --PKTKLLI--MPIISS-E--DNVYLSARNIQNLK-L---------------IAADQLNVYDLLHADK----IVITASAL AKIQERLKNLYQETI----VPKLTNQFQYTNVHQVPKVIKITINRGLG-EAAQNAKSLEASLNEIAVITGQKPVVTRAKK AIAGFKIREGMPVGIMVTLRGERMYAFLDRLISLSLPRIRDFRGISP-KSFDGRGNYTLGVREQLIFPEVE-----YDSI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--QPITIPAKVEVT-I--- -D-G--P-KVVVKGPKGQLSRTL--SA-N--VIVSQEG-GI--LNV---TR-R--DETRVSR-QMHGLSRTLVANMVEGV SQGFKRRLEIQGVGY--RAQLQG-RN--LVLN--IGYSHQVNIVP-P-D-GVEFLVE--T-NTNIVVSG-YDKEIVGNTA AKIRAVR------PPEPY---KGKGIRYAGEVVRRKAGK----------MIQTQTYLNVADNSGAKKIMCIRVLGGGNRR Y--GFIGDRIIAVVKDAIPN-M-------AVKKSDVIEAVIVRTRHSIRRDSGMTIRFDDNAAVIIN-KDGN-PRGTRVF GPVARELR-EKSFTKIVSLAPEVLMR-L--NDVKPQKGS-KKRRRRVA-RGISAGQ-GASAGLGMRGQKSRSG---S--G TRPGF-E-GGQQPLYRRVPKLKG--FPVINVEKLVTLASLREA-GILTLK---------VLG--NGE-L-N-V-S-LKV- QAAAFTGQARSKIEAAGGSCEKFRKQQR--GRM---QGLA-TRGCNIDFG----------DFALQAQ--EPSWITARQIE ASRRAMTRYI------RRGGQIWIRIFPDKPITMRAAETRMGSGK---------GNPEYWVAVVKP-GRIMFEI--AG-- VTEEIAREAMRLAANKLPIKTKF-IRRESKQRRHRRVRGKV---QGTRERPRLAVFRSNEHIYAQVIDD---T--QHHTL VAASTV-EPEL-KSNL----ATG-ATCDASAQVGKLIAVR--LLEKG-ITKVVFDRGGNLYH--GRVKALADAAREAGLD F--------------------------------------------------------------MA--KAIARYIRISPYK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPVLKLLRSAAAN----A- EHNA-GLDRTNLVITQAYANQGPVLKRFQPRAQGRAYQIRKPTCHITVAVADKMHVKTGDTVQVIAGK------DK-GKV GEIVQALPQLS--KVI--IKGVNMKTKHVK----PQ--QE-GES-GKIVTQEFPIHSSNVM-LYSSKQ-------NV--T --SRVCYTF---TA--------EGKVR---MLKKTG---EILNNMGQKIHPVGFRLG--IT-REHQSRWFA------VPE R--YPELLQEDYKLRQYI--EKKLGKLAQNNAGISEVRIERKA-D-QIDLEVRTARPGVVVGRGGQGIESLRLGLQEVIR INVVEVQK---VDADASLIGEYIAQQLERRVSFRRVVRQAIQRAQRA-GVQGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYCTAKTIYGILGIKVWVFMAANDTVADMLTRIRNANLARHQTTQV-PATKMTRSIAKVLQEEGFVAEVA EAG----E---G----IKRNLVISLKYK--GKNR-------Q---PLITALKRVSKPGLRVYSTRKELPRVLGGIGIAII STSSGIMTDREARRQSLGGEVLCYVWMQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDAR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKLIKERVGLVVSDKMQKTVVVAIENRSPHPKYG KIMVKTRRYKVHDEE--NQCKVGDRVRIQETRPLSKTKRWQVKDILNTK------------------------------- -MGRSL-KKGPFVAD-HLLTKIEKLNA---KNEKQ----VIKTWSRASTILPLMIGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTYRGHG------K--SDK----KAG------R- >Nostoc_azollae_0708 Concatenation of 16 sequences MGTRSYRPYTPSTRQVTISDFAE-ITKT------------DP-EKSLTESVHRPKGRNNQGRITSRR-RGGGHKQL---- YRIIDFK-R--DK-RDIAATVTAIEYDPNRNARIALVQYE-DGEKRYMLHPNGLKVGTTIIAGV-D-AP-FEDGNALPLS KIPLGTNVHNVEMTPGKGGQIVRAAGATAQVVAK--EGNYVTLKLPSGEVRMIRRECYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-KRKKAST-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQIFD-EAGV---------AIPVTVIQAGPCT VTQVK----TKQ----T--DGY--CAIQVGY-------GV--VLNR----------PLLGHLA----------------- ---SS-APALRHLNEYRT--------DASGDY-----AL---GQ-ELKA--D-I-FSAGQIVDVIGTSIGRGFAGNQKRN HFGR-GPMSHGS-KNHR-APGSIG-AGTTPG-RVYPGKRMAGRLGGTRVTIRKLTIVRLDADRN---------------- ----------LILIKGA-IPGKPGALVNIV--MVESVV-KNWQGEQVGETSFDLRVA----KQ-ET-AAHIVHRALVRQM TNSRQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFNLKLNRKERRLALRTAFVSRAED-------------------LIVVEEF--SNELQ-R------ --PKTKLLI--LSEIA--E---NVLLSARNIENLK-L---------------IAADQLNVYDLLHADK----IVVTPAAL EKIQERLKNLYQETI----VPKLTQQFQYTNVHQVPKVIKITVNRGLG-EAAQNAKALEASLNEIALVTGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRGERMYAFLDRLVSLALPRIRDFRGVSP-KSFDGRGNYTLGVREQLIFPEVE-----YDSI DQIRGLDISIITT-----------------------AKNDEEGRALLKEMGMPFRSRIG-K--CPITVPAKVQVA-I--- -D-G--S-KVVVKGPKGELSRNL--PP-H--VTVSQEG-ET--LLV---TR-R--DDTRTSR-QMHGLSRTLVANMVEGV SQGFQRRLEIQGVGY--RAQVQG-RN--LVLN--MGYSHQVQIEP-P-D-GIQFAVE--G-TINVIVSG-YDKEIVGNTA AKIRAVR------PPEPY---KGKGIRYVGEVVRRKAGK----------MIQPQSYLNVADNSGARKLMCIRVLGGGNRR Y--GGVGDKIIAVVKDAQPN-M-------AVKKSDVVEAVIVRTRKSINRDSGMSIRFDDNAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--NDVKPQKGS-KKRRKRVG-RGISAGQ-GASAGLGMRGQKSRSG---S--G TRPGF-E-GGQQPLYRRVPKLKG--FPLINVEKLVTLASLRQA-GILTLK---------VLG--NGE-L-N-V-P-LKV- QAAAFTGQARIKIEAVGGSCEKFRKQQR--GRM---EGLA-NRGSTLNFG----------DFALQAQ--EPAWITSRQIE ASRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEI--AG-- VSEEIAREAMRLAAYKLPIKTKF-IRRESKNRRHRRVRGKV---SGSPERPRLAVFRSNEHIYAQVIDD---T--QHQTL VAASTV-EPEL-KSNL----ASG-ANCDASAQVGKLIAVR--SLEKG-ITKVVFDRGGNLYH--GRIKALAEAAREAGLD F--------------------------------------------------------------MA-Q-AIARYIRISPYK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPVLKVLRSAAAN----A- EHNE-GLDRSELVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITVAVGAKMHVKTGDTVQVIAGK------DK-GKV GEVIKALPQLS--KVL--VKGVNIKTKHVK----PQ--QE-GES-GKIVTQEFPIHSSNVM-LYSSKQ-------NI--A --SRVCYTF---TA--------EGKVR---MLQKTG---EILDKMGQKIHPVGFRLG--IT-QEHQSRWFA------VPD R--YPELLQEDHKLRKYI--DQKLGRYAQNNAGISEVRIERKA-D-QIDLEVRTARPGVVVGRGGQGIESLRTGLQELIR INVVEVQR---VDADAYLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-GVQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAQTIYGILGIKVWVFMAANDTIADMLTRIRNANLARHQTTQV-PATKMTRNIAKVLQDEGFIAEFS ESG----E---G----IKQNLVISLKYK--GKNR-------Q---PLITALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGIMTDREARRQNLGGEVLCYVWMQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKLVKERVGLVVSDKMQKTVVVAVENRSPHPKYG KIVVQTRRYKAHDED--NHCKVGDRVRIQETRPLSKTKRWQVTEILNAK------------------------------- -MGRSL-KKGPFIAD-HLLSKIEKLNA---KNEKQ----VIKTWSRASTILPMMVGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTYRGHG------K--SDK----KSG------R- >Oscillatoria_sp._PCC_6506 Concatenation of 16 sequences MGIRSYRPYTPSTRQHTVSDFAE-ITRS------------EP-EKSLTANKHTKQGRNNRGVITCRH-RGGGHKRL---- YRTIDFR-R--DK-LNVPGTVQAIEYDPNRNARIALVFYK-DGEKRYILHPVGLKIGTVITSGP-E-SP-IEIGNALPLI NIPLGTSVHNVELVPGKGGQIVRCAGATAQLMAK--EGDYVTLKLPSGEQRKIRAKCYATIGQVGNVEARNISIGKAGRT -RWK-----GRR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-RKNKRSD-S-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-EQGR---------AIPVTVIQAGPCT VTQIK----TKQ----T--DGY--AAIQVGY-------GD--ALNK----------PELGHLA----------------- ---SG-ATPVRHLQEYRL--------EDIGEF-----QL---GQ-QVKA--D-L-FTPGQIVDVIGTSIGKGFAGFQKRH NFKR-GPMAHGS-KNHR-QPGSIG-PGTTPG-RVYPGKRMAGRLGNVQITVRKLTVLRVDTERN---------------- ----------LLLIKGA-VPGKAGALVNVV--MVNCVV-RNWQGEEVGETTLELRVA----KE-EN-ASHIVHRALRRQM VNARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVSFGPK-P-RDFDIKMNKKERRLALRTALQSRAAED------------------FIVVEDF--SEQIA-R------ --PKTKLLI--LPEKQ--E---NIYLSGRNVPTLK-I---------------ILAGSLNIYDILAADK----IVTTATAI AKMQEQLKTTYQEKI----VPKLMDQFKYTNIHQVPKVVKVTINRGLG-EASQNAKALESSITEIGIIAGQKPVVTRAKK AIAGFKIRKGVPVGVMVTLRSDRMYAFLERLINLTLPRIRDFRGVSA-KSFDGRGNYSLGLREQLIFPEIE-----YDSI DQIRGMDISIITT-----------------------ANTDEEGRALLKEMGMPFRSRIG-K--RPISIPSKVTVT-I--- -D-G--Q-HVAVKGPKGELSRLL--PA-E--VVLELEG-ET--LLV---TR-R--DESRTAR-QLHGLCRTLVSNMVEGV SNGFQRRLEIQGVGY--RAQVQG-RN--LILN--VGYSKPVEMPP-P-E-GIQVAVE--G-NVNVIVSG-IDKELVGNTA ARIRAVR------PPEVY---KGKGIRYTGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLGGGNRR Y--AGVGDVIIAVVKDAIPN-M-------AVKKSDVVRAVVVRTRKGERRDSGMSIRFDDNAAVIIN-ADGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--QDALPKAGS-QKRPRRLG-RGISAGQ-GASSGKGMRGQKSRSG---S--G TRPGF-E-GGQNPLYRRLPKLKS--FPLINVSKLVTLASLIDA-KIVTLK---------ILG--DGE-L-N-V-A-LQV- KAAGFTAGARAKIEAAGGSCEN---------------GVA-TRGNNVSFG----------EFALQAL--EPAWITSRQIE ASRRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GAPEFWVAVIKP-GRVLFEI--GG-- VPEVTAREAMRLASFKLPIKTKF-IRKESIERRHRRVRRKV---SGTPERPRLAVFRSHQHIYAQVIDD---T--KQHTL VSASTL-DPEL-KTDL----KSG-GNCNASVQVGQLIAKR--CSSAG-ISKVVFDRGGNLYH--GRVKALAEAAREAGLD F--------------------------------------------------------------MA--KAIARYIRMSPHK VRRVLDQIRGKSYREALVLLEFM---------------------------------PYRACEPILKVLRSAAAN----A- EHNA-GMDRAQLIVSQAFADQGPVLKRFRPRAQGRAYQIRKPTCHITVAVATKMHVKKGDTVQVITGK------DK-GKV GEILKTYPQAS--KVV--VQGINVKTKHVK----PQ--QE-GES-GKITTFEGPIHSSNVM-LYSTKE-------KV--A --SRVCFTF---TE--------DGKVR---KLKKTG---EIID-MGQKIHPVGFRLG--IT-QEHRSRWFA------DAK N--YPELLQEDSKIRQYV--QKNLS-----NAGISSVKIDRKA-D-QIDLEVQTARPGVVVGRGGTGIEQLRVGLQQQIR INVVEVQR---VDADATLIAEYIAQQLERRVSFRRVVRQAITRAQKA-GIEGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAKTIYGILGVKVWVFMAANDTIADMLTRIRNSCMARHQTTEI-PSTKMTRSIAEVLKSEGFIAEIE EAG----E---G----IKRHLVLSLKYK--GKTR-------R---PIITALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGIMTDREARRQGLGGEVLCYVWMQQQKIRIRLKAFDRRILDASCEKIVDTANRTAATAIGPIPLPTKRRIFCLLRS PHVDKDSR-EHFETRTHRRIIDIHQPSAKTIDALMKLDLPAGVDIEVKLVKERVGLVVSDKMNKTVVVAVENRASHTKYG KTVVNTKKYKAHDEE--NQCKPGDRVRITETRPLSKTKHWIVAEILTTK------------------------------- ------------MAD-HLLTKIEKLNS---LGQRQ----VIKTWSRASTILPLMVGHTIAVHNGRQHVPVYLTE-QMVGH KLGEFVPTRTFRGHA------K--GDK----KAK------R- >Prochlorococcus_marinus_str._MIT_9202 Concatenation of 16 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITSA------------KP-ERSLIVSKHRVKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-RNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGVKVGQNVISGE-S-VP-IEDGNAMPLS VMPLGSSVHCVELYAGRGAQMVRSAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKPALGLKTR-KKNKPSN-K-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-DKGN---------AVPVTLIEAGPCR VTQLK----TNA----L--DGY--TAIQIGY-------GV--HISK----------PEKGHLL----------------- ---SG-EELLKHLKEYRV--------EETSSY-----EI---GN-QITV--K-N-FEVGQKVDISGKSMGRGFSGYQKRH GFSR-GPMSHGS-KNHR-APGSTG-AGTTPG-RIYPGKRMAGRYGGKQITTKGLLVLKIDDQKN---------------- ----------LLVVKGS-VPGKPGSIVNIK--MTTLET-LKWDGKKSGKVTLDLTVA----KE-TS-SADLIHRAVLRQL ANKRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RSYNLDMNRKERRLALRTALMSRVSD-------------------MKAVEDF--GSTLK-Q------ --PKTSLVI--LDSPS--D---VIKKSINNIEKVK-L---------------IAADQLNVFDILNANK----LVIGQSAI DKIQETLKNRYKESI----RPKLLKELGLKNIHQVPKVVKVNVNRGLG-EAASNSKALEASLNEMATITGQKALVTRAKK AIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTVGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------ARSDQEGKALLQELGMPFSSRIG-K--TPVLIPDKVTVD-F--- -D-G--L-IVTVKGPKGELKRQM--PE-G--VCFDKKD-NA--VVV---SP-T--TSKIFSR-QRHGLCRALIANMVEGV SQGFSKKLEIVGVGS--RAQVKG-KN--LVVS--AGYSHPIEMIP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYHDEVILRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLGS-NRR Y--AHVGDVIVATVKDALPN-M-------GVKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVIMTSL--NTLKSNSGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FEIINLEKLVNIDSLVKK-GLIFLK---------ILG--NGK-I-N-V-K-LKV- QAHAFTKVAKQKIEDAGGSCER---------------GVA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYI------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGED ITEKVAKEAMRLAQYKLPVKTKF-IRKLQTQKRHRRLRRFL---IGDATRPRLSVFRSNNHIYAQVIDD---S--AQTTI CSASTV-DKEL-REKSE---KLP-SDCNSSSIVGKLLAKR--AIKKG-VKQVIFDRGGNIYH--GRVKALADAAREAGLE F--------------------------------------------------------------MT---AHGNYIRGSASK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNL-GMDPSTLIISSAWANSGPVMKRYRPRAQGRAFSIKKQTCHISISVES---------------------------- -------------------------------------------------------------------------------- --------------------------------------------MGHKIHPSGLRLG--IT-QEHRSKWFA------TSK T--YPILLQEDFKIRTFI--EKKYG-----AAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMALQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTTTTI-PGSKMSLSIAKVLQKEGFISEIN EEG----E---G----YKSQIILGLKYS--GKNK-------F---PTIRSMQRVSKPGLRIYKNTRALPKVLGGLGVAII STSKGVMSDRDARKQGIGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCDKIIQTADTTSASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSRTTRYKAHDPE--NTCVTGDRVKIRETRPLSAHKRWAIEEILNKT------------------------------- -------------------------------------------------------------------------------- ------------------------------------------ >Raphidiopsis_brookii_D9_D9_7 Concatenation of 16 sequences MGTRSYRPYTPSTRQVTISDFAE-ITKT------------EP-EKSLTESVHRPKGRNNQGRITSRR-RGGGHKQL---- YRIIDFK-R--DK-RDITATVIAVEYDPNRNARIALLEYE-DGEKRYILHPNGLKVGAKVTAGP-Q-AP-FEDGNALPLS NIPLGTNVHNVEMTPGKGGQIVRAAGATAQLMAK--EGNYVTLKLPSGEVRMVRRECYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-KRKKASS-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQIFD-EAGV---------SIPVTVIKAGPCT VTQVK----TQP----T--DGY--CAIQVGY-------GE--ALNQ----------PKLGHLA----------------- ---SS-AGPVRYLNEYRT--------DAAGDY-----AL---GQ-EIKA--D-I-FSVGQIVDVIGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHR-APGSIG-AGTTPG-RVYPGKRMAGRLGGSRVTVRKLTVVKVDAERN---------------- ----------LILIKGA-IPGKPGGLVNVV--MVESIV-KNWQGEEVGQTSFELRIA----KE-ET-ASHIVHRALVRQM TNSRQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFNIKLNRKERRLALRTAFVSRRED-------------------LIVVEEF--TDQLQ-R------ --PKSKLLI--LSEIGQSTE--TISLSARNVENIK-V---------------IAADQLNVFDLLHADK----IVVTSSAL NKIQERLKTLYGQTI----VPKLTQQFQYTNVHQVPKVLKVTVNRGLG-EAAQNAKALEASLSEIALITGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRGERMYAFLDRLISLALPRIRDFRGVSA-KSFDGRGNYTLGVREQLIFPEIE-----YDRI DQIRGLDISIITT-----------------------AKTDEEGRALLKEMGMPFRSRIG-K--RPITIPAKVQVA-I--- -D-G--T-KVVVKGPKGELSRDL--PT-H--VTVSQSG-ET--LLV---TR-R--DDTRTSR-QMHGLSRTLVANMVEGV SQGFQRRLEIQGVGY--RAQVQG-AN--LVLN--IGYSHQVQIEP-P-A-GVQFVVE--N-NTNVIVSG-YDKEVVGNTA AKIRAVR------PPEPY---KGKGIRYAGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLGAGNRR Y--GGVGDRIIAVVKDAQPN-M-------AVKKSDVVEAVIVRTKKSINRDSGMSIRFDDNAAVIIN-KEGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVLM--L------SLKRA-LKNRKRVG-RGISAGQ-GASAGLGMRGQKSRSG---S--S TRPGF-E-GGQQPLYRRIPKLKG--FPVINVEKLVNLASLKEA-GILTLK---------VLG--NGE-L-G-V-P-LKV- QAAAFTGQARSKIEAAGGSCEE---------------GLA-HRGSTLNFG----------DFALQAQ--EPCWITSRQIE ASRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEI--AG-- VSEEIAREAMRLAAYKLPIKTKF-IRRESKQRRHRRVRGKV---NGSPERPRLSVFRSNEHIYAQIIDD---T--QHRTL VAASTV-DPQL-RSDL----ASG-ANCDASAQVGKLIAAR--SLEKG-ITKVVFDRGGNLYH--GRIQALAEAAREAGLD F--------------------------------------------------------------MA--KAIARYIRVSPYK VRRVLDQIRGLSYREALIILEFM---------------------------------PYRACEPVLKVLRSAAAN----A- EHNA-GLDRASLVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITVAVGEKMHVKTGDTVQVIAGK------DK-GKV GEVIKALPQDS--RVI--VKGVNIKTKHVK----PQ--QE-GES-GRIVSQEYPIHSSNVM-LYSTKQ-------NI--A --SRVCYTF---TE--------DGKVR---MLKKTG---EILDKMGQKIHPVGFRLG--IT-QEHQSLWFA------VPG R--YPELLQEDHKLRQYI--EQKLGRNAQNNAGLSEIHIERKA-D-QVDLELRTARPGVVVGRGGQGIEALRTGLQQLVR INVVEVQK---VDADAYLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-GVQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAQTVYGILGVKVWVF--------AMLT----WQGIKQRKCQ---QQKMTRSIAKVLQQEGFISEYT EAG----E---G----VKRNLVISLKYK--GKSR-------Q---PLITTLKRVSKPGLRVYSNKKELPRVLGGIGIAII STSSGIMTDREARRQNLGGEVLCYVWMQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIHQPSSKTIDALMKLDLPSGVDIEVKLIKERVGLVVSDKMQKTVVVAVENRSSHPKYG KTVVKTRRYKVHDAE--NSCKVGDRVRIQETRPLSKTKRWQVTEILNVK------------------------------- -MGRSLK-KGPFVAD-HLLSKLEKLNA---NNEKQ----VIKTWSRASTILPLMVGHTIAVHNGKQHVPVFVNE-QMVGH KLGEFAPTRTYRGHG------K--TDK----KSG------R- >Synechococcus_sp._BL107 Concatenation of 16 sequences MAIRKFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVSKHRKKGRNNRGVITCRH-RGGGHKRL---- YRLVDFR-R--NK-HGVTAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVQVGQTVVSGP-E-VP-IENGNAMPLS AVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-Q-YVLRKR --------------------------------MSI---G-ILGKKLGMSQLFD-EQGR---------AVPVTLIEAGPCR ITQLK----NDD----T--DGY--AAVQIGF-------GE--LINK----------PSKGHLT----------------- ---SG-EDLLRHLREYRV--------DNVDGL-----EL---GG-SITV--S-D-FEAGQKVDVSGDTMGRGFAGLQKRH GFSR-GPMTHGS-KNHR-QPGSIG-AGTTPG-RIYPGKRMSGRYGGKKTTTRGLTILRVDSDRN---------------- ----------LLVVKGS-VPGKPGALLNIK--MASCVV-RDWQGKEAGKATLDLKVA----KE-AT-AVDLMHRAVLRQQ AHMRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---VR-TP----LR---- PGGGIIFGPK-P-RSYNLAMNRKERRSALRTALMARIDD-------------------ITVVKDF--GTSLE-A------ --PKTRLIV--LTNPS--E---MVRRSVRNLEKVK-L---------------ISANHLNVFDLLHANS----LVVGEDAL TTIQESLKKRYRETI----QPKLLKDLSLSNIHEVPKVVKVTVNRGLG-EAATNAKSLEASVKELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGDRMYAFLERLINLALPRIRDFRGVSA-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARSDEEGRALLSEMGMPFQSRIG-K--NPVPVPDKVTVS-L--- -D-G--L-TVKVKGPKGELERTL--PE-G--VSVSQEA-NT--IVV---AP-T--STKRISR-ERHGLSRTLVANMIEGV HNGYSKVLEIVGVGS--RAQVKG-TT--LVVS--AGYSHPVEMPA-P-A-GITFKVE--N-NTRVIVSG-IDKELVGNEA AKVRAIR------PPEPY---KGKGIKYEGEHILRKAGK----------MIQQESFLTVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATLRRETGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERSFTKIVSLAPEVIMT-L-LDSLKANKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLY----------------------------------------------------------------- --------------------VKFRKQQR--GRM---RGVA-TRGNTIAFG----------EFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGEE ITPEIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHI---TGTSNRPRLAVFRSNNHIYAQLIDD---A--AQSTL CSASTV-DKEL-RSGL---KDNG-GSCDASVAVGALVAKR--AIAKG-IEQVVFDRGGNLYH--GRIKALADAARKAGLQ F--------------------------------------------------------------M---------------- -RRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- ENNL-GLDPASLVISSASADMGPSMKRYRPRAQGRAFQIKKQTCHISIAVAVKMRIRKGDTVQVIAGK------DK-GKT GAVLRTLPNEN--RVI--VEGVNMRTRHEK----PS--QE-GES-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---KLKKTG---EVLD-MGHKIHPTGLRLG--IT-QEHRSRWYA------SSK T--YPALLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEDLRAGIQKTVR INVVEVER---VDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVGKTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTKI-PASRMTRSIAKVLQQEGFISEIN EEG----E---G----FRAELVLSLKYS--GKHR-------L---PTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARREGVGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLVKERVGTVVSDKMEKTVVVAVETRFPHPIYQ KTVSRTTRYKAHDED--NSCRVGDRVRITETRPMSRQKRWAIAEVLSHS------------------------------- -MGRSLK-KGPFIAD-SLLRKLEKQND---NDDKS----VIKTWSRASTILPMMIGHTIAVHNGKSHIPVFITE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >Synechococcus_sp._CB0101 Concatenation of 16 sequences MGIRKYRPITPGTRTRVASDFAE-VTGR------------GR-ERGLVVAKHQRKGRNNRGVITCRH-RGGGHKRL---- YRLVDFR-R--DK-HGVVAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVAVGSTVVSGP-E-AP-IENGNALPLS AIPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-DEGR---------SIPVTVIEAGPCR ITQLK----TDS----T--DGY--TAVQLGF-------GD--LVNK----------PAKGHLA----------------- ---SG-SEPLRHLKEYRV--------DTVDGL-----EL---GG-AITV--A-A-FEAGQKVDVSGDTIGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RVYPGKRMAGRYGGKQITTRGLVILKVDAERN---------------- ----------LLVVKGS-VPGKPGALLNIL--MANCVV-RDWQGKEAGKATLELKVA----KE-TS-ANDLVHRAVVRQL AHARQGTASTLTRAE--------VA-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGVVFGPK-P-RTYNLAMNRKERRLALRTALMSRAAD-------------------ITVVKGF--AAGLD-T------ --PKTKLVV--LDAPS--E---VVRRSVRNLEKVK-L---------------IAADQLNVFDLLHANH----LVVSEEAL AKIQESLKQNYREKI----QPKLLKDLNLSNIHEVPKLVKVTVNRGLG-EAAQNAKALEASIEELATITGQKVNVTRAKK AIAGFKIRQGMPIGVAVTLRGDRMYAFLERLIHLALPRIRDFRGVSE-KSFDGRGNYTLGVKEQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARNDEEGRALLREMGMPFRSRIG-K--APIPVPGGVTVT-L--- -S-G--L-DVKVKGPKGELSRTL--PD-G--VTIAQDG-SN--LVV---SP-A--SDNRRSR-ERHGLCRTLVANMVEGV SKGYTRKLEIVGVGY--RAAVQG-KK--LVVS--AGYSHQVEMVP-P-D-GVTFAVD--G-NTTVLVTG-ADKELVGNEA AKVRAIR------PPEPY---KGKGIKYEGERILRKAGK----------MIQQETFLNVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATLRRVNGNSIRFDDNAAVILG-TDNN-PKGTRVF GPVARELR-DRNFTKIVSLAPEVI-------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------M---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGAD ITPEIAKEAMRLAQYKLPVKTKF-LRKQQTQKRHRRLRRNL---SGTAARPRLAVFRSNNHIYAQVIDD---E--AQSTL CSASTV-DKEL-RSNV----SAA-ATCDASVAVGQLVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MA---AHGRYIRGSVSK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPSSLVISSATADMGPVMKRYRPRAQGRAYAIQKKTCHISIAVAPKMRIKKGDTVQVISGK------DK-GKT GEVLRTLPYEN--RVV--VQGVNLRTRHVK----PT--QE-GET-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---RLKKTG---EILD-MGHKIHPTGLRLG--IT-QEHRSRWYA------PSK T--YPTLLQEDDRIRKFI--HKKYG-----AAGISDVVIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAYLLAEYIAQQLEKRVAFRRVMRMAIQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVATTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHQSTKV-PASRMARSIAKVLQQEGFIAEIS EEG----E---G----VEKHLVLELKYS--GKHR-------Q---PLIRTVQRVSKPGLRIYKNTRQLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLAYVYMAQQKIRIRLKAFDRRMLDLSCEKIIETADHTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLTKERVGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTKRYKAHDEE--NACKVGDRVRITETRPLSRTKRWAVAEVLNTS------------------------------- -MGRSLK-KGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGKAHVPVYVTE-QMVGH KLGEFAPTRNFRGHI------K---DK----KGG------R- >Synechococcus_sp._CB0205 Concatenation of 16 sequences MGIRKYRPITPGTRTRVASDFAE-VTGR------------GR-ERGLVVAKHQRKGRNNRGVITCRH-RGGGHKRL---- YRLVDFR-R--NK-HGVVAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVTVGSTVVSGP-D-AP-IETGNALPLS AIPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNAEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-DEGR---------AIPVTVIEAGPCR ITQLK----TDS----T--DGY--TAVQLGF-------GD--LVSK----------PAKGHLA----------------- ---SG-DELLRHLKEYRV--------DSVDGL-----EL---GG-DVTV--A-A-FEAGQKVDVSGDTIGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RVYPGKRMAGRYGGKQITTRGLTILKVDAERN---------------- ----------LLVVKGS-VPGKPGALLNIL--MANCVV-RDWQGKEAGKASLDLKVA----KE-SS-ANDLVHRAVVRQL AHARQGTASTLTRAE--------VA-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGVVFGPK-P-RTYNLAMNRKERRLALRTALMSRAAD-------------------ITVVKGF--ASGLE-T------ --PKTKLVV--LDAPS--E---VVRRSVRNLEKVK-L---------------IAADQLNVFDLLHANS----LVVSEEAL AKIQESLKQNYREKI----QPKLLKDLSLSNIHEVPKVVKVTVNRGLG-EAAANAKALEASIEELATITGQKVVVTRAKK AIAGFKIRQGMPIGVAVTLRGDRMYAFLERLINLALPRIRDFRGVSE-KSFDGRGNYTLGVKEQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARNDEEGRALLREMGMPFRSRIG-K--SPIPVPGGVTVS-L--- -N-G--L-DVKVKGPKGELSRTL--PE-G--VAIAQDG-ST--LVV---SP-S--STSRRSR-ERHGLCRTLVANMVEGV SQGFTRKLEIVGVGY--RAAVQG-KK--LVVS--AGYSHQVEMIA-P-E-GVTFAVD--G-NTTVIVSG-PDKELVGNEA AKVRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQETFLNVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATMRRVNGNSIRFDDNAAVILG-TDNN-PKGTRVF GPVARELR-DRNFTKIVSLAPEVIMTSLNLQSLAPQKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FTVINVAKLVNIDTLVKD-GLVTLK---------VLG--NGE-L-S-V-K-LTV- QAAAFTASARQKIEAAGGTCE------R---------GVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGAE ITPEIAKEAMRLAQYKLPVKTKF-LRKQQTQKRHRRLRRNL---SGTAARPRLAVFRSNNHIYAQVIDD---V--AQSTL CSASTV-DKEL-RSNV----TIG-ATCDASVAVGQLVAKR--ALAKG-IQSVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MS--------------K VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPASLVISVATADMGPVMKRYRPRAQGRAYAIQKKTCHISIAVAPKMRIKKGDTVQVISGK------DK-GKT GEVLRTLPYEN--RVV--VQGINLRTRHMK----PT--QE-GET-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---RLKKTG---EILD-MGHKIHPTGLRLG--IT-QEHRSRWYA------PSK T--YPSLLKEDDQIRKFI--HKKYG-----AAGISDVVIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRVMRMAIQRAQRA-GVLGMKLQVSGRLNGAEIARTEWSREGRVPL- -HTLRADIDYATKVATTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHQSTKV-PASRMAQSIAKVLQQEGFIAEIT EEG----E---G----VMKHLVLELKYS--GKHR-------Q---PIIRTVQRVSKPGLRVYKNTRQLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLAYVYMAQQKIRIRLKAFDRRMLDLSCEKIIETADHTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKL------------------------------G ----------------------------------------------R--------------------------------- -----LK-KGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGKAHVPVYVTE-QMVGH KLGEFAPTRNFRGHI------K---DK----KGG------R- >Synechococcus_sp._PCC_7335 Concatenation of 16 sequences MGIRSYRPLTPGTRERTVSDFST-VTAD------------KP-EKSLTYSVHRPKGRNNRGVITCRH-RGGGHKRL---- YREIDFR-R--NK-FNVPAKVATIEYDPNRNARISLLHYE-DGEKRYILHPIGLEVGATIVSGE-D-AP-FEVGNALPLH RIPLGTTVHNVELVPGRGGQVVRAAGAGAQLVAK--EGGYVTLKLPSSEVRMIRRECYATIGQVGNVEHRNLSLGKAGRK -RWA-----GRR-P-EVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGYKTR-KKKKGSD-A-MIVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-ETGN---------AIPVTVIQAGPCV VTQIK----TEK----T--DGY--SSVQIGY-------GE--ALNR----------PKLGHLK----------------- ---SG-ASPLRHLREYRV--------SDTGEF-----EL---GQ-ALAA--D-R-FEAGQTIDVSGISIGKGFAGNQKRN NFRR-GPMSHGS-KNHR-APGSTG-AGTTPG-RVYPGKKMAGRMGSEKVTIRKLSVVRVDSDRN---------------- ----------LLLVKGG-VPGKAGTLLNIT--MVDCVV-KNWQGEEAGSVSLELKVA----SE-EN-ASHIVHRALVRQI NNGRQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYTTKMNRKERRLALRTAFQSRANE-------------------MTVVKDF--AAELT-Q------ --PKTKLMV--FSERN--D---NVYLSLRNVPNVR-M---------------IDATNLNIYDILHADS----LVVTESAL EKIQESLKTLYLDKA----VPKLKEQFGYTNPHQVPKLAKVTVNRGLG-EASQNAKALESSINELAVITGQRPVVTRAKK AIAGFKIREGMPVGVKVTLRADRMYAFTNRLINLTLPRIRDFRGVSP-RSFDGRGNYTLGLREQLIFPEVD-----YDSV DQIRGMDITIVTT-----------------------ATSDEEGRALLKELGMPFRSRIG-K--QPVPIPKGVTVT-I--- -D-G--Q-MLTAKGSKGELSREF--PP-E--IAIEQTG-EE--VVV---TR-V--NESRNAR-QRHGLVRTLVANMVEGV SKGYEKKLEIQGVGY--RASLQG-QK--LVMA--LGYSHPIEFDP-P-S-GITFAVE--K-NTNVTVTG-IDKEIVGNTA AKVRAAR------PPEPY---KGKGVRYAGEQIRRKAGK----------MIQQETFLNVADNSGARKLMCIRVLG-GRKQ Y--AGVGDIIVAVVKDALPN-M-------GVKKSDVVKAVVVRTRKGIRRASGMSIRFDDNAAVLIN-QDGN-PRGTRVF GPVARELR-DKSFTKIVSLAPEVLMR-L--DDARPKAGS-KKRRNRKG-RGISAGQ-GASCGFGMRGQKSRSG---S--G TRPGF-E-GGQMPLYRRVPKLKH--FTTINVKGLVTLASLMEA-GVITLK---------VLG--DGE-I-S-T-A-LNV- KAAAFTKSAKAKIEAAGGSCE------R---------GMA-YRGNEINFG----------QFALQAT--ECCWMTSRQIE AARRAMTRYI------KRGGKIWIRVFPDKSVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRIVFEI--AG-- VSEEVAREAMRLASFKLPFKTKF-VRRESTRRRHSRVRRRV---KGTSERPRLAIFRSNQHIYAQIIDD---T--EHQTL ASASTL-DKD--AGT-----SSG-SNKDAASTVGKLIAER--AIAKD-ISQVVFDRGGKLYH--GRVAALADAAREAGLK F--------------------------------------------------------------MI--KATAKFVRMSPRK VRRVLDQIRGRSYREALIMLEFM---------------------------------PYKSCEPILKVLRSAVAN----A- EHNN-GLDPVSLYISEAYADQGPVLKRFRPRAQGRAYQIRKPTCHIAIAVAP---------------------------- -------------------------------------------------------------------------------- --------------------------------------------MGQKIHPIGLRLG--IT-QEHRSRWYA------DKN R--YPELLEEDHNIREYV--IKNLA-----NAGISDVHIERKA-D-QIDLEVRTARPGVVVGRGGAGIESLRSGLQKQIR INVVEVSK---VDADAGLICEYITQQLERRVSFRRVVRQAIQRAQRA-GVEGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRANIDYAYRTAQTTYGILGVKTWVFMASNDTISDMLTRIRNATLARHQTVDI-PSTKMTRSIATVLKEEGFIADSL DGG----E---G----IDRKITITLKYK--GKTR-------Q---PIITKLSRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGVMTDRDARRQGIGGEVLCYIYMQQQKIRIRLKAFDRRLLDTSCEKIVETANRTNATAVGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSRTIDALMKLDLPAGVDIEVKLAKERVGLVVSNKMDKTVVVAVESRVQHKKYD KIMVRTQRYKAHDEN--NTCKEGDRVKISETRPMSRHKRWVVADILSSS------------------------------- ------L-----MAD-HLLTKIEKLNA---RNEKQ----VVKTWSRSSTIIPQFIGHTVAVHNGRQHVPVFINE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >Synechococcus_sp._RS9916 Concatenation of 16 sequences MAIRTFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRVVDFR-R--NK-HGVPAKVAAIHYDPHRNAHLALLFYT-DGEKRYILAPAGVTVGQTVVSGP-E-SP-IENGNALPLS AIPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-K-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-EQGK---------AVPVTLIEAGPCR ITQLK----TSE----T--DGY--SAVQIGF-------GE--LINK----------PAKGHLA----------------- ---SG-EELLRHLSEYRV--------DDVSGF-----EL---GN-QVTV--G-D-FEAGQKVDVSGDSMGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RIYPGKRMAGRYGGKKITTRGLTIIKVDSERN---------------- ----------LLVVKGS-VPGKPGSLLNIR--MANCVV-KDWQGKDAGKASLELKVA----KE-TT-ANDLMHRAVLRQQ AHSRQGTASTLTRAE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIVFGPK-P-RTYNLAMNRKERRLALRTALMARVED-------------------LVVVKDF--GTNLE-A------ --PKTRLLV--LTNPS--E---VVRRSVRNLEKVK-L---------------IAADQLNVFDLLNANN----LVVGETAL ATIQESLKQRYRETI----QPKLLKDLSLSNVHEVPKVLKVTVNRGLG-EAAQNAKSLEASVNELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGDRMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDQI DAIRGMDITIVTT-----------------------ARSDEEGRALLREMGMPFRSRIG-K--SPIPIPDKVNVT-L--- -D-G--L-AVTVKGPKGELKRTL--PD-G--VTVSQVD-NT--IVV---AP-S--SDKRRSR-ERHGLCRTLVANMVEGV NNGFSKKLEIVGVGN--RAQVKG-KT--LVVS--AGYSHPVEVVP-P-E-GITFAVE--N-NTNVTVSG-TDKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQETFLTVADNSGAKRIQCIRVLGS-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATMRRDTGNSIRFDDNAAVIIN-ADNN-PKGTRVF GPVARELR-ERNFTKIVSLAPEVIMT-LRLDSLQANKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FPLVNVSALVNLDSLVKD-GVVTLK---------VLG--NGE-L-K-V-K-LTV- QAAAFTASARTKIEAAGGSCEKFRKQQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPITMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGDE ITPEIAREAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHL---IGSAERPRLAVFRSNNHIYAQVIDD---D--AQSTL CSASTI-DKEL-RTSL---KADG-SSCDASVAVGALVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MT-Q-AHGRFIRGSVSK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GMDPSTLVITTATADMGPSMKRYRPRAQGRAYQIKKQTCHISIAVAAKMRLRKGDTVQVISGK------DK-GKT GEVLRTLPNEN--RVI--VQGINLRTRHVK----PT--QE-GES-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVELIT---EK--------DGKKR---RLKKTG---EVID-MGHKIHPTGLRLG--IT-QEHRSRWYA------SSK N--YPSLLQEDDRIRRFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHQSTKI-PASRMSRSIAKVLQQEGFIAEIS EEG----E---G----IHSNLVLELKYS--GKHR-------Q---PTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERVGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDEG--NNCRVGDRVRITETRPMSRHKRWAIAEVLSHS------------------------------- -MGRSLK-KGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGRTHVPVFVTE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >Synechococcus_sp._RS9917 Concatenation of 16 sequences MAIRTFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVSKHRRKGRNNRGVITCRH-RGGGHKRL---- YRTVDFR-R--NK-HGVPAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVTVGQTVVSGP-E-AP-IENGNAMPLS AVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-K-FVLRKR --------------------------------MSI---G-ILGKKLGMSQLFD-EQGK---------AVPVTLIEAGPCR ITQLK----TTE----T--DGY--AAVQIGF-------GD--LVNK----------PAKGHLA----------------- ---SG-EELLRHLSEYRV--------DDVAGL-----EL---GG-AITV--G-D-FEAGQKVDVSGDSMGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RIYPGKRMAGRYGGKKITTRGLTILKIDSERN---------------- ----------LLVVKGS-VPGKPGSLLNIR--MATCVV-RDWQGKDAGKASLDLKVA----KE-ST-ATDLMHRAVLRQQ AHMRQGTASTLTRAE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIVFGPK-P-RSYNLAMNRKERRLALRTALMARFEA-------------------ITVVKDF--GASLD-V------ --PKTRLII--LSNPS--E---VVRRSVRNLDKVK-L---------------IAADQLNVFDLLNAQA----LVVGEDAL ATIQESLKQRYRETI----QPKLLKDLSLSNIHEVPKVVKVTVNRGLG-EAAQNAKALEASVSELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARTDEEGRALLREMGMPFRSRIG-K--SPIPIPDKVSVS-L--- -D-G--L-AVTVKGPKGELKRTL--PD-G--VTISQVE-NT--LVV---AP-S--SEKRKSR-ERHGLCRTLVANMVEGV STGFTKKLEIVGVGN--RAQVKG-KT--LVVS--AGYSHPIEMVP-P-E-GITFAVE--N-NTNVTVSG-SDKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQETFLTVADNSGAKRIQCIRVLGS-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATLRRDTGNSIRFDDNAAVIIN-ADNN-PRGTRVF GPVARELR-ERNFTKIVSLAPEVIMT-LRLDSLQANKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FPLVNVSALVNLDSLVKD-GIVTLK---------ILG--NGE-L-K-A-K-LTV- QAAAFTASARAKIEAAGGSCEKFRKQQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRHV------KRGGKIWIRIFPDKPITMRPAETRMGSGK---------GNPEFWVAVIKP-GRVLFEM--GGAE ITESIAREAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHL---SGSADRPRLAVFRSNNHIYAQVIDD---E--AQSTL CSASTL-DKDL-RTSL---KADG-SSCDASIAVGELVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLH F--------------------------------------------------------------MT--RAHGRFIRGSVSK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPSTLVIAQASADMGPSMKRYRPRAQGRAYAIKKQTCHISIAVAAKMRLRKGDTVQVISGK------DK-GKT GEVLRTLPYEN--RVV--VQGINLRTRHVK----PT--QE-GES-GRIVTEEASLHASNVM-LYSTSQ-------KV--A --SRVEMVT---EK--------DGKKR---RLKKTG---EVID-MGHKIHPTGLRLG--IT-QEHRSRWYA------SSR N--YPTLLQEDDRIRKFI--HKKYG-----AAGISEVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHQSTKV-PASRMSRSIAKVLQQEGFIAEIS EEG----E---G----VQTHLVLELKYS--GKHR-------Q---PTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLTKERVGTVVSDKMDKTVVVAVENRFPHPIYK KTVSRTTRYKAHDED--NSCRVGDRVRITETRPLSRHKRWAIAEVLSHS------------------------------- -MGRSLK-KGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGKTHVPVFVTE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >Synechococcus_sp._WH_5701 Concatenation of 16 sequences MAIRNYRPYTPGTRGRSSSDFSE-VTER------------RP-ERSLVVAKHRQKGRNNRGVITCRH-RGGGHKRL---- YRLVDFR-R--DK-TGVVARVAAIHYDPHRNARLALLFYT-DGEKRYILAPAGITVGQTVVSGP-E-AP-IEVGNALPLS AIPLGSSVHNVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECFATLGEVGNAEVRNTSLGKAGRT -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSF---G-ILGKKLGMSQFFD-PNGK---------SIPVTVIEAGPCR ITQLK----TPA----T--DGY--SAAQIGF-------GE--LVNK----------PAAGHLA----------------- ---SG-DELLRHLQEYRL--------ESLDGL-----EL---GA-SITV--E-A-FEAGQKVDVSGDTVGRGFSGYQKRH GFSR-GPMSHGS-KNHR-EPGSTG-AGTTPG-RVYPGKRMAGRYGGKQITTRGLTILKVDHERN---------------- ----------LLVVKGS-VPGKPGALLSIR--MVNCVV-RDWQGKEAGEASLDLKVA----KK-SS-AADLVHRAVVRQL ANARQGTASTLTRAE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGVIFGPK-P-RSYTLAMNRKERRLALRTALISRAAD-------------------ILVVKGF--AADLE-V------ --PKTKLLV--LDAPG--D---VVRRSVRNLEKVK-L---------------IAADQLNVFDLLHANV----LVLSEEAL AKIQESLKQRYRETI----QPKLLKDLTLSNIHEVPKVVKVTVNRGLG-EAAQNAKALEASISELATITGQKVVVTRAKK AIAGFKIRQGMPIGVAVTLRGDRMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----YDKI DAIRGMDITIVTS-----------------------ARNDEEGRALLREMGMPFRSRIG-K--APIPIPDKVNVT-L--- -A-G--L-AVTVKGPKGELSRTL--PD-G--VVVSQQE-NT--LLV---TP-S--NGSRRSR-ERHGLCRTLVANMVEGV SQGFTRKLEIIGVGY--RAQVQG-RK--LVVS--AGYSHPVEVNP-P-E-GVSFTVE--G-TTQVMVSG-ADKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQETFLNVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTRATLRRDTGNAIRFDDNAAVILG-TDNN-PKGTRVF GPVARELR-ERNFTKIVSLAPEVIMT-LSLSTLTPQTGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRIPKLKH--FPLLNVGKLVTLDSLVEA-GLVTLK---------ILG--NGE-L-S-I-K-LSV- EAAAFTASARAKIEAAGGTCE---C------------GVA-SRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGAE ITEAIAKEAMRLAQYKLPIKTKF-LRKQQTQKRHRRLRRHL---NGTSDRPRLAVFRSNNHIYAQVIDD---A--AQTTL CAASTL-DKDL-RSSL----ESS-ACCDASVAVGQLLATR--AIAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MA--RAHGRYIRGSVSK VRRVLDQIRGRTYREALILLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNM-GLDPASLVISTASADMGPSLKRFRPRAQGRAYAIKKQTCHISIAVAPKMRIRKGDTVQVIAGK------DK-GKT GAVLRTLPNEN--RVI--VEGVNMRTRHEK----PS--QE-GES-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---KLKKTG---EVLD-MGHKIHPTGLRLG--IT-QDHRSRWYA------PSK T--YPTLLQEDDRIRCFI--HKKYA-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRAGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRVMRMTVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVATTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKKHQTTKV-PASRLSHSIAKVLQHEGFIAQIS EEG----E---G----VERFLVLELKYS--GKHR-------Q---PTIRSVQRVSKPGLRIYKNTRQLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYIYMAQQKIRIRLKAFDRRMLDLSCEKIIETADHTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPTAKTIDALMKLDLPSGVDIEVKLLKERVGVVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDED--NRCRVGDRVRITETRPLSRTKRWAVAEVFTTS------------------------------- -MGRSLK-KGPFVAD-HLLRKVEAQNS---AGDKT----VIKTWSRASTILPMMIGHTIAVHNGKSHVPVYVTE-QMVGH KLGEFAPTRTFRGHI------K---DK----KGA------R- >Synechococcus_sp._WH_7805 Concatenation of 16 sequences MAIRTFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVPKHRRKGRNNRGVITCRH-RGGGHKRQ---- YRVVDFR-R--NK-HGVPAKVAAIHYDPHRNARLALLFYT-DGEKRYILAPAGITVGQTVISGP-D-AP-IEDGNAMPLS SVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-K-FVLRKR --------------------------------MSI---G-ILGKKLGMSQLFD-EQGK---------AVPVTLIEAGPCR ITQLK----TTE----T--DGY--SAVQIGF-------GE--LVNK----------PAKGHLA----------------- ---SG-EGVLRHLSEYRV--------DDVDGL-----EL---GG-AVTV--G-D-FEAGQKVDVSGDTMGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RIYPGKRMAGRYGGKKTTTRGLTILRVDSDRN---------------- ----------LLVVKGS-VPGKPGALLNIR--MANCVV-RDWQGKEAGKASLDLKVA----KE-TT-ALDLMHRAVLRQQ AHSRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIVFGPK-P-RTYNLAMNRKERRLALRTALMARIDD-------------------VTVVKDF--GASLE-A------ --PKTRLIV--VGNPS--E---VLRRSVRNLEKVK-L---------------IAANQLNVFDLLHANA----LVLGEEAL ATIQESLKQRYRETI----QPKLLKDLSLSNIHEVPKVVKVTVNRGLG-EAAQNAKSLEASVNELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARTDEEGRALLREMGMPFRSRIG-K--SPIPIPDKVSVS-L--- -D-G--L-AVTVKGPKGELKRTL--PD-G--VSVNQVE-NT--IVV---AP-T--SEKRLSR-ERHGLCRTLVANMIEGV SNGYSKKLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEVQA-P-E-GITFAVE--N-NTNVTVSG-TDKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQESFLTVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAMPN-M-------GVKKSDVVKAVVVRTKATLRRDTGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERNFTKIVSLAPEVIMT-LRLESLKSNKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FPLVNVSALVNLDSLVKG-GIVTLK---------ILG--NGE-L-K-T-K-LTV- QAAAFTASARTKIEAAGGTCEKFRKQQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGDE ITPEIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHL---SGTADRPRLAVFRSNSHIYAQVIDD---A--AQSTL CSASTL-DKDL-RTSI---KDTG-STCDASVAVGELVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MT-Q-AHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPSTLVISQASADMGPSMKRYRPRAQGRAYAIKKQTCHISIAVASKMRLRKGDTVKVIAGK------DK-GKT GEVLRTLPNEN--RVI--VEGVNMRTRHVK----PT--QE-GES-GRIVTEEASLHASNVM-LYSTTK-------KV--A --SRVELIT---EK--------DGKKR---RLKKTG---EVID-MGHKIHPTGLRLG--IT-QEHRSRWYA------SSK S--YPTLLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEDLRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHQNTKV-PASRMSRSIAKVLQQEGFIAEIS EEG----E---G----VHTNLVLELKYS--GKHR-------L---PTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERVGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDEN--NSVRVGDRVRITETRPLSRHKRWAVAEVLSHS------------------------------- -MGRSLK-KGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGKTHVPVFVTE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >Synechococcus_sp._WH_8109 Concatenation of 16 sequences MAIRNFRPYTPGTRTRVVTDFSE-ITSR------------KP-ERTLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRVVDFR-R--NK-HGVPAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVQVGQTVVSGP-D-AP-IENGNAMPLS SVPLGSAVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEMRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-Q-YVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-EQGR---------AVPVTLIEAGPCR ITQLK----NDD----T--DGY--SAVQIGF-------GE--LINK----------PAQGHLN----------------- ---SG-EGLLRHLREYRV--------DSVEGL-----EI---GG-AITV--G-D-FEAGQKVDVSGDTVGRGFAGYQKRH GFSR-GPMTHGS-KNHR-EPGSTG-AGTTPG-RIYPGKRMAGRYGGKKITTRGLTILKVDSEHN---------------- ----------LLVVKGS-VPGKPGALLNIR-------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----SLKKRYRETI----QPKLQKDLSLTNIHEVPKVVKVTVNRGLG-EAAANAKSLEASVNELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGDRMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARSDEEGRALLREMGMPFQSRIG-K--NPVPVPEKVTVS-L--- -D-G--L-TVKVKGPKGELERTL--PE-G--VSVSQDN-NT--IVV---SP-T--STKRISR-ERHGLSRTLVANMIEGV SNGYSKALEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEMEA-P-E-GITFKVE--N-NTRVIVSG-IDKELVGNEA AKVRAIR------PPEPY---KGKGIKYEGERILRKAGK----------MIQQESYLTVADNSGAKRIQCIRVLGT-NRR Y--AHVGDVIVAAVKDAAPN-M-------GVKKSDVVKAVVVRTKATMRRETGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERSFTKIVSLAPEVIMT-LRLDSLKSNKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSG---R--P TRPGF-E-GGQMPLYRRVPKLKH--FPLLNVSALVNLDSLVKD-GIVTLK---------MLG--NGE-L-K-AKK-LTV- QAAAFTASARAKIEAAGGTCEKFRKQQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGDE ITPEIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHI---TGTSDRPRLAVFRSNNHIYAQVIDD---A--AQSTL CSASTV-DKEL-RTGL---KAPA-GSCDASVAVGELVAKR--AIAKG-IQQVVFDRGGNLYH--GRIKALADAAREAGLQ F--------------------------------------------------------------MT-Q-AHGRFIRGSVSK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPSSLVISSATADMGPSMKRYRPRAQGRAYQIKKQTCHISIAVAAKMRIRKGDTVQVIAGK------DK-GKT GAVLRTLPNEN--RVV--VEGVNMRTRHEK----PT--QE-GET-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---RLKKTG---EVLD-MGHKINPTGLRLG--IT-QEHRSRWYA------SSK N--YPALLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEDLRSGIQKTVR INVVEVER---VDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTKI-PASRMTRSIAKVLQQEGFISEIS EQG----E---G----VRTELVLALKYS--GKHR-------L---PTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARREGVGGEVLCYVYMAQQKIRIRLKAFDRRMLDLSCEKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALVKLDLPSGVDIEVKLVKERIGTVVSDKMEKTVVVAVESRFPHPIYQ KTVSRTTRYKAHDED--NTCRVGDRVRITETRPMSRQKRWAIAEVLSHS------------------------------- -MGRSLK-KGPFIAD-SLLRKVEKQND---NDDKS----VIKTWSRASTILPMMIGHTIAVHNGRTHVPVFITE-QMVGH KLGEFAPTRTFKGHI------R---DK----KGG------R- >CYANO_Cyanothece_sp_PCC_7425 Concatenation of 2 sequences MGIRNYRPYTPGTRQKSVSDFSE-ITHD------------QP-EKSLTSFRHRAKGRNNRGVITSRR-RGGGHKRL---- YREIDFR-R--NK-LSVPGTVLTVEYDPNRNARISLVQYE-DGEKRYILHPRNLAVGAVIAAGP-D-AA-IEVGNALPLS KIPLGTGVHNVEITPGRGGQMVRAAGAMAQVVAK--EGDMVTLKLPSGEVRLFRKECYATIGQIGNVDVNNISIGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGYKTR-KKKKLSN-A-LIVRRR --------------------------------MAV---G-ILGTKLGMTQIFD-QERR---------AIPVTVVQAGPCP ITQIK----TKQ----T--DGY--AAIQVAF-------GE--VLSK----------AELGHLK----------------- ---SN-TAPMRHLHEYRT--------GEVDQF-----QV---GQ-VLKA--D-L-FSAGQVVDVTGTSIGRGFAGYQKRH NFKR-GPMAHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGQLGSARTTIRQLTIVRVDPERN---------------- ----------LVLIKGA-VPGKPGALVSIT-MVACVIKD-WQGSEV-GETALELRVA----KA-EN-AAHIVHRALRRQM ANARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---NR-SP----LW---- RGGGVIFGPK-P-RDYSIKMNYKERRLALRTALISRSDS-------------------LIVVEDF--SDKLP-R------ --PKTKLLI--VADKQ--D---TIYLSARNIATVK-L---------------IQATSLNVFDLLNADW----IVATVEAL GKIQQRLKTYYLENA----VPKLMEQFKYKNIHQVPKLVKITINRGLG-EAAQNAKSLEASLNEIALIAGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRSDRMYAFFDRLINLALPRIRDFRGVNP-KSFDGRGNYSLGLREQLIFPEIS-----YDSI DQMRGMDVSIITT-----------------------ATTDEEGRALLKVMGMPFMSRIG-K--RPIPIPDKVAVT-I--- -D-G--S-TVKVKGPKGELSQVL--PP-E--VVVVQEN-SS--LLV---NR-R--DDSRPAR-QRHGLSRTLVANMVKGV TEGFRKNMQIVGVGY--RLQVTG-NK--LAIT--AGYSHPVEIDL-P-K-GISVEVDQKAVPINFGVIG-IDKQAVGDVA ALIRAVR------PLEPY---KGKGIRYATETLRLKAGK----------MIQQESYLNVADNSGAKKLLCIRVLG-GNRR Y--GSVGDVIIATVKDATPN-M-------PVKKSDVVRAVIVRTRKAIRRESGMSIRFDDNAAVLIN-QDGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--ADAQPNPTS-RRRRRRIG-RGISAGQ-GASGGFGMRGQKSRSG---R--P TRPGF-E-GGQNPLYRRIPKLKH--FPLINVGSLVSLSSLIDA-GIITLK---------VLG--DGD-L-T-V-K-LQV- EAAGFTQAAEAKITAAGGSC-K---QQR--GRM---EGAA-TRGNTLTFG----------DYGLQAL--EPAWITARQIE AGRRAMTRYI------RRGGKIWIRLFPDKPVTMRPAETRMGSGK---------GAPEFWVAVVKP-GRIMYEI--AG-- VSEEVAREAIRLAAYKMPIKTKF-IRVESTRSRHRRVRRKV---GGTGDRPRLAVFRSHQHIYAQVIDD---Q--QQHTL VAASSL-EPEF-KTQY----GEG-DTCAASTQIGKLIAER--SLAKG-IQKVVFDRGGKLYH--GRVKALAEAAREAGLE F-------------------------------------------------------------QPG-AYATARYIRMSPHK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- EHNE-GLNPTDLVVSQAYADQGPSLKRFRPRAQGRAYPIRKPTCHITIAVSPRMHVKKGDTVQVIAGK------DK-AKV GEVLAAFPKTS--NVI--VKGVNIQTKHVK----PQ--RE-GES-GQIVTREAPIHSSNVM-LYSTKQ-------NV--A --SRICYTF---NE--------QGKVR---MLKKTG---EII--MGQKIHPTGFRLG--VT-QEHRSRWFA------DPE R--YPELLQEDHKIRKFIATPHKFKDGNLDSAGIAEVRIERKA-D-QIDLEVRTARPGVVVGRGGSGIELLRTRLQQHIR VNVVEVQR---VDAEAGLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-GIEGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYRTARTVYGILGIKVWVFMATSDTIGDMLTRIRNANLARHPTTEV-PATRMTRSIAQVLKNEGFINDFE EIG----D---G----VKLNLVISLKYR--GKQR-------Q---PTITALKRISKPGLRVYSNRRELPRVLGGIGIAII STSSGIMTDRDARRSGVGGEVLCYVWLQQQKIRIRLKAFDHRLLDTSCEKIVDTAKRTSASAVGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSPKTIDALMKLDLPAGVDIEVKLVKERVGLVVSDKMQKTVVVAVENRAPHPKYG KIVVQTRRYKAHDEE--EKCQVGDRVRIQETRPLSRTKRWVVTDILTSA------------------------------- -MARSL-KKGPFVAD-HLLSKVEALNA---RGERQ----VIKTWSRASTILPQMIGHTIAVHNGRQHVPVYVTE-QMVGH KLGEFAPTRTFRSHT------K--GDK----KAR-Y------ >ACTINO_Acidimicrobium_ferrooxidans_ICP,_DSM_10331 Concatenation of 2 sequences MGIRKRKPTSAGRRFQSSSDFAE-ITKQ------------RP-ERSLVRPLSGSGGRNADGHKTARH-RGGGHKRQ---- YRVVDFR-R--KK-DGVPATVAAIEYDPNRNARIALLHYH-DGEKRYILAPKGLTVGMKVSSGP-D-AD-ITVGSALPLR NIPVGTTVHNVELRPGQGGKLARSAGMGIQLVGK--DEVYATLRLPSTEMRRVPIDCRATVGEVGNAEAELISIGKAGRN -RWR-----GVR-P-QTRGVAMNPVDHPLGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-RRHLPSD-K-LIIRRR --------------------------------MAR---KTFVGEKVGMTQVWT-EGDR---------AVPVTVIKVVPTW VVRTK----TPE----R--DGY--EAVQVAV-------GR--VLSR----------PVAGQFE----------------- ---ARGVEAGARIMELRL--------DGASSF-----EP---GD-QIGI--E-G-IEPGMRLDVVGVSKGHGFSGGMKRH NFRG-QGAAHGNHKKHRA-PGSIGAC-ATPA-RVFKGTRMAGQYGTERVTIHNLEVVRAEPERQ---------------- ----------LVLVKGS-IPGPRGAIVVVR-MASAKVID-ATGRTL-REEELPGEVF----AH-AP-NIALLHQVVVAEQ AGARRGTHSTKTRAE--------VA-GGGAKPY---------RQKGTGNAR--------QGS---IR-AP----QY---- KGGGIVHGPK-P-RDYSQRTPRKMLRAALAQALSDRASAG----------------V-IYVLEDD----VIT-A------ --PSTKLAL--VAGAD--E---AVFKSVRNLPTVR-V---------------HRAGLVLVSAVLASDA----VLFTRAAL AELLPRLRVRFDEEV----RPALFRDLGLENVNQVPRLAKIVVNMGVG-RASAQPSLLEGAVRDLETITGQRPSIRRARK SIAGFKLREGMAIGATVTLRGDRMWEFYDRLVAVAIPRIRDFRGLNP-RSFDGHGNYTFGVTEQLIFPEID-----YDSV DTTRGMDITIVTT-----------------------ATTDAHGRALLEALGFPFMSRIG-R--QPIAVPGGVEVA-V--- -D-G--Q-HVSVRGPRGSLARDL--PP-E--VTVSVVD-SV--VHV---ER-S--DDSRRAR-AMHGLSRTLVANMVRGV AEGYEKTLEIIGTGY--RAQARG-TGE-LELA--LGFSHPVVVEA-P-D-GIAFATP--T-PQRVVVSG-IDKELVGQVA ANIRRIR------KPEPY---KGKGVRYLGERVVRKAGK----------MIQQETRLKVADNSGAREVLCIRVLG-SRRR Y--ASIGDVFVATVKDALPG-A-------AVKKGDVVKCVVVRTRKEVRRPDGSYIRFDDNAAVLIN-DQLQ-PRGTRIF GPVGRELR-DKRFMRIVSLAPEVIIY-L--HDLKPAEGS-HHRKRRVG-RGIAGKG-GKTAGRGTKGQGARDT---V--- -PVGF-E-GGQLPLTQRTPKLRG--FRNVNLDQLVDPTSLVAR-GVVRVK---------VCA--RGE-L-H-A-P-LVV- RAHGFSQAAKAAIEAAGGRV-K---VQR--GRL---GGEA-KGGTEITFG----------RYGIQAL--EPAWVTARQIE AARIAMTRHV------RRGGKVWIRIFPDKPITKKPAETRMGSGK---------GNPEFWVAVVKP-GRILFEL--DG-- VGEELARAAMERAIQKLPMKARF-VREDRRRRRHARVRRRV---VGTSERPRLAVFRSNRHIFAQIIDD---T--AGRTV AAASTV-EPEL-RD------GRT-GSTEGAASVGRLVASR--ALALG-VRRVVFDRGGFQYH--GRIAALADAAREAGLE F-------------------------------------------------------------RPR-SRAVLRNYGASASK VREVLGIIRGKPVEQAIRELSLV---------------------------------SRGPAEAVGKLLASAVAN----A- TVQH-GLGVSDMVVRLAYADEGTTLKRFRPRARGRATRIRKRTCHITVVVEE-MRIRKGDRVRVIAGK------WR-GAE GEVLRALPARH--RVV--VDGVAVAKRHTK----AR--DA-SSP-SGILEKTLPIDVSNVM-IICRAC-------GP--- --TRIAMKV---DD--------AGRQR---VCRRCG---GAL--MGQKVHPYGFRLG--VT-TDWKSRWYA------D-K D--YQRWLIEDEQIRQWL--QRELR-----TASVSRVDIERTR-D-RVRVDIHTARPGIVIGKKGVEVERLRRELERRVQ LNVEEIRQ---PDLDATIVAQSIADQISRRVSFRRAMKRAIQVAMKE-GARGITAQCSGRLGGAEMARRETHREGRVPR- -HTLRADIDFGLREARTTYGQIGVKVWIYMAMTDPIADMLTRIRNASRARHASVTM-PSSKLKVEIARILKREGFIQDYA ERE---SA-V-G----PRKDLVIELRYV---GDR-----RAS---SAIHGIERISKPGLRVYRQAGSLERVLGGMGIAVV STSHGLMTDREARARRVGGEVICHVWSSKQRIRVRLKGFDHEILEASTRRIVDTVTRTQGKVVGPVPLPTDIHRYTVIRS PHKYKDSR-EHFEMRVHKRLLDIVDHSAKTVDALKRLELPAGVDIEIKIRKVREGIVASAKMDKTIVVEIHQRVRHPRYQ RTIARRRRLYAHDPA--NEAREGDRVEIAETRPLSRLKRWRLVRIVERA------------------------------- -MPRSV-SKGPFVDA-HLLKKVDELNA---SGDKR----VIKTWSRRSTIIPDMVGHTIAVHDGRKHVPIYVTE-SMVGH KLGEFAPTRTFRFHA------G--QEK----TAR------RR >ACTINO_Acidothermus_cellulolyticus_11B Concatenation of 2 sequences MGIRKYKPTTPGRRGASVADFVE-ITRE------------HP-EKSLVRPLHSKGGRNVYGRITTRH-QGGGHKRA---- YRLIDFK-RA-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYILAPARLAQGDVVESGP-G-AD-IKPGNNLPLR NIPVGTVVHAIELRPGGGAKIARSAGASVQLVAK--EGMYAQLRMPSGEIRNVDIRCRATVGEVGNAEQSNISWGKAGRM -RWK-----GKR-P-SVRGVAMNPIDHPLGGGEGKS-S--GGRH-PVSP---WGKPEG--RTR-RKHKPSD-K-LIVRRR --------------------------------MPKQVKG-LLGEKLGMTQVFD-ESGR---------VIPVTVVRAGPCV VTQVR----TPD----R--DGY--SAVQLGY-------GA--VVNK----------PLAGHFA----------------- ---AG-VTPRRYLAEVRT--------GDAAEY-----TV---GQ-EVTV--E-I-FTPGQRVDVAGVSKGKGFAGLMKRH NFRG-LPDSHGTERKHRS-PGSIGAC-ATPG-RVFKGLRMAGRMGGRRVTVQNLAVQAVKPEEN---------------- ----------LLLLQGA-VPGPNGGLVYVR----MTTVT-VAGTDR--TVELPADVF----DV-QV-NVPLIHQVVVAQL AAARQGTHKTRTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---IR-AP----QF---- TGGGVVHGPM-P-RHYDQRTPKKMKAAALRGALTDRARAG----------------R-IHVLPRI--VDGEA-------- --PSTKLVV--LDRGD--E---TGWKSLRNIPDVH-L---------------LVADQLNAYDVLSSDD----VVFTEQAL SEFLPRLKQYYREHV----VPALREQFGYRNVMQVPTLVKVVVNMGVG-EAARDAKLIEGAVRDIAAITGQRPAIARARK SIAQFKLRAGMAIGAYATVRGDRMWEFLDRMLTLALPRIRDFRGLSP-KQFDGHGNYTFGLTEQVMFHEVD-----QDKL DRFRGMDITVVTT-----------------------ARTDDEGRALLRHLGFPFMSRIG-R--LPIPVPAGVDVT-I--- -D-G--R-TVTVKGPRGTLTHTI-AEP----ITVEKAEDGT--LHV---RR-P--DDENRTR-GLHGLTRTLIANMITGV TQGFAKTLEIVGTGY--RVQARG-SD--LEFA--LGFSHPVVVRP-P-E-GISFEVQ--T-PTRFVVHG-IDKQKVGEVA ANIRKLR------KPEPY---KGKGVRYQGENVRRKVGK----------MIQQESRLKVADNTGAREILCIRVLG-SGRR Y--AGIGDVIIATVKDALPG-A-------GVKKGDVVKAVVVRTAKERRRPDGSYIKFDENAAVLIK-DGGD-PRGTRIF GPVGRELR-EKKFMRIISLAPEVLLK-P--HHLRPAPGA-HTPKTRVG-RGEGSK--GKTAGRGTKGTKARHT---V--- -PARF-E-GGQMPLHMRVPKLKG--FRNVNVGRLVTPADLVRR-GAVRVK---------ILG--DGD-V-T-V-A-LHV- TADAFSLSAKAKIEGAGGSI-K---QHH--PKR---SGVA-KGGTRVVFG----------EYGIQAL--EPAYVTNRQIE SARIAMTRHI------RRGGKVWITIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVMFEL--AG-- VPEPVAREALRRAMHKLPMKCRF-VRTAARMRRHFRVRKKI---SGTPERPRLVVHRSARHVFVQIVDD---T--RGHTL ASASSF-EPEM-RSFA------G-DKTAKARRVGQLIAER--AKAAG-ITTVVFDRAGYRYH--GRVAAIADGAREGGLV L-------------------------------------------------------------VVR-ARARLRYSTITPMK ARRVVDLVRGLPADEALTTLQFL---------------------------------PQAASATVYKVLASAIANAQQEA- AKQGERLDAEDLVVSAAYVDEGPTLKRFRPRAQGRAYRIRKRTSHITIHVESGLKVRKGDTVQVIAGK------DR-GTK GKVIAAFPREQ--KLL--VEGVNRVRRHTK--VTAT-TRG-SKT-GGIITKEAPIHVSNVM-VVCPEC-------EK--P --TRLGRRQVVDAS--------TGKTR-PRICKRCG---KEI--MGQKVNPHGFRLG--IT-TEFSSRWYA------D-R M--YRDYVKEDVAIRRMM--TRGME-----RAGISRVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRADLEKLVQ LNILEVKN---PEIDAQLVAQGVAEQLSQRVSFRRAMRKALQSALKA-GAKGVRVQVAGRLGGAEMSRTEFYREGRVPL- -HTLRADIDYGFYEARTTFGRIGVKVWIY-MMTDPIADMLTRVRNANSAYHDTVVI-PYSKIKANIAEILQREGYIAGYR VDP----V---P-GHATAKNLVITLKYG---PNR-------E---RSISGVRRVSKPGLRVYAKAENLPRVLGGLGIAII STSAGLLTDRQCAKRRIGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSARKIVETVTRTGARVAGPVPLPTEKNVYCVIRS PHKDKDSR-EHFEMRTHKRLIDIIDPTPRTVDSLMRLDLPAGVDIEIKLRKVREGVVVSDKMDKTIVVAVEDRVKHPLYG KVMRRTSKLKAHDEQ--NTAKVGDRVLLMETRPLSATKRWRLVRIVERA------------------------------- -MPRSL-KKGPFVDD-HLLKKVEAQNA---RGTKN----VIKTWSRRSMIVPEMIGHTIAVHDGRKHVPVFITE-AMIGH KLGEFAPTRTFRGHV------K--EDR----RSR------RG >ACTINO_Actinosynnema_mirum_101,_DSM_43827 Concatenation of 2 sequences MGIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNASGKITTRH-KGGGHKRA---- YRLIDFR-RT-DK-DGIPAKVAHIEYDPNRTARIALLHYV-DGEKRYIIAPAKLHQGDVIENGP-K-AD-IKPGNNLPLR NIPVGTVVHAIELRPGGGAKIARSAGASVQLVAK--DGPYAQLRMPSGEIRNVDVRCRATIGEVGNAEHQNINWGKAGRM -RWK-----GKK-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---AGKPEG--RTR-R-RKASD-R-LIVRRR --------------------------------QVK---G-LLGTKLGMTQVFD-ENNR---------VVPVTVVKAEPNV VTQVR----TQE----N--DGY--SAVQLAF-------GA--IVIK----------PVAGHFK----------------- ---AG-VTPRRHLAELRT--------TDASEY-----QV---GQ-EITA--E-V-FEAGAVVDVVGTSRGKGYAGVMKRH GFAG-LGASHGTQRKHRS-PGSIGGC-ATPG-RVFKGLRMAGRMGHARVTTQNLKVFRVDAESG---------------- ----------LLLIKGA-VPGPKGGTVFVKMTTSVEVRT-PDGKTD-GSVELPGAVF----DA-QA-NISLLHQVVVAQQ AAARQGTHKVKTRAE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPV-P-RDYSQRTPKKMKAAALRGALSDRARAN----------------Q-VHVVTGF--VEGDK-------- --PSTKLVV--LLRDE--D---VSWVSLRNLTHVH-V---------------IAPDQLNTYDVLVNDD----VVFSKSAL DVFLPRLKTRYREEI----AAELQKQFEYANVMQIPGVVKVVVNMGVG-DAARDGKLIEGAVRDLSIITGQRPEVRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLLTIALPRIRDFRGLSG-KQFDGNGNYTFGLNEQSMFHEID-----PDAI DRPRGMDITVVTT-----------------------ATNDEEGRALLKHLGFPFMSRIG-K--LPITVPSGVDVN-I--- -D-G--Q-AVSVKGPKGTLNLTI-AEP----ITLEKADDGT--LEV---KR-P--NDERRSR-SLHGLSRTLVQNMVVGV TQGYEKKMEIHGVGY--RVALKG-SD--LEFA--LGYSHPVKVEA-P-A-GITFAVE--T-PTRFSVAG-IDKQLVGEVA ANIRKLR------KPDPY---KGKGVRYSGEKIRRKVGK----------MIQQESRLRVADNTGAKEILCIRVLG-SGRR Y--AGIGDIIVATVKQAIPG-A-------GVKKGDVVKAVVVRTVKEKRRPDGSYIRFDENAAVLIK-NDNE-PRGTRIF GPVGRELR-DKKFMKIISLAPEVLIK-I--HDLRPAPGA-KTKKTRVG-RGEGSK--GKTAGRGTKGTGARKN---V--- -SPRF-E-GGQMPLHMRLPKLKG--FRNVNVSDLVDVDALITA-GLVRVK---------VLG--DGD-I-NGV-K-LDV- VANKFSGSAVEKIAAAGGTT-K---QHH--PGR---SGAA-KGGTRVTFG----------EFGIQAL--EPAYVTNRQIE SARIAITRHI------RRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANIKP-GRVLFEM--SF-- PNEATAREALRRAIHKLPMKCRI-VRRIAKTRRHFRLRKKV---SGTAERPRLVVHRSSKHITVQIIDD---L--AGHTL AAASSV-EADV-RA------LDG-DKKARAAKVGQLAAAR--AKDAG-ISKVVFDRGGNAYH--GRIAALADAAREAGLE F-------------------------------------------------------------HPR-AVARARYVRDTPMK VRRVVELIRGRSASEALAVLQFA---------------------------------PQAASEPVRKVLASAVAN----A- ENNL-SLDPDTLWVSKVYVDEGPTLKRFRPRAQGRAYRIRKRTSHITVEVES-MKVKKGDTVVVIAGK------DK-GAR GKVIQAYPALD--RVL--VEGVNRIKKHTR-ITQTQ--RG-AQS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRVGYRT---ND-E-------GRVR---ISRRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVAEDVKIRKLL--SRGME-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---PESDAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRSSQVKGIRVQCGGRLGGAEMSRSEHYRDGRVPL- -HTLRADIDYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDKVVM-PHSKLKANIAEILKREGYIASYR DED----G---E----VAKNLVIELKYG---PNR-------E---RSIAGLRRVSKPGLRVYAKSTNLPKVLGGLGVAII STSGGLLTDRQANKQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVREGLVVSDKMDKTIVVAVEDRKKHRRYS KVMRSTAKVKAHDEQ--NAAGIGDRVLLMETRPLSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVLNE---SGKKT----VIKTWSRRSTIIPDMLGHTIAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KSR------RR >ACTINO_Arthrobacter_aurescens_TC1 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFAE-ITRS------------TP-EKSLLRPLHKTGGRNNSGKITTRH-KGGGHKRQ---- YRLIDFR-RH-DK-DGINARVAEIEYDPNRTARIALLHYV-DGTKRYIIAPNKLSQGDFVEAGP-D-AD-IKPGNNLPLR NIPVGTVIHAVELRPGGGAKMARSAGASVQLVAK--EGRFAQLRLPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---NGKPEG--RTR-RPNKESD-K-LIVRRR --------------------------------NVK---G-LLGTKLGMTQVWD-ENNK---------LIPVTVVQADSNV ITQLR----NAE----V--DGY--VAVQIGY-------GQ--IVTK----------PLAGHFK----------------- ---AG-VTPRRHVVELRT--------ADAASY-----EL---GQ-ELSV--E-I-FEAGQKIDVVGTSKGKGFAGVMKRH GFHG-VGASHGAHKNHRK-PGSIGGA-STPS-RVFKGLKMAGRMGAERHTTLNLTVHAIDAEKS---------------- ----------LLLIKGA-VPGARGQVVLVR------------MTST-VKVDLPAEIF----DV-QT-NVPLLHQVVVAQL AAARQGTHKTKTRAE--------VS-GAGRKPF---------KQKGTGRAR--------QGS---IR-AP----HM---- TGGGVVHGPT-P-RDYSQRTPKKMKAAALRGALSDRARNG----------------R-IHVIAEL--VAGTK-------- --PSAKLVV--IERAN--D---VAALSVRNLAGIH-V---------------LYADQLNTYDVLISDD----VVFTKAAF EAFVPRLKTKYAETI----KKSLQDEFSYANVNQVPRLVKVVVNMGVG-DAAKDSKLIDGAVRDLTLITGQKPQVTKARK SIAQFKLREGMPIGAHATLRGDRMWEFVDRLVSLALPRIRDFRGLNG-KQFDGNGNYTFGLTEQVMFHEID-----QDSI DRVRGMDITVVTT-----------------------AKTDDEGRALLKALGFPFMSRIG-R--LPITVPAGVEVK-L--- -D-G--S-VISVKGAKGELSHTV-ASP----IEVTQEE-NT--LTV---TR-P--NDERNSR-SLHGLTRTLIANMIQGV TEGYEKKLEIVGTGY--RVQAKG-SD--LEFA--LGYSHPVNVSA-P-E-GITFVVE--G-PTKLSVAG-INKQQVGEVA ANIRKLR------KPDPY---KGKGVRYAGEVIRRKVGK----------MIQQESRLKVADNTGAKEILTIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTKKERRRADGSYIKFDENAAVILK-NDGD-PRGTRIF GPVGRELR-DKKFMKIVSLAPEVLLK-V--HHLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---V--- -KAGF-A-GGQLPLHMRLPKLRG--FKNVNLEKLVTVESLVEK-GAVRVK---------VLG--TGD-I-T-V-K-VDV- TAHAFSSSAAEKIAAAGGST-K---QHH--PGR---SGAA-TGGTKVSFG----------EYGIQAL--SPAYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SG-- VNEEVAREALRLAIHKLPLKARI-VKSAARSRRQLRIRKRI---TGTAVRPRLVVNRSARHVFVQVVDD---S--KGVTV AYASTL-EADL-RAFD------G-DKTAKAKRVGELVAER--AKAAG-VEAVVFDRGGNKYH--GRIAAVADGAREGGLA L--------------------------------------------------------------ME-AKAIARHIRVTPMK ARRVVNLVRGKQANEALAILKFA---------------------------------PQAASEPVFKVLQSAMANARVLA- DRDGVAFDDSDLFITEAFVDEGPTMKRFQPRAQGRAYRIRKRTSHITLVVATMAKIKKGDLVQVITGAKQERGGDR-GKQ GKVLRVFPDTN--RVL--VEGINRVTKHSK-VGQSQ--RG-TKT-GGIEVVEAPIHVSNVA-LVDPST-------KK--P --TRVGFRL---DT--VEK---DGRIR---VSKATG---KDI--MGQKVNPHGFRLG--IT-TDHVSHWFA-DSTKPG-Q R--YKDFVREDIKIRQLM--STGME-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---PEMEAQLVAQGIAEQLTSRVAFRRAMKKAMQSAQRA-GAKGIRVACSGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFYEAKTTFGRIGVKVWIYMTMTDPVADMLTRLRNANSAYHDTVSM-PYSKLKARVADILKAEGYIAGWK EED----A---E----VGKKLTIDLKFG---PNR-------E---RSIAGVRRISKPGLRVYAKSTNLPHVLGGLGIAIL STSSGLLTDKQAGKKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDVSARKIVETVTRAGATVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKLRKTRRGYVVSDKMEKTIVVQVEDRVKHALYG KVIRRTSKIKAHDEE--NTAGIGDLVLISETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDQ-HLFVKVAREND---KGTKN----VIKTWSRRSMIIPDMLGHTIAVHDGRKHIPVFVTE-SMVGH KLGEFAPTRTFRGHV------K--DDR----KGK------RR >ACTINO_Arthrobacter_sp_FB24 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFTE-ITRS------------TP-EKSLVRPLPKKGGRNNTGKITTRH-KGGGHKRQ---- YRLIDFR-RH-DK-DGVDARVAEIEYDPNRTARIALLHYV-DGTKRYIIAPNKLSQGDFVEAGA-N-AD-IKPGNNLPLR NIPVGTVIHAVELRPGGGAKMGRSAGASIQLVAK--EGRFAQLRLPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---NGKREG--RTR-RPNKESD-K-LIVRRR --------------------------------NVK---G-LLGTKLGMTQVWD-ENNK---------LIPVTVVQADSNV ITQLR----NAD----V--DGY--VAVQIGY-------GQ--IVTK----------PLAGHFK----------------- ---AG-VTPRRHVVELRT--------ADAAEY-----EL---GQ-ELSV--E-V-FEAGQKIDVVGTTKGKGFAGVMKRH GFHG-VGASHGAHKNHRK-PGSIGGA-STPS-RVFKGMKMAGRMGAVRHTTLNLTVHAVDVEKS---------------- ----------LLLIKGA-VPGARGQVVLVR------------MTST-VKVDLPAEIF----DV-QT-NVPLLHQVVVAQL AAARQGTHKTKTRAE--------VS-GAGRKPF---------KQKGTGRAR--------QGS---IR-AP----HM---- TGGGVVHGPT-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHVVAEL--VAGTK-------- --PSAKLVV--IERAN--D---VAALSVRNLADVH-V---------------LYADQLNTYDVLVSDD----VVFTKAAY EAFVPRLKTKYADSI----KSTLIEEFKYENVNQVPRLVKVVVNMGVG-DAAKDSKLIDGAVRDLTLITGQKPQVTKARK SIAQFKLREGMPIGAHATLRGDRMWEFLDRLVTLALPRIRDFRGLSG-KQFDGNGNYTFGLTEQVMFHEID-----QDSI DRVRGMDITVVTT-----------------------AKTDDEGRALLKALGFPFMSRIG-R--LPITVPAGVEVK-V--- -D-G--S-VVSVKGSKGELSHTV-ASP----IEVSLED-GT--LTV---AR-P--NDERASR-SLHGLTRTLIANMIQGV TAGYEKKLEIVGTGY--RVQAKG-SD--LEFA--LGYSHPVNVSA-P-N-GITFAVE--T-PTKLSVSG-ISKQQVGEVA ANIRKLR------KPDPY---KGKGIRYAGEVIRRKVGK----------MIQQESRLKVADNTGAKEILTIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTKKERRRADGSYIKFDENAAVILK-NDGD-PRGTRIF GPVGRELR-DKKFMKIVSLAPEVLLK-V--HHLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---I--- -KAGF-A-GGQLPLHMRLPKLRG--FKNVNLDKLVTVENLVEK-GAVRVK---------VLG--TGD-I-T-V-K-VDV- TVHAFSASAAEKIAAAGGST-K---QHH--PGR---SGAA-TGGTKVSFG----------EWGIQAL--SPAYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVSNVKP-GRVLFEL--SG-- VSEEVAREALRLAIHKLPLKARI-VKSASRSRRQLRIRKRI---SGTAVRPRLVVNRSARHVFVQVVDD---T--KGLTV ASASTL-EADL-RAFD------G-DKTAKAKRVGELVAER--AKAAG-IEAVVFDRGGNKYH--GRIAAVADGAREGGLS L--------------------------------------------------------------ME-AKAIARHIRVTPMK ARRVVNLVRGKQANEALAILKFA---------------------------------PQAASEPVFKVVQSAISNARVLA- DRDGVAFDEGDLIISEAFVDEGPTMKRFQPRAQGRAFQIKKRTSHITVVVATMAKIKKGDLVQVITGAKAERGGDR-GKQ GKVLRVFPDTN--RVL--VEGINRVTKHTK-VGQSQ--RG-TKT-GGIEVVEASIHISNVA-LVDPST-------KK--P --TRVGFRT---ET--VER---NGRVR---VAKSSG---KDI--MGQKVNPHGFRLG--IT-TDHVSHWFA-DSTKAG-Q R--YKDFVREDIRIRQLM--STGME-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---PEMEAQLVAQGVAEQLTSRVAFRRAMKKAMQSAQRA-GAKGIRIACSGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFYEAKTTFGRIGVKVWIYMTMTDPVADMLTRLRNANSAYHDTVTM-PYSKLKARVADILKAEGYIASWK EED----A---E----VGKKLTLELKFG---PNR-------E---RSIAGVRRISKPGLRVYAKSTNLPHVLGGLGVAIL STSSGLLTDKQAGKKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDVSARKIVETVTRAGATVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKLRKTKRGYVVSDKMEKTIVVQVEDRVKHALYG KVIRRNTKIKAHDEE--NTAGIGDLVLLAETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDQ-HLFVKVDRENE---KGTKN----VIKTWSRRSMIIPDMLGHTIAVHDGRKHIPVFVTE-SMVGH KLGEFAPTRTFRGHV------K--DDR----KGK------RR >ACTINO_Atopobium_parvulum_IPP_1246,_DSM_20469 Concatenation of 2 sequences MAVRHLKPTSAGRRFQTISDFVE-ITTD------------KP-EKSLLEPLPKKAGRNNNGRITTRH-QGGGHKRQ---- YRRIDFK-R--RK-DDIPAKVATVEYDPNRSARIALLHYA-DGAKAYILCPEGLSVGDTVLSGTKD-VD-IKPGNCTTLE QIPVGTLVHAVEFQPGKGAAMARAAGTSVQLMGK--DNGYAVLRMPSSELRRVLLTCRATIGEVGNAEHSNIVVGKAGRS -RWA-----GVR-P-TVRGTVMNPVDHPHGGGEGKNHT--SGRP-SVTP---WGKPTKGYKTR-DPKKASN-R-LIIRRR --------------------------------MVN---T-ILGRKLGMTQVWD-ENDN---------VVPVTVVLAGPCT VSQVK----TVE----T--DGY--NAVQIGF-------GD--IVNK----------PMAGHFK----------------- ---AQGVEPMRYLREVRV--------EDASEH-----KT---GD-VVTV----ADFSEVTTVDVTGTSKGKGFQGTVKRW NFSR-GPMTHGS-RNQRR-PGSIGQC-AYPA-RVRKGLHMYGHMGAERVTVKNLKLVRVDAEQN---------------- ----------LMLIKGA-VPGGKNALVQVR-MSKYEIKN-VEGKKV-GTTELSSDVY----GI-EP-NIPVVHQVVVCQD ASARQGTHSTKNRHE--------VS-GGGVKPY---------RQKGTGRAR--------QGS---IR-AG----QW---- TGGGVIFGPT-P-RSHARRINNKMVKLAMRSVLSGKVADS----------------E-LVLVDSL----EFA-Q------ --PSTKTVI--VPDDD--V---NTYLSFRNLPKVS-I---------------FGVSEVTTRFLIDNGA----LVMSADVA KQLGPRLKELYYASV----RDALKEKFGYTNVNQIPKFEKIVVNMGVG-EAATDAKAIDGAVNDLRTITGQQPLVTHARK SIATFKLRQGMPIGAKVTLRGDRMWEFLDRLIAVAIPRIRDFRGIST-KSFDGRGNFSMGVTEQLIFPEID-----FDKV DHTRGMDITIVTT-----------------------ANTNEEGKALLEAFHFPFMSRIG-K--KPVQIPAGVTVT-V--- -D-N--T-TVTVKGSKGELTRTF-TEL----VSIAHEG-EE--ILV---TR-V--DESSESN-AQQGLVRTLIHNMVVGV SEGFEKKLELTGVGY--RVALKG-KD--LDLS--LGYSHPVLYVA-P-E-GISFEVP--D-NTHITVKG-ISKEKVGQVA AEIRMKR------PPEPY---KGKGIHYEGEHIRRKLGK----------MIQMETILNVADNSGARRVKCVKVLG-SKRR Y--AGLADVIIGAVQEATPG-G-------SVKKGDIVRCVIVRTAKDTRRKDGSYIRFDQNACVLVN-KEGE-PKGTRIF GPVARELR-DHKYMKIVSLAPETLMQ-L--NDLRPAVGS-RKNRKRVG-RGNSSGN-GTFAGRGMNGQLSRSGGG-K--- -GAGF-E-GGQQPLAMRLPKLPG--FTNVNVARLVDADTLVAK-GVIKVK---------VLG--DGE-L-S-K-K-LTV- KVDKVSASAKAKIEAAGGKV-K---VQR--GSM---KGQA-KGNTQLHFG----------TWGIRAE--EAHWITNRQIE AARIALTREM------KRGGKVWITIFPDKPITKKPAETRMGSGK---------GNPEEWVAVVKP-GRIMFEI--DG-- VPEEVAREALRLAQHKLPIKTKI-VKKAGLERRKRRVRAKV---FGTSERPRLAVHRSNANIYAQLIDD---A--SGRTL CSASTL-DPEF-RSTG----KVG-SNKEAAEFVGELIGKR--AAEKN-VTEVTFDRGGRLYH--GRVKALADGARNAGLK F-------------------------------------------------------------SIE-VRATAKYVRVAPRK ARAVVALVRGKSVEKALEVLQFS---------------------------------TRAAATDVAKVLRSAVAN----A- ENNN-GLRANNLVVKTAFVDEGPTLKRIRPRAKGSASRINKRMSHITVVVAPKMKIKKGDKVEVLTGK------DK-GKR GEVLRVYPEKN--KVV--VEGVAIVKRHVK----PN--AA-NQQ-GGIVEAEAVIDASNVA-LIDPKT-------DK--P --TRVGYLI---KE--------DGKVR---VSKKSG---AEL--MGQKVQPTGFRLG--VT-ESWRSRWYA------D-K D--YAEQLGNDLAIRKYL--EKRLE-----KAAVARIDIERAG-D-KVKVTIFSARPGIVIGKKGAEIDGLRADLERVVN VDVVEVKR---PELDANLVAQSIAEQLEQRVAFRRAMRKAVQSARKA-GAKGIRIQCSGRLNGAEMGRREWYREGRVPL- -HTLRAAIGYGTATGRTTMGAVGIKVWIYMKITDPISDMLTRIRNANSAGKDSVSM-PSSKVLVEIARVITEEGYVEGYT VED----T---K----PQKTLHITLKYG---KKR-------A---KIIRGIRCISKPGLRIYSTAEKLPRVLGGLGTAVV STSKGMMCDRDARKAGVGGEVIAYVWMSSQKIRIRLKGYDHEVIDQSAKLIVDTAQKTGARVSGPIPLPTERNLYTVIRS PHKDKDSR-DQFEMRTHKRLIDILDPSASTVDSLMRLDLPAGVDIEIKLRKVRTGLVVSISGEKTITVEITYRKHHPKYG KMMTIGKKLHVHDEN--NEAGLGDTVRVMETRPLSKTKRWRLAEIVERA------------------------------- -MSRSL-KKGPFVET-RLLARVAAMNE---AGKKD----VIKTWSRSSTIFPEMVGHTIAVHDGRKHVPVYITE-SMVGH KLGEFSPSRTFRGHK----------TK--------------- >ACTINO_Beutenbergia_cavernae_HKI_0122,_DSM_12333 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-VTRS------------EP-EKSLVRPLSKSGGRNSTGRITSRR-RGGGHKRA---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIVAPNRLKQGDRIENGP-A-AD-IKPGNNLPLR NIPTGTVIHAVELRPGGGAKIARSAGSSVQLVAK--DGPYAQLRMPSGEIRNVDARCRATIGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-SVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPEG--RTR-RPGKPSD-K-LIVRRR --------------------------------SAAAVTA-LLGTKLGMTQVWD-DAGR---------LVPVTVVQVGTNV VSAVR----TPE----T--DGY--SAVQLAF-------GQ--IVTQ----------PLKGHFK----------------- ---AG-VTPRRHVAEIRT--------GDAAEY-----TP---GQ-ELTV--E-V-FAAGQGVDVVGTTKGKGTAGVMKRH GFSG-VGASHGAHRNHRK-AGSIGGA-STPS-RVFRGLRMAGRMGNDRHTVQNLKIHAVDAEKG---------------- ----------LLLVTGA-LPGPRGGLVVVKSTLTVDVID-AKGKKS-GTADLPADVF----DV-QT-NVPLIHQVVVAQL AAARQGTHKTKTRGE--------VR-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPV-P-RDYSQRTPKKMKAAALRGALSDRARAD----------------R-VHVVSGF----VAD-A------ --PSTKLVV--LERTD--T---TAWLSLRNVPAVH-L---------------IHPDQLNTYDVLVSDD----VVFTRGAL EQFLPRLKLRYREEI----RSALKEEFGFANIHQVPGLTKIVVNMGVG-DAARDSKLIDGAIRDLSLITGQKPQVTKARK SIAQFKLREGQPIGAHATLRGDRMWEFLDRLLSIALPRIRDFRGLEP-RQFDGHGNYTFGLVEQSMFHEID-----PDSI DRVRGMDITVVTT-----------------------ASTDDEGRSLLRRLGFPFMSRIG-K--IPVQVPSGVDVD-I--- ---A-DR-VVTVKGPKGTLTHRV-PAP-I--VVARGDD-GA--LVV---TR-P--DDERTSR-SLHGLTRTLLANLVTGV TQGYQKNLEIVGTGY--RVTAKG-SS--LEFA--LGFSHPVTVSA-P-E-GITFAVE--S-PTKFSVAG-IDKQQVGEVA ANIRKIR------KPEPY---KGKGVRYAGEQVRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTAKERRRPDGSYIRFDENAAVLLK-SDGE-PRGTRIF GPVGRELR-DKKFMRIVSLAPEVILK-V--HHLRPAPGA-RTAKTRVG-RGEASK--GKTAGRGTKGSKARGN---V--- -PAAF-E-GGQTPMHMRLPKLRG--FTNVNLGRLVTVADLVAK-GAVRVK---------VLG--TGD-V-D-V-K-LDV- KVDAYSASAKEKIVAAGGSL-K---QHH--PRR---TGAA-SGGTTIAFG----------DYGIQAV--EGGYLTNRQIE AARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSVEWWIANIKP-GRVLFEL--AG-- VDEPLAREAMRRAQHKLPMKTRF-VTATARKRRHLRVRKRI---VGTPERPRLVVTRSSRHIVAQLVDD---S--TGTTL ASASTL-EADL-RA------SDG-AKVDKAHKVGELLAAR--GTAAG-VTTAVFDRGGNAYH--GRVAAVADGAREGGLT L--------------------------------------------------------------ME-AKAQARFVRVTPQK ARRVVDTIRGKGAAEAVAVLSFA---------------------------------PQAAAETVRKVVESAVANARVKA- DTASVRFDPADLVIAEAYVDEGPTLKRFRPRAQGRANQVLKRTSHITVIVAEMAKIKKGDLVVVISG----NRDDR-GKQ GRVLEVLTDSN--RVV--VEGVRRVKKHTK-VSQTQ--RG-SRT-GGIETIEAPIHVSNVM-LVDPET-------KK--G --TRVGYRT---EE--VER---NGRVR---VAKRSG---KDV--MGQKVNPLGFRLG--IT-TDHRSRWFA-DSTKPG-Q R--YRDYVREDVQIRKLM--STGLE-----RAGISKVEIERTR-D-RVRVDLHTARPGIVIGRRGAEADRLRSELEKLVQ LNILEVKN---PELDAQLVAQGIAEQLASRVAFRRAMRKGMQSAQRA-GAKGVRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFFEARTTFGRIGVKVWIY--MTDPIADMLTRLRNANSAYHETVTM-PYSKLKSHIAEILQAEGYIVGWR VED----A---E----VGKHLVLLLKYG---PNR-------E---RSLAGVRRVSKPGLRVYAKSTNLPKVLGGLGVAIL STSSGLLTDRQAATKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVFCVIRS PHKYKDSR-DHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKLRKTRRGYVVSDKMQKTVVVEVEDRVKHPLYG KVIRRTTKVKAHDEA--STAGVGDLVLIMETRPLSATKRWRVVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLQKKVDDQNT---KGTKN----VIKTWSRRSLITPDFLGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTYRGHD------K--DDR----KAR------RR >ACTINO_Bifidobacterium_adolescentis_ATCC_15703 Concatenation of 2 sequences MAIRVYKPTTAGRRNASVSDFSE-LTRS------------TP-EKSLVRKLSKTGGRNSYGRMTSRH-RGGGHKRQ---- YRLIDFK-RW-DK-DGVPAKVAHIEYDPNRSARIALLHYA-DGEKRYIIAPEGIKQGDVIETGA-Q-AD-IKPGNNLPLR NIPTGTVVHAIELRPLGGAKIARSAGAAVQLVAK--DGAYAQLRMPSGEIRNVDARCRATVGEVGNSDHANIQLGKAGRA -RWM-----GKR-P-ITRGESMNPVDHPHG---GRT-R--GGKP-PVSP---WGKGEV--RTR-RPKKASN-K-MIVRRR --------------------------------NRT---A-LLGKKLGMSQVWD-ENGF---------FVPVTLVDVSTNV VTAVK----SEE----S--DGY--KAVQLGY-------GQ--VVTK----------PLAGHFK----------------- ---AG-VTPRRHLAEVRT--------DNAEEF-----EP---GQ-ELTA--E-L-FPEGTLVDVTGTTKGKGFAGTIKRW GFKS-YRRTHGSHKNERR-PGSVGAC-ATPS-RILKGKRMAGRMGHVTNTALNLTIVSSDVENG---------------- ----------VLAIKGA-IPGPKGSIVLVRANVTLNVTD-NQGKAT-GTVDAPAEIFGSAEEV-QS-RIPLIHQVVIAQL AAARQGTHATKTRGM--------VS-GGGRKPW---------KQKGTGRAR--------QGS---IR-AP----QW---- YHGGTVFGPQ-P-RDYSQRTPKKMKAAALKYVLSDRANAG----------------H-VAVV-DF--G-VSE-A------ --PSTKTVV--LSREN--V---NEWLSVRNIPTVH-P---------------IFADQLNTYDVVTAQY----VVFSKEGF DAFLPRLKQKYNEQI----VPELEKEFHYSNPMQVARVQKVVVSMGVG-AAARDSKLIEGAVKDLTLITGQKPKITKAKK SVAQFHLREGQAIGAYVTLRGERMWEFLDRLLTMALPRIRDFRGING-DQFDGQGNYNFGLTEQSMFHEID-----PDSI DHQRGMDITVVTS-----------------------TKDDKEARVLLKHLGFPFASHIG-K--LPVTIPAGVEVK-I--- -D-G--Q-SFTAKGAKGTDSYEI--PE-G--ITAVVEG-NE--VVL----T-P--ADDRPTR-AKHGLARSIVAGMVKGV HEGYAKTLEIVGTGY--RAQMKG-KG--IEFS--LGYSHTITVEP-P-A-GIEFELP--N-PNQVIVKG-IDKQAVGQCA ANIRKLR------APEPY---KGKGIKYADEHILRKAGK----------MIQQETRLHVADNTGAKELLAIRVLG-SKRR Y--AGIGDVIVASVKDAIPG-G-------SVKKGDVVKAVVVRTVKEHRRVDGSYIKFDENAAVILG-SGRE-PKGTRIF GPVGRELR-DKRFMKIVSLAPEVILQ-M--HDLKPAPGA-NKDRIRVG-RGEGSK--GKTSGRGDKGTKKRYQ---V--- -RPGF-E-GGQLPLYMRLPKLRG--FKNVNVAVLITVADLVAK-GAVRVK---------VLG--DGE-V-S-A-A-YTL- KGVKASASAKSKIEAAGGSI-K---QHR--PVR---RGMS-KGGNEIAFG----------DFGIQAL--APAYVTNRQIE AARIAMTRYI------KRGGRVWITIFPDRPLTKKPLGTRMGSGK---------GTPEFWIANVHP-GRVMFEI--GG-- VSEDVAREALRRAIDKLPMKCRV-IKKVALKRRHARLRKHI---SGTPELPRLVVTRSNRHMVAQIIDD---T--KGVTL VSESTL-TSDF-AGFE------G-TKTEAAKKVGELIAKK--AQDAG-ITAVVFDRGGNKYH--GRVAAVAEGAREGGLA L--------------------------------------------------------------ME-AKAIARHVRVTPRK ARRMVDLIRGKKATEAITILKFA---------------------------------PQDASLPVRKVLESAIANARVKA- DKAGEPFRENDLVVKETYVDEGVTLKRFRARAQGRAARINKRTSHITVVVANAAKIKSGDLVKVIRGK------DR-GKE GTVKQVLKDDR---LI--VEGVQIVKKHVR----AT--QQ-GQQ-AGIVAVEAPIHRSNVM-VIDPET-------KQ--P --TRVRIVE---KE-----EARDGRVR---VAKKSG---KEL--MGQKINPFGYRLG--IT-ENHRSKWFS-DSNKVG-E R--YRDFVLEDDAIRKAM--SKDLE-----RAGVSRIVIERTR-D-RVRVDIHTARPGIVIGRRGAEAERVRAKLEKLVQ LNIFEVKN---AALDAQLVAQGIAEQLTNRVTFRRAMRKAQQDAMRA-GAKGIRIKLSGRLGGAEMSRSEFYREGCVPL- -QTLRALIDYGFFEAKTTYGRIGVKVWIYMTMTDPIADMLTRLRNASAAKHETVDM-PYSKFKANIAEILKREGYIKDFT AKE----A---K----VGQTLEVTLKYG---PNG-------E---RSIQGIKRISKPGLRRYAKSDALPMPLGGLGIAII STSSGLLTQKECLDRGIGGEIVAFVWMAGQKIRIRLKSYDHEVIDQSAKKIVETVTNAGATVVGPVPLPTEKNVLVVIRS PHKYKDSR-EHFEMRTHKRLIDIVDPTPKAVDSLMHIDLPADVNIEIKLRKVRRGYVVSDKMDKTISVELEQRSTHPLYG KVVRSTRTVKVHDEH--NEAHIGDLVSIMETRPLSKTKRWRLDSIIERA------------------------------- -MTRSI-KKGPFVDA-HLQKKVDEQNE---KGTHN----VIKTWSRRSMITPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTKTFKGHV------K--DDK----KAR------R- >ACTINO_Bifidobacterium_longum_NCC2705 Concatenation of 2 sequences MAIRVYKPTTAGRRNASVSDFSE-LTRS------------TP-EKSLVRKKSKTGGRNSYGRITSRH-RGGGHKRQ---- YRLIDFK-RW-DK-DGVPAKVAEIEYDPNRSARIALLHFA-DGEKRYIIAPKGIKQGDVIETGA-Q-AD-IKPGNNLPLK NIPTGTVVHAIELRPLGGAKIARSAGAAVQLVAK--DGAYAQLRMPSGEIRNVDARCRATVGEVGNEDHANIQLGKAGRA -RWI-----GRR-P-ITRGESMNPVDHPHG---GRT-R--GGKP-PVSP---WGKGEV--RTR-RPKKASN-K-MIVRRR --------------------------------NRK---A-LLGKKLGMSQVWD-ENGF---------FVPVTLVDVSTNV VTAVK----TEE----S--DGY--KAVQLGY-------GA--IVTK----------PLAGHFK----------------- ---AG-VTPRRHLVEVRT--------DDVDQF-----EA---GQ-ELAA--D-L-FEEGAEVDVTGTTKGKGFAGTIKRW GFKS-YRRTHGSHKNERR-PGSVGAC-ATPS-RILKGKRMAGRMGHVTATTQNLTVVSADVENG---------------- ----------ILAIKGA-IPGPKGGIVLVRANVTLNVTD-AKGQAT-GTVEAPEALFGSAEDV-QA-HIPLIHQVVTAQL AAARQGTHATKTRGM--------VS-GGGKKPW---------KQKGTGRAR--------QGS---IR-AP----QW---- YHGGTVFGPQ-P-RDYSQRTPKKMKAAALRYALSDRANAG------------------RVAVVEF----GIT-E------ --PSTKTVV--FTRDN--I---NEWLSVRNIPTVH-P---------------IFVDQLNTYDVITSQY----VVFTKEAF EAFVPRLKVKYNEQI----IPELEKEFKYSNPMQVARVQKVVVSMGVG-AAARDSKLIEGAVKDLTLITGQKPKITKAKK SVAQFHLREGQAIGAYVTLRGDRMWEFLDRLLTLALPRIRDFRGING-HQFDGQGNYNFGLTEQSMFHEID-----PDSI DHVRGMDITVVTS-----------------------TKDDKEAYALLKHLGFPFASHIG-K--LPIAIPAGVEVK-I--- -E-G-Q--NFSAKGAKGSDSYVV--PE-G--ITAAVEG-NE--IVL---TA-A--DDLRPTR-AKHGLARSIMAGMVKGV HDGYSKTLEIVGTGY--RAVAKG-QG--IEFF--LGYSHTITVNP-P-E-GITLKVT--D-ANHVVVEG-TDKQVVGQVA ANIRKLR------APEPY---KGKGIKYSDERILRKAGK----------MIQQETRLHVADNTGAKELLAIRVLG-SKRR Y--AGIGDVIVASVKDAIPG-G-------SVKKGDVVKAVVVRTVKESRRADGSYIKFDENAAVILG-SGRE-PKGTRIF GPVGRELR-EHKFMKIVSLAPEVILQ-M--HDLKPAPGA-KKDRTRVG-RGEGSK--GKTSGRGAKGQTKRNH---V--- -RPGF-E-GGQLPLYMRLPKLRG--FKNINIARLVAVADLIAK-GAVRVK---------VLG--DGE-T-T-V-A-FTL- KGVKASASAKSKIEAAGGSV-K---QHR--PVR---SGMS-KGGNEINFG----------DFAIQSL--APAYVTNRQIE AARIAMTRYI------KRGGRVWITIFPDRPLTKHPLGARMGSGK---------GAPEFWIANVRP-GRVMFEI--GG-- VSEDIAKEALRRAIDKLPMKCRI-IKKVALKRRHARIRKRI---SGTPERPRLVVTRSNRHMVAQVVDD---T--KGITL VSASTL-QADF-AGFE------G-TKTEAAKKVGELIAEK--AKAAG-ITAVVFDRGGNKYT--GRVAAVADGAREGGLA L--------------------------------------------------------------ME-AKAIARHVRVTPRK ARRMVDLIRGKKATEAVTILKFA---------------------------------PQAAALPVRKTLESAIANARVKA- DKAGEPFRENDLYIKETYVDEGVTLKRFRARAQGRAARINKRTSHITVVVANAAKIKSGDLVKVIRGK------DR-GKE GTVKQVL-SND--RLI--VEGVQIVKKHVR----AT--QQ-GQQ-AGIVSTEAPIHRSNVM-VIDPET-------KQ--P --TRVGITV---KEE-------DGRVR---VAKKSG---KEL--MGQKINPFGYRLG--IT-ENHRSKWFSDSN---KGE R--YRDFVLEDDQIRKEM--SKDLE-----RAGVSRIVIERTR-D-RVRVDIHTARPGIVIGRRGAEAERVRAKLEKLVQ LNIFEVKN---AALDAQLVAQGIAEQLTNRVTFRRAMRKAQQDAMRA-GAKGIRIKLSGRLGGAEMSRSEFYREGRVPL- -QTLRALIDYGFFEAKTTYGRIGVKVWIYMTMTDPIADMLTRLRNASAAKHETVDM-PYSKFKANIAEILKREGYIKDFT AKE----A---K----VGQTLEVTLKYG---PNG-------E---RSIQGIKRISKPGLRRYAKSDSLPMPLGGLGIAII STSSGLLTQKECLDRGIGGEIVAFVWMAGQKIRIRLKSYDHEVIDQSAKKIVETVTNAGATVVGPVPLPTEKNVFCVIRS PHKYKDSR-EHFEMRTHKRLIDIVDPTPKAVDSLMHIDLPADVNIEIKLRKVRRGYVVSDKMDKTITVELEQRSTHPLYG KVVRSTSKVKAHDEH--NDAHIGDLVSIMETRPLSKTKRWRLESIIERA------------------------------- -MTRSI-KKGPFVDA-HLQKKVDEQNE---KGTKN----VIKTWSRRSMITPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTKTFKGHV------K--DDK----KAR-------R >ACTINO_Brachybacterium_faecium_6-10,_DSM_4810 Concatenation of 2 sequences MAIRKSKPTTPGRRGSSGADFVE-VTRS------------TP-EKSLVRPLSKSGGRNNNGRITSRH-RGGGHKRA---- YRVIDFR-RH-DK-DGVRAKVAHIEYDPNRTARIALLHYL-DGEKRYILAPAKLRQGDWIENGA-G-AD-IKPGNNLPLR NIPLGTVVHAIELRPGGGAKIARSAGASVQLVAK--EGPYAQLRMPSGEIRNVDARCRATIGEVGNAEQSNISWGKAGRM -RWK-----GKR-P-HVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQLEG--RTR-RPGKESD-K-LIVRRR --------------------------------KARPVSG-VLGTKLGMTQVWD-ENGK---------LVPVTVVQTGANV VTQIR----SVE----T--DGY--DAVQIAF-------GQ--IVSQ----------PLRGHFK----------------- ---AG-VTPRRHLVELRT--------VNAAEY-----TL---GQ-EIDA--S-V-FEAGQKVDVVGTSKGKGTAGVMKRH GFAG-VGASHGQHRNHRK-PGSIGGA-STPG-RVFKGQRMAGRMGGDRTSVQNLTVHAVDVEKG---------------- ----------LVLVKGA-VPGAKGGLVLVRANLTVDVLD-PAGKKS-GSVELPASIF----DV-QT-NVPLIHQVVVAQQ AAARQGTHKAKTRAE--------VR-GGGKKPW---------KQKGTGRAR--------QGS---LR-AP----QF---- TGGGTVHGPV-P-RDYSQRTPKKMKAAALRGALSDRARNG----------------R-VHVVSSL--LEGDV-------- --ASTKLVV--VRRDD--D---LGALSSRNLPTTH-V---------------LYADQVNTYDVMLSDD----VVFTAGAL EDFVPRLKSKYNETI----KAQLTEQFGYENVMLVPGLTKIVVNMGVG-DAARDSKVIDGAIRDLADITGQKPQVTKARK SIAQFKLREGMPIGAHVTLRNARMWEFLDRLLSTALPRIRDFRGLSP-KHFDGNGNYTFGLTEQVMFHEIN-----QDKI DRVRGMDITVVTT-----------------------AKTDDEGRALLKLLGFPFMSRIG-L--RPVAVPAAVTNVTI--- -E-G--G-TVSVSGPKGELTHEV-PAP----LTVERGEDGT--IVV---RR-P--DEERETK-ALHGLTRTLVNNIVLGV TEGFTKKLEIMGTGY--RVTAKG-TD--LEFA--LGFSHPVVVKA-P-E-GITFTVE--S-PTKFSVSG-IRKQQVGEVA ANIRKLR------KPEPY---KGKGVRYADETVVRKAGK----------MIQQESRLKVADNTGAKEILCIRVLG-SGRR Y--ASIGDTIVATVKDAIPG-G-------NVKKGDIVKAVVVRSSKEVRRVDGSYIRFDENAAVILK-TDGE-PRGTRIF GPVGRELR-DKRFMKIVSLAPEVVLK-L--HDLRPAPGS-KTARTRVG-RGEASK--GKTAGRGTKGTKARYQ---V--- -PLGF-E-GGQIPLHMRLPKLRG--FTNVNLETLVTVEELVAK-GAVRVK---------VLG--SGE-V-S-V-K-LDV- TAQKFSASAEQKIAAAGGSV-K---QHH--PTR---SGMA-KGGTDLAFG----------DYGIQAL--EPAYVTNRQIE AARIAMTRYM------KRGGKVFINIYPDRPLTKKPAEVRMGSGK---------GSVEWWIANIKP-GRVMFEI--AG-- VEEEVAREALRLAQHKLPMKSRI-LKLRARGRRHLRVRRRV---IGTAQRPRLVVTRSARHVFVQVVDD---S--LGKTL VSASTM-EADL-RA------AES-TKSDKARTVGTLVGER--AKAAG-IDSVVFDRGGNKYH--GRVAAVADGAREAGLA L--------------------------------------------------------------ME-AKAQVRYLRMSPMK ARRVVDLIRGKSTAEALNTLRFA---------------------------------PQGASEPVLKLVESAIANARVKA- DQSGERFDERELVVSAAFVDEGPTMKRFQPRAQGRAFQIKKRTSHVTVVVAPTMKIKKGDLVQVITGKRGLEAGDK-GKQ GRVLQVFPDSQ--RVL--VEGINRRTHHVR----PN--QA-GGA-GGIEQREAPLHVSNVA-LVDPED-------NK--P --TKVGYRVTVELE--------NGRVR---FAKRSG---KDI--MGQKVNPNGFRLG--IT-TEHSSRWFA-DSSKEG-Q R--YRDYVKEDVAIRSLM--SKGME-----RAGISKVEIERTR-D-RVRVDLHTARPGIVIGRRGAEAERLRGELEKLIQ LNILEVKN---PEADAQLVAQGIAEQLAARVSFRRAMRKGMQSAQRA-GAKGIRVAVSGRLGGAEMSRNEFYREGRVPL- -HTLRANIDYGFYEARTAFGRIGVKVWIYMTMTDPIADMLTRIRNASGAYHETASM-PYSKLKARIADILKAEGYILGWT EEE----A---E----VGSKLILELKYS---DSR-------E---RAISGIRRISKPGLRVYAKSTNLPKVLGGLGVAIL STSSGLLTDRQAAKKGVGGEVLAYIWMAGQKIRIRLKSYDHEVIDSSARKIVDTVTSAGATVVGPVPLPTEKNVFCVIRS PHKYKDSR-EHFEMRTHKRLIDIVDPTPKAVDSLMRLDLPADVNIEIKLRKTLRGFVVSDKMDKTIVVAVEERVKHARYG KVTTKTSKFKAHDEE--NTAGIGDRVLVMETRPTSATKRWRLVEILERA------------------------------- -MPRSI-AKGPFVDD-HLQKKVDVQNE---KGTKN----LIKTWSRRSVITPDFLGHTFAVHDGRKHVSVFVTE-SMVGH KLGEFAPTRTFKGHE------K--DDR----KGR------RR >ACTINO_Catenulispora_acidiphila_ID139908,_DSM_44928 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-ITRS------------TP-EKSLVVPVHSKGGRNSTGRVTVRH-QGGGHKRA---- YRLIDFR-RN-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYILAPKNLGQGDRIENGP-G-AD-IKPGNNLPLR NIPTGTTIHAIELRPGGGAKIARSAGASVQLVAK--DGPFAQLRMPSGEIRNVDLRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-TVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-KPGKASD-K-YIVRRR --------------------------------MGKQIKG-VLGEKLGMTQVWD-ENNR---------VVPVTVVKAGPCV VTQIR----KQE----I--DGY--EAVQIAY-------GA--VVTK----------PEAGHFK----------------- ---AG-VTPRRYTVEIRT--------TDAAEY-----SL---GQ-EITA--E-T-FTQGQIVDVSGTSKGHGFAGVMKRH NFKG-LGAGHGVQRKHRS-PGSIGAC-ATPG-RVFKGVRMAGRMGSARVTVQNLTVQAVDAEKG---------------- ----------LILVKGA-IPGPNGGLVLVK------------MTQV-VSVDLPGEIF----DV-QT-NIPLIHQVVVAQL AAARQGTHKTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPV-P-RDYAQRTPKKMKAAALRGALSDRARDG----------------R-VIVVDAL--VEGAT-------- --PNTKLVV--LQRTD--E---VSYKSLRNVPTVH-L---------------IDVGQLNTYDVLVNDA----VVFTQGAY DQFVPRMKLRYRSEI----APALKEQFGFPNVMLIPGLTKIVVNMGVG-DAARDSKLMDGAVRDLAAITGQKPTVTRARK SIAQFKLREGQPIGAHVTLRGDRMWEFCDRLVSIALPRIRDFRGLSP-KQFDGRGNYTFGLNEQSMFHEID-----QDKI DRVRGMDITVVTT-----------------------ARNDDEGRALLRLLGFPFMSRIG-R--LPIPVPTGVDVT-I--- -N-G--Q-DVTVKGPKGTLSHTV-VNP----ITIEKGEDGN--LVV---SR-P--NDERIAK-ERHGLSRTLVNNMIIGV TQGYTKSLEISGVGY--RVTAKG-SD--LEFA--LGYSHPVPVPA-P-A-GITFAVE--S-PTRFSVSG-IDKQLVGETC AYIKKLR------KIDPY---KGKGIKFTGEVIRRKAGK----------MIQQESRLRVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDALPG-A-------GVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVLIK-DGGD-PRGTRIF GPVGRELR-EKRYMRIVSLAPEVLLK-V--HHLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---V--- -SARF-E-GGQMPLHMRLPKARG--FKNVNLDKLVTVEDLIAK-GAVRVK---------VLG--TGE-V-S-V-A-LQV- KAHAFSASAKEKLAAAGGSA-K---QHH--PGR---SGAS-KGGNNLAFG----------EYGIQAL--TPAYVTNRQIE SARIAINRHI------RRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEERAREALLRATHKLPLKCRI-IKRNAVKRRHLRVRKKV---SGTALRPRLVVTRSARHMVAQVVDD---V--TRVTL ASASTM-ESGL-RT------GDG-DKTAKAKEVGKLVAER--AKAKG-VGTVVFDRGGNKYH--GRVAAVADGAREAGLE L-------------------------------------------------------------GNE-AIAQAKNIRMTAMK VRRVVDMVRGQDVEQALDTLRFA---------------------------------PYAAAEPVFKCVASAAAN----A- RNNK-QL-RGSLVISEAYVDEGPTLKRFRPRAQGRAYRIRKRTSHITIVVQEGLNIKKGDLVQVITGK------DK-GLQ GKVIQAFPDTE--KVL--VEGVNRVKKHTK---VGQSVRG-SKT-GGIITIEAPIHVSNVM-LVVEHE-------GV--K VVTRVGYRR---VE--EERTLADGSVR---YAKRTG---KDI--MGQKVNPHGFRLG--IT-TDFKSRWYA------D-K L--YKDYVKEDVAIRRLM--TEGMD-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGKLEKLVQ LNILEVRN---PESDAQLVAQGIAEQLAQRVAFRRAMRKAIQSSMKA-GVKGIKVQVSGRLGGAEMSRSEQYREGRVPL- -HTLRANIDYGFYEAKTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDQVTM-PSSKIKTHICEILKQEGYIASWK VED----A---E----VGKSLTIELKFG---PNR-------E---RSIAGIKRISKPGLRVYAKSTGLPKVLGGLGVAII STSTGLLTDRQAARKGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSAKKIVETVIRTGAQVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGYVVSDKMEKTIVVEVEDRKKHPKYR KVVRRTTKLKAHDEQ--NTAGVGDRVLLMETRPTSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDG-HLIKKVDAQNA---KNTKT----VIKTWSRRSMIVPDMLGHTIAVHDGRKHVPVFITE-AMVGH KLGEFSPTRTFKGHV------K--DDR----RSR------RG >ACTINO_Clavibacter_michiganensis_subsp_michiganensis_NCPPB_382 Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVADFAE-ITRS------------TP-EKSLLRPLPKHGGRNNAGRITTRH-IGGGHKRQ---- YRVIDFK-RN-DK-DGVLATVAHIEYDPNRTARIALLHFI-DGSKRYIIAPNKLKQGDKIESGP-Q-AD-IKPGNNLPLR NIPTGTVIHAIELRPGGGAKMGRSAGASVRLVAK--DGPYAQLRLPSGEIRNVDARCRATIGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-HINKPSD-K-LIVRRR --------------------------------ANRTFTG-LLGTKLGMTQVWD-ENNK---------LIPVTVVQITPNV VTQVR----TPE----V--DGY--GAIQIAY-------GQ--IADK----------PSTGHFK----------------- ---AG-VTPRRHLTEVRT--------ADFAEY-----AL---GQ-EITV--G-A-FEPGTKVDVVGTSKGKGFAGVMKRH NFKG-VSASHGSHRNHRK-PGSIGAS-STPS-RVFKGMRMAGRMGGERVTVLNLVVHSVDAEKG---------------- ----------LLLVKGA-VPGARGRIVFVRTDTQLDVLD-ATGAVT-GSVDLPASLF----DV-QT-NVPLIHQVVVAQL AAARQGTHKTKGRGE--------VS-GAGRKPF---------KQKGTGRAR--------QGS---IR-AP----QM---- TGGGIVHGPT-P-RNYSQRTPKKMIAAALLGALSDRARGA----------------R-LHVIESL----SAV-------- --PSTRLIV--LERTD--E---VSLRSVRNIPTVH-V---------------LSYDQLNAYDVLVSDD----IVFTKGAF DAFVPRLKQKYRTEI----VSQLTADLGFTNVHQVPGLTKIVVNMGVG-DAARDGKIIDGAVADLTKITGQKPQVTKARK SIAQFKLREGQAIGTHVTLRGDRMWEFLDRLLSLALPRIRDFRGLSP-KQFDGNGNYTFGLNEQSMFHEID-----QDRI DRVRGMDITVVTT-----------------------ARTDDEGRALLKALGFPFMSRIG-R--LPIDVPAGVDVA-V--- -D-G--Q-HVTVKGPKGELSLTI-AQP----IRAEVQD-GQ--VLV---TR-P--DDERESR-SLHGLTRSLIANNIVGV TTGYTKGLEIVGTGY--RVAIKD-KG--VEFA--LGFSHPVYVEA-P-A-GISFTVE--GVN-KMTVVG-IDKQLVGETA ANIRKIR------KPEPY---KGKGVRYAGENVRRKAGK----------MIQQESRLKIADNTGAKEILTIRVLG-SGRR Y--AGLGDVIVATVKDAIPG-G-------NVKKGEVVKAVIVRTKKETRRPDGSYIKFDENAAVILN-SNGE-PRGTRIF GPVGRELR-DKKFMKIISLAPEVILK-V--HHLRPAAGA-KKARQRVG-RGEGSK--GKTAGRGTKGTKARYT---V--- -RVGF-E-GGQMPLHMRTPKLRG--FKNVNLEKLVTTSDLVAK-GAVRVK---------VLG--DGD-I-S-V-K-LTV- AVDKVSGSAAEKIVAAGGSV-K---QHH--PGR---TGHA-TGGTVVSFG----------EYGIQAL--TPAYVTNRQIE SARIAMTRHV------KRGGNVYINIFPDRPLTKKPAETRMGSGK---------GSVEWWVANVKP-GRVLFEL--SG-- VDEATAREALTRAIHKLPLKARI-IKSAARGRRHARLRKKV---EGTELRPRLVVTRSARHVFVQVVDD---S--RGHTV ASASTL-EADM-RTFD------G-DKTAKSRKVGELVAER--AKAAG-VESVVFDRGGNRYA--GRVAAIAEGAREGGLS L-------------------------------------------------------------MVE-SIARVRHIRVTPQK ARRVVDMIRGKQAEEALAILKFA---------------------------------PQGASEPIYKLVASAMANARVKA- DASNSFLAEQDLYIAKAFVDEGTTLKRFQPRAQGRAFRINKRTSHITVVLATMANIKKGDLVQVITGRTQAKGGDR-GKQ GKVLSVLVERN--RVV--VEGVNFITKHVR-VGQTQ--RG-SKT-GGIETVEAPIHISNVA-LVDPES-------KK--P --TRVGFRT---EQ--VEK---DGRVR---YAKKSG---KDL--MGQKVNPYGFRLG--IT-TDHVSRWFSDS----TKK GQRYSDYVAEDVRIRTML--KTSLD-----RAGVARIEIERTR-D-RVRVDIYTARPGIVIGRRGVEAERIRADLEKLIQ LNILEVKN---PEAEAQLVAQGIAEQLAGRVAFRRAMRKGLQGAQRA-GAKGVRIQVSGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFYEARTSFGRIGVKVWVYMTMTDPVADMLTRLRNANSAHHDTVSM-PHSKLKSHIADILKSEGFIAGWD VAD----A---R----VGQTLTLSLKFG---PDR-------E---RSIRGIKRVSKPGLRVYAKSAEIPQVLGGLGVAIL STSSGLLTDRQAAKKGVGGEVLAYVWMAGQKIRIRLKSYDHSVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVICVIRS PHKYKDSR-EHFEMRTHKRLIDIVDPTPKAVDSLMRLDLPADVNIEIKLRKSRRGYVTSDKMDKTIVVEVEDRVKHPLYG KVIRRTSKVKAHDEA--NTAGIGDLVLINETRPLSASKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDD-HLLRKVISANE---ASSKN----VIKTWSRRSMIIPAMLGHTIAVHDGRKHVPVFVTE-SMVGH KLGEFALTRTFRGHV------K--DDK----KGR------RR >ACTINO_Corynebacterium_diphtheriae_NCTC_13129 Concatenation of 2 sequences MAIRKYKPTTPGRRQSSVSMFEE-ITRS------------TP-EKSLVRPLPKKGGRNVHGHITVRH-KGGGHKRQ---- YRLIDFR-RN-DK-DGIPAKVAHIEYDPNRTANIALLHYV-DGEKRYIIAPKGLQQGQMIESGV-N-AD-IKVGNNLPLR NIPAGTTIHCVELKPGAGAKLARSAGASIQLLGK--AGKYAVLRMPSSEIRRVDIRCRATVGEVGNADQINIRWGKAGRM -RWK-----GVR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKKEG--RTR-NPNRYSN-N-MIVQRR --------------------------------EIK---G-ILGTKLGMTQIFD-EDNR---------VIPVTVVEAGPCV VTQIR----TVE----T--DGY--NAIQIAY-------GE--IANK----------PAAGHFK----------------- ---AG-VTPRRHVAEIRM--------DDVSGY-----EL---GQ-DVTV--E-I-FEGINFVDVTGTTKGKGYAGAMKRH GFAG-QGAAHGNQAAHRR-VGGIGAC-ATPG-RVFKGTRMAGRMGSDRVTTQNLKVQKIDADAN---------------- ----------LILIKGA-IPGVRGGIVTVKTNLKLDVLT-AEGKTD-GQVELPAEIF----DR-EA-SVALLHQVVNAQL AAKRQGTHSAKTRAE--------VS-GGGRKPF---------RQKGTGRAR--------QGS---IR-AP----HF---- TGGGISHGPK-P-RDYSQRTPKKMIKAALFGALTDRARHE----------------R-IHVISEL--VAGQT-------- --PSTKLLV--VGRED--V---TAQKSARNLPGVH-I---------------LFADQLNTYDVLYSDD----VVFSVEAL NTFIPRLKTRYREEI----RTKLNDEFSYENVMQIPGVVKVVVNMGVG-DAARDSKLINGALEDLTLITGQKPELRRAKK SIANFKLREGMPIGARVTLRGDRMWEFLDRLLTVALPRIRDFRGLSD-QQFDGHGNYTFGLSEQTMFYEID-----VDKI DRPRGMDITVVTT-----------------------ATNNEEGRALLRELGFPFMSRVG-K--APIAIPSGVDVK-I--- -D-G--Q-HVEVKGPKGTLDLTI-PEP----IVASIED-GQ--ISV---VR-P--DDHRKNR-SLHGLSRSLVNNMVVGV TEGYTIKMEIFGVGY--RVALKG-KN--LEFS--LGYSHPVLIEA-P-E-GITFAVD--G-NTKLSVSG-IDKQKVGQIA AIIRRLR------KDDPY---KGKGIRYEGEQIRRKVGK----------MIQQESRLRVADNTGAREILCIRVLG-STRR F--AGIGDVIVATVKEATPG-G-------NVKAGEVVKAVIVRAKKETRRPDGSYIKFDENAAVLIK-NDNE-PRGTRIF GPVARELR-DKKFMKIVSLAPEVIIK-L--HDLRPAKGA-NKPKTRVG-RGEASK--GKTAGRGTKGTKARKQ---V--- -SAAF-E-GGQMPLHMRLPKLKG--FKNVNVSDLIAVADIVAK-GLVRVK---------VLG--NGE-I-S-V-K-LNV- TATKFSKSAVEKIEAAGGSV-R---QHR--PHR---SGVS-KGGNRITFG----------DYGIQAL--EPAYITNRQIE SARIAINRHV------KRGGKVWINIFPDRPLTQKPLGVRMGSGK---------GPVEKWVANVKP-GRILFEM--SF-- PNEEVALEALRRAGQKLPCKVRI-VRRIARARRHDRIRKNL---RGTAETPRLVVHRSSRHMHVQVIDD---I--AGRTL AAASTL-EAEV-RA------LEG-DKKAKGAKVGQLIAER--AQAAG-ITAIVFDRGGYKYH--GRIAALADAAREGGLK F-------------------------------------------------------------ITS-ARATARFVRVSPMK ARRVIDLVRGKSVEEALAILKYA---------------------------------PQAASEPVAKVVASAAAN----A- ENNF-GLDRRSLVVSEAFADEGPTMRRFSPRAQGRAFQIRKRTSHITIVVES-MKIHKGDMVLVISGP------DK-GAK GKVIQAFPKTE--KVL--VEGVNRIKKHVA-NSAPE--RG-AES-GGIVTQEAPIHVSNVM-VLDSD--------GN--P --TRVGYRF---DE--------NGKVR---ISRRNG---KDI--MGQKIHPHGLRLG--IT-SDWKSHWYA------D-K N--YAEYLAEDIRVREYL--VKTLD-----RAGIADVVIERTR-E-RVRVDIHTARPGIVIGRRGSEADRLRTSLEKLVA LNILEVKN---IDANAQLVAQSIAEQLTNRVAFRRAMRKAIQGAMRQPQVKGIKVVCSGRLGGAEMSRTERYHEGRVPL- -HTLRAEIDYGTYEAHTTFGRIGVKVWIYMTMTDPIADMLSRVRNANNAHHDAVSM-PSSKLKANIAEILKSEGYIADYK VED----A---K----VGKTLTLDLKYG---PNR-------Q---RSIEGVRRVSKPGLRVYAKSTNLPQVLGGLGVAII STSHGLLTDRQATEKGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASAKKIVETVTRTGARVVGPVPLPTEKNVYAVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRTGYVVSDKMQKTIVVELEDRKSHAKYG KTIRTNSKVKAHDEK--EIAGIGDLVRIEETRPLSKDKHFRLVEIVEKA------------------------------- -MPRSL-KKGPFVDE-HLLNKVDAQNE---KGTKQ----VIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFVDD-SMVGH KLGEFAPTKTFKGHI------K--DDK----KGR------R- >ACTINO_Corynebacterium_efficiens_YS-314 Concatenation of 2 sequences MAIRKYKPTTPGRRASSVSMFSE-ITRS------------TP-EKSLLRPLSKTGGRNSHGHITTRH-RGGGHKRR---- YRVIDFR-RN-DK-DGVLAKVAHIEYDPNRTANIALLHYF-DGEKRYIIAPKGLTQGTVVESGA-N-AD-IKVGNNLPLR NIPTGTTIHNVELKPGAGAKLARSAGSSVQLLGK--EGPYAILRMPSTEIRRVDIRCRATVGEVGNADQINIRWGKAGRM -RWK-----GWR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-RPKRYSD-D-MIVRRR --------------------------------EIK---G-ILGTKLGMTQIFD-EENR---------VIPVTVVEAGPCV VSQIR----TVE----T--DGY--NAIQIAY-------GE--IVNQ----------PLTGHFK----------------- ---AG-VTPRRHVTEIRM--------DDVSGY-----EV---GQ-DVTV--E-I-FNDVKFVDVTGTSKGKGYAGAMKRH GFAG-QGAGHGNQAAHRR-VGGIGAA-ATPG-RIFKGKRMAGRMGNDRVTTQNLKVQKIDADAN---------------- ----------LILIKGA-IPGNRGGIVTVKTNLTLDVQT-AEGTTN-GSVDLPAEIF----DR-EV-SVALLHQVVNAQL AAARQGTHSTKTRAE--------VR-GGGRKPF---------RQKGTGRAR--------QGS---IR-AP----HF---- TGGGISHGPK-P-RDYAQRTPKKMIKAALYGALSDRARNE----------------R-IHVISEL--VPGQA-------- --PSTKLLV--IGRED--I---NAQKSANNLPGVH-I---------------LAADQLNTYDVLNSDD----IVFSVEAL HTFIPRLKSRYQDEI----RPNLQTQFEFSNVMQIPGVTKVVVNMGVG-DAARDSKMINGALEDLTAITGQKPQLRRAKK SIANFKLREGMPIGAKVTLRGDRMWEFLDRLLTVALPRIRDFRGLSD-QQFDGHGNYTFGLTEQTMFYEID-----VDKI DRPRGMDITVVTT-----------------------AVTDDEGRALLRELGFPFMSRIG-K--NPIAIPSGVEVK-I--- -D-G--R-LVDVKGPKGNLNVTL-PEP----ITASIEN-NE--ILV---TR-P--DDHRNSR-SMHGLSRSLVNNLVVGV TEGYTIKMEIFGVGY--RVALKG-KN--LEFS--LGYSHPVLIEA-P-E-GITFAVD--G-TTKLSISG-IDKQKVGQVA AVIRRLR------KDDPY---KGKGIRYEGEQIRRKVGK----------MIQQESRLKIADNTGAREILCIRVLG-STRR F--AGIGDVIVATVKEAAPG-G-------NVKSGEIVKAVIVRTKKETRRADGSYISFDENAAVIIK-NDNE-PRGTRIF GPVARELR-EKKFMKIVSLAPEVI-------------------------------------------------------- -----------MPLQMRLPKLKG--FKNVNVADLIAVADIVAA-GLVRVK---------VLG--NGD-I-S-V-K-LNV- TAHKFSGSAKEKIEAAGGSV-R---QHR--PTR---SGIS-KGGNRVTFG----------EYGIQAL--EPAYITNRQIE SARIAINRHV------KRGGKVWINIFPDRPLTQKPLGVRMGSGK---------GPVEKWVANVKP-GRILFEM--SY-- PDEAMALEALRRAGQKLPCKVRI-VRRVARARRHFRIRKTL---RGTPEAPRLVVHRSSRHMHVQIIDD---L--AGHTL AAASSI-EPEV-RA------VEG-DKKAKGAKVGQLIAER--AKAAG-IEQVVFDRAGYKYH--GRVAALADAAREGGLK F-------------------------------------------------------------ITS-ARATARFVRVSPMK ARRVIDLVRGKTVVEALSILKYA---------------------------------PQAASEPVAKVVASAAAN----A- ENNF-GLDPRTLVISEAYADEGPTMRRFQPRAQGRAFQIRKRSSHITVVVES-MKVHKGDMVLVISGP------DK-GAK GKVIAAFPKTE--KVL--VEGVNRIKKHVA-NSAPE--RG-AES-GGIVTQEAPIHVSNVM-VIDAD--------GN--P --TRVGFRV---DE--------NGKVR---VSRRSG---KDI--MGQKIHPHGLRLG--IT-SDWKSHWYA------D-Q S--YADYVAEDIKIRDFL--SKGLD-----RAGIADVVIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRRELEKLVA LNILEVKN---IDANAQLVAQSIAEQLSNRVAFRRAMRKAIQSAMRQPQVKGIKVVCSGRLGGAEMSRTERYHEGRVPL- -HTLRAEIDYGTYEAHTTFGRIGVKVWIYMTMTDPIADMLSRVRNANNAHHDTVSM-PSSKLKANIAEILKQEGYIESYT VED----A---K----VGKTLTLELKYT---GNR-------V---RSIAGLRRVSKPGLRVYAKSTNLPQVLGGLGVAII STSQGLLTDRQATEKGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYAVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRTGYVVSDKMQKTIVVELEDRKQHALYS KILRTNKKVKAHDEE--NIAGIGDLVRIEETRPLSKDKNYRLIEIIEKA------------------------------- -MPRSL-KKGPFVDE-HLLNKVDAQNE---KGTKQ----VIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFVDD-AMVGH KLGEFAPTKTFKGHV------K--DDK----KGR------R- >ACTINO_Corynebacterium_glutamicum_ATCC_13032 Concatenation of 2 sequences MAIRKYKPTTPGRRASSVSMFTE-ITRS------------TP-EKSLLRPLSKTGGRNSHGHITTRH-RGGGHKRR---- YRVIDFR-RN-DK-DGVLAKVAHIEYDPNRTANIALLHYF-DGEKRYILAPKGLTQGTVIESGA-A-AD-IKVGNNLPLR NIPTGTTIHNVELKPGAGAKLARSAGASIQLLGK--EGSYAVLRMPSSEIRRVDIRCRATVGEVGNAEQINIRWGKAGRM -RWK-----GWR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-KPKRYSD-D-MIVRRR --------------------------------EIK---G-ILGTKLGMTQIFD-EENR---------VIPVTVVEAGPCV VSQIR----TVE----T--DGY--NAIQIAY-------GE--IVNQ----------PLTGHFK----------------- ---AG-VTPRRHVTEIRM--------DDVSGY-----EV---GQ-DVTV--E-I-FNDIKFVDVTGTTKGKGYAGAMKRH GFAG-QGAGHGNQAAHRR-VGGIGAA-ATPG-RIFKGKRMAGRMGNDRVTTQNLKVQKIDADAN---------------- ----------IILIKGA-IPGNRGGIVTVKTNLKLDVQT-ADGNIN-GSVELPAEIF----DR-EV-SVALLHQVVNAQL AAARQGTHSTKTRGE--------VR-GGGRKPF---------RQKGTGRAR--------QGS---IR-AP----HF---- TGGGISHGPK-P-RDYSQRTPKKMIKAALYGALSDRARNA----------------R-IHVVSEL--VPGQT-------- --PSTKLLV--VSRED--I---NAQKSANNLPGVH-I---------------LAADQLNTYDVLKSDD----VVFSVEAL HTFIPRLKTRYQDEI----RTKLQGEFEFENVMQIPGVTKIVVNMGVG-DAARDSKLINGAIEDLTAITGQKPQLRRAKK SIANFKLREGMPIGAKVTLRGDRMWEFLDRLLTVALPRIRDFRGLSD-QQFDGHGNYTFGLTEQTMFYEID-----VDKI DRPRGMDITVVTT-----------------------AVTDDEGRSLLRELGFPFMSRIG-K--EPITIPSGVETK-I--- -D-G--Q-LVEVKGPKGTLNVNV-PEP----ISVAVED-GK--IVV---TR-P--DDHRTNR-SLHGLSRSLVNNLVVGV TEGYTIKMEIFGVGY--RVALKG-KD--LEFS--LGYSHPVLIEA-S-E-GITFAVD--G-NTKLSVSG-IDKQKVGQVA AVIRRLR------KDDPY---KGKGIRYEGEQIRRKVGK----------MIQQESRLKVADNTGAREILCIRVLG-STRR F--AGIGDVIVATVKEATPG-G-------NVKSGEIVKAVIVRTKKETRRADGSYISFDENAAVIIK-NDNE-PRGTRIF GPVARELR-EKKFMKIVSLAPEVIIK-L--HDLRPAAGS-NKAKTRVG-RGEASK--GKTAGRGTKGTKARKQ---V--- -SAAF-E-GGQMPLQMRLPKLKG--FKNVNIADLVSIADIVAA-GLVRVK---------VLG--NGD-I-S-V-K-LNV- TANKFSGSAKEKIEAAGGSA-R---QHR--PTR---SGIS-KGGNRVTFG----------EYGIQAL--EPAYITNRQIE SARIAINRHV------KRGGKVWINIFPDRPLTQKPLGVRMGSGK---------GPVEKWVANIKP-GRILFEM--SY-- PDEATALEALRRAGQKLPCKVRI-VRRVARARRHFRIRKNL---RGTPEAPRLVVHRSSRHMHVQIIDD---V--AGHTL AAASSI-EAEV-RA------TEG-DKKAKGAKVGQLIAER--AKAAG-IEQVVFDRAGYKYH--GRVAALADAAREGGLK F-------------------------------------------------------------ITS-ASATARFVRVSPMK ARRVIDLVRGKTVVEALSILKYA---------------------------------PQAASEPVAKVVASAAAN----A- ENNF-GLDPRTLVISEAYANEGPTMKRFQPRAQGRAFQIRKRSSHITVVVES-MKVHKGDMVLVISGP------DK-GAK GQVIAAFPKTE--KVL--VEGVNRIKKHVA-NSAPE--RG-AES-GGIVTQEAPIHVSNVM-VIDSD--------GN--P --TRVGYRF---DE--------NGKVR---VSRRNG---KDI--MGQKIHPHGLRLG--IT-SDWKSHWYA------D-K S--YADYVAEDIKIREFL--SKGLD-----RAGIADVVIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRRELEKLVA LNILEVKN---VDANAKLVAQSIAEQLTNRVAFRRAMRKAIQSAMRQPQVKGIKVVCSGRLGGAEMSRTERYHEGRVPL- -HTLRAEIDYGTYEAHTTFGRIGVKVWIYMTMTDPIADMLSRVRNASNAHHDTVSM-PSSKIKANIAEILKQEGYIANYT VED----A---K----VGKTLSLELKYS---NTR-------E---RSIAGLRRVSKPGLRVYAKSTNLPQVLGGLGVAII STSQGLLTDRQATEKGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYAVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRTGYVVSDKMQKTIVVEVEDRKQHALYG KILRSAKKVKAHDEE--QIAGIGDLVRIEETRPLSKDKNYRLIEIVEKA------------------------------- -MPRSL-KKGPFVDE-HLLNKVDAQNE---KGTKQ----VIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFVDD-AMVGH KLGEFAPTKTFKGHV------K--DDK----KGR------R- >ACTINO_Corynebacterium_glutamicum_R Concatenation of 2 sequences MAIRKYKPTTPGRRASSVSMFTE-ITRS------------TP-EKSLLRPLSKTGGRNSHGHITTRH-RGGGHKRR---- YRVIDFR-RN-DK-DGVLAKVAHIEYDPNRTANIALLHYF-DGEKRYILAPKGLTQGTVIESGA-A-AD-IKVGNNLPLR NIPTGTTIHNVELKPGAGAKLARSAGASIQLLGK--EGSYAVLRMPSSEIRRVDIRCRATVGEVGNAEQINIRWGKAGRM -RWK-----GWR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-KPKRYSD-D-MIVRRR --------------------------------EIK---G-ILGTKLGMTQIFD-EENR---------VIPVTVVEAGPCV VSQIR----TVE----T--DGY--NAIQIAY-------GE--IVNQ----------PLTGHFK----------------- ---AG-VTPRRHVTEIRM--------DDVSGY-----EV---GQ-DVTV--E-I-FNDIKFVDVTGTTKGKGYAGAMKRH GFAG-QGAGHGNQAAHRR-VGGIGAA-ATPG-RIFKGKRMAGRMGNDRVTTQNLKVQKIDADAN---------------- ----------IILIKGA-IPGNRGGIVTVKTNLKLDVQT-ADGNIN-GSVELPAEIF----DR-EV-SVALLHQVVNAQL AAARQGTHSTKTRGE--------VR-GGGRKPF---------RQKGTGRAR--------QGS---IR-AP----HF---- TGGGISHGPK-P-RDYSQRTPKKMIKAALYGALSDRARNA----------------R-IHVVSEL--VPGQT-------- --PSTKLLV--VSRED--I---NAQKSANNLPGVH-I---------------LAADQLNTYDVLKSDD----VVFSVEAL HTFIPRLKTRYQDEI----RTKLQGEFEFENVMQIPGVTKIVVNMGVG-DAARDSKLINGAIEDLTAITGQKPQLRRAKK SIANFKLREGMPIGAKVTLRGDRMWEFLDRLLTVALPRIRDFRGLSD-QQFDGHGNYTFGLTEQTMFYEID-----VDKI DRPRGMDITVVTT-----------------------AVTDDEGRSLLRELGFPFMSRIG-K--EPITIPSGVETK-I--- -D-G--Q-LVEVKGPKGTLNVNV-PEP----ISVAVED-GK--IVV---TR-P--DDHRTNR-SLHGLSRSLVNNLVVGV TEGYTIKMEIFGVGY--RVALKG-KD--LEFS--LGYSHPVLIEA-S-E-GITFAVD--G-NTKLSVSG-IDKQKVGQVA AVIRRLR------KDDPY---KGKGIRYEGEQIRRKVGK----------MIQQESRLKVADNTGAREILCIRVLG-STRR F--AGIGDVIVATVKEATPG-G-------NVKSGEIVKAVIVRTKKETRRADGSYISFDENAAVIIK-NDNE-PRGTRIF GPVARELR-EKKFMKIVSLAPEVIIK-L--HDLRPAAGS-NKAKTRVG-RGEASK--GKTAGRGTKGTKARKQ---V--- -SAAF-E-GGQMPLQMRLPKLKG--FKNVNIADLVSIADIVAA-GLVRVK---------VLG--NGD-I-S-V-K-LNV- TANKFSGSAKEKIEAAGGSA-R---QHR--PTR---SGIS-KGGNRVTFG----------EYGIQAL--EPAYITNRQIE SARIAINRHV------KRGGKVWINIFPDRPLTQKPLGVRMGSGK---------GPVEKWVANIKP-GRILFEM--SY-- PDEATALEALRRAGQKLPCKVRI-VRRVARARRHFRIRKNL---RGTPEAPRLVVHRSSRHMHVQIIDD---V--AGHTL AAASSI-EAEV-RA------TEG-DKKAKGAKVGQLIAER--AKAAG-IEQVVFDRAGYKYH--GRVAALADAAREGGLK F-------------------------------------------------------------ITS-ASATARFVRVSPMK ARRVIDLVRGKTVVEALSILKYA---------------------------------PQAASEPVAKVVASAAAN----A- ENNF-GLDPRTLVISEAYANEGPTMKRFQPRAQGRAFQIRKRSSHITVVVES-MKVHKGDMVLVISGP------DK-GAK GQVIAAFPKTE--KVL--VEGVNRIKKHVA-NSAPE--RG-AES-GGIVTQEAPIHVSNVM-VIDSD--------GN--P --TRVGYRF---DE--------NGKVR---VSRRNG---KDI--MGQKIHPHGLRLG--IT-SDWKSHWYA------D-K S--YADYVAEDIKIREFL--SKGLD-----RAGIADVVIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRRELEKLVA LNILEVKN---VDANAKLVAQSIAEQLTNRVAFRRAMRKAIQSAMRQPQVKGIKVVCSGRLGGAEMSRTERYHEGRVPL- -HTLRAEIDYGTYEAHTTFGRIGVKVWIYMTMTDPIADMLSRVRNASNAHHDTVSM-PSSKIKANIAEILKQEGYIANYT VED----A---K----VGKTLSLELKYS---NTR-------E---RSIAGLRRVSKPGLRVYAKSTNLPQVLGGLGVAII STSQGLLTDRQATEKGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYAVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRTGYVVSDKMQKTIVVEVEDRKQHALYG KILRSAKKVKAHDEE--QIAGIGDLVRIEETRPLSKDKNYRLIEIVEKA------------------------------- -MPRSL-KKGPFVDE-HLLNKVDAQNE---KGTKQ----VIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFVDD-AMVGH KLGEFAPTKTFKGHV------K--DDK----KGR------R- >ACTINO_Corynebacterium_jeikeium_K411 Concatenation of 2 sequences MAIRKYKPTTPGRRQSSVSEFAE-ITRS------------TP-EKSLLRPLSKTGGRNVHGHITTRH-KGGGHKRR---- YRVIDFR-RN-DK-DGVLAKVAHIEYDPNRTANIALLHYR-DGEKRYIIAPRGLQQGALLESGP-N-AD-IKVGNNLPLR NIPTGTTIHAVELKPGGGAKMARSAGASIQLLGK--EGKYAVLRMPSTEIRRVDIRCRATIGEVGNADQINIRWGKAGRM -RWK-----GVR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPEG--RTR-KPNRPSD-R-MIVRRR --------------------------------EIK---G-ILGKKLGMTQIFD-EENR---------VVPVTVVEAGPCV VTQVR----SKE----T--DGY--EAVQIAF-------GE--IVNK----------PAAGHFK----------------- ---AG-VTPRRHVAEIRV--------ADASSY-----EV---GQ-DVTV--D-I-FNDVKFVDVTGTTKGKGYAGGMKRH GFAG-QGAAHGNQAAHRR-VGSIGQA-ATPG-RVFKGKRMAGRMGNDRVTQQNLKLAKVDAESN---------------- ----------LLLIKGA-VPGVNGGLVVVKSNLKLDVHT-ADGKTN-GTVELPASIF----DA-EA-SVALMHQVVTAQL AAKRQGTHATKTRGM--------VS-GGGRKPF---------RQKGTGRAR--------QGS---IR-AP----HF---- TGGGTVHGPQ-P-RDYSQRTPKKMKAAALRGALTDRVRHD----------------R-IHVVEEL--VPGQT-------- --PSTKLVV--LTRED--V---TAWKSVNNLPQVH-T---------------LVNDQLNTYDVLNADD----VVFSVEAL NAFIPRLKTRYREEI----REKLNGEFSYENVMQIPGVTKVVVNMGVG-DAARDSKLINGAIEDLTKITGQKPQIRTAKK AIANFKLREGMPIGARVTLRGDRMWEFLDRLLTVALPRIRDFRGLND-KQFDGHGNYTFGLSEQSMFYEID-----VDKI DRPRGMNITVVTT-----------------------ATNDDEGRALLRELGFPFMSRVG-K--APVAVPSGVTIN-I--- -N-G--Q-SVEVKGPKGTLSQDI-PAP----ITVAQEG-EE--LVV---SR-P--DDHRKNR-SLHGLSRSLVFNMIEGV TKGYTINMEIFGVGY--RVQLKG-KN--LEFA--LGYSHPVLIEA-P-E-GITFAVD--G-NTKFSIAG-IDKQQVGQIA ANIRRLR------KDDPY---KGKGIRYEGEQVRRKVGK----------MIQQESRLRVADNTGAREILVIRPLG-SVRR S--AGIGDVVVATVKEAAPG-G-------TVKAGDIVKAVIVRAKKETRRPDGSYIAFDENAAVIIKANDND-PRGTRIF GPVARELR-DKKFMKIVSLAPEVLIK-L--HDLRPAPGA-KKAKTRVG-RGEASK--GKTAGRGTKGTKARKQ---V--- -SAAF-E-GGQMPLHMRLPKLKG--FKNVNVSDLVTVADIVAA-GLARVK---------VLG--NGE-I-S-V-K-LNV- TANKFSGSAKQKIEAAGGTV-R---QHR--PHR---SGVS-KGGNRVTFG----------DYGLQAL--EPTYITNRQIE SARIAINRHM------KRGGKVWINIFPDRPLTQKPLGVRMGSGK---------GPVEKWVANVKP-GRILFEA--SY-- PNEEVALEALRRAGNKLPCKVRI-VRRTARARRHFRIRKTL---SGTPETPRLVIHRTSRHMHAQVIDD---V--AGHTL VAASTM-EADV-RA------MEG-DKKARGAKVGQLIAER--AKAAG-IEAVVFDRAGYKYH--GRVAALADAAREGGLK F-------------------------------------------------------------VTT-ARATARFVRVTPMK ARRVIDTIRGKSVEDALAILKYA---------------------------------PQAASEPVAKVVASAAAN----A- ENNF-GLDPQTLVVSEAYADEGPTMRRFRPRAQGRAFHVRKRTSHITVVVES-MKIRKGDTVLVISGP------DK-GAK GKVIEAYPQRD--KVL--VEGVNRIKKHVA-NSAPE--RG-AES-GGIVTQEAPIHVSNVM-VVDSD--------GN--P --TRIGYRF---DE--------DGKIR---VSKRNG---KDI--MGQKIHPHGLRLG--IT-SEWRSRWYA------D-K Q--YADYLAEDIKIRDFL--SEGLD-----RAGIANVVIERTH-D-RVRVDIHTARPGIVIGRRGSEADRIRGQLEKLVQ LNILEVKN---IDANAQLVAQSIAEQLTNRVAFRRAMRKAIQGAMRQPQVKGIKVVCSGRLGGAEMGRTERYHEGRVPL- -HTLRAEIDYGTYEAHTTFGRIGVKVWIYMTMTDPIADMLSRVRNASNAFHESVSM-PSSKIKANIAEILKEEGYIADYT VND----A---K----VGKTLDIELKYG---PSR-------E---RSISGLRRVSKPGLRVYAKSNELPQVLGGLGVAII STSHGLLTDREAQNKGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASAKKIVETVTRTGARVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRSGYVVSTKMNKTIVVELEDRKQHALYG KIMRRNSRVKVHDEN--ETAGVGDRVRIEETRPLSKDKHFRLTEVIEKA------------------------------- -MPRSL-KKGPFVDE-HLLAKVDAQNE---KGNKN----VIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFIDD-SMVGH KLGEFAPTKTFKGHV------K--DDK----KGR------R- >ACTINO_Cryptobacterium_curtum_12-3,_DSM_15641 Concatenation of 2 sequences MGVKQFKPTSPGRRFQTVSDFAE-ITCD------------KP-EKSLLRPLPKKAGRNNYGRITTRH-QGGGAKRR---- YRIIDFK-R--NK-DGVPAKVATIEYDPNRSARIALLHYA-DGEKRYILQPRDLKVGDTVLSGA-D-AD-IKPGNALPLS AIPVGTLIHAVELQPGRGAALARSAGTSIQLMGK--EGKYAILRMPSSEMRRVLLTCRATVGEVGNADHSNIKIGKAGRN -RWA-----GIR-P-TVRGTVMNPVDHPHGGGEGKNKT--SGRH-PVSP---WGVPTKGHRTR-NPKKASS-R-LIIRRR --------------------------------MIN---A-IYGTKLGMTQIFS-EDDE---------VVPVTVIQAAPNT ICQLK----TKE----T--DGY--EAVQLGF-------GA--IVNR----------PMGGHFK----------------- ---QG-VDPVRHLREVRV--------EDASAH-----SL---GE-KVTV--S-L-FADAKKVDVTATSKGKGFAGVMRRY NFRG-GPGGHGA-HFHRA-PGSVGMC-ATPS-RVFKGLRLPGHMGVDTVTVKNLDVVRIDEEQN---------------- ----------LILVKGA-VPGGKNAMVRVR-MANIEVKD-VSGKKV-EVRDLNAGVF----GI-EP-NVHVMHQVVRAQR ASWRQGTHDTLTRGQ--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPH-P-RSYAFRVNNKEVKLAMRSALSAKLADG----------------E-LFVVDSF----GFE-E------ --PKTKTLV--IGNED--V---NTYLAFRNLPNVE-V---------------IPVMAGNTYDFVNNKA----LIFTAEAL SRIEPRLKERYQSEI----VPKLASDLSLTNVNQVPRLEKIVVNMGVG-AAAGDSKLLDAAISDMRVITGQQPMITRAKK SIAGFHVREGQAIGCKVTLRGDRMWEFLDRLLATALPRVRDFRGISP-KSFDSHGNYTLGITEQLIFPEID-----YDKI DRTRGMDITFVTT-----------------------AEDDATAKALFDALGFPFMSRIG-K--QPVVVPSGVDVK-I--- -D-G--H-TVTVKGKQGELTRSF--NP-L--MSISQEG-DS--IIV---SR-P--DDSREAK-SLHGLTRTLIHNMVIGA SEGFSKKLELVGVGY--RAALKG-KN--LEMQ--LGFSHPVVIEP-P-A-GIVFEVP--S-PTEILVKG-PSKEAVGQIA ANVRAWR------KPEPY---KGKGIRYEGEHVRRKLGK----------MIQMQTMLAVADNSGARKVQCIKVLG-SKRR Y--AGLGDVIICSVKEAIPN-G-------QVKKGEVVRCVVVRQKKEVRRSDGSYIRFDQNACVLID-ASGA-PRGTRIF GPVARELR-DKKYMKIVSLAPETLME-L--KDLTPAAGS-RKQRTRVG-RGHAAGK-GKTAGRGLNGQKSRSGGG-K--- -RPGF-E-GGQTPLYMRLPKLPG--FRNVNVSRLIDNAALVAA-GIIKVK---------VLG--DGE-I-T-K-A-LTV- KVDKVSASAAKKIEAAGGKV-K---VQR--GSM---KGRA-KGGTRLNHG----------EWGIQAL--EAHWITNRQIE AARVAITRQM------KRGGHVWITIFPDKPITSKPAETRMGSGK---------GNPEGWVAVVKP-GRIMFEI--GG-- VDEATAKEACRLAINKLPIKCKI-VKQASLRRRHTRVRGKV---FGTSARPRLCVTRSNSNVYVQIVDD---V--DRKTL CAVSTL-GPDF-KATG----KSG-ANVEGAGVLGEIIGKK--AIEAG-ITEVVFDRGGHLYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-AKAVARYVRVSPRK ARVVVDQIRGKDIVRAREVLAFT---------------------------------TRAIAEDVEKVMNSAVAN----A- EHNH-QANPAQLYVKAAYVDEGPTLKRIRPRAKGSAARIRKRTSHITVIVSTTMNIKKGDKVKVLAGK------DK-GVE STVIRSLPQRN--RVV--VEKVGMVTKAQR----PT--QA-NPQ-GGLSHIEAPIHVSNVA-LVCPKC-------GK--A --TRFSIKR----E--------DGKIR---VCKKCG---ADI--MGQKVSPTGFRIG--VI-ENWRSRWYA------D-K D--YAKTLENDLAIRRFL--DGYLT-----RAAVSKVEIERAG-D-KIKVVITTARPGVVIGKKGAEIDTLRKKLSQVIS VEVIEIKR---PELDANLIAQSVAEQLEGRVAFRRAMRKAVQSARKS-GAQGIRIQCAGRLGGAEMSRREWYREGRVPL- -HTLRAKIDYGFTTANTQMGAIGVQVWVYMSMNDPIADMLTRVRNAHSAGKDTVSM-PSSKKLVEIARIMREEGYIAGYE IEP----A---K----PRDILEITLKYG---EKK-------E---RTIRGIKRISKPGLRIYAGKDELPRVLGGLGTAVI STSAGVMADRDARKKGIGGEVIAYIWMANQKIRIRLKGYDHEIVDQSTKLIVDTAQKTGAKVSGPIPLPTERNLYCVVKG PHVDKDSR-EQFEMRTHKRLIDILEPTPNTVDSLMRLDLPAGVDIEIKLRKVRQGLVVSISGDKTCVVEVKERKPHRVYG KMMTTTKKFHTHDEN--NEAGLGDTVRIMETRPLSKMKHWRLIEIVEKA------------------------------- -MSRSL-KKGPFVEP-RLLSRIDAMNE---AGTKD----VVKTWSRSSTIFPEMVGHTIAVHDGRKHVPVYITE-SMVGH KLGEFAPTRTFRGHA----------KK--------------- >ACTINO_Eggerthella_lenta_VPI_0255,_DSM_2243 Concatenation of 2 sequences MGVKQYKPTSPGRRFQTVSDFAE-ITTS------------TP-EKSLLAPLSNKAGRNNNGRITTRH-QGGGNKRR---- YRIIDFK-R--NK-DGVPAKVATIEYDPNRSARIALLHYV-DGEKRYILHPKGLRVGDTVMSGV-E-AD-IKPGNALPLA NIPVGTLIHAVELQPGKGAAIARSAGTSIQLMGK--EGDYAILRMPSSEMRRVLITCRATVGEVGNAEHSNIKIGKAGCN -RWK-----GIR-P-SVRGTVMNPVDHPHGGGEGKNKS--AGRH-PVTP---WGVPTKGHRTR-NPKKASS-R-LIIRRR --------------------------------MIN---A-IYGKKIGMTQIFN-EDDR---------VVPVTVIQAEPNT ICQVK----TKD----S--DGY--EAVQLGF-------GA--IVNK----------PMAGHFK----------------- ---QG-TAPTRYLREVRV--------ENAGEY-----KV---GD-QQTV--A-A-FAETKKVDVTGTSKGKGFAGVMKRY GFRG-GPGGHGA-HFHRA-PGSVGQC-ATPS-RVFKGLKLPGHMGVDTVTVKNLEVVRIDEEQN---------------- ----------LILVKGA-IPGGKNGVVRVR-MTTIEIKD-ASGKKA-GTADLAASVF----GI-EP-NVPVMHQVVRAQR ASWRQGTHDTKTRGQ--------VR-GGGKKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- AGGGTVFGPH-P-RSYAFRVNNKEVKLAMRSALSAKLADG----------------E-LFVVDAF----NFE-K------ --PSTKLVI---DDED--V---NTYLSFRNIPTVN-I---------------LPVSAANTYELIDNKA----LVFTADAL KRIEPRLKEKYTNEI----VAKLEKDLALDNVNKVPRLEKIVVNMGVG-AAAADHKLLDAAMGDLRIITGQQPCVTRAKK SIAGFHVREGQPIGCKVTLRGDRMWEFLDRLLATALPRVRDFRGISP-TSFDGRGNYTMGVTEQLIFSEID-----YDKI DRTRGMDITFVTT-----------------------APDDDSAFALLDALGFPFMSRIG-K--LPVTVPAGVDVT-I--- -D-G--T-TVTAKGAKGELTRTF--PE-I--MTIKREG-DD--IIV---ER-P--NDSREAK-AYHGLVRTLIANMVEGV SAGFSKKLQLVGVGY--RAALKG-KD--LEMQ--LGFSHPVLVEA-P-E-NITFEVP--S-QTEIIVSG-PSKEQVGQVA ANIRKWR------KPEPY---KGKGIRYEGEHVRRKVGK----------MIQMQTMLAVADNSGARKVQCIKVLG-SKRR Y--AGLGDVIICSVKEAAPN-T-------NVKKGDVVRCVVVRVKKEVRRVDGSYIKFDQNAAVLID-TNGA-PRGTRIF GPVARELR-DKKYMKIVSLAPETLME-L--KDLKPAEGS-RKPRKRVG-RGPASGT-GKTSGRGMNGQKSRAGGG-K--- -GAGF-E-GGQTPLARRLPKLPG--FKNVNVKRLVNGESLKAK-GIIKVK---------VLG--DGE-I-T-K-A-LTV- QVDKVSASAKAKIEAAGGKV-K---VQR--GSM---KGKA-KGGTRLNHG----------EYGIQAL--EAAWITNRQIE AARIAMTRYM------KRGGKVWITIFPDKPITKKPAETRMGSGK---------GNPEAWVAVVKP-GRIMFEI--GG-- VDEAVAKEALRLAINKLPIKCKI-VKQAALARRHRRVRGKI---AGTAARPRVCVTRSNSNMYVQVIDD---V--AGKTI CGVSTL-GPDF-KATG----KSG-ATVEGAAALGAIVGKK--AQESG-VTEVVFDRGGNLYH--GRIKALADAAREAGLK F--------------------------------------------------------------ME-AKAIARYVRVSPRK ARIVIDLIRGKSVPAAREILQFS---------------------------------DRAIAEVVAKTLNSAVAN----A- ENQH-HVRPETLIVKAAFADEGPTLKRIRPRAKGSASRIRKRTSHITIIVAPSMNIKKGDKVKVLAGK------DK-GKE GTILRSLPQKQ--RVV--VEKVNIVKKALR----PT--QQ-NPQ-GGISSVEAPIHVSNVM-LVCPSC-------KQ--P --TRVSNKR---DE--------NGKVR---VCKKCG---KDI--MGQKVSPTGFRLG--IT-EEWRSRWYA------D-K D--YAKNLANDLAIRKFL--DKQLA-----RAAVSKIEIERAG-D-KIKIIVTTARPGVVIGKKGAEIDSLRKKLEKVVS IEVVEVKR---PELDAALIAQSVAEQLEGRVAFRRAMRKAVQSARKS-GAKGIRIQCSGRLGGAEMSRREWYREGRVPL- -HTLRAKIDYGFATAATTMGSIGVQVWVYMTMTDPIADMLTRVRNANSAGKPTVSM-PSSKKLVEIARIMQEEGYVQGYD VIE----G---E----PRATLEITLKYG---DKK-------A---KTIRGIKRISKPGLRIYAGKDELPRVLGGLGTAIV STSNGVMTDRDARKKGVGGEVIAYIWMANQKIRIRLKGYDHEIVDQSTKLIVDTAQKTGAKVSGPIPLPTERNLYCVVKG PHVDKDSR-EQFEMRTHKRLIDILEPTPNTVDSLMRLDLPAGVDIEIKLRKVRQGVVVSAVNDKTCVVQVKERKPHPVYG KMMTTTKKFHAHDEN--NEAGLGDTVQIMETRPLSKMKRWRLVKIVEKA------------------------------- -MSRSL-KKGPFVEP-RLLDRIEKMNA---AGEKN----VVKTWSRSSTIFPEMVGHTIAVHDGRKHVPVYVTE-SMVGH KLGEFAPTRTFKGHS------A---DK---GKKR-------- >ACTINO_Frankia_alni_ACN14a Concatenation of 2 sequences MGIRRYKPTTPGRRGASVADFVE-ITRD------------HP-EKSLVRPLHSKGGRNVHGRITTRH-QGGGHKRA---- YRIIDFR-R--DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPVKLKQGDQVSSGV-G-AD-IKPGNALPLR NIPTGTVVHAIELRPGGGAKIARSAGASVQLVAK--DGPYAQLRMPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GRR-P-TVRGVAMNPVDHPHGGGEGKT----SGGRHPVNP---KGRP--EGRTR-ANHKSSD-A-LIVRRR --------------------------------LIRNYRG-LLGTKLGMTQVWD-ANNR---------VVPVTVIKAGPNV VTQVK----TPD----S--DGY--SAVQLGY-------GE--IINK----------PARGHFT----------------- ---SG-VTPRRHLVELRT--------ADAGNY-----RP---GQ-ELTG--E-V-FAEGTVVDVTGTSKGKGFAGVMKRH GFKG-LGAGHGVERKHRS-PGSVGGC-ATPG-RVFKGLRMAGRMGHARTTTPGLTIHAVDTERG---------------- ----------FLLVKGA-IPGPDGGLVFVRTTRTVSVHA-PNGGDG-GSAELPGGVF----DV-PL-NVPLIHQVVVAQL AAARQGTHATKTRGE--------VR-GGGRKPY---------RQKGTGRAR--------QGS---LR-AP----QF---- TGGGVVHGPT-P-RSYDQRTPKKMKAAALRGALSDRARNN----------------R-VHVVSSL--VSGEA-------- --PSTKLVV--ASRTD--E---LTWKSLRNVAAVH-L---------------LDPGQLNTYDVLVSDD----VVFTEEAL AAFLPRLKQRYREEI----AATLREEFSYRNVMQIPGVVKVVVNMGVG-DAARDAKLIDGAVRDLAAITGQKPAVRRAKK SIAQFKLREGMPIGAKVTLRGDRMWEFLDRLVSIALPRIRDFRGLSP-KQFDGAGNYTFGVTEQSIFHEID-----IDRI DRVRGMDITVVTT-----------------------ATTDDEGRALLRALGFPFMSRIG-R--LPIPVPSGVDIT-V--- -E-G--A-TVTVKGPKGTLSHVV-VEP----IAVNREE-GQ--LVV---TR-P--DDERRSR-SLHGLTRTLVSNMVTGV TAGYSKTLEIVGVGY--RVQAKG-SD--LEFA--LGYSHPVPVKA-P-E-GIRFEVQ--T-PTRFVVHG-IDKQLVGEVS AKIRGLR------KPDPY---KGKGVRYQGEVVRRKVGK----------MIQQESRLRVADNTGAREILCIRVLG-SGRR Y--AGIGDIIVGTVKDALPG-A-------GVKRGDVVKAVVVRTTKERRRPDGSYIRFDENAAVLIR-DGGD-PRGTRIF GPVGRELR-DKKFMKIISLAPEVLLK-V--HHLRPAPGA-HRSRIRVG-RGEGSK--GKTAGRGTKGSKARKQ---V--- -PARF-E-GGQMPLHMRLPKLKG--FSNVNLSTLVAKADLVAK-GAVRVK---------VLG--NGD-I-D-V-A-LHV- SADAFSASAREKIAAAGGSV-K---QHH--PGR---TGAA-KGGTRVTFG----------EYGIQAL--ESAYVTNRQIE SARIAMTRHI------RRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SG-- VAEPVAREAMRRAIHKLPMKCRF-V---------------M---AGTQSRPRLVVTRSSRHIYAQVIDD---V--AGHTL ASASTL-DVTL-RG------GEG-DKSSQARKVGELVAQR--AKAAG-IDAVVFDRGGRTYA--GRIAALADAARESGLD F-------------------------------------------------------------LPG-AKASARYVRVSPTK ARRVVDLVRGRSVSEALDILRFA---------------------------------PQAASDDVYKVVASAAAN----A- ENNH-SLDPATLWVGEVYVDEGPTLKRIRPRAQGRAYRIRKRTSHITVVVESTLKIKKGDTVQIITGK------DR-GLK GKVIRAYPEQN--KVL--VEGANRITRHTR--VQQS-ARG-SQS-GGIVTQEAPIHVSNVM-IVDPSD-------GR--P --TRIGYRI---NE--------DGKVR---ISRRTG---AEL--MGQKVNPHGFRLG--IT-SEFTSRWYA------D-K Q--YKAYVGEDVKIRKMM--SRGME-----RAGISRVDIERTQ-G-RLRVDIHTARPGIVIGRRGAEADRIRGDLEKLVQ LNILEVKN---PEVDAQLVAQGVAEQLSSRVSFRRAMRKAMQTAMKG-GAKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGFYEARTNFGRIGVKVWIY---------MLTRVRNASRAYHDSVVM-PHSKIKTHIAEILQQEGYISSWH VDDATLAG---G----VGHTLVIDLKYG---PNR-------E---RSIAGIKRISKPGLRVYAKATNLPKVLGGLGVAII STSSGLLTDKQAGKRGVGGEVLAYVWMAAQKIRIRLKAYDHEVIDSSARKIVETVTRTGAQVAGPVPLPTEKNIYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVVSDKMTKTVVVAVEDRVQHPLYG KTIRRTKKVKAHDEN--GTTGVGDRVLLMETRPLSATKRWRVVQVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNS---KGTKH----VIKTWSRRSTVIPDMLGHTIAVHDGRKHVPVFITE-GMVGH KLGEFAPTRTFRGHV------K--EDR----RSR------RG >ACTINO_Frankia_sp_CcI3 Concatenation of 2 sequences MGIRRYKPTTPGRRGASVADFVE-ITRD------------HP-EKSLVRPLHSKGGRNVHGRITTRH-QGGGHKRA---- YRVIDFR-R--DK-DGVPAKVAHIEYDPNRTARIALLHYL-DGEKRYILAPVKLRQGDTVSSGV-G-AD-IKPGNALPLR NIPTGTVVHAIELRPGGGAKIARSAGTSVQLVAK--DGPYAQLRMPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GRR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---KGRPEG--RTR-ATRKSSD-A-LIVRRR --------------------------------NYR---G-LLGTKLGMTQVWD-ANNR---------VVPVTVIKAGPNV VTQVK----TPD----S--DGY--SAVQLGY-------GE--VINK----------PARGHFT----------------- ---SG-VTPRRHLVELRT--------ADAGNY-----RP---GQ-ELTG--E-V-FSAGTVVDVTGTSKGKGFAGVMKRH GFKG-LGAGHGVERKHRS-PGSVGGC-ATPG-RVFKGLRMAGRMGHVRTTTSGLTIHAVDTERG---------------- ----------YLLVRGA-VPGPDGGLVLVRTARTVAVHA-PNGGEG-GSVELPGGVF----DV-PL-NIPLIHQVVVAQL AAARQGTHDTKTRGE--------VR-GGGRKPY---------RQKGTGRAR--------QGS---LR-AP----QF---- TGGGTVHGPT-P-RRYDQRTPKKMKAAALRGALSDRARNN----------------R-VHVVSSL--VSGET-------- --PSTKLVV--ASRSD--E---LTWKSLRNVAAVH-L---------------LDPGQLNTYDVLVSDD----VVFIEDAL AAFLPRLKQRYRDEI----APALREQFSYRNVMQIPGVVKVVVNMGVG-DAARDAKLIDGAVRDLAAITGQKPAVRRAKK SIAQFKLREGMPIGAKVTLRGDRMWEFLDRLVTIALPRIRDFRGLSP-KQFDGAGNYTFGVTEQSIFHEID-----IDRI DRVRGMDITVVTT-----------------------ATTDDEGRALLRALGFPFMSRIG-R--LPIPVPSGVDIT-V--- -E-G--A-TITVKGPKGTLSHVV-AEP----IVVNTED-GR--LLV---TR-P--DDERRSR-SLHGLTRTLVSNMVTGV TAGYSKTLEIVGVGY--RVQAKG-SD--LEFA--LGYSHPVPVKA-P-E-GIRFEVQ--T-PTRFVVHG-IDKQLVGEVS AKIRGLR------KPDPY---KGKGVRYQGEVVRRKVGK----------MIQQESRLRVADNTGAREILCIRVLG-SGRR Y--AGIGDIIVGTVKDALPG-A-------GVKRGDVVKAVVVRTTKERRRPDGSYIRFDENAAVLIR-DGGD-PRGTRIF GPVGRELR-DKKFMKIISLAPEVLLK-V--HHLRPAPGA-HKSKIRVG-RGEGSK--GKTAGRGTKGSKARKQ---V--- -PARF-E-GGQMPLHMRLPKLKG--FRNVNVATLVTKADLAAR-GAVRVK---------VLG--NGD-I-N-V-A-LHV- SADAFSASAKEKIAAAGGSV-K---QHH--PGR---TGAA-KGGTRVTFG----------EYGIQAL--ESAYVTNRQIE SARIAMTRHI------RRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SG-- VAEPVAREAMRRAIHKLPMKCRF-VRRTAKLRRHVRVRKKV---AGTPSRPRLVVTRSSRHIYAQVIDD---V--AGHTL ASASTL-DVSL-RG------GEG-DKTEQARKVGALVAER--AKAAG-IAAVVFDRGGRTYS--GRIAALADAARGNGLD F-------------------------------------------------------------LPG-AKASARYVRVSPTK ARRVVDLVRGRSVGEALDILRFA---------------------------------PQAASEDVYKVVASAAAN----A- ENNH-SLDPATLWVGEVYVDEGPTLKRIRPRAQGRAYRIRKRTSHITVVVESTLKIKKGDTVQIITGK------DR-GLK GKVIRAYPEQN--KVL--VEGANRITRHTR--VQQG-TRG-SQS-GGIITQEAPIHVSNVM-IVDPSD-------GK--P --TRIGYRI---ND--------DGKVR---VSRRTG---TEL--MGQKVNPHGFRLG--IT-SEFTSRWYA------D-K Q--YKAYVGEDVKIRKMM--SRGME-----RAGISRVDIERTQ-G-RLRVDIHTARPGIVIGRRGAEADRIRGDLEKLVQ LNILEVKN---PEVDAQLVAQGVAEQLSSRVSFRRAMRKAMQTAMKG-GAKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGFYEARTNFGRIGVKVWIYMTMTDPIADMLTRVRNASRAYHDRVVM-PHSKIKTHIAEILQQEGYISGWH VEDATSAG---G----VGHTLVIDLKYG---PNR-------E---RSIAGIKRISKPGLRVYAKATNLPKVLGGLGVAII STSSGLLTDKQAGKRGVGGEVLAYIWMAAQKIRIRLKAYDHEVIDSSARKIVETVTRTGAQVAGPVPLPTEKNIYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVVSDKMTKTVVVAVEDRVQHPLYG KTIRRTKKVKAHDES--GTTGVGDRVLLMETRPLSATKRWRIVQVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDLQNS---KGTKH----VIKTWSRRSTVIPDMLGHTIAVHDGRKHVPVFITE-GMVGH KLGEFAPTRTFRGHV------K--EDR----RSR------RG >ACTINO_Frankia_sp_EAN1pec Concatenation of 2 sequences MGIRRYKPTTPGRRGSSVADFVE-ITRD------------HP-EKSLVRPLHSKGGRNVHGRITTRH-QGGGHKRA---- YRIIDFR-R--DK-DGVPAKVAHIEYDPNRTARIALLHYV-DGEKRYILAPVKLHQGDMVSSGV-G-AD-IKPGNALPLR NIPTGTVVHAIELRPGGGAKIARSAGASVQLVAK--DGPYAQLRMPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GRR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---KGRPEG--RTR-RTKKSSD-A-LIVRRR --------------------------------NYR---G-LLGTKLGMTQVWD-ANNR---------VVPVTVIQAGPNV VTQVK----TPD----S--DGY--SAVQLGY-------GE--IINK----------PMRGHFT----------------- ---SG-ATPRRHLVELRT--------ADAGNY-----RP---GQ-QLTG--E-V-FDAGQVVDVTGTSKGKGFAGVMKRH GFKG-LGAGHGVERKHRS-PGSVGGC-ATPG-RVFKGLRMAGRMGHDRVTVAGLTIHAVDTERG---------------- ----------FLLIKGA-IPGPDGGLVFVRVDRTVPVHA-PAGGDA-GSVELPGAVF----DV-PV-NVPLIHQVVVAQL AAARQGTHSTKTRGE--------VR-GGGRKPY---------RQKGTGRAR--------QGS---LR-AP----QF---- TGGGIVHGPT-P-RNYDQRTPKKMKAAALRGALSDRARNN----------------R-LHVVSSL--VAGDT-------- --PSTKLVV--ALRSD--E---LTWLSLRNVAEVH-L---------------LDPGQLNTYDVLVSDD----VVFTEGAL AAYLPRLKQRYREEI----APALREEFSYGNVMQIPGVVKVVVNMGVG-DAARDAKLIDGATRDLAAITGQKPAVRRAKK SIAQFKLREGQPIGAKVTLRGDRMWEFLDRLVTIALPRIRDFRGLSP-KQFDGAGNYTFGVIEQSIFHEID-----IDRI DRVRGMDITVVTT-----------------------ATNDDEGRALLRALGFPFMSRIG-R--QPISVPTGVEIS-L--- -D-G--P-KVTIKGPKGSLSHTV-AEP----IEVVRED-GQ--LIV---NR-P--NDERRSR-ALHGLTRTLVSNMVVGV TAGYSKTLEIVGVGY--RVQARG-SD--LEFA--LGYSHPVPVKA-P-D-GIRFEVQ--T-PTRFVVHG-IDKQQVGEVA AKIRGLR------KPDPY---KGKGVRYQGEVVRRKVGK----------MIQQESRLRVADNTGAREILCIRVLG-SGRR Y--AGIGDIIVGTVKDALPG-A-------GVKRGDVVKAVVVRTKKERRRPDGSYIRFDENAAVLIR-DGGD-PRGTRIF GPVGRELR-DKRFMKIISLAPEVLLK-V--HHLRPAPGA-HKKKQRVG-RGEGSK--GKTAGRGTKGSKARKQ---V--- -PARF-E-GGQMPLHMRVPKLKG--FRNVNVATLIGVDELVAA-GAVRVK---------VLG--DGE-I-G-V-A-VQV- TAHAFSGSAKQKIEAAGGSV-K---QHH--PKR---TGAA-KGGTRIAFG----------EYAIQSL--ESAYVTNRQIE SARIAMTRHI------RRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRIMFEL--SG-- VAEPVAREAMRRAIHKLPMKCRF-VRRTAKLRRHVRVRKKV---SGTPIRPRLVVTRSSRHIYAQVIDD---V--AGHTL ASASTL-EDGL-RA------SDG-DKSAKAREVGRLVAER--ARAAG-IDAVVFDRGGRTYH--GRIAALADAAREGGLN F-------------------------------------------------------------LPG-AKATARYVHTSPTK ARRVVDLVRGRSASEALDILRFA---------------------------------PQAASTDVYKVVASAVAN----A- ENNH-NLDPATLWIGAAYVDEGPTLKRIRPRAQGRAYRIRKRTSHITVVVESGMKIKKGDTVQIVTGK------DR-GLK GKVIRAIPDQN--KVV--VEGANRVTRHTR--VQQS-SRG-SQS-GGIVTQEAPIHVSNVM-IVDPSD-------GR--P --TRVGYRF---ND--------DGKVR---ISRRTG---AEL--MGQKVNPHGFRLG--IT-SEFTSRWYA------D-K Q--YKAYVGEDVKIRKMM--SKGME-----RAGISRVDIERTQ-G-RLRVDIHTARPGIVIGRRGAEADRIRGDLEKLVQ LNILEVKN---PEIDAQLVAQGVAEQLSSRVSFRRAMRKAMQSAMKS-GAKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGFYEARTNFGRIGVKVWIYMTMTDPIADMLTRVRNANRAYHDRVVM-PHSKIKTHIAEILQQEGYILGWH VED----P---A-EGAVGRTLIVDLKYG---PNR-------E---RSIAGVKRISKPGLRVYAKSTNLPKVLGGLGVAII STSSGLLTDRQAGKRRVGGEVLAYVWMAAQKIRIRLKAYDHEVIDSSARKIVETVTRTGAQVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVISGKMQKTVVVAVEDRVQHPLYG KTIRRTKRVKAHDEN--GTVGVGDRVLLMETRPLSATKRWRVVQILEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNE---KGTKH----VIRTWSRRSTVIPDMLGHTIAVHDGRKHVPVFITE-GMVGH KLGEFAPTRTFRGHV------K--EDR----RSR------RG >ACTINO_Jonesia_denitrificans_DSM_20603 Concatenation of 2 sequences MGIRKYKPTTPGRRDASVADFVE-ITRS------------QP-EKSLVRPLTKTGGRNNSGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPHKLQQGDVVEAGP-N-AD-IKPGNNLPLR NIPTGTVIHAIELRPGGGAKIARSAGASVQLVAK--DGPYAQLRMPSGEIRNVDARCRATVGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQPEG--RTR-RPNKPSD-K-LIVRRR --------------------------------NERPVKA-VLGKKLGMTQVWD-EAGR---------LVPVTVVAVEPNV VTQIR----TVD----N--DGY--AAVQVAT-------GQ--IVTK----------PLKGHFK----------------- ---AG-VTPRRHVTEIRT--------SDSGEY-----SL---GQ-EVTV--G-V-FEAGTKVDVIGTTKGKGFAGVMKRH GFAG-ASASHGAHRNHRK-PGSIGAA-ATPS-RVFKGLRMAGRMGHDRMTVQNLTVHAVDADKG---------------- ----------YVLLKGA-VPGPKGGVVLVRENLTVDILD-ATGNKT-GDAVLPAEIF----DV-AL-NVPLIHQVVVAQQ AAARQGTHATKTRAQ--------VS-GGGRKPY---------KQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPQ-P-RDYSQRTPKKMKAAALRSALSDRARAG----------------R-IHVIDSF--GVTEA-------- --PSTKLVV--HERND--E---ITIKSLRNIESVH-L---------------ITADQLNTYDVLLSDD----VVFTKAAL DGFLPRLKSRYRDEI----RPALHEEFKHENINQVAGLVKVVVNMGVG-DAAKDSKLIEGAIRDLTLITGQKPQVNRARK SIAQFKLREGMPIGAHVTLRGDRMWEFTDRLLSIALPRIRDFRGLSP-KQFDGNGNYTFGLTEQSMFHEID-----PDSI DRVRGMDITFVTS-----------------------AKTDEEGRSLLKRLGFPFMSRIG-K--LPIPVPAGVDVT-I--- -N-G--N-LVTIKGSKGTLEHVI-PAP----IEVARAEDGT--IIV---SR-P--NDERQSR-ALHGLTRSLLANIITGV TQGYEKKLEIVGTGY--RVTAKG-KD--LEFA--LGFSHPVVVTA-P-E-GITFAVE--A-PTKFSVSG-IDKQQVSEVA ANIRKIR------KPEPY---KGKGVRYAGENIRRKAGK----------MIQQESRLRVADNTGAKEILCIRVLG-SGRR Y--AGIGDTIVATVKDAIPG-G-------NVKKGDIVKAVIVRTSKERRRPDGSYIKFDENAAVILK-NDGE-PRGTRIF GPVGRELR-DKRFMKIISLAPEVLLK-L--HDLRPARGA-KKAKTRVG-RGEASK--GKTAGRGTKGTKARYQ---V--- -PARF-E-GGQMPLHMRLPKLRG--FKNVNLDKLVTVDDLVAK-GAVRVK---------VLG--TGE-I-S-V-K-LEV- TVDAVSSSAQEKIQAAGGTI-K---QHH--PSR---SGAS-KGGNVVTFG----------DYGIQAL--TPAYVTNRQIE AARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GKIVFEL--AG-- VPEPLAREAMRRAMHKLPMKCRF-VKAVARQRRHARLRKKI---RGTAVRPRLVVTRSTRHMVAQVVDD---T--AGKTL VSASTL-EVDL-RSFD------G-DKTAKSRKVGELIAER--AKAAG-IDSVVFDRGGNKYH--GRVAAVAEGAREGGLS L--------------------------------------------------------------ME-AMAKARFIRVTPRK ARRVVDLIRGKQATEAVTVLKFA---------------------------------PQAASEPVLKVVQSAIANARVIA- DRDNVAFDETKLVIKTAVVDEGPTLKRFRPRAQGRASQILKRTSHITVVVAPMANIKKGDTVIVIAGK------DK-GKT GRVLQVLRDQD--RVI--VEGVRRVTKHVK----PG-QTARGTRTGGIEVVEAPIHISNVQ-FYDAET-------KR--G --KRLGSRL---EE-----VERNGRVR---VVRGHGDKEKDV--MGQKVHPHGYRLG--IT-TDHRSRWFA-DSTKPG-Q R--YRDYVREDVAIRKLM--SEGLE-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---AEIEAQLVAQGIAEQLASRVSFRRAMRKGMQSALRA-GAKGIRVQYSGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHETVTM-PSSKLKSNIAAILKAEGYIKDWK IED----A---R----VGKSLVIELKYN---TAR-------E---RALAGVRRISKPGLRVYAKSTNLPQVRGGLGVAIL STSSGLLTDKQAAQKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVFCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKLRKTRRGYVVSDKMEKTIVVEVEDRVKHPLYG KVMRRTSKVKAHDEQ--NTAGIGDLVLIMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLQKKVDAQNE---AGTHN----VIKTWSRRSVITPDFLGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFRGHV------K--DDK----KGR------RR >ACTINO_Kineococcus_radiotolerans_SRS30216 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-ITRS------------EP-EKSLVRPLSKTGGRNSSGRITTRH-IGGGHKRA---- YRLIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYV-DGEKRYIIAPAKLKQGDRIENGP-E-AD-IKPGNNLPLR NIPVGTVIHAIEIRPGGGAKIARSAGASVQLVAR--EGRFAQLRMPSGEIRNVDVRCRATIGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-TVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQPEG--RTR-RPGKESD-K-LIVRRR --------------------------------QVR---G-VLGTKLGMTQLWD-ADNR---------IVPVTVVKVEPNV VTQIR----TTT----V--DGY--EAVQLAT-------TA--IATK----------PAAGHFK----------------- ---AG-VAPRRHLVELRT--------TDAADY-----SL---GQ-EVTA--E-A-FATGATVDVVGTTKGKGFAGVMKRH GFHG-VGASHGAHRNHRK-PGSIGGC-ATPG-RVFKGMRMAGRMGAARQTTQNLTVQAVDAEKG---------------- ----------LLLITGA-IPGPRGGLVLVKEAITVPLRT-ADGGSN-GTVELPAKDF----GR-QA-NISLIHQVVTAQL AAARQGTHSTKRRGE--------VR-GGGKKPY---------KQKGTGRAR--------QGS---LR-AP----QF---- TGGGIVHGPK-P-RDYSQRTPKKMKAAALRGALSDRVRHE----------------R-LHVVEGL--AAGET-------- --PSTKLVV--LTRDD--D---VSQKSLRNLDNVH-V---------------LPADQLNTYDVVKSDD----VVFTRAAL DAFVPRLKQRYRDEI----KGQLHEQFSYGNVMQIPGLTKVVVNMGVG-EAARDSKLIDGAVRDLTAITGQKPQITKARK SIAQFKLREGMPIGCHTTLRGDRMWEFLDRLLSLALPRIRDFRGLSP-KQFDGNGNYTFGLNEQSMFHEID-----QDKI DRVRGMDITVVTT-----------------------ATTDDEGRALLRALGFPFMSRIG-R--LPITVPAGVDVT-I--- -D-G--A-AVTVKGPKGELSHTV-AAP----ISVERTEDGT--LQV---TR-P--DDERVSR-SLHGLTRTLISNMVEGV TKGYEKKLEIVGTGY--RVTPKG-SD--LEFA--LGFSHPVVVKA-P-A-GITFAVE--N-NTRFSVAG-IDKQQVGEIA ANIRKLR------KPDPY---KGKGVRYAGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTKKERRRADGSYIRFDENAAVILR-ADGD-PRGTRIF GPVGRELR-EKKFMRIISLAPEVLLK-L--HHLRPAPGS-NTAKTRVG-RGEGSK--GKTAGRGTKGSKARYQ---V--- -PEAF-E-GGQMPLHMRLPKLRG--FKNVNLDKLVGVDELVAK-GAVRVK---------VLG--TGE-I-S-V-A-LQV- TADKFSTSAAEKIAAAGGTT-K---QHH--PTR---RGAA-SGGTRVTFG----------DYGIMAV--EGGYVTNRQIE SARIAITRHI------RRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANIKP-GRVMFEL--SF-- PTEKIATEALTRAIHKLPVKCKI-VKAASLKRRHTRVRKKV---VGTAVRPRLVVTRSTRHVFVQVIDD---A--AGHTL ASASTM-EADL-RA------SGD-DKSAKAKAVGVLVGER--AKAAG-IDAVVFDRGGNRYA--GRVAAIADGAREAGLA L--------------------------------------------------------------ME-AKAQTRYLRVTPQK ARRVVDLVRGKQATEAVAVLSFA---------------------------------PQSAAEPVRKLVESAMANAKFHAD KHSE-AFDPAEYVVKAIHVDEGPTMKRFRPRAQGRAGRILKRTSHITVVVAPKTRIKKGDLVQVITRVRGRRNADGLGKQ GKVLEVIAETD--RVL--VEGVNRIKRHTK-A------RP-GVE-GGIVEREAPIHISNVQ-LVDPET-------KK--P --TRVGIRT---EQVR------DGRIR---VAKRSG---KDI--MGQKVNPFGFRLG--IT-TDHRSRWFA-DSTKTG-Q R--YADYVKEDVAIRRLM--SKGME-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRTELEKLVQ LNILEVKN---PEVDAQLVAQGVAEQLASRVSFRRAMRKGMQTTMRS-GAKGIRVQCAGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFYEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDTVSM-PYSKLKSHIAEILQAEGYITSWT VED----A---E----VGKKLTLDLKFG---PNR-------E---RAIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAIL STSSGLLTDKQANKKGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSARKIVDTVTRTGASVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDIEIKLRKTRRGYVVSDKMQKTVVVEVEDRVKHPLYA KVIRRTTKVKAHDEV--ETAGVGDLVLIAETRPLSATKRWRVVEVLERA------------------------------- -MPRSL-KKGPFVDD-HLQKKVDAQNE---AGTHN----VIRTWSRRSVVTPDFLGHTFAVHDGRKHTPVFVTE-SMVGH KLGEFAPTRTFKGHE------K--DDR----KGR------RR >ACTINO_Kytococcus_sedentarius_541,_DSM_20547 Concatenation of 2 sequences MAIRKHKPTTPGRRGSSAADFVE-VTRS------------TP-EKSLVRPLTKSGGRNASGRITTRH-IGGGHKRA---- YRLIDFR-RA-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPRNLAQGAQVESGP-T-AD-IKPGNNLPLR NIPVGTVIHAIELRPGGGAKIARSAGTRVQLVAK--DGPYAQLRMPSGEIRNVDARCRASIGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGKPEG--RTR-KKGKGSD-K-MIVRRR --------------------------------MQRTVAG-VLGTKLGMTQVWD-EDNR---------LVPVTVVQVAPNV VTQIR----TQD----T--DGY--GAVQIAT-------GD--IVSN----------PLRGHFK----------------- ---AG-VTPRRHVTELRT--------ADSGSY-----EL---GQ-ELTV--E-T-FENGATVDVTGTTKGKGFAGVMKRH GFAG-VSASHGAHRNHRK-PGSIGGC-ATPG-RVFRGTRMAGRMGGERQTTQNLTIHAVDADKG---------------- ----------LLLIKGA-VPGARGGLVLVR-MPTIDIIS-PAGKAT-GSVELPAEIF----DV-AA-NVPLIHQVVVAQL AAARQGTHSTKTRAE--------VR-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGIVHGPQ-P-RDYAQRTPKKMKAAALRGALSDRARHG----------------R-IHVLSAV--LEGDA-------- --PSSKLVV--LERGD--E---LSLMSLRNLQNVH-A---------------LFADQLNTYDVMCADD----VFFTAGAL DAFIPRLKERYRSEI----REALKSEFGYANVMQIPGVTKVVVNMGVG-DAARDSKLIDGAIRDLTTITGQKPRVNRATK SIAQFKLREGMPIGANVTLRGDRMWEFLDRLVSVALPRIRDFRGLSP-KQFDGKGNYTFGLTEQSMFHEID-----QDKI DRVRGMDITVVTT-----------------------AETDDEGRALLRALGFPFMSRIG-R--LPVTVPSGVDVT-I--- -D-G--Q-DVKVKGPKGELSVTI-PGP-I--TAAKNDE-GA--VEL---SR-P--DDERDSR-ARHGLSRSLVQNMVVGV TEGYSKTLEINGTGY--RVVAKG-SD--LEFA--LGYSHPILVKA-P-E-GITFAVE--S-PTRFSVSG-IDKQLVGEVA ANIRKLR------KPDPY---KAKGVRYEGEHIRRKVGK----------MIQQESRLRVADNTGAKEILCIRVLG-SGRR Y--AGIGDTIVASVKDAIPG-G-------NVKKGDVVKAVIVRTTKERRRPDGSYIRFDENAAVILK-ADGE-PRGTRIF GPVGRELR-DNQFMRIVSLAPEVILK-V--HDLRPAPGA-KKAKTRVG-RGEASK--GKTAGRGTKGTKARYQ---V--- -PERF-E-GGQTPLHMRLPKLRG--FKNVNVDQIVNAATLVEA-GLIRVK---------VLG--SGE-I-S-V-A-VNV- TADKFSASAEQKISAAGGST-K---QHH--PKR---GGAS-KGGTQLAFG----------DYGIQAL--GPAYVTNRQIE SARIAMTRYI------KRGGKVWINIYPDRPLTKKPAEVRMGSGK---------GSPEWWVANVKP-GRIMFEL--SG-- VTDDVAREALRLAMHKLPMKCRI-VNVAARDRRHARLRKKV---SGTAERPRLAVHRSSRHMFVQVIDD---V--QGKTL ASASTM-ETEL-RG------AEG-DKSAKARKVGELVAER--AKAAG-VEAVVLDRGGNRYA--GRVAAVADGAREGGLA L--------------------------------------------------------------ME-AKAQARYVRVTPMK ARRVVDLIRGKQASEALAVLQFA---------------------------------PQGASEPVMKVLQSAIANARFMA- DRDATAFDESSLVISEAYVDEGPSMKRFRPRAQGRASKILKRTSHITVLVSQKMKIKKNDLVQVVTGRKQENGGDR-GKT GRVIEVYPERN--RVL--VEGINRVTKHTK----AG--VG-GGA-GGIQTVEAPIHVSNVA-LVDPET-------NT--P --TRVRTRVENVER--------NGRTR---VSVRSG---KDL--MGQKINPHGFRLG--IT-TDHKSRWFADSSA--EGQ R--YADFVGEDVAIRKLL--SSGME-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRLRGQLEKLVQ LNILEVKN---PEAVAQLVAQGIAEQLSARVSTRRAMKKGIQSAQRA-GAKGIRVQCSGRLGGAEMSRTEFYREGRVPL- -HTLRANIDYGFYEARTTFGRIGVKVWIYMTMTDPIADMLTRVRNANSAQHDEVRM-PFSKLKAHIADILKAEGYIGEWT EEE----A---E----VGKTLVISLKYG---PNR-------E---RSIAGVRRVSKPGLRVYAKSTNLPKVLGGLGIAIL STSSGLLTDKQAAAKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVFCVIRS PHKYKDSR-EHFEMRTHKRLIDIVDPTPKAVDSLMRLDLPADVNIEIKLRKERRGYVVSDKMEKTITVALEEHVKHALYG KVIRKTKKVKAHDEE--NTAGVGDLVRIAETRPTSATKRWRLVEVVEKA------------------------------- -MPRSL-KKGPFVDD-HLAKKVDAQNE---AGTKN----VIKTWSRRSMITPDMLGHTLAVHDGRKHVPVFVTE-SMVGH KLGEFAPTKTFRGHV------K--DDR----KGR------R- >ACTINO_Leifsonia_xyli_subsp_xyli_str_CTCB07 Concatenation of 2 sequences MAIRNYKPTTPGRRGSSVADFAE-ITRS------------NP-EKSLLRPLSKSGGRNNQGRITTRH-IGGGHKRQ---- YRVIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHFL-DGTKRYILAPAGLKQGNIVESGA-G-AD-IKPGNNLPLC NIPTGTVVHAIELKPGGGAKLARSAGSSVRLVAK--DGPYAQLRLPSGEVRNVDARCRATIGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-HPNKESD-K-LIVRRR --------------------------------DTKTSRG-LLGKKLGMTQVWD-ENDT---------LIPVTVIEITPNV VTQVR----TPE----A--DGY--NAVQIAY-------GQ--IVNK----------PSAGHFK----------------- ---AG-VTPRRHLTEVRT--------ADAAEY-----SA---GQ-ELTV--DGT-FEAGQLVDVVGTSKSKGFAGVMKRH NFQG-VSASHGAHRNHRK-PGSIGAS-STPS-RVFKGMRMAGRMGGERVTVLNLKVQAIDAEKG---------------- ----------LLLVKGA-VPGARGRIVFVRMATSIDVVD-LKGKKA-GSIELPDSLF----DV-QT-NIPLIHQVVTAQL AAARQGTHKTKNRGE--------VS-GAGRKPF---------KQKGTGRAR--------QGS---IR-AP----QM---- TGGGIVHGPT-P-RDYSQRTPKKMIAAALLGALSDRARGS----------------R-IHAVQAF--TAGEA-------- --PSTKLVV--LERDD--E---LAFKSVRNIASVH-A---------------LTYDQLNAYDVLVSDD----IVFTQAAL EGFIPRLKQKYKTEI----AANLSKDFGFTNVHQVPGLVKIVVNMGMG-EAARDGKVIDGAINDLTLITGQKPQVTKARK SIAQFKLREGQPIGAHVTLRGDRMWEFLDRLLSLALPRIRDFRGLSD-KQFDGNGNYTFGLTEQSMFHEIN-----QDRI DRVRGMDITVVTT-----------------------AKNDEEGRALLKQLGFPFMSRIG-R--LPIDVPAGVDVK-I--- -D-G--Q-AVTVKGPKGELSLTV-ASP----IEVKLEE-GQ--VLV---TR-P--DDERESR-SLHGLTRTLLNNNIVGV TQGYSKGLEIVGTGY--RVAQKG-AG--VEFA--LGFSHPVTVEP-P-A-GITFTVE--G-NNKLTVAG-IDKQAVGEVA ANIRKIR------KPEPY---KGKGVRYAGEVVRRKAGK----------MIQQESRLKVADNTGAKELLTIRVLG-SGRR Y--AGLGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTRKNTRRTDGSYIKFDENAAVILK-NDGD-PRGTRIF GPVGRELR-DKKFMKIISLAPEVLLK-V--HHLRPAAGA-KKEKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---V--- -RPGF-Q-GGQLPFHMRTPKLRG--FKNVNLEKLVTVAALVAK-GAVRVK---------VLG--NGD-I-A-V-K-LNV- AVDKVSGSAEQKIVAAGGSV-K---QHH--PGR---SGQA-TGGTKVSFG----------EFGIQAL--TPAYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEV--SG-- VSEDLAREAMSRAIHKLPLKARI-IKAAARGRRHTRLRKKI---VGTELRPRLVVTRSARHVFVQVVDD---A--QGRTL ASASTM-EADL-RGFD------G-DKTAKARKVGELVAER--AKSAG-VEAVVFDRGGSQYA--GRVAAVAEGAREGGLN L-------------------------------------------------------------MVE-SIARVRHIRVTPMK ARRVVNMIRGKQAQEALAILKFA---------------------------------PQGASEPVYKLVASAIANARVKA- DQSNTYLDEQDLYVSRAFVDEGTTLKRFQPRAQGRAFRINKRTSHITVVLATMANIKKGDLVQVITGRSQARGGDR-GKQ GRVIEVLVEKN--RVI--VEGVNFVTKHVR-VGQTQ--RG-TKT-GGIETHEASIHVSNVA-LVDPET-------KK--P --TRVGFRT---ET--VTK---DGRVR---YAKKSG---KDL--MGQKVNPYGFRLG--IT-TDHVSRWFS-DSTKKG-Q R--YSDYLAEDVKIRTLL--KTSLD-----RAGVSRIEIERTR-D-RVRVDIHTARPGIVIGRRGAEAERIRADLEKLIQ LNILEVKN---PEADAQLVAQGIAEQLAARVAFRRAMRKGLQGAQRA-GSKGVRIQVSGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFYEAKTTFGRLGVKVWMYMTMTDPVADMLTRLRNANSAHHDTVSM-PHSKLKVHIAEILTTEGYISGWE VAD----A---R----VGQTLTLSLKFG---PNR-------E---RSIAGIKRVSKPGLRVYAKSTELPKVLGGLGVAIL STSSGLLTDRQAEKKGVGGEVLAYVWMAGQKIRIRLKSYDHAGLDTSARKIVDTVTRAGATVVGPVPLPTEKNVVCVIRS PHKYKDSR-EHFEMRTHKRLIDIVDPTPKAVDSLMRLDLPADVNIEIKLRKARRGYVVSDKMDKTIVVEVEDRVKHPLYG KVLRRTSKVKAHDES--NVAGIGDLVLINETRPLSASKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLFRKVVAANE---ANSKN----VIKTWSRRSMIVPAMLGHTIAVHDGRKHIPVFVTE-TMVGH KLGEFAPTRTFRGHV------K--DDK----RGR------RR >ACTINO_Mycobacterium_avium_104 Concatenation of 2 sequences MAIRKYKPTSPGRRGASVSDFSE-VTRS------------TP-EKSLVRPLHGHGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RN-DK-DGVNAKVAHIEYDPNRTANIALLHFL-DGEKRYIIAPQGLSQGDVVESGP-N-AD-IKPGNNLPLR NIPAGTVIHAVELRPGGGAKLARSAGSSIQLLGK--EGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-HPNKASN-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNR---------VVPVTVVKAGPNV VTRIR----TPE----Q--DGY--SAVQLAY-------GE--IVNK----------PVTGQYA----------------- ---AG-INPRRFLAELRL-----DNPDAAAEY-----QV---GQ-ELTA--E-I-FTDGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVQNLLVHKVDTENG---------------- ----------VLLIKGA-VPGRTGGLVMVRMALKLDVKA-PGGKVE-GSIELPAELF----DA-PA-NIALMHQVVTAQR AAARQGTHSTKTRGD--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VSGQT-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL RAYIPRLKERYRNEI----RDSLQQQFGYANVMQIPTVTKVVVNMGIG-EAARDAKLINGAVNDLALITGQRPEIRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQSVFHEID-----VDKI DRVRGMDINVVTS-----------------------ATTDDEGRALLRALGFPFMSRIG-K--QPVPVPAGVDVT-I--- -D-G--Q-KVSVKGPKGTLDLTV-AEP----ITVSRNDDGA--IVV---TR-P--NDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--S-PTKFSISG-IDKQKVGQIS ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLIK-L--HDLKPARGS-KTPRTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDELVAK-GAVRVK---------VLG--DGK-L-T-V-K-VEV- SAHKFSGSAREKITAAGGSV-K---QHH--PRQ---RGIA-SGGTAVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINVFPDRPLTKKPAETRMGSGK---------GSPEWWVVNVKP-GRVLFEL--SY-- PNEQTARAALTRAIHKLPIKARI-VRRVSRLRRHARLRKKI---AGTPERPRLVVNRSARHIHVQLVND---E--NGTTV AAASSI-EDDV-RS------LQG-DKKARSVRVGQLIAER--AKAAG-IDSVVFDRGGYTYG--GRIAALADAARENGLQ F-------------------------------------------------------------FPS-AVAKARFVRVSPRK ARRVIDLVRGRSVTDALDILRWA---------------------------------PQAASEPVAKVIASAAAN----A- QNNN-GLDPATLVVATVYADEGPTAKRIRPRAQGRAFRIRKRTSHITVVVES-MKVRKGDTVLVIAGK------DK-GAK GKVLKAYPDRE--RVL--VEGVNRIKKHTA-ISTNQ--RG-AQS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --ARVGYRL---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YADYVKEDVAIRRLL--STGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVRN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIY--MTDPIADFLTRLRNANSAYHDEVTL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLIVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRVKHPLYG KIIRTTKKVKAHDEN--SIAGIGDRVSLMETRPTSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLLKKVDAQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KAK------RR >ACTINO_Mycobacterium_avium_subsp_paratuberculosis_K-10 Concatenation of 2 sequences MAIRKYKPTSPGRRGASVSDFSE-VTRS------------TP-EKSLVRPLHGHGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RN-DK-DGVNAKVAHIEYDPNRTANIALLHFL-DGEKRYIIAPQGLSQGDVVESGP-N-AD-IKPGNNLPLR NIPAGTVIHAVELRPGGGAKLALSAGSSIQLLGK--EGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-HPNKASN-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNR---------VVPVTVVKAGPNV VTRIR----TPE----Q--DGY--SAVQLAY-------GE--IVNK----------PVTGQYA----------------- ---AG-INPRRFLAELRL-----DNPDAAAEY-----QV---GQ-ELTA--E-I-FTDGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVQNLLVHKVDTENG---------------- ----------VLLIKGA-VPGRTGGLVMVRMALKLDVKA-PGGKVE-GSIELPAELF----D--APANIALMHQVVTAQR AAARQGTHSTKTRGD--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VSGQT-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL RAYIPRLKERYRNEI----RDSLQQQFGSANVMQIPTVTKVVVNMGIG-EAARDAKLINGAVNDLALITGQRPEIRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLTSIALPRIRDFRGLSS-KQFDGVGNYTFGLAEQSVFHEID-----VDKI DRVRGMDINVVTS-----------------------ATTDDEGRALLRALGFPFMSRIG-K--QPVPVPAGVDVT-I--- -D-G--Q-KVSVKGPKGTLDLTV-AEP----ITVSRNDDGA--IVV---TR-P--NDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--S-PTKFSISG-IDKQKVGQIS ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLIK-L--HDLKPARGS-KTPRTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDELVAK-GAVRVK---------VLG--DGK-L-T-V-K-VEV- SAHKFSGSAREKITAAGGSV-K---QHH--PRQ---RGIA-SGGTAVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINVFPDRPLTKKPAETRMGSGK---------GSPEWWVVNVKP-GRVLFEL--SY-- PNEQTARAALTRAIHKLPIKARI-VRRVSRLRRHARLRKKI---AGTPERPRLVVNRSARHIHVQLVND---E--NGTTV AAASSI-EDDV-RS------LQG-DKKARSVRVGQLIAER--AKAAG-IDSVVFDRGGYTYG--GRIAALADAARENGLQ F-------------------------------------------------------------FPS-AVAKARFVRVSPRK ARRVIDLVRGRSVTDALDILRWA---------------------------------PQAASEPVAKVIASAAAN----A- QNNN-GLDPATLVVATVYADEGPTAKRIRPRAQGRAFRIRKRTSHITVVVES-MKVRKGDTVLVIAGK------DK-GAK GKVLKAYPDRE--RVL--VEGVNRIKKHTA-ISTNQ--RG-AQS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --ARVGYRL---DE-E------TGRVR---ISKRNG---KDI--MGQKINPYGFRLG--IT-TDWKSRWYA------D-K Q--YADYVKEDVAIRRLL--STGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVRN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIGYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLIVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRVKHPLYG KIIRTTKKVKAHDEN--SIAGIGDRVSLMETRPTSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLLKKVDAQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KAK------RR >ACTINO_Mycobacterium_bovis_AF2122/97 Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRMIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NANKSSN-K-FIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ESNR---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PLTGQYA----------------- ---AG-VNPRRYLAELRL-----DDSDAATEY-----QV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVLNLLVHKVDAENG---------------- ----------VLLIKGA-VPGRTGGLVMVRKTLKIDVKT-PAGKVD-GAIELPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGE--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VEGQN-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDALRKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVNDLALITGQKPEVRRARK SIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQAVFHEVD-----VDKI DRVRGMDINVVTS-----------------------AATDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDVT-I--- -E-G--Q-SISVKGPKGTLGLTV-AEP----IKVARNDDGA--IVV---TR-P--DDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIA ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLLK-L--HDLRPARGS-KTARTRVG-RGDGSK--GKTAGRGTKGTRARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDDLVAK-GAVRVK---------VLG--DGK-L-T-A-K-VDV- SAHKFSGSARAKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEGVARAALTRAIHKLPIKARI-IRRISRLRRHTRLRKKL---SGTAERPRLVVHRSARHIHVQLVND---L--NGTTV AAASSI-EADV-RG------VPG-DKKARSVRVGQLIAER--AKAAG-IDTVVFDRGGYTYG--GRIAALADAARENGLS F-------------------------------------------------------------YPS-AVAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASGPVAKVIASAAAN----A- QNNG-GLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVISGK------DK-GAK GKVLQAYPDRN--RVL--VEGVNRIKKHTA-ISTTQ--RG-ARS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLVIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDED--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_bovis_BCG_str_Pasteur_1173P2 Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRMIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NANKSSN-K-FIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ESNR---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PLTGQYA----------------- ---AG-VNPRRYLAELRL-----DDSDAATEY-----QV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVLNLLVHKVDAENG---------------- ----------VLLIKGA-VPGRTGGLVMVRKTLKIDVKT-PAGKVD-GAIELPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGE--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VEGQN-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDALRKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVNDLALITGQKPEVRRARK SIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQAVFHEVD-----VDKI DRVRGMDINVVTS-----------------------AATDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDVT-I--- -E-G--Q-SISVKGPKGTLGLTV-AEP----IKVARNDDGA--IVV---TR-P--DDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIA ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLLK-L--HDLRPARGS-KTARTRVG-RGDGSK--GKTAGRGTKGTRARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDDLVAK-GAVRVK---------VLG--DGK-L-T-A-K-VDV- SAHKFSGSARAKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEGVARAALTRAIHKLPIKARI-IRRISRLRRHTRLRKKL---SGTAERPRLVVHRSARHIHVQLVND---L--NGTTV AAASSI-EADV-RG------VPG-DKKARSVRVGQLIAER--AKAAG-IDTVVFDRGGYTYG--GRIAALADAARENGLS F-------------------------------------------------------------YPS-AVAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASGPVAKVIASAAAN----A- QNNG-GLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVISGK------DK-GAK GKVLQAYPDRN--RVL--VEGVNRIKKHTA-ISTTQ--RG-ARS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLVIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDED--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_gilvum_PYR-GCK Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVSDFAE-ITRD------------HP-EKSLIRPLHGKGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVDAKVAHIEYDPNRTANIALLHYL-DGEKRYIIAPQGLKQGAIVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKMARSAGASIQLLGK--EGTYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPNKASD-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TTE----R--DGY--SAVQLAY-------GE--IVNK----------PVTGQFA----------------- ---AG-VNPRRHLAELRL----ADNEDAGALY-----EV---GQ-ELTA--E-I-FADGAYVDVTGTSKGKGFAGTMKRH GFKG-QGASHGAQAVHRR-PGSIGGC-ATPG-RVFKGTRMSGRMGSDRVTTQNLKVHKVDAENG---------------- ----------VLLIKGA-IPGRNGGLVVVRANKTIDVVT-PAGKKD-GTVELPAALF----DA-EP-NIALMHQVVTAQL AAKRQGTHATKTRAM--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPQ-P-RDYSQRTPKKMIAAALRSALSDRARND----------------R-IHAITEV--VEGQS-------- --PSTKLVV--IGRAD--E---TSALSVRNLPGVH-V---------------ISPDQLNTYDVLKADD----VVFSVEAL NAYIPRLKQRYREEI----REQLLKEFGYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAVNDLMLITGQKPEIRKARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLISISLPRIRDFRGLSG-KQFDGTGNYTFGLTEQSVFHEID-----VDSI DRPRGMDITVVTS-----------------------ATNDDEGRALLRALGFPFMSRIG-K--QPVPVPAGVDVT-I--- -S-G--Q-NVSVKGPKGTLTLDV-AEP----IEVSRNDDGA--IVV---TR-P--NDERRNR-SLHGLSRTLIANLVTGV TEGYTTKMEIFGVGY--RVVAKG-SN--LEFA--LGYSHPVLINA-P-E-GVTFAVE--T-PTKFSISG-IDKQAVGQIA ANIRRLR------KSDPY---KGKGIRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVIVRTVKERRRADGSYIRFDENAAVIIK-NDND-PRGTRIF GPVGRELR-EKKFMKIVSLAPEVLIK-L--HDLRPAPGE-KTKKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PVMF-E-GGQMPIHMRLPKLKG--FRNVNVGDLVGVDELVAK-GLVRVK---------VLG--DGK-L-S-A-K-VDI- TAHKFSGSAREAITAAGGSV-K---QHH--PRQ---RGIA-SGGTSVSFG----------DYGIQAM--GHAYITNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PDEKIAREALTRAIHKLPIKARI-VRRTSRLRRHARLRKKV---SGTAERPRLVVNRSSRHIHVQLVDD---L--AGVTL AAASSI-EGDV-RA------TDG-DKKAASARVGQLIAER--AKAAG-IEEVVFDRGGYTYG--GRIAALADAARESGLK F-------------------------------------------------------------YPS-ASAKARFVRVSPTK ARRVIDLVRGKSVEDALDILRWA---------------------------------PQAASEPVAKVIASAAAN----A- QNNE-GLDPSTLVVATVFADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVES-MKVRKGDTVLVISGK------DK-GAK GKVLVAYPDRN--KVL--VEGVNRIKKHTA-ESRTE--RG-AAS-GGIVTQEAPISVSNVM-LLD-SD-------GK--P --TRVGYRK---DD-E------TGNVR---IAKSNG---KDL--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YADYIKEDVAIRKLL--ATGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESRAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKIKANIAEILKSEGYISDYR TED----A---R----VGKSLVVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLRTDRQASREGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTAIGYVVSDKMQKTIVVELESRKSHPLYG KIIRTTTKVKAHDEN--ESAGIGDRVSLMETRPTSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KAK------RR >ACTINO_Mycobacterium_leprae_TN Concatenation of 2 sequences MAIRKYKPTTSGRRGASVSDFTD-ITRT------------KP-EKALMRSLHGHGGRNVHGRITTRH-KGGGHKRA---- YRLIDFR-RN-DT-DGVNAKVAHIEYDPNRTANIALLHFL-DGKKRYILAPQGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--ESSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPNKSSN-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNR---------VVPVTVVKAGPNV VTRIR----TLE----R--DGY--SAVQLAY-------GE--IVNK----------PVTGQYS----------------- ---AG-VNPRRYLAELRL-----DHPDAAAEY-----EV---GQ-ELTA--E-I-FADATYVDVTGTSKGKGFSGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVQNLLVHKVDTENG---------------- ----------VLLIKGA-VPGRTGGLVMVRNIRKIDVKT-PDGKVD-GTIELPAELF----DA-PA-NIALMHQVVTAQR AAARQGTHSTKTRGD--------VS-GGGRKPY---------RQKGTGRAR--------QGS---MR-AP----QF---- TGGGIVHGPK-L-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAVTEL--VVGKT-------- --PSTKLVV--IGRSD--E---TGAKSVRNLPGVH-L---------------LSPDQLNTYDVLRADD----LVFSVEAL NSYIPRLKQRYRSEI----REALNKQFSYGNVMQIPTVVKVVVNMGVG-DAARDAKLINGAVSDLALITGQKPEVRKARK SIAQFKLREGMPIGVRVTLRDDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQSVFHEID-----VDKI DRVRGMDINVVTS-----------------------ATTDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDIT-I--- -D-G--Q-NVLVKGPKGTLDLTV-AEP----IMLARNDEGA--IVV---TR-P--DNERRNR-SLHGLSRTLVSNLVTGV TQGYTVSMEIFGVGY--RAQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--S-PTKFTITG-IDKQKVGQIS ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK-------------------MADNTGAKEILCIRVLG-SSRR Y--ASIGDVIVGTVKDAIPG-G-------NVKRGDVVKAVVVRTAKECRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLIK-L--HDLQPARGS-KTTRTRVG-RGEASK--GKTAGRGTKGTKARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIISVNDLVAK-KAIRVK---------ILG--DGK-L-T-V-K-VTL- SAHKFSGSARHKITVAGGSV-K---QHH--PRQ---RGIA-SGGTKVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVVNVKP-GRVLFEL--SY-- PNEQTARAALTRAIHKLPIKARI-VRRVSRLRRHARLRKKV---SGTSERPRLVVNRSARHIHVQLVND---V--TGTTV AAASSI-EADV-RG------LQG-DKKVRSVRVGQLIAER--AKAAG-INTVVFDRGGYTYG--GRIAALADSVRENGLN F-------------------------------------------------------------FPS-AIAKARFVRVSPRK ARRVIDLVRGRSVADALDILRWA---------------------------------PQAASEPVARVIASAAAN----A- QNNN-GLDPETLVVATVYAGEGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVIAGK------DK-GAK GKVLQAYPARN--RVL--VEGVNRIKKHTA-ISANQ--RG-AQA-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TDRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TGWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--STGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLHEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTV-PHSNIKANIAQILKNEGYIRDFR TED----A---R----VGKSLIIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSINLPRVLGGLGVVII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGANVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKMRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDEN--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KAK------RR >ACTINO_Mycobacterium_smegmatis_str_MC2_155 Concatenation of 2 sequences MGIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGKGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVNAKVAHIEYDPNRTANIALLHYL-DGEKRYIIAPQGLKQGDVIESGA-N-AD-IKPGNNLPLR NIPAGTVIHAVELRPGGGAKLARSAGVSIQLLGK--EGTYAALRMPSGEIRRVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPNKPSD-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TTE----R--DGY--SAVQLAY-------GE--IVIK----------PVAGQFA----------------- ---AG-VNPRRHVAELRL-----DDEAAVAEY-----EV---GQ-ELTA--E-I-FSDGAYVDVTGTSKGKGFAGTMKRH GFRG-QGAAHGAQAVHRR-PGSIGGC-ATPG-RVFKGTRMSGRMGNDRVTTQNLKVHKVDAENG---------------- ----------VLLIKGA-IPGRNGGLVVVRMTLKVDVKT-PAGKTD-GSVELPAELF----DV-EP-NIALMHQVVTAQL AAKRQGTHSTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGTVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARND----------------R-IHAVTEL--VEGQT-------- --PSTKLVV--IGRTD--E---VGAKSVRNLPGVH-V---------------ISPDQLNTYDVLNADD----VVFSVEAL NAYIPRLKQRYREEI----REALQQEFNYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAINDLALITGQKPEVRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLISIALPRIRDFRGLSP-KQFDGTGNYTFGLNEQSMFHEID-----VDSI DRPRGMDITVVTT-----------------------ATNDAEGRALLRALGFPFMSRIG-K--QPVPVPSGVDVT-I--- -N-G--Q-NLSVKGPKGTLTLDV-AEP----ISVSRAEDGA--IVV---TR-P--DDERRSR-SLHGLSRTLIANLVTGV TEGYTQKMEIFGVGY--RVQLKG-QN--LEFA--LGYSHPVLIEA-P-E-GITFAVE--S-PTKFSVSG-IDKQKVGQIS AVIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIK-NDND-PRGTRIF GPVGRELR-EKKFMKIVSLAPEVLIK-L--HDLKPAPGE-KKAKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PVMF-E-GGQMPIHMRLPKLKG--FKNVNVGDIVGVDELVAK-GLVRVK---------VLG--DGK-L-T-V-K-VDV- TANKFSGSAREAITAAGGSA-K---QHH--PEQ---RGIA-SGGTSVSFG----------DYGIQAL--EHAYITNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PDEKTARDALTRAIHKLPIKARI-VRRNARLRRHARLRKKV---AGTAEVPRLVVNRSARHIHVQLVND---L--NGTTL AAASSI-EADV-RA------IDG-DKKAHSVRVGQLIAER--AKAAG-VETVVFDRGGYTYG--GRIAALADAAREAGLK F-------------------------------------------------------------FPS-ATAKARYVRVSATK ARRVIDLVRGKSVEEALDILRWA---------------------------------PQAASEPVAKVIASAAAN----A- QNNE-GLDPSTLVVATVYADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVES-MKVHKGDTVLVISGK------DK-GAK GKVLVAYPDRN--KVL--VEGVNRIKKHTA-VSANE--RG-ASS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRVGYRI---DD-E------TGKVR---IAKTNG---KDI--MGQKINPHGFRLG--IT-TEWKSRWYA------D-K Q--YKDYVKEDVAIRKLL--ATGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKLKANIAEILKREGYISDYR TED----A---R----VGKSLVVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTAIGYVVSDKMQKTIVVELEDRKSHPLYG KIIRTTKKVKAHDEN--GEAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_sp_JLS Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGKGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVDAKVAHIEYDPNRTANIALLHYL-DGEKRYIIAPYGLKQGAIVESGA-N-AD-IKPGNNLPLR NIPAGTVIHAVELRPGGGAKLARSAGVSIQLLGK--EGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPNKPSD-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQIAY-------GE--IVNK----------PVTGQFA----------------- ---AG-VNPRRHLAELRL-----DDESAAADY-----EV---GQ-ELTA--E-V-FSDGAYVDVTGTSKGKGFAGTMKRH GFKG-QGAAHGAQAVHRR-PGSIGGC-ATPG-RVFKGTRMSGRMGSDRVTTQNLVVHKVDAANG---------------- ----------VLLIKGA-IPGRNGGLVMVRMATTIEVKT-PAGTTD-GSVELPAELF----DV-EA-NIALMHQVVTAQL AAKRQGTHSTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGTVHGPQ-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAVTEL--VEGQT-------- --PSTKLVV--IGRAD--E---TSERSVRNLPGVH-I---------------ISPDQLNTYDVLKADD----VVFSVEAL NAYIPRLKQRYREEI----RESLQQQFGYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAVNDLALITGQKPEIRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLVAIALPRIRDFRGLNP-KQFDGTGNYTFGLTEQSMFHEID-----VDSI DRPRGMDITVVTS-----------------------ATTDDEGRALLRALGFPFMSRIG-K--QPVPVPAGVDVT-I--- -E-G--Q-NVSVKGPKGTLSLAV-AEP----IVVARDDEGA--IVV---TR-P--NDERRNR-SLHGLSRTLVANLVEGV TQGYTTKMEIYGVGY--RVALKG-SN--LEFA--LGYSHPVVIEP-P-E-GITFAVE--T-PTKFSVSG-IDKQKVGQIS AIIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKEAIPG-A-------NVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIK-NDND-PRGTRIF GPVGRELR-EKRFMKIVSLAPEVLIK-L--HDLRPAPGS-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PSTF-E-GGQMPIHMRLPKLKG--FRNINVGDLIGVDELVAS-GAVRVK---------VLG--DGK-L-A-A-A-VNV- TAHKFSDSAREKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVSFG----------DYGIQAL--EHAYITNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PDEKTARDALTRAIHKLPIKARI-VRRRDRIRRHARLRKKV---SGTAQRPRLVVNRSSRHIHVQLVDD---L--TGTTL AAASSI-EADV-RA------VDG-DKKAHSVRVGQLIAER--AKAAG-IDEVVFDRGGYSYG--GRIAALADAAREGGLK F-------------------------------------------------------------YPN-AMAVARYVGISASK ARRVIDLVRGKSVEEALDILRWA---------------------------------PQQASEPVAKVIASAAAN----A- QNNE-GLDPSTLVVATIHADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVES-MKVHKGDTVLVVSGK------DK-GAK GKVIQAYPTRN--KVL--VEGVNRIKKHTA-VSSNE--RG-ASS-GGIVTQEAPIHVSNVM-VVD-SD-------GN--P --TRIGYRV---DE-E------TGKVR---VSKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YKDYVKEDVAIRRLL--ATGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESVAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKIKANIAEILKSEGYISDYR TED----A---R----VGKSLVVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARSGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTAIGYVVSDKMEKTIVVELESRKSHPLYG KIIRTTSKVKAHDEN--GDAGVGDRVSLMETRPLSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQND---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_sp_KMS Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGKGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVDAKVAHIEYDPNRTANIALLHYL-DGEKRYIIAPYGLKQGAIVESGA-N-AD-IKPGNNLPLR NIPAGTVIHAVELRPGGGAKLARSAGVSIQLLGK--EGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPNKPSD-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQIAY-------GE--IVNK----------PVTGQFA----------------- ---AG-VNPRRHLAELRL-----DDESAAADY-----EV---GQ-ELTA--E-V-FSDGAYVDVTGTSKGKGFAGTMKRH GFKG-QGAAHGAQAVHRR-PGSIGGC-ATPG-RVFKGTRMSGRMGSDRVTTQNLVVHKVDAANG---------------- ----------VLLIKGA-IPGRNGGLVMVRMATTIEVKT-PAGTTD-GSVELPAELF----DV-EA-NIALMHQVVTAQL AAKRQGTHSTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGTVHGPQ-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAVTEL--VEGQT-------- --PSTKLVV--IGRAD--E---TSERSVRNLPGVH-I---------------ISPDQLNTYDVLKADD----VVFSVEAL NAYIPRLKQRYREEI----RESLQQQFGYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAVNDLALITGQKPEIRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLVAIALPRIRDFRGLNP-KQFDGTGNYTFGLTEQSMFHEID-----VDSI DRPRGMDITVVTS-----------------------ATTDDEGRALLRALGFPFMSRIG-K--QPVPVPAGVDVT-I--- -E-G--Q-NVSVKGPKGTLSLAV-AEP----IVVARDDEGA--IVV---TR-P--NDERRNR-SLHGLSRTLVANLVEGV TQGYTTKMEIYGVGY--RVALKG-SN--LEFA--LGYSHPVVIEP-P-E-GITFAVE--T-PTKFSVSG-IDKQKVGQIS AIIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKEAIPG-A-------NVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIK-NDND-PRGTRIF GPVGRELR-EKRFMKIVSLAPEVLIK-L--HDLRPAPGS-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PSTF-E-GGQMPIHMRLPKLKG--FRNINVGDLIGVDELVAS-GAVRVK---------VLG--DGK-L-A-A-A-VNV- TAHKFSDSAREKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVSFG----------DYGIQAL--EHAYITNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PDEKTARDALTRAIHKLPIKARI-VRRRDRIRRHARLRKKV---SGTAQRPRLVVNRSSRHIHVQLVDD---L--TGTTL AAASSI-EADV-RA------VDG-DKKAHSVRVGQLIAER--AKAAG-IDEVVFDRGGYSYG--GRIAALADAAREGGLK F-------------------------------------------------------------YPN-AMAVARYVGISASK ARRVIDLVRGKSVEEALDILRWA---------------------------------PQQASEPVAKVIASAAAN----A- QNNE-GLDPSTLVVATIHADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVES-MKVHKGDTVLVVSGK------DK-GAK GKVIQAYPTRN--KVL--VEGVNRIKKHTA-VSSNE--RG-ASS-GGIVTQEAPIHVSNVM-VVD-SD-------GN--P --TRIGYRV---DE-E------TGKVR---VSKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YKDYVKEDVAIRRLL--ATGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESVAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKIKANIAEILKSEGYISDYR TED----A---R----VGKSLVVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARSGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTAIGYVVSDKMEKTIVVELESRKSHPLYG KIIRTTSKVKAHDEN--GDAGVGDRVSLMETRPLSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQND---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_sp_MCS Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGKGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVDAKVAHIEYDPNRTANIALLHYL-DGEKRYIIAPYGLKQGAIVESGA-N-AD-IKPGNNLPLR NIPAGTVIHAVELRPGGGAKLARSAGVSIQLLGK--EGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPNKPSD-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQIAY-------GE--IVNK----------PVTGQFA----------------- ---AG-VNPRRHLAELRL-----DDESAAADY-----EV---GQ-ELTA--E-V-FSDGAYVDVTGTSKGKGFAGTMKRH GFKG-QGAAHGAQAVHRR-PGSIGGC-ATPG-RVFKGTRMSGRMGSDRVTTQNLVVHKVDAANG---------------- ----------VLLIKGA-IPGRNGGLVMVRMATTIEVKT-PAGTTD-GSVELPAELF----DV-EA-NIALMHQVVTAQL AAKRQGTHSTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGTVHGPQ-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAVTEL--VEGQT-------- --PSTKLVV--IGRAD--E---TSERSVRNLPGVH-I---------------ISPDQLNTYDVLKADD----VVFSVEAL NAYIPRLKQRYREEI----RESLQQQFGYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAVNDLALITGQKPEIRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLVAIALPRIRDFRGLNP-KQFDGTGNYTFGLTEQSMFHEID-----VDSI DRPRGMDITVVTS-----------------------ATTDDEGRALLRALGFPFMSRIG-K--QPVPVPAGVDVT-I--- -E-G--Q-NVSVKGPKGTLSLAV-AEP----IVVARDDEGA--IVV---TR-P--NDERRNR-SLHGLSRTLVANLVEGV TQGYTTKMEIYGVGY--RVALKG-SN--LEFA--LGYSHPVVIEP-P-E-GITFAVE--T-PTKFSVSG-IDKQKVGQIS AIIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKEAIPG-A-------NVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIK-NDND-PRGTRIF GPVGRELR-EKRFMKIVSLAPEVLIK-L--HDLRPAPGS-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PSTF-E-GGQMPIHMRLPKLKG--FRNINVGDLIGVDELVAS-GAVRVK---------VLG--DGK-L-A-A-A-VNV- TAHKFSDSAREKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVSFG----------DYGIQAL--EHAYITNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PDEKTARDALTRAIHKLPIKARI-VRRRDRIRRHARLRKKV---SGTAQRPRLVVNRSSRHIHVQLVDD---L--TGTTL AAASSI-EADV-RA------VDG-DKKAHSVRVGQLIAER--AKAAG-IDEVVFDRGGYSYG--GRIAALADAAREGGLK F-------------------------------------------------------------YPN-AMAVARYVGISASK ARRVIDLVRGKSVEEALDILRWA---------------------------------PQQASEPVAKVIASAAAN----A- QNNE-GLDPSTLVVATIHADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVES-MKVHKGDTVLVVSGK------DK-GAK GKVIQAYPTRN--KVL--VEGVNRIKKHTA-VSSNE--RG-ASS-GGIVTQEAPIHVSNVM-VVD-SD-------GN--P --TRIGYRV---DE-E------TGKVR---VSKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YKDYVKEDVAIRRLL--ATGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESVAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKIKANIAEILKSEGYISDYR TED----A---R----VGKSLVVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARSGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTAIGYVVSDKMEKTIVVELESRKSHPLYG KIIRTTSKVKAHDEN--GDAGVGDRVSLMETRPLSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQND---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_tuberculosis_CDC1551 Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRMIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NANKSSN-K-FIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ESNR---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PLTGQYA----------------- ---AG-VNPRRYLAELRL-----DDSDAATEY-----QV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVLNLLVHKVDAENG---------------- ----------VLLIKGA-VPGRTGGLVMVRKTLKIDVKT-PAGKVD-GAIELPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGE--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VEGQN-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDALRKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVNDLALITGQKPEVRRARK SIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQAVFHEVD-----VDKI DRVRGMDINVVTS-----------------------AATDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDVT-I--- -E-G--Q-SISVKGPKGTLGLTV-AEP----IKVARNDDGA--IVV---TR-P--DDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIA ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLLK-L--HDLRPARGS-KIARTRVG-RGDGSK--GKTAGRGTKGTRARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDDLVAK-GAVRVK---------VLG--DGK-L-T-A-K-VDV- SAHKFSGSARAKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEGVARAALTRAIHKLPIKARI-IRRISRLRRHTRLRKKL---SGTAERPRLVVHRSARHIHVQLVND---L--NGTTV AAASSI-EADV-RG------VPG-DKKARSVRVGQLIAER--AKAAG-IDTVVFDRGGYTYG--GRIAALADAARENGLS F-------------------------------------------------------------YPS-AVAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASGPVAKVIASAAAN----A- QNNG-GLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVISGK------DK-GAK GKVLQAYPDRN--RVL--VEGVNRIKKHTA-ISTTQ--RG-ARS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLVIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDED--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_tuberculosis_F11 Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRMIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NANKSSN-K-FIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ESNR---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PLTGQYA----------------- ---AG-VNPRRYLAELRL-----DDSDAATEY-----QV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVLNLLVHKVDAENG---------------- ----------VLLIKGA-VPGRTGGLVMVRKTLKIDVKT-PAGKVD-GAIELPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGE--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VEGQN-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDALRKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVNDLALITGQKPEVRRARK SIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQAVFHEVD-----VDKI DRVRGMDINVVTS-----------------------AATDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDVT-I--- -E-G--Q-SISVKGPKGTLGLTV-AEP----IKVARNDDGA--IVV---TR-P--DDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIA ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLLK-L--HDLRPARGS-KIARTRVG-RGDGSK--GKTAGRGTKGTRARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDDLVAK-GAVRVK---------VLG--DGK-L-T-A-K-VDV- SAHKFSGSARAKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEGVARAALTRAIHKLPIKARI-IRRISRLRRHTRLRKKL---SGTAERPRLVVHRSARHIHVQLVND---L--NGTTV AAASSI-EADV-RG------VPG-DKKARSVRVGQLIAER--AKAAG-IDTVVFDRGGYTYG--GRIAALADAARENGLS F-------------------------------------------------------------YPS-AVAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASGPVAKVIASAAAN----A- QNNG-GLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVISGK------DK-GAK GKVLQAYPDRN--RVL--VEGVNRIKKHTA-ISTTQ--RG-ARS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLVIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDED--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_tuberculosis_H37Ra Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRMIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NANKSSN-K-FIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ESNR---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PLTGQYA----------------- ---AG-VNPRRYLAELRL-----DDSDAATEY-----QV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVLNLLVHKVDAENG---------------- ----------VLLIKGA-VPGRTGGLVMVRKTLKIDVKT-PAGKVD-GAIELPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGE--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VEGQN-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDALRKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVNDLALITGQKPEVRRARK SIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQAVFHEVD-----VDKI DRVRGMDINVVTS-----------------------AATDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDVT-I--- -E-G--Q-SISVKGPKGTLGLTV-AEP----IKVARNDDGA--IVV---TR-P--DDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIA ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLLK-L--HDLRPARGS-KIARTRVG-RGDGSK--GKTAGRGTKGTRARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDDLVAK-GAVRVK---------VLG--DGK-L-T-A-K-VDV- SAHKFSGSARAKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEGVARAALTRAIHKLPIKARI-IRRISRLRRHTRLRKKL---SGTAERPRLVVHRSARHIHVQLVND---L--NGTTV AAASSI-EADV-RG------VPG-DKKARSVRVGQLIAER--AKAAG-IDTVVFDRGGYTYG--GRIAALADAARENGLS F-------------------------------------------------------------YPS-AVAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASGPVAKVIASAAAN----A- QNNG-GLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVISGK------DK-GAK GKVLQAYPDRN--RVL--VEGVNRIKKHTA-ISTTQ--RG-ARS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLVIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDED--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_tuberculosis_H37Rv Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRMIDFR-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NANKSSN-K-FIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ESNR---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PLTGQYA----------------- ---AG-VNPRRYLAELRL-----DDSDAATEY-----QV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVLNLLVHKVDAENG---------------- ----------VLLIKGA-VPGRTGGLVMVRKTLKIDVKT-PAGKVD-GAIELPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGE--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAITEL--VEGQN-------- --PSTKLVV--IGRSD--E---AGAKSVRNLPGVH-I---------------LAPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDALRKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVNDLALITGQKPEVRRARK SIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQAVFHEVD-----VDKI DRVRGMDINVVTS-----------------------AATDDEGRALLRALGFPFMSRIG-K--QPIPVPAGVDVT-I--- -E-G--Q-SISVKGPKGTLGLTV-AEP----IKVARNDDGA--IVV---TR-P--DDERRNR-SLHGLSRTLVSNLVTGV TQGYTTKMEIFGVGY--RVQLKG-SN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIA ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKIISLAPEVLLK-L--HDLRPARGS-KIARTRVG-RGDGSK--GKTAGRGTKGTRARKQ---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDDLVAK-GAVRVK---------VLG--DGK-L-T-A-K-VDV- SAHKFSGSARAKITAAGGSA-K---QHH--PRQ---RGIA-SGGTTVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEGVARAALTRAIHKLPIKARI-IRRISRLRRHTRLRKKL---SGTAERPRLVVHRSARHIHVQLVND---L--NGTTV AAASSI-EADV-RG------VPG-DKKARSVRVGQLIAER--AKAAG-IDTVVFDRGGYTYG--GRIAALADAARENGLS F-------------------------------------------------------------YPS-AVAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASGPVAKVIASAAAN----A- QNNG-GLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVES-MKVHKGDTVLVISGK------DK-GAK GKVLQAYPDRN--RVL--VEGVNRIKKHTA-ISTTQ--RG-ARS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKLKANIAQILKNEGYISDFR TED----A---R----VGKSLVIQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRMRHPLYG KIIRTTKKVKAHDED--SVAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDE-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_ulcerans_Agy99 Concatenation of 2 sequences MAIRKYKPTTPGRRGASVSDFAE-ITRS------------TP-EKSLVRPLHGHGGRNAHGRITTRH-KGGGHKRA---- YRVIDFG-RN-DK-DGVNAKVAHIEYDPNRTARIALLHYL-DGEKRYIIAPNGLSQGDVVESGA-N-AD-IKPGNNLPLR NIPAGTLVHAVELRPGGGAKLARSAGSSIQLLGK--EASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-SVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-NPNKASN-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PVTGQYA----------------- ---AG-VNPRRHLAELRL-----DDAEAVTEY-----EV---GQ-ELTA--E-I-FADGSYVDVTGTSKGKGFAGTMKRH GFSG-QGASHGAQAVHRR-PGSIGGC-ATPA-RVFKGTRMAGRMGNDRVTVQNLLVHKVDAEQS---------------- ----------VLLIKGA-VPGRTGGLVTVRKDLEIQVKA-PDGKVD-GSVVLPAELF----DV-PA-NIALMHQVVTAQR AAARQGTHSTKTRGD--------VS-GGGRKPY---------RQKGTGRAR--------QGS---TR-TP----QF---- TGGGVVHGPK-P-RDYSQRTPKKMIAAALRGALSDRARNG----------------R-IHAVTEL--VAGQT-------- --PSTKLVV--IGRDD--Q---TGVKSVRNLPGVH-I---------------LSPDQLNTYDVLRADD----VVFSVEAL NAYIPRLKERYRSEI----RDVLHKQFGYGNVMQIPTVTKVVVNMGVG-EAARDAKLINGAVSDLALITGQRPEIRKARK SIAQFKLREGMPVGVRATLRGDRMWEFLDRLTSIALPRIRDFRGLSP-KQFDGVGNYTFGLAEQPVFHEID-----VDKI DRVRGMDINVVTS-----------------------ATTDEEGRALLRALGFPFMSRIG-K--QPVPVPTGVDVM-I--- -E-G--Q-KVSVKGPKGALDLTV-AEP----ITVSRNDDGA--IVI---SR-P--NDERRNR-SLHGLSRTLVSNLVTGV TEGYTTKMEIHGVGY--RVQLKG-AN--LEFA--LGYSHPVVIEA-P-E-GITFAVQ--A-PTKFTVSG-IDKQKVGQIS ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDIIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIK-PDND-PRGTRIF GPVGRELR-EKRFMKLISLAPEVLIK-L--HDLRPAPGS-KTPRTRVG-RGEGSK--GKTAGRGTKGTKARKQ---V--- -PTTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDELVAK-GAVRVK---------VLG--DGK-L-T-V-K-VDI- TAHKFSGSAREQITAAGGSV-K---QHH--PRQ---RGIA-SGGTSVNFG----------DYGIQAL--EHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PNEAIARAALTRAIHKLPIKARI-IRRVSRLRRHARLRKRI---AGTQQRPRLVVHRSARHIHVQLVND---A--NGTTV AAASSI-ETDV-RG------LDG-DKKARSVRVGQLIAER--AKAAD-IDTVVFDRGGYTYG--GRIAALADAARENGLK F-------------------------------------------------------------FPS-ATAKARFVRVSPRK ARRVIDLVRGRSVSDALDILRWA---------------------------------PQAASEPVAKVIASAAAN----A- QNNN-GLDPATLIVATVYADEGPTAKRIRPRAQGRAFRIRKRTSHITVVVES-MKVHKGDTVLVVSGK------DK-GAK GKVLQAYPERN--RVL--VEGVNRIKKHTA-ISTNQ--RG-AKS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRV---DE-E------TGRVR---ISKRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YADYVKEDVAIRRLL--SSGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVSL-PHSKIKANIAQILKNEGYISDFH TED----A---R----VGKSLIVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLLTDRQAARQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVVRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ-RKTRIGYVVSDKMQKTIVVELEDRVRHPLYG KIIRTTKKVKVHDEH--SAAGIGDRVSLMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Mycobacterium_vanbaalenii_PYR-1 Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVSDFAE-ITRD------------HP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVNAKVAHIEYDPNRTANIALLHYL-DGEKRYIIAPQGLKQGAIVESGA-N-AD-IKPGNNLPLR NIPAGTLVHAVELRPGGGAKMARSAGASIQLLGK--EGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-KPKKASD-K-LIVRRR --------------------------------ARK---G-ILGTKLGMTQVFD-ENNK---------VVPVTVVKAGPNV VTRIR----TPE----R--DGY--SAVQLAY-------GE--IVNK----------PVTGQYA----------------- ---AG-VNPRRHLAELRL-----DDEAAAAEY-----EV---GQ-ELTA--E-I-FADGAYVDVTGTSKGKGFAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPG-RVFKGTRMSGRMGSDRVTTQNLKVHKVDAENG---------------- ----------VLLIKGA-IPGRNGGLVVVREDRKIPVRT-PAGKTD-GSIELPAELF----DV-EP-NIALMHQVVNAQL AAKRQGTHSTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGIVHGPK-P-RDYSERTPKKMIRAALRGALSDRARND----------------R-IHAITEI--VEGQT-------- --PSTKLVV--IGRAD--E---ASALSVRNLPGVH-V---------------ISPDQLNTYDVLKADD----VVFSVEAL NAYIPRLKQRYREEI----RDQLLKEFGYANVMQIPGVTKVVVNMGVG-DAARDAKLINGAVNDLALITGQKPEIRRARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLISISLPRIRDFRGLSG-KQFDGTGNYTFGLTEQSVFHEID-----VDSI DRPRGMDITVVTS-----------------------ATNDDEGRALLRALGFPFMSRIG-K--QPVTVPSGVDVT-I--- -D-G--Q-NVSVKGPKGTLTLDV-AEP----IAVTRDDDGA--IVV---TR-P--NDERRNR-SLHGLSRTLIANLVTGV TEGYTTKMEIFGVGY--RVVAKG-SN--LEFA--LGYSHPVLITA-P-E-GVTFAVE--T-PTKFSISG-IDKQKVGQIA ANIRRLR------KSDPY---KGKGIRYEGEQIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTAKERRRADGSYIKFDENAAVIIK-NDND-PRGTRIF GPVGRELR-EKKFMKIVSLAPEVLIK-L--HDLRPAPGE-KKAKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PVTF-E-GGQMPIHMRLPKLKG--FRNVNVGDIVGVDELVAK-GLVRVK---------VLG--DGK-L-S-A-K-VDV- TAHKFSGSAREAITAAGGTA-K---QHH--PKQ---RGIA-SGGTSVSFG----------DYGIQAL--GHAYVTNRQIE SARIAINRHI------KRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEL--SY-- PDEKIAREALTRAIHKLPIKARI-VRRTSRLRRHARLRKKV---SGTADRPRLVVNRSARHIHVQLVDD---L--EGVTL AAASSI-EADV-RA------HEG-DKKAASTRVGQLIAER--AKAAG-IDEVVFDRGGYTYG--GRIAALADAAREGGLK F-------------------------------------------------------------YPS-AMAKARFVRISATK ARRVIDLVRGKSVEEALDILRWA---------------------------------PQSASEPVAKVIASAAAN----A- QNNE-GLDPTSLVVATIHADEGPTAKRIRPRAQGRAYRIRKRTSHITVIVES-MKVRKGDTVLVISGK------DK-GAK GKVLVAYPDRN--KVL--VEGVNRIKKHTP-ESRTE--RG-ASS-GGIVTQEAPISVSNVM-LLD-SD-------GK--P --TRVGYRR---DD-E------TGNVR---IAKSNG---KDI--MGQKINPHGFRLG--IT-TEWKSRWYA------D-K Q--YADYIKEDVAIRKLL--ATGLE-----RAGIADVEIERTR-D-RVRVDIHTARPGIVIGRRGTEADRIRADLEKLVQ LNILEVKN---PESVAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDEVTL-PHSKIKANIAEILKKEGYISDYR TED----A---R----VGKSLVVQLKYG---PSR-------E---RSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAII STSSGLRTDRQAAREGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKTAIGYVVSDKMQKTIVVELESRKSHPLYG KIIRTTTKVKAHDEN--EDAGVGDRVSLMETRPTSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDVQNE---KNTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTE-AMVGH KLGEFAPTRTFKGHI------K--DDR----KSK------RR >ACTINO_Nocardia_farcinica_IFM_10152 Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVSDFAE-ITRS------------TP-EKSLLRPLTKSGGRNAHGRITTRH-RGGGHKRA---- YRVIDFR-R-LDK-DGIPAKVAHIEYDPNRTANIALLHYV-DGEKRYILAPKGVTQGTPIESGP-T-AD-IKPGNNLPLR NIPTGTTIHNVELRPGGGAKLARAAGMSIQLLGK--EGPYATLRMPSGEIRRVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GRR-P-TVRGVVMNPVDHPHGGGEGKT----SGGRHPVSP---WGQP--EGRTR-KPNRPSD-K-LIVRRR --------------------------------KNRPAAG-ILGTKLGMTQVFD-EKNR---------VVPVTVIKAGPNV VTQIR----TEE----R--DGY--SAVQVAF-------GA--IVNK----------PVAGQFK----------------- ---AG-VTPRRHIAEIRV--------ADASSF-----EV---GQ-EINA--D-V-FEEGSYVDVTGTSKGKGYAGTMKRH GFRG-QGASHGAQAVHRR-PGSIGGC-ATPG-RVFKGMRMAGRMGNDRVTTQNLSVHKVDAENG---------------- ----------LLLIKGA-IPGRKGGVVIVKANLVLPVKE-AGGKSN-GTVELPAEIF----DV-TA-NIALMHQVVTAQL AAARQGTHATKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- TGGGTVHGPQ-P-RDYSQRTPKKMIRAALHGALSDRARND----------------R-IHVVSEL--VAGQT-------- --PSTKLVV--VGRED--V---TAWKSVANLQNVQ-P---------------IAPDQLNTYDVLNSDD----VVFSVEAL NAFVPRLKVRYREEI----KDALAKEFNYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAVEDLALITGQKPQIRKATK SIAQFKLREGMPIGAKVTLRGDRMWEFLDRLVSIALPRIRDFRGLSP-KQFDGNGNYTFGLSEQSMFHEID-----VDKI DRPRGMDITVVTT-----------------------ATNNEEGRALLKHLGFPFMSRIG-K--KPIAVPSGVEIT-I--- -D-G--Q-HVSVKGPKGTLTHTV-AEP----ITVTRGEDGQ--LEV---TR-P--NDERRNR-SLHGLTRTLIANMIEGV TKGYEKKMEIFGVGY--RVQAKG-SN--LEFA--LGYSHPVPVEA-P-E-GITFAVE--S-PTKFSVSG-IDKQKVGQIS AVIHGLR------KPDPY---KGKGIRYAGEVVRRKVGK----------MIQQESRLRVADNTGAKEILCIRVLG-SSRR Y--AGIGDVIVATVKDAIPG-G-------NVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVLIK-ADND-PRGTRIF GPVGRELR-DKKFMKIVSLAPEVLIK-L--HHLRPAPGA-KTDKTRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -PAAF-E-GGQMPIHMRLPKLKG--FTNVNVGRIVGKAELVAA-GAVRVK---------VLG--DGE-I-G-V-A-VQV- TADKVTGSAKEKITAAGGTV-K---QHH--PSR---TGMA-KGGTSVAFG----------DYGIQAL--EPAYVTNRQIE SARIAMTRHI------RRGGKIWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVMFEM--SY-- PNEETAREALRRAMHKLPMKCRI-VRRLSKARRHFRLRKKI---AGTTERPRLVVHRSSRHLHAQLVDD---T--VGKTI AAASSI-EPDV-RA------VEG-DKTAKGKKVGELIAAR--AKAAG-VEAVVFDRGGHDYH--GRIAALADAAREGGLK F-------------------------------------------------------------NPT-ARATAKHVRVTPMK ARRVVDLVRGKRVEDALAILKFA---------------------------------PQAASEPVAKVVASAAAN----A- ENNL-GLDPATLVISTAYVDEGATLKRFQPRAQGRAFRIRKRTSHITIEVES-MKVHKGDTVLVISGK------DK-GAK GKVIQAYPKEN--RVL--VEGVNRIKKHVA-NSANQ--RG-ASS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRIGYRT---DE-N-------GRVR---ISRRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YADYVKEDVAIRKLL--ATGME-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRAELEKLVQ LNILEVKN---PESDAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRSPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDQVKA-PHSKLKANIAEILKREGYIADYR TED----A---Q----VGKTLVVDLKYG---PSR-------E---RSLAGVRRVSKPGLRVYAKSTNLPKVLGGLGVAII STSQGLLTDKQAAKQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRIGYVVSDKMNKTIVVELEDRVKHPLYG KIIRTTSKVKAHDEN--EIAGVGDRVQLMETRPLSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLQAKVDVQNE---KGTKQ----VIKTWSRRSTITPDFIGHTFAVHDGRKHVPVFVSE-NMVGH KLGEFAPTRTFKSHV------K--EDR----KSK------RR >ACTINO_Nocardioides_sp_JS614 Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVADFVE-ITRT------------TP-EKSLTRPLPKKGGRNNQGRITTRH-QGGGHKRA---- YRLIDFR-RY-DK-DGVPAKVAHIEYDPNRTARIALLHYV-DGEKRYIIAPKDLTQGTRVESGP-N-AD-IKPGNNLPLR NIPVGTTIHCVELRPGGGAKIARSAGNSAQLVAR--EGSRATLRMPSGEMRFVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPEG--RTR-K-RKASD-S-QIIRRR --------------------------------NMK---G-LLGTKLGMTQVWD-ENNR---------VVPVTVIAAGTNV VTQVR----TPA----T--DGY--NAIQVGY-------GE--IVTK----------PQAGHFK----------------- ---AG-TTPRRHLVEIRT--------ALAADY-----TV---GQ-ELAV--D-T-FAAGEEIDVTGTSKGKGFAGTMKRH GFAG-VSASHGAHRNHRK-PGSIGAC-ATPG-RVFKGVRMAGRMGTDTVTTQNVTVHAVDTAKG---------------- ----------LILLKGA-VPGPKGGLVVLRAKKAAPAKK-AAAPKA-AKVDFPAEIF----DV-EL-NVPLIHQVVVAQQ AAARQGTHATKTRGE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---TR-AP----QF---- AGGGTVHGPQ-P-RSYDQRTPKKMKVAALRGALSDRARND----------------R-IHVVESL---ITAE-A------ --PSTRLVV--LERTD--T---VTWLSLRNAPEVH-I---------------VAVDQLNTYDVLASDD----VVFTQGAY DAFVPRLKTRYREEI----VPALRSEFDIKNAMQVPGLTKIVVNMGVG-EAARDSKLIEGAVKDLTAITGQKPLVTKARK SIAQFKLREGMPIGAHATLRGDRMWEFLDRLLSLALPRIRDFRGLNP-DQFDGRGNYTFGLTEQVMFHEID-----QDRI DRSRGMDITVVTT-----------------------ATNDEQGRALLKQLGFPFMSRIG-K--LPVAVPSGVDVA-I--- -D-G--A-RVTVKGPKGTLSHTV-AAP----ITVEKGD-GV--LDV---KR-P--DDERESK-ALHGLTRTLVNNMVVGV TEGYEKKLEIVGVGY--RVLSKGPTQ--LEFQ--LGYSHPITFNA-P-E-GITFAVE--G-PTRLGVQG-IDKQLVGEVA ANIRKLR------KPEPY---KGKGVRYAGEHIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVVVRTVKERRRPDGSYIRFDENAAVILK-NDGE-PRGTRIF GPVGRELR-EKKFMKIISLAPEVLLK-L--HNLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---V--- -PAAF-E-GGQMPIHMRLPKLKG--FKNVNLDRIVGVEDLVAK-GAVRVK---------VLG--QGE-I-S-V-A-VQV- SANAFSATASEKIEAAGGTT-K---QHH--PTR---RGAA-KGGTRLAFG----------DFGIQAV--EAHYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRVMFEL--SG-- VDETVAREAMRRAMHKLPMKCRF-IRTKSRLRRQVRGRKRV---SGTPERPRLVVTRSSKHISVQVVDD---L--VGKTL ASASTM-EADL-RG------FSG-DKTAKAKKVGELVAER--AKSAG-VEGVVFDRAGNKYH--GRVAALAEGAREGGLT F-------------------------------------------------------------QPG-AFASARYARITPMK ARRVVDMVRGLPVDEALSLLQFA---------------------------------PQSASETVYKVLESAVAN----A- ELTE-GLERGDLVVSVAQVDEGPTMKRWRPRAQGRATRINKRTSHITLVVQPSVSIKKGDTVKVIAGK------DK-GAE GRVIQVLREEQ--RVI--VEGVNRVKRHTKVVNQGG--RA-GTT-GGIITAEAPIHVSNVM-LVEGGG-----------V --TRIGFRR---DE--VTKRRPDGSVR---ISRKTG---KEI--MGQKINPNGFRLG--IS-TDHKSRWYA------D-K L--YKSYVGEDVAIRKLL--SKGME-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---PEVDAQLVAQGVAEQLSGRVQFRRAMRKAMQTSMRS-GAKGIRIQCSGRLNGAEMSRTEFYREGRVPL- -HTLRADIDYGFYEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANQAYHDAVSM-PYSKLKQGVADILKQEGYITSYD VTE----P---A-EGEVGKTLTITLKYG---RNR-------E---RSIAGVRRISKPGLRVYAKHTGLPKVLGGLGVAII STSQGLLTDRQANQKGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDTSARKIVDTVTRTGAKVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVVSDKMDKTVVVSVEDRVKHALYG KVMRRTSKLKAHDEQ--NECGIGDRVLLMETRPLSATKRWRVVEILEKA------------------------------- -MPRSL-KKGPFVDD-HLQKKVDAENA---KGSHN----VIKTWSRRSMIVPDMIGHTIAVHDGRKHVPVFVTD-SMVGH KLGEFAPTRTYRGHV------K--EDR----KGR------RR >ACTINO_Propionibacterium_acnes_KPA171202 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVSDFVE-LTRS------------TP-EKSLLVAKPKTGGRNNTGRITTRH-IGGGHKQA---- YRIIDFK-RY-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPDGVGQGTVVVSGP-E-AD-IKPGNNLPLR NIPVGTTVHAVELRPGGGAKMGRSAGASVQLVAR--EGKYATVRLPSGEMRMVDIRCRATIGEVGNAEQININWGKAGRN -RWK-----GIR-P-TVRGVVMNPIDHPHGGGEGRT-S--GGRH-PVSP---WGKPEG--RTR-NKKKASS-R-LIVRRR --------------------------------TVK---G-VLGTKLGMTQLWD-EHNR---------LVPVTVIQAGPCV VTQVR----TPE----T--DGY--SAVQLGY-------GA--VVTK----------PEAGHFK----------------- ---AG-VTPRRHLVELRT--------ADASEY-----TL---GQ-EIAA--D-V-FSESDFVDVTGTSKGKGTAGVMKRH GFGG-LRATHGVHRKHRS-PGSIGGC-STPG-KVIKGLRMAGRMGVERVTVQNLQVHSVDAERG---------------- ----------IMLVRGA-VPGPKGSLLVVRETKTIDVLD-VKGKKA-GSAELPGDLF----DV-NT-NIPLIHQVVVAQL AAARQGTHATKTRGQ--------VS-GGGKKPW---------RQKGTGRAR--------QGS---TR-AP----QW---- VGGGTVHGPQ-P-RSYAQRTPKKMVGAALRGALSDMARDN----------------R-IFVVTSL--V-DGD-K------ --PSTKLVV--LDRSD--E---IDWLSVRNLSEVH-V---------------LAADQLNTYDVVNART----IVFSQAGL DAFVPRLKKQYREQI----RAAMQEEFGYRNPMLIPGLEKIVVNMGVG-DAAHDSKVMDGAIRDITAITGQKPQVTKARK SIAQFKLREGQPIGCHVTLRGDRMWEFADRLLTLALPRIRDFRGLNS-NQFDGKGNYTFGLSEQVMFLEID-----QDKI VRIRGMDITFVTT-----------------------AQTNEEGKALLKHLGFPFMSRIG-R--LPIAVPSGVEVK-L--- -D-G--Q-YVEVKGPKGTLNFTV-REP----ITVSKNDEGA--ILV---ER-P--DDERENR-SLHGLTRTLINNMVIGV TEGYEKKLEIQGVGY--RVLSKGPKQ--LEFN--LGFSHPVIVDA-P-E-GITFAVE--N-PTKFSVQG-IDKQVVGETA ANIRKIR------KPEPY---KGKGVRYEGENVRRKVGK----------MIQQETRLKVADNTGAKELLCIRVLG-SKRR Y--AYLGDTIVCTVKDAIPG-G-------NVKKGEVVKAVVVRTVKSHRRPDGSYIKFDENAAVLLK-GDGE-PRGTRIF GPIARELR-EKKFMRIVSLAPEVIIE-L--HDLKPAPGA-HKAKTRVG-RGEGSK--GKTAGRGTKGTGARKN---V--- -PEFF-A-GGQMPIHMQAPKLGG--FHNVNLDKVITVDDLVSV-GAVRVK---------VLG--TGE-L-T-V-K-VDL- VVDAWSKSAQEKIEKAGGSV-K---QHH--PKR---TGAA-KGGTQLAFG----------DYGIQAT--EGGYLTNRQIE AARIAMTRYI------KRGGKVWINVYPDRPMTKHPAESRMGSGK---------GTPEWWIANIKP-GRVLFEL--SG-- VPEDVAREAMRLAIHKLPMKARF-IRAKARARRQARGRKKI---FGTVERPRMVVTRSSKHVFVQVIDD---V--AGNTL VSASTM-EAEL-RE------MSG-DKTAKAARVGTIIGER--AKAAG-ITKVVFDKAGNQYH--GRIAALADAAREAGLD F-------------------------------------------------------------RPG-SYAIARHVRMSASK CRRVINLVRGMDAVDAVTMLKFQ---------------------------------PQAAAEPIRKVIASAMAN----A- EQTE-GLRADDLYISQAFVDEGITMRRIRPRAKGSASRILKRSAHITVVVEPSLKIKKGDRVKVIAGN------DK-GAI GEVLSVDPARE--RVV--VEGVNIRKHHRR--DMPT-PQG-GTTKGGIISSEAPIHVSNVQ-LVTKID-------GK--D VVTRVGYRR--VDV---TKRRPDGSVR---YLKKEE---AK---MGQKINPHGFRLG--VT-TDHKTRWYA------E-K Q--YAELVGEDVKIREWL--HKNLE-----RAGLSSIEIERRS-E-RVTIFLYAARPGIVIGRNGAEAERVRGELEKLIQ LNILEVKS---PETDAQLVAQGIAEQLAARVAFRRAMRKAQQSAMNA-GALGIRIKCSGRLGGAEMSRSEGYREGRVPL- -HTLRADIDYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANQAYHDQTSM-PHSKIKAGIAGILKSEGYIADYK VNE----P---K-EGEVGKTLTLTLKYG---ENR-------E---RSIAGVRRISKPGLRVYAKSTALPKVLGGLGIAII STSQGLLTDKQAHEKSVGGEVLAYVWMAGQKIRIRLRAYDHEVIDSSARKIVDTVTRTGAKVAGPVPLPTEKNVFCVIRS PHKYKDSR-EHFEMRTHKRLIDILEPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVVSDKMNKTITVMVEDRVKHPLYG KVMTKSVRLKAHDEN--NEAGMGDRVRIMETRPLSATKRWRLVEIIEKA------------------------------- -MPRSL-KKGPFVDE-HLAKKVTAQNE---AGTHN----VIKTWSRRSMVTPDMIGHTIGVHDGRKHVPVFVTE-SMVGH KLGEFAPTRTFKGHV------K--DDK----KAR------RR >ACTINO_Renibacterium_salmoninarum_ATCC_33209 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFAE-ITRS------------TP-EKSLVRPLPKSGGRNNSGKITTRH-KGGGHKRQ---- YRLIDFR-RH-DK-DGVNAKVAEIEYDPNRTARIALLHYV-DGTKRYIIAPNKLKQGDFVEAGP-S-AD-IKPGNNLPLR NIPVGTTIHAVELRPGGGAKMARSAGASVQLVAK--EGRFAQLRLPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVSMNPVDHPHGGGEGKT-S--GGRH-PVNP---NGKREG--RTR-RPNKESD-K-LIVRRR --------------------------------NVK---G-ILGTKLGMTQVWD-ENNK---------LVPVTVVQADSNV VTQLR----DAA----K--DGY--TAVQIGY-------GQ--IVTK----------PLAGHFK----------------- ---AG-VTPRRHVVELRT--------NDSDAY-----SL---GQ-ELSV--E-I-FEAGQKVDVVGTSKGKGFAGVMKRH GFHG-VGASHGAHKNHRK-PGSIGGA-STPS-RVFKGLKMAGRMGGERHTTLNLTVHAIDAEKS---------------- ----------LLLIKGA-IPGARGRVVLVR-----------MATKT-VKVELPAEIF----DV-QT-NVPLLHQVVVAQL AAARQGTQKTKTRAE--------VS-GAGRKPF---------KQKGTGRAR--------QGS---IR-AP----HM---- TGGGVVHGPT-P-RDYSQRTPKKMKAAALRGALSDRARNE----------------R-IHVVAEL--VAGTK-------- --PSAKLVV--IERAN--D---VAALSVRNLADIH-V---------------LYVDQLNTYDVLISDD----VVFTKTAY EAFVPRLKTRYADEI----KKTLQDDFSYVNVNQVPRLVKVVVNMGVG-EAARDSKVIDGAVRDLTLITGQKPMVTKARK SIAQFKLREGMPIGAHTTLRGDRMWEFVDRLVTLALPRIRDFRGLSG-KQFDGNGNYTFGLTEQVMFHEID-----QDAI DKIRGMDITVVTT-----------------------AKTDDEGRALLKALGFPFMSRIG-R--LPISVPAGVEVK-V--- -D-G--A-LVSVKGPKGQLTLTV-SNP----IEVALEE-ST--LTV---SR-P--NDERASR-SLHGLTRTLIANLITGV TEGYEKKLEIVGTGY--RVLAKG-SD--LEFA--LGYSHPVAVKA-P-E-GITLTVE--G-PTKLSVAG-IDKQQVGEVA ANIRKLR------KPDPY---KGKGIRYADEVIRRKVGK----------MIQQESRLKVADNTGAKEILAIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTKKERRRADGSYIKFDENAAVILK-NDGD-PRGTRIF GPVGRELR-DKKFMKIISLAPEVLLK-V--HHLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---I--- -KAGF-A-GGQLPLHMRLPKLRG--FKNVNLDKLITVENLIAN-GAVSVK---------VLG--TGE-L-T-V-K-VQV- TVNAYSASAIEKIVAAGGTA-K---QHH--PGR---SGQA-TGGTKVSFG----------EYGIQAL--TPAYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRVLFEL--SG-- VNEEVAREALRLAIHKLPLKARI-VRSAARGRRHLRVRKRI---TGTEARPRLVVTRSARHIFVQVVDD---S--KGVTV ASASTL-EADL-RTFE------G-DKTAKAKRVGELVADR--AKKAG-VETVVFDRGGNKYH--GRIAAVADGAREGGLS L--------------------------------------------------------------ME-AKAIARHIRVTPMK ARRVVNLIRGKQANEALAILKFA---------------------------------PQAASEPVFKVLQSAVANARVLA- DRDSVAFDEGDLFISEAFVDEGPTMKRFQPRAQGRAYRIRKRTSHITVVVATKINIKKGDLVQVITGAKAERGGDR-GKQ GKVLRVFTESN--RVL--VEGINRVTKHTK-VGQSQ--RG-SKT-GGIEIVEAPIHISNVA-LVDPST-------KK--T --TRVGYRL---ET--VER---DGRVR---FAKSSG---KDL--MGQKVNPHGFRLG--IT-TNHVSHWFA-DSNKAG-Q R--YKDFVREDIKIRQLM--STGME-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---PEMEAQLVAQGIAEQLSSRVAFRRAMKKAMQSAQRA-GAKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRAQIDYGFFEAKTTFGRIGVKVWIYMTMTDPVADMLTRLRNANSAHHDSVKM-PFSKLKGHVADILKAEGYIASWK VED----A---E----VGKSLTIDLKFG---PNR-------E---RSIAGIRRISKPGLRVYAKSTNLPKVLGGLGVAIL STSSGLLTDRQAAKKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDVSARKIVETVTRAGATVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKLRKTRRGYVVSDKMQKTIVVQVEDRVKHALYG KVLRRTSKVKAHDEE--NSAGIGDLVLISETRPLSATKRWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDQ-HLFVKVANENE---KGTKN----VIKTWSRRSMIIPDMLGHTIAVHDGRKHIPVFVTE-SMVGH KLGEFALTRTFRGHV------K--DDR----KGK------RR >ACTINO_Rhodococcus_sp_RHA1 Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVSDFAE-ITRS------------TP-EKSLVRPLHGRGGRNAHGRITTRH-KGGGHKRA---- YRLIDFR-RN-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPKGLAQGAPVESGA-G-AD-IKPGNNLPLR NIPTGTTIHAVELRPGGGAKMARSAGSSIQLLGK--EGTYATLRMPSGEIRRVDVRCRASIGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGKPEG--RTR-K-NKASD-K-LIVRRR --------------------------------KIK---G-ILGTKLGMTQVFD-ENNR---------VVPVTVVKAGPNV VTQIR----TEE----R--DGY--SAVQLAF-------GA--IVNK----------PTSGQFK----------------- ---AG-VTPRRHVVELRV--------ADTSEY-----EV---GQ-ELTA--E-V-FEDGAYVDVTGTSKGKGFAGTMKRH GFAG-QGASHGAQAVHRR-PGSIGGC-ATPG-RVFKGMRMSGRMGSDRITTQNLSVHKVDAENG---------------- ----------LLLIKGA-IPGRKGGLVIVKTKLTLDVKV-AGGKTN-GTVDLPAEIF----DA-PA-NIALLHQVVVAQL AAARQGTHATKTRGE--------VR-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGTVHGPQ-P-RDYSQRTPKKMKAAALRGALSDRARNE----------------R-IHVITEL--VAGQT-------- --PSTKLLV--VGRED--I---AAWKSVQNLDGVH-P---------------IAPDQLNTYDVLNSDD----VVFSVEAL NSFIPRLKTRYREEI----KAALNTEFDYANVMQIPGVVKVVVNMGVG-DAARDAKLINGAVNDLALITGQKPEIRKARK SIAQFKLREGMPIGARVTLRGDRMWEFLDRLVSVALPRIRDFRGLSG-NQFDGNGNYTFGLNEQSMFHEID-----VDKI DRPRGMDITVVTT-----------------------ATNNEEGRALLKHLGFPFMSRIG-K--IPVTVPGGVDVS-I--- -D-G--Q-DVTVKGPKGSLALTI-SEP----IAIAKNDDGT--LSV---TR-P--DDERRSR-ALHGLSRTLVQNLITGV TDGYTTKMEIHGVGY--RVALKG-KD--LEFA--LGYSHPVPIEA-P-E-GITFAVE--S-PTKFSVSG-IDKQKVGQIS ANIRRLR------RPDPY---KGKGVRYEGEQIRRKVGK----------MIQQESRLRVADNTGAKEILCIRVLG-SSRR Y--AGIGDIIVATVKDAIPG-G-------NIKKGEVVKAVIVRTTKERRRPDGSYIKFDENAAVLIK-PDND-PRGTRIF GPVGRELR-EKKFMKIVSLAPEVLIK-L--HHLRPAPGA-KSDKIRVG-RGEGGKR-GKTAGRGTKGTKARKN---V--- -PAAF-E-GGQMPLHMRLPKLKG--FTNVNVGDIVTVEDLVAK-GAVRVK---------VLG--DGD-L-T-V-A-VQV- TVDKFTGSAKEKIAAAGGTA-K---QHH--PSR---SGAA-KGGTQVTFG----------DYGIQAL--EPAYITNRQIE SARIAMTRHI------KRGGKIWINIFPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRVMFEM--SY-- PNEEIAREALRRAMHKLPCKCRI-VRRLSKVRRHFRLRKKV---SGTPERPRLVVNRSARHIHVQLVDD---L--AGHTL AAASTT-EADV-RA------ADG-DKKALSAKVGQLIAER--AKAAG-VEAVVFDHGGHGYH--GRIAALADAAREGGLK F-------------------------------------------------------------NPT-AKAVARHVRVTPMK ARRVVDLVRGRSVEDALNILKFA---------------------------------PQAASEPVAKVIASAAAN----A- ENNL-DLDPSTLVVATAFVDEGATLKRFQPRAQGRAFRIRKRTSHITVIVES-MKVHKGDTVLVIAGK------DK-GAK GKVIQAYPATN--KVL--VEGVNRIKKHTA-VSANE--RG-ASS-GGIVTQEAPIHVSNVA-VVD-SD-------GN--P --TRVGYRT---DE-E------SGRVR---ISRKNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YAEYVKEDVAIRKLL--ATGME-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRSELEKLVQ LNILEVKN---AEAEAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEAKTTFGRIGVKVWIYMTMTDPIADFLTRLRNANTAYHDEVKL-PHSKIKANIAEILKREGYIADYR TED----A---E----VGKTLIVDLKYG---PSR-------E---RSLAGVRRVSKPGLRVYAKSTNLPKVLGGLGVAII STSTGLLTDRQAANQGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVRTGYVVSDKMEKTIVVELEDRVKHPLYG KIIRRTSKVKAHDEN--GVAGIGDRVQLMETRPLSATKHWRLVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLLAKVDVQNE---KGTKQ----VIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVSD-SMVGH KLGEFAPTRTFKGHI------K--DDR----KAK------RR >ACTINO_Rubrobacter_xylanophilus_DSM_9941 Concatenation of 2 sequences MPARRYKPTSPGRRNSSVLTRDS-VTKE------------KP-EKSLLAKLHKTGGRNVHGRITTRH-KGGGHKRR---- YRIIDFK-RN--K-DGVPATVAAIEYDPNRSANIALLHYH-DGEKRYILAPRNLTVGSVVMSGP-E-AE-VDVGNALPLA NIPVGTTVHAVELEPGRGAQLARSAGTSAQIIAR--EGNLVTLRLPSGERRRVRAECRATVGVVGNQSHQNVRWGKAGRK -RHL-----GIR-P-TVRGTVMNPVDHPHGGGEGKS-T--PGRA-PVTP---WGKITQGKPTR-KKRKRSD-A-MIVARR --------------------------------MAT---A-VFARKKYMTQAFQ-DDGT---------AVGVTVLEVEPNV VTAVK----TAE----K--DGY--EAVQVGF-------GA--VVNR----------PHAGVFK----------------- ---LD-IPPRRYLRELRG---------VSGEV----------GQ-TIGA--D-A-FEAGDRVHVSARSKGRGFQGTVKRH GFGR-GPVTHGS-HNIRQ-PGSVGAS-ADPS-RIFKGQRMPGHMGDRSVTVRNLEVVRVDAERN---------------- ----------EIWVRGG-VPGGRNAIVKVR-MAQAQVFD-ARTGRR-SEMELKGPRF----ET-EP-KQHVIHRAVVAEL EARRRWTASTRERSE--------VA-GSGAKLY---------RQKGTGRAR--------AGD---IK-SP----LR---- HGGGTWGGPK-P-KGYGKKINRKEARAAFDGALSAKAAEG----------------R-LYVLDAL----DFE-R------ --PSTKLLV--LGEER------EAALSFRNLPEVT-V---------------VGPRGYGVYELLRARE----VVFSRAAY GRLTARLKDRYRQEV----APALKERFGIDNPMRVPTLEKIVVNMGVG-EAAQDSRKLDGAMEDLARITGQKPQVRRARK SIAGFKIREGMPVGARVTLRGERMWEFLDRLISVALPRVRDFRGVSP-DSFDGRGNYALGVREQLIFPEIS-----YDAV DSVRGLDIAIVTT-----------------------AETDEEARELLRLLGMPFMSRIG-R--APVEVPGGVSVE-I--- ---S-AR-SVKVRGPKGELTVPV-GRG----VSVREED-GK--LLV---ER-S--SDAPQHR-AMHGLTRSLLHNAVVGV TDGFAKTLQISGVGY--RAQLQG-QN--VVLQ--VGYSHPVTVQP-R-E-GIQLEVP--N-PTTIVVRG-IDKQQVGQMA AEIRRVR------PPEPY---KGKGIRYEGEQVRRKVGK----------MIQQETRLKVADNSGARSLLCIRVLG-SKRR S--AGIGDVIVASVKEATPG-G-------AVKKGDVVRAVVVRTKKETRREDGSYIRFGENAGVLIN-SDGS-PRGTRIF GPVARELR-EKGYTRIISLAPEVLMR-L--NELSPPPGS-RRARKRVG-RGEGSGY-GKTSGRGQKGAKARSGTK-A--- -YTTY-E-GGQMPLQRRLPRLKGEAGRHVNVGELIGLDELRAA-GLIRVK---------ILG--DGE-I-D-R-P-VTV- RAHAFSRAAREKIEAAGGRA-K---PQR--GRM---KGRA-KGGTEVQFG----------EYGLQAL--EPAWITNRQIE AARIAMTRKI------RRGGKVWINIFPHKPVTKKPAETRMGSGK---------GSPEEYVAVVKP-GRVMFEM--SG-- VGEELAREAMRLAAQKLPIKTRF-LKRAQRERRHRRVRRKI---FGTPERPRLSVYRSNVHTYAQLIDD---I--AGHTL AAADSR-EVGE-AE----------SRVEAARKVGELIASR--AREAG-IERAVFDRGGYKYH--GRVAALAEGARAGGLK F-----------------------------------------------------------------MRAVAKYVRISPRK ARLVADQIRGKSYPEAASILRFT---------------------------------NKRAARILGDVLKSAAAN----A- ENNH-DADPELLFVEEVRVDEGPTIKRYRPRALGRATMIRKRTSHITLRLGAAAKIKRGDTVVVISGR------EK-GKR GEVERVLPREN--RVV--VKGVNTRTRHAR----PS--QQ--NP-DGLYRFDAPIHISNVM-LVDPNT-------GE--P --TRVGYRF---TE--------SGKVR---VAKRSG---KDI--MGQKVHPEGFRLG--VR-RDFKSQWYS------D-R D--FAELLGEDLKIREHI--ERKLA-----RAGIAEIEIKKAAEQGEVVVDIHTARPGIVIGKGGSEVDALRRDLERLVQ VNVREVSR---PELNAKLVAESIAEQLEGRAAFRRTMKRALTSAMRS-GAVGARIQCSGRLGGIEMSRSETVSEGKVPL- -HTLDADIDYGFKEANTQMGQIGVKVWINMAVNDPIADMLTRIRNAVMAKHERVEI-PHSKMKVEIARILKEEGYVRDYA VRG----S---G----PQQRIVIELKYG---PDG-------E---RAITGLRRMSRPGRRVYRKQKDIPRVLDGLGVAIL STSQGILTDHEARRKGVGGEVLCFVYMAVSKIRIKLKAYDHEVIDKTARSIVETAERTGAFVFGPVPLPTKRSRYTVIRG PFKDKDSR-EHFQLNTHKRLIDIQQPTPRTVDSLQRLDLPAGVNIEIKARKERVGLVVSDAADKTVTVSVETLKEHPMYK KRIRRSKKFLVHDER--NEARVGDTVRIIETRPLSRRKRWRLASIISRA------------------------------- -MTRSS-KKEPFVEE-KLMRRILEMNE---KNEKR----MIKTWSRASVIYPEMVGHTIAVHDGRKHVPVYITE-SMVGH RLGEFAPTRTFRSHK------K--DDR----TAR------RR >ACTINO_Saccharomonospora_viridis_P101,_DSM_43017 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFAE-LTRS------------EP-EKSLVRPLHGRGGRNSGGRITTRH-KGGGHKRA---- YRIIDFR-RN-DK-DGVPAKVAHIEYDPNRSARIALLHYA-DGEKRYIIAPDKLKQGDKVESGP-R-AD-IKPGNNLPLR NIPVGTMIHAIELRPGGGAKIARSAGVSVQLVAK--EGPYAQLRMPSGEIRNVDVRNRATVGEVGNSEHANINWGKAGRS -RWR-----GKR-P-AVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVNP---NGKPEG--RTR-R-RKPSD-K-LIVRRR ---------------------------------MK---G-ILGTKLGMTQVFD-ENNR---------VVPVTVVKAGPNV VTQVR----SKE----K--DGY--SAVQLAF-------GN--IVNK----------PQAGHFK----------------- ---AG-VTPRRYLAELRT--------SDADSY-----EV---GQ-EITA--D-V-FSDGAVVDVTGTSKGKGFAGVMKRH GFAG-QGASHGNQATHRA-PGSIGGA-ATPG-RVFKGKRMAGRAGNKRVTTQGLTIHSVRAEEG---------------- ----------LLLIKGA-VPGPKGGLVFVRMTATVELKT-PTGEAQ-GTVELPSEIF----DV-QA-NIPLMHQVVVAQM AAARQGTHDTKTRGE--------VR-GGGRKPY---------RQKGTGRAR--------QGS---IR-AP----QF---- VGGGTVHGPT-P-RDYTQRTPKKMKAAALRGALSDRARAG----------------Q-VHIITEL--VTGEK-------- --PSTKLVV--LHRDD--E---LGRLSARNLPYVH-L---------------LTPDQLNTYDVLVNDD----VVFTKAAF DAFLPRLKTRYREEI----VGQLREEFGYTNPHQVPGVVKVVVNMGVG-DAARDSKLIEGAIRDLATITGQKPEVRRARK SIAQFKLRQGQPIGARVTLRGDRMWEFLDRLLTIALPRIRDFRGLSD-RQFDGNGNYTFGLNEQSMFHEIS-----PDSI DRPRGMDVTVVTS-----------------------ANSDEEGRALLRKLGFPFMSRIG-K--LPINVPSGVDVT-I--- -D-G--Q-RVTVKGPKGTLEHTV-PEP----ITVERDDNGA--LLV---KR-P--DDERETR-ALHGLTRTLVNNLVVGV TQGYEKRMEIHGVGY--RVQAKG-SD--LEFA--LGYSHPVLVKA-P-E-GITFKVE--S-PTKFSVSG-IDKQQVGQTA AVIRRLR------RPDPY---KGKGVLYEGERIRRKVGK----------MIQQESRLRVADNTGAKEILTIRVLG-SGRR Y--AGIGDIIVATVKDAIPG-A-------NVKRGDIVRAVIVRTAKEKRRPDGSYIRFDENAAVLIK-NDNE-PRGTRIF GPVGRELR-DRKFMKIISLAPEVLIK-I--HHLKPAPGA-KREKIRVG-RGEASKG-GKTAGRGTKGTKARKN---V--- -PVGF-E-GGQMPIHMRLPKLRG--FNNVNVGDLIGKDELVAR-GIVHVK---------VLG--DGD-V-SGV-K-FEL- TVDAFSKSAKEKIEAAGGSI-K---QHA--PRR---SGAA-KGGTKVHFG----------DFGIQAL--EHGYVTNRQIE SARIAMTRHI------KRGGKIWINVFPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRVVFEM--SF-- PNEAVAREAMRRAIHKLPMKCRI-VRRAGRVRRHNRLRKKI---SGTPQRPRMSVKRSSRHIFVQLIDD---V--AGHTL ASASSL-EADV-QA------VEG-DKKAKAAKVGELVAAR--AKEAG-IAKVVFDRGGNAYH--GRIAALADAAREGGLE F-------------------------------------------------------------LPT-AVARARFVRDSPTK VRRVIELIKGRNANEALTVLRFA---------------------------------PQAASDQVAKVLASAMAN----A- ENNL-DLDPDTLWVKNAYADEGPTLKRIRPRAQGRAYRIRKRTSHITVVVES-MKVKKGDTVLVIAGK------DK-GAK GKVIKAYPARQ--RVL--VEGVNRIKKHTR-ITQTQ--RG-AQS-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRVGYRI---GE-D-------GKVR---ISRRTG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YSEYVAEDVKIRKLL--STGME-----RAGISKVEIERTR-E-RVRVDIHTARPGIVIGRRGAEADRIRGALEKLVQ LNILEVKN---PEADAQLVAQGIAEQLSNRVAFRRAMRKAIQTSMRSPQVKGIRVQCSGRLGGAEMSRSEHYRDGRVPL- -HTLRADIDYGFFEARTTFGRIGVKVWIYMTMTDPIADFLTRLRNANSAYHDTVVL-PHSKIKANIAEILKREGYIADYR VEP----G---E----KHKNLVVELKYG---PNR-------E---RSIAGLRRVSKPGLRVYAKSTNLPSVLGGLGVAII STSSGLQTDRQCKRNGVGGEVLAYVWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGASVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ-RKVREGLVVSDKMDKTIVVELEDRKKHPLYG KVMRTTKKVKAHDEQ--NTAGVGDRVLLMETRPLSATKRWRLVEIREKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDALNE---SGKKT----VIKTWSRRSTIIPDMLGHTIAVHDGRKHVPVFITE-AMVGH KLGEFAPTRTFKGHV------K--EDR----KSR------RR >ACTINO_Saccharopolyspora_erythraea_NRRL_2338 Concatenation of 2 sequences MGIRKHKPTTPGRRGSSVSDFAE-ITRS------------EP-EKSLLRPLHGRGGRNAHGKITTRH-KGGGHKRA---- YRLIDFR-RN-DK-DGVPAKVAHIEYDPNRSARIALLHYA-DGEKRYIIAPNNVRQGDRIESGA-R-AD-IKPGNNLPLR NIPTGTVVHAIELRPGGGAKIARSAGARVQLVAK--DGPYAQLRMPSGEIRNVDARCRATVGEVGNSEHANINWGKAGRM -RWK-----GKR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGRH-PVNP---KGKPEG--RTR-R-NKPSD-K-LIVRRR --------------------------------QIK---G-ILGTKLGMTQVFD-DQNR---------VVPVTVVQAGPNV VTQIR----TPE----K--DGY--SAVQLAF-------GA--IVNK----------PRTGHFK----------------- ---AG-VTPRRHVVELRT--------ADAGEY-----EV---GQ-EVTA--E-V-FEAGTVVDVVGTSKGKGFAGTMKRH GFRG-QGASHGTQAVHRK-PGSIGGC-ATPG-RVFKGMRMSGRMGSDRVTTQNLKVHRVEGESG---------------- ----------LLLIKGA-IPGPKGGLVLVKMSVTLDVRT-PDGKTD-GTVELPAEIF----DV-QA-NIALMHQVVVAQL AAGRQGTHATKTRGQ--------VS-GGGKKPY---------RQKGTGNAR--------QGS---IR-AP----QF---- TGGGTVHGPQ-P-RDYSQRTPKKMKVAALRGALSDRVRAG----------------Q-LHVVSHV--VGGEQ-------- --PSTKLVV--LNKSE--E---TSWLSLRNLQNVH-L---------------IDPSQLNTYDVLVNDD----VVFTKAAF ERFVPRLKTRYRDEI----RQALNEEFHYSNAMQVPGVVKVVVNMGVG-DAARDSKLIEGAVRDLATITGQKPEIRKARK SIAQFKLREGMPIGARVTLRGDRMWEFIDRLVTIALPRIRDFRGLSG-KQFDGKGNYTFGLNEQSMFHEID-----PDSI DRPRGMDITVVTT-----------------------ANTDEEGRVLLRRLGFPFMSRIG-K--LPITVPSGVEVT-I--- -D-G--Q-DVTVKGPKGSLVQRI-AEP----ITVEKDDDGA--ILV---KR-P--DDERNSR-SLHGLSRSLVNNMVVGV SQGYQKDLEIHGVGY--RVQQKG-SN--LEFA--LGYSHPVVVEP-P-E-GIEFATD--G-PTKLSVKG-IDKQLVGEIA ARIRKLR------RPDPY---KGKGVRYAGENIRRKVGK----------MIQQESRLRVADNSGAKEILTIRVLG-SGRR Y--AGIGDIIVATVKDAIPG-A-------NVKKGEVVKAVIVRQKKEKRRADGSYIRFDENAAVLIK-PSGE-PRGTRIF GPVGRELR-DKKYMKIISLAPEVLIK-I--HDLRPAPGS-KRDKIRVG-RGEGSK--GKTAGRGTKGTKARKN---V--- -SPRF-E-GGQMPIHMRLPKLRG--FKNVNVGKLVGIDELISA-GLANVK---------ILG--DGD-L-EGV-K-LEV- TAHAFTGSAQEKITAAGGSV-K---SHA--PKR---KGFA-KGGTRINFG----------EYGIQAI--EHGYVTNRQIE SARIAITRHV------KRGGKVWINIFPDRPLTKKPAETRQGSGK---------GSPESWVANVKP-GRVMFEL--NF-- PNEKTAIEALTRAAHKLPMKCKI-VRRTARANRHFRLRKKV---SGTPARPRLVVTRSTRHIVAQVIDD---V--AGHTL ASASTL-EADL-RS------FDG-DKKAKAAKVGELVAAR--AKEAG-IAAVVFDRGGNAYH--GRVAALADAARDGGLE F------------------------------------------------------------------MARARFVRVTPMK ARRVVELIKGRSASEALAVLQFA---------------------------------PQAASGPVSKVLASAVAN----A- ENNL-SLDPDTLWVHRAYVDEGPTLKRFRPRAQGRAYRIRKRTSHITVEVES-MKVKKGDTVVVISGK------DK-GAK GKVIQAFPQRD--KVL--VEGVNRIKKHTK-VSRTE--RG-AQS-GGIVTQEAPIHVSNVM-VVD-SD-------GQ--P --TRVGYRI---GE-D-------GKVR---ISRRNG---KDI--MGQKINPHGFRLG--IT-TDWKSRWYA------D-K Q--YSEYVAEDVKIRRRL--SRGME-----RAGISKVEIERTR-E-RVRVDIHTARPGIVIGRRGAEADRIRGSLEKLVQ LNILEVKN---AEADAQLVAQGVAEQLSNRVSFRRAMRKAIQSAMRSPQVKGIRVQCGGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNGNSAYHDEVVM-PHSKLKANIAEILKREGYVSGYR TEQ----G---E----KGQNLVVELKYG---PNR-------E---RSIAGLRRVSKPGLRVYAKSTNLPKVLGGLGIAII STSGGLLTDRQAIKQGVGGEVLAYAWMAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDILEPTPKTVDALMRIDLPASVDVNIQ-RKVREGYVVSDKMDKTIVVSLEDRKKHALYG KVMRRNTKVKAHDEA--NTAGVGDRVLLMETRPLSASKRWRLVEVVEKA------------------------------- -MPRSL-KKGPFVDD-HLLKKVDALNE---SGKKT----VIKTWSRRSTIIPDMLGHTFAVHDGRKHIPVFVNE-SMVGH KLGEFAPTRTFKGHV------K--DDR----KSR------RR >ACTINO_Salinispora_arenicola_CNS-205 Concatenation of 2 sequences MAIRKYRPTTPGRRGSSVADFAE-ITRS------------TP-EKSLLAPLPKKGGRNAHGRITTRH-QGGGHKRQ---- YRIIDFK-RV-DK-DGVPAKVAHIEYDPNRTARIALLHFL-DGEKRYIVAPKDLKQGDIVESGP-G-AD-IKPGNNLPLR NIPVGTTIHNVELRPGGGAKLARSAGVGIQLLGR--EGAYATLRMPSGEIRRVDVRCRASIGEIGNADQSNINWGKAGRM -RWK-----GKR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---QGKPEG--RTR-RKGQPSD-R-LIVRRR --------------------------------QVK---G-ILGAKLGMTQVW--DNNR---------VVPVTVVQAGPCV VSQVR----SHQ----K--DGY--AAVQLAY-------GA--IVKK----------PISGHYK----------------- ---AD-VAPRRHIVELRT--------TDAAEY-----SL---GQ-EVTV--E-Q-FPAGISVDVTGKTKGKGYAGPMKRH GFHG-LRASHGVERKHRS-PGSIGGC-ATPG-RVFKGTRMAGRMGGVRYTVQNLTVQAVDTENN---------------- ----------LLLVRGA-IPGPKGALVLVR-MTTVDVHT-VEGTTA-GSVELPADIF----DA-QA-NIALMHQVVVAQL AAARQGTHKTKTRGE--------VA-GGGKKPY---------KQKGTGRAR--------QGS---IR-AP----QF---- AGGGVVHGPV-P-RDYSQRTPKKMKAAALRGALSDRTRAG----------------K-LHVVEAF--VAGEK-------- --PSTKLVV--LSSTD--E---LNWVSLRNEPRVH-L---------------IESGQLNTYDVLVADD----VVFTREAL DEFLPRLKERYRNEI----VGQLREQYKYGNPMQVPGLVKIVVNMGVG-EAARDAKLIDGAVRDLATITGQKPQVRRATK SIAQFKLREGMPIGAKVTLRGDRMWEFLDRLLSIALPRIRDFRGLDG-RKLDGNGNYTFGLTEQSVFHEID-----QDKI DRQRGMDITVVTT-----------------------ATTDDEGRALLKFLGFPFMSRIG-R--KSIPVPAGVDVT-I--- -D-G--Q-TVKVKGPKGELSHTL-AEP----ITVERAEDGQ--LNV---AR-P--NDERKAK-ELHGLSRTLVANMIVGV TEGYRKSLEIAGTGY--RVTAKG-KD--LEFA--LGFSHPVTVVA-P-E-GITFSVE--K-PTLFHVAG-INKQLVGEVA ANIRKIR------PPEPY---KGKGVKYQGEVIRRKAGK----------MIQQESRLRVADNTGAREILCIRVLG-SGRR Y--ASIGDVIVATVKDAIPG-A-------GVKKGDVVKAVVVRTAKEKRRPDGSYIRFDENAAVIIK-DGGD-PRGTRIF GPVGRELR-DKRFMKIISLAPEVLIK-V--HHLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGSKARKN---I--- -SAAF-E-GGQMPIHMRLPKMKG--FKNVNLERLVGPAELVDA-GAVRVK---------VLG--TGD-LGG-V-A-LQV- SAHAFSASAKEKITAAGGST-K---PHH--PDR---SGAS-KGGNRVVFG----------EFGIQAL--EPAYVTNRQIE SARIAMTRHI------KRGGKVWITIFPDQALTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEM--SF-- PNEQIAREAMRRAIHKLPMKCRI-VRAVGRARRHFRVRRQV---SGTPQRPRLVVTRSLRHIVAQVVDD---T--KGHTL ASASTL-DASL-RG------VQG-DKSALAGKVGVLLAER--AKAAG-IAKVVFDRGGNRYA--GRVAALADAAREAGLE F-------------------------------------------------------------LPG-ARAVARYVRISPMK ARRVVNLVRGLPAKEALTVLQFA---------------------------------PQAASEQVYKVLASAIAN----A- ENNE-RLDPDALLVSEAYVDEGPTMKRFQPRAQGRAYRIRKRTCHITVVVEATVKVKKGDTVVVIAGK------DK-GAK GKVIAAYPRQD--KVL--VEGVNRVKKHTR-ISTTQ--RG-AKT-GGIVTQEAPIHVSNVM-VVD-SD-------GK--P --TRVGYRI---DE-N-------GKVR---IARSTG---KDL--MGQKVHPHGFRLG--IS-TDWKSRWFA------D-K L--YKDYIGEDVKIRRMM--SKGLE-----RAGISKVDIERTR-D-RVRVDIHTARPGIVIGRKGAEADRIRGKLEKLVQ LNIIEVKS---PESDAQLVAQGVAEQLSSRVSFRRAMRKAMQSAMKNPVCKGIRVQVSGRLGGAEMSRTEFYREGRVPL- -HTLRANIEYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANQAYHDRVTM-PYSKIKANIAEVLKAEGYISTWL VEE----P---E-ESVVGKRLVVELKYG---QNR-------E---RSLAGIKRVSKPGLRVYAKSGELPRVLGGLGVAII STSQGLLTDRQARKRSVGGEVLAFVWMAGQKIRIRLKAYDHEVVDSSARKIVETVTRTGAQVAGPVPLPTEINRFCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVVSDKMEKTVVVEVEDRVKHALYG KIMRRTSKLKVHDEQ--NSAGIGDRVLIMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFIDD-HLLKKVETQND---KGTKN----VIKTWSRRSTIIPEMLGHTIAVHDGRKHVPVFVTE-AMVGH KLGEFALTRTFKGHE------K--DDR----KSR------RR >ACTINO_Salinispora_tropica_CNB-440 Concatenation of 2 sequences MAIRKYKPTTPGRRGSSVADFAE-ITRS------------TP-EKSLLTPLPKKGGRNAHGRITARH-QGGGHKRQ---- YRIIDFK-RV-DK-DGVPAKVAHIEYDPNRTARIALLHFL-DGEKRYILAPKDLKQGDIVESGP-G-AD-IKPGNNLPLR NIPVGMTIHNVELRPGGGAKLARSAGTGIQLLGR--EGAYATLRMPSGEIRRVDVRCRASIGEIGNADQSNINWGKAGRM -RWK-----GKR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---QGKPEG--RTR-RKGQPSD-R-LIVRRR --------------------------------MDRQVKG-ILGAKLGMTQVW--DNNR---------VVPVTVVQAGPCV VSQVR----SQE----K--DGY--AAVQLAY-------GA--IVKK----------PISGHYK----------------- ---AD-VAPRRHIVELRT--------TDAGEY-----SS---GQ-EVTV--E-E-FPAGISVDVTGKTKGKGYAGPMKRH GFHG-LRASHGVERKHRS-PGSIGGC-ATPG-RVFKGTRMAGRMGGVRYTVQNLTVQAVDTENN---------------- ----------LLLVRGA-IPGPKGALVLVR-MTTVDVLT-VEGTKA-GSVELPADIF----DA-QA-NIALMHQVVVAQL AAARQGTHKTKTRGE--------VA-GGGKKPY---------KQKGTGRAR--------QGS---IR-AP----QF---- AGGGVVHGPV-P-RDYSQRTPKKMKAAALRGALSDRARAD----------------K-VHVVEAF--VAGEK-------- --PSTKLVV--LSSTD--E---LNWVSLRNEPRVH-L---------------IESGQLNTYDVLLADD----VVFTKEAL EEFLPRLKERYRNEI----VGQLREQYQYGNPMQVPGLVKIVVNMGVG-EAARDAKLIDGAVRDLATITGQKPQVRRATK SIAQFKLREGMPIGAKVTLRGDRMWEFLDRLLSIALPRIRDFRGLDG-RKLDGNGNYTFGLTEQSVFHEID-----QDKI DRQRGMDITVVTT-----------------------ATTDDEGRALLKFLGFPFMSRIG-R--KSIPVPTGVDVT-I--- -A-G--Q-TVTVKGPKGELSHTI-AEP----ITIDRAEDGQ--LNV---AR-P--NDERKAK-ELHGLSRTLVANMIVGV TEGYRKSLEIAGTGY--RVTAKG-KD--LEFA--LGFSHPVTVVA-P-E-GITFSVE--K-PTLFHVAG-INKQLVGEVA ANIRKIR------PPEPY---KGKGVKYQGEVIRRKAGK----------MIQQESRLRVADNTGAREILCIRVLG-SGRR Y--ASIGDVIVATVKDAIPG-A-------GVKKGDVVKAVVVRTAKEKRRPDGSYIRFDENAAVIIK-DGGD-PRGTRIF GPVGRELR-DKRFMKIISLAPEVLIK-V--HHLRPAPGA-KTTKTRVG-RGEGSK--GKTAGRGTKGSKARKN---I--- -SAAF-E-GGQMPIHMRLPKMKG--FKNVNLERLVGPAELVDA-GAVRVK---------VLG--TGD-LGG-V-T-LQV- SAHAFSASAKEKITAAGGSI-K---PHH--PDR---SGAS-KGGNRVVFG----------EFGIQAL--EPAYVTNRQIE SARIAMTRHI------KRGGKVWITIFPDQALTKKPAETRMGSGK---------GSPEWWVANVKP-GRVLFEM--SF-- PNEQIAREAMRRAIHKLPMKCRI-VRAVGRARRHFRVRRQV---SGTPARPRLVVTRSLRHMVAQIVDD---T--KGHTL VSASTL-DASL-RG------TEG-DKSVLAGKVGVLLAER--AKAAG-IAKVVFDRGGNRYA--GRVAALADAAREAGLE F-------------------------------------------------------------LPG-ARAVARYVRISPMK ARRVVNLVRGLPAKEALTVLQFA---------------------------------PQAASEQVYKVLASAIAN----A- ENNE-RLDPDALLVSEAYVDEGPTMKRFQPRAQGRAYRIRKRTCHITVVVEATVKVRKGDTVLVIAGK------DK-GAK GKVIAAYPRQD--KVL--VEGVNRVKKHTR-ISTTQ--RG-AKT-GGIVTQEAPIHVSNVM-VLD-SD-------GK--P --TRVGYRI---DD-N-------GKVR---IARSTG---KDL--MGQKVHPHGFRLG--IS-TDWKSRWFA-------DK L--YKDYVGEDVKIRRMM--SKGLE-----RAGISKVDIERTR-D-RVRVDIHTARPGIVIGRKGAEADRIRGKLEKLVQ LNIIEVKS---PESDAQLVAQGVAEQLSSRVSFRRAMRKAMQSAMKNPVCKGIRVQVSGRLGGAEMSRTEFYREGRVPL- -HTLRANIEYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANQAYHDRVTM-PYSKIKANIAEVLKSEGYISTWL VEE----P---E-ESAVGKRLVVELKYG---QSR-------E---RSLAGIKRVSKPGLRVYAKSGELPRVLGGLGVAII STSQGLLTDRQARKRSVGGEVLAFVWMAGQKIRIRLKAYDHEVVDSSARKIVETVTRTGAQVAGPVPLPTEINRFCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGLVVSDKMDKTVVVEVEDRVKHGLYG KIMRRTSKLKVHDEQ--NSAGIGDRVLIMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFIDD-HLLKKVETQND---KGTKN----VIKTWSRRSTIIPEMLGHTIAVHDGRKHVPVFVTE-AMVGH KLGEFALTRTFKGHE------K--DDR----KSR------RR >ACTINO_Sanguibacter_keddieii_ST-74,_DSM_10542 Concatenation of 2 sequences MGIRKYKPTTPGRRGASVADFVE-ITRS------------EP-EKSLIRPLHKTGGRNSSGRITTRH-KGGGHKRA---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPNKLRQGDAIENGA-G-AD-IKPGNNLPLR NIPTGTVIHAIELKPGGGAKIARSAGVSVQLVAK--DGNFAQLRMPSGEIRNVDLRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GKR-P-TVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQAEG--RTR-RPNKASD-K-LIVRRR --------------------------------NERPVTA-VLGTKLGMTQVWD-EAGR---------LVPVTVVQVGTNV VTQVR----TAE----L--DGY--AAVQLAY-------GQ--IVSQ----------PLKGHFK----------------- ---AG-VTPRRHVTEIRT--------SDAGEF-----TL---GQ-ELTA--E-A-FASGSVVDVIGTTKGKGFAGVMKRH GFHG-VGASHGAHKNHRK-PGSIGGA-STPS-RVFKGVRMAGRMGVDRQTTQNLTVHAVDAEKG---------------- ----------LLLVKGA-VPGPKGGVVLVRETLTVDVID-AKGKKA-GTADLPAEVF----DV-QT-NIPLIHQVVVAQL AAARQGTHDTKNRGE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPT-P-RDYSQRTPKKMKAAALRGALSDRARAG----------------R-IHVVTGF--GIDGS-------- --PSTKLVV--LERGD--E---LTVKSLRNAEQVH-L---------------LVADQLNTYDVLVSDD----VVFTKGAL DAFLPRLKARYAAEI----LPALHEEFSHENVNQVAGLTKIVVNMGVG-DAAKDAKLIEGAIRDLTAITGQKPQVTKARK SIAQFKLREGMPIGAHVTLRGDRMWEFADRLLSIALPRIRDFRGLSP-KQFDGHGNYTFGLNEQSMFHEID-----PDKV DRVRGMDITIVTT-----------------------ATTDAEGRSLLKRLGFPFMSRIG-K--VPVPVPSGVDVS-I--- -S-G--A-LVTVKGPKGTLEHVI-PAP----IEVSLAEDGA--LAV---TR-P--NDERTSR-ALHGLTRTLLANIITGV TEGYEKKLEIVGTGY--RVTAKG-SE--LEFA--LGFSHPVVISA-P-E-GITFAVE--A-PTKFSVSG-IDKQQVGEVA ANIRKIR------KPEPY---KGKGVRYAGEIVRRKAGK----------MIQQESRLRVADNTGAKEILCIRVLG-SGRR Y--AGIGDTIVATVKDAIPG-G-------NVKKGDVVKAVIVRTAKERRRPDGSYIKFDENAAVILK-ADGE-PRGTRIF GPVGRELR-DKKFMKIISLAMEVLLK-V--HHLRPAPGA-KTAKTRVG-RGHGSK--GKTAGRGTKGQKARYQ---V--- -PERF-E-GGQMPLHMRLPKLRG--FKNVNLEKLVTVDDLVAK-GAVRVK---------VLG--TGE-I-T-V-K-LDV- TVDRLSSSAKDKILAAGGSV-K---QHH--PGR---SGAA-TGGTTIAFG----------EYGIQAL--EPAYVTNRQIE AARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRIVFEL--AG-- VPEELAREAMRRAIHKLPMKCRF-VKAVARQRRHLRLRKKI---SGTAAQPRLVVTRSARHMTAQVVDD---T--VGKTV ASASTL-EADL-RAFD------G-DKTAKARKIGELVAER--AKAAG-VEAVVFDRGGNKYH--GRVAAVADGAREGGLA L--------------------------------------------------------------ME-AKAQVRFIRVTPQK ARRVVDLIRGKQATEAVAVLKFA---------------------------------PQAASEPIRKVVESAIANARVKA- DRASVAFDEQQLVVTAAFVDEGPTLKRFRPRAQGRASQILKRTSHITVVVAPMAKIKKGDTVIVIAGR------DK-GKT GRVLEVLTDSD--RVI--VEGVQRVTKHVK----VG-QTQRGTRTGGIESVEAPIHVSNVQ-FYDAEA-------KR--G --KRIGART---EQ-----VERDGRVR---VTRGHGDTAKDI--MGQKVHPHGYRLG--IT-TDHRSRWFA-DSTKPG-Q R--YRDYVREDVQIRKLM--STGLE-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---AEIDAQLVAQGIAEQLASRVSFRRAMRKGMQSAQRA-GAKGIRVQCAGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHETVQM-PFSKLKSHIAEILQAEGYISGWT VED----A---P----VGKYLTIQLKFG---PSR-------E---RSLAGIRRISKPGLRVYAKSTNLPKVLGGLGVAIL STSSGLLTDKQAAQKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVFCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKLRKTRRGYVVSDKMDKTVVIEVEDRVKHPLYG KVIRRTSKVKAHDEQ--NSAGTGDLVLIMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLQKKVDVQNE---KGTKN----VIKTWSRRSVITPDFLGHTFAVHDGRKHTPVFVTE-SMVGH KLGEFAPTRTFRGHV------K--DDK----KGR------RR >ACTINO_Slackia_heliotrinireducens_RHS1,_DSM_20476 Concatenation of 2 sequences MGVKQYKPTSPGRRFQTVSDFAE-ITTD------------KP-EKSLLAPLPKKAGRNNNGRITTRH-QGGGNKRR---- YRIIDFK-R--NK-DGVPAKVATIEYDPNRSARIALLHYV-DGEKRYILHPKGLQVGDMVVSGP-N-AD-IKPGNAMPLA DIPVGTLIHAVELQPGRGAALARSAGTSIQLMGK--EGNYAILRMPSSEMRRVLLTCRATIGEVGNADHANVKIGKAGRN -RWK-----GIR-P-TVRGTVMNPVDHPHGGGEGKNKT--AGRH-PVSP---WGVPTKGHRTR-NPKKASS-R-LIIRRR --------------------------------MIN---A-IYGKKIGMTQLFN-EDEK---------VVPCTVIVAEPNK VCQIK----TTD----T--DGY--EAVQLGF-------GA--IVNK----------PMAGHFK----------------- ---LG-TEPTRYLREVRV--------ENAADY-----KV---GD-LQTV--E-A-FADVKKVHVTGTSIGKGFQGVIKRH GFRG-GPGGHGA-HFHRA-PGSVGMC-ATPS-RVLKGVRMPGHMGCNTVTTKNLEVVRIDAEQN---------------- ----------LILVKGA-VPGAKGGIVRVR-MATIEIKN-ASGEKA-SEVELESAVF----GI-EP-NVHVMHTVVRSQQ AAMRQGTHDTKTRGE--------VR-GGGKKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- AGGGTVFGPH-P-RSYAFRVNRKEVKLAMRSALSAKLADG----------------Q-LMVVEDF----KFE-K------ --PCTKTIV--IPNDD--V---NAYLSFRNIPKVN-V---------------ISVGEANTMELIDNKV----LVLTASTL KRLEPRLKEKYQNEI----IAKLEKELNIDNINKVPRLEKIVVNMGVG-EAASDSKQLDAAMNDMRIITGQQPCVTRAKK SIAAFHIRQGMAIGCKVTLRGDRMWEFLDRLLSMALPRVRDFRGIPT-TSFDGRGNYTLGVTEQLIFPEIE-----YDKI DRTRGMDITFVTT-----------------------AENNEAAKALLDALGFPFMSRIG-K--KPIPVPAGVDVA-I--- -E-G--N-TITVKGPLGELTYTY-PVV----ITVAQEG-DE--IIV---TR-P--NDERQNR-AYHGLVRSLINNMVEGV SKGFSKRLELVGVGY--RAALKG-GK--LEMQ--LGYSHPVIVEA-P-E-GITLEVP--D-QTHIVVKG-CDKQLVGETA AVIRKWR------KPEPY---KGKGIRYEGEYVRRKLGK----------MIQMQSMLNVADNSGARKVQCIKVIG-SKRR Y--AGLGDVIICSVKEAAPN-G-------NVKKGDVVRCVVVRVKKQIRRTDGSYIRFDQNAAVLIN-NDGS-PRGTRIF GPVARELR-EKKYMKIVSLAPETLME-L--SDLRPNPGS-THKRKRVG-RGPASGH-GKTAGRGMNGQKSRAGGG-K--- -GAGF-E-GGQTPLAMRLPKLGG--FRNVNVSRIVDHDSLVAK-GIIKVK---------VLG--DGE-I-T-K-A-VTV- KVDKVSASAAAKIEAAGGKV-K---VQR--GSM---KGKA-KGYTKLNHG----------DYGIQAL--EAHWITNRQIE AARVAMTREM------KRGGKVWITIFPDKPITQKPAETRMGSGK---------GNPEGWVAVVKP-GRIMFEI--AG-- VEDAVAREALRLAINKLPIKCKI-VKQAALARRHRRVRGKV---SGTAARPRLCVTRSNSNIYVQFVDD---V--EGKTL YGESTL-GADF-KATG----KSG-ATVEGAEALGQIVGKK--AIEKG-ITEIVFDRGGNLYH--GRVKALAEGAREAGLK F--------------------------------------------------------------ME-AKATAKYVRVSPRK ARIVLDQIRGKDVARAREILMFS---------------------------------ERAISETILKVLDSAVAN----A- TNNH-DMSANNLVVKTTYADEGPTMKRFTPRAKGSASRIRKRTSHITVIVAPKLHVRKGDKVLVIAGK------DK-GKE GVVLKALPQKE--RVV--VEGCGVVKKALR----PT--QQ-NPQ-GGIIHKEAPIHVSNVQ-IVCPKC-------GK--A --TRVTNKR---ND--------EGRVR---VCKKCG---ADI--MGQKVMPTGFRLG--IT-EDWRSRWYA------D-K D--YAKNLENDLAIRKFL--EKQLE-----KAAVSKIEIERAG-D-KIKIIITTARPGVVIGKKGAEIENLRKDVAKVVN IEVIEVKR---PELDAVLVAKSVAEQLEGRVAFRRAMRKAVQSARKS-GAQGIRIQCSGRLGGAEMSRREWYREGRVPL- -HTLRAKIDYGFATARTTMGAIGVKVWIYMTMNDPIADMLTRVRNANSAGKPTVSM-PSSKKLVEIARIMTEEGYVQGYE TIE----S---Q----PRDILEITLKYG---EKK-------S---KVIRGIKRISKPGLRIYAGKDELPRVLGGLGTAIV STSKGVMTDRDARKAGVGGEVIAYIWVANQKIRIRLKGYDHEIVDQSTKLIVDTAQKTGAKVSGPIPLPTERNLYCVVRG PHVDKDSR-EQFEMRTHKRLIDILEPTQSTVDSLMRLDLPAGVDIEIKLRKVRQGVVVSAVNDKTIVVETKERKPHPVYG KMMTTTKKFHAHDEN--NECGVGDTVQIMETRPLSKMKRWRLVKIIEKA------------------------------- -----M-KKGPFVEP-RLLGRIQAMNA---AGEKN----VVKTWSRASTIFPEMVGHTIAVHDGRKHVPVYVTE-SMVGH KLGEFAPTRTFKGHA----------DK----KKK-------- >ACTINO_Streptomyces_avermitilis_MA-4680 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-VTRS------------TP-EKSLVRPLHSKGGRNNAGRVTVRH-QGGGHKRA---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYILAPRNLQQGDRVENGP-G-AD-IKPGNNLALR NIPVGTTVHAIELRPGGGAKFARSAGASVQLLAR--EGAMATLRMPSGEIRMVDARCRATVGEVGNAEQSNINWGKAGRK -RWL-----GVR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-SPKKASS-K-YIVRRR --------------------------------MAKQIKG-ILGEKLGMTQVWD-ENNR---------VVPVTVVKAGPNV VTQVR----TND----S--DGY--ESVQIAF-------GE--IVNK----------PLKGHFK----------------- ---AD-VTPRRHLVEIRT--------ADASEY-----TL---GQ-EITA--E-T-FEAGVKVDVTGKSKGKGFAGVMKRH NFKG-LGAGHGTQRKHRS-PGSIGGC-ATPG-RVFKGLRMAGRMGNERVTTQNLTVHAVDAEKG---------------- ----------LLLIKGA-VPGPNGGLVLVR-MSTIDILS-PSGDNA-GTVELPAEIF----DVEKI-SIPLLHQVVVAQL AAARQGTHKVKRRGE--------VR-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPT-P-RDYSQRTPKKMKAAALRHALTDRARNA----------------R-IHVITGV--IEGET-------- --PSTKLLV--IERSD--E---AALLSARNLPQVH-I---------------LEPGQLNTYDVLVSDD----VVFTQAAF ESFVPRLKTKYREEI----AGKLQEEFSYENVMQTPGLVKIVVNMGVG-DAARDSKLIDGAIRDLTTITGQKPAVTKARK SIAQFKLREGQPIGAHVTLRGDRMWEFLDRTLSLALPRIRDFRGLSP-KQFDGRGNYTFGLTEQVMFHEID-----QDKI DRVRGMDITVVTT-----------------------ATNDAEGRALLRHLGFPFMSRIG-K--LPITVPAGVDVT-I--- -D-G--R-TVQVKGPKGSLSHTI-AAP----IEIAKGEDGV--LNV---TR-P--NDERQNK-ALHGLSRTLVANMITGV TQGYVKKLEISGVGY--RVLAKG-SN--LEFS--LGYSHSITVEA-P-E-GITFKVE--A-PTRFSVEG-IDKQKVGEVA ANIRKLR------KPDPY---KAKGVKYEGEVIRRKVGK----------MIQQESRLRVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVILK-NDGD-PRGTRIF GPVGRELR-EKKFMKIISLAPEVLLK-I--HNLRPAPGA-KTAKTRVG-RGEASK--GKTAGRGTKGTKARYQ---V--- -PERF-E-GGQMPLHMRLPKLKG--FKNVNLDKLVTVEGLVAK-GAVRVK---------VLG--QGE-I-S-V-A-LQV- TVDAVSGSAKEKITAAGGTV-K---QHH--PKR---RGQA-KGGTQVSFG----------EYGIQAL--TPAYVTNRQIE AARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVHP-GRVMFEL--SY-- PNEKIAREALTRAAHKLPMKCRI-VKRAAIKRRHIRIRKHI---SGTAERPRLVVTRSNRHIVAQVIDD---V--KGHTL ASASTL-DTTI-RG------GES-DKSAQAKSVGALVAER--AKAAG-VEAVVFDRGGNQYA--GRIAALADAAREAGLK F--------------------------------------------------------------ME-ARAQARYIRVTPMK ARRVVDLIRGMDATEAQAVLRFA---------------------------------PQAASVPVGKVLDSAIAN----A- AHNYDHTDADSLFISEAYVDEGPTLKRFRPRAQGRAYRIRKRTSHITVVVSS-MKIKKGDTVQVITGK------DK-GKQ GKVIAAYPRDE--RVL--VEGVNRVKKHTK--AGPT-AGG-SQA-GGIVTTEAPIHVSNVQ-LVVEKD-------GN--K VVTRVGYRF---DD--------EGKIR---VAKRTG---EDI--MGQKVNPHGFRLG--IT-TDFKSRWYA------D-K L--YKDYVKEDVAIRRMM--TSGME-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGDLEKLVQ LNILEVKN---PETDAQLVAQAVAEQLSSRVSFRRAMRKSMQSAMKA-GAKGIKIQCGGRLGGAEMSRSEFYREGRVPL- -HTLRANVDYGFFEAKTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDTVGM-PHSKIKSHIAEILQQEGFITGWK VED----A---E----VGKNLVLELKFG---PNR-------E---RSIAGIKRISKPGLRVYAKSTNLPKVLGGLGVAII STSHGLLTDKQAGKKGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSAKKIVETVTRTGASVAGPVPLPTEKNVYCVIKS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKTREGLVVSDKMDKTVVVAVEDRVKHALYG KVIRRTNKLKAHDEQ--NAAGVGDRVLLMETRPLSATKRWRVVEILEKA------------------------------- -MPRSL-KKGPFVDD-HLIKKVDAQNE---AGSKN----VIKTWSRRSMIIPAMLGHTIAVHNGKTHIPVFVTE-SMVGH KLGEFSPTRTFRGHV------K--DDR----KSK------RR >ACTINO_Streptomyces_coelicolor_A3(2) Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-VTRS------------TP-EKSLVRPLHSKGGRNNAGRVTVRH-QGGGHKRA---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYILAPRNLQQGDRVENGP-G-AD-IKPGNNLALR NIPVGTTIHAIELRPGGGAKFARSAGASVQLLAK--EGTMAHLRMPSGEIRLVDQRCRATVGEVGNAEQSNINWGKAGRK -RWL-----GVR-P-TVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGKKEG--RTR-SPKKASN-K-YIVRRR --------------------------------MTKQIKG-ILGEKLGMTQVWD-ENNR---------VVPVTVVKAGPNV VTQVR----TND----V--DGY--ESVQIAF-------GE--IVNK----------PLKGHFK----------------- ---AD-VTPRRHLVEIRT--------AAASEY-----TL---GQ-EITA--E-A-FESGVKVDVTAKSKGKGFAGVMKRH NFKG-GKASHGAHRVHRM-PGSIGGC-ATPG-RVFKGMRMAGRMGNERVTTQNLTVHAVDAEKG---------------- ----------LLLIKGA-VPGPNGGLVLVR-MSTVDILS-PAGEKT-GSVELPAEIF----GV-EKISIPLIHQVVVAQN AAARQGTHKTKRRGE--------VR-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPQ-P-RDYSQRTPKKMKAAALRHALTDRARHN----------------R-IHVVTGV--IEGEN-------- --PSTKLLV--VDRAD--E---AAWLSARNLPQIH-I---------------LEPGQLNTYDVLVSDD----VVFTQAAF ESFVPRLKTKYREEI----AGKLREEFSYENVMQIPGLVKIVVNMGVG-DAARDSKLIEGAIRDLTTITGQKPAVTKARK SIAQFKLREGQPIGAHVTLRGDRMWEFLDRTLSLALPRIRDFRGLSP-KQFDGRGNYTFGLTEQVMFHEID-----QDKI DRTRGMDITVVTT-----------------------ATNDAEGRALLRHLGFPFMSRIG-K--LPIAVPAGVDVT-I--- -D-G--R-TVSVKGPKGSLTHTV-VAP----IDIAKGEDGV--LNV---TR-P--NDERQSK-ALHGLSRTLVANMITGV TQGYVKKLEISGVGY--RVLAKG-SN--LEFS--LGYSHPILVEA-P-E-GITFKVE--N-PTHFSVEG-IDKQKVGEVA ANIRKLR------KPDPY---KAKGVKYEGEVIRRKVGK----------MIQQESRLRVADNTGAKEILTIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVILK-NDGD-PRGTRIF GPVGRELR-EKKFMKIISLAPEVLLK-I--HNLRPAPGA-KTAKTRVG-RGEASK--GKTAGRGTKGTKARYQ---V--- -PERF-E-GGQMPLHMRLPKLKG--FKNVNLDKLVTVEGLVAK-GAVRVK---------VLG--QGE-I-S-V-A-LQV- TVDAVSGSAKEKITAAGGTV-K---QHH--PKR---RGMA-KGGTQVAFG----------EYGIQAL--TPAYVTNRQIE AARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVHP-GRVMFEL--SY-- PNEKIAREALTRAAHKLPMKCRI-VKRAAIKRRHIRIRKNL---SGTAERPRLVVTRSNRHIVAQVIDD---I--KGHTL ASASTL-DTSI-RG------GEA-DKSAQAKQVGALVAER--AKAAG-VEAVVFDRGGNQYA--GRIAALADAAREAGLK F-------------------------------------------------------------TME-ARAQARYIRVTPMK ARRVVDLIRGMDATEAQAVLRFA---------------------------------PQAASVPVGKVLDSAIAN----A- AHNYDHTDADSLFISEAYVDEGPTLKRFRPRAQGRAYRIRKRTSHITVVVSS-MKIKKGDLVQVITGK------DK-GKQ GKVIAAFPRED--RVL--VEGVNRVKKHTK--AGPT-ARG-SQA-GGIVTTEAPIHVSNVQ-LVVEKD-------GN--K VVTRVGYRF---DD--------EGKVR---VAKRTG---EDI--MGQKVNPHGFRLG--IT-TDFKSRWYA------D-K L--YKDYVKEDVAIRRML--TSGME-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADKIRGQLEKLVQ LNILEVKS---PETDAQLVAQAVAEQLSSRVSFRRAMRKSMQGTMKA-GAKGIKIQCGGRLGGAEMSRSEFYREGRVPL- -HTLRANVDYGFFEAKTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDSVTM-PASKIKSHIAEILQQEGFITGWK TED----A---E----VGKNLTLELKFG---PNR-------E---RSIAGIKRISKPGLRVYAKSTNLPKVLGGLGVAII STSHGLLTDKQAGKKGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSAKKIVETVTRTGASVAGPVPLPTEKNVYCVIKS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKTRQGLVVSDKMDKTVVVAVEDRVTHALYG KVIRRTEKLKAHDEQ--NAAGVGDRVLLMETRPLSATKRWRVVEVLEKA------------------------------- -MPRSL-KKGPFVDD-HLIKKVDTQNE---AGTKN----VIKTWSRRSMIVPAMLGHTIAVHNGKTHIPVFVTE-SMVGH KLGEFSPTRTFRGHV------K--DDR----KSK------RR >ACTINO_Streptomyces_griseus_subsp_griseus_NBRC_13350 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-ITRS------------TP-EKSLVRPLHSKGGRNNAGRVTVRH-QGGGHKRA---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIVAPRGLSQGDRVENGP-T-AD-IKPGNNLALR NIPVGTTIHAIELRPGGGAKFARSAGASVQLLAK--EGTMAHLRMPSGEIRLVDARCRATIGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQKEG--RTR-SPKKASN-K-YIVRRR --------------------------------MSKNIKG-VLGEKLGMTQVWD-ENNR---------VVPVTVVKAGPCV VTQVR----TND----S--DGY--EAVQIAF-------GE--IVNK----------PLKGHFK----------------- ---AD-VTPRRHLVELRT--------PDASEY-----TL---GQ-EVTA--E-V-FESGVKVDVTGKSKGKGFAGVMKRH NFKG-LGAGHGTQRKHRS-PGSIGGC-ATPG-RVFKGMRMAGRMGNERVTTQNLTIHAVDAEKG---------------- ----------LLLIKGA-VPGPNGGLVLVR-MSTIDILS-PAGDKA-GTVDLPAEIF----DA-KT-SVPLIHQVVVAQL AAARQGTHKTKRRGE--------VR-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGVVHGPQ-P-RDYSQRTPKKMKAAALRGALSDRARHS----------------R-IHVVTGV---VEGA-------- --ASTKLLV--VDRAD--E---AAWLSARNLPQVH-I---------------LEPGQLNTYDVIVSDD----VVFTQAAF ESFVPRLKTRYREEI----AGKLREEFSYENVMQVPGLVKIVVNMGVG-DAARDSKLIDGAVKDLTTITGQKPAVTKARK SIAQFKLREGQPIGCHVTLRGDRMWEFLDRTLSLALPRIRDFRGLSP-KQFDGRGNYTFGLTEQVMFHEID-----QDKI DRVRGMDITVVTT-----------------------ATNDDEGRALLRHLGFPFMSRIG-K--LPIQVPAGVDVT-I--- -D-G--R-TVAVKGPKGSLTHTV-AAP----IEVSKGEDGV--LNV---TR-P--NDERQNK-ALHGLSRTLVANMITGV TAGYSKALEISGVGY--RVQAKG-SN--LEFA--LGYSHPILIEA-P-E-GITFKVE--S-PTKLSVEG-IDKQKVGEVA ANIRKLR------KPDPY---KAKGVKYAGEVIRRKVGK----------MIQQESRLRVADNTGAKEILTIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTVKERRRQDGSYIRFDENAAVILK-NDGD-PRGTRIF GPVGRELR-EKKFMKIISLAPEVLLK-A--HNLRPAPGA-KTAKTRVG-RGEASK--GKTAGRGTKGTKARYQ---V--- -PERF-E-GGQMPLHMRLPKLKG--FKNVNLDKLVTVADLVAK-GAVRVK---------VLG--QGE-I-S-V-A-LQV- SVDAVSGSAKEKITAAGGTV-K---QHH--PKR---SGMS-KGGTQVAFG----------EYGIQAL--TPAYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRVMFEL--SY-- PNEKIAREALTRAAHKLPMKCRI-VKRAARKRRHIRVRKHL---SGSPERPRLVVTRSNRHIVAQVIDD---I--AGHTL ASASTL-DTSI-RG------GEG-DKSAQAQQVGALVAER--AKAAG-VEAVVFDRGGNQYA--GRIAALADAAREAGLK F-------------------------------------------------------------TME-ARAQARYIRVTPMK ARRVVDLIRGMDATEAQAVLRFA---------------------------------PQAASVPVGKVLDSAIAN----A- AHNYDHTDASSLVISEAYVDEGPTLKRFRPRAQGRAYRIRKRTSHITVVVSS-MKIKKGDLVQVITGK------DK-GKQ GKVIVAYPAQD--RVL--VEGVNRVKKHTK-AGQTA--RG-SQT-GGIVTTEAPIHVSNVQ-LVVEKD-------GN--K VVTRVGYRF---DD-E-------GKIR---VAKRTG---EDI--MGQKVNPHGFRLG--IT-TDFKSRWYA------D-K L--YKDYVKEDVAIRRMM--TKGME-----RAGISKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---PEVDAQLVAQAVAEQLSSRVSFRRAMRKSMQSSMKA-GAKGIKIQCGGRLGGAEMSRSEFYREGRVPL- -HTLRANVDYGFFEAKTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDSVVM-PHSKIKSHIAEILQQEGFITGWK VED----A---E----VGKNLVLELKFG---PNR-------E---RSIAGIKRISKPGLRVYAKSTNLPKVLGGLGVAII STSHGLLTGQQAGKKGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSAKKIVETVTRTGASVAGPVPLPTEKNVYCVIKS PHKYKDSR-EHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLRKTREGLVVSDKMDKTVVVAVEDRVKHALYG KVIRRTNKLKAHDEQ--NSAGVGDRVLIMETRPLSASKRWRIVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLIKKVDVQNE---AGTKN----VIKTWSRRSMIVPAMLGHTIAVHNGKIHVPVFVTE-SMVGH KLGEFSPTRTFRGHV------K--DDR----KSK------RR >ACTINO_Streptosporangium_roseum_NI_9100,_DSM_43021 Concatenation of 2 sequences MGIRKLKPTTPGRRGASVSDFSE-ITRS------------TP-EKSLLAPLHSKGGRNVHGRVTTRH-QGGGHKRA---- YRIIDFR-RH-DK-DGIPAKVAHIEYDPNRTSRIALLHYA-DGEKRYILCPTGLKQGDLIENGP-A-AD-IKPGNCLPLR NIPTGTFIHAVELRPGGGAKLGRSAGAQIQLLAK--EGQYATLRMPSGEMRQVDVRCRASIGQVGNAEQANINWGKAGRM -RWK-----GKR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---KGKPEG--RTR-AANKASD-R-LIIRRR --------------------------------MAKQIKG-VLGKKLGMTQVFD-ADNR---------MVPVTVVEAGPCV VTRVR----TPE----K--DGY--SAVQLGF-------GQ--VVNK----------PLGDYLR----------------- ---KHDITPRRYFAEIRT--------EDAGDY-----TL---GQ-ELSA--D-T-FEAGQFVDVTGKSKGKGFAGVMKRH GFKG-LSASHGTQRKHRS-PGSIGGC-ATPG-RVFKGLRMAGRMGNVRTTVQSLKVHAVDAEKG---------------- ----------LILIKGA-IPGANGSLVLVR-MSTIDVLD-VSGAKT-GTVDLPGDIF----DA-KV-NIPLIHQVVVAQL AARRQGTHKAKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- AGGGIVHGPL-P-RDYSQKTPKKMKAAALRGALSDRANGG----------------R-VHVVSAL--VQGET-------- --PKTKLVV--VDEGD--E---LTWLSLRNAPEVH-L---------------LDAGQLNTYDVLCYDD----VVFTQEAY DQVVPRLKQRYREEI----IAKLHEEFGFENIMLVPTITKIKVNMGVG-EAARDSKLIDGAVRDLTVITGQKPAVVRARK SIAQFKLREGMPIGAHVTLRGDRMWEFLDRLLSLALPRIRDFRGLSP-KQFDGNGNYTFGLTEQVMFHEID-----QDKV DRQRGMDITVVTT-----------------------AKTDDQGRALLKLLGFPFMSRIG-R--LPIPVPNGVDVA-I--- -D-G--R-DVTVKGPKGTLSHKV-AEP----IDVAKGDDGT--VTV---SR-P--NDENKVR-ALHGLSRTLIANMVTGV TQGYSKTLEIVGVGY--RVQAKSPTQ--LEFA--LGFSHPVIVDA-P-E-GVSFRVE--K-PTLFHVDG-IDKQKVGEIA ANIRKLR------KPDPY---KGKGVRYQGEVIRRKVGK----------MIQQESRLKVADNTGAKEVLCIRVLG-SGRR Y--AGIGDIIVATVKDAIPG-G-------TVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVIIK-DSGD-PRGTRIF GPVGRELR-DKKFMRIISLAPEVLLR-I--HHLRPAPGA-NKSKVRKG-RGEASK--GKTAGRGTKGTRARNK---V--- -PLGF-E-GGQVPLQRRLPKMKG--FSNVNLDKLVTVETLVAK-GAVRVK---------VLG--TGD-I-S-V-A-LNV- QAHAFSASAKEKITAAGGSV-K---QHR--PDR---HGAA-KGGTRVVFG----------EFGIQAL--EHSYVTNRQIE SARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRVMFEL--SG-- VAEPVAREALRRAMHKLPMKCRF-VRAVSRARRHGRVRKKV---VGTAARPRLVVNRSTRHLFVQIVDD---A--QGHTL VSASTM-ESSL-RA------DSG-AKTDKAKQVGELLAQR--AKAAG-ITAVVFDRGGNRYA--GRIAALADSAREGGLE F--------------------------------------------------------------ME-ARAQVRFARHTPMK ARRVVDLIRGLPASEAQAVLQFA---------------------------------PQSASETVYKVLSSAIAN----A- EHNF-KLDRDTLFVSRAWVDEGPTLKRFRPRAQGRAYRINKRTSHITVIVESKLHVKKGDLVQVIAGK------DK-GAK GRVIAAHPREE--RVV--VEGVNMIKKHSKETNQGP--RG-AKT-GGVQTMEAPIHVSNVK-KLKDD--------EK--P ------AKK---ES----------KAA---SDE-SG---EDN--MGQKVNPHGFRLG--IT-TDFKSRWYA------D-K L--YKSYVAEDVAIRRML--KKGME-----RAGISKVEIERTT-D-RVQVDIHTARPGIVIGRRGAEADRIRGDLEKLVQ LNILEVKN---PEIDAQLVAQGVAEQLSSRVSFRRAMRKAMQSAMKS-GAKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGLYEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAYHDTVAM-PYSKIKAHIAEILQQEGYIQAWS VED----A---K----VGKNLVVELKFG---PSR-------E---RSLAGLRRVSKPGLRVYAKKDNLPRVLGGLGVAII STSGGLMTDKQAGKRGVGGEVLAFVWMAGQKIRIRLKAYDHEVIDSSAKKIVETVTRTGAKVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDISIKLRKTREGLVVSDKMDKTVVVAVEDRVKHPLYG KVIRRTTKYKAHDEA--NACGVGDRVLLMETRPLSASKRWRVIEILEKA------------------------------- -MPRSL-KKGPFVDD-HLQKKVDVQNE---KGTKN----VIKTWSRRSMIVPDMLGHTIAVHDGRKHVPVFVTE-SMIGH KLGEFAPTRTFRSHV------K--EDR----RSR------R- >ACTINO_Thermobifida_fusca_YX Concatenation of 2 sequences MGIRKYKPTSPGRRGGSVSTFAE-ITRS------------KP-EKSLVRPLHSKGGRNGHGRITARH-QGGGHKRA---- YRLIDFR-RH-DK-DGIPAKVAHIEYDPNRTARIALLHYV-DGEKRYILAPVGLKQGDRVENGP-A-AD-IKPGNCLPLR NIPTGTFVHAVELKPGGGAKLGRAAGAAIQLLAK--EGAYATLRMPSGEMRQVEVACRATVGQVGNVEHANISWGKAGRM -RWK-----GKR-P-SVRGVAMNPIDHPHGGGEGRT-S--GGRH-PVSP---WGKAEG--RTR-KKGKPSD-R-LIVRRR --------------------------------TTKQIKG-VLGEKLGMTQVFD-ESGK---------VVPVTVLKAGPAV VTRVR----TPE----T--DGY--SAIQLGY-------GH--IVNK----------PLGDYLK----------------- ---HN-LTPRRHYVEVRT--------SDASEY-----TV---GQ-EITA--D-V-FQPGEKVDVTGKTKGKGYAGVMKRH GFGG-LGASHGTQRKHRS-PGSIGGC-ATPG-RVFKGMRMAGRMGNVRRTVQNLTVHSVDAEKG---------------- ----------LLLVKGA-VPGPNGGLVLVR-MATIEVKD-REGAAK-GSVELPDEIF----AQ-KV-NIPLIHQVVVAQQ AAGRQGTHSTKTRGE--------VR-GGGKKPY---------RQKGTGRAR--------QGS---VR-AP----QF---- TGGGTVHGPK-P-RDYAQRTPKKMKAAALRGALSNRAQHG----------------R-IHVVSEF--VPEDT-------- --KRTQLVV--LSRED--Q---HNRLALRNLPEVH-I---------------LDANQVNTYDVLYADD----IVFTEAGY QEFLPRLKQKYREEI----IPALREEFGYTNIMQVPGLTKIVVNMGVG-DAARDAKLIQGAIADLSAITGQKPKINRAKK SIAQFKLRQGQPIGASVTLRGDRMWEFLDRLLTLALPRIRDFRGLSA-KQFDGNGNYTFGLTEQVMFHEID-----PDKV DRQRGMDITIVTT-----------------------AATDEEGRSLLRRLGFPFMSRIG-R--QPISVPKGVEVT-I--- -D-G--K-DVKVKGPKGELKHTV--PP-S--ITVTLED-GQ--VKV---SR-A--DDRPQTR-SLHGLTRSLIANLIEGT SKGYTKTLEISGVGY--RVQAKG-RN--LEFS--LGYSHPIVVEP-P-E-GITFRVE--K-PTLLHVEG-IDKQKVGQVA ADIRSLR------KPDPY---KAKGIRYQGERIRRKAGK----------MIQQESRLKVADNTGAKELLTIRVLG-SGRR Y--ASIGDTIVATVKDALPG-A-------GVKKGDIVKAVVVRTTKERRRPDGFYIRFDENAAVLIK-DGGD-PRGTRIF GPVGRELR-DKKFMRIISLAPEVLLK-L--HHLRPAPGS-NKAKIRKG-RGEASK--GKTAGRGTKGTKARST---V--- -PAGF-E-GGQMPLIRRIPKLKG--FSNVNLDKLVTIEDLVAK-GAVRVK---------VLG--TGE-I-S-V-P-VRV- SANAFSSSAKEKILAAGGSV-K---QHH--PSL---RGRA-KGGTSVHFG----------EYGIQAL--ESAYVTNRQIE AARIAMTRHI------RRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWVAPVKA-GRVMFEL--AG-- VPEPVAKEALRRAIHKLPMKCKV-VRAAARARRHMRVRKKV---RGTPERPRLVVTRSLKHIVAQIVDD---T--KGHTL VSASTL-EASI-RG------EEG-RKTEKSHLVGKVLAER--AKAAG-ITAVVFDRAGYRYH--GRVAALANGAREGGLE F--------------------------------------------------------------MG-TRAQARFVRVTPRK ARRVVDLIRGLPAEEAQAVLRFA---------------------------------PQAASGPVGKVLASAIAN----A- EHND-KLDRETLVVSRAWVDEGPTLKRIRPRGFGRAFRVNKRTSHITVEVAP-MKIKKGDEVIVIAGK------DK-GAT GKVKKALPKEQ--RVI--VEGVNLIKKHKK----AN--QAGGQQ-GEVVTLEAPIHVSNVA-LLEDGR-----------P --TRVGYRF---KE--------DGKVR---ISRRTG---KEI--MGQKVNPHGFRLG--VT-TDFKSRWFA------D-K L--YKDYVKEDVAIRQML--TRGME-----RAGISKVEIERTR-E-RVRVDVHTARPGIVIGRRGAEADRIRANLEKLVQ LNILEVKN---PEIDAQLVAQGVAEQLSSRVAFRRAMRKAIQSAMKS-GAKGIRVQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGFFEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANAAYHETVAM-PYSKIKAHIAEILQKEGYIQGWR VED----A---R----VGKNLVVTLKYG---PTR-------E---RAIAGLRRVSKPGLRVYAKKDNLPRVLGGLGVAII STSSGLMTDKEAKKNGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDKSARRIVETVTRTGAQVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDIEIKLRKVREGYVVSDKMDKTVVVAVENRFKHPLYG KIIRRTTKYKAHDEA--NIAGVGDRVRLMETRPLSATKRWRVVEILEKA------------------------------- -MPRSL-KKGPFVDH-HLMKKVLEQNE---KGTKN----VIKTWSRRSMVVPEMIGHTIAVHDGRKHVPVFITE-AMIGH KLGEFAPTRTFRSHV------K--EDR----RSR------R- >ACTINO_Thermobispora_bispora_R51,_DSM_43833 Concatenation of 2 sequences MGIRKYKPTTPGRRGASVSDFSE-ITRS------------RP-EKSLLAPLHRKGGRNHHGRVTARH-QGGGHKRA---- YRIIDFR-RN-DK-DGIPAKVAHIEYDPNRTARIALLHYA-DGEKRYILAPVGLKQGDLVENGP-T-AD-IKPGNCLPLR NIPTGTFIHAVELRPGGGAKLARSAGAQIQLLAK--EGNYATLRMPSGEMRMVDVRCRATVGQVGNTEQANISIGKAGRN -RWK-----GKR-P-SVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVNP---KGKPEG--RTR-RPNKPSD-R-LIIRRR --------------------------------MARQIKG-VLGKKLGMTQVFD-EANR---------VVPVTVVEAGPCV VTRVR----TPE----K--DGY--SAIQLGY-------GQ--IVNK----------PLGDYLK----------------- ---HN-ITPRRYFAEIRT--------DDASEY-----TL---GQ-EITV--D-I-FQPGDYVDVTGRSKGKGFAGVMKRH GFRG-LGGSHGTQRKHRS-PGSIGAC-ATPG-RVFKGLRMAGRMGNARTTVQNLKVQAVDAEKN---------------- ----------LILVKGA-IPGANGSLVLIRMSTTIDVLD-ANGAKA-GTVELPEEIF----GA-KV-NVPLMHQVVVAQL AARRQGTHATKTRGD--------VS-GGGKKPY---------RQKGTGRAR--------QGS---IR-AP----QF---- TGGGTVHGPQ-P-RSYDQRTPKKMKAAALRGALSDRASCG----------------R-VHVVTNL--ITGDT-------- --PKTKLVV--VDEND--E---LTWRSLRNVPEVH-L---------------LDAGQLNTYDVLVNDD----VVFTREAF EQVVPRLKLRYREEI----VPKLREQFGYKNIMQVPKLTKIKVNMGIG-EAARDSKLIEGAIRDLAAITGQRPAIARARK SIAQFKLREGMPIGAHVTLRGDRMWEFLDRLLSLALPRIRDFRGLSP-KQFDGRGNYTFGLTEQLMFHEVD-----QDKI DRLRGMDITIVTT-----------------------ATDDEQGRALLKLLGFPFMSRIG-R--LPIPVPAGVEVT-I--- -D-G--R-HVQVKGPKGTLSHTV-AEP----IQVSRAEDGS--IQV---TR-P--NDENKVR-ALHGLTRTLIANMVTGV TQGYSKTLEIVGVGY--RVQAKSPTQ--LEFA--LGYSHPIVVDA-P-E-GITFRVE--K-PTLFHVEG-IDKQKVGQVA ANIRKLR------KPDPY---KGKGVRYQGEVIRRKVGK----------MIQQESRLKVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------SVKKGDVVKAVVVRTAKERRRPDGSYIRFDENAAVLIR-DSGD-PRGTRIF GPVGRELR-DKKFMRIISLAPEVLLK-I--HDLRPAPGA-NRPRIRKG-RGEASK--GKTAGRGTKGSKARTT---I--- -RPGF-E-GGQLPLQRRVPKLKG--FSNVNLSQLVTPEDLVAK-GAVRVK---------VLG--NGE-I-S-V-A-LNV- KAHAFSASAKEKIAAAGGSV-K---QHR--PRR---SGMA-KGGTRVVFG----------DYGIQAL--EHAYVTNRQIE AARIAMTRHI------RRGGKVWINIFPDRPLTKKPAETRMGSGK---------GSPEWWIANVKP-GRVMFEL--SG-- VPEPVAREALRRAMHKLPMKCRF-VRVVARARRHRRVRKKI---FGTAERPRLVVTRSTRHMFVQIVDD---T--KGHTL VSASTM-DASL-RG------LEG-TKTEKARKVGELLAQR--AKAAG-ITQVVFDRGGNRYA--GRIAALADSAREGGLV F--------------------------------------------------------------ME-ARAQVRFARHTPRK ARRVVDLIRGLPASEAQAVLKFA---------------------------------PQAASKTVYKVLQSAIAN----A- EHNF-KLDKDTLWVSRAWVDEGPTLKRFRPRAQGRAYRINKRTSHITVIVESKLHVKKGDLVQVIAGK------DK-GAK GRVIRALPREQ--RVV--VEGVNLIKKHSKVTHQGP--RG-AKE-GGVLTMEAPIHVSNVK-KLKDDE-----KAEK--P ------EKK---AA----------KGD---TTEATG---EDK--MGQKVHPHGFRLG--IT-TDFKSRWYA------E-K L--YKDYVAEDVAIRRML--QKGME-----RAGISRVEIERTT-D-RVQVDIHTARPGIVIGRRGAEADRIRGDLEKLVQ LNILEVKN---PEIDAQLVAQGVAEQLSSRVSFRRAMRKAMQTAMKS-GAKGIRIQCSGRLGGAEMSRSEFYREGRVPL- -HTLRADIDYGFYEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANAAYHDTVSM-PYSKIKAHIAEILQQEGYIQSWS VED----A---K----VGKNLVIELKFG---PNR-------E---RALAGLRRVSKPGLRVYAKKDNLPRVLGGLGIAIL STSSGLMTDKQARKRGVGGEVLAYVWMAGQKIRIRLKAYDHEVIDSSAKKIVETVTRTGAKVAGPVPLPTEKNVYCVIRS PHKYKDSR-EHFVMRTHKRLIDIIDPTPKTVDSLMRLDLPAGVDISIKLRKTREGIVVSDKMDKTVVVAVEDRVKHPLYG KVIRRTSKYKAHDEH--NACGVGDRVLLMETRPLSATKRWRVVRIIEKA------------------------------- -MPRSL-KKGPFVDD-HLMKKVIAQNE---KGTKN----VIKTWSRRSMIVPEMIGHTIAVHDGRKHVPVFITE-AMIGH KLGEFAPTRTFRSHV------K--EDR----RSR-------R >ACTINO_Tropheryma_whipplei_str_Twist Concatenation of 2 sequences MAVRKSNPLTPARRGMSFSDFAE-ITRA------------TP-HKSLLSKLSKTGGRNNHGRITARH-IGGGHKRR---- YRLVDFR-RS-DK-DGVKAKVAHIEYDPNRTARIALLHFL-DGAKRYILAPSGLKQGDVVESGS-S-AD-IRPGNSLCIR DIPVGTILHAVELRPGQGAKLARSAGSSVRLSAK--DGDFAILKLPSGEIRMVSLSCRATIGEVGNGQRLNVSLGKAGRS -RWC-----GVR-P-SVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGRPEG--KTR-RANKPSD-R-FIIRRK --------------------------------MAR---A-LLGTKVGMTQIW--SGRR---------VVPVTAVAVTTNV VSQVK----APE----K--DGY--SRLQIAT-------GA--IVNR----------PRKGHFK----------------- ---AG-LTPRRFIREVDS----------EGSL----------GD-EFGP--E-I-FQEGQLVDVVGKSKGKGFSGTMKRH NFQG-VSATHGSHRNHRK-PGSVGAS-STPS-RVFKGTRMAGRLGSSRVTVHNLRLVKIDSENG---------------- ----------LLLVEGA-VPGSSGSPVIIRMSPSATVFD-IGGNAV-GTLQLVGHLF----DS-DP-NLHLIHQVVVAQQ AAFRQGTHKTKSRAE--------VS-GSGRKPF---------RQKGTGNAR--------CGS---TR-AP----QM---- RGGGVVHGPV-P-RNYVHRTPKKMIKAALAGCLTNRARAG----------------R-VHIVDSF-----GD-T------ --PSVALVV--AQASD--S---VAYRSVRNIPGVR-L---------------VHVGQLNSYDVLRSDD----VLFTRGAY NVFVPRLLTRYREEI----VPVLMSRFDINNVHQVPSITKIVVNSGVG-DAARDSKIIEGAVSDITLITGQKPRINRAKQ SIAKFKLREGQAVGVTATLRGRRMWEFLDRLLTLALPRIRDFRGISD-KQFDGHGNYTFGLSEQGIFHEID-----QDKI DRVRGMDITVVTT-----------------------SSSDDMARALLGELGFPFMSRVG-K--LPIEIPVGVEVC-V--- -N-G--R-TVSITGPKGSLYLDI-AEQ----IGVSVSD-GK--VLV---SR-S--DDSRTAR-ALHGLTRALIANNVHGV LHGYTKTLEIVGTGY--RVSKKG-EN--LELA--LGFSHPVFVDPVP---GVSFGVE--G-NSKIIVSG-IDKQAVGEAA ASIRKLS------KPEPY---KGKGIRYSDEIVRRKVGK----------MIQQESRLKVADNTGAKSLSVIRVLG-SNRR F--GSLGDVVVASVKDAVPGSS-------AVKKGDVVKAVIVRSTKEVRRTDGSYIRFDDNAAVILR-PDND-PRGTRIF GPVARELR-DRKFTRIISLAPEVVIK-L--HHLRPAPGS-RRARVRVG-RGEGSK--GKTAGRGTKGTKARAP---V--- -RPGF-A-GGQIPLHMSIPKLKG--FKNISIKRLVTRDNVMSV--IGKVK---------LLS--DGE-V-T-V-K-FDI- TVDKASAAAVEKITSAAGTVMK---QHR--PNR---KGMS-GCGTRIVFG----------DYGIQAL--SRAYVTNRQVE SARIAMTRHI------RRGGRVWINIYPDRPLTKKPAETRMGSGK---------GSPEYWVANIRP-GRIMFEV--SG-- VSESLAKEALMRAIHKLPLRARI-VRASARKRRHVRLRKKI---SGTCDRPRLSVTRSNRHVFVQAVDD---I--SGKTL VSASTM-EKDI-RA------LEL-GKTERALAVGKLVAQR--ALAVG-VKSAVFDRGGCKYT--GRVAAVAEGAREAGLQ T-------------------------------------------------------------PLE-AFASLKHSGVTPQK VRRIVDLIRGRSVDEALAILRFS---------------------------------PHSASGILYKLIVSAQAN----Y- ANLL-GRD-DDLFVSSVYVDEGKTYKRGRPRARGSSSRILKRGSHVTVTLSKSVKIRKGDLVQVITGSKTGG--KK-GKQ GRVLAV--SGD--RVW--VEGVNLTTRHRK-RVTND--KG-TSS-GGLEKRESPMHISNVA-LVDPET-------GA--P --TKVGFLV---KT--------SGRVR---FAKKSG---KEL--MGQKINPYGLRLG--IT-TDHVSHWYS-DSTRPG-Q R--YADYVSEDIKIRSYL--TKTLD-----RAGIARIEIERTR-D-RIRVDIYTARPGIVIGRRGAEADRYRLELEKIVQ LNILEVKN---PETTARLVAQGIAEQLAARVAFRRAMRKGLQSATSA-GVRGIRIRLAGRLGGAEISRSEFYIEGQVPL- -QTLRASIDYGFYEARTPYGHIGVKVWIYMTMTDPLSDMFSRIRNANQVLHKKVTV-PSSRLKVSIADLLKREGYILDYS VID----E---H----PGQLLVIELKYG---PDK-------S---RALVGLKRVSKPGLRVYAKSSNLPEVFGGLGIAIL STSSGLLTCSQARKKGVGGEVLAYAWMEEQKIRIRLKSYSHEIIDVSAKKIVDTVTRAGATIVGPVPLPTKKSVVCVIRS PHRHKDSR-EHFEMRTHKRLINVVDLTPRAVDALMRLDLSSEVNVEIKLRKSRRGYVTSNSMDKTIVVKIEDRVKHALYG KVIRKTSKVKAHDQG--SIAGVGDLVLISETRPISATKRWRLVQILEKAVLGVDPKVKPAEPISRAIVLLFVVNPGSVGK LVPRSL-KKGPFVDM-HLLKKVRAGNE---SKDRN----MIKTWSRRSMIIPEMLGHTIAVHDGRRHIPVFITE-SMVGH KLGEFAPTRTYRGHV------K--DDR----KAR------RR >ACTINO_Tropheryma_whipplei_TW08/27 Concatenation of 2 sequences MAVRKSNPLTPARRGMSFSDFAE-ITRA------------TP-HKSLLSKLSKTGGRNNHGRITARH-IGGGHKRR---- YRLVDFR-RS-DK-DGVKAKVAHIEYDPNRTARIALLHFL-DGAKRYILAPSGLKQGDVVESGS-S-AD-IRPGNSLCIR DIPVGTILHAVELRPGQGAKLARSAGSSVRLSAK--DGDFAILKLPSGEIRMVSLSCRATIGEVGNGQRLNVSLGKAGRS -RWC-----GVR-P-SVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGRPEG--KTR-RANKPSD-R-FIIRRK --------------------------------MAR---A-LLGTKVGMTQIW--SGRR---------VVPVTAVAVTTNV VSQVK----APE----K--DGY--SRLQIAT-------GA--IVNR----------PRKGHFK----------------- ---AG-LTPRRFIREVDS----------EGSL----------GD-EFGP--E-I-FQEGQLVDVVGKSKGKGFSGTMKRH NFQG-VSATHGSHRNHRK-PGSVGAS-STPS-RVFKGTRMAGRLGSSRVTVHNLRLVKIDSENG---------------- ----------LLLVEGA-VPGSSGSPVIIRMSPSATVFD-IGGNAV-GTLQLVGHLF----DS-DP-NLHLIHQVVVAQQ AAFRQGTHKTKSRAE--------VS-GSGRKPF---------RQKGTGNAR--------CGS---TR-AP----QM---- RGGGVVHGPV-P-RSYVHRTPKKMIKAALAGCLTNRARAG----------------R-VHIVDSF-----GD-T------ --PSVALVV--AQASD--S---VAYRSVRNIPGVR-L---------------VHVGQLNSYDVLRSDD----VLFTRGAY NVFVPRLLTRYREEI----VPVLMSRFDINNVHQVPSITKIVVNSGVG-DAARDSKIIEGAVSDITLITGQKPRINRAKQ SIAKFKLREGQAVGVTATLRGRRMWEFLDRLLTLALPRIRDFRGISD-KQFDGHGNYTFGLSEQGIFHEID-----QDKI DRVRGMDITVVTT-----------------------SSSDDMARALLGELGFPFMSRVG-K--LPIEIPVGVEVC-V--- -N-G--R-TVSITGPKGSLYLDI--AE-Q--IGVSVSD-GK--VLV---SR-S--DDSRTAR-ALHGLTRALIANNVHGV LHGYTKTLEIVGTGY--RVSKKG-EN--LELA--LGFSHPVFVDPVP---GVSFGVE--G-NSKIIVSG-IDKQAVGEAA ASIRKLS------KPEPY---KGKGIRYSDEIVRRKVGK----------MIQQESRLKVADNTGAKSLSVIRVLG-SNRR F--GSLGDVVVASVKDAVPGSS-------AVKKGDVVKAVIVRSTKEVRRTDGSYIRFDDNAAVILR-PDND-PRGTRIF GPVARELR-DRKFTRIISLAPEVVIK-L--HHLRPAPGS-RRARIRVG-RGEGSK--GKTAGRGTKGTKARAP---V--- -RPGF-A-GGQIPLHMSIPKLKG--FKNISIKRLVTRDNVMSVIGKKRVK---------LLS--DGE-V-T-V-K-FDI- TVDKASAAAVEKITSAAGTVMK---QHR--PNR---KGMS-GCGTRIVFG----------DYGIQAL--SRAYVTNRQVE SARIAMTRHI------RRGGRVWINIYPDRPLTKKPAETRMGSGK---------GSPEYWVANIRP-GRIMFEV--SG-- VSESLAKEALMRAIHKLPLRARI-VRASARKRRHVRLRKKI---SGTCDRPRLSVTRSNRHVFVQAVDD---I--SGKTL VSASTM-EKDI-RA------LEL-GKTERALAVGKLVAQR--ALAVG-VKSAVFDRGGCKYT--GRVAAVAEGAREAGLQ T-------------------------------------------------------------PLE-AFASLKHSGVTPQK VRRIVDLIRGRSVDEALAILRFS---------------------------------PHSASGILYKLIVSAQAN----Y- ANLL-GRD-DDLFVSSVYVDEGKTYKRGRPRARGSSSRILKRGSHVTVTLSKSVKIRKGDLVQVITGSKTGG--KK-GKQ GRVLAV--SGD--RVW--VEGVNLTTRHRK-RVTND--KG-TSS-GGLEKRESPMHISNVA-LVDPET-------GA--P --TKVGFLV---KT--------SGRVR---FAKKSG---KEL--MGQKINPYGLRLG--IT-TDHVSHWYS-DSTRPG-Q R--YADYVSEDIKIRSYL--TKTLD-----RAGIARIEIERTR-D-RIRVDIYTARPGIVIGRRGAEADRYRLELEKIVQ LNILEVKN---PETTARLVAQGIAEQLAARVAFRRAMRKGLQSATSA-GVRGIRIRLAGRLGGAEISRSEFYIEGQVPL- -QTLRASIDYGFYEARTPYGHIGVKVWIYMTMTDPLSDMFSRIRNANQVLHKKVTV-PSSRLKVSIADLLKREGYILDYS VID----E---H----PGQLLVIELKYG---PDK-------S---RALVGLKRVSKPGLRVYAKSSNLPEVFGGLGIAIL STSSGLLTCSQARKKGVGGEVLAYAWMEEQKIRIRLKSYSHEIIDVSAKKIVDTVTRAGATIVGPVPLPTKKSVVCVIRS PHRHKDSR-EHFEMRTHKRLINVVDLTPRAVDALMRLDLSSEVNVEIKLRKSRRGYVTSNSMDKTIVVKIEDRVKHALYG KVIRKTSKVKAHDQG--SIAGVGDLVLISETRPISATKRWRLVQILEKA------------------------------- -MPRSL-KKGPFVDM-HLLKKVRAGNE---SKDRN----MIKTWSRRSMIIPEMLGHTIAVHDGRRHIPVFITE-SMVGH KLGEFAPTRTYRGHV------K--DDR----KAR------RR >ACTINO_Xylanimonas_cellulosilytica_XIL07,_DSM_15894 Concatenation of 2 sequences MGIRKYKPTTPGRRGSSVADFVE-VTRS------------QP-EKSLVRPLSKTGGRNNTGRITTRH-KGGGHKRQ---- YRVIDFR-RH-DK-DGVPAKVAHIEYDPNRTARIALLHYA-DGEKRYIIAPNKLSQGDVVEAGA-G-AD-IKPGNNLPLR NIPTGTVIHAIELRPGGGAKIARSAGVSVQLVAK--DGPYAQLRMPSGEIRNVDLRCRATVGEVGNAEQSNINWGKAGRM -RWK-----GVR-P-TVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQPEG--RTR-RPNKSSD-K-LIVRRR --------------------------------LQKNVTA-VLGKKLGMTQLWD-EAGR---------LVPVTVVAVDTNV VTQVR----TTE----T--DGY--SAVQLAV-------GQ--IVTQ----------PLKGHFK----------------- ---AG-VTPRRHVAEIRT--------ADASTY-----TV---GQ-EITA----AAFEAGAVVDVSGTTKGKGTAGVMKRH GFAG-VGASHGSHRNHRK-PGSIGGA-STPS-RVFKGLRMAGRMGNARQTTQNLTVHAVDAEKG---------------- ----------LLLVKGA-VPGPKGGVVVVKTSLTVDVLD-AQGKKA-GQAELPAEVF----DV-VT-NVPLIHQVVVAQR AAARQGTHATKTRGE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---TR-AP----QF---- AGGGTVHGPQ-P-RSYDQRTPKKMKAAALRGALSDRARAG----------------R-VHVVTGF--GIDGT-------- --PSTKLVV--TERSD--E---ATILSLRNVPTVH-L---------------LVADQLNTYDVLVSDD----VVFTQGAL AAFLPRLKQKYREEI----LVALREEFGYPNVTLVPGLTKIVVNMGVG-DAAKDSKLIEGAIRDLTAITGQKPQVTKARK SIAQFKLREGMPIGAHVTLRGDRMWEFLDRLLSIALPRIRDFRGLSP-KQFDGHGNYTFGLTEQSMFHEID-----QDKI DRVRGMDITVVTT-----------------------ANTDDEGRSLLRRLGFPFMSRIG-K--IPVPVPAGVDVT-I--- -S-G--A-LVTVKGPKGTLEHAV-PAP----ITVAQED-AT--LVV---SR-P--NDERESR-ALHGLTRTLLANIVTGV TQGYEKKLEIVGTGY--RVTAKG-SD--LEFA--LGFSHPVIVSA-P-E-GITFSVE--G-PTKFTVAG-ISKQQVGEVA ANIRKIR------KPEPY---KGKGVRYAGEVVRRKVGK----------MIQQESRLRVADNTGAKEILCIRVLG-SGRR Y--AGIGDVIVATVKDAIPG-G-------NVKKGDVVKAVIVRTAKERRRPDGSYIKFDENAAVILK-NDGE-PRGTRIF GPVGRELR-DKKFMKIISLAPEVLLK-V--HHLRPAPGA-KTAKTRVG-RGEGSK--GKTAGRGTKGTKARYQ---V--- -PQRF-E-GGQMPLHMRLPKLRG--FKNVNLDKLVTVEDLVAK-GAVRVK---------VLG--TGE-I-T-V-K-LDV- AVDALSGSAKDKILGAGGSV-K---QHH--PGR---SGAS-KGGNTISFG----------EFGIQAL--EPAYVTNRQIE AARIAMTRHI------KRGGKVWINIYPDRPLTKKPAETRMGSGK---------GSPEWWVANVKP-GRILFEL--AG-- VPEPLAREAMRRAIHKLPMKCRF-VKAVAKQRRHLRLRKKI---SGTAARPRLVVTRSNRHMVAQVVDD---T--VGKTV ASASTL-EADL-RAFD------G-DKVAKARKVGELVAAR--AKSAG-VESVVFDRGGNKYH--GRVAAVADGARDAGLA L--------------------------------------------------------------ME-AKAQARFVRVTPMK ARRVVDLIRGKQAGEAVAVLKFA---------------------------------PQAAAEPVRKVVESAIANARVKA- DRASERFDEQELVVAAAFVDEGPTLKRFRPRAQGRAAQVLKRTSHITVVVAPMANIKKGDQVIVIAG----R--DK-GKT GRVLEVLKDSD--RLV--VEGIQRVTKHVK-AGQTS--RG-TRT-GGIETVEAPIHVSNVM-LVDPES-------KK--G --TRVGVRL---EQ--VER---DGRVR---VAKRSG---KDI--MGQKVHPHGYRLG--IT-TDHRSRWFA-DSTKPG-Q R--YRDYVREDVEIRKLM--ATGLE-----RAGIAKVEIERTR-D-RVRVDIHTARPGIVIGRRGAEADRIRGELEKLVQ LNILEVKN---AEIEAQLVAQGIAEQLASRVSFRRAMRKGIQSAQRA-GAKGIRVQVAGRLGGAEMSRSEFYREGRVPL- -HTLRANIDYGFYEARTTFGRIGVKVWIYMTMTDPIADMLTRLRNANSAHHDTVTM-PSSKLKLHIAEILQKEGYITGFV VED----A---K----VGKNLTITLKYG---QNR-------E---RALSGIRRVSKPGLRKYAKSTELPKVLGGLGVAIL STSSGLLTDRQAQAKGVGGEVLAYVWMAGQKIRIRLKSYDHEVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVFVVIRS PHKYKDSR-EHFEMRTHKRLIDIIDPTPKAVDSLMRIDLPADVNIEIKLRKTRRGYVVSDKMDKTIVVEVEDRVKHPLYG KVMRRTTKVKAHDEQ--NSAGTGDLVVIMETRPLSATKRWRLVEILEKA------------------------------- -MPRSL-KKGPFVDG-HLQKKVDVQNE---KGTKN----VIKTWSRRSVITPDFLGHTFAVHDGRKHTPVFVTE-SMVGH KLGEFAPTRTFRGHV------K--DDK----KGR------RR >ALPHA_Acidiphilium_cryptum_JF-5 Concatenation of 2 sequences MALKHFKPVTASLRGTVLVDRSE-LWKG------------KP-VKGLTEGLTSSGGRNNHGRTTVRF-RGGGHKRA---- YRVVDFK-R--RK-FDVAATVERLEYDPNRSAFLALVKYE-DGELAYILAPQRLKVGDQVVAGV-K-VD-VKPGNAMPLS AIPVGTIVHNIELKAGAGGKLARSAGTFAQLVGK--DQGYAQVKLMSGELRLIRGECMASIGAVSNPDHSNQQLGKAGRK -RWL-----GRR-P-HNRGVAMNPVDHPLGGGEGRT----SGGRNPVTP---WGKPTKGAKTR-ANKRTDG---LIIRRR --------------------------------MSVMRTG-IIAKKLGMTRLFR-EDGT---------HVPVTVLHMDDVR VVAAR----TKE----R--DGY--AAVQLGF-------GH--AVTK----------PMKGHF------------------ ---AAKVEPANRLVEFRV--------ADDAVL-----EA---GQ-VLSA--A-H-FTVGQKVDVAGISKGKGFAGGMKRW NFRG-LEASHGVSISHRS-LGSTGNR-QDPG-KTFKNKKMAGHLGGERITTLNLEVAAIDEARN---------------- ----------LIMIKGA-VPGAKDGYVLVR--MQIDIST-LDAGSA-GKAELPEEYF----AA-TP-RADIMARVVHWQL AKRRAGTHKVKGMGE--------VS-GTTKKPY---------RQKGTGNAR--------QGS---LR-AP----QF---- RTGGAVHGPV-V-RDHGYSLNKKVRRLGLISALSQKLAEG----------------K-LVVLDTV---AGV--------- --SKTSLVV--DAVVD--E---GFARASRNLIGID-V---------------LPVVGANVYDILQHDT----LAITAAGL EGLKTRLQQHYETVV----REALQKEFGYTNPMQVPKLEKIVINMGVG-EAAADQKKLDAAVAELTLIAGQKPVKTVAKK AIAGFKIRKGLPIGCKVTLRRARMYEFLDRLVTIALPRVRDFRGISG-KGFDGRGNFAMGLKEQIVFPEIE-----YDKV DDMRGMDIVFVTT-----------------------APTDAEAKALLKGFEIPFMSRVG-K--YPVALPQGVSIT-V--- -V-D--G-ILTAKGKLGELKMPL--SE-R--VETVVED-GK--VTV----S-P--RDKAASR-MMWGTTRANVANMVQGV SQGYAKTLEINGTGF--RAAVQG-SN--LVMN--LGFSHDVVYPV-P-Q-GIKITCE--K-PTSIKVEG-IDKRLVGQVC AELRAFR------PPEPY---KGKGVKFEGEAIRRKEGK----------MIIVESNLDVADNSGARRVQCIKVLG-SKRR T--ASVGDVIVVSIKDAIPR-G-------KVKKGDVHQAVVVRTAYPVRRADGSVIRFDRNAAVLIN-KQME-PIGTRIF GPVTRELR-ARKFMKIISLAPEVLMK-L--NELRDNPGA-RPKSKRLG-RGIGSGK-GKTSGKGVKGQKAREGVS----- -LNGF-E-GGQLPIYRRLPK-RG--FNNLNVGTLITEATLRAA-GVYAVR---------LLG--RGE-I-S-Q-K-VEI- EVSGASASAIAAIEQAGGSV-K---AHK--GRI---HGTA-KGNTQLNFG----------QFGLKAL--EPERITARQIE SARRAITRQM------KRAGRVWIRIFPDLPVSTKPAEVRMGSGK---------GAPEYWVARVQP-GRIMFEI--DG-- VAEGIAREALKLGAAKLPIKTKI-VENEARRRQRLRYQIRL----KAHGRPRLSVFRSGKHIYAQVIDD---A--AGRTL AAASSL-DAGL-RSAL----KTG-ADKAAAAAVGKLVAER--AKEAG-VTQVVFDRGAYMYH--GRVKALAEAARESGLD F-------------------------------------------------------------DSE-AEAVLRNLRCSPRK LNVVAASIRNKPAGKAVADLTFS---------------------------------KRRIAKDVKKALESAIAN----A- ENNH-QLDVDRLVVTTADVGRSIVMRRFHARGRGRAARVEKWFSHLRIVVAEAARIRKGDRVVVIAGA------SK-GRE GEVLRVLPAEN--KAV--VSGVAVAKRHTK----AR--GM-GEQ-GGIIQKEMPVHLSNIA-LIDPET-------KK--P --TRVGFRV---LE--------DGKVR---VARKSD---SVI--MGHKVNPVGLRLG--IN-RTWDSRWFA------G-A D--YASLLHDDLKLREHL--LGRLS-----GAGVSKVLIERPA-K-KPRVTIYAARPGVVIGKKGQDIEVLKKELSSMVS LNIVEIRK---PEIDAALVAQNIAQQLERRVAFRRAMKRAVQSAMRL-GAQGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDFGVATAKTTYGTCGVKVWIF--MSDPLGDMLTRIRNAQRARHAVCVA-PASNLRANVLDVLKREGFIRGFS KEE--LRP--------GVAQLRIELKYN----DG-------E---PVIKEITRVSRPGRRVYSKIKELPRVYAGLGVSIL STPRGVMSDVEARTANVGGEVLCRVFMDSQNIRIRLKAYDHRVLDNSTREIVNTAKRTGAQVRGPIPLPTHIERFTVNRS PHVDKKSR-EQFEIRTHRRLLDIVEPTPQTVDALMKLDLAAGVDVEIKIKRVLTGRVVSDKMDKTVTVLVERRVMHPLYK KFIRRSKKYAAHDEG--NVCAMGDLVRIEECPPISKRKAWLVTARNGAA------------------------------- -MTRSV-WKGPFVDG-YMLNKADASRA---SGRNE----IIKIWSRRSTILPQFVGLTFGVYNGRKFLPVQVTE-NMVGH KFGEFSPTRTFNGHA------A---DK----KAK------RG >ALPHA_Agrobacterium_radiobacter_K84 Concatenation of 2 sequences MALKTFNPTTPSQRQLVIVDRSS-LYKG------------KP-VKSLTEGLSSKGGRNNTGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEATVERIEYDPNRTAYIALVKYA-DGDQAYILAPQRLAAGDKVIASEKA-VD-VKPGNTMPLQ FIPVGSIIHNVEMKPGKGGQIARSAGGYAQLVGR--DQGMAILRLNSGEQRLVHGTCLATIGAVSNPDHGNINDGKAGRS -RWR-----GKK-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-MIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HVPVTVLRMEGCQ VVAQR----TVE----K--NGY--TAVQLGA-------GQ--ATSK----------ALRGHFV----------------- ---AS-VEPKAKLVEFRV--------SDDNLL-----EV---GT-EIKA--A-H-FSAGQLVDVTGTTIGKGFAGAMKRH GFGG-LRATHGVSVSHRS-HGSTGSR-QDPG-KVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGAWIIVR--MELNVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDIIARVIRWQL AKKRQGTHKAQGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKKVRALGLRLALSAKLKAE----------------D-VIILDNL----VAA-D------ --AKTKLFI--GAELD--S---NFKLAAANIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRLKKEYVARI----RAALQEKFSYANEMQIPKLDKIVINMGVG-EATADSKKPTVAAADLAAIAGQKPVITHARN SIAGFKVRENMPIGAKVTLRGARMYEFLDRLVNIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATTDDEARALLKEFNFPFMSRIG-K--KPVQVPAGITAS-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--IGLKLED-NA--IVV----T-P-LSNSKDAR-SKWGMSRTMIENILKGV KEGYERKLEINGVGY--RAALQG-KN--LQLA--LGFSHDVVYEP-P-E-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDVIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVL---M--NEIKDNEGS-THSRKRLG-RGIGSGS-GKTGGRGVKGQKSRSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLARIIDAAALKAA-GVIRVR---------VLS--DGE-L-K-A-K-ISL- EVAGASKPAVEKIEKAGGSI-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKSQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEEIAREALRLGAAKLSVKTRF-VRKEALARRANRVRRQL--KSVANGRPRLSVHRSSKNIYVQVIDD---A--AGKTL ASASTL-DKDL-RGSL----KTG-ADTAAAALVGKLVAER--ATKAG-VKEVVFDRGAFIYH--GRIKALAEAAREGGLS F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVAASIRGKKVDRALAELEFS---------------------------------RKRIAGAVKKTLESAIAN----A- ENNH-DLDVDSLVVAEAYVGKSIVMKRFHARGRGRASRIERPFAHLTIVVREMQKIRKGDKVVVLAGK------DK-GRT GEVIQVMPKED--RAV--VRGVNVIKRHQR----QT--QT--QE-AGIISKEASLHLSNLA-IVDKD--------GK--P --TRVGFKV----V--------EGKVR---VAKTSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKMRKFV--MDELK-----QAGISKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIDKLRKKLSDMTH LNIVEVRK---PEIDAVLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCGGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGASRRKSSVST-PASKLRARVLDVLQAEGYIRGYS VVD--FGN--------GKSELSIELKYY----EG-------S---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGIIIL STPKGVMADHQAREQNVGGEVLCSVF------------------------------------------------------ -------------------------------------------------KRILQGVVVSDKNEKTVVVRVERRFAHPLLQ KTVRRSKKYKAHDEN--NQYKVGDTVSIEECAPISKDKTWTVVS--AQS------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRSE----VIKIWSRRSTIMPQFVGLTFGVYNGSKHIPVSVNE-DMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Agrobacterium_tumefaciens_C58_(Cereon) Concatenation of 2 sequences MALKSFNPTTPSQRQLVIVDRAS-LYKG------------KP-VKALTQGLSSKGGRNNQGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEGTVERLEYDPNRTAFIALVTYT-DGEQAYILAPQRLAAGDKVIASDKA-VD-VKPGNTMPLQ YIPVGSIIHNVEMKPGKGGQIARSAGTYVQLVGR--DAGMAILRLNSGEQRLVHGSCLASIGAVSNSDHGNINDGKAGRS -RWR-----GKR-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-FIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HIPVTVLRLDNVQ VVAQR----TED----K--NGY--TAVQLGA-------GQ--STTK----------ALRGHF------------------ ---AANVEPKAKLVEFRV--------SPENLI-----DI---GA-TLTA--N-H-FQSGQLVDVTGTTIGKGFAGAMKRH NFGG-GRASHGNSVSHRA-HGSTGNN-QDPG-RVWKGKRMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGSWIIVR--MELNVKT-LEGKDA-GKVSLSDEIF----GL-DP-RQDILARMVRWQL AKKQQGTHKTKNRSE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHDLPKKVRALALRHALSAKLKAE----------------E-LIIVDQL----VAS-E------ --AKTKLVI--GAELD--G---NFKLAAQNIPNVD-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRLKTEYVSRI----RGAMQEKFSYANVMMIPKLDKIVINMGVG-EATADSKKPTIAAGDLAAIAGQKPVITKARN SIAGFKVREHMPIGAKVTLRGERMYEFLDRLINIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATSDDEARALLTEFNFPF-----------------MTAN-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-D--IQLKLED-NG--VSV----T-P--ANGKEAR-SKWGMSRTMIENIFKGV KDGYERKLEINGVGY--RAALQG-KN--LQLA--LGFSHDVVYEP-P-V-GITIAVP--K-PTEIIVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAEERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVL----------------------------------------MKGQKARSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLGRIIDAAALKAA-GVIRVR---------ILA--DGE-L-T-S-K-VAF- EVAGASKPALEKIEKAGSSI-K---QFK--GRI---KGVA-KGGFDLAFG----------EFGLKSQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VTEEIAREALRLGAAKLSVKTRF-VRKEALARRASRVRRQI--KAVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTL ASASTL-EADL-RSSL----KTG-ADVAAAAVVGKLVAER--GVKAG-VKDVVFDRGAFIYH--GRIKAVAEAAREGGLN F-------------------------------------------------------------DNE-AQAIARTLRVSPQK LNLVAALIRGKKVDRALAELEFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALVVAEAYVGKSITMKRFHARGRGRASRIEKPFAHLTIVVREMQKIRKGDNVVVLTGK------DK-GRT GEVIQVMPKED--RAV--VRGVNMVKRHQR----QT--QA--QE-AGIINKEASLHISNIA-IVDKD--------GK--P --TRVGFSV----V--------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWYA------DTA E--YGKLLHEDLKIRAYL--IKELK-----QAGIAKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRKKLSEMTH LNIVEVRK---PEIDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCGGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGAARRKSSVST-PASSLRARVLDVLQSEGYIRGYS KVD---FE---N----GKAEFTIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVF------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -MARSV-WKGPFVDG-YLLTKAEKVRE---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGSKHVPVSVNE-DMVGH KFGEFSPTRTYYGHG------A---DK----KAK------RK >ALPHA_Agrobacterium_tumefaciens_C58_(Dupont) Concatenation of 2 sequences MALKSFNPTTPSQRQLVIVDRAS-LYKG------------KP-VKALTQGLSSKGGRNNQGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEGTVERLEYDPNRTAFIALVTYT-DGEQAYILAPQRLAAGDKVIASDKA-VD-VKPGNTMPLQ YIPVGSIIHNVEMKPGKGGQIARSAGTYVQLVGR--DAGMAILRLNSGEQRLVHGSCLASIGAVSNSDHGNINDGKAGRS -RWR-----GKR-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-FIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HIPVTVLRLDNVQ VVAQR----TED----K--NGY--TAVQLGA-------GQ--STTK----------ALRGHF------------------ ---AANVEPKAKLVEFRV--------SPENLI-----DI---GA-TLTA--N-H-FQSGQLVDVTGTTIGKGFAGAMKRH NFGG-GRASHGNSVSHRA-HGSTGNN-QDPG-RVWKGKRMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGSWIIVR--MELNVKT-LEGKDA-GKVSLSDEIF----GL-DP-RQDILARMVRWQL AKKQQGTHKTKNRSE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHDLPKKVRALALRHALSAKLKAE----------------E-LIIVDQL----VAS-E------ --AKTKLVI--GAELD--G---NFKLAAQNIPNVD-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRLKTEYVSRI----RGAMQEKFSYANVMMIPKLDKIVINMGVG-EATADSKKPTIAAGDLAAIAGQKPVITKARN SIAGFKVREHMPIGAKVTLRGERMYEFLDRLINIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATSDDEARALLTEFNFPFMSRIG-K--KPVPVPAGVTAN-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-D--IQLKLED-NG--VSV----T-P--ANGKEAR-SKWGMSRTMIENIFKGV KDGYERKLEINGVGY--RAALQG-KN--LQLA--LGFSHDVVYEP-P-V-GITIAVP--K-PTEIIVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAEERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIRDNEGS-SKDRIRVG-RGIGSGK-GKTGGRGVKGQKARSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLGRIIDAAALKAA-GVIRVR---------ILA--DGE-L-T-S-K-VAF- EVAGASKPALEKIEKAGSSI-K---QFK--GRI---KGVA-KGGFDLAFG----------EFGLKSQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VTEEIAREALRLGAAKLSVKTRF-VRKEALARRASRVRRQI--KAVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTL ASASTL-EADL-RSSL----KTG-ADVAAAAVVGKLVAER--GVKAG-VKDVVFDRGAFIYH--GRIKAVAEAAREGGLN F-------------------------------------------------------------DNE-AQAIARTLRVSPQK LNLVAALIRGKKVDRALAELEFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALVVAEAYVGKSITMKRFHARGRGRASRIEKPFAHLTIVVREMQKIRKGDNVVVLTGK------DK-GRT GEVIQVMPKED--RAV--VRGVNMVKRHQR----QT--QA--QE-AGIINKEASLHISNIA-IVDKD--------GK--P --TRVGFSV----V--------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWYA------DTA E--YGKLLHEDLKIRAYL--IKELK-----QAGIAKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRKKLSEMTH LNIVEVRK---PEIDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCGGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGAARRKSSVST-PASSLRARVLDVLQSEGYIRGYS KVD---FE---N----GKAEFTIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMTGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVSDKNEKTVVVRVERRFAHPLMQ KTVRRSKKYKAHDEN--NQYKVGDVVSIEECAPISKDKRWTVVA--AQA------------------------------- -MARSV-WKGPFVDG-YLLTKAEKVRE---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGSKHVPVSVNE-DMVGH KFGEFSPTRTYYGHG------A---DK----KAK------RK >ALPHA_Agrobacterium_vitis_S4 Concatenation of 2 sequences MALKNFNPTTPSQRQLVIVDRSG-LYKG------------KP-VKSLTEGLSSKGGRNNLGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEGTVERLEYDPNRTAFIALITYA-DGEQAYILAPQRLAAGDKVIASDKA-VD-VKPGNAMPLQ YVPVGSIVHNVELKPGKGGQVARSAGAYVQLVGR--DAGMAILRLSSGEQRLVHGTCLATVGAVSNSDHGNINDGKAGRS -RWR-----GKR-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGKPTKGKRTR-S-NKSTD-K-FIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HVPVTVLRLDNCQ VLAQR----TVD----K--HGY--TAVQLGA-------GQ--ATSK----------AMRGNF------------------ ---AANVEPKAKLVEFRV--------SEDNLM-----DV---GS-ELKA--G-H-FEAGQLVDVTGTTIGKGFAGAMKRH NFGG-LRATHGVSVSHRS-HGSTGSN-QDPG-KVWKGKRMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGSWIIVR--MELNVKT-LEGTDA-GTVSLSDAIF----GL-EP-RQDIIARMVRWQL AKKQQGTHKTKTRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKKVRALALRHALSAKFKAD----------------E-LIIVDQL---VAAD-------- --AKTKLVI---GGV---ELDVNFKLAAANIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRLKAEYVSRI----RQALREQFSYANEMQIPKLDKIVINMGVG-EATADSKKPTVAAADLAAIAGQKPVITRARN SIAGFKVREDMPIGAKVTLRGARMYEFMDRLINIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------APTDDEARALLKEFNFPFMSRIG-K--KPVQVPAGITAS-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--ISVALED-NA--IVV----K-P-VNDSKDAR-SKWGMSRTMIENILKGV KDGYERKLEINGVGY--RASLQG-KN--LQLA--LGFSHDVVYEP-P-Q-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAEERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDNNAAVLID-NKKE-PIGSRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGS-SKDRIRVG-RGIGSGK-GKTGGRGVKGQKARSGVA----- -VNGF-E-GGQMPIYRRLPK-RG--FNNVSLGRIIDAAALKAA-GVIRVR---------VLG--DGE-L-T-T-K-VTI- EVAGASKPAVEKIEKAGGTI-K---QFK--GRI---KGVA-KGGFDLAFG----------EFGLKAL--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEEIAREALRLGSAKLSVKTRF-VRKEALVRRANRVRRQI--KAVANGRPRLSVHRSSKNIYVQVIDD---V--AGRTL AAASTL-DGSL-RSSL----KTG-ADTAAAAAVGKLVAER--AVAAG-VKEVVFDRGAFIYH--GRIKALAEAAREGGLS F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVAALIRGKKVDRALADLTFS---------------------------------RKRIADTVKKTLESAIAN----A- ENNH-DLDVDQLIVAEAYVGKSITMKRFHARGRGRASRIEKPFSHLTIVVREMQKIRKGDKVVVLTGK------DK-GRS GEVIQVMPKED--RAV--VQGINVVKRHQR----QT--QT--QE-AGIINKEASVHLSNLA-IADKD--------GK--P --TRVGFSV----V--------DGKVR---VAKRSG---EVI--MG-------------IN-RTWDSRWFA------DNA E--YGKLLHEDLKIRAYL--MDELK-----QAGIAKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRKKLSEMTH LNIVEVRK---PEVDATLVAQSIAQQLERRIAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGVAEATTAYGICGIKVWIFMTMTDPLGDMLTRIRNGAARRKASVVT-PASKLRARVLDVLQAEGYIRGYS EID----H-GNG-----KAEITIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMNGQNIRIRLKAFDHRVLDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVSDKNEKTVVVRVERRFAHPLLQ KTVRRSKKYKAHDES--NQYKIGDVVSIEECAPISKDKCWTVVS--AQA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---SGRSE----VIKMWTRRSTILPQFVGLTFGVYNGSKHIPVSVNE-DMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Anaplasma_marginale_Florida Concatenation of 2 sequences MSLKVLNPVTPSLRGTVMVNRVA-LWRG------------KP-EKSLVVGRVSSGGRNAHGVITVRH-RGGGHKRL---- HRVVDLK-R--NK-DGVQAVVQRLEYDPNRTAFLALVRYE-DGELSYILAPDGLKVSDVVVSGV-G-SD-VLPGNCLQLG SIPAGTFVHNVELRPCGGGIIARAAGSYAQVMGR--DGAYVLLRLGSGEVRKILALCRATVGVVSNLNNQNIKLGKAGRN -RWL-----GFR-P-TVRGVAMNPVDHPHGGGEGKT----SGGRNSVTP---WGVPTKGKKTR-KRGKHSD-KYKVSSVR --------------------------------SRV---G-LLMKKVGSTAVFG-DAGA---------RVPVTLLLLEDTF VVDVK----SRD----V--HGY--NAVVLGV-----------RLNK----------PQICALK----------------- ---KG-IDVDCHLFESRV--------DTVDGV-----EP---GG-RVLV--D-H-FFQGQFVDVAGRSIGRGFAGVMKRH NFGG-LRASHGVSISHRS-QGSTGQC-QDPG-RVFKGKKMAGHMGHTMSVVQNLRVVLVDSERS---------------- ----------LLVVEGTNVPGPCGSYVLVR--MEVNVVN-IKNEVV-GKVQLSAEVF----GV-QL-RRDVLRDVVTWQL AKRRAGTHKTRCISD--------VS-GTTAKPY---------RQKHTGRAR--------QGS---LR-SP----QF---- RGGAVVFGPV-N-RSHAYSLNKKVRRLGLKVALSMKVSDS----------------K-LVVLDDS----GLE-------- ---KTALVV--AETYE--D---KVMCACRNLPNVD-L---------------LKYAGINVLDILRHDC----VILTVGTV KCLEYMLGSLCKEAV----AQSLMSKLGCSSVMQVPKVVKVCLNMGIG-IGAMDSKVMDSCSRDLALISAQKPVVTRARR SIAGFKIRKGFPIGCMVTLRGKKMYEFLDRLINIALPRERDFKGLSM-SQFDGHGNISFGVKEHISFLEVD-----YDKI DKVRGFDVSVVTT-----------------------AKSDYDAKALLTELGFPFVSRVG-A--MPIEVPEGVKVD-V--- -C-D-GN-SVTVIGKDGTSSSFS-LCH-G--IRAVLDG-ST--LLL----V-N-ERQSPRAK-VMWGSYRSGISNAIKGL SKGFSVELEVNGVGY--RVVCDN-KY--LSMF--VGFSHGVRYVI-P-E-GIEIKCP--K-PTQLVIKG-SDKVKVHMVA ADICSIR------RYDPY---KGKGIFVKGEYVYRKEVS----------MIQKNAILDVADNSGARKVLCIGFLG-KKR- ---ALVGDVIVVSARVVAPR-G-------KVNKGRVYKAVVVRTKGPIRRLDGSTIRFSSNAVVLVN-DQGD-PLGTRVF GPV-RKLP-VGEFTKVMSLAVEVLMK-L--NELFAGLPK-RRRLKVLG-RGLGCGK-GKTSGRGHKGQKARSGCA----- -VNGF-E-GGQQPIFTRLPK-RG--FRSVNIGALISKELMAEL-GMIPVK---------ILG--KGA-L-K-A-K-VGI- SYDAVSKAAWEESLLTEGLSMK---SFK--GRI---KGQT-KGGSELAFG----------SCGLKAL--EPCRLTSKQIE SARRSISRSL------RRVGKVWIRVFCHLPVSKKPVDVRMGKGK---------GSIEMWVCRVQP-GRVLFEI--GG-- VSSVLAREALRKASAKLPMRCSY-IDLKRATRRKRRVRLKL----RSLSSVRLSVFKSNRHFYAQLIDD---E--KGATL AAASTL-EPDV-LATA----KRR-VNSEAARVVARLFAGRLDGLDAN-YRKFVLDRGSCRYI--GVVAAFADELRSLGFE F-------------------------------------------------------------MTTVISARVSGLRSTPSK LNLVADLIRGQDVSTAVMYLKFC---------------------------------RKKAAFLVGKVLKSAVAN----A- RANY-DVDLDSLYVKEVLVGKSFTLRRVRPRARGRACRIRKRYGSVVIRLLK---------MKILR-K---------G-- GHVVA--------K----VAGVALCRKSVK----PSKDRE-----GGIFSVERFIDISNIA-LFDSEA-------GV--R --TKVGYKF----V--------DGKVR---YLKGSG---RVL--MGQKSNPIGLRLG--IV-GTWDSLWYA------G-G G--YASKLHEDLLLRSFV--KKTFH-----HAAVSRVVIARKV-D-AVIINIHSARPGVIIGKKGTDIDRVKQKIAQMVE LHIVEVKK---PDLKAALIAENIAQQLEKRVSFRRAMKRGVQNCLKL-GARGVKVSCSGRLGGAEIARTEWYKEGSVPL- -HTFRANIDYSCAEAKTIYGIVGVKVWVYMSLSDPIADFLTRLRNGQAGMNKVVFV-PHSKVVRSILDILLAEGYIEGFT EES--KSS--------GIKYLKVCLKYY----NC-------A---PVIKKIVRVSRPGKRVYSSADRLPKFYNGLGVYIV STSQGVMLDYRARKLGIGGEILCGVFMVTQKIYIELKAFDHCLLDGSARNIILIARRSGAKVNGPVFFPRRIAKFIVNRS THVDKKSR-EQFEIRTHKRLISLPKANSAILQALMSLQLPAGVDVKVKVKGVLVGVVTDARRDKTVKVSVYRMVHHKVYK KIVKKCRIYSVHDEH--NRCKRGDVVKIREHIPVSATKRWIVVD--S--------------------------------- -MSRSI-KKPPFCAP-HVLRLANRAIA---SNRNA----IINIHSRSSVILHKFIGLTFGVHNGRTYVPVKVTD-NIVGR KFGEFSPTRRFLGHA------G---DK----KVS------RK >ALPHA_Anaplasma_phagocytophilum_HZ Concatenation of 2 sequences MSLRVLNSVTPSLRGTVLVDKTA-LWKG------------RP-EKSLVSSRVSSGGRNSRGVITVRH-RGGGHRRL---- YRVVDFK-R--NK-EGVPAVVKRLEYDPNRTAFLALIQYE-DGELSYILAPSGLKVDDVIMSGA-G-SD-VLPGNCLKLS MIPSGTFVHNVEMKVGGGGIIARAAGSYAQVMGR--DGAYVMLRLGSGEVRRILSVCRATVGVVSNLDNRNIKLGKAGRS -RWL-----GLR-P-KVRGVAMNPVDHPHGGGEGKT----SGGRNSVTP---WGVPTKGKKTR-KRGKHSD-K-YIRVSS ----------------------------------------MWMKKVGSTAMFA-TTGS---------RVPVTLLLLEDTF VVGTK----VSG----I--HGY--DAVVLGT-------K----VNK----------PQVQALK----------------- ---LG-IEEDYKLFESRVK---AVGD-----L-----QP---GS-KVEV--S-H-FFKGQFVDVTGYTIGRGFAGVMKRH NFRG-LRASHGVSISHRS-QGSTGQC-QDPG-RVFKGKKMAGHMGDSKVTMQNLQVMLVDEKES---------------- ----------LLVVRGTGIPGAEGSYVFVR--MEVNIVN-IANEVV-GSIDLNPQVF----GL-EP-RRDVLKEVVNWQL AKRRAGTHKAKGISD--------IS-GTTAKPY---------RQKHTGRAR--------QGS---LR-SP----QF---- RGGAVIFGPV-P-RSHEYSLNKKVRRLGLKVALSMKVAAN----------------K-LVVLDSL----DVD-L------ --KKTALVV--SESCK--E---EVVRACRNLRGVD-L---------------LKCVGINVLDILKHDC----VILTVDTV KSLE-MLGSLSKDAV----AKSLVSRLGKKNVMQVPRVVKVCLNMGIG-ISAADSKVMDSCTRDLAMISAQKPVVTRARK SIAGFKIRKGFPIGCMVTLRGKRMYEFLDRLINIALPRERDFRGLST-SQLDGHGNISFGIKEHISFLEVD-----YDKI DKVRGLDVVIVTT-----------------------ATNDADAKALLLELGFPFMSRVG-A--MPIEIPEGVQVS-V--- ---D-ES-GVTVSDAKGRTSTFS-LSH-G--IKAVLDG-KM--LML----V-N-ENKHTKAK-VMWGSYRSNINNAIRGM ASGFLVEFEVNGVGY--KVVHQG-EC--LSIS--LGFSHSVKYVI-P-E-GIEVKCT--K-PTQFTISG-SDKIKVHMVA ADLCSIR------RYDPY---KGKGIFVKGKYVYRKEVS----------MIQKNAILDVADNSGARKVLCIGFLG-KKS- ---ATVGDVIVVSAKVAAPK-G-------RVTKGKVYKAVIVRVKGPIRRLDGSIIRFSSNAVVLVN-DQGD-PLGTRVF GPV-RKFP-VGEFTKVMSLAVEVLMK-L--NELFSGLPR-LKGRKVLG-RGLGCGK-GKTSGKGHKGQKARSGCT----- -VNGF-E-GGQQSIFTRLPK-RG--FKSVNLGVIISKEMLVNL-GVI-VK---------ILG--KGE-L-G-S-K-VDI- YYDAISRSAESKVSLLGD--MK---SFK--GRI---SGNT-KGGSELAFG----------QCGLKAL--EPCRLTSKQIE SARRSISRSL------RRVGKVWIRVFCHVPVSKKPVDVRMGKGK---------GSTEMWVCKVQP-GRILFEI--GG-- VSVELAREAFRKAQSKLPIKCSF-VDLKRAERRRRRVRLKL----RSLSSIRLSVFKSNRHFYAQLIDD---E--AGRTV AAASTL-ESEV-LAVA----SRR-VNAGAVKIVAKLLAERISGLDAA-YRKFVFDRGSYRYM--GVVAAFADELRSLGFE F-------------------------------------------------------------MSIVIAAKGLGLRSTPAK LNLVADLIRGKDVAVAAMYLKFC---------------------------------KKKAALLIDKVLKSAIAN----A- RANY-GVDADNLYVKEVLVGKAFTLRRVQPRARGRACRISKRYGSVVVKLLEMAKIVSGDDVIVITGS------DK-GKV GKVVKILRKGG--RVLAKVASVALCRKSVK----PS--KN--RE-GGIFSIERFIDISNVA-FFDSEA-------GV--R --TRVGYKF----V--------DGKVR---YLKSSG---RVL--MGQKSNPIGLRLK--IV-GTWDSLWYA------N-R D--YATKLHEDLLLRSFV--KKTFH-----HAAVSKVVIARKV-D-AVIINIHSARPGVIIGKKGVDIDRIKQKIAKMVE LHIVEVKK---PDLKAVLIAENIAQQLEKRVSFRRAMKRGVQNCLKM-GAKGVKVSCAGRLGGAEIARTEWYKEGSVPL- -HTFRANIDYSCVEAKTIYGIVGVKVWVYMSLSDPIADFLTRLRNGQAGMNKVVYV-PCSKVVMAVLRILVEEGYIESFT EEV-RGDS-G-------IKVLKVFLKYF----NS-------A---AAIRKIVRVSRPGKRVYSSADKMPRFYNALGIYIV STSKGIMLDSHARNAGVGGEILCGVFMVTQKIYIELKAFDHGLLDRSARNIVLVAKRSGAKVNGPIFFPRRTAKFIVNRS THVDKKSR-EQFEIRTHKRLISLPKANSAILQALMSLQLPAGVDVKVKVKGVLVGVVTDARRDKTVKVSVYRMVHHKVYK KIVKKCRVYSVHDEQ--NRCARGDVVKIREHVPISATKRWIVVD--E--------------------------------- -MSRSV-KKPPFCAP-HVLRLANRVIA---SNRTS---VVINIHSRSSVILNKFVGLTFGVYNGKTYVPVKVTD-NIVGR KFGEFSPTRRFLGHA------G---DK----KVS------RK >ALPHA_Azorhizobium_caulinodans_ORS_571 Concatenation of 2 sequences MALKHFKPVTPGLRQLVIVDRSG-LYKG------------KP-VKTLTEGKSSSGGRNNNGRITVRF-RGGGHKQT---- YRLVDFK-RA--K-RDVSATVERLEYDPNRTAFIALIKYE-DGELAYILAPQRLAVGDKVIAGE-Q-VD-VKPGNAAPLS NLPVGTIVHNVEMKIGKGGQIARSAGSYAQIVGR--DQGYVIVRLNSGEQRLIHGACYATVGAVSNPDHMNTSLGKAGRS -RWL-----GVK-P-HNRGVTMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGMKTR-S-NKATD-K-FIVTSR --------------------------------DTTMRSG-VIAQKLGMTRIFT-DAGE---------HLPVTVLKVESCQ VVAHR----TLD----K--NGY--VAVQLGA-------GK--RTNK----------AERGQFR----------------- ---AE-VEPKRKLAEFRV--------DADALI-----PV---GA-EITA--D-H-FVVGQYVDVTGTTIGKGFAGGMKRH NFGG-LRASHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGDVTVTTQNLKVVMTDVERG---------------- ----------LIAVEGA-VPGHAGGWIMVR-MMELTVKT-LDGAEA-GSIQLSDAIF----GL-EP-RADILHRMVTWQL ARRQAGTHRTKGRSE--------IN-RTSKKLY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGGRAFGPV-V-RSHAFDLPKKVRALALKHALSSKAKAE----------------Q-IIVLDAA----TLT-D------ --AKTKLVV--DGEQA--T---NFALAARNLASVD-V---------------LPVQGINVYDILRRDT----LVLTRAAV DALEPRLRTHYDSVV----RPKLIEEFGYKNPMQVPVIEKIVINMGVG-EATADTKKVTTAAADLARIAGQKPVLTRARK AISNFKLRENQPVGAKVTLRQARMYEFMDRLITVALPRVRDFRGLNP-KSFDGRGNYAMGMKEHIVFPEIN-----YDQV EQIWGMDIIVCTT-----------------------AKTDDEARALLRAFNFPFMSKIG-K--HPVAIPAGVTAS-V--- -D-G--Q-TVKVKGPKGALEVVL--VE-E--IQASLEG-GE--LKI----A-M--RGEPRHK-SMWGMSRTLVANLVEGV TKGFEKKLEINGVGY--KAAVAG-KN--LQLS--LGYSHDVIYPI-P-E-GIQIAAP--K-PTELVVTG-INKQQVGQVA AEIREFR------GPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AHVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRVDGSVIRFDRNAAVLIN-NNKE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--DEIRDNDGA-RKKRMRVG-RGIGSGK-GKTAGRGVKGQKARTGVA----- -IKGF-E-GGQMPLHRRLPK-RG--FHNVSLGRIVTEAALVAS-GVLRVR---------VLG--SGE-L-K-A-K-VAL- DVAYATKSATEAVEKLGGSV-K---QFK--GRI---HGVA-KGGTELNFG----------EFGLKAL--EPERVTARQIE AARRALTRHM------KRAGRVWIRVFPDVPVTSKPTEVRMGKGK---------GAPEYWAAKVKP-GRIMFEI--DG-- VPVDLAREALTLAAAKLPIKTRF-IDLEALERRKAKVRRAI--RAAANGRPRLSVHRTSKHIYAQIIDD---A--KGETL VAASSL-EKDL-RSSL----KTG-ADVEAAKAIGKLVAER--ATAKG-VTAVVFDRGAYIYH--GRVKALAEGAREGGLQ F-------------------------------------------------------------DNE-AKAVARNLRVSPQK LNLVAGLIRGKKVSTALADLEFS---------------------------------RKRIARDVKKCLESAIAN----A- ENNH-DLDVDDLIVAEAHVGKGLVMKRFSPRARGRASRIEKPFSHITIVVREAAKIKKGDKVVVLAGR------DK-GRT GEVLQVLPKEE--RAL--VRGVNVVKRHQR--------QTAQSE-GGIISKEAPIHLSNIA-VADPKD-------GK--P --TRVGFEV---LD--------DGKVR---VAKRSG---ERI--MGQKVNPVGLRLG--IN-RTWDSRWFA------NKG D--YGTLLHEDIKIRQML--LKQLK-----QAAVSKVVIERPH-K-KCRVTIYSARPGVVIGKKGADIDKLRKKVADMVF INIVEIRK---PEIDARLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGVKVWIFMSINDPIGDLITRIRNAQMRRKDKTST-PGSRLRASLLDVLRDEGYIRGYT TTD----H---G---NGRTEFEIELKYF----DG-------Q---PVIREITRVSKPGRRVYASVKALPRVANGLGIAVL STPQGVMADHDARDKNVGGEVLCTVFMNGQNIRIRLKAFDHRILDASTREIVATAKRTGAQVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVVSDKQDKTVVVRVERRFTHPLLK KTVRRSKKYHAHDEA--NTWSIGDTVWIEEHRPLSKLKNWIVVQGEKRA------------------------------- -MSRSI-WKGPFVDG-YLLKKADAARA---SGRNE----TIKIWSRRSTILPQFVGLTFGVYNGAKHVPVYVSE-DMVGH KFGEFSPTRTYYGHA------A---DK----KSK------RR >ALPHA_Bartonella_bacilliformis_KC583 Concatenation of 2 sequences MALKHFNPTTSGQRQLVIVDRSG-LYKG------------KP-VKTLTEGLLSKGGRNNSGKITARF-QGGRHKRS---- YRFIDFK-R--LK-LDVSAKVERLEYDPNRTAFIALIRYE-DGQLSYILAPQRLDVGDTVVAGL-S-VD-VKPGNAMPLG NMPVGAIVHNVEMKPGKGGQIARSAGAYAQLVGR--DQGMAILRLNSGEQRLVSSNCFATVGAVSNPDHGNINDGKAGRS -RWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGKPTKGKRTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VITQKLGMTSIYN-DTGE---------RVPVTVLRLENCQ VIAQR----TVE----K--NGY--TAVQLGV-------GL--ATSK----------ALRGHF------------------ ---KALVEPKAKIVEFRV--------SSDNLL-----DV---GT-EITV--E-H-FVPGQRVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRA-HGSTGQC-QDPG-KVFKGKKMAGHMGQVRVTTQNVEVVSIDVDRG---------------- ----------LILVRGA-VSGSKGAWVLVR--MDLIIKT-LDGKKT-GELSVSEHVF----GL-VP-REDILQRVVRWQL ARRQKGTHKVQGRSD--------IS-RTGAKMY---------KQKGTGRAR--------HSS---AR-AP----QF---- RGGGKAHGPV-I-RSHAHGLPKKSRALGLRLALSAKFKAN----------------D-LIVIDEF----NLQ-D------ --PKTKLLI--GGKED--V---NFFRAASNIPNID-V---------------LPIQGINVYDILRRSK----LVLSKKAV EALEPRMKVHYVGVI----RKILQEKFHYKNEMQIPRVDKIVINMGIG-EATSDSKKPSIAAGDLSLITGQKAVVTYASS SIAGFKVREGMPLGAKVTLRKDRMFEFLDRLVTIALPRVRDFRGLNP-K------------------------------- ------------------------------------------------------MSRIG-K--KPIPVPSGVTAS-I--- -E-G--Q-LIKAKGPKGELSYIV--ND-E--VLVKLED-NI--VSV----T-P--RDQKDAR-SKWGMSHSMIRNIFCGV KDGFEKKLEISGVGY--RAALQG-KN--IQLS--LGFSHDVVYKV-P-S-DVSVAVP--K-PTEIVVSG-IDKQKVGQIA AEIRGYR------GPEPY---KGKGIKYVDESLVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSVKDVIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDRNAAVLVD-NKKE-PIGTRIF GPVPRELR-GKNHMKIVSLAPEVLMK-L--NELRDHEGA-TKNRKRIG-RGIGSGT-GKTGGCGVKGQKSRSGVS-L--- --NGF-E-GGQMPIYRRLPK-RG--FKNVSLGRIVDVAALKDA-GIIRVR---------LLS--DGE-L-K-S-K-IVF- NISGASKVARTKIEKVGGQI-K---QFK--GRI---HGAS-KGGTDLNFG----------AYGLKVV--EPERITARQIE AARRAITRYM------KRSGRVWIRVFPDLPVTSKPTEVRMGKGK---------GSVDYWAARVAP-GRIMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-ISKEIIQHRAKRVRRQI--KAAANGRPRLSVYRSNQNIYAQIIDD---V--RGCTL ASACTL-EEGM-KKSL----RSG-SDKKAAFAVGKLIAER--AKKSG-INEVVFDRGAYVYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVTRMIRVSPQK LNLVAAMIRGKKVDVALADLMFS---------------------------------RKRIAQTVKKTLESAIAN----A- ENNH-DLDIDSLIVSEAHVGKSIVMKRFHVRGRGRASRIERPFSHLTVIVREMKKIRKGDRVVILSGN------DK-GRS GEVIKVNPGES--KAL--VRGINMVKRHQR----QT--QK-Q-E-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRM---NA--------DGKVR---FAKRSG---ELI--MGQKINPIGLRLG--VN-QTWSSRWYA------DSG E--YGRLLHEDLKIRSYV--MEELK-----QAAISKVIIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRHQLSEMTS LNIVEIRK---PEIDATIIAQSVAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYSTAEARTAYGVCGVKVWVFMSMSDPLGDMLTRIRNAISRKKSKVVT-PASKLRARVLDVLKLEGYICGYN QID----S---GN---GKFEFEIELKYF---ENS-----------SVIRTISRISKPGRRVYVSTKSILQVANGLGISIL STPKGVMTDHEAREQNVGGELLCRVFMNGQNIRIRLEAFDHRILDVSTQEIVSTAKRTGANVRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEMRTHKRLLDIIDPTPQTVDALMKLDLSAGVNVEIKLKRILQGVVVSDKSDKTIIVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKIGDQVSIQESRPISKDKRWIVVK--DSV------------------------------- -MVRSV-WKGPFVDG-YLLGKAEKVRA---SGRNE----VIKIWSRRSTILPQFVGLTFGVHNGNKHIPVFVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Bartonella_bacilliformis_KC583_2 Concatenation of 2 sequences MALKHFNPTTSGQRQLVIVDRSG-LYKG------------KP-VKTLTEGLLSKGGRNNSGKITARF-QGGRHKRS---- YRFIDFK-R--LK-LDVSAKVERLEYDPNRTAFIALIRYE-DGQLSYILAPQRLDVGDTVVAGL-S-VD-VKPGNAMPLG NMPVGAIVHNVEMKPGKGGQIARSAGAYAQLVGR--DQGMAILRLNSGEQRLVSSNCFATVGAVSNPDHGNINDGKAGRS -RWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGKPTKGKRTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VITQKLGMTSIYN-DTGE---------RVPVTVLRLENCQ VIAQR----TVE----K--NGY--TAVQLGV-------GL--ATSK----------ALRGHFK----------------- ---AL-VEPKAKIVEFRV--------SSDNLL-----DV---GT-EITV--E-H-FVPGQRVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRA-HGSTGQC-QDPG-KVFKGKKMAGHMGQVRVTTQNVEVVSIDVDRG---------------- ----------LILVRGA-VSGSKGAWVLVR--MDLIIKT-LDGKKT-GELSVSEHVF----GL-VP-REDILQRVVRWQL ARRQKGTHKVQGRSD--------IS-RTGAKMY---------KQKGTGRAR--------HSS---AR-AP----QF---- RGGGKAHGPV-I-RSHAHGLPKKSRALGLRLALSAKFKAN----------------D-LIVIDEF----NLQ-D------ --PKTKLLI--GGKED--V---NFFRAASNIPNID-V---------------LPIQGINVYDILRRSK----LVLSKKAV EALEPRMKVHYVGVI----RKILQEKFHYKNEMQIPRVDKIVINMGIG-EATSDSKKPSIAAGDLSLITGQKAVVTYASS SIAGFKVREGMPLGAKVTLRKDRMFEFLDRLVTIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARELLRAFNFPF-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSVKDVIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDRNAAVLVD-NKKE-PIGTRIF GPVPRELR-GKNHMKIVSLAPEVL-------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------K---QFK--GRI---HGAS-KGGTDLNFG----------AYGLKVV--EPERITARQIE AARRAITRYM------KRSGRVWIRVFPDLPVTSKPTEVRMGKGK---------GSVDYWAARVAP-GRIMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-I------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------DNE-AKAVTRMIRVSPQK LNLVAAMIRGKKVDVALADLMFS---------------------------------RKRIAQTVKKTLESAIAN----A- ENNH-DLDIDSLIVSEAHVGKSIVMKRFHVRGRGRASRIERPFSHLTVIVREMKKIRKGDRVVILSGN------DK-GRS GEVIKVNPGES--KAL--VRGINMVKRHQR----QT--QK--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRM---NA--------DGKVR---FAKRSG---ELI--MGQKINPIGLRLG--VN-QTWSSRWYA------DSG E--YGRLLHEDLKIRSYV--MEELK-----QAAISKVIIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRHQLSEMTS LNIVEIRK---PEIDATIIAQSVAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYSTAEARTAYGVCGVKVWVF--------------------------------------------------- -------------------------------------------------------------------------------- --------------------------MNGQNIRIRLEAFDHRILDVSTQEIVSTAKRTGANVRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEMRTHKRLLDIIDPTPQTVDALMKLDLSAGVNVEIKLKRILQGVVVSDKSDKTIIVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKIGDQVSIQESRPISKDKRWIVVK--DSV------------------------------- -MVRSV-WKGPFVDG-YLLGKAEKVRA---SGRNE----VIKIWSRRSTILPQFVGLTFGVHNGNKHIPVFVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Bartonella_henselae_Houston-1 Concatenation of 2 sequences MALKQFNPTTPGQRQLVIVDRSC-LYKG------------KS-VKTLTEGLSSKGGRNNRGRVTARF-QGGGHKRS---- YRFVDFK-R--FK-RDVPAKVERLEYDPNRTAFIALIRYE-DGQLSYILAPQRLDVGDSVIAGS-N-VD-IKPGNAMPLG NMPVGTIIHNVEMKPGKGGQIARSAGAYAQLVGR--DQGMAILRLNSGEQRLVSSGCFATVGAVSNPDHANINDGKAGRS -RWR-----GRR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGKPTKGKRTR-SNKA-TD-K-FIMRTR --------------------------------MRS---G-VIAQKLGMTRIYN-DAGE---------HVPVTVLRLENCQ VVAQR----TVE----K--NGY--TAVQLGV-------GF--ATSQ----------ALRGHFK----------------- ---AS-VEPKAKIAEFRV--------SPDNLL-----DI---GT-EITA--E-H-FVPGQRVDVTGTTIGKGFAGVMKRH NFGG-HRASHGNSITHRA-HGSTGQC-QDPG-KVFKGKKMAGHMGQVRVTTQNIEVVSTDVERG---------------- ----------LILVRGA-VSGSKGAWILVR--MDLLIKT-LDGNEV-GKLKVSESVF----GL-VP-REDILQRVVRWQL ARRQQGTHQSQGRSD--------VS-RTGAKMF---------KQKGTGRAR--------HSS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHTLPKKIRALGLRFALSAKLKAD----------------D-LIVVDEF----NVK-D------ --AKTRLLI--GNEVD--L---NFSRATSNIPNID-I---------------LPIQGINVYDILRRSK----LVLSKAAV EVLEPRMKTHYFEVV----RKTLQEKFNYKNVMQIPRVDKIVINMGIG-EATADSKKPSIAAEDLGLITGQKAVVTRARN SIATFKVREGMPLGAKVTLRKDRMFEFLDRLVTIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARELLRAFNFPFMSRIG-K--KPISVPSGVTAT-V--- -E-G--Q-LVKAKGPKGELSYLV--ND-E--VLVKLEE-SF--ISV----S-P--RDQKDAR-SKWGMSRSMIENIFCGV KDGFEKRLEINGVGY--RAALQG-KD--IQLS--LGFSHDVIYKV-P-S-GVTVSIP--K-PTEIVVSG-IDKQQVGQVA AEIREYR------RPEPY---KGKGIKHADERIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSVKDAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDGNAAVLVD-NKKE-PIGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NELSDCKGA-IRNRKRVG-RGIGSGT-GKTGGRGVKGQRSRSGVS-L--- --NGF-E-GGQMPIYRRLPK-RG--FRNVSLGRIVDIIALKEA-GIIRVR---------LLS--DGE-L-K-V-K-ISF- NVSYASKAARLKIEKAGGQV-K---QFK--GRI---HGVS-KGGTDLNFG----------AYGLKAV--EPERITARQIE AARRAITRYM------KRSGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWAARVAP-GRIMFEL--DG-- IPEDVAREALRLGAAKLPIKTRF-ISKDIIQRRARRVRRRI--KMVSGNRLRLSIYRSNQNIYAQIIDD---L--RGCTL VSASTL-DGDL-KKSL----KSG-SDKEAAFAVGKLIAER--AKKAG-VNEVVFDRGAYVYH--GRVKALAEAAREGGLN F-------------------------------------------------------------DNE-AKAVARTIRVSPQK LNLVAAMIRGKKVGAALADLTFS---------------------------------RKRIAGTVKKTLESAVAN----A- ENNH-DLDIDSLVVAEAYVGKSIVMKRFHVRGRGRASRIERPFSHLTIIVREMQKIRKGDKVIVLSGK------DK-GCS GEVIKVNPKEN--RAF--VRGVNMIKRHQR----QT--QN--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV---NA--------DGKVR---FAKRSG---ELI--MGQKINPIGLRLG--VN-RTWDSRWYA------DSG E--YGRLLHEDLKIRLYV--LEELK-----QAAVSKIVIERPH-K-KCRVTIYSARPGLIIGKKGADIEKLRRKLSEMTS LNIVEIHK---PEIDATIIAQSIAQQLERRVAFRRAMKRAVQSALRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRSDVDYGTAEAKTAYGICGVKVWVFMSMSDPLGDMLTRIRNALARKKGKVVT-PASKLRARVLDVLQSEGYIRGYN QVD--LGD--------GKSEIEIELKYF----EG-------L---AAIREISRVSKPGRRVYVSAKSIPHVANGLGISIL STPKGVMADYEARKQNVGGELLCRVFMNSQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLK KTVRQSKKYKAHDES--NQFKIGDQIFIQESKPISKDKRWIVVK--DSV------------------------------- -MVRSV-WKGPFVDG-YLLGKAEKVRA---SGRNE----VIKIWSRRSTILPQFVGLTFGVHNGNKHIPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Bartonella_quintana_Toulouse Concatenation of 2 sequences MAFKHFNPTTPGQRQLVIVDRSC-LYKG------------KS-VKALTAGLSSKGGRNNHGRVTARF-QGGGHKRS---- YRFVDFK-R--LK-RGVFAKVERLEYDPNRTAFIALIRYE-DGQLSYILAPQRLDVGDSIIAGS-N-VD-VKPGNAMPLG NMPVGTIIHNVEMKPGKGGQIARSAGTYAQLVGR--GQGMVILRLNSGEQRLVSGSCFATVGAVSNPDHANINDGKAGRS -RWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGKSTKGKRTR-SNKA-TD-K-FIMHTR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRLENCQ VIAQR----TIE----K--NGY--TAVQLGV-------GF--ATSR----------ALRGHFK----------------- ---VS-VEPKAKIAEFRV--------SPDNLL-----DI---GT-EITA--Q-H-FVPGQRVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRA-HGSTGQC-QDPG-KVFKGKKMAGHMGQVRVTTQNIEVVSTDVERG---------------- ----------LILVRGA-VSGSKGAWILVR--MDLVIRT-LDGNEA-GRLKVSESIF----GL-VP-REDILQRVVRWQL ARHQQGTHHSQGRSD--------VS-RTGAKMF---------KQKGTGRAR--------HSS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHDLPKKIRVLGLRLALSAKLKAN----------------D-LIIVDEL----NVK-E------ --AKTKLLV--GGKED--I---NFSRAASNIPNID-I---------------LPIQGINVYDILRRSK----LVLSKAAV EALEPRMKTRYFEVI----RKTLQEKFNYKNAMQIPRVDKVVVNMGIG-EATIDSKRPSLAAEDLGLITGQKAVVTRARN SIATFKVREGMPLGAKVTLRKDRMFEFLDRLVTIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARELLRAFNFPFMSRIG-K--KPISVPSGVTAT-V--- -E-G--Q-LVKAKGPKGELSYIV--ND-E--VLVKFEG-NV--ISV----S-P--RDQKDAR-SKWGMSRSMIENIFCGV KNGFEKKLEINGVGY--RAALQG-KD--VQLS--LGFSHDVIYKV-P-P-GITVTVP--K-PTEIVISG-IDKQQVGQVA AEIREYR------RPEPY---KGKGVKHADECIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSVKDAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDSNAAVLVD-NKKE-PIGTRIF GPVPRELR-GRNHMKIISLAPEVLMK-L--NELGNCKGA-TRNRKRVG-RGIGSGT-GKTSGRGVKGQKSRSGVS-L--- --NGF-E-GGQMPIYRRLPK-RG--FRNVSLGRIVDIIVLKEA-GIIRVR---------LLS--DGE-L-K-A-K-ITF- NVSYTSKAARIKIEKAGGRV-K---QFK--GRI---HGVS-KGGTDLNFG----------AYGLKAV--EPERITARQIE AARRAITRYM------KRSGRVWIRIFPDLPVTSKPTEVRMGKGK---------GGVEYWAARVAP-GRIIFEI--DG-- VLEDVAREALRLGAAKLPIKTRF-ISKDIIQRRALRVRRRI--KMVSHDRPRLSVYRSNQNIYAQIIDD---S--RGCTL VSASTL-EGDL-KKSL----KSG-SDKQAAFAVGKLIAER--AKKAG-VNEVVFDRGAYVYH--GRVKALAEAAREGGLN F-------------------------------------------------------------DNE-AKAVARTIRVSPQK LNLVVAMIRGKRVGVALADLAFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDIDSLIVAEAYVGKSVVVKRFHVRGRGRASRIERPFSHLTIIVREMQKIRKGDKVVVLSGK------DK-GCS GEVIKVNPKEN--KAF--VRGVNMVKRHQR----QT--QK--QE-AGIVSKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRM---NV--------DGKVR---FAKRSG---ELI--MGQKINPIGLRLG--VN-RTWDSRWYA------DSG E--YGRLLHEDLSIRLYV--LEELK-----QAAISKVIIERPH-K-KCRVTIYSARPGLIIGKKGADIEKLRRKLSEMTS LNIVEIHK---PEIDATIIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRSDVDYGTAEAKTAYGICGVKVWVFMSMSDPLGDMLTRIRNALARKKGKLVT-PASKLRACVLDVLQSEGYIRGYN QVD----L-G-D----GKSEIEIELKYF----EG-------L---AAIRELSRVSKPGRRVYVSAKSLPQVANGLGVSIL STPKGIMADHEAREQNVGGELLCRVFMNSQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRILQGVVVSDKSDKTVVVKVERRYSHPLLK KTVRQSKKYKAHDEN--NQFKIGDQISIQESKPISKDKRWIVVK--DSV------------------------------- -MVRSV-WKGPFVDG-YLLGKAEKVRS---SGRNE----VIKIWSRRSTILPQFVGLTFGVHNGNKHIPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Bartonella_tribocorum_CIP_105476 Concatenation of 2 sequences MALKQFNPTTPGQRQLVIVERSG-LYKG------------KP-VKMLTEGLSSKGGRNNRGRVTARF-QGGGHKRS---- YRFVDFK-R--LK-RDVLAKVERLEYDPNRTAFIALIRYE-DGQLSYILAPQRLGVGDSVVAGS-N-VD-VKPGNAMPLG NMPVGTIIHNVEMKPGKGGQIARSAGAYAQLVGR--DHGMAILRLNSGEQRLVSSSCFATVGAVSNPDHGNINDGKAGRS -RWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGKPTKGKRTR-SNKA-TD-K-FIMRTR --------------------------------MRS---G-VIAQKLGMTRIYN-DAGE---------HVPVTVLRLENCQ VVAQR----TVE----K--NGY--TAVQLGV-------GF--ATSQ----------ALRGHFK----------------- ---AS-VEPKAKIAEFRV--------SPDNLL-----DI---GT-EITV--E-H-FVPGQRVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRA-HGSTGQC-QDPG-KVFKGKKMAGHMGQVRVTTQNIEVVSTDIERG---------------- ----------LILVRGA-VSGSKGSWILVR--MDLVIKT-LDGHEA-GKLKVSESIF----DL-VP-REDILQRVVRWQL ARRQQGTHQSQGRSD--------VS-RTGAKMF---------KQKGTGRAR--------HSS---AR-AP----QF---- RGGGKAHGPV-F-RSHAHDLPKKIRALGLRLALSAKLKAK----------------D-LIVVDEL----AVK-D------ --AKTKLLI--GGQED--I---NFFRAASNIPNID-V---------------LPIQGINVYDILRRSK----LVLSKAAV EALEPRMKTHYFEVI----RKALQEKFNYKNAMQIPRIDKIVINMGIG-EATADSKKPSLAAEDLGLITGQKAVVTRARN SIATFKVREGMPLGAKVTLRKDRMFEFLDRLVTIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARELLRAFNFPFMSRIG-K--RPISIPSGVTAT-V--- -E-G--Q-LVKAKGPKGELSYVV--ND-E--VLVKFEE-NV--ISV----M-P--RDQKDAR-SKWGMSRSMIENIFCGV KDGFEKRLEINGVGY--RAALQG-KD--IQLS--LGFSHDVVYKV-P-S-GVTVTVP--K-PTEIVISG-IDKQQVGQVA AEIREYR------RPEPY---KGKGVKHADERIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSVKDAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDSNAAVLVD-NKKE-PIGTRIF GPVPRELR-GRNHMKIISLAPEVLMK-L--NELRDCEGA-TKNRKRIG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -LNGF-E-GGQMPIYRRLPK-RG--FKNVSLGRIVDMIALKEA-GIIRVR---------LLS--DGD-L-K-A-K-ITF- HVSGASQAARVKVEKVGGQV-K---QFK--GRI---HGVA-KGGTDLNFG----------AYGLKAV--EPERVTARQIE AARRAITRYM------KRSGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWAARVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-ISKDIIQRRARRVRRRI--KMVSHDRPRLSVYRSNQNIYAQVIDD---L--RGCTL VSASTL-ESDL-KKSL----KSG-ADKEAAFAVGKLIAER--AKKAG-VNEVVFDRGAYVYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVTRTIRVSPQK LNLVAAMIRGKRVNVALADLTFS---------------------------------RKRIAATVKKTLESAIAN----A- ENNH-DLDIDSLIVAEAYVGKSIVMKRFHVRGRGRASRIERPFSHLTIIVREMQKIRKGDKVVVLSGK------DK-GCS GEVIKVSPKEN--KAF--VRGINMVKRHQR----QT--QK--QE-AGIISKEAPVHLSNLA-IADPKD-------GK--P --TRVGFRM---NA--------DGKVR---FAKRSG---ELI--MGQKINPIGLRLG--VN-RTWDSRWYA------DSG E--YGRLLHEDLRIRSYV--LEELR-----QAAISKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRRKLSEMTS LNIVEIRK---PEIDATIIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRSDVDYGTAEAKTAYGICGIKVWVFMSMSDPLGDMLTRIRNALGRKKDKVVT-PASKLRAHVLDVLQSEGYIRGYN QVD----L-G-D----GKAELEIELKYF----EG-------M---AAIRDISRVSKPGRRVYVSAKSLPQVANGLGISVL STPKGVMADHEAREQNVGGELLCRVFMNSQNIRIRLKAFDHRILDTSTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVISDKSDKTVVVKVERRYSHPLLK KTVRQSKNYKAHDEN--NQFKIGDQVSIQESRPISKDKCWIVVK--DNV------------------------------- -MVRSV-WKGPFVDG-YLLGKAEKVRA---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGNKHIPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Beijerinckia_indica_indica_ATCC_9039 Concatenation of 2 sequences MALKTFKPITPSLRQLVIVDRSN-LYKG------------KP-VKQLTEGKSSSGGRNNNGRVTVRF-RGGGHKQT---- YRIIDFK-RR--K-LDMPAKVERIEYDPNRTSFIALIRYA-DDELSYIIAPQKLAVGDEVISGQ-Q-VD-VKPGNAMALA NMPVGTIVHNIEMKIGKGAAMVRSAGTYAQVVGR--DQGYVIVRLNSGEQRLIHGQCFATVGAVSNPDHMNASIGKAGRS -RWL-----GRR-P-HNRGVTMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-T-NKSTD-K-FIVTSR --------------------------------MRS---G-VIAQKLGMTRVFT-DAGE---------HIPVTVLKLDGCQ VVGHR----TKE----Q--NGY--VAVQLGI-------GR--AVSK----------AERGRF------------------ ---VAKVEPKLKLAEFRV--------DDATLL-----PI---GA-EITA--D-H-FVVGQFVDVTGTSTGKGFAGAMKRW NFGG-LRATHGVSISHRS-HGSTGGR-QDPG-KTFKNKKMAGHLGTERVTTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGTAGGWIYVR--MKIDITS-VNGETA-GSIDLDDAIF----GL-EP-RVDLIARMIRYQL AKRRAGTHQSLGRAD--------IH-RTGKKMY---------KQKGTGSAR--------HGS---AR-AP----QF---- RGGGKAFGPV-A-RSHEHDLPKKIRALALKHALSAKAKDG----------------G-IIIWNDA----KIP-E------ --AKTKLII--DGAEE--T---NFSLAARNIPQID-V---------------LPVQGINVYDIVRRDK----LVLTTAAI NALEPRLKKFYEETV----KPKLIEEFGYKNPLEIPTIEKIVLNMGVG-DAVNDTKRVTLAAADLSLIAGQKPVITRARK AIATFKVRENMPIGAKVTLRKTRMYEFLDRLVTIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEID-----YDKA ESILGMDIIVCTS-----------------------AKTDDEARALLRAFNFPFMSRIG-K--KPVVIPAGVTAK-V--- -E-G--Q-AISVKGGKGELHFTA--PD-Y--VSVALEG-TQ--IAV----S-P-RSEDKKAR-AAWGMTRSIVNNLVIGV SQGFERKLEITGVGY--KAAVQG-KN--LQLS--LGYSHDISFPI-P-D-GIAIAAP--K-PTEVSITG-IDKQRVGQIA AEIRALR------PPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDIKRADGSVIRFDTNAAVLIN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDISDNPGS-SKSRMRVG-RGIGSGK-GKTCGRGVKGQKARTGVA----- -IKGF-E-GGQMPIHRRLPK-RG--FWNVNLGRIVTIEALVEA-GVCAVK---------ILG--NGE-L-K-A-K-LTF- EVASASKTAVAAIEQLGGSI-K---AFK--GRI---HGAA-KGGFELNFG----------EFGLKAM--EPERITARQIE AARRAMTRHM------KRAGRVWIRIFPDVPVSKKPTEVRMGKGK---------GAPEFWAARVAP-GRIMFEL--DG-- VPADLAREALRLAAAKLPIKTRF-IDIEATERRKARVRRSL--RARAYGKPRLSVFRSSKQIYCQIIDD---G--EGKTL VAASSL-EKAN-REGL----KTG-ATVEAAKIIGKLIAER--AVQAG-IKDVIFDRGAYMYH--GRVKALADGAREGGLN F-------------------------------------------------------------DNE-AKAVARMLRVSPQK LNLVAQLIRGKKVDKALADLEFS---------------------------------RKRIAYDVKKTLESAIAN----A- ENNH-SLDVDDLIVAEAFVGKAMVMKRFSPRARGRSGRIEKPFAHLTIVVREAAKIKKGDKVVVLAGR------DK-GRS GEVLQVLPKED--RAL--VRGINLVKRHQR--------QTAKQE-AGIYTKEATIHLSNLA-LADPKD-------GK--A --TRVGFKI---LE--------DGKVR---FAKHSG---DVI--MGQKVNPIGLRLG--IN-RTWDSRWFA------NKG E--YSKLLHEDMRIREVL--MKNLK-----QAAVSKIIIERPH-K-KCRVTIHSARPGVVIGKKGADIDKIRKLVSKLVV INIVEVRK---PEIDATLVADSIAQQLERRVAFRRAMKRAVQSAIRL-GAEGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADVDYGVATAHTAYGTCGIKVWIFMAVNDPLGDMLTRIRNAQMRRKGKVQT-PGSRLRAHVLDVLQEEGYIRGYS TTE----Y-GNG-----RSEFEIELKYF----DG-------L---PVIREIQRVSKPGRRVYTAVNAIPRVANGLGISII STPKGVMADHAAREANVGGEVLCKVFMNGQNIRIRLKAFDHRILDTSTKEIVSTAKRTGAQVRGPIPLPTKIEKFTVNRS PHVDKKSR-EQFEIRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVSDKQEKTIVVKVERRFTHPLLK KTVRRSKNYHAHDEA--GTYKIGDTVSIEETKPISRLKRWIVLETAAKA------------------------------- -MARSI-WKGPFVDG-YLLKKAEAARA---STRSE----VIKIWSRRSTILPQFVGLTFGVYNGHKHVPVSVTE-DMIGH KFGEFSPTRTFHGHA------A---DK----KAR------RG >ALPHA_Bradyrhizobium_japonicum_USDA_110 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-VKALTEGKHSSGGRNNTGRITVRF-RGGGHKQT---- LRIVDFK-RD--K-VDAPATVERLEYDPNRTAFIALVKYE-DGTQAYILAPQRLAVGDSVVAGN-Y-VD-VKPGNVMPLG NMPVGTIIHNIEVKIGKGGQLARSAGTYAQLVGR--DQDYVIIRLNSGEQRLVHGRCRGTIGAVSNPDHMNTSIGKAGRN -RWL-----GRK-P-HNRGVSMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-S-NKSTN-K-FILLSR --------------------------------MRS---G-VIAQKVGMTRVFT-EAGE---------HIPVTVLKLGNCQ VVGHR----TEE----K--NGY--VALQLGS-------GS--RMPK----------AERGQF------------------ ---VAKVEPKRRVEEFRV--------TADAMI-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSVGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTWKNKKMPGHMGVDRITTLNLRVVQLDVERG---------------- ----------LILVEGA-VPGSKGGWIRVRREMELKVTT-LEGKEA-GSVQLSDAIF----GL-EP-RQDIIARCVQWQL NKRQAGTHKAKGRAE--------IW-RTGKKMY---------KQKGTGGAR--------HGS---AR-VP----QF---- RGGGRAFGPV-V-RSHATDLPKKVRALALKHALSAKAKDG----------------D-LLVIDKA----ALE-A------ --AKTKLII--DGAEN--N---GFAAAARNIPNMD-V---------------LPIQGINVYDILRRQK----LVLTKAAI DALEPRLRAEYDAKI----RTAMTEKFGYENVMQVPRLDKVVLNMGVG-DSVNDRKKAETAAAELTQIAGQKAIVTYSRI AIATFKLRENQPIGCKVTLRKARMYEFIDRLVTVALPRVRDFRGLNP-KSFDGRGNYSLGIKEHIIFPEID-----FDKV TEARGMDITVCTT-----------------------AKTDEEARALLTAFNFPFMSRVG-K--RPVAVPSGVTAT-V--- -D-G--Q-TVKMKGPKGQLQFVV--HD-D--VEVKLES-GQ--IKV----K-P-RLETNRAR-ALYGTARAQVANLVEGV TKGFEKKLEITGVGY--RAAMQG-KN--LQLA--LGYSHDVIYTI-P-E-GITITVP--K-PTEITVTG-SDIQRVGQVA AEIRSYR------PPEPY---KGKGVKYVGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ATIGDIIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLIN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SDIADNAGS-RKKRMRVG-RGIGSGK-GKQSGRGGKGQTARSGVR----- -IKGF-E-GGQMPMHRRLPK-RG--FNNINLDRLVNVEALVKG-GVLRLR---------LLG--RGE-L-K-S-K-LNI- EVHGATKTAIAAVEKAGGSV-K---AHK--GRI---HGVA-SSGATLAFG----------QYGLKAT--EPERVTARQIE AARRALTRHM------KRAGRVWIRVFPDLPVSKKPAEVRMGSGK---------GSPELWVARVKP-GRVLFEI--DG-- VNTQTAREALTLAAAKLPIKTRF-VVTNARRKRSVRLKLRR----SGGGRPRLSVFRSSKHIYAQVIDD---L--KGETL ASASSL-EKSM-RDGG----KTG-ADIDAAKAVGKLLAER--AAEKG-VKEVVFDRGSYLYH--GRVKALADAARESGLS F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAQLIRGRKAAAALADLQFS---------------------------------RKRIAVDVKKCLESAIAN----A- ENNH-DLDVDDLVVAQAFVGNGLVMKRFAARGRGRSGRVYKPFSQLTIIVRQAAKIRKGDKVVVLTGR------DK-GRT GEVFEVRPDAG--TAL--VRGINMVKRHQK----QT--QA-Q-E-GGIISKEAPIQLSNIA-YVG-KD-------GK--P --TRVGFKI---LA--------DGKVR---IAKSSG---AEI--MGQKINPIGLRLG--IN-RTWDSRWFA------GKQ E--YGKLLHEDVKIREIL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKRVADIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRSKTKVST-PGSRMRENVLEVLKSEGYIRGYA TVE--HSS--------GRSEIEIELKYF----DG-------E---PVIREIERVSKPGRRVYASVKNLPRVNNGLGISVL STPKGIMADHSARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKTAKTVVVRVDRRFTHPIYK KTIRRSKNYHAHDEN--NEFKPGDMVWIEESKPISKLKRWVVIR--KKS------------------------------- -MVRSV-WKGPFVEG-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLTFGVYNGQKHVPVAVNE-EMVGH KFGEFSPTRTFHGHS------G---DK----KAK------KA >ALPHA_Bradyrhizobium_sp_BTAi1 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-VKALTEGKLSSGGRNNTGRITVRF-LGGGHKQS---- YRMVDFK-R--DK-VDVPATVERLEYDPNRTAFIALVKYQ-DGELAYILAPQRLAVGDTIVAGN-Y-VD-VKPGNVMPLG NMPVGTIVHNIEVKIGKGGQLARSAGTYAQIVGR--DQDYVIVRLNSGEQRLVHGRCRGTIGAVSNPDHMNTSIGKAGRK -RWM-----GRR-P-HNRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-TNKS-TD-K-FILLSR --------------------------------MRS---G-VIAQKVGMTRVFT-ETGE---------HIPVTVLKLGNCQ VVGHR----TTE----K--NGY--VALQLGS-------GS--RMPK----------AERGQF------------------ ---VAKVEPKRKVAEFRV--------SEDSLI-----PV---GA-EILA--D-H-FVVGQFVDVTGTTVGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTWKNKKMPGHMGVDRVTTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGSKGGWISVR--MELKVTT-LEGKDA-GSVQLSDAIF----GL-EP-RVDIIQRCVQWQL NKRQAGTHKAKGRAE--------IW-RTGKKMY---------KQKGTGGAR--------HGS---AR-VP----QF---- RGGGRAFGPV-V-RSHATDLPKKVRALALKHALSAKAKDG----------------D-LVVLENA----TLE-A------ --AKTKLII--DGAEH--N---GFAAAARNIPNLD-V---------------LPIQGINVYDILRRQK----LVLTKAAI DALEPRLRTEYDRKI----KSALTEKFGYANVMQVPRLDKVVLNMGIG-EAVNDRKKAETAAADLSLIAGQKAVVTYSRV AIATFKLRENQPIGCKVTLRKAKMYEFIDRLINVALPRVRDFRGLNP-KSFDGRGNYSLGIKEHIIFPEID-----FDKA GESWGMDITVCTT-----------------------AATDDEARALLTAFNFPFMSRIG-K--KPVTVPSGVTAT-V--- -D-G--Q-TVKMKGPKGQLQFIV--HD-D--VDVKFEN-GQ--VRV----A-P-RSETKRAR-SLYGTARAQIANLVEGV TKGFEKKLEITGVGY--RAAMQG-KN--LQLA--LGYSHDVVYQI-P-E-GITIAVP--K-PTEITVTG-IDPQRVGQVA AEIRAYR------PPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ATVGDIIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLIN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SDIADNAGA-RKKRMRVG-RGIGSGK-GKTSGRGGKGQTARSGVR----- -IKGF-E-GGQMPMHRRLPK-RG--FNNINLDRIINAEALVKS-GALRVR---------LLG--RGE-I-T-A-K-VNI- EVHGASKSAIAAVEKAGGTV-K---AHK--GRI---HGVA-SSGATLAFG----------QFGLKAM--EPDRVTARQIE AARRALTRHM------KRAGRVWIRVFPDLPVSKKPAEVRMGSGK---------GSPELWVARVKP-GRVMFEI--DG-- VSNQIAREALLLAAAKLPIKTRF-VAKVTNARRKQRVRLSL--RRSAGGRPRLSVFRSSKHIYAQVIDD---Q--KGETL ASASSM-EKEM-RSSG----NTG-ADIDAAKAVGKLLAER--AVKAG-IKEVVFDRGGYLYH--GRVKALADAARESGLS F-------------------------------------------------------------DNE-AKAVARMLRVSPQK LNLVAQMIRGRKASAALADLQFS---------------------------------RKRIAVDVKKCLESAIAN----A- ENNH-ELEVDDLVVSQAFVGKGIVMKRFSPRGRGRSGRVFKPFSQLTIIVRQAAKIRKGDKVIVLTGR------DK-GRT GEVFEVRPDAG--TAL--VRGINLVKRHQK----QT--QN-Q-E-GGIITKEAPIHLSNVA-YVG-KD-------GK--P --TRIGFKV---QA--------DGKVR---VAKSSG---VEI--MGQKINPIGLRLG--IN-RTWDSRWFA------GKA E--YGKLLHEDVKIREIL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKRVADIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRSKSKVTT-PGSKMRASVLEVLKSEGYIRGYA TLE----H-P-S----GRSEIEIELKYF----DG-------E---PVIREIERVSKPGRRVYTSVKNLPRVNNGLGISVL STPKGIMADHSARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYK KTIRRSKNYHAHDES--NEFKPGDMVWIEESKPISKLKRWTVVR--KKT------------------------------- -MVRSV-WKGPFVEA-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLTFGVYNGQKHVPVAVNE-EMVGH KFGEFSPTRTFHGHS------G---DK----KAK------KA >ALPHA_Bradyrhizobium_sp_ORS278 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-VKALTEGKQSSGGRNNTGRITVRF-LGGGHKQS---- YRTVDFK-R--DK-VDVPATVERLEYDPNRTAFIALVKYQ-DGELAYILAPQRLAVGDTIVAGN-Y-VD-VKPGNVMPLG NMPVGTIVHNIEVKIGKGGQLARSAGTYAQLVGR--DHDYVIVRLNSGEQRLVHGRCRGTIGAVSNPDHMNTSIGKAGRK -RWM-----GRR-P-HNRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-TNKS-TD-K-FILLSR --------------------------------MRS---G-VIAQKVGMTRVFT-ETGE---------HIPVTVLKLGNCQ VVGHR----TTE----K--NGY--VALQLGS-------GS--RMPK----------AERGQFV----------------- ---AK-VEPKRKLAEFRV--------SEDSLI-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSVGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTWKNKKMPGHMGVDRITTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGSKGGWISVR--MELKVTT-LEGKEA-GSVQLSDAIF----GL-EP-RADIIQRCVQWQL NKRQAGTHKAKGRAE--------IW-RTGKKMY---------KQKGTGGAR--------HGS---AR-VP----QF---- RGGGRAFGPV-V-RSHATDLPKKVRALALKHALSAKAKDG----------------D-LVVLENA----TLE-A------ --AKTKLII--DGAEH--N---GFAAAARNIPNLD-V---------------LPIQGINVYDILRRQK----LVLTKAAI DALEPRLRTEYDRKI----KSALTEKFGYANVMQVPRLDKVVLNMGIG-EAVNDRKKAETAAADLSLIAGQKAVVTYSRV AIATFKLRENQPIGCKVTLRKAKMYEFIDRLINVALPRVRDFRGLNP-KSFDGRGNYSLGIKEHIIFPEID-----FDKA GESWGMDITVCTT-----------------------ATTDDEARALLTAFNFPFMSRIG-K--KPVTVPSGVTAT-V--- -D-G--Q-TVKMKGPKGQLQFLV--HD-D--VEVKFEN-GQ--VKV----A-P-RAETKRAR-SLYGTARAQIANLVEGV TKGFEKKLEITGVGY--RAAMQG-KN--LQLA--LGYSHDVVYQI-P-E-GITIAVP--K-PTEITITG-IDPQRVGQVA AEIRAYR------PPEPY---KGKGVKYAGEFIFRKEGK-------------------MADNSGARRVMCIKVLG-SKRR Y--ATVGDIIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLIN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SDIADNAGA-RKKRMRVG-RGIGSGK-GKTSGRGGKGQTARSGVR----- -IKGF-E-GGQMPMHRRLPK-RG--FNNINLDRIINAESLVKS-GALRVR---------LLG--RGE-L-K-A-K-INI- EVYGASKSAIAAVEKAGGTV-K---AHK--GRI---HGVA-SSGATLAFG----------QFGLKAM--EPDRVTARQIE AARRALTRHM------KRAGRVWIRVFPDLPVSKKPAEVRMGSGK---------GSPELWVARVKP-GRVMFEI--DG-- VSNQIAREALTLAAAKLPIKTRF-VAKVTNARRKQRVRLSL--RRSAGGRPRLSVFRSSKHIYAQVIDD---Q--KGETI ASASSM-EKEM-RSAG----NTG-ADIDAAKAVGKLLAER--AVKAG-IKEVVFDRGGYLYH--GRVKALADAARESGLS F--------------------------------------------------------------------MARMLRVSPQK LNLVAQMIRGRKASAALADLQFS---------------------------------RKRIAVDVKKCLESAIAN----A- ENNH-ELEVDDLVVSQAFVGKGIVMKRFSPRGRGRSGRVFKPFSQLTIIVRQAAKIRKGDKVIVLTGR------DK-GRT GEVFEVRPDAG--TAL--VRGINLVKRHQK----QT--QN-Q-E-GGIITKEAPINLSNVA-YVG-KD-------GK--P --TRIGFKI---QA--------DGKVR---VAKSSG---VEI--MGQKINPIGLRLG--IN-RTWDSRWFA------GKA E--YGKLLHEDVKIREIL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKRVADIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRSKSKVTT-PGSKMRASVLEVLKSEGYIRGYA TME----H-PSG-----RSEIEIELKYF----DG-------E---PVIREIERVSKPGRRVYTSVKNLPRVNNGLGISVL STPKGIMADHSARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYK KTIRRSKNYHAHDES--NEFKPGDMVWIEESKPISKLKRWTVVR--KKT------------------------------- -MVRSV-WKGPFVEA-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLTFGVYNGQKHVPVAVNE-EMVGH KFGEFSPTRTFHGHS------G---DK----KAK------KA >ALPHA_Brucella_abortus_bv_1_9-941 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTGS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGEVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRDRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRAYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_abortus_S19 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL----ASA-D------ --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTGS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGEVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRDRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR--------QTQTQE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRAYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT--EAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_canis_ATCC_23365 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKPLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTAS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRGRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQLIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRGYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_melitensis_ATCC_23457 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTAS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRDRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--VN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRGYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_melitensis_bv_Abortus_2308 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSFLRAFNFPFMSRIG-K--KPVPVPAGVTGS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGEVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRDRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRAYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_ovis_ATCC_25840 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-F-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTAS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRVRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRIGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRGYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGSKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_suis_1330 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GV--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTAS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRSAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFHVRGRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRGYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Brucella_suis_ATCC_23445 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSE-LYKG------------KP-VKPLTEGLSKKGGRNNTGRITVRF-QGGGHKRS---- YRFIDFK-R--RK-LDVVGTVERLEYDPNRTAFIALIRYT-DGELAYILAPQRLAVGDQVVAGN-S-VD-VKPGNAMPLS SMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-SNKA-TD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GM--ATSK----------AMRGHFK----------------- ---AE-VEPKAKLAEFRV--------SPDNLL-----EV---GV-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFGG-HRASHGNSITHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWILVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGSKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RNHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL---ASAD-------- --AKTKLLI--GGAED--A---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYQDNI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLAMIAGQKAVVTRARN SIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARSLLRAFNFPFMSRIG-K--KPVPVPAGVTAS-V--- -E-G--Q-TVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VRV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRIVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYAQIIDD---V--RGVTL AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AKAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDALIVAEAYVGKSIVMKRFH--VRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VSGINIVKRHQR----QT--QT--QE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEVDATLIAQTIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPLGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQAEGYIRGYT QSE---FE---N----GKAEIEIELKYY----EG-------V---PVIREITRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVLKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDFVSIQESAPISKDKRWVVLT-SEAA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Candidatus_Pelagibacter_ubique_HTCC1062 Concatenation of 2 sequences MALKTFKPYTKSTRGTILVDRAG-LWKG------------KP-FKALVEPKNSMRGRNNNGHITSRNMSGGGHKKM---- YRLVDFY-R--KK-IDMPGTVERIEYDPNRSCYIMLVKFD-DGQHFYYLAPQKIKVGDKVENGS-E-KE-IKVGNCMPLR DIPVGINIHNVELKPGAGGKIARSAGTSVTISGL--DGNYSLIKMTSGEVRKIDSRCMATIGVLSNPDQKNIKIGKAGRS -RWL-----GRR-P-HTRGVVMNPVDHPHGGGEGKT-A--GGRH-PVSP---TGQSAKGLKTR-D-NKSTD-K-FIVRRR --------------------------------SEI---A-LIGKKIGMTREFY-KTGR---------LVPVTVIKMEKAR VIQVI----EEE----K--RGY--KAVQLGF-------GK--ILTK----------AMKGLYK----------------- ---KN-TEAKKKLKEFRV--------KDTELY-----KE---GN-EFGL--E-I-FNEVKFVDTTSKTIGKGFAGAMKRH NFGG-LRATHGVSVSHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGDRVRTMQNLEIIKTDIENE---------------- ----------LLYLKGS-IPGSKNTEILVK--MKIDKLN-LDGKK--DSIEVLDKIF----SA-KI-NKRLVDNVLYKTN ANYKGRHAKTKQQNE--------IT-GSTSKIY---------AQKGTGGAR--------HAS---RK-AP----IF---- VGGGVAHGPKGELAYKKRKLNKSEKKLSIASLITEKNKLN----------------N-LIIFSDF----GNE-I------ --KKTKLII--LDKSS-KE---KIEKSVRNIPNVK-V---------------TDINHFSAFDIIKFKK----VVFTESSI KELEPRLKELYYKEI----QPQLKETLGYKNTYMGPKVEKVVINMGLG-LDGADAKIMKSTEEDLGKITGQKPTVTKFKK SVANFKTRKGTNAGLKVTLRGNKMYEFLDRLVNIALPRIKDFRGLSP-KGFDKFGNYTFGIKEHIIFPEVN-----FDRI DKIRGLDIVVVIS-----------------------ALNKDHSFALLEKLNFPFMSKIG-K--ISISIPEKVKAV-L--- -S-G--S-VLNIEGPLGKKSLNI-DLE-M--FNLDVTE-GKE-ISI----S-P-KVKDQNSK-RLWGMNRSLINNAVIGS STGYEKILELVGVGY--RAALKD-KQ--LNLQ--LGYSHDINFDI-P-E-GIKIVVE--K-QTVVKVSG-SDKQQVGMVV SKIKAFR------KPEPY---KGKGIREQGQYILRKEGK----------MIQVQTELLVADNTGAKRIECIKVLG-SKRR Y--ASIGDTIVIAVKEALPK-G-------KVKKGSVHKAVVVRVKKGIHREDGSKVRFDNNAAVLVD-DKGE-PVGTRIF GPVTRELR-SRGQMKIISLAPEVL---M--TTLNTTGKVLYKKKMRVG-RGIGSGK-GKTSGRGVKGQKSRSGVA-I--- --KAF-E-GGQMPLYRRLPK-RG--FNAMNLEKIINMALLKKL-KLINLK---------ILG--TGE-I-K-D-K-VNI- EADLISKSAVEKLEKAGGTI-K---AHK--GRI---HGTA-TRASKINYG----------SFALKAM--APERIIGKQIE AARVALTRHM------KRQGRVWTRIFPNIPVSKKPVEVRMGKGK---------GAPEYWACRVKP-GRILFEI--DG-- VSETIAKEALYKASAKLPIKTKF-IKLNTIQRKKFRVTGKL-KKVASSDRLRLSISRSAKNISAQIIDD---V--KNITL VSCSSV-EKDI-RSM-----DKV-NKTEISKIVAEKLAKK--AQEKK-ISKIFFDRGIYKYH--GRVKVFAETLRKNGME F-------------------------------------------------------------VDT-VRSVNNNIRSSVRK LNPILKAIVGKKVDVAIRELQFS---------------------------------AKRITREIRKTVSSAVAN----A- ENNN-QYDIDKLIVKEAYCGKKVVMKRFRPRAKGRAAPILKPYSTITIILSE--MIKKGLKVRVLTGR------DK-KKE GEVIEIDRPNN--RAK--VQGINIVKKHVK----TT--KE--KK-GGIVSKESFIHISNLK-LIDEKA------------ ------------------------KTK---KTEAKK--------MGQKVNPVGFRLG--VN-RGWDSVWYA------KKK D--FGNYLIEDFKIRAYI--KKNVV-----NSGVSKVMIERTS-N-KCFVTIYTSRPGFVIGKKGSDIDKIKNNLSKFVT LNIKEVKK---PETNAYLVAENIAQQLVKRISYRRAMKRAMQSCLRL-GAKGIKVSISGRLGGNEIARTEWLREGSIPS- -HTLRADIDYAEAEALTTFGIIGIKIWIYMSLSDPIGDMIARIKNAQVRNHKKVAL-PSSNFKVKIADILKSEGFIKDYK IET----E---N----NKPTLSVDLKYY----SG-------N---PVISTFERVSKPGRRIFSSADSLPKINGGLGIAIV STPKGVMTDIEARKQKVGGEIICKVFMEKQNIRIKLRAYDNKILDASTEEIVNTVKRTGATIKGPIPLPTRIERYTVLKG PHIDKKSR-EQFETRTHKRLIDIIEPTPQTVEALMKLDLASGVDVEIKIKKILTGVVTSDKPNKTITVSVERKYSHPVLK KVVKVRKKYNAHDEN--NKFKTGDTVSIIECKPFSKNKKFQVMD---ES------------------------------- -MARSV-WKGPFVEE-SLIKKVEKQKL---DPKKM----PIKTWSRKSTIIPEFIGVSFLIYNGKKFIPVTISE-DMVGH KLGEFSPTRTFFGHT------P--AEK----KGK--PAEKKK >ALPHA_Caulobacter_crescentus_NA1000 Concatenation of 2 sequences MALKQFNPTSPGQRGLVLIDRSE-LHKG------------RP-EKKLVEGLTKSGGRGGNGRIAVRF-RGGGAKRL---- YRLVDFK-RR--K-QGV-ATVVRLEYDPNRTAFIALIKYQADGELAYILAPQRLKAGDEVVTAE-K-VD-VKPGNASPLR TLPIGTIIHNIELKPAKGGQIARSAGAYAQLVGR--DAGYAQIRLNSGELRMVLDTCMATVGAVSNPDHMNQNLGKAGRS -RHM-----GRR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---AGKPTKGAKTR-V-NKATD-K-FIIRSR --------------------------------QRT---G-VIAKKLGMTRFFD-EAGQ---------HVPVTVLSLDGCQ VTGVR----TVE----K--DGY--TALQLGA-------GA--KTSN----------AMRGHFK----------------- ---AA-VEPKRVVAEFRV--------EENALI-----EV---GA-ELTA--D-H-FVAGQKVDIQGVTVGKGFAGAMKRW NFGG-LRATHGVSVSHRS-HGSTGNR-QDPG-RTFPGKKMAGHLGQETVTTLNVTVWKVDVERG---------------- ----------LILVKGA-VPGHEGSYVKVR--MKLDVIK-LDGGKA-GSVDLDDAIF----GIDEI-RGDILQRVVTWQL AKRRSGNHKIQVRNE--------VS-RTSKKMY---------KQKGTGGAR--------HGS---RR-AA----QF---- VGGAKAHGPV-V-RSHAFDLPKKIRALALRHALSSKAKAG----------------S-LVVVDSV----ALT-E------ --AKTALVI--AGPED--A---NFKLAARNIPNVD-V---------------LPNAGLNVYDVLRRQT----LVLTKDAV EAISPRLKTVYRERI----RAAMKEQFGYTNEMQIPKLDKIVLNMGIG-EAVADSKKAQTALKDLQAIAGQKPVATKARK SIAGFKLREGMVVGAKVTLRKDRMYEFLDRLVTIALPRVKDFRGLNG-KSFDGRGNYAMGLKEHLVFPEIN-----YDQI EQIWGMDIIVCTT-----------------------AKSDQEAKALLKEFQFPFMSRIG-K--KAVAIPSGVQVT-L--- -A-G--Q-TVTVKGPKGQLSWTI--AD-E--VEVKQEG-AE--LLL----A-P-RVDTKRAK-GMWGLSRTLVANMVHGV TVGFEESLELVGVGY--RAAMKG-TA--LSLQ--LGFSHDVDVAA-P-A-GVTFAVP--K-QTEIKIAG-IDKQAVGEIA AKIRRIR------PPEPY---KGKGVRYAGEKVRRKEGK----------MIQMQTNLEVADNSGARRVMCIKVLG-AGRR Y--ASVGDVIVVSVKEAIPR-G-------RVKKGDVLRAVVVRVNQNLKRKDGSVIRFDKNAAVIVN-KQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLTK-L--NELAPREGS-TKGRMRVG-RGPGSGK-GKTAGRGVKGQKARSGVA----- -INGF-E-GGQMPLHMRMPK-RG--FNNVNLWRLLDAAALIAA-GVIRVK---------LLA--KGE-I-K-T-A-LKL- TVYSATEAAIKAVEAAGGSV-K---QFK--GRI---HGTS-KGGTLLNFG----------SYGLKAV--EPERITARQIE AARRAITRQM------KRQGRVWIRIFPDVPVTGKPAEVRMGKGK---------GAVDYWAARVAP-GRIMFEI--DG-- VPDDIAREALRLGAAKLPIRTRV-VPRESAAKRAQRVRTRL--KSLANGRPRLSVFRSSKNIYAQVIDD---E--RGVTL ASASTL-EAE----------GKG-ADKDAAAAVGKLVAER--AIEKG-VKDVVFDRGSYIFH--GRVKALADAAREAGLN F-------------------------------------------------------------AAE-AMCKVRTLRTSPRK LNLVAQSIRGLNVQRALNELEFS---------------------------------HKRIAQDVRKALYSAISN----A- ENNH-NLDIDSLVVAEAYVGKNLIMKRFSPRARGRATRVEKPFSEITIVVREAAKIKKGDRVVVLAGK------DK-GKQ GSVLQVLPKDN--RVV--VEGVNMVSRHTK----PT--QA-DPQ-GGIKNKEAALHVSNVA-VVD-SN-------GK--P --TRVGFKI----E--------GDKVR---VAKTTG---EVI--MGQKVNPVGLRLG--IN-RTWDSRWFA------DGN Q--YGKLLHQDLAVRAAL--KKRLY-----QAGVSRIIIERPH-K-KCRVTIYAARPGVIIGKKGADIDKLRKDLSIMVH LNIVEIRK---PETDAQLVAESIAQQLERRIAFRRAMKRSIQSAVRL-GAKGIRINVSGRLGGAEIARMEWYREGRVPL- -HTLRADIDFGFAEAKTTYGIIGVKTWIFMSMNDPLSDMIARIKNAAQRKRSKVST-PASKLRARVLDVLADEGYIRGYS LVE----K--PG----AFPEFEIELKYF----DG-------E---PVIAEISRVSKPGRRVYSSIKDLKPIKNGLGISIL STPKGVMSDTAARDANVGGEVLCRVYMDRQNIRIRLKAFDHRVLDHSTREIVNTAKRTGATVRGPIPLPTLIEKFTVNRS PHVDKKSR-EQFEIRTHKRVLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRILEGVVVSDKGDKTVVVKVERTIVHPVLK KIVRQSKKYHAHDEA--NAYKAGEAIRIIECAPKSKLKTWEVLP--KAS------------------------------- -MTRSV-WKGPFVDG-YLLKKADAALS---SGRKD----VIKTWSRRSTIMPQFVGLTFGVHNGHKHVPVLVSE-DMVGM KFGEFAPTRNFPGHA------A---DK----KAK------RK >ALPHA_Caulobacter_sp_K31 Concatenation of 2 sequences MALKHFNPTSPGQRGLVLIDRSE-LHKG------------RP-EKKLVEGLTKSGGRGGNGRIAVRF-RGGGAKRL---- YRLVDFK-R--RK-QGV-ATVVRLEYDPNRTAFIALIKYQADGELAYILAPQRLKAGDEVVTAD-K-VD-VKPGNTSPLR TMPIGTIIHNVELKPAKGGQIARSAGAYAQLVGR--DAGYAQIRLNSGELRMVLDTCLATVGAVSNPDHSNQNLGKAGRV -RHM-----GRR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRNPVTP---AGKPTKGAKTR-VNKA-TD-K-FIIRSR --------------------------------NRT---G-VIAKKLGMTRFFD-ETGQ---------HVPVTVLSLDGCQ VTAQR----TVE----K--DGY--TALQLGA-------GA--KTPN----------AMRGHFK----------------- ---NS-VEPKRIVAEFRV--------DEAALI-----EV---GA-EFTA--D-H-YVAGQKVDIQGITVGKGFAGAMKRW NFSG-LRATHGVSVSHRS-HGSTGQR-QDPG-RTFKGKKMAGHLGQETVTTLNVTVWKVDVERG---------------- ----------LILVKGA-VPGSEGSYVKVR--MKLDVIN-LDGGKA-GSVDLDDAIF----GIADI-RGDILQRVVTWQL AKRRSGNHKIQVRNE--------VS-RTGKKMY---------KQKGTGSAR--------HGS---RR-AA----QF---- VGGAKAHGPV-V-RSHAFDLPKKIRAMALRHALSSKAKSG----------------S-IIVLDTA----VLT-D------ --PKTALVI--APEVD--G---NFKLAARNIPNID-V---------------LPNAGLNVYDVLRRHT----LVLTKDAV EAISPRLKSEYRARI----RAAMKEQFAYTNEMQIPKLDKIVLNMGIG-EAVADSKKAQTALKDLMAIAGQKPVATKARK SIAGFKLREGMVVGAKVTLRKDKMYEFLDRLVTIALPRVKDFRGLNG-KSFDGRGNYAMGLKEHLVFPEIN-----YDQI EQIWGMDIIVCTT-----------------------AKTDQEAKALLKEFQFPFMSRIG-K--KAVAIPSGVNIT-L--- -D-G--Q-TVTVKGPKGQLSWTI--AE-E--ITISQEG-SD--LLL----V-A--RDDKRAK-SMWGLSRTLVANMVQGV TTGFEETLELVGVGY--RAAMKG-DA--LSIQ--LGFSHDVNVEA-P-A-GVTFAVP--K-QTEIKIAG-ADKQAVGEIA AKIRRIR------PPEPY---KGKGVRYAGEKVRRKEGK----------MIQMQTNLEVADNSGARRVMCIKVLG-AGRR Y--ASVGDVIVVSVKEAIPR-G-------RVKKGDVLRAVVVRVNQGMKRKDGSLIRFDKNAAVIVN-KQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLTK-L--NELAPAPGS-TKGRMRVG-RGPGSGK-GKTAGRGVKGQKARSGVA-I--- --AGF-E-GGQMPLHMRMPK-RG--FNNVNLWRLVSVADLVAA-GVIRVK---------LLG--KGE-I-K-S-A-LKL- TVYSATEAAIKAVEAAGGSV-K---QFK--GRI---HGTS-KGGTLLNFG----------SYGLKAV--EPERITARQIE AARRAITRQM------KRQGRVWIRIFPDVPVTGKPAEVRMGKGK---------GAVDHWAARVAP-GRIMFEI--DG-- VPDDIAREALRLGAAKLPIRTRV-VPRESAVRRAQRTRTRL--KALSNGRPRLSVFRSSKNIYAQVIDD---E--RGVTL ASASTL-EGEA--------ATKG-ADKDAAALVGKLVAER--AIEKG-VKDVVFDRGGYIFH--GRVKALADAAREAGLN F-------------------------------------------------------------ANE-AMCKVRTLRTSARK LNLVAQSIRGLNVQRALNELEFS---------------------------------HKRIAQDVRKALYSAISN----A- ENNH-NLDIDSLVVAEAYVGKNLVMKRFSPRARGRATRVEKPFSEITIVVREAAKIKKGDRVVVLAGK------DK-GKQ GAVTQVLVKAN--RVL--VQGVNLVQRHTK----AT--QA-DPQ-GGIKSKEAALHVSNVA-IVDSK--------GK--P --TRVGFKI---EG--------DKKVR---FAKTTG---EVI--MGQKVNPVGLRLG--IN-RTWDSRWFA------DGE Q--YGKLLHQDLAVRAML--KKRLY-----QAGVSRIIIERPH-K-KCRVTIYAARPGVIIGKKGADIDKLRKDLSVMVH LNIVEIRK---PETDAQLVAESIAQQLERRIAFRRAMKRSIQSAVRL-GAKGIRINVSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKTWIFMSMNDPLSDMIARIKNAATRKRAKVAT-PASKLRARVLDVLADEGYIRGYS LVE----K-P-G----AFPEFEIELKYF----DG-------E---PVIAEIARVSKPGRRVYSSIKDLKPIKNGLGISIL STPKGVMSDSAARDANVGGEVLCRVYMDRQNIRIRLKAFDHRVLDHSTREIVNTAKRTGATVRGPIPLPTLIEKFTVNRS PHVDKKSR-EQFEIRTHKRVLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRILEGVVVSDKGDKTVVVKVERTIVHPLLK KIVRRSKKYHAHDES--NAYKAGEVARIVECAPKSKLKTWEVLP--KAS------------------------------- -MTRSV-WKGPFVDG-YLLKKADAALA---SGRKD----VIKTWSRRSTIMPQFVGLVFGVHNGQKHVPVSVSE-DMVGM KFGEFAPTRNFPGHA------A---DK----KAK------RK >ALPHA_Dinoroseobacter_shibae_DFL_12 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKSLTEGLSKKGGRNNTGRITMRR-RGGGAKRL---- YRIVDFK-RR--K-FDVEGVITRIEYDPNRTAFIALVTYT-DGEQAYILAPQRTAVGDKVVASQ-K-AD-IKPGNAMPFS GMPIGTIVHNIELKPGKGGQIARAAGTYAQFVGR--DGGYAQIRLSSGELRLVRQECMATVGAVSNPDNSNQNLGKAGRN -RHK-----GIR-P-SVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGARTR-NKNKASS-K-LIIRSR --------------------------------MRS---G-VIAKKVGMTRLFM-EDGK---------QVPVTVLQLDKLQ VVAQR----TAE----K--DGY--SAVQLGA-------GT--ATTK----------AMRGHFA----------------- ---AS-VEPKRKVAEFRV--------APENLI-----NV---GE-EITA--D-H-YFEGQYVDVSGTSIGKGFAGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHMGAARVTTQNLQVVRTDADRG---------------- ----------LIMIKGA-VPGSKGGWVTIK--MKLDVIK-LDGEAA-GSVELDEALF----GL-EP-RADILHRVVRWQR NKAQAGTHKVKTRSE--------VS-YSTKKIY---------RQKGTGGAR--------HGA---RS-AP----IF---- RKGGIYKGPT-P-RSHAHDLPKKFRKLGLKHALSAKAKAG----------------E-LVVIDMA----TSE-------- --GKTALVI--DGAQD--A---GFAKAAANIDTLD-V---------------LPSMGANVYDILKRDT----LVLTKAGV EALEPRLKAAYAETI----RAAMKEEFGYKNDMMIPRLDKIVLNIGAGAEAVKDSKKAKSAQDDLSAIAGQRAVITKAKK SIAGFRVREDMPLGAKVTLRGDRMYEFLDRLITIAMPRIRDFRGVKG-SAFDGRGNYALGLKEHIVFPEIN-----FDKV DEVWGMDIIICTT-----------------------AASDAEAKALLKHFNMPFMSRIG-K--KPVELPTGVTAS-V--- -S-G--Q-TIEVKGPKATRSFTA--TD-D--VTLKVED-NV--ITI----E-P--RGKKRAR-QQWGMSRTMVGNLVTGV TNGFKKELEIQGVGY--RAQMQG-NT--LKLN--LGLSHEVNYEV-P-A-GVTVTCP--K-VTEIVIEG-TDEQLVGQVA ANIRDWR------KPEPY---KGKGIRYKGEFIFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SKRK Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILN-NNNE-PIGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--NELRDNPGA-TKPRKRVG-RGPGSGM-GKTGGRGIKGQKSRSGVA----- -IKGF-E-GGQMPLYQRLPK-RG--FNMVNLGLIITEDALLAS-GLIRVR---------VLA--KGE-I-T-T-K-IDL- TVTGASKSAIDAVEKAGGSV-K---QFK--GRI---RGEA-KGGSDLNFG----------TYGLKAL--QPERITARQIE AARRAMTRHM------KRQGRVWIRIFPDLPVTSKPVEVRMGKGK---------GSVDFWACKVKP-GRIMFEI--DG-- VSEPVAREALRLAAMKLPIKTRT-VKRDLFLKRRLRVRNKL--KKMADGRPRLSVHRSGKNISVQLIDD---V--QGRTL AAASSL-EKDL-------GIVGK-NNVEASAKVGAAIAER--AKKAG-IEECYFDRGGFLFH--GKVKALADAAREGGLK F-------------------------------------------------------------ENE-AMAKTRMLRTSPQK LNLVAQMIRGKKVDKALADLTFS---------------------------------HKRIAVDVKKCLQSAIAN----A- ENNH-GLDVDELIVAEAWVGKNLTMKRGRPRARGRFGKIIKPFAEITIKVRQAAKLKKGDKVVVLAGK------DK-GKE GEITSVSPKTG--KAV--VDGLNIAIRHTR--------QSQNSQ-GGRIPQAMPIDLSNLA-LVDSN--------GK--P --TRVGFRM----E--------DGKVR---FAKTTG---EVV--MGNKVNPIGMRLQ--VN-RTWDSRWYA------DTK D--YGDLLLEDLKIREFI--KEECK-----QAGISRVIIERPH-K-KCRVTIHTARPGVIIGKKGADIEGLRRKIAAMLH LNIVEVRK---PELDAALVGESIAQQLERRVSFRRAMKRAVQNAVRM-GAQGIRVNLAGRLGGAEIARTEWYREGRVPL- -HTLRADIDFANVEATTAYGIIGIKVWIF-MMNDPLGDMLTRIRNAQMRGKSTVRT-PASKLRAWVLDVLTDEGYIRGYE KVA----D---S----KHPELEISLKYY----EG-------V---PVIRELKRVSKPGRRVYMGSKDIPSVRQGLGVSIV STPRGVMSDANARTANVGGEVLCTVFIQSQNIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHVDKKSR-DQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVQISVKRILNGVVTSDANAQTVTVSVERRFTHPVLK KTIRKSKKYRAHDAE--NAFKVGDKVRIQECAPMSKTKRWEVIA------------------------------------ -MTRSV-WKGPFVDA-YVLKKAEKTRE---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGRKHIPVNVTE-DMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Ehrlichia_canis_Jake Concatenation of 2 sequences MGIKNLNSVTASLRGTVLLDKSM-LWKG------------KP-EKSLVSYKISCGGRNSRGVITVRH-RGRGHKRL---- YRIIDFK-R--NK-VGVSATVERLEYDPNRTAFIALLSYD-DGEKSYIIAPNGLKKGDVVISGE-G-SD-ILPGNCLMLK SIPVGTFVHNVELRPGNGGVIARSAGTYAQLMSK--DGVYVLLRLSSGEIRKVLSDCRATIGIVSNLDNQNVKLGKAGRN -RWL-----GIR-P-TVRGVAMNPIDHPHGGGEGKT----SGGRNPVTP---WGVPTKGKKTR-KRNKSSN-K-YIKRVS --------------------------------KRI---G-LFLEKVGHTAIFD-NEGK---------RIPVTLLHLRDSF IISTK----TKD----I--NGY--NAVVLGV-------ES---IKK----------PQLKILK----------------- ---SN-ITAKCRIFESRV--------DNLDGI-----VK---GA-KISI--T-H-FVENQYIDVTGYSLGKGFAGVMKRH NFKG-LKASHGVSIAHRS-QGSTGQC-QDPG-RVYKGKKMAGHLGSSKVTVQNLKVILVDQERS---------------- ----------LLVVKGNNIPGAKGSYVFVK--MEVSIIN-VNSDKI-GTIDLNPLIF----SV-DY-RPDILKMVVNWQL SKRRAGTHKAKTIGD--------IS-GTTAKPY---------RQKHTGRAR--------QGS---LR-SP----QF---- RGGAVIFGPV-V-RNHAYSLNKKVRKLGLKVALSLKNSCN----------------K-LLILDSI----DVN-F------ --VKTTLII---DKDN--K---NVVCSCRNLHNVT-L---------------LKQIGTNVLDILRHDC----IILTVGAV KYLE-MLKDLYKSHI----VPSLKTKLGYSNVMQVPKIVKVCLNIGLG-IRGSDSKVMNSCVRDLALIAGQKPVATYAKK SIAGFKIRKGFPIGCKVTLRNNKMYEFLERLIHVVLPREQDFKGLSV-NQFDGCGNLSIGIKEHISFLEID-----YDKI DKILGLDINIVTN-----------------------AVNNNDAKLLLMEFGFPFMSRVG-S--MPIAIPSNVQVD-L--- ---V-GN-QLILKNSENSLKLNL--NH-N--VLCDITD-GK--IVL---RV-N--DKSIKSK-VIWGTYRSIINNYAIGL SQGVVVELEVNGVGY--KAEING-EY--LSLF--LGFSHGIKYKI-P-K-GIVIQCV--K-PTQILVKG-FDKQKVYMVA SDICSIR------KYNPY---KGKGISIKGKYVHRKEVN----------MIQKNTLLDVADNSGARKVLCIGLL---GKK S--ASVGDVIVVSTKVITPR-G-------KVSKGKVYKAVVVRVKKAVRRLDGSIIRFSSNAVVLIN-DQGD-PLGTRVF GPI-KKLP-FGLFSKVMSLAVEVLVK-L--NNIFSGLPK-KKKTKVLG-RGIGCGK-GKTSGRGHKGQKARSGVS----- -INGF-E-GGQQSIFTRLPK-RG--FNSVNLSTIITKQVLFNL-GVIPIK---------ILG--DGK-L-N-T-A-VAI- EYDFISKSAGSQVTLLSSVS-K---DFK--GRI---SGNA-KGGYTLSFG----------SYGLKAL--EPCRLTSKQIE SARRSISRTL------KRVGKVWIRAFCHTSVSKKPMDVRMGKGK---------GSVEMWVCKVKP-GKILFEI--SG-- VSLNLAREALNKAQAKLPMKCKF-VCITRSERRKKRVRLKL---RRNSSLLRLSIFKSNRHFYVQLIDD---K--CGRTF ASASTL-ESEV-IAVT----NRK-VNSNAVKIVAKLMSDR--LNKLGNCKKFVFDRGPYKYT--GIVSEFANELRNYGFE I-------------------------------------------------------------GKVLVEAKGIGLRSTPSK LNLVADLIRGKDVSVAMMYLKFC---------------------------------KKKSAGYISKVLKSAVAN----A- QANY-NVDLDNLYVKEVLVGKSFSLRRVHARARGKACRVHKHYGNVIIKLFEGMKIVVGDDVVVISGK------DK-GKM GKVIKVLRKKHFGKAI--VSGVNICKKSVK----AT--QK--SD-GGIINIAKPINLSNIA-LFDSTL-------GI--R --TRVGYKF---ID--------EKKVR---FMKSSG---KVI--MGQKCNPIGLRLK--II-NTWDSLWYA------N-K D--YTTKLHEDFLLRKFI--KKAFY-----HAAISKVVIARKV-D-LIMVNVYSAKPGVIIGKKGADIDKVKQQIVKMIE LNIIEVKK---PELKAVLIAENIAQQLEKRISFRRAMKRSVQNCLKI-GAKGIKVSCAGRLGGAEIARTEWYKEGSVPL- -HTFRANIDYGFSEAKTIYGIIGVKVWVYMSLSDPIANFLTSIRNGQLSMNKVIVV-SYSYVIHAILQILLSEGYIDGFT EKS--KSS--------SIKFFEVKLKYY----NG-------A---PVISQIARISKPGKRCYCSAKDMPKFYNGLGLYII STSKGIMSDYNARKAGVGGEILCGVFMVTQKIYIELKAFDSCLLDRSARSIILTAKRSGARVNGPIFFPRKVMKFIVNRS THVDKKSR-EQFEIRTHKRLISLPRANSTIIQALMSLQLPAGVDVKVKVKKVLTGVVVATKCDKTIKVMVSRMVRHKTYK KIVKKRKNYVVHDEY--NKCKCGDVVKIQEHIPISATKRWIVI------------------------------------- -MSRSI-KKPPFCAP-HVLRLVNKAVA---QNKLN---SIINIHSRSSVILNKFIGLTFGVYNGKTYVPVKVND-NMVGR KFGEFSPTRRYTGHV------G---DK----KVS------RK >ALPHA_Ehrlichia_chaffeensis_Arkansas Concatenation of 2 sequences MGIKNLNSVTASLRGTVLLDKSM-LWKG------------KP-EKSLVSYKISRGGRNSRGVITVRH-RGRGHKRL---- YRVVDFK-R--NK-VGVSATVERLEYDPNRTAFIALLSYD-DGEKSYIIAPNGLKKGDVVISGD-G-AD-ILPGNCLLLK SIPVGTFVHNVELRPGNGGVIARSAGTYAQLMSK--DGMYVLLRLSSGEIRKVLSDCRATIGIVSNLDNQNVKLGKAGRS -RWL-----GIR-P-TVRGVAMNPIDHPHGGGEGKT----SGGRNPVTP---WGVPTKGKKTR-KRNKSSN-K-YIKRVS --------------------------------KRI---G-LFLEKVGHTAIFD-NEGK---------RIPITLLHLRDSF IISKK----TKD----I--HGY--DAVVLGV-------EA---LKK----------PQSKILK----------------- ---SK-ITAKCKIFESRV--------DNLGDV-----VE---GA-KVSI--T-H-FVKDQYVDITGYSLGKGFAGVMKRH NFKG-LKASHGVSIAHRS-QGSTGQC-QDPG-RVYKGKKMAGQLGNSKVTVQNLKVILVDQERS---------------- ----------LLGVRGNNIPGAKGSYVFVK--MEVNIIN-VNSDRI-GTIDLNPLIF----SV-NY-RPDILKMVVDWQL SKRRAGTHKAKTIGD--------IS-GTTAKPH---------RQKHTGRAR--------QGS---LR-SP----QF---- RGGAVIFGPV-V-RSHAYSLNKKVRNLGLKVALSLKNSCN----------------K-LLILDSI----DVN-F------ --VKTTLII--DKDYN--K---SVVCSCRNLHNVT-L---------------LKQIGTNVLDILRHDC----IILTVGAV KYLE-MLKDLYKSHI----VPSLKTKLGYSNVMQVPKIVKVCLNIGLG-IRGSDSKVMNSCVRDLALIAGQKPVATYAKK SIAGFKIRKGFPIGCKVTLRNNKMYEFLERLIHVVLPREQDFKGLSV-SQFDGCGNLSIGIKEHISFLEID-----YDKI DKILGVDINIVTN-----------------------AVNNNDAKLLLMEFGFPFMSRVG-S--MPIAIPSNVQADLV--- ---G--N-QLILKNNENSLKLTL-DYG----VLCDITD-GK--IVL----H-V--NDKIKSR-VMWGTYRSIINNYAIGL SQGLVVELEVNGVGY--KAEVNG-EY--LSLS--LGFSHGVKYKI-P-T-GIVIQCV--K-PTQILVKG-FDKQKVYMVA SDICSIR------KYNPY---KGKGISIKGRYVHRKEVN----------MIQKNTLLDVADNSGARKVLCIGLL---GKK S--ASVGDVIVVSTKLITPR-G-------KVSKGKVYKAVIVRVKKAVRRLDGSVIKFSSNAVVLIN-DQGD-PLGTRVF GPI-KKLP-FGLFSKVMSLAVEVLVK-L--NNIFSGLPK-NKKSKVLG-RGIGCGK-GKTSGRGHKGQKARSGVS----- -INGF-E-GGQQSIFTRLPK-RG--FNSVNLSTIITKEVLYNL-GVISIK---------ILG--NGK-L-N-T-A-VAI- EYDFISKSAESQVTLLSNVS-K---DFK--GRI---SGNA-KGGYTLSFG----------SHGLKAL--EPSRLTSKQIE SARRSISRTL------KRVGKVWIRAFCHTSVSKKPMDVRMGKGK---------GSVEMWVCKVKP-GKILFEI--GG-- VPLNLAREALNKAQAKLPMKCKF-VCGTRLERRKKRVRLKL---KRNSSLLRLSIFKSNRHFYVQLIDD---K--CGRTF ASASTL-EREV-VALT----NRR-VNSDSVKIVAKLMSDR--LNKLDNCKKFIFDRGLYKYT--GIVSEFANELRSYGFE F---------------------------------------------------------------M-IVAKGMGLKSTPSK LNLVADLIRGKDVSVAMMYLKFC---------------------------------RKKSAGYISKVLKSAVAN----A- QANY-NIDLDNLYVKEVLVGKSFSLRRIHARARGKACRVYKHYGNVIIKLFEGMKIIAGDDVIVISGK------DK-GKM GKVIKVLKKKHCGKAI--VSGVNVCRKSVK----AT--QK--SD-GGIISVEKPINLSNIA-LFDSTL-------GI--Q --TRVGYKF---IG--------EKKVR---FMKSSG---KVI--MGQKSNPIGLRLK--II-NTWDSLWYA------N-K D--YTTKLHEDFLLRKFI--KKAFY-----HASISKVVIARKV-D-VIMVNVYSAKPGVIIGKKGADIDKVKQQIVKMIE LNIIEVKK---PELKAVLIAENIAQQLEKRISFRRAMKRSVQSCLKI-GAKGIKVSCAGRLGGAEIARTEWYKEGSVPL- -HTFRANIDYGFSEAKTIYGIIGVKVWVYMSLSDPIANFLTSIRNGQLSMNKVIVV-SYSYVIHAILQILLSEGYIDGFT EKS----K---G---SNIKFFEVKLKYY----NG-------A---PVISQIARISKPGKRCYCSAKDMPKFYNGLGLYII STSKGIMSDYNARKSGVGGEILCGVFMVTQKIYIELKAFDSCLLDRSARSIILTAKRSGARVNGPIFFPRKIMKFIVNRS THVDKKSR-EQFEIRTHKRLISLPKANSTIIQALMSLQLPAGVDVKVKVKKVLTGIVVDAKCDKTIKVMVSRMIMHKTYK KIVKKRKNYVVHDEH--NQYKCGDVVKIQEHIPISATKRWIVI------------------------------------- -MSRSI-KKPPFCAP-HVLRLVNKAIA---QNKLN---SIINIHSRSSVILNKFIGLTFGVYNGKTYVPVKVND-NMVGR KFGEFSPTRRYTGHV------G---DK----KVS------RK >ALPHA_Ehrlichia_ruminantium_Gardel Concatenation of 2 sequences MGIKNLNSVTPSLRGTVLLDKST-LWKG------------RP-EKSLVGYKISHGGRNSRGVITVRH-RGKGHKRL---- YRIIDFK-R--KK-VGVPATVERLEYDPNRTAFIALLSYD-DGEKSYIIAPHGLKKGDVIMSGN-G-SD-ILPGNCLMLK LIPVGTFVHNVELRPGGGGIIARSAGTYAQLMSK--DGIYVLLRLSSGEIRKVLADCCATIGIVSNLDNQNVKLGKAGRS -RWL-----GIR-P-TVRGVAMNPIDHPHGGGEGKT----SGGRNPVTP---WGVSTKGKKTR-KKNKSSN-K-YIKRVS --------------------------------KRI---G-LLLEKVGHSAIFD-NEGK---------RIPVTLLHLRDSF VVSIK----DKD----S--HGY--TSVVFGM-------KV---MKK----------PQLKILK----------------- ---SN-INVNCKIFESRV--------DHIDNL-----VV---GA-KVLI--T-H-FVENQYVDITGHSLGKGFAGVMKRH NFKG-LKASHGVSISHRS-QGSTGQC-QDPG-RVYKGKKMAGHLGNSKVTVQNIKVISVDKEKS---------------- ----------LLVVKGNNIPGAQGSYLFVR--MEVNVIN-IESQNI-GKIDLNPLIF----SV-NY-RPDILKMVVEWQL SKRRVGAHKTKTIGD--------VS-GTTAKPY---------RQKHTGRAR--------QGS---LR-SP----QF---- RGGAVIFGPV-V-RSHAYSLNKKVRNLGLKVALSLKNSCN----------------K-LLILDSI----DVN-F------ --VKTALII---GKDN--K---GMMYSCKNLHNVT-L---------------LKQIGTNVFDILRHDC----VILTVDTV KYLE-MLKDLYKTQI----VPSLQNKLGYSNVMQVPKIVKVCLNMGLG-IRGSDSKVMNSCVRDLALIAGQKPVATSVKR SIAGFKIRKGFPIGCKVTLRNNKMYEFLERLIYVVLPREQDFKGLSI-NQFDGCGNISIGIKEHISFLEVD-----YDKI DKILGLDINIVTN-----------------------AVNNKDAKLLLMEFGLPFMSRVG-S--MPILIPSNVQVD-L--- ---V-GN-QLTLKNSENSLKLVL--DY-G--VSCNIDG-NS--ITL---HV-N--DSSANSR-VMWGTYRSMINSYAIGL SQGLVVELEITGVGY--KAEVND-EY--LSLS--LGFSHGIKYKI-P-N-GIIIQCV--K-PTQILVKG-FDKQKVYMVA SDICSIR------KYNPY---KGKGISIKGKYIYRKEVN----------MIQKNTLLDVADNSGARKVLCIGLL---GKK S--ASVGDVIVVSTKVVIPR-G-------KVSKGKVYKAVIVRVKKAVRRLDGSVIKFSSNAVVLIN-DQGD-PLGTRVF GPV-KKLP-FGLFSKVMSLAVEVLMK-L--NNIFSGLPK-KKKSKVLG-RGIGCGK-GKTSGRGHKGQKARSGVS----- -INGF-E-GGQQSIFTRLPK-RG--FNSINVSLIITKEVLYNL-GVISIK---------ILG--DGK-L-N-T-T-VCI- EYDFISKSAKSQVTLLNSLS-K---DFK--GRI---SGNA-KGGYTLAFG----------TYGLKSL--EPGRLTSKQVE SARRSISRTL------KRVGKVWIRVFCHTPVSKKPMDVRMGKGK---------GSIEMWVCKVKP-GKILFEI--SG-- VSLNLAKEALQKSQAKLPVKCKF-ITSNRFERRKRRVRLKL---KNNLSLLRLSIFKSNRHFYVQLIDD---S--CGKTY AAASTL-EREV-IALA----HRR-VNSNSVKIVAKLMSER--LNKLDNCKKFVFDRGPYKYI--GVVAEFANELRSYGFE F-------------------------------------------------------------SKVLVEAKGMGLRSTPYK LNLVADLIRGKPVSVAVMYLKFC---------------------------------KKKSARYISKVLKSAIAN----A- QANY-SVDVDNLYIKEVLVGKSFSLRRIHARARGKACRVYKHYGNVIIKLFEGMKIIAGDDVLVVSGK------DK-GKM GKVIKVLKKKSCGKAI--VSGINICKKSVK----AT---Q-NSD-GGIISVERPINISNIA-LVDSVL-------GI--R --TKVGYKF---ID--------DKKVR---FMKSSG---KVIF-MGQKSNPIGLRLK--II-NTWDSLWYA------N-K D--YTTKLHEDFLLRKFI--KKAFY-----HASISKVVIARKV-D-VIMVNVYSAKPGVIIGKKGADIDKVKQKIVKMIE LNIIEVKK---PELKAILIAENIAQQLERRVSFRRAMKRSVQSCLKI-GAKGIKVSCAGRLGGAEIARTEWYKEGSVPL- -HTFRANIDYGFSEAKTIYGIIGVKVWVYVSLSDPIANFLTSIRNGQLSMNKVVTV-SYSYVIHAILQILLSEGYIDGFT EKL-RS-T-N-------IKFFEVKLKYY----NG-------V---PVINRICRVSKPGKRCYCSAKGMPKFYNGLGLYII STSKGIMSDYNARKSGVGGEILCGVFMVTQKIYIELKAFDSYLLDRSARSIILTAKRSGARVNGPIFFPRRVAKFIVNRS THVDKKSR-EQFEIRTHKRLISLPKANSTIIQALMSLQLPAGVDVKVKVKQVLTGVVVGAKCDKTIKVMVSRMVSHKMYK KIVKKRKNYVVHDEY--NRYKCGDVVQIREHIPISATKRWVVI------------------------------------- -MSRSV-KKPPFCAP-HVLRLVNKAIA---QNKLN---SIINIHSRSSVILNKFIGLTFGVYNGKTYVPVKVND-NMIGR KFGEFSPTRRYTGHV------G---DK----KVS------RK >ALPHA_Ehrlichia_ruminantium_Welgevonden_(ARC-OVI) Concatenation of 2 sequences MGIKNLNSVTPSLRGTVLLDKST-LWKG------------RP-EKSLVGYKISHGGRNSRGVITVRH-RGKGHKRL---- YRIIDFK-R--KK-VGVPATVERLEYDPNRTAFIALLSYD-DGEKSYIIAPHGLKKGDVIMSGN-G-SD-ILPGNCLMLK LIPVGTFVHNVELRPGGGGIIARSAGTYAQLMSK--DGIYVLLRLSSGEIRKVLADCCATIGIVSNLDNQNVKLGKAGRS -RWL-----GIR-P-TVRGVAMNPIDHPHGGGEGKT----SGGRNPVTP---WGVSTKGKKTR-KKNKSSN-K-YIKRVS --------------------------------KRI---G-LLLEKVGHSAIFD-NEGK---------RIPVTLLHLRDSF VVSIK----DKD----S--HGY--TSVVFGM-------KV---MKK----------PQLKILK----------------- ---SN-INVNCKIFESRV--------DHIDNL-----TV---GA-KVLI--T-H-FVENQYVDITGCSLGKGFAGVMKRH NFKG-LKASHGVSISHRS-QGSTGQC-QDPG-RVYKGKKMAGHLGNSRVTVQNIKVISVDKEKS---------------- ----------LLVVKGNNIPGAQGSYLFVR--MEVNVIN-IESQNI-GKIDLNPLIF----SV-NY-RPDILKMVVEWQL SKRRIGAHKTKTIGD--------VS-GTTAKPY---------RQKHTGRAR--------QGS---LR-SP----QF---- RGGAVIFGPV-V-RTHAYSLNKKVRNLGLKVALSLKNSCN----------------K-LLILDSI----DVN-F------ --VKTALII--GKDYN--K---GMMYSCKNLHNVT-L---------------LKQIGTNVFDILRHDC----VILTVDTV KYLE-MLKDLYKTQI----VPSLQNKLGYSNVMQVPKIVKVCLNMGLG-IRGSDSKVMNSCVRDLALIAGQKPVATSVKK SIAGFKIRKGFPIGCKVTLRNNKMYEFLERLIYVVLPREQDFKGLSI-NQFDGCGNISIGIKEHISFLEVD-----YDKI DKILGLDINIVTN-----------------------AVNNKDAKLLLMEFGLPFMSRVG-S--MPILIPSNVQVDLV--- ---G--N-QLTLKNSENSLKLVL-DYG----ISCNIDG-NS--ITL----H-V--NDSANSK-VMWGTYRSMINSYAIGL SQGLVVELEITGVGY--KAEVND-EY--LSLS--LGFSHGIKYKI-P-N-GIIIQCV--K-PTQILVKG-FDKQKVYMVA SDICSIR------KYNPY---KGKGISIKGKYIYRKEVN----------MIQKNTLLDVADNSGARKVLCIGLL---GKK S--ASVGDVIVVSTKVVIPR-G-------KVSKGKVYKAVIVRVKKAVRRLDGSVIKFSSNAVVLIN-DQGD-PLGTRVF GPV-KKLP-FGLFSKVMSLAVEVLMK-L--NNIFSGLPK-KKKSKVLG-RGIGCGK-GKTSGRGHKGQKARSGVS----- -INGF-E-GGQQSIFTRLPK-RG--FNSINLSLIITKEVLYNL-GVISIK---------ILG--DGK-L-N-T-T-VCI- EYDFISKSAKSQVTLLNSLS-K---DFK--GRI---SGNA-KGGYTLAFG----------TYGLKSL--EPGRLTSKQVE SARRSISRTL------KRVGKVWIRVFCHTPVSKKPMDVRMGKGK---------GSIEMWVCKVKP-GKILFEI--SG-- VSLNLAKEALQKSQAKLPVKCKF-ITSNRFERRKRRVRLKL---KNNLSLLRLSIFKSNRHFYVQLIDD---S--CGKTY AAASTL-EREV-IALA----HRR-VNSNSVKIVAKLMSER--LNKLDNCKKFVFDRGPYKYI--GVVAEFANELRSYGFE F-------------------------------------------------------------SKVLVEAKGMGLRSTPYK LNLVADLIRGKPVSVAVMYLKFC---------------------------------KKKSARYISKVLKSAIAN----A- QANY-SVDVDNLYIKEVLVGKSFSLRRIHARARGKACRVYKHYGNVIIKLFEGMKIIAGDDVLVVSGK------DK-GKM GKVIKVLKKKSCGKAI--VSGINICKKSVK----AT---Q-NSD-GGIISVERPINISNIA-LVDSVL-------GI--R --TKVGYKF---ID--------DKKVR---FMKSSG---KVI--MGQKSNPIGLRLK--II-NTWDSLWYA------N-K D--YTTKLHEDFLLRKFI--KKAFY-----HASISKVVIARKV-D-VIMVNVYSAKPGVIIGKKGADIDKVKQKIVKMIE LNIIEVKK---PELKAILIAENIAQQLERRVSFRRAMKRSVQNCLKI-GAKGIKVSCAGRLGGAEIARTEWYKEGSVPL- -HTFRANIDYGFSEAKTIYGIIGVKVWVYMSLSDPIANFLTSIRNGQLSMNKVVTV-SYSYVIHAILQILLSEGYIDGFT EKL-RSTN-I-K-------FFEVKLKYY----NG-------V---PVINRICRVSKPGKRCYCSAKGMPKFYNGLGLYII STSKGIMSDYNARKSGVGGEILCGVFMVTQKIYIELKAFDSYLLDRSARSIILTAKRSGARVNGPIFFPRRVAKFIVNRS THVDKKSR-EQFEIRTHKRLISLPKANSTIIQALMSLQLPAGVDVKVKVKQVLTGVVVGAKCDKTIKVMVSRMVSHKMYK KIVKKRKNYVVHDEY--NRYKCGDVVQIREHIPISATKRWVVI------------------------------------- -MSRSI-KKPPFCAP-HVLRLVNKAIA---QNKLN---SIINIHSRSSVILNKFIGLTFGVYNGKTYVPVKVND-NMIGR KFGEFSPTRRYTGHV------G---DK----KVS------RK >ALPHA_Erythrobacter_litoralis_HTCC2594 Concatenation of 2 sequences MALKNYNPTSPARRGLILVDKSG-LYKG------------KP-VKSLTEGKRKTGGRNNKGHVTSRG-IGGGHKQK---- YRYIDFK-R--RK-WDVEGTVERIEYDPNRTAFIALVKYD-DGELAYIIAPQRLAVGDKVIAAE-K-AD-TKPGNAMLLG QMPVGTICHNVEMKPGKGGQIARSAGAYVQLVGR--DRGMVIVRLNSGEQRYLRADCMGTVGAVSNPDNQNQNLGKAGRR -RWM-----GVK-P-LTRGVAKNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGARTR-KNKQ-TD-K-FIIRSR --------------------------------MRT---G-VIAKKVGMTRLFQ-EDGR---------HVPVTVLALEDCQ VVSQR----TQE----R--DGY--FALQVGS-------GV--AVAK----------PQREAFK----------------- ---AE-VGLKMKVAEFRV-------EGEDGLL-----PV---GA-AISA--E-H-FIAGQKVDITGYTQGKGFAGAMKRW GFGG-LRATHGVSISHRS-HGSTGNR-QDPG-RVFKGKKMAGHMGDRQRTQQNLEVVRTDPERG---------------- ----------LIFVKGS-VPGTKNSWMLIR--MKVKVQK-IDGKAA-GDVELDDAVF----GV-EP-RADILHRVVTWQL ENRRGTARPTRERSD--------VA-RTGAKFG---------RQKGSGNAR--------HGD---RG-AP----IF---- IGGGKAHGAR-K-RDFNPSLNKKIRALGLKMALSSKAKDG------------------LVVVDSL----DLK-D------ --AKTKLVI--DESVN--E---GFSKAAGNLPGVN-V---------------LPAMGANVYDILKHDT----LVLTKDAV EKLE--MKARYENEI----VKAMTEKFGYKNRLEVPRLEKITLNMGVG-EASQDKKKVQTAAEEMALIAGQKPVITKAKK SIAQFKLREGMPIGCKVTLRRDRMFEFLDRLVTIAMPRIRDFRGLNA-KSFDGRGNYAMGLKEQIIFPEIS-----YDKI EKVRGMDIIVTTT-----------------------AKTDEEARELLRLFGFPFMSRIG-K--RAVAIPSGVEAK-I--- -D-N--G-TLTVKGPKGTLSLGL--SD-L--IDYKIEG-DE--IAV----N-P--ANDQKAR-SYWGMQRTLVSNLVEGV TEGFSKTLEISGVGY--RAQAQG-KT--LKLQ--LGYSHDVDIAV-P-E-GLEVKTP--D-QTTVIISG-IDKQAVGQLA AEIRQWR------KPEPY---KGKGIKYQGEYVFRKEGK----------MIQMQSNLDVADNSGAKRVQCIKVLG-SKRR T--ASVGDVIVVSVKEAQPR-A-------KVKKGDVHRAVIVRTKKDVRRPDGSVIRFDSNAAVLVS-KNEE-PIGTRIF GPVVRELR-GRGFMKIISLAPEVLMK-L--NDLRDNEGA-RKGRIRVG-RGIGSGK-GKTGGRGQKGQKSRSGVA----- -IKGF-E-GGQMPLHMRLPK-RG--FNNVNIGMVITEEALREA-GLVRVR---------LLG--KGE-L-K-A-K-VKF- IVAGASKGAVEAVEKAGGSV-K---AFK--GRI---KGDA-KGGTTLNFG----------SYGLKAL--EPERVTARQIE AARRAITRHI------KRQGRLWIRVFPDVPVSKKPAEVRQGKGK---------GSVEYWAARVKP-GRILFEL--DG-- VPGPLAASAFERAAMKLPVKTKV-VKLSLFERRRQRVRSAL--RKRSGDKPRLSVHRTGKHIYAQVIDD---A--DGKTL AAASTL--GAK---------GSG-ANVDAAAKVGKDIAAA--AKKAG-VTTVVFDRGGFLFH--GRVKALADAAREGGLE F-------------------------------------------------------------DNE-ALAVGTTIRGSAQK LNLVAELIRGKKAEEALNILAFS---------------------------------KKAMARDASKVLASAIAN----A- ENNH-DLDVDALVVAEASVGKSITMKRFHTRGRGKSTRILKPFSKLRIVVRESAKIKKGDSVVVLSGK------DK-GKT GTVAKVMPKEG--KVV--VEGVNMIARHRK----PS--QE-NPQ-GGIDRYEAPMHIAKVA-VADPKD-------GK--P --TRVRIEE----K--------DGKVR---VAVKSG---ETI--MGQKSNPIGLRLQ--IN-RTWDSRWYA------EGN A--YAKLLAEDIEIRKYI--LETAA-----QAAISKVVIERPA-K-LCRISIYAARPGVIIGKKGADIEKLRQKLSTMVK LNIVEIRK---PEIDAKLVAQGIADQLIRRVAFRRAMKRAMQSAMRL-GAEGIKIVCGGRLGGAEIARVEQYREGRVPL- -HTLRANIDYAEAEALTAYGIIGIKVWVFMAMTDPLGDMLTRIRNGQQAKKDSVLS-PASKLRANVLEVLQREGYIRGYS EDA----S---G----KHAALRIELKYF----EG-------E---PAIKHVARVSKPGRRIYSGSKELPTVRNGLGITIV STPKGVLSDNEARTQNVGGEVLAEVFMEAQNIRIRLKAFDHRVLDQATGEIADTARRTGALIRGPIPMPTRIEKFTVNRG PHIDKKSR-EQFEVRTYKRLLDIVQPNAQTVDALMKLDLAAGVNVEIKLKRILIGTVTSDKTDKTVTVLVERKVKHPLYG KIIRRSKKYHAHDEK--NEYTLGDVVRIEETKPISKTKTWAVKDRVVAG------------------------------- -MARSV-WKGPFVEL-SLLRKAEDAQE---ASSNK----PIKTWSRRSTILPQFVGLTFNVYNGHKFIPVSVSE-EMVGH KLGEFAPTRTFPGHA------A---DK----KGK-------R >ALPHA_Gluconacetobacter_diazotrophicus_PAl_5 Concatenation of 2 sequences MALKHFNPVTPSLRGTVLIDRKE-LWKG------------KP-VKGLTEGKNKSGGRNNHGRTTSRF-IGGGHKQS---- YRYVDFK-R--RK-FDVVGTVERLEYDPNRTAFIALVKYE-DGELAYILAPQRLKAGDQVVAGA-R-VD-IKPGNAMPLS AIPVGTIVHNIELKQGAGGKMARSAGTYAQLVGK--DSGYAQIKLQSGELRVVRGECMATIGAVSNPDNMNQHMGKAGRS -RWL-----GRR-P-HNRGVVMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGYKTR-VNKRTDS---LIIRRR --------------------------------MRT---G-LIAKKLGMTRLFK-EDGT---------HVPVTVLHVDNLQ VVDVR----TQD----R--DGY--TAVQLGF-------GN--AVSK----------PNRGHFR----------------- ---VK-VEPKKKLAEFRV--------ADDAVL-----EA---GA-TLSA--A-H-FVVGQKVDVTSTSKGKGFAGAMKRW NFAG-LEASHGVSISHRS-HGSTGNR-QDPG-KTFKNKKMAGHLGSERVTTLNLEVAAVDAEKN---------------- ----------LLMVRGS-VPGGKNELVLVR--MDYEIKT-LDNGSA-GTAVLPDEIF----GV-TP-RADIMARVVHWQL AKRRAGTHKVKGMGE--------VS-GTTKKPY---------RQKGTGSAR--------QGS---LR-AP----QY---- RTGGAVHGPV-V-RDHGYDLPKKVRRLGLISALSQKAAEG----------------K-LVVLDAA----TAS-------- --GRTSLIV--DATVE--E---NFGRAARNLPKID-A---------------LPTIGANVYDILNHDV----LAITRAGV EGLKPRLQKRFQDEL----RAKLREEFGYKNVMQVPHLEKIVINMGVG-EAAGDQKKLDAALGEMTLISGQKPVKTVAKK AIAGFKIRAGLPIGCKVTLRRARMYEFLDRLVTIALPRVRDFRGLPGNKGFDGRGNFAMGLKEQIIFPEIE-----YDKV DDIRGMDIIFVTS-----------------------AKTDAEAKALLKAFDLPFMSRVG-K--YPVEVPSGVQVS-I--- -V-D--G-IFVAKGKLGELKLPL--SQ-H--IEAEIAD-NK--VSV----R-P--VGTAPAR-MMWGTTRALVASMVKGV SEGFSKTLEVTGTGY--RAAVQG-SN--LVMN--LGYSHDIVYAI-P-A-GIKITTP--R-PTAIVVEG-VDKQRVGQVA LDIRSFR------KPEPY---KGKGVRYDTETIRRKEGK----------MIHPETNLDVADNSGARQVQCIKVLG-SKRK T--ASVGDVIVVSVKEAIPR-G-------KVKKGDVHQAVIVRTSYPVRRADGSAIRFDRNAAVLIN-KQQE-PIGTRIF GPVVRELR-ARKFMKIISLAPEVLMN-L--NELRDNAGS-RYRKKRLG-RGIGSGK-GKTSGKGVKGQKAREGVS-L--- --NGF-E-GGQLPLYRRLPK-RG--FKNVNLGALVTEDVLRTA-GLVGVR---------LLA--KGE-L-A-R-A-VTI- EVSGASATAVAAVEKAGGSV-K---AHK--GRI---HGLA-KGGTTLNFG----------AFGLKAL--EPERVTARQIE ASRRAITRAM------KRAGRVWIRIFPDLPVSTKPAEVRMGSGK---------GSPEYWVARVKP-GRILFEI--EG-- VPPELARQALALGAAKLPIKTKF-VQQDLRERRRQRLRFQL--RRKGGGRPRLSVFRSGKNIYAQVIDD---V--AGRTL AAASSL-DKAL-REQL----KTG-ADSDAAVAVGKLVAER--AVAAG-VSLVVFDRGSYMYH--GRIKALAEAAREGGLA F-------------------------------------------------------------ETE-AQALTRNIRVSPRK LNLVAGLIRNKPASQAVAILTFS---------------------------------KRRIAQDVRKTLESAIAN----A- ENNH-QLDVDQLVVVRAEVGKSIVMRRFHARGRGRSSRIEKFFSHLKIVVAEAARIKKGDQVVVITGS------SK-GSR GEVLSVRPDDN--KAV--VRGVAVAKRHTR----PN--RM-GEQ-GGIIEKEMPIHLSNLK-LVDPKS-------GK--P --TRVGFRI---LE--------DGKVR---VAKATG---EVV--MGHKVNPIGLRLG--IN-RTWDSRWYA------G-A D--YSRLLHDDLKLRAHL--RRKLS-----GAGVSRVVIERPA-K-KPRVTIYAARPGVVIGKKGQDIDVLRKDLTRMVA LNIVEIRK---PEIDATLVAENIAQQLERRVAFRRAMKRAVQSAMRL-GAQGIRINCGGRLGGAEIARVEWYREGRVPL- -HTLRADIDYGVATAKTTYGTCGVKVWIFMSLSDPLGDMLTRIRNAQRARHAACVA-PASKLRANVLEALRREGYIRGYA QED--LRK--------GVAQLRIELKYL----DG-------E---PVIKEIHRVSKPGRRVYSKIKELPRVYAGLGVSIL STPRGVLSDAEARAANVGGEVLCRVFMDNQNIRIRLKAYDHRVLDNSTKEIVNTAKRTGARVRGPIPLPTHIEKFTVNRS PHVDKKSR-EQFEIRTHRRLLDIVEPTPQTVDALMKLDLAAGVDVEIKL-------MTSDKMDKTVTVLVDRRVIHPLYK KFIRRSKKYAAHDEL--NECKIGDMVRIEECKPISKRKTWTVVVRNGAA------------------------------- -MARSV-WKGPFVDG-YLLNKADASRA---SGRSE----VIKIWSRRSTILPQFVGLTFGVYNGHKFLPVQVSE-NMVGH KFGEFSPTRTFTGHS------S---DK----KAK------RG >ALPHA_Gluconobacter_oxydans_621H Concatenation of 2 sequences MALKHFNPTTPSTRGTVLIDRSE-LFKG------------KP-VKQLTEGKNKSGGRNNHGRTTVRF-RGGGHKQS---- YRYVDFK-R--RK-FDVAATVERLEYDPNRTAFIALIKYE-DGELAYILAPQRVKVGDRVISGA-H-TD-VKPGNAMPLG AMPVGTIVHNIELKQGAGGKLARSAGTYAQLVGK--DAGYAQVKLQSGELRLVRGECMATVGAVSNPDNMNQHMGKAGRS -RWL-----GRR-P-HNRGVVMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-VNKK-TD-S-LIIRRR --------------------------------MRT---G-LIAKKLGMTRLFK-EDGT---------HVPVTVLHLDNVE VVDAR----TNE----R--DGY--TAIQLGL-------GN--AVTK----------ANRGHFR----------------- ---TK-VEPKRHLAEFRV--------SEDALL-----EA---GT-KLSA--A-H-FVVGQKVDVTGQSKGKGFAGVMKRH NFAG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGDERVTTLNLEIAAVDEERN---------------- ----------LIMVRGA-IPGAKNGLVLIR--MEYDIKT-LDNGSA-GSVALPEEIF----AV-TP-RSDIMARVVHWQL AKRRAGTHRTKGMGE--------IS-GTTKKPY---------RQKGTGSAR--------QGS---LR-AP----QF---- RTGGVVHGPV-V-RDHGYDLPKKVRRLGLICALSQKAAEG----------------K-LIVLDAA---NGV--------- --TKTRLIV--DGAVD--E---QFARAIANLPKID-V---------------LPTIGANVYDILNHDV----LVITRAGL EGLKPRLHQRYEDVL----KKQLREQFGYANELQVPKLEKIVLNMGVG-EAAGDQKKLDAAVAEMTVISGQKPVKTLARK AIAGFKIREGLPIGCKVTLRRARMYEFLDRLVTIAMPRIRDFRGLPANKGFDGHGNFAMGIKEQIVFPEIE-----YDKI DAVRGMDIIFVTS-----------------------AKSDAEAKALLKAFDLPFMSRVG-K--YPVEVPAGVQVS-V--- -ADG----FFKAKGKLGELTVPV--SR-H--VEVKIEG-SN--VSV----A-PVGRRSRENW-TMWGTTRALIANTVKGV SDGFSKGLEIQGTGF--RAAVQG-SN--LVMN--LGFSHDVVYPI-P-E-GIKITTP--R-PTAIVVEG-NDKQRVGQVA LDIRSFR------KPEPY---KGKGVRYETEVLRRKEGK----------MIHPETNLDVADNSGARRVQCIKVLG-SKRK T--ASVGDVIVVSVKEAIPR-G-------KVKKGDVHQAVIVRTSYPVRRADGSAIRFDKNAAVLLN-KQQE-PIGTRIF GPVVRELR-ARKFMKIISLAPEVLMN-L--NELRDNEGS-RYRKKRLG-RGIGSGK-GKTSGRGVKGQKAREGVS-L--- --NGF-E-GGQLPLYRRMPK-RG--FVNVNLGAIVNEEALRKA-GLVNVR---------LLA--HGE-L-S-H-G-VTI- EVAGASAAALAAVEKAGGTV-K---AHK--GRI---HGLA-KSGTQLNFG----------AFGLKAL--EPERITARQIE ASRRAITRAM------KRAGRVWIRIFPDTPVSTKPAEVRMGSGK---------GNPEYWAARVKP-GRILFEI--EG-- VPPEVAKLALSLGAAKLPIKTKF-VQQGLQERRRQRLRFQL--RRKSGGRPRLSVFRSSKHIHAQIIDD---A--QGRTL ASASTL-EKTL-RDAG----KTG-ADVSAATVIGKLIAER--GVAAG-VKTVVFDRGSYLYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DTE-AQAVARNIRVSPRK LNLVAAMIRNQPADKAIAALTFS---------------------------------RRRIAQQVKKTLESAVAN----A- ENNH-QLDVDQLVVKTAEVGKSIVMKRFHARGRGRSARVEKFFSHLKIVVAEAARIKKGDQVLVLSGK------SR-GVR GEVLAVMPKAE--KAV--VRGVAVAKRHTK----PN--RM-GGE-GGIIEREMPIHLSNLK-LVDPKS-------GK--P --TRVGFRI---LE--------DGKVR---VAKATG---EVI--MGHKVNPIGLRLG--VN-RTWDSRWYA------G-Q D--YARLLHEDLKLRAFL--RRKLS-----GAGVSRVVIERPA-K-KPRVTIYAARPGVVIGKKGQDIDALRKELSRMVA LNIVEIRK---PEIDATLVAENIAQQLERRVAFRRAMKRAIQSAMRL-GAQGIRITCGGRLGGAEIARAEKYREGRVPL- -HTLRADIDYGTATAKTTYGTCGVKVWIFMSLSDPLGDMLTRIRNAQRARHAVCVA-PASKLRASVLEALKREGYIRGFA AEE----L-R-K----GVAQLRIELKYV----EG-------Q---PVIKEIHRVSKPGRRVYSKIKELPRVYAGLGVSIL STPRGVLSDVEARAANVGGEVLCRVFMDNQNIRIRLKAYDHRVLDNSTKEIVNTAKRTGARVRGPIPLPTHIERFTVNRS PHVDKKSR-EQFEIRTHRRLLDIVEPTPQTVDALMKLDLAAGVDVEIKLRRVLTGRVTSDKMDKTVTVLLDRRIMHPLYK KFIRRSKKYAAHDEE--NVCQTGDLVRIEECAPISKRKTWSVVSRNASA------------------------------- -MARSV-WKGPFVDG-YLFGKAEASRA---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGHKFLPVQVTE-NMVGH KFGEFSPTRTYTGHG------S---DK----KSK------RG >ALPHA_Granulobacter_bethesdensis_CGDNIH1 Concatenation of 2 sequences M------------------------------------------------------------------------------- ----DFK-R--RK-ADVPATVERLEYDPNRTAFIALIKYQ-DGELSYILAPQRLKAGDVVVSGA-R-AD-IKPGNAMPLG AIPVGTIIHNIEMKPGAGGKIARSAGTYAQLVGK--DAGYAQIKLMSGELRVVRAECYATVGAVSNPDNSNIHIGKAGRS -RWL-----GRR-P-HNRGVVMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGYKTR-TNKRTDS---LIIRRR --------------------------------MRT---G-LIARKLGMTRLFK-EDGT---------HVPVTVLHLDQVQ VVDTR----TKE----R--DGY--TAVQLGF-------GQ--AVSK----------ANKGHFR----------------- ---VK-VEPKKKLVEFRV--------AEDAIL-----EP---GA-TLSA--E-H-FLVGQKVDVTGTSKGKGFAGAMKRW NFAG-LEASHGVSISHRS-HGSTGNR-QDPG-KTFKNKKMAGHLGDERVTTQNVEVAHVDAARG---------------- ----------LLMIRGS-IPGAKGGYVLVR--MQIEIKT-LDNGSA-GTAELPDEIF----AA-TP-RADIMARVVHWQL ACRRAGTHKVKGMGE--------VS-GTTKKPY---------RQKGTGNAR--------QGS---LR-AP----QF---- RTGGAVHGPV-V-RDHGYDLPKKVRRLGLISALSQKQAEG----------------K-LVVIDTA---AGM--------- --EKTRLIV--DGASD--E---GFARASRSLLAVD-V---------------LPTIGANVYDILNHDV----LAITVAGV EALKPRMQQRYNDVV----REALLKEFGYNNRMRVPRLQKIVINMGVG-EAAADQKKLDSAVADLTLIAGQKPVKTVAKK AIAGFKIRKGLPIGAKVTLRKARMYEFLDRLVTIALPRVRDFRGITG-KGFDGRGNFAMGLKEQIVFPEIV-----YDKV DAVRGMDIVFVTT-----------------------AETDAEAKALLKAFDLPF-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MIHPETNLEVADNSGARRVQCIKVLG-SKRK T--ASVGDVIVVSVKEAIPR-G-------KVKKGDVHQAVIVRTSFPVRRADGSAIRFDRNAAVLIN-KQQE-PIGTRIF GPVVRELR-GRKFMKIISLAPEVLMK-L--NELRDNHGA-RPKSKRLG-RGIGSGK-GKTSGKGVKGQKAREGVS----- -LNGF-E-GGQLPIYRRLPK-RG--FVNLNIGTLITEDALRAA-GLVRVR---------LLA--RGE-I-T-R-A-VKI- TVAGASAAARAAVEQAGGSI-K---AHK--GRI---HGNA-KGGTTLNFG----------TFGLKAL--EPERITARQIE AARRAITRAM------KRAGRVWIRIFPDLPVSTKPAEVRMGSGK---------GSPEYWVARVHP-GRVMFEI--DG-- VAPELAREALALGAAKLPIKTKF-ISIDLQERRKQRLRFQL--RAKANGRPRLSVFRSGRHIYAQVIDD---A--AGRTL AAASSL-EKPL-REQL----RTG-ADREAASAVGKLIAER--AQAAG-VSAVVFDRGSYLYH--GRVKALAEAAREGGLA F-------------------------------------------------------------ENE-AQAIVSNLRVSPRK LNLVAQLIRNRKASDAVATLTFS---------------------------------KRRIAQAVKKALESAIAN----A- ENNH-QLDVDRLVVSRAEVGRSIVMRRFHARGRGRAARVEKWFSHLKIVVAEAAKIRKGDQVVVISGE------DK-GKR GEVLRVIPREN--RAV--VRGVAVAKRHLK----PR--GM-GQP-GGIQEQEAPVAISNLM-LVDPKS-------DK--P --TRVGFRI---LD--------NGKVR---VAKVTG---QVI--MGHKVNPIGLRLG--IN-RTWDSRWYA------G-G D--YSRLLHDDLKLRGHL--RKKLS-----GAGVSRVVIERPA-K-KPRVTIYAARPGVVIGKKGQDIEALRKGLTGMVA LNIVEIRK---PEIDATLVAENIAQQLERRVAFRRAMKRAVQSAMRL-GAQGIRINCSGRLGGAEIARIEWYREGRVPL- -HTLRADIDYGVATAKTTYGTCGVKVWIFMQLSDPLGDLLTRIRNAQRSRHATCVS-PASKLRANVLEALKREGYIRGYT SEE--LRP--------GISQLRVELKYN----DG-------E---PVIKEITRVSKPGRRVYSKIKELPRVYAGLGVSIL STPRGVLSDNEARAANVGGEVLCRVFMDNQNIRIRLKAYDHRVLDNSTKEIVNTAKRTGARVRGPIPLPTHIERFTVNRS PHVDKKSR-EQFEIRTHRRLLDIVEPTPQTVDALMKLDLAAGVDVEIKLRRVLTGRVTSDKMDKTVTVLVDRRIIHPLYK KFIRKSKKYAAHDEA--NECREGDIVRIVECPPISKRKTWEVVWRNAAA------------------------------- -MARSV-WKGPFVDG-YLLNKADAARA---SGRNE----IIKIWSRRSTILPQFVGLTFGVYNGHKFLPVQVTE-NMVGH KFGEFSPTRTFPGHA------A---DK----KAK------RG >ALPHA_Hyphomonas_neptunium_ATCC_15444 Concatenation of 2 sequences MALKTFNPTSPGRRQLVLVDRSA-LHKG------------KP-VKALTQGLSSKGGRNNQGRITVRH-QGGGVKRL---- YRQVDFK-R--TR-WDIPATVERLEYDPNRTAFIALIKYQ-DGELSYIIAPQRLEVGDTVITSA-T-AD-IKPGNTLPLK SIPVGTIIHNIELKPQKGAQMVRSAGTYAQLVGR--DSGYAQIKLASGELRMVLDSCLATIGAVSNPDKMNEVSSKAGRN -RHL-----GKR-P-TVRGVVMNPVDHPHGGGEGKS----SGGRHPVSP---WGKKTRGPKTR-NNKV-TD-R-LIIRRR --------------------------------ART---G-VLARKVGMTRIFA-ADGR---------HVPVTVLSLDGCQ VVGVR----SEEERSVTTKKGY--KAVIMGS-------GD--KTTK----------ALRGQFK----------------- ---AG-VAPKAKLKEFRV---------SGDLP-----EV---GS-TVQA--D-H-FAEGQLVDVSAMSIGKGFAGAMKRW NFSG-LRASHGVSISHRA-HGSTGMN-QDPG-RVFKNKKMAGHLGDERVTTQNLVVVRTDVERG---------------- ----------LILVKGS-VPGHDGTFVEVR--MELAVKT-LAGDAA-GNIDLDDAIF----GIDEI-RGDILQRTVRWQL ARRQAGTHKAKSRSE--------VN-RTTKKSI---------KQKGSGGAR--------HGS---RN-AP----IF---- VGGGIAHGPR-V-RSHAHDLPKKIRKMALAHALSSKAKDS----------------S-IMVIDTC----ELD-S------ --PKTKLII--SGTEN--E---NFARAARNIPNID-V---------------LPVAGLNVYDILRRRT----LVITKEAA EGIKPRLKRKYREEI----RTKLQEQFNYSNPMKVPKLDKVVINMGVG-EAVNDSKKIKAALAELERIAGQKPVATKARK SIAGFKVREGMLIGAKVTLRRDQMYEFLDRLTTIALPRVKDFRGLNG-KSFDGQGNYAMGIKEHIVFPEIN-----YDEV EEVRGMDIIVCTT-----------------------AETTEEAKALLAECGFPFMSRIG-K--LAIPVPAGATVT-V--- -A-G--Q-TIKVKGPKGELELVL--PE-V--ITPKFDN-NE--LSV----N-P--RADQDAR-TQWGTARARAANMVEGV TKGYSKTLELVGVGY--RAQMQG-VD--LKLA--LGYSHDVIYKA-P-Q-GIKIEAP--K-PTEIIISG-ADKQAVGQVA AEIKKFR------PPEPY---KGKGIRLQGEYVRRKEGK----------MIQMQSHLRVADNSGARRVMCIKVLG-AGRR Y--ASVGDIIVVSIKEAIPT-G-------RVKKGDVRKAVVVRVAKDINRADGSTIRFDSNAAVLIN-NNGE-PIGTRVF GPVPRELR-AKNQVKIANMAPEVLMK-L--NELSPADGS-TKKRMRVG-RGVGSGK-GKTAGRGVKGQNARSGVA-V--- --NGF-E-GGQMPIYMRLPK-RG--FTSVNLGRIVTEESLVAA-GVVRIR---------LLA--KGD-A-P-Q-K-LTI- TVTGASKAAVEAVEKAGGSV-K---AFK--GQI---NGQS-KGGFTLSFG----------QFGLKAL--EPERVTARQIE ATRRAITREM------KRQGKVWIRVFPDVPVTAKPIEVRMGKGK---------GGVDRWVARVAP-GRILFEI--DG-- VPEDIARQALALGAAKLPIKTKV-VSREKLQRRAQRVRTKL--RRVAEGRPRLSVSRSHKNISVQIIDD---E--KGITL ASASTL-EKEV-IASA----KSS-GNVEAAALVGKAIAER--AKKAG-VEDVVFDRGGYMFH--GRVKALADAAREGGLK F-------------------------------------------------------------AHE-SRAVLRMYRSSPQK LNLLAQQIRGMPIQRALNEMKFS---------------------------------PKRPAKDVYKLLQSAVAN----A- ENNH-GLDIDSLVVAEAHVGKNLVMKRIRARARGRAARIVKPFSQLTIVLRDAAKIKKGDTVIMIAGK------DK-GTK GEVLKVIPDES--RVV--VRGVNMVKRHQK----PS--QT-DP--GGLKSFEAPVHVSNVA-IADPRD-------GK--A --VRVGFKI---DQ--------HGKTR---FAKRSG---ESI--MGQKVNPIGLRLG--IN-RTADSRWYA------DSA D--FGRLLHEDISIRKAI--REKLK-----QAGISKIIIERPH-K-KCLITIHTARPGLVIGKKGGDIEVLRKELAKMVR VNLVEIRK---PEIDATLIADDIARQLERRASFRRAMKRSIQSAMRL-GAEGVKVVVSGRLGGAEIARTEKYAEGSVPL- -HTLRADIDYGTAEATTTYGIIGVKVWVYMNISDPLGDMLTRIRNAQMRGMSKTTS-PASKLRARVLDVLTDEGYIRGYA EIE----KSGHK-------TLEIELKYY----EG-------Q---PVISEIKRVSKPGRRVYSSVSDIPLVRNGLGISIL STSQGVMSDNAARAKNVGGEVLCRVFMERQNIRIRLKAFDHRALDMSAKEIVNTAKRTGAEVRGPVPLPTRIERFTVNRS PHIDKKSR-EQFEIRTHTRILDIVDPTPQTVDALMKLDLSSGVGIEIKLKRIMKGVVVSAKQDKTAIVRVERTFTHPMLK KIVRKTNKYHAHDEN--NVAVEGQTIAIRECAPKSKLKRWEVVA--EEG------------------------------- -MSRSV-WKGPFVDG-YLLKKAEEARS---SEKRA----VIKTWSRRSTILPQFVGLNFQVHNGNKFIPVTVTD-EMVGH KLGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Jannaschia_sp_CCS1 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKSLTEGLTKKGGRNNTGRITARR-RGGGAKRL---- YRIVDFK-R--TK-FDVSATVERIEYDPNRTAFIALVRYE-DGEQNYILAPQRLGVGDKVVASK-K-AD-IKPGNAMPFS GLPIGTIVHNIELKPGKGGQIARAAGTYAQFVGR--DGGYAQIRLSSGELRLVRQECMATVGAVSNPDNSNQNLGKAGRV -RHM-----GKR-P-SVRGVAMNPIDHPHGGGEGRT----SGGRTPVTP---WGKDTKGRRTR-DKNKASQ-K-LIIRSR --------------------------------LRS---G-VIAKKVGMTRLFM-EDGK---------QIPVTVLQLDKLQ VVAKK----TSD----S--DGY--SAVQLGA-------GT--ATSA----------PMRGVFK----------------- ---AS-VEPKRKLVEFRV--------DADNLI-----EV---GE-EIIA--D-H-YFEGQFVDVTGTSIGKGFQGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-RVFKGKKMAGHMGAARVTTQNLQIVRTDTDRG---------------- ----------LIMIKGA-VPGSKGGWVTVK--MKVDVIK-LDGKKA-GSVDLDEALF----GL-EP-RADILHRVVRWQR NNAQAGTHKVKTRRE--------VS-YSTKKIY---------RQKGTGGAR--------HGA---RS-AP----IF---- RGGGVYKGPT-P-RSHGHELTKKFRKLGLRHALSAKAAEG----------------R-LVVIESI----AMD-E------ --AKTSLII--DGSDD--A---NFAQAARNIEGLD-V---------------LPTMGANVYDILKRDT----LVITKAGV EALEPRLKAAFSETI----KAAMKEEFGYKNDMQIPRLEKIVLNIGSGAESVRDTKKAKSAQEDLTAIAGQHAVVTKAKK SIAGFRLREEHPVGAKVTLRGDRMYDFLDRLTTIAMPRIRDFRGVKP--SFDGRGNFAMGMKEHIVFPEIN-----FDKI DVAWGMDIIIVTT-----------------------ANTDAEAKSLLAHFNMPFMSRIG-K--RPVELPGGVEAS-V--- -S-G--Q-TVEVKGPKGTRSFKA--TD-D--VTVSVDG-NV--ISV----E-P--RGKKRAR-QQWGMSRTMVQNLVTGV TDGFKKELEITGVGY--RAQMQG-NV--LKLS--LGYSHDVDFTV-P-E-GVTVTCP--K-NTEVIIEG-NDQQLVGQVA ANIREWR------APEPY---KGKGIRYKGEYIFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SKRK Y--ASVGDVIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILN-NNNE-PMGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--HELSDNPGA-TKKRKRVG-RGPGSGT-GKMGGRGIKGQKSRSGVA----- -INAY-E-GGQMPLYQRLPK-RG--FNKVNLGLIITEDALVAS-GLVRVR---------VLA--KGD-V-S-G-K-LNI- TVTGASKAAIDAVSAAGGAL-K---MQK--GRI---RGEA-KGGSDLTFG----------TYGLKAL--QPERVTARQIE AARRAMTRHM------KRQGRVWIRIFPDTPVTSKPVEVRMGKGK---------GSVDFWACKVKP-GRVMFEI--DG-- VSEPIAREALRLAAMKLPVKTRT-VKRELFQKRRLRNRNKM--RKMANGRARLSVHRSNKNISVQLIDD---L--NGVTL ASASSL-EPSL-------GVVGK-NNVEASAKIGEAIAER--AKKAG-VEECYFDRGGFLFH--GRVKALADAAREGGLK F-------------------------------------------------------------DNE-AMAKLRMLKTSPQK LNLVAGLIRGQKVEKALTDLTFS---------------------------------KKRIAVDVKKCLQSAIAN----A- ENNH-GLDVDELIVAEAWVGKNLVMKRGRPRARGRFGKILKPFSELTITVRQAAKLKKGDKVVVLTGK------DK-GKQ GEISSVNPSAG--KAI--VDGVNIAIRHTK--------QSQSNQ-GGRIPQPMPIQLSNLA-LLDAN--------GK--A --TRVGFKI----E--------DGKVR---VAKTTG---DVI--MGHKVNPIGMRLQ--VN-RTWDSRWYA------DTK D--YGDLLLEDIKIRDYI--KKPAG-----DAGISKIIIERPH-K-KCRVTIHSARPGVIIGKKGADIEGLRKKLAEILH LNIVEIRK---PELDARLVAESIAQQLERRVSFRRAMKRAVQNAMRM-GSLGIRVNVAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYAHAEAETAYGIIGIKTWIF--MNDPISDMLTRIRNSQMRGKSTVET-PASKARARVLDVLADEGYIRGYE AKT--GKD--------GHPAFEISLKYY----EG-------T---PVIRELKRVSKPGRRVYMSVGDIPQVRQGLGVSIV STSKGVMSDANARSQNVGGEVLCTIFAVSQNIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHVDKKSR-DQWEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKVKRILTGTVTSDANEQTVTVSVERRFKHPVMQ KTIRKSKKYRAHDPQ--NSFKTGDQVRIQECAPVSKSKRWEVI-VG---------------------------------- -MSRSV-WKGPFVDS-YVLKKAEKSKE---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGRKHIPVNVTE-DMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Magnetospirillum_magneticum_AMB-1 Concatenation of 2 sequences MALKTFKPTTPGRRQLVLVDRSE-LWKG------------KP-EKSLTEGLRSKGGRNNTGRVTVRW-RGGGHKRR---- YRIIDFK-R--NK-FDVAATVERLEYDPNRTAFIALVSYA-DGEKAYIIAPQRLAVGDQVIASE-K-AD-IKPGNAMPLK NIPVGTIVHNVELKVGKGGQLARSAGTYVQLVGK--DQGYAQLRLASGELRMVRGECMATIGAVSNPDQQNVSLGKAGRA -VWM-----GRR-P-SVRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-SNKK-TD-R-LIMRRR --------------------------------MRS---G-LIAQKVGMTRIFT-EDGT---------HVPVTVLKVDTCQ VVSTR----SVE----K--DGY--VAVQLGA-------GT--AVSK----------PARANFK----------------- ---AK-VEPKKKLVEFRV--------APENLL-----EV---GT-ELSA--A-H-FIPGQYVDVTGTTIGKGFAGGMKRW NFRG-LEATHGVSVSHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGDEQVTTQNLTVVSTDADRG---------------- ----------LILVKGS-VPGHEGSWVLVR--MKTNVIS-LDNQTV-GEIELADEIF----GV-PV-RGDILFRAVNWQL AKRQSGNHKTKTISE--------IS-GTTKKPF---------AQKGGGRAR--------QGS---LR-SA----QF---- RGGSTIFGPV-V-RSHAHDLPKKVRKLALKTALSAKVADG----------------K-LIVVDAA----SAG-S------ --PKTKLFI--DAAVD--G---NFALASRNIPYVD-V---------------LPTQGANVYDILRRDT----LVLTKDAV AALEARLRKHYDTVV----KPALQKEFNYANPMQVPKLQKIVINMGVG-EAAQDSKKIESALAELTLISGQKPVSTKAKM SIAQFKLREGQVVGCKVTLRAERMYEFLDRLINIALPRVRDFRGVPG-KSFDGRGNYSLGLKEQIVFPEID-----YDKV ETIRGMDIIFVTT-----------------------AKSNEEAKALLKGFDMPFMSRVG-K--YPVSVPSGVTVQ-I--- -T-G--P-EVTVKGKLGESKLTL--RD-N--VEVTLDG-NL--IWV----K-P--KNEKHAR-MMWGTTRAHLNNMVKGV SDGFTVNLEINGVGY--RAAVEG-KS--LKLQ--LGYSHDIEYPI-P-D-DVTMKCE--K-PTAISISG-RDKRQVGQIA AEIRAFR------GPEPY---KGKGIKYETETILRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SHRT I--ATVGDVIVVSIKEAIPR-G-------RVKKGDVHRAVIVRTAKEIRRADGSAIRFDTNAAVLIN-KQGE-PIGTRIF GPVTRELR-GKKFMKIISLAPEVLMK-L--NELRDNEGA-RYQSKRLG-RGIGSGK-GKTSGKGVKGQTSRTGVA-I--- --NGF-E-GGQMPIYRRLPK-RG--FHNINLGRLITAEILSAA-GLIGVR---------LLG--HGE-I-K-A-K-VSI- EVTGASAAAIAAVEKAGGSV-K---AHK--GRI---KGVT-KGGSALNFG----------AYGLKAL--EPERITARQIE AARRALTRHM------KRQGRVWIRIFPDLPVSSKPAEVRMGSGK---------GAPEFWTARVAP-GRILFEV--DG-- VAEEIARHGFALAAAKLPIKTKF-IPKNLFERRKRRARQSI--KKKGNGRIRLSVFRSGKNIYVQVIDD---L--NGVTL AAASTL-DKEL-KGNL----KTG-ADKEAAAAVGKLIAER--AKAAG-ITEVVFDRGGYIYH--GRVKALADAAREGGLS F-------------------------------------------------------------DTE-AKAFLASIRTSPRK LNLVAESIRGLKADVALNALTFS---------------------------------KRRIAVEVRKVLQSAIAN----A- ENNH-QLDVDRLYVAEAFVGKAMVMKRWKARARGRVGRIEKPFSNLTVIVRESMNVKKGDRVVVLAGK------DK-GKK GEVIAAMPSEQ--RVI--VQGVNLVKRHTR----PS--AT--SQ-GGIVEKEASIHVSNVA-HEDPKD-------GK--A --TRIGHKI---LE--------DGKVR---VARRSG---EVI--MGQKVNPIGLRVG--IN-RTWDSRWFA------D-E T--YAKLLHQDLKLRKYL--REKLA-----QAGVSRVVIERPA-K-KARITIHTARPGVVIGKKGADIEVLRKELSKMVH LNIVEIRK---PELDAQLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAQGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYGVGTAHTTYGSCGVKVWVFMSMTDPLGDLLTRIRNGQRANKSTVVS-PASSLRANVLEVLKREGYIRGYA RSE--LRP--------GVAQLSIELKYH----EG-------Q---PVIREISRVSTPGRRVYSKIADLRRVANGLGITIL STPRGVMSDTEARTQNVGGEVLCEVFMESQNIRIRLKAFDHRVLDQSTREIVNTAKRTGAQVRGPIPLPSRIEKFTVNRS PHIDKKSR-EQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVSDKMEKTVVVSVERRVMHPIYK KFIRRSKKYHAHDEN--NVFKTGETIRIRECAPISKTKCWEVIV--EPQ------------------------------- -MARSV-WKGPFLDG-YMLGKADKARA---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGQKFIPVLVTE-NMIGH KFGEFSPTRTFYGHA---------VDK----KAK------RK >ALPHA_Maricaulis_maris_MCS10 Concatenation of 2 sequences MALKTFKPTSPGRRALVLVDRSA-LHKG------------RP-EKTLVEGLTKKGGRNNMGRITARR-RGGGAKRL---- YRLVDFK-R--RK-WDMPATVERLEYDPNRTAFIALIKYE-DGEKAYILAPQRLSEGDTVIASA-K-CD-VKPGNAMPLK AVPVGTILHNVEMKPEKGGQIARSAGAYVQLVGR--DAGYAQIRLASGELRMVSDKCMATVGAVSNPDHLNINLGKAGRN -RHL-----GKR-P-SVRGVVMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGAKTR-KNKS-TD-K-FIIRSR --------------------------------RRT---G-VVARKLGMTRIFA-EDGS---------HVPCTVLHMDNVQ VVSHK----TAD----R--DGY--VALQLGA-------GE--ATPK----------AMRGHFK----------------- ---AK-VAPKRKLVEFRV--------AEDALI-----EV---GS-ELTA--D-H-FVPGQKVDVAGISIGKGFAGAMKRH GFGG-LRATHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHMGAVRVTTQNIEVVRVDVERG---------------- ----------IVLVKGA-VPGSAGGWVELR--MKIEVKT-LAAKDA-GAIDLDDAVF----GIEEV-RSDLLQRVVKWQL AARQQGTHKTLGRSE--------IN-RTKKRFG---------RQKGGGTAR--------HGA---RS-AP----QF---- VGGGKAHGPR-V-RSHAHELPKKVRALGLRHALSAKLGAK----------------S-LVIIDDA----ALD-A------ --PQTKLVI--SGAEN--E---NFAKAARNLPCID-V---------------LPAQGLNVYDVLRRDT----LVLTKAAV EQIHPRLRAKYTETI----RAAMKEKFGYANDMMIPRLDKIVINMGVG-EASQDSKKIKGALEDLEAITGQKPVKTVAKK SIAGFKLREEQVIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNG-KSFDGRGNYAMGMKEHIVFPEID-----YDKV EKIRGMDIVVCTT-----------------------AGNDEEAKALLAEFDFPFMSRIG-K--LPVAIPGGVTAT-L--- -S-K--T-ALTVKGPKGELSMTF--VD-E--VSAEQGE-DG--IVI----S-P--RDEKKAR-AMWGMQRALVANLVQGV TAGYEKNLELVGVGY--RAQMQG-TS--LKLS--LGLSHDVVYDA-P-E-GITIAVG--K-PTEVKITG-ADKQRVGQVA AEIRRFR------PPEPY---KGKGIKYVGEYIRRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-AKRR Y--AHVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRVAKDIQRKDGSVIRFDGNAAVIIN-NNNE-PLGTRIF GPVPRELR-AKNHMKIVSLAPEVLMR-L--NELRDNDGA-TKIRTRVG-RGIGSGK-GKTGGRGVKGQKSRSGVA----- -IKGF-E-GGQMPLHMRLPK-RG--FNKVNLGRLIDADVLIAA-GLVRVR---------LLA--KGE-L-K-S-K-VEI- TLAGASKAAIAAVEKAGGKV-K---AHK--GRI---KGAA-KGGFTLNFG----------SYGLKAL--QPERVTARQIE ATRRAITRHM------KRAGRVWIRIFPDVPVSKKPTEVRMGKGK---------GSPEFWACKVKP-GRIMFEI--DG-- VPENVAREALELGAAKLPVKTKI-VQREKSVRRAQRNRIRL--RKFANGRPRLSVYRSSKNIYAQIIDD---A--SGKTV VAASSL-EEAA-QKEH----GKG-WDTKAAELVGKLIAER--AVKEG-VKDVVFDRGGYIFH--GRVKALAEAAREGGLN F-------------------------------------------------------------DNE-ARAKLRMIRTSPQK LNLVAALIRGKKVERALADLEFS---------------------------------RKRISKEVKKTLESAIAN----A- ENNH-GLDIDSLVVSEAFVGKNLVMKRFRARARGRGAKILKPFSELTIVVREAAKIKKGDKVVILAGR------DK-GKT GEVTKVLPTED--RVV--VAGVNVVKRHTR----AT--QT--EQ-GGIIEKEASIHVSNVA-VADPKT-------GE--A --TRVGFKT----E--------DGKVR---VAKSSG---EVI--MGQKVNPIGLRLG--VN-RTWESRWYA------GAG E--YAKLLHEDIKIRKML--KERLK-----NASVSKIVIERPH-K-KCRVTVHTARPGVVIGKKGSDIETLRKELSKMVH LNLVEVRK---PEIDAALVAESIAQQLERRVAFRRAMKRSMQSAMRM-GAKGCKIVCGGRLGGAEIARTEQYNEGSVPL- -HTLRADIDYGTCEAKTAMGIIGIKVWIYMSVNDPLGDMLTRIRNALMRNKRAVNT-PASALRRRVLDVLKSEGYIRDYA EVE--HAS--------GLKEFEIELKYF----EG-------D---SVISEIKRISKPGRRVYSGVKDLPLVQNGLGIAIL STPKGVMSDSTARESNVGGEILCHVSMERQNIRIRLKAFDHRVLDNSTREIVSTAKRTGANVRGPIPLPTRIEKFTVLRS PHIDKKSR-EQFEIRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRILQGVVVSDKGAKTIVVRVERTFLHPLLR KTVRRTKRYHAHDEA--NAYKVGDQVQIQECAPKSKLKRWEVVT---VA------------------------------- -MPRSV-WKGPFVDG-YLLKKAEKSHE---GGRKQ----AIKTWSRRSTIMPQFVGLTFQVHNGNKFVPVLVTE-DMVGH KLGEFSPSRTYYGHA------A---DK----KAK------RR >ALPHA_Mesorhizobium_loti_MAFF303099 Concatenation of 2 sequences MALKKFNPVTPSTRQLVIVDRSG-LYKG------------KP-VKGLTEGLTKSGGRNNYGRITARF-IGGGHKRS---- YRIIDFK-R--RK-FDVVGTVERIEYDPNRTAFIALIKYD-DGELSYIIAPQRLAAGDKIVAGE-A-VD-VKPGNAMPLA SMPVGTIVHNIELKPGKGGQVARSAGGYAQLVGR--DQGMAILRLNSGEQRVVHGSCMATVGAVSNPDHGNINDGKAGRT -VWR-----GKR-P-HNRGVTMNPVDHPHGGGEGRT----SGGRHPVSP---WGKPTKGKKTR-SNKA-TD-K-FILRSR --------------------------------MRS---G-VIAKKVGMTRIYN-DAGE---------HVPVTVLQMENCQ VVAQR----TQE----K--NGY--TAVQLGV-------GL--ATSK----------AMRGHF------------------ ---TASVEPKAKVAEFRV--------SADNMI-----DV---GA-EITV--E-H-FVAGQKVDVTGTTIGKGFQGVIKRH HMGG-GRATHGNSVSHRT-HGSTGQR-QDPG-KVFKGKKMAGHMGDTRVTTQNVEIVSTDADRG---------------- ----------LILIRGA-VPGSKGAWILVR--MDLKITT-LGGKDA-GKVKLSEEIF----GL-DP-REDILQRVVRWQL AKKQQGTHKAKGRAE--------IA-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKNVRALGLKHALSAKAKSA----------------S-IIVIDEL----KLT-E------ --AKTKLVI--GAELD--K---NFKLAATNIPNID-V---------------LPIQGINVYDILRRGT----LVLSKAAV EALEPRLKQVYNETI----RKALQEQFGYDNDMQVPRLDKIVLNMGVG-EATADSKKPSVAAEDLALIAGQKAVVTRARN SIAGFKVRENMPIGAKVTLRKERMYEFLDRLVNIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDVIVCTT-----------------------AKTDDEARALLKAFNFPFMSRIG-K--KPVSLPQGVTAT-V--- -N-G--Q-TVTAKGPKGELKFVV--ND-E--VLVKMEG-SE--IAV----Q-P--RDQKTAR-SKWGMSRTQIVNILHGV KDGFEKKLEITGVGY--RAAMQG-KN--LQLA--LGFSHDVVYET-P-A-GVTIAVP--K-PTEITVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVRYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDKNAAVLVD-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKDGA-THSKKRLG-RGIGSGS-GKTAGRGVKGQKARSGVA----- -INGF-E-GGQMPLYRRLPK-RG--FNNVSLARIVTAEALVAA-GVIRVR---------VLS--DGE-L-K-A-K-LAF- DVAGASKAAIEKIEKAGGSV-K---QFK--GRI---HGTA-KGGTNLDFG----------GFGLKAL--EPNRVTAREIE AARRAITREM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GAVDYWAARVKP-GRIMFEI--DG-- VSEETAREALRLGAAKLSVRTRF-VTKESTQRRAQRVRRQI--RKVAGERPRLSVHRTSKNIYVQVIDD---A--KGHTI AAASTL-EKDL-KGSL----KTG-ADTAAAAAIGKLIAER--ATKAG-VKEVVFDRGPYIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-ARAVLRTIRISPQK LNLVAALIRGKKVATALSDLEFS---------------------------------AKRISGTVKKTLESAIAN----A- ENNH-DLDVDALVVAEAYVGKSIVMKRFHARGRGRASRIEKPFSHLTIVVREMQKIRKGDKVVVLAGK------DK-GRS GEVLSVQPKDD--TAL--VRGVNMIRRHQK--------QSQSQE-GGIITKEAPIQLSNIA-LADPKD-------GK--P --TRVGFIF---QK--------DGKVR---VAKRSG---EVI--MGQKVNPIGLRLG--IN-RTWDSRWFA------NTG E--YGKLLHEDIKIRKYL--EKELK-----QAAISKVVIERPH-K-KCRVTIHAARPGLIIGKKGADIEKLRKKLMEMTH LNIVEVRK---PEIDATLVAQSIAQQLERRIAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYGTAEANTAYGICGVKVWVFMSLSDPLGDMLTRIRNAYGRKKSSVST-PASRLRTRVLDVLKAEGYIRDYS QTD---FD---N----GKSEIEIELKYF----DG-------A---PVVREIARVSKPGRRVYVSAKSIPHVANGLGIAIL STPKGVMADHEAREQNVGGEILCQIFMNGQNIRIRLKAFDHRVLDASTKEIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGTVVSDKNEKTVVVKVERRFTHPVMK KTVRMTKKYKAHDEN--NAHKVGDQVFIQESKPISKDKRWIVVS--SDQ------------------------------- -MTRSI-WKGPFIDG-YLLKKVDKVRE---GGRNE----VIKMWSRRSTILPQFVGFTFGVYNGQKHVPVSVNE-DMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Mesorhizobium_sp_BNC1 Concatenation of 2 sequences MALKNYKPVTPGQRQLVIVDRSG-LHKG------------KP-VKGLTVGLTSKGGRNNYGRITARF-QGGGHKRT---- YRLIDFK-RR--K-FDVSGVIERLEYDPNRTGFIALVRYD-DGELSYILAPQRLAAGDRVISSAQS-VD-VKPGNAMPLA AMPVGTIVHNVELKPGKGGQIARSAGSYAQLVGR--DQGMAILRLNSGEQRLVSGTCMATVGAVSNPDHANVSLGKAGRK -RWL-----GKR-P-HNRGVTMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGKPTKGRKTR-S-NKATD-K-FIMRSR --------------------------------MRS---G-VIAQKIGMTRVYN-ETGE---------HIPVTVLRMENCQ VVAQR----TEE----K--NGY--TAVQLGV-------GL--ATSK----------ALRGHF------------------ ---AASVEPKAKVAEFRV--------SPENLL-----DV---GA-EITA--D-H-FVPGQKVDVTGTSIGKGFQGVMKRH NFGG-GRATHGNSVSHRT-HGSTGQR-QDPG-KVFKGKKMAGHMGDRRVTTQNLEVVSTDTERG---------------- ----------LILVRGA-VPGSKGSWIMVR--MDLKVTT-LAGKDA-GKVEVSDEIF----GL-DP-REDILHRVVRWQL AKRQQGTHKAKGRAE--------IA-RTGAKMY---------RQKGTGRAR--------HSS---AR-AP----QF---- RGGGKAHGPV-P-HSHAHDLPKKVRALGLKHALSAKAKSA----------------N-LIIVDDL----AIK-E------ --AKTKLMI--GAEID--A---GFKRAAANIPNID-V---------------LPIQGINVYDILRRGT----LVLSKAAV EALEPRLKKHYEEAI----RKQLLETFKYENEMQVPRIDKVVINMGVG-EATGDSKKPSVAAEDLALIAGQKAVITRARN SIAGFKVREGMPIGAKVTLRKDRMYEFLDRLVNVALPRVRDFRGLSP-KSFDGHGNFAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARALLKAFNFPFMSRIG-K--KPVPVPQGVTAN-V--- -D-G--Q-VVTAKGPKGELKFVV--ND-D--VLVKLED-GA--IAV----D-P--RNEKMAR-SKWGMSRTQIANILTGV KDGFEKRLEINGVGY--RAAMQG-KN--LQLS--LGFSHDVSYEP-P-T-GITITVP--K-PTEIVVSG-IDKQVVGQVA AEIRKYR------GPEPY---KGKGVKYAGETIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDSNAAVLVD-NKRE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NELRDAEGA-TKARKRVG-RGIGSGS-GKTGGRGVKGQKSRSGVA----- -IKGF-E-GGQMPLYRRLPK-RG--FTNVSLGRIIDGAALLNA-GVIRVR---------VLS--GGE-I-T-A-K-VTL- DVAGASKSAVEKIEKAGGSV-K---QFK--GRI---HGAA-KGGTDLNFG----------AFGLKAL--EPERVTARQIE AARRAITRQM------KRQGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEFWACRVKP-GRIMFEI--DG-- VAEDIAREALRLGAAKLPIKTRF-ISKVSVTRRAGRVRRKL--KAVATERPRLSVYRSSKHIYAQVIDD---V--KGHTL AAASSL-DKDL-REKL----KTG-ADVDAAGVVGKLIAER--AKKAG-IDKVVFDRGPYIYH--GRVKALADAAREGGLE F-------------------------------------------------------------DNE-ARAVLRTIRVSPQK LNLVAALIRGKKVATALADLEFS---------------------------------RKRIADTVKRTLESAIAN----A- ENNH-NLDVDALVVAEAYVGKSIVMKRFHARGRGRANRIEKPFSHLTIVVREMQKIKKGDKVVVLSGR------DK-GRT GEVLKMMPKED--RAL--VRGVNLVRRHQK----QT--PQ-A-E-GGIITKEAPIHVSNLA-LADPKD-------GK--P --TRVGFKI---QE--------DGKVR---VAKRSG---ELI--MGQKVNPIGLRLG--IN-RTWDSRWFA------NTN E--YGQLLHEDLKIRTYI--ENELK-----QAAISKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRRKITQMTH LNIVEVRK---PEIDARLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCTGRLGGAEIARIEWYREGRVPL- -HTLRADIDYGTAEAKTAYGVCGVKVWVFMSVNDPLGDMLTRIRNAIGRKKTTVST-PASRLRARVLDVMKAEGYIRDYT QVD---YD---N----GKSELEIQLKYL----EG-------A---PVIREIARVSKPGRRVYVSVKSIPHVANGLGIAIL STPKGVMADHEAREKNVGGEFLCQIFMNGQNIRIRLKAFDHRVLDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS THIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGTVVSDKNDKTVVVRVERRFAHPLLK KTVRRSKRYKAHDEN--NMCKVGDVVLIQETRPISKDKCWVVVN--NQA------------------------------- -MSRSV-WKGPFVDG-YLLKKADKSRE---SGRKE----VIKTWSRRSTILPQFVGLTFGVYNGQKHIPVSVSE-EMVGH KLGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Methylobacterium_chloromethanicum_CM4 Concatenation of 2 sequences MALKTFKPVTPSLRQLVLVDRRE-LYKG------------KP-VKALTEGKSSSGGRNNLGRITVRF-RGGGHKRV---- LRNVDFK-RR-EN-LNVPATVERIEYDPNRTAFIALITFP-DGKQSYILAPQRLSPGDKVIAGE-S-VD-VKPGNAAPIG SMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGR--DQGYVTLRLNSGEQRLVHGQCFATVGAVSNPDHMNISLGKAGRN -RWL-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRN-PVTP---WGVPTKGKKTR-S-NKRTD-T-FILSSR --------------------------------MRS---G-VIARKVGMTRVFT-DAGE---------HVPVTVLQIDQCQ VVAHR----TTE----K--DGY--VALQVGV-------GK--AVSQ----------AERGRF------------------ ---VAKVEPKKKLAEFRV--------SEDALI-----PV---GA-EITA--D-H-FIPGQFVDVTGTSTGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHLGVERVTTQNLKVVRTDPERG---------------- ----------LILVEGA-VPGVAGGWIQVR--MKLDITT-LDGGSA-GSVELNEAIY----GL-EP-RADILQRMVRYQL AKRRAGTHAVKNRSD--------VD-RTSKKLY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGGRAFGPV-V-RDHSHDLPKKVRALALKHALSAKAKAS----------------T-LIVVDDI----KVD-N------ --HKTKLII--GGSED--E---NFGRAARAIPKID-V---------------LPVQGINVYDILRRDT----LVLTRAAV DALEPRLRKHYDEVV----RQKLIEQFGYANPMQVPQIEKIVINMGVG-ESTADSKKATVAAGDLALIAGQKPVITRARK AIATFKVREGMPIGCKVTLRKARMYEFMDRLVTIALPRVRDFRGLNP-RSFDGRGNYAMGLKEHLVFPEIS-----YDKA EQTWGMDIVVQTS-----------------------ATTDEEAKALLAHFKFPFMSRVG-K--KPVPVPSGVTAT-V--- -T-G--Q-TVKVKGSKGELQFVV--PS-Q--VVVEFKD-GA--VSV----Q-P--KDQKQAR-SLWGTSRAQVANLVEGV SKGFEKKLEITGVGY--RAAMAG-KA--LKLS--LGYSHDIEYEI-P-A-GITIVTP--K-PTEIVVSG-IDRQRVGQVA AEIREYR------GPEPY---KGKGVKYAGEFIFRKEGK-------------MQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDVKRADGSVIRFDKNAAVLIN-NQKE-PVGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NEIRDNEGA-TKARMRVG-RGIGSGK-GKTGGRGVKGQKARSGVS----- -IKGF-E-GGQMPLHRRLPK-RG--FNNVNLGRVVTVEALVKA-GIISVK---------LLG--VGE-L-T-S-K-LSF- EVTRASKSAIEAVEKAGGSV-K---QFK--GRI---SGAA-KGGFELNFG----------QFGLKCL--EPERITARQIE AARRAITREM------KRQGRVWIRVFPDLPVTAKPTEVRMGSGK---------GAPEYWAARVHP-GRIMFEV--DG-- VAEDIAREALRLGAAKLPVRTRV-IKNEALLRRKARVRRAL--RAAANGRPRLSVFRSSKQIYVQVIDD---A--AGRTL AAASSL-DKDL-KSSL----KTG-ADKAAAEAVGKLVAER--AKAAG-VTKVVFDRSGYIFH--GRVKALADAAREGGLD F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAALIRGKKVDTALADLEFS---------------------------------RKRIARDVKKCLESAIAN----A- ENNH-DLDVDDLVVSQAFVGKALVLKRFHARARGRGARILKPFANLTIVVREAAKIKKGDTVVVLTGR------DA-GRS GEVIQVMPKED--KAF--VRGVNLVKKHQR--------QTQNQE-GGIISKEAAIQLSNIA-VADAN--------GK--P --TRVGFRI---LD--------DGKVR---FAKTTG---DQI--MGQKINPIGLRLG--IN-RTWDSRWFA------EKG E--YAKLMHEDVAIRAAL--MKQLK-----QAAVSKIVIERPH-R-KCRVTIHSGRPGVVIGKKGADIEKLRKLVGTMVT INIVEVRK---PEIDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGIKVWVF-MVNDPVGDMLTRIRNGQSRRRNVVQT-PGSRLRASVLDVLKSEGYIRDYA VQD--LGN--------GRTEFQIELKYY----DG-------R---PVIREIKRVSKPGRRVYSSVGELPRVADGLGVTII STPQGVMADHVARERNVGGEVLCKVFMNGQNIRIRLKAFDHRILDASTKEIVSTARRTGAQIRGPIPLPTHIEKFTVNRS PHIDKKSR-EQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVVSDKTDKTIVVKVERRFTHPVMK KTVRRSKNYHAHDEA--NAAKIGQTVFIEESRPYSKTKTWKLVEDQEAA------------------------------- -MARSL-WKGPFVDG-YLLKKADAARG---GSRNE----VVKIWSRRSTILPQFVGITFGVHNGHKHIPVYVTE-EMVGH KFGEFSPTRTFPGHA------A---DK----KAK------RR >ALPHA_Methylobacterium_extorquens_PA1 Concatenation of 2 sequences MALKTFKPVTPSLRQLVLVDRRE-LYKG------------KP-VKALTEGKSSSGGRNNLGRITVRF-RGGGHKRV---- LRNVDFK-RREN--LNVPATVERIEYDPNRTAFIALITFP-DGKQSYILAPQRLSPGDKVIAGE-S-VD-VKPGNAAPIG SMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGR--DQGYVTLRLNSGEQRLVHGQCFATVGAVSNPDHMNISLGKAGRN -RWL-----GKR-P-HVRGVAMNPVDHPHGGGEGRT----SGGRNPVTP---WGVPTKGKKTR-SNKR-TD-T-FILSSR --------------------------------MRS---G-VIARKVGMTRVFT-DAGE---------HVPVTVLQIDQCQ VVAHR----TTE----K--DGY--VALQVGV-------GK--AVSQ----------AERGRFV----------------- ---AK-VEPKKKLAEFRV--------SEDALI-----PV---GA-EITA--D-H-FIPGQFVDVTGTSTGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHLGVERVTTQNLKVVRTDPERG---------------- ----------LILVEGA-VPGVAGGWIQVR--MKLDITT-LDGGSA-GSVELNEAIY----GL-EP-RADILQRMVRYQL AKRRAGTHAVKNRSD--------VD-RTSKKLY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGGRAFGPV-V-RDHSHDLPKKVRALALKHALSAKAKAS----------------T-LIVVDDI----KVD-N------ --HKTKLII--GGSED--E---NFGRAARAIPKID-V---------------LPVQGINVYDILRRDT----LVLTRAAV DALEPRLRKHYDEVV----RQKLIEQFGYANPMQVPQIEKIVINMGVG-ESTADSKKATVAAGDLALIAGQKPVITRARK AIATFKVREGMPIGCKVTLRKARMYEFMDRLVTIALPRVRDFRGLNP-RSFDGRGNYAMGLKEHLVFPEIS-----YDKA EQTWGMDIVVQTS-----------------------ATTDEEAKALLAHFKFPFMSRVG-K--KPVPVPSGVTAT-V--- -T-G--Q-TVKVKGSKGELQFVV--PS-Q--VVVEFKD-GA--VSV----Q-P--KDQKQAR-SLWGTSRAQVANLVEGV SKGFEKKLEITGVGY--RAAMAG-KA--LKLS--LGYSHDIEYEI-P-A-GITIVTP--K-PTEIVVSG-IDRQRVGQVA AEIREYR------GPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDVKRADGSVIRFDKNAAVLIN-NQKE-PVGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NEIRDNEGA-TKARMRVG-RGIGSGK-GKTGGRGVKGQKARSGVS----- -IKGF-E-GGQMPLHRRLPK-RG--FNNVNLGRVVTVEALVKA-GIISVK---------LLG--VGE-L-T-S-K-LSF- EVTRASKSAIEAVEKAGGSV-K---QFK--GRI---SGAA-KGGFELNFG----------QFGLKCL--EPERITARQIE AARRAITREM------KRQGRVWIRVFPDLPVTAKPTEVRMGSGK---------GAPEYWAARVHP-GRIMFEV--DG-- VAEDIAREALRLGAAKLPVRTRV-IKNEALLRRKARVRRAL--RAAANGRPRLSVFRSSKQIYVQVIDD---A--AGRTL AAASSL-DKDL-KSSL----KTG-ADKAAAEAVGKLVAER--AKAAG-VTKVVFDRSGYIFH--GRVKALADAAREGGLD F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAALIRGKKVDTALADLEFS---------------------------------RKRIARDVKKCLESAIAN----A- ENNH-DLDVDDLVVSQAFVGKALVLKRFHARARGRGARILKPFANLTIVVREAAKIKKGDTVVVLTGR------DA-GRS GEVIQVMPKED--KAF--VRGVNLVKKHQR----QT--QN--QE-GGIISKEAAIQLSNIA-VADAN--------GK--P --TRVGFRI---LD--------DGKVR---FAKTTG---DQI--MGQKINPIGLRLG--IN-RTWDSRWFA------EKG E--YAKLMHEDVAIRAAL--MKQLK-----QAAVSKIVIERPH-R-KCRVTIHSGRPGVVIGKKGADIEKLRKLVGTMVT INIVEVRK---PEIDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGIKVWVF-MVNDPVGDMLTRIRNGQSRRRNVVQT-PGSRLRASVLDVLKSEGYIRDYA VQD--LGN--------GRTEFQIELKYY----DG-------R---PVIREIKRVSKPGRRVYSSVGELPRVADGLGVTII STPQGVMADHVARERNVGGEVLCKVFMNGQNIRIRLKAFDHRILDASTKEIVSTARRTGAQIRGPIPLPTHIEKFTVNRS PHIDKKSR-EQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVVSDKTDKTIVVKVERRFTHPVMK KTVRRSKNYHAHDEA--NAAKIGQTVFIEESRPYSKTKTWKLVEDQEAA------------------------------- -MARSL-WKGPFVDG-YLLKKADAARG---GSRNE----VVKIWSRRSTILPQFVGITFGVHNGHKHIPVYVTE-EMVGH KFGEFSPTRTFPGHA------A---DK----KAK------RR >ALPHA_Methylobacterium_nodulans_ORS_2060 Concatenation of 2 sequences MALKTFKPVTPSLRQLVIVDRSE-LYKG------------KP-VKALTEGKISSGGRNNLGRVTVRF-RGGGHKRT---- LRNVDFK-R--REHAGKVGTVERIEYDPNRTAFIALVTYE-GGAQSYILAPQRVKAGDKVVSGD-S-VD-IKPGNAMPIG NMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGR--DQGYVTLRLNSGEQRLVHGQCYATVGAVSNPDHMNISLGKAGRK -RWL-----GRR-P-HNRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGFPTKGKKTR-SNKRTDT---FIVSSR --------------------------------MRS---G-VIAQKVGMTRVFT-DAGE---------HVPVTVLKVDQCQ VVAHR----TVE----K--NGY--VALQVGV-------GK--AVSK----------AERGRF------------------ ---IAKVEPKRKLAEFRV--------SEDALI-----PV---GA-EITA--D-H-FIPGQFVDVTGITTGKGFAGGMKRW NFGG-LRASHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHLGVERVTTQNLRVVRTDPERG---------------- ----------LILVEGA-VPGVAGGWIHVR--MKFEITT-LDGADA-GSVELDEAIF----GL-EP-RADLLQRCVRWQL AKRQAGTHKVKTRSE--------IS-RTTKKMY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGARAFGPV-V-RSHAHDLPKKVRALALRHALSAKAKDA----------------S-LIVVDDV----RLE-D------ --GKTKLII--GGTED--E---NFGRAARNLPSID-V---------------LPVQGINVYDILRRDK----LVLTRAAV DALEPRLKKHYDEVV----RAKMIQEFGYTNPMQVPTIEKITINMGVG-ESTQDSKKASIAAEDLGLIAGQKPVITRARK AIATFKVRENMPIGCKVTLRRQRMYEFMDRLITIALPRVRDFRGLNP-KSFDGRGNYALGLREHLVFPEIN-----YDKA QNAWGMDIVVTTT-----------------------AKTDAEARALLKHFNFPFMSRVG-K--KPVPVPAGVTAT-V--- -D-G--Q-TVKVKGSKGELQFRV--PD-Q--VAVTHEN-GA--ISV----Q-P--RSQKEAR-ALWGLSRAQVANLVEGV TKGFEKKLEINGVGY--RAAVAG-KV--LKLS--LGYSHDIEYEI-P-A-GITITTP--R-PVEIIVAG-IDKQRVGQIA AEIREYR------SPEPY---KGKGVKYADEFIFRKEGK-------------MQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDVRRPDGSVIRFDRNAAVLIN-NQKE-PIGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NEIRDNEGA-TKNRMRVG-RGIGSGK-GKTAGRGVKGQKARTGVA----- -IKGF-E-GGQMPLHRRLPK-RG--FTNVNIGRIVTVEALLAA-GIVSVK---------ILG--VGE-L-S-A-K-LTF- QVARASKSAVAAIEKAGGSV-K---QFK--GRI---HGAA-KGGTDLNFG----------SYGLKAL--EPERVTARQIE AARRAITREM------KRQGRVWIRIFPDVPVTQKPTEVRMGSGK---------GSPEYWAARVHP-GRVMFEI--DG-- VAEDIAREALRLGAAKLPVRTRF-IKIDLLDRRRARVRRAI--RAAANGRPRLSVFRSSKQIYVQVIDD---A--NGRTL AAASSL-DKDL-RARL----KTG-ADKAAAAEVGKLVAER--AKAAG-VTKVIFDRSGYLYH--GRVKALADAAREGGLD F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAQLIRGKKVATALADLQFS---------------------------------QKRIAVEVKKCLESAIAN----A- ENNH-DLDVDDLVVKEAYVGKALVLKRFHARARGRGARILKPFSNLTIVVREAAKVKKGDTVVVLTGR------DK-GRS GEVIQVMPKEN--RAL--VRGVNLVKRHQR--------QTQAQE-GGIISKEAAIDLSNLA-VADPKD-------GK--P --TRVGFRI---LE--------DGKVR---FAKRSG---DLI--MGQKVNPIGLRLG--IN-RTWDSRWYA------NKG E--YARLMHEDVAIRQAL--MKQLK-----QAAVSKIVIERPH-R-KCRVTIHSGRPGVVIGKKGADIEKLRKLVGTMVT INIVEVRK---PEIDATLVADSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGIKVWVF-MITDPVGDMLTRIRNGQQRRRNVVQT-PGSKLRARILDVLKAEGYIRDYA TTD----Y-GNG-----RTEFAIELKYH----DG-------A---PVIRSIERVSKPGRRVYSSVDTLPRVADGLGITIV STPLGVMADHEARERNVGGEVLCKVFMNGQNIRIRLKAFDHRILDSSTREIVSTAKRTGAQVRGPIPLPTRIERFTVNRS PHIDKKSR-EQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVISDKQDKTVVVKVERRFTHPVMK KTVRRSKNYHAHDEN--NVAKVGQTVFIEESRPYSKLKTWKLVEEAVAS------------------------------- -MARSV-WKGPFVDG-YLLKKAEAARG---STRSE----VIKIWSRRSTILPQFVGLTFGVYNGQKHIPVYVSE-EMVGH KFGEFSPTRTFHGHA------A---DK----KAK------RR >ALPHA_Methylobacterium_populi_BJ001 Concatenation of 2 sequences MALKTFKPVTPSLRQLVLVDRRE-LYKG------------KP-VKALTEGKSSSGGRNNLGRITVRF-RGGGHKRV---- LRNVDFK-RR-EN-LNVPATVERIEYDPNRTAFIALITFP-DGKQSYILAPQRLSPGDKVVAGE-S-VD-VKPGNAGPIG SMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGR--DQGYVTLRLNSGEQRLVHGQCFASVGAVSNPDHMNISLGKAGRN -RWL-----GKR-P-HNRGVAMNPVDHPHGGGEGRT----SGGRNPVTP---WGVPTKGKKTR-SNKR-TD-T-FILSSR --------------------------------MRS---G-VIARKVGMTRVFT-DAGE---------HVPVTVLQIDQCQ VVAHR----TTE----K--DGY--VALQVGV-------GK--AVSQ----------AERGRF------------------ ---VAKVEPKKKLAEFRV--------SEDALI-----PV---GA-EITA--D-H-FIPGQFVDVTGTTTGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHLGVERVTTQNLKVVRTDPERG---------------- ----------LILVEGA-VPGVAGGWIQVR--MKLDITT-LDGGSA-GSLELNEAIF----GL-EP-RADILQRMVRYQL AKRRAGTHAVKNRSD--------VD-RTTKKLY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGGRAFGPV-V-RDHSHDLPKKVRALALKHALSSKAKTS----------------T-LIVVDDI----KVD-S------ --HKTKLII--GGSED--E---NFGRAARAIPKID-V---------------LPVQGINVYDILRRDT----LVLTRAAV DALEPRLRKHYDEVV----RQKLIEQFGYKNPMQVPQIEKIVINMGVG-ESTADSKKATVAAGDLALIAGQKPVITRARK AIATFKVREGMPIGCKVTLRKARMYEFMDRLITIALPRVRDFRGLNP-RSFDGRGNYAMGLKEHLVFPEIS-----YDKA EQTWGMDIVVQTS-----------------------ATTDEEAKALLAHFKFPFMSRVG-K--KPVPVPSGVTAT-V--- -T-G--Q-TVKMKGSKGELQFVV--PP-Q--VIVEFKD-GA--VSV----Q-P--KDQKQAR-SLWGTSRAQVANLVEGV SKGFEKKLEITGVGY--RAAMAG-KA--LKLS--LGYSHDIEYEI-P-A-GITIVTP--K-PTEIVVSG-IDRQRVGQVA AEIREYR------GPEPY---KGKGVKYAGEFIFRKEGK-------------MQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDVKRADGSVIRFDKNAAVLIN-NQKE-PVGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NEIRDNEGA-TKNRMRVG-RGIGSGK-GKTGGRGVKGQKARTGVS-I--- --KGF-E-GGQMPLHRRLPK-RG--FNNVNLGRVVTVDALVKA-GIIAVK---------LLG--VGE-L-T-A-K-LSF- EVTRASKSAVEAVEKAGGSV-K---QFK--GRI---SGAA-KGGFELNFG----------QFGLKCL--EPERITARQIE AARRAITREM------KRQGRVWIRVFPDLPVTAKPTEVRMGSGK---------GAPEYWAARVHP-GRIMFEV--DG-- VAEDIAREALRLGAAKLPVRTRV-IKNEALLRRKARVRRAL--KATANGRPRLSVFRSSKQIYVQVIDD---A--VGRTL AAASSL-DKDL-KASL----KTG-ADKAAAEAVGKLVAER--AKAAG-VTKVVFDRSGYIFH--GRVKALADAAREGGLD F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAALIRGKKVDTALADLEFS---------------------------------RKRIARDVKKCLESAIAN----A- ENNH-DLDVDDLVVSQAFVGKALVLKRFHARARGRGARILKPFSNLTIVVREAAKIKKGDTVVVLTGR------DA-GRS GEVIQVLPKDG--KAF--VRGVNLVKKHQK----QT--QN--AE-GGIISKEAAIQLSNLA-FQDVN--------GK--P --TRVGFRI---LE--------DGKVR---FAKTTG---DQI--MGQKINPIGLRLG--IN-RTWDSRWFA------EKG E--YAKLMHEDVAIRAAL--MKQLK-----QAAVSKIVIERPH-R-KCRVTIHSGRPGVVIGKKGADIEKLRKLVGTMVT INIVEVRK---PEVDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGIKVWVF-MVNDPVGDMLTRIRNGQSRRRNVVQT-PGSRLRASVLDVLKSEGYIRDYA VQD--LGN--------GRTEFAIELKYY----DG-------R---PVIREIKRVSKPGRRVYSSVGELPRVADGLGVTII STPQGVMADHEARERNVGGEVLCKVFMNGQNIRIRLKAFDHRILDASTKEIVSTARRTGAQIRGPIPLPTHIEKFTVNRS PHIDKKSR-EQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVVSDKTDKTIVVKVERRFTHPVMK KTVRRSKNYHAHDEA--NTAKVGQTVFIEESRPYSKTKTWKLVEDQEAA------------------------------- -MARSL-WKGPFVDG-YLLKKADAARG---GSRNE----VVKIWSRRSTILPQFVGITFGVHNGHKHIPVYVTE-EMVGH KFGEFSPTRTFPGHA------A---DK----KAK------RR >ALPHA_Methylobacterium_radiotolerans_JCM_2831 Concatenation of 2 sequences MALKTFKPVTPSLRQLVLVDRRE-LYKG------------KP-VKALTEGKSSSGGRNNLGRITVRF-RGGGHKRV---- LRNVDFKRR--DQ-LGVAATVERIEYDPNRTAFIALINFP-DGKQSYILAPQRLQPGDKVVAGE-S-VD-IKPGNAGPVG SMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGR--DQGYVTLRLNSGEQRLVHGQCFASVGAVSNPDHMNISLGKAGRN -RWL-----GKR-P-HNRGVAMNPVDHPHGGGEGRT----SGGRNPVTP---WGVPTKGKKTR-SNKRTDV---FILSSR --------------------------------MRS---G-VIAQKVGMTRVFT-DAGE---------HVPVTVLKIDQCQ VVAHR----TVE----K--NGY--VALQVGV-------GK--AVSA----------AERGRF------------------ ---VAKVEPKKKLAEFRV--------TEDALI-----PV---GA-EITA--D-H-FIPGQFVDVTGTTTGKGFAGGIKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHLGVERVTTQNLRVVRTDPERG---------------- ----------LILVEGA-VPGVAGGWIQIR--MKLDIKT-LDGAGA-GSVELNEEIF----GL-EP-RADLLQRMVRWQL AKRRAGTHAVQNRSD--------VN-RTRKKLY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGGRAFGPV-V-RDHSHDLPKKVRALALRHALSSKAKAS----------------T-LIVVDDI----KIE-D------ --HKTKLII--GGAED--V---NFGRAARAIPQID-V---------------LPVQGINVYDILRRDT----LVLTKAAV DALEPRLRKHYDEVV----RQKLIEEFGYKNPMEVPQITKIVINMGVG-ESTADSKKASVAAADLALIAGQKPVITKARK AIATFKVREGMPIGCKVTLRKQRMYEFMDRLITIALPRVRDFRGLNP-RSFDGRGNYALGLKEHLVFPEIS-----YDKA EQMWGMDIVVATT-----------------------AKTDAEAKALLAAFKFPFMSRVG-K--KPVPVPAGVTAT-V--- -T-G--Q-TVKMKGSKGELSFVV--PA-L--VNVAMKD-GA--IEV----Q-P-VNQSKPAR-SLWGTSRAQIANIAEGV SKGFEKKLEITGVGY--RAAMAG-KA--LKLS--LGYSHDIEYAI-P-A-GITIATP--K-PTEITISG-INRQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDVIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDVKRADGSVIRFDKNAAVLIN-NQKE-PIGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NQISDNPGA-TKDRMRVG-RGIGSGK-GKTAGRGVKGQKARTGVA-I--- --KGF-E-GGQMPLHRRLPK-RG--FNNVNLGRIVTVESLVAA-GIIAVK---------LLG--VGE-L-T-A-K-LSF- EVTRASKSAVEAVEKAGGSV-K---QFK--GRI---HGAA-KGGFELNFG----------QFGLKAV--EPERVTARQIE AARRAITREM------KRQGRVWIRVFPDVPVSSKPTEVRMGSGK---------GAPDYWAARVHP-GRIMFEV--DG-- VAENIAKEALRLGAAKLPIRTRV-VKLEALDRRKARVRRAL--RAAANGRPRLSVFRSSKQIYVQVIDD---V--AGKTL ASASSI-DKAL-KGEL----KTG-ADVAAATAVGKLVAER--AKAAG-VTKVIFDRSGYIYH--GRVKAVAEAAREGGLE F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAQMIRGKKVDTALAELQFS---------------------------------RKRISTEVKKCLESAIAN----A- ENNH-DLDVDDLVVSQAFVGKALVLKRFHARARGRGARILKPFSNLTIVVREAAKIKKGDKVVVLTGR------DS-GRS GEVIQVLPKEG--RAF--VRGINLVKKHQK----QT--QN--QE-GGIISKEAAIQLSNIA-VADAN--------GK--P --TRVGFRI---LE--------DGKVR---FAKTTG---DQI--MGQKVNPIGLRLG--IN-RTWDSRWFA------NKG D--YAKLMHEDVAIRAAL--MKQLK-----QAAVSKIVIERPH-R-KCRVTIHSGRPGVVIGKKGADIEKLRKLVGTMVT INIVEVRK---PEIDATLVADSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARQEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGIKVWVF-MVNDPVGDMLTRIRNGQLRRRNVVQT-PGSRLRASVLDVLKAEGYIRDYA ATD----L-GNG-----RTEFAIELKYY----DG-------R---PVIREIKRVSKPGRRVYSSVGELPHVADGLGVTIV STPQGVMADHEARERNVGGEVLCTVFMNGQNIRIRLKAFDHRILDASTKEIVSTAKRTGATIRGPIPLPTHIAKFTVNRS PHIDKKSR-EQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGTVVSDKGEKTIVVKVERRFTHPVMK KTVRRSKNYHAHDEG--NVAKVGQTVFIEECRPFSKTKTWKLVE--QAE------------------------------- -MARSL-WKGPFVDG-YLFKKAEAARG---SSRSE----VIKIWSRRSTILPQFVGLTFGVHNGQKHIPVYVTE-EMVGH KFGEFSPTRTFPGHA------A---DK----KAK------RR >ALPHA_Methylobacterium_sp_4-46 Concatenation of 2 sequences MALKTFKPVTPSLRQLVIVDRSE-LYKG------------KP-VKALTEGKISSGGRNNLGRVTVRF-RGGGHKRT---- LRNVDFK-RR-EF-AGKVGTVERIEYDPNRTAFIALVSYE-GGGQSYILAPQRVKAGDRVVSGE-Q-VD-IKPGNAMPIG NMPVGTIVHNVELKIGKGGALARSAGNYAQIVGR--DQGYVTLRLNSGEQRLVHGQCYATVGAVSNPDHMNISLGKAGRK -RWL-----GRR-P-HNRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGFPTKGKKTR-SNKR-TD-T-FIVSSR --------------------------------MRS---G-VIAQKVGMTRVFT-DAGE---------HVPVTVLKVDQCQ VVAHR----TVE----K--NGY--VALQVGV-------GK--AVSK----------AERGRFI----------------- ---AK-VEPKRKLAEFRV--------TEDALI-----PV---GA-EITA--D-H-FIPGQFVDVTGTTTGKGFAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHLGVERVTTQNLRVVRTDPERG---------------- ----------LILVEGA-VPGVAGGWIQIR--MKFEITT-LDGGEA-GSVEVNEAIF----GL-EP-RADLLQRCVRWQL AKRQAGTHKVKTRSE--------IS-RTTKKMY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGARAFGPV-V-RSHAHDLPKKVRALALRHALSAKARAA----------------S-LVVVDDV----RLE-D------ --GKTKLII--GGAED--E---NFGRAARNLPSID-V---------------LPVQGINVYDILRRDK----LVLTRAAV DALEPRLRKHYDEVV----RAKMIQEFGYTNPMQVPTIEKITINMGVG-ESTQDSKKATVAAEDLGLIAGQKPVITRARK AIATFKVRENMPIGCKVTLRRQRMYEFMDRLITIALPRVRDFRGLNP-KSFDGRGNYALGLREHLVFPEIN-----YDKA QNAWGMDIVVTTT-----------------------AKTDAEARALLKHFNFPFMSRVG-K--KPVTVPAGVTAT-V--- -D-G--Q-NVKIKGAKGELSFRV--PD-L--VEVSHAD-GA--ISV----Q-P--RSQKEAR-AMWGLSRAQVANLIEGV TKGFEKKLEINGVGY--RAAVAG-KV--LKLS--LGYSHDVEYEI-P-A-GITITTP--R-PVEIIVAG-IDKQRVGQIA AEIREYR------GPEPY---KGKGVKYSDEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDVRRPDGSVIRFDRNAAVLIN-NQKE-PIGTRIF GPVPRELR-ARNHMKIISLAPEVLMK-L--NEIRDNEGA-TKDRMRVG-RGIGSGK-GKTAGRGVKGQKARTGVA----- -IKGF-E-GGQMPLHRRLPK-RG--FNNVNVGRIVTVEALVAA-GVVSVK---------ILG--VGE-L-T-A-S-LTF- QVARASKSAVAAIEKAGGSV-K---QFK--GRI---HGTA-KGGTDLNFG----------SYGLKAL--EPERVTARQIE AARRAITREM------KRQGRVWIRIFPDVPVTQKPTEVRMGSGK---------GSPEYWAARVHP-GRVMFEI--DG-- VAEDIAREALRLGAAKLPVRTRF-IKIDLLDRRRARVRRAL--RAAANGRPRLSVFRSSKQIYVQVIDD---A--SGRTL AAASSL-DKDL-RARL----KTG-ADKAAALEVGKLVAER--AKAAG-VTKVIFDRSGYLYH--GRVKALADAAREGGLE F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAQLIRGKKVANALADLQFS---------------------------------RKRIAVEVRKCLESAIAN----A- ENNH-DLDVDDLVVKEAYVGKALVLKRFHARARGRGARILKPFANLTIVVREAAKVKKGDKVVVLTGR------DK-GRT GEVIQVMPKEN--RAL--VRGVNLVKRHQR----QT--QT--QE-GGIISKEAAIDLSNLA-VADPKD-------GK--P --TRVGFRI---LE--------DGKVR---FAKRSG---DLI--MGQKVNPIGLRLG--IN-RTWDSRWYA--------N KGEYARLMHEDVAIRQAL--MKQLK-----QAAVSKIVIERPH-R-KCRVTIHSGRPGVVIGKKGADIEKLRKLVGTMVT INIIEVRK---PEIDATLVADSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGIKVWVF-MITDPVGDMLTRIRNGQQRRRNVVQT-PGSKLRARILDVLKSEGYIRDYA TTD----Y-G-N----GRTEFAIELKYH----DG-------Q---PVIRSIERVSKPGRRVYSSVDTLPRVADGLGVTIV STPLGVMADHEARERNVGGEVLCKVFMNGQNIRIRLKAFDHRILDSSTREIVSTAKRTGAQVRGPIPLPTRIERFTVNRS PHIDKKSR-EQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVVSDKQDKTIVVKVERRFTHPVMK KTVRRSKNYHAHDEN--NAAKVGQTVFIEESRPFSKLKTWRLVEARDVA------------------------------- -MARSV-WKGPFVDG-YLLKKAETARG---STRAE----VIKIWSRRSTILPQFVGLTFGVYNGQKHIPVYVTE-EMVGH KFGEFSPTRTFHGHA------A---DK----KAK------RR >ALPHA_Methylocella_silvestris_BL2 Concatenation of 2 sequences MALKTFNPVTPSLRQLVIVDRSD-LYKG------------KP-LKQLTEGKSSSGGRNNNGRITVRF-RGGGHKQT---- YRIIDFK-R--RK-LDVAAKVERIEYDPNRTSFIALIRYA-DGEQSYIIAPQRLSVGDEVVSSQ-Q-AD-VKPGNAMPLA SMPVGTIVHNIEMKIGKGGAMVRSAGTFAQVVGR--DQGYVIIRLNSGEQRLIHGQCFATVGAVSNPDHMNASIGKAGRS -RWL-----GRR-P-HNRGVTMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-SNKSTTK---FIVTSR --------------------------------MRS---G-VIAQKLGMTRVFN-DGGE---------HVPVTVLKLDGCQ VVAHR----TKE----R--NGY--TALQLGI-------GR--AVSK----------AERGRFI----------------- ---AE-VEPKLKLAEFRV--------EESDLL-----PV---GA-EITA--D-H-FVVGQFVDVTGTSIGKGFAGPMKRW NFGG-LRATHGVSLSHRS-HGSTGGR-QDPG-KTFKNKKMAGHMGAERVTTLNLKVVQLDIERG---------------- ----------LILVEGA-VPGVAGGWIQVR--MKIDITS-LNGDSA-GSIDLDDSIF----GL-EP-RQDLIARMVRYQL AKRRAGTHKTKGRAE--------IA-RTGKKLY---------KQKGTGSAR--------HGS---AR-VP----QF---- RGGGRAFGPV-V-RSHAHDLPKKVRALALKHALSAKAQGG----------------G-IIVWSDA----SAT-D------ --AKTKLII--DGAEE--Q---NFALAARNIPQID-V---------------LPVQGINVYDILRREK----LVLTRAAI DALEPRLKKHYEEVV----RSQLIEQFGYKNPLEVPTIEKIVLNMGVG-EAVNDTKKVTLAAADLGLIAGQKPVITHARK AIATFKVRENMPIGAKVTLRKTRMYEFLDRLVTIALPRIRDFRGLNP-KSFDGRGNYAMGIKEHIIFPEIN-----YDQV ENVVGMDIIVCTT-----------------------AKTDEEARALLRAFNFPFMSRIG-K--KPVAIPSGVTAN-V--- -D-G--Q-LISVKGGKGQLSFAA--PE-D--VTVVLGD-GG--IEV----S-P-RNETKRAR-AMWGMTRSMVNNLVVGV SKGFERKLEITGVGY--KAAVSG-KN--LQLS--LGFSHDVTFPI-P-D-GISIVAA--K-PTEVAISG-IDKRQVGQIA SEIRALR------PPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AGVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDIKRADGSVIRFDSNAAVLIN-NQAE-PIGTRIF GPVPRELR-ARNQMKIISLAPEVLMK-L--NEIQDNPGS-SKSRMRVG-RGIGSGK-GKTCGRGVKGQKARTGVA-I--- --KGF-E-GGQMPLHRRLPK-RG--FYNINLGRLVTNESLIAS-GLISVK---------ILG--VGE-L-K-A-K-LSF- QVAAASKSAVAAIEAAGGSI-K---AFK--GRI---HGAA-KGGFELSFG----------QFGLKAL--EPERITARQIE AARRAMTRHM------KRAGRVWIRIFPDVPVSKKPTEVRMGKGK---------GAPELWAVRVAP-GRIMFEL--DG-- VPVDLAREALQLASAKLPIKTRF-IDNKATDRRRARVRRTL--RARAYGKPRLSVFRSSKQIYCQIIDD---E--AGLTL AAASSL-EKSA-RESL----KTG-ADVEAARAIGKLIAER--ATAAG-VTDVVFDRGSYLYH--GRVKALAEGAREGGLN F-------------------------------------------------------------DNE-AKAVARMLRISPQK LNLLAQLIRGKKVERALAELEFS---------------------------------RKRAAFDVRKTLESAIAN----A- ENNH-SLEVDDLVVAEAFVGKALVMKRFSPRARGRSGKIQKPFSHLTIVLREAAKIKKGDKVVVLVGR------DK-GRS GEVLQVIPKED--RAL--VRGVNLVKRHQR----QT--AQ--QE-AGIVSKEAAIQLSNLA-VADPKD-------GK--P --TRVGFKV---LE--------DGKVR---FAKRSG---DVI--MGQKVNPIGLRLG--IN-RTWDSRWFA------GKN E--YGKLLHEDMAIRAAL--MKTLK-----QAAVSKIIIERPH-K-KCRVTIHSARPGVVIGKKGADIDKIRKLVAKMVL INIVEVRK---PEIDATLVADSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADVDYGTATAHTAYGACGIKVWIFMAVNDPLGDMLTRIRNAQMRRKGKVQT-PGSRLRAHVLDVLQSEGYIRGYS TTE----Y-G-N----GRTEFEVELKYF----DG-------L---PVIREIQRVSKPGRRVYAAVDAMPRVANGLGITIV STPKGVMADHAAREANVGGEVLCRVFMNGQNIRIRLKAFDHRILDTSTKEIVSTAKRTGAHVRGPIPLPTKIEKFTVNRS PHVDKKSR-EQFEIRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVSDKQEKTIVVKVERRFTHPLLK KTVRRSKNYHAHDET--KAFKIGDTVSIEETKPMSKLKRWIVLPAAQAQ------------------------------- -MARSI-WKGPFVDG-YLLKKADASRA---TGRSE----VIKIWSRRSTILPQFVGLTFGVYNGHKHVPVNVTE-EMIGH KFGEFSPTRTFHGHS------A---DK----KAR------RG >ALPHA_Neorickettsia_sennetsu_Miyayama Concatenation of 2 sequences MPVKNLKPFNASSRGAVLVDYSE-LWRG------------SP-EKKLLLPKKSCSGRNNAGRITVRH-RGGRGKVR---- YRLISFS-RF-SS--GAPAVVERIEYDPNRTAFIALVRDFKTGLPSYIIAPEGLKKSDVLSTDV-F-DD-MAPGACMPLG KVPLGTTVHNVELKPGAGGQLVRSAGSSARVIAR--DGNYTLVTLPSGEKRLILSTCHATIGAVSNADRKNTKLGKAGRS -RWL-----GRR-P-SVRGVAMNPVDHPMGGGEGKT-S--GGRH-PVSP---WGFPTKGKKTR-DPNKLSS-K-FIKSKK --------------------------------SRV---G-LLLKKVGCTSVYD-DRFS---------LVPITLLQLEENV VLSAE------E----R--DGV--VIARVSF-------GT--RLKR----------PQSACLK----------------- ---LG-LEKGGRVVEFRV----------SPRF-----MPEPLGS--LTV--E-H-FRPGQYVDAVGTSIGKGFAGVMKRH NFAG-LRASHGVSISHRS-GGSTGQC-QDPG-KVFKGKKMAGHMGNARVTIQNLLVQLVDVENC---------------- ----------LIGVRGS-VPGCKNSYVLLKSSLEVGVLD-FGASSLAGSVAVDRALI----EA-PF-RPDLLSLVINWQL AKRRAGTHKTKGISE--------VS-GTTRKPY---------RQKGTGRAR--------QGS---LR-AP----QF---- RKGGIVFGPV-V-RQHGFSVNKKVRSLALRSALSMRFAEG----------------R-LFVLESS----RLG-E------ --SKAALIV--TEEKN--E---GLLRAASNLHWVK-V---------------LWGSSANVYDVVLHDF----VLLEKASV DVLV-MLESEYHKSA----LARVMKEVGVDSPVKAPRFEKVCLSVGLG-GASSDSKLLASAVEDLSLIAGQKAVVTVAKK SISSFKLRKGFPVGCRVTLRKRRMFDFINRLLYMALPDQKDFKGFTM-RNFDGHGNMAFGLTEHIVFPEVD-----FDKT YRIIGMNVVVVTT-----------------------ASTDQLARILLSCYGFPFMSRVG-E--SSIDI-SGLDCS-F--- -ERS----TGVVRFSSGEVSVSH-SLPGG--IFCEVSA-GR--IQL------S--AEDDSMS-MLLGLHRSLLNNIACGL RKKFQRRLVLNGVGY--KAEVRG-RY--LILY--LGYTHNIKYFI-F-D-AVSITAV--K-PTELLVES-SDKHVLGLVV SDLCSLR------RYDPY---KGKGIFPSDVVMPRKEAK----------MIKKETVLDVADNSGARKVLCIGIS---SKK T--ASIGDVITVSVKKCIPV-G-------KVSAGSIHRAVVVRVKK---RSSSSIVVFGDNAVVLLN-KQNE-MIGTRVF GPTDSLLR-NKGFAKISSLSQEVFIK-V--NDILLSLVT-RRSKRR-G-RGIGSGK-GKTCGRGLNGQGSRTGVT----- -LSRM-E-GGQQSFLRALPK-RG--QRPVSTGDIISKELMLKC-GLIKVK---------VLA--SVD-V-SLV-D-LKI- SSCEYDKISVSARRAFGLSE-K---FRK--VRF---SDAS-ARGSGLAFG----------EYGLKAI--GSARLNGRQIE SARRVITRIV------SKAGKLWINVFPGIPLTRKPTDVRMGGGK---------GSVDSYIFAISP-GRVLFEL--GG-- VDREKAKLALCKASAKLPFSTKF-VKRAFRVHYRKRGKLPL----------RLVVSRKNRNFHAQIIDD---T--SASTV YHVSTL-SKDFVRK------GGV-LNSSVVAELAEYFVSR--------IPE---------SLKGSKV------VFDSGAS AYHG----------------------------------------------LVALFAEKVRAC----MRAEYKNMKSSVQK VNLVADMIRGKGVDVARSQLLFL---------------------------------KKALAKPLSKVLMSSVAN----A- QNNF-GVDPDNLYVKEVFVGKGMSLKRFAARARGRSASIRKHYSNVSILLGVMKRIVSGDQVKVISGN------EA-GKV GVVRKVLYSSVGRRVI--VSDVN-VRRFVK----KT--QA-G---KKFDAKSYPIAVSNVA-LLA----------GD--G FVSKVGFKL----K--------DGKKR---IFKRTA---EFV--MGQKVNPVGFRLW--TH-GSHGSVWYS--------K SCDYAKTVAEDYFVTKYV--ESSFA-----HIGISKVIIKRKG-A-SCDITLHCMKPGLIIGKKGADLESFRLKLNKKPS LNVVEVKK---PNSSAVLVAKSIAFQLEKRSSFRRVIKKAIATVMRESDVKGVKVACSGRLSGAEIARTEVFKEGSIPL- -HTMRADIDYWVAEAHTTYGVIGVKVWIYMP-NSLIADAVARIRNGQMARLREVTI-YHSRVLVEIAALLKEEGYIVGYE VIE--IRP--------SVKRIIIRLKYY----CG-------Q---PVISKLKLFSRPGKRIYSRACEIPKFYGGLGISVL STSKGILPSYKAVSSNCGGELLFGVY--MKKIRIKLKSFDSGILHRSTKEIVMAAKRNGALVSGPIPLPTRVSRYTVNKS PHVDKKSR-EQFQLAVHKCLLELSSFNAHLLSTFTNFQLPAGVDISVEVALVLEGVAVRDSLSKTVKVRVTRKVSHPKYK KVLHLTKSYLAHDEA--NVVRAGQVVRIQAVRPISARKAWLVV------------------------------------- -MPRSV-WKGPFCDN-YVIK--LARRA---RGNPN---VLIKIRSRRSVILPAFVGYTFGVYNGKVFIPVKVNE-NMVGH KFGEFSPTRTFNGHS------G---DR----KVN------KK >ALPHA_Nitrobacter_hamburgensis_X14 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-VKALTEGKRGKGGRNNTGRITVRF-RGGGHKQA---- YRNVDFK-RG--K-EDVPAIVERLEYDPNRTAFIALIKYQ-DGEQAYILAPQRLAVGDTVVAGN-Y-VD-VKPGNVMPLG NMPVGTIVHNVEMKIGKGGQLARSAGTYAQIVGR--DHDYVILRLNSGEQRLVHGRCRGAIGAVSNPDHMNTSIGKAGRT -RWM-----GRR-P-HNRGVVMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-S-NKSTN-K-FILISR --------------------------------MRS---G-VIAQKVGMTRVFT-DAGE---------HIPVTVLRLSNCQ VLGHR----TSE----K--NGY--VALQLGS-------GA--RLPK----------AERGQFV----------------- ---AK-VEPKRKVAEFRV--------SEDSLI-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSVGKGFAGGMKRW NFGG-LRATHGVSVSHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGVDRVTTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGSKGGWIAVR--MELNVTT-LEGNAA-GSVQLSDGIF----GL-EP-RKDLIQRCVNWQL AKRQAGTHKTKGRAE--------IW-RTGKKMF---------KQKGTGNAR--------HGS---AR-VP----QF---- RGGGRAFGPV-V-RSHAHDLPKKVRALALRHALSAKAKDG----------------G-LIVIDSA----ELN-E------ --AKTKLIV--DGAAH--A---GFATAARNIPNID-V---------------LPIQGINVYDILRRRK----LVLTKAAV DALEPRLRVEYDKSI----RTKLTEQFGYVNVMEVPRLDKVVLNMGIG-EAVNDRKKAETAAGDLSLIAGQKALVTYSRV AISTFKLRENQPIGCKVTLRKAKMYEFIDRLINVALPRVRDFRGLNP-KSFDGGGNYSLGIKEHIIFPEID-----FDKA GESWGMDVTVCTT-----------------------AQTDDEARALLTAFNFPFMSRIG-K--RPVTVPSGVTAT-V--- -E-G--Q-TVRMKGPKGQLEFVV--HN-D--VEVKLEN-GA--VKV----A-P-RYETNRAQ-ALYGTARAQVANLVAGV TKGFEKKLEIVGVGY--RAALQG-KT--LQLA--LGYSHDVSYAI-P-E-GITIAVP--K-PTEITIAG-NDAQRVGQVA AEIRGYR------PPEPY---KGKGVKYADEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ATVGDIIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVAKDIRRADGSVIRFDRNAAVLIN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SDIADNAGS-RKKRMRIG-RGIGSGK-GKTGGRGGKGQTARSGVR----- -IKGF-E-GGQMPLHRRLPK-RG--FNNINLDRLVNAESLVKS-GVVRVR---------LLG--RGE-I-K-A-K-LTI- EVHGASKSAIAAVEKAGGTV-K---AHK--GRI---HGTA-SSGATLAFG----------QFGLKAM--APERISARQIE AARRALTRHM------KRAGRVWIRVFPDVPVSKKPAEVRMGSGK---------GAPELWVVRVKP-GRVLFEI--DG-- VGAQTAKEALTLAAAKLPIKTRF-VLKVTNARRKQRVRLSL--RRTANGRPRLSVFRSSKHIYAQVIDD---L--KGETL ASASSL-EKTM-RDAG----NTG-ANIDAAKAVGKLLAER--AVKNG-VKEVVFDRGSYLYH--GRVKALADAARESGLS F-------------------------------------------------------------ENE-AKAIARMLRVSPQK LNLVAQLIRGRKASAALADLQFS---------------------------------RKRIAGDVKKCLESAIAN----A- ENNH-DLDVDELVVAQAFVGNGMVMKRFAPRGRGRSGRIYKPFSQLTIVVRQAAKIRKGDKVIVLSGR------DK-GRT GEVFEVRPAES--RAL--VRGVNMVKRHQK----QS--QS-Q-E-GGIISKESPVHLSKIA-IVG-KD-------GK--P --TRVGFKI---QA--------DGKVR---VAKRSG---AEI--MGQKINPIGLRLG--IN-RTWDSRWYA------GKN E--YGRLLHEDVRIRELL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKRVADIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRNKSKVST-PGSRMRANVLEVLKSEGYIRGYA SVE--HSS--------GRSELEIELKYF----DG-------E---PVIREIERISRPGRRVYASVKNLPRVKNGLGISVL STPKGIMADHEARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQAKTVVVRVDRRFTHPLYK KTIRRSKNYHAHDEN--NEFKPGDMVWIEESKPISKLKRWTVVR--KKT------------------------------- -MVRSV-WKGPFVEG-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLVFGVYNGHKHVPVSVNE-EMVGH KFGEFSPTRTFHGHS------G---DK----KAK------RA >ALPHA_Nitrobacter_winogradskyi_Nb-255 Concatenation of 2 sequences MALKTYNPTTPGQRQLVMVDRSA-LYKG------------KP-VKTLTEGKRGKGGRNNTGRITVRF-RGGGHKQA---- YRNVDFK-R--GK-TDVPAVVERLEYDPNRTAFIALIKYQ-DGEQAYILAPQRMAVGDTVVAGN-Y-VD-VKPGNVMPLG NMPVGTIVHNVEMKIGKGGQLARSAGTYAQIVGR--DQDYVILRLNSGEQRLVHGRCRGAIGAVSNPDHMNTSVGKAGRT -RWM-----GRR-P-HNRGVVMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-SNKS-TN-K-FILISR --------------------------------MRS---G-VIAQKVGMTRVFT-EAGE---------HIPVTVLKLSNCQ VLGHR----TSE----K--NGY--VALQLGS-------GA--RMPK----------AERGQF------------------ ---VAKVAPKRKVAEFRV--------SEDSLI-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSVGKGYAGGMKRW NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGVDRITTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGSKGGWIAVR--MELNVTT-LEGKAA-GSVHLSDGIF----GL-EP-RKDLIQRCVNWQL AKSQAGTHKTKGRAE--------IW-RTGKKLF---------KQKGTGNAR--------HGS---AR-AP----QF---- RGGGRAFGPV-V-RSHAHDLPKKVRALALRHALSAKAKDG----------------G-LIVIDSV----ELK-E------ --AKTKLII--DGAQH--A---GFATAARNIPNID-V---------------LPIQGINVYDILRRQK----LVLTKAAV DALEPRLRAEYDKSI----RSRLTEQFGYVNVMQVPRLDKVVLNMGIG-EAVNDRKKAEAAAGDLSLIAGQKAVVTYSRV AISTFKLRENQPIGCKVTLRKTKMYEFIDRLVNVALPRVRDFRGLNP-KSFDGRGNYSLGIKEHIIFPEID-----FDKV GESWGMDVTVCTT-----------------------AQTDDEARALLTAFNFPFMSRIG-K--RPVTVPSGVTAT-V--- -E-G--Q-TVKMKGPKGELRFVV--HD-D--VEVKLED-GA--VKV----A-P-RYETKRAQ-ALYGTARAQVANLVAGV TKGFEKKLEIIGVGY--RAALQG-KS--LQLA--LGYSHDVNYAV-P-E-GITIAVP--K-PTEITITG-NDAQRVGQVA AEIRGYR------PPEPY---KGKGVKYADETIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ATVGDIIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVSKDIRRADGSVIRFDRNAAVLIN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SDIADNAGS-RKKRMRIG-RGIGSGK-GKTGGRGGKGQTARSGVR-I--- --NGF-E-GGQMPLHRRLPK-RG--FNNINLDRLINAESLVKS-GVVRVR---------LLG--RGE-I-K-A-K-LTV- EVHGASKSAIAAVEKAGGTV-K---AHK--GRI---HGVA-SSGATLAFG----------QFGLKAM--APERITARQIE AARRALTRHM------KRAGRVWIRVFPDVPVSKKPAEVRMGSGK---------GAPELWVVRVKP-GRVLFEI--DG-- VAPQTAKEALTLAAAKLPIKTRF-VLKITNARRKQRVRLSL--RRIANGRPRLSVFRSSKHIYAQVIDD---L--KGETL ASASSL-EKAM-RDAG----NTG-ADIDAAKAVGKLVAER--AVKNG-VKEVVFDRGGYLYH--GRVKALADAARESGLS F-------------------------------------------------------------ENE-AKAIARMLRVSPQK LNLVAQLIRGRKASAALADLQFS---------------------------------RKRIAGDVKKCLESAIAN----A- ENNH-DLDVDELIVSEAFVGNGMVMKRFAPRGRGRSGRIYKPFSQLTIVVRQAAKIRKGDKVIVLSGR------DK-GRT GEVFEVRPAEG--RAL--VRGVNIVKRHQK----QT--QN-Q-E-GGILSKESPIDLSNIA-IVG-KD-------GK--P --TRVGFKI---QA--------DGKVR---VAKRSG---AEI--MGQKINPIGLRLG--IN-RTWDSRWYA------GKA E--YGRLLHEDVKIRELL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKRVADIVV LNIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRSKPKVST-PGSKMRANVLEVLKSEGYIRGYA SVE----H-S-S----GRSELEIELKYF----DG-------E---PVIREIERVSRPGRRVYASVKNLPRVNNGLGISVL STPKGIMADHEARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYK KTIRRSKNYHAHDEN--NEFKPGDMVWIEESKPISKLKRWTVVRGEQRK------------------------------- -MVRSV-WKGPFVEG-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLVFGVYNGQKHVPVSVNE-EMVGH KFGEFSPTRTFHGHS------G---DK----KAK------RS >ALPHA_Novosphingobium_aromaticivorans_DSM_12444 Concatenation of 2 sequences MALKSYNPTSPARRGLVLVDKSA-LWKG------------KP-VKALTEGKRKTGGRNNKGHVTSRG-IAGGHKQK---- YRYVDFK-R--RK-WDMPATVERLEYDPNRTAFIALVKYE-DGELAYILAPQRLGVGDQVIAGE-K-TD-VKPGNAMLLS QMPVGTIIHNVEMKPGKGGQIARSAGTYVQLVGR--DRGMVIVRLNSGEQRYLRGDCMGTVGAVSNPDNGNQNLAKAGRN -RWL-----GKR-P-LTRGVAKNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGARTR-HNKA-TD-K-MIIRSR --------------------------------MRT---G-VIAKKVGMTRLFQ-EDGR---------HVPVTVLSLENCQ VVSVR----TAE----R--DGY--VALQLGA-------GE--AVAK----------PQREHFK----------------- ---AE-VPLKMEVAEFRV--------ADDALL-----DV---GS-TIAA--S-H-FVPGQYVDITGQTQGKGFQGAMKRW GFGG-MRATHGVSISHRA-HGSTGNR-QDPG-RVFKNKKMAGHMGDRQRTQQNLEVVRTDDERG---------------- ----------LIFVKGS-VPGSKNAWLLVR--MKVQVLN-LDGTAGKGEVELSDDVF----GL-EP-RADILHRVVTWQL ENRRGIARKARERSD--------VA-RTGKKFG---------RQKGGGTAR--------HGD---RK-AP----IF---- IGGGKAHGPR-V-REFNISLNKKVRALGLKMALSSKAKAG------------------LVVVDNL----DVD-------- --AKTKLVI--DGEGN--D---NFAKAARNIVGVN-V---------------LPAIGANVYDILKHDT----LVLTRAAV EKLEPRLKGKYDAEI----AAAMQAKFGYKNALEIPRIEKITLNMGVG-EASQDKKKVTTAAAEMELIAGQKPVITKAKK SIAQFKLREGMPIGCKVTLRRERMYEFLDRLITIAMPRIRDFRGLNP-KSFDGRGNYAMGLKEQIIFPEIS-----YDQI EKVRGMDIIVTTT-----------------------AKTDDEARELLRLFGFPFMSRIG-K--RPVTIPSGVTAN-I--- -A-D--G-VLTVKGPKGTLTLTL--RD-E--ISYTVDG-DT--ILV----K-P-ANDTKGAR-AFWGMQRTLVDNLVTGV TQGYTKVLEITGVGY--RANAQG-KN--LKLQ--LGYSHDVDFPV-P-E-GIEIKTP--D-NTTVEISG-IDKQKVGQVA AEIRRWR------KPEPY---KGKGIKYRGEFIFRKEGK----------MIQMQSNLDVADNSGAKRVQCIKVLG-SKRR F--AGVGDIIVVSVKEAQPR-A-------RVKKGDVHRAVIVRTKKDVRRTDGSVIRFDSNAAVLVG-KNEE-PIGTRIF GPVVRELR-GKGFMKIISLAPEVLMK-L--NEISDNNGA-RKGRMRVG-RGIGSGK-GKTAGRGQKGAKARSGVS----- -INGF-E-GGQMPLHMRLPK-RG--FNNVNLGMVVDHAALKAA-GLARVR---------LLA--KGE-L-T-S-K-VAF- KVAGASKGAFAAVEKAGGSI-K---AFK--GRI---HGLA-KGGTDLNFG----------SYGLKAL--EPERVTARQIE AARRAITRHI------RRQGRLWIRVFPDVPVSKKPAEVRQGKGK---------GSIEYWAARVKP-GRILFEL--DG-- VPGPLAAEAFSRAAMKLPIKTKV-VKLSLFERRRRRVRTAL--KARSGGRPRLSVHRSGRHIYAQIIDD---A--AGRTL AAASTL----V-KGDK----SIG-ANVDAAAKVGAEIAEK--AKAAG-ITTVVFDRGGFLFH--GRVKALADAAREGGLE F-------------------------------------------------------------DKE-ALSVGTQIRGSAQK LNLVAGLIRGKRAEDAMNILAFS---------------------------------KKAMAVDARKVLASAIAN----A- ENNH-NLDVDALVVAEASVGKSITMKRFHTRGRGKSTRILKPFSRLRIVVREAAKIKKGDTVVVRSGK------DK-GRS GTVLQVLPKDE--KVV--VQGVNIAARHRK----PS--QQ-NPQ-GGIDRFEAPLHISKVS-VAD-KD-------GK--P --TRVRFET----K--------DGKVR---VAVKSG---ETI--MGHKSNPIGLRLQ--IN-RTWDSRWYA------EGR N--YAQMLEEDLKIRKYI--VENLP-----QAAISKVVIERPA-K-LCRVSIYAARPGVIIGKKGADIEKLRSKLATMVK LNIVEIRK---PEIDSKLVAQGVADQLVRRVAFRRAMKRAVQSALRL-GAEGIKITCGGRLGGAEIARVEWYREGRVPL- -HTLRANIDYAEAEAHTAYGVIGIKVWIFMAMTDPLGDMLTRIRNGQQAKKDSVLS-PASKLRAHVLEVLQREGYIRGFS EDT----T---G----VHPQLRIELKYF----EG-------Q---PAIKHVARVSKPGRRVYSGSKELPVIRNGLGITIV STPKGVLSDAEARAANVGGEVLAEVFMEAQNIRIRLKAFDHRVLDQATGEIADTARRTGALIRGPIPLPTRIEKFCVNRG PHIDKKSR-EQFEVRTYKRLLDIVQPNAATVDALMKLDLAAGVNVEIKLKRILVGTVVSDKTDKTVVVKVERKVKHPLYG KIIRRSKKYHAHDEA--NAFKTGETVRIEETAPISKLKTWKVIDRVQAG------------------------------- -MARSV-WKGPFVDL-HLLKKAEAAQD---AGSRA---GPIKTWSRRSTIIPQFVGLTFNVYNGQKFIPVSVSE-EMVGH KLGEFAPTRNFPGHA------A---DK----KGK-------R >ALPHA_Ochrobactrum_anthropi_ATCC_49188 Concatenation of 2 sequences MALKHFNPITPGQRQLVIVDRSG-LYKG------------KP-VKSLTEGLSKKGGRNNTGRITVRF-QGGGHKRT---- YRFIDFK-RR--K-LDVVGTVERLEYDPNRTAFIALIRYE-DGELAYILAPQRLAVGDKVVAGN-S-VD-VKPGNAMPLA SMPVGTIVHNVELKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVPGACFASVGAVSNPDHGNINDGKAGRS -VWR-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-S-NKSTD-K-FIMRSR --------------------------------MRS---G-VIAQKLGMTRVYN-DAGE---------HVPVTVLRMENCH VVAQR----TVE----K--NGY--TAVQLGV-------GL--ATSK----------AMRGHFK----------------- ---AE-VEPKAKVAEFRV--------SPDNLL-----EV---GA-EITA--E-H-FVAGQKVDVTGTSIGKGFAGVMKRH NFAG-HRASHGNSITHRA-HGSTGQR-QDPG-KVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRG---------------- ----------LILVRGA-VPGSKGAWIIVR--MDLTITT-LEGKDA-GKVKLNEEIF----GL-DP-RDDILQRVVRWQL ARRQQGSHKAQGRGD--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGQAHGPV-V-RSHDHDLPKKVRALGLRHALSAKAKAS----------------D-LIIIDDL----AAT-E------ --AKTKLVI--GGAED--V---NFQRAASNIPNID-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRFKKLYNENI----RKALLEEFKYDNEMQIPRITKVVLNMGVG-EATGDSKKPAVAAEDLGLIAGQKAVITRARN SIATFKLREGMPIGTKVTLRQDRMYEFLDRFITIALPRVRDFRGLNP-KSFDGRGNYAMGIKEHIVFPEIN-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARALLRAFNFPFMSRIG-K--KPVPVPAGVTAS-V--- -D-G--Q-IVKAKGAKGELSFVV--HD-E--VLVKMED-GA--VSV----D-P--RDQKEAR-SKWGMSRTMISNIFVGV KDGFEKKLEISGVGY--RAAMQG-KN--LQLS--LGFSHEVVYDV-P-A-GITVAVP--K-PTEIVVTG-IDKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGEKIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NDLRDKPGS-VKARKRVG-RGIGSGT-GKTGGRGVKGQKSRSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FTNVSLGRVVNLDSLKAA-GVIRVR---------ILS--DGE-L-K-A-K-VAF- EVAGASKAAVEKIEKAGGSI-K---QFK--GRI---HGNS-KGGTDLNFG----------AFGLKAV--EPERVTARQIE AARRAITRHM------KRAGRVWIRIFPDLPVTSKPTEVRMGKGK---------GSVDYWACRVAP-GRVMFEL--DG-- VPEDVAREALRLGAAKLPIKTRF-IPKETLQRRAARVRRQV--KAVANGRPRLSVHRSSKNIYVQVIDD---V--RGVTI AAASTL-DGDL-KGKL----KTG-ADSAAAAAVGKLVAER--AVKAG-VSEVVFDRGAFIYH--GRVKALAEAAREGGLS F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVASMIRGKKVNAALADLTFS---------------------------------RKRIADTVKKTLQSAIAN----A- ENNH-DLDVDSLIVAEAYVGKSIVMKRFHVRGRGRASRIEKPFSHLTIVVREMQKIRKGDSVVVLSGK------DK-GRK GEVLKVMPKDE--QAL--VRGINVVKRHQR--------QTQTQE-AGIISKEAPIHLSNLA-IADPKD-------GK--P --TRVGFRV----E--------DGKVR---VAKRSG---ALI--MGQKINPIGLRLG--IN-RTWDSRWYA------NTG E--YGKLLHEDVKIREFL--TEELK-----QAAISKIVIERPH-K-KCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTS LNIVEVRK---PEIDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGTAEAKTAYGICGVKVWVFMSVSDPIGDMLTRIRNAVGRKKTKVST-PASKLRARVLDVLQSEGYIRGYT QSE--FVN--------GKAEIEIELKYY----EG-------V---PVIRELTRVSKPGRRVYVSVKSIPQVANGLGISIL STPKGVMADHEAREQNVGGELLCRIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQ KTVRQSKKYKAHDEN--NQFKVGDLVSIQESAPISKDKRWVVLT-NEAA------------------------------- -MARSV-WKGPFVDG-YLLTKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSISE-EMVGH KFGEFAPTRTYYGHG------A---DK----KSK------RK >ALPHA_Oligotropha_carboxidovorans_OM5 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-LKKLTEGKHSNGGRGNTGRITVRF-RGGGHKQT---- YRLIDFK-RT--K-VDVPATVERLEYDPNRTAFIALIKYA-DGELSYILAPQRLAVGDTVVAGS-Y-VD-VKPGNAMPMG NMPVGTIVHNVEMKIGKGGQMARSAGTYAQIVGR--DHDYVILRLNSGEQRMVHGRCMATIGAVSNHDHMNTSIGKAGRT -RWL-----GRR-P-HNRGVVMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-S-NKSTN-K-FILISR --------------------------------MRS---G-VIAQKVGMMRVFT-EAGE---------HIPVTVLKLGNCQ VVGHR----TKD----K--NGY--TALQLGA-------GA--RMPK----------AERGQF------------------ ---VAKVEPKRKVAEFRV--------SEDAII-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSIGKGYAGGMKRW NFGG-LRATHGVSVSHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGVDRITTLNLRVVQTDVERG---------------- ----------LLLVEGA-VPGSKGGWITVR--MELNVTT-LEGKAA-GSVNLSDTIF----GL-EP-RTDIIQRVVNWQL AKRQAGTHKTKGRAE--------IA-RTGKKMY---------KQKGTGGAR--------HGS---AR-VP----QF---- RGGGRAFGPV-V-RSHAYDLPKKVRALGLRHALSAKAKDG----------------S-LVVLDNA----ELK-D------ --AKTKLIV--DAEVN--N---GFAQAARNIPHID-V---------------LPIQGINVYDILRRQK----LVLTKAAV DALEPRLREVYDRDI----RSKLTEQFGLTNVMQVPRLDKVVINMGVG-EAVNDRKKVELAAGDLALIAGQKPIVTHSRK AIATFKLREGQAIGAKVTLRKAKMYEFIDRLINVALPRVRDFRGLNP-KSFDGRGNYSLGLKEHIVFPEID-----YDKS GESWGMDITVCTT-----------------------AATDEQARALLTAFNFPFMSRVG-K--RPVAIASGVTAN-V--- -E-G--Q-TVKVKGPKGTRSFTV--HD-D--VSVELKD-NV--IRV----A-P-RFETKRAQ-SLYGTARAQIANLVEGV TKGFEKKLEITGVGY--RAALQG-KN--LQLS--LGYSHDVVYPV-P-E-GITITVP--K-PTEITVAG-IDSQRVGQVA AEIRGYR------PPEPY---KGKGVKYANEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRR Y--ATVGDIIVVSVKEAIPR-G-------KVKKGDVMKAVVVRVAKDIRRADGSVIRFDRNAAVLVN-NQSE-PVGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIADNEGS-RKKRTRVG-RGIGSGK-GKQSGRGGKGQTARSGVR----- -IKGF-E-GGQMPLHRRLPK-RG--FNNVNLDRLINAEALVKS-GVLRVR---------LLG--RGE-L-K-S-K-VAI- EVHGATKSAIEAVEKAGGSV-K---AHK--GRI---HGVA-SSGATLSFG----------QFGLKAM--APERITARQIE AARRALTRHM------KRVGRVWIRVFPDVPVSKKPAEVRMGSGK---------GSPELWVVRVKP-GRILFEI--DG-- VNDQIAREALTLAAAKLPIKTRF-VLKITNARRKQRVRIAL--RRAAGGRPRLSVFRSSKHIYAQVIDD---Q--KGETL ASASSL-EKTM-REGG----KTG-ANIDAAKAVGKLLAER--AVKNG-VKEVVFDRGGYLYH--GRVKALADAARESGLS F-------------------------------------------------------------ENE-AKAVARMLRVSPQK LNLVAQLIRGKKAASALADLQFS---------------------------------RKRIAVDVKKCLESAIAN----A- ENNH-DLDVDALVVSEAHVGNGMVMKRFAPRGRGRSGRIYKPFSQLTIVVRQAAKIRKGDKVIVLTGR------DK-GRT GEVFAVRPSEG--RAL--VRGVNMVKRHQK----QT--PQ-Q-E-GGIISKESPIHLSNLA-LLD-KD-------GK--P --TRVGFKI---GK--------DGKVR---IAKSSG---AEI--MGQKINPIGLRLG--IN-RTWDSRWFA------GKG D--YAKLLHEDVRIREVL--MKELK-----QAAVARIVIERPH-K-KCRVSVYSARPGVVIGKKGADIDKLKKKVAEIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAQGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYGVATAFTTFGTCGVKVWLFMSTHDPISDLITRIRNAQMRSKSKVST-PGSKMRASVLEVLKSEGYIRGYA SVE--HAS--------GHNELEIELKYF----DG-------E---PVIREIERVSKPGRRVYASVKNLPRVNNGLGISVL STPKGIMADHAAREANVGGEVLFTVFMNGQNIRIRLKAFDHRVLDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQDKTVVVRVDRRFTHPIYK KTIRRSKNYHAHDEN--NEFKAGDTVWIVESKPLSKLKRWTVVQ--EKT------------------------------- -MVRSV-WKGPFVEG-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLTFGVYNGQKHVPVAVNE-EMVGH KFGEFSPTRTFHGHA------G---DK----KAK------K- >ALPHA_Orientia_tsutsugamushi_Boryong Concatenation of 2 sequences MPLKVYNSVTQSLRQVVQVDKSE-LWKG------------RP-LKKLAKGISKTGGRNNLGRITIWH-RGKGHKQL---- YRMIDFK-RR--V-FDIYATVERIEYDPNRTAFIALIRYD-DGKFSYILSPRNLNVGDKIISSD-K-AE-INVGNCLSLE VIPVGTIIHNIEIKPGKGGQIARSAGTYAVLLNK--DSGYAQIKLRSGEVRRISLASRATVGSVSNIDHKNISYGKAGRV -RWL-----GRR-P-VVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVTP---WGKKTKGKKTR-K-NKFTS-R-FIVKRR --------------------------------ARS---G-LIAEKLGMSSKFD-ESGR---------KVAITLLKVDVCQ VLWHK----LVS----K--DGY--NAVILGY-------KN--IVKK----------PMHSIFR----------------- ---AK-IEPKAIIKEFKV--------AEDKML-----EI---AS-ILDA--S-Y-FRVGQYVDVRGVTIGKGFAGAMKRH GFRG-LEASHGVSISHRS-HGSTGNR-AYPG-RTFKNKKMAGHMGVRFATIQNLRVDSVDLEKR---------------- ----------LLVIQGS-IPGKSGSIVYIT--MKVKVYN-LLQEIE-KEVELNPSVF----CL-KY-RPDIIKLVIDWQL AKRMSGTHCTKTISG--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGISHGPV-V-RSHEFDVPKKIRKQALKYALSYKLSVN----------------K-LIVVDDF----NIG-S------ --NKTAFCI--DQNVD--R---NFFLASRNLFNLN-V---------------VAQIGANPYDIMKHDC----VMVTLSAA KSLELSFEELSFKEIKEKERQELQKKFGYSNNHQTPRIKKIVVTMCVG-DAVVDSKIIYYVKKCMAMITGQEPGLIKAKK SIAAFKLRKGMPIACKVTLRKKRAEDFIRRLVFEVFPRIKDFKGFSI-KSFDREGNFSFGIKDIRVFIEIEDEQKKKDVI DKEIGIGIHIHTS-----------------------TKSLLKAKALLKMRDIPFMSRIG-K--LVVMVPAGVVVD-V--- -N-N--L-SIAVSGPKGKLLKSF--LG-N--ITILKEN-DK--III----R-P-LSGDKHSR-AMWGTARSIINNMVKGV NSGFTKELEINGVGY--AASLKS-DY--LNLA--LGKSHSTKIKV-P-S-NIQVTVP--K-TNVIYLFS-IDKQALGQFA ALIIKQR------PAEHY---KEKGIKIKGQYVQLKESK----------MIQMQTILNVADNSGAKKVMCIKVLG-THHM I--AHLGDVIVVSIKSSIPK-G-------KVKKGEVCKALIIRTKCGVTRSDGSNIKFDSNDVVLLN-KQGE-PFGTRIF GSVPRELR-VKKFSKIVSLAEEVLMK-L--NTLFNLNGA-KKCSKRIG-RGIGSGK-GKTCGRGAKGQKSRAKVA----- --RGF-E-GGQTPLIKRLPK-RG--FKSINIITIIDKLLLLKL-KMLKIKLLWANPSSLVLSSEDISLL-TKL-D-LQF- NLDEYSISARKNIIKLGMKV-K---AQK--GRV---ASKA-KAGTMIAFG----------EFGLKSL--DSCRITSRQIE AARRAAVRCM------KRQGKFWINIFPSIPVSKKPTEVRMGKGK---------GATEFFAARVAV-GRILFEL--DG-- VSESIAIKALELAGAKLPVRTKI-VSKDRFIIRKNRVRAKI-AKLSGGCYPRLSVFKSNRHIYAQVIENIGSN--KSNTI AAASTL-DKDIFTESK----YYK-CNIQYAKKVGQLLAER--ANSKG-ITSVVFDRGGYKYH--GVIKALADGAREK-LN F-------------------------------------------------------------KKS-AKATLRMIKISPRK LNLITGLIRNLKVSDAIMQLKFS---------------------------------KKRAAVDVKKCLQSAIAN----A- ENND-GLDIDNLVVLEAIVGKGSVMKRLVPRARGKAFRIKKFFSNLYITVSEKIRIKTGDKVQVITGK------DK-GKR GIVIKVLASLS--RVI--VKGINLARKHVK----AN--KN-DVS-GGIINKELPIHISNVA-YVDSSS-----------N LITKITYTK---LD--------DKKVR---VSKRSG---EIL--MGQKVNPCIFRTGPNLP-RNWESVLYA------K-N N--YSDFLLKILKIRKII--NTEYS-----FAQITKILIEWPSSK-NIVVNIYAKKIGVIIGKSGGDIEKLKQNIAKIVS INIREVKK---PELEEAFIAQTIAQQLERRQSFKKVMKKAIHASMKQ-GAKGIKIICSGRLGGVEIARSESYKEGRVPL- -QTIRADIRYAFAEAITTYGVIGVKVWVYMSMSDTLADMLTRIRNAQRSRLMYVNV-PSSRRREAILDVLVKEGFIHSFL IHE--VRN--------GIKEINIKLKYS---PKG-------E---SNIKEINRVSTPGKRVYLSIKKLRPYYNNMGIYII STSKGIMSDREARKLGVGGEVICKVFMSSKDIRIRLKSFDHALLDRTTFEIVRLAKSAGAKVKGAVSLPRRIQYFTFNKS PHIYKKSR-EQFEIRTHKRLIVIASSTPQTIEALMKMTLAPGVDVQIN-RRVLQGQVISAKSDKTIIVSVERRFKHPMYH KTVKIAKKYAVHDPD--NLYNQGDKVKIIESRPISKTKCWRVIE--DKG------------------------------- -MARSI-WKGPFVRE-SLIKKVNKLIE---SGKSS----VIKTWSRESAIIPLFVRFVFAVHNGNKFIPVVITE-EMVGR KLGEFAPTRTFYGHA------A---DR----KVK------RK >ALPHA_Orientia_tsutsugamushi_Ikeda Concatenation of 2 sequences MALKVYNSVTQSLRQVVQVDKSE-LWKG------------RP-LKKLAKGITKTGGRNNLGRITIWH-RGKGHKQL---- YRMIDFK-RR--V-FDIYATVERIEYDPNRTAFIALIKYD-DGKFSYILSPRNLNVGDKIISSD-K-AE-INVGNCLPLE VIPVGTIIHNIEIKPGKGGQVARSAGTYAVLLNK--DSGYAQIKFRSGEVRRISLASRATVGSVSNIDHKNISYGKAGRV -RWL-----GRR-P-VVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVTP---WGKKTKGKKTR-K-NKFTS-R-FIVKRR --------------------------------MKNARSG-LIAEKLGMSSKFD-ENGR---------KVAITLLKVDVCQ VLWHK----LVS----K--DGY--NAVILGY-------KN--IVKK----------PMRSIFR----------------- ---AK-IEPKAVIKEFKV--------AEDRML-----EI---AS-ILDA--S-Y-FRVGQYVDVRGITIGKGFAGAMKRH GFRG-LEASHGVSISHRS-HGSTGNR-AYPG-RTFKNKKMAGHMGVKFATIQNLKVDSVDLEKR---------------- ----------LLVIKGS-IPGKSGSIVYIT--MKVKVYN-LLQEIE-KEVELNPSVF----CL-KY-RPDIIKLVIDWQL AKRMSGTHCTKTISG--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGISHGPV-V-RSHEFDVPKKIRKQALKYALSYKLSVN----------------K-LIVVDDF----NIG-S------ --NKTAFCI--DDQND--R---NFFLASRNLFNLN-V---------------VAQIGANPYDIMKHDC----VMVTLSAA KSLELSFEELSFKEIKEKERQELQKKFGYSNNHQTPRIKKIVVTMCVG-DAVVDSKIIYYVKKCMAMITGQEPGLIKAKK SIAAFKLRKGMPIACKVTLRKKRAEDFIRRLVLEVFPRIKDFKGFSI-KSFDKEGNFSFGIKDIRVFIEIEDEQKKKDVI DKEIGIGIHIHTS-----------------------TKSLLKAKTLLKIRDIPFMSRIG-K--LVVMVPAGVIVD-V--- -N-N--L-SIAVSGPKGKLLKSF--LG-N--ITILKEN-DK--IIV----K-P-LSGDKHSR-AMWGTARSIINNMVKGV NSGFTKELEINGVGY--SASLKG-DY--LNLA--LGKSHSTKIKV-P-S-NIQVTVP--K-TNVIYLFS-IDKQALGQFA ALIIKQR------PAEHY---KEKGIKIKGQYVQLKESK----------MIQMQTILNVADNSGAKEVMCIKVLG-THHM I--AHLGDVIVVSIKSSIPK-G-------KVKKGEVCKALIIRTKCGVTRHDGSNIKFDSNDVVLLN-KQGE-PFGTRIF GSVPRELR-VKNFSKIVSLAEEVLMK-L--NTLFNLNGA-KKCSKRIG-RGIGSGK-GKTCGRGAKGQKSRAKVA----- --RGF-E-GGQTPLIKRLPK-RG--FKSINIITIIDKLLLLKL-KMLKIKLLWANPSSLVLNSEDISLL-TKL-D-LQF- NLDEYSISARKNIIKLGMKV-K---AQK--GRV---ASKA-KAGTMIAFG----------EFGLKSL--DSCRITSRQIE AARRAAVRCM------KRQGKFWINIFPSIPVSKKPTEVRMGKGK---------GATEFFAARVAV-GRILFEL--DG-- VSEGIAIKALELAGAKLPVRTKI-VSKDRFIIRKNRVRAKI-AKLSGGGYPRLSVFKSNRHIYAQVIENIGSN--KSNTI AAASTL-DRDI-FTEL----KYYKCNIQYAKKVGQLLAER--ANSKG-ITSVVFDRGGYKYH--GVIKALADGAREK-LN F-------------------------------------------------------------KKS-AKATLRMIKISPRK LNLITGLIRNLKVSDAIMQLKFS---------------------------------KKRAAVDVKKCLQSAIAN----A- ENND-GLDIDNLVVLKAIVGKGSVMKRLVPRARGKAFRIKKFFSNLYITVSEKIRIKTGDQVQVITGK------DK-GKR GIVIKVLANLS--KVI--VKGINLAQKHVK----AN--KN-GVS-GGIISKELPIHISNVA-YVDSSS-----------N LITKITYTK---LD--------GKKVR---ISKRSG---EIL--MGQKVNPCIFRTGPNLP-RNWESVLYA------NKN N--YSDFLLKILKIRKII--NTEYS-----FAQITKILIEWPSSK-NIVVNIYAKKIGVIIGKSGGDIEKLKQNIAKIVS INICEVKK---PELEEAFIAQTIAQQLERRQSFKKVMKKAIHASMKQ-GAKGIKIICSGRLGGVEIARSESYKEGRVPL- -QTIRADIRYAFAEAITTYGVIGVKVWVYMSMSDTLADMLTRIRNAQRSRLMYVNA-PSSRRKEAILDVLVKEGFIHSFL VHE----V-R-N----GVKEINIKLKYS---PKG-------E---SNIKEINRVSTPGKRVYLSIKKLRPYYNNMGIYII STSKGIMSDREARKLGVGGEVICKVFMSSKDIRIRLKSFDHALLDRTTFEIVRLAKSAGAKVKGAVPLPRRIQYFTFNKS PHIYKKSR-EQFEIRTHKRLIVIASSTPQTIEALMKMTLAPGVDVQIN-RRVLQGQVISAKSDKTIIVSVERRFKHPVYH KTVKIAKKYAVHDPD--NLYNQGDKVKIIESRPISKTKCWHVIE--DKG------------------------------- -MARSI-WKGPFVRE-SLIKKVNKLIE---SGKSS----VIKTWSRESAIIPLFVRFVFAVHNGNKFIPVVITE-EMVGR KLGEFAPTRTFYGHA------A---DR----KVK------RK >ALPHA_Paracoccus_denitrificans_PD1222 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKSLTEGLTKNGGRNNTGRITMRR-KGGGAKRL---- YRIVDFK-R--TK-FDVSATVERIEYDPNRTAFIALIKYE-DGEQAYILAPQRLAVGDKVIAGA-K-VD-VKPGNAMPFS GMPIGTIVHNVELKPGKGGQIARSAGTYAQFVGR--DGGYAQIRLSSGELRLVRQECMATIGAVSNSDHSNQNFGKAGRN -RHK-----GIR-P-SVRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGKGTKGTRTR-SNKS-TD-K-YILRSR --------------------------------LRT---G-VIAKKLGMTRLFL-EDGR---------QVPVTVLHVDNVQ VIAQR----TAE----Q--DGY--VALQLGA-------GE--ATTA----------ALRGHFK----------------- ---AN-VAPKRKIAEFRV--------SPENLV-----EV---GE-EIVA--D-H-YFEGQYVDIAGTSIGKGFAGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHLGAVRVTTQNLQVVKTDAERG---------------- ----------LIMVKGS-VPGSKGGWVTIK--MKLDVIT-LDAGKA-GDIDLSDDIF----GL-EP-RADLLHRVVRWQR AKAQAGTHSVLGKSD--------VS-YSTKKIY---------RQKGTGGAR--------HGS---RK-AP----IF---- RHGGVYKGPT-P-RSHAFDLPKKVRALGLKHALSAKAAAG----------------E-LVVVDSL----NIA-E------ --AKTALVI--DGAEN--E---NFARAARNLEGVD-V---------------LPSMGANVYDILRRDT----LVLTRAGV EALEPRLKAQFRETI----RAALKEEFGYKNDMQIPRLDKIVLNMGIG-EAVKDTKKVKQGAEELSLIAGQKAVITKAKK SIAGFRVREEMPLGCKVTLRGDRMYEFLDRLINIALPRVRDFRGVKG-SAFDGRGNYAMGLKEHIVFPEIN-----FDKV DEVLGMDIIICTT-----------------------ARTDAEAKSLLKAFNMPFMSRIG-K--KPVALPKGVTAE-I--- -K-G--Q-TIEVKGPKGTRSFTA--TD-D--VTLAIEE-GA--VKV----T-P--RGLKRAR-QQWGMTRSMVENLTVGV SEGFKKELEIQGVGY--RAQMQG-KT--LKLA--LGYSHDVNFET-P-E-GVTISAP--K-QTEIVVEG-IDQQLVGQVA ANIREWR------RPEPY---KGKGIRYKGEVVFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVKREDGTSIRFDRNAAVILN-NQGE-PVGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--HELHDNPGA-NRKKKRVA-RGPGSGK-GKTAGRGIKGQTSRSGVA----- -LNGY-E-GGQMPLYRRLPK-RG--FSKVNLGQLVTEDALVAA-GVIRVR---------VLA--KGE-I-K-A-A-LNL- SVAGASKAAVEAIEKAGGKI-K---QHK--GRI---HGEA-KGGFNLNFG----------SYALKAI--EPERVTARQIE AARRAITRHM------KRQGRVWIRIFPDVPVSSKPTEVRMGKGK---------GSVDYWAARVHP-GRIMFEI--DG-- VNDTIAREALRLGAQKLPVLTRI-VKRELFQKRRLRVRNKL--RKISDGRPRLSVHRSSKNISVQVIDD---V--KGVTL AAASSL-EKDL-------GVVGK-NNVEAAAKIGAAIAER--AKKAG-VEEVIFDRGGFLFH--GKIKALADAAREGGLK F-------------------------------------------------------------ENE-AFAKTKMLRTSPQK LNLVAAMIRGKKVDKALADLTFS---------------------------------SKRIAGDVKKCLQSAIAN----A- ENNH-NLDVDNLIVAEAWVGKNLVMKRGRPRARGRYGKIMKPFSEITIKVRQAAKLKKGDKVVVLTGK------DK-GKQ GEISAVFPKEN--KAV--VDGINIAIRHQR--------QTQTSQ-GGRVAKAMPIDLSNLA-LLDKN--------GK--A --TRVGFRE----E--------DGKVR---FAKTTG---DVI--MGQKVNPIGMRLQ--VN-RTWDSRWYA------DDK D--YGNLLLEDLKIRDFI--KKEAK-----QAGVSRVVIERPH-K-KCRVTIYAARPGVIIGKKGADIETLRKKLANFLH LNIVEVRK---PELDAQLVAESIAQQLERRVSFRRAMKRAVQNAMRM-GALGIRVNVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYALSEASTPYGIIGVKVWIFMSMNDPLGDMLTRIRNAQMRGKSTVRT-PGSKLRAWVLDVLKAEGYIRGYE EVT---TE---A----GHKELEISLKYY----EG-------T---PVIRELARVSKPGRRVYAGAKELPQVRNGLGVSIV STPKGVMSDAAARSANVGGEVLCTVFMQSQNIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHIDKKSR-DQWEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKVKRILQGKVVSDKNEQTVTVLVERRFKHPLLH KTVRSSKKYRAHDAD--NQFKVGDTVRIVECAPISKTKRWTVLT--ETA------------------------------- -MARSV-WKGPFVDA-YVLRKAEKARE---SGKSD----VIKIWSRRSTILPQFVGLTFGVYNGQKHIPVSVTE-EMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Parvibaculum_lavamentivorans_DS-1 Concatenation of 2 sequences MALKKYKPTSPAQRGLVLVDRSA-LYKG------------KP-VKDLTEGLTKSGGRNNHGRITVRF-RGGGHKRS---- YRTVDFK-R--RR-YDVPATVERLEYDPNRTAFIALVKYE-DGELAYILAPQRLQPGDVVISGS-R-VD-VKPGNAMPLA NIPVGTIVHNVEMKPGKGGQIARSAGTYVQLVGR--DQGYALLRLSSGEQRMVPATCMASIGAVSNPDHSNITIAKAGRN -RWL-----GKR-P-HVRGVVMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKKTR-ANKA-TD-K-YIVRSR --------------------------------MRS---G-VIVKKVGMTRLFM-EDGR---------HVPVTVLKLDNCQ VVSQR----TDE----K--NGY--TAVQLGT-------GR--AVAN----------AQRGQFR----------------- ---AS-VEPKLELVEFRV--------SPDNLL-----DV---GV-EITA--D-H-FIAGQYVDVSGTSIGKGFAGVMKRH NFGG-LRATHGVSVSHRS-HGSTGQN-QDPG-KVFKGKKMAGHMGATRVTTQNLEVVRTDADKG---------------- ----------LIMVKGA-VPGSKGGWVLVR--MKIDVTT-LEAKKA-GSVDLTDGVF----AL-EP-RGDILHRMVAWQL AKRQAGTHKTKGRSE--------IA-LTGKKFV---------KQKGSGGAR--------HGD---RK-AP----QF---- RGGGKAFGPV-V-RSHAFDMPKKVRALALKLALSAKAKSD----------------N-LVILDEA----KLA-E------ --PRTKLII--DGAED--A---NFALAARNLPNVD-V---------------LPVQGINVYDILRREK----LVLTKAAV ESLEPRLKVQYLEKF----RPELTEKFSYKNLLEVPRLDKIVLNMGVG-EAVGDSKKIKSAFEDLQAIAGQKPVITKAKT SIATFKLREGMPIGVKVTLRKDRMYEFLDRLVTVALPRVRDFRGLNA-KSFDGRGNYAMGLKEHIVFPEID-----YDKV DQIWGMDIIVCTT-----------------------AKTDDEARELLRKFNFPFMSRIG-K--YPVEVPKGVTVT-L--- -N-G--Q-DLAVKGPKGELKLTL--VD-D--VTVEQGE-SG--LKV----A-P--REDQRAR-AMWGLSRTLVKNIVTGV TDGFTKTLEINGVGY--RAAIQG-KN--LQLN--LGFSHDVLYPI-P-E-GIDIKCT--K-PTEIVITG-IDKQKVGQVA AEIRGYR------GPEPY---KGKGVKYAGEYIFRKEGK----------MIQQETNLEVADNSGARRVMCIKVLG-SKRK Y--ASVGDIIVVSIKEAIPR-G-------KVKKGDVMKAVVVRTAKDIRRADGSVIRFDRNAAVLIN-NQGE-PIGTRIF GPVTRELR-AKNHMKIVSLAPEVLMK-L--NEIRDNEGA-RKSRIRVG-RGIGSGK-GKTGGRGVKGQKSRTGVA----- -IKGY-E-GGQMPIHMRLPK-RG--FKNVNLGRVVDAAALVAA-GVIRVR---------LLA--QGE-L-K-A-K-LSF- EVAGVSASAKEAVEKAGGSV-K---AHK--GRI---HGKA-KGGMHLDFG----------AFGLKAQ--EPARITARQIE AARRAITRHM------KRAGRVWIRIFPDVPVSSKPTEVRMGKGK---------GAPEYWAARVKP-GRIMFEI--DG-- VPLAVAEEAMRLGAAKLPIKTRF-VMKTLSQRRAMRNRAKL--AKASVVRPRLSVFRSSKHIYAQVIDD---T--RGVTV AAASSL-DEKFGK-------KAG-TDVAAAGEVGKLLAQR--AKDAG-ITDVVFDRGGYIYH--GRVKALAEGAREGGLN F-------------------------------------------------------------ENE-AQAVGRMLRVSPQK LNLVAQLIRGKKVETALADLTFS---------------------------------RKRISDDVKKILQSAIAN----A- ENNH-DLDVDDLIVAEAYVGKNLVMKRWHARARGRVGRIEKPFSQITIVVRQAAKIKKGDKVVILTGK------DK-GKK GDVVAVFPKEN--KAL--VQGVNMVKRHEK----PS--QT--AT-GGIVTREAKVHLSNIA-IQDPKT-------GA--P --TRVGFKT---LD--------DGKVR---FAKASG---ETI--MGHKVNPIGLRLG--IN-RTWDSRWFA------GRH E--YGKLLHEDIKIREVL--EKQLK-----QAGISKIVIERPH-K-KCRVAIHTARPGVVIGKKGADIEKLRREIGKIVH LNIVEVRK---PEIDATLVAENIAQQLERRVAFRRAMKRAVQSAMRL-GAGGIRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGVATAKTAYGTCGVKVWIYMTMTDPLGDMITRIRNAQLRGKGKVVT-PASKLRGWVLDVLAEEGFIRGYA RVE---YP---G----GKSDFEIELKYN----EG-------A---PVIQMIERVSTPGRRVYSSVKTMPTVHNGLGISIL STPKGIMSDVAAREQNVGGEVLCRVFMQRQKIRIRLKGFDHRVLDVSTREIVNTAKRTGAQVLGPIPLPTRLEKFTVLRG PHIDKKSR-EQFEIRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVSDKNEKTIVVNVERRFQDPLLK KIVRRSKKYHAHDEN--KSAKVGDIVKIRECKPVSKLKKWEVFT--DEA------------------------------- -MSRSL-KKGPFVDG-YLLKKAETTRS---SGRKE----VIKMWSRRSTILPQFVGLTFGVHNGKKHVPVLVTE-DMVGH KFGEFSPTRTYFGHT------S---DK----KAK------KG >ALPHA_Phenylobacterium_zucineum_HLK1 Concatenation of 2 sequences MALKQFNPTSPGRRQLVLVDKSE-LHKG------------RP-EKSLVEGLTKSGGRGGNGRISVRF-RGGGAKRL---- YRVIDFK-R--RK-FDVPATVERLEYDPNRSAFIALVKYE-DGELAYILAPQRLKVGDQVIAAE-K-AD-VKPGNAMPLR GMPIGTIIHNVELKPLKGGQIARSAGTYAQLVGR--DAGYAQIRLNSGELRMVQDGCMATVGAVSNPDHMNESLGKAGRS -RHK-----GRR-P-HVRGVAMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGRKTR-KNKA-TD-K-FIIRSR --------------------------------MRT---G-VIAKKLGMARFFD-EAGV---------HVPVTVLSLEGCQ VVAHR----TKD----K--DGY--VALQLGA-------GS--KTSK----------GLRGHF------------------ ---KGQVEPKAKLVEFKV--------SEDNLI-----DV---GA-ELTA--D-H-FVPGQKVDITGTTVGKGFAGAMKRW NFGG-LRATHGVSVSHRS-HGSTGQR-QDPG-RTFPGKKMAGHYGQETVTTLNLTVWRVDAERG---------------- ----------LILVKGA-VPGTEGTFVKIR--MKLDVIK-LDGGKG-GSIELPDDIF----GIEEI-RADILQRCVTWQL AKRRAGTHKIQVRNE--------VS-RTGKKMY---------KQKGTGGAR--------HGS---RR-AA----QF---- VGGAKAHGPV-V-RSHAFDLPKKVRALALRHALSSKAKDG----------------S-LIVLDSA----TLT-E------ --AKTALVI--AGAQD--N---NLKLAARNIPNVD-V---------------LPNAGLNVYDVLRRRT----LVLTKDAV AAIQPRLKTEYRERI----RKSLKDRFGYSNEMQIPKLEKIVINMGVG-EAVADSKKIQSAMADLAKIAGQKPVSTKART SIAGFKLREGMTVGCKVTLRKDRMYEFLDRLITIALPRVKDFRGLKP-TSFDGRGNYAMGLKEHIVFPEIN-----YDQI DQIWGMDIIVTTT-----------------------AKTDDEARELLKEFQFPFMSRIG-K--KAVAVPSGVTVT-I--- -D-G--Q-TVTVKGPKGQLAWTV--AE-E--IEVRQEG-AE--ILL----S-K--RDETRAQ-AMWGLSRTLVNNMVVGV TQGYEQTLELVGVGY--RAAMKG-QA--LSMQ--LGFSHDVDVAP-P-A-GITFATP--K-QTEIKISG-IDKQLVGETA ARIRRLR------PPEPY---KGKGVRYAGENVRRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-AKRR Y--AGVGDKIVVSVKEAIPR-G-------RVKKGDVLQAIVVRTSQGIKRKDGSVIRFDKNAAVIVN-KQSE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLTK-L--NELAPREGS-TKNRMRVG-RGPGSGK-GKTAGRGVKGQKARTGVS----- -IAGF-E-GGQMPLHMRMPK-RG--FNSVNLWRIIDAEALLKA-GVIRVK---------LLG--KGE-L-K-S-K-LNL- TVYSATASARAAVEKAGGKL-K---QFK--GRI---HGTA-KGGFTLNFG----------SYGLKSM--EPERITARQIE AARRAITRQM------KRQGRVWIRVFPDVPVTGKPAEVRMGSGK---------GSVEYWAARVHP-GRIMFEI--DG-- VPDDVAREALRLGAAKLPVKTRI-VPRDTTKRRAQRVRTRL--RKVANGRPRLSVFRSAKNIYAQVIDD---E--RGVTL AAASSL-EGEK-K-------DKG-SDKDAAARVGALVAQR--AIEKG-VKDVVFDRGGYLYH--GRVKALADAAREAGLN F-------------------------------------------------------------GIE-AMAKVRTLRTSPRK LNLVAQSIRGLKVQRALNELEFS---------------------------------HKRIARDVRKALYSAISN----A- ENNH-NLDIDNLVVAEAFVGKNLIMKRFHARARGRASRIEKPFSEITIVVREASKIKKGDRVVVLTGK------DK-GRE GSVLKVFPKEQ--RVL--VEGLNMVQRHTR----PS--QL-DPQ-GGIKNKEAPLHLSNVA-IVD-SK-------GK--P --TRVGFRV----E--------GDKVR---FAKTTG---EVI--MGQKINPVGLRLG--IN-RTWDSRWFA------DGP E--YGRLLHEDIKVRRAL--KKRLY-----QAGVSRIIIERPH-K-KCRITIYAARPGVIIGKKGADIEKLRKDVAAMVH LNIVEIRK---PETDAQLIAENIAQQLERRVAFRRAMKRSMQSAMRL-GAKGVRINVSGRLGGAEIARMEWYREGRVPL- -HTLRADVDYGFTEAKTTYGVIGVKVWVF-MVNDPIGDLIARIKNAASRGRSKLTT-PASKMRARVLDVLAEEGYIRGYQ LVQ----K--PG----AFPEFEIELKYF----DG-------Q---PVIVEISRVSKPGRRVYSSIKDLKPVKNGLGISIL STPKGVMSDNAAREANVGGEVLCRVYMDRQNIRIRLKAFDHRVLDHSTREIVNTAKRTGATVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEIRTHKRVLDIVDPTPQTVDALMKLDLSAGVDVEIKLKRILEGVVVSDKGDKTVVVKVERTFLHPVLK KTVRRSKKYHAHDEA--NTYKVGEVARIIECAPKSKLKTWEVLP--KGG------------------------------- -MTRSV-WKGPFVDG-YLLKKAEAAQS---SGRKD----VIKTWSRRSTIMPQFVGLTFGVHNGHKHVPVLISE-DMVGM KLGEFAPTRFFPGHA------A---DK----KAK------RK >ALPHA_Rhizobium_etli_CFN_42 Concatenation of 2 sequences MALKTFNPTTPSQRQLVIVDRSS-LYKG------------KP-VKALTEGLTKSGGRNNLGRITARF-IGGGHKRS---- YRLVDFK-RR--K-FDIEGTVERIEYDPNRTAFIALVTYS-DGEQAYIIAPQRLAAGDKVIASEKA-VD-VKPGNTMPLQ YIPVGSIIHNVEMKPGKGGQIARSAGSYAQLVGR--DQGMAILRLNSGEQRLVSGVCLASIGAVSNPDHANINDGKAGRT -VWR-----GKR-P-HNRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-MIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HVPVTVLRMDGCQ VVATR----TVE----K--NGY--TAVQLGA-------GQ--ATSK----------AMRGNFV----------------- ---AN-VEPKAKLAEFRV--------SEDNLL-----EI---GT-ELKA--D-H-FAAGQLVDVTGTTIGKGFAGAMKRH GFGG-LRATHGVSVSHRS-HGSTGSR-QDPG-KVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILIKGA-VPGSKGAWIIVR--MELNVKT-LEGKDA-GKVSLSDEIF----GL-EP-REDILARVIRWQL AKKQQGTHKAKGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKKVRALGLRHALSAKIKAD----------------D-VIVIDNL---VAAE-------- --AKTKLFI--GGAED--G---NFKLAAQNIPNID-V---------------LPIQGINVYDIVRRGK----LVLSKAAV EALEPRLKKEYVERI----RKAMQEKFSYANEMMIPKLDKIVINMGVG-EATADSKKPTVAAADLAAIAGQKPVITRARN SIAGFKVRENMPIGAKVTLRGARMYEFLDRLVNIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATTDDEARTLLKEFSFPFMSRIG-K--KPVQVPAGITAT-V--- -E-G--Q-KVTAKGPKGELFFVA--ND-E--ISLKLEN-NA--VVV----T-P-VNQSKDAR-SKWGMSRTMIEGIFKGV KDGYERKLEINGVGY--RAAMQG-KN--LQLA--LGFSHDVVYEP-P-V-GISIAVP--K-PTEIIVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYADERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDVIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGS-THSRKRLG-RGIGSGS-GKTAGRGVKGQKSRSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLARIVDAAALKAA-GVIRVR---------VLA--DGD-L-K-A-K-ITI- VVAGASKPAVEKIEKAGGTV-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEEIAREALRLGSAKLSVKTRF-VRKEALARRANRVRRHI--KSVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTL ASASTL-DKDL-RGSL----KTG-ADTAAAAAVGKLVAER--ASKAG-VTDVVFDRGAFIYH--GRIKALAEAAREGGLT F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVAAAIRGKKVERALAELEFS---------------------------------RKRIAGAVKKTLESAIAN----A- ENNH-DLDVDALVVAEAYVGKSIVMKRFHARGRGRASRIEKPFAHLTIVVREMQKIRKGDKVVMLAGK------DK-GRT GEVVQVMPKED--RAV--VRGVNVVKRHQR----QT--QT--QE-AGIINKEAPVHLSNIA-IVDKD--------GK--P --TRVGFKV----V--------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKMRKFV--MSELK-----QAGISKVVIERPH-K-KCRVTIHSARPGLIIGRKGADIDKLRKKLSDMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGASRRKSSVST-PASKLRARVLDVLQSEGYIRGYS VVD--FGN--------GKSELNIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVGDKNEKTVVVRVERRFAHPLLQ KTVRRSKKYKAHDEN--NEYKIGDTVSIEECAPISKDKRWTVIA--AQG------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRAE----VIKIWSRRSTILPQFVGLTFGVYNGSKHIPVSVNE-DMVGH KFGEFSPTRTYYGHG------A---DK----KAK------RK >ALPHA_Rhizobium_etli_CIAT_652 Concatenation of 2 sequences MALKTFNPTTPSQRQLVIVDRSS-LYKG------------KP-VKALTEGLTKSGGRNNLGRITARF-IGGGHKRS---- YRLVDFK-RR--K-FDVEGTVERIEYDPNRTAFIALVSYA-DGEQAYIIAPQRLAAGDKVIASEKA-VD-VKPGNTMPLQ YIPVGSIIHNVEMKPGKGGQIARSAGSYAQLVGR--DQGMAILRLNSGEQRLVSGICLASIGAVSNPDHANINDGKAGRT -VWR-----GKR-P-HNRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-MIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HVPVTVLRMDGCQ VVATR----TVE----K--NGY--TAVQLGA-------GQ--ATSK----------AMRGNFV----------------- ---AN-VEPKAKLAEFRV--------SEDNLL-----EI---GT-ELKA--G-H-FAAGQLVDVTGTTIGKGFAGAMKRH GFGG-LRATHGVSVSHRS-HGSTGSR-QDPG-KVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILIKGA-VPGSKGAWIIVR--MELNVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDILARVIRWQL AKKQQGTHKAKGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKKVRALGLRHALSAKIKAD----------------D-VIVIDNL---VATE-------- --AKTKLFI--GGAED--G---NFKLAAQNIPNID-V---------------LPIQGINVYDIVRRGK----LVLSKAAV EALEPRLKKEYVERI----RKAMQEKFSYANEMMIPKLDKIVINMGVG-EATADSKKPTVAAADLAAIAGQKPVITRARN SIAGFKVRENMPIGAKVTLRGARMYEFLDRLVNIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATTDDEARALLKEFSFPFMSRIG-K--KPVQVPAGITAT-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--ISLKLED-NA--VVV----T-P-LNQSKNAR-SKWGMSRTMIEGIFKGV KDGFERKLEINGVGY--RAAMQG-KN--LQLA--LGFSHDVVYEP-P-V-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYADERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDVIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGS-THSRKRLG-RGIGSGS-GKTGGRGVKGQKSRSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLARIVDAAALKAA-GVIRVR---------VLA--DGE-L-K-A-K-ITI- VVAGASKPAVEKIEKAGGSV-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEEIAREALRLGSAKLSVKTRF-VRKEALARRANRVRRHI--KSVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTL ASASTL-EKDL-RGSL----KTG-ADTAAAAAVGKLVAER--ASKAG-VSEVVFDRGAFIYH--GRIKALAEAAREGGLT F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVAAAIRGKKVERALAELEFS---------------------------------RKRIAGAVKKTLESAIAN----A- ENNH-DLDVDALVVAEAYVGKSIVMKRFHARGRGRASRIEKPFAHLTIVVREMQKIRKGDKVVMLAGK------DK-GRT GEVVQVMPKED--RAV--VRGVNVVKRHQR----QT--QT--QE-AGIINKEAPVHLSNIA-IVDKD--------GK--P --TRVGFKV----V--------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKMRKFV--MSELK-----QAGISKVVIERPH-K-KCRVTIHSARPGLIIGRKGADIDKLRKKLSDMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGASRRKSSVST-PASKLRARVLDVLQSEGYIRGYS VVD--FGN--------GKSELNIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVGDKNEKTVVVRVERRFAHPLLQ KTVRRSKKYKAHDEN--NQYKIGDTVSIEECAPISKDKRWTVIA--AQG------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRAE----VIKIWSRRSTILPQFVGLTFGVYNGSKHIPVSVNE-DMVGH KFGEFSPTRTYYGHG------A---DK----KAK------RK >ALPHA_Rhizobium_leguminosarum_bv_trifolii_WSM2304 Concatenation of 2 sequences MALKTFNPITPSQRQLVIVDRSA-LYKG------------KP-VKALTEGLTKSGGRNNLGRITARF-IGGGHKRT---- YRLIDFK-RR--K-FDVEGTVERIEYDPNRTAFIALVNYA-DGEKAYILAPQRLAAGDKVIASEKA-VD-VKPGNTMPLQ FIPVGSIIHNVEMKPGKGGQIARSAGGYAQLVGR--DQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHANINDGKAGRT -VWR-----GKR-P-HNRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-MIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HVPVTVLRMDGCQ VVATR----TVE----K--NGY--TAVQLGA-------GQ--ATSK----------AMRGNFV----------------- ---AN-VEPKAKVAEFRV--------SEDQLL-----EI---GT-EIKA--G-H-FAAGQLVDVTGTTIGKGFAGAMKRH GFGG-LRATHGVSVSHRS-HGSTGSR-QDPG-KVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILIKGA-VPGSKGAWIIVR--MEFNVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDILARVIRWQL AKKQQGTHKAKGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKKVRALGLRLALSAKIKAD----------------D-VIVIDNL---VAAE-------- --AKTKLFI--GGAED--G---NFKLAAQNIPNID-V---------------LPIQGINVYDIVRRGK----LVLSKAAV EALEPRLKKEYVERI----RKAMQEQFSYANEMMIPKLDKIVINMGVG-EATADSKKPTVAAADLAAIAGQKPVITRARN SIAGFKVREQMPIGAKVTLRGARMYEFLDRLVNIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFLEIN-----YDKV DQMWGMDIIVCTT-----------------------ATTDDEARALLKEFSFPFMSRIG-K--KPVQVPAGITAT-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--ISLKLEN-NA--VVV----T-P-VNQTKDAR-SKWGMSRTMIEGIFKGV KDGFERKLEINGVGY--RASLQG-KN--LQLA--LGFSHDVLYEP-P-V-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYADERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDVIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGS-THSRKRLG-RGIGSGS-GKTGGRGVKGQKSRSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLARIVDAAALKAA-GVIRVR---------VLA--DGE-L-K-A-K-ITI- VVAGASKPAVEKIEKAGGTV-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTKKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEEIAREALRLGSAKLSVKTRF-VRKEALARRANRVRRHL--KSVANGRPRLSVHRSSKNIYAQVIDD---V--AGKTL AAASTL-DKDL-RGSL----KTG-ADTAAAALVGKLVAER--ASKAG-VTDVVFDRGAFIYH--GRIKALADAAREGGLT F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVAAAIRGKKVERALAELEFS---------------------------------RKRIAGAVKKTLESAIAN----A- ENNH-DLDVDALVVAEAYVGKSIVMKRFHARGRGRASRIEKPFAHLTIVVREMQKIRKGDKVVMLAGK------DK-GRT GEVVQVMPKED--RAV--VRGVNVVKRHQR----QT--QT--QE-AGIINKEASVHLSNVA-IVDKD--------GK--P --TRVGFKV----V--------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKMRKFV--MSELK-----QAGISKVVIERPH-K-KCRVTIHSARPGLIIGRKGADIDKLRKKLSDMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGASRRKSSVST-PASKLRARVLDVLQSEGYIRGYS VVD--FGN--------GKSELSIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVGDKNEKTVVVRVERRFAHPLLQ KTVRRSKKYKAHDEN--NQYKIGDTVSIEECAPISKDKRWTVIS--AQG------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRAE----VIKIWSRRSTILPQFVGLTFGVYNGSKHIPVSVNE-DMVGH KFGEFSPTRTYYGHG------A---DK----KAK------RK >ALPHA_Rhizobium_leguminosarum_bv_viciae_3841 Concatenation of 2 sequences MALKTFNPITPSQRQLVIVDRSA-LYKG------------KP-VKALTEGLTKSGGRNNLGRITARF-IGGGHKRT---- YRLIDFK-RR--K-FDVEGTVERIEYDPNRTAFIALVNYA-DGEKAYILAPQRLAAGDKVIASEKA-VD-VKPGNTMPLQ FIPVGSIIHNVEMKPGKGGQIARSAGGYAQLVGR--DQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHANINDGKAGRT -VWR-----GKR-P-HNRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-MIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HVPVTVLRMEGCQ VVATR----TVE----K--NGY--TAVQLGA-------GQ--ATSK----------AMRGNFI----------------- ---AN-VEPKAKLTEFRV--------SEDQLL-----EV---GT-EIKA--G-H-FAAGQLVDVTGTTIGKGFAGAMKRH GFGG-LRATHGVSVSHRS-HGSTGSR-QDPG-KVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILIKGA-VPGSKGAWIIVR--MEFNVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDILARVIRWQL AKKQQGTHKAKGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHEHDLPKKVRALGLRHALSAKIKAD----------------D-VIVIDNL---VAAE-------- --AKTKLFI--GGAED--G---NFKLAAQNIPNID-V---------------LPIQGINVYDIVRRGK----LVLSKAAV EALEPRLKKEYVERI----RKALQEQFSYANEMMIPKLDKIVINMGVG-EATADSKKPTVAAADLAAIAGQKPVITRARN SIAGFKVREQMPIGAKVTLRGARMYEFMDRLVNIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATTDDEARALLKEFSFPFMSRIG-K--KPVQVPAGITAT-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--ISLKLEN-NA--VVV----T-P-VNQTKDAR-SKWGMSRTMIEGIFKGV KDGFERKLEINGVGY--RAAMQG-KN--LQLA--LGFSHDVIYEP-P-V-GISIVVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYADERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDVIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGS-THSRKRLG-RGIGSGS-GKTGGRGVKGQKSRSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLARIVDAAALKAA-GVIRVR---------VLA--DGE-I-K-A-K-ITI- VVAGASKPAVEKIEKAGGTV-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRYM------KRAGRVWIRVFPDVPVTKKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEEIAREALRLGSAKLSVKTRF-VRKEALARRANRVRRHL--KSVANGRPRLSVHRSSKNIYAQVIDD---V--AGKTL ASASTL-EKDL-RGSL----KTG-ADTAAATVVGKLLAER--ASKAG-VTEVVFDRGAFIYH--GRIKALAEAAREGGLT F-------------------------------------------------------------DNE-AQAVARTLRVSPQK LNLVAAAIRGKKVERALAELEFS---------------------------------RKRIAGAVKKTLESAIAN----A- ENNH-DLDVDSLVVAEAYVGKSIVMKRFHARGRGRASRIEKPFAHLTIVVREMQKIRKGDKVVMLAGK------DK-GRT GEVVQVMPKED--RAV--VRGVNVVKRHQR----QT--QT--QE-AGIINKEAPVHLSNVA-IIDKD--------GK--P --TRVGFKV----V--------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKMRKFV--MSELK-----QAGISKVVIERPH-K-KCRVTIHSARPGLIIGRKGADIDKLRKKLSEMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGIKVWIFMTMTDPLGDMLTRIRNGASRRKSSVST-PASKLRARVLDVLQSEGYIRGYS VVD--FGN--------GKSELSIELKYY----EG-------A---SVIREIGRVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVVGDKNEKTVVVRVERRFAHPLLQ KTVRRSKKYKAHDEN--NQYKIGDTVSIEECAPISKDKRWTVIS--AQG------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRSE----VIKIWSRRSTILPQFVGLTFGVYNGSKHIPVSVNE-DMVGH KFGEFSPTRTYYGHG------A---DK----KAK------RK >ALPHA_Rhizobium_sp_NGR234_(ANU265) Concatenation of 2 sequences MALKSFNPTTPSQRQLVIVDRAG-LYKG------------KP-VKTLTEGLSSKGGRNNLGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEGTVERLEYDPNRTAFIALVNYA-DGEQAYILAPQRLAAGDKVIASDKA-VD-VKPGNTMPLQ FIPVGSIIHNVEMKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHGNINDGKAGRS -RWR-----GKR-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-FIMRSR ---------------------------MEFLQMRS---G-VIAQKVGMTRVYN-DAGE---------HIPVTVLRLENCQ VVAQR----TEE----K--NGY--TAVQLGA-------GR--STTK----------ALRGHF------------------ ---AASVEPKAKVVEFRV--------TADNLI-----DI---GA-ELTA--S-H-FVAGQLVDVTGTTIGKGFAGAIKRH NFGG-LRATHGVSVSHRS-HGSTGSN-QDPG-RVWKGKRMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGAWIVVR--MDLTVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDIIARVVRWQL AKRQQGTHKAKGRAE--------VA-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHDLPKKVRALGLRHALSAKLKAE----------------E-IIVLDDL----VAN-E------ --AKTKLII--GGAEE--N---NFKLAAQNIPNVD-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRLKKEYVERI----RKAMQEKFSYANEMQIPRLDKIVINMGVG-EATGDSKKPSVAAADLAAIAGQKPVITRARN SIAGFKLREGMPIGAKVTLRGVRMYEFLDRLVNIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATNDDEARALLAEFNFPFMSRIG-K--KPVQVPAGVTAS-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--VSVKLEN-NA--VVV----Q-P-LNESKDAR-AKWGMSRTMVENIFKGV KDGYERKLEINGVGY--RASMQG-KN--LQLA--LGFSHDVVYQT-P-E-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAGERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGA-TKSRKRLG-RGIGSGS-GKTAGRGVKGQKARSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLGRIVDAAALKAA-GVIRVR---------VLA--DGE-L-K-A-K-ISL- EVAGASKPAVEKIEKAGGSI-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRHM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VNEELAREALRLGAAKLSVKTRF-VRKDTLVRRASRVRRQI--KAVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTI AAASTL-EADL-KSAL----KTG-ADTAAATAVGKLLAER--ASKAG-VKDVVFDRGAFIYH--GRVKALAEAAREGGLN F-------------------------------------------------------------DNE-AQAIARTIRVSPQK LNLVAALIRGKKVDRALAELEFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDSLIVAEAYVGKSIVMKRFHARGRGRASRVEKPFSHLTIVVREMQKIRKGDKVVVLTGK------DK-GRT GEVIQVMPKED--RAV--VRGVNVVKRHQR----QTQNQE-----AGIISKEAPIHLSNIA-IADPKD-------GK--P --TRVGFKI-------------DGKVR---VAKRSG---EVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKIRAYL--MEELK-----AAGIAKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRKKLSEMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGVKVWIFMAMTDPLGDMLTRIRNGAARRKSSVST-PASKLRARVLDVLQAEGYIRGYS EVE--FGN--------GKAELNIELKYY----EG-------A---SVIREIARVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGELLCSVFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGTVVSDKNDKTVVVKVERRFAHPILQ KTVRRSKKYKAHDEN--NQYKVGDVVSIEECAPISKDKRWTVIA--AQA------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Rhodobacter_sphaeroides_241 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKTLVEGLIKTGGRNNTGRVTMWH-KGGGAKRL---- YRIVDFK-RR--K-FDVPAVVERIEYDPNRTAFIALVRYE-DGELAYILAPQRLAVGDSVVAGV-K-TD-VKPGNAMPFS GMPIGTIVHNVELKPGKGGQLARAAGTYAQFVGR--DGGYAQIRLSSGELRMVRQECMATVGAVSNPDNSNQNFGKAGRM -RHK-----GVR-P-TVRGVAMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKGTKGNRTR-K-SKASD-K-LIVRSR --------------------------------MRS---G-VIAKKLGMTRLFL-EDGK---------QVPVTVLQLDSLQ VVAQR----TTE----K--DGY--TAVQLGA-------GA--AVSA----------AQRGHFK----------------- ---AN-VEPKRKIAEFRV--------TPDCLI-----DV---GA-EITA--D-H-YFAGQFVDIAGTSIGKGFAGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHMGAARVTTQNLQVVRTDSDRG---------------- ----------LIMVKGA-VPGSKGGWVTIK--MKAEVIK-LDASPA-GSIELDDAIF----GL-EP-RADILHRVVRWQR AKAQAGTHSVLGKSD--------VS-YSTKKIY---------RQKGTGGAR--------HGS---KK-AP----IF---- RHGGVYKGPT-P-RSHAHDLNKKFRALGLKHALSSKATTG----------------N-LIVLEDI----ALA-E------ --GKTALVI--DGADN--E---NFAKAARNLEGVD-V---------------LPSIGANVYDILKRDT----LVITKAGV EALEPRLKAAYANSV----RAAMKEEFGYKNDMQIPRLDKIVLNMGVG-EAVKDTKKVKTAAEELSMIAGQKAVVTHAKK SIAGFRVREQMPLGCKVTLRGDRMYEFLDRLITIALPRVRDFRGVKG-NSFDGRGNYAMGLKEQFVFPEIN-----FDKV DEVLGMDIIICTT-----------------------AKTDAEAKALLKQFNMPFMSRIG-K--KPVPLPKGVTAS-I--- -S-G--Q-SIEVKGPKGTRSFSA--TD-D--VTLALDE-GS--VKV----T-P--RGTKRAR-QQWGMVRSQVENLVTGV TSGFKKELEISGVGY--RAQMAG-NV--LKLS--LGYSHDVNFEV-P-A-GVTVTTP--K-QTEITVEG-IDQQLVGQVA ANIREWR------RPEPY---KGKGIRYKDEFIFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTTIRFDRNAAVILN-NQGE-PVGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--NELRDNEGA-ARKKKRVA-RGPGSGK-GKTAGRGIKGQKSRSGVA----- -LNGY-E-GGQMPLYRRLPK-RG--FTKVNLGLIIDENAIVAA-GVTSIR---------VLA--KGE-I-T-A-K-LAL- TVSGASKSAVEAIEKAGGSI-K---QHK--GRI---HGEA-KGGFLLNFG----------GFGLKAT--EPERVTARQIE AARRAITRHM------KRQGRVWIRVFPDVPVTSKPTEVRMGKGK---------GSVDYWAAKVKP-GRIMFEI--DG-- VSETIAREALRLGAMKLPVMTRI-VKRELFLKRRLRVRNKL--KASANGRLRLSVHRSSKNISAQLIDD---A--NGVTL AAASTL-EKGL-------GFVGK-NNVEASAAVGRAIAER--AKAAG-IEECFFDRGGFLFH--GKIKALADAAREGGLK F-------------------------------------------------------------ENE-AFAKVKMLRTSPQK LNLVAALIRGKKVDKAIADLTFS---------------------------------KKRISQDVLKCLQSAIAN----A- ENNH-GLDVDELVVSEAFCGKNLVMKRGRPRARGRFGKIMKPFSELTIKVKQAAKLKKGDRVVVLAGK------DK-GKQ GEITAVMPKDN--KAV--VEGVNVAIRHTK--------QTPTAQ-GGRLAKAMPIDLSNLA-LLDAN--------GK--A --TRVGFRF----E--------GEKVR---YAKTTG---DVI--MGQKVNPIGMRLQ--VN-RTWDSRWFA------ESK D--YGNLLLEDLKMREFI--HDYAK-----QAGVSKVIIERPH-R-KCRVTIHTARPGVIIGKKGADIETLRKKLSAFLH LNIVEIRK---PELDAQLVAESIAQQMERRVSFRRAMKRGVQNAMRI-GALGIRVNVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSEATTPYGIIGVKVWIFMSVNDPLGDMLTRIRNAQLRGKSTVST-PASRLRAWVLDVLQAEGYIRGYE KKE---TE---N----GQGELVISLKYF----EG-------T---PVIRELKRVSKPGRRVYMATKDLPSVRNGLGVSII STPKGVMSDASARSANVGGEVLCTVFMQGQTIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHIDKKSR-DQWEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDIQIKVKRILQGTVTSDKNEQTVTVLVERRFKHPLLK KTVRLSKKYRAHDPE--NQFKVGDIVRIEECAPISKTKRWKVVT--DAV------------------------------- -MARST-WKGPFVDG-YLLKKAEKSRE---SGKNE----VIKIWSRRSTILPQFVGLTFGVYNGKKHVPVNVTE-EMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Rhodobacter_sphaeroides_ATCC_17029 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKTLVEGLIKTGGRNNTGRVTMWH-KGGGAKRL---- YRIVDFK-RR--K-FDVPAVVERIEYDPNRTAFIALVRYE-DGELAYILAPQRLAVGDSVVAGV-K-TD-VKPGNAMPFS GMPIGTIVHNVELKPGKGGQLARAAGTYAQFVGR--DGGYAQIRLSSGELRMVRQECMATVGAVSNPDNSNQNFGKAGRM -RHK-----GVR-P-TVRGVAMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKGTKGNRTR-K-SKASD-K-LIVRSR --------------------------------MRS---G-VIAKKLGMTRLFL-EDGK---------QVPVTVLQLDSLQ VVAQR----TTE----K--DGY--TAVQLGA-------GA--AVSA----------AQRGHFK----------------- ---AN-VEPKRKIAEFRV--------TPDCLI-----DV---GA-EITA--D-H-YFAGQFVDIAGTSIGKGFAGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHMGAARVTTQNLQVVRTDSDRG---------------- ----------LIMVKGA-VPGSKGGWVTIK--MKAEVIK-LDASPA-GSIELDDAIF----GL-EP-RADILHRVVRWQR AKAQAGTHSVLGKSD--------VS-YSTKKIY---------RQKGTGGAR--------HGS---KK-AP----IF---- RHGGVYKGPT-P-RSHAHDLNKKFRALGLKHALSSKATTG----------------N-LIVLEDI----ALA-E------ --GKTALVI--DGADN--E---NFAKAARNLEGVD-V---------------LPSIGANVYDILKRDT----LVITKAGV EALEPRLKAAYANTV----RAAMKEEFGYKNDMQIPRLDKIVLNMGVG-EAVKDTKKVKTAAEELSMIAGQKAVVTHAKK SIAGFRVREQMPLGCKVTLRGDRMYEFLDRLITIALPRVRDFRGVKG-NSFDGRGNYAMGLKEQFVFPEIN-----FDKV DEVLGMDIIICTT-----------------------AKTDAEAKALLKQFNMPFMSRIG-K--KPVPLPKGVTAS-I--- -S-G--Q-SIEVKGPKGTRSFSA--TD-D--VTLALDE-GS--VKV----T-P--RGTKRAR-QQWGMVRSQVENLVTGV TSGFKKELEISGVGY--RAQMAG-NV--LKLS--LGYSHDVNFEV-P-A-GVTVTTP--K-QTEITVEG-IDQQLVGQVA ANIREWR------RPEPY---KGKGIRYKDEFIFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTTIRFDRNAAVILN-NQGE-PVGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--NELRDNEGA-ARKKKRVA-RGPGSGK-GKTAGRGIKGQKSRSGVA----- -LNGY-E-GGQMPLYRRLPK-RG--FTKVNLGLIIDENAIVAA-GVTSIR---------VLA--KGE-I-T-A-K-LAL- TVSGASKSAVEAIEKAGGSI-K---QHK--GRI---HGEA-KGGFLLNFG----------GFGLKAT--EPERVTARQIE AARRAITRHM------KRQGRVWIRVFPDVPVTSKPTEVRMGKGK---------GSVDYWAAKVKP-GRIMFEI--DG-- VSETIAREALRLGAMKLPVMTRI-VKRELFLKRRLRVRNKL--KASANGRLRLSVHRSSKNISAQLIDD---A--NGVTL AAASTL-EKGL-------GFVGK-NNVEASAAVGRAIAER--AKAAG-IEECFFDRGGFLFH--GKIKALADAAREGGLK F-------------------------------------------------------------ENE-AFAKVKMLRTSPQK LNLVAALIRGKKVDKAIADLTFS---------------------------------KKRISQDVLKCLQSAIAN----A- ENNH-GLDVDELVVSEAFCGKNLVMKRGRPRARGRFGKIMKPFSELTIKVKQAAKLKKGDRVVVLAGK------DK-GKQ GEITAVMPKDN--KAV--VEGVNVAIRHTK--------QTPTAQ-GGRLAKAMPIDLSNLA-LLDAN--------GK--A --TRVGFRF----E--------GEKVR---YAKTTG---DVI--MGQKVNPIGMRLQ--VN-RTWDSRWFA------ESK D--YGNLLLEDLKMREFI--HDYAK-----QAGVSKVIIERPH-R-KCRVTIHTARPGVIIGKKGADIETLRKKLSAFLH LNIVEIRK---PELDAQLVAESIAQQMERRVSFRRAMKRGVQNAMRI-GALGIRVNVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSEATTPYGIIGVKVWIFMSVNDPLGDMLTRIRNAQLRGKSTVST-PASRLRAWVLDVLQAEGYIRGYE KKE---TE---N----GQGELVISLKYF----EG-------T---PVIRELKRVSKPGRRVYMATKDLPSVRNGLGVSII STPKGVMSDASARSANVGGEVLCTVFMQGQTIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHIDKKSR-DQWEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDIQIKVKRILQGTVTSDKNEQTVTVLVERRFKHPLLK KTVRLSKKYRAHDPE--NQFKVGDIVRIEECAPISKTKRWKVVT--DAV------------------------------- -MARST-WKGPFVDG-YLLKKAEKSRE---SGKNE----VIKIWSRRSTILPQFVGLTFGVYNGKKHVPVNVTE-EMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Rhodopseudomonas_palustris_CGA009 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-VKRLTEGKNSNGGRNNTGRITVRF-RGGGHKQA---- YRLVDFK-RT--K-VDVPAKVERLEYDPNRTAFIALIKYE-DGEQAYILAPQRLAVGDTVIAGA-Y-VD-VKPGNVMPLG NMPIGTIVHNVELKIGKGGQLARSAGTYAQIVGR--DHDYVILRMNSGEQRLIHGRCIAAIGAVSNPDHMNISIGKAGRK -RWL-----GRR-P-HNRGVVMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-S-NKSTD-K-FILISR --------------------------------MRS---G-VIAQKVGMTRVFT-EAGE---------HIPVTVLKLGNCQ VLGHR----TKE----K--NGY--VALQVGS-------GS--RMPK----------AERGQF------------------ ---AAKVEPKRKVEEFRV--------SEDALL-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSTGKGFAGGMKRW NFGG-LRATHGVSVSHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGVDRVTTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGTKGGWIRVR--MELKVTT-LEGKEA-GSVQLSDEIF----GL-EP-RSDIIQRCVIWQL AKRQAGTHKAKGRAE--------VW-RTGKKMY---------KQKGTGGAR--------HGS---QR-VP----QF---- RGGGRAFGPV-V-RSHAIDLPKKVRVLALRHALSAKAKGG----------------G-LIVLDKA----ELE-A------ --AKTKLII--DGAEN--N---GFAAAARNIPNID-V---------------LPVQGINVYDILRRKK----LVLTKAAV DALEPRLRTEYDRHI----RTQLTEKFGYANVMQVPKLDKVVLNMGVG-EAVNDRKKAEQAAADLSLIAGQKAVITYSRV AISTFKLRENQPIGCKVTLRQARMYEFIDRLITVALPRVRDFRGLNP-KSFDGRGNYSLGIKEHIIFPEID-----FDKT GESWGMDITVCTT-----------------------ARTDDEARALLTAFNFPFMSRVG-K--KPVTVPSGVTAT-V--- -E-G--Q-TVKMKGPKGQLQFVV--HD-D--VDVKFED-GA--VKV----A-P-RHETNRAR-ALYGTARAQIANLVEGV TKGFEKKLEITGVGY--RAAMQG-KK--LQLA--LGYSHDVLYDI-P-E-GITITVP--K-PTEINVVG-IDPQKVGQVA AEIRDYR------PPEPY---KGKGVRYADEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVIG-SKRR Y--ATVGDVIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLIN-NQSE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SEIADNVGS-RKKRMRIG-RGIGSGK-GKTGGRGGKGQTARSGVR----- -IKGF-E-GGQMPLHRRLPK-RG--FNNVNLDRLVDAAALVEA-GVLRVR---------LLG--RGE-L-T-A-K-LNI- EVHGATKSAIAAVEKAGGSV-K---AHK--GRI---HGVA-SSGATLAFG----------QFGLKAM--EPERITARQIE AARRALTRHM------KRAGRVWIRVFPDLPVSKKPAEVRMGSGK---------GSPELWVARVKP-GRVMFEI--DG-- VNQQIAREALTLAAAKLPIKTRF-VMKITNARRTNRVRTAL--RRTANGRPRLSVFRSSKHIYAQVIDD---A--KGETL ASASSL-EKTM-RDAG----NTG-ANIDAAKAVGKLVAER--AVEKG-VKEVVFDRGGYLYH--GRVKALADAARESGLS F-------------------------------------------------------------DNE-AKAVARMLRVSPQK LNLVAQLIRGRKASAALADLAFS---------------------------------RKRIAVDVKKCLESAIAN----A- ENNH-DLDVDALVVSEAHVGKGIVMKRFTPRGRGRSGRIFKPFAQLTIVVRQAAKIRKGDKVIVLSGR------DK-GRT GEVFEVRPDAG--KAL--VRGINVVKRHQK----QT--QT-Q-E-GGIISKEAPIDLSNIA-IVG-KD-------GK--P --TRVGFKI---LA--------DGKVR---VAKRSG---AEI--MGQKINPIGLRLG--IN-RTWDSRWFA------GKN E--YGKLLHEDVKIREIL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKKVADIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRSKSKVST-PGSKMRANVLDVLKAEGYIRGYA TVE--HPS--------GRSELEIELKYF----DG-------E---PVIREIERVSRPGRRVYASVKNLPRVNNGLGISVL STPKGIMADHDARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQAKTIVVRVDRRFTHPIYK KTIRRSKNYHAHDEN--NQFKPGDMVWIEESKPISKLKRWTVVR--KKT------------------------------- -MVRSV-WKGPFVEA-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLTFGVYNGQKHVPVSVNE-EMVGH KFGEFSPTRTFHGHA------G---DK----KSK------KG >ALPHA_Rhodopseudomonas_palustris_TIE-1 Concatenation of 2 sequences MALKTFNPTTPGQRQLVMVDRSA-LYKG------------KP-VKRLTEGKNSNGGRNNTGRITVRF-RGGGHKQA---- YRLVDFK-RT--K-VDVPAKVERLEYDPNRTAFIALIKYE-DGEQAYILAPQRLAVGDTVIAGA-Y-VD-VKPGNVMPLG NMPIGTIVHNVELKIGKGGQLARSAGTYAQIVGR--DHDYVILRMNSGEQRLIHGRCIAAIGAVSNPDHMNISIGKAGRK -RWL-----GRR-P-HNRGVVMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-S-NKSTD-K-FILISR --------------------------------MRS---G-VIAQKVGMTRVFT-EAGE---------HIPVTVLKLGNCQ VLGHR----TKE----K--NGY--VALQVGS-------GS--RMPK----------AERGQFA----------------- ---AK-VEPKRKVEEFRV--------SEDALL-----PV---GA-EIQA--D-H-FVVGQFVDVTGTSTGKGFAGGMKRW NFGG-LRATHGVSVSHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGVDRVTTLNLRVVQTDVERG---------------- ----------LILVEGA-VPGTKGGWIRVR--MELKVTT-LEGKEA-GSVQLSDEIF----GL-EP-RSDIIQRCVIWQL AKRQAGTHKAKGRAE--------VW-RTGKKMY---------KQKGTGGAR--------HGS---QR-VP----QF---- RGGGRAFGPV-V-RSHAIDLPKKVRVLALRHALSAKAKGG----------------G-LIVLDKA----ELE-A------ --AKTKLII--DGAEN--N---GFAAAARNIPNID-V---------------LPVQGINVYDILRRKK----LVLTKAAV DALEPRLRTEYDRHI----RTQLTEKFGYANVMQVPKLDKVVLNMGVG-EAVNDRKKAEQAAADLSLIAGQKAVITYSRV AISTFKLRENQPIGCKVTLRQARMYEFIDRLITVALPRVRDFRGLNP-KSFDGRGNYSLGIKEHIIFPEID-----FDKT GESWGMDITVCTT-----------------------ARTDDEARALLTAFNFPFMSRVG-K--KPVTVPSGVTAT-V--- -E-G--Q-TVKMKGPKGQLQFVV--HD-D--VDVKFED-GA--VKV----A-P-RHETNRAR-ALYGTARAQIANLVEGV TKGFEKKLEITGVGY--RAAMQG-KK--LQLA--LGYSHDVLYDI-P-E-GITITVP--K-PTEINVVG-IDPQKVGQVA AEIRDYR------PPEPY---KGKGVRYADEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVIG-SKRR Y--ATVGDVIVVSIKEAIPR-G-------KVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLIN-NQSE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--SEIADNVGS-RKKRMRIG-RGIGSGK-GKTGGRGGKGQTARSGVR----- -IKGF-E-GGQMPLHRRLPK-RG--FNNVNLDRLVDAAALVEA-GVLRVR---------LLG--RGE-L-T-A-K-LNI- EVHGATKSAIAAVEKAGGSV-K---AHK--GRI---HGVA-SSGATLAFG----------QFGLKAM--EPERITARQIE AARRALTRHM------KRAGRVWIRVFPDLPVSKKPAEVRMGSGK---------GSPELWVARVKP-GRVMFEI--DG-- VNQQIAREALTLAAAKLPIKTRF-VMKITNARRTNRVRTAL--RRTANGRPRLSVFRSSKHIYAQVIDD---A--KGETL ASASSL-EKTM-RDAG----NTG-ANIDAAKAVGKLVAER--AVEKG-VKEVVFDRGGYLYH--GRVKALADAARESGLS F-------------------------------------------------------------DNE-AKAVARMLRVSPQK LNLVAQLIRGRKASAALADLAFS---------------------------------RKRIAVDVKKCLESAIAN----A- ENNH-DLDVDALVVSEAHVGKGIVMKRFTPRGRGRSGRIFKPFAQLTIVVRQAAKIRKGDKVIVLSGR------DK-GRT GEVFEVRPDAG--KAL--VRGINVVKRHQK----QT--QT-Q-E-GGIISKEAPIDLSNIA-IVG-KD-------GK--P --TRVGFKI---LA--------DGKVR---VAKRSG---AEI--MGQKINPIGLRLG--IN-RTWDSRWFA------GKN E--YGKLLHEDVKIREIL--HKELK-----QAAVARIVIERPH-K-KCRVTIHSARPGVVIGKKGADIDKLRKKVADIVV INIVEIRK---PELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARMEWYREGRVPL- -HTLRADIDYGVATAFTTFGTCGVKVWIFMSTHDPISDLITRIRNAQMRSKSKVST-PGSKMRANVLDVLKAEGYIRGYA TVE--HPS--------GRSELEIELKYF----DG-------E---PVIREIERVSRPGRRVYASVKNLPRVNNGLGISVL STPKGIMADHDARDANVGGEVLFTVFMNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRTLQGVVVSDKQAKTIVVRVDRRFTHPIYK KTIRRSKNYHAHDEN--NQFKPGDMVWIEESKPISKLKRWTVVR--KKT------------------------------- -MVRSV-WKGPFVEA-SLLKKADAARA---SGRHD----VIKIWSRRSTILPQFVGLTFGVYNGQKHVPVSVNE-EMVGH KFGEFSPTRTFHGHA------G---DK----KSK------KG >ALPHA_Rhodospirillum_centenum_SW Concatenation of 2 sequences MALKTFRPITPSLRQLVLVDRSE-LWKG------------KP-VKALTEGLTGSGGRNNTGRITARR-MGGGHKRR---- YRLVDFK-RR-MK-PDMPATVERLEYDPNRTAFIALIRYT-DGTLAYILAPQRLKAGDTVVSGE-K-VD-VKPGNAMPLR NIPVGTIVHNVELKPGKGGQLARAAGTYLQLVGR--DQGYAQLKLPSGELRVVRGECFATIGAVSNPDQANVVIGKAGRN -RWL-----GRR-P-SVRGVVMNPIDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKKTR-Q-NKATD-K-FIIRRR --------------------------------MRS---G-LIAQKLGMTRVFT-DEGE---------HVPVTVLKLDQVQ VVAQR----TED----R--DGY--TALQLGA-------GK--AVAK----------AQREQFR----------------- ---AK-VEPKKKLVEFRV--------TPDALI-----EV---GA-EITA--D-H-FVPGQFVDVTGTTIGRGFTGPMRRW NFGG-LRATHGVSVSHRS-HGSTGGR-QDPG-KTFKNKKMAGHYGVEKVTVQNLKVVQVDVERG---------------- ----------LILVKGA-IPGHEGGWVLIR--MKTTVKN-LNNETV-GEIELADEVF----GL-PT-RQDILTRMVLWQL AKRRQGTHKTKGISE--------IA-GTTKKPW---------RQKGTGRAR--------QGS---TR-SP----QF---- RGGARIFGPV-V-RSHEHDLTKKVRKLALKTALSTKAAEG----------------K-LFVLEAA----KAD-T------ --HKTKLII--DGAND--E---TFVRAARNIPHLD-V---------------LPEQGANVYDILRRDV----LVLTRNAV EQLEARLKERYDTVV----RPSLKAEFNYANDMEVPRIEKIVINMGVG-EAAGDGKKIQSAVADLTAITGQKPVVTRARK SIAQFKLRENMPIGCKVTLRRDRMYEFLDRLVTIALPRVRDFRGIPG-NSFDGRGNYAMGLKEQLIFPEID-----YDKV DEVRGMDIIIVTT-----------------------AKTDKEAKALLKGFDMPFMSRIG-K--HPVPVPAGVTVT-V--- -A-G--Q-NLTAKGKLGQLSLSL--ID-D--IAVSMED-GK--VVV----Q-P--RTEKRAR-QNWATARTLVFNLVKGV NDGFTKNLEINGVGY--KAAVQG-KD--LVLN--LGYSHEIRYPI-P-E-GITIKCD--K-PTSVSVSG-TDKQQVGQVA AEIRAFR------GPEPY---KGKGVKYENEVIIRKEGK----------MIQMQTNLEVADNSGARRVQCIKVLG-AGRR F--ASVGDIIVVSVKEAIPR-G-------RVKKGDVHRAVIVRTAKEIRREDGSCIRFDRNAAVLIN-KQGE-PIGTRIF GPVTRELR-AKKYMKIISLAPEVLMK-L--NELKDNPGA-RKERMRVG-RGIGSGK-GKTGGRGVKGQKSRTGVS----- -IKGF-E-GGQMPLHRRLPK-RG--FRNVNLGKIVTVDVLRAA-GLVKVR---------LLA--KGT-L-T-A-A-VTF- EVAGASAAAVEAVEKAGGKV-K---AHK--GRI---HGTA-KGGTSLNFG----------AYGLKAV--EPMRVTARQIE SARRAITRHL------KRQGRVWIRIFPDLPVSTKPAEVRMGSGK---------GSPEFWAARVHP-GRIMFEV--DG-- VPLDLAKRAFELAAAKLPIKTRF-IQNELNARRKQRVRARI--KKYGSGRPRLSVFRSSKHIYAQIIDD---T--AGHTL AAASSL-DKDL-REGL----KTG-ADIDAAKAVGKLIAER--ATAKG-VTAVVFDRGAYLFH--GRVKALADAAREAGLQ F-------------------------------------------------------------ENE-AQAFARLIRSSPRK LNLVAQLIRGKAAGEALALLTFS---------------------------------KRRVAGEVKKVLQSAIAN----A- ENNH-QLDVDRLYVSHATVGRALVMKRFHARARGRGARVEKWFSNLTVVVREAAKIRKNDRVVVLTGK------DK-GKT GEVIEVLPKEN--RVK--VRGVNLVKKHQR----PT--PT--QQ-GGIVEIEAALHVSNVA-HIDPKT-------SK--P --TRVGFKT---LE--------DGKVR---VAKASG---EII--MGQKVNPVGLRLG--IN-RTWDSRWFA------A-R D--YAVLLHQDLKLRKFL--QGKLQ-----AAGVSRIVIERPA-K-KARVTIHTARPGVVIGKKGADIEKLRGTLGTMVS LNIVEIRK---PELDARLIAENIASQLERRVAFRRAMKRAVQSAMRL-GAQGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADIDYGTATAKTTYGTCGVKVWVFMNLSDPLGDMLTRIRNGQKARMSVITS-PASKLRTNVLEVLKREGYIRGYN VED--VRP--------GVRNLRIELKYH----EG-------E---PVIKEIHRVSKPGRRIYSKIADLPRVYNGLGIAIL STPRGVMSDAEARAANVGGEVLCKVFMESQNIRIRLKAFDHRVLDQSTSEIVNTAKRTGARVRGPIPLPTQIEKFTVNRS PHIDKKSR-EQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKIRRILQGTVVSDKGDKTVIVLVERRVMHPVYK KFIKQSKKYAAHDEA--NAFKIGDVVQIEECRPISKRKRWTVVT--AAE------------------------------- -MTRSV-WKGPFVDG-YLLKKAEKARA---SGRNE----IIKIWSRRSTILPQFVGLTFGVYNGQKFLPVLVTE-NMIGH KFGEFSPTRTFYGHA------A---DK----KAK------RK >ALPHA_Rhodospirillum_rubrum_ATCC_11170 Concatenation of 2 sequences MALKQYNPVTPGMRNLVLVDRSD-LYKG------------KP-VKKLTEGLVKTGGRNNHGRVTSWW-RGGGNKRR---- YRLIDFK-R--TK-VDVAGRVERLEYDPNRTAFIALITYE-DGEQTYILAPQRLQVGDAVISAD-R-AD-IKPGNAMPLK NMPVGTIIHNVEMKPGKGGQLARSAGCYAQLIGK--DAGYAQLRLSSGELRLVRGECLATVGAVSNPDNQNEKLGKAGRS -RWM-----GRR-P-HVRGVVMNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKRTR-SNKKTDS---LIMRSR --------------------------------MRS---G-LIAQKVGMTRLFT-DEGT---------HVPVTVLKVEACQ VVAVR----TSE----T--DGY--TAVQLGA-------GV--ATSK----------AMRGHFA----------------- ---AK-VEPKKKVVEFRV--------SEDCLL-----EP---GA-ELSA--A-H-FVAGQKVDIAGTTIGKGFAGAMKRH NFRG-LEATHGVSVSHRS-HGSTGQC-QDPG-RVFKGKKMAGHMGDTRITQQSLTVVATDADRG---------------- ----------LILVKGS-VPGADGAWLEVR--MKCDVKT-LDGKDA-GSIELSDSVF----GL-PV-RTDLLHRMVRWQL ARRQAGTHKTKGISE--------IS-GTTAKPF---------KQKGTGHAR--------QGS---KR-SP----QF---- RGGATIFGPV-V-RSHAHDLNKKVRKLGLKTALSAKAQAG----------------Q-LIVLDQA----ISE-S------ --GKTKLFI--DGPEN--E---KFALAARNIIGLD-V---------------LPQQGANVYDILRRDT----LVLTKEAV KHLEARLQEHYQTVV----KKALLEKFQYGNVMEIPRLEKIVINMGVG-EASQDRKLIEGALTDMTAISGQKPIITRAKK SIAAFKLREQMIVGCKVTLRRDRMFEFLDRLVTIALPRVRDFRGVSA-KSFDGRGNYNMGLKEQIVFPEID-----YDRV DKVRGMDITICTS-----------------------AKSDEEAKALLEGFAMPFMSRVG-K--YPVTVPAGVTIT-V--- -K-D--N-VVTAKGKLGEMTYTA--AG-E--VETRLED-NL--IWV----K-P-LSETKHAR-QQWGTTRARINNLVRGV SEGFSRKLELVGVGY--KAAAQG-KV--LKLS--LGFSHDVDFPI-P-E-DLKITTP--A-PNQIEISG-VDKQRVGQIA SEIRSYR------SPEPY---KGKGVKYAGEQILRKEGK----------MIQMQTRLDVADNSGARQVQCIKVLG-SKRM I--AGVGDIIVVSVKEAIPR-G-------RVKKGDVHRAVIVRTAKEIRRPDGTSIRFDRNAAVLLN-KQNE-PIGTRIF GPVVRELR-ARKFMKIISLAPEVLMK-L--NELRDNPGA-TKNRIRVG-RGIGSGK-GKTAGRGVKGQKSREGVS-I--- --NGF-E-GGQMPIYRRLPK-RG--FNNVNLDRIITEKALIEA-GLVRVR---------LLG--KGE-L-S-V-K-VAI- EVAGASATAREGVEKAGGTL-K---QHK--GRI---HGLA-KGGTDLNFG----------SFGLKAV--EPERVTARQIE AARRAITRHM------KRQGRLWIRIFPDVPVSKKPAEVRMGSGK---------GSPEFWVARVKP-GRVMFEL--DG-- VPEDIARGAFELAAAKLPLKTKF-ISSELFERRRSRNRYQI--RLKSAGRLRLSVFRSNKHMYAQIIDD---A--EGRTL VSASTV-DKEL-RGNL----TKG-GDKAAAAEVGKLLAER--AKAAG-YTEVVFDRGGYKYH--GRVQALADAAREAGLS F-------------------------------------------------------------DTE-ARAITKMIRTSPYK LNLVAESIRGKTAERALAELTFS---------------------------------KRRMADTVKKTLQSAIAN----A- ENNH-QLDVDQLIVSEAYVGKAMVLKRWRARARGRVGKILKPFSNLTIVVREAAKIKKGDKVVVLAGK------DK-GKR GEVLKAIPKEG--RVV--VQGVNVVKRHTR----PT--NT--AA-GGIVEKEASIHVSNVA-HEDPKD-------GS--P --TRVGFKV---LE--------DGKVR---YAKRSG---DVI--MGQKVNPIGLRLG--IN-RTWDSRWFA------G-R D--YASLLHQDLAIKKYL--KSKLA-----QAGVSRIVIERPA-K-KARITIHTARPGVVIGKKGQDIENLRKKLQVMVH LNIVEIRK---PELDAQLVAENIAQQLERRVAFRRAMKRAVQSAMRL-GALGIRINCGGRLGGAEIARTEWYREGRVPL- -HTLRADVDYGTAAAHTTYGVCGVKVWVFMALSDPIGDMLTRIRNGQRARKSSVMA-PASTMRANVLDVLIREGYIRGYE KVD--VRK--------GIAELRVELKYH----EG-------E---PVIREIARVSTPGRRVYSKIKDLPKVYNGLGISIL STPRGVMSDHEARQANVGGEVLCRVFMESQNIRIRLKAFDHRVLDQSTREIVSTAKRTGAQVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRIMQGVVVSDKMDKTIVVQVERRFKHAVYK KFIKRTKKFAAHDEL--NQFKIGDLVRIRECAPISRRKTWEVVL--DNA------------------------------- -MARSV-WKGPFIDG-YLLNKAEKARS---SGRNE----VIKIWSRRSTIMPQFVGLTFGVYNGQKFVPVLVTE-QMVGH KFGEFAPTRTYYGHA------A---DK----KAK------RK >ALPHA_Rickettsia_akari_Hartford Concatenation of 2 sequences MALRNFNPITPSLRELVQVDRTS-LWKG------------RP-LKSLTKGISKTGGRNNQGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDISAVVERIEYDPNRTAFIALIKYE-DGEYSYILAPQKLSVGDRVMSSQ-D-AD-IKIGNCLPLK FIPVGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDRKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKRTSK---FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RIPLTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGI-------KD--KVTK----------PMKQVFN----------------- ---AK-ISPKTKLKEFRI--------SEGNFI-----DI---AA-NLEV--D-H-FMAGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNQVTIQNLKIFAVDRERK---------------- ----------LIMIRGS-IPGHKNSYLSIK--MKTKILS-LANEEV-GEISLNEDIF----AV-EFIRDDVIKQVIDWQR AKAMSGNHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVAHGPR-V-RSHVTKLPKKVRKLGLIHALSEKFAEG----------------R-LLVIDSL----KLD-Q------ --PKTSFVI--DGNED--T---NFSLAAKNIYNTA-I---------------VPQIGANVYDIIRYEY----VLLSQEAV SVLELRFKELYQQKI----IENLQKEFSYKNKHEIPQIKKIVINMGVG-EAIADSKVINNAVNDLTCISGQKPVVTLARK SIATFKLRESMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSD-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDKESKFLLSGFNLPFMSRVG-K--LPITIPEGVTVG-L--- -N-D--L-EVKISGPKGELSKIF--KG-N--IAISLAE-NK--LLV----K-P-LAANKSAR-AMWGTARSIISNMVIGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-HIKIDVP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFDNQFIPRKEGK----------MIQMQSILEVADNSGARKVMCIKVLG-SHHM V--AKLGDVIVVSVKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRPDGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-TKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGVGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLVEV-GLINVK---------LLSICSDD-F-S-S-P-LSL- KLDAYSSKAKDLIKKAGGKL-K---AHK--GRV---ASKA-KAGTMLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSKKPAEVRMGKGK---------GSPEFFAVRVSP-GKIMFEI--EG-- VEENIALRALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---SKTSNRVRLSIFKSCRHIYAQIIDD---S--RSITI ASASTL-DEKI-TTLK----KSY-CNIDNAIKVGEAIAKK--ADSAG-IKEVVFDRGGYKYH--GVVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAKAKSVRVSPRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------SKRIAKVVKGCLQSAVAN----A- ENNL-GLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVRKGDEVIVITGK------HK-GKK GKILKVFPEDS--KVI--VAGVNLVKKHTK----PN--Q--MSG-GGIITKELPIHISNIA-HIDPKT-------GD--P --TKVAFKC---LD--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSVLYA------E-K H--YKTLFIQDLKIRDLI--NKGFN-----QAQVSRVLIERPSNK-SIIISINAKKPNIIIGRNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASLKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILDVLQKEGYIKDYV TTQ----K---N----NISYAEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSAIKALKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHHSLDQATKEIVSAVKRTFASINGPIPLPRKIERFTVNRS PHVHKKSR-EQFEIRKHKRLLVIDDPNPAVVDALSKVDLAAGVDVVIELRRVLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NKYQEGDKVSIIESRPISKTKTWIVVN----G------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFVPVSVNE-EMVGK KLGDFAPTRTFYGHG------A---DK----KVK------RK >ALPHA_Rickettsia_bellii_OSU_85-389 Concatenation of 2 sequences MALKSFNPITPSLRELVQVDRTS-LWKG------------RP-FKALTKGISKTGGRNNQGRITSWQ-RGGGHKRL---- YRVIDFK-R--NK-LDISAIVERIEYDPNRTAFIALIKYE-DGEHAYILAPQKLVVGDKIISSK-D-AD-IKIGNCLPLR YIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLKSGEFRLVPLDCMATIGTVSNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKRTSK---FIIKKR --------------------------------MRT---G-IIAQKVGMTSVFN-NNGK---------RVPLTLVKVDDCQ VVGHK----IAE----K--HGY--NALVIGI-------KD--KVTK----------PMKQVFN----------------- ---AK-VSPKTKLKEFRI--------SEDNFI-----DI---AA-SLEV--D-H-FTAGQFIDVTATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCSQVTIQNLKIFAIDKEQG---------------- ----------LIMIQGS-IPGHKGSYISIK--MKTKILN-LANEEI-GEISLNEDIF----AV-EFIRDDIIKQVVDWQR AKAMAGTHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVIHGPV-V-RSHATKLPKKVRKLGLIHALSEKFSEG----------------K-LLVIDSL----KLE-T------ --PKTSFVI--DGNED--V---NFSLAAQNIYNTV-V---------------VPQIGANVYDIIRHEY----VLLSQEAV NVLELRFKELYQKEI----ISNLQKEFSYKNKHEIPAIEKIVINMGVG-EAIADSKVIDKAVNDLTLISGQKPFVTSARK SIATFKLRDGMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DSIRGMDITIVTS-----------------------AKTDKEGKSLLSGFNLPFMSCVG-K--LPIIIPEGVKVG-L--- -N-D--L-EVKISGPKGELSKSF--KG-S--IGISLAE-NK--LLV----K-P-LSSSKSAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMMKG-KY--LNLM--LAKSHNTKIEI-P-S-HIKVEVP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFEDQFIPCKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSIKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRADGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRVA-RGIGSGK-GKTAGRGVKGQKSRAGVA----- -IKGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLIEI-GLINVK---------LLSICSDD-F-N-Y-P-LSF- KLDSYSSKAKEIVEKAGGKL-K---AHK--GRV---VSKS-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDLPVSKKPAEVRMGKGK---------GNPEFFAVRVSP-GRIMFEI--EG-- VEEDVAVKALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---AKTANRARLSIFKSGRHIYAQIIDD---T--KSVTI ASASTL-DEKI-KKLK----KSH-CNVENATKIGELIAEK--AVSCG-VEEVVFDRSGYKYH--GVVKALADAARKK-IR F-------------------------------------------------------------KNF-ATAKAKSIRVSPRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRISKVVKACLQSAVAN----A- ENNL-GLDIDRLVITNATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVIVITGK------YK-GKK GKILKVFSE----------------------------------------------------------------------- --------------------------------------------MGQKVCAHGFRVGPTLI-KGWDSVFYA------E-K Q--YKTLFIQDLKIRELV--NKSFT-----QAQVSRILIERPSNK-SIIININAKKPNIIIGKNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIASQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILEVLQKEGYIKNYT STP----K---D----NISYTEVTLKYS---ANG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANISGPIPLPRKIQRFTVNRS PHVHIKSR-EQYEIRTQKRLLVIDDPNPVVVDALSKVDLAAGVDVVIELKRVLQGVVISSKTDKTVTVKVERRFKHPIYK KFIKVSKKYAAHDPN--NKFQEGDKVNIIESRPISKTKTWVVIN----E------------------------------- -MARSV-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFSPTRTFHGHG------A---DK----KVK------RK >ALPHA_Rickettsia_bellii_RML369-C Concatenation of 2 sequences MALKSFNPITPSLRELVQVDRTS-LWKG------------RP-FKALTKGISKTGGRNNQGRITSWQ-RGGGHKRL---- YRVIDFK-R--NK-LDISAIVERIEYDPNRTAFIALIKYE-DGEHAYILAPQKLVVGDKIISSK-D-AD-IKIGNCLPLR YIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLKSGEFRLVPLDCMATIGTVSNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKR-TS-K-FIIKKR --------------------------------MRT---G-IIAQKVGMTSVFN-NNGK---------RVPLTLVKVDDCQ VVGHK----IAE----K--HGY--NALVIGI-------KD--KVTK----------PMKQVF------------------ ---NAKVSPKTKLKEFRI--------SEDNFI-----DI---AA-SLEV--D-H-FTAGQFIDVTATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCSQVTIQNLKIFAIDKEQG---------------- ----------LIMIQGS-IPGHKGSYISIK--MKTKILN-LANEEI-GEISLNEDIF----AV-EFIRDDIIKQVVDWQR AKAMAGTHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVIHGPV-V-RSHATKLPKKVRKLGLIHALSEKFSEG----------------K-LLVIDSL----KLE-T------ --PKTSFVI--DNEVD--V---NFSLAAQNIYNTV-V---------------VPQIGANVYDIIRHEY----VLLSQEAV NVLELRFKELYQKEI----ISNLQKEFSYKNKHEIPAIEKIVINMGVG-EAIADSKVIDKAVNDLTLISGQKPFVTSARK SIATFKLRDGMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DSIRGMDITIVTS-----------------------AKTDKEGKSLLSGFNLPFMSCVG-K--LPIIIPEGVKVG-L--- -N-D--L-EVKISGPKGELSKSF--KG-S--IGISLAE-NK--LLV----K-P-LSSSKSAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMMKG-KY--LNLM--LAKSHNTKIEI-P-S-HIKVEVP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFEDQFIPCKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSIKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRADGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRVA-RGIGSGK-GKTAGRGVKGQKSRAGVA----- -IKGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLIEI-GLINVK---------LLSICSDD-F-N-Y-P-LSF- KLDSYSSKAKEIVEKAGGKL-K---AHK--GRV---VSKS-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDLPVSKKPAEVRMGKGK---------GNPEFFAVRVSP-GRIMFEI--EG-- VEEDVAVKALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---AKTANRARLSIFKSGRHIYAQIIDD---T--KSVTI ASASTL-DEKI-KKLK----KSH-CNVENATKIGELIAEK--AVSCG-VEEVVFDRSGYKYH--GVVKALADAARKK-IR F-------------------------------------------------------------KNF-ATAKAKSIRVSPRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRISKVVKACLQSAVAN----A- ENNL-GLDIDRLVITNATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVIVITGK------YK-GKK GKILKVFPEQN--KIV--VSGINLVKKHTK----PT--KV--SE-GGIITKELPIDISNVA-HVDPKT-------GN--P --TKVAFKF---LE--------DGKVR---IAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSVFYA------E-K Q--YKTLFIQDLKIRELV--NKSFT-----QAQVSRILIERPSNK-SIIININAKKPNIIIGKNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIASQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILEVLQKEGYIKNYT STP----K---D----NISYTEVTLKYS---ANG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANISGPIPLPRKIQRFTVNRS PHVHIKSR-EQYEIRTQKRLLVIDDPNPVVVDALSKVDLAAGVDVVIELKRVLQGVVISSKTDKTVTVKVERRFKHPIYK KFIKVSKKYAAHDPN--NKFQEGDKVNIIESRPISKTKTWVVIN--EE-------------------------------- -MARSV-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFSPTRTFHGHG------A---DK----KVK------RK >ALPHA_Rickettsia_canadensis_McKiel Concatenation of 2 sequences MALKNFNPITPSLRALVQVDKTS-VWKG------------RP-FKSLTKGISKTGGRNNHGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDISAVVERIEYDPNRTAFIALIKYE-DGQYSYILAPQKLSVGDKVISSQ-D-AD-IKIGNCLPLK FIPIGTTVHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLIPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKRTSK---FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RIALTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGV-------KD--KVTK----------PMKQVFN----------------- ---AK-ISPKTKLKEFRI--------SEENFI-----DV---AA-SLEV--D-H-FMAGQFVDITAITIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNQVTIQNLKIFAVDKDRK---------------- ----------LIMIQGS-IPGHKNSYLSIK--MKTKILS-LANEEV-GEISLNKDIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGLAHGPI-V-RSHATQLPKKVRKLGLIHALSEKFAEG----------------K-LLVIDSL----KLD-K------ --PKTSFVI--DGNED--I---NFSLAAKNIYNTV-I---------------VPQIGANVYDIIRHEY----VLLSQEAV NVLELRFKELYQQEI----IENLQKEFSYKNKHAIPQIKKVVINMGVG-EAIADSKVINNAVNDLTLISGQKPVVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDKESKFLLSGFNFPFMSRIG-K--LPITIPEGVKVS-L--- -N-D--L-EVRISGPKGELSKTF--KG-N--IVVLLAE-NK--LLV----K-P-LAVSKNAR-AMWGTARSIISNMVTGV KEGFQLKLEVNGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-P-DIKIDVP--K-QNIIILEG-IDKEKLGQFA SIIIKQR------PPEPY---KGKGIRFENQFIPRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVISVKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRPDGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKRKKRIA-RGIGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPIIKRLPK-RG--FNCVNIYNIITKEKLIEA-GVVNVK---------LLSLCSDD-F-A-T-P-LSL- KLDAYSSKAKDFIEQAGGKL-K---AHK--GRV---VSKA-KAGTTLAFG----------SFGLKSI--DSWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSKKPAEVRMGKGK---------GSPEFFAVRVAP-GRIMFEI--AG-- VEENIAIRALELASTKLPVRTRI-VAKLKFEKRRSRIRHKI---SQTSNRVRLSIFKSCRHIYAQIIDD---S--KSITI ASASTL-DAKI-KKLK----KSH-CNIENAIKVGKAIATK--ADSAG-IKEVVFDRGGYKYH--GVVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAKAKSIRVSPRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRIAKVVKTCLQSAIAN----A- ENNL-GLDIDRLVVTKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVIVITGK------HK-GKK GKILKVFPEDS--KVI--VAGVNLVKKHTK----PN--QM--SE-GGIRTKELPIHISNIA-HIDPKT-------GR--P --TKVVFKF---LE--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSVLYA------E-K H--YKTLFIQDLKIRDLI--NNSFN-----QAQISRVLIERPSNK-SIIININAKKPNVIIGRSGNEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILDVLQKEGYIKDYI ITH----K---N----NISYTEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRILDQATKEIVSAIKRTFANINGPIPLPRKIERFTVNRS PHVHKKSR-EQFEIRKHKRLLVIDDPNPAVVDALSKVDLAAGVDVVIELKRVLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NRYQEGDKVSIIESRPISKTKTWIVVN----G------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFAPTRTFYGHG------A---DK----KVK------RK >ALPHA_Rickettsia_conorii_Malish_7 Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTS-LWKG------------RP-LKSLTKGISKTGGRNNQGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDISAIVERIEYDPNRTAFIALIKYE-DGEYSYILAPQKLSVGDRVISSQ-D-AD-IKIGNCLPLK CIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKR-TS-K-FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RISLTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGV-------KD--KVTK----------PMRQVFN----------------- ---AK-ISPKTKLKEFRI--------SEENFI-----DI---AA-SLEV--D-H-FTAGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNKVTIQNLKIFAVDKERK---------------- ----------LIMIQGS-IPGHKNSYLSVK--MKTKILS-LANEEV-GEISLNEDIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VL-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVAHGPR-V-RSHATKLPKKVRKLGLIHALSEKCAEG----------------K-LLVIDSL----KLD-K------ --PKTSFVI--DNEVD--I---NFSLAAKNIYNTV-I---------------VPQIGANVYDIIRHEY----VLLSQEAV SVLELRFKELYQQKI----IENLQKKFSYKNKHEIPQIKKIVINMGVG-EATADSKVINNAVNDLTLISGQKPVVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDQESKFLLSGFNLPFMSRVG-K--LPITIPEGVKIG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAISLAE-NK--LLV----K-P-LAANKNAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-DIKIEMP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENQCIPRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSVKDAIPG-G-------KVKKGDVYKGVIVRTKTGVVRPDGSTIKFDQNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGIGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPIIKRLPK-RG--FNCINIYNIITKEKLVEA-RVVNVK---------LLSICSDD-F-A-A-P-LSL- KLDAYSSKAKDLIEKAGGKL-K---AHK--GRV---ASTA-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSKKPAEVRMGKGK---------GSPEFFAVRVSP-GRIMFEI--EG-- VEENVALRALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---SKTSNRVRLSIFKSGRHIYAQIIDD---S--KSITI AAASTL-DEKI-KKLK----KSH-CNIENAIKVGEEIAKK--ADSAG-IKDVVFDRGGYKYH--GVVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAQAKSIRVSSRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRIAKVVKDCLQSAVAN----A- ENNL-GLDIDRLVVTKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVVVITGK------HK-GKK GKILKVFPEDS--KVI--VSGVNVVKKHTK----SN--QM--SE-GGIITKELPIHISNIA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSILYA------E-K H--YKTLFIQDLKIRDLI--NKGFN-----QAQISRVLIERPSNK-SIIININAKKPNIIIGRNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILDVLQKEGYIKDYI TTQ----K---N----NISYTEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANINGPIPLPKKIGRFTVNRS PHVHKKSR-EQFEIRKHKRLLVIGDPNPAVVDALSKVDLAAGVDVVIELKRVLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NKYQEGDKVSIIESRPISKTKTWVVVN----G------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFAPTRTFHGHG------A---DK----KIK------RK >ALPHA_Rickettsia_felis_URRWXCal2 Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTS-LWKG------------RP-LKSLTKGISKTGGRNNQGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDISAIVERIEYDPNRTAFIALIKYE-DGEYSYILAPQKLSVGDRVISSQ-D-AD-IKIGNCLPLK FIPTGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKRTSK---FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RISLTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGI-------KD--KVTK----------PMKQVFN----------------- ---AK-ISPKTKLKEFRI--------SEENFI-----DI---AA-SLEV--D-Y-FTAGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNQVTIQNLKIFAVDKERK---------------- ----------LIMIQGS-IPGHKNSYLSVK--MKTKILS-LANEEV-GEISLNEDIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVAHGPR-V-RSHATKLPKKVRKLGLIHALSEKFAEG----------------K-LLVIDSL----KLD-K------ --PKTSFVI--DGNED--T---NFSLAAKNIYNTV-I---------------VPQIGANVYDIIRHEY----VLLSQEAV SVLELRFKELYQQKI----IENLQKEFSYKSKHEIPQIKKIVINMGVG-EAIADSKVINNAVNDLTLISGQKPVVTLARK SIATFKLRESMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDKESKFLLSGFNLPFMSRVG-K--LPITIPEGVKVG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAISLEE-NK--LLV----K-P-LAANKNAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-DIKIEVP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENQFIPRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSVKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRPDGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGIGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLVEV-GVVNVK---------LLSICSDD-F-A-S-P-LSL- KLDAYSSKAKDLIEKAGGKL-K---AHK--GRV---ASKA-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSKKPAEVRMGKGK---------GSPEFFAVRVSP-GRIMFEI--EG-- VEENVALRALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---SKTSNRVRLSIFKSGRHIYAQIIDD---S--KSITI ASASTL-DKKI-KKFK----KSH-CNIENAIKVGEEIAKK--ADSAG-IKEVVFDRGGYKYH--GVVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAKAKSIRVSPRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKKIAKVVKDCLQSAVAN----A- ENNL-GLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVVVITGK------HK-GKK GKILKVFPEDS--KVI--VSGVNLVKKHTK----PN--QM--SE-GGIITKELPIHISNIA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSVLYA------E-K H--YKTLFIQDLKIRDLI--NKGFN-----QAQVSRVLIERPSNK-SIIININAKKPNIIIGRNGSEIDKIKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGIIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILDVLQKEGYIKDYV TTQ----K---N----NISYTEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANINGPIPLPRKIERFTVNRS PHVHKKSR-EQFEIRKHKRLLVIDDPNPAVVDALSKVDLAAGVDVVIELKRVLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NKYQEGDKVSIIESRPISKTKTWLVVN----G------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFAPTRTFHGHG------A---DK----KVK------RK >ALPHA_Rickettsia_massiliae_MTU5 Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTS-LWKG------------RP-LKSLTKGISKTGGRNNQGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDISAIVERIEYDPNRTAFIALIKYE-DGEYSYILAPQKLSVGNRVISSQ-D-AD-IKIGNCLPLK CIPIGTTLHNVEMQVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKRTSK---FIVKKR --------------------------------MRT---G-IIAQKVGMTSVFN-DKGE---------RISLTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGV-------KD--KVTK----------PMKQVFN----------------- ---AK-ISPKTKLKEFRI--------SEEHFI-----DI---AT-SLEV--D-H-FTAGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFRGKKMAGHMGCNQVTIQNLKIFAVDKERK---------------- ----------LIMIQGS-IPGHKNSYLSVKMKMKTKVLS-LANKEV-GEISLNENIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VL-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVAHGPR-V-RSHATKLPKKVRKLGLIHALSEKCAEG----------------K-LLVIDSL----KLD-K------ --PKTSCVI--DGNED--I---NFSLAAKNIYNTV-I---------------VPQIGANVYDIIRHEY----VLLSQEAV SVLELRFKELYQQQI----IENLRKKFSYKNKHEIPQIKKIVINMGVG-EATADSKVINNAVNDLTLISGQKPVVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDQESKFLLSGFNLPFMSRVG-K--LPITIPEGVKIG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAISLVE-NK--LLV----K-P-LAANKNAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-DIKIEMP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENQFIPRKEGK----------MIQMQSMLEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSVKDAIPG-G-------KVKKGDVYKGVIVRTKTGVVRPDGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGIGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLVEA-GVVNVK---------LLSICSDD-F-T-S-P-LSL- KLDAYSAKAKDLIEKAGGKLKK---AHK--GRV---ASKA-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSQKPAEVRMGKGK---------GSPEFFAVRVSP-GRIMFEI--EG-- VEENVALRALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---SKTSNRVRLSIFKSGRHIYAQIIDD---S--KSITI ASASTL-DEKI-KKLK----KSH-CNIENAIKVGEEIAKK--ADSAG-IKDVVFDRGGYKYH--GIVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAQAKSIRVSSRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRIAKVVKDCLQSAVAN----A- ENNL-GLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVVVITGK------HK-GKK GKILKVFPEDS--KVI--VFGVNLVKKHTK----SN--QM--SE-GGIITKELPIHISNIA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---VAKKSG---EIIK-MGQKVCAHGFRVGPTLI-KGWDSVLYA------E-K H--YKTLFIQDLKIRDVI--NKGFN-----QAQISRVLIERPSNK-SIIININAKKPNIIIGRNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKISILDVLQKEGYIKDYI TTQ----K---N----NISYTEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSPIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANINGPIPLPRKIGRFTVNRS PHVHKKSR-EQFEIRKHKRLLVIGDPNPAVVDALSKVDLAAGVDVVIELQRVLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NKYQEGDKVSIIESRPISKTKTWVVVN----G------------------------------M SMARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFAPTRTFHGHG------A---DK----KVK------RK >ALPHA_Rickettsia_prowazekii_Madrid_E Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTN-LWKG------------RP-LKTLTKGMSKTGGRNQQGRITSWH-RGGGHKKL---- YRVIDFK-R--KK-IDISAIVERIEYDPNRTAFIALIKYD-DGEYSYILAPQKLSIGDRVISSQ-A-AD-IKIGNCLPLK SIPIGTTLHNVEMKIGKGGQIARSAGTSVELVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFSTKGKKTR-KNKRTSK---FIVKKR --------------------------------MRT---G-IIAQKVGMTSVFN-DKGE---------RISLTLVKVDDCQ VVGHK----TLA----K--HGY--NALVIGV-------KD--QVTK----------PMKQVFN----------------- ---AK-IAPKTKLKEFRI--------SEDNFI-----DI---AS-ILEV--D-H-FRVGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNKVTIQNLKIFAVDTNRK---------------- ----------LIMIQGS-IPGHKNSYLLVK--MKTKILS-LANEEV-GEITLNKDIF----AV-EFIRDDIIKQVIDWQR AKAMFGNHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGISHGPK-V-RSHAIKLPKKVRKLGLIHALSEKYAEE----------------K-LLIIDSL----KLD-K------ --PKTSFVI--DGNKD--I---NFSLATKNIYNTL-I---------------VPQIGANVYDIIRHEY----VLLSQEAV SFLELRFKELYKQKI----IESLKKEFSFKNKHEIPKIKKIVINMGVG-EAIADSKVINNALNDLTLISGQKPVVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDQESKFLLSGFNLPFMSRVG-K--LPITIPEGVKVG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAIIMEE-NK--LVV----K-P-LAVNKNAR-AMWGTARSIICNMITGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-NIKIDLP--K-QNIILLEG-IDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENKFIQRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM M--AKLGDVIVVSIKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRSDGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNLGA-KKNKKRIA-RGIGSGK-GKTAGRGIKGQKSRSGVA----- -IKGF-E-GGQTPMIKRLPK-RG--FKCINIYNIITKEKLLEV-GLINVK---------LLSICSDD-F-A-S-P-LSL- KLDAYSSKAKYLIEKVGGQL-K---AHK--GRV---MSKA-KAGMTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSKKPAEVRMGKGK---------GTPEFFAVRVSP-GRIMFEI--EG-- VEENIALRALELASAKLPVRTRI-VAKLKFEKRKSRIRYKI---SKTSNRMRLSIFKSCRHIYAQIIDD---S--KSITI AAASTL-DKKI-KKIK----KSH-CNIENAIKVGKEIAKK--ADSAG-IKEVVFDRGGYKYH--GIIKALADAAREK-IK F-------------------------------------------------------------KNF-ATAKAKSIRVSPRK LNLVASFIRNMKVSEALVQLTFS---------------------------------PKRIAKIVKDCLQSAIAN----A- ENNL-GLDIDRLIITKATVGKSVVMKRIMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVVIITGK------YK-GKK GKVLKVFPEEN--TVV--VSGVNLVKKHTK----PN--KM--SE-GGIITQESPIHISNIA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KDWDSILYA------E-K H--YKTLFIQDLKIRDLI--NKWFN-----QAQISRVLIERPSNK-SIIININAKKPNIIIGKNGTEIDKLKKAIENMVY INIHEVRK---FNIDAAIVAQTIAAQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILDVLQKEGYIKDYV TTQ----K---N----NISYTEVALKYS---VNG-------E---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFATINGPIPLPRKIERFTVNRS PHVHKKSR-EQFEIRKHKRLLVIDDPNPAVVDALSKVDLAAGVDVVIELKRVLQGVVISSKTDKTVTVKVERKFKHPIYK KFVKVSKKYAAHDIE--NKYKEGDKVSIVESRPISKTKTWVVLNLE---------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLMK---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVYINE-EMVGR KLGEFAPTRTFHGHG------A---DK----KVK------RK >ALPHA_Rickettsia_rickettsii_Iowa Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTS-LWKG------------RP-LKSLTKGISKTGGRNNQGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDVSAIVERIEYDPNRTAFIALIKYE-DGEYSYILAPQKLSVGDRVISSQ-D-AD-IKIGNCLPLK CIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKRTSK---FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RISLTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGV-------KD--KVTK----------PMRQVFN----------------- ---AK-ISPKTKLKEFRI--------SEENFI-----DI---AA-SLEV--D-H-FTAGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNQVTIQNLKIFAVDKERK---------------- ----------LIMIQGS-IPGHKNSYLSVK--MKTKILS-LANEEV-GEISLNEDIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VL-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVAHGPR-V-RSHATKLPKKVRKLGLIHALSEKCAEG----------------K-LLVIDSL----KLD-K------ --PKTSFVI--DGNED--I---NFSLAAKNIYNTV-V---------------VPQIGANVYDIIRHEY----VLLSQEAV SVLELRFKELYQQKI----IENLQKKFSYKNKHEIPQIKKIVINMGVG-EATANSKVINNAVNDLTLISGQKPVVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDQESKFLLSGFNLPFMSRVG-K--LPITIPEGVKIG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAISLAE-NK--LLV----K-P-LAAKKNAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-DIKIEMP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENQFIPRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSVKDAIPG-G-------KVKKGDVYKGLIVRTKTGVVRPDGSTIKFDQNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGIGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLVEA-RVVNVK---------LLSICSDD-F-A-A-P-LSL- KLDAYSAKAKDLIEKAGGKL-K---AHK--GRV---ASTA-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSQKPAEVRMGKGK---------GSPEFFAVRVSP-GRIMFEI--EG-- VEENVALRALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---SKTSNRVRLSIFKSGRHIYAQIIDD---S--KSITI AAASTLDEKRK---------KSH-CNIEHAIKVGEEIAKK--AYAAG-IKDVVFDRGGYKYH--GVVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAQAKSIRVSSRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRIAKVVKDCLQSAVAN----A- ENNL-GLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVVVITGK------HK-GKK GKILKVFPEDS--KVI--VSGVNVVKKHTK----PN--QM--SE-GGIITKELPIHISNIA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSILYA------E-K H--YKTLFIQDLKIRDLI--NKGFN-----QAQISRVLIERPSNK-SIIININAKKPNIIIGRNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKTSILDVLQKEGYIKDYI TTQ----K---N----NISYTEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFAKINGPIPLPKKIGRFTVNRS PHVHKKSR-EQFEIRKHKRLLVIGDPNPAVVDALSKVDLAAGVDVVIELKRLLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NKYQEGDKVSIIESRPISKTKTWVVVN----G------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFAPTRTFHGHG------A---DK----KIK------RK >ALPHA_Rickettsia_rickettsii_Sheila_Smith Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTS-LWKG------------RP-LKSLTKGISKTGGRNNQGRITSWH-RGGGHKKL---- YRIIDFK-R--NK-IDVSAIVERIEYDPNRTAFIALIKYE-DGEYSYILAPQKLSVGDRVISSQ-D-AD-IKIGNCLPLK CIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGFPTKGKKTR-KNKR-TS-K-FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RISLTLVKVDDCQ VVGHK----TLE----K--HGY--NALVIGV-------KD--KVTK----------PMRQVFN----------------- ---AK-ISPKTKLKEFRI--------SEENFI-----DI---AA-SLEV--D-H-FTAGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNQVTIQNLKIFAVDKERK---------------- ----------LIMIQGS-IPGHKNSYLSVK--MKTKILS-LANEEV-GEISLNEDIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VL-GTTKKPF---------KQKGTGNAR--------QGS---LR-SV----QM---- RGGGVAHGPR-V-RSHATKLPKKVRKLGLIHALSEKCAEG----------------K-LLVIDSL----KLD-K------ --PKTSFVI--DNEVD--I---NFSLAAKNIYNTV-V---------------VPQIGANVYDIIRHEY----VLLSQEAV SVLELRFKELYQQKI----IENLQKKFSYKNKHEIPQIKKIVINMGVG-EATANSKVINNAVNDLTLISGQKPVVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDQESKFLLSGFNLPFMSRVG-K--LPITIPEGVKIG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAISLAE-NK--LLV----K-P-LAAKKNAR-AMWGTARSIISNMVTGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-DIKIEMP--K-QNIIILEG-TDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENQFIPRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM V--AKLGDVIVVSVKDAIPG-G-------KVKKGDVYKGLIVRTKTGVVRPDGSTIKFDQNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGIGSGK-GKTGGRGIKGQKSRSGVA-I--- --KGF-E-GGQTPMIKRLPK-RG--FNCINIYNIITKEKLVEA-RVVNVK---------LLSICSDD-F-A-A-P-LSL- KLDAYSAKAKDLIEKAGGKL-K---AHK--GRV---ASTA-KAGTTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSQKPAEVRMGKGK---------GSPEFFAVRVSP-GRIMFEI--EG-- VEENVALRALELASAKLPVRTRI-VAKLKFEKRRSRIRHKI---SKTSNRVRLSIFKSGRHIYAQIIDD---S--KSITI AAASTLDEKRK---------KSH-CNIEHAIKVGEEIAKK--AYAAG-IKDVVFDRGGYKYH--GVVKALADAAREK-IK F-------------------------------------------------------------KNF-ATAQAKSIRVSSRK LNLVAAFIRNMKVSEALVQLTFS---------------------------------PKRIAKVVKDCLQSAVAN----A- ENNL-GLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKLKVKKGDEVVVITGK------HK-GKK GKILKVFPEDS--KVI--VSGVNVVKKHTK----PN--QM--SE-GGIITKELPIHISNIA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---VAKKSG---EII--MGQKVCAHGFRVGPTLI-KGWDSILYA------E-K H--YKTLFIQDLKIRDLI--NKGFN-----QAQISRVLIERPSNK-SIIININAKKPNIIIGRNGSEIDKLKKAIEKMVY INIHEVRK---FNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLISVSF-PSSKIKTSILDVLQKEGYIKDYI TTQ----K---N----NISYTEVALKYS---VNG-------D---ASICEIHRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFAKINGPIPLPKKIGRFTVNRS PHVHKKSR-EQFEIRKHKRLLVIGDPNPAVVDALSKVDLAAGVDVVIELKRLLQGVVISSKADKTVTVKVERKFKHPIYK KFVKVSKKYAAHDSE--NKYQEGDKVSIIESRPISKTKTWVVVN----G------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLME---SGKSE----MIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNE-EMVGR KLGEFAPTRTFHGHG------A---DK----KIK------RK >ALPHA_Rickettsia_typhi_Wilmington Concatenation of 2 sequences MALKNFNPITPSLRELVQVDKTN-LWKG------------RP-LKSLTKGMSKTGGRNQQGRITSWH-RGGGHKKL---- YRVIDFK-R--KK-IDIFAVVERIEYDPNRTAFIALIKYD-DGEYSYILAPQKLSIGDRVISSQ-A-AD-IKIGNCLPLK SIPIGTTLHNVEMKVGKGGQIARSAGTSVELVGK--DSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRN -RWL-----GWR-P-HVRGVAMNPIDHPHGGGEGKT----SGGRHPVTP---WGFSTKGKKTR-KNKR-TS-K-FIVKKR --------------------------------MRT---G-IIAQKIGMTSVFN-DKGE---------RISLTLVKVDGCQ VVGHK----TLA----K--HGY--NALVIGV-------KD--QVTK----------PMKQVF------------------ ---NAKISPKTKLKEFRI--------SEDNFI-----DI---AS-ILEV--D-H-FSVGQFVDITATTIGKGFAGSMKRH NFRG-LEASHGVSISHRS-HGSTGQR-QDPG-KVFKGKKMAGHMGCNQVTIQNLKIFAIDTNRK---------------- ----------LIMIQGS-IPGHKNSYLLVK--MKTKILS-LANEEV-GEITLNKDIF----AV-EFIRDDIIKQVIDWQR AKAMSGNHKTKTVSE--------VS-GTTKKPF---------KQKGTGNAR--------QGS---LR-SI----QM---- RGGGISHGPK-V-RSHAIKLPKKVRKLGLIHALSEKCAAG----------------K-LLIINSL----KLE-K------ --PKTSFII--DNKVD--T---NFSLATKNIYNTL-I---------------VPQIGANVYDIIRHEY----VLLSQEAV SFLELRFKELYKKKI----IESLKKEFSFKNQHEIPQIKKIVINMGVG-EAIADSKVINNALNDLTLISGQKPIVTLARK SIATFKLRENMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSY-KSFDGKGNFTFGLKEQIVFPEIN-----YDKI DTIRGMDITIVTS-----------------------AKTDQESKFLLSGFNLPFMSRVG-K--LPITIPEGVKVG-L--- -N-D--L-EVKISGPKGELSKTF--KG-N--IAIIMEE-NK--LVV----K-P-LAVNKNAR-SMWGTARSIIYNMVTGV KEGFKLKLEINGVGY--RAMVKG-KY--LNLM--LAKSHNTKIEI-P-S-NIKIDLP--K-QNIILLEG-IDKEKLGQFA SIIIKQR------PPEPY---KGKGIKFENKFIQRKEGK----------MIQMQSILEVADNSGAKKVMCIKVLG-SHHM M--AKLGDVIVVSIKEAIPG-G-------KVKKGDVYKGVIVRTKTGVVRSDGSTIKFDKNALVLLN-KQDE-PIGTRVF GPVTRELR-AKKYVRIMSLAEEVLMK-L--NELYNNIGA-KKNKKRIA-RGIGSGK-GKTAGRGIKGQKSRSGVA----- -IKGF-E-GGQTPMIKRLPK-RG--FKCINIYNIITKEKLIEI-GLINVK---------LLSICSDD-F-A-S-P-LSL- KLDAYSSKAKYLIEKAGGQL-K---AHK--GRV---MSKA-KAGMTLAFG----------SFGLKSI--DGWRVTARQIE AGRKAATRCM------KRQGRLWIRIFPDVPVSKKPAEVRMGKGK---------GAPEFFAVRVSP-GRIMFEI--EG-- VEENIALRALELASAKLPVRTRI-VAKLKFEKRKSRIRHKI---SRTSNRVRLSVFKSGRHIYAQIIDD---S--KSITI ASASTL-DKTI-KKIK----KSH-CNVENAIKIGREIAKK--ANSAG-IKEVVFDRGGYKYH--GIIKALADAAREK-IT F-------------------------------------------------------------KNF-ATAKAKSIRVSPRK LNLVASFIRNMKVSEALIQLTFS---------------------------------PKRIAKIVKDCLRSAVAN----A- ENNL-GLDIDRLIITKATVGKSVVMKRIMPRAKGRATRINKFFSNLDITVTEKLKVKKGDEVIVVTGK------YK-GKK GKVLKVFIDEN--TVI--VSGVNLVKKHTK----PN--KM--SE-GGIITKESPIHISNVA-HIDPKT-------GN--P --TKVAFKF---LE--------DGKVR---IAKKSG---EII--MGQKVCAHGFRVGPTLI-KDWDSILYA------E-K H--YKTLFIQDLKIRDLI--NKWFN-----QAQISRVLIERPSNK-SIIININAKKPNIIIGKNGSEIDKLKKAIENMVY INIHEVRK---FNIDAAIVAQTIAAQLEKRVSFRKAMKTAIQASFKQ-GGQGIRVSCSGRLGGAEIARTEWYIEGRMPL- -HTLRADIDYSTAEAITTYGVIGVKVWIYMSMTDNVADMLTRIRNAYKSKLINVSF-PSSKIKNSILDVLQKEGYIKDYV ITQ----K---N----NISYTKVALKYS---ING-------E---ASICEIRRVSKPGKRVYSAIKDLKGYYNNMGIYIL STPYGVMSDREAHIKNVGGEVICKVF-MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFATINGPIPLPRKIERFTVNRS PHVHKKSR-EQFEIRKHKRLLVIDDPNPAVVDALSKVDLAAGVDVVIELKRVLQGVVISSKTDKTVTVKVERKFKHPIYK KFVKVSKKYAAHDIE--NKYREGDKVSIVESRPISKTKTWVVVNVE---------------------------------- -MARSI-WKGPFVDG-YLIKKVQKLMK---SGKSE----MIKTWSRRSTILPLFVGFTFSVHNGNKFIPVYINE-EMVGR KLGEFAPTRTFHGHG------A---DK----KVK------RK >ALPHA_Roseobacter_denitrificans_OCh_114 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKALTEGLSKHGGRNNTGRITMRR-KGGGAKRL---- YRIVDFK-R--NK-MDVAATVERIEYDPNRTAFIALVKYE-DGEQAYILAPQRLAVGDTVVASQ-K-AD-IKPGNAMPFS GMPIGTIIHNIEMKPGKGGQIARAAGTYAQFVGR--DGGYAQIRLSSGELRLVRQECMATVGAVSNPDNSNQNYGKAGRM -RHK-----GVR-P-SVRGVVMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGAKTR-NKKKASS-Q-LIIRSR --------------------------------LRS---G-VIAKKVGMTRLFM-EDGK---------QIPVTVLQLDKLQ VVAQR----TSE----K--DGY--SAVQLGA-------GT--ATSQ----------AMRGHF------------------ ---AAKVEPKRKVAEFRV--------DPENLI-----GV---GE-EITA--N-H-YFEGQFVDVAGTSIGKGFAGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHMGAARVTTQNLQVVRTDANRG---------------- ----------LIMVKGA-VPGSKGGWVTVK--MKLDVIK-LDGAKA-GSVDLDEALF----GL-EP-RADILHRVVRWQR NNAQAGTHKVKTRSE--------VN-YSTKKIY---------RQKGTGGAR--------HGA---RS-AP----IF---- RGGGVYKGPK-V-RSHGHELTKKFRKLGLCHALSAKMKAG----------------E-LVIIDEV----SSD-------- --GKTALII--DGATN--E---TFAQAARNIDGLD-I---------------LPTMGANVYDILKRDT----LVITKAGV EALEPRLKAVYRDTI----RAALKEEFGYKNDMQIPRLDKIVLNIGCGAEAVRDSKKAKSAQADLTLIAGQKAMTTTAKK SIAGFRVREEMPLGAKVTLRGDRMYEFLDRLITIAMPRIRDFRGISG-KSFDGRGNYAMGLKEHLVFPEID-----FDKI DENWGMDIVIATT-----------------------AQTDAEAKSLLKAFNMPFMSRIG-K--KPVDLPAGVSAS-V--- -S-G--Q-TIEIKGPKGTRAFKA--TD-D--VTLTVED-NV--VTV----T-P--RGKKRAR-QQWGMSRTMVANLVTGV SEGFKKELEIQGVGY--RAAMTG-NT--LKLN--LGLSHDVDYTP-P-A-GVTVTAP--K-QTEIVVEG-IDEQLVGQVA ANIRQWR------KPEPY---KGKGIRYKGEFVFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SKRK Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILN-NNNE-PIGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--HELSDNDGA-AKKRKRVG-RGPGSGT-GKMGGRGIKGQKSRSGVA----- -IKGY-E-GGQMPLYQRLPK-RG--FNKVNLGLIITEDALIAS-GLVRIR---------VLA--KGD-V-T-G-K-LNI- EVTGASKSAIEAVAKAGGSL-K---QFK--GSI---KGLA-KGGSDLNFG----------TYGLKAI--EPERITARQIE AARRAMTRHM------KRQGRVWIRIFPDVPVTAKPIEVRMGKGK---------GSVDRWAAKVKP-GRVMFEI--DG-- VNDDVAREALRLAAMKLPIKTRV-VKRQLFIKRRLRVRNKL--RKVNAGRVRLSVHRSNKNISVQLIDD---V--AGKTL ASASTL-EKDL-------GVVGK-NNIEAAAKVGAAIAER--AKKAG-VSEAYFDRGGFLFH--GKVKAVAEAAREGGLK I-------------------------------------------------------------DNE-AMAKLRMLRTSPQK LNLVAGLIRGKKVEQALTDLTFS---------------------------------KKRIAHDVKKCLQSAIAN----G- ENNH-NLDVDELIVAEAYVGKNLTMKRGRPRARGRFGKIIKPFSEITIVVRQAAKLKKGDKVIVLAGK------DK-GKT GSISSVDPKSG--KAI--VDGINIAIRATR--------QSQTEQ-GGRIPKAMPIDLSNLA-YVDAN--------GK--A --TRVGFKM----E--------GDKVR---FAKTTG---DVI--MGNKVNPIGMRLQ--VN-RTWDSRWYA------DTK D--YGDLLLEDLAIRDFI--KKECH-----QAGVARVIIERPH-K-KCRVTIHTARPGVIIGKKGADIEGLRQKIAKMLH LNIVEVRK---PELDAALVGESIAQQLERRVSFRRAMKRAVQNAMRM-GALGIRVNVAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYAHVEAATAYGIIGIKTWIF--MNDPIADMLTRIRNSQLRGKSTVIT-PASKLRAWVLDVLADEGYIRGYE KIT--GAD--------GHPAIEISLKYY----EG-------E---PVIRELKRVSKPGRRVYMGVNDIPVVRQGLGVSIV STPKGVMSDQAARSANVGGEVLCTVFAQSQNIRIRLKAFDYRVLDTSTQEIVNTAKRTGASVRGPIPLPNKIEKFTVLRG PHVDKKSR-DQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILSGVVTSDANDQTVSVSVERRFTHPVLK KTIRKSKKYRAHDEN--NTFKKGDAVRIVECAPKSKTKRWEVLQ--AAE------------------------------- -MSRSV-WKGPFVDS-YVLKKAEASRE---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGRKHIPVNITE-DMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Silicibacter_pomeroyi_DSS-3 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKSLTEGLTKSGGRNNTGRITSRR-RGGGAKRL---- YRIVDFK-R--NK-FDVAATVERIEYDPNRTAFIALIKYE-DGEQAYILAPQRLAVGDKVVASA-K-AD-IKPGNAMPFS GMPIGTIVHNIEMKPGKGGQIARAAGTYAQFVGR--DGGYAQIRLSSGELRMVRQECMATVGAVSNPDNSNQNYGKAGRM -RHK-----GIR-P-SVRGVAMNPIDHPHGGGEGRT----SGGRTPVTP---WGKDTKGTRTR-NKNKASQ-K-LIIRSR --------------------------------MRS---G-IIAKKVGMTRLFM-EDGK---------QIPVTVLQLDNLQ VVAQR----TTE----K--DGY--TAVQLGA-------GT--PVSK----------AMRGHF------------------ ---AQKVEPKRKLAEFRV--------SEDALI-----EV---GA-EISA--E-H-FLTGQKVDVSGTSIGKGFAGAMKRH NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-RVFKGKKMAGHMGAARVTTQNLEVVKTDAERG---------------- ----------LVFIKGA-VPGPKSGWVTVK--MKLDVIK-LDGTKA-GNIDLDEALF----GL-EP-RADILHRVVRWQR NNAQAGTHKVLTKSE--------VS-YSTKKIY---------RQKGTGGAR--------HGS---RK-SP----TF---- RHGGVYKGPT-P-RSHGHDLTKKFRKLGLRHALSAKAKAG----------------E-LVVIENA----EAE-------- --GKTALVI--DGAAN--E---GFARAARNIEGLD-I---------------LPSMGANVYDILKRDT----LVLTKAAV EALEPRLKAQYAETI----RAALKEEFGYKNDMMIPKLEKIVLNIGCGAEAVKDSKKAKSAQEDLSKIAGQKAITTTAKK SIAGFRVREDMPMGAKVTLRGERMYEFLDRLITIAMPRIRDFRGVKP--SFDGRGNFAMGIKEHIVFPEID-----FDKV DEVWGMDIVIATT-----------------------AKTDAEAKSLLKHFNMPFMSRIG-K--KPVELPSGVSAA-V--- -S-G--Q-TIEVKGPKGARSFTA--TD-D--VTITVDG-NV--VSI----T-P--RGMKRAR-QQWGMSRTMVANLVAGV TEGFKKELEITGVGY--RANAQG-NT--LKLN--LGYSHDVDFTV-P-A-GVTVSTP--K-QTEIVVEG-IDQQQVGEVA AKIREWR------SPEPY---KGKGIRYKGEFIFRKDGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SKRK Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILN-NNNE-PVGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--HELSDNPGA-TKKRMRIG-RGPGSGK-GKMGGRGIKGQKSRSGVA----- -INGY-E-GGQMPLYQRLPK-RG--FNKVNLGLIITEDALVAS-GLVRIR---------VLA--KGD-F-N-A-K-LNI- EVTGASKSAVEAVEKAGGSL-K---MFK--GRI---HGLA-KGGSDLNFG----------TYGLKAL--EPERVTARQIE AARRAMTRHM------KRQGRVWIRIFPDTPVTSKPTEVRMGKGK---------GSVDYWACKVKP-GRVMFEI--DG-- VNDEIAREALRLAAMKLPIKTRV-VKRTLFLKRRLRVRNKL--RKVNAGRLRLSVHRSNKNISAQLIDD---V--RGVTL AAASTM-EKDL-------GVVGK-NNVEAAKKVGAAIAER--AKKAG-VEEAYFDRGGFLFH--GKVKALADAAREGGLK I-------------------------------------------------------------ENE-AMAKLRMLRTSPQK LNLVAAMIRGKKVGQALTDLTFS---------------------------------NKRIAQDVKKCLQSAIAN----A- ENNH-NLDVDELIVAEAWVGKNLVMKRGRPRARGRFGKIMKPFSELTITVRQAAKLRKGDKVVVLAGK------DK-GKE GTITSVDPKAG--KAV--VDGVNIAIRHTR--------QTQTSQ-GGRLPKALPIDLSNLA-LLDKN--------GK--A --TRVGFRM----E--------GDKVR---FAKTTG---DVI--MGHKVNPIGMRLQ--VN-RTWDSRWYA------DTK D--YGNLLLEDLAIREFI--KEECK-----QAGVARVIIERPH-K-KCRVTIHTARPGVIIGKKGADIETLRKKLANMLH LNIVEVRK---PEMDAQLVAESIAQQLERRVSFRRAMKRAVQNSMRM-GALGIRVNVAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYALAEASTPYGIIGIKVWIF--MNDPIGDMLTRIRNAQLRGKSTVST-PGSKLRAWVLDVLADEGYIRGYE KST----D--VN----GHPTLNIELKYY----EG-------E---PVIRELKRVSKPGRRVYMGVKDIPSVRQGLGVSIV STPKGVMSDANARSNNVGGEVLCTVFMQSQNIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHVDKKSR-DQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGTVTSDANAQTVTVLVERRFTHPVLK KTIRKSKKYRAHDEK--NAFKVGDTVRIIECAPKSKTKRWEVLE------------------------------------ -MSRSV-WKGPFVDA-YVLKKAAAVRE---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGQKHIPVNVTE-DMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Silicibacter_sp_TM1040 Concatenation of 2 sequences MALKSYKPTTPGQRGLVLIDRSE-LWKG------------RP-VKSLTEGLTKSGGRNNTGRITSRR-RGGGAKRL---- YRIVDFK-R--NK-FDVAATVERIEYDPNRTAFIALVKYE-DGEQAYILAPQRLAVGDKVIASA-K-AD-IKPGNAMPFS GMPIGTIVHNIEMKPGKGGQIARAAGTYAQFVGR--DGGYAQIRLSSGELRLVRQECMATVGAVSNPDNSNQNYGKAGRM -RHK-----GKR-P-SVRGVVMNPIDHPHGGGEGRT----SGGRHPVTP---WGKPTKGKRTR-NTNKASQ-K-LIIRSR --------------------------------MRS---G-IIAKKVGMTRLFM-EDGK---------QIPVTVLSLDGLQ VVAQR----TED----K--DGY--TAVQLGA-------GS--AVSK----------AMRGHFA----------------- ---SK-VEPKRKLVEFRV--------PADGLI-----EV---GA-EISA--E-H-FLEGQKVDVTGTSIGKGFAGAMKRW NFGG-LRASHGVSISHRS-HGSTGQC-QDPG-KVFKGKKMAGHMGAARVTTQNLEVVKTDADRG---------------- ----------LVFIKGA-VPGPKSGWVTVK--MKLDVIK-LDGGKA-GDIELSEDLF----GL-EP-RADILHRVVRWQR NNAQAGTHKVKTRSE--------TS-YSTKKIY---------RQKGTGGAR--------HGD---RN-AP----IF---- RKGGIYKGPT-P-RSHGHDLTKKFRKLGLRHALSAKAKAG----------------E-LVVIENA----EAE-------- --GKTALVI--DGAAN--E---GFARAAKNIEGLD-I---------------LPSMGANVYDILKRDT----LVLTKSAV EALEPRLKTLYKDTI----RGALKEEFGYKNEMQIPKLDKIVLNIGCGRAAVKDSKKAKSAQEDLTKIAGQKALTTVAKN SIAGFRVREGMPMGAKVTLRGERMYEFLDRLITIAMPRIRDFRGVSG-TSFDGRGNYALGLKEHIVFPEID-----FDKI DEAWGMDIVIATT-----------------------ANTDAEAKALLKAFNMPFMSRIG-K--KPVELPSGVSAS-L--- -S-G--Q-TIEVKGPKGAQTFTA--TD-D--VTLTVED-NV--VKV----E-P--RGKKRAR-QQWGMSRTMVANMVQGV TQGFKKELEIQGVGY--RAQMQG-NT--LKLN--LGYSHDVDFTA-P-E-GVTITAP--K-QTEIVVEG-ADAQAVGEVA AKIRDWR------RPEPY---KGKGIRYKGEFIFRKEGK----------MIQMQTNLDVADNSGARRVQCIKVLG-SKRK Y--ASVGDIIVVSVKEAIPR-G-------RVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILN-NNNE-PVGTRIF GPVVRELR-AKNFMKIISLAPEVLMK-L--NELRDNPGA-SPKRTRVG-RGPGSGK-GKMGGRGIKGQKSRSGVA----- -INGY-E-GGQMPLYQRLPK-RG--FNKVNLGLIITEDSLVAS-GLVRIR---------VLA--KGE-F-T-A-K-ATI- AVTGASKSAVEAVSKAGGAL-K---MHK--GRI---KGLA-KGGSDLNFG----------TYGLKAV--TPERVTARQIE AARRAMTRHM------KRQGRVWIRIFPDTPVTSKPVEVRMGKGK---------GSVDFWACKVKP-GRVMFEI--DG-- VNEDIAREALRLAAMKLPVQTRI-VKRTLFLKRRLRVRNKL--RKVNAGRLRLSVHRSNKNISVQLIDD---V--KGVTL AAASTL-EKDL-------GFVGK-NNIEAATKVGSVIAER--AKAAG-VTEAYFDRGGFLYH--GKVKALADAAREGGLK I-------------------------------------------------------------DNE-AMAKVRMLRTSPQK LNLVAQMIRGKKVDKALTDLTFS---------------------------------NKRIAQDVKKCLQSAIAN----A- ENNH-NLDVDELIVAEAWVGKNLTMKRGRPRARGRFGKILKPFAEITIKVRQAAKLRKGDKVVVLAGR------DK-GKE GTIASVDPKAG--KAV--VDGVNMAIRHTR--------QTQTSQ-GGRLPKALPIDLSNLA-LLDSN--------GK--A --TRVGFRE----E--------DGKVR---FAKTTG---ETV--MGHKVNPVGMRLQ--IN-RTWDSRWYA------DTK D--YGDLLLEDIKIREFI--KEECK-----QAGVARVIIERPH-K-KCRVTIHTARPGVIIGKKGADIEVLRKKIASMLH LNIVEVRK---PELDAQLVGESIAQQLERRVSFRRAMKRAVQNAMRM-GALGIRVNVAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYAHSEASTPYGIIGIKVWIF--MNDPIGDMLTRIRNSQMRGKSTVMT-PASKLRAWVLDVLQSEGYIRGYE SAT----D---E---RGHPALEISLKYY----EG-------E---PVIRELKRVSKPGRRVYMGVNDIPSVRQGLGVSIV STPKGVMSDANARAANVGGEVLCTVFMQSQNIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRG PHVDKKSR-DQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGVVTSDANAQTVTVSVERRFTHPVLK KTIRKSKKYRAHDEK--NAFKVGDTVRIIECAPKSKTKRWEVLE------------------------------------ -MTRSV-WKGPFVDA-YVLKKAEAARD---SGRNE----VIKIWSRRSTILPQFVGLTFGVYNGQKHIPVNVTE-DMIGQ KFGEYSPTRTYYGHA------A---DK----KAK------RK >ALPHA_Sinorhizobium_medicae_WSM419 Concatenation of 2 sequences MALKSFNPTTPSQRQLVIVSRAG-LYKG------------KP-VKTLTEGLSSKGGRNNLGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEGTVERLEYDPNRTAFIALVNYA-DGEQAYILAPQRLAVGDKVIASEKA-VD-VKPGNAMPLQ FIPVGSIIHNVEMKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHGNINDGKAGRS -RWR-----GKR-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-FIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HIPVTVLRLENCQ VVAQR----TEE----K--NGY--TAVQLGA-------GR--STPK----------AMRGHFA----------------- ---AS-VEPKAKLVEFRV--------SADNLI-----DI---GS-ELTA--G-H-FVAGQLVDVTGTTIGKGFAGAIKRH NFGG-LRATHGVSVSHRS-HGSTGSN-QDPG-RVWKGKRMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGSWIVVR--MDLTVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDIIARVVRWQL AKRQQGTHKAKGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHDLPKKVRALGLRHALSAKLKAE----------------E-IIIVDDL----VAN-E------ --AKTKLII--GGAEE--G---NFKLAAQNIPNVD-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALEPRLKKEYVERI----RKAIQEQFSYANEMQIPRLDKIVINMGVG-EATGDSKKPTVAAADLAAIAGQKPVITRARN SIAGFKLREGMPIGAKVTLRGVRMYEFLDRLINIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATNDDEARALLKEFNFPFMSRIG-K--KPVQVPAGVTAN-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--VSVKLEN-NT--VVV----Q-P-VNESKDAR-AKWGMSRTMIENILKGV KDGYERKLEINGVGY--RASMQG-KN--LQLA--LGFSHDVVYQT-P-E-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAEERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGA-TKNRKRLG-RGIGSGS-GKTAGRGVKGQKARSGVS----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLGRIVDAAALKAA-GVIRVR---------VLA--DGE-L-K-A-K-VSL- EVAGASKPAIEKIEKAGGSI-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRHM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VSEELAREALRLGAAKLSVKTRF-VRKDTLVRRASRVRRQI--KAVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTI ASASTL-DTDL-RFSL----KTG-ADTEAATAVGKLLAER--ASKAG-VKDVVFDRGAFIYH--GRIKALAEAAREGGLN F-------------------------------------------------------------DNE-AQAVARTIRVSPQK LNLVAALIRGKKVDRALAELEFS---------------------------------RKRIAGTVRKTLESAIAN----A- ENNH-DLDVDSLIVAEAFVGKSIVMKRFHARGRGRASRVEKPFAHLTIVVREMQKIRKGDKVVVLTGK------DK-GRT GEVIQVMPKED--RAV--VRGVNVVKRHQR----QT--QN---QEAGIITKEAPIHLSNIA-IADPKD-------GK--P --TRVGFKI----D--------GDKVR---VAKRSG---DVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKIRAYL--MEELK-----AAGIAKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRKKLSEMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGVKVWIFMAMTDPLGDMLTRIRNGAARRKSSVST-PASKLRARVLDVLQAEGYIRGYS EVE--FGN--------GKAELSIELKYY----EG-------A---SVIREIARVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSVFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGTVVSDKNDKTVVVRVERRFAHPILQ KTVRRSKKYKAHDES--NQFKVGDLVSIEECAPISKDKRWTVVS--AQS------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Sinorhizobium_meliloti_1021 Concatenation of 2 sequences MALKSFNPTTPSQRQLVIVSRAG-LYKG------------KP-VKTLTEGLSSKGGRNNLGRITVRF-QGGGHKRT---- YRLVDFK-RR--K-FDVEGTVERLEYDPNRTAFIALVNYA-DGEQAYILAPQRLAVGDKVIASEKA-VD-VKPGNAMPLQ FIPVGSIIHNVEMKPGKGGQIARSAGTYAQLVGR--DQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHGNINDGKAGRS -RWR-----GKR-P-HVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGKRTR-S-NKSTD-K-FIMRSR --------------------------------MRS---G-VIAQKVGMTRVYN-DAGE---------HIPVTVLRLENCQ VVSHR----TEE----K--NGY--TAVQLGA-------GR--STPK----------AMRGHFA----------------- ---AS-VEPKAKLVEFRV--------SADNLI-----DI---GA-ELTA--G-H-FVAGQLVDVTGTTIGKGFAGAIKRH NFGG-LRATHGVSVSHRS-HGSTGSN-QDPG-RVWKGKRMAGHMGQTRVTTQNLEVVSTDEDRG---------------- ----------LILVKGA-VPGSKGSWIVVR--MDLTVKT-LEGKDA-GKVSLSDAIF----GL-EP-REDIIARVVRWQL AKRQQGTHKSKGRAE--------VS-RTGAKMY---------KQKGTGRAR--------HHS---AR-AP----QF---- RGGGKAHGPV-V-RSHAHDLPKKIRALGLRHALSAKLKAE----------------D-IIVIDDL----VAN-E------ --AKTKLII--GGAEE--G---NFKLAAQNIPNVD-V---------------LPVQGINVYDILRRGK----LVLSKAAV EALESRLKKEYVERI----RKAMQEQFSYANEMQIPRLDKIVINMGVG-EATGDSKKPTVAAADLAAIAGQKPVITRARN SIAGFKLREGMPIGAKVTLRGVRMYDFLDRLINIALPRVRDFRGLNP-KSFDGRGNFAMGIKEHIVFPEIN-----YDKV DQMWGMDIIVCTT-----------------------ATNDDEARALLKEFNFPFMSRIG-K--KPVQVPAGVTAN-V--- -D-G--Q-KVTAKGPKGELFFVA--ND-E--VSVKLEN-NT--VVV----Q-P-LNESKDAR-AKWGMSRTMIENILKGV KDGYERKLEINGVGY--RASMQG-KN--LQLA--LGFSHDVVYQT-P-E-GITIAVP--K-PTEIVVSG-INKQQVGQVA AEIREYR------GPEPY---KGKGVKYAEERIVRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--ASIGDIIVVSIKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRADGSVIRFDTNAAVLID-NKKE-PIGTRIF GPVPRELR-AKNHMKIISLAPEVLMK-L--NEIKDNEGA-TKNRKRLG-RGIGSGS-GKTAGRGVKGQKARSGVA----- -INGF-E-GGQMPIYRRLPK-RG--FNNVSLGRIVDAAALKAA-GVIRVR---------VLA--DGE-L-K-A-K-VSL- EVAGASKPAIEKIEKAGGSI-K---QFK--GRI---KGVA-KGGSDLAFG----------EFGLKAQ--EPNRVNAREIE AARRAITRHM------KRAGRVWIRVFPDVPVTAKPTEVRMGKGK---------GSVEYWACKVKP-GRMMFEI--DG-- VNEELAREALRLGAAKLSVKTRF-VRKDTLVRRASRVRRQI--KAVANGRPRLSVHRSSKNIYAQIIDD---V--AGKTI ASASTL-DTDL-RSSL----KTG-ADTEAATAVGKLLAER--ASKAG-IKDVVFDRGAFIYH--GRIKALAEAAREGGLN F-------------------------------------------------------------DNE-AQAVARTIRVSPQK LNLVAALIRGKKVDRALAELEFS---------------------------------RKRIAGTVKKTLESAIAN----A- ENNH-DLDVDSLIVAEAFVGKSIVMKRFHARGRGRASRVEKPFAHLTIVVREMQKIRKGDKVVVLTGK------DK-GRT GEVIQVMPKED--RAL--VRGVNVVKRHQR----QT--QN--QE-AGIITKEASIHLSNIA-IADPKD-------GK--P --TRVGFKI-------------DGKVR---VAKRSG---DVI--MGQKINPIGFRLG--IN-RTWDSRWFA------DNA E--YGQLLHEDLKIRAYL--MEELK-----SAGIAKVVIERPH-K-KCRVTIHSARPGLIIGKKGADIEKLRKKLSEMTH LNIVEVRK---PEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIKITCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGTAEAETAFGICGVKVWIFMAMTDPLGDMLTRIRNGAARRKSSVST-PASKLRARVLDVLQAEGYIRGYS EVE--FGN--------GKAELNIELKYY----EG-------A---SVIREIARVSKPGRRVYVSVKSIPQVANGLGITIL STPKGVMADHQAREQNVGGEVLCSIFMNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRS PHVDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRILQGTVVSDKNDKTVVVRVERRFAHPILQ KTVRRSKKYKAHDEN--NQFKVGDLVSIEECAPISKDKRWTVVS--AQS------------------------------- -MARSV-WKGPFVDG-YLLKKAEKVRE---GGRNE----VIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSE-EMVGH KFGEFAPTRTYYGHG------A---DK----KAK------RK >ALPHA_Sphingomonas_wittichii_RW1 Concatenation of 2 sequences MALKHYNPTSPARRGLILVDKSG-LHKG------------KP-VKALTEGKRKSGGRNNQGHATARG-IAGGHKQK---- YRIVDFK-RR--K-WDQPATVERLEYDPNRSAFIALVKYE-DGELAYILAPQRLAAGDVVLAAK-K-TD-TKPGNAMEIG QAPVGTIVHNVEMKPGKGGQIARAAGTYVQIVGR--DKGMVMVRLNSGEQRYIRSDCMCTVGAVSNPDNANQNLAKAGRN -RWL-----GRR-P-LTRGVAKNPVDHPHGGGEGRT-S--GGRH-PVTP---WGKPTKGARTR-H-NKATD-K-FIIRSR DRPDPRRGAGDWSPPFAAMRNPCPGGGYRKLGERIMRTG-VIAKKMGMTRLFQ-EDGR---------HVPVTVLALENVQ VVARR----EQD----R--DGY--VAVQLGA-------GS--ALTK----------PERGHFK----------------- ---AE-VEPKAFVAEFRV--------SEDGLL-----DV---GA-EISA--D-H-YVAGQFVDIQGSTQGKGFAGGMKRW GFGG-LRATHGVSVSHRS-LGSTGQR-QDPG-KVFKNKKMAGHMGDKNRTQQNLEIVQTDAERG---------------- ----------LLFVKGS-VPGSKGGWLLVK--MKVKVQT-LDAKAS-GDIELNDEVF----AV-EP-RADILARVVQWQL HNRRAPARAARERSD--------VA-RTGKKFG---------RQKGGGTAR--------HGD---RR-AP----VF---- IGGGKAHGPR-A-RVFESSLNKKVRALGLKMALSSKAKDG----------------K-LVVVDTL----ELK-D------ --AKTKLVI--DEAVD--N---GFQLASSNIHTIN-V---------------LPAIGANVYDILKHET----LVLTRAAV EKLEPRFRKLYDETI----VKAMTEKFGYKNHMEVPKITKIVLNMGVG-EATQDKKKVEQAALEMTKIAGQKAVITKAKK SIAQFKLREGMPIGAKVTLRRERMYEFLDRFVTIALPRVRDFRGLNP-KSFDGRGNYATGLKEQLIFPEIS-----YDSV DKIRGMDVIVATT-----------------------AKTDDEARELLRLFGFPFMSRIG-K--KPVSVPAGVTAA-I--- -E-G--K-TLSVKGPKGTLSISL--AD-E--VSYAIED-GS--ISV----Q-P-INETKRAR-SFWGMQRTLVQNLITGV TEGYSKTLQITGVGY--RANVQG-KN--LKLQ--LGYSHDVDFAI-P-E-GITIATP--D-QTTVQISG-IDKQKVGQVA AEIRRWR------KPEPY---KGKGIKYAGEYIFRKEGK----------MIQMQTNLDVADNSGAKRVQCIKVLG-SKRR F--ATVGDVIVVSIKEAAPR-G-------KVKKGDVHRAVIVRTAKDIHRPDGSTIRFDGNAAVLINKNSGE-PIGTRIF GPVVRELR-AKNHMKIISLAPEVLMK-L--NEIRDNQGA-RKSRVRVG-RGIGSGL-GKTGGRGQKGQKSRSGVS----- -INGF-E-GGQMPLHMRLPK-RG--FNNVNLGAIIDHAALKAA-GVARVR---------ILG--KGE-L-T-A-K-VSF- KVAGVSAGAKAAIEKAGGSV-K---AHK--GRI---HGNA-PGGASLNFG----------AFGLKAL--EPDRITARQIE AARRAITRHI------KRQGRLWIRIFPDVPVSSKPAEVRMGSGK---------GSPEFWAARVKP-GRILFEL--DG-- VPGPLARVAFERAMEKLPIKTKV-VRRRRRVRTALRARGGL--------RPRLSVHRSGRHIYAQVIDD---E--AGRTV ASASTL-DKDM-KG------KTG-ATADAAASVGKAVAER--AKAAG-VTQVVFDRGGFLFH--GRVKALADAAREGGLE F-------------------------------------------------------------EKE-ALAVATTVRGSPYK LNLVAGLIRGKKAGDALNILTFS---------------------------------KKAMAVDVRKVLASAIAN----A- ENNH-NLDVDALVVKEASVGKSIVMKRFATRGRGKSTRIIKPFARLRVVVREALKIKKGDRVVVLSGK------DK-GKT GEVTKSFPKDA--KVI--VSGVNVATRHRK----PS--QA-NPQ-GGLERVEAPLHVSKVA-IATAD--------GK--P --TRVRFEV----K--------DGKVR---VAVKTG---ETI--MGQKSNPIGMRLQ--IN-RTWDSRWYA------DGA D--YGRLLLEDLKIRKHI--MKAIP-----QAAISKVVIERPA-K-LCRISVYAARPGVIIGKKGADIEKLRRALGKMVS LNIVEIRK---PEIDSKLVAQGVADQLERRIAFRRAMKRAVQSALRL-GAEGIRITCAGRLGGAEIARTEWYREGRVPL- -HTLRANVDYAEAEAHTAYGVCGIKVWIFMALTDPLGDLLTRIRNGQRARKDSVLS-PASKLRARVLDVLQREGYIRGYS EED----L---A----GHSGLRIELKYF----EG-------Q---PAIQHVARVSKPGRRVYSGSKDLPRVRNGLGITIV STPRGVLSDAEAREQNVGGEVLAEVFMETQNIRIRLKAFDHRVLDQATGDIADTARRTGALIRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEVRTYKRLLDIVQPTPQTVDALMKLDLAAGVDVEIKLKRVLTGTVVSDKTDKTVVVKVERRVKHALYG KIIKRSKKYHAHDET--NEYREGETVRIEETAPMSKLKTWKVIERVD-T------------------------------- -MARSI-WKGPFVDL-HLLRKAEGAQD---SGARA----PIKTWSRRSTILPQFVGLTFNVYNGRKFVPVSVSE-EMVGH KLGEFAPTRYFPGHA----------DK----KGK------R- >ALPHA_Sphingopyxis_alaskensis_RB2256 Concatenation of 2 sequences MALKSYNPTSPGQRGLILVDKSA-LWKG------------KP-VKALTEGKRKTGGRNNKGHVTSRG-IAGGHKQK---- YRFIDFK-R--RK-WDVPATVERLEYDPNRTAFIALVKYE-DGELAYILAPQRLAVGDTIVAGK-K-TD-VKPGNAMELA QMPVGTIVHNIEMKPGKGGQIARSAGTYAQVVGR--DRGLVIVRLGSGEQRYIRGECMGTVGAVSNPDNQNTNLGKAGRN -RWL-----GKR-P-LTRGVAKNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGARTR-HNKS-TD-K-MIIRSR --------------------------------MRT---G-VIAKKMGMTRLFQ-DDGR---------HVPVTVLSLEGCQ VVSVR----DKE----R--DGY--VAVQLGA-------GT--AVAK----------PQRGAYK----------------- ---AE-VEPKAKLVEFRV--------ADDATL-----DV---GA-ELSA--D-H-FVAGQMVDIQGVTQGKGFAGAMKRW GFGG-MRATHGVSISHRA-HGSTGNR-QDPG-RVFKNKKMAGHMGARNRTQQNLEIVRTDAERG---------------- ----------LLFVKGS-VPGSKGGWLLVR--MKIKVQT-LDGKAG-ADIDLNDDVF----GL-DA-RADILHRVVAWQL EKRRGPARAARERSD--------VA-RTGKKFG---------RQKGGGTAR--------HGD---RR-AP----IF---- IGGGKAHGPR-A-RTFGHSLNKKIRTLGLKMALSDKAKGG----------------K-LVVIDTL----ELK-D------ --AKTKLFI--DDAVH--E---SFAMASANLIGVD-A---------------LPAIGANVYDIVRADT----LVLTRAAV EKLEPRMKKLYDDKI----VKAMTDKFGYKNAMEVPKIEKITLNMGVG-EATQDKKKVEAAAAEMELIAGQKPVVTKAKK SIAQFKLREGMPIGCKVTLRRERMYEFLDRLITIAMPRIRDFRGVSA-KSFDGRGNYAMGLKEQIIFPEIN-----YDRI DQVRGMDVIVTTT-----------------------ARTDEEARELLRLFGFPFMSRIG-K--KAVEIPSGVTAA-I--- -D-G--G-QLSVKGPKGTLAMSL--SD-N--IKYEVGD-GS--ISV----Q-P-ANDSREAR-AFWGMQRTLVQNLVTGV TEGFTKVLEITGVGY--RANAQG-KN--LKLQ--LGYSHDVDFAV-P-D-GIEIKTP--D-NTTIEISG-IDKQQVGQVA AEIRRWR------KPEPY---KGKGIKYRGEYIFRKEGK----------MIQMQSQLEVADNSGAKRVQCIKVLG-SKRR T--AGVGDVIVVSIKEAQPR-G-------KVKKGDVHRAVIVRTAKDVRRADGSVIRFDSNAAVLVN-KNEE-PIGTRIF GPVVRELR-GRGYMKIISLAPEVLIK-L--NELRDNNGA-RKGRMRVG-RGIGSGK-GKTAGRGQKGQKARSGVA----- -INGF-E-GGQMPLHMRIPK-RG--FNNVNLGMVIDHAALKAA-GVARVR---------LLA--KGE-L-T-A-K-VTF- AVAGASKGAIEAVEKAGGKV-K---AFK--GRI---HGNA-KGGTSLNFG----------SYGLKAM--EPERITARQIE AARRAISRAI------KRQGRLWIRIFPDVPVSSKPAEVRMGKGK---------GSPEYWAARVKP-GRILFEL--DG-- VPGPVAALAFERAAMKLPIKTKV-IHLTQFEKRRQRVRTAL--RQRAAGRPRLSVHRSGRHIYAQLIDD---A--AGTTL AAASTL-DKDV-RG------KTG-ATTAAAADVGKRLAAA--AKKAG-VTQVVFDRGGFLFH--GRIKALADAAREGGLE F-------------------------------------------------------------DNE-ALSVGTQIRGSAQK LNLVAALIRGRKVEDAMNVLAFS---------------------------------KKAMAVDVRKVLASAVAN----A- ENNH-NLDVDALVVKEASVGKSLSMKRWHARGRGKSTRIVKPFSRIRIVVREANKIKKGDTVVVLSGK------DK-GKT GEVTQALPKDG--KVV--VAGVNVITRHRK----PT--QQ-NPQ-GGLERKEAPLFASKVA-LADPKT-------GK--P --TRVRFET----R--------DGKVR---VAVKSG---ETI--MGQKSNPIGLRLQ--VN-RTWDSRWFA------EGE D--YGRMLVEDLKIRQYV--FKALP-----QAAISKVVIERPA-K-LCRVSIYAARPGVIIGKKGADIEKLRKKLGEMVS LNIVEIRK---PEVDAKLVAQGIADQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCAGRLGGAEIARTEWYREGRVPL- -HTLRANVDYAEAEAHTAYGVCGIKVWIFMAMTDPLGDMLTRIRNGQQAKKDSVLT-PASTLRVRVLDVLQREGYIRGYS EEA-LG-A-K-G----QHKGIRIELKYF----EG-------Q---PAIRHVARVSKPGRRVYSGSKELPIVRNGLGITIV STPRGVLSDAEAREQNVGGEVLAEVFMETQNIRIRLKAFDHRVLDQATTDIADTARRTGALIRGPIPLPTRIEKFTVNRG PHIDKKSR-EQFEVRTHKRLLDIVQPTPQTVDALMKLDLAAGVNVEIKLKRILTGTVVSDKGDKTVVVKVERKVKHPLYG KIIRRSKKYHAHDED--NAIKAGETVRIEETKPISKLKTWKVLDKVETS------------------------------- -MARSV-WKGPFVDL-HLLKKAETAQE---GGSTA----PIKTWSRRSTILPQFVGLTFNVYNGRKFVPVSVNE-DMVGM KLGEFAPTRFFPGHA------A---DK----KGK-------R >ALPHA_Wolbachia_endosymbiont_of_Drosophila_melanogaster Concatenation of 2 sequences MGMKFFNPVTPSSRGTVLVSKVG-LSKD------------EP-EKSLTSGKKSSGGRNNHGRITTRH-RGGGHKKK---- YRVIDFK-R--NR-SGQ-GIVEKIEYDPNRSGFLALISYKEDDIKSYILAPQGMKPGDVVTAGN-D-AD-ILPGNCLLLK HIPVGSFVHNVELKPGNGAAIARAAGCYAQIVGR--DGQYVLLRLRSGQIRLILSSCKATIGVVSNPDHKNRKLGKAGRS -RWL-----GIR-P-TVRGIAMNPVDHPHGGGEGKT----SGGRHPVTP---WGVATKGKKTR-RRNKSSD-K-YIKQLK --------------------------------RRI---G-LLMMNIGHTAMY--SDNS---------RMAVTLLHLSETH IIDIK----GQD----K--CGY--NSVILGT-------GD---IAK----------PQLEYLK----------------- ---KG-INNKCKLYESRL--------NDLSGI-----EC---GK-KVGI--N-H-FVVGQYLDITGYSIGKGFAGVMKRH NFSG-LRASHGVSIAHRS-QGSTGQC-QDPG-RVFKGKKMAGHLGNSRITAQNMKILSIDHENS---------------- ----------IIAVKGNNVPGFKNSYVFVR--MECNLVN-LSNDNV-GAAQLNPLIF----SA-KQ-KLSILHDIVRWQL AKRRAGTHKTKGISD--------VS-GTTAKPY---------GQKRTGRAR--------QGS---LR-SP----QF---- RGGGIIFGPV-V-RSHTYSLNKKVRKFGLKIALSLKYLNN----------------Q-VIILDNL----NID-V------ --KKTSLIV---GDYG--D---DLLRAAKNLHYVD-L---------------IKPIGLNVFDILNHEC----VMLTKDTL KHLE-MFKELYKDSI----VKSLKDKFNYGNIMQVPKLVKVCINMGVG-DAATDSKAINEPLDSLYLIAGQKPLSTFAKK SISGFKIRKGATVGCKVTLRRDKMYEFLERLIYIALPREKDFRGFSV-KQFDGNGNFSFGIKEHISFLEID-----YDKI SKIRGMDINIITS-----------------------AVSDKEAKELLLALKFPFMSRIG-A--APINIPAGVSVE-Y--- ---N-NG-SMLIKSAKAEKEVSL--IR-D--VVCQIID-NQ--LLLSVDQD-K--DNYDKIK-PMWGTYRSNINNIINGM VDGFSVNLEINGVGY--KAECDG-KY--LTLY--LGYSHNVKYKV-P-K-DVEIKCI--K-PTHLIVSG-MDKQKVYMVA SDICKIR------KYDPY---KGKGVVIKGKFMLRKVVS----------MIQKNTLLEVADNSGARAVLCIGLL---GRK S--ASIGDTVIVSTKSITPR-G-------KVEKGKVYRAVVVRVKSPIRKSDGSVIRFSSNAVVLIN-DQGE-PLGTRVF GPV-KKLS-SGSFMKIMSLAVEVLVK-L--NSIFTKLSK-KKKPKLLG-RGIGCGK-GKTSGRGHKGQKARSGVS----- -INGF-E-GGQQSIYTRLPK-RG--FKPINVGDIIDKERLYKL-GFIKIK---------LLN--KGK-L-S-E-K-FVF- HVDFASEAAKKSVASVGGSV-K---VFK--GRI---KGNT-KGGSTLSFG----------DYGLKAM--EAGRIQSKHIE TARRVISRTL------KRSGKVWIRIFPDTPVSKKPADVRMGKGK---------GSVEFWVFKAKP-GRMLFEI--SS-D VPMHLARLALEKATAKLPMKCKF-VFLSNSEKRKLRNRAKL---DKSAERLRISIFKSNRHFYVQLIND---V--KGITL TSASTL-DAKI-KDVC----KGK-VNAETIKQVSSLMVERLSGMKLE--QQLTFDRGAYKYT--GLVSQFAEALRSSGFE F-------------------------------------------------------------DVI-VKAGSRVLKSTPRK LNLVAGLVRNKKVSFATVQLRFC---------------------------------EKKAAGLIRKVLNSAIAN------ AQNY-GLDIDNLYIKEILIGKSLTLRRVCPKAMGRANRVSKRYSNITVKLGESAKIKSGDDVIVLTGK------DK-GKI GKVIKVIARDAKKKVI--VSGVNVHKRHTK----PK--AG--SS-GGILNKELAIDISNVA-TLDPKY-------KT--P --TRVGFKV----I--------DGKVR---FAKVSG---EVI--MG-NVNPKGFRLK--II-NTWSSIWYA------E-K G--YKQGLHQDLSIRSYI--NESFK-----HAGVSKVIIERTI-D-LVSVIIHSSRPGVIIGKKGSDIEKIKQKIAEKVE VNVVGVKR---SEIDAVLISNSIAQQLEKRVSFRRAMKKAIQSCLRM-GARGIKVSCSGRLGGAEIARTEWYKEGRLPL- -HTLRANIDYAFAEAKTIYGIIGVKVWVYMALSDSIGDFLTRIRNAQLAMHRATRV-LFSKMNSSILEILKEEGYILDYE KQV----V---D----NLPSFIVKLKYY----EK-------S---PVISDIVRVSKPGCRRYSKYKDISKAYNGLGIFII STPKGVMTDYNAHKLKVGGEVLCRVF-MKQDIYINIKAFDCSLLEECVRKFIDELKRSSAKLSGPIALPRKDSKFIVNRS PHVDKKSR-EQFEMRTSRRLIVLHDLTPTMMQMLTGLSFSAGVEVDLKVKKVFCGTVTKAKCDKTVKVSVLQVYKDELYK KVIKKYKKYTAHDEN--NSCKEGDKVLIQEHKPISTTKKWVIVN---SS------------------------------- -MSRSA-WKPPFCHP-SILKSVNNALN---KGFVN---MAIKVHSRASVILPNCLGLKFAVYNGKDYIPVNVNDQNMIGH KFGEFSPTRKFTGHS------G---DK----KAT------RR >ALPHA_Wolbachia_endosymbiont_TRS_of_Brugia_malayi Concatenation of 2 sequences MGIKFLNPVTPSSRGTVLVSKIG-LSRG------------KP-EKSLAFGKKSSGGRNNNGRITIRH-KGGGHKKK---- YRIIDFK-R--NR-ND-QGVVEKIEYDPNRSGFLALVSYKCDDTKSYILAPQGIKPGDIVMSGS-G-ID-ILPGNCLPLK GIPIGSFVHGVELKPGSGAVIARAAGCYAQVVGR--DGNYVLLRLRSGQVRLVLSSCKATIGVVSNPDRKNRKLGKAGRS -RWL-----GVR-P-TVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVTP---WGVATKGKKTR-KKNKFSD-K-YIKQL- --------------------------------SLLRRIG-LLMTNIGHTAIY--SNNS---------RVAVTLLHLSETY IVDVR----RQD----K--CGY--NSVILGI-------GN---IAK----------PQLEYLK----------------- ---MG-ISNRCKLYESRL--------SDLSGI-----EC---GK-KVGV--N-H-FVVGQYLDITSYSIGKGFAGVMKRH NFCG-LRASHGVSIAHRS-QGSTGQC-QDPG-RVFKGKRMAGHLGSSRVTVQNMEILSIDHGNS---------------- ----------TIVVKGNNVPGFKNSYVFVK--MECKLVN-LSNNDV-GTTQLNPLIF----SV-EQ-KLSILHDIVRWQL AKRRAGTHKVKGISD--------VS-GTTAKPY---------SQKRTGRAR--------QGS---LR-SP----QF---- RGGGVIFGPI-V-RSHAYSLNKKVRKFGLKVALSLKYLNN----------------Q-VIILNNL----NIN-V------ --KKTSLIV---GDYE--D---SLLRAARNLHYVN-L---------------IKPIGLNVFDILNHEC----IMLTSDAL RYLE-MFKELYRDSI----VKSLKDKFNYGNIMQVPKLVKVCINMGVG-GAATDNKAINEPFDDLYLIAGQKPVSTFAKK SISGFKIRKGATVGCKVTLRRDKMYEFLERLIYVALPREKDFRGFSV-KQFDGNGNFSFGIKEHISFLEID-----YDKI SKIRGMDINIVTS-----------------------AASDKEAKELLLAFKFPFMSRIG-A--APINIPAGVSVE-C--- ---N-DG-KVLIKSAKAEKELRL--CS-D--IVCQVTD-NQ--LVLSVDQG-K--DSYNEIK-PIWGTYRSNINNIINGI VNGFSVDLEINGIGY--KAECDG-KY--LTLY--LGYSHNIKYKV-P-K-DVEIKCI--K-PTHLVVNG-MDKQKVYVIA SDICKIR------KYDPY---KGKGIVIKGKFMLRKVVS----------MIQKNTLLEVADNSGAREVLCIGLL---GRK S--ASIGDTIVVSTKSVNPK-G-------KVEKGKVYRAVVVRVKNCIRKSDNSVIRFSSNAVVLVN-NQGE-PLGTRVF GPV-KKLP-SGSFMKIMSLAVEVLIK-L--NSIFTELSK-KKKPKLIG-RGIGCGK-GKTSGRGHKGQKARSGTS----- -INGF-E-GGQQSIYTRLPK-RG--FNPINVGDVIDKEILHKL-GFIKIK---------LLN--KGK-L-N-E-R-CVF- HVDFASEAAKKSVTSIGGSV-K---VFK--GRI---KGNT-KGGSTLSFG----------DYGLKTI--EAGRVQSKHIE TVRRVISRTL------KRSGKIWIRIFPDTPISKKPTDVRMGKGK---------GSVEFWVFKAKP-GRVLFEI--SS-D VPMHLAKLALEKAMAKLPVKCKF-IFLSNSEKRNLRNRKKL---NSGVKRLRISIFKSNRHFYAQLIND---E--KGVTL TSVSTL-DAKI-KDVC----KRG-INTETIKQVSSLMIER--LSNMKLEQKLVFDRGAYKYT--GLVSQFAEALRSSGFK F-------------------------------------------------------------DPI-IGASSRILRSTPRK LNLVADLVRNKKVSFATVQLRFC---------------------------------EKKAAGLIGKVLNSAIAN----A- QYNY-GLDIDNLYIKEILIGKSFTLHRVCPKAMGRANRVSKHYSNITIKLRQSAKIRSGDDVIVLTGR------DR-GKI GKVIKIVTCSAKRKAV--VSGINVHKKHAK----PK--AG-S-S-GGIINKELAIDISNIA-ILDPKY-------KA--P --TRVGFKV----I--------DSKVR---FAKVSG---EVI--MGQKVNPIGFRLK--INNNTWDSVWYA------N-K D--YKEKLHQDLFIRSYI--NESFK-----HAGLSKIIIERKV-D-LLSVTIHSSRPGVIIGKKGLDIEKVKQKIAEKVE VNVVGIKR---PEIDAALISSSIAQQLEKRVSFRRAMKKAIQSCLRM-GGGGIKVGCSGRLGGAEIARTEWYKEGRLPL- -HTLRANIDYAFCEAKTIYGIIGVKVWVYMALSDSIGDFLARIRNAQLAMHKTTRV-LFSKVNSSILKILKDEGYILDYQ KEV----V---G----NIPSFVVKLKYY----ER-------S---PVISDIVRVSKPGCRCYSKYKDISKAYNGLGIFII STSKGVMTDYDAHKLKFGGEILCRVFEVEQVAYIISRAFDCLKLEKYVKEFVDKFKHSSAELSGPVALRRRNSKFDFNRS PHVDKKSR-EQFEQRTSGRLIVLHGLTPAMMQMLGDSSFPPGVEIYLKIKKVFCGVVTKAKCDKTVKVSVLRVYKDKLYK KVIKRYKEYTVHDEN--NSCKEGDKVFIQEHRPISATKKWVIVRVE---------------------------------- -MSRSA-WKPPFCHP-SVLRLVNRALK---QGSIN---KVIKIHSRASVILPNCLGLKFAVYNGKDYIPVSVNDQNMIGH KFGEFSPTRKFAGHN------G---DK----KAV------RR >ALPHA_Wolbachia_pipientis_wPip Concatenation of 2 sequences MGMKFFNPVTPSSRGTILISKIG-LSKD------------KP-EKSLVFGKKSSGGRNNHGRITTRH-RGGGHKKK---- YRVIDFK-R--NR-SDQ-GIVEKIEYDPNRSGFLALISYKEDDTKSYILAPQGMKPGDVVTAGD-D-AD-ILPGNCLLLK HIPVGSFVHNVELKPGNGAAIARAAGCYAQIVGR--DGQYVLLRLRSGQIRLILSSCKATIGVVSNLDHKNRKLGKAGRS -RWL-----GIR-P-AVRGVAMNPVDHPHGGGEGKT----SGGRHPVTP---WGVATKGKKTR-KKNKSSD-K-YIKKLK --------------------------------RRI---G-LLMTNVGHTAMY--FDNS---------RMAVTLLHLSETY IIDIK----GQD----K--CGY--NSVILGT-------GD---IAK----------PQLEYLK----------------- ---KG-INSKCKLYESRL--------TDLFGI-----EC---GK-KVGV--N-H-FVVGQYLDITGYSLGKGFAGVMKRH NFSG-LRASHGVSIAHRS-QGSTGQC-QDPG-RVFKGKKMAGHLGNSRVTVQNMKILSIDYENS---------------- ----------IIAVKGNNVPGFKNSYVFVR--MECELVD-LSNNNV-GSVELNPLIF----SA-KQ-KLSILHDIVRWQL AKRRVGAHKTKGISD--------VS-GTTAKPY---------GQKRTGRAR--------QGS---LR-SP----QF---- RGGGIIFGPV-V-RSHAYSLNKKVRKFGLKIALSLKYLNN----------------Q-VVVLDSL----NVD-V------ --KKTSLIV---GDYG--D---DLLRAAKNLHYVD-L---------------IKPIGLNVFDILNHEC----VMLTKDTL KHLE-MFKQLYKDNI----VKSLKDKFNYSNVMQVPKLVKVCINMGVG-DAATDNKAINEPFDNLHSIAGQKPVLTFAKK SISGFKIRKGATVGCKVTLRRNKMYEFLERLIYIALPREKDFRGFSV-KQFDGHGNFSFGIKEHISFLEID-----YDKI SKIRGMDINIITS-----------------------AVSDKEAKELLLALKFPFMSRIG-A--APINIPADLSVE-Y--- ---N-NG-RVLIRSVRAEKELNL--CS-G--ILCQIVD-NQ--LLLSVDQG-R--DDYDKIK-SIWGTYRSNINNMINGM VNDFSVDLEINGVGY--KAECDD-KY--LTLY--LGYSHNIKYKV-P-K-DVEIKCI--K-PTHLVIRG-MDKQKVYMVA SDICKIR------KYDPY---KGKGIVIKGKFMLRKVVN----------MIQKNTLLEVADNSGARAVLCIGLL---GRK S--ASVGDTIIISTKSINPK-G-------KVEKGKVYKAVVVRVKNSVKKSDGSVIRFSSNAVVLIN-DQGE-PLGTRVF GPVKKLL--SGSFMKIMSLADEVLVK-L--NSIFTKLSK-KKKPKLLG-RGIGCGK-GKTSGRGHKGQKARSGVS----- -INGF-E-GGQQSIYTRLPK-RG--FKPFNVGDVIDKELLHKL-GFIRIK---------LLN--KGK-L-R-E-K-FVF- HVDFASEAAKRSVASVGGSV-K---VFK--GRI---KGNA-KGGSTLSFG----------DYGLKAM--EVGKVQSKHIE TARRVISRTL------KRSGKVWIRIFPDTPVSKKPADVRMGKGK---------GSIEFWVFKAKP-GRVLFEI--SS-D VPMHLARLALEKATAKLPMKCKF-IFLSSYEKRKLRNRAKL---DKSAGRLRISIFKSNKHFYVQLIND---A--KGTTL ASASTL-DDKI-RNVC----KGR-VNAETIKQVSSLLIER--LPSTKLQQRFVFDRGAYKYT--GLISQFAEALRSSGFK F-------------------------------------------------------------DII-VEAGSKVLRSTPRK LNLVADLVRNKKVSFANVQLRFC---------------------------------EKKAAGFIMKVLNSAIAN----A- QNNY-GLNVDNLYIKEILIGKSLTLRRVYPKAMGRANRMSKFYSNITIKLKESAKIKSGDDIIVLTGK------DK-KKI GKVIKVIIRNAKKKVV--VSGVNVCKRHTK----PR--AG-S-G-GGIFNKELAIDVSNVA-ILDPKY-------KT--P --TKVGFKI----I--------DGKVR---FAKVSG---EVI--MGQKVNPKVFRLQ--INSNTWDSVWCA------T-D D--YKQKLHQDLFIRSYI--NESFK-----HAGISKVTVERTV-T-LVSVIIHSSKPGVIIGKKGLDVEKIKQKIAKKVE VNVVGVKK---SEIDAVLISRSITHQLEKRISCRRAMKKAIQNCLKM-GAEGIKVSCSGRLGGAEIARTEWYKEGRLPL- -HTLRANIDYAFCEAKTICGIIGVKVWVYMSLSDGIGDFLTRIRNAQLAMHRETRV-LFSKVNSSILKILKEEGYILNYE KQE----S---D----SIPSLVVQLKYY----DK-------S---PVINDIARVSKPGCRYYSKCKDISKAYNGLGIFII STPKGVMTDYNARRLKVGGEVLCRVF-MKQDIYIRIKAFDCSLLEKCIREFIDQLKQFNADLSGPIALPRKDSKFTVNRS PHVDKKSR-EQFEMRISKRLIIVHNPTSTMMKMLADLSFSAGVEVDLKVKKVFYGVVTKADSDKTVKVSVLQVYKDRLYK KVIKKYKKYTAHDEN--NSCKKGDRVLIQEHKPISVTKKWVVIN--S--------------------------------- -MSRSV-WKPPFLHP-SVLRLVQRALK---EGSIN---KVIKIHSRASVILPNCLGLKFAVYNGKDYIPVSVDNQNMIGH KFGEFSPTRKFTGHG------G---DK----KAT------RR >ALPHA_Xanthobacter_autotrophicus_Py2 Concatenation of 2 sequences MALKHFKPVTPSLRQLVIVDRSG-LYKG------------KP-VKTLTEGKSSSGGRNNNGRITVRF-RGGGHKQT---- YRLVDFK-R--TK-RGVPAVVDRIEYDPNRSAFIALIKYE-DGDLAYILAPQRLAVGDQVIAGE-Q-VD-VKPGNAGPLS SLPVGTIVHNVELKVGKGGQIARSAGTYAQIVGR--DQGYVIVRLNSGEQRLVLGACYATVGAVSNPDHMNISLGKAGRN -RWL-----GRK-P-HNRGVTMNPVDHPHGGGEGRT----SGGRNPVTP---WGFPTKGKKTR-NNKA-TD-K-FIVSSR --------------------------------MRS---G-VIAQKVGMTRIFT-DAGE---------HVPVTVLKVESCQ VVAHR----TLD----K--NGY--VAVQLGA-------GR--RVTR----------AERGHFV----------------- ---AQ-VEPKHKLAEFRV--------PEEALI-----PV---GA-EITA--D-H-FVVGQYVDVTGTTIGKGFAGGMKRH NFGG-LRATHGVSISHRS-IGSTGGR-QDPG-KTFKNKKMPGHMGDVTVTTQNLKVVMTDVERG---------------- ----------LIAVEGA-VPGHAGGWITVR--MEITVKT-LDGIEA-GSVTLSDEIF----GL-EP-RADILHRCVTWQL SRRQAGTHRTKGRSE--------IN-RTSKKMY---------KQKGTGNAR--------HGA---AS-AP----QF---- RGGGRAFGPV-V-RSHAIDLPKKVRALALKHALSSKAKAA----------------Q-IIVLDKV----SLD-D------ --PKTKLIV--DGAQE--Q---NVALAARNLPYVD-V---------------LPIQGINVYDILRRDT----LVLTKAAV DALEPKLRTFYDEVV----RPKMIEQFGYKNPMEVPTIDKIVINMGVG-EATADTKKVTTAAADLAQIAGQKPVITRARK AISNFKLRENQPVGAKVTLRKARMYEFMDRLVSIALPRVRDFRGLNP-KSFDGRGNYAMGVKEHIVFPEIN-----YDRV EQIWGMDIIVCTT-----------------------AKTDEEARALLKAFNFPFMSKIG-K--LPVAIPAGVTAS-L--- -D-G--Q-TVKVKGPKGALEVTL--VE-E--IAAKIEG-SE--LKV----S-M--NGETRHK-AMWGMSRTLVANLVEGV TKGFEKKLEITGVGY--KAAVQG-KN--LNLS--LGYSHDVIYAI-P-E-GIQIVTP--K-PTEVVISG-IDRQKVGQVA AEIREFR------GPEPY---KGKGVKYAGEFIFRKEGK----------MIQMQTNLDVADNSGARRVMCIKVLG-SKRK Y--AHVGDIIVVSVKEAIPR-G-------RVKKGDVMKAVVVRTAKDIRRVDGSVIRFDRNAAVLIN-NKRAQSWDQTIA LSIARR---NEGYTRIQAQPPHARMN-L--EDIRDNPGA-RKKRMRVG-RGIGSGK-GKTAGRGVKGQKARTGVA----- -IKGF-E-GGQMPLHRRLPK-RG--FHNVSLGKIVTEAALVAA-GVLRVR---------VLG--TGE-L-S-A-K-VTL- EVAYATKSAVAAVEKAGGSV-K---QFK--GRI---HGVA-KGGTELNFG----------EFGLKAV--EPERVTARQIE AARRALTRHM------KRAGRVWIRVFPDVPVSAKPTEVRMGKGK---------GAPEYWAARIKP-GRIMFEI--DG-- VSVETAREALTLAAAKLPIKTRF-IDLEALARRKAKVRRAI--RVAANGRPRLSVHRTSQHIYAQVIDD---A--NGETL AAASSL-EKDL-RTSL----KTG-ADTDAAKTIGKLVAER--ALAKG-VTAVVFDRGAYIFH--GRVKALAEGAREGGLQ F-------------------------------------------------------------DNE-AKAVLRNLRISPQK LNLVAGLIRGKKVATALADLEFS---------------------------------HKRIARDVRKCLESAIAN----A- ENNH-ELDVDDLVVAEAHVGKGLVMKRFSPRARGRASRIEKPFSHITIVVREAAKIKKGDKVVVLTGR------DK-GRT GEVIQVMPKEE--RAL--VRGVNIVKRHQR--------QTANQE-GGIISKEAPIQLSNVA-VADPKD-------GK--P --TRVGFQV---LE--------DGKVR---VAKRSG---ERI--MGQKVNPVGLRLG--IN-RTWDSRWFA----N-K-G E--YGKLLHEDIKIREML--FKQLK-----QAAVSKVVIERPH-K-KCRVTIYSGRPGVVIGKKGADIDKLRKKVSEMVF INIVEIRK---PEIDARLVAESIAQQLERRVAFRRAMKRAVQSAMRL-GAEGIRINCSGRLGGAEIARLEWYREGRVPL- -HTLRADVDYGTATAFTTYGTCGVKVWVFMAVTDPIGDLITRIRNAQMRRKDKTST-PGSRLRASVLEVLRSEGYIRGFT ATD----H---G---NGRTEFEIELKYF----DG-------V---PVIREIARVSKPGRRVYASVKNLPRVANGLGIAVV STPQGVMADHEARDKNVGGEVLCTVFMNGQNIRIRLKAFDHRILDASTREIVATAKRTGAQVRGPIPLPTRIEKFTVNRS PHIDKKSR-EQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLKRVLQGVVVSDKTDKTVVVRVERRFTHPLLK KTVRRSKKYHAHDEA--NAWKVGDTVWIEEHRPISKLKNWIVIQGEKRA------------------------------- -MTRSV-WKGPFVDG-YLLKKAEAASG---SGRRD----VIKIWSRRSTILPQFVGLTFGVYNGHKHVPVNVSE-EMIGH KFGEFAPTRTYYGHA------A---DK----KSK------RR >ALPHA_Zymomonas_mobilis_mobilis_ZM4 Concatenation of 2 sequences MALKHYNPTSPARRGLILVDRSS-LWKG------------SP-VKALTEGKNKTGGRNNKGHRTSRG-IGGGHKQK---- YRLVDFK-R--RK-WDMPATVQRIEYDPNRSAFIALVEYE-DKTLSYILAPQRLGVGDSIVASR-K-AD-VKPGNAMEIG QAPLGTIVHNIELKPSKGGQLARAAGAYAQIVGR--DKGMVMIRLNSGEQRYIRSDCMVTVGAVSNSDNANQNFAKAGRN -RWL-----GRR-P-LTRGVAKNPVDHPHGGGEGRT----SGGRHPVTP---WGKPTKGARTR-SNKA-TD-K-FIIRSR --------------------------------MRT---G-VIAKKVGMTRLFQ-EDGR---------HVPVTVLKLEDVQ VVAVK----NKD----Q--DGY--VAVQLGA-------GS--AVTK----------PVRGHFK----------------- ---AE-VELKAKLVEFPV--------SEDAVL-----EV---GT-SISA--D-H-FIAGQLVDISGQTQGKGFAGAMKRW GFGG-LRATHGVSLSHRS-HGSTGNR-QDPG-RVFKNKKMAGHMGARQRTQQNLEVISTDAERD---------------- ----------LIFVRGS-VPGSKGAWLIIR--MKVEVQS-LDASKK-GSIELNDAVF----GI-EP-RADILHRVVTWQL EKRRAPTRATRERSD--------VA-RSGKKFG---------RQKGGGTAR--------HGD---RR-SP----IF---- IGGGKAHGAR-A-RVFNPSLNKKVRALGLRMALSSKAKTG----------------T-LVVIEAL----DVE-------- --AKTKLVV--DGDTN--E---NFARASSNLVGLD-V---------------LPAVGANVYDILKHDT----LVLTRAAV EKLEPRLKKQYDDEI----IKAMTEKFGYKNAFEVPKLTKIVLNMGVG-EATQDKKKVDQAAAEMELIAGQKPVVTRAKK SIAQFKLREGMPIGVKVTLRRERMFEFLDRFLTIALPRVRDFRGLNP-KSFDGRGNYATGIKEQLIFPEIS-----YDQV STIRGMDVVVATT-----------------------AKTDEEARELLRLFGFPFMSRIG-K--KPVAIPTGVTAN-I--- -A-D--G-VLSVKGPKGELSMPL--SS-E--VTYSLED-GQ--LSV----Q-P-VNDTKRAR-SFWGMQRTLVQNLIDGV TQGYSKTLQITGVGY--RAASQG-KT--LKLQ--LGYSHDIDFAI-P-E-GITIQTP--E-PTTVNISG-IDKQKVGQVA AEIRRWR------RPEPY---KGKGIKYAGEFIFRKEGK------------------------------MHKVLG-SKRR T--ATVGDVIVVSVKEAAPR-G-------RVKKGDVHRAVIVRTAKDIHRADGSVIRFDGNAAVLINKTSGE-PIGTRIF GPVVRELR-ARNHMKIISLAPEVLFK-L--NSLKDNAGS-RVGRVRVG-RGIGSGL-GKTAGRGQKGQKSRSGVS----- -INGF-A-GGQMPIYMRLPK-RG--FNNVNLGVVIDHQALKAA-GVARVR---------ILG--KGE-I-A-S-K-VAF- KVAGISKAAREAVEKAGGSV-K---AHK--GRI---HGNA-PGGATLNFG----------AYGLKAM--EPDRITARQIE AARRAITRHI------RRQGRLWIRIFPDVPVSSKPAEVRMGSGK---------GSPEFWVARVKP-GRILFEL--DG-- VPGPIARVAFERAAAKLPIKVKV-VRRRQRVRTTLRAKGNH--------RPRLSVHRSGQHIYAQVIDD---D--QRRTV VAASTL-EKAV-RD------KSG-ATVAAAAETGKRLAER--ASAAG-ITKVVFDRGGFLFH--GRVKALADAAREGGLE F-------------------------------------------------------------EKE-ALAVATTVRGSSYK LNLVAGLIRGKKAGEALNILSFS---------------------------------KKAMAKDVRKVLASAIAN----A- ENNH-NLDVDALIVKEASVGKSIVMKRFATRARGRSTQIIKPFSRIRVVVREAAKIKKGDRVVILSGK------DK-GKH GEVTQALPQEG--KVI--VSGINIITRHRK----PS--QA-NPQ-GGLDRMEAPIAASKVA-IEDPKT-------GK--A --TRVRFDV----R--------DGKVR---IAVKSG---ETI--MGHKSNPIGMRLQ--IN-RTWDSRWFA------QGG D--YGQLLLEDIKIRKFI--MKTLP-----QAAISKVVIERPA-K-LCRISIYAARPGVIIGKKGADIEKLRKKLDSMVS LNIVEIRK---PEIDAQLVAQGIADQLERRVAFRRAMKRAVQSALRL-GAQGVRITCGGRLGGAEIARTEWYREGRVPL- -HTLRANVDYAEAEAHTAYGVCGIKVWIFMALSDPLGDLLTRIRNGQHARKDSVVS-PASKLRVRVLDVLAREGYIRGYT EAK----L---G----NHDALRIELKYF----EG-------Q---PAIHHLARVSKPGRRIYSGSRELPRVRNGLGITIV STPKGVLSDAEARDQNVGGEVLAEVF------------------------------------------------------ -------------------------------------------------KRVLTGTVVSDKTDKTVVVLVERKVKHPLYG KIIRLSKKYHAHDEQ--NAYHEGETVRIEECAPISKLKSWRVLEKADKA------------------------------- -------------------------------------------------------------------------------- ------------------------------------------ >ARCH_Aeropyrum_pernix_K1 Concatenation of 2 sequences M----------GKR----------LRQQ----------------------------R--AGRGTPTY-RSRAHIHPGPAK YPPLS---G-----DTLRGKVVELIHDPGRYVPLARVVRE-DGVEFLMPAAEGMYVGQIIEIGP-A-AK-PEAGNILPLG KIPEGTEVFNVELRPGDGGKLARQAGSYALVVGR--AGAKTILRLPSGKDKEVPNDSRATIGIPAGAGRIEKPIMKAGFA -YHKWKVKARKW-P-RVRGVAMNAVDHPFGGGRHQH----KGRPSTVAR----TAPPGRKVGH-IAARRTG-------RR ARKKRAPRRGSLGFSPRKRASRLVPRVKRWPEVPL---A-FLGYRAGMTHVFMVDDRPGRPTSGKEIFVPVTIVETPPMF VAAVR-----------L--YGYDPNRGRYSL-------GEAWALQR--------RISTLGSFEERLDKAEDVRLIAASQP KLAGGLSKKKPDLLEIKV--GGVSDVTKLFDY-----AKDVLGN-LIAV--NDV-FEEGQLVDVIAVTKGKGFQGVIKRW GVKE-LPRWHKHRKGSRR-IGA-----RSHGRSTFWETPQAGQTGFHRRTEYNKRILMIDDDGY---------KVTPAGG FLRYGVVRSTFVMLSGS-IPGTPKRPIVMRQEKIVPVYD-ERGGEK-DSVVLPQ-IF-----RFPV-RKDLIRRAFLSEF TARLQPKGRDPMAGKRTSAVSLGVGRGVARVP----------RIKGSLRAA--------------LVNMA---------- RGGRAAHPPR-VEKVLKEYINKKEKRLATISAISATSREDLVRQRGHRFSA-----ETLPIVLDSSVLAKI--------- --STARLFV--LEDPR--S---PLALAVKGMPGVD-V---------------VTPTLLSVLHLAPGGHPGRLTIYTTEAL KLLSVSAKAQSPERV-----SEILDEWK-RSPMRRPRIVKVTVNISIG----QSGERLQRAAEVLEELTGQKPVFRKAKR TIRAFGVRKGENIAVMVTLRGEKALNFLKRALDAVGHRIKT-------SSIDEHGNVSFGIEEHILIPGVK-----YDPR VGILGMDVAITIQ-RPGHRIVERRRQRRGHIPRRHRVTREETMVLLNQLFGVTFMAKDV-HVVERVEVPEGVTVS-I--- -D-G--M-RVKVSGPKGEVERDF-SHARG--VLIRLED-NS--VVV----E-S-FFAKARQR-ALVGAIAGHIRNMIKGV QGGFRYKLKIMYSHFPINVKVEG-DK--FIISNFLGEKGLRIARIMP---GVKVQVK--G-S-DVIVEG-IDVEKVAQTA ANIELAT------KVKDK---DRRK-FMDGIYIYEREVIVVVSRYGVNTGLQVGSYVPVADNSGAKEVMIISVPT-RLRR LPSAGVGDLVVVSVKKGTPQ-----------MRRQVVYAVVVRQRRPFRRPDGTWVSFEDNAVVIVN-PDGT-PRGSEVR GPIAREA--AERWPRVAKIATMIV------MVVRRRK---KSRKLRGRTRTMSWGRIGQHRKSGSKGGYGAAGLGKHE-- -WTWT-I-K-YAPTWY--GK-KG--FNPINVGQLEDGKIVVNL-EKL-HK---------LLG--EGR-V-A-R-P-LKV- ITPLASELAIKKIEEAGGEVMH--FSGPPYTRREYIHGVPPPKITRFEMG--NREMMEKWEIKGELVMLEAGQIRHNALE AARIAVNKYLATTIG-DKNFYFRIRVYPHHVIRENKMMAFAGADRLQDGMRQAFGKPVGTAARVYP-GTVVLEVWARK-- GDEENVKEALRRGASKFPLPSRI-VRVPLRRRREGKTNYYRRFRLVKSGKPRMAVRISNEYLWVQFLEA---RIEGDRVI AAAHSR-ELIKKFGWK----GDG-NNTCAAYLTGYLAGLR--ALEKG-VREAVLDVGLHKPVKGSRVFAALKGALDAGVE IPHSEEILPGDERVRCEHIAQWAEALKEENAELYQRQFSRYLDRGLNPEELPGHVEEVKKAISEV-AKAVLRNVPVHPKI MAEVARAISGMRVDEARRYLRAVIEKREAVPFRRAHGKQAHRRGLADKWGWPVGRYPVKAARYMLKLLDNVEAN----A- ANK--NLDVERLKIIHVAAHKGITLKRWMPRAWGRATPRNRVHSHIEIMVRESLPVRKGDKVRVMRGD------FK-GHE GKVVKVDLRRL--RIY--IDGVTVTKADGT----PV---------------FRPIHPSNVM-IVELDL-----------S --DEYRKKM---IE----------RRA---AGRRGG---GNS--VPTKVVKHFLNQG--LL-R--------------T-- ------------KIDEWL--AQNFY-----EAGYSRVKVVQTS-L-GTNITIWAERPALIIGRRGATIRRLQEVFQTVPR IRVEQPEN---PMLDARVQAFRIARSIERGIHFRRVAFAAINRIMSN-GALGVEITISGKLTS-ERARFEKFKAGKVYKS GHKVDELVDRASAYARLPKGVIGVDVIIVMVMLDTLANAMAAIKNAEMRGKGEAIIMPSSKLIANVLRILEKEGYIGGFE YID----D---G----RWGKFRVKLLGR---IND-------I---GVVKPRTPVSYRELAKMPEHLRKYLASRDVGLLIL STPQGVMTHREALKRKIGGIVIAYVY-MAFKLRIWLWSTNVRSLENVVEQIRNIANKTGIRMRGPVPLPVKRLEVPVFRL PHGEGSKYWEHWEMKVHKRLIDL-EADERVLRHLMRIKVPEDVYIEIKQGVLLEGVVAKARARRMVVVQHVYLYYDKKYN RYERRSKKIHAHLPDC-ISVKEGDVVVIGETMPISKTVKFTVLG--VKRRPEWKKFRYRGRTLEELLKMDIEELARLFPA RQRRSL-LRGLTPAQQKLLLKVRKIRR---RLEEGKRPPVIRTHVRDMVILPEMVGLTIAVYNGKEFIPVKIVP-EMIGH YLGEFSPTTRIVQHG----EPGLKATR----SSL-HVASK-- >ARCH_Archaeoglobus_fulgidus_DSM_4304 Concatenation of 2 sequences M----------GKR----------IISQ------------------------------NRGKGTPTY-RAPSHRYK--TD AKLLRFK-D-----EVVAAKVIDIQHDSARNGPVALVKLP-DGSETYILAVEGLGTGDVVYAGD-N-VE-IASGNITYLK NIPEGTPVCNIEAQPGDGGKFIRASGTFGFVVSR--EADKVLVQMPSGKQKWFHPNCRAMIGVVAGGGRTDKPFVKAGKK -YHKMKSKAAKW-P-RVRGVAMNAVDHPFGGGKHQH----VGKPKTVSR----NAPPGRKVGS-IAARRTG-----VRR- -MKYHRPRRGSLAFSPRKRAKSIVPRIRAWPEDRVRMQG-FAGYKAGMTHVVMIDDRKNSPTYGEEVVVPVTVIETPPMK VAAVR----VYK----K--TQYGMQIAAEVW------SNN--LLDR--RLNLPKKEPDVEKLAAVENGASEVRVVTYTQP YLITGVPKKVPDVMEHRI----GGNVEEALDY-----AISKLGK-EISV-SE-V-FDEGAIIDVIAVTKGKGFQGPVKRW GVIT-LDAKHARSSKHRR-VGNLGP--WNPH-HVRWTVPQAGQMGFHQRTEYNKRLIKIGENGE---------EITPKGG FLHYGVIRTQYVLVTGS-VPGPVKRLIRMR--MKAKVLN-LKGEVT-EEIELPEVFA----E--EF-RPDIIKRAVLALQ SHRRQPYGPNPLSGV-----------DYSWENW----------GPGHGYARVPRWKLG-RRA---VV-VP----QA---- VGGRRAHPPK-PERKWAEKINKKEMRKALKSAIAATANEELVRQRSHVFEGEL---P-KVVSNEL---ESV--------- --KRTKLLV--VGKDD------GVVKAAKNLPGVD-A---------------VVVKDLNVELLAPGCHPGRLTVWTKSAV EYLG-------MQAV------EMEKKAGNENPMREVVLDKVVINIGVG----ESGERHKKAYSLLEELVEQKPAITYAKM TIKNFGIRKGEAIGIKVTLRGEKALKFLKDALTVKENRLS--------RKSIGEGYFAFGIAEHIDLPGVD-----YDPD VGIFGMDVCVSLK-RRGYRVARRRRKKAKIATSH--RVTKEDTIRWLESLGVIVTEVYE-E--RVVEVPEDVQLTIEGDS FR-G--Y-TLKAVGPKGENTRYL-KYR-G--VFIEVGD-GK--VRV----Y-T-TSPKKKHK-AMVGTFAGHIENLITGV KEGFEYHLKVVYAHFPIKVRVEG-NE--VIIENFIGEKHPRRAKI-V-G-RAQVEIS--G-Q-DIYVRG-IDIEECGQTA ANLEQAT------KIKRK---DPR-VFQDGIYIVKKP--MKAIRANIPRALPTGARLVCADNTGARELEIIAVKG-VRRR YPAAGVGDIVVVTVKKGTPE-----------IRKQVHYAVIVRQRKEYRRPDGTRVKFEDNAAVITN-ERGE-PRGSEIR GAVAREA--AERFSKIGTIASVIV------VILMPKK---KVKKFRGS-RTFGWGSHKNRRGRGNRGGAGNAGVHKHK-- -YIKF-V-K-LAKKLF--GK-HG--FTRLNAGDLEGDVYRIDL-AEL-SK---------LLG--SGK-V-T-R-K-MEV- KVFEATPKAVEKIEAAGGKVMR---LERPYTRTEYIDGAPGTRVRMFDMG----NKSADFPVMLTLVAKEAVQIRENALE AARVVANKYVSRRAG-ASNYKLKLRIFPHHILREHKMAVGAGADRISQGMRAAFGKPVGRAARVKP-GTKIMSVWVKP-- EHFEIAKEALRRAAMKMPTPTKI-VKVPLRRRREGKTNYRKRLKLLLSRKPRLVVRITNRRVIAQIVEY---APEGDRVV VGVDSA-MLRE-FGWK----GDL-NNTPAAYLTGILIAKK--ALQKG-IGEAVLDIGLHTPTRGSRVFAVLRGAVEGGLE VPHSDEVLPDDSRIRGEHIAAYYEMNPE--------RFGEYEKRGLKPSDLPAHVDEIKEKLTKA-AKAMGYEMPISFKH AVEICRAIRGKKIEEARKLLEDVVEMKRAIPFKRHKKKVAHRRGLE---KWYAGRYPQKAAKYVLKVLRNLEAN----A- EYK--GLDVENLVIVHAQAQKGRVIERYMPRAFGRATPRFQQLTTVELVAEVAIRVRKGDKVRIMRGQ------FA-GHE GRVLEVDMKRC--RIT--VDGVTVTKADGT-------------------EVAVPIHPSNVM-ITDFGE-----------V --DEVRKKI---------------LER-----------------MA-------------VE-R--------------K-- ---FVQERLKKLMVKEWI--KDEVR-----SAGFGGVDILRTP-L-GTQVTLFVERPGLVIGKGGRRIKALTEKL-KDPQ VSVDEVEK---PEFNAQLMASLLARALERGWYFRRAGYRFLYRIMEA-GAKGCEIEISGKLVS-ERARTEKFVAGTIVHT GDPAESMVQKGFDIAIKKLGVLGVSVRIIVMSVDTLSNAMIAIKNAEMVGEKKCEIKPASKLIGNVLKVMKDYGYIKGFE YVE----N---H----RGGKFIVELSGN---IND-------C---GAIRPRFSSSVTEYEMYEKR---YLPARDFGILIV STTKGVMSQKDARKQRLGGVLLAYVYIKGPKARIKLSGLNPRELDRICSQIKEIANKTGVELSGPVPLPTRRMVVPVRKA PDGEGSETWDHWEMRVHKRLIDI-SADERALRQIMRIQVPRDVNIEIVLGQLLRGKVVKV-YGKTAVIERELIRYVPKFE RYMKKRSKLHAHNPRC-IRARPGDIVTIGECRPISKTKSFVILEVVGNEVIRPRDFKYRGYTLEELQKMPLEELAKLLPA RERRKI-KRGFTEQEEKLLRKLRKKGT-------------ARTHCRDMVVLPEMVGKVVFVHNGKEFVRVEIKP-EMIGH RLGEFALTRRFEKHS----GPGVGATR----SSK-YVPLK-- >ARCH_Caldivirga_maquilingensis_IC-167 Concatenation of 2 sequences MGKKI-------------------LVQR-------------------------------AGRGGSQF-RSPSWRRI--AP LRYVQFSEQ--LK-TTIRGIIKELVHVTGLNAPAMHVVLE-NGEEMYLPAVEGVYVGKIIEFGP-D-AK-VEPGNVMPIG KIPEGTMVCNIEKRVGDGGKYARSSGTYGVVMIH--RDSTTLVQLPSGRMIEVDSRARATIGIVAGGGRIEKPFVKAGNK -YHRARTKAWKY-P-KVRGKAMSAYAHPHGGGSHQQ----GGT--PVKK----NAPPGQKVGF-YGSKCTG-R-GCVRWR GLKIHRPRRGSMAYYPRKRASDIVPRIRNWPVTLL---G-FVGYKAGMVHVTVVDDRKTSPFFGKELVKAVTVVETPPLY VVGLR----AYA----I--NPL--KAELVSV-------GEAWVTDK-------ALADLQGLL------SVSYIKVIAMTQ PYKAGVGKKTPEVLEIPV--GGVPTIDEQFKY-----ASGLLGK-EVKP-TD-V-FKPGQLVDVIGVTKGKGTQGVIKRF GVKE-LPRWHKHRKGSRR-TGTVG---PKPA--VMYTQPRMGQMGFHRRTEYNKRILKISDNGS---------EITPKGG FKHYGIVRSGYMLIEGS-TPGVVKRLIAFRVPAKAKLLN-LNGEAV-GEVDLPEHFK-------TPIRLDLIRRAVLSAL TARLQPKGTDKEAGLRTSAVSFGTGLGIARVP----------RIKGNMWPR--------------ARIAP----NV---- VKGRRAHPPK-VEKRLWERINRKERLLAIRSAIAATAVRELIMARGHLVGDVKAI-P-LVVVNEF---EGI--------- --SKAALVV--VSRKD--A---PVIRAVRNMAGVD-V---------------VYVDNLSILHLAPGGVPGRLTLWTQGAI ERLSIDLSTIDLRAIKPSDLDWRKFTLDTGHPMRRIFIWSVAVNMGIG----QSGERLEKAAKVMSELTGRTPSYRLAHK SIKDFGIRRGEPIGLLVTLRRNEAVWFLLRALAAVDFTLRE-------ESFNA-GNVSFGIREHILVPGSR-----YDPA LGIFGFDVAVTLA-RPGFRVQYRRRARADVGKDHR-VSREETIRFFQDVLGVRIMAKVP-YLSDTIEVPDGVEVN-V--- -E-G-GE-LVTVKGPLGSVAKEF--KGLP--VLVSLRD-GK--VVV----E-G--FALRKAK-STVFTVAGHIRNMIIGV TKGWRYKLKVVYAHFPISVKVQG-NS--VVIENFLGRRSKIILQI-P-Q-GVKVQVA--K-D-DIVVEG-IDKELVSQFA ANIELATTLRGKNRPSPHGRESAPGI-LDGIYVYASENIGVPWRFHLTPGIFMNSLVNVADNSGAKVVKVIGVVN-VHRR IPGVSVGDMVVVSVQEGKPE-----------MRKQILRAIVVRQRRPFRRPDGTWVAFEDNAVVIVT-EEGQ-VKGTEVH GPVAMEA--AQRWPQVASIATMIIMR-R--RE--------KKSRKLRGWRTHSWGRVGQHRSRGQRGGGGKIGLLKHKKS LLLKI-TNGELYPL---IGK-HG--FYRINVGDLRNLIKMEGDKYIIDGK---------LLG--EGK-I-Q-K-P-VVV- KVRAASAKAIKAIKEAGGEVMR---IKRPYTRLKYIHGAPYVQIPRFEMGATKAKDRERFTSVAVLRVLEGGQIRVNALE AARQMAYKYLSKVLT-DQNFYLKIIKYPHHVIRENKMLAMAGADRLQEGMRLAFGVPTGRAIQIEP-GEVLMIVEVED-- RNITHAKEALNRARAKLPLPCRIELKVKFRRRREGKTDYYKRRIMVISGKPRLVVRFSNRYVLAQVIVS---APQGDFTV AEASSR-ELVKKFGWL----GGT-GNTPAAYLVGLLIGYR--ALSKG-IKLAVLDVGLHRVTKGGRLFAVVKGAVDAGLE VPHDEEVQPSEDRLNGEHIAQYAADLKQSNPELYKIRFSKYLARGLEPENISKHIEEVKSKIDQI-AKARGFEFRISWKK AIETARAIRFLTIKQAEDYMEKVKDLKAPIPIKEFTRKQAHHNVPWD--GWPVAKWPVKVADSFLQVLRNLESN----A- SYR--GLNIDNTVIVHASASRGMRIRNYMPRALGRATPWFQDTVNIELVAVERIPVRVGDTVLILRGD------FK-GTR GKVTRVDYKRV--RIY--VDSASFKKPSGE-------------------AVYYPIHPSKVV-IVELDQ-------SD--K --ARVAAID---------------KTR---KAREAKAGVREVT-AQQRRLPMYKRI---ID--DNKKKWMI--------- --------------KEYL--NIALT-----RNRYVDSIIQRTT-L-GTRIVIIAEKKNRIIGRKGQQVKALADILKSKVV IDVIQEPH---PEYNARLVALRIADAMAKGIRFRRAAIIALRQLQEA-NVQGAEVIISGKLT-TERSRFEKYTTGIVIKA GQDALEKVQEAVIPVLLKPGIFSVRVRVLMVMLDVLSNALMSVKNAESRGDRQVIIWPSSKLIGNVLRVMQRYGYVGEFE YVY----D---G----RGGKYVVQLLGR---IND-------I---GAIKPRFHVKVDELQ---KWEEKYLPARQVGILIL TTSKGVVSHLEARENRVGGILVAYVYPVPRIVRIRIWGTNTDSVDGLARDITGIAKKLGIKVRGPIPLPTRRLMVTVRRA PSGQGYHTYDHWEMRIHKRVVDM-DADERALRQLMRLRIPEDVKVEIELGTILEGRVVSVYMGQ-VVIQHEWLHYSPKYK RYIRKRRNIHAHLPSC-IKVNVGDYVVIGETRPLAKFISFVVLGKRPDDQEEWKNFKYRGFTFDELMKMPMNEFIKLLPA RQRRTL-KRGLRPCHRQLLEKIRKAKAFAAKGKSI----PVRTHCRDMIILPEMVGLTIFVYNGITYIPVPISP-WHIGH YLGEFAITTKIVQHG----EPGLKATK----STL-HIAAK-- >ARCH_Candidatus_Korarchaeum_cryptofilum_OPF8 Concatenation of 2 sequences MGKRI-------------------LVQR-------------------------------RGRGGIQF-RSKDHLKI---- -APARYP-Q-----DGMDGVIKEILHEPGRHTPISLVELE-NGQEFYYIPPEGVYEGQEIQIGK-G-AE-VKTGNVLPLS EIPDGSLVCNVEIRPGDGGKIARRSGTYAIVFSH--EGDKVILRLPSRKEKLVDARCRATIGVVAGSGRIEKPFMKAGIK -YYHERTHPKRW-P-VVRGVAMNPVSHPHGGGSHKR----PGKPTTVAR----TAPPGQKVGH-IAARKTG-R---AKRR ----MPRRHGSLQYYPRKRAATQKALFRSYPEDKPTLVA-FPGYKVGMVHVLLKEDRPGKLNLGQQITLASTVIETPPIE IVGFR----AYK-------EGYGLKPLTTAL------RIE---ISR-----TLTIGEGVDNFSKLEGAKVSEIRILSYTR PDLAGIHKKKPEFMEIPV---KGGEMEERIEF-----AKSLVGS-QLKV--DSV-FKVGQLVDVTAVTKGHGWQGVVRRF GIEL-LRHKAGKGRWR---VGSLGS--RHPP-YVTWRVPRAGQTGYHKRTEYNKRILMMGDLTK------GDLDLSPKGG FKNYGILRSQYILLSGS-VPGPAKRFVFIRNPMEVPVYN-LNGEVI-GRIELPP-LF----EL-DV-RQDIIRRVYLSQL TARIQPQGRDPLAGLRTSAESLGVGHGIARVP----------RVKGRGYPA--------AGRA--AR-AV----MA---- VGGAKTKAPR-SWKVVWERVNKKERRLAIGSAIAATSHPELVGARHRIPEGIAL--P-IVVSDDI---ESI--------- --AKTSLII--YSRED--S---PLKLASRNIPGVD-A---------------VSLRNLSVMHLAPGGKPGRLTIWSESSI RALE-------MEDL----REEILRRWE-SNPMLIPRVMAVTLNIAVG----RSGEVLTRAGKVLEELTGQKPVERRAKR TIREFGIRKKEPIAVSVTVRGKKAVELLDRVAEAVGRRVKA-------SSFDELGNFAFGIKEHIDIPGVK-----YKAE IGIFGMDVIVSIG-RAGYRIARRRIERRRIPLRHR-VSRAESMLFAEKYLNLKVITLAL-E--SEVPIPEGVKVE-V--- -D-G--S-KIRVSGPKGTLEREF-HSE-L--IELSIEG-GK--VKV----R-T-YGKRKFNR-AYLGTVTAHIRNMMKGV TEGFRKEMVVVYAHFPIKVEVDK-GRKIVKISNFLGEKLPRYASI-V-G-DTEVRVE--G-D-RIYIEG-ISKEDVGQTA ANIRLAT------KIKKK---DPR-VFMDGIYVVR----VEGVKPKITHGLPVRARLKCADNTGAKLLMIIGVHG-RKDR VPTASVGDMVTVVVKRGKYD-----------LMHKPFKAIVVRQRMPYRRKNGQWVVFEDNAAVLVN-DDGT-PRGSEFR GPIAKEA--IERWPSLSVISAQVVMS-I--PRRR------KKSRKMRGSRLHGYGLQRQHRRSGRIGGFGMAGTKKHL-- -WTWV-T--AYEPDYFGRGR-RG--FKRINLADLSGVAEERED-GRIENK---------LLG--RGE-V-S-R-P-LLI- KVESASKNAVSKLESMGGGV----------MRM----------VAEASFQ-----------------------VRSNALE AARMTVLSQVRKAIPSDEAYFFKVVHYPHHILRKHAMAGVHKAERLQKGMRLAFGKPDARAAQIRR-GDVIMFMRVNE-- QHLEAAKYCMKLAKLKIPYMTRIDVKVKFRRRREGKTDYMKRLALLKSRKPRVVVRRTNRYIIVQFIGF---KGEGDEVI AYAFSK-ELEK-YGWP----YGG-KNLPAAYLTGYLAAMR--AKKAG-VTEAILDIGRFPSTKGSRLYAALKGVLDAGID VPHSPEILPDEDRIRGEHIASFAEKLE--EEGSLERQFSDYLRRGADPKIISEAFESVLERIEKE-AMASGRDLRVSFKE MVELLREIRGKKLSEAYNILDEVIALRRAIPFKRYNGGVPHRKGIS-----GAGRYPVKAAKLLKKILKSAEHN------ AMNK-DLDPDNLYVKHAAAQMGMKLRRFFPRAYGRASPKIEQMVHVEIVLEESIPIRKGDRVKVMRGD------YR-GTE GEVISVDRKRY--RIA--VKGIVRRKADGT-------------------EVPVPIHPSKVV-I----------------- --TKLYLKD-------------EARKR---LLERKGVKVEEIM-SSAKSMP--------IY-K--------------K-- ---FVQEGIVKYKLHEFM--EKISD-----KAGFHGVEISSTPIR-DI-ITVYVESPGVMIGRGGRTSKRISDILKEEPY IQAKKVDK---PFLSTRIVASYIARRIAKGERYKKVAYSALGRVMAE-GAKGVEIRLSGKF-GSQRAREERFREGVIYRC GQDYIENVEYAVKHVLMPQGMIGVRVRIVMTRLDPLADAMSTLTNGSMLGKREVVINIASKLIGKVLKVLKEHGYIDEFE YVD----D---G----RFGKYVVRLNGR---INK-------A---GVIKPRFPVK---VGEFSRWEKIYLPAENVGLIIV STNQGVMTHREAKERGIGGVLIAYCY-MTEILRIELVSVNPESLEKVSRMFKEIADKMGVRVKGPIPLPTKRLRVTALRN PSGEGTNRYDKYELRIHKRIIDIPNPDERYIRSIMGITLPDDVKISIVLRSSLDGRVISTKMTGTITVLVEYLHYDKKYK RYERRRSKIHAHLPPC-IEVSEGDLVRIVETRRLAKTVSHVVLG---KL-MSSREFRYRGYTLEQLQTMTLDELANVMPS RIRRTL-KRGLSIENKKLLDKIRKYKA---MGIDK----VIRTHRRDMPILPEMVGSKIAVHNGKEFVEITIVP-EMIGH YLGEFAMTNRIVRHG----KPGKGATR----SSK-FVPLK-- >ARCH_Candidatus_Methanoregula_boonei_6A8 Concatenation of 2 sequences M----------GHR----------ITTQ------------------------------NRGRGGPTY-RAPSHRYK---- AALKHIG----DGTKSISGSIIDIEHDPARNAPIALVQLE-DGSKVYILVTEGIGIGETVAWGA-D-VK-VKNGNTLPLQ SIPTGSYICNIESRPNDGGKFVRSTGVQAVVVDK--IGDRIGVRMPSGKTKWFNARCRATVGIVAGGGRVEKPFVKAGNK -SHKMRNTASNW-P-RVRGVAMNVIDHPFGGGGHQH----PGRPKTIAR----GTSPGRTVGH-VAARQTG------RSR MPKINRPRRGSLAFSPRKRAQSPIPKYKSWPEGAPALLG-FAGYKVGMTHVLMVDDHKDSPTEGKEIMVPVTIIEIPTMK VAALR----VYT----K--DTYGKHALTEIW-------AE---AKKKY-----SDALAAGLVE--------IYALAYTQP ATMSGVPKKVPDLMEIKV---AGGDIAKQYEY-----AFGLLGK-EIRL-SN-V-IETGAYADITAITIGKGTQGPVKRW GVTL-RKRKHSVGGKERH-VGTLGP--WNPH-HVRWEVPQSGQMGYQQRTEFNKRILKIGENGA---------EITPAGG FLNYGVIRNAYVVIKGS-IPGPAKRLIRIR--MKAQVKT-IEGGVA-KDIELPAMFS----E--EY-RPDLIRKAVLALQ STRRQPHGSYPYAGI-----------CSSAVGW----------GSGRGASHVPRLK---NGSRA-AK-VP----QA---- KGGREAHPPV-TAKVLIKEINAKEKQKAFRSAVAASIRADLISSRGHRFEGTV---P-LIFEDKF---ENL--------- --AKTQLIV---TSG-------PEFRAARNLAGVD-V---------------VTVDQLNVEHLAPGMQAGRLTVWTESAV IRLE-------MRDV---------------------HIDKVVVHMGVG----ESGEKLVKAENIMKTITKQTPIRSVAKM TQPAFNIRKGAPIGCKVTLRGKPAEDFIKTSLNIVNKTIFE-------SQFDKSGNFSFGIEEHTDFPGMS-----YDPQ IGIFGMDINVVLE-RNGIRITRRRMQKKKLPEKQR-VKKEDAIAFLKKEYSVEV--MAS-V--RKVRIPDGVKVK-L--- -E-Q--S-QLTITGPKGALVRSV-RFP-Q--VSVTCDG-KE--ITI----A-T-ESGRKEIT-AMVGTFEAHAKNMCRGV TDGFEYRMKVVYSHFPIQLKLQG-QR--LEIANFLGEKKARYADI-A-E-GVIAKVA--N-D-EVVLTG-IDREKVGNTA ANIEHAT------HIRNR---DPR-VFQDGIYMVQRG--MKAKQSKTPRALATGTKLTCADNTGARIVQIVSVFG-VRRR QPKMGLGDIATVTVKKGTPD-----------MRKKLVRAVVIRQKKEMRRPNGLRVSFDDNAVVVVD-EKNE-PKGTEIK GPVAREV--AERYPKLGSMATIIVMP-T--N---------KRSKYRGS-RTCGGGTHKNRRGAGNRGGRGRAGINAHHF- -VKWY-V-EMGGPVFGKDGF-----FHNMDVGIILAQGIAKQE-GDAVEK---------VLG--SGRVI---R-K-LNI- SAAAFSAQAKAKIEKTGGKAMN--LAKKAYTRREYMGGVPGNKIVQFEMG----NLSQEFPTEIDLIVEETCQIRHSALE AARISVNRKLLKDVG-RTNFHFKVRVFPHHVLRENKQATGAGADRVSEGMRLAFGKAVGTAARVEA-GQLLFTVFTTA-- QYLDKVKAALRNGSHKLPTPSHL-KLVAFRRRREGRTDYYQRTKLVVADAPRMVVRRTNRHIIVQLVTA---EMEGDKTL VSANSA-ELEK-YGYT----GAT-ANTPAAYLTGLLFAAK--AKKAG-QDSAILDIGLNRATPGARVFAALKGAVDGGLE IPYGESILPSEDRLKGEHIAAYN-E---------------------KAGDIVKNVEQVAAAIDNL-ARGKANELSISPKH SIEIADFIRHQRVNDALAYLADVVALKKAIPFRHFNRNVAHKRGLPG--NWDAGRYPVKASKAYIRILESIKKN----A- EYT--GLDTENLEIIHASANRGRAQKAYFPRAMGRASPKVRETVNIEIVVRETIRVIKGDTVKVTRGD------HV-GEE GIVDGIDTRNV--KII--VHGVSSTKVDGT-------------------EVPRPIDASKVE-ITKLKL------------ ----------------------DDKRR---VEKLGG---KE---MA-------------VE-R--------------K-- ---FIAEGARKARVEKYL--TKELK-----RAGFGGMDIARTP-L-GTQVTIFAEKPGIVIGKGGKLVHQLTQDLAQNPQ IEVQQVQN---PSFNAQIMAERLANALERGWYFRKAGSSIMRRVMDS-GALGCEVVIAGKLTGA-RARTQKFTEGYIKHC GEPSNTIVEKGYAIAIKKLGVIGVQVKIVMTRLNTIADGMSALKNAGDTGKSEVTIEPASKLLGAMLRIMQDAGYIAGFE FIE----D---G----RGGQLKVHLTGK---INK-------C---GAICPRFSVQ---LDEMEYWEKQYLPGKNFGLMIL STSHGVMSHVQARREGIGGELLGYVY--MQKARIRLTGTDFNKVETVCDRIREIAERTGVNLAGPIPLPTKRLVVPIRKS PDGEGTATFDRWQMRVHKRLIDI-DADERALRQLMRIQVPKDIGIEIVLGQVITGKVVSDKMMGTVVVARDYLHYVRKYN RYEKRISKLHAHNPPC-IQAKVGDLVKIAECRPLSKSTTYVVVE--VQQPRRREEFTYRGYKIDELKAMGLSELIPLMPA RARRKF-NRGLNRGEETLLEKIRGGDE------------KIRTHLREMIVMPEMIGKSIEIYNGKEFLKVEFQP-ESVFH YLGEFALTRKRVTHG----SAGIGATR----GSK-YVPLK-- >ARCH_Candidatus_Methanosphaerula_palustris_E1-9c Concatenation of 2 sequences M----------GHR----------IKTQ------------------------------NRGRGGPTY-RAPSHQYK---- AELKHLG-N--DK-VTVRGVIIDIEHDPARHTPIALVRLEGEGKKVYLLVTEGLGVGDQVAWGP-E-AE-VKNGNTLPIS KIPTGSYICNIEARPGDGGKFVRASGVQAIIIDK--TVDRVGVKMPSGKMKWFSSRCLATVGVVAGGGRGEKPFVKAGKK -FHKVKSQATYW-P-RVRGVAMNVIDHPFGGGGHQH----TGRPKTVSR----GTSPGRKVGS-VAARRTG-------RR MANIHRPRRGSLAYSPRKRAKSQVPKYHSWPAGEPILQS-FAGYKVGMTHVIMVDDHKNSPTEGKDIMVPVTIIEIPPMK VAAIR----AYT----A--DTYGKRALTEVW------TEQLSTYSEEAGFKALSEAVAAGTVE--------LHALMYTQP DTLTGVPKKVPELMEVCI---GGGTLEQKVEF-----AQSIIGN-EVNL--ADV-IGAGEYADVTAITTGKGTQGPVKRW GIML-RKRKHSRGGKKRH-IGNLGP--WNPH-HVRWQVPQMGQMGYQQRTDFNKRILKIGENGT---------DITPAGG FLHYGLLRNPYVMIKGS-VPGPVKRLIRIR--MKAQIIR-LDGGVA-EEIELPA-VF----A--EAYRPDLIRKAVVALQ STRRQPHGTNPYAGI-----------CSSAVGW----------GSGRGASHVPRLK---NGSRA-AK-VP----QA---- KGGRAAHPPK-VEKILIRDINKKEKQKAFRSAIAASVCEDLVRARGHQFEGAC---Q-VVFEDAF---AGL--------- --TKTSLIV---TRD-------EPLAAAANLAGVD-V---------------VSVNALNTELLAPGAQAGRLTVWTQGAL NWLG----------------------------MTLPAINKLVVHMGVG----ESGERLVKGEEIMRAITGQNPVRTIAKK TQPAFNVRKGAPIGCKVTLRGDAARTFLETSLSILE------KTIDA-SQFDKNGNFSFGIEEHTDYPGMS-----YDPK IGIYGMDINVVLE-RPGIRIARRHIEQKKLPNKQR-VTKDDAIAFVREQLSVEV--MTM-E--KTVTIPEGVQVQ-M--- -E-G--T-LLTITGPKGTLQRDV-RYP-Q--VSVTVDATET--IVV----R-T-DASRKQIV-AMVGTLAAHIRNMCKGV TEGFEYSMKVVFAHFPIQLKLQG-NM--LVIENFLGEKQSRKARI-E-E-GVTAKVS--N-D-EIILTG-INKESVGNSA AHIEHAT------KIRNR---DPR-VFQDGIYIVGKA--MKAKQSRTPRSLGTGTRMACVDNTGARLVQVVSVDG-VRRR QPKMGLGDLATVSVKKGTPD-----------MRRKLEKAVVIRQKKEIRRPNGLRISFEDNAMVIVN-EKNE-PKGTEIK GPVAREV--AERFPKLGSMATIIIMP-V--N---------KRSKYRGS-RTCGGGTHKNRRGAGNRGGRGRAGLNAHRF- -AKFYLEDGG--PVYGK----NG--FNHLDIGTIIANSVATKDGDTITDK---------VLG--SGR-V-T-A-R-FNI- TAKAFSEQAKAKIEAMGGQAMN--LAKKAYTRRKYMGGVPGSKIVQFEMG--NLSQEFPVEISLEVL--ESCQIRHTALE AARIAINRKMMDQVG-RANFHFKIRTYPHHVLRENKQATGAGADRVSEGMRMAFGKAVGTAARVQP-KQKVFTVYTNE-- QYIEKSKDALRHGGYKLPSPARL-VFVPFRRRREGKTDYYKRGKLIVAEQPRMVVRKTNRHIIVQMIVA---EMEGDKTL VTANSA-ELLD-YGYK----GST-SNTPAAYLTGMLFAVK--ALNAD-HPAAILDIGLNRATYGAKVFAALKGAVEAGLD VPHGEEILPADERVKGEHIAAYAPD---------------------RAGDLVENVESAAQTIENV-AKAKANELPCSPKH AIEIAKFIRHKKVDEAIAYLNQVVALKKAIPFKTFNRDVAHKRGLD---KWDAGRFPVKASKGYLKMLESVRKN----A- EYS--GLDGEKLEIIHVTANRGRGQNAFFPRAMGRATPKRRETVNLEIIVRETLRVVTGDTVKVLRGD------FI-GEE GVVDGVDTRTS--KII--VHGVSVTKADGT-------------------EVPRKVDPSNVQ-IIKLNL-------KD--- --PRRAAKL--------------GEVA-----------------MA-------------VE-R--------------K-- ---FVAEGVRKVRVERFL--LRDLK-----RAGYGGMDIARTP-L-GTQVTIYAEKPGIVIGKGGKVVRQLTQDLATTPQ IEVQQVQN---PNYNAQIMAERLANALERGWYFRKAGSNVVRRVMES-GALGCEVVLSGKLTGA-RARVQKFTEGYIKHS GEPSITIVEKGYAIAIKKLGTIGVQVKIIMSRQNTIADAMSALKNAGDCGKPECILEPSSKLLGAMLRIMQDAGYIGSFD MID----D---G----RGGQFRVHLSGR---INK-------C---GAITPRYSV---GLDELEYWETRYLPGKNFGLLIL STSRGVLTHNQARQNGIGGELLGFVY--MQKARIRLTGTDFNKVEMVCDKIREIAERTGVNLAGPIPLPTKRLVVPIRKS PDGEGTATWDRWQMRVHKRLIDI-DADERALRQLMRIQVPKDIGIEIVLGQVITGKVVSDRMLGTIVVGRDYLHYVRKYK RYEKRSSKLHAHNPPC-LQVKVGDIVKIAECRPISKSTTFVVVE--VQKPRRREEFTYHGYRIEELQAMAMNDLLPVMPS RARRKI-VRGLSRDEEHLLGKVRAGDA------------QIRTHLRSMIVLPEMIGKEIEIYSGKEFLKVELQP-ESVFH YLGEFALTRRRVAHG----TAGIGATR----SSK-FVPLK-- >ARCH_Cenarchaeum_symbiosum_A Concatenation of 2 sequences MGKRP-------------------LVRR-------------------------------RGRGGMQF-RAATTGKIARAK YPAFELG-------EQREGTVIDLVHERGRDAPLAKIRFE-DGIVSYVPAVLGTRVGSSMNFGL-K-SE-IRDGNVISVQ NIPDGTTVCNVEKHYGDGGAIVKSAGGNATVFSH--GEGGVVLKLPSGRFSTLNPKNRAMVGTLAGGGVSERPFMSAGG- -KWRRFRSKGRKYP-IVRGVAQAAYVHPHGGGRHQH----VGQSSTVSR----NAPPGAKVGS-IAARKTG-R-AKIKDR HRKFSQPRRGSLAYSPRGRARSMEARIRGWPERLL---A-HAGFKAGCIQIVSIDDREHTPNAGKQLVSLGTVLVTPPLH VLGMR----GYS-------KGHYGRHVKFDV------FAE---VAK-------YIVLRNGRLAETMLGGTAEIYGILGVS PRSAGLEQKRPYIFEAPV-----RGGSMKERFAYLKDLL---GK-TVKA--SDV-LEPGAGVDVAAITKGKGWQGVIQRM GAKR---KQHKSRKTVRE-LGSLGP--ISPQ-NVMYTVPRAGQMGFHQRIEYNKRIMAVGSAGE-------DDAINPSGG YKHFGMVKGDYIVLKGS-VPGTYRRLVKLR--MKAAVLG-LDGSKG-KEITLPP-VF----GT-PY-RRDLIKKAYTILD THHFQPKGTHPTAGM-------DVS-ADSLNPPTGHGQARA-RMKGGGGRR--------RGE---AGEVA----SI---- RGGRQAHPPK-VQKVIHKKINKKEKKLALCSAIAATASKSTVAGRGHIIDGIE-L-P-IVISDDI---ESV--------- --SKASLFV--VGADG------PVIRAVGGFPGVT-A---------------RPARDLSVLDLAPGAEPARLTVYSKAAI ESLA------------------------MAGDMRKITLEKVVLNMGVG----QSGNAVEVAKRALGEISGKKPCGRDAHE TQRDFGVRKGEPIGAAVTIRGEDAGALARRLFEAKGGQVKG-------RSFDDFGNFSFGIGEHIDIPGIK-----YDPG IGILGLDVCMTLS-RPGYGIRKRSKHKARVGRSHR-ITATEAKDFVVREFGVEI-----------------MEAS-L--- -T-G--R-MLHVKGKLGSAHKSF-RKI-P--VGIRIDG-SS--VVL----K-A-EGTRKRDL-AILNTARSIVRNLCEGV GVGYTIKLKVVYAHFPITIKQDG-AM--ILVENFQGERSARKAKI-V-G-GTKVVSK--G-E-DVIVTG-HVLTDVSQTA ANLEQGT------KVKNK---DHR-VFLDGVYVYEKKKGVEEFRPYVTRALPVGARVTCADNSGAKVLEIIMVQT-RVSR LPAAAVGDYVNVVVKKGPAE-----------LRKQVHGAVIIRQKYPVRRLNGVRVAFEDNAAVLTT-PEGE-MKGTDIK GPVAAEA--SEKWPRLANLASMVVMA-T--RN--------RKTRKLRGSRTHGWGQVGQHRASGHKGGVGVSGQL----- -KHHF------SSMLKEDPGHFGHDTHPRDLDDFKKVIDLAAS-----DK---------LLG--GGT-V-S-G-A-YSV- KISRLTASAEEKIKRAGGEV-R--SNGQPYTRKEYIKGKPQSKISKFQNG-----SPGDYDYCVQLLINEKVQIRHMAIE SARLAANKTIEKATG-ESGYFSRLRIYPHVLLRENKMIATAGADRLQEGMRRAWGKAVSLGARVRQ-GQVIYEAHVRK-- EHLEHTKKALKHACVKLPGTPTI-RSRILRRLREEKTNYKKRRSMLMGRRDFVTVHISNENAQVQIHAP---KMDGDVVI ASGHSR-YLAS-KGWK----GSR-KSIPASYLTGYLAGKR--AVKKG-AKSAIMYTGTRRYT--DRISAALKGVSDAGVD VPIDPSTFPPDERISGEHLT------------------------------VKNDVKQIKTVITRH-VRASLREKQISHKH AREISLHIRGMTVEKARDFLQAVIEKKRAVPFRRFKRQVGHRSDP----GVMAGRYPEKSAAEFIKLLDNLESN----A- EYK--GMDLDRLTIVGAVAHKGILIKRFIPRAMGRSTPKNNVLTHVELVARESVRVVEGDTVSVVRGE------YK-DID GKVSHVDTESG--SVA--IEGIDVLIRASK----VV-VTGWRMKLGGTAEPAAKADSEDAA-SVGKAE-----------P --EDSGIDD-------------ATEPE---QAGAAGAESHDA--MT-------------AV------------------K S--VIRENYNMMKLREFL--RENIK-----DSGFSGVEVEKNP-R-GTKITLHVTRPGIVIGRKGVGIRELTERLEKDPQ VDVKEIET---PELYPGVMCNRMASHIERGTAFRRATMWTIQQIMEKKDAMGVQITISGKLRG-DRSAFEKHTSGILPRA GHYADVIVLDDVVHVKTPMGLIGIRIRIAMPATNILANLFVTLYNTEARRRGDCQVYPTSKLGVEVLGTLKKAGYIGEFE HVE----D---S----RGGKFSVHLLAK---ITK-------C---GAISPRFKVKKGE---YTFWEQQYLPSYDRGMLVV TTNQGVMSHHEAAERGIGGFLIGYVY-MTQSARVKLTSINLLKLDGVCGIIMDIGKRTGVRIKGPTPLPVKKLHIATRKS PCGSGTETYEKWEMRMHRRIIDI-SADDKTIRRLIDLKIPDDVHLELFLGKLFEGTIVSAKARSTVVIEKESPVYFTKFK RYARGRSRIHAHVPS--NIVREGDRVLAAECRPVAKSVSFVVVE--VKG--MVKKFEYRGKPAEELESMPLDSLFRLFNS RQRRSL-TRGITDGKRKLIREIKDARA---GKEGN----PIKTHLRDLIVLPSMTGVTVNVFSGKEFRPVEITT-EMIGH YLGEYVITNKRVSHG----APGVGASR----SSL-YVPLK-- >ARCH_Desulfurococcus_kamchatkensis_1221n Concatenation of 2 sequences M----------GKR----------IIPQ----------------------------R--RGKASPVF-KTPDHIHVAPAR YPLLDPSKT--YK-----AVVEDLVHDPGRWVPLAQVKLE-TGLVFYVPAVEGMYAGQIIEIGP-G-AK-PVNGNILPVG MIPEGMQVVNIEKRPGDGGKFVRASGTYAVIVGR--AGGKTQVQLPSGRVIEVPNESRAMIGVIAGGGRLEKPLLKAGAA -YYKWSAKSRVW-P-KVRGVAMNAAFHPHGGGSHQH----VGRPSTVAR----NTPPGRKVGH-IAARRTG-------RR HRKLHAPRHGSLGVRPRKRAEELTPRVKRWPEVLL---G-FPVYKAGMTHAIIVEDRPNTPVTGKEVFTPVTILDAPPIV VLGVR--TYIID----E--EGSPYDAIAKAF-------EE--LLRD----------ALSGEID---------VRVIASTI PVLSGIGKKKPEIIELKI---GGGSIDERLKY-----AEGILGG-YVRA--SDV-FMEGQFVDVIGVTKGKGFQGVVKRF GVKE-LPRWHKHRKGSRK-IGA-----RSPGFGTMSEPPQAGQMGFHRRTEYNKRILKMGLNGL---------EITIEGG FLHYGLVYGPYIMLKGT-VFGPAKRMLILREKIKVNVYG-VNGNVV-GEIELPE-LF----NV-PI-RRDLIRRAFLSAF TAMLQPKGRDPLAGK-----------RTTAKYW----------GVGYGLARVPRLP---NGT---ARFVV----ST---- RKGHAAFPPR-PDERIHEEVNKKERVMAIISALAATSRPELVRERGHVFTPGRL--P-VIIVDEA------ESI------ --SKTTLFI--VSSYS--I---PLAKAVRNLPGVD-I---------------ATPGNLSILHLAPGGVPGRLTVISMKAL NELA-MVMSILTQDV----ESRILEKWN-SNPMLKPFIAKVTVNIGVG----AESDRLPKAMKVLEELTGAKPVPRKAKK TIKDFGIKKGDNIAVVVTLRRGKAIEFLRKVFETIGYRVRE-------SSFDDYGNVSIGVKEHIHMPGVR-----YDPE IGVFGMDVAITIE-RPGYRVMRRKRARSRVPRRHR-VNKLEAMVLLKQLFGVEIMARVF-HVAEKVEIPENVAVE-V--- -D-G--L-RVTVKGPKGIITRDF-SHARG--VFIRLED-RV--VIV----E-T-FVADRKQK-ALVGTIAAHIRNMITGV VRGYRYKLKIIFSHFPITVSVDE-KNKVVRIRNFMGEKSDRIAKI-Y-G-NVKVKVS--G-E-DIIIEG-VDIEEVGLTA ASIERAT------RVTD----RDRRVFMDGIYIYEKGEAPAFSRRRVNTGLQVMSIAKAADNSGAKEVMIIGVPG-RLRR VPPAGVGDLVVVSVKKGIPE-----------MRKKVFKAIVVRQRRPYKRPDGTWVAFEDNAVVILT-PEGT-PKGTEIR GPIAREA--AERWPQIANLASMIV------MVVRKGKKS-RKLQGRT--RTMGWGRVGQHRKSGSRGGFGAVGFH----- -KHKY------IWIIKHAPNWYGKHFRPINVGEL--GKAIIED-GLIVDK---------VLG--SGK-V-T-R-G-LKV- IAREITEEAKRKIEEAGGKVMH--FSGPPYTRKEYIPGVPQPKITKFEMG----NPKLDYDYELALVVEEAGQIRHNALE AARVMALKKLSVDAG-ENNFYLKVKPYPHHVIRENKMMAFAGADRLQDGMRLSFGKPIGTAARVSP-GQEVIVIRVKA-- EHAKIGKEALKIAASKLPLPTRV-IKVPRRRRREGKTNYYKRYRMIVSGHPRFIVRKTLNYIWVQVATA---RPEGDVII AAAHSN-ELRKRFGWK----AGT-CNTSAAYLTGLLAALR--ALEKG-VEYAVPDIGLHRPVKGALVFAAIKAANDAGLK VPMGGEVAPSEERIRGEHIASYAKILR--ENGLLEKRFSRYLANGLQPEDLPSHFEEVKNKISKI-AKAVRYDIPVSIKY MREIAYTLKGMKLNEAIKFLEDVVKMKQAVPFRRYHGKLSHKKGLADRFKWPIGRYPVKGARYTLEVLRNVEAN----A- ENK--GLDKDKLVIIHIAAHKGITLKRYMPRAFGRATPKFRRMSNLEVIVKERLPVRQGDTVRIMRGE------FK-GHE GKVVEVDLKRV--RVF--IEGVQRKKADGS----PV---------------YIPIHPSKVM-IIKADL-----------S --DKRRLEI---IE----------RRK---AGTSSEHSQEVAM-VGPRVKSY---------------------------- ---FLEYGLKKLMIDEFL--AHYFK-----DAGYADVELYRTP-T-GYRVVIHAEYPGRLIGRGGSVIKKLSTILQNKVN ITISPVID---PDLNARVVAFRIVRALEKEIPFRRVMMYMLKRVMDA-GAIGAEIIISGKLRG-ERATYEKLKAGKVYKA GEPVEYMVDRAVVKALLKPGIFGVEVVIVMVVMDTLANALSAIYNAEIRAKKEVVVWPASKLTLNVLKVLQREGYIGEFE YID----D---G----RWGKIKIQLLGR---INK-------I---GVIKPRYPVKHRELAEFPEWLKRYLPAYNIGVIIV STPYGVLSHKEAVEKQTGGVLLAYCYSATRMVKIKIWSTNVKVLDDFVGKITDIVKKTGVKMNGPIPLPTKKLRIRTMKL PHGEGKKKYEKWEMRIHKRLLYI-AEDERVMKQLIRVRIPPEIWMEIEIGVILTGVVAKKKMQRTVVVRHEYLHYVKKYM RYEKRHRNIHAHLPPC-IDVKEGDTVVIGETRPLAKTVAFVVLGVIKRGPVEWRKFKYRGKSLEELLNMSMDELVMLLPA RQRRSL-KRGLTKAQIKLLAKIRKIAR---NPELA-RKAVIKTHVRDMVVLPEMVGLTIAVYNGKEFIPVKITP-EMIGH YLGEFSPTTKKVTHG----EPGLKATR----ASR-FVAMK-- >ARCH_Haloarcula_marismortui_ATCC_43049 Concatenation of 2 sequences --M--------GRR----------IQGQ----------------------------R--RGRGTSTF-RAPSHRYK---- -ADLEHR-KV-EDGDVIAGTVVDIEHDPARSAPVAAVEFE-DGDRRLILAPEGVGVGDELQVGV-S-AE-IAPGNTLPLA EIPEGVPVCNVESSPGDGGKFARASGVNAQLLTH--DRNVAVVKLPSGEMKRLDPQCRATIGVVAGGGRTDKPFVKAGNK -HHKMKARGTKW-P-NVRGVAMNAVDHPFGGGGRQH----PGKPKSISR----NAPPGRKVGD-IASKRTG-R---GGNE MPQPSRPRKGSLGFGPRKRSTSETPRFNSWPSGQPGVQG-FAGYKAGMTHVVLVNDEPNSPREGMEETVPVTVIETPPMR AVALR----AYE----D--TPYGQRPLTEVW-------TDEFHDRTLDVPEDHDPDAAEEQIAHEAGDLGDLRLITHTVP DAVPSVPKKKPDVMETRV---GGGSVSDRLDHALDIVED---GG-EHAM--NDI-FRAGEYADVAGVTKGKGTQGPVKRW GVQK-RKGKHARQGWRRR-IGNLGP--WNPS-RVRSTVPQQGQTGYHQRTELNKRLIDIGEGDE----------PTVDGG FVNYGEVDGPYTLVKGS-VPGPDKRLVRFR--MQATIYD-LDGNTD-GEVDLPD-VF----ET-PV-RSDLIGKAVRAAQ ANRKQDYGSDEYAGL--------------RTPA---------ESFGSGRGQAHVPKQ--DGR---ARRVP----QA---- VKGRSAHPPK-TEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEV--P-VVVSDDF---EDL--------- --VKTQLFV--T---S--D---EPSTAARNLAGAD-V---------------ATASEVNTEDLAPGGAPGRLTVFTESAL AEVA---------------MSSESESGGDFHEMREPRIEKVVVHMGIG----HGGRDLANAEDILGEITGQMPVRTKAKR TVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLA--------ELAT-SQFDDTGNFSFGVEEHTEFPSQE-----YDPS IGIYGLDVTVNLV-RPGYRVAKRDKASRSIPTKHR-LNPADAVAFIESTYDVEV---MP-R--VELEIPEDVDAE-Q--- -D-H--L-DITVEGDNGSVTRRL-WYP-D--IDVSVDG-DT--VVI----E-S-DEDNAKTM-STIGTFQSHIENMFHGV TEGWEYGMEVFYSHFPMQVNVEG-DE--VVIENFLGEKAPRRTTI-H-G-DTDVEID--G-E-ELTVSG-PDIEAVGQTA ADIEQLT------RINDK---DVR-VFQDGVYITRKPNRMEALGADVTQGLEKGSLITCADNTGARELKVISVHG-TKNR HPKAGLGDKITVSVTKGTPE-----------MRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVD-ENED-PRGTELK GPIAREV--AQRFGSVASAATMIV------------MTS-KKKRQRGS-RTHGGGSHKNRRGAGHRGGRGDAGRD----- -KHEF-H--NHEPL----GK-SG--FKRIDVREIEDGGFRVDVRDVVEVK---------VLG--AGQ-V---RHE-LTL- IADDFSEGAREKVEGAGGSVMD--IDKPAYTRREYITGIPGSKIAQHKMG-RKQKDADDYPVQISLIVEETVQLRHGSLE ASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKQATGAGADRVSDGMRAAFGKIVGTAARVQA-GEQLFTAYCNV-- EDAEHVKEAFRRAYNKITPSCRIKVKVPMRRRREARTDYHQRLRLLKSGKPRLVARKSNKHVRAQLVTL---GPNGDDTL ASAHSS-DLAE-YGWE----APT-GNMPSAYLTGLLAGLR--AQEAG-VEEAVLDIGLNSPTPGSKVFAIQEGAIDAGLD IPHNDDVLADWQRTRGAHIAEYDEQL---EEPLYSGDF--------DAADLPEHFDELRETLDTT-AKAMLRERQMSFKH SKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVD---GWDAGRYPEKASKAFLDLLENAVGN----A- DHQ--GFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEENVRVNAGDTVEVLRGD------FA-GEE GEVINVDLDKA--VIH--VEDVTLEKTDGE-------------------EVPRPLDTSNVR-VTDLDL-------ED--- --EKREARL--ESE--------DD----------SA--------MAD------------------------------E-Q Q--FIEDGLQRTQIDEFF--AEELG-----RAGYGGMDVAKTP-M-GTQIVLKAEKPGMVIGKGGKNIRKITTELEDRPQ VDVQEVDE---PDLNARIVADRLANALERGWYFRKAGHTTIDRIMES-GALGAEIVLSGKVTGA-RSRVEKFNRGYVKHN GEPAEEIVDSGVGVAVMKLGTIGVRVKIIMTGNDPFANALSALNNAESVGHLEQTVSPASNEIGSVLEVFYDRGYIDGFS FVD----D---G----KAGEFEVELKGA---INE-------C------GPVKPRYSAGADEFEKWEKRFLPARDYGTLVV TTSHGIMSHYEAREQGVGGQVIAYVY-MSQQARVRLAGTSPEDLDDICADVREIANKTGVELSGPVPLPTKTLEVPSRKS PDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQVPNDVSIEIVLGQTLNGEVASTDMEKTVVVEREYDVKVPKYD RFMKRRSRVPAHAPDC-LDLAVGDTVTIAECRPLSKTKSHVVVGVVADEIGHEGEFSFRGHTLDELQEMELEEVAELLPA RQRRSI-VRGLTEEKHKLLEKAREAGE---EETAN---DPIRTHLRDMPVVPEMVGLTFAVHDGQNFERVKVEP-EMLGH YLGEFQLTRSSVEHG----QAGIGATR----SSK-FVPLK-- >ARCH_Halobacterium_salinarum_R1 Concatenation of 2 sequences M----------GRR----------IQGQ------------------------------RRGRGTSTF-RAPSHRYK---- -AELSHK-RTEDT-DVLAGEVIDVEHDPARSAPVARVAFE-DDDQRLVLASEGVGVGDTIEIGI-S-AT-IEEGNTLPLA EIPEGVPVCNVESHPGDGGKFARAGGVNADLVTH--ERDATIVELPSGETKRLSPDCRATIGVVAGGGRTEKPFVKAGNK -HHKMKARGTKW-P-RVRGVAMNAVDHPFGGGGRQH----PGRPKSVSRDAAPGRKVGDIASK-RTGRGGN-E------- MPQPNRPRKGSMGFSPRKRAESEVPRFNSWPAGEVGLQG-FAGYKAGMTHVVLVDDKANAPTEGMETTVPVTVVETPPMR AAAVR----LYE----D--TPYGKKPLTEVW------ADDTHELSV----------PDEGGDALDTEEIADIRVITHTVP GDTAGVPKKNPDVMETRV-GGGTLADRLEFAA-----DLIEDGG--VHAFGD-V-FRAGEFTDAAGITKGKGTQGPVKRW GVQK-RKGKHARQGWRRR-IGNLGP--WNPS-RVRSTVPQQGQTGYHQRTELNKRLIDINDGDE----------PTPDGG FPNYGEVDGPYTLVKGS-VPGPEQRLVRFR--MQVTVRD-LDGDDA-GTLDLPR-VF----E--EPVRPDLVKRAVLAAQ ANRTQEYGADEYAGL--------------RTTA---------ESQGSGRGMAHVPKANGQGA----R-VP----QT---- VGGRKAHPPK-AEKDHGLDVNDKERKAAVRAAVAATTDSELVADRGHNFDDDVEF-P-LVVSDDF---EDL--------- --VKTQLFV--TASES------GPSTAARNLAGVD-V---------------ATGREVNAEDLAPGAEPGRLTVWTESAV EEVA-------MSET----------DSTDFHEMREPRIEKVVVHMGVG----QGGVELQNAETILEAITGQQTVRTKAKS PEPEFGLRQGDPIGAKVTLRDDTAVDFLERALPAA--------DLDR-RQFDNTGNVSFGIEEHTDFPSQE-----YDPN IGIYGMDVTVNLT-RPGYRVAKRDQGTRQIPSNHR-LNSEDAVSFLVSNFDVEV---MA-R--VEIEIPDDVTAE-V--- -D-H--L-DLTVEGPEGSVTRRL-WYP-D--VDVSVED-DA--VVV----A-S-EVDDAKTD-STVGTFESHVANMFHGV SEGWEYKLEVHYSHFPMQVDVEG-EE--VVIQNFLGEKAARRTQI-R-G-DTDVVVD--D-E-EVTLSG-PSIEDVGQTA ADIEQLT------RVTDK---DTR-VFQDGVYIVEKPAKMEAIKADITQGLEKGSLITCADNTGARELKITSVMG-RKNR HPKAGLGDTITVSVTKGTPE-----------MRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIID-DLGE-PRGTEIK GPISREV--AERYGTIASTATMIV---M--TD--------KKRRQRGS-RTHGGGTHKNRRGAGNRGGRGRAGRK----- --------KHEQHNYEDVGK-SG--FKRLSVQELTEFGYRVDARDVVDVK---------VLG--GGQ-LYE-Q---LEV- TADAFSDAAVELIEGEGGDAMK--IDKPSYTRRDYVTGIPGSKIAQHKMG-DLQADADDYPVQISLVPQEECQLRHGSLE AARLSANRHLIKELG-EGNYKMQLRKFPHQIIRENKQATGAGADRVSDGMRQAFGVPVGTAARIQP-GDQLFTAYCEV-- EQAAAVKEAFRRAYNKITPPCKINVKVPMRRRREVRTDYHQRLRLLKSGKPRLVARKSNKHVTAQLVTT---GPDGDETV ASAHSS-DLDA-YGWA----APT-GNLPAAYLTGLLAGQR--AVDAG-VEEAVLDIGLNTATPGSKVFAIQEGAIDAGLD VPHNDSVLADWSRTRGEHIAEYAESL---DEPLYSGDF--------DATALPAHFDETREAIEAS-AKAMLRERSISLKH SKAIAREISGETVADAKEYLQAVIDEERSVPFKQHNSGVGHRNDID---GWDAGRYPEKASKDFLKLLSNVSNN----A- DQQ--GFDADEMVIEHVAPHKVGESQGRKPRAMGRATTWNATLCDVEIVVTENVRVNVGDTVEVMRGD------DA-GED GEVTDVDLRDA--EVF--VEGVTVEAADGE-------------------ETPRPVESSNLR-VTDLDL------------ ----------------------DDDMR---VERLEG---DNE--MADEL----------------------------E-- ---FIEQGLQRSQIDEFF--AEELA-----RAGYGGMELAPTP-M-GMQIVLKAEKPGMVIGKGGKNIRKITTQLEERPQ IDVQEVEE---PDLNAQIVADRLANALERGWYFRKAGHTTIDRIMES-GALGAEIVLSGKVTG-NRGRVEKFNRGYIKHN GEPAEEIVDHGKGVAVMKLGTIGVNVKIIMTANDPLSDALSGIDNAESVGHLTHTVAPASNMVGSVLEVFYDRGYIDGFE FVD----N---G----KAGRFEVELKGA---INE-------C---GPVNPRYSVGADG---FEQWEKRYLPARDYGSLVV TTSHGIMSHYEAREAGIGGQVIAYVY--MQQARVRLAGVDPDDLDNICGEVQEIADKTGVKVSGPVPLPTKTLEVPSRKS PDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQVPNDVNIEIVLGQVLEGEVASTDMEKTVVVEREYDVFVPKYD RYMKRRSRVPAHAPEC-FDISVGDTVSIAETRPLSKTKSHVVVEITDGGTGREGEFTYRGHDLDELQEMSLEDVAELLPA RQRRTI-TRGLSEEHHKVLAEARESGT---EETAN---NPIRTHLRDMPVLPEFVGLTFAVYTGQEFERVEVQP-EMIGH YLGEFQLTRSSVEHG----QAGIGATR----SSK-FVPLK-- >ARCH_Halobacterium_sp_NRC-1 Concatenation of 2 sequences M----------GRR----------IQGQ------------------------------RRGRGTSTF-RAPSHRYK---- -AELSHK-RTEDT-DVLAGEVIDVEHDPARSAPVARVAFE-DDDQRLVLASEGVGVGDTIEIGI-S-AT-IEEGNTLPLA EIPEGVPVCNVESHPGDGGKFARAGGVNADLVTH--ERDATIVELPSGETKRLSPDCRATIGVVAGGGRTEKPFVKAGNK -HHKMKARGTKW-P-RVRGVAMNAVDHPFGGGGRQH----PGRPKSVSRDAAPGRKVGDIASK-RTGRGGN-E------- MPQPNRPRKGSMGFSPRKRAESEVPRFNSWPAGEVGLQG-FAGYKAGMTHVVLVDDKANAPTEGMETTVPVTVVETPPMR AAAVR----LYE----D--TPYGKKPLTEVW-------ADDTHLSV----------PDEGGDALDTEEIADIRVITHTVP GDTAGVPKKNPDVMETRV---GGGTLADRLEF-----AADLIGG--VHAFGD-V-FRAGEFTDAAGITKGKGTQGPVKRW GVQK-RKGKHARQGWRRR-IGNLGP--WNPS-RVRSTVPQQGQTGYHQRTELNKRLIDINDGDE----------PTPDGG FPNYGEVDGPYTLVKGS-VPGPEQRLVRFR--MQVTVRD-LDGDDA-GTLDLPR-VF----E--EPVRPDLVKRAVLAAQ ANRTQEYGADEYAGL-----------RTTA------------ESQGSGRGMAHVPKANGQGA----R-VP----QT---- VGGRKAHPPK-AEKDHGLDVNDKERKAAVRAAVAATTDSELVADRGHNFDDDVEF-P-LVVSDDF---EDL--------- --VKTQLFV--TASES------GPSTAARNLAGVD-V---------------ATGREVNAEDLAPGAEPGRLTVWTESAV EEVA-------MSET----------DSTDFHEMREPRIEKVVVHMGVG----QGGVELQNAETILEAITGQQTVRTKAKS PEPEFGLRQGDPIGAKVTLRDDTAVDFLERALPAA--------DLDR-RQFDNTGNVSFGIEEHTDFPSQE-----YDPN IGIYGMDVTVNLT-RPGYRVAKRDQGTRQIPSNHR-LNSEDAVSFLVSNFDVEV---MA-R--VEIEIPDDVTAE-V--- -D-H--L-DLTVEGPEGSVTRRL-WYP-D--VDVSVED-DA--VVV----A-S-EVDDAKTD-STVGTFESHVANMFHGV SEGWEYKLEVHYSHFPMQVDVEG-EE--VVIQNFLGEKAARRTQI-R-G-DTDVVVD--D-E-EVTLSG-PSIEDVGQTA ADIEQLT------RVTDK---DTR-VFQDGVYIVEKPAKMEAIKADITQGLEKGSLITCADNTGARELKITSVMG-RKNR HPKAGLGDTITVSVTKGTPE-----------MRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIID-DLGE-PRGTEIK GPISREV--AERYGTIASTATMIV---M--TD--------KKRRQRGS-RTHGGGTHKNRRGAGNRGGRGRAGRK----- --------KHEQHNYEDVGK-SG--FKRLSVQELEFGYRVDAR-DVVDVK---------VLG--GGQ-LYE-Q---LEV- TADAFSDAAVELIEGEGGDAMK--IDKPSYTRRDYVTGIPGSKIAQHKMG-DLQADADDYPVQISLVPQEECQLRHGSLE AARLSANRHLIKELG-EGNYKMQLRKFPHQIIRENKQATGAGADRVSDGMRQAFGVPVGTAARIQP-GDQLFTAYCEV-- EQAAAVKEAFRRAYNKITPPCKINVKVPMRRRREVRTDYHQRLRLLKSGKPRLVARKSNKHVTAQLVTT---GPDGDETV ASAHSS-DLDA-YGWA----APT-GNLPAAYLTGLLAGQR--AVDAG-VEEAVLDIGLNTATPGSKVFAIQEGAIDAGLD VPHNDSVLADWSRTRGEHIAEYAESL---DEPLYSGDF--------DATALPAHFDETREAIEAS-AKAMLRERSISLKH SKAIAREISGETVADAKEYLQAVIDEERSVPFKQHNSGVGHRNDID---GWDAGRYPEKASKDFLKLLSNVSNN----A- DQQ--GFDADEMVIEHVAPHKVGESQGRKPRAMGRATTWNATLCDVEIVVTENVRVNVGDTVEVMRGD------DA-GED GEVTDVDLRDA--EVF--VEGVTVEAADGE-------------------ETPRPVESSNLR-VTDLDL------------ ----------------------DDDMR---VERLEG---DNE--MADEL----------------------------E-- ---FIEQGLQRSQIDEFF--AEELA-----RAGYGGMELAPTP-M-GMQIVLKAEKPGMVIGKGGKNIRKITTQLEERPQ IDVQEVEE---PDLNAQIVADRLANALERGWYFRKAGHTTIDRIMES-GALGAEIVLSGKVTG-NRGRVEKFNRGYIKHN GEPAEEIVDHGKGVAVMKLGTIGVNVKIIMTANDPLSDALSGIDNAESVGHLTHTVAPASNMVGSVLEVFYDRGYIDGFE FVD----N---G----KAGRFEVELKGA---INE-------C---GPVNPRYSVGADG---FEQWEKRYLPARDYGSLVV TTSHGIMSHYEAREAGIGGQVIAYVY--MQQARVRLAGVDPDDLDNICGEVQEIADKTGVKVSGPVPLPTKTLEVPSRKS PDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQVPNDVNIEIVLGQVLEGEVASTDMEKTVVVEREYDVFVPKYD RYMKRRSRVPAHAPEC-FDISVGDTVSIAETRPLSKTKSHVVVEITDGGTGREGEFTYRGHDLDELQEMSLEDVAELLPA RQRRTI-TRGLSEEHHKVLAEARESGT---EETAN---NPIRTHLRDMPVLPEFVGLTFAVYTGQEFERVEVQP-EMIGH YLGEFQLTRSSVEHG----QAGIGATR----SSK-FVPLK-- >ARCH_Haloquadratum_walsbyi_DSM_16790 Concatenation of 2 sequences M----------GRR----------IQGQ----------------------------R--RGRGTSTF-RAPSHRYK---- -AELSHK-QS-ESDDTITGTIVDIEHDPARSAPVAAVEFD-DGDRRLVLAPEGIRVGETMQIGV-S-AE-IKPGNTLPLR EIPEGVPVCNVESQVGDGGKFARASGTSAQLMTH--DRDVVVIELPSGETKRLSPACQATIGVVAGGGRTEKPFVKAGKK -HHKMKARGIKW-P-RVRGVAMNAVDHPFGGGGRQH----PGQPKSVSR----DAPPGRKVGD-IASKRTG-R------G MPQPSRPRKGSMGFSPRKRAESEVPRIRSWASGVQ---G-FAGYKAGMTQVLMVNDEANSPREGMEEAVPVTVVETPPMR AVALR----AYE----D--TPYGSKPLTEVW-------GR---LDL----------PNEDTFDAETGDIDDVRLITHTLP AGMRNIPKKTPDVMETRV-GGGTLTDRVEFGL-----DLISDGG-EHEI--SDI-FRAGEYLDAAGVTKGKGTQGPVKRF GVQK-RKGKHARQGYRRR-IGNLGP--WNPS-RVRSTVPQQGQTGYHQRTELNKRLIEIGNGDE----------PTVDGG FVGYGEVDGPYALIKGS-LPGPDQRLLRFR--METTIHN-LNGDKA-DTLELPA-VF----ET-PY-RPDVIERAVVAAQ ANRKQPYGADPYAGM--------------RTPA---------ESFGSGRGMAHVPRE--NGQ---ARRVP----QA---- VSGRKAHPPK-AEKDQSKSVNTKERKLAFQSAVAATADPSQVEERGHQFENDVEL-P-LVVSDEF---EEL--------- --IKTQLFI--T---S--D---EPSKAARNLAGAD-V---------------VTAANVSAEDLAPGTQPGRLTVYTESAI KEVA---------------MSETDSTF---HEMREPQLEKVVVHMAVG----EGGRELANAEEILQEIAGQTAVRTTATR AASQFGAREGDPIGAKVTLRGADAQSFLEKALPLVT--------ISE-RQFDETGNFSFGVEEHTTFPSQE-----YDPQ IGIYGLDVTVNLT-RPGYRVTKRDKASQPIPSRHR-LTPSDAVQFIESEFTVDI---MT-R--TAIEIPENVSAE-V--- -S-N--L-ALTVEGPNGSVTRTL-WYP-S--VTVSVDE-DADDVVI----E-T-DETDAKTS-ATVGTFESHVSNMIHGV TDGWSYEMEVYYAHFPMQVSVEG-DE--VIIENFLGEKASRRTPI-R-G-DTNVQID--G-E-MVTLTG-PSKEDVGQTA ADIEQLT------RVTDK---DTR-IFQDGVYITQKPQQMEALKADVTKGLERGSLVTCADNTGARELKVISVMG-TKNR HPKAGIGDQVTVSVTKGTPE-----------MRRQVLEAVIVRQRKSIRRPDGTRVKFEDNAAVIID-EMEE-PRGTEIK GPIAREV--AERFGSIASTATMIV------------MTS-KKRRQRGS-RTHGGGTHKNRRGAGHRGGRGRAG------- -RDKH-EQHNYEPI----GK-HG--FKRISVQELDDGAYHIDARDIADTK---------VLG--DGQ-V---R-QELHV- IADAFSDTARTLIEDAGGSAMK--LSKPSYTRRDYVTGIPGSKIAQHNMG-NLQTGPQDYPVQISLRIEEECQIRHGSLE SARLSANRTMLKQVG-QDNYKMVLRKFPHQILRENKQATGAGADRVSDGMRQAFGKPVGTAARIQQ-NERVFTIYCEV-- DDASVAKDGLRRAYNKMSPPCRIDVKVPMRRRREVRTDYHQRLRLLKSGKPRLVARVSNRHVRAQLITP---GPDGDETH VAASSE-HLSE-YGWE----APT-GNLPSAYLTGYLAGMR--AIEAG-LDEAVLDIGLNTATPGNKVFVVQEGAIDAGVS IPHNESVLADWSRNRGEHIAAYAEQR---DEPLYNSDF--------DATTLPEHFDTVLETIETT-ARGMLRDRPISLKH SKAIAREIKGMTIADAESYLDDVIAQRQSVPFRQHNSGVGHRSDID---GWDAGRYPEKASKAFLELIENVASN------ ANEQ-GFDGNAMAIRHVAAHKVGERQGRKPRAFGSADPWNTTICDVELIIEQNVRVNAGDTVEVLRGD------DA-GHE AEVVTVDLTET--VIH--VEDVTIEKADGE-------------------EVPRPLDSSNLR-VTELNL-------ED--- --SKREARL----E--------EGDEQ-----------------MAD------------------------------E-H Q--FIENGLQRSQIDEFF--ADELG-----RAGYGGMDVAKTP-M-GTQIVLKAEKPGMVIGKGGKNIRKVTRELEDRPQ IDVQEVDE---PDLNARIVADRLANALERGWYFRKAGHTTIDRIIES-GALGAEIVLSGKVTGA-RSRVEKFNRGYIKHN GEPAQEIVDEGQGVAVMKLGTIGVTVKIIMTGNDPLANALSGVDNAESVGHLSHEIQPASNVIGSVLEVFYDRGYINGFE FVD----D---G----KAGRFEVELSGG---INE-------C---GAVKPRYSA---GADEFERWEKRYLPARDYGALIV TTSHGVMSHYEARETGIGGQVIAYVY--MQQARVRLAGTSPDDLDDICDDVRDIADTTGVNLSGPIPLPTKTLEIPTRKS PDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQVPNDVSIEIVLGQTLEGTVASTDMDKTVIVEREYDVRVPKYD RLMKRRSRIPAHAPPC-VDLAEGDTVRIAETRPLSKTKSHVVVEQI--DTGREGEFTYRGHTLDELQAMSLEDITALLPA RQRRTI-ERGLTTEQQKLRETVRDADP---QKTAN---DPIRTHLRDMPILPSFVEKTIAVYNGQSFERVRIEP-EMIGH YLGEFQLTRTSVEHG----QAGIGATR----SSK-FVPLK-- >ARCH_Halorubrum_lacusprofundi_ATCC_49239 Concatenation of 2 sequences M----------GRR----------IQGQ----------------------------R--RGRGGPTF-RAPSHRYK---- -AELSHK-KL-EDVDTITGEIVGIEHDPARSAPLAEIEFE-DDDRRLVLAPEGVRVGDTIQVGV-S-AE-IKPGNTLPLA EIPEGVPVCNVESNRGDGGKFARASGVSATLLTH--DRDVAVVQLPSGEVKRLDPQCRATIGVVAGGGRTEKPFVKAGNK -YHKMKARGTKY-P-RVRGVAMNAVDHPFGGGGRQH----PGQPKSVSR----DAPPGRKVGD-IASKRTG-R------G MPQPSRPRKGSLGYGPRTRADREVPRIRSWPDALQ---G-FAGYKAGMTHVVMVNDEANSPREGMETSVPVTVVETPPMY AVALR----AYE----Q--TPYGKKPVEEVW------ATEFHELDL----------PAEDTFLLDEGAVDDVRVITHTVP SELANVPKKKPDVMETRV-GGGSLEERVDFGL-----DLVAEGG-AHEF--GDV-FRAGQYTDVSGITKGKGTQGPVKRW GVQK-RKGKHARQGWRRR-IGNLGP--WNPS-RVRSTVPQQGQTGYHQRTELNKRLIDFGEGDD----------ASVDGG FVNYGEVDGEYALIKGS-LPGPDKRLIRFR--MNATVHD-LDGGDA-GSVELPA-IF----ET-AF-RPDLIGRAVSAAQ ANRKQAYGADEFAGL-----------RTPAESF----------GSGRGLAHIPRS----ENV---ARRVP----NA---- VSGRAAHPPK-AEKDQTKSLNDKERQLAIRSAIAATADAETVAERGHAFDEDLDL-P-LVVSDEF---EDL--------- --NKTQLVV--T---S--E---EPSRAARNLSGVD-V---------------ATAREVNAEDLAPGAHPGRLTLWTESAI EEVA------------------MSESESASHEMREPYLEKVVVHMGVG----QGGEPLADAEEIIEEITDQQSVRTTSKR TIAEFGIRKGDPIGVKVTLRGEDAHAFLDTALELA--------DISK-SQFDDTGNLSFGVEDHTDFPSQE-----YDPN IGIYGLDVTTTIV-RPGYRVSKRDKATASIPSKHR-MTAEDATAFLETNFDVEV---MN-R--VEIEIPDDVSAE-T--- -D-H--L-ELTVEGPNGSVTRRL-WYP-D--VEVTVED-GV--VAI----A-S-ENEDAKTN-ATVGTFESHVANMIHGV TDGWEYTMEVYYAHFPMQVTVEG-DE--VVIENFLGERAQRRTPI-R-G-DTDVQID--G-E-TVTLSG-SDKEAVGQTA ADIEQLT------KVTDK---DTR-VFQDGVYIVEKPT-MEALKADVTQGLSKGSLITCADNTGARELKVISVAG-TKNR HPKAGIGDKVTVSVTKGTPE-----------MRRQVLEAVVVRQRKPIRRPNGTRVKFEDNAAVIID-DLDE-PRGTEIK GPVAREV--AERFGSIASTATMIVMT--------------NKKRRQRGSRTHGGGTHKNRRGAGHRGGRGAAGRA----- -KHEF---HNYGPL----GK-YG--FKRVTVQKLEDGDAYVIDRDVVEVK---------VLG--GGQ-V-R-R-E-LRV- TADAFTAGAVELIEEAGGEAMT--IDKPSYTRREYITGIPGSKIAQHNMG-DLSAEPDDYPVQISLRVEEELQIRHGSLE SSRLSANRHLIKELG-EGNYKMTLRKFPHQVIRENKQATGAGADRVSDGMRQAFGKPVGTAARLNK-DDIVFTAYCDV-- EQASVVKEAFRRAYNKLSPPCRI-TKVPMRRRREVRTDYHQRLRLLKSGKPRLVARVSNAHVRAQLVTP---GSDGDETH AAASSE-ELGE-YGWD----APT-GNLPSAYLTGYLAGAR--AVDAG-LDEAVLDIGLNTATPGNKTFAVQEGAIDAGLE IPHNDDVLADWSRTRGEHIAAYAEQL---DEPLYSGDF--------DAADLPEHFDDVLATIETT-AKGMLRDRPISVKD SKEISREIKGETVADAEEFLQEVIDEETSVPMRQHSAGAGHRSDID---GWDAGRYPEKAAKDFLKLLENVKNN----A- DEQ--GFDGDEMVIKHVAPHKVGERPGRNPRAAGATQ-WNTTLADVELIIEDNVRVNAGDTVEVLRGD------AA-GTE AEVISVDLSAE--RIT--VEDVTVEKADGE-------------------EVPRPIPASNVR-VAELDL-------ED--- --ERREARL--QED--------NE--------------------MAD------------------------------E-H Q--FIEDGLRRSQINEFF--ADELG-----RAGYGGMDVAKTP-M-GTQIVLKAEKPGMVIGKGGKNIRKITTELEDRPQ IDVQEVDE---PDLNAQIVADRLANALERGWYFRKAGHTTIDRIMDA-GALGAEIVLSGKVTGA-RSRVEKFNRGYIKHN GEPAQEVVDHGQGVAVMKLGTIGVNVKIIMTGNDPFTNALAGMDNAESVGHLSYTVEPASNIIGSVLEVLYDRGYVDGFE YVD----D---G----KAGKFEVELKGA---INE-------C---GAVKPRY---SAGADEFEKWEKRYLPARDYGTLIV TTSHGVMSHYEAREEGIGGQVIAYVY--MQQARVRLAGTSPEDLDDICADVREIADSTGVALSGPIPLPTKTLEIPSRKS PDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRVQVPNDVSIEIVLGQTREGTVVSTDMEKTVIVEREYDVFVPKYD RYMKRRSRIPAHVPGVLDSLEVGDEVKIAETRPLSKTKSHVVVENLSGDGREGKEFAYRGHSLDELQEMDVDEVAELLPA RQRRSI-VRGLGTEQQKLLEKVRSRDK---ETTAD---NPIRTHLRDMPILPEFVGVTFSVYNGHSFERVQVEP-EMIGH FLGEFHLTRSTVEHG----QAGIGATR----SSK-FVPLK-- >ARCH_Hyperthermus_butylicus_DSM_5456 Concatenation of 2 sequences M----------GKR----------LIVQ----------------------------R--RGKGSPLY-RSRPWLHPAPAR YPPLTPV-T--LR-----GRVVELVHDPGRWVPLAHIVLE-NGDEFYIPAAEGMYVGQIIEIGP-D-AR-PVNGNILPVG KIPEGTQVYNIEIRPGDGGKLVRAYGTYAIILGR--SGNKTIIQLPSGKVKEVPNDARATIGIVAGAGRLEKPLLKAGAA -YYKWSAKPHVW-P-RVRGVAMNAVNHPHGGGSHQS----PSFPTTVSR----NAPPGRKVGH-IAARSTG-------RR --------------------------MKSWPELPL---A-FLAYKVGMTHVYVIDDEPGSITHGREIFMPVTVLEAPPMV VTAVR----VYG----Y--DPN--IG-LYTL-------SE--AAVK----------KLEGLLK-----VYDVRIIAATQP RLVGGLSKKKPDLLEIKIGGGSSIEDRFNYAV-----KLL--GS-ELKV-SD-V-FREGQFVDVIAVTKGKGFQGVIKRF GVKE-LPRWHKHRKGSRSGPGTRG-P-ATSF--SWSEVPQPGQMGFHRRTEYNKRILKIGDNGL---------EITPAGG FLHYGIVRSTYILLAGS-IPGTPKRPIVLRQPPRVPVYN-LEGSVA-EEVQLPR-VF----GL-PV-RIDLIRRAFLSEF TARLQPKGRDPLAGK--------RT-TA--RSF----------GVGLGIARVPRI----PGL---GR--A----AFINSA VGGHLAHPPR-VEKKIHEEINKKEKKLATASALAATARKEFVEKRGHRFPA---QTP-VIVVDEV--ETSI--------- --TRVKLFI--VSNHN--S---SFARAVAGLPGVD-V---------------AEPWNVNVLQLAPGGVPGRLTVITRSAL EELGAAVTTQARIPLTPEQIEEIHRKWD-SNPMLKPRIVKVTVNIGVG----ESGERLQKAIKVLEMLTGQKPAVRKAKK TIRDFGIRKGEPIAAMVTLRGEKAIEFLKRVLPAIGNKLRE-------SQFDEFGNVSFGIKEHILIPGVR-----YDPE IGVFGMDIAITIE-RPGYRVMRRRRARSRVPRRHR-VTKEEAMLLLHELFGVSIKAVYV-A--EEVRVPEGVEVS-I--- -D-G--L-KVTVKGPKGELTRDF-SHARN--IVIRLDE-DEEKVVV----E-A-YFANRRVK-ALVGTIAAHIENMITGV TKGFRYKLKIVYSHFPVTVKVQG-DK--VVIENFLGEKAPRIAKIMP---GVTVKVQ--K-D-DVIVEG-IDIEAVGQTA ANIEQAT------KVKD----KDRRVFIDGIYIYEKGVAGAGPRRHIAAGLQVGSYVKVADNSGAKEAMIIGVIG-RLRR IPPAAVGDMVVVTVKKGTPE-----------MRKQVVRAIVIRQRRPYRRPDGTWIAFEDNAVVIVS-PDGT-PKGSEIR GPVAREA--AERWPKVANIASIII------MVVRRRK---KSRHLRGRTRTMGWGRIGQHRGSGSRGGFGAAGMHKHM-- -WTWV-V--KYAPTWF--GK-HG--FNRINVGELLREGVAKQEEGKIVAK---------LLG--RGK-I-T-R-P-VKV- IVPAATERAVKKIEEAGGEVMKRKFSGPPYTRKEYIHGVPPPKIQKFVMG----NPHGDYDYIVEVYVTERGQIRHNALE AARVAVHKYLSTTIG-DQNYFFRVRVYPHHVLRENKMMAFAGADRLQEGMRQAFGKPVGTAARVYP-GQAVLEVRVKK-- EHLDHAKEALRRGASKLPLPSRI-RKVPRRRRREGKTNYYKRYVMVLSGKPRFVVRRTNQYIWVQVIIA---KPQGDVTV AAAHSR-ELVKKYGWL----GGT-KNTPAAYLTGLLAALR--ALKAG-ITYAVLDIGLHRPTRGARVFAALKGALDAGLE IPHSEEVLPEEYRIRGEHIAKYAAMLKEQNPELYEKRFSLYLARGLNPEDLPQHFEEVKNKIEKS-AKAMVWDAPISYKK IVELARLLKGMKVDEARRFLERVARGEEPIPVRRYSGKQAHHRGLAAKYKWPIGRYPVKAAKILLRLLDNVTNN----A- EVK--GLDTERLRIVHIAVHKGRVLKRWMPRAFGRATPKFKKYSHIEIVVAESLPVRVGDEVVIMRGD------FK-GHR GKVVRVDLRRM--RIF--VEGVTITNARGE----PR---------------YYPIHPSNVM-IVSLNL-------DD--- --ERRRQII-------------ERKRRELLMKAAAGGSAEAI--M--------------VLIK----------------R Y--FIKKAMVQTQIDEYL--AKRFY-----RAGYAGVQIIQFP-L-GTRVIIYAERPAMIIGRRGETIRQLAAIFEHEPQ ITVRRVEN---PDLNARVVASRIAVLLERGAYYRRVANVMARRVLNA-GAIGVQIVISGKLR-TERARYEKVRRGKVYTT GHQVEYMVDRAVMHVTLKPGVLGIEVMIVMVMLDTLANAMAAIVNAEMRAKPEVIIMPASKLIANVLRVMQREGYIGEFE YID----D---G----RWGKIRVRLLGR---INK-------A---GVIKPRFSVKYKDLIRMPDWLRKYLPSRDIGILII STSQGVMSHREAIQRRIGGVLLAYVY-MVQKAEIKLWSTNVESLNQVVEQIKAIAKKTGVRMRGPIPLPTRRLIVPTLKL PHGEGSKKWDKWELRIHKRLVIL-DADERVIRQIMRVRVPEDVYIEIRLGLILTGVVIKNKMKNTVVVEREYLYYDRKYK RYERRRSRIHAHNPPC-INAQPGDIVIIGETRPLAKTVHFVVLGVVGKKPPEWKKFRYRGYTLEELLAMPMDQFIKLLPA RQRRSL-LRGLTDAQRRLLWKIRKARQKMLQGKKV----VVKTHVRDMIILPEMVGLTIAVYNGKEFIPVKITP-EMIGH YLGEFSPTCKQVQHG----EPGLKATR----STL-HVALK-- >ARCH_Ignicoccus_hospitalis_KIN4/I Concatenation of 2 sequences M----------GKR----------LRVQ----------------------------R--HGRGTPQW-RNRGHLRVAPGR YPSPEVL-K--LD-ETYEGYVVELKHDPGRWVPLAHIVIP-NVADFWIPAAEGMYTGQKVQIGP-N-AA-PVNGNILPLY AIPEGTQIFNVEIRPGDGGKLARSGGAYAILVGK--SGNSAIIQLPSGKVKQVNAKARATIGIAAGAGRDEKPLLKAGNA -YYKWKAKAKKW-P-VVRGVAMNAVNHPHGGGNHQS----PGYPTTVAR----NAPPGQKVGH-IAARCTG-RGKQAKAR ARKKEAPRRGSAGLRPRKRAASIVPRVRSWPSKPL---A-FLGYKVGMTHVIMIDDREHVDTAGQEIFVPVTVIETPPMV VLGAR--VYGYD----P--NRNPSDTIKEKL-------GEEVLMSKRLPHMVEELGPGKGFEDVDPEKVVGVGLIMSSIP FLAGGVSKKAPDILEVKV----GGSPVEALEY-----AKGKLGQ-LVDV--EEV-IEAGKFVDVIGVTKGKGFQGVIKRF GVKE-LPKWHKHRKGSRR----VGARSWGKG--TSSYVPQPGQMGYHRRTDYNKRVLMISDDPS---------KINVEGG WLHYGLVKSKYVVLKGS-VFGPPKRPIIMRNDLKRHVWD-LNGNPV-EEIELPP-VF----SL-PV-RKDLIRRAFLSAF TARLQPKGRDPMAGK-----------RTTAESL----------GPGHGLARVPRI----KGT---SR-AA-----FVNSA RGGHLAFPPR-PDKKLHEEINKKERLIAIASALAATSRRELVEARGHAISSVKEV-P-LIVVDDI---ENI--------- --EKAKLII--VSTEE--A---PVRRAASAFPGTD-V---------------VAVNLLSVKHLAPGGVPGRLTIISKKAL EEIGKRLEVPLPPER----VEEILKRWE-QQPMLKPRLAKVTVNIALG----ESGERLEKAYNLLEELTGQRPVKRKAKK TIRQFGIRRGENIAVMVTLRGQRAVEFLKKALEAVGWKIKA-------SSFDEFGNVGFGIREHIQIPGTR-----YDPR VGIFGMDVILTIE-RPGYRVARRRRARSKIPRRHR-VTKEESMVFLAKEFGVKIMAKAV-WVHALVDVPEGVEVE-V--- -E-G--S-KVKVRGPKGELERDF-SHAKG--IRIRVVE-EEGKVLV----E-T-FFANRKRK-ALVNTVAAHIKNMITGV TKGWRYKMKIVFSHFPISVKVVG-DR--VEIHNFIGEKAPRVAKVLP---GVTVKVQ--G-R-DVIIEG-TDIEKVAQTA ANIEQAT------KITEF---DRR-VFMDGIYIYAREVMANKSRRKVVTGLQVGSYVKVTDNSGAKVAMIIGVPG-RLRR IPPAGVGDMVVVTVKKGTPE-----------MRHQVVRAIVVRQRKPFRRPDGTWVAFEDNAVVIVS-EDGT-PRGSEIR GPVAREA--VERWPRIGNVASIVVMV-V--RRRR------KSRKLRGRTRTMGWGRIGQHRRSGARGGFGRAGMHKHF-- -WTWV-T--AKSPG--YFGK-YG--FHLINVGELDELARKLNT-NVIDNK---------LLG--FGK-V---KGS-YTV- IVAFASKKAIQKVKAAGGKV-KRKFSGPPYTRHEYIHGIPQPKVVKWVMG----NPHVDADVEVRLVALERAQVRHNALE AARVMVHKNLSSDIG-ESNYVFIIKRYPHHVLREHKFMAFAGADRLQEGMRHAFGKPAGLAARIYP-GMDILVVRTKK-- QYVDKVKEALKIAASKMPMPCRIEVKVPRRRRREGKTNYYKRYTMALSRKPRFVVRKSNKYVWVQVIEF---APEGDKVI AAAHSK-ELEKKYGWK----GYG-NSLPAVYLTGMLAALR--AKKAG-IQYAVPDIGLHKPTKGARVFAAIKAANDVGLE V-PVGDVVPDESRIRGEHIASYAESLKNENPEEYQRRFAKLLERGLKPEDYPKHFEEVKAKIEKT-AKAMMWDAPISPKE ATELARVIRGMKLTEAKAYLERVIKMEEPVPYRRYHGKVAHKRGLADKHGIPMGRYPVKAAKYFLKLLKNVEAN----A- EFK--GLEVEKLKIVHIASHKGMTIKRWMPRAFGRATPEFERRTHLEVIVEERLPVRKGDTVKIVRGK------FR-GHE GTVAKVDLKKA--RIY--VDGATIENSRGE-------------------QRFYPIHPSKVI-ITKLGE-----------V --DKVRQKI---IE----------RRK------------KEV--MS-------------VAKK--------------NKK Y--FLEQALTQVKVDEYL--AYKFH-----SVGYSKVELQKTP-M-GTRVIIYAERSGAIIGRRGQTIKQITKVLEEWPQ VTVVKVEE---PELDARVMAFRLANALQRGFHFRRAAYTTLRRIMGA-GAIGAQVKVSGKLRG-ERARFEKYIAGKVYKS GNQVVRLTDRAIAHVLLKVGVEGVEVIISMVMLDTLANALTTIYNNEVRGNKEAIIMPASKLIANVLRIMQKEGYVGEFE YID----D---G----RWGKIRVRLLGR---INK-------C---GAIKPRVSVSYRDLLVLPEHLRRFLPSKDVGILII STSQGLMTHKEAIQKRVGGIAIAYVYPPKNMARIKMWSTDVKSIEEVAKQIREIAERSGVEVRGPVPLPVKRLEISTLRL PHGEGTKVFDHWEMRIHKRLIDV-ELNDKVMRNIMRIRVPSNVYIEIQIGTILEGVVVKKKMNKAVVVRHEYLYYNRKYQ RYERRKSNIHARLPPCLDEIKEGDVVVIGETRPLAKSISFVVLG--KKAPAAWKKFRYRGKTLEELLEMPLDDFIELLPA RQRRSL-KRGFNDAQRRLLEKVLKARKEMEKGKKV----KIRTHVRDMVILPIMVGLTIEVYNGKEFVPVKIVP-EMIGH YLGEFSHTTAVVKHG----EPGLKATR----SSL-FVAAK-- >ARCH_Metallosphaera_sedula_DSM_5348 Concatenation of 2 sequences MGKKL-------------------LQQR-------------------------------AGRGNINF-RNPGWLRVGKVR YPTITGH----HI-----AKVVDILHNPGMTEPVAKVKLD-TGIQFFIPAVQGLISGQKIEVGE-G-SP-ASLGNIVPAK DLPEGVYVSNVELHRGDGGRYARTAGSYAIVVGK--SEGKVILRLPSGKIKEIDENALVTVGTVAGGGVLEKPLLKAGNN -YWKYKVKATKW-P-DVRGVAMNVVSHPHGGGLHQS----VSRSSTVAR----NTPPGRKVGH-IAARRTG-------RR HRKLSSPRRGSAGLRPRKRSEELLPSPRSYPEVTL---G-FVGYKVGMTHIFMIDEDRSSSMFGKEIYVPVTVLETPPIY VLALR--AYGLN----N--RGE--HSVMGEV------WGDLGDIDK----------EKKEHQESNLESVSYFRLLVSTQP HLIPALGKKTPDIVEVQI---GGGNTKNQLEY-----GLKLLGN-TLSV--RDV-FKEGQLMDIIGVTKGHGFQGVIKRY GVQE-LPRWHKHRKGSRK-VGTKGPSLGTPS-----YVPQPGQMGFHRRTEYNKRILKISDDTK---------LINPKGG FVRYGLVKNTYLLVQGS-TIGSIKRPLFLRLEKSTKVLD-LSGNKV-KDVQLPL-IF----SY-PV-RKDLIRRAFHSSF TQGLQPKGRDPMAGKRTTAKSFGINLGLARVP----------RIRGAG-----------EGA---L--AP----NT---- AGGRLAFPPS-PRERVKEDINEKEKRLAVISALASTTIKEIVTNRGHRFTGDL---P-LVVVDDL---GGI--------- --KKTALLV--VHDPK--L---PIVEAALNLPGVD-V---------------VSAKDVSVIHLAPGGHAGRLVIYTESAL KVLQ-------MEQV------------TKQNPMRNVRIAKVTVNIGLG----ESGERLQKAYQLVEELTGAKPVYTKAKK SIKEFDVRKGAPIGVMVTLRDEKAEEFLKRVLAAVNYKIKA-------SSFDKHGNVSFGIAEHVVIPGTR-----YDPE VGIFGLDVAITFE-RPGFRVSRRKRQKSRIPDSVR-VRKEEAMKFLTENFGVTIMQMVSFR--EEIQIPSGITVN-I--- -D-G--K-TVKVKGKKGELSRDF-SFAKF--LTISLED-GK--IIL----E-G-SFLGRREK-ATAYSIVKHIKNMFTGV QNGYRYYLKIIFTHFPITVKVVN-DE--VQITNLIGEKNVRVAKIMP---GVKVTVK--G-E-DIVVEG-IDLEKVSQTA ANIETVT------KIRDF---DRR-IFSDGIYIYKKEVIVLGSRKGLTPAVQNYTMVNVSDNSGAKEAMIISVFG-ALRR VPYANVGDLVMVSVRKGAPD-----------VRKQKFKAVVIRQRMPFRRPDGTWISFDDNAVVIVN-PDGT-AKGTEIR GPVAREA--AERWPKVASLATLIV------MVVRRAK---KSRKMRAH-RTMGWGTKGQHRDRGAEGGRHVGMHKEK--- -WSWI-VKYGKDWY----GK-HG--FVNISLRKLIQVTNKDGK-LEVDDK---------LLG--GGQ-V-K-A-P-LIV- KVAVATNKAKEKIEKSGGQVMH--FSGPAYTRKEYIPGVPQPKITKFTMG----DHKKDYDFEVRLLTKQIGQIRHNALE AARVIALKQMTSMVGNETDFYLYVTKYPHHVIRENKMMAFAGADRLQDGMRLSFGKPIGTAARITKLGDLIMAIRVKK-- EHLEFAKKAFKVASSKLPLDTEIVVKVKYRRRREGKTNYYRRYTYVLNRSDRVVVRLTNKYVIVQFVKF---DPKGDITV AAAHSR-ELMK-FGWK----GDE-NNSTACYLTGYLAGLR--AKKAG-MTSASADLGLFTPTKGARIFYVLKGVIDSGVK V-PMGDVGVNNDRLAGKHIAEYAKKLEQEDPDKYRGLFSRYLARGLDPKDLPAHFKEVLNSISRV-GKAVIRNAPVSIKD LYNVCKAIRGMNVKEAQAFLQRVMEEKEALPYWRYDHGASHKSNISRKWKVKSGRYPKKAIKYVNKALENALAN----A- QGK--GLDEDKLKVVHIAAHKGIIIKRFMPRAFGRATKKYNRTSHIEVIVGERIGIRKDDTVRVMRGD------NY-GFE GKVTQVFPESG--RIA--IEGLTRKKADGT----PV---------------YIKIHASKVE-ITKLNT-------ND--P RRKDIINRK---------------ASR---QKEEQG---GKA--M--------------VDIK----------------K Y--FLQKSMTRVMVDEFL--AKEYY-----NAEYAGSEISKTP-M-GTRVTIYAGRPAIIIGKDGKTIKRLAQILEKYPQ ITVTQPEK---PELNARVMAFRLAVTLEKGYHFRRAAFMTIRRIMNA-GALGAEVIVSGKITS-ERAKFEKLKEGIVYKT GNNLDVMVDRAIAIATLKMGIYGVEVVITMTVINTLSNALSSLYNNEMRRNKQAIIMPSSKLIVNVLRVMQKEGYVGEFE YID----D---G----RWGKILVQLMGR---INK-------C---GAITPRYSLTYREMISLPDYIRRYLPSKEIGVIIV STPKGVMTHKEAARQRTGGIVLGYVY-MPNKARIRLWSTNVNNLNYVVNQIKGIVDKTGVSMRGPIPLPTRRMEVPVMRL PHGEGRKKWEKWEMSLHKRIIDI-SADERVMRQLMRVKVPEDVYIEIQLGTLIEGTLVKNRAPKMGVIERTYLFYDHKYK RYERRTSRIHARVPSC-LDVKEGDRVIIGETRPLSKSVSFVVLGKR---PAEWKKFRYRGKSLEELLNMPMDDFIKLLPA RQRRSL-RKGFTPSERTLIEKIRKIRR---DSKAD---KPIKTHVRSLVILPEMVGLKFAVYNGKQFVEFQVVP-EMIGH YLGEFSIPIQKVEHG----EPGLKATR----SSL-FMAMKG- >ARCH_Methanobrevibacter_smithii_ATCC_35061 Concatenation of 2 sequences M----------GKR----------LIIQ----------------------------R--RGRGTPAH-RVASHRFKDKIR YRSYDAL----EKEGSIKGIVTDIVHDPARTAPIAEVKFE-NGEKKFILAPESIQIDDEIECGI-S-AP-IKFGNTLPLA EIPEGTPIYDIENTPGDGGRFVRSSGTYASLITH--DANQSVVELPSGELKYLNPRCRASIGVVAGGGRKEKPFLKAG-N -RWHAYKAKGKK-FMTVRGVAMNAVDHPHGGGNRQH----PGRPTTVSR----HAPPGRKVGS-IAAKRTGKR------- MVRHHQPRKGSVAFSPRKRAAKETPRIKSWPQKLL---G-LAGYKVGMTHALVTDSDKNSPTNGMDVFTPVTVLEVPPVV VMGIR----AYE----KTSRGL--KVITEVL-------ADNLDAIA----------KIQGVLK------TEDIKVLVHTN PKVTSVPKKKPDIFECGI-GGANPEEKLNTAL-----ELL--GN-EVKA--SDI-LNEGQFVDAIATTKGKGFQGVVKRW GIRI-QYGKAVRAGKGRH-VGSIGP--WTPS-RTMWTVAQAGQMGYHKRTEFNKKILKIASADE-------VDQINPDGG FVKYGLVKNDYVLVKGS-LPGPSKRLVILR--MKANVYS-MEGEVK-EEIELPA-IF----NE-EY-RPDLIKRAVISAQ TARVQPWGNDPEAGK-----------RTSAKGW----------GSGRGTARVPRIK---NGSK--AAFVP----MA---- VGGRRAHPTR-AEKNHHEKINIKERRFAIRSAVAATANKELVENRGHRLGDLEQV-P-IIVEDDI---CSV--------- --KTTKLLV--VGEDN------GIKLGARNHAGVD-V---------------VTVENLNAELLAPGTHPGRLTIFTKSAV EKLG-------------------------MNPMNEVQISKATVSIGVG----EAGEKLSRAITLLEQMFDQTPVKTFSKV TNPEFGIRKRQPIACKLTLRGEKA----DKAIEMVLEGIN--KNIKP-TQFDAQGNLSFGIKEHIDIPGMK-----YNPD IGIFGMNVSVTFE-KPGYRIAKRRIQQKKVPAKHR-ISKEETMKYMEDNFNVNYVAAAI-R--EEIEIPEGVEVI-I--- -N-N--N-EVTVKGPNGEDSRKF-TYP-N--VDITEVE-NN--VVL----E-T-SFPRKKDK-AMIGTTKAHISNMITGV TDGFEYHMKIVFAHFPMTVKVNK-DV--VVIDNFLGERHPRTAKV-V-G-SAKVVVK--G-D-EVTITG-INKEHVGQTM ANLEQAT------KIKGR---DPR-VFQDGIYLISKE--MKALTSNVSKALPIGATLQCVDNTGAREIQIISVKG-VRRR LDVAGVGDLVVASVKKGTAD-----------MRREVVNAVVIRQKKEYMRADGLRVKFEDNAAVIIT-PEGI-LKGSEVR GPVAKEA--ADRWPSVGSAASILV-------MIRSKR---KINKLRGS-RSNGGGCTKKRRGAGNKGGRGNAGASKQH-- -WTWT-A-K-FDPDHY--GK-HG--FKRVNLSYLDGDSIVIDV-TEL-DK---------VLA--KGK-I-T-K-S-FII- SAPQFSASAIEKIEEMGGEA----------TRRDYIRKTPNSRIVQYDMG----NLTDEFPVSVSLAVKKPAQIRHNSLE AARIASNRLMQRKAG-RLGYHLKLRTYPHQIVRENPMATGAGADRVQSGMRNAFGKPISVEAIVKA-GQRIITIDTNK-- KNFEDAKLALKRAGMKLPVSCRI-VKVPFRRRREGKTDYAARMKLVDYDKSRLVVRLSNAHATVQVIDY---APEGDITL ASAVSK-QLAN-YGYL----GGA-SNTSAVYLTGYLCAKR--ALAKG-VDSAILDIGLKSAIKGSKVFAALKGAVDAGLD IPYGEAVLPDESRINGEHVANYAESL---DDDEIAKLFSKYLERGLQPADLPKNFEETKKNIAKT-ARAMAKSLKISPKH CVEICNAIRGMEVTKAKNYLEDVIDMKKSVPFKRHNRQVGHRKGQE---GWAAGRYPVKAAEQVLKVLENAEAN----A- EYK--GMDTENLFIEHISSHRGVVLPGVIPRAFGRMTPFNTPTTHIQIVLQESLPIRKGDKVQVLRGD------FK-GHE GAVLGVDYGSY--KIT--IEEVTLSKPDGT-------------------AVFLPVDPSNVM-IIDADM------------ ----------------------DDDRR---IKNVTG---DN---M--------------IE-K--------------D-- ---FVTEGLKRTRIDEYL--EKELE-----RAGYGGMDVQITP-L-GTMVVVYAERPGMVIGRGGKNVRAITNTLKNDPQ IEVKEVSV---PELNPKIMAYKIANMLQRGMHFRRVAYSTIRRIMGA-GAQGVEVTISGKIRGS-RSAVAKFVEGYIKKC GEPSIRLVEEGFATVQLKPGVLGIYVRIMMSLMDPLADALTNIRNNELQVKDSCVISPASKLIGEVLSTMQKENYIGNFE YID----D---N----RAGQFKVELEGN---INK-------C---GVIKPRHAVKKDE---FEKFEKRYLPAKNFGILIV TTPEGIMTHYEAKERGIGGRLLAYMY--MHQARIKLTGTDPEKLAYVCDQLKKIAERTGVDLSGPIPLPTKKLVVPTRKS PDGEGKASWEKWELRIHKRLVGI-GADERAMRQVMKVNVPDNVSIEIELGQVLEGIVVSNKAERTISVERSYYKFIKKYE RYEKRKSKINVHKPDC-LSVNVGDSVKVAECRPLSKTKHFVLVE--VKG-MARKIFKYKGYTLEELQDMSLEEVMELFPA RQRRSL-KRGFLPRQQIVLDKMRKLNK---EGSKDGRPVVIRTHCRDMIVLPEMVGTTFGIYNGQNFVEVTIEP-EMIGC YFGEFAPTRQKVQHG----DPGMGATR----SSM-FVPLK-- >ARCH_Methanocaldococcus_jannaschii_DSM_2661 Concatenation of 2 sequences MGKRL-------------------ISQR-------------------------------RGRGSSVY-TCPSHKRRGEAK YRRFDEL----EKKGKVLGKIVDILHDPGRSAPVAKVEYE-TGEEGLLVVPEGVKVGDIIECGV-S-AE-IKPGNILPLG AIPEGIPVFNIETVPGDGGKLVRAGGCYAHILTH--DGERTYVKLPSGHIKALHSMCRATIGVVAGGGRKEKPFVKAGKK -YHAMKAKAVKW-P-RVRGVAMNAVDHPFGGGRHQH----TGKPTTVSR---KKVPPGRKVGH-ISARRTG-----VRK- GLNINRPRRGSLAFSPRKRAKRPVPRIRSWPEDTVRLQA-FPVYKAGMSHAFIKEDNPKSPNAGQEVFTPITILEAPPIN VCAIR----VYG----RNERNYLTTLTEVWA-------DNLDKIKL----------PKKEDRLEALKDKIEDVRVLVHTN PKLTCLPKKKPEILEIRI-----GGKDIEERLNYAKEIL---GK-QLNI--TDV-FQEGELVDTIGVTKGKGFQGQVKRW GVKI-QFGKHARKGVGRH-VGSIGP--WQPK-MVMWSVPMPGQMGYHQRTEYNKRILKIGNNGD---------EITPKGG FLHYGVIRNNYVVLKGS-VQGPAKRLIVLR--MKAVVYN-LNGEAV-KEIDLPA-VF----EE-EY-RPDLIKRAFLSAF TARLQPKGSDPLAGL-----------RTSAKNI----------GKGHGRARVDRVP---QGW---AARVP----QA---- VGGRRAHPPK-VEKILWERVNKKERIKAIKSAIAATANPELVKERGHVFETENL--P-IIVESSF---EEL--------- --QKTKLVV--VGDK---C---NAILASRNLPGVD-V---------------ITAKDLGIIHLAPGGVAGRLTVWTESAL EKLKMSFEELW-----------------QKNPMLKPRIEKVVVNFGVG----ESGDRLTKGAQVIEELTGQKPIRTRAKQ TNPSFGIRKKLPIGLKVTLRGKKAEEFLKNAFEAFQKEGKKLYD----YSFDDYGNFSFGIHEHIDFPGQK-----YDPM IGIFGMDVCVTLE-RPGFRVKRRKRCRAKIPRRHR-LTREEAIEFIEKTFGVKVVAAYI-E--ERVKIPENVQVE-I--- -N-N--N-EVVVKSGGKELRRRF-EHP-K--IVIKKEG-DE--IVI----F-C-EYPRRKDK-AMVGTIRAHINNMIKGV TEGFTYKLKIRYAHFPMKVSVKG-NE--VIIENFLGEKHPRRARI-M-E-GVTVKIS--G-E-DVIVTG-IDKEKVGQTA ANIEQAT------RIKGR---DPR-VFQDGIYIVEKAGKMKAIGSKPVRALPVGARCICADNTGAKEVEIIAVRG-VARR LPTARVGDMVIVTVKKGTPE-----------MRKQVLPAVVIRQRKEIRRPDGTRVKFADNAVVIVT-PDGN-PKGSDIK GPVAKEA--AERWPGIARIAKIII-------MIRKKK---KVKKIRGS-RTCGGGSHKKRRGAGNKGGRGMAGGHKHK-- -WTWI-I--KYCPD--YFGK-YG--FKRINVGELDKFEKEDDK-FVVDEK---------VLG--KGK-V-T-I-P-MIV- KAVEVSEKAREKIEAVGGEVAD--VDKPPYTRKEYVKGVPQPKVVHFIMG----NLSAEFPVKVNLVATRPIQIRHNALE AARVAANKYLTKMCG-RMGYKFQIRVYPHQILREHKMATGAGADRISDGMRLAFGKPIGTAARVKE-GQAILTVWVNP-- DKFPAAKEALRRAAMKLPVPCRI-VRVKFRRRREAKTDYRKRLKLLLSRKPRLVARRTLNHCIAQIVLY---DEKGDKTV VSAHSR-ELIK-LGYK----GHT-GNLPSAYLTGYLLGKK--ALAKG-YTEAVLDIGLHRATKGNAIFAILKGALDAGME IPHGEEILPSEERIRGEHIKAYAEMLKEQDEERYKKQFSKYLEKGLEPEKLPEHFEEIKAKIEKT-ARAMGRNIPISRKH AREICKSINGMKLDEAIKFLEDVIAMRRPVLFRRHCKKVGHRKGKL---GWPAGRYPVKAAKAILKILQHAKAN----A- EYK--GLNTEKLRIKHISTNKGITIKRYMPRAFGRATPKFQETVHIQVILEEAIPVRKGDVVRIMRGD------FK-GLE GEVIKVDLKRY--RIY--VEGANNKRQDGR-------------------EVPYPIHPSNVM-IIKLYD-----------K --DEKRFKH---IK--------NE--------------------M--------------IE-R--------------T-- ---FVKENVKRLLIDEYF--KKELS-----KAGYSHCDIRKTP-I-GTKIIIYAEKPGFVIGRRGSRIRELTETLAKEPQ IDVKPVEN---PDLDAQVVAQKVAQSLERGLHFRRVGHTAVRRVMNA-GAKGVIVIISGKLTG-ERARTEKFMAGYMKHC GEPAEELVDKGRAIAKTKPGVIGVTVKIMMSLMDPLANALNHISNCERVGKKVVYIKPASKLIGRVLKVMQDNGYIGEFE FIE----D---G----RAGIFKVELIGK---INK-------C---GAIKPRFPVKKFG---YEKFEKRYLPARDFGILIV STTQGVMSHEEAKKRGLGGRLLAYVYESMQRARIKLSSTDHKVLDEICRQIKEIAEKTGVDISGPIPLPTKVLRVVTRKS PDGEGSSTFDRWTMKIHKRLIDI-DADERALRHIMKIRIPDNVQIEIQFGQSFVGVVVSDKPHKTVIIKREVVKYIKKYE RYERRTTKLAAHNPPC-IHARVGDIVRVMECRPISKTKAFVVVEKLGRIISKKIEFRYRGYTLEELQQMPLREFAKLLPA RQRRTL-LRGLTPQQKKLAMKIKKARR---LLNKGKEPRIIRTHCRDFVITPDMVGLTFGVYNGKEFVEVKVTP-EMIGH YLGEFSLTRKPVQHG----APGMGATR----SSM-FVPIK-- >ARCH_Methanocella_sp_RC-I Concatenation of 2 sequences M----------GKR----------LMSQ------------------------------NRGKGSPTY-RATSSRFK---- ADLEHIK-T--FGDETIEGIITEVVHDPARNCPIIRVKFG-NGEERLILAPEGVGVGDKIACGI-S-AE-IKPGNTLPLS EIPEGCAICNIESQPGDGGAFARSSGVYAIIVAH--EGKKTVVQMPSGEIKRLNPKCRATIGVVAGGGRTEKPFVRAGNK -WYKMANKATKW-P-VVRGVAMNAVDHPFGGGGRQH----PGRPKTVSR----NTPPGRKVGS-IAARRTGGH------- MGHAHAPRRGSLGYSPRVRARSQKPKMRNWAEDQPKIQG-FVGFKAGMSHIVMVDDRPHSATEGMEISVPVTIVEAPQMH VAGIR----VYD----D--SPYGKKVIGEAW------ISDLKMTHL----------PKNGYKLVKKGVVADLRVMTVTLT SEVSGIPKKVPELMENRI---AGGDMAKRFEF-----AKSLMGK-AVGI--KDV-FAPGELVDVSAITKGYGTQGPVVRW GIAT-QKRKHARTGKKRH-VGNLGP--WNPH-RIRWQVPQLGQTGYHQRTEYNKRILKMGDKAE---------EITPAGG FLHYGLIRNDYIMLKGS-IPGPVKRMVRIR--MEVTILS-KSGKK--SAITVPA-VF----NE-EY-RPDIIKKAVLAAQ ANRLQPYGPDRTAGT--------LS-SAKKHSW----------GSGRGAAQVPRLA---NGSR--AAVVP----HA---- RGGRASHGPN-PLRIYTEKINDKERIKAIRSAVAATTNPELVKARGYKYEGAL---P-VVVDSEI---ESL--------- --KKTSLIV--IAEDN------GIKLAARNIPGVD-V---------------ATLDELNVEMLAPGTQAGRLTLWTEGAM KLLT-----------------------MSDNIMFTPRIEKVTVHMNVG----ESGKKLNNAEMIMEKITGQKPVRTVAKR TLPGFGIKKGESIGCKVTLRGDAADNFLKTALGIIENSIDA-------SRFDDNGNFAFGIEEHTDFPGME-----YDPE IGIYGMDVIVSVE-RPGYRIKRRKIQQQKIPSGHK-LTKDDSIAYVSKNYGVEVMAAEK-V--REIEVPQGVTVT-V--- -S-G--A-TLTTKGQKGQISREF-RFP-G--ISVRTDG-GK--VIV----E-T-GKDDKQTK-ATVGTYASHIKNMMTGV SEGYEYHMKIVYAHFPIQVKVEGKDK--VTIGNFLGERKARTANI-V-G-ETKVTVQ--G-D-KVVLTG-INKEDLGQTA ANIEQAC------RIRKR---DPR-VFQDGIYITSKA--MRAIKAKIPRSVHTATRLEVADNTGARLVEVISVLG-RKNR MPKAGIGDIFIGSVKKGTPE-----------MRKTIVRCVVIRQKKEYRRPSGLRVSFEDNACVLVD-DNND-PKGTEIK GPVAREV--AERYAKIGSTATIIVMS-K--Q---------KNKSYRGS-RTCGGGTHKNRRGGGSRGGRGHAGAC-K--- -HHTF-RAMKEGWM---FGK-HG--FTRINVGELSKIAEEKDG-GLAIDK---------LLG--NGR-V-T-R-K-YVI- TVGTASATAKAKIEELGGQIMK--FSGPAYTRREYMGGVPGVKVAQFDMG----NLTEELPIAVTLVVNETCQIRHDALE AARISANRYLLNDVG-KTNYRFKVRVYPHQVLRENKQATGAGADRVSDGMRRAFGKAVGTAARVYE-GQGVFTIWVNR-- ANFEKAKEAMRRAGHKLPTPYRV-VKVAFRRRREGKTDYHQRLKLIVSRKPRLVVRRTSSQVIAQILVT---RPEGDKVL AAATSA-ELAKTFGYK----GSG-KNTSAAYLTGLLIGYK--AQEAG-VEEAILDMGLRENRAGSRVYAALKGAVDSGLE VPCSEDVFPSDDRIRGEHIAGNTAS-----------KYTQYEKNGLKAADLPAHFDEVKGKIATT-AKAMAYEINVSPKH CQEICRQIRGMKLSAAKTYLQDVIDKKRSVPFKQHARNVGHKRHQS---GWPSGRYPVKASTEILKLLKHAEAN----A- EYK--GLETENMRIIHSTSKKGRVIQGIMPRAMGRATAWNIELVTVEVVIGETARVIVGDTVKVMRGD------AA-GTE GKVREIDVKRE--KVV--VEGVSVARADGK-------------------EEARPIHPSNLM-ITKLVL-------DD--P --KRVASL----------------ERK-----------------MA-------------IE-K--------------K-- ---FVQEGFKKAMVDEYF--LEKLE-----RAGYGGMEINRTP-M-GTQITLKAEKPGMIIGKAGKSIRRYTKEMDMRPQ IDVQEVKK---PELNAQMMATRLANALERGWYFRKAGQSTLQRIMDS-GAMGCEVIIAGKLTGA-RKRREKFIAGYIKHC GKPVEELVDVGYARAKKKLGIIGVKVRIMMVLMDPLANALSVIKNAETTGKTDCVIDPASKIIGNVLKVMQDQGYVGEFE FVD----N---G----KAGQLKVKLIGK---INK-------C---GVVKPRFAVGKTEM---EKWEKRYLPARNFGTLIL TTSKGVMSHYDAAKMGIGGEILAYVYMANQKARIRLSGTSPTKLDDVCGQVKKIAEKTGVSISGPVPLPTRRLVVPSRKS PSGEGSATWEHWEMRVHKRLIDI-DADERALRQLMRIQVPKDINIEIVLGQIFEGTVVSAKMSKSVVVSREYLKRDLKYD RYEKRRSKLHAHNPPC-INAKEGDKVVIAECRPLSKTKTFVVVEVAGHEPKRKEEFTYRGLTIAEMKKLDMNQVAALLPA RQRRKI-KREFGEEHQKLLNAVKAGET------------KIKTHLRDMIILPEMVGVTFEIHNGKEWKAVETTP-EMVGH YLGEFALTRHSVSHG----SAGIGATR----GSK-YVPLK-- >ARCH_Methanococcoides_burtonii_DSM_6242 Concatenation of 2 sequences MAKRI-------------------ISQN-------------------------------RGRGSPTY-RAPSHKYKAELK HPRVDEE-------STLNGTVIGIEHDPARSAPIAMVAFE-NGKKQFIVVPEGISVGEKLSCGV-S-AE-VKPGNTLPLA EIPEGIPICNIESKPNDGGQYARSSGVYATLVSR--ELSKVVVRMPSGVLKWFHPKCRATIGIVAGGGRVDRPFLKAGKK -YHKMKARAAKY-P-RVSGIAMNVVDHPFGGGNRKH----PGKPTTVSR----NAPPGRKVGH-IAARRTG-------KR MAKGHRPRRGSLAYSPRKRSQSHIPRFRSWPEKLQ---G-FAGYKVGMTHVIMIDDVKHSLTEGTEISVPVTIIETPAIR VAAIR----AYG----K--DTYGEIAIAEAW-------TDVLDSRRLKTAKNPDVNASLEKLLVESGRANDIRLITYTLP STLTGVPKKVPDVMETGV---SGSDVKAKFEY-----AKTVLGT-MVEI-SD-V-FDNGKIVDVAAITTGHGTQGPVKRW GINL-MKNKHSRQGSLRQ-VGTLGP--WTPA-HVSWRVPQAGQMGYHQRTDYNKRILKMSSDVD---------EVNPAGG FVNYGLVRGNYILIKGS-VPGPSKRLIRLR-MTTANIID-LSGNSK-GEIALPE-VF----S--EIFRPDLIKKAVLSAQ ANRLQPYGTKLYAGM-----------QTSAHSW----------GSGRGVAQVPRIS---NGSRV-AR-IP----QA---- VGGRRAHPPK-TETDRTEKINKKEKRLAVRSAIAATIDADLVKARGHKFTAEV---P-FVADDAI---EGL--------- --VKIKLIV--TGEES------LLSKAANNLPGVD-V---------------ATVTALNAELLAPGTHAGRLTVWTQSAI TNME------------------------MSNPMRNPKVEKVVVHMGVG----ESGQHLVDAEGILETITGQTVVRSYAKR TLPAFTIKKGEPIGCKVTLRGEAAEGFLETSLGIVEKRLNE-------SQFDIFGNVSFGVEEHTDYPGMR-----YDPN IGIFGMDITVVVN-RPGYRVSKRRIAKRKIPTSHK-ITKEDTISFFKDKYAVEVMAKEI-K--KIISIPEGVTVT-F--- -E-K--N-VLSASGPKGTNTRFL-WYP-G--VNIEVNG-SE--IIV----D-S-ASSRKKQK-AMVGTYTSHITNMMKGV VDGFEYHMKVVYSHFPMQIKVNG-KK--FVINNFLGEKKPRVSNI-L-G-ETSVKAS--G-D-EVIVSG-INKEDVGQTA ANIEQKT------KIKRF---DPR-VFQDGIYIVDKRV-MRGIRSKIPRALNAGAKIECVDNTGARTVEIISVKG-VKNR MPKGGIGDMCVVSVKKGTPE-----------MRKQILYAVIVRQKKEFRRPDGIRVAFEDNAVVIVD-DKGI-PKGTDIK GPVAREA--AERFPKIGTTASMIV---------MTSRKC-NTKKFRGS-RTCGGGTTKNRRGAGNRGGRGRSGEN----- -KHHF---TRALQLYIRGSE-RG--FSRVNVGELDGFAKLEAG-AYVMEK---------VLG--TGK-V-T-K-N-MVV- TACNFSEVARGKIETAGGSCMN--VKSRSFTRRKYMGGVPGSQVIHFDMG----NKTADFPVKITLLADERCQIRHTALE AARITANRAMTTAAG-RSGFHMKLRVYPHEVLRENKQATGAGADRVSSGMRAAYGKNVSTAARVSA-RQKIFTISVNK-- EHFIIAKDALRRAGQKLPTPVTI-VKVAFRRRREGRTDYHQRLRLLLSREDRVVVRKSARHMQIQLVAP---DANGDVTL SSAISK-ELAK-YGYE----GST-GNTTAAYLTGLLFGYK--TLAEG-YESGVLDIGIQASSAGSRVYAALKGVVDSGLD VPHNSSVFPSDERIRGEHVAEYM-----------------------EGSNLPEVFDAVKEKIETS-AKAMGSELHISPKK SRELCKAIKGMRTNAARQYLEDVVILKQAVPFGRHNDSLGHRKGPM-----AAGRYPVKVASEMLKLLKNAESN----A- EYK--GLNPEHMFIAHTAMNRGRVIHGMRPRARGRASPENTETVNLEMIISESANVIVGDTVIVMRGD------HA-GTK GKVEALSLKSG--TIV--VEGVSVSKVDGT-------------------EVPRPIYPSNVM-ITSLEM-------ND--K --HRDSILS---------------RGR-----------------MA-------------VE-K--------------K-- ---FVQDGYVKASMDEYF--AKQLS-----RAGYGGMDINRTP-M-GTQITVYAEKPGMVIGKAGKVIRKLTRDVDRLPQ IDAQEVKR---PELNAQMMASRLASSIERGWYFRKAGHNTMRAVMNA-GALGCEIVISGKLTGS-RSRVEKMVNGYIKHA GKPVDDIVDDGFATAVKKLGTLGCKVRIIMVLLDPLADALSIIKNAEAVGKDSCTIRPASKLIGNVLKVMNDRGYIGDFE FVE----D---G----KAGVYTVELIGR---INK-------C---GAIKPRYSV---GVTEFERWEKQFLPAKNFGVLIL TTPKGVISQYEARENNVGGQLLSFVY-MAQKARIRLSGTSPVNLDGVCDQVKAIANRTGVSISGPVPLPTKKLVVPVRKS PSGDGTATWDHWEMRVHKRLIDI-AADERALRQLMRIQVPKDISIEIVLGQIHVGTVVSAKMDRTVVIQQRREKLINKYQ RYEKRQSKIHAHNPPC-IDAKVGDIVTIAECRPLSKTKSYVVVKAEVKAPKRKGEYTFRGKTVAQLQEMSFEDFAELLPA KERRSI-RRGFSDSQKGVLQQFRDGKE------------SVRTHFRNMIIFPEMIGKNLEVYNGKEFVKIEIMP-EMIGH RFGEYSPTRNRVSHG----SAGVGATR----SSK-FVPLK-- >ARCH_Methanococcus_aeolicus_Nankai-3 Concatenation of 2 sequences M----------GKR----------LQSQ------------------------------NRGKGTPRY-TSPTHKRKGAVK YRKFDES----ERKDKIIGTIIDILHDPGRSSPIARVRYD-NGEERLILIPEGMKIKDTIECGI-S-AE-IKPGNVLPLG EVPEGIPVYNIETIPGDGGKLVRSGGCYAHVITH--DVSKTIIKLPSGHMKTLNPMCRATIGVVAGGGRKEKPITKAGKK -YHAMKAKAVLW-P-RVRGVAMNAVDHPFGGGNTQH----AGKPTTISR---HTSP-GRKVGH-IAARRTG-------KR GMKRNRPRRGSLAFSPRKRAKRPVPKIRSWPEETVKLLA-FPVYKAGTTHALYKENNPKSPNADQDVFTPVTVMEAPDIT IAGIR----AYG----KDTKGL--KALTEVW-------ADSFDINL----------PKEPKALDEVADKIVEVRAIVHTN PKDTNLPKKKPEIIEIKI------GGKNISDIIAYAKDI---GK-KLSI--NDV-FTGGEFIDTVAITKGKGFQGPVKRW GIKI-QFGKHQNKGVGRH-TGSIGP--WTPK-RIMWTVPMAGQVGFHQRTEYNKRILKIGENGS---------EIVPKGG FLNYGVVKNNYVLVKGS-VQGPAKRMVVLR--MKVKVYN-MDGSEK-GETELSA-VF----ET-EY-RPDLIKRAFLSSF TARLQPKGVDLMAGK-----------RTSAKSI----------GKGHGRARVQRTG---QGA---GAFVP----QA---- VGGRRCHPPK-VEKILHERVNKKERLKALASAIAASANIEMVKNRGHVVETVPSV-P-LIVSDDF---ESL--------- --KKTKLVV--VSGA---C---DAVKASKNLPGVD-V---------------ISANDLGVMHIAPGADSGRLTLWTESAV EEINMNFQEAW-----------------EKQPMSKPRIEKVTVNMGVG----ESGDKLLTAEKVVSEITGQKPVRTLAKQ TNPAFNIRKKLPIGLKITLRGKKAEEFLKDAFTAFTASGKQLFT----YSFDKRGNFSFGIPEHIDFPNQK-----YDPS VGIYGMDICVTFE-KPGYSVKRRKAKRANIPAKHL-VSKEEAINYIETIYGIKVVAAII-R--EEIEIPESVTIEVI--- -N-N--E-EVVVKAGGKELRRIL-SYP-D--VVIKKED-NK--VVV----E-S-LYPRKKQA-AIIGTFASHIKNIITGV SEGFEYKMKIRYAHFPMKISVKG-NE--VIIDNFLGEKHPRKATI-M-E-GVKVKVS--G-E-DVIVTG-IDKEKTGQTA ANIEQAT------RVRGR---DTR-VFQDGIYIVEKAGKMKGFGSKVIRSLPNGARLICADNTGAKELEIIAVKG-VARR LPAGGVGSLVFVSVKKGTPE-----------MRKQVLPAIIIRQKKEYRRPDGSRVKFEDNAAVIVT-PEGS-PKGSEIK GPVAKEA--AERWAGVSRLAKIIH-------MIRKSK---KITKLRGS-RTCGYGAAKKHRGAGHKGGKGLAGVTKH--- --RWI-HTVKYMPD--HIGK-YG--FKRINLGQLKESFEIVDG-KIVIEK---------VLG--KGK-I-T-C-P-MII- KAVEFSESAKEKIESAGGEFME--INKPAYTRKKYIRAVPQPKVVHYVNG----NKGGDFPVEVHLVVKDDIQIRHNALE SARIVGNKYTQNKCG-RLGYKFQIRVYPHQVLRENKMASGAGADRISDGMRLSFGKAVGTAARVRK-GQKIITISTTP-- ENVIHAKEALRRCNMKMPVKCKI-VRVPFRRRREGKTNFRLRLKLLLSRTPRLVARKSLNNIVAQIVEY---DEVGDKIV VSAHSK-EIVK-LGYK----GHC-GNVPAAYLTGLLLGKK--ALKEG-NEEAILDLGLNSATKGAAVLAILKGAVDAGMD IPHSEEILPGEDRINGSHVKEYAELLKVEDEEKYNKQFSKYLKNGLNPEDLPEHFEEIKEKINKT-ARAMGRSLRISRKH TIEICREISGMKLDKAIAYLNRVIELKQVVPFKRHGKDVPHKKGKY---GWTAGRFPQKASTQILSVLENAKKN----A- EYK--GMNTEKLRIKHISSNKGFTIKRHMPRAFGRASPKNQETVHVQVILEEALPVKTGDTVKILRGT------FK-GIE GEVSKVDYKSY--KIY--VEGAVNRKQDGN-------------------ESLYPIHPSNVM-IVKMDD-----------S --DDRRFKF---------------SNK-----------------M--------------IE-R--------------T-- ---FIKENVMETLVDEYL--KNKLP-----RAGYSHMDVKKTP-I-GTRITVFAEKPGFVIGRKGKMVKELTETIATKPQ IEVKQIES---PDLDAGVVAQKIASSLERGMHFRRVAHSAIRRVMAQ-GAKGVVVIVSGKLTG-ERSRTEKYMEGYMKHC GEPSEELVDQCHKIAKLKLGVVGVTVKIMMSLMDPLANALNHLSNCERVGKDVAYVQPASKLIGRVFKVMQDKGYMGNFE YIE----D---G----KAGIYKVELTGH---INK-------C---GAVRPRYAVKKTE---FEKFEKRYLPAKGFGLLIV STPKGLMTHDEAKSNGLGGRLISYIY--MQKARIKLSSTSYQELDGVCNNIKTIAEKTGVDMAGPIPLPTKTLKVTTRKS TDGEGSSSFDRWTMRVHKRVIDI-EADERTMKHIMKIRIPEAVQIEIELGQVFEGIVVSDKGHNAIVIKRDVVRYIPKYE RYEKRTTTMVAHCPSC-IDAKIGDKVKIAECRPISKTKSFVVIEKIELSPRRRVEFKYKGFTLGELQEMPIKKFMEIVPA RQRRSM-KKGITPKQRKLVMKIKKARR---LANRGKDPRTIRTHCRDFVITPEMIGLPFGIYNGKEFIEVKLVE-EAIGR FLGEFAPSRKVVQHG----SPGMGATR----GSM-FVPIK-- >ARCH_Methanococcus_maripaludis_C5 Concatenation of 2 sequences M----------GKR----------LISQ------------------------------NRGRGTPKY-RSPTHKRKGAVK YRSYDEM----EKDGKILGTVVDILHDPGRSAPVAKVRFA-NDEERLVLIPEGIQVGEEIECGI-S-AE-IKPGNVLPLG EIPEGIPVYNIETIPGDGGKLVRSGGCYAHVISH--DVGKTIVKLPSGFSKVLNPACRATVGVVAGGGRKEKPFVKAGKK -YHSLSAKAVAW-P-KVRGVAMNAVDHPYGGGRHQH----LGKPSSVSR---HTSP-GRKVGH-IASRRTG--------R GMKKNRPRRGSLAFSPRKRAKKLVPKIRSWPAKKVGLQA-FPVYKAGTTHALLIENNPKSPNNGQEVFTPVTVLETPDVT VAGIR----LYE----KTTKGL--KALTEVW--AEQLDGDLGRAKK----------EEKKTALDAVVEKATEVRAIVHTN PKTTGIPKKKPEVVEIRI-----GGSSVAERLAYAKEIL---GK-TLAI-GD-V-FEAGEIIDTLAITKGKGFQGSVKRW GIKV-QFGKHQRKGVGRH-TGSIGP--WRPR-RVMWTVPLPGQMGFHQRTEYNKRILKLGSEGA---------EITPKGG FLNYGAVKNGYVVVKGT-VQGPAKRLVVLR--MNVKVYN-LDGSEK-GDIELPA-VF----ET-EY-RPDLIKRAVISSL TAKLQPKGCDAFAGY-----------RTSAKSI----------GKGHGKARVRRTA---QGA---GAFVP----QA---- VGGRRAHPPK-VEKILFERINKKEKLKALASAIAASAIPEIVSARGHKIEGVPSL-P-LVVNAEF---EGL--------- --VKTKLVV--VGDA---C---EAIAASRNLAGVD-V---------------ITANDLSAIHIAPGTMAGRLTLWTENAI EKINMSFQEVW-----------------EKEPMKKPRIQKITVNFGVG----EAGDRLTIGAKVIEELTGQSPVRTLAKQ TNPAYGIRKKLPIGLKVTLRGKNAEEFLKNAFTAFKACGKVLYA----SSFDQVGNFSFGVPEHIDFPGQK-----YDPS VGIYGMDVCVTFD-KAGYRVKSRKLKRSHIPKKHL-VTKDEAIEYIQTKFDTEVVAALI-R--EEIEIPENVNVE-I--- -N-G--N-TVAVKSGAKELRRDL-MYP-G--IEISTED-GK--VVI----E-C-TFPRKVQT-AIVGTYRSHIQNMITGV TDGFEYKLVIRYAHFPMKVSAKG-NT--VTIDNFLGEKYTRTAKI-M-D-GVTVKVS--G-E-EVIVSG-ANKEFVGQTA ANIEQAT------KVKGR---DTR-IFQDGIYIVEKAGKMKGLGSTIVRSLPNGARLVCADNTGAKELEVIAVKG-TVRR LPAGGVGHMVFVSVKKGTPE-----------MRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVT-PEGT-PKGSEIK GPVSKEA--AERWPGVSRLAKIIH-------MIRKSK---KITKMRGS-RTCGYGEAKKHRGAGHRGGRGNAGHQ-K--- -HKWL-SVCKFNPD--YFGK-YG--FNRINIGELEDGKVVVDA-TTI-EK---------VLG--KGR-I-S-T-A-MVV- KAVEFSEGAKEKIEAAGGEFMT--TERRSYTRKEYVRAVPQPKVVHYVMG----NSSVEFPVEVQLVSKSDILIRHNALE SSRIAGNKYIMGECG-RTGYLFNIRVYPHEILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVKK-GQEIITIGVNP-- ERFYAAKEALRRCSMKLPTACKIVVRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNVTAQLMSY---DEKGDVVL VSAHTK-ELVK-MGYK----GHC-GNLPAAYLTGLLLGKK--AVKEG-AEEAILDKGLHRATKGAAIFAVLKGALDAGMD IPHGDEIIAEEERLNGTHVKNYAESLKE-DADAYKKQFSKYLEKGLNPEDLPEHVAELKEKIKNT-ARAMGRTLRISRKH AIELCRELSGMKLDAAVAYLNRVIALETPVPFKVHNKDLPHRKGKI---GTHSGRFPQKASLEILQVLDNAKKN----A- EQK--GLNTEKLRIKHISSNRGFTIKRYMPRAFGRASPKNQETIHIQVILEESLPVKKGDTVKVLRGN------FK-GIE GEVSKVDYAGY--KII--VEGVVNKKQDGT-------------------ETAYPIHPSNVM-ITKLDE------------ ------------SD----------EKR---FKNSSN--------M--------------IE-R--------------T-- ---FVGENVSETLIDEYF--KTKLV-----RAGYSHIDLKKTP-I-GTRITVFAEKPGFVIGRKGKMVKELTETLAKEPQ IEVKQVEN---PDLDPAIVGHKIASSLERGMHFRRTAHSAIRRVMGS-GAKGVSIIVSGKLSG-ERSRTEKFMDGYMKHC GEPAEALVNKSHQLAKLKLGVVGVTVKIMMSLMDPLANALNHVSNCESVGKNVAYLKPASKLIGRVLNVMQDQGYIGNFE YIE----D---G----KAGVYKVDLIGQ---INK-------C---GAVKPRYAVKNHD---FEKFEKRYLPAKGFGLLIV STPKGLMTHDEARNAGVGGRLISYIY--MQKARIKLSSTQHTELDGVCNQIKAIAEKTGVDMAGPIPLPTKALKVTTRKS TDGEGSSSFDRWTMRVHKRVIDI-EADERTMKHIMKVRIPDTVQIEIELGQIFEGTVTSDKGHDTIVLKREVTGYISKYE RYEKRTTSLVAHNPAC-IKAKVGDTVKVMECRPISKTKSFVVIEKTENLPRRRVEFKYKGFTLEELQEMPIKKFMEIVPS RQRRTM-ARGITPKQRKLVMKIKKARR---LTNRGKEARVIRTHCRDFVITPEMIGLTFGIYNGKEFKEIKLVE-ETVGR FLGEMAPTRAVVQHG----SPGMGATR----GSM-FVPIK-- >ARCH_Methanococcus_maripaludis_C6 Concatenation of 2 sequences M----------GKR----------LISQ------------------------------NRGRGTPKY-RSPSHKRKGAVK YRSYDEM----EKDGKILGTVVDILHDPGRSAPVAKVRFA-NDEERLVLIPEGIQVGEEIECGI-S-AE-IKPGNVLPLG EIPEGIPVYNIETIPGDGGKLVRSGGCYAHVVSH--DVGKTIVKLPSGFSKVLNPACRATVGVVAGGGRKEKPFVKAGKK -HHSLSAKAIAW-P-KVRGVAMNAVDHPYGGGRHQH----LGKPSSVSR---HTSP-GRKVGH-IASRRTG--------R GMKKSRPRRGSLAFSPRKRAKKLVPKIRSWPAKKVGLQA-FPVYKAGTTHALLIENNPKSPNNGQEVFTPVTVLETPDVT VAGIR----LYE----KTTKGL--QALTEVW--AEQLDGDLGRVKK----------EEKKTALDAVLEKATEVRAIVHTN PKTTGIPKKKPEVVEIRI-----GGSSVAERLAYAKEIL---GK-TLAI-SD-V-FEAGEIIDTLAITKGKGFQGSVKRW GIKV-QFGKHQRKGVGRH-TGSIGP--WRPR-RVMWTVPLPGQMGFHQRTEYNKRILKLGSEGA---------EITPKGG FLNYGAVKNGYVVVKGT-VQGPAKRLVVLR--MNVKVYN-LDGSEK-GDIELPA-VF----ET-EY-RPDLIKRAVISSL TAKLQPKGCDAFAGY-----------RTSAKSI----------GKGHGKARVRRTA---QGA---GAFVP----QA---- VGGRRAHPPK-VEKILFERINRKERLKALASAIAASANPEIVSARGHKIEGVPSL-P-LVVNAEF---ESL--------- --AKTKLVV--VGDA---C---DAVAASRNLAGVD-V---------------ITANDLSAIHIAPGTMAGRLTLWTESAI EKLNMSFQEVW-----------------EKEPMKKPRIQKVTVNFGVG----EAGDRLTIGAKVIEELTGQSPVRTLAKQ TNPAFGIRKKLPIGLKVTLRGKNAEEFLGNAFTAFKTSGKVLYA----SSFDQVGNFSFGVPEHIDFPGQK-----YDPS IGIYGMDVCVTFE-KSGYRVKSRKVKRSHIPKKHL-VTKDEAIEYIQTKFDTEVVAALI-R--EEIEIPANVNVE-I--- -N-G--N-TVAVKSGAKELKRDL-LYP-G--IEISTED-GK--VVI----E-C-TFPRKAQT-AIVGTYRSHIQNMIKGV TDGFEYKLVIRYAHFPMKVSAKG-NT--VMIDNFLGEKYTRTAKI-M-D-GVTVKVS--G-E-EVIVSG-ANKEFVGQTA ANIEQAT------KVKGR---DTR-IFQDGIYIVEKAGKMKGLGSTIVRSLPNGARLVCADNTGAKELEVIAVKG-TVRR LPAGGVGHMVFVSVKKGTPE-----------MRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVT-PEGT-PKGSEIK GPVSKEA--AERWPGVSRLAKIIH-------MIRKSK---KITKMRGS-RTCGYGEAKKHRGAGHRGGRGNAGHQ-K--- -HKWL-SVCKFNPD--YFGK-YG--FNRINIGELEDGKVVVDA-TEI-EK---------VLG--KGR-I-S-T-A-MVV- KAVEFSEGAKEKIEAAGGEFMT--TERRSYTRKEYVRAVPQPKVVHYVMG----NSSVEFPVEVQLISKSDILIRHNALE SSRIAGNKYILRECG-RTGYLFNIRVYPHEILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVKK-GQEIITIGVNP-- EKFYAAKEALRRCSMKLPTACKIVVRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNVIAQLMAY---DEKGDVVL VSAHSR-ELVK-MGYK----GHC-GNLPAAYLTGLLLGKK--AVKEG-AEEAILDKGLHRATKGAAIFAVLKGALDAGMD IPHGDEIIADEERLNGTHVKNYAESLKE-DADAYKKQFSKYLEKGLNPEDLPEHVEELKEKIKNT-ARAMGRTLRISRKH AIELCRELSGMKLDAAVAYLNRVIALETPVPFKVHNKDLPHRKGKI---GTHSGRFPQKASLEILQVLDNAKKN----A- EQK--GLNTEKLRIKHISSNRGFTIKRYMPRAFGRASPKNQETIHIQVILEESLPVKKGDTVKVLRGN------FK-GIE GEVSKVDYAGY--KII--VEGVVNKKQDGT-------------------ETAYPIHPSNVM-ITKMDE-------SD--- ------------------------EKR---FKNSSN--------M--------------IE-R--------------T-- ---FVGENVSETLIDEYF--KTKLV-----RAGYSHIDLKKTP-I-GTRITVFAEKPGFVIGRKGKMVKELTETLSTEPQ IEVKQVES---PDLDPAIVGHKIASSLERGMHFRKTAHSAIRRVMGS-GAKGVAIIVSGKLSG-ERSRTEKFMDGYMKHC GEPAEALVNKSHQLAKLKLGVVGVTVKIMMSLMDPLANALNHVSNCESVGKNVAYLKPASKLIGRVLNVMQDQGYIGNFE YIE----D---G----KAGVYKVDLIGQ---INK-------C---GAVKPRFAVKNHD---FEKFEKRYLPAKGFGLLIV STPKGLMTHDEARSAGVGGRLISYIY--MQKARIKLSSTQHVELDGVCDQIKAIAEKTGVDMAGPIPLPTKALKVTTRKS TDGEGSSSFDRWTMRVHKRVIDI-EADERTMKHIMKVRIPDTVQIEIELGQIFEGTVTSDKGHDTIVLKREVTGYISKYE RYEKRTTSLVAHNPAC-IKAKVGDTVKVMECRPISKTKSFVVIEKTENLPRRRVEFRYKGFTLEELQEMPIKKFMEIVPS RQRRTM-LRGITPNQRKLVMKIKKARR---LTNRGKEPRVIRTHCRDFVITPEMIGLTFGIYNGKEFKDVTLVE-ETVGR FLGEMAPTRAVVQHG----SPGMGATR----GSM-FVPIK-- >ARCH_Methanococcus_maripaludis_C7 Concatenation of 2 sequences M----------GKR----------LISQ------------------------------NRGRGTPKY-RSPTHKRKGAVK YRSYDEM----EKDGKILGTVVDILHDPGRSAPVAKVRFA-NDEERLVLIPEGIQVGEEIECGI-S-AE-IKPGNVLPLG EIPEGIPVYNIETIPGDGGKLVRSGGCYAHVVSH--DVGKTIVKLPSGFSKVLNPACRATVGVVAGGGRKEKPFVKAGKK -HHSLSAKAIAW-P-KVRGVAMNAVDHPYGGGRHQH----LGKPSSVSR---HTSP-GRKVGH-IASRRTG--------R GMKKSRPRRGSLAFSPRKRAKKLVPKIRSWPAKKVGLQA-FPVYKAGTTHALLIENNPKSPNNGQEVFTPVTVLETPDVT VAGIR----LYE----KTTKGL--KALTEVW--AEQLDNDLGRVKK----------EEKKTALDAVLEKATEVRVIVHTN PKTTGIPKKKPEVVEIRI-----GGSSVAERLAYAKEIL---GK-TLAI-SD-V-FEAGEIIDTLAITKGKGFQGSVKRW GIKV-QFGKHQRKGVGRH-TGSIGP--WRPR-RVMWTVPLPGQMGFHQRTEYNKRILKLGSEGA---------EITPKGG FLNYGAVKNGYVVVKGT-VQGPAKRLVVLR--MNVKVYN-LDGSEK-GDIELPA-VF----ET-EY-RPDLIKRAVISSL TAKLQPKGCDAFAGY-----------RTSAKSI----------GKGHGKARVRRTA---QGA---GAFVP----QA---- VGGRRAHPPK-VEKILFERINRKEKLKALASAIAASAIPEIVSARGHKIEGVPSL-P-LVVNADF---ESL--------- --AKTKLVV--VGDA---C---EAIAASRNLAGVD-V---------------ITANDLSAIHIAPGTMAGRLTLWTENAI EKINMSFQEVW-----------------EKEPMKKPRIQKVTVNFGVG----EAGDRLTIGAKVIEELTGQSPVRTLAKQ TNPAFGIRKKLPIGLKVTLRGKNAEEFLGNAFSAFKTCGKVLYA----SSFDQVGNFSFGVPEHIDFPGQK-----YDPS IGIYGMDICVTFE-KSGYRVKSRKVKRSHIPKKHL-VTKDEAIEYIQAKFDTEVVAALI-R--EEIEIPENVNVE-V--- -N-G--S-TVAVKSGAKELKRDL-LYP-G--IEISTED-GK--VVI----E-C-TFPRKAQT-AIVGTYRSHIQNMITGV TDGFEYKLVIRYAHFPMKVSAKG-NT--VTIDNFLGEKYTRTAKI-M-D-GVTVKVS--G-E-EVIVSG-ANKEFVGQTA ANIEQAT------KVKGR---DTR-IFQDGIYIVEKAGKKGLGSTIVR-SLPNGARLVCADNTGAKELEIIAVKG-TVRR LPAGGVGHMVFVSVKKGTPE-----------MRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVT-PEGT-PKGSEIK GPVSKEA--AERWPGVSRLAKIIH-------MIRKSK---KITKMRGS-RTCGYGEAKKHRGAGHRGGRGNAGHQ-K--- -HKWL-SVCKFNPD--YFGK-YG--FNRINIGELEDGKVVVDA-TEI-EK---------VLG--KGR-I-S-T-A-MVV- KAVEFSEGAKEKIEAAGGEFMT--TERRSYTRKEYVRAVPQPKVVHYVMG----NSSVEFPVEVQLISKSDILIRHNALE SSRIAGNKYILRECG-RTGYLFNIRVYPHEILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVKK-GQEIITIGVNP-- EKFYAAKEALRRCSMKLPTACKI-VRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNVIAQLMAY---DEKGDVVL VSAHSR-ELVK-MGYK----GHC-GNLPAAYLTGLLLGKK--AVKEG-AEEAILDKGLHRATKGAAIFAVLKGALDAGMD IPHGDEIIADEERLNGTHVKNYAESLKE-DADAYKKQFSKYLEKGLNPEDLPEHVEELKEKIKNT-ARAMGRTLRISRKH AIELCRELSGMKLDAAVAYLNRVIALETPVPFKVHNKDLPHRKGKI---GTHSGRFPQKASLEILQVLDNAKKN----A- EQK--GLNTEKLRIKHISSNRGFTIKRYMPRAFGRASPKNQETIHIQVILEESLPVKKGDTVKVLRGN------FK-GIE GEVSKVDYAGY--KII--VEGVVNKKQDGT-------------------ETAYPIHPSNVM-ITKLDE-------SD--- ------------------------EKR---FKNSSN--------M--------------IE-R--------------T-- ---FVGENVSETLIDEYF--KTKLV-----RAGYSHIDLKKTP-I-GTRITVFAEKPGFVIGRKGKMVKELTETLSTEPQ IEVKQVES---PDLDPAIVGHKIASSLERGMHFRKTAHSAIRRVMGS-GAKGVSIIVSGKLSG-ERSRTEKFMDGYMKHC GEPAEALVNKSHQLAKLKLGVVGVTVKIMMSLMDPLANALNHVSNCESVGKNVAYLKPASKLIGRVLNVMQDQGYIGNFE YIE----D---G----KAGVYKVDLIGQ---INK-------C---GAVKPRFAVKNHD---FEKFEKRYLPAKGFGLLIV STPKGLMTHDEARNAGVGGRLISYIY--MQKARIKLSSTQHTELDGVCDQIKAIAEKTGVDMAGPIPLPTKALKVTTRKS TDGEGSSSFDRWTMRVHKRVIDI-EADERTMKHIMKVRIPDTVQIEIELGQIFEGTVTSDKGHDTIVLKREVTGYISKYE RYEKRTTSLVAHNPAC-IKAKVGDTVKVMECRPISKTKSFVVIEKTENLPRRRVEFKYKGFTLEELQEMPIKKFMEIVPS RQRRTM-LRGITPNQRKLVMKIKKARR---LTNRGKEPRVIRTHCRDFVITPEMIGLTFGIYNGKEFKEIKLVE-ETVGR FLGEMAPTRSVVQHG----SPGMGATR----GSM-FVPIK-- >ARCH_Methanococcus_maripaludis_S2 Concatenation of 2 sequences YGDIM------GKR----------LISQ------------------------------NRGRGTPKY-RSPTHKRKGAVK YRSYDEM----EKDGKILGTVIDILHDPGRSAPVAKVKFA-NDEERLVLIPEGIQVGEEIECGI-S-AE-IKPGNVLPLG EIPEGIPVYNIETIPGDGGKLVRSGGCYAHVISH--DVGKTIVRLPSGFSKVLNPACRATVGVVAGGGRKEKPFVKAGKK -YHSLSAKAVAW-P-KVRGVAMNAVDHPYGGGRHQH----IGKPSSVSR---HTSP-GRKVGH-IASRRTG-------KR GMKKNRPRRGSLAFSPRKRAKKLVPKIRSWPAKKVGLQA-FPVYKAGTTHALLIENNPKSPNSSQEVFTPVTVLETPDVT VAGIR----LYE----KTTKGL--KALTEVW--AEQLDSDLGRAKK----------EEKKTVLDAVLEKATEVRAIVHTN PKTTGIPKKKPEVVEIRI-----GGSSVAERLAYAKEIL---GK-TLAI-SD-V-FEAGEIIDTLAITKGKGFQGSVKRW GIKV-QFGKHQRKGVGRH-TGSIGP--WRPR-RVMWTVPLPGQMGFHQRTEYNKRILKLGSEGA---------EITPKGG FLNYGAVKNGYVVVKGT-VQGPAKRLVVLR-IMNVKVYN-LDGSEK-GDIELPA-VF----EA-EY-RPDLIKRAVISSL TAKLQPKGCDAFAGY-----------RTSAKSI----------GKGHGKARVRRTA---QGA---GAFVP----QA---- VGGRRAHPPK-VEKILFERINRKEKLKALASAIAASANPEIVSARGHKIEGVPSL-P-LVVNAEF---ESL--------- --VKTKLVV--VGDA---C---EAITASRNLAGVD-V---------------ITANDLSAIHIAPGTMAGRLTLWTENAI EKINFRCNAHKIRGG----RNMSFQEVWEKEPMKKPRIQKVTVNFGVG----EAGDRLTIGAKVIEELTGQSPVRTLAKQ TNPAFGIRKKLPIGLKVTLRGKKAEEFLKNAFTAFKACGKTLFA----SSFDQVGNFSFGVPEHIDFPGQK-----YDPS VGIYGMDICVTFE-KSGYRVKSRKVKRSHIPEKHL-VTKDEAIEYIQAKFDTEVVAALI-R--EEIEIPENVNVE-I--- -N-G--S-TVVVKSGAKELKREL-MYP-G--IEISTED-GK--VVI----E-C--AFPRKAQTAIVGTYRSHIQNMITGV TDGFEYKLVIRYAHFPMKVSAKG-NT--VMIDNFLGEKYTRTAKI-M-D-GVTVKVS--G-E-DVVVSG-ANKEFVGQTA ANIEQAT------KVKGR---DTR-IFQDGIYIVEKAGKMKGLGSNIVRSLPNGARLVCADNTGAKELEVIAVKG-TVRR LPAGGVGHMVFVSVKKGTPE-----------MRKQVLPAIIIRQKKEYRRADGTRVKFEDNAAVIVT-PEGT-PKGSEIK GPVSKEA--AERWPGVSRLAKIIH------GDLMIRKSK-KITKKRGS-RTCGYGEAKKHRGAGHRGGRGNAGHQ-K--- -HKWL-SVCKFNPD--YFGK-YG--FNRINIGELDAFQVEEGK-VVVNEK---------VLG--KGR-I-S-T-A-MVV- KAVEFSEGAKEKIEAAGGEFMT--IERRSYTRKEYVRAVPQPKVVHYVMG----NPSAEFPVQVQLVSKSDILIRHNALE SSRIAGNKYILSECG-RTGYLFNIRVYPHEILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVKK-GQEIITIGVNP-- EKFYAAKEALRRCSMKLPTACKIVVRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNVTAQLMAY---DEKGDVVL VSAHSK-ELVK-MGYK----GHC-GNLPAAYLTGLLLGAK--AVKED-VKEAVLDKGLHRATKGAAIFAVLKGALDAGMD IPHGDKIIADEERLNGTHVKNYAESLKE-DADAYKKQFSKYLEKGLNPEDLPEHVEELKEKIKNT-ARAMGRTLRISRKH AIELCRELSGMKLDAAVAYLNRVIALETPVPFKVHNKDLPHRKGKI---GTHSGRFPQKASLEILNVLDNAKKN----A- EQK--GLNTEKLRIKHISSNRGFTIKRYMPRAFGRASPKNQETIHIQVILEESLPVKKGDTVKVLRGN------FK-GIE GEVSKVDYAGY--KII--VEGVVNKKQDGN-------------------ETAYPIHPSNVM-ITKLDE------------ ------------SD----------EKR---FKNSSN--------SLKNSTNGETMIE-----R--------------T-- ---FVGENVSETLIDEYF--KTKLV-----RAGYSHIDFKKTP-I-GTRITVFAEKPGFVIGRKGKMVKELTETLATEPQ IEVKQVEN---PDLDPAVVGHKIASSLERGMHFRKTAHSAIRRVMGS-GAKGVAIIVSGKLSG-ERSRTEKFMDGYMKHC GEPAEALVNKSHQLAKLKLGIVGVTVKIMMSLMDPLANALNHVSNCESVGKNVAYLKPASKLIGRVLNVMQDQGYIGNFE YIE----D---G----KAGVYKVDLIGQ---INK-------C---GAVKPRYAVKNHD---FEKFEKRYLPAKGFGLLIV STPKGLMTHDEARNAGVGGRLISYIYHIMQKARIKLSSTQHTELDGVCDQIKAIAEKTGVDMSGPIPLPTKALKVTTRKS TDGEGSSSFDRWTMRVHKRVIDI-EADERTMKHIMKVRIPDTVQIEIELGQIFEGIVTSDKGHDTIVIKREVTGYISKYE RYEKRTTSLVAHNPAC-IKAKVGDTVKVMECRPISKTKSFVVIEKTENLPRRRVEFKYKGFSLEELQEMPIKKFMEIVPS RQRRTM-ARGITPKQRKLVMKIKKARR---LTNRGKDARVIRTHCRDFVITPEMIGLTFGIYNGKEFKEIKLVE-ETVGR FLGEMAPTRGVVQHG----SPGMGATR----GSM-FVPIK-- >ARCH_Methanococcus_vannielii_SB Concatenation of 2 sequences M----------GKR----------LISQ------------------------------NRGRGTPKY-RSPSHKRKGEVK YRSYDEM----EKVGKVLGTVIDVLHDPGRSAPVAKVRFA-NGEERLVLIPEGISVGEQIECGI-S-AE-IKPGNVLPLG EIPEGIPVYNIETIPGDGGKLVRAGGCYAHVVAH--DIGKTIVKLPSGYAKVLNPACRATIGVVAGGGRKEKPFVKAGKK -HHSLSAKAVAW-P-KVRGVAMNAVDHPYGGGRHQH----LGKPSSVSR----NTSPGRKVGH-IASRRTG--------R GMKKNRPRRGSLAFSPRKRAKKLVPKIRSWPAKKVGLQA-FPVYKAGTTHALLVENNPKSPNNGQEVFSPVTVLETPEIT VAGIR----AYG----KTTKGL--KALTEVW--AKQQDKELGRTKK----------EEIKTVLDAVLEKTVDLRVIVHTN PKTTGIPKKKPEVVEIRV-----GGSSVAEKLAYAKDIL---GK-TLSI--NDV-FETGEFIDTLAVTKGKGFQGPVKRW GVKI-QFGKHQRKGVGRQ-TGSIGP--WRPK-RVMWTVPLAGQMGFHQRTEYNKRILKLGSEGA---------EITPKGG FLNYGAVKNGYVVVKGT-VQGPAKRLVVLR--MNVKVYN-LDGSEK-GAIELPS-VF----ET-EY-RPDVIKRAVISSL TARLQPKGSDPLAGY-----------RTSAKSI----------GKGHGKARVRRTA---QGA---GAFVP----QA---- VGGRRAHPPK-VEKILFERINRKERLKALASAIAASANSEIVAARGHKIEGVPSL-P-LVVNAEF---ESL--------- --VKTKLVV--VGDA---C---DAVAASRNLAGVD-V---------------ITANDLSAIHIAPGTMAGRLTLWTENAI EKLKMSFQEVW-----------------EKEPMKKPRIQKVTVNFGVG----EAGDRLTIGAKVIETLTGQAPVRTLAKQ TNPAFGIRKKLPIGLKVTLRGKNAEEFLENAFVAFKVSGKVLYA----SSFDKVGNFSFGVPEHIDFPGQK-----YDPT VGIYGMDICVTFE-KPGYRVKSRKLKRSHIPAKHL-VKKEEAIEYIEKKFGAEVVAALI-R--EEIEIPGNVSVE-V--- -N-G--S-EVVVKSGAKVLKREL-AFP-G--IEIKMEN-EK--VVV----E-S-TFPKKNQT-AMVGTYRSHIQNMIKGV SEGFEYKLVIRYAHFPMKVTFKG-NT--VIIDNFLGEKYPRTAKV-M-E-GVTVKVN--G-E-EVIVSG-TNKEFVGQTA ANIEQAT------KVKGR---DTR-IFQDGIYIVEKAGKMKGLGSTIVRSLPNGARLVCADNTGAKELEVIAVKG-TVRR LPSAGVGQIVFVSVKKGTPE-----------MRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVT-PEGT-PKGSDIK GPVSKEA--AERWPGVSRLAKIIH-------MIRKSK---KITKQRGS-RTCGYGEAKKHRGAGHRGGRGNAGHQ-K--- -HKWL-SVCKFNPE--YFGK-YG--FNRINVGELKDAFKLKDG-KVVVEK---------ILG--KGR-I-S-T-A-MVV- KAVEFSEGAKEKIEAAGGEFMD--TTKRAYTRKEYVRAVPQPKVVHYVMG----NTSADFPVEFHLVSKVDILVRHNALE ASRIAGNKYILRECG-RLGYKFHIRVYPHQILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVAK-GQTIISISVNP-- DKYKEAKEALRRCSMKLPAACKVVVRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNIIAQLMAY---DEKGDIVL VSAHSR-ELVK-MGYK----GHC-GNLPAAYLTGLLLGKK--AVEEG-LEEAILDKGLHRATKGAAIFAVLKGALDAGMD IPCGEEIIADEERLNGTHIKQYAELLKE-DEEAYKKQFSKYLEKGLNPEDLPEHFEELKGKISKT-AKAMGRTLRISKKH ALEICREINGMKLETAVSFLNRVLALETPVPFKVHNKDVPHRKGKI---GTHAGRFPQKATEEILKVLDNAKKN----A- EYK--GLNTEKLRIKHISSNKGFIIKRFMPRAFGRASPKYQETIHIQVILEEALPVKKGDTVKVLRGS------FK-GIE GEVSKVNYSGY--KII--VEGVVNKKQDGK-------------------ETPYPIHPSNVM-ITKMED-------SD--- ------------------------EKR---FKTSNK--------M--------------IE-R--------------T-- ---FIAENVSETLIDEYF--KGKLV-----RAGYSHLELKKTP-I-GTRITVFAEKPGFVIGRKGKMVKELTDTLTEVPQ IEVKPLET---PDLDPAIVGHKIAASLEKGMHFRKTAHSAVRRVMAA-GAKGVAIIISGKLSG-ERSRTEKFMDGYMKHC GEPAEELVIKSHQLAKLKLGIVGVTVKIMMSLMDPLANALNHVSNCEGVGKNVAYLKPASKLIGRVLKVMQDQGYIGNFE YIE----D---G----KAGVYKVDLIGQ---INK-------C---GAVKPRYAVK---YQEFEKFEKRYLPAKGFGLLIV STPKGLMTHDEARTAGVGGRLISYVY--MQKARIKLSSTKHEELDSVCNQIKAIAEKTGVDMAGPIPLPTKSLKITTRKS TDGEGSSSFDRWTMRVHKRVIDI-EADERTMKHIMKVRIPDAVQIEIELGQIFEGVVSGDKGHNTIVIKREVTGYISKYE RYEKRTTSLVAHNPPC-INAKTGDVVKVMECRPVSKTKSFVVIEKTENLPRRRVEFKYKGFTLPELQEMPIKKFIEIVPA RQRRTM-SRGITPNQRKLVMKIKKARR---LVNRGKEPRVIRTHCRDFVITPEMIGLTISIYTGKQFKEIKLVE-ETLGR FLGEMAPTRGIVQHG----SPGMGATR----GSM-FVPIK-- >ARCH_Methanocorpusculum_labreanum_Z Concatenation of 2 sequences M----------GHR----------ISTQ------------------------------SRGKGGPTY-RAPSHQYK---- AELKHFG-S--AL-ETVRATVIDIEHDPARHTPIAVVKIEGKAKKEYALITEGVGIGQELVWGP-E-AT-VVNGNSLPLS AIPTGVAVCNIEARPGDGGKFVRSSGVQAVIIGK--SAGKVGVRMPSGKPKWFNEACLATVGLVAGGGRIDKPILKAGKQ -YHKMKTSATRW-P-RVRGVAMNVIDHPFGGGGHQH----PGKPKTVAR----GASPGRKVGS-VAARRTG-------YR -MRTVRPRAGSLAYYPRKRAKGIVPKYQSWPEGQPMLQG-FAGYKAGMTHVIMIDDHKKSPTEGKEVMVPVTVIEIPAMT VAAIR----VYV----K--DTYGKHPLTEVW------AEN---KTNNAAKATEKINAAIGDVE--------VMVLMYTKP TELTGVPKKVPDLMEIRV---AGGSAQERFDY-----ALSILGT-DVDM-KS-L-LSEGQFADITGITKGKGFQGAVKRF GITL-RKRKHARTKKERH-IGTLGP--WTPH-HVRWQVPMPGQMGFQQRTEFNKRIIKIGENAD---------EINPAGG FLHYGLVRNNYVLIKGS-IPGPAKRLVRIR--MKANVKA-INGSVL-HEIELPA-VF----D--EAYRPDLIKRAILAYQ SEQYQPHGADPYAGM-----------RTSAEGW--------GSKRGEAKIPRIK-----NGSRA-AK-VP----NV---- KGGHPAHAPK-AEKILVEKINKKEKAKAIRSAIAATVNTELVTARGHKFEGEA---A-IIVDDSF---EQI--------- --AKTALIV--T---S------GEFLAGANIAGVD-C---------------VSVNALNINVLAPGADAGRLTVWTEAAI KKFV-------------------------MTDMQTPFVAKVVVHMGVG----EAGERLVNAENIMADLTGAKPIRSYARN TLPAFGIRKGQPIGCKATLRGKKAMDFLEMAL-----KTYAVENVLHTRQFDATGNFGFGIEEHTDFPGQA-----YDPK IGIYGMDIIAVIE-KKGTRTARRKIQQKKINSKLH-VAREESMKFVTETFGIEV---MA-E--LIFEIPKGVTIT-K--- -T-G--D-LVTVKGSKGELTRTM-YHP-A--ITITIAD-GS--VTL----V-S-TSARRSVY-ALLGTYKAHLGVMSKGV SEGYEYHMKIVYNHFPIQVKVAG-DK--VEIGNFLGEKQARYANI-V-E-GVKVKVQ--G-D-ELILNG-INRETIGNTA ANVEQAC------KVRNR---DPR-VFQDGIYITSRGD-MKGLTSKIPRALQTGSKMVCADNTGARVVQIVSVFG-VKNR QPKMGLGDLATVTVKKGTPD-----------MKRKLVRAVVVRQKKEFRRPNGLRVSFEENAMILLN-ENGD-PRGTDIK GPVAREV--AERFPKVGSMATIIIMP-V--N---------KRSKFRGT-RTCGGGTHKNRRGAGNRGGRGAAGWRDHNF- -TRWY-LLGKTEGK-------HG--FVSLDIGDLVARGIATQN-GDVIEK---------ILG--GGK-V-T-H-K-LAI- TAENFSGRAVAKIEELGGTTMN--LAKKAYCRREYMGGVPGLKVVQFDMG--NLSEDFPVAIHLEAL--EACQIRHTAME AARINMNRRLMKTVG-RNNFHLKIRAYPHHVLREHKQATGAGADRVSEGMRLAFGKAVGTAARVAP-RQRVFTVWTTP-- QYVDQAKDALLHSGYKLPTPVRV-IFVQFRRRREGRTDYYQRQRLIVSGRNRMVVRKTNRHIIIQLIAA---QMDGDYTL VHVNSR-ELVN-FGYK----GYL-GNTPAAYLTGMLFAVR--AQKAG-YEGGIADIGLQVASTGARVFAAIKGAVDAGFD VPVGEAILPDDDRCNGAHIAEYD-E---------------------RFAGLVENVEATKDAIDNI-ARAKANELGCSPKH AVEIAHLVRNMMADDAVAYLEQVIDLKRAVPFHRFNRNVSHQKSLNGKTGTAAGRYPVKAAAEYVRLIRSAQKN----A- EYA--GLAPEKMVIIHAAANKGRCIKGIFPRAMGRATPKHKDSVNVEIILRESFRVVTGDTVKVLRGE------FK-GIE GVVDGVDVKNT--KVL--VHGVYVKKANGE-------------------DVPRPLDPSKIM-ITKLNT-------KD--- ------------------------AVR---VARLEV---KA---MT-------------IE-K--------------K-- ---FVADGVRKVRVEQYL--NKELK-----RAGYGGMDIVRTP-V-GTQVTIFAEKPGIVIGKGGKLVRQLTTDLSTVPQ VEVQQVAN---PNLNAQIMAERLANALERGWYFRKAGTSVIRRVMDS-GALGCEVIIAGKLTGA-RARVQKFVEGYIKHS GEPSESIVEKGYATAIKKLGIIGVQVKIVMTKQNPIADAMSAIKNAGDTGKLAVTVEPASRLFGDMLKVMQEYGYITGFE KID----D---G----RGGQFQIALSGG---INK-------C---GVITPRFSVKVEDL---ESWEIRYLPGKGFGIIIL TTSKGVMSHEQARKLGVGGELLGYVF--MQKARIRLTGTDYEKVETVCTRIREIAERTGVNMAGPIPLPTKRLIVPIRKS PDGEGTATWDRWQMRVHKRLIDL-DADERALRQLMRIQVPKDISIEIVLGQVITGKVVSERMQGTVVVERNFLHKVQKYD RYEKRSSKIHAHMAPC-LNAKIGDEVKIAECRPLNKTTSYVVVEVIKE-PKRREEYTYHGYNIEQLKAMSMDELLAIMPS GARRKV-LRGFTRDEEDVRAKIAEGDG-------------VRTHSRSMIILPEMVGKNVAIYSGKEFINVEIPV-EGVFH YFGEFALTRKKVTHG----SAGIGATK----SSK-YVPLK-- >ARCH_Methanoculleus_marisnigri_JR1 Concatenation of 2 sequences MAHRI-------------------IAQN-------------------------------RGKGGPTY-RAPSHRYK---- AALRHAG-K--ND-ALVSGNVIDIEHDPARHAPIALARLD-SGEKIYVLATEGLGVGDTVSWGT-G-GT-VKNGNTLPLG EIPVGAYVCNIEARPNDGGKFVRSSGVQALVIGKADD-GRVGIRMPSGKNKWFNGACMATVGIVAGGGRGEKPFVKAGKK -HFHVRSSSERW-P-RVKGVCMNVIDHPFGGGGHQH----CGRPKTVAR----GTSPGRKVGH-VAARRTG------KWK MPKINRPRRGSLAYSPRKRAKSPVPRYGSWPEGAPAVQG-FAGYKVGMTHVIMVDDHKSSPTEGKDVMVPVTVVEVPPMR VAGVR----AYG----E--DTYGKHALTEAW------TTD--LSRRINVPKNHDTAAALEAVAVGEGKVSELYALAYTRP MELTGVPKKVPDLMEMRI---AGGSLEDQIAY-----AAEILGK-EITISGN---LEVGEYVDVTAVTTGKGTEGPVKRW GVQV-RKRKHSRGGKKRH-IGNLGP--WHPH-HVRWQVPQMGQMGYQQRTEFNKRILKIGADGD---------EITPAGG FLHYGLVRGPYVLIKGS-VPGPNKRLVRIR--MKAQVRT-LTGEIA-HEIDLPE-IF-----REEY-RPDLIKRAVLALQ STRFQPHGTNPYAGM-----------RTSAESW----------GSGRGAAQVPRLK---NGSRV-AR-VP----QA---- TGGRAAHPPK-VEKILVKEINRKEKRKALRSAVAASTYPDLVRERGHLFEGDL---P-LVFEDRF---EEV--------- --TRTGLIV---TGG-------EPLRAARNLAGVD-A---------------VAVDQLNAELLAPGTQAGRLTIWTESAI RRLETAMKDIY--------------------------IDKVVVHMGVG----ESGERLVKAEDLVKQITGQKPVRTIAKR TQPAFGIRKGAPIGCKVTLRRENAEKFITTALDIIERR------LAP-SQFDRTGNVSFGIEEHTDFPGMS-----YDPT IGIYGMDVNVVLE-YKGARIARRSVERRKLPADQK-VNKEEAIAFMCENYRVEV--MAI-T--RQVEIPPGVDVT-L--- -D-G--G-VLTVSGPKGTLVRDM-RFP-Q--IDLMVEG-GE--VVV----S-T-ASEKKRIL-AMTGTLEAHAKNMIRGV ADGYEYRMKVVYSHFPIQLKQQG-NR--LEITNFLGEKQPRIAKI-I-E-GVTVKIG--N-D-EVTITG-IDKEKVGNTA ANIEHAT------RITKR---DPR-VFQDGIYITERV--MKAMQAKIPRALATGSRMVCSDNTGARLVEVVSVDG-VRRR QPCLGLGDVATVSVKKGTPD-----------MRRKLEKAVVIRQKKEIRRPNGIRLSFEDNAMVLIN-ERGE-PKGTEIK GAVPREI--AERFPKIASMATTIVMP-V--N---------KRSKYRGS-RTCGGGTHKNRRGAGNRGGRGRAGQRDHR-- -FSHF-YLKGEIAN----GK-HG--FVSLDVGEIGDLIALDAA-----DK---------VLG--GGR-V-T-H-K-MSI- SAREFSERARMKIEEMGGQAMN--LAKKAYTRREYMGGVPGSKIVQFDMG----NLTEDYPVELSIVVDETCQIRHTALE AARIGINRQLQKEVG-RANFHLKIRTFPHHVLRENKQATGAGADRVSEGMRLAFGKAVGTAARVEK-GQKVFSVWTSP-- QYVDKAKVSLKRGIYKLPTPARI-VFVPFRRRHEGKTDYYKRMSLLSSGTPRMVVRKTNRQIIVQLVVP---EVEGDSTL VAAYSA-ELAG-YGYE----GST-ASTPAAYLTGMLFAVK--ALNAG-YGEAILDIGLARAKPGARVFAALKGAVDAGLD VPYGESILPDEERLKGAHIAEYAPE---------------------RAGDLVTNVEAVALAIENV-ARAKANELPVSPKH SIEIARFIKNMTTTEAKAYLTDVVALKKAIPFKRFNRNVAHKRGLS---KWPAGRYPVKAAEAYIRLLESVEKN----A- EYI--GLDVENLRIDHAAANTGRGLRAFFPRAMGRATPKRRETVNIEIVVTERTRVVKGDTVKVLRGD------FA-GDE GVVDAVDMKAC--RLV--VHGVMVTKADGT-------------------EVPRPVDPSNVQ-I----------------- --TKLNLKD---------------KLR---EERLGG---GA---MA-------------IE-K--------------K-- ---FITDGVRNVRVEKFL--TKELK-----RAGYGGMDIARTP-L-GTQVTIFAEKPGIVIGKGGKQVRQLTQDLATDPQ VEVQQVQN---PNFNAQIMAERLANALERGWYFRKAGSSTIRRIMES-GALGCEVIVAGKLTG-SRSRTQKFTEGYIKHC GEPSETIVEKGYALAIKKLGTIGVQVKIVMARLNPIADAMSTIKNAGDAGKGEVIVEPASKLLGAMLRVMQENGFISGFE FID----D---G----RGGQFRVQLSGT---INK-------C---GAISPRFPVAMADM---EYWESQYLPAKNFGILIV STSKGVISHAEARNEGIGGQLLGYVY--MQKARIRLSGTDFEKIEMVCDRIKEIAERTGVNLAGPIPLPTKKLVVPTRKS PDGEGTATWDRWQMRVHKRLIDI-DADERALRQLMRIQVPKDIGIEIVLGQVITGKVVSDRMNGTVVVEREFLHYVKKYK RYEKRRSRYHAHSTPC-INAGVGDVVRIAECRPLSKTTNFVVVE--VMTPRRREEFTYRGYSVADLQQMALSELLPLMPA RARRKF-DRGLSREHEKLLADLRSGDE------------NIRTHLRDMIIMPEMVGRSIEIHNGKEFQKVEIQP-EAVFH YLGEFALTRRRVAHG----SAGIGATR----SSK-YVPLK-- >ARCH_Methanopyrus_kandleri_AV19 Concatenation of 2 sequences MGKRI-----------------------------------RP---------------QRLGRGGPTY-RAPSHRYRGRIE HRPYDEQ----EKKGKVVGKVVELLHDPARNAPVARVRFE-DGEERLILVPEGTKVGDIIECGV-S-AE-IKPGNTLPLA EIPEGVPIFNIEGQPGDGGKFARAPGCYATIIAH--DVGRTYVQLPSGKVRTFDPRCRATIGVMSGGGKREKPFVKAGKK -YYHMRSKGGKW-P-KVRGVAMNAVDHPFGGGNHQS----PGKPTTIAR----GDPPGRKVGH-IAARKTG------RGG RRNPGRPRRGSLAFSPRKRASRPVPRIRSWPDERVRVQG-FAGYKAGMTHAIMIDDWPNSPTEGEEISVPVTILDAPPMY VAAIR----AYA----PTPDGY--RCVTEAW-------AEIPEMDR------VFTVPKDGEAELVDEGIVEEIRVIVATQ PKKAGVPKKKPDVMEYRI---GGKDVRERFEY-----AVEILSE-EIRA-KD-V-FDEGEIVDVSAITKGKGFQGVVKRW GVTI-QDRKTQRKQKGRH-IGSIGP--ITPS-RVRWTVPMAGQVGYHQRTEHNKRILKIGEDGE---------EVTPRGG FVNYGVVRGDYIMIHGT-VPGPKKRLIRVR--MEAPVFN-LEGEEV-DTVELPS-FF----E--EPVRKDLIRRAVLAAQ ANRRQPYGTDPRAGF-----------RTSAESWGAGHGVAVPRVKGRRHPA--------AGRA--AR-VA----QA---- VGGQKAHAPT-PEKDWTQRVNRKERRAALRSALAATAKPEFVKERGHVIDDVPHL-P-VVVVDEL---KSL--------- --NKARLIV--VDED---E---GIKLGARNHPGVD-V---------------VEAMHLGVEHLAPGAHPGRLTVFTPGAL EVLEMSVV---DEET----RRKILEDWE-SNPMRKPRVGKVTVNIGVG----ESGDRLQKAYELLQELTGQKPVYTRAKQ TNPSFGIRRGQPIGVKVDLRREQAIEFLDWTLDAVDRELHE-------SQFDEFGNVCFGLEEHIALEGVE-----YDPE IGIFGMDIAVTLE-RPGFRVMRRRRCRRPVPRRHR-LTKEEGIVFMEEEFDVEVGVIVM-E--ERVKIKDDVEIE-ISQR ED-R-RY-EVTVKGPKGEVTKEF-YYP-D--VYLWVED-DE--VVI----A-A-TRSNRRQK-AILGMIKAYIENMQKGV TEGHEYKLKLVYSHFPPEVKVDQ-KEGKVYIENFMGENVPRVAEI-VDPENTEVIVQ--G-Q-DIIVRG-IDKEAVGQTA ANLEQAT------YIKDR---DPR-VFQDGIYIVEKDGKKAIKAKSPHAALPVGARLVCADNTGARELQIIAVKG-VRRR LPNAGIGDMVVCSVKEGTPD-----------MRKEVVNAVIVRQRKEYRRPDGTRVKFEDNAAVIVT-PDGA-PRGSEIR GPVAKEA--AERWPRIGSIASIIV------MVVRRKK---KSPKKYRGSRTHGGGSHKNRRGAGNRGGRGMAGSH-K--- -HKWF-HVIKYMPD--HFGK-RG--FNRINVGELGDKIVIDVTDERLKDK---------VLG--GGH-V-K-R-P-LVV- VAPEFTERAVEKLEEAGGEAME--WKGPAYTRREYIKGVPDPKIQQFDMG----NPAGDFDVEVSLVARERAQVTHNALE AARVAANRYLTKTVG-RQNYHLKIRVYPHHVLRENPLATGAGADRVQEGMRLAFGKPIGTAARVRE-GQRVVTVRIDP-- ENFEHAKEALRRAGMKFPFPFTI-VRVPFRRRREGKTNYYKRRELIKADAPRLVARKTLNHNIAQIVDF---APHGDVTL ASAHSI-ELRNKFGWK----GHC-GNTPAAYLTGYLCGLR--ALERG-IERAVIDIGLHRPVRGSRVFAMLKGALDAGMD IPHGEEVLPPEDRIRGEHIANLARQIKEEDPEEYERRFSKYLERGLKPEELPEHFEEVKSKIERT-AKAFIRELRISPKH AREICRAIRGMPLDRAKEFLRRVIRKEEAVPFRKHKKKVPHRRQIRP--GWDAGRFPEKAAREILRVLEHAEAN----A- EYK--GLDTDRLYIKHIAAHKGRVIRGWIPRAFGRATPFNTPTTHIEVILEESLPVRRGDMVRIMRGD------FK-GHE GEVVEVDLKRL--RIY--VEGATIERANGE-------------------KVYYPIHPSNVM-IIEPNL-------DD--P MRRKIIERS-------------GGEVE--AVPEKSEEEKEEKM-YGENVP---------VH-K--------------K-- ---FVQYGMLKTELDEYL--EEELG-----RAGYGGMRLQRVP-N-ATKIIAYVERPAIAIGRRGRNIRRVEEEVQERVS IEVKELPS---PELNPRVVARRLASALERGIHFRRAAYGALRRIMNA-GAKGAMIILSGKLIGA-RARTEKFMEGAVKYC GEPGDEYMIEGYVQAVTKPGAIGVTVRIMMTLMDPLADAMATIKNNEMVGNKECVIEPASKLIGRVLKVMQEYGYIGSFE FID----D---G----RSGKFLVKLVGR---IND-------C---GVIKPRHPVKKDE---WEYWEQRYLPARDFGLLIV TTPEGVMSHYEAKERGIGGRLLAYVY-MAQEVRLRLSSTDHYKLEEVCERIKKVVEETGAQMSGPIPLPTKRLLVPTRKS PDGEGKATWDKWEMRIHKRLIDI-KGDERTIRRLMRIHIPEEVHVEIIMGMILEGVVVSDRMDKTVIVEREYYRYDRKYE RWERRRSRIPAHNPPC-IDAQEGDKVRIAECRPLSKTKSFVVIEVLERAEKEWVEFRYRGYTLGELMKMPIEEFIELLPA RQRRSL-KRGLPSRHKKLLRKVRRARRLLRRGKKP---PVIRTHCRDMIILPEMVGLTIAVYNGKEFKEVKIEP-EMIGH YLGEFAKTRKTVEHG------GIGATR----SSL-FVPLK-- >ARCH_Methanosaeta_thermophila_PT Concatenation of 2 sequences M----------GKR----------IISQ------------------------------NRGKGTPTY-RAPSHRYR--AD IKHIKFS-G-----DLVRGIVEDIMHDPARTAPVALVRLE-NGEKQYVLATEGTYIGQEIACGP-A-AE-IQPGNTLPLA SIPEGMPICNIESKPGHGGQFARASGVYGILVAH--DVGATVVQLPSGEMKWLNPNCLATIGVVAGGGRTEKPLVKAGKS -FYKYRSKAVKW-P-RVRGVAMNAVDHPFGGGGRQH----PGRPKTVSR----GTPPGRKVGS-IAARRTG-------KR MATIHRPRRGSLAFSPRKRAKSEVPRIRSWVAERAGMAG-FAGYKAGMTHVIMIDDRPRSLTEGMEISVPVTVVEVPPMS VAALR----VYE----PYNGGI--RPAGELW------AENLSQIPK----------ARRGASESRVDELCEIRVLAHTNP RLLTGVPKKVPDIMEIPV-----TGRSVEEQLKAAEGLL---GS-QVAV-SN-I-FNVGEWIDVSAVTKGKGTQGPVKRW GIML-QKRKHSRTGKLRH-VGNLGP--WHPA-RISWRVPQLGQTGYHQRTEFNKRIMAIGTNGT---------DITPDGG FVGYGVVRNEYMLIKGS-VPGPVKRLVRMR--MNAKIID-ISGNPV-GEIVLPA-IF----DE-EY-RPDLIKRAVLAAQ ANRLQPYGPHFYAGM-----------NTSARSW----------GPGHGVSRVPRIVTG-RRA---AA-VP----MA---- RGGRASHPPV-PSKVLSEKINEKERIKAIRSAVAATAKPDIVAARGHLFSGEL---P-IVVRGEI---ESI--------- --SKTSLIV---AAAD--N---GIGRAARNLPGVD-F---------------VTADRLNAELLAPGTHAGRLTVWSEPSL KVLEMNLE---------------------------PRIGKVVVHIGVG----ESGQRLVNAETILSEITGQTPIRSRAKK TLPAFGIKKREPIGTRVTLRGRAAEEFLETAFKVAGGVIKK-------SQFDENGNFAFGIEEHTDFPGMK-----YDPE IGIFGMDVAVSLM-RAGYRVAERRVARRKLPNSHK-VKRDEAVEFVQKRFGVRVMVEEV-V--RRLDIPDGVDVQ-I--- -S-G--R-SVRVKGPKGELSREL-WYP-D--IEIKRED-SK--ILI----R-S-VARKKQHL-AMVGTIAAHIKNMIRGV TDGFEYRMRVVYSHFPIQVKVAD-GK--VAISNFLGERKPRFATI-V-G-DVNVEVG--K-D-EILIRG-MDKEAVGQTM ANIEQAT------RVRGF---DVR-IFQDGIYLVEKR--MRGNKAKIPRSINTGTYLECADNTGARTLFVVSVKG-VKNR QPCAGIGDMVVVSVKKGTPE-----------MRKQIFNAVIIRQKKEFRRPDGLRVKFEDNAAVITD-DAGV-PKGSEIK GPVAREV--AERFGKIASSAAIIV-------MVR------EHTKKKRG-HRTYHGKHKNQRGGGSRGGRGNAGTC-K--- -HHWVRSIIRGEPM----GK-HG--FVRINVGVLVGPEGRIEL-----VK---------VLG--KGK-V-T-R-R-LTV- AAAAFSSSARSKIEAAGGEALR--IERP-YTRREYIGGVPGSKVVHYDMG-NLT-E--EFPVKLSLVVREPCQIRHTALE AARVAANRYLLKTLG-RNDFHLKLRVYPHHVIRENKQATGAGADRVSSGMRRAFGKPVGTAAQVYT-GQRIFTLGVHP-- EHIEEAKTALRRAGHKLPSPVQI-IRVPFRRRREGRTNYHVRYRLILSRKPRVVVRKGNANITIQLIIA---ELKGDRTL LTVSSK-ELRN-YGFQ----HST-GNVPAAYLTGLLFGKK--MLALG-YNEGILDIGLHSNSRGSRVYAALKGVVDAGVD VPHSPEVFPDDSRIRGEVIRDY------------------------TGVDVVSQFEAAREKIGRF-ARAMGVELPISPKH AREICRAIRGMKVEAAERFLQDVIALKRAVPFRRYNRNVPHRHGLV---GWPAGRFPQKAARAVLRVLENAIGN----A- EYK--GLEKERLVIGYANTKKGRTFRGWMPRAMGRATPKNQETVSIEMILTESAQVKKGDTVKVMRGD------NA-GVE GEVLSVDLKRC--VIT--VAGVSNFRADGT-------------------EVPRPIHPSNVM-ITKLDL-------DD--- ----------------------DEREK---IFSR----------MA-------------VE-K--------------K-- ---FVQEGFTKALVDEYL--AKELD-----RAGYGGMVMNRTP-M-GTQITVYAEKPGMVIGKGGKLIRKLTRDLERRPQ IDVQDVGK---SDLNARVVANRLASSLEHGWYFRKAGQSMLRRVMDS-GALGCEIVISGKLTG-PRSRVEKFLAGYIKHS GKPAEEIVDTGYAVAVKKLGAIGCQVRIV-MLLDPLADAMSTIKNAENVGKPECIIKPASKLIAMTLKVMADLGYIGEFE FID----D---G----KSGMFKVKLLGR---INR-------C---GVIKPRFAIKVAEL---EKWERRFLPARNFGVLIL STSQGVMPHTDARARGIGGHLLAYVY--MQKARIRLSGTNPATLDEICNQVRGIAQRTGVHMAGPIPLPTKRLVVPCRKS PDGEGSATWDHWEMRVHKRLIDL-DADERALRQLMRIQVPKNVNIEIVLGQVLEGIVVSDKMARTVVVMREFKKRITKYE RYEKRRSKIHAHNPPC-LDAKVGERVRIAECRPLSKTKSFVVVEVM---PKRKEEFTYRGYRVSELAKMRLEEIAELLPS RQRRTL-RRGLSKEHRKFMAKLRARGT-------------AKTHLRDAIVLPEMVGKVVEIHNGKTFQRVEIIP-EMIGH YLGEYALTRARVIHG----AAGVGATR----SSK-FVPLK-- >ARCH_Methanosarcina_acetivorans_C2A Concatenation of 2 sequences M----------GKR----------LISQ----------------------------N--RGRGTPTY-RAPSHKYK---- -ADLRHP-RV-DENSSLRGEVVGIEHDPARSAPIAKVAFE-NGEELFLLASEGIAVGNIIECGD-D-AE-VKPGNIVPIG NVPEGFFICNVESKPNDGGKFVRSSGVYATVVTH--EATRTAVSMPSGNIKWLNPKCRAVVGIVAGSGRVDRPWLKAGKK -YHKMKTRAAKY-P-RVSAVAMNPRDHPFGGGAWKH----PGKPTTVSR----NAPPGRKVGL-IAARRTG-----MKR- MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEGEPKLQS-FAGYKVGMTHVIMVDDTKNSLTQGMEISVPVTVIETPAIR VAAIR----AYA----EDSTGE--KAIAEVW----AADLDPELIPI----------PAAGNQLIEEGRVSDVRAVIYTLP KSLTGVPKKVPDIMESGI-----SARDLGTKFEYSKTIL---GT-LVSV-TD-V-FKNGTLVDTAAITIGKGTQGPVKRW GIQL-MKGKHSRQGSLRQ-VGTLGA--FNPS-RVSWRVPQMGQMGYHQRTEFNKRILKIGSDGE---------EVTPEGG FINYGLVRGDYILIKGS-VPGPSKRLIRLR-MATAKTID-LTGKAV-GEVELPA-VF----DA-DY-RPDLIKKAVLAAQ ANRLQPYGPRLYSGM-----------ETSARGW----------GSGRGVSHVPRLVNS-SRA---AR-VP----HA---- KGGRRAHPPK-PEADRSEKVNTKERRYAIRSAIAATTDPTLVSLRGHIFEAEL---P-IVAVNDL---ESL--------- --ERTKLIV--AGENT------PILKAARNLSGVD-V---------------VTVDSLNAELLAPGTHAGRLTVWTESAI GKLE----------------------------MRTPIVEKVIVHMGVG----ESGQHLVNAEDILRNITGQEVVRCFAKR TLPAFSIKKNEPIGCKVTLRGQKAQEFLETALGIVEKTLNR-------SQFDSFGNVSFGIEEHTDFPGMR-----YDPN IGVFGMDVTVVLK-RPGERICKRRIAARKIPAGHR-VTVDDAIAFLNESYGVEVMVKEI-A--RTIEIPEGVSVS-L--- -A-Q--D-VFTATGPKGTVERKL-WYP-G--IMIDVKD-GE--VVV----D-A-EYARKEQK-AMVGTFASHIRNLVKGV NEGFECKMSIVYAHFPMQVKVDG-KT--LIIGNFLGEKKPRFAKI-I-G-ETKVKVS--G-N-DVTITG-INKEDVGQTA ANIEQKT------KIKRF---DPR-IFQDGIYIVQKA--MKGMRSNIPRALNAGAQIACVDNTGAKVVEIISVKG-VKNR MPCAGIGDMCVVSVKKGTPE-----------MRKQVLLAVVVRQKQEFRRPDGLHVSFEDNAMVITD-EEGI-PKGTDIK GPVAREV--AERFPKIGTTASIIV----------------MDTKKFRGSRTCGGGTHKNRRGAGNRGGRGKAGGC----- -KHHF-V-RAMMR-GYSYGK-HG--FKRVNVGELEGLAEVKDGAYHINEK---------VLG--SGR-V-T-K-N-LVV- TSEEFSASAREKIENAGGSCMN--VRQRSFTRRKYMGGVPGSQVIHYDMG---DKANTSFPVKISLIVEEKCQIRHTALE AARITANRHLVADTG-KMGFYMKLRVYPHEVIRENKQATGAGADRVSSGMRRAFGKNVGTAARVKP-MQKIFTVAVEK-- QNFKAAKEALWHAGQKLPTPCRI-VKVPFRRRREGRTNYHLRLKLLLSRQDRVVVRKSSRNVQIQLIAP---TPDGDITY SSAVSN-ELAK-YGYT----GAT-GNTTAAYLTGLLFGLK--SLQKG-YEGGILDIGLQASSAGSRVYAALKGVVDSGFE IPCSPEVFPPDERIRGEHIAGYRE----------------------ESSDLPEQFEATKEKIETT-SKAMGSELHISPKK SREVCCKIKGMKASEARKFLEDVIAMKQAVPFKKHHDGSGHRKGPM-----AAGKYPISASKEILKVLKNAESN----A- EYK--GLEPANMYIIHAAIQRGRVIHGFMPRARGRATPKDTETVNIEMILSESAAVITGDTVKVMRGD------FK-GTE GKVQSVSLMDG--TIT--VDGVISTKVDGT-------------------EVPRPLNPSNVM-ITKLEM-----------K ----------------------DGRRA------------SSI--MA-------------IE-K--------------K-- ---FVNDGYVKASMDEYF--AEQLS-----RAGYGGMELNRTP-M-GTQIVIYSEKPGMVIGKAGKVIRKLTRDVANKPQ IDAQEVKR---PELNAQMMASRLAASIERGWYFRKAGHNTLRAVMNA-GALGCEVVISGKLTGA-RSRVEKFVDGYIKHS GNPVEEVVDEGFAVAVKKLGTLGCKVRIIMVLLDPLANALSTIKNAEAIGKSSCVVRPASKNIGNVLKVMQDLGYIGDFE FID----D---G----KAGIYSVTLVGR---INK-------C---GAIKPRYSV---GTASFERWEKQFLPAKNFGALIV TTSSGVMSQYEARDKKIGGQLLAYVY--MQKARIRLSGISPKDLDGVCNQVKSIAERTGVNISGPVPLPTKKLVVPTRKS PSGDGTATWDHWEMRVHKRLIDI-AADERALRQLMRIQVPKDINIEIVLGQILKGIVISDKMTKNIVMKRYREKWSYKYQ RKQRVSSKIHAYSPPC-MEAKIGDIITIAECRPLNKGSSFVVIENKSNIPKRKGEYTYRGKTVSELQELSLEEFAELLPS RERRSL-KRGFTDGQKKVLHEFKEGKK-------------IRTHHRDMIILPEMIGKTIEIHNGKGFVSVDLQP-EMVGH RFGEFAPTRSRVSHG----SAGVGATR----SSK-FVPLK-- >ARCH_Methanosarcina_barkeri_fusaro Concatenation of 2 sequences M----------GKR----------IISQ------------------------------NRGRGTPTY-RAPSHKYKAELR HPRVDEN-------TSIQGKVINLEHDPARSAPIAKVVFE-TGEERLLLASEGIAVGSTIECGD-D-AD-VRPGNIVPIG KVPEGFFICNIESKPNDGGRFVRSSGVYATVVTH--ESNRTAVAMPSGNIKWLNPKCRAVVGIVAGGGRVDRPWLKAGKK -YHKMKTRAAKY-P-RVSGVAMNPVDHPFGGGAWKH----PGKPTTVSR----NAPPGRKVGL-IAARRTGKR------- MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPERLQ---G-FAGYKVGMTHVIMVDDTKNSLTQGMEISVPVTIIETPAIR VAAIR--AYAED----T--AGE--KAIAEVW------ATD--LKRRIPVPKGDNMAETLGNIMIEEGKVSDIRAVTYTLP KSLTGVPKKTPDIMESGI---SARDLNTKFEY-----AKSILGT-LVSI-TD-V-FKTGTLIDTAAITIGKGTQGPAKRW GIQL-MKGKHSRQGSLRQ-IGTLGG--FGLR-RVSWRVPQMGQTGYHQRTEFNKRILKIGSDGE---------EVTPEGG FINYGLVRGDYVLIKGS-VPGPSKRLIRLR-MATAKTID-LTGKVV-REIELPD-VF----DV-DY-RPDLIKKAVLAAQ ANRLQPYGPRLYAGM-----------ETSARGW----------GSGRGTSHVPRLVNS-SRA---AR-VP----HA---- RGGRRAHPPK-PEADRSEKVNTKERRYAIRSAIAATRDPTLVSLRGHIFEAEL---P-IVTENAL---EDL--------- --DKTKLIV--AGESA------PILKAARNLSGVD-V---------------ATVDSLNAELLAPGTHAGRLTIWTESAV EKLE------------------------MSNVMRTPVVEKVIVHMGVG----ESGQHLVDAEEILRNITGQEVVRCFAKR TLPAFSIKKNEPIGCKVTLRGQRAQQFLETALGIVDKTLVR-------SQFDSLGNVSFGIEEHTDFPGMK-----YDPN IGVFGMDVTVVIK-RPGERICKRRIATRKIPTNHR-VTLEDSIAFLNDSYGVEVMVKEI-A--RKIEIPEGISVS-F--- -S-Q-DD-VFTATGPLGTVERKL-WYP-G--IKIYVRD-GE--VEV----D-A-ESSRKEQK-AMVGTFTSHIKNLMKGV NEGFECKMTILYAHFPMQVKVDG-KT--LIIGNFLGEKKPRIAKI-L-G-ETKVKVS--G-N-EVTVSG-INKEDVGQTA ANIEQKT------KIKRF---DPR-IFQDGIYIVQKP--MKGIRSNIPRALNAGAKVPCVDNTGAKVVEIISVKG-VKNR MPCAGIGDMCVVSVKKGTPE-----------MRKQVLLAVVVRQKQEFRRPDGLRVSFEDNAMVITD-EEGI-PKGTDIK GPIAREV--AERYPKIGTTASIIV----------------MDTKKFRGSRTCGGGTHKNRRGAGNRGGRGKAGAC----- -KHHF-V-RAMFR-GYSYGK-HG--FNLVNVGELEGLAEIKDDAYHINEK---------VLG--SGR-V-M-K-N-LVV- TSEGFSASAREKIEAAGGSCMN--VRQRSFTRRKYMGGVPGSQVIHYDMG---DKANTSFPIKLSLLVEEKCQIRHTALE AARITANRHLIEDTG-KMGYYMKLRVYPHEVLRENKQATGAGADRVSSGMRRAFGKNVGTAARVNP-FQKIFTVAVEK-- QNFVAAKKALWHAGQKLPTPCRI-VKVPFRRRREGRTNYHLRLKLLISKQDRVVVRKSARNVQIQLIAP---TPEGDITY SSAVSS-ELAK-YGYT----GVT-GNTTAAYLTGLLFGLK--SLKKG-YEGGILDIGLQASSAGSRVYAALKGIVDSGFE VPCSPEVFPSDERIRGEHIAEYRE----------------------ESSDLPEQFEATKEKIETT-SKAMGSELHISPKK SREVCCKIKGMKVPEARKFLEDVIALKQAVPFKRHHDGSGHRKGPM-----AAGRYPVSASKEILKILRNAESN----A- EYK--GLEPANMYITHAAIQRGRVIRGFMPRARGRATPKDTETVNIEMILSESAAVIAGDTVKVMRGD------YK-GTE GKVQAVSLQDG--TIS--VDGVISTKVDGT-------------------EVPRPIYPSNVM-ITKLEL-------KD--- --ERRASSI---KK------------------------------MA-------------IE-R--------------K-- ---FVNDGFVKASMDEYF--AEQLN-----RAGYGGMELNRTP-M-GTQIVIYSEKPGMVIGKAGKVIRKLTRDVAARPQ IDAQEVKK---PELNAQMMASRLAASIERGWYFRKAGHNTLRAVMNA-GALGCEVVISGKLTGA-RSRVEKFVDGYIKHS GNPVDEVVDEGFAVAIKKLGTLGCKVRIIMVLLDPLANALSTIKNAEAIGKSSCIIRPASKNIGNVLKVMQDLGYIGEFE FID----D---G----KAGIYSVTLVGR---VNK-------C---GAIKPRYSV---GTGSFERWEKQFLPAKNFGALII TTSSGVMSQYEAREKKIGGQLLAYVY--MQKARIRLSGISPKDLDGVCNQVKSIAERTGVNISGPVPLPTKKLVVPTRKS PSGDGTATWDHWEMRVHKRLIDI-AADERALRQLMRIQVPKDINIEIVLGQILVGTVVSSKMDNTVVIERQYMKLVPKYQ RYEKRRSKVHAHNPPC-ISAKVGDIVTIAECRRISKTKSYVVVK--EVPPKRKGEYTYRGKTVSELQELSLEEFAELLPS RERRSI-KRGFTDGQKKVLHEFKEGKK-------------VRTHHRDLIILPEMIGQTIEIHNGKGFVSVDLQP-EMIGH RFGEFAPTRSRVSHG----SAGVGATR----SSK-FVPLK-- >ARCH_Methanosarcina_mazei_Go1 Concatenation of 2 sequences M----------GKR----------LISQ----------------------------N--RGRGTPTY-RAPSHKYK---- -ADLRHP-RV-DENTSLQGEVIDIEHDPARSAPIAKVAFE-NGEELFLLASEGVAVGNIIECGD-D-AE-VKPGNIVPIG NVPEGFFICNIESKPNDGGKFVRSSGVYATVVTH--EPTRTAVSMPSGNIKWLNPKCRAVVGIVAGGGRVDRPWLKAGKK -YHKMKTRAAKY-P-RVSAVAMNPRDHPFGGGAWKH----PGKPTTVSR----NAPPGRKVGL-IAARRTG-----MKR- MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEGEPKLQS-FAGYKVGMTHVIMVDDIKNSLTQGMEISVPVTVIETPAIR VAAVR--AYTED----S--TGE--KAIAEAW-AA---DLDSELIPI----------PAAGNQLIEEGRVSDIRAVTYTLP KSLTGVPKKVPDIMESGI--SAK-DLGAKFEY-----AKSILGN-LVNV-TD-V-FKNGTVVDTAAITIGKGTQGPVKRW GIQL-QKGKHSRQGSLRQ-IGTLG-S-FNPS-RVSWRVPQMGQMGYHQRTEFNKRILKIGSDGE---------EVTPEGG FINYGLVRGDYVLIKGS-VPGPSKRLIRLR-MATAKTID-LTGRTV-GEIELPA-VF----DA-DY-RPDLIKKAVLAAQ ANRLQPYGPSLYAGM-----------KTSATGWGSGRGVSVPRLKNSSRA---------------AR-VP----HA---- KGGRRAHPPK-PEADRSEKVNTKERRYAIRSAIAATIDPTLVNLRGHIFEAEL---P-IVAVNDL---ENL--------- --ERTKLIV--AGENS------PILKAARNLSGVD-V---------------VTVDSLNAELLAPGTHAGRLTVWTESAI GKLE------------------------VSNPMRTPMVEKVIVHMGVG----ESGQHLVNAEEILKTITGQEVVRCFAKR TLPAFSIKKNEPIGCKVTLRGQRAQEFLGTSFEIIE------KTLSR-AQFDSLGNVSFGIEEHTDFPGMR-----YDPN IGVFGMDVTVVLK-RPGERICKRRIATRKIPTDHR-VTVDDAIAFLNESYGVEVMVKEI-A--RTIEIPEGVSVS-L--- -S-Q--D-VFTAKGPKGTVERTF-WYP-G--IKIEVRE-GE--VVV----D-A-ESSRKEQK-AMVGTFASHLKNLIIGV SEGFECKMNIVYAHFPMQVKVEG-KT--LVIGNFLGEKKPRIAKI-L-G-ETKVKVS--G-N-EIVVSG-INKEDVGQTA ANIEQKT------KIKRF---DPR-IFQDGIYIVQKA--MKGIRSNIPRALNAGAQIACVDNTGAKVVEIISVKG-VKNR MPCAGIGDMCVVSVKKGTPE-----------MRKQILLAVVVRQKQEFRRPDGLHVSFEDNAMVITD-EDGI-PKGTDIK GPVAREV--AERFPKIGTTASIIV------MDIKKFRGS----------RTCGGGTHKNRRGAGNRGGRGKAGGC----- -KHHF-V-RAMMRG-YSYGK-HG--FKRVNVGELEGLAEVKDGAYHINEK---------VLG--SGR-V-T-K-N-LVV- TSEEFSASAREKIENAGGSCMN--VRQRSFTRRKYMGGVPGSQVIHYDMG---DKANTTFPVKISLVAEEKCQIRHTALE AARITANRHLVADAG-KMGFYMKLRVYPHEVLRENKQATGAGADRVSSGMRRAFGKNVGTAARVNS-MQKLFTVAVEK-- QNFPAAKKALWHAGQKLPTPVRI-VKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAP---TPEGDITY SSAVSS-ELAK-YGYT----GAT-GNTTAAYLTGLLFGLK--SLQKG-YEGGILDIGLQASSAGSRVYAALKGIVDSGFE IPCSSDVFPSDERIRGEHIAEYRE----------------------ESSDLPEQFEATKEKIENT-SKAMGSELHISPKK SREVCCKIKGMKASEARKFLEDVIAMKQAVPFKRHSEGAGHRKGPM-----AGGRYPVSASKEILKVLKNAESN----A- EYK--GLEPANMYIIHAAIQRGRVIHGFMPRARGRASPKDTETVNIEMILSESAAVITGDTVKIMRGD------FK-GTE GKVQSVSLMDG--TIA--VDGVISTKVDGT-------------------EVPRPINPSNVM-ITKLEM-----------K ----------------------DGRRA------------SSI--MA-------------IE-K--------------K-- ---FVNDGYVKASMDEYF--AEQLN-----RAGYGGMELNRTP-M-GTQIIIYSEKPGMVIGKAGKVIRKLTRDVATKPQ IDAQEVKK---PELNAQMMASRLAASIERGWYFRKAGHNTIRAVMNA-GALGCEVVISGKLTGA-RSRVEKFVDGYIKHS GHPVEEVVDEGFAVAIKKLGTLGCKVRIIMVLLDPLANALSTIKNAEAIGKSSCIVRPASKNIGNVLKVMQDLGYIGDFE FID----D---G----KAGIYSVTLVGR---INK-------C---GAIKPRYSV---GTGSFERWEKQFLPAKNFGALIL TTSSGVMSQYEARDKKIGGQLLAYVY--MQKARIRLSGISPKDLDGVCNQVKSIAERTGVNISGPVPLPTKKLVVPTRKS PSGDGTATWDHWEMRVHKRLIDI-AADERALRQLMRIQVPKDINIEIVLGQILVGTVVSSKMDNTVVIERQYMKMVSKYQ RYEKRRSKIHAHNPAC-ISAKVGDIVTIVECRPISKTKSFVVVK--EVPPKRKGEYTYRGKTVSELQELSLEEFAELLPS RERRSI-KRGFTDGQKKVLHEFKEGKK-------------IRTHHRDMIILPEMIGIAIEVHNGKEFVNVELQP-EMIGH RFGEFAPTRSRVNHG----SAGVGATR----SSK-FVPLK-- >ARCH_Methanosphaera_stadtmanae_DSM_3091 Concatenation of 2 sequences M----------GKR----------LIIQ----------------------------R--RGRGTPTY-RSSSHRFRGKVA YRSYDKL----EREGSLTGIVIDIIHDPGRSAPVAVVKFD-NGEEKLVLAPESIAIDDEIECGV-S-AS-IEPGNTLPLS EIPEGTPVFNIENNPGDGGKFVRSSGTYASLITH--DVDKTMIEMPSGELKAFNPRSRATVGVVAGGGRKEKPFLKAGNR -YHALKAK-GKK-MMTVRGVAMNAVDHPHGGGNRQH----PGRPTTISR----HAPAGRKVGS-IAAKRTG------KRR MTRHHQPRKGSVAFSPRKRVARETPRVSTWPEGLL---A-FAGYKVGMTHVTALDSRKGSPTENMELSVPVTILEAPPLV VLGIR----AYT----K--TTYGLKTLTDVI------ANDNLDSRKISVPKFDDIEAKIEELK---IDDIDEIRVLIHTK PKLTSVPKKKPEVLEFGL---GGKSVEDKLEY-----AISILGK-EITP--QDV-FQEGEYTDAIATTKGKGVQGPVKRF GVRI-QYGKAARSGIERH-VGSIGP--WTPN-RTMWTVAMQGQMGYHKRTEYNKKLLKIGDESE-------VDLINPDGG FVKYGFVKNNYILVKGS-LPGPSKRLVVLR-MAKINVYS-LKGDIT-EEIELPE-IF----EE-EY-RPDVIKRAVISMQ TARIQPWGTDPMAGKRTTAESFGSGRGAAMVP----------RVKGSSKAA--------------F--VP----QA---- IGGRKAHPPR-VNTIYHEKINKKERTLAIRSAIAATANKELVEQRGHQVSELEQI-P-FVIDDEI---ETV--------- --KTTKLVV--VGND---R---GISLGARNHAGVD-V---------------VEVNNINAELLAPGTHAGRLTIYTKSAI EKLG-------------------------MNVMQKPFIAKATINIGVG----EGGEKLTRAEKLIETLVDQKPVRTYSKV TNPEFGIRKKQPIACKVTLRGEKADKIISMVLSGLENRIKA-------SQFDKEGNVSFGIREHIDIPGVK-----YDPD IGIFGMDVSVTFQ-KPGHRIKERRLRPKKLPQAQR-VTKEESMEYMKENFNVTIKLADI-T--EIIPIPEDVTVT-I--- -N-G--S-EVTVKGNGGEIKRNF-NHN-K--ITISNDE-EN--VTV----K-V-AFPNKKDK-AMVGTIRSHISNMIYGV DHGFTYKMKIVYAHFPMTVKVQG-KI--VTIDNFLGERSPRKAKI-I-GDDVKVSVK--G-E-DVTITG-INKEHVGQTM ANIEQAT------KIKGR---DPR-IFQDGIYLVDKRQEMKAITSNVSKSLPIGARLKCIDNTGAREVEIISVKG-VRRR LASAGVGDMVVISVKKGTAD-----------MRREVTTAVVVRQKKEYRRADGLRVKFEDNAAVIIT-EDGV-LKGSEIR GPIAKEA--ADLWPAIGSAASIIV-------MIRKT----KKIRKQRGSRSVGGGCTKKRRGAGHRGGRGQAGGNKHH-- -WTWM---VINDPK--HFGK-YG--FKRINLSVILADEIAVKEDGQIVNK---------VLG--KGS-L-S-T-A-ITI- KAPKFSQSAISKIEDAGGIA----------TRKDYIRKIPASKIVQYDMG----NLSGEFPLEVTLAVKEHTHLSHNSLE AARIAANRYLQRTTG-KLGYRLKIRTYPHHIVRENPMATGAGADRVQSGMRGAFGKAVSSEALVRA-NQKIITAYVQV-- KDFEKAKVALNRAAMKLPVTCKL-VKVQFKRRREGKTNYNKRYKLVDLDKTRMVVRITSNHTITQLVKI---GENGDETL VSATSK-NLKE-FGWL----GNG-KNTSAAYLTGYLFGKK--ALNEG-YDETILDIGVQPSIKGTKIYAVLKGALDAGLY IPHNDSILPEDSRIRGEHIAQYAESM---DDDEKNAKFANYIRCGLSPEEIPDHFESVKNKIEKI-AKAAGHSLKISPKH SVEICRTIRNMYLEDAKAFLEDVIAKKTVVPFKRHNKKVGHRSDLK---GWPSGRYPVKAAAAILKVLENAEAN----A- ENE--ELDVENLKLVHVCANRGVIIRGWTPRAFGRASPSNTPTTHIQIVLGESFPVRKGDSVEIVRGD------FR-GTE GKVEGVDLKNY--RVL--VDGASSQKQDGS-------------------KLYQPIHPSNLV-LTEIYL-------DD--- --ERRNQAL-------------NRKV------------------M--------------IE-K--------------D-- ---FVKEGLKRTRIDEYL--ETKLE-----RAGYGGMDIQVTP-V-GTMVIVYAEKPGMVIGRGGKTVRAITKTLKNNPQ VEVKEVDV---PELNPRIMAHKVVAMLQRGMQFRRVAYSIIRRIMSA-GAQGVEVTISGKIRGS-RSACAKFNEGYIKKC GEPSIKYVKEGFATVQLKPGVLGIYVRIMMSLMDPLADALTNIRNNELQGNDSCVIKPASKLIGHVLSTMQKENYIGNFE LVD----D---G----KAGIFNVELVGN---INK-------C---GVIKPRHAVKNTEFEDYEKR---YLPAKNFGILIV TTPQGVMTHHEAKEAGIGGRLLVYVY--MNKARIKLTGTDPEKIADVCNQLKKIAERTGVDLSGPIPLPTKKLVVPTRKS PDGEGKATWEKWELRIHKRLVGI-EADERAMRQVMKVNVPDNVSIEIELGQVIEGTVTSDKADRTITVERSFYKYINKFE RYEKRNSKIKAHKPDC-LDVKVGDSVKIAECRQLSKTKHFVLVEV-KEG-MARKIFKFRGYTLEELQEMSLDEVIELLPS RQRRSL-KRGFLPRQEKVLDKMEKVKD---MKNDSGRPIVIKTHCRDMIVLPNMVGYTFGIYNGQEFVEVTIQP-EMIGC YFGEFAQTRGRVQHG----DPGMGATR----SSM-FVPLK-- >ARCH_Methanospirillum_hungatei_JF-1 Concatenation of 2 sequences M-------------GHRITTQ-------------------------------------SRGHGGPTY-RAPSHRYK---- AALKHLG-R--AG-ETVSYKIIDIEHDPARHTPIALVDVP-DGENTYVLVTEGMGIGDVLTWGA-D-AE-IRNGNTLPLQ EIPTGSSVCNIEAYPNDGGKFVRASGVQATVTDK--MEGRVAVRMPSGSTKWFNGQCRATIGIVAGGGRSEKPFVKAGKK -YHKMKNTASNW-P-RVRGFAMNVIDHPFGGGGHQH----AGRPKTVSR----GTSPGRKVGH-IAARRTG-------RR MPTIHRPRMGSLAYSPRKRAKSPVPKYHAWPAGEPALQG-FAGYKVGMTHVIMVDDHAHSPNEGKDIMVPVTVIEVPDMR VAAIR----VYR----H--DTYGNHVLTEVW-------AD---AEKKI-----REALEADKID--------VVALTYTRP SVLTGVPKKVPDLMETRI---DGGSMTERFEY-----GLSMLGK-DFDI-RS-L-FKVGQYTDVTAITKGKGTQGPVKRW GVHL-RKRKHSRGKKERH-VGTLGP--WTPH-HVRWQVPMMGQMGYHQRTEFNKRLLKIGEDGA---------EITPEGG FINYGEVRARYVLIKGS-VPGPSKRLVRIR--MKAQVLT-LTGSVA-HEIELPP-VF----SS-EF-RPDLIKKAVIAQQ SRRYQPHGAYVYAGI-----------TASAVGW----------GSGRGVSHVPRLKNS-SRA---AK-VP----QA---- KGGREAHPPK-VEKVLIRNINQKEKRKALNSAIAATISPELVRSRGHVFTGSL---P-YVLSGDF---ESL--------- --KKTKLIV--T---G--K---ERLRAARNLAGVD-V---------------CLVDNLNVELLAPGTHSARLTLWTEDAV RKLG-------------------------MNPNRSVAVDKVVVHMGVG----EAGDKLVNAERIISEITGNTPVRSVAKQ TLPAFGIRKGAPISCRVTLRGEAAEKFLETSIKIVENKINS-------RAFDKQGNFSFGIEEHTDYPGQS-----YDPK VGIFGLDVTVVLK-RNGVRIARRHIQQKKLPLKQL-VTVEDAKLFLKDRYNVEV--MTV-E--RVVSIPSGVSVT-M--- -D-G--T-VLHVKGPKGNLQRDM-WYP-G--IEITIGS-ED--VRF----T-T-ESQKKAVT-SMVGTLASHCSNMCTGV TKGYLYSMKVVYSHFPIQIKVVG-ET--LEIVNFLGEKYPRSARI-L-P-GTTVKVG--S-D-EVTVTG-IDKEVVGSTA ANIERAT------RIRDR---DPR-VFQDGIYIVSRSEQMKGLGIKVPRAVSTGTKLTCADNTGARVVQVVSVFG-VRRR QPKLGLADIATVSVKKGTPD-----------MRRKLVRAVVIRQKKEIRRPSGLRLSFEDNAVVVVD-DKNE-PRGTEIK GPVAREV--AIRYPRIGSMATIIVMP-V--N---------KRSKYRGS-RTCGGGTHKNRRGAGNRGGRGRGGSR----- -DHKF-V-RGVVHANWTYGT-CG--FKHLDIGQILEQGTATRD-GDAIEK---------VLG--GGQ-V-T-S-K-MNI- TAEAFSQSAIQKIEAKGGHAMN--LAKKAYTRKEYMGGIPGVKVVHFDMG-NLT-S--EFPMEVSLVVDESCQIRHSALE AARMSINRKLNKELG-RMNYHLKLRTYPHHVLRENKQATGAGADRVSQGMRLAFGKAVGTAARCQQ-NQKIFTVFSNP-- ASVEKIKDALRHGGHKLPSPTHL-VFVAFRRRREGRTNYHARTRLVVATKPRMVVRKTNRHIICQIITA---HMEGDRTH VAANSS-ELRK-FGYE----GSL-NNTPAAYLTGMLLAVR--ALKAG-QEGAILDIGLHRATPGARVFAALKGAVEAGFD IPHNEEILPADERCKGEHIAEYAPD---------------------RAGNLPANVAATVDAIKDI-ARGRVNEAPISPKH AIEIAGFIRGMKLDDAAAYLEGVVALQKPIPFKRFNRNVPHRKGLV---GWDAGRYPQKASRVYLRLLNNVRKN----A- EYN--GLEGDQLRIVHVSANRGIRRRSFMPRAMGRATPKDRQTVNIELVVRESIRVIKGDTVKVLRGD------HA-GTE GLVDYVITRDA--RIV--VDGVSVKKADGT-------------------EVPRPVDPSNVM-ITDLNL------------ ----------------------EDKRR---EQKLSG---E----MA-------------VE-R--------------K-- ---FVADGVRKVRVERHL--GHELK-----RAGYGGMDLIRTP-L-GTQVTIFAEKPGIVIGKGGKVVRTLTQDLATTPQ IEVQQVDN---PNLNAQIMAERLASALERGWYFRKAGSSTLRRIMDS-GALGCEVVISGKLTGA-RGRVQKFTEGYIKHS GDPVNTLVDKGYAVAIKKLGVIGVQVRLIMARLNTVADAMSTLKNASDTGRAECIVQPAGRLIGELLRIMKEAGYIKEYT RIE----D---G----RGGQFKVVMSGL---INK-------C---GCISPRYSVS---LDEMEYWEQLYLPSKNIGMLMI STSKGVMGHHDARRNGVGGELLGYVY--MQKARIRLTGTDYQKVEEVCEKIKEIAERTGVNLAGPIPLPTRKLVVPIRKS PDGEGTATWDRWQMRVHKRLIDL-DADERALRQLMRTQVPKDIGIEIVLGQVITGKVVSDKMTGSVVVQRDYLHFVRKYQ RYEKRSSKIHAHNPPC-LHARVGDMVSIAECRPLSKTKTYVVVEVN-RAPRRKEEFTYHGYKIDELRAMSLEDLLPVMPS RARRKV-LRGWTIGEEKLLSDIRSNGS------------RIRTHQRDMIILPEMIGREIEIYNGKEFIRVELQP-ESVFH YLGEFALTRRRVTHG----SAGIGATR----SSK-FVPLK-- >ARCH_Methanothermobacter_thermautotrophicus_Delta_H Concatenation of 2 sequences M----------GKR----------LISQ----------------------------R--RGRGTPTY-RSASHRFKGKIK YRAYDSI-E--SE-GSLKGKVVDIMHDPGRTAPVARVKFE-NGEERLILAPEALMLNEEVECGV-K-AR-VKPGNSLPLS EIPEGTPIYNIENRPGDGGKLVRSSGTYASLITH--DADKAVIELPSGELKALNPQCRATVGVVAGGGRREKPFLKAGKK -YHALRAKGKKS-V-TVRGVAMNAVDHPHGGGNRQH----PGRPTTVSR----HAPPGRKVGS-IAARRTG-K-----RR MARHHQPRKGSVAFSPRKRAARETPRVKSWPQGLL---A-LAGYKAGMTHVMMVDNQKNSPTEGMEVSTPVTILEVPPLT VMAVR----TYE----KTSRGL--KTLGEVL------ATETKDKLT----------PPADDYRSNMEYVADVRVIVHTNP RL-ASVPKKKPEVFECGL-GGKTPEEKFEYAL-----EIL--GK-DVRA--SEI-FSEGAFVDAIAVTKGKGFQGPVKRW GIRI-QYGKAARSSKGRH-IGSLG-P-WTPS-RTMWTVPQAGQMGYHRRTEYNKQILKIGDASE-------ADLVNPDGG FVRYGLVRNDYVMIKGS-VPGPTKRLVVLR--MKIKVYS-LEGEAI-DEMELPE-IF----NE-EF-RPDVIKRAVLSAQ TARVQPWGPDPMAGK-----------RTSAQSY----------GAGRGVAMVPRIK---NGS-RAAF-VP----QA---- VGGRRAHPPR-PQKNYHERINRKERRLAIRSAVAATARKDLVEARGHRIENVPQL-P-LVVDDEL----SMI-------- --KRTALIV--VGDDK------GITRGARNHPGVD-V---------------VRVENLNAELLAPGTHPGRLTVFTRSAI EKLD-------------------------MNPMEEVRIFKVTLNIGVG----EGGEKLARAERLLEEMSGQKPVRTHSKV TNPEFGIRKKQPIACKVTLRGERAEKVLKMFLEGIGNRLKA-------SQFDEYGNVSMGIDEHIDIPGMK-----YDPE IGIFGMNLSVTFE-KPGHRINRRRIQRRKVPQKHR-VSREEAIEFMKEKFQVKILAALI-R--EEIPIPDGVDVT-I--- -D-G----GVTVKGPKWELSRKF-NHS-E--ISMAVED-DK--VVL----E-V-KFPKKKDK-AMIGTVRAHISNMITGV TEGFRYRMKIVYAHFPMSVKVAG-DK--VVIENFLGERHPRTARF-V-G-DTKVQVK--G-D-EVEITG-INKEHVGQTM ANIEQAT------KIKGR---DPR-VFQDGIYLVSKE--MKAIASKVTRALPVGARLQCVDNTGAREVEIISVRG-VRRR LAAAGVGDMVVVSVKKGTVD-----------MRREVLNAVIVRQKKEYRRPDGLRVKFEDNAAVIVS-PEGV-LKGSEIR GPVAKEA--ADRWPSVGSAASIIV-------MIRKR----RKITRMRGSRTVGGGCSKKRRGAGHRGGRGQAGGHKHH-- -WTWI---VKYDPK--HFGK-YG--FKRVNLAYLLERGVASEEDGMVVEK---------VLG--SGR-I-T-R-P-VHL- KAYEFSRSATEKIEEAGGKA----------TRREYIKKIPGSKIVQYDMG----NLSAEFPISLSVAVKAPTQITHNALE AARIASNRYMQRRAG-RMGYHLKIRVYPHHIVRENPMATGAGADRVQDGMRKAFGKPVSTVALVKK-NQKIITIETNK-- KNFKDAKEALRRAAMKFPVPCRI-VKLAFRRRREGKTDYRARYKMVETGKSRLVVRITTYHVIAQIINV---GMNGDETL VSAHSK-QLQK-MGWL----GGT-SNTAAAYLTGYLCGKR--ALKEG-IEEAVLDIGLRPAIRGSKVFAALKGAVDAGLN VPHGESVLPDESRIRGEHIMEYAESL---DEEELRKRFSKYLERGLSPVDLPEHFDEIKKRISGT-ARASATHLKISPKH AVEICREIRGMELEKAKKYLEEVIRMERPVAFKRYNRKVGHRRGLN---GWASGRYPVKAAGQILKVLENAEAN----A- EYK--GLDTEKLRIIHISSHRGPVIRGWIPRAFGRATPFNTPTTHVQIVLGESLPLRKGDKVEILRGD------FR-GHE GKVEKVDLKRY--RVY--VEGATIQKVDGT-------------------TVYFPLHPSNLR-IVDLNL-------DD--- ----------------------EKRIK---ILERKG--------L--------------IE-K--------------D-- ---FVVEGLRRTRIDEYL--EKELE-----RAGYGGMDVQVTP-M-GTMVVVYAERPGMVIGRGGKTVRAITQKLKNKPQ VEVKEVDV---PELNPKIMAHKIAAMLQRGMHFRRVAYTTMRRIMAA-GAQGVEVTISGKIRGA-RSATAKFTDGYIKKC GEPSVKHVREGFATVQLKPGVLGVYVRIMVTLMDPLANALTNIRNNEIRGNVKCRITPASKLIGRVLRTMQKEGYIGEFE YVD----D---G----RAGKFIVELEGN---INH-------C---GVIKPRHAVKKDE---FEKFEKRYLPAKNFGIIIV STPEGIMTHKEAKDRGIGGRLLAYVY--MHKARIKLTGTDPEKLAYVCDQLKKIAERTGVDMSGPIPLPTKRLVVPTRKS PDGEGTATWEKWEMRIHKRLVGI-EADERAMRQVMKVNVPDNVSIEIELGQILEGTVVSDKAERTVTVERSFYKFIRKYE RYEKRKSKIKAHKPDC-IDVRVGDTVKIAECRPLSKTKNFVVVE--VKG-LARKEFRYRGYTLEELQEMPLDDVIKLFPS RQRRSL-KRGFLPRQKKVLEKIRKIKK---EGKTEGRPPVIRTHCRDMIVLPEMVGMTFGIHNGKEFVEVKIQP-EMIGC YFGEFAPTRKKVEHG----DPGMGATR----FSM-FVPLK-- >ARCH_Natronomonas_pharaonis_DSM_2160 Concatenation of 2 sequences -M---------GRR----------ILGQ----------------------------R--RGRGTSTF-RAPSHRYK---- ---ADLS-HS-DLVT---GEVVDIEHDPARSAPLADVQFD-DGDRRLVLAPEGVTVGDEIQIGV-S-AE-IAPGNTMPLA EIPEGVPVCNVERQPGDGGKFARASGVSATLLTH--DRNAAVVQLPSGEMRRLSPECRATIGVVAGGGRTEKPFVKAGNK -HHKMKSRGGKW-P-RVRGVAMNAVDHPFGGGGRQH----PGKPKSVSR----DTPPGRKVGD-IASKRTG-RGKGGQE- MPQPSRPRKGSMGFSPRSRAASEVPRFNSWPDGLQ---G-FAGYKAGMSHVVAINDEPNSPREGQEETVPVTVVETPPMR AVAVR----AYE----D--TPY--GKRPLTE------VWT---VPE----------EQSGDIALDEGALADVRVITHTVP GALSSVPKKEPDVMETRV-GGGSLSDRVDFAL-----DLVDDGG-EHTV-TD-V-FRAGEYTDVAGITKGKGTQGPVKRW GVQK-RKGKHARQGWRRR-IGNLG-P-WNPS-RVRSTVPQQGQTGYHQRTELNKRLIDLGDDDV-----------SPDGG FVNYGEVDGPYALVKGS-VPGPDKRLVRFR--MKATVRD-LDGDDA-GEVELPA-VF----ET-DY-RPDLIKRAVLAAQ ANRIQDTGTDEYAGL--------------RTPA---------ESPGSGRGMAHVPRQ--NGR---AREVP----QA---- VSGRPAHPPK-AEKDRGLDINTKERKLATRSAIAATANADRVEERGHEFDEETDL-P-LVVSDEF---EDL--------- --VKTQLVV--T---S--D---DQSLAARNLAGSD-V---------------ATADEVNVEDLAPGTQAGRLTLWTESAL AEVA----------------MSSEPDAGEFHEMREPTVEKVVVHMGVG----RGGEPLAQAEEILEEIVEQQPVRTTAQK TIQDFEVREGDPIGTKATLRGEDAEEFLETALPLA--------DIDR-KQFDETGNFSFGVEEHTEFPSQE-----YDPQ IGIYGLDVTVNLV-RPGYRVHKRDKVSRSIPSNHR-LTAEDAVTFLESNFDVEV----M-R--TEIEIPDEVTAT-M--- -D-H--L-EVTVEGPNGSVTRRL-WYP-D--ITVDVED-GA--VVI----E-T-DDDNAKTR-STVGTFESHVTNMFHGV TEGWEYSMEVFYSHFPMQVSVEG-GD--IVIENFLGEKAPRKTPV-R-G-DTSVEVD--G-E-ELTVSG-PSIEDVGQTA ADIEQLT------RVSDK---DTR-VFQDGVYITETPDRMEALNADVTQGLEKGSLITCADNTGARELKVTSISG-TKNR HPKAGLGDKITVSVTKGTPE-----------MRRQVLEAVVIRQRKPIRRPDGTRVKFEDNAAVIVD-ENED-PRGTELK GPIAREV--AERFGSIASTATIIVMS--------------KKRRQRGS-RTHGGGSHKNRRGAGHRGGRGNAGRD----- -KHEF-H--NHEPL----GK-SG--FKRVNLRELSDDGYVVDARDVVEVK---------VLG--AGT-VYN---E-LEI- VADAFSESAEQALEVADGEAMD--IDKPAYTRREYITGIPGSKVAQYKMG-NFEADPEDYEVQISLIVDEEVQIRHGSLE ASRLSANRRMLKELGEDGDYKMILRKFPHQVIRENKQATGAGADRVSDGMRQAFGKIVGTAARINK-GERVFTIWCHP-- EDADAAKDAFRRAYNKISPPCTIKVTVPMRRRREARTNYHQRLRLLKSGKPRLVARKSNNQTKAQLVVT---GPQGDETV ASATSA-DLEA-FGWE----APT-GNLPAAYLTGLLAGKR--AIEAG-LDEAVLDIGLNTATPGNKVFAVQEGVIDAGLE VPHNEDVFADWQRTRGAHIAEYAEQL---EDGLYSGDF--------DATELPDHFDEVRERVDET-AKAMLRERHMSHKH SKEIAREIKGKTAGEAVDYLEAVIDGDRSVPFKSHNTGVGHRNDIE---GWDAGRYPEKASEAFLDLLENGINN----A- DHQ--GFEGEEMVIEHVAAHKVGESPGQKPRAFGRASPWNTPQVDVELVLRTNVRVNAGDTVEVQRGD------FA-GES GEVVTVDLRAA--EIH--VEDVTQETADGE-------------------EVPRPLEASNVQ-VTELDL------------ ----------------------EDEVR---EARLES---EED--MAD------------------------------E-H Q--FIHDGLQRTQIDEFF--SEELS-----RAGYGGMEVAKTP-M-GTQIVLKAEKPGMVIGKGGKNIRKITTTLEEEPQ VDVQEVDE---PDLNAQIVADRLANALERGWYFRKAGHTTIDRIMES-GALGAEIILSGKVTGA-RSRVEKFNRGYIKHN GEPAESIVDSGVGTAVMKLGTIGVQVKIIMADNDPLASALSGLDNAESVGHLEQTIQPASNEIGSVLEVFYDRGYVDGFQ FVD----D---G----KAGRFEVELKGA---INE-------C---GAVKPRY---SAGADEFEKWEKRFLPARDYGTLIV TTSHGVMSHYEAREQGIGGQVIAYVY--MQQARVRLAGTAPEDLDDICDDVREIADKTGVTLSGPVPLPTKTLEIPARKS PDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQVPNDVSIEIVLGQVIEGTVVSTDMERTVIVEREYDVNVPKYD RLMKRRSRIPAHVPEVLEPLSVDDEVKIAETRPLSKTKSHVVVEVTEGDIGHEGEFTYRGHTLDELQEMELDEVAELLPA RQRRTI-KRGLSVEQEKLLDEAREAGE---EETAN---NPIRTHLRDMPILPRFVGLTFAVYNGQSFERVEVEP-EMIGH YLGEFQLTRTSVEHG----QAGIGATR----SSK-FVPLK-- >ARCH_Nitrosopumilus_maritimus_SCM1 Concatenation of 2 sequences MGKRP-------------------LVRR-----------------------RGRGGNQFRSTSTGKV----GTKAN---- YPRFPLS-------EQHEGEIIDLVHERGREAPLAKVRFE-DGSVSFVPAVLGAKVGETLQFGL-K-SK-IEKGNVISIQ NIPDGTIVCNIEKHFGDGGAIVKSAGTDATVFSHGDEG--VTVKLPSGKFTTLNPKNRAMIGTLAGGGASERPFMSAGG- -KWRNFKAKGKKYP-IVRGVAQAAYVHPHGGGRHQH----VGQSSTVSR----DTPPGAKVGS-IAARKTG-R-ARIKER ARKRHSPRRGSLAYSPRVRAKSMEARIRAWPKKIL---A-HCGFKAGCVQIVSIDDREKVPNAGKQLVSLGTVLVTPPVL ILGIR--GYSKD----H--DGL--HAEFDVY------AED--ILDN----------AEKSLKK--------EIFAIVAIS PSAAGLEQKKPYIFEASV-----SGGDIPKQFAHVKELL---GK-EIKI--DQI-FETGASVDVAAITKGKGWQGVLKRW NVKK---KQHKSRKTVRE-VGSLG-P-ISPQ-SVMYTVPRAGQFGFHQRVEYDKRIMIMGNTDD-----D-KLKINPDGG FKHFGLVKGDFIVLKGS-VPGAYRRLIKLR-MTKTAVYT-TTGTKD-GEVELPA-VF----ST-PF-RRELIHKAFTNLT SHKFQPQGRHPTAGQ-------DVV-ADSNDPPTGQGVSR-ARAQGGGGGR--------QGQ---GAEVA----ST---- RGGRQAHPPI-VEKVIYKKLNKKEKKLALCSAIAATASKDRVESRGHKVEGIESF-P-IVVSDDI---ESV--------- --SKTSLFV--TKDAS------NISKAIGALPGVE-A---------------TSVKDLSVLDLAPGSDPIRLTVYSKSAI EEIG-------MSQT-------------TESPMKKISLEKVVLNMGVG----KSGDVIEIASRALEQISGKKPSARNAKE TQRDWGVRKGEPIGVAVTIRGDDAKALLKRLLEAKGNTVNG-------RAFDNFGNYSFGIREHIDIPGVK-----YEPS IGILGLGISVTLT-RPGYGIRTRSKHKASVGKSHI-ITSQEAKDYLVKEFGVTVTSQLE-KMQDQVEIPEGVTVT----- -Q-N-KN-MLLFEGPLGKTHKNF-RNI-P--VKIEIAD-GK--VNL----K-T-IGERKRDY-AILHTARSIIRNICEGL VEGYTIKMKVVFAHFPITVKVEG-KK--ILIENFQGERAPRSTHI-M---GNTKVIP--KGE-DVLLTG-EVWTDITQTA ANIELTT------KVKNK---DHR-VFLDGIYVYEKKKGVEEFRPYVTKVIPVGANIVCADNSGAKILEVINVPT-RASR LPSASVGDFCNVVVKKGPAE-----------LRKQVYGAVIIRQKYPVRRLNGVRVCFEDNAAVLIT-PEGE-TKGTDIK GPVAAEA--SEKWPRVANLASMVVTR-L--R---------KTRRLRGG-RHMGWGQVGQHRASGHKGGLGVTGMMKH--- -HWST-T-------LKDEPDHYG--HDSRDLDDLEGGKKVVDL-----EK---------LLG--GGK-V-S-N-A-YSV- KVTQYTASAEEKLKAVGGEV-E--GNGQVFTRRKYIKGKPQIKIAKFQGG-----KRGTYQYCVQLCINEKMQLRHMAIE STRLAANKTLEKTTG-ESGYYSRLRIYPHNMLRENKQIATAGADRISEGMRRAWGKATSLGARVRE-GQCIMELYVNG-D AHLAAAKKSLKSACVKLPGTPTI-KSKILRRLREEKTNYRKRSTMLMGKRDFITVNITNENTQVQILKP---GMTGDKVV ASAHSR-YLLE-KGWK----GSR-KSVPAAYLTGYLAGKK--ALGQG-AKDAILYTGTKRYT--QRMAAALKGVIDAGLE VPANEETFPSEERINGEHLT------------------------------VKNEVSKMKSTITRH-VRSSVREKDMSHKH AREVAVAIKGLSIEKARDYLQAVVNKDRAVAFRRYKNQVGHKADP----GMMSGRYPQKTAREFIKVLDNLESN----A- EYK--GMDLDRLKIVNATVHKGVIVKRFIPRAMGRATPKNNVLTHVELVAQESVRVNEGDSVTILRGE------FK-GVD GKVAEVSTAKS--SVA--IEGVKKEKTKGD-------------------KFDVFIHTSNLL-VTSLNT-----------E --DKWRIAK---LE---------GEPKEEKVEKKSE---EKE--MSSVKN---------VI-K----------------D N--YNMML-----LKDYL--RDAIK-----EAGFSHAEISKTP-T-GTRVALHVTRPGIVIGRKGSGIRDLTDKLATDPQ ISVVEIEK---PELSPSVMCNRMASHLERGTAFRRATMWTLKQIMEN-GAMGVQITISGKLRG-DRSAFEKHTAGILPRA GHHAEVIVAEDIAHVGTAMGLIGIRIRIAMPATNILANLFVTLYNNETRRKGECTILPTSKLGIEVLKTLQKDGYIGEFE HID----D---K----RGGKFKIKLLAK---ITK-------C---GAISPRFKVKTDE---FNNWEQQYLPAYDRGMLLV TTNQGVMSHHEATQKGIGGFLIGYVY-MTQTARVKLTSTSLPKLDGVCGEIMGIGKKTGVKVKGPTPLPVKRLHVATRKS PCGNGTETYEKWEMKMHRRIINI-NADDKAIRQLMRLKIPDDVYIELSLGKLFDGKVTGSKAKQTITLQKDAPVYFNKFK RYARGKSSIHAHVPGC-IDVESGDNVLTAECRPISKSVSYVVVE--VRS--MVKEFAYRGIPKEELDNMSLEKLFQLFNA RQRRSL-TRGITDGKRKLIEEIKAAKA---GKLKN----PIKTHVRDLIILPYMVDVTVNVFSGKEFRPVTIRT-EMIGH YLGEYVITNRKVSHG----APGVGASR----SSL-YVPLK-- >ARCH_Picrophilus_torridus_DSM_9790 Concatenation of 2 sequences MGKHI-------------------VAQR-------------------------------RGHGSLVY-RSPSHRHL---- -GDIKYP-R-----DGT-YKIEDIIQAPGRNTPVLLIRNE-KNEKNYMIAFNGAYVNQEIHVGD---IDSPAIGDVTYLA NIPDGSYVYNIESIPGDGGKFCRAAGTAALVISH---GAYVSLKLPSGVNKEFHPRCRATVGFIAGSGARDIPILKAGTH IKYL--QSKAKR-PYTVRGVAMNAVNHPHGGGNHQH----VGRPSTVGR----GTPPGRKVGR-LSPK----R----RKK MATPHHSRRGSMAYYPRVRAKRIQGDIRSWPEGQTKVQA-FAGYKVGMTHIQMVDYRKNSVTAGQVIMAPVTVVEVPPLT VMSIR--YYARG----D--NGL--EVISEEW------AENIDKINR----------HKKGIEK----DVDDVRLMVHTNP QLVSGVPSKTPEIFEIRI-----GGSTIENRIKYAKERL---GS-NISF--SDF-SKPGNFVDVIAVTKGKGFQGVVKRF GVKL-LPRKN---RKHRRMIGTLGP--WHPD-WVRNTVPQAGQVGFHQRTIHNIRIIKFDTKDH-------VDDINVKGG FLNYGIVRNDYVLLFGS-VPGPAKRLIKMR--MKANIYD-LNGEIK-GEIELPK-IF----EI-RP-REDILREAFRAIT LSYRQPYGASPDAGM--------RRVGQNLGP-------------NHGISRIPRL----AGG---SR-AV----LL-GSV VGGKSAHAPR-SDKVLYKKINKRERKLARFTAIALTASREHIIKRGHRIDEDSNLTP-VIVTNDL---EKI--------- --KKTRLIV---GTS---Y---DNLKAFSSLPGVD-I---------------ATPSSLSIRKLAPGGTGGRLTIFTESAI SSLK-------MMET-------------TENSMREIVIDKVVVNIGVG----AAGERLNRAAKVLELLTHHKPAFTSAKR TVRDFNIRKGLNIGVKVTLRKDDALSFLKEAFYA-----KDYK-IPV-YSFDKNGNAYFGISDYTDFKGMK-----YDPD IGIFGMDIAIVFRRRGGYRIEKRRIKKMHIPKKMR-ISKEETIKYLQENFNVKI-MIKW-TEQAEIKLPDDVQAT-M--- -E-N--N-ELKIKGKLGEASRIF-RDN-Y--VKAYIEG-SS--VKI----A-T--SKNKYTK-GIVGTWYSETKLLIEGV TKGFEYHMKIDFTHFPMRVSVRG-DK--LIVENFLGEKSPRSAKI-V-D-GCKVSVK--G-D-RITING-IDKRKIGETA ANIERAT------YIRHF---DAR-VFQDGIFLLKGEVNMKGISGRETRGLPLGALIPCVDNTGAKMISLIDVKT-VAKR IPAAGVGDMFIASVKKGTPE-----------MRSKVVYAVVVRQRRPYRRADGTMIEFEDNAAVLVT-PDGE-VRGSEIK GPVAREA--AERWPRIAAISSTIV-------MVRT-----RTKKLRGG--HYGRGM-KAGRGKGKKGGNGMAGLGKHRWV WLLKY-D-RDHFGV-------HG--FKSITLEELLKENGFVHD-DVIDTK---------LLG--TGD-F-D-I-K-SRI- KIERATEKAINKLSVHGITIMR--ITGPAYTRKEFMGGVPYPKITTFIQG----NQKKDFEIEMMLVAEEACQIRHTALE AARVSVNRKLLDAAG-SDNYFLQIRPYPHQVIREHKMATGAGADRISSGMRAAFGRPVGTAARVYP-GQIIMVGRVDR-- NNAKLLKDALHKASIKLPTPCKV-VPPVLKRRREGVTDYRKRYRLVISRETRAVIRQTRKGLIIQLVDY---VPEGDHVL VTVTNK-TLKK--ALN----IDG-NNIQMYYLAGYMAAKK--GISLG-ISGAVVDTGRAIFRKGGRIAAAIKGLIDGGLE INADEDIFPDESRLNGEHLKQ------------------------------RLDINEIKSKIERS-ARARIREIDISLKD AVNVAHFLKGMDLDSAKNVLDNVIEKKVPVPYFRYMDSVSHRK------GIGPGRYPVKAARAFKKLLEDVSAN----A- EFK--GLS-DSLEIVHIAVSKGRMIKKYTPKAYGRAGAFFKDLVNLEVVVRERFPVAKGDIVKIISGS------RK-GEG GKVVDVDHKTM--KVS--IEGVTISKADGK-------------------QVPFFIDHSNIS-ITKLDL-------SR--N --DRYERLR--EIAANPPPEVPEETSN---DTKESD---ENV--MKEK--------------R----------------- ---FVNDNIKRLLVSEYL--RKEND-----NAGFGGMEMKRTP-Y-GTNITLYVNRPGLVIGRHGTKIKEMTETLEKRPQ IEVKEVNT---PDLNPQIASKKIALSLEKGWNYRKAGNTSLRKMIDL-NAPGVLIRIGGKISG-ERARAQKFMFGKIKYS GEPARSGVEYGFSEAKLKTGIIGVSVRIL-MNHDPLNDVINTIKNASRIGKSEVIIGPASVMIGRILKVMQDYNYIKSFE VIE----E---E----RGGKFRVELSDT---INN-------C---GVIKPRLSVKNSNIERYESR---YLPAQDFGIIIL TTTKGIMSHIEARKLGIGGKLLAYVY-MVYKARISLSGTENKIVDVVCEEIKGIAKRTGVEIHGPIPLPTKRLVVPVRKS PDGEGSPTWDRWEMRVHKRLIDV-DADERTLRQLMRISIPDGVRIEIQIGQIIVGTVVSTKMNGSIVLKRESRRLIKKYE RYETKISKFHAHLPGC-IDVRPGDRVKIAECRKLAKTISFVVVE---KVTGRAKEFSYRGHSLEELQNMELNELLPLLPA RARRSY-SRQMNHEQEKLYEKL--------LGDKE----NIKTHVRDLIVLPQFVGKTIELYNGNSYIKFEIKP-EMIGH YLGEFALTRKEVKHS----GPGVGATR----SSK-FLPLK-- >ARCH_Pyrobaculum_aerophilum_IM2 Concatenation of 2 sequences MGKRI-------------------LVQR-------------------------------RGRGGSQF-RSPSWKRDGPVR YPPLGVI-S--GK-----GYVVDILHEPGLNAPVAKIVTE-NGVEFFNYAAEGLYVGQVVEIGK-G-AS-PKTGNIMILG EIPEGTMIFNVEKRAGDGGKFARAGGTYAVVIGQKPEENKTIIRLPSGRTVEVDSRGRATVGIVAGGGRIEKPFLKAGKK -YHRARAKAWKY-P-TVRGKAMSPYAHPHGGGSHQK----GGTPVPKTA------PPGQKVGF-IGSRCTG-R-GCVRAR GLKINRPRRGSMGVYPRKRAADIVPRVRTWPEGKPALLG-FAAYKAGMLHAVVVDDRPTSPLYGKEVVKAVTVLDAPPLY VWGFRLYTLDPT-------NGYKRAVAEVWA-------SE--LLHR--VLTLPEKLDVDKQLVEEFRDVAVDVRALVATQ PHLSGIGKKTPELLEIPI--GGVPSVDERINF-----AISLLGK-TVSP--KDV-FTPGQLVDVIAVTKGKGYQGVIKRF GVTI-LPRWHKHRKGHRR-TGTIGP--QAPA--VMFTQPRPGQMGFHQRTEYNKRLLKIGENGA---------EITPKSG FPHYGVVKGPYILIQGS-VPGARKRLVVLRPAEKLKVYG-IDGAYV-ADIEAPLHFL-------EPIRPDLIRRAYLSAL SARFQPKGVYEGAGKEHSCESFGVGLGIARIP----------RYKGSLWPR---------GC---F--AP----NT---- RGGRRAHPPK-VEKKLHEEINKKEKKLAIRSAIAATAYRSWVAARGHVVEKVPSL-P-VVVVGDA---EKI--------- --NRAKLVV--VSDLN--A---PLIAAVRNFPGVD-V---------------VAVNNLNILVLAPGGVPGRLTLWTAPAV EKLRPSWKELV---------------LVKGHPMQRIYIEKVVVNIGVG----ASGEKLEKAAGLLKELTGAEPSRRRAKK SIKDFGIRKGEPIGVAVTLRRDQAVNFLMRALQAVNNRVKK-------TSFDDRGNVCFGIKEHILLPGVK-----YDPA VGIWGMDVCVKLA-KPGLRVQLRRRRRSKVGKRQL-VTKEEAIEFFQKVLGVQVM-RVV-YSVEEVEIPKGVSVS-IERT GPFD--Y-IVKVKGPLGEVTKEF-KNT-P--VVMSLQD-GK--IVM----E-V--FKAKREY-AILGTYKGILKNMFLGV TRGWRYKLKVIYTHFPMLVKVQG-NQ--LVIENFLGRKSKITLNI-P-K-GVKVEVK--GKE-DIVIEG-IDRELVSTFA AAVQAATELHGDERPSPHGREGGLGV-VDGIYVVGYEHIGVPYRFHVTPGIFMNSLVPVADNSGAKLVRVIGVVT-VHRR IPGAGVGDMVVVVVREGKPE-----------LRKQIFRAIVVRQRRPYRRPDGTWVAFEDNAVVIVT-PEGD-PKGSEIH GPVAMEA--TLRWPTIANLASIVV-------MVRRFK---RGTKYRRGSRTHGWGRVGQHRKSGGSGGKGMVGFHKHKWS LVMKYGESGTGWPFYGK----HG--FKQINVGTLKAEGKVREE-GGKYNK---------LLG--GGT-I-D-L-P-VIV- YTPIASRTAVEKIEKAGGEVMR--IKGPPYTREEYIHGAPMIQIPKFDMGTTSAAARTAFTMTAKLVVEERGQIRMQALE AARQMASKYLTKYVG-DANYYLRLNVVPHHVLRENRMLAMAGADRLQEGMRLAFGSPAGRAARVEP-GQVLFYAEFKP-- EHLPHIKEALRRAASKLPLPTRI-VKVPFRRRREGLTNYRKRRKLLLSKKPRLVVRKTNKHIIAQIVVA---KPQGDVTI VGADTR-ILAK-FGWR----GDE-NNVAAAYLLGLVVGYK--ARARR-VEEAILDIGLHRPAPGARVFAVLKGALDAGLK IPHGEEVLPDEDRIKGKHVAEYAEKLKEENPEAYKARFSRYLQRGLEPEKLPEHFEEVKKKIEQI-ARAYAPEQRMSWKK SVEVARFIKGMTLKQAKTWLEDVVKLKRPVPIKTFKKKQAHHATPWE--GWPVAKWPVKVARRFLQVLENLENN----A- RFR--GLDVDRVVIVHAAAHKGFKIPNIMPRAFGRATRFDEQTVNVELVAVERLPVRRGDTVLILRGD------FK-GVT GKVVKVDLKRV--RIY--VEGATRTNSRGQ-------------------TVYYPIHPSKVM-IVDVDL-----------S --DKARQKI---IE--------RRKKK-----------------M----------------------------------- -------------IKEFL--EYRLS-----KYGYIDSEILKTP-L-GTRIVIYAERPSRIIGRKGAIVKEISNILTTKPQ IDVIDISKIEAPEMFPKVVAYRIANAMAKGVRFRRVMFVAIRQLMEA-GAKGFEIVVSGKLS-TERARFEKQTYGKLYKI GYDAKNRVRRAVVHVLLKPGIYGIEVRIAMVMLDILSNALIQIKNAEIVGKKQAVIWPVNKLTYYTLRVLQRYGYVGEIE YID----D---G----KGGKYIVQLLGK---IND-------I---GPIRPRYPVK---YREIVQWEQKFLPARQIGILII STSQGVMSHIEAKERKIGGVLLAYVYASRRKVRIRLYGTNPADVEQVAREIVDLAKKMGVQVRGPIPLPTRRLIVTVRRA PSGQGYHTFDHWEMRISKRLIDI-EASERVLRRLMTIRVPDTVKIELQLLKLLEVTVEKVRMHKAAVVIHEWLHYIRKYN RYERRRKRMRVRVPEC-IEVKPGDKVIIAETRPLSKTIAWVVIGKKEDVPEEWATFRYRGKTLEELLNMSMDEFIKLLPA RQRRSL-KRGLKPEHRKLLEKIRKAKRLAAQGKKV----VIRTHCRDMIILPEMVGLTIHVYNGITYIPVFISP-WHIGH YLGEFALTTKIVQHG----EPGLKATR----SSL-HIAAK-- >ARCH_Pyrobaculum_arsenaticum_DSM_13514 Concatenation of 2 sequences MGKRI-------------------LVQR-------------------------------RGRGGSQF-RSPSWKRDGPVR YLPLEATGR---------GYVVELLHEPGLNAPVARIVTE-SGAEFFNYAAEGLYVGQVIEMGS-G-AT-PKAGNIMILG EIPEGTMIFNVEKRAGDGGKYARSSGTYAVVVGQKPEENKTIIRLPSGRVIEVDARGRATVGIVAGGGRIEKPFLKAGKK -YHRARAKAWKY-P-TVRGKAMSPYAHPHGGGSHQK----GGTPVPKTA------PPGQKVGF-IGSRCTG-R-GCVRAR GLKINRPRRGSMGVYPRKRAADIVPRVRTWPDALL---G-FAAYKAGMLHAVVVDDRPTSPLYGKEVVKAVTVLDAPPLF VWGFR--LYTLD---PT--NGYLRSAAEVWA-------GE--LLSR------VLTLPEKVDVVEEYRDVAVEVRALVATQ PHLSGIGKKTPELLEIPIGGVPNIDERIKFAI-----SLL--GK-TVSP-KD-V-FSPGQLVDVIAVTKGKGWQGVVKRF GVTI-LPRWHKHRKGHRR-TGTIGP--QAPA--LMFTQPRPGQMGFHQRTEYNKRLLKIGENGA---------EITPKSG FPHYGVIKGPYILIQGS-LPGARKRLVVLRPPEKLKVYG-PDGAYI-AEIDAPPHFF-------EPVRPDLIRRAYLSAL SARFQPKGVYEGAGKEHSCESFGVGLGIARIP----------RYKGSLWPR---------GC----F-SP----NT---- RGGRRAHPPR-VEKKLHEEINKKEKNLAIRSAIAATAYRTWVATRGHVIDKVQSL-P-VVVSGDA---EKI--------- --AKAKLVV--VSAAD--A---PLAAAVRNFPGVD-V---------------VPAEHLNMLVLAPGAVPGRLTLWTAPAV EKLRPSWKELV---------------LVKQHPMQRIFIEKVVVNIGVG----TGGERLEKAAELLKELTGAEPSRRRAKR SIKDFGIRKGEPIGVMVTLRRDQAVNFLMRALQAVNNRVKR-------TSFDDRGNVCFGIKEHILLPGVK-----YDPA VGIWGMDVCVKLA-KPGLRVQLRRRRRSKVGKKQL-VTREEAVEFFQKVLGVQVRVVYS-V--EEVEIPKGVNVS-IEKT GPFD--Y-VVKVKGPLGELVKEF-RNT-P--VVMNVQD-GK--ILL----E-V--FNVKKEY-AILGTYKGILKNMFLGV TKGWRYKLKIIYTHFPVLAKVQG-SQ--LVIENFLGRKSKITLDIPK---GVKVEVK--GKE-DIVVEG-IDRELVGTFA SSIQAATELHGDERPSPHGREGTLGV-VDGIYVVGVEHIGVPYRFHVTPGIFMNSLVPVADNSGAKLVRVIGVVT-VHRR IPGAGVGDMVVVVVKEGKPE-----------LRRQIFRGIVVRQRRPYRRPDGTWVAFEDNAVVIVT-PEGD-PKGSEIH GPVAMEA--TLRWPTIANLASIVV-------MVRRFK---RAVKYRRGSRTHGWGRVGQHRKSGGSGGKGMVGFHKHKWS LVMKYGESGTGWPFYGK----HG--FKQINVGTLKSEGKIREE-GGKYNK---------LLG--GGS-I-D-V-P-VIV- YTPVASKTAVEKIQRAGGEVMR--IKGPPYTREEYIHGAPMIQIPKFDMGTTSAAARATFPMVAKLIVEERGQIRMQALE AARQMASKYLTKYVG-DANYYLRLNVIPHHVLRENRMLAMAGADRLQEGMRLAFGSPAGRAARVEP-GQILFYAEFKP-- EHLAHIKEAFRRAASKLPLPTRI-VKVPFRRRREGLTNYRKRRKLVISKKPRLVVRKTNKHIIAQIVVA---KPIGDETV AGADTR-ILTK-FGWR----GDE-NNTSAAYLLGLVVGYK--ARMRG-VEEAILDIGLHRPTPGARVFAVLKGALDAGLK IPHGEEVLPSDERIRGEHIAEYAAKLKEENPDAYKARFSRYLQRGLEPERLPDHFEEVRKAIEQI-AKAYAPEQRMSWKK SIEVARFITGMTLKQAKAWLEDVVKLKRPIPIKTYKKKQAHHAAPWR--GWPVAKWPVKVARRYLQLLENLENN----A- KFK--GLDADRVVIVYAAAHKGYRIPNIMPRAFGRATRFDEQTVNVEIVAAERLPVRRGDTVMILRGD------FK-GVT GKVVRVDLKKV--RIY--VEGATRTNSRGQ-------------------TVYYPIHPSKVM-IVDVDM-----------S --DKARQKI---------------------IERRKK--------MAMSVQQRRLPVYKKIL-EENKKKWMI--------- --------------KEFL--EYRLS-----KYGYIDSEILKTP-L-GTRIVIYAERPSRIIGRKGAIVKEVSNILATKPQ IDVIDVSKIEAPEMFPKVVAYRIANAMAKGVRFRRVMFAAIRQLTEA-GAKGFEIVVSGKLS-TERARFEKQTFGKLYKI GYDAKNRVRRAVVHVLLKPGIYGIEVRIAMVMLDILSNALIQIKNAEVMGKRQVTIWPVNKLTYYTLRVLQRYGYVGEIE YVD----D---G----RGGKYIVQLLGK---IND-------I---GPIRPRYPVK---YREIVQWEQKFLPARQIGILVI STSQGVVSHIEAKEKKIGGVLLAYVYAARRKVRIRLYGTNPADVDQVAREIVDLAKKMGVQVRGPIPLPTRRLVVTVRRA PSGQGYHTYDHWEMRISKRLIDI-EASERVLRRLMTIRVPDTVKIELQLLKLLEVTVEKTRMRKAAVVVHEWLHYIRKYN RYERRRRKLHVRVPEC-IEVKPGDKVIIAETRPLSKTISWVVIGKKEDVPEEWATFRYRGKTLEELLNMPMDEFIKLLPA RQRRSL-KRGLKPEHRKLLEKIRKAKRLAAQGKKV----VIKTHCRDMIILPEMVGLTIQVYNGITYIPVYISP-WHIGH YLGEFALTTKIVQHG----EPGLKATR----SSL-HIAAK-- >ARCH_Pyrobaculum_calidifontis_JCM_11548 Concatenation of 2 sequences MGKRI-------------------LVQR-------------------------------RGRGGSQF-RSPSWKRD---- -GPVRYP----PN-ISGRGIVVEILHEPGLNAPVAKIRME-NGVEFFNYAAEGLYVGQVIQVGP-D-AP-PAVGNVLPLG KIPEGTMVFNVEKRFGDGGKFARSGGTYALVIGQRPEENKTIVRLPSGRVIEVDARGRATIGIVAGGGRVEKPFVKAGKK -YHRARAKSWKY-P-TVRGKAMSPYAHPHGGGSHQK----GGTPVPKTA------PPGQKVGF-IGSRCTG-R-GCVRAR GLKINRPRRGSMGVYPRKRAADIVPRVRTWPETLL---G-FAAYKAGMLHAVVVDDRPTSPLYGKEVVKAVTVLDAPPLY VAAVR--LYTLD---PT--NGY-----KVAV-------GEAWVTEK----------QLKALER----DVAVDVRVLVATQ PRLSGIGKKTPEVLEIPVGGVPSIDERINFAI-----SLL--GK-TVSP-KD-V-FTPGQLVDVIAVTKGKGYQGVVKRF GVTI-LPRWHKHRKGHRR-TGTIGP--QAPA--LMFTQPRPGQMGFHQRTEYNKRILKIGDNGA---------EITPKSG FPHYGVIKGPYILLQGS-VPGARKRLVVLRPPEALKVYD-VNGQYM-ADIETPIHFY-------EPVRPDLIRRAYLSAL SARFQPKGVYEGAGKEHSCESFGVGLGIARIP----------RYKGHLWPR---------GC----F-AP----NT---- RGGRRAHPPR-PEKKLHEEINWKEKNLAIRSAIAATAYKSWVAARGHMVEKVPSL-P-LVVSGDA---EKI--------- --AKAKLVV--VSELD--V---PLIGAVRNFPGVD-V---------------VPVSHLNMLVLAPGGVPGRLTLWTATAV ERLKMKWKELV---------------LVKDHPMKRVYIEKVVVNIGVG----TGGERLEKAANLLRELTGAEPSLRRAKR SIKDFGIRKGEPIGVAVTLRRDKAVEFLMRALQAVGNRIKR-------SSFDERGNVCFGIKEHIMLPGVK-----YDPA VGIWGMDVCVRLA-KPGLRVQLRRRRRSKVGKGQL-VTREEAVEFFQKVLGVQVHVVYA-V--EEVPIPDGVKVA-IEKT GPFD--Y-VVKVKGPLGELVKEF-KNT-P--VIMSLSD-GK--VVL----E-V--LNAKREY-ALLGTYKGILKNMFLGV TKGWRYKLKVIYTHFPMLVKVQG-NQ--LTIENFLGRKSKIVLEI-P-K-GVKVEVK--GKE-DIVVEG-IDRELVSQFA AAIQAATELRGEEKPSPHGREGGLGV-VDGIYVVGYEHVGVPYRFHVTPGIFMNSLVPVADNSGAKLVRVIGVVS-VHRR IPGAGVGDMVVVVVREGKPE-----------LRKQIFRAIVVRQRRPYRRPDGTWVAFEDNAVVIVT-PEGD-PKGSEIH GPVAMEA--TLRWPTIANLASIVV-------MVRRFK---RATKYRRGSRTHGWGRVGQHRKSGGSGGKGMVGFHKHKWS LVMKYGESGTGWPFYGK----HG--FKQINVGRLRERGEVREEEGRLVNK---------LLG--GGH-M-D-V-P-LVV- YTPVASKAAVEKIAKAGGEVMR--IKGPPYTREEYIHGAPMIQIPKFDMGTTSAAARAAFTMVAKLVAEERGQIRMQALE AARQISSKYLTKYVG-DANYYLRLNVVPHHVLRENRMLAMAGADRLQEGMRLAFGSPAGRAARVEP-GQVIFYVEFKP-- EHLAHVKEALRRAASKLPIPTRI-VKVPFRRRREGVTNYRKRRKLLLSRKPRLVVRKTNKHLIAQIVIA---RPHGDETV VGLDTR-VLSK-FGWK----GDE-NNTSAAYLLGLIVGYK--ARAKG-IKEAILDIGLHRPTPGARVFAVMKGVIDAGVE VPHGEEVVPSEERIRGEHVAEYAKRLKEEAPEAYKARFSRYLQRGLPPEELPSHFEEVKKKIEQI-AKAYAPEQRMSWKK SVEVARFIKGMTLKQAKAWLEDVVKLKRPIPIKTFKKKQAHHATPWE--GWPVAKWPVKVAKRYLQLLENLENN----A- KFK--GLDVERLVIIHAAAHKGIKIPNIMPRAFGRATPFNEETVNVEIVAAERLPVRRGDTVLIMRGD------FK-GVT GKVVKVDLKRV--RIF--VEGATRTNSRGQ-------------------TVYYPIHPSKVM-IVDVDL-----------S --DKARQKL---IE----------RKR---GQHGSS--------MSVAMSTAQRRLP--VY-K--------------K-- ---ILEENKKKWMIKEFL--EYRLA-----KYGYIDSEILKTP-L-GTRIVIYAERPSRIIGRKGAIVKEVSSILANKPQ IDVIDVSKIEAPELFPKVVAYRIANAMARGVRFRRVMFVAVRQLMEA-GAKGFEIVVSGKLS-TERAKFEKITYGKLYKI GYDAKNRVRRAVVHVLLKPGIYGIEVRITMVMLDLLSNALTAIKNAEAMGKRQVVIWPVNKLIYYTLRVLQRYGYVGEIE YID----D---G----RGGKYVVQLLGK---IND-------I---GAIRPRFPVK---YREIVEWEQKYLPARQIGILVI STSQGVMSHLEAKEKKIGGVLLAYVYASRRKVRIRLYGTNPADLDQVAREIVDLAKKMGVAVRGPIPLPTKRLMVTVRRA PSGQGYHTFDHWELRISKRLIDI-EASERVLRRLMTIRVPDTVKIELQLLKLLEVTVEKVRMHKAAVVTHEWVHYLPKYN RYERRRRRMRVRVPEC-IEVKPGDKVIIAETRPLSKTIAWVVIGKKEDVPEEWGSFRYRGKTLEELLNMPMDEFIKLLPA RQRRSL-KRGLKPEHRKLLEKIRKAKRLMAQGKKV----TIKTHCRDMIILPEMVGLTIHVYNGITYIPVFISP-WHIGH YLGEFALTTRIVQHG----EPGLKATR----SSL-HIAAK-- >ARCH_Pyrobaculum_islandicum_DSM_4184 Concatenation of 2 sequences MGKRI-------------------LVQR-------------------------------RGRGGSQF-RSPSWKRDGPVR YPPLNVTGR---------GYVVEILHEPGLNAPVARIRLE-NGVEFLNFAAEGLYVGQEIEVGD-L-AA-PKTGNIVILG RVPEGTMVFNVEKRAGDGGKFARAGGTYAVVVGQKPEENKTIIRLPSGKVVEVDSRGRATVGIVAGGGRIEKPFLKAGKK -YHRAKAKAWKY-P-TVRGKAMSPYAHPHGGGSHPK----GGTPVPKTA------PPGQKVGF-YGSRCTG-R-GCVRAR GLKINRPRRGSMGVYPRKRAADIVPRVRTWPETLL---G-FAAYKAGMLHAVVVEDRPTSPLYGKEVVKAVTVLDAPPLF IWGFR--LYTLD---PT--NGY-KRSIAEVW-------AP-ELLRR------VLTLPEKVDVK----DVAVDVRALVATQ PHLSGIGKKTPELLEIPI--GGVPSVDERIKF-----AVSLLGK-TVSP--KEV-FTAGQLVDVIAVTKGKGYQGVIKRF GVTI-LPRWHKHRKGHRR-TGTIGP--QAPA--VMFTQPRPGQMGFHQRTEYNKRIIKIGDNGA---------EITPKSG FLHYGVVKGPYILIQGT-VPGARKRLVVLRPPEKLKVYG-RDGAYV-ADIDPPVHFM-------EPVRPDIIRRAYLSAL SARFQPKGVYEGAGKEHSCESFGVGLGIARIP----------RYKGSLWPR---------GC---F--AP----NT---- RGGRRAHPPR-VEKKLHEEINKKEKNFAIRSAIAATAYKSWVMARGHIIDKVPSL-P-LVVVSDV---ENI--------- --SKAKLVV--VSSSK--A---PLAFAVRNFPGVD-V---------------VSVDNLNMLVLAPGGVPGRLTLWTTTAI EKLRPNWRELV---------------LVKEHPMQRIFIEKVVVNIGVG----TGGEKLEKAASLLKELTGAEPSKRRAKR TIKDFGIKKGEPIGVAVTLRRDKAVEFLMRALQAINNRIKR-------SSFDNRGNVCFGIKEHILLPGVK-----YDPA VGIWGMDVCVKLA-KPGLRVQLRRRRRGKVGKRQL-VTREEAIEFFQKVLGVQVMHVVY-SV-EEVEIPQNVKVS-VEKI GPFD--Y-VVKVKGPLGEITKEF-RNT-P--VVMNLRD-GK--VVL----E-V--FNAKKEY-AILGAYKGILRNMFLGV TKGWRYKLKVIYTHFPMLVKVQG-NQ--LIIENFLGRKSKIVLTI-P-S-GVKVEVK--GKE-DIIVEG-VDKDLVSQFA ATIQSAVELRGDERPSPHGREGGLGI-VDGIYVVGYEHIGVSYRFHVTPGIFLNSLVPVADNSGARLVRVIGVVT-VHRR IPGAGVGDMVVVVVREGKPE-----------LRKQIFRAIVVRQRRPYRRPDGTWVAFEDNAVVIVT-PEGD-PKGSEIH GPVAMEA--TLRWPTIANLASIIV-M-V--RRFKPAV------KYRRGSRTHGWGRVGQHRKSGSSGGKGMVGFHKHKWS LVMKYGESGTGWPFYGK----HG--FKQINVGSLKKEGKIAEE-GGKYNK---------LLG--GGH-I-D-V-P-VIV- YTPAASRTAVEKIEKAGGEVMR--IKGPPYTREEYIHGAPMIQIPKFDMGVTSAAARAAFSMVAKLVVEERGQIRMQALE AARQMAYKYLSKYVG-DANYYLRLNVVPHHVLRENRMLAMAGADRLQEGMRLAFGSPAGRAARVEP-GQVIFYAEFRP-- EHIAHIKEALRRAASKLPLPTRI-VKVPFRRRREGLTNYRKRRKLLLSKKPRLVVRKTNKHIIAQVVVA---KPQGDVTI VGIDTR-ALAK-FGWK----GDE-NNTPAAYLLGLIVGYK--ARIRG-VKEAVLDIGLHRPVAGSRVFAVLKGALDAGLE IPHGEEIIPSDDRISGKHIAEYAEKLKKENPELYKTRFSRYLQRGLAPEELPTHFEEVKKKIEQI-VRAYAPEQKMSWKK SVEVARFIKGMTLRQAKSWLEDVVKMKRPIPIKTFKKKQAHHAVPWS--GWPVAKWPVKVAKRFLDLLENLENN----A- KFR--GLDVERVVIVHAAAHKGYRIPNIMPRAFGRATRFDEQTVNVEVIAAERLPVRRGDTVMIMRGD------FK-GVT GKVVKVDLKKV--RIY--VEGATRTNSKGQ-------------------TVYYPIHPSKVM-IIDIDT-----------S --DKIRQKI---------------------IQRRKK---E----M----SAVQRRLP--VY-K--------------K-- ---ILEENKKKWMIKEFL--EYKLS-----KYGYIDSEILKTP-L-GTRIVIYAERPSRIIGKKGVIVKEISNILVNKPQ IDVIDVSKIEAPEMFPKVIAYRIANAMAKGVRFRRVMFVAVRQLMEA-GAKGFEIVVSGKLS-TERARFEKLTYGKLYKI GYDAKNRVRRAVVHVLLKPGIYGIEVRIAMVMLDLLSNALIQIKNAEIMGKKQVVIWPVNKLIYHTLRVLQRYGYVGEIE YID----D---G----RGGKYVVQLLGK---IND-------I---GPIRPRYPVK---YREIVQWEQKFLPARQIGILVI STSQGVMSHIEAKERKIGGVLLAYVYAARRKVRIRLYGTNPADVEQVAREIVDLAKKMGVQVKGPIPLPTRRLVVTVRRA PSGQGYHTFDHWELRISKRLIDI-EASERVLRRLMTIRVPDTVKIELQLLKLLEVTVEKVRMHKAAVVLHEWVHYIRKYN RYERRRRRIHVRVPEC-IEVKPGDKVIIAETRPLAKTISWVVIGKKEDVPEEWSTFRYRGKTLEELLNMPMDEFIKLLPA RQRRSL-KRGLKPEHRKLLEKIRKAKKLMAQGKKV----VIKTHCRDMIILPEMVGLTIHVYNGITYIPVFISP-WHIGH YLGEFAITTKIVQHG----EPGLKATR----SSL-HIAAK-- >ARCH_Pyrococcus_abyssi_GE5 Concatenation of 2 sequences M------------------------------------------GKSLIQQR--------RGKGSPTF-RSPSHRFRGAVK YIPLNYT-Q--DK--TLRGVVEEIMHDPGRTAPVARVRFE-NGMEKLIIAPEGLLVGQEIYIGP-D-AP-IAIGNTLPLA KIPEGTYVYNIEGIPGDGGKYVRAGGTYALVVSR--EKDKVIVQLPSGELKAFNPNCRATIGVVAGGGRLEKPLVKAGKA -YYKYKARNRFW-P-TPRGVKMNAVNHPFGGKEHH-----PGKPTTTSR----RAPPGRKVGH-IAARRTG-------RR MGKVHRPRRGSLAFSPRKRAKSIVPRIRSWPKRML---G-FAGYKAGMTHILMIDDEP-GLTNGKEIFMPVTIIETPPLR VFGIR----AYR-------QGY--LGLETAT-------EV--IATLPKNYTKDDFEQKLGNLDMIKEGEIVEVRALVATQ PWVIK-LKKKPEVMEYAI-----GGTSVEEKFNYIKEKL---GK-ELRV-GE-V-LKEGELLDVIAVTKGKGTQGPVKRW GIKL---RAHKDSKGRRK-VGSIGP--WHPA-RVMWTVPMAGQMGFHHRTELNKRLIAIGENGK-LVIDGNEIEITPKGG FPHYGIVRSDFMMIAGS-VPGAIKRIIRVR--MKVKVFD-LNGQPV-DEIELPKVFF-----T-PF-RPDLIRRAVIASW THRIQPQGRDPMAGK-----------RRVTENI----------GKGHGMAR--------VER---LK-TPPRYAAFVPFA RGGRRTHPPK-VEKIIWEGINKKERRLAIMSAIAATANYDIVKARGHIIDNVPQL-P-LIVVDDL---QKV--------- --SKTRLIV--VGKN---E---GIVFGARNHPGVD-V---------------VVVDNLGVEHLAPGTHPGRLTVWTVSAI ERLKMAITIPN--------REEILADWE-AHPMRKPRIEKVTINIGVG----ESGERLTKAEIMLERLTGQKPIRRKAKK TNRDFGIRRGEPIAVKVTLRGPKAYEMLKRLLAAVDNRLKA-------SSFDEHGNVCFGIDEHINIPGVE-----YDPE IGIFGMDVCVTLE-RPGFRVARRKRKRAKIPTRHK-LTKEEGMVYMMEEFGVEIVDAWV-R--EEIEIPEGVEVS-V--- -Q-G--N-TVKVKGPKGEVEREL-FWP-G--VKIFVEG-GK--VVI----Y-K-DFPRRKDV-AIVRTFKAHINNMIKGV TEGFTYKLKVVYSHFPITVKVQG-DE--VIIENFLGEKAPRRAKI-L-P-GVTVKVK--G-Q-EIIVEG-IDKEAVGQTA ANIEQAT------RITKW---DRR-VFQDGIYIVEKAGKRGITPVRPTRAIPVGAYLTVADNSGAKVIQVIGVVG-TRRR LASAGVGDMVVATVKKGRPD-----------MRHQVVRAVIIRQRKEYRRLDGMRIKFEDNAAVIVT-PEGV-PRGTEIR GPVAREA--AERWVRIGSIASIIV-------MIRRRK---KVRKLRGS-HTHGWGCKKKHRGGGSKGGRGMAGTGKRNKS KWTWT-I--KYAPD--HLGK-RG--FSRVTLKSILQKGIAYEEEGKIIDK---------VLG--TGK-I-T-K-P-LVI- KARAFSSKAEEKIKAAGGEAMY--VDKPAYTRREYIRGAPGPKITIFDMG----NPAGDFEFEVALHVSQPVQIRQNALE AARQQVNRYLQKNVG-RSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARLKK-DQKVLSIRVNR-- QHLKFAIEGARRAAMKFPVKCYY-RRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVY---DPKGDRTL VSAHTR-ELIRDFGWK----GHC-GNTPSAYLLGLLIGYK--AKKAG-IEEAILDIGLHPPVRGSSVFAVLKGAVDAGLN VPHSPEIFPEDYRIRGEHIAEYARMLKEQDEEKFRRQFGGYLEKGLDPEKLPEHFDEVKARIERM-ARASGRDLRISPKL AVEVCRELRGMMLNDALRYLDDVIALRRPVPLKRYNDSQGHKPGK----GFGPGRYPVKVAKAIKKVLLNAQNN----A- KQK--GLDPDKLRIIHIAAHRGPVLRGWYPRAFGRPTPFNEQTTHIEVVVEENLPVRVGDKVRIMRGD------FK-GHE GKVVEVDLKRY--RIY--VEGATLRKTNGT-------------------EVFYPIHPSNVM-IIELNL-----------D --DERRKKI---------------------IERRAG--------MA-------------IE-R--------------Y-- ---FIREAVKEMLIDEFL--EKELR-----RAGYGGLDIKKTP-L-GTKVIIFAANPGYVIGRGGRRIRELTRILERQPQ IDVQEIKN---PYLNAKVQAVRIAQALERGIHFRRAAYAAMRAIMSN-GARGVEIRISGKLTG-ERAKSVRFYQGYLAKV GNPAETLVSKGYAQALLKLGVIGVKVAIMMTLLDPLANALSHITNSERVGKREVYIKPASKLIGEVLRVMQKYGYIGEFE FID----D---G----RAGVYRVQLLGK---INK-------A---GAIKPRFPVKA---RDYERWEKRFLPAFEFGILIV STSQGVMSHKEAREKGIGGRLIAYVY--MQKARIKLASTNVRSLEEVANQIKQIAERTGVRMSGPIPLPTKRIRIVTRKS PDGEGSATFDRWELRIHKRLIDI-EADERAMRQIMRIRVPEDVTIEIELGRVFEGIVVSDKPRKTVTVERQYYHYLKKYE RYELRRSRIHAHNPPC-INAKVGDRVLIAETRPLSKTKHFVVVAVLERA-MARKEFRYRGYTLEQLMNMSLEELAKLLPA RQRRSL-KRGLTPEQKKLLRKIRLAKK---GKYNK----PIRTHCRDMIVLPEMVGLTIYVHNGKEFVPVEIKP-EMIGH YLGEFAPTRKRVQHG----APGIGATR----SSM-FVAVK-- >ARCH_Pyrococcus_furiosus_DSM_3638 Concatenation of 2 sequences M----------GKS----------LIQQ----------------------------R--RGKGSPTF-KSPSHRFRGAVK YIPLNYT----QE-KTLRGVVEEIMHDPGRTAPVARVKFE-NGIEKLIIAPEGLLVGQEIYIGP-D-AP-IAVGNTLPLA KIPEGTYVYNIEGIPGDGGKYVRAGGTYALVVSR--EPDKVIVQLPSGELKAFNPMCRATIGVVAGGGRLEKPLVKAGKA -YYKYKARNKFW-P-TPRGVKMNAVNHPFGGKEHH-----PGKPTTTSR----RAPPGRKVGH-IAARRTG-------RR MGKVHRPRRGSLGFSPRKRAKSIVPRIRSWPKRML---G-FAGYKAGMTHILMIDDEP-GLTNGKEIFMPVTIIETPPLR VFGIR----AYR-------MGY--LGLETAT-------EVIVPYTQ------EMFEQKLGQLDMIKEGEIVDVRAIVATQ PWVIK-LKKKPEVMEYAI-----GGTSVEEKFNYIKEKL---GK-ELRV-GE-V-LKEGELLDVIAVTKGKGTQGPVKRW GIKL---RAHKDSKGRRK-VGSIGP--WHPA-RVMWTVPMAGQMGFHHRTELNKRLIAIGENGKLKLDENTEIEITPKGG FPHYGIVRSDFMMIAGS-VPGAIKRIIRVR--MKVKVFD-LNGQPV-GEIELPKVFF-----T-PF-RPDLIRRAVIASW THRIQPQGRDPMAGK-----------RRVTENI----------GKGHSMAR--------VER---LK-TPPRYAAFVPFA RGGRRTHPPK-VEKIIWEDINKKEKRLALMSAIAATANYDLVRARGHIIDNVPQL-P-LIVVDDL---QKV--------- --QKTRLIV--VGKN---E---GIVLGARNHPGVD-V---------------VVVDNLGVEHLAPGTHPGRLTVWTVSAI ERLRMAVEIPN--------KEQILADWE-AHPMRRPRIEKVTINIGVG----ESGERLTKAEIMLQQLTGQKPIRRKAKK TNRDFGIRRGEPIAVKVTLRGPKAYELLKRLLAAVDNRLKA-------SSFDEHGNVCFGIEEHINIPGVE-----YDPE IGIFGMDVCVTLE-RPGFRVARRKRKRAKIPTRHK-LTKEEGMVYMMEEFGVEIVDAWI-R--EEVEIPEGVEVT-V--- -E-G--Y-KVKVKGPKGELEREF-FWP-G--IQIFTED-GN--VVI----Y-K-DFPRRKDV-AIARTFAAHIRNMIKGV TEGFTYKLKVVYSHFPISVKVQG-DE--VIIENFLGEKAPRKAKI-L-P-GVTVKVR--G-Q-EIIVEG-IDKEAVGQTA ANIEQAT------RITKW---DRR-IFQDGIYIVEKAGKRGVSAVRPTRALPVGAYLTVADNSGAKVIQIIGVVG-TRRR LASAGVGDMVVATVKKGRPD-----------MRHQVVRAVIIRQRKEYRRLDGMRVKFEDNAAVIVT-PEGV-PRGTEIR GPVAREA--AERWVRIGSIASIIV-------MIRRRK---KVRKLRGS-HTHGWGCKKKHRGGGSKGGRGMAGTGKRNKS KWTWT-I--KYAPD--HLGK-RG--FSRVNLKFIMQMGIAYEEGGKIIDK---------VLG--TGK-L-T-R-P-LVI- KARAFSPKAEEKIKAAGGEAMY--VDKPAYTRREYIRGAPGPKITIFDMG----NPAGDFEFEVSLHTAEPVQIRQNALE AARQQVNRYLQKNVG-RSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARLKK-DQKILSIRVNR-- QHLKFAIEGARRAAMKFPCKCYY-RRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVY---DPKGDRTL VSAHTR-ELIRDFGWK----GHC-GNTPSAYLLGLLIGYK--AKQAG-IEEAILDIGLHPPVRGSSVFAVLKGAVDAGLN VPHSPEIFPDEYRIRGEHIAEYAKMLKEQDEEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIKRM-ARASARDLRISPKL AVEVCRELRGMMLNDALRYLDDVIALKRPVPLKRYNDSQGHKPGK----GFGPGRYPVKVAKAIKKVLLNVKNN----A- VQK--GLDPDKLKIIHIAAHKGPVLRGWYPRAFGRATPFNEQTTHIEVVVEENLPVRVGDKVRIMRGD------YK-GHE GKVVEVDLKRY--RIY--VEGATLRKTNGT-------------------EVFYPIHPSNVM-IIELNL-----------E --DEKRKKI---IE------------------RRAG--------MA-------------IE-R--------------Y-- ---FIREAVREMLIDEFL--EKELR-----RAGYGGLDIKKTP-L-GTKVIIFAANPGYVIGRGGRRIRELTRILEKQPQ IEVEEIKN---PYLNAKVQAVRLAQALERGIHFRRAAYAALRAIMNN-GARGVEIRLSGKLTG-ERAKSIRFYQGYLAKV GNPAETLVSKGYAQALLKLGVIGVKVAIMMTLLDPLANALSHITNSERVGKREVYIKPASKLIGEVLRVMQKYGYIGEFE FID----D---G----RAGVYRVQLLGR---INK-------A---GAIKPRFPVK---VSEFEKWEKRFLPAFEFGILIV STSQGVMSHKEAIEKGIGGRLIAYVY--MQKARIKIASTNVRSLDEVANQIKQIAERTGVRMSGPIPLPTKRIRITTRKS PDGEGSATFDRWELRVHKRLIDI-EADERAMRQIMRIRVPEDVTIEIELGRVFEGIVVSDKPRKTVTVERQYYFYLNKYE RYELRRSKIHAHNPPC-INAKVGDKVLIAETRPLSKTKHFVVVAVLERA-MARKEFRYRGYTLEQLMNMSLEELARLFPA RQRRSL-KRGLTPEQKKLLRKIRLAKK---GKYKK----PIRTHCRDMIILPEMVGLTIYVHNGKEFVPVEIKP-EMIGH YLGEFAPTRKKVEHG----APGVGATR----SSM-FVAVK-- >ARCH_Pyrococcus_horikoshii_OT3 Concatenation of 2 sequences M----------GKS----------LIQQ----------------------------R--RGKGSPTF-RSPSHRFRGAVK YIPLNYT-Q--DK--TIRGVVEEIMHDPGRTAPVARVKFE-NGMEKLIIAPEGLLVGQEIYIGP-D-AP-VEIGNTLPLA KIPEGTYIYNIEGVPGDGGKYVRAGGTYALVVSR--EKDKVIVQLPSGELKAFDPNCRATIGVVAGGGRLEKPLVKAGKA -YYKYKARNKFW-P-TPRGVKMNAVNHPFGGKEHH-----PGKPTTTSR----RAPPGRKVGH-IAARRTG-------RR MGKIHRPRKGSLAFSPRKRAKSIVPRIRSWPKTEVRMLG-FAGYKAGMTHILMIDDEP-GLTNGKEIFMPVTIIETPPLR VFGIR----AYR-------QGY--LGLETA--------GEVIVLPK--DYTQEEFEQKLGALDMIKEGEIVEVRALVSTQ PWVIK-LKKKPEVMEYAI-----GGTSVEEKFNYIKEKL---GK-EIRV-GE-V-LKEGELLDVIAVTKGKGTQGPVKRW GIKL---RAHKDSKGRRK-VGSIGP--WHPA-RVMWTVPMAGQMGFHHRTELNKRLIAIGENGK-LVIDGNEIEITPKGG FPHYGIVRGDFMMIAGS-VPGAIKRIIRVR--MKVKVFD-LNGQPV-DEIELPRVFL-----T-PF-RPDLIRRAVIASW THRIQPQGRDPMAGK-----------RRVTENI----------GKGHGMAR--------VER---LK-TPPRYAAFVPFA RGGRRAHPPK-VEKIIWEGINKKERRLAIMSAIAATANYDIVKSRGHIVDNVPQL-P-LIVVDDL---QKV--------- --SKTRLIV--VGKN---E---GIVFGARNHPGVD-V---------------VVVDNLGVEHLAPGTHPGRLTVWTVSAI ERLRMPVSIPNREEI----LAD-----WEAHPMRRPRIQKVTINIGVG----ESGERLTKAEIMLQRLTGQKPIRRKAKK TNRDFGIRRGEPIAVKVTLRGPKAYEMLKRLLAAVDYKLKA-------SSFDEHGNVCFGIEEHINIPGVE-----YDPE IGIFGMDVCVTLE-RPGFRVARRKRKRARIPTRHK-LTKEEGMLYMMEEFGVEIVDAWI-R--EEIEIPEGVEVS-V--- -Q-D--Y-NVKVKGPKGEVEKKL-FWP-G--VKIFVED-GK--VVI----Y-K-DFPRRKDV-AIVRTFKAHINNMIKGV TEGFTYKLKVVYSHFPITVKVQG-DE--VIIENFLGEKAPRRAKI-L-P-GVTVKVK--G-Q-EIIVEG-IDKEATGQTA ANIEQAT------RITKW---DRR-VFQDGIYIVEKAGKRGISPVRPTRAIPIGAYLTVADNSGAKVIQVIGVVG-TRRR LASAGVGDMVVATVKKGRPD-----------MRHQVVRAVIIRQRKEYRRLDGMRVKFEDNAAVIVT-PEGV-PRGTEIR GPVAREA--AEKWVRIGSIASIIVAR-M--IRRRK-----KVRKLRGS-HTHGWGCKKKHRGGGSKGGRGMAGTGKRNKS KWTWT-I--KYAPD--HLGK-RG--FSRVTLKFILQMGIAYEEEGKIVDK---------VLG--TGR-L-T-R-P-LTI- KAKAFSAKAEEKIKAAGGEVMY--VDKPAYTRREYIRGAPGPKITIFDMG----NPAGDFEFEVALHTAEPVQIRQNALE AARQQVNRYLQKNVG-RSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARLKR-DQKILSIRVNR-- QHLKFAIEGARRAAMKFPCKCYY-RRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVY---DPKGDRTL VSAHTR-ELIRDFGWK----GHC-GNTPSAYLLGLLIGYK--AKKAG-IEEAILDIGLHPPVRGSSIFAVLKGAIDAGLN VPHSPEIFPEDYRIRGEHIAEYARMLKEQDEDRFRRQFGGYLEKGLDPEKLPEHFEEVKARIERM-ARASGRDLRISPKL AVEVCRELRGMMLNDALRYLDEVIALKRPVPLRRYNDSQGHKPGK----GFGPGRYPVKVAKAIKKVLLNAKNN----A- EQK--GLDPDKLKIIHIAAHRGPVLRGWYPRAFGRATPFNEQTTHIEVVVEENLPVRVGDKVRIMRGD------FK-GYE GKVVEVDLKRY--RIY--VEGVTLRKVNGT-------------------EVFYPIHPSNVM-IIELNL-----------D --DEKRKKI---------------------IERRAG--------MA-------------IE-R--------------Y-- ---FIREAVKEMLIDEFL--EKELR-----RAGYGGLDIKKTP-L-GTKVIIFAANPGYVIGRGGRRIRELTRILERQPQ IDVQEIKN---PYLNAKVQAVRIAQALERGIHFRRAAYSAMRAIMNN-GARGVEIRLSGKLTG-ERAKSVRFYQGYLAKV GNPAETLVSKGYAQALLKLGVIGVKVAIMMTLLDPLANALSHITNSERVGKREIYIKPASKLIGEVLRVMQKYGYIGEFE FID----D---G----RAGVYRVQLLGR---INK-------A---GAIKPRFPVKATE---YEKWEKRFLPAFEFGILIV STSQGVMSHKEARDRGIGGRLIAYVY--MQKARIKLASTNVRSLEEVANQIRQIAERTGVRMSGPIPLPTKRIRIVTRKS PDGEGSATFDRWELRIHKRLIDI-EADERAMRQIMRIRVPEDVTIEIELGRVFEGIVISDKPRKTVTVERQYYHYLKKYE RYELRRSRIHAHNPPC-INAKVGDRVLIAETRPLSKTKHFVVVAVLERA-MARKEFRYRGYTLEQLMNMSLEELARLLPA RQRRSL-RRGLTPEQKKLLRKIRLAKK---GKYNK----PIRTHCRDMIILPEMVGLTIYVHNGKEFVPVEIKP-EMIGH YLGEFAPTRKRVQHG----APGIGATR----SSM-FVAVK-- >ARCH_Staphylothermus_marinus_F1 Concatenation of 2 sequences M----------GKR----------ILPQ----------------------------R--MGRGTPTF-RSPSHRRVGPAK YPPLKLD-R------TIKGKIIDLLHDPGRWVPLAKIVLE-DGTTFLTPAVEGMYVGQIIEIGP-D-AH-ISNGNILPIG KIPEGTQIANIEKRPGDGGKFVRSSGTYALIVGR--AGTKTQVQLPSGKIIEVPNNARATIGVIAGGGRDEKPLLKAGNA -YHKWKVKAKKW-P-KVRGVAMNAVSHPHGGGSHQH----VGKPSTVAR----ETPPGRKVGH-IAARRTG-------RR HRKYSAPRHGSLGVRPRKRAAKIVPRIRSWPTVLL---G-YVAYKAGMSHAIIIDDRPHTFTSGKEIAIPVTVLDAPPIL ILGLR----GYK----I--HPW--RSPVEAL-------KE--LVRK----------YLKGLRERLKAAELADIRVIASTI PVLSGIGKKKPEIIEIKI-GGGTLSERIDYAE-----KLL--GN-YVTV--DQV-FREGQFIDIIGVTKGKGFQGVIKRF GVKE-LPRWHKHRKGSRK-IGS-----RSPGFGTMSETPQPGQMGFHRRTEYNKRIIKIGINGW---------EVTPKGG FLGYGIVYGPYIMLHGS-IIGPRKRLLVLRERQETYVFS-SDGEKV-EEITLPP-IF----SL-PV-RKDLIRRAFLSAF TSMLQPKGRDPLAGK-----------RTTARSW----------GVGRGLAR--------------VPRLPNSRAAFISFA RGGHAAFPPR-PDERIHERINKREKAYAVASAIAATAKVDLVRGRGHVFQQDKL--P-VVLLDDV--EDKI--------- --SKARLFV--VTSYD--K---PFAKAVRNFPGVD-V---------------ATPNNLGILHLAPGGVPGRLTVFTRSAI EDISSTIIEHVPD------ADKIIEKWN-SNPMYKPRLAKVTVNISVG----AATERLSKAMQVLEELTGQKPVPRRAKR TIKDFGIRKGENIAAKVTLRREKAVAFLKRVLEAVNYRIKA-------SSFDDNGNVSFGIKEHIMIPGVK-----YDPE IGVFGMDVAITIE-RPGYRVLRRKRCRKKHIPRRHRVSREEAMLYLHKEFGVEIMVKLP-HIYEEIDIPENVTVE-I--- -N-G--L-KVKVNGPKGSIERDF-SHVRN--IILRKEN-SK--IIV----E-T-FFADRRKK-ALVGTIASHIENMIKGV LKGYRYKLKIIYSHFPITVEVDD-RNRIVRIKNFLGEKSDRIAKI-IGE-DVKVTVK--G-E-DIIVEG-IDIEHVGQTA ANIELAT------KVKD----KDRRVFADGIYIYDWGEEPAFSRRRIATGLQVGSYVRVADNSGAKLVKIIGVPG-RLRR IPPAGIGDLVVVTVKKGTPE-----------MRKQVVKAVIVRQKRPFRRPDGTWVAFEDNAVAIVT-PEGT-PKGSEIR GPIAKEV--AERWPQLANIATIVV------MVVRKKK---KSRKLRGRTRSMGWGRIGQHRKSGARGGFGAVGFHKHK-- -WIWV-L--KYAPNWY--GK-HG--FTRINVGELVSKNLAYREEGKIVNK---------VLG--RGK-V-T-L-P-LKI- ITKSISKRAREKITAVGGEVMH--FSGPPYTRREYIPGVPQPKIVKFEMG----NVHGDYDYRAELVMIEAGQIRHNALE AARVMANKYLSSTVG-DQNYFLKIRVYPHHVLRENKMMAFAGADRLQDGMRQAFGKPIGTAARVYP-GTIVMEVRVRK-- EHVEHAKEALRRAASKLPLPARI-VKVPKRRRREGKTNYYKRYKMVLSGHPRFVVRKTLKHIIVQIVTA---KPEGDITI AAAHSR-ELYKKYGWM----GGL-GNTPAAYLTGLLAALR--GLKAG-IKYAVPDIGLHVPTRGAKVFAAIKAANDVGLK VPVGEEVVPSDDRIRGEHIASWAKMLQEASPEAYERFFSKYISRGFDPTQLPTHFEEVKNRISRI-AKAVQFDIPVSIKD MREAVAAIRGKKVSEAKKLLENVIALREPIPFKRYKGKLSHKRGLPAKWKWPIGRYPVKAAKYLLRLLEHVEAN----A- DNK--GLDKDKLVIVHIAAHKGMTLKRWMPRAFGRATPKFRRTSHVEIVVKEKLPVRKGDVVRIMRGD------WK-GHE GKVVRIDLRRV--RLY--VEGVQRKKADQT----PV---------------YYPIHPSKVM-IIKLDL-----------S --DKWRRKIEVVEE--------KETSK---TSEGGGKTIEETM-TRPRVKSY---------------------------- ---FIDYSLKKVMLDEFL--ANYFK-----DAGYAGMELYKTP-T-GYRVVIYAEYPGRIIGRGGSIIRKLMTIMQTHVN ITVSPVPD---PDLNARIVAFRIVRALEKEIPYRRVAMAMLRRVMEA-GAVGAEIIISGKLRS-ERARYEKLKAGRIYKA GDMVDYVVDRAVGKALLKRGVYGVEVVIVMVMLDTLANALATIQNAEMRAKSEALIWPASKLIINVLRVMQREGYIGEFE YID----D---G----RWGKIKVQLLGR---INK-------T---GVIKPRFPVKLRDLERMPHWLRKYLPAYNIGILIL STPHGVLSHKEAIAKKTGGVLLAYVYSTPRMVKIKIWSNNINILNEFMNKITDIVKRTGVKMSGPIPLPTKRLVVRTLKL PHGEGKKKWEKWEMRIHKRLLYI-AADERVMKQLIRVRVPPEIWMEIEIGQILRGVVVKAKMHRTVVVRHDYYYYVRKYR RYEKRHTHIHAHNPPC-INAKEGDEVLIGETRPLSKTVHFVVLGIIKRAPPEWKKFRYRGKTLEELLNMPMDEFIGLLPA RQRRSL-KRGLTMAQVKLLAKIRKVRQKKLTGKKA----IIKTHVRDMIILPEMIGLTIAVYNGKEFIPVRIVP-EMIGH YLGEFSPTTKRVQHG----EPGLKATR----SSM-FISLK-- >ARCH_Sulfolobus_acidocaldarius_DSM_639 Concatenation of 2 sequences MGKKL-------------------LQQR-------------------------------AGRGGINF-RSPSWRRVGPAR YPNIEGD----HK-----GKIIDILHNPGVTAPVVKVKLD-NGLQFYIPAVQGVAVGQEISIGK-N-AT-ISNGNIVEVG QLPEGTVICNVEKLKGDGGKFARAAGSYAVISGK--AGNKVLIKLSSEKIVEVSQNARATVGIIAGGGFVEKPLLKAGNN -YWKYRVRAVKW-P-VVRGVAMNAVSHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IASRRTG-------RR HRKLSSPRRGSAGLRPRKRADEILPTPKNWPLKLL---G-FIGYKAGMTHVYMIDDKPTSPNYGKEVYTPVTIVESPPIL GLALR--AYHID----S--KGE--LSVLVDY------WANFEEKMK----------EKLDLIQKNLNNITYMRLLVSTQP WLVPSLGKKRPEIVEIQI---GGGSIQDQLNY-----GLSLLGK-QIPV--RDV-FREGQLTDIIGVTKGKGFQGVIKRY SVVE-FPRWHKHRKGSRK-IGARGPSISTPS-----YVPQPGQLGFHRRTEYNKRIIKIGDNVN---------EINPAGG IVNYGLVKNTYLVIEGS-VLGSRKRPLFLRQTKKVSVLD-LKGNQL-EEIELPL-FF----SY-PV-RKDLIRRVFLSEF TKSLQPKGRDPLAGKRTSALSFGINLGIARVP----------RVKGSGEAA--------------L--AP----NT---- VGGRLAFPPT-TEKRLVEEVNLKEKKLGIISALAATADPNFVKARGHRFTSNNV--P-IILVDDF---ENI--------- --SKAKLIV--VSNHK--S---PVVESASNIPGVN-V---------------VSANLVSVIHLAPGGHPGRLTIYTKSSI NILRMSMQEAKKENV-----------------MRRVVLDKVTVNIGVG----ESGERLQKAYQLVQELTGVKPVYTKGRK SIREFGVRKGAPIGVKATLRRQAAVEFLKKVLPAVNFRLKQ-------SSFDNYGNVSFGIAEHVLIPGTR-----YDPE IGIFGMDVAITLV-RPGYRTMKRKRKKASIPRRHR-VTKEEAINFMKENFNVTIKAAYI-R--EEIQIPDKVKVS-L--- -E-N--N-VLKVKGPKGEVIKDF-SYAKG--IRIQLNE-GK--IIL----E-T-TFADRRKK-ALLYSIIAHIKNMITGT INGYRYYLKVISTHFPISVKVSG-DE--VQVSNLIGEKNIRRAKI-L-P-GVKVTVK--G-E-DIVVEG-SDIYNVAQTA ANIESST------KIVGY---DRR-IFSDGIYIYKKEVIVLGSRKGFTPALQHNSSVVVADNSGAKEAVIIGIYG-VLRR VPFANIADLVMVSVRKGSPD-----------VRKQKFKAVIVRQRMPFRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASVATMVI------MVVRKE----KKSRKYRGYRTHGWGTKGQHRDRGAQGGRQIGMHKEK--- -WSWTVK-FGEGWY----GK-HG--FRNIGLRKLIKIEEENGK-KVVDDK---------LLG--GGN-L---RLP-LVI- KVAKATEKAKERVKEIGGEIMK--FSGPAYTRREYIPGIPMPKITKFVMG----NVNGDYDYELRLITTEKGQIRHNALE AARVIALKYLSKKLASEQNFALVVTKYPHHVIRENKMMAFAGADRLQDGMRLSFGKPIGTAARLEKLGELVMYVRVKK-- EHLEAAKEALKIASSKLPIRTKI-ERIKFRRRREGKTDYYTRYTYVINNAIRFVPRLTNKYVIVSVSKF---DQKGDIMI AYAHSI-ELVKKYGWK----GDT-NNTPAAYLTGYLAGLR--AVKSG-VKAAVSDIGLFVPVKGGRIFAVIKGAIDAGLK V-PVGDLGKLKDRVNGSHISAYAQKLKNENQELYNKLFSSYIQRGLDPVLLPQHFEEVLNKIDKL-AKAVIKNIDASVRD LYNVCKAIRGMNLKEAREFLNNVLEEKEALPFWRYSHGTSHRSNISRKWKVKSGRYPKKAIKYVLKLLDNAENN----A- NSK--GLDIDNLKIVHIAAHKGLVLKRYMTRAFGRSTRKYKYLSHIEVILGERISIRKGDSVKLMRGS------QV-GYE GKVVEVDRKRG--RVA--IEGLTKKKADGT----PV---------------YVWVHASKVI-ITKLDT-------GD--K --ERMDAIE-------------RKKMR-EYFSKKSP---KEV--M--------------VLIK----------------R H--FLQKAAIKVMVDEYL--AKQFY-----NAEYAGVEIVKTP-I-GTRVIIYAGRPPLIIGKGGKTIKQLAQVLEKFPQ ITVTAAEN---PELNARVMAFRLAIALEKGYHFRRAAFITIRRIMSS-GAVGAEVIVSGKLTS-ERAKYEKLKEGTVYKS GQQLEKIIDRAIGIAMLKPGVYGVEVVITVPSINPLANALATLYNNEMRRNKQALITPASKLIISVLRVMQKEGYIGEFE YID----D---G----RAGKIIVQLLGR---INK-------C---GPISPRYPLDYNGLLRLPDYIRKYLPSKEIGIIII STPKGVMSHRDGIREKIGGVTLGYVY-MPTKARIRLWSSNIDSLNFVVNQIRNMAQKTGIQVSGPIPLPTTRMEVPVMRL PHGEGKKKWEHWEMKVHKRIIDI-AADERVMRQLMRVRVPDDVYIEIELGIVLEGKLIRARANRTGTVEREYIFYDSKYK RYERRRSRIHVHIPSC-LEVKEGDNVIIGESRPIAKSISFVILGVK---PPEWKKFRYRGKSLEDLLNMPMDEFIKLLPS RQRRSL-KRGFSDKQRRLLEKIRKISR---EGKQN---KVIKTHVRNMVILPEMVGLRFAVYNGKEFVEFQVVP-EMIGR YLGEYSITTKKVEHG----EPGLKATK----SSL-FLAMKG- >ARCH_Sulfolobus_islandicus_LS215 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RSPSWLRI---- -GKVRYP----NIFGHLVGKVIDIVHNPGMNAPVAIIKLE-NGTKFLTQAIQGLVINQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQKLL---G-FVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----V--DGW--SPSSLQF-------LDITRSKK----------KFEEKFKSNLDRIVYFRLLVATQP RKIPSLGKKVPDLVEIQI---GGGEKKAQLDY-----ALNVLGK-EISI--KDV-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPSLGTPS-----YTPQPGQLGFHRRTEYNKRIIKIGDDPK---------EINPAGG FVRYGIVRNTYILLEGS-ILGSKKRPIFLRVKKNSVILD-KDGNKV-KEVELPF-IF----SF-PV-RKDIIRRVFLAEF THSLQPKGRDPMAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLTFPPS-VDKKLVEEANDKEKQLAVISALSATADKVFVKARGHVFKDSVSF-P-IVVTDDI---VSL--------- --KTASLII--VHDSN--S---PIVKAARNIAGVD-V---------------VNAKDVSVIHLAPGTHSGRLTIYTETSI KILD-------MTES----TLSVNQ-----NPMRKVKLAKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGTQAEGFLRKVLEAIGYRLKK-------SSFDEYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKTRIPRRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPSNVNVD-L--- -K-D--S-VIKMKGPKGEVVKDF-SFARG--IQISLDG-NK--IVL----E-T-TFANRRKK-AAFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNIRRAPI-L-Q-GVKVTVK--G-E-DIVVEG-PNLDAVAQTA ANIEAAS------KITGF---DRR-IFSDGIFIYKKEVVVLGSRKGLTPSLQHYSVVNVADNSGAKEAMIIGVYG-VLRR VPFANIADMVMVSVKRGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FRNISLRKLIKIKEIDGK-KIVDDK---------LLG--GGI-I-S-V-P-VTI- KVGKATDRAIQKVKQIGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKK-- EHLDFAKEALKIASKKLPLRTRIEIKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKI---DPKGDIMV ASAHSS-ELTKKFEWK----GDE-NNTPSAYLTGYLAALR--AVKKG-VTECVADIGLHVPSKGNKVFYAIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKILKI-AKAVIRDVPASIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKANISAKWKIKAGRYPKKAIRQVLKLLENAEAN----A- TNK--GLDIDKLIIRHIAAHKGITLERYMPRAFGRATAKYRRTSNVEVILEERIRVRKGDTVRVMRGN------HN-GKE GKVTEINTRTG--RLA--IEGITRKKTDGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------M-----------------K----------------- -----------VKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYIRRYLPSKEIGIIIV STSKGVMSHKEAARMRLGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGIILEGVIVKYKGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-VNVREGDKVIIGECRPLSKSISFVVLS---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKIRKYRR---EGKVN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_islandicus_M1425 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RSPSWLRI---- -GKVRYP----NIFGHLVGKVIDIVHNPGMNAPVAIIKLE-NGTKFLTQAIQGLVINQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQKLL---G-FVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----V--DGW--SPSSLQF-------LDITRSKK----------KFEEKFKSNLDRIVYFRLLVATQP RKIPSLGKKVPDLVEIQI---GGGEKKAQLDY-----ALNVLGK-EISI--KDV-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPSLGTPS-----YTPQPGQLGFHRRTEYNKRIIKIGDDPK---------EINPAGG FVRYGIVRNTYILLEGS-ILGSKKRPIFLRVKKNSVILD-KDGNKV-KEVELPF-IF----SF-PV-RKDIIRRVFLAEF THSLQPKGRDPMAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLTFPPS-VDKKLVEEVNDKEKQLAVISALSATADTVFVKARGHVFKDSVSF-P-IVVTDDI---VSL--------- --KTASLII--VHDSN--S---PIVKAARNIAGVD-V---------------VNAKDVSVIHLAPGAHPGRLTIYTETSI KILD-------MTES----TLSVNQ-----NPMRKVKLAKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGTQAEGFLRKVLEAIGYRLKK-------SSFDEYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKTRIPRRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPSNVNVD-L--- -K-D--S-VIKMKGPKGEVVKDF-SFARG--IQISLDG-NK--IVL----E-T-TFANRRKK-AAFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNIRRAPI-L-Q-GVKVTVK--G-E-DIVVEG-PNLDAVAQTA ANIEAAS------KITGF---DRR-IFSDGIFIYKKEVVVLGSRKGLTPSLQHYSVVNVADNSGAKEAMIIGVYG-VLRR VPFANIADMVMVSVKRGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FRNISLRKLIKIKEIDGK-KIVDDK---------LLG--GGI-I-S-V-P-VTI- KVGKATDRAIQKVKQIGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKK-- EHLDFAKEALKIASKKLPLRTRIEIKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKI---DPKGDIMV ASAHSS-ELTKKFEWK----GDE-NNTPSAYLTGYLAALR--AVKKG-VTECVADIGLHVPSKGNKVFYAIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKILKI-AKAVIRDVPASIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKANISAKWKIKAGRYPKKAIRQVLKLLENAEAN----A- TNK--GLDIDKLIIRHIAAHKGITLERYMPRAFGRATAKYRRTSNVEVILEERIRVRKGDTVRVMRGS------HN-GKE GKVTEINTRTG--RLA--IEGITRKKADGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------M-----------------K----------------- -----------VKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYIRRYLPSKEIGIIIV STSKGVMSHKEAARMRLGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGITLEGVIVKYKGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-VNVREGDKVIIGECRPLSKSISFVVLS---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKIRKYRR---EGKVN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_islandicus_M1627 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RSPSWLRI---- -GKVRYP----NIFGHLVGKVIDIVHNPGMNAPVAIIKLE-NGTKFLTQAIQGLVINQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQKLL---G-FVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----V--DGW--SPSSLQF-------LDITRSKK----------KFEEKFKSNLDRIVYFRLLVATQP RKIPSLGKKVPDLVEIQI---GGGEKKAQLDY-----ALNVLGK-EISI--KDV-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPSLGTPS-----YTPQPGQLGFHRRTEYNKRIIKIGDDPK---------EINPAGG FVRYGIVRNTYILLEGS-ILGSKKRPIFLRVKKNSVILD-KDGNKV-KEVELPF-IF----SF-PV-RKDIIRRVFLAEF THSLQPKGRDPMAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLTFPPS-VDKKLVEEVNDKEKQLAVISALSATADTVFVKARGHVFKDSVSF-P-IVVTDDI---VSL--------- --KTASLII--VHDSN--S---PIVKAARNIAGVD-V---------------VNAKDVSVIHLAPGAHPGRLTIYTETSI KILD-----MTESTL----------SVN-QNPMRKVKLAKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGTQAEGFLRKVLEAIGYRLKK-------SSFDEYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKTRIPRRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPSNVNVD-L--- -K-D--S-VIKMKGPKGEVVKDF-SFARG--IQISLDG-NK--IVL----E-T-TFANRRKK-AAFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNIRRAPI-L-Q-GVKVTVK--G-E-DIVVEG-PNLDAVAQTA ANIEAAS------KITGF---DRR-IFSDGIFIYKKEVVVLGSRKGLTPSLQHYSVVNVADNSGAKEAMIIGVYG-VLRR VPFANIADMVMVSVKRGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FRNISLRKLIKIKEIDGK-KIVDDK---------LLS--GGI-I-S-V-P-VTI- KVGKATDRAIQKVKQIGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKK-- EHLDFAKEALKIASKKLPLRTRIEIKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKI---DPKGDIMV ASAHSS-ELTKKFEWK----GDE-NNTPSAYLTGYLAALR--AVKKG-VTECVADIGLHVPSKGNKVFYAIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKILKI-AKAVIRDVPASIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKANISAKWKIKAGRYPKKAIRQVLKLLENAEAN----A- TNK--GLDIDKLIIRHIAAHKGITLERYMPRAFGRATAKYRRTSNVEVILEERIRVRKGDTVRVMRGS------HN-GKE GKVTEINTRTG--RLA--IEGITRKKADGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------M-----------------K----------------- -----------VKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYIRRYLPSKEIGIIIV STSKGVMSHKEAARMRLGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGITLEGVIVKYKGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-VNVREGDKVIIGECRPLSKSISFVVLS---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKIRKYRR---EGKVN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_islandicus_M164 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RSPSWLRI---- -GKVRYP----NIFGHLVGKVIDIVHNPGMNAPVAIIKLE-NGTKFLTQAIQGLVINQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQKLL---G-FVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----V--DGW--SPSSLQF-------LDITRSKK----------KFEEKFKSNLDRIVYFRLLVATQP RKIPSLGKKVPDLVEIQIG---GGEKKAQLDY-----ALNVLGK-EISI-KD-V-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPS-LGTP-SYT---PQPGQLGFHRRTEYNKRIIKIGDDPK---------EINPAGG FVRYGIVRNTYILLEGS-ILGSKKRPIFLRVKKNSVILD-KDGNKV-KEVELPF-IF----SF-PV-RKDIIRRVFLAEF THSLQPKGRDPMAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLTFPPS-VDKKLVEEVNDKEKQLAVISALSATADTVFVKARGHVFKDSVSF-P-IVVTDDI---VSL--------- --KTASLII--VHDSN--S---PIVKAARNIAGVD-V---------------VNAKDVSVIHLAPGAHPGRLTIYTETSI KILD-----MTESTL----------SVN-QNPMRKVKLAKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGTQAEGFLRKVLEAIGYRLKK-------SSFDEYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKTRIPRRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPSNVNVD-L--- -K-D--S-VIKMKGPKGEVVKDF-SFARG--IQISLDG-NK--IVL----E-T-TFANRRKK-AAFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNIRRAPI-L-Q-GVKVTVK--G-E-DIVVEG-PNLDAVAQTA ANIEAAS------KITGF---DRR-IFSDGIFIYKKEVVVLGSRKGLTPSLQHYSVVNVADNSGAKEAMIIGVYG-VLRR VPFANIADMVMVSVKRGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FRNISLRKLIKIKEIDGK-KIVDDK---------LLG--GGI-I-S-V-P-VTI- KVGKATDRAIQKVKQIGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKK-- EHLDFAKEALKIASKKLPLRTRIEIKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKI---DPKGDIMV ASAHSS-ELTKKFEWK----GDE-NNTPSAYLTGYLAALR--AVKKG-VTECVADIGLHVPSKGNKVFYAIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKILKI-AKAVIRDVPASIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKANISAKWKIKAGRYPKKAIRQVLKLLENAEAN----A- TNK--GLDIDKLIIRHIAAHKGITLERYMPRAFGRATAKYRRTSNVEVILEERIRVRKGDTVRVMRGS------HN-GKE GKVTEINTRTG--RLA--IEGITRKKADGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------M-----------------K----------------- -----------VKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYIRRYLPSKEIGIIIV STSKGVMSHKEAARMRLGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGITLEGVIVKYKGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-VNVREGDKVIIGECRPLSKSISFVVLS---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKIRKYRR---EGKVN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_islandicus_YG5714 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RSPSWLRI---- -GKVRYP----NIFGHLVGKVIDIVHNPGMNAPVAIIKLE-NGTKFLTQAIQGLVINQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQPNPKLLG-FVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----V--DGW--SPSSLQF-------LDITRSKK----------KFEEKFKSNLDRIVYFRLLVATQP RKIPSLGKKVPDLVEIQI---GGGEKKAQLDY-----ALNVLGK-EISI--KDV-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPSLGTPS-----YTPQPGQLGFHRRTEYNKRIIKIGDDPK---------EINPAGG FVRYGIVRNTYILLEGS-ILGSKKRPIFLRVKKNSVILD-KDGNKV-KEVELPF-IF----SF-PV-RKDIIRRVFLAEF THSLQPKGRDPMAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLTFPPS-VDKKLVEEVNDKEKQLAVISALSATADKVFVKARGHVFKDSVSF-P-IVVTDDI---VSL--------- --KTASLII--VHDSN--S---PIVKAARNIAGVD-V---------------VNAKDVSVIHLAPGAHSGRLTIYTETSI KILD-----MTESTL----------SVN-QNPMRKVKLAKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGTQAEGFLRKVLEAIGYRLKK-------SSFDEYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKTRIPRRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPSNVNVD-L--- -K-D--S-VIKMKGPKGEVVKDF-SFARG--IQISLDG-NK--IVL----E-T-TFANRRKK-AAFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNIRRAPI-L-Q-GVKVTVK--G-E-DIVVEG-PNLDAVAQTA ANIEAAS------KITGF---DRR-IFSDGIFIYKKEVVVLGSRKGLTPSLQHYSVVNVADNSGAKEAMIIGVYG-VLRR VPFANIADMVMVSVKRGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FRNISLRKLIKIKEIDGK-KIVDDK---------LLG--GGI-I-S-V-P-VTI- KVGKATDRAIQKVKQIGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKK-- EHLDFAKEALKIASKKLPLRTRIEIKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKI---DPKGDIMV ASAHSS-ELTKKFEWK----GDE-NNTPSAYLTGYLAALR--AVKKG-VTECVADIGLHVPSKGNKVFYAIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKILKI-AKAVIRDVPASIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKANISAKWKIKAGRYPKKAIRQVLKLLENAEAN----A- TNK--GLDIDKLIIRHIAAHKGITLERYMPRAFGRATAKYRRTSNVEVILEERIRVRKGDTVRVMRGN------HN-GKE GKVTEINTRTG--RLA--IEGITRKKADGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------M-----------------K----------------- -----------VKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYIRRYLPSKEIGIIIV STSKGVMSHKEAARMRLGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGIILEGVIVKYKGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-VNVREGDKVIIGECRPLSKSISFVVLS---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKIRKYRR---EGKVN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_islandicus_YN1551 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RSPSWLRI---- -GKVRYP----NIFGHLVGKVIDIVHNPGMNTPVAIIKLE-NGTKFLTQAIQGLVINQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQPNPKLLG-FVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----V--DGW--SPSSLQF-------LDITRSKK----------KFEEKFKSNLDRIVYFRLLVATQP RKIPSLGKKVPDLVEIQI---GGGEKKAQLDY-----ALNVLGK-EISI--KDV-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPSLGTPS-----YTPQPGQLGFHRRTEYNKRIIKIGDDPK---------EINPAGG FVRYGIVRNTYILLEGS-ILGSKKRPIFLRVKKNSVILD-KDGNKV-KEVELPF-IF----SF-PV-RKDIIRRVFLAEF THSLQPKGRDPMAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLTFPPS-VDKKLVEEVNDKEKQLAVISALSATADKVFVKARGHVFKDSVSF-P-IVVTDDI---VSL--------- --KTASLII--VHDSN--S---PIVKAARNIAGVD-V---------------VNAKDVSVIHLAPGAHSGRLTIYTETSI KILD-------MTES----TLSVNQ-----NPMRKVKLAKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGTQAEGFLRKVLEAIGYRLKK-------SSFDEYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKTRIPRRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPSNVNVD-L--- -K-D--S-VIKMKGPKGEVVKDF-SFARG--IQISLDG-NK--IVL----E-T-TFANRRKK-AAFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNIRRAPI-L-Q-GVKVTVK--G-E-DIVVEG-PNLDAVAQTA ANIEAAS------KITGF---DRR-IFSDGIFIYKKEVVVLGSRKGLTPSLQHYSVVNVADNSGAKEAMIIGVYG-VLRR VPFANIADMVMVSVKRGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FRNISLRKLIKIKEIDGK-KIVDDK---------LLG--GGI-I-S-V-P-VTI- KVGKATDRAIQKVKQIGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKK-- EHLDFAKEALKIASKKLPLRTRIEIKIKHRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKI---DPKGDIMV ASAHSS-ELTKKFEWK----GDE-NNTPSAYLTGYLAALR--AVKKG-VTECVADIGLHVPSKGNKVFYAIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKILKI-AKAVIRDVPASIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKANISAKWKIKAGRYPKKAIRQVLKLLENAEAN----A- TNK--GLDIDKLIIRHIAAHKGITLERYMPRAFGRATAKYRRTSNVEVILEERIRVRKGDTVRVMRGN------HN-GKE GKVTEINTRTG--RLA--IEGITRKKADGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------M-----------------K----------------- -----------VKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYIRRYLPSKEIGIIIV STSKGVMSHKEAARMRLGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGIILEGVIVKYKGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-VNVREGDKVIIGECRPLSKSISFVVLS---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKIRKYRR---EGKVN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_solfataricus_P2 Concatenation of 2 sequences M------------------------------------------GKNLLQQR--------AGKGSPTF-RNPGWLRI---- -GKVRYP----NIFGHFIGKVIDIVHNPGMNAPVALVKLE-NGTKFLMQAIQGLVVNQKIEFGK-G-SP-IANGNVIEIG DAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGK--SGDRVLIRLPSDKIKAVSNKARATVGIVAGGGVIEKPLLKAGAN -YWKYKVKAKKW-P-IVRGVAMNVVDHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG------RKE HRKLASPRRGSAGLRPRKRSSELLPTPRTWPQKLL---G-FVGYKVGMTHVFMIDDWPNSPTNGKEIYMPVTVLEVPPII PLALR----AYA----I--DGW--SSSSLQF-------LDITRSKK----------KFDERFKSNLDRIVYFRLLVSTQP RKIPSLGKKAPDLVEIQI---GGGEKKSQLDY-----ALNILGK-EITI-RD-V-FKEGQLIDVVGVTKGKGFAGVIKRY SVVE-LPRWHKHRKGSRK-IGTRGPSLGTPS-----YTPQPGQLGFHRRTEYNKRIIKIGDEPK---------EINPAGG FVRYGIVRNTYVLLEGS-ILGSKKRPIFLRVKKKSDILD-KDGNRI-KEVELPI-IF----SF-PV-RKDLIRRVFIAEF THSLQPKGRDPNAGKRTSAESFGINLGMARVP----------RVKNSGEAA--------------L--AP----NT---- VGGRLAFPPS-VNKKLAEEANVKEKRLAVISALSATADIAFVRARGHVFKDSVRF-P-IVVTDDI---VNL--------- --KTTSLII--VHDSN--S---PIIKAARNLAGVD-V---------------VNAKDVSVIHLAPGAHPGRLTIYTESSI KILDIKMAEST--------LPL------SQNPMRKVKLSKVTVNIGLG----ESGDRLQKAYQLLQELTGAKPVYTISKK TIREFGIRKGQEIGVKVTLRGAQAEEFLRKVLEAIGYRLKK-------SSFDDYGNVSFGIAEHVILPGAR-----YDPE IGIFGMDIAITLE-RAGYRISRRRRKKAKIPKRHR-VTKEEAMEFLRNNFNVQLQIVIL-R--EEIEIPKNVVVD-L--- -K-G--S-IIKIKGPKGEVVKDF-SFAKG--IQISLDG-NK--IVL----E-T-TFANRRKK-AVFYSIVSHIKNMITGV TKGYRYYLKIIYTHFPTSVKVVG-NE--VQITNLIGEKNTRRAQI-L-E-GVKVTVK--G-E-DIVVEG-PNLEAVAQTA ANIESAS------KISGF---DRR-IFSDGIFIYKKEVIVLGSRKGLTPALQHYSVVNVADNSGGKEAMIIGVYG-VLRR VPFANIADMVMVSIKKGTPE-----------VRKQKFRAVIVRQRMPYRRPDGTWISFEDNAVVIIN-PDGT-PKGTEVR GPIAREA--AERWPKIASLATLVV------MVVRREK---KSRKMRGS-RTMGWGIRGQHRDRGSQGGRQIGMHKEK--- -WSWL-VKYGKGWY----GK-HG--FRNISLRKLIKIKEMDGK-KIVDNK---------LLG--GGS-I-S-I-P-VTI- KVGKATNKAIQKVKEMGGEVMH--FSGPAYTRKEYIPGIPQPKITKFTSG----NPNGDYDYEVRLITTEIGQIRHNALE AVRTLTLKTLSKKTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGETLIVIKVKK-- EHLEFAKEALKIASKKLPLRTRIEIKVKPRRRREGKTNYYKRYVYVISKQTRFIVRITNKYVIVQIAKI---DPKGDIMI ASAHSA-ELAKKFGWK----GDE-NNTPAAYLTGYLAGLR--AIKRG-VTECVADIGLHVPSKGNRVFYVIKGAIDAGLK I-PIGDISIENDRIKGEHIAKYAEKLKSENSDLYSKLFSRYLQRGLNPENLPSHFEEILNKILKI-AKAVIRDVPESIRD LYNVCKAIRGMYLNDAKDFLNRVLEEKEALPFWRYNKGASHKSNISAKWKIKAGRYPKKAIRQVLKVLENAEAN----A- TNK--GLDVDKLIIRHIAAHKGITLQRYMPRAFGRATAKYRRTSNIEVILEERIRVRKGDTVRVMRGG------NS-GKE GKVVEVNTKTG--RLA--IEGITRKKVDGT----PV---------------YVWIHASKVM-ITKLDL-------SD--P --RR--------------------REK---LEKSKK--------MPN------------IK-R--------------Y-- ---FLEKSIVKVKIDEYL--AKQYY-----NAEYAGVEVLKTP-I-GTRVIIYAGRPSMIIGRGGRNIKQLAQIFEKVPQ ITITNVEN---PELNARVMAFRLAIALEKGYHFRRAAFISMRRIMNA-GALGAEIIISGKLT-TERARYEKLKEGIVYKS GQQLEKMIDRAIAIAMLKPGIFGVEVVITMVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFE YID----D---G----RWGKITVQLLGR---VNK-------C---GPITPRYPLSYRQMIALPDYVRRYLPSKEIGIIIV STSKGVMSHKEAARLRIGGVALGYVY-MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRL PHGEGRKKWEKWEMRVHKRLIDI-AADERVMRQLMRVRVPEDVYIEIQLGITLEGVIVKYRGTKAAVIERQYLYYDSKYK RYERRRSRIHAHVPPC-INVREGDKVIIGECRPLSKSISFVVLG---KVPPEWKNFKYRGKSIDELLNMPMDEFIKLLPS RQRRSL-KRGFTDAQRHLLEKVRKYRR---EGKFN---KTIKTHVRNLVILPELIGLKMAVYNGKEFVEFTVTP-EMIGH YLGEYSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Sulfolobus_tokodaii_7 Concatenation of 2 sequences VGKKL-------------------LQQR-------------------------------AGRGGINF-RSPSWRRV---- ------G-K--AKIPNIEGKVIDIVHNPGTNAPLALIKLD-DGTKFYVPSVQGLVVGQKIQIGK-N-AA-ISNGNIVEVG NVPEGTIISNIEKTRGDGGKFARSAGTYGVVVGK--TGDKVLVKLSSEKIAQVSSNARAIVGVVAGGGVTEKPLLKAGNN -YWKYKVKAKKW-P-HVRGVAMNAVSHPHGGGLHQS----VSRPSTVSR----NAPPGRKVGH-IAARRTG-------RK HRKLASPRRGSAGVRPRKRASEILPTPRSWPTKLL---G-FVGYKVGMSHIFMIDDKPTSPNYGKEIYVPVSVIETPPVI PLAIR--AYVMG----P--KGE--PTTLTEY------WGD--IDKE----------KMKGKLNNKLNDILYLRVLIATQP KLVPSLGKKKPEIVEVQV-GGGDIKSQLNYVL-----NIL--GK-PLSV-KD-V-FKEGQLIDIIGVTKGKGFQGVVKRY GVVE-LPRWHKHRKGSRK-VGARGPSFSTPS-YV----PQPGQMGYHRRTEYNKRILKISDDPN---------EINPKGG FVNYGIVRNTYLIIEGS-IIGAKKRPLFLRQIKKTHIFD-LKGNKV-EEIELPI-FF----SY-PV-RKDLIRRVFISEF TKALQPKGRDPMAGKRTSALSFGINLGLARVP----------RVKTTGEA---------------AL-AP----NT---- VGGRLAFPPT-VEKKLVEEVNKKEKKLAIISALSATANMNFVKNRGHVFSIDTL--P-IIVVDDI----TKL-------- --TKTKLFV--IHENN--P---VFVKAASNIPGVD-V---------------ILASDLSVIHLAPGGHPGRLTIYTKSSI DVLR------------------MMAETQTVNPMRKLRLEKVTVNIGVG----EAGERLQKAYQLLQELTGVKPVYTIAKR TIREFGVRKGAPIGVKVTLRGKKAEEFLNKVLAAVGHRIKA-------SSFDEYGNVSFGIAEHVLIPGTR-----YDPE IGIFGMDVAITLV-RPGFRVARRRRKKAHIPKRHRTVSKEEAMEFLKQNFNVTIMKAVH-L-YEEIEIPQGINVN-I--- -E-G--M-KIKVKGPKGEIEKDF-SHISG--IEIRKED-NK--IVV----E-T-TFADRRKK-AQFYSIIAHIENMFTGV TKGYRYYLKIIYTHFPVTVKVSG-NE--VQIQNLIGEKNIRRAKI-M-T-GVKVNVK--G-E-DIIVEG-QDIEKVGQTA ANIELAS------KITGY---DRR-VFADGIYIYKKEVIVLGSRKGLTPGLQHYTTVTVADNSGAKEAVIIGIYG-VLRR IPFANIADLVMVSVRKGTPE-----------VRKQKFKAVIVRQRMPFRRPDGTWIAFEDNAVVIVN-PDGT-PKGTEIR GPIAKEA--AERWPKVASIATMVI------MTVRKE----KKSRKYRGYRTHGWGTKGQHRDRGAQGSRQIGMHKEK--- -WSWL-VKYGEGWY----GK-HG--FVNITMRKLIKIKDENGK-KVVDDK---------LIG--SSG-L-K-I-P-LVI- KVNMASKKAIEKVKELGGQIMH--FSGPAYTRKEYIPGVPMPKITKFTMG----NVNGNYDYELRLVALEKGQIRHNALE AARVLALKQLTNKTGSDQNFALIVLKYPHHVIRENKMMAFAGADRLQDGMRLSFGKPIGTAARIERLGDIIMIAKVKK-- EHLEIAKKAFEAAASKIPLKTKIIVRVKYRRRREGKTNYYKRYTYVINNTTRLVVRLTNKYIIAQIAKF---NPKGDVIV VAAHSM-ELAKKFGWK----GDL-NNTPAAYLTGYLLGVR--ALKAG-IKEAVADIGLFVPVKGSRIFTAIKGAIDAGLS I-PVGDLGIKEDRIKGVHIASYAQKLEAENPELFKRLFSKYLERGLHPKDLPSHFEEILNKINKL-AKAVIKNVPASIRD LYNVCKAIRGMKLNDAKQFLNNVLEEKEALPFWKHSHGASHRSNISPKWKVKSGRYPKKAIKYVLKVLENAENN----A- NSK--GLDLENVKIVHIAAHKGIILKRYMPRAFGRSTRKYRYTSHIEVILGERLAIRKGDTVKVMRG-------DKLNFE GKVVEVNRKTG--RIA--IEGLTRKKADGT----PV---------------YRWIHASKVI-ITKLDL-------SD--A --KRKEIIE--RKR--------KAREE---YLKKKE---QTT--M--------------VLVK----------------K Y--FLQRSMTKVMVDEYL--AKQFY-----NAEYAGVEIVKTP-I-GTRVIIYAGRPALIIGKGGKTIKQLAQMLERYPQ ITVTSVEN---PELNARVMAFRLAIALEKGYHFRRAAFITIRRIMNA-GALGAEVIISGKLTS-ERAKYEKLKEGVVYKS GAFLDKIVDRAVAIAMLKPGVYGVEILITMVNLNPLANALTTIYNNEMRRNKQAIIMPASKLIINVLRAMQKEGYIGEFE FID----D---G----RSGKIVVQLLGR---INK-------C---GPIAPRYPLKYKDLLTLPDYVRRYLPSKEIGVLII STNKGVMTHKDAIRERIGGVALGYVY-MPTKARIRLWSTNIENLNFVVNQIKTLAQKTGVEISGPIPLPTSRMEVPVMRL PHGEGKKKWEHWEMKIHKRIIDI-ASDERVMRQLMRVRVPDDVYIEIELGIILEGRLIRYRAEKTGVVERDYLFYDTKYK RYERRRSRIHVHIPPC-LDVKEGDNVIIAECRPIAKSVSFVVIG--KR-PPEWKKFRYRGKSLDELLNMPMDEFIKLLPS RQRRSL-KKGFSDKQRRLLEKIRKYVR---EGKYS---KTIKTHVRDMIILPEMVGLKFAVYNGKEFVEFQVVP-EMIGH YLGEFSITTKKVEHG----EPGLKATR----SSL-FLAMKG- >ARCH_Thermococcus_kodakaraensis_KOD1 Concatenation of 2 sequences M------------------------------------------GKSLIQQR--------RGKGTTTF-RAPSHRYRGAVR YVPLNLV----QE-RTLRGVVEEILHDPGRTAPVARVKFE-DGTKKLIIAPEGVLVGQEIYIGP-E-AP-IAIGNTLPLA KIPEGTYVYDIEGVPGDGGKYVRAGGTYALVVSR--EKDKVIVQLPSGELKAFNPMCRATIGVVAGGGRLEKPIVKAGKA -YYIAKARNRFW-P-KPRGVKMNAVNHPHGGKEHH-----IGRPSTVSR----RAPPGRKVGH-IAARRTG-------RR MGKIHRPRRGSLAYSPRKRAKSIVPRIRSWPKSEVRMLG-FAGYKAGMTHILMIDDSP-GLTKGKEIFVPVTIVEVPPLF VYGIR----AYK-------QGYGLETATEVWFHDLHKNVA--RLPK--NYNEEAFQAKLGQLDLVNDGEIADVRLLVHTQ PWLIG-LKKKPEVMEYAI-----GGDDVKAKFDYAKEKI---GK-ELRA-GE-V-LHEGELLDVIAVTKGKGTQGPVKRW GVKV-QFHKAQRAGKGRH-IGNLGP--WHPA-RVMWTVPQAGQMGFHHRTEFNKRLIAIGENGK-LVLDGNEIEITPKGG FPHYGIVRSDFLMIEGT-IPGSFKRIIRVR--MKVKVFN-LEGEPV-EEIELPK-VF----ST-PF-RPDLIRRAVIASW THRIQPQGRDPQAGK-----------RRVTENI----------GKGHGMAR--------VER---IKTSP-RFAAFVPFA VGGRRTHPPK-VEKIIWEDINKKERRLAIMSAIAATANYDLVRARGHVVDNVVQI-P-LVVTDDL---QKV--------- --FKTALIV--VAKN---E---GIVQGARNHPGVD-V---------------VTVDNLGVEYLAPGTHPGRLTIWTKGAI ERLRMQIN-----------REAILADWE-AHPMRKPRIAKVTINIGVG----ESGERLTKAETMLEQLVGQKPIRRRAKQ TNRDFGIRRGEPIAVKVTLRGEKAYQMLDRLLEAVDRKLKA-------SNFDEHGNFCFGIQEHINIPGVE-----YDPE IGIFGMDVCVTLE-RPGFRVAKRKRQRRKIPTKHK-LTKEEGIVFAMEELKAKVVDAWI-R--EEIEIPEGVEVT-V--- -E-G--N-TVKVKGPKGELQREL-KYP-G--VQIFTED-GK--VVI----Y-K-EFPRKKDV-AIVRTFKAHINNMIKGV TEGFKYRLKVVYSHFPMTVKVQG-DE--VVIENFLGEKNPRRAKI-L-P-GVTVKVK--G-S-EIEVEG-IDKEAVGQTA ANIEQAT------RITKW---DRR-VFQDGIYIVEKAGKRGISPVRPTRALPIGAYLKVADNSGAKVIQIIGVVG-TRRR LAAAGVGDMVVATVKKGRPD-----------MRHQVVRAVVVRQRKEYRRLDGMRVKFEDNAAAIVT-PEGV-PRGTEIR GAIAREA--AERWVRLGSIASIVL-------MIRRRK---KVRKLRGS-HTHGWGCKKKHRGGGSKGGRGMAGTGKRKDQ KWTWT-I--KYAPD--RLGK-RG--FHRINLNDIKDAGIIYEEDGKLVDK---------ILG--TGK-L-T-R-A-LVV- KAYYVTPKAEEKIKAAGGEVMD--VDKPAYTRREYIRGAPGPKITIFDMG----NLSAEFEYEVSLHAEQAMQIRQNALE AIRIQVNRYLQKNVG-RSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARVRK-DQKILTVWVNG-- QHLKFALGAMHRAKMKLPYSAYY-RRVPFRRRREGKTNYHKRLKLLKSKKPRLVVRKTLNHHIAQIVVY---DPKGDKTL VSAHTM-ELMRDFGWK----GHG-GNTPSAYLLGLLIGYK--AKQAG-IEEAILDIGLHPPTRGSSIFAVLKGAVDAGLN VPHSEEIYPEDYRINGEHIANYAKALKEEDEALYRKQFSGYLVKGLEPEKLPEHFEEVKAKIERM-ARASGRDLRISPKH SVELLREIRGMMLNDALRYLDDVIAKKRPVPMKRFNDSQGHKPGK----GFGPGRYPVKVAKAVKKILLNAKNN----A- EQK--GLDVDRLKIIHAAAHRGPVLRGYIPRAFGRATPFNEQTTHIEIVVEENLPIRVGDKVKVMRGD------FK-GVE GKVVEVDLRRY--RIH--VEGVTHKKTDGT-------------------EVFYPLHPSNVM-IVELNL-----------E --DEKREKI---IE------------------RRAA--------LA-------------IE-R--------------Y-- ---FIKEGVKEMLIDEFL--EKELR-----RAGYGGLDIKKTP-L-GTKVTIFAANPGYVIGRGGRRIRELTRILEKQPQ IEVEEIKN---PYLNAKVQAVRLAQALERGIHFRRAAYSAIRAIMRN-GARGVEIRLSGKLTG-ERAKSVRFYQGYLAKV GNPAETLVSRGYAQAQLKLGVIGVKVSIMMTLLDPLANALSHITNSERVGKKEVYIKPASKLIGEVLRVMLENGYIGEFE LID----D---G----RAGIYRVQLIGK---INK-------A---GAIKPRFPVKA---RDYEKWEKRFLPAFEFGILIV STSQGVMTHKEALEKGIGGRLIAYVY--MQKARIKLASTNIKALNEVTDQIKQIAERTGVRMSGPIPLPTKRIRITTRKS PDGEGSATFDRFELRVHKRLVDI-EADERAMRQIMRIRVPEDVTIEIELGRYVEGIVVSDKGKKTVVVERQYYHYLKKYE RYELRKSKVHAHNPEC-INAKVGDKVLIAETRPISKTKSWVVVAVLQRAMARKKEFRYRGYTLDELLNMSLEEFAKLLPS RQRRSL-KRGLSPEQKKLLRKIRLAKK---GKYNK----PIRTHSRDMIVLPEMVGMTIHVYNGKEFVPVEIKE-EMIGH YLGEFAMTRKVVQHG----SPGVGATR----SSM-FVAVK-- >ARCH_Thermococcus_onnurineus_NA1 Concatenation of 2 sequences M----------GKS----------LIQQ----------------------------R--RGKGTTTF-RAPSHRYRGAVR YVPLNLT-K--EK--TLVGKVVEILHDPGRTAPVARVKFE-NGMEKLIIAPEGILVGEEIAIGP-N-AP-IKIGNTLPLA MIPEGSYVYDIEGTPGDGGKYVRAGGVYALVVSR--EKDKVIVQLPSGELKQFNPMCRATIGVVAGGGRLEKPIVKAGKA -YYIAKARNRFW-P-KPRGVKMNAVNHPHGGKEHH-----IGRPSTVSR----RAPPGRKVGH-IAARRTG-------RR MGKIHRPRRGSLAYSPRKRAKSIVPRIRKWPKSEVRMLG-FAGYKAGMTHILMIDDRP-GLTKGKEIFMPVTVVEVPPLF VYGIR----AYR-------QGY--LGLETATEVWFHELNDYVKKTLPKDYNEEAFQAKLGQLDLVNDGEIVDVRLLVHTQ PWLIK-LKKKPEVMEYAI-----GGDDVKAKFDYAKEKI---GK-ELRA--SEV-LHEGELLDVIAVTKGKGTQGPVKRW GIKI-QFHKAQRAGKGRH-VGNLGP--WHPT-RVMWTVPQAGQMGFHHRTEFNKRLIAIGENGKLKLDEKNEIEITPKGG FPHYGIIRSDFLMIQGT-IPGSFKRIIRVR--MKVKVFN-LEGEPV-EEIELPN-VF----AT-PF-RPDLIRRAVIASW THRIQPQGRDPLAGK-----------RRVTENI----------GKGHGMAR--------VER---IKTSP-RFAAFVPFA RGGRRTHPPK-VEKIIWEDINKKERRLAIMSAIAATANYDLVRARGHIVDNVPQV-P-LVVVNDL---EKV--------- --FKTALIV--VAKN---E---GIVQGARNHPGVD-V---------------VTVENLGVELLAPGTHPGRLTIWTKGAI ERLRMQIN-----------REAILADWE-AHPMRKPRIAKVTINIGVG----ESGERLTKAETMLEQLVGQKPIRRHAKQ TNKDFGIRRGEPIAVKVTLRGKKAEEMLRRLLAAVDNKLKA-------SNFDEHGNFCFGIDEHINIPGVE-----YDPE IGIFGMDVCVTLE-RPGFRVAKRKRQRKKIPNRHK-LTKEEGIVFAMEEFNVQVIDAWV-R--EEVEIPEGVEVT-I--- -E-R--N-VVKVRGPKGELEREL-KYP-G--VQIFTED-GK--VVI----Y-K-EFPRKKDI-AIARTFKAHIANMIKGV TEGFTYKLKVVYSHFPMTVKVQG-DE--VVIENFLGEKNPRRAKI-L-P-GVTVKVM--G-S-EVIVEG-IDKEAVGQTA ANIEQAT------RITKW---DRR-VFQDGIYIVEKAGKRGISPVRPTRALPIGAYLKVADNSGAKLIQIIGVVG-TRRR LASAGVGDMVVATVKKGRPD-----------IRHQVVRAVVVRQRKEYRRLDGMRVKFEDNAAAIVT-PEGV-PRGTEIR GAIAREA--AERWVRLGSIASIVL-------MIRRKK---KVRKLRGS-HTHGWGCKKKHRGGGSKGGRGMAGTGKRKNT KWTWT-I--KYAPD--HLGK-RG--FHRINLNEILDIGVAYEEEGKIIDK---------VLG--TGK-L-T-R-P-LVI- KAYYVTPKAEDKIKAAGGEVMD--VDKPAYTRREYIRGAPGPKITIFDMG----NLSAEFQYEVSLHAEQAMQIRQNALE AIRIQVNRYLQKNVG-RSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARVKK-DQKILTVWVNE-- GHLKFALEAMRRAAMKLPYSAYY-RRVPFRRRREGKTNYHKRLALLKSGKPRLVVRKSLNHHIAQIVVY---DPKGDKTI VSAHTR-ELMRDFGWK----GHG-GNTPSAYLLGLLIGYK--AKKAG-IDEAILDIGLHPPTRGSSVFAVLKGAVDAGLN VPHSEEIYPEDYRITGEHIANYAKALKEEDEGKYRKQFSSYLVKGLEPEKLPEHFEEVKARIERM-ARASGRDLRISPKH SVELLREIKGMMLNDALKYLDDVIALKRPVPMRRFNDSQGHKPGK----GFGPGRYPVKVAKAVKKVLLNAKNN----A- EQK--GLDPDRLKIIHAAAHRGPVLRGYIPRAFGRATPFNEQTTHIEIVVEESLPIREGDKVKIMRGD------YK-GKE GKVVEVNLKRY--RIY--VEGVTQKKVDGT-------------------EVFYPVHPSNVM-IVELNL-----------K --DEEREKI---------------------IERRAG--------MA-------------IE-R--------------Y-- ---FIKEGVREMLIDEYL--EKELR-----RAGYGGIDIKKTP-L-GTKVIIFAANPGYVIGRGGRRIRELTRILERQPQ IEVEEIKN---PYLNAKVQAVRLAQALERGVHFRRAAYAAIRAIMRN-GARGVEIRISGKLTG-ERAKSVRFYQGYLAKV GNPAETLVSKGYAQALLKLGVIGVKVSIMMTLLDPLANALSHITNSERVGKKEVYIKPASKLIGEVLRVMQENGYIGEFE FID----D---G----RAGIYRVQLIGK---INK-------A---GAIKPRFPVKA---REYEAWEKRFLPAFEFGILIV STSQGVMTHKEAIEKGIGGRLIAYVY--MQKARIKLASTNIKALNEVTDQIKQIAERTGVRMSGPIPLPTKRIRITTRKS PDGEGTATFDRFELRVHKRLVDI-EADERAMRQIMRIRVPEDVTIEIELGRYFEGIVISDKPKRTVTVERQHYHYLKKYE RYELRRSRIHAHNPPC-INAKPGDKVLIAETRPLSKTKSFVVVGILQRAMARKKEFRYRGYTFEELLNMSLEDFAKLLPA RQRRSL-KRGLSPEQKKLLRKIRLAKK---GKYNK----PIRTHSRDMVILPEMVGMTIHVYNGKEFVPVEIKE-EMIGH YLGEFALTRKIVQHG----SPGVGATR----SSM-FVAIK-- >ARCH_Thermofilum_pendens_Hrk_5 Concatenation of 2 sequences M------------------------------------------GKRLLVQR--------RGRGGSVF-RNPGWKRLGPAR YPPYNPE-E--FKNKVLVGVVKDLLHEPGRGAPLALVEFE-DGTKMYMIPPEGLAVGQKIYYGA-K-AP-AVLGSIVEIG NVPEGTIVSNIEIRPGDGGKLARSSGAYALVLAH--SNGKTLIQLPSKKVKEVSSEARATIGMVAAGGRIEKPMLKAGKM WHWS-RAKSFKY-P-TVRGKAMSAYAHPAGGGHHPK----GLTPAPRNA------PPGRKVGH-IAPRRTG-RKGASRTP MAKGHRPRRGSRAYYPRKRARSIVARVRRWPQNREGFLG-FAGYKVGMLHVIGVEMNKNSPFYGQERFYAATVIEVPPLK VVAVR----VYE----K--TPYGKKTLCEVW------AKD--LLER------VFPLPKDQSYLEEVKSRVSEVRVLAATQ PRLSGLGKKKPELIEIAV----GGPPEKALSL-----ALEKLGK-DLTI--SDV-FKEGDYIDVIAVTKGKGFQGSVKRF GVEE-MPRWHKHRKGHSR-IGSVGP--QKPA--IMFYTPFPGQLGFHQRTEYNKRILKVGDAES-------LKEINPPGG WPHYGLVRSQFIIVEGS-VPGAVKRLVRLREVLEVPVYD-LNGAAV-ERIKLPS-FF-----K-SPVRPDLIRRVYIALF TSRLQPKGTDPLAGL-----------RTTAESL----------GVGHGIARVARI----KGG---LR-AA-RVVQA---- VKGRRAHPPR-VEKIIREEVNRKEKRKALLSALAAVASRDFVLKRGHVVPDIPL--P-VVVADDL---ESI--------- --SKARLIV--VGEA---R---GIELAARNMPGVD-V---------------VTYKELSVLHLAPGGNPGRLTVFTKSAV KGLE---------------MAKVGPVLETDHPMRRVFIGKVVVNIGVG----EGGERLMKAAKLLEELTGQKPSLRPAKK TVREFGVKKGENIGVMVTLRGEKAINFLKKALAAVDYKIHE-------KSIDRHGNVAFGVKEHILIPGVK-----YDPE VGIFGFDVIIAME-RPGYRVARRRRKKSKVPARHR-VTKEETITFLEKILGVQVMRVLQKT--ESVPIPEGVKVH-V--- -N-G--K-RVEVEGPLGKVEKDF-SHARR--ISIRVEG-NS--VVV----E-T--FHAKKDY-ALVGTIASIINNMIIGV TKGYRYKLKIVYAHFPMSLKVEK-DK--IIIENFLGERGKRIAGIMP---GAKVKIE--K-D-DVIVEG-IDLDAVAQTA ANIHLATHLRGKRALSPHGRETGPGI-LDGIYLYAIEHLGVSYRLGLTPGVFMESLVKVADNSGATLAKVIGVPA-VWRR IPGAAVGDIVIVSIRAGKPE-----------LRKQVMRAIVIRQRRPYRRPDGSWIAFEDNAVVIIT-PEGE-PKGTEIR GPLAKEA--AERWPKLSAMASIIV--------MRREK---KSRAY-RGSRTHGWGRVGQHRKSGSRGGRGLVGYHKHK-- -WSWT-V-K-YAPDWY--GK-HG--FTRINVGQLEGDAYVVDL-TQL-NK---------LTG--SGQ-V-R-N-K-IIV- KVPVATKRAISKIEAQGGRVMH--FGTPPYTRLEYIKSNPPVLIPKFDLG----NPKGNFNTVLKLVVMRPGQIRANALE AARQHANKYLTAKVG-EANFFLRVAVFPHHILRENKMMAMAGADRLQDGMRLSFGTPVGRAARVEA-GQIVMLVKVDA-- KNIDHAKEALRRAASKIPLPSRI-IRVPLKRRREGKTNYYKRRKLIISGKPRLVVRVLSRTAIVQIAKA---TPKGDVVI ASAHSN-ELKK-YGWK----GYR-RNTPALYLLGFLAAKK--ALKQG-VTEAIVDIGLHRPVKASRVFAAVKGALDAGLK IPVGDGVLPEDDRVRGEHIANYAKMLKESNPELFKLRFSGYLSAGLDPESLPEHFDSVKQKI-MS-YKLTVETLR----- ------LIKGKSIEEARRILTEIAEMKRSVPLKRYNKKVGHRSDVP-----GPGRYPVKVAKNLLKLLDNLENN----A- EFK--GLNVENLRIVHAAAHKGMKIRNYLPRAFGRATPYYDQLVHVEIIARERIRVRKGDRVLIVRGS------FK-GHE GKVTSVDVKKG--RIH--VEGATLRKADGT-------------------EVPFPIHPSKVV-VTELDL-------SD--P --RRKELVE--RKK----------QVV---VSGQEG--------M--------------ML----------------N-- ---------------EYL--QRQLV-----RANYVHAQFFKTP-I-GTKVIVYAGVPGLVIGRKGANIKAIAEVLEREPQ IDVVEVPN---QDLNAKIMAYRVARALVRGVRFRRAALVALNRIMAA-GARGAEIVISGKLTS-QRHRTEKFTRGYVPKS GEPGEELVDEAIVHVLLKLGMYGVKVRIM-MMLDTLANALSTIMNNEVRGKKQCVIYPSSKLIVAVLDTLKRSGYIGDFE LID----D---G----RGGKIVVNLLGR---INK-------I---GVIKPRYPVKK---NEFEAWEREYLPSRDVGLLIV STPKGVMTHREAKEKGLGGVLLAYVYAVPSKVRIRLSSTNIEDLNAVCEEIRQIAQKTGVKMRGPIPLPVKRMRVVTRRA PSGQGYETFDRFELRIHKRLIDL-DADERATRLLLRTRVPPTVRVEIEVGQVLRLRVEKVKMHNVAVAVHEYLYYNEKYK RYEVRRKKKHVRVPPC-IPVKPGDEVIVAETRPLAKSVSFVVIG--KVGMESTSKFTYRGYTLEELRQMPIEKLAEIMPA RQRRSLLKQGTSEEHLKLLEKIRRAAKLASEGKKQ---PVIKTHLRDFIILPEMVGLTIHVHNGKEFVPVEITP-EKIGH YLGEFALTTKKVEHG----EPGLKATR----SSM-FVALK-- >ARCH_Thermoplasma_acidophilum_DSM_1728 Concatenation of 2 sequences MGKHI-------------------IPQR-------------------------------RGHGSLVY-RSPSHRHI---- ---TEVK-H--VD-QGT-YVIKDIIHAPGRNAPLLELMGS-DGKKAYQIAFTGAFVGQNIVAGN---VDSVSPGTTTVLA NIPDGSYVYNIESSPGDGGEFCRSAGTFALVVSH---GQHVTLKLPSGRMRDFDPRCRATLGVVAASGIKDPPILKAGTH VHYL--RSKAKR-PYTVRGVAMNAVNHPHGGGNHQH----VGRPSTVGR----NAPPGRKVGR-LSPKRRR-----VNGR MATPHHSRRGSMAYYPRVRAKSVDPKIRSWPEGEVKVQG-FAGFKVGMTHVEMIDYRKKSVTAGQPILVPVTVVEVPPLD VVGYR----LYD----E--DAE--GNLVVVF-------EAW--LDK----EIFRKIPEIKKVRDPPESYEDVRIIVATRN KDVPGIPSKKPEIFELRI--GGGNSVKERLEY-----AKNHLGK-QITF--TDF-SKPGKFVDVVSITKGKGFTGHVKRF GVKL-LPRKN---RKHRRMIGTLGP--WHPD-WVRNTVPQAGQMGFQQRTISNVRVIKYGNKEE-------VDSINVRGG FLHYGFVKNDYVLLFGS-IPGASKRLIKMRLNTKVPIYS-VSGEMK-GEIDLPE-VF----DT-EV-REDIIRRAFRAIS LSMRQPYGSSPLAGM--------RRVGHTTRP-------------GLGISRMPRI----AGGSRVVG-IA----SA---- VGGKSAHSPR-TTKNLYVKINDRERKMAKYSAIALTASVEAVKKRGHRFKEGLKL-P-IVVEDGV---EGI--------- --NKTKLIV---ARNS------SAMKAFRSLPGVD-I---------------ASPNSLSIRKLAPGGVGGRLTIFTEGAI ESLK-------------------------MNPMEEVIIDKVVVNIGVG----QAGDRLTKAAKVLEMLTGHKATNTLAKK SIRDFNIRKRLPIGVKVTLRKKDAMEFLQKAFYVKDYKITD-------YSFDKHGNAYFGISDYTDFKGMK-----YDPD IGIFGMDVAIVFRRRGGYRIERRRIGSKTIPNSIR-VRKEEAQDFLQKNFKVTVMINWKEA--RSIKIPDGFKVS-I--- -S-G--T-TVTISYGGKTISKNF-ANN-Y--VKLVEDG-ST--IKI---NA-S--KNNSMVR-GIVGTWASEINNMIKGL KDGFQYEMKIDYSHFPMRVSVKG-KT--VVIENFFGERSPRTAEI-V-G-DTTVTVK--G-D-RVYIAG-ISKKDVGETA ANIERST------IIKGF---DPR-VFQDGIYLISK-GEMKGIAGRQTRGLPLGANITCADNTGARSISLIDVKG-KARR IPAAGVGDMFMASVKKGTPE-----------MRSKVVYAVVIRQKRPYRRPDGTMVQFEDNAAVLVT-PDGE-VRGSEIK GPVAREA--AERWPRIAAIASIIV-------MVRE-----RTKKLRGG--HYGRG-FKAGRGKGKKGGSGNAGMGKHK-- -WIWM-V-K-YDPLHF--GG-KG--FTSINLGDVKRDGFVREENGEIIDK---------LLG--NGN-F-T-V-K-STI- IIDKATEKAISKLSAIGSKI-R--ITGPAYTRKEFMGGVPYPKITTFVQG----NQKKDFPIEMRLVAEEPCQIRHTALE AARVSVNRRMTEAAG-LDYFYLKVVPYPHHVLREHKMATGAGADRISSGMRAAFGRPVGTAARVYP-DDVIMIARTDE-- AHAKELKTALRKAAIKLPTPCKV-VKRKEAGITDYSKRLKL---LKSREK-RFIVRITGKGVIAQVAEY---SDIGDRIL FTVTDK-TLAK-YGVD----LRG-NNIQVCYLVGYIAGIE--SEKNG-VESAVLDTGRRKFRKGGRIAACLKGFTDAGIE VPHGEDVFPDKKRIDGKHLKS------------------------------PVKISEIVKNFGNH-AKARIREADISLKD SVNIAHHLRGMPLSRAKEIIDAVINKTYAIPYFRYLDSVSHRP------GVGPGRYPVKAAKAFKQLLENVENN----A- EFK--GLNTDNLVIKHIAANKGRMIKKYTPKAYGRAGANFKDLINLEIIVTESFPVIMGDVVKVISGS------RK-GEG GKVAEVDHASG--LVV--VEGITIARADGKQKGFGI-QPELDLSRGDRFDKIKSLAARKNI-VVEKPE-----PEPE--P --RKEETAE--AQE--------AKEEA---VAEEKT---EVD--M-----------------K--------------E-R K--FINEAVKRLLVCEYV--VKETE-----NAGFGNMVMKRTP-F-GTNITLYVNRPGLVIGRRGSKVQQMTDTLEKKPQ IEVKDVKD---PDLNPSVIAKKIALSLEKGWSYRKAGNTSLNRTIQA-GAKGVLIKISGKISG-ERARYQKFIYGNVKYS GEPGSKGMITGFSTAKLKVGILGVTVKIL-MKNDTLNDVINSIKNASRLGKREIIAEPAAKLIGKVLKVMQDYNYIKSFE VID----E---S----RGGKFKIVLNTT---INN-------C---GVIKPRFPVKNENLEKYEAR---YLPAEDFGILIL TTTKGVMSNIEARKLGIGGKLLAYVYMVSYKARISLSGTEHRVVDRVCNEIKEIASRTGVEIHGPMPLPTKRLVVPVRKS PDGEGTNTWDHWEMRIHKRLIDV-DADERTLRQLMRIPIPDGVQIEIQIGQVLTGKVVSANMTKSAVVAREYQQYIPKYE RKATKIKKYHVHVPDC-IKIKPGDTVRFAECRKLAKTISFVIVE--KVNSGRAKEFTYKGYSLEDLQKMSMEELIKILPA RARRTL-LREPNYEQKKLMEKLESDEE------------DVKTHVRDVIILPNYVGKIVEVYNGNSYFKFEIKP-EMIGH YLGEFVMTRKEVKHS----GPGVGATR----SSK-FMPLK-- >ARCH_Thermoplasma_volcanium_GSS1 Concatenation of 2 sequences MGKHI-------------------IPQR-------------------------------RGHGSLVY-RSPSHRHV---- ---VDVK-H--LK-PGE-YVVKDIIHAPGRNSPLLELVDS-TGKKVYQIAFTGAYVGQKIVAGN---VDTINPGTTTVLA NIPDGSYVYNIESSPGDGGEFCRSAGTFALVVSH---GSRVTLKLPSGSMRDFDPRCRATVGVVAASGIIDAPILKAGTH VHYL--RSKAKR-PYTVRGVAMNAVNHPHGGGNHQH----VGRPSTVGR----NAPPGRKVGR-LSPKRRK-----VNGS MATPHHSRRGSMAYYPRVRAKSIEPRIRSWPEKVQ---G-FAGFKVGMTHVEMVDYRKTSVTAGQPIFVPVTVIEVPPLD VIGIR--LYDED----E--EGY--EKWTQNL-------DK-ELKEK----------PVPETYD--------VRLIVATRN KDVPGIPSKKPEIFELRI--GGGNSVKERFEY-----ATAHLGK-TIRF--EDF-SKPGKFVDVLSVTKGKGFTGHVQRF GVKL-LPRKN---RKHRRMIGTLG-P-WHPD-WVRNTVPQAGQMGYQQRTISNVRVLKYSKGED-------ADTINVRGG FLHYGLVKNDYVLLFGS-VPGPAKRLIKMRLNTKVPIYS-INGEKR-GEIDLPE-IF----NY-SV-REDLIRKAFRAIS LSLRQPYGSSPLAGL--------RRVGHTTKP-------------GLGISRMPRI----AGGSRVVG-IA----SA---- VGGKSAHSPR-STKKLYVGINEKERKMAKFSAIAMTASADAVRKRGHRFSESLPL-P-VVVEDAV----SGI-------- --KKTKLIV----GTD--S---VSLKVFKSLPGVD-V---------------ASMDSLSIRKLAPGGVGGRLTVYTESAI EKLR-------------------------MNQMQEIIIDKVVVNIGVG----QAGDRLTKAAKVLEMLTGHKPTQTLAKK SVRDFNIRKRLPIGVKVTLRKDDAVNFLNKALYVKDYKIPD-------YSFDKHGNAYFGISDYTDFKGMK-----YDPD IGIFGMDVAIVLKRGGYRIEKRKIGKKTIPSSIR--IKKDEAVEFLEKNFKVSVMIKWEEA--SVIEIPKDVKVG-L--- -S-G--T-MLSMTFGNKKLEKKF-ADN-Y--VRLLVED-NK--IKI---VK-S--KNNSRER-GIVGTWASEISNMVKGL KEGFQYEMKIDYSHFPMRVSVKG-KT--VVIENFFGERSPRTAEI-V-G-ETQVSVK--G-D-RLFLNG-PSKKDVGETA ANIERAT------IIKGF---DPR-VFQDGIYLISK-GEMKGIAGREIRGLPLGANIVCADNTGARSISLIDVKG-KARR IPAAGVGDMFIASVKKGTPE-----------MRSKVVYAVVIRQKRPYRRPDGTMVEFEDNAAVLVT-PDGE-VRGSEIK GPVAREA--AERWPRIAAIASIIV---M--VRE-------RTKKLRGG--HYGRGM-KAGRGKGKKGGRGNAGMGKHK-- -WIWM-V--KYDPL--HFGG-KG--FTSINLGELKADGFVREENGETVDK---------LLG--SGN-F-S-V-K-SRI- IIDKATEKAISKLSAIGSKIMR--ITGPAYTRKEFMGGVPYPKITTFVQG----NQKRDFPIEMQLIAMESCQVRHTALE AARVSVNRRMTEAAG-LDNFYLKVVPYPHHVLREHKMATGAGADRISSGMRAAFGRPVGTAARVYQ-NDVIMIGRTDE-- AHAHELKIALKKAAIKLPTPCKV-VKRKVLGKTDYGRRLRL----LKSKDRRFIVRITNKGIIAQIAEY---SVNGDRIL ATITDK-ALSK-YGIE----LRG-NNLQICYLVGYAAGVE--AQKAG-VETAVLDIGRKKFRKGGRIAACLKGITDSGVD IPHGEDVFPDKKRLNGSHLKN------------------------------PVKLNEAVKNFENN-ARARIVEADISLKD AVNIAHHIRGMKLDYAKQILEDVVSKKYAIPYFRYLDSVSHRP------GKGPGRYPVKAAKVFIDLLSNVENN----A- EFK--GMNTDSLIIKHVAANKGRMIKKYTPKAYGRAGANFKDLINLEVIVTESFPIVKGDVVKVVSGA------RK-GEG GKVAEVDHHSG--LVI--VEGITIAKIDGK-------------------QKGFGISPEKLQ-ITHLDL-----------S --RSERFQK---IK----------ELA---NIKHITIQEEPI--MKER--------------K----------------- ---FVNEAVKRLLVYEYL--VKETE-----NAGFGKMSMKRTP-F-GTNITLYVNRPGLVIGRRGSKVQQMTETLEKKPQ IEVKDVKD---PDLNPSVIAKKIALSLEKGWSYRKAGNTSLKRTIDA-GARGVLIKISGKISG-ERARYQKFIYGNVKYS GEPGSKGMLVGFSTAKLKVGILGVTVKIL-MRNDTLNDVINSIKNASRLGRREIIAEPAAKLIGKVLKVMQDYNYIKSFE VID----E---S----RGGKFKIVLNTT---INN-------C---GVIKPRFPVKNENLEKYESR---YLPAEDFGILIL TTTKGVMSNIEARKLGIGGKLLAYVYMASYKARISLSGTEHKIVDMVCSEIKEIASRTGVEIHGPMPLPTKKLVVPVRKS PDGEGTNTWDHWEMRIHKRLIDV-DADERTLRQLMRIPIPDGVQIEIQIGQVLTGKVISTAMTRSVVVAREYQQYIPKYE RKATKIKKYHVHVPDC-IELRVGDTVRFAECRKLAKTISFVVVE--KVKTGRAKEFSYKGYTLEQLQEMSLEELIKILPA RARRSL-SREMNHDQKKLVEKLEGDYD-------D-----IKTHVRDVIILPSYVGKIVEVYNGNSYSKFEIKP-EMIGH YLGEFVMTRKEVKHS----GPGVGATR----SSK-FMPLK-- >ARCH_Thermoproteus_neutrophilus_V24Sta Concatenation of 2 sequences MGKRI-------------------LVQR-------------------------------RGRGGSQF-RSPSWRREGPVR YPPLGTA----GR-----GYVVDIIHVPGLNAPVAKIRLE-NGLEFLNYAAEGLYVGQEIEIGE-A-AS-PKTGNVVVLG KAPEGTMVFNVEKRPGDGGKFARSGGTYAVVVGQKPEENKTIVRLPSGRTMEVDARGRATVGLVAGGGRIEKPMVKAGKK -YYRARAKAWKY-P-LVRGKAMSPYAHPHGGGSHQK----GGTPVSKTA------PPGQKVGF-IGSRCTG-R-GCVRAR GLKINRPRRGSMGVYPRKRAADIVPRVRTWPEGKPALLG-FAAYKAGMLHAVVVEDRPTSPLYGKEVVRPVTVLDAPPLF IWGFRLYTLDPT-------NGY-RRSIAEVW-------AP--EIRR------VLTLPEKADVVEEFKDVAVDVRALVATQ PHLSGIGKKTPELLEIPI--GGVPSVDERIKF-----AVLL-GK-TVSP--KEV-FTAGQLVDVIAVTKGKGYQGVIKRF GVTI-LPRWHKHRKGHRR-TGTIGP--QAPA--LMFTQPRPGQMGFHQRTEYNKRVVKIGDNGA---------EITPKSG FLHYGVIRGPYILIQGT-VPGAKKRLVVLRPPEKLKVYG-PDGAYI-ADIDPPLHFM-------EPVRPDLIRRAYLSAL SARFQPKGVYEGAGREHSCESFGVGLGIARIP----------RYKGSLWPR---------GC----F-AP----NT---- RGGRRAHPPK-VEKKLHEEINRKEKNLAIRSAIAATAYRSWVAARGHVVDKIPAL-P-LVVVGDA----EK--V------ --GRAKLVV--VSSAD--V---PLAAAVRNFPGVD-V---------------VPVDGLNMLVLAPGGAPGRLTLWTVPAV EKLRPSWKELV---------------LTKGHPMQRIYIEKVVVNIGVG----TGGEKLEKAADLLKELTGAEPSKRRAKR SIKDFGIRKGEPIGVAVTLRRDKAVEFLTKALQAVNNRVKR-------TSFDERGNVCFGIKEHILLPGVK-----YDPA VGIWGMDVCVKLA-KPGLRVQLRRRRRSKVGKRQL-VTREEAIEFFQKILGVQVQVVYA-V--EEVEIPENVKVS-VEKV GPFD--Y-VVKVKGPLGEIAKEF-RNT-P--VAMEVRD-GK--VVL----E-V--YNAKREY-SILGTYKGVLRNMFLGV TKGWRYKLKVIYTHFPMLVKVQG-SQ--LVIENFLGRKSKIVVAI-P-K-GVKVEVK--GKE-DIVIEG-IDRDVVSQLA AAIQSATELRGDERPSPHGREGGLGV-VDGIYVVGYEHVGVPYRFHVTPGIFMNSLVPVADNSGAKLVRVIGVVT-VHRR IPGAGVGDMVVVVVREGKPE-----------LRKQVFRAIVVRQRKPFRRPDGTWVAFEDNAVVIVT-PEGD-PKGSEIH GPVAMEA--TLRWPTIANLASIVV-------MVRRFK---RAVKYRRGSRTHGWGRVGQHRKSGGSGGKGMVGFHKHKWS LVMKYGESGTGWPFYGK----HG--FKQINVGTLLKREGRVKEGGRYVNK---------LLG--GGD-V-D-L-P-IVV- YTPAASRSAVEKIEKAGGEVMR--IKGPPYTREEYIHGAPMIQIPKFDMGTTSAAARAAFPLVAKLVVQERGQIRMQALE AARQMAYKYLSKYVG-DANYYLRLEAVPHHVLRENRMLAMAGADRLQEGMRLAFGSPAGRAARVEA-GQVIFYAEFKP-- EHVAHMKEALRRASTKLPLPTRI-VKVPFRRRREGLTNYRKRRRLILSRKPRLVVRKTNKHIIAQVVVA---KPQGDVTI VGVDTR-ALAK-FGWR----GDE-NNTSAAYLLGLVAGYK--ARLRG-VREAVLDIGLHRPVAGSRVFAVLKGALDAGLE IPHGEEVLPEDDRVSGKHVAEYAAKLKEENPELYKARFSRYLQRGVQPEDLPKHFEEVKKKIEQI-AKAYAPEQKMSWKK SVEVARFIEGMTLRQAKSWLEDVVKMKRPIPIRTFKKKQAHHATPWS--GWPVAKWPVKVARRFLDLLENLENN----A- RFR--GLDVERVVIVHAAAHKGYRIHNIMPRAFGRATRFDEQTVNVEVIAAERLPVRRGDTVLILRGD------FK-GVT GKVVRVDLKRV--RIY--VEGATRTNSKGQ-------------------TVYYPIHPSKVM-IVEADT-----------S --DKVRQKL---------------------LERRKR--------MVPIVGAMS----------AVQRRLPV------Y-K K--ILEENKKKWMIKEFL--EYRLS-----KYGYIDSEILKTP-L-GTRIVIYAERPSRIIGKKGAIVKEISNILMNKPQ IDVIDVSKIEAPEMFPKVVAYRIANAMAKGVRFRRVMFVAVRQLMEA-GAKGFEIVVSGKLST-ERARFEKHTYGKLYKI GYDAKNRVRRAVVHVLLKPGIYGIEVRIAMVMLDLLSNALIQIKNAEAMGKRQVAIWPVNKLIYYTLRVLQRHGYVGEVE YID----D---G----RGGKYVVQLLGK---IND-------I---GPIKPRYPVK---YREIVQWEQKFLPARQIGILVI STNQGVMSHVEAKEKKIGGVLLAYVYASRRKVRIRLYGTNPTDVDQVAREIVDLAKKMGVQVRGPIPLPTRRLMVTVRRA PSGQGYHTFDHWEMRISKRLIDI-EASERVLRRLMTIRVPDTVKIELQLLKLLEVTVEKVRMHKAAVVTHEWVHYIRKYN RYERRRRRIKVRVPEC-IEVKPGDKVIIAETRPLSKTISWVVIGKREDLPEEWGTFRYRGKTLEELLNLPMDEFIKLLPA RQRRSL-KRGLKPEHRKLLEKIRKAKRLAAQGKKV----TIKTHSRDMIILPEMVGLTIHVYNGITYIPVFISP-WHIGH YLGEFALTTKVVQHG----EPGLKATR----SSL-HIAAK-- >BARIO_Bacteroides_fragilis_NCTC_9343 Concatenation of 2 sequences MAVRKFKPTTPGQRHKIIGTFEE-ITAS------------VP-EKSLVYGKKSSGGRNNEGKMTMRY-LGGGHRKV---- IRIVDFK-R--NK-DGVPAVVKTIEYDPNRSARIALLFYA-DGEKRYIIAPNGLQVGATLMSGE-N-AA-PEIGNALPLQ NIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSR--EGKYCVIKLPSGEVRQILSTCKATIGSVGNSDHGLESSGKAGRS -RWQ-----GRR-P-RNRGVVMNPVDHPMGGGEGRA----SGGH-PRSR---KGLYAKGLKTR-APKKQSS-K-YIIERR --------------------------------MP----G-LLGKKIGMTSVFS-ADGK---------NVPCTVIEAGPCV VTQVK----TVE----K--DGY--AAVQLGF-------QD--KTTK----------PLMGHFK----------------- ---AG-VTPKRHLAEFKE---------FENEL-----NL---GD-TVTV--E-L-FDGADYVDVVGTSKGKGFQGVVKRH GFGGVGQSTHGQHNRARK-PGSIGAC-SYPA-KVFKGMRMGGQMGGDRVTVQNLQVLKVIAEHN---------------- ----------LLLIKGS-VPGCKGSIVLIE--MEVNVYN-IKGEDTGRKVTLNESIF----GI-EP-NDHAIYLDVKQFM ANQRQGTHKSKERSE--------IS-GSTRKIG---------RQKGGGGAR--------RGD---MN-SP----VL---- VGGGRVFGPK-P-RDYYFKLNKKVKTLARKSALSYKAQDN----------------A-IVVVEDF----NFE-A------ --PKTKLVV--LPEAN--K---NVYLSARNIEGAN-V---------------QTISGLNTYRVLNAGV----VVLTESSL KAIDASLKKEYAERI----APALKSQFQYSSTMQIPVLKKIVINQGLG-MAVADKKIIEVAINEMTAITGQKAVATISRK DIANFKLRKKMPIGVMVTLRRERMYEFLEKLVRVALPRIRDFKGIET-K-FDGKGNYTLGIQEQIIFPEIN-----IDSI TRILGMNITFVTS-----------------------AQTDEEGYALLKEFGLPFMSRIG-K--LPISIPAGVTVT-L--- -K-D--D-VVTVKGPKGELSQYV--NP-A--INVAIED-GH--ITL----T-E--NENKQKH-AFHGLYRSLVHNMVVGV SEGYKKELELVGVGY--RASNQG-NI--IELA--LGYTHNIFIQL-P-P-EVKVETK--S-EPLILLES-CDKQLLGQVC SKIRSFR------KPEPY---KGKGIKFVGEEIRRKSGK----------MIQVESRLTVCDNSGAKEALCIRVLG-TGRR Y--ASVGDVIVVSVKSVIPS-S-------DVKKGAVSKALIVRTKKEIRRPDGSYIRFDDNACVLLN-NAGE-IRGSRIF GPVARELR-ATN-MKVVSLAPEVLMN-L--SNLKPAEGS-TKTRKRIG-RGPGSGL-GGTSTRGHKGAKSRSGYS-K--- -KIGF-E-GGQMPLQRRVPK-FG--FKNINLETIVGVNDFIEA-GFISVK---------VLG--NGT-L-T-A-K-LSV- EAHAFSKSAVAAIEAAGGNV-R---QQK--GRA---KGNA-QRGNQLAFG----------SFGIKAL--ETKWITGRQIE AARIAVTRYM------QRQGQIWIRIFPDKPITRKPADVRMGKGK---------GSPEGFVAPVTP-GRIIIEA--EG-- VSYEIAKEALRLAAQKLPITTKF-VKIERRIKIKYRVRNKV---SGTAARPRMSVFRSNKQIYVQIIDD---L--SGKTL AAASSL-GMTE---------KLP--KKEVAAKVGEIIAKK--AQEAG-ITTVVFDRNGYLYH--GRVKEVADAARNGGLK F---------------------------------------------------------------M-YFAKLQNVPTSPRK MRLVADMIRGMEVNRALGVLKFS---------------------------------SKEAAARVEKLLRSAIAN----WE QKNERKAESGELFVTKIFVDGGATLKRMRPAPQGRGYRIRKRSNHVTLFVGSKLHIKKGDTVYVNAGE------DK-GKT GRVLKVLVKEG--RAI--VEGINMVSKSTK----PN--AK-NPQ-GGIVKQEAPIHISNLN-PVDPKT-------GK--A --TRVGRKV---SS--------EGLVR---YSKKSG---EEI--MGQKVNPISNRLG--II-RGWDSNWYG------G-N D--YGDSLLEDSKIRKYL--NARLA-----KASVSRIVIERTL-K-LVTITVCTARPGIIIGKGGQEVDKLKEELKKVIQ INIFEVKR---PELDAVIVANNIARQVEGKIAYRRAIKMAIANTMRM-GAEGIKIQISGRLNGAEMARSEMYKEGRTPL- -HTFRADIDYCHAEALTKVGLLGIKVWIC--MTDPIADYLTRLRNAINAKHRVVEV-PASNLKKEITKILFEKGYILNYK FVE----D---G----PQGTIKVALKYD--SVNK-------V---NAIKKLERISSPGMRQYTGYKDMPRVINGLGIAII STSKGVMTNKEAAELKIGGEVLCYVY-MSQKIRIKLKSYDHNLVDKSAEKIVRTVKATGAIVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSFKRLIDIYSSTAKTVDALMKLELPSGVEVEIKVRKERTGVVLSNKMEKTITVAAKFKEKHPIYG KFVSKTKKYHAHDEK--NECNVGDTVRIMETRPLSKTKRWRLVEIIERA------------------------------- -MSRSL-KKGPYINV-KLEKKVLAMNE---SGKKV----VVKTWSRASMISPDFVGHTVAVHNGNKFIPVYVTE-NMVGH KLGEFAPTRTFRGHA------G----N----KKK-------- >BARIO_Bacteroides_fragilis_YCH46 Concatenation of 2 sequences MAVRKFKPTTPGQRHKIIGTFEE-ITAS------------VP-EKSLVYGKKSSGGRNNEGKMTMRY-LGGGHRKV---- IRIVDFK-R--NK-DGVPAVVKTIEYDPNRSARIALLFYA-DGEKRYIIAPNGLQVGATLMSGE-N-AA-PEIGNALPLQ NIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSR--EGKYCVIKLPSGEVRQILSTCKATIGSVGNSDHGLESSGKAGRS -RWQ-----GRR-P-RNRGVVMNPVDHPMGGGEGRA----SGGH-PRSR---KGLYAKGLKTR-APKKQSS-K-YIIERR ---------------------------------MP---G-LLGKKIGMTSVFS-ADGK---------NVPCTVIEAGPCV VTQVK----TVE----K--DGY--AAVQLGF-------QD--KTTK----------PLMGHFK----------------- ---AG-VTPKRHLAEFKE---------FENEL-----NL---GD-TVTV--E-L-FDGADYVDVVGTSKGKGFQGVVKRH GFGGVGQSTHGQHNRARK-PGSIGAC-SYPA-KVFKGMRMGGQMGGDRVTVQNLQVLKVIAEHN---------------- ----------LLLIKGS-VPGCKGSIVLIE--MEVNVYN-IKGEDTGRKVTLNESIF----GI-EP-NDHAIYLDVKQFM ANQRQGTHKSKERSE--------IS-GSTRKIG---------RQKGGGGAR--------RGD---MN-SP----VL---- VGGGRVFGPK-P-RDYYFKLNKKVKTLARKSALSYKAQDN----------------A-IVVVEDF----NFE-A------ --PKTKLVV--LPEAN--K---NVYLSARNIEGAN-V---------------QTISGLNTYRVLNAGV----VVLTESSL KAIDASLKKEYAERI----APALKSQFQYSSTMQIPVLKKIVINQGLG-MAVADKKIIEVAINEMTAITGQKAVATISRK DIANFKLRKKMPIGVMVTLRRERMYEFLEKLVRVALPRIRDFKGIET-K-FDGKGNYTLGIQEQIIFPEIN-----IDSI TRILGMNITFVTS-----------------------AQTDEEGYALLKEFGLPFMSRIG-K--LPISIPAGVTVT-L--- -K-D--D-VVTVKGPKGELSQYV--NP-A--INVAIED-GH--ITL----T-E--NENKQKH-AFHGLYRSLVHNMVVGV SEGYKKELELVGVGY--RASNQG-NI--IELA--LGYTHNIFIQL-P-P-EVKVETK--S-EPLILLES-CDKQLLGQVC SKIRSFR------KPEPY---KGKGIKFVGEEIRRKSGK----------MIQVESRLTVCDNSGAKEALCIRVLG-TGRR Y--ASVGDVIVVSVKSVIPS-S-------DVKKGAVSKALIVRTKKEIRRPDGSYIRFDDNACVLLN-NAGE-IRGSRIF GPVARELR-ATN-MKVVSLAPEVLMN-L--SNLKPAEGS-TKTRKRIG-RGPGSGL-GGTSTRGHKGAKSRSGYS-K--- -KIGF-E-GGQMPLQRRVPK-FG--FKNINLETIVGVNDFIEA-GFISVK---------VLG--NGT-L-T-A-K-LSV- EAHAFSKSAVAAIEAAGGNV-R---QQK--GRA---KGNA-QRGNQLAFG----------SFGIKAL--ETKWITGRQIE AARIAVTRYM------QRQGQIWIRIFPDKPITRKPADVRMGKGK---------GSPEGFVAPVTP-GRIIIEA--EG-- VSYEIAKEALRLAAQKLPITTKF-VKIERRIKIKYRVRNKV---SGTAARPRMSVFRSNKQIYVQIIDD---L--SGKTL AAASSL---GM---------TEKLPKKEVAAKVGEIIAKK--AQEAG-ITTVVFDRNGYLYH--GRVKEVADAARNGGLK F-------------------------------------------------------------KTM-YFAKLQNVPTSPRK MRLVADMIRGMEVNRALGVLKFS---------------------------------SKEAAARVEKLLRSAIAN---WE- QKNERKAESGELFVTKIFVDGGATLKRMRPAPQGRGYRIRKRSNHVTLFVDSKLHIKKGDTVYVNAGE------DK-GKT GRVLKVLVKEG--RAI--VEGINMVSKSTK----PN--AK-NPQ-GGIVKQEAPIHISNLN-PVDPKT-------GK--A --TRVGRKV---SS--------EGLVR---YSKKSG---EEI--MGQKVNPISNRLG--II-RGWDSNWYG------G-N D--YGDSLLEDSKIRKYL--NARLA-----KASVSRIVIERTL-K-LVTITVCTARPGIIIGKGGQEVDKLKEELKKVIQ INIFEVKR---PELDAVIVANNIARQVEGKIAYRRAIKMAIANTMRM-GAEGIKIQISGRLNGAEMARSEMYKEGRTPL- -HTFRADIDYCHAEALTKVGLLGIKVWIC--MTDPIADYLTRLRNAINAKHRVVEV-PASNLKKEITKILFEKGYILNYK FVE----D---G----PQGTIKVALKYD--SVNK-------V---NAIKKLERISSPGMRQYTGYKDMPRVINGLGIAII STSKGVMTNKEAAELKIGGEVLCYVY-MSQKIRIKLKSYDHNLVDKSAEKIVRTVKATGAIVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSFKRLIDIYSSTAKTVDALMKLELPSGVEVEIKVRKERTGVVLSNKMEKTITVAAKFKEKHPIYG KFVSKTKKYHAHDEK--NECNVGDTVRIMETRPLSKTKRWRLVEIIERA------------------------------- -MSRSL-KKGPYINV-KLEKKVLAMNE---SGKKV----VVKTWSRASMISPDFVGHTVAVHNGNKFIPVYVTE-NMVGH KLGEFAPTRTFRGHA------G----N----KKK-------- >BARIO_Bacteroides_thetaiotaomicron_VPI-5482 Concatenation of 2 sequences MAVRKLKPTTPGQRHKIIGTFEE-ITAS------------VP-EKSLVYGKKSSGGRNNEGKMTMRY-IGGGHRKV---- IRIVDFK-R--NK-DGVPAVVKTIEYDPNRSARIALLYYA-DGEKRYIIAPNGLQVGATLMSGE-T-AA-PEIGNTLPLQ NIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSR--EGKYCVIKLPSGEVRQILSTCKATIGSVGNSDHGLERSGKAGRS -RWQ-----GRR-P-RNRGVVMNPVDHPMGGGEGRS----SGGH-PRSR---KGLYAKGLKTR-APKKQSS-K-YIIERR ---------------------------------MP---G-LLGKKIGMTSVFS-ADGK---------NVPCTVIEAGPCV VTQVK----TVE----K--DGY--AAVQLGF-------QD--KTTK----------PLMGHFR----------------- ---AG-VTPKRHLAEFKE---------FETEL-----NL---GD-TITV--E-M-FNDATFVDVVGTSKGKGFQGVVKRH GFGGVGQATHGQHNRARK-PGSIGAC-SYPA-KVFKGMRMGGQLGGDRVTVQNLQVLKVIADHN---------------- ----------LLLIKGS-IPGCKGSIVIIE--MEVNVYN-IKGEDTGRKVTLNESIF----GI-EP-NDHAIYLDVKQFM ANQRQGTHKSKERSE--------IS-GSTRKIG---------RQKGGGGAR--------RGD---MN-SP----VL---- VGGARVFGPK-P-RDYFFKLNKKVKTLARKSALSYKVQNN----------------A-LIVVEDF----VFE-A------ --PKTKLVI--LPEAN--K---NVYLSARNIEGAN-V---------------QTVSGLNTYRVLNAGV----VVLTENSL KAIDASLKKEYADRI----APALKSQFQYSSTMQVPVLKKIVINQGLG-MAVADKKIIEVAINEMTAITGQKAVATISRK DIANFKLRKKMPIGVMVTLRRERMYEFLEKLVRVALPRIRDFKGIES-K-FDGKGNYTLGIQEQIIFPEIN-----IDSI TRILGMNITFVTS-----------------------AETDEEGYALLKEFGLPFMSRIG-K--LPISIPAGVTVT-L--- -K-D--D-VVTVKGPKGELSQYV--NP-A--INVAIED-GH--VTL----T-E--NEKKQKH-AFHGLYRSLVHNMVVGV SEGYKKELELVGVGY--RASNQG-NI--IELA--LGYTHNIFIQL-P-A-EVKVETK--S-EPLIILES-CDKQLLGQVC SKIRSFR------KPEPY---KGKGIKFVGEVIRRKSGK----------MIQVESRLTVCDNSGAKEALCIRVLG-TGRR Y--ASVGDVIVVSVKSVIPS-S-------DVKKGAVSKALIVRTKKEIRRPDGSYIRFDDNACVLLN-NAGE-IRGSRIF GPVARELR-ATN-MKVVSLAPEVLMN-L--SNLKPAEGS-TKTRKRIG-RGAGSGL-GGTSTRGHKGAKSRSGYS-K--- -KVGF-E-GGQMPLQRRVPK-FG--FKNINLDTIVGISDFIEA-GFISVK---------VLG--NGA-L-T-N-K-LEV- EANAFSKSAAAAIEAAGGTV-R---QQK--GRA---KGNA-QRGNQLAFG----------SFGIKAL--ETKWITGRQIE AARIAVTRYM------QRQGQIWIRIFPDKPITRKPADVRMGKGK---------GAPEGFVAPVTP-GRIIIEA--EG-- VSYEIAKEALRLAAQKLPITTKF-VKIERRVKIKYRVRNKI---SGTAERPRMSVFRSNKQIYVQIIDD---L--SGKTL AAASSLGMAEK---------VA---KKEQAAKVGEMIAKK--AQEAG-ITTVVFDRNGYLYH--GRVKEVADAARNGGLK F-------------------------------------------------------------KTM-YFAKLQNVPTSPRK MRLVADMIRGMEVNRALGVLKFS---------------------------------SKEAAARVEKLLRSAIAN---WE- QKNERKAESGELFVTQIFVDGGATLKRMRPAPQGRGYRIRKRSNHVTLFVGAKLHIKKGDTVYVNAGE------DK-GKT GRVLKVLVKEG--RAI--VEGINMVSKSTK----PN--AK-NPQ-GGIVKQEASIHISNLN-PVDPKT-------GK--A --TRIGRRK---SS--------EGLVR---YSKKSG---EEI--MGQKVNPISNRLG--II-RGWDSNWYG------G-N D--YGDSLLEDSKIRKYL--NARLA-----KASVSRIVIERTL-K-LVTITVCTARPGIIIGKGGQEVDKLKEELKKVIQ INIFEVKR---PELDAVIVANNIARQVEGKIAYRRAIKMAIANTMRM-GAEGIKIQISGRLNGAEMARSEMYKEGRTPL- -HTFRADIDYCHAEALTKVGLLGIKVWIC--MTDPIADYLTRLRNAIGAKHRVVEV-PASNLKKEITKILFEKGYILNYK FVE----D---G----PQGTIKVALKYD--SVNK-------V---NAIKKLERVSSPGMRKYTGYKDMPRVINGLGIAII STSKGVMTNKEAAELKIGGEVLCYVY-MSQKIRIKLKSYDHNLVDKSAEKIVRTVKATGAIVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSYKRLIDIYSSTAKTVDALMKLELPSGVEVEIKVRQCIEGIVVSTKMQKTVVIEVERTKKHPKYG KTVQYTKKYKIHDPL--EECSVGDRVLAHETRHFSKTKYFRFYR---KL------------------------------- -MSRSL-KKGPYINV-KLEKRIFAMNE---SGKKV----VVKTWARASMISPDFVGHTVAVHNGNKFIPVYVTE-NMVGH KLGEFAPTRTFRGHA------G----N----KKR-------- >BARIO_Bacteroides_vulgatus_ATCC_8482 Concatenation of 2 sequences MAVRKFKPTTPGQRHKIIGTFEE-ITAS------------VP-EKSLVFGKRSTGGRNNVGKMTMRY-MGGGHKRK---- YRLIDFK-R--NK-DGVPAVVKTIEYDPNRSARIALLFYA-DGEKRYIIAPNGLQVGSTLVSGA-N-AA-PEIGNALPLE NIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSR--EGKYCVIKLPSGEVRQILSACKATIGSVGNSDHGLESSGKAGRT -RWM-----GRR-P-RNRGVVMNPVDHPMGGGEGRA----SGGH-PRSR---TGLYAKGLKTR-APKKQSS-K-YIIERR --------------------------------MP----G-LLGKKIGMTSVFS-ADGK---------NVPCTVIEAGPCV VTQIK----SVE----K--DGY--AAVQVGF-------QD--KTTK----------PLMGHFK----------------- ---AG-VTPKRHLAEFKD---------FETEL-----NL---GD-TITV--E-L-FNDAAYVDVVGTSKGKGFQGVVKRH GFGGVGQTTHGQHNRARK-PGSIGAC-SYPA-KVFKGMRMGGQMGGDRVTTHNLQVLKVIPEHN---------------- ----------LLLIKGS-VPGCKGSIVIIE--MEVNVLN-IKGEDTGRKVTLNESIF----GI-EP-NDHAIYLDVKQFM ANQRQGTHKSKERSE--------IS-GSTRKLG---------RQKGGGGAR--------RGD---IN-SP----VL---- VGGARVFGPK-P-RDYWFKLNKKVKTLARKSALSYKAQEN----------------A-IIIVEDF----TFE-A------ --PKTKLLV--LPEAN--K---NVYLSARNIERAN-V---------------AIASALNTYNVLNAET----LVVTENSL KAIEASLKKEYAERI----APALKNQFQYSSTMQIPVLKKIVINQGLG-MAVADKKIIEVAINELTAITGQKAVATVSRK DIANFKLRKKMPIGVMVTLRRERMYEFLEKLVRVALPRIRDFKGIES-K-FDGRGNYTLGIQEQIIFPEIN-----IDSI TKILGMNITFVTS-----------------------APTDEEGYALLKEFGLPFMSRIG-K--LPISIPTGVTVT-L--- -K-D--N-VVTVKGPKGELSQFV--DP-S--INVAIED-GH--VML----T-E--NENKQRH-AFHGLYRSLVNNMVIGV SEGYKKELELVGVGY--RASNNG-NI--IDFA--LGYTHNIFMQL-P-P-EIKVETK--S-EPLIILES-CDKQLLGQVC SKIRSFR------KPEPY---KGKGIKFVGEEIRRKSGK----------MIQVESRLTVCDNSGAKEALCIRVLG-TKRR Y--ASVGDVIVVSIKSVIPS-S-------DVKKGAVSKALIVRTKKEIRRADGSYIRFDDNACVLLN-NAGE-IRGSRIF GPVARELR-AAN-MKVVSLAPEVLMN-L--SNLKPAEGS-TKTRKRIG-RGPGSGL-GGTSTRGHKGAKSRSGYS-K--- -KIGF-E-GGQMPLQRRVPK-FG--FKNINLETIVGMNDFIEA-GFISVK---------VLG--NGS-L-T-T-K-LDV- EANAFSKSAVAAIEAVGGNA-R---QQK--GSQ---KGNA-QRGNQLAFG----------SFGIKSL--ETKWITGRQIE AARIAVTRYM------QRQGQIWIRIFPDKPITRKPADVRMGKGK---------GAPEGFVAPVTP-GRIIIEA--EG-- VPYEVAKEALRLAAQKLPVTTKF-IKLERRIKIKYRVRNKI---SGTTERPRMSVFRSNKQIYVQVIDD---L--SGRTL AAASSLMEAM--------------PKKEQAAKVGELIAKK--AQEAG-ITTVVFDRNGYLYH--GRIKEVADAARNGGLK F-------------------------------------------------------------KTM-YFAKLQNVPTSPRK MRLVADMIRGMEVNRALGVLKFS---------------------------------SKEASARVEKLLRSAIAN---WE- QKNERKAESGELFVTKIYVDGGATLKRMRPAPQGRGYRIRKRSNHVTLFVDSKLHIKKGDTVYVNSGE------DK-GKT GRVLKVLVKEG--RAL--VEGINMVSKSTK----PN--AK-NPQ-GGIVKQEAAIHISNLN-LVDPKT-------GK--P --TRVGRRE---SS--------DGFVR---YAKKSG---EEI--MGQKVNPISNRLG--II-RGWDSNWYG------G-N D--YGDALLEDSKIRKYL--NARLA-----KASVSRIVIERTL-K-LVTITVCTARPGIIIGKGGQEVDKLKEELKKIIQ INIFEVKR---PELDAVIVANNIARQVEGKIAYRRAIKMAIANTMRM-GAEGIKVLISGRLNGAEMARSEMYKEGRTPL- -HTFRADIDYCHAEALTKVGLLGIKVWIC--MTDPIADYLTRLRNAISAKHRVVEV-PASNLKKEITKILFDKGYILNYK FVE----D---G----PQGTIKVALKYD--SVNK-------V---NAIKKLIRVSTPGLRKYTGYKDMPRVINGLGIAII STSKGVMTNKEAAELKIGGEVLCYVY-MSQKIRIKLKSYDHNLVDKSAEKIVRTVKATGAIVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSYKRLIDIYSSTAKTVDALMKLELPSGVEVEIKVRKERTGVVVSNKMDKTITVAAKFKEKHPIYG KFVSKTKKYHAHDEK--NECNVGDTVHIMETRPLSKTKRWRLVEIIERA------------------------------- -MSRSL-KKGPYINV-KLEKKVLAMNE---SGKKV----VVKTWARASMISPDFVGHTVAVHNGNKFIPVYVTE-NMVGH KLGEFAPTRTFRGHA------G----N----KKK-------- >BARIO_Candidatus_Amoebophilus_asiaticus_5a2 Concatenation of 2 sequences MAVKKIRPLTPGQRFRIAPDFSV-LTKT------------KP-EKSLLLPIKSTGGRNNTGKMTIRY-KGGGHKKR---- MRIIDFK-R--RK-YDIPAVVNSIQYDPMRTAYIALLYYV-DGAKSYIIAPEGLKVGDRVLSGN-N-IA-PEVGNAMPLR TMPTGTIVHNIELHPGRGAAMARSAGTYAQLLAK--EERYVTLKLPSGEMRMVLGECMATVGTVSNSEHNNIVLGKAGRN -RWL-----GRR-P-RVRGVAMNPVDHPMGGGEGKA----SGGH-PRSR---TGLYAKGKKTR-NTNKYSK-N-YILSRK ---------------------------------ML---G-IIGKKLGMTTLYD-EAGR---------SVPCTVITGGPCV VTQIK----NIE----K--DGY--TAVQLGY-------DD--KTVK----------PLMGHFK----------------- ---AQ-TTPKRKLVEFKE-----FGKELGKEI-----QL---GQ-TIQL--HDI-FVEGEYVDAIGLSKGKGFQGVVKRH GFSGVGGKSHGQHNRERA-PGAIGAC-STPS-RVFKGMRMAGRTGGQRVKITNLRIMKLVPEKN---------------- ----------ILVISGS-VPGAKNGYIILE--MELSVLQ-YTGKDTGRKVVLSDTIF----GI-TP-NDHAIYLDVKNIL ANKRQGTHKSKERGE--------IA-GSTKKIK---------KQKGTGTAR--------AGS---IK-SP----IF---- RGGGRVFGPK-P-RDYGFKLNKKLKKLARKSALTYKAQQG----------------N-ISVLEDF----SFE-M------ --PKTKLLI--LPAVD--K---NLVLASRNLPNTS-V---------------ALVEQINTYDLLYSKK----ILISETAL SKLTPRLQHKYFQEV----VPALKNEMNYTSVMQVPRIEKICLNQGVG-AAVQDKKLIEIAVDELTTIAGQKAVPTVARK AISNFKLREGMPIGATVTLRGRKMYEFLDRLITIALPRVRDFRGVND-KSFDGRGNYTLGIKEQIIFPEIS-----IDKI TKLTGMSITFVTN-----------------------TESDKEAHTLLKALGMPFMSRIG-K--LPIKLPQGVTLR-G--- -P-E-ED-IVYVKGPKGELSQYI-D-P-A--ISVTIEN-DT--VTL----H-R--RTNKRHK-ALHGLYRVLINNMIIGV STGFTKSLELVGVGY--KASVQG-NA--LDLD--LGYSHKIYFVI-P-P-EIKVQATKGK-NPLVHLEG-IDKQLLGQVA AKIKTLR------KVEPY---KGKGIRYLGEQIRRKAGK----------MIQQETRLNVADNSGAKQVQCIRVLG-TKKR Y--ASVGDRIVVSVKSASPA-G-------NIKKGAVSKAVVVRTKKEVRRKDGSYIRFDDNAAVLLQ-NNDE-LRGTRIS GPVARELR-EKEFMKVVSLAPEVLME-L--NTLKPAKNS-VKQNTRYG-RGQGSGK-GGTSTRGHKGAKSRSGYK-S--- -KPGF-E-GGQLPLQRRLPM-YG--FKNINLDTIINPEVLHQH-GLVSCK---------ILG--NGL-L-K-T-K-LEV- TAHAFSASASAAIEKLGGKA-K---VQK--GRV---KGLA-HRGSSLAFG----------TFGIKAL--EAIWLTARQIE AARIAMTRAM------KRQGQVWIRVFPDKPITKKPAEVRMGKGK---------GSPEYWAAVVKP-GKILFEI--EG-- VDINLAREATRLAIHKLPIKAKF-VKAKRRLKIRMRIRKRI---QGTAERPRLSVYKSNKATYAQLIND---E--QGYTL VASSSK-SIGV---------QAG-KPIDMARMVGEEIAKQ--AIGKG-IEEVVFDRSGYIYH--GRVKALAEGARAQGLK F--------------------------------------------------------------ME-AVAKLRKSPITPRK MRLVADLIRGVKADKAFAILRNE---------------------------------PKKCAIYLEKLLLAAVAS---WQH KNQDIQLEDAELYIKTIQVDSAGMLKRLQPAPQGRAHRIRKRFNHVTLVVDNKLHIKKGDTVQVLSGN------YR-KKQ GTVLKVFPKTY--RAI--VEGVHIVSKHKK----PT--AK-NPQ-GTIEKVEAPIHISNLM-LIESAT-------SR--P --TRIGRKL---DE--------EGKLQ--RYSKKTG---EFI--MGQKVNPNSLRIG--YI-KGWESNWFS------SKK G--YADKLIEDHKIRKYL--GARMA-----KANLSKIVIERTL-K-RITITVHSSKPGIIIGKGGAEVERIKEELRKLVH VNILEIKR---PELDAKLVGSSMAQQIQARISYKRVVKQALSATMRV-GAQGIKIQVSGRLAGAEIARSEQFKEGRIPL- -HTLRADIDFAISEAQTVYGKIGIKVWIF-MITDPIADYLTRIRNAIRARHRIVEI-PASNLKKAMTELLHEKGYIKQYK FDD----Q--PN----KQGSIKIGLKYN--PGTK-------T---SPINKLERVSKPGLRKYVKASELPSVLNGLGIAIL STSKGIMSDKEARQMKLGGEVLCYIY-MAQKIRIKLKSYDYNLIDKSAEKIVQAVKNTKAVVSGPIPLPSKKEVYTVLRS PHVYKESR-EQFQLSTYKRLIDIYSNSSKTIDALMKLELPSGVEVSIKARKERIGKVISNKGDKTITVLVERKLKHPLYG KFVRRSKKFMAHDAE--NACNEGDRVKIMETRPLSKKKRWRLIEILEKA------------------------------- -MARSI-KKGPYIAH-HLLKKIDAINE---SGSKN----TIKTWSRSSTITPEFVGHTLAVHNGNKFIPVFVTE-NMVGH KLGEFSPTRTFKGHT------K--KNK----NKK-------- >BARIO_Candidatus_Azobacteroides_pseudotrichonymphae_genomovar_CFP2 Concatenation of 2 sequences MGIRKLKPVTPGQRHRIVGMFSE-ITAT------------IP-EKSLVFGKCKSGGRNAEGHRTVRH-IGGGHKRR---- FRLIDFK-R--NK-DGIPARVKSIEYDPNRSARIALLYYA-DGEKVYIVAPNGLKVNQLIVSGK-E-AP-PEVGNSLPLA DIPLGTIIHNIELRPGQGAKMVRSAGVFAQVVSR--EGNYVIVRMPSGETRKVLALCRASIGSVSNSEHALEKSGKAGRI -RWL-----GHC-P-HVRGVAMNPVDHPMGGGEGRA----SGGH-PRSR---KGLYAKGLKTR-NLKKYSS-R-YIIESK --------------------------------MP----G-LIGKKIGMTSIFS-VEGK---------NLPCTVMEVGPCV VTQVK----TVD----K--DGY--EAVQVGF-------ED--KTTK----------PERGHFR----------------- ---AG-VSFKRYLAEFKE----------QGKY-----KE---GD-VITV--D-F-FNKGIYVDVVGISKGKGFQGVVKRH GFRGVGEATLGQSDRQRH-PGSIGAC-SYPA-KVFKGTRMAGQMGNTKVTIQNLEVIELISKYN---------------- ----------LLIVKGS-VPGSKGSILIVK--MEVNIFN-IKGEETGRKVILEDSVF----RV-EP-NDYIVYLDVRRYL ANKRQGTAKSKERSE--------MS-GSTRKLG---------RQKGSGGAR--------RGD---IN-SP----VL---- VGGARVFGPK-P-RDYSFKLNKKEKKMARRSVLSCRMREG----------------G-VIVVEDF----SFE-T------ --PKTKLVI--LPEKD--D---NIFLSARNISKVK-V---------------TTVSNLNTYEILDVNR----LVILESSV VAINANLKKEYQERI----IPALIKEFNYSSVMQVPVLQKIVVNQGLG-DAVVDKKLIDVSIQELTSITGQKAVVTLSKK DISNFKLRRRMPIGVKVTLRRERMYEFLERLMRIALPRIRDFKGIES-K-FDGGGNCTIGIREQIIFPEIN-----IDNI IKIMGMNITFVTS-----------------------AKTNMEGYALLREFSLPFMSRIG-I--LPIVIPERVTVI----- -QKG--N-AIIVKGPEAELYQEI-NHP-V--IRVEIGE-DK--VMV----H-R--LDNKKNC-ALHGLYRSLINNMVIGV SKGYRKELELVGVGY--RVTNTG-NL--LDFA--LGYSHNIYLQL-P-P-EIKVETK--S-ESLIILES-ADKQLLGQVC AKIRSFR------RVEPY---KGKGIRFVGELIRRKSGK----------MIQQESRLIVTDNSGAKEVLCIRVLG-TRRR Y--ASVGDIIVVTVKTVVPS-S-------DIKKGIVSKAIIVRVKKEIRREDGSYIRFDDNACVLLN-STGE-IRGSRIF GPVARELR-TVN-MKIVSLAPEVLMN-L--SSLKPVKGS-TKTCKRVG-RGQGSGC-GGTSTRGHKGQKSRSGYS-K--- -KIGF-E-GGQMPIQRRLPK-FG--FKSVNLSVIIGIDDLVDA-GIVSVK---------ILA--GGI-I-T---SVVEV- TAHAFSEKAEKAILKVGGTV-R---SQK--GRM---KGNA-QRGNRLSFG----------SFGIKTL--QAKWITGQQIE AARIAVTRCM------QRQGQVWVRIFPDKPITKKPAEVRMGKGK---------GSPEGFVVPVTP-GRILFEV--EG-- VVFDVAKEALRLAAQKLPVTTKF-IKGLRRIKIKKRIRKYI---FGTAERPRLTVFRSNRQIYSQLIDD---S--TGNTL VVASSL-GITE-KVS----------KKKIAYRTGVLVAQK--AKEVG-IRSVVFDRNGYLYH--GRVKELADAAREEGLK F-------------------------------------------------------------RTM-YFARLRHIPVSARK VRLVADMIRGIEVFKALGILRFS---------------------------------NKKISLFLEKLLKLAISN----WE QKTGRQAENGELFITMVNVDVSTILKRIRPAPQGRAHRVRKRFSHVVIFVNTKLHIKKGDTVYVNAGD------YK-GKI GCVLKVFLGKQ--RAL--VEGVNIISKTIK----PS--AK-NPQ-GGFEKKEASIHISNLN-VLDPKT-------GK--P --VRIGRKL---GE--------RGLIR---FSKKSG---DEI--MGQKINPISNRLG--II-RGWDSNWCG------G-D N--YGDILYEDSKIRKYL--NTRLA-----KASVSRIVIERTL-K-LVTVVVCTARPGVIIGKGGQEVDKLKEELKRIVQ INIFEIKK---PELDAAIVASNIARQLEAKIAYRHVIKVAIAAAMRM-GAEGIKVQISGRLNGVEIARSEMYKEGRIPL- -HTLRANIDYALSEALTKVGLLGVKVWIC--MTDPIADYLTRLRNAIKAKHKIVEI-PASNLKKEITKILCNKGYIWDYR FIE----D---K----HQGKIKIAMKYS--NINK-------V---NAIKVLKRISKPGLRKYTSYRKMSRVLNGLGIAIL STSKGVMTDKEARDLKIGGEVLCYIYSASHKIRIRLKSYDYNLIDRSAEKIVKAVKSIADDVSGPIPLPTHRRIFTVNRA TFVNKKSR-EQFELASYKRLIDIYASNTKVVDALMKLDLPSGVEVEIKVRKEKIGVVFSNKMDKSVTVAVKWKEKHPIYG KFINKTKKFHVHDEK--SECSVGDIVKIMETRPLSKIKRWRLVKIVSRA------------------------------- -MSRSL-RKGPYINV-KLEKKILLMNE---SKKKS----VVKTWARASMISPDFVGCTIAVHNGNKFIPVYITE-NMVGH KLGEFSPTRQFRGHA------G----N----KKK-------- >BARIO_Chlorobaculum_parvum_NCIB_8327 Concatenation of 2 sequences MAVRKLAPNTPGTRFASYASFEE-ITKS------------EP-EKSLLVPLKKSGGRNTNGRITSRH-MGGGHKRF---- YRLIDFK-R--NK-DNVPAKVAAIEYDPNRSARIALLHYV-DGEKRYILAPKGLKVGDRIESGE-K-VD-IRVGNTMPLK NIPLGTDVHNIEMKAGKGGQMARSAGSYAVLAAR--EGVHATLKLPSGEIRKVRVECRATIGVIGNSEHENISLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPKSP---WGQLAKGQKTR-NKKKAST-K-LIVRGR ---------------------------------MG---A-ILGKKIGMTRLYN-NKRE---------AVPCTVIQAGPCF VAQVK----STE----K--DGY--DAYQLGF-------GE--RVTK----------PLAGHYK----------------- ---AG-KTPGYLLSEVSK-------SLIAGEL-----EA---GA-TVAV--D-V-FTEGEIVDVLGVTKGKGFAGVVKRH NFGG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RTFKGTRMAGRMGGENKTVRNLEIVKVMPESN---------------- ----------LIVVKGA-VPGPKNSYVKIV--MELKVLN-IQGAETGEVVTLNDDIF----AV-EV-SEHAMYLDVKAIL ANRRQGTHKTKTRAE--------VR-GGGKKPY---------RQKGTGNAR--------QGS---SR-SP----IM---- VGGGTIFGPQ-P-RSYEQKVNRKVKQLARRSALSSKAAAG----------------Q-IVVVEDF----SLE-S------ --IKTRLLM--MPHYD--N---VVSTSGRNIEKLN-I---------------QVADQASTYDILNSQA----VLFQKAAL QKIEARLEVYYKETV----VPKMMERFKYENIMMVPRLEKIAVNIGVG-EAAQEPKLLETAMQELGQITGQKPQIRKAKK AISNFKLREGQAIGCRVTLRRKMMYEFLDRFVTVAVPRIRDFRGLSD-TSFDGRGNYNAGIREQIIFPEID-----IDKV PRINGMDISFVTS-----------------------AKTDEEAHELLTLLGMPF---------MPIQLADQAKVE-V--- -K-D--K-MINVTGPKGSLSQAL-VDE----VIVTVED-GA--VTV----Q-R--IDDKRSR-AMHGLYRMLVNNMVEGV TKGFTRKLEMSGVGY--RAELKG-DL--LALT--VGFSHMIYFQA-P-A-EIKIEVP--E-PTVILVSG-IDKALVGQIA AKIRSFR------KPEPY---RGKGIKYEGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--AALGDQIMVTVKAAVPN-G-------VVKKKDVCKAVVVRCAKEQRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DKRYMKIVSLAPEVLMD-L--SSLRPAKGA-VKGRKRVG-RGPGSGN-GTTAGKGNKGQQSRSGYT----- -RPVT-E-GGQMPMYRRLPK-FG--FTPVNLAQIISVLDLKHL-CNASFK---------ILG--NGE-F-E-S-A-VTI- TAHFFSKSAVEKIEKAGGKT-K---TQR--GRM---KGNA-QRGTAVTFG----------SFGLKAL--EPAWITSRQIE AARVAMNRYM------KRDGKIWIRIFPDKPVTKKPAETRMGSGK---------GNPEFWVAVVKP-GRIMFEA--AG-- VPREIAQEAFRLAAKKLPIKTRF-IKAARRQKIKARSRATV---HGNATRPRLCVYRSLSQIYAQLIDD---E--SGKTL MAVSTM-SKDN-AG-L-----QG-SKSERSAAVGKQLAEK--AIAQG-ISNVVFDRNGFRYH--GRIKALADGAREAGLI F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRLVAGLVRGKQVDQAKAILLNS---------------------------------TKSASRNVMVTLKSAVAN---YSQ LNPDERVSDNELFVKAVFVDEGPSLKRTSART-----------DGSCIQDSQKLHVKKNDDVVVIAGN------DK-GKS GKVLKVFPQKG--RVI--VEGVNIRKRHMR----PT--QT-SPQ-GSIIEREFPIHASNVK--------------KS--- --------------------------------------------MGQKVNPTGFRLG--II-KDWTSRWYD------DGP V--IAEKIKQDQVIRNYI--SARLKKE---KAGVSKVVIERTT-K-HIKINIYAARPGAVVGRKGEEINNLSQELTRIVK IDVIEVIK---PEIEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRA-GAEGIRIRCAGRLGGVEIARSEQYKEGKIPL- -HTLRANVDYASVTAHTIAGAIGIKVWVYMPVTDSIADFITRIRNAGSAKNKTTDI-PYTRVRENLSKLLVEKGYIQNYT VIK-TEAD--------KFPFIRVELKYT---ADG-------R---HAIKEISRVSSPGRRVYQGK-DIKRYLGGLGLFIL STSKGILTDKEAREQNVGGEVLFRIYAVQQKIRIKLKSYDHSLVDKWALKIIDVVKQTDAIIFGPIPLPTKTHVYTVNRS PHVDKKSR-EQFAFSSHKRLIEIINPTARTIDMLMKLELPSGVDVEIKSKKSWLGKVVSSSMDKGIVVAVERRVQHPVYK KYFKKTTRLMAHDEK--NEAGVGDVVRVMECRPLSKNKSCRLVEIVEKA------------------------------- -MPRSL-KKGPFIEF-KLEKRILDMNS---KGERK----VVKTWSRSSMISPDFVGHTVAVHNGKTHVPVYVTE-NMVGH KLGEFAPTRLYRGHAGGKAEKG-GSAP----RKK-------- >BARIO_Chlorobium_chlorochromatii_CaD3 Concatenation of 2 sequences MAIRKLAPVTPGSRFMSYPVFDE-ITKS------------KP-EKSLLEPLTKSGGRNSAGRKTSRH-RGGGHKRH---- YRIIDFK-R--NK-DGIVATVAAIEYDPNRSARIALLHYI-DGEKRYILAPKGLKVGDKVESGE-K-VE-IKTGNTMPMK NIPLGTDIHNIEMKAGKGGQIVRSAGAFAVLAAR--EGDYVTLKLPSGEIRKVRVECRATIGVIGNADHENIDLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPKSP---WGQLAKGLKTR-NRKKASQ-K-LIVRGR --------------------------------MGA-----ILGKKIGMTRLFN-EKRE---------AVSCTVIEAGSCF VTQIK----RTD----K--EGY--DAYQVSY-------GE--RVSK----------PLQGHYK----------------- ---AG-VTPGYTLVEFSF-------AELNQEL-----AV---GS-QVSV--E-G-FNVGEKVNVLGVSKGKGFAGVVKRY NFGG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RVFKGTRMAGRKGSANITVKNLEIFKVMPESN---------------- ----------LIVVKGS-IPGPNNSYVKII--MELKVLN-TAGTETGEVVILRDDIF----GI-EI-SEHAMYLDVKSIL ANKRQGTHKAKTRSE--------VR-GGGKKPF---------RQKGTGNAR--------QGS---SR-SP----IH---- VGGGTIFGPQ-P-HTYEQKVNKKVKLLARRSALSAKAQAG----------------K-IVVVDDF----RFD-A------ --IKTKLLL--MPEYD--M---VVNRSGRNIAKLE-I---------------MTADKASTYDILYSNT----LLVQKSAL KTIDARLDTYYREKV----VPALMERFQYKNIMEVPRLQKIAINIGVG-DAAGEPKLLDVAVGELTQIAGQKPQIRKSKK AISNFKLREGQAIGCRVTLRRKAMYEFFDRFVSLAVPRIRDFRGLSD-TSFDGRGNYTAGVKEQIIFPEID-----IDKV PRISGMDISFVTS-----------------------AKSDEEAYVLLSELGMPFMSRIG-K--MPIPLSNQAKIE-I--- -N-D-S--IIRVSGPKGSLEQKL--TD-Q--VIITEEN-SA--LLV----R-R--IDDKKAR-AQHGLYRMLINNMVQGV TNGFTTKLEIAGVGF--RAEMKG-EL--LALT--LGFSHLIYFKA-P-E-GIKLETP--D-QVTVLISG-IDKALVGQVA AKIRSFK------KPEPY---RGKGIKYSGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--ASLGDQVIVSVKTAVPG-G-------IVKKKDVCKAVVVRAVKESRRKDGSYIRFDENAVVILN-AQGE-PRGTRIF GPVARELR-DKRYMKIVSLAPEVLMN-L--SSLRPAKGS-VRNKKRVG-RGQGSGN-GTTAGKGNKGQQARSGYK----- -RPII-E-GGQVPVYRRLPK-FG--FTSINLLQILTVQDFKTL-LHASFK---------VLG--AGE-V-T-Q-P-ITI- TAHFFSKSAEEKIAAAGGKT-K---TQR--GRM---KGNA-GRGTSVAFG----------SFGLKAM--EPAWITSRQIE AARIAMTRYM------KRDGKVWIRIFPDKPVTQKPAETRMGSGK---------GSPEFWVAVVKP-GRVMFEA--DG-- VSKEIATEAFRLAAKKLPIKTKF-IKAARRQKIKDRSRVSV---QGTASKPRLCIYRSLAEMYAQLIDD---V--NGKTL VTASTM-TKNN-KAFE------G-TKSDASRIVGQQIAEK--ALAAG-ITNVVFDRNGFRYH--GRVKALADGAREAGLI F--------------------------------------------------------------ME-AKAVLRNTPTSPRK MRLVAGLVRGKQVNQAKAILLNS---------------------------------TKAASKNVMLTLKSAVSN---YTL NNPDERVSDQELFVKAIFVDGGMTLKRTLPAPMGRAYRIRKRSNHLTIVVDKKLHVKKNDTVTVISGN------DK-GKM GKVLKVFPVAS--RVI--VEGVNIRKRHMR----PL--QG-QTQ-GRIIEREFPIHSSNVK--------------KS--- --------------------------------------------MGQKVNPTGFRLG--II-RDWTSRWYD------DSP V--ISEKIKQDHIIRNYV--LARLKKE---RAGIARINIERTT-K-HVKINIYAARPGAVVGRKGEEINNLSQELSRIVK IDVVEVIK---PEIEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRA-GAEGVRIRCAGRLGGAEIARAEQYKEGKIPL- -HTIRANVDYASVTAHTIAGTIGIKVWVYMPVTDSIADYITRIRNAGRAKNSTTDI-PYSKLKENISQLLLEKGYIKNFT VIT----T---E----KFPFLRIDLKYM---QSG-------E---PAIKELTRVSKPGRRVYDGK-DIKKYLGGLGLYVL SSSKGVITDKEARAQGVGGEILFRIYAVQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKSHVYTVNRS PHVDKKSR-EQFSFSSHKRLIEIMNPTSRTIDMLMKLELPSGVDVEIKSKKSWTGKVVSDKMDKACVIAVERRVQHPVYK KYFKKTTRLMVHDEN--NEAGVGDLVRVVECRPLSKRKSCRLAEIVEKA------------------------------- -MPRSL-KKGPFIDI-KLEKRILEMNS---KGEKK----VVKTWSRSSMISPDFVGHTVAVHNGKSHVPVYVGD-NMVGH KLGEFAPTRNYRGHAGGKSEKG-GSAP----RKK-------- >BARIO_Chlorobium_limicola_DSM_245 Concatenation of 2 sequences MSYPG---------------FDE-ITKS------------EP-EKSLLVPIKKSGGRNSAGRKTSRH-RGGGHKRH---- YRIVDFK-R--NK-DGIPALVASIEYDPNRSSRIALLHYN-DGEKRYILAPKGLNVGDKVESGE-K-VE-IKAGNTMPLK NIPLGTDIHNVEMKAGKGGQIVRSAGAFAVLAAR--EGDYATLRLPSGEIRKVRVECRATIGVVGNSDHENVVLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPKSP---WGQLAKGLKTR-NKKKAST-K-LIVRGR --------------------------------MGA-----ILGKKIGMTRLYN-DKRE---------AISCTVIQAGPCF VTQVK----SAE----K--DGY--DAYQIGI-------GE--RINK----------PMQGHYK----------------- ---AG-VTPGFMMAEFKK-------TEFSENL-----EA---GN-PVSV--E-S-FKEGEKVNVLGVSKGKGFAGVVKRH NFGG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RTFRGTRMAGRMGGDNITVKNLEIVKIMPESN---------------- ----------LLVIKGA-VPGPKNSYVKIV--MELKVLN-TGGTETGEVVTLNDEIF----GA-DI-SEHAMYLDVKSIL ANRRQGTHKAKTRAE--------VR-GGGRKPF---------RQKGTGNAR--------QGS---TR-SP----LM---- IGGGTIFGPQ-P-RSYDQKVNKKVKQLARRSALSAKAQAG----------------Q-IVVVEDF----RLG-E------ --IKTKLML--TPEYD--M---IIARSGRNIEALN-I---------------MSAEKASTYDILDSQA----IVFQKAAL KKIEARLEIFYKDKV----VPKLMERFQYKNVMMVPKLQKIAINIGVG-EAAAEPKLLETAMSELAQITGQKPQIRKSRK AISNFKLRENQPIGCRVTLRRKTMYEFLDRFVSLAVPRIRDFRGLND-TSFDGRGNYTTGIREQIIFPEID-----IDKV PRISGMDISFVTS-----------------------AATDEEAYVLLAELGMPFMSRIG-K--MPISLSNQAKIE-I--- -S-D--A-NVKVTGPKGTLEQAL--VA-Q--VTLQEEN-GV--VTV------QRVDETKKSK-AMHGLYRMLISNMVEGV TKGFTRKLEIAGVGY--RAELKN-DL--LALT--LGYSHMIYFKA-P-D-SIKIEVP--D-QTTILISG-IDKALVGQVA AKIRSFR------KPEPY---RGKGIKYEGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--AGLGDQVIVSVKAAVPG-G-------VVKKKDVCKAVVVRCAKEQRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DRKYMKIVSLAPEVLMD-L--SSLRPAKGA-VKSKKRVG-RGQGSGN-GTTAGKGNKGQQARSGYK----- -TPIN-E-GGQIPIYRRLPK-FG--FTPVNLEQIISVLDLKAL-CNASFK---------ILG--SGE-L-T-K-A-LKI- TAHFFSKSAEEKIIKAGGEV-K---SQR--GRM---KGNS-GRGTSVSFG----------SFGLKAM--EPAWITSRQIE AARVAMNRYM------KRDGKIWIRIFPDKPVSKKAAETRMGSGK---------GSPEFWVAVVKP-GRIMFEA--EG-- VSREVATEAFRLAAQKLPIKTKF-IKASRRQKIKDRSRKQV---HGNEKKPRLCVYRSLSQIYAQLIDD---D--NGKTI MSVSSM-SKEN-RA-L-----EG-TKCDVCRIVGLQLGEK--AKAQG-ITKVIFDRNGFRYH--GRVKALADGAREAGLV F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRLLAGLVRGKPVDQAKAILLNS---------------------------------TKGASRNVMLTLKSAVAN---YAQ LNPDERVSDQELVVKEVFVDQGATLKRMLPAPMGRAYRVRKRSNHLTVIVDKKLHVKKNDSVVVISGN------DK-GKA GKVLRVYPQKG--RVI--IEGVNIRKRHMK----PT--QS-HPQ-GSIIEREFPIHASNVK--------------KS--- --------------------------------------------MGQKVNPTGFRLG--II-KDWTSRWYD------D-S P-VISEKIKQDHVIRNYV--LARLKRE---KAGIARIVIERTT-K-HVKINIYAARPGAVVGRKGEEINNLSQELTRIVK IDVVEVIK---PEIEAQLIGDNIAYQLENRVSFRRAMKQAIQQAMRA-GAEGIRIRCAGRLGGAEIARAEQYKEGKIPL- -HTIRANIDYASVTAHTIAGTIGIKVWVYMPVTDSIADYITRIRNAGRAKNKTTDI-PYSKLRENISELLVAKGYIKSFT VIT----T---E----QFPFIRIDLKYS---ALG-------E---PAIREITRVSKPGRRVYQGK-DIRKYLGGLGLYIL SSSKGIITDKEAREQGVGGEILFRIYAVQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKAHIYTVNRS PHVDKKSR-EQFSFSSHKRLIEIINPTTRTIDMLMKLELPSGVDVEIKSKKSWQGKVVSDKMDKAILVTVERRVQHPVYK KYFKKTTKLMVHDEK--NEAGVGDLVKVVECRPLSKKKSCRLVEIIEKA------------------------------- -MPRSL-KKGPFIDF-KLEKRILDLNA---KDEKK----VVKTWSRSSMISPDFVGHTIAVHNGKTHVPVYVSD-NMVGH KLGEFAPTRTFRGHAGGKAEKG-GSAP----RKK-------- >BARIO_Chlorobium_phaeobacteroides_BS1 Concatenation of 2 sequences MAIRKLGPVTPASRYLSYSKFEE-VTKS------------TP-EKSLLAPLKKSGGRNRAGRITSRH-KGGGHKRF---- YRIIDFK-R--SK-DNIPAKVAAIEYDPNRSSRIALLHYA-DGEKRYILAPKGLKVGDVLHSGD-K-VD-IKVGNSMPLK NIPLGADVHNIELKQGKGGQMARSAGAFATLAAK--EGDHATLKLPSGEIRKVRIECRATIGGIGNDDHENIVLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGRS-KSGGGRKHPKSP---WGQLAKGLKTR-NKKKASS-K-LIVRGR --------------------------------MAA-----ILGKKIGMTSIYN-ANRE---------AEPCTVIQAGPCF VSQVK----TTE----N--DGY--EAYQLSI-------GE--RVSK----------PLRGHFK----------------- ---AG-IAPGYKVVEFGK-------DDMGLDL-----EQ---GS-AVSV--E-I-FSAGDAVEVQGVSKGKGFAGVVKRH NFSG-GQRTHGQSDRLRA-PGSVGGA-SDPS-RTFKGTKMGGRMGGKTVKVKGLEIVKVIPESN---------------- ----------LLVIKGS-VPGVKNSYVQIV--MELKVLN-TGGSETGEVVTLNDAVF----SA-EV-SEHAMYLDVKSIM ANRRQGTHKAKNRSE--------VR-GGGRKPY---------RQKGTGHAR--------QGS---TR-SP----LM---- TGGGTIFGPE-P-RDYGLKVNKKVKKLARRSALTNKANEG----------------G-IVVVEDF----VFD-Q------ --IKTRLML--MPEHN--D---IIVRSGRNIPKLQ-V---------------VVADNASTYDILDSQT----VLVQKTAL KKIEARLENTYKDKV----VPALMERFKYKNIMMVPRLTKISVNIGVG-EAAAEPKLLETAIQELSQITGQKPQIRKARK AISNFKLREGQAIGCRVTMRKKYMYEFLERFVTLAVPRIRDFRGLST-TSFDGRGNYSVGVREQIIFPEID-----IDKV PRIQGMDISFVTT-----------------------AKTDEEAFALLSELGMPFMSRIG-K--MPIKLAEQAKIE-I--- -K-D--N-VISVSGPKGNLEQRL--VP-E--VTVDIAD-GQ--VAV------TRIDDSKRSR-AMHGLYRMLISNMLEGV TSGFSKKLLINGVGF--RAEKKA-EF--LALT--LGYSHMIYFKA-P-E-EIAIECP--D-PTSIVVSG-IDKALVGQVA AKIRSFR------KPEPY---RGKGIRYSDEFVRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--ASLGDQIMVTVKAAVPG-G-------VVKKKEVTKAVVVRCAKEKRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DKKYMKIVSLAPEVLMD-L--SSLRPAKGA-VKNKKRIG-RGPGSGN-GTTAGKGNKGQQSRSGYT----- -RPVS-E-GGQMPIYRRLPK-FG--FTKVNLSQIITVENLKSL-CSARFK---------ILG--NGE-L-K-S-P-VTI- TAHFVSKSAQEKILQAGGTI-K---VQR--GRM---KGDA-QRGTTISFG----------SYGLKAL--EPAWITNRQIE AARIAMNRYM------KRDGKIWIRIFPDKPVTKKAAETRMGSGK---------GSPEFWVSVVKP-GRIMFEA--DG-- VPLDVATEAFRLAAKKLPIKTKF-IKVARRHKIKTRSKARG---QGTVEKPRLCVFRSLSQIYVQLVDD---V--NGAIL LSVSSM-SKEN-KG------LKG-TKCDISRTIGKQIGEK--AVQKG-ITKVVFDRNGFRYH--GRVQALADGAREAGLV F--------------------------------------------------------------MQ-AKAVLRHTPTSPRK MRIVAGLIRGKQVDQAKAILMNS---------------------------------TKAASRNVMQTLKSAVAN---YSQ KNPDTRAGDNDLFIKEIFVDEGPTIKRMLPAPMGRAYRIRKRSNHLTIIVDTKLHVRKNDTVLVIAGN------DK-GKT GKVLRVFPQKN--RVI--VEGVNIRKRHVR----PT--QS-HPQ-GAIIEREFPIHASNVK--------------KS--- --------------------------------------------MGQKVHPTGFRLG--II-KDWTSRWYD------DGP V--IAEKIKQDQVIRNYV--NTRLKKE---RAGVARIVIERTT-K-HIKINIFAARPGAVVGRKGEEINNLSQELNRIVK IDVVEVVK---PEVEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRA-GAEGIRIRCAGRLGGVEIARSEQYKEGKIPL- -HTIRANVDYASVTAHTIAGAIGIKVWVYMPVTDSIADYITRIRNAGNASNKTTDI-PYSRLKENLSRLLVEKGYIKSYT VIT----S---E----QFPFIRIDLKYT---DSG-------K---PAIKEITRVSKPGRRTYEGK-DLKKYLGGLGLFIL STSRGVLTDKEAREQGIGGEVLFRILAVQQKIRIKLKSYDHSLVDKWAVKIIDVVKQTDAIIFGPIPLPTKTHVYTVNRS PHVDKKSR-EQFSFSSHKRLIEII-PTGRTIDMLMKLELPSGVDVEIKSKKSWVGKVVSDKMDKAIVIAIERRVQHPVYK KYFKKTTRLMAHDEN--NDAGIGDIVKVTECRPLSKRKSCRLVEVVEKA------------------------------- -MPRSL-KKGPFIES-KLEKRIAALNS---KDEKK----VVKTWSRSSMIAPEFVGHTIAVHNGKSHIPVYVSE-NMVGH KLGEFAPTRTYRGHA------G---GK----SEKGGSAPRKK >BARIO_Chlorobium_phaeobacteroides_DSM_266 Concatenation of 2 sequences MSYPG---------------FDE-ITKS------------EP-EKSLLVPVKRTGGRNRAGRITSRH-MGGGHKRH---- YRIIDFK-R--NK-DGVPATVASIEYDPNRSSRIALLHYN-DGEKRYILAPKGLKVGEKVESGE-K-VE-IKTGNTMPLK NIPLGTDIHNVEMRAGKGGQIVRSAGAFAVLAAR--EGDYVTLKLPSGEIRKVRVECRATIGVVGNAEHENIVLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRRHPKSP---WGQLAKGLKTR-NKKKASQ-K-LIVRGR --------------------------------MGA-----ILGKKIGMTRLYN-DKRE---------AISCTIIQAGPCF VTQVK----HAE----K--DGY--DAYQIGI-------GE--RVNK----------PMLGHYK----------------- ---AG-VTPGYKIAEFSK-------SEINLEL-----EA---GA-PLDL--S-V-FKEGEKINVLGVSKGKGFAGVVKRH NFGG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RTFRGTRMAGRMGGCNITVKNLEIIRIMPESN---------------- ----------LLVVKGA-IPGPKNSYVKIV--MELKVLN-TSGTETGEVVTLNEEIF----GV-EV-SEHAMYLDVKSIL ANKRQGTHKAKTRAQ--------VR-GGGRKPY---------RQKGTGNAR--------QGS---TR-SP----LM---- IGGGTIFGPQ-P-RSYDQKVNKKVKLLARRSALSAKAKAG----------------K-ILVIEDF----RLD-A------ --IKTKLML--TPEYD--M---IIARSGRNIPVLN-I---------------MTADKVSTYDILNSSA----ILFQKTAL TKIEARLESFYREKV----VPVMMERFQYSNVMMVPKLEKISINIGVG-EAAAEPKLLETAMLELGQITGQKPQVRKSRK AISNFKLRENQAIGCRVTLRRKKMYEFLDRFVSLAVPRIRDFRGLSN-TSFDGRGNYTAGIREQIIFPEID-----IDKV PRICGMDISFVTS-----------------------AATDEEAYVLLAELGMPFMSRIG-K--MPIPLSNQAKIE-I--- -T-D-T--DLTVTGPKGKLHQAL--TP-Q--VIITQED-GV--VTV----Q-R--IDDKKAK-AMHGLYRVLISNMVEGV TNGFTRKLEIAGVGY--RAELKN-DF--LALT--LGYSHMIYFKA-P-D-EITIQVP--D-QTTILVTG-IDKALVGQVA AKIRSFR------KPEPY---RGKGIKYEGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--AALGDQIIVSIKAAVPG-G-------VVKKKDVCKAVVVRCVKEQRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DRKYMKIVSLAPEVLMD-L--SSLRPAAGA-VKNKKRVG-RGQGSGN-GTTAGKGNKGQQARSGYQ----- -KPIN-E-GGQVPVYRRLPK-FG--FTSLNLSQLISVYDLKAL-CSGSFK---------ILG--NGE-I-T-T-A-IKI- TAHFFSKSAEEKIIKAGGQV-K---TMR--GRM---KGNS-GRGTSVDFG----------SFGLKAL--EPAWITSRQIE AARVAMTRFM------KRDGKIWIRIFPDKPVTKKAAETRMGSGK---------GSPEFWVAVVKP-GRIMFEA--DG-- VPREVATEAFRLAAQKLPIKTKF-IKASRRQKIKDRSRVKV---HGTMAKPRLCVYRSLSQIYAQLIDD---D--NGKTI MAVSSM-SKEN-KALE-----G--TKSEVCTVVGKQLAEM--ALAKG-ITTVVFDRNGFRYH--GRLKALAEGAREAGLV F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRLVAGLVRGKQVDLAKAILLNS---------------------------------TKSASRNVMMTLKSAVSN---YAL INPDERVSDQELFIKAVYVDQGATLKRTLPAPMGRAFRIRKRSNHLTIIVDKKLHVKKNDMVVVISGN------DK-GKT GKILRVFPVKG--RVI--VEGVNIRKRHMK----PT--QG-NPQ-GSIIEREFAIHASNVK--------------KS--- --------------------------------------------MGQKVNPNGFRLG--II-RDWTSRWYD------DSP V--IAEKIKQDHVIRNYV--QARLKRE---KAGIARIVIERTT-K-HIKINIYAARPGAVVGRKGEEINNLSQELSRIVK IDVVEVIK---PETEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRA-GAEGIRIRCAGRLGGAEIARAEQYKEGKIPL- -HTIRANVDYASVTAHTIAGTIGIKVWVYMPVTDSIADFITRIRNAGRARNKTTDI-PYSKLRENMSQLLLEKGYIKNFT VIT----T---E----KFPIIRVDLKYG---ATG-------E---SAIKEITRVSKPGRRVYDGK-DIKKYLGGLGLYIL SSSKGIITDKEARAQGVGGEVLFRIYAAQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKAHVYTVNRS PHVDKKSR-EQFSFSSHKRLIEIINPTSRTIDMLMKLELPSGVDVEIKSKKSWQGKVVSDKMDKAIIVVVERRVQHPVYK KYFKKTTRLMAHDEK--NEAGIGDLVKVVECRPLSKRKSCRLVEIIEKA------------------------------- -MPRSL-KKGPFIDF-KLEQRILDMNS---KGEKK----VLKTWSRSSMISPDFVGHTIAVHNGKTHVPVYVGD-NMVGH KLGEFAPTRTFRGHAGGKAEKG-GSAP----KKK-------- >BARIO_Chlorobium_tepidum_TLS Concatenation of 2 sequences MAIRKLAPVTPGTRFASYAGFDE-ITKS------------TP-EKSLLVPIKRTGGRNSTGRVTSRH-MGGGHKRF---- YRIIDFK-R--NK-DNVPAKVAAIEYDPNRSARIALLHYV-DGEKRYILAPKNLKVGDRIESGE-K-VD-IKVGNTMPLK NIPIGSDVHNIELKIGKGGQIARSAGAYAVLAAR--EGNYATLKMPSGEIRKVRIECRATIGVIGNAEHENISLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPKSP---WGQLAKGLKTR-NKKKAST-K-LIVRGR ----------------------------------M---GAILGKKIGMTRLYN-DKRE---------AVPCTVIQAGPCY VTQVK----STE----K--DGY--EAYQLGF-------GE--RVSK----------PLAGHYK----------------- ---AG-KNPGYILSEVSK-------SLIVGEL-----EA---GA-TVPV--D-V-FKEGDKVNVLGVTKGKGFAGVVKRH NFGG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RTFKGTRMAGRMGGKNKTVQNLVIVKVMPESN---------------- ----------LIVVKGA-VPGPKNSYVKIV--MELKVLN-IQGAETGEVVTLNDEIF----AV-EV-SEHAMYLDVKAIL ANRRQGTHKAKTRAE--------VR-GGGKKPF---------RQKGTGNAR--------QGS---TR-SG----LM---- VGGGAIFGPQ-P-RTYDQKVNRKVKQLARRSALSAKAAAG----------------Q-IVVVDDF----SFE-A------ --IKTRLLM--MPHHD--N---VVSTSGRNIEKLN-V---------------MVADQASTYDILNSQV----VLFQKGAL QKIEARLEVYYRETV----VPKLMERFKYKSIMMVPRLEKISVNIGVG-EAAQEPKLLETAMQELGQITGQKPQVRKAKK AISNFKLREGQAIGCRVTLRRKIMFEFMDRFISVAVPRIRDFRGLSD-TSFDGRGNYNVGIREQIIFPEID-----IDKV PRINGMDISFVTS-----------------------AKTDEEAYELLSLLGMPFMSRIG-K--MPIRLADQAQVE-V--- -K-E--N-MINVTGPKGALSQAL--VD-E--VIVSVAD-GA--VTV---QR-K--DDSKRAR-AMHGLYRMLVSNMVEGV TKGFTRKLEMSGVGY--RAELKG-NL--LALT--LGYSHMIYFQP-P-A-EIKIEVP--D-PTTVLVSG-IDKALVGQIA AKIRSFR------KPEPY---RGKGIKYEGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--AALGDQIMVSVKAAVPG-G-------VVKKKDVCKAVVVRCVKEQKRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DKRYMKIVSLAPEVLMD-L--SSLRPAKGA-VKARKRVG-RGPGSGN-GTTAGKGNKGQQSRSGYQ----- -RPVI-E-GGQMPIYRRLPK-FG--FTPVNVAQIISVLDLKHL-CNASFK---------VLG--NGE-L-T-S-T-VTI- TAHFFSKSAEEKIAKAGGKI-K---TQR--GRM---KGNA-QRGTAVTFG----------SFGLKAM--EPAWITSRQIE AARIAMNRYM------KRDGKIWIRIFPDKPVSKKPAETRMGSGK---------GSPEFWVAVVKP-GRVMFEA--DG-- VPREVAVEAFRLAAKKLPIKTKF-IKTARRQKIKARSRAVV---RGTQERPRLCVFRSLSQIYAQLIDD---E--SGKTL MAASSM-SKEN-AG------LTG-TKSEVSAAIGKQIAEK--ALAQG-ISRVVFDRNGFRYH--GRIKALADGAREAGLI F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRLVAGLVRGKRVDQAKAILHNS---------------------------------TKSASRNVMVTLKSAVAN---WSQ LNPDERLNDNELFVKAIFVDEGPSLKRLLPAPMGRAYRIRKRSNHLTIVVDKKLHVRKNDEVTVIAGN------DK-GKS GKVLKVFPQKG--RVI--VEGVNIRKRHMR----PT--QG-MPQ-GAIIEREFPIHVSNVK--------------KS--- --------------------------------------------MGQKVNPTGFRLG--II-KDWTSRWYD------D-G P-VIAEKIKQDQVIRNYV--HARLKKE---KAGIAKIVIERTT-K-HIKINIYAARPGAIVGHKGEEINNLSQELTRIVK IDVIEVIK---PEIEAQLIGENIAYQLENRVSFRRAMKMAIQQAMRA-GAEGVRIRCAGRLGGAEIARAEQYKEGKIPL- -HTLRANVDYASVTAHTIAGAIGIKVWVYMPVTDSIADFITRIRNAGSAKNKTTDI-PYTRVRENLSKLLLEKGYIKNYT VIT----S---E----QFPFIRVELKYM---QDG-------Q---HAIKEISRVSKPGRRVYQGK-DIKRYLGGLGLFIL STSKGILTDKEAREQNVGGEVLFRIYAVQQKIRIKLKSYDHSLVDKWALKIIDVVKQTEAIIFGPIPLPTKTHVYTVNRS PHVDKKSR-EQFAFSSHKRLIEIINPTARTIDMLMKLELPSGVDVEIKSKKSWLGKVVSDSMDKGIVVAVERRVQHPVYK KYFKKTTRLMAHDEN--NEAGVGDLVRITECRPLSKNKSCRLVEIVEKA------------------------------- -MPRSL-KKGPFIEF-KLEKRILDMNS---KGEKK----VVKTWSRSSMISPDFVGHTVAVHNGKTHVPVYVTE-NMVGH KLGEFAPTRLFRGHAGGKAEKG-GSAP----RKK-------- >BARIO_Chloroherpeton_thalassium_ATCC_35110 Concatenation of 2 sequences MPVRILKPRTPGTRFFSYPSFEE-ITTD------------KP-EKSLLVPNKSTGGRNNNGRVTSRH-MGGGHKRY---- YRIIDFK-R--NK-DGIPAKVATIEYDPNRTARIALLSYA-DGEKRYILAPNGIKVGDLIECGP-E-AD-IKVGNALPLK NIPVGIEVHNIEMRPGKGGQMARSAGSYAVLVAK--EGDYATLKMPSGELRKVRVECKATVGVIGNLEHENLSLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPKSP---WGQKSKGLKTR-KRKKASS-K-LIVRRR --------------------------------MSA-----ILGKKIGMTSLFD-ENRK---------AIPCTVIEAGPCF VSQVK----TVD----K--DGY--AAYQICF-------DK--KTAK----------PQLGHFK----------------- ---SG-VEPSYKMSEFRK-------EIFADEL-----NA---GD-EVKV--S-I-FKEGDTVKVSGVSKGKGFAGVVKRY HFGG-GSKTHGQSDRLRA-PGSVGGS-SFPS-RTFKGQRMAGRKGSDSVTIRGLKVVKVLPESN---------------- ----------LLVIKGA-VPGPNNSYLEIV--MEVKVLN-KDGAETGETVELKPVIF----EI-EP-NDHAIYLDVRSIM ANQHQGTHKVKTRSE--------VS-GGGRKPY---------RQKGTGNAR--------RGS---SR-SP----VM---- IGGGAIFGPK-P-HDYVVGINKKMKRLARISALSYKAKNN----------------E-IIVMEDY----VPS-E------ --IKTKLLL--MPSKN--D---VMYKSGRNISKLS-I---------------LEANKASTYDLLNNKT----LLIQKSAL ETLESRISEKYQKEV----LPKLRQQFKYSNVMMVPSLKKISINIGVG-AAAQDPKLLDNAVKELIAITGQKPEIRKAKK AISNFKLRAGQPIGCRVTLRKNRMYEFFDRLVALAIPRIRDFRGVSD-SSFDGRGNYTLGIREQIIFPEID-----IDKV PKITGMDITFVTS-----------------------AKTDEEAYALLKELGMPFMSRIG-K--LPVSITKGVKVE-L--- -K-D--D-KVIVSGPKGTLEQKL--RP-E--VTVSVDG-NN--VVV---TR-K--DDTRPSK-EMHGLYRVLINNMVTGV STGFTKKLELVGVGY--KAEIKK-DM--LVLS--LGFSHQIYFKT-P-A-EIKVEVP--A-PTNISISG-SDKELVGQVA AKIRSFR------PPEPY---QGKGVKYENEVIRRKEGK----------MIQKETDLMVADNSGAKRVRCIHVLG-TGRR Y--ATIGDMIVVSVKSAIPG-G-------AVKKKDVSKAVVVRTKKEYRRKDGSYIRFDENAVVLLN-TQGE-PRGTRIF GPVARELR-DKQYMKIISLAPEVIMN-L--STLQPAKGA-IKSGRRIG-RGQGSGS-GTTAGRGNKGHKARSGYT----- -SKNF-E-GGQMPLHRRLPK-FG--FSVVNVADLITLESFKSI-GIIGLK---------VLG--TGE-V-S-S-A-LTV- TAHYFSESAKEKIEKAGGKT-K---VQR--GRM---KGNA-ARGTEINFG----------SFALKAL--EPAWITSRQIE AARVAMNRHM------KRDGKIWIRIFPDKPVTKKPAETRMGSGK---------GSPEFWVAVVKP-GRIMFEV--DG-- VSKEVAMEGLRLASKKMPIKTKF-VKFVRRQRIKRRVRSVV---SGTEQRPRLTVFRSLSHIYAQLIDD---V--NGHTL VAASSM--PSK-GASL----LKG-KKSDVSREVGKALAEK--AKAKG-IDAVVFDRNGYRYH--GRVKALAEGAREGGLK F--------------------------------------------------------------ME-ARAILRHTPTSPRK MRLVADLVRGKQVDAAKAMLAHS---------------------------------TKHAARTVLQTLSSAVAN---YSQ ANPEKRLDESELIVKRIYVDQGVTLKRILPAPMGRAYRVRKRANHLTIIVDEKMHVKKNDMVKVISGN------DK-GVS GKILRVFPEKN--RVI--VEGVNMRKRHMR----PT--QE-YPQ-GAILEREMPIHASNVK------------------- ------------------------KVS-----------------MGQKVNPVGFRLG--VI-KDWDSRWYD------NTD K--IAGKIKEDQVIRNYV--ITRLKRQ---KAGVAKVVIERTS-K-NVRLYIYAARPGAVVGRSGEEINTLAQELGKIIK IDVIEIKR---PELDAQLVADNIASQLEGRISFRRAMKQAIQQARRA-GAEGIRIRCAGRLGGAEIARAEQYKEGKIPL- -HTIRANIDYAASTGFTITGTIGIKVWIYMPVTDPIADYITRIRNAGVAKHKTTDI-PHSKLKERLTVLLEEKGYIKSHT VVQ----G---E----KFPVIRVHLKYD---MYG-------K---PVIKEIKRVSKPGRRSYEGK-DIRKYLGGLGLYIL STSKGLLTDKEARSLGVGGEVLFSILAVQQKIRIKLKSYDHSLVDKWAEKIIEAVKQTDAIISGPIPLPTESQVFTVNRS PHVDKKSR-EQFMVASHKRLIEIINPSSKTIDLLMKLELPSGVDVEIKSRKERVGKVVSNKMQKSIVVAVERYVQHRVYK KYYKQTTKIMAHDEK--NDAKLGDTVRIMESRPLSKRKAWRLVEIIERA------------------------------- -MARSL-KKGPFIQE-RLLSRVLEMNQ---KGEKK----VIKTWSRSSMISPDFVGHTIAVHNGKTHIPVYVSE-NMVGH KFGEFAPTRTYRGHA------G---GK----AEKGGSAPKRK >BARIO_Cytophaga_hutchinsonii_ATCC_33406 Concatenation of 2 sequences MSLKKFRPITPGTRFRVAASYDD-VTTS------------TP-EKSLVVSIKKSGGRNSQGKMTMRY-IGGGHKQQ---- YRIIDFK-R--DK-HAIPAVVKTIEYDPNRTARIALLSYA-DGEKRYIIAPTGLEVGNTILSGP-G-IA-PEVGNCLPLS DIPLGTVVHNIELKPGKGAAMARSAGTYAQLVAR--EGKYATLKLPSGEMRMVLVVCYASIGTVSNADHMNLTKGKAGAT -RWA-----GRR-P-RVRGVAMNPVDHPMGGGEGRS----SGGH-PRSR---KGLYAKGGKTR-SANKYSK-N-MIVKKR --------------------------------MS----G-IIGKKVGMTSVYD-AVGN---------YVPCTVIEAGPCV ITQIK----TVE----T--DGY--KAVQLAF-------DD--KTTK----------PLLGHFK----------------- ---AG-VSPKRKLVEFKG---------FENEL-----TL---GQ-SLAA--QDV-FVEGDFVDVVGTAKGRGFQGVVKRH GFGGVGGQTHGQHNRARH-AGSIGAC-SFPA-RVFKGTRMAGRMGNNRVKIQNLQILKVYPEHN---------------- ----------LLVVSGS-VPGSKNSYVLIE--MELSLLN-IKGKDTGKKVVLSDDIF----AV-EP-NNHAIYLDVKQYL AHQRQGTHKAKERAE--------VS-FSTKKLK---------KQKGTGGAR--------AGS---RK-SP----IF---- VGGGTIFGPR-P-RTYGFKVNKKVKDLARKSAFSHKLKES----------------N-VTVLENF----TLN-A------ --PKTKLFV--IADID--K---NIILSSRNLKKAK-V---------------VSVDQINTYDLVNADK----VVISEGSV SKIEPRLKDKYLNDI----LPELKKKFQYSSVMQVPKITKIVINKGIG-AAVADKKLVDVGVDELTLISGQKAVATKSKL DVSNFKLRANMPIGAKVTLRGNHMYEFLDRLTAVALPRVRDFKGIND-KGFDGRGNYTLGVKEQIIFPEIS-----IDKI NKITGMDITIVTT-----------------------ANTDEESFELLKAFGMPFMSRIG-K--LPVTLPEKVELS-V--- -S-P-SN-LVTVKGPKGTLTQQV-D-V-D--IKVSVED-GK--VVV----A-R--PTEKRHK-ALHGLYRSLISNMVQGV SQGYKVELELVGVGY--KATATN-NI--LELS--LGYSHGIFLKL-P-S-EISASAEKGK-NPIVTLEC-IDKQLIGQVS AKIRSLR------KIEPY---KGKGVRFKGEVVRRKAGK----------MIQQESRLSVADNSGAKEVLVIRVLG-TGKR Y--ASIGDKVVVTVKSAISS-S-------NMKKGTVSKAVVVRTKKEVKRADGSYIRFSDNAAVLLN-NNDE-PRGTRIF GPVARELR-DKQFMKIVSLAPEVLMK-L--HTLRPAKGS-VKTSKRIG-RGTGSGR-GGTSTKGHKGAKSRSGYS-S--- -KIGF-E-GGQMPLQRRLPK-FG--FKPINLDELIDTALMNQN-GLIGVK---------VLA--RGE-VKS-I-K-AEI- IAHAFSASASEAITNAGGKV-K---QQK--GRV---TGVA-TRGHRIAFG----------SFAIKSL--EGGWITARQIE AARIAMTRAM------KREGQVWIRVFPDKPITQKPAEVRMGKGK---------GAPEYWVACIKP-GTILFES--GG-- VSIETAQESLRLAAQKLPFKTKF-IKDLRRLRIKRGIRNKI---SGTAEKPRLSVFRSNTGISAQLIDD---I--SGLTL ASCSSV-EFKS---------SKG-TKCEISTLVGKKIAEK--AATKG-IKNIVFDRGGFLYH--GRVKALAEGAREGGLA F-------------------------------------------------------------AKGAVKAHLNNVPTSTRK MRLVADLVRGQRVTLALGILKYQ---------------------------------AKQGARKLEKLVLGSVAD--WQA- KNSEARVEDADLYIREIFVDGGRVLKRLRTAPQGRAYRVRKRSNHITIVIDSKLHVRTGDNVIVISGD------DK-RKS GKVLSVDKENQ--KAI--VEGINIVTKHNK----PT--AN-VPN-GGIVKKEAPIHISKLM-IADPKT-------GK--A --TRIGRKE---DK--------NGMVR---YAKQSG---EVI--MGQKVNPIGFRLG--VV-KGWESNWYG------G-K T--FADKLVEDEQIRKYV--LARIP-----KGGISKIVIERTI-K-RVTLTINTARPGVVIGKGGAEVDKIKEELKKIVQ INIFEIKR---PEMEALLVGESIAQQLKARISYRRAMKQAIAGTMRV-GALGIKIKLSGRLGGAEMARTDQYKEGRIPL- -HTLRADIDYAVSEALTVYGKIGIKVWIF---MDPIADYLTKIRNAIKAKHRVVEV-PASNIKKEITKVLFDKGYIQSYK FEE----S---A----VQGSIKIALKYH--PLTK-------E---SAIVKIERISKPGLRKYTHAETMPRVLNGLGVAIV STSKGIMSDKEAKNLNIGGEVLCFVY-MNQKIRIKLKSYDHNLVDKSSERIVRAVKATGAVVSGPIPLPTEKEIFTVLRS PHVNKKSR-DQYQLCTYKRLVDIYSTSSKTVDALMKLELPSGVDVEIKVRKERTGKVVSNKMNKSITVAVERKVKHAKYG KFIHKTTKLMAHDEN--QECGIGDTVRVMETRPLSKLKRWRLVEVIEKA------------------------------- -MSRSL-KKGPYIDF-RLDNKVQALND---SAKKT----VIKTWSRRSMISPEFVGHTFAVHNGNKFIPVYVTE-NMVGH KFGEFSPTRTFKGHA----------AK----GKK-------- >BARIO_Flavobacterium_johnsoniae_UW101 Concatenation of 2 sequences MSVRKLKPITPGQRFRVVNGYDA-ITTD------------KP-ERSLIAPIKNSGGRNSQGKMTMRY-TGGGHKQR---- YRIIDFK-R--TK-DGIPATVKSIEYDPNRTAFIALLAYA-DGEKTYIIAQNGLKVGQKLVSGP-E-SQ-PEIGNTLPLS RIPLGTVISCIELRPGQGAVIARSAGTFAQLMAR--DGKYATIKMPSGETRLILLTCSATIGAVSNSDHQLVVSGKAGRT -RWL-----GRR-P-RTRPVAMNPVDHPMGGGEGRS----SGGH-PRSR---NGLPAKGYRTR-SKKNPSN-K-YIVERR --------------------------------MS----G-LIGKKIGMTSIFD-ENGK---------NIPCTVIEAGPCV VTQVR----TNE----V--DGY--EALQLGF-------DD--KSTK----------AALGHFK----------------- ---AG-TVAKKKVVEFQD---------FATEQ-----KL---GD-LIDV--S-I-FEEGEFVDVQGVSKGKGFQGVVKRH GFGGVGQATHGQHNRLRA-PGSVGAS-SYPS-RVFKGMRMAGRMGGDNVKVQNLRVLKVVAEKN---------------- ----------LLVVKGC-IPGHKNSYVIIQ--MEVKVLD-FNGKDTGRKVQLSDSVF----AI-EP-NNHAVYLDVKQYL ANQRQGTHKAKERAE--------VT-GSTRKIK---------KQKGTGTAR--------AGS---VK-NP----LF---- KGGGTVFGPR-P-RSYSFKLNKNLKRLARKSAFSIKAKES----------------N-IIVLEDF----NFE-A------ --PNTKLFV--LGESN--K---NVYLSSRNLKASN-V---------------VTSSELSTYAILNTNN----LVLLEGSL ELIEPRLKEEYKSRV----ISALKEEFGYTNVMQVPKLEKIVLSRGVG-AAVSDKKLIDYAVDELTKITGQKAVSTISKK DVASFKLRKGMPIGAKVTLRGERMYEFLDRLITSALPRVRDFGGIKA-TGFDGRGNYNLGVLEQIIFPEID-----IDKV NKISGMDITFVTT-----------------------AKTDKEAKSLLAELGLPFMSRIG-K--SPIVIPAGVTVE-V--- -K-D--G-IITVKGKKGQLVQEF--SD----VNVTVEG-DQ--VLV----E-R-SSDHKDHR-AKHGLFRSLISNMVVGV SEGFTKELELVGVGY--RASNQG-QK--LDLA--LGYSHNIVLEIAP-EVSLETISEKGKNP-IVKLTS-FDKQLLGQVA AKIRGFR------KPEPY---KGKGVKFVGEVLRRKAGK----------MVQQESRLKVADNTGAKEVLTIRVLG-TKRR Y--ASVGDKIVVSIKDATPN-G-------NVKKGAVSTAVVVRTKKEVRRADGSYIRFDDNACVLLN-AAGE-MRGTRVF GPVARELR-EKQFMKIVSLAPEVLMN-L--SNLQPAEGSTHNQNKRVG-RGEGSGK-GGTAARGHKGAKSRSGYS-K--- -KIGF-E-GGQMPLQRRVPK-FG--FKNVNLDTLVSMTDFVAN-RLASVK---------ILG--RGE-L-K-A-K-LKV- TAHKFTATAKAAIEAAGGEA-K---VQK--GRM---KGNS-QRGHELSNG----------MFGIKSVHEDGMFLTSRQIE AARIAATRYM------KREGQLWIKIFPDKPITKKPLEVRMGKGK---------GAVEYWAAVVKP-GRIMFEV--GG-- VPLSVAKEALRLAAQKLPVKTKFVVKSERRQRIKFRIRKTI---SGSAAKPRLSVFRSNKEIYAQLIDD---V--NGVTI LAASSR-EKEI---------AKG-TNVEIAAAVGKLVAEK--ALKAG-IDTITFDRGGYLYH--GRIKSLAEGARAAGLK F-------------------------------------------------------------KSI-AFAKLNNCPTSPRK MRLVADLVRGQKVERALNILRFS---------------------------------SKEASRKLEKLLLSAINN---WEQ KNSEGNLEEAGLFVKEIRVDGGMMLKRLRPAPQGRAHRIRKRSNHVTIVLGAKLKIKSGDIVRVIAGD------HK-GAE GKVLRVYREKN--KAI--VEGVNLVSKHTK----PS--AK-NPQ-GGIVKKEASIQISNIA-LIDPKT-------KE--T --TRVGIRV----E--------GDKVR---FSKKSN---QVL--MGQKTNPIGNRLG--II-RGWDSNWYG------G-N D--YGDKLAEDHKIRKYI--HARLS-----KASVSKVIIERTL-K-LVTVTITTARPGIIIGKGGQEVDKLKEELKKVVQ INIFEIKR---PELDAYLVATSIARQIESRISYRRAIKMAIAASMRM-NAEGIKVLISGRLNGAEMARSEGFKEGRIPL- -STFRADIDYALAEAHTTYGRMGIKVWIM-MYTDPIADYLTRVRNAVAANHKVVEI-PASNLKKEITKILFDQGYILSYK FEQ----N---T----VQGSIKIALKYD--KDTK-------E---PVIKDIQRISKPGLRKYAGAAKLPRILNGLGIAIV STSKGLMTGKQAKQLNVGGEVICYVY-MSQKIRIKLKSYDHMLVDKSAEKIVKTVKTTGAVVTGPIPLPTHKKLFTVLRS PHVNKKAR-EQFEVMSYKRLIDIYSSSSKTIDALMKLELPSGVEVEIKVRKERIGVVTSNKMDKSIVISEVRKVKHPLYG KFVLKTKKYVAHDET--NDCNIGDTVRISETRPLSKTKCWRLVEILERA------------------------------- -MARSL-KKGPFVHY-KLDKKVQENVE---SGKNS----VVKTWSRASMITPDFVGQTIAVHNGRQFVPVYVTE-NMVGH KLGEFSPTRSFRGHA------G-AKNK----GKK-------- >BARIO_Flavobacterium_psychrophilum_JIP02/86 Concatenation of 2 sequences MSVRKLKPITPGQRFRVVNGFDA-ITTD------------KP-ERSLIAPIKNSGGRNSQGKMTMRY-TGGGHKQR---- YRIIDFK-R--TK-DGIPASVKSIEYDPNRTAFIALLAYA-DGEKTYIIAQNGLQVGQKVVSGE-G-SA-PEIGNTLPLS KIPLGTVISCIELRPGQGAVIARSAGTFAQLMAR--DGKYATIKMPSGETRLILLTCSATIGAVSNSDHQLIVSGKAGRT -RWL-----GRR-P-RTRPVAMNPVDHPMGGGEGRS----SGGH-PRSR---NGIPAKGYRTR-SKKNPSN-K-YIVERR ---------------------------------MS---G-LIGRKIGMTSIFD-ENGK---------NIPCTVIEAGPCV VTQVR----TIG----V--DGY--EALQLGF-------DD--KSTK----------ADLGHFK----------------- ---AG-TVAKKKVVEFQD---------FVSEH-----KL---GD-VISV--D-L-FSEGEFVDIQGVSKGKGFQGVVKRH GFGGVGQATHGQHNRLRA-PGSVGAS-SYPS-RVFKGMRMAGRMGGDNVKVQNLRVLKVVAEKN---------------- ----------LLVIKGC-IPGCNNSYVIIQ--MEVKVLN-INGKETGRKVQLSDSVF----AI-EP-NKHAVYLDVKQYL ANQRQGTHKAKERAE--------VA-GSTRKIK---------KQKGTGTAR--------AGS---AK-NP----LF---- KGGGRVFGPR-P-RSYSFKLNKTVKRLARRSAFSIKAQEA----------------N-IIVVEDF----VFE-A------ --PNTKLFV--LGDSN--K---NVYLSSRNLKATN-V---------------LTNSELSTYAILNANN----LVLLEGSL EGIEPRLKEEYKSRV----ISALTEEFGYKNVMQVPKLEKIVISKGVG-AAVSDKKLIDYAVEELTKITGQKAVATISKK DVASFKLRKGMPIGAKVTLRGERMYEFLDRLVTSSLPRVRDFSGIKA-TGFDGRGNYNLGVLEQIIFPEID-----IDKV NKISGMDITFVTS-----------------------ATTDKEAKSLLTELGLPFMSRIG-K--NPIAIPAGVTVE-V--- -N-N--S-IVTVKGKLGQLTQNY-TNN----VTVKVEE-GQ--VIV---ER-A--ADSKQER-AQHGLYRALINNMVAGV STGFTKELELVGVGY--RASNQG-QK--LDLA--LGFSHNIVLEI-A-S-EVTLETN----P-IVKLTS-FDKQLLGQVA AKIRGFR------KPEPY---KGKGVKFVGEVLRRKAGK----------MVQQESRLRVADNTGAKEVLTIRVLG-TKRR Y--ASVGDKIVVSIKDTAPN-G-------SVKKGSVSTAVVVRTKKEVRRADGSYIRFDDNACVLLN-AAGE-MRGTRVF GPVARELR-EKQFMKIVSLAPEVLMN-L--SNLQPAEGSTHNQNKRLG-RGEGSGK-GGTSARGHKGAKSRSGYS-K--- -KIGF-E-GGQMPLQRRVPK-FG--FTNVNLDNLVDMAVFITS-RLATVK---------ILG--RGE-L-K-A-K-LKV- SAHKFTATAKAAIEAAGGEA-K---VQK--GKM---KGNS-QRGHELSNG----------MFGIKSVHEDGMFLTSRQIE AARIAATRFM------KREGQLWIKIFPDKPITKKPLEVRMGKGK---------GAVEYWAAVVKP-GRIMFEV--GG-- VPLSVAKEALRLAAQKLPCKTKFVVKSDRRQRIQYRIRKIV---SGTAARPRLSVFRSNKEIYAQLIDD---V--NGVTL ATASSR-EKGV---------NTG-TKIEVAIAVGKLIGET--ALKAG-IDTVTFDRGGYLYH--GRVKSLAEGARAAGLK F-------------------------------------------------------------NKSIAFAKLNNCPTSPRK MRLVADLVRGQKVDRALNILRFS---------------------------------SKEASRKLEKLVLSVIAN--WQA- KNPEANMEEAGLFIKTITVDGGMMLKRLRPAPQGRAHRIRKRSNHVTIVLGSKLKIKTGDIVRVIAGD------HK-GAE GKVVKVDREKN--KAI--VEGVNMVSKHTK----PS--AK-SPQ-GGIVKKEAPIQISNVS-LIDPKT-------KE--A --TRVGIRV---EG--------DKKVR---FSKKSN---QVL--MGQKTNPIGNRLG--II-RGWDSNWYG------G-N D--YGDKIAEDYKIRKYI--HARLS-----KASVSKVIIERTL-K-LVTVTITTARPGIIIGKGGQEVDKLKEELKKVVQ INIFEIKR---PELDAFLVATSICRQIESRISYRRAIKMAIAASMRM-NAEGIKVLISGRLNGAEMARSEGFKEGRVPL- -STFRADIDYALAEAHTTYGRMGIKVWIM-MYTDPIADYLTRVRNAAKANHKVVEI-PASNMKKEITKILFDQGYILSYK FED----N---A----VQGSIKIALKYD--KVTK-------E---SVIRDIQRISKPGLRKYSGSSTIPRILNGLGIAIV STSKGLMTGKLAKQLNVGGEVICYVY-MSQKIRIKLKSYDHMLVDKSAEKIVKTVKSTGAVVTGPIPLPTHKKLFTVLRS PHVNKKAR-EQFEVMSYKRLIDIYSSSSKTIDALMKLELPSGVEVEIKVRKERIGVVTSDKMDKSIVVAQVTRVKHPLYG KFVLKTKKFVAHDET--NDCNVGDTVKIMETRPLSKSKCWRLVEIIERA------------------------------- -MARSL-KKGPFVHY-KLDKKVQENIA---GGNKG----VVKTWSRASMITPDFVGQTIAVHNGRQFVPVYVTE-NMVGH KLGEFSPTRSFRGHA------G-AKNK----GKK-------- >BARIO_Gramella_forsetii_KT0803 Concatenation of 2 sequences MSVRKLKPITPGQRFRVVNGYDA-ITTD------------KP-EKSLLAPIKKSGGRNSQGKMTMRY-KGGGHKKR---- YRVIDFK-R--DK-QGIPATVASIEYDPNRTAFIALLNYQ-DGEKRYIIAQNGLQVDQNVVSSN-E-AATPEIGNAMPLA NIPLGTVISCIELRPGQGAVMARSAGAFAQLLAR--EGKYATIKLPSGEIRRVLALCMATIGAVSNSDHQLMIGGKAGRS -RWL-----GIR-P-RTRPVAMNPVDHPMGGGEGRA----SGGH-PRSR---KGLPAKGFKTR-SRTKASN-K-YIVERR --------------------------------MS----G-LIGKKIGMTSIFD-ENGK---------NIPCTVIQAGPCV VTQVR----TKE----V--DGY--EALQLGF-------DD---VGK----------AAEGHAK----------------- ---AG-TVAKRKVVEFQG---------YNEDY-----KL---GD-SVTV--E-H-FKEGEFVDIAGTSKGKGFQGVVKRH GFGGVGQATHGQHNRLRA-PGSIGAA-SYPA-RVFKGMKMAGRMGGERVKIENLRVLKVVADKN---------------- ----------LLVIKGC-VPGSKNSYVIIS--MEIAVLD-IKGKETGRKAKLSDSVF----AI-EP-NDHAVYLDVKQYL ANQRQGTHKAKERAE--------IK-GSTRKIK---------KQKGTGTAR--------AGS---IK-SP----IF---- KGGGRVFGPR-P-RNYGFKLNKNLKRLARKSALSIKANDK----------------A-IMVIEDF----SFD-T------ --PKTKLIV--LGDSN--K---NVYLSSRNLKTSE-V---------------ISSSELSTYKILNAKS----IVFLEGSL EGIEPRLRQEYNERV----KSALKEEFSYSNIMEVPKLTKIVISRGVG-GAVADKKLIDHAIDELSAISGQKAVSTISKK DVASFKLRKGMPIGAKVTLRGYRMYEFLDRLITSALPRVRDFNGIKS-NGFDGRGNYNLGVTEQIIFPEID-----IDAV NRIAGMDITFVTT-----------------------ADTDKEAKALLTELGLPFMSRIG-K--SPVTIPEGVTVDHK--- -D-G----VVTVKGKLGELKQEI--RD----IDVKIED-NV--ITF---ER-S--SEKSDQK-AKHGLYRALVNNMIEGV TNGYTKSLELVGVGY--RATNQG-NK--LDLA--VGYSHNIVLDLAP---EVKVETN----P-IVKVTS-HDKQLVGQVA AKIRSFR------APEPY---KGKGIKFVGEQLRRKAGK----------MVQQESRLKVADNTGAKEVLAIRVLG-TKKR Y--ASVGDKIVVSVKEATPN-G-------SIKKGAVSTAVVVRTRKEVRRPDGSYIRFDDNACVLLG-PQGE-MRGTRVF GPVARELR-DKQFMKIVSLAPEVLMD-L--SNLKPAEGSVRKNSKRIG-RGEGSGK-GGTATRGHKGAKSRSGYS-K--- -KIGF-E-GGQMPLQRRVPK-FG--FTNINLDTLVDMDVLVEN-GLAGVK---------ILG--RGE-L-K-A-K-LKI- SVHKFTASAKEAIEAAGGEV-K---QQK--GRM---KGLS-QRGHRLSNG----------TFGIKSM--DSSFVTARQIE AARIAATRYM------KREGSIWIKIFPDKPITKKPLEVRMGKGK---------GAVEYWAAVVKP-GRIMFEI--GG-- VPMDVAKEALRLAAQKLPVRTKFVVKLDRRNKIRKRIRKDI---VGTTSRPRLSVFRSNKEIYAQIIDD---V--EGKTL ASASSR-DKDI-------ASASA-DRKEQAQMVGKTIAEK--AKKAG-IDTISFDRGGYLYH--GRVKSLAEGAREGGLK F-------------------------------------------------------------KKQVAFAKLNNCPTSPRK MRLMADLVRGEKVEKALHILKFS---------------------------------KKEASNRLEKLLVSAIAN--WQA- KNEDANLEEAELFVKEIRVDGGSMLKRLRPAPQGRAHRIRKRSNHVTLVLGAKLKIKSGDTVRVIAGD------HK-GQE GKVQKVLIEKN--KAI--VEGVNMISKHEK----PS--AS-NPQ-GGIKEKEAPIHISNLS-LID-KN-------GD--T --TRVGYKE----E--------DGKVR---FSKKSN---EVI--MGQKTNPIGNRLG--II-RGWESNWYG------G-N D--YGDKLAEDDKIRKYI--HARLS-----KASVSRVIIERTL-K-LVTVTITTARPGIIIGKGGQEVDKLKEELKKIVQ INIFEIKR---PELDAHLVGASVARQIENRISYRRAIKMAIAAAMRM-NAEGIKIEISGRLNGAEMARSESYKDGRIPL- -STFRADIDYALVEAHTTYGRLGVKVWIM-MNTDPIADYLTRIRNANAANHRVVEI-PASNVKKEITKILFDQGYILSYK FED----T---T----AQGTIKIALKYD--KLTK-------E---PVIKKIQRISKPGLRKYAGSTEIPRILNGLGIAVV STSHGVMTGKQAKANKVGGEVLCYVY-MSQKIRIKLKSYDHNLVDKSAEKIVKTVKTTGAVVTGPIPLPTNKKIFTVLRS PHVNKKSR-EQFELSSYKRLLDIYSSSSKTIDALMKLELPSGVEVEIKVRKERVGVVTSNKMQKSIVVSEVKKVKHPMYG KFVLKTKKYVAHDEN--NDCNEGDTVKIMETRPLSKSKTWRLVEIIERA------------------------------- -MARSL-KKGPFVHY-KLEQKVAQNVE---SGKKA----VIKTWSRASMITPDFVGQTIAVHNGKQFVPVYVTE-NMVGH KLGEFSPTRSFRGHA------G-AKNK----GRK-------- >BARIO_Parabacteroides_distasonis_ATCC_8503 Concatenation of 2 sequences MGIRKLKPTTPGQRHKVIGAFDK-ITAS------------TP-EKSLVVGKKSTGGRNNTGKMTMRY-IGGGHKQK---- YRIIDFK-R--NK-DGIPATVKSIEYDPNRSSRIALLYYA-DGAKSYIIAPNGLEVGQTVVSGS-D-AA-PEVGNTLPMA NIPVGTIIHNIELRPGQGAKMVRSAGAFAQLTSK--EGAYAIIKMPSGETRKILAACKATIGAVGNSDHALEKSGKAGRS -RWL-----GRR-P-RNRGVVMNPVDHPMGGGEGRS----SGGH-PRSR---NGLYAKGLKTR-APKKHSS-K-YIIERR ---------------------------------MP---G-LLGKKIGMTSVFS-AEGK---------NLPCTVIEVGPCV VTQIK----TLE----K--DGY--EAVQLGF-------QE--KTTQ----------PEMGHFK----------------- ---AG-VAPQRHLAEFKN---------FETEY-----KL---GD-VITV--D-F-LEDAGFVDVVGTSKGKGFQGVVKRH GFGGVGQTTHGQHNRARK-PGSIGAC-SYPA-KVFKGMRMGGQMGNERVTVQNLQVIKVMPEHN---------------- ----------LLLVKGS-VPGAKGSILLIE--MELSVFN-IKGEDTGRKVTLNDAIF----GI-EP-NDHAIYLDVKQYL ANQRQGTHKSKERSE--------VS-GSTRKLI---------RQKGGGGAR--------RGD---IN-SP----VL---- VGGGRVFGPK-P-RDYEFKLNKKVKSLARKSALSYKAKNN----------------A-IVVVEDF----TME-A------ --PKTKLMV--LPEKN--N---LVYLSARNLEKAS-V---------------ITASELNTYAVLNAVN----LVLTESSV AVVEASLKKEYQDRI----VPALTKEFGYKSVMQVPVLKKIVINQGLG-MATADKKIIDIAISELSTITGQKAVATVSKK DISNFKLRKKMPIGVMVTLRREQMYEFLERLVRVALPRIRDFKGIES-K-LDGRGNYTLGIQEQIIFPEIN-----IDNI TKILGMNITFVTS-----------------------AKTDEEGYALLREFGLPFMSRIG-K--LPIHVPAGVTVT-I--- -K-D--N-VVTVKGPKGELVQEV--NP-D--INVTLED-GV--IHL---TR-P--TDDKNHR-ALHGLYRSLINNMVVGC SEGYKKELELVGVGY--RVSNTG-QL--LDLS--LGYTHNIYLQL-P-K-EVKVETK--S-EPLIILES-ADKQLLGQIC AKIRSFR------MPEPY---KGKGIKFVGEEIRRKSGK----------MIQQESRLVVADNSGAKEALCIRVLG-TRKR Y--ATVGDVIVVAIKSVIPA-S-------DVKKGAVSKAIIVRTKKEIRRPDGSYIRFDDNACVLLN-AGGD-IRGSRIF GPVARELR-ATN-MKIVSLAPEVLMN-L--SNLKPAEGS-TKTRKRIG-RGPGSGL-GGTSTRGHKGAKSRSGYK-N--- -KIGF-E-GGQMPIQRRLPK-FG--FKNINIDTLIGINELMEA-GFISVK---------ILG--NGS-L-T-A-K-LEV- EAHAFSKSAEAAIQAAGGTV-R---QQK--GRM---KGEA-QRGNQLAFG----------SFGIKSL--ENKWITGRQIE AARIAVTRYM------QRQGQVWVRIFPDKPITKKPAEVRMGKGK---------GNPEGFVAPVTP-GRLIFEI--EG-- VPFDIAKEALRLAAQKLPVTTKF-VKLERRLKIKAGVRGKI---SGTTERPRLTVFRSNKQIYAQVIDD---T--TGKTL AAASSL-KLDV----------KA-PKKEIAAKVGELIAKG--AQEAG-VQTVVFDRNGYLYH--GRIKELADAARNGGLK F-------------------------------------------------------------QKTMYFAKLNNVPTSPRK MRLVADMIRGMEVFRALGVLKFS---------------------------------NKEAAARVEKLLRSAIAN---WE- QKNERKAEAGELCVSSISVDCATTLKRMRPAPQGRGYRIRKRSNHVTLFVDTKLHIKKGDIVFVNAGE------DK-GKT GRVLQVLVKDN--RAI--VEGINVVSKHTK----PN--AK-NPQ-GGIEKKEAPIHLSNLN-VVDPKS-------GK--A --TRIGRKL---NE--------KGLVR---YSKKSG---EEI--MGQKVNPISNRLG--II-RGWDSNWYG------G-K N--YGDTLLEDSKIRKYL--NARLA-----KASVSRIVIERTL-K-LITITVCTSRPGIIIGKGGQEVDKLKEELKKIVQ INIFEVKR---PELDAVIVANNIARQLEGKIAYRRAVKMAIASTMRM-GAEGIKIQISGRLNGAEMARSEMYKEGRTPL- -HTLRADIDYALAEALTKVGLLGVKVWIC--MTDPIADYLTRLRNAIKAKHRVVEV-PASNLKKEITKILFDKGYILNFK FVE----D---G----PQGTIKIALKYD--LVNK-------V---NAIKKLERVSTPGLRKYTGYKEMPRVLNGLGIAVL STSKGVMTDKEARDLKIGGEVLCYVY-MSQKIRIKLKSYDYSLVDKSAEKIVKTVKATGAIVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSYKRLIDIYSSTAKTVDALMKLELPSGVEVEIKVRKERTGVVTSNKMDKSITVAIKWKEKHPIYG KFVNKTKKYHAHDEN--NECNIGDTVKIMETRPLSKTKRWRLVQIIERA------------------------------- -MSRSL-KKGPYINV-KLEKKVLAMNE---SGKKA----VVKTWARASMISPDFVGHTIAVHNGNKFIPVFVTE-NMVGH KLGEFSPTRTFRGHA------G----N----KKK-------- >BARIO_Pelodictyon_luteolum_DSM_273 Concatenation of 2 sequences -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------MG---A-ILGKKIGMTRLYN-DKRE---------AVPCTIIQAGPCF VTQVK----NAE----K--DGY--DAVQIGI-------GE--RVTK----------PMLGHYK----------------- ---AG-VTPGYMMAEFDA-------SMFDVEL-----AA---GS-PVSV--E-S-FKEGEIVNVLGVSKGKGFAGVVKRH NFGG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RTFKGTRMGGRMGSDNVTVRNLQVVKIMAESN---------------- ----------LIMVKGS-VPGPKNSYVKIV--MELKVLN-TAGAETGEVVTLRDDIF----GA-EV-SEHAIWLDVKSIL ANKRQGTHKSKTRAE--------VR-GGGRKPY---------RQKGTGNAR--------QGS---TR-SP----LM---- IGGGTIFGPT-P-HGYDQKVNRKVKQLARRSAFSAKAQEG----------------R-ILIVEDF----ALA-E------ --IKTKLML--TPDYN--M---VIARSGRNIEALN-I---------------MTAEKASTYDILNSHT----VLFQKTAL KKLEARFETLYREKV----TKALSERFGYKNVMNIPRLQKISINIGVG-EAASEPKLLETAIQELAQITGQKPQIRKSKK AISNFKLREGQAIGCRVTLRRKAMYEFFDRFVSLAVPRIRDFRGLSD-TSFDGRGNYTIGVREQIIFPEID-----IDKI PKICGMDISFVTS-----------------------AKTDEEAYVLLAELGMPFMSRIG-K--MPIAIGNEAKIE-V--- -K-G--G-IITVTGPKGVLDQPM-VEE----VRIVEED-GK--VLV----Q-R--INDKRAR-AMHGLYRMLVSNMIQGV TTGFTRKLEIAGVGF--RAEMKS-DL--LALT--LGYSHMIYFKA-P-E-GIKMETP--D-QVTVLISG-IDKALVGQVA AKIRSFR------KPEPY---RGKGIKYEGEIIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--ASLGDQVIVSVKAAVPG-G-------VVKKKEVCKAVVVRCVKEQRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DRRYMKIVSLAPEVLMD-L--SSLRPAKGA-VKNKKRVG-RGQGSGN-GTTAGKGNKGQQARSGYK----- -RPIN-E-GGQIPVYRRLPK-FG--FTPVNLSQILGVIELKVL-CHASFK---------VLG--NGE-I-T-A-A-VKI- TAHGFSKSAEAKITAAGGEA-K---TQR--GRM---KGNA-GRGTSVAFG----------SFGLKAI--EPAWITSRQIE AARVAMNRYM------KRDGKIWIRIFPDKPVSKKAAETRMGSGK---------GSPEFWVAVVKP-GRIMFEA--DG-- VPMEVATEAFRLAAKKLPIKTRF-IKASRRQKIKDRSRFSV---AGTQEKPRLCVYRSLSQIYAQLIDD---S--GKKTI MAVSSM-SKEN-KE-L-----KG-SKTEVCHRVGKQIAEK--ALANG-ITNVVFDRNGFRYH--GRIKALADGAREAGLI F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRLVAGLVRGKAVDQAKAILLNS---------------------------------TKAASRNALQTLKSAVAN---YAQ LNPDERVGDQELFVKSVFVDEGATLKRMLPAPMGRAYRVRKRSNHLTIIVDKKLHVKKNDMVVVLSGN------DR-GKS GKVLRVYPVKN--RVI--IEGVNIRKRHMR----PT--QS-NPQ-GSIIEREFPIHASNVK--------------KS--- --------------------------------------------MGQKVNPTGFRLG--II-KDWTSRWYD------DSP V--ISGKIKEDHVIRNYV--QTRLKRE---KAGIARIIIERTT-K-HIKINIYAARPGAVVGRKGEEINNLSQELGRIVK IDVVEVVK---PEIESQLIGESIAYQLENRVSFRRAMKMAIQQAMRA-GAEGVRIRCAGRLGGAEIARAEQYKEGKIPL- -HTIRANVDYASVTAHTIAGTIGIKVWVYMPVTDSIADYITRIRNAGRAKNKTTDI-PYSKLRENISQLLQDKGYIKNFT VIT----T---E----KFPFIRIELKYT---ASG-------E---PSIKEITRVSRPGRRTYEGK-DIKKYLGGLGLYIL SSSKGVITDKEAREQGVGGEILFRIYAVQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKSHVYTVNRS PHVDKKSR-EQFSFASHKRLIEIINPTSRTIDMLMKLELPSGVDVEIKSKKSWTGKVVSDSMDKAIIVAVERRVQHPVYK KYFKKTTRLMAHDEK--NEAGMGDLVKVVECRPLSKRKSCRLVEIVEKA------------------------------- -MPRSL-KKGPFIDI-KLEKRILDMNS---RSEKK----VLKTWSRSTMISPDFVGHTIAVHNGKTHVPVYVSD-NMVGH KLGEFAPTRTFRGHAGGKAEKG-GSAP----KRK-------- >BARIO_Pelodictyon_phaeoclathratiforme_BU-1 Concatenation of 2 sequences MSYPA---------------FDE-ITKS------------TP-EKSLLVPLKKSGGRNAAGRKTSRH-RGGGHKRH---- YRIIDFK-R--NK-DGIPATVAAIEYDPNRSSRIALLHYN-DGEKRYILAPKGLNVGDKVESGE-K-VE-IKTGNTMPLK NIPLGTDIHNIEMKAGKGGQIVRSAGGFAVLAAR--EGDYVTLKLPSGEIRKLRVECRATIGVVGNTDHENIVLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPMSP---WGQLAKGLKTR-NKKKASQ-K-LIVRGR --------------------------------MGA-----ILGKKIGMTRLFN-EKRE---------AVSCTIIQAGPCF VTQVK----RAD----K--EGY--DAYQIGI-------GE--RVSK----------PLQGHYK----------------- ---AG-VAPGFKLAEFDF-------KELNQEL-----EL---GS-AVSV--E-S-FTEGEKVNVLGVSKGKGFAGVMKRH NFSG-GQRTHGQSDRQRA-PGSVGGS-SDPS-RVFKGTRMAGRMGSDNITVRNLVIFKIMPESN---------------- ----------LIVIKGS-VPGPKNSYVKIVEAMELKVLN-TGGTETGEVVTLRDDIF----GA-EI-SEHAMYLDVKSIL ANRRQGTHKSKTRGE--------VR-GGGRKPL---------RQKGTGNAR--------QGS---SR-SP----LN---- IGGGTIFGPV-P-HAYDQKVNKKVKLLARRSALSSKAKAG----------------Q-IVVIEDF----VFE-N------ --IKTKLML--TPGYD--L---IIARSGKNIAALN-I---------------MTADKASTYDILHSHT----LLVQKTAL KKIEARLETFFKEKV----TPNLVERFQYKNAMLVPKLKKISINIGVG-AAAAEPKLLEIALQELAQITGQKPQIRKSKK AISNFKLREGQAIGCRVTLRRKAMYEFFDRFVSLAVPRIRDFRGLSD-TSFDGRGNYTVGVREQIIFPEID-----IDKV PRISGMDISFVTS-----------------------ASTDEEAYVLLSELGMPFMSRIG-K--MPIPLSNQAKIE-I--- -K-D--S-NIRVSGPKGTLEQRL--TD-Q--VTVSEEN-GL--VTV------LRIDDSKKAK-AQHGLYRMLISNMVDGV TKGFTRKLEIAGVGY--RAELKN-DL--LALT--LGYSHMIYFKA-P-D-EIKIEVP--D-QVTVLVSG-IDKALVGQVA AKIRSFR------KPEPY---RGKGIKYEGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--ASLGDQIIVSVKAAVPG-G-------IVKKKDVCRAVVVRCVKESRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DRKFMKIVSLAPEVLMD-L--SSLRPAKGA-VKNKKRVG-RGQGSGN-GTTAGKGNNGQQSRSGYK----- -RPII-E-GGQVPVYRRLPK-FG--FTPVNLTQIITILDLKSL-LHASFK---------ILG--NGE-L-T-S-A-ITI- TAHAFSKSAEEKIAAAGGTV-K---TQR--GRM---KGNS-GRGTDVSFG----------SFGLKAI--EPAWITSRQIE AARVAMTRFM------KRDGKIWIRIFPDKPVTKKPAETRMGSGK---------GSPEFWVAVVKP-GRIMFEA--DG-- VPKEVATEAFRLAAKKLPIKTRF-IKASRRQKIKDRSRGNV---QGTSAKPRLCVYRSLSQIYAQLIDD---V--NGKTI LAASTL-SKDN-SA------LKG-SKSELCRIIGNQLGQK--ALAQG-ITCVVFDRNGFRYH--GRVKALADGAREAGLI F--------------------------------------------------------------ME-AKAILRDTPTSPRK MRLVAGLVRGKPVDLAKAILLNS---------------------------------TKAASRNVMMTLKSAVAN---YAQ RNPDERVSDQELFVKTIFVDEGTTLKRTLPAPMGRAFRIRKRSNHLTIVIDKKLHVKKNDSVVVISGN------DK-GKE GKILKVFPIKS--RVI--VEGVNIRKRHMR----PT--QG-QTQ-GSIIEREFPIHSSNVK--------------KS--- --------------------------------------------MGQKVNPTGFRLG--II-RDWASRWYD------D-S P-VISEKIKQDHVIRTYV--LARLKKE---RAGIARIIIERTT-K-HVKINIYAARPGAVVGRKGEEINNLSQELSRIVK IDVVEVVK---PEIEAQLIGDNIAYQLENRVSFRRAMKQAIQQAMRS-GAEGVRIRCGGRLGGAEIARSEQYKEGKIPL- -HTIRANVDYASVTAHTIAGTIGIKVWVYMPVTDSIADYITRIRNAGRAKNKTTDI-PYSKLRENLSQLLVEKGYIKNFT VIT----T---E----KFPFLRIDLKYT---AHG-------D---PAIKEISRVSKPGRRVYDGK-DIKKYLGGLGLYIL SSSKGVITDKEARAQGVGGEILFRIYAVQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKSHVYTVNRS PHVDKKSR-EQFSFSSHKRLIEIINPTSRTIDMLMKLELPSGVDVEIKSKKSWLGKVVSDKMDKSCVVAVERSVQHPVYK KYFKKTTKLTAHDEK--NEAGIGDLVKVVECRPLSKRKSCRLVEIIEKA------------------------------- -MPRSL-KKGPFIDI-KLEKRILDMNS---KGEKK----VIKTWSRSSMISPDFVGHTVAVHNGKNHVPVYVGD-NMVGH KLGEFAPTRSFRGHAGGKAEKG-GSAP----RKK-------- >BARIO_Porphyromonas_gingivalis_ATCC_33277 Concatenation of 2 sequences MGIRKLKPTTPGQRHKVIGAFDK-ITAS------------TP-EKSLVVGKKKTGGRNNTGKMTMRY-IGGGHKQK---- YRFIDFK-R--TK-DGIPATVKTIEYDPNRSSRIALLYYA-DGAKAYIIAPDGLEVGHTVMSGS-E-AA-PEVGNALPLA NIPVGTIIHNIELRPGQGAKMVRSAGSFAQLTSR--EGTYVVIKMPSGEVRRILSTCKATIGSVGNSDHALEKSGKAGRS -RWL-----GRR-P-HNRGVVMNPVDHPMGGGEGRQ----SGGH-PRSR---KGLYAKGLKTR-APKKHSS-K-YIIERR --------------------------------MP----G-LLGKKIGMTSVFS-AEGK---------NLPCTVIEVGPCV VTQVK----TLE----K--DGY--SALQLGF------VDA---TTK----------PLAGHFK----------------- ---AN-VAPKRHLAEFKN---------FEGEH-----KL---GD-VLNV--E-F-FSDADFVDVVGTSKGKGFQGVVKRH GFGGVGQATHGQHNRLRA-PGAVGAC-SYPA-KVFKGTRMAGQMGNERVTVQNLEVIKVMPEHN---------------- ----------LLLVKGS-VPGAKGSILLIE--MELSVYN-IKGEDTGKKVVLDDSIF----AI-EP-NDHAIYLDVKQYM ANQRQGTHKAKERSE--------LS-GSTRKLI---------RQKGSGGAR--------RGD---IN-SP----LL---- SGGARVFGPR-P-RNYTFKLNKKLKALARRSALSYKAKNN----------------E-IIVVEDF----NFD-A------ --PKTKLYV--LPEVN--K---NVYLSARNLPNTN-L---------------ILANLINTYTVLASKN----LVLTERSV AVVNANLKKDYQERI----VPALMKQFGYTSVMQVPVLKKIVINQGLG-MATGDKKIIDVAVSELTAITGQKAVPTVSKK DISNFKLRKKMPIGVMVTLRREQMYEFLERLVRIALPRIRDFKGIES-K-LDGRGNYTLGINEQIIFPEIN-----IDAI TKILGMNITFVTS-----------------------AQSDEEGYALLKEFGLPFMSRIG-K--LPISIPAGVTVS-H--- -K-D--E-IVTVKGPKGELSQYV--DP-R--ITVVIEG-GM--IHL---ER-K--TDDRIER-SLHGLYRSLINNMVQGV SAGFKRELELVGVGY--RASNQG-QL--LELS--LGFTHSIFMQL-P-K-EVTVETK--S-EPLIILES-ADKQLLGQVC MKIRSFR------KPEPY---KGKGVKFVGEQIRRKSGK----------MIQQESRLVVADNSGAKEALCIRVLG-TRRR Y--ASVGDIIVVSVKSVIPS-S-------DIKKGAVSKAVIVRTKKEVRRPDGSYIRFDDNACVLLN-AAGD-IRGSRIF GPVARELR-GTN-MKIVSLAPEVLMN-L--SSLKPAEGA-VKSRKRIG-RGPGSGL-GGTSTRGHKGAKSRSGYS-K--- -KIGF-E-GGQMPIQRRLPK-FG--FKNINLSVLISVEDLIAA-GLVSVK---------ILA--NGT-V-T-T-A-LTV- EAHAFSKTAEEAIVRAGGSV-R---QQK--GRM---KGFA-QRGNQLSFG----------SFGIKSL--QSKWITGRQIE AARIAVTRYM------QRQGQVWVRIFPDKPITKKGEGVRMGKGK---------GAPEGFVAPITP-GRIIFEV--EG-- VPYEIAKEALRLAAQKLPVTTKF-VKEQRRQKIKARVRGKI---SGTQERPRLTVFRSNKQIYAQLIDD---I--AGRTL ASASSL-KLEM----------TG-SKKEIAAKVGDEIAKA--ATEAG-ISTVVFDRNGYLFH--GRIKELADAARKGGLK F-------------------------------------------------------------LKQMYFAKLRNVPTSPRK MRLVADMIRGMEVNRALGVLKFS---------------------------------NKEASARVEKLLRSAVAN---WE- EKNERKAEEGELFVSRICVDGASTLKRLRPAPQGRGYRIRKRSNHVTIYVDTKLHIKKGDTVMVISGE------DK-GHS GRVLEVLVKEQ--RAI--VEGLNMIKKHAK----PS--AK-NPQ-GGIISKEAPIHISNLN-VVDPKT-------GK--A --TRIGRRL---NE--------NGLVR---YAKKSG---EEI--MGQKINPVSNRLG--II-RGWDSNWYG------G-R K--YGETLLEDSRIRQYL--NARLA-----KASVSRIVIERAL-K-LVTITICTARPGMIIGKAGQEVDKLKEELKRIVQ INIYEIRK---PELDAAIVAENIARQLEGKIAYRRAVKMAIASAMRM-GAEGIKIQVSGRLNGAEMARSEMFKEGRTPL- -HTLRADIDYALAEALTKVGLLGIKVWIC--MTDPIADYLTRLRNAIMAGHRVVSV-PASNIKKEITKILFDKGYILNYK FEE----N---D----SQGIIKVALKYD--LAHK-------V---NAIKKLKRVSRPGLRKYVGYRDMPRVLNGLGIAIV STPRGVMTDKEARELKVGGEVLCYVY-MSQKIRIKLKSYDYMLVDKSAEKIVKTVKAAGAMVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSYKRLIDIYNSTAKTVDALMKLELPSGVEVEIKVRKERVGVVSSNKMDKTITVAVKWKEKHPIYG KFVNKTKKYHAHDEK--NECGIGDTVRIMETRPLSRTKRWRLTEIIERA------------------------------- -MSRSL-KKGPYINL-KLEKKVLAMNE---SGKKA----VIKTWARASMISPDFVGHTIAVHNGNKFIPVFVTE-NMVGH KLGEFSPTRTFRGHA------G----N----KKK-------- >BARIO_Porphyromonas_gingivalis_W83 Concatenation of 2 sequences MGIRKLKPTTPGQRHKVIGAFDK-ITAS------------TP-EKSLVVGKKKTGGRNNTGKMTMRY-IGGGHKQK---- YRFIDFK-R--TK-DGIPATVKTIEYDPNRSSRIALLYYA-DGAKAYIIAPDGLEVGHTVMSGS-E-AA-PEVGNALPLA NIPVGTIIHNIELRPGQGAKMVRSAGSFAQLTSR--EGTYVVIKMPSGEVRRILSTCKATIGSVGNSDHALEKSGKAGRS -RWL-----GRR-P-HNRGVVMNPVDHPMGGGEGRQ----SGGH-PRSR---KGLYAKGLKTR-APKKHSS-K-YIIERR --------------------------------MP----G-LLGKKIGMTSVFS-AEGK---------NLPCTVIEVGPCV VTQVK----TLE----K--DGY--SALQLGF-------VD--ATTK----------PLAGHFK----------------- ---AN-VAPKRHLAEFKN---------FEGEH-----KL---GD-VLNV--E-F-FSDADFVDVVGTSKGKGFQGVVKRH GFGGVGQATHGQHNRLRA-PGAVGAC-SYPA-KVFKGTRMAGQMGNERVTVQNLEVIKVMPEHN---------------- ----------LLLVKGS-VPGAKGSILLIE--MELSVYN-IKGEDTGKKVVLDDSIF----AI-EP-NDHAIYLDVKQYM ANQRQGTHKAKERSE--------LS-GSTRKLI---------RQKGSGGAR--------RGD---IN-SP----LL---- SGGARVFGPR-P-RNYSFKLNKKLKALARRSALSYKAKNN----------------E-IIVVEDF----NFD-A------ --PKTKLYV--LPEVN--K---NVYLSARNLPNTN-L---------------ILANLINTYTVLASKN----LVLTERSV AVVNANLKKDYQERI----VPALMKQFGYTSVMQVPVLKKIVINQGLG-MATGDKKIIDVAVSELTAITGQKAVPTVSKK DISNFKLRKKMPIGVMVTLRREQMYEFLERLVRIALPRIRDFKGIES-K-LDGRGNYTLGINEQIIFPEIN-----IDAI TKILGMNITFVTS-----------------------AQSDEEGYALLKEFGLPFMSRIG-K--LPISIPAGVTVS-H--- -K-D--E-IVTVKGPKGELSQYV--DP-R--ITVVIEG-GM--IHL---ER-K--TDDRIER-SLHGLYRSLINNMVQGV SAGFKRELELVGVGY--RASNQG-QL--LELS--LGFTHSIFMQL-P-K-EVTVETK--S-EPLIILES-ADKQLLGQVC MKIRSFR------KPEPY---KGKGVKFVGEQIRRKSGK----------MIQQESRLVVADNSGAKEALCIRVLG-TRRR Y--ASVGDIIVVSVKSVIPS-S-------DIKKGAVSKAVIVRTKKEVRRPDGSYIRFDDNACVLLN-AAGD-IRGSRIF GPVARELR-GTN-MKIVSLAPEVLMN-L--SSLKPAEGA-VKSRKRIG-RGPGSGL-GGTSTRGHKGAKSRSGYS-K--- -KIGF-E-GGQMPIQRRLPK-FG--FKNINLSVLISVEDLIAA-GLVSVK---------ILA--NGT-V-T-T-A-LTV- EAHAFSKTAEEAIVRAGGSV-R---QQK--GRM---KGFA-QRGNQLSFG----------SFGIKSL--QSKWITGRQIE AARIAVTRYM------QRQGQVWVRIFPDKPITKKGEGVRMGKGK---------GAPEGFVAPITP-GRIIFEV--EG-- VPYEIAKEALRLAAQKLPVTTKF-VKEQRRQKIKARVRGKI---SGTQEKPRLTVFRSNKQIYAQLIDD---I--AGRTL ASASSL-KLEM----------TG-SKKEIAAKVGDEIAKA--ATEAG-ISTVVFDRNGYLFH--GRIKELADAARKGGLK F---------------------------------------------------------------M-YFAKLRNVPTSPRK MRLVADMIRGMEVNRALGVLKFS---------------------------------NKEASARVEKLLRSAVAN---WE- EKNERKAEEGELFVSRICVDGASTLKRLRPAPQGRGYRIRKRSNHVTIYVDTKLHIKKGDTVMVISGE------DK-GHS GRVLEVLVKEQ--RAI--VEGLNMIKKHAK----PS--AK-NPQ-GGIISKEAPIHISNLN-VVDPKT-------GK--A --TRIGRRL---NE--------NGLVR---YAKKSG---EEI--MGQKINPVSNRLG--II-RGWDSNWYG------G-R K--YGETLLEDSRIRQYL--NARLA-----KASVSRIVIERAL-K-LVTITICTARPGMIIGKAGQEVDKLKEELKRIVQ INIYEIRK---PELDAAIVAENIARQLEGKIAYRRAVKMAIASAMRM-GAEGIKIQVSGRLNGAEMARSEMFKEGRTPL- -HTLRADIDYALAEALTKVGLLGIKVWIC--MTDPIADYLTRLRNAIMAGHRVVSV-PASNIKKEITKILFDKGYILNYK FEE----N---D----SQGIIKVALKYD--LAHK-------V---NAIKKLKRVSRPGLRKYVGYRDMPRVLNGLGIAIV STPRGVMTDKEARELKVGGEVLCYVY-MSQKIRIKLKSYDYMLVDKSAEKIVKTVKAAGAMVSGPIPLPTHKRIFTVNRS TFVNKKSR-EQFELSSYKRLIDIYNSTAKTVDALMKLELPSGVEVEIKVRKERVGVVSSNKMDKTITVAVKWKEKHPIYG KFVNKTKKYHAHDEK--NECGIGDTVRIMETRPLSRTKRWRLTEIIERA------------------------------- -MSRSL-KKGPYINL-KLEKKVLAMNE---SGKKA----VIKTWARASMISPDFVGHTIAVHNGNKFIPVFVTE-NMVGH KLGEFSPTRTFRGHA------G----N----KKK-------- >BARIO_Prosthecochloris_aestuarii_SK413,_DSM_271 Concatenation of 2 sequences MAIRKLRPVTPASRYLSYPEFDE-ITKS------------EP-EKSLLAPLKKSGGRNKAGRITSRH-RGGGHKRF---- YRIIDFK-R--NK-DNIPATVAAIEYDPNRSARIALLHYV-DGEKRYILAPKGLKVGEQLLSGD-K-VE-VKPGNTMPLK NIPLGTDIHNIEMKAGKGGQIVRSAGAYAVLAAK--EGDYATLKLPSGEIRKVRIECRATIGGVGNADHENIVLGKAGRS -RWL-----GVR-P-QTRGMAMNPVDHPMGGGEGKS-KSGGGRKHPKSP---WGQLAKGLKTR-NKKKASS-K-LIVRGR --------------------------------MAA-----ILGKKIGMTRIYN-EKRE---------AVPCTVIQAAPCF VSQVK----TSD----N--DGY--EAYQLSI-------GE--RVSK----------PMRGHYK----------------- ---AG-ITPGYKIAEFGK-------DLMDADL-----EL---GS-SVSV--D-M-FKEGDKVDVRGVTKGKGFAGVVKRH NFAG-GSRTHGQSDRLRA-PGSVGGS-SDPS-RTFKGMRMAGRMGSKNVKVRGLQIVKIIPESN---------------- ----------LLVIKGS-VPGVKNSYVEIV--MELKVIN-TAGAETGEVISLDDKVF----AA-KV-SEHAVYLDVKSLL ANKRQGTHKVKNRSE--------VR-GGGKKPY---------RQKGTGHAR--------QGS---SR-SG----LM---- SGGGSIFGPQ-P-HGYDLKVNRKIKRLARRSALSSKAGEG----------------R-IIVIEDF----TFE-Q------ --IKTRLVL--LPEHN--E---IINRSGRNIPVLN-I---------------RVADQASTYDILDCQT----VVMQKAAV KKIESRLAESYKEKV----VPALMERFQYKNIMMVPKLTKISINIGVG-EAASEPKLLETAMQELAQITGQKPQIRKARK AISNFKLREGQPIGCRVTLRKKYMYEFLDRFVTLAVPRIRDFRGLSN-TSFDGRGNYTLGIREQIIFPEID-----IDKV PRIQGMDISFVTT-----------------------ARTDEEAFALLSELGMPFMSRIG-K--MPVQLADQAKIE-I--- -K-D--N-VITVSGPKGTLQQQL--VP-E--VSVDIAD-GQ--ITV---TR-A--DDTKRSR-AMHGLYRMLVSNMVDGV TKGFTRKLLISGVGF--RAEMKS-DL--LALT--LGYSHQIYFKA-P-E-EVTIACP--D-PTTIEISG-IDKALVGQVA AKIRSFR------KPEPY---RGKGIKFSDEVVRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--AAIGDQIMVTVKAAVPG-G-------VVKKKDVCKAVVVRCAKEKKRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DRKYMKIVSLAPEVLMD-L--SSLSPAKGS-VKNKKRVG-RGQGSGN-GTTAGKGNKGQQSRSGYK----- -RPVS-E-GGQMPLYRRLPK-FG--FTKVNLSQIVGVEDFKQL-CNASFK---------VLG--NGE-L-G-T-A-VKI- TAHFVSKSAEEKIKQAGGEV-K---VMR--GKM---KGNA-GRGTTVTFG----------TYALKAL--EPAWITSRQIE AARVAMNRFM------KRDGKIWIRIFPDKPVTKKPAETRMGSGK---------GNPEFWVAVVKP-GRIMFEA--EG-- VSQEVATEAFRLAAKKLPIKTKF-IKAARRQKIKLRSKTRG---QGTAASPRLCVFRSVSQIYAQLVDD---V--NGATL LAVSSM-AKEN-KE------LKG-TKTEVSHTIGKQIGEK--ALAQG-ITKVIFDRNGFRYH--GRVKALAEGAREAGLV F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRIVAGLIRGKQVDQAKAILLNS---------------------------------TKAASRQVIQTLKSAVAN---YAQ LNPEDRAGDNELVVKTIFVDEGPTIKRMLPAPMGRAYRIRKRSNHLTIVVDKKLHVRKNDTVVVIAGN------DK-GKT GKVLKAYPQAC--RVI--VEGVNIRKRHVR----PS--QS-HPQ-GAIIEREFPIHASNVK------------------- ----------------------KG--------------------MGQKVNPTGFRLG--II-RDWTSRWYD------DSP V--IAEKLKQDHVIRNYV--QARLKRE---RAGIAKIVIERTT-K-HIKINIFAARPGAVVGRKGEEINNLSQELSRIVK IDVIEVIK---PEIEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRA-GAEGIRIRCAGRLGGVEIARSEQYKEGKIPL- -HTLRANVDYASVTAHTIAGAIGIKVWVYMPVTDSIADYLTRLRNAGQAKNKTTDI-PYSTQKENISKLLVEKGYIKNYT VIT----S---D----RFPFIRVELKYG---SNG-------T---FAIKEITRVSKPGRRVYEGK-DLRKYLGGLGLLIL STSKGILTDKEAREQGVGGEVLFRILAVQQKIRIKLKSYDHSLVDKWAVKIIDVVKQTDAIIFGPIPLPTKSHVYTVNRS PHVDKKSR-EQFSFSSHKRLIEIMNPTGKTIDMLMKLELPSGVDVEIKSKKTWVGKVVSDRMDKAIVVAVERRIKHPVYK KYFKRTTRLMAHDQN--NEAGIGDTVKVMECRPLSKRKTCRLVEIVEKA------------------------------- -MPRSL-KKGPFIEG-KLEKRILDMNS---REEKK----VVKTWARSSMISPDFVGHTVAVHNGKTHVPVYISE-NMVGH KLGEFAPTRTYRGHAGGKAEKG-GSAP----KRK-------- >BARIO_Prosthecochloris_vibrioformis_DSM_265 Concatenation of 2 sequences MSYPA---------------FDE-ITKS------------TP-EKRLLVPLKKSGGRNNTGRKTSRH-RGGGHRRH---- YRIIDFK-R--TK-DGVPATVASIEYDPNRSSRIALLHYN-DGEKRYILAPKGLKVGDKVESGD-K-VE-VRTGNTMPLK NIPLGTDIHNIEMKAGKGGQIVRSAGTFAVLAAR--EGDYVTLKLPSGEIRKVRVECRATIGVVGNTDHENLDLGKAGRS -RWL-----GIR-P-QTRGMAMNPVDHPMGGGEGRS-KSGGGRRHPKSP---WGQLAKGLKTR-NKKKASQ-K-LIVRGR --------------------------------MGA-----ILGKKIGMTRLYN-EKRE---------AVPCTIIQAGPCF VTQVK----SAG----I--DGY--DAYQVGI-------GE--RVTK----------PMLGHYK----------------- ---AG-VAPGYMTAEFDT-------SMFDGEL-----TA---GS-PVLV--E-S-FTEGEIVKVQGVSKGKGFAGVVKRH NFGG-GQRTHGQSDRLRA-PGSIGGA-SDPS-KTFKGTKMGGRMGSDTITVRNLQVIKIMPESS---------------- ----------LIMVKGS-VPGPKNSYVRIV--MELKVLT-TAGTESGEVVTLRDDIF----GA-EV-SEHAVYLDVKSIL ANRRQGTHKSKTRAE--------VR-GGGRKPY---------RQKGTGNAR--------QGS---TR-SP----LM---- VGGGTIFGPT-P-HGYDQKVNKKVKALARRSAFSSKAQDG----------------R-ILVVEDF----KLD-E------ --IKTKLML--TPEYN--V---IITRSGKNIQTVN-I---------------MSAEKASTYDILNSHT----VLFQKAAL KKIEARLQTLYHEKV----VSALTERFKYDNVMNVPKLKKISINIGVG-EAASEPKLLETALQELSQITGQKPQIRKSKK AISNFKLREGQAIGCRVTLRRKAMYEFFDRFVSIAVPRIRDFRGLPD-TSFDGRGNYTVGVREQIIFPEID-----IDKV PRIQGMDISFVTS-----------------------ATTDEEAFVLLTELGMPFMSRIG-K--MPIALAKEAKLE-I--- -S-E--G-NLRVSGPKGVLEQAL-VEE----VKVLQEE-GL--VKV----E-R--INDKRSR-AMHGLYRMLLSNMIEGV TKGFTRKLEIAGVGF--RAEMKG-DL--LALT--LGFSHMIYFKA-P-E-GVKLETP--D-PVTVLVSG-IDKALIGQVA AKIRSFR------KPEPY---RGKGIKYEGEVIRRKEGK----------MIQKETNLVVADNSGAKKVRCIHVFG-TGRR Y--ASLGDQVIVSVKAAVPG-G-------VVKKKEVCKAVVVRCAKELRRKDGSYIRFDENAVVLLN-AQGE-PRGTRIF GPVARELR-DRKYMKIVSLAPEVLMD-L--SSLRPAKGA-VKTKKRVG-RGQGTGN-GTTAGKGNKGQQSRSGYK----- -RPIN-E-GGQIPVYRRLPK-FG--FTPVNLSQIISILDLKNL-CHASFK---------VLG--NGE-I-S-V-A-ITI- TAHAFSKSAEEKIVAAGGSV-K---TQR--GRM---KGNA-GRGTDVSFG----------SFGLKAI--EPAWITSRQIE AARVAMNRYM------KRDGKIWIRIFPDKPVSKKAAETRMGSGK---------GAPEFWVAVVKP-GRIMFEA--DG-- VSKEIATEAFRLAAKKLPIKTRF-IKASRRQKIKDRSRAAV---AGTAVKPRLCIYRSLSQIYAQLIDD---S--GSTTI LAVSSM-SKEN-KE------LKG-AGVEVCRTVGRQLGEK--AMAKG-ITTVVFDRNGFRYH--GRVKALADGAREAGLI F--------------------------------------------------------------MQ-AKAILRHTPTSPRK MRLVAGLVRGKAVDQAKAILLNS---------------------------------TKAASRNALQTLKSAVAN---YAQ LNPDERVGDQELFVKSVFVDEGATLKRMLPAPMGRAYRVRKRSNHLTIVVDRKVHVKKNDMVTVISGN------DK-GKS GKVLRVYPVKG--RVI--VEGVNIRKRHMR----PT--QS-SPQ-GQIIEREFPVHASNVK------------------- ----------------------KG--------------------MGQKVNPTGFRLG--II-RDWTSRWYD------D-S P-VISEKIKQDQVIRNYV--QTRLKRE---KAGIARIIIERTN-K-NIRINIYAARPGAVVGRKGEEINNLSQELGRIVK IDVVEVVK---PEIESQLIGENIAYQLENRVSFRRAMKQAIQTAMRA-GAEGVRIRCAGRLGGAEIARAEQYKEGKIPL- -HTIRANVDYASVTAHTIAGTIGIKVWVYMPVTDSIADYITRLRNAGRAKNKTTDI-PYSKLRENISQLLLEKGYIKGFT VIT----T---E----KFPFIRVEMKYT---AAG-------V---PSIKEITRVSRPGRRMYEGK-DIKKYLGGLGLYII STSKGVITDKEAREQGVGGEILFRIYAVQQKIRIKLKSYDHSLVDKWASRIIDVVKETDAIIFGPIPLPTKSHVYTVNRS PHVDKKSR-EQFSFSSHKRLIEIMNPTSRTIDLLMKLELPSGVDVEIKSKKSWLGKVVSDKMDKAIVVAVERRVQHPVYK KYFRKTTRIMAHDEN--NEAGIGDLVKVIECRPISKRKSCRLVEILEKA------------------------------- -MPRSL-KKGPYIDI-KLERRVLDMNS---RGEKK----VLKTWCRSSMISPDFVGHTIAVHNGKTHVPVYVSD-NMVGH KLGEFAPTRTYRGHAGGKAEKG-GAAP----KRK-------- >BARIO_Salinibacter_ruber_DSM_13855 Concatenation of 2 sequences MSIKKRKPTINSQRQYSVDDKED-ITTT------------DP-ERSLLEPLPNSGGRNNQGRMTMRY-RGGGHKRR---- YRKIDFK-RR-DK-DGIPATVKTIEYDPNRSARISLLAYA-DGEKRYIITPDGLEVGDTVMNGP-Q-AQ-AEVGNCLPLT SIPLGTKVHCVEMTPEKGAQMVRAAGTHAQLTAR--EGDYATLELPSGETRLVPSKCRATVGTTSNVEHENVVLGKAGRK -RWL-----GRR-P-RTRGVAMNPIDHPMGGGEGLK-S--GGH--PRSR---EGVPAKGYKTR-KRNKESN-K-YIIRRR --------------------------------MSS---G-LIGKKVGMTSVFD-DEGN---------NVACTVVEAGPNV VTQVK----SEG----R--DGY--SAVQLGF-------DN--VVTQ----------AMLGHFK----------------- ---AG-CPPKRMLSEFRD---------FGDDV-----DL---GD-VVRV--QDL-FQEDERIDVVGVSKGKGFQGVVKRH GFSGVGMMTHGQSDRQRH-PGSIGAS-ADPS-RVFKGVRMAGQTGGERTKIQNLRVVRILADQN---------------- ----------AILIHGS-VPGPKSEYVELH--MDVEIYQ-EDGVESGETAALDPTVF----DI-EP-NDHIIWLDVKRIQ AHQRQGTSKTKERGE--------VR-GSGRKLY---------RQKGTGNAR--------VGD---AQ-SP----IR---- RGGGRAHGAR-P-RDYAHDLNQKEKRLARRSALSYKAAND----------------N-IQVIENF----SLD-R------ --PDTRLLA--TAEVE--R---EVYLSSQNLPDVN-V---------------QEVQSINTVDILDADV----VLLQEGAL DWLTPRLQKQYQDEV----RPSLTDQFGYENPMEVPRLEKICVNRGVG-EVSENQKALDQAVEEMRKITGQHPTIRRAKR SIASFDVREGMPVGVKVTLREARMYEFFDRLVTLALPNIRDFRGVPD-RSFDGRGNYTLGIDEQIIFPEID-----VDNV DRIDGMDITFVTD-----------------------AETDEESYALLKGLGMPFMARIG-D--NPIPFGDEVTVS-V--- -D-D-HN-VVTIEGPKGTLTEQI--DP-E--MTLDIAD-DH--VVV---RR-P--TNQKRHR-SLHGLSRSLIVNMVEGV TEGYKKELKIIGVGY--RAQMSD-ET--LEIA--LGYSHPIYFLP-P-S-DVAVSVD--S-DDIIIVEG-IDKELVGQVA AKIRSLR------PPEPY---KGKGVRYVDEHVPLKAGK----------MIQQETRLNVADNSGAKEAQCIRVLS-SGRR Y--AGIGDQIVVSVKSAIPS-G-------EINKGDVSRAVVVRTAKETRREDGTYIRFDENAAVLIN-QEEE-PVGTRVF GPVAREVR-EKQFMRIVSLAPEVLMD-L--SNLKPAEGA-TQAGQRLG-RGEGSGRGGHSSTRGTKGQSSRSGSG-TR-- -PIWF-E-GGQTPLFQRVPK-HG--FNNANVKRLVTPEVLADL-GVVRVK---------ILG--DGD-L-F-D-A-LEV- KAHAFSESARQKIKQAGGSV-K---VQRNQGLK---RNKYAVKGTRLSFG----------DYGLKSL--EEGEVNSRQLE AARVAINRYL------KRDGKVWIRVFPDKPKTKTPAETRMGKGK---------GEPEHFVAPVQP-GNVIFEV--GG-G ADEESAREALRLGKHKLPLKTKF-VKVERRQRIHDSIRESM---FGTSVRPRLSVYRSNEHIYAQLVDD---M--EGHTL TSASTL-ADDV---------EGE-TPTEESRSVGELLAER--AEDAG-IDKAVFDRGGYKYQ--GRVRALAEGARDGGLQ L--------------------------------------------------------------MQ-ARAVRRHIRSSPLK MRRVINLVRDRSVPEAVAILDYM---------------------------------PQKVTGVVEKTIRSAVYN----LM DQHDERFDEGALKLKEIRADEGPTFQRHQARARGRAAPIRKRTTHLKVVVAVMVMLNKTITSAKSAGE------DRAGYV GKVLKVFPDEQ--RVI--VEGVNVRVFHEK----PS--RS-NRE-GGRTEREAPIHVSNVN-PIDSN--------GE--S --TRIGRKK---VE--------DPWVR---YAKTTG---EEL--MGQKTHPIGFRLG--AI-RGWDSNWYS------E-T N--FQDKLVEDEELRRYL--HTRLK-----RAGLSRAVIERTP-E-RVILTLHTSRPGVVIGRGGSEVEKLKGELETLIQ INISEIKR---PELDATLVAKNIVQQLEGRISFRRAMKQAMQAAMRM-GAEGVRIRAAGRLGGAEMGRTEEYMEGRVPL- -HTIRADIDFAQETALTIYGTIGVKVWIHSGISDPVSNYMAQLRNAQEAEQTYVDI-PASKLKRAMTQILLEKGYIKNFV NID----D---E----KQGLLRVYLKYD---EYD-------Q---PAIRMLERVSRPGRREYADSDNLPEVKNGLGIVIL STSRGVMSDKEARRFGVGGEVLAKVFAAQQDIRIKLKSYDHTLIDKSAEKIIRTVKSTGAVVSGPVPLPTEKKIYTVLRG PHVDKKSR-EQFERRHHKRLIDILSSSSDTVDSLMQLELPSGVDVEIKVRKERIGVVESAKMDKTITVSVRRQMKHPMYG KYLERSSTFMAHDEG--DEANEGDTVRIMETRPISKNKRWRLVEIIERA------------------------------- -MPRSL-RKGPYVYY-KLQRKVDALNE---SDEKK----VIKTWSRDSIITPDFVGHTFAVHNGHQFIPVYVTE-NMVGH KLGEFAPTRTFTEHS------QAKVDQ----RIR------KP >BETA_Acidovorax_avenae_citrulli_AAC00-1 Concatenation of 2 sequences MAVIKMKPTSPGQRAVVKVTRDH-LYKG------------EA-FAALLEPQHQKSGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN--K-DAIPAKVERIEYDPNRTAHIALVCYA-DGERRYIIAPRNLEVGATIVSGS-E-AP-IRVGNTLPIR NIPVGSTIHCIELKPGAGAQIARSAGTSATLLAR--EGTYAQVRMRSGEVRRIHIECRATIGEVANEEHSLRQLGKAGVK -RWM-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-G--EGR-HAVDP---WGNLTKGYRTR-NNKR-TQ-V-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------AVPVTVVDVSNNR VTQVK----TQE----N--DGY--VALQVTF-------GS--RVTK----------PEAGHLK----------------- ---AG-VEAGEIIREFRV------TAETAGKY-----AT---GA-AVPV-AD-V-FSVGQKVDVQGTSIGKGYAGTIKRH NMAS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDATTTTQNLDVIRVDEARQ---------------- ----------LLLIKGA-IPGSKGGFVTVR--MQLELLN-DQGQAA-SKIDVPETVF----DR-QY-NEDLIHQIVVAYR ANARQGTRAQKDREQ--------VR-HSTKKPF---------KQKGTGNAR--------AGM---TS-SP----LW---- RGGGRIFPNL-PEENFTQKINKKMYRAGMASILSQLAREG----------------R-LAVVDSL----KVE-T------ --PKTKMVI--SDEVD--E---NLYLASRNLKNVF-V---------------VEPRYADPVSLVHYKK----VLVTKGAI DKLKARLQQHYREKI----VPELTKQFGYTSPMEVPRLTKITLNMGVS-EAVSDKKVMDNAVADLTKIAGQKPVVTKAKK AIAGFKIREGQAIGCMVTLRGVQMYEFLDRFVTVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKSDEEAKALLAGFRFPFMSRVG-K--MPVAIPNGVDVT-I--- -T-E--E-QISVKGSGGTLSVAQ--NR-L--VKIVNKD-GK--LSF----E-P-ADESREAN-AMSGTIRQLVNNMVVGV SKGFEKKLNLIGVGY--KAQASG-AK--LNLA--VGYSHPVNFDM-P-A-GITVATP--T-PTEIVIKG-ADRQRVGQLA AEIRAVR------PPEPY---KGKGIRYSDEKVTIKETK----------MIQTKSRLDVADNTGAKSVLCIKVLG-SKRR Y--ASVGDIIKVSIKEAAPR-G-------RVKKGEVYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NSIKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVTLSTLVDLAALKSA-GVVGVK---------VIK--SGE-L-T-K-A-VKL- NGIGATAGAKAAIEAAGGSL-K---EQK--GRN---TGVA-TRGNSVAFG----------DFGLKCT--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISTKPAEVRMGNGK---------GNPEYYVAEIQP-GKIVFEI--VG-- VPEELAREAFRLAAAKLPLRTTF-VKKEQRLRRSRQTRIRI----AQQGVVRLTVNRTNLHIYASVISE---D--GSRVL ASASTA-EAEV-RKEL-GGSGKG-GNAAAAQMIGKRIAEK--AKAAG-IEKVAFDRAGFAYH--GRVKALAEAAREAGLQ F-------------------------------------------------------------MSE-TRAVLRGVRLSVDK GRLVADLIRGKKVDQALNILTFT---------------------------------QKKAAVIVKKVLESAIAN----A- EHND-GADIDELKVKTIYVEQGTTLKRFTARAKGRGNRISKPTCHVYVTVGNMNKIRKGDEVIVLTGR------DK-GKR GTVSLRKDDSY---LV--IDGINLVKKHVK----PN--PMKGTT-GGIVEKAMPIHQSNVA-IFNAAT-------GK--A --DRVGIKV---QA--------DGRVR---VFKSSG---AEI--MGQKIHPTGFRLA--VS-RNWASRWYA------NNR D--FAGMLAEDIKVREYL--KAKLK-----NAAVSRILIERPA-K-NARITIYSARPGVVIGKKGEDIENLKKELASRVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGTSEAFTTYGVIGLKVWVYMSMSDPIADLLTRIRNAQMVSKATVSV-PSSKVKIAIAQVLKDEGYIDGFE VKS----E---G----NKSELEISLKYY----AG-------R---PVIERIERVSRPGLRVYKGRDSIPQVMNGLGVAIV TTPKGVMTDRKARATGVGGEVLCYVAMSKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSDKREKTVTVLVERRVKHPIYD KIVIKSSKYHAHDEN--SEYKLGDTIEITESRPLSKTKNWVATRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLLAKVEKAVA---TKDKK----PVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYITD-QMVGH KLGEFALTRTFKGHP------A---DK----KVQ------KK >BETA_Acidovorax_sp_JS42 Concatenation of 2 sequences MAVIKIKPTSPGQRGAVKISRDH-LYKG------------EA-FAGLLEPQFQKAGRNNNGHITTRH-KGGGHKHH---- YRVVDFR-RN--K-DAIPAKVERIEYDPNRTAHIALVCYA-DGERRYIIAPRNLEVGATIVSGS-E-AP-IRVGNTLPIR NIPVGSTIHCIELKPGAGAQIARSAGTSATLLAR--EGVYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRQLGKAGVK -RWM-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-G--EGR-HAVDP---WGNLTKGYRTR-NNKR-TQ-V-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------AVPVTVVDVSNNR VTQVK----TQE----N--DGY--VSLQVTF-------GS--RVTK----------PEAGHLK----------------- ---AG-VEAGEIIREFRV------TPEVAGKY-----AA---GA-AVPV-AD-V-FAVGQKVDVQGTSIGKGFAGTIKRH NFGS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKKMTGHLGDVTVTTQNLDVVRIDEARQ---------------- ----------LLLIKGA-VPGSKGGFVTVR--MQLELLN-EQGQAA-SKVDVPETVF----DR-QY-NEDLIHQIVVAYQ ANARQGTRAQKDREQ--------VK-HSTKKPF---------KQKGTGNAR--------AGM---TS-SP----LW---- RGGGRIFPNL-PEENFSQKINKKMYRAGMASILSQLAREG----------------R-LAVVDSL----KLD-T------ --PKTKMVI--ADEVD--E---NLYLASRNLKNVF-V---------------TEPRYADPVSLVHYKK----VLVTKGAI DKLKARLQEIYRDKI----APELVKQFGYTSPMQVPRLTKITLNMGVS-EAVADKKIMDNAVADLTKIAGQKPVVTKAKK AIAGFKIREGQAIGCMVTLRGAQMYEFLDRFVTIALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKTDEEAKALLTAFRFPFMSRVG-K--SPVSIPAGVDVS-I--- -K-D--D-QISVKGAGGVLSLAQ--NA-L--VKVSNNE-GK--LSF----E-P-VNDSREAN-AMSGTVRQLVNNMVVGV SKGFEKKLTLIGVGF--KAAASG-NK--LNLA--IGFSHPVNFEM-P-T-GITVATP--T-PTEIVIKG-ADRQVVGQLA AEIRAVR------PPEPY---KGKGIRYADEKVTIKETK----------MIQTESRLDVADNTGAKSVLCIKVLG-SKRR Y--ASVGDIIKVSVKEAAPR-G-------RVKKGEVYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLN-SKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NSIKPADGA-KHAARRVG-RGIGSGL-GKTAGRGHKGQKSRSGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSISLTALVDVLALKNA-GLVGVK---------VIK--SGE-I-S-K-A-VKL- SGITATAGAKAAIEAAGGSL-K---EQK--GRN---TGVA-TRGNSVAFG----------DFGLKCT--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISTKPAEVRMGNGK---------GNPEYYVAEIQP-GKVVFEI--VG-- VPEELAREAFRLAAAKLPLRTTF-VKKEQRLRRARQTRIRI----AQQGVARLTVNRTNLHIYASVISG---D--GSKVL ASASTA-EADV-RKSL-GGSGKG-GNAAAAQIIGKRIAEK--AKAAG-VEKVAFDRAGFAYH--GRVKALADAAREAGLQ F-------------------------------------------------------------MSE-TRAVLRGVRLSVDK GRLVADLIRGKKVDQALNILAFT---------------------------------QKKAAVIVKKVLESAIAN----A- EHND-GADIDDLKVKTIFVEQGTTLKRFTARAKGRGNRISKPTCHIYVTVGNMNKIRKGDEVIVLTGR------DK-GKR GTVSLRKDDSH---LV--IEGINLVKKHVK----PN--PMKGTT-GGIVEKAMPIHQSNVA-IFNAAT-------GK--A --DRVGIKV---QA--------DGRVR---VFKSSG---AEI--MGQKIHPTGFRLS--VS-RNWASRWYA------SNR D--FAGMLAEDIKVREYL--KAKLK-----NAAVSRILIERPA-K-NARITIFSARPGVVIGKKGEDIENLKKELATRVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGTSEAKTTYGVIGVKVWVYMSMSDPIADLLTRIRNAQMVSKATVSV-PSSKVKVAIAQVLKDEGYIDGFE VKS----E---S----GKTELEITLKYY----AG-------R---PVIERIERVSRPGLRVYKGCGSIPQVMNGLGVAIV TTPKGVMTDRKARATGVGGEVLCYVAMSKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSDKRAKTVTVLVERRVKHPIYD KIMIKSSKYHAHDEN--GEYKMGDTIEITESRPLSKTKNWVATRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLVAKVEKAIA---TKDKK----PVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYVTD-QMVGH KLGEFALTRTFKGHP------A---DK----KVQ------KK >BETA_Azoarcus_sp_BH72 Concatenation of 2 sequences MALVKLKPTSAGRRGMVKVVNPD-LYKG------------RP-HDALTEKKTSKAGRNNSGRVTVRH-QGGGHKMH---- YRVIDFR-RN--K-DGIAAKVERIEYDPNRSANIALLCYA-DGERRYIIAPRGVEVGQQLMSGA-E-AP-IKAGNALPIR NIPVGSTIHCVEMMPGKGAQIARAAGTSVQLLAR--EGAYAQLRLRSGEIRRVHVECRATIGEVGNEEHSLRKIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT-G--EGR-VPVSP---WGTPAKGYRTR-RNKR-TD-N-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFA-DDGR---------SIPVTVLDVSDNK VTQIK----TPE----A--DGY--SAVQVAF-------GK--RVVK----------PIAGHLK----------------- ---AG-VEPSRVLKEFRV---------EPEGL-----AS--LGD-QVSV--E-I-FSVGQKVDVTGVSIGKGFSGPIKRH NFSS-NRASHGNSVSHNS-PGSIGMA-QDPG-RVFPGKRMAGQYGAVQRTTLGLEVVRVDAERQ---------------- ----------LLLVKGA-VPGAKGGDVVVR--MELKLLN-EQGQPA-STLDASDVLF----AR-EY-NEALVHQVVTAYL ANARSGNRAQKGRSE--------IA-KSTRKPF---------RQKGTGNAR--------AGM---AS-SP----LW---- RGGGKIFPNS-PDENFSQKVNRKMYRAGVAAILSQLARED----------------R-LAVVDNF----SVE-A------ --PKTRLVI--TDGLD--E---NLFLSSRNLHKVL-V---------------LDVHETDPVSLVRFPK----VLVTKGAL AKMEARLQQFYKDEV----VPQLLKQFGYKSVMEVPRITKITLNMGVG-EAVGDKKVLENAIGDMTKIAGQKPVATKARK SIAGFKIREGYPIGCMVTLRGPRMFEFFDRLVTVALPRVRDFRGIAA-KGFDGRGNYNLGVKEQIIFPEIE-----YDKI DALRGMNISITTT-----------------------AKSDDEARALLAAFKFPFMSRVA-K--NPVVIPKGVEVS-I--- -S-A--A-EIAIKGPLGTLVRPQ--HP-A--VTVEQDG-EA--LVC----K-A--RDGVNAR-AMSGTVRALLNNMVVGV SKGFERKLLLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-A-GVKVETP--S-QTEIVIKG-VDKQQVGQVA AEVRAYR------APEPY---KGKGVRYSDEVVVLKETK----------MIQMQSKLDVADNTGARSVMCIKVLG-SKRR Y--ASIGDIIKVTVKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGSLVKFDNNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLMR-L--NTIKPGAGS-KSAGKRVG-RGIGSGL-GKTCGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FVSVRLSELVDLLVLKQA-GVIAAK---------VVL--SGA-I-S-K-K-VVL- RGIAATAGARAAIEAAGGSC-K---EQK--GRN---TGLA-TRGTKVSFG----------DFGLKAI--ARGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--DG-- VDEALAREAFRLAAAKLPLETVF-VKKETRLRRARKTRAKL----AELKAVRLAVFRTNCHIYAQVISG---C--GSRVL AAASTV-ESAV-RSQV----ANG-GNKQAAEVVGKLIAER--AKAAG-IETVAFDRSGFLYH--GRVKALAEAAREGGLK F--------------------------------------------------------------ME-TKAILRGVRLSAQK GRLVADLVRGKSVDQALNILAFS---------------------------------PKKGAKIIRKVVESAIAN----A- EHND-GADIDALKVKTIYVEEGTTLKRFTARAKGRGNRILKPTCHVFVTVGEMNKIRKGDEVVVLAGK------DR-GRR GAVLRRVDDER---VV--VEGVNRVKKHVR----PN--PLKGEV-GGIVEKEMPIHVSNVA-LFNPAA-------QK--A --DRVGIKV---LE--------DGKVR---FFKSNG---ELV--MGQKIHPTGFRLA--VT-RDWGSRWFA------SSR D--FSKMLHEDLKVRDYL--KKRLA-----HASVGRVVIERPA-K-NARVTLFSARPGVVIGKKGEDIEALKRDLQKIVH VNIEEVRK---PEIDAKLIADSIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGAEIARTEWYREGRVPL- -HTLRANIDYGVSEAQTTYGVIGIKVWVFMSMSDPIADMLTRIRNGQQAQKASVTM-PSSKVKVAIAKVLQDEGYIEGFS VRE----G---E----GKAVLDVALKYY----AG-------R---PVIERIERVSRPGLRVYKGTDDLPRVMNGLGVAIV STPKGVMTDRAARASHVGGEVICLVAMQNQKIRIRLKAFDYRLIDQSALEIVDTAKRTGAVVRGPVPLPTRIERFNLLRS PHVNKTSR-DQMEIRTHQRLMDIIDPTDKTVDALMKLDLPAGVDVEIKLRRALIGRVVSDKMQKTVTVLVERRVKHPLYG KIITRSAKYHAHVED--GGAGEGDLVEIEECRPISRTKTWRVTRVVEKA------------------------------- -MARSI-KKGPFIDA-HLLKKVDAARA---SNDKR----PIKTWSRRSTVLPDFVGLTIAVHNGRQHIPVYVSE-NMVGH KLGEFALTRTFKGHA------A---SK----KAK-------R >BETA_Azoarcus_sp_EbN1 Concatenation of 2 sequences MALVKLKPTSAGRRAMVKVVNAD-LYKG------------RP-HAALVEKQSKNAGRNNSGRITVRH-QGGGHKQH---- YRLVDFR-RN--K-DGIAARVERVEYDPNRSANIALICYA-DGERAYIIAPKGLEVGQTVLSGP-E-AP-IKAGNVLPIR NIPVGSTIHCVELMPGKGAQIARAAGTSVQLLAR--EGAYAQLRLRSGEVRRVHVECRAAIGVVGNEEHGLRKIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT-G--EGG-VARSP---WGQPAKGYRTR-SNKR-TD-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFA-EDGR---------SVPVTVLDVSNNR VTQIK----TPE----S--DGY--AAVQVTF-------GK--RVGK----------PLAGHLK----------------- ---AG-VEAGHMLKEFRV------ETEQVAGF-----KA---GD-VVGV--D-L-FAVGQKVDVTGTSIGKGFSGVGKRH NFSS-NRASHGNSVSHNA-PGSIGMA-QDPG-RVFPGKRMAGQYGNTTCTTQGLEVVRVDVERQ---------------- ----------LLLVKGA-VPGSKGGDVIVR--MELKLLN-DQGAQS-ATLQASDALF----GR-DY-NEALIHQVVVAYM ANARSGNRAQKGRAE--------VS-KSTRKPW---------RQKGTGRAR--------AGM---AS-SP----LW---- RGGGRVFPNS-PEDNFSQKLNRKMYRAGVASILSQLARED----------------R-LAIVENF----SVE-A------ --PKTRLVI--TDEFD--E---NLFLSSRNLHKVL-V---------------LEVSETDPVSLVHYDR----VIVTKGAL AKMEARLQEFYKETV----APDLLKQFGYKSVMEVPRITKITLNMGVG-EAVGDKKILEHAVGDMVKIAGQKPVVTKARK SIAGFKIRDGYPIGCMVTLRGAKMFEFLDRLVTVAMPRIRDFRGIGG-KGFDGRGNYNLGVKEQIIFPEIE-----YDKI DALRGMNISITTT-----------------------AKSDQEARALLVAFKFPFMSRVA-K--NPVAIPQGVEIT-I--- -G-A--D-EVSVKGPLGAVKQYI--GN-A--VTLERDG-DA--LVC----K-A--REGANSR-AMSGTVRALVNNMVTGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLT--LGFSHPVVHQM-P-A-GVKVETP--T-QTEIVIKG-IDKQQVGQVA AEVRAYR------EPEPY---KGKGVRYSDEVVVLKETK----------MIQMQSRLDVADNTGARSVMCIKVLG-SKRR Y--AGIGDIIKVTVKDAAPR-G-------RVKKGDIYSAVVVRTAKGVRRPDGSLVKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMR-L--NTIKPGAGS-KSAAKRVG-RGIGSGL-GKTCGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FVSVRLSELIDLLVLMQA-GVVPAK---------VVL--SGT-I-G-R-K-ITL- RGIGATKGALAAIEAAGGSV-K---EQK--GRN---TGIA-TRGAKVSFG----------EFGLKAI--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--DG-- VDETLAREAFRLAAAKLPLETVF-VKKEVRLRRARKTRAKI----AELKSVRLTVFRTNSHIYAQVIDG---S--GSRVL AAASTV-EADV-RSQL----PNG-GNKQAAQVVGKLIAER--AKAAG-VEAVAFDRAGFQYH--GRVKALAEAAREGGLK F--------------------------------------------------------------ME-TRAILRGVRLSAQK GRLVADQVRGRPVDQALNILAFS---------------------------------PKKGAQIIRKVMESAIAN----A- EHND-GADIDTLKVKTIYVEEGMSLKRFAARAKGRGARILKPTCHIYVTVGEMNKIRKGDEVVVLAGK------DR-GRR GVVLSRVDDER---LL--VEGVNRVKKHVR----PN--PLKGEV-GGIVEKEMPLHISNVA-LFNPAA-------QK--G --DRVGIRV---LE--------DGKVR---FFKSNG---ELV--MGQKIHPTGFRLA--VT-RDWNSRWFA------SSG D--YSRMLHEDLKVRDFL--KKRLA-----HASVGRVVIERPA-K-NARITLFSARPGVVIGKKGEDIELLKRELQKIVH VNIEEVRK---PEVDAKLIADSIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGAEIARTEWYREGRVPL- -HTLRADIDYGVSEAKTTYGIIGIKVWVYMSMSDPIADMLTRIRNGQQAQKVSVSM-PCSKLKVAIAKVLQDEGYIDGYS IRE----A---G----GKPELDVALKYY----AG-------R---PVIERIERVSRPGLRVYKGSGDLPRVMNGLGVAIV STPRGVMTDRAARAGRVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSALEIVDTAKRTGAVVRGPVPLPTRIERFDLLRS PHVNKASR-DQFEIRTHQRLMDIIDPTDKTVDALMKLDLPAGVDVEIKLRRALVGRVVSDKMQNTVTVLVERRVKHELYG KVITRSAKYHAHVED--GGAAAGDLVEIEECRPISKTKSWRVAKVLEKA------------------------------- -MARSI-KKGPFVDA-HLLKKVDAVRT---SNDKR----PIKTWSRRSTVLPDFVGLTIAVHNGRQHVPVFVSE-NMVGH KLGEFALTRTFKGHA------A---SK----KAK------R- >BETA_Bordetella_avium_197N Concatenation of 2 sequences MALVKVKPTSAGRRGMVKVVSPN-LHKG------------AP-HAALLEKKIRGSGRNNNGHITIRH-RGGGHKQH---- YRVVDFR-R--NK-DGIPAKVERLEYDPNRTAHIALLCYA-DGERRYIIAPRGLEVGATLISGI-E-AP-IRAGNTLPIR NIPVGTTIHCIEMIPGKGAQMARSAGASAVLMAR--EGTYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRQIGKAGAM -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT----GEAREPVSP---WGTPSKGYKTR-RNKRTNN---MIVQRR --------------------------------HRL---G-LVGRKVGMTRIFT-EEGE---------SIPVTVLDVSNNR VTQVK----SLE----S--DGY--AAIQVTY-------GN--RVTK----------AEAGHFK----------------- ---AG-AEAGSILKEFRL------DPTRAAEF-----TA---GS-VIAV--ESV-FEAGQQVDVTGTTIGKGFAGTIKRH NFGS-QRASHGNSRSHRV-PGSIGQA-QDPG-RIFPGKRMAGHLGDVTRTVQNLDVVRVDVERG---------------- ----------LLLVKGA-VPGHAGGDVIVR--MDLKLLN-DQGQA--ATFSAPDTIF----GR-DF-NEALVHQIVVAYQ ANARSGNRAQKDRAE--------VK-HSTKKPW---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRAFPNS-PEENFSQKVNKKMYRAGIRSILSQLARED----------------R-IAVVDTF----SLE-S------ --PKTKLII--TDTVD--E---NVYLATRNLPHVA-V---------------VEPRYADPLSLIHYKK----VLITKPAI AQLESRLQDFYKSKV----AVDLQAKFGYKSVMEVPRITKITLNMGVS-EAVADKKVIEHAVSDLTKIAGQKPVITKTRK AIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAIALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTS-----------------------AKTDEEAKALLTAFSFPFMSRIA-K--YPVELPKGVEAS-I--- -Q-Q--D-QITVKGPLGTLVQAL--TG-D--VNIVEDA-GK--LTF----A-A--ANDRHAN-AMSGTVRALVANMVTGV SKGFERKLTLVGVGY--RASVQG-EA--VKLQ--LGFSHDILHKL-P-A-GIKAECP--T-QTEIVIKG-ANKQVVGQVA AEIRAYR------EPEPY---KGKGVRYADERVVIKETK----------MIQMQTTLDVADNTGARAVMCIKVLG-SKRR Y--AGIGDIIKVSVKDAAPR-G-------RVKKGEIYNAVVVRTAKGVRRKDGSLIRFGGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLIQ-L--NSLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTPVRLSDLIDVQALKAA-GVVGAK---------VIK--SGE-L-S-R-K-VVL- RGITATAGARAAVEAAGGSL-K---EQK--GRN---TGLA-TRGAQVSFG----------EFGLKAT--GRGRLTARQIE AARRAINRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--EG-- VSEELAREAFRLAAAKLPISTTF-VKKVTRLRRAVPTRRKI----TQLGVHRLSVFRSNQHIYANIISP---E--GDRVV VSASTL-EAEV-RTQLAGQSGAG-GNAAAAALIGKRVAEK--AKAAG-IELVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-TTAIIRGVHISAQK TRLVADLIRGKSVAQALNILTFS---------------------------------PKKAAVILKKAVESAIAN----A- EHND-GADIDELKVTTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGAMNKILKGDEVIVLTGR------DK-KRR GVVLARVDADH---VL--VEGVNVVKKHQK----AN--PMANNP-GGIVEKTLPIHISNVA-LFNPAT-------GK--A --DRVGFKE----E--------DGKVR---VFRSNG---AAV--MGQKIHPTGFRLA--VT-RNWSSRWYA------DDK D--FGGMLAEDIRVREYL--KKKLK-----SASVGRVVIERPA-K-NARITVYSARPGVVIGKRGEDIESLKADLQRLVH VNIEEIRK---PETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLKANIDYGTSEAHTTYGVIGIKVWVYMSMSDPIADMLTRIRNAQQVDKTTVNM-PSSKLKVAIATVLKDEGYIDSFE VKG----S---Q----AKPELEITLKYY----AG-------R---PVIERIERVSRPGLRIYKGRSNIPQVMNGLGVAIV STSRGVMTDRKARANGVGGEVLCYVAMKNQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAVVRGPVPLPTRIRRYDVLRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMRLDLPAGVDVEIALQRTLVGKVVSNKMDKTVVVLVERRVKHPIYG KIVMRSAKYKAHDES--NQYNEGDTVEIAEGRPISRSKAWRVVRLVEAA------------------------------- -MSRSI-KKGPFVDA-HLTKKVEAAVA---GKDKK----PIKTWSRRSTILPEFIGLTIAVHNGRQHVPVYINE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------R >BETA_Bordetella_bronchiseptica_RB50 Concatenation of 2 sequences MALVKVKPTSAGRRGMVKVVSPK-LHKG------------AP-HAALLEKKTRGSGRNNNGHITVRH-RGGGHKQH---- YRVVDFR-R--NK-DGIPAKVERLEYDPNRTAHIALLCYA-DGERRYIIAPRGLEVGATLISGI-E-AP-IRAGNTLPIR NIPVGTTIHCIEMIPGKGAQMARSAGASAVLMAR--EGTYAQVRLRSGEVRRVHIQCRATIGEVGNEEHSLRQIGKAGAM -RWR-----GVR-P-TVRGVAMNPIDHPHGGGEGRT----GEAREPVSP---WGTPAKGFKTR-RNKRTNN---MIVQRR --------------------------------HRL---G-LVGRKVGMTRIFT-EDGE---------SIPVTVLDVSNNR VTQVK----SLE----S--DGY--AAIQVTY-------GT--RVVK----------PQAGHYK----------------- ---AG-AEAGSILKEFRL------DPARAAEF-----AA---GA-VIAV--E-SVFEAGQQVDVTGTSIGKGFAGTIKRH NFGS-QRASHGNSRSHRV-PGSIGQA-QDPG-RIFPGKRMSGHMGDVTRTVQNLDVVRVDAERG---------------- ----------LLMVKGA-VPGHAGGDVIVR--MDLKLLN-DQGQA--ATFSAPDTIF----GR-DF-NEALVHQIVVAFQ ANARSGNRAQKDRAE--------VK-HSTKKPW---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRAFPNS-PEENFSQKVNKKMYRAGIRSILSQLARED----------------R-VAVVDTF----TLE-S------ --PKTKLII--TDNVD--E---NVYLATRNLPHVA-V---------------VEPRYADPLSLIHYKK----VLITKPAI AQLESRLQEFYKSKV----VADLQAKFGYKCVMEVPRITKITLNMGVS-EAVADKKVIEHAVSDLTKISGQKPVVTKTRK AIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLTAFSFPFMSRIA-K--YPVELPKGVEAS-I--- -Q-P--D-QITVKGPLGTLVQSL--TG-D--VNVAQED-GK--LTF----V-V--ANDRHAN-AMSGTLRALVANMVTGV SKGFERKLNLVGVGY--RAQIQG-DA--VKLQ--LGFSHDVVHQL-P-A-GVKAECP--T-QTEIVIKG-PNKQVVGQVA AEIRKYR------EPEPY---KGKGVRYADERVVIKETK----------MIQMQTTLDVADNTGARAVMCIKVLG-SKRR Y--AGIGDIIKVSVKDAAPR-G-------RVKKGEIYNAVVVRTAKGVRRKDGSLIRFGGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLIQ-L--NTLKPAEGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTPVRLSELIDVQALKAA-GVVGAK---------VIK--SGE-L-S-R-K-VVL- RGITATAGARAAIEAAGGSL-K---EQK--GRN---TGLA-SRGTHVSFG----------EFGLKAT--GRGRLTARQIE AARRAINRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--EG-- VSEELAREAFRLAAAKLPISTTF-VKKVSRLRRAVPTRRKI----AQLRVHRLSVFRSNLHIYANIISP---E--GDRVL VSASTL-EAEV-RAQLGGA-GKG-GNATAAALVGKRVAEK--AKAAG-IELVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-TTAIIRGVHISAQK TRLVADLIRGKSVAQALNILTFS---------------------------------PKKAAVILKKAVESAIAN----A- EHND-GADIDELKVTTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGAMNNIRKGDEVIVLTGR------DK-KRR GTVLARVDADH---VL--VEGVNVVKKHVK----AN--PMANNP-GGIVEKTMPIHVSNVA-LFNPAT-------GK--G --DRVGVQE----V--------DGKVR---VFRSNG---AVV--MGQKIHPTGFRLA--VT-RNWTSRWFA------DDK A--FGTMLAEDIRVREYL--KKKLK-----SASVGRVIIERPA-K-NARITVYSARPGVVIGKRGEDIENLKADLQRLVH VNIEEIRK---PETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLKANIDYGTSEAHTTYGVIGIKVWVYMSMSDPIADMLTRIRNAQQVDKTTVTM-PASKLKVAIATVLKDEGYIDGYS VKG----T---Q----AKPELEITLKYY----AG-------R---PVIERIERVSRPGLRIYKGRTSIPQVMNGLGVAIV STSRGVMTDRKARANGVGGEVLCYVAMKNQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAVVRGPVPLPTRIRRYDVLRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMRLDLPAGVDVEIALQRTLVGKVVSNKMDKTVVVLVERRVKHPIFG KIIMRSAKYKAHDES--NQYNEGDTVEIAEGRPISRSKAWRVVRLVEAA------------------------------- -MSRSI-KKGPFVDA-HLIKKVDAAVA---GKDKK----PIKTWSRRSTVLPEFIGLTIAVHNGRQHVPVYINE-NMVGH KLGEFALTRTFKGHA------A---DK----KSK-------R >BETA_Bordetella_parapertussis_12822 Concatenation of 2 sequences MALVKVKPTSAGRRGMVKVVSPK-LHKG------------AP-HAALLEKKTRGSGRNNNGHITVRH-RGGGHKQH---- YRVVDFR-R--NK-DGIPAKVERLEYDPNRTAHIALLCYA-DGERRYIIAPRGLEVGATLISGI-E-AP-IRAGNTLPIR NIPVGTTIHCIEMIPGKGAQMARSAGASAVLMAR--EGTYAQVRLRSGEVRRVHIQCRATIGEVGNEEHSLRQIGKAGAM -RWR-----GVR-P-TVRGVAMNPIDHPHGGGEGRT----GEAREPVSP---WGTPAKGFKTR-RNKR-TN-N-MIVQRR --------------------------------HRL---G-LVGRKVGMTRIFT-EDGE---------SIPVTVLDVSNNR VTQVK----SLE----S--DGY--AAIQVTY-------GT--RVVK----------PQAGHYK----------------- ---AG-AEAGSILKEFRL------DPARAAEF-----AA---GA-VIAV--ESV-FEAGQQVDVTGTSIGKGFAGTIKRH NFGS-QRASHGNSRSHRV-PGSIGQA-QDPG-RIFPGKRMSGHMGDVTRTVQNLDVVRVDAERG---------------- ----------LLMVKGA-VPGHAGGDVIVR--MDLKLLN-DQGQA--ATFSAPDTIF----GR-DF-NEALVHQIVVAFQ ANARSGNRAQKDRAE--------VK-HSTKKPW---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRAFPNS-PEENFSQKVNKKMYRAGIRSILSQLARED----------------R-VAVVDTF----TLE-S------ --PKTKLII--TDNVD--E---NVYLATRNLPHVA-V---------------VEPRYADPLSLIHYKK----VLITKPAI AQLESRLQEFYKSKV----VADLQAKFGYKCVMEVPRITKITLNMGVS-EAVADKKVIEHAVSDLTKISGQKPVVTKTRK AIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLTAFSFPFMSRIA-K--YPVELPKGVEAS-I--- -Q-P--D-QITVKGPLGTLVQSL--TG-D--VNVAQED-GK--LTF----V-V--ANDRHAN-AMSGTLRALVANMVTGV SKGFERKLNLVGVGY--RAQIQG-DA--VKLQ--LGFSHDVVHQL-P-A-GVKAECP--T-QTEIVIKG-PNKQVVGQVA AEIRKYR------EPEPY---KGKGVRYADERVVIKETK----------MIQMQTTLDVADNTGARAVMCIKVLG-SKRR Y--AGIGDIIKVSVKDAAPR-G-------RVKKGEIYNAVVVRTAKGVRRKDGSLIRFGGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLIQ-L--NTLKPAEGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTPVRPSELIDVQALKAA-GVVGAK---------VIK--SGE-L-S-R-K-VVL- RGITATAGARAAIEAAGGSL-K---EQK--GRN---TGLA-SRGTHVSFG----------EFGLKAT--GRGRLTARQIE AARRAINRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--EG-- VSEELAREAFRLAAAKLPISTTF-VKKVSRLRRAVPTRRKI----AQLRVHRLSVFRSNLHIYANIISP---E--GDRVL VSASTL-EAEV-RAQLGGA-GKG-GNATAAALVGKRVAEK--AKAAG-IELVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-TTAIIRGVHISAQK TRLVADLIRGKSVAQALNILTFS---------------------------------PKKAAVILKKAVESAIAN----A- EHND-GADIDELKVTTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGAMNNIRKGDEVIVLTGR------DK-KRR GTVLARVDADH---VL--VEGVNVVKKHVK----AN--PMANNP-GGIVEKTMPIHVSNVA-LFNPAT-------GK--G --DRVGVQE----V--------DGKVR---VFRSNG---AVV--MGQKIHPTGFRLA--VT-RNWTSRWFA------DDK A--FGTMLAEDIRVREYL--KKKLK-----SASVGRVIIERPA-K-NARITVYSARPGVVIGKRGEDIENLKADLQRLVH VNIEEIRK---PETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLKANIDYGTSEAHTTYGVIGIKVWVYMSMSDPIADMLTRIRNAQQVDKTTVTM-PASKLKVAIATVLKDEGYIDGYS VKG----T---Q----AKPELEITLKYY----AG-------R---PVIERIERVSRPGLRIYKGRTSIPQVMNGLGVAIV STSRGVMTDRKARANGVGGEVLCYVAMKNQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAVVRGPVPLPTRIRRYDVLRS PHVNKTSR-DQFEIHTHQRLMDIVDPTDKTVDALMRLDLPAGVDVEIALQRTLVGKVVSNKMDKTVVVLVERRVKHPIFG KIIMRSAKYKAHDES--NQYNEGDTVEIAEGRPISRSKAWRVVRLVEAA------------------------------- -MSRSI-KKGPFVDA-HLIKKVDAAVA---GKDKK----PIKTWSRRSTVLPEFIGLTIAVHNGRQHVPVYINE-NMVGH KLGEFALTRTFKGHA------A---DK----KSK------R- >BETA_Bordetella_pertussis_Tohama_I Concatenation of 2 sequences MALVKVKPTSAGRRGMVKVVSPK-LHKG------------AP-HAALLEKKTRGSGRNNNGHITVRH-RGGGHKQH---- YRVVDFR-R--NK-DGIPAKVERLEYDPNRTAHIALLCYA-DGERRYIIAPRGLEVGATLISGI-E-AP-IRAGNTLPIR NIPVGTTIHCIEMIPGKGAQMARSAGASAVLMAR--EGTYAQVRLRSGEVRRVHIQCRATIGEVGNEEHSLRQIGKAGAM -RWR-----GVR-P-TVRGVAMNPIDHPHGGGEGRT----GEAREPVSP---WGTPAKGFKTR-RNKR-TN-N-MIVQRR -----------------------------------------MGRKVGMTRIFT-EDGE---------SIPVTVLDVSNNR VTQVK----SLE----S--DGY--AAIQVTY-------GT--RVVK----------PQAGHYK----------------- ---AG-AEAGSILKEFRL------DPARAAEF-----AA---GA-VIAV--ESV-FEAGQQVDVTGTSIGKGFAGTIKRH NFGS-QRASHGNSRSHRV-PGSIGQA-QDPG-RIFPGKRMSGHMGDVTRTVQNLDVVRVDAERG---------------- ----------LLMVKGA-VPGHAGGDVIVR--MDLKLLN-DQGQA--ATFSAPDTIF----GR-DF-NEALVHQIVVAFQ ANARSGNRAQKDRAE--------VK-HSTKKPW---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRAFPNS-PEENFSQKVNKKMYRAGIRSILSQLARED----------------R-VAVVDTF----TLE-S------ --PKTKLII--TDNVD--E---NVYLATRNLPYVA-V---------------VEPRYADPLSLIHYKK----VLITKPAI AQLESRLQEFYKSKV----VADLQAKFGYKCVMEVPRITKITLNMGVS-EAVADKKVIEHAVSDLTKISGQKPVVTKTRK AIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLTAFSFPFMSRIA-K--YPVELPKGVEAS-I--- -Q-P--D-QITVKGPLGILVQSL--TG-D--VNVAQED-GK--LTF----V-V--ANDRHAN-AMSGTLRALVANMVTGV SKGFERKLNLVGVGY--RAQIQG-DA--VKLQ--LGFSHDVVHQL-P-A-GVKAECP--T-QTEIVIKG-PNKQVVGQVA AEIRKYR------EPEPY---KGKGVRYADERVVIKETK----------MIQMQTTLDVADNTGARAVMCIKVLG-SKRR Y--AGIGDIIKVSVKDAAPR-G-------RVKKGEIYNAVVVRTAKGVRRKDGSLIRFGGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLIQ-L--NTLKPAEGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTPVRLSELIDVQALKAA-GVVGAK---------VIK--SGE-L-S-R-K-VVL- RGITATAGARAAIEAAGGSL-K---EQK--GRN---TGLA-SRGTHVSFG----------EFGLKAT--GRGRLTARQIE AARRAINRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--EG-- VSEELAREAFRLAAAKLPISTTF-VKKVSRLRRAVPTRRKI----AQLRVHRLSVFRSNLHIYANIISP---E--GDRVL VSASTL-EAEV-RAQLGGA-GKG-GNATAAALVGKRVAEK--AKAAG-IELVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-TTAIIRGVHISAQK TRLVADLIRGKSVAQALNILTFS---------------------------------PKKAAVILKKAVESAIAN----A- EHND-GADIDELKVTTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGAMNNIRKGDEVIVLTGR------DK-KRR GTVLARVDADH---VL--VEGVNVVKKHVK----AN--PMANNP-GGIVEKTMPIHVSNVA-LFNPAT-------GK--G --DRVGVQE----V--------DGKVR---VFRSNG---AVV--MGQKIHPTGFRLA--VT-RNWTSRWFA------DDK A--FGTMLAEDIRVREYL--KKKLK-----SASVGRVIIERPA-K-NARITVYSARPGVVIGKRGEDIENLKADLQRLVH VNIEEIRK---PETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLKANIDYGTSEAHTTYGVIGIKVWVYMSMSDPIADMLTRIRNAQQVDKTTVTM-PASKLKVAIATVLKDEGYIDGYS VKG----T---Q----AKPELEITLKYY----AG-------R---PVIERIERVSRPGLRIYKGRTSIPQVMNGLGVAIV STSRGVMTDRKARANGVGGEVLCYVAMKNQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAVVRGPVPLPTRIRRYDVLRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMRLDLPAGVDVEIALQRTLVGKVVSNKMDKTVVVLVERRVKHPIFG KIIMRSAKYKAHDES--NQYNEGDTVEIAEGRPISRSKAWRVVRLVEAA------------------------------- -MSRSI-KKGPFVDA-HLIKKVDAAVA---GKDKK----PIKTWSRRSTVLPEFIGLTIAVHNGRQHVPIYINE-NMVGH KLGEFALTRTFKGHA------A---DK----KSK------R- >BETA_Bordetella_petrii Concatenation of 2 sequences MALVKVKPTSAGRRGMVKVVSPN-LHKG------------AP-HAALLEKKTRGSGRNNNGHITIRH-RGGGHKQH---- YRVVDFR-R--NK-DGIPAKVERLEYDPNRTAHIALLCYA-DGERRYIIAPRGLEVGATLVSGI-E-AP-IRAGNTLPIR NIPVGTTIHCIEMIPGKGAQMARSAGASAVLLAR--EGTYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRQIGKAGAM -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----GEAREPVSP---WGTPSKGFKTR-RNKR-TN-N-MIVQRR --------------------------------HRL---G-LVGRKVGMTRIFT-EEGE---------SIPVTVLDVSNNR VTQIK----SLE----A--DGY--AAVQVAY-------GT--RVAQ----------PQTGHYK----------------- ---AG-TEAGSILKEFRL------DPARLAEF-----TP---GA-VIAV--ESV-FEAGQQVDVTGTTIGKGFAGTIKRH HFGS-QRASHGNSRSHRV-PGSIGQA-QDPG-RIFPGKRMSGHLGDVTRTVQNLDVVRVDAERG---------------- ----------LLLVKGA-VPGHAGGDVVVR--MDLKLLN-DQGQA--ATFSAPDTIF----GR-DF-NEALVHQVVVAYQ ANARSGNRAQKDRAE--------VK-HTTKKPW---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRTFPNS-PEENFSQKVNKKMYRAGIRSILSQLARED----------------R-IAVVDTF----GLE-S------ --PKTKLII--TDAVD--E---NVYLATRNLPHVA-V---------------VEPRYADPLSLIHYKK----VLITKPAI AQLESRLQDFYKSKV----APDLQAKFGYKSTMEVPRITKVTLNMGVS-EAVADKKVIEHAVSDLTKIAGQKPVVTKTRK AIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLTAFSFPFMSRIA-K--YPVELPKGVEAN-I--- -Q-Q--D-QITVKGPLGTLSQAL--TG-D--VTVALDN-GK--LTF----V-A--ANERHAG-AMSGTVRALVANMVTGV SKGFERKLTLVGVGY--RAQVQG-DA--VKLQ--LGFSHDIVHKL-P-A-GVKAECP--T-QTEIVIKG-SNKQVVGQVA AELRAYR------EPEPY---KGKGVRYADERVVIKETK----------MIQMQTTLDVADNTGARAVMCIKVLG-SKRR Y--AGIGDIIKVSVKDAAPR-G-------RVKKGEIYNAVVVRTAKGVRRKDGSLIRFGGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLIQ-L--NTLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTPVRLSDLIDVQTLKAA-GVVGAK---------VIK--SGE-L-S-R-K-VTL- KGLTATAGARAAIEAAGGSL-K---EQK--GRN---TGLA-TRGTHVSFG----------EFGLKAT--GRGRLTARQIE AARRAINRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--EG-- VSEELAREAFRLAAAKLPISTTF-VKKVSRLRRAVPTRRKI----SELRVHRLSIFRSNLHIYANIISP---E--GDRVL VSASTL-EPEV-RAQLAGQSGQG-GNTAAATLVGKRVAEK--AKAAG-IELVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-TTAIIRGVHISAQK TRLVADLIRGKSVAQALNILTFS---------------------------------PKKAAGILKKAVESAIAN----A- EHND-GADIDELKITTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGAMNNIRKGDEVIVLTGR------DK-KRR GTVLARVDAD---HVL--VEGVNVVKKHVK----AN--PMANNP-GGIVEKTLPIHISNVA-LFNPAT-------GK--G --DRVGVKE----V--------DGKVR---VFRSNG---AVV--MGQKIHPTGFRLA--VT-RNWSSRWFA------DDK A--FGSMLAEDIRVREYL--KKKLK-----SASVGRVIIERPA-K-NARITVYSARPGVVIGKRGEDIESLKADLQRLVH VNIEEIRK---PETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLKANIDYGTSEAHTTYGVIGIKVWVYMSMSDPIADMLTRIRNAQQVDKVTVSM-PSSKLKAAIAAVLQDEGYIDGFE VKG----T---Q----AKPELEITLKYY----AG-------R---PVIERIERVSRPGLRIYKGRSNIPQVMNGLGVAIV STSRGVMTDRKARANGVGGEVLCYVAMKNQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAVVRGPVPLPTRIRRYDVLRS PHVNKSSR-DQFEIRTHQRLMDIVDPTDKTVDALMRLDLPAGVDVEIALQRTLVGKVVSNKMDKTVVVLVERRVKHPIYG KIVMRSAKYKAHDES--NQYNEGDTVEIAEGRPISRSKSWNVVRLVEAV------------------------------- -MSRSI-KKGPFVDA-HLIKKVDTAVA---GKDKK----PIKTWSRRSTILPEFIGLTIAVHNGRQHVPVYINE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK------R- >BETA_Burkholderia_ambifaria_MC40-6 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKN-LHQG------------KP-FAALLDSQSSTAGRNNNGRITTRH-KGGGHKQH---- YRIVDFR-RT--K-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGR-DPVSP---WGTPAKGYRTR-SNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-VVGA--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----ILE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-I---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAIADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAI--NP-L--VNVANND-GT--LNL----S-P--VDEREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYSDEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--AGIGDIIKVTVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------DFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVVTGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEQLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYG KYVVRSKKYHAHDEA--NTCNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_cenocepacia_AU_1054 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKN-LHQG------------KP-FAALLDSQSSTAGRNNNGRITTRH-KGGGHKQH---- YRIVDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPAKGYRTR-SNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-VVGA--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----ILE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-I---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAIADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAI--NP-L--VNVANND-GT--LNL----S-P--VDEREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETKASGLSWERQTMIQTESRLEVADNTGAREVLCIKVLG-SKRR Y--AGIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLSDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVVTGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEQLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK------K- >BETA_Burkholderia_cenocepacia_J2315 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKN-LHQG------------KP-FAALLDSQSSTAGRNNNGRITTRH-KGGGHKQH---- YRIVDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPAKGYRTR-SNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-VVGA--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQVVIAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----ILE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-I---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAIADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAI--NP-L--VNVANND-GT--LNL----S-P--VDEREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETK----------MIQTESRLEVADNTGAREVLCIKVLG-SKRR Y--AGIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVVTGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEQLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_cepacia_AMMD Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKN-LHQG------------KP-FAALLDSQSSTAGRNNNGRITTRH-KGGGHKQH---- YRIVDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPAKGYRTR-SNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-VVGA--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----ILE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-I---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAIADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAI--NP-L--VNVANND-GT--LNL----S-P--VDEREAN-ALSGTMRAIIANAVQGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYSDEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--AGIGDIIKVTVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------DFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVVTGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEQLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYG KYVVRSKKYHAHDEA--NTCNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_glumae_BGR1 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-FAALLDTQSSTAGRNNNGHITTRH-KGGGHKQH---- YRIVDFR-R--NK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVVVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCVEMLPGKGAQIARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGKT----AAGRDPVSP---WGTPAKGFRTR-SNKRTTT---MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-ADGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DATKAAEL-----SN---GA-IVGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGTKGGKVFVT--MELKLLN-ANGQEG-AVVNASDVVF----GR-DY-NEALIHQIVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDL----TLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLPNVA-V---------------VEPRYADPLSLIYFKK----ILVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSIMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVT-L--- -A-N--G-SITVKGPLGTISQVV--NP-L--VTVANDN-GT--LNL----A-P--VDEREAN-ALSGTMRAIIANMVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEILIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKSARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EYGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNSHIYAQVFSP---C--GTKVV ASASTL-EAEV-RAQLADQSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEIIVITGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKAMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKT----E---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQKQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIENRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPLSKTKAWTVSRLIEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_mallei_ATCC_23344 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-HAALLDTQSSKAGRNNNGRITTRH-QGGGHKQH---- YRVIDFR-RT--K-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGLYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-A--AGR-DPVSP---WGTPTKGFRTR-RNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------EADKAAEL-----SN---GA-VIGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFGS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-SNGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----VLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLPHVA-V---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISIMTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAV--NP-L--VNVANND-GT--LNL----S-P--VDDREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GIKAETP--T-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------DGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVSM-PSSKVKVAIAQVLKDEGYIDDFA VKA----D---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWAVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_mallei_NCTC_10229 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-HAALLDTQSSKAGRNNNGCITTRH-QGGGHKQH---- YRVIDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGLYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-A--AGRD-PVSP---WGTPTKGFRTR-RNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------EADKAAEL-----SN---GA-VIGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFGS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-SNGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----VLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLPHVA-V---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAV--NP-L--VNVANND-GT--LNL----S-P--VDDREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GIKAETP--T-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------DGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVSM-PSSKVKVAIAQVLKDEGYIDDFA VKA----D---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWAVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_multivorans_ATCC_17616 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-HAALLDTQSSKAGRNNNGRITTRH-QGGGHKHH---- YRVIDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-A--AGRD-PVSP---WGTPTKGFRTR-RNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVVDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-IVGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFGS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQIVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----VLE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-V---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARLQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRLVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-VITVKGPLGTITQAV--NP-L--VKVANND-GT--LNL----A-P--ADEREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKSARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPIQTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVIAGK------DK-GKR GVVLAVAAD----RVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-VVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKT----E---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGRVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWAVARLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_phymatum_STM815 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-YAPLLDTQSSTAGRNNNGHITTRH-KGGGHKHH---- YRIVDFR-RT--K-DGIPAKVERLEYDPNRSANIALVVYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGTYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGR-DPVSP---WGTPTKGYRTR-SNKR-TT-S-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GT--RVTK----------PLAGHLK----------------- ---AG-VQAGEILKEFQI------DAAKAAEL-----SS---GA-VIGV--D-L-FEVGQKVDVQGTSIGKGYAGTIKRY NFSS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-ANGQEG-AAVNASDVVF----GR-DY-NEALIHQIVVAYQ ANARSGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-IAVVDEL----TLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLAHVA-V---------------VEPRYADPLSLIYFKK----VLITKAAV AQIEARLQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVITKARK AIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVA-L--- -S-D--E-RITVKGPLGSISQNA--NR-L--VKVVNDN-GT--LKF----E-P--ADEREAN-AMSGTMRALVANMVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--S-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYANEVVILKETK----------MIQTETRLEVADNTGAREVMCIKVLG-SKRR Y--ANIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-TKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLIGAK---------IIA--TGE-L-K-R-K-IVV- KGLSATKGARAAIEAAGGSF-K---EQK--GRN---TGVA-TRGNAVSFG----------EYGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPLKTTF-MKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLAVGEN----RVT--VEGLNIAKKHVK----PN--PMKGTT-GGVEAKAMPLNISNVA-LVD-AN-------GK--P --SRVGIKV----E--------GDKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKSELQKRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVTM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPLSKTKAWTVSRLVEAA------------------------------- -MARSI-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVTE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK------K- >BETA_Burkholderia_phytofirmans_PsJN Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKE-LHKG------------KP-YAPLLDSQSSTAGRNNNGHITTRH-KGGGHKHH---- YRVVDFR-R--NK-DGIAAKVERLEYDPNRSANIALVLYA-DGERKYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGIYAQVRLRSGEIRRVHVECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT----AAGRDPVSP---WGTPAKGYRTR-SNKRTTS---MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GT--RVTK----------PLAGHLK----------------- ---AG-VQAGEILKEFQI------DAAKAAEL-----SN---GT-VVGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFAS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDDTVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-ANGQEG-AGVSASDVVF----GR-DY-NEALIHQVVVAYQ ANARSGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-ISVVDEL----TLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLAHVA-V---------------VEPRYADPLSLIYFKK----ILITKAAV AQIEARLQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVITKARK AIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPVAL-QGAEVA-L--- -S-D--D-RITVKGPLGTITQAA--NR-L--VKVVNDN-GT--LNF----E-P--VDEREAN-AMSGTMRALVANMVNGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYANEVVILKETK----------MIQTETRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVTVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLSDLIDLLALKQA-GLIGAK---------IIK--TGE-L-K-R-K-VVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISHKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADQTGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALADAAREAGLK F-------------------------------------------------------------MME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKITSIYIDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLSVGEG----KVI--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLQISNVA-LVD-AN-------GK--A --SRVGIKV----E--------GDKVR---FLKTTG---AEL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKSELQKRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVTM-PSSKVKVAIAQVLKDEGYIDDFA VKS----E---G----AKSELNIVLKYY----AG-------R---PVIERIERVSKPGLRVYRGRNDIPVVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDDA--NTYNEGDLVEIQETRPISKTKAWVVARLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_pseudomallei_1710b Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-HAALLDTQSSKAGRNNNGRITTRH-QGGGHKQH---- YRVIDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGLYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-A--AGRD-PVSP---WGTPTKGFRTR-RNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------EADKAAEL-----SN---GA-VIGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFGS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-SNGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----VLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLPHVA-V---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAV--NP-L--VNVANND-GT--LNL----S-P--VDDREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GIKAETP--T-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETKVSGLSWERQTMIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------DGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVSM-PSSKVKVAIAQVLKDEGYIDDFA VKA----D---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWAVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_pseudomallei_668 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-HAALLDTQSSKAGRNNNGRITTRH-QGGGHKQH---- YRVIDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGLYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-A--AGRD-PVSP---WGTPTKGFRTR-RNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------EADKAAEL-----SN---GA-VIGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFGS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-SNGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----VLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLPHVA-V---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAV--NP-L--VNVANND-GT--LNL----S-P--VDDREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GIKAETP--T-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------DGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVSM-PSSKVKVAIAQVLKDEGYIDDFA VKA----D---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWAVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_sp_383 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKN-LHQG------------KP-FAALLDSQSSTAGRNNNGRITTRH-KGGGHKQH---- YRIVDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPAKGYRTR-SNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-VVGV--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----ILE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-I---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAIADKKIIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQAI--NP-L--VNVANND-GT--LNL----A-P--VDEREAN-ALSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYSDEVVILKETK----------MIQTESRLEVADNTGAREVLCIKVLG-SKRR Y--AGIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLSDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVVTGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEQLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNGQMVEKVSVSM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERIERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_thailandensis_E264 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-HAALLDTQNSKAGRNNNGRITTRH-QGGGHKHH---- YRVIDFR-RT--K-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-A--AGR-DPVSP---WGTPTKGFRTR-RNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VQTGEILKEFRI------EADKAAEL-----SN---GA-VIGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFGS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDETVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-SNGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----VLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLPHVA-V---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKVIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-SITVKGPLGTITQAV--NP-L--VNVANND-GT--LNL----S-P--VDDREAN-ALSGTMRAIIANMVQGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GIKAETP--T-QTEIVIKG-IDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADEVVILKETKVSGLSWERQTMIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVSVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLVDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADKSGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------DGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVIIERPA-K-NARITIFSSRPGVVIGKKGEDIELLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGVIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVSM-PSSKVKVAIAQVLKDEGYIDDFA VKA----D---G----AKAELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNEIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDEA--NTYNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_vietnamiensis_G4 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHQG------------KP-HAALLDTQSSTAGRNNNGRITTRH-KGGGHKHH---- YRIVDFR-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPTKGYRTR-SNKR-TT-T-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEILKEFRI------DAAKAAEL-----SN---GA-VVGA--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFSS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTVTVQNLEIARIDAERK---------------- ----------LLLVKGA-IPGAKGGKVFVT--MELKLLN-ENGQEG-AVVNASDVVF----GR-DY-NEALIHQVVVAYQ ANARQGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-LSVVEDI----ILE-A------ --PKTKLII--TDTVD--E---NLYLASRNLPHVA-I---------------VEPRYADPLSLIYFKK----VLVTKAAV AQIEARFQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAIADKKVIENAVGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPIAL-QGAEVK-L--- -A-D--G-AITVKGPLGTITQPV--NP-L--VNVANND-GT--LNL----A-P--VNEREAN-AMSGTMRAIIANAVHGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYSDEVVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--AGIGDIIKVTVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLGDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-IVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTAF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAELADKSGKG-GNVNAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVVTGK------DK-GKR GVVLAVGAE----HVT--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLHISNVA-LVD-AN-------GK--A --SRVGIKV----E--------EGKVR---FLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEQLKTELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVAM-PSSKVKVAIAQVLKDEGYIDDFA VKA----E---G----AKSELNIALKYY----AG-------R---PVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYG KYVVRSKKYHAHDEA--NTCNEGDLVEIQETRPVSKTKAWTVSRLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Burkholderia_xenovorans_LB400 Concatenation of 2 sequences MAIVKVKPTSPGRRAMVKVVNKD-LHKG------------KP-FAPLLDSQSTTAGRNNNGHITTRH-KGGGHKHH---- YRVVDFR-R--NK-DGIAAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVTVGQQLMSGS-E-AP-IRAGNTLPIR NIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAR--EGIYAQVRLRSGEIRRVHVECRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPTKGYRTR-SNKR-TT-S-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-AEGD---------SIPVTVLDVSDNR VTQIK----TVE----T--DGY--TAVQVAF-------GT--RVTK----------PLAGHLK----------------- ---AG-VQAGEILKEFQI------DAAKAAEL-----SN---GT-VVGP--D-L-FEVGQKVDVQGVSIGKGYAGTIKRY NFAS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDDTVTVQNLEIARIDADRK---------------- ----------LLLVKGA-VPGAKGGKVFVT--MELKLLN-ANGQEG-AGVSASDVVF----GR-DY-NEALIHQVVVAYQ ANARSGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMHRAGLCSIFSQLAREG----------------R-ISVVDEL----TLE-A------ --PKTKLVI--TDTVD--E---NLYLASRNLAHVA-V---------------VEPRYADPLSLIYFKK----ILITKAAV AQIEARLQEFYKEKV----VPGLIEKFGYKSVMEVPRITKITLNMGLG-EAVADKKIIENAVGDLTKIAGQKPVITKARK AIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEID-----YDKI DALRGLNISITTT-----------------------AKTDDEAKALLASFKFPFMSRVG-K--SPVAL-QGAEVA-L--- -S-D--E-RITVKGPLGTISQAA--NS-L--VKVVNDN-GT--LKF----E-P--VDEREAN-AMSGTMRALVANMVNGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GIKAETP--T-QTEIVIKG-INKQQVGQVA AEVRGYR------PPEPY---KGKGVRYANEVVILKETK----------MIQTETRLEVADNTGAREVMCIKVLG-SKRR Y--ASIGDIIKVTVKEATPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-SERFMKIVSLAPEVLME-L--NNLKPAEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTSVRLSDLIDLLALKQA-GLVGAK---------IIA--TGE-L-K-R-K-VVV- KGLGATKGARAAIEAAGGSF-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISHKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VTEELAREAFRLAAAKLPLKTTF-IKTQSRLRRARQTRIKI----AELQVARLAVHRTNTHIYAQVFSP---C--GTKVL ASASTL-EAEV-RAQLADQTGKG-GNVAAATLIGKRIAEK--AKAAG-IESVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPVDKALNVLTFS---------------------------------PKKAAGIVKKVVLSAIAN----A- EHNE-GADIDELKITSIYIDKAASLKRFTARAKGRGNRIEKQSCHITVTVGNMNKIRKGDEVIVITGK------DK-GKR GVVLSVGEG----KVI--VEGINLVKKHVK----PN--PMKGTT-GGVEAKTMPLQISNVA-LVD-AN-------GK--A --SRVGIKV----E--------GDKIR---FLKTTG---AEL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNN N--FAAMLQEDIGVREYL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIELLKSELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYATSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKVSVTM-PSSKVKVAIAQVLKDEGYIDDFA VKS----E---G----AKSELNIVLKYY----AG-------R---PVIERIERVSKPGLRVYRGRNDIPVVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYG KYVVRSKKYHAHDDA--NTYNEGDLVEIQETRPISKTKAWVVARLVEAA------------------------------- -MARSV-KKGPFCDA-HLLKKVEAAAA---SRDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Chromobacterium_violaceum_ATCC_12472 Concatenation of 2 sequences MPIVKVKPTSAGRRAVVKVVNPD-LHKG------------AP-HAALVEKKNSTGGRNHNGHITTRH-RGGGHKKH---- YRLIDFR-RN--K-DGIPAKVERIEYDPNRTAHIALLCYA-DGERRYIIAPRGVKVGAVLLSGS-E-AP-IKAGNALPIR NIPVGTTIHCVEMQPGKGAQMVRSAGASAMLLAR--EGVYAQLRLRSGEIRLVHVDCRATVGEVGNEEHSLRKLGKAGAT -RWR-----GIR-P-TVRGTAMNPIDHPHGGGEGRT-G--EGR-VPVSP---WGTPAKGFRTR-RNKR-TD-N-MIVRRR --------------------------------MSL---G-LVGRKVGMTRIFA-EDGA---------TIPVTVLDMSSNR VTQIK----TAE----T--DGY--NAVQVTY-------GS--KVNK----------ADAGHFK----------------- ---AG-VEAGLGLAEFAL------SADALSNF-----KP---GD-AIAV--E-I-FTVGQLVDVTGTSKGKGFSGVIKRH NFSS-NRASHGNSRSHNT-PGSIGQA-QDPG-RVFPGKRMAGQYGNVKSTVQCLEIVRVDAERQ---------------- ----------LILVKGA-VPGAKNGDVVVR--MELNVIN-TQGKAV-GSLQVSDALF----GR-EY-NEALVHQVVTAFL ANARSGNRAQLTRAE--------VK-HSTKKPF---------RQKGTGNAR--------AGM---TS-TP----NR---- RGGGRAFPNK-PDENFTQKVNRKMYRAGIATILSQLVRDE----------------R-LIVVDDL----SVA-S------ --PKTKLFI--TNELS--E---NLYLSSRNLPNML-V---------------IEAVQADPYSLLRFKK----TVITRDAV KQLEARLYDFYKDSV----VPELMKQFGYKSIMQVPRIEKITVNMGVG-EAVADKKVMEFAVGDLEKIAGQKPVVTTARK SIAGFKIRDDYPVGCKVTLRRERMYEFLDRLVTIALPRVRDFRGVSA-KSFDGRGNYNMGVKEQIIFPEIE-----YDKI DALRGMNITITTS-----------------------AKTDEEARALLAAFKFPFMSRVA-K--NPVAIPAGVEVK-F--- -G-A--A-DVTVKGALGSLSTAL--CN-D--VEVKLDN-GQ--LTF----A-A--KNDKFAR-AMSGTLRALLNNMVNGV SKGFEKKLQLVGVGY--RAQAQG-DT--LNLS--LGFSHPVAHKM-P-A-GIKVETP--T-QTEILVKG-ADKQLVGQVA AEIRAYR------SPEPY---KGKGVRYADEVVVLKETK----------MIQMQTMLEVADNTGARHVQCIKVLG-SKRR Y--ASVGDIIKVSIKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGSLIKFDSNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLML-L--NTVQPGVGA-KHAKRRVG-RGIGSGL-GKTCGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVRLSELIDLLALKQA-GLVAAK---------VVL--SGK-V-E-R-A-VKL- RGISVTAGARAAIEAAGGSI-K---QHK--GRN---TGIA-TRGNKVSFG----------DFGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPITSKPAEVRMGGGK---------GSPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPIATVF-VKKQTRLRRARKTRARI----AELKMVRLSVHRTNSHIYAQIIDE---T--GNKVL ASASSL-EADV-RSAM----ANG-GNVAAAAVIGKRIAEK--AKAAG-IEQVAFDRSGFKYH--GRMKALADAAREHGLV F--------------------------------------------------------------MR-VSANLKSVRLSAQK CRLVADLVRGKSVDQALNILAFS---------------------------------PKKGAVIIKKVLESAIAN----A- EHNE-GADIDTLRVTSIFVDKGASLKRFTARAKGRGNRIEKQTCHISLTVGNMRKIRKGDEVVVITGK------DK-GKR GTVLRVLET----KLV--VEGVNVAKKHQK----PN--PVRGVA-GGIVEKTMPIDASNVA-IFNPAS-------QK--A --DRVGFKV---LE--------DGKVR---VFKSSG---EVI--MGQKIHPTGFRLA--VN-KNWSSKWFA------SSQ N--FPEMLKQDIEVREFL--KKRLG-----HASVGRVTIERPA-K-SARITIHSARPGVVIGKKGEDIEVLKQELQKRVH VNIEEVRK---PELDAQIIADGIASQLEKRVMFRRAMKRAMQNAMRL-GAEGIKIMSSGRLNGIDIARSEWYREGRVPL- -HTLRADVDYATSEAKTTYGIIGIKVWVYMSMHDPISDMLTRIRNGQHASKVKVSM-PSSKLKIALAQVLKEEGYIEDFA IAG----E---E----KKPVLDIQLKYY----AG-------R---PVIERIERVSRPGLRVYKGSTEIPKVMNGLGVAIL STSKGVMTDRKARAAGIGGELLCVVAMSSQKIRIRLKAFDYNLIDRSAQEIVETAKRTGAVVKGPVPLPTKIERFNVLRS PHVNKTSR-DQLEIRTHLRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLVRTLTGVVVSDKMDKTVTVLVERKVKHPIYG KIIRRSKKFHAHDEN--NEFKAGDLVVISESRPLSKTKSWVVTGLVEKS------------------------------- -MARSQ-KKGPFVDL-HLLKKVDAVRA---TSDKR----PIKTWSRRSTILPDFIGLTIAVHNGRTHVPVYVSE-NMVGH KLGEFSLTRTFKGHA------A---DK----KAK------KK >BETA_Dechloromonas_aromatica_RCB Concatenation of 2 sequences MALVKVKPTSPGRRGVVQVVNAS-LHKG------------KP-FAALVEAKSGNAGRNNNGRITVRH-QGGGHKQA---- YRVIDFK-RN--K-DGIPAKVERLEYDPNRTANIALLCYA-DGERRYIIANKGMVVGQPIMSGS-E-AP-IKSGNALPIR NIPVGTTICCVEMLPGKGAQLARSAGTSVQLLAR--EGTYAQIRLRSGEVRRVHVECRATIGEVGNEEHNLRKIGKAGAM -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRT-G--EGR-VPVNP---WGQPTKGYRTR-SNKR-TN-S-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFA-EDGA---------SIPVTVLDVSNNR VTQVK----TPE----I--DGY--AAIQVAF-------GK--RVSK----------PLAGHLK----------------- ---AG-VEAGHVLKEFQI------EADQLASF-----KA---GD-QVAV--T-I-FAEGQKVDVTGTSIGKGFQGGIKRH NFSS-NRASHGNSLSHNA-PGSIGMA-QDPG-RVFPGKRMAGHLGDVQSTMQGLTIVRVDADRQ---------------- ----------LLLVKGA-VPGAKGSDVVVR--MELKVIN-EQGQEA-AKLQASDVLF----GR-DF-NEALVHQIVVAYQ ANARSGDRQQKDRSE--------VR-HTTTKPW---------RQKGTGRAR--------AGS---NG-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMFRAGMAAILSELARQD----------------R-LVVIDDL----SVD-A------ --PKTKLVI--TDELN--E---NLYLSSRNLPNVL-V---------------LEAQEADPVSLVRFAK----VLVTKNAV AKFEARLQQFYKETI----VSDLVKQFGYKSVMEVPRITKITLNMGVG-EAVADKKVLENAVGDMQKIAGQKPVTTKARK SIAGFKIRDGYPIGCMVTLRGPRMFEFLDRLVTIALPRVRDFRGISG-KGFDGQGNYNMGVKEQIIFPEIE-----YDKI DALRGMNISITTT-----------------------AKTDAEAKALLVAFKFPFMSRIG-K--NPVVLPAGVEVT-V--- -G----E-QIVVKGPLGSLKTAA--HS-A--VNVAVEG-QN--VTV----S-K--VAGANAA-AMWGTMRANLNNMVTGV SKGFERKLQLVGVGY--RAQAQG-DT--LNLS--LGFSHPVAHKM-P-A-GVKVECP--T-QTEILIKG-SDKQQVGQVA AEIRAYR------KPEPY---KGKGVRYADEVVVIKETK----------MIQMQTTLDVADNTGARSVMCIKVLG-SRRR Y--AGIGDIIKVSIKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGSLVRFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMR-L--NTIKPGEGS-KKTAKRVG-RGIGSGL-GKTCGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FNSVRLTDLIDLLALQVA-GIVPAK---------VIL--SGA-I-S-R-K-VVL- KGVGATKGAKAAIEAVGGSI-K---EHK--GRN---EGLA-TRGTKVSFG----------EWGLKAI--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--DG-- VNEALAREAFALAAAKLPIPTTF-VKKQARLRRARKTRAKI----AELKAVRLCVNRTNCHIYAQIISP---C--GGKVL ASASTL-DTDV-RKDL----ANG-GNKAAATTIGKLIAER--AKAAG-IEQVAFDRSGLQYH--GRIQALAEAAREGGLK F--------------------------------------------------------------ME-TRASLRGVRLSAQK GRLVADLVRGKPVGQALNILAFC---------------------------------PKKGAGIVKKVLESAIAN----A- EHND-GADIDELTVKTIYVEKGMVLKRFTARAKGRGNRIIKPTCHIYLTVGNMEKIRKGDEIVVITGK------DK-GKR GTVLRRVDDEH---VL--VEGVNRAKKHVK----PN--PVKGVA-GGIVDKDMPIHISNVA-LFNPAT-------KK--A --DRVGFKA---LD--------DGKVR---VFKSNG---ELV--MGQKIHPTGFRLA--VT-KNWSSRWYA------NSK D--FPGMLNEDIKVREYL--KRKLA-----HASVGRVLIERPA-K-NARVTVYSARPGVVIGKKGEDIEQLRTDLQRIVH VSIEEIRK---PEIDAQLIADSIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKVMSAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYATSEALTTYGIIGIKVWVYMAMSDPIADMLTRIRNAQLAEKASVSM-PSSKVKVAIAAVLKDEGYVEDFA VRQ----A---D----GKANLEIALKYY----AG-------R---PVIERIERISKPGLRIYKGCDDIPRVMNGLGVAIV STPKGVMTDRKARASKVGGEVLCIVAMANQKIRIRLKAFDYRLIDQSAQEIVETAKRTGAVVRGPVPLPTRKQRFDILRS PHVNKASR-DQLEIRTHLRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGRVVSDKMDKTVTVLVERKVKHPMYG KVMVRSKKYHAHNEG--NSAKAGDLVEIVETRPVSRTKTWAVTSVLEKA------------------------------- -MGRSL-KKGPFVDA-HLIDKVEAVRA---TSDKR----PIKTWSRRSTILPEFIGLTIAVHNGKQHIPVFVTE-NMVGH KLGEFSLTRTFKGHT------A---GK----KAK------K- >BETA_Delftia_acidovorans_SPH-1 Concatenation of 2 sequences MAVIKLKPTTPGQRGTVKVTRDH-LHKG------------AG-FAPLLEPQHQKSGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RT--K-DGIPAKVERIEYDPNRTAHIALVCYA-DGERRYIIAPRNLEVGATIVSGS-E-AP-IRVGNTLPIR NIPVGSTIHCIELKIGAGAQIARSAGTSATLLAR--EGIYAQVRMRSGEVRKVHIECRATIGEVANEEHSLRRLGKAGVK -RWM-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-G--EGR-HAVDP---WGNLTKGYRTR-NNKR-TQ-S-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------AVPVTVVDVSNNR VTQVK----TQE----N--DGY--VALQVTF-------GS--RVTK----------PEAGHLK----------------- ---AG-VEAGEVMGEFRV------TEETAGKY-----AA---GS-VLPV-AE-L-FSVGQKVDVQGTSIGKGFAGTIKRH NFRS-QRASHGNSRSHNV-PGSISMA-QDPG-RVFPGKKMTGHMGDETITTQNLDVVRIDEARQ---------------- ----------LLLIKGA-VPGSKGGFVTVR--MQLELLN-EQGQAA-SKFDAPETVF----GR-EF-NEDLVHQIVIAYR ANARQGTRAQKDREQ--------VR-HTTAKPF---------KQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNL-PEENFTQKINKKMYRAGMVAILSQLAREG----------------R-LAVVDSL----KLE-S------ --PKTKMVI--AEEVD--E---NLYLASRNLKNVF-V---------------VEPRYADPVSLVHYKK----VLVTKGAI DKLKARLQKLYREKI----AAELKEKFGYTSSMEVPRLTKITLNMGVS-EAVADKKVMDNAVADLTKIAGQKPVVTKAKK AIAGFKIREGQAIGCMVTLRGVQMYEFLDRFVTVALPRVRDFRGISG-RSFDGRGNYNVGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------ARTDDECKALLAAFRFPFMSRVA-K--TPVAIPAGVDVS-I--- -K-D--D-QINVKGTGGALSQAQ--NA-L--VKISNNE-GK--LSF----E-P-VNDSREAN-AMSGTMRQLVNNMVVGV SKGFEKKLSLVGVGF--KASASG-SK--LNLA--IGFSHPVNFEM-P-A-GITVTTP--T-PTEILVKG-ADRQAVGQMA AEIRAVR------PPEPY---KGKGIRYSDEKVVIKETK----------MIQTESRLEVADNTGAKSVQCIKVLG-SHRR Y--ASVGDIIKVTIKEAAPR-G-------RVKKGEVYSAVVVRTAKGIRRADGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-NEKFMKIVSLAPEVLME-L--NSIKPAEGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVTLSALVDLAALKQA-GLVGVK---------IIK--SGE-I-S-K-A-VKL- NGIGATAGAKAAIEAAGGSI-K---EQK--GRN---TGIA-TRGNSVAFG----------DFGLKST--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISTKPAEVRMGNGK---------GNPEYYVAEIQP-GKVLYEI--VG-- VPEELAREAFRLAAAKLPLRTTF-VKKEQRLRRARQTRIRI----AQQGVARLSVNRTNLHIYASVVSE---D--GTKVL ASASTA-EAEV-RTQL-GAIGKG-GNVAAATLIGKRIAEK--AKAAG-VEKVAFDRAGFAYH--GRVKALAEAAREAGLQ F-------------------------------------------------------------MSE-TRAVLRGVRLSVDK GRLVADLIRGKKVDQALNILTFT---------------------------------QKKAAVIIKKVLESAIAN----A- EHND-GADIDELKVKTIFVEQGTTLKRFTARAKGRGNRISKPTCHVYVTVGNMNKIRKGDQIIVLTGR------DK-GKQ GVVSARKDDSH---LL--IDGINMVKKHVK----PN--PMKGTT-GGIVEKAMPIHQSNVA-IFNAAT-------GK--A --DRVGIKV---QA--------DGRVR---VFKSSG---AEI--MGQKIHPTGFRLA--VS-RNWASRWYA------SNR D--FAGMLAEDIKVREFL--KAKLK-----NAAVSRILIERPA-K-NARITIFSARPGVVIGKKGEDIENLKKELATRVA VNIEEVRK---PEIDAKLIADSICQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARCEWYREGRVPL- -HTLRADIDYGFSEAKTTYGVIGVKVWVYMSMSDPIADLLTRIRNAQMVSKTTVTA-PSSKVKVAIAQVLKDEGYIDGFQ VKT----D---A----GKSELEITLKYY----AG-------R---PVIERIERVSRPGLRVYKGRDAIPQVMNGMGVAIV TTPKGVMTDRKARATGVGGEVLCYVAMSKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGKVVSDKRAKTVTVMVERRVKHPIYD KIMIKSSKYHAHDEQ--GEYKLGDVVEITESRPLSKTKNWVATRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLLAKAEKAVA---TKDKK----PVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYVTD-QMVGH KLGEFALTRTFKGHP------A---DK----KAK-------K >BETA_Diaphorobacter_sp_TPSY Concatenation of 2 sequences MAVIKIKPTSPGQRGTVKISRDH-LYKG------------EA-FAGLLEPQFQKAGRNNNGHITTRH-KGGGHKHH---- YRVVDFR-R--NK-DAIPAKVERIEYDPNRTAHIALVCYA-DGERRYIIAPRNLEVGATIVSGS-E-AP-IRVGNTLPIR NIPVGSTIHCIELKPGAGAQIARSAGTSATLLAR--EGVYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRQLGKAGVK -RWM-----GIR-P-TVRGVAMNPIDHPHGGGEGRT-G--EGRH-AVDP---WGNLTKGYRTR-NNKR-TQ-V-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------AVPVTVVDVSNNR VTQVK----TQE----N--DGY--VSLQVTF-------GS--RVTK----------PEAGHLK----------------- ---AG-VEAGEIIREFRV------TPEVAGKY-----AA---GA-AVPV-AD-V-FAVGQKVDVQGTSIGKGFAGTIKRH NFGS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKKMTGHLGDVTVTTQNLDVVRIDEARQ---------------- ----------LLLIKGA-VPGSKGGFVTVR--MQLELLN-EQGQAA-SKVDVPETVF----DR-QY-NEDLIHQIVVAYQ ANARQGTRAQKDREQ--------VK-HSTKKPF---------KQKGTGNAR--------AGM---TS-SP----LW---- RGGGRIFPNL-PEENFSQKINKKMYRAGMASILSQLAREG----------------R-LAVVDSL----KLD-T------ --PKTKMVI--ADEVD--E---NLYLASRNLKNVF-V---------------TEPRYADPVSLVHYKK----VLVTKGAI DKLKARLQEIYRDKI----APELVKQFGYTSPMQVPRLTKITLNMGVS-EAVADKKIMDNAVADLTKIAGQKPVVTKAKK AIAGFKIREGQAIGCMVTLRGAQMYEFLDRFVTIALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKTDEEAKALLTAFRFPFMSRVG-K--SPVSIPAGVDVS-I--- -K-D--D-QISVKGAGGVLSLAQ--NA-L--VKVSNNE-GK--LSF----E-P-VNDSREAN-AMSGTVRQLVNNMVVGV SKGFEKKLTLIGVGF--KAAASG-NK--LNLA--IGFSHPVNFEM-P-T-GITVATP--T-PTEIVIKG-ADRQVVGQLA AEIRAVR------PPEPY---KGKGIRYADEKVTIKETK----------MIQTESRLDVADNTGAKSVLCIKVLG-SKRR Y--ASVGDIIKVSVKEAAPR-G-------RVKKGEVYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLN-SKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NSIKPADGA-KHAARRVG-RGIGSGL-GKTAGRGHKGQKSRSGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSISLTALVDVLALKNA-GLVGVK---------VIK--SGE-I-S-K-A-VKL- SGITATAGAKAAIEAAGGSL-K---EQK--GRN---TGVA-TRGNSVAFG----------DFGLKCT--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISTKPAEVRMGNGK---------GNPEYYVAEIQP-GKVVFEI--VG-- VPEELAREAFRLAAAKLPLRTTF-VKKEQRLRRARQTRIRI----AQQGVARLTVNRTNLHIYASVISG---D--GSKVL ASASTA-EADV-RKSL-GGSGKG-GNAAAAQIIGKRIAEK--AKAAG-VEKVAFDRAGFAYH--GRVKALADAAREAGLQ F-------------------------------------------------------------MSE-TRAVLRGVRLSVDK GRLVADLIRGKKVDQALNILAFT---------------------------------QKKAAVIVKKVLESAIAN----A- EHND-GADIDDLKVKTIFVEQGTTLKRFTARAKGRGNRISKPTCHIYVTVGNMNKIRKGDEVIVLTGR------DK-GKR GTVSLRKDDSH---LV--IEGINLVKKHVK----PN--PMKGTT-GGIVEKAMPIHQSNVA-IFNAAT-------GK--A --DRVGIKV---QA--------DGRVR---VFKSSG---AEI--MGQKIHPTGFRLA--VS-RNWASRWYA------SNR D--FAGMLAEDIKVREYL--KAKLK-----NAAVSRILIERPA-K-NARITIFSARPGVVIGKKGEDIENLKKELATRVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGTSEAKTTYGVIGVKVWVYMSMSDPIADLLTRIRNAQMVSKATVSV-PSSKVKVAIAQVLKDEGYIDGFE VKS----E---S----GKTELEITLKYY----AG-------R---PVIERIERVSRPGLRVYKGCGSIPQVMNGLGVAIV TTPKGVMTDRKARATGVGGEVLCYVAMSKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSDKRAKTVTVLVERRVKHPIYD KIMIKSSKYHAHDEN--GEYKMGDTIEITESRPLSKTKNWVATRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLVAKVEKAIA---TKDKK----PVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYVTD-QMVGH KLGEFALTRTFKGHP------A---DK----KVQ------KK >BETA_Herminiimonas_arsenicoxydans Concatenation of 2 sequences MALVKVKPTSPGRRGMVKVVNAD-LYKG------------RP-FAGLLEKKSKTAGRNNNGHITTRH-IGGGHKQH---- YRVIDFK-RT--K-DGIPAKVERIEYDPNRTANIALVLYA-DGERQYIIATKGMAVGDQLMNGS-E-AP-IKSGNCLPIR NIPVGTIMHCVEMLPGKGAQMARTAGAGVVLMAR--EGVYAQVRLRSGEVRRVHIECRATVGEVGNAEHSLRKIGKAGAM -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGR-HPVSP---WGQQTKGKKTR-RNKR-TT-S-MIVSRR --------------------------------KGQ---G-LLGRKVGMMRIFT-DDGD---------SIPVTVLDVSNNR VTQIK----TPD----V--DGY--SAVQVAF-------GS--RVNK----------ASAGHHK----------------- ---AG-VEAGTVLKEFRV------AATAASEL-----KV---GD-VIAA--S-L-FEVGQKVDVQGVTIGKGYAGTIKRH HFAS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVARTMQNLEIARIDADRQ---------------- ----------LLLVKGA-VPGAKNGQVIVS--MELKLLN-DQGQSS-SNVAAPDTIF----GR-DY-NEALIHQVVVAYQ ANARSGNRKQKDREE--------VH-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMYRAGLCSILSQLAREG----------------R-LSVIESL----SVD-A------ --PKTKLVI--TDSLD--E---NLLLASRNLPNVL-I---------------CEPRHADPVSLVFYKK----ILITKLAL AKIEARLQEFYKEKV----VGDLTAKFAYKSAMEVPRILKITLNMGLS-EAIADKKIIEHAVGDLTKIAGQKPVVTKARK AIAGFKIREGYPIGCMVTLRGAQMYEFLDRFITVALPRVRDFRGISG-KAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGMNISITTT-----------------------AKTDDEAKALLAAFKFPFMSRVG-K--MPIALPSGAEAT-I--- -T-A--E-QITVKGPLGSLSQAL--NG-L--VQIENAS-GT--LNF----K-P-ANDSREAN-AMSGTLRALVNNMVNGV TKGFEKKLMLVGVGF--RAAAQG-DK--LNLS--LGFSHPVVHAM-P-A-GIKVETP--T-QTEILIKG-IDRQSVGQVA AEVRAYR------PPEPY---KGKGVRYSDEVVVIKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--AGIGDVIKVTVKVAAPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLVKFDSNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NTIQPADGA-KHYKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVRLSDLIDILALKQA-GVIGVR---------VIL--SGE-L-T-K-K-VTL- KGLIATKGAKAAIEAAGGSV-K---EQK--GRN---TGISHSRGTAVSFG----------EFGLKAI--GRGRITARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISNKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VDEALAREAFRLAAAKLPLLTTF-VKKQSRLRRGRQTRAKI----AELKVIRLAVHRTNLHIYASIIGP---D---AKIL ASASTA-EAEV-RKELAGQSGAG-GNVAAAALVGKRVAEK--ALKAG-IAEVAFDRSGFRYH--GRVKAVAEAAREAGLK F--------------------------------------------------------------ME-TKAILKGVRLSDQK GRLVADQIRGKKVDAALNLLQFS---------------------------------PKKGAAIIKRVLESAIAN----A- EHND-GADIDELFVKTIYVEKGPILKRFTARAKGRGDRISKQSCHIYVTVGNMDKIRKSDEVIVLTGK------DK-GKR GVVQRRVDANY---LV--VEGVNVAKKATK----PN--PMTGAT-GGIVDKLMPIHVSNVA-LFNAAT-------GK--A --DRAGFKD----V--------DGKVR---VYKSSG---EAV--MGQKIHPTGFRLS--VT-RNWASRWYA------GNS N--FATMLNEDLKVRAYL--KTKLK-----NASVGRVIIERPA-K-NARITIYSSRPGVVIGKKGEDIEVLKSALTKMVH VNIEEIRK---PETDAQLIADSIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARKEWYREGRVPL- -HTLRAEIDYGFGEAETTYGIIGIKVWVYMSMSDPIADMLTRIRNAQVVQKTSVAM-PSSKVKIAIANVLKDEGYIEDYA VTE----A---A----GKAELKIGLKYY----AG-------R---PVIERLERVSRPGLRVYKGKDDIPNVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAAPNQKIRIRLKAFDYRLIDQSALEIVETAKRTGAVVKGPVPLPTRIQRFDVLRS PHVNKTSR-DQFEIRTHVRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGKVVSDKMDKTVTVLIERHVKHPLYG KIIMRSNKYHAHNEG--NQAKAGDTVEIQEGRPISKTKAWTVTRVVQAA------------------------------- -MTRSL-KKGPFCDA-HLVKKVETAQA---IKDKK----PIKTWSRRSTIMPDFIGLTIAVHNGKQHVPVYVSE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------K >BETA_Janthinobacterium_sp_Marseille Concatenation of 2 sequences MALVKVKPTSPGRRGMVKVVNAD-LYKG------------RP-FAGLLEKKSKTAGRNNNGHITTRH-IGGGHKQH---- YRVIDFK-R--TK-DGIPAKVERIEYDPNRTANIALVLYA-DGERQYIIATKGMAVGDQLMNGS-E-AP-IKSGNCLPIR NIPVGTVMHCVEMLPGKGAQMARTAGAGVVLMAR--EGTYAQVRLRSGEVRRVHIECRATVGEVGNAEHSLRKIGKAGAM -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGRH-PVSP---WGQQTKGKKTR-SNKR-TT-S-MIVSRR --------------------------------KGQ---G-LLGRKVGMMRIFT-DDGD---------SIPVTVLDVSNNR VTQIK----TSE----V--DGY--SAVQVAF-------GS--RVNK----------ASAGHFK----------------- ---AG-VEAGTVLKEFRV------AATAASEL-----KV---GD-VIAA--S-L-FEVGQKVDVQGVTIGKGYAGVIKRY NFGS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTRTTQNLEIARIDADRQ---------------- ----------LLLVKGA-VPGAKNGQVIVS--MELKLLN-DQGQAA-SNVAAPDTIF----GR-DY-NEALIHQVVVAYQ ANARSGNRKQKDREE--------VH-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PDENFSHKVNKKMYRAGVCSILSQLAREG----------------R-LSVIENL----SVE-A------ --PKTKLVI--TDSLD--E---NLLLASRNLPNVL-I---------------CEPRHADPVSLVFYKK----ILITKLAL AKIEARLQEFYKEKV----VGDLTAKFAYKSVMEVPRILKITLNMGLS-EAVADKKIIEHAVGDLTKIAGQKPVVTKARK AIAGFKIREGYPIGCMVTLRGAHMYEFLDRFITVALPRVRDFRGVSG-KAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGMNISITTT-----------------------AKTDDEAKALLAAFKFPFMSRVG-K--MPIALPSGAEAT-I--- -T-A--A-QITVKGPLGSLTQSL--NG-L--VNIENDN-GT--LNF----K-V--ANDREAN-AMSGTLRALVNNMVNGV TKGFEKKLTLVGVGY--RAAAQG-DK--LNLS--LGFSHPVVHQM-P-Q-GVKVETP--T-QTEILIKG-IDRQKVGQVA AEVRAYR------EPEPY---KGKGVRYSDEVVVIKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--AGIGDVIKVTVKVAAPR-G-------RVKKGEIYNAVVVRTAKGVRRQDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NSIQPADGA-KHYKRRVG-RGIGSGL-GKTSGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVRLSDLIDILALKQA-GVIGVR---------VIL--SGS-I-T-K-K-VTV- KGLIATKGAKAAIEAAGGSV-K---EQK--GRN---TGISHSRGTAVSFG----------EFGLKAI--GRGRITARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VDEALAREAFRLAAAKLPLLTTF-VKKQSRLRRGRQTRAKI----AELKVNRLAVHRTNLHIYASIIGP---D---ATVL ASASTL-EAEV-RQELAGQSGKG-GNVAAAALVGKRVAEK--ALKAG-IAEVAFDRSGFRYH--GRVKAVAEAAREAGLK F-------------------------------------------------------------MME-TKATLRGVRLSAQK GRLVADQIRGKKVDQALNILQFS---------------------------------PKKGAAIIKRVLESAIAN----A- EHND-GADIDELKVTTIYVEKGSVLKRFTARAKGRGDRISKQSCHIYVTVGNMDKIRKSDEVIVLTGK------DK-GKR GVVQRRVDANY---VV--VEGVNVAKKATK----PN--PMTGAT-GGIVDKLMPIHVSNVA-LFNAAT-------GK--A --DRAGFKD----V--------DGKVR---VYKSSG---EAV--MGQKIHPTGFRLA--VS-RNWASRWYA------G-N S-NFATMLNEDLKVRAYL--KTKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEVLKSALTKMVH VNIEEIRK---PETDAQLIADSIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARKEWYREGRVPL- -HTLRADIDYGFGEAETTYGIIGIKVWVYMSMSDPIADMLTRIRNAQVVQKTSVAM-PSSKVKIAIANVLKDEGYIEDFA VTE----A---A----GKAELKIGLKYY----AG-------R---PVIERLERVSRPGLRIYKGKDDIPNVMNGLGVAIV STPKGVMTDRKARATGVGGEVICYVAAPNQKIRIRLKAFDYRLIDQSALEIVDTAKRTGAVVKGPVPLPTRIQRFDVLRS PHVNKTSR-DQFEIRTHVRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGKVVSDKMDKTVTVLIERHVKHPLYG KIIMRSSKYHAHNEG--NQAKAGDTVEIQEGRPISKTKAWTVTRVVQAA------------------------------- -MTRSL-KKGPFCDA-HLVKKVETAQA---IKDKK----PIKTWSRRSTIMPDFIGLTIAVHNGKQHVPVYVSE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK------K- >BETA_Laribacter_hongkongensis_HLHK9 Concatenation of 2 sequences MALVKVKPTSAGRRAVVKVVNKD-LHKG------------AP-YAPLLEKQIQNAGRNNNGHITTRH-KGGGHKHH---- YRVVDFR-RN--K-DGIVAKVERIEYDPNRTAHIALLCYA-DGERRYIIAPRGLKAGAEVVNGA-E-AP-IKAGNCLPIR NIPVGTTIHCIEMQPGKGAQLARSAGASVMLLAR--EGSYAQLRLRSGEIRKVHIDCRATVGEVGNEEHSLRKLGKAGAT -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT-G--EGR-VPVSP---WGTPAKGYRTR-NNKR-TD-N-MIVRRR --------------------------------MSL---G-LVGRKVGMTRVFA-EDGQ---------SIPVTVLDMSANR VTQIK----TAD----T--DGY--NAVQVAY-------GS--KVLK----------AEAGHFK----------------- ---AG-VEAGRGLKEFTA------DAAKLAEL-----KV---GD-TLTV--E-L-FQVGQLVDVTGTSQGKGFSGVIKRH NFSS-NRASHGNSVTTRA-PGSIGQA-QDPG-RVFPGKRMAGQYGNVKRTVQSLEVVRIDAERQ---------------- ----------LLLIKGS-VPGSKGNDVVVL--MELKVIN-QQGQAV-ESLQAAETLF----GR-EY-NEALVHQVVTAYL ANARAGNRAQKDRSE--------IN-KSTKKPF---------RQKGTGRAR--------AGR---AS-SP----LW---- RGGGKVFPNS-PDENFSHKVNRKMFRAGMAAILSELLRSD----------------R-LVIIDDI----KVD-S------ --PKTKLVI--TGELD--E---NLYLSSRNLSNVL-V---------------IEASQADPYSLVRFDK----VVVTRDAV KQFEARLQEFYKTTV----VPKLVEQFGYKSVMEVPRIEKITLNMGVG-EAVADKKVLDFAVGDLQKIAGQKPVVTAAKK SIAGFKIREGYPVGCKVTLRRERMFEFLDRLVTVALPRVRDFRGVNG-KSFDGRGNYNMGVREQIIFPEIE-----YDKI DAVRGMNITITTT-----------------------AKTDEEARALLAAFKFPFMSRVA-K--NPVILPAGVEAK-F--- -T-A--A-EIVVKGPLGQLAMPL--NA-G--VEVRLED-NA--LKF----A-A--KDEKASR-SMSGTMRALVNNMVTGV SKGFERKLQLVGVGY--RAQAQG-AA--LNLT--LGFSHPVVHPM-P-E-GVAVETP--S-QTEIILKG-VDKQKVGQVA AEIRAYR------APEPY---KGKGVRYAGEQVVLKETK----------MIQMQTQLEVADNTGARRVMCIKVLG-SKRR Y--ATVGDIIKVSIKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMF-L--NTIKPGEGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVRLDDLIDFLALQQA-GLVPAK---------VIL--AGK-I-E-R-A-VTL- RGLLATAGAKAAIEAAGGQV-K---VHK--GRN---TGIA-TRGTKVSFG----------DFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRVFPDKPITKKPAEVRMGNGK---------GSVEYWVAEIQP-GKMLYEM--EG-- VSEELAREAFRLAAAKLPIATTF-VKKQARLRRARKTRARI----AELKMARLSVHRTNCHIYAQIIDE---T--GSRVL AQASTL-EAEV-KKEL----ANG-GNAGAAALIGKRIAEK--AKAAG-VEKVAFDRSGFQYH--GRIKALADAARENGLA F--------------------------------------------------------------MK-VSAVLKNARVSAQK ARLVADLIRGKSVEQALNTLTFT---------------------------------PKKSAVLMKKVLESAIAN----A- EHNE-GADIDTLKVATVYVDKGPSLKRFTARAKGRGNRIEKQTCHITLVVGNMQKIRKGDEVVVITGK------DK-GKR GTVLRVLPTEG--RVV--VEGVNVVKKHQK----PN--PVKGQA-GGIVDKTLSIDVSNVA-IFNPAT-------QK--A --DRVGVKT---LE--------DGKVR---VFKSNG---ELV--MGQKIDPRGFRLA--VT-RNWSSKWFA------NSQ N--FPGMLKEDIDVREFL--KAKLK-----NASVSRITIERPA-K-SARITIHTARPGVVIGKKGEDIEVLKQELQKRVH VNIEEVRK---PEIDAQIIADGIASQLEKRVMFRRAMKRAMQNAMRL-GALGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADVDYATSEAHTTYGVIGIKVWVYMSMHDPISDMLTRIRNAQRVTKASVAM-PSSKLKVAIAAVLKDEGYIEDFA VTG----E---E----KKPVLDIQLKYY----AG-------R---PVIERIERVSRPGLRIYKGSNDIPRVMNGLGVAIV STSKGVMTDRKARAAGIGGELLCIVAMQNQKIRIRLKAFDYHLIDRSAQEIVDTAKRTGAVVKGPVPLPTKIERFDILRS PHVNKTSR-DQFEIRTHLRLMDIIDPTDKTVDALMKLDLPAGVDVEIKLVRALTGKVVSDKMDKTVVVLVERKVKHPIYG KVIRLSKKYHAHDEA--NEYGIGDIVTISECRPLSKTKSWTVTALIEKA------------------------------- -MARSI-KKGPFVDL-HLLKKVDAARS---SNDKR----PIKTWSRRSTILPDFVGMTIAVHNGRTHVPVYVTE-NMVGH KLGEFSLTRTFKGHA------A---DK----KAK------R- >BETA_Leptothrix_cholodnii_SP-6 Concatenation of 2 sequences MAVVKVKPTSPGRRGVVKIVHKH-LHKG------------KP-EASLLEPQMQNAGRNNNGHITVRH-KGGGHKHH---- YRVVDFR-R--NK-DGIPAKVERIEYDPNRTAHIALICYA-DGERSYIIAPRGLEAGQTVLNGA-E-AP-IKAGNTLPIR NIPVGSTIHCVEMMPGKGAQIARSAGTSVTLMAR--EGIYAQVRLRSGEVRKIHIDCRATIGEVSNEEHNLRQYGKAGAK -RWL-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----GEGQAPVSP---WNTLTKGYRTR-NNKRTQT---FIVSRR --------------------------------QRL---G-LLGRKVGMMRIFT-DDGD---------AVPVTVLDVSNNR VAQIK----TVE----T--DGY--SAVQVAF-------GA--RVTK----------PEAGHLK----------------- ---AG-VESGELLQEFRV------SAEVAAEC-----KP---GS-QLPI--A-M-FQAGQQVDVQGTTIGKGFAGTIKRH HFGS-QRASHGNSRSHNV-PGSISMA-QDPG-RVFPGKKMSGHLGDDTVTTQNLDVVRVDEARQ---------------- ----------LLLVKGA-VPGAKGGFVTVR--MQLELLN-EQGQAT-AKVDAPDTVF----AR-DY-NESLIHQIVVAYQ ANARQGTRAQKDREQ--------VH-HSTKKPF---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRIFPNS-PDENFTQKVNKKMYRAGMASIFSQLAREG----------------R-LAVIDSI----TLD-A------ --PKTKLVI--ADEVD--E---NLFLASRNLANVL-V---------------VEPRYADPLSLVFYKK----ILVTKAAI DKLQARLQAFYLETV----VPSLVEKFGYKSVMQVPRFEKITLNMGVS-EAVSDKKVMDHAVSDLTKIAGQRPVVTKSRK AIAGFKIREDVPIGCMVTLRGVRMFEFLDRFVTIALPRVRDFRGISG-RSFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKTDDECKALLTAFRFPFMSRVG-K--MLVAVPQGVDVS-I--- -N-E--D-LISVKGSLGTLLRPA--HR-L--VKVQNEA-GK--LSF----T-P--LDEAEAN-AMSGTMRALVANMVNGV SKGFQKKLSLVGVGY--RAQAQG-QK--LNLQ--IGFSHPVVKEM-P-E-GIKVECP--T-QTEILIKG-ADRQVVGQLA AEVRAFR------PPEPY---KGKGIRYSDEKVAIKETK----------MIQMQSRLDVADNTGAKSVMCIKVLG-SKRR Y--AGIGDVIKVSIKDAAPR-G-------RVKKGEVYNAVVVRTAKGVRRQDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NSIKPGSGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRAGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSITLGQLVDLLLLKQI-GLVGVK---------VVK--SGE-L-T-R-A-VVL- KGIGATAGAKAAIEAAGGSL-K---EQK--GRN---TGVA-TRGANVSFG----------EFGLKAT--ERGRLTARQIE AARRAISRHI------KRGGRIFIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKVLYEL--NG-- VPEDLAREAFTLAAAKLPLRTTF-VKKEQRLRRSRQTRARI----ALQGVERLTVFRTNLHIYASVISA---D--GGKVL ASASTA-EKEV-RAQL-GVAGKG-ACVDAAQLIGKRIAER--AKAAG-VEKVAFDRSGFAYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------ME-TQAIVRGVRLSCDK GRLVADLIRGKKVGLALDILTFT---------------------------------QKKAAGIIKKALESAIAN----A- EHND-GADIDELRVTSIYVEQGATLKRFSARAKGRGNRISKPTAHIYVTVGNMNKILKGDEVIVLTGR------DK-GKR GKIAVRVDEDH---VL--VDGVNVVKKHVR----PN--PLKGTT-GGIVDKTMPIHQSNVA-IYNPAS-------GK--A --DRVGIKL---LA--------DGKVR---VFKSSG---EEI--MGQKIHPTGFRLP--VT-RNWSSRWYA------NNR N--FAGMLAEDIEVREFL--KKKLK-----NAAVSRVTIERPA-K-NARITIYSARPGVVIGKKGEDIENLKLELAKMVA VNIEEVRK---PEVDAQLIAESITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGTAEAKTTYGVIGVKVWVYMSMSDPIADMLTRIRNAQMVEKTSVAM-PSSKLKSAIAQVLKDEGYIDGFA VKT----T---D----GKSQLEISLKYY----AG-------R---PVIERIERVSRPGLRIYKGRHDIPTVMNGLGVAIV TTPQGVMTDRKARAAGIGGEVLCYVAMQKQKIRIRLKAFDYKLIDQSAQEIVETAKRTGAIVKGPVPLPTRMQRFDILRS PHVNKTSR-DQFEMRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLTRTLVGKVVSDKRAKTVTVLVERRAKHELYG KIVARSRKYHAHDEN--GDYKMGDVVEISESRPLSKTKNWVVTRLVEKA------------------------------- -MSRSL-KKGPFVDH-HLLAKVEKAVA---IKDKK----PVKTWSRRSTILPEFIGVTIAVHNGKQHVPVYVTD-QMVGH KLGEFALTRTFKGHP------A---DK----KAK-------R >BETA_Methylibium_petroleiphilum_PM1 Concatenation of 2 sequences MAVVKVKPTSPGRRAVVKVVHSH-LHKG------------KP-EASLLEPQIQNAGRNNNGHITIRH-KGGGHKHH---- YRVVDFK-R--NK-DGIPAKVERIEYDPNRTAHIALVCYA-DGERRYIIAPRGLEVGATILSGS-E-AP-IKAGNTLPIR NIPVGSTMHCVELLAGKGAQIARSAGTSVTLLAR--ESTYAQVRLRSGEVRRIHIECRATIGEVSNEEHNLRQYGKAGAI -RWK-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----GEGQVPVSP---WNTMTKGYRTR-SNKR-TQ-T-FIVSRR ----------------------------MRSVDRL---G-LLGRKVGMMRIFT-DDGD---------AVPVTVLDVSNNR VTQVK----TVE----T--DGY--SAIQVTF-------GA--RVTK----------PEAGHLK----------------- ---AG-VEAGEILREFAV------SAEVAAEY-----KP---GG-TLPV--G-L-FAAGQKVDVQGTSIGKGFTGTIKRH NFGS-QRASHGNSRSHNV-PGSISMA-QDPG-RVFPGKKMSGHRGDVTKTTQNLDIVRVDEARQ---------------- ----------LLLVRGA-VPGAKNGFVTVR--MELELLN-EQGQAA-SKVDAPDTVF----GR-DY-NEALVHQVVVAYQ ANARQGTRAQKDRQT--------VK-HSTKKPW---------RQKGTGRAR--------AGM---TS-SP----LW---- RGGGRIFPNS-PEENFSHKVNKKMYRAGMAAIFSQLAREG----------------R-LAVVDSI----KVE-T------ --PKTKLVI--ADEVD--E---NLFLASRNLANVL-V---------------IEPRYADPLSLVFYKK----VLVTKGAI EKLKARLQQHYRDKI----VADLVAKFGYKSVMQVPRLTKITLNMGVS-EAVSDKKVMEHAVGDLTKIAGQKPVVTKSKK AIAGFKIRDGVPIGCMVTLRGVRMYEFLDRFVTISLPRVRDFRGISG-RSFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGMNISFTTT-----------------------AKTDDECKALLAAFKFPFMSRVG-K--MPIAVPKGVDVA-I--- -N-A--D-QISVKGSLGTLVRPV--NR-L--VSVKNED-GK--LSF----A-P--ADEAAAN-AMSGTMRALVANMVNGV SKGFERKLTLVGVGF--RAQAQG-AK--LNLQ--VGFSHPVVKDM-P-A-GIKVECP--T-QTEIVIKG-SDRQVVGQIA AEVRAIR------PPEPY---KGKGIRYAEEKVSLKETK----------MIQMQSRLDVADNTGAKSVMCIKVLG-SKRR Y--AGIGDVIKVSIKEAAPR-G-------RVKKGEVYSAVVVRTAKGVRRQDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLME-L--NTIKPASGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRAGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVTLADLVDVPTLKQA-GLVGVK---------VIK--SGE-L-S-K-K-VVL- KGIGATAGAKAAIEAAGGSV-K---EQK--GRN---TGIA-TRGANVSFG----------DFGLKAT--ERGRLTARQIE AARRAISRHV------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKVLYEI--NG-- VPEELAREAFTLAAAKLPLRCTF-VRKDQRLRRSKQTRVRI----ALQKVARLTVFRSNLHIYASVISD---D--GSKVL ASASTA-EKEV-RARL-GAAGKG-GNTEAAALIGKRIAER--AKAAG-IESVAFDRGGFAYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------ME-TRAIVRGVRLSVDK GRPVADLVRGKKVDQALNILEFT---------------------------------QKKAAVIIKKALESAIAN----A- EHND-GADIDELKVKTIHVEQGATLKRFSARAKGRGNRISKPTCHIFVTVGN---------------------------- -------------------------------------------------------------------------------- --------------------------------------------MGQKIHPVGFRLP--VT-RNWSSRWYA------SNR N--FATMLAEDLKVREYL--KAKLK-----SAAVSRILIERPA-K-NARITIYSARPGVVIGKKGEDIENLKAELTRRVA VNIEEVRK---PEIDAQLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGFSEAKTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKAVVVM-PSSKLKVAIAQVLKDEGYIDAYA VKG----E---A----EKPQLEIGLKYY----AG-------R---PVIERIERVSRPGLRVYKGRHEIPQVMNGLGVAIV TTPKGVMTDRKARAAGIGGEVLCYVAMQKQKIRIRLKAFDYKLIDQSALEIVDTAKRTGAIVKGPVPLPTRMQRFDILRS PHVNKSSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLTRTLVGRVVSDQRSKTITVLVERRVKHELYG KIVARSRKYHAHDEN--NEYKLGDLVEIAEGRPISKTKAWVVTRLVEKA------------------------------- -MARSL-KKGPFVDH-HLVAKVEKAVA---IKDKK----PIKTWSRRSTILPDFIGLTIAVHNGKQHVPVYVTD-QMVGH KLGEFALTRTFKGHP------A---DK----KAK------K- >BETA_Methylobacillus_flagellatus_KT Concatenation of 2 sequences MALIKVKPTSPGRRSVVKVVTPE-LHKG------------KP-YAPLLEKQSKKAGRNNNGHITTRH-QGGGHKQH---- YRIVDFR-RN--K-DGIPAKVERLEYDPNRSAHLALLVYA-DGERRYIIAPRGVSVGAQLVSGS-D-AP-IRAGNALPLR NIPVGSTIHCIELQPGKGAQVARSAGTSVQLLAR--EGSYAQLRLRSGEVRRVHVDCKATIGEVGNEEHSLRSIGKAGAV -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGM-NPVSP---WGLPTKGYRTR-SNKR-TD-N-MRVSRR --------------------------------MSL---G-LIGRKVGMTRIFT-DEGE---------SVPVTVLEVVPNR VTQIK----TAA----S--DGY--TSLQVAY-------GE--RIGK----------ALAGHYK----------------- ---AG-VSAGAGIKEFPV------SDDVLANY-----SV---GG-QITV--E-L-FQPGQLVDVTGTSLGKGFSGAIKRH NFSS-NRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMPGHLGAVKTTVQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGSKGGDVVVR--MEIKLID-KNGRPAKAGLAVSEATF----GR-EF-NEALVHQVVVAYQ ANARTATRAQLTRAE--------VS-HTTKKPW---------NQKGTGRAR--------AGM---SS-ST----IW---- RGGGRAFPNT-PDENFSHKINRKAYRAGVRSILSELVRQD----------------R-LSAVEEF----AVD-T------ --PKTKLVL--VDKFD--E---NLYLSARNLPHVL-V---------------LEAQYVDPVSLVRFPQ----VLATAGAV KKLEARLKDFYKDTV----VKQLVEQFGYKSVMEVPRIEKITLNMGVG-EAVADKKVMENAVADLEKIAGQKAVVTKAKK SIAGFKIRDGYPVGCKVTLRREHMYEFLDRLITVAIPRIRDFRGISP-KSFDGRGNYNLGVREQIIFPEIE-----YDKI DALRGLNITITTT-----------------------AKTDEEARALLSAFSFPFMSRVA-K--NPVAIPAKVEVV-L--- -S-S--D-NIAVSGPLGKLSLPL--SG-D--VAIERDG-DN--LTF----A-A--ASEQHAR-AMSGTLRSLVFNMVTGV SQGFTRKLTLLGVGY--KAQAQG-AN--LNLD--LGFSHPVSHKM-P-D-GVTVQTP--S-PTEIVLTG-ADKQVVGQVA AQIRAYR------APEPY---KGKGVRYADEVVIIKETK----------MIQMQSRLDVADNTGARSVMCIKVLG-SKRR Y--AGIGDIIKVSVKDAAPR-G-------RVKKGEVYSAVVVRTAKGVRRPDGSLVKFDSNAAVLLN-NKLE-PIGTRIF GPVTRELR-GERFMKIVSLAPEVLMK-L--NTIKPAEGA-KHARRRVG-RGIGSGL-GKTGGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FNSVRTADLIDILALKQA-NVIPVK---------VYL--SGD-V-T-R-A-VTV- QGLALSKGARAAVEAAGGKI-K---MQK--GRN---KGIA-TTGNKVSFG----------EFGLKAI--GRGRLTARQIE AARRVMTRHI------KRGGRVWIRVFPDQPISKKPAEVRMGNGK---------GSTEYYIAQIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPIETTF-INVNSRLRRARKTRAKI----AELKAIRLSVHRSNCHIYAQIIAE---T--GDKVL ASASTL-EVEV-RKDI----KNG-GNIAAAALVGKRIAEK--AKAAG-ITTVAFDRSGYKYH--GRIKALADAAREHGLS F--------------------------------------------------------------ME-VSAVLRGVHLSPQK ARLVADLVRGKKVDQALNILAFT---------------------------------PKKGAEVIKKVVESAIAN----A- EHNE-GADIDELKVTSIYVDKGLVLKRIRARAKGRAGRIIKPTCHITVTVGNMSKIRKGDEVILNTGK------DK-GKR GTVLRVLPTGQ---VL--VEGINVVKKHAK----PN--PMRGIA-GGIISKEMPVDISNVA-LFNRAT-------QK--G --DRVGFKT---LD--------DGKVR---VFKSSG---EVV--MGQKIHPFGFRLS--VQ-KNWSSRWYA------NSN N--FPAMLSSDIKVREFL--KKKLA-----HAAVSKIVIERPA-K-NAKITIYSARPGIVIGKKGEDIESLRSGLQGLVH LNIEEVRK---PEIDATLIAESIAQQLEKRVMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGVAEAKTTYGIIGIKVWVFMSMSDPIADMLTRIRNAQSTNKVSVSM-PSSKLKRAIAAVLKDEGYIDDFS VQD----V---D----GKPQLNISLKYY----AG-------R---PVIEKIERVSRPGLRIYRGNQEIPVVMHGLGVTIV STSKGVMTDRKARDAGVGGEVLCVVAMAAQKIRIRLKAFDYRLIDQSALEIVETAKRTGAVVKGPVPLPTRIERFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLVRTLSGRVVSDKMDKTVTVLVERKVKHPLIG KVVRRSNKFHAHDEN--NECKEGDLVMIEESRPLSKTKTWRVSKIVEKA------------------------------- -MARSI-KKGPFVDG-HLAKKVEAAVA---SRDRK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVLISE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------R >BETA_Neisseria_gonorrhoeae_FA_1090 Concatenation of 2 sequences MAIVKMKPTSAGRRGMVRVVTEG-LHKG------------AP-YAPLLEKKNSTAGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-R--NK-DGISAKVERIEYDPNRTAFIALLCYA-DGERRYIIAPRGIQAGVVLVSGA-E-AA-IKVGNTLPIR NIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAK--EGAYAQVRLRSGEVRKINVDCRATIGEVGNEEQSLKKIGKAGAN -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGRT----GEAREPVSP---WGTPAKGYRTR-NNKRTDN---MIVRRR --------------------------------MTL---G-LVGRKVGMTRVFD-EQGV---------SVPVTVLDMSANR VTQVK----SKD----T--DGY--TAVQVTF-------GQ--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLIEFAL------TEEKLAEL-----KA---GD-EITV--S-M-FEVGQLVDVTGTSKGKGFSGTIKRH NFGA-QRTSHGNSRSHRV-PGSIGMA-QDPG-RVFPGKRMAGQYGNTKATVQKLEVVRVDAERQ---------------- ----------LLLVKGA-VPGAVNSDVVVR--MELKVID-AKGQVS-GSLSVSDALF----AR-EY-NEALVHQLVNAYL ANARSGNRAQKTRAE--------VK-HSTKKPW---------RQKGTGRAR--------SGM---TS-SP----LW---- RKGGRAFPNK-PDENFTQKVNRKMYRAGMATILSQLARDE----------------R-LFVIEAL----TAE-T------ --PKTKLFV--TKRLD--E---NVYLASRNLPNVL-V---------------LEAQQVDPYSLLRYKK----VIITKDAV AQLEARLREFYKETV----VPELVKQFGYKSVMEVPRIEKITLNMGVG-EAVADKKVMEHAVSDLERIAGQRPVVTVARK SIAGFKIRDNYPVGCKVTLRRDQMFEFLDRLITIALPRVRDFRGVSG-KSFDGRGNYNMGVREQIIFPEIE-----YDKI DALRGLNITITTT-----------------------AKTDEEAKALLSLFKFPFMSRVA-K--NPVTVPAGVEVK-F--- -G-T--E-ALVIKGKNGELSFPL--HS-D--VAIEFND-GK--LTF----V-A--NNSKQAN-AMSGTARALVSNMVKGV SEGFEKKLQLMGVGY--RAQAQG-KI--LNLS--LGFSHPIVYEM-P-E-GVSVQTP--S-QTEIVLTG-SDKQVVGQVA SEIRAFR------APEPY---KGKGVRYVGEVVVMKEAK----------MIQMQTILDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIKVAVKDAVPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLN-NKLE-PLGTRIF GPVTRELR-TERFMKIVSLAPEVLMF-L--NTIQPAVGA-THAGRRVG-RGIGSGL-GKTGGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSLRLSELIDILVLKQA-GLIAVK---------VIA--SGE-I-S-K-A-VAL- KGIKVTKGARAAIEDVGGKI-K---QQK--GRN---TGIA-TRGNKVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRVFPDKPITEKPIQVRMGGGK---------GNVEYYIAEIKP-GKVLYEM--DG-- VPEELAREAFELAAAKLPIPTTF-VKHTTRLRRARKTRARI----ADLKMVRLCVFRSNNHIYAQVISA---E--GDKVL AQASTL-EAEV-RGSL----KSG-SNVEAAAIVGKRIAEK--AKAAG-VEKVAFDRSGFQYH--GRVKALAEAARENGLS F--------------------------------------------------------------MR-VNAQHKNARISAQK ARLVADLIRGKDVAQALNILAFS---------------------------------PKKGAELIKKVLESAIAN----A- EHNN-GADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCHINVTVGNMNKIIKGDRVVVIAGK------DK-GKQ GQVVRVLGG----KVV--VEGVNVVKRHQK----PN--PMRGIK-GGIITKEMPLDISNIA-ILNPET-------NK--A --DRVGIKL---IE-------NEGRVR---FFKSNG---SII--MGQKINPTGFRLA--VT-KDWASKWFA------KST D--FSTVLKQDIDVRNYL--RQKLA-----NASVGRVIIERPA-K-SARITIHSARPGVVIGKKGEDIEVLKRDLQVLIH VNIEEIRR---PELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRS-GAKGIKIMTSGRLNGADIARSEWYREGRVPL- -HTLRANVDYATSEAHTTYGVLGLKVWVYMSMHDPISDMLTRIRNAQRANKAAVAM-PSSKLKCAIAKVLKEEGYIEDFA VSS----D--------VKSILEIQLKYY----AG-------R---PVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIAIV STSKGVMTDRKARSQGVGGELLCIVAMANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRS PHVNKTSR-EQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKVVRTLQGKVVSDKMDKTVTVLVERKVKHSLYG KIIRLSTKIHAHDEN--NQYGIGDVVVISESRPLSKTKSWVVSELVEKA------------------------------- -MARSL-KKGPYVDL-HLLKKVDAVRA---SNDKR----PIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISD-NMVGH KLGEFSLTRTFKGHL------A---DK----KAK------KK >BETA_Neisseria_gonorrhoeae_NCCP11945 Concatenation of 2 sequences MAIVKMKPTSAGRRGMVRVVTEG-LHKG------------AP-YAPLLEKKNSTAGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-R--NK-DGISAKVERIEYDPNRTAFIALLCYA-DGERRYIIAPRGIQAGVVLVSGA-E-AA-IKVGNTLPIR NIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAK--EGAYAQVRLRSGEVRKINVDCRATIGEVGNEEQSLKKIGKAGAN -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGRT----GEAREPVSP---WGTPAKGYRTR-NNKR-TD-N-MIVRRR -----------------------------------------------MTRVFD-EQGV---------SVPVTVLDMSANR VTQVK----SKD----T--DGY--TAVQVTF-------GQ--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLIEFAL------TEEKLAEL-----KA---GD-EITV--S-M-FEVGQLVDVTGTSKGKGFSGTIKRH NFGA-QRTSHGNSRSHRV-PGSIGVA-QDPG-RVFPGKRMAGQYGNTKATVQKLEVVRVDAERQ---------------- ----------LLLVKGA-VPGAVNSDVVVR--MELKVID-AKGQVS-GSLSVSDALF----AR-EY-NEALVHQLVNAYL ANARSGNRAQKTRAE--------VK-HSTKKPW---------RQKGTGRAR--------SGM---TS-SP----LW---- RKGGRAFPNK-PDENFTQKVNRKMYRAGMATILSQLARDE----------------R-LFVIEAL----TAE-T------ --PKTKLFV--TKRLD--E---NVYLASRNLPNVL-V---------------LEAQQVDPYSLLRYKK----VIITKDAV AQLE----------------------------MEVPRIEKITLNMGVG-EAVADKKVMEHAVSDLERIAGQRPVVTVARK SIAGFKIRDNYPVGCKVTLRRDQMFEFLDRLITIALPRVRDFRGVSG-KSFDGRGNYNMGVREQIIFPEIE-----YDKI DALRGLNITITTT-----------------------AKTDEEAKALLSLFKFPF-----------MTVPAGVEVK-F--- -G-T--E-ALVIKGKNGELSFPL--HS-D--VAIEFND-GK--LTF----V-A--NNSKQAN-AMSGTARALVSNMVKGV SEGFEKKLQLIGVGY--RAQAQG-KI--LNLS--LGFSHPIVYEM-P-E-GVSVQTP--S-QTEIVLTG-SDKQVVGQVA SEIRAFR------APEPY---KGKGVRYVGEVVVMKEAK----------------------------------------- -----------MAVKDAVPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLN-NKLE-PLGTRIF GPVTRELR-TERFMKIVSLAPEVL-------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------MFRSNNHIYAQVISA---E--GDKVL AQASTL-EAEV-RGSL----KSG-SNVEAAAIVGKRIAEK--AKAAG-VEKVAFDRSGFQYH--GRVKALAEAARENGLS F--------------------------------------------------------------MR-VNAQHKNARISAQK ARLVADLIRGKDVAQALNILAFS---------------------------------PKKGAELIKKVLESAIAN----A- EHNN-GADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCHINVTVGN-----------MLGGK------------ --------------VV--VEGVNVVKRHQK----PN--PMRGIK-GGIITKEMPLDISNIA-ILNPET-------NK--A --DRVGIKL---IE-------NEGRVR---FFKSNG---SII--MGQKINPTGFRLA--VT-KDWASKWFA------KST D--FSTVLKQDIDVRNYL--RQKLA-----NASVGRVIIERPA-K-SARITIHSARPGVVIGKKGEDIEVLKRDLQVLIH VNIEEIRR---PELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRS-GAKGIKIMTSGRLNGADIARSEWYREGRVPL- -HTLRANVDYATSEAHTTYGVLGLKVWVY--------------------------------------------------- -------------------------------------------------------------------------------- --------------------------MANQKIRIRLKAYDYALIDRFAQEIVETAKRTGAVVKGPIPLPTKIERFNILRS PHMNKTSR-EQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKVVRTLQGKVVSDKMDKTVTVLVERKVKHSLYG KIIRLSTKIHAHDEN--NQYGIGDVVVISESRPLSKTKSWVVSELVEKA------------------------------- -----------------MLKKVDAVRA---SNDKR----PIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISD-NMVGH KLGEFSLTRTFKGHL------A---DK----KAK------KK >BETA_Neisseria_meningitidis_053442 Concatenation of 2 sequences MAIVKMKPTSAGRRGMVRVVTEG-LHKG------------AP-YAPLLEKKNSTAGRNSNGHITTRH-KGGGHKHH---- YRVVDFK-R--NK-DGIPAKVERIEYDPNRTAFIALLCYA-DGERRYIIAPRGIQAGAVLVSGA-E-AA-IKVGNTLPIR NIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAK--EAAYAQVRLRSGEVRKINVNCRATIGEVGNEEQSLKKIGKAGAN -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGRT----GEAREPVSP---WGTPAKGYRTR-NNKRTDN---MIVRRR --------------------------------MTL---G-LVGRKVGMTRVFD-EQGV---------SVPVTVLDMSANR VTQVK----SKD----T--DGY--TAVQVTF-------GQ--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLIEFAL------TEEKLAEL-----KA---GD-EITV--S-M-FEVGQLVDVTGISKGKGFSGTIKRH NFGA-QRTSHGNSRSHRV-PGSIGMA-QDPG-RVFPGKRMAGQYGNTKATVQKLEVVRVDAERQ---------------- ----------LLLVKGA-VPGAVNSDVVVR--MELKVID-AKGQVS-GSLSVSDALF----AR-EY-NEALVHQLVNAYL ANARSGNRAQKTRAE--------VK-HSTKKPW---------RQKGTGRAR--------SGM---TS-SP----LW---- RKGGRAFPNK-PDENFTQKVNRKMYRAGMATILSQLTRDE----------------R-LFAIEAL----TAE-T------ --PKTKLFV--TKQLD--E---NVYLASRNLPNVL-V---------------LEAQQVDPYSLLRYKK----VIITKDAV AQLEARLREFYKETV----VPELVKQFGYKSVMEVPRIEKITLNMGVG-EAVADKKVMEHAVSDLEKIAGQKPVVTVARK SIAGFKIRDNYPVGCKVTLRRDQMFEFLDRLITIALPRVRDFRGVSG-KSFDGRGNYNMGVREQIIFPEIE-----YDKI DALRGLNITITTT-----------------------AKTDEEAKALLSLFKFPFMSRVA-K--NPVTVPAGVEVK-F--- -G-T--E-ALVIKGKNGELSFPL--HS-D--VAIEFND-GK--LAF----V-A--NNSKQAN-AMSGTARALVSNMVKGV SEGFEKRLQLIGVGY--RAQAQG-KI--LNLS--LGFSHPIVYEM-P-E-GVSVQTP--S-QTEIVLTG-SDKQVVGQVA AEIRAFR------APEPY---KGKGVRYVGEVVVMKEAK----------MIQMQTILDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIKVAVKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLN-NKLE-PLGTRIF GPVTRELR-TERFMKIVSLAPEVLMF-L--NTIQPAVGA-THAGRRVG-RGIGSGL-GKTGGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSLRLSELIDILVLKQA-GLIAVK---------VIA--SGE-I-S-K-A-VAL- KGIKVTKGARAAIEAVGGKI-K---QQK--GRN---TGIA-TRGNKVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRVFPDKPITEKPIQVRMGGGK---------GNVEYYIAEIKP-GKVLYEM--DG-- VPEELAREAFELAAAKLPIPTTF-VKHTTRLRRARKTRARI----ADLKMVRLCVFRSNNHIYAQVISA---E--GDKVL AQASTL-EAEV-RGSL----KSG-SNVEAAAIVGKRIAEK--AKAAG-VEKVAFDRSGFQYH--GRVKALAEAARENGLS F--------------------------------------------------------------MR-VNAQHKNARISAQK ARLVADLIRGKDVAQALNILAFS---------------------------------PKKGAELIKKVLESAIAN----A- EHNN-GADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCHINVTVGNMNKIIKGDRVVVIAGK------DK-GKQ GQVVRVLGD----KVV--VEGVNVVKRHQK----PN--PMRGIE-GGIITKEMPLDISNIA-ILNPET-------NK--A --DRVGIKL---IE-------NEGRVR---FFKSNG---SII--MGQKINPTGFRLA--VT-KDWASKWFA------KST D--FSTVLKQDIDVRNYL--RQKLA-----NASVGRVVIERPA-K-SARITIHSARPGVVIGKKGEDIEVLKRDLQVLVH VNIEEIRR---PELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRS-GAKGIKIMTSGRLNGADIARSEWYREGRVPL- -HTLRANVDYATSEAHTTYGVLGLKVWVYMSMHDPISDMLTRIRNAQRANKAAVAM-PSSKLKCAIAKVLKEEGYIEDFA VSS----D--------VKSILEIQLKYY----AG-------R---PVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIAIV STSKGVMTDRKARSQGVGGELLCIVAMANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRS PHVNKTSR-EQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKVVRTLQGKVVSDKMDKTVTVLVERKVKHPLYG KIIRLSTKIHAHDEN--NQYGIGDVVVISESRPLSKTKSWVVSELVEKA------------------------------- -MARSL-KKGPYVDL-HLLKKVDAARA---SNDKR----PIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISD-NMVGH KLGEFSLTRTFKGHL------A---DK----KAK------KK >BETA_Neisseria_meningitidis_Z2491 Concatenation of 2 sequences MAIVKMKPTSAGRRGMVRVVTEG-LHKG------------AP-YAPLLEKKNSTAGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-R--NK-DGIPAKVERIEYDPNRTAFIALLCYA-DGERRYIIAPRGIQAGAVLVSGA-E-AA-IKVGNTLPIR NIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAK--EGAYAQVRLRSGEVRKINVNCRATIGEVGNEEQSLKKIGKAGAN -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGRT----GEAREPVSP---WGTPAKGYRTR-NNKR-TD-N-MIVRRR --------------------------------MTL---G-LVGRKVGMTRVFD-EQGV---------SVPVTVLDMSANR VTQVK----SKD----T--DGY--TAVQVTF-------GQ--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLIEFAL------TEEKLAEL-----KA---GD-EITV--S-M-FEVGQLVDVTGTSKGKGFSGTIKRH NFGA-QRTSHGNSRSHRV-PGSIGMA-QDPG-RVFPGKRMAGQYGNTKATVQKLEVVRVDAERQ---------------- ----------LLLVKGA-VPGAVNSDVVVR--MELKVID-AKGQVS-GSLSVSDALF----AR-EY-NEALVHQLVNAYL ANARSGNRAQKTRAE--------VK-HSTKKPW---------RQKGTGRAR--------SGM---TS-SP----LW---- RKGGRAFPNK-PDENFTQKVNRKMYRAGMATILSQLTRDE----------------R-LFAIEAL----TAE-T------ --PKTKLFV--TKQLD--E---NVYLASRNLPNVL-V---------------LEAQQVDPYSLLRYKK----VIITKDAV AQLEARLREFYKETV----VPELVKQFGYKSVMEVPRIEKITLNMGVG-EAIADKKVMEHAVSDLEKIAGQKPVVTVARK SIAGFKIRDNYPVGCKVTLRRDQMFEFLDRLITIALPRVRDFRGVSG-KSFDGRGNYNMGVREQIIFPEIE-----YDKI DALRGLNITITTT-----------------------AKTDEEAKALLSLFKFPFMSRVA-K--NPVTVPAGVEVK-F--- -G-T--E-ALVIKGKNGELSFPL--HS-D--VAIEFND-GK--LTF----V-A--NNSKQAN-AMSGTARALVSNMVKGV SEGFEKRLQLIGVGY--RAQAQG-KI--LNLS--LGFSHPIVYEM-P-E-GVSVQTP--S-QTEIVLTG-SDKQVVGQVA AEIRAFR------APEPY---KGKGVRYVGEVVVMKEAK----------MIQMQTILDVADNSGARRVMCIKVLG-SKRR Y--ASVGDIIKVAVKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLN-NKLE-PLGTRIF GPVTRELR-TERFMKIVSLAPEVLMF-L--NTIQPAVGA-THAGRRVG-RGIGSGL-GKTGGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSLRLSELIDILVLKQA-GLIAVK---------VIA--FGE-I-S-K-A-VAL- KGIKVTKGARAAIEAVGGKI-K---QQK--GRN---TGIA-TRGNKVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRVFPDKPITEKPIQVRMGGGK---------GNVEYYIAEIKP-GKVLYEM--DG-- VPEELAREAFELAAAKLPIPTTF-VKHTTRLRRARKTRARI----ADLKMVRLCVFRSNNHIYAQVISA---E--GDKVL AQASTL-EAEV-RGSL----KSG-SNVEAAAIVGKRIAEK--AKAAG-VEKVAFDRSGFQYH--GRVKALAEAARENGLS F--------------------------------------------------------------MR-VNAQHKNARISAQK ARLVADLIRGKDVAQALNILAFS---------------------------------PKKGAELIKKVLESAIAN----A- EHNN-GADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCHINVTVGNMNKIIKGDRVVVIAGK------DK-GKQ GQVVRVLGD----KVV--VEGVNVVKRHQK----PN--PMRGIE-GGIITKEMPLDISNIA-ILNPET-------NK--A --DRVGIKL---IE-------NEGRVR---FFKSNG---SII--MGQKINPTGFRLA--VT-KDWASKWFA------KST D--FSTVLKQDIDVRNYL--RQKLA-----NASVGRVVIERPA-K-SARITIHSARPGVVIGKKGEDIEVLKRDLQVLVH VNIEEIRR---PELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRS-GAKGIKIMTSGRLNGADIARSEWYREGRVPL- -HTLRANVDYATSEAHTTYGVLGLKVWVYMSMHDPISDMLTRIRNAQRANKAAVAM-PSSKLKCAIAKVLKEEGYIEDFA VSS----D--------VKSILEIQLKYY----AG-------R---PVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIAIV STSKGVMTDRKARSQGVGGELLCIVAMANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRS PHVNKTSR-EQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKVVRTLQGKVVSDKMDKTVTVLVERKVKHPLYG KIIRLSTKIHAHDEN--NQYGIGDVVVISESRPLSKTKSWVVSELVEKA------------------------------- -MARSL-KKGPYVDL-HLLKKVDAARA---SNDKR----PIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISD-NMVGH KLGEFSLTRTFKGHL------A---DK----KAK------KK >BETA_Nitrosomonas_europaea_ATCC_19718 Concatenation of 2 sequences MALRKTKPTSPGRRAVIKSVNSF-IYKG------------KP-FAALTEKKKKNAGRNNSGRITVRH-IGGGHKQH---- YRIVDFC-R--NK-DDIPAKVERIEYDPNRSAYIALLCYA-DGERRYIIAAKDIEVGSYLVSGS-S-SP-IKMGNAMPIR NIPVGSVIHCIELRPGKGAQLARSAGSSAQLMAK--EGDYSQIRLRSGEIRKIHISCRATIGEVSNSEHNLQSIGKAGAI -RWR-----GVR-P-TVRGVAMNPIDHPHGGGEGKT----AAGRHPVSP---WGTPSKGSRTR-KNKRTSN---MIVRSR --------------------------------MKL---G-LIGKKIGMTRVFT-ESGN---------SIPVTVLDVSGNR VVQVK----TEE----K--DGY--SAVQLTQ-------GY--RITK----------ALSGHFQ----------------- ---AG-VEAGTVIKEFRV------DHDIGSDI-----KI---GS-EISV--E-L-FEVGSKVDVCGISIGKGYAGTIKRH NFSS-SRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKKMTGHLGNAQCTVQNIEVVRVDAGRG---------------- ----------LLFLKGS-VPGSKGNGVFIR-MVKIPCIY-ENGQI--EDIEASESVF----GR-VY-NEALVHQVVKSYL ANARAGTRAQKGRSD--------VT-GSTRKQW---------RQKGTGRAR--------TGA---AT-NP----LW---- RGGGKIFPNK-PTENFKQKLNRKMYRAGMCTIFSELLRNN----------------K-LVAIDEF----QIE-M------ --PKTKMII--TSEID--S---NLYLASRNLPNLK-V---------------VEVDLIDPVSLLAYDN----VVITRDTV NKIEARLLEYYRDTV----TKELTQKFNYKTVMEVPKITKITLNMGVG-EASTDKKIIENAVSDLEKISAQKPVVTKARK SIATFKVRQGYPVGCKVTLRGVKMYEFLDRLVNVAIPRIRDFRGIQV-KGFDGRGNFNMGIKEQIIFPEID-----YDKI DKVRGLNITVTTT-----------------------AKTDQEARALLSAFKFPFSVFVT-T--KPIEIPKSVEVQ-L--- -T-E--F-GVFIKGPLGSLFQAI--DA-H-NAKIVVSS-DQ--LTI----E-A--LNAKQTK-SIVGTLKALISNMIKGV TAGFEKKLLIIGVGY--KAQAAG-NI--LNLN--LGFSHPVAYTV-P-E-GIKVETP--S-TTEILIKG-IDKQKVGQVA AEVRSYR------RPEPY---KGKGIRYFDEKVTIKETK----------MIQMQSLLKVADNTGARTVMCIKVLG-SKRR F--AGIGDVIKVAVKDAAPR-G-------RIKRGEVYNAVIVRTAKGIRRADGSLVKFDTNAAVILN-NKLE-PIGTRIF GPVTRELR-TAKFMKIVSLAPEVIMK-L--NTIKPGIGS-AKPKRRVG-RGIGSGL-GKTCGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FTVIKLSTLFNPSVLYDH-GLIKVK---------IIL--GNQLI-K-R-A-IKI- KDLIISRGAKEAVEQMGGLV-K---QHK--GRN---TGIA-TRGAKVSFG----------EFGLKAI--GRGRLTSRQIE AARRAMTRHI------KRGGRIWIRVFPDKPVSQKPAEVRMGKGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VDESLAREAFRLAAAKLPMQTTF-VTKQMRLRRAKATRIKI----GNSRQFRLSVHKSNNHIYAQILDP---S--SNRVI VSASTV-EAEV-KKQY----PSG-GTIEAAKYVGHLVAKK--SIESQ-IYEVAFDRSGFKYH--GRIKALADAARSAGMK F--------------------------------------------------------------ME-TSAVLRSVRLSAQK GRLVADQIRGLQVERAIRLLTFS---------------------------------PKKGASIILKLLESAVAN----A- EHNE-GADIDELKISQIFIGQGATLKRVSPRAKGRGNRISKPTCNIFLTVSNMKKIRKGDSVIVIAGK------DK-GKQ STVIRFQSTER---VI--VREVNKVKSHIK----PN--PNRNIA-GGIVETEKPLHISNIA-IFNPEK-------NK--A --DRVGFRF---NE--------SGKVR---YFKSDG---TLI--MGQKINPTGFRLS--VL-KNWSSRWYT------NTK K--FSDFLNEDISVRQYL--QKKLA-----HASVGSIIIERPS-K-NAKITIHTSRPGVVIGKKGEDIEILRRNVEKLVH INIEEIRK---PEIDAQLIAASITQQLEKRIMFRRAMKRAIQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRAEVDYGTSEARTTYGIIGVKVWVFMCMTDPIADMLTRIRNAQSAEQKEIKM-PSSKLKKAILKILKEEGYIENFQ EDP----N---H----KKPSISVILKYF----NG-------E---PVITSISRVSKPGLRSYKSKNDLPRVMNGLGVAIV STSKGVMTERTARMAGVGGELLCVVTMQNQKIRIRLKAFDYRLIDKSAIEIVETAKRTGAVVKGPVPLPTRIERFDVLRS PHVNKTSR-DQFEIRTHLRLMDIIDPTDKTVDALMKLDLPAGVDVEIKLSKTLIGQVVSDKRDKTVTVRIDRKVKHPLYG KIVTRSSKYHAHDEL--NQYKLGDIVAISETRPKSKTKAWQVVRVI-KV------------------------------- -MSRSV-SKGPFVDL-HLVNKVLSARQ---NNDKK----PIKTWSRRSTILPDFIGLTISVHNGRQHVPVFVTE-NMVGH KLGEFSHTRTFKGHA------G---DK----KAA-----GSK >BETA_Nitrosomonas_eutropha_C71 Concatenation of 2 sequences MTLKKSKPTSPGQRAVVRSVNSF-LYKG------------NS-YSALTEKKKKNSGRNNSGKITVRH-IGGGHKHH---- YRIVDFC-R--NK-DDIPAKVERIEYDPNRSAYLALLCYA-DGERKYIIAAKDIEVGSYVVNGS-G-SP-VKTGNALPIR NIPVGSVIHCIELKPGKGAQLARSAGSSAQLMAR--EGDYSQIRLRSGEIRKIHINCRATIGEVGNSEHNLQSIGKAGAV -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRH-PVSP---WGTPSKGSRTR-RNKRTVN---MIVRSR --------------------------------MKL---G-LIGKKVGMTRIFT-ESGS---------SVPVTVLDVSKNR VVQIK----TAE----R--DGY--SAIQLTQ-------GY--RITK----------ALSGHFR----------------- ---AG-VEAGKVIKEFRI-----EQQAINSDL-----KL---GS-EINV--E-I-FLTGSKVDVSGVSIGKGYAGTIKRH NFSS-SRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKKMTGRLGGVNSTIQNIEVVRVDTVRG---------------- ----------LIFLKGS-VPGSKGNGVFIR-MVKIPCRS-ENGQVV--NIEVSDSVF----DR-VY-NEALVHQIVTSYL ANARSGTRAQKGRSE--------VA-GSTRKQW---------RQKGTGRAR--------VGA---AS-NP----LW---- RGGGKIFPNK-PTENFTKKVNRKMYRAGMCTIFSQLLRNS----------------K-LVAISEF----RVE-T------ --TKTKMII--TDEVD--E---NLYLASRNVPNIK-V---------------VEIDLIDPVSLLSYDN----VVITREAV NKIEARLFDHYKNIV----IKELIQQFNYKTVMQVPKITKITLNMGVG-EAAVDKKIMENAVSDLEKISAQKPIITKAKK SIATFKIRQGYPVGCMVTLRGIKMYEFLDRLVSIAIPRIRDFRGIGG-KGFDGHGNFNMGIKEQIIFPEID-----YDKI DKLRGLNITMTTT-----------------------AKTDIEAKALLSAFKFPFSFYTT-T--KPIEIPKLVEVQ-L--- -T-E--L-GIAIKGPLGSLFQLI--DV-H-NTKIEMSS-NY--LTI----Q-A--LNSKQAR-SIVGTINALISNMIRGV TNGFEKKLLIVGVGY--KAQVSG-NI--LNLN--LGFSHPISYSV-P-E-DIKVETP--N-PTEILIKG-IDKQKVGQVA ADVRSYR------RPEPY---KGKGIRYFDEKVIIKETK----------MIQMQSLLKVADNTGARTVMCIKVLG-SKRR F--AGIGDVIKVAVKDAAPR-G-------RIKKGEVYNAVIVRTAKGIRRSDGSLVKFDTNAAVILN-NKLE-PIGTRIF GPVTRELR-TAKFMKIVSLAPEVIMR-L--NTIKPGMGS-TKPRRRVG-RGIGSGL-GKTCGRGHKGQKSRAGGF-H--- -KIGF-E-GGQMPLQRRLPK-RG--FVVIKLSSLFDTSVLHEF-NLIKVK---------IIA--DAQAC-T-R-A-IRL- KDLRVTRGVKDIVEHAGGQV-K---QHK--GRN---TGMA-TRGAKVSFG----------EFGLKAI--GRGRLTSRQIE AARRAMTRHI------KRGGRIWIRIFPDKPVSRKPAEVRMGKGK---------GNPEYYVAEIQP-GKVLYEM--DG-- VDELLAREAFRLAAAKLPMQTVF-VIKQARLRRAKATRIKI----SNSKRFRLLVHKSNNHIYAQILDP---S--SNNVV VSASTV-EAEV-KKQY----PNG-GTVEAARYIGQLVAKK--SLDSQ-ISEIAFDRSGFKYH--GRIKALADAARSAGMK F--------------------------------------------------------------ME-TSVVLRSVRLSAQK GRLVVNQIRGLQVDQAIKLLTFS---------------------------------PKKGAVIILKLLESAVAN----A- EHNE-GADIDELKVARVFIGQGSSLKRVSPRAKGRGNRISKPTCNIFLTVCNMKKIRKGDNVIILSGK------DK-GKQ STVIKFESVEK---VI--VRDVNRVKSHVK----PN-PSK-NIV-GGIVEIEKPIHVSNIA-IFNSDK-------NK--A --DRVGFRF---NE--------SGKVR---YFKSDG---TLI--MGQKINPTGFRLS--VL-KNWSSRWYA------NTK K--FSVFLNEDINVRQYL--QKRLA-----HASVGSIIIERPS-R-NAKITIHTSRPGVVIGKKGEDIEILRKNVEKLVH INIEEIRK---PEIDAQLIAASITQQLEKRIMFRRAMKRAIQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRAEVDYGTSEAKTTYGVIGVKVWVFMCMTDPIADMLTRIRNAQAAEKKEVKI-PSSKLKKAILKILKDEGYIESYQ EIV----S---D----GKLSVDICLKYF----NG-------G---PVISSLTRISKPGLRRYSSRNNLPKVMHGLGIAIV STSKGVMTERSARAGGVGGELLCIVAMQNQKIRIRLKAFDYRLIDKSAVEIVETAKRTGAVVKGPVPLPTRIERFDVLRS PHVNKTSR-DQFEIRTHLRLMDIIDPTDKTVDALMKLDLPAGVDVEIKLSKYLIGQIISDKRDKTVTVRIDRKVKHPLYG KIITRSKKYHAHDEH--NQYKVGDVVAISEARPISKTKSWRVIKVV-KI------------------------------- -MSRSI-SKGPFVDL-HLINKVIVVRK---NNDKR----PIKTWSRRSTILPDFIGLTISVHNGRQHIPIFITE-NMVGH KLGEFSHTRTFKGHA------G---DK----KAA-----GSK >BETA_Nitrosospira_multiformis_ATCC_25196 Concatenation of 2 sequences MALVKVKPTSPGRRAVVKVVNAG-LHKG------------AP-YPHLVEKQNRTAGRNNKGQITTRH-IGGGHKQH---- YRIVDFR-RN--K-DGIAARVERLEYDPNRSANLALLCYS-DGERRYVIAPKGIVPGMQLMSGA-D-AP-IKNGNALPLR NIPVGSIIHCVEMMPGKGAQLARSAGASVQLLAR--EGDYAQLRLRSGEIRRVHVNCRATIGEVGNEEHNLRAIGKAGAQ -RWR-----GIR-P-TVRGVAMNPIDHPHGGGEGKT-A--AGR-HPVSP---WGTPSKGFRTR-VNKR-TD-G-MIVRRR --------------------------------MSL---G-LVGRKVGMTRIFT-EEGD---------SQPVTVLDVSNNR VTQIK----TPA----T--DGY--SAVQVTF-------GK--RVNK----------PSAGHFK----------------- ---AA-VEAGEILREFRV------AEEILGTL-----SP---GT-VIGL--D-I-FQPGQRVDVTGTSIGKGYAGAIKRH GFAS-NRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGNVRRTIQNLEILRIDAERG---------------- ----------LLIIKGA-IPGSKGGDVTVS--MELKLID-YNGQSS-ASVSASETLF----GR-EY-NEALVHQVVTAYL ANARSANRAQKARSD--------VA-KSTRKPW---------RQKGTGRAR--------AGM---AS-SP----LW---- RGGGKIFPNS-PEENFSHKVNRKMYRAGIGAILSQLVREN----------------R-LSVVENF----IVD-A------ --PKTKMII--TDNID--E---NLYLSSRNLPLVK-V---------------VEAGYADPVSLMRFAN----VLITRNAL AKMEARLQEYYRSTV----VQQLMEQFGYKSVMEVPRIRKITLNMGVG-EAVADKKIMDNAVGDMQKIAGQKPVVTKARK SIATFKVRDGYPVGCMVTLRRVRMYEFLDRLVNIAIPRIRDFRGISG-RSFDGRGNYNMGIKEQIIFPEIE-----YDKI DALRGMNITITTT-----------------------AKTDAEAKALLAAFKFPFMSRVG-K--NPVSVPANVEVR-L--- -S-G--S-EVEVKGPLGMLRHEL--VS-D--ISIERKG-ES--LLV----K-A--ADDKHAN-AMWGTTRALLANMVKGV TTGFEKRLILVGVGY--RAQAAD-NV--LNLT--LGFSHPIAHKM-P-E-GIKVETP--S-QTEVVIKG-MDKQQVGQVA ADVRAYR------EPEPY---KGKGVRYADEVIVLKETK----------MIQMQSILQVADNTGARSLMCIKVLG-SKRR Y--AGIGDIIKVSVKDVAPR-G-------RVKKGEVYNAVVVRTSKGVRRADGSLIKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TARFMKIVSLAPEVLMQ-L--NSIKPAPGA-KHPKRRVG-RGIGSGL-GKTAGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FVSVRLSALIDILILKQA-GLVSVK---------VIL--SGK-I-E-R-A-VKL- QGIPVTKGAKAAIEAAGGSV-K---QQK--GRN---KGIA-TRGAKVSFG----------EYGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISHKPAEVRMGNGK---------GNPEYFVAEIQP-GKVLYEM--DG-- VDEVLARQAFRLAAAKLPILTTF-VSIESRLRRARQTRAKI----AELKVVRLAIHRSNSHIYAQLIDG---S--GSKVL ASASTL-EPEL-RKEL----PNG-GTVTAAAVVGKRVAEK--ARGLG-IETVAFDRSGFKYH--GRVKALADAARENGLK F--------------------------------------------------------------ME-TTAVLRGVRLSEQK GRLVADQIRGLPVERALNLLAFS---------------------------------PKKAAVIIRKLLESAIAN----A- EHNE-GADIDELKVSRIYVDRGPSLMRTSARAKGRGNRIVKPTCHILLTVGDMSKIKKGDDVIVIAGK------DK-GKR GTVLRVMKPDL---VV--VEGVNRLKKHQR----PN-PNK-GDT-GGIVEMDSPIQVSNIA-IYNPAT-------RK--A --DRIGFKT---VE-------GKGKAR---CFRSNE---ELI--MGQKIHPTGFRLS--VL-KNWSSKWYA------NGK S--FPGMLNEDIKVREYL--KKKLA-----HASVGRVVIERPS-K-NARITIYSSRPGVVIGKKGEDIEVLRGALQKLVH VNIEEIRK---PEIDAQLIADNIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADLDYGVSEAKTTYGVIGIKVWVFMSMSDPIADMLTRIRNAQLSEKTSVVM-PASKLKAAIAQVLKDEGYVEDFI VHE----A---G----GKSILDISLKYY----AG-------R---PVIERIERVSRPGLRIYKGSNKLPNVMNGLGVAIV STSKGVMTERKARANGVGGEVLCIVAMQSQKIRIRLKAFDYRLIDKSALEIVETAKRTGAVVKGPVPLPTRIERFDVLRS PHVNKTSR-DQFEIRTHLRLMDIMDPTDKTVDALMKLDLPAGVDVEIKLNRTLSGKVVSDKMNKTITVLVERKVKHPLYG KIMVRSKKYHVHDEA--NEFHTGDVVVIEECRPLSKTKAWRVVKLMQKA------------------------------- -MARSI-KKGPFVDL-HLLSKVEAARE---ANDKR----PIKTWSRRSTVLPDFIGLTIAVHNGKQHVPVYVTE-NMVGH KLGEFSHTRTFKGHS------G---DR----KAA-----GRK >BETA_Polaromonas_naphthalenivorans_CJ2 Concatenation of 2 sequences MAVIKMKPTSPGMRGMVKISRDH-LHKG------------EP-YAPLLEPQFQHSGRNNNGHITVRH-KGGGHKHH---- YRVVDFK-RN--K-DAIPAKVERIEYDPNRTAHIALICYA-DGERAYIIAPRGLEVGATILSGS-E-AP-IRVGNTLPIR NIPVGSTIHCIEMQIGKGAQIARSAGTSATLLAR--EGTYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRRLGKAGVK -RWM-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-G--EGR-HPVDP---WGNLTKGYRTR-NNKR-TQ-V-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------TVPVTVVDVSNNR VTQVK----TEA----N--DGY--DALQVAF-------GS--RVTK----------PEAGHLK----------------- ---AG-VEAGEILKEFRV------TADVAGKY-----AA---GT-VVPA-AD-I-FAVGQLVDVQGTSIGKGFAGTIKRH KMSS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTKTTQNLDIVRIDEARQ---------------- ----------LLMIRGA-VPGSKGGFVTVR--MQVELLN-DQGLSS-SKVDVSDTVF----GR-EY-NESLIHQVIVAFQ ANARQGTRAQKDREQ--------VR-HSTKKPF---------KQKGTGRAR--------AGM---TS-SP----LW---- RGGGRIFPNM-PDENFTHKINKKMYRAGMASIFSQLAREG----------------R-LAVVDSL----TVD-S------ --PKTKLVI--ADQVD--E---NLYLASRNLVNIL-V---------------VEPRYADPLSLVHYKK----VLVTKAAM DQLKARLQDQYREKI----APALIEKFGYTTPMQVPRITKITLNMGVS-EAVADKKVMDNAVADMAKIAGQKPVVTKAKK AIAGFKIREDLPIGCMVTLRGVQMYEFLDRFVTVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKTDEECKALLTAFRFPFMSRVA-K--MPVAIPEGVEIA-I--- -K-D--T-QINVKGALGALALAQ--NA-H--VVIASND-GK--LTF----V-P-ANDSRQAN-AMSGTMRQLVNNMVVGV TKGFQKKLNLVGVGF--KAQAQG-DK--LNLT--VGYSHPVVMAM-P-A-GITVATP--T-PTEVVIKG-SDRQRVGQIA AEVRAVR------PPEPY---KGKGIRYSDEKITIKETK----------MIQTQSKLDVADNTGAKSVMCIKVLG-SKRR Y--ASVGDVIKVSIKEAAPR-G-------RVKKGEVYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLME-L--NTITPGQGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGY-H--- -KVGF-E-GGQMPMQRRLPK-RG--FKSVTLTALVDLLTLKQS-GLVGVK---------IIN--TGS-L-S-L-A-VKL- TGISATAGAKTIIEAAGGSI-K---EQK--GRN---TGVA-TRGNSVAFG----------DFGLKCT--DRGRLTARQLE AARRAISRHV------KRGGRIWIRVFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKIVFEI--VG-- VTEELAREAFRLASAKLPLRTTF-VKKEQRLRRSRQTRIRI----ANQGVARLSVNRTNLHIYASVISG---D--GTKVL ASASTA-EVEV-RNEI-GGSGKG-GNVAAAQAIGKRIAEK--AKAAG-VEKVAFDRAGFAYH--GRVKALADAAREAGLQ F--------------------------------------------------------------ME-TRATLRGVRLSVDK GRLVADLIRGKKVDQALNILNFT---------------------------------QKKAAGIIKKVVESAIAN----A- EHND-GADIDELRVKTIYVEQGATLKRFSARAKGRGNSISKPTCHVYVVVGNMNKIRKGDEIIVITGR------DK-GKR GTISLRVDDSY---VL--VDGINLVKKHTK----PN--PLKGTT-GGIVEKSMPIHQSNVA-IFNAAS-------GK--A --DRVGIKL---LA--------DGKTR---VFKSSG---EEI--MGQKINPTGFRLS--IS-RNWSSRWYA------NNR D--FAGMLAEDIKVREYL--KKKLK-----NAAVSRVLIERPA-K-NARITIFSARPGVVIGKKGEDIEALKKELSRQVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GALGIKIMSSGRLNGIEIARCEWYREGRVPL- -HTLRADIDYGTSEAQTTYGIIGVKVWVYMSMSDPIADMLTRIRNAQMVEKAVVLV-PSSKVKVAIAQVLKDEGYIDGFS VKA----N---D----GKPQLEIALKYY----AG-------R---PVIERIERVSRPGLRVYKGHGAIPQVMNGLGVAIV TTPQGVMTDRKARATGTGGEVLCYVAATKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGKVVSDKRAKTVTVLVERRVKHELYG KIVSLSSKYHAHDEK--GEFKTGDVIEITESRPISKTKNWVVTRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLVAKADKAVT---NKDKK----PIKTWSRRSMILPEFIGLTIAVHNGKQHVPVYITD-QMVGH KLGEFALTRTFKGHP------A---DK----KVV------RK >BETA_Polaromonas_sp_JS666 Concatenation of 2 sequences MAVIKMKPTSPGMRGMVKISRDH-LHKG------------EP-YAPLLEPQFQKSGRNNNGHITVRH-KGGGHKHH---- YRVVDFK-RN--K-DAIPAKVERIEYDPNRTAHIALLCYA-DGERTYIIAPRGLEVGATLISGS-E-AP-IRVGNTLPIR NIPVGSTIHCIEMQIGKGAQIARSAGTSATLLAR--EGTYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRRLGKAGVK -RWM-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-G--EGR-HPVDP---WGNLTKGYRTR-NNKR-TQ-V-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------TVPVTVVDVSNNR VTQVK----TEA----N--DGY--DALQVAF-------GA--RVTK----------PAAGHLK----------------- ---AG-VEAGEILKEFRV------TADVAGKY-----AA---GT-VVPA-AD-V-FAVGQLVDVQGTSIGKGYAGTIKRH NMSS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTVTTQNLNIVRIDEARQ---------------- ----------LLMIRGA-VPGSKGGFVTVR--MQVELLN-DQGLAS-SKVDVPDTVF----GR-EY-NESLIHQVVVAFQ ANARQGTRAQKDREQ--------VR-HSTKKPF---------KQKGTGRAR--------AGM---TS-SP----LW---- RGGGRIFPNM-PDENFTQKINKKMYRAGMASIFSQLAREG----------------R-LAVVDSL----AVD-S------ --PKTKLVI--ADVVD--E---NLYLASRNLVNIL-V---------------VEPRYADPVSLVHYKK----VLVTKAAM DQLKARLQDQYREKI----APSLIEKFGYTSPMQVPRITKITLNMGVS-EAVADKKVMDNAVSDMTKIAGQKPVVTKAKK AIAGFKIREDLPIGCMVTLRGVQMYEFLDRFVTVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKTDEECKALLTAFRFPFMSRVG-K--MPVTLPQGVDVA-I--- -K-D--D-QINVKGALGALALTQ--NA-L--VTIKNDA-GK--LTF----A-P-ANDSREAN-AMSGTMRQLVNNMVTGV TKGFEKKLSLIGVGY--KAQAQG-AK--LNLT--VGYSHPVIMDM-P-A-GITVATP--T-PTEVVIKG-SDRQRVGQIA AEVRAVR------PPEPY---KGKGIRYADEKITIKETK----------MIQTQSKLDVADNTGAKSVMCIKVLG-SKRR Y--ASVGDVIKVSIKEAAPR-G-------RVKKGEVYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLME-L--NGIKPSLGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRAGGY-H--- -KVGF-E-GGQMPMQRRLPK-RG--FKSVTLSALVDLLALKTA-GLVGVK---------VIK--SGE-L-S-K-A-VKL- NGISATAGAKAIIEAAGGSV-K---EQK--GRN---TGVA-TRGNSVAFG----------DFGLKCT--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKIVFEI--VG-- VPEELAREAFRLASAKLPLRTTF-VKKEQRLRRSRQTRIRI----ATQGVARLTVNRTNLHIYASVISG---D--GTKVL AAASTA-EVEV-RKEI-GASGKG-GNVAAAQAIGKRIAEK--AKAAG-VEKVAFDRAGFAYH--GRVKALADAAREAGLQ F--------------------------------------------------------------ME-TRATLRGVRLSVDK GRLVADLIRGKKVDQALNILNFT---------------------------------QKKAAGIIKKVVESAIAN----A- EHND-GADIDELKVKTIYVEQGATLKRFSARAKGRGNSISKPTCHVYVVVGNMNKIRKGDEVIVIAGR------DK-GKR GTVSLRKDDSH---VL--VDGINLVKKHTK----PN--PLKGTT-GGIVEKSMPIHQSNVA-IFNAAT-------GK--A --DRVGIKL---LA--------DGKVR---VFKSSG---DEI--MGQKINPTGFRLA--VS-RNWASRWYA------S-N R-DFAGMLAEDIKVREYL--KAKLK-----NAAVSRVLIERPA-K-NARITIFSARPGVVIGKKGEDIENLKKELSRQVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GALGIKIMSSGRLNGIEIARCEWYREGRVPL- -HTLRADIDYGTSEAKTTYGVIGVKVWVYMSMSDPIADMLTRIRNAQMVEKAVVLV-PSSKVKVAIAQVLKDEGYIDGFS VKT----D---D----GKSQLEIALKYY----AG-------R---PVIERIERVSRPGLRVYKGHGAIPQVMNGLGVAIV TTPQGVMTDRKARATGIGGEVLCYVAATKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGKVVSDKRAKTVTVLVERRVKHELYG KIVSLSSKYHAHDEK--GEYHTGDVIEITESRPISKTKNWVVTRLVEKA------------------------------- -MTRSL-KKGPFVDH-HLVAKADKAVT---NKDKK----PIKTWSRRSMILPEFIGLTIAVHNGKQHVPVYITD-QMVGH KLGEFALTRTFKGHP------A---DK----KVV------KK >BETA_Polynucleobacter_necessarius_STIR1 Concatenation of 2 sequences MPLMKTKPTSPGRRSMVKVVNPD-LHKG------------KP-FASLLEPQFQKAGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN-DK-DGIPAKVERLEYDPNRSANIALILFA-DGECRYIPAAKGMTVGQAIMNGS-E-AP-IKSGNNLPIR NIPVGSTIHCVEIMPGKGAQVARSAGGSAVLLAR--EGVYAQVRLRSGEVRRVLIDCRATIGEVGNEEHSLRQIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT-G--EGR-VPVSP---WGTPTKGYRTR-RNKR-TT-S-MIVQRR --------------------------------MSL---G-LIGRKVGMTRLFT-DEGE---------AIPVTVIDVSDNR VAQIK----TQA----T--NGY--DAIQLAH-------GT--RVTK----------AMAGHFK----------------- ---AG-VMAGNALNEFHL------DAAKIAEM-----TP---GQ-VIPA--ETA-FTAGQKVDVQGVTIGKGYAGTIKRY HFAS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDITRTVQNLVIARIDAERN---------------- ----------LIMVKGA-IPGAPGGKVIVT--MELKLLQ-DNGILG-AGVQASPEVF----ER-EY-NEALVHQVVVAYQ ANARSGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMYRAGMRSILSQLAREG----------------R-LNVIDQF----NLD-A------ --PKTKLII--VDQVS--E---NLYLASRNLHKVA-V---------------VEPQHADPLALVQYKK----VLVSKAAI TKIETRFQEHYQSKV----VADLIAKFGYKSVMEVPRITKVTLNMGLG-DAVNDKKIIENAVGDLTKVAGQKPVVTKAKK AIAGFKIRQGYPIGAMVTLRSSRMYEFLDRFVTVALPRVRDFRGISG-KAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKTDEEAKALLAAFKFPFMSRVG-K--SPITVPKGAEIS-I--- -N-G--A-NITVKGPLGTLTHNL--HP-S--VGLKQED-GV--LTV----V-L--NNDPEAG-AQSGTARALVNNMVVGV TTGFERKLSLVGVGY--RAAAQG-ET--LKLQ--LGFSHDIIYNL-P-K-GVKAETP--S-QTEIIIKG-SNKQQVGQVA AEVRAYR------SPEPY---KGKGVRYVDEVVHLKETK----------MIQTESRLQVADNTGASEVLCIKVLG-SERR Y--ASIGDVIKVSVKSAAPR-G-------RVKKGDIYNAVVVRTAKGVRRPDGSLIKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVIMQ-L--NTIKPAEGS-KKNRRHVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPMYRRLPK-RG--FVSVTLNDLVDLLVLKAH-GFAGVK---------VIK--TGE-L-K-I-A-VTL- KGITATAAAKAAIEAAGGKL-K---EQK--GRN---TGVA-TRGSSVAFG----------DFGLKAV--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKVLYEM--DG-- VDEQLAREAFKLAAAKLPLQTTF-VKDESRQRRARQTRIRI----AEAQANRLTVIRSNSHISAQVYSP---C--GTKVV AAASTM-EKDL-RQAI----KNG-SYAEAAKQIGKLVAER--AVKAG-VVDVAFDRSGHRYH--GRIKALAEAAREAGLK F-------------------------------------------------------------MME-VKAIHKGARISAQK TRLVADQIRGLPIARALNILNFS---------------------------------PKKAAFIVKKVVESAVAN----A- EHNK-GADIDELKVSAIIVDKGTSLKRFTARAKGRGNQIEKQTCHISVTLSNMKKIRKGDSVVLLTGR------DK-GKQ GIVTAVLEN----KLV--IEGVNIYKKSVK----PN--PAAGVT-GGIIDKTMPVHISNVA-LVD-GN-------GK--P --SRVGIKL----V--------DGKQR---FLKTTG---ATL--MGQKINPTGFRLA--VT-KNWTSRWYA------NNT D--FAKMLKEDVDVRSYL--KKKLK-----NASVSKVVIERPA-K-SARITIYSSRPGVVIGKKGEDIEVLRRELQKRVH ANIEEIRK---PEVDAQLIADSITQQLEKRIMFRRAMKRAMQKAMRL-GAQGIKIMSSGRLNGAEIARREWYREGRVPL- -HTLKADIDYATSEAETTYGIIGVKVWVYMSISDPIADMLTRIRNAQAVQKPLVTM-PSSKVKVAIAKVLQDEGYIENFE IKG----E---A----AKPVLHIDLKYY----AG-------H---PVIERIDRVSTPSLRIYKGRHDIPEVMNGLGIAII STPQGVMTDRKARATGVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAVVKGPVPLPTRIERFDILRS PHVNKTSR-DQLEIRTHLRLMDIVDPTEKTVDALMKLDLPAGVGVEIKLRRTLVGRVVSDKMQKTVTVLVERQVKHPVIG KYVGQSKKYHAHDEA--GTYKMGDTVEIAESKPISRTKSWVVTRLVEAS------------------------------- -MTRSA-KKGPFCDT-SLVKKVEVAQA---NKDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVSE-NMVGH KLGEFALTRTFKGHA------A---DK----KVT------KK >BETA_Polynucleobacter_sp_QLW-P1DMWA-1 Concatenation of 2 sequences MPLMKTKPTSPGRRSMVKVVNPD-LHKG------------KP-FAPLLEPQFQKAGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN-DK-DGIPAKVERLEYDPNRSANIALIVFA-DGERRYIPAAKGMTVGQSLMSGS-E-AP-IKSGNNLPIR NIPVGSTIHCVEIMPGKGAQVARSAGGSAVLLAR--EGVYAQVRLRSGEVRRVLIECRATIGEVGNEEHSLRVIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-G--EGR-VPVSP---WGTPTKGYRTR-RNKR-TT-S-MIVQRR --------------------------------MSL---G-LIGRKVGMTRLFT-DEGD---------SIPVTVIDVSDNR IAQIK----TQA----T--DGY--DAIQLAH-------GT--RVTK----------AMAGHFK----------------- ---AG-VMAGNGLNEFQL------DAAKIAEM-----TP---GQ-VIPA--DTA-FTAGQKVDVQGVSIGKGYAGTIKRY HFAS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTRTVQNLVIARIDAERN---------------- ----------LIMVKGA-IPGAPGGKVIVT--MELKLLQ-DNGTLG-AGVQASPEVF----ER-EY-NEALVHQVVVAYQ ANARSGNRAQKDREQ--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMYRAGMRSILSQLAREG----------------R-LNVVDQF----SLD-A------ --PKTKLII--VDQVS--E---NLYLASRNLHKVA-V---------------CEPQHADPLALVQYKK----VLVSKAAI AKIETRFQEHYQEKV----VADLITKFGYKSVMEVPRITKVTLNMGLG-DAVNDKKIIENAVGDLTKVAGQKPVVTKAKK AIAGFKIRQGYPIGAMVTLRGQRMYEFLDRFVTVALPRVRDFRGISG-KAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKTDEEAKALLAAFKFPFMSRVG-K--SPITVPKGAEIS-I--- -N-G--A-NVTVKGPLGTLTHNL--HP-S--VGLKQED-GV--LTV----V-L--NNDPEAG-AQSGTARALVNNMVVGV TTGFERKLSLVGVGY--RAAAQG-ET--LKLQ--LGFSHDIIYNL-P-K-GVKAETP--T-QTEIIIKG-SNKQQVGQVA AEVRAYR------SPEPY---KGKGVRYVDEVVHLKETK----------MIQTESRLQVADNTGASEVLCIKVLG-SKRR Y--ASIGDVIKVSVKSAAPR-G-------RVKKGDIYNAVVVRTAKGVRRPDGSLIKFDANAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVIMQ-L--NTLKPAEGS-KKNRRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPMYRRLPK-RG--FVSITLNDLVDLLVLKAH-GFAGVK---------VIK--TGE-L-K-I-A-VTL- KGLTATAGAKAAIEAAGGKL-K---EQK--GRN---TGVA-TRGSSVAFG----------DFGLKAV--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKVLYEM--DG-- VDEQLAREAFKLAAAKLPLQTTF-VKDESRQRRARQTRIRI----AEAQANRLTVIRSNTHISAQVYSP---C--GTKVV AAASTM-EKDL-RQAI----KNG-GNAQAAAQIGKLVAER--AVKAG-VVDVAFDRSGHRYH--GRIKALAEAAREAGLK F--------------------------------------------------------------ME-VKAIHKSARISAQK TRLVADQIRGLPIARALNILNFS---------------------------------PKKAAFIVKKVVESAMAN----A- EHNK-GADIDELKVSTIIVDKGTSLKRFTARAKGRGNQIEKQTCHITVTLSNMKKIRKGDSVVLLTGR------DK-GKQ GTVTAVLEN----KLV--IEGVNIYKKSVK----PN--PAAGVT-GGMIDKTMPVHISNVA-VVD-GN-------GK--P --SRVGIKL----V--------DGKQR---FLKTTG---ATL--MGQKINPTGFRLA--VT-KNWTSRWYA------NNT D--FAKMLKEDVDVRIYL--KKKLK-----NASVSKVVIERPA-K-NARITIYSSRPGVVIGKKGEDIEVLRRELQKRVH VNIEEIRK---PEVDAQLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGAEIARREWYREGRVPL- -HTLKADIDYATSEAETTYGIIGVKVWVYMSISDPIADMLTRIRNAQAVQKPVVLM-PSSKVKVAIAKVLQDEGYIESFE IKG----E---A----AKPVLHIDLKYY----AG-------R---PVIERIDRVSTPSLRIYKGRHDIPEVMNGLGIAII STPQGVMTDRKARATGVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAVVKGPVPLPTRIERFDILRS PHVNKTSR-DQLEIRTHLRLMDIVDPTEKTVDALMKLDLPAGVDVEIKLRRTLVGRVVSDKMQKTVTVLVERQVKHPVIG KYVGQSKKYHAHDEA--GTYKMGDTVEIAESKPISRTKSWVVTRLVEAS------------------------------- -MTRSA-KKGPFCDA-SLVKKVEVAQA---NKDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVSE-NMVGH KLGEFALTRTFKGHA------A---DK----KVT------KK >BETA_Ralstonia_eutropha_H16 Concatenation of 2 sequences MALVKTKPTSPGRRSMVKVVNKD-LHKG------------AP-HAPLLEKQFQKSGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN-DK-DGIPARVERLEYDPNRSANIALVLFA-DGERRYIIATKGMVAGQPLMNGS-E-AP-IKAGNNLPIR NIPVGTTINNVEMLPGKGSQIARAAGGSAVLLAR--EGLYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRVIGKAGAT -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGR-DPVSP---WGTPAKGYRTR-SNKR-TD-S-MIVQKR --------------------------------MSL---G-LVGRKVGMTRIFT-DDGE---------AIPVTVVEVGDNR VTQIK----TDE----T--DGY--TAVQVTF-------GA--RVTK----------PLAGHLK----------------- ---AG-VEAGEIIREFRI------DAAKAAEL-----QA---GG-SLSV--D-L-FEVGQKIDVQGVTIGKGYAGTIKRY HFAS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTRTVQNLEIAKIDAERK---------------- ----------LLLVKGA-IPGSKNGKVIVT--MELKLLQ-DNGQIG-AGVDASPEVF----GR-DY-NEALVHQIVVAYQ ANARSGNRKQKDREE--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFTQKVNKKMFRAGMRSIYSQLAREG----------------R-INVVDGF----TVD-A------ --PKTKLII--TDSLD--E---NLYLASRNLPHVA-V---------------VEPRQADPLSLVHYKK----VLVTKAAV AQIEARLQEFYKEQV----VPKLIEQFGYKSVMEVPRITKITLNMGLG-EAINDKKIIENAVGDLTKIAGQKPVVTKAKK AIAGFKIRQGYPIGAMVTLRGERMFEFLDRFVTVALPRVRDFRGVSG-RSFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKNDEEAKALLGAFKFPFMSRVG-K--APIALPKGAEVN-V--- -A-A--G-VLSVKGPLGTLSQPI--HS-L--VKVNVEN-DT--LTF----S-P--ADEREAN-ALQGTMRALVANMVKGV TTGFERKLNLVGVGY--RAQLQG-AA--LKLQ--LGFSHDVIHEM-P-E-GVKAETP--T-QTEIIIKG-ADKQKVGQVA AEVRAYR------PPEPY---KGKGVRYSDERVILKETK----------MIQTESRLEVADNTGAREVLCIKVLG-SKRR Y--ASVGDIIKVTVKDAAPR-G-------RVKKGDIYNAVVVRTAKGVRRADGSLIKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMQ-L--NNLKPAAGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLYRRLPK-RG--FTSVTLRDIVDLLVLKQA-GLVGAK---------VIK--AGE-L-T-R-K-VTI- KGLGATAGAKAAIEAAGGQI-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAM--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEDLAREAFRLAAAKLPIATNF-VKKDARLRRARQTRAKI----AEMKVNRLTVFRTNSHIYAQVFSE---C--GTKVL ASASTA-EVEV-RKEL---DGKG-ATAAAATVVGKRIAEK--AKAAG-VETVAFDRAGFRFH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPIERALNVLTFS---------------------------------PKKAAGIVKKVVESAIAN----A- EHNE-GADIDELKVKSIFVDKATSLKRFTARAKGRGNRIEKQTCHITVTLGNMNKIRKGDEVIVLTGK------DK-GKR GTVQAVLGD----KVA--VQGVNIAKKHAR----PN--PMLGTT-GGVVDKVMPLHISNVA-LVD-AN-------GK--P --SRVGIKV----E--------DGRVR---VLKTTG---AVV--MGQKIHPTGFRLA--VS-RNWASRWYA------SNT K--FAGMLKEDIEVRDFL--KKKLK-----NASVGRVVIERPA-R-NARITIYSSRPGVVIGKKGEDIELLKAELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSAGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGFSEAETTYGIIGVKVWVYMSMSDPIADMLTRIRNAQGVQKASVVM-PSSKLKVAIAKVLKDEGYIDDYA VQE----D---G----GKAQLSIGLKYY----AG-------R---PVIERIERVSKPGLRVYKGRSDIPQVMNGLGVAII STPQGLMTDRKARATGVGGEVLCYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVKGPVPLPTRIQRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKVRRTLVGRVVSDKMDKTVTVLVENRVKHPLYG KYVLRSKKYHAHDEA--NQYKEGDKVEIQEGRPLSRTKSWVVSRLVEAA------------------------------- -MTRSA-KKGPFCDA-HLLKKVEVASS---GKDKK----PIKTWSRRSTILPEFIGLTIAVHNGRQHVPVYVTE-NMVGH KLGEFAITRTFKGHA------A---DK----KAK-------R >BETA_Ralstonia_eutropha_JMP134 Concatenation of 2 sequences MALVKTKPTSPGRRSMVKVVNKD-LHKG------------AP-HAPLLEKQFQKSGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN-DK-DGIAAKVERLEYDPNRSANIALVLFA-DGERRYIIATKGMVAGQALLNGA-E-AP-IKAGNNLPIR NIPVGTTINNVEILPGKGAQVARAAGGSAVLLAR--EGLYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRVIGKAGAT -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGR-DPVSP---WGTPAKGYRTR-SNKR-TD-S-MIVQKR --------------------------------MSL---G-LVGRKVGMTRIFT-DDGD---------SIPVTVVEVGDNR VTQIK----TDE----T--DGY--TAVQVTF-------GA--RVTK----------PLAGHLK----------------- ---AG-VEAGEIIREFRI------DAAKAAEL-----QT---GG-SLSV--D-L-FEVGQKIDVQGVTIGKGYAGTIKRY HFAS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDVTRTVQNLEIAKIDAERK---------------- ----------LLLVKGA-IPGSKNGKVIVT--MELKLLQ-DNGQVG-AGVAASPEVF----GR-DY-NEALVHQIVVAYQ ANARSGNRKQKDREE--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMFRAGMRSIYSQLAREG----------------R-INVVDGF----TVD-A------ --PKTKLII--TDSLD--E---NLYLASRNLPHVA-V---------------VEPRQADPLSLVHYKK----VLVTKAAV AQIEARLQEFYKEKV----VPKLIEQFGYKSVMEVPRITKITLNMGLG-EAINDKKIIENAVGDLTKIAGQKPVVTKAKK AIAGFKIRQGYPIGAMVTLRGERMFEFLDRFVTVALPRVRDFRGVSG-RSFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKNDEEAKALLGAFKFPFMSRVG-K--APIALPKGAEVN-V--- -A-A--G-VLSVKGPLGTLSQPI--HS-L--VKVNVEN-DT--LTF----A-P--ADEREAN-ALQGTMRALAANMVKGV TTGFERKLNLVGVGY--RAQLQG-AA--LKLQ--LGFSHDVIHEM-P-E-GVKAETP--T-QTEIIIKG-ADKQKVGQVA AEVRAYR------PPEPY---KGKGVRYSDERVILKETK----------MIQTESRLEVADNTGAREVLCIKVLG-SKRR Y--ASVGDIIKVTVKDAAPR-G-------RVKKGDIYNAVVVRTAKGVRRADGSLVKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMQ-L--NNLKPAAGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLYRRLPK-RG--FTSVSLRDIVDLLVLKQA-GLVSAK---------VIK--AGE-L-T-R-K-VTI- KGLGATAGAKAAIEAAGGQI-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAM--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEDLAREAFRLAAAKLPIATNF-VKKDARLRRARQTRAKI----AEMKVNRLTVFRTNSHIYAQVFSE---C--GTKVL ASASTA-EVEV-RKEL---DGKG-ATAAAATVVGKRIAEK--AKAAG-VETVAFDRAGFRFH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPIERALNVLTFS---------------------------------PKKAAGIVKKVVESAIAN----A- EHNE-GADIDELKVKSIFVDKATSLKRFTARAKGRGNRIEKQTCHITVTLGNMNKIRKGDEVIVLTGK------DK-GKR GTVQAVLGD----KVA--VEGVNVAKKHAR----PN--PMLGTT-GGVVDKVMPLHISNVA-LVD-AN-------GK--P --SRVGIKV----E--------DGRVR---VLKTTG---AVV--MGQKIHPTGFRLA--VS-RNWASRWYA------N-N T-KFAGMLKEDIEVRDFL--KKKLK-----NASVGRVVIERPA-R-NARITIYSSRPGVVIGKKGEDIELLKAELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGFSEAETTYGIIGVKVWVYMSMSDPIADMLTRIRNAQGVQKASVVM-PSSKLKVAIAKVLKDEGYIDDYA VQE----D---G----GKAQLSIGLKYY----AG-------R---PVIERIERVSKPGLRVYKGRSDIPQVMNGLGVAII STPQGLMTDRKARATGVGGEVLCYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVKGPVPLPTRIQRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKVRRTLVGRVVSDKMDKTVTVLVENRVKHPLYG KYVLRSKKYHAHDEA--NQYKEGDKVEIQEGRPLSRTKSWVVSRLVEAA------------------------------- -MTRSA-KKGPFCDA-HLLKKVEAAVG---GKDKK----PIKTWSRRSTIMPEFIGLTIAVHNGRQHVPVYVTE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------R >BETA_Ralstonia_metallidurans_CH34 Concatenation of 2 sequences MALVKTKPTSPGRRSMVKVVNKD-LHKG------------AP-HAPLLEKQFQKSGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN-DK-DGIAAKVERLEYDPNRSANIALVLFA-DGERRYIIATKGMVAGQALMNGS-E-AP-IKAGNNLPIR NIPVGTTINNVEILPGKGAQVARAAGGSAVLLAR--EGLYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRVIGKAGAT -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPAKGYRTR-SNKR-TD-S-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-DDGD---------SIPVTVVEVGDNR VTQIK----TDE----T--DGY--TAVQVTF-------GS--RVTK----------PLAGHLK----------------- ---AG-VEAGEVIKEFRI------DAAKAAEL-----QA---GS-SLSV--D-L-FQVGQKIDVQGVSIGKGYAGTIKRH HFAS-GRATHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDATRTVQNLEIAKIDAERK---------------- ----------LLLVKGA-IPGSKGGKVIVT--MELKLLQ-DNGQIG-AGVAASAEVF----GR-DY-NEALVHQIVVAYQ ANARSGNRKQKDREE--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMFRAGMRSIYSQLAREG----------------R-INVVDGF----AVD-A------ --PKTKLII--TDNLD--E---NLYLASRNLPNVA-V---------------VEPRHADPLSLVHYKK----VLVTKAAV AQIEARLQEFYKEQV----VPALMKQFGYKSVMEVPRFTKITLNMGLG-EAINDKKVIELAVGDLTKIAGQKPVVTKAKK AIAGFKIRQGYPIGAMVTLRGERMFEFLDRFVTVALPRVRDFRGVSG-KSFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKNDEEAKALLNAFKFPFMSRVG-K--APIALPKGAEVN-V--- -A-A--G-VLSVKGPLGTLSQPI--HS-L--VKVNVAE-GT--LTF----E-P--ADEREAN-ALQGTMRALAANMVKGV TTGFERKLQLVGVGY--RAQLQG-AA--LKLQ--LGFSHDVIHEM-P-E-GVKAETP--T-QTEIIIKG-ADKQKVGQVA AEVRAYR------PPEPY---KGKGVRYADERVILKETK----------MIQTESRLEVADNTGAREVLCIKVLG-SKRR Y--ASVGDIIKVTVKDAAPR-G-------RVKKGDIYNAVVVRTAKGVRRADGSLVKFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMQ-L--NNLKPADGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLYRRLPK-RG--FTSVTLRDIVDLLVLKQA-GLVGAK---------VIK--AGE-L-S-R-K-VTI- KGLGATAGAKAAIEAAGGQI-K---EQK--GRN---TGKA-TRGNAVSFG----------EFGLKAM--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VSEELAREAFRLAAAKLPIATNF-VKKDARLRRARQTRAKI----AELKVNRLTVFRTNSHIYAQVYSP---C--GTQVL ASASTA-EAEV-RKEL---NGNG-ATVAAATVVGKRVAEK--AKAAG-VETVAFDRAGFRFH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPIERALNILAFS---------------------------------PKKAAGIVKKVVESAIAN----A- EHNE-GADIDELKVKSIFVDKATSLKRFTARAKGRGNRIEKQTCHITVTLGNMNKIRKGDEVIVLTGK------DK-GKR GTVQAVQGD----KVV--VEGVNVAKKHAR----PN--PMLGTT-GGVVDKLMPLHISNVA-LVD-AN-------GK--P --SRVGIKV----E--------DGRVR---VLKTTG---AVL--MGQKIHPTGFRLA--VS-RNWASRWYA------NNT K--FAGMLKEDIEVREFL--KKKLK-----NASVGRVVIERPA-R-NARITIYSSRPGVVIGKKGEDIELLKAELQRRVH VNIEEIRK---PETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGFSEAETTYGIIGVKVWVYMSMSDPIADMLTRIRNAQGVQKASVVM-PSSKLKAAIAKVLKDEGYVEDFS VQE----E---G----GKAQLTIGLKYY----AG-------R---PVIERIERVSKPGLRVYKGRSDIPHVMNGLGVAII STPQGLMTDRKARATGVGGEVLCYVAMQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVKGPVPLPTRIQRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKVRRTLVGRVVSDKMDKTVTVLIENRVKHPLYG KYVLRSKKYHAHDEA--NQYKEGDKVEIQETRPLSRTKSWVVSRLVEAA------------------------------- -MTRSA-KKGPFCDG-HLLKKVEAAVG---GKDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVTE-NMVGH KLGEFAITRTFKGHA------A---DK----KAK------R- >BETA_Ralstonia_pickettii_12J Concatenation of 2 sequences MALVKTKPTSPGRRSMVKVVNPD-LHKG------------AP-HAPLLEKQIQKSGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN-DK-DGIPAKIERLEYDPNRSANIALVLFA-DGERRYIIAPKGAVVGQAIANGS-E-AP-IKAGNNLPIR NIPVGTTIHCVEILPGKGAQVARSAGTSAVLLAR--EGIYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRQIGKAGAT -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-A--AGR-DPVSP---WGTPTKGYRTR-RNKR-TD-S-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFT-DDGD---------SIPVTVLEVGDNR VTQIK----TDE----T--DGY--TAVQVTF-------GT--RVTK----------PLAGHLK----------------- ---AG-VEAGEVIKEFRV------DAARAAEF-----QP---GA-NISV--D-L-FEVGQKIDVQGVTIGKGYAGTIKRY NFSS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDVTRTVQNLEIAKIDAERK---------------- ----------LLLVKGA-IPGAKGGQVIVT--MELKLLQ-DNGQLG-AGVAASPEVF----GR-DY-NEALVHQVVVAYQ ANARSGNRKQKDREE--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMYRAGMRSIYSQLAREG----------------R-INVVDSL----SVD-A------ --PKTKLVI--TDNLD--E---NLFLASRNLAHVL-V---------------VEPRHADPLSLVHYKK----VLVTKAAV AQIEARLQEFYKEKV----VPELIKQFGYKSVMEVPRITKITLNMGLG-EAINDKKVIEHATGDLIKIAGQKPIVTKARK AIAGFKIRQGYPIGTMVTLRGQRMYEFLDRFITVSLPRVRDFRGVSG-KAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKNDEEAKALLNAFKFPFMSRVG-K--APIALPKGAEVN-F--- -A-G--G-LLTVKGPLGTLTQPI--HS-L--VKVNTDN-GT--ITF----A-P--ADEREAN-ALQGTMRALTANMVKGV TTGFERKLNLVGVGY--RASVQG-TA--LKLQ--LGFSHDVIHEM-P-E-GVKAETP--T-QTEIIIKG-SDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYADERVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASVGDIIKVSVKDAAPR-G-------RVKKGDIYNAVVVRTAKGVRRPDGSLIKFDGNAAVLLN-TKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMQ-L--NNLKPAAGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLHRRLPK-RG--FTSVRLGDLVDLLSLKQA-GLVGAK---------VIL--SGE-I-D-K-K-VTL- KGIGATAGAKAAIEAAGGSL-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAM--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VGEELAREAFRLAAAKLPIATSF-VKNDSRLRRARQTRLKI----AELSVARLAVHRTNLHIYAQVFSE---D--GTKVL ASASTA-EAEV-RKEL---NGNG-GNTAAATLVGKRIAEK--AKAAG-IEAVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLSIERALNVLTFS---------------------------------PKKAAGIVKKVVESAIAN----A- EHNE-GADIDELKVKSIYIDKATSLKRFTARAKGRGNRIEKQTCHITVTLGNMNKIRKGDRVIVRTGK------DK-GKQ GTVLAVLAE----HVT--VEGVNVAKKHVR----PN--PMLGTT-GGVVDKIMPIHISNVA-LVD-AN-------GK--P --SRVGIKV----E--------GGKTR---VLKTTG---AAV--MGQKIHPTGFRLA--VS-RNWASRWYA------SNT Q--FAGMLKEDIEVREFL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIELLKAELQRRVH VNIEEIRK---PEVDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGFSEAETTYGIIGVKVWVYMSMSDPIADMLTRIRNAQAVEKASVVM-PSSKLKVAIAKVLKDEGYIDEFA VTE----Q---G----GKSTLTIGLKYY----AG-------R---PVIERLERVSKPGLRVYKGRNEIPQVMNGLGVAII STPQGLMTDRRARATGVGGEVICYVAMQNQKIRIRLKAFDYRLIDQSAAEIVETAKRTGAIVKGPVPLPTRIQRFDVLRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSNKMDKTVTVLIENRVKHPLYG KYVVRSKKYHAHDEA--NQYNEGDKVEITESRPLSRTKSWVVSRLLEAA------------------------------- -MTRSV-KKGPFIDA-HLLKKVEAAVQ---TKDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVTE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK-------R >BETA_Ralstonia_solanacearum_GMI1000 Concatenation of 2 sequences MALVKTKPTSPGRRSMVKVVNPD-LHKG------------AP-HAPLLEKQFQKSGRNNNGHITTRH-KGGGHKHH---- YRIVDFK-RN-DK-DGIPAKIERLEYDPNRSANIALVLFA-DGERRYIIAPKGAVVGQAVANGP-E-AP-IKAGNNLPIR NIPVGTTIHCVEILPGKGAQIARSAGTSAVLLAR--EGIYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRQIGKAGAT -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGKT-A--AGRD-PVSP---WGTPTKGYRTR-SNKR-TT-S-MIVQRR --------------------------------MSL---G-LVGRKVGMTRVFT-DDGD---------SIPVTVLEVGGNR VTQIK----TDE----T--DGY--TAVQVTF-------GT--RVTK----------PLAGHLK----------------- ---AG-VEAGEIIVEFRI------DATKAAEL-----KL---GD-TIDV--D-L-FSVDQKIDVQGTTIGKGYAGTIKRY HFSS-GRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHMGDVTRTVQNLVIVRIDAERK---------------- ----------LLLVKGA-VPGAKSGFVVVS--MELKLLQ-ADGQLG-TGVSASPEVF----GR-DY-NEALVHQIVVAYQ ANARSGNRKQKDREE--------VK-HTTKKPW---------RQKGTGRAR--------AGM---SS-SP----LW---- RGGGRIFPNS-PEENFSQKVNKKMYRAGMRSIYSQLAREG----------------R-INVVDSL----SVD-A------ --PKTKLVI--TDNLD--E---NLFLASRNLAHVL-V---------------VEPRHADPLSLVHYKK----VLVTKAAV AQIEARLQEFYKEKV----VAELIKQFGYKSVMEVPRITKITLNMGLG-EAVNDKKVIEHATGDLTKIAGQKPVVTKARK AIAGFKIRQGYPIGTMVTLRGQRMYEFLDRFITVSLPRVRDFRGVSG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKI DALRGLNISITTT-----------------------AKSDEEAKALLAAFKFPFMSRVG-K--APIALPKGAEVN-F--- -A-G--G-LLTVKGPLGTLTQAI--HN-L--VKVVIDN-GT--ITF----S-P--ADEREAN-ALQGTMRALVANMVKGV TTGFERKLTLVGVGY--RASLQG-AA--LKLQ--LGFSHDVIHEM-P-E-GVKAETP--T-QTEIIIKG-SDKQKVGQVA AEVRGYR------PPEPY---KGKGVRYANERVILKETK----------MIQTESRLEVADNTGAREVMCIKVLG-SKRR Y--ASVGDIIKVSVKDAAPR-G-------RVKKGDIYNAVVVRTAKGVRRPDGSLIKFDGNAAVLLN-TKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMQ-L--NNLKPAAGS-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLHRRLPK-RG--FTSVRLGDLIDLLTLKQA-GLVGAK---------VIL--SGS-I-D-K-K-VTL- KGLGATAGAKAAIEAAGGSL-K---EQK--GRN---TGIA-TRGNAVSFG----------EFGLKAM--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYYVAEIQP-GKMLYEM--DG-- VGEELAREAFRLAAAKLPIATSF-VKNDSRLRRARQTRLKI----AELNVARLAVHRTNLHIYAQVFSE---D--GTKVL ASASTA-EAEV-RKEL---NGNG-GNTAAATLVGKRIAEK--AKAAG-IEAVAFDRSGFRYH--GRVKALADAAREAGLK F--------------------------------------------------------------ME-VKAIHRGARISAQK TRLVADQIRGLPIERALNVLAFS---------------------------------PKKAAVIVKKVVESAIAN----A- EHNE-GADIDELKVKSIYIDKATSLKRFTARAKGRGNRIEKQTCHITVTLGNMNKIRKGDRVIVRTGK------DK-GKQ GTVLAVLGE----HVT--VEGVNVAKKHVR----PN--PMLGTT-GGVVDKVMPIHISNVA-LVD-AN-------GK--P --SRVGIKV----E--------NGKTR---VLKTTG---AAV--MGQKIHPTGFRLA--VS-RNWASRWYA------S-N T-QFAGMLKEDIEVREFL--KKKLK-----NASVGRVVIERPA-K-NARITIYSSRPGVVIGKKGEDIELLKAELQRRVH VNIEEIRK---PEVDAQLIADSITQQLERRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARTEWYREGRVPL- -HTLRADIDYGFSEAETTYGIIGVKVWVYMSMSDPIADMLTRIRNAQAVEKASVVM-PSSKLKVAIAKVLKDEGYIDDFA VTE----Q---G----GKASLTIGLKYY----AG-------R---PVIERLERVSKPGLRVYKGRNEIPQVMNGLGVAII STPQGLMTDRRARATGVGGEVICYVAQQNQKIRIRLKAFDYRLIDQSAAEIVETAKRTGAIVKGPVPLPTRIQRFDVLRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGRVVSSKMDKTVTVLVENRVKHPLYG KYVVRSKKYHAHDEA--NQYKEGDRVEIVESRPISRTKAWVVSRLVEAA------------------------------- -MTRSA-KKGPFIDA-HLLKKVEAAAG---GKDKK----PIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVTE-NMVGH KLGEFALTRTFKGHA------A---DK----KAK------R- >BETA_Rhodoferax_ferrireducens_T118 Concatenation of 2 sequences MAVIKMKPTSPGRRGVVKISRDH-LYKG------------EP-FAPLLEPQFQHAGRNNNGHITTRH-KGGGHKHH---- YRVVDFL-RT--K-DGIPAKVERIEYDPNRSAHIALVCYA-DGERRYIIAPRGLEVGASIMSGA-E-AP-IRVGNTLPIR NIPVGSIVHCIELQIGKGAQIVRSAGTSATLLAR--EGIYAQVRMRSGEVRKIHIECRATLGQVANEEHSLRRLGKAGAK -RWK-----GIR-P-TVRGVVMNPVDHPHGGGEGKT-G--EGR-HPVDP---WGNLTKGYRTR-NNKR-TQ-V-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DEGD---------SIPVTVVDVSNNR VTQVK----TQE----N--DGY--VALQVTF-------GA--RVTK----------PAAGHLK----------------- ---AG-VEAGEIIREFRL------TADVAAQY-----KA---GA-TVPV-TA-V-FAVGQKVDVQGTTIGKGFAGTIKRH HMKS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDDTVTTQNLDVIRIDEARQ---------------- ----------LLMIKGA-VPGSAGGFVTVR--MQLELLN-DQGLAT-AKYEAPETVF----GR-AY-NEDLVHQIVVAFQ ANARQGTRAQKDREQ--------VK-HSTKKPF---------KQKGTGRAR--------AGM---TS-SP----LW---- RGGGRIFPNM-PDENFTQKINKKMYRAGMASILSQLAREG----------------R-LAVVDSM----KVD-S------ --PKTKLVI--ADEVD--E---NLYLASRNLVNVL-V---------------VEPRYADPVSLVHYRK----VIVTKAAM EKLQARLQQHFREKL----APELMAKFGYTSPMQVPRLTKITLNMGVS-EAVADKKVMDHAVSDLGKIAGQKPVVTMSKK AIAGFKIRENQAIGCMVTLRGVQMFEFLDRFVTVALPRVRDFRGISG-RAFDGRGNYNIGVKEQIIFPEIE-----YDKV DALRGLNISITTT-----------------------AKTDEECKALLTGFRFPFMSRIG-K--MPVAVPAGVDVL-V--- -K-D--D-QISVKGAGGSLFLTQ--NA-L--VKVSSDA-GA--LSF----Q-P-ANDSREAN-AMSGTMRQLVNNMVVGV TKGFEKKLNLVGVGY--KAQAQG-AK--LNLT--VGYSHPVNKDM-P-A-GITVATP--T-PTEIVIKG-ADRQRVGQVA AEIRAIR------PPEPY---KGKGIRYSDEKITIKETK----------MIQVESRLEVADNTGAKSVLCIKVLG-SKRR Y--ASVGDVIKVSIKEAAPR-G-------RVKKGEIYSAVVVRTAKGIRRSDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLME-L--NGIKPADGA-KHYKRRVG-RGIGSGI-GKTAGRGHKGQKSRAGGY-H--- -KVGF-E-GGQMPMQRRLPK-RG--FKSVTLSALVDLVTLKQA-GLVGVK---------VIM--TGK-I-S-K-A-VKL- TGIGATAAAKVAIEAAGGSL-K---EQK--GRN---TGIA-TRGSSVAFG----------DFGLKCI--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISQKPAEVRMGNGK---------GNPEYYVAEIQP-GKIVFEI--VG-- VPEELAREAFRLAAAKLPLRTTF-VKKEQRLRRARQTRIRI----ATQGVARLTVNRTNLHIYASVISG---D--GVKVL ASASTA-EAEV-RKAL-GGSGKG-GNVAAAQAIGKRLAEK--AKAVG-VEKVAFDRAGFAYH--GRVKALADAAREAGLQ F--------------------------------------------------------------ME-TRATLRGVRLSVDK GRLVADLIRGKKVDQALNILQFT---------------------------------QKKAAVIIKKVLESAIAN----A- EHND-GADIDELRVKTIFVEQGASLRRFTARAKGRGNQIRKPTCHVYVTVGNMNKIRKGDDIIVLTGR------DK-GKR GKIALRKDDSY---VL--VEGINVVKKHTK----PN--PLKGTV-GGIVEKSMPIHQSNVA-IFNVAT-------GK--A --DRVGIKL---AA--------DGRVR---VYKSSG---EEI--MGQKIHPTGFRLS--IS-RNWASRWYA------NDR D--FAGMLAEDIKVREYL--KAKLK-----NASVSRVLIERPA-K-NARITIFSARPGVVIGKKGEDIENLKRELSRQVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GALGIKIMSSGRLNGIEIARCEWYREGRVPL- -HTLRADIDYGTSEAQTTYGIIGVKVWVYMSMSDPIADLLTRIRNAQMVAKTTVSV-PSSKVKVAIAQVLTEEGYIDSFK VNA----N---D----GKPELEIVLKYY----AG-------R---PVIERIERVSRPGLRVYRGSDAIPQVQNGLGVAIV TTPKGVMTDRKARATGVGGEVLCYVAATKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRFKRFDILRS PHVNKTSR-DQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLVGKVVSDKRAKTVTVLIERRVKHELYG KIVGKSSKYHAHDET--GEYKLGDIIEITESRPISKTKNWVATRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLVAKADKAVA---TKDKK----PIKTWSRRSMVLPDFIGLTIAVHNGKQHVPVYITD-QMVGH KLGEFALTRTFKGHP------A---DK----KVQ------KK >BETA_Thauera_sp_MZ1T Concatenation of 2 sequences MAIVKLKPTSAGRRAQVKVVNPD-LYKG------------RP-VDALIEKQTKNAGRNNYGRVTMRH-QGGGHKQH---- YRLVDFR-R--NK-DGIPAKVERIEYDPNRSAHIALLCYA-DGERRYIIAPRGVEVGQQLISGA-E-AP-IKAGNALPIR NIPVGSTIHCIEMVPGKGAQLARAAGTSVQLLAR--EGSYAQLRLRSGEIRRVHVECRATIGEVGNGEHGLRKIGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----GEAREPVSP---WGTPAKGYRTR-SNKR-TD-G-MIVQRR --------------------------------MSL---G-LVGRKVGMTRIFA-EDGK---------TIPVTVLDVSDNR VSQIK----TID----T--DGY--AAVQIAY-------GK--RITK----------PVAGHLK----------------- ---AG-VEPCRGIKEFRV------EAEQAGSM-----NA---GD-AVGA--D-L-FQVGQKVDVTGVTIGKGFSGPIKRH NFSS-NRASHGNSISHNS-PGSIGMA-QDPG-RVFPGKRMAGQYGNVQRTTQGLEIVRVDVERQ---------------- ----------LLLVKGA-VPGAKGGDVVVR--MELKLLN-DQGQAA-STLEASDVLF----GR-DY-NEALVHQVVTAYL ANARSGNRKQKGRSE--------IA-KSTRKPF---------RQKGTGNAR--------AGM---AS-SP----LW---- RGGGKIFPSS-PDENFSQKVNRKMYRAGVAAILSQLARED----------------R-LAVVENF----SVE-A------ --PKTRLVI--TDEID--E---NLFLSSRNLHQVL-V---------------LEVSEADPVSLVRFPK----VLVTKGAL AKMEARLQQVYKDEV----APALQQQFGYKSVMEVPRITKITLNMGVG-EAVGDKKILEHAIGDMTKIAGQKPVSTKARK SIAGFKIRDGYPIGCMVTLRGPRMFEFLDRLITIALPRVRDFRGIAA-KGFDGRGNYNLGVKEQIIFPEIE-----YDKI DALRGMNISITTT-----------------------AKTDEEARALLGAFKFPFMSRVA-K--NPVAIPQGVEVM-I--- -S-D--A-EIAVKGPLGTLRQPL--SG-E--VSVVREG-DA--VVC----K-A--REGENAR-AMSGTVRALVNNMVTGV TKGFERKLTLVGVGY--RAQAQG-DK--LNLS--LGFSHPVVHQM-P-E-GVKVETP--T-QTEIVIRG-SDKQKVGQVA AEVRAYR------APEPY---KGKGVRYSDEVVVLKETK----------MIQMQSKLDVADNSGARSVMCIKVLG-SKRR Y--AGVGDIIKVTVKDAAPR-G-------RAKKGDVYNAVVVRTAKGVRRPDGSLIKFDSNAAVLLN-NKLE-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMR-L--NSIKPGEGS-KKEARRVG-RGIGSGL-GKTCGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPLQRRLPK-RG--FVSVRLSELVDLLTLKQA-GVIAAK---------VVL--SGS-I-S-R-K-VVL- RGVGATQGAKAAIEAAGGSV-K---EQK--GRN---TGVA-TRGAKVSFG----------EYGLKAI--GRGRLTARQIE SARRAMTRHI------KRGGRIWIRIFPDKPISKKPAEVRMGNGK---------GNPEYWVAEIQP-GKVLYEM--DG-- VDEALAREAFRLAAAKLPIETVF-VKKETRLRRARKTRAKI----AELKAVRLTVFRSNCHIYAQIISG---C--GSRVL AAASTV-EPDV-RAQV----ANG-GNKAAAEAVGKLIAER--AKAAG-VEQVSFDRSGFLYH--GRVKALAEAAREGGLK F--------------------------------------------------------------ME-TKAILRGVRLSAQK GRLVADLVRGMPVGRALDTLAFS---------------------------------PKKGAKIIRKVLESAIAN----A- EHND-GADIDALKVKTIHVEEGMTLKRFTARAKGRGNRILKPTCHVYLTVGEMNKIRKGDEVLVLTGK------DR-GRR GTVLRRVDDER---VV--VEGVNRVKKHVR----PN--PLKGEV-GGIVEKEMPIHVSNVA-LFNPAT-------QK--G --DRVGIKT---LE--------DGKVR---FFKSNG---ELV--MGQKIHPTGFRLA--VT-RDWGSRWFA------NSK D--YAGMLHEDLKVRDYL--KKRLA-----HASVGRVVIERPA-K-NARVTLYSARPGVVIGKKGEDIEALKRDLQKIVH VNIEEVRK---PELDAKLIADSIAQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGAEIARTEWYREGRVPL- -HTLRANIDYGVSEAKTTYGVIGIKVWVFMSMSDPIADMLTRIRNGQQAQKASVSM-PSSKLKVAIAKVLQDEGYIDGFA VRD----E---A----GKASLDVTLKYY----AG-------R---PVIERLERVSRPGLRIYKGSDDLPRVMNGLGVAIV STPRGVMTDRSARANRVGGEVICLVAMQNQKIRIRLKAFDYRLIDQSALEIVDTAKRTGAVVRGPVPLPTRIERFDLLRS PHVNKASR-DQMEIRTHQRLMDIIDPTDKTVDALMKLDLPAGVDVEIKLRRALVGRVVSDKMQKTVTVLVERRVKHPLYG KIITRSAKYHAHVED--GVAAQGDLVEIEECRPISRTKTWRVAKVLEKA------------------------------- -MARSI-KKGPFIDA-HLLKKVDAART---SNDKR----PIKTWSRRSTILPDFIGLTIAVHNGKQHIPVFVTE-NMVGH KLGEFALTRTFKGHA------A---SK----KAK-------R >BETA_Thiobacillus_denitrificans_ATCC_25259 Concatenation of 2 sequences MALIKVKPTSAGRRAVVKVVTPG-LHKG------------KP-LAALLEPKKRGSGRNNNGHITVRH-KGGGHKQH---- YRVVDFR-R--NK-DGIPAKVERIEYDPNRSAHLALLCYA-DGERRYIIAPRGIAVGAQLVNGV-E-AP-IKAGNCLPLR SIPVGSTVHCVEMMPGKGAQIARSAGTSVQLLAR--EGSYAQLRLRSGEIRKVHVDCRATLGECGNEEHSLRSIGKAGAS -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGRT----AAGRHPVSP---WGTPTKGYRTR-SNKRTSN---MIVRRR --------------------------------MSI---G-LVGRKVGMTRIFT-ENGA---------SVPVTVLEMSNNR VTQVR----TPE----N--DGY--SAVQVAY-------GS--RVNK----------SEAGHYK----------------- ---AG-VDAGELLREFRV------AADVAAQY-----QP---GA-AVSV--E-V-FQAGQKVDVTGVTQGKGFAGTIKRH NFKS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMSGHMGAVSCTKQNLEVVRVDAERG---------------- ----------LVLLKGA-VPGSKGGHVVVR--MDLTVIN-DRGEQV-ASVAASDETF----GR-DY-NEALVHQVVTAFQ ANARSGNRAQQTRAE--------VS-ASTHKPW---------RQKGTGRAR--------SGR---AS-SP----IW---- RGGGVTFPNK-PNENFTHKVNRKMYRAGLAAILSQLAREG----------------K-LKVVESL----GIE-S------ --PKTKMII--ADAID--D---NLWLSSRNLPNVY-V---------------VEPHQADPWSLVKFGN----VLITKAAI KQFEARFQEFYRETV----VPKLIEQFGYKSVMEVPRIQKITLNMGVG-EAVADKKVMDHAVADMQKIAGQKPVVTKSKK SIAGFKIRENYPVGCMVTLRRGQMYEFLDRLVTVALPRVRDFRGVSG-KSFDGRGNYNMGIKEQIIFPEIE-----YDKI DALRGMNITITTT-----------------------AKTDDEARALLAAFSFPFMSRVA-N--NPITVPKGVEVT-L--- ---G--D-GIAVKGPLGSMSQPM--SS-D--VTVALND-GV--LTF----A-P-VGSSIQAN-AMAGTLRALVNNMVQGV SKGFERKLTLVGVGY--RAQAQG-DA--LNLS--LGFSHPVVHKM-P-A-GIKVETP--T-QTEIVIKG-IDRQAVGQVA ADVRAYR------PPEPY---KGKGVRYSDEVVIKKETK----------MIQMQSVLDVADNTGARSVMCIKVLG-SHRR Y--AGVGDIIKVSIKDAAPR-G-------RVKKGDVYNAVVVRTAKGVRRPDGSLVRFDGNAAVLLN-NKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLME-L--NNIKPADGA-KKDKRRVG-RGIGSGL-GKTAGRGHKGQKSRAGGF-H--- -KVGF-E-GGQMPMHRRLPK-RG--FVSVRLSDLIDLLVLKQA-GVVSAK---------VYL--AGE-L-G-K-A-IKL- SGVAVTKGARAAIEAAGGSV-K---EQK--GRN---TGLA-TRGADVSFG----------DFGLKAV--GRGRLTARQIE AARRAMTRHI------KRGGRIWIRIFPDKPISRKPAEVRMGNGK---------GAPEYYVAEIQP-GKVLYEM--DG-- VNEQLAREAFRLAAAKLPIATTF-VTKQSRIRRARKTRAKI----AAVKAIRLAIHRTNSHIYAQIISA---D--GGTVM ASASSN-DKDL-RGQL----ANG-GTTAAAAAVGKRLAEK--AKGLG-IEKVAFDRAGFKFH--GRVKALAEAAREGGLA F--------------------------------------------------------------ME-VSAILRGTRLSAQK GRLVADQIRGLRVEKALNILAFS---------------------------------PKKGAGIIKKVLESAIAN----A- EHNE-GADIDALKVKTIYVDQGSVLKRFTARAKGRGNRISKPTCHITVTVGDMARIRKSDQVIILAGK------DK-GKR GTVLRVLDDGH---LV--VEGVNRVKKHQK----PN--PMRNIQ-GGIVEKEMPIDASNVA-LFNPAT-------QK--A --DRVGSKV---LE--------DGKVR---VFKSNG---EMV--MGQKIHPIGFRLG--VQ-RIWTAKWYG------SNR N--FSDTLLEDIKVRDYL--KKKLS-----HASVSKVLIERPA-K-NARITIFSGRPGVVIGKKGEDIEVLRGELARLVH VNIEEVRK---PETDAQIVADGIAQQLEKRVMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGAEIARTEWYREGRVPL- -HTLRAEIDYGFAEAKTTYGIIGIKVWVYMSMSDPIADMLTRIRNAQQVEKMAVSM-PSSKVKVAIAKVLKDEGYIEDFA VRG----E---A----GKPELELQLKYY----AG-------R---PVIEHIERVSKPGLRIYKGAGDLPRVKNGLGVAIV STSSGVMTDRHARAKGVGGEVLCFVAMQNQKIRIRLKAFDYKLIDQSALEIVETAKRTGAVVKGPVPLPTSIERFDVLRS PHVNKSSR-DQFEIRTHRRLMDIMDPTDKTVDALMKLDLPAGVDVEIKLVRTLTGRVVSDKMNKTVTVLVERRVKHPVIG KVIRMSKKYHAHDEN--NECHEGDTVQIEESRKLSRTKAWTVSKLVERA------------------------------- -MARSI-KKGPFVDG-HLLKKVEAVRG---SNDKR----PIKTWSRRSTVLPDFIGLTIAVHNGRQHVPVFVTE-NMVGH KLGEFSLTRTFKGHV------A---DK----KAK-------K >BETA_Verminephrobacter_eiseniae_EF01-2 Concatenation of 2 sequences MAVIKMKPTSPGRRAVVKVTREH-LHKG------------QP-HAPLLEPQFQKAGRNNNGHITTRH-KGGGHKHH---- YRVVDFK-RN--K-DGIAAKVERIEYDPNRTAHIALVCYA-DGERRYIIAPRNLEVGATLLSGA-E-AP-IRAGNTLPIR NIPVGSTIHCIELKPGAGAQIARSAGASATLLAR--EGTYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRQLGKAGVK -RWM-----GIR-P-TVRGVAMNPVDHPHGGGEGRT-G--EGR-HAVDP---WGNLTKGYRTR-NNKR-TQ-S-MIVSRR --------------------------------NSL---G-LLGRKVGMMRLFT-DDGD---------AVPVTVVDVSDNR VTQVK----TQE----N--DGY--VALQVTF-------GA--RVSK----------PEAGHLK----------------- ---AG-VQAGEIIQEFRV------SADTAAQY-----QA---GA-SVAI-TS-V-FSVGQKVDVQGTSIGKGYAGTIKRH NMRS-QRASHGNSRSHNV-PGSIGMA-QDPG-RVFPGKRMTGHLGDATRTTQNLDLIRIDEARQ---------------- ----------LLLIKGA-IPGSKGGFVTVR--MQLELLN-DQGQGA-SRLDVPETVF----GR-EY-NEALVHQIVVAYQ ANARQGTRAQKDRGQ--------VR-HSTRKPF---------KQKGTGNAR--------AGM---TS-SP----LW---- RGGGRIFPNM-PDENFTHKINKKMYRAGMSAIFSQLAREG----------------R-LAVVESI----KLD-S------ --PKTRMVI--ADEVD--E---NLYLAARNLVNVL-V---------------VEPRYADPVSLVRFKK----VLVTKGAI DKLQARLQAIYRDKL----VPELIRQFGYSSPMQVPRLSKITLNMGVS-EAVSDKKVMDSAVADLTRIAGQKPVVTKAKK AIAGFKIREGQAIGCMVTLRGVQMYEFLDRFVTVALPRVRDFRGISG-RSFDGRGNYNVGVKEQIIFPEIE-----YDKV DALRGLNVSITTT-----------------------ARTDEEAKALLAGFRFPFMSRVA-K--MPVTIPAGVDVS-V--- -K-D--D-QIAVKGAGGTLSLAQ--NV-L--VKVTSSD-GK--LRF----E-P-ANESRQAN-AMSGTLRQLVNNMVLGV SKGFEKKLSLVGVGY--KAAAAG-AK--LNLV--VGYSHPVNIDM-P-A-GITVTTP--T-PTEVVVKG-ADRQRVGQIA AEIRAVR------PPEPY---KGKGIRYADEKITIKETK----------MIQTESRLEVADNTGAKSVLCIKVLG-SKRR Y--ASVGDIIKVSVKEAAPR-G-------RVKKGEIYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLN-AKLE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMQ-L--NSIKPAAGA-KHAKRRVG-RGIGSGL-GKTAGRGHKGQKSRAGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FKSVTLTTLVDVLALKQA-GLVGVK---------VIK--SGA-L-N-R-A-VKL- SGVGVTAGAKAAIEAAGGSV-K---EQK--GRN---TGVA-TRGATVAFG----------DFGLKCT--DRGRLTARQIE AARRAISRHV------KRGGRIWIRVFPDKPISTKPAEVRMGNGK---------GNPEYYVAEIQP-GKIVFEI--VG-- VPEELAREAFRLAAAKLPLRTTF-VKKEQRLRRSRQTRIRI----AQQGVARLTVNRTNLHIYANVISD---D--GSKVL ASASTA-EAEV-RQSL-GAAGKG-GNAAAARIIGLRIAEK--AKAAG-IQKVAFDRAGFAYH--GRVKALADAAREAGLQ F-------------------------------------------------------------MPE-THAILRGVRLSVDK GRLVADLIRGKKVDQALNILNFT---------------------------------QKKAAGIIRKVLESAIAN----A- EHND-SADIDELKVKTIHVEQGTTLKRSAARAKGRGNRISKPTCHVYVTVGNMNKIRKGDEVIVLAGR------DK-GKR GTVSQRKDDSY---LL--IEGINLVKKHAK----PN--PLKGTT-GGIIQKTMPIHQSNVA-VFNAAT-------GK--A --DRVGIKV---QS--------DGRVR---VFKSSG---TEI--MGQKIHPTGFRLA--VS-RNWASRWYA------DNR D--FAGMLAEDIKVREYL--KTKLK-----NAAVSRILIERPA-K-NARITIYSARPGVVIGKKGEDIESLKKELAVRVA VNIEEVRK---PEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRL-GAQGIKIMSSGRLNGIEIARCEWYREGRVPL- -HTLRADIDYGTSEAKTTYGVIGVKVWVYMSMSDPIADLLTRIRNAQMVAKPTVMV-PSSKVKVAIAQVLKDEGYIDGFQ VKT----E---A----GKSELEIALKYY----AG-------R---PVIERIERVSRPGLRVYKGRDAIPQVMNGLGVAIV TTPKGVMTDRKARATGVGGEVLCYVAMSKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRS PHVNKTSR-DQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLKRTLIGKVVSDKRQKTVTVLVERRVKHELYG KIIARSSKYHAHDEK--GEYKLGDMIEITESRPLSKTKNWVASRLVQKA------------------------------- -MTRSL-KKGPFVDH-HLLAKVEKAVA---TKDKK----PVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYVTD-QMVGH KLGEFALTRTFKGHP------A---DK----KVK------K- >CHLAM_Candidatus_Protochlamydia_amoebophila_UWE25 Concatenation of 2 sequences M-FKKYRPVTPGTRQLALPTNEQ-LTRP----CENSRATVKP-TKSLLLPKRRTNGRNNNGHITCRH-KGGGHKQH---- YRIVDFK-R--DK-ENIPAKVASIEYDPNRTAYIALLNYA-DGEKRYILAPQGLKAGDKVQTSD-E-PP-FHIGCCMKLR LMPLGSVIHNIELYPGKGGKLVRSAGLSAQLMAR--SGGYATIRMPSGEVRMINENCRATFGAVSNPERNLRVEGKAGRM -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGKH----KGNT-PQTP---WGLYTKGLVTR-SNKKSNK---LIVKRR --------------------------------MAL---T-MMGKKRGMIQLFD-EKGN---------AIVCTVIQAEPNV ITQIK----TKE----T--DGY--TALQLGF-------EKVTGTGK----------PRLGHFK----------------- ---AG-VESRRFLVESRL--------DSTEEY-----TL---GQ-EISV--D-T-FNGIEFVDATAISKGKGYQGVMKRH NFAG-GPASHGS-GHHRH-AGSTGMR-STPG-RGLPGGKKAGQMGNERVTVQNLRIVKVDSENH---------------- ----------VIVVKGQ-VPGPRNGLVYIT----------------------------------------MIKDYIVALR ANARQWSASTKTRAE--------VK-HTTKKAH---------PQKGQGRAR--------HGS---TV-AP----QY---- RGGGRAFGPR-PKFDQHVRINKKERKAAIRFLLSEKLKEN----------------K-VWLIEDT----AMD-A------ --PKTKLFLGETETEDKHN---HFVKSMRNLPRAN-F---------------MLASNINGYDVMIARE----IVLTESAL NELNSRLKKRYLADV----KPELQKKFAYKNLMQVPGLVKVVINMGIA-EASKDKNSIQDCVKEMTMLSGQKPVITKAKK AISNFKLREDQPIGVKVTLRGQRMFDFIDRFVNIVCPRIRDFRGFPS-KC-DGMGNYTLGLDDQQIFPEIN-----LDEV KRTQGMHITFVTS-----------------------AKTDEECVELLRLLGIPFMSRKG-K--LPISLPNGVEVK-V--- -S-N--T-EVAVKGPKGALTQKL-IPG----VNVNVEG-NE--VLV---SL-A--DEEAKLA-HFHGLYRTLIHNMVVGT TEGFEKKLEMIGVGY--RAAVQG-DL--LDLQ--LGFSHPCKLPI-P-K-GLAVKVD--K-NTLITISG-FDKHLVGQFA ATVRSQR------PPEPY---QGKGIRYAGEFVRKKAGK----------MIQQESELEVADNSGAKRVKCFKVLG-SKRR Y--AHVGDIVVASVQDAHPE-G-------SVKKGDVVKVVIIRTKSYIKRKDGTKIRFDTNSCVLID-DKKN-PKGTRIF GPVAREVR-DRDFLKISSLAPEVIIT-L--NTLKDSTRK-RKPRKRVG-RGIGSKH-GKTCGRGEKGAGARSGYK-R--- -RLGK-E-GGQMPLFMKLPL-RG--FSNINLDQIVDELSLRER-GFISIK---------LLG--NGD-L-T-K-K-VKI- HVHAISESAREKLTQAKVSFMK---MQK--GQF---AGLS-KGANFVHFG----------EYGIQVL--ERGWITNQQIE ACRVAINRFF------QRRGKVWIRIFPDKPITKKPAEVRMGKGK---------GAVDHWVAVVRP-GRILFEV--AN-- VPKDMAQSALRRAAAKLGLKTRF-VTAKLRVKRAVRVRKHL---RGTGLKPRLCVVKSNSHIQAQLIDD---E--TGTTL GGTATF-AKEY-RNTE----FCK-KNKASARKLGEQIAEI--AKSKN-IKEVVFDRGPFKYH--GILAELANAARAGGLQ F--------------------------------------------------------------MSYAKAISKYIRISPRK ARLAAGLIRGLSVSDASLQLTFS---------------------------------GLKGGRLLKKTLDSAVAN----A- ETQL-DMRRENLKVVEVRVDAGPTLKRAKPKNRGGRHPIMKRTSHFTVIVSNSKKIRQGDTVVAIAGN------SR-GQI GTVQSCKGD----RVI--VQGLNVRKKHVK----RS--QE-APK-GRIVEIERPIHISNLK-VCVEG--------ET--T --AKLKVRT---NE--------QGQFV---YHKDDQ---EVV--MGQKVNPISFRLV--RT-RDWRSKWFA------NKK E--FGDLLVEDQIIRAYL--LKKPA-----LVGVSAIKIKRMS-G-KVEVTIVTARPGLVIGKKGAEIDVLKGELSKLVW VAVEEVKR---PDMDAKIVADSIAKQLERRIPFRRAMKKAMQSSIDA-GAFGIKVQLSGRIGGAEIARTEWYKEGSTPL- -HTLRADIDYATGRAETTYGSIGVKVWIYMVVSDPVADFLTRIRNGTKAQHRYVDV-NWSKMKQTLAEILKNQGFIENYL VKV----D--EG----QRGTIRIFLKYT---NGR-------R---PVIQGLKRISKPGLRKYVGHQDIPRFYGNMGLSIV STSQGVMAGNEATQRGIGGELLCLIWSARQKIRIRLKGYDQRLLDRSTGDIVETAKRTGAAIAGPIPLPTSCEKFTVLRS PNIDRKSR-EQFEIRTHRRLIDILNPTSKTIDALKTLTLPAGVDIKIKARKVKKGIVVSNKMQKTVVVKVERTFAHPQYG KIVTRGKKYYAHNES--GDLQIGDEVKIMETRPLSKLKRWRVVA------------------------------------ -MARSL-KKGPFVDH-HLQKKVDVQNK---EGTKK----PIKTWSRRSMITPDMVGHTFEVHNGRKHLTVFVTD-NMVGH RLGEFSPTRTFKGHP----------------IKK-------- >CHLAM_Chlamydia_muridarum_Nigg Concatenation of 2 sequences -MFKKFKPVTPGTRQLILPSFDE-LTTQGELEGSSSKRSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGVRRH---- YRVIDFK-R--NK-DGVEAKVASVEYDPNRSAYIALLNYV-DGEKRYILAPKGIKRGDRVISGE-G-SP-FKTGCCMTLK SIPLGISVHNVEMRPGSGGKLVRSAGLSAQIIAK--TDGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRR -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-SQTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LIGKKEGMMHVFD-KNGN---------LVACSVISIEPNV VAQLK----TAS----S--DGY--NAVQMGADAVKAPEKT--IFSK----------ALLGHFK----------------- ---SG-GCAFRVLKEVVV------SEEAVQSV-----SL---GD-EFGV--E-I-FDGVSNVDVCGISKGKGFQGVMKKF GFRG-GPKSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRK---------------- ----------VMLVKGA-IPGFKGSVVVVK-MVLLSKFD-FSGKES-GKVELPDAFF----A--EG-KEQSVKDYLVAIQ ANKRQWSACTRGRSE--------VS-HSTRKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHVRINKKERRAAIRLLLAQKIQTG----------------K-LIVADNSVFISSLN-A------ --PKTKLFVDGLDHVGSNE---NLRLSVRNLAAVRGF---------------TYGENINGYDIAAARN----IVVSEKAL ELLVSRLKKLYTEEI----RKTLQDKFQYENVMQIPVLKKIVISMGLA-EAAKDKNLFQSHLEELAVISGQKPLVTRAKN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSC-KG-DGRGCYSLGLDDQQIFPEVD-----LDRV KRSQGMNITWVTT-----------------------AQTDAECLTLLECMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--D-EISVKGPKGSLTQVL--AK-E--VEIAVKG-NE--VFV----S-PAAHIIDRPG-RMQGLYWALIANMVKGV HLGFEKRLEMIGVGF--RASVQG-SF--LDLS--IGVSHPTKMPI-P-T-GLEVSVE--K-NTLISIKG-INKQLVGEFA ACVRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPD-S-------SVKKGDVVKAVIVRTRNDIRRKDGSTLRFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFIKISSLAPEVIIK-L--EYLQDPSPR-KRRTKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLVSLETLKQR-KVIHVK---------VIL--KGA-L-D-K-KLVWKD AAIVLSEGVKSLIETV-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWITSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIRTRF-VKTSGKARRALRVRKAL---KGSSLKPRLSVVKTNKHIYVQLIDD---V--EGKTL ASISTL-AKIS-KTSG----LTK-KNQDNAKALGVKIAEL--GKSLQ-VDRIVFDRGAHKYH--GVVAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNRSVVEAQQQLSFS---------------------------------QMKAGRCLKKVLDSAVAN----A- ESNE-NVKRENLCVVEVRVDAGPMFKRVKSKSRGGRAPVLKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLRCLKD----KVV--VEGINVRVKNIK----RS--QE-NPK-GKRINIEAPLHISNVR-LSIDNQ-----------P --ARLFVKV---TE--------KGREL---WNKHSDGSSSLY--MGQKGCPVGFRTA--VT-KKWRSLWYG------NNQ E--FGKFLIEDVRIREFL--KKKPS-----CQGAAGFVVKRMS-G-KIEVTIHTARPGLVIGKKGAEVESLKAELKKLVW VEIAEVKR---PELNAQLVADGIAKQIERRVSFRRAMKKALQSVMDA-GALGVKVQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGIKVWINGITSDSIANLLTRIRNALMAEHLYIDI-EHSKMLEAIVRILKQHGFVAHFL VKE----E---N----RKRLMRVFLRYG---EDR-------R---PVIHALKRVSKPSRRVYVSAAKIPYVFGNMGIAVL STPQGVLEGSEARAKNVGGELLCLVWQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKARKTKIGVVVSSKMEKTVVVRVERVYSHPQYA KVVRDSSKYYAHNEL---DVKEGDTVRIQETRPLSKTKRWRVVD---RV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRDMNA---LEKKT----PIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSE-TMVGH KLGEFSPTRMFKSHP------V---------KKG-------- >CHLAM_Chlamydia_trachomatis_434/Bu Concatenation of 2 sequences -MFKKFKPVTPGTRQLILPSFDE-LTTQGELKGSSSRRSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGVRRH---- YRVIDFK-R--NK-DGIEAKVASVEYDPNRSAYIALLNYV-DGEKRYILAPKGIKRGDRVISGE-G-SP-FKTGCCMTLK SIPLGLSVHNVEMRPGSGGKLVRSAGLSAQIIAK--TAGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRR -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-SQTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LIGKKEGMMHVFD-KNGN---------LVACSVISVDANV VAQLK----TAS----S--DGY--NAVQIGADVVQAPEKT--IFSK----------ALLGHFK----------------- ---SG-GRACRVLKEVVV------SEEAVQSV-----SL---GD-EFGL--E-I-FDGVSNVDICGISKGKGFQGVMKKF GFRG-GPKSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRK---------------- ----------VMLVKGA-IPGFKGSVVVVK-MVLLSKFD-FSGKEL-GKFELPDAFF-----T-EG-REQSVKDYLVAIQ ANKRQWSACTRGRSE--------VS-HSTKKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHIRINKKERRAAIRLLLAQKIQTG----------------K-LIVAENSVFVSSLD-A------ --PKTKLFVDSLAHVGSNE---NLRLSVRNLSAVRGF---------------TYGENISGYDIAAARN----IVVSEKAL ELLVSRLKKLYTEEI----RKTLQDKFQYENVMQIPVLKKIVISMGLA-EAAKDKNLFQAHLEELAVISGQKPLVTRAKN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSC-KG-DGRGCYSLGLDDQQIFPEVD-----LDRV KRSQGMNITWVTT-----------------------AQTDAECLTLLECMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--D-EISVKGPKGSLTQVL--AK-E--VEIAVKG-NE--VFV----A-PAAHVVDRPG-RMQGLYWALIANMVKGV HTGFEKRLEMIGVGF--RAAVQG-SL--LDLS--IGVSHPTKMPI-P-T-GLEVSVE--K-NTLISIKG-INKQLVGEFA ACVRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDIEPD-S-------SVKKGDVVKAVIVRTRNDIHRKDGSTLRFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFVKISSLAPEVIIK-L--ECLQDPSPR-KRRTKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLVSLEALKER-KVIHVK---------VIL--KGA-L-D-K-KLVWKD AAIVLSEGVKSLIEAV-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWITSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIRTRF-VKTSGKARRALRVRKAL---KGCSLKPRLSVVKTNKHVYVQLIDD---V--EGKTL AFISTL-AKVA-KTSG----LTR-KNQDNAKALGIKIAEL--GKGLQ-VDRVVFDRGAHKYH--GVVAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNRSVVEAQQQLSFS---------------------------------QMKAGRCLKKVLDSAIAN----A- ESNE-NIKRENLCVLEVRVDAGPMFKRMKSKSRGGRAPILKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLRCLKD----KVV--VEGINVRVKNIK----RS--QE-NPK-GKRINIEAPLHISNVR-LSIDNQ-----------P --ARLFVKV---TE--------KGREL---WNKHSDGSSSLY--MGQKGCPVGFRTA--VT-KKWRSLWYG------NNQ E--FGKFLIEDVKIREFL--KKKPS-----CQGAAGFVVKRMS-G-KIEVTIHTARPGLVIGKKGAEVESLKAELKKLVW VEIAEVKR---PELNAQLVADGIAKQIERRVSFRRAMKKALQSVMDA-GALGVKVQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGIKVWINGMTSDSIANLLTRIRNALMAEHLYIDI-EHSKMLEAIVRILKQHGFVAHFL VKE----E---N----RKRLMRVFLRYG---EDR-------R---PVIHALKRVSKPSRRVYVSAAKIPYVFGNMGIAVL STPQGVLEGSVARAKNVGGELLCLVWQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKARKTKIGVVVSSKMEKTVVVRVERVYSHPQYA KVVRDSSKYYAHNEL---DVKEGDTVRIQETRPLSKTKRWRVVG---RV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRDMNA---LEKKT----PIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSE-TMVGH KLGEFSPTRMFKSHP------V---------KKG-------- >CHLAM_Chlamydia_trachomatis_A/HAR-13 Concatenation of 2 sequences -MFKKFKPVTPGTRQLILPSFDE-LTTQGELKGSSSRRSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGVRRH---- YRVIDFK-R--NK-DGIEAKVASVEYDPNRSAYIALLNYV-DGEKRYILAPKGIKRGDRVISGE-G-SP-FKTGCCMTLK SIPLGLSVHNVEMRPGSGGKLVRSAGLSAQIIAK--TAGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRR -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-SQTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LIGKKEGMMHVFD-KNGN---------LVACSVISVDANV VAQLK----TAS----S--DGY--NAVQMGADVVQAPEKT--IFSK----------ALLGHFK----------------- ---SG-GRVCRVLKEVVV------SEEAVQSV-----SL---GD-EFGL--E-I-FDGVSNVDICGISKGKGFQGVMKKF GFRG-GPKSHGS-GFHRH-AGSTGMR-STPG-RCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRK---------------- ----------VMLVKGA-IPGFKGSVVVVK-MVLLSKFD-FSGKES-GKFELPDAFF-----T-EG-KEQSVKDYLVAIQ ANKRQWSACTRGRSE--------VS-HSTKKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHIRINKKERRAAIRLLLAQKIQTG----------------K-LIVAENSVFVSSLD-A------ --PKTKLFVDGLAHVGSNE---NLRLSVRNLSAVRGF---------------TYGENISGYDIAAARN----IVVSEKAL ELLVSRLKKLYTEEI----RKTLQDKFQYENVMQIPVLKKIVISMGLA-EAAKDKNLFQAHLEELAVISSQKPLVTRARN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSC-KG-DGRGCYSFGLDDQQIFPEVD-----LDRV KRSQGMNITWVTT-----------------------AQTDAECLTLLECMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--D-EISVKGPKGSLTQVL--AK-E--VEIAVKG-NE--VFV----T-PAAHVVDRPG-RIQGLYWALIANMVKGV HTGFEKRLEMIGVGF--RAAVQG-SL--LDLS--IGVSHPTKMPI-P-T-GLEVSVE--K-NTLISIKG-INKQLVGEFA TCVRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPD-S-------SVKKGDVVKAVIVRTRNDIHRKDGSTLRFDTNSCVIID-DKGN-PKGTRIF GPIAREIR-DRGFVKISSLAPEVIIK-L--ECLQDPSPR-KRRTKLLG-RGPSSGH-GKTSSRGHKGDCSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLVSLEALKER-KVIHVK---------VIL--KGA-L-D-K-KLVWKD AAIVLSEGVKSLIEAV-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWITSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVVVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIRTRF-VKTSGKARRALRVRKAL---KGCSLKPRLSVVKTNKHVYVQLIDD---V--EGKTL ASISTL-AKVA-KTSG----LTR-KNQDNAKALGIKIAEL--GKGLQ-VDRVVFDRGAHKYH--GVVAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNRSVVEAQQQLSFS---------------------------------QMKAGRCLKKVLDGAIAN----A- ESNE-NIKRENLCVLEVRVDVGPMFKRMKSKSRGGRAPILKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLRCLKD----KVV--VEGINVRVKNIK----RS--QE-NPK-GKRINIEAPLHISNVR-LSIDNQ-----------P --ARLFVKV---RE--------KGREL---WNKHSDGSSSLY--MGQKGCPIGFRTA--VT-KKWRSLWYG------NNQ E--FGKFLIEDVKIREFL--KKKPS-----CQGAAGFVVKRMS-G-KIEVTIHTARPGLVIGKKGAEVESLKAELKKLVW VEIAEVKR---PELNAQLVADGIAKQIERRVSFRRAMKKALQSVMDA-GALGVKVQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGIKVWINGMTSDSIANLLTRIRNALMAEHLYVDI-EHSKMLEAIVRILKQHGFVAHFL VKE----E---N----RKRLMRVFLRYG---EDR-------R---PVIHALKRVSKPSRRVYVSAAKIPYVFGNMGIAVL STPQGVLEGSVARAKNVGGELLCLVWQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKARKTKIGVVVSSKMEKTVVVRVERVYSHPQYA KVVRDSSKYYAHNEL---DVKEGDTVRIQETRPLSKTKRWRVVG---RV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRDMNA---LEKKT----PIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSE-TMVGH KLGEFSPTRMFKSHP------V---------KKG-------- >CHLAM_Chlamydia_trachomatis_D/UW-3/CX Concatenation of 2 sequences -MFKKFKPVTPGTRQLILPSFDE-LTTQGELKGSSSRRSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGVRRH---- YRVIDFK-R--NK-DGIEAKVASVEYDPNRSAYIALLNYV-DGEKRYILAPKGIKRGDRVISGE-G-SP-FKTGCCMTLK SIPLGLSVHNVEMRPGSGGKLVRSAGLSAQIIAK--TAGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRR -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-SQTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LIGKKEGMMHVFD-KNGN---------LVACSVISVDANV VAQLK----TAS----S--DGY--NAVQMGADVVQAPEKT--IFSK----------ALLGHFK----------------- ---SG-GRVCRVLKEVVV------SEEAVQSV-----SL---GD-EFGL--E-I-FDGVSNVDICGISKGKGFQGVMKKF GFRG-GPKSHGS-GFHRH-AGSTGMR-STPG-RCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRK---------------- ----------VMLVKGA-IPGFKGSVVVVK-MVLLSKFD-FSGKES-GKFELPDAFF-----T-EG-KEQSVKDYLVAIQ ANKRQWSACTRGRSE--------VS-HSTKKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHIRINKKERRAAIRLLLAQKIQTG----------------K-LIVAENSVFVSSLD-A------ --PKTKLFVDGLAHVGSNE---NLRLSVRNLSAVRGF---------------TYGENISGYDIAAARN----IVVSEKAL ELLVSRLKKLYTEEI----RKTLQDKFQYENVMQIPVLKKIVISMGLA-EAAKDKNLFQAHLEELAVISSQKPLVTRARN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSC-KG-DGRGCYSFGLDDQQIFPEVD-----LDRV KRSQGMNITWVTT-----------------------AQTDAECLTLLECMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--D-EISVKGPKGSLTQVL--AK-E--VEIAVKG-NE--VFV----T-PAAHVVDRPG-RIQGLYWALIANMVKGV HTGFEKRLEMIGVGF--RAAVQG-SL--LDLS--IGVSHPTKMPI-P-T-GLEVSVE--K-NTLISIKG-INKQLVGEFA ACVRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPD-S-------SVKKGDVVKAVIVRTRNDIHRKDGSTLRFDTNSCVIID-DKGN-PKGTRIF GPIAREIR-DRGFVKISSLAPEVIIK-L--ECLQDPSPR-KRRTKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLVSLEALKER-KVIHVK---------VIL--KGA-L-D-K-KLVWKD AAIVLSEGVKSLIEAV-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWITSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVVVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIRTRF-VKTSGKARRALRVRKAL---KGCSLKPRLSVVKTNKHVYVQLIDD---V--EGKTL ASISTL-AKVA-KTSG----LTR-KNQDNAKALGIKIAEL--GKGLQ-VDRVVFDRGAHKYH--GVVAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNRSVVEAQQQLSFS---------------------------------QMKAGRCLKKVLDGAIAN----A- ESNE-NIKRENLCVLEVRVDVGPMFKRMKSKSRGGRAPILKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLRCLKD----KVV--VEGINVRVKNIK----RS--QE-NPK-GKRINIEAPLHISNVR-LSIDNQ-----------P --ARLFVKV---RE--------KGREL---WNKHSDGSSSLY--MGQKGCPIGFRTA--VT-KKWRSLWYG------NNQ E--FGKFLIEDVKIREFL--KKKPS-----CQGAAGFVVKRMS-G-KIEVTIHTARPGLVIGKKGAEVESLKAELKKLVW VEIAEVKR---PELNAQLVADGIAKQIERRVSFRRAMKKALQSVMDA-GALGVKVQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGIKVWINGMTSDSIANLLTRIRNALMAEHLYVDI-EHSKMLEAIVRILKQHGFVAHFL VKE----E---N----RKRLMRVFLRYG---EDR-------R---PVIHALKRVSKPSRRVYVSAAKIPYVFGNMGIAVL STPQGVLEGSVARAKNVGGELLCLVWQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKARKTKIGVVVSSKMEKTVVVRVERVYSHPQYA KVVRDSSKYYAHNEL---DVKEGDTVRIQETRPLSKTKRWRVVG---RV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRDMNA---LEKKT----PIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSE-TMVGH KLGEFSPTRMFKSHP------V---------KKG-------- >CHLAM_Chlamydia_trachomatis_L2b/UCH-1/proctitis Concatenation of 2 sequences -MFKKFKPVTPGTRQLILPSFDE-LTTQGELKGSSSRRSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGVRRH---- YRVIDFK-R--NK-DGIEAKVASVEYDPNRSAYIALLNYV-DGEKRYILAPKGIKRGDRVISGE-G-SP-FKTGCCMTLK SIPLGLSVHNVEMRPGSGGKLVRSAGLSAQIIAK--TAGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRR -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-SQTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LIGKKEGMMHVFD-KNGN---------LVACSVISVDANV VAQLK----TAS----S--DGY--NAVQIGADVVQAPEKT--IFSK----------ALLGHFK----------------- ---SG-GRACRVLKEVVV------SEEAVQSV-----SL---GD-EFGL--E-I-FDGVSNVDICGISKGKGFQGVMKKF GFRG-GPKSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRK---------------- ----------VMLVKGA-IPGFKGSVVVVK-MVLLSKFD-FSGKEL-GKFELPDAFF-----T-EG-REQSVKDYLVAIQ ANKRQWSACTRGRSE--------VS-HSTKKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHIRINKKERRAAIRLLLAQKIQTG----------------K-LIVAENSVFVSSLD-A------ --PKTKLFVDSLAHVGSNE---NLRLSVRNLSAVRGF---------------TYGENISGYDIAAARN----IVVSEKAL ELLVSRLKKLYTEEI----RKTLQDKFQYENVMQIPVLKKIVISMGLA-EAAKDKNLFQAHLEELAVISGQKPLVTRAKN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSC-KG-DGRGCYSLGLDDQQIFPEVD-----LDRV KRSQGMNITWVTT-----------------------AQTDAECLTLLECMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--D-EISVKGPKGSLTQVL--AK-E--VEIAVKG-NE--VFV----A-PAAHVVDRPG-RMQGLYWALIANMVKGV HTGFEKRLEMIGVGF--RAAVQG-SL--LDLS--IGVSHPTKMPI-P-T-GLEVSVE--K-NTLISIKG-INKQLVGEFA ACVRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDIEPD-S-------SVKKGDVVKAVIVRTRNDIHRKDGSTLRFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFVKISSLAPEVIIK-L--ECLQDPSPR-KRRTKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLVSLEALKER-KVIHVK---------VIL--KRA-L-D-K-KLVWKD AAIVLSEGVKSLIEAV-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWITSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIRTRF-VKTSGKARRALRVRKAL---KGCSLKPRLSVVKTNKHVYVQLIDD---V--EGKTL AFISTL-AKVA-KTSG----LTR-KNQDNAKALGIKIAEL--GKGLQ-VDRVVFDRGAHKYH--GVVAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNRSVVEAQQQLSFS---------------------------------QMKAGRCLKKVLDSAIAN----A- ESNE-NIKRENLCILEVRVDAGPMFKRMKSKSRGGRAPILKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLRCLKD----KVV--VEGINVRVKNIK----RS--QE-NPK-GKRINIEAPLHISNVR-LSIDNQ-----------P --ARLFVKV---TE--------KGREL---WNKHSDGSSSLY--MGQKGCPVGFRTA--VT-KKWRSLWYG------NNQ E--FGKFLIEDVKIREFL--KKKPS-----CQGAAGFVVKRMS-G-KIEVTIHTARPGLVIGKKGAEVESLKAELKKLVW VEIAEVKR---PELNAQLVADGIAKQIERRVSFRRAMKKALQSVMDA-GALGVKVQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGIKVWINGMTSDSIANLLTRIRNALMAEHLYIDI-EHSKMLEAIVRILKQHGFVAHFL VKE----E---N----RKRLMRVFLRYG---EDR-------R---PVIHALKRVSKPSRRVYVSAAKIPYVFGNMGIAVL STPQGVLEGSVARAKNVGGELLCLVWQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKARKTKIGVVVSSKMEKTVVVRVERVYSHPQYA KVVRDSSKYYAHNEL---DVKEGDTVRIQETRPLSKTKRWRVVG---RV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRDMNA---LEKKT----PIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSE-TMVGH KLGEFSPTRMFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_abortus_S26/3 Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTTQGELSGKKTRKSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGAKRL---- YRVIDFK-R--NK-DGIEAKVVSVEYDPNRSAYIALLSYA-DGEKRYILAPKGIKRGDQVISGE-G-SP-FKLGCCMTLK SMPLGSTVHNIEMRPHSGGKLVRSAGLAAQVIAK--TPGYVTLKMPSGEFRMLNEGCRATIGEVSNSDHNLCVDGKAGRK -RWK-----GIR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LMGKKEGMIHVFD-KDGN---------LVACSVISMSSNV VTQIK----VDS----T--DGY--NAIQMGA-------NE--IVNK----------PSIGHFK----------------- ---SG-SRVFRELKEVRL------SEEAVNEV-----SL---GS-EFGL--E-V-FESVSSIDVSGVSKGKGFQGVMKRF GFRG-GPQSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGTVNVTVKNLEVIKIDLEKK---------------- ----------VLLVKGA-IPGPRGSVVVVR-MVLLSKFD-FFGNKA-GEVELPDAFF----AQ-EGSGLQLVKDYLVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHVRINKKEKRAAIRLLLSQKIQTN----------------H-LIVADDSVFTNSLT-S------ --PKTKLFI---DDLEHAQNNESLRLSLRNLPAVRGF---------------TYGMNINGYDLVSARN----IVISEKAL NRLSSRLKKLYTEEI----RKTLQEKFGYSNTMQIPVLKKIVISMGLA-EAAKDKNLFQAHLDELSMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGQRMYDFMDRFCHIVSPRIRDFRGFSS-KG-DGRGCYSLGLDDQQIFPEVD-----LDRV KRTQGMNITWVTT-----------------------AQTDVECTTLLELMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--N-EILVKGPKGSLKQVL--AP-E--VVIDIKG-RE--VFV--HPA-P--YVVDRPS-RMQGLFWALISNMVQGV SVGFEKRLEMIGVGF--RASVQG-SI--LDLS--IGVSHPTKIPI-P-A-DIQVSVE--K-NTIISVKG-INKQLVGEFA ANIRAKR------KPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKRVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPD-S-------SVKKGDVVKAVIVRTRRNILRKDGSSLKFDTNSCVIID-EKGN-PKGTRIF GPIAREIR-DRGFVKISSLAPEVIIK-L--ESLQDPSPR-KRRTKLLG-RGPSSGH-GKTSCRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLITLEALKQK-KAIDVK---------VIV--KGD-L-E-K-TFIWKD ANVVLSQGVRNLIGVA-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWVTSRQIE ACRIAINRYL------KRRGKVWIRIFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSREDAQDALRRAAAKLGIRTRF-VKSEKKVRRALRVRKVL---RGSSLKPRLSVVKTNKHIYVQLIDD---S--IGKTL ASVSTI-AKSS-KAAG----LVK-KNQGVAKALGVQIAEI--GKSLQ-VDRVVFDRGPFKYH--GIIAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVTEAQQQLSFS---------------------------------QLKAGRCLKKVLDSAVAN----A- ELHD-NVKREKLNVIEVRVDAGPVYKRAKSKSRGGRSPILKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLSCLREKN--KVV--VEGVNVRTKNIK----RS--QE-NPK-GKRINIEAPIHISNVR-LSIDGA-----------P --AKLSVKV---TE--------NGREL---WNKSSDGTSKLY--MGQKGCPIGFRTG--VT-KKWRSLWYG------NKQ E--FGKFLIEDVKIREFL--RKKPS-----CQGAAGFVVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRKLVW VEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDA-GAVGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYAAASAATTYGIIGVKVWINGMTSDTIADLLTRIRNALKAEHLYVDL-EHSKMREAIVKILKQHGFLAHYL IKE----E---H----RKRTMRIFLQYT---NDR-------K---PVIRQLKRVSKPSRRVYVPAAKIPYVFGNMGISVL STSQGVLDGSTARAKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVAGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLALPAGVDIKIKARKTKIGVVVSSKMDKTVVVRVERIYSHPQYA KVVRDSRKFYAHDGL---GVSEGDKVKIQETRPLSKLKRWRVVE---RV------------------------------- -MSRSL-RKGPFVDH-SLIKKVRAMNL---LEKKT----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRIFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_caviae_GPIC Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTRQGELSGKKTRKSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGVKRL---- YRVIDFK-R--NK-DGIEAKVVSVEYDPNRSAYIALLNYA-DGEKRYILAPKGIKRGDEVISGE-G-SP-LKLGCCMTLK SMPLGSTVHNIEMRPNSGGKLVRSAGLAAQVIAK--TPGYVTLKMPSGEFRMLNEGCKATIGEVSNSDHNLCVDGKAGRK -RWK-----GVR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LMGKKEGMIHVFD-KDGN---------LVACSVISVGSNV VTQIK----VDS----T--DGY--NAIQMGA-------NE--IMNK----------PELGHLK----------------- ---SG-SRVFGLLKEVRL------SEDAINEV-----SL---GN-EFGL--E-V-LEDISSVDISGVSKGKGFQGVMKRF GFRG-GPKTHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGTVNVTVKNLEVVKIDLEKK---------------- ----------VLLVKGA-IPGPRGSVVVIR-MVLLSKFD-FSGNKA-GEVELPDAFF-----VQEGNGLQLVKDYLVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------KQKGTGNAR--------QGC---LA-SP----QF---- RGGGVVFGPK-PKFDQHVRINRKEKRAAIRLLLSQKIQTN----------------R-LIVADDSVFTSSLA-S------ --PKTKLFI---DDLDHAQNNEGLRLSLRNLSAVRGF---------------TYGMNINGYDLASARN----VVISEKAL KGLASRLKKLYTEEI----RKSLQEKFGYGNTMQIPVLRKIVISMGLA-EAAKDKNLFQAHLEELSMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGQRMYDFMDRFCNIVSPRIRDFRGFSM-KG-DGRGCYSLGLDDQQIFPEID-----LDRV KRTQGMNITWVTT-----------------------AQTDVECTTLLELMGLRFMSRKA-R--DPIVLPQGVEVS-I--- -Q-N--N-EILVKGPKGSLKQVL--AP-E--VVVDIKD-RE--VFV----HAPHVVD-RPSR--MQGLFWALISNMVQGV NTGFEKRLEMIGVGF--RAAVQG-SV--LDLS--IGVSHPTKMPI-P-A-ELQVSVE--K-NTLISVKG-INKQLVGEFA ASIRAKR------RPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDIIVCSVRDVEPD-S-------SIKKGDVVKAVIVRTRRDILRKDGSSLRFDTNSCVIID-EKGN-PKGTRIF GPIAREIR-DRGFVKISSLAPEVIIK-L--ESLQDPSPR-KRRTKLLG-RGPSSGH-GKTSCRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLITLDALKEK-RAIDVK---------VIV--KGE-L-E-K-TFIWKD ANVVLSQGVRNLIGVA-----K---QQK--GQF---AGLS-KGATFVDFG----------EFGMQTL--ERGWVTSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSREDAQDALRRAAAKLGIRTRF-VKSEKKVHRALRVRKVL---RGSSLKPRLCVVKTNKHIYVQLIDD---S--IGKTL ASVSTM-AKSN-KASG----LIK-KNQDVAKTLGTQIAEI--GKSLQ-VDRVVFDRGPFKYH--GIIAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVMEAQQQLNFS---------------------------------QLKAGRCLKKVLDSAVAN----A- VLNE-NVKREQLSVIEVRVDAGPVYKRAKSKSRGGRSPILKRTSHLTVIVGERYSVCVGDTVYVLAGN------DK-GKQ GKVLSCLREKN--KVV--VEGVNVRTKNIK----RS--QE-NPK-GKRISIEAPIHVSNVR-LSIDGA-----------P --AKLSVKV--NGRE--WNKSPDGTSK---LYRSVK---ERK--MGQKGCPIGFRTA--VT-KKWRSLWYG------NKQ E--FGKFLIEDVKIREHL--RKKPS-----CQGAAGFIVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRKLVW VEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDA-GAIGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGVKVWINGMTSDTIADLLTRIRNALKAEHLYVDL-EHSKMREAIVRILKQHGFLAHYL VKE----E---N----RKRTMRIFLQYS---NDR-------R---PVIRQLKRVSKPSRRVYVPAAKIPYVFGNMGISVL STSQGVLDGATARAKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVAGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLALPAGVDIKIKARKTKVGVVVSSKMDKTVVVRVERIYSHPQYA KVVRDSKKYYAHNGL---DVSEGDKVKIQETRPISKLKRWRVVE---RV------------------------------- -MSRSL-RKGPFVDH-HLIKKVRAMNL---LEKKS----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRIFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_felis_Fe/C-56 Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTRQGDLTGKRTRKSVRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGAKRL---- YRVIDFK-R--NK-DGIEAKVVSVEYDPNRSAYIALLNYA-DGEKRYILAPKGIKRGDQVISGE-G-SP-FKLGCCMTLK SMPLGSTVHNIEMRPHSGGKLVRSAGLAAQVIAK--TPGYVTLKMPSGEFRMLNEGCRATIGEVSNADHNLCVDGKAGRK -RWK-----GVR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKRK-SN-K-WIVKDR --------------------------------SQL---S-LMGKKEGMIHVFD-KDGN---------LVACSVISMSPNV VSQIK----VDS----T--DGY--NAIQMGA-------DEISVVNK----------PILGHFK----------------- ---SG-SRVFRTLKEVRV------SEDAVNEA-----SL---GS-EFGL--E-V-FEDVSSVDISGVSKGKGFQGVMKKF GFRG-GPKTHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGAVNVTIKNLEVIKIDLEKK---------------- ----------VLLVKGA-IPGPRGSVVVVR-MVLLSKFD-FFGNKA-GEVELPDAFF----AQ-EGNGLQLVKDYIVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------RQKGTGNAR--------QGC---LA-AP----QF---- RGGGIVFGPK-PKFDQHVRINKKEKRAAIRLLLSQKIQTN----------------R-LIVADDSVFTKSLT-A------ --PKTKLFI---DDLNHAQNNEGLRLSLRNLPAVRGF---------------AYGMNVNGYDLVSARN----IVISEKAL TGLVSRLKKLYTEEI----RKSLQEKFGYTNTMQIPVLKKIVISMGLA-EAAKDKNLFQAHLEELSMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGERMYDFMDRFCNIVSPRIRDFRGFSK-KG-DGRGCYSLGLEDQQIFPEVD-----LDRV KRTQGMNITWVTT-----------------------AQTDAECTTLLELMGLRFMSRKA-R--DPIVLPQGVEVS-L--- -Q-N--N-EIVVKGPKGSLTQTL--AP-E--VVVEIKD-KE--VFV--SPA-P--NVVDRPS-RVQGLFWALISNMVQGV SAGFEKRLEMIGVGF--RAAVQG-SV--LDLS--IGVSHPTKIPI-P-A-DIQVTVE--K-NTLISVKG-INKQLVGEFA ANIRAKR------RPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDIIVCSVRDVEPD-S-------SIKKGDVVKAVIVRTRRDILRKDGSSLRFDTNSCVIID-EKGN-PKGTRIF GPIAREIR-DRGFVKISSLAPEVIIK-L--ESLQDPSPR-KRRKKLLG-RGPGSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTQRLITLDALKQK-KAIDVK---------VIV--KGE-L-E-K-TFIWKD ANVVLSQGVRNLIGVA-----K---QQK--GQF---AGLS-KGATFIDFG----------EFGMQTL--ERGWVTSRQIE ACRVAINRYL------KRKGKVWIRVFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIRTRF-VKSEKKIRRALRVRKVL---RGSSLKPRLSVVKTNKHIYVQLIDD---S--IGKTL ASVSTM-AKSS-KASG----LTK-KNQDVAKALGSKIAEL--GKNLQ-VDRVVFDRGPFKYH--GVIAMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVMEAQKQLSFS---------------------------------QLKAGRCLKKVLDSAVAN----A- ELNE-NVKREQLNVIEVRVDAGPVYKRTKSKSRGGRSPILKRTSHLTVIVGERRSVCVGDTVYVLAGN------DK-GKQ GKVLSCLREKN--KVV--VEGINVRTKNIK----RS--QE-NPK-GKRISIEAPIHVSNVR-LSIEGA-----------P --AKISVKV----TERLWNKFPDGTSK-YFVKERKG--------MGQKGCPIGFRTG--VT-KKWRSLWYG------NKQ E--FGKFLIEDVKIREHL--RKKPS-----CQGAAGFVVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRKLVW VEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMEA-GAIGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATASAETTYGIIGVKVWINGMTSDTIADLLTRIRNALKAEHLYVDL-EHSKMRESIVKILKHHGFLARYL VKE----E---N----RKRTMRIFLQYS---DDR-------R---PVIRQLKRVSKPSRRVYVPAAKIPYVFGNMGISVL STSQGVLDGSTARAKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVAGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLIDILDPTGKTIDALKMLALPAGVDIKIKARKTKVGVVVSSKMDKTVIVRVERVYSHPQYA KVVRDSKKYYAHNDL---NVSEGEKVRIQETRPLSKLKRWRVVE---RI------------------------------- -MGRSL-RKGPFVDH-SLIKKVRAMNL---LEKKA----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRMFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_pneumoniae_AR39 Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTTRGELRGTKSKRSLRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGAKQL---- YRVVDFK-R--NK-DGITAKVVTVEYDPNRSAYIALLSYE-DGEKRYILAPKGIQRGDVVVSGE-G-SP-FKPGCCMTLK SIPLGLSVHNIEMRPSSGGKLVRSAGLAAQVIAK--SPGYVTLKMPSGEFRMLNEGCRATIGEVSNADHNLRVDGKAGRR -RWM-----GVR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKNK-SN-K-WIVKDR --------------------------------SHI---S-VMGKKEGMIHIFD-KDGS---------LVACSVIRVEPNV VTQIK----TKE----S--DGY--FSLQIGAEEMNAPAHT--IVSK----------PKLGHLK----------------- ---AG-GRVFRFLKEVRG------SEEALNGV-----SL---GD-AFGL--E-V-FEDVSSVDVRGISKGKGFQGVMKKF GFRG-GPGSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGAENVTVKNLEVIKVDLEKK---------------- ----------VLLVKGA-IPGARGSIVIVK-MVLLSKFD-FSGNKI-GEVEVADSLF-----ADEGDGLQLIKDYIVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------KQKGTGNAR--------QGC---LA-SP----QF---- RGGGIVFGPK-PKFNQHVRINRKERKAAIRLLLAQKIQTN----------------K-LTVVDDTVFVDALT-A------ --PKTQLFIDHLDHVEKNE---NLRLSLRNLTAVKGF---------------VYGININGYDLASAHN----IVISKKAL QELVSRLKKFYTEEI----RKSLFEKFGYANKMQIPVLKKIVLSMGLA-EAAKDKNLFQAHLEELTMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSN-KG-DGRGCYSVGLDDQQIFPEIN-----LDRV KRTQGLNITWVTT-----------------------AQTDDECTTLLELMGLRFMSRKA-R--EPILLPQGVEVS-I--- -Q-D--D-KIIVKGPKGSLTQKS-VKE----VEITLKD-NS--IFV---HAAP--HVVDRPS-CMQGLYWALISNMVQGV HLGFEKRLEMIGVGF--RASVQG-AF--LDLS--IGVSHPTKIPI-P-S-TLQVSVE--K-NTLISVKG-LDKQLVGEFA ASIRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPN-S-------SIKKGDVIKAVIVRTRRHITRKDGSTLKFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFIKISSLAPEVIIK-L--ESLFDISER-KRRKKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTGRLITLDALKAK-KAIAVK---------VIL--KGD-L-E-K-TFVWQD TAVVLSQGVQNLLGIT-----K---QQK--GQF---AGLS-KGATFVDFG----------EYAMQTL--ERGWVTSRQIE ACRVAINRYL------KRRGKVWIRIFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIKTRF-VKSLMKRRRALRVRKVL---KGSPTKPRLSVVKTNKHIYVQLIDD---S--IGKTL ASVSTL-SKLN-KSQG----LTK-KNQEVAKVLGTQIAEL--GKNLQ-LDRVVFDRGPFKYH--GIVSMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVQEAEEQLGFS---------------------------------QLKAGRCLKKVLNSAVAN----A- ELHE-NIKRENLSVTEVRVDAGPVYKRSKSKSRGGRSPILKRTSHLTVIVGEKQNIRVGDKVFILAGN------DK-GKE GKVLSLTED----KVV--VEGVNVRIKNIK----RS--QQ-NPK-GKRISIEAPIHISNVR-LTIAGE-----------P --AKLSVKV---TE--------QGREL---WQRRPDGTSQLY--MGQKGCPIGFRTG--VT-KKWRSLWYG------NKQ E--FGKFLIEDVRIRQFL--RKKPS-----CQGAAGFVVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRALVW LEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDA-GAVGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATACAETTYGIIGIKVWINGMTSDSIADLLTRIRNALMAEHLYVDV-EHSKMREAIVKILKHKGFVAHYL VKE----E---N----RKRAMRVFLQYS---DDR-------K---PVIHQLKRVSKPSRRVYVSAAKIPYVFGNMGISVL STSQGVMEGSLARSKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLVDILDPTGKTIDALKMLALPAGVDIKIKARKVKIGVVVSAKMEKTVVVRVERIFSHPQYL KVVRSSKKYYAHTEL---KVSEGDKVKIQETRPLSKLKRWRVIEHVGVV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRAMNI---EEKKT----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRIFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_pneumoniae_CWL029 Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTTRGELRGTKSKRSLRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGAKQL---- YRVVDFK-R--NK-DGITAKVVTVEYDPNRSAYIALLSYE-DGEKRYILAPKGIQRGDVVVSGE-G-SP-FKPGCCMTLK SIPLGLSVHNIEMRPSSGGKLVRSAGLAAQVIAK--SPGYVTLKMPSGEFRMLNEGCRATIGEVSNADHNLRVDGKAGRR -RWM-----GVR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKNK-SN-K-WIVKDR --------------------------------FMRSHIS-VMGKKEGMIHIFD-KDGS---------LVACSVIRVEPNV VTQIK----TKE----S--DGY--FSLQIGAEEMNAPAHT--IVSK----------PKLGHLK----------------- ---AG-GRVFRFLKEVRG------SEEALNGV-----SL---GD-AFGL--E-V-FEDVSSVDVRGISKGKGFQGVMKKF GFRG-GPGSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGAENVTVKNLEVIKVDLEKK---------------- ----------VLLVKGA-IPGARGSIVIVK-MVLLSKFD-FSGNKI-GEVEVADSLF-----ADEGDGLQLIKDYIVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------KQKGTGNAR--------QGC---LA-SP----QF---- RGGGIVFGPK-PKFNQHVRINRKERKAAIRLLLAQKIQTN----------------K-LTVVDDTVFVDALT-A------ --PKTQLFIDHLDHVEKNE---NLRLSLRNLTAVKGF---------------VYGININGYDLASAHN----IVISKKAL QELVSRLKKFYTEEI----RKSLFEKFGYANKMQIPVLKKIVLSMGLA-EAAKDKNLFQAHLEELTMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSN-KG-DGRGCYSVGLDDQQIFPEIN-----LDRV KRTQGLNITWVTT-----------------------AQTDDECTTLLELMGLRFMSRKA-R--EPILLPQGVEVS-I--- -Q-D--D-KIIVKGPKGSLTQKS-VKE----VEITLKD-NS--IFV---HAAP--HVVDRPS-CMQGLYWALISNMVQGV HLGFEKRLEMIGVGF--RASVQG-AF--LDLS--IGVSHPTKIPI-P-S-TLQVSVE--K-NTLISVKG-LDKQLVGEFA ASIRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPN-S-------SIKKGDVIKAVIVRTRRHITRKDGSTLKFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFIKISSLAPEVIIK-L--ESLFDISER-KRRKKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTGRLITLDALKAK-KAIAVK---------VIL--KGD-L-E-K-TFVWQD TAVVLSQGVQNLLGIT-----K---QQK--GQF---AGLS-KGATFVDFG----------EYAMQTL--ERGWVTSRQIE ACRVAINRYL------KRRGKVWIRIFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIKTRF-VKSLMKRRRALRVRKVL---KGSPTKPRLSVVKTNKHIYVQLIDD---S--IGKTL ASVSTL-SKLN-KSQG----LTK-KNQEVAKVLGTQIAEL--GKNLQ-LDRVVFDRGPFKYH--GIVSMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVQEAEEQLGFS---------------------------------QLKAGRCLKKVLNSAVAN----A- ELHE-NIKRENLSVTEVRVDAGPVYKRSKSKSRGGRSPILKRTSHLTVIVGEKQNIRVGDKVFILAGN------DK-GKE GKVLSLTED----KVV--VEGVNVRIKNIK----RS--QQ-NPK-GKRISIEAPIHISNVR-LTIAGE-----------P --AKLSVKV---TE--------QGREL---WQRRPDGTSQLY--MGQKGCPIGFRTG--VT-KRWRSLWYG------NKQ E--FGKFLIEDVRIRQFL--RKKPS-----CQGAAGFVVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRALVW LEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDA-GAVGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATACAETTYGIIGIKVWINGMTSDSIADLLTRIRNALMAEHLYVDV-EHSKMREAIVKILKHKGFVAHYL VKE----E---N----RKRAMRVFLQYS---DDR-------K---PVIHQLKRVSKPSRRVYVSAAKIPYVFGNMGISVL STSQGVMEGSLARSKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLVDILDPTGKTIDALKMLALPAGVDIKIKARKVKIGVVVSAKMEKTVVVRVERIFSHPQYL KVVRSSKKYYAHTEL---KVSEGDKVKIQETRPLSKLKRWRVIEHVGVV------------------------------- -MGRSL-RKGPFVDH-HLLKKVRAMNI---EEKKT----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRIFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_pneumoniae_J138 Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTTRGELRGTKSKRSLRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGAKQL---- YRVVDFK-R--NK-DGITAKVVTVEYDPNRSAYIALLSYE-DGEKRYILAPKGIQRGDVVVSGE-G-SP-FKPGCCMTLK SIPLGLSVHNIEMRPSSGGKLVRSAGLAAQVIAK--SPGYVTLKMPSGEFRMLNEGCRATIGEVSNADHNLRVDGKAGRR -RWM-----GVR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKNK-SN-K-WIVKDR --------------------------------FMRSHIS-VMGKKEGMIHIFD-KDGS---------LVACSVIRVEPNV VTQIK----TKE----S--DGY--FSLQIGAEEMNAPAHT--IVSK----------PKLGHLK----------------- ---AG-GRVFRFLKEVRG------SEEALNGV-----SL---GD-AFGL--E-V-FEDVSSVDVRGISKGKGFQGVMKKF GFRG-GPGSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGAENVTVKNLEVIKVDLEKK---------------- ----------VLLVKGA-IPGARGSIVIVK-MVLLSKFD-FSGNKI-GEVEVADSLF-----ADEGDGLQLIKDYIVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------KQKGTGNAR--------QGC---LA-SP----QF---- RGGGIVFGPK-PKFNQHVRINRKERKAAIRLLLAQKIQTN----------------K-LTVVDDTVFVDALT-A------ --PKTQLFIDHLDHVEKNE---NLRLSLRNLTAVKGF---------------VYGININGYDLASAHN----IVISKKAL QELVSRLKKFYTEEI----RKSLFEKFGYANKMQIPVLKKIVLSMGLA-EAAKDKNLFQAHLEELTMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSN-KG-DGRGCYSVGLDDQQIFPEIN-----LDRV KRTQGLNITWVTT-----------------------AQTDDECTTLLELMGLRFMSRKA-R--EPILLPQGVEVS-I--- -Q-D--D-KIIVKGPKGSLTQKS-VKE----VEITLKD-NS--IFV---HAAP--HVVDRPS-CMQGLYWALISNMVQGV HLGFEKRLEMIGVGF--RASVQG-AF--LDLS--IGVSHPTKIPI-P-S-TLQVSVE--K-NTLISVKG-LDKQLVGEFA ASIRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPN-S-------SIKKGDVIKAEIVRTRRHITRKDGSTLKFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFIKISSLAPEVIIK-L--ESLFDISER-KRRKKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTGRLITLDALKAK-KAIAVK---------VIL--KGD-L-E-K-TFVWQD TAVVLSQGVQNLLGIT-----K---QQK--GQF---AGLS-KGATFVDFG----------EYAMQTL--ERGWVTSRQIE ACRVAINRYL------KRRGKVWIRIFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIKTRF-VKSLMKRRRALRVRKVL---KGSPTKPRLSVVKTNKHIYVQLIDD---S--IGKTL ASVSTL-SKLN-KSQG----LTK-KNQEVAKVLGTQIAEL--GKNLQ-LDRVVFDRGTFKYH--GIVSMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVQEAEEQLGFS---------------------------------QLKAGRCLKKVLNSAVAN----A- ELHE-NIKRENLSVTEVRVDAGPVYKRSKSKSRGGRSPILKRTSHLTVIVGEKQNIRVGDKVFILAGN------DK-GKE GKVLSLTED----KVV--VEGVNVRIKNIK----RS--QQ-NPK-GKRISIEAPIHISNVR-LTIAGE-----------P --AKLSVKV---TE--------QGREL---WQRRPDGTSQLY--MGQKGCPIGFRTG--VT-KKWRSLWYG------NKQ E--FGKFLIEDVRIRQFL--RKKPS-----CQGAAGFVVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRALVW LEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDA-GAVGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATACAETTYGIIGIKVWINGMTSDSIADLLTRIRNALMAEHLYVDV-EHSKMREAIVKILKHKGFVAHYL VKE----E---N----RKRAMRVFLQYS---DDR-------K---PVIHQLKRVSKPSRRVYVSAAKIPYVFGNMGISVL STSQGVMEGSLARSKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLVDILDPTGKTIDALKMLALPAGVDIKIKARKVKIGVVVSAKMEKTVVVRVERIFSHPQYL KVVRSSKKYYAHTEL---KVSEGDKVKIQETRPLSKLKRWRVIEHVGVV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRAMNI---EEKKT----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRIFKSHP------V---------KKG-------- >CHLAM_Chlamydophila_pneumoniae_TW-183 Concatenation of 2 sequences -MFKKFKPVTPGTRQLVLPAFDE-LTTRGELRGTKSKRSLRP-NKKLSFFKKSSGGRDNLGHISCRH-RGGGAKQL---- YRVVDFK-R--NK-DGITAKVVTVEYDPNRSAYIALLSYE-DGEKRYILAPKGIQRGDVVVSGE-G-SP-FKPGCCMTLK SIPLGLSVHNIEMRPSSGGKLVRSAGLAAQVIAK--SPGYVTLKMPSGEFRMLNEGCRATIGEVSNADHNLRVDGKAGRR -RWM-----GVR-P-TVRGTAMNPVDHPHGGGEGRH----NGYI-PRTP---WGKVTKGLKTR-DKNK-SN-K-WIVKDR --------------------------------FMRSHIS-VMGKKEGMIHIFD-KDGS---------LVACSVIRVEPNV VTQIK----TKE----S--DGY--FSLQIGAEEMNAPAHT--IVSK----------PKLGHLK----------------- ---AG-GRVFRFLKEVRG------SEEALNGV-----SL---GD-AFGL--E-V-FEDVSSVDVRGISKGKGFQGVMKKF GFRG-GPGSHGS-GFHRH-AGSIGMR-STPG-RCFPGSKRPSHMGAENVTVKNLEVIKVDLEKK---------------- ----------VLLVKGA-IPGARGSIVIVK-MVLLSKFD-FSGNKI-GEVEVADSLF-----ADEGDGLQLIKDYIVAIR ANKRQWSACTRNRSE--------VS-HSTKKPF---------KQKGTGNAR--------QGC---LA-SP----QF---- RGGGIVFGPK-PKFNQHVRINRKERKAAIRLLLAQKIQTN----------------K-LTVVDDTVFVDALT-A------ --PKTQLFIDHLDHVEKNE---NLRLSLRNLTAVKGF---------------VYGININGYDLASAHN----IVISKKAL QELVSRLKKFYTEEI----RKSLFEKFGYANKMQIPVLKKIVLSMGLA-EAAKDKNLFQAHLEELTMISGQKPLVTKARN SIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSN-KG-DGRGCYSVGLDDQQIFPEIN-----LDRV KRTQGLNITWVTT-----------------------AQTDDECTTLLELMGLRFMSRKA-R--EPILLPQGVEVS-I--- -Q-D--D-KIIVKGPKGSLTQKS-VKE----VEITLKD-NS--IFV---HAAP--HVVDRPS-CMQGLYWALISNMVQGV HLGFEKRLEMIGVGF--RASVQG-AF--LDLS--IGVSHPTKIPI-P-S-TLQVSVE--K-NTLISVKG-LDKQLVGEFA ASIRAKR------PPEPY---KGKGIRYENEYVRRKAGK----------MIQQESQLKVADNTGAKKVKCFKVLG-SRRR Y--ATVGDVIVCSVRDVEPN-S-------SIKKGDVIKAVIVRTRRHITRKDGSTLKFDTNSCVIID-DKGN-PKGTRIF GPVAREIR-DRGFIKISSLAPEVIIK-L--ESLFDISER-KRRKKLLG-RGPSSGH-GKTSGRGHKGDGSRSGYK-R--- -RFGY-E-GGGVPLYRRVPT-RG--FSHITTGRLITLDALKAK-KAIAVK---------VIL--KGD-L-E-K-TFVWQD TAVVLSQGVQNLLGIT-----K---QQK--GQF---AGLS-KGATFVDFG----------EYAMQTL--ERGWVTSRQIE ACRVAINRYL------KRRGKVWIRIFPDKSVTKKPAETRMGKGK---------GAPDHWVAVVRP-GRILFEV--AN-- VSKEDAQDALRRAAAKLGIKTRF-VKSLMKRRRALRVRKVL---KGSPTKPRLSVVKTNKHIYVQLIDD---S--IGKTL ASVSTL-SKLN-KSQG----LTK-KNQEVAKVLGTQIAEL--GKNLQ-LDRVVFDRGPFKYH--GIVSMVADGAREGGLQ F---------------------------------------------------------------M-FKATARYIRVQPRK ARLAAGLMRNLSVQEAEEQLGFS---------------------------------QLKAGRCLKKVLNSAVAN----A- ELHE-NIKRENLSVTEVRVDAGPVYKRSKSKSRGGRSPILKRTSHLTVIVGEKQNIRVGDKVFILAGN------DK-GKE GKVLSLTED----KVV--VEGVNVRIKNIK----RS--QQ-NPK-GKRISIEAPIHISNVR-LTIAGE-----------P --AKLSVKV---TE--------QGREL---WQRRPDGTSQLY--MGQKGCPIGFRTG--VT-KKWRSLWYG------NKQ E--FGKFLIEDVRIRQFL--RKKPS-----CQGAAGFVVRRMS-G-KIEVTIQTARPGLVIGKKGAEVDLLKEELRALVW LEIAEIKR---PELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDA-GAVGVKIQVSGRLAGAEIARSEWYKNGRVPL- -HTLRADIDYATACAETTYGIIGIKVWINGMTSDSIADLLTRIRNALMAEHLYVDV-EHSKMREAIVKILKHKGFVAHYL VKE----E---N----RKRAMRVFLQYS---DDR-------K---PVIHQLKRVSKPSRRVYVSAAKIPYVFGNMGISVL STSQGVMEGSLARSKNIGGELLCLVWQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVVGPIPLPTKREVYTVLRS PHVDKKSR-EQFEIRTHKRLVDILDPTGKTIDALKMLALPAGVDIKIKARKVKIGVVVSAKMEKTVVVRVERIFSHPQYL KVVRSSKKYYAHTEL---KVSEGDKVKIQETRPLSKLKRWRVIEHVGVV------------------------------- -MSRSL-RKGPFVDH-HLLKKVRAMNI---EEKKT----PIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSE-TMVGH KLGEFSPTRIFKSHP------V---------KKG-------- >CHLOFL_Anaerolinea_thermophila_UNI-1 Concatenation of 2 sequences MAVKVYKPVTPGLRGMTGYTFEE-ITKT------------KP-ERSLIVVRKKHAGRNHFGRVTVRH-QGGGNRQF---- IRLVDFK-R--DK-RGIPARVAAIEYDPNRTARIALLVYA-DGEKRYIVAPLGLKVGDTVLAGK-D-AE-IRPGNSLPIA NIPVGTMIHNIELKEGRGGQLVRAAGAAAQLLAK--EGDYAQVRLPSGEVRLVRQTCYATIGQVGNLDHSNVKLGKAGRK -RHM-----GIR-P-TVRGTAMSPRDHPHGGGEGRQ-P--VGMPGPKSP---WGKPTRGYKTR-RNKQ-TD-K-YIVRRR --------------------------------MLK---G-LIGKKIGMTQIFD-ENGV---------AIPVTVIEAGPCY VTQVR----TPE----N--DGY--SAVQLGF-------EE--VLTG----------GELGHLK----------------- ---RNNLPPLRFLREFRV---------KNPEV-----KE---GD-KVTV--E-C-FAVGERVDVVGTSKGKGFQGGVKRY HFRG-GPKTHGQSDRHRA-PGSRSSG-TTPG-RVYKGSRGPGHMGNDRVTAQGLKVVLVDTERN---------------- ----------LIGVKGS-VPGAKGGLVVIK--MLVDVVN-MQGQKV-SSVELPESIF----EA-PI-YIDLMHQAYVRQM ANARLGTHDTKTRNE--------VS-GGGRKPW---------RQKGTGRAR--------QGS---TR-SP----VW---- AKGAKVHTPH-P-RSYVQLMPRKMRRAALRSALSVKAAEN----------------A-IVVVDQL----TLP-E------ --AKTRLVL--IPEKE--A-YEGVIRSTRNLPDAK-I---------------LLANYLNIRDLLMFDK----VVMPLAAL DVISNRLKEYYQKEV----VPALMKSLGLDNVMQVPKIQKVVVNIGLG-EALDNPKALEAASADLMAITGQKPVITKARK SIAAFKLREGRAIGAKVTLRGERMWSFLDRLMNVALPRVRDFRGVSR-DAFDGRGNYTLGLREQLIFPEIE-----YDKI DKIRGMEITIVTT-----------------------AKSDDHAAALLEMLGMPFMSRIG-R--LPVVIPSGVQVG-V--- -D-G--L-SVTVKGPRGTLARTF-APG----VQITLEG-NQ--VQV---TR-E--SDEPRIK-ALHGTTRALIQNMVTGV STGFTKVLEIEGVGY--RASMEG-KN--LVLN--VGYSPPVVVEP-P-A-GITFEVEERT-R-QIRVIG-ADAEQVGQIA ADIRKIR------PPEPY---KGKGIHYLGEKIRRKAGK----------MIQQETRLKVADNTGARELLVIHIMG-STRK Y--GEVGDIVVATVKSAAPQ-G-------AVKKSEIVKAVIVRCAKEWRREDGSTIRFDDNAAVILD-SSGQNPRGTRIF GPVARELR-EKGFMKIVSLAPEVLMK-L--HDLFPNEGA-KKKHKRKG-IGIAAGQ-GKTAGRGTKGEGARSGQG-G--- -KLYR-Q-GGNLPFYRRLPFMRGEGFTPVNVEQLVTPELLAQA-GMLHVV---------ILG--RGE-L-T-R-A-LTV- QAQRVTKGARAKIEAAGGKV-K---QQR--GNM---RGKA-LRGAEIAFG----------EYALQAL--EPGWVSARQIE AARRAIVREM------RRRGKIWIRIFPDKPYTHRPPETRMGKGK---------GNVEYWVAVVRP-GRIMFEV--GG-- LPEEVAKEALRQASYKFSIKTKV-IRAEGRLHRHRRVRMKV---QGTPERPRLSVYRSLAEIYAQVIDD---Q--AGHTL AAASSI-DHEL-REKT----AGL-NKTEQAKLVGKLVAER--ALAKG-IKQVVFDRGGFRYI--GRVKALADAAREAGLD F-------------------------------------------------------------ATD-IRAQLKFAETSAQK ARLVVDLVRGKPVVEASNILRFT---------------------------------PKKAARIINKVLDSAIAN----A- EENF-GVSRDNLYIHEIAADEGPTRKWRRFGARGRFKPILRRTSHITIVLREKVKIHKGDTVEVISGRRE----DK-GKR GEVIRVLPDEG--RVV--VQGVNLRTKHQR----QV-QAQ-GRTNPGLVKFEAPIHISNVM-LVCPKC-------GK--A --TRVGINR---QA--------EKAVR---VCKKCQ---AVI--MGRKVNPVGFRLV--VN-KAWESRWFA------DGK E--YTQNLQQDFQIRKLV--REIAE-----NAGVSRVEVERFP-G-KVRVIVFTAKPGILIGRKGESVKKLRQDLEALID LEIKEIKN---PDTDALLVAENLASQIERRVSYRRAMKRALQQAMRQ-GAKGIKVEVQGRLSGAEMSRSVWLREGRVPL- -QTLRADIDFARAEALTTYGRIGVKVWVYMSVNDPIADMLTRIRNGIMAGHAMVAM-PSSKIKVEIARILKEEGYIEDYE VAE-EAEN---S----ARKVLRLKLKYV---GER-------RQRKPVITGLERVSKPGRRIYTPKSEIPWVLSGMGIAIL STPKGVMTGQQARKLGVGGEILCKVWMAKQRIRIRLKAFDHRVLDQSAKRIVETAERSGARVVGPVPLPTKIERYTVRRS TFIDKDSH-EHFEIRTHNRLIDVIDPDAKTIDMLMRLNLPAGVDIEIKIRRRMTGLVTSNKMMKTVVVQITRTFQHPLYK KVVHSIKKVKAHDEL--G-CEVGDVVQIVESRPLSAQKRWVVEKIVRKS------------------------------- -MSRSL-KKGPYVDP-KLLKKIELMNT---RGEKK----VIRTWSRASVIFPQMVGHTIAVHDGRRHVPIYITE-NMVGH RLGEFAPTRLFRGHV------A---EKSSGAKGK-----GGK >CHLOFL_Caldilinea_aerophila_DSM_14535 Concatenation of 2 sequences MAIKIYRPTSPGRRGMSVSTFEE-ITKT------------EP-ERSLLAPLRKKSGRNNRGVITVRH-RGGGHKRR---- YRIIDFR-R--DK-VGVPARVESIEYDPNRSARIALVVYN-DGERRYILAPQGLNVGDTVMSGP-G-AD-IRPGNALPIR NIPLGTMVHNIELYPGRGGQLVRSAGLGAQVLAK--EGKMAQVRLPSGEVRYVHMDCFATIGVVSNPDHANINLGKAGRK -RWL-----GIR-P-TTRGVAMDPGSHPHGGGEGRS-P--IGMKAPKTP---WGKPALGKKTR-RNKR-TA-K-YIVRRG -----------------------------------------------MTQLFD-KSGA---------VIPVTIIEAGPCY VTQVK----TEE----T--DGY--NAVQLGY-------EI--ALTK----------GQRGHLK----------------- ---AG-VPMLRRLREFRY--------DETPAL-----SV---GD-VVKA--D-I-FAEGDLVDVVGVSKGRGFAGAVKRH GFAG-GPKTHGQSDRHRA-TGSRGAG-TTPG-HTFPGTRAPGQYGAARTTVQNLKVALVDPERN---------------- ----------LIAVRGA-IPGPRGSLVIVR----------MNGQQV-GEVELSDAVF----AA-PI-HTAVMHQALMRQL ANARLGTHDTKTRSE--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- VGGGIVFGPT-P-RKYTKALPKKMQRMALRSALSVKAAEG----------------Q-IVVIDRV----AID-E------ --PKTKLLV--MNEKS--V---PVWKSVRNLPQVK-S---------------LLTGYLNIRDLLGYDV----LLLTRDAV DFIEPRLKVRYREEV----VPALVKEFNYRSVMQAPRIEKISVNIGLG-EALQNSKALEFAANDLATITGQKPVITKARR SIAAFKLREGMPIGLKVTLRGDRMWDFLDRLINVVLPRQRDFQGVSP-DSFDGRGNYSLGLREQLVFPEIN-----YDKI DKIRGMEITIVTT-----------------------AKTDEEARRLLALLDMPF---------MPIALPPKVTVS-V--- -DKG--N-LVTVSGPKGTLKQQF--DP-D--MIIQVED-GH--VRI---SR-P--SDQRRHR-AQHGLTRALLANMVQGV TVGFTRRLEIRGVGY--RAEKRG-SN--LVLS--VGKSHPVEFAP-PTP-DVVFEVDKDG-R-GFTISG-IDKATVGELA AKIRGTR------PPEPY---QGKGIRYQGEYVRQKAGK----------MIQQESRLKVADNTGAKELLTIRVKG-STRR Y--GSVGDIIVATVKSASPT-G-------SVKKGDVVRAVIVRTTRPIRRPDGSYIRFDENAAVIID-DNKN-PRGTRIF GPVARELR-EGGFMKIVSLAPEVLMK-L--HDLRPAEGS-TKKRKRVG-RGTGSGK-GKTSGRGQKGQNARSGGS-V--- -RLNF-E-GGQLPLTKRLPKLRG--FNNVNLDQLVSQETLARV-GLLGVV---------VLA--RGE-V-T-K-P-LTV- RVQRISAAARQKIEAAGGTV-----MQR--GRL---KGKA-YRGNTVAFG----------AYGLQAT--EGHYVTSRQIE AARRAIVRYV------RRGGKIWIRIFPDKPVTKRAAETRMGSGK---------GSVDHWVAPVRP-GRVIMEI--AG-- VREDQAREAFRLAAAKLPMKTQF-IRAAARQRRHARVRVKV---HGTPERPRLNVFRSLEHIYAQVIDD---V--NGVTL ASASTI-DREL-RDQV----ASL-PKLEQAKMVGKMVAER--AKAKG-VTRVVFDRGGYPYH--GRVKALAESSREAGLE F---------------------------------------------------------------------MKYTGISAQK TRLVINEIRGRRAEEALTILSYM---------------------------------PQSAARVVSKTVKSALAN----A- VENF-GYDAKDMVITKIYADDAPIRRRFG--ARGRFKPWQRRSSHITVVLEEKVKIVKGDTVEIIAGD------DK-GHR GEVQRVIRKKN--KVI--VAGANMVTRHQR----PT-GRV-RTQ-TGRITREAPIHISNVM-LVGSD--------GK--P --TRVGYEV---AK--------DGKER---IDRKTG---APL--MGRKVHPIGFRLG--II-KEHKSRWFA------TGR Q--YTDQVTEDRQIRALV--YERQATKN--KAGISNIDIERQP-N-QVHIIIDTARPGVIIGRKGASVNQLRQQLQELVK IDVREITK---PELDARLVAESIAEQIERRVSWKRAMKQAAQKTMRA-GAQGIMITVSGRLGGSDMGRVDSLREGRIPR- -HTLRADIDYGTAEANTTFGVIGVKVWIY----------------------------------MGIAQILLQEGFIEGYT VTD----E---K----PQPNLIVRLKYT---PQG-------R---SVIRGLERVSRPGRRYYAGFKDIPWVRSGLGINII STPKGLMTGRRARRERLGGEILCNIWMAKQKIRIKLKAYDHRVLDASVRQIVDAAEQTGAQVVGPVPLPTTIEKFTVMRS PFIDKDSR-EQFEIRTHKRLIDVIDPGSKTIENLTRLNLPAGVDIEIKL------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------ >CHLOFL_Chloroflexus_aggregans_DSM_9485 Concatenation of 2 sequences MGIRIYKPTSAGRRNMSVSTFEE-ITKK------------RP-EPGLIEPLRKKAGRNNQGRITVRH-RGGGHKRF---- YRIIDFK-R--DK-FGIPAKVQAIEYDPNRSARIALLAYV-DGEKRYIIAPLGLKVGDTVMSGP-N-AE-IRVGNALPLG AIPLGTQIHNIELEIGRGGVLVRAAGTAAQLMAK--EGDYATIRMPSGEVRMIHLRCMATIGQVGNVDHQNIRLGKAGRS -RWL-----GRR-P-RVRGAAMNPRDHPHGGGEGRA-P--RGMSTPKTK---WGKPARGVKTR-HNPR-FD-R-FIIRRR --------------------------------MIH---G-LLGRKIGMMQYFT-KEGR---------AIPVTVIAAGPCI VTQIR----TPE----R--DGY--SAVQLGY-------EE--VLTK----------PQQGHLA----------------- ---SG-GKMLRYLREFSA--------DDPLAH-----KP---GE-VVTV--E-L-FKPGQKVDISGTSKGRGFAGVVKRH GFRG-GPKTHGQSDRHRA-PGSIGAG-TTPG-RVWKGQRMAGRMGGDRVTIQNLEVVEVLPEQN---------------- ----------LLLVKGS-VPGARNGLLQIR--MQATLYN-QAGEQV-GSIEVSDYIF----GI-EP-NVPVMHQYVVMQN ANARLGTHNTRGRGE--------VK-GSTRKLY---------RQKGTGRAR--------QGS---IR-AP----HH---- KGGGVAHGPH-P-RSYRVSMPRKMRRLGVRSALSVKFAAN----------------Q-IRFIDEL----TFP-Q------ --PRTKLVV--IDSKS--PANENLRRSANNLPKVK-T---------------LLAHYLNVRDLLVYDH----IIMPKAAV QVVEVRLREKYYKEV----VPALMEEFKFKSIMQVPRLVKIVVNVGVG-EAVQNAKAIEAAVNDVAAITGQKPVVTRAKK SVASFKLRAGMPIGVMVTLRGDRMYDFLDRLCSLALPRIRDFRGVSR-SSFDGRGNYSIGLKEQIVFPDID-----YDKI DKIRGLEVAIVTS-----------------------APNDEQAYSLLKRLGMPFMSRIG-K--RPITVPKGVQVT-I--- ---G-EQNLVTVKGPKGTLTQKL--HP-D--MIIKQEG-DV--ITV---QR-P--SDEKLHR-SLHGLTRTLINNMIVGV TQGWQRALEINGVGY--RAQLEG-KT--LVLN--LGFSHPVRIEP-P-P-NISYIVN--D-PLSLTVVG-IDKQQVGEEA ARIRSLR------PPEPY---KGKGIKYLEEKIRRKAGK----------MIQPQTRLKVADNTGAKEIMCIRVLG-SRVR Y--GRVGDIIVASVKEATPG-G-------QVKKGDVVKAVIIRTAKEYGRPDGSHIRFDDNAAVLIG-KENN-PRGTRIF GPVARELR-EKQFMRIVSLAPEVLMK-L--HDLRPAEGS-HRKRKRIG-RGHGSGK-VKTGGKGMMGQKARSGPG-P--- -YRTF-E-GGQNRLVKRMPFKRG--FTNVNVGSLVTPETLLAR-RLVRVK---------ILG--DGE-L-N-Q-P-LVI- KAHKFSASARQKIEAAGGKA-K---MQK--GRS---HGLS-YRGNSVAFG----------EYGLMAL--EPSWISSRQIE AARRAITNYV------KRGGKVWIRIFPDKPITRKPAETRMGGGK---------GSVDHWVAVVKP-GRIMFEL--AG-- VREDIAHEALRRAAQKLPVKCKV-IPRELRLRRHNRIRKRV---SGTPERPRLNVFRSHAHIYAQVIDD---T--VGHTL VAASTI-EKGW-SGS-----PEL-TKTQEAALVGKLIAER--ALQAG-ITKVVFDRGGYKYH--GRVKALAEAAREAGLN F--------------------------------------------------------------ME-AKAVTRYVRISPLK VRLVMDVVRGMPVDRALATLRYM---------------------------------PQKAAREVARTLKSAIAN----A- EHNF-DMNRDELYIKTIYADQGPVLKRFMPRARGMANRIRKPTTHITVVVAD-MHVKTGDEVLVIAGK------DK-GRR GKIKRALPAVN--RVV--VEGLNIVKRHQK----PR--GP-GRP-GGIVEMEAPIHVSNVM-LICPSC-------GR--A --SRTGKRF---LE--------ETKVR---YCKACD---AII--MGRKVHPIGFRLG--YI-KDWQSKWFA------E-G E-TYTKQLHEDIELRKLI--SKELQ-----SAGVSRIEIERSA-N-KIEISVYTAKPGIVIGKRGTNVDTLKSALEKKIK LNIKEISQ---PELDAQLVAESIGEQITKRVSYKRAMKQAVQRAMRL-GAQGVKIRCSGRLAGAEMARVHEEAEGRVPR- -HTLRADIDYAQVHAHTTYGRIGVKVWIYMSVNDPIGDMLTRIRNACMARHTTVTM-PASKMKIAIADILKREGFIRDYT VID---DG---K----PYKTISITLKYM---PDR-------R---PAITGLRRVSKPGLRVYTKRADIPRVRGGLGLSIL STPKGVLADHEAWRARVGGEVLCYVWMAKQKVRIRLKAYDHKILDQSARQIVEAAERTGALVAGPVPLPTKIERYSVIRS GFIDKDSQ-EQFEIRTHKRLIDVLDPSQQTINALMKLNLPAGVDIEIKLKTTKVGRVVSDKMDKTVVVKVDYLKPHPLYR KIIRRSKKFHAHDEE--NTCKVGDVVRIEETRPLSRTKRWRVVEIIKRG------------------------------- -MSRSS-KKGPYVDI-KLLDKIEAMNK---ANEKR----AIRTWSRDSTIFPQMIGHTILVHDGRRHVPVYITE-NMVGH KLGEFAPTRFFRGHG------GKKADK----RGK------VK >CHLOFL_Chloroflexus_aurantiacus_J-10-fl Concatenation of 2 sequences MGVRIYKPTSAGRRNMSVSTFEE-ITKK------------EP-EPRLIEPLRKKAGRNNQGRITVRH-RGGGHKRF---- YRIIDFK-R--NK-FGVPAKVQAIEYDPNRTARIALLAYA-DGEKRYIIAPLGLKVGDTVMSGP-D-AE-IRVGNALPLS AIPLGTQIHNIELEIGRGGVLVRSAGTAAQLMAK--EGDYAIVRMPSGEMRMIHLRCMATIGQVGNVDHQNIRLGKAGRS -RWL-----GRR-P-RVRGAAMNPRDHPHGGGEGRA-P--RGMSTPKTK---WGKPARGVKTR-HNPR-FD-R-FIVRRR --------------------------------MIH---G-LLGRKIGMMQYFT-AQGM---------AIPVTVIAAGPCI VTQIR----TPE----R--DGY--SAVQLGY-------EE--VLTK----------PQQGHLA----------------- ---SG-GKMLRYLREFSA--------DDPQAH-----TP---GE-VVTV--E-L-FRPGQKVDISGTSKGRGFAGVVKRH GFRG-GPKTHGQSDRHRA-PGSIGAG-TTPG-RVWKGQRMAGRMGGTRVTIQNLEVVEVLPEQN---------------- ----------LLLVKGS-VPGARNGLLQIR--MQATLYN-QAGEQV-GAIEVSDYIF----GI-EP-NVAVMHQYVVMQN ANARLGTHNTRGRGE--------VK-GSTRKLY---------RQKGTGRAR--------QGS---IR-AP----HH---- KGGGVAHGPH-P-RSYRLAMPRKMRRLGVRSALSAKFAAD----------------Q-IRFVDEL----TFE-R------ --PRTKLVV--IDSKS--PANENLRRSANNLPQVK-T---------------LLAHYLNVRDLLVYDH----IVMPKAAV EVVEVRLREKYQKEV----VPALMEEFKFKSIMQVPRLVKIVVNVGVG-EAVQNAKAIEAAVNDLATITGQKPVVTRAKK SVASFKLRAGMPIGAMVTLRGDRMYDFLDRLCSLALPRIRDFRGVSR-SSFDGRGNYSLGLREQIVFPDID-----YDKI DKIRGLEVAIVTS-----------------------APNDEQAYALLKRLGMPFMSRIG-K--RPITVPKGVQVT-I--- ---GEQN-LVTVKGPKGTLSQQL--HP-E--MIIRQEG-DV--ITV---QR-P--SDGKLHR-ALHGLTRTLIHNMVVGV TQGWQRALEINGVGY--RAQLEG-KT--LVLN--LGFSHPVRIEP-P-P-NISYIVN--D-PLALTVVG-IDKQQVGEEA ARIRSLR------PPEPY---KGKGIKYAEEKIRRKAGK----------MIQPQTRLKVADNTGAKEIMCIRVLG-SRVR Y--GRVGDIIVASVKVATPG-G-------QVKKGDVVKAVIIRTAKEYGRPDGSHIRFDDNAAVLIG-KENN-PRGTRIF GPVARELR-EKQFMRIVSLAPEVLMK-L--HDLRPAEGA-HRKRKRIG-RGHGSGK-GKTGGKGMMGQKARSGPG-P--- -YRTF-E-GGQNRLVKRMPFKRG--FVNVNVGSLVTPETLLAR-RLVRVK---------ILG--DGE-L-T-Q-P-LVI- KAHKFSASARQKIEAAGGKA-K---MQK--GRS---PGLS-YRGNNVVFG----------EYGLMAL--EPSWISSRQIE AARRAITNYV------KRGGKVWIRIFPDKPVTRKPAETRMGGGK---------GSVDHWVAVVKP-GRIMFEL--AG-- VREDVAHEALRRAAQKLPIKCKV-IPRELRLRRHNRIRKRV---FGTPERPRLNVFRSHVHIYAQVIDD---T--VGHTL VAASTN-EKGW-SGS-----PEL-TKTQEAALVGKLIAER--ALQAG-ITKVVFDRGGYKYH--GRVKALAEAAREAGLN F--------------------------------------------------------------ME-AKAVTRYVRISPLK VRLVMDVVRGMNVDRALATLRYM---------------------------------PQKAAREVARTIKSAAAN----A- EHNF-DMDRESLYIKTIYADQGPVLKRIMPRARGMANRIRKPTTHITVVVAD-MHVKTGDEVLVIAGK------DK-GRR GKIKRALPAVN--RVV--VEGINIVKRHQK----PR--GP-GRP-GGIIEMEAPLHASNVM-LICPSC-------GR--A --SRTGKRF---LE--------ETKVR---YCKACD---AVI--MGRKVHPIGFRLG--YI-KDWQSKWFA------EGE E--YTRQLHEDIELRKLI--SKELQ-----SAGVSRIEIERSA-N-KIEISVYTAKPGIVIGKRGTNVDTLKSALERKIK LNIKEIHQ---PELDAQLVAESIGEQITRRVSYKRAMKQAVQRAMRL-GAQGVKVRCSGRLGGAEMSRVHEEAEGRVPR- -HTLRADIDYAQVHAHTTYGRIGVKVWIYMSVNDPIGDMLTRIRNACMARHTTVSM-PASNMKEAIARILKREGFIRDYA VID----D-G-K----SHKTITITLKYL---PDR-------R---PAITGLRRVSKPGLRIYTKRTDIPRVRGGLGLCIL STPKGVLADHEAWRERVGGEVLCYVWMAKQKVRIRLKAYDHKILDQSARQIVEAAERTGALVAGPVPLPTKIERYSVIRS GFIDKDSQ-EQFEIRTHKRLIDVLDPSQQTINALMKLNLPAGVDIEIKLKTTKVGRVVSDKMNKTVVVAVDYLKPHPLYR KIIRRTKKFHAHDEE--NVCKVGDTVRIEETRPLSRTKRWRVVEILKRG------------------------------- -----------------MLDKIEAMNK---ANEKR----VIRTWSRDSTIFPQMIGHTIAVHDGRRHVPVYITE-NMVGH KLGEFAPTRFFRGHG------GKKADK----RGK------VK >CHLOFL_Chloroflexus_sp_Y-400-fl Concatenation of 2 sequences MGVRIYKPTSAGRRNMSVSTFEE-ITKK------------EP-EPRLIEPLRKKAGRNNQGRITVRH-RGGGHKRF---- YRIIDFK-R--NK-FGVPAKVQAIEYDPNRTARIALLAYA-DGEKRYIIAPLGLKVGDTVMSGP-D-AE-IRVGNALPLS AIPLGTQIHNIELEIGRGGVLVRSAGTAAQLMAK--EGDYAIVRMPSGEMRMIHLRCMATIGQVGNVDHQNIRLGKAGRS -RWL-----GRR-P-RVRGAAMNPRDHPHGGGEGRA-P--RGMSTPKTK---WGKPARGVKTR-HNPR-FD-R-FIVRRR --------------------------------MIH---G-LLGRKIGMMQYFT-AQGM---------AIPVTVIAAGPCI VTQIR----TPE----R--DGY--SAVQLGY-------EE--VLTK----------PQQGHLA----------------- ---SG-GKMLRYLREFSA--------DDPQAH-----TP---GE-VVTV--E-L-FRPGQKVDISGTSKGRGFAGVVKRH GFRG-GPKTHGQSDRHRA-PGSIGAG-TTPG-RVWKGQRMAGRMGGTRVTIQNLEVVEVLPEQN---------------- ----------LLLVKGS-VPGARNGLLQIR--MQATLYN-QAGEQV-GAIEVSDYIF----GI-EP-NVAVMHQYVVMQN ANARLGTHNTRGRGE--------VK-GSTRKLY---------RQKGTGRAR--------QGS---IR-AP----HH---- KGGGVAHGPH-P-RSYRLAMPRKMRRLGVRSALSAKFAAD----------------Q-IRFVDEL----TFE-R------ --PRTKLVV--IDSKS--PANENLRRSANNLPQVK-T---------------LLAHYLNVRDLLVYDH----IVMPKAAV EVVEVRLREKYQKEV----VPALMEEFKFKSIMQVPRLVKIVVNVGVG-EAVQNAKAIEAAVNDLATITGQKPVVTRAKK SVASFKLRAGMPIGAMVTLRGDRMYDFLDRLCSLALPRIRDFRGVSR-SSFDGRGNYSLGLREQIVFPDID-----YDKI DKIRGLEVAIVTS-----------------------APNDEQAYALLKRLGMPFMSRIG-K--RPITVPKGVQVT-I--- ---GEQN-LVTVKGPKGTLSQQL--HP-E--MIIRQEG-DV--ITV---QR-P--SDGKLHR-ALHGLTRTLIHNMVVGV TQGWQRALEINGVGY--RAQLEG-KT--LVLN--LGFSHPVRIEP-P-P-NISYIVN--D-PLALTVVG-IDKQQVGEEA ARIRSLR------PPEPY---KGKGIKYAEEKIRRKAGK----------MIQPQTRLKVADNTGAKEIMCIRVLG-SRVR Y--GRVGDIIVASVKVATPG-G-------QVKKGDVVKAVIIRTAKEYGRPDGSHIRFDDNAAVLIG-KENN-PRGTRIF GPVARELR-EKQFMRIVSLAPEVLMK-L--HDLRPAEGA-HRKRKRIG-RGHGSGK-GKTGGKGMMGQKARSGPG-P--- -YRTF-E-GGQNRLVKRMPFKRG--FVNVNVGSLVTPETLLAR-RLVRVK---------ILG--DGE-L-T-Q-P-LVI- KAHKFSASARQKIEAAGGKA-K---MQK--GRS---PGLS-YRGNNVVFG----------EYGLMAL--EPSWISSRQIE AARRAITNYV------KRGGKVWIRIFPDKPVTRKPAETRMGGGK---------GSVDHWVAVVKP-GRIMFEL--AG-- VREDVAHEALRRAAQKLPIKCKV-IPRELRLRRHNRIRKRV---FGTPERPRLNVFRSHVHIYAQVIDD---T--VGHTL VAASTN-EKGW-SGS-----PEL-TKTQEAALVGKLIAER--ALQAG-ITKVVFDRGGYKYH--GRVKALAEAAREAGLN F--------------------------------------------------------------ME-AKAVTRYVRISPLK VRLVMDVVRGMNVDRALATLRYM---------------------------------PQKAAREVARTIKSAAAN----A- EHNF-DMDRESLYIKTIYADQGPVLKRIMPRARGMANRIRKPTTHITVVVAD-MHVKTGDEVLVIAGK------DK-GRR GKIKRALPAVN--RVV--VEGINIVKRHQK----PR--GP-GRP-GGIIEMEAPLHASNVM-LICPSC-------GR--A --SRTGKRF---LE--------ETKVR---YCKACD---AVI--MGRKVHPIGFRLG--YI-KDWQSKWFA------EGE E--YTRQLHEDIELRKLI--SKELQ-----SAGVSRIEIERSA-N-KIEISVYTAKPGIVIGKRGTNVDTLKSALERKIK LNIKEIHQ---PELDAQLVAESIGEQITRRVSYKRAMKQAVQRAMRL-GAQGVKVRCSGRLGGAEMSRVHEEAEGRVPR- -HTLRADIDYAQVHAHTTYGRIGVKVWIYMSVNDPIGDMLTRIRNACMARHTTVSM-PASNMKEAIARILKREGFIRDYA VID----D---GK---SHKTITITLKYL---PDR-------R---PAITGLRRVSKPGLRIYTKRTDIPRVRGGLGLCIL STPKGVLADHEAWRERVGGEVLCYVWMAKQKVRIRLKAYDHKILDQSARQIVEAAERTGALVAGPVPLPTKIERYSVIRS GFIDKDSQ-EQFEIRTHKRLIDVLDPSQQTINALMKLNLPAGVDIEIKLKTTKVGRVVSDKMNKTVVVAVDYLKPHPLYR KIIRRTKKFHAHDEE--NVCKVGDTVRIEETRPLSRTKRWRVVEILKRG------------------------------- -MSRSS-KKGPYVDI-KLLDKIEAMNK---ANEKR----VIRTWSRDSTIFPQMIGHTIAVHDGRRHVPVYITE-NMVGH KLGEFAPTRFFRGHG------GKKADK----RGK------VK >CHLOFL_Dehalococcoides_ethenogenes_195 Concatenation of 2 sequences MAIKIYRPTSPGRRHHSVSSFEE-ITKS------------RP-EKALLVSVKNDSGRNNQGRVTVRH-RGGGSKTQ---- IRVIDFK-R--NK-LDVPGRIAAIEYDPNRTARIALVFYT-DGEKRYILAPSDLKIGDVIMAGE-N-AE-PKSGNALPLS AIPTGTFIHNIELIKGRGGIMVRSAGAAAQLMAK--EGDYALVRLPSGEMRKVRSDCSATVGQIGNIEHGTLEIGKAGRN -RHL-----GWR-P-TVRGSAMSPNNHPHGGGECRS-P--IGMTGPKTP---WGKPALGYRTR-KAKY-SD-K-LIVKRR --------------------------------MIQ---G-IIGKKIGMTQIFQ-EDGK---------AQPVTLVEAGPCV VVQVK----TEK----Q--DGY--EAVQLGY-------GK---ITS----------AVKGQC------------------ ---RG-FGEFKVLREVDV--------DDIAAV-----NV---GD-QITV----SDFKDGEKIDASGVSRGRGFAGVVKRW HFAG-GPKTHGQSDRHRA-PGSISST-TTPG-RIYKGKRMAGHMGNDAVTIRNLVVLKTDAEKN---------------- ----------LLMVKGA-IPGGKNTIILIK--MEIPVYN-ASGEII-KNISISEDVF----GV-PF-NEALVHQAFVAQQ ANARQGTQSTKTRGE--------VQ-GSSRKIY---------RQKGTGNAR--------MGT---NR-SP----VR---- RHGGVAFGPR-P-RDFSKDLPKKMRRQAIRCVLSFKLESG----------------E-LKVVDQL----SFD-E------ --PKTRLIA--VDNPD--T---NFIKSARNIPAVK-T---------------TPANLLNISDMLRNKQ----LVMTEEAV RQVELKVEERYTNAV-----PELQKAFKYENIMQVPKLVKVVINTGVG-EAVSNSKALETAEADIVAIAGQHPVITRAKR SVANFKLRAGMPIGLKVTLRGQRMYDFLNKLFFITLPRVRDFQGVSN-TAFDEHGNYTLGFKDHSVFPEID-----FNKI EKPRGLEVCIVTT-----------------------ANTPEEGKKLLELLGMPFMSRIG-K--MPIKVPPGVTVD-I--- -K-G--N-DVTVKGPKGTLNRTF--RP-E--VTITRDG-DY--LVV----A-P-VGTDKAAR-SFFGLSRTLLDNMIVGV KDGFDKNLEIVGVGM--RADKDG-NN--IIFK--VGYSHTVTVAP-P-A-GITLSVD--G-TTKVKVSG-INKEEVSQMA AEIRSIR------KPDHY---MGKGIRYAGEYVRIKPGK----------MVQQYTRLNVADNTGAKKIMCINVLG-SRKL Q--AKVGDVIVAAVKKSSPD-A-------QAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILN-DKME-PKGTRIF GPVARELR-DKKFTKILSLAPEVLMR-L--NELSPAPGS-KKDRKRVG-RGDA-GR-GNYSGRGMKGQKARSGGA-T--- -RPGF-E-GGQLPIYLRLPRKRG--FFNVNIEQLVTPETMLAA-GLIRVK---------ILA--AGH-I-D-R-A-LEV- SAHKFSQAAKAQIEAAGGKV-K---VQR--GRR---DGAA-HKGNTVAFG----------EFALQSL--EAGWITARQIE ATRRAITRYI------RRGGQVWIRIFPDKPITKKPAETRQGGGK---------GAPEEWVAVVRR-GRIMFEI--GG-- VTPEAAKEAMRLASYKMPVKTRF-VAREARIVRHERLRKKV---SGTEARPRLCVFRSIENIYTQVIND---N--CGSTL VQASTK-DAEL-KAEL----DGK-TKTEQAVVIGNLIAKR--SLEAG-ISEVVFDRGGYKYH--GRVKALAEAARSGGLK F--------------------------------------------------------------ME-VKAIVKDTGYSALK VRLCVDMVRGKKVSEAITMLRFM---------------------------------TSPTAKVVSKVIKSAAAN----A- ENNF-QMNPADLKISQIYADEARMLKRMRPQARGRVSPILKRSSHITVVVAD-MRLKKNDNVLVIAGK------DK-GKT GKVRYAFPRTD--RVL--VEGVNMIKRHSR----AR--GQ-AKQ-AGIIEREAPLHVSNLM-LLCSKC-------NK--P --ARIGSRE---LA--------DGSVR---YCKSCN---EVI--MGRKVHPIGFRLG--II-KDWSAKWHA------SDK G--FAECLTEDLKLRKAI--AKKYV-----DAAISQVDIERQS-N-KVTVSVRTARPGIVIGRGGQRVDEMRHFLEELVQ LNIVEISQ---AELDAFLVARSVAEQIERRVAYRRAMKQAIFRSMQA-GAKGIKVCASGRLGGVEIARREVMHEGRVPL- -HTLRADIDYGCTRAHTALGDIGIKVWVY-MISDPIADMLTRIRNGVMAKHEVVIM-PASRMKQYLAKVMKQEGFIAGYE VIG----A---K----PKRQLKIVLRYD---EGG-------A---SFVSGLERISKPGLRVYVQRGEIPRVYGGLGIAIV STSKGVMTGSQAWRQGLGGELLCKVWMTKQKIRIKLKGFDHKILDQSALQIVEALERTGATISGPVPLPTRIQRYSVIRS SFIDKDSQ-EQFEIRTHKRLIDIVETTSKTIDALTNLNLPAGVSIDIKLNKTRIGHVISDRMEKTIVVGIDVAKRHPLYK KTYRRTMKYLVHDEK--NEAKIGDMIEIVKCRPISKGKYWRLNRIITKG------------------------------- -MSRSV-KKGPALCP-KLMKKVEVASA---TNQKS----IIKTWARWSTITPLMVGLNVGVHDGRRHVPIYITE-NMVGH RLGEFTTTRNFRGHA------K--AEK--VSQVK-------- >CHLOFL_Dehalococcoides_sp_BAV1 Concatenation of 2 sequences MAIKIYRPTSPGRRHHSVSSFEE-ITKS------------RP-ERALLVSVKNDSGRNNQGRVTVRH-RGGGSKTQ---- IRVIDFK-R--NK-LDVPGRVAAIEYDPNRTARIALVFYT-DGEKRYILAPSDLKVGDVIMAGE-N-AE-PKSGNALPLS SIPTGTFIHNIEIIKGKGGIMVRSAGAAAQLMAK--EDDYALVRLPSGEMRKVRSDCSATVGQIGNIEHGTLEIGKAGRN -RHL-----GWR-P-TVRGSAMSPNNHPHGGGECRC-P--IGMTGPKTP---WGKPALGYRTR-KAKY-SD-K-LIVKRR --------------------------------MIQ---G-IIGKKIGMTQIFQ-EDGK---------AQPVTLVEAGPCV VVQVK----TEK----Q--DGY--EAVQLGY-------GK---ITS----------AVKGQC------------------ ---RG-FGEFKVLREVDV--------DDIAAV-----SV---GD-QITV----SDFKDGEKIDASGVSRGRGFSGVVKRW HFAG-GPKTHGQSDRHRA-PGSIGST-TTPG-RIYKGKHMAGHMGNEAVTIRNLVVLKTDAEKN---------------- ----------LLMVKGA-IPGGKNTIILIK--MEIPVYN-ASGEIV-KNINISEDVF----GV-PF-NEALVHQAFVAQQ ANARQGTQSTKTRGE--------VQ-GSSRKIY---------RQKGTGNAR--------MGT---NR-SP----VR---- RHGGVAFGPR-P-RDFSKDLPKKMRRQAIRCVLSFKLESG----------------E-LKVIDQL----SFD-E------ --PKTRLIA--VDNPD--T---NFIKSARNIPAVK-T---------------TPANLLNISDMLKNKQ----LVMTEEAV RQVELKVEERYTNAV-----PELQKFFNYGNIMQVPKLVKVVINTGVG-EAVSNSKAMETAEADIVAIAGQHPVVTRAKR SVANFKLRAGMPIGLKVTLRGQRMYDFLNKLFFITLPRVRDFQGVPN-TAFDERGNYTLGFKDHSVFPEID-----FNKI EKPRGLEICIVTT-----------------------ANTPEEGKKLLELLGMPFMSRIG-K--MPIKVPLGIKVD-I--- -N-G--N-DVTVKGPKGTLSRSF--RP-E--VTINREG-DY--LVV----A-P-VGTDKATR-AFFGLSRTLLDNMIVGV KDGFDKNLEIVGVGM--RADKDG-DK--VVFK--VGFSHSVTVAP-P-A-GITLSVD--G-TTKVKVSG-INKEDVGQMA AEIRSIR------KPDHY---MGKGIRYAGEYVRIKPGK----------MVQQYTRLNVADNTGAKKIMCINVLG-SHKI Q--AKVGDVIVAAVKKSSPD-A-------QAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILN-DKME-PKGTRIF GPVARELR-DKKFTKILSLAPEVLMR-L--HELSPAPGS-RKDRKRVG-RGDA-GR-GNYSGRGMKGQKARSGGA-T--- -RPGF-E-GGQLPIYLRLPRKRG--FFNVNIEQLVTPETLLAA-GLIRVK---------ILS--SGH-I-D-R-A-LEV- SAHKFSQAAKAQIEAAGGKV-K---VQR--GRR---DGAA-HKGNTVAFG----------EFALQSL--EAGWITARQIE ATRRAITRYI------RRGGQVWIRIFPDKPITKKPAETRQGGGK---------GAPEEWVAVVRR-GRIMFEI--GG-- VTPEAAKEAMRLASYKMPVKTRF-VAREARIVRHERLRKKV---SGTEARPRLCVFRSIENIYTQVIND---N--CGSTL VQASTK-DAEL-KAEL----DGK-TKTEQAVVIGNLIAKR--SLEAG-ISEVVFDRGGYKYH--GRVKALAEAARSGGLK F--------------------------------------------------------------ME-VKAIVKDTGYSALK VRLCVDLVRGKKVSEAITLLRFM---------------------------------TSPTAKVVSKVIKSAAAN----A- ENNF-QMNPADLKISQIYADEARMLKRMRPQARGRVSPILKRSSHITVVVAD-MRLKKNDNVLVIAGK------DK-GKT GKVRYAYPRTD--RVL--VEGVNMIKRHSR----AK--GQ-AKQ-AGIIEREAPLHVSNLM-LLCSKC-------NK--P --ARIGSRE---LA--------DGSVR---YCKSCN---EVI--MGRKVHPIGFRLG--II-KDWSAKWHA------SDK N--FAECLTEDLKLRKAI--SKKYV-----DAAISQVDIERQS-N-KVTVSVRTARPGIVIGRGGQRVDEMRHFLEDLVQ LNIVEISQ---AELDAFLVARSVAEQIERRVAYRRAMKQAIFRSMQA-GAKGIKICASGRLGGVEIARREVMHEGRVPL- -HTLRADIDYGCTRAHTALGDVGIKVWVY-MISDPIADMLTRIRNGVMARHEVVIM-PASRMKQYLAKVMKQEGFIAGYE VIG----A---K----PKRQLKIVLRYD---EGG-------A---SFVSGLERISKPGLRVYVQRGEIPRVYGGLGVAIV STSKGVMTGSQAWRQGLGGELLCKVWMAKQKIRIKLKGFDHKILDQSALQIVEALERTGATISGPVPLPTRIQRYSVIRA SFIDKDSQ-EQFEIRTHKRLIDIVETTSKTIDALTNLNLPAGVSIDIKLNKTRIGHVISDKMEKTIVVGIDVVKRHPLYK KTYRRTMKYLVHDEK--NEAKIGDMIEIVECRPISKGKYWRLSKIITKG------------------------------- -MSRSV-KKGPALCP-KLMKKVEVASA---TNQKS----IIKTWARWSTITPLMVGLNVGVHDGRRHVPIYITE-NMVGH KLGEFTTTRNFRGHA------K--AEK--VSQVK-------- >CHLOFL_Dehalococcoides_sp_CBDB1 Concatenation of 2 sequences MAIKIYRPTSPGRRHHSVSSFEE-ITKS------------RP-ERALLVSVKNDSGRNNQGRVTVRH-RGGGSKTQ---- IRVIDFK-R--NK-LDVPGRVAAIEYDPNRTARIALVFYT-DGEKRYILAPSDLKVGDVIMAGE-N-AE-PKSGNALPLS SIPTGTFIHNIEIIKGKGGIMVRSAGAAAQLMAK--EDDYALVRLPSGEMRKVRSDCSATVGQIGNIEHGTLEIGKAGRN -RHL-----GWR-P-TVRGSAMSPNNHPHGGGECRC-P--IGMTGPKTP---WGKPALGYRTR-K-AKYSD-K-LIVKRR --------------------------------MIQ---G-IIGKKIGMTQIFQ-EDGK---------AQPVTLVEAGPCV VVQVK----TEK----Q--DGY--EAVQLGY-------GK---ITS----------AVKGQC------------------ ---RG-FGEFKVLREVDV--------DDIAAV-----SV---GD-QITV-SD---FKDGEKIDASGVSRGRGFSGVVKRW HFAG-GPKTHGQSDRHRA-PGSIGST-TTPG-RIYKGKHMAGHMGNEAVTIRNLVVLKTDAEKN---------------- ----------LLMVKGA-IPGGKNTIILIK--MEIPVYN-ASGEIV-KNINISEDVF----GV-PF-NEALVHQAFVAQQ ANARQGTQSTKTRGE--------VQ-GSSRKIY---------RQKGTGNAR--------MGT---NR-SP----VR---- RHGGVAFGPR-P-RDFSKDLPKKMRRQAIRCVLSFKLESG----------------E-LKVIDQL----SFD-E------ --PKTRLIA--VDNPD--T---NFIKSARNIPAVK-T---------------TPANLLNISDMLKNKQ----LVMTEEAV RQVELKVEERYTNAV-----PELQKFFNYGNIMQVPKLVKVVINTGVG-EAVSNSKAMETAEADIVAIAGQHPVVTRAKR SVANFKLRAGMPIGLKVTLRGQRMYDFLNKLFFITLPRVRDFQGVPN-TAFDERGNYTLGFKDHSVFPEID-----FNKI EKPRGLEICIVTT-----------------------ANTPEEGKKLLELLGMPFMSRIG-K--MPIKVPPGIKVD-I--- -N-G--N-DVTVKGPKGTLSRSF--RP-E--VTINREG-DY--LVV----A-P-VGTDKATR-SFFGLSRTLLDNMIVGV KDGFDKNLEIVGVGM--RADKDG-DK--VVFK--VGFSHSVTVAP-P-A-GITLSVD--G-TTKVKVSG-INKEDVGQMA AEIRSIR------KPDHY---MGKGIRYAGEYVRIKPGK----------MVQQYTRLNVADNTGAKKIMCINVLG-SHKI Q--AKVGDVIVAAVKKSSPD-A-------QAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILN-DKME-PKGTRIF GPVARELR-DKKFTKILSLAPEVLMR-L--HELSPAPGS-RKDRKRVG-RGDA-GR-GNYSGRGMKGQKARSGGA-T--- -RPGF-E-GGQLPIYLRLPRKRG--FFNVNIEQLVTPETLLAA-GLIRVK---------ILS--SGH-I-D-R-A-LEV- SAHKFSQAAKAQIEAAGGKV-K---VQR--GRR---DGAA-HKGNTVAFG----------EFALQSL--EAGWITARQIE ATRRAITRYI------RRGGQVWIRIFPDKPITKKPAETRQGGGK---------GAPEEWVAVVRR-GRIMFEI--GG-- VTPEAAKEAMRLASYKMPVKTRF-VAREARIVRHERLRKKV---SGTEARPRLCVFRSIENIYTQVIND---N--CGSTL VQASTK-DAEL-KAEL----DGK-TKTEQAVVIGNLIAKR--SLEAG-ISEVVFDRGGYKYH--GRVKALAEAARSGGLK F--------------------------------------------------------------ME-VKAIVKDTGYSALK VRLCVDLVRGKKVSEAITLLRFM---------------------------------TSPTAKVVSKVIKSAAAN----A- ENNF-QMNPADLKISQIYADEARMLKRMRPQARGRVSPILKRSSHITVVVAD-MRLKKNDNVLVIAGK------DK-GKT GKVRYAYPRTD--RVL--VEGVNMIKRHSR----AK--GQ-AKQ-AGIIEREAPLHVSNLM-LLCSKC-------NK--P --ARIGSRE---LA--------DGSVR---YCKSCN---EVI--MGRKVHPIGFRLG--II-KDWSAKWHA------SDK N--FAECLTEDLKLRKAI--SKKYV-----DAAISQVDIERQS-N-KVTVSVRTARPGIVIGRGGQRVDEMRHFLEDLVQ LNIVEISQ---AELDAFLVARSVAEQIERRVAYRRAMKQAIFRSMQA-GAKGIKICASGRLGGVEIARREVMHEGRVPL- -HTLRADIDYGCTRAHTALGDVGIKVWVY-MISDPIADMLTRIRNGVMARHEVVIM-PASRMKQYLAKVMKQEGFIAGYE VIG----A---K----PKRQLKIVLRYD---EGG-------A---SFVSGLERISKPGLRVYVQRGEIPRVYGGLGVAIV STSKGVMTGSQAWRQGLGGELLCKVWMAKQKIRIKLKGFDHKILDQSALQIVEALERTGATISGPVPLPTRIQRYSVIRA SFIDKDSQ-EQFEIRTHKRLIDIVETTSKTIDALTNLNLPAGVSIDIKLNKTRIGHVISDKMEKTIVVGIDVVKRHPLYK KTYRRTMKYLVHDEK--NEAKIGDMIEIVECRPISKGKYWRLSKIITKG------------------------------- -MSRSV-KKGPALCP-KLMKKVEVASA---TNQKS----IIKTWARWSTITPLMVGLNVGVHDGRRHVPIYITE-NMVGH KLGEFTTTRNFRGHA------K--AEK----VSQ------VK >CHLOFL_Dehalococcoides_sp_GT Concatenation of 2 sequences MAIKIYRPTSPGRRHHSVSSFEE-ITKS------------RP-ERALLVSVKNDSGRNNQGRVTVRH-RGGGSKTQ---- IRVIDFK-R--NK-LDVPGRVVAIEYDPNRTARIALVFYT-DGEKRYILAPSDLKVGDVIMAGE-N-AE-PKSGNALPLS SIPTGTFIHNIEIIKGKGGIMVRSAGAAAQLMAK--EDDYALVRLPSGEMRKVRSDCSATVGQIGNIEHGTLEIGKAGRN -RHL-----GWR-P-TVRGSAMSPNNHPHGGGECRC-P--IGMTGPKTP---WGKPALGYRTR-K-AKYSD-K-LIVKRR --------------------------------MIQ---G-IIGKKIGMTQIFQ-EDGK---------AQPVTLVEAGPCV VVQVK----TEK----Q--DGY--EAVQLGY-------GK---ITS----------AVKGQC------------------ ---RG-FGEFKVLREVDV--------DDIAAV-----SV---GD-QITV-SD---FKDGEKIDASGVSRGRGFSGVVKRW HFAG-GPKTHGQSDRHRA-PGSIGST-TTPG-RIYKGKHMAGHMGNEAVTIRNLVVLKTDAEKN---------------- ----------LLMVKGA-IPGGKNTIILIK--MEIPVYN-ASGEIV-KNINISEDVF----GV-PF-NEALVHQAFVAQQ ANARQGTQSTKTRGE--------VQ-GSSRKIY---------RQKGTGNAR--------MGT---NR-SP----VR---- RHGGVAFGPR-P-RDFSKDLPKKMRRQAIRCVLSFKLESG----------------E-LKVIDQL----SFD-E------ --PKTRLIA--VDNPD--T---NFIKSARNIPAVK-T---------------TPANLLNISDMLKNKQ----LVMTEEAV RQVELKVEERYTNAV-----PELQKFFNYGNIMQVPKLVKVVINTGVG-EAVSNSKAMETAEADIVAIAGQHPVVTRAKR SVANFKLRAGMPIGLKVTLRGQRMYDFLNKLFFITLPRVRDFQGVPN-TAFDERGNYTLGFKDHSVFPEID-----FNKI EKPRGLEICIVTT-----------------------ANTPEEGKKLLELLGMPFMSRIG-K--MPIKVPPGIKVD-I--- -N-G--N-DVTVKGPKGTLSRSF--RP-E--VTINREG-DY--LVV----A-P-VGTDKATR-SFFGLSRTLLDNMIVGV KDGFDKNLEIVGVGM--RADKDG-DK--VVFK--VGFSHSVTVAP-P-A-GITLSVD--G-TTKVKVSG-INKEDVGQMA AEIRSIR------KPDHY---MGKGIRYAGEYVRIKPGK----------MVQQYTRLNVADNTGAKKIMCINVLG-SHKI Q--AKVGDVIVAAVKKSSPD-A-------QAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILN-DKME-PKGTRIF GPVARELR-DKKFTKILSLAPEVLMR-L--HELSPAPGS-RKDRKRVG-RGDA-GR-GNYSGRGMKGQKARSGGA-T--- -RPGF-E-GGQLPIYLRLPRKRG--FFNVNIEQLVTPETLLAA-GLIRVK---------ILS--SGH-I-D-R-A-LEV- SAHKFSQAAKAQIEAAGGKV-K---VQR--GRR---DGAA-HKGNTVAFG----------EFALQSL--EAGWITARQIE ATRRAITRYI------RRGGQVWIRIFPDKPITKKPAETRQGGGK---------GAPEEWVAVVRR-GRIMFEI--GG-- VTPEAAKEAMRLASYKMPVKTRF-VAREARIVRHERLRKKV---SGTEARPRLCVFRSIENIYTQVIND---N--CGSTL VQASTK-DAEL-KAEL----DGK-TKTEQAVVIGNLIAKR--SLEAG-ISEVVFDRGGYKYH--GRVKALAEAARSGGLK F--------------------------------------------------------------ME-VKAIVKDTGYSALK VRLCVDLVRGKKVSEAITLLRFM---------------------------------TSPTAKVVSKVIKSAAAN----A- ENNF-QMNPADLKISQIYADEARMLKRMRPQARGRVSPILKRSSHITVVVAD-MRLKKNDNVLVIAGK------DK-GKT GKVRYAYPRTD--RVL--VEGVNMIKRHSR----AK--GQ-AKQ-AGIIEREAPLHVSNLM-LLCSKC-------NK--P --ARIGSRE---LA--------DGSVR---YCKSCN---EVI--MGRKVHPIGFRLG--II-KDWSAKWHA------SDK N--FAECLTEDLKLRKAI--SKKYV-----DAAISQVDIERQS-N-KVTVSVRTARPGIVIGRGGQRVDEMRHFLEDLVQ LNIVEISQ---AELDAFLVARSVAEQIERRVAYRRAMKQAIFRSMQA-GAKGIKICASGRLGGVEIARREVMHEGRVPL- -HTLRADIDYGCTRAHTALGDVGIKVWVY-MISDPIADMLTRIRNGVMARHEVVIM-PASRMKQYLAKVMKQEGFIAGYE VIG----A---K----PKRQLKIVLRYD---EGG-------A---SFVSGLERISKPGLRVYVQRGEIPRVYGGLGVAIV STSKGVMTGSQAWRQGLGGELLCKVWMTKQKIRIKLKGFDHKILDQSALQIVEALERTGATISGPVPLPTRIQRYSVIRA SFIDKDSQ-EQFEIRTHKRLIDIVETTSKTIDALTNLNLPAGVSIDIKLNKTRIGHVISDKMEKTIVVGIDVVKRHPLYK KTYRRTMKYLVHDEK--NEAKIGDMIEIVECRPISKGKYWRLSKIITKG------------------------------- -MSRSV-KKGPALCP-KLMKKVEVASA---TNQKS----IIKTWARWSTITPLMVGLNVGVHDGRRHVPIYITE-NMVGH KLGEFTTTRNFRGHA------K--AEK----VSQ------VK >CHLOFL_Dehalococcoides_sp_VS Concatenation of 2 sequences MAIKIYRPTSPGRRHHSVASFEE-ITKS------------RP-ERALLVSVKNDSGRNNQGRVTVRH-RGGGSKTQ---- IRVIDFK-R--NK-LDVPGRVAAIEYDPNRTARIALVFYT-DGEKRYILAPSDLKVGDVIMAGE-N-AE-PKSGNALPLS AIPTGTFIHNIELIKGRGGIMVRSAGAAAQLMAK--EGDYALVRLPSGEMRKVRSDCSATVGQIGNIEHGTLEIGKAGRN -RHM-----GWR-P-TVRGSAMSPNNHPHGGGECRC-P--IGMTGPKTP---WGKPALGYRTR-K-AKYSD-K-LIVKRR --------------------------------MIQ---G-IIGKKIGMTQIFQ-EDGK---------AQPVTLVEAGPCV VVQVK----TEK----Q--DGY--EAVQLGY-------GK---ITS----------AVKGQC------------------ ---RG-FGEFKVLREVDV--------DDIATV-----NV---GD-QITV-SD---FKDGEKIDASGVSRGRGFAGVVKRW HFAG-GPKTHGQSDRHRA-PGSISST-TTPG-RIYKGKRMAGHMGNDAVTIRNLVVLKTDAEKN---------------- ----------LLMVKGA-IPGGKNTIILIK--MEIPVYN-ASGEII-KNISISEDVF----GV-PF-NEALVHQAFVAQQ ANARQGTQSTKTRGE--------VQ-GSSRKIY---------RQKGTGNAR--------MGT---NR-SP----VR---- RHGGVAFGPR-P-RDFSKDLPKKMRRQAIRCVLSFKLESG----------------E-LKVIDQL----SFE-E------ --PKTRLIA--VDNPD--T---NFIKSARNIPSVK-T---------------TPANLLNISDMLKNKQ----LVMTEEAV RQVELKVEERYTNAV-----PELQKIFKYENIMQVPKLVKVVINTGVG-EAVSNSKALETAEADIVAIAGQHPVITRAKR SVANFKLRAGMPIGLKVTLRGQRMYDFLNKLFFITLPRVRDFQGVSN-TAFDEHGNYTLGFKDHSVFPEID-----FNKI EKPRGLEVCIVTT-----------------------ANTPEEGKKLLELLGMPFMSRIG-K--MPIKVPPGVTVD-I--- -K-G--N-DVTVKGPKGTLSRTF--RP-E--VTITREG-DH--LVV----A-P-VGTDKTAR-SFFGLSRTLLDNMIVGV KDGFDKNLEITGVGM--RVDKDG-NN--IVLK--VGYSHTVTVAP-P-A-GITLSVD--G-TTKVKVSG-INKEEVGQMA AEIRSVR------KPDHY---MGKGIRYAGEYVRIKPGK----------MVQQYTRLNVADNTGAKKIMCINVLG-SRKI Q--AKVGDVIVAAVKKSSPD-A-------QAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILN-DKME-PKGTRIF GPVARELR-DKKFTKILSLAPEVLMR-L--NELSPAPGS-RKDRKRVG-RGDA-GR-GNYSGRGMKGQKARSGGA-T--- -RPGF-E-GGQLPIYLRLPRKRG--FFNVNIEQLVTPETMLAA-GLIRVK---------ILS--AGH-I-D-R-A-LEV- SAHKFSQAAKAQIEAAGGKV-------------------------------------------MQSL--EAGWITARQIE ATRRAITRYI------RRGGQVWIRIFPDKPITKKPAETRQGGGK---------GAPEEWVAVVRR-GRIMFEI--GG-- VTPEAAKEAMRLASYKMPVKTRF-VAREARIVRHERLRKKV---SGTESRPRLCVFRSIENIYTQVIND---N--CGSTL VQASTK-DAEL-KAEL----DGK-TKTEQAVVIGNLIAKR--SLEAG-ISEVVFDRGGYKYH--GRVKALAEAARSGGLK F--------------------------------------------------------------ME-VKAIVKDTGYSALK VRLCVDMVRGKKVSEAITMLRFM---------------------------------TSPTAKVVSKVIKSAAAN----A- ENNF-QMNPADLKISQIYADEARMLKRMRPQARGRVSPILKRSSHITVVVAD-MRLKKNDNVLVIAGK------DK-GKT GKVRYAYPRTD--RVL--VEGVNMIKRHSR----AK--GQ-AKQ-AGIIEREAPLHVSNLM-LLCSKC-------NK--P --ARIGSRE---LA--------DGSVR---YCKSCN---EVI--MGRKVHPIGFRLG--II-KDWSAKWHA----S-D-K G--FAECLTEDLKLRKAI--AKKYV-----DAAISQVDIERQS-N-KVTVSVRTARPGIVIGRGGQRVDEMRHFLEELVQ LNIVEISQ---AELDAFLVARSVAEQIERRVAYRRAMKQAIFRSMQA-GAKGIKVCASGRLGGVEIARREVMHEGRVPL- -HTLRADIDYGCTRAHTALGDIGIKVWVY-MISDPIADMLTRIRNGVMARHEVVIM-PASRMKQYLAKVMKQEGFIAGYE VIG----A---K----PKRQLKIVLRYD---EGG-------A---SFVSGLERISKPGLRVYVQRGEIPRVYGGLGIAIV STSKGVMTGSQAWRQGLGGELLCKVWMTKQKIRIKLKGFDHKILDQSALQIVEALERTGATISGPVPLPTRIQRYSVIRS SFIDKDSQ-EQFEIRTHKRLIDIVETTSKTIDALTNLNLPAGVSIDIKLNKTRIGHVISDKMEKTIVVGIDVAKRHPLYK KTYRRTMKYLVHDEK--NEAKIGDMIEIVECRPISKGKYWRLSKIITKG------------------------------- -MSRSV-KKGPALCP-KLMKKVEVASA---TNQKS----IIKTWARWSTITPLMVGLNVGVHDGRRHVPIYITE-NMVGH KLGEFTTTRNFRGHA------K--AEK----VSQ------VK >CHLOFL_Dehalogenimonas_lykanthroporepellens_BL-DC-9 Concatenation of 2 sequences MGLKQYKPTSAGRRHQSGFDFSE-VTKS------------RP-EKSLVKRVKNNAGRNSQGRMTVRH-RGGGAKKM---- IRVIDFK-R--DK-IGVPGRVAAIEYDPHRSARIALIFYA-DGEKRYILAPQGLKVDDRVMASP-E-AE-LRVGNALPLN SMPSGTVIHNIEMEPGRGGKLVRSAGAGAQLMAK--EGDYALLRLPSGEMRRVRVSAYATVGQVGNEDHQTLSIGKAGRK -RHM-----GWR-P-QVRGSAMNPADHPHGGGEGRS-P--IGMPGPKTP---WGKPALGYKTR-QKSKASN-K-LIVKRR --------------------------------MIN---G-IIGKKLGMTQVYS-TEGK---------MEPVTVLQVGPCT VVQVK----TPE----R--DGY--TAAQLGF-------GE---LTK----------AEQGHVE----------------- ------YGNFRHLREFRL--------DDLDGV-----EV---GA-RVDA--S-L-FVDGERVDVTGISKGRGFAGTVKRH GFAG-GPKTHGQSDRHRA-PGSIGAT-TTPG-RVFKGTRMAGHMGNEQVTVSGLKVVKTDVEKN---------------- ----------LLLVKGA-VPGARNGLILIK--MEIPVYN-TSGQVV-RNVTVSDELF----AV-PM-NDAVVHQAMVAQA ANARQGTSSTRTRSE--------VS-GTTQKMF---------RQKGTGEAR--------AGS---RK-SG----LR---- PGGGVIFGPK-P-RDYSKSLPKKMRRLAIRCLLSDKVASG----------------S-LKVVDAL----ALD-A------ --PKTRIIA--TAGVD--E---NVVLSARNLPRVK-T---------------TPANLINVGDLLKYDT----LLLTEQAL EVVQAGLREKYLNET----VTRLTEAYGYRNIMEVPRLTKVVINVGVGKEASSNPKVVETVQEDLAAIAGQHPVITRSKR SIANFKLREGMPVGLKVTLRGNNMYNFLDKLISVVLPRLRDFQGVPQ-DAFDGRGNYALGLKEHSVFPEID-----FSKI DKIRGLEVCIVTT-----------------------AKTDAESRTLLEGIGMPFMSRIG-K--LPVALPQGVKVTIA--- -DSG-----VTVSGPKGELKRSF--DP-V--MIIKEED-GK--LVV---ER-P--SDAPAHR-AMHGLTRSLLANMVKGV SDGYEKGLDIVGVGF--KAEKAG-EK--LILR--VGYSHVVEIPA-V-D-GVTFTVE--T-PTKLKVSG-IDKQKVGQVA AEIRSVR------KPDSY---KGKGIRYAGEVIKLKPGK----------MIQSYTRLKAADNTGIKSLMCINVLG-SRKL R--ARIGDVIVCSVKRAAPD-A-------AIKEGSVVKAVVVRQVAPLRRSDGSYIKFDENAAVVIN-DKNE-PRGTRIF GPVARELR-DKKFLKIVSLAPEVLMK-E--HELFPSPGA-RKERKRIG-RGDASGH-GTYSGKGLKGQKARAGGG-V--- -RPGF-E-GGQNPLIKKLPQKRG--FVNVNVGDLITPELLAAR-NLIRVK---------ILA--DGE-I-D-R-A-LVV- KANAFTVAARSKIETAGGKA-K---SHK--GHR---HGEA-QAGNKLDFG----------DYGMQAT--STAWVTSRQIE AARRAMTRYI------KRGGKIWIRIFPDHPVTKKPAETRMGSGK---------GSPDHWIAVVKR-GRMMFEM--TG-- VAEEVAREAMRLASHKLPLQTKF-VSRYARKLRHIRLRKKL---EGTTACPRLCVFRSLEHIYAQVIDD---S--RGMTL VQASTL-DAEL-KEQ-----ANG-TKISQAELVGTAIARR--AQDAG-IKEVVFDRGGFKYH--GRVKALAEAARAAGLS F--------------------------------------------------------------MQ-VKAMSKNTGVSPRK VRLYVDLVRGKGVDEALSILRYM---------------------------------PSPTAGLVAKTVKSAAAS----A- ENNY-QMEPNELKIIKIYADGAPMMKRHRPRSRGRVSPILKRSSHITVIVAD-MKIKKDDNVLVIAGK------DR-GKS GKVRQVTSEDR---VM--VEGVNMVKKHAR----PR--AQ-ARQ-AGIIEREAPIHASNLM-LLCSKC-------SK--P --ARLGKRT---LA--------DGKVR---FCKSCG---EVI--MGRKVHPYAFRIG--AI-KGWNSKWFA------E-K D--FSTNLLEDLKIRKAI--KKKYA-----DAGISNIEIERQA-A-KITVTVSTSRPGIVIGRGGQRVDEMRRYLEEVIQ LNIHEIGQ---AELDAYLVARSVADQMERRIAYRRAMKQAMFRTRQA-GAQGIKIKCAGRLGGVEIARQEEMHNGRVPL- -HTIRADIDYGFAEAHTPLGRIGVKVWVY--MTDPIADMLTRIRNATMAGHEVTLI-PESRIKQNIARLLKQEGFISGFE VVG----D---K----PKRQIKIALRYD---EKG-------V---PMVNGLERISKPGLRIYVQRGEIPRVYGGLGVAVV STSRGVMTGYQAWRQGVGGELLLKVWMGKQKIRIKLKGFDHKILDQSAVQIVEALERTGAVISGPVPLPTKIKKYSVIRS AFIDKDSQ-EQFEIRTHRRLIDIVETTSKTIDSLTSLNMPAGVDIDIKLVKKSVGRVVSDKMNKTIVVAIETRRQHPIYK KSYKVVKKYKVHDEK--GEAAYGDTVEIIPTRPLSSTKHWRLGQILSRG------------------------------- -MSRSV-KKGPAVSP-KLMKKVDQANR---AGKKV----MIKTWARWSTILPEMVGLNFGVHDGRRHVTVFVTE-NMVGH KLGEFAPTRTYRGHL------G---------KSE-VKTKGKK >CHLOFL_Herpetosiphon_aurantiacus_ATCC_23779 Concatenation of 2 sequences MGIKRYKPTSPGRRGMTVSDFAE-ITKF------------EP-EKSLTEPLKKHAGRNNHGHITTRH-RGGGHKRR---- YRLIDFK-R--KK-FDIPAKVAGIEYDPNRSANIALLHYT-DGEKRYIIAPLGLKVGDTLMAGP-N-AE-IRVGNALPLA NIPIGSQIHNIELTPGRGGQLVRSAGNTAQLMAR--EGNYATVRLPSGEMRMVHIKCMATLGQVGNVDHQNIMIGKAGRS -RWL-----GRR-P-VVRGSAMNPVDHPHGGGEGRA-P--TGM-NPKTK---WGKPAMGKKTR-HNPR-TQ-R-FIVRTR --------------------------------MLN---G-ILGRKIGMTQIFT-EKGE---------TIPVTVIEAGPCV VTQLR----TKD----K--DGY--EAVQLGF-------GE--IVTK----------PIQGHLK----------------- ---AA-GRLVRFMREVKT--------TDLNAH-----NV---GD-VVNV--D-I-FQIGEKIDVVGTSKGRGFAGVVKRH GFRG-GPATHGQSDRHRA-PGSIGSG-TTPG-RVWKNMRMAGRMGNDRVTVQNLEVVKIDLERH---------------- ----------VILVKGS-VPGAKNGLVMVS--MEAKLYN-QAGQAI-GTLELQDYIF----GI-EP-NIPVMHQAVIRQL ANARLGTHSTKTRGE--------VR-GSTRKLY---------RQKGTGRAR--------QGA---IR-AP----HH---- SGGGVVHGPK-P-RKYTKAMPRKMRRLAVRSALSAKYAEN----------------Q-IIFLDDL----SLN-A------ --PKTKLVA--LGEK-----SDNITLSASNLPNVK-T---------------LLAAYLNVRDLLTYDT----LILPKSAL SVVEARLKDVYLKTV----APALFKDFGFKSPMQVPRITKIVINIGLG-EALQNPKAVEAAIGDLTMIAGQKPVVTRAKK SLAAFKLRQGMPIGAMVTLRNDRMYDFYDRLVNLALPRIRDFQGLSR-KSFDGRGNYSIGIREQIIFPEIE-----YDKV DKIRGLEVAIVTT-----------------------APNDEQGFALLKALGMPFMSRIG-R--KPIEVPAGVTVN-V--- -D-S-NN-LVTVKGPKGTLSESI--RP-E--VTVNING-AT--VEI---TR-V--NDSRQAR-AFHGLSRTLVANMVDGV TKGFEKTLEMNGTGY--RATLDG-KT--LVLS--LGFSHPVRVEP-Y-E-GNSFEV---A-ERRVVIKG-PNKQKVGDQA ANIRKLR------PPEPY---LGKGIKYSDEVIRRKAGK----------MIQQESRMRVADNTGAKELLCIRVLG-TKRR Y--ASVGDTIIATVKQANPG-G-------SAKKGEVVRAVIVRVKKGYTRPDGSMIQFDDNAAVIIN-QQGN-PRGTRIF GPVARELR-EKQYMKIISLAPEVLMK-L--HDLKPAPGS-TRKSKRVG-RGHGSGK-GKTSGKGMMGQKARSGPN-P--- -YPHF-E-GGQNPLVRRMPYKRG--FTNVNVGDLVTPEALREV-GLIKIK---------VLG--DGD-L-N-V-A-LKV- RVHKVSASARQKIEAAGGSV-R---PHR--PRN--IKGIA-QRGATVAFG----------DFGLVSL--EAGWITSRQIE SARRTITNYV------KRGGKVWIRIFPDRPITQKPAETRMGSGK---------GSVEYYVAVIKP-GRVLFEL--NG-- VPEDVAQEALRRAAQKLPVKCKF-VSRELRARRHRRLRGQL---SGTPERPRLNVFRSGLNIYAQVIDD---L--AGHTL VSASTI-DTEL-RGSL----GEQ-RKLEQAHSVGKAVAER--ARAAG-ITKVVFDRGGYKYH--GRVKAVAEGAREGGLE F--------------------------------------------------------------MQ-AKAILRNFRMSPQK VRLVADLVRGKNVTEALGILQYL---------------------------------PHKAAPEIARVIKSAKAN----A- DHNY-QMSPEDLVVKTIMVDAGPVLKRYMPRARGRGDRILKRSSHITVIVDD----------MVLSGR------EK-GRE GVIKLSLPKKE--RVV--VENVNIVKKHVK----PM----GNRQ-GGILEVEAALHVSKVM-LICPAC-------GK--P --SRTGHRV---ND--------EGKVR---VCKQCN---ADV--M----HPNGFRLG--II-KDWKSKWFA------E-R N--YTEQLHQDLALRKYIEGADELK-----NAGVALVDIERSA-N-RVEVTIHTAKPGIVIGKRGANVDTLKNQIEKLVR LNIQEIHQ---PELNAYLVAESVAEQISKRVSHKRAMKQATQRAMRL-GAQGIKVKCSGRLGGAEMSRSLWEREGRVPL- -HTIRADIDYALVHAHTTYGRIGVKVWIYMSVNDPIADLLTRIRNAGMARHQTVTI-PLSKIKRGIAEILQAEGYIKSFE VQE----G---T----PFSNLVLTLKYA---ADR-------K---PVITGLKRVSRPGLRVYTKRNEIPRVRNGLGLSIL STPKGLMTGDAAWKAGVGGEIVCYIW-------------------------MDAAERTGAQVAGPVPLPTKIEKYSVLRS PFIDRDSQ-EQFEIRTHKRLIDVIDPSQQTINALMKLNLPAGVDIEIKLRKQKVGRVVSNKMNKTVVVAVDYLRPHPLYR KTVRQTSKFYAHDEN--NECHVGDTVVIEETRPLSKLKRWRVVEIATKN------------------------------- ------------------MSRVETMNR---GNEKR----PLKTWSRDSTIFPQMVGHTIAVHDGRRHVPVYITE-NMVGH KLGEFAPTRTFRGHG------GKKADK----RGK------LK >CHLOFL_Ktedonobacter_racemifer_DSM_44963 Concatenation of 2 sequences MPIRQYRPTSPGRRGMSVSTFEE-ITKT------------KP-EKSLTVSLKKHSGRNNQGKITTRH-RGGGAKRA---- YRIIDFK-R--NK-FGVPARVAAIEYDPNRSANIALLHYL-DGEKRYIIAPLGLKVGDRVEAGP-E-AD-IRVGNALPLK NIPTGTTVHNVEMERGRGGQLARGAGVGIQLMAK--EGDYALLRLPSGELRNVHILCMATIGQVGNLDHENVSIGKAGRS -RHM-----GRR-P-TVRGSVMNPRDHPHGGGEGRA-P--IGGK-PQTP---WGKPAMGFKTR-RNKRTNR---FIVRRR --------------------------------MLD---A-LLGRKVGMTQVFG-QNGT---------VIPVTVIEVGPCI VTQVK----TVA----R--DGY--EAVQIGF-------EE--TSTR----------PELGHLG----------------- ---PE-LGPFKVLREVGLQEGVD---L-G-SV-----EL---GH-SFNA--S-L-FTDGEIVDIVGITKGKGFQGGVKRH GFRG-GPRTHGQSDRLRA-PGSIGSG-TTPG-RVLKGTRMAGRMGNARVTVKKLQIVQSDPERN---------------- ----------LLVVKGS-VPGANGGLLTIK-MPSTTVYN-MAGEAV-EQLELSEQVF----GV-TP-NMAVLHQVVTAQL VNRRQGNASTKTRSE--------VS-GGNKKPY---------RQKGTGRAR--------QGS---TR-AP----QF---- RGGGTVFGPK-P-HPYHHDVPKKMRRLAIRSVLSDKVANQ----------------S-LIIVNKL----EME-T------ --PRTKLMM--LPKRD--E---NVVLSTRNIPSAK-V---------------QHVSSINVVELLKHDY----IVMTPKTV RWIESRLKEKYRQEV----VPALHKEFNYANPMQVPGIHKVVVNIGMG-EVIQNAKAMDAAVADLATITGQRPVVTRAKR SVAAFKLREGMPIGCMVTLRGTRMFHFLDKLINVALPRIRDFQGISA-DAFDGRGNYTLGLREQLVFPEID-----YDKV DKLRGMEVSIVTT-----------------------ARTDEEGRRLLALMGMPFMSRIG-R--APITVPQAVQVNWT--- -E-D--N-LVTVKGPKGTLSEQV--DP-Q--LQLKLED-GT--LTV---TR-P--SDSREHR-SKHGLYRTLINNMVVGV TTGYTKMLEIHGVGY--RAVQQG-KN--LIIL--VGYSHPVEVQA-P-Q-GIELKLEAPD-PARISVTG-IDKHAVGQLA ANIRQIR------KPEPY---KGKGIRYAGEAVRRKAGK----------MIQPQTRLKVADNTGAKEIMCIRVMG-SAKR Y--AEVGDIIKASVKVATPN-G-------QVKKGEVVNAVVVRVTKEYVRRDGSHIRFDENAAVILA-PGNN-PRGTRIF GPVARELR-EKNFMRLVSLAPEVLIN-L--SNLQPAPGS-HKTEKRLG-RGHGSGR-GKTAGRGTKGQKARTGGR-V--- -HRAF-N-GGQTRLSKRLPFLRGLGNQNINVIDLVTPEAMVEK-GLLIIK---------VLG--DGE-I-D-R-A-LTV- RAHKFSASAKEKIEAAGGRIMR---QHR--GRM---RGEA-TRGATLAFG----------DFGLQAL--EPCWMEARQIE SARIAMTRYM------KRGGKVWIRVFPDKPITAKPAETRMGSGK---------GAVDHWVAVVKP-GRIIFEI--GG-- VSEEIAKEAIRLAIHKLPVKCRF-IANQARLRRHQRIRRHL---EGSELRPRLNVFRSGRHIYAQIIDD---T--TGKTL VSASTL-DESL-RDFK--PVTTE-QHKQAAHEVGKLVAQR--AQEKG-VKQVVFDRGGYAYH--GRVAALAEGAREAGLD F--------------------------------------------------------------MQ-VRAIAKDIGISPRK MRLVTNAVKGLRVNEALAILQYL---------------------------------PNAGATPVRKVVASAAAN----A- ENNY-SLNPDDLYILNIVADDSFRIKRVKPRSHGRAARILRRFCHVTVIVSD-MNIKKGDTVLIITGK------DK-SKE GTVSRALPQDR--KVI--VEGLNVVKKHVK----PQ--GQ-TRQ-GGIIEKAMPLHVSNVM-LKCTEC-------NE--P --TRVGHER---RV--------MGSVR---ICKHCG---KVI--MGHKVHPIGFRLG--VI-KSWQSRWYA------E-N N--YKDVLAEDIQIRRMI--NKELSSAHGADAGVSKIEIERAAPK-QVLVKINTAKPGIVIGKSGEKVERLKAHLESKVR VEIVEIRQ---PELDAYLVGRSICDQLEKRVSFRRAMKQAVQKSMRA-GAKGIKVIAGGRLGGAEIARTEKEVEGKVPL- -HTLRADIDYGLAEAHTTFGVIGVKVWIYMNMTDPIADMLTRIRNAATARHTRVLI-PASKMKLAIARVLKEEGYIKDIE ILK----D---N----PQGTLRLTLRYV----EK-------K---PVLTQLKRVSKPGLRVYSKQTDIPRVRGGLGISIV STSRGLMTGASAYKQGVGGEVICYVWGSKQRIRIRLKAFDHRILDQSAMQIVDAAQRTGARVSGPVPLPTKIEKYTVMRS PFIDKDAR-DQFEIRTHKRLIDIVDHTNKTVEALTHLNLPAGVDIEIKLRVQKVGRVISNKMDKTIVVSVESLKKHRIYK RTYKQTKHFHVHDEN--NQCQIDDVVRIEETRPMSKLKRWRLVEIVKSG------------------------------- -MSRSR-KKGPYIHE-SLRKKVLVMRK---SGDRR----LIKTWSRASMIFPEMVGMTIGVHNGKTHVPIYITE-NMVGH KLGEFAPTRHYRGHA------GGKNEK----TTS------VR >CHLOFL_Oscillochloris_trichoides_DG6 Concatenation of 2 sequences MGVRKYKPTSAGRRNMSVSTFED-ITKK------------RP-ESRLIEPLRKQAGRNNTGRITVRH-RGGGHKRF---- YRIIDFK-R--NK-LGIPAKVQAIEYDPNRSARIALLAYV-DGEKRYIIAPVGLKVGDTLSSGP-D-AD-IRVGNALPLA SIPLGTQIHNVELEIGRGGVLVRSAGTSAQLMAK--EGDYATIRMPSGEMRMIHIRCMATIGQVGNVDHQNVRLGKAGRS -RWL-----GRR-P-RVRGTVMNPRDHPHGGGEGRA-P--RGMSTPKTK---WGKPARGVKTR-HNPR-SD-R-FIVRRR --------------------------------MIS---G-MLGRKLGMMQVFS-DKGE---------VIPVTVIAAGPCI VTQVR----TVE----R--DGY--AAVQIGY-------EQ--VLTK----------PQQGHLK----------------- ---AA-NAMLRYLREFPA--------DNPQEH-----TP---GE-VINV--E-L-FKPGQKIDVSGTSKGRGFAGVVKRH GFRG-GPKTHGQSDRHRA-PGSIGAG-TTPG-RVWKGQKMAGRMGGKRVTIQNLEVVEVLPEKN---------------- ----------LILVKGS-VPGARTGLLEIR--MEATLYN-QAGEQI-GSIALNESIF----GI-EP-NVPVMHQYVVMQR ANARLGTHNTRGRGE--------VS-GSTKKLY---------RQKGTGRAR--------QGS---IR-AP----HR---- MGGGIAHGPH-P-RSYRLNMPKKMRRLAVRSALSAKLAAN----------------Q-IRFVDAL----TLE-K------ --PRTKLIV--IDQKN--AQTGNVRLSANNLPDVQ-I---------------LLAHYLNVRDLLTCDT----VVLPKAAV AVIEVRLREKYLSEI----VPALMQEFKYSSVMQVPRLTKVVVNIGVG-EAVQNSKALDAAVADLTTITGQKPVITKAKK SIASFKLREGMAIGTMVTLRSERMYDFLDRLVNLALPRIRDFRGVSR-SSFDGRGNYSLGLREQIVFPDID-----YDKI DKIRGLEVVIVTT-----------------------ATDDEQAYALLKRLGMPFMSRIG-K--KPITLPKGITVE-I--- -AQG--N-LVTVKGKKGSLTQQL--HP-D--MIIEQDA-ET--LTV---TR-P--SDSKLHR-SLHGLTRTLLSNMVVGV TDGWERKLEINGVGY--RAQLEG-KT--LVLQ--LGFSHPVRIDP-P-A-NVEFVVN--E-PLGLLVKG-IDKQVVGEMA SRIRGLR------PPEPY---KGKGVKYAEEKIRRKAGK----------MIQPQSRLKIADNTGAKEIMCIRVLG-SRVR Y--GRVGDVIVASVKQAAPG-G-------SVKKGEVVRAVIVRTTKEYGRPDGSHIRFDDNAAVIIG-KENN-PRGTRIF GPVARELR-EKQFMRIVSLAPEVLMK-L--HDLKPAEGA-NKKSKRLG-RGAGSGK-GKTGGKGMMGQKSRSGSN-P--- -YRTF-E-GGQNRLVKRMPYKRG--FTNLNVGDLVTPESLLEA-RAVRVK---------ILG--DGE-I-S-V-A-LTV- KAHKFSTSARQKIEAAGGTV-K---QQR--GRN---RGLA-YRGSGVVFG----------EYGLMAL--ESTWITSRQIE AARRTITNYI------KRGGKVWIRIFPDKPVTQKPAETRMGGGK---------GSVDHWVAVIKP-GRVMFEL--GG-- VSEEIALEALRRAAQKMPIPCKI-I---------------------------MNIFRSNIHIYAQVIDD---T--LGHTL AAASTN-EKAW-PVSE----TKM-TKTEQAALVGKLVAER--ALEAG-VTKVVFDRGGFKYH--GRVKALAEAAREAGLN F-------------------------------------------------------------AME-VKAITRYVRISPLK VRLVMDVVRGMKVDRALSTLQYM---------------------------------PQKAAREVARTIKSAAAN----A- EHNF-DMDPDDLVITQIYADQGPVLKRFMPRARGMANHIRKPTTHITVIVDD-MHVKTGDEVLIIAGK------NK-GQR GKIKRVIPNMS--RVV--VEGKNIVKRHMK----AR--GP-GKP-GGIVEMEAPLHSSNVM-LICPSC-------GH--A --TRTGHRF---LE--------EKKVR---FCKACD---AVI--MGRKVHPIGFRLG--YI-KDWQSKWFA------E-R T--YTDQLHEDLALRKLI--AKELQ-----NAGVSRIEIERSA-N-KVEVTVYTAKPGIVIGKRGANVDLLKNNLEQKIK LNIQEIHQ---PELDAQLVAESIAEQITKRVSYKRAMKQAVQRAMRL-GALGVKVRCSGRLGGAEMSRIQNESEGRVPR- -HTLRADIDYAQVHAHTTYGRIGVKVWIY--------------------------------MKLAIADILKREGFIKDYT LVE----G---K----PFSSIAITLKYM---SDR-------R---PAITGLRRVSKPGLRIYTKRDEIPQVRGGLGLSIL STPKGILAGHEAWREHVGGEVLCYVWMAKQKVRIRLKAYDHKILDQSARQIVEAAERTGALVAGPVPLPTKIEKYSVIRS GFIDKNSQ-EQFEIRTHKRLIDVLDPSQQTINALMKLNLPAGVDIEIKLKIVKVGRVVSDKMDKTVVVAVDYLKPHPLYR KIIRKTNKFHAHDEE--NTCKVGDLVRIEESRPLSRTKRWKVVEIVQRG------------------------------- -MARSS-KKGPYVDI-RLLDRVEAMNR---TNDKR----VLRTWSRDSTIFPQMIGHTIAIHDGRRHVPVYVTE-NMVGH KLGEFAPTRFFRGHG------GKKADK----RGK------MK >CHLOFL_Roseiflexus_castenholzii_DSM_13941 Concatenation of 2 sequences MPVRKYKPTSAGRRNMSVSTFEE-ITKK------------EP-ERSLLEPLRKKAGRNVYGRITVRH-RGGGHKRH---- YRKIDFK-R--DK-VGIPAKVAAIEYDPNRSARIALLHYV-DGEKRYILAPLGLNVGDTVMSGP-A-AD-IRVGNALPLR QIPLGTQVHNIELEKGRGGVMVRSAGAAAQLMAK--EGNYATLRMPSGEVRRVFIECMATIGQVGNLDHQNVRLGKAGRK -RWL-----GRR-P-EVRGAAMNPRDHPHGGGEGRA-P--RGMPTPKTK---WGKPARGVKTR-HNPR-TD-A-FIIRRR --------------------------------MIE---G-LLGRKIGMTQVFD-PTGQ---------VIPVTIIEVGPCV VTQIR----TKE----R--DGY--EAVQIGY-------QE--VLTK----------PEQGHL------------------ ---RGAGKLLRHLREFRT--------DNIADH-----KV---GD-VLTV--E-M-FAPGQRVDVIGTSKGRGFQGVVKRH GFGG-GPRTHGQSDRLRA-PGSIGAG-TDPG-HLWKNTRMAGRMGNQRVTVQNLTVVDVVPERN---------------- ----------LLLVRGS-VPGANNGLVMVR--MEAKLYN-QSGEEV-GVIQISDYVF----GI-EP-NVPVMHQAMERQR ANARLGTHNTLGRGE--------VE-GSTRKLY---------RQKGTGRAR--------QGS---IR-AP----HR---- KGGGIAHGPH-P-RSYTKDMPRKMRRLAVRSALSARHRDG----------------A-ILFLDRL----TFE-Q------ --PRTKLIV--LDRKD--E---HVRRSANNLPNVK-T---------------LLAHYLNVIDLLTHDH----VVMLKAAV DVAQPRLKEKYQTEV----VPALMQEFQYRSVMQAPRLEKIVLNIGLG-EAIQNSKALDAATSDLAAIAGQKPVITRARK SIAAFKVRQGMPIGVMVTLRGPRMWSFFDRLVNLVLPRLRDFRGVSR-RSFDGRGNYSLGLREQIVFPEID-----YDKV DKLRGLEVVIVTT-----------------------APDDEQGYALLKRLGMPFMSRIG-K--KPIPVPRGVEVT-I--- -A-E-GN-VVTVKGPKGTLIQRL--PP-E--MIITHEN-GV--ITV---AR-L--SDQKQHR-ALHGLTRSLIANMVTGV TEGYQRVLEITGIGY--RAVREG-KN--LILQ--VGFSHPIRVTP-P-E-GITFEVN--E-PQQVIIRG-IDKQKVGEEA AKLRALR------PPEPY---KGYGIKYREERVRRKAGK----------MVQQETRLRVADNTGAKEILCIRVLG-SHVR Y--GRVGDVIVASVKEATPG-G-------AVKKGEVVRAVIVRTAKEYGRPDGSHIRFDDNAAVIIG-KDNN-PRGTRIF GPVARELR-ERAFMKIISLAPEVLMK-L--HDLKPALGA-HRKRKRIG-RGIGSGK-GKTGGKGMMGQKARSGPN-P--- -SPSF-E-GGQMRITRKMPKLRG--FKNINTGQLLTINAMIEQ-GWVQVK---------ILG--DGE-L-E-R-K-LTI- HAHKFSASARARIEAAGGAA-K---QQR--GHN---RGMA-HRGNTVAFG----------EYGLMAI--EATWMTSRQIE AARRAISHHV------KRGGKIWIRIFPDKPVTAKPAETRMGSGK---------GAVDHYVAVIKP-GRILFEL--AG-- VRPEIAHEALERAAQKLPIKCKI-VPRELRLRRHRRVRKKV---SGTPQRPRLCVFRSNMHIYAQVIDD---T--VGRTL AAASTV-EPEL-RASL----AGK-TKTERAKVVGAAIAER--ARAVG-IECVVFDRGGFKYH--GRIQALADAAREGGLK F--------------------------------------------------------------MQ-AKAVTKYVRISPTK VRPVMDLVRGKPVDRALAILRYL---------------------------------PHKAAREIARTIESARAN----A- TNNY-DMAPDALVVKYIFADEGPAFKRIMPRARGRADRIRKRTTHITVIVDD-MHVKTGDEVLIITGK------DR-GKR GKIKESRPKEQ--RVI--VEGLNIVKRHMK----PR--GP-TRP-GGIIEMEAPIHVSNVM-LICPKC-------GR--A --SRTGHRF---LE--------ETKVR---YCKACD---AVI--MGRKVHPIGFRLG--YI-KDWQSKWFA------E-R N--YTELLHEDVMLRKII--AKELE-----NAGVARIDIERSA-N-KVEVTVHTAKPGIVIGKRGAKVDELREELARRVK LNIQEIHQ---PELEAQLVAESIAEQINKRVSYKRAMKQAVQRAMRL-GAQGVKIKCSGRLAGAEMARIAWERDGRVPL- -HTLRADIDYAQVHAHTTYGRIGVKVWIYMSVNDPIADMLTRIRNACMARHATVSI-PSSKMKLAIAQILKREGFIQDFT VQE----G---K----PYSTIVITLKYT---PDR-------R---PVITGLKRVSKPGLRIYTKRADIPRVRGGLGLSIL STPRGVMAGHEAWQQRVGGEVLCYVWMAKQKVRIRLKAYDHKILDQSARQIVEAAERTGALVAGPVPLPTKIEKYSVIRS PFIDKDSQ-EQFEIRTHKRLIDVLDPSQQTINALMKLNLPAGVDIEIKLRQFKVGRVVSNKMQKTVVVAVDYLKPHPLYR KIVRRTSKFHAHDEQ---QCQIGDVVRIGETRPLSKTKRWEVVEIIKRN------------------------------- -MSRSS-KKGPYVDV-RLLGRIEELNR---ANEKR----VLRTWSRDSTIFPQMVGHTIAVHDGRRHVPVYITE-NMVGH KLGEFAPTRLFRGHG------GKKVDK----RGK------MK >CHLOFL_Roseiflexus_sp_RS-1 Concatenation of 2 sequences MPVKKYKPTSPGRRNMSVSTFEE-ITKK------------EP-ERSLLEPLRKKAGRNNYGRITVRH-RGGGHKRH---- YRRIDFK-R--DK-IGVPAKVAAIEYDPNRSARIALLHYV-DGEKRYILAPLGLNVGDTVMSGP-D-AD-IRVGNALPLR QIPLGTQVHNVELEKGRGGVMVRSAGAAAQLMAK--EGNYATLRMPSGEVRRVFIECMATIGQVGNLDHQNIRLGKAGRK -RWL-----GRR-P-EVRGAAMNPRDHPHGGGEGRA-P--RGMPTPKTK---WGKPARGVKTR-HNPR-TD-P-FIIRRR --------------------------------MIE---G-LLGRKIGMTQVFD-ATGQ---------VIPVTIIEVGPCV VTQIR----TKE----R--DGY--EAVQIGY-------QE--VLTR----------PEQGHL------------------ ---RGAGKLLRHLREFRA--------DNIADH-----KV---GD-VLTV--E-M-FTPGQRVDVIGTSKGRGFQGVVKRH GFGG-GPRTHGQSDRLRA-PGSIGAG-TDPG-HVLKNTRMAGRMGNQRVTVQNLTVVDVVPERN---------------- ----------LLLVRGS-IPGAKNGLVMVR--MEARLYN-QSGEEV-GVIQISDYVF----GI-EP-NVPVMHQAMERQR ANARLGTHNTLGRGE--------VE-GSTRKLY---------RQKGTGRAR--------QGS---IR-AP----HR---- KGGGIAHGPH-P-RKYTKAMPRKMRRLAVRSALSARYRDG----------------A-ITFLDRL----TFE-K------ --PRTKLIV--LDQKD--E---YVRRSANNLPNVK-T---------------LLAHYLNVIDLLTHDH----IVMLQAAV DVAQPRLKEKYQTEV----VPALMQEFRYRSVMQVPRIEKIVLNIGLG-EAIQNSKALDAATADLAAIAGQKPVITRARK SIAAFKVRQGMPIGVMVTLRGPRMWSFLDRLMNLVLPRLRDFRGVSR-RSFDGRGNYSIGLREQIVFPEID-----YDKV DKLRGLEVVIVTT-----------------------APDDEQGYALLKRLGMPFMSRIG-K--KPIPVPRGVEVT-I--- -T-E-EN-RVTVKGPKGTLSQQF--SP-E--MLITHEN-GV--ITV---AR-P--SDDKRHR-ALHGLTRSLIANMVTGV TEGYQRILEITGIGY--RAAREG-KN--LVLQ--VGFSHPIRVTP-P-E-GITFEVN--E-PQQVIIRG-IDKQKVGEEA AKLRALR------PPEPY---KGYGIKYRDERIRRKAGK----------MVQQETRLRVADNTGAKEILCIRVLG-SRVR Y--GRVGDVIVASVKEATPG-G-------AVKKGEVVRAVIVRTAKEYGRPDGSHIRFDDNAAVIIG-KDNN-PRGTRIF GPVARELR-ERAFMKIISLAPEVLMK-L--HDLKPAPGA-HRERKRIG-RGIGSGK-GKTGGKGMMGQKARSGPK-P--- -SPSF-E-GGQMRITRKMPKLRG--FKNINIGQLLTIEEMVAQ-GWIHVK---------ILG--DGE-L-E-R-K-LTI- HAHKFSASARARIEAAGGAA-K---QQR--GHN---RGMA-HRGNTVAFG----------EYGLMAL--EATWMTSRQIE AARRAISHHV------KRGGKIWIRIFPDKPVTAKPAETRMGSGK---------GAVDHYVAVIKP-GRILFEL--AG-- VRPEVAHEALERAAQKLPIKCKI-VPRELRIRRHRRVRKKV---HGTPQRPRLCVFRSNMHIYAQVIDD---T--VGRTL AAASTV-EPEL-RASL----TGK-TKTEQAKAVGAVIAER--ARAAG-IERVVFDRGGFKYH--GRVQALADAARAGGLQ F--------------------------------------------------------------MQ-AKAVTKYVRISPTK VRPVMDLVRGKPVDRALAILRYL---------------------------------PHKAAREIARTIESARAN----A- TNNY-DMAPDALIVKYIFADEGPAFKRIMPRARGRADRIRKRTTHITVIVDD-MHVKTGDEVLIITGK------DR-GKR GKIKEARPKEQ--RVI--VEGLNIVKRHMK----PR--GP-TRP-GGIIEMEAPIHVSNVM-LICPTC-------GR--A --SRTGHRF---LE--------ETKVR---YCKACD---AVI--MGRKVHPIGFRLG--YI-KDWQSKWFA------E-R N--YTELLHEDVMLRKII--AKELE-----NAGVARIEIERSA-N-KVEVTVYTAKPGIVIGKRGAKVDELRAELEKRVK LNIQEIHQ---PELEAQLVAESIAEQINKRVSYKRAMKQAVQRAMRL-GAQGVKIKCSGRLAGAEMARVAWERDGRVPL- -HTLRADIDYAQVHAHTTYGRIGVKVWIY--MHDPIADMLTRIRNACMARHATVSI-PSSKMKLAIAQILKREGFIQDFT VQE----G---K----PRNTIVITLKYT---PDR-------R---PVITGLKRVSKPGLRIYTKRADIPRVRGGLGLSIL STPRGVMAGHEAWQQRVGGEVLCYVWMAKQKVRIRLKAYDHKILDQSARQIVEAAERTGALVAGPVPLPTKIEKHSVIRS PFIDKDSQ-EQFEIRTHKRLIDVLDPSQQTINALMKLNLPAGVDIEIKLRQFKVGRVVSNKMQKTVVVAVDYLKPHPLYR KIIRRTSKFHAHDEQ---QCRIGDIVRIGETRPLSKTKRWEVVEIIKRN------------------------------- -MSRSS-KKGPYVDI-RLLNRIEELNR---ANEKR----VLRTWSRDSTIFPQMVGHTIAVHDGRRHVPVYITE-NMVGH KLGEFAPTRSFRGHG------GKKADK----RGK------MK >CHLOFL_Sphaerobacter_thermophilus_DSM_20745 Concatenation of 2 sequences MGIRRYKPTSPGRRNMTVSTFEE-ITKR------------EP-EKSLLEPLKKHAGRNNQGRVTARG-RGGGNKRF---- YRRIDFK-R--NK-FGIPAKVAAIEYDPNRSARIALLHYV-DGEKRYILAPLGLKVGDIVQSGS-G-SP-IRVGNALPLS DIPTGTPIHNIELYPGRGGQLVRSAGVAAQIMAK--QDGYAQVRMPSGEVRMIRLNCMATLGQVGNVDHENVRIGKAGRS -RHL-----GRR-P-ITRGSAMNAADHPHGGGEGKA-P--IGGQ-PRTP---WGKPTLGYRTR-RNKK-TD-K-FIVRRR --------------------------------MIH---G-LLGKKLGMTQIFN-EAGQ---------AIPVTVLEVGPCV VTQVK----TRE----R--DGY--EAVQLGF-------GH---LNQ----------PERGHLR----------------- ---AS-GAQPRYLREVKA--------DNIEEY-----SV---GQ-VIDC--S-V-FKEGERVDVTGTSKGRGFAGVMKRH GFGG-GPATHGQSDRKRA-PGSIGAS-ATPG-RVFKGLRMAGHMGNQRVTVQNLEVVRVDPERN---------------- ----------VVLVRGS-VPGANGQLVLVR--MQVPVYD-VTGQET-GQIELADSVF----GI-EP-NVPVMHQAYVRQM ANARLGTHDTKTRGE--------VR-GGGRKPW---------RQKGTGRAR--------HGS---IR-SP----LW---- RGGGVVFGPH-P-RKYTQRMPRKMRRLAIRSVLSAKMKAD----------------Q-VVVVEGL--T-ELE-------- --PRTKLIL--VDEPR--E---NLRRGANNLEHVR-V---------------LPAQYVNMRDVLKYER----LLLTREAV DVIHARLRELYRNEI----VPKLMAEFGYRHVHEVPRLEKIVLNIGLG-EAIHNGRALDAAADDLATITGQRPVVTRAKR SIAGFRLRAGMPIGVMVTLRGDRAYEFLDRLIGTALPRIRDFRGLSP-RSFDGRGNYTLGLREQLVFPEID-----YDKI DKVRGLEVTIVTT-----------------------AKTDEEGRRLLALLGMPFMSRIG-N--LPIPIPAGVEVQ-I--- -DSG----VVRVKGPKGELEQRV--HP-A--MRFERES-GT--LLV---RR-P--SDERQFR-ALHGLTRTLVANMVHGV TEGYRKDLEIHGVGY--RAQLEG-KT--LVLS--LGFSHPVRIDP-P-E-GITFVLE--S-PTRIGVQG-IDKQLVGEIA ARIRRVR------PPEPY---KGKGVRYLGERVRRKAGK----------MIQQESRLKVADNSGAREILCIRVLG-SGRK Y--ASVGDVIVATVKSAQPN-S-------AVKKGDIVRAVVVRTAQEYGRPDGTHIKFDDNAAVLIN-QQGN-PRGTRIF GPVARELR-DRQFMRIVSLAPEVLMQ-L--HDLKPAPGS-RKERTRVG-RGDGSGK-GKTAGRGTKGQKARGT---V--- -RRGF-E-GGQNPIYKRLSYRRG--FVNVNVGRLITPEVLYER-GVTRVK---------ILG--DGE-V-T-R-P-LTV- RAHKFSKSAREKIEAAGGTV-K---VQR--GRM---TGQA-SRGNTVVFG----------EYGIQAL--EPAWVTSRQIE AARRAITNYV------RRGGKVWIRIFPDKPVTQKPAETRMGSGK---------GNPEYWVAVVKP-GRVMFEL--GG-- VREELALEALRRAIHKMPMKCRV-VTLSPRKRRHLRVRAKV---SGTPERPRLNVFRSNEHIYAQVIDD---T--VGHTL VAASTL-EKAV-RERF----PEEHPKVVEARIVGMVVGER--AREKG-ITRVVFDRGGYKYH--GRVRALAEAAREAGLE F--------------------------------------------------------------ME-VMAKARGLRVSPRK ARLVVDMVRGKSVPEALAILRFV---------------------------------PNKSAEYVAKVVKSAAAN----A- EHNH-DLDPDRLYIKQIYADEGPTYRRWRARARGRVNRRLKRTAHITVIVDEAEKIVTGDEVLVIRGR------DK-GAR GRVRQNMPRVD--RVI--VEGVNRVKKHQR----AL--PG-GRP-GGIIEVEAPLHVSKVM-LICPSC-------DK--A --TRVGFRF---TE--------SGKVR---YCKKCD---AVI--MGRKVHPIGFRLG--IV-HDWESKWYA------E-R N--YTEQLHEDLTIRRLI--NAELT-----RAGISRIEIERAA-N-RIEVTIHTSKPGIVIGKQGANVERIRQLIEQQVH LKIEEIKD---PELDARLIAESIAEQISRRVSFRRAMKHAATQAMRK-GAKGVKIRLSGRLGGAEMARTVTEMMGRVPL- -HTIRADIDFAVVHAHTTYGRIGVKVWVYMTINDSIADMLTRIRNAGMARKPETSM-PSSKILVAIARILKEEGYIEDFR VEE----R---R----PYPVLTIKLKYT---RDR-------R---HAIRELRRISKPGLRVYAGKDEIPRVRNGLGIAIV STPQGVMSGHEARRRGIGGEVLCTVFRPTQKIRIRLKAYDHKILDQSAAKIVDTAESTGAKVSGPVPLPTRIERFSVIRS PFIDKDSQ-EQFEIRTHKRLIDVLEPSHATIRALMRLNLPAGVDIEIKLRLTKVGRVVSDKMDKTVVVSVDYLRRHPLYR KTIRRTSKFKAHDEH--NRCKVGDLVLIEETRPLSKTKRWIVREILERA------------------------------- -MGRSS-KKGPYIDP-KLREKIQQANA---SGDRR----VIRTWARDSTIFPEMIGHTVAVHDGRRFVPVFVTE-QMVGH KLGEFAPTRTYRGHG-------KDAER----SSR------RR >CHLOFL_Thermomicrobium_roseum_DSM_5159 Concatenation of 2 sequences MPIKVYKPTTPGRRNMSVLTYEE-ITKE------------AP-EKSLIEPLKKHAGRNNRGVITTRH-RGGGNKRF---- YRIIDFR-R--DK-WGIPAKVAAIEYDPNRTAFIALLHYA-DGEKRYILAPLGLKVGDIVQSGP-G-AP-IRVGNALPLR EIPLGTQVHNVELYPGRGGQLVRAAGAVAQVVAK--IDNYVHLRLPSGEIRMVHADCMATIGQVGNLDHQNVSIGKAGRK -RHM-----GWR-P-AVRGSAMTPRDHPHGGGEGKA-P--RGMP-PKTP---WGKPALGKRTR-RNKK-SD-R-FIIRRR --------------------------------MIE---G-LLGRKLGMTQIFD-DEGR---------AIPVTVLEVGPCV VTQVK----TSD----R--DGY--QAVQLGF-------GH---QNR----------PMQGHLR----------------- ---AS-GASPRYLKEVRV--------DDATRF-----QV---GQ-VIDC--T-I-FQPGQLVDVIGWRKGRGFQGGVKRH GFAG-GPKTHGQSDRHRA-PGSIGPT-TDPG-RVHKGKRMAGRMGPVRVTVQNLRVERVDPQRN---------------- ----------LVLVRGA-VPGHPNGLVIVR--MQVPVYD-LEGRAV-DQIELADSVF----GI-TP-NIPVMHQALVRQL ANARAGTHDTKTRGE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----HW---- KGGGVVWGPH-P-RSYRQEMPKKMRRLAIRSLLSVKQREN----------------Q-IVVVRGL---TDIE-------- --PKTKLIV--VDQRD------NVRRAAGNLEDVK-V---------------LVAHNMNIRDGLKYER----MILTPEAV EVIHPRLKRLYREEV----VPTLMEEFGYPHRLAVPRLEKIVLNIGLG-EAVSNQKAIDHAMNDLAAITGQRPVVTRARK SIAAFRLRKGMPIGVMVTLRGNRMWDFLDRLIAIALPRIRDFRGVSP-KSFDGRGNYTLGLREQLVFPEVD-----YDKI DKVRGLEVTIVTT-----------------------ARTDREARRLLELLGMPFMSRIG-K--RPIPIPAGVQVE-L--- -T-P-DN-VVRVTGPKGQLELRL--HP-K--MIVQREN-GV--VQV---QR-P--SDERFFK-QLHGLYRTLIANMVQGV TEGFRKDLEIHGVGY--RAALEG-KT--LVLT--VGYSHPVRIDP-P-P-GISFIVE--S-PTRIGVVG-IDKQLVGEVA AQIRRVR------PPEPY---QGKGIRYAGEVIRRKAGK----------MIQPLSKLVVADNTGAKEIMCIRVLG-SKHR Y--GTVGDLIVASVKKAEPN-A-------AVKKGDVVYAVIVRTKKEYRRKDGSYIKFDDNAAVLVT-PQGQ-PRGTRIF GPVARELR-EKHYMRIISLAPEVWMK-L--HELKPAPGS-RRPKTRVG-RGIAAGK-GKTAGRGTKGQKARSK---V--- -RPGF-E-GGQNPLYLRLGRMRG--FKNVNVGRLITPDVLRSF-RLVRVK---------ILG--DGD-V-T-R-P-LHV- QAHAFSESARQKILAAGGTV-K---QHR--YRT---KGIA-WRGSTLAFG----------DYGIQAL--EPAWVTAQQIE AARRAITNAV------RRGGKVWIRVFPDKPVTKKPAETRMGSGK---------GNPEYWMDVVKP-GRILFEL--AG-- VREELALEALTRAIHKLPCRCRI-VRLSPRKRRHLRVRAKV---FGTPERPRLNVFRSNKHIYAQIIDD---T--RGHTL VAASTL-EKEV-RERF----PDPHPKIEEARIVGQVVGER--ALAKG-ITRVVFDRGGYKYH--GRVKALADGARAAGLQ F--------------------------------------------------------------ME-VRAMVREVRVSPQK ARMVIDVIRGKPLRDALAVLQVL---------------------------------PQKTAPIALKLLRSAAAN----A- EHNY-DLDPDRLYVKRIYVDEGPRYKRWQPHARGRVGRKWRRTSHITVILDEAEKIVTGDEVIVIRGK------DR-GAR GRVRQNLPRED--RVI--VEGVNIVKKHQR----AI--PG-VRQ-AGIIEMEAPIHVSKVM-LICPHC-------GK--P --TRVGFRF---TE--------TGKVR---YCKKCQ---QVI--MGRKVNPIGFRLG--IV-HDWESKWFA------E-K DRQYREQLHEDLDIRELV--HRELP-----RAGISRIEIQRAV-N-RVDVTIHTAKPGVVIGKQGANVERLRQLLESRVH LNIQEIRK---PELDARLVAESIAEQITRRVSYRRAMKHAAAAAMRA-GAKGVKIRVKGRLGGAEMKRMVWEIVGRVPL- -NTIRANIDYAVVHAPTIYGQIGVKVWIYMTITDPIGDMLTRIRNAGMGRKAEATM-PASKMLVEIARILKEEGYIADYA VEP----A---S----PRPILRIRLKFT---PDK-------R---PVIREIKRVSKPGLRIYVGKDEIPRVKGGLGIAIL TTSQGVMTDAEARRRGIGGEVICTVFRPTQRIRIRLKSHDHRILDQSARQIVETAESTGAKVAGPIPLPTRIERFTVIRS PFIDKDSQ-EHFEIRTHKRLIDVLEPSPSTIRALMRLTLPAGVDIEIKLRLTKVGRVVSDKMDKTVVVAVDYWRRHPLYK KTVRRTSKFYAHDEY--NLCRIGDLVLIEETRPISKLKRWVVRQILERA------------------------------- -MGRSS-KKGPYIDP-KLKKKIDELNR---TGERR----VIRTWARDCTIFPEMVGHTIAVHDGRRHVPIYITE-QMVGH KLGEFAPTRTYRGHG-------KDAER----TTR------RR >CYANO_Acaryochloris_marina_MBIC11017 Concatenation of 2 sequences MGIRYYRPYTAGTRQKTSSDFAE-ITRD------------RP-EKSLVKAKHRAKGRNNRGVITSRR-RGGGHKRR---- YRIIDFY-R--NK-LGVPGTIATVEYDPNRNARIALVNYK-DGEKRYILHPRNVQVGTTIVAGP-D-AP-IEVGNALPLE RIPLGTEVHNVELIPGKGGQLARAAGALAQVVAK--EGKMVTLKLPSGEVRLFQKECYATIGQVGNVESNNITIGKAGRN -RWK-----ARR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGYKTR-KKKKQSN-K-LIVRRR --------------------------------MSV---G-ILGTKLGMTQVFD-EAGR---------AIPVTVVQAGPCP VTQIK----TAQ----T--DGY--TAIQIGY-------GS--TLTR----------PELGHLK----------------- ---SG-STPVRHLQEYRL--------ADVSEY-----EL---GQ-SISA--D-L-FSEGQLVDISGTSIGRGFAGYQKRH NFRR-GPMGHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGQMGNVKKTIRKLTVVRVDAERN---------------- ----------VLLIKGS-VPGKPGALLNIQ-MVNCVVRN-WQGEDA-GQAELDLKVA----NE-EN-AAHIVHRALRRQM NNARQGTASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---SR-SP----LW---- RGGGVIFGPK-P-RSYSTKMNRKERRLALRTAFASRAED-------------------LVVVEDF--GDNLS-R------ --PKTKLLI--LADKH--D---TIYLSARNVEKLK-L---------------ILASNLNVYDLLAADQ----IVATQSAI AKIQVRLKTLYLDTA----VPKLQEQFKYKNAHEIPKVTKVSVNRGLG-EASQNAKALERSLEELAVITGQRPVVTRAKK AIAGFKIRQGMPVGVMVTLRGERMYAFLDRLVNLALPRIRDFRGVSP-KSFDGRGNYTLGLREQLIFPEVD-----YDSI DQIRGMDISIITT-----------------------AKTDEEGRALLKVLGMPFMSRIG-K--VPIPIPDKVNVT-I--- -K-G--Q-AVTVKGPKGELSREI--TP-E--VAIEQAD-NL--VTV---TR-R--NESRIAR-QRHGLSRTLIANMVEGV SKGFEKKLQIQGVGY--RAQVQG-RN--LILN--VGYSNPVTIEP-P-E-GVQVAVE--S-NTNVIVSG-INKEVVGNTA ARIRAVR------PPEPY---KGKGIRYADEYVRRKVGK----------MIQQETTLNVADNSGAKRLLCIRVIG-GNRR Y--GGVGDVIIATVKDATPN-M-------PVKKSDVVRAVIVRTRKSICRESGMSIRFDDNAAVLIN-PDGN-PRGTRVF GPVARELR-DKSFTKIVSLAPEVLMR-L--NDPKPKTGS-QHRRRRVG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQNPLYRRVPKLKH--FTLINVGKLVTLESLMAE-GIITLK---------VLG--DGE-L-T-V-A-LNV- QAAAATQSAIAKVEGAGGSF-K---QHR--GRM---RGKA-TRGNTLSFG----------DYGLQAL--EPSWITSRQIE AGRRAMTRYV------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GAPEYWVAVVKP-GRIMYEM--NG-- VPESTAREAMRLAAFKMPIKTKF-VRRDATRSRHQRVRRKV---VGTAERPRLAVFRSNQHIYAQVIDD---A--QQHTL AAASTV-ESDL-KS------SSG-ATCDASTAVGKLVAER--AIEKG-IKAVVFDRGGNLYH--GRVKALADAAREAGLE F-------------------------------------------------------------ING-AYAKAKYIRMSPRK VRRVLDQIRGRSYREALIVLEFM---------------------------------PYRACEPVLKVLRSAVAN----A- ETNR-GLDPVDLVVSHAYADQGPRLKRFRPRAQGRAYQIQKPTCHITIAVSAKMHVKKGDTVQVIAGK------DK-AKV GEVIDVLPKLS--QVV--VEGVNMKTKHVK----PR--SE-SES-GQISTVEFPIHSSNVM-LYSNKE-------NV--A --SRVCYTF---DD--------SGKVR---MLKKTG---EII--MGQKIHPTGFRLG--IT-QDHWSRWFA------DTD R--YPELLQEDFKVRNYV--NKNLS-----NAGIAGVRIERKA-D-QIDLEVRTARPGVVVGRGGSGIESLRVGLQKEIR INVVEVAR---VDAEATLIAEYIVQQLVRRVSFRRVVRQAIQRAQRA-GVEGIKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRANIDYSYRTASTTYGILGVKVWVFMAANDTIGDMLTRIRNANLARHQTTQV-MSTRMTRSVASVLKDEGFITSFE ESG----E---G----VERRLVITLKYR--GKNR-------Q---PIINTLQRISKPGLRVYSNRRDLPRVLGGIGIAII STSSGIMTDRDARQTGVGGEVLCYVWLQQQKIRIRLKAFDHRLLDTSCDKIVETAKRTNASPVGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHRRIVDIYQPSPKTIDALMKLDLPAGVDIEVKLIKERIGVVVSDKMDKTVVVAVSNRVPHKKYG KIVGQTRRYKAHDEE--NACHVGDRVRIRESRPLSRTKRWAVTDVLVAA------------------------------- -MSRSL-KKGPFVAD-HLLTKVENLNE---KGEKQ----VIKTWSRASTIIPQMIGHTIAVHNGRQHVPVYVSE-QMVGH KLGEFAPTRTFKSHS------KG--DK----KAR------M- >CYANO_Anabaena_variabilis_ATCC_29413 Concatenation of 2 sequences MGTRSYRPYTPSTRQVTISDFAE-ITKT------------EP-EKSLTVYKHRAKGRNNQGRITSRR-RGGGHKRL---- YRIIDFK-R--DK-RSIPATVIAIEYDPNRNARIALVSYE-DGEKRYILHPNNLKVGTVIIAGP-E-SP-IEDGNALPLA NIPLGTSVHNVELKAGKGGQIVRSAGATAQVVAK--EGNYVTLKLPSGEVRLIRRECYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGAKTR-KPKKASS-K-LIIRRR --------------------------------MSV---G-ILGTKLGMTQIFD-EAGV---------AIPVTVVQVGPCV VTQVK----SKQ----T--DGY--AAIQVGY-------GE--VLNR----------PLLGHLK----------------- ---SS-APALRHLKEYHT--------DSSSDY-----AL---GQ-EIKA--D-I-FSAGELVDVIGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHRA-PGSIGAG-TTPG-RVYPGKRMAGRLGGTRVTIRKLTVIRVDAERN---------------- ----------LLLIKGA-VPGKPGSLLSIV-MVESVVKN-WQGEQV-GQKTFELRVA----KE-TT-AAHIVHRALVRQQ TNARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFDLKMNRKERRLALRTALVSRIDD-------------------LILVEEF--SNELS-R------ --PKTKLLI--LSEFP--E---NVYLSARNIENLK-L---------------IAADQLNVYDLLHADK----IVVTTSAL EKIQTRLKTLYQETI----IPKLTQQFQYTNVHQVPKLVKITVNRGLG-EAAQNAKSLEASLTEIATITGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRGERMYAFFDRLISLSLPRIRDFRGISP-KSFDGRGNYTLGVREQLIFPEIE-----YDSI DQIRGLDISIITT-----------------------AKNDEEGRALLKEFGMPFMSRIG-K--RPITVPAKVQVT-I--- -D-G--T-KVVVKGPKGELSREL--PV-N--VSVSQEG-ET--LQV---TR-R--DETRTSR-QLHGLSRTLVANMVEGV SQGFQRRLEIQGVGY--RAQVQG-RN--LILN--MGYSHQVQIEP-P-D-GIQFAVE--N-NTNVIVSG-YDKEIVGNTA AKIRAVR------PPEPY---KGKGIRYAGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLA-GNSR Y--GFIGDKIIAVVKDATPN-M-------AVKKSDVVEAVIVRTRHHIRRDSGMTIRFDDNAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--NDVKPQKGS-KKRRRRVG-RGISAGQ-GASAGLGMRGQKSRSGSG-T--- -RPGF-E-GGQQPLYRRIPKLKG--FPVINVEKLVTLESLRAS-GILTLK---------VLG--NGD-L-G-V-A-LNV- KAAAFTGQARSKIEAAGGSC-K---QQR--GRM---GGLA-HRGSTLNFG----------DFALQAQ--EPAWITSRQIE ASRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEI--AG-- VTEEIAREAMRLAAYKLPIKTKF-IRRESKQRRHRRVRGKV---QGSPERPRLAVFRSNEHIYAQVIDD---T--QHHTL VSASTV-EPEV-KSSL----ASG-ANCEASSQIGKLIAVR--SLEKG-ITKVVFDRGGNLYH--GRIKALAEAAREAGLD F-------------------------------------------------------------TTE-VKAIARFIRMSPYK VRRVLDQIRGLSYREALIILEFM---------------------------------PYRATEPVLTLLRSAAAN----A- EHNA-GLDRAELVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITLAVAAKLHVKTGDTVQVIAGK------DK-GKV GEVIKALPQLS--KVI--VKGVNIKTKHVK----PQ--QE-GES-GRIVTQEAPIHSSNVM-LYSTKQ-------NV--A --SRVCYTF---TA--------EGKVR---KLKKTG---EIL--MGQKIHPVGFRLG--IT-QEHQSRWFA------EPS R--YPELLQEDHKLRQYI--EQKLGRLAQNNAGISEVRIERKA-D-QIDLEVRTARPGVVVGRGGQGIEALRTGLQTLIR INVVEVQR---VDADAYLIAEFIAQQLERRVSFRRVVRQAIQRAQKA-GIQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAKTVYGILGIKVWVFMAANDTIADMLTRIRNANMARHQTTLV-PATKMTRSIAKVLQEEGFIAEIS EEG----D---E----VKRNLVIALKYK--GKNR-------Q---PLITALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGIMTDREARRQNLGGEVLCYVWLQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKLIKERVGLVVSDKMQKTVVVAIENRAPHPKYG KIVVKTRRYKAHDED--NKCKVGDRVRIQETRPLSKTKRWQVAEILNTK------------------------------- -MGRSL-KKGPFIAD-HLLSKIEKLND---KNEKQ----VIKTWSRASTILPLMVGHTIAVHNGRQHVPVFISE-QMVGH KLGEFAPTRTYRGHG------K--SDK----KAG------R- >CYANO_Cyanothece_sp_ATCC_51142 Concatenation of 2 sequences MGIRTYRPYTPGTRQASVSDFAD-ITKP------------KP-EKSLTTYKHNKKGRNNRGVITSRH-RGGGHKRL---- YRIVDFK-R--DK-YGVPAKVAAIEYDPNRNARIALLFYQ-DGEKRYILAPAGITVGTEVISGE-D-SP-FEVGNALPLY KIPLGTEVHNIELVAGKGGQMVRAAGAAAQVVAK--EGDYVTLRLPSKEVRMVRKECYATIGRVGNTEARNIKLGKAGRT -RHL-----GRR-P-HVRGSVMNPVDHPHGGGEGRA-P--VGRSGPMTP---WGKPALGAKTR-NKKKASS-R-LIVRRR --------------------------------MAV---G-LLGTKLGMTQIFEEESGL---------AIPVTVVQAGPCT ITQIK----TAE----T--DGY--SAIQIGY-------LE--VLTK----------PELGHLK----------------- ---VE-ASPLRHLKEYRV--------DDTATY-----TL---GE-AVKA--D-I-FNAGDLVDIAGTSMGRGFAGYQKRH NFKR-GSMTHGS-KNHRL-PGSTGAG-TTPG-RVYPGKKMAGQYGAVKTTTRHLQVVRVDAERN---------------- ----------LLLIKGA-VPGKPGGLLNIT-------------------------MA----KD-ET-ASHLLHRAVVRHL ANARQGNASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFSLKMNRKERRLALRTAIGSRVED-------------------MIVVENF--AEQLP-Q------ --PKTKALV--LVETD--A---NIYLSARNLCHVK-I---------------LRADSLNVYDLLDADK----IVITSEAI SKIQPRLKTFYQETI----VPKLQQQFSYSNIHQVPKIAKITINRGLG-EASQNAKALESSISELETITGQKPVVTRAKK AIAGFKIREGMPVGVMVTLRSEKMYAFLDRLINLALPRIRDFRGISP-KSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------AQTDEEGRALLKEMGMPFMSRIG-K--KPIPLPNKVTID-I--- -K-G--Q-HIAVKGPKGSLELDL--PS-E--VTVNQEG-ET--VEV------QRVDDSRTAR-ERHGLFRTLVANMIQGV SQGFEKRLNIQGVGY--RAQAQG-SK--LTLN--VGYSKPVEMTM-P-Q-GINVAVE--N-NTQVVVSG-IDKEIVGNIA AKIRGVR------PPEPY---KGKGIRYQDEYVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLT-GNCR Y--GEIGDKIVAVVKDALPN-M-------PIKRSDIVTAVIVRTRQPVNRASGMSIRFDDNAAVIIN-ADGN-PRGTRVF GPVARELR-DKSYTKIVSLAPEVLMR-I--HEVNPQKGS-TKRRRRIG-RGISAGQ-GASGGFGMRGQKSRSGTG-T--- -KAGF-E-GGQMPLYRRVPKLKH--FPLINVGKLVTLESLMEV-GLITLK---------VLG--NGE-L-T-V-P-LTV- RAPKFTASAKAKIESAGGSC-K---QQR--GRM---RGLA-HRGSTLNFG----------EYALQAT--EPSWITSRQIE AARRAMTRYI------KRGGKIWIRVFPDKPVTMRAAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--SG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESLKRRHRRIRRKV---SGTPDCPRLAVFRSNHHIYAQIIDD---V--AQHTL AAASTL-EPDL-RNSL----SSG-ATCEASAAVGKLVAER--GMAKG-IEQVVFDRGGNLYH--GRVKALADAAREAGLQ F-------------------------------------------------------------TTE-AKAIARYIRMSPFK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPILKLLRSAVAN----A- EHNQ-GLDPTTLVVSQAYADGGPSLRRYRPRAQGRAYQIRKPTCHITIAVAPKMHVKTGDTIQVISGR------DK-GKV GEVLKTIPTTS--EVV--VKGVNVKTKHVK----PQ--QE-GES-GQIATFEAPIHSSNVM-LYSTKE-------QV--A --SRISYTF---TE--------EGKVR---MLKKTG---EII--MGQKIHPIGFRLG--VT-KEHKSCWYA------DKR R--YPELLQEDLAIRQHV--EKNLS-----NAGIADIRIERKA-D-QIDLAIHTARPGVVVGRGGSGIEQLRTGLQQTIR INVIEVSR---VDADAALIAEYITQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVGGRLNGAEIARTEWVREGRVPL- -HTLRADIDYAYRTAQTIYGILGVKVWVFMAPNDIISDMLTRIRNACAVRHPTTVV-PTTKMTRSIAQVLKEEGFIEGFE EVG----E---G----VKKHLVISLKYK---SRG-------R--QPIINTLQRVSKPGLRVYSNRKDLPRVLGGIGIAII STSKGIMTDREARRQNVGGEVLCYVWLAQQKIRIRLKAFDRRLLDTSCEKIVDTANRTDATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKERVGVVVSTKMDKTAVVAVENRSPHPKYG KIVVKTKKFKAHDPE--NQCQEGDRVRIRETRPLSKTKRWEIKTIL-TA------------------------------- -MSRSL-KKGPFIAD-SLLTKIEKLNE---KGDKQ----VIKTWSRASTIIPAMIGHTIAVHNGKQHVPIFISE-QMVGH KLGEFAPTRTFRGHS------K--GDK----KAR------R- >CYANO_Cyanothece_sp_PCC_7424 Concatenation of 2 sequences MGIRTFRPYTPGTRQASVSDFSE-ITKT------------QP-EKSLTTYKHSSQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-HNIPAKVAAIEYDPNRNARIALLYYQ-DGEKRYILAPADLKVGSTVISGE-D-AP-FEIGNALPLW RIPLGSEVHNIELVAGRGGQMVRAAGASAQVVAK--EGNYVTLRLPSKEVRMVRKECYATIGKVGNADVRNLKLGKAGRS -RHR-----GKR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRPGPVTP---WGKPALGAKTR-NRKKASS-K-LIIRRR --------------------------------MSV---G-ILGTKLGMTQIFDKETGI---------AIPVTVIHAGPCP ITQVK----TPA----T--DGY--NSIQIGY-------GE--VLNK----------PKLGHLK----------------- ---SA-STPVRHLKEYRL--------ENAADY-----QL---GD-GIKV--D-L-FKPGDLVDVAGKTIGRGFAGYQKRH NFKR-GSMTHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGRYGGTQVTIRKLTVVQIDTERN---------------- ----------LILIKGA-VPGKPGNLLSIT-MVNCVVKN-WQGDEV-GQTSLELKVA----KE-ET-ASHILHRAVVRHL ANARQGNASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---NR-SP----LW---- RGGGVIFGPK-P-RDYSQKMNRKERRLALRTALNSKAEN-------------------LIIVENF--APELP-Q------ --PKTKLLI--LSEIP--E---NISLSARNICNVK-L---------------IRADSINVYDILSASK----LVATSDAL AKILQRLKTVYYETI----VPKLKEQFNYTNIHQVPKVIKVTVNRGLG-DASQNAKALESSIAELATITGQKPVVTRARK AIAGFKIRKGMPVGVMVTLRSERMYAFLDRLISLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEID-----YDKI DQIRGMDISIITT-----------------------AQTDEEGRALLTEMGMPFMSRIG-K--RPITIPNKVTVN-I--- -D-G--S-HVAVKGPKGELQRTL--PT-L--VIVEQDE-GV--LRV---VR-Q--DDSRTAR-QRHGLCRTLVSNMVEGV SKGFEKRLEIQGVGY--RAAAQG-SK--LTLN--VGYSKPVEMDM-P-S-GIGVAVE--K-NTEITITG-IDKEIVGNVA AKIRAVR------PPEPY---KGKGIRYKGEVVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLT-GNCR Y--GGIGDEIIAVVKDAIPN-M-------PVKKSDVVKAVIVRTRHPLRRASGMTIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMN-L--HELAPQKGA-TKRRRRVG-RGISAGQ-GASCGFGMRGQKSRSGTG-T--- -KPGF-E-GGQMPLYRRIPKLKH--FPLINVGQLVTLETLMDA-GLITLK---------ILG--NGE-L-T-I-P-LTI- KAAAFTKGAQEKIEAAGGSC-K---QQR--GRM---KGLA-SRGNTINFG----------DFGLQAT--EPCWITSRQIE AARRAITRYV------RRGGKIWIRIFPDKPITMRPAETRMGSGK---------GSPEFWVAVVKP-GRIMFEI--AG-- VSEEIAREAMRLAAQKLPIKTKF-VRTESVQRRHSRIRRKV---EGTPSRPRLAVFRSNNHIYAQVIDD---V--AQHTL VAASTL-DKDL-KGEF----SSG-ATCEASEAVGKLVAQR--ALAKG-IEKVVFDRGGNLYH--GRIRALAQAAREAGLD F-------------------------------------------------------------TNE-VKAIARYVRMSPYK VRRVLDQIRGRTYREALIILEFM---------------------------------PYKACDVILKLLRSAVAN----A- EHNN-GLDPTTLVVSKAYADGGPSLRRFRARAQGRAYQIRKPTCHITLFVAPKMHVKKGDTVQVISGR------DK-GKV GEVLKALPKVS--KVI--VKGVNVKTKHVK----PQ--QE-GES-GQIATFEAPIHSSNVM-LYSTKE-------KI--P --SRINYTF---TE--------DGKVR---MLKKTG---EII--MGQKIHPVGFRLG--IT-KEHKSRWFA------DKY H--YPELLQEDRKIRQYV--EKNLS-----NAGISDIRIERKA-D-QVDIEIHTARPGVVVGRGGSGIEALRVGLQNAIR INVVEVAR---VDADATLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKVQVSGRLNGAEIARTEWIREGRVPL- -HTLRADIDFAYRTAKTIYGILGVKIWVFMASNDTIADMLTRIRNACAVRHPTTKV-PTTKMTRSIAQVLKQEGFIEDFS EAG----E---G----VGKHLVISLKYK--GKTR-------Q---PIITTLKRVSKPGLRVYSPCKDLPRVLGGIGIAIV STSQGIMTDREARRQGVGGEVLCYIWLQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRRVYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMNKTVVVAIENRSPHPKYR KIVVQTKKYKAHDED--NQCKIGDRVRIQETRPLSKTKRWIVAEILNTT------------------------------- -MARSL-KKGPFVAD-HLLSKIEKLNE---KGEKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPIFISE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAR------R- >CYANO_Cyanothece_sp_PCC_8801 Concatenation of 2 sequences MGIRSYRPYTPGTREASVSDFAE-ITKT------------EP-EKSLTTYKHSRQGRNNRGVITSRH-RGGGHKRL---- YRIVDFR-R--DK-HNIPAKVAAIEYDPNRNARIALLFYK-DGEKRYILAPAGITVGTMVVSGE-N-AP-FEVGNALPLA RIPLGTDVHNIELTPGKGGQMVRAAGGSAQVVAK--EGDYVTLRLPSKEVRMVRKECYATIGRVGNVEDRNIKLGKAGRT -RHL-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGAKTR-NKKKQSS-K-LIVRRR --------------------------------MAV---G-ILGTKLGMTQIFDQETGM---------AIPVTVVQAGPCT VTQVK----TPD----T--DGY--TAIQVGY-------HE--VLTK----------AEIGHLK----------------- ---ID-APPLRHLKEYRL--------DDSSQY-----QL---GD-AIKA--D-I-FNPGDLVDVSGKSMGRGFAGYQKRH NFKR-GNMTHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGQYGATQVTIRHLTVVRVDSDRN---------------- ----------LILVKGA-IPGKPGTLLNIT-MVNCIIKN-WQGEEV-GQATLELKVA----KE-EN-AAHIVHRALVRQQ TNARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVTFGPK-P-KDFNVKMNRKERRLALRTALDSRIED-------------------LIVVENF--AEQLT-Q------ --PKTKVLI--VSEIT--D---NIQLSARNVPYIK-L---------------LKADGLNVYDLLVADK----IVATAEAL SKVQQRLKQVYQDTI----VPKLTEQFSYKNPHEVPKVVKITVNRGLG-EASQNAKALESSINELSTITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSDRMYAFLDRLINLALPRIRDFRGISA-KSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITT-----------------------AQTDEEGRALLKELGMPFMSRIG-K--RPIPIPNKVTID-I--- -Q-G--Q-HVAVKGPKGSLERTL--PD-K--VNVVQEN-DT--LLV---QR-E--DDSRTAR-ERHGLTRTLVANMVEGV SKGFEKRLSIQGVGY--RAQVQG-TK--LTLN--VGYSKPVEMTM-P-A-GIQVAVE--N-NTLVIVSG-IDKEIVGNVS AEIRAVR------PPEVY---KGKGIRYSDEFVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLT-GNCR Y--GEIGDVIIAVVKDAIPN-M-------PIKRSEIVRAVIVRTRQPVRRASGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMR-I--HEVTPKEGS-TKRRRRVG-RGISAGQ-GASCGFGMRGQKSRSGTG-T--- -KAGF-E-GGQMPLYRRIPKLKH--FPLINVGKLVTLESLMEQ-GIITLK---------VLG--DGT-L-T-K-A-LTV- KAAAFSKSAQEKIAATGGSW-K---QQR--GRM---RGMA-YRGSTINFG----------DYALQAT--EPCWITSRQIE AARRAMTRYI------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--DG-- VSEPIAREAMRLAAQKLPIKTKF-IRKESVQRRHRRIRKKV---NGTPNCPRLAVFRSNLHIYAQIIDD---V--GQHTI AAASTV-EPDL-KKSL----SSG-STCEASAAVGKLVAER--ALAQG-IEQVVFDRGGNLYH--GRVKALADAAREAGLQ F-------------------------------------------------------------TAE-VKAIARYIRMSPHK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAAAN----A- EHNE-GLDRATLVVSQAYADGGPSLRRYRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDTVQVISGR------DK-GKV GEVVKTDPTTS--TVV--VQGVNVRTKHVK----PQ--QE-GES-GQISTFEAPIHSSNVM-LYSTKE-------QV--A --SRVSYTF---TE--------EGKVR---MLKKTG---EII--MGQKIHPIGFRLG--IT-ADHKSCWYA------DSK R--YPETLQEDRQIRQYI--TKNLS-----NAGISDIRIERKA-D-QVDLAIHTARPGVVVGRGGSGIEQLRLGLQQDIR INVIEVQR---VDADAMLIAEYITQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYAYRTAQTIYGILGVKVWVFMAPNDTISDMLTRIRNACAVRHPTTQV-PTTKMTRSIAQVLKEEGFIEGFE ETG----E---G----VQKYLVLTLKYK--DKNR-------Q---PIINMLKRVSKPGLRVYSNCKDLPRVLGGIGIAIV STSKGIMTDREARRQNVGGEILCYIWTLQQKIRIRLKAFDRRLLDTSCEKIVDTANRTEATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVEIEVKLVKERVGVVVSNKMDKTVVVAIENRSPHPKYG KIVVKTKKFKAHDQE--NQCQEGDRVRIQETRPLSKTKRWVVAEIL-TS------------------------------- -MGRSL-KKGPFVSD-SLLTKIEKLNE---KGDKQ----VIKTWSRASTILPQMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KSR------R- >CYANO_Gloeobacter_violaceus_PCC_7421 Concatenation of 2 sequences MGIRKYRPMTPGTRQRSGADFAE-VTKS------------KP-EKKLTKYVHRKQGRNNQGVITSRF-RGGGHKRL---- YRFIDFK-R--DK-RGIPAEVLAIEYDPNRNARIALVQYT-DGEKRYILHPVGLKVGARISAGE-D-AP-IELGCALPLE KLPLGSNVHNIELLPGRGGQMARAAGAVAQLMAK--EGDYATLRLPSGEVRVVRKECYATLGQVGNLDAKNISIGKAGRQ -RWL-----GKR-P-HNRGVVMNAVDHPHGGGEGKS-P--IGGK-PQTP---WGKSALGTKTR-KRRKPSS-K-FIIRRR --------------------------------MSL---G-ILGRKLGMTQIFD-EEGR---------AIPVTVVEAGPCP VTQVK----SEA----T--DGY--TAVQLGF-------GT--ALTR----------PEVGHCK----------------- ---AGLEAPVRHLREFRL--------PDSSQY-----TP---GQ-QITV--D-L-FAAGQLVDVVGTSIGKGFAGGQKRH HFGR-GPMAHGS-KNHRA-PGSIGAG-TTPG-RVFPGKRMPGRMGNERVTVRKLTVVRVIPERN---------------- ----------VILIQGG-LPGVEGGLLMIS-MATCSIKD-WQGNAT-GEVDLDLPVA----SA-AT-ASHVVYLAFKRQM VNSRQGTASTLTRGE--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----LW---- RKGGVIFGPK-P-RDFEIKMNRKERRLALRTALQSRVED-------------------LIVVDEF--EGQLA-A------ --PKTRLLI--LRERQ--T---NTYLSARNLPNVK-V---------------ITAGNLNVRDLLATDW----IVVTGPAL ELIKVRMKDKYNREV----VPRLQEQFNYTNLMQVPKISKIVINRGLG-EASQNAKALDGSIAEVARIAGQKPVVTRAKK AIAGFKLRAGVPVGVTVTLRARRMYEFLDRLVSVALPRIRDFRGVSP-KAFDGRGNYTLGLREQLIFPEIE-----YDSV DKIRGMDITICTT-----------------------AKTDEEGRALLAALGMPFMSRIG-K--LPIAIPPKVEVT-L--- -D-G--R-RVVVKGPKGTLDLTL--PD-S--VEVVRED-GR--LLV---TR-R--GESRRAR-EQHGLGRTLVANMVTGV TTGFTKPMQIAGVGY--RVALTG-RK--LTIN--AGFSHPIEIEL-P-A-GIDIEVD----PINFVIKG-FDKQAVGDLA AKIRDIR------PPEPY---KGKGIRYTAEKILLKAGK----------MIQQQSRLSVADNTGARELLCIRVLG-GNRR Y--AFVGDIVVAVVKDAAPN-M-------GVKKSEVVRAVVVRTRQAIRRDNGMVIRFDDNAAVIID-KNGN-PRGTRVF GPVARELR-EKNFTKIISLAPEVLLR-L--EDAVPQSGS-RHRKLRVG-RGHSAGQ-GKTSGRGMRGQKCRSGGG-V--- -RPGF-E-GGQIPLYMRLPKLKG--FELVNLKQLVNIETLLDA-GILTLR---------VLG--DGE-A-H-V-A-LQI- TAAYFTASAREKIEAAGGTC-K---QQR--GRM---NGAA-CRGNEIEFG----------TYALQAL--EPVWMTSRQIE AARRAMTRYI------RRGGKIYIRVFPDKPVTQRAAETRMGSGK---------GAPEYWVCVVKP-GRILFEI--DG-- VAEEIAREAMRLAAAKLPIKSRF-IRKTATHRRHQRIRRKI---AGTPEQPRLAVYRSNRHIYAQVIDD---V--HQRTL VAASTL-EAPL-RSGE----EGT-ATCEAATAVGRLVAER--AKEKG-ITAVVFDRGGKLYH--GRVKAVADAAREAGLD F-------------------------------------------------------------ADE-VKAVARFIRMSPFK VRRILDQIRGRSYQDALIILQFM---------------------------------PHAATEPIKKVLESAAAN----A- EHNF-SLDRRALVVSTAFADGGPVLKRFRAGDRGRARPVRKRTSHITVAVRSKFHVKKGDTVQVISGK------DK-GKV GKVSEVLPTAG--KVI--VEGVNMQTKHVK----PQ--GD--QQ-GQTLRREAPIYSCKVM-LYSDKK-------KQ--A --SRVGHTV---TD--------AGKVR---VLKKTG---EIL--MGQKVHPIGLRLG--II-RDHRSRWFA------KAG E--YPALLAEDHKIRAYI--VKKLA-----SGGIADVDIERKA-D-QVEITIRTARPGVVVGRGGAGIDELKANLEKLIR INVVEVQR---VDAEAALIAEYIVGQLERRVAFRRAVRQAIQRAQRA-GVQGIKVMVAGRLNGAEIARSEWTREGRIPL- -HTLRADIDYAYKIAQTTYGTLGVKVWIFMAVNDTLADMLTRIRNASIVKHDIVPV-PSTRMTRSVAEVLKMEGLILEYQ DQG----E---G----KDRQLLLTLKYA--GRQR-------R---PLITNLKRVSRPGLRVYANRKELPRVLGGIGIAII STSQGVMTDRDARRAGVGGEVLCYVFLTQQKIRIRLQAFDHGLLDQSCSKIVDTANRTNAAAVGPIPLPTRIRRYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSAKTIDALMRLDLPAGVDIEVKLRKEKIGLVVSDAMQKTVVVAVENRVPHPKYK KIVVRTRKFKAHDEE--NRCKVGDRVRILESPPLSKTKRWVVLDILDEA------------------------------- -MGRSL-KKGVFVAD-HLLRKIETMNS---KNEKR----VIKTWSRASTIVPQMIGHTIAVHNGKEHLPVYVTE-QMVGQ KLGEFVPTRVFKGHA------G--KDK----KGK------R- >CYANO_Microcystis_aeruginosa_NIES-843 Concatenation of 2 sequences MGIRSFRPLTPGTRQAAISDFKE-ITKT------------EP-EKSLTHHKHSKQGRNNRGVVTSRH-RGGGHKRL---- YRIIDFR-R--DK-RDIPAKVAAIEYDPNRNARIALLFYK-DGEKRYIIAPAGLGVGDTVIAGE-N-AP-FEVGNALPLS RIPLGTEVHNIELVPGRGGQMVRAAGGFAQVVAK--EGDYVTIRLPSKEVRMIRRECYATIGKVGNAEARNISLGKAGRT -RHR-----GQR-P-HVRGSVMNPVDHPHGGGEGRA-P--IGRSGPMTP---WGKPALGRKTR-NKKKRSS-D-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDNKTGV---------AIPVTVVQAGPCP VTQVK----TKK----T--DGY--ESIQVGY-------KT--VLNK----------PLLGHLK----------------- ---AG-VSPLRHLIEYRL--------EDASAY-----TL---GQ-EITA--D-I-FQEGDLVDVAGTTIGRGFSGYQKRH NFKR-GNMTHGS-KNHRL-PGSTGAG-TTPG-RVFPGKRMAGQYGSTQVTIRKLSVVKIDSERN---------------- ----------LILIKGA-VPGKPGTLLNIT-MVNYTVKN-WQGEEA-GTGTLELKTA----KP-ET-AKHLIHRVVVSHL AAARQGNASSKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFEVKVNRKEKRLALRTALISQADN-------------------FIVVESF--AEQFS-Q------ --PKTKLLI--LTEIP--E---NVYLSGRNICNLK-I---------------IRADSLNVYDVILADR----VIATAAAL AKIEQKLKTTYQETI----VPKLKEQFGYTNIHQVPKVIKITVNRGLG-EASQNAKALESSKAELSTITGQQPVVTRAKK AIAGFKIREGMPVGVMVTLRGDRMYAFLDRLINLALPRIRDFRGISG-NSFDGRGNYSLGIREQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKNDEEGRALLKEMGMPFMSRIG-K--RPIPIPNKVTVD-I--- -D-G--A-TVTVKGPKGTLQRTL--PT-A--VAINKDG-ET--LLV---TR-Q--DDSRTAR-ERHGLCRTLVANMVEGV ATGFQKRLDIQGVGY--RAQAQG-SK--LVLN--VGYSKPVEMEM-P-D-GVSVAVE--N-STQVIVSG-IDKEAVGNTA AKIREVR------PPEPY---KGKGIRYLGEVVRRKVGK----------MIQQQTYLNVADNSGARKLMCLRVLT-GNCT Y--GGIGDKIIAVVKDAIPN-M-------PVKKSDVVTAVIVRTRQTVRRDSGMSIRFDDNAAVIIN-NDGN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVLMK-L--HEIAPQPGS-TKRRRRVG-RGVSAGQ-GASCGLGMRGQKSRSGTG-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLVNLRKLVTLESLLKA-KILTLK---------VLG--DGE-I-T-V-P-LKV- KAAAFSNSAKEKITAAQGTW-K---QQR--GRM---RGLA-TGGNTINFG----------DFALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTQRAAETRMGSGK---------GSPEFWVAVVKP-GFIMFEI--AG-- VAEPVAREAMRLAAQKLPIKTKF-IRKESVRRRHQRVRRKI---NGTAERPRLSVFRSNNHIYAQIIDD---V--AQHTL AAASTL-EATL-RGEL----EST-ATQEASAAVGKLVAQR--ALDKG-IEQVVFDRGGNLYH--GRVKALAEAARSAGLN F-------------------------------------------------------------SNE-VKAIARYIRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACDPILKVLRSAVAN----A- EHNE-GLDPATLVVSQAFADGGPTLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDVVQVIAGS------DK-GKV GEILRALPQES--TVV--VKGVNIRTKHTK----PQ--QE-GES-GQIVTYEAPIHSSKVM-LYSEKK-------KI--A --SRVGYTL---TE--------DGKVR---ILKKTG---EII--MGQKIHPLGFRLG--VI-KDHKSCWYA------DAK R--YPELLQEDRRIRQYV--EKNLA-----NAGIADIRIERKA-D-QVDISIHTARPGVVVGRGGTGIEQLRLGLQKAIR INVIEVAR---VDADANLIAEYIAQQLERRVSFRRVVRQAIQRAQRA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTASTIYGILGVKVWIFMSANDTISDMLTRIRNACAVRQTTTQI-PTTRMTRSIAQVLKDEGFIADFE EVG----E---G----IKSQLVLSLKYK--GKNR-------Q---PIITTLTRVSKPGLRVYSNSKDLPRVLGGIGIAIV STSKGIMTDREARKQNVGGEVLCYIWLQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIENRSPHPKYG KIVVKTQKFKAHDAE--NQAKQGDRVRIRETRPLSKTKRWEVAEILTDS------------------------------- -MGRSL-KKGPFVAG-HLMEKIEKLNA---QGSKQ----VIKTWSRASTIIPDMVGHTIAVHNGKQHVPVYVSE-QMVGH KLGEFAPTRTFRGHA------K--SDK----KAG------RK >CYANO_Nostoc_punctiforme_PCC_73102 Concatenation of 2 sequences MGTRSYRPYTPSTRQVTVSDFAE-ITKT------------EP-EKSLTTSKHRAKGRNNTGRITSRR-RGGGHKQL---- YRIIDFK-R--DK-HNIPAKVAAIEYDPNRNARIALLYYQ-DGEKRYILHPNGLKVGTIIISGP-E-SP-FEDGNALPLS RIPLGTSVHNVEMTPGKGGQIVRAAGASAQVVAK--EGDYVTLKLPSGEVRLIRRDCYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGAKTR-NRKKLSS-K-FIVRRR --------------------------------MSV---G-ILGTKLGMTQIFD-EAGV---------AIPVTVIQAGPCT VTQVK----TKQ----T--DGY--FAIQVGF-------GE--VLNR----------PLLGHLK----------------- ---SS-APALRHLNEYHT--------DSSSDY-----AL---GQ-QIKA--D-I-FSEGQIVDVVGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHRA-PGSIGAG-TTPG-RVYPGKRMAGRLGGKRITIRKLTIVRVDAERN---------------- ----------LLLIKGA-IPGKPGALVSVV-MVESVVKN-WQGEQV-GETTFELRVA----KE-ET-ASHIVHRALVRQL TNARQGNASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFDLKLNRKERRLALRTAFVGRIDD-------------------LIVVEEF--STELS-R------ --PKTKLLI--LSEIADTD---NVYLSARNIENLK-L---------------IAANQLNVFDLLHADK----IVVTASAL EKIQTRLKSLYQETI----VPKLINQFQYTNVHQVPKLVKVTINRGLG-EAAQNAKSLEASINEIALVTGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRAERMYAFFDRLVSLSLPRIRDFRGVSP-KSFDGRGNYTLGVREQLIFPEVE-----YDSV DQVRGMDISIITT-----------------------AKNDEEGRALLKELGMPFMSRIG-K--RPITIPAKVQVA-I--- -N-G--T-NIVVKGPKGELSRTL--RD-N--VSLSQEG-EI--LHV---NR-R--DETRTSK-QLHGLSRTLVANMVEGV SQGFQRRLEIQGVGY--RAQLQG-RN--LVLN--MGYSHQVQIEP-P-D-GIQFAVE--G-TTNVIVSG-YDKEIVGNTA AKIRAVR------PPEPY---KGKGIRYAGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLG-GNRR Y--GFIGDKIIAVVKDATPN-M-------AVKKSDVVEAVIVRTRKAVSRDSGMSIRFDDNAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--HDVKPQKGS-KKRKKRVA-RGISAGQ-GASAGLGMRGQKSRSGSG-T--- -RPGF-E-GGQQPLYRRLPKLKG--FPIINVEKLVTLASLKAA-GILTLK---------ILG--NGE-L-S-T-P-LKV- QAAAFTGTARSKIEAAGGSC-K---QQR--GRM---EGLA-TRGSTLNFG----------DFALQAQ--EPAWITSRQIE ASRRAMTRYI------RRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEI--GG-- VSEEIAREAMRLASFKLPIKTKF-IRRESKNRRHRRVRGKV---VGSPERPRLAVFRSNEHIYAQVIDD---S--QHQTI VAASTL-EPEL-KSSL----ASG-ANRDASVQVGKLIAVR--SLEKG-ITKVVFDRGGNLYH--GRVKALADAAREAGLD F-------------------------------------------------------------TTE-VKAIARFIRISAYK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRATEPILKVLRSAAAN----A- EHNA-GLDRTQLVITQAYADQGPPLKRFQPRAQGRAYQIRKPTCHITVAVGAKMHVKTGDTVQVIAGK------DK-GKI GEIVQALPQLS--KVI--VKGVNIKTKHVK----PQ--QE-GES-GRIVTQEFPIHSSNVM-LYSTKQ-------NV--A --SRVCYTF---TS--------EGKVR---KLKKTG---EIL--MGQKIHPVGFRLG--IT-HEHQSRWFA--------V PDRYPELLQEDYKLRQYI--EQKLGRLAQNNAGISEVRIERKA-D-QIDLEVRTARPGVVVGRGGQGIESLRTGLQGLIR INVVEVQR---VDADAYLIAEYIAQQLERRVSFRRVVRQSIQRAQRA-GVQGIKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAKTVYGILGIKVWVFMAANDTIADMLTRIRNANLARHQTTQV-PATKMTRSIAKVLREEGFIAEIE EAE----E---G----VKHNLVISLKYK--GKNR-------Q---PLITALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGIMTDREARRQNLGGEVLCYVWLQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKLVKERVGLVVSDKMQKTVVVAIENRAPHPKYG KIVVNTQRYKVHDEE--NKCKVGDRVRIQETRPLSKTKRWKITEVLNIK------------------------------- -MGRSL-KKGPFVAD-HLLKKIEKLND---NNRKE----VIKTWSRASTILPLMVGHTIAVHNGRQHVPVFVNE-QMVGH KLGEFAPTRTYRGHG------K--SDK----KAG------R- >CYANO_Nostoc_sp_PCC_7120 Concatenation of 2 sequences MGTRSYRPYTPSTRQVTISDFAE-ITKT------------EP-EKSLTVYKHRAKGRNNQGRITSRR-RGGGHKRL---- YRIIDFK-R--DK-RSIPATVIAIEYDPNRNARIALVSYE-DGEKRYILHPNNLKVGTVIIAGP-E-SP-IEDGNALPLA NIPLGTSVHNVELKAGKGGQIVRSAGATAQVVAK--EGNYVTLKLPSGEVRLIRRECYATIGQVGNTDARNLSAGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPTLGAKTR-KPKKASS-K-LIIRRR --------------------------------MSV---G-ILGTKLGMTQIFD-EAGV---------AIPVTVVQVGPCV VTQVK----SKQ----T--DGY--AAIQVGY-------GE--VLNR----------PLLGHLK----------------- ---SS-APALRHLKEYHT--------DGSSDY-----AL---GQ-EIKA--D-I-FSVGELVDVIGTSIGRGFAGNQKRN NFGR-GPMSHGS-KNHRA-PGSIGAG-TTPG-RVYPGKRMAGRLGGTRVTIRKLTVIRVDAERN---------------- ----------LLLIKGA-VPGKPGALLSIV-MVESVVKN-WQGEQI-GQKTFELRVA----KE-TT-AAHIVHRALVRQQ TNARQGTASTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDFDLKMNRKERRLALRTAFVSRIDD-------------------LILVEEF--SNELS-R------ --PKTKLLI--LSEFP--E---NVYLSARNIENLK-L---------------IAADQLNVYDLLHADK----IVVTTSAL EKIQTRLKTLYQETI----VPKLTQQFQYTNVHQVPKLVKITVNRGLG-EAAQNAKSLEASLTEIATITGQKPVVTRAKK AIAGFKIRQGMPVGIMVTLRGERMYAFFDRLISLSLPRIRDFRGISP-KSFDGRGNYTLGVREQLIFPEIE-----YDSI DQIRGLDISIITT-----------------------AKNDEEGRALLKEFGMPFMSRIG-K--RPITVPAKVQVT-I--- -D-G--T-KVVVKGPKGELSREL--PA-N--VSVSQEG-ET--LQV---TR-R--DETRTSR-QLHGLSRTLVANMVEGV SQGFQRRLEIQGVGY--RAQVQG-RN--LVLN--MGYSHQVQIEP-P-D-GIQFVVE--N-NTNVIVSG-YDKEIVGNTA AKVRAVR------PPEPY---KGKGIRYAGEVVRRKAGK----------MIQPQTYLNVADNSGARKLMCIRVLA-GNSR Y--GFIGDKIIAVVKDATPN-M-------AVKKSDVVEAVIVRTRHHIRRDSGMTIRFDDNAAVIIN-KDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--NDVKPQKGS-KKRRRRVG-RGISAGQ-GASAGLGMRGQKSRSGSG-T--- -RPGF-E-GGQQPLYRRIPKLKG--FPVINVEKLVTLESLRAA-GILTLK---------ILG--NGD-L-G-V-A-LNV- KAAAFTGQARSKIEAAGGSC-K---QQR--GRM---GGLA-HRGSTLNFG----------DFALQAQ--EPAWITSRQIE ASRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEI--AG-- VTEEIAREAMRLAAYKLPIKTKF-IRRESKERRHRRVRGKV---QGSPERPRLAVFRSNEHIYAQVIDD---T--QHHTL AAASTV-EPEL-KSSL----ASG-SNCEASAQIGKLIAAR--SLEKG-ITKVVFDRGGNLYH--GRIKALAEAAREAGLD F-------------------------------------------------------------TTE-VKAIARFIRMSPYK VRRVLDQIRGLSYREALIILEFM---------------------------------PYRATEPVLTLLRSAAAN----A- EHNA-GLDRAELVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITLAVAA---------MQIIAGK------DK-GKV GEVIKALPQLS--KVV--VKGVNIKTKHVK----PQ--QE-GES-GRIVTQEAPIHSSNVM-LYSTKQ-------NV--A --SRVCYTF---TA--------EGKVR---KLKKTG---EIL--MGQKIHPVGFRLG--IT-QEHQSRWFA------ESR ---YPELLQEDHKLRQYI--EQKLGRLAQNNAGISEVRIERKA-D-QIDLEVRTARPGVVVGRGGQGIEALRTGLQTLIR INVVEVQR---VDADAYLIAEFIAQQLERRVSFRRVVRQAIQRAQKA-GIQGIKVQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYSYCTAKTVYGILGIKVWVFMAANDTIADMLTRIRNANMARHQTTLV-PATKMTRSIAKVLQEEGFIAEIS EEG----D---E----VKRNLVIALKYK--GKNR-------Q---PLITALKRVSKPGLRVYSNRKELPRVLGGIGIAII STSSGIMTDREARRQNVGGEVLCYVWLQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKLIKERVGLVVSDKMQKTVVVAIENRAPHPKYG KIVVKTRRYKAHDED--NKCKVGDRVRIQETRPLSKTKRWQVAEILNTK------------------------------- -MGRSL-KKGPFIAD-HLLSKIEKLND---RNEKQ----VIKTWSRASTILPLMVGHTIAVHNGRQHVPVFISE-QMVGH KLGEFAPTRTYRGHG------K--SDK----KAG------R- >CYANO_Prochlorococcus_marinus_AS9601 Concatenation of 2 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITSA------------KP-ERSLIVSKHRVKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-RNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGVKVGQNVISGE-S-VP-IEDGNAMPLS VMPLGSSVHCVELYAGRGAQMVRSAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKPALGLKTR-KKNKPSN-K-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-DKGN---------SVPVTLIEAGPCR VTQLK----TTA----L--DGY--TAVQIGY-------GL--SLSK----------PEKGHLK----------------- ---SG-EELLKHLKEYRV--------EETSSY-----EI---GK-QITV--K-N-FEVGQKVDISGKSMGRGFAGYQKRH GFSR-GPMSHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGRYGGKQITTKGLLVLKIDDQKN---------------- ----------LLVVKGS-VPGKPGSIINIK-MTTLETLK-WDGKKS-GKVSLDLAVA----KE-TS-SADLIHRAVLRQL ANKRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RSYNLDMNRKERRLALRTALMSRVSD-------------------MKAVEDF--GSTLK-Q------ --PKTSLVI--LDSPS--D---IIKKSINNIEKVK-L---------------IAADQLNVFDILNANK----LVIGQSAI DKIQMTLKNRYKESI----RPKLLKDLGLKNIHQVPKVVKVNVNRGLG-EAASNSKALEASLNEMATITGQKALVTRAKK AIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTVGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------AKSDQEGKALLQELGMPFMSRIG-K--TPVLIPEKVTVD-F--- -D-G--L-TVTVKGPKGELKRLM--PE-G--VSFDKKD-NT--VVV----S-P-TTTKIHSR-QRHGLCRALIANMVEGV TQGFSKKLEIVGVGS--RAQVKG-KN--LVVS--AGYSHPVEMIP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYHDERILRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVATVKDALPNMG--------VKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVIST-L--NTLKSNSGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FEIINLEKLVNIDSLVKK-GLIFLK---------ILG--NGK-I-N-V-K-LKV- QAHSFTKVAKQKIEDAGGSC-K---QHR--GRM---RGVA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYI------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGED ITEETAKEAMRLAQYKLPVKTKF-IRKLQTQKRHRRLRRYL---IGDATRPRLSVYRSNNHIYAQVIDD---S--AQTTI CSASTV-DKEL-KEKS----EKLPSDCNSSSIVGKLLAKR--AIKKG-IKQVIFDRGGNLYH--GRVKALADAAREAGLE F-------------------------------------------------------------TKK-AIAHGNYVRGSASK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNL-GMDPSTLVISSAWANSGPVMKRYRPRAQGRAFSIKKQTCHISISVESKMRIKTGDLVKVINGK------DK-GKT GEVLKTIPLEN--RVV--VKGINLRTKHVK----PT--QE-GET-GRILTEEASLHASNVM-FFSKDK-------NL--T --SKIEYFI---DK--------EGKKR---RLKKTG---EVI--MGHKIHPSGLRLG--IT-QEHRSKWFA------TSK T--YPILLQEDFKIRTFI--QKKYG-----AAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMALQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTTTTI-PGSKMSLSIAKVLQKEGFISDIN EEG----E---G----YKSQIILGLKYS---GKN-------K--FPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGIGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIQTADTTSASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSRTTRYKAHDPE--NTCVLGDRVKIRETRPLSAHKRWAIEEILNKT------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNT---DNDKS----VIKTWSRSSTILPLMIGHTIAVHNGKTHIPVFITE-QMIGH KLGEFAPTRTYRGHI------R---DK----KGA------KS >CYANO_Prochlorococcus_marinus_marinus_CCMP1375 Concatenation of 2 sequences MAIRTFRPYTPGTRTRVVTDFNE-VTGR------------KP-ERSLVIAKHRLKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--NK-HGVPAKVAAIHYDPHRNARLALLFYK-DGEKRYILAPAGISIGQEVLSGK-D-VP-IEIGNALPLS SIPLGSSVHCVELYPGRGGQMVRCAGSSAQLMAK--EGEYVALKLPSTEVRLVRGECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--VGRAGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-EKGR---------SIPVTLVEAGPCR ITQLK----SSA----T--DGY--SAVQIAF-------GA--VINK----------PFQGHLK----------------- ---SG-DDLLRYMSEYRV--------KDVGEF-----QL---GA-QITV-GD---FEEGQKVDVSGTSMGRGFSGYQKRH GFSR-GPMSHGS-KNHRE-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKITTRGLMIMKVDSDKN---------------- ----------LLVIKGS-LPGKPGSLLNIR-MANCAVLD-WQGKEA-GKASLNLKVA----KD-SS-AVDLMHRAVLRQQ AHSRQGTASTLTRAE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RQYNLSMNRKERRLALRTALMARFND-------------------VIAVKDF--GSKLK-V------ --PKTKLII--LSQPS--D---IIRRSVRNLEKVK-L---------------IAAEHLNVFDLLNANS----LIIGEDAL GKIKMSLKNRYRETI----RPKLLKDLGFSNLHQVPKVVKINVNRGLG-EAAQNSKALEASLSEVSTITGQKALVTRAKK AIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNFTLGVKEQLIFPEIS-----FDKI DAIRGMDITIVTS-----------------------ARTDEEGRALLKEMGMPFMSRIG-K--KPIPVPEKVAVT-L--- -D-G--L-LVTVKGPKGELTRTL--PE-G--VTIDQTD-GL--IIV------SADSEKRKSR-ERHGLSRTLVANMIEGV NNGYSKQLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEVIP-P-E-GITFKVE--N-NTNVLVSG-IDKELVGNEA AKIRAIR------PPEPY---KGKGIKYLGERILRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVAAVKDAVPNMG--------VKKSDVVKAVVVRTKATLRRETGNSIRFDDNAAVLIN-EDKN-PRGTRVF GPVARELR-ERNYTKIVSLAPEVIIS-L--DSLKPNKGA-RKRKTRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLINVASLVNLDSLVKT-GIVTLK---------VLG--NGN-L-K-V-K-LVV- QAAAFTASAKTKIEGAGGSC-K---QQR--GRM---RGVA-TRGNKIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGEE ITEEIAKEAMRLAQYKLPIKTKF-LRKQKTQKRHKRLRRNL---SGTDQRPRLAVFRSNNHIYAQVIDD---V--AQNTL CAASTL-EKEFLSNSK----VNA-STCAASTAVGEMLAKR--ALGKG-IKQVVFDRGGSLYH--GRVKALAEAARQAGLT F-------------------------------------------------------------LPL-AQAHGRFIRGSASK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- ENNL-GMDPSSLIIKTASADMGPSMKRYRPRAQGRAFAIKKQTCHISIAVAPKMRIRKGDTVQVINGK------EK-GKT GEVLKTLPIEN--RVI--VQGINLRTRHVK----PT--QE-GES-GRIVTEEASLHASNVM-VYSTKQ-------KT--A --SRVEVFI---DK--------DGKKR---RLKKTG---ELI--MGHKIHPNGLRLG--IT-QEHRSRWYA------SSK T--YPLLLQEDDRIRVFI--QKKYG-----AAGISDVLIARKA-D-QLEVELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEIER---VDADAHLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRAEIDYANKTANTTYGVLGIKVWVFMANHDPISDMLTRIRNASQKRHENTRI-PASRMSRSIAKVLQNEGFISQVS EEG----E---G----VKTQLVLELKYS--GKHR-------H---PTIRSMKRVSKPGLRIYKNNRGLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERLGTVVSDKMDKTVVVAVVNRFPHSIYQ KTVSRTTRYKAHDEE--NNCKVGDRVRITETRPLSATKRWSVAEVLRTT------------------------------- -MGRSL-KKGPFIAD-SLIKKVEKQNS---DDDKS----VIKTWSRASTILPMMIGHTIAVHNGKTHVPVFITE-QMVGH KLGEFAPTRTYRGHM------K---DK----KGG------R- >CYANO_Prochlorococcus_marinus_MIT_9211 Concatenation of 2 sequences MAIRTFRPYTPGTRTRVVTDFNE-LTGR------------KP-ERSLVVSKHRLKGRNNRGVITCRH-RGGGHKRL---- YRIVDFR-R--NK-HDVPAKVAAIHYDPHRNARLALLFYS-DGEKRYILAPAGIAIGQEVISGP-K-VP-IETGNAMPLS AIPLGSSVHCVELYAGRGGQMVRSAGASAQVMAK--EGDYVALRLPSTEVRLIRRECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--VGRAGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-DKGR---------SVPVTLIEAGPCR ITQLK----SLA----T--DGY--SAVQIGY-------GF--TVNK----------PFKGHLK----------------- ---SG-EGFLRHLHEYRV--------DDLGVY-----EL---GA-KITV--G-N-FEAGQKVDVSGNSMGRGFAGYQKRH SFSR-GPMSHGS-KNHRQ-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKITTRGLTIMKIDSDRN---------------- ----------LLVVKGS-VPGKPGSLLNIR-MANCVVLD-WQGQEA-GKATLDLKVA----KE-TT-AVDLIHRAVVRQQ AHSRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RSFSLGMNRKERRLALRTALMARIND-------------------LMIVQDF--GTALK-V------ --PKTRLII--LAQPS--E---IIIRSVRNIERVK-V---------------IGADQLNVFDLLNANS----LVIGEKAL STIKMSLKHRYRETI----RPKLLKDLGLSNIHQVPKVVKVNVNRGLG-EAAQNSKTLEASLSEMATITGQKALVTRAKK AIAGFKIREGMPIGCTVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVKEQLIFPEIS-----FDKI DTIRGMDITIVTS-----------------------ARSDEEGRALLKALGFPFMSRIG-K--QPIPVPEKVAVE-L--- -D-G--L-SLTVKGPKGELSRTL--PE-G--VSISQVD-NS--IVV------SAINSKRKSR-ERHGLSRSLVANMVEGV SKGYSKKLEIVGVGS--RAQVKG-KN--LIVS--AGYSHPVEVIP-P-D-GITFVVE--N-NTNVTVSG-IDKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERIIRKAGK----------MIQQETFLTVADNSGAKKLQCIRVLG-SNRR Y--AHVGDVIVAAVKDALPNMG--------VKKSDVVKAVVVRTKATLRRETGNSIRFDDNAAVLIN-EDKN-PRGTRVF GPVARELR-ERNFTKIVSLAPEVIIK-L--DSLKPNKGS-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLVNVASLVNLDVLVKE-GILTLK---------VLG--NGN-L-K-V-K-LNV- QAAAFTMSAKSKIEGAGGTC-K---QQR--GRM---RGVA-TRGNKIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGEE ITESIAREAMRLAQYKLPIKTKF-IKKQQTQKRHKRLRRHL---NGTNHRPRLAVFRSNNHIYAQVIDD---E--AQSTI CSASTL-DKDL-REKL----KASGGSCDASMAVGALLAQR--ALAKG-IEQVVFDRGGNLYH--GRVKALAKSAREAGLK F-------------------------------------------------------------KTKFAQAHGRYIRGSASK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- ENNM-GLDPASLVITRATADMAPSMKRYRPRAQGRAFAIKKQTCHISISVAP-MRIRKGDTVQVINGK------EK-GKT GEVLKTLPFEN--RVV--VQGINLRTRHVK----PT--QE-GET-GRIVTEEASVHASNVM-IYSTEK-------KV--A --SKVEIFI---EK--------DGKKR---RLKKTG---ELI--MGHKIHPNGLRLG--IT-QEHRSRWYA------SSK T--YPTLLQEDDRIRGFI--QKKYA-----SAGISDVLIARKA-D-QLEVELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEIER---VDADAHLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRAEIDYANKTANTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTRI-PASRMSRSIAKVLQKEGFIAQIS EEG----E---G----FKTQLVLELKYS--GKHR-------H---PTIRSMQRVSKPGLRIYKNTRGLPKILGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYNPSAKTIDALMKLDLPSGVDIEVKLLKERLGTVVSDKMDKTVVVAVENRFPHPIYQ KIVSRTARYKVHDAE--NTCKVGDKVRITETRPLSASKRWTVAEVLRST------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNS---NDDRS----VIKTWSRASTILPVMIGHTIAVHNGKSHIPVFITE-QMVGH KLGEFAPTRTYKGHI------K---DK----KGA------R- >CYANO_Prochlorococcus_marinus_MIT_9215 Concatenation of 2 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITSA------------KP-ERSLIVPKHRVKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-RNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGVKVGQNVISGE-S-VP-IEDGNAMPLS VMPLGSSVHCVELYAGRGAQMVRSAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKPALGLKTR-KKNKPSN-K-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-DKGN---------AVPVTLIEAGPCR VTQLK----TNA----L--DGY--TAIQIGY-------GV--SISK----------PEKGHLK----------------- ---SG-EELLKHLKEYRV--------EETSSY-----EI---GN-QITV--K-N-FEVGQKVDISGKSMGRGFSGYQKRH GFSR-GPMSHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGRYGGKQITTKGLLVLKIDDQKN---------------- ----------LLVVKGS-VPGKPGSIVNIK-MTTLETLK-WDGKKS-GKVTLDLTVA----KE-TS-SADLIHRAVLRQL ANKRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RSYNLDMNRKERRLALRTALMSRVSD-------------------MKAVEDF--GSTLK-Q------ --PKTSLVI--LDSPS--D---VIKKSINNIEKVK-L---------------IAADQLNVFDILNANK----LLIGQSAI DKIQMTLKNRYKESI----RPKLLKELGLKNIHQVPKVVKVNVNRGLG-EAASNSKALEASLNEMATITGQKALVTRAKK AIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTVGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------ARSDQEGKALLQELGMPFMSRIG-K--TPVLIPDKVTVD-F--- -D-G--L-IVTVKGPKGELKRQM--PE-G--VCFDKKD-NT--VVV----S-P-TTSKIFSR-QRHGLCRALIANMVEGV SQGFSKKLEIVGVGS--RAQVKG-KN--LVVS--AGYSHPIEMIP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYHDEIILRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVATVKDALPNMG--------VKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVIST-L--NTLKSNSGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FEIINLEKLVNIDSLVKK-GLIFLK---------ILG--NGK-I-N-V-K-LKV- QAHAFTKVAKQKIEAAGGSC-K---QHR--GRM---RGVA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYI------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGED ITEEVAKEAMRLAQYKLPVKTKF-IRKLQTQKRHRRLRRFL---IGDATRPRLSVFRSNNHIYAQVIDD---S--AQTTI CSASTV-DKEL-REKS----EKLPSDCNSSSIVGKLLAKR--AIKKG-VKQVIFDRGGNIYH--GRVKALADAAREAGLE F-------------------------------------------------------------TKI-AIAHGNYIRGSASK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNL-GMDPSTLIISSAWANSGPVMKRYRPRAQGRAFSIKKQTCHISISVESKMRIKTGDLVKVINGK------EK-GKT GEVLKTIPLEN--KVV--VKGINLRTKHVK----PT--QE-GET-GRILTEEASLHASNVM-FFSKEK-------NL--T --SKIEYFI---DK--------EGKKR---RLKKTG---EVI--MGHKIHPSGLRLG--IT-QEHRSKWFA------TSK T--YPILLQEDFKIRTFI--EKKYG-----AAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMALQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTTTTI-PGSKMSLSIAKVLQKEGFISEIN EEG----E---G----YKSQIILGLKYS---GKN-------K--FPTIRSMQRVSKPGLRIYKNTRALPKVLGGLGVAII STSKGVMSDRDARKQGIGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIQTADTTSASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSRTTRYKAHDPE--NTCVTGDRVKIRETRPLSAQKRWAIEEILNKT------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNT---DNDKS----VIKTWSRSSTILPVMIGHTIAVHNGKTHIPVFITE-QMIGH KLGEFAPTRTYRGHI------R---DK----KGA------KS >CYANO_Prochlorococcus_marinus_MIT_9301 Concatenation of 2 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITSS------------KP-ERSLIVSKHRVKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-RNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGVKVGQNVISGE-S-VP-IEDGNAMPLS VMPLGSSVHCVELYAGRGAQMVRSAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKPALGLKTR-KKNKPSN-K-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-EKGN---------SVPVTLIEAGPCR ITQLK----TTA----L--DGY--TAVQIGY-------GL--SISK----------PEKGHLK----------------- ---SG-EELLKHLKEYRV--------EETSSY-----EI---GN-QITV--K-N-FEVGQKVDISGKSMGRGFAGYQKRH GFSR-GPMSHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGRYGGKQITTKGLLVLKIDDQKN---------------- ----------LLVVKGS-VPGKPGSIINIK-MTTLETLK-WDGKKS-GKVSLDLAVA----KK-TS-SADLIHRAVLRQL ANKRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RSYNLDMNRKERRLALRTALMSRVSD-------------------IKAVEDF--GSTLK-Q------ --PKTSLVI--LDSPS--D---IIKKSINNIEKVK-L---------------IAADQLNVFDILNANK----LVIGQSAI DKIQMTLKNRYKESI----RPKLLKDLGLKNIHQVPKVVKVNVNRGLG-EAASNSKALEASLNEMATITGQKALVTRAKK AIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTVGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------ARSDQEGKALLQELGMPFMSRIG-K--TPVLIPDKVSVD-F--- -D-G--L-TVTVKGPKGELKRQM---P-E-GVSFDKKD-NT--VIV----S-P-TTTKIFSR-QRHGLCRALIANMVKGV SQGFSKKLEIVGVGS--RAQVKG-KN--LVVS--AGYSHPIEMIP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYHDERILRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVATVKDALPNMG--------VKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVIST-L--NTLKSNSGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FEIINLEKLVNLDSLVKK-GLIFLK---------ILG--NGK-L-N-V-K-LKV- QAHAFTKVAKQKIEDAGGSC-K---QHR--GRM---RGVA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYI------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGED ITEETAKEAMRLAQYKLPVKTKF-IRKLQTQKRHRRLRRFL---IGDATRPRLSVFRSNNHIYAQVIDD---S--AQTTI CSASTV-DKEL-REKS----EKLPSDCNSSSIVGKLLAKR--AIKKG-IKQVIFDRGGNLYH--GRVKALADAAREAGLE F-------------------------------------------------------------QKT-AVAHGNYVRGSASK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNL-GMDPSTLVISSAWANSGPVMKRYRPRAQGRAFSIKKQTCHISISVESKMRIKTGDLVKVINGK------EK-GKT GEVLKTIPLEN--RVV--VKGINLRTKHVK----PT--QE-GET-GRILTEEASLHASNVM-FFSKEK-------NL--T --SKIEYFI---DK--------EGKKR---RLKKTG---EVI--MGHKIHPSGLRLG--IT-QEHRSKWFA------TSK T--YPILLQEDFKIRTFI--QKKYG-----AAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMALQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTTTSI-PSSKMSLSIAKVLQKEGFISDIN EEG----E---G----YKSQIILGLKYS---GKN-------K--FPTIRSMQRVSKPGLRIYKNTRALPKVLGGLGVAII STSKGVMSDRDARKQGIGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIQTADTTSASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSRTTRYKAHDPE--NTCVLGDRVKIRETRPLSAHKRWAIEEILNKT------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNT---DNDKS----VIKTWSRSSTILPLMIGHTIAVHNGKTHIPVFITE-QMIGH KLGEFAPTRTYRGHI------R---DK----KGA------KS >CYANO_Prochlorococcus_marinus_MIT_9303 Concatenation of 2 sequences MAIRTFRPYTPGTRTRVVTDFNE-VTGR------------KP-ERSLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRIVDFR-R--NK-HGIPAKVAAIHYDPHRNAHLALLFYT-DGEKRYILAPNGIAIGQQLISGP-E-SP-IETGNALPLS AIPLGSSVHNVELYAGRGGQMARTAGSSAQVMAK--EGDYVALKLPSTEVRLVRHECYATLGEVGNSEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-DQGR---------AIPVTLIEAGPCR ITQLK----TSD----I--DGY--AAVQIGF-------GD--TINK----------PSKGHLK----------------- ---SG-EVLLKHLREYRV--------EGLEGL-----EL---GA-AITV--G-S-FEAGQKVDVSGDTMGRGFSGYQKRH GFSR-GPMSHGS-KNHRE-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKRTTRGLTILKVDSNRN---------------- ----------LLVVKGS-VPGKPGALLNIR-MAECVVHD-WQGKEA-GKASLELKVS----KE-TT-AVDLMHRAVLRQQ AHSRQGTASTLTRAE--------VR-GGGRKPY---------KQKGTGRAR--------QGT---IR-TP----LR---- PGGGIIFGPK-P-RTYNLAMNRKERRLALRTALMARLED-------------------VIVVKDF--GDSLK-A------ --PKTRLII--LSTPS--E---IIRRSVRNLEKVK-L---------------IAADQLNVFDLLHANS----LVLSEEAL AKIQMSLKQRYRETI----QPKLLKDLSLSNIHEVPKVLKITVNRGLG-EAAQNAKSLEASITELATITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQLIFPEVS-----FDKI DAIRGMDITIVTS-----------------------ARTDEEGQSLLREMGMPFMSRIG-K--NPIPIPDKVAVT-L--- -D-G--L-AVSVKGPKGELNRTL--PE-G--VSVSQVE-NT--IVV----T-P-TSQKRKSR-ERHGLCRSLVANMVEGV SKGYTRKLELIGVGS--RAQVKG-KK--LVVS--AGFSHPVEMDP-P-E-GITFAVE--N-NTNVTVSG-ADKELVGNEA AKIRAIR------PPEPY---KGKGIRYEGERILRKAGK----------MIQQESFLTVADNSGAKRIQCIRVLG-SNRR Y--AHVGDIIVAAVKDAMPN-M-------SVKKSEVVKAVVVRTKATLRRETGNSIRFDDNAAVLIN-EDKN-PRGTRVF GPVARELR-ERNFTKIVSLAPEVILR-L--DSLKANAGA-RRRKMRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FTTVNVAALINLDTLVKN-GVVTLK---------VLG--NGE-L-K-V-K-LTI- QAAAFTATARNKIEAAGGTC-K---QQR--GRM---RGVA-TRGNTIAFG----------EFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGEE ITEEIAREAMRLAQYKLPIKTKF-IRKQQTQKRHRRLRRHL---NGTAQRPRLAVFRSNNHIYAQVIDD---E--AQNTL CAASTL-DKDLRTSLK----ADG-SSCDASNAVGDLVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKSLADAAREAGLQ F-------------------------------------------------------------TTTIAKAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPASLVIAQASADMGPSMKRYRPRAQGRAFAIKKQTCHISIAVAAKMRIHKGDTVQVITGK------DK-GKT GEVLRTLPIEN--RVI--VQGVNIRTRHVK----PT--QE-GES-GRIVTEEASVHASNVM-LYSNNK-------KI--A --SRVALVV---EK--------DGKKR---RLKKTG---ELI--MGNKIHPTGLRLG--IT-QEHRSRWYA------TSK M--YPILLQEDDRIRRFI--HKKYG-----AAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRTGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARNEWTREGRVPL- -HTLRAEIDYATKVASTTYGVLGIKVWIFMANHDPISDMLTRIRNASEKRHQTTRV-PASRMSRSIAKVLQQEGFISEIS EEG----E---G----VLTHLVLELKYS--GKHR-------H---PTIRSMQRVSKPGLRIYKNTRALPKVLGGLGMAII STSKGVMSDRDARKQGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLCS PHVDKDSR-EHFETRTHRRIIDIYNPSAKTIDALMKLDLPSGVDIEVKLLKERLGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDAG--NTCRIGDRVRITETRPISRSKRWTVAEVLSHS------------------------------- -MGRSL-KKGPFIAD-SLLRKLEKQNA---DDDKS----VIKTWSRASTILPMMIGHTIAVHNGRSHVPVFITE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Prochlorococcus_marinus_MIT_9312 Concatenation of 2 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITSA------------KP-ERSLIVSKHRVKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-RNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGVKVGQNVISGE-S-VP-IEDGNAMPLS VMPLGSSVHCVELYAGRGAQMVRSAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKPALGLKTR-KKNKPSN-K-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-DKGN---------AVPVTLIEAGPCR VTQLK----TTT----L--DGY--SAVQIGY-------GL--SINK----------PEKGHLK----------------- ---SG-EELLKHLKEYRV--------EETTSY-----EI---GN-QITV--K-N-FEVGQKVDISGKSMGRGFAGYQKRH GFSR-GPMSHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGRYGGKQITTKGLLVLKIDDQKN---------------- ----------LLVIKGS-VPGKPGSIVNIK-MTTIETLK-WDGKKS-GEVKLDLTVA----KE-TS-SADLIHRAVLRQL ANKRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RSYNLDMNRKERRLALRTALMSRISD-------------------VKAVEDF--GSTLK-Q------ --PKTSLVI--LDSPS--E---VIKKSINNIEKVK-L---------------IAADQLNVFDILNANK----LVIGQSAI NKIKMTLKNRYKESI----RPKLLKDLGLKNIHQVPKVVKVNVNRGLG-EAASNSKSLEASLNEMATITGQKALVTRAKK AIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTVGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------ARSDQEGKALLQELGMPFMSRIG-K--TPVLIPEKVTVD-L--- -D-G--L-IVTVKGPKGELKRLM--PE-G--VSFDKKD-NT--VVV----S-P-TTNKIHSR-QRHGLCRALIANMVEGV TQGFSKKLEIVGVGS--RAQVKG-KN--LVVS--AGYSHPVEMIP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYHDERILRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVATVKDALPNMG--------VKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNYTKIVSLAPEVIST-L--NTLKSNSGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FEIINLDKLVNLDSLVKK-GLIFLK---------ILG--NGK-V-N-V-K-LTV- QAHAFTKVAKQKIEDAGGSC-K---QHR--GRM---RGVA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYI------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGDD ITEEIAKEAMRLAQYKLPVKTKF-IRKLQTQKRHRRLRRSV---IGDATRPRLSVFRSNNHIYAQVIDD---S--AQKTI CSASTV-DKEL-REKS----DKLPSDCNSSSIVGKLLANR--AIKKG-IKQVIFDRGGNLYH--GRVKALADAAREAGLE F-------------------------------------------------------------TKT-AIAHGNYVRGSASK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNY-GMDPSTLIISSAWANNGPVMKRYRPRAQGRAFSIKKQTCHISISVESKMRIKTGDLVKVINGK------DK-GKT GEVLKTIPLEN--RVV--VKGINLRTKHVK----PT--QE-GET-GRILTEEASLHASNVM-FFSKDK-------NL--T --SKIEYFI---DK--------QGKKR---RLKKTG---EVI--MGHKIHPSGLRLG--IT-QEHRSKWFA------TSK T--YPILLQEDFKIRTFI--QKKYG-----AAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRAGIQKTVR INVVEVER---VDADAFLLAEYISQQLEKRVAFRRTIRMALQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTTTTI-PGSKMSLSIAKVLQKEGFISDIN EEG----E---G----YKSQIILSLKYS---GKN-------K--FPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGIGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCEKIIQTADTTSASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRLIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSRTTRYKAHDPE--NTCALGDRVKIRETRPLSAHKRWAIQEILNKT------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNT---DNDKS----VIKTWSRASTILPLMIGHTIAVHNGKTHIPVFITE-QMIGH KLGEFAPTRTYRGHI------R---DK----KGA------KS >CYANO_Prochlorococcus_marinus_MIT_9313 Concatenation of 2 sequences MAIRTFRPYTPGTRTRVVTDFNE-VTGR------------KP-ERSLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRIVDFR-R--NK-HGIPAKVAAIHYDPHRKAHLALLFYT-DGEKRYILAPAGIAIGQQLISGP-E-SP-IETGNALPLS AIPLGSSVHNVELYAGRGGQMARTAGSSAQVMAK--EGDYVALKLPSTEVRLVRHECYATLGEVGNSEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-DQGR---------AIPVTLIEAGPCR ITQLK----TSE----I--DGY--AAVQIGF-------GD--TINK----------PSKGHLK----------------- ---SG-EVLLKHLREYRV--------EGLEGL-----EL---GA-AITV--G-S-FEAGQKVDVSGDTMGRGFAGYQKRH GFSR-GPMSHGS-KNHRE-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKRTTRGLTILKVDSNRN---------------- ----------LLVVKGS-VPGKPGALLNIR-MAECVVHD-WQGKEA-GKASLELKVS----KE-TT-AVDLMHRAVLRQQ AHSRQGTASTLTRAE--------VR-GGGRKPY---------KQKGTGRAR--------QGT---IR-TP----LR---- PGGGIIFGPK-P-RTYNLAMNRKERRLALRTALMARIED-------------------VIVVKDF--GNSLK-V------ --PKTRLII--LSTPS--E---IIRRSVRNLEKVK-L---------------IAADQLNVFDLLHANS----LVLSEEAL AKIQMSLKQRYRETI----QPKLLKDLSLSNIHEVPKVLKITVNRGLG-EAAQNAKSLEASITELATITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQLIFPEIS-----FDKI DAIRGMDITIVTS-----------------------ARTDEEGQSLLREMGMPFMSRIG-K--NPIPIPDKVAVT-L--- -D-G--L-AVSVKGPKGELSRTL--PE-G--VSVSQVE-NT--IVV----T-P-TSQKRKSR-ERHGLCRSLVANMVEGV SKGYTRKLELIGVGS--RAQVKG-KK--LVVS--AGFSHPVEMDP-P-E-GVTFAVE--N-NTNVTVSG-ADKELVGNEA AKIRAIR------PPEPY---KGKGIRYEGERILRKAGK----------MIQQESFLTVADNSGAKRIQCIRVLG-SNRR Y--AHVGDVIVAAVKDAMPN-M-------SVKKSEVVKAVVVRTKATLRRDTGNSIRFDDNAAVLIN-EDKN-PRGTRVF GPVARELR-ERNFTKIVSLAPEVILR-L--DSLKANVGA-RRRKMRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FTTVNVAALINLDTLVKN-GVVTLK---------VLG--NGE-L-K-V-K-LTI- QAAAFTATARSKIEAAGGTC-K---QQR--GRM---RGVA-TRGNTIAFG----------EFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGAE ITEDIAKEAMRLAQYKLPIKTKF-IRKQQTQKRHRRLRRHL---KGTAQRPRLAVFRSNNHIYAQVIDD---E--AQNTL CAASTL-DKDLRTSLK----ADG-SSCDASNAVGDLVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKSLADAAREAGLQ F-------------------------------------------------------------TTTIAKAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPASLVIAQASADMGPSMKRYRPRAQGRAFAIKKQTCHISIAVAAKMRIHKGDTVQVITGK------DK-GKT GEVLRTLPIEN--RVI--VQGVNIRTRHVK----PT--QE-GES-GRIVTEEASVHASNVM-LYSNKK-------KI--A --SRVELVV---EK--------DGKKR---RLKKTG---ELI--MGHKIHPTGLRLG--IT-QEHRSRWYA------T-S K-MYPILLQEDDRIRRFI--HKKYG-----AAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRTGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATKVASTTYGVLGIKVWIFMANHDPISDMLTRIRNASEKRHQTTRV-PASRMSRSIAKVLQQEGFISEIS EEG----E---G----VRTHLVLELKYS--GKHR-------H---PTIRSMQRVSKPGLRIYKNTRALPKVLGGLGMAII STSKGVMSDRDARKQGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLCS PHVDKDSR-EHFETRTHRRIIDIYNPSAKTIDALMKLDLPSGVDIEVKLLKERLGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDAG--NTCRVGDRVRITETRPLSRSKRWTVAEVLSHS------------------------------- -MGRSL-KKGPFIAD-SLLRKLEKQNA---DDDKS----VIKTWSRASTILPMMIGHTIAVHNGRSHVPVFITE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Prochlorococcus_marinus_MIT_9515 Concatenation of 2 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITGS------------KP-ERSLIVSKHRNKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-RNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGIKVGQNVISGD-S-VP-IEDGNAMPLS VMPLGSSVHCVELYAGRGAQMVRSAGASAQLMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNAEIRNTSLGKAGRT -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKAALGLKTR-KKNKPSN-N-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-DDGN---------AVPVTLIEAGPCR VTQLK----TQS----L--DGY--TAIQIGY-------GV--SLSK----------PEKGHLK----------------- ---SG-KELLKHLKEFKV--------EENSSY-----EI---GK-EITV-TN---FEVGQKVDISGKSMGRGFSGYQKRH GFSR-GPMSHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKITTKGLLVVKIDDQKN---------------- ----------LLVVKGS-VPGKPGSIVNIR-MTTLETLK-WDGKKV-GKVSIDLKVA----KE-TS-SSDLIHRAVLRQL ANQRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGVIFGPK-P-RSYNLDMNRKERRLALRTALMSRVDD-------------------IKAVEDF--GSTLN-Q------ --PKTSLVI--LDSPS--E---VIKKSINNIAKVK-L---------------IAADQLNVFDILNANK----LVIGQSAI NKIQMTLKTRYKETI----RPKLLKDLGLKNIHQVPKVIKVNVNRGLG-EAASNSKALEASLNEMATITGQKALVTRSKK AIAGFKIREGMAIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTLGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------ASNDQEGKALLKELGMPFMSRIG-K--SPVQIPDKVSVD-I--- -N-G--L-TITVKGPKGELKRLM--PE-G--VDFVQKE-NQ--IVV----T-P-STTKRYSR-ERHGLCRTLISNMVQGV TDGYSKKLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEMTP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYQDERIIRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVVVASVKDALPNMG--------VKKSDVVKAVIVRTRHTLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVIST-L--NTLKSNLGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FEIVNLSKLVNIDSLVKK-KLLFLK---------ILG--NGV-V-K-V-K-LKV- QAHAFTKVAQEKIESAGGSC-K---QHR--GRM---KGIA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGEE ITEEIAKEAMRLAQYKLPVKTKF-IRKLQTQKRHKRLRRYL---IGNKIRPRLAVFRSNNHIYAQVIDD---D--AQQTI CSASTV-DKELKEDSD----KLS-PNCSSSTIVGKLLAKR--AIKKG-IKQVIFDRGGNLYH--GRVKALADAARDAGLN F-------------------------------------------------------------TKK-AIAHGKYIRGSASK VRRVLDQIRGKSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNL-GMEPSSLVISSASADNGPVMKRFRPRAQGRAFSIKKQTCHISISVESKMRIKTGDLVKVINGK------EK-GKT GEVLKTIPLEN--RVV--VKGINLRTKHVK----PT--QE-GES-GRILTEEASLHASNVM-FFSKDK-------NI--V --SKIEFFI---DK--------EGKKR---KLKKTG---ELI--MGNKINPTGLRLG--IT-QEHRSKWFA------TSK T--YPILLQEDYKIRNFI--QKKYS-----SAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAYLLAEYIAQQLEKRVAFRRTIRMALQRAQRA-GVLGLKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRAEVDYALREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTSTSI-PASRMILSIAKVLQKEGFIADIN EEG----E---G----YESKIVLGLKYS--GKNR-------F---PTIRSMQRVSKPGLRVYKNTKGLPKVLGGLGVAIV STSKGVMSDRDARKQGIGGEVLCYVYLAQQKIRIRLKAFDRRMLDLSCDKIIQTADTTAASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSKTTRYKAHDPE--NSCAMGDRVKIKETRPLSAHKRWAIEEILNKT------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNT---ENDKS----VIKTWSRSSTILPVMIGHTIAVHNGKAHIPVFITE-QMIGH KLGEFAPTRTYRGHL------R---DK----KGA------R- >CYANO_Prochlorococcus_marinus_NATL1A Concatenation of 2 sequences MAIRSFKPYTPGTRSRVVTDFSE-VTSS------------KP-ERSLVVSKHRKKGRNNRGVITCRH-RGGGHKRL---- YRIVDFR-R--NK-HGVSAKVAAIHYDPHRNARLALLFYS-DGEKRYILAPADITVGQEVISGP-D-AP-IETGNALPLS SMPLGSSVHCVELYPGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--VGRAGPVTP---WGKAALGLKTR-KKNKPSN-K-YVLRKR --------------------------------MSL---G-ILGKKLGMSQLFD-DQGR---------AVPVTLIEAGPCR ITQLK----SAD----T--DGY--AAVQIGF-------QL--IINK----------PSKGHLK----------------- ---SG-NDLLRHLREYRV--------ENSSEF-----EL---GA-SITV--D-D-FEKGQKVDVSGDTMGRGFAGYQKRH GFSR-GPMSHGS-KNHRL-PGSIGAG-TTPG-RVYPGKRMAGRMGGKKVTTRALEILKIDTNHN---------------- ----------LLVVKGS-VPGKPGSLLNIRMMTNCTVLD-WQGKEA-GESSIDLKTA----KE-SS-AADLLHRAVLRQQ AHSRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RKYNLEMNRKERRLALRTALMSRISD-------------------AKIIKDF--GSKLE-V------ --PKTSLII--LNKPS--E---IIKRSIKNLEKVK-L---------------ISADQLNVFDLLNANS----LVIGEDAL STIKMSLKTRYRETI----RPKLLKDLGLKNVHQVPKVQKVTLNRGLG-EAATNSKALEASLKEMATISGQKALVTRAKK AIATFKIRQGMPIGCSVTLRGDRMYAFLERFINLALPRIRDFRGVSP-KSFDGRGNYTIGVKEQLIFPEIT-----FDKV DTIRGMDITIVTS-----------------------ASSDEQGKALLSEMGMPFMSRTG-K--KPISLPEKVDVK-F--- -E-G--L-SITVKGPKGELQRTL--PN-G--VSLSKDE-NF--IFV----K-P-INEKRQSR-EMHGLCRSLVANMVEGV SNGFTKKLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEVVP-P-E-GITFKVE--N-NTNVIVTG-PDKELVGNEA AKIRAIR------PPEPY---KGKGIKYQGELIIRKAGK----------MIQQETFLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVASVKDAMPNMG--------VKKSDVVKAVVVRTRATMRRETGNSIRFDDNAAVLIN-DDQN-PRGTRVF GPVARELR-ERNFTKIVSLAPEVIIK-L--ESLQSNKGS-RRKKMRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPILNVSRLVNLDLLVKE-GILTLK---------ILG--NGN-L-E-V-K-LTV- QAAAFTASAKKKIEEVGGSC-K---QQR--GRM---RGVA-TRGNKIAFG----------QFALQAQ--DCGWVTSRQIE ASRRAMTRYV------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGDE ITETIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHKRLRRNL---SGTESRPRLAVFRSNNHIYAQIIDD---D--AQNTI CAASTL-DKDL-KASL----KVNAGSCDASTAVGELVAKK--ALSKG-IKQVIFDRGGNIYH--GRVKALAEAARVAGLN F-------------------------------------------------------------KTT-AQAHGRYIRGSASK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTEPITKVLRSAVAN----A- ENNL-GLDPSSLMISTATADMGPPMKRYRPRAQGRAFAIKKQTCHISISVSAKMKIRKGDTVQVISGK------DK-GKT GEVLKTLPYEN--RVL--VQGINQRTKHVK----PS--QE-GET-GRIETKEFPLHASNVM-IYSTKE-------KV--A --SKVEIFV---DK--------DGKKR---RLKKTG---ELI--MGHKIHPTGIRLG--IT-QEHRSKWYA------PSK T--YPLLLQEDDRIRTFI--KKKYV-----AAGISDVLIARKA-D-QLEVELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVEK---VDADAYLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRAEIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHEKTKV-PASRMSLSIAKVLQSEGFIAEIN EEG----E---G----FRKQLILGLKYT--GKHR-------S---PIIRSMQRVSRPGLRIYKNTRGLPKVLGGLGIAII STSNGVMSDRDARKQGVGGEVLCYVCIAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKEMVGTVVSDKMQKTVVVAVENRFPHPIYQ KIISRTTRYKAHDAE--NHCKVGDRVRIKESPPISAHKRWTVTDVLVKG------------------------------- -MGRSL-KKGPFISD-SLLRKIEKQNS---NDDKA----VIKTWSRASTILPLMIGHTIAVHNGKSHIPVFITE-QMVGH KLGEFAPTRTYRGHI------R---DK----KGA------R- >CYANO_Prochlorococcus_marinus_NATL2A Concatenation of 2 sequences MAIRSFKPYTPGTRSRVVTDFSE-VTSS------------KP-ERSLVVSKHRKKGRNNRGVITCRH-RGGGHKRL---- YRIVDFR-R--NK-HGVSAKVAAIHYDPHRNARLALLFYS-DGEKRYILAPADITVGQEVISGP-D-AP-IETGNALPLS SMPLGSSVHCVELYPGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--VGRAGPVTP---WGKAALGLKTR-KKNKPSN-K-YVLRKR --------------------------------MSL---G-ILGKKLGMSQLFD-DQGR---------AVPVTLIEAGPCR ITQLK----SAD----T--DGY--AAVQIGF-------QL--IINK----------PSKGHLK----------------- ---SG-NDLLRHLREYRV--------ENSSEF-----EL---GA-SITV--D-D-FEKGQKVDISGDTMGRGFAGYQKRH GFSR-GPMSHGS-KNHRL-PGSIGAG-TTPG-RVYPGKRMAGRMGGKKVTTRALEILKIDTNHN---------------- ----------LLVVKGS-VPGKPGSLLNIR-MTNCTVLD-WQGKEA-GESSIDLKTA----KE-SS-AADLLHRAVLRQQ AHSRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIIFGPK-P-RKYNLEMNRKERRLALRTALMSRIPDA----------------K---IIKDF--GSKLE-V------ --PKTSLII--LNKPS--E---IIKRSIKNLEKVK-L---------------ISADQLNVFDLLNANS----LVIGEDAL STIKMSLKTRYRETI----RPKLLKDLGLKNVHQVPKVQKVTLNRGLG-EAATNSKALEASLKEMATISGQKALVTRAKK AIATFKIRQGMPIGCAVTLRGDRMYAFLERFINLALPRIRDFRGVSP-KSFDGRGNYTIGVKEQLIFPEIT-----FDKV DTIRGMDITIVTS-----------------------ASSDEQGKALLSEMGMPFMSRTG-K--KPISLPEKVDVK-F--- -E-G--L-SITVKGPKGELKRTL--PN-G--VSLSKDE-NF--IFV----K-P-INEKRQSR-EMHGLCRSLVANMVEGV SNGFTKKLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEVVP-P-E-GITFKVE--N-NTNVIVTG-PDKELVGNEA AKIRAIR------PPEPY---KGKGIKYQGELIIRKAGK----------MIQQETFLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVIVASVKDAMPNMG--------VKKSDVVKAVVVRTRATMRRETGNSIRFDDNAAVLIN-DDQN-PRGTRVF GPVARELR-ERNFTKIVSLAPEVIIK-L--ESLQSNKGS-RRKKMRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPILNVSRLVNLDLLVKE-GILTLK---------ILG--NGK-L-E-V-K-LTV- QAAAFTASAKNKIEEVGGSC-K---QQR--GRM---RGVA-TRGNKIAFG----------QFALQAQ--DCGWVTSRQIE ASRRAMTRYV------KRGGQIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGDE ITEAIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHKRLRRNL---SGTESRPRLAVFRSNNHIYAQIIDD---D--AQNTI CAASTL-DKDL-KASL----KVNAGSCDASTAVGELVAKK--ALSKG-IKQVIFDRGGNIYH--GRVKALAEAARVAGLN F-------------------------------------------------------------KTT-AQAHGRYIRGSASK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTEPITKVLRSAVAN----A- ENNL-GLDPSSLMISTATADMGPPMKRYRPRAQGRAFAIKKQTCHISISVSAKMKIRKGDTVQVISGK------DK-GKT GEVLKTLPYEN--RVL--VQGINQRTKHVK----PS--QE-GET-GRIETKEFSLHASNVM-IYSTKE-------KV--A --SKVEIFV---DK--------DGKKR---RLKKTG---ELI--MGHKIHPTGIRLG--IT-QEHRSKWYA------PSK T--YPLLLQEDDRIRTFI--KKKYL-----AAGISDVLIARKA-D-QLEVELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVEK---VDADAYLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARSEWTREGRVPL- -HTLRAEIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHEKTKV-PASRMSLSIAKVLQSEGFIAEIN EEG----E---G----FRKQLILGLKYT--GKHR-------S---PIIRSMQRVSKPGLRIYKNTRGLPKVLGGLGIAII STSNGVMSDRDARKQGVGGEVLCYVCIAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKEMVGTVVSDKMQKTVVVAVENRFPHPIYQ KIISRTTRYKAHDAE--NHCKVGDRVRIKESPPISAHKRWTVTDVLVKG------------------------------- -MGRSL-KKGPFISD-SLLRKIEKQNS---NDDKA----VIKTWSRASTILPLMIGHTIAVHNGKSHIPVFITE-QMVGH KLGEFAPTRTYRGHI------R---DK----KGA------R- >CYANO_Prochlorococcus_marinus_pastoris_CCMP1986 Concatenation of 2 sequences MAIRKFKPYTPGTRQRVVTDFSE-ITGS------------KP-ERSLIVSKHRNKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--DK-KNINAKVAAIHYDPHRNARLALLFYE-DGEKRYIIAPAGIKVGQNVISGE-G-VP-IEEGNAMPLS SMPLGSNVHCVELYAGRGAQMVRSAGASAQLMAK--EGEYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGKA-P--IGRAGPVTP---WGKAALGLKTR-KKNKPSN-K-LVVRRR --------------------------------MSI---G-ILGKKLGMSQLFD-KDGN---------AVPVTLIEAGPCR VTQLK----TQP----L--DGY--TAIQIGY-------GV--SLSK----------PEKGHLK----------------- ---SG-EILLKHLKEYRV--------EENSSY-----EI---GK-EITV----TNFEVGQKVDISGKSMGRGFSGYQKRH GFSR-GPMSHGS-KNHRA-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKITTKGLLVVKIDDQKN---------------- ----------LLVVKGS-VPGKPGSIVNIK-MTTLETLK-WDGKKA-GKVSIDLKVA----KE-TS-SADLIHRAVLRQL ANKRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGVIFGPK-P-RSYNLDMNRKERRLALRTALMSRISD-------------------FKTVEDF--GSTLD-Q------ --PKTSLVI--LDNPS--D---VIKKSINNLEKVK-L---------------IAADQLNVFDILNANK----LVIGQSAI NKIQMTLKTRYKEAI----RPKLLKDLGLKNIHQVPKVIKVNVNRGLG-EAASNSKALEASLNEMATITGQKALVTRSKK AIAGFKIREGMAIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNP-KSFDGRGNYTLGVKEQLIFPEIS-----FDKI DSIRGMDITIVTS-----------------------ASTDQEGKALLKELGMPFMSRIG-K--SPVQIPEKVSVD-I--- -K-G--L-SITVKGPKGELKRLM---P-E-GVNFDQKE-NQ--IVV----T-P-ATTKRYSR-ERHGLCRTLISNMVQGV TEGYEKKLEIVGVGS--RAQVKG-KN--LVVS--AGYSHPVEMTP-P-D-GITYKVE--S-NTNVTVSG-IDKEIVGNEA AKIRSIR------PPEPY---KGKGIKYQDERIIRKAGK----------MIQQETYLTVADNSGAKRLQCIRVLG-SNRR Y--AHVGDVVVASVKDALPNMG--------VKKSDVVKAVIVRTRHTLRRNTGNSIRFDDNAAVLIN-EDKN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVIST-L--NTLKSNTGS-RKKKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FEIVNLSKLVNIDSLVKK-KLLFLK---------ILG--NGE-V-K-V-K-LKV- QAHAFTKVAKEKIEAAGGSC-K---QHR--GRM---KGIA-SKGNTIAFG----------QFALQAQ--DCGWVTARQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVVKP-GRILFEM--GGEE ITEEIAKEAMRLAQYKLPVKTKF-IRKLQTQKRHKRLRRYL---IGSTARPRLAVFRSNNHIYAQVIDD---D--AQQTI CSASTV-DKELKEDKE----KLS-SNCSSSSIVGKLLAKR--AMKKG-VKEVIFDRGGNLYH--GRVKALADAARDAGLN F-------------------------------------------------------------TKT-AIAHGKYIRGSASK VRRVLDQIRGKSYRDALIMLEFM---------------------------------PYRSTDPITKVLRSAVAN----A- EHNL-GMDPSSLVISSASADNGPVMKRFRPRAQGRAFSIKKQTCHISISVESKMRIKTGDLVKVINGK------EK-GKT GEVLKTIPLEN--RVV--VKGVNLRTKHVK----PS--QE-GES-GRILTEEASLHASNVM-FFSKDK-------NL--I --SKIEYFI---DK--------EGKKR---RLKKTG---ELI--MGNKINPTGFRLG--IT-QEHRSKWFA------TSK T--YPTLLQEDDKIRTFI--QKKYS-----SAGISDVLIARKA-D-QLELELKTARPGVIVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAYLLAEYIAQQLEKRVAFRRTIRMALQRAQRA-GVLGLKVQVGGRLNGAEIARTEWTREGRVPL- -HTLRAEVDYALREANTTYGVLGIKVWVFMSNHDPISDMLTRIRNASQKKHTSTAI-PASKMSLSIAKVLQKEGFITDIN EEG----E---G----YKSQIVLGLKYS---GKN-------K--FPTIRSMQRVSKPGLRVYKNTKGLPKVLGGLGVAIV STSKGVMSDRDARKQGIGGEVLCYVYLTQQKIRIRLKAFDRRMLDLSCDKIIQTADTTAASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERIGTVVSDKMDKTVVVAVINRYPHPTYK KIVSKTTRYKAHDPE--NSCVLGDRVKIKETRPLSAHKRWAIEEILNKT------------------------------- -MGRSL-KKGPFIAD-SLLKKVEKQNT---DNDKS----VIKTWSRSSTILPVMIGHTIAVHNGKAHIPVFITE-QMIGH KLGEFAPTRTYRGHL------R---DK----KGA------R- >CYANO_Synechococcus_elongatus_PCC_6301 Concatenation of 2 sequences MGIRAFRPYTPGTRERVVSDYAE-ITRN------------EP-EKSLLVSKHRRKGRNNRGVITCRH-RGGGHKRL---- YRIIDFK-R--DK-RNVPGKIVSIEYDPNRNARISLVYYE-DGEKRYILTPAGVHVGTPIIAGD-E-TP-IEVGNAMPLQ NIPLGTTVHNVELVAGKGGQIVRAAGASAQVVAK--EGNYVALKLPSTEVRLVRKECYATIGAVGNAEVRNTSLGKAGRK -RWL-----GRR-P-EVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGRKTR-KKNKQSD-C-LIQRRR --------------------------------MSI---G-ILGTKLGMTQIFD-ESGK---------AVPVTVIQAGPCP ITQIK----TVA----T--DGY--NAIQIGF-------LE--VLSK----------PELGHLK----------------- ---AG-APPLRHLLEYRV--------PSTDGL-----EL---GQ-ALTA--D-R-FEAGQKVDVQGHTIGRGFTGYQKRH GFAR-GPMSHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGRSGNDKTTIRGLTVVRVDADRN---------------- ----------LLLVKGS-VPGKPGALLNIT-MVDYVIQD-WQGQTA-GNITVELRVA----KE-ES-AAAIVHRALIRQL ANARQGTHASKTRSE--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSVKMNRKERRLALRTALISRSAD-------------------LVVVQEF--ADQIS-R------ --PKTRLLI--TADRD--Q---NVELSVRNLPNVK-L---------------ITATNLNIFDLLNADR----IVSTSAAL EKIQMSLKTKYRDII----VPKLMKEFGYTNIHQVPKVVKVTINRGLG-EGAQNAKALESSLAEIAKIAGQKPVVTRAKK AIAGFKIRAGMPVGLMVTLRGDRRDAFLERLINLSLPRIRDFRGISP-RSFDGRGNYTLGLREQLIFPEIT-----YDSI DQIRGMDITIVTS-----------------------ANSDEEGRALLRELGMPFMSRIG-K--RPIPIPAKVSVA-I--- -D-G--R-LVSVKGPKGELSREL--PS-G--VVVTQED-GN--IIV----S-R-ADESRLAR-QRHGLSRTLVANLVEGV DSGFQKRLEIIGVGY--RAQVQG-TT--LILN--VGYSNPVQIEP-P-E-GIQFVVE--N-NTNVVVSG-ISKEVVGNTA ARIRAVR------PPEPY---KGKGIRYAGEVVLRKAGK----------MIQQETYLNVADNSGARKLMCIRVLG-SNRR Y--AGVGDVIIAVVKDALPN-M-------PVKKSDVVRAVVVRTKKSLRRDSGNVIRFDDNAAVIIN-ADGN-PRGTRVF GPVARELR-DRNFTKIVSLAPEVIMK-L--DNLAPQPGA-KKRKRRVG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLVNVGALVTLESLMAV-GIVTLK---------ILG--DGE-L-S-V-S-LSV- SAAAFTATAQQKIEAAGGSI-K---QQR--GRM---TGKA-TRGNTLAFG----------NFGLQAL--ECSWITARQIE ASRRAMTRYT------RRGGKIWIRIFPDKPITMRPAETRMGSGK---------GNPEFWVAVVKP-GRVLFEI--GG-E VAEETAREAMRLASHKLPIKTKF-IRRESTRRRHRRVRRTI---VGTPARPRLSVFRSNNHIYAQVIDD---A--AGHTL AAASSL-DPDL-RQSL----TSG-GNQQASAAVGKLIAER--AQAKG-VTTVVFDRGGNLYH--GRVKALAEAAREAGLE F-------------------------------------------------------------ANE-VKAIARYIRMSPSK VRRVLDQLRGRSYREALILLEFM---------------------------------PYKSCEPILKVLRSAVAN----A- EHNQ-GLDPTQLVISQAYADMGPSLKRFRPRAQGRAYQIRKQTCHITIAVAPSVHVKKGDTVQVIAGK------DK-GTV GEVLQVFPKTS--RVL--VKGVNLRTKHVK----PR--QE-GES-GQIVVEEASIHSSNVQ-LYSTTQ-------KV--A --SRVAYTF---TE--------DGKVR---KLKKTG---EII--MGQKINPVGFRLG--VT-QEHRSRWFA------DPN R--YPQLLQEDKKIRDYV--RKNLS-----NAGIADIRVERKA-D-QVELEIRTARPGVVVGRGGAGIDTLREGLQALIR INVIEVER---VDADAALLGEYIAQQLERRVAFRRCVRQAIQRAQRA-GVQGIKIQVAGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYTTATTTYGILGIKVWVFMAVNDPIADMLTRIRNASEARHATTVV-PASRLARSIAEVLKREGFIADFE ESG----E---G----VQRHLVLSLKYK--GKNQ-------Q---PIIKALKRVSKPGLRVYSNRRDLPRVLGGIGIAII STSQGIMTDRDARRQGVGGEVLCYVWLQQQKIRIRLKAFDRRLLDTSCDRIVETANRTNATAIGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIEDRTAHPKYG KIVVRTKRYKAHDED--NRAKTGDRVRIQETRPLSRTKRWTVAEILESV------------------------------- -MARSL-KKGPFVAD-HLLRKVEKLNA---KGDKQ----VIKTWSRASTILPQMIGHTIAVHNGRQHVPVYVTE-QMVGH KLGEFAPTRTFRGHT------K--DKK----AGR-------- >CYANO_Synechococcus_elongatus_PCC_7942 Concatenation of 2 sequences MGIRAFRPYTPGTRERVVSDYAE-ITRN------------EP-EKSLLVSKHRRKGRNNRGVITCRH-RGGGHKRL---- YRIIDFK-R--DK-RNVPGKIVSIEYDPNRNARISLVYYE-DGEKRYILTPAGVHVGTPIIAGD-E-TP-IEVGNAMPLQ NIPLGTTVHNVELVAGKGGQIVRAAGASAQVVAK--EGNYVALKLPSTEVRLVRKECYATIGAVGNAEVRNTSLGKAGRK -RWL-----GRR-P-EVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGRKTR-KKNKQSD-R-LIQRRR --------------------------------MSI---G-ILGTKLGMTQIFD-ESGK---------AVPVTVIQAGPCP ITQIK----TVA----T--DGY--NAIQIGF-------LE--VLSK----------PELGHLK----------------- ---AG-APPLRHLLEYRV--------PSTDGL-----EL---GQ-ALTA--D-R-FEAGQKVDVQGHTIGRGFTGYQKRH GFAR-GPMSHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGRSGNDKTTIRGLTVVRVDADRN---------------- ----------LLLVKGS-VPGKPGALLNIT-MVDYVIQD-WQGQTA-GNITVELRVA----KE-ES-AAAIVHRALIRQL ANARQGTHASKTRSE--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSVKMNRKERRLALRTALISRSAD-------------------LVVVQEF--ADQIS-R------ --PKTRLLI--TADRD--Q---NVELSVRNLPNVK-L---------------ITATNLNIFDLLNADR----IVSTSAAL EKIQMSLKTKYRDII----VPKLMKEFGYTNIHQVPKVVKVTINRGLG-EGAQNAKALESSLAEIAKIAGQKPVVTRAKK AIAGFKIRAGMPVGLMVTLRGDRRDAFLERLINLSLPRIRDFRGISP-RSFDGRGNYTLGLREQLIFPEIT-----YDSI DQIRGMDITIVTS-----------------------ANSDEEGRALLRELGMPFMSRIG-K--RPIPIPAKVSVA-I--- -D-G--R-LVSVKGPKGELSREL--PS-G--VVVTQED-GN--IIV---SR-A--DESRLAR-QRHGLSRTLVANLVEGV DSGFQKRLEIIGVGY--RAQVQG-TT--LILN--VGYSNPVQIEP-P-E-GIQFVVE--N-NTNVVVSG-ISKEVVGNTA ARIRAVR------PPEPY---KGKGIRYAGEVVLRKAGK----------MIQQETYLNVADNSGARKLMCIRVLG-SNRR Y--AGVGDVIIAVVKDALPN-M-------PVKKSDVVRAVVVRTKKSLRRDSGNVIRFDDNAAVIIN-ADGN-PRGTRVF GPVARELR-DRNFTKIVSLAPEVIMK-L--DNLAPQPGA-KKRKRRVG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLVNVGALVTLESLMAV-GIVTLK---------ILG--DGE-L-S-V-S-LSV- SAAAFTATAQQKIEAAGGSI-K---QQR--GRM---TGKA-TRGNTLAFG----------NFGLQAL--ECSWITARQIE ASRRAMTRYT------RRGGKIWIRIFPDKPITMRPAETRMGSGK---------GNPEFWVAVVKP-GRVLFEI--GG-E VAEETAREAMRLASHKLPIKTKF-IRRESTRRRHRRVRRTI---VGTPARPRLSVFRSNNHIYAQVIDD---A--AGHTL AAASSL-DPDL-RQSL----TSG-GNQQASAAVGKLIAER--AQAKG-VTTVVFDRGGNLYH--GRVKALAEAAREAGLE F-------------------------------------------------------------ANE-VKAIARYIRMSPSK VRRVLDQLRGRSYREALILLEFM---------------------------------PYKSCEPILKVLRSAVAN----A- EHNQ-GLDPTQLVISQAYADMGPSLKRFRPRAQGRAYQIRKQTCHITIAVAPSVHVKKGDTVQVIAGK------DK-GTV GEVLQVFPKTS--RVL--VKGVNLRTKHVK----PR--QE-GES-GQIVVEEASIHSSNVQ-LYSTTQ-------KV--A --SRVAYTF---TE--------DGKVR---KLKKTG---EII--MGQKINPVGFRLG--VT-QEHRSRWFA------DPN R--YPQLLQEDKKIRDYV--RKNLS-----NAGIADIRVERKA-D-QVELEIRTARPGVVVGRGGAGIDTLREGLQALIR INVIEVER---VDADAALLGEYIAQQLERRVAFRRCVRQAIQRAQRA-GVQGIKIQVAGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYTTATTTYGILGIKVWVFMAVNDPIADMLTRIRNASEARHATTVV-PASRLARSIAEVLKREGFIADFE ESG----E---G----VQRHLVLSLKYK--GKNQ-------Q---PIIKALKRVSKPGLRVYSNRRDLPRVLGGIGIAII STSQGIMTDRDARRQGVGGEVLCYVWLQQQKIRIRLKAFDRRLLDTSCDRIVETANRTNATAIGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLVKERVGVVVSDKMDKTVVVAIEDRTAHPKYG KIVVRTKRYKAHDED--NRAKTGDRVRIQETRPLSRTKRWTVAEILESV------------------------------- -MARSL-KKGPFVAD-HLLRKVEKLNA---KGDKQ----VIKTWSRASTILPQMIGHTIAVHNGRQHVPVYVTE-QMVGH KLGEFAPTRTFRGHT------K--DKK----AGR-------- >CYANO_Synechococcus_sp_CC9311 Concatenation of 2 sequences MAIRTFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVSKHRRKGRNNRGVITCRH-RGGGHKRQ---- YRLVDFR-R--NK-HGVTAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGISIGQTVVSGT-E-VP-IEIGNAMPLS AIPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECFATLGEVGNAEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-K-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-EQGK---------AVPVTLIEAGPCR ITQLK----SSE----T--DGY--QAVQIGF-------GE--IINK----------PAKGHLK----------------- ---SG-EDLVRHLCEYRV--------DDLDGI-----QL---GG-AVTV-GD---FAAGQKVDVSGDTMGRGFAGLQKRH GFSR-GPMTHGS-KNHRQ-PGSIGAG-TTPG-RIYPGKRMSGRYGGKKITTRGLTILKIDSERN---------------- ----------LLVVKGS-VPGKPGSLLNIR-MANCIVRD-WQGKEA-GKASLDLKVA----KE-AS-ALDLMHRAVLRQQ AHSRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---VR-TP----LR---- PGGGIIFGPK-P-RSYNLAMNRKERRSALRTALMARIED-------------------LVVVKDF--ATTLT-T------ --PKTKLII--LTNPS--E---AVRRSIRNLETVK-L---------------IAADQLNVFDLLHANK----LVVGEDAL AKIQMSLKQRYRETI----QPKLLKDLSLSNIHEVPKVLKVTVNRGLG-EAATNAKSLEASVNELAQITGQKVVITRAKK AIAAFKIRQGMPIGCAVTLRGDRMYAFLERFINLALPRIRDFRGVSP-KSFDGRGNYTVGVREQIIFPEIS-----FDKI DAIRGMDITIVTS-----------------------ARTDEEGRALLREMGMPFMSRIG-K--NPIPIPDKVNVT-L--- -S-G--L-AVTVKGPKGELKRTL--PS-G--VSVNQVD-NS--IVV----A-P-TSTKRSSR-ERHGLCRTLVANMVIGV SQGYSKKLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEVVP-P-E-GITFTVE--N-NTNVTVSG-TDKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQETFLTVADNSGAKRIQCIRVLG-TNRR Y--AHVGDVIVATVKDAMPNMG--------VKKSDIVKAVVVRTKATMRRDTGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERSFTKIVSLAPEVILR-L--ESLKPNKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FTLLNVSALVNLDSLVKD-GIVTLK---------ILG--NGE-L-K-A-K-LTV- QAAAFTASARAKIEAAGGTC-K---QQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGEE ITPEIAKEAMRLAQYKLPLKTKF-IRKQQTQKRHRRLRRHL---SGTANRPRLAVFRSNSHIYAQLIDD---E--AQSTL CSASTL-DKDL-RSSL----KTNCSSCDASVAVGDLVAKR--AIAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLQ F-------------------------------------------------------------ATT-AQAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPASLIISQATADMGPSMKRYRPRAQGRAYAIKKQTCHISIAVAA-MRLRKGDTVQVIAGK------DK-GKT GEVLRTLPNEN--RVI--VEGLNMRTRHVK----PT--QE-GET-GRIVTEEASLHASNVM-FYSTAK-------KV--A --SRIELIT---EK--------DGKKR---RLKKTG---EVI--MGHKIHPTGLRLG--IT-QEHRSRWYA------SSK S--YPALLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEDLRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRAEIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHESTKV-PASRMSRSIAKVLQQEGFIAEIS EQG----E---G----VRTELVLGLKYS--GKHR-------Q---PTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERVGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDED--NACRVGDRVRITETRPLSRHKRWAIAEVLSQS------------------------------- -MGRSL-KKGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGRTHVPVFVTE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Synechococcus_sp_CC9605 Concatenation of 2 sequences MAIRNFRPYTPGTRTRVVTDFSE-ITSR------------KP-ERTLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRVVDFR-R--NK-HGVPAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVQVGQTVVSGP-D-AP-IENGNAMPLS SVPLGSAVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEMRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-Q-YVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-EQGR---------AVPVTLIEAGPCR ITQLK----NDD----T--DGY--SAVQIGF-------GE--TINK----------PAQGHLK----------------- ---SG-EGLLRHLREYRV--------DSVEGL-----EL---GG-AITV-GD---FEAGQKVDVSGDTVGRGFAGYQKRH GFSR-GPMTHGS-KNHRE-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKITTRGLTILKVDSEHN---------------- ----------LLVVKGS-VPGKPGALLNIR-MASCVVRD-WQGKEA-GKATLDLKVA----KE-TT-AVDLMHRAVLRQQ AHARQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LK---- PGGGIIFGPK-P-RTYNLAMNRKERRLALRTALMARIDD-------------------VTVVQDF--GASLE-A------ --PKTRLIV--LTNPS--D---VVRRSVRNLEKVK-L---------------ISADQLNVFDLLHANA----LVLGEEAL ATIQMSLKKRYRETI----QPKLQKDLSLTNIHEVPKVLKVTVNRGLG-EAAANAKSLEASVNELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGDRMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARSDEEGRALLREMGMPFMSRIG-K--NPVPVPEKVTVS-L--- -D-G--L-TVKVKGPKGELERTL--PE-GVSVSVSQDN-NT--IVV----S-P-TSTKRISR-ERHGLSRTLVANMIEGV SNGYSKALEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEMEA-P-E-GITFKVE--N-NTRVIVSG-IDKELVGNEA AKVRAIR------PPEPY---KGKGIKYEGERILRKAGK----------MIQQESYLTVADNSGAKRIQCIRVLG-TNRR Y--AHVGDVIVAAVKDAAPNMG--------VKKSDVVKAVVVRTKATMRRETGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERSFTKIVSLAPEVILR-L--DSLKSNKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLLNVSALVNLDSLVKD-GIVTLK---------MLG--NGE-L-TAK-K-LTV- QAAAFTSSALTKIEAAGGTC-K---QQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGDE ITPEIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHI---TGTSDRPRLAVFRSNNHIYAQVIDD---A--AQSTL CSASTV-DKELRTGLK----APA-GSCDASVAVGELVAKR--AMAKG-IQQVVFDRGGNLYH--GRIKALADAAREAGLQ F-------------------------------------------------------------APT-AQAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPSSLVISSATADMGPSMKRYRPRAQGRAYQIKKQTCHISIAVAAKMRIRKGDTVQVIAGK------DK-GKT GAVLRTLPNEN--RVV--VEGVNMRTRHEK----PT--QE-GET-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---RLKKTG---EVL--MGHKINPTGLRLG--IT-QEHRSRWYA------SSK N--YPALLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTKI-PASRMTRSIAKVLQQEGFISEIS EQG----E---G----IRTELVLALKYS-----G-------KHRLPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARREGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCEKIIETADNTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLVKERIGTVVSDKMEKTVVVAVESRFPHPIYQ KTVSRTTRYKAHDED--NTCRVGDRVRITETRPMSRQKRWAIAEVLSHS------------------------------- -MGRSL-KKGPFIAD-SLLRKVEKQND---NDDKS----VIKTWSRASTILPMMIGHTIAVHNGRTHVPVFITE-QMVGH KLGEFAPTRTFKGHI------R---DK----KGG------R- >CYANO_Synechococcus_sp_CC9902 Concatenation of 2 sequences MAIRKFRPYTPGTRTRVVTDFSE-VTGR------------KP-EKTLVVSKHRKKGRNNRGVITCRH-RGGGHKRL---- YRLVDFR-R--NK-HGVTAKVAAIHYDPHRNARLALLFYS-DGEKRYILAPAGVQVGQTVVSGP-E-VP-IENGNAMPLS SVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-Q-YVLRKR --------------------------------MSI---G-ILGKKLGMSQLFD-EQGR---------AVPVTLIEAGPCR ITQLK----NDD----T--DGY--AAVQIGF-------GE--TINK----------PSKGHLK----------------- ---SG-EDLLRHLREYRV--------DNVDGL-----EL---GG-SITV-SD---FEAGQKVDVSGDTMGRGFAGLQKRH GFSR-GPMTHGS-KNHRQ-PGSIGAG-TTPG-RIYPGKRMSGRYGGKKTTTRGLTILRIDSDRN---------------- ----------LLVVKGS-VPGKPGALLNIK-MASCVVRD-WQGKEA-GKATLDLKVA----KE-AS-AVDLMHRAVLRQQ AHMRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---VR-TP----LR---- PGGGIIFGPK-P-RSYNLAMNRKERRSALRTALMARIDD-------------------ITVVKDF--GTSLE-A------ --PKTRLIV--LTNPS--E---MVRRSVRNLDKVK-L---------------ISANHLNVFDLLHANS----LVVGEDAL TTIQMSLKKRYRETI----QPKLLKDLSLTNIHEVPKVMKVTINRGLG-EAATNAKSLEASVKELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGDRMYAFLERLINLALPRIRDFRGVSA-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARSDEEGRALLSEMGMPFMSRIG-K--NPVPVPDKVTVS-L--- -D-G--L-TVKVKGPKGELERTL--PE-G--VSVSQEA-NT--IVV----A-P--TSTKRISRERHGLSRTLVANMIEGV HNGYSKALEIVGVGS--RAQVKG-TT--LVVS--AGYSHPVEMPA-P-A-GITFKVE--N-NTRVIVSG-IDKELVGNEA AKVRAIR------PPEPY---KGKGIKYEGEHILRKAGK----------MIQQESFLTVADNSGAKRIQCIRVLG-TNRR Y--AHVGDVIVAAVKDAMPNMG--------VKKSDVVKAVVVRTKATLRRETGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERSFTKIVSLAPEVILR-L--DSLKANKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLLNVSALVNLDSLVKD-GIVTLK---------MLG--NGE-L-T-V-KNLTV- QASAFTTSARTKIEAAGGTC-K---QQR--GRM---RGVA-TRGNTIAFG----------EFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGEE ITPEIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHI---TGTSNRPRLAVFRSNNHIYAQLIDD---A--AQSTL CSASTV-DKEL-RSGL----KNNAGSCDASVAVGALVAKR--AIAKG-IEQVVFDRGGNLYH--GRIKALADAAREAGLQ F-------------------------------------------------------------AAT-AQAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- ENNL-GLDPASLVISSASADMGPSMKRYRPRAQGRAFQIKKQTCHISIAVAVKMRIRKGDTVQVIAGK------DK-GKT GAVLRTLPNEN--RVI--VEGVNMRTRHEK----PS--QE-GES-GRIVTEEASLHASNVM-LYSTDK-------KV--A --SRVEIVV---EK--------DGKKR---KLKKTG---EVL--MGHKIHPTGLRLG--IT-QEHRSRWYA------SSK T--YPSLLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEDLRAGIQKTVR INVVEVER---VDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVGKTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTKV-PASRMTRSIAKVLQQEGFISEIN EEG----E---G----FRAELVLSLKYS-----G-------KHRLPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARREGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAASAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLVKERVGTVVSDKMEKTVVVAVETRFPHPIYQ KTVSRTTRYKAHDED--NSCRVGDRVRITETRPMSRQKRWAIAEVLSHS------------------------------- -MGRSL-KKGPFIAD-SLLRKLEKQND---NDDKS----VIKTWSRASTILPMMIGHTIAVHNGKSHIPVFITE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Synechococcus_sp_JA-2-3Ba(2-13) Concatenation of 2 sequences MGIRTLRPYTPSTRHMTVSDFEE-LSRD------ENGKRPRP-EKSLLQFIHRKKGRNNRGVITCRH-RGGGHKRL---- YRIIDFR-R--DK-RGIPGTVKTVEYDPNRSAHICLVEYE-DGEKRYILAPRNLQVGSTIMAGP-E-AP-FEIGNAMPLE RIPLGTVVHNVELYPGRGGQMVRAAGAGAQVVAR--EGKYVSLKLPSGEVRMIRGECYATIGQLGNVDHNNISLGKAGRS -RWL-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRSTPVTP---WGKPTLGYKTR-KRNKPSN-K-FIVRGR --------------------------------MAL---G-ILGRKVGMTQIFS-PEGL---------AIPVTVVQAGPCT VTQIK----TQA----T--DGY--NAIQLGY-------LP--TLTR----------AQRGHLK----------------- ---AGVTELLRHLREFRV--------DQPEAY-----QL---GQ-KITV--E-M-FSPGQLVDVAGTSIGRGFAGYQKRH HFGR-GPMSHGS-KNHRR-PGSIGAG-TTPG-RVFPGMRMAGRLGGGRVTTRKLQLVQVDPERD---------------- ----------LLVIKGC-VPGVEGGLLEIT-MASCVVKN-WQGETV-GSAELSLKVA----RP-ET-AAHILYLALRRQM TNARQGNAHTKTRAE--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----LW---- RKGGVIFGPR-K-REYNLAMNRKERQLALRTALQSRVED-------------------LIVVEDF--QEQLN-P------ --PKTRLLI--VAERS--E---AVERAVRNIARVK-L---------------IGLDQINVFDLLNVDW----VLITVSAL EQLKQRLQILYNTVI----VPKLQKELGYTNIHQVPRLEKIVINRGLG-EASQNAKALESSIAEISAITGQRPVITRAKK AIASFKIRKGMPVGLMVTLRRERMYAFLDRLINVALPRIRDFRGVSP-KAFDGRGNYTLGIREQLIFPEIN-----YDSV DQLRGMDISIVTT-----------------------AKTDEEGRALLKAFGMPFMSRIG-R--RPIALPAKVEIQ-I--- -D-G--Q-HIAVKGPKGQLSRSL---P-P-LITVQQNA-QM--LTV----S-R-LNDSRPAR-QLHGLCRTLVANMVDGV SKGFERRLELVGVGY--RAAIQG-SK--LVLN--VGYSHPVEIPF-P-P-GIQIAVE--G-NNIIVVSG-TDKELVGNTA ARIRAVR------PPEPY---KGKGIRYLGEQVRRKAGK----------MIQQQTMLTVADNTGARKMMCIRVLS-SGRR Y--ASLGDVIIGVVKDALPN-M-------PVKKSDVVKAVVIRTVDTVRRPDGMCIRFDDNAAVIIN-NDGN-PRGTRVF GPVARELR-EKNFTKIISLAPEVLMR-L--EDIRPQAGS-TRRRRRLG-RGVSAGQ-GASCGKGMRGQKARKGGS-T--- -RPGF-E-GGQTPLYRRLPKLKH--FPRVNLRALVSLESLMER-GIVTLK---------ILG--DGE-V-S-V-P-LTI- RAAAITASAKVKVEAAGGRV-K---QQR--GRM---KGKA-TRGNRINFG----------EYGLVAL--EPAWITARQIE ASRRAMTRYV------RRGGQIWIRIFPDKPVTQRAAETRMGSGK---------GNPEYWVCVVKP-GRILFEM--GG-- VAEPIAREAMRLAAQKLPIKVKF-VRKITTQRRHRRIRRKV---FGTAERPRLAVFRSHRHIYAQVIDD---V--AQHTL ASASTL-DREL-REKF--KETGT-ATQEAAALVGRSVAER--ALQMG-ISRVVFDRGGKLYH--GRVQALAEAAREAGLQ F-------------------------------------------------------------SPE-VKAVARYIRMSPFK VRRVLDQIRGRTYADALILLEFM---------------------------------PYAACEPVRKVLRSAVAN----A- EHNN-GLDPRDLVISQAYADQGPVLKRFRPRAQGRAYPIRKRTCHITIAVRPKMRIKQGDTVQVISGD------DK-GKI GEVLRVFPERN--MVL--VEGVNIVTYHRK----PQ--RE-GES-GRIETKEAPIPVCKVM-AYSKKQ-------EV--A --SRIGYQI---TA--------DGKVR---VLKKTG---EIL--MGQKIHPTGFRLG--VI-KEHRSRWFA------D-P A-RYPALLQEDDQIRTYL--TKQLS-----SAGLADIQIER-KAD-QIDLEIRAARPGVVVGRGGSSLETLRQGLQKEIR INVVEVTR---ADAEATLLAENIAQQLERRIAFRRIVRQVIQRAQRA-GVQGIKIQIAGRLNGAEIARTEWTREGRIPL- -HTLRADIDYAEHLAHTTFGIIGVKVWVFAHTNDTIADMLTRIRNATMARHESVAV-PATRMTRSIARVLHEEGFVSEWK EEG----E---G----IQARVVLRLKYK---GKG-------RNCRPIINGLKRVSRPGLRVYRNHKELPRVLGGIGIAII STSNGIMTDREARKQGIGGEVLCLVYLTQQKIRIRLKAYDHRLLDTSCDKIVDTARRTDAVPVGPIPLPTRRRIYCVLRS PHIDKDSR-EHFETRTHRRIIDIYSPSSKTIDALMKLDLPAGVDIEVKLVREKIGIVVSNKMQKTVVVAVENRVAHPKYG KIVVKTKKFKAHDEE--NRCQEGDLVRITETRPLSRTKRWQVAEILREV------------------------------- -MGRSL-KKGPFVDA-KLLLKVEKMNE---RNEKH----LIKTWSRASTILPVMIGHTIAVHNGKQHVPIYITD-QMVGH KLGEFVPTRTFRGHA------G--SDK----KAA------RR >CYANO_Synechococcus_sp_JA-3-3Ab Concatenation of 2 sequences MGIRTFRPYTPSTRHMTVSNFEE-LSRD------ENGKRPRP-EKSLLQFIHRKKGRNNRGVITCRH-RGGGHKRL---- YRIIDFR-R--DK-RGIPATVKTIEYDPNRSARICLVEYE-DGEKRYILAPRNLEVGATIMAGP-D-AP-FELGNAMPLE RIPLGTVVHNVELYPGRGGQIVRAAGAGAQVVAK--EGKYVSLKLPSGEVRMIRGECYATIGQVGNVDHSNLSLGKAGRS -RWL-----GRR-P-HVRGSVMNPVDHPHGGGEGKA-P--IGRSTPVTP---WGKPTLGYKTR-KRNKPSN-K-FIVRGR --------------------------------MAL---G-ILGRKVGMTQIFS-PEGL---------AIPVTVVQAGPCT VTQIK----TQA----T--DGY--NAVQLGY-------WP--TLTR----------AQRGHLK----------------- ---AGVTELLRHLREFRV--------DQPEAY-----QL---GQ-KITV--E-I-FSPGQLLDVAGTSIGRGFAGYQKRH HFGR-GPMSHGS-KNHRR-PGSVGAG-TTPG-RVFPGLRMAGRMGGCRVTIRKLQLVQVDPERN---------------- ----------LLIIKGS-VPGVEGGLLEIT-MASCVVKN-WQGETV-GSAELSLKVA----RP-ET-ASHILYLALRRQM TNARQGNAHTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RKGGVIFGPR-K-REYNLAMNRKERQLALRTALQSRVED-------------------LIVVEDF--QDQLN-P------ --PKTRLLI--VAERS--E---AVERAVRNIARVK-L---------------IGLDQLNVFDLLNVDW----VLITTSAL EKLKQRLQILYNTVI----VPKLQKELGYTNIHQVPRLEKIVINRGLG-DASQNAKALESSIAEISAITGQRPVITRAKK AIASFKIRKGMPVGLMVTLRRERMYAFLDRLINIALPRIRDFRGVSP-KSFDGRGNYTLGIREQLIFPEIN-----YDSV DQIRGMDISIVTT-----------------------AETDEEGRALLKEFGMPFMSRIG-K--RPIALPAKVEVQ-I--- -E-G--Q-QISVKGPKGELSRSL---P-P-LIAVHQEA-QT--LKV----S-R-VNESRPAR-QLHGLCRTLVANMVDGV SRGFERRLELVGVGY--RASTQG-NK--LILN--VGYSHPVEIPF-P-P-GIQIAVE--G-NNVIVVSG-IDKELVGNTA ARIRAVR------PPEPY---KGKGIRYVGEQVRRKAGK----------MIQQQTMLTVADNTGARKLMCIRVLS-SGRR Y--ASLGDVIVGVVKDALPN-M-------PVKKSDVVKAVVIRTVDTVRRPDGMCIRFDDNAAVIIN-DDGN-PRGTRVF GPVARELR-EKNFTKIISLAPEVLMR-L--EDIRPQPGS-TRRRRRLG-RGIAAGQ-GASCGKGMRGQKARKGGG-P--- -RPGF-E-GGQTPLYRRLPKLKH--FPRINLRALVSLESLMDL-GIVTLK---------ILG--DGE-V-G-V-P-LTI- RAAAITPSARAKVEAAGGRV-K---QQR--GRM---KGKA-TRGNRINFG----------EYGLVAL--EPAWITARQIE ASRRAMARYV------RRGGQIWIRIFPDKPVTQRPAETRMGSGK---------GNPEYWVCVVKP-GRILFEM--GG-- VPEATAREAMRLAAQKLPIKVKF-VRKAATQRRHRRIRRKV---FGTPERPRLAVFRSHRHIYAQVIDD---V--AQHTL VSASTL-DREL-REAF--KDIGT-ATREAAAVVGRSVAQR--ALQAG-ICQVVFDRGGKLYH--GRVQALAEAAREAGLQ F-------------------------------------------------------------SPE-IKAVARYIRMSPYK VRRVLNQIRGRTYADALILLEFM---------------------------------PYAACEPVRKVLRSAVAN----A- EHNN-GLDPRDLVISKAYADQGPTLKRFRPRAQGRAYPIRKRTCHITIAVRPKMRIKKGDTVQVISGD------DK-GKI GEVLQVFPERN--MVL--VEGVNIVTYHRK----PQ--RE-GES-GRIETKEAPIHACKVM-LYSKKQ-------EV--A --SRIGYQI---TA--------DGKVR---VLKKTG---EIL--MGQKIHPTGFRLG--VI-KEHRSRWFA------D-P A-RYPALLREDDLIRAYL--TKQLS-----SAGLADIQIERKA-D-QIDLEIRAARPGVVVGRGGSGLDALRQGLQKEIR INVVEVTR---ADAEAVLLAENIAQQLERRIAFRRIVRQVIQRAQRA-GVQGIKIQIAGRLNGAEIARTEWTREGRIPL- -HTLRADIDYADHIAQTTFGVIGVKVWVFAHTNDTIADMLTRIRNATMARHESVAV-PATRMTRSIARVLHEEGFVSDWK EEG----E---G----IHAQLVLRLKYK--GKGR-------K---PIINGLKRVSRPGLRVYCNHKELPRVLGGIGIAII STSNGIMTDRDARKQGIGGEVLCYVYLTQQKIRIRLKAYDHRLLDTSCDKIVDTARRTEAVPVGPIPLPTRRRLYCVLRS PHTDKDSR-EHFEVRTHRRIIDIYSPSSKTIDALMKLDLPAGVDIEVKLAREKIGVVVSNKMQKTVVVAVENRVAHPKYG KIVVKTKKFKAHDEE--NRCQEGDLVRITETRPLSRTKRWRVAEIIREV------------------------------- -MGRSL-KKGPFVDA-KLLLKIEKMNE---RNEKH----MIKTWSRASTILPVMIGHTIAVHNGKQHVPIYITD-QMVGH KLGEFVPTRTFRGHA------G--SDK----KAA------RR >CYANO_Synechococcus_sp_PCC_7002 Concatenation of 2 sequences MGIRSFRPYTPGTRQATVSDFSE-ITKS------------KP-EKSLTKYKHRKKGRNNRGVITCRH-RGGGHKRL---- YRLIDFR-R--DK-RDITAQVTAIEYDPNRNARIALVQYE-DGEKRYILQPAGLGVGDTIIAGE-E-AP-YEIGNALPLY KIPLGTEIHNIELYAGRGGQMVRSAGAFAQLVAK--EGDYVTIKLPSKEVRMVRKECYATIGKVGNAEARNLKLGKAGRT -RHL-----GRR-P-QVRGSVMNPVDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGKKTR-KKKKQSS-S-LIVRRR --------------------------------MSL---G-ILGTKLGMTQIFDNETGT---------AIPVTVVQAGPCT VTQIK----TSE----T--DGY--TSVQIGY-------GD--VLTK----------PQLGHLK----------------- ---AD-AAPLRHLKEYRL--------DDVSGY-----EL---GQ-AITA--N-I-FEAGQVVDVSGNTIGRGFAGYQKRH NFKR-GNMTHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGRYGGTKITVRKLEVVRVDEEKN---------------- ----------LLLIKGA-IPGKAGNLLSIA-MVNCAVKN-WQGEEV-GQANLDFKVA----KE-EN-AAHIVHRALVRQL NNARQGTSSTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- KGGGVIFGPK-P-KEYNLKMNRKERRLALRTAFHSRNED-------------------LIVVENF--AEQFA-A------ --PKTKLLV--LAEMT--D---NVYLSARNIASVK-M---------------VPADGLNIFDILNAGK----IVVTSEAL AKIQQRLKTLYQDSI----VPKLTEQFGYSNVHEVPKLVKISVNRGLG-EASSNAKAMESSIKELSTITGQRPVITRAKK AIAGFKIREGMPVGVMVTLRSEKMYSFLDRLISLALPRIRDFRGISP-KSFDGRGNYSLGIREQLIFPEID-----YDSI DQIRGMDISIITT-----------------------ARTDEEGRALLREMGMPFMSRIG-K--KPIPIPDKVTVT-L--- -N-G--A-NVAVKGPKGSLERTL--PE-K--VTVTQED-NT--IVV----S-P-VDNSRTAR-ERHGLCRTLVANMIEGV SQGYSKQLEIIGVGY--RAQVQG-NK--LTLN--VGYSKPVEMQM-P-E-GVTAAMG--EKNTQVIISG-IDKEVVGNTA AKVRAVR------PPEPY---KGKGIRYQGEYIRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLT-GNCR Y--GGIGDQIIAVVKEAIPN-M-------GVKKSDVVRAVIVRTRQPLRRASGMSIRFDDNAAVIIN-AEGN-PKGTRVF GPVARELR-DKNFTKIVSLAPEVIMK-L--SNLSPKAGS-KKRRRRVG-RGIAAGQ-GASCGFGMRGQKSRSGTG-T--- -KAGF-E-GGQMPLYRRVPKLKH--FTIVNVGQLVTLESLMAA-GIVTLK---------VLG--DGE-L-S-V-A-LKV- TAAAFSNGAKAKIEAAGGSC-K---QHR--GRM---RGMA-YRGNNIQFG----------DYALQAV--EPSWITARQIE AARRAMTRYI------KRGGKIWIRIFPDKPITMRPAETRMGSGK---------GNPEFWVAVVKP-GRIMFEM--NG-- VAEPIAREAMRLAAQKLPIKTKF-IRKQLTQRRHFRIRRRV---EGTGDRPRLAVFRSHKHIYAQVIDD---E--KQHTL VAASTL-DKDL-KGEL----ASG-GNISASTAVGNLIAKR--ALEKG-ITKVVFDRGGNLYH--GRVKALADAAREAGLD F-------------------------------------------------------------QTE-VKAIARYIRMSPIK VRRVLDQIRGRSYREALIILEFM---------------------------------PYRACEPVLKVLRSAVAN----A- EHNE-GLDPADLVVSAAFADAGPVLKRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKTGDTVQVISGR------DK-GKV GEVIKTLPKSS--KVV--VKDVNIRTKHVK----PQ--QE-GES-GQIQTFEAPIHSSNVM-HYSEKE-------KV--A --SRIGYQL---TE--------DGKVR---VLKKTG---EVI--MGQKIHPVGFRLG--IT-KEHLSRWYA------DPK Q--YPALVQEDYKIRQHI--DANLN-----NAGISKVLIERKA-D-QVDLEIHTARPGVVVGRGGSGIEALRTGLQDVIR INVVEVNR---VDADAALIAEYIVQQLERRVSFRRVVRQAVQRAQRA-EVQGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYSYKTAQTIYGILGIKVWIFMAANDTISDMLTRIRNACMVQHDNTKV-PMTRMTRNIAEVLKDEGFIENYT EAG----E---G----IEKHLVISLKYK--GRNR-------Q---PIIQKLQRVSKPGLRVYSNHKDLPRVLGGIGIAII STSKGVMTDRQARKEGIGGEILCYVWLQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLTKERVGMVVSDKMDKTVIVAVENRSPHPKYK KIVVKTKRFKAHDEE--NKCKVGDRVRIRETPPTSKTKRWTIAEILNQ-------------------------------- -MGRSL-KKGPFIAD-SLLKKIEKLNA---SGDKQ----VIKTWSRASTILPQMVGHTIAVHNGRQHVPVFVSE-QMVGH KLGEFAPTRTFKGHA------K--SDK----KAR------R- >CYANO_Synechococcus_sp_RCC307 Concatenation of 2 sequences MGIRSFRPYTPGTRTRVVSDFSE-VTRR------------KP-ERSLVVAKHRRKGRNNRGVITCRH-RGGGHKRL---- YRIVDFR-R--DK-HGVVARVAAIQYDPHRNARLALLYYT-DGEKRYILHPAGVQVGQEVVAGP-E-AP-IEVGNALPLS AIPLGSAVHNVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRK -RWL-----GRR-P-EVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-K-FVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-DEGR---------AVPVTVIEAGPCR ITQVK----TPT----N--DGY--SAVQVGF-------GD--VVNQ----------PAKGHLK----------------- ---SG-EDLLRHLKEYRV--------DSTDGV-----EL---GS-SVTV--D-A-FEPGQKVDVSGDTMGRGFSGYQKRH GFSR-GPMTHGS-KNHRE-PGSTGAG-TTPG-RIYPGKRMAGRYGGTKTTVKGLVVLKVDSERN---------------- ----------LLVVKGS-VPGKPGALLSIR--MNCVIQD-WQGKEA-GKASLDLKVA----KE-TS-AADLIHRAVVRQL ANARQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIVFGPK-P-RSYELDMNRKERRLALRTALMSRSED-------------------MVVVKAF--GDKLA-K------ --PKTKLMV--LADIS--D---NVRLSVRNLPQLK-L---------------IAADQLNVFDLLNAQK----LVVSEDAL TKIQMSLKKRYREAI----QPKLLKDLNFSNLHQVPKVVKVTVNRGLG-EAAQNAKSLEASVEEIATITGQKPVVTRAKK AIAGFKIRQGMPIGVAVTLRGDRMYAFLERLINLALPRIRDFRGVSE-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARNDEEGQALLREMGMPFMSRIG-K--NPVPIPEKVSVE-I--- -S-G--L-TVKVKGPKGELERVL--PD-G--VSVSQAD-NA--VTV----S-P-SDTSRRSR-ERHGLCRTLVANMVEGV SKGFSKKLEIIGVGY--RAQVKG-KK--LVVS--AGYSHPVEMDA-P-E-GVTFAVE--N-NTLVTVSG-ADKELVGNEA AKVRGIR------PPEPY---KGKGIKYQGERILRKAGK----------MIQQETFLNVADNSGAKRIQCIRVLG-TNRR Y--AHVGDVIVATVKDAMPNMG--------VKKSDIVKAVVVRTKHTMRRETGNAIRFDDNAAVIIN-DDKN-PRGTRVF GPVARELR-ERSFTKIVSLAPEVILT-L--QSLKPQKGA-RRRKMRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FTLVNVGELVTRDSLTEA-GILTLK---------VLG--DGE-L-K-V-K-LTV- HAAAFTASAREKIEAAGGSC-K---QQR--GRM---RGIA-TRGNTIAFG----------TFALQAQ--ECGWITSRQIE ASRRAMTRYT------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEI--GGPE ITEELAKEAMRLAQYKLPVKTKF-LRKEQTQKRHRRLRRHL---EGTPERPRLAVYRSNEHIYAQVIDD---A--AQHTL AAASSL-DKDL-RTSL----NNG-ANCDASTAVGQLVAKR--AIAKG-IQQVVFDRGGNLYH--GRVKALAEAAREAGLQ F-------------------------------------------------------------SPQ-ALAHGRFVRGSVSK VRRVLDQIRGRSYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNM-GLDPSNLVVSMASADMGPTMKRYRPRAQGRAYQIKKQTCHISIGVTPKMRIRKGDTVQVIAGK------DK-GKT GEVLRTLPWEN--RVV--VQGVNLRTRHVK----PA--QE-GES-GRIVTEEASLHASNVM-VYSTDK-------KV--A --SRVEIVV---DK--------DGKKR---KLKKTG---ELL--MGHKINPTGLRLG--IT-QEHRSRWYA------PAR T--YPTLLQEDERIRKFV--NKKYA-----SAGISSVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRAGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRVIRMAVQRAQRA-GVLGLKIQVGGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANTDPISDMLTRIRNACEKRHQTTNI-PLSRMNRSIAKVLEQEGFIDQFS EAG----E---G----VQKHLVLSLKYS---GKQ-------K--VPTIRSVQRVSKPGLRIYTNRRDLPKVLGGLGVAII STSKGVMSDRDARKEGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADHTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRLIDIFNPSSKTIDALMKLDLPSGVDIEVKLVKERVGTVVSDKMEKTVVVAVENRFPHPIYK KTVSRTTRYKVHDED--NRCQVGDRVRITETRPLSRSKRWAVAEIMTTK------------------------------- -MGRSL-KKGPFVAD-SLLRKVEKLNA---AGEKP----VIKTWSRASTILPMMIGHTIAVHNGKAHVPVFVTE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Synechococcus_sp_WH_7803 Concatenation of 2 sequences MAIRSFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVSKHRRKGRNNRGVITCRH-RGGGHKRQ---- YRVVDFR-R--NK-HGVPAKVAAIHYDPHRNARLALLFYT-DGEKRYILAPAGVTVGQTVISGP-D-AP-IEDGNAMPLS SVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEIRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-K-FVLRKR --------------------------------MSI---G-ILGKKLGMSQLFD-EQGK---------AVPVTLIEAGPCR ITQLK----TTE----T--DGY--SAVQIGF-------GE--TVNK----------PAKGHLK----------------- ---SG-EGVLRHLSEYRV--------DDVNGL-----EL---GG-AVTV-SD---FEAGQKVDVSGDTMGRGFAGYQKRH GFSR-GPMTHGS-KNHRE-PGSTGAG-TTPG-RIYPGKRMAGRYGGKKTTTRGLTILKVDSDRN---------------- ----------LLVVKGS-VPGKPGALLNIR-MANCVVRD-WQGKET-GKASLDLKVA----KE-TT-ALDLMHRAVLRQQ AHTRQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIVFGPK-P-RSYNLAMNRKERRLALRTALMARIDD-------------------VTVVKDF--GTSLE-A------ --PKTRLIV--LGTPS--E---VLRRSVRNLEKVK-L---------------IAANQLNVFDLLHANA----LVLGEEAL ATIQMSLKQRYRETI----QPKLLKDLSLSNVHEVPKVVKVTVNRGLG-EAAQNAKSLEASVNELAQITGQKVVVTRAKK AIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARTDEEGRALLREMGMPFMSRIG-K--SPIPIPDKVSVS-L--- -D-G--L-AVTVKGPKGELKRTL--PD-G--VTVNQVD-NT--IVV----A-P-TSEKRQSR-ERHGLCRTLVANMIEGV SKGYSKKLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEMLA-P-E-GITFAVE--N-NTNVTVSG-TDKELVGNEA AKIRAIR------PPEPY---KGKGIKYAGERILRKAGK----------MIQQESFLTVADNSGAKRIQCIRVLG-TNRR Y--AHVGDVIVAAVKDAMPNMG--------VKKSDVVKAVVVRTKATLRRDTGNSIRFDDNAAVIIN-DDKN-PKGTRVF GPVARELR-ERNFTKIVSLAPEVILR-L--ESLKSNKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLVNVSALVSLDSLVKD-GIVTLK---------ILG--NGE-L-K-T-K-LTV- QAAAFTASARTKIEAAGGTC-K---QQR--GRM---RGVA-TRGNTIAFG----------QFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKPVTMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGDE ITPEIAREAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHL---SGTADRPRLAVFRSNSHIYAQVIDD---A--AQSTL CSASTL-DKDLRTSLT----ATG-STCDASVAVGELVAKR--ALAKG-IQQVVFDRGGNLYH--GRVKALADAAREAGLQ F-------------------------------------------------------------ATT-AQAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPSTLVISQASADMGPSMKRYRPRAQGRAYAIKKQTCHISIAVASKMRLRKGDTVQVIAGK------DK-GKT GEVLRTLPNEN--RVI--VEGVNMRTRHVK----PT--QE-GES-GRIVTEEASLHASNVM-LYSTAK-------KV--A --SRVELIT---EK--------DGKKR---RLKKTG---EVI--MGHKIHPTGLRLG--IT-QEHRSRWYA------SSK S--YPTLLKEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDADAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHQNTKV-PASRMSRSIAKVLQQEGFIAEIS EEG----E---G----VHTNLVLELKYS-----G-------KHRLPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARKQGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLLKERVGTVVSDKMDKTVVVAVENRFPHPIYQ KTVSRTTRYKAHDEN--NSVRVGDRVRITETRPLSRHKRWAVAEVLSHS------------------------------- -MGRSL-KKGPFIAD-SLLRKVEKQNA---ADDKS----VIKTWSRASTILPMMIGHTIAVHNGKTHVPVFVTE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Synechococcus_sp_WH_8102 Concatenation of 2 sequences MAIRNFRPYTPGTRTRVVTDFSE-VTGR------------KP-ERSLVVSKHRRKGRNNRGVITCRH-RGGGHKRL---- YRVVDFR-R--NK-HGITAKVAAIHYDPHRNARLALLFYA-DGEKRYILAPAGVQVGQTVVSGP-D-AP-IENGNAMPLS AVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAK--EGDYVALKLPSTEVRLVRRECYATLGEVGNSEVRNTSLGKAGRR -RWL-----GRR-P-QVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVTP---WGKPALGLKTR-KRNKPSN-R-YVLRKR --------------------------------MSI---G-ILGKKLGMSQFFD-EQGR---------AVPVTLIEAGPCR ITQLK----SSD----T--DGY--AAVQIGF-------GD--TINK----------PAKGHLK----------------- ---TG-ETLLRHLREYRV--------DGLDGF-----EL---GG-SITV-GD---FEAGQKVDVSGDTIGRGFSGYQKRH GFSR-GPMTHGS-KNHRE-PGSIGPG-TTPG-RIYPGKRMAGRYGGKKITTRGLTILKVDSERN---------------- ----------LLVVKGS-VPGKPGALLNIR-MADCVIRD-WQGKEA-GKATLDLKVA----KE-TT-ANDLMHRAVLRQQ AHARQGTASTLTRSE--------VR-GGGRKPY---------KQKGTGRAR--------QGS---IR-TP----LR---- PGGGIVFGPK-P-RTYNLAMNRKERRLALRTALMARVED-------------------VTVVKDF--GTSLE-A------ --PKTKLIV--LTEPS--D---VVRRSVRNLEKVK-L---------------IAANQLNVFDLLHANA----LVLGEDAL ATIQMSLKKRYRETI----QPKLQKDLSLTNIHEVPKVVKVTVNRGLG-EAAANAKSLEASVNELAQITGQKVVVTRAKK AIAAFKIRQGMPIGCAVTLRGDRMYAFLERLINLALPRIRDFRGVSP-KSFDGRGNYTLGVREQIIFPEIS-----FDKI DAIRGMDITIVTT-----------------------ARSDEEGRALLREMGMPFMSRIG-K--NPVPVPDKVTVS-L--- -D-G--L-TVKVKGPKGELERTL--PD-G--VSVSQDN-NC--IVV----A-P-STSKRFSR-ERHGLCRTLVANMIEGV NNGYSKSLEIVGVGS--RAQVKG-KT--LVVS--AGYSHPVEMEP-P-E-GITFKVE--N-NTKVIVSG-IDKELVGNEA AKVRAIR------PPEPY---KGKGIKYEGERIMRKAGK----------MIQQESYLSVADNSGAKRIQCIRVLG-TNRR Y--AHVGDVIVAAVKDAMPNMG--------VKKSDVVKAVVVRTKATLRRDTGNSIRFDDNAAVIIN-ADNN-PKGTRVF GPVARELR-ERNFTKIVSLAPEVILR-L--ESLKANKGA-RRRKLRKG-RGIAAGQ-GASCGFGMRGQKSRSGRP-T--- -RPGF-E-GGQMPLYRRVPKLKH--FPLLNVSALVNLDSLVKD-GVVTLK---------ILG--NGD-L-TAK-K-LTV- QAAAFTASARTKIEAAGGSC-K---MQR--GRM---RGVA-TRGNTIAFG----------EFALQAQ--ECGWITSRQIE ASRRAMTRYV------KRGGKIWIRIFPDKSITMRAAETRMGSGK---------GNPEFWVAVIKP-GRILFEM--GGAE ITPEIAKEAMRLAQYKLPVKTKF-IRKQQTQKRHRRLRRHL---TGTSDRPRLAVFRSNNHIYAQVIDD---D--AQSTL CSASTV-DKELRAGLE----ANG-GSCDASVAVGELVAKR--AIAKG-IQSVVFDRGGNLYH--GRIKALADAAREAGLQ F-------------------------------------------------------------API-AQAHGRFIRGSVSK VRRVLDQIRGRTYRDALIMLEFM---------------------------------PYRSTGPITKVLRSAVAN----A- EHNL-GLDPASLVISSASADMGPSMKRYRPRAQGRAFQIKKQTCHISIAVAAKMRIRKGDTVQVIAGK------DK-GKT GEVLRTLPNEN--RLI--VEGVNMRTRHEK----PT--QE-GET-GRIVNEEASLHASNVM-LYSTAK-------KV--A --SRVEIVV---EK--------DGKKR---KLKKTG---EVL--MGHKINPTGLRLG--IT-QEHRSRWYA------SSK S--YPALLQEDDRIRKFI--HKKYG-----SAGISDVLIARKA-D-QLEVELKTARPGVLVGRQGSGIEELRSGIQKTVR INVVEVER---VDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRA-GVLGLKIQVSGRLNGAEIARTEWTREGRVPL- -HTLRADIDYATKVASTTYGVLGIKVWVFMANHDPISDMLTRIRNASEKRHETTKI-PASRMTRSIAKVLQQEGFISEIS EQG----E---G----VRTELVLSLKYS-----G-------KHRLPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAII STSKGVMSDRDARREGVGGEVLCYVYIAQQKIRIRLKAFDRRMLDLSCDKIIETADQTAATAIGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKLVKERVGTVVSDKMEKTVVVAVESRFPHPIYQ KTVSRTTRYKAHDED--NSCRVGDRVRITETRPMSRHKRWAIAEVLSHS------------------------------- -MGRSL-KKGPFIAD-SLLRKVEKQND---TDDKS----VIKTWSRASTILPMMIGHTIAVHNGKSHVPVFITE-QMVGH KLGEFAPTRTFKGHI------K---DK----KGG------R- >CYANO_Synechocystis_sp_PCC_6803 Concatenation of 2 sequences MGIRNYRPMTPGTRQASVSDFTE-ITKS------------KP-EKSLTTNRHDQKGRNNRGVITSRH-RGGGHKKL---- YRIIDFK-R--NK-QNIPARVAAIEYDPNRNARIALLFYT-DGEKRYILAPAGLQVGMTVIAGE-E-AP-FEIGNTLPLS RIPLGSEIHNVELVAGRGGQMVRSAGAFAQVVAK--EGDYVTIKLPSKEVRMVRKECVATLGRVSNAEFRNLKLGKAGRK -RHL-----GRR-P-HVRGSVMNPCDHPHGGGEGRA-P--IGRSGPVSP---WGKPALGAKTR-NKKKRSS-A-LIVRRR --------------------------------MSI---G-ILGTKLGMTQIFDQESGI---------SIPVTVVQAGPCP VTQVK----TQD----T--DGY--NAIQVGF-------LP--VLSK----------PELGHLK----------------- ---SN-TDPMRHLKEYRL--------TDAPNL-----QP---GD-AVTA--D-I-FQAGDLVDVAGQSMGRGFAGYQKRH NFRR-GNMTHGS-KNHRL-PGSTGAG-TTPG-RVYPGKRMAGQYGASQVTVRRLTVVRVDAERN---------------- ----------LLIIKGA-LPGKPGTLLNIT-MVDCIVKN-WQGEEV-GNASLTLRVA----KE-EN-AAHIVHRALVRQQ NNARQGNASAKTRAE--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSQKMNRKERRLALRTAIASRADN-------------------MVVVEAF--GDQFS-Q------ --PKTKLLI--LDEIP--E---NVFLSGRNIPYLK-I---------------LRADNLNIYDVLVADT----IVATATAL EKIQQRLKTLYQETI----LPKLQEEFGYKNIHQVPKLTKVTVNRGLG-EASQNAKALESSLTELATITGQKPVVTRARK AIAGFKIREGMPVGVMVTLRSERMYAFLDRLINLALPRIRDFRGISP-NSFDGRGNYSLGIREQLIFPEID-----YDTI DQIRGMDVSIITS-----------------------AQTDEEGRALLKALGMPFMSRIG-K--RPIPLPAKVSVD-I--- -Q-G--S-HLSVKGPKGSLERQL--PE-K--VIVAQEG-ET--ITV---TR-Q--DESRTAR-ERHGLVRTLVANMVDGV AQGFERRLEIQGVGY--RAQAQG-NK--LTLN--VGYSKPVEMTM-P-Q-GIEVKVE--N-NTQVIVSG-IDKELLGNTA AKIRAVR------PPEPY---KGKGIRYQGEYVRRKAGK----------MIQQQTYLNVADNSGARKLMCLRVLT-GNCT Y--GGIGDQIIAVVKDALPN-M-------PIKKSDVVRAVIVRTKQPLRRASGMSIRFDDNAAVIIN-AEGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMN-L--SELSPKDGA-KKRRRRVG-RGIAAGQ-GASCGFGMRGQKSRSGTG-T--- -KAGF-E-GGQMPLYRRLPKLKH--FPLVNVGKLVTLESLMEA-GIVTLK---------VLG--NGE-L-A-V-A-LTV- -HAPCSKAAQAKIEAAGGSV-K---QQR--GRM---RGLA-ERGSTLNFG----------DYALQAT--EPCWITSRQIE AARRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEYWVAVVKP-GRVMFEL--AG-- VSEEVAREAMRLAAQKLPIKTKF-IRKSATQRRHRRLRRHL---SGTSERPRLAVFRSNDHIYAQVIDD---V--AQHTL AAASTL-DPDL-KKSL----SST-ATQEASAEVGKLVAQR--AIAKG-INQVVFDRGGKLYH--GRVKALAEAAREAGLN F-------------------------------------------------------------TAE-VKAIARYVRMSPLK VRRVLDQIRGRSYREALIILEFM---------------------------------PYKACEPVLKVLRSAVAN----A- EHNE-GLEPADLVVSQAFADGGPSLRRFRPRAQGRAYQIRKPTCHITVAVAPKMHVKKGDTIQVISGK------DK-GKV GEVLRTIPSHS--QVV--VKGVNIRTKHVK----PR--QE-GES-GQISSYEAPIHSSKVM-LYSTKE-------KI--A --SRICYTV---TD--------DGKVR---MLKKTG---EII--MGQKIHPVGFRLG--IT-KDHKSCWYA------DPK R--YPELLQEDHKIRQYI--EKTLN-----NAGISDIRIERKA-E-QIELGIHTARPGVVVGRGGSGIEQLREGLQKLIR VNVIEVPN---ADADAALMAEYIGQQLERRVSFRRVVRQALQRAERA-EVKGIKIQVSGRLNGAEIARTEWVREGRVPL- -HTLRADIDYAYRTALTTYGILGIKVWIFMASTDTISDMLTRIRNACAVRHSTTQV-PTTKMTLSIAKVLKSEGFIEDYS ETG----E---G----INKMLVLTLKYK--GKTR-------Q---PLINTLQRVSKPGLRVYSPSKKIPRVLGGIGIAIV STSHGIMTDREARRQGIGGEILCYIWLQQQKIRIRLKAFDRRLLDTSCDKIVDTANRTNAAAVGPIPLPTKRKIYCVLRS PHVDKDSR-EHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKLIKERVGIVVSNKMDKTVVVAVESRSPHPKYG KIVVKTKKFKAHDEE--NQCQEGDKVRIQETRPLSKTKRWQVINIMSHS------------------------------- -MGRSL-KKGPFVAA-SLLRKIDKLND---KGDKQ----VVKTWSRASTILPQMVGHTIAVHNGRQHVPVFVSE-QMVGH KLGEFAPTRTFRSHS------K--SDK----KAR------K- >CYANO_Thermosynechococcus_elongatus_BP-1 Concatenation of 2 sequences MGIRVYRPYTPGVRQKTVSDFAE-ITTD------------KP-EKSLTRGFKRDKGRNNRGVITSRR-RGGGHKRR---- YRIVDFR-RS-SK-LNIPAKVATVEYDPNRNARIALLHYR-DGEKRYILHPRDLTPGTEIIASP-D-AP-IEVGNALPLG KIPLGTSVHNVEITPGRGAQMVRAAGAMAQVVAK--EGDMVTLKLPSGEVRLFRKECYATIGQVGNVEANNISLGKAGRN -RWK-----GRR-P-KVRGSVMNPVDHPHGGGEGRA-P--IGRPGPVTP---WGKPTLGYKTR-KKKKLSD-A-LIVRRR --------------------------------MTV---G-ILGTKLGMTQIFD-EAGR---------SVPITVVQAGPCP ITQIK----TPQ----T--DGY--TAIQVAY-------GE--VLSR----------PERGHLK----------------- ---SQ-TPPMRHLREFRL--------EDVSAY-----QL---GQ-AITV--D-I-FSPGQLVDVRGTSIGRGFAGYQKRH NFKR-GPMAHGS-KNHRL-PGSTGAG-TTPG-RVFPGKRMAGRMGNTAVTIRKLQVMRVDPERN---------------- ----------LILIKGA-LPGKPGALVSIT-MVACVVKD-WQGADS-GEATLDLATA----KP-ET-ASHIVHRALVRQL ANARQGTVSTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSQKMNRKERRLALRTALMSRVED-------------------LIVVQDF--ADHLP-R------ --PKTKLLL--AADIT--E---TVALSARNVPTLK-L---------------LRADQLNVFDLLYADR----IVATTGAI AKIQQRLKDHYNKTV----VPQLMQQFQYKNIHQVPKIVKVTVNRGLG-EAAQNAKALEATLAEIATITGQKPVVTRAKK AIAGFKIRKGMPVGVAVTLRSERMYAFLDRLINLALPRIRDFRGVNP-KSFDGRGNYTLGLREQLIFPEVN-----YDDI DQIRGMDVSIITT-----------------------ANTDEEGRALLKAMGMPFMSRIG-K--RPIPLPKNVTLT-L--- -D-G--Q-QVTVKGPKGQLSRVF--PP-E--VNVVQEG-EA--IVV---KR-R--DDSRPAK-ERHGLCRTLLANMVEGV SQGFTKKLEIQGVGY--RAQLQG-KT--LVLS--MGYSHPVEIVP-P-E-GITLEIKVQQ-GTIVLVSG-IDKELVGNTS ARIRAVR------PPEPY---KGKGIRYMGEFVRRKVGK----------MIQQETYLNVADNSGAKKLLCIRVLG-SNRR Y--GSVGDVIIATVKDATPN-M-------AVKKSDVVRAVIVRTRKSIRRESGMSIRFDDNAAVLIN-QDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-F--QDLHPQAGS-RRRKRRIG-RGIAAGQ-GASGGFGMRGQKSRSGRP-T--- -RPGF-E-GGQNPLYRRLPKLKH--FPLINVGRLVTVQSLLEA-GILTLK---------VLG--DGE-L-N-V-K-LEV- HAAAFSGSARSKIEAAGGVC-K---QQR--GRM---TGVA-SRGNSIHFG----------DYALQAL--EPAWITARQIE AGRRAMTRYI------RRGGKIWIRIFPDKPVTMRPAETRMGSGK---------GSPEYWVAVVKP-GRIMYEI--AG-- VTEEVAREAMRLAAYKMPIKTRF-LRTAARQSRHQRIRRKV---KGTSDRPRLAVFRSHQHIYAQVIDD---T--RHHTL VAASSL-EPEL-RQKL----GKG-STCAASIAVGRLIAER--AKAAG-IERVVFDRGGNIYH--GRVKALADAAREGGLD F-------------------------------------------------------------SPT-ARACAKYVRMSPHK VRRVLDQLRGRTYRDALIMLRFM---------------------------------PYRACEPITKVLRSAAAN----A- THNL-GLDPATLVISQAYADQGPCLKRFRPRAQGRAYQIRKPTCHITIAVAPRMHVKKGDTVQVIAGS------DK-AKV GEVLAVFPKTS--QVI--VKGVNLKTKHLK----PR--QE-GES-GQIITKEAPIHSCKVM-LYSTKQ-------NV--A --SRICYTY---TE--------DGKVR---MLKKTG---EII--MGQKIHPIGFRLG--IT-QDHRSRWYA------DSD R--YPELLQEDHRIRTFI--NQQLA-----NAGIAEVRIERKA-D-QVELQIRTARPGVVVGKGGQGIEELRKQLRQMIK VNVVEVNR---VDAEASLLAEYITQQLERRVAFRRAVRQAIQRAQRA-GIEGIKVQVAGRLNGAEIARTEWTREGRVPL- -HTLRADIDYAYRTARTIYGILGVKVWIFMAVNDTIGDMLTRIRNANLARHQTTTI-PATRMTRSIAQVLKAEGFIRDFE EQG----D---G----VKRHLVVSLKYR--GKQR-------Q---PIITALKRVSKPGLRVYANSRELPRVLGGIGIAII STSNGIMTDREARKQGIGGEVLCYVWALQQKIRIRLKAFDHRLLDTSCDRIVDTAKRTGASPVGPIPLPTRRRIYCVLRS PHVDKDSR-EHFETRTHCRILDIYQPSPKTIDALIKLDLPAGVDIEVKLVKERVGVVVSDKMQKTVVVAVENRAPHPKYG KIVVKTRRYKAHDEN--NEAKVGDRVRIRETRPLSRTKRWVIAEILSPR------------------------------- -MGRSL-KKGPFVAD-HLLRKIEALNE---RNAKE----VIKTWSRASTIVPEMIGHTIAVHNGKQHVPVYITE-QMVGH KLGEFAPTRNFRSHV------K--GDK----KAR------H- >CYANO_Trichodesmium_erythraeum_IMS101 Concatenation of 2 sequences MGIRSYRPYTPSTREHSVSDFAE-VTKS------------RP-EKTLVKFRHRKKGRNNRGVVTCRH-RGGGTKKL---- YRVVDFH-R--NK-HNIPAKVAAIEYDPYRNARIALLHYQ-DGEKRYILHPLGLKVGQLITSGV-N-AP-LEIGNALPLS KIPLGTDVHNVELVPGKGGQMVRSAGAVAQVVAK--EDQYVTIKLPSGERRKVRASCYATLGQIGNIEHRNISLGKAGRN -RWK-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--VGRSGPVTP---WGKPALGMKTR-KKKKQSD-A-LIVQRR --------------------------------MVV---G-ILGTKLGMTQVFEAETGK---------AIPVTVVEAGPCV VTQIK----TEQ----T--DGY--TAVQIGY-------GE--ALTN----------AQEGHLK----------------- ---SG-GTPLRYLREYRV--------DNTGNF-----EL---GQ-QIKV--D-L-FEAGQLVDVTGKSIGKGFAGYQKRH NFRR-GPMAHGS-KNHRL-PGSTGPG-TTPG-RVYPGKKMAGHLGNVRVTTRKLKIVRIDPERN---------------- ----------LLLIKGS-IPGKSGTLISIA-MVDCVVKN-WQGEEV-GQATLNLRVA----KE-ES-AAHIVHRSLRLQM ANNRQGTASTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGGVIFGPK-P-RDYSHKMNRKEKRLALSTAFQSRSED-------------------LIVIEDL--SEQFT-K------ --PKTKVLV--LPEKQ--E---NVYLSGRNIAKLK-I---------------ILANNLNIYDILAADK----IIATVTAI AKIQDTLKKYYYKKI----VPKLIDQFKYKNIHQVPKLVKVTINRGLG-EASQNAKALDSSIKEIATITGQKPVVTRAKK AIAGFKIRQGMPVGVMVTLRSQRMYEFIERLINLALPRIRDFRGINP-KSFDGRGNYSLGVKEQLIFPEIE-----YDKI DQIRGMDISIITT-----------------------AKTDEEGRALLKEMGMPFMSRIG-K--LPIPIPKKVTIT-I--- -E-G--Q-KVTVKGPLGELSRVL--PP-E--IAVKEQE-NT--IIV----K-P-QEQSRRAR-QRYGLCRTLVANMVEGV SKGYEKRLVIQGVGY--RAQVQG-KT--LVLN--VGYSKPVEMPA-P-E-GINIAVE--N-NTNVIVNG-INKELVGNTA AKIRAVR------PPEVY---KGKGVRYAGEVIKLKAGK----------MIQQQSLLNVADNSGARKLMCIRVVG-GNRR Y--AHIGDVIIAVVKDASPN-M-------AVKKSDVVRAVVVRTKKGLRRDSGMSIRFDDNAAVIIN-QDGN-PRGTRVF GPVARELR-DKNFTKIVSLAPEVLMR-L--KDAIPKKGS-QQRGRRVG-RGISAGQ-GASCGKGMRGQKSRSGGS-T--- -RPGF-E-GGQNPLYRRLPKLKG--FPMINVSKLVTLASLIKV-GIITLK---------ILG--DGD-L-N-I-P-LKV- YAAAFTASARSKIEAAGGSC-K---QQR--GRM---RGNA-NSGNKISFG----------QYALQAL--EPSWITSRQIE AARRAMTRYI------RRGGKIWIRVFPDKPVTMRAAETRMGSGK---------GAPEYWVAVVKP-GRIMFEL--GG-- VVEEIAREAMRLASFKLPIKTRF-IRKDSIIKRHRRVRKKV---FGTSERPRLSVFRSNMHIYAQVIDD---T--KQHTL VAASTL-EAEV-KSTI----KSG-ANCDASIQIGKLIAQR--SLEKG-IEKVVFDRGGNLYH--GRVKALAEAAREAGLD F-------------------------------------------------------------NTE-VKAIARYIRMSPFK VRRVLDQIRGISYREALIILEFM---------------------------------PYRSCVPIRKVLCSAVAN----A- ENNK-GIDPDTLVISKAFADQGPCLPRYRPRAQGRAYKIRKPTCHITVAVASKVHVKKGDTVQIIAGK------DK-GKV GEVLKVLPKVS--KVI--VKDVNIITKHVK----PQ--QE-GES-GKIVTTEAPIHSSNVM-LYSTKQ-------KV--A --SRICYTF---TD--------DGKVR---MLKKTG---EVI--MGQKIHPTGFRLG--IT-QEHRSRWYA------DPK N--YPDTLQEDHKIRQYV--KATLA-----NAGISQIRVERKA-E-QIDLEVRTARPGVVVGRGGAGIDSLRVGLQKLIR INVVEVTK---VDTDAMLIGEYIAQQLEKRVSFRRVVRQAITRAQKA-GVEGIKIQVSGRVNGAEIARTEVTREGSVPL- -HTLRANIDYAYCTAKTIYGILGIKIWVFMAANDTISDMLTRIRNSCMAQHTTTKV-PATKMTRSIAKVLKDEGFIGEFE QEG----E---G----IKKYLVIFLKYK--GKNR-------Q---PIIRYLKRVSKPGLRVYKNRKELPRVLGGIGIAII STSSGIMTDREARKRGIGGEVLCYVWIQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATAIGPIPLPTKRRIYCLLRS PHVDKDSR-EHFETRTHRRIVDIYQPSSKTIDALMKLDLPAGVDIEVKLAKERVGVVVSNKMHKTIVVAIENRSAHPRYG KIVVKTKKYKVHDEE--NKCNEGDRVRIRETRPLSRTKRWELSEIIGSK------------------------------- -MSRSL-KKGPFIAD-HLLKKIEALNA---KNEKQ----VIKTWSRSSTIIPDMVGHTIAVHNGRQHVPVFISD-QMVGH KLGEFAPTRTYRGHG------S---DK----KSK------R- >DELTA_Anaeromyxobacter_dehalogenans_2CP-1 Concatenation of 2 sequences MALKEYKPTSPARRHMTVADFAE-ITKA------------KP-EKRLTKPVRKSGGRNAHGKVTTRH-IGGGHKRR---- YRLIDWR-R--DK-DGVPAKVAAIEYDPNRTARIALLHYL-DGEKRYILAPVGVAVGDTLLSGA-D-VD-IRPGNALPVR TIPLGTVIHNVETAPGSGAKMIRTAGSFGQLMAK--EGGYAQIRLPSGEVRKVLQDCKATIGQLGNVESSSVRVGKAGKS -RWL-----GIR-P-TVRGLAMNPVDHPHGGGEGKS-G--QGNPHPVSP---WGQKTKGLKTR-NNRR-TD-K-FIVTRR --------------------------------MST---G-LLAKKVGMTQIFT-PEGD---------CVPVTVLEAGPCT VVRRK----TAE----K--DGY--DAVVIGF-------GVVDELSK----------PEVGVFK----------------- ---AG-TPIFRHVKEIRV-----KDAKQLGDL-----KA---GD-VLTV--DKV-FKANQRIDVAGVTKGRGFTGVMKRW NMKGAARDSSTAHEHHRH-VGAIGQR-KTPG-KVWKGKHLPGHYGVDNVTIQNLTVVGIEAEQN---------------- ----------VLLVSGA-VPGHADGLLFVN-MAKFDVYD-LSKKKV-GELDLADAVF----AG-EV-NEHLFYEVVKAKL ASDRSGTHAVKNRSL--------VS-GGGKKPW---------KQKHTGRAR--------QGS---TR-AS----QW---- VGGGKAMGPK-P-RDYSYDVPKKVRKAALRSALALRSKDQ----------------K-LVIVQEW------KPA------ --PKTALVV---DDAN--L---ALAKSVRNLHGSD-F---------------LAVEGLNVYDILRHDA----LVLTADTA KKLEARLKERYDKQL----RAELMKELGFANPMQAPRLEKIVVNMGLG-EAINNGKIIDASVEQLAAITGQKPVVTRARK SIANFKLRQGQSIGAMVTLRGDRMYEFFDRLVSIALPRVRDFKGVSP-KAFDGKGNYTLGVREQIIFPEIN-----YDKV EKIKGLNITVVTT-----------------------ARNDEEGRALLRHLGMPFMSRVG-K--LPVKIPEKVKVS-V--- -D-G--N-VVKVEGPKGKMHFPT--NP-L--VSVQVDK-GE--VKV---AR-Q--DESHVAK-GLHGLTRTLVKNALEGV VKGYEKGLEINGVGF--KAEVKG-KE--IHFT--LGFSHPVVFKL-P-D-GVTAEVD--AKQTKLTIRS-VDKHLLGLTA AKVRALR------PPEPY---KGKGIKYADETIRRKEGK----------MIQQQTMLDVADNSGAKRVMCIKVLG-TRRK Y--ASIGDVIVVSIKEAIPQ-A-------KVKKGEVARAVIVRTAREVKRPDGSYIRFDGNSAVLIN-KDLE-PIGTRIF GPVARELR-ARKFMKIISLAPEVLMS-L--NQLKAPRGA-NRAKKRVG-RGQGSGL-GKTAGRGGKGQKARSGNM-H--- -FEGF-E-GGQMPLQRRLPK-FG--FHNVKVGDLVDPAALKSA-GLVRVV---------VLA--GGE-L-S-S-A-LTV- KVHRVTAGARATIEKAGGKV-K---MQK--GRM---RGKA-YRGSDLAQG----------EYGLQAT--ECGRLTSRQIE AARVAITRYV------KRGGKLWIRVFPDKPITKKPAETRMGTGK---------GNVEFYVAVIKP-GRVLYEL--AG-- VDDASAKKAFHLAAHKLPVATKM-VHVTTREKRRARIRRKI---SGTELRPRLTIYKSLKHMYAQLVDD---V--AGKTL VSVATT-SKSL-KGEL----GDE-DKTAAAKKVGEALAKA--AKAKG-IEQVVFDRNGFDYH--GRVEAVAAAAREAGLK F-------------------------------------------------------------APG-PHASLSYLRVAPRK VRIVADEVRGMKVGDALAMLKYT---------------------------------PQSAAKPLAKLLRSAVAN----A- EQGGGRVDVDALFVKTLTVDQGPKMRRFMARAMGRAFRVEKKTSHVYVELGTMAEIRKGDTVKVIAGK------EK-GKS GRVLEVLREDG--RVR--VEKLMTVKRHQK----KG-RSQANPE-GGILEMAGTIAISSVM-VVGKDE-----KPVR--R --EKIGREL---GA--------KEKAR---LQKRKT---AAK--MGQKVHPIGFRLG--VI-RSWDSKWYE------E-K N--YAKWLHEDIKLREFV--KEKLG-----QAGISRIEIERAA-N-KVKINVHTARPGIVIGKRGAGIETIKKDLQGLVY LNVVEVRK---AETDAQLVAENIATQLERRIAFRRAMKKSVQTALKF-GAKGIRVACSGRLGGSEMARYEWYREGRVPL- -HTLRADIDYGFAEAKTTYGKIGCKVWIMMSFTDPIGDMLTRIRNASSARHEKVLV-PASRLKVRIAEVLREEGFIKDFV LHE----D---G----VQGAITIVLKYS---ADR-------E---PAISDIKRVSKPGLRRYVATDSIPRVLNGMGVAIL STSKGVMVDREARKQKVGGELICTVWMATQKIRIRLKAYDYKLLDQSAGEIVETAKRTGAKVAGPIPLPTRINKFTVLRS PHVDKKSR-EQFEIRTHKRLLDILEPTPQTLDALMKLDLSAGVDVEIK-RKSRIGVVVSNKMTKTVVVKVERRVADPKYG KIVTKAEKYKAHDED--QACQIGDRVRIVETRPISKDKRWRVAETIEKA------------------------------- -MARSI-KKGPFADK-HLTKKVEDANK---GNKKS----VIKTWSRRSTILPDFVGHTFAVHNGRKFVPVFVTE-NMVGH KLGEFAPTRTFHGHS------A---EK----KAAAAPAPAKK >DELTA_Anaeromyxobacter_sp_Fw109-5 Concatenation of 2 sequences MALKQYKPTSPARRGMTVSDFAE-ITKS------------KP-EKKLTKPVRKSGGRNAHGHITTRH-IGGGHKRR---- YRVIDWR-R--DK-DGVPAKVAAIEYDPNRTARIALLNYA-DGEKRYILAPVGVNVGDTLVSGE-T-VD-IRPGNALPIK AIPLGTVIHNVEAQPGSGGKMIRSAGSFGQLMAK--EGLYAQIRMPSGEVRKVLQDCKATIGQLSNVENSTVRLGKAGKS -RYL-----GRR-P-TVRGLAMNPVDHPHGGGEGKS-G--QGNPHPVSP---WGQKTKGQKTR-NNRR-TD-K-FIVSRR --------------------------------MAT---G-LLAKKLGMTQIFT-AEGD---------CIPVTVLEAGPCT VVRRK----TAE----K--DGY--DAVVIGW-------GEVDELTK----------PEVGVFK----------------- ---AG-TPVFRHVKEIRV-----KDAKLLGEL-----KA---GD-VLTV--DKV-FKQDQRIDVAGVTKGRGFTGVMKRW NMHGAARDSSTTHEHHRH-VGAIGQR-KTPG-KVWKGKHLPGHYGVDNVTIQNLTIVGVEADKN---------------- ----------LLLVKGA-VPGHNDGLLFVN-MAKFDVYD-LDKKKV-GEIELADAVF----AG-EV-NEHLFYEVVKAKL ASDRSGTHAVKNRSL--------VS-GGGKKPW---------KQKHTGRAR--------QGS---TR-AS----QW---- VGGGKAMGPK-P-RDYSYDVPKKVRKAALRSALALRSQEQ----------------K-LVIVQEW------KPE------ --PKTSLVV---DAAN--A---ALARSVRNLDGSD-F---------------LAAEGLNVYDILKHDA----LVLTAETA KMLEARLRERYEKEI----RSELMKELGFANPMQAPKLEKIVVNMGLG-EAINNGKIIDASVEQLSAITGQKPVVTKARK SIANFKLRQGQSIGAMVTLRGDRMYEFFDRLVSIALPRVRDFKGVSP-KAFDGKGNYTLGVREQIIFPEIN-----YDKV EKIKGMNITVVTT-----------------------ARNDEEGRALLRHLGMPFMSRIG-K--LPVKIPEKVKVS-V--- -D-G--N-LVKVEGPKGKMSFPT--NP-R--VKVAVDK-GE--VQV---TR-P--DDSPESK-GLHGLTRTLVKNALDGV VKGYERGLEINGVGF--KAEVKG-KE--IHFA--LGFSHPVVFKL-P-E-GVTAEVD--AKQTKLTVKG-VDKHVLGLTA AKIRALR------PPEPY---KGKGIKYAEEIIRRKEGK----------MIQQQTMLDVADNSGAKKVQCIKVLG-SRRR Y--ASIGDVIVVSVKEAIPQ-A-------KVKKGEVARAVIVRTSREVKRPDGSYIRFDGNSAVLIN-KDLE-PIGTRIF GPVARELR-ARKFMKIISLAPEVLMS-L--SKLKAPKGA-NRERTRVG-RGQGSGL-GKTAGRGGKGQKARSGNM-H--- -FEGF-E-GGQMPLQRRLPK-FG--FKNVKVGDLVDPAALKGA-GLVRVV---------VLG--GGE-L-K-S-A-VTV- KVHRVTAGARAAIEKAGGTV-K---MMK--GRM---RGKA-YRGSDLNQG----------EYGLQAT--ECGWLTARQIE AARVAITRYV------KRGGKLWIRVFPDKPITKKPAETRMGTGK---------GNVEYYVAVVKP-GRVLYEL--AG-- VDDESAKKAFHLAAHKLPVATKL-VHVTPREKRRARIRRKI---SGTAARPRLTIYKSLKHMYAQLVDD---T--TGTTI VSIATN-AKAL-RDEV----KDD-DKTAAAKRVGEALAKA--AMAKG-IEAVVFDRNGFDYH--GRVEAVAAAAREAGLK F-------------------------------------------------------------APG-PHASLSFLRVAPRK VRLVADEVRGMPVGDALAVLKYT---------------------------------PQAAAKHLSKLIRSAVAN----A- EQKGGRVDVDVLVVKTLTVDQGPKMRRFMPRAMGRAFRIEKKTSHVYVELGTMPGIRKGDTVKIISGK------EK-GKQ GKVLELLPEKG--RVR--IEKLMLVKRHQK----KG-RSQATPE-GGIIEKEGTVAISNVM-VLVGDK-----PVRR--- --EKIKREL---GA--------KEKAR---ADRRKT---AK---MGQKVHPIGFRLG--VI-RSWDSKWYE------E-K N--YAKWLHEDIHLREYV--KEKLG-----QAGISRIEIERAA-N-KVKINVHTARPGIVIGKRGAGIETIKKELQGKVY LNVVEVRK---AETDAQLVAENIATQLERRIAFRRAMKKSVQTALKF-GAKGIRVACSGRLGGSEMARYEWYREGRVPL- -HTLRADIDYGFAEAKTTYGKIGCKVWIMMSFTDPIGDMLTRIRNASNARHEKVLV-PASRLKVRIAEVLRDEGFIKDFV RHE----D---G----PQGAITIVLKYS---GDR-------E---PAISDIKRVSKPGLRRYVPTDSIPRVLNGMGIAIL STSKGVMVDREARKQKVGGELICTVWMATQKIRIRLKAYDYKLLDQSAGEIVETAKRTGAKVAGPIPLPTRINKFTVLRS PHVDKKSR-EQFEIRTHKRLLDILEPTPQTLDALMKLDLSAGVDVEIK-RKSRIGVVVSNKMAKTVVVKVERRVADPKYG KIVKRAEKYKAHDEN--NACQIGDKVRIVETRPMSKDKRWRIAETLEKA------------------------------- -MARSI-KKGPFADK-HLTKKVEDANK---GNKKS----VIKTWSRRSTILPDFVGHTFAVHNGRKFVPVFVTE-NMVGH KLGEFAPTRTFHGHS------A---EK----KAA--AAPARK >DELTA_Anaeromyxobacter_sp_K Concatenation of 2 sequences MALKEYKPTSPARRHMTVADFAE-ITKA------------KP-EKRLTKPVRKSGGRNAHGKVTTRH-IGGGHKRR---- YRLIDWR-R--DK-DGVPAKVAAIEYDPNRTARIALLHYL-DGEKRYILAPVGVAVGDTLLSGA-D-VD-IRPGNALPVR TIPLGTVIHNVETAPGSGAKMIRTAGSFGQLMAK--EGGYAQIRLPSGEVRKVLQDCKATIGQLGNVESSSVRVGKAGKS -RWL-----GIR-P-TVRGLAMNPVDHPHGGGEGKS-G--QGNPHPVSP---WGQKTKGLKTR-NNRR-TD-K-FIVTRR --------------------------------MST---G-LLAKKVGMTQIFT-PEGD---------CVPVTVLEAGPCT VVRRK----TAE----K--DGY--DAVVIGF-------GVVDELSK----------PEVGVFK----------------- ---AG-TPIFRHVKEIRV-----KDAKQLGDL-----KA---GD-VLTV--DKV-FKANQRIDVAGVTKGRGFTGVMKRW NMKGAARDSSTAHEHHRH-VGAIGQR-KTPG-KVWKGKHLPGHYGVDNVTIQNLTVVGIEAEQN---------------- ----------VLLVSGA-VPGHADGLLFVN-MAKFDVYD-LSKKKV-GELDLADAVF----AG-EV-NEHLFYEVVKAKL ASDRSGTHAVKNRSL--------VS-GGGKKPW---------KQKHTGRAR--------QGS---TR-AS----QW---- VGGGKAMGPK-P-RDYSYDVPKKVRKAALRSALALRSKDQ----------------K-LVIVQEW----KPG-A------ --PKTALVV--DDAAN--L---ALAKSVRNLDGSD-F---------------LAVEGLNVYDILRHDA----LVLTADTA KKLEARLKERYDKQL----RAELMKELGFANPMQAPRLEKIVVNMGLG-EAINNGKIIDASVEQLAAITGQKPVVTRARK SIANFKLRQGQSIGAMVTLRGDRMYEFFDRLVSIALPRVRDFKGVSP-KAFDGKGNYTLGVREQIIFPEIN-----YDKV EKIKGLNITVVTT-----------------------ARNDEEGRALLRHLGMPFMSRVG-K--LPVKIPEKVKVS-V--- -D-G--N-VVKVEGPKGKMHFPT--NP-L--VSVQVDK-GE--VKV---AR-Q--DESHVAK-GLHGLTRTLVKNALEGV VKGYEKGLEINGVGF--KAEVKG-KD--IHFT--LGFSHPVVFKL-P-D-GVTAEVD--AKQTKLTIRS-VDKHLLGLTA AKVRALR------PPEPY---KGKGIKYADETIRRKEGK----------MIQQQTMLDVADNSGAKRVMCIKVLG-TRRK Y--ASIGDVIVVSIKEAIPQ-A-------KVKKGEVARAVIVRTAREVKRPDGSYIRFDGNSAVLIN-KDLE-PIGTRIF GPVARELR-ARKFMKIISLAPEVLMS-L--NQLKAPRGA-NRAKKRVG-RGQGSGL-GKTAGRGGKGQKARSGNM-H--- -FEGF-E-GGQMPLQRRLPK-FG--FHNVKVGDLVDPAALKSA-GLVRVV---------VLA--GGE-L-S-S-A-LTV- KVHRVTAGARATIEKAGGKV-K---MQK--GRM---RGKA-YRGSDLAQG----------EYGLQAT--ECGRLTSRQIE AARVAITRYV------KRGGKLWIRVFPDKPITKKPAETRMGTGK---------GNVEFYVAVIKP-GRVLYEL--AG-- VDDASAKKAFHLAAHKLPVATKM-VHVTTREKRRARIRRKI---SGTELRPRLTIYKSLKHMYAQLVDD---V--AGKTL VSVATT-SKSL-KGEL----GDE-DKTAAAKKVGEALAKA--AKAKG-IEQVVFDRNGFDYH--GRVEAVAAAAREAGLK F-------------------------------------------------------------APG-PHASLSYLRVAPRK VRIVADEVRGMKVGDALAMLKYT---------------------------------PQSAAKPLAKLLRSAVAN----A- EQGGGRVDVDALFVKTLTVDQGPKMRRFMARAMGRAFRVEKKTSHVYVELGTMAEIRKGDTVKVIAGK------EK-GKS GRVLEVLREDG--RVR--VEKLMTVKRHQK----KG-RSQANPE-GGILEMAGTIAISSVM-VVGKDE-----KPVR--R --EKIGREL---GA--------KEKAR---LQKRKA---AAK--MGQKVHPIGFRLG--VI-RSWDSKWYE------E-K N--YAKWLHEDIKLREFV--KEKLG-----QAGISRIEIERAA-N-KVKINVHTARPGIVIGKRGAGIETIKKDLQGLVY LNVVEVRK---AETDAQLVAENIATQLERRIAFRRAMKKSVQTALKF-GAKGIRVACSGRLGGSEMARYEWYREGRVPL- -HTLRADIDYGFAEAKTTYGKIGCKVWIMMSFTDPIGDMLTRIRNASSARHEKVLV-PASRLKVRIAEVLREEGFIKDFV LHE----D---G----VQGAITIVLKYS---ADR-------E---PAISDIKRVSKPGLRRYVATDSIPRVLNGMGVAIL STSKGVMVDREARKQKVGGELICTVWMATQKIRIRLKAYDYKLLDQSAGEIVETAKRTGAKVAGPIPLPTRINKFTVLRS PHVDKKSR-EQFEIRTHKRLLDILEPTPQTLDALMKLDLSAGVDVEIK-RKSRIGVVVSNKMTKTVVVKVERRVADPKYG KIVTKAEKYKAHDED--QACQIGDRVRIVETRPISKDKRWRVAETIEKA------------------------------- -MARSI-KKGPFADK-HLTKKVEDANK---GNKKS----VIKTWSRRSTILPDFVGHTFAVHNGRKFVPVFVTE-NMVGH KLGEFAPTRTFHGHS------A---EK----KAAAAPAPAKK >DELTA_Bdellovibrio_bacteriovorus_HD100 Concatenation of 2 sequences MGIKTFAPRSHGRRGMTGFDFKE-ITKT------------TP-EKSLLAPLKKQAARNNHGQITIRH-QGGGHKRK---- YRLVDFK-R--NK-LEVAAKVIAIEYDPNRTCRIALISYI-DGAKAYILAPVGLNVGDTVISSD-K-AD-IKPGNSLTLG AIPVGTVIHNIELRPGKGGQICRGAGASATLAGK--GDKYCQVRMPSGELKQVLTVCRASIGQVGNTDNENINLGKAGRS -RWR-----GIR-P-SVRGMHMNPVDHPLGGGEGVG----KGHH-PVTP---WGQPCKGFKTR-NNKRTNS---SIIKRR --------------------------------AGLKLNG-LFAFKEGMATIYN-ENGE---------AVPVTVLRYEPWF VSQIK----TNE----A--DGY--EAIQVAC-------HP--KSNK----------AEKGHLK----------------- ---AGFENGAQFVKELRQ--------AAPEGT-----VV---GA-QISI--D-S-LAKGDFVKITSKSKGKGFAGSVKRW GFAG-GPASHGS-KFHRR-PGSSGNR-TWPG-RVMPGKKFPGHLGAETVTVKNVEVVQIIAEEN---------------- ----------VLMVKGP-VPGARNTLVKLV-MATVNVLN-WKKEKV-GSVELAADVF----ET-PV-KKEVLHTVVQWQL AARRQGTHMTKTKGL--------VS-GGGKKPF---------KQKGTGGAR--------QGS---SR-SI----LM---- PGGGTAFGPQ-P-RSYAFVLPKKVRRLGLSMALSHLQKEG----------------K-LFIVDSM----ASE-------- --GKTAVLV--DSVVD--D---KFNRASKNLPTFK-Y---------------FPVEGLNVFDLLKYDA----AVITKDSV AKIVNRLHTRYNKEI----APALKNQLGVKNVMQVPRLEKITLSVCLS-EAVQNPKILNTVVDEITAITGQKAVITKAKK AISNFKLRAGIPLGVRVTLRREKMWSFMDRLNTLALPRVRDFRGLPN-KGFDGRGNYNMGLKEQIVFPEIN-----YDKV DKTRGMNITICTT-----------------------AKNDTEGRALLEALGMPFMSRIG-K--APVIFDNTVQVS-V--- -S-P-AN-EVVVKGAKSSLTIGM--KP-N--VSAKIDG-NK--VVL----T-P--NDDKESR-AMHGLYRALIQNAVTGV TKGFSRGLELQGVGY--RANVAG-KK--LELS--LGFSHPVIFDI-P-E-GIEIKVE--K-QTSLTVNG-PSKELVGQVA AKIRSFR------PPEPY---LGKGVRYAGEQIRRKAGK----------MIQMQTRLNVADNSGAKEVMCVKVLG-SKRR V--ASIGDVIVVSIKEALPN-A-------KVKKGDVAKAVVVRTVAKLRRPDGSYIRFDDNSAVLIN-ASKE-PIGTRIF GPVARELR-AKSFVKIVSLAPEVLSL-L--KTLAPKAGS-KHAPKRIG-RGIGSGM-GGTATKGHKGQLARTGGT-V--- -RRGF-E-GGQTPLHRRLPK-FG--FSNVNVGQLVTPESLHAA-GLISVK---------ILG--NGE-L-K-T-A-LTV- KAHKFSESAKKAIEAAGGKV-K---QFV--GRA---TGFA-VRGANLDFG----------DYGLQAV--EEGRLTARQLE AGRIAISRSV------KRGGKIWCRVFPNIPVTKKPAETRMGSGK---------GNPELWVARVLP-GKVLFEM--NG-- VTREQAKEAFERAAHKLPFKTRF-LRKVNRLKKKIRIRKTV---KGTAERPRLCVFRSGKHVYAQIIND---V--DGNTL VAVSSL-GKED---------KSG---IDMAKLVGMEAAKA--ATAKN-IKDVVFDRNGYLYH--GRVKSLADGAREGGLN F--------------------------------------------------------------ME-VKASLKYARVGAQK ARLVADLVRGKDVNEAVKTLTFL---------------------------------NKKTAGMVKKLIESAVAN----A- EYKK-VMDVDSLYVKAIWVDQGPVLKRFRPRAQGRAFGVRKKTSHINVVLEEKLKIKKGATVQVITGS------DK-GKK GTVIAVDANAM--KIQ--VQGVKVQTHYDK-----------K---DGLLKKEGFIDYSNVK-LVEAAS-------KE--- --KKTSKKA---------------------TKSKSA--------MGQKVNPIGLRVG--VI-RTWDSRWYA------KGQ Q--YYENLHEDIRLRKFL--KDKLK-----NAGVAKIEMERAA-K-KIKIIISTARPGVVIGKKGSGIDALKAEVQKLVF LSIQEVRK---PDLDAQLVAESIAQQLEKRISWRRALKKSIAAAIKG-GVRGIKIRVSGRLDGAEIARSEWYNEKSVPL- -HTLRADIDYGTAESLTAYGIIGLKVWIY---MDTISQFLTMIRNAGAAKHEKVDM-PASKVRAGIAQILVNEGFIRSFK VAK----D---S----KQGIMRVYLKYD---EAG-------G---HAINNIDRVSRPGRRVYVKSDKIPTVRSGMGMSII STSKGIMSGKQATEQKLGGELLATLWMQSQKIRIRLKAFDHKLLDQSTKEIVETARRTGAKVAGPIPLPTRINRYTVLRS PHVDKKSR-EQFEVRTHKRMLDILEPTQQTVDQLMKLDLSAGVDVEIKLKIEVVGEVISDKMDKTISVLIYRMVKHAKYG KYVKKTSVFKAHDEK--NQAKIGDIVKIRETRPLSKTKRWALAEVVETA------------------------------- -MARSI-KKGPFVDT-HVQKKIDNALE---KNDKK----VIKTWSRRSTILPETIGLTFAVHNGRKFVPVYITE-NMIGH KLGEFAPTRTFHGHA----------EK----KAA--APAAKK >DELTA_Desulfatibacillum_alkenivorans_AK-01 Concatenation of 2 sequences MAVRKTKPTSPGRRFQEFGTFEE-ITKK------------KP-EKSLIKVVKKSGGRNANGRVTCRH-RGGGSRRQ---- LRIVDFK-R--NK-TGIPAKVAAIEYDPNRGARLALLHYV-DGEKRYIIAPVNLTVGDMVESGP-E-AD-IKPGNALPLN NIPLGTQIHNIELKVGKGGQVVRGAGTFAQLVAK--EGKYAQVRLPSGEVRLVLLKCMATIGQVGNVEHENLALGKAGRK -RWL-----GRR-P-SVRGVAMNPVDHPMGGGEGRS-S--GGRH-PCSP---WGMPTKGYKTR-KNKT-TD-K-FIVRKR --------------------------------MSK---G-ILGKKLGMTGLFS-SDGR---------HIPVTVIEAGPCV VTQIK----TKD----K--DGY--NALQLGF-------GP--KTNK----------PETGHFK----------------- ---SG-GAAYVMVKEFAV--------DNPEEF-----EL---GQ-SLST--E-L-FAVGEKIDVAGVSKGRGFAGVMKRH GFGG-GRMTHGG-RCKRR-PGSIGCS-AWPS-KVIKGKKLPGHYGVERKTVRNLEIVDIRADQN---------------- ----------LILLKGA-VPGAKSGMLELK-MAKVEVCN-MSGEKV-SEIDLADEIF----GV-EV-KGSVLHEVVVMQL ANRRAGTVCVKNRSD--------VR-GSTRKLY---------RQKGTGRAR--------KGD---IK-SP----VL---- RGGGVVFGPH-P-RDYSYKVPKKVRKAALKMALSSKLADN----------------S-LKVVDNM----DLP-E------ --IKTKLIV--TTGEE--K---NLELSARNVKGVK-V---------------MPTAGLNVYDILKYGN----LILAQGAI EAIESTLRTEYLENV----APKLQEEFGYSNAMQIPRLSKVVLNMGLG-EAIQNNKILEGAVDELTLISGQKPVVTKAKK SIAAFKLREGMPIGVTATLRRDRMYDFLNKLVNVTLPRVRDFRGISP-KAFDGRGNYTLGIREQIIFPEIN-----YDRI DKVKGLNITIVTT-----------------------AKNDEEGRRLLTLLGMPFMSRVG-K--KPIPIPAKTKVT-V--- -SNG----TVTVQGEKGKLERPL--HP-D--VELKIEG-DE--ITV----V-P-VVERRKIT-AVQGLVRSLVANMVTGV STGFKRVLEVNGIGY--KAELNG-QT--LNLT--LGFSHPVDFPL-P-Q-GITAEVD--KKN-NITLEG-IDNELLGQTA ASIRALR------PPEPY---KGKGIKYAEERIIRKAGK----------MIQAETRLTVADNSGAKVLGCIKVLG-SKRR Y--ASVGDIIVVSVKEAIPN-S-------KVKKGDVMKAVIVRTKKEIRRPDGTYIRFDDNSAVLIN-ATKE-PIGTRIF GPVARELR-AKRFMKIISLAPEVLMK-L--NELSPPKGA-RTARKRKG-RGPGSGL-GKTAGKGHKGQKARSGGG-V--- -RPGF-E-GGQMPVHRRLPK-RG--FCNVNVRDLVDAAALREA-RLISVK---------ILG--HGE-I-T-Q-A-LTV- KADQWSESAKEKIEKAGGKI-K---VQK--GRM---QGVA-RRGGVLNFG----------QFGLQAL--ECGFVTNRQIE AARIAMTRHV------KRGGKIWIRIFPDKPFTKKPAEVRMGKGK---------GAPEGWVAVIKP-GRILYEM--DG-- VSYELAAEALRLAAHKLPIKTKI-VKNRTHEKRKVRVRKKL---FGTQDRPRLSVFRSAKHIYAQVIID---E--TGQTI AGASTL-DKEA-KDKG----GFE-SKVEAAKFVGKLVAQR--AKEKG-VTKVVFDRNGFLYH--GRVKAVSTGARDGGLE F--------------------------------------------------------------MQ-VKATAKYMRVSPQK VRKVADAVKGKPVEAGLNVLQFM---------------------------------PQKSAAMIAKVIRSAVAN----A- EVG--GVDVDDLVIKGVIADQGPTLKRFRARAQGRGARILKRTSHITVVLEQACPIKKGDRVKVIAGR------EK-GKV GNVLRVLADKE--KVI--VENLNMVKRHQK----PG--GM-TKQ-GGIIDMEAPLHWSNVM-VMCEKC-------VA--P --VRAANRV---LE--------DGKVR---VCPKCN---EPL--MGQKVNPIGLRLG--IV-KTWDSRWYA----E-K-G K--YAEFIREDFKLRKFL--KKKLH-----HAGISKIEIERSG-R-RVRLRVFAARPGIVIGKKGSEIEQLKKELEKMVL IDIQEVRK---PELDAQLVAENVAMQLERRVAFRRAMKRGISSAMRF-GAQGVKIMAAGRLGGAEMARREWYREGRMPL- -HTLRADIDYGYTEANTTYGVIGVKVFIFMGMTDPLADMLTRIRNGVKARFTQVDI-PASNVKIDVARVLKDEGFIKNYK VIK----D---D----KQGILRVYLKYG---PSQ-------T---PVIYGIERVSRPGRRVYLKAKDVKPVLHGMGSAIL TTSQGVMTDREARIKNVGGEVICKVWLMNDKIRIRLKAYDHKLLDQSAADIVDTARRTGAKVVGPIPLPTRINKYCVLRS PHVDKKSR-EQFEVRTHKRLLDILEPTQQTVDALMKLDLSPGVDVEIKV---MVGTVVSDRMDKTVVVLIERTVKHPLYK KYIKRRARYSAHDES--NSCGMGDLVQIAESRPLSKTKRWRVTQILEKA------------------------------- -MPRSL-KKGPYIEP-KLLNKVMVAQE---SRSKR----VIRTWSRRSTIIPEMVGLTLAVHNGKKFLPVFVTE-NMVGH KLGEFSPTRTFYGHA------G---DK----KTR------GK >DELTA_Desulfobacterium_autotrophicum_HRM2,_DSM_3382 Concatenation of 2 sequences MSILKTKPTSPGRRAQEYHSFEE-ITKT------------QP-EKGLLSRLKKTGGRNVNGRITSRH-KGGGAKRH---- YRIIDFK-R--DK-DGIPAKVSSIEYDPNRSARIALLVYA-DGEKRYILAPREINVGDLIETGP-E-AD-IKPGNCLPLE NIPLGTRIHNIELKVEKGGQVVRSAGAFARLMAK--EGKYAQVLLPSGEVRMIHLKCKATIGRIGNEKHGDLKLGKAGRA -RWL-----GRR-P-SVRGVAMNPVDHPMGGGEGRS-S--GGRH-PCSP---WGTPAKGYRTR-TNKK-SD-Q-YIIKRR --------------------------------MFK---G-MLGKKIGMTSIFA-ADGT---------LVPVTVVRFGPCV VTQVK----AEK----T--DGY--NALQLGF-------DE--RCNK----------PKVGHFK----------------- ---SG-STGFNVVREFRV--------ENTDEF-----EV---GQ-NIGL--D-G-FAIGDKVNVSGTSKGRGFAGTIKRH GFSR-GPETHGC-RNHRK-PGSIGCS-AWPA-RVVKGRRMPGHMGVDRKTVKNLEIIDIRPDEN---------------- ----------LVMIKGP-VPGWKTGLLEIR-MAAVDVLN-RSGEKV-SEAFLADEVF----SI-PV-KKSVLHDVVRMQL ARRRSGTAKSKGRSE--------VS-GSTRKLY---------RQKGTGNAR--------SGS---VK-SP----LR---- RGGGVIFGPA-P-RSYAYAIPKKVRALALKMALSSKLAAN----------------E-LSVIDTF----AMD-S------ --IKTKLIV--IDGDD--R---NLVLSARNIPDVK-V---------------IRTEGLNVYDILKYDN----LLLIESAI KEIETTLKEMYEKEI----VPGLKETFGYKNPMEVPKLDKIVLNIGLG-EAINNVKLLDSAVEDLALIAGQRPVITKAKK SIAAFKLREGMPIGCMVTLRREKMYDFLLKLINITLPRVRDFRGISG-KAFDGHGNYSLGIKEHIIFPEID-----FDQT DSIKGLNVSIVTT-----------------------AKTDKEGKELLKQFGMPFMSRIG-K--KPVQIPEKVEVS-V--- -K-G-D--LISIKGPKGSLDRSL--HP-A--VKLAIEN-GM--VNV---SVTD--DQDRKTV-ALQGLFRSLVANMITGV SVGYEKKLLLNGIGY--RAEVNG-NT--VVLN--VGYSNPVNFEL-P-K-GISALVE--K-NTTLSLSG-IDKEIVGETA ARIRRIR------PPEPY---KGKGIMYSDERIIKKAGK----------MIQTETRLTVADNSGAKELYCIKVLG-SKRR Y--AGIGDVIVVSVKEAIPN-A-------KVKKGDVVKAVIVRTKKEVSRPDGSMIRFDDNSAVIIN-ASNE-PIGTRIF GPVARELR-AKRFMKIISLAPEVLMK-L--HELSPSEGS-RKKRKRVG-RGPGSGM-GGTSTRGNKGHNQRSGGG-T--- -RPGF-E-GGQMPLHRRLPK-RG--FKNVNLSDLIDVAALKQT-GLIKVK---------ILG--DGE-V-S-K-A-FTF- KQCLVSKTARQKIEAAGGSI-K---RMR--GRL---KGKP-TGGTDLTFG----------DFGLQAT--ECGYINARQIE AARIALTRKI------KRTGKTWIRFFPDKPVTKKPAEVRMGKGK---------GPTDAWVAAIRP-GRILYEM--EG-- VPRELAKEALRLAAHKLSVKTRF-VRLVSRLKRQKRIRKRI---TGTGERPRLCVFRSSAHIYAQVIDD---V--TGSTL AAASTL-DKEF-IENK----DKL-VGKDAATAIGRLVGAR--ALEKG-ISKVVFDRNGFLYH--GRVKALSDGAREAGLN F--------------------------------------------------------------ME-VKSVTKYVRISPQK LRGPVDVIKGQKVEDALNLLKFM---------------------------------PLKAAEIIAKALSSAVAN----A- EHNH-EMDVDDLRVKNIIVDQGPTLKRFRARARGRGARILKRSSHLTVIVDAKLKIKKEDKVKVLTGK------DK-GKI GKVLKVLRKKN--RAV--VENINVAKIHQR----PT--QA-NPQ-GGIVDKPMPVDCSNLM-IMCNSC-------IK--P --VRVGIKQ---LE--------DGKVR---ICKSCN---EQI--MGQKVNPIGLRLN--IV-KTWDSRWYA------D-K N--YADFVFEDYKLRAFL--KKKLF-----HAGISKIEIERFT-K-RIRIRVFAARPGIIIGKKGSEIALLKKEIEQMVL IDIQEIRR---PEIDAQLVAENISAQLERRIAFRRAMKRSVSSAMRF-GAQGIKIICSGRLGGAEMARTEWYKEGRIPL- -HTLRADVDYGFTEAKTTYGAIGIKTFIFMAMSDPVADMLTRIRNGAKAEFAKVDI-PGSKLKLELARVLKEQGYIKNYK FVE----D---D----KQGILRVYLKYV---ADK-----------PVIYGLERVSKPGRRMYTKSKEIKSVLNGLGISIL STSKGLMTDKQAKKENVGGEVLCNIWMIKTKIRIRLKAYDHKLLDQSSIDIVDTARKTGAKVVGPIPLPTRINKFCVLRS PHVNKKSR-EQFEIRTHKRLMDILEPTQQTVDALMKLDLSPGVDVEIKLKRVLLGTVVSNKMDKSVVVEVERLVQHRVYK KYITSHKKYAAHDET--QLCQIGDMVKITESRPLSKTKRFRVSEIVKKA------------------------------- -MPRSL-KKGPYIAQ-ELLNKVLVAQE---TRSKK----VIKTWSRRSTIFPDMVGLTLAVHNGKKFVPVFVTE-NMVGH KLGEFSPTRTFYGHA------G---DK----KAK------MR >DELTA_Desulfococcus_oleovorans_Hxd3 Concatenation of 2 sequences MGIRKVKPTSPGRRFQEYSTFEE-ITAD------------RPSEKGLIEPLRKTGGRNVNGRITCRH-RGGGHKRH---- YRVIDFK-R--NK-DDIPAKVAAIEYDPNRSARIALLFYA-DGEKRYILAPVNLKVGDTVMSGQ-A-SE-IKPGNAMPLA SIPLGTEVHNIELRLGKGGQIVRSAGGYAKVMAK--EARYVLLRLPSSEMRKVLATCKATIGRVGNVEHDDVSIGKAGRN -RWL-----GKR-P-RVRGVAMNPVDHPMGGGEGKS-S--GGRH-PCSP---WGQQSKGVRTR-NNKR-TD-Q-FIVKRR --------------------------------MCR---G-IIGRKIGMTGVFS-DQGE---------YVPVTVIEAGPCV VTQIK----TVE----T--DGY--SALQLGF-------LE--KINK----------PLAGHFK----------------- ---SG-GVGFAYVREMAV--------DDPSAY-----TL---GQ-VINA--E-L-FSAGEKVHVAGLMKGRGFAGVVKRH GFAG-GKDTHGC-HSHRV-PGSIGTS-AWPS-KVFKGRKLPGRYGNTRITTKNLKIFDIQPETN---------------- ----------LILIKGA-VPGSNNGLVEIR-MAVVDIKN-MNGETV-SQAELPDSIF----DV-EV-KSSVLHEVVKMQL ARRRSGTASTKGRSD--------VA-GSRAKLF---------RQKGTGRAR--------RGD---VK-SP----LL---- KGGGVVFGPH-P-RSFDYSVPKKVRKLALKMALTSKLRDN----------------T-LTVVDQF----RFD-R------ --IKTKLVI---SDGS--E---TLEKSARNVPKVK-V---------------LKCEGLNVYDILKYKN----LVLPEAAI KMIESSFKEFYTTEV----VPKLQETFGYKNVMQIPKLEKIVLNMGLG-EAISNIKIIDSAVEELKLISGQQPVIRRARK SIAAFKLRQGMPVGCMVTLRHERMYDFFNKLVNIALPRVRDFRGISG-QAFDGQGNYTLGVREQIIFPEIE-----YDKI DKIKGLNITIVTS-----------------------VQKDDEARELLRLMGMPFMARIG-K--KPIQVPDKVKVS-Y--- -T-D--R-CITVSSDKGVLSRTV--QG-D--VDLEIKE-DH--IHV------VAGSENRKVL-ALQGLYRSLVNNMVQGV STGFSRSLEINGIGY--RVELNG-QT--VVLN--IGYSHPINFEL-P-D-GVTAKVE--K-N-VLTLAS-IDKELLGQTA ASIRKLR------PPEPY---KGRGIKYTDEHIQRKAGK----------MIQTETRLKVADNSGAKIVYCIKVLG-SRRR Y--ATVGDVIVVSVKEAIPN-S-------KVKKGDVLKAVIVRTKKEIKRPDGSYIRFDENSAVLIS-GNNE-PLGTRIF GPVARELR-AKRFMKIVSLAPEVLMD-L--SNLSPAPGS-TKARKRLG-RGPGSGN-GTTAGRGNKGHNSRSGGG-V--- -RPGF-E-GGQMPLHRRLPK-RG--FVNVNIRDLVDGEALKAK-GLVKIK---------LLG--KGD-I-A-Y-P-LTV- KVSHVSRSAREKIEAAGGAI-K---QQR--GRR---TGTR-LAGSTLSFG----------EFGLQAT--ECGMITARQIE AARIAMTRYI------KRAGKTWIRIFPDKPFTKKPAEVRMGKGK---------GAPEGWAAVIRP-GRILYEM--DG-- VPDELAREAFRLAAHKLPVKTKF-VKQELRLKRKARIRKKI---AGTPERPRLSIFRSARHIYAQLIDD---T--KGVTF VTASSN-EPDV-KNNT--ELSGK-NKSEVAVFVGKLIAGR--AKDKG-ISSVVFDRGGFVYH--GRVKAVSDGAREGGLN F-------------------------------------------------------------MEQ-VSATARYLRIGPQK VRMLVDGIKGKSVEKGLNTLRFM---------------------------------PNKGAGLVEKALRSAVAN----A- EEK--NMDVDGLVILNVLVDQGPTLKRFRPRARGRATRILKRTSHITVVLAEKVNIKKNDKVKVVAGK------DK-GKI GKVLSVNREKN--RLV--VENINMIKRHTR----PN--VS-NRQ-GGIIEREAPIDRSNVM-LMCGKC-------VT--P --VRIKMKE---LE--------DGKVR---MCGKCK---ELI--MGQKVNPEGLRLG--IV-KTWQSRWYA------D-K E--YADFILEDFKLREFV--KKKLH-----HAGIAKVEIERSL-N-RIRLRIFAARPGIVIGKKGNEIEQLKNEIRQKLA IDIQEVKK---PETVAQLVAENVAGQLERRVAFRRAMKRGVSSAMRF-GVKGIKIICSGRLGGAEMARREWYREGRVPL- -HTLRADVDYGFVEASTTYGRIGVKVFIFMKVTDPIADMLTRIRNAGKAKHASVDM-PNSKLKTRIADILKASGYVKNYK VID----D---D----LQGVLRVYLKYD---KHN-------T---HAIYGIERVSKSGRRVYTKNKDMAPVLNGLGISIL STSRGVMTDKQAIKENVGGEVLCNVW-MNTKIRIKLKAYDHKLLDQSALDIVDTARKTGARIVGPIPLPTRINKFCVLRS PHVDKKSR-EQFEMRTHKRLLDIIEPTQQTVDALMKLDLSPGVDVAIKLKRQFEGTVVSDKMDKTVIVAVERLVKHQEYK KYVRRTAKFAAHDEQ--NQCAVGDKVIITESRPLSRTKHWRVVNVVEKA------------------------------- -MPRSL-KKGPFVDE-KLENKIVIARN---TKSSH----IIKTWSRRSTVTPEMVGLTFAVHNGKKFIPVFVTE-NMVGH KLGEFSPTRTFYGHA------G---SK----KSK------VR >DELTA_Desulfotalea_psychrophila_LSv54 Concatenation of 2 sequences MAIKTYKPTSPGKRHQVSIKNAN-LAKK------------GP-EKSLVTSLSKTGGRNNYGRITSRH-IGGGHKRK---- YRIIDFK-R--NK-MDIDAKVVAIEYDPNRSANIALLSYI-DGEKRYILSPEGVSVGDKIVAGD-N-VD-IQPGNCLPLA NIPLGTIIHNIEMKIGKGAQIVRSAGTSAQLMAK--EGDYVLVRLPSGEVRKFHRLCRACVGQVGNREYESQKLGKAGRS -RWL-----GKR-P-HVRGVAMNPVDHPMGGGEGKS-S--GGRH-PCTP---WGMPTKGYKTR-TNKS-SD-K-YIVKKR --------------------------------KTM---G-ILGKNIGMTRVYG-EVGQ---------AIPVTVVQAGPCK VLQVK----TNA----T--DGY--NAVQVGF-------EN--KVNK----------AEAGHFK----------------- ---SD-SEGFYFVREFRV--------VDPATY-----NV---GD-MISV--DAL-FKAGDIVDVQGTSKGRGFQGVIKRW GFKG-GPGGHGS-KHHRA-PGSIGCS-AYPG-RVVKGKKMPGRMGNDTVLKKNVTVVDVRIDEN---------------- ----------VVLLKGP-MPGAKNGLLKIYIMSTVSVVN-TNNEKV-DEIELNDAIF----NR-EV-KEYILHDVVRMQR AAKRAGTASTKTRVE--------VR-GGGAKPW---------RQKGTGRAR--------AGS---RT-SP----LW---- RGGGVTFGPK-P-RDYSFKLNRKVRQQAVSMALSARFQEG----------------N-LIVLDNF----IMD-A------ --IKTKLIV--MDDAS--E---NLSKSCRNVHGYR-I---------------LPAEGLNVYDILLHKK----VVLVKPVI ESLESALKEYYTNEC----VPALKDQLGYTNPMQIPKIEKIVLNMGLG-EAVQNPKIVEGAAEELTKIAGQRAVVTKAKK SIATFKLREGMPIGCRVTLRGEKMYDFLSKLVNIALPRVRDFRGVSP-KGFDGRGNYSMGIQEQIIFPEID-----YDKI DKIKGFNITIVTS-----------------------AKTNDEGRSLLRLMGMPF-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MIQTETVLNVADNSGAKKVLCIRVLG-SRKR Y--ASIGDVIVVTVKEAIPH-A-------KVKKGDVMKAVVVRTAKENRRPDDTWVKFDENAAVMLG-ASGE-PVGTRIF GPVARELR-NQGFMKIISLAPEVLLT-L--GNLSPQEGS-TKQRKRLG-RGPGSGH-GKTAGRGHKGFKSRSGSG-I--- -KPGF-E-GGQMPLQRRLPK-RG--FTNVALSQLVSPAELVEA-GMVKIK---------ILA--NGE-I-T-K-A-VTV- KVDKISSQAKAQIEAAGGTV-K---VFK--GRM---RGAA-HRGSSLAFG----------DYALKAL--SCGTMTARQIE AARITINRTM------KRGGQVWIRVFPDKPLTKKPAETRMGKGK---------GSPESWVAIVKP-GRLLYEV--AG-- VSEDVAIKALSLASNKLPFPCKV-VKTLARAKRISRIRKKI---SGTSERPRLRVFKSNKHIYAQIIDD---A--SGKSL VAMSTV-DKQFDLG------DES-GKTAAAKKVGVVLAER--ATAAG-IKKVIFDRGGYIYH--GRVKSLSEGAREGGLD F--------------------------------------------------------------ME-ARAVGKYIRISPQK ARLVADVVRGMGVDQAITTLRFM---------------------------------PKKGAVILQKVIESALAN----A- TQDD-QADVDNLYVKVITIDGGPSLKRIRPRAMGRATGIIKRTSHITVVLDERTYLKTNDQVEVIAGK------DK-GRV GKVLRVLVDKD--KAV--VERANMIKRHTK----AT--EM-NQQ-GQIVEKEAPIHVSNLQ-LICPEC-------TK--T --GRVGKKV---LE--------DGKVR---YCKSCG---ESV--MGQKVNPLGIRLN--IT-RTWDSVWYA------D-K D--YSTFLIEDQKIRKFL--KKRLS-----HAGLSSVKIERTG-E-QVRIKLFTARPGIVIGKKGAEIEILKRELEKLVT LDIQEVRR---PEADAQLVADNIAQQLARRVAFRRAMKKAVSSALRF-GVQGIKIACSGRLGGAEMSRCEWVREGRVPL- -HTLRADVDYALSESHTTYGIIGVKVWIFMSMSDPLADMLTRIRNAVMVKFDTVEM-PSSTMKVSVAKVLKDEGYITDYQ IKE----D---G----VQNTLSINLKYG-----------------PD--------------------------------- ------------------GEAVITEYIPTEKIRIRLKAYDHKLLDQSTSEIVETARRTGSAVVGPIPLPTSINKFCVLRS PHVNKKSR-EQFEMRTHRRLLDILEPTQQTIDLLMKLELSAGVDVEIKLRKTRTGSVVSDRMEKSVVVRVERKVRHKLYG KFMKTSVKYLADDPE--NQCNIGDVVLIEECRPLSKRKRWRVKTILEQA------------------------------- -MSRSI-KKGPFIDD-HLQKKVDQSLE---SGSRK----VIKTWSRRSDISPEMVGLTFAVHNGKKFIPVFVSE-NMVGH KLGEFSPTRTYYGHS------A---DK----KGK------R- >DELTA_Desulfovibrio_desulfuricans_desulfuricans_ATCC_27774 Concatenation of 2 sequences MAVRKLKPTSAGRRFQTVSDFEE-ITRT------------RP-EKSLTVGLTKKSGRNNLGRITSRR-RGGGVKRL---- YRIIDFK-R--DK-TGIEARVAHIEYDPNRTARIALLHYT-DGEKRYILAPVGLKQGDVVMSGE-V-AD-IMPGNALPMQ RIPVGTVIHNIELYPGKGGQLCRAAGTYAQLVAK--EGKYALLRLPSGEVRKVLVTCVATVGQVGNVHHESIRLGKAGRN -RWL-----GRR-P-KVRGVAMNPIDHPLGGGEGRS-S--GGRH-PVSP---WGMPAKGYKTR-DKKKASS-R-LIVKRR --------------------------------EKM---G-ILGRKLGMTRIFD-GNGA---------AVPVTVIEAGPCP VTQVK----TAD----S--DGY--NAVQIAM-------TN--AVSK----------AMQGHFK----------------- ---AG-KGLFRHLREIRL--------TAAPEQ-----EL---GQ-ELTV--E-M-FAAGDTVKVTGKSVGKGYQGRMRRW NFAG-SKDSHGCEKVHRN-NGSIGNN-TFPG-RVFKGRKMAGHWGNETVTEMGLTIVDVRPEDN---------------- ----------VILVKGS-VPGPKNGLVLIR-MATVKVYD-QNKQES-GEVTLASDVF----EI-EV-RPEILNLVARAQM AAKRAGTHNVKTRAF--------VS-GGGAKPW---------KQKGTGRAR--------AGS---NR-SP----IW---- RGGAITFGPS-P-RDYTFKVNSKVRSLALKMALSSRLAAE----------------S-LMVVKGI----VLP-E------ --AKTKLIV--APEEN--A---DLTRSARNIPGLT-L---------------TTVDRLSVLEILKHKQ----LVLLEGAV ESVQTRLEKIYREKV----VPVMQKEFSYSSSMQLPGIEKISLNIGLG-AASQNNKLMEEAVAELSAIAGQKAVVTRAKK SIAAFKLREGMPIGARVTLRRDRMWDFLDKLMNFALPRVRDFRGIPD-RGFDGRGNFTLGIKEHTIFPELE-----VDRV ENPKGMNITIVTT-----------------------AATDKEGKFLLDQLGMPFMSRIG-K--LPIPVPNGVEVK-I--- ---G--TDVVEVKGPKGSLSTPV--CS-L--LQYEQAD-GH--VVL------TRIEDDRVTR-AQHGLRRSLLSNCIDGV TKGFSKALEVIGVGY--RVAVKG-NI--IELQ--VGYSHPVLVEL-P-E-GLKATVE--G-Q-VLTISG-IDKELVGEMA ARIRRIR------KPEPY---KGKGIKYATETIRRKVGK----------MIQVESTLQVADNSGAKKVACIKVLG-SHRR Y--ASVGDIVVVSVKEAIPH-S-------KVKKGDVMKAVIVRTAKEVRRMDGSYIKFDGNAAVLLS-TQGE-PIGTRIF GPVARELR-AMNFMKIISLAPEVLMQ-L--HNLYPFPEE-RKTRRRVG-RGSGSGL-GCTAGKGHKGQNARAGGG-V--- -APGF-E-GGQMPLQRRLPK-HG--FKNINLDRLITLDDIYAR-GLARVK---------ILS--RGE-V-K-S-A-LKV- EAHKFSQTAAEKIRGAGGEV-K---WQK--GRL---RGLA-TRGATVAFG----------DIGLKAV--QHGQLTSQQIE AARIAMMRHI------KRGGKVWIRVFPDRPVTAKPLETRQGSGK---------GAPVGWCAPVKP-GRVLYEI--KG-- VSLDLAREALTRAAHKLPVKTVI-VKNESRQRRKIRISKKV---SGTAERPRLVVYRSNLHVYAQIVND---L--DGATL VATSTL---ALGKNES----GLH-CNKGGAEKVGIEIARM--AKEKN-IDKVVFDRNGYLYH--GRVKAVADGAREGGLE F--------------------------------------------------------------ME-SKAIAKFQRVSPRK TRLVAKNVQGLGVEEAMNLLRFT---------------------------------PNKPAGVLYGVLKSALAN----A- SQLG-GVDVDAMVVKEVVVNEGPTWKRFMPRAQGRATKINKRTSHITVILAEMYRIRKDDKVMVIAGK------DA-GKI GKVLKILRKKD--RVL--VEKTNMVKRHMR----PN--PY-AQQPGGIVEKEMPIHVSNVM-VVCSAC-------GK--A --TRVGYKT---IE-----SEGKEKVR---FCKKCN---EVM--MGQKVHPFGFRLG--YN-KNWQSRWFS------K-K E--YPAFVYEDSKIRAFV--KKLLY-----HAGLSKIEIERAG-G-KVRLILSTARPGIVIGRKGVEIEKLRNDLRQKFS LEVNEIRR---PEVDAQLVAENIAQQLERRVAFRRAMKRTVSMARKF-GGEGIKVTCSGRLAGAEIARTEWYRDGRVPL- -QTLRADIDYGFAEARTTYGIIGVKVWIY-MLTDPIADMLTRIRNAHLALHKEVNV-PRSRMKESLAAILKQEGYVEDVA VAD---------------SNITITLKYL----KG-------K---PVISGLKRISTPGRRVYVGAHKIPRVQNGLGICIL STSSGVLDGMTAHEKKVGGELLCEIWVSSDRIRIKLKAYDYRILDKAVAEIVDTARNTGAGVAGPIPLPTNIHKYTIQRS VHVDKKSR-EQFEMRIHKRLMDILEPTQQTVDALGKLSLPAGVDVEIKLGRTLTGIVVSDKNDKTIVVRVETLVKHPLLK KYVRRRKKFTAHDPM--NECGMGDKVKIVEFRPLSRNKRWHLVSIIEKA------------------------------- -MPRSL-KKGPFVDG-HLMKKVDTAVA---NSDRR----VLKTWSRRSTILPEMVGLTFAVHNGKKFVPVFVTE-NMVGH KLGEFSPTRTYHGHA------A---DK----KAK----AGRK >DELTA_Desulfovibrio_desulfuricans_G20 Concatenation of 2 sequences MAVRKLKPTSPGRRFQTVSSFEE-ITRS------------TP-ERSLTEGLTKKSGRNCYGRVTSRR-RGGGHKRL---- YRIIDFR-R--DK-VGVPAKVAHVEYDPNRSARIALLHYS-DGEKRYILAPLGVKQGDVVVAGD-S-VD-IKPGNAMALS RVPVGTIVHNIELYPGKGGQFCRAAGTYAQLVAK--EGNYALLRMPSGEVRKVLVTCCATIGQVGNLDHEKISYGKAGRS -RWL-----GRR-P-KVRGVAMNPIDHPLGGGEGRS-S--GGRH-PVTP---WGIPTKGFKTR-DKKKASS-K-LIIKRR --------------------------------EKM---G-ILGRKIGMTRIFA-NDGS---------AVAVTVIQAGPCP VIQVK----DAA----K--DGY--NAVQIGF-------EE--AVNK----------PARGHMK----------------- ---AG-RGLFRVLREIRL--------EAPAEQ-----KV---GD-DLTV--G-L-FTPGEFVKVTGTSIGKGFAGVMKRW NFGG-MPASHGHEAVHRS-PGSIGHA-TFPG-KVWKNKKMAGHMGARQVTVKSLQIIEVRAEDN---------------- ----------LILVKGP-VPGPKNGLVMVR-MAVVKVYD-QDKKET-GELTLAPEVF----EV-EV-RPEILNLVVRAQR AAKRAGTHSVKTRST--------IS-GGGAKPW---------RQKGTGRAR--------SGS---NR-SP----VW---- RGGAVVFGPQ-P-RDYSFKVNKKVRKLALKMALSSRLAEE----------------N-LMVVKGI----ELP-E------ --VKTKLVV--TPEMD--D---KLVLSARNIPGIT-L---------------MTPEQLSVFEILKHAQ----LVLLEGAV EPVQTRLQNIYREQV----APVLQKEFNYKSSMQLPKLEKISLNIGLG-EASQNQKLLEEAVKELTAIAGQKAVITRAKK SIASFKLREGMPIGCRVTLRGDSMWDFLDKLMNFALPRVRDFRGIAD-RGFDGRGNFTLGIKEHTIFPELE-----VDRV DNPKGMNITIVTS-----------------------AKTDKEGKFLLDKLGMPFMSRIG-K--QPIPVPSGVEVK-L--- ---G-AD-VVEVKGPKGSLTTPV--SP-L--LKYEIQD-GS--VVI----T-R--VEEKKAS-AQHGLRRTLLANCIEGV SKGFSKVLEVNGVGY--KVAVKG-NN--IELA--LGFSHPVVIEL-P-K-GIEAAAA--G-N-KLTISG-FDKQLVGEVA ANIRRVR------PPEPY---KGKGVKYEHEQIRRKAGK----------MIQVESALQVADNSGAKKVACIKVLG-SKRR Y--ASVGDVIVVSVKEALPH-S-------KVKKGDVMKAVVVRTAKEIRRNDGSYIKFDTNAAVLLN-KQGE-PVGTRIF GPVARELR-ARNYMKIVSLAPEVLMR-L--HELYPFDEE-RKQRKRVG-RGSGSGW-GCTSGKGNKGQNARSGGG-V--- -RPGF-E-GGQMPLQRRLPK-RG--FKNINLGQLITLDDIYAR-GLARVK---------VLG--NGE-C-N-V-A-VKV- EAHKFSASAVEKIQKAGGEA-K---RQK--GRL---KGDA-LKGNNVAFG----------EIGLKVL--EHGKLTSQQIE AARVAAMRHI------KRGGKMWIRIFPDQPYTAKPLETRQGKGK---------GAPVGWYAPVKP-GRVLYEI--KG-- VNLELAREALTRAAHKLPVKTTI-VKNESRMRRKIRIRKKV---SGNGARPRLVVYRSNLHIYAQLVDD---Q--TGTTL AATSTL-ALGK-QNGN----ALR-LTVDNASLVGKEIAKL--AKEKN-IERVVFDRNGYIYH--GRIKAVADGAREAGLE F--------------------------------------------------------------MQ-AKATAKFVRVSPRK ARLVAQNVKGKPVEDAMNILRFT---------------------------------PQKAGGLIFKVMHSALAN----A- EQLP-GIDVDAMVVKQVIINEGPTWKRFLPRSMGRANRILKRTSHITVILEEQFRIRKDDKVMVISGK------DK-GKI GKVLKVLRKKD--RVL--VEKVNVAKRHMR----AN--PYLQQP-GGIVDKEMPIHISNVK-VMCDAC-------AK--A --TTVGYRY---TE--------DGKVR---FCKKCN---EII--MGQKVHPFGFRLG--YN-KNWQSRWFS------K-K E--YASFVFEDHNIRKYV--KKTLY-----HAGLSKIEIERAG-G-KVRLILSTARPGIVIGRKGVEIEKLRADLRRKFS IEVNEIRR---PETDAQLVAENIAMQLERRVAFRRAMKRTVSMSRKF-GAEGIKVACAGRLAGAEIARSEWYRDGRVPL- -QTLRADIDYGYAEAHTTYGIIGVKVWIF-MLTDPIADMLTRIRNAHLALHKEVSV-PRSKMKEALAAILKEEGYITDFK MEE---------------SSIVIELKYF----KG-------K---PVISGLKRISKSGRRVYVGSTDIPRVQNGLGICIL STSSGVLEGTNARSKNVGGELLCEIWVSSDRIRIKLKAYDYRILDKAVAEIVDTARNTGAGVAGPIPLPTNIHKFTVNRS VHVDKKSR-EQFEMRIHKRLMDILEPTQQTVDALGKLSLPAGVDVEIKLGRALVGVVVSDKNDKTIVVRVETLVKHPLLK KYIRRRKKFTAHDPN--NECKVGDKVKIIEFRPVSRNKRWHLVSILEKA------------------------------- -MPRSL-KKGPFIDD-HVMKKVEKAQE---SGDRR----VIKTWSRRSTISPEMVGLTFAVHNGRKFIPVFVTE-NMVGH KLGEFSPTRTYYGHA------A---DK----KSK-----AKR >DELTA_Desulfovibrio_vulgaris_Miyazaki_F Concatenation of 2 sequences MAVRKLKPTSPGRRFQTVSDFEE-VTRS------------TP-EKSLTEGLTKKSGRNNNGRVTMRR-RGGGHKRL---- YRIIDFR-R--NK-LGIAATVAHIEYDPNRTARIALLHYA-DGEKRYILAPLGIKQGDMVQAGE-G-AD-IKPGNAMPMA RIPVGTVLHNIELYPGRGGQFCRAAGTYAQLVAK--EGKYALLRMPSGEVRKVLAACCATIGQVGNVNHENISLGKAGRN -RWL-----GRR-P-KVRGVAMNPIDHPLGGGEGRS-S--GGRH-PVTP---WGVPTKGYKTR-DRKKAST-K-LIVKRR --------------------------------EKL---G-ILGRKVGMTRIFA-SDGS---------AVAVTVIQAGPCP VIQVR----NGE----T--DGY--DAVQIAF-------EE--AVTK----------PARGHFK----------------- ---AG-KGLFRNLREIRL--------EAPAEF-----EV---GQ-ELTV--S-L-FAAGEKVKVTGTSIGKGYQGVMRRW NFAG-SKDTHGCEKVHRS-GGSIGNN-TFPG-HVFKGKKMAGHWGDERVTVKNLEIVDIRAEDN---------------- ----------VILVKGA-VPGPKNGLVLVR-MAVVKVYD-QNKKEA-GELTLAPEVF----EV-EV-KPEILNLVVRAHR AGLRSGTHATKTRAF--------VS-GGGAKPW---------RQKGTGRAR--------SGS---NR-SP----IW---- RGGAVIFGPQ-P-REYGFKVNKKVRQLALKMALSSRLAGE----------------N-LMVVKGI----ELP-E------ --IKTKLVI--TAEAD--T---TLALSARNIPGIT-L---------------ITADQLSVYEILKHPK----LVMFEGAV ESVQTRLEQIYREKV----VPVLQKEFNYTSSMQVPGIEKVSLNIGLG-AASQNNKLMEEAIKELTAIAGQKAVVTRAKK SIASFKLREGMPIGCRVTLRKERMWDFLDKLMNFALPRVRDFRGIPD-RGFDGRGNFTLGIKEHTIFPELE-----VDRV DNPKGMNITIVTT-----------------------AQTDKEGKLLLDQLGMPFMSRIG-K--LPIAIPSGVEVK-V--- ---G--TEAVEVKGPKGVLVTPT--HT-E--LNYAVED-GH--VVI---TR-A--TETRTAR-AQHGLRRTLLANCIQGV TKGFSKTLEVIGVGY--KVAVKG-NL--VELA--VGFSHPVIMEM-P-E-GVEAKVE--G-Q-KLTISG-TSKEVVGEIA ARIRRVR------KPEPY---KGKGIKYDNEQIRRKAGK----------MIQVESTLQVADNSGAKKVACIKVLG-SKRR Y--ATVGDIVVVSVKEALPH-C-------KVKKGDVMQAVIVRTRKEVRRVDGSYIKFDSNAAVLLN-KQGE-PVGTRIF GPVARELR-GKNFMKIVSLAPEVLMR-L--HELYPFAEE-RASRKRVG-RGSGSGL-GCTSGKGNKGQNARAGGG-V--- -RPGF-E-GGQMPLQRRLPK-RG--FKNINLDRLITLEDIYAR-GLCKVK---------ILG--VGE-V-S-V-A-LTV- EAHKFSASAAEKIRNAGGEA-K---WQK--GRL---RGMA-TRGATVSFG----------DIGLKAV--EHGKLSSQQIE AARIAMMRHI------KRGGKVWIRIFPDHPVTAKPLETRQGSGK---------GAPVGWCAPVKP-GRVLYEI--KG-- VSLELAKEALTRAAHKLPIKTTI-VKNDARKRRKVRIRKKI---AGSTERPRLVVYRSNLHVYAQIVDD---A--TGATL VATSTL---AIGKAQA----GAH-CNKAGAELVGKEIARL--AGEKS-IKRVVFDRNGYLYH--GRIKAVADGAREGGLE F--------------------------------------------------------------ME-SRATAKFMRVSPRK ARLVAQNVNGLPVEDAMNILKFT---------------------------------PNKPADIIFGVLRSALAN----A- EQLP-GIDVDAMVVKQIVINEGPTWKRFLPRAQGRATKIRKRTSHITVILAEQFRIRKDDKVVVIAGK------DK-GKI GKVLKVLPKKD--GVL--VEKVNMVKRHMR----AN-PYR-QQP-GGIIEKEMPLDISNVM-VMCDAC-------AK--A --TKVGYRY---TE--------DGKVR---FCKKCN---EII--MGQKVHPYGFRLG--YN-KNWQSRWFS------K-K E--YPGFVFEDHNIRKFV--KKTLY-----HAGLSKIEIERAG-G-KVRLILSTARPGIVIGRKGVEIEKLRGDLRKKFS IEVNEIRR---PEVEAQLVAENIALQLERRVAFRRAMKRTVSMSRKF-GAEGIKVTCSGRLAGAEIARTEWYRDGRVPL- -QTLRADIDFGFAEARTTYGVIGVKVWIF-MLTDPIADMLTRIRNAHLALHKEVSV-PRSKIKESIAAILKQEGYIEDVA TEE---------------AEIKISLKYF----KG-------K---PVISGLKRVSKPGRRVYVGSTDIPKVQNGLGICIL STSSGVLAGTQARDRKVGGELLCEIWVSSDRIRIKLKAYDYRILDKAVAEIVDTARNTGAGVAGPIPLPTNIHKYTVNRS VHVDKKSR-EQFEMRIHKRLMDILEPTQQTVDALGKLSLPAGVDVEIKLGRVLTGIVVSDKNDKTIVVRVETLVQHPLLK KYVRRRNKFTAHDPQ--NECGIGDKVKIIEYRPLSRNKRWHLVSILEKA------------------------------- -MPRSL-KKGPFIDD-HLIKKVELAVS---NSDRR----VIKTWSRRSTIAPEMVGLTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRTFYGHA------A---DK----KSK-----AKK >DELTA_Desulfovibrio_vulgaris_vulgaris_Hildenborough Concatenation of 2 sequences MAVRKLKPTSPGRRFQTVSDFEE-ITRS------------TP-EKSLVIGLTKKSGRNNNGRVTSRR-RGGGHKRL---- YRIIDFR-R--DK-AGIPAKVAHIEYDPNRTARIALLHYA-DGEKRYILAPVGIRQGDMILSGE-G-AD-IKPGNALPMS RIPVGTNLHNIELQPGRGGQFCRAAGTYAQLVAK--EGKYALLRLPSGEVRKVLAACCATVGQVGNVNHENISLGKAGRA -RWL-----GNR-P-KVRGVAMNPIDHPLGGGEGRS-S--GGRH-PVSP---WGMPTKGYKTR-DRKKASS-K-LIIKRR --------------------------------EKM---G-ILGRKIGVTRIFA-SDGS---------AVAVTVIKAGPCP VTQVK----TVA----T--DGY--DAIQIAF-------DE--ALNK----------PEIGHLK----------------- ---AG-KGLFRTLREIRL--------EAPAAY-----EV---GS-ELDV--T-L-FATGDRVKVSGTSIGKGYQGVMRRW NFAG-SKDTHGCEKVHRS-GGSIGNN-TFPG-HVFKGKKMAGHWGNESVTVLNLEVVDVRPEDN---------------- ----------VILVKGS-VPGPKNGLVMVR-MAVVKVYD-QNKQEA-GEITLAPEVF----EV-EV-RPEILHLVVRAQR AAFRAGTHATKTRAF--------VS-GGGLKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGAIIFGPQ-P-RDYEFKVNKKVRKLALRMALSSRLAGS----------------N-LLVVKGF----ELP-E------ --VKTKLII--APEEN--T---TLALSVRNIPGIT-I---------------ATPEQLSVYEILKHKQ----LVLVEGAV ASVQTRLENIYREKV----VPVLQKEFNYDSSMQVPGIVKVSLNIGLG-AASQNNKLMEEALKELTVIAGQKAVVTRAKK SIASFKLREGMPIGCRVTLRKERMWDFLDKLINFALPRVRDFRGVPD-RGFDGRGNFTLGIKEHAIFPEME-----ADRV ENPKGMNITIVTT-----------------------ATTDKEGKLLLDQLGMPFMSRIG-K--QPIPIPSGVEVK-I--- ---G-ND-VVEVKGPKGALTTPV-CSV----LSYEVTD-GK--VVI----T-R--LDERQTR-AQHGLRRTLLANCIEGV SKGFSKTLEVVGVGY--KVAVKG-DV--VDLS--VGYSHPVLIDL-P-A-GISAKAE--G-N-KLTISG-VDKELVGEVA AQMRRVR------KPEPY---KGKGIKYDNEQIRRKAGK----------MIQVESTLQVADNSGAKKVACIKVLG-SHRR Y--ATVGDIIMVSVKEAMPH-C-------KVKKGDVMQAVIVRTAKEVRRADGSYIKFDSNAAVLLN-KQGE-PVGTRIF GPVARELR-ARNFMKIVSLAPEVLMR-L--HDLYPFPEE-RKTRKRVG-RGSGSGL-GCTSGKGNKGQNARAGGG-V--- -RPGF-E-GGQMPLQRRLPK-RG--FKNINLARLITLDDIYDR-GLCSVK---------ILG--EGD-V-T-T-A-IKV- EAHKFSASAVEKIRNAGGEA-K---WQK--GRN---KGVA-TRGATVAFG----------DIGLKAI--EHGKLTSQQIE AARIAMMRHI------KRGGKVWIRIFPDRPVTAKPLETRQGSGK---------GSPVGWCAPVKP-GRVLYEI--KG-- VSLELAKEALTRAAHKLPVKTVI-VKNEARLRRKVRIRKKI---SGTAERPRLVVYRSNLHIYAQIVDD---T--TGSTL VATSTL---SISRTQE----GVH-ANKAGAELVGKEIARL--AKDKD-IQSVVFDRNGYLYH--GRIKAVADGAREAGLE F--------------------------------------------------------------ME-SRATAKFMRVSPRK TRLVARNIDGLPVEDAMNLLRFT---------------------------------PNKPAGVLYDVLRSALAN----A- QQMP-GVDVDAMVVKQVVVNEGPSWKRFLPRAQGRATRIKKRTSHITVILAEQFRIHKDDKVMVIAGK------DK-GKI GKVLKILRNKD--RIL--VEKVNVAKRHVR----PN-PYR-QQP-GGIIEKEMPLHVSNVM-VVCDAC-------AK--P --TKVGYRY---TE--------DGKVR---FCKKCN---EII--MGQKVHPFGFRLG--YN-KNWQSRWYS------K-K E--YPAFVFEDHNIRKFV--KKTLY-----HAGLAKIEIERAG-G-KVRLILSTARPGIVIGRKGVEIEKLRADLRKKFA IEVNEIRR---PEVESQLVAENIALQLERRVAFRRAMKRTVSMARKF-GAEGIKVTCSGRLAGAEIARTEWYRDGRVPL- -QTLRADIDFGFAEARTTYGVIGVKVWIF-MLTDPIADMLTRIRNAHLALHKEVSV-PRSKMKESLAAILKQEGYIEDVA TEE---------------GSIKLTLKYF----KG-------K---PVISGLKRVSKPGRRVYVGMHEIPKVQNGLGICIL STSRGVMDGNSAHESKVGGELLCEIWVSSDRIRIKLKAYDYRILDKAVAEIVDTARNTGAGVAGPIPLPTNIHKFTVNRS VHVDKKSR-EQFEMRIHKRLMDILEPTQQTVDALGKLSLPAGVDVEIKLGRTLVGIVVSDKNDKTIVVRVETLVKHPLLK KYVRRRKKFTAHDPM--NECGIGDKVKIIEFRPLSRNKRWHLESILEKA------------------------------- -MPRSL-KKGPFVDG-HLMKKVDMAVA---NSDRR----VIKTWTRRSTILPEMVGLTFAVHNGKKFMPVFVTE-NMVGH KLGEFAPTRTYHGHA------A---DK----KSK-----AKK >DELTA_Geobacter_bemidjiensis_Bem Concatenation of 2 sequences MAIKTYKPTSPGRRAQTCSTFEE-ITAC------------KP-ERSLVENLKKSGGRNSNGRITSRN-VGGGHKQK---- YRIIDFR-R--DK-TEIPAKVATIEYDPCRSARIALLNYA-DGEKRYILAPLSLKVGDTVISSE-Q-AD-IKPGNALPIR CIPLGTIIHNIELKIGKGAQLARSAGTFAQLMAK--EGKYGQVKLPSGEVRMILMDCKATIGQVGNADHENVSIGKAGRS -RWL-----GVR-P-HVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-TNKR-ST-P-FIVKKR --------------------------------MNK---G-LIGKKLGMTQIFA-EDGR---------RIAVTVVEAGPCV VVQKK----SVA----K--DGY--SAIQVGF-------GA--KANA----------AQVGHCG----------------- ---AG-AGVFTHYRELRM--------DNTDAY-----KL---GD-VIEA--A-V-FEEGDLVDVTGTSIGKGFAGVIKRW GFKG-GRSSHGS-RFHRA-PGSIGCS-ATPS-RVFKNKKMPGQLGNEKVTVQRLKVVRVDAADN---------------- ----------LILLGGA-IPGSANGVVLIK-MAKLDVFD-IKKAKV-GEIELDDAVF----ND-DV-REYLIHEAVKIQL ANRRQGTVAVKNRAL--------VA-GSGKKPF---------KQKGTGQAR--------QGC---RR-AP----QY---- PGGGVAFGPQ-P-KDYNLSMNKKARKAALRSALSMLYKKD----------------A-ITVVNSL----ELP-S------ --IKTKLVI--TDTAT--P---TLELSARNVKHVK-V---------------LGPEGLNIFDIMKYQS----VVFTEAAV RRVEARLAELYNKEM----VPALMKDQNYKNIMEVPKLVKIVVNMGLG-EAIQNVKILDSAAEELAAITGQRPVITKAKK SIAGFKLRQGMPIGCAVTLRREKMYEFLDRLVSVSLPRVRDFKGISG-KAFDGKGNYSLGVKEQLIFPEID-----YDKV DKIKGLNITIVTT-----------------------AKTDAEGKALLKLMGLPFMSRIG-K--LPIAIPAGVKVIYN--- -A-P----EIKVEGPKGKLARNI--GE-G--VAIDVTA-QA--VTV---TR-H--DDTIKSR-SAHGLTRTLINNMVIGV SKGFETLLEINGVGY--RAEVKG-NV--LNLA--LGFSHPVNFEL-P-T-GITVEVE--K-MTKLKVMG-IDKEVVGETA AKIRAFR------PPEPY---KGKGVKYADETILRKAGK----------MIQMQTLLDVADNSGAKKLFCIKVLG-SKRR Y--AGIGDIIVASVKEALPN-S-------KVKKGDVVKAVVVRTAKAVGRPDGSYIRFDTNSGVVIN-NAKE-PVGTRIF GPVARELR-AKKFMKIISLAPEVLMQ-L--NTIKPAIGS-TKNRKRIG-RGVGSGH-GKTATKGHKGQKARSGGS-V--- -KPGF-E-GGQMPMHRRLPK-RG--FTPVNLCQLIDAEALLKS-GIISIK---------VLA--TGD-I-T-R-A-LTI- KAHKFSASAREKITAAGGSI-K---QMK--GRM---TGTP-QRGVELAFG----------DFGLQAT--ECGWLDSRQIE AARIAMTRYI------KRGGKIWIRIFPDKPLTSKPAETRMGKGK---------GSPDSWVCVIKP-GRILYEM--EG-- VTEEVAREAFRLAAHKLPVASKF-IKQVARLKRQTRVRKKI---TGSPARPRLNVFKSARHIYAQLIDD---T--TGATL ASASTL-AGDV-AEGL----SYT-GNAEAAAKVGAAIAKK--ALEKE-ITAVVFDRNGFLYH--GRIKALADAARENGLS F--------------------------------------------------------------ME-SSAKLSSVRLSPRK TRLVVDLVRGKGIQTALNTLRFS---------------------------------PQPSAKLISKLLSSAVAN----A- EQKG-CSDVDKLFVKTIFVDGGAVLKRFTPRAMGRASKIRKPTSHITVVLAEKLHVKKNDTVVVIAGK------DR-SKS GKVISIHPKKD--GVI--VEGVNVVKRHQK----PR-----GSEQGGILEKEAPVHISNVM-LLCGKC-------NK--P --VRTKTTV---LE--------DGKAR---CCVKCG---ESF--MGQKVNPIGFRLG--VI-KTWDSKWYA------E-K D--YAKLLHEDLKLRNFL--KKRLY-----HSGVSKIEIERAA-G-KAKINIFTARPGLIIGKKGSEVETLKKELAKLVY LNIQEVRK---PELDAQLVAENVAMQLERRIAFRRAMKKSVTSTLKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLLFMCMTDPVADMLTRIRNAGMAKHQKVDI-PSSNLKVSLATVLRAEGFIKNFK VIA----D---N----KQGILRVYLKFI---DEK-------E---PVINEIKRISKPGGRVYVNSDKIKQVKNGLGVAIL STSKGLVTDKTAREMGIGGEVLCTVWMPSQKIRIRLKAYDHKLLDTSVGEIVDTAKRTGARVAGPIPLPTVINKYCVLRG PHVDKKSR-EQFEIRTHKRLIDILEPTQQTVDALMKLDLSAGVDVEIKLRKTQVGVVVSDKMDKTAVVKVDRLVKHPVYN KYIKRSAKYKAHDMD--NAAKIGDRVLIVETRPLSKDKRWKIRQIIESK------------------------------- -MARSI-KKGPFVDG-HLEAKAQAEQA----GSKK----VIKTWSRRSTIIPEFIGLTFAVHNGKKFIPVFVTE-NMVGH KMGEFSPTRTFYGHA------A---DK----KSK----LKKK >DELTA_Geobacter_lovleyi_SZ Concatenation of 2 sequences MAIKSYKPTSAGRRHQTCSTFEE-ITST------------TP-EKSLLVKIKKTGGRNHFGRVTARH-QGGGHKQK---- YRMIDFR-R--DK-RGIPAKVATIEYDPNRSARIALLHYT-DGEKRYILAPLDLKVGDTVLSGP-E-AD-IKPGNSLPLR SIPLGTIIHNIELKIGKGAQLARSAGTFAQLMSK--EGKYSQVKLPSGEVRLVLQDCYATIGQVGNIDHENVCLGKAGRS -RWL-----GKR-P-KVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-TNKT-SD-R-FIVKKR --------------------------------MNK---G-IIGKKLGMTQIFL-EDGT---------RVPVTVVQAGPCV VLQKK----TAE----V--DGY--SAVQVGF-------ET--VANS----------ADRGHCK----------------- ---AG-KGVFRHLRELKL--------EQEAEL-----NI---GD-ELTV--Q-Q-FEPGDLIDVTGTSIGKGFQGVIKRH NFKG-GRASHGS-RFHRA-PGSIGCS-ATPS-RVFKNKKMPGQMGNERVTVQRLQVVRVDADQN---------------- ----------LILIKGA-IPDSKNNVVVIK-MPTIALYN-MNREKI-GEVALDEQIF----AA-EV-KEPLIHQALKVQL ANRRAGTVKTKTRAE--------VS-GGGKKPF---------KQKGTGNAR--------QGC---SR-AP----QY---- PGGGTVFGPQ-P-KTYNLGINKKARKAALRSLLSMQLKSE----------------K-ITVLDQI----EFA-K------ --ISTKLII--TEEPS--T---NLALSSRNVPYVK-L---------------LKADGLNVFDVLKYQN----IVMTEGAV RLVEARLKDVYQNEV----VQKLRAEFNYKNIMEVPRIEKVVINMGLG-EAIQNVKILDSAASELGKITGQKAVITKAKK SIASFKLREGMPIGCMVTLRRERMYEFLDRLMNVALARVRDFKGVSG-KAFDGQGNYTLGIKEQLIFPEIN-----YDEI DKIKGLNVTIVTS-----------------------AKNDEEGKALLKHMGMPFMSRIG-K--LPIEVPKGVTVTFV--- -D-S----VLTVKGPKGELCRTI--MP-E--VSVAVED-GK--ISV---TR-P--DDAIKSR-SAHGLTRTLVNNMVVGV TAGYQTDLEINGVGY--RAEVKG-AE--LVLS--LGYSHPVVFPL-P-S-GITVEVD--K-MTKLAVKG-IDKELVGQTA AKIRSFR------GPEPY---KGKGIKYATETILRKAGK----------MIQMQTILDVADNSGAKKLFCIKVLG-SKRK Y--AGVGDIVVCSVREALPN-S-------KVKKGDVVKAVIVRTAKELGRPDGSYIRFDNNSGVVIN-NAKE-PVGTRIF GPVARELR-AKKFMKIISLAPEVLME-L--NSLRPALGS-TKNRKRIG-RGIGSGH-GKTATKGHKGQKARSGGS-I--- -KPGF-E-GGQMPLQRRLPK-RG--FRPINLQQLVDRDAMNAK-GLLKIK---------VLA--NGD-L-T-K-A-LTI- KADKFSKSAIDKIQAAGGKI-K---QMK--GRM---TGAA-CRRIEISYG----------EFALQAT--ECGWVDSRQIE AARIAMTRYI------KRGGKIWIRMFPDKPLTAKPAETRMGKGK---------GSPDSWVCVVKP-GMVLYEM--EG-- VTEEIAREAFRLAAHKLPISTKF-IKTITRLKRQVRVRKKV---TGTAERPRLNVFRSANHIYAQLIDD---V--QGVTL AAASTC-TEGV-AQSG----VHT-GNKASAAAVGAAIARV--ALQKD-IRSVVFDRNGFLYH--GRIQALADAAREAGLD F--------------------------------------------------------------ME-SSAKLSLARLSPRK TRTVADLVRGKGIQQALNTLSFL---------------------------------PNPSAQILLKLLKSAVAN----A- EQKG-VNDIDKLFVKTIFVDGGAVLKRFVPRAMGRASKIRKPTSHISVVLSDKYHVAKGDTVMVIAGK------EK-AKT GKVLQVLPKKD--AVI--VEGLNMVKRHVR-------ARG-NEP-GGITEKEAALHVSNVQ-LYCTKC-------VK--P --VRTRIKV---LE--------NGKQR---TCVKCD---SSL--MGQKVNPIGFRLG--VI-KTWDSKWYA------E-A D--FAKNLHEDLKIRQFL--KKRLY-----SAGISKIEIERAA-N-KTKINIHAARPGLIIGKKGAEVELLKKDLAAIVF ININEVRK---PELDAQLVAENVALQLERRIAFRRAMKKSVTSSLKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLIFMSMTDPIADMLTRIRNANMVKLQKVDI-PSSNVKVNIAQVLKQEGYIKNYK VIA----D---N----RQGVLRVYLKFI---DEK-------D---PVINEITRISKPGSRTYVDSESIPTIKNGLGIAIL STSKGIMTDASARQAGIGGELLCTVWMQSQKIRIRLKAYDHKLLDVSVGEIVETAKRTGARVAGPIPLPTVINKYCVLRG PHVDKKSR-DQFEIRTHKRLIDILDPTQQTVDALMKLDLSAGVDVEIKLRRTQTGVVVSDKMEKTVVVRVDRLVKHPLYN KYIKRSVKYKVHDEK--NSCKAGDKVQIVECRPLSKDKRWALRQILESA------------------------------- -MARSI-KKGPFVDG-HLMKKVETEGP----NSKK----IIKTWSRRSTITPEFIGVSLAVHNGKKFIPVFVTE-NMVGH KLGEFSPTRTFHGHA------A---DK----KSK-----VKK >DELTA_Geobacter_metallireducens_GS-15 Concatenation of 2 sequences MAIKTYKPTSAGRRHQTCSAFDE-ITTS------------SP-EKSLLLTLKKTGGRNSFGRITSRH-IGGGHKKK---- YRLVDFR-R--NK-IDIPAKVASIEYDPNRSARIALLHYS-DGEKRYILAPLNLKVGDVVLAST-S-AD-IKPGNSLPLR AIPLGTIIHNIELKIGKGGQLARSAGTFAQLMAK--EGKYAQVKLPSGEVRMVLLDCMATVGQVGNIDHENVTIGKAGRS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-KNKT-SS-R-FIVKPR --------------------------------MKK---G-LIAKKLGMTQIFA-DDGR---------RIPVTVVEAGPCI VLQKK----TVE----T--DGY--NAIQVGF-------LA--KSGR----------ALVGHCS----------------- ---AG-QGVFTYIREFRV--------EDVDRY-----TI---GD-SITA--E-I-FAPGDYVDVTGTSIGKGFQGVIKRW GFRG-GRSSHGS-CFHRA-PGSIGSS-AWPS-RVFKNKKMPGQLGNERVTVQRLQVVRVDTADN---------------- ----------LLLIRGA-IPGAKNGILLLKVMATIDVFD-INKNKV-GEMDLSDAVF----NG-DV-REYLIHEAVKVQL ANRRAGTVGVKNRAA--------VS-GGGKKPF---------KQKGTGQAR--------QGC---IR-AP----HY---- VGGGVAFGPQ-A-KTYALSMNKKARKAAVRSALSMLFKEN----------------K-LSVLDCL----SLP-S------ --ISTKLVI--IDEAN--T---NLELSARNVKDVK-V---------------LKAEHLNVFDIVKFNN----IILTQSAV RKIEARLNELYKNEI----VPQLTKDFGYSNIMQVPKIEKIVVNMGLG-EAIQNVKILDSAVEELAMITGQKSVITKAKK SIASFKLRQGMPIGCMVTLRREKMFEFLDRLINVALPRVRDFKGVSG-KGFDGRGNYSLGIKEQLIFPEIE-----YDKI DKIKGLNITIVTS-----------------------ARSDEEGKALLKQLGMPFMSRIG-K--RPIEIPSGVKVSYV--- -T-P----ILKVEGPKGSLLREI--MS-D--IALEIEE-KS--VSV---NR-A--DDAIKSR-SAHGLTRTLINNMVVGV TKGFEKILEINGVGY--RAEAKG-DV--LSLS--LGYSHPINFPL-P-K-GITVEVD--K-MTKVFVRG-IDKELVGQTA AKIRSFR------GPEPY---KGKGIKYADERILRKAGK----------MIQMQTILDVADNSGARKLFCIKVLG-SKRK Y--AGIGDIIVASVREAIPN-S-------KVKKGDVVKAVIVRTAKEVGRLDGSYIRFDDNSAVVIN-NQRE-PVGTRIF GPVARELR-ARKFMKIVSLAPEVLME-L--NNLKPAIGA-TKDRKRIG-RGTGSGH-GKTATKGHKGQKARSGGS-I--- -KAGF-E-GGQMPMQRRLPK-RG--FTPVNIGQLVDAEALLNA-GLISIK---------VLA--DGD-V-T-K-S-LVV- KVHKYSAKAKEKIEAVGGKI-K---QMK--GRM---TGAA-MRGATLSYG----------DFGLQAT--ECGWVDSRQIE AARIAMTRYI------KRGGKIWIRMFPDKPLTSKPAETRMGKGK---------GSPDSWVCVVKP-GKVLYEM--EG-- VSEEIAREAFRLAANKLPVGTKF-IKKVAHLKRKTRVRKKI---RGTTDRPRLNVYKSARHIYAQIIDD---V--TGVTL VSASTV-QDE--SDAL----KYT-GNVEAAKCVGAMVAKK--ALEKN-ITSVVFDRNGFLYH--GRVKALADSARENGLS F--------------------------------------------------------------ME-ARAKLSFARLSPRK TRLVVDMVRGRGIQDALTILRFS---------------------------------PQPSAKLVSKLLQSAVAN----A- EQKG-ASDVDRLFVKTIFVDAGPVLKRFTPRAMGRASKIRKPTSHVTVVLADKFHVKKGDTVSVIAGK------DK-SKT GKVIRILPKKD--GVL--VEGLNMVKRHMR-------ARG-NEP-GGIVEKENPLHVSNVM-LYCDKC-------KK--P --VRSKMNV---LE--------DGKVR---VCIKCG---DSF--MGQKVNPIGFRLG--VI-RTWDSRWYA------E-A D--YAKLLHEDIKLRNFL--KKRLF-----NSGVSKIEIERAA-S-KAKINIFTARPGLIIGKKGAEVETLKKELAKLIY LNIQEVRK---PELDAQLVSENVALQLERRVAFRRAMKKSVTSALKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLIFMSMTDPIADMLTRIRNASMAKLQKVDI-PSSNLKVSLANVLKAEGFIKNFK VIA----D---N----KQGVLRVYLRFI---DEK-------E---PVIREIKRVSKPGSRVYVGSDEIPSVKSGMGVAIL STSKGILTDKVAREAGVGGEVICTVWMPSQKIRIRLKAFDHKLLDQSVGEIVDTAKRTGARVAGPIPLPTIINKYCVLRG PHVDKKSR-EQFEIRTHKRLIDILDPTQQTVDALMKLDLSAGVDVEIKLRKTQVGIVVSDKMDKTVVVQVSHLVKHPVYN KYIKRSVKYKAHDEE--NSCKSGDRVQIVETRPLSKDKRWRVRQIIDRF------------------------------- -MARSI-KKGPFVDD-HLAKKV-AAEG---TGSKK----VLKTWSRRSTITPDFIGLTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRTFYGHA------A---DK----KSK----LKKK >DELTA_Geobacter_sp_FRC-32 Concatenation of 2 sequences MAIKSYKPTSAGRRHQTCSTFEE-ITTS------------QP-ERSLVVKLKKTGGRNNFGRITSRH-IGGGHKQK---- YRIIDFR-R--DK-RDIPAKVASVEYDPYRSARIALLNYA-DGEKRYIIAPLDLKVGDTVVAST-S-AD-IKPGNALPIR SIPLGTIIHNIELKIGKGAQLARSAGTFAQLMAK--EEKYAQVKLPSGEVRMVLMDCMATIGQVGNLDHENVSIGKAGRS -RWL-----GKR-P-KVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-TNKT-ST-R-FIVKRR --------------------------------MNK---G-LIGKKIGMTQIFA-DDGR---------RIPVTVVEAGPCV VIQKK----TKE----K--DGY--NAIQVGF-------DA--KANS----------ATVGHCA----------------- ---AG-SGAFSFFRELRV--------DNVDSY-----NV---GD-VLNA--D-L-FAAGDVIDVTGTSIGKGFQGVIKRW GFKG-GRSSHGS-RFHRA-PGSIGCS-ATPS-RVFKNKKMPGQLGNERVTVQRLKVVRVDAADN---------------- ----------LILVGGA-IPGSTNGLVFIK-MAKLDVYN-TSHKKV-GEIELSDAVF----ND-EV-REYLIHEAVKIQL ANRRAGTVAVKNRAA--------VS-GSGKKPF---------KQKGTGQAR--------QGC---KR-AP----QY---- PGGGVAFGPQ-P-KTYNLSMNKKARRAALRSALSLLFKND----------------K-LTVLDAI----NLD-T------ --VSTKLVV--TDAEN--R---NLELSARNIKNVK-V---------------LKTEGLNIFDLMKYQR----VIFTENSV RKVEARLNELYNKEL----VPQLMKDFNYRNIMQVPKLEKIVINMGLG-EAIQNVKILDSAVSEMALIAGQKPVITKAKK SIAGFKLRQGMPIGCAVTLRREKMYEFLDRLINVSLPRVRDFKGISG-KGFDGKGNYSLGVKEQLIFPEID-----YDKI DKIKGLNITIVTS-----------------------AKNDEEGKALLKLMGMPFMSRIG-K--LPIEIPKGVKISYT--- -D-S----NLQVVGPKGTLSRTI--MS-G--VTIEMTE-NH--ISV---SR-D--DDGIKSR-SAHGLTRTLINNMVTGV TKGFETALEINGVGY--RAELKG-DV--LNLS--LGYSHPINFSL-P-K-GINVEVD--K-MTKILVKG-VDKELVGQTA AKIRDFR------GPEPY---KGKGVKYADETILRKAGK----------MIQMQTILDVADNSGAKKLFCIKVLG-SKRK Y--AGIGDIIVASVKEAIPN-S-------KVKKGDVVKAVVVRTAKEIGRPDGSYIRFDGNSGVVIN-NQKE-PVGTRIF GPVARELR-AKKFMKIISLAPEVLME-L--NSIKPAAGA-SKNRKRIG-RGTGSGH-GKTATKGHKGQKARSGGS-V--- -KAGF-E-GGQMPMHRRLPK-RG--FKPVNLSQLVDVEAMQKS-GLVKIK---------ILA--SGE-L-T-K-S-LTI- KAHKFSAAARDKITSVGGTV-K---QMK--GRM---SGTP-QRGVSLAFG----------DYGLQAT--ECGWLDSRQIE AARIAMNRYI------KRGGKIWIRIFPDKPLTAKPAETRMGKGK---------GSPDSWVCVIKP-GRILYEM--EG-- VTEEVAREAFRLAAHKLPIPTKF-TKKNSRLKRQVRVRKKI---KGTAERPRLNVFKSAKHIYAQLIND---A--DGSTV ASASTL-LDEV-STGL----DYT-GNKEAAQKVGAALAKK--ALAKE-ISKVVFDRNGFLYH--GRIKALAEAARENGLS F--------------------------------------------------------------ME-STAKLSFARLSPRK TRLVVDMVRGKGIQNALNTLRFS---------------------------------PQPSAKLVSKLLSSAVAN----A- EQKG-VADVDRLYVKTIYVDGGTVLKRFVPRAMGRASKIRKPTSHICVVLAEKLHVKKNDTVVVIAGK------DK-AKT GKVLQILPKKD--GIL--VEGVNITKRHTK----PR-----GSESGSIVEKEAVIHVSNVM-IYCSKC-------DK--A --VRTRTNT---LE--------DGKVR---VCVKCG---EAF--MGQKVNPIGFRLG--VI-KTWDSKWYA------E-K D--FAKLLHEDLKLKSFL--KKRLY-----HSGVSKIEIERAA-G-KAKINIYTARPGLIIGKKGSEVETLKKELAKLVY LNIQEVRK---PELDAQLVSENIALQLERRVAFRRAMKKSVTSSLKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLIFMSMTDPIADMLTRIRNAGMAKHQKVDI-PSSNLKVSLANLLRNEGFIKNYK VIA----D---N----KQGVLRVYLKYI---DEK-------D---HVINEIKRVSKPGGRVYVDSDGIPKVKNGLGVAVL STSKGIITDKSAREFGIGGELICTVWMPSQKIRIRLKAYDHKLLDVSVGEIVDTAKRTGARVAGPIPLPTVVNKYCVLRG PHVDKKSR-EQFEIRTHKRLIDILEPTQQTVDALMKLDLSAGVDVEIKLRKTQIGVVVSDKMDKTVVVKVDRLIKHSVYN KYIKRSAKYKAHDVD--NSCKTGDRVLIVETRPMSKDKRWKVRQIIERN------------------------------- -MARSI-KKGPFVDA-HLEAKVQAEGA----SSKK----VIKTWSRRSTITPDFIGLTFAVHNGRKFIPVFVTE-NMVGH KMGEFAPTRTFFGHA------A---DK----KSK----LKKK >DELTA_Geobacter_sulfurreducens_PCA Concatenation of 2 sequences MAIKTYKPTSAGRRHQTCSAFDE-ITTS------------TP-EKSLIVTIKKTGGRNSFGRITARH-IGGGHKKK---- YRIIDFR-R--NK-VEVPAKVASIEYDPNRSARIALLHYA-DGAKRYILAPLDLKVGDSIVASS-N-AD-IKPGNALPLR AIPLGTIIHNIELKIGKGGQLARSAGTFAQLMAK--EGKYAQVKLPSGEVRMVLLDCMATIGQVGNIDHENVSIGKAGRS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-KNKT-ST-R-FIVKKR --------------------------------MKK---G-LIAKKLGMTQIFA-EDGK---------RIPVTVVQAGPCV VLQKK----TSA----T--DGY--DAIQVGF------LSQ---VTK----------PMLGHIK----------------- ---AAGQGAFAHIREFRL--------DDVDRY-----NV---GD-VISA--D-A-FEVGEYIDVTGTSIGKGFQGVIKRW GFRG-GRSSHGS-CFHRA-PGSIGSS-AYPS-RVFKNKKMPGQLGNERVTVQRLQVVRVDAADN---------------- ----------ILLIKGA-IPGAKNGIVLVK-MATIDVFD-ISKNKV-GVMDLNDNVF----NG-EV-KEYLIHEAIKVQL ANRRAGTVSVKNRAI--------VS-GGGKKPY---------RQKGTGQAR--------QGC---IR-AP----HF---- VGGGVAFGPR-P-KVYNLSMNKKARKAAVRSALSMLYKEN----------------K-LSVLDSF----TLP-S------ --ISTKLVV--VDEPN--L---NLELSARNVKDVK-V---------------LKAEHLNVFDIVKYNN----IIVTQSAV RTIEARLKELYHKEI----VEQLTKDFGYSNVMQVPKIEKIVVNMGLG-EAIQNVKILDSAVEELAAIAGQKAVITKAKK SIAGFKLRQGMPIGCMVTLRREKMYEFLDRLINVALPRVRDFKGVSA-KGFDGRGNYSLGVKEQLIFPEIN-----YDKI DKIKGLNITIVTS-----------------------AKTDEESRALLKHLGMPFMSRIG-K--RPIEIPSGVKVE-F--- -S-D--S-VLTIEGPKGKLSRQV--MD-G--VSLEITP-SS--IEV---KR-A--DDGLKAR-SAHGLTRTLVNNMVVGV TKGFERALEINGVGY--RAEAKG-DV--LNLS--LGYSHPINYAL-P-A-GIIVEVD--K-MTKLVVKG-IDKELVGQTA AKIRSFR------GPEPY---KGKGIKYADEKILRKAGK----------MIQMQTVLDVADNSGAKKLFCIKVLG-SKRK Y--AGVGDIVVCSVREAVPN-A-------KVKKGDVVKVVIVRTAKEIGRPDGSYIRFDDNSGVVIN-NQRE-PVGTRIF GPVARELR-AQKFMKIISLAPEVLME-L--NELRPAVGA-TKDRKRIG-RGPGSGH-GKTATKGHKGQKARSGGS-V--- -KPGF-E-GGQMPMQRRLPK-RG--FTPVNVGQLIDVEALLNA-GLIGLK---------VLA--DGD-L-T-K-P-LTV- KAHKFSAKAKEKIAAAGGTV-K---QMK--GRM---KGDA-QRGASLAFG----------EFGLQAT--ECGWVDSRQIE AARIAMTRYI------KRGGKIWIRLFPDKPLTSKPAETRMGKGK---------GSPDSWVCVVKP-GKVLYEM--EG-- VTEEIAREAFRLAAHKLPVGTKF-I--MAHLKRKTRVRKKI---RGTTERPRLNVFKSAQHIYAQIIDD---T--TGTTL VSASTV-QKEA-SESL----NHC-GNVEAAKRVGALIAKR--ALEKN-IATVVFDRNGFLYH--GRIKALADSARENGLT F--------------------------------------------------------------ME-ASAKLTFARLSPRK TRLVVDMVRGKGIQDALTILRFS---------------------------------PQASAKLVSKLLRSAVAN----A- EQKG-ASDVDRLYVKSISVDGGPVLKRFVPRAMGRASKIRKPTSHITVVLADKFHIKKGDTVSVVTGK------DK-SKT GTVLRILPKRD--GVL--VEGLNIVKRHTR----AR--GN-EP--GGIVEKEAPLHVSNVM-LYCGKC-------EK--P --VRAKKAI---LE--------DGKVR---VCVKCG---EAF--MGQKVNPVGFRLG--VI-RTWDSRWYA------E-A D--YSKLLHEDLKLRNFL--KKRLY-----NSGVSKIEIERAA-N-KAKINIYTARPGLIIGKKGAEVETLKKELAKLIY LNIQEVRK---PELDAQLVAENVALQLERRVAFRRAMKKSVTSSLKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLIFMSMTDPIADMLTRIRNANMARLQKVDI-PSSNLKVNLANVLKAEGFIKNYK VIA----D---S----RQGVLRVYLKYI---DEK-------D---PVINEIKRVSKPGSRVYVGSDKIPSVKNGMGVAIL STSKGLITDKSAREAGVGGEVLCTVWMPSQKIRIRLKAFDHKLLDQSVGEIVDTAKRTGARVAGPIPLPTVINKYCVLRG PHVDKKSR-EQFEIRTHKRLIDILDPTQQTVDALMKLDLSAGVDVEIKLRKTQVGVVVSDKMDKTVVVRVSHLVKHPVYN KYIKRSVKYKAHDTD--NSCKTGDRVLIVETRPLSKDKRWKVRQIIDRV------------------------------- -MARSI-KKGPFVDD-HVAKKVAAESA----GSKK----VIKTWSRRSTITPDFIGLTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRTFHGHA------A---DK----KSK----LKKK >DELTA_Geobacter_uraniumreducens_Rf4 Concatenation of 2 sequences MAIKSYKPTSAGRRHQTCSTFEE-ITTD------------KP-EKSLLVKLKKTGGRNNFGRVTSRH-IGGGHKQK---- YRIIDFR-R--DK-RDIPAKVSSVEYDPYRSARIALLNYA-DGEKRYIIAPLDLKVGDTVISGP-S-AD-IKPGNALPIR SIPLGTIIHNIELKIGKGAQLARSAGTFAQLMAK--EDKYAQVKLPSGEVRMVLLDCIATVGQVGNIDHENVSIGKAGRS -RWL-----GKR-P-KVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-TNKT-ST-R-FIVKRR --------------------------------MNK---G-LIGKKLGMTQIFA-EDGR---------RIPVTVVEAGPCV VIQKK----TKE----K--DGY--SAIQVGF-------NS--QANS----------AVVGHCT----------------- ---AG-SGVFSFLRELRV--------DNADQY-----SV---GD-VLSA--E-I-FAPGDLVDVTGTSIGKGFQGVMKRW GFKG-GRASHGS-RFHRA-PGSIGCS-ATPS-RVFKNKKMPGQLGNEKVTVQRLKIVRVDAADN---------------- ----------LILLNGA-IPGSTNGLVLIK-MAKLDVFD-IKNKKV-GEIELSDSVF----ND-EV-KEYLIHEAVKIQL ANRRAGTVGVKNRSA--------VA-GSGKKPF---------KQKGTGQAR--------QGC---RR-AP----QY---- PGGGVAFGPQ-A-KTYNLSMNKKARRAAMRSALSLLFKNN----------------K-LTVLNNI----DLD-N------ --VSTKLVV--TDVEN--R---NLELSARNVKNVK-V---------------LKSEGLNIFDIMKYQS----VIFTENSV RKVEARLNELYNKEM----VPQLMKDFNYRNVMEVPKLEKIVVNMGLG-EAIQNVKILDSAVDEMAVITGQKPIITKAKK SIAGFKLRQGMPIGCAVTLRKDKMYEFLDRLVNVSLPRVRDFKGISG-KAFDGNGNYSLGVKEQLIFPEIN-----YDKI DKIKGLNITIVTT-----------------------AKSDEEGKALLKLFGMPFMSRIG-K--LPIEIPKGVKISYI--- -D-S----NLMVEGPKGSLGRRI--MS-G--VSIDLTD-NT--ITV---SR-D--NDGIKSR-SAHGLTRTLINNMVTGV TTGFETALEINGVGY--RAELKG-DV--LNLS--LGYSHPINFQL-P-K-GINVEVD--K-MTKLLVKG-IDKELVGQTA AKIRAFR------GPEPY---KGKGVKYANETILRKAGK----------MIQMQTILDVADNSGAKKLFCIKVLG-SKRK Y--AGIGDIIVASVKEAIPN-S-------KVKKGDVVKAVVVRTAKEIGRPDGSYIRFDGNSGVVIN-NQKE-PVGTRIF GPVARELR-AKKFMKIISLAPEVLME-L--NSLKPAAGA-SKNRKRIG-RGTGSGH-GKTATKGHKGQKARSGGS-I--- -KAGF-E-GGQMPMHRRLPK-RG--FTPVNLSQLVDIEAMQKS-GLVKIK---------ILA--TGE-L-T-K-A-LTV- KAHKFSATARNKITSVGGTV-K---QMK--GRM---SGTP-QRGVSLAFG----------EFGLQAT--ECGWLDSRQIE AARIAMNRYI------KRGGKIWIRIFPDKPLTAKPAETRMGKGK---------GSPDSWVCVIKP-GRILYEM--EG-- VTEEIAREAFRLAAHKLPIPTKF-TKKTARLKRQIRVRKKI---RGTAERPRLNVFKTAKHIYAQLIDD---T--CGATL AAASTL-LDEV-STGL----SYT-GNIEAAQKVGAAIAQK--ALAKE-INMVVFDRNGFLYH--GRIKALAEAARENGLS F--------------------------------------------------------------ME-SSAKLSFARLSPRK TRLVVDMVRGKGIQNALNTLRFS---------------------------------PQPSAKLVSKLLSSAVAN----A- EQKG-VADVDRLYVKTIYVNGGTVLKRFVPRAMGRASKIRKPTSHICVVLAEKLHVKKNDTVIVITGK------DK-AKT GKVLQILPKKD--GVL--VEGINIVKRHTR----PR-----GSEAGAIVEKEAVIHVSNVM-IYCNKC-------GK--P --VRTRINT---LE--------DGKVR---ICVKCG---EAF--MGQKVNPIGFRLG--VI-KTWDSKWYA------E-K D--YAKLLHEDLKLRSFL--KKRLY-----HSGVSKIEIERAA-G-KAKINIFTARPGLIIGKKGSEVETLKKELAKLVY LNIQEVRK---PELDAQLVAENIALQLERRVAFRRAMKKSVTSSLKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLLFMSMTDPIADMLTRIRNAGMAKHQKVDI-PSSNLKVSLANLLRNEGFIKNYK VIA----D---N----KQGVLRVYLKYI---DEK-------D---PVINEIKRISKPGGRVYVDSDGIPKVKNGLGVAVL STSKGIITDKTARELGVGGELLCTVW------------------------------------------------------ -------------------------------------------------RKTQVGVVVSDKMDKTVVVKVDRLIKHSVYN KYIKRSAKYKAHDID--NSCKIGDRVLIVETRPMSKDKRWKVRQIIERN------------------------------- -MARSI-KKGPFVDT-HLQAKVQAEGP----SSKK----VIKTWSRRSTITPDFIGLTFAVHNGRKFIPVFVTE-NMVGH KMGEFAPTRTFFGHA------A---DK----KSK----LKKK >DELTA_Lawsonia_intracellularis_PHE/MN1-00 Concatenation of 2 sequences MAIRNLKPTSPGCRFQTISDFKE-ITCS------------SP-EKSLTYGLCKKAGRNNHGHITSRR-RGGGAKRL---- YRLIDFK-R--DK-VGVPAKVAQIEYDPNRTARIALLHYV-DGEKRYILAPVGIKQGDIIETGV-D-AD-IKPGNSLPML HIPIGTLIHNIELNPGRGGQLCRSAGAYAQLVAR--EGKYALLRMPSGEVRKVLASGAATVGQVGNIHHENISLGKAGRN -RWL-----GRR-P-KVRGVAMNPVDHPLGGGEGRS-S--GGRH-PVSP---WGMPTKGYKTR-DKKKPSS-R-LIVKRR --------------------------------EKI---G-ILGQKLGMTQVFG-GNGF---------AVPVTVVQAGPCP IVQIK----TVE----K--EGY--NALQIAF-------GE--GVSK----------SMQGHFK----------------- ---AG-LSLYRKIQEVRL-------KGSLTSY-----EV---GQ-VLTV--G-L-FSVGDKVKITGKSIGKGFQGAMRRW NFAG-SKDSHGCEKVHRA-AGSIGNN-TFPG-HVFKGKKMAGHWGTEKVTVQNLVVVDIRPEDN---------------- ----------IILIHGS-VPGPKNSFLFIS-MAIVTVYN-QQKEET-GKINLSSKIF----EV-QV-QPEILHLVVRAQL AAKRAGTHSVKTRGH--------VS-GGGAKPW---------RQKGTGRAR--------AGS---NR-SP----LW---- RGGGIVFGPQ-P-RDYSFKVNKKIRSLALCMALSSRFAEE----------------N-LIVIDNI----VLP-E------ --IKTKLIV--APVES--T---QLLLSMRNVPNVK-L---------------LTYDRLNVYDILKYKQ----LVLLEGAV QHIETRLEKFYQEKV----VPALQKEFLYKSIMQVPTIEKISLNIGLG-VASQSNKIMEEAISELSLIAGQKAVITRAKK SIASFKLREGMPIGCRVTLRKERMWDFLDKLMNFALPRVRDFRGVSE-NGFDGHGNFTLGIKEHSIFPELE-----IDRI ENTKGMNITIVTS-----------------------AVLDSEGKVLLDLLGMPFMSRIG-K--LPIMIPAGVEIT-F--- ---G-EK-NISIKGPKATLVTPK-CEL----LSYEHKE-DK--IIL----T-C--NFDRESL-AQYGLRRTLLANCIEGV TKGFSKTLEVIGVGY--RVSVKG-NI--VELS--VGYSHPVHIEL-P-D-GITAKAE--G-Q-KLTIMG-SDKVLVGEMA ARIRRIR------KPEPY---KGKGIKYESEIIRRKAGK----------MIQVESTLQVADNSGAKKVACIKVLG-SKRR Y--ATVGDIIVVSVKEAIPH-S-------KVKKGEVLQAVIVRTKKEVRRMDGSYIKFDSNAAVLLS-KQGE-PVGTRIF GPVARELR-ARNFMKIISLAPEVLMN-L--TTLYPFLEE-RKLRKRVG-RGSASGL-GCTSGKGNKGQNARSGGG-V--- -RPGF-E-GGQMPLQRRLPK-HG--FKNFNLDWLILLEDIYSH-KLCSVK---------ILG--SGS-I-S-N-I-VTI- EAHKFSRSALKKLHEVGGQA-K---WQK--GRL---RGPA-LRGISIAYG----------DIALKST--EHGKLTSQQIE AARIAMMRHI------KRGGKVWIRVFPDHPITAKPLETRQGSGK---------GSPVGWCAPVKP-GRILYEI--KG-- VNIDLAREALIRAAHKLPVKTVI-VKNKLRQHRKIRIRKKI---FGTADQPRLVIFRSNLHIYAQLVDD---I--TGSTL LTTSTL---SLKDNGI----NIR-ANKSGSTLVGKEIARL--AIEKQ-IIKIVFDRNGYLYH--GRVKAVADGAREGGLK F--------------------------------------------------------------ME-SKACAKFIRVSPRK ARLIASNVKGKTVELAMNILKFT---------------------------------PNKSAGIILGVMRSALAN----A- EHNA-KLDVDTLIVKEVIVNEGPTWKRFMPRAQGRATHIRKRSSHISVVLSEQIRIHKNDKVMVIAGK------DK-GKI GKVLKVCHKHN--RIL--VEKVNIVKRHVK----PN--PY-RREHGGIIEKELPIVTSNLM-IICSSC-------TS--P --TRVHYRY---SE--------SGKLR---ICKKCN---ESL--MGQKVHPYGFRLG--YN-KNWQSRWFS------K-K D--YANFIYEDYKIRSYI--KKLLY-----SAGISKMEIERAG-G-KICLMLSTARPGIVIGRKGVEIEKLRLELRKNFS LEVTEVRR---PEVDAQLVAENIAMQLERRVAFRRAMKRTVSMARKF-GAEGIKITCSGRLAGAEIARTEWYRDGRVPL- -QTLRADIDYGFAEAHTTYGIIGVKVWIY-MMTDPISDMLTRIRNAQLALHKDVAI-PYSKIKYSIANILKEEGYINELT LNN---------------GTITLYFKYY----KG-------K---AAIEGLRRISKSGRRVYVSTHDIPSVQNGLGICIL STSIGVIGCNKARCSKVGGELLCEVWVSSDRIRIKLKAYDYRILDKAVAEIVDTARNTGASIAGPIPLPTNIHKFTVNRS VHVDKKSR-EQFEMRIHKRLMDILEPTQQTVDALGKLSLPAGVDVEIKLGRVLVGTVISDKNDKTIIVHVETLVKHPLLK KFIRHRKKFTAHDPL--NECSIGDTVKIIEFRPLSRNKRWHLVAILEKA------------------------------- -MPRSL-KKGPFVDK-DLMKKVDAAIA---NNDRR----VLKTWSRRSTILPEMVGLTFAVHNGKKFLPVFITE-NMVGH KLGEFSPTRTFYGHA------G---DK----KTK-----AKK >DELTA_Myxococcus_xanthus_DK_1622 Concatenation of 2 sequences MGIKKYKPTSAARRLMTVSDFAD-ITKD------------SP-EKSLTEPLKRSGGRNVHGHITRRH-QGGGHKRR---- YRVIDFK-RR-DK-DGVPAKVVAVEYDPNRTANIALLHYA-DGEKRYILAPVGLSVGDTVFAGE-G-AD-IRPGNSLPLQ NIPVGTVIHNVELKPGRGAQVIRSAGTSGQLMAK--EDRYAQVRMPSGTVRKVLIECRATVGQVGNIEHEIIRIGKAGKS -RWL-----GIR-P-TVRGLAMNPVDHPHGGGEGKS-G--QGNPHPVSP---WGKKTKGLTTR-TNKR-TD-K-FIVSGR --------------------------------MK----G-LIGKKIGMTQVFN-DEGN---------LVPVTVIDVGTCQ VVGKR----TPE----K--DNY--SAVTIGF-------GE--ILNL----------AERGFFK----------------- ---AN-APYRRHLKEFRV------TPEEAASF-----NV---GD-AVKA--D-M-FAKGELVDVTGITKGRGFSGVMRRW NFKGSQTKTHGTHEYQRH-PGAIGQR-KTPG-RVYPNKKMPGHYGVDQVTTQNLTVVDVDVEKG---------------- ----------LVLVKGA-VAGHNNGVVYIR-MAKFDVVD-LDLKKV-SEIELSDDVF----GT-EP-NAHLFYEVAKMQQ INRRRGTVGVKNTSL--------VS-GGGKKPW---------KQKGTGRAR--------QGS---IR-AS----HW---- VGGGKAMAPK-A-RDYFYRPPRKVRRGALKSALSLRAQEK----------------T-LIILDGF----SLD-A------ --PKSKLVI--DDKGN--T---NLHRSVRNLAKFD-V---------------LPPEGLNLEAVLRHSH----LVLTSAAA KTLE----MRFFKEG----VPSLLKELSLKNPMQVPRLEKIVVNMGLG-EALANNKILESAVEQLAAITGQKPIVTRARK SIANFKLRQGQAIGAAVTLRGDRMYEFMDRLITVALPRVRDFKGVSP-KAFDGKGNYTLGVREQIIFPEIN-----YDQI EKVKGLNISFVTT-----------------------AANDEQGLALMRHFGMPFMSRIG-K--LAIKLGDKTKAV-I--- -A-G-E--QVNFEGPKGKLSVKL--PG-K--VKVEIKD-GQ--MTV---QR-E--DDSREAR-SLHGLTRTILANAAKGV STGFEKKLDIRGVGF--RAEVKG-KA--IHFS--LGFSHPVVFNL-P-E-GVTAEVPRNE-DVGLTLRS-SDKEALGATA VNIRSLR------PPEPY---KGKGIKYAEERIRRKEGK----------MIQMTSVLDVADNSGAKKVFCIKVLG-SKRK Y--ASIGDVIVVSVREALPN-S-------KVKKGDVAKAVIVRTKREVGRPDGSYIKFDGNSAVLIN-KDME-PIGTRIF GPVARELR-ARKFMKIISLAPEVLST-L--NKLQRPARS-WHRKKRVG-RGQGSGL-GKTAGRGGKGQKARTGNM-R--- -FEGF-E-GGQSPLQRRLPK-FG--FTPVNLSDLADVETLRKV-GLVKVK---------LLA--RGE-L-T-K-K-VTV- VVHKASEAAKAAIQKAGGAV-K---MHK--GRM---PGSA-HRGSDMTYG----------EYGLMSL--QPGWITSRQIE AARIAMTRHV------KRGGKIWIRIFPDKPITKKPAETRMGTGK---------GGVEYYVAVVKP-GRILYEM--EG-- MTPEVATGALKLAQAKLPVLTKI-VKIEARLKRKNRIRKKL---SGTTERPRLTVYKSLKHIYAQVVDD---T--TGKTL AFASSL-SKDL-KGQ-----DEG-DKKADAKRVGALIAQK--CKAAN-VEAVVFDRNGFPYH--GRIAAVADAAREAGLK F--------------------------------------------------------------ME-STAHLRFLRMSPRK ISTVAELIRGKPVEAALNILKFT---------------------------------KRAAAKPVEKLIKSAVAN----AT DKSKGQVDVDTLYVKTISVDQGPTQRRFMPRAMGRATPIKKKTAHVHVVLAEMQKLKVGDTIQVMAGA------EA-SKR GKVLKIDREAE--RVT--VEGLRLVKRHMK----KT--PQ-SPE-GGIVEKPGTIALANVQ-VVCAKC-------DK--P --TRVGIRT---EG---E----EGKKR---FCKNCD---ALI--MGQKVHPIGFRLG--VI-KTWDSKWFE------H-K N--YAQWLHEDIRIREFV--KKSLN-----HAGVSKVEIERAA-N-KVKVNVHTARPGIVIGKRGAGIETVKKDLQQFVF LNIVEVRK---AETDAQLVAENIATQLERRIAFRRAMKKALQTAMKF-GAKGIRVACSGRLGGAEMARYEWYREGRVPL- -HTLRADIDYGFAEAKTTYGKIGCKVWVCMPVNDPVGDMLTRLRNASRARHDKVVI-PHSKLKLEIIKVLKDEGYIGEFV VHE----Q-TVQNKRTVFPEISVQLKYG---PDR-------A---PAITGIRRVSKPGLRRYAAAREIPQVLGGLGISIL STSRGIMVDSEARKQKVGGELLCTVYMATQKIRIRLKAYDSKLLDQSAGEIVETAKRTGAKVAGPIPLPTRINKFTVLRS PHVDKKSR-EQFEIRTHKRLLDILEPTQQTLDALMKLDLSAGVDVEIKSPKTRVGIVTSNKMQKTVVVTVQRRAPHPKYG KIMSLREKYKAHVED--HDINEGDRVRIAETKPASKDKRWRVVEVLEKS------------------------------- -MARSI-KKGPFVDD-FLVKKIEDMIK---TNKKA----VVKTWSRRSTILPEFVGHTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRTFGGHS------A--EKKVAKAPGK-------- >DELTA_Pelobacter_carbinolicus_DSM_2380 Concatenation of 2 sequences MAIKKYKPTSAGRRHMTSADFAD-ITAA------------KP-EKSLVEKLNKSGGRNNAGRITKRH-TGGGHKRK---- YRVIDFR-R--EK-KEIPAKIASIEYDPNRSARIALACYA-DGEKRYILAPLGLKVGDVVIASE-Q-AD-IKPGNALSIR SIPLGTWVHNIELKIGKGGQLARSAGTYAMIAAK--EGKYAQLRLPSGEVRLVLQDCCATVGQVGNVQHENVKIGKAGRN -RWL-----GKR-P-QSRGVAMNPVDHPHGGGEGKS-S--GGRH-PVTP---WGVPTKGYKTR-VNKR-TD-R-FIVRRK --------------------------------MTK---G-ILGKKLGMTQVFA-VDGK---------CIPVTVVEAGPCV VLQKK----TEE----K--DGY--NALQLGF-------GA--KVNK----------PAMGHFK----------------- ---SG-KGAFEFLREVEC--------ENIDDH-----AV---GD-EITC--DGF-FATGDVIDVTGTSKGKGFQGVIKRW NFAG-GRASHGS-MFHRR-PGGIGAS-AWPS-RVFKGKKMAGQMGNKRVTTQGLEVVDVRPEKS---------------- ----------LVLIKGA-VPGPVNGLLLIR-MAKIAVYD-INRNQV-SERELSDEVF----NA-EV-KEYLIHDMVRYQL AARRQGTSAAKNRSA--------VA-GGGKKPY---------RQKGTGNAR--------QGT---IR-AP----HF---- VGGGAAFGPS-P-RDFSFKLNRKVKKAALRSALSARFKEE----------------R-VAVLNDF----QLE-K------ --IGTKLVV--VGEDN--R---NLELSARNLPHVK-V---------------LKAEGVNVYDLMNHRN----LVVTEGAV EQLEARLKEVYSTEI----APALVKRLQLKNVMEVPRVEKVVLNMGLG-EAIQNIKVLESAVEELTRICGQKPVVTKAKK SIAQFKLREGMPIGCMVTLRRDKAYEFLDRLINVALPRVRDFKGVSK-KGFDGRGNYTLGIREQLIFPEID-----LEKV DKVKGLNVTIVTT-----------------------AKNDEEGYALMEAIGMPFMSRIG-K--KPIDIPKGVTVS-L--- -A-G--D-TVTVKGPKGELTRNI--VA-G--IRLETAG-DQ--ILV------QCEKEGKQEG-AYRGLVRALVANMVEGV TNGFERVLEINGVGY--RAEVKG-SA--LNLS--LGYSHPIEYAL-P-K-GISAEVE--K-QTKIIVRG-IDKELVGATA AKIRSFR------KPEPY---KGKGVKYAEERIVRKAGK----------MIQMQTMLDVADNSGARKLCCIKVLG-SKRK Y--AGLGDIIICSVKEALPN-S-------RVKKGDVVRAVIVRTAKEVPRPDGSAIRFDKNSAVVVN-QAGE-PIGTRIF GPVARELR-AQRYMKIVSLAPEVLMD-L--SNLRPAIGS-TKNRKRIG-RGPGSGN-GKTAGKGHKGQNARSGGG-V--- -KPGF-E-GGQMPLQRRLPK-RG--FKSVNLRDLVDIEALGQN-GLVSIK---------ILG--DGD-L-D-K-A-LTV- KAHKFSQSAIAKIEAAGGKA-K---QFK--GRM---KGVA-YRGSDLNFG----------DYGLKAV--ECGWLSSRQIE SARRAMTRHV------KRGGKIWIRIFPDKSLTKKPAETRMGKGK---------GSPDSWVAVIKP-GMMLYEM--QG-- VDKEVACEALRLAAHKLPMKTKI-VRRQARLKRQVRVRRKL---RGTPEMPRLCVFRSAKHIYAQIIED---V--TGKTL VSASTV-NSDV-VEGL----ENT-GNVEAAKAVGKAIAQK--ALGMD-IKNVVFDRNGFLYH--GRVKTLAEAAREAGLS F--------------------------------------------------------------ME-AKAKLRYVRLSPRK TRLVVDMVRGKKVQEALNILRFS---------------------------------PQKAASIVYQLVGSAVAN----A- EQKG-VADVDRLFIESISVDQGPVLKRFMPRAQGRATRIRKPTSHITVVLNEKMHVKKDDMVMVIAGK------EK-GKT GKIMRVLPGKG--RVV--VENLNVVKRHTR----PN--RV-NTQ-GGIVEKEAPLDASNVA-LVCSAC-------NK--P --TRTGVRV---LE--------DGKTR---FCKKCN---ETL--MGQKVHPIGFRLG--VV-KTWSSRWYA------E-G E--YSQLLHEDIKLRNYL--KKRLY-----HAGVAKIELERAA-S-KAKINVYAARPGIIIGKKGAEVEALKKDLARLVF INIQEVRK---PEIDAQLVAENVATQLERRVAFRRAMKKSVSMALKF-GAQGIKITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGVKVLIFMAMTDPIADMLTRIRNAGLAKHQKCDM-PASNVKLAIVNVLKELGYIKNFK QIS----D---D----KQGILRIYLKFD---NEN-------K---HIIHAIDRVSTPGCRVYVGKDEIPVVKNGLGNAIL STSKGVMHDAAAREAQLGGEVLCSVWMQSQKIRIRLKAYDHKLLDLSVNEIVDTAKRTGARVAGPIPLPTIINKYCVLRG PHVDKKSR-EQFEMRTHKRLLDIVEPTQQTVDALMKLDLSAGVDVEIKLRKTRVGVVISDKMDKTVVVKVDQMVKHPIYK KYIKRRVTFKAHDEE--NRCNVGDKVSVVETRPLSRDKRWRVREILEKN------------------------------- -MARSI-KKGPYVEE-SLLRKADFEGG---AGSKK----VIKTWSRRSTIIPEFVGYTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRTYYGHG------A---DK----KGK------R- >DELTA_Pelobacter_propionicus_DSM_2379 Concatenation of 2 sequences MGIKIYKPTSPGRRHQTCSSFEE-ITTS------------TP-EKSLLIKLKKSGGRNALGRVTSRH-QGGGHKQK---- YRIIDFR-R--DK-ISIPAKVASIEYDPYRSARIALLHYV-DGEKRYILAPLDLKVGDTVLSGP-E-AD-IKPGNALPLK AIPLGTIIHNVELKLGKGAQLARSAGTFAQLMAK--EGRYSQVKLPSGEVRMVLQDCYATIGQVGNVDHEKVSLGKAGRA -RWL-----GKR-P-KVRGVAMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGIPTKGYKTR-TNKS-TD-R-FIVKKR --------------------------------MKK---G-IIGKKIGMTQIFT-EDGT---------RVPVTVIQAGPCV VTQKK----TAS----I--DGY--SAVQVGF-------DS--TASK----------PMLGHCK----------------- ---SG-QGVFRYLREFKF--------DAASEM-----NL---GD-VLTV--E-Q-FTAGDFVDVTGTSIGKGFQGVIKRY NFRG-GRASHGS-RFHRA-PGSIGAS-ATPS-RVFKNKKMPGQLGNTQVTMQCLQVIRVDADDN---------------- ----------LLLIKGA-IPGHRNNIVLIK-MPSIAVYN-MNRQQV-GELQLADDVF----NA-DV-KEHLMHLALRIQL ANRRAGTVKTKTRSE--------VA-GSGKKPF---------KQKGTGNAR--------QGC---VR-AP----QY---- PGGGVAFGPQ-P-KEYHLSMNKKARKSAICSALSLQCKNN----------------R-ITVMDKL----DFS-S------ --ISTKLII--TDDFS--N---NLQLSCRNVPHVK-L---------------LKHDALNIHDILKYKN----IIFTQGAV QSVEARLKEIYHKDV----MQKLRSDFSYANIMEVPKIVKVVVNMGLG-EAIQNVKILDSAAAELAAITGQKTVITKAKK SIATFKLRQGMPIGCMVTLRRAKMYEFLDRLMNVSLPRVRDFKGVSA-KAFDGKGNYTLGIKEQLIFPEIN-----YDAV DKIKGMNITIVTS-----------------------AKTDEEGRALLKYLGMPFMSRIG-K--LPIDISKDVKLAFS--- -D-----SILSVQGPLGKLSRRIMPC-----VNLEITD-SC--IIV---MR-N--DESGTAR-SAHGLTRTLVSNMVNGV TKGFQKSLEINGVGY--RAEVKG-SE--LVLS--LGYSHPVVFTI-P-A-GVTIEVD--K-LTKVVVKG-FDKELVGETA AKIRSFR------PPEPY---KGKGVKYADETILRKAGK----------MIQMQTILDVADNSGAKKLFCIKVLG-SKRK Y--AGVGDIIVASVREALPN-S-------KVKKGDVVKAVIVRTAKELGRPDGSYIRFDDNSGVVIN-NQKE-PVGTRIF GPVARELR-AKKFMKIISLAPEVLMD-L--NTLKPALGS-VKQGKRIG-RGPGSGH-GKTATKGHKGQKARSGGS-I--- -KAGF-E-GGQMPLQRRLPK-RG--FTPVNLKQLVDTESLVAM-GLVKVK---------ILG--NGD-L-A-K-S-LRV- SASKFSQSAKDKILAAGGTV-K---QMK--GRM---TGKP-CRGISLSFG----------EFGLQAT--ECGWLDSRQIE AARIAMTRYI------KRGGKIWIRIFPDKPLTSKPAETRMGKGK---------GSPDSWVAVIKP-GTILYEM--EG-- VSEEVAREALRLAAHKLPVSTKF-IKLITRIKRKVRVRKKI---VGTAQRPRLNVFKSARHIYAQLIDD---T--AGITL ASCSTL-STSA--ESL----SYT-GNIAAAVHVGKEIAGL--AKEKN-ITAVVFDRNGFLYH--GRIKALADAARESGLL F--------------------------------------------------------------ME-SSAKLTSVRLSPRK TRLVVDLVRGKVIQEALNTLRFL---------------------------------PQPSAKLVSKLLQSAVAN----A- EQKG-VSDVDALYVKTIYVDGGSVLKRFLPRAMGRASKIRKPTSHISVTLSDKTHVRKGETVMVIAGK------DK-NKT GTVMQFLPKKD--GII--VEGLNMVKRHVK----AR--GN-EP--GGIKEKEASIHISNVM-PYCAKC-------AK--P --VRVRLKV---LE--------NGKQR---LCAKCG---NSL--MGQKVNPIGFRLG--VI-KSWDSKWYA------E-A D--YAKLLHEDLKIRAFL--KKRLY-----SSGISKIEIERAA-N-KTKINIYTARPGLIIGKKGSEVETIKKELSNLIF INIIEVRK---PELDAQLVAENVALQLERRIAFRRAMKKSVTSALKF-GAKGIRITCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDYGCAEAKTTYGLIGIKVLIFMSMTDPIADMLTRIRNANMVKHQKVDI-PSSTMKVNIASVLKQEGYIKNYK VIS----D---N----LQGILRVYLKYI---DDK-------D---GVINEIKRISKPGGRVYVKADEVPTVKSGLGVVIL STSKGIITDSAARKAGLGGEIICTVWMQSQKIRIRLKAYDHKLLDVSVTEIVDTAKRTGARVAGPIPLPTVINKYCVLRG PHVDKKSR-DQFEIRTHKRLIDILDPTQQTVDALMKLDLAAGVDVEIKLRRTQNGVVVSDKMDKTVVVKVDRLIKHPVYN KYIKRSAKYKVHDEN--NVCKIGDRVQIIECRPLSKDKRWNLKQISN--------------------------------- -MARSI-KKGPFIDE-HLAKKVLAEGP----NSKK----IIKTWSRRSTITPDFIGLSFAVHNGRKFVPVYVTE-NMVGH KLGEFSPTRTFHGHA------A---DR----KSK-----AKR >DELTA_Sorangium_cellulosum_So_ce_56 Concatenation of 2 sequences MGIRSFKPTSPARRYYSVSDFKE-ITKV------------EP-ERSLLEQQTSTGGRNNNGRITSRF-RGGGHKQR---- YRIIDFR-R--DK-IGVPAKVATIEYDPNRTARIALLHYV-DGEKRYILAPDGLAVGATLLASR-N-AD-IKPGNSLTLR FIPPGTSIHNVEVKKGKGGQLVRSAGVAAQLMAK--DGDYAQVRLPSGEIRKVHLDCRATIGQVSNSEHANISLGKAGRS -RWL-----GRR-P-HNRGVTMNPVDHPMGGGEGRT-S--GGRH-PCSP---WGQLSKGLKTR-NNKR-TD-G-MIVRRR --------------------------------QHP---G-IIGKKIGMTQIFN-ETGE---------VLRCTVVQAG-CV VIGKR----TLE----K--DGY--SALILGL-------GE--RTTK----------PVAGAYK----------------- ---SG-QTPKRIVRELRC------SPEHAAKY-----EI---GT-TLKV--DEI-FEVGQRVDAQGRSRGRGFSGVIRRW SFAG-AVNSHGTHEYFRH-GGSIGTN-MTPG-RTLPGLKMPGHYGDETVSALNLKIAKLLPEDN---------------- ----------LILIEGP-VPGPKNQVVTIR--MKVTVYN-LKREQV-GELDLSDEVF----GT-EV-KEHLFYEVVKAQL ASRRSGTKATKERSA--------VA-GSTKKLY---------RQKGTGRAR--------QGS---IR-AP----HH---- AGGGMAHALE-P-KDWSYRPPRKVRIGALKSALSLFAKEG----------------R-LIVLDSL----EVS-E------ --IKTKLVV--DTAGN--D---KLVKSLRNLENHQ-Y---------------LPPEGVNVYDLLRHDH----LIVSRDAA KALEPRLRTHYRKSV----TAALAKKFGYKNPMMVPRLQKVVINMGLG-AAVQNPKIIDSAVEDMRAISGQKPVVTRARK SIATFKLRENLPIGVMVTLRAERMWEFVDRLIAFSLPRVRDFKGVSP-KGFDGKGNFTMGLREQIIFPEID-----YDKI DVVKGLNISFVTT-----------------------AKTDEEGRALLTELGIPFTSRVG-K--RPIDLPKGVTAT-V--- -N-G--R-KIDVKGPKGQLSRAI-TDK----VDIKLEG-SK--LHV----S-S-VAPGRDAS-RLQGLTRALVAAMVKGV AEGYERTLELKGTGY--RVELKG-TT--LNFA--LGFSHPVTFPV-P-T-GLTATIPADSKGTVLVLTG-ADKELIGQTA ATIRGFR------PPEPY---GGKGVRYRGERVREKAGK----------MIQVSTHLEVADNSGARIVKCIKVLG-SRRK Y--AALGDVIVVSIKEALPG-T-------KVKKGETARAVVVRTAREYQRSDGSYIKFDGNSAVLIN-KEKE-PIGTRIF GPVARELR-AKKFMKIISLAPEVLDI-L--SKLQAPEGA-VTKRLRVG-RGVGSGV-GKTSGRGQKGQKARAGGNIN--- -KKHF-Q-GGQTPIQRRLPK-RG--FRNVNVGDLVDLIALHER-RLVQLK---------ILG--DGE-L-T-K-K-LTV- TAHRFSKGAVEKIEKAGGKA-K---MQK--GNN---RGLA-MTGSDVSFG----------DFALQCV--EPARVTSRQIE AARMAIQRHV------KRAGKLWIRIFPDRPVTKKPLEVRMGGGK---------GAPEEWCALVQP-GRVMYEI--SG-- VSEETAKEAFRLASHKLPMQCKF-LKIVGRERRKLRIRKKV---EGTPERPRLSVFRSSKHIYAQVIDD---V--SGKTL AHASTL-SKDL-KGSL----DED-NKVEAAKKVGALIARI--CKERQ-IDKVVFDRNGYLYH--GRVSALAQAAREAGLD F--------------------------------------------------------------MV-SKASAMFSRIAPRK ARMIADLVRGRDADEAIQLLSFT---------------------------------QKSGAPVLRKIIESAVAN----A- QQA--GADIDALFISKATVDKGPNKRRWRPRAMGRATRITKGVSHIVIEVDEMKRLRVGDLVQVISGK------EE-GKQ GRITKILADED--RVV--VEGLNTVTRHQR----PT--PR-NQE-GGKITKEAPIHASKVM-PVDPAT-------GK--P --TRVKVRV---GE--------DGKKT---RVGKSG---SAI--MGQKTHPYGFRVG--VI-KTWSSKWYE------DGA A--YQKWLHQDIRIKRAI--KQYLY-----NANIAGVEIERAA-N-RAKVIVFTARPGMVIGKGGKGIETLKSGVSSFVF IDVQEVRK---AETNAQLVAENIATQLERRIAFRRAMKKAVSTAMKF-GAKGIRVRCAGRLGGSEMSRVETYREGRVPL- -HTLRADIEFGLAEARTKVGIIGVKVWMF-MMTDPIADMLTRIRNAALARHDRTEV-PASRIKAAVAEILKSEGFIADVR ETE----G---E----GPKKLTIVLKYG---RDR-------Q---SAIDGVRRVSRPGRRVYVRHDRIPRVFSGLGISIL STSRGLMSDRDARRLKMGGELICEVWADTTKIRIRLKAFDHQLLDKSTSDIVETAKRTGAHVAGPIPLPTEIRRYTVLRG PHVDKKSR-EQFEIRTHKRLLDIIEPTQQTLDALMKLDLSAGVDVEIKSRRKLVGKVTSNKMNKTVTVEVIRNALDPVYK KYVRQRERYKAHDET--NQYKVGDRVEITEHRPISRDKRWLVTKLVARP------------------------------- -MPRSI-KKGPFIDG-HLLEKIQAAQA---TNAKK----VIKTWSRRSTILPESVGLTFAVHNGRKFVPVFVTE-NMVGH KLGEFAPTRTFHGHS------G---DK----KAK-VAKGGPG >DELTA_Syntrophobacter_fumaroxidans_MPOB Concatenation of 2 sequences MGIRKVNPTSAGRRFQTYATFEE-LSNV------------EP-EKSLLEPLRRSGGRNASGRVTSWH-RGGGHKRR---- YRIIDFK-R--NK-ENIPATVASIEYDPNRSSHIALLKYA-DGEKRYIIAPVGLSVGDTVLTGA-E-AD-IKPGNCLRLA NMPLGTIIHNVELKPGKGGQLARSAGSSIQLIAK--EGTHAILRLPSSEMRMVPISCKATVGQVGNIDHENLSLGKAGRK -RWL-----GKR-P-HVRGVAMNPVDHPMGGGEGRS-S--GGRH-PCTP---WGVPTKGYRTR-KSKR-SD-K-LIVHRR --------------------------------MIK---A-IVGRKLQMSQIFA-EDGT---------AVPITLIQAGPCT VTQVK----TPE----R--DGY--SALQIGF-------GS--RVNK----------PMKGHLK----------------- ---VG-KGYFEVLREIRM--------ENASDH-----EV---GE-DLAA--D-V-FEIGERIDVIGTTKGKGYAGTIKRW GFQR-GPSGHGS-KNIRE-PGSTGNA-TFPG-RVIKGKKMPGQKGNKRTTVMNLRIIDVRPEEN---------------- ----------LLIVKGA-VPGSQNGIVLIR-MPTVDIFN-TNRDVV-GQLELSDAVF----AV-PL-RPHVLHEVVLYQL AKRRAGTVKTKGRSD--------VA-GGGKKPW---------RQKGTGRAR--------AGT---SR-SP----IW---- RGGGTIHGPQ-P-RDYEMRIPKKVRRLAVKMALSQKLIDR----------------E-LTVLDQL----QLE-Q------ --IKTRLVV--IAQPD--E---KLQKSARNIPNVK-V---------------LRTEGLNVYDLLNHRS----VLLTRETI GKIEARLRETYRNEI----APKLSEQFKYKSPMQIPRLSKIILNMGLG-DAIQNIKILDSAAEELGMISGQKPVITRARQ SIAAFKLRKGMPIGCMVTLRGDRMYEFFDKLVNVALPRVRDFRGVSS-RALDGRGNYTLGIKEHIIFPEID-----YDKI DKIKGMNITIVTT-----------------------AKNDDEARTLLALMGMPFMSRVG-K--LPITIPKGVDVS-L--- -D-E--P-LLTIKGPKGTLARRM-PGD----VEVHLEQ-GA--VLI----R-R--KDENKSR-SLHGLVRALVNNMVHGV SEGFVISLEIQGTGY--RADAQN-NV--LNLS--LGYSHPIQFVL-P-E-GIKGAVD--R-N-TIRLEG-IDKELLGQTA ARIRALR------PAEPY---KGKGIRYAGEHIHRKVGK----------MIQAETQLNAADNSGAKRLYCIKVLG-TRKR Y--ASVGDIIVVSVKEAIPN-A-------KVKKGDVLKAVVVRTQKEVRRPDGSYIKFDDNSAVLIN-QAKE-PIGTRIF GPVARELR-AKQFMKIISLAPEVLMK-L--DDLAPAPGA-KTNRKRLG-RGSGSGL-GKTAGRGHKGQKSRSGGG-T--- -PPWF-E-GGQMPLQRRVPK-RG--FTNVNVGDLVGPDELRKV-GLVKIK---------LLA--DGD-I-A-S-P-LTI- RVHKASDSAVRKIEAAGGRV-K---QQK--GRM---RGTA-FRGSTLSFG----------DFGLKAL--ECGYITSRQIE AARIAITRHV------KRGGKVWIRFFPDKPFTKKPAETRMGKGK---------GSPEGWHAVIKP-GRVLYEI--KG-- VPETIAREALNLAAHKLPIPTRF-VRETARLKRKKRIRKKL---QGAPERPRLTVFRSDKHIYAQIVDD---T--RGSTL VSACTL-SPDY-KEME----ALK-GKVGAAKRVGELIARK--ALEKG-ITKVVFDRNGYIYH--GRVQALADAARQAGLD F--------------------------------------------------------------ME-VRAVSKFLRVSPHK ARLVADLVRGKKVSDALTILKFT---------------------------------PKKSGRFINKTLRSAVAN----A- ENTK-SMDVETLFVKSIFVDKGPQLKRWRPRAMGRATKILKGSSHITIILAESYRIKKNDTVMVVTGK------DK-GKS GKVLRVIYKKD--RAI--VEKLNMIKRHMK----PS--QQ-NRQ-GGILEKESPIHISNLM-LICAKC-------TD--P --TRVGYKV---LD--------DNKVR---FCKKCN---EVIS-LGQKVHPTGFRLG--IL-KSWDSRWFA------T-K D--YAKLVHEDRKIRDYI--KARLY-----HAGIAKVEIERAA-N-KVKIRIFTARPGIVIGKKGAEIETLRRDLERKIL IDIQEVRR---PELDATLVGENISLQLVRRVAFRRAMKRAVSAALKF-GAKGVRVASAGRLGGAEMARREWYREGRVPL- -HTLRADIDYGTAIARTTYGAIGVKVWIFMAVSDPIADFLNRIKNGQKARFDKVDI-PASRMKASLSRILKEEGYIKNFK LIK----D---D----KQGIIRVQIKYG---EHR-------E---GAITGIKRVSRPGCRVYVGHDEIPRVMNGMGIGIV STSKGIMTDRQARKEGIGGELLCSIWMTNQRIRIRLKAYDHKLLDQSTSEIVMTAKKTGARVAGPIPLPTKIHRYTVLRS PHVDKKSR-EQFEIRVHKRLIDILEPTQQTVDSLMKLDLSAGVDVEIKLRKTRVGRVLSNKMDKTVVVVVERLIHHPQYH KFIRRQNKFKAHDAQ--NACRVGDRVIIEESRPISKDKRWVVVQVLDKA------------------------------- -MPRSL-KKGPFVDG-HLFEKIYKAKE---TGDRK----VIKTWSRRSTIVPEFVGITVAVHNGKKFIPVFITE-NMVGH KLGEFAPTRTFYGHA------G---DK----KSK---VKGKK >DELTA_Syntrophus_aciditrophicus_SB Concatenation of 2 sequences MAIRKYKPTSPGRRYQTCSTFEE-VTTD------------QP-QKSLLGTIKKTGGRNNFGRITSRH-VGGGHKRR---- YRFIDFK-R--EK-LDVPGKIASIEYDPNRSARIALVSYE-DGEKRYIIAPAKVAVGEKIVSGE-R-AD-IKAGNAMPLR NIPVGSLIHNIELKVGKGGQLIRSAGTYGQLMAK--EGSYAQVRLPSGEMRKIFIDCRATIGQVGNNEHENISVGKAGRT -RWA-----GKR-P-KVRGVVMNPVDHPMGGGEGRS-S--GGRH-PCTP---WGVPTKGHKTR-SNKS-TD-K-YIVKRR --------------------------------KKM-----IIGRKIGMTQVFA-EDGA---------AIPVTAIEVEPSV ITQKK----TVE----K--DGY--DAIQLGY-------GR--IATK----------PLQGHFK----------------- ---AD-KGCFRILKEMRC--------DQIQEY-----EL---GQ-EITL--D-I-FESGEMVDITGTTKGKGFAGVIKRH GFRG-GRSSHGS-MFHRA-PGSIGAS-AYPS-RVFKGKKLPGQMGNKQKTVKNLMIWSLRPERN---------------- ----------LILIRGA-VPGARNGYLFIKKMLVAEVFD-INKNKV-SEIELNDAVF----GA-EV-NDAVIYDVVRMQM ASRRFGTAATKGRSD--------VS-GGGKKPW---------RQKGTGRAR--------SGT---SR-SP----IW---- RGGGIVFGPV-P-RDYKYNVPKKVRKNALRSVLSLKYQGQ----------------K-LVVLKDF----PLD-E------ --IKTKLFV--TEERN--E---FLEKSSRNIAGIK-M---------------VRSEGLNVYDVLNHEH----LVIIEPAV KKLEARLKDYYKKEV----IPALISEFGYKNPMQVPVMKKIVVNMGLG-EAIQNVKILDSAAGELEMITGQKVVITKAKR SIATFKLRKGMSIGCRVTLRRERMYEFLDRFINVALPRIRDFRGVSP-NTFDGRGNYSIGVKEQIIFPEIE-----YDKI EKIRGMNIAIVTS-----------------------ANTDEEARALLKFMGVPFMSRIG-K--KPIELPANVTCE-R--- -T-G-N--AIKVAGPRGELTTII--PE-K--VEVVMDQ-TK--VLV---KR-H--SDSREDR-SYHGLVRTLIQNMITGV STGYEKSLEIVGVGF--KAEAEG-RN--LKLT--IGYSSPIIYAV-P-E-GIDLKIE--K-ATNIILSG-IDKEKVGKVA AEIRRIK------KPEPY---KGKGIKYANEQVRRKVGKLLGKSGWSRIMIQMQTVLNVADNSGAKKVACIKVLG-SKRR Y--AGVGDVIVVAVKEAMPN-S-------KVKKGDVMKAVIVRTAKEVRRQDGSYLKFDDNSAVLIS-NQME-PIGTRIF GPVARELR-ARQFMKIISLAPEVLMD-L--SQLRPPEGS-RKKRKRIG-RGSGSGH-GGTSCKGHKGQNARSGGG-V--- -RDGF-E-GGQMPLSRRLPK-RG--FRSLNVEKLIDEHRLKES-GMVKIK---------ILG--KGE-I-D-H-P-LTV- KIKMISQGAKAKIEAAGGSV-K---LQR--GRR---TGTA-TRGSKISFG----------EYGLQAE--ECGWITARQIE AARIAITRHV------RRGGKIWIRIFPHKSITKKPAETRMGKGK---------GAPEEWVAVVKP-GTVLYEM--QG-- VSKEVAREAFRLASHKLPIGTRF-LVQKIRDKRKARVRAKI---SGSTERPRLSVFRSSKHIYVQAVAD---N--EGKTI AHSSTI-SDDV-KSKI----TDV-KKVEAAKEVGRSISRK--LRDMG-IQEVVFDRGSYLYH--GRVKALADGAREEGLK F--------------------------------------------------------------ME-AKATAKYIRISPQK ARLVVDLIRGKKVDDAREILNYS---------------------------------RKRSGQIVGKVLKSAFAN----A- VQNP-NIDEKILFVKEIFVDQGPSMKRWRARAQGRAASIKKRMSHITVILDELKHLKKGDFVKVISGR------EK-GKT GKVLTVISEKN--RVV--IEKMNMVKRHQK----AN--AM-GK--GGIVEKEGPIHASNVM-MMCGKC-------NK--E --TRVGIKK---LE--------DGKVR---ICKKCN---DIL--MGQKVNPIGLRLG--IN-KNWNSRWYA------D-K S--YRSMLYEDLKIRGYL--KKKLY-----HAGISHIDIERAV-N-KAKVNIYAARPGIIIGKKGAEIEKLKKELENVII INILEVRK---PEIDAQLVAENIATQLERRVAFRRAMKKCVLTALKF-GAKGIRVSCSGRLGGAEMSRTEWYREGRVPL- -HTLRADIDSGFTEAKTAYGQIGIKVLIFMGMTDPIADMLTRIRNANRVHFKSVDV-VYSGVNVNIAKVLKKTGYIGGYD VKK----D-E-K----GHDVLKVYLKYP---DSK-------R---TIINDIQRVSKPGRRVYVKGDEIPKVLNGYGVAII STSKGVITDKEAREKSVGGEVLCKVWMKDQKIRIRLKAYDYKLLDRSVEEIVETARRTGARIAGPVPLPTEINKYCVNRS PHVDKKSR-EQFEIRTHKRLIDIIEPTQSTVDALMKLDLSAGVDVEIKANRTIKGVVVSNKMDKTIVIRAERLVKHPVFH KYTRKHVKYMVHDEK--NECKVGDTVIVMESRPLSRLKRWRMLRIVAKA------------------------------- -MARSI-KKGPFVDE-KLFDKVQKAVA---SGNKS----VIKTWSRRSTITPDLIGHTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRIFFSHA------G---DR----KSK-----VRK >EPSI_Arcobacter_butzleri_RM4018 Concatenation of 2 sequences MAIKKFRPITPARRFMSVMDTSD-ITS-------------KPTVRSLLVKVKASAGRNNNGRITSRH-KEAGAKKL---- YRIIDFK-R--NK-FGIEGTVATVEYDPYRNCRICLVSYL-DGDKRYIIQPSGLKVGDKVQAAESG-LD-ILPGNAMQLS NIPVGTMVHNIELKPGKGAQIARAAGGYAQIMGR--EDKYVILRLPSGEMRKILGVCMATVGVVGNEDYTNMVVGKAGRS -RHL-----GIR-P-QTRGSAMNPIDHPHGGGEGKT-N--SGRH-PVTP---WGMPTKGYKTR-K-KKASD-K-LIISKR --------------------------------------MEFIVQKIGMSRTVSVP------------STAVTLLRVLDTK VCEVT--------------EGV--ALVSYSN-------GK---FNK----------AIEGQQK----------------- ------FNLSKEFNRFAT--------ITVANA-----EA---GDLDVSG------LGEAKVVKSTFKTKGRGFSGAVKRW NFAG-GRASHGHRMGKRT--GSIGNC-EWPG-RVQPGKKMPGQYGNTNVSVKN-EIISFDAETG---------------- ----------ILVLKGS-VSGANGSLGKIK-MSKAIVLN-EKFENN-GEVVLPASYE-------EI-NSHNLYLYVKSYL ASLRANTARAKTRAE--------VS-GGGKKPK---------AQKGSGAAR--------WGS---KR-SP----LF---- VGGGQAFGPT-K-RNYNQKVNKKQKALALKYALNAQANNG----------------S-LFVVDSL----KIE-S------ --GKTKLIV--CDVID--E---KTYLAFRNIKNCY-M---------------VEKQEVNAYLIAVYHS----VLIEKSVL DALTSRLFEKYKSEI----KPVLETEFP-KNKTLTAKLEKVVISVGAG-EAMKDSKLIQNIEDTISLIAGQKAVKVIAKK SVAGFKVREGMPVGVKVTLRGEQMYHFLDKLCNVALPRVKDFRGLNK-NGFDGRGNFNFGLDEQLMFPEVV-----YDNI IKTHGMNISIATS-----------------------ATNDAEAYRLLELVGIPFMSRIG-K--KPITIPAGIEVT-V--- -N-G--T-LISVKKGNNVSTVET--HG-R--VGIEVAN-GQ--VIL----T-R--NGDKESS-AFWGTYRALTANAINGL HEGFTKSLEINGVGY--RATLKG-DI--LELA--LGYSHPINYEI-P-K-GLEITVE--K-NI-VSVKG-ADKQQVGQAA AIIRGFR------KPEPY---KGKGVKYTDEKIIRKAGK----------MIQSFTRLNVADNTGAKEIMCIKVLG-SKRR Y--ATVGDVIVASVKKALPT-G-------KIKKGQVVKAVVVRTHKEVQRENGSLIRFDDNAAVILD-AKRE-PVGTRIF GPVAREVR-YSGFMKIVSLAPEVLMV-L--DNLQPAAGS-TKNVKRIG-RGQGSGT-GKTAGKGNKGQKARSGYN-V--- -KRGF-E-GGQQPLARRLPK-IG--FTSINVDRIITLDSIKSV-YKLSVK---------LIG------------T----- TAKNLVAKIKDENVTTTGK--K---MMK--GRN---RGMA-HRGNSLAYG----------DFGIKAV--EHGRIDSRQIE ASRIAMTRKV------KRQAKVWIMVFPDKPLTAKPLETRMGKGK---------GSVDKWVMNIKP-GRICFEM--AG-- VGEELAREALALAMHKLPFKTKI-VKVALRIKRKKRVRGNI---FGTAEKPRVSIFKSNRYVSAQAIND---V--EGVTL AAVS---SKTM---------GLN-VNKENAGKVAAQLAEN--LKAAG-IESVVYDRNGYLYH--GVVAAFADGLRANGIK L---------------------------------------------------------------M-AKAILKFIRVSPIK ARLIAREVQGMNAEYAIASLQFT---------------------------------PNKAAGIISKVIASAVAN----A- -----GLDPVDAVITSARVDKGPVLKRFTPRARGSASPKHKPTAHIMIEVAAKLKIKKGDTVKIIAGD------DK-GKT GEVLAVLPKEK--KVI--VKDCKVAKKTVK----PD--QEKNPE-GGFVNKEMPIDISNVA------------------- ------------------------KVE--------G---E----MGQKVNPIGLRLG--IN-RNWESRWFP------KFE T--MPANVAEDDKIRKYV--KKELY-----YAGIAQTVVERTA-K-KVRVTVVAARPGIIIGKKGADVEKLKDALSKLIA VNIKEERK---PQISAQLSAENVAQQLERRVAFRRAMKRVMQNALKG-GAKGIKVSVSGRLGGAEMARTEWYLEGRVPL- -HTLRARIDYGFAEAHTTYGCIGIKVWIF-MMNDIIADALTRIRNAAMRRLEVATL-LHSNTVVGVLNVLLQKEYIAGFK VID--GQN--------NKKTIQVELKYD---DNE-------K---SVINEITRVSKPGRRVYKSASEIKNFKNGYGTIIV STNKGVIANDEAYAANVGGEVLCTVW--MEKIRLKLKAYDHRVLDRSVASIVEAVKRTGADLRGPIPLPTKIRRYTVIKG PHVNKDSR-EQFEIRVHSRIIDIIVATPETVDSLMKLDLAPEVDVEVRSKREIQGVVVKKSGDKTASVLVTRSVLHPKYH KTVKRFKKYLIHDEK--NELNVGDSVIAIECRPLSKTKSFRLKTIVATG------------------------------- -MARSI-KKGPFVDA-HLMKKVLSANS---ANDKK----PIKTWSRRSTVLPEMIGITFNVHNGRNFVPVLITE-NHVGY KLGEFAPTRTFKGHK------G--SVQ----RKA-------- >EPSI_Campylobacter_concisus_13826 Concatenation of 2 sequences MAIKSYKPYTPSRRYMTGLSSED-ITA-------------KPSVRSLLVKLPATGGRNNNGRITSRH-KEAGAKKL---- YRIIDFK-R--RK-FGIEGKVEAIEYDPNRNCRIALIAYK-DGEKRYIIRPNGLNVGDVIASGS---LD-IKPGNAMKLR FIPVGTIVHNVELKPGKGAQIARSAGGYAQLMGK--EEKYVILRMPSGEMRQVLAECMASIGVVGNEDWANITIGKAGRN -RYR-----GIR-P-QTRGSAMNPVDHPHGGGEGKK----NSGRHPVTP---WGKPTKGAKTR-RKKA-SD-K-LIISRR --------------------------------------MEYIVEKIGMSRTI---ATK---------STPVTLLKLVEAK VCEID--------------EN---KRAIVAY-------AH---NNK----------AIAGQQK----------------- ------YNLTAEFNKFAT--------LEVANS-----EV---GNLDFTP------LNEAKILKVSFNSKGRGYQGVVKRH GFGG-GPKSHGS-RFHRR-HGSIGNC-EWPG-RVQPGMKMAGHMGNEKVTVKN-ELISFDAQNG---------------- ----------IVVVKGC-VPGHNGAMGKIR-MSKIHVLN-DKFENS-GELELPASYA-------EV-NPHNLYLYVKSYL AGIRANSAHTKSRAF--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPT-NEKNYFQKVNKKQKRLALEYALAVKAQDG----------------K-IFAVDSI----SIE-S------ --GKTKLIV--KDLLD--D---KTLLAFRNLANCY-V---------------VDANEVNAYLVSTFSS----VIIEKAAL KTITSRLKDKFNETI----KPALVKEFDIKNPMLIPALEKIVISVGAG-DSAKDQKVLQNMADTISLIAGQKAVITDAKK SVAGFKVREGFPVGIKVTLRKEQMYAFLDKLISVALPRVKDFRGLPK-NGFDGRGNYNFGLSEQLMFPEVE-----YDKI LRTHGMNITIATT-----------------------AKNDKEAFKLLELFGVPFMSRIG-K--QPIAIPSGVDVS-V--- -E-N-----NVLKFKKGNHLKELDTKG-H--VDVKIEN-GH--IVF----A-P-KGEDRQSR-AYWGTYRALANNIVTGI THGFTRQLEINGVGY--KAAAKG-KI--LELS--LGFSHLINYEL-P-A-GVEASVD--K-N-VITIKG-DDKQVVGQVA AQVRGFR------PPEPY---KGKGVKYLEERIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKVLG-SKRR Y--ATLGDIIVCSVKKALPN-G-------KIKKGQVVKAVVVRTKREVQRDNGSLIRFDENAAVILD-SKKE-PVGTRIF GPVGREVR-YANFMKIVSLAPEVLMA-L--EKLTPAAGS-THATKRIG-RGQGSGN-GKTAGKGNKGQRARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FASINVEKIISIATIASV-HKISIK---------LIG------A----------- SAKALASKIKDENVSVSGTK-K---QMK--GRN---RGYA-TRGASLATG----------EFALKAV--EAGRVNSRQIE AARQALTRHV------KRQAKIWIRVFPDKPLTKKPLQTRMGKGK---------AGVEEWVMNIKP-GRIIFEM--AG-- VDEELAREALTLALHKLPFKSKF-VKIALRIKRKRRIRGKI---SGVATCPRVSIFKSNRTLYVQAIDD---V--TATTL AAVD---GRKL---------GIK-ANKEGAVTLAKEFAKA--LKAKK-IDVAIFDRNGYLYH--GVIAAFAEALRENGIK L------------------------------------------------------------------------------- ----------MNAELALASLQFM---------------------------------PNRGAKFIANAISSAVAN----G- -----GFEPEEVVVTSCRVDAGPVLKRFRPRARGTASKIRKPTSHVMVEVSKKFKVKKGDTVKIIAGD------DK-GKT GKILAVLAKKG--QVI--VEGCKVAKKAIK----PS--EK-TPN-GGHVNKEMPIDISNVA------------------- ------------------------KVE--------G--------MGQKVNPIGLRLG--IN-RNWESRWFP------TKQ S--LPENIGEDYKIRAFL--KKKLY-----YAGISQILIERTA-K-KLRVTVVAARPGIIIGKKGQDVENLKNEVSKLVN VNIKEERK---AQASAQLAAENVAMQLEKRVAFRRAMKKVIQGAQKS-GAKGIKISVAGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGVAEAHTTYGNIGIKVWIF-MLNDLISDGLTRIRNASMRRLETAKL-LHSKVVEATLSILAAKGYVESYN VIE----E---G----NKKFINVVLKYD---EYG-------R---SVINELKRVSKPGRRVYQGKDDIKRFKNGYGTVIV STSKGVMSGIEASKAGVGGEVLCTVWKHMERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADVRGPVPMPTKIKRYTVLKS PHINKDSR-EQFEMRIHARMLDIVAATPETVDSLTKLDLAPEVNVEVRAKREIQGVVLQKAGDKTATILVERRVMHPRYH KFVKRFKKYLVHDEK--NETRAGDTVVAVECRPLSARKNFRLKAVLAKG------------------------------- -MARSL-KKGPFVDD-HVMKKVIAAKN---ANDNK----PIKTWSRRSTIVPEMIGLTFNVHNGKSFIPVYVTE-NHIGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Campylobacter_curvus_52592 Concatenation of 2 sequences MAIKSYKPYTPSRRYMTGLSSED-ITA-------------KPSVRSLLVKIPASGGRNNNGRITSRH-KEAGAKKL---- YRIIDFK-R--KK-FGIEGRVEAIEYDPNRNCRIALISYK-DGEKRYIIRPNGLNVGDVIASGA---LD-IKPGNAMKLK FIPVGTIVHNIELKPGKGAQIARSAGGYAQLMGK--EEKYVIVRMPSGEMRQILAECMASIGVVGNEDWANITIGKAGRN -RYR-----GIR-P-QTRGSAMNPVDHPHGGGEGKK-N--SGRH-PVTP---WGKPTKGAKTR-RKKA-SD-K-LIISRR --------------------------------------MEYIVEKIGMSRTISTQ------------STPVTLLKLVEAK VCEID--------------EN---KRAIVAY-------AH---NNK----------TIAGQQK----------------- ------YNLTAEFNKFAT--------LEVANS-----EV---GNLDFTP------LSEAKILKVSFNSKGRGYQGVVKRH GFSG-GPKSHGS-RFHRR-HGSIGNC-EWPG-RVQPGMKMAGHMGNEKVTVKN-ELVSFDAENG---------------- ----------IVVVKGC-VPGHNGAMGRIR-MSKILVLN-DKFENS-GELELPASYA-------EV-NPHNLYLYVKSYL AGMRANTAHTKSRAY--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPT-NEKNYFQKVNKKQKRLALECALAQKAEAG----------------K-LFAVDSL----AVE-S------ --GKTKLIV--KDLLD--D---KTLLAFRNMANCY-V---------------VDASEVNAYLVSVFSS----VIVEKAVL QTITGRLKDKFNESI----KPALVKEFDIKNPMLVPALEKIVISVGAG-DFAKDQKVLQNMADTISLIAGQKAVITNAKK SVAGFKVREGFPVGIKVTLRKEQMYAFLDKLISIALPRVKDFRGLPK-NGFDGRGNYNFGLSEQLMFPEVE-----YDKI LRTHGMNITIATT-----------------------AKNDKEAFKLLELFGLPFMSRIG-K--QPIAIPSGVDVS-V--- ---A--N--SVLKFKKGNNTKELDTKG-H--VDVKVEN-GH--IVF----S-P-KGDDRQSR-AYWGTYRALANNIVTGL TSGFTRQLEINGVGY--KAAAKG-KI--LELT--LGFSHLINYEL-P-S-GVEASVD--K-N-IITIKG-DDKQVVGQVA AQVRGFR------PPEPY---KGKGVKYVEERIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKVLG-SKRR Y--ATLGDVIICSVKKALPN-G-------KIKKGQVVKAVVVRTKKEVQRGNGSLIRFDENAAVILD-NKRE-PIGTRIF GPVGREVR-YANFMKIVSLAPEVLMA-L--QNLTPAPGS-THATKRLG-RGQGSGN-GKTAGKGNKGQRARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FTSINVEKIITVATIASV-HKISIK---------LIG------V----------- SAKELASKVKDENVSVSGSK-K---QMK--GRN---RGYA-TRGASLSTG----------EFALKAV--EAGRVNSRQIE AARQALTRHV------KRQAKIWIRVFPDKPLTKKPLQTRMGKGK---------AGVEEWVMNIKP-GRILFEM--AG-- VSEELAREALTLAMHKLPFKSKF-VKLALRIKRKRRIRGKI---SGVATTPRVSIFKSNRTIYVQAIDD---V--TATTI AAAD---GRKL---------GIK-ANKEGAAILAKEFASV--LKAKK-IDTAVFDRNGYLYH--GVIAAFADALRENGIK L---------------------------------------------------------------M-SKAIIKFVRLSPTK ARLIAREVQGMNAELALASLQFM---------------------------------PNRGAKFIANAISSAVAN----G- -----GFEPEEVVVSSCRVDAGPVLKRFRPRARGTASKIRKPTSHVMVEVSKKFQVKKGDLVKIIAGD------DK-GKT GKILSVLAKKS--QVI--VEGCKVAKKAIK----PS--EK-IPN-GGHINKEMPIHISNVA------------------- ------------------------KVE------E----------MGQKVNPIGLRLG--IN-RNWESRWFP------T-K A-SLPENIGEDYKIRAFL--KKKLY-----YAGISQILIERTA-K-KLRVTVVAARPGIIIGKKGQDVENLKNDVSKLVN VNIKEERK---AQASAQLAAENVAMQLEKRVAFRRAMKKVIQGAQKS-GAKGIKISVAGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGVAEAHTTYGNIGIKVWIF------------------MRKLETAKL-LHSKVVEATLSILAAKGYVESYN VVE----E---N----NKKFINVVLKYD---DHG-------R---SVINELKRVSKPGRRVYQGKDDIKRFKNGYGTVIV STSKGVMSGIEASKVGVGGEVLCTVWKTMERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADVRGPVPMPTKIKRYTVLKS PHINKDSR-EQFEMRIHARMLDIVAATPETVDSLTKLDLAPEVNVEVRAKREIQGVVLQKAGDKTATILVERRVMHPRYH KFVKRFKKYLVHDEK--NETNAGDTIVAVECRPLSARKSFRLKAIVAKG------------------------------- -MARSL-KKGPFVDD-HVMKKVVAAKA---SNDNK----PIKTWSRRSTIVPEMIGLTFNVHNGKSFIPVYVTE-NHIGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Campylobacter_fetus_fetus_82-40 Concatenation of 2 sequences MAIKSFKPYTPSRRFMTGLSSED-ITA-------------KPSVRSLLVKIPATAGRNHNGRITSRH-KEAGAKKL---- YRIIDFK-R--KK-FGIPGKVETIEYDPNRNCRIALISYS-DGEKRYIIRPSGLNVGDVISSAESG-LD-IKPGNAMKLK SIPVGTIVHNIELKPGKGAQMARSAGGYAQLMGK--EEKYVILRLPSGEMRQVLAECMATVGVVGNEDWANVTIGKAGRN -RYR-----GIR-P-QTRGSAMNPVDHPHGGGEGKK-N--SGRH-PVTP---WGKPTKGAKTR-R-KKASD-R-LIISRR --------------------------------------MEYIVEKIGMSRTV---SAP---------STPVTLLRLVPAK VCELG--------------EG---GKAIVAY-------AH---DNK----------AIKGQQK----------------- ---YGLSSEFNSFATLSV-----------ANS-----EA---GDLDVNP------LNEAKVLKVSFNTKGRGFQGVIKRH GFSG-GPASHGS-RFHRR-PGSIGNC-EWPG-RVQPGRKMAGHYGNEKTTVKN-EVVSFDSANG---------------- ----------ILVLKGS-VPGFNGAMGRVR-MSKIAVLN-EKFEKT-SEIELPASYA-------EV-NSHNLYLYVKSYL AGIRANSAHTKGRSD--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPK-NNRNYDQKVNKKQKRLALEFALNDKVANG----------------K-FFAVDSI----EIS-S------ --GKTKLII--KNELD--A---KTLLAFRNLANCY-V---------------IDASEVNAYLVSVYSA----VIAEKAAL QSIVMRLKAKYNESI----KPALTKEFDIKNPMLIPAIEKIVISVGAG-EGAKDQKLLQNMADTISLIAGQKAVVTNAKK SVAGFKVREGYPVGIKVTLRKEQMYTFLDKLVSVALPRVKDFRGLPR-DGFDGRGNYNFGLNEQLMFPEVV-----YDQI LRTHGMNITIVTT-----------------------AGDDKQAFKLLELFGIPFMSRIG-K--QPISIPNGLDVS-L--- -K-G--S-VLVFKKGNNTKELDT--KG-N--VNIEVKD-GN--IIF----T-S--KGDRQSR-AYWGTYRALANNVVVGL TTGFTKQLEINGVGY--KAAAKG-KV--LELA--LGFSHPINYEL-P-E-GIEISVE--K-NI-ITIKG-SDKQVVGQVA AEVRGFR------PPEPY---KGKGVKYAEERIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKVLG-SKRR Y--ASLGDIIVCSVKKALPN-G-------KIKKGQVVKAVVVRTKKEVQRANGSLIRFDENAAVILD-NKKE-PVGTRIF GPVGREVR-YANFMKIVSLAPEVLMG-L--ENLQKANGS-TRNTKRIG-RGQGSGW-GKTATKGGKGQTARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FASINVDKNITLDSLKTV-HKFSVK---------LIG--AGA-------K----- --DLASKIKDENITVTGNN--K---MMK--GRN---RGYA-TRGVDLALG----------EFGLKAV--EAGRVNSRQIE SARQAYTRHV------KRQAKTWIRVFPDKPITKKPLETRMGKGK---------GGVEEWVMNIKP-GRIIFEM--SG-- VSEELAREALTLAMHKLPFKTKF-VKISLRIKRKRRIRAKI---SGTPSCPRISIFKSNRTIYVQAIED---I--NATTL CASD---GRKL---------GIK-ANKSGAAVLAKDIAGK--LSAKG-INEAVFDRNGYLYH--GVVAAFAEALRENGIK L---------------------------------------------------------------M-SRAIIKFIRLSPTK ARLIADEVQGMNAELALASLSFM---------------------------------PNRGAKYIASAISSAVAN----G- -----GFEPEEVVVKSCRVDAGPVLKRFRPRARGSASRIRKPTSHILVEVSKKYKIKKGDEVKVIAGD------DK-GKV AKVIAVLPKKG--QVI--VEGVKVAKKAVK----PT--EK-NPN-GGFISKEMPIDISNVA------------------- ------------------------KVE--------G--------MGQKVNPIGLRLG--IN-RNWESRWFP------SKA T--LPENIGEDYKIRKFL--KTKLY-----YAGVSQILVERTA-K-KLRVTVVAARPGIIIGKKGGEIENLRSEVTKLIA INIKEERK---AGSSAQLAAENVAMQLERRVAFRRAMKKVIQGAQKA-GAKGIKVSVAGRLGGAEMARTEWYLEGRVPL- -HTLRARIDYGFAEAHTTYGNIGVKVWIF-MINDLISDGLTRIRNASMRRLDTTKL-LHSNVVEATLKILANKSYIESYN VVE----E---G----NKKFINVVLKYD---ERG-------R---SVINELKRVSKPGRRVYQGRDEIKRFKNGYGTIIV STSKGVLSNDEAHKAGVGGEVLCTVW--MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADVRGPVPMPTKIKRYTVLKS PHVNKDSR-EQFEMRIHARMLDIVAATPDTVDSLTKLDLAPEVNVEVRAKRQIQGVVVAKAGDKTATILVERRVMHPRYH KFVKRFKKYLVHDEK--NELKAGDTISAVECRPLSARKSFRLQAVLKTG------------------------------- -MARSL-KKGPFVDD-HVMKKVLAAKA---ANDNK----PIKTWSRRSMIIPEMIGLTFNVHNGKGFIPVYVTE-NHIGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Campylobacter_hominis_ATCC_BAA-381 Concatenation of 2 sequences MAIKSYKPYTKSRRYMTGLSSDD-ITA-------------KASVKSLLVKIPASLGRNNNGRITSRH-KEAGAKKL---- YRIIDFK-R--TK-FGIPAKVEAIEYDPNRNCRIALLNYA-DGEKRYIIQPNELNVGDVISSAESG-LD-IKPGNAMKIK NIPVGTIIHAIELKPGKGAQLARSAGGYAQLMGR--EEKYVILRLPSGEMRKVLGECMATIGVVGNEEWANISLGKAGRN -RYL-----GVR-P-QTRGSAMNPVDHPHGGGEGKT-G--PGRQ-PVTP---WGQPTKGLKTR-H-KKASD-K-LIISRK --------------------------------------MEYIVEKIGMSRTI---DNP---------SIPVTLLRVVNAK ICEVN--------------DG---KAVVAYA------NGK--AFNK----------AIAGIQK----------------- ------YNLSKEFNKFAT--------LCVENA-----EV---GDQSIEI------FNNAKFVKSSFTSKGRGYQGVMKRH GFAG-GPKSHGS-RFHRR-HGSIGNC-EWPG-RVQPGMRMAGHMGNVKVTVKN-EIVKFDAENR---------------- ----------ILVLKGA-VAGFNGAMGRIR-MSKVKVLN-EKLEKA-SELELPANFA-------DV-NPHNLYLYVKSYL ASLRANTANTKGRSE--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPT-NNRNYFQKVNKKQKRLALEFALNEKAQND----------------K-IFAVDSL----EIS-S------ --GKTKLIV--KNELD--S---ATLLAYRNLNNCY-V---------------IDINELNAYLVAVYSA----VIIETSAL QSIVNRLKQLYENSI----KPAIVKEFDIKNSMLIPKLDKIVISVGVG-ESSKDEKILQNMADTISLIAGQKAVITNAKK SIAGFKVREGFPVGIKVTLRKDNMFVFLDKLVSIALPRVKDFRGLSR-DGFDGRGNYNFGLDEQLMFPEVE-----YDKI LKTHGMNITIVTT-----------------------ANSDKEAFKLLELFGVPFMSRIG-K--KPVAIPSGIEVK-V--- -D-G--N-VLKFKKGNAQKELDT--KN-H--VDVKVED-GK--VEF----S-P--KGERQSM-AFWGTYRALAHNIVVGL TDGFSKQLEINGVGY--KAAMKG-KI--LELT--LGYSHLVNYEV-P-D-GIEISVD--K-NV-ITIKG-TDKQQVGQVA AIIRDFR------APEPY---KGKGVKYLEEHIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKILG-SKRR Y--ATVGDIIVCSVKKALPN-G-------KIKRGQVVKAVVVRTKKELHRGNGSLIRFDENAAVVLD-SKKE-LIGTRIF GPVGREVR-YNGFMKIVSLAPEVLMG-L--ENLQKAPGS-TSKTKRIG-RGQGSGW-GKTATKGGKGQTARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FNSINVEKIITFESILSV-HKFPIK---------LIG--AGA-------K----- --ELASKIKDENIKTSGLK--K---MMK--GRN---RGYA-VRGIKLNFG----------DYGIKAV--EAGRINSNQIE AARIAMTRYV------NREAKVWINVFPDKPLTKKPLQTRMGKGK---------TGVEEWVMNIKP-GRIIFEL--TG-- VNEDVARRALELSMHKLPFKTKI-VKISLRIKRKRKIRANI---SGSAVCPRISIFKSNRTIYAQAIDD---T--NSKTL CASSGT-ALKI-----------K-ANKDGAAILAKDFAEK--LKAAK-ISEAIFDRNGYLYH--GVVAAFADALRKNGIK L---------------------------------------------------------------M-SKSTIKFVRLSPTK TRLIAKEIQGMNAEFALATLEFT---------------------------------PNRGAKYIANAILSAVAN----G- -----GFEPNEVIVKSCRVDAGPVLKRFRPRARGTASRIRKPTSHIMVEVSKKFKIKKGDDVKIITGD------DK-GKI GKVLSVLPKKS--QVI--VEGCKIAKKAIK----PS--EK-NPK-GGFINKEMPMDISNVA-LV---------------- ----------------------EG--------------------MGQKVNPIGLRLG--IN-RNWESRWFP------V-K S-AIPENISEDYKIRKFL--KAKLY-----YAGINQILIERTA-K-KLRVTIVAARPGVIIGKKGSEIENLKNEVVALVT INIKEERR---PGSSAQLAAENVAMQLEKRVAFRRAMKKVIQSAQKA-GAKGIKISVAGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEAHTTYGNIGVKVWIF-MLNDLISDGLTRIRNASMRRLDTTKL-LHSNVVESVLKILAEKGYIESYN LIE----E---D----NKKFINVVLKYN---EHG-------K---SAINEITKISKPGRRIYQTKDEIKRFKNGYGTVIV STSKGVMSGIEASKAGVGGEVLCTVW--MQKIRLKLKAYDHRVLDRTVAAIVEAVKRTGADVRGPVPMPTKVKRYTVLKS PHINKDSR-EQFEMKIHGRMLDIVAATPETVDSLTKLDLAPEVNVEVRAKREIHGLVVKKAGDKTATILVERRVMHPRYR KFVKKFKKYLVHDEK--NAVKIGDTISAVECRPLSAKKSFRLKAVLKAG------------------------------- -MARSL-KKGPFVDE-YIIKKVIAAKK---AKDNK----PIKTWSRRSTITPEMIGLTFNVHNGKSFIPVYVTE-HHIGY KLGEFAPTRTFKGHR------GSVQKK----IGK-------- >EPSI_Campylobacter_jejuni_doylei_26997 Concatenation of 2 sequences MAIKTYKPYTPSRRYITGLSSED-ITA-------------KPSVRSLLVKLPAHAGRNSYGRITSRH-KEAGAKKL---- YRIIDFK-R--RK-FGIEGKVEAIEYDPYRNCRIALIAYK-DGEKRYILQPRGLSVGDIVAAAESG-LD-IKPGNAMKLK NIPVGTIVHNVELKPGKGGQMIRSAGAYAQLMGK--EEKYVILRLASGEMRQVLAECMASIGEVGNEEWANITIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKK-N--SGRH-PVTP---WGKPTKGAKTR-C-KKASD-K-LIISRR --------------------------------------MEYIVEKIGMSRTI---TNP---------SIAVTLLRVVNAK VCEVE--------------GGK--ALVAYPK-------GK--ASNK----------CVAGQQK----------------- ---YNLSAEYNRFATLEV-----------ANT-----EA---GDLDETP------LNEAKILKVSFNTKGRGYSGVMKRH NFAG-GPASHGS-RFHRR-HGSIGNR-EWPG-RVQPGMKMAGHYGNTKVTVKN-EVVSYDAENK---------------- ----------ILVVKGA-VPGYNGAMGKIR-MSKVVVLN-DKLEKA-GELDLPSKYA-------EV-NPHNLYLYVKSYL ASLRANTAHTKGRSD--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPT-NERNYFQKVNKKQKRLAFERALADKAAKG----------------A-LFTADSL----AIE-S------ --GKTKLIV--KDLLD--E---KTLLAYRNLANCY-V---------------VDVAEVNAYLVSVFNA----VIMEKSAL ESITMRLKEKYNQSI----KPALVKEFDIKNPMLIPVIEKVVISVGAG-ELAKDQKVLQNVADTISLIAGQKAVITKAKK SVAGFKVREGFPIGVMVTLRKENMYAFLDKLISIALPRVKDFRGLSR-DGFDGRGNYNFGLDEQLMFPEVE-----YDKI LRTHGMNISIVTT-----------------------AQNDKQAQKLLELIGVPFMSRIG-K--QPIAIPAGVEVK-L--- -E-G-----NLLKFKKGNLAKELDTKA-N--VNVEIKD-NN--ILF----S-P-KGEDRQSR-AYWGTYRALAYNIVVGL TQGFSKTLEINGVGY--KAALKG-KV--LELS--LGFSHPINYDI-P-G-GIEIVVD--K-N-TIAVKG-SDKQVVGQVA AQIREFR------PPEPY---KGKGVKYSDERIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKVLG-SKRR Y--ATVGDVIVASVKKALPN-G-------KVKKGQVVKAVIVRTKKEIHRDNGSLIRFDENAAVILD-NKRE-PIGTRIF GPVGREVR-YGGFMKIVSLAPEVL------MNLTKAAGS-THKTKRIG-RGQGSGM-GKTATKGGKGQTARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FTSINVEKIITFESIKSV-HKISIK---------LIG--------A---S----- AKDLVSKIKDENISVTGSK--K---MMK--GRN---RGYA-NRGTEFTFG----------EFALKAT--EAGRINSRQIE AARIALTRFV------KRQGKTWIRVFPDKPLTKKPLETRMGKGK---------GAVEEWVMNIKP-GRIIYEM--AG-- VSEEMAREALTLAMHKLPFKTKF-VKLTLRIKRKKRIRAKI---SGCENFPRISVFKSNRTLYIQAIDD---V--KAVTL AAVD---GRKL---------GVK-ANKEGAKKIAAEFAKT--LKAKK-IEQAVFDRNGYVYH--GVIAVLAESLRENGIR L---------------------------------------------------------------M-SKALIKFIRLSPTK ARLIAREVQGMNAELAMASLKFM---------------------------------PNKGAKYIANAISSAVAN----G- -----GFEANEVIVKSCRVDVAAVLKRFRPRARGSASRIRKPTSHILVEVVKKLKIKKGDNVKVVTGD------DK-GKT GKVLAVYPKTL--KVV--VEGCKIAKKAIK----PS--EK-NPN-GGFINKEMPMDISNVA------------------- ------------------------KVQ------------E----MGQKVNPIGLRLG--IN-RNWESRWFP------TKA N--LVENIGEDYKIRAFL--KRKLY-----YAGISQILVERTA-K-KLRVTVVAARPGIIIGKKGSDVDNLRKELQDLVN INIKEERK---AGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKA-GAKGIKVSVSGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEARTTYGNIGVKVWIF-MINDIISDSLTRIRNAGMRKLETTKL-LHSKAVEALVGIFQAKGYIESFN VIE----E---D----KKKFINVVLKYD---EKG-------K---SVINNLKRISKPGRRVYKGKDEIKRFKNGYGTIVV STSHGVLANDEAYKAGVGGEILCTIW--MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADIRGPIPMPTKIKRYTVLKS PHINKDSR-EQFEIRIHARMLDIIAATPDTVDSLTKLDLAPEVSVEVRAKREIQGVVVKIAGEKTVSVLVERKVVHPKYR KIVKRFKKYLIHDER--NEVKVGDTVVAVECRPLSKRKSFRLKSVLATG------------------------------- -MARSL-KKGPFVDD-HVMKKVIAAKK---ANDNK----PIKTWSRRSTITPDMIGLTFNVHNGKSFIPVYITE-NHIGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Campylobacter_jejuni_jejuni_81116 Concatenation of 2 sequences MAIKTYKPYTPSRRYITGLSSED-ITA-------------KPSVRSLLVKLPAHAGRNSYGRITSRH-KEAGAKKL---- YRIIDFK-R--RK-FGIEGKVEAIEYDPYRNCRIALIAYK-DGEKRYILQPRGLSVGDIVAAAESG-LD-IKPGNAMKLK NIPVGTIVHNVELKPGKGGQMIRSAGAYAQLMGK--EEKYVILRLASGEMRQVLAECMASIGEVGNEEWANVTIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKK-N--SGRH-PVTP---WGKPTKGAKTR-R-KKASD-K-LIISRR --------------------------------------MEYIVEKIGMSRTI---TNP---------SIAVTLLRVVNAK VCEVE--------------GG---KAL-VAY-------PK---SNK----------CVAGQQK----------------- ---YNLSAEYNRFATLEV-----------ANT-----EA---GDLDETP------LNEAKILKVSFNTKGRGYSGVMKRH NFAG-GPASHGS-RFHRR-HGSIGNR-EWPG-RVQPGMKMAGHYGNTKVTVKN-EVVSYDAENK---------------- ----------ILVVKGA-VPGYNGAMGKIR-MSKVVVLN-DKLEKA-GELDLPSKYA-------EV-NPHNLYLYVKSYL ASLRANTAHTKGRSD--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPT-NERNYFQKVNKKQKRLALERALADKAAKG----------------A-LFTADSL----AIE-S------ --GKTKLIV--KDLLD--E---KTLLAYRNLANCY-V---------------VDVSEVNAYLVSVFNA----VIIEKSAL ESITMRLKEKYNQSI----KPALVKEFDIKNPMLIPVIEKVVISVGAG-ELAKDQKVLQNVADTISLIAGQKAVITKAKK SVAGFKVREGFPVGVMVTLRKENMYAFLDKLISIALPRVKDFRGLSR-DGFDGRGNYNFGLDEQLMFPEVE-----YDKI LRTHGMNISIVTT-----------------------AQNDKQAQKLLELIGVPFMSRIG-K--QPIAIPAGVEVK-L--- -E-G-----NLLKFKKGNLAKELDTKA-N--VNVEIKD-NN--ILF----S-P-KGEDRQSR-AYWGTYRALAYNIVVGL TQGFSKTLEINGVGY--KAALKG-KV--LELS--LGFSHPINYDI-P-E-GIEIVVD--K-N-TIAVKG-SDKQVVGQVA AQIREFR------PPEPY---KGKGVKYSDERIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKVLG-SKRR Y--ATVGDVIVASVKKALPN-G-------KVKKGQVVKAVIVRTKKEIHRDNGSLIRFDENAAVILD-NKRE-PIGTRIF GPVGREVR-YGGFMKIVSLAPEVL------MNLTKAAGS-THKTKRIG-RGQGSGM-GKTATKGGKGQTARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FTSINVEKIITFDSIKSV-HKISIK---------LIG--------A---S----- AKDLVSKIKDENISVTGSK--K---MMK--GRN---RGYA-NRGTEFTFG----------EFALKAT--EAGRINSRQIE AARIALTRFV------KRQGKTWIRVFPDKPLTKKPLETRMGKGK---------GAVEEWVMNIKP-GRIIYEM--AG-- VSEEMAREALTLAMHKLPFKTKF-VKLTLRIKRKKRIRAKI---SGCENFPRISVFKSNRTLYIQAIDD---V--KAVTL AAVD---GRKL---------GVK-ANKEGAKKIAAEFAKT--LKAKK-IEQAVFDRNGYVYH--GVIAALAESLRENGIR L---------------------------------------------------------------M-SKALIKFIRLSPTK ARLIAREVQGMNAELAMASLKFM---------------------------------PNKGAKYIANAISSAVAN----G- -----GFEANEVIVKSCRVDAAAVLKRFRPRARGSASRIRKPTSHILVEVAKKLKIKKGDSVKVITGD------DK-GKT GKVLAVYPKTL--KVV--VEGCKIAKKAIK----PS--EK-NPN-GGFINKEMPMDISNVA-KVQ--E------------ --------------------------------------------MGQKVNPIGLRLG--IN-RNWESRWFP------T-K A-NLVENIGEDYKIRAFL--KRKLY-----YAGISQILVERTA-K-KLRVTVVAARPGIIIGKKGSDVDNLRKELQDLVN INIKEERK---AGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKA-GAKGIKVSVSGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEARTTYGNIGVKVWIF-MINDIISDSLTRIRNAGMRKLETTKL-LHSKVVEALVGIFQAKGYIESFN VIE----E---D----KKKFINVVLKYD---EKG-------K---SVINELKRISKPGRRVYKGKDEIKRFKNGYGTIVV STSHGVLANDEAYKAGVGGEILCTIW--MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADIRGPIPMPTKIKRYTVLKS PHINKDSR-EQFEIRIHARMLDIVAATPDTVDSLTKLDLAPEVSVEVRAKREIQGVVVKIAGEKTASVLVERKVVHPRYR KIVKRFKKYLIHDER--NEVKVGDTVVAVECRPLSKRKSFRLKSVLATG------------------------------- -MARSL-KKGPFVDD-HVMKKVIAAKK---ANDNK----PIKTWSRRSTITPDMIGLTFNVHNGKSFIPVYITE-NHIGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Campylobacter_lari_RM2100 Concatenation of 2 sequences MAIKTYKPYTPSRRYITGVSSED-ITA-------------KASVRSLLVKLPAHAGRNNNGRITSRH-KEAGAKKL---- YRIIDFK-R--RK-FGIEGKVEAIEYDPYRNCRIALISYR-DGEKRYILQPKGLGVGDVVCAAESG-LD-IKPGNAMKLR NIPVGTIVHNIELKPGKGGQMIRSAGAYAQLMGK--EEKYVILRLASGEMRQVLAECMASIGEVGNEEWSNVTIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKK-N--SGRH-PVTP---WGKPTKGAKTR-R-KKASD-K-LIISRR ---------------------------------M----E-YIVEKIGMSRTI---STP---------SIPVTLLKLVQTK VCEVE--------------NGK--ALVAYVK-------GK--ANNK----------CIAGQQK----------------- ---YNLSAEYNRFASLEV------------AN-----TE---AG-DIDL--N-P-LKEASILKVSFNSKGRGYSGVVKRH GFAG-GPASHGS-RFHRR-HGSIGNR-EWPG-RVQPGMKMAGHYGNVKVTVKN-EVVSFDEENG---------------- ----------ILVVKGA-VPGFNGAMGKIR-MSKVTVLN-DKFEKA-SELDLPAKYA-------EV-NPHNLYLYVKSYL ASLRANTAHTKGRSD--------VS-GGGKKPW---------RQKGRGGAR--------AGS---TR-TN----VW---- VGGAVAFGPK-NNRNYFQKVNKKQKRLALERALEDKAAKN----------------A-LFSVDSL----SIE-S------ --GKTKLIV--KDLLD--E---KTLLAFRNLANCY-V---------------VDVNEVNAYLVSVFNA----VIIEKAAL ESIVMRLKEKYTQNI----KPALVKEFDIKNPMLIPFIEKVVISVGAG-ELAKDQKVLQNVADTISLIAGQKAVITKAKK SVAGFKVREGFPVGVMVTLRKDNMYAFLDKLITIALPRVKDFRGLPR-DGFDGRGNYNFGLDEQLMFPEVE-----YDKI LRTHGMNISIVTT-----------------------AKSDKEAQKLLELFGVPFMSRIG-K--QPVAIPSGVEVK-L--- -E-G-----NLLKFKKGNLAKELDTKA-N--VNVEIKE-GQ--ILF----S-P-KGEDRQSR-AYWGTYRALTQNIIIGL TDGFSKTLEINGVGY--KAALKG-KV--LELA--LGFSHPINYAI-P-E-GIEITVD--K-N-NIIVKG-SDKQVVGQVA AQIREFR------PPEPY---KGKGVKYSTERIIRKAGK----------MIQSFTRLAVADNSGAKELMCIKVLG-SKRR Y--ATVGDVIVASVKKALPN-G-------KVKKGQVVKAVIVRTKKEIHRDNGSLIRFDENAAVILD-AKRE-PIGTRIF GPVGREVR-YGGFMKIVSLAPEVL------MNLTKAPGS-THKTKRIG-RGQGSGM-GKTSTKGGKGQTARKGYN-E--- -KRGF-E-GGQQPLQRRLPK-VG--FTSINVEKIITFETINSV-HKLSIK---------LIG--------A---S----- AKDLASKIKDEKITFSGQK--K---MMK--GRN---RGYA-NRGTEFTFG----------DFALKAT--EAGRINSRQIE AARIALTRFV------KRQGKTWIRVFPDKPLTKKPLETRMGKGK---------GAVEEWVMNIKP-GRIIYEM--AG-- VNEEMARQALTLAMHKLPFKTKF-VKLSLRIKRKKRIRAKI---SGTQALPRISVFKSNRTLYIQAIDD---V--KAVTL AAVD---GRKI---------GVK-ANKEGAKKIAAEFAKA--LKAKN-IEEAVFDRNGYLYH--GVIAVLAEALRENGIK L---------------------------------------------------------------M-SRALIKFIRLSPTK ARLIAREVQGMNAELALASLKFM---------------------------------PNKGAKFIANAISSAVAN----G- -----GFEANEVIVSSCRVDAGAVLKRFRPRARGSASRIRKPTSHILVEVSKKLKIKKNDMVKVIAGD------DK-GKT GKVLAVFPKTN--KVI--VEGCKIAKKAVK----PS--DK-NPN-GGFINKEMPMDISNVA-----KA-------GE--- --------------------------------------------MGQKVNPIGLRLG--IN-RNWESRWFP------TKA N--MAENIGEDYKIRTFL--KRKLY-----YAGISQILVERTA-K-KLRVTVVAARPGIIIGKKGSDVDVLRKELQNLVN INIKEERK---AGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKA-GAKGIKVSVSGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEAHTTYGNIGIKVWIF-MINDLISDSLTRIRNAGMRRLETTQL-LHSKVIEALLGIFQAKGYIESFN VIE----E---N----KKKFINVVLKYD---EKG-------K---SVINEVKRVSKPGRRVYKGKDEIKRFKNGYGTIVV STSKGVLANDEAYKAGVGGEVLCTIW--MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADIRGPVPMPTKIKRYTVLKS PHINKDSR-EQFEMRIHARMLDIVAATPDTVDSLTKLDLAPEVNVEVRAKREIQGVVVQIAGDKTATILVERKVVHPKYR KIVKRFKKYLIHDER--NELKVGNTVIAIECRPLSKRKSFRLKTIVSAG------------------------------- -MARSL-KKGPFVDD-HVMKKVIAAKK---VNDGK----PIKTWSRRSTIIPDMIGLTFNVHNGKSFIPVYITE-NHIGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Helicobacter_acinonychis_Sheeba Concatenation of 2 sequences MAIKTYKPYTPSRRFMSVLDSKD-ITAK------------SS-VKGLLTKLKATAGRNNNGRITSRH-KERGAKKL---- YRIIDFK-R--NK-YNIEGKVVAIEYDPYRNARIALVVYP-DGDKRYILQPSGLKVGDSVIAAE-GGLD-IKVGFAMKLK NIPIGTVVHNIEMHPGAGGQLARSAGMSAQIMGR--ENKYTIIRMPSSEMRYILSECMASIGVVGNEDFINVSIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKT----GTSGHPVSP---WGTPAKGYKTR-KKKA-SD-K-LIISRK ---------------------------------ME-----FLVQKIGMSRTI---DAN---------STPVTLLKVLQAK VCQLE--------------NG---KAL-VAY-------AM---HNK----------AIEGQQK----------------- ---YQLSKEFNHFATLKA--------SQQKEL----------GDLDLSA------LETLKRVKASFKTKGRGFAGVMKRW NFQG-GPAAHGS-RFHRR-PGSIGNR-EWPG-RVQKGRKMAGHYGNELVTCQN-EVLSFDKESM---------------- ----------VLVLKGS-VAGFSGAYGRIR-MSKAIVLD-SHLKEK-GSMELPKRYE----GI----NSHNLYLYVKHYL SSVRANTAKSKNRAE--------VS-GGGRKPW---------AQKGGGRAR--------AGS---IT-SP----VF---- VGGGVSHGATNN-RNYNLKINKKQKRLALEYALEEKAQAN----------------K-LFVVEKI----AIK-GVVEYNK RKHLAKLFV--CMNMD--E---YTELAFSNLKKCL-V---------------IDVSELNAYLLAAFSS----VVMEEVAF QHVVFGLKQFYQNEV----KVKLAQELDIKNPMLLPKLEKIVISVGAG-AHAKDMKIMQNIAQTISLIAGQKAVITKAKK SVAGFKIREGMAVGAKVTLRNKRMYNFLEKLIVISLPRVKDFRGISR-NGFDGRGNYTFGINEQLIFPEVV-----YDDI MVSHGMNITMVTS-----------------------TDNDKEAFKLLELLGLPFMSRIG-K--RIIEIPSSVQAS-V--- -E-G--S-KLLFKNNKEKHELET--HN-R--VKITLEN-NQ--LSF----Q-P-IGEDVQSR-AYWGTYGALANNIVIGL STGFSKTLEVNGVGY--KVALGN-KT--LDLS--LGFSHPVKYPI-P-A-GIEMVVE--K-N-TITIKG-SDKQKVGQVA AEIRSFR------PPEPY---KGKGVKYSDEVIIRKAGK----------MIQSFTRLNVADNSGAKEIMCIKVLG-SHKR Y--ASVGSVIVASVKKAIPN-G-------KVKRGQVVKAVVVRTKKEIQRKNGSLVRFDDNAAVILD-AKKD-PVGTRIF GPVSREVR-YANFMKIISLAPEVVMG-L--ENLKSAKGS-VKKIKRVG-RGQGSGM-GKTATRGGKGQTARTGYK-A--- -KRGF-E-GGQQPLQRRLPK-IG--FRTINVDKNITFSSLRSL-HHFPVK---------LIG------------K----- DAKILASKIKDKRIKTSGQK-K---QMK--GRN---RGKA-HRGNSIAFG----------DIAIKAI--EHGRIDSRQIE SARVAMTRHV------KRAGKVWIRVFPDKPLTAKPLETRMGKGK---------GSVEKWVMNIKP-GRIVYEM--LG-- IEEGLAREALALAQSKLPFKTKI-VKKALRDRRKLRIKSKL---LGDALRPRVSVFRSNRYFYAQAIDD---V--KQSTI THID---GRKM---------GFK-NTQEDAKKLGVLFAEE--LKKAG-IERVVYDRNGYLYH--GVVAAFAESLRENGIA L---------------------------------------------------------------M-SKALLRFVRLSPTK ARLIARQIQGMNVELAIASLEFT---------------------------------PNKAGRVLSKVVASAVAN----G- -----SLDAKSALIVSCRVDAGPVIRRSIPRAKGRATAIRKPTSHVFVEVAEKSEIKKNDMVKVIAGD------DK-GKV AKVLAVLPKTS--QVI--VEGCKVVKKAIK----PT--DD-NPK-GGFIHKEKPMHISNVK------------------- ----------------------KA--------------------MGQKVNPVGLRLG--IN-RNWTSRWFP------SAR T--APSNIDEDNKIRKFL--KKELY-----YAGVSQIVIERAA-K-KLRVTVVAARPGLIIGKKGVDIEKVKEGLKTLVS INIKEVKR---PQADAQLAAENVATQLEKRVAFRRAMKKVMQAALKS-GAKGVKVRVSGRLAGAEIARTEWYMEGRVPL- -HTLRAKIDYGFAEAMTVYGIIGVKVWIF-MVNDIIADSLTRLRNASMRRLEFTQL-YYAKIVVSILEIFKEKGFIKDFN IKD----K---D----KKQSVYVQLAYD---EKG-------Y---SKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVV STSKGVITNEEAYRQNVGGEVLCSIW--MEKIRLKLKAYDHRVLDRSVVAIVEAVKRSGSEIRGPIPLPTKNKRYTVLRS PHVNKDSR-EQFEIRVYSRLIDIISATPETVDSLMKLDLAPEVDVEVTSKRVVQGKVISKFAEKSAVILVERKVVHKKYR KIVKKFKKYTIHDQD--NQVKVGDFVSAIECKPLSKTKSFTLKEILVVG------------------------------- -MSRSI-KKGPFIDD-HLMKKTLKAKE---SKDNR----PIKTWSRRSTILPEMIGFTYNVHNGRVFIPVYITE-NHVGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Helicobacter_hepaticus_ATCC_51449 Concatenation of 2 sequences MAVKTYKPYTPSRRFMSNLSSSD-ITGK------------AS-VKSLLIKLPVSAGRNNNGRITSRH-KEGGAKKF---- YRIIDFK-R--NK-FNIQGKVAAIEYDPYRNCRIALIHYV-DGEKRYIIQPSGLKVGDVVFSAS-SGLD-IKTGFAMKLK SMPIGTIVHNIEMHPGAGGALARSAGTSAQIMGR--EGKYIILRMPSGEMRYILEECMATIGVVGNEDFANISIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKT----GSSGHPVSP---WGTPAKGFKTR-KKKA-SD-K-LIISRK --------------------------------MSR-----TIGTK----------------------SEAVTLLRVLGAK VCEIY-----------D--NG---KAL-VAY-------SQ---VNK----------AIAGQQK----------------- ---YSLSKEFNRFATLKV---------SNKEV----------GELDVAS------LSEAKRVQVSFKTKGRGFSGAMKRW NFQG-GPGAHGS-RFHRR-LGSIGNR-EWPG-RVQPGKKMAGHYGNELVSAKN-DIMSFDKQSA---------------- ----------ILVLKGS-VAGFNGAFGRIQ-MSKAILLD-KKLQQS-NELALPERYA-------QI-KEHNLYLYVKSYL SSLRANSASAKKRGE--------VS-GGGKKPW---------KQKGGGRAR--------AGS---IT-SP----VF---- VGGGVSHGPS-NDKNYTLKINKKQKRLALECALFQKAQEG----------------K-LFVVDSL----AMP-S------ --GKTKLFV---AQMD--E---PTFLAFRNLQQCY-L---------------ADANELNAYLVAAFRS----VVIEKAVF DEIIFALREKYKNEI----ISQLKSELNMSNPMLLPKLEKIVISVGAG-DYAKDSKIMQNIADTISLIAGQKAVITLAKK SVAGFKMREGMPMGVKVTLRGKMMYNFLEKLIVIALPRVKDFRGLKR-NGFDGRGNYSFGLNEQLMFPEVV-----YDDI MVTHGMNITIVTS-----------------------THSDKEAFKLLELLGMPFMSRVG-K--KPINIPKGVEVS-V--- -Q-G--S-KILFKGAKEQKELET--YG-R--VQIHLQD-GT--LSF----A-C--VDSAQSR-AYWGTYRALANNIIVGL SQGFTKVLEINGVGY--KANISG-KN--LEMA--LGFSHPVIYPI-P-A-GVEMSVD--K-NT-ITIKG-ADKQQIGQIA AEIRKFR------PPEPY---KGKGIKYSDEMIVRKAGK----------MIQSFTRLSVADNSGAKEIMCIKILG-SHRR Y--ARVGDVIVASVKKAIPN-G-------KVKKGQVVKAVVVRTKKEIHRENGSLVRFDDNAAVILD-AKKE-PIGTRIF GPVSREVR-YANFMKIVSLAPEVL-M-L--EKIKPANGS-VRKIKRIG-RGQGSGM-GKTSTRGGKGQTARSGYK-A--- -KRGF-E-GGQQPLQRRLPK-IG--FSSINVDKTINMEVLRTH-FSIPVK---------LIG----------K-K----- AKALMSKIKDECIKTSGSKE-K---QMK--GRN---RGKS-FRGANLAFG----------DIGIKAI--EHGRIDSRQIE SARIAMTRHI------KRAGKVWIRVFPDKPLTAKPLETRMGKGK---------GGVEKWVMNIKP-GRLIYEM--AG-- IDEALAREALALAQSKLPFKTKI-IKQLLKVKRKLRTRGKI---FGRADKPRVSVFKSNKYFYAQAIND---E--LGVTL ASVD---GKKL---------GLG-NNKENAKQIANEFATS--LKKAK-ITEVVFDRNGYLYH--GVVAAFADTLRENGIK L---------------------------------------------------------------M-SRALLKYIRLSPTK ARLVARQVQGMNAEIAIASLEFT---------------------------------PNKAARVISKVIASAVAN----G- -----GYDAQDVIILSCRVDAGPVLRRFMPRAKGRATPIRKPMAHILVEVGTKFKIKKGDMVQVIAGD------DK-GKK AKVLQVLPKQA--QVI--VEGCKVVKKAIK----VS--EK-NPK-GGFVSKEMPMSISNVK-KAEGDN------------ --------------------------------------------MGQKVNPIGLRLG--IN-RNWSSRWFS------VSQ T--TPSNILEDHKIRKFL--KREMY-----YAGVSEFIIERAA-N-KIRVTVVASRPGLIIGKKGVDIDKHKEALKKIVF INIKEAKR---PQANAQLAAENIATQLEKRVAFRRAMKKVMQAAMKA-GAKGIKVKVSGRLAGAEMARTEWYMEGRVPL- -HTLRAKIDYGFAEAMTTYGIIGVKVWIF-MVNDIIADSLTRIRNASMRRLEVTTL-YYAKIVVSIVEVFKTKGFIKDYK VND----K---D----GKRSIMVQLAYD---EQG-------K---SAINEIKRISKPGRRVYKARSELKRFKNGYGTIVV STSKGVVANDEAYKANVGGEALCSIW--MERIRLRLKAYDHRVLDRSVASIVEAVKRTGSEIRGPVPLPTKKKRYTVLRS PHINKDSR-EQFEIRVHHRIIDIMSATPDTVDSLMKLDLAPEVDVEVMSTRVIQGKVISQAGNKSIVILVERKVVHSKYR KIVKRFKKYTIHDEN--QSAKIGDVVSAIECKPISKTKAFRFKEIITAG------------------------------- -MARSI-KKGPFVDD-YLVKKVEKAKA---SKDNK----PIKTWSRRSTILPDMIGLTFNVHNGRAFVPVYITE-NHVGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Helicobacter_pylori_26695 Concatenation of 2 sequences MAIKTYKPYTPSRRFMSVLDSKD-ITAK------------SS-VKGLLTKLKATAGRNNNGRITSRH-KERGAKKL---- YRIIDFK-R--NK-YNIEGKVAAIEYDPYRNARIALVVYP-DGDKRYILQPSGLKVGDSVIAAE-GGLD-IKVGFAMKLK NIPIGTVVHNIEMHPGAGGQLARSAGMSAQIMGR--ENKYTIIRMPSSEMRYILSECMASVGVVGNEDFINVSIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKT----GTSGHPVSP---WGTPAKGYKTR-KKKA-SD-K-LIISRK ---------------------------------ME-----FLVQKIGMSRTI---DAN---------STPVTLLKVLQAK VCQLE--------------NG---KAL-VAY-------AM---HNK----------AIEGQQK----------------- ---YQLSKEFNHFATLKA--------SQQKEL----------GDLDLSA------LETLKRVKASFKTKGRGFAGVMKRW NFQG-GPAAHGS-RFHRR-PGSIGNR-EWPG-RVQKGRKMAGHYGNELVTCQN-EVLSFDKESM---------------- ----------VLVLKGS-VAGFSGAYGRIR-MSKAIVLD-SHLKEK-GSVELPKRYE----SI----NSHNLYLYVKHYL SSARANTAKSKNRAE--------VS-GGGRKPW---------AQKGGGRAR--------AGS---IT-SP----VF---- VGGGVSHGATNN-RNYNLKINKKQKRLALEYALEEKAQAN----------------K-LFVVEKI----AIK-GVVEDNK RKHLTKLFV--CMNMD--E---YTELAFSNLKKCL-I---------------VDVSELNAYLLAAFSS----VVMEEAAF QHVVFGLKQFYQSEV----RTKLAQELDIKNPMLLPKLEKIVISVGAG-AHAKDMKIMQNIAQTISLIAGQKAVITKAKK SVAGFKIREGMAVGAKVTLRNKRMYNFLEKLIVISLPRVKDFRGISR-NGFDGCGNYTFGINEQLIFPEVV-----YDDI MVSHGMNITMVTS-----------------------TDNDKEAFKLLELLGLPFMSRIG-K--RIIEIPSSVQAS-V--- -E-G--S-KLLFKNSKEKHELET--HN-R--VKITLEN-NQ--LSF----Q-P-VGEDAQSR-AYWGTYGALANNIVIGL STGFSKTLEVNGVGY--KVALGN-KT--LDLS--LGFSHPVKYPI-P-A-GIEMVVE--K-N-TITIKG-SDKQKVGQVA AEIRSFR------PPEPY---KGKGVKYSDEVIIRKAGK----------MIQSFTRLNVADNSGAKEIMCIKVLG-SHKR Y--ASVGSVIVASVKKAIPN-G-------KVKRGQVVKAVVVRTKKEIQRKNGSLVRFDDNAAVILD-AKKD-PVGTRIF GPVSREVR-YANFMKIISLAPEVVMG-L--ENLKPAKGS-VKKIKRVG-RGQGSGM-GKTATRGGKGQTARTGYK-A--- -KRGF-E-GGQQPLQRRLPK-IG--FRTINVEKNITFSSLRAL-HHFPVK---------LIG------------K----- DAKNLASKIKDERIKTSGQK-K---QMK--GRN---RGKA-HRGNSIAFG----------DIAIKAI--EHGRIDSRQIE SARVAMTRHI------KRAGKVWIRVFPDKPLTAKPLETRMGKGK---------GSVEKWVMNIKP-GRIVYEM--LG-- IEEGLAREALALAQSKLPFKTKI-VKKALRDRRKLRIKSKL---LGDALRPRVSVFRSNRYFYAQAIDD---V--KQSTI THID---GRKM---------GFK-NTQEDAKKLGALFAEE--LKKAG-IERAVYDRNGYLYH--GVVAAFAESLRENGIA L---------------------------------------------------------------M-SKALLRFVRLSPTK ARLIARQIQGMNAELAIASLEFT---------------------------------PNKAARVLSKVVASAVAN----G- -----SLDAKSALIVSCRVDAGPVLRRSIPRAKGRATAIRKPTSHVFVEVAEKSEIKKNDIVKVIAGD------DK-GKV AKVLAVLPKTS--QVV--VEGCKVVKKAIK----PT--DD-NPK-GGFIHKEKPMHISNVK------------------- ----------------------KA--------------------MGQKVNPVGLRLG--IN-RNWTSRWFP------SAR T--APSNIDEDNKIRKFL--KKELY-----YAGVSEIVIERAA-K-KLRVTVVAARPGLIIGKKGVDIEKVKDGLKTLVS INIKEVKH---PQADAQLAAENVATQLEKRVAFRRAMKKVMQAALKS-GAKGIKVCVSGRLAGAEIARTEWYMEGRVPL- -HTLRAKIDYGFAEAMTVYGIIGVKVWIF-MVNDIIADSLTRLRNASMRRLEFTQL-YYAKIVVSILEIFKEKGFIKDFN VKD----K---D----KKQSVYVQLAYD---EKG-------H---SKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVV STSKGVITNEEAYRQNVGGEVLCSIW--MEKIRLKLKAYDHRVLDRSVVAIVEAVKRSGSEIRGPIPLPTKNKRYTVLRS PHVNKDSR-EQFEIRVYSRLIDIISATPETVDSLMKLDLAPEVDVEVTSKRLVQGKVISKFAEKSAVILVERKVVHEKYR KIVKKFKKYTIHDEN--NQVKVGDFVSAIECRPLSKTKSFTLKEILVVG------------------------------- -MSRSI-KKGPFIDD-HLMKKTLKAKE---GKDNR----PIKTWSRRSTILPEMIGFTYNVHNGRVFIPVYITE-NHVGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Helicobacter_pylori_G27 Concatenation of 2 sequences MAIKTYKPYTPSRRFMSVLDSKD-ITAK------------SS-VKGLLTKLKATAGRNNNGRITSRH-KERGAKKL---- YRIIDFK-R--NK-YNIEGKVAAIEYDPYRNARIALVVYP-DGDKRYILQPSGLKVGDSVIAAE-GGLD-IKVGFAMKLK NIPIGTVVHNIEMHPGAGGQLARSAGMSAQIMGR--ENKYTILRMPSSEMRYILSECMASVGVVGNEDFINVSIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKT----GTSGHPVSP---WGTPAKGYKTR-KKKA-SD-K-LIISRK --------------------------------ME------FLVQKIGMSRTI---DAN---------STPVTLLKVLQAK VCQLE--------------NG---KAL-VAY-------AM---HNK----------AIEGQQK----------------- ---YQLSKEFNHFATLKA--------SQQKEL----------GDLDLSA------LETLKRVKASFKTKGRGFAGVMKRW NFQG-GPAAHGS-RFHRR-PGSIGNR-EWPG-RVQKGRKMAGHYGNELVTCQN-EVLSFDKESM---------------- ----------VLVLKGS-VAGFSGAYGRIR-MSKAIVLD-SHLKEK-GSMELPKRYE----GI----NSHNLYLYVKHYL SSARANTAKSKNRAE--------VS-GGGRKPW---------AQKGGGRAR--------AGS---IT-SP----VF---- VGGGVSHGATNK-RNYNLKINKKQKRLALEYALEEKAQAN----------------K-LFVVEKI----AIK-GVVEDNK RKHLTKLFV--CMNMD--E---YTELAFSNLKKCL-I---------------IDVNELNAYLLAAFSS----VVMEEAAF QHIVFGLKQFYQDEV----RAKLAQELDIKNPMLLPKLEKIVISVGAG-AHAKDMKIMQNIAQTISLIAGQKAVITKAKK SVAGFKIREGMAVGAKVTLRNKRMYNFLEKLIVISLPRVKDFRGISR-NGFDGRGNYTFGINEQLIFPEVV-----YDDI MVSHGMNITMVTS-----------------------TDNDKEAFKLLELLGLPFMSRIG-K--RIIEIPSSVQAS-V--- -E-G--S-KLLFKNSKEKHELET--HN-R--VKITLEN-NQ--LSF----Q-P-VGEDAQSR-AYWGTYGALANNIVTGL STGFSKTLEVNGVGY--KVALGN-KT--LDLS--LGFSHPVKYPI-P-A-GIEMVVE--K-N-TITIKG-SDKQKVGQVA AEIRSFR------PPEPY---KGKGVKYSDEVIIRKAGK----------MIQSFTRLNVADNSGAKEIMCIKVLG-SHKR Y--ASVGSVIVASVKKAIPN-G-------KVKRGQVVKAVVVRTKKEIQRKNGSLVRFDDNAAVILD-AKKD-PVGTRIF GPVSREVR-YANFMKIISLAPEVVMG-L--ENLKPAKGS-VKKIKRVG-RGQGSGM-GKTATRGGKGQTARTGYK-A--- -KRGF-E-GGQQPLQRRLPK-IG--FRTINVEKNITFSSLRAL-HHFPVK---------LIG------------K----- DAKNLASKIKDERIKTSGQK-K---QMK--GRN---RGKA-HRGNSIAFG----------DIAIKAI--EHGRIDSRQIE SARVAMTRHI------KRAGKVWIRVFPDKPLTAKPLETRMGKGK---------GSVEKWVMNIKP-GRIVYEM--LG-- IEEGLAREALALAQSKLPFKTKI-VKKALRDRRKLRIKSKL---LGDALRPRVSVFRSNRYFYAQAIDD---V--KQSTI THID---GRKM---------GFK-NTQEDAKKLGALFAEE--LKKAG-IERAVYDRNGYLYH--GVVAAFAESLRENGIA L---------------------------------------------------------------M-SKALLRFVRLSPTK ARLIARQIQGMNAELAIASLEFT---------------------------------PNKAARVLSKVVASAVAN----G- -----SLDAKSTLIVSCRVDAGPVLRRSIPRAKGRATAIRKPTSHVFVEVAE--------MVKVIAGD------DK-GKV AKVLAVLPKTS--QVV--VEGCKVVKKAIK----PT--DD-NPK-GGFIHKEKPMHISNVK------------------- ----------------------KA--------------------MGQKVNPVGLRLG--IN-RNWTSRWFP------SAR T--APSNIDEDNKIRKFL--KKELY-----YAGVSEIVIERAA-K-KLRVTVVAARPGLIIGKKGVDIEKVKEGLKTLVS INIKEVKR---PQADAQLAAENVATQLEKRVAFRRAMKKVMQAALKS-GAKGIKVRVSGRLAGAEIARTEWYMEGRVPL- -HTLRAKIDYGFAEAMTVYGIIGVKVWIF-MVNDIIADSLTRLRNASMRRLEFTQL-YYAKIVVSILEIFKEKGFIKDFN VKD----K---D----KKQSVYVQLAYD---EKG-------H---SKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVV STSKGVITNEEAYRQNVGGEVLCSIW--MEKIRLKLKAYDHRVLDRSVVAIVEAVKRSGSEIRGPIPLPTKNKRYTVLRS PHVNKDSR-EQFEIRVYSRLIDIISATPETVDSLMKLDLAPEVDVEVTSKRLVQGKVISKFAEKSAVILVERKVVHEKYR KIVKKFKKYTIHDEN--NQVKVGDFVSAIECRPLSKTKSFTLKEILVVG------------------------------- -MSRSI-KKGPFIDD-HLMKKTLKAKE---GKDNR----PIKTWSRRSTILPEMIGFTYNVHNGRVFVPVYITE-NHVGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Helicobacter_pylori_Shi470 Concatenation of 2 sequences MAIKTYKPYTPSRRFMSVLDSKD-ITAK------------SS-VKGLLTKLKATAGRNNNGRITSRH-KERGAKKL---- YRIIDFK-R--NK-YNIEGKVAAIEYDPYRNARIALVVYP-DGDKRYILQPSGLKVGDSVIAAE-GGLD-IKVGFAMKLK NIPIGTVVHNIEMHPGAGGQLARSAGMSAQIMGR--ENKYTILRMPSSEMRYILSECMASVGVVGNEDFINVSIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKT----GTSGHPVSP---WGTPAKGYKTR-KKKA-SD-K-LIISRK --------------------------------------MEFLVQKIGMSRTI---DAN---------STPVTLLKVLQAK VCQLE--------------NGK--ALVAYAM------------HNK----------AIEGQQK----------------- ---YQLSKEFNHFATLKA--------SQQKEL----------GDLDLSA------LETLKRVKASFKTKGRGFAGVMKRW NFQG-GPAAHGS-RFHRR-PGSIGNR-EWPG-RVQKGRKMAGHYGNELVTCQN-EVLSFDKESM---------------- ----------VLALKGS-VAGFSGAYGRIR-MSKAIVLD-SHLKEK-GSVELPKRYE----GI----NSHNLYLYVKHYL SSARANTAKSKNRAE--------VS-GGGRKPW---------AQKGGGRAR--------AGS---IT-SP----VF---- VGGGVSHGAT-NNRNYNLKINKKQKRLALEYALEEKAQAN----------------K-LFVVEKI----AIK-GVVEDNK RKHLTKLFV--CMNMD--E---YTELAFSNLKKCL-I---------------IDVSELNAYLLAAFSS----VVMEEAAF QHVVFGLKQFYQNEV----RAKLAQELDIKNPMLLPKLEKIVISVGAG-AHAKDMKIMQNIAQTISLIAGQKAVITKAKK SVAGFKIREGMAVGAKVTLRNKRMYNFLEKLIVISLPRVKDFRGISR-NGFDGRGNYTFGINEQLIFPEVV-----YDDI MVSHGMNITMVTS-----------------------TDSDKEAFKLLELLGLPFMSRIG-K--RIIEIPSSVQAS-V--- -E-G--S-KLLFKNSKEKHELET--HN-R--VKITLEN-NQ--LSF----Q-P-VGEDAQSR-AYWGTYGALANNIVIGL STGFSKTLEVNGVGY--KVALGN-KT--LDLS--LGFSHPVKYPI-P-A-GIEMVVE--K-N-TITIKG-SDKQKVGQVA AEIRSFR------PPEPY---KGKGVKYSDEVIIRKAGK----------MIQSFTRLNVADNSGAKEIMCIKVLG-SHKR Y--ASVGSVIVASVKKAIPN-G-------KVKRGQVVKAVVVRTKKEIQRKNGSLVRFDDNAAVILD-AKKD-PVGTRIF GPVSREVR-YANFMKIISLAPEVVMG-L--ENLKPAKGS-VKKIKRVG-RGQGSGM-GKTATRGGKGQTARTGYK-A--- -KRGF-E-GGQQPLQRRLPK-IG--FRTINVEKNITFSSLRAL-HHFPVK---------LIG------------K----- DAKNLASKIKDERIKTSGQK-K---QMK--GRN---RGKA-HRGNSIAFG----------DIAIKAI--EHGRIDSRQIE SARVAMTRHI------KRAGKVWIRVFPDKPLTAKPLETRMGKGK---------GSVEKWVMNIKP-GRIVYEM--LG-- IEEGLAREALALAQSKLPFKTKI-VKKALRDRRKLRIKSKL---AGDALRPRVSVFRSNRYFYAQAIDD---V--KQSTI THID---GRKM---------GFK-NTQEDAKKLGTLFAEE--LKKAG-IERAVYDRNGYLYH--GVVAAFAESLRENGIA L---------------------------------------------------------------M-SKALLKFVRLSPTK ARLIARQIQGMNAELAIASLEFT---------------------------------PNKAARVLSKVVASAVAN----G- -----SLDAKSALIVSCRVDAGPVLRRSIPRAKGRATAIRKPTSHVFVEVAEKSEIKKNDMVKVIAGD------DK-GKV AKVLAVLPKTS--QVV--VEGCKVVKKAIK----PT--DD-NPK-GGFIHKEKPMHISNV---------------KK--A --------------------------------------------MGQKVNPVGLRLG--IN-RNWTSRWFP------SAR T--APSNIDEDNKIRKFL--KKELY-----YAGVSEIVIERAA-K-KLRVTVVAARPGLIIGKKGVDIEKVKEGLKTLVS INIKEVKR---PQADAQLAAENVATQLEKRVAFRRAMKKVMQAALKS-GAKGIKVRVSGRLAGAEIARTEWYMEGRVPL- -HTLRAKIDYGFAEAMTVYGIIGVKVWIF-MVNDIIADSLTRLRNASMRRLEFTQL-YYAKIVVSILEIFKEKGFIKDFN VKD----K---D----KKQSVYVQLAYD---EKG-------H---SKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVV STSKGVITNEEAYRQNVGGEVLCSIW--MEKIRLKLKAYDHRVLDRSVVAIVEAVKRSGSEIRGPIPLPTKNKRYTVLRS PHVNKDSR-EQFEIRVYSRLIDIISATPETVDSLMKLDLAPEVDVEVTSKRLVQGKVISKFAEKSAVILVERKVVHEKYR KIVKKFKKYTIHDEN--NQVKVGDFVSAIECRPLSKTKSFTLKEILVVG------------------------------- -MSRSI-KKGPFIDD-HLMKKTLKAKE---GKDNR----PIKTWSRRSTILPEMIGFTYNVHNGRVFVPVYITE-NHVGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Nautilia_profundicola_Am-H Concatenation of 2 sequences MAVKSYKPYTPSRRFMTTLDNSD-ITS-------------KPTVKKLLIKLPQKAGRNNLGRITSRH-REAGAKKL---- YRIIDFK-R--NK-FGVPGKVATVEYDPYRNCRICLISYV-DGDKRYIIQPEGLKVGDTVMAAEAG-LD-IKPGNAMKLK NIPVGTVVHNVEMKPGKGGQIARSAGNSCQIMGR--EGKYVILRLPSGEMRYILGECMATIGTVGNAEYQNITIGKAGRS -RHL-----GIR-P-QTRGIAMNPVDHPHGGGEGRS----KGNH-PVTP---WGMPTKGYKTR-K-KKQSD-K-YIISRR --------------------------------------MEFIVEKIGMSRTVGIP------------SIPVTLLKVVPAK VCEIK--------------DD---KALVAYA------NGK---LNK----------AIEGMQK----------------- ---YGLDKEFNRFVELKV-----------ANT-----EP---GDLSIEP------LKEAKKVKLTFKSKGRGFQGVVKRH GFAG-GPGGHGS-RFHRA-PGSIGNC-EWPG-RVMPGRKMPGQYGNKNVTV-NAEVLEYDENMG---------------- ----------VLVIKGS-VPGANGSLGRVR--MSIEVIK-----------QLPEDFQ----NI----NPHNLYLYVKAYL ANQRAGTAHTKTRGE--------VS-GGGKKPF---------RQKGLGRAR--------QGS---IR-AP----QF---- VGGGVAHGPR-NERDWSQKLNKKQKRVALKYALNEKAENG----------------K-LFVVDSI----KIE-S------ --GKTKLIV--VDEMD--E---KTFLAFRNIPNVY-I---------------ITPEELNAYYASVFHS----IIFDKAAY EKV-FEVQKKYKDEV----RAKLAEEFDIKNPMLIPNIEKIVVSAGVG-EGSKDKKFLQSVADTLTIITGQKAVITPAKK SVAGFKVREGMPVGVKVTLRGEMMWNFLQKLISIALPRVRDFKGVKR-DGFDGRGNFNFGLTEQLVFTEVD-----YDSI IRVHGMNINISTT-----------------------TEDDKQAERMLELIGFPFMSRIG-K--QPVKLASGLEAK-L--- -E-G--N-KLIIKKGQDEKVIDT--KG-V--VKVNING-DE--LTF----E-P--VEEKFAK-AMWGTVRALANNAVIGL TQGFEKKLEINGVGY--RAQVKG-NI--LELQ--LGYSHPINFEI-P-K-GITITVE--K-NI-ITVKG-SDKQQVGQVA SEIRSFR------KPEPY---KGKGVKYVDEHIIRKAGK----------MIQPFTRLKVADNSGAKEIMCIKVLG-SKRR Y--ASVGDIIVASVKKALPN-G-------KIKKGQVVKAVIVRTKKEVQRENGSLIRFDDNAAVIID-AKKE-PIGTRIF GPIAREVR-YEGFQKITSLAPEVLMA-L--NNLKPACGS-THKTKRVG-RGAGSGY-GKTSTRGQKGQKSRTGYS-K--- -KRGF-E-GGQQPLQRRLPK-VG--FKSINVDKFITMEALANI-VKIKVK---------LIG----------T-K----- AKELKDKIKDANITTSGK---K---QQK--GRN---RGKA-YRGSTLAFG----------TYGLKAV--ELGRINSRQIE AGRVALSRTM------KRTGKIWIRVFPDKPLTAKPVGVRMGKGK---------GSVEEWVMNIKP-GRIIFEI--TG-- VNNETAVRALTLAAAKLPFKTKI-VRDLRRLKRKRRVRGRI---SGTADMPRVTIYKSNKYIVVQAIDD---V--AGNTL AFLNTA-HLEN---------KLP-SNINGAKEAAKIFAEK--LKAAN-IDSVRFDRNGYKYH--GVVAAFADTLRENGIK L---------------------------------------------------------------M-SKAVLKFIRLSPTK ARLIAKEIQGMNAEEALAKLEFM---------------------------------PNKAARVIAKVVASAVAN----G- -----GYDANEVVITSCRIDRGPYLKRFRPRARGMASRIQKPTAHIFVEVEKKFKIKKGDTVKVIAGD------DR-GKT GEVLKVLVKDE--KVL--VKGVNVVKKAVK----PT--EQ-NPK-GGFEYIEKPIHISNVK------------------- ------------------------KVE--------G--------MGQKTNPIGLRLG--IN-KNWRSRWFI------NYN T--MPENVLGDYELRKFL--KKKLY-----YAGISDIIIERTA-K-KIRITIFAAKPGIIIGKGGSEIEALKAELQKRLI LNIKEERK---PQLSAQLAAENVATQIERRVAFRRAMKKVIQSALKS-GAKGIKVQVAGRLNGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEALTTYGIIGVKVWIF-MMNDIIADGLTRIRNAAMRGLEVTQL-NHSKLMEAVLKVFEDKGYIESFK VVE----D---G----NKKFINVTLKYD---ENG-------N---SVINEVKKVSKPGRRVYKGYEDIKRFKNGYGTLVV STNKGVLPNDEAYKLKVGGEVICSIW--MEKIRIKLQAYDHRVLDKAVSIITDAIKRTGAEVKGPIPLPTKIRRYTVLRS PHINKDSR-EQFEIRIHRRIVDVVNASPETVDQLMKLELAPEVDVEVRAKRIITGKVIKKTGDKTINVLVERKVLHPKYH KIVKKFKKYLVHDEN--NEANVGDVVSAIEHRPISKRKSFVLKDILERG------------------------------- -MARSL-KKGPFVDD-HLMKKVLKAKE---EKNPK----PIKTWSRRSTITPDMIGLTINVHNGRDFVPVYVTE-RHVGF KLGEFAPTRTFRGHK------GSVQKK----IGK-------- >EPSI_Nitratiruptor_sp_SB155-2 Concatenation of 2 sequences MAVKKYKPYTPSRRFMSVVDSSD-ITA-------------KPSVRKLLVKLPARAGRNNQGRITSRH-REAGAKKL---- YRIIDFK-R--NK-YGVPGRVATIEYDPYRNCRIALVVYR-DGDKRYIIQPSGLKVGDTVEAAEAG-LD-VLPGNAMKLK NIPVGTLVHNIEMKPGKGGQLARSAGAYAQIMGR--EDKYVILRLPSGEMRKILGECMATIGVVGNEEYANIVIGKAGRN -RHR-----GIR-P-QTRGSAMNPVDHPHGGGEGKT-G--PSGH-PVTP---WGMPTKGYKTR-R-KKPSD-K-LIISRR --------------------------------------MEYIVEKIGMSRTISVP------------SVPVTLLKVKEAK VCELL--------------EG---GKAIVAY-------SQ---RNK----------AIEGQQK----------------- ---YGLSPEFNRFIKLKV-----------TNT-----EA---GDLDVTP------LSEAKRIKTSFNSKGRGFSGVVKRW NFGG-GPDSHGS-RFHRA-PGSVGMC-EWPG-RIMPGQKMPGQYGNKKVTVQN-EVVSFDPENM---------------- ----------ILVVKGS-IPGPNGALGKVR-MSKAVVLN-ENFEKA-SEVALPEHFQ----GI----NPHNLYLYAKAYA ANLRANNAHTKSRGE--------VS-GGGRKPW---------QQKGRGGAR--------AGS---IR-SP----LF---- VGGGVAFGPK-NTKNYTQKVNKKQKRKALEFALNEKGEQG----------------A-LFIVDSI----AVE-S------ --GKTKLVV--KENID--E---KTFLAFRNLPNAY-L---------------IEPNELNAYLAAAFRA----VVIERPVW EKIVLELKKKYQEEV----APALKEELGLANPMLTPKLEKIVISVGAG-EASRDSKLMQNIQDTISLIAGQHAVVTKARK SEAGFKIREGMPVGVRVTLRGDRMWNFLQKLIYIALPRVKDFRGLPR-SGFDGRGNYNFGLDEQLMFPEVD-----YDNI IKTHGMNITIVTS-----------------------TDNDKEAFTMLEKLGFPFMSRIG-K--QPVAIPSGVDVK-I--- -ENG------KIIAKKGNLTQEV-EFGNR--VNVSIED-NK--IVF----S-P--VGEKQSK-AFWGTYRALTNNAIEGL TKGFEKKLEINGVGY--RAAVKG-KE--LELQ--LGFSHPILYPI-P-E-GIQISVE--K-N-IITIKG-HDKQKVGQVA AEIRSFR------PPEPY---KGKGVKYVDEVIIRKAGK----------MIQSFTRLNVADNSGAKEIMAIKVLG-SKRR Y--ASVGDVIVASVKKALPN-G-------KVKKGQVVKAVVVRTKKEIQRENGSLIRFDDNAAVILD-NKNE-PIGTRIF GPVAREVR-YKNFMKIVSLAPEVLMA-L--HNLQPAPGS-THKTKRVG-RGQGSGM-GKTATRGQKGQKSRTGYS-Q--- -KRGF-E-GGQQPLQRRLPK-IG--FTSINVDKVITMETIRSVYKLPKVK---------LIG--------S--------- SVQEIVSKIKDDNISYSGQK-K---QQK--GRN---RGKA-YNGNSLAFG----------TIGIKAL--EHGRIDSRQIE AARVAMTRKV------KRTGKIWIRVFPDKPLTKKPLETRMGKGK---------GSVEKWVMNIKP-GRIIYEM--AG-- VEESLAREALDLARYKLPFKTKI-VKNRLRIKRKRRVRGKI---TGSADRPRVSIFKSNRHFYAQAIDD---T--KGHTL AYSD---GAKL---------GVK-VNKEDVKKVAEDLAGK--LKALN-IETIVFDRNGYLYH--GVVASFADALRENGIK F---------------------------------------------------------------M-SKAVLRFIRLSPTK ARLIAREVQGMNAEEALAALEFM---------------------------------PNKAAKVISKVITSAVAN----G- -----GYEPEEVVITSCRVDRGPYLKRFRPRARGRASRIMKPTSHVYVEVAQKFKIKKGDIVEIIAGD------DK-GKT GEVLQVLPKKE--AVI--VAGCKVVKKAVK----PS--EQ-HPE-GGFINKEMPIHISNVR------------------- -------KV-------------EGGAS-----------------MGQKVNPIGLRLG--IN-RNWESRWFP------DFN K--MPERVEEDNKIRKFL--KKELY-----YAGISNIIIERTA-K-KLRVTIVAARPGIIIGKKGADIEKLKQKLQKLVF INIKEEKR---PQASAQLAAENVATQLERRVAFRRAMKKVIQAAQKA-GVKGIKVQVAGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEAHTTYGVIGVKVWIF-MVNDIIADSITRIRNASIRGQEVTKL-LYSKIVEAIVKILQEKGYIESYK VVE----E---G----NKKFINVVLKYEEAGKKK-------R---PVINEIKRISKPGRRIYKGKDEIKRFKNGYGTIIV STSKGVLPNDEAYRLGVGGEVLCSVW--MEKIRLKLRAYDHRVLDRSVSAIVEAVKRTGAEIRGPIPLPTKIRRYTVLRS PHINKDSR-EQFEIRIHSRLIDIVSATPDTVDSLMKLDLAPEVDVEVRSKRVIQGKVVKKSGDKTVSLLVERKVVHPKYH KIVKRFKKYLVHDEH--NKAKVGDIVTAVECRPISKRKSFRLKEIVQAG------------------------------- -MARSI-KKGPFVDD-HLMKKVLKAKE---SGDKK----PIKTWSRRSTIVPEMIGLTINVHNGRQFVPVYITE-NHVGF KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >EPSI_Sulfurovum_sp_NBC37-1 Concatenation of 2 sequences MAIKTYKPTTPSRRYMTNLDSGD-ITA-------------KASVRALLKNLPRSAGRNSNGRITSRH-REAGAKKL---- YRIIDFK-R--NK-FGIEGTVATIEYDPYRNCRICLVNYV-DGDRRYILQPKGLNVGDKIMSAESG-LD-IKTGNTMKLK NIPVGTLVHNIELSPGHGGQIARSAGGYAQIMGR--DGKYVSLRLPSGEMRYVLGECLATIGTVGNEDFSNIVIGKAGRS -RHL-----GIR-P-QTRGSAMNPIDHPHGGGEGKT-N--SGRH-PVSP---WGMPTKGYKTR-K-KKASD-K-LIISKR --------------------------------------MEFIVEKIGMSRTV---DVP---------SVPVTLLKVVDTK VCEVK-----------E--DG---KAL-VAY-------NS---LNK----------SIEGQQK----------------- ---FGVSKEFNKFMTIEV--------AEGTEA----------GDLNPAA------LAEAAAVKTSLNTKGRGFSGGMKRH NFGG-GPGSHGH-RFGRR-IGSIGNA-EWPG-RVQKGKKMPGQYGNTKVTVKN-DVVSFDAENG---------------- ----------ILVLKGS-IPGHNGARGLVR--MKTTVIK---------TTDLPKAFL-------EV-HPHNLYLYCKAYA SGLRANTAQTKNRSA--------VS-GGGKKPW---------AQKGGGRAR--------AGS---LR-SP----IF---- VGGGVAFGPS-TNKNYDQKVNKKQKKLALYHALAELAANE----------------R-LFVVDNV----AIE-S------ --GKTKLVV--KEMID--D---KTFLAFRNLQNAY-L---------------VEANELNAYLAAAYHS----VVIEKAVF DKLTSRMKQKY-NDI----VPALREECGVQNTMQTPKLEKIVISVGAG-EEGRDSKLIANMADTISLIAGQKAVIVNAKK SVAGFKAREGAPSGIRVTLRGDNMYNFFDKLVSIALPRVKDFRGTPR-KGFDGRGNYNFGLQEQLMFPEVE-----FDNI IKTHGMNITIVTS-----------------------TEDDKQAFTLLEKLGMPFMSRIG-K--RPVTVPSGIEVS-L--- -D-G-----TTLVAKKGNLEKRL-ETHGR--VGINIDG-SE--VTF----T-R--VGDKQDA-AFWGTYRALFNNIMVGL DKGYSKSLEINGVGY--RAAVEG-KT--LKLQ--LGFSHDVNFEI-P-E-GLDIKVD--K-N-IITVSG-TDKQAVGQAA AEIRAYR------PPEPY---KGKGVKYTDEVIIRKAGK----------MIQGFTRLNVADNSGAKEIMCIKVLG-SKRR Y--ASVGDVIVASVKKALPT-G-------KVKKGKVVKAVVVRTKKEIQRENGSLIRFDDNAAVIID-DKKE-PIGTRIF GPVSRETR-YAGFMKIVSLAPEVWMG-L--HNLQPAPGS-TRNRKRVG-RGQGSGT-GKTAGRGNKGQKARSGYS-K--- -KRGF-E-GGQMPLYKRLPK-VG--FTSINVEKIITLESIASV-HKLQVK---------LIG------------A----- SAKDLAPKIKDDAVTTSGK--K---QQK--GRN---RGKS-FRGNKIEFG----------DIAIKAV--EAGRIDSRQIE AARITMTRKI------NRTGKTWIRVFPDKPLTAKPLETRMGKGK---------GAVDRWVMNIKP-GRIIFEM--AG-- VEEELARAALTLAIHKMPFKCKI-IKNKLRAQRKARVKGKI---FGTAELPRLTVYKSNKHFYAQAIDD---N--AGATL ASAD---GRKL---------GLG-ANREDVKKVAAEMAKN--LASAN-IETVVFDRNGYLYH--GVVASFADALREAGIK F---------------------------------------------------------------M-SRALLKFVRVSPTK ARLIAREVQGMNAELALASLEFM---------------------------------PNKAAGIISKVIASAVAN----G- -----DFEPEEVEITSCRVDKAAVMKRWRPRARGTASRIIKPTAHILVEVGPKFKIKKGDQVMVIAGD------DK-GKT GEVLQVLPKKE--AVI--VAGCKMAKKAIK----PS-EQN--KE-GGFANAEMPIHISNVK------------------- ------------------------KVE--------A--------MGQKVNPIGLRLG--IN-RNWESRWFP------A-K E-RTADFIAEDYKIRKFL--KKELF-----YAGVSNIIIERTA-K-KLRINIITARPGIIIGKKGADIEKLKTTLVKMVA INIKEEKR---PQASGQLAAENVATQLERRVAFRRAMKKVIQGALKS-GAKGIKISVSGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEAQTTYGIIGIKVWIF-MMTDIIADSLTRIRNAAQRRLDVTTL-LHSNTIEATVAIFVDKGYLESYK VKE----D---G----NKKTIKVVLKYD---DNE-------K---SVINEIKKISKPGRRVHQGKDEIRTFKNGYGTLVV STSQGVLANDEAYKRGIGGEVICSIW--MEKIRLKLKAYDHRVLDRSVAAIVDAVKRTGAEIRGPIPMPTKMKRYTVLKS PHVNKDAR-EQFEIRIHGRMIDIVSATSDTIDSLMKLDLAPEIEVEIRSKRQITGTVIKKAGDKTATVLVERRVLHPRYH KTVKRFKKYLIHDEK--NEINVGDTVTAIECRPLSKTKSFRLLEIVKRG------------------------------- -MARST-KKGPFIDG-HLMKKVLAAKE---AGDKK----PIKTWSRRSVIFPEFIGLTINVHNGRQFIPVFITE-NHVGY KLGEFAPTRTFKGHK------G-SVQK----KVG-------- >EPSI_Thiomicrospira_denitrificans_ATCC_33889 Concatenation of 2 sequences MAIKSYKPTTPSRRFYTNVENND-ITS-------------KPSVRSLLVKLPASAGRNNNGRITSRH-REAGAKKL---- YRIIDFK-R--DK-FGIAGTVSTVEYDPYRNCRIALITYV-DGEKRYILLPKGLNVGDAIIADATG-VD-IKPGNAMKLM NIPVGTSVHNIELKVGKGGQMVRSAGTSAQIMGR--DGKYVSLRMPSSEMRLVLGECMATVGAVGNEEYINIVLGKAGRT -RHM-----GIR-P-QTRGSAMNPIDHPHGGGEGKT-N--SGRH-PVTP---WGKPTKGSKTR-R-KKASD-K-LIITRR --------------------------------------MEYIVEKIGMSRTITVP------------SKPVTLLRVLDAK VCEVN-----------E-------NSAIVAY-------KS---MNK----------AIEGQQK----------------- ---YSISSEFNRFVTLEV---------ANSEA----------GDIDLTP------LAEAKVIKATFTTKGRGFTGAMKRW NFSG-GPAEHGH-RFGRR-TGSIGNA-EWPG-RVMKGKKMPGQYGNTQNSVKN-EIISFDAENK---------------- ----------IIAVVGS-VSGANGSLGRVK--MSAIVLN-EKMEKA-SELALPESFS----GI----NPHNLYLYVKSAQ AAMRANSASALTRAE--------VR-GGGKKPW---------AQKGGGRAR--------AGS---RR-SP----VF---- VGGGKAFGPK-NNRNYDLKVNKKQKKLALNFALNEHAQKG----------------S-LFIVDSI----EIA-S------ --GKTKLFV--KTVLD--E---KTYLAFENIASTY-V---------------IEENELNAYLAANYRS----LVIEKAVW ENLVARMKDKY-LAL----KAELQADLGIKNPMQTPALEKIVISVGAG-FAMKDNKLIQNIEDTITTIAGQKASTVIAKK SVAGFKVREGMPVGVRVTLRGEKMYNFFDRLVSMALPRVKDFRGVPR-NGFDGRGNYNFGLQEQLIFPEVS-----YDSV MQIHGMNITVVTS-----------------------AESDKAGFALLEKMGMPFMSRIG-K--LPVEFAADVKVS-A--- -N-G--N-VITFVKGKNSVDLDT--KG-N--VAFNIDG-NV--ITF----A-T--LSDRTHR-AFWGTYRALAANIVTGL TTGYTKQLEINGVGY--RASANA-NV--LNLQ--LGYSHDINYNL-P-E-GVEAVVE--K-NV-ITLKS-HDKQALGQVA AEVRGFR------PPEPY---KGKGIKYSDETIVRKAGK----------MIQAFTRLNVADNTGAKEVMCIKVLG-SKRR Y--AQVGDVIIASVKKATPT-A-------KVKKGKVVKAVIVRTAKEIHRENGSLIRFDDNAAVILD-DKRE-PIGTRIF GPIAREVR-YSGFMKIVSLAPEVVMG-I--ENLTPAEGS-TANRKRVG-RGCGSGM-GKTSTRGGKGQTARSGSS-R--- -KRNF-E-GGQTPLARRLPK-IG--FTSINVEKIITMESIRGV-HKIAVK---------LVG------------A----- SAKDLASKIKDDNVTATGK--K---MMK--GRN---RGYA-RSGYTLAFG----------DIALKAV--EAGRINSRQIE SARISATRHI------KRNGKIWIRVFPAKPLTAKPLETRMGKGK---------GSVDQWVMNIKP-GRIIFEM--AG-- VPEELAREALTLALHKLPFKTKI-IKIANRLKRKRRIRAKI---SGCASLPRVSVFRSNRYLSVQAIND---A--TATTL TSLS---SKAT---------GHK-ANKEGGAALGAAFAAK--LKEVG-ISQIVFDRNGYQYH--GVIAAFGDALRENEIK F---------------------------------------------------------------M-ARALLKFIRVSPIK SRLIAREIQGMNAELALASLEFT---------------------------------PNKAAKIIAKVVASAVAN----S- -----GNEAADCIVTSCRVDNGPVLKRFRPRARGMASGIRKPTAHILVEVEGKFKFKKGDTVEIIAGD------DR-GTK ATVLAVLPKKN--KVI--VEGCKIVKKAIK----PT--EE-NTK-GGHLNKEMPIDVSNVR------------------- ------------------------KVE--------A--------MGQKVNPIGLRLG--IN-RNWESRWFP------NFK T--AAAYLGEDHKIRTYL--KKELY-----YAGVSNIVIERTA-K-RLRVTIIAARPGIIIGKKGSDIEKLKDTLQALLS VNIKEEKK---AQISSQLVAENVATQLERRVAFRRAMKKVMQNAQRG-GAKGIKVSVSGRLGGAEMARTEWYLEGRVPL- -HTLRAKIDYGFAEAHTTYGCIGVKVWIF-MINDLVSDALTRIRNAGMRRLDVTTL-VHSKSVEALANILVEKGYIESCN VVE----D---G----VKKTINVVLKYS---DNG-------K---SVINEMKRISKPGRRVYKGKDEIKRFKNGYGTIIV STSHGVLPNDKAYALGVGGEVMCTVW--MEKIRLKLKAYDHRVLDRSVASIVEAVKRTGAVIRGPIPLPTKIRKYTVIKS PHVNKSSR-EQFEIRMHARVIDIVSATPETVDSLMKLDLAPEVDVEVRSKREIQGNVVKISGDKTASIVVERRVMHPRYH KVVKRFKKYLVHDER--NELKVGDEIVAIECRPLSKTKSYRLKSVVVGV------------------------------- -MARSV-KKGPFVDD-HLMKKVLSAKA---EGSKK----PIKTWSRRSMVLPDMVGITFNVHNGRQFVPVYVTE-NHIGY KLGEFAPTRTFKGHK------G--SVQ----KKG-------- >EPSI_Wolinella_succinogenes_DSM_1740 Concatenation of 2 sequences MAIKTYKPYTPSRRFMTGLSSSD-ITS-------------KPSVRSLLMKLPVTAGRNNNGRITSRH-KEGGAKKL---- YRIIDFK-R--NK-FNIEGTVSAIEYDPYRNCRIALVTYK-DGEKRYIIQPTGLAVGDLVISAEGG-LD-IKTGYAMKLK NIPIGTIIHNIELHPGAGGQLARSAGASAQIMGR--EGKYTIIRMPSGEMRYILEECMATIGTVGNADFANISIGKAGRN -RHR-----GIR-P-QTRGAAMNPVDHPHGGGEGKT-G--SSGH-PVSP---WGMPAKGFKTR-K-KKASD-K-LIISRR ----------------------------------M---E-FLVEKIGMSRTI---SVP---------STPVTLLKVKDAK VCEVL----G---------NGK--ALVAYAQ-------GK--DANK----------AIEGQQK----------------- ---YNLSKEFNRFATLEVE-----------------------AG-DQDV--A-P-LAQAVRVKVSLQTKGRGFTGVMKRW NFAG-GPAAHGH-RFKRR-TGSIGNR-EWPG-RVQPGKKMAGQYGNEKVTVQN-EIVSFDAENK---------------- ----------ILVLKGS-IPGFNGAFGRIK-MSKAIILN-NELQKN-GEVALPERFK-------EI-HSHNLYLYVKSYL ASLRANSAKAKKRGE--------VS-GGGKKPW---------SQKGGGRAR--------AGS---IT-SP----VF---- VGGGVSHGPS-NNRNYDLKVNKKQKKLALQYALMEKAEQG----------------K-LYVVDSL----QVD-S------ --GKTKLFV--SQISD--E---KTFLAFRNLKECY-L---------------ADANELNAYLVAAFRS----VVIEKSLF ENITYQLKKLYNEEL----KAKLSEELGIKNPMLLPKLEKIVISVGAG-DHAKDTKVMQNIADTISLIAGQKAVITIAKK SVAGFKMREGMPMGVKVTLRGNQMYNFLEKLISIALPRVKDFRGVPR-NGFDGRGNYSFGLNEQLMFPEVV-----YDDI MVSHGMNITMVTT-----------------------TNNDKEAFKMLELFGMPFMSRIG-K--RPISIPSGVDAK-I--- -E-G-SK-IVFTKGKQEKVLETY--GR----VGLEIAN-GE--LVL----K-L--GGEAQSK-AYWGTYRALANNIVIGL SAGFTKQLEINGVGY--KAAVKG-SV--LELA--LGFSHPVNYEI-P-E-GVEIAVE--K-N-VITIKG-SDKQQIGQIA AEIREFR------PPEPY---KGKGVKYSDETIIRKAGK----------MIQSFTRLTVADNSGAKEVMCIKVLG-SKRR Y--ATVGDVIIASVKKALPN-G-------KIKKGQVVKAVVVRTKKEVQRDNGSLIRFDDNAAVILD-NKRE-PVGTRIF GPVGREVR-YANFMKIVSLAPEVLMA-L--ENLKPAQGS-TKDRKRVG-RGQGSGM-GKTSTRGGKGQTARTGYK-A--- -KRGF-E-GGQQPLQRRLPK-VG--FTTINVEKIITLDSIASV-HKFPIK---------LIG--KGA---S-ELA-SKI- KDERITT---------SGRA-K---QMK--GRN---RGKS-FRGNSLAFG----------DIGIKAT--EHGRIDSRQIE AARIAMTRHI------KRAGKIWIRVFPDKPLTAKPLETRMGKGK---------GSVDKWVMNIQP-GRIVYEM--AG-- IEEELAREALALAQSKLPFKTKI-VKNALRAKRKLRVRGKI---FGTAQKPRVSLFRSNRYLYAQAIND---E--SGLTL ASVD---GKKL---------GLG-NNKEEAKKIAASFAAS--LQEAG-IKEVVFDRNGYLYH--GVVASFADSLRENGIG L---------------------------------------------------------------M-SKALLRYIRLSPTK ARLVAREVQGMNAELAIASLEFM---------------------------------PNKAAKVISKVIASAVAN----G- -----GMGAENAVVKSCRVDAGPVLRRFTPRARGRATPIRKPTSHVFVEVVEKFQIKKGDKVQVIAGD------DK-GKV AEVIKVMPKSS--QVI--VAGCKVAKKSVK----PS--EQ-NPK-GGFVNKEMPIHISNVK------------------- ------------------------KVE--------A--------MGQKVNPIGLRLG--IN-RNWASRWFP------NYQ T--APLNISEDHKIRKFL--KKELY-----YAGVSEIIIERTA-K-KLRVTVVAARPGIIIGKKGADIEKLKEALKKIIS INIKEVKR---PQANAQLAAENVTMQLERRVAFRRAMKKVMQAAMKA-GAKGIKIKVSGRLAGAEMARTEWYMEGRVPL- -HTLRAKIDYGFAEAMTTYGIIGAKVWIF-MVNDIIADSLTRIRNAAMRRLDYTTL-YYAKIVVSILEVFLAKGFIESYK VID----K---D----GKQSINVVLKYD---EKG-------R---SVISEIKRISKSGRRVYKGRDELKRFKNGYGTIVV STSKGVIGNEEAYKANVGGEALCSIW------------------------------------------------------ -------------------------------------------------KRVIQGKVVTKAGDKSVTILVERRVTHPKYR KIVKRFKKYIVHDES--NAVKVGDMIEAIECRPLSKRKSFSLHKVLSVG------------------------------- -MARSI-KKGPFIDD-HLMKKVLKSKE---TKDNK----PIKTWSRRSTIVPDMIGLTLNVHNGRAFVPVYVTE-NHVGY KLGEFAPTRTFKGHK------GSVQKK----IGK-------- >FIRM_Alkaliphilus_metalliredigens_QYMF Concatenation of 2 sequences MGIKKFRPTSPGVRQMTVSTFEE-ITKV------------DP-EKSLLTPLSKSGGRNAHGKITVRH-RGGGLKRH---- YRIIDFK-R--NK-DDIPAKVASVEYDPNRTANIALLHYV-DGEKRYIIAPKGLKVGEMIFSGP-E-SD-IKVGNALPLI NIPVGTIIHNIEMKPGKGGQIARSAGNSAQLMAK--EGRYALVRLPSGEVRQILIECRATIGQVGNLDHENVTIGKAGRK -RKM-----GIR-P-TVRGSAMNPNDHPHGGGEGRS-P--IGRPSPVTP---WGKPALGYKTR-KKNKHSD-K-FIVTGR ---------------------------------MK---G-LMGRKVGMTQIFN-EDGI---------VTPVTVIEVAENV VTQIK----SDE----T--DGY--NSVQVGY-------GE--KTIK----------PLQGHFK----------------- ---AG-TTPKRTMKEFRV--------DSTEGF-----TA---GQ-ELKA--D-L-FQAGDKVDVTGISKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGAS-AYPG-RVFKGKNLPGHMGNVQVTAQNLEIVRVDLEKN---------------- ----------LLLIKGA-VPGPKKGVLVIQ-MPKVAVYN-VSGQKV-SEMELSENIF----GV-EV-NEHVLYEAVKNQL ANKRQGTQSAKTRAE--------VR-GGGRKPW---------KQKGTGRAR--------AGT---IR-SP----LW---- IGGGTVFAPK-P-RDHSYTLPRKVKRLALKSALTSKVNNE----------------E-LLVLDEL----SLD-T------ --PKTKLLV--VGEKN--E---AIIKSASNIPGVT-T---------------ALVNTINVYDILNHDK----FIITKDAV EKVEARIKDKYRNEV----APAMMEKFGYKSVMQIPRLEKIIINMGLG-QAKENQKELEIAVKELGIIAGQKPITTKAKK SVANFKVREGMAVGAKTTLRGEKMYEFADRLINIALPRVRDFRGVNP-NSFDGRGNYALGVKEQLIFPEIE-----YDKV DKVRGMDIILVTT-----------------------ANSDEESRELLRLLGMPFMSRIG-L--KPIEVPQGVEIT-V--- -D-E-KN-IVTVKGPNGQLSEKI--HR-D--ITVETEA-NV--INV---VR-P--TENKKHK-SLHGLSRTLVANMVEGV TKGYEKKLELVGVGY--RATMQG-KK--LVLS--LGFSHPVEIDQ-P-E-GLTIEVP--S-QTQVTVKG-IDKQQVGNFA AKIREYR------KPEPY---KGKGVRYAGEVVRRKEGK----------MIQQESRLKVADNSGAKELLCIRVLG-TRRR Y--ANVGDVIVCSVKSATPG-G-------VVKKGEVVKAVVVRTVSTTRRKDGTYIKFDENAAVIIK-DDKQ-MVGTRIF GPVTRELR-DRDFMKIVSLAPEVLMK-L--HELKPAKGA-VKEVKRKG-RGRATGN-GKTAGRGHNGQNSRSGGG-V--- -RIGF-E-GGQMPLARRLPK-RG--FTNVNVDVLITPEFLKEM-GVIKVK---------ILG--NGN-L-E-K-N-LTI- KAQKFTKSAAEKIEAAGGKA-R---VHR--GRM---TGQA-TKGNKVTYG----------EYGLMAL--EPAWITSNQIE AARIAMTRSI------KRGGKVWIKIFPHKPVTKKPAETRMGAGK---------GSPEFWVAVVKP-GRIMFEL--AG-- VPEDKAREALRLAMHKLPIKTKF-VKNTNRQGRHQRVRNKI---TGTSQRPRLNVYRSLNHIYAQVIDD---V--AGITL VAASTL-DEAI-KSQV----EAS-GNQDAAKLVGELVGKR--ALEKG-VSTVTFDRGGYIYH--GRVKALADGAREAGLK F--------------------------------------------------------------ME-ARAIAKFVRIAPRK VKIVVDLVRGKQVDEALAILKHT---------------------------------PKGASPVVIKLIQSAVAN----A- ENNH-EMDREQLFVSEVYANQGPTMKRFRPRAMGRATTIRKRTSHIGIVVKE-MHVKKDDIVVVISGK------DK-GKK GKILHAIPKKE--RII--VEGVNMVTKHQK----PT--QQ-SQQ-GGIIKQEAAIHVSNVL-LWDKKA-------NQ--G --VRAGHKV---LE--------NGKVR---VSKKTG---EVL--MGQKVNPHGLRVG--VI-KDWDAKWYA------NKR D--FSDYLIEDHSIRKFV--KKKLF-----LSGINKIETERAANN-RVKINVHTAKPGMVIGKGGIGVEELRKELEKMVI VNVVEVKR---PEVESQLVAENIAFSLERRVSFRRAMKQAMQRAMRA-GAKGIKVSTAGRLGGADMARTEGYSEGNVPL- -HTLRADIDYGFAEADTTYGKLGIKVWIYMTMTDPIADMLTRIRNASAVKHDTVDV-PASNMKKDIANILLNEGFIKGFD VIE----D---G----KQGILRLQLKYG---QSK-------E---RVITGIKRISKPGLKVYAKRDEIPRVLGGLGIAII STSKGITTDKVARKEGVGGEVIAYIWKANQKIRIRLKGYDHKAVDQSAEKIVATAKKSGAEVSGPIPLPTEKQIITILRA VHKYKDAR-EQFEMRTHKRLIDILSPTPKTVDLLMRLDLPAGVDIEIKLRKTRVGRVVSDKMDKTVVVLVEDFVRHPLYG KAMKRTNKFKTHDEL--NECGIGDKVKIMETKPLSKDKRWRLVQIVQKA------------------------------- -MSRSA-KKGPFIHK-GLLRKIEEMNE---KDEKK----VIKVWSRASTIFPQMIGHTIAVHDGRKHVPVYVTE-DMVGH KLGEFALTRTYRGHD------D--DEK----TSK------RK >FIRM_Alkaliphilus_oremlandii_OhILAs Concatenation of 2 sequences MAIRKLKPTSPAKRQMTVSTFEE-ITTN------------QP-EKSLLEPIKNSGGRNSYGRITVRH-RGGAQKRH---- YRIIDFK-R--NK-DGVPAKVATIEYDPNRSANIALLHYV-DGEKRYIIAPQGLKVGDMVESGP-N-AD-IKTGNALPLA NIPVGTMIHNIEMKPGKGAQLVRAAGNSAQLMAK--EGKHALVRLPSTEVRYLPIDCKATIGQVGNQEHENITIGKAGRK -RNM-----GIR-P-TVRGSAMNPNDHPHGGGEGRT-S--IGRPAPVTP---WGKPALGYKTR-DSKKASN-K-MIVSRR ---------------------------------MK---G-LVGRKIGMTQMFD-ETGL---------VIPVTVIEVEANA VTQVK----TIE----K--DGY--NAIQVGY-------GQ--IVNK----------PSKGHFK----------------- ---AG-VTPKRSLQEFRL--------ESTEGF-----TA---GQ-ELKA--D-L-FKAGDKVDISGVSKGKGFQGVIKRH NQSR-GPMAHGS-RYHRG-PGSMGAA-SYPS-RVFKGKKLAGHMGHENVTIQNLEVVKVDVERN---------------- ----------LLIVKGA-VPGPKKGLLTIN-MPKVAIYN-VSGQQV-SEIELSENVF----GV-EV-NEHAMYEVVKNQL ANRRQGTQSAKTRAE--------VR-GGGRKPW---------KQKGTGRAR--------VGS---IR-SP----LW---- VGGGIVFAPK-P-RDYSYTIPKKVRRLALKSALTSKVNSN----------------E-LIVLDEL----KLD-A------ --PKTKLIV--MGEKS--E---AVIKSANNIQGVQ-T---------------ALVNTINVYDILKYDK----LIITKDAV QKVEARLKDMYKSEV----APAMMEKFGYKSVMEIPKIEKIVVNMGLG-DSKDNPKGLEAAVKELGIITGQKPVVTRAKK SVANFKLRQGMPIGAKVTLRGEKMYEFADRLLNIALPRVRDFRGVNP-NAFDGRGNYALGIKEQLIFPEIE-----YDKV EKLHGMDIIFVTT-----------------------AKTDEESRELLKLMGMPFMSRIG-L--RPIEIPQGVEVK-I--- -D-E-KN-FAVVKGPKGTLEQQL--SK-D--MEIKIEE-NV--INV---VR-P--TDNKKHK-SLHGLTRTLLSNMVEGV TKGYEKKLELVGVGY--RANKQG-DK--LVLT--LGFSHPIEMVD-P-E-GITVEVP--S-QTEIFVKG-INKQVVGNYA AKIRELR------KPEPY---KGKGVKYANEVIRRKVGK----------MIQQESRLKVADNSGAKELLCIRVLG-TRRK Y--AHIGDVIVCSVKSATPG-G-------VVKKGQVVKAVVVRTTNTTRRKDGSYIKFDENAAVIIK-DDKQ-PTGTRIF GPVARELR-DKNFMKIVSLAPEVLMK-L--HELRPAEGA-VRDRKRKG-RGTASGL-GKTAGRGSNGQKARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNINIDRLVTAELLKET-GVIKIK---------ILG--NGN-L-E-K-S-LTV- QAQKFTKSAIEKIEAAGGKA-R---VHR--GKM---RGQA-HKGNTISYG----------EYGLMAM--EPAWITSNQIE AARIAMTRYI------KRGGKVWIKIFPHKPVTKKPAETRMGAGK---------GSPEYWVAVVKP-GRVMFEL--SG-- VSEERAREAMRLAMHKLPIKCKF-VKNANRLSRHQRVRNKI---TGTPERPRLNVYRSLTNIYVQLIDD---V--AGKTL VAASSL-DKEI-KDQV----SAT-GNAEAAKLVGQLVGKR--ALEKG-IDTVTFDRGGNIYH--GRIQALAEGAREAGLK F--------------------------------------------------------------ME-AKAIVRYVRIAPRK AQQVVDLVRGKKVDEALAILKYT---------------------------------PKAAAPIVEKLVKSAVAN----A- ENNN-GMDIDRLYISEIYANQGPTMKRFRPRAMGRATTIRKRTSHIEVVLKE-MHVKKGDTVVVITGK------DK-GKK GKVLQVLPKKN--RVI--VEGVAMVTKHQK----PN--QQ-MQQ-GGRIEQEAAIDASNVM-IWDKKA-------NQ--G --VRVGYKL----E--------NGKVR---VSKKTG---EVI--MGQKVNPHGLRVG--II-KDWDTKWYA----N-K-R D--FGDLLVEDNEIRKFV--KKKLF-----LSGVSRIEIERAANN-KVKVNVHTAKPGMVIGKGGQGVEDLRKDIEKIVA VNVIEVKR---PETDAQLVAENVAFQLERRVSFRRAMKQVMQRAMKS-GAKGIKVATSGRLGGAEMARTEGYSQGNVPL- -QTLRADINYGFAEADTTYGKLGIKVWIYMTMTDPIADMLTRIRNGNMAKHETIDI-PASNMKKEIANILLEEGFIKGFD VIE----D---G----KQGIIRMQLKYG---KNK-------E---KVITGIKKISKPGLRVYAKKDEIPRVLGGLGIAII STSRGIITDKVARKEGVGGEVIAYIWKNNQKIRIRLKAYDHMALDQSAEKIVETAKKSGAEVSGPVPLPTEKQIITILRA VHKYKDSR-EQFEMRTHKRLIDILNPTPKTVDALMRLDLPAGVDIEIKLRKTRVGRVVSDKMDKTITVLVEDFVRHPLYG KAVKRTKKFKAHDEM--NECRIGDRVRIMETKPLSKDKRWRLVQIVEKA------------------------------- -MSRSL-KKGPFIHQ-GLLKKIEEMNA---KNEKK----VIKTWSRASTIFPQMIGHTIAVHDGRKHVPVYVTE-DMVGH KLGEFALTRTYRGHD------D--NEK----TTK------RK >FIRM_Anaerocellum_thermophilum_Z-1320,_DSM_6725 Concatenation of 2 sequences MGIIVYKPTSPGRRNASVLNYKEIITKT------------EP-EKSLVFTEKKWAGRNNQGRITVRH-RGGGHKKK---- IRIVDFK-R--DK-DGIPAKVEAIEYDPNRTAFLALLCYA-DGERRYIIAPEGLKVGDTVMSGP-D-AD-IKVGNALPLK NIPVGTMIHNIELMPGKGGQLCRSAGSVAQLMAK--EGKYALIKLPSGELRYVSQECRATIGQVGNLDHENVRIGKAGRK -RWM-----GIR-P-TVRGSAMNPVDHPHGGGEGKA-P--IGHPGPLTP---WGKPTLGYKTR-KKNKPSD-K-FIVKRR --------------------------------MTK---G-ILGKKIGMTQIFD-EAGR---------AIPVTVIEAGPCV VVQKK----TVE----K--DGY--SAIQVGF-------ED--ILNK----------PLRGHFK----------------- ---HG-VKPKRFLRELRL--------KDADKY-----EV---GQ-EIRV--D-I-FQPGEKVDVTGISKAKGFQGVIKRH GQQR-GPMSHGS-MYHRR-VGSMGSN-TFPA-RTFPGKKMPGRMGGERVTVLNLQVVKVDPDRN---------------- ----------LLLVKGS-VPGNKNSLLIIR-MAKVPVYN-IEGQQI-GEIELNDSIF----NV-PI-NTHVLHQAVVAHL ANRRQGTFAAKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----TW---- RKGGVVFAKK-P-RDFSIDLPKKVKRLALKCALSSKVKEN----------------N-LIVLDRW----DMN-Q------ --YKTKLIV--IPEKN--E---YLQKSTKNIPEVK-T---------------LQVGNLNVFDILKYDK----FVILQDAV KKVEPRLKEKYFQEV----VPAMMQKFGYKNVMQVPRLAKIVVNIGLG-EGKDNPKAMEAAVNDLMAITGQKPVVTRAKK SIANFKLRKGMPIGCMVTLRGDRMYEFLDKMINLALPRVRDFRGVSD-KSFDGRGNYSIGFKEQLVFPEID-----YDKV DKIRGLEVTIVTS-----------------------AKTDEEAKELLRLLGMPFMSRIG-R--KPIDIPSGVDVK-I--- -D-G--N-VITVKGPKGTLTREI--HP-E--MIVKIEN-NQ--IIV---QR-P--SDERFHK-ALHGLTRTLIANMVEGV TKGYEKVLEVVGIGY--RAQKQG-KK--LVLN--VGYSHPVEIEE-P-A-GITIEVP--D-QNRIVVKG-IDKQQVGNFA ANIRKVR------EPDPY---LGKGIKYADEVLRLKEGK----------MIQPQSRLKVADNTGAKEVMCIRVLG-SNRK F--ANIGDVIVCSVKDATPG-G-------VVKKGDVVKAVIVRTRKGVRREDGTYIRFDDNAAVLIR-EDGT-PRGTRIF GPVARELR-DKDFMKIVSLAPEVLMK-L--YELKPAPGS-KKNRKRVG-RGESSGH-GKTSTRGHKGQWARSGGG-V--- -RPGF-E-GGQMPLTRRIPK-RG--FKNVNVEKLITPELLLKE-RVISVK---------ILG--RGE-L-T-K-R-LIV- RVQKVSEGARKKIEASGGKV-K---QQR--GRM---KGKA-TRGNFVAYG----------DFGIMAL--EPGWITSNQIE AARVAIARHI------KRGGKVWIKIFPDKPVTRKPAETRMGSGK---------GSPEYWVAVVKP-GRVMFEV--GG-- VDEEVAKEALRLAIHKLPIKCKI-VRNEKRLIRHKRIRKKV---FGTSERPRLCVYKSLKYIYAQIIDD---E--KGHTL VAASSL-EPEI-KSRL----SST-KSIEAAEYVGKVIAER--AKEKG-ITKVVFDRGGYPYH--GRVKALAEAARQGGLE F-------------------------------------------------------------VKK-ATATLRYAMISPRK VRVVIDLIRNKPVNEALNILKFL---------------------------------PKRAARIVEKLVKSAIAN----A- ENNH-NMNVDKLYIAEIYANGGPMLKRIRPRAQGRAFLIRKRTSHITVVLKEKVHVKKGDTVVVISGK------YK-GKQ GKVLTVLPKDK--KVV--VEGVNIVKKHVR----PN--PK-MPQ-GGIITQEAPIWACKVM-LVCPKC-------GK--P --TRIGHRF---IQ--------EGKVR---ACKKCG---EII--MGQKVHPKGFRLG--II-RDWDSRWFA------NDK D--FEKYVLEDYKIRRHI--KEKLY-----NAGISRIEIERAA-K-RVKVIIHTAKPGIVIGRAGSGVEALRKELEKLIS LDIKEIKV---PELDAQLVAENIAAQLEKRVSFRKAMKQAMARALRS-GAKGIKTMVSGRLGGADIARTEWYKEGRIPL- -QTLRADIDYGFAEAHTTYGRIGVKTWIYMYVIDPIADMLTRIRNANNARHEIVDI-PASKMKKAIAQILLEEGFIKDYE IID----D---G----KNGIIRIRLKYG---PNK-------E---RAITGLKRISKPGRRVYAGKDELPRVLGGLGIAII STSKGIMTDKKARKEGVGGEVLCYVWSKAQRMRIKLKSFDYKLLEQSAKKIVETAKNTGAEVSGPVPLPTDREVITIIRA PHKYKDSR-EQFEIKTHKRLIDIIKPTQKTVDALMRVELPAGVDIEIKLRKTRVGVVVSDKMDKTVVVAVERHVQHPLYK KTIKRTTKFKAHDEN--NECRVGDKVLIMETRPLSKEKRWRVVQILERA------------------------------- -MGRSL-KKGPYCDP-KLLKKIEKMNQ---NNEKK----VIKTWSRRSTILPQMVGHTIAVYDGRKHVPVYITE-EMVGH KLGEFAPTRTFKGHG------H-HTER----STA------LK >FIRM_Anoxybacillus_flavithermus_WK1 Concatenation of 2 sequences MAIKKYKPTSNGRRGMTVLDFSE-LTTD------------KP-EKSLLAPLKKKGGRNNQGKLTVRH-QGGGHKRQ---- YRIIDFK-R--DK-DGIPGRVATIEYDPNRSANIALIHYA-DGEKRYIIAPKNLEVGMEIMSGP-D-AD-IKVGNALPLA NIPVGTVIHNIELKPGKGGQLVRAAGTSAQVLGK--EGKYVLVRLSSGEVRMILATCRATVGQVGNEQHELVNIGKAGRA -RWL-----GIR-P-TVRGSVMNPVDHPHGGGEGKA-P--IGRKSPMTP---WGKPTLGFKTR-KKKNKSD-K-FIVRRR ---------------------------------MK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVIQATPNV VLQKK----TIE----N--DGY--EAIQLGF-------ED--LANK----------PQKGHAK----------------- ---AN-TTPKRFIREIRG--------VNLAEY-----EV---GQ-EVKV--D-I-FNEGEIVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--IAPN-RVFKSKELPGRMGGERVTVQNLKVVKVDPERN---------------- ----------LILIKGN-VPGPNKGLVIIK-MPKVALYN-QNGENI-GEIELNDAVF----GI-EP-NKHVLFEAVIMQR ASLRQGTHKTKNRAE--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPV-P-RSYSYKLPKKVRRLAIKSALSSKVLEN----------------S-IVVLDNL----TLE-A------ --PKTKLIV--TADAN--E---NVILSARNIPGVT-V---------------VTASGINVLDVLNHDK----LVITKAAV EKVENRLKEKYLKEV----VPALMSKFNYKSVMQVPKIEKIVINMGVG-DAVQNAKALDNAVEELALISGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGERMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV NKVRGMDIVIVTT-----------------------AKTDEEARELLTLLGMPFMSRVG-K--KPLEIPAGVTVT-L--- -N-G--N-TVTVKGPKGELTRTF--HP-D--MVIKVEG-NI--LTV---ER-P--SDEKHHR-ALHGTTRSLLANMVEGV SKGYERALELVGVGY--RATKQG-KK--LVLS--VGYSHPVEIEP-E-E-GLEIEVP--S-QTKIIVKG-ADKQRVGELA ANIRAVR------SPEPY---KGKGIRYEGEVVRRKEGK----------MIQQETRMKVADNSGAREVLVIKVLG-SGRR Y--ANIGDIVVATVKDATPG-G-------VVKKGQVVKAVVVRTKRGVRRTDGSYIRFDENACVIIR-DDKS-PRGTRIF GPVARELR-EKDFMKIVSLAPEVIMK-L--HELQPAPGS-RKERNRVG-RGIGSGN-GKTSGKGHKGQNARSGGG-V--- -RIGF-E-GGQTPLFRRLPK-RG--FTNVNLEALVTPELLLET-GVVSIK---------VLG--DGE-L-T-K-K-LTV- KAHKFSASAKEAIEAAGGTT-R---EHR--GRM---KGRA-KGGTEVHFG----------EYGLQAL--EPAWITNRQIE AARRAMTRYM------RRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVMFEI--AG-- VSEEVAREALRLASHKLPIKCKF-VKNAVRKKRHARVRRKV---VGTAERPRLNVFRSNKHIYAQIIDD---M--KAVTL VSASTL-DKEF-------DLEST-GNVEAAQKVGELIAKR--ALEKG-ITSVVFDRGGYLYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MQ-AKAVARTVRIAPRK ARLVIDLIRGKQVSEAVAILRHT---------------------------------PKAASPIIEKVLKSAVAN----A- EHNY-DMDVNKLVVTEAYVNEGPTLKRFRPRAQGRASAINKRTSHITIVVSE-MHVKKGDKVQVISGK------DK-GKQ GVILAAFPKKN--RVL--VEGVNIVKKHVK----PS--QA-NPQ-GGIINQEAPIHVSNVM-PLDPKT-------GL--P --TRVGYKV----V--------DGKVR---YAKRSG---EIL--MGQKVNPIGLRIG--II-RDWESRWYA------E-K D--YADLLHEDLKIREYL--TKRLS-----DAAVSRIEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKALNELVH INIVEIKK---PDLEAKLVAENIARQIENRVSFRRAQKQAIQRTMRA-GAKGIKTMVSGRLGGADIARSEHYSEGTVPL- -HTLRADIDYATAEADTTYGKIGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKREIAEILKREGFIRDVE YIE----D---N----KQGILRIFLKYG---PNN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIAIL STSQGILTDKEARQKRTGGEVLAYIWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKLRKVLVGRVVSDKMDKTITVLVETYKKHPLYG KRVKYSKKYKAHDEN--NVAKVGDIVKIMETRPLSATKRFRLVEVVEKA------------------------------- -MGRSL-KKGPFCDD-HLMKKIEKLNE---TGQKQ----VIKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYITE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTK------R- >FIRM_Bacillus_amyloliquefaciens_FZB42 Concatenation of 2 sequences MAIKKYKPTSNGRRGMTTSDFAE-ITTD------------QP-EKSLLAPLHKKGGRNNQGKLTVRH-QGGGHKRQ---- YRVIDFK-R--DK-DGIPGRVATVEYDPNRSANIALINYV-DGEKRYILAPKGIQVGTEIMSGP-E-AD-IKVGNALPLI NIPVGTVVHNIELKPGKGGQLVRSAGTSAQVLGK--EGKYVLVRLNSGEVRMILSACRASIGQVGNEQHELINVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRKSPMSP---WGKPTLGFKTR-KKKNKSD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVIEAAPNV VLQKK----TAE----N--DGY--EAIQLGF-------DD--KSNK----------PEKGHVK----------------- ---AE-TAPKRFVKELRG--------VDMDAY-----EI---GQ-EVKV--E-I-FSAGEIVDVTGVSKGKGFQGAIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VDPN-RVFKGKLLPGRMGGDQITVQNLEIVKVDAERN---------------- ----------LLLIKGN-VPGARKTLITVK-MPKVALYN-QNGSTA-GDIELNASVF----GI-EP-NESVVFDAILMQR ASLRQGSHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYSYKLPKKVRRLAIKSVLSSKVNDN----------------N-IIVLEDL----TLD-T------ --VKTKLIV--TADAN--E---AVSLSARNIPGVT-V---------------VQANGINVLDVVNHEK----LLITKAAV EKVENRLKEKYNKEI----SPALMTKFNYDSVMQVPKIEKIVINMGVG-DAVQNAKAIDSAVEELTFIAGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLISVSLPRVRDFRGISK-KSFDGRGNYTLGIKEQLIFPEID-----YDKV TKVRGMDIVIVTT-----------------------ANSDEEARELLTQVGMPFMSRVG-K--KLLEIPSGVTVT-L--- -N-E-GN-TVAVKGPKGELTRTF--HP-D--MEIKIED-NV--LTV---TR-P--SDHKEHR-ALHGTTRSLLGNMVEGV SKGFERGLELVGVGY--RAAKSG-NK--LVLN--VGYSHPVEIVP-E-E-GIEIEVP--S-QTKVVVKG-TDKERVGAIA ANIRAVR------SPEPY---KGKGIRYEGEVVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKQATPG-G-------VVKKGEVVRAVIVRTKSGARRTDGSYISFDENACVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVIMK-L--HELKPSEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQMPLFQRLPK-RG--FTNVNVDKLVTPELLLET-GVISVK---------ILG--NGK-L-E-K-K-LTV- KANKFSASAKEAVEAAGGTA-R---EHR--GKM---RGRA-KGGTEVHFG----------EYGIQAL--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVLFEI--SG-- VSEEVAREALRLASHKLPIKTKF-VKNAARQKRHARVRAKL---SGTAERPRLNVFRSNKHIYAQIIDD---V--NGVTL ASASTL-DKDL---NV----EST-GDSAAAAKVGELVAKR--ASEKG-VSDVVFDRGGYLYH--GRVKALADAAREAGLK F--------------------------------------------------------------MQ-AKAVARTVRIAPRK ARLVMDLIRGKQVGEAVSILNLT---------------------------------PRAASPIIEKVLKSAIAN----A- EHNY-EMDANNLVISQAFVDEGPTLKRFRPRAMGRASQINKRTSHITIVVSE-MHVKKGDKVMVISGK------DK-GKQ GTILAAFPKKD--RVL--VEGVNMVKKHSK----PT--QA-NPQ-GGISNQEAPIHVSNVM-PLDPKT-------GE--V --TRVGYKV----E--------DGKVR---VAKKSG---QVL--MGQKVNPVGLRIG--VI-RDWESKWYA------G-K D--YADFLHEDLKIREFI--SKRLS-----DASVSKVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKALNSLVH INILEIKR---ADLDAQLVADNIARQLENRISFRRAQKQQIQRTMRA-GAQGVKTMVSGRLGGADIARSEYYSEGTVPL- -HTLRADIDYATSEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEI-PASKLKREIADILKREGFIRDVE FVE----D---S----KQGIIRVFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKSNEVPRVLNGLGIAII STSQGVLTDKEARAKQAGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVVVETYKKDPIYG KRVKYSKKFKAHDEN--NQAKIGDIVKIMETRPLSATKRFRLVEVVEEA------------------------------- -MARSL-KKGPFVDG-HLMTKIEKLNE---TDKKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVFISE-DMVGH KLGEFAPTRTYKGHA------S--DDK----KTR------R- >FIRM_Bacillus_anthracis_A0248 Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKNLEVGMEIMSGA-E-AD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--D-V-FATGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALVSKFNYKSVMQVPKIEKIVINTGVG-DAVSNSKTLDNAVEELTQITGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------AKTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -AED--N-TVTVKGPKGELTRTF--NA-D--MLIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TEGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMT--P-EAGLEVEVP--A-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------ILA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSV-R---EHR--GKM---RGRA-KGGTEIAFG----------EFGLQAQ--AASWITNRQIE AARRAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVFRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL-------ALNGT-SNIEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MQ-AKAVARTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSE-MHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-ILDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--VI-RDWESRWFA------E-K D--YATLLHEDIKIREYI--NVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIAELLKREGFIRDVE YIE----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSADKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLVEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMSKIAKLNE---TEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHD------A--DDK----KTR------R- >FIRM_Bacillus_anthracis_Ames_Ancestor Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKNLEVGMEIMSGA-E-AD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--D-V-FATGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALVSKFNYKSVMQVPKIEKIVINTGVG-DAVSNSKTLDNAVEELTQITGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------AKTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -A-E-DN-TVTVKGPKGELTRTF--NA-D--MLIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TEGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMTP-E-A-GLEVEVP--A-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------ILA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSV-R---EHR--GKM---RGRA-KGGTEIAFG----------EFGLQAQ--AASWITNRQIE AARRAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVFRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL---AL----NGT-SNIEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MQ-AKAVARTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSE-MHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-ILDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--VI-RDWESRWFA------E-K D--YATLLHEDIKIREYI--NVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIAELLKREGFIRDVE YIE----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSADKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLVEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMSKIAKLNE---TEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHD------A--DDK----KTR------R- >FIRM_Bacillus_cereus_AH187 Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKNLEVGMEIMSGA-E-AD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--D-V-FATGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALMSKFNYKSVMQVPKIEKIVINTGVG-DAVSNSKALDNAVEELTQIAGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------ANTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -A-E-DN-TVTVKGPKGELTRTF--NA-D--MLIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TEGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMTP-E-A-GLEVEVP--A-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------ILA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSV-R---EHR--GKM---RGRA-KGGTEVAFG----------EFGLQAQ--AASWITNRQIE AARRAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVFRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL---AL----NGT-SNIEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MQ-AKAVARTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINNLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSE-MHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-ILDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--VI-RDWESRWFA------E-K D--YATLLHEDIKIREYI--NVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIAELLKREGFIRDVE YIE----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLVEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMSKIAKLNE---TEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHD------A--DDK----KTR------R- >FIRM_Bacillus_cereus_ATCC_14579 Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKSLEVGMEVMSGP-E-AD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRASIGQVGNEQHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--D-V-FATGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALVSKFNYKSVMQVPKIEKIVINTGVG-DAVSNSKALDNAVEELTQITGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------AKTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -A-E-DN-TVTVKGPKGELTRTF--NA-D--MLIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TEGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMTP-E-A-GLEVEVP--A-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------VLA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSV-R---EHR--GKM---RGRA-KGGTEIAFG----------EFGLQAQ--AASWITNRQIE AARRAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVFRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL---AL----NGT-SNIEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F-------------------------------------------------------------SMQ-AKAVARTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINNLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSE-MHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-ILDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--VI-RDWESRWFA------E-K D--YATLLHEDIKIREYI--NVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIAELLKREGFIRDVE YIE----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLDEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMSKMEKLVA---SEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYITE-DMVGH KLGEFAPTRTYKGHL------A--DDK----KTR------R- >FIRM_Bacillus_clausii_KSM-K16 Concatenation of 2 sequences MAIKKYKPTSAGRRNMSVSDFAE-ITTD------------KP-EKSLLAPLHKKGGRNNQGRLTVRH-QGGGHKRQ---- YRVIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYILAPKGLTVGTVIVSGP-D-AD-IKTGNALPLA NIPVGTVIHNIELRPGKGGQLVRSAGTEAQLLGK--EGDYALVRLNSGETRYILSTCRATIGQVGNVEHELINIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGRPSPMSP---WGKPTLGYKTR-KKNKHSD-K-YIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------VIPVTVIEAEPNI VLQKK----TVE----S--DGY--EAIQIGF-------AD---PNK----------PATGHAK----------------- ---AE-TAPKRFIKEIRG--------VNLDEV-----EV---GQ-AINV--T-T-FAAGDLVDVTGTSKGKGFQGAIKRH NQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKALPGRMGGEQITMQNLEIVRVDEERN---------------- ----------LLLVKGN-VPGAKKSYVTVQ-MPKVSLFN-QTGSQV-GEIELADNVF----GV-EP-NESVLHDAVVMQQ ASLRQGTHKTKGRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- VGGGVVFGPT-P-RSYSYKLPKKVRRLAIKSALSSKVKDS----------------E-LVVLDDL----KLE-A------ --IKTKLVV--TADYN--E---NVALSARNLPGIT-F---------------LTADGVNVLDLLKHDK----LVITKDAV EKVENRLKEKYQNEI----VSSLTEKFNYPSVMAVPKIEKIVVNMGIG-DAVQNAKVLDKAVEELQAITGQKPVITKAKK SIAGFKLREGMPIGAKVTLRGERMYDFLDKLVSVSLPRVRDFRGVSK-KAFDGRGNYTLGVREQLIFPEID-----YDKV DKVRGMDIVIVTT-----------------------AKTDEEARELLTQVGMPFMSRVG-K--KPVIIPDGVTVT-F--- -D-G--N-LCTVKGPKGELSREL--HP-D--IKITVEG-NE--ITF---ER-P--SDHKEHR-ALHGTMRALVNNMVEGV TKGFERALELNGVGY--RASKSG-NK--LVLN--VGYSHPVEITP-E-E-GLEIEVP--S-NTKVVVKG-INKERVGALA SNIRAVR------LPEPY---KGKGIRYEGEYVRRKEGK----------MIQQESRLKVADNSGAREVLCIKVLG-SGRK I--ANIGDVIVCSVKEATPG-G-------VVKKGDVVKAVIVRSKSGVRRNDGSYIKFDENAAVIVR-DDKS-PRGTRIF GPVARELR-DNQFMKIVSLAPEVLMK-L--HELQPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQKARSGGG-V--- -RPGF-E-GGQNPLYRRLPK-RG--FTNVNLDVLVTPELLIET-KTVKIK---------VLG--NGN-L-D-K-N-LTV- KAHKFSASAVKAIEAAGGKT-R---EHR--GKM---RGRA-KGGTEVHFG----------EFGLQAL--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--SG-- VSEEVAREALRLASHKLPIKCKF-VKNAGRKKRHAHVRRTL---SGTPQRPRLNVFRSSKHIYAQLIDD---V--NGVTL AQASTL-DKEL---GL----ENG-GNKEAARKVGELVGKR--AVDAG-FESVVFDRGGYLYH--GRIAELADGAREAGLK F-------------------------------------------------------------MEQ-AKAVAKQVRIAPRK VRLVIDLIRGKQVGEAIAILKHT---------------------------------PKAASPVVEKLLNSAIAN----A- EHNY-EMEPNNLVISEAYVNEGVTLKRFRPRAQGRASRINKRTSHITLVVTE-MHVKKGDKVVVITGK------DK-GKQ GTVLEAYPKKS--RVL--VEGVNMVKKHAK----PS--QD-NPQ-GGILNQEAPIHSSNVM-LVDPKT-------GE--R --TRVGYKE----E--------NGKVR---VAKKSG---EII--MGQKVNPVGLRVG--VI-RDWDSKWYA------GKK D--YADLLHEDIAIREHV--EGRLK-----DASVSKVEIERAA-N-RVNITISTAKPGMVIGKGGSEVEALRKSLNELVH INISEIKQ---ADLDAKLVAENIARQLENRISFRRAMKQAIQRTMRA-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYGTAEADTTYGKIGVKIWVYMVMTDPIADMLTRIRNANLVRHEKLEL-PASMLKKEIADILKREGFIRDYE FIE----D---N----KQGVIRIFLKYG---PSN-------E---RVITGLKRISKPGLRVYAKSTELPRVLGGLGIALV STSKGVLTDKEARQQQVGGEVLAYVWMAKQKIRIRLKAYDHRVLDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIINPTPQTVDALMRLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVLVETYKKDRLYG KRVKYSKKFKAHDEQ--NTAKVGDIVRIMETRPLSKDKRFRLVEIVEEA------------------------------- -MGRSL-KKGPFVDG-HLMKKVEALNA---TNDKK----VVKTWSRRSTIFPDFIGHTFAVYDGRKHVPVYVSE-DMVGH KLGEFAPTRTYKGHA------A---DK----KTR------R- >FIRM_Bacillus_halodurans_C-125 Concatenation of 2 sequences MAIKKYKPTSAGRRGMSTLDFAE-ITTD------------KP-EKSLLAPLHKKGGRNNQGKMTVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKGLKVGMTIESGP-E-AD-IKVGNALPLK NIPVGTVIHNIELKPGKGGQLVRSAGAEAQLLGK--EGDYVLVRLNSGETRYILATCRATIGQVGNLEHELVNIGKAGRS -RWL-----GKR-P-TVRGSAMNPNDHPHGGGEGRA-P--IGRKSPMSP---WGKPTLGYKTR-KKNKASD-K-YIVRRR --------------------------------MSK---G-ILGKKVGMTQVFA-ENGD---------VIPVTVIEAAPNV VLQKK----TVD----S--DGY--EAVQLGF-------DD--QANK----------PEKGHAK----------------- ---AE-TAPKRFIKEIRG--------VNLDEF-----EV---GQ-EIKV--D-A-FAEGDIVDVTGTSKGKGFAGAIKRH NQAR-GPMSHGS-RYHRR-PGSMG-P-VDPN-RVFKGKALPGRMGGEQVTVQNLEIIKVDAERN---------------- ----------LLLVKGN-VPGAKKSYVTVR-MPKVALYN-QAGSQV-GDIELSDAVF----GI-EP-NENVLHDAVVMQQ ASLRQGTHKTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- VGGGTVFGPT-P-RSYSYKLPKKVRRLAIKSALSSKVKAE----------------E-IVVLESL----ALE-A------ --PKTKLVV--TADYN--D---NVALSARNIPGVT-F---------------VTAEGVNVLDVIKHDK----LIITKDAV EKVENRLKEKYQKEI----VPSLTEKFNYSSVMAVPKLEKIVVNMGVG-DAVQNAKALDKAVEELTEITGQKPIITKAKK SIAGFKLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFRGISK-KAFDGRGNYTLGVKEQLIFPEID-----YDKV DKVRGMDVVIVTT-----------------------ASTDEEARELLSQMGMPFMSRIG-N--KPVEIPSGVTVT-V--- -N-G--A-DVTVKGPKGELKRTF--NP-E--IVVKVED-NT--VVV---ER-P--SDKKEHR-ALHGTTRSLISNMVEGV SKGFEKSLELVGVGY--RAQKSG-QK--LVLN--VGYSHPVEIV--P-EKGIEIEVP--S-NTKVTVKG-IDKERVGAVA SNIRSVR------LPEPY---KGKGIRYEGEYVRRKEGK----------MIQQESRLKVADNSGARELLCIKVLG-SGRK T--ANIGDVIVCSVKQATPG-G-------VVKKGDVVKAVIVRSKSGVRRNDGSYIKFDENAAVIVR-DDKS-PRGTRIF GPVARELR-DNQFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQNPLYRRLPK-RG--FTNVNLEKLVSPELLLET-GVVSIK---------ILG--NGK-L-E-K-K-LTV- KANKFSASAVEAIEAAGGKT-R---EHR--GKM---RGRA-KGGTEVHFG----------EYGLQAL--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVMFEI--SG-- VSEEVAREALRLASHKLPVKCKF-VKNVARKKRHAHVRRTI---TGTPERPRLNVFRSSKHIYAQLIDD---V--NGVTV AAASSL-DKEL---KL----ENG-GNVEAAKKVGELVAKR--ALEKG-YKTIVFDRGGYVYH--GRVASLADAAREAGLQ F--------------------------------------------------------------MQ-AKAVAKQVRIAPRK ARLVIDLIRGKQVGEAIAILKHT---------------------------------PKAASPIIEKVLNSAIAN----A- EHNY-EMEPNNLVISEAFVDEGVTLKRFRPRAMGRASRINKRTSHITIVVTE-MHVKKGDTVKVISGK------DK-GKQ GVILEAYPKKD--RVL--VEGVNIVKKHAK----PS--QE-NPQ-GGILNMEAPIHVSNVL-PIDPKT-------GE--P --TRVGYKV----E--------NGKVR---IAKKSG---EVL--MGQKVNPVGLRVG--VI-RDWESKWYA-------EK D--YADLLHEDIKIREYI--ENRLK-----DASVSKIEIERAA-N-RVNITISTAKPGMVIGKGGSEVEALRKALNELVH INIFEVKQ---ADLDAKLVAENIARQLENRISFRRAMKQAIQRTMRA-GAQGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYGTAEADTTYGKLGVKIWIYMVMTDPISDMLTRIRNANTVRHEKLEL-PASKIKKEIAEILKREGFIRDYE YIE----D---S----KQGVIRIFLKYG---SSN-------E---RVITGLKRISKPGLRVYAKAGELPRVLGGLGIAIV STSKGVMTDKEARQQQVGGEVLAYVWMAKQKIRIRLKAYDHRVLDQSAEKIVETAKRSGANVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKKDRLYG KRVKYSKKFKAHDEN--NSAKIGDIVRIQETRPLSKDKHFRLVEIVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKIETLNE---SNDKK----VVKTWSRRSTIFPEFVGHTIAVYDGRKHVPVYISE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Bacillus_licheniformis_ATCC_14580_(Goettingen) Concatenation of 2 sequences MAIKKYKPTSNGRRGMTSSDFAE-ITTD------------QP-EKSLLAPLHKKGGRNNQGKLTVRH-QGGGHKRQ---- YRIIDFK-R--DK-DGIPGRVATVEYDPNRSANIALINYV-DGEKRYILAPKGLQVGTEIMSGP-E-AD-IKVGNALPLI NIPVGTVVHNIELKPGKGGQLVRSAGTSAQVLGK--EGKYVLVRLNSGEVRMILSACRATIGQVGNEQHELINIGKAGRS -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRKSPMSP---WGKPTLGFKTR-KKKNKSD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVIEAAPNV VLQKK----TSE----N--DGY--EAIQIGF-------DD--KANK----------PEKGHVK----------------- ---AE-TAPKRFVKELRG--------VDMDAY-----EV---GQ-EVKV--D-I-FSNGEIVDVTGTSKGKGFQGAIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VDPN-RVFKGKLLPGRMGGEQITVQNLEIVKVDAERN---------------- ----------LLLVKGN-VPGAKKSLVTVK-MPKVALYN-QNGSTA-GDIELNDSVF----GI-EP-NESVVFDAILMQR ASLRQGTHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYAYKLPKKVRRLAIKSALSSKVNDN----------------N-LIVLEDL----NLD-A------ --VKTKLIV--TADAN--E---TVELSARNLPGVT-V---------------VEANGINVLDVVGHEK----LVMTKAAV EKVENRLKEKYNKEI----TPALMKKFEYKSVMQVPKIEKIVINMGVG-DAVQNAKAIDSAVEELTFIAGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLISVSLPRVRDFRGISK-KSFDGRGNYTLGIKEQLIFPEID-----YDKV TKVRGMDIVIVTT-----------------------ANTDEEARELLTQLGMPFMSRVG-K--KLLEIPSGVTVT-L--- -N-D--N-TVTVKGPKGELTRTF--HP-D--MKIKIED-NV--LTV---ER-P--SDNKEHR-ALHGTTRSIIGNMVEGV SKGFERGLELVGVGY--RASKSG-NK--LVLN--VGYSHPVEIVP-E-N-GIEIEVP--S-QTKVVVKG-TDKERVGATA ANIRAVR------SPEPY---KGKGIRYEGEMVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKQATPG-G-------VVKKGDVVRAVVVRSKSGARRNDGSYIKFDENACVIIR-DDKS-PRGTRIF GPVARELR-DNNFMKIVSLAPEVLMK-L--HELKPAEGS-RKTRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQMPLFQRLPK-RG--FTNVNLDKLVTPELLLET-GVISVK---------ILG--DGK-L-E-K-K-LTV- KANKFSASAKQAIEAAGGTA-R---EHR--GKM---RGRA-KGGTEVHFG----------EYGIQAQ--ESSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVLFEI--SG-- VSEEVAREALRLASHKLPIKTKF-VKNAARLKRHARVRAKL---SGTPERPRLNVFRSNKHIYAQVIDD---V--NGVTL VSASTL-DKDF---NA----ENG-SDTAAAAKVGELVAKR--ASEKG-ITNVVFDRGGYLYH--GRVKALADAAREAGLE F-------------------------------------------------------------MQQ-AKAVARTVRIAPRK ARLVMDLIRGKQVGEAVSILNHT---------------------------------PKAASPIIEKVLKSAIAN----A- EHNY-EMDANNLVVTQAYVNEGPTLKRFRPRAMGRASQINKRTSHITIVVSE-MHVKKGDKVMVISGK------DK-GKQ GVILAAFPKKD--RVI--VEGVNMVKKHSK----PT--QA-NPQ-GGILNQEAPIHVSNVM-PLDPKT-------GE--V --TRVGYKV----E--------NGKVR---IAKKSG---QVL--MGQKVNPVGLRIG--VI-RDWESKWYA------G-K D--YADFLHEDLKIREFI--NQRLS-----DASVSKVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKALNSLVH INILEIKR---ADLDAQLVADNIARQLENRISFRRAQKQQIQRTMRA-GAQGIKTMVSGRLGGADIARSEYYSEGTVPL- -HTLRADIDYATSEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEI-PASKLKREIAEILKREGFIRDVE FIE----D---N----KQGIIRVFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKSNEVPRVLNGLGIAIL STSQGVLTDKEARAKQAGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVVVETYKKHSLYG KRVKYSKKFKAHDEN--NQAKIGDIVKIMETRPLSATKRFRLVEVVEEA------------------------------- -MARSL-KKGPFVDD-HLMTKIEKLNE---ADKKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYISE-DMVGH KLGEFAPTRTYKGHA------S--DDK----KTR------R- >FIRM_Bacillus_pumilus_SAFR-032 Concatenation of 2 sequences MAIKKYKPTSNGRRGMTTSDFAE-ITTD------------KP-EKSLLAPLHRKGGRNNQGRLTVRH-QGGGHKRQ---- YRIIDFK-R--DK-DGIPGRVATIEYDPNRSANIALVNYA-DGEKRYILAPKGIQVGTEVTSGP-E-AD-IKPGNALPLI NIPVGTVVHNIELKPGKGGQLVRSAGTSAQVLGK--EGKYVLVRLNSGEVRMILSACRATIGQVGNEQHELINIGKAGRS -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRKSPMSP---WGKPTLGFKTR-KKTNKSD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVVEAAANV VLQKK----TTD----T--DGY--EAIQIGF-------DD--KSNK----------PEKGHVK----------------- ---AE-TAPKRFVKELRG--------AELDAY-----EV---GQ-EVKV--D-I-FANGDIVDVTGTSKGKGFQGAIKRH GQSR-GPMTHGS-RYHRR-PGSMGP--VDPN-RVFKGKLLPGRMGGEQITVQNLEIVKVDAERN---------------- ----------LLLIKGN-VPGAKKSLVTVK-MPKVALFN-QNGSTN-GEIELNASVF----GI-EP-NESVVFDAILMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYSYKLPKKVRRLAIKSVLSSKVIDN----------------N-IIVLEDL----TLD-A------ --VKTKLIV--TADAN--E---TVALSARNIPGVT-V---------------VEANGINVLDVVNHEK----LLITKAAV EKVENRLKEKYVKEI----TPALVSKFEYKSVMQVPKIEKIVINMGVG-DAVQNAKAIDTAVEELTFIAGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLISVSLPRVRDFRGISK-KSFDGRGNYTLGIKEQLIFPEID-----YDKV TKVRGMDIVIVTT-----------------------ANTDEEARELLTQVGMPFMSRIG-K--KLIEIPSGVTVT-N--- -N-D--N-TVTVKGPKGELTRTF--HP-D--MEIKIED-SV--LTV---SR-P--SDHKEHR-ALHGTTRSLIANMVEGV SKGFERGLELIGVGY--RAAKSG-NK--LVLN--VGYSHPVEIVP-E-A-GVEVEVP--S-QTKVVIKG-IDKERVGALA SNIRAVR------SPEPY---KGKGIRYEGEFVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRNDGSYISFDENACVIIR-DDKS-PRGTRIF GPVARELR-DNNYMKIVSLAPEVLMK-L--HELKPSEGS-RKERNRVG-RGIGSGN-GKTSGKGHKGQNARSGGG-V--- -RPGF-E-GGQMPLFQRLPK-RG--FTNINLDRLVTPELLLET-GAISVK---------ILG--NGK-L-E-K-K-LTV- KANKFSASAKEAIEAAGGTA-R---EHR--GKM---RGRA-KGGTEVHFG----------EYGIQAL--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVLFEI--SG-- VSEEVAREALRLASHKLPIKTKF-VKNATRLKRHARVRAKL---SGTAERPRLNVFRSNKNIYAQVIDD---V--NGVTL VSASTL-DKDL-KI------ENS-SDAAAATKVGELVAKR--AVEKG-ISNVVFDRGGYLYH--GRVKALAEAAREAGLK F--------------------------------------------------------------MQ-AKAVARTVRIAPRK ARLVMDLIRGKQVGEAVSILNLT---------------------------------PKAASPIIEKVLKSAIAN----A- EHNY-ELDANSLVITQAFVDEGPTLKRFRPRAMGRASAINKRTSHITIVVSE-MHVKKGDKVVVISGK------DK-GKQ GVILAAFPKND--RVL--VEGINLVKKHSK----PT--QA-NPQ-GGISEQEAPIHVSNVM-PLDPKT-------GE--V --TRVGYKV----E--------DGKVR---VAKKSG---QVL--MGQKVNPVGLRIG--VI-RDWESKWFA------G-K D--YADFLHEDLKIREFI--SKRLS-----DASVSKVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKALNSLVH INILEIKR---ADLDAQLVAENIARQLENRISFRRAQKQTIQRTMRA-GAQGIKTMVSGRLGGADIARSEYYSEGTVPL- -HTLRADIDYATAEADTTYGKLGVKVWIYMVMTDPIADLLTRIRNANMVRHEKLEV-PASKIKREIAEILKREGFIRDVE YVE----D---S----KQGIIRMFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKSNEVPRVLNGLGIAII STSQGVLSDKEARAKQAGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVVVETYKKHSLYG KRVRYSKKLKAHDEN--NQAKIGDIVKVMETRPLSATKRFRLVEVVEEA------------------------------- -MARSL-KKGPFVDD-HLMAKVEKLNE---TDKKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVFISE-DMVGH KLGEFAPSRTYKGHA------S--DDK----KTR------R- >FIRM_Bacillus_subtilis_168 Concatenation of 2 sequences MAIKKYKPSSNGRRGMTTSDFAE-ITTD------------KP-EKSLLAPLHKKGGRNNQGKLTVRH-QGGGHKRQ---- YRVIDFK-R--DK-DGIPGRVATVEYDPNRSANIALINYA-DGEKRYILAPKGIQVGTEIMSGP-E-AD-IKVGNALPLI NIPVGTVVHNIELKPGKGGQLVRSAGTSAQVLGK--EGKYVLVRLNSGEVRMILSACRASIGQVGNEQHELINIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRKSPMSP---WGKPTLEFKTR-KQKNKSD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVIEAAPNV VLQKK----TAE----N--DGY--EAIQLGF-------DD--KSNK----------PEKGHVK----------------- ---AE-TAPKRFVKELRG--------VEMDAY-----EV---GQ-EVKV--E-I-FSAGEIVDVTGVSKGKGFQGAIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VDPN-RVFKGKLLPGRMGGEQITVQNLEIVKVDAERN---------------- ----------LLLIKGN-VPGAKKSLITVK-MPKVALYN-QNGSTA-GDIELNASVF----GI-EP-NESVVFDAILMQR ASLRQGTHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYSYKLPKKVRRLAIKSVLSSKVIDN----------------N-IIVLEDL----TLD-T------ --AKTKLIV--TADAN--E---AVALSARNIPGVT-V---------------VEANGINVLDVVNHEK----LLITKAAV EKVENRLKEKYNKEI----APALMTKFNYDSVMQVPKIEKIVINMGVG-DAVQNAKAIDSAVEELTFIAGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLISVSLPRVRDFRGVSK-KSFDGRGNYTLGIKEQLIFPEID-----YDKV TKVRGMDIVIVTT-----------------------ANTDEEARELLTQVGMPFMSRVG-K--KLLEIPSDVTVT-L--- -N-D--NNTVAVKGPKGELTRTF--HP-D--MEIKVED-NV--LTV---AR-P--SDQKEHR-ALHGTTRSLLGNMVEGV SKGFERGLELVGVGY--RASKSG-NK--LVLN--VGYSHPVEIVP-E-E-GIEIEVP--S-QTKVVVKG-TDKERVGAIA ANIRAVR------SPEPY---KGKGIRYEGEVVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRSDGSYISFDENACVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVIMK-L--HELKPSEGS-RKTRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQMPLFQRLPK-RG--FTNVNLDKLVTPELLLET-GVISVK---------ILG--NGK-L-E-K-K-LTV- KANKFSASAKEAVEAAGGTA-R---EHR--GKM---RGRA-KGGTEVHFG----------EFGIQAL--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVLFEI--SG-- VSEEVAREALRLASHKLPIKTKF-VKNAARLKRHARVRAKL---SGTAERPRLNVFRSYKHIYAQIIDD---V--NGVTL ASASTL-DKDL---NV----EST-GDTSAATKVGELVAKR--AAEKG-ISDVVFDRGGYLYH--GRVKALADAAREAGLK F--------------------------------------------------------------MQ-AKAVARTVRIAPRK ARLVMDLIRGKQVGEAVSILNLT---------------------------------PRAASPIIEKVLKSAIAN----A- EHNY-EMDANNLVISQAFVDEGPTLKRFRPRAMGRASQINKRTSHITIVVSE-MHVKKGDKVMVISGK------DK-GKQ GTILAAFPKKD--RVL--VEGVNMVKKHSK----PT--QA-NPQ-GGISNQEAPIHVSNVM-PLDPKT-------GE--V --TRVGYKV----E--------DGKVR---VAKKSG---QVL--MGQKVNPVGLRIG--VI-RDWESKWYA------G-K D--YADFLHEDLKIREYI--SKRLS-----DASVSKVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKALNSLVH INILEIKR---ADLDAQLVADNIARQLENRVSFRRAQKQQIQRTMRA-GAQGVKTMVSGRLGGADIARPEYYSEGTVPL- -HTLRADIDYATSEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEI-PASKLKREIPEILKREGFIRDVE FVE----D---S----KQGIIRVSLKYG---QNN-------E---RVITGLKRISKPGLRVYAKSNEVPRVLNGLGIAII STSQGVLTDKEARAKQAGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVVVETYKKHTLYG KRVKYSKKFKAHDEN--NQAKIGDIVKIMETRPLSATKRFRLVEVVEEA------------------------------- -MARSL-KKGPFVDG-HLMTKIEKLNE---TDKKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVFISE-DMVGH KLGEFAPTRTYKGHA------S--DDK----KTR------R- >FIRM_Bacillus_thuringiensis_Al_Hakam Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKNLEVGMEIMSGA-E-AD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--D-V-FATGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALVSKFNYKSVMQVPKIEKIVINTGVG-DAVSNSKALDNAVEELTQITGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------AKTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -A-E-DN-TVTVKGPKGELTRTF--NA-D--MLIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TEGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMTP-E-A-GLEVEVP--A-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------ILA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSVNR---EHR--GKM---RGRA-KGGTEIAFG----------EFGLQAQ--AASWITNRQIE AARRAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVFRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL---AL----NGT-SNIEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F-------------------------------------------------------------SMQ-AKAVARTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKMHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-ILDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--VI-RDWESRWFA------E-K D--YATLLHEDIKIREYI--NVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIAELLKREGFIRDVE YIE----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLVEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMSKIAKLNE---TEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHD------A--DDK----KTR------R- >FIRM_Bacillus_thuringiensis_sv_konkukian_97-27 Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKNLEVGMEIMSGA-E-AD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--D-V-FATGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALVSKFNYKSVMQVPKIEKIVINTGVG-DAVSNSKALDNAVEELTQITGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------AKTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -A-E-DN-TVTVKGPKGELTRTF--NA-D--MLIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TEGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMTP-E-A-GLEVEVP--A-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------ILA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSV-R---EHR--GKM---RGRA-KGGTEIAFG----------EFGLQAQ--AASWITNRQIE AARRAMTRYM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVFRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL---AL----NGT-SNIEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MQ-AKAVARTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSE-MHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-ILDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--VI-RDWESRWFA------E-K D--YATLLHEDIKIREYI--NVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIAELLKREGFIRDVE YIE----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLVEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMSKIAKLNE---TEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHD------A--DDK----KTR------R- >FIRM_Bacillus_weihenstephanensis_KBAB4 Concatenation of 2 sequences MGIKKYNPTTNGRRNMTTNDFAE-ITTD------------RP-EKSLLAPLSKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYV-DGEKRYILAPKTLEVGMEVMSGP-E-SD-IKIGNALPLI NIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGK--EGKYVLVRLTSGEVRLVLSACRASIGQVGNEQHELIKIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRS-P--IGRKSPMSP---WGKPTLGFKTR-KKNKASD-K-FIVRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGE---------LIPVTVIAANPNV VLQKK----TTE----T--DGY--NAIQLGF-------ED--KTNK----------PEQGHTK----------------- ---AS-TTPKRFIREIRD--------ADVDGL-----EV---GQ-EVKV--E-V-FAAGEIVDVTGISKGKGFQGVIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKGKKLAGRMGGDQVTIQNLEIVQVDTERN---------------- ----------LLLVKGN-VPGAKKSLVVVQ-MPKVTVYN-QTGSQV-GEIELAEAIF----GI-EP-NEAVLFEAVMMQR ASLRQGTHKVKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYKLPKKVRRLAIKSALATKVVEN----------------N-IVVLEDL----VLN-A------ --PKTKLIV--TADAN--E---SVELSARNIPGVT-V---------------ITADGVNVLDVLHHDK----LIMTKAAV EKVENRLKEKFQKEI----TPALMSKFNYKSVMEVPKIEKIVINTGVG-DAVSNSKALDNAVEELTQIAGQKPVVTRAKK SIAGFRLREGMPIGAKVTLRGQQMYEFFDKLVSVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------AKTDEEARELLTQFGMPFMSRIG-K--KILEIPAGVTIT-V--- -AED--N-TVTVKGPKGELTRTF--KT-D--MSIKIEE-NT--LTV---ER-P--SEQKEHR-ALHGTTRALIGNMVEGV TTGFARGLELVGVGY--RAQKQG-DK--LVLS--VGYSHPVEMT--P-EAGLEVEVP--V-PTKIVIKG-IDKQRVGEFA ANIRAVR------APEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK Y--AYIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGIGSGN-GKTAGRGHKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLSTLVTPELLLET-GVISVK---------ILA--SGA-V-E-K-K-LTV- KAHKFSSSAKEAIEAAGGSV-R---EHR--GKM---RGRA-KGGTEIAFG----------EFGLQAL--AASWITNRQIE AARRAMTRHM------KRGGKVWIKIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLAAHKLPVKCKF-VKNATRKKRHARVRAKL---TGTAERPRLNVYRSNQHIYAQVIDD---V--NGVTL VSASTL-DKDL-------ALNGT-SNTEAATKVGESVAKR--AVEKG-VKEVVFDRGGYLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MQ-AKAVVRTVRIAPRK VRLVVDLIRGKQVGEAIAILNHT---------------------------------PKTASPVVEKVLKSAIAN----A- EHNY-EMDINNLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSE-MHVKKGDKVQVITGK------DK-GKQ GVILVAFPKQN--RVI--VEGVNIVKKHSK----PS--QL-NPQ-GGIITKEAPIHVSNVM-VLDPKT-------GE--P --TRVGFKV----E--------DGKVR---IAKKSG---ELL--MGQKVNPIGLRVG--II-RDWESRWFA------E-K D--YATLLHEDIKIREYI--TVRLK-----DSAVAKVEIERAA-N-RVNVTIHTAKPGMVIGKGGTEVEALRKALNQLVH INILEVKR---ADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRA-GAKGIKTQVSGRLGGADIARAESYSEGTVPL- -HTLRADIDYAAVEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKKEIADLLKREGFIRDVE YIG----D---N----KQGILRIFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADEVPRVLNGLGIALV STSKGVMTDKDARQLQTGGEVVAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTIYTILRA VHKYKDSR-EQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKTHSLYG KRVKYSKKYKAHDEQ--NQAKLGDIVKIMETRPLSATKRFRLVEIVEEA------------------------------- -MARSL-KKGPFVDD-HLMNKMEKLVA---SEQKQ----VVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYITE-DMVGH KLGEFAPTRTYKGHL------A--DDK----KTR------R- >FIRM_Brevibacillus_brevis_NBRC_100599 Concatenation of 2 sequences MGIKKFKPTSPGRRQMTVSTFEE-ITTS------------TP-EKSLLAPLSKKAGRNNQGRITVRH-QGGGHKRK---- YRIIDFK-R--NK-DGIIGRVATIEYDPNRSANIALINYA-DGEKRYIIAPHNLKVGDQIVSGA-D-AD-IKIGNALPME KIPVGTTIHNIELKPGKGGQLVRAAGTSAQLLGR--DGEFVIVRLSSGETRRIHNVCRATIGQVGNLDHELLNIGKAGRS -RWL-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRKAPVTP---WGKPTLGLKTR-KKKNKSD-Q-YIIRRR --------------------------------MTK---G-ILGKKLGMTQVFG-PNGT---------ATAVTVIEVGSNV VLQKK----DVE----T--DGY--EAIQIGF-------ED--KANK----------PEKGHAK----------------- ---AN-TAPKRFIREIRG--------VNLADY-----EV---GQ-ELKA--D-I-FAEGEMVDVAGVSKGKGFQGAIKRH NQSR-GPMAHGS-RYHRG-PGSMGA--VAPN-RVFKGQTLPGQMGGDNVTIQNLEVIKVDTERN---------------- ----------LVLVKGS-VPGPKNSCVLVS-MPKVALYN-QTGSQV-GEIDLADSVF----GI-EP-NSAVLYDAIVMQQ ASQRQGTHDVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- KGGGVVFGPT-P-RKYGYKLNRKVRRLALKSALSTKVQNN----------------E-LLVLEAL----NFA-A------ --PKTKLIV--TSEYD--Q---NVALASRNIPGTK-I---------------VDAAGINVLDLVAHDK----VIVTREAV AKVETRLKEKYTSEI----VPSLMSKFNYTSIMQVPKVEKIIINMGVG-EAVANAKSLDTAIEDLQIIAGQKPVVTKAKK SIAGFKLREGMPIGAKVTLRGERMYHFLDKLMNVSLPRVRDFRGISS-KAFDGRGNYTLGLKEQLIFPEIE-----YDKI DKVRGMDIVVVTS-----------------------AKTDEEARELLTQMGMPFMSRVG-R--KPIVVPAGVTLT-L--- -N-G--T-ELTVKGPKGQLVRSF--HE-D--IKINIAE-NE--VIV---ER-P--SDNKLHR-SLHGTTRALVSNMVTGV SEGFTRTLELVGVGY--RAAKSG-NG--VTLS--LGFSHPVEVTP-E-E-GIEIDVP--N-QTTLVVKG-INKERVGQIA AEIRSLR------KPEPY---KGKGIKYSNEVVRRKEGK----------MIQTQTRLAVADNSGAKELMCIKVLG-SGRK T--ANIGDVIVCSVKSATPG-G-------VVKKGQVVKAVVVRTVSGVRRNDGSYIRFDENAAVVIK-DDQS-PRGTRIF GPVARELR-DKDFMKIISLAPEVIMK-L--HELQPAEGS-RHTRKRIG-RGIGSGT-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQNPLYRRLPK-RG--FTNVSLDALVTPELLKET-GVISVK---------VLA--NGE-L-T-V-K-LTV- KAHKFSGAAAEKIAQVGGTT-K---QHR--GKM---AGNA-KGGTTVAFG----------EYGLQAM--EPSWVTNRQIE AARIAMTRYI------KRGGKVWIKIFPDKPVTQKPLEVRMGSGK---------GSPEKWVAVVKP-GKIMFEL--AG-- VPEEVAREAMRLAMHKLPIKCKF-VKNKARKKRHLRIRKRV---IGTTIRPRLNVFRSSKHIYAQLIDD---A--TGVTL VSASSL-DKEL---GL----NNG-ANVEAATAVGTLIAKR--AQEKG-ATEVIFDRGGYIYH--GRIKALAEAAREAGLQ F--------------------------------------------------------------ME-AKAVARNIRIASRK VRLVVDLIRGKQVGEALAILKHT---------------------------------PKAASPVVEKLLKSAIAN----A- EHNY-EMDPNSLVVGKVFVDQGPTLKRFRPRAMGRASRIHKRTSHITVVLNE-MHVKKGDTVIVNAGK------DK-GKK GRVLAAYPKKE--RVL--VEGINLVKKHSR----PS--QA-NPQ-GGIVTQEAAIHVSNVS-LIDPKS-------GK--A --TRIGYKV---LD--------NGKVR---YAKKSG---EVL--MGQKVSPVGLRIG--VI-RDWESKWYA------D-K D--FATLLHEDLKIRKYV--KGRLK-----DAAVSTIEIERAA-N-RVNVTIHTAKPGMVIGKGGSEVETLRKTLTDLVH ININEIKR---PDLDATLVAENIARQLENRISFRRAQKQSITRTLRS-GAKGIKTLVSGRLGGADIARSEGYSEGTVPL- -HTLRADIDYGTAEAHTTYGRIGVKVWIYMVMTDPIADMLTRIRNANMVRHEKVEI-PASTIKKEIARILKEEGFIRDAE FVE----D---N----KQGIIRVFLKYG---AGN-------E---RVITGLKRISKPGLRVYAKNNEVPKVLGGLGCAII STSTGVMTDKQARQAHVGGEVLAYIWMAKQKIRIRLKAYDHKILDQSAEKIVDTAKRSGANVSGPIPLPTEKAVYTILRA VHKYKDSR-EQFEMRTHKRLIDILNPTPQTVDALMRLDLPSGVDIEIKLRRTVVGRVVSDKMDKTIVVLVETYKTHPLYG KRMKFSKKFKAHDEN--NTAKVGDIVEIMETRPLSKDKRFRLVRIVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKVDEQNE---KNEKR----VIKTWSRRSTIFPDFVGHTFAVYDGRKHVPVYVSE-DMVGH KLGEFAPTRTFKGHV------D--NDK----KSK------KR >FIRM_Caldicellulosiruptor_saccharolyticus_DSM_8903 Concatenation of 2 sequences MGIIVYKPTSPGRRNASVLNYKEIITKT------------EP-EKSLVFTEKKWAGRNNQGRITVRH-RGGGHKKK---- IRIVDFK-R--DK-DGIPAKVEAIEYDPNRTAFLALLCYA-DGERRYILAPEGLKVGDTVMSGP-D-AD-IKVGNALPLK YIPVGTMIHNIELYPGRGGQLVKSAGAVAQLMAK--EGKYALIRLPSGELRYVSQECRATIGQVGNLDHENVRIGKAGRK -RWM-----GIR-P-TVRGSAMNPVDHPHGGGEGKA-P--IGHPGPLTP---WGKPTLGYKTR-KKNKPSD-K-FIVKRR --------------------------------MTK---G-ILGKKIGMTQVFD-EAGK---------VVPVTVIEAGPCV VVQKK----TVE----K--DGY--AAIQVGF-------ED--ILNK----------PLRGHFK----------------- ---HG-VKPKRYLRELRL--------KDADKY-----EV---GQ-EIRV--D-I-FSPGERVDVTGISKAKGFQGVIKRH GQQR-GPMSHGS-MYHRR-VGSMGSN-TFPA-RTFPGKKMPGRMGGQRVTVLNLQVVKVDPERN---------------- ----------LLLVKGS-VPGNKNSLLIIR-MPKVPVYN-IEGQQI-GEIELNDSIF----NV-PI-NTHVLHQAVVAHL ANRRQGTFAAKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----TW---- RKGGVVFAKK-P-RDFSIDLPKKVRRLALKCALSSKVKEN----------------N-LIVLDKW----DMN-Q------ --YRTKLIV--IPEKN--E---YLQKSTKNIPEVK-T---------------LQVGNLNVFDILKYDK----FIILQDAV KKVEPRLKEKYYKEV----VPAMMQKFGYKNVMQVPRLGKIVVNIGLG-EGKDNPKALEAAVNDLMAITGQKPIVTRAKK SIANFKLRKGMPIGCMVTLRGDRMYEFLDKMINLALPRVRDFRGVSD-KSFDGRGNYSIGFKEQLVFPEID-----YDKV DKIRGLEVTIVTS-----------------------AKTDEEAKELLRLLGMPFMSRIG-K--KPIDIPSGVEVK-I--- -D-G--N-VITVKGPKGSLTKEI--HP-E--MIVKIEN-NQ--ILV---QR-P--SDERHHK-ALHGLTRTLIANMVAGV TKGYEKVLEIVGIGY--RAQKQG-KK--LILN--VGYSHPVEIEE-P-A-GITIEVP--D-QNRIVVKG-IDKQQVGNFA ANIRKVR------EPDPY---LGKGIKYADEVLRLKEGK----------MIQPQSRLKVADNTGAKEVMCIRVLG-SNRK F--ANIGDIIVCSVKDATPG-G-------VVKKGDVVKAVIVRTRKGIRREDGTYIRFDDNAAVLIR-EDKT-PRGTRIF GPVARELR-DKDFMKIVSLAPEVLMK-L--FELKPAPGA-KKRPKRVG-RGESSGH-GKTSTRGHKGQWARSGGG-V--- -RPGF-E-GGQMPLTRRIPK-RG--FKNVNVEKLITPELLLKE-GVISVK---------VLG--RGD-L-T-K-R-LIV- RVQKVSEGARKKIEAVGGKV-K---QQR--GRM---KGKA-TRGNFVAYG----------DFGIMAL--EPGWITSNQIE AARVAIARHI------KRGGKVWIKIFPDKPVTRKPAETRMGSGK---------GSPEYWVAVVKP-GRVMFEV--GG-- VDKEVAKEALRLAIHKLPIKCKI-VRNEKRLIRHKRIRKKV---FGTAERPRLCVYKSLKYIYAQIIDD---E--KGHTL VAASSL-EPEI-KSRL----TST-KSIEAAQYIGRVIAER--AKEKG-ITKVVFDRGGYPYH--GRVKALADAAREAGLE F-------------------------------------------------------------VKK-ATATLRYAMISPRK VRIVIDLIRNKPVQEALNILKFI---------------------------------PKRGARFVEKLLKSAIAN----A- ENNH-NMNVDKLYIAEIYANGGPMLKRIRPRAQGRAFLIRKRTSHITVVLKEKVHVKKGDTVVVISGK------YK-GKQ GKVLTVLPKDK--KVV--VEGVNIVKKHVR----PN--PK-MPQ-GGIITQEAPIWACKVM-LVCPKC-------NK--P --TRIGHRF---IQ--------EGKVR---TCKKCG---EII--MGQKVHPKGFRLG--II-KDWDSRWFA------NDK D--FEKYLLEDYKIRRHI--KEKLY-----NAGISRIEIERAA-K-RIKVIIHTAKPGIVIGRAGSGVEALRKELEKIIS LDIKEIKV---PELDAQLVAENIAAQLEKRVSFRKAMKQAMARALRS-GAKGIKTMVSGRLGGADIARTEWYKEGRIPL- -QTLRADIDYGFAEAHTTYGRIGVKTWIYMYVIDPIADMLTRIRNANNARHEVVDI-PASKMKKAIAQILLEEGFIKEYE IID----D---G----KNGIIRIKLKYG---PNK-------E---RAITGLKRISKPGRRVYAGKDELPKVLGGLGIAII STSKGIMTDKKARKEGVGGEVLCYIWSKAQRMRIKLKSFDYKLLDQSARKIVETAKSTGAEVSGPVPLPTDREVITIIRA PHKYKDSR-EQFEIKTHKRLIDIIKPTQKTVDALMRVELPAGVDIEIKLRKTRIGVVVSDKMDKTVVVAVETLVQHPLYK KTIKRTTKFKAHDEN--NECRVGDKVLIMETRPLSKEKRWRVVQILERA------------------------------- -MGRSL-KKGPYCDP-KLLKKIEKLNQ---NNEKK----VIKTWSRRSTILPQMVGHTIAVYDGRKHVPVYITE-EMVGH KLGEFAPTRTFKGHG------H-HTER----STA------LK >FIRM_Candidatus_Desulforudis_audaxviator_MP104C Concatenation of 2 sequences MATKKFKPTSPGRRFVTVSDFRE-VTVT------------EP-EKSLVEPLRKKAGRNFQGRVTVRH-RGGGHKRL---- YRVIDFK-R--NK-DGVPGKVATIEYDPNRSANIALVNYA-DGEKRYIVAPAGLKVGQEIMSGP-Q-AD-IKVGNALPLR NIPPGVLIHNIELYPGHGARVVRSAGGSAQLMAK--EGDYAHVRLPSGEVRLFPLDCRATIGQVGNVEHENIVIGKAGRA -RWL-----GIR-P-TVRGVVMNPVDHPHGGGEGRS-P--IGRP-PVTP---WGKPALGTRTR-NKKKASS-K-LIVKRR --------------------------------MWLMAKG-ILGRKLGMSRFFT-AEGV---------AVPVTLIEAGPCT VVQKK----TPD----T--DGY--SAVQLGF-------ME--QVNR----------PLKGHFR----------------- ---AG-VKPSRFLRELRV--------ADAADY-----EV---GQ-VLKA--D-L-FDVGEIVDVVGTSKGKGFAGGIKRH GFHR-GPMGHGS-KYHRR-PGALAA--KGPA-RVFKGRKLPGRLGGVRVTVQNLEIVKVDPERN---------------- ----------LLAVRGA-VPGIRGSLVVVK-MPTAAVFN-IEGQQV-GEIELSEAVF----GQ-PV-NDAVLHEVVVMQL ANRRQGTHDTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------HGT---IR-SP----IW---- RGGGIVFGPH-P-RDYSYRVPKKVKRLALKSALATKVDAG----------------R-ILVLDAL----ELP-G------ --PKTKLVV--TAERN--V---NVEKSARNLPGVK-S---------------LEARQLNVYDLLNHPH----LIITRDAV ARVESGLKQKYIEEV----IPAMMDKFKYRNVMEVPRLEKVVINIGMG-EAVQNAKAIDAAMQDLRTITGQQPVVTRAKK SVAAFKIREGMRIGLKVTLRGSRMYDFVDRLINVALPRVRDFRGVSP-KAFDGRGNYTLGLKEQLIFPEID-----YDKI DKVRGMDITFVTS-----------------------AKSDEEAREFLRLIGMPLMSRIG-R--MPIKIPPDVKIT-I--- -E-G--N-TVRVEGPKGRLEREI--PA-N--TKLVVEN-GR--AVI---EK-A--GEEKPGT-AMLGLTRTLVANMVDGV TKGFQRNLELTGVGY--RASLQG-RK--LVMT--LGYSHPVEYEP-P-A-DIEIEVP--A-VTRIIIRG-ADKEKVGRVA AKIRSFR------SPEPY---KGKGVRYEGEKIRLKAGK----------MIQVQTVLNVADNTGAKKLMCIRILS-SFRR Y--ASIGDIIVCSCKEAAPG-G-------VVKKGDVVKAVVVRTKKEIGRPDGSYIKFDENAAVVIK-DDKS-PRGTRIF GPVARELR-EKDFMKIVSLAPEVLMK-L--SELKPPAGA-RKKPTRKG-QGIATGQ-GKTAGRGHKGQKARSGGG-V--- -RRGF-E-GGQMPLTRRMPK-RG--FTNVNLEDLVTPEVLLEN-RMVRIK---------ILG--TGE-L-K-K-P-LTV- RAHAFSGAAREKIAAAGGKA-R---QHR--PDR---AGKA-KGGTKIQFG----------DLALQSL--DVAWISSRQIE AARIAMTRHV------KRGGKVWIRIFPDRPITAKPAETRMGSGK---------GSPEYWVAVVKP-GRIMFEI--AG-- VPEETAREALRLASHKLPCRTKI-VRKEQRERRRIRVRKKI---TGTRECPRLNVFRSARHIYAQLVDD---E--RGVTL CAASTL-LPEL-KERL----GDGGGKIGVARAVGEMIAEK--AKSLG-IERVVFDRAGYLYH--GRVKALAEGARAKGLE F--------------------------------------------------------------ME-AKAVARYIRLSPAK AREVVGLVRGKSVDEALAILRFT---------------------------------PQRAAGAVAKVIKSAAAN----A- EHNN-DMDRTRLVVAKVYVDQGPSLKRFRPRAYGRANVIKHRTSHITVIVSDKMNVRKGDKVVVITGK------DA-GKR GKIIEAIPDKN--KVI--VEGVNVVKRHSR----PT--RK-LPQ-GGIQEKEAPIDSSNVM-LLCARC-------HK--P --TRVGRRI---LD--------DGKVR---VCKKCG---EAL--MGQKVDPRGLRLG--IV-RDWDAKWYA------GKK D--FSNLLLEDVKIRDYI--KSKLL-----AAGISRIHIERTA-N-RVRIAIHTAKPGVVIGRGGTEVEVLRKELEKLIS INIVEIKT---PELDAQLVAENVAAQLQRRVAFRRAMKQAVGRAMKL-GAKGIRISVAGRLAGAEIARTEWYSEGKVPL- -HTLRADIDYGFSEAKTTYGKIGVKVWIY-MLTDPIADYLTRIRNANTAFHETTEV-PASGIKKALTEILKEEGFIRGFE VVD----D---G----KQGKIRIYLKYG---KNK-------E---RVITGLKRISKPGLRVYAGKEEVPRVLGGLGIAIL STSKGIMTDKEARKEGIGGEVICYIWMQRQKIRIRLKAFDHHMLDQSAQKIVETVRRTGADVAGPVPLPTEKEIYTILRS PHKDKDSR-EQFEIRTHKRLIDILEPTPKTVDALMRLDLPAGVDIEIKLRKVRTGRVVSDKMDKTVVVAVDTLVKHPLYG RTVRRTRKFMAHDED--NQCRIGDKVKIAETRPLSRHKRWRVAEVLERS------------------------------- -MGRSL-KKGPYCSP-KLLARIEEMNE---KDQKR----VVKTWSRRSTIFPQMIGHTIAVYDGRKHVPVYVTE-EMVGH KLGEFAPTRTYRGHG------H-HTER----STA------LK >FIRM_Carboxydothermus_hydrogenoformans_Z-2901 Concatenation of 2 sequences MAVKTYKPTSPGRRFVTVSSFEE-ITKT------------EP-EKSLIVPLKKHAGRNNQGRLTVRH-RGGGHKRM---- YRIIDFK-R--NK-DGIPAKVVAIEYDPNRTARIALLAYA-DGEKRYIIAPHGLKVGDVLMSGP-D-AD-IKVGNALPLA NIPVGTLVHNIELYPGKGGQLVRAAGTAAQLLGK--EGRYAILRLPSGEMRKVLLECRATIGQVGNLEHENITIGKAGRA -RWL-----GIR-P-TVRGVVMNPVDHPHGGGEGRS-P--IGRH-PVTP---WGKPTLGVKTR-KKNKASS-K-LIIKRR --------------------------------MPK---G-ILGRKVGMTQIFT-EDGR---------AIPVTVIEAGPCV VVQKK----TIA----N--DGY--NAIQLGF-------GE--IVNK----------PLKGHFR----------------- ---AN-VKPMRYLREIRV--------ENIDAY-----EV---GQ-EIKV--D-I-FTVGEKVDVTGISKGKGFAGGIKRH GFHR-GPMAHGS-KYHRR-PGSLGA--KGPA-RVFLGRKLPGRLGMERVTIQNLEVVKVDPERN---------------- ----------LLVIKGS-VPGIRGSLLIIK-MPKVPVYN-MEGAQV-GEIELKDEIF----GA-PV-NKAVLYEVSLMYL ANQRRGTHDTKTRGE--------VS-GGGRKPW---------RQKGTGRAR--------HGS---IR-SP----LW---- RKGGIVFGPH-P-RDYSYSVPKKVRRAALKSALSDKVNEN----------------N-LIVVDSL----TFA-A------ --PKTKLIV--TAGYD--E---IVEKSARNIPGVS-V---------------MTAPSLNALSLLNHDK----LIMTRDAV LKVEPRLKDKYQNDV----IPAMMEKFGYKNKMQVPKLEKIVINIGLG-EALQNPKAVDAAVADLMAITGQRPVLTKAKK SVAGFRVRQGATIGVKVTLRGDRMYEFMDKFVNIVLPRVRDFRGLSP-KSFDGRGNYSVGLREQLIFPEID-----YDKI DKVRGMEVTFVTT-----------------------AKTDEEARELLQLMGMPFMSRIG-R--KPIPVPQGVEVK-V--- -E-G--T-TVTVKGPKGSLTREF--HP-D--MKITFDG-SQ--ILV---ER-P--SDEKEHK-ALHGLTRTLINNMIVGV TNGYQKSLELVGVGY--RAAKQG-RK--LVLT--VGYSHPVEMDP-P-E-GIEIEVP--A-QNQIIVKG-IDKELVGNFA ATIRAVR------EPEPY---KGKGIKYTDEVIRRKAGK----------MIQVQTILNSADNTGAKKLMCIRVLG-SNRR Y--ASLGDIIVCSVKEATPD-A-------VVKKGEVVKAVVVRTKKEVRRPDGTYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-EKDFMKIISLAPEVLMR-L--HDLRPVPGS-RQKPTRKG-QGIGSGL-GKTAGRGQKGQKARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FHNINVDRLVTPELLLET-GIIKVK---------ILG--GGE-L-K-K-A-LTV- KAHAFSESAKEKITAAGGQA-R---PHR--PSL---KGKA-KGGTQLHFG----------EYGLQAV--EGAWITSQQIE AARVAISRYI------RRGGKIWINIFPDHPITRKPAETRMGSGK---------GAPEYWVAVVKP-GKIMFEL--AG-- VSEEVAREALRLASHKLPIKTKF-VRNLERKRRHLRVRKKI---HGTPERPRLNVYRSLKHIYAQIIDD---V--SGRTL VAASTL-DPEL-RGKI----GYG-GNIEAAKAVGRLIAER--AKAKG-IEKVVFDRGGYLYH--GRVKALAEAAREGGLQ F--------------------------------------------------------------ME-ARAVAKYIRISPRK ARQVIDLIRGKDVEEALAILRYT---------------------------------PKKASYFIEKVLRSAIAN----A- ENNH-DMSKENLYVAKAYVDQGPTLKRYNPRAQGRVDLWRVRTSHITIVVAEKLKVKKGDMVLVIAGK------DK-DKK GKIVQVLPKEN--RVV--VEGVNIVKRHTR----PN--PK-LPQ-GGIVEKEAPIHVSNVM-VICPSC-------GK--P --TRVGKKF---LA--------DGKIR---VCKKCG---ESL--MGQKVHPKGLRIG--II-KDWDAKWFA------DKK H--YQELLHEDLKIRKYI--KTKFY-----QAGISRIVIERAS-N-RVKVTIHTARPGMVIGKGGTEIEVLRKELEKMIN INIAEIKV---PEIDAQLVAENIAAQIEKRISYKRAMKQAVSRALKM-GAQGIKVACSGRLAGAEIARSEWYSEGKVPL- -TTLRADIDYGFAEALTTYGKIGVKVWIYMVMTDPIADFLTRIRNANMVYHEKVEV-PSSKVKRAIAEILKEEGFIKDYE YIE----D---G----KQGILRIFLKYG---PNK-------E---RVISGLKRISKPGLRVYAKKDELPRVLGGLGIAII STPKGIMTDKKARKEGLGGEVICYIWMNKQKIRIKLKAFEHTILDQSAAKIVETAKRTGASVSGPIPLPTERSLYTVLRS PHIDKDSR-EQFELKVHKRLIDIIDPTPKTIDALMRIDLPAGVDIEIKLQKIKIGRVVSDKMDKTVVVAVEELVSHPLYK KTIRRTKKFKAHDEH--NACRTGDIVKIAETRPLSKEKRWRVVEIIERG------------------------------- -MGRSL-KKGPYCDP-KLLKKIEELNA---KGEKR----VIKTWSRRSTIFPQMVGHTIAVYDGRKHVPVYITE-EMVGH KLGEFAPTRTFRGHG------D-HTER----STA------LK >FIRM_Clostridium_acetobutylicum_ATCC_824 Concatenation of 2 sequences MAVRGFKPTSPARRQMTVSTFEE-ITTD------------VP-EKSLLVSLNNKAGRNNNGKITVRH-RGGGNRNK---- YRLIDFK-R--NK-DGVPAKVTTIEYDPNRSAYIALVVYA-DGEKRYIIAPTKLSVGDTVVSGP-D-AD-IKIGNALPIK NIPVGTVIHNVELAAGKGAQLVRAAGSSAQLMAK--EGNYAQLRLPSGEMRYVRIECRATIGTVSNLTHDIVNIGKAGRK -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGKS-P--VGRPGPVTP---WGKPALGYKTR-KNKKYSD-K-LIVKRR --------------------------------MKK---G-ILGKKLGMTQIFN-EEGK---------VVPVTVIEAGPCV VIQKK----TSE----K--EGY--DAIQVGF-------GT--IVNK----------PLKGHFK----------------- ---GN-VELKRFVKEFRL--------EDTSSY-----EV---GA-EIKA--D-I-FAAGEKVDVSGVSKGKGFQGTIRRW GAHR-GPMSHGS-KFHRA-VGSMGGS-SDPS-RTFKSKKMPGHMGHVNTTVLNVEVAKVIPEKN---------------- ----------LILIKGG-VPGPNKSFVVIK-MPTVEVFN-KEGKKV-EDIELSEKVF----GA-KI-SESALHQVVVAQL ANKRQGTQSAKTRTE--------VS-GGGIKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IHGGVVFAPK-P-RDYRISIPKSMRRTAMLSALTSKVNDK----------------E-MIVLDEL----KID-A------ --PKTKLIV--VAESD--Q---NVYKSVRNIQGAA-V---------------IPANNLNVYDILKYDK----FIVTKEAV SKIEPRLKEKYEKEV----IPALMEKFQYKNIMEVPKLEKIVINMGVG-EAKENQKVLESAVADMQLISGQKPILTRAKK SVANFKIRENMPIGCKVTLRKNKMFEFADKLMNVALPRVRDFRGVSS-KSFDGRGNYALGIKEQLIFPEVE-----YDKI DKVRGMDVIFVTN-----------------------AKTDEEARELLRFLGMPFMSRVG-K--QPVEIPSGVTVT-V--- -T-P-DN-VVTVKGTKGQLEKAM--HK-D--MKIAVED-NK--VVV---TR-P--SDSKNHK-ALHGLTRALINNMVIGV TEGFSKTLQLVGVGY--KAQLKG-KS--LILN--LGYSHPIEVAS-I-E-GVTFEIP--D-ANTVVVKG-INKELVGSVA ADIRTFR------KPEPY---KGKGIKYSDEVIRRKEGK----------MIQAQTMLKVADNSGAKEIMCVRVLG-SKRK W--GNIGDIIVASVKSATPG-G-------VVKKGEVVKAVVVRSAKGLRRADGSYIKFDENAAVLIK-DDKQ-PRGTRIF GPVARELR-DKDFNKILSLAPEVLMK-L--HELKPAAGS-RKAPKRVG-RGTGSGL-GRNAGKGEKGQNARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNVNVDRLVTIDALIEK-GIIKVK---------ILG--NGE-L-K-K-K-LVV- KVNKYSKSAAEKIEAAGGKA-K---VQR--GRM---KGKA-TRGNFIAYG----------DFAIQAT--ECAWITSNQIE AARIAINRYV------KRGGKLWIKIFPDKPVTQKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEM--SD-- VTEEQAREAFRLASHKLPIKTKF-VKVQSRKRRHLRVRNKI---SGTPERPRLAVYRSEKNIYAQVIDD---V--NGTTL VSASTL-DKDF-SA------KAG-SNKEAAKLVGGIVAKK--ALDKG-IKQVVFDRGGYIYH--GRIKELAEAAREAGLE F--------------------------------------------------------------ME-AKAIAKYVRMSPMK VKIVLDLIRGKNVNEAFAILQYT---------------------------------PKDAAVVINKVLKSAVAN----A- ENNF-NLDGNRLYVSEAYAGQGPTLKRFQPHAQGRAFSIKKRSSHITVIVKEKIHVRKQDSVVVISGK------DR-GKI GEVLAVNPKKG--TVL--IKDVNVVVKHQK----AN--KE-NMQ-GGLIKKEAPINSAKVM-LYCTKC-------KT--A --TRISKKV---LD--------DGKVR---VCKKCG---ETF--MGQKVNPHGLRVG--VI-KEWNAKWYA------NSK N--FSSYLVQDNKIRKFV--KNKLS-----SAGVSRIEIERAA-K-RVKLNIHTAKPGMVIGKGGQGIEALKKDLVNFVL INIVEVKN---SDANAQLMAENIAQQLERRISFRRAMKQTIQRAMRT-GAKGVKTACAGRLAGAEIARTEQYHEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRIRNANVVRHGVVEL-PSSKIKKAMANILLQEGYLKDIE EYN----D---G----VVPMLRLSMKYG---KGK-------E---RIVTGLKRISKPGLRVYCRKEEIPKVLNGLGIAII STSKGIVTDKEARKLGLGGEVLCYVWMAKQKIRIRLKAFDHTILDQSAEKIVETAKTTGAKVAGPVPLPTEKDVVTILRS PHKYKDSR-EQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKLRKTRIGRVVSDKMDKTIVVAVETKVRHPLYG KTVNKTTKFKAHDEK--NEAKLNDRVQIMETRPLSKDKRWRLVEIVEKA------------------------------- -MSRSI-KKGPFVKE-SLLNKIVEMNK---AGDKK----VVKTWSRSSTIFPEMIGHTIAVHDGRKHVPVYISE-DMVGH KLGEFVLTRTFRGHG------N--TEK----TTS------VK >FIRM_Clostridium_beijerinckii_NCIMB_8052 Concatenation of 2 sequences MAVKKFNPITPARRQMTMPTFEE-ITSQ------------EP-EKSLLVALKSKAGRNAQGKITVRH-RGGGVKRK---- YRIIDFK-R--NK-DEIPAKVATIEYDPNRSAYIALAIYS-DGEKRYILAPAGLKVGDVIESGV-N-AD-IKPGNALPLK NIPVGTVIHNIELQRGKGGQLVRAAGGSAQLMAK--EGDYATLRLPSGEMRYVRIECRATIGTLSNATNDIVNIGKAGRK -RHM-----GWR-P-TVRGSVMNPNDHPHGGGEGKS-P--VGRPSPVTP---WGKPALGYKTR-KTKKYSD-K-FIIKDR --------------------------------MKK---A-IIGRKVGMTQIFD-EKGK---------VIPVTVVEAGPCV VVQKK----TLE----N--DGY--EAIQVGF-------DE--IANK----------PRKGHFK----------------- ---AG-ATLRRTLKEFRL--------DDISQY-----EV---GN-EIKA--D-V-FGAGDKVDVSAVSKGKGFQGSIKRW NQQR-GPMTHGS-KFHRA-PGSMGAS-SDPS-RTFKNKRMPGHMGSVNTTVLNLEVVKVIAEKN---------------- ----------LILIKGG-IPGPNKGTVVIK-MPTVGVFN-KEGNKV-ADMELNENVF----AA-EI-NEYALHQVVVALL ANKRQGTQSTKTRSE--------VR-GGGIKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- IKGGIVFAPK-P-RDYRVSVPKSMRKVAMKSALTSKVQDN----------------Q-MIVLDSL----NFE-A------ --PKTKLII--TAESN--E---VVYKSARNIQGIS-V---------------IPANNINVYDLLKYEK----LIITKDAV SKIETRLQEKYQKEV----VPAMIEKFGYKNIMEVPKLEKIVINMGVG-EAKENQKVLESAVNDLTLIAGQKPVLTRAKK SVANFKIRENMPLGCKVTLRKANMFEFADKLMSIALPRVRDFRGVSS-KAFDGRGNYSLGIKEQLIFPEIE-----YDKI DKVRGMDIIFVTT-----------------------ANTDEEARELLRFLGMPFMSRVG-R--LPIAIPADVTVT-V--- -T-P-DN-LVTVKGPKGELVKTM--HK-D--ISIAVEN-NE--VIV---TR-H--SEQKDHR-ALHGLTRALINNMVIGV KQGYQKTLDLVGVGY--RAQLQG-KK--LVMN--LGYSHPVEIEP-I-D-GITFETP--A-ATRVIVSG-IDKEKVGFAA ADIRKWR------VPEPY---KGKGIKYENEVIRRKEGK----------MIQQQTLLKVADNSGAKEIMCIRVLG-SKRK F--GNIGDVIVASVKSATPG-G-------VVKKGDVVKAVVVRSVKGVRRADGSYIKFDENAAVIIK-DDKQ-PRGTRIF GPVARELR-DKEFTKILSLAPEVLMK-L--HELKPAAGS-KKAPKRIG-RGTGSGL-GRNAGKGEKGQNARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNINLDRLVTPELLLER-RVVSVK---------ILG--NGT-L-E-K-S-LTV- KGCKFSKSAIEKIEAAGGKV-K---VQR--GRM---KGKA-TRGNFLAYG----------DYGIQAL--TCGWITSNQIE SARIAINRYI------KRGGKLWIKIFPDKPVTEKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEL--SG-- VPEETAREAMRLASHKLPVKTKF-VKKASREKRHLRVRKKV---FGTAERPRLSVFKSEKNIYAQVIDD---I--NGVTL VAASSL-EKDF--------AAKG-GNKEGAKLVGELVAKK--AIEKG-IDVVVFDRGGYIYH--GRIQELAQAAREAGLK F--------------------------------------------------------------ME-ARAIAKYIRMSPTK VGVILDLIRGKQVNEAFAILQYT---------------------------------PREAAVVINKVLKSAVAN----A- ENNL-ELNADNLYVSECFVGQGSTLKRFQPHAQGRAFKILKKTSNITVVVKEKIHVRKNDTVIVISGK------DK-GKT GEVLKAYPKTG--KVL--VQGVNIVKKHQK----AN--KG-QVE-SAIIEKEAAINSSKVM-LYCNKC-------KN--A --TRISNKV---LD--------DGKVR---VCKKCG---ETF--MGQKVNPHGLRVG--VI-KGWDAKWYA------NKK N--FADNLIEDNKIRKFV--KKELF-----SAGISKIEIERAA-K-RVKLNIYTAKPGVIIGKGGSGIEALKNKLTQFVL INIVEVKS---AEADAQLMAENIAAQLEKRISFRRAMKQTMQRAMKH-GIKGVKTACSGRLGGAEIARTEHYHEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRVRNANAVRHEVVEV-PSSNVKKEIANILLQEGYIKEIN EYN----D---G----VVPMLRLSLKYG---ANK-------E---RVITGIKRISKPGLRVYCKKDEVPKVLNGLGIAVV STSNGIMVDREARKNGLGGEVICYVWMSKQKIRIRLKAFDHTILDQSAEKIVETAKTSGAKVVGPVPLPTEKDVVTILRA VHKYKDSR-EQFEIRTHKRLIDIVNPSPKTVDALMRLNLPAGVDIEIKLRKKRIGRVVSDKMEKTIVVAVETKVRHPLYG KTVNRTTKFKVHDEN--NEAKINDRVSIMETRPLSKDKRWRLVEIVEKA------------------------------- -MSRST-KKAPFVHE-GLFKKIEEMNG---NGEKK----VVKTWSRSSTIFPQFIGHTIAVHDGRKHVPVYVSE-DMVGH KLGEFVLTRTYKGHD----------DK----TSK------R- >FIRM_Clostridium_botulinum_A_ATCC_3502 Concatenation of 2 sequences MAVKGFRPTTPTRREMTMCTFEE-ITTS------------TP-EKSLLVSLKKSGGRNANGKITVRH-IGGGAKRK---- YRIIDFK-R--NK-DNIPAKVVSIEYDPNRTAFIALVVYA-DGEKRYIIAPVGLKVGDTVVSGP-E-SD-IKVGNCLPIR NIPVGTVIHNIELAAGKGAQLVRSAGNSAQLMAK--EGDYSQVRLPSGEVRYIRVECRATIGVVSNQTSEIVNIGKAGRK -RHM-----GVR-P-TVRGSVMNPNDHPHGGGEGRS-P--IGHPSPRTP---WGKPALGYKTR-KNKKYSD-R-FIVKRR --------------------------------MKK---A-ILGKKLGMTQIFN-ENGK---------VIPVTVIEAGPCT VIQKK----TVE----K--DGY--EAIQVAF-------GD--IRNK----------PIKGHFK----------------- ---AG-VSVKRHIKEFKL--------EDSNSL-----EI---GQ-EIKA--D-V-FEAGERVDISGVSKGKGFQGTIRRW NAHR-GPMSHGS-KFHRA-VGSMGAS-SDPS-RTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKN---------------- ----------LILIKGG-VPGPNKGLVQIR-MPKVDLFN-QNGEKV-GDLQLADSVF----GV-EV-NTYAMHQVVKALL ANKRQGTQSAKTRAE--------VS-GGGIKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IHGGVVFAPK-P-RDYRMSIPKSMKKVAIKSALTSKVNEN----------------L-MVVVDEI----KLE-T------ --PKTKLII--TNNAE--E---NVYKSARNIEGVQ-I---------------IPVNNINVYDVLKYDK----VVITKDAV SKIEPRLQEKYEKEV----VSALMDKFGYKNIMEVPKLEKIVINMGVG-EAKENQKSLEAAVEDLAKITGQKPILTKAKK SVANFKIREDMPLGCKVTLRKQNMYEFADKLINVALPRVRDFSGVSS-KSFDGRGNYAIGIKEQLIFPEIE-----FDKI DKIRGMDIIFVTT-----------------------AKTDEEARELLRFLGMPFMSRVG-K--LPVAIPNGVTVT-V--- -T-P-DN-VVTVKGPKGELVKAM--SN-K--INIAVED-NS--VVV---TR-D--NDHKDVR-ALHGLTRALVNNMVTGV NEGYVKTLELIGVGY--RAQLQG-KK--LVLS--LGFSHPVEMEA-V-S-GVEFEVE--G-GTKVKVKG-IDKELVGAVA ADIRKWR------KPEPY---KGKGIKYENEVIRRKEGK----------MIQQQTRLKVADNSGAKEIMCIRVLG-SHRK W--GNIGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRSVKGLRRADGSYIKFDENAAVIIK-DDKN-PKGTRIF GPVARELR-DKEFNKILSLAPEVLMK-L--HELKAAEGA-NKASKRVG-RGTGSGL-GKTSGRGQNGQNSRSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FKNINLDRLVTPELLVEK-RVVKVK---------ILG--NGN-I-E-K-K-LTV- KAAKFSKSAIEKIEAAGGKV-K---VQR--GRM---KGKA-TRGNFIAYG----------DFGIQAT--ECGWITSNQIE AARIAINRYV------KRGGKVWIKIFPDKPVTEKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEI--SG-- VSETVAREAMRLASHKLPVKTKF-VRSQSRTRRHMRVRKKI---FGTAERPRLSVYRSEKHIYAQLIDD---V--EGKTL VAASSS-EKGF--------DGVG-SNKEGAKLVGKMVAEK--ALEKG-LKKVVFDRGGFIYH--GRIKELAEGAREAGLD F--------------------------------------------------------------ME-AKAIVRYVRMSPSK IGVVLDLVRGKDVNEAFAILKYT---------------------------------PKDAAEVIYKALKSAVAN----A- ENNL-NLDVNSLYISEVHVGQGPTLKRYQPHAQGRAFRIRKRTSHLTLVVKEKIHVRKKDTVVVISGK------DK-SKI GEVLSVLPKKG--KVI--VKDVNVVTKHQK----PN--RE-NMQ-GGIIHKEAPIFSSKVM-LYCDKC-------KS--A --TRISNKI---LE--------DGKVR---VCKKCG---ETF--MGQKVHPHGLRVG--VI-KEWDAKWYA------DKK N--FADNLVEDHKIRNFV--KKNSY-----AAGVSRIEIERAA-K-RIKLNIYTAKPGMIIGKGGQGIESLKNKLQKIIL INIVEVKR---PEADAQLIAENIAQQLEKRIAFRRAMKQSIQRAMRS-GVKGIKTACSGRLAGAEIARTEHYNEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMSDPIADLLTRIRNANVVRHEVVEV-PSSNIKKAIANIMLTEGYIRDLE EYR----D---G----SVDMLRITMKYG---QNK-------E---RIITGLKRISKPGLRVYCRKDETPKVLNGLGVAVV STSKGIVTDREARKLGVGGEVLCYIWMAKQKIRIRLKAFDHSLLDQSALKIVETAKTTGAKVAGPVPLPTEKDIVTILRA PHKYKDAR-EQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKLRKTRIGRVVSNKMDKTIVVAVETKVRHPLYG KIMNRTTKFKAHDEN--NAANINDKVLIMETRPLSKQKRWRLVEVVEKA------------------------------- -MSRSV-KKGPYIQE-VLLKRINEMNK---NGEKK----VLKTWSRSSTVFPQMIGHTIAVHDGRKHVPVYITE-DMVGH KLGEFVLTRTYRGHD-------DKSEK----SSR------LR >FIRM_Clostridium_botulinum_F_Langeland Concatenation of 2 sequences MAVKGFRPTTPTRREMTMCTFEE-ITTS------------TP-EKSLLVSLKKSGGRNANGKITVRH-IGGGAKRK---- YRIIDFK-R--NK-DNIPAKVVSIEYDPNRTAFIALVVYA-DGEKRYIIAPVGLKVGDTVVSGP-E-SD-IKVGNCLPIR NIPVGTVIHNIELAAGKGAQLVRSAGNSAQLMAK--EGDYSQVRLPSGEVRYIRVECRATIGVVSNQTSEIVNIGKAGRK -RHM-----GVR-P-TVRGSVMNPNDHPHGGGEGRS-P--IGHPSPRTP---WGKPALGYKTR-KNKKYSD-R-FIVKRR --------------------------------MKK---A-ILGKKLGMTQIFN-ENGK---------VIPVTVIEAGPCT VIQKK----TVE----K--DGY--EAIQVAF-------GD--IRNK----------PVKGHFK----------------- ---AG-VSVKRHIKEFKL--------EDSNSL-----EI---GQ-EIKA--D-V-FEAGERVDISGVSKGKGFQGTIRRW NAHR-GPMSHGS-KFHRA-VGSMGAS-SDPS-RTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKN---------------- ----------LILIKGG-VPGPNKGLVQIR-MPKVDLFN-QNGEKV-GDLQLADSVF----GV-EV-NTYAMHQVVKALL ANKRQGTQSAKTRAE--------VS-GGGIKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IHGGVVFAPK-P-RDYRMSIPKSMKKVAIKSALTSKVNEN----------------L-MVVVDEI----KLE-T------ --PKTKLII--TNNAE--E---NVYKSARNIEGVQ-I---------------IPVNNINVYDVLKYDK----VVITKDAV SKIEPRLQEKYEKEV----VSALMDKFGYKNIMEVPKLEKIVINMGVG-EAKENQKSLEAAVEDLAKITGQKPILTKAKK SVANFKIREDMPLGCKVTLRKQNMYEFADKLINVALPRVRDFSGVSS-KSFDGRGNYAIGIKEQLIFPEIE-----FDKI DKIRGMDIIFVTT-----------------------AKTDEEARELLRFLGMPFMSRVG-K--LPVAIPNGVTVT-V--- -T-P-DN-VVTVKGPKGELAKAM--SN-K--INIAVED-NS--VVV---TR-D--NDHKDVR-ALHGLTRALINNMVTGV NEGYVKTLELVGVGY--RAQLQG-KK--LVLS--LGFSHPVEMEA-V-S-GVEFEVE--G-GTKVKVKG-IDKELVGAVA ADIRKWR------KPEPY---KGKGIKYENEVIRRKEGK----------MIQQQTRLKVADNSGAKEIMCIRVLG-SHRK W--GNIGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRSVKGLRRADGSYIKFDENAAVIIK-DDKN-PKGTRIF GPVARELR-DKEFNKILSLAPEVLMK-L--HELKAAEGA-NKASKRVG-RGTGSGL-GKTSGKGQNGQNSRSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FKNINLDRLVTPELLVEK-RVVKVK---------ILG--NGN-I-E-K-K-LTV- KAAKFSKSAIEKIEAAGGKV-K---VQR--GRM---KGKA-TRGNFIAYG----------DFGIQAT--ECGWITSNQIE AARIAINRYV------KRGGKVWIKIFPDKPVTEKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEI--SG-- VSETVAREAMRLASHKLPVKTKF-VRSQSRTRRHMRVRKKI---FGTAERPRLSVYRSEKHIYAQLIDD---V--EGKTL VAASSS-EKGF--------DSVG-SNKEGAKLVGKMIAEK--ALEKG-LKKVVFDRGGFIYH--GRIKELAEGAREAGLD F--------------------------------------------------------------ME-AKAIVRYVRMSPSK IGVVLDLVRGKDVNEAFAILKYT---------------------------------PKDAAEVIYKALKSAVAN----A- ENNL-NLDVNSLYISEAHVGQGPTLKRYQPHAQGRAFRIRKRTSHLTLVVKEKIHVRKKDTVVVISGK------DK-GKI GEVLSVLPKKG--KVI--VKDVNVVTKHQK----PN--RE-NMQ-GGIIHKEAPIFSSKVM-LYCDKC-------KS--A --TRISNKI---LE--------DGKVR---VCKKCG---ETF--MGQKVHPHGLRVG--VI-KEWDAKWYA------DKK N--FADNLVEDHKIRNFV--KKNSY-----AAGVSRIEIERAA-K-RIKLNIYTAKPGMIIGKGGQGIESLKNKLQKIIL INIVEVKR---PEGDAQLIAENIAQQLEKRIAFRRAMKQSIQRAMKS-GVKGIKTACSGRLGGAEIARTEHYNEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMSDPIADLLTRIRNANVVRHEVVEV-PSSNIKKAIANIMLTEGYIRDLE EYR----D---G----SVDMLRITMKYG---QNK-------E---RIITGLKRISKPGLRVYCRKDETPKVLNGLGVAVV STSKGIVTDREARKLGVGGEVLCYIWMAKQKIRIRLKAFDHSLLDQSALKIVETAKTTGAKVAGPVPLPTEKDIVTILRA PHKYKDAR-EQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKLRKTRIGRVVSNKMDKTIVVAVETKVRHPLYG KIMNRTTKFKAHDEN--NAANINDKVLIMETRPLSKQKRWRLVEVVEKA------------------------------- -MSRSV-KKGPYIQE-VLLKRINEMNK---NGEKK----VLKTWSRSSTIFPQMIGHTIAVHDGRKHVPVYITE-DMVGH KLGEFVLTRTYRGHD-------DKSEK----SSR------LR >FIRM_Clostridium_cellulolyticum_H10 Concatenation of 2 sequences MAVKKYSPITPARRFMTSQDYSQ-LSKV------------EP-EKSLLQSKSKNGGRNSYGRITVRH-HGGGNRQK---- YRVIDFK-R--DK-DGIKAKVATIEYDPNRTANIALLNYA-DGEKRYILAPVGLKVGDFVESGE-S-SD-IRTGNALPLA NIPVGSMIHNIELKPGKGGQMVRAAGNAAQLMAK--EGEYAQIRLPSGEVRMVRINCRATLGQIGNIEHENVKIGKAGRK -RWM-----GVR-P-TVRGVVMNPVDHPHGGGEGKS-P--IGRPSPVTP---WGKPTLGYKTR-KKKKKSD-K-YIVKRR --------------------------------MKK---A-MLGKKIGMTQIFD-ENGL---------VIPVTVVEAGPLT VVQKK----TVE----T--DGY--DAIKVGY-------VK--VLSK----------PNLGQFK----------------- ---TK-LAPMKHLKEFRL--------EDISGF-----EV---GQ-EIKA--ENM-FQSGDKIDVSGVSKGKGFQGVTKRY GQRT-GPNTHGS-MYHRR-IGSMGSG-TNPG-RVFKGKKLPGHMGRETITVQNLEVVRVDSDRN---------------- ----------LILIKGA-IPGPKGGLLVIK-MPKVDLYN-MKGEVV-GDIQLSDNVF----GT-DV-NKDALHAVVVNQL ANRRQGTQSTKTKSE--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-SA----QW---- VKGGIVLGPK-P-RSYRYTLPKKVKRIAMKSALTSKVSGN----------------E-IFVLDAL----ALD-A------ --IKTKLLV--IDSKN--E---NIVKSARNIPGIK-T---------------AYVNTLNVFDILKYDK----FIITKDAV EKVETRLKDKYLNEA----APALIEKFKYSSRMQVPKLEKVVLNMGVG-EVKDNPKAMDSAVNDMTLITGQKPIVTKAKK SVAAFKLRQGMNIGCKVTLRGDRMYEFVDKLFNVAIPRVRDFRGLSS-NSFDGRGNYSMGIKDQLIFPEIE-----YDKV DKLRGMDIVFVTT-----------------------AKSDEEAKELLKLLGMPFMSRIG-K--LPITVPKGVTVK-L--- -E-G-DN-LLTVKGTKGTLSKKF-NKD----MIIKVEA-DQ--IVV---QR-P--SDLKIYK-SLHGLTRTLINNMVEGV TNGFQKTLEINGVGY--RAQKQG-KK--LVLT--LGYSHPVEMED-P-E-GIATEVP--A-PNKIIVKG-IDKQVVGEVA AKIREKR------LPEPY---KGKGIKYETEVIRRKEGK----------MIQVQSRMKVADNTGAKELMCIKVLG-SWRK Y--ANIGDVVVASVKNATPG-G-------VVKKGDVVKCVIVRSKKGVRRPDGSYIRFDENAAVIIK-DDKN-PRGTRIF GPVARELR-EKNFMKIVSLAPEVLMK-L--FELQPAPGS-KKLPNRKG-RGIGSGN-GKTGGRGHKGQNARAGGG-V--- -RPGF-E-GGQMPLYMRLPK-RG--FNNVNVSDLVTEELLKSS-GLAKVA---------ILG--NGE-L-T-K-K-LTV- QATKFTKTATEKIEAAGGKV-R---VHR--GRM---TGKA-TRGNFVSNG----------EFGIQAM--EPAWITSNQIE AARIAMTRFI------KRGGKVWIKIFPDKPVTKKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEI--AG-- VPEETAREALRLAMHKLPVKCKF-VRNKIRLRKHLRVRKKI---TGTAERPRMNVFRSLNNIYVQIIDD---T--TGNTL VSASTL-DAAL-KGKV----AKG-GNKEAAKEVGKLVASK--AIDKG-IKKVVFDRGGYIYH--GRIKELADAAREAGLD F-------------------------------------------------------------KDE-GRAVLKYARISSRK VKIVLDLIKNKGIDEAYGVLKFT---------------------------------PKAASEVLYKLLKSAEAN----A- VNNN-SLNYENLYIAEAFATQGPTLKRIQPRAQGRAFKIQKRTSHITLVVKEKVHVKKNDTVLVLSGK------DR-GKK GKVLSVNPSNN--QVL--VEGINISTKHKK----PR--GK-YQQ-GGIIHQESHIDSSNVM-LICDKC-------GK--P --TKVAKTI---LD--------NGKAR---TCKNCN---EII--MGQKVNPHGLRIG--II-KDWDTKWYA------NDK S--FSSYLVEDVKIRNFI--KKKLY-----ISGISRIEIDRAA-N-KVKINVNTAKPGLVIGKGGQGIEELRKEIEKMVL INITEIKV---PEMDAQLVAENIASQLEKRISFRRAMKQAMSRTMKL-GAKGIKTACSGRLGGAEIARTEHYHDGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWIYMQITDAIADMLTRIRNAGSAKHESVDI-PASNLKRSIANILLEEGYIKNFE EIS----D---G----KQGVLRVNLKYN----NK-------Q---NVITGIKRISKPGLRVYAGKDQLPKVLGGLGIAVI STSKGIMTDKKARVEGIGGEVLAFVWSNKQKIRIRLKAFDHQVLDQSAEKIVETAKRTGAKVSGPVPLPTEKEIITILRA PHKYKDSR-EQFEMRTHKRLIDVVLPTPKTVDALMRLDLPAGVDIEIKLRKTRVGKVVSNKMDKTIVVAIETSVKHPLYG KIVKRTYKLKAHDEE--NQCQIGDKVKVMETRPLSKEKRWRLVQIVEKA------------------------------- -MSRSV-KKGPYVLD-SLLKKIEEMNK---ANDKK----VIKTWSRASTIFPQMVGHTIAVHDGKKHVPVYITE-DMVGH KLGEFAPTRTYKGHS------G--NEK----STS------LR >FIRM_Clostridium_difficile_630 Concatenation of 2 sequences MAIKKFRPTSPALRQMTVLVSDE-ITCN------------QP-EKSLLVNLKKNAGRNVHGRITVRH-RGGGQKRK---- YRIIDFK-R--DK-DGIPAKVATIEYDPNRTANIALLNYA-DGEKRYILAPVGINVGDTILSGL-G-AD-IKPGNCLALK DMPVGTIIHNIELKPGKGAQLVRSAGVSAQLMAK--EGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRK -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGRS-P--IGRPSPVTP---WGKPALGYKTR-KKNKASN-K-LIVSRR ---------------------------------MK---G-ILGKKVGMTQIFT-DKGV---------VIPVTAVEAGPMV VTQIK----TVD----K--DGY--NAIQIGF-------ED--ALNK----------PKKGHL------------------ ---AAANVLKKHLKEFRV--------DSVEGY-----TV---GQ-EIKA--D-V-FEAGAKIDVTGISKGKGFQGPIKRH GQSR-GPETHGS-RYHRR-PGSMGAC-SYPG-RVFKNKKLAGHMGSVKVTVQNLEVVKVDADKN---------------- ----------LILVKGA-IPGAKGSVVTIKTMPKLNVLN-VSGQNV-GEIELSDSIF----GV-EV-NGHVLYEVVKNQL ANKRQGTQSAKTRAE--------VR-GGGRKPW---------KQKGTGRAR--------QGS---TR-SV----QW---- VGGGVAFAPK-P-RSYKYTLPKKVRRLAMKSALSSKVQNS----------------E-VIVLDAL----NMD-A------ --PKTKLVV--IADKN--D---NVIKSARNIEGVQ-T---------------ALVNTMNVYDILKYDS----FIITTDAV KKVESRLQEKYMKEV----APALMEKFGYKNVMEIPKLNKIVINMGIG-DARENPKGLEKGVEELEMISGQKPVITKARK SVANFKLREGMPIGTKVTLRADKMFYFMDKLVSVSLPRVRDFRGVNP-NAFDGRGNYALGVKEQLIFPEIE-----YDKI DKVRGMDIIFVTT-----------------------AKTDEEARELLKLLGMPFMSRIG-V--KPIIIPAGVEVT-I--- -A-E-GN-LVTVKGPKGTLTKQL--SA-E--LNIKKEE-NT--IMV---ER-P--TDNKKHR-SLHGLTRTLLDNMVVGV NTGFEKKLELKGVGY--RAQKQG-KK--LVMN--LGFSHPVEMED-P-E-GITVEAP--N-QTELIVKG-IDKQLVGNYA AKIRAWR------KPEPY---KGKGIKYVDEVIRRKEGK----------MIQQESRLRVADNSGAKELLCIRVLG-SKRR Y--GNIGDVIVATVKSATPG-G-------VVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIK-DDKT-PVGTRIF GPVARELR-DNEFMKIVSLAPEVLMK-L--HELKPAEGA-VRAKRRLG-RGTATGQ-GKTAGRGQKGQWSRSGGG-V--- -RVGF-E-GGQMPLARRLPK-RG--FNNVNVEVLITAELLKST-KTISIK---------ILG--EGN-L-E-K-A-LTV- KAAKFTASAQEKIEKAGGKA-R---VHR--GSM---AGQA-HKGNKVTYG----------EFGLVAL--EASWITSNQIE AARIAMTRYI------KRGGKVWIKIFPHKPVTRKPAETRMGAGK---------GSPEYWVAVVKP-GRVMFEL--AG-- VSEDKAREAMRLAAHKLPIKCKF-VKNANRLQRHKRVRRKI---SGTSQRPRLCVFRSANNIYAQIIDD---T--KRVTL VAASSL-EAEV-KSAV----NHT-GNKEAAKKVGELVAKK--AVEKG-ITEVVFDRGGYLYH--GRIQELAEGAREAGLK F--------------------------------------------------------------ME-AKATAKYVRVSPRK AGQICDLVRGKNVDEALAILKFT---------------------------------PRGAASIIAKVVKSAKAN----A- ENNH-EMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSHIEVVVKEMMRVKKGDTVVVIAGK------DK-GKK GSVLKVYPKTS--KVL--VEGVNVITKHQK----PS--AM-NQQ-GGIINKEAPIHISNVM-PFDPET-------GK--G --VRVRYEV----K--------DGKVR---VSAKSG---KEL--MGQKVNPHGLRVG--VI-KDWDSRWFA---T--DKK E--FGNLLLEDHNIRKFL--KKRLY-----SAGVAKIEIERSA-N-KIKMDLHVAKPGVVIGRAGAGIEALKAELEKMII VNIVEVRS---TDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKS-GAKGIKVSASGRLGGAEMARTEGYSEGNVPL- -QTLRADIDYGFAEADTTYGKIGIKVWICMTMTDPIADMLTRIRNANVVKHETVDV-PASNMKKELARILLEEGFIRGYD VIE----D---G----KQGIIRIQLKYG---QEG-------E---RVITGLKKISKPGMRVYAANHEIPKVLNGLGISVI STSKGILTDKQARKENVGGEVICYVWAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLPTEKQVVTILRA VHKYKYSR-EQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIKLRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYN KRVKRTKKFKAHDEK--NICNIGDRVKIMETRPLSKDKRFRLVEVVEKV------------------------------- -MSRST-KKGPFVHA-RLLKKIEAMNA---SGNKE----VIKTWSRSSTVFPQMVENTIAVHDGRKHVPVYITE-DMVGH KLGEFVPTRTFKGHK------D--DEK----SNK------RK >FIRM_Clostridium_kluyveri_DSM_555 Concatenation of 2 sequences MAVKGFKPTTPSRRHMTVNTFEE-ITTD------------IP-EKSLLVALKRSGGRNAHGKITVRH-IGGGAKRK---- YRIIDFK-R--NK-DGIPAKVSTIEYDPNRSAFIALVTYA-DGEKRYIIAPVGLKVGDVIVSGA-D-SD-IKVGNCLPIV NIPVGTTIHNIELQAGKGAQLVRSAGTSAQLMAK--EGKYATLRLPSGEVRYVRIECRATIGTVSNLTHEIINIGKAGRK -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGKS-P--VGHPGPLTP---WGKPALGLKTR-KNKKYSD-K-FIIKRK --------------------------------MKK---A-ILGKKLGMTQIFN-ENGR---------VIPVTVIEAGPCV VVQKK----TEE----K--DGY--KSIQIGF-------GD--IVNK----------PLKGHFK----------------- ---SG-VSLKRFLKEFKV--------DNIDEY-----EV---GQ-EIKA--D-I-FAEGDRIDVSGISKGKGFQGVIRRW NAQR-GPMSHGS-KFHRA-VGSMGAS-SDPS-RTFKNKKMPGHMGNKNTTVLNLQVAKVIPEKN---------------- ----------IILIKGG-VPGPNKSFVSIK-MPIVGLFN-KEGQKI-TDFELSDKVF----GV-EV-NQYVMHQVVVALL ANKRQGTQSAKTRAE--------VS-GGGIKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- IHGGVVFAVK-P-RSYRISVPKSARRLAMKSALSSKVEEN----------------Q-IVVLESL----EMD-T------ --PKTKLIV--TAESN--Q---NVYKSARNIQGVS-V---------------IPVNNLNVYDLLKFDK----LIITKDAV SKIELRLQEKYEKEV----VPALMDKFGYKNIMQAPKLEKIVINMGVG-EAKDNPKVLESAVNDLTIITGQKPVLTRAKK SIANFKLRENMAIGCKVTLRKQYMYEFADKLMNVALPRVRDFSGVSD-KSFDGRGNYSLGIKEQLIFPEIE-----YDKI DKVRGMDIVFVTT-----------------------ANTDEEAKELLRLFGMPFMSRIG-K--LPIAIPAGVTFT-V--- -T-P-DN-VVTVKGSKGQLVKAM--AK-D--INIAVED-NS--VVV---TR-N--DDEKKSR-SLHGLTRALINNMVVGV TEGYSKTLELIGVGY--RAQLQG-KK--LVMN--LGFSHPVEIEA-V-E-GVTFETP--A-ATKVVIKG-IDKELVGNVA ADIRSWR------KPEPY---KGKGIKYDNEVIRRKEGK----------MIQQQTLLKVADNSGAKEIMCIRVLG-SKRK W--GNIGDIIVASVKSATPG-G-------VVKKGEVVKAVIVRSARGLRRTDGSYIKFDENAAVIIK-EDKQ-PRGTRIF GPVARELR-DKDFTKILSLAPEVLMK-L--HELKPAEGS-RKSRKRIG-RGTGSGL-GRNAGKGEKGQKARAGGG-V--- -RIGF-E-GGQMPLYRRVPK-RG--FTNLNVERLITPELLIEK-RMIRLK---------ILG--NGE-L-Q-K-K-LTV- KAVKFTKAAAQKIEAAGGKV-K---VQR--GRM---KGKA-TRGNSIAYG----------DYAIQAT--ECAWITNNQIE SARIAINRYI------RRGGKLWIKIFPDKPVTEKPAETRMGSGK---------GSPEYWVAVVKP-GRILFEL--SG-- VPEETAREAMRLASHKLPIKTKF-VKKKLRKKRHLRVRKKI---FGTSEVPRLSVYRSEKNIYAQIIDD---I--KGTTL VSASSV-DKDF-K-------GNG-SNKEAAKVVGKMIADK--AIEKG-IKEVVFDRGGYIYH--GRVQNLAEGAREGGLQ F--------------------------------------------------------------ME-AKAIAKYVRMSSMK VRVVLNLVRGKNVNEAFAILKYT---------------------------------PRDAAVVVNKLLKSAVAN----A- ENNL-DLNRDTLYISEAYACEGPTLKRFQPHAQGRAFRINKRSSHITLIVKEKVHVRKKDTVMIISGK------DK-GKT GEVLAVMPKVS--KVL--VSGINIVSKHQK----PN--KQ-NME-GGIIRKEAAIYSSKVM-LYCEKC-------KS--V --TRISHKI---LE--------DGKVR---VCKKCG---ETL--MGQKVHPHGLRVG--II-KEWDAKWYA------DKK N--FADNLVEDNKIRKFV--KKKGA-----IAGISKIQIERAA-K-RIKLNIFTAKPGMIIGKGGQGIEALKTELKKIIL INIVEVKV---AEADAQLMAENIALQLEKRISFRRAMKQTIQRAMKS-GIKGVKTTCSGRLGGAEIARSESYHEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRIRNANVVRHEVVEV-PSSTIKKAVLNIMLQEGYIKNLE EYA----D---G----SVNMIRLSMKYG---KNK-------E---RVITGLKRISKPGLRVYCRKEEIPKVLNGLGVAII STSKGIVTDREARKLGVGGEVLCYIWMAKQKIRIRLKAFDHTILDQSSEKIVETAKSTGAKVAGPVPLPTEKDVVTILRA PHKYKDSR-EQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKLRKTRIGTVTSDKMDKTIVVAVENRVRHPLYG KIIKKTSKFKAHDEN--NEAKNNDKVLIMETRPLSKDKRWRLVEIVEKA------------------------------- -MSRSV-KKGPYVQE-SLLKKINELNK---KGEKK----VIKTWSRSSTIFPQMIGHTIAVHDGRKHVPVYISE-DMVGH KLGEFALTRTYRGHV------N-KTEK----TTR-------- >FIRM_Clostridium_kluyveri_NBRC_12016 Concatenation of 2 sequences MAVKGFKPTTPSRRHMTVNTFEE-ITTD------------IP-EKSLLVALKRSGGRNAHGKITVRH-IGGGAKRK---- YRIIDFK-R--NK-DGIPAKVSTIEYDPNRSAFIALVTYA-DGEKRYIIAPVGLKVGDVIVSGA-D-SD-IKVGNCLPIV NIPVGTTIHNIELQAGKGAQLVRSAGTSAQLMAK--EGKYATLRLPSGEVRYVRIECRATIGTVSNLTHEIINIGKAGRK -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGKS-P--VGHPGPLTP---WGKPALGLKTR-KNKKYSD-K-FIIKRK --------------------------------MKK---A-ILGKKLGMTQIFN-ENGR---------VIPVTVIEAGPCV VVQKK----TEE----K--DGY--KSIQIGF-------GD--IVNK----------PLKGHFK----------------- ---SG-VSLKRFLKEFKV--------DNIDEY-----EV---GQ-EIKA--D-I-FAEGDRIDVSGISKGKGFQGVIRRW NAQR-GPMSHGS-KFHRA-VGSMGAS-SDPS-RTFKNKKMPGHMGNKNTTVLNLQVAKVIPEKN---------------- ----------IILIKGG-VPGPNKSFVSIK-MPIVGLFN-KEGQKI-TDFELSDKVF----GV-EV-NQYVMHQVVVALL ANKRQGTQSAKTRAE--------VS-GGGIKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- IHGGVVFAVK-P-RSYRISVPKSARRLAMKSALSSKVEEN----------------Q-IVVLESL----EMD-T------ --PKTKLIV--TAESN--Q---NVYKSARNIQGVS-V---------------IPVNNLNVYDLLKFDK----LIITKDAV SKIELRLQEKYEKEV----VPALMDKFGYKNIMQAPKLEKIVINMGVG-EAKDNPKVLESAVNDLTIITGQKPVLTRAKK SIANFKLRENMAIGCKVTLRKQYMYEFADKLMNVALPRVRDFSGVSD-KSFDGRGNYSLGIKEQLIFPEIE-----YDKI DKVRGMDIVFVTT-----------------------ANTDEEAKELLRLFGMPFMSRIG-K--LPIAIPAGVTFT-V--- -T-P-DN-VVTVKGSKGQLVKAM--AK-D--INIAVED-NS--VVV---TR-N--DDEKKSR-SLHGLTRALINNMVVGV TEGYSKTLELIGVGY--RAQLQG-KK--LVMN--LGFSHPVEIEA-V-E-GVTFETP--A-ATKVVIKG-IDKELVGNVA ADIRSWR------KPEPY---KGKGIKYDNEVIRRKEGK-------MFLMIQQQTLLKVADNSGAKEIMCIRVLG-SKRK W--GNIGDIIVASVKSATPG-G-------VVKKGEVVKAVIVRSARGLRRTDGSYIKFDENAAVIIK-EDKQ-PRGTRIF GPVARELR-DKDFTKILSLAPEVLMK-L--HELKPAEGS-RKSRKRIG-RGTGSGL-GRNAGKGEKGQKARAGGG-V--- -RIGF-E-GGQMPLYRRVPK-RG--FTNLNVERLITPELLIEK-RMIRLK---------ILG--NGE-L-Q-K-K-LTV- KAVKFTKAAAQKIEAAGGKV-K---VQR--GRM---KGKA-TRGNSIAYG----------DYAIQAT--ECAWITNNQIE SARIAINRYI------RRGGKLWIKIFPDKPVTEKPAETRMGSGK---------GSPEYWVAVVKP-GRILFEL--SG-- VPEETAREAMRLASHKLPIKTKF-VKKKLRKKRHLRVRKKI---FGTSEVPRLSVYRSEKNIYAQIIDD---I--KGTTL VSASSV-DKDF-K-------GNG-SNKEAAKVVGKMIADK--AIEKG-IKEVVFDRGGYIYH--GRVQNLAEGAREGGLQ F--------------------------------------------------------------ME-AKAIAKYVRMSSMK VRVVLNLVRGKNVNEAFAILKYT---------------------------------PRDAAVVVNKLLKSAVAN----A- ENNL-DLNRDTLYISEAYACEGPTLKRFQPHAQGRAFRINKRSSHITLIVKEKVHVRKKDTVMIISGK------DK-GKT GEVLAVMPKVS--KVL--VSGINIVSKHQK----PN--KQ-NME-GGIIRKEAAIYSSKVM-LYCEKC-------KS--V --TRISHKI---LE--------DGKVR---VCKKCG---ETL--MGQKVHPHGLRVG--II-KEWDAKWYA------DKK N--FADNLVEDNKIRKFV--KKKGA-----IAGISKIQIERAA-K-RIKLNIFTAKPGMIIGKGGQGIEALKTELKKIIL INIVEVKV---AEADAQLMAENIALQLEKRISFRRAMKQTIQRAMKS-GIKGVKTTCSGRLGGAEIARSESYHEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRIRNANVVRHEVVEV-PSSTIKKAVLNIMLQEGYIKNLE EYA----D---G----SVNMIRLSMKYG---KNK-------E---RVITGLKRISKPGLRVYCRKEEIPKVLNGLGVAII STSKGIVTDREARKLGVGGEVLCYIWMAKQKIRIRLKAFDHTILDQSSEKIVETAKSTGAKVAGPVPLPTEKDVVTILRA PHKYKDSR-EQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKLRKTRIGTVTSDKMDKTIVVAVENRVRHPLYG KIIKKTSKFKAHDEN--NEAKNNDKVLIMETRPLSKDKRWRLVEIVEKA------------------------------- -MSRSV-KKGPYVQE-SLLKKINELNK---KGEKK----VIKTWSRSSTIFPQMIGHTIAVHDGRKHVPVYISE-DMVGH KLGEFALTRTYRGHV----NKTEKTTR----VSR-------- >FIRM_Clostridium_novyi_NT Concatenation of 2 sequences MAVKKFRPITPSLRQMTVATFEE-ITTD------------KP-EKSLLVSLNKKAGRNSQGKITVRH-RGGGAKRK---- YRIIDFK-R--TK-DGIPAKVASIEYDPNRTAYIALVVYA-DGEKRYIIAPVGLKVGDVVMSGV-D-AD-IKVGNALPLK NIPVGTVIHNVELQAGKGAQLVRAAGSSAQLMAK--EGKYAILRLPSGEMRYVRIECRAAIGTVSNVTNDIINIGKAGRK -RHL-----GFR-P-TVRGSVMNPNDHPHGGGEGKS-P--IGHPSPLTP---WGKPALGYKTR-KNKKYSD-G-MIIKRR --------------------------------MKK---A-IIGRKIGMTQIFD-ENGK---------VIPVTVVEAGPCA VLQKK----TEE----K--DGY--NAIQVGF-------ED--IANK----------PKKGHFK----------------- ---AG-VSLKRIVREFRL--------ENIDEY-----EV---GT-EIKA--D-V-FAAGDKVDVTGVSKGKGFQGTIKRW NFHR-GPMAHGS-KYHRA-VGSMGAA-SDPS-RTFKNKKMPGHMGNKKSTILNIEVVKVMADKN---------------- ----------VLLIKGG-IPGPNKGYVVIK-MPTVDLYN-IEGQKV-GDLQLAETVF----AV-EV-NEDVLHQVVVAQL ANKRQGNQSAKTRAE--------VS-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IHGGVVFAPK-P-RDYKMSIPKSMRRVAMKSALTSKVNEN----------------E-LVVLESL----ELD-A------ --PKTKLIV--VPESN--E---VIYKSVRNIEGAT-V---------------VPVNNINVYDILKHDK----FIITKEAV SKIESRLQEKYNKEV----IPALMEKFGYKNIMQVPKLEKIVVNMGVG-EAKDNSKVLESAIADLQQITGQKPVITRAKK SVANFKIRQNMPIGCKVTLRKDMMFEFADKLMNIALPRVRDFRGVSA-KSFDGRGNYALGIKEQIIFPEIE-----YDKI DKVRGMDIIFVTT-----------------------AKTDEEARELLRYLGMPFMSRVG-R--LPIEIPNGVNVT-V--- -T-P-EN-VVTVKGPKGELTKAM--HE-D--MNIAVEE-NN--IVV---TR-P--SENVQHK-ALHGLTRALINNMVVGV TQGYEKTLELVGVGY--RAQLKG-KD--LTLN--LGYSHPVEIKA-V-K-GVEYKVP--E-PTKVVVSG-IDKELVGSVA ANIRVWR------KPEPY---KGKGIKYAGEVIRRKEGK----------MIQPQTRLKVADNTGAKEIMCIRVLG-SKRK F--GNIGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRTKRGVRRADGSYIKFDENAAVVIK-DDKQ-PRGTRIF GPIARELREDKEFNKILSLAPEVLMK-L--HELRPAEGS-KKAPKRVG-RGNGSGL-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNVNVSRLVTPEVLKAN-GVISVK---------ILG--NGT-L-E-K-K-LTI- KATKFTKGAVEKIESIGGKA-K---VQR--GRM---KGKA-TRGNFIAYG----------DYAIQAT--ECGWLTSNQIE AARIAINRYI------KRGGKLWIKVFPDKPVTEKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEL--SG-- VPENVAREAMRLASHKLPMKTKF-VRQKARVKRHLRVRNKI---SGTAARPRLAVYRSEKNIYAQIIDD---V--ARITL VSASTL-DKEF-AEKV------G-SNKEAAKAVGTMVAKR--ALEKG-IEEVVFDRGGYVYH--GRVKELADAAREAGLK F--------------------------------------------------------------ME-ARAIAKYVRMSPRK VRVVLDLVRGKNVSEAFAILKYT---------------------------------PKDAATVVLKVLKSAVAN----A- ENNF-NLDVNKLYIAEAYANQGPTLKRFKPRAQGRAYSIMKRTSHVTLVVKEKVHVRRTDKVVVISGK------DK-GKV SEVLAVYPKTS--KVL--VKDANVVTKHVK----PN--RE-NMQ-GGIVKKEAPMNSSKVM-LYCTNC-------NS--A --TRISKKL---LE--------DGKVR---VCKKCG---EIL--MGQKVHPHGLRVG--VI-KDWDAKWYA------NSQ N--FADNLIEDDKIRKFV--KKRSY-----SAGIAKIEIERTA-K-RVKINIHTGKPGMIIGKGGKGIEELKSEILKMVI INIVEVKR---PETDAQLMAENVAQQLEKRISFRRAMKQTIQRAMRS-GAKGVKTACSGRLGGAEIARTEQYHEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWLYMVMTDPIADMLTRIRNANIVRHEVVEV-PSSNVKKSIANILVQEGYVKDIE EYA----D---G----AVPMIRLSLKYN----GK-------E---RIITGLKRISKPGLRVYCKKDNIPKVLNGLGVAII STSKGIVTDREARKLGLGGEVICYVWMANQKIRIRLKAFDHNILDQSAEKIVETAKNTGAKVAGPVPLPTEKDVVTILRA THKYKDSR-EQFEIRTHKRLIDILSPSPKTVDALMRLDLPAGVDIEIKLRKTRIGRVVSDKMEKTIVVAVEGKVRHPLYG KTINRSKKFKVHDEN--NEARINDRVLIMETRPLSKDKRWRLVQIVEKA------------------------------- -MSRSL-KKGPFVAE-SLIKKIEEMNE---KGEKK----VIKTWSRSSTIFPQMLGHTIAVHDGRKHVPVYISE-DMVGH KLGEFVLTRTFKGHV------D-KTEK----GTR-------- >FIRM_Clostridium_perfringens_ATCC_13124 Concatenation of 2 sequences MALKKFNPTTPSRRQMTMPTFEE-VTTN------------AP-EKSLLVSLKKTGGRNAQGKITVRH-HGGGAKRK---- YRIIDFK-R--NK-DGIPAKVATVEYDPNRSAYIALVVYA-DGEKRYILAPVGLKVGDTVVSGP-E-AD-IKPGNALQLK HMPVGTFVHNIELQAGKGGQMVRSAGTSAQLMAK--EGNYATLRLPSGEMRYVRIECKATVGTVSNTTHEIVNIGKAGRK -RHM-----GWR-P-TVRGSVMNPCDHPHGGGEGRS-P--IGRPSPVTP---WGKPALGYKTR-KNKKYSD-R-FIIKRR --------------------------------MKK---A-IIGKKVGMTQIFD-ENGR---------VIPVTVVEAGPCV VVQKK----TVE----T--DGY--DAIQVGF-------GE--LVNK----------PRKGHFK----------------- ---AG-VSLRRTLKEFRM--------EDVANY-----NV---GD-EIKV--D-T-FEIGDKVDVSGVSKGKGFQGTIKRW NASR-GPMSHGS-KFHRA-PGSMGAA-SDPS-RTFKNKRMPGHMGAKNTTVLNLEVVKIMPEKN---------------- ----------IILIKGG-IPGPNKGTVVIR-MPKVGLFN-KEGQQV-GDIQLNEQVF----GV-EV-NKYALHQVVVAQL ANKRQGTQSAKTRSE--------VR-GGGIKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IKGGVVFAPK-P-RDYRMSIPKSMRKVAMTSALTSKVAD-------------------MVVLEDL----TFE-A------ --PKTKLII--TAEVN--E---NVYKSARNIEGVT-V---------------MPVNNINVYDLLNCKT----LMITKEAV NKIENRLQERYEKEV----VPAMMEKFGYKNIMQVPKIEKVVINMGVG-EAKDNPKVLESAVSDLQIIAGQKPVLTRAKK SVANFKIRENMALGCKVTLRKTNMYEFVDKLVSIALPRVRDFRGVSA-KAFDGRGNYSLGIKEQLIFPEIE-----YDKV DKVRGMDIIFVTS-----------------------ANTDEEARELLRFLGMPFMSRVG-K--MPIAIPAGVTVT-V--- -T-P-EN-VVTVKGPKGELVKAM--HK-D--INIAVED-AQ--VVV---TR-P--SDVKEHR-ALHGLTRALLNNMVVGV SQGFSKTLELNGVGY--RAQLQG-KK--LVMN--LGYSHPVEVEA-V-D-GVDFKLD--G-TTKVIVEG-IDKEKVGAVA ANIRSWR------KPEPY---KGKGIKYSDEVIRRKEGK----------MIQQQTLLKVADNSGAKEIMCIRVLG-SKRK F--GNIGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRSVRGLRRADGSYIKFDENAAVIIK-DDKQ-PRGTRIF GPVARELR-DNEFNKILSLAPEVLMK-L--HELRPAAGS-KSAPKRVG-RGTGSGL-GRNAGKGEKGQNARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNINVDRLVTPELLLER-RVVSVK---------ILG--NGN-I-E-K-S-LTI- AGCKLSKQAAEKIVAAGGKV-K---VQR--GRM---KGKA-TRGNFLAYG----------DFGIQAT--TCGWITSNQIE AARIAINRYI------RRGGKLWIKIFPDKPVTEKPAETRMGSGK---------GSVEYWVAVVKP-GRVLFEL--SG-- VDEEKAREAMRLASHKLPVKTKF-VRKEARERRHLRVRKKV---FGTPERPRLSVYRSEKNIYAQIIDD---V--NAVTL VAASSL-DKAI--------EVKG-SNKEAAKLVGELVAKR--AIEKG-INDVVFDRGGYVYH--GRVEALASGAREAGLK F--------------------------------------------------------------ME-AKAIAKYVRMSPTK VGVVLDLIRGKNVNEAFAILKYT---------------------------------PRDAAEVISKVLKSAVAN----A- ENNH-ELDANRLFVAEAHVGHGPTLKRFRPMDHGKAFRINKRTSNITLVVKEKVHVRKNDTVVVISGK------DK-GKT GEVLRVIPKTG--KVV--VKGVNLVKKHQK----PN--RQ-NMQ-GGIIEMEAAINSSKVM-LFCEKC-------KK--A --TRISHKL---LE--------DGKVR---VCKKCG---ETF--MGQKVHPHGLRVG--VI-KDWDAKWYA------DKK N--FADNLIEDQQIRKFI--KKELF-----SAGIAKIEIERSA-K-RVKLNIHTAKPGVIIGKGGSGIERLKASLKNIVL INIVEVKN---AETNAQLMAENIAAQLEKRISFRRAMKQTIQRAMKA-GTLGVKTACSGRLGGAEIARTEQYNEGTIPL- -QTIRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRVRNANSVRHEVVEV-PSSSVKKAIVNILLQEGYLKGVE EYN----D---G----VVPMMRLTLKYG---ANN-------E---RVITGLKRISKPGLRVYCKKDEVPRVLNGLGIALI STSKGLVVDREARKLGLGGEVICYVWMSKQKIRIRLKAFDHTILDQSAEKIVETAKSTGAKVVGPVPLPTEKDVITILRA VHKYKDSR-EQFEVRTHKRLIDIVNPSPKTVDALMRLNLPAGVDIEIKLRKKRLGRVVSDKMDKTIVVAVETKVRHPLYG KTVNRTTKFKAHDEN--NEARFGDRVLIMETRPLSKDKRWRLVEIVEKA------------------------------- -MSRSI-KKGPFVHA-GLLKKIEEMNQ---NGDKK----VIKTWSRSSTIFPQMIGHTIAVHDGRKHIPVYVTE-DMVGH KLGEFVLTRTFKGHI------K--NEK----TSK------RK >FIRM_Clostridium_perfringens_SM101 Concatenation of 2 sequences MALKKFNPTTPSRRQMTMPTFEE-VTTN------------AP-EKSLLVSLKKTGGRNAQGKITVRH-HGGGAKRK---- YRIIDFK-R--NK-DGIPAKVATVEYDPNRSAYIALVVYA-DGEKRYILAPVGLKVGDTVVSGP-E-AD-IKPGNALQLK HMPVGTFVHNIELQAGKGGQMVRSAGTSAQLMAK--EGNYATLRLPSGEMRYVRIECKATVGTVSNTTHEIVNIGKAGRK -RHM-----GWR-P-TVRGSVMNPCDHPHGGGEGRS-P--IGRPSPVTP---WGKPALGYKTR-KNKKYSD-R-FIIKRR --------------------------------MKK---A-IIGKKVGMTQIFD-ENGR---------VIPVTVVEAGPCV VVQKK----TVE----T--DGY--DAIQVGF-------GE--LVNK----------PRRGHFK----------------- ---AG-VSLRRTLKEFRM--------EDVANY-----NV---GD-EIKV--D-T-FEIGDKVDVSGVSKGKGFQGTIKRW NASR-GPMSHGS-KFHRA-PGSMGAA-SDPS-RTFKNKRMPGHMGAKNTTVLNLEVVKIMPEKN---------------- ----------IILIKGG-IPGPNKGTIVIR-MPKVGLFN-KEGQQV-GDIQLNEQVF----GV-EV-NKYALHQVVVAQL ANKRQGTQSAKTRSE--------VR-GGGIKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IKGGVVFAPK-P-RDYRMSIPKSMRKVAMTSALTSKVAD-------------------MVVLEDL----NFE-A------ --PKTKLII--TAEVN--E---NVYKSARNIEGVT-V---------------MPVNNINVYDLLNCKT----LMITKEAV NKIENRLQERYEKEV----VPAMMEKFGYKNIMQVPKIEKVVINMGVG-EAKDNPKVLESAVSDLQIIAGQKPVLTRAKK SVANFKIRENMALGCKVTLRKTNMYEFVDKLVSIALPRVRDFRGVSA-KAFDGRGNYSLGIKEQLIFPEIE-----YDKV DKVRGMDIIFVTS-----------------------ANTDEEARELLRFLGMPFMSRVG-K--MPIAIPAGVTVT-V--- -T-P-EN-VVTVKGPKGELVKAM--HK-D--INIAVED-AQ--VVV---TR-P--SDVKEHR-ALHGLTRALLNNMVVGV SQGFSKTLELNGVGY--RAQLQG-KK--LVMN--LGYSHPVEVEA-V-D-GVDFKLD--G-TTKVIVEG-IDKEKVGAVA ANIRSWR------KPEPY---KGKGIKYSDEVIRRKEGK----------MIQQQTLLKVADNSGAKEIMCIRVLG-SKRK F--GNIGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRSVRGLRRADGSYIKFDENAAVIIK-DDKQ-PRGTRIF GPVARELR-DNEFNKILSLAPEVLMK-L--HELRPAAGS-KSAPKRVG-RGTGSGL-GRNAGKGEKGQNARSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNINVDRLVTPELLLER-RVVSVK---------ILG--NGN-I-E-K-S-LTI- AGCKLSKQAAEKIVAAGGKV-K---VQR--GRM---KGKA-TRGNFLAYG----------DFGIQAT--TCGWITSNQIE AARIAINRYI------RRGGKLWIKIFPDKPVTEKPAETRMGSGK---------GSVEYWVAVVKP-GRVLFEL--SG-- VDEEKAREAMRLASHKLPVKTKF-VRKEARERRHLRVRKKV---FGTPERPRLSVYRSEKNIYAQIIDD---V--NAVTL VAASSL-DKAI-EVKG--------SNKEAAKLVGELVAKR--AIEKG-INDVVFDRGGYVYH--GRVEALASGAREAGLK F--------------------------------------------------------------ME-AKAIAKYVRMSPTK VGVVLDLIRGKNVNEAFAILKYT---------------------------------PRDAAEVISKVLKSAVAN----A- ENNH-ELDANRLFVAEAHVGHGPTLKRFRPMDHGKAFRINKRTSNITLVVKEKVHVRKNDTVVVISGK------DK-GKT GEVLRVIPKTG--KVV--VKGVNLVKKHQK----PN--RQ-NMQ-GGIIEMEAAINSSKVM-LFCEKC-------KK--A --TRISHKL---LE--------NGKVR---VCKKCG---ETF--MGQKVHPHGLRVG--VI-KDWDAKWYA------DKK N--FADNLIEDQQIRKFI--KKELF-----SAGIAKIEIERSA-K-RVKLNIHTAKPGVIIGKGGSGIERLKASLKNIVL INIVEVKN---AETNAQLMAENIAAQLEKRISFRRAMKQTIQRAMKA-GTLGVKTACSGRLGGAEIARTEQYNEGTIPL- -QTIRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRVRNANSVRHEVVEV-PSSSVKKAIVNILLQEGYLKGVE EYN----D---G----VVPMMRLTLKYG---ANN-------E---RVITGLKRISKPGLRVYCKKDEVPRVLNGLGIALI STSKGLVVDREARKLGLGGEVICYVWMSKQKIRIRLKAFDHTILDQSAEKIVETAKSTGAKVVGPVPLPTEKDVITILRA VHKYKDSR-EQFEVRTHKRLIDIVNPSPKTVDALMRLNLPAGVDIEIKLRKKRLGRVVSDKMDKTIVVAVETKVRHPLYG KTVNRTTKFKAHDEN--NEARFGDRVFIMETRPLSKDKRWRLVEIVEKA------------------------------- -MSRSI-KKGPFVHA-GLLKKIEEMNQ---NGDKK----VIKTWSRSSTIFPQMIGHTIAVHDGRKHIPVYVTE-DMVGH KLGEFVLTRTFKGHI------K--NEK----TSK------RK >FIRM_Clostridium_phytofermentans_ISDg Concatenation of 2 sequences MGIKTFNPYTPSRRHMTGSDFAE-ITTS------------TP-EKSLVVSLKKNAGRNNQGKITVRH-QGGGSRRK---- YRIIDFK-R--KK-DGISAVVKTIEYDPNRTANIALICYA-DGEKAYILAPNGLQVGQTVMNGA-T-AE-IKVGNCLPLA NIPVGSQIHNIELYPGKGGQLVRSAGNSAQLMAR--EGKYATLRLPSGEMRMVPISCRATLGQVGNIDHELVTLGKAGRV -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGKT-G--IGRPGPVTP---WGKPALGLKTR-KKNKQSN-K-MIMRRR --------------------------------MKK---A-ILATKIGMTQIFN-ENGV---------LTPVTVLQAGPCA VTQVK----TVD----N--DGY--AAVQVGF-------GD--IVNK----------PQKGHFK----------------- ---AG-VANKRFLKEFRF--------ENAADY-----TV---GQ-EIKV--D-I-FTAGDKIDATGTSKGKGFQGAIKRH GLSR-GPMGHGS-KFHRH-AGSNGAA-TTPG-RVFKGKHMPGQMGNVKVTVQNLEVVKIDVDNN---------------- ----------LILVKGA-VPGPKKAMIMLK-MANVKVYN-IEGKEV-GSLELNDAIF----GV-EV-NEHLMHMAVVSQL ANKRQGTQSAKTRAE--------VS-GGGRKPW---------RQKGTGHAR--------QGS---TR-SP----QW---- KGGGVVFAPK-P-RDYSFKMNRKEKSLAIKSALTSRVEAQ----------------K-LIVLDSM----NMD-E------ --IKTKLVV--LDKKD--E---NVILSARNIPTVR-T---------------ATSNAINVYDIVKYDT----LVITKDAV AQIETRLKEIYKNEI----MAGMQKKFGYKNEMQIPKLDKIVINMGVG-EAKDNAKALEAAVKDMEIIAGQKAVITKARK SVANFKLREGVAIGCKVTLRGEKMYEFADRLINLALPRVRDFRGVNP-NAFDGRGNYALGVKEQLIFPEIE-----YDKV DKVRGMDVIFVTT-----------------------AKTDEEARELLTLFGMPFMSRIG-R--MPIAIPAGVTVE-V--- -A-E-NN-KVTVKGPNGTLDRVL--PA-E--MDIKVEG-DT--VVV---TR-P--NELKRMK-SLHGLTRTLIANMVTGV TTGYQKVLEINGVGY--RAAKNG-KE--LTLT--LGYSHPVVMKD-P-E-GVETILE--G-QNKITVKG-IDKEKVGQYA AEIRDKR------RPEPY---KGKGIKYSDEVIRRKVGK----------MIQSESRLKVADNSGAKELLCIRVMG-STRR Y--ANIGDIIVASVKDATPG-G-------VVKKGDVVKAVVVRTVKGARRKDGSYIRFDENAAVIIK-DDKN-PKGTRIF GPVARELR-EKQFMKIVSLAPEVLMN-L--TDLRPADGSKQSGNFRRG-RGHGSGN-GKTAGKGHKGQKARSGAP----- -RVGF-E-GGQMPLYRRLPK-RG--FKNVNVSMLVTLESLREI-GIISVK---------ILG--NGE-L-T-K-K-LNV- KVSAFSESAIEKIKALGGNA-K---QFR--GSM---AGKA-MRGNTISHG----------EYGIVAM--ESAWIKSNQIE AARIAMTRYI------KRGGKVWIKIFPDKPVTTKPAETRMGSGK---------GSLEYWVAVVKP-GRVMFEI--AG-- VAEETAREALRLATHKLPVKCKI-VKSEVRIKKHNRIRNRF---SGTPTRPRLAVFRSNNHMYAQIIDD---T--VGNTL VSASTL-EKGV-KAEL----EKT-NDVAAAAMLGTVIAKK--ALEKG-ITTVVFDRGGFIYQ--GKVQALAEAAREAGLN F-------------------------------------------------------------DTR-PSAKLSYARVSVQK ACFVLDAVRGKDVQTALGILAYN---------------------------------PRYASTLIEKLLKSAIAN----A- ENNN-GMDVSKLYIEECYAGCAPTMKRIKPRAQGRAYRILKRLSHITIVLNETTKIKKGDSVKVIAGK------DK-GKE GKVISVSNG----KVL--VEGVNTITKHSK----AS--QA-NPK-GGIIHQEAPIDASNVM-YVQKGK-----------T --TRIGFTT--VDG-------KNGKVR---VAKATG---DII--MGQKVNPHGLRVG--VI-NDWDSRWYA------E-A D--FADNLVEDYNIRTYL--KKKLY-----SAGVAKIEIERAS-D-KLKVIIHTAKPGVVIGKGGAEIEKLKVEITQYLN LEIKEIKK---PDVCAQLVAESIAAQLENRISFRRAMKSTMSRTMRS-GAKGIKTAVSGRLGGADMARTEFYSEGTIPL- -QTLRADIDYGFAEADTTFGKLGVKAWIYMTMSDPIADMLTRIRNANTAKHDTVDV-PASKMKIAIAEILLKEGYIKSFE IEE----V---G----SFKTIHITLKYG--KDKN-------E---KVITGLKRISKPGLRVYANSTELPRVLGGLGVAII STNKGVLTDKAARNANVGGEVLAFIWMANQVMRITLKAYDHHLIDASAGKIIETVKKTGSKVSGPVPLPTKKEIVTVLRA VHKYKDSR-EQFEQRTHKRLIDIIAPTQKTVDALSRLEMPAGVYIDIKMRKTRTGKVVSDKMDKTIVVAVVDNVKHPLYG KIVKRTYKLKAHDEN--NECQIGDRVKVMETRPLSKDKRWRLVEIIEKA------------------------------- -MARSL-KKGPFADD-HLLKKVDDLNK---TGSKT----VIKTWSRRSTIFPQMVSHTIAVHDGRRHVPVYVTE-DMVGH KLGEFVATRTFRGHG------K--DEK----KSR------K- >FIRM_Clostridium_tetani_E88 Concatenation of 2 sequences MGIKLFKPTTPSRRNMSANTFEE-ITTD------------KP-EKSLLVSLKRTGGRNSQGKITVRH-RGGGAKRK---- YRIIDFK-R--DK-DGIPAKVATIEYDPNRTAFIALVVYT-DGEKRYIIAPQGLKVGDVIVSGP-D-AD-IKAGNCLPIK NIPVGTFVHNIELASGKGAQLVRSAGGSAQLMAK--EGNYATIKLPSGETRYVRIECRATIGTVSNVKHEIMSIGKAGRK -RKM-----GFR-P-TVRGSAMNPCDHPHGGGEGRT-P--IGMSSPVTP---WGKPALGYKTR-KTKKYSD-R-LIIKRK --------------------------------MKK---A-IIGRKLGMTQIFD-ENNR---------VVPVTVVEAGPCT VVQKK----SVE----K--DGY--EAIQVGY-------GE--IVNK----------PLKGHFK----------------- ---AG-VGLSRMLREFKL--------ENVSEY-----QV---GQ-EIKV--D-I-FEAGEKIDVTGTSKGKGYQGIIKRW NAHR-GPMSHGS-KFHRA-VGSMGAA-SYPA-RTFKNKRMAGHMGNVKSTVLNLEVVKTIPEKN---------------- ----------LILIKGG-IPGPNKGYVIIR-MPTVGLFN-KEGQKV-GDFQLSDKVF----GV-EV-NKEVLHQVIVAQL ANKRQGTQSSKTRAE--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IKGGVVFAPK-P-RDYSMAIPKSMKRVAMKSALSSKVQEN----------------E-IVILESL----EAD-A------ --PKTKLIV--TEESN--K---NIYKSARNIEGVT-V---------------LPVNNINVYDILRYDK----FIITKDAV SKIEPRLQEKYEKEV----IPALIEKFGYKNIMEVPKLEKIVINMGVG-EAKENQKMLESAVSDLSIIAGQKPIVTKAKK SVANFKIRENMPIGCKVTLRKVKMYEFADKLMNVALPRVRDFRGVSS-KSFDGRGNYSLGVKEQLMFPEIE-----YDKV DKVRGMDIIFVTT-----------------------AKTDEEARELLRFLGMPFMSRIG-R--LPIAIPNGVTVT-V--- -S-P-EN-VVTVKGPKGELTKTM--HP-N--IDIAIEE-NS--VIV---TR-K--NDEKQNR-SLHGLTRSLVNNMVVGV TEGYEKKLELVGVGY--RAQLQG-KK--LVLN--LGFSHPVEIEA-K-E-GVEFQLD--G-TNKITVKG-IDKELVGAVA SDIRSWR------KPEPY---KGKGIKYENEAIRRKEGK----------MIQQQTTLKVADNSGARGIMCIKVLG-SNRR Y--ANIGDIIVASVKSATPG-G-------VVKKGEVVKAVVVRSKKGVRRADGSYIKFDENAAVIIK-DDKQ-PKGTRIF GPVARELR-DKEFNKILSLAPEVLMK-L--HELRPAEGS-RKSPKRVG-RGTGSGL-GKTSARGENGQNSRSGGG-V--- -RPGF-E-GGQMPLYRRLPK-RG--FTNINIDRLVTPELLIEK-GVISVK---------ILG--NGE-L-D-K-K-LIV- KATKFSKAAAEKIEAAGGKV-K---VQR--GRM---KGKA-TRGNFIAYG----------DYGIQAT--ECGWITSNQIE SARIAINRYI------RRGGKLWIKIFPDKPVTQKPAETRMGSGK---------GTPEYWVAVVKP-GRVLFEL--TG-- VDEETAREAMRLAAHKLPVKTKF-VRQKGREKRHLRIRKNI---FGTPEMPRLSVYRSEKNIYAQIIDD---L--NGVTL VAASSL-DKEF--------DAKG-SNKDGAKLVGELVAKR--AIEKG-VTKVVFDRGGYIYH--GRVQELAEGAREAGLQ F--------------------------------------------------------------ME-AKAIAKYVRMSPRK VGVVLDLVRGKDVNEAFAILNYT---------------------------------PREAAVVINKVLKSAVAN----A- ENNL-ELDPSRLYVAEAYACQGPTLKRYQPHAQGRAFRINKRTSHVTLVVKEKVHVRKQDTVMVISGK------DK-GKI GEVLRVLPKSG--KVV--VKDVNVVTKHQK----PS--RE-NMQ-GGIIHVEAPIYSSKVM-LYCTKC-------KS--V --TRINHKI---LD--------DGKVR---VCKKCG---ETF--MGQKVHPHGLRVG--VI-KDWDAKWYA------DKK N--FSDNLVEDNNIRNFV--KKKVY-----AAGISKIEIERAG-K-RVKLNIYTAKPGMVIGKGGQGIEALKGELKNIIL INIVEVKS---AETDAQLMAENVAQQLEKRISFRRAMKQTIQRAMKS-GIKGVKTACSGRLGGADIARTEFYHEGTIPL- -QTLRADIDYGFAEADTTYGKIGVKVWVYMVMTDPIADLLTRVRNANIARHEAVEI-PASNIKKAIANIMLQEGYITDLE EYN----D---G----AVPMLKITMKYG---QNK-------E---RVITGLKRISKPGLRVYCRKDEVPKVLNGLGTAVI STSKGILPDKEARKLSIGGEVLCYIW------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------ >FIRM_Clostridium_thermocellum_ATCC_27405 Concatenation of 2 sequences MPVKKYNPTSPGTRFMTVSTFEE-ITKK------------EP-EKSLLAPLKKTGGRNSYGRITVRH-HGGGAKRK---- YRIIDFK-R--DK-DGIKAKVAAIEYDPNRTAYIALLHYV-DGEKRYIIAPHGLKVGDIVESGE-N-AD-IKPGNALPLE NIPVGTEIHNIELKPGKGGQLVRSAGNVAQLMAK--EGNYAQIRLPSGEVRMVSLKCKATIGQVGNIDHENVSIGKAGRK -RWM-----GIR-P-TVRGVVMNPVDHPHGGGEGKS-P--IGRPSPVTP---WGKPTLGYKTR-KKNKASD-K-FIIKRR --------------------------------MEK---F-MLGRKIGMTQVFD-EDGL---------LIPVTVIEAGPIT VVQKK----KPE----T--DGY--NSVRVAF-------GD--VLNK----------PEKGLFK----------------- ---LG-IAPKKYIREFRV--------DDPDKY-----EL---KQ-EIKV--EEM-FQPGDRVDVTGISKGKGFAGVIKRF GNRR-GKETHGS-MYHRR-VGSMGAN-TNPA-RVFKGKKLPGHMGVERVTVQNLDVVKVDAERN---------------- ----------LMLVKGA-VPGAKGGLLMIK-MPKVDVYD-INGKVV-GEINLRDDIF----GI-EV-NKHAIHQVIVNQL ANRRQGTQSTKTKSE--------VR-GGGRKPW---------RQKGTGRAR--------HGS---IR-SA----QW---- VKGGIALGPK-P-RSYKYAVPKKLRRLALKSALSSKVNEN----------------E-LLVLDSL----NFD-E------ --IKTKVLV--LADKN--R---NVELSARNIPGLK-T---------------LFVNTMNVYDIIRHDK----FIITKDAV AKVEPRLKDKYFNEV----VPALQAKFKYKSPMQVPKLEKIVLNMGVG-DVKDNPKAIEAAVNDMALISGQKPVVTKAKK SVAGFKIRQGMSIGCKVTLRGNKMYEFADKLINVSLPRVRDFRGVPV-NSFDGRGNYSLGVKEQLIFPEID-----YDKI DKIRGMDITFVTT-----------------------AKTDEEARELLKLLGMPFMSRIG-R--IPVAIPKGVDVK-L--- ---GDNN-TLTVKGQKGTLTKQF--HK-D--MIIKVEG-DK--IIV---QR-P--SDEKKHK-ALHGLTRTLINNMVIGV TQGYEKALEINGVGY--RAQKQG-KK--LILT--LGYSHPVEMEE-P-Q-GITVEVP--A-PNKIVVKG-ADKQAVGEFA AKIRSKR------EPEVY---KGKGIKYEDEVIRRKEGK----------MIQVQTMLKVADNTGAKKVMCIKVLG-SKRK Y--ANIGDVIVASVKDATPG-G-------VVKKGDVVRCVIVRSKRGIRRPDGSYIRFDENAAVLIR-EDKN-PRGTRIF GPVARELR-DKEYMKILSLAPEVLMK-L--FELQPAPGS-KKLPKRKG-RGHGTGN-GKTAGRGHKGQNARSGGG-V--- -RPGF-E-GGQMPLYRRVPK-RG--FTNVNVSALVTQELLKEK-GIIKVV---------ILG--NGE-L-K-K-K-LTV- KAARFSKTAAEKIEAAGGKV-K---VQR--GRM---KGVA-TRGNKVVHG----------DYGLQAL--EPAWITSNQIE AARIAMTRFI------KRGGKVWIKIFPDKPVTKKPAETRMGSGK---------GSPEYWVAVVKP-GRVLFEI--AG-- VSEEVAREALRLAMHKLPIKCKF-VSNVARLRKHKRVRKKV---FGTPERPRLNVYRSLTNIYAQVIDD---T--VGRTL VSASSL-EKEI-KSKL----GYC-GNKQAAREVGKLVAQR--ALANG-IKRVVFDRGGYIYH--GRVKELAEGAREAGLE F-------------------------------------------------------------KDQ-GKAILRYARISPRK VRIVLDLIKGKDIDEAYAILRYT---------------------------------PKAASSILFKLLKSAEAN----A- TNNN-GLNRDNLYVAEAYADQGPTLKRILPRARGSADRIRKRTSHITLVVKEKVHVKKGDTVVLLTGK------EA-GKK GKVLEVNTKDG--TVI--VEGMNIVKKHQK----PR--SQ-YQQ-GGIINKEAPIHASNVM-LVCPKC-------GK--P --TKVRRRI---LE--------NGKIR---ECKKCN---GTI--MGQKVNPHGLRIG--II-KDWDTKWYA--------N DKNFSEYLVEDFKIRKFI--KNKLY-----SAGISRIEIERAA-N-KVKINVHAAKPGLIIGKGGAGIEELRKQLEKMIL INITEIKV---PELDAQIVAENIASQLEKRISFRRAMKQAMARAMRL-GAKGIKTAVSGRIAGAEIARTEHYHEGTIPL- -QTLRADIDYGFAEANTTYGKLGVKVWIYMQATDVIADMLTRIRNACSAKHETVDI-PASNIKRAIANILLEEGYIKGIE EID----D---G----KQGVLRLKLKYT---ANK-------Q---NVISGLKRISKPGLRVYAGKSEIPKVLGGLGIAII STSKGIMTDKKARAEGVGGEVLAFVWANKQKIRIRLKAFDHQVLDQSAEKIVETAKRTGAKVSGPVPLPTEREVITILRA PHKYKDSR-EQFEMRTHKRLIDILLPTPKTVDALMRLDLPAGVDIEIKLRKVRVGKVTSDKMDKTVVVSIETSEKHPLYK KFVKRTYKLKAHDEN--NECKIGDIVKVMETRPLSKEKRWRVVEIIERA------------------------------- -MSRSV-KKGPYVDP-KLLKKIEEMNA---KNEKK----VIKTWSRASTIFPQMVGHTIAVHDGRKHVPIYISE-EMVGH KLGEFAPTRTFKGHG------A-HTEK----STA------LK >FIRM_Coprothermobacter_proteolyticus_DSM_5265 Concatenation of 2 sequences MPVRRYKPVTSSTRHRVVIDYKSVITKT------------EP-EKSLLAPLKKSGGRNNAGRISVRF-RGGGHKRR---- YRIIDFK-R--DK-DGIPGKITSIEYDPNRTAFIALVTYA-DGEKRYILAPDEIEVGDVIISGE-E-AP-IRVGNALPLS KIPTGTTIHNIELYPGRGGQLVRSAGTWAQLMAK--EGDYAHVRLPSGEIRLINVKCKATIGRVSNLDHENVSSGKAGRT -RWL-----GRR-P-QVRGTAMNPVDHPHGGGEGKS-P--IGHPSPLSP---WGWKTLGWKTR-RGKKPSD-K-FIVKRR --------------------------------KGI---G-LLGKKIGMSRFID-EKGV---------FIPVTLIKAGPNY VVNVK-----KD----S--KGR--ESVALGF-------EV--VLNK----------PQLGVLK----------------- ---AG-VPPVRFVREFRYP---G---ISE-KF-----EV---GQ-EVNV-AD-V-FADGELVDVIGTSKGRGFAGAMKRW GFAG-GPKTHGTRGWHRR-VGAIGNR-TYPG-EVKPGKKMSGHYGNSQVTVRNLKIVKVIPEQN---------------- ----------IIAVKGS-VPGSRNGFVCIR--MQLPVFD-VNGAEV-AYEDVNENLV----AT-PV-RGRLLHLNVVRVL SGKRHGTASTKKQGE--------VA-GSTRKPW---------PQKHTGRAR--------HGY---MR-SP----IW---- RKGAVAFGPK-P-RDWTKDVNKKQVKLAMASCFGYRLKNG----------------E-LLLIDAN----SFN-------- --GKTRTVV--SLAGE--Q---GVRRACQNLENVY-Y---------------VPVEKVNAYDLLKGDA----VIMTQSAW VRAQMSLKEKYETEV----RPYMMKKFGYKNAMQVPKVVKVTLNRGLG-EALQNPRAIEVTTKEFEIITGQKPLVRRSKK NIAAFKLRKGAPIGVSVTLRKDKMWNFMEHLINDVLPRVRDFRGLNP-RSFDGRGNYNFGLLEDLVFPEIS-----YDMI DKTRGLGISITTT-----------------------AKTDEEAFELLKALGFPFMSRIG-K--KPVVVPKGVTVT-I--- -D-G--S-TVTVKGPKGTLTRTF--DP-R--IKISLIE-DQ--IIV---ER-T--SEEKEVR-ALHGTTRALIQNMVTGV SEGFSVTLKIRGVGY--RAELKG-KD--LQMS--LGFSHPVVIQS-I-E-GIQFQVP--SAD-TVVVSG-IDKQLVTQVA ANIRRYR------IPDAY---KGKGIWYEGEQRPLKPGK----------MIRPYTKLKVADNTGVKTIQVIRVLG-PRVA Y--GTIGDIVVANVREVLPN-S-------DFKKGDVVKAVVVRLAKEIKRPDGTCVKFDDNAAVIID-QLGE-PSGTRVF GPVARELR-EKGYLKIISLAPEVLMR-L--HTLQPAPGA-KSTRKRVG-RGTSSGH-GKTSGFGHKGQKARSGRV-G--- -KRGF-E-GGQTPLYKKLPKIMR--FKNVNVEKLVDIGTLVDT-GLVSVK---------ILG--QGE-I-T-K-A-LQV- KVHAISKSAKEKIEAAGGSV-K---NHL--PHI---KGKE-TRGLKLAFG----------DYGIQAV--GRGYVDSRMIE SCRVIMAKNI------GKTGKYWIRIFPDVAWTKKPLEVRMGGGK---------GDPEKWIFPVKP-GRIMFEL--TG-- VDEDTAKHIARLIGFRLPFEVRL-IRAELRRIRHKRIRKHI---TGTAERPRLCVFRSSRHIYAQIIDD---E--NGHTL VCASTL-EKEL-RDQI----KGL-RKTEQAAAIGKLIAQR--ALEKG-IKSVVFDRGGYKYH--GRVKALADASREAGLE F-------------------------------------------------------------QQM-AKATAKYVRISPRK ARLVVDEIRNKSVSEARAILKYS---------------------------------PNKAARFTLKVLNSAVAN----A- VNNN-GLDEERLYVYRVFVDEGPRLKRYYPRAFGRADIMKRRLSHITVIVKEKLNIKTGDLVEVISGK------EK-GKR GKVTKAFPKEN--KVV--VQGVNIVTKATR----PT--QK-DPQ-GGLKKFEAPILANKVM-VVCPKC-------DK--P --TRIGHKF---LE--------DGKVR---VCVRCG---EVL--MGQKIHPYGFRLG--VT-KNWRSRWVA------PFE K--YPEYIVQDEKIRTLI--NKHYG-----HAGISSVEIERLG-N-KMRVIIWTARPGMIIGKQGAEIERLREEIVKLVR IAIYEVKN---PETDAQIVSDSIARQIERRVSYKRAMKQAISRAMRS-GAQGIKIAVSGRLGGAEIARREWFVQGKLPL- -STLKSDVDYGYSIAVTKYGTIGVKCWIY-MVQDTISDLFIRLKNASHARLERVEGIPYGKYQEEILKVLVREGYIKGYE IEE----K---E----GKKYLSVQLKFG---PGK-------Q---PVLNEVRLISVPSRRIYAKKNDIPKVMNGLGIAIL TTSAGVLSDAEARQKGVGGQIICYVWMSAQRIRIKLRSYDHRLLDQSAKRIVEVAKRTGAKVAGPIPLPTDRRVYCVTRS PHIDKDSR-EHFEIKMHKRLIDIIDPTQETVSNLMSLELPAGVDIHLKLRRRFVGVVVSDKMDKTRVVITERMERHPLYK KEMRRTTKFYVHDEN--NASKEGDIVLIEEYRPMSRLKRFNLVKVLGRK------------------------------M AWDKPY-PRGKYTDP-KLLKKVQKMQS---TGDKR----IIKTWSRRSTITPEMVGLTIAVYNGKVHIPVYITQ-QMVGH KLGEFAITRNFRGHG------EVERSS----ALK-------- >FIRM_Desulfitobacterium_hafniense_DCB-2 Concatenation of 2 sequences MPVKGFKPYSPGRRQMTVSTFEE-ITKT------------TP-ERSLLAPLKSKAGRNNQGKLTVRH-QGGGHKRK---- YRLIDFK-R--NK-DSVPAKVASIEYDPNRSANIALLHYL-DGHKAYILAPNGLQVGQMVVSGP-D-AD-IKVGNALPIK NIPVGTLLHNIEMKPGKGAQLVRSAGGSAQLMAK--EGKYATLRLPSGEMRMVHIDCRATIGQVGNLEHENINIGKAGRS -RWL-----GIR-P-TVRGAVMNPNDHPHGGGEGRN-P--IGRN-PVTP---WGKPALGAKTR-KKKNPSN-R-FIVKRR --------------------------------MSK---G-ILGKKVGMTQVFT-EEGH---------LIPVTVVEAGPCY VIQKK----TKA----T--DGY--NAIQVGF-------GA--LANK----------PQKGHVK----------------- ---AS-VKPMRYIREFRV--------DDVDAY-----EI---GQ-EITA--E-V-FAAGDAVDVVGISKGKGFAGMIKRH GAGR-GPMKHGS-KYHRR-TGSLGA--KGPA-RVFKGRNLPGRMGGERVTVQNLKVVRVDADKN---------------- ----------MILVKGA-VPGAKKSLLILK-MPKVQVVN-MQGSPV-GELELDEYVF----GI-EP-NTHVMHQAVVGQL ASQRRGTHSTLLRGE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGAVLFGPK-P-RKYGFSLPKKVRRLALRSALSSKVNEQ----------------K-LIVLEDL----SLN-E------ --AKTRLIV--TDEFM--E---TIDRSARNIAGIK-T---------------TAVEGMNIYDLLNSDV----IVMTKAAV TKTEARLKDKFSSEI----APALQQKFNYKNVMQIPKLEKVVINVGVG-EAIQNSKAIDAAVGDLSKITGQKPVVTRAKK SIAAFKLRTGMPIGTKVTLRGDRMYEFVDRLMNVALPRVRDFHGVSD-KAFDGRGNYTLGIKEQLIFPEIE-----YDKI DKVRGMDIIFVTT-----------------------AKTDEEARELLGMLGMPFMSRIG-K--RPISIPGGVDVN-I--- -E-G--N-VVTVKGPKGTLTKEM--HS-L--INIAVEE-QQ--IVV---TR-P--DDQPLSR-SLHGLTRTLVANMVEGV TKGFSKSLDMVGVGY--RAAKQG-NK--LVLS--VGKSHPVELI--PFE-GIEVEVP--A-QNKIIVKG-MDKELVGDFA AEIRKER------PPEPY---KGKGIKYENEVVRRKAGK----------MIQVQTRLRVGDNSGAKELMCIKVLG-SMRR Y--ASIGDIIVASVKEATPG-G-------VVKKGDVVKAVVVRTKKEIKRKDGTYIRFSENAAVVIK-DDRS-PRGTRIF GPVARELR-DRDFMKIISLAPEVIMK-L--HELKPAQGS-TKAPKRLG-RGIGSGT-GKTSGKGHKGQKARAGGG-V--- -RPGF-E-GGQQPLSRRMPK-RG--FTNLNVRDLVGYESLFEV-GLIKVK---------ILG--TGE-L-T-K-A-LTV- QVDKVSQTAAEKIVAAGGKV-K---QHR--GRM---HGKA-TRGNVITFG----------EYGLVAM--EPAWITNRQIE AARIAMTRYI------KRGGKVWIKIFPDKPITAKPAETRMGSGK---------GSPEYWVAVVKP-GRVMFEL--AG-- VPEEIAKEALRLAMHKLPVKCKI-VRKAIRMKKHKRVRKSV---FGTAERPRLAVFRSLNHIYAQVIND---E--LGVTL ATASSL-DAEF-KAAE----LAG-GNVEGAKKVGELVAKR--AQEKG-VSKVVFDRGGNIYH--GRIAAVAEAAREAGLE F-------------------------------------------------------------MQQ-AKAIARYVRISPRK VRQVVDLIRGKNVSDALAILQFT---------------------------------PKGATEPVTKVLNSAVAN----A- EHNY-DMDTDALIVKEIYVDEGPTLKRIKPRAMGRADQIRKRTSHITVVVVEKIHVKKGDMVMVITGK------DA-GKK GKVLEVFPKKG--RVV--IEKVNIVKRHTK----PS--QS-MPQ-GGIFEKEAPVASSNVM-LFCTEC-------NK--V --TRVSMKV---TE--------AGKVR---VCKKCG---VNL--MGQKVNPKGLRVG--II-RDWEGRWFA------D-K N--YLELLHEDLKVRKFV--KTKLQ-----QAGVPKVEIERAA-N-RVKVSIYAAKPGIVIGRGGTEVENLRKQLEAMVA VNIVEVKK---PELDAQLVAESVAQQLEKRVSFRRAMKQTVQRTMRQ-GGQGIKISCSGRLGGAEIARTEWYSEGKVPL- -HTLRADIDYGFAEANTTYGKIGVKVWIYMAMSDPIADFLTRIRNAGMVYHDKVEV-PASNVKKAIAEILKEEGFIKDVE YIS----D---N----KQGVIRCYLKYG---QNR-------E---RVITGLKRISRPGLRVYAKKDEVPKVLGGLGVAIL STSKGLMTDKRARQEGLGGEVLCYIWMSSQKIRIRLKAFDHKTLDQSAEKIVETAKRTGARVSGPIPLPTEKSIYTILRS PHVNKDSR-EQFEMRTHKRLIDILEPTSKTVDALMRLDLPAGVDIEIKLRKVRVGKVVSDKMEKTIVVAVEMKVRHPLYH RTITQTKKFKAHDEN--NEAKIGDSVVIMETRPISKDKRWRLVEITERA------------------------------- -MSRSL-KKGPYVEG-RLLERVEKMNA---ANEKR----VLKTWSRSSTIFPQMVGHTIAVHEGRKHIPIYITE-DMVGH KLGEFAPTRTYKGHA------G--SEK----SSG------LR >FIRM_Desulfitobacterium_hafniense_Y51 Concatenation of 2 sequences MPVKGFKPYSPGRRQMTVSTFEE-ITKT------------TP-ERSLLAPLKSKAGRNNQGKLTVRH-QGGGHKRK---- YRLIDFK-R--NK-DSVPAKVASIEYDPNRSANIALLHYL-DGHKAYILAPNGLQVGQMVVSGP-D-AD-IKVGNALPIK NIPVGTLLHNIEMKPGKGAQLVRSAGGSAQLMAK--EGKYATLRLPSGEMRMVHIDCRATIGQVGNLEHENINIGKAGRS -RWL-----GIR-P-TVRGAVMNPNDHPHGGGEGRN-P--IGRN-PVTP---WGKPALGAKTR-KKKHPSN-R-FIVKRR --------------------------------MAIVSKG-ILGKKVGMTQVFT-EEGH---------LIPVTVVEAGPCY VIQKK----TKA----T--DGY--NAIQVGF-------GA--LANK----------PQKGHVK----------------- ---AS-VKPMRYIREFRV--------DDVEAY-----EI---GQ-VITA--E-L-FAAGDAVDVVGISKGKGFAGMIKRH GASR-GPMKHGS-KYHRR-TGSLGA--KGPA-RVFKGRNLPGRMGGERVTVQNLKVVRVDADKN---------------- ----------MILVKGA-VPGAKKSLLILK-MPKVQVVN-MQGSPV-GELELDEYVF----GI-EP-NTHVMHQAVVGQL ASQRRGTHSTLLRGE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGAVLFGPK-P-RKYGFSLPKKVRRLALRSALSSKVNEQ----------------K-LIVLEDL----SLN-E------ --AKTRLIV--TDEFM--E---TIERSARNIAGIK-T---------------TAVEGMNIYDLLNSDV----IVMTKAAV TKTEARLKDKFSNEI----APALQQKFNYKNVMQIPKLEKVVINVGVG-EAIQNSKAIDAAVGDLSKITGQKPVVTRAKK SIAAFKLRTGMPIGTKVTLRGDRMYEFVDRLMNVALPRVRDFHGVSD-KAFDGRGNYTLGIKEQLIFPEIE-----YDKI DKVRGMDIIFVTT-----------------------AKTDEEARELLGMLGMPFMSRIG-K--RPISIPGGVDVN-I--- -E-G--N-VVTVKGPKGTLTKEM--HS-L--INIAVEE-QQ--IVV---TR-P--DDQPLSR-SLHGLTRTLVANMVEGV TKGFSKSLDMVGVGY--RAAKQG-NK--LVLS--VGKSHPVELI--PFE-GIEVEVP--A-QNKIIVKG-MDKELVGDFA AEIRKER------PPEPY---KGKGIKYENEVVRRKAGK----------MIQVQTRLRVGDNSGAKELMCIKVLG-SMRR Y--ASIGDIIVASVKEATPG-G-------VVKKGDVVKAVVVRTKKEIKRKDGTYIRFSENAAVVIK-DDRS-PRGTRIF GPVARELR-DKDFMKIISLAPEVIMK-L--HELKPAQGS-TKAPKRLG-RGIGSGT-GKTSGKGHKGQKARAGGG-V--- -RPGF-E-GGQQPLARRMPK-RG--FTNLNVRDLVGYESLFEV-GLIKVK---------ILG--TGE-L-T-K-A-LTV- QVDKVSQTAAEKIVAAGGKV-K---QHR--GRM---HGKA-TRGNTITFG----------EYGLVAL--EPAWITNRQIE AARIAMTRYI------KRGGKVWIKIFPDKPITAKPAETRMGSGK---------GSPEYWVAVVKP-GRVMFEL--AG-- VPEEIAKEALRLAMHKLPVKCKI-VRKAIRMKKHKRVRKSV---FGTAERPRLAVFRSLNHIYAQVIND---E--LGVTL ATASSL-DAEF-KAAE----LAG-GNVEGAKKVGDLVAKR--ALEKG-VSKVVFDRGGNIYH--GRIAAVAEAAREAGLE F-------------------------------------------------------------MQQ-AKAIARYVRISPRK VRQVVDLIRGKNVSDALAILQFT---------------------------------PKGATEPVTKVLQSAVAN----A- EHNY-EMDTDALIVKEIYVDEGPTLKRIKPRAMGRADQIRKRTSHITVVVVEKMHVKKGDMVMVITGK------DA-GKK GKVLEVFPKKG--RVV--IEKVNIVKRHTK----PS--QS-MPQ-GGIFEKEAPIASSNVM-LYCTEC-------NK--V --TRVSVKE---TE--------AGKVR---VCKKCG---VNL--MGQKVNPKGLRVG--II-RDWEGRWFA------D-K N--YLELLHEDLKVRKFV--KTKLQ-----QAGVPKVEIERAA-N-RVKVSIHAAKPGIVIGRGGTEVENLRKQLEAMVA VNIVEVKK---PELDAQLVAESVAQQLEKRVSFRRAMKQTVQRTMRQ-GGQGIKISCSGRLGGAEIARTEWYSEGKVPL- -HTLRADIDYGFAEANTTYGKIGVKVWIYMAMSDPIADFLTRIRNAGMVYHDKVEV-PASNVKKAIAEILKEEGFIKDVE YIS----D---N----KQGVIRCYLKYG---QNR-------E---RVITGLKRISRPGLRVYAKKDEVPKVLGGLGVAIL STSKGLMTDKRARQEGLGGEVLCYIWMSSQKIRIRLKAFDHKTLDQSAEKIVETAKRTGARVSGPIPLPTEKSIYTILRS PHVNKDSR-EQFEMRTHKRLIDILEPTSKTVDALMRLDLPAGVDIEIKLRKVRMGKVVSDKMDKTVVVAVEMKVRHPLYH RTITQTKKFKAHDEN--NEAKTGDTVVIMETRPLSKDKRWRLIEITERA------------------------------- -MSRSL-KKGPYVEG-RLLARVEKMNA---ANEKR----VLKTWSRSSTIFPQMVGHTIAVHEGRKHIPIYITE-DMVGH KLGEFAPTRTYKGHA------G--SEK----SSG------LR >FIRM_Desulfotomaculum_reducens_MI-1 Concatenation of 2 sequences MAVKNYKPTSPGRRFVTFSDFSE-ITKV------------EP-EKSLLEPIKKTGGRNAQGRLTVRH-QGGGHKRM---- FRIIDFK-R--NK-DGIPAKVASIEYDPNRSARIALLNYA-DGEKRYILAPVGLEVGVIVESGP-D-AD-IKVGNCLPLR NIPVGTMVHNIELYPGAGAQMVRSAGAAAQLMAK--EGKYANLRLPSGEMRLVLQECRATIGQVGNLEHENVTIGKAGRS -RHL-----GIR-P-TVRGKVMNPVDHPHGGGEGRN-P--IGRN-PSTP---WGKLAMGVKTR-GNKK-SD-R-LIVKRR --------------------------------MPK---G-ILGKKIGMTQIFN-EAGV---------AIPVTVVEAGPCL VVQKR----TPE----N--DGY--SAIQLGF-------GV--KLNK----------PTKGHLK----------------- ---AG-VRPVRFLRELKV--------DDLEAF-----QV---GQ-EIKA--D-I-FAEGEKVDVVGTSKGKGFAGGIKRH NFHR-GPMAHGS-KYHRR-PGSSAA--KGPA-RTFKGRKLPGHYGVERVTVQNLQVVKVDPERN---------------- ----------LLAIKGA-VPGPRGGLLLVK-MPKVALYN-INGEQV-GEVELKDEVF----GI-EP-HEHVMHEAVNMQL ANQRQGTHDTKTRAE--------VR-GGGRKPW---------RQKGTGRAR--------AGS---SR-SP----IW---- RKGGIVFGPH-P-RDYAISLPKKVRRLALKSALSSKVLDQ----------------N-IIVLDSL----TMD-A------ --PKTKLVV--TATRD--L---NVEKSARNIEGVK-P---------------LKADGVNVYDLLKYTK----LVITKDAV AKIEARLKDKYLNEV----QPNLMQKFGYKNIMQVPKLEKVIINIGLG-EAVQNSKAVDAAVGDLMAITGQRPITTKAKK SIAAFKLRAGMTIGTKVTLRGERMYEFVDRLFNVALPRVRDFRGISD-KSFDGRGNYTMGLKEQLIFPEIE-----YDKI DKVRGMDITFVTT-----------------------AKTDEEARELLKLMGIPFMSRIG-K--KPIPVPQGVDVK-I--- -N-G--N-VISVKGPKGQLEQEF--HQ-D--MNIKLEE-GN--LVV---ER-P--SDAKDHR-ALHGLTRTLLNNMVEGV TNGFQRNLELVGVGY--RAAKQG-NK--LVLT--IGYSHPVEIEP-P-A-GIEIEVP--A-ATKIAIKG-SDKQAVGQLA ANIRAVR------EPEPY---KGKGIKYENEIIRRKAGK----------MIQVQTILKAADNTGARKLMCIRVMG-SLRR Y--ASVGDIIVASVKEATPG-G-------VVKKGDVVKCVVVRTSKEVRRPDGSYIKFDENAAVVIK-DDKT-PRGTRIF GPVARELR-EKDFMKIVSLAPEVIMN-L--SELRPAPGA-RKKPTRKG-QGIGSGL-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQMPLQRRFPK-RG--FTNINLDELVTPELLLEA-GLIKVK---------ILG--DGI-L-E-K-A-LTV- KVHAFSKSAVEKITAAGGKA-K---QHRPRGN----GGVS-KGGREVSFG----------EYGIQAL--EAGWITNRQIE AARIAMTRYI------KRGGKVWIRIFPDKPITQKPAETRMGSGK---------GAPEHWVAVVKP-GRVMFEV--AG-- VPEATAREAMRLAMHKLPVKCKF-VRKAIRAKRRRRVRNKI---LGTAARPRLNVFRSLNNMYAQLIDD---E--TGVTV VAASTL-SPEL-KETF----KNG-GNVEAAKAVGDLVGKL--ALEKG-IKEVVFDRAGYLYH--GRVKALAEAAREAGLD F--------------------------------------------------------------ME-AKAIAKFIRVSPRK ARMVVDLIRGKKVEEALAILRYT---------------------------------PNKAAAAVTKVVKSAAAN----A- EHNN-DMDKEELVVSQIFVDQGPSLKRMMPRAMGRADIIKRRTSHITVVVSDKVHVRKGDTVMVITGK------DA-GKK GKVVTVEPAKN--RVI--VEGVNIVKRHRK----AT--PQ-MPQ-GGIVEKEAPIHSSNVM-LFCNKC-------NK--A --TRIQKKV---LD--------NGKER---ICKHCG---ETL--MGQKVNPKGLRVG--II-KDWEGKWFA-------KR N--YSNLLIEDVKIREYI--KRKLY-----QAGISRIQIERAA-N-RVKVSIHTAKPGIVIGRGGAEVEALRKELEKMVH VNIVEVKT---PEVDAQLVAENIASQLEKRIAFRRAMKQTVQRSLRM-GAKGIKIACSGRLAGAEIARTEWYSEGKVPL- -HTLRADIDYGFAEANTTYGKIGVKVWIYMVMTDPIADFLTRVRNANTVYHDKVEA-PASNVKKAIAEILKQEGYIKDYE SVE----D---G----KQGIIRLYLKYG---ANK-------Q---RVITGLKRISKPGLRVYAKKDQIPRVLGGLGIAIV STSKGIMTDKQARQSGLGGEVICYVWMKNQKIRIRLKAFDHQMLDQSATKIVDTAKRTGAQVAGPVPLPTEKSIYTILRS PHVNKDSR-EQFEMRVHKRLIDILEPTPKTVDALMRLDLPAGVDIEIKLRKTRQGKVVSDKMDKTIVVAVEDRVRHPLYN RTIRKTTKFKAHDEE--NSCRIGDTVRIMETRPLSKDKRWRVIDILERA------------------------------- -MARSL-KKGPFIDD-HLLKKVDEMNE---KGEKK----VFKTWSRRSTIFPQMIGHTIAVYDGRKHIPVYITE-DMVGH KLGEFAPTRTYRGHA----------DK----SER---STGLK >FIRM_Enterococcus_faecalis_V583 Concatenation of 2 sequences MAIKKYKPTTNGRRNMTSSDFAE-ITTS------------TP-EKSLLQPLKNNAGRNNNGRITVRH-QGGGHKRQ---- YRVIDFK-R--NK-DNVAAVVKTIEYDPNRSANIALVHYE-DGVKAYILAPKGLEVGMRLVSGP-E-AD-IKVGNALPLE NIPVGTVIHNIEMKPGKGGQLIRSAGTSAQVLGK--EGKYVLIRLNSGEVRMILATCRATIGSVGNEQHELINIGKAGRS -RWM-----RKR-P-TVRGSVMNPNDHPHGGGEGKT-P--IGRKAPVSP---WGQPAIGYKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------LIPVTVVEATPNV VLQVK----TVE----T--DGY--EAIQVGY-------QD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIKEFKN--------VELGEY-----EV---GK-EIKV--D-V-FQAGDVVDVTGTTKGKGFQGAIKRH GQSR-GPMSHGS-RYHRR-PGSMGP--VAPN-RVFKNKRLAGRMGGDRVTIQNLEVVKVDVERN---------------- ----------VILIKGN-IPGAKKSLITIK-MPNVALFK-QDGTQN-GEITLNEEIF----GI-EP-NESVVYDAIIMQR ASLRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYSYKFPKKVRRLAMKSVLSDKVAEN----------------N-LVAVEGL----SFD-A------ --PKTKLVV--LENGN--D---FAALSARNLPNVS-V---------------VTSDNVSVLDVVSANK----VLATQTAL TQIENRLKEKYIKEV----TPSLVEKFNYSSVMQTPKVDKIVINMGVG-DAVSNAKNLDKAVEELALITGQKPLITKAKK SIAGFRLREGMPIGAKVTLRGERMYEFLDKLVTVSLPRVRDFHGVSK-KAFDGRGNYTLGIKEQLIFPEVD-----YDLV DKVRGMDIVIVTT-----------------------ANTDEESRELLAQLGMPFMSRIG-N--KVVVLPAGVEIK-Q--- -D-G--N-NITVKGPKGELTREF--SS-D--IKMNIEG-NE--VTF---IR-P--NDSKEMK-TIHGTTRANFNNMVVGV SEGFQKALELIGVGY--RAQVQG-NK--LTLN--VGYSHPVEMTA-P-E-GVTFEVP--A-NTQVIVKG-INKEVVGELA ANIRGVR------PPEPY---KGKGIRYVGEFVRRKEGK----------MIQQESRLRVADNSGAREILTIKVLG-SGRK T--ANIGDVIVATVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRADGSYIKFDENAAVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVLMK-L--HELKPAEGS-RQVRNRVG-RGTSSGN-GKTAGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLDTLVTPVVLKEA-GIVKIK---------VLA--DGE-L-T-K-K-LTV- KAAKFSKSAQEAIEAAGGSI-R---EFR--GKM---RGEA-KGGKEVAFG----------EWGLQAT--ESHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKAIGVRMGKGK---------GAPEGWVSPVKR-GKIMFEI--AG-- VPEEVAREALRLASHKLPVKTKI-VKNKTRQKRHRRVRNKI---SGTAECPRLNIFRSNKNIYAQVIDD---V--AGVTL ASASAL-DKEI---------SGG-TKTETAAAVGKLVAER--AAEKG-IKKVVFDRGGYLYH--GRVQALAEAARENGLE F-------------------------------------------------------------ITS-AKATAKTVRTSPRK ARLVIDLIRGKSVADAISILKFT---------------------------------PNKSAGIIEKVLMSAVAN----A- ENNF-DLDVESLVVSEAFVNEGPTMKRFRPRAKGSASPINKRTSHITVVVTE-MFVKKGDKVKVITGK------DK-NKE GVVLAAFPKQD--KVI--VEGVNVVKKHQK----PN--QA-APQ-GGILEVEAPIHVSNVM-VIDPSN-------GE--A --TKVAFKE----V--------DGKVR---VSKKTG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YAEFLHEDLRIRKFI--ATKLA-----DAAVSTIEIERAA-N-RVNISIHTAKPGMVIGKGGSEVENLRKELNKLVH INIVEIKK---PDLDAKLVGEGIARQLENRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARSEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANMVKHETLEV-PASKIKRDIAEILKREGFIRDVE YIE----D---D----KQGVIRVFLKYG---KNE-------E---RVITNLKRISKPGLRAYVKADEVPKVLNGLGIAII STSEGVITDKEARAKNIGGEVIAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGADVSGPIPLPTERSLYTVIRA THKYKDSR-EQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKLRKVYQGRVVSDKMDKTITVVVETKKNHPIYG KRMKYSKKYKAHDEN--NTAKVGDIVKIMETRPLSATKRFRLLEVVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKVEAQQG---AEKKK----VIKTWSRRSTIFPSFVGFTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYRGHV------A--DDK----KTK------R- >FIRM_Exiguobacterium_sibiricum_255-15 Concatenation of 2 sequences MGIKKFKPTTNGRRNMTALDFAE-ITAS------------RP-EKSLTEKLSKKGGRNNQGRLTVRH-QGGGHKRK---- YRIIDFK-R--NK-DGIAGRIATIEYDPNRSANIALVHYI-DGEKRYILAPKGLKVDMQVMSGV-E-AD-IKVGNALPLS NIPVGTLIHNIELKPGKGGQLVRSAGTSAQLLGK--DGKYAIVRLQSGETRMILATCRATVGAVGNEEHELVNIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPLTP---WGKPALGYKTR-KKNKASD-K-YIVRRS --------------------------------MAK---G-ILGTKLGMTQIFN-ESGE---------VVPVTVVSVEGNV VLQLK----TME----V--DGY--EAVQLGF-------GD--IQNK----------PQKGHAK----------------- ---AS-ATPKRFIKEIRT---------SVTDF-----EI---GQ-EIKA--D-T-FAAGEMVDVTGTSKGKGFAGAIKRH NQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKGKLLPGRMGGEQVTVQNLEIVKVDVERG---------------- ----------LLLVKGA-IPGARKSQVVVK-MPKVALLN-QTGTQV-GDIELADAVF----GI-EP-NEAVVYDAIVMQQ ASRRQGTHDTKGRSE--------VR-GGGRKPW---------KQKGTGRAR--------QGS---IR-SP----QW---- VGGGTVFGPT-P-RSYAYKLPKKVRRLALRSALSSKVANN----------------E-FIVLEGL----TID-A------ --PKTKLVV--TADYN--E---TVVLSTRNIPGVT-V---------------VDAAGVNVLDLVAHDK----VIFTKDAV ARVENRLKAKYQDEI----VKVMMEKFNYTSVMQAPKVDKIVINMGVG-DAVTNTKALDMAVEELQLLTGQKPLITKAKK SIAGFKLREGMPIGAKVTLRGERMYEFLDKLINVSLPRVRDFRGVSK-KSFDGRGNYTLGVKEQLIFPEID-----YDRV SKVRGMDIVIVTT-----------------------ANTDEESRELLTALGMPFMSRIG-K--KPVVIPAGVTVT-V--- -E-N--S-TVTVKGPKGELTREF--NP-T--MAINVEG-NE--LTV---TR-P--NDEKANR-TIHGTTRALIANMVEGV NNGFAKTLDIQGVGY--RAQKQG-NK--IVLN--LGYSHPIEYT--P-EQGIEVEVP--T-NTQIIVRG-ISKERVGHVA ALIRSYR------QPEPY---KGKGIRYSDEVVRRKEGK----------MIQQESRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKQATPG-G-------VVKKGEVVRAVVVRTKRGVRRKDGSYIRFDENAAVIIK-DDKS-PRGTRIF GPVARELR-EKDFMKIVSLAPEVLMK-L--HELKPAAGS-RSERNRVG-RGMSSGN-GKTSGRGHKGQKARSGGG-V--- -RPGF-E-GGQNPLFRRLPK-RG--FNNINLDTLVTPELLIET-RAVKVK---------ILS--NGK-I-E-K-K-LTV- KAHKFSEAAKQAIEAAGGTV-R---VHR--GNM---RGKA-KRGTTVHFG----------EFGIQAQ--EASWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHKPYTKKPLEVRMGSGK---------GAPEGWVAVVKP-GKVMFEI--AG-- VSEEIAREALRLASHKLPVKCKF-VKNATRKKRHGRVRRTI---IGTAARPRLNVFRSNKNIYVQVIDD---A--THATL ASASSL-DLEK-----------G-NTTDAASAVGKLAAER--ALEKG-IETVVFDRGGYLYH--GRIKAVAEAAREAGLK F--------------------------------------------------------------MQ-SKASANMVRIAPRK ARLVVDLIRGKQIGEALSILAYT---------------------------------NKAATPIVEKVLKSAIAN----A- EHNF-DMNIENLVVTEAYVNEGPTLKRFRPRAMGRASRINKRTSHVHIVVSE-MHVKKGDKVQVMTGK------DK-GKQ GVVLTAMPKKD--RVI--VEGVNMIKKHSK----PS--QL-NPQ-GGIVEKEAPIHVSNVM-LIDPKT-------GN--P --TRVGFTV----V--------DGKVR---IAKKSG---EAL--MGQKINPTGLRVG--II-KDWESRWFA------D-K D--YADLLHEDYVVREYI--EKRLK-----DASVSKVEIERAA-N-RLNISLHTAKPGMVIGKGGSEIETLRTDITNLVH VNVVEVKN---PDAVAKLVAENIARQLEGRVSFRRAMKQSIQRSMRS-GIKGIKTEVSGRLGGADIARSEKYSEGTVPL- -HTLRADIDYGTAEADTTYGKIGVKVWLHMVMTDPIADMLTRIRNANMVRHEKLEM-PASTIKREVAEILKREGFIRDVE YLE----D---S----KQGTLRVFLKYG---ASN-------E---RVITGLKRISKPGLRVYAKADEIPKVLGGLGIAIV STSKGVMTDKEARQQKVGGEVIAYIWMANEKIRIRLKAYDHRVLDQSAEKIVETAKRSGATVSGPIPLPTEKAIYTVLRA VHKYKDAR-EQFEMRTHKRLIDIVNPTPKTVDALMRLELPSGVDIEIKLRKVLTGRVVSDKMDKTIVVTVETKVKHKLYG KRVNYSKKYKTHDEN--NTAKIGDVVRIQETRPLSKDKRFRLVEVVEKA------------------------------- -MGRSL-KKGPFADH-HLLAKVDKANE---AGDKH----VIKTWSRRSTIFPEFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRSYKGHA------G--NDK----KTK------R- >FIRM_Exiguobacterium_sp_AT1b Concatenation of 2 sequences MAIKKFKPTTNGRRNMTSLDFAE-ITTN------------RP-EKSLTEKLSKKGGRNNQGRLTVRH-QGGGHKRK---- YRIIDFK-R--NK-DGVAGRVATIEYDPNRSANIALINYV-DGEKRYILAPKGIKVGMEIMSGP-E-AD-IKVGNALPLV NIPVGTTIHNIELKPGKGGQLVRAAGASAQIQGR--DGKYVIVRLQSGESRLFLGTCRATIGSVGNEEHELVNIGKAGRS -RWL-----GKR-P-TVRGSVMNPVDHPHGGGEGRA-P--IGRSGPLTP---WGKPALGLKTR-KKNKSSD-M-YILRRR --------------------------------MAK---G-ILGTKLGMTQIFN-EAGE---------VVPVTVVAVEGNV VLQLK----TVD----T--DGY--EAVQLGF-------GD--IQNK----------PSKGHAK----------------- ---AN-ATPKRFIKEVRT---------SVEGY-----EI---GQ-EIKA--D-I-FAAGELVDVTGTSKGKGFQGAIKRH GQSR-GPMAHGS-RYHRR-PGSMG-P-VAPN-RVFKGKLLPGQMGGERKTIQNLEVVKVDVERG---------------- ----------LLLVKGA-IPGARKSNVIIK-MPKVALLN-QTGSQV-GEIELAEAIF----GI-EP-NESVLYDAIVMQQ ASRRQGTHDTKGRSE--------VR-GGGRKPW---------KQKGTGRAR--------QGS---IR-SP----QW---- VGGGTVFGPT-P-RSYSYKLPKKVRRLALLSALSSKVQNN----------------E-IIVLEGL----AFD-A------ --PKTKLVV--TADYN--E---TIALAARNIPGVT-V---------------IDAAGVNVLDLVANDK----VIFTKDAV AKVENRLQEKYKSDI----VKAMMDKFNYDSVMQVPKIEKIVINMGVG-DAVSNSKALDMAVEELTILSGQKPLVTKAKK SIAGFKLREGMPIGAKVTLRGERMYDFLDKLVTVSLPRVRDFRGVSK-KAFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVVVTT-----------------------ANTDEEARELLTLLGMPFMSRIG-K--KPVTIPAGVTVT-V--- -A-N-DN-TVTVKGAKGELSLSA--NP-A--LEIKVEE-NE--LTV---VR-P--DESKESR-TIHGTTRALIANMVQGV SNGFQKTLEISGVGY--RATKQG-NK--LVLN--LGYSHPIEYVA-E-E-GIEIEVP--S-NTQIIVKG-INKERVGHVA AQIRSYR------APEPY---KGKGVRYSDERIRRKEGK----------MIQQESRLKVADNSGARELLTIKVLG-SGRK T--ANIGDIIVATVKQATPG-G-------VVKKGDVVRAVVVRTKRGARRKDGSYIRFDENAAVIIK-DDKS-PRGTRIF GPVARELR-EKEFMKIVSLAPEVLMK-L--HELKPTPGS-RHERNRVG-RGMATGN-GKTSGRGHKGQKARSGGG-V--- -RPGF-E-GGQNPLYRRLPK-RG--FNNVSLDTLVTPELLIET-GVVSIK---------VLA--NGK-L-E-T-K-LTV- KANKFSGAAKEAIEAAGGTV-R---VHR--GKM---RGNA-KRGTTVHFG----------EFGLQAL--EASWITNRQIE SARIAMTRYM------KRGGKVWIKIFPHKPYTKKPLEVRMGSGK---------GAPEGWVAVVKP-GKVMFEI--AG-- VSEEVAREALRLASHKLPVKCKF-VKNAVRKKRHARVRRTI---TGTAARPRLNVFRSSKHIYVQLIDD---A--AQTTL VSASSK-DKAL---DL----TNG-GNVEAAKAVGKLAAER--ALEKG-IDTVVFDRGGYLYH--GRVKAVAEAAREAGLK F--------------------------------------------------------------MQ-AKASANMVRLAPRK ARLVVDLIRGKQVGEALSVLAHT---------------------------------NKAASPVVEKVLKSAIAN----A- EHNY-DMNIENLVVTEAYVNEGPTLKRFRPRAMGRASRINKRTSHIHIVVTE-MHVKKGDTVQVMSGK------DK-GKQ GVILKAMPSKN--RVV--VEGVNVMKKHAK----PS--QA-NPQ-GGILEIEAPIHVSNVM-PLDPKT-------GK--P --TRVGFKV----V--------DGKVR----VAKSG---ESL--MGQKVNPHGLRVG--VI-KDWDSRWYA------E-K D--YADLLHEDFVIREYI--ENKMK-----DASVSKVEIERAA-N-RVNISLHTAKPGMVIGKGGSEIESLRKHITKIVH INVVEVKN---ADAVAKLVAENIARQLEGRVSFRRAMKQSIQRSMRT-GIKGIKTEVSGRLGGADIARSEKYSEGTVPL- -HTLRADIDYGTAEADTTYGKIGVKVWLYMVMTDPIADMLTRIRNANMVRHEKMEL-PASNIKREIAEILKREGFIRDVE YIE----D---A----KQGTLRLFLKYG---ASN-------E---RVITGLKRISKPGLRVYAKADEVPKVLGGLGIAVL STSKGLMTDKEARQQQVGGEVIAYIWMANEKIRIRLKAYDHRVLDQSAEKIVDTAKRSGAKVSGPIPLPTEKSIYTILRA VHKYKDAR-EQFEMRTHKRLIDIVNPTPKTVDALMRLELPSGVDIEIKLRKVFTGRVVSDKMDKTIVVAVETKVRHKLYG KRVNYTKKYKAHDEN--NVAKVGDIVRIAETRPLSKDKRFRLVTVVEES------------------------------- -MGRSL-KKGPFADH-HLLAKVDKLNE---SGEKQ----VIKTWSRRSTIFPEFMGHTFGVHDGRKHVPVFVTE-DMVGH KLGEFAPTRTYKGHG------S---DK----KTK------R- >FIRM_Finegoldia_magna_ATCC_29328 Concatenation of 2 sequences MAIKKYKPTSAGVRGMSVLSFDE-ITKT------------TP-EKSLTVSLNKSGGRNSYGRVTIRH-RGGGAKRK---- YRIIDFK-R--NK-DGIKAVVKSIEYDPNRTANIALLQYE-DGEKRYIIQPVGLKVGDVVESGA-D-VD-IVPGNALPLR NIPVGTTVHNIEMKVGKGAQLVRTAGAEAQLMAK--EGKFAQLRLPSGEFRLIHLDCKATVGQVGNISHELVTIGKAGRN -RHL-----GKR-P-YVRGSAMNPVDHPHGGGEGRA-P--IGRPAPSTP---WGKPALGLKTR-KKNKKSN-K-YIVRRR --------------------------------MKS-----ILGKKIGMTQIFN-EDGS---------VVPVTVIEAGPMV VTQIK----TKE----K--EGY--NAIQVGY-------IE--KVNQ----------PMRGHFK----------------- ---AG-VSFKKHLREFKI--------NDDEQF-----NL---GD-EIKL--D-I-FQDGDVVDVIGISKGKGTQGAIVRH NYSR-GPMGHGS-KSHRV-AGARSAG-SYPA-RVFKGRKGSGKMGHDRVTVQNLKIVKVDNERN---------------- ----------LLLIKGA-VPGNKGGVVTVR-MPKVQILN-QQGENV-GELELNEAIF----GV-DV-NEHVVYEVVKNQL ANKRQGTQSAKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFAPK-P-RDYSYAVPKKVRRLAIKSVLTEKVNDN----------------E-MIVLDKL----NLD-A------ --ISTKLVV--IDKND--D---TLYRSFRNIENVA-I---------------CEAKLINVYDCLKYNS----LVITTDAV KILESRLKEKYTNEV----VPFLVERFKYENIMQVPRLEKIVLNMGLG-SSKENPKAIESAVKELETITGQRPIVTKARK SIANFKLREGMNVGVKVTLRGEKMYDFLDKFMNISLPRVRDFRGISS-KSFDGRGNYAVGIKEQLIFPEIE-----YDMV DQIRGMDIVVVTT-----------------------ANTDEEAKELLDKMGMPFMSRIG-L--KPIEIPNGVEVK-V--- -T-E-DN-LCTVKGPKGELVEQM--PK-E--MIIKVED-NT--ITV---SR-P--SEIKRHK-SLHGLTRTLVFNMIEGV TEGYKKTLIIEGTGY--RAAKQG-KK--LVLN--LGYSHTIEKED-P-E-GISVEVP--E-QHTLIISG-INKQQVGNYA AKIRDLR------GPEPY---KGKGIRYEDEHIRRKVGK----------MIQQESRLRVADNSGAKELLVIRVLG-TKRK Y--AAIGDIVVCSVKSAQPG-G-------MVKKGDVVKAVIVRTTKPLGRADGSYIRFDDNAAVIIK-DDKN-PVGTRIF GSVTRELR-ANNFMKIISLAPEVLMK-L--HNLRPAKGGEVKARKRVG-RGYGSGL-GHNAGRGRDGQNSRSGGG-V--- -RPGF-E-GGQMPLFRRLPK-RG--FKNINIRDLITPEILANA-GFFKVK---------ILG--DGE-I-T-K-K-LTI- KANKFTKSAEEKITKAGGKV-R---VHR--GRM---KGKA-LKGNTLTYG----------DYGIQAL--GSCWLTANQIE AARRAMTRYI------KRGGNIWIKVFPDKPVSKKPIGIRMGSGK---------GAPEYWVAVIKP-GRVLFEM--AG-- VPEDVAREAMRLAQHKLPIKTKF-IKNANRVKRHLRIRKNL---TGTSEKPRLCVFKSNTNIYAQLIDD---V--NHNTL VAASTL-DKDF-SG------ESK-SNKEAAKLVGELIGKK--AIDKG-IEQCVFDRSGYLYH--GKVKELAEGARSAGLK F--------------------------------------------------------------MQ-AKAIAKYVRISPLK VNFICKEIRGKQVDEALAILKFT---------------------------------PKKGARILEKVLNSAIAN----A- EHNF-GLNREDLFVSQAYANNAPVMKRWRPKAKGMAYPILKRSSHVGVVVEE-MKIKNGDTVIVISGK------DK-GKT GNVIEVLAKKN--KVV--VEGVNIVTKHQK----AN--GR-GVE-SGLIKKEAPIDVSNVM-YYDAKN-------KK--G --TRLGYKF----E--------DGKVR---FMKSNN---ETI--MGQKVNPKGLRVG--VI-KDWDSRWFA------DKK D--FGDYLVEDHKIRELI--KKESF-----SAGISSVSIERAS-N-KIKVTINTAKPGMVIGRQGAGVEELKNKLEKLLI INVEEIKF---QDLDAQLVAENIASQLERRISFRRAMKQTMQRSMRA-GALGIKTMVSGRLGGADMARSEGYSEGTIPL- -QTLRAAIDYGFAEADTTYGKLGVKVWLY-MMTDPIADMLTRIRNAVNAKHKVVEV-PASNIKKSIAQILLDEGFIDGFN VTE----D---G----KQGIITIDLKYG---PNE-------E---KVISGIKRISKPGLRVYARANEVPKVLGGLGIAIV STSKGLVTDKVARKEGIGGEVICYVWMANQKIRIRLRAYDHELIDQSAQKIVEAAKRTDVKVSGPIPLPTEKEVITILRA VHKYKDSR-EQFEQRTHKRLIDIINPNAKTLEALKKLNLPAGVDIEIKLRKTIVGIVVSDKMDKSIVVEVKTLVKDPKYG KQLRKTTKFKAHDEE--NIAGIGDKVKIMETRPLSKTKNWRLVEIIEKA------------------------------- -MSRSL-KKGPFCDE-HLMKKVEELNK---NDEKK----IIKTWSRRSTIFPNFVGHTIAVHDGRKHVPVYITD-DMVGH KLGEFVPTRTYKGHI------K--NEK----TSK-----VRN >FIRM_Geobacillus_kaustophilus_HTA426 Concatenation of 2 sequences MAIKKYKPTSNGRRGMTVLDFSE-ITTD------------QP-EKSLLAPLKKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--DK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYIIAPKNLKVGMEIMSGP-D-AD-IKIGNALPLE NIPVGTLVHNIELKPGRGGQLVRAAGTSAQVLGK--EGKYVIVRLASGEVRMILGKCRATVGEVGNEQHELVNIGKAGRA -RWL-----GIR-P-TVRGSVMNPVDHPHGGGEGKA-P--IGRKSPMTP---WGKPTLGYKTR-KKKNKSD-K-FIIRRR --------------------------------MTK---G-ILGRKIGMTQIFA-ENGD---------LIPVTVIHATPNV VLQKK----TIE----N--DGY--EAIQLGF-------ED--IANK----------PQIGHAK----------------- ---AN-TAPKRFIREIRG--------ANIDEY-----EV---GQ-EVKV--D-I-FSEGEIVDVTGISKGKGFQGAIKRH GQSR-GPMAHGS-RYHRR-PGSMGS--IAPN-RVFKTKNLPGRMGGERVTIQNLKIVKVDPERN---------------- ----------LLLIKGN-VPGPRKGLVIVK-MPKVALYN-QNGQTV-GEIELNDAVF----GI-EP-NKHVLFEAVIMQR ASMRQGTHKTKNRAE--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- RGGGTVFGPV-P-RSYSYKLPKKVRRLAIKSALSSKVLEN----------------D-IVVLDQL----SLE-A------ --PKTKLIV--TDELN--E---NVYLSARNIPGVK-V---------------VAANGINVLDVLNHDK----LVITKAAV EKVENRLKEKYLNEV----VPALMSKFNYKSIMQVPKIEKIVINMGVG-DAVQNPKALDSAVEELTLIAGQRPVVTRAKK SIAGFRLRQGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFRGVSK-KSFDGRGNYTLGIKEQLIFPEID-----YDKV NKVRGMDIVIVTT-----------------------ANTDEEARELLALLGMPFMSRVG-K--KPIEIPAGVTVT-V--- -N-G--N-TVTVKGPKGELTRTF--HP-D--MTITVEG-NV--ITV---TR-P--SDEKHHR-ALHGTTRSLLANMVEGV SKGYEKALELVGVGY--RASKQG-KK--LVLS--VGYSHPVEIEP-E-E-GLEIEVP--S-QTKIIVKG-ADKQRVGELA ANIRAVR------PPEPY---KGKGIRYEGELVRLKEGK----------MIQQESRLKVADNSGAREVLVIKVLG-SGRR Y--ANIGDVVVATVKDATPG-G-------VVKKGQVVKAVVVRTKRGVRRPDGSYIRFDENACVIIR-DDKS-PRGTRIF GPVARELR-DKDFMKIISLAPEVIMK-L--HELQPAPGS-RKKAVRVG-RGIGSGN-GKTSGRGQKGQNARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLEKLVTPELLLET-GVISVK---------ILG--KGQ-I-E-K-K-LTV- KAHKFSASAKEAIEAAGGKT-R---EHR--GRM---KGRA-KGGTEVHFG----------EFGLQAL--ESAWITNRQIE AARRAMTRYM------RRGGKVWIRIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVMFEV--GG-- VSEEVAREALRLASHKLPIKCKF-VRNAVRKKRHARIRKKI---FGTAERPRLSVFRSNKHIYAQIIDD---T--KSSTI VSASTL-DKEF---GL----DST-NNIEAAKKVGELVAKR--ALEKG-IKKVVFDRGGYLYH--GRVKALADAAREAGLE F--------------------------------------------------------------MQ-AKAVARTVRIAPRK ARLVIDLIRGKEVGEAFAILRHT---------------------------------PKAASPIIEKVLKSAVAN----A- EHNY-DMDVNNLVITQAYVDEGPTLKRFRPRAMGRASAINKRTSHITIVVSE-MHVKKGDKVQVISGK------DK-GKQ GVILAAFPKKN--RVI--VEGVNIVKKHAK----PS--QA-NPQ-GGIIEKEAPIHVSKVM-PLDPKT-------GE--P --TRIGYKI----V--------DGKVR---YAKKSG---EIL--MGQKVNPIGLRIG--II-RDWESRWYA------E-K D--YADLLHEDLKIREYI--SKRLQ-----DAAVSRVEIERAA-N-RVNVTIHTAKPGMVIGKGGSEVEALRKALAQLVH INIVEIKK---PDLDARLVAENIARQLENRVSFRRAQKQAIQRAMRA-GAKGIKTMVSGRLGGADIARSEHYSEGTVPL- -HTLRADIDYGTAEADTTYGKIGVKVWIY--MTDPIADMLTRIRNANMVRHEKLEV-PASKIKREIAEILKREGFIRDYE YIE----D---N----KQGILRIFLKYG---PNN-------E---RVITGLKRISKPGLRVYVKAHEVPRVLNGLGIAIL STSQGILTDKEARQKGTGGEVIAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGAKVSGPIPLPTERTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIINPTPQTVDSLMRLDLPSGVDIEIKLRKVYVGRVVSDKMDKTITVLVETYKKHPLYG KRVKYSKKYKAHDEH--NIAKVGDIVKIMETRPLSATKRFRLVEVIEKA------------------------------- -MGRSL-KKGPFCDE-HLMKKIEKLNA---TGQKQ----VIKTWSRRSTIFPQFVGHTIAVYDGRKHVPVYITE-DMVGH KLGEFAPTRTFRGHA------G--DDK----KTK------R- >FIRM_Geobacillus_thermodenitrificans_NG80-2 Concatenation of 2 sequences MAIKKYKPTSNGRRGMTVLDFSE-ITTD------------QP-EKSLLAPLKKKAGRNNQGKITVRH-QGGGHKRQ---- YRIIDFK-R--DK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYILAPKNLKVGMEIMSGP-N-AD-IKVGNALPLE NIPVGTLVHNIELKPGRGGQLVRAAGTSAQVLGK--EGKYVIIRLASGEVRMILGKCRATVGEVGNEQHELVNIGKAGRA -RWL-----GIR-P-TVRGSVMNPVDHPHGGGEGKA-P--IGRKSPMTP---WGKPTLGYKTR-KKKNKSD-K-FIIRRR --------------------------------MTK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVIEATPNV VLQKK----TIE----N--DGY--EAIQLGF-------ED--LANK----------PQIGHAK----------------- ---AN-TAPKRFIREIRG--------ANVNEY-----EV---GQ-EVKV--D-I-FSEGDIVDVTGISKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGA--IAPN-RVFKTKNLPGRMGGERVTIQNLKIVKVDPERN---------------- ----------LLLIKGN-VPGPRKGLVIVK-MPKVALYN-QNGQTI-GEIELNDAVF----GI-EP-NKHVLFEAVIMQR ASMRQGTHKTKNRAE--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPV-P-RSYSYKLPKKVRRLAIKSALSSKVLEN----------------D-IVVLDQL----SLE-A------ --PKTKLIV--TDELN--E---NVYLSARNIPGVK-V---------------VAANGINVLDVLSHDK----LVITKAAV EKVENRLKEKYTKEV----VPALMSKFNYKSIMQVPKIEKIVINMGVG-DAVQNPKALDSAVEELTLIAGQRPVVTRAKK SIAGFRLRQGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFRGVSK-KAFDGRGNYTLGIKEQLIFPEID-----YDKV NKVRGMDIVIVTT-----------------------ANTDEEARELLTLLGMPFMSRVG-K--KPIEIPAGVTVT-V--- -N-G--N-TVTVKGPKGELTRTF--HP-D--ITINVED-NV--ITV---TR-P--SDEKQHR-ALHGTTRSLLANMVEGV SKGYEKALELVGVGY--RASKQG-KK--LVLS--VGYSHPVEIEP-E-E-GLEIEVP--A-QTKVIVKG-ADKQRVGELA ANIRAVR------PPEPY---KGKGIRYEGEVVRLKEGK----------MIQQESRLKVADNSGAREVLVIKVLG-SGRR Y--ANIGDVVVATVKDATPG-G-------VVKKGQVVKAVVVRTKRGVRRSDGSYIRFDENACVIIR-DDKS-PRGTRIF GPVARELR-DKDFMKIISLAPEVIMK-L--HELQPAPGS-RKKAVRVG-RGIGSGN-GKTAGRGHKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLDRLVTPELLLEK-GVISVK---------ILG--KGQ-I-E-K-K-LTV- KAHKFSASAKEAIEAAGGKT-R---EHR--GRM---KGRA-KGGTEVHFG----------EFGLQAL--ESAWITNRQIE AARRAMTRYM------KRGGKVWIRIFPSKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKVMFEV--AG-- VSEEVAREALRLASHKLPIKCKF-VRNAVRKKRHARIRKKI---FGTAERPRLSVFRSNKHIYAQIIDD---V--KSATI VSASTL-DKEF---SL----DST-NNIDAAKKVGELVAKR--ALEKG-IKQVVFDRGGYLYH--GRVKALADAAREAGLE F--------------------------------------------------------------MQ-AKAVARTVRIAPRK ARLVIDLIRGKKVGEAFAILRHT---------------------------------PKAASPIIEKVLKSAVAN----A- EHNY-DMDINNLVVSQAYVNEGPTLKRFRPRARGQASAINKRTSHITIVVSE---------------------------- -------------------------------------------------------------------------------- --------------------------------------------MGQKVNPIGLRIG--II-RDWESRWYA------E-K D--YADLLHEDLKVREYI--NKRLQ-----DAAVSRVEIERAA-N-RVNVTIHTAKPGMVIGKGGSEVEALRKALAQLVH INIVEIKK---PDLDAKLVAENIARQLENRVSFRRAQKQAIQRAMRA-GAKGIKTMVSGRLGGADIARSEHYSEGTVPL- -HTLRADIDYATAEADTTYGKIGVKVWIYMVMTDPIADMLTRIRNANMVRHEKLEV-PASKIKREIAEILKREGFIRDVE YIE----D---N----KQGILRIFLKYG---PNN-------E---RVITGLKRISKPGLRVYVKAHEVPRVLNGLGIAIL STSQGILTDKEARQKGTGGEVIAYVWMAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGAKVSGPIPLPTERTVYTILRA VHKYKDSR-EQFEMRTHKRLIDIINPTPQTVDSLMRLDLPSGVDIEIKLRKVYVGRVVSDKMDKTITVLVETYKKHPLYG KRVKYSKKYKAHDEH--NIAKVGDIVKIMETRPLSATKRFRLVEVVEKA------------------------------- -MGRSL-KKGPFCDE-HLMKKIEKLNE---TGQKQ----VIKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYITE-DMVGH KLGEFAPTRTFRGHA------G--DDK----KTK------R- >FIRM_Halothermothrix_orenii_H_168 Concatenation of 2 sequences MAIKKFKPTTPSRRFMTVSAFDE-ITRR------------EP-EKSLLAPLKKTGGRNSYGRVTVRH-RGGGHKRR---- YRIIDFK-R--DK-DGVPARVASIEYDPNRSARIALLHYV-DGEKRYILAPNKLQVGDTVKSGE-D-AE-IKPGNALKLK NIPVGTIIHNIELKPGKGGQLARAAGTMAQILAK--EGKYAHIKLPSGEVRLISLECKATIGQVGNIDHENISIGKAGRK -RWL-----GKR-P-HVRGVAMNPVDHPHGGGEGRT-S--TGRH-PVTP---WGKRTLGKKTR-KR-KASD-K-YIIRSR --------------------------------MAK---G-IIGKKLGMTQIFD-DDGN---------VIPVTVVQAGPCV VIQKK----VEE----R--DGY--NALQVGF-------ED--VVNK----------PLKGHFR----------------- ---AG-VKPKKHVKEFMD---------FPEDL-----NE---GD-EITV--D-I-FEEGELVDVTGISKGKGFAGTIKRW NFSR-GPMSHGS-RFHRA-PGSIGA--VDAS-RVFKGQKLPGRMGHDRVTIQNLEVVRVDSEKN---------------- ----------LLLIKGS-VPGPNKGILTIR-MPQVAKYD-TTGNRV-GDIDLADNVF----NE-EV-NEHVVHQVVTAQL ATMRRGTASTKTRGE--------VS-GGGRKPW---------RQKGTGRAR--------HGS---IR-SP----LW---- VGGGIVFGPR-P-RKHIKKVPKKVKKLALRSILSYKSQNE----------------E-LIILDEL----KFD-T------ --PKTKLII--LPDKD--A---NIYLSARNIPGVK-T---------------LVVDALNAFDLLNNDC----IVMSEEAV KRVESVLAEQYKEEI----VPKLMDKFDYENIMAVPRVEKVVVNVGMG-ELKEDPKLIDVVVNDIASITGQKPVITRAKK SVANFKIREGMPIGAKVTLRGETMYEFLYKLVNVTLPRIRDFRGVSP-KSFDGRGNYNIGIREHIVFPEIE-----IDKV DKVYGLEITIVTS-----------------------AETDEEAYELLKLMGMPFMSRIG-K--LPVDIPEKVDVS-V--- -N-D--N-LVTVKGPKGELTKEF--NNKK--VTVEVKD-GQ--VLV----R-RVHDKDKDAR-AFQGLTRSLIDSMVEGV TNGFEKKLEMVGVGY--NAKKKG-KD--LELE--VGYSHPVIIEA-E-D-GIEFDVE--K-NNKIVVRG-IDKQQVGEMA AKVRAVR------KPEPY---KGKGIRYEGEHIRRKEGK----------MIQAESRLRVADNTGARELLCIRVLG-SRKR Y--AGVGDIIVATVKEAIPD-G-------MVKKGEVVKAVVVRTKKETRRPDGSYIKFDENAAVLID-KANN-PRGTRIF GPVARELR-EKNFMKIISLAPEVLMK-L--HDLRPAKDA-KKKRKRVG-RGTGSGR-GFTSGRGSKGQNARSGGG-V--- -RPTF-E-GGQTPLFRKLPK-KG--FNNVNVYQLVTPEKLLEK-GIIDVK---------ILG--NGE-L-D-K-A-LTV- KAHAFTKSAREKIEAAGGKA-K---QHR--GRM---TGKA-KRGNRITFG----------EYGLQAL--EPAWITNRQIE AARVAITRSL------KRGGKVWIKIFPDKPVTAKPAETRMGGGK---------GAPEKWVAVVKP-GRIMFEV--AG-- VSEELAREAIRLASHKLPIKTRF-VKRLARKRRHLRIRNKI---FGTPERPRMSVFRSKKNIYVQVIDD---I--SGHTL VSASSL-DPAI-RDEI----DNG-GNVEAAKKVGELVAER--ALEKG-IKKVVFDRGGNRYH--GRIKALAEAARAKGLK F--------------------------------------------------------------ME-ARAVAKYVRVSPRK ARQVIDLIRGKEIGEALGILKHT---------------------------------PKKASSIIEKVLNSAIAN----A- ENNH-DMMVEDLYVSKAYVDEGPTMKRYRARAMGQAGLIRKRTSHITIVVSE-MRVKKGDLVEVIAGK------DR-GKR GKVLRVIPRED--RVI--VEGINIVHRHMR----PT--PD-MPQ-GGIVKNEAPIHISNVM-LVCPNC-------DE--K --TRIGATY---LE--------DGKVR---KCKKCD---EVV--MGQKVHPHGLRVG--VI-KDWDAKWYA------DKN N--YADLLQEDLKIRNHV--KNKMY-----DAGISRIVIERVA-N-RLKLDVYTARPGMVIGRGGSEVDALRKDIEQMVQ INVVEVED---PELDAQLVAENIAAQLERRISFRRAMKQAMNRAMRM-GAEGFKVQSSGRLGGAEMARTEGYSDGRVPL- -HTLRADIDYGFAEAYTTYGKIGVKVWINMNITDPIADMLTRIRNANDTNKDVVNI-PASNMKISIARILKEEGYIKDYK VIE----K---K----PQNALRIYLKYS---KNG-------E---KVISGLKRISKPGLRVYVKKDEVPKVLGGLGIAVL STSRGILTDKQARQEGIGGEVLCYVWAKHEKIRIRLKAYEHELLDQSAQKIVATAKRTGAEVSGPIPLPTEKEVYTVLRS PHVHKDSR-EQFEMRTHKRLIDIVDPTSKTVDALMRLDLPAGVNIEIKLRKERVGVVVSDKMDKTVTVAVERRTQHHLYK KVMKKTKKFKAHDEE--NKCGVGDKVRIMETRPLSKNKRWRVVEIIEKA------------------------------- -MGRSL-KKGPYVDK-KLLNKIKEMNE---SGKKK----VIKTWSRDSTIFPEMVGHTIAVHDGQKHVPVYITE-DMVGH KLGEFAPTRKFRGHG------A-HTER----STA------LK >FIRM_Heliobacterium_modesticaldum_Ice1 Concatenation of 2 sequences MAVKKFKPTSPGIRQMTVASFDE-ITKT------------KP-EKSLLEPLKKKAGRNNQGKLTVRH-QGGGHKRM---- YRVIDFK-R--IK-DGIPAKVASIEYDPNRTSRIALLHYA-DGEKRYIIAPNGLNVGDTVVSGP-D-AD-IKTGNCLPLK NIPVGTLIHCIEMRPGKGGQLVRSAGAAAQLMAK--EGEHATLRLPSGEMRKVLAECRATIGQMGNLEHENITIGKAGRK -RWL-----GIR-P-TVRGVVMNPVDHPHGGGEGRS-P--IGRKAPVTP---WGKVAIGGKTR-RKKA-SD-K-LIIKRR --------------------------------AKK---G-LLGRKIGMTQVFA-DNGV---------AVPVTVVQAGPCV VVQKK----TVE----K--DGY--EAVQIGF-------GD--VLNK----------PKRGHLN----------------- ---AG-VRLVRVLREIKV--------DSMDEY-----KV---GQ-ELKA--D-V-FSAGEYVDVVGTSKGKGFAGGIKRH NFKR-GPMKHGS-KYHRR-PGSAGA--KGPA-RIFKGRKMPGRMGNERVTVQKLQVVRVDAERN---------------- ----------LLLIKGA-VPGPKRGLLLIK-MPKVALYN-TEGAQV-GEIELNDAIF----GI-EP-NEAVMHQAVVTQL AAWRRGTHKVKSRGE--------VS-GGGKKPW---------RQKGTGRAR--------AGT---SR-SP----LW---- RGGAIIFGPQ-P-RSYKIAMPKKVRRLALKSALSDKVRSG----------------N-LIVVDAL----EMD-A------ --PKTKLLV--TADID--E---TVFKSARNIPGVS-P---------------VEAVGINVYDILNHDK----LVITKNAV AKVEARLKEKIQTDV----NAAMMQRFGYKNVMQIPRLEKVVVNMGLG-EAIQNPKGLDAAVGDLTRITGQKPVITTAKK SIAGFKLREGMKIGCKVTLRGDKMYDFVDKLVNLSLPRVRDFRGVSP-KSFDGRGNYTLGLKEQLIFPEIE-----YDKI DRLRGMDVTFVTT-----------------------AKTDEEARELLRLIGMPFMSRIG-K--KPVAIPAGVNVT-I--- -E-G--N-VVTVKGPKGQLSREL--HK-D--IIVTVEG-NT--VQV---TR-P--SDDKFHR-SLHGLSRTLVANMVDGV SVGFSKSLELVGVGY--RAAKQG-KK--LVLT--VGYSHPVEIE--PGE-GLEVEVP--A-PTKIIVKG-IDKEKVGALA ANIRAVR------EPEPY---KGKGIKYETEVIRRKVGK----------MIQQETRLRVGDNTGAKELLCIRVLG-SYRR Y--ASVGDIIVASVKEATPG-G-------VVKKGDVVKAVVVRTRKPIKRPDGSYIRFSENAAVIIN-EQKN-PKGTRIF GPVARELR-DRDFMKIISLAPEVLMQ-L--HELKPAPGS-RQKPTRKG-QGIGSGL-GKTAGRGHKGQKARSGGG-V--- -RPGF-E-GGQQPLQRRLPK-RG--FTNINVGDLVTPELLLER-KMIKVK---------LLA--DGN-I-E-K-A-LTV- KLHGVSEAAAEKIKAAGGQV-R---VQR--GRL---KGKS-KGGNSVAFG----------EYGLQAL--EAAWITSRQIE AARIAMTRYI------KRGGKVWIKIFPDKPITAKPAETRMGSGK---------GSPEYWVAVVKP-GRIMFEL--AG-- VPEDTAKEAMRLAMHKLPIKCKF-VRDAARQKKHMRIRKRV---KGTEERPRLCVFRSLNHIYAQVVND---V--TGRTL VAASSL-DGEF-KAAN----VSG-GNIEGAKKVGELIAKK--ALEKG-IDKVVFDRGGYIYH--GRIAALAEAAREAGLQ F-------------------------------------------------------------AKT-AQAVAKYVRTSPRK VRQVIDLIRGKSVADAFAILKFT---------------------------------PVKSAADVAKVLKSAVAN----A- EHNY-EMNTADLYVQTCFVDQGPSMKRISPRAQGRADVIKKRMSHITVIVAEKVHVRKGDLVQVITGK------DA-GKK GKIIEVIPAKN--RVV--VEKVNIVKRHSK----PS--KT-NPQ-GGIIEKEAPIDASNVM-IFCPKC-------DR--P --VRSGHKF---LE--------NGKAR---ICRKCG---DVL--MGQKVNPKGLRIG--II-KDWDARWFA------G-K N--YAELLHEDLKIRKFV--KSKLY-----AAGIPRIEIERAA-N-RVKVTIHTAKPGIVIGRGGAEVENLRKELEKMVN INIAEVKK---PELDAQLVAENVAAQLEKRTSFRRAMKQSVGRTMRL-GAEGIKIMVSGRLGGAEIARTEWYNEGKVPL- -HTLRADIDYGFAEARTTYGIIGVKVWIYMVMTDPIADFLTRIRNANMVYHDKVEV-PASKVKRAIAEIFKNEGYVKDVE YVE----D---N----KQGLLRIYLKFG---PNR-------E---KVITGVKRISKPGLRVYARKEEIPKVLGGLGVAVL STSQGIMSDKAARKAGLGGEVLCYIWMGKQKIRIRLKAFDHRILDQSSEKIVETAKRTGAAVSGPIPLPTEKSIYTILRS PHVNKDSR-EQFEMRTHKRLIDILEPNPKTVDALMRLDLPAGVDIEIKLRKTRIGKVTSNKMEKTVVVAVESRIQHPLYG RTVKKTKKFKAHDEE--NACQIGDVVEIMETRPLSKEKRWRVVRIVEKA------------------------------- -MSRSL-KKGPYVEA-SLLKKVEELNQ---KNEKR----VIKTWSRRSTIFPQFVGHTFAVHDGRKHIPVYVTE-DMVGH KLGEFAPTRTFKGHA------G--SEK----SSR------LR >FIRM_Lactobacillus_acidophilus_NCFM Concatenation of 2 sequences MAIKIYKPTTNGRRHMTSSDFAE-ITKT------------KP-EKTLLESQSHTAGRNSYGRITVRH-RGGGHKQK---- YRIIDFK-R--NK-DNVKAVVNAIEYDPNRTANIALLHYT-DGIKAYILAPKGLKVGDIVESGD-S-VD-IKPGNALALK NIPTGTSIHNIELKPGKGGQLVRSAGASAQVLGF--DGNYTLVRLQSGEVRKILSSCRATIGVVGNEQHSLIQLGKAGRK -RWL-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPQPMTP---WGKKARGIKTR-DVKKASE-K-LIIRHR --------------------------------MTK---G-ILGRKVGMTQIFT-KDGI---------LVPVTVVEATPNV VMQVK----TVE----S--DGY--EAVQLGY-------QD--KSNK----------PEKGHAK----------------- ---AK-TSPKRFIREIRG--------VELKDY-----EV---GS-EVTV--D-T-FKEGDVVNVTGTSRGHGYQGNIKRW GQSR-GPETHGS-RYHRI-PGSMG---SIIN-RVPKGKRLPGHMGVKKVTIENLVIEKVVADKN---------------- ----------VLMIKGN-VPGAKNSLIVVK-MANLKVMD-QNGKDS-GEVTLNDKVF----GI-EP-NDNVVFEAIIRQR AGKRQGTSKVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- RGGGTVFGPT-P-RSYAYTMPRKQRRLAIKSVLSQKLIDN----------------D-LIVLDKL----TMS-A------ --PKTKLIV--S--DD--N---NVQLSARNLAKVK-V---------------VPVNGLNVEDAVNYGK----LILTQDAV KKIESYLAEEYKETV----APALKEKFNYTSSMQIPKIDKIVLNMGVG-DAVSNAKNLDEAVEELTLISGQKPLITKAKK SIANFRLREGMSIGAKVTLRGDRMYDFLYKLINVSLPRVRDFRGVST-RSFDGRGNYTLGIKEQLIFPEID-----FDKV NRTRGLDIVIVTT-----------------------ADTDEEARELLSQFGMPFMSRIG-L--KTIEVPDSVTVT-K--- -E-G--D-NITVKGPKGELTRYF--DP-K--ITFEQND-GE--INF------S--RSSESDK-ALHGTERANLASMIEGV LNGYKKTLKLIGVGY--RAQAQG-NK--ITLN--VGYSHPVVLTA-P-E-GVSVKAT--S-ATDVEVEG-VSKQDVGQFA AEIRAVR------PPEPY---KGKGIRYVDEYVRRKEGK----------MIQNESRLKVADNSGARELLVIRVLG-SKRK T--GNIGDIVVCTVKQATPG-G-------VVKKGDVVKAVIVRTKSGARREDGSYIKFDENAGVIIN-ADKS-PRGTRIF GPVARELR-ENDFMKIVSLAPEVLMK-L--HELHSAEGS-RRNRKRVG-RGTSSGY-GKTSGRGQKGQLARQGGH-T--- -RLGF-E-GGQMPLFRTMPK-RG--FKNVNLDDLVTVATLKEN-GLVKVK---------LLG--NGE-L-K-V-K-LTV- KVNKVSAAAKEAVEAAGGTVMR---EFR--GKM---RGAA-KGGKYIAFG----------EYGLEAL--ESHWITNRQIE AARVAMTRYM------KRGGKVWIRIFPQKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-EKILFEI--GG-- VSEEVAREALRLASTKLPIKTKF-VKNKLRLKRHRRIRGKI---SGTAERPRLSIFRSNKNIYAQLIDD---V--AGVTL ASASTL-DENV---------SDA-TKLEQAAAVGKAIAEA--AKAKN-ISTVVFDRSGYLYH--GRIQALADAARENGLD F-------------------------------------------------------------ISS-AKAEARTVRIAPRK ARLVIDLIRGKSVAEALAILEFT---------------------------------PRAASPIVEKVLRSAIAN----A- EHNY-DLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSE-MFVKTGDKVKVIAGK------DK-GKE GTVLSVNVKKN--RVV--VKGVNKIKKHQK----PS--QT-NAN-GGVVESEGSIHASNVK-VISKKE-------DK--- --------------------------------------------MGQKINPNGFRLG--VI-RDWESKWYA------D-K G--YKETLKEDLQIRKFI--SEKLK-----DASVSTVEIERAA-N-RINISIHTAKPGMVIGKGGSEVEALRKQLNALVH INIVEIKK---PDLDAELVADSIARQLEARIAFRRAMRQATQRAMLA-GAKGIKVQTSGRLNGADMARREWHTEGRVPL- -QTLRADIDYAWVNAFTTYGEIGVQVWINMVMTDPIADYLTRIRNANMAKHDSVEI-PASNIKKSISEILKREGFIRDYE VAD----D---N----KQGVIKVFLKYG---PNG-------E---RVISGLKRISKPGLRNYVSAEDLPKVLNGLGIAIV STSAGVITDKEARQKNVGGEVVAYVWMASQTIRIRLKSYEHGILDESAAKIVATAKRTGAEISGPVPLPTERTLFTVLRS PHKNKDSR-EQFEMRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKLRHVYQGRVVSDKMDKTITVVVDTYKNHPVYN KRFRYSKKYYAQDEN--NEAKVGDTVRIMETRPLSRKKRFRLVKIVKKS------------------------------- ----------------MMHKQMQIRSK------------LLKLGHVRSTIFPSFVGLTIAVYDGRKHVPVYITE-DMVGH KLGEFVPTRTFHGHK-------STDDK----ATS------QS >FIRM_Lactobacillus_brevis_ATCC_367 Concatenation of 2 sequences MAIKKYKPTSNGRRNMTSLVYKDVITKT------------TP-EKSLLDSQSHSAGRNNAGKMTVRH-RGGGNKRQ---- YRIIDFK-R--IK-DDVPATVKAIEYDPNRTANIALLVYA-DGVKSYIIAPKGLKVGDKVQSGP-E-AD-IKTGNALPLK NIPFGTVIHNIELKPGKGGQLVRSAGTSAQLLGKANDEKYVLVRLSSGEVRMVLSVNRATIGAVGNEEHELVNVGKAGRT -RWA-----GQR-P-HVRGSVMNPNDHPHGGGEGKA-P--VGLPSPLSP---WGKKTVGKKTR-SKKNKTE-K-FIVRHR --------------------------------TTK---G-ILGKKVGMTQVFT-DAGE---------LIPVTVVEATPNV VLQVK----TME----N--DGY--NAIQLGY-------QD--KSNK----------PEQGHVK----------------- ---AN-TTPKRFIREFTD--------VELGDY-----KV---AD-EVKV--D-T-FQAGDIVDVTGVTKGHGYQGNIHKD GQSR-GPMAHGS-RYHRR-PGSLG---AIIN-RVFPGMKLPGRMGNKQVTIQNLVIVKADVENN---------------- ----------VLLIKGN-VPGANKSLVTVK-MTSVALYK-QDGSQN-GNVELNADIF----GV-EP-NENVVFDTILMQR ASLRQGTHAVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- VGGGVVFGPT-P-RSYSYRLPKKVSRLALKSVLSQKVLDE----------------S-FVVVDGL----AFD-A------ --PKTKLVV--LEDDN--V---TAALAARNLTNVK-V---------------IPAKGLNVLDIADADK----LVITQPAL SQVEARLKEKYVSEI----TPALVEKFSYSSVMQTPKIEKIVLNMGVG-DAVSNAKNLDEAVEELGLISGQKPLVTKAKK SIATFRLREGMSIGAKVTLRGDRMYEFLDKLINVSLPRVRDFHGVSS-RAFDGRGNYTLGVREQLIFPEIN-----FDNV NRVRGLDIVIVTT-----------------------ANTDEESRELLTQFGMPFMSRIG-Y--KTVNVPAGVEVK-R--- -D-G--D-QVTVKGPKGELTRTF--SS-V--ISMKISD-GA--VDF---DR-P--DNNNKTR-ALHGTQRANLNNMVEGV VSGFAKTLKLVGVGY--RVQAKG-KT--LILS--VGYSNPVEMAI-P-E-TLEVKVP--D-NTTINISG-ISKQEVGDFA AEVRAVR------SPEPY---KGKGIRYENEYVRIREGK----------MIQQESRLKVADNSGAREILTIKVLG-SKRR Y--AGIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKSRVRRNDGSYISFDENAAVLIK-DDKS-PQGTRIF GPVARELR-DNDYMKIISLAPEVLMK-L--NELKPAEGS-RKVRNRVG-RGDSSGN-GKTAGRGQKGQKARSKT------ -RLGF-E-GGQMPLYRRIPK-RG--FTNVNLSALVTPAALVEA-GIVKIK---------ILG--NGE-L-S-K-K-LTV- KAAKFSKSAAEAIEAAGGKT-R---VHR--GKL---RGEA-KGGKSVAFG----------DYGLQAL--DSHWISNRQIE AARVAITRYM------KRGGKVWIKIFPHKSYTAKGVGVRMGNGK---------GTPDGWVAPVKR-GKVMFEV--GG-- VSEEVAREALRLAAMKLPVRTKV-LKNKTRQKRHIRVRNKI---SGTAERPRLNVFRSNKNIYAQVIDD---V--AGVTL VSASTL-DSEV---------AGD-NKTDQAKGVGELIAKR--AIEKK-ITNVVFDRGGYLYH--GRVQALAEAAREAGLK F-------------------------------------------------------------VTS-AQATAKTVRIAARK VRLVIDLIRGKSVAEALAILQFT---------------------------------PRGASPVVAKVLNSAVAN----A- ENNF-DLDRQDLVVSEAYVNEGPTLKRFRPRAKGSASPINKRTSHITVVVSE-MLIKTGDKVRVIAGK------DK-GKE GTVSKVLNAKN--RVI--VQGVNMIKKHQK----AS--QT-NPQ-GGIIDIEAPIHASNVM-LIDPSN-------NE--P --TRLGVRV----E--------DGKVR---FAKKSG---ETI--MGQKVNPTGLRVG--II-RDWEAKWYA------E-K D--FAAYLKEDLQIRKFI--EKRLV-----DASVSTVEIERAA-N-RVNISIHTAKPGMVIGKGGSEVENLRKELNDLVH INIVEIKK---PDLDAKLVGENIARQLEGRVAFRRAMRGTMQRTMRS-GAKGIKTQVAGRLNGADMSRVESYAEGTVPL- -HTLRADIDYAWVEAHTTYGSLGVKTWIYMSMTDPIADFLTRIRNANMVRHESLEV-PASKIKRDIAEILKREGFIRNVE YID----D---D----KQGIIRVFLKYG---KDN-------Q---RVISGLKRISKPGLRSYVKADAVPKVLNGLGIAII STSEGVVTDKEARAKKIGGEVLAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGAGISGPIPLPTERTIYTVLRS PHKFKDSR-EQFEMRTHKRLIDIVNPTPKTVDSLMKLDLPSGVDIEIKLRKVYRGRVVSDKMDKTITVVVETTKTDARYG KRVKYSKKYKAHDEN--GEAHTGDIVEIMETRPLSATKRFRLVDIVEKA------------------------------- -MGRSL-KKGPFADA-HLLKKIDAQKD---SEKKT----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYVQE-DMVGH KLGEFVPTRTFRGHG------G--DDK----KTR-------- >FIRM_Lactobacillus_casei_ATCC_334 Concatenation of 2 sequences MAIIKYKPTSNGRRNMSGSDFAE-ITKT------------KP-EKTLLVSQSHTAGRNAHGHITVRH-RGGGHKQF---- YRVIDFK-R--NK-DGMAATVKAIEYDPNRTANIALLHYE-DGVKSYILAPKGLKVGDKVYSGE-D-VD-IKVGNSLQLK NIPAGTTIHNIELKPGKGAQLARSAGVSAQLLGKDND-KYVTVKLASGEVRLILAENRATIGAVGNEQHELISIGKAGRK -RWL-----GFR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGHPSPMSP---WGKKTLGKKTR-DHKAKSE-K-FIVRHR --------------------------------ARK---G-ILGKKVGMTQVFT-DNGE---------LVPVTVVDVTPNV VMQVK----TVE----S--DGY--EAVQLGY-------GD--MTNK----------PSVGHAK----------------- ---AD-TTPKRFVREIRD--------VALSDY-----EI---GS-EVKA--D-E-FAAGDIVDVTGTSKGHGYQGNIKKD GQSR-GPMAHGS-RYHRR-PGSLG---AIIN-KVFKGKKLPGRMGNHTRTMQNLQVVAADTEHN---------------- ----------VLLIKGN-VPGANKSFVTIR-MANVTLYK-QDGSEN-GKVELNDAIW----AV-EP-NENVVFDAVVMQR DSLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYAYKLPKKVRRLAIKSVLSQKVLDS----------------D-LVVVDGL----NFD-A------ --PKTKLVV--LEDGN--E---VAAKAARNLPNVK-V---------------VPAEGINVLDVVDYKK----LILTQSAL QKIENRLEERYSKEI----APALVSKFNYKSTMQAPKIEKIVLNMGVG-DATQNAKLLDEAVDELTLISGQHPLITKAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLINVSLPRVRDFHGISP-KSFDGRGNYTLGVKEQLIFPEID-----YDKV NRVRGLDVVIVTT-----------------------ANTDEEALELLTQVGMPFMSRIG-Y--KVIKVPAGVTIT-K--- -D-G--D-NITVKGPKGELTRHF--AP-E--IEMHQEG-DE--INF---TR-P--DDS--YK-AVHGTMRANLNNMVVGV TEGYKKEMKLVGVGY--RAQKQG-EK--LVLN--VGYSHPVEMTA-P-K-GVTVEVP--S-TTQIIISG-ISKQVVGQFA AVVRSVR------APEPY---KGKGIRYVDEHVRRKEGK----------MIQQESRLKVADNSGAREILVIKVLG-SYRK T--GNIGDVVVATVKQATPG-G-------VVKKADVVKAVIVRTKSGARRADGSYIKFDENAAVIIN-ADKS-PRGTRIF GPVARELR-DGDFMKIVSLAPEVLMQ-L--HELKPSVGS-RHSRKRLG-RGTSSGQ-GKTAGKGTKGQLARQGGK-T--- -RLGF-E-GGQMPLFRRMPK-RG--FNNVNLSDLVTPAALIDA-GIVKVK---------LLA--DGK-L-E-K-K-LTI- KVAKASAAAKAAVEAAGGSI-R---EFR--GKM---RGAA-KGGRNVDFG----------EYGLEAL--ESHWITNRQIE AARVAMTRYM------KRGGKVWIRIFPHKSYTSKGVGVRMGNGK---------GAPTGWVAVVKR-EKIMFEV--GG-- VSEAVAKEALRLASNKLPIRTKI-VKNKTRQRRHARVRGKI---SGTSERPRLNIFRSNKNIYAQLIDD---V--AGVTL ASASTL-DKDI-KDPE--------NKTAASAQVGALIAKR--AVADG-HKVVVFDRGGYLYH--GRVAALAEAARENGLE F-------------------------------------------------------------ITS-ATATAKTVRIAARK ARLVIDLIRGRDVAEALAILEFT---------------------------------PRSGSPIIEKVLKSAIAN----A- EHNY-DLDAQNLYVSKAYVNEGPTLKRFRPRAKGSASPINKRTSHVTVVVSE-MKFKTGDKVRVMRGK------DA-GKE GQITKVLKDAD--KVV--VEGINMIKKHQK----PN--NA-NPQ-GGIIDKEAPIHVSNVM-LLDPDT-------NK--P --TRIGSEV----K--------DGKVR---IAKKSG---TAI--MGQKINPTGFRVG--VI-RDWDAKWYA------D-K D--FAAFLHEDIEIRNFI--NKKLQ-----DASVSRIEIERAA-K-RVNISIHTAKPGMVIGKGGSEVENLRKQLNKLVH INIVEIKK---PDLDAKLVGENIARQLEQRIAFRRAMRQAMQRTMRA-GAKGIKTQASGRLNGADIARREHYNEGLVPL- -HTLRADIDYAWEEAATTYGRIGIKTWINMVLTDPIADYLTRIRNANMVRHESLVV-PASKMKKDISEILKREGFIRDYE VID----D---D----KQGVIRIFLKYG---KNN-------E---RVISGLKRISKPGLRSYVKSDAVPKVLNGLGIAII STSEGVITDKEARAKNVGGEVLAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGATISGPIPLPTERTLYTVLRS PHKYKDSR-EQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVEVSTVKMHPVYG KRMKYSKKYYVHDED--NTAKTGDIVRIAETRPLSRNKRFRLLNIVEKA------------------------------- -MGRSL-KKGPFADA-HLLKKIEAQAD---NDKKT----VIRTWSRRSTIFPSFIGYTIAVYDGRKHVPVFVSE-DMVGH KLGEFVPTRTFRGHN------T--DDK----KTT------AR >FIRM_Lactobacillus_casei_casei_BL23 Concatenation of 2 sequences MAIIKYKPTSNGRRNMSGSDFAE-ITKT------------KP-EKTLLVSQSHTAGRNAHGHITVRH-RGGGHKQF---- YRVIDFK-R--NK-DGMAATVKAIEYDPNRTANIALLHYE-DGVKSYILAPKGLKVGDKVYSGE-D-VD-IKVGNSLQLK NIPAGTTIHNIELKPGKGAQLARSAGVSAQLLGK--DDKYVTVKLASGEVRLILAENRATIGAVGNEQHELISIGKAGRK -RWL-----GFR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGHPSPMSP---WGKKTLGKKTR-DHKAKSE-K-FIVRHR --------------------------------ARK---G-ILGKKVGMTQVFT-DNGE---------LVPVTVVDVTPNV VMQVK----TVE----S--DGY--EAVQLGY-------GD--MTNK----------PSVGHAK----------------- ---AD-TTPKRFVREIRD--------VALSDY-----EI---GS-EVKA--D-E-FAAGDIVDVTGTSKGHGYQGNIKKD GQSR-GPMAHGS-RYHRR-PGSLG---AIIN-KVFKGKKLPGRMGNHTRTMQNLQVVAADTEHN---------------- ----------VLLIKGN-VPGANKSFVTIR-MANVTLYK-QDGSEN-GKVELNDAIW----AV-EP-NENVVFDAVVMQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYAYKLPKKVRRLAIKSVLSQKVLDS----------------D-LVVVDGL----NFD-A------ --PKTKLVV--LEDGN--E---VAAKAARNLPNVK-V---------------VPAEGINVLDVVDYKK----LILTQSAL QKIENRLEERYSKEI----APALVSKFNYKSTMQAPKIEKIVLNMGVG-DATQNAKLLDEAVDELTLISGQHPLITKAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLINVSLPRVRDFHGISP-KSFDGRGNYTLGVKEQLIFPEID-----YDKV NRVRGLDVVIVTT-----------------------ANTDEEALELLTQVGMPFMSRIG-Y--KVIKVPAGVTIT-K--- -D-G--D-NITVKGPKGELTRHF--AP-E--IEMHQEG-DE--INF---TR-P--DDS--YK-AVHGTMRANLNNMVVGV TEGYKKEMKLVGVGY--RAQKQG-EK--LVLN--VGYSHPVEMTA-P-K-GVTVEVP--S-TTQIIISG-ISKQVVGQFA AVVRSVR------APEPY---KGKGIRYVDEHVRRKEGK----------MIQQESRLKVADNSGAREILVIKVLG-SYRK T--GNIGDVVVATVKQATPG-G-------VVKKADVVKAVIVRTKSGARRADGSYIKFDENAAVIIN-ADKS-PRGTRIF GPVARELR-DGDFMKIVSLAPEVLMQ-L--HELKPSVGS-RHSRKRLG-RGTSSGQ-GKTAGKGTKGQLARQGGK-T--- -RLGF-E-GGQMPLFRRMPK-RG--FNNVNLSDLVTPAALIDA-GIVKVK---------LLA--DGK-L-E-K-K-LTI- KVAKASAAAKAAVEAAGGSI-R---EFR--GKM---RGAA-KGGRNVDFG----------EYGLEAL--ESHWITNRQIE AARVAMTRYM------KRGGKVWIRIFPHKSYTSKGVGVRMGNGK---------GAPTGWVAVVKR-EKIMFEV--GG-- VSEAVAKEALRLASNKLPIRTKI-VKNKTRQRRHARVRGKI---SGTSERPRLNIFRSNKNIYAQLIDD---V--AGVTL ASASTL-DKDI-KDPE--------NKTAASAQVGALIAKR--AVADG-HKVVVFDRGGYLYH--GRVAALAEAARENGLE F-------------------------------------------------------------ITS-ATATAKTVRIAARK ARLVIDLIRGRDVAEALAILEFT---------------------------------PRSGSPIIEKVLKSAIAN----A- EHNY-DLDAQNLYVSKAYVNEGPTLKRFRPRAKGSASPINKRTSHVTVVVSE-MKFKTGDKVRVMRGK------DA-GKE GQITKVLKDAD--KVV--VEGINMIKKHQK----PN--NA-NPQ-GGIIDKEAPIHVSNVM-LLDPDT-------NK--P --TRIGSEV----K--------DGKVR---IAKKSG---TAI--MGQKINPTGFRVG--VI-RDWDAKWYA------D-K D--FAAFLHEDIEIRNFI--NKKLQ-----DASVSRIEIERAA-K-RVNISIHTAKPGMVIGKGGSEVENLRKQLNKLVH INIVEIKK---PDLDAKLVGENIARQLEQRIAFRRAMRQAMQRTMRA-GAKGIKTQASGRLNGADIARREHYNEGLVPL- -HTLRADIDYAWEEAATTYGRIGIKTWINMVLTDPIADYLTRIRNANMVRHESLVV-PASKMKKDISEILKREGFIRDYE VID----D---D----KQGVIRIFLKYG---KNN-------E---RVISGLKRISKPGLRSYVKSDAVPKVLNGLGIAII STSEGVITDKEARAKNVGGEVLAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGATISGPIPLPTERTLYTVLRS PHKYKDSR-EQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVEVSTVKMHPVYG KRMKYSKKYYVHDED--NTAKTGDIVRIAETRPLSRNKRFRLLNIVEKA------------------------------- -MGRSL-KKGPFADA-HLLKKIEAQAD---NDKKT----VIRTWSRRSTIFPSFIGYTIAVYDGRKHVPVFVSE-DMVGH KLGEFVPTRTFRGHN------T--DDK----KTT------AR >FIRM_Lactobacillus_delbrueckii_bulgaricus_ATCC_11842 Concatenation of 2 sequences MAIKVYKPTSNGRRNMTSSDFAE-ITKS------------KP-EKTLLASKSKTAGRNSYGHITVRH-RGGGHKQQ---- YRIIDFK-R--TK-DNVKAKIVAIEYDPNRSANIALLHYT-DGTKAYILAPKGLTVGSWVESGV-D-AD-IKVGNALPLK NIPTGTEVHNIELKPGKGGQIARSAGTSAQVLGV--DGKYTQVRLQSGEVREILSECRATIGAVGNEQHSLINIGKAGRS -RWM-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPQPMTP---WGKKSRGIKTR-DSKKASE-K-LIIRHR --------------------------------MTK---G-ILGRKVGMTQIFT-KDGV---------LVPVTVIEATPNV VMQVK----TVE----N--DGY--EAVQLGY-------QD--KSNK----------PEKGHAK----------------- ---AK-TSPKRFIRELRG--------VELSDY-----EV---GS-EVTV--E-T-FKEGDVVNVTGTSRGHGYQGNIKRH HQSR-GPETHGS-RYHRI-PGSMG---SIIN-RVPKGKKLPGHMGVKTVTIENLVVEKVVADKN---------------- ----------VLMIKGN-VPGAKNSLIVVK-MANFKLMD-QNGNNA-GEVTLNDNVF----SV-EP-NEAVVFDAIIRQR AGKRQGTSKVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- RGGGVVFGPT-P-RSYAYSMPRKQRRLAIKSVLSQKLLDQ----------------N-LVVLDKL----TMD-A------ --PKTRLVV--S--DD--K---NVQLSAKNLPKVK-V---------------VPVNGLNVEDAVNYDK----LVLTQDDV KKIENSFATKYNEEI----VPALTKKFNYTSSMQVPKIDKIVLNMGVG-DAVANAKNLDEAVEELTLISGQKPMITKAKK SIANFRLREGMSIGAKVTLRGDRMYDFLSKLINVSLPRVRDFRGVST-RSFDGRGNYTLGVKEQLIFPEID-----FDKV NRTRGLDIVIVTT-----------------------AQTDEEARELLTQFGMPFMSRIG-L--KVINVPESVTVT-K--- -N-G--N-EITVKGPKGELTREF--DP-R--IKFEQED-GV--IRF------S--RSNENDK-AIHGTMRANLANMIEGV VNGYKKELKLIGVGY--RAVAKN-NV--LTLN--VGYSHPVEMKA-P-E-GVTVTTS--S-ATDVTIEG-ISKQVVGQFA AEIRAVR------SPEPY---KGKGIRYADEVVRRKEGK----------MIQTETRLKVADNSGARELLVIRVMG-SKRK T--GNIGDIVVAAVKQATPG-G-------VVKKGDVVKAVIVRTKSGARREDGSYIKFDENAAVIIN-ADKS-PRGTRIF GPVARELR-EGDFMKIVSLAHEVLMK-L--NELHPSEGS-RHARKRVG-RGTSSGF-GKTSGRGQKGQHARSGGN-T--- -RLGF-E-GGQMPLFRTMPK-RG--FKNVNLADLVDFEALKAK-GLVKVK---------VLG--NGD-L-N-V-K-LTV- KVNKVSEAAKSAIEAAGGTVMR---EFR--GKM---RGAA-KGGKTVAFG----------EYGLEAL--ESHWITNRQIE AARVAMTRYM------KRGGKVWIRIFPQKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-EKIMFEI--GG-- VSEETAREAMRLAASKLPIKCKF-VKNKLRLKRHRRVRGKI---SGTAERPRLSVFRSNTNIYAQLIDD---V--AGVTL ASASTL-DKSV--------SKDA-TKVEQAQAVGKAIAEA--GKAKG-ITEVVFDRGGYIYH--GRVKALADAARENGLE F-------------------------------------------------------------ISS-ARAEARTVRIAPRK ARLVVDLIRGKSVAEALAILKFT---------------------------------PKAASPIVEKVLRSAVAN----A- EHNY-DLESANLYVSEAYVNEGATLKRFRPRAKGSASPIMKRTSHVVVVVSE-MFVKTGDKVKVIAGS------EK-GKE GTVLSVNVKEN--RVV--VKGVNMIKKATK----AS--AS-NAN-GGVVETEGSIHASNVKVIAKAES-------NK--D --------------------------------------------MGSKINPIGFRLG--VN-RDWEAKWYA------A-R G--YKETLNEDLRIRKFL--DEKLK-----DASVSTVEIERAA-N-RVNIAIHTARPGMVIGKGGAEVEALNKEINALVH INIVEIKK---PDLEAKLVADGIARQLEARIAFRRASRQAAQRSMRA-GAKGIKVQIAGRLNGADIARREWHTEGSVPL- -HTLRADIDYAWVNAFTTYGEIGVKVWINMVLTDPIADFLTRIRNANMAKHDSVEI-PASNIKKSLTEILKQEGFIRDYE VTE----D---G----KQGVIKITLKYG---PNG-------E---RVISGLKRISKPGLRNYVSADNLPKVLNGLGIAIV STSAGILTDKEAREKNVGGEVIAYVWMANEKIRIRLKSYEHSILDESGAKIVDTAKRTGAEISGPVPLPTERTLFTVLRS PHKNKDSR-EQFEMRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKLRHVYQGRVVSDKMDKTIVVVVDTYKNHPVYS KRTRYSKKYYAMDEN--NEAKVGDIVRIMETRPLSRTKRFRLVDIVKKS------------------------------- -MSRSI-KKGPFADA-HLLKKVDEQQA---AEKKQ----VIKTWSRRSTIFPSFVGLTIAVYDGRKHVPVFVTE-DMVGH KLGEFVPTRTFRGHK------A--DDK----ASK-------- >FIRM_Lactobacillus_delbrueckii_bulgaricus_ATCC_BAA-365 Concatenation of 2 sequences MAIKVYKPTSNGRRNMTSSDFAE-ITKS------------KP-EKTLLASKSKTAGRNSYGHITVRH-RGGGHKQQ---- YRIIDFK-R--TK-DNVKAKIVAIEYDPNRSANIALLHYT-DGTKAYILAPKGLTVGSWVESGV-D-AD-IKVGNALPLK NIPTGTEVHNIELKPGKGGQIARSAGTSAQVLGV--DGKYTQVRLQSGEVREILSECRATIGAVGNEQHSLINIGKAGRS -RWM-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPQPMTP---WGKKSRGIKTR-DSKKASE-K-LIIRHR --------------------------------MTK---G-ILGRKVGMTQIFT-KDGV---------LVPVTVIEATPNV VMQVK----TVE----N--DGY--EAVQLGY-------QD--KSNK----------PEKGHAK----------------- ---AK-TSPKRFIRELRG--------VELSDY-----EV---GS-EVTV--E-T-FKEGDVVNVTGTSRGHGYQGNIKRH HQSR-GPETHGS-RYHRI-PGSMG---SIIN-RVPKGKKLPGHMGVKTVTIENLVVEKVVADKN---------------- ----------VLMIKGN-VPGAKNSLIVVK-MANFKLMD-QNGNNA-GEVTLNDNVF----SV-EP-NEAVVFDAIIRQR AGKRQGTSKVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- RGGGVVFGPT-P-RSYAYSMPRKQRRLAIKSVLSQKLLDQ----------------N-LVVLDKL----TMD-A------ --PKTRLVV--S--DD--K---NVQLSAKNLPKVK-V---------------VPVNGLNVEDAVNYDK----LVLTQDDV KKIENSFATKYNEEI----VPALTKKFNYTSSMQVPKIDKIVLNMGVG-DAVANAKNLDEAVEELTLISGQKPMITKAKK SIANFRLREGMSIGAKVTLRGDRMYDFLSKLINVSLPRVRDFRGVST-RSFDGRGNYTLGVKEQLIFPEID-----FDKV NRTRGLDIVIVTT-----------------------AQTDEEARELLTQFGMPFMSRIG-L--KVINVPESVTVT-K--- -N-G--N-EITVKGPKGELTREF--DP-R--IKFEQED-GV--IRF------S--RSNENDK-AIHGTMRANLANMIEGV VNGYKKELKLIGVGY--RAVAKN-NV--LTLN--VGYSHPVEMKA-P-E-GVTVTTS--S-ATDVTIEG-ISKQVVGQFA AEIRAVR------SPEPY---KGKGIRYADEVVRRKEGK----------MIQTETRLKVADNSGARELLVIRVMG-SKRK T--GNIGDIVVAAVKQATPG-G-------VVKKGDVVKAVIVRTKSGARREDGSYIKFDENAAVIIN-ADKS-PRGTRIF GPVARELR-EGDFMKIVSLAPEVLMK-L--NELHPSEGS-RHARKRVG-RGTSSGF-GKTSGRGQKGQHARSGGN-T--- -RLGF-E-GGQMPLFRTMPK-RG--FKNVNLADLVDFEALKAK-GLVKVK---------VLG--NGD-L-N-V-K-LTV- KVNKVSEAAKSAIEAAGGTVMR---EFR--GKM---RGAA-KGGKTVAFG----------EYGLEAL--ESHWITNRQIE AARVAMTRYM------KRGGKVWIRIFPQKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-EKIMFEI--GG-- VSEETAREAMRLAASKLPIKCKF-VKNKLRLKRHRRVRGKI---SGTAERPRLSVFRSNTNIYAQLIDD---V--AGVTL ASASTL-DKSV-------S-KDA-TKVEQAQAVGKAIAEA--GKAKG-ITEVVFDRGGYIYH--GRVKALADAARENGLE F-------------------------------------------------------------ISS-ARAEARTVRIAPRK ARLVVDLIRGKSVAEALAILKFT---------------------------------PKAASPIVEKVLRSAVAN----A- EHNY-DLESANLYVSEAYVNEGATLKRFRPRAKGSASPIMKRTSHVVVVVSE-MFVKTGDKVKVIAGS------EK-GKE GTVLSVNVKKN--RVV--VKGVNMIKKATK----AS--AS-NAN-GGVVETEGSIHASNVKVIAKAES-------NK--D --------------------------------------------MGSKINPIGFRLG--VN-RDWEAKWYA------A-R G--YKETLNEDLRIRKFL--DEKLK-----DASVSTVEIERAA-N-RVNIAIHTARPGMVIGKGGAEVEALNKEINALVH INIVEIKK---PDLEAKLVADGIARQLEARIAFRRASRQAAQRSMRA-GAKGIKVQIAGRLNGADIARREWHTEGSVPL- -HTLRADIDYAWVNAFTTYGEIGVKVWINMVLTDPIADFLTRIRNANMAKHDSVEI-PASNIKKSLTEILKQEGFIRDYE VTE----D---G----KQGVIKITLKYG---PNG-------E---RVISGLKRISKPGLRNYVSADNLPKVLNGLGIAIV STSAGILTDKEAREKNVGGEVIAYVWMANEKIRIRLKSYEHSILDESGAKIVDTAKRTGAEISGPVPLPTERTLFTVLRS PHKNKDSR-EQFEMRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKLRHVYQGRVVSDKMDKTIVVVVDTYKNHPVYS KRTRYSKKYYAMDEN--NEAKVGDIVRIMETRPLSRTKRFRLVDIVKKS------------------------------- -MSRSI-KKGPFADA-HLLKKVDEQQA---AEKKQ----VIKTWSRRSTIFPSFVGLTIAVYDGRKHVPVFVTE-DMVGH KLGEFVPTRTFRGHK------A--DDK----ASK-------- >FIRM_Lactobacillus_fermentum_IFO_3956 Concatenation of 2 sequences MGIRKYKGTTNGRRNMNGYDFAE-ITKT------------TP-EKSLLAPLKHTAGRNNAGKMTVRH-RGGGTKRQ---- YRIIDFK-R--IK-DDVPATVKAIEYDPNRTANIALLGYA-DGTKSYILAPKGLKVGMTVQSGP-D-AD-IKVGNTLPLK NIPVGTVIHNIELKPGKGGQLTRSAGTSAQLLGK--EEKYVLVRLSSGEVRMILAACRATIGSIGNDEHGLLVKGKAGRS -RYA-----GQR-P-HVRGSVMNPNDHPHGGGEGKA-P--VGLPSPLSP---WGKKTVGKKTR-SHKARSN-K-FIVRGR --------------------------------MTK---G-ILGKKVGMTQVFT-DNGE---------LVPVTVIDVTPNV VMQVK----TLE----N--DGY--SAVQLGF-------DD--KSNK----------PEQGHAK----------------- ---AN-TTPKRFIGEIRD-------AELGDDI-----KV---GD-KVAA--D-I-FAEGETVDVTGTTKGHGYQGNIHKD GQRR-GPMAHGS-RYHRR-PGSLG---AIIN-HVFKGKKLPGRMGNNTRTVQHLRIVKVDTENN---------------- ----------VLLIKGN-VPGANKSFVTIK-MTSVALFK-QDGSQN-GTVELNDSVF----SV-EA-NESAEFDAILRQR ASLRQGTHAVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QF---- RGGGIVFGPT-P-RSYNYALPRKVRQLAIKSALSQKVAND----------------K-FVVVDGL----NFD-A------ --PKTKLVV--VTDED--K---NAQLSARNLPKTT-V---------------VTPAGVNILNVVDAQK----IIITQSAL SQVENRLKAKYENEV----RPSLIEKFDYSSVMAAPKLEKIVLNMGVG-DATQNSKNLDEAVEELGLISGQKPLITKAKK SIAGFRLREGMAIGAKVTLRGTRMYDFLDKLVNVSLPRVRDFRGVSN-KAFDGRGNYTLGVREQLIFPEID-----YDNV NRVRGLDIVIVTT-----------------------ANSDEEAHELLAQLGMPFMSRIG-Y--KEIDLPAGVEVS-Q--- -E-G--N-VVTVKGPKGTLSREI--SP-L--ITMSVEG-NV--VKF---ER-S--GEDNKVR-ALHGTTRANVNNMVEGV VNGFKKTLKLVGVGY--RAQFKG-DK--LILT--VGYSNPVEMTK-P-A-EVEIAVP--D-NTTIEISG-IDKQEVGDFA AEVRAVR------SPEPY---KGKGIRYENEHIVRNEGK----------MIQQESRLKVADNSGAREILVIKILG-SRVK T--GNIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKHGLHRKDGSYIKFDENAAVLIN-NDKS-PKGTRIF GPIARELR-DDDYMKIISLAPEVLMQ-L--NELKPVAGS-RFKRLRKG-RGLSSGH-GFTSGRGTKGQKAH--GK-T--- -RLGF-E-GGQMPLYRQKPK-RG--FTSVSLTTLVTPEVLVAN-GVIKVK---------VLA--TGK-L-E-K-K-LTV- KANKFSASAVKAIEAAGGTT-K---VQR--GKM---RGEA-KGGKTVTFG----------EFGLQAL--DSHWISNRQIE AARIAMTRYM------KRGGKVWIKIFPHLSYTSKGVGTRMGNGK---------GAPEGWVAPVKR-MKVMFEV--AG-- VPEEVAREALRLAGNKLPVRTKI-VKNKIRQRRHMRVRGKI---SGTAERPRLSVYRSNKNIYAQLIDD---V--KGVTL ASASTQ-DTEV---------SGK-TKTEQAAGVGALIAKR--GVEKN-VTTVVFDRGGYLYH--GRVQALAEAARENGLQ F-------------------------------------------------------------VTS-AKATAKMVRVSSRK VRLVLDTIRNKSVAEAFAILKFT---------------------------------PNGAASDVEKVLKSAVAN----A- ENNF-DLDQASLVVSEAFANEGPTLKRFRPRAKGSASPINKRTSHITVVVAE-MFLKTGDKVRVITGK------DK-GQE GTIKKTFAKEN--RVI--VEGVNKIKKHQK----PS--NM-NPN-GGIIDTEAPINASNVM-LLDPST-------NE--P --TRVGFEV----V--------DGKVR---VAKKSG---KQI--MGQKINPNGFRVG--VI-RDWTAKWYA------D-K N--YAAYLNEDLRIRKYI--EKRLA-----DASVSTVEIERAA-N-RVNVSIHTAKPGMVIGKGGSEVEALRKELNNLVH INVVEIKK---PDLDAHLVGESVAEQLENRIAFRRAMRGAMQRTMRA-GAKGIKIQVAGRLNGADMSRIESYSDGTVPL- -HTLRADIDYSWDEAHTTYGVLGIKTWIYMSMSDPIADFLTRIRNANMAHHDSVEA-PASKMKKDIAEILKQEGFIRDVE YVE----D---N----KQGIIRVFLKYG---QDG-------E---RVISGLKRISKPGLRSYVKADAVPKVLNGLGIAII STSNGVVTDKVARAKKVGGEVVAYIWMANQKIRIRLKAYEHRVLDESADKIVESAKRTGAQVSGPIPLPTERTLYTVIRS PHKFKKSR-EQFEMRTHKRLIDIIDPTPKTVDALMKLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVVIDTYKSAPIYG KRVKYSKKYYAHDAN--NEAHVGDTVQIMETRPLSAKKRFRLVKVVEKA------------------------------- -MGRSL-KKGPFADA-SLLKKVEAQAD---SDKKT----VIKTWSRRSTIFPSFIGYTFAVYDGRKHVPVYVQE-DMVGH KLGEFVPTRTFRGHA------A--DDK----KTG------RK >FIRM_Lactobacillus_gasseri_ATCC_33323 Concatenation of 2 sequences MAIIKYKPTTNGRRNMTSSDFAE-ITKK------------KP-EKTLLESQSHTAGRNSYGHITVRH-RGGGHKQK---- YRIIDFK-R--NK-DDVKAVVKAIEYDPNRTANIALLHYT-DGIKAYILAPKDLKVGTVVESGP-N-AD-IKPGNALPLS AIPAGTEIHNIELKPGKGGQLVRSAGTVAQVLGN--DGKYTLVRLQSGEVRKILSTCRATIGSVGNEQHSLIQLGKAGRK -RWL-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPQPMTP---WGKKSRGIKTR-NSKARSE-K-LIIRHR --------------------------------MTK---G-ILGRKVGMTQIFT-KNGI---------LVPVTVIEATPNV VLQVK----TNE----S--DGY--EAVQVGY-------QD--MSNK----------PAKGHAK----------------- ---AK-TSPKRFIREIRD--------VELKDY-----EV---GS-EITV--D-S-FSEGDVVDVTGTTRGHGTQGNIKRW GQSR-GPETHGS-RYHRI-PGSMG---SIIN-RVPKGKKLPGHMGGKKVTVQNLVIEKVVPEKN---------------- ----------VLLVKGN-VPGAKNSLIFVK-MANLEIID-QKGKSA-GNVDLNEEIF----GI-EP-NESVVFDAIIRQR AGKRQGTSAVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- RGGGTVFGPT-P-RSYKMDMPRKARRLAMKSVLSQKVADK----------------D-LIILDQL----TLE-A------ --PKTKLVV--S--DD--K---NVQLSGKNLPKVK-V---------------VPVNGLNVVDAVDYQK----LVLTQDAI KRIENSLVEKYSNEI----APAMNKKFNYDSVMEIPKIDKIVLNMGVG-DAVSNAKNLDEAVEELTLISGQKPLITKAKK SIANFRLREGMSIGAKVTLRGDRMYDFLYKLINVSLPRVRDFRGISS-RSFDGRGNYTLGIKEQLIFPEID-----YDKV NRVRGLDVVIVTT-----------------------ANTDEEARELLTEFGMPFMSRIG-L--KVIEVPEKVTVT-K--- -N-G--D-DITVKGPKGELTRYF--DP-R--ITFEQKD-GE--IHF------S--RSSEADK-ALHGTERANLASMIEGV TDGYVKKLTLVGVGY--RAVAQG-KK--LTLN--VGYSHPVVFEA-P-E-GVTVKTP--S-ATSIEIEG-ISKQVVGQFA AEIRDVR------PPEPY---KGKGIRYEDEYVRRKEGK----------MIQHESRLKVADNSGARELLVIKILG-SKRK T--GNIGDIVVAAVKQATPG-G-------VVKKGDVVKAVIVRTKSGARREDGSYIKFDENAAVVIN-ADKS-PRGTRIF GPVARELR-EHDFMKIVSLAPEVLMK-L--NELKPNEGS-RRNRKRVG-RGTSSGY-GKTAGRGQKGQLARTGGK-T--- -RLGF-E-GGQMPLFRRMPK-RG--FKNINLNDLVTIDTLKSS-GLVKVK---------LLA--NGE-L-K-V-K-LTV- KVNKVSEAAKKAVEAAGGTV-R---EFR--GKM---RGEA-KGGKTIAFG----------EYGLEAV--ESHWITNRQIE AARIAMTRFM------KRGGRVWIRIFPQKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-GKIMFEI--GG-- VSEDVAREALRLASNKLPIKTKF-VKNKLRLKRHKRIRGKI---SGTAERPRLSVFRSNKNIYAQLIDD---V--EGVTL ASASTN-DKNI--------SAEG-SKMEQAAEVGKALAET--AAKKN-IKSVVFDRSGYLYH--GRVQALADAARENGLE F-------------------------------------------------------------ISS-AKAEARTVRIAPRK ARLVVDLIRGKSVAEALAILQFT---------------------------------PRAASPIVEKVLKSAIAN----A- EHNY-DLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSE-MFVKTGDKVKVIAGK------DK-GKE GTVLSVNAKTN--RIV--VKGVNKIKKHEK----PS--QA-NAN-GGVVEKEGSIHASNVK-VIAKKE-----------D ------------------------NNK-----------------MGQKINPNGFRLG--VN-RDWEAKWYA------D-K N--YADTLNEDLRIRKFI--SEKLA-----DASVSTVEIERAA-N-RINISIHTAKPGMVIGKGGKEVEALRKQLSALVH INIVEIKK---PDLDAKLVGEGIARQLEARIAFRRATRQATQRSMRS-GAKGIKVQTAGRLNGADMARREWHTEGSVPL- -HTLRADIDYAWVEAATTYGQIGVKVWINMVMTDPIADYLTRIRNANMAKHSSVEI-PASSMKKSLSEILKNEGFIRDYQ VED----D---N----KQGMIKIFLKYG---PNN-------E---RVISGLKRISKPGLRNYVSAENLPKVLNGLGIAII STSAGVITDKEAREKNVGGEVIAYVWMASQQIRIRLKSYEHGILDESAAKIVATAERTGAQISGPVPLPTERTLFTVLRS PHKNKDSR-EQFEIRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKLRHVYQGRVVSDKMDKTITVVVDTYKNHPVYK KRIKYSKKYYAHDEN--NEAKIGDTVRIMETRPLSHAKRYRLTKIVKKS------------------------------- -MSRSI-KKGPFADA-SLLKKIEAQEG---SEKKQ----VIKTWSRRSTIFPSFVGFTIAVYDGRKHVPVYITE-DMVGH KLGEFVPTRTFRGHK------V--ADKATTTVGK-------- >FIRM_Lactobacillus_helveticus_DPC_4571 Concatenation of 2 sequences MAIKIYKPTTNGRRHMTSSDFAE-ITKT------------KP-EKTLLESQSHTAGRNSYGHITVRH-RGGGHKQK---- YRIIDFK-R--NK-DNTKAVVKAIEYDPNRTANIALLHYT-DGIKAYILAPKGLKVGDIVESGD-S-VD-IKPGNALALK NIPSGTSIHNIELKPGKGGQLVRSAGASAQVLGV--DGDYTLVRLQSGEVRKILSSCRATIGVVGNEQHSLIKLGKAGRK -RWL-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPQPMTP---WGKKARGIKTR-DTKKASE-K-LIIRRR --------------------------------MTK---G-ILGRKVGMTQIFT-KDGV---------LVPVTVVEATPNV VMQVK----TVE----S--DGY--EAVQLGY-------QD--KSNK----------PEKGHAK----------------- ---AK-TSPKRFIREIRG--------VELKDY-----EV---GS-EVTV--D-T-FKEGDVVNVTGTSRGHGYQGNIKRW GQSR-GPETHGS-RYHRI-PGSMG---SIIN-RVPKGKRLPGHMGMKKVTIENLVIEKVVADKN---------------- ----------VLMIKGN-VPGAKNSLIVVK-MANLKVMD-QNGKDS-GEVTLNDKVF----GI-EP-NESVVFETIIRQR AGKRQGTSKVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGTVFGPT-P-RSYAYTMPRKQRRLAIKSVLSQKMIDK----------------D-LIVLDKL----AMS-A------ --PKTKLIV--S--DD--N---NVQLSARNLAKVK-A---------------VPVNGLNVEDAVNYGK----LILTQDAV KKIESYLAEEYKEKV----APALAEKFDYKSSMQIPKIDKIVLNMGVG-DAVSNAKNLDEAVEELTLISGQKPLITKAKK SIANFRLREGMSIGAKVTLRGDRMYDFLYKLINVSLPRVRDFRGVST-RSFDGRGNYTLGVKEQLIFLEID-----FDKV NRTRGLDIVIVTT-----------------------ANTDEEARELLTQFGMPFMSRIG-L--KTIEVPDSVTVT-K--- -D-G--D-NITVKGPKGELTRYF--DP-K--ITFEQKD-GE--INF------S--RSSESDK-ALHGTERANLASMIEGV VNGYKKTLKLIGVGY--RAQAQG-NK--VTLN--VGYSHPVVLTA-P-E-GVTVKAT--S-ATDVEVEG-VSKQDVGQFA AEIRAVR------PPEPY---KGKGIRYVDEYVRRKEGK----------MIQNESRLKVADNSGARELLVIRVLG-SKRK T--GNIGDIVVCTVKQATPG-G-------VVKKGDVVKAVIVRTKSGARREDGSYIKFDENAGVIIN-ADKS-PRGTRIF GPVARELR-EYDFMKIVSLAPEVLMK-L--HELHSAEGS-RRNRKRVG-RGTSSGY-GKTSGRGQKGQLARQGGH-T--- -RLGF-E-GGQMPLFRTMPK-RG--FKNVNLDDLVTVETLKEN-GLVKVK---------LLG--NGE-L-K-V-K-LTV- KVNKVSAAAKKAVEAAGGTVMR---EFR--GKM---RGAA-KGGKYIAFG----------EYGLEAL--ESHWITNRQIE AARVAMTRYM------KRGGKVWIRIFPQKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-EKIMFEI--GG-- VDEATAREALRLASTKLPIKTKF-V---MRLKRHKRIRGKI---SGTAERPRLSIFRSNKNIYAQLIDD---V--AGVTL ASASSL-DENV--------SEDA-TKVEQATAVGKAIAEA--AKAKN-ISTVVFDRSGYLYH--GRIQALADAARENGLD F-------------------------------------------------------------ISS-AKAEARTVRIAPRK ARLVVDLIRGKSVAEALAILEFT---------------------------------PRAASPIVEKVLRSAIAN----A- EHNY-DLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSE-MFVKTGDKVKVIAGK------DK-GKE GTVLSINVKKN--RVV--VKGVNKIKKHQK----PS--QT-NAN-GGVVESEGSIHASNVK-VISKKE-------DK--- --------------------------------------------MGQKINPNGFRLG--VI-HDWESKWYA------D-K G--YKETLNEDLRIRKFI--SKKLK-----DASVSTVEIERAA-N-RINISIHTAKPGMVIGKGGSEVEALRKQLNALVH INIVEIKK---PDLDAELVADSIARQLEARIAFRRAMRQATQRAMRA-GAKGIKVQTSGRLNGADMARREWHTEGRVPL- -QTLRADIDYAWVNAFTTYGEIGVQVWINMVMTDPIADYLTRIRNANMAKHDSVEI-PASNIKKSISEILKREGFIRDYE VAD----D---N----KQGVIKVFLKYG---PNG-------E---RVISGLKRISKPGLRNYVSAEDLPKVLNGLGIAIV STSAGVITDKEARQKNVGGEVIAYVWMASQTIRIRLKSYEHGILDESAAKIVATAKRTGAEISGPVPLPTERTLFTVLRS PHKNKDSR-EQFEMRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKLRHVYQGRVVSDKMDKTIVVVVDTYKNHPVYS KRIRYSKKYYAQDEN--NEAKVGDTVRIMETRPLSRKKRFRLVKIVKKS------------------------------- -MSRSI-KKGPFADA-SLLKKVDAQAD---ADKKQ----VIKTWSRRSTIFPSFVGLTIAVYDGRKHVPVYITE-DMVGH KLGEFVPTRTFHGHK-------STEDK---TTAK-------- >FIRM_Lactobacillus_johnsonii_NCC_533 Concatenation of 2 sequences MAIIKYKPTTNGRRNMTSSDFAE-ITKK------------KP-EKTLLESQSHTAGRNSYGHITVRH-RGGGHKQK---- YRIIDFK-R--NK-DDVKAVVKAIEYDPNRTANIALLHYT-DGIKAYILAPKGLKVGAVVESGP-D-AD-IKPGNALPLS AIPAGTEIHNIELKPGKGGQLVRSAGTVAQVLGN--DGKYTLVRLQSGEVRKILSTCRATIGSVGNEQHSLIQLGKAGRS -RWL-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPQPMTP---WGKKSRGIKTR-NSKARSE-K-LIIRHR --------------------------------MTK---G-ILGRKVGMTQIFT-KNGI---------LVPVTVIEATPNV VLQVK----TNE----S--DGY--EAVQVGY-------QD--MSNK----------PAKGHAK----------------- ---AK-TSPKRFIREIRD--------VELKDY-----EV---GS-EITV--D-S-FSEGDVVDVTGTTRGHGTQGNIKRW GQSR-GPETHGS-RYHRI-PGSMG---SIIN-RVPKGKKLPGHMGGKKVTVQNLVIEKVVPEKN---------------- ----------VLLIKGN-VPGAKNSLIFVK-MANLEIID-QKGKSA-GNVDLNEEIF----GI-EP-NESVVFDAIIRQR AGKRQGTSAVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- RGGGTVFGPT-P-RSYKMDMPRKARRLAMKSVLSQKVADN----------------D-LIILDQL----TLE-A------ --PKTKLVV--S--DD--K---NVQLSGKNLPKVK-V---------------VPVNGLNVVDAVDYQK----LVLTQDAI KRIENSLVEKYSNEI----APAMNKKFNYDSVMEIPKIDKIVLNMGVG-DAVSNAKNLDEAVEELTLISGQKPLITKAKK SIANFRLREGMSIGAKVTLRGDRMYDFLYKLINVSLPRVRDFRGISS-RSFDGRGNYTLGIKEQLIFPEID-----YDKV NRVRGLDVVIVTT-----------------------AKTDEEARELLTEFGMPFMSRIG-L--KVIEVPEKVTVT-K--- -N-G--D-DITVKGPKGELTRYF--DP-R--ITFEQKD-GE--IHF------S--RSSEADK-ALHGTERANLASMIEGV TDGYVKKLTLVGVGY--RAVAQG-KK--LTLN--VGYSHPVEFEA-P-E-GITVKTP--S-ATSIEIEG-ISKQVVGQFA AEIRDVR------PPEPY---KGKGIRYEDEYVRRKEGK----------MIQHESRLKVADNSGARELLVIKILG-SKRK T--GNIGDIVVAAVKQATPG-G-------VVKKGDVVKAVIVRTKSGARREDGSYIKFDENAAVVIN-ADKS-PRGTRIF GPVARELR-EHDFMKIVSLAPEVLMK-L--NELKPNEGS-RRNRKRVG-RGTSSGY-GKTAGRGQKGQLARTGGK-T--- -RLGF-E-GGQMPLFRRMPK-RG--FKNINLNDLVTIDTLKSS-GLVKVK---------LLA--NGE-L-K-V-K-LTV- KVNKASEAAKKAVEAAGGTV-R---EFR--GKM---RGEA-KGGKTIAFG----------EYGLEAV--ESHWITNRQIE AARIAMTRFM------KRGGKVWIRIFPQKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-GKIMFEI--GG-- VSEDVAREALRLASNKLPIKTKF-VKNKLRLKRHKRIRGKI---SGTAERPRLSVFRSNKNIYAQLIDD---V--EGVTL ASASTN-DKNI-SAEG--------SKMEQAAEVGKALAET--AAKKN-IKSVVFDRSGYLYH--GRIQALADAARENGLE F-------------------------------------------------------------ISS-AKAEARTVRIAPRK ARLVVDLIRGKSVAEALAILQFT---------------------------------PRAASPIVEKVLKSAIAN----A- EHNY-DLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSE-MFVKTGDKVKVIAGK------DK-GKE GTVLSVNAKTN--RIV--VKGVNKIKKHEK----PS--QT-NAN-GGVVEKEGSIHASNVK-VIAKK------------- -------------E--------DNK-------------------MGQKINPNGFRLG--VN-RDWEAKWYA------D-K N--YADTLNEDLRIRKFI--SEKLA-----DASVSTVEIERAA-N-RINISIHTAKPGMVIGKGGKEVEALRKELSALVH INIVEIKK---PDLDAKLVGEGIARQLEARIAFRRATRQATQRSMRS-GAKGIKVQTAGRLNGADMARREWHTEGSVPL- -HTLRADIDYAWVEAATTYGQIGVKVWINMVMTDPIADYLTRIRNANMAKHTSVEI-PASSMKKSLSEILKNEGFIRDYQ VED----D---N----KQGMIKIFLKYG---PNN-------E---RVISGLKRISKPGLRNYVSAENLPKVLNGLGIAII STSAGVITDKEAREKNVGGEVIAYVWMASQQIRIRLKSYEHGILDESAAKIVATAERTGAQISGPVPLPTERTLFTVLRS PHKNKDSR-EQFEIRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKLRHVYQGRVVSDKMDKTITVVVDTYKNHPVYK KRIKYSKKYYAHDEN--NEAKIGDTVRIMETRPLSHAKRYRLTKIVKKS------------------------------- -MSRSI-KKGPFADA-SLLKKIEAQEG---SEKKQ----VIKTWSRRSTIFPSFVGFTIAVYDGRKHVPVYITE-DMVGH KLGEFVPTRTFRGHK------V--ADKATTTVGK-------- >FIRM_Lactobacillus_plantarum_WCFS1 Concatenation of 2 sequences MGIKKYKPTTNGRRNMTASDFSE-ITKT------------KP-EKSLLDSQSHTAGRNSYGHITVRH-RGGGHKQQ---- YRLVDFK-R--IK-DEVPATVKAIEYDPNRTANIALLVYA-DGVKSYILAPKGLEVGMQVQSGA-E-AD-IKVGNALPLT NIPVGTVIHNIELKPGKGGQLARSAGTSAQLLGK--EGKYAIVRLSSGEVRLVLLTSRATIGTVGNEQHELINSGKAGRT -RWQ-----GKR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGHPSPMSP---WGKKTLGKKTR-NKKARSN-K-LIVRGR --------------------------------TTK---G-ILGKKVGMTQVFT-ESGE---------LVPVTVVEVQPNV VLQVK----TVE----N--DGY--EAIQLGV-------DD--KTNK----------PAQGHAK----------------- ---AK-TTPKRFIREIRN--------VELGDY-----TV---GD-EVKA--D-I-FAAGDAVDVTGITKGHGYQGNIHKD GQSR-GPMAHGS-RYHRR-PGSMG---AIIN-RVFKGKKLPGRMGNHQRTMQNLQIVRADVENN---------------- ----------VLLIKGN-VPGANKSFVTVK-MTSVALFK-QDGTQN-GDVTLNDAVF----GV-EP-NENVVFDAILMQR ASMRQGTHAVKNRSA--------RR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RKGGIVFGPT-P-RSYSYKLPKKVMRLALKSVLSQKVLDN----------------S-LVAVDSL----AFD-A------ --PKTKLVL--VEEDN--E---KAALAGRNLPNVK-I---------------LKAKGVNVLDVANSDK----LVVTQKAL DQLENRLKAQYEKEI----VPALVDKFNYTSVMQVPKLAKIVLNMGVG-DAVTNAKNLDEAVEELTLISGQKPLVTRAKK SIAGFRLREGMAIGAKVDLRGERMYDFLDKLINVSLPRVRDFHGVST-RSFDGRGNYTLGVREQLIFPEIN-----YDNV NRVRGLDIVIVTT-----------------------ADSDEESRELLTQFGMPFMSRIG-Y--KVIELPAGVEVS-Q--- -A-G--E-VVTVKGPKGTLTRNI-ASD----ITMTVEG-NE--VKF---TR-P--SDDYKMK-ALHGTTRANVNNMVEGV TKGFTKNLQLVGVGY--RAQLQG-KK--LVLS--VGYSHPVEFAT-P-E-NLTVEVP--D-NTHINISG-IGKQAVGDFA AEVRAVR------SPEPY---KGKGIRYVDEYVRRKEGK----------MIQQESRLKVADNSGAREILTIKVLG-SGRK T--ANIGDVIVATVKQATPG-G-------VVKAHDVVKAVIVRTKSGVHRADGSYIKFDENAAVIIR-DDKT-PQGTRIF GPVARELR-DKDFMRIVSLAPEVLMK-L--HELTPSEGS-RFSRRRIG-RGDSSGQ-GKTSGRGQKGQKARGK---V--- -RVGF-E-GGQMPLYRRIPK-RG--FTNVNLDGLVTPESLKEA-GLVKVK---------VLG--NGK-L-N-K-K-LTV- KASKFSATAVAAIEAAGGKT-R---VHR--GKM---RGEA-KGGKTVAFG----------DYGLQTL--ESHWISNRQIE AARVAMNRYM------KRGGKVWIKIFPHKSYTEKGVGVRMGNGK---------GTPAGWVAPVKR-NKIMFEV--AG-- VPEEVAREALRLAGTKLPVKTKI-VKNKTRQRRHARVRGKI---SGTAERPRLNVYRSNKNIYAQVIDD---V--EGVTL ASASTL-DSEV---------KGN-NKTEKAASVGEVVAKR--AAEKK-IVDVVFDRGGYLYH--GRVQALAEAARENGLK F-------------------------------------------------------------VTS-ARATAKTVRIAARK VRLVVDLIRGKSVAEALAILKFT---------------------------------PRGASPVVEKVLLSAVAN----A- ENNF-DLDREDLVVSEAFVNEGPTLKRFRARAKGSASPINKRTSHITITVTE-MLIKTGDKVRVISGK------DR-GQE GTVKKVISAKN--RIV--VEGVNKIKKHQK----PT--NV-NPQ-GGIVDIEAPIDASNVM-YLDPST-------NE--P --TRLGVRR----E--------DGRVR---YAKKSG---KDL--MGQKVNPTGLRVG--II-RDWEAKWYA------E-K D--FAAYLNEDLRIRKYI--EQRLA-----DASVSTVEIERAA-N-RVNISIHTAKPGMVIGKGGSEVEALRKELNNLVH INIIEIKK---PDLDAKLVGESIARQLEGRVAFRRAMRGAMQRTMRS-GAKGIKTQVAGRLNGADMSRVEAYSDGTVPL- -HTLRADIDYSWVEARTTYGKLGVKTWIY-MMTDPIADFLTRIRNANMVRHDSLEV-PASKIKRNIAEILKNEGFVRDVE YID----D---D----KQGIIRVFLKYG---KDN-------E---RVISGLKRISKPGLRSYVKADAVPKVLNGLGIAII STSEGVITDKEARAKKLGGEVLAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGATISGPIPLPTERTIYTVLRS PHKFKDSR-EQFEMRTHKRLIDIVNPTPKTVDSLMKLDLPSGVDIEIKLRKVIQGRVVSDKMDKTIVVIVETYKNHPVYG KRVRYSKKFKAHDEK--NEAKTGDIVKIMETRPLSATKRFRLIEVVQKA------------------------------- -MGRSL-KKGPFADA-HLLKKIDAQSD---SDKKS----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQD-DMVGH KLGEFVPTRTFHGHG------T--DDK----KTK-------- >FIRM_Lactobacillus_reuteri_F275 Concatenation of 2 sequences MGIRKYKATTNGRRNMNGYDFAE-ITKT------------TP-EKSLLAPLKHTAGRNSYGHITVRH-RGGGTKRQ---- YRIIDFK-R--IK-DDVPATVKAIEYDPNRTANIALLVYA-DGTKSYIIAPKGLKVGMTVQSGP-D-AD-IKVGNALPLK NIPVGTVIHNIELKPGKGGQLARSAGASAQLLGK--EEKYVLVRLSSGEVRMVLATCRATIGTVGNDEHALIIKGKAGRT -RYA-----GQR-P-HVRGSVMNPNDHPHGGGEGKQ-P--VGLPSPLSP---WGKKTVGKKTR-SHKARSN-K-FIVRGR --------------------------------MTK---G-ILGKKVGMTQVFT-DNGE---------LVPVTVIDVTPNV VMQIK----TVE----N--DGY--SAVQLGF-------DD--KSNK----------PEQGHAK----------------- ---AN-TTPKRFIGEIRD--------AELGDI-----KV---GD-EVKA--D-V-FAEGETVDVTGTTKGHGYQGNIHKD NQSR-GPMAHGS-RYHRR-PGSLG---AIIN-RVFKGMKLPGRMGGKTVTMQHLQVVKVDLDNN---------------- ----------VLLIKGN-VPGANKSYVTIK-MTSVNLYK-QDGSQN-GTVELNDAVF----GV-EP-NENVVFDAILRQR ASLRQGTHAVKNRSA--------VS-GGGKKPW---------RQKGTGRAR--------QGS---IR-SP----QF---- RGGGIVFGPT-P-RSYKYSLPRKVRQLAIKSALSQKVLDN----------------S-FVVVDAL----NFD-A------ --PKTKLVV--VTDDD--K---NAALSARNLANAT-V---------------VTPAGVNILNVVDNQK----IVITKSAL SQVENRLKAKYENEI----RPALIEKFNYSSVMQAPKIDKIVLNMGVG-DATTNSKNLDEAVEELGLISGQKPLITKAKK SIAGFRLREGMSIGAKVTLRGERMYDFLDKLVNVALPRVRDFHGVSN-KAFDGRGNYTLGIHEQLIFPEID-----YDKV NRVRGLDVVIVTT-----------------------AQTDEESRELLAQLGMPFMSRIG-Y--KEIDLPSGVEIS-Q--- -D-G--N-VVTVKGPKGTLSREI--SP-L--IKMTIDG-NV--VKF---DR-D--ADTNKLK-MLHGTTRANVNNMVEGV VDGYKKVLKLVGVGY--RAQLKG-NK--LILT--VGYSNPVEMDK-P-E-DVEINVP--D-NTTIELSS-INKEHLGNFA AEVRAVR------SPEPY---KGKGIRYENEHIIRKEGK----------MIQQESRLKVADNSGAREILVIKILG-SRVK T--GNIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKHGIHRKDGSYIKFDENAAVLIN-NDKS-PKGTRIF GPIARELR-GDDFMKIVSLAPEVLMK-L--NELKPATGS-RSKRLRKG-RGLSSGH-GFTSGRGTKGQKAHGKT------ -RLGF-E-GGQMPLYRQIPK-RG--FTNVNLASLVTPQLLMES-GLVKIK---------VLG--SGK-L-E-K-K-LTV- KANKFSASAVSAIEAAGGKT-K---VQR--GHM---RGEA-KGGKTVTFG----------EFGLQAL--DSHWISNRQIE AARIAMTRYM------KRGGKVWIKIFPQLSYTSKGVGVRMGNGK---------GAPEGWVAPVKR-GKVMFEV--GG-- VSEEVAREALRLAGHKLPVRTKI-VKNKIRQRRHLRVRGKI---SGTAERPRLSVYRSNKNIYAQLIDD---V--KGVTL ASASTN-DSEV---------SGK-TKTEQASGVGALIAKR--ANEKN-ITEVVFDRGGYLYH--GRVQALAEAARENGLK F-------------------------------------------------------------ITS-AKATAKMVRVSARK VRLVLDAIRGKSVAEAFAILKFT---------------------------------PRGAASDVEKVLKSAVAN----A- ENNF-DLDRASLVVSEAFANEGPTLKRFRPRAKGSASPINKRTSHITVVVTE-MFIKTGDKVRVIAGK------DK-GKE GTIKKVLASQN--RVI--VEGVNIVKKHQK----PS--NS-NPN-GGVIDTEAAINASNVM-LIDPST-------NE--P --TRVGYKF----V--------DGKVR---VAKKSG---KTL--MGQKINPNGFRVG--VI-RDWTAKWYA------D-K D--FADYLNEDLRIRKYI--EKRLA-----DASVSTVEIERAA-N-RVNVSIHTAKPGMVIGKGGSEVEALRKELNKLVH INIVEIKK---PDLDAHLVGESIARQLEARIAFRRAMRGAMQRAMRA-GAKGIKTQVAGRLNGADMSRIESYSDGTVPL- -HTLRADIDYSWDEANTTYGVLGVKTWIYMSMSDPIADFLTRIRNANMAQHESVEA-PASKMKKDIAEILKNEGFIRDVE YVD----D---N----KQGIIRVFLKYG---NDG-------Q---RVISGLKRISKPGLRTYVKSDAVPKVLNGLGIAII STSEGVVTDKVARAKKIGGEVIAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGAQISGPIPLPTERTIYTVIRS PHKFKKSR-EQFEMRTHKRLIDIVDPTPKTVDSLMKLDLPSGVDIEIKLRKVYQGHVVSDKMDKTITVVIDTYKSAPIYG KRVKYSKKYYAHDEN--NEAKTGDTVQIMETRPLSAKKRFRLVKIVEKA------------------------------- -MGRSL-KKGPFADA-SLLKKVKEQEG---SEKKT----VIKTWSRRSTIFPSFIGYTFAVYDGRKHVPVYVQE-DMVGH KLGEFVPTRTFHGHA------S--DDK----KTG------K- >FIRM_Lactobacillus_reuteri_F275,_JCM1112 Concatenation of 2 sequences MGIRKYKATTNGRRNMNGYDFAE-ITKT------------TP-EKSLLAPLKHTAGRNSYGHITVRH-RGGGTKRQ---- YRIIDFK-R--IK-DDVPATVKAIEYDPNRTANIALLVYA-DGTKSYIIAPKGLKVGMTVQSGP-D-AD-IKVGNALPLK NIPVGTVIHNIELKPGKGGQLARSAGASAQLLGK--EEKYVLVRLSSGEVRMVLATCRATIGTVGNDEHALIIKGKAGRT -RYA-----GQR-P-HVRGSVMNPNDHPHGGGEGKQ-P--VGLPSPLSP---WGKKTVGKKTR-SHKARSN-K-FIVRGR --------------------------------MTK---G-ILGKKVGMTQVFT-DNGE---------LVPVTVIDVTPNV VMQIK----TVE----N--DGY--SAVQLGF-------DD--KSNK----------PEQGHAK----------------- ---AN-TTPKRFIGEIRD--------AELGDI-----KV---GD-EVKA--D-V-FAEGETVDVTGTTKGHGYQGNIHKD NQSR-GPMAHGS-RYHRR-PGSLG---AIIN-RVFKGMKLPGRMGGKTVTMQHLQVVKVDLDNN---------------- ----------VLLIKGN-VPGANKSYVTIK-MTSVNLYK-QDGSQN-GTVELNDAVF----GV-EP-NENVVFDAILRQR ASLRQGTHAVKNRSA--------VS-GGGKKPW---------RQKGTGRAR--------QGS---IR-SP----QF---- RGGGIVFGPT-P-RSYKYSLPRKVRQLAIKSALSQKVLDN----------------S-FVVVDAL----NFD-A------ --PKTKLVV--VTDDD--K---NAALSARNLANAT-V---------------VTPAGVNILNVVDNQK----IVITKSAL SQVENRLKAKYENEI----RPALIEKFNYSSVMQAPKIDKIVLNMGVG-DATTNSKNLDEAVEELGLISGQKPLITKAKK SIAGFRLREGMSIGAKVTLRGERMYDFLDKLVNVALPRVRDFHGVSN-KAFDGRGNYTLGIHEQLIFPEID-----YDKV NRVRGLDVVIVTT-----------------------AQTDEESRELLAQLGMPFMSRIG-Y--KEIDLPSGVEIS-Q--- -D-G--N-VVTVKGPKGTLSREI--SP-L--IKMTIDG-NV--VKF---DR-D--ADTNKLK-MLHGTTRANVNNMVEGV VDGYKKVLKLVGVGY--RAQLKG-NK--LILT--VGYSNPVEMDK-P-E-DVEINVP--D-NTTIELSS-INKEHLGNFA AEVRAVR------SPEPY---KGKGIRYENEHIIRKEGK----------MIQQESRLKVADNSGAREILVIKILG-SRVK T--GNIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKHGIHRKDGSYIKFDENAAVLIN-NDKS-PKGTRIF GPIARELR-GDDFMKIVSLAPEVLMK-L--NELKPATGS-RSKRLRKG-RGLSSGH-GFTSGRGTKGQKAHGKT------ -RLGF-E-GGQMPLYRQIPK-RG--FTNVNLASLVTPQLLMES-GLVKIK---------VLG--SGK-L-E-K-K-LTV- KANKFSASAVSAIEAAGGKT-K---VQR--GHM---RGEA-KGGKTVTFG----------EFGLQAL--DSHWISNRQIE AARIAMTRYM------KRGGKVWIKIFPQLSYTSKGVGVRMGNGK---------GAPEGWVAPVKR-GKVMFEV--GG-- VSEEVAREALRLAGHKLPVRTKI-VKNKIRQRRHLRVRGKI---SGTAERPRLSVYRSNKNIYAQLIDD---V--KGVTL ASASTN-DSEV---------SGK-TKTEQASGVGALIAKR--ANEKN-ITEVVFDRGGYLYH--GRVQALAEAARENGLK F-------------------------------------------------------------ITS-AKATAKMVRVSARK VRLVLDAIRGKSVAEAFAILKFT---------------------------------PRGAASDVEKVLKSAVAN----A- ENNF-DLDRASLVVSEAFANEGPTLKRFRPRAKGSASPINKRTSHITVVVTE-MFIKTGDKVRVIAGK------DK-GKE GTIKKVLASQN--RVI--VEGVNIVKKHQK----PS--NS-NPN-GGVIDTEAAINASNVM-LIDPST-------NE--P --TRVGYKF----V--------DGKVR---VAKKSG---KTL--MGQKINPNGFRVG--VI-RDWTAKWYA------D-K D--FADYLNEDLRIRKYI--EKRLA-----DASVSTVEIERAA-N-RVNVSIHTAKPGMVIGKGGSEVEALRKELNKLVH INIVEIKK---PDLDAHLVGESIARQLEARIAFRRAMRGAMQRAMRA-GAKGIKTQVAGRLNGADMSRIESYSDGTVPL- -HTLRADIDYSWDEANTTYGVLGVKTWIYMSMSDPIADFLTRIRNANMAQHESVEA-PASKMKKDIAEILKNEGFIRDVE YVD----D---N----KQGIIRVFLKYG---NDG-------Q---RVISGLKRISKPGLRTYVKSDAVPKVLNGLGIAII STSEGVVTDKVARAKKIGGEVIAYVWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGAQISGPIPLPTERTIYTVIRS PHKFKKSR-EQFEMRTHKRLIDIVDPTPKTVDSLMKLDLPSGVDIEIKLRKVYQGHVVSDKMDKTITVVIDTYKSAPIYG KRVKYSKKYYAHDEN--NEAKTGDTVQIMETRPLSAKKRFRLVKIVEKA------------------------------- -MGRSL-KKGPFADA-SLLKKVKEQEG---SEKKT----VIKTWSRRSTIFPSFIGYTFAVYDGRKHVPVYVQE-DMVGH KLGEFVPTRTFHGHA------S--DDK----KTG------K- >FIRM_Lactobacillus_sakei_sakei_23K Concatenation of 2 sequences MGIIKYKPTTNGRRNMTSSDFAE-ITKT------------TP-EKTLLESQSHTAGRNAHGHITVRH-RGGGHKQY---- YRVIDFK-R--IK-DDIKATVKSIEYDPNRTSNIALIQYP-DGIKAYIIAPKGLEVGMIVESGV-N-AD-IKVGNALPLA NIPDGTLIHNIELKPGKGGQLVRSAGTSAQLLGK--EGKYAIVRLTSGETRMILLTCRATVGTVGNGQHELIKIGKAGRK -RWM-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGRPSPMSP---WGKKTLGKKTR-SSKARSE-K-LIIRHR --------------------------------TTK---G-ILGRKVGMTQVFT-ENGE---------LIPVTVIAATPNV VLQVK----TNE----T--DGY--EAIQVGF-------ED--KSNK----------PAKGHVK----------------- ---AN-TTPKRFIREFRD--------VALGDY-----EV---GT-EIKV--D-T-FAAGDVVDVTGVTKGHGFQGNIKKD GQSR-GPMGHGS-RYHRR-PGSMG---AVIN-RVFKGKLLPGRMGNNQRTVQNLVVVSTDVEKN---------------- ----------VILVKGN-VPGAKNSMVTIK-MANVTLFK-QDGSQN-GNVELNDSIW----AI-EP-NENVVFDAIIMQR ASLRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYSYKLPRKVRRLAIKSVLSQKVIDN----------------D-LIVVDSF----SFD-A------ --PKTKLVV--LEDGN--D---FTALSARNLPNVT-V---------------VPADGINVLDVVGNQK----LILTQAAL SKIENRLKEKYVKEM----TPALIEKFNYTSSMQVPKIEKIVLNMGVG-DAVSNAKNLDKAVEELGLIAGQKPLITKAKK SIAGFRLREGMPIGAKVTLRGERMYDFLDKLVNVSLPRVRDFHGVSA-KSFDGRGNYTLGVREQLIFPEID-----YDKV DRVRGLDVVIVTT-----------------------SNTDEEARELLTQFGMPFMSRIG-L--KVIEVPAGVTVT-K--- -D-G-EN-NITVKGPKGELTRHF--NP-I--IEMHEEG-NL--INF---TR-S--SD--SDR-AMHGTMRANLNNMILGV TEGFKKTLDLIGVGY--RAQLKG-KT--LVLN--VGYSHPVEMEA-P-E-GVNVEVP--S-NTNIIISG-ISKQKVGQFA AEIRDVR------PPEPY---KGKGIRYTDEHVRRKEGK----------MIQSESRLKVADNSGAREILTIKVLG-SGRK T--ANIGDVIVATIKQATPG-G-------VVKKGEVVKAVIVRTKSGARRVDGSYIKFDENAAVIIN-DDKT-PKGTRIF GPVARELR-DSDFMKIVSLAPEVLMK-L--HELKPNEGA-RDVRKRVG-RGTSSGT-GKTAGRGQKGQKARSKV------ -RLGF-E-GGQMPLFRRMPK-RG--FKNVNLNDLITATVLIEA-GVVKVK---------VLA--NGE-L-N-K-K-LNI- KVSKYSEAAKAAVEAAGGSI-R---EFR--GKM---RGAA-KGGKEVTFG----------EFGLQAL--ESSWITNRQIE AARVAMTRYM------KRGGKVWIKIFPHKSYTAKGVGVRMGSGK---------GAPAGWVAVVKR-EKIMFEI--GG-- VSEEVAREALRLASHKLPVKTKI-VKNKTRQKRHTRVRGKI---SGTADCPRLNVFRSNKNIYAQLIDD---V--AGVTL ASASTL-DKEV-K-------VEG-TKVEQAQQVGALVAQR--AVKAG-HKVVVFDRGGYLYH--GRIAALATAARENGLE F-------------------------------------------------------------ITS-ATASAMSVRMPARK VRMVIDLIRGKSVAEAIAILEFT---------------------------------PRAASPVVIKVLKSAIAN----A- EHNY-DLDAENLVVTKAYANEGPTLKRFRPRAKGSASPINKRTSHITVVVSE-MFVKTGDKVKVISGK------DK-GKE GTIIKAMPKEG--RVV--VEGINTIKKHVK----PN--AQ-NPN-GGIVDTEASIDASNVM-LIDPSN-------NE--A --TRVGYKV----V--------DGKVR---VSKKTG---ESI--MGQKINPTGFRVG--VI-RDWDAKWYA------E-K D--FATFLHEDLKIRKYI--NTKLA-----DASVSTIEIERAA-N-RVNVSIHTAKPGMVIGKGGSEVENLRKALNNLVH INIVEIKK---PDLDAHLVGEGIARQLEARVAFRRAQRQAMQRTMRA-GAKGIKTQVAGRLNGADMSRIETHAQGTVPL- -HTLRADIDYSWDEAMTTYGKLGVKTWIYMVMTDPIADYLTRIRNANMVRHESLEV-PASRIKKDISEILKREGFIRDYE VIE----D---D----KQGIIRVFLKYG---KNN-------E---RVISGLKRISKPGLRNYVKANEVPKVLNGLGIAII STSNGVVTDKEAREKAAGGEVLAYVWMAKQKIRIRLKAFEHRILDQSADKIVETAKRTGASISGPIPLPTERTLYTVLRS PHKHKDSR-EQFEMRTHKRLIDIVNPTPKTVDSLMKLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVMVETYKTHPEYG KRVKYSKKYYAQDDN--NEAKVGDVVRVMETRPLSRTKRFRLLDVVEKA------------------------------- -MSRSL-KKGPFADA-HLLNKIEAQAD---SEKKQ----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVFISD-DMVGH KLGEFVPTRTFHGHG------N--DDK----KTK------AR >FIRM_Lactobacillus_salivarius_salivarius_UCC118 Concatenation of 2 sequences MGIKKFKPTTNGRRNMTGSDFAE-ITKT------------KP-EKSLLVSKSKTAGRNAYGRITVRH-RGGGHKRK---- YRLIDFK-R--VK-DNVPATVKAIEYDPNRSANIALLVYA-DGVKSYILAPKGLKVGQVVESGK-D-VD-IKVGNTLPLA NIPVGTVIHNIELKPGKGGQLVRSAGTSAQLLGK--EGKYAIIRLTSGEVRMILVTCRATIGAVGNEQHELIKVGKAGRA -RWA-----GKR-P-QSRGSVMNPNDHPHGGGEGKA-P--VGRPSPMSP---WGKKTTGLKTR-SKKARSN-K-FIVRSR --------------------------------TTK---G-ILGKKVGMTQVFT-ENGE---------LVPVTVVKVDSNV VLQVK----TME----N--DGY--EAIQLGF-------DD--LTNK----------PAKGHAK----------------- ---AN-TTPKRFVREIRD--------VELGEY-----KV---GD-EVKA--D-I-FEAGDFVDVTGTSKGHGFQGSIKRN GQHR-GPMAHGS-RYHRR-PGSMG---VIIN-RVMKGKLLPGRMGGNRVTIQNLEIVKADTENG---------------- ----------VLLIKGN-VPGANKSLVTIK-MPTVALFK-QDGNQN-GEVQLNEAIF----GI-EP-NNNVVFDAVIMQR ASLRQGTHAVKNRSA--------VR-GGGKKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- VGGGTVFGPT-P-RSYSYKLPRKVRRLAIKSVLSQKVADE----------------S-LVVVDAL----NFD-A------ --PKTKLVV--LEDDN--T---TAALAARNLKNVT-V---------------IPAKGLNVLDVINNDK----LVITQGAL SQVENRLKEKYDNEI----VPSLMEKFNYTSIMQAPKVDKIVINMGVG-DAVSNAKRLDEAVDELTLIAGQKPVITKAKK SIAGFRLREGMAIGAKVTLRGQRMYEFLDKLVSVSLPRVRDFHGVSK-RAFDGRGNYTLGIREQLIFPEID-----FDDV NKVRGMDIVIVTT-----------------------ANTDEESRELLTQLGMPFMSRIG-Y--KVVNLPEGVEVK-Q--- -D-G--N-VVTVKGPKGELTREF--SD-K--ITIKVEG-NE--VSF---ER-S--AEDNKTK-ALHGTTRSNFHNMVVGV SEGFKKELELRGVGY--RAQMKG-KT--LVLN--VGYSHPVEFEE-E-E-GITFETP--S-ATSIIVSG-INKEEVGDCA ARIRATR------APEPY---KGKGIRYVGEYVRRKEGK----------MIQQESRLKVADNSGAREILVIKILG-SRVK T--ANIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKYGTHRPDGSYIKFDENAAVIIG-EDKS-PKGTRIF GPVARELR-DGNFMKIVSLAPEVLMK-L--HELKPAEGS-RQVRNRVG-RGTSSGN-GKTAGRGQKGQKARGKV------ -RLGF-E-GGQMPLFRRMPK-RG--FKNVNLETLVTPALLVES-GIIKIK---------VLG--NGT-L-N-K-Q-LTV- KASKFSASAKEAIESKGGKA-R---EFR--GKM---RGEA-KGGKEVTFG----------KYGLKAL--DSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVLFEI--DG-- VSEEVAREALRLASHKLPVKTKF-VKNKTRQKRHARVRGKI---SGTAECPRLNVYRSNKNIYAQVIDD---V--AGVTL VSASTL-DSEV---------SGN-TKTEQASSVGAVVAKR--AVEKG-IKEVVFDRGGYLYH--GRVQALAEAARENGLD F-------------------------------------------------------------VTS-AKATAKTVRIPARK ARLVIDLIRGKSVAEAFGILKFT---------------------------------PRSGAYLIEKVLKSAVAN----A- ENNF-DLDVEDLYVSEAFVNEGPTLKRFRPRAKGSASPINKRTSHITVVVSV-MFIKKNDKVKVIAGK------DK-GKE GTVEKVFPAQD--RVI--VKGINIVKKHQK----PT--NA-NPN-GGIVEVEAPIHVSNVM-LIDPSN-------NE--A --TRVGFKV----V--------DGKVR---VSKKSG---EIL--MGQKVNPTGLRVG--II-RDWDAKWYA------E-K D--FASNLHEDLRIRKYI--ESKLA-----DASVSTVEIERAA-K-RVNISIHTAKPGMVIGKGGSEVEKLRKELNNLVH INIVEIKK---PDLDAKLVGESIAEQLENRVAFRRAMKQAIQRTMRA-GAKGIKVQVAGRLNGADMSRVERFSEGTVPL- -HTLRADIDYSWVEAHTTYGKLGVKTWIYMVMTDPIADFLTRIRNANMAKHESLEV-PASKIKRDIAEILKNEGFVRDVE YID----D---D----KQGIIRVFLKYG---KGN-------E---RVISGIRRISKPGLRSYVKADAVPKVLNGLGIAIL STSEGVITDKEARAKKIGGEVIAYIWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGATISGPIPLPTERTLYTVIRS PHKYKDSR-EQFEMRTHKRLIDIVNPTPKTVDSLMKLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVVVETYKNHKVYG KRVKYSKKFKAHDEN--NEAKVGDIVKIMETRPLSATKRFRLLEIVEKA------------------------------- -MSRSL-KKGPFVDE-HLMKKVEAQAD---QEKKS----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFVPTRTFHGHG------N--DDK----KTG------VR >FIRM_Lactococcus_lactis_cremoris_SK11 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTGSDFAE-ITTS------------TP-EKSLLVSMSKTAGRNNTGRITVRH-HGGGHKRK---- YRMIDFK-R--TT-DNVVAKVATIEYDPNRTANIALIVYA-NGVKSYILAAKGLEVGMTVVSGP-D-AD-IKVGNALPLA NIPVGTLIHNIELKPGKGGQLVRSAGASAQVLGS--EGKYTLVRLQSGEVRMILSTCRATIGVVGNEQQSLINLGKAGRT -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGRQ-P--VGRKSPMTP---WGKPALGLKTR-NKKAKSS-K-LIVRRI -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------MAKVSLFK-QDGSQA-GEVTLNDSVF----GI-EP-NESVVFDVVISQR ASLRQGTHAHKNRSA--------VS-GGGKKPW---------RQKGTGRAR--------QGS---TR-SP----QW---- RGGGTVFGPN-P-RSYAYKLPQKVRQLALKSVYSTKVADG----------------K-LIAVDTL----DFA-A------ --PKTALVV--LNEGN--E---FAELSARNLENVK-V---------------TTANSASVLDIVSADK----LLVVQSAL TQIENRLKEKYTNEV----VPALTEQFNYTSIMAVPKVDKIVINMGVG-DAVNNSKNLDKAVAELALISGQKPLITKAKK SVAAFRLREGMPIGAKVTLRGERMFEFLDKLVTVSLPRVRDFHGVSN-KAFDGRGNYTLGVKEQLIFPEIN-----YDDV DKVRGMDIVIVTT-----------------------ANTDEESRELLAKLGMPFMSRIG-N--KVIVIPAGVTVE-V--- -N-G--A-TVTVKGPKGELVRSF--NE-N--ITLEIAE-NE--ITV---KR-P--NDTKEMK-MLHGTTRALLANMVEGV SNGFSKALEMIGVGY--RAQLQG-TK--LVLS--VGKSHQDEVEA-P-E-NIKFVVA--T-PTSIVVEG-ISKEAVGQTA AYIRSRR------SPEPY---KGKGIRYVGEYVRRKEGK----------MIQTESRLKVADNSGAKELLTIRVLG-SSRK F--AGIGDIVVATVKSAAPG-G-------AVKKGEVVKAVIVRTKSGAKRPDGSYIKFDENAAVLIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLME-L--HSLKAAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKSRSGGG-V--- -RPGF-E-GGQTELFRRMPK-RG--FLNVNLETLVSAETLVAA-KIVKVK---------VLA--NGE-L-T-A-KNLTV- KVAKVSAAAKAAIEAAGGSV-R---EFR--GKM---RGYA-KGGDTVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRNGQVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GVVMFEL--GG-- VDEATAREALRLASHKLPVKTKF-VKNKLRQKRHTRVRGKI---SGTTETPRLNVFRSNTNIYAQVIDD---V--TGTTL ASASSL------K-------LTG-TKTEQAAEVGKLVAEA--AKAKG-VEEVVFDRGGYLYH--GRVAALATAAREAGLK F-------------------------------------------------------------ITS-AKATAKTVRVSPRK TRLVIDLIRGKRVADAIAILKFT---------------------------------PTKAAVEVENVLNSAIAN----A- ENNF-GLEKANLVVSETFINEGPTMKRFRPRAKGSASPINKRTAHITVVVAE-MFVKTGDTVKVIAGK------DR-GTT GKVIKALPKVN--KVV--VEGVAIMKKHQK----PN--SE-NPS-GAILEIEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DDKVR---FNKKSG---EIL--MGQKVHPIGMRVG--VI-RDWDAKWYA------E-K E--YADYLHEDLAIRQLI--QTKLA-----DASVSLIETERAI-N-KVIVTLHTAKPGMVIGKSGANVDALRAELNKLVH INIVEIKK---PDLDAHLVGEGIAKQLEARIAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNGNMRKFDVVEA-PASKIKRQIAEILKAEGYVKDVE YVE----D---N----KQGVIRVFLKYG---KNG-------E---KVITNLKRISKPGLRVYVKSDDVPKVLNGLGTAII STSTGVVTDKVARQTNVGGEVIAYIWMATKKIRIRLKAYEHRILDAAAEKIVETAKRTNAEVSGPIPLPTDRSVYTVIRA THKYKDSR-EQFEMRTHKRLIDIIEPTQKTVDSLMKLDLPSGVNIEIKLRKVYQGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NSAKTGDIVRIMETRPLSKDKRFRLVEIVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQTN---AERKS----VIKTWSRRSTIFPNFVGLTIAVYDGRKHVPVYVQE-DMVGH KLGEFAPTRTYRGHA------A--DDK----KTR------R- >FIRM_Lactococcus_lactis_lactis_Il1403 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTGSDFAE-ITTS------------TP-EKSLLVSMSKTAGRNNTGRITVRH-HGGGHKRK---- YRVIDFK-R--TT-DNVVAKVATIEYDPNRTANIALIVYS-NGVKSYILAPKGLEVGMTVVSGP-E-AD-IKVGNALPLA NIPVGTLIHNIELKPGKGGQLVRSAGASAQVLGS--EGKYTLVRLQSGEVRMILSTCRATIGVVGNEQQSLINLGKAGRT -RHM-----GIR-P-TVRGSVMNPNDHPHGGGEGRQ-P--VGRKSPMTP---WGKPALGLKTR-NKKAKSS-K-LIVRRI --------------------------------MSK---G-ILGKKVGMTQIFT-ENGE---------LIPVTVIEATPNT VLQVK----SVE----T--DGY--EATQVGF-------DT--LTNK----------PAKGHAK----------------- ---AN-TTPKRFVREFKG--------LEGAEV----------GA-EITV--D-T-FAAGDVVDVTGTSKGKGFQGPIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAAN-KVPKGKKLAGRMGNKRVTVQNLVIAQVLPEKN---------------- ----------VILVKGN-VPGAKKSLIVVK-MAKVSLFK-QDGSQA-GEVTLNDSVF----GI-EP-NESVVFDVVISQR ASLRQGTHAHKNRSA--------VS-GGGKKPW---------RQKGTGRAR--------QGS---TR-SP----QW---- RGGGTVFGPN-P-RSYAYKLPQKVRQLALKSVYSTKVADG----------------K-LIAVDTL----DFT-A------ --PKTALVV--LNEGN--E---FAELSARNLANVK-V---------------TTANSASVLDIVSADK----LLVVQSAL TQIENRLKEKYTNEV----VPALTEQFNYTSIMAVPKVDKIVINMGVG-DAVNNSKNLDKAVAELALISGQKPLITKAKK SVAAFRLREGMPIGAKVTLRGERMFEFLDKLVTVSLPRVRDFHGVSN-KAFDGRGNYTLGVKEQLIFPEIN-----YDDV DKVRGMDIVIVTT-----------------------ANTDEESRELLAKLGMPFMSRIG-N--KVIVIPAGVSVE-V--- -N-G--A-TVTVKGPKGELVRSF--NE-N--ITLDIAE-NE--ITV---KR-P--NDTKEMK-MLHGTTRALLANMVEGV STGFSKALEMIGVGY--RAQLQG-TK--LVLS--VGKSHQDEVEA-P-E-NIKFVVA--T-PTSIVVEG-ISKEAVGQTA AYIRSRR------SPEPY---KGKGIRYVGEYVRRKEGK----------MIQTESRLKVADNSGAKELLTIRVLG-SSRK F--AGIGDIVVATVKSAAPG-G-------AVKKGEVVKAVIVRTKSGAKRPDGSYIKFDENAAVLIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLME-L--HSLKAAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKSRSGGG-V--- -RPGF-E-GGQTELFRRMPK-RG--FLNVNLETLVSAETLVAA-KIIKVK---------VLA--NGE-L-TAK-K-LTV- KVAKVSAAAKAAIEAAGGSV-R---EFR--GKM---RGYA-KGGDTISFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRNGQVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GVVMFEL--GG-- VDEATAREALRLASHKLPVKTKF-VKNKLRQKRHTRVRGKI---SGTSETPRLNVFRSNTNIYAQVIDD---V--TGTTL ASASSL-KLTG-------------TKTEQAAEVGKLVAEA--AKAKG-VEEVVFDRGGYLYH--GRVAALATAAREAGLK F-------------------------------------------------------------ITS-AKATAKTVRVSPRK TRLVIDLIRGKRVADAIAILKFT---------------------------------PTKAAVEVENVLNSAIAN----A- ENNF-GLEKANLVVSETFINEGPTMKRFRPRAKGSASPINKRTAHITVVVAE-MFVKTGDTVKVIAGK------DR-GTT GKVIKALPKVN--KVV--VEGVAIMKKHQK----PN--SE-NPS-GAILEIEAPIHVSNVQ-VLDKN--------GV--A --GRVGYKV---VD--------DKKVR---FNKKSG---EIL--MGQKVHPIGMRVG--VI-RDWDAKWYA------E-K E--YSDYLHEDLAIRQLI--QTKLA-----DASVSLIETERAI-N-KVIVTLHTAKPGMVIGKSGANVDALRAELNKLVH INIVEIKK---PDLDAHLVGEGIAKQLEARIAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNGNMRKFDVVEA-PASKIKRQIAEILKAEGYVKDVE YVE----D---N----KQGVIRVFLKYG---KNG-------E---KVITNLKRISKPGLRVYVKSDDIPKVLNGLGTAII STSTGVVTDKVARETNVGGEVIAYIWMATKKIRIRLKAYEHRILDAAAEKIVETAKRTNAEVSGPIPLPTDRSVYTVIRA THKYKDSR-EQFEMRTHKRLIDIIEPTQKTVDSLMKLDLPSGVNIEIKLRKVYQGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NSAKTGDIVRIMETRPLSKDKHFRLVEIVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQVN---AERKS----VIKTWSRRSTIFPNFVGLTIAVYDGRKHVPVYVQE-DMVGH KLGEFAPTRTYRGHA------A--DDK----KTR------R- >FIRM_Leuconostoc_citreum_KM20 Concatenation of 2 sequences MAIKKYKPTSNGRRNMTASDFAE-ITKS------------TP-EKSLLAKKSKTGARNNSGRMTVRH-HAGGHKQA---- YRLVDFK-R--IK-DNTTATVKAIEYDPNRTANIALLVYE-DGIKSYILAPKGLKVGDKVQSGP-D-AD-IKVGNALPLS NIPEGTLIHNIELKPGKGGQLARSAGTSAQILGK--DGKYVIVRLTSGEVRLVLATNRATIGEVGNAEHSLINWGKAGRN -RWR-----GKR-P-HVRGSVMNPNDHPHGGGEGKA-P--VGRPSPMSP---WGKKTAGKKTR-DKKKAST-K-FIVRGR --------------------------------MTK---G-ILGRKVGMTQVFT-ESGE---------LIAVTAVEATPNV VLQVK----NIA----T--DGY--NAIQLGY-------QD--KSNK----------PEQGHAK----------------- ---AN-TTPKRYVREVRD---------AEGEF-----NA---GD-EIKV--D-T-FQAGDYVDVTGITKGHGFQGAIKKL GQSR-GPMAHGS-RYHRR-PGSMG---AIIN-RVFKGKLLPGRMGNNKRTMQNVAIVHVDVENN---------------- ----------LLLLKGN-VPGANKSLLTIK-MTKVAVLK-QDGSQA-AELELNDAVF----AI-EP-NNAVITDAVLMQR ASMRQGTHAVKNRSA--------VS-GGGRKPW---------KQKGTGRAR--------AGS---IR-EP----QF---- RGGGIVFGPT-P-RSYAYRINRKAYQLALKSVLSQKVAEG----------------K-LVVVDAL----SFE-A------ --PKTQLVV--VDEDN--E---NAILSARNLTNVQ-V---------------MTTKGINVLDVVNADK----LVIVQSSI EEIQNALKEKYVNEV----QPALIEKFNFTSPMQAPKIDKIVLNMGVG-DAVSNSKNLDEAVEELKLIAGQQPVITKAKK SIAGFRLREGMSIGTKVTLRGARMYEFLDKLINISLPRVRDFRGVSS-KAFDGRGNYTLGIREQLIFPEID-----FDQV NRVRGLDIVVVTT-----------------------AQNDEEGRELLTLLGMPFMSRIG-N--KVITLPAGVEVS-Q--- -E-G--T-VVTVKGPKGTLSREI-ASQ----ISMSVEG-TE--VAF---TR-E--SDDNKTK-ALHGTTRANVANMVEGV SEGFTKTLKLVGVGY--RAAKSG-SK--LTLS--VGYSHPVDFED-R-E-DLTVEVP--D-ALTVKVSG-ISKQRVGDLA AEIRAVR------SPEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGAREILTIKVLG-SGRK F--AGVGDMIVATVKQAIPG-G-------NVKKGDVVKAVIVRTVSDVRRADGSYINFDENAAVIVK-DDKS-PVGTRIF GPVARELR-DSDYMRIVSLAPEVLMN-L--NELQPAAGS-RKLRNRVG-RGTSSGN-GKTSGRGQKGQKARGKV------ -RLGF-E-GGQMPLYRRIPK-RG--FTNVNLEKLVTPALLIEN-GIVKIK---------VLA--VGQ-L-E-K-K-LTV- KAHKFSGAAKAAIEQAGGTT-R---VHR--GHM---RGEA-KGGKTVAFG----------EFGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKGVGVRMGNGK---------GAPEGWVEPVKR-GKVMFEV--GG-- VPEATAREALRLAQHKLPVRTKI-IKNKLRVKRHKRVRGKI---SGTAARPRLNVFRSNANIYAQLIDD---V--AGVTL ASASSH-DAEV----------SG-TKTEQATKVGELIATR--GKAAG-FEDVIFDRGGYLYH--GRVQALAESARENGLK F-------------------------------------------------------------ITS-ARATAKIVRVAPRK ARLVLDTIRRKSVNEAYAILKFL---------------------------------PNTSTEDIYKVLNSAVAN----A- ENNF-SLDREDLIVKEAFANEGPTLKRFRPRAKGSASPINKRTSHITIVVAE-MFVKTGDKVRVIAGK------DK-GKE GTITKTVAGKD--RVV--VEGVNIVKKHQK----PS--NE-YPQ-GGVIDIEAPIHVSNVQ-LLDPST-------NE--P --TKVAFKI----E--------DGKVR---VSKKSG---NVL--MGQKINPTGFRVG--VI-RDWDAKWFA------DKA D--YANQLHEDLRIRKYI--EKNLA-----DAAVDRIEIERST-KSRVDVSVHTAKPGMVIGKGGSEVEKLRTQLAKLVF INIVEIKK---PDLSAHLVGQQIAGDLERRVAFRRAMRGAIQRATRS-GAKGIKVMVSGRLNGADIARIEQYTEGTVPL- -HTLRADIDYSWDEAMTAYGNLGIKTWIYMSMTDPIADLLTRIRNANLAHHEVVEI-PASKIKKSIAEILKSEGFIRDVE YIE----D---N----KQGVIRVFLKYG---EDR-------N---RVITGIKRISKPGLRKYAKADSLPKVLNGLGIAII STSAGVITDKEARSKQVGGEVIAYVWMAQKKIRIRLKAYEHRILDQSAEKIVETAKRTGAEIAGPIPLPTERTLYTILRS PHKHKDSR-EQFEMRTHKRLIDIVNPTDKTVDALRKLELPSGVAIEIKLRKVYQGRVVSDKMDKTITVAVDTYVTHPVYG KRVKYTKKFKAHDEN--NTAKMNDIVQIMETRPLSATKHFRLVKIVEEA------------------------------- -MARSL-KKGPFADP-HLLKKIEAQAD---SEKKS----VIKTWSRRSTIFPSFIGFTIAVYDGRKHVPVFVQE-DMVGH KLGEFVPTRTFKGHK------A--DDK----KTG------KK >FIRM_Leuconostoc_mesenteroides_mesenteroides_ATCC_8293 Concatenation of 2 sequences MAIKSYKPTSAGRRNMTTSDFAE-ITKT------------TP-EKSLLAKKSKTGARNASGRMTVRH-HAGGHKQA---- YRIVDFK-R--TK-DDKTATVKAIEYDPNRTANIALLVYE-DGIKSYILAPKGLKVGDKVQSGP-D-AD-IKPGNALPLS AIPEGTLIHNIELKPGKGGQLARSAGASAQILGR--DGKYIIVRLTSGEVRLVLATNRATIGEVGNAEHSLINWGKAGRN -RWR-----GKR-P-HVRGSVMNPNDHPHGGGEGKA-P--VGRPSPMSP---WGKKTAGKKTR-DKKKAST-K-FIVRGR --------------------------------MTK---G-ILGRKVGMTQVFT-ESGE---------LIAVTAVEATPNV VLQVK----NAE----T--DGY--SAIQLGY-------QD--KSNK----------PEQGHAK----------------- ---AN-TAPKRYVREIRN---------AGDEF-----NV---GD-EIKV--D-T-FQAGEYVDVTGITKGHGFQGAIKRL GQSR-GPMTHGS-RYHRR-PGSMG---AIIN-RVFKGKLLPGRMGNNKRTMQNIAIVHVDVENN---------------- ----------LLLLKGN-VPGANKSLLTVK-MTKVAVLK-QDGSQA-AEIELNDAVF----AI-EP-NNAVITDAVLMQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------KQKGTGRAR--------AGS---IR-EP----QF---- RGGGIVFGPS-P-RSYAYRINRKAYQLALKSVLSQKVADN----------------K-LVVVDAL----SFE-A------ --PKTQLVV--VDEDN--E---NAILSARNLANVQ-V---------------MTTKGINVLDVVNADK----LVIVQSSI EEIQNALKEKYVNEV----QPALIEKFNFKSSMQAPKIDKIVLNMGVG-DAVSNSKNLDEAVEELKLIAGQQPVITKAKK SIAGFRLREGMSIGTKVTLRGERMYDFLDKLINISLPRVRDFRGVSS-KAFDGRGNYTLGIREQLIFPEID-----FDKV NRVRGLDIVIVTT-----------------------AQNDEEGRELLTQMGMPFMSRIG-N--KTITLPADVTVS-Q--- -E-G--A-VVTVKGPKGELSREI-VSA----ITMTVEG-NE--VSF---SR-D--SDDSKTR-ALHGTTRANVANMVEGV SEGFTKTLKLVGVGY--RAAKSG-SK--LTLS--VGYSHPVDFED-R-E-ELSVEVP--D-ALTIKVSG-ISKQKVGDLA AEIRAVR------SPEPY---KGKGIRYEGEVVRRKEGK----------MIQQESRLKVADNSGAREILTIKVLG-SGRK F--AGVGDMIVATVKQAIPG-G-------NVKKGDVIKAVIVRTVSDVRRADGSYINFDENAAVIVK-DDKS-PVGTRIF GPVARELR-DNDYMRIVSLAPEVLMN-L--NELQPAAGS-RHVRNRVG-RGTSSGN-GKTSGRGQKGQKARGKV------ -RLGF-E-GGQMPLYRRIPK-RG--FTNVNLNKLITPTLLIEN-GIVKIK---------ILA--VGQ-L-E-K-K-LTV- KAHKFSAAAVAAIEQAGGST-R---VHR--GHM---RGEA-KGGKTVTFG----------DFGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKGVGVRMGNGK---------GAPEGWVEPVKR-GKVMFEV--AG-- VPEATAREALRLAQHKLPVRTKI-IKNKLRVKRHKRVRGKI---SGTAARPRLNVFRSNANIYAQLIDD---V--AGVTL ASASSH-DAEV----------TG-SKTEQAVKVGELIASR--GKAAK-IEDVIFDRGGYVYH--GRVQALADSARENGLK F-------------------------------------------------------------VTS-ARATAKIVRVAPRK ARLVLDTIRRKSVNEAYAILKFL---------------------------------PNTSTEDIYKVLNSAVAN----A- ENNF-SLDREDLIVKEAFANEGPTLKRFRPRAKGSASPINKRTSHLTIVVAE-MFVKTGDKVRVIAGK------DK-GKE GTITKTVAGKD--RVV--VEGVNIVKKHQK----PS--NE-YPQ-GGVIDIEAPIHVSNVQ-LLDPST-------NE--P --TRVGFKV----E--------DGKIR---VSKKSG---NVL--MGQKINPTGFRVG--VI-RDWDAKWFA------DKA D--YANQLHEDLRIRKYI--EKNLA-----DASVDRIEIERTT-KSRVDVSIQTAKPGMVIGKGGSEVEKLRTQLAKLVF INIVEIKK---PDLSAHLVGQQIAGDLERRVAFRRAMRGAIQRATRS-GAKGIKVMVSGRLNGADIARIEQYTEGTVPL- -HTLRADIDYSWDEAMTAYGNLGIKTWIYMSMTDPIADFLTRVRNANLARHEVVEA-PASKIKKSIAEILKAEGFIRDFE YID----D---N----KQGVIRVFLKYG---EDR-------N---RVITGIQRISKPGLRKYAKAEELPKVLNGLGIAII STSAGVITDKEARSKQVGGEVIAYVWMAQKKIRIRLKAYEHRILDQSAEKIVETAKRTGAEIAGPIPLPTERTLYTILRS PHKHKDSR-EQFEMRTHKRLIDIVNPTDKTVDALRKLELPSGVAIEIKLRKVYQGRVVSDKMNKTITVAVDTYLTHDVYG KRVKYTKKFKAHDEN--NAAKQGDIVQIMETRPLSATKHFRLVKIVEEA------------------------------- -MARSL-KKGPFADP-HLLKKIEAQVD---SEKKS----VIKTWSRRSTIFPSFIGFTIAVYDGRKHVPVYVQE-DMVGH KLGEFVPTRTFKGHK------N--DDK----KTG------K- >FIRM_Listeria_innocua_Clip11262 Concatenation of 2 sequences MAIKKYKPTTNGRRHMTSSDFAE-ITTS------------TP-EKSLLRPLKKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYIIAAKGLEVGQTIYSGA-E-AD-IKVGNALELK DIPVGTVIHNIEMKPGKGGQLVRSAGTSAQVLGK--EGKYVLIRLNSGEVRMILATCRATIGQVGNEQHELINIGKAGRS -RWM-----GKR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGRKSPMSP---WGKPTLGYKTR-KKNNNSD-K-FIVRRR --------------------------------MTK---G-ILGRKVGMTQVFT-ENGE---------LIPVTVIEAAQNV VLQKK----TVE----T--DGY--EAVQIGF-------ED--KSNK----------PEQGHVK----------------- ---AD-TTPKRFIREFRD--------VNLDEY-----EI---GA-EVKV--D-V-FAEGDIIDATGVSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKLLPGRMGGEQITIQNLEIVKVDVEKN---------------- ----------VLLVKGN-VPGAKKALVQIK-MPKLSLLK-QDGTNA-GEITLNDTVF----GI-EP-NEKVVVDVILSQR ASLRQGTHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPKKVRRLAIKSILSSKVNEE----------------K-LVVLEGL----TFD-A------ --PKTKLIV--VAGES--E---NVELSARNLQGIT-V---------------IPAESISVLEVAKHDK----LIITKAAV EKVENRLKDQYLKEI----VPALMSKFNYDSVMEVPKIDKIVINTGVG-DATANAKVLDSAVEELALITGQKPVITKAKN SIAGFRLREGMPIGAKVTLRGERMYDFLDKLVTVSLPRVRDFRGVSK-KAFDGRGNYTLGVREQLIFPEID-----YDQV SKVRGMDVVIVTT-----------------------AKSDEESHELLTQLGMPFMSRIG-K--KTIVIPAGVTVT-L--- -N-G--S-TATVKGPKGELVKEF--NP-E--ITINIEG-NE--INV---SR-P--TDNKNHR-ALHGTTRAILNNMVVGV SEGYEKKLELIGVGY--RAQKQG-DK--LVLN--VGYSHPVEFVA-P-K-GVEIEVP--A-NTQVIVKG-YNKEHVGELA ANIRAVR------PPEPY---KGKGIRYEGEHVRRKEGK----------MIQQESRMKVADNSGAREVLTIKVLG-SGRK T--ANIGDVVVCTVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVLMK-L--HELKPSEGS-RKERNRVG-RGTGSGN-GKTSGRGHKGQKARSGGG-V--- -RLGF-E-GGQLPLFRRIPK-RG--FTNVNLDVLVTPELLIET-GIIRIK---------ILS--DGN-I-E-K-K-LTV- KANKFSAAAKEAIEAAGGKT-R---EFR--GNM---RGRA-KGGTEVAFG----------EYGLQAV--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKPIGVRMGKGK---------GAPEGWVSPVKR-GKIMFEI--AG-- VPEDVAREALRLAAHKLPVKTKI-VKNKVRKKRHARVRSKI---SGTESRPRLNVFRSNKNIYAQVIDD---V--NGVTL ASASNL-DKDF--------GSAE-SKVDAASKVGELVAKR--ASEKG-ITSVTFDRGGYLYH--GRVKALAEAARENGLE F-------------------------------------------------------------VTS-AKAVAKTVRIAPRK ARIVIDLIRGKQVGEAIAILKYT---------------------------------PRSASPIIEKVLKSAIAN----A- EHNY-DLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRTSHITVVVSE-MHVKKGDKVKVITGK------DK-GKS GKVLAAFPKKD--RVL--IEGINMVKKHTK----PS--NI-NPQ-GGILNVEAPIHVSNVM-LIDPKT-------GE--P --TRVGYEV---KG--------DKKVR---VAKKSG---EVI--MGQKVHPIGMRIG--VI-RDWDSKWYA------E-K D--YADFLHEDLRIRDYV--AKRLS-----DASVSRVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKNLNELVH INIVEIKR---ADLDAKLVAENIARQLEGRVSFRRAQKQAIQRTMRA-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANMVKHDKLEL-PASKIKKEIAEILKREGFIRDVE YIE----D---D----NAGTIRVFLKYG---ATG-------E---RVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIV STSQGVLTDKEARAKQVGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSIYTVLRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVVVETYKKHGLYG KRVKYSKKFKAHDEN--NIAKTGDVVRISETRPLSATKHFRLLEVVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKVEAAAE---SEKKQ----VIKTWSRRSTIFPTFVGQTIAVYDGRKHVPVYVQE-DMVGH KLGEFAPTRTYRGHA------G--DDK----KTK------R- >FIRM_Listeria_monocytogenes_EGD-e Concatenation of 2 sequences MAIKKYKPTTNGRRHMTSSDFAE-ITTS------------TP-EKSLLRPLKKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYIIAAKGLEVGQTIYSGA-E-AD-IKVGNALELK DIPVGTVIHNIEMKPGKGGQLVRSAGTSAQVLGK--EGKYVLIRLNSGEVRMILATCRATIGQVGNEQHELINIGKAGRS -RWM-----GKR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGRKSPMSP---WGKPTLGYKTR-KKNNNSD-K-FIVRRR --------------------------------MTK---G-ILGRKVGMTQVFT-ENGE---------LIPVTVIEAAQNV VLQKK----TVE----T--DGY--EAVQIGF-------ED--KSNK----------PEQGHVK----------------- ---AN-TTPKRFIREFRD--------VNLDEY-----EI---GA-EVKV--D-V-FAEGDIIDATGVSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKLLPGRMGGEQITIQNLEIVKVDVEKN---------------- ----------VLLVKGN-VPGAKKALVQIK-MPKLSLLK-QDGTNA-GEITLNDTVF----GI-EP-NEKVVVDVILSQR ASLRQGTHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPKKVRRLAIKSILSSKVNEE----------------K-LVVLEGL----TFD-A------ --PKTKLIV--VAGES--E---NVELSARNLQGIT-V---------------IPAESISVLEVAKHDK----LIITKAAV EKVENRLKDQYLKEI----VPALMSKFNYDSVMEVPKIDKIVINTGVG-DATANAKVLDSAVEELALITGQKPVITKAKN SIAGFRLREGMPIGAKVTLRGERMYDFLDKLVTVSLPRVRDFRGVSK-KAFDGRGNYTLGVREQLIFPEID-----YDQV SKVRGMDVVIVTT-----------------------AKSDEESHELLTQLGMPFMSRIG-K--KTIVIPAGVTVT-L--- -N-G--S-TATVKGPKGELVKEF--NP-E--ITIKIEG-NE--INV---SR-P--TDNKNHR-ALHGTTRAILNNMVVGV SEGYEKKLELIGVGY--RAQKQG-DK--LVLN--VGYSHPVEFVA-P-K-GVDIEVP--A-NTQVIVKG-YNKEHVGELA ANIRAVR------PPEPY---KGKGIRYEGEHVRRKEGK----------MIQQESRMKVADNSGAREVLTIKVLG-SGRK T--ANIGDVVVCTVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVLMK-L--HELKPSEGS-RKERNRVG-RGTGSGN-GKTSGRGHKGQKARSGGG-V--- -RLGF-E-GGQLPLFRRIPK-RG--FTNVNLDVLVTPELLVET-GIIRIK---------ILS--NGN-I-E-K-K-LTV- KANKFSAAAKEAIEAAGGKT-R---EFR--GNM---RGRA-KGGTEVAFG----------EYGLQAV--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKPIGVRMGKGK---------GAPEGWVSPVKR-GKIMFEI--AG-- VPEDVAREALRLAAHKLPVKTKI-VKNKVRKKRHARVRSKI---SGTESRPRLNVFRSNKNIYAQIIDD---V--NGVTL ASASNL-DKDF--------GSAE-SKVDAASKVGELVAKR--ASEKG-ITSVTFDRGGYLYH--GRVKALAEAARENGLE F-------------------------------------------------------------VTS-AKAVAKTVRIAPRK ARIVIDLIRGKQVGEAIAILKYT---------------------------------PRSASPIIEKVLKSAIAN----A- EHNY-DLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRTSHITVVVSE-MHVKKGDKVKVITGK------DK-GKS GKVLAAFPKKD--RVL--IEGINMVKKHTK----PS--NV-NPQ-GGILNVEAPIHVSNVM-LIDPKT-------GE--P --TRVGYEV---KG--------DKKVR---VAKKSG---EVI--MGQKVHPIGMRIG--VI-RDWDSKWYA------E-K D--YADFLHEDLRIRDYV--AKRLS-----DASVSRVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKNLNELVH INIVEIKR---ADLDAKLVAENIARQLEGRVSFRRAQKQAIQRTMRA-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANMVKHDKLEL-PASKIKKEIAEILKREGFIRDVE YIE----D---D----NAGTIRVFLKYG---ATG-------E---RVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIV STSQGVLTDKEARAKQVGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSIYTVLRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVVVETYKKHGLYG KRVKYSKKFKAHDEN--NIAKTGDVVRISETRPLSATKHFRLLEVVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKVEAAAE---SEKKQ----VIKTWSRRSTIFPTFVGQTIAVYDGRKHVPVYVQE-DMVGH KLGEFAPTRTYRGHA------G--DDK----KTK------R- >FIRM_Listeria_monocytogenes_HCC23 Concatenation of 2 sequences M---------------TSSDFAE-ITTS------------TP-EKSLLRPLKKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYIIAAKGLEVGQTIYSGA-E-AD-IKVGNALELK DIPVGTVIHNIEMKPGKGGQLVRSAGTSAQVLGK--EGKYVLIRLNSGEVRMILATCRATIGQVGNEQHELINIGKAGRS -RWM-----GKR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGRKSPMSP---WGKPTLGYKTR-KKNNNSD-K-FIVRRR --------------------------------MTK---G-ILGRKVGMTQVFT-ENGE---------LIPVTVIEAAQNV VLQKK----TVE----T--DGY--EAVQIGF-------ED--KSNK----------PEQGHVK----------------- ---AN-TTPKRFIREFRD--------VNLDEY-----EI---GA-EVKV--D-V-FAEGDIIDATGVSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKLLPGRMGGEQITIQNLEIVKVDVEKN---------------- ----------VLLVKGN-VPGAKKALVQIK-MPKLSLLK-QDGTNA-GEITLNDTVF----GI-EP-NEKVVVDVILSQR ASLRQGTHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPKKVRRLAIKSILSSKVNEE----------------K-LVVLEGL----TFD-A------ --PKTKLIV--VAGES--E---NVELSARNLQGIT-V---------------IPAESISVLEVAKHDK----LIITKAAV EKVENRLKDQYLKEI----VPALMSKFNYDSVMEVPKIDKIVINTGVG-DATANAKVLDSAVEELALITGQKPVITKAKN SIAGFRLREGMPIGAKVTLRGERMYDFLDKLVTVSLPRVRDFRGVSK-KAFDGRGNYTLGVREQLIFPEID-----YDQV SKVRGMDVVIVTT-----------------------AKSDEESHELLTQLGMPFMSRIG-K--KTIVIPAGVTVT-L--- -N-G--S-TATVKGPKGELVKEF--NP-E--ITIKIEG-NE--INV---SR-P--TDNKNHR-ALHGTTRAILNNMVVGV SEGYEKKLELIGVGY--RAQKQG-DK--LVLN--VGYSHPVEFVA-P-K-GVDIEVP--A-NTQVIVKG-YNKEHVGELA ANIRAVR------PPEPY---KGKGIRYEGEHVRRKEGK----------MIQQESRMKVADNSGAREVLTIKVLG-SGRK T--ANIGDVVVCTVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVLMK-L--HELKPSEGS-RKERNRVG-RGTGSGN-GKTSGRGHKGQKARSGGG-V--- -RLGF-E-GGQLPLFRRIPK-RG--FTNVNLDVLVTPELLVET-GIIRIK---------ILS--NGN-I-E-K-K-LTV- KANKFSAAAKEAIEAAGGKT-R---EFR--GNM---RGRA-KGGTEVAFG----------EYGLQAV--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKPIGVRMGKGK---------GAPEGWVSPVKR-GKIMFEI--AG-- VPEDVAREALRLAAHKLPVKTKI-VKNKVRKKRHARVRSKI---SGTESRPRLNVFRSNKNIYAQIIDD---V--NGVTL ASASNL-DKDF--------GSAE-SKVDAASKVGELVAKR--ASEKG-ITSVTFDRGGYLYH--GRVKALAEAARENGLE F-------------------------------------------------------------VTS-AKAVAKTVRIAPRK ARIVIDLIRGKQVGEAIAILKYT---------------------------------PRSASPIIEKVLKSAIAN----A- EHNY-DLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRTSHITVVVSE-MHVKKGDKVKVITGK------DK-GKS GKVLAAFPKKD--RVL--IEGINMVKKHTK----PS--NV-NPQ-GGILNVEAPIHVSNVM-LIDPKT-------GE--P --TRVGYEV---KG--------DKKVR---VAKKSG---EVI--MGQKVHPIGMRIG--VI-RDWDSKWYA------E-K D--YADFLHEDLRIRDYV--AKRLS-----DASVSRVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKNLNELVH INIVEIKR---ADLDAKLVAENIARQLEGRVSFRRAQKQAIQRTMRA-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANMVKHDKLEL-PASKIKKEIAEILKREGFIRDVE YIE----D---D----NAGTIRVFLKYG---ATG-------E---RVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIV STSQGVLTDKEARAKQVGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSIYTVLRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVVVETYKKHGLYG KRVKYSKKFKAHDEN--NIAKTGDVVRISETRPLSATKHFRLLEVVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKVEAAAE---SEKKQ----VIKTWSRRSTIFPTFVGQTIAVYDGRKHVPVYVQE-DMVGH KLGEFAPTRTYRGHA------G--DDK----KTK------R- >FIRM_Listeria_welshimeri_sv_6b_SLCC5334 Concatenation of 2 sequences MAIKKYKPTTNGRRHMTSSDFAE-ITTS------------TP-EKSLLRPLKKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYIIAAKGLEVGQTIYSGA-E-AD-IKIGNALELK DIPVGTVVHNIEMKPGKGGQLVRSAGTSAQVLGK--EGKYVLIRLNSGEVRMILATCRATIGQVGNEQHELINIGKAGRS -RWM-----GKR-P-TVRGSVMNPNDHPHGGGEGKA-P--IGRKSPMSP---WGKPTLGYKTR-KKNNNSD-K-FIVRRR --------------------------------MTK---G-ILGRKVGMTQVFT-ENGE---------LIPVTVIEAAQNV VLQKK----TVE----T--DGY--EAVQIGF-------ED--KSNK----------PEQGHVK----------------- ---AD-TTPKRFIREFRD--------VNLDEY-----EI---GA-EVKV--D-V-FAEGDIIDATGVSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKLLPGRMGGEQITIQNLEIVKVDVEKN---------------- ----------VLLVKGN-VPGAKKALVQIK-MPKLSLLK-QDGTNA-GEITLNDTVF----GI-EP-NEKVVVDVILSQR ASLRQGTHKVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPKKVRRLAIKSILSSKVNEE----------------K-LVVLEGL----TFD-A------ --PKTKLIV--VAGES--E---NVELSARNLQGIT-V---------------IPAESISVLEVAKHDK----LIITKAAV EKVENRLKDQYLKEI----VPALMSKFNYDSVMEVPKIDKIVINTGVG-DATANAKVLDSAVEELALITGQKPVITKAKN SIAGFRLREGMPIGAKVTLRGERMYDFLDKLVTVSLPRVRDFRGVSK-KAFDGRGNYTLGVREQLIFPEID-----YDQV SKVRGMDVVIVTT-----------------------AKSDEESHELLTQLGMPFMSRIG-K--KTIVIPAGVTVT-L--- -N-G--S-TATVKGPKGELVKEF--NP-E--ITINIEG-NE--INV---SR-P--TDNKNHR-ALHGTTRAILNNMVVGV SEGYEKKLELIGVGY--RAQKQG-DK--LVLN--VGYSHPVEFVA-P-K-GVEIEVP--A-NTQVIVKG-YNKEHVGELA ANIRAVR------PPEPY---KGKGIRYEGEHVRRKEGK----------MIQQESRMKVADNSGAREVLTIKVLG-SGRK T--ANIGDVVVCTVKQATPG-G-------VVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIR-DDKS-PRGTRIF GPVARELR-ENNFMKIVSLAPEVLMK-L--HELKPSEGS-RKERNRVG-RGTGSGN-GKTSGRGHKGQKARSGGG-V--- -RLGF-E-GGQLPLFRRIPK-RG--FTNVNLDVLVTPELLIES-GIIRIK---------ILS--DGN-I-E-K-K-LTV- KANKFSAAAKEAIEAAGGKT-R---EFR--GNM---RGRA-KGGTEVAFG----------EYGLQAV--EASWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTSKPIGVRMGKGK---------GAPEGWVSPVKR-GKIMFEI--AG-- VPEDVAREALRLAAHKLPVKTKI-VKNKVRKKRHARVRSKI---SGTESRPRLNVFRSNKNIYAQIIDD---V--NGVTL ASASNL-DKDF--------GSAE-SKVDAASKVGELVAKR--ASEKG-ITSVTFDRGGYLYH--GRVKALAEAARENGLE F-------------------------------------------------------------VTS-AKAVAKTVRIAPRK ARIVIDLIRGKQVGEAIAILKYT---------------------------------PRSASPIIEKVLKSAIAN----A- EHNY-DLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRTSHITVVVSE-MHVKKGDKVKVITGK------DK-GKS GKVLAAFPKKD--RVL--IEGINMVKKHTK----PS--NI-NPQ-GGILNVEAPIHVSNVM-LIDPKT-------GE--P --TRVGYEV---KG--------DKKVR---VAKKSG---EVI--MGQKVHPIGMRIG--VI-RDWDSKWYA------E-K D--YADFLHEDLRIRDYV--AKRLS-----DASVSRVEIERAA-N-RVNITIHTAKPGMVIGKGGSEVEALRKNLNELVH INIVEIKR---ADLDAKLVAENIARQLEGRVSFRRAQKQAIQRTMRA-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANMVKHDKLEL-PASKIKKEIAEILKREGFIRDVE YIE----D---D----NAGTIRVFLKYG---ATG-------E---RVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIV STSQGVLTDKEARAKQVGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSIYTVLRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVVVETYKKHGLYG KRVKYSKKFKAHDEN--NIAKTGDVVRISETRPLSATKHFRLLEVVEEA------------------------------- -MGRSL-KKGPFVDD-HLMKKVEAAAE---SEKKQ----VIKTWSRRSTIFPTFVGQTIAVYDGRKHVPVYVQE-DMVGH KLGEFAPTRTYRGHA------G--DDK----KTK------R- >FIRM_Lysinibacillus_sphaericus_C3-41 Concatenation of 2 sequences MAIKKYKPTSNGRRNMTSLDFAE-ITTN------------KP-EKSLLEPTKRKAGRNNQGKITVRH-HGGGHKKQ---- YRVIDFK-R--VK-DSIPAKVATIEYDPNRSANIALINYA-DGAKAYILAPKGLEVGQTIVSGP-D-AD-IKVGNALPLA NIPMGTTIHNIELKPGKGGQLVRSAGTSAQVLGR--EGKYVIVRLQSGEVRLVLATCRATIGQVGNEQHELVHIGKAGRS -RWL-----GKR-P-EVRGSVMNPNDHPHGGGEGRS-P--IGRKSPMTP---WGKPALGYKTR-KKKNKSD-K-FIIRGR --------------------------------MAK---G-ILGRKIGMTQVFA-ENGD---------LIPVTVIEATPNV VLQKK----TVE----T--DGY--EAIQVGF-------ED--KSNK----------PQQGHVK----------------- ---AN-TAPKRFIREFRN--------VNVEEY-----EV---GQ-EVKV--E-I-FAEGDVIDVTGVTKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMG-P-VAPN-RVFKQKKLPGQMGGNVVTIQNLEIVKVDTDRN---------------- ----------LLLVKGN-VPGSKKALVTVK-MTKVSVLS-QTGASV-GEIELNDAIF----GI-EP-NEAVLFDAVVAQR ASLRQGNHKVKNRSE--------VA-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYSYKLPKKVRRLALKSALSAKVVEQ----------------N-FLVLDAL----TLA-A------ --PKTKLFV--TADLD--E---NVALSARNIPGVT-V---------------LTANGINVLDLLGHEK----VVFTKSAV EKVESRLKEKYLNEV----SPALMSKFGYKSVMQLPKVEKIVINMGVG-DAVQNSKALDAAVEELTIITGQKPVVTKAKK SIAGFRLREGMPIGAKVTLRGERMYEFLDKLISISLPRVRDFRGVSK-KAFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------ANSDEEARELLTQFGMPFMSRVG-K--KIIEVPANVTVT-V--- -AAD--N-TVTVKGPKGELVRSF--HQ-D--MKIEQEG-NV--ISV---SR-P--SDSKEHR-TNHGTTRALLATWL--- ----------------------------LVFL------------------QVSKKL------------------------ -------------------------------------------------MILQESRMKVADNSGAREVLTIKVLG-SGRK T--ANIGDIVVCTVKKATPG-G-------VVKKGDVVKAVIVRTKSGVRRKDGTYIKFDENACVIIR-DDKS-PRGTRIF GPVARELR-DSNFMKIVSLAPEVLMK-L--HELKPAEGS-RKQRNRVG-RGIGSGN-GKTAGKGHKGQNARSGGG-V--- -RPGF-E-GGQNPLFRRLPK-RG--FTNVNLDALVTTALLLET-GLVSIK---------VLG--NGT-L-N-K-K-LTV- KAHKFSASAKEAIENAGGTT-R---EHR--GNM---RGEA-KGGKEVSFG----------EWGLQAQ--TASWITNRQIE SARIAMTRYM------KRGGKVWIKIFPHKPYTKKPLEVRMGSGK---------GSPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLASHKLPVKCKI-VKNQVRKKRHARVRSKI---SGTAERPRLNVFRSNKNIYAQLIDD---V--AGVTI VSASSQ-ENGF--------EGAG-SNVEAASKIGETIAKR--AAEKN-ITAVVFDRGGYLYH--GRVKALAEAARENGLE F-------------------------------------------------------------MTQ-AKAIARTVRIAPRK VRLVVDLIRGKQVGEAVAILRHT---------------------------------PKAASPVVEKVLKSAVAN----A- EHNY-DLDINSLVVSEVFVDEGPTLKRFRPRAQGRASAINKRTSHITLVVSE-MHVKKGDKVKVITGK------DK-GKE GVILAAFPKQD--RVL--VEGVNIVKKHVK----PN--QL-NPQ-GGIVSQEAAIHVSNVM-LIDPKS-------GE--P --TRVGYKI----E--------NGKVR---VAKKSG---AVI--MGQKVHPIGLRVG--II-RDWESKWYA------E-K D--YATLLHEDIKVRKYI--ETALK-----DASVSKVEIERAA-N-RVNITIHTAKPGKVIGKGGTEVENLRKYLSELVH INIIEIKR---ADLDARLVAENIARQLENRVSFRRAQKQAIQRTIRA-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMTDPIADMLTRIRNANMVRHEKLEV-PASNVKKEIAEILKREGFVRDVE YVE----D---N----KQGIIRIFLKYG---KDN-------E---RVITGLKRISKPGLRVYAKTNEVPKVLNGLGIALV STSQGLLTDKEARAKQVGGEVLAYVWMAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRA VHKYKDSR-EQFEMRTHKRLIDIVNPTPQTVDAL---------------------------MDKTVTVLVETHKKHKLYG KRVKYSKKFKAHDEQ--NQAKIGDIVRIMETRPLSATKRFRLVEVVEKA------------------------------- -MGRSL-KKGPFVDD-HLMKKVEVQEA---SEKKQ----VIKTWSRRSTIFPNFIGLTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHG------A--DDK----KTR------R- >FIRM_Macrococcus_caseolyticus_JCSC5402 Concatenation of 2 sequences MAIKHYKPITNGRRNMTGSDFAE-ITST------------SP-EKSLLAPLPRKAGRNNQGKLTVRH-RGGGHKRQ---- YRIIDFK-R--NK-DGIPAKVATIEYDPNRSANIALLHYL-DGEKRYIIAPKGLTVGTQVVNGP-E-AD-IKVGNCLPLQ NIPVGTVIHNIELKPGKGGQLVRSAGASAQVLGK--EGKYVLVRLKSGEVRMILSTCRATIGQVGNEQHELINIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRT-S--IGRPSPMSP---WGKPTLGKKTR-KKKNRSN-K-LIVRGR --------------------------------MTK---G-ILGRKVGMTQVFG-ENGE---------LIPVTVVEAAQNV VLQKK----TEE----V--DGY--SSIQIGF------EDKQAYATK----------PAEGHAK----------------- ---AG-TAPKRFIREFRN--------VDTEAY-----EV---GQ-EVTV--D-T-FQTGDIVDVTGVSKGKGFQGAIKRH GQSR-GPMSHGS-RYHRR-PGSMGMA-SDAS-KVFKGKALPGRMGGNTVTMQNLEIVKVDAENN---------------- ----------VILVKGN-VPGPKKGLVKIQ-MANYDVLK-VDGTKA-GSIELNDNVF----GI-EP-NQHVLFEAINLQR ASMRQGTHAVKNRSA--------VS-GGGRKPW---------KQKGTGRAR--------QGT---IR-AP----QW---- RGGGIVFGPT-P-RSYSYKMPKKMRRLALRSALSAKVQEN----------------A-FTVLESL----TFD-A------ --PKTKLFV--VEAED--V---NVALSARNIPGVT-V---------------ITTTGLNVLDIVHANQ----VVMTKGAV EKVETRLKEKFLNEI----TPEMMKKFEYSSIMEVPKIEKIVVNMGIG-DAVQNSKVLDSAVEELQAITGQKPMVTKAKK SIATFRLREGMPIGAKVTLRGERMYEFFDKLVNVSLPRVRDFRGISN-KAFDGRGNYTLGVKEQLIFPEID-----YDKV SKTRGMDIVIVTT-----------------------ANTDEEARELLTQFGMPFMSRVG-K--KIIDIPSGVEIK-I--- -D-G--N-TVTVKGPKGELTRTF--NE-E--LTYKLED-NT--LEV---VR-P--SDSKAHK-TIHGTTRALIANMVEGV SKGFEKNLELIGVGY--RAQMQG-KN--LILN--VGYSHPIEIVA-E-E-GITLSVD--K-NTKVKVEG-ISKERVGAIA SNIRATR------PPEPY---KGKGVRYEGEYVRRKEGK----------MIQQESRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKNATPG-G-------VVKKGEVVKAVIVRTKSGVRRNDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HEMKPVEGA-RKERNRVG-RGMASGN-GKTSGRGHKGQKARSGGG-V--- -RLGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLITPASLIET-GVVSIK---------VLG--NGE-L-S-K-K-LTV- KAHKFSASAKEAIEGKGGTT-R---QHR--PKT---TGRS-KGGNEVTFG----------EYGLQAT--TAAWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGSGK---------GAVEGWVAVVKP-GRIMFEI--AG-- VPEEVAREALRLASHKLPVKTKF-VKNKVRMKRHARVRSKL---AGTTERPRLNVYRSNKHIYAQVIDD---V--KGVTL AQASTQ-DKNL---GL----ETT-SNVEAAAKVGEAVAKL--AVEKG-VKAVVFDRGGYLFH--GRVKALADAARENGLE F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKEVAEAIAILKLT---------------------------------NKASSPVVEKLLMSALAN----A- EHNY-DMNIDSLVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVAD-MHIKKGDKVIVITGK------DK-GKT GTVIEALPKRD--RVV--VEGVNIVKKHQK----PT--QM-NPE-GGITEFEAAIHVSNVM-LLDPKT-------NK--P --TRVGTKI----E--------DGKVR---VAKKSG---EII--MGQKINPIGLRVG--II-RDWDAKWFA------E-K D--FATLLHEDLKVRKYI--EENLK-----DASVSRVEIERAA-N-RVNIAIHTGKPGMVIGKGGSEIEKLRNNLNSLVH INVVEVKK---VDMDARLVAENIARQLENRVSFRRAQKQAIQRAMKL-GAKGIKTQVSGRLGGADIARAEQYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMSDPIADMLTRVRNANMVRHEKLEL-PASNIKKEIAEILKREGFVKSVE YIE----D---D----KQGVIRMFLKYG---ANN-------E---RVITGLKRISKPGLRVYAKADELPKVLNGLGIALV STSEGVLTDKEARQRNIGGEVLAYIWMAKQKIRIRLKAYDHRIIDQSAEKIVETAKRSGAEVSGPIPLPTEKTVYTIIRA VHKYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYTGKVVSDKMDKTITVVVETYKTHSLYG KRVKYSKKYKAHDEN--NTAKMGDIVKIMETRPLSATKRFRLVEVVEES------------------------------- -MARSL-KKGPFIDD-HLMKKVEALEE---GGKKT----VIKTWSRRSTIFPNFIGHTIAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTYKGHG------A--DDK----KTK------R- >FIRM_Moorella_thermoacetica_ATCC_39073 Concatenation of 2 sequences MAIKKFKPTSPGRRQMTVSTFAE-ITAT------------EP-YKPLVEPLKKTGGRNNQGRLTVRH-RGGGHKRL---- YRVIDFK-R--DK-DGIPGRVATIEYDPNRSANIALINYA-DGEKRYILAPENLQVGDQVISGP-E-AD-IKVGNALPLS QIPVGTMVHNVELKPGKGGQMARSAGAGAQLMAK--EGGYALLRLPSGEVRKVQESCRATVGQVGNLDWENINIGKAGRK -RWL-----GIR-P-TVRGVVMNPVDHPHGGGEGRA-P--VGRKHPVTP---WGKPAMGAKTR-KKRKLSD-K-LIVKPR --------------------------------MRK---G-ILGKKIGMTQVFD-ETGR---------AIPVTVIQAGPCV VIRKK----ETS----T--DGY--DAVQVGF-------EP--VVNK----------PLLGYFK----------------- ---AG-VTPFRYIREFRL--------ENSGEY-----QV---GQ-EIKA--D-V-FSPGEKVDVTGISKGKGFAGGIKRH GFHR-GPMEHGS-KYHRR-PGSLAA--KGPA-RVFKGRRLPGHLGAVRVTVQGLEVVRNDPERN---------------- ----------LLLIKGS-VPGPRHGLLVIK-MPRVALYN-IQGQQV-GEVDLDDSVF----GG-EV-NEAVLHDAVVMQL ASRRRGTAATRGWAD--------VS-GGGRKPW---------RQKGTGRAR--------AGS---IR-SP----LW---- RGGAVIFGPQ-P-RDYGYRLPKKVRRLALRSALASKVRDG----------------N-IIVLDEL----KME-K------ --PRTKLVV--TATRE--P---NVELSARNLPGVR-F---------------LTSDGINVYDLLAHDK----LVITKDAV ARVQARLKEKYLQEI----RKALQAKFGYKNIMEIPKLEKIVINMGVS-EATQNPKAIDNAVQDLMTITGQKPVVTKAKK SIAAFKLRQGTSIGCKVTLRGDRMYEFLDRLINVALPRVRDFHGVSP-NSFDGRGNYTLGIREQLIFPEIE-----YDKI DKVRGMDIVMVTT-----------------------AKSDEEARELLRGFGMPFMSRIG-K--KPVKIPAGVEVN-I--- -E-G--N-TVTVKGPKGKLTRQF--PA-E--ITISREG-EE--LQV---SR-P--SDAKPHR-ALHGLSRALLQNMVDGV TRGFEKGLELVGVGY--RAAKQG-NK--LVLS--VGYSHPVEMV--PGE-GLEIEVP--A-PNKVIVKG-IDKEAVGALA AKIRDVR------PPEPY---KGKGIKYEGEYIRRKVGK----------MIQQQTLLKVGDNTGARKLMCIRVLG-SKRR Y--ASVGDVIIASVKEATPG-G-------VVKKGDVVRAVVVRTKKAVKRPDGSYIRFNENAAVIIN-EQNN-PRGTRIF GPVARELR-EKDFMKIISLAPEVLMR-L--HELHPAPGS-RPRATRVG-RGIGSGL-GKTSGRGHKGQKARSGGG-V--- -RRGF-E-GGQMPLTRRLPK-RG--FTNINVGELVTPELLHDA-GLVKVK---------ILG--DGE-L-T-K-K-LTV- KVQAASRKAIEKIEAAGGKV-K---PHR--PGT---QGKA-TRGNEVTFG----------DYGLQAL--EPAWITSRQIE ASRIAMTRYI------KRGGKVWIKIFPDTPITAKPAETRMGSGK---------GAPEYWVAVVKP-GRILFEM--AG-- VSEEVAREAMRLAAHKLPIKTKF-VRKLARQRKHLRVRRRL---MGTPERPRLSVYRSLRHIYAQVIDD---T--RGVTL VAASTL-DPAL-KGL-----EST-GNITAARKVGELIARK--ALAKG-INKVVFDRGGNIYH--GRIAAVAEGAREAGLN F--------------------------------------------------------------ME-AKAVARYIRISPRR VRQVIDLIRGKGVREAEAILMVT---------------------------------PKRGSRVVAKVLKSAVAN----A- EHNY-DLDASNLVVSRAYVDEGPTLKRYQPRAMGRANIRRKRTSHITVVVGERVHVKKGDTVMVITGK------DA-GKK GKVLSVEPARG--RVV--VEGVNIVKRHTR----PT--QK-MPQ-GGIIEKEAPVASSNVM-LFCNKC-------NR--P --TRIGRQI---LA--------DGKTR---VCKKCG---EVI--MGQKVHPKGLRLG--II-RDWDSRWYA------G-K E--YKTLLHEDLKIREFI--KKRLY-----QAGIASVEIERAA-N-RIKVIVNTAKPGIVIGRGGAEVEALRKDLERLVN LNIAEIKK---PELNAQLVAENVAAQLEKRIAFRRAMKQAVGRAMRL-GAQGIKIACGGRLAGAEIARTEWYSEGKVPL- -HTLRADIDYGFAEANTTYGKIGVKVWIY--MTDPIADFLTRIRNANMVYQEKVEV-PASRVKRALAEILKNEGYIKNYE YIE----D---N----KQGILRLYLKYG---PNK-------E---KVITGLKRISCPGLRVYAKKGEIPRVLGGLGVAVI STSKGILTDKEARRQGVGGEVICYIWMARQKIRIRLKAFDHRVLDQSSQKIVDTARRTGAVVSGPIPLPTEKNIFTILRS PHVNKDSR-EQFEMRTHKRLIDILEPTPKTVDALMRLDLPAGVDIEIKLRKTRVGSVVSDKMDKTVVVAVEDRVRHPLLN KIIRHTRKFKAHDEK--NECRIGDKVRIMETRPLSKEKRWRVVEIMERA------------------------------- -MGRSL-KKGPYCDA-KLLKKIIDMNE---KGEKR----VIKTWSRRSTIFPEMVGHTIAVHDGRKHVPIYITE-DMVGH KLGEFAPTRVFRGHG------A-HTER----STA------LK >FIRM_Natranaerobius_thermophilus_JW/NM-WN-LF Concatenation of 2 sequences VSIKKFKPTSPGKRYMTVASKEE-ITRE------------EP-EKSLLAPLKNKSGRNNQGRISTRR-QGGRHKRK---- YRIIDWK-R--DK-DGVPAKVASIEYDPNRTAYIALLNYV-DGEKRYILAPLGIKPGDKIESGS-K-AE-IRPGNALPIR NIPVGTIVHNVELKPEKGGQLARSAGTYCQIVAK--EGKYAHVKLPSEEVRMIHLDCRATVGQVGNVEHENIDLGKAGRA -RWQ-----GKR-P-SVRGVAMNAVDHPHGGGEGKA-F--VGRKTQYTP---WGQKSAGYKTR-RKAKKSD-K-YIVKKR --------------------------------MKK---A-ILGKKVGMTQIFS-EEGE---------VMPVTVVKAGPCS VVQKK----VED----T--DGY--NAVQIGF-------ED--KTKK----------PEKGHFK----------------- ---AG-VNPKKHLTEFEL--------ESMENL-----EV---GQ-ELTV--E-Q-FEVGDQIDVTGTSKSKGFQGTIKRF KHST-GPKTHGS-RFYRA-PGSLGS--MDIS-RVFKGQTLPGRMGGNTVTVQRLEVVDVDKENN---------------- ----------LLLVKGA-VPGPKKGLLKIV-MPKVALYN-NEGSQV-GEITLDDSIF----AT-DI-NETLMHEAVNMHL ASKRRGTASAKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------HGS---IR-SP----IW---- VGGGISFAPK-P-RDYSYKMPKKAKRKAIKSALTTKLNNG----------------E-IVILEEL----TME-A------ --PKTKMIV--TGASD--L---NVYRSTRNIPGVS-S---------------ALANNLNVYDVLNHDY----LVLTKDAV SVIEARLLEHYRGEV----KPKLKDEMGYKNIMEVPKLEKVVVNMGIG-DAKDNPKILDNAVENLEQVTGQKPVVTKAKR SIANFKVRQGMPVGCKVTLRGERMYHFLDKLINVALPRVRDFKGVSP-KAFDGRGNYSLGLKEQMVFPELE-----YDDI ERVQGMDIIIATT-----------------------AETDEEAKKLLERLGMPFMSRIG-K--KPIEIPDSVDIS-I--- -N-N--N-EVTVKGPKGELSQVV--DQ-S--IILEEEE-GQ--LLV---KR-P--TDSNHHK-SLHGLSRSLIANMVEGV TNGFERHLEIVGVGY--RAQMQG-KN--LVLN--VGYSHPVTIEP-P-E-GVEIEVP--K-NNQIIVKG-TDKEVVGQVA ARIRAVR------KPEPY---KGKGIKYAEEQIIRKVGK----------MIQTESTLRVADNTGAREIQCIKVIA-GQKQ Y--ANVGDVIVGTIKEATPG-G-------VVKRGQVVRAVIVRTKRGIKRPDGSYIRFDENACVIID-ENKD-PRGTRIF GPVTRELR-EKKYMKIISLAPEVLMR-L--HELRPKTNY-KKSRKRKG-RGMSSGL-GKTAGRGHKGQNARTGGG-V--- -RPGF-E-GGQMPLQERLPK-RG--FTNVNVETLITPEVLLES-KVIKIK---------VLG--KGE-I-D-K-K-ITV- KAHKFSKQAKEKIEEAGGKV-R---QMR--GRM---KGKA-KGGKEIAFG----------EFGLQAL--EPAWINSRQIE AARIALTRYI------KRGGKVWVKIFPDKPVTQKPAETRMGGGK---------GSPEFWAAVVKP-GRILFEV--AG-- VPKETAREAMRLASHKLPIKTKF-VRKQARKKRHRRVRKKI---YGTSERPRLNVYRSAKNIHAQVIDD---N--RGHTL VHASTL-DPEI-KDDY----QGK-NNQEASAAVGRLIAKR--SKDKG-IEDVIFDRGGYLYH--GRVKALAEAAREEGLN F--------------------------------------------------------------ME-AKATARYVRISPRK AREVIDMIRGKNIEEALGILQLT---------------------------------PKGATKPIEKVVKSAQAN----A- ENNF-EMNPDSLYISECYVDEGPTLKRFRPRAMGRATPINKKTSHLTVVVKEKLHVKSGDTVVVISGK------DK-GKR GKVLRTFPSEQ--KVL--VEGVNMINKHTR----AT--QE-NPQ-GGIVEQEGPVYADKVM-VYCSKC-------QK--P --VRTGAKI---DD--------KGKSR---ICKKCG---VEL--MGQKINPIGLRIG--VI-KDWQSNWYA------D-K N--YTELVHEDIKIREYI--ENKLF-----NADVSAIQIDRAA-N-RIKVTLHTAKPGMVIGKGGSGVEKLRSDIENLVH INVMEVKT---PELDAHLAAKSIAIALERRVAFRRAMKQAVGRAMRQ-GAKGIKVMCSGRLGGAEMSRTEWYTEGNVPL- -QTLRADIDYGMVEANTAYGQIGVKCWINMTMTDPIADMLTRIRNAQSVYHKQVEI-PASKLKRELVDILKREGYINDFE YID----D---N----KQGILRIELKYS---DND-------E---QVISGLKRISKPGLRVYAKKDEIPRVLGGLGIAVV STSSGLLTDREARDQGIGGEILCYIWANKQKIRIRLKAFDHMILDQSAEKIVETAKRTGANVSGPVPLPTDKNVYTVIRA PHKFKDSR-EQFEMRTHKRLIDILDPTSKTVDSLMRLDLPSGVDIEIKLRKVRTGRVVSDKMDKTRVVLVEGRTKHPLYE KTVKQAKKFKAHDEA--NETREGDVVKIMETRPTSKDKRWRIVDIIERT------------------------------- -MPRSI-KKGPFVDD-HLLKKVKEMNK---SNKKQ----VIKTWSRRSTILPDMIGHTIAVHDGRKHVPVFITE-DMVGH KLGEFAPTRTFRGHG------D-HTER----STS--LK---- >FIRM_Oceanobacillus_iheyensis_HTE831 Concatenation of 2 sequences MAIKKFKPTSNGRRNMSVSDFAE-ITTD------------TP-EKSLLSPIRKRGGRNNQGKLTVRH-QGGGHKRQ---- YRIIDFK-R--DK-DGIPGRVATIEYDPNRSANIALVHYA-DGEKRYIIAPKGIKVGQEIESGE-N-AD-IKLGNALPLG SIPVGTVIHNIELKPGRGGQIARSAGAEAQILGR--EEKYTLVRLSSGEVRLILTTCRATIGQVGNIEHELVRVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRKSPMSP---WGKPTLGYKTR-QRNKPSD-K-YIVRKR --------------------------------MTK---G-ILGRKIGMTQLFS-DNGE---------LIPVTVIQAEPNV VLQKK----TLE----N--DGY--EALQIGF-------AD--KTNK----------AEKGHAK----------------- ---AG-TAPKRYVREIRG--------AEVNSF-----EV---GQ-EIKV--D-I-FESGEKIDVTGTSKGKGFQGVIKRH GQQR-GPTTHGS-HFHRA-PGAMGV--IDPM-RVFKGKKLPGHMGSEQVTIQNLEVVSVDTDKN---------------- ----------LLLIKGN-VPGAKKSYVKIT-MPKVALLK-QDGSNV-GDIELNDSVF----GI-EP-NTHVLHEAVVMQR ASLRQGTHAVKNRSE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---TR-SP----QW---- VGGGTVFGPT-P-RSYSYKLPKKVRRLALRSALSSKVNEE----------------S-LLVLENI----SID-A------ --PKTKLIV--LSEKD--E---TVIRSANNLQNVT-V---------------LTVEELNILDLLMHDK----LIITKDAA EKAGNELKQKYQDEI----VSSLMDKFNYNSVMEVPKVEKIVINMGVG-DAVQNSKALDSAVEELSLISGQKPMITRAKK SIAGFRLREGMPIGAKVTLRGERMYEFLQKLVAVSLPRVRDFRGISK-KAFDGRGNYTLGVKEQLIFPEIN-----YDKV SKIRGMDIVVVTT-----------------------SNTDEEARELLAQLGMPFMSRVG-L--KPVEIPEGVELK-L--- -D-N--N-TVTVKGPKGELSREL--HP-D--MKINIED-NV--LTV---ER-P--SDHKEHR-ALHGTTRSLINNMVIGV SKGFEKSLEIIGVGY--RAQKQG-DK--TVIN--AGYSHPVELEA-I-D-GIEIEVP--K-NTQITVKG-IDKELVGAIA ANIRAIR------PPEPY---KGKGIRYTDEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKQATPG-G-------VVKKGEVVKAVIVRSKSGARRKDGSYIRFDENAAVIIR-DDKS-PRGTRIF GPVARELR-DAQFMKIVSLAPEVLMK-L--HELKAAEGT-RKERNRVG-RGMSSGN-GKTSGRGHKGQKARSGGG-V--- -RPGF-E-GGQMPLFQRLPK-RG--FTNVNLDTLITPELLLET-GVVSIK---------ILG--KGT-L-E-K-K-LTV- KAHKFSASAKEAIETAGGQS-R---QHR--GKM---RGQA-KGGTTVAFG----------EYGLQAT--EASWITSRQIE AARIAMTRYM------KRGGKVWIKIFPDKPYTAKPLEVRMGSGK---------GAPEGWVAVVKP-GKIMFEI--AG-- VSEEVAREALRLASHKLPVKTKF-VKNVIRKKRHNRVRRTL---SGTAERPRLNVYRSNKNIYAQLIDD---N--AGVTV ASASTA-DKEL--------AIGG-GNVESAKQVGAAIAKR--AIDKG-YKSIVFDRGGYLYH--GRIKALAEAAREEGLE F--------------------------------------------------------------MQ-AKAVAKSVRIAPRK VRLVVDLIRGKEVGEAIAILNHT---------------------------------QRGASPVVEKVLKSAIAN----A- EHNY-EMDADSLVISEAFVNEGATLKRFRPRAQGRASRINKRTSHITVVVTE-MHVKKGDKVKVLSGK------DR-GKE GTVLEAFPKNE--RVL--VEGVNMVQKHAK----PS--QE-NPQ-GGILNIEAPIHVSNVL-PVDPKS-------GE--P --TRVGYEV----K--------DGKIR---IAKKSG---EAL--MGQKINPTGLRVG--II-KDWESKWYA------G-K D--YADLLHEDIKIREYL--ENRLS-----TAAVSSIEIERAA-N-RVNITIHTGKPGMVIGKGGSEVEALRKSLNNLVH INIVEIKK---VDLDATLVADSIARQLENRISFRRAQKQAIQRAMRG-GAKGIKTQVSGRLGGADIARAEHYSEGTVPL- -HTLRADIDYGTAEADTTYGKLGVKVWIYMVMTDPIADMLTRIRNANMVKHEKLEL-PASNIKKEIADILKREGFVKDYE LIE----D---N----KQGVLRIFLKYS---ANE-------D---KVISGIKRISKPGLRVYAKADEVPRVLNGLGIAIV STSNGLLSDKEARSQAVGGEVLAYVWMAKEKIRIRLKAYDHRILDQSAEKIVDTAKRSGAKVSGPIPLPTEKSVYTVLRA VHKYKDSR-EQFEMRTHKRLIDILEPTPKTVDALMRLDLPSGVDIEIKLRKVYTGRVVSDKMDKTITVLVETYKFHKLYG KRVKYSKKFKTHDEN--NVAKNGDVVRIMETRPLSATKRFRLVEVTEEA------------------------------- -MGRSL-KKGPFADD-HLMKKIEVLNT---DDKKQ----VIKTWSRRSTIFPTFVGHTVAVYDGRKHVPVYITE-DMVGH KLGEFAPTRTYRGHA------G--DDK----KTK------R- >FIRM_Oenococcus_oeni_PSU-1 Concatenation of 2 sequences MAIKTYKPTTNGRRNMSGFDFSV-ITKT------------TP-EKSLLAKKSKTGARNAEGRMTVRH-HGGGHKQQ---- YRIIDFK-R--IK-DDKTATVKAIEYDPNRTANIALLVYE-DGVKSYILAPKGLEAGTKVQSGP-D-AD-IKVGNALPLG NIPEGTLIHNIELKPGKGGQLARSAGTSAQILGK--DGKYVIIRLSSGEVRMIPATSRATIGEVGNAEHSLISWGKAGRS -RWR-----GKT-P-HVRGSVMNPNDHPHGGGEGKA-P--VGHPSPMSP---WGKKSYGKKTR-DKKKPST-K-FIVRGR --------------------------------MTK---G-ILGRKVGMTQVFT-DKGE---------LIPVTVIEALPNV VLQVK----TPE----T--DGY--SALQLGV-------FD--KANK----------PEQGHAK----------------- ---AS-AAPKRYVREIRD---------AQGDY-----KQ---GD-KVKV--D-V-FAAGEYVDVQGITKGHGFQGSIKRL GQSR-GPMAHGS-RYHRR-PGSMG---SIIN-KVFKGKLLPGQMGGDLRTAQKLLVAGVDPANN---------------- ----------LILIKGN-VPGANKSFVTIK-MTKVALYK-QDGTQA-GEVELADSIF----AI-EP-NEAVVTDAVLMQR ASLRQGTHSVKNRST--------VS-GGGRKPW---------RQKGTGNAR--------QGS---IR-AP----QW---- RGGAISMGPI-P-RPYAYKINRKAYRLALKSVLSDKVSAK----------------N-FVIIDEL----NFE-K------ --PSTKLLV--VDDAN--E---NAKLSARNLPNVQ-V---------------TTASGVNVYDLVKAQK----VVIVQSAV KQVENALKEKYVNEV----RPALISKFDYTSLMQAPKLEKIVLNMGVG-DAVTNSNNLDEAVSELRLIAGQQPVVTKAKK SIAGFRLREGMSIGSKVTLRGTRMYDFLDKLINVALPRVRDFHGTST-KSFDGRGNYTLGIKEQLIFPEIN-----YDDV NRVRGLDIVIVTT-----------------------AKTDEEGLELLSQLGMPFMSRIG-N--KAITIPTGVEIK-Q--- -E-G--D-QVTVKGPKGEITRSI--AS-V--ISMNIEG-SE--AKF---SR-P--DDSNRNK-ALHGTTRANVANMIEGV SKGFKKNLELVGVGY--RASMQG-DK--LVLT--VGFSHPVEFEA-R-E-GLKVAVP--D-ATHISIEG-ISKQRVGDFA AEIRGVR------PPEPY---KGKGIRYQGEIVRRKEGK----------MIQQESRLKVADNSGAREILTIKVLG-SGRK F--ANIGDMIVATVKQAIPG-G-------TVKKGDVVKAVIVRTVSGVHRIDGSYIKFDENAAVIVR-DDKS-PVGTRIF GPVARELR-DNNYMRIVSLAPEVLMD-L--STLKPVAGS-RKSSTRKA-RGFSAGK-GKTAGRGQKGQKAREGKK-L--- -RLSF-E-GGQMPLMRRMPK-RG--FNNVNLDQLVSASSLKEA-GIIKVK---------VLA--SGK-L-N-K-K-ITI- HAAKASQAAQDSIKEAGSKI-R---VHR--GHM---RGEA-KGGRTVAFG----------DYGLQSL--ENNWITNRQIE AARIAITRYM------KRGGKVWIKIFPQKSYTSKGVGVRMGNGK---------GAPEGWVAPTKR-GTIMFEV--GG-- VSEAVAKEALRLAMHKLPVKAKI-VKNKTRQKRHARVRGKI---SGTAQRPRLSVFRSNSNIYAQVIDD---V--AGVTL ASASTL-EKEN---------QGG-TKSEQASKVGQSVAKL--AIAKK-ITEVVFDRSGYLYH--GRVRSLADGAREAGLK F-------------------------------------------------------------VTS-AKATAFQVRIAPRK ARLVLDTVRGKSVNEAYAILKFL---------------------------------PNTGTEPVYKVLNSAVAN----A- ENNF-ALDRADLVIKEAYANEGPTMKRFRPRAKGTASKINKRTSHITIVVSE-MNIKTGDKVRVIAGK------DK-GKE GSVTKVFLKTD--RVI--VEGVNKVKKHQK----PT--QA-EPK-GGIIEKEAAIHVSNVM-LLDASK-------KK--- ------------------------TIR---ASKRES---NKK--MGQKINPIGFRVG--VI-RDWDAKWYA----D-K-K E--YVPALQEDLRIRKYL--ETNLK-----DAAVDRITIERTE-PTRINLTIHTAKPGIVIGRGGADVERLRSELSKIVN INIVEIRK---PDLNAHLVGQQIAADLERRVAFRRAMRGAIQRVQRA-GAKGVRTMVSGRLNGADIARKEQYTEGTVPL- -HTLRADIDYSWDEAMTSYGNLGIKTWIYMTMSDPIADFLTRIRNANMVRHETVET-PASKIKINIAQILKDEGFITDYQ VVD----T--PN----KQGLISLSLKYG---PNR-------E---RIITGLKRISKPGLRSYVQADSVPKVLNGLGIAIL STSEGVMTDKAARAKMIGGEVIAYVWMAERKIRIRLKAYEYRTIDASAAKIVETAKRTGAQVVGPIPLPTERTIYTILRS PHKHKDSR-EQFEMRTHKRLIDLVNPTDKTVDSLRKLDLPAGVAIEIKLRKVYRGRVVSDKMDKTITVAVETYKNHPVYG KRVNYAKKFKAHDEN--NDAKLNDVVEIMETRPLSATKRFRLVRVVEKA------------------------------- -MSRSL-KKGPFADP-SLLKKIEQLKG---QSKKP----VIRTWSRRSTIFPSFIGFTIAVYDGRKHVPVYIQD-DMVGH KLGEFVPTRTFRGHA------GSDDKK----TGK-------- >FIRM_Pediococcus_pentosaceus_ATCC_25745 Concatenation of 2 sequences MGIKKFKPTTNARRGMTQLDYSE-ITKK------------SP-EKSLLESQSHTAGRNNYGRMTVRH-RGGGNKRQ---- YRIIDFK-R--IK-DDVPATVKAIEYDPNRTANIALLVYA-DGVKSYIIAPKGLKVGDKVQSGS-E-AD-IKVGNALPLK DIPVGTVIHNIELKPGKGGQLVRSAGASAQLLGK--EGKYVLIRLASSEVRMVLATNRATIGAVGNEEHELVNVGKAGRT -RYA-----GQR-P-HVRGSVMNPNDHPHGGGEGKA-P--IGRPSPLSP---WGKKTIGKKTR-NKHNKSN-K-FIVRGR --------------------------------TTK---G-ILGKKVGMTQVFT-EAGE---------LIPVTVIDTTPNV VLQLK----TVE----N--DGY--SSVQLGF-------DD--KSNK----------PEQGHVK----------------- ---AN-TNPKRFIHEIRN--------VELGDV-----KV---GD-TIAA--D-I-FEAGEIVDVTGTTKGHGFQGVIKKD GQRR-GPMAHGS-RYHRR-PGSLG---AVIN-RVFPGKKLPGRMGNKTVTIQHLEIVKADTENN---------------- ----------VLLVKGN-VPGAKKSYLVVK-MANVSLFK-QDGTKN-GDVELNADIF----GI-EP-NNDVVFEAVVMQR ASMRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYAYSIPKKMRRLALKSVLSQKVLDE----------------S-LVVVDEF----KFE-T------ --PKTKLLV--LEEDN--E---SAVLAARNLSNVK-I---------------VEPEGINVLDIMNSDK----LVITQKAL SQVENRLKEKFVNEI----TPDLVKKFDYTSVMQVPKIEKIVLNMGVG-DAVTNSKNLDEAVAELELISGQKPLVTKAKK SIAGFRLREGMSIGAKVTLRGERMYDFLDKLVNVSLPRVRDFRGVSS-KAFDGRGNYTLGVREQLIFPEID-----FDNV NRVRGLDIVIVTT-----------------------ANTDEESRELLAQFGMPFMSRIG-R--KPVEIPAGVEIK-Q--- -D-G--N-VVTVKGPKGELTRTM--SS-D--ITMSVDG-NV--VSF---DR-P--NDNNKMR-ALHGTTRANFNNMVEGV VNGFEKKLELIGVGY--RAQLKG-KT--LILN--LGYSNPVEMET-P-E-DLKVEVP--D-NTHINISG-ISKQRVGDLA AEIRAVR------SPEPY---KGKGVRYVGEYVRRKEGK----------MIQQESRLKVADNSGARELLVIKVLG-SRVK F--GYIGDIIVATVKQATPG-G-------VVKKGDVVKAVVVRTKQGAHRADGSYIKFDENAAVLIK-DDKS-PQGTRIF GPVARELR-DKDYMKIVSLAPEVLMK-L--NELMPSEGS-RTNRKRIG-RGTSSGT-GKTAGRGQKGQKARGKV------ -RLGF-E-GGQMPLYRRIPK-RG--FTNVNLDALVTPESLLKA-GIISVK---------VLG--NGE-I-T-K-K-LTV- KANKFSESAVKAIEAAGGKT-R---EHR--GRM---RGAA-KGGKTVAFG----------EYGLQAL--TSSWITNRQIE AARVAMTRYM------KRGGKVWIKIFPHKSYTSKGVGVRMGNGK---------GTPEGWVAPVKR-EKVMFEV--AG-- VPEEVAREALRLAAMKLPVKTKI-IKNKKRQRRHARVRSKI---SGTAECPRLNVYRSNKNIYAQVIDD---V--AGVTL VSASTL-DSEI---------SGG-SKTELASQVGALVAKR--AVEKK-IENVVFDRGGYIYH--GRVQALAEAARENGLK F-------------------------------------------------------------VTS-AQATAKTVRIAARK IRLVVDLIRGKSVAEAFAILKFT---------------------------------PRSASPVVEKVLKSAVAN----A- ENNF-DLDREDLVISKVFVNEGPTLKRFRPRAKGSASPINKRTSHITVVVSE-MFVKVGDKVRVISGK------DK-GKE GTIKQTLAKKN--RVV--VEGLNMIKKHQK----PN--NA-NPQ-GGILDVEAPMDVSNVM-LIDPST-------NE--P --TRVGFKT----V--------DGKVR---VSKKSG---ESI--MGQKVNPNGFRVG--VI-RDWQAKWYA------D-K D--FSKFLAEDIKIREFI--AKQLT-----DASVSTVEIERAA-N-RVNISIHTAKPGMVIGKGGSEVEKLRNQLNQLVH INIVEIKK---PDLEAKLVGENIAAQLEGRVAFRRAMKQAMQRSMRS-GAKGIKTQVAGRLNGADMSRVERYSEGKVPL- -HTLRADVDYAWVEARTTYGQLGVKTWIYMSMTDPIADFLTRIRNANMVRHESLEV-PASKIKKDMAEILKNEGFIKDVE YIE----D---D----KQGIIRVFLKYG---KNN-------E---RVISGLKRISKPGLRSYVKSDEVPKVLNGLGIAII STSEGVITDKEARAKKIGGEVLAYIWMAKQKIRIRLKAYEHRILDQSADKIVETAKRTGATISGPIPLPTERTVYTVLSS PHKFKKAR-EQFEMRTHKRLIDIVNPTPKTVDSLMKLDLPSGVDIEIKLRKVYQGRVVSDKMDKTITVQIDTYKTHPVYG KRVKYSKKYKAHDEN--NAAKMGDIVTIMETRPLSATKRFRLLDIVEKA------------------------------- -MGRSL-KKGPFADE-HLLKKVDAQKD---QDKKP----VIKTWSRRSTIFPSFIGCTIAVYDGRKHVPVYIQD-DMVGH KLGEFVPTRTFRGHG------G--DDK----KTS------GK >FIRM_Pelotomaculum_thermopropionicum_SI Concatenation of 2 sequences MAIKKFKPTSPGRRFVTVSDFEE-ITRT------------EP-EKSLVEPLKKSGGRNAQGRITVRH-RGGGHKRL---- YRIIDFK-R--DK-DGIPAKVASIEYDPNRSARIALLHYA-DGEKRYIIAPAGLEVGQTVVSGP-D-AD-IKAGNCLPLK NIPVGTMIHNIELYPNGGGKLVRSAGASAQLMAK--EGKYANIRMPSGEMRLLLQECRATIGQVGNVEHENITIGKAGRK -RWL-----GIR-P-TVRGVVMNPVDHPHGGGEGRS-P--IGRN-PVTP---WGKPALGARTR-KKKP-GD-R-LIVKRR --------------------------------MPK---G-LLGKKVGMTQIFT-DTGL---------AVPVTVIEAGPCI VVQKK----TPE----K--DGY--SAIQLGF-------GA--KFNK----------PMLGHF------------------ ---AARVRPLRYLREVRV--------ENPETY-----QV---GQ-EIKA--D-I-FAPGEKVDVVGTTKGRGFAGGIKRH GFHR-GPMAHGS-KYHRR-PGSLG-A-KGPA-RVFKGRRLPGHLGMERVTVQNLEVVKVDADRN---------------- ----------LLAVKGA-VPGPKGGLVLIK-MPTVALYN-TNGEQV-GELALKDEIF----GV-EV-HEPVLHDAVVMHL ANRRLGTHDTKTRSE--------VR-GGGRKPW---------RQKGTGRAR--------HGS---IR-SP----LW---- RGGGIIFGPH-P-RDYSYSLPRKVRRLALKSALSAKVNSG----------------D-ILVLDEL----KLD-Q------ --PKTKLLV--TAEKD--E---AVERSARNIPNIK-P---------------VQAALLNVYDILAYDK----LVMTRDAV ARVEARLKDKYKNEV----VPAMMQKFGYKNPMQVPRLEKVVVNMGLG-EAIQNSKIIDAAVNDLMTITGQRPVVTKAKR SIAAFKLRAGMSIGAKVTLRGERMYEFVDKLINVALPRVRDFRGISP-KSFDGRGNYSLGVREQLIFPEIE-----YDKI DKVRGMDIIFVTT-----------------------AKTDEEARELLKLMGMPFMSRIG-R--QPITVPAGVEVE-I--- -D-G--S-TVKVKGPKGQLVKEM--HR-D--MIIKYED-GR--LIV---ER-P--ANDKLHK-SLHGLTRTLLNNMVVGV TAGFQKNLELVGVGY--RASKQG-NK--LVLA--VGYSHPVEIE--P-EAGLEIEVP--A-PTKISIKG-VDKEKVGALA AAIRAVR------QPEPY---KGKGIKYEGEKIRRKVGK----------MIQVQSILNVADNTGARRLMCIRVLG-ALRR Y--ASVGDIIVCSVKEATPG-G-------VVKKGDVVRAVVVRTKKEVRRPDGSYIKFDENAAVIIK-DDKS-PRGTRIF GPVARELR-DRDFMKIVSLAPEVIMK-L--HELKPAPGA-RTKPTRRG-QGIGSGM-GKTAGRGHKGQKARSGGG-V--- -RPGF-E-GGQMPLQRRMPK-RG--FTNVNIEKLVTPEALLAA-RVIKVK---------ILG--NGN-L-E-K-S-LTV- QAHAFSSTARQKIEAAGGRA-K---QHR--GRP---GGGMAKGGKEINFG----------EYGLMAL--EPAWITNRQIE AARIAMTRHI------KRGGKVWIRIFPDKPITAKPAETRMGSGK---------GTPEYWVAVVKP-GRIMFEL--AG-- VTEEVAREAMRLASHKLPIKTKF-VRNALRDKRRRRVRKKI---RGTAERPRLNVFRSLQNIYAQIIDD---D--RGVTL VSASTL-APEL-KGKL----PSG-GNTAAAAAVGELLAKK--AIEAG-IKRVVFDRAGYVYH--GRVKALAEAARAGGLE F--------------------------------------------------------------ME-AKAVARYIRISPRK VRQVVDLIRGKKLNEALAILRYT---------------------------------PKRASAVVAKVVRSAAAN----A- ENNL-QMDRDELFIKACYVDQGPTYKRYMPRAFGRADVMRKRTSHITVVVSDKVHVRKGDTVLVITGK------NA-GKK GKVISVIPAKS--RVV--VEGVNVVKRHTK----PT--RK-MPQ-GGIVEKEAPIHSSNVM-LFCGKC-------NS--P --TRVGKKF---LE--------DGKVR---VCKRCG---ETI--MGQKVNPKGLRIG--II-RDWEGKWYA------DKR N--YAALLHEDIKIRKFI--KEKLF-----AAGISRIQIERAA-N-RVKVSIHTAKPGIVIGRGGAEVENLRKQLENLVS VNIVEIKV---PELDAQLVAENVAAQLEKRIAFRRAMKQVVSRSMKM-GAKGIKVACGGRLAGAEIARTEWYSEGKVPL- -HTLRADIDYGFAEANTTYGKIGVKVWIYMVMTDPIADFLTRIRNANTVYHEKVEA-PASKVKKAIANILKDEGFVKDCE FID----D---G----KQGIIRIYLKYG---PNK-------E---RVITGLKRISKPGLRVYARKDQVPKVLGGLGIAII STSKGIMTDKKARKEGLGGEVICYVWMKSQKIRIRLKAFDHHMLDQSAQKIVETARRTGASVAGPVPLPTEKSIYTILRS PHVNKDSR-EQFEMRTHKRLIDILEPNPKTVDALMRLDLPAGVDIEIKLRKTLTGRVVSNKMDKTVVVAVETLVRHPLYQ RTIRRTKKFKAHDEE--NACRIGDKVKMMETRPLSKEKRWRVVEILERT------------------------------- -MSRSL-KKGPYCDA-RLLAKIEKMNE---TGEKR----VIKTWSRASTIFPQMVGHTIAVHDGRKHVPVYITE-DMVGH KLGEFAPTRIFRGHG------A-HTER----STA------LK >FIRM_Staphylococcus_aureus_aureus_COL Concatenation of 2 sequences MAIKKYKPITNGRRNMTSLDFAE-ITKT------------TP-EKSLLKPLPKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGINAKVDSIQYDPNRSANIALVVYA-DGEKRYIIAPKGLEVGQIVESGA-E-AD-IKVGNALPLQ NIPVGTVVHNIELKPGKGGQIARSAGASAQVLGK--EGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR -----------------------------------------------MTQVFG-ENGE---------LIPVTVVEAKENV VLQKK----TVE----V--DGY--NAIQVGF-------ED--KANK----------PAEGHAK----------------- ---AD-AAPKRFIREFRN--------VDVDAY-----EV---GQ-EVSV--D-T-FVAGDVIDVTGVSKGKGFQGAIKRH GQSR-GPMSHGS-HFHRA-PGSVGMA-SDAS-RVFKGQKMPGRMGGNTVTVQNLEVVQVDTENK---------------- ----------VILVKGN-VPGPKKGLVEIR-MANYDVLK-LDGTKS-GSIELSDAVF----GI-EP-NNSVLFEAINLQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------KQKGTGRAR--------QGT---IR-AP----QW---- RGGGIVFGPT-P-RSYAYKMPKKMRRLALRSALSFKAQEN----------------G-LTVVDAF----NFE-A------ --PKTKLVV--TENED--V---NVELSARNIPGVQ-V---------------TTAQGLNVLDITNADS----LVITEAAA KKVENRLKEKFNTEV----TENLMKKFNYSSVMEVPKIDKIVVNMGVG-DAVQNSKVLDNAVEELELITGQKPLVTKAKK SIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSK-KAFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------ANTDEEARELLANFGMPFMSRVG-K--KIIDIPSDVTVT-F--- -D-G--N-HVTVKGPKGELSRTL--NE-R--MTFKQEE-NT--IEV---VR-P--SDSKEDR-TNHGTTRALLNNMVQGV SQGYVKVLELVGVGY--RAQMQG-KD--LILN--VGYSHPVEIKA-E-E-NITFSVE--K-NTVVKVEG-ISKEQVGALA SNIRSVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKNATPG-G-------VVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKPAEGS-RKERNRVG-RGVATGN-GKTSGRGHKGQKARSGGG-V--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLVTPALLVES-GVVKIK---------ILG--NGS-L-D-K-K-LTV- KAHKFSASAAEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNYVTFG----------EFGLQAT--TTSWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGAGK---------GAVEGWIAVVKP-GRILFEV--AG-- VSEEVAREALRLASHKLPVKTKF-VKNKVRLKRHARVRTNL---SGTAEKPRLNVYRSNKHIYAQIIDD---N--KGVTL AQASSK-DSDI--------ATTA-TKVELATKVGEAIAKK--AADKG-IKEIVFDRGGYLYH--GRVKALAEAARESGLE F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKNAAEAIAILKLT---------------------------------NKASSPVIEKVLMSALAN----A- EHNY-DMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVKVIAGK------DK-GKE GKVIATLPKKD--RVV--VEGVNIMKKHQK----PT--QL-NPE-GGILETEAAIHVSNVQ-LLDPKT-------NE--P --TRVGYKF----V--------DGKVR---IAKKSG---EEI--MGQKINPIGLRVG--II-RDWEAKWYA------E-K D--FASLLHEDLKIRKFI--DNELK-----EASVSHVEIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNALVH INVIEIKK---VDLDARLVAENIARQLENRASFRRVQKQAITRAMKL-GAKGIKTQISGRLGGADIARAEQYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMTDPIADMLTRVRNANMVRHEKLEL-PASNIKKEIAEILKSEGFIKNVE YVE----D---D----KQGVLRLFLKYG---QND-------E---RVITGLKRISKPGLRVYAKASEMPKVLNGLGIALV STSEGVITDKEARKRNVGGEIIAYVWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRA VHMYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGKVVSDKMDKTITVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDIVKIQETRPLSATKRFRLVEIVEES------------------------------- -MARSI-KKGPFVDE-HLMKKVEAQEG---SEKKQ----VIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTFKGHV------A--DDK----KTR------R- >FIRM_Staphylococcus_aureus_aureus_N315 Concatenation of 2 sequences MAIKKYKPITNGRRNMTSLDFAE-ITKT------------TP-EKSLLKPLPKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGINAKVDSIQYDPNRSANIALVVYA-DGEKRYIIAPKGLEVGQIVESGA-E-AD-IKVGNALPLQ NIPVGTVVHNIELKPGKGGQIARSAGASAQVLGK--EGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR --------------------------------MTK---G-ILGRKIGMTQVFG-ENGE---------LIPVTVVEAKENV VLQKK----TVE----V--DGY--NAIQVGFEDKKAYKKDAKSANK----------PAEGHAK----------------- ---AD-AAPKRFIREFRN--------VDVDAY-----EV---GQ-EVSV--D-T-FVAGDVIDVTGVSKGKGFQGAIKRH GQSR-GPMSHGS-HFHRA-PGSVGMA-SDAS-RVFKGQKMPGRMGGNTVTVQNLEVVQVDTENK---------------- ----------VILVKGN-VPGPKKGLVEIR-MANYDVLK-LDGTKS-GSIELSDAVF----GI-EP-NNSVLFEAINLQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------KQKGTGRAR--------QGT---IR-AP----QW---- RGGGIVFGPT-P-RSYAYKMPKKMRRLALRSALSFKAQEN----------------G-LTVVDAF----NFE-A------ --PKTKLVV--TENED--V---NVELSARNIPGVQ-V---------------TTAQGLNVLDITNADS----LVITEAAA KKVENRLKEKFNTEV----TENLMKKFNYSSVMEVPKIDKIVVNMGVG-DAVQNSKVLDNAVEELELITGQKPLVTKAKK SIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSK-KAFDGRGNYTLGVKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------ANTDEEARELLANFGMPFMSRVG-K--KIIDIPSDVTVT-F--- -D-G--N-HVTVKGPKGELSRTL--NE-R--MTFKQEE-NT--IEV---VR-P--SDSKEDR-TNHGTTRALLNNMVQGV SQGYVKVLELVGVGY--RAQMQG-KD--LILN--VGYSHPVEIKA-E-E-NITFSVE--K-NTVVKVEG-ISKEQVGALA SNIRSVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKNATPG-G-------VVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKPAEGS-RKERNRVG-RGVATGN-GKTSGRGHKGQKARSGGG-V--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLVTPALLVES-GVVKIK---------ILG--NGS-L-D-K-K-LTV- KAHKFSASAAEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNYVTFG----------EFGLQAT--TTSWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGAGK---------GAVEGWIAVVKP-GRILFEV--AG-- VSEEVAREALRLASHKLPVKTKF-VKNKVRLKRHARVRTNL---SGTAEKPRLNVYRSNKHIYAQIIDD---N--KGVTL AQASSK-DSDI-ATTA--------TKVELATKVGEAIAKK--AADKG-IKEIVFDRGGYLYH--GRVKALAEAARESGLE F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKNAAEAIAILKLT---------------------------------NKASSPVIEKVLMSALAN----A- EHNY-DMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVKVIAGK------DK-GKE GKVIATLPKKD--RVV--VEGVNIMKKHQK----PT--QL-NPE-GGILETEAAIHVSNVQ-LLDPKT-------NE--P --TRVGYKF----V--------DGKVR---IAKKSG---EEI--MGQKINPIGLRVG--II-RDWEAKWYA------E-K D--FASLLHEDLKIRKFI--DNELK-----EASVSHVEIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNALVH INVIEIKK---VDLDARLVAENIARQLENRASFRRVQKQAITRAMKL-GAKGIKTQVSGRLGGADIARAEQYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMTDPIADMLTRVRNANMVRHEKLEL-PASNIKKEIAEILKSEGFIKNVE YVE----D---D----KQGVLRLFLKYG---QND-------E---RVITGLKRISKPGLRVYAKASEMPKVLNGLGIALV STSEGVITDKEARKRNVGGEIIAYVWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRA VHKYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGKVVSDKMDKTITVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDIVKIQETRPLSATKRFRIVEIVEES------------------------------- -MARSI-KKGPFVDE-HLMKKVEAQEG---SEKKQ----VIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTFKGHV------A--DDK----KTR-------R >FIRM_Staphylococcus_carnosus_carnosus_TM300 Concatenation of 2 sequences MALKHYKPITNGRRNMTSLDFAE-ITKT------------TP-EKSLLQPLPKRAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIPAKVDSIQYDPNRSANIALLVYA-DGEKRYIIAPKGLQVGQTIENGE-E-AD-IKTGNALPLA NIPVGTTIHNIELKPGRGGQIARSAGASAQVLGK--EGKYVLVRLRSGEVRMILSTCRATVGQVGNLQHELVNVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR --------------------------------MTK---G-ILGRKIGMTQVFG-ENGD---------LIPVTVVEAGQNV VLQKK----TEE----V--DGY--NAIQVGF-------ED--KANK----------PAEGHAK----------------- ---AG-TAPKRFIREFKN--------INVDEY-----EV---GQ-EVSV--D-T-FEAGDIIDVTGVSKGKGFQGNIKRH GHAR-GPMAHGS-HFHRA-PGSVGMA-SDAS-KVFKGHKMPGRMGGNTVTVQNLEVVQIDAENN---------------- ----------VILVKGN-VPGPKKGLVEIK-MANYDVLK-VDGSKA-GSVELSDSVF----AI-EP-NKDVIFEAINLQR ASLRQGTHSVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- RGGGIVFGPT-P-RSYSYKMPKKMRRLALRSALSFKVQEN----------------G-FTVVDAF----GLE-A------ --PKTKLVV--TESED--V---NVELSARNIPGVQ-I---------------TTVTGLNVLDITSADS----VLITEAAA KKVESRLKEKFNTEV----TENLMKEFNYSSVMEVPKIDKIVVNMGVG-DAVQNSKVLDNAVEELELITGQKPLITKAKK SVATFRLREGMPIGAKVTLRGDRMYEFLDKLIAVSLPRVRDFHGVSK-KAFDGRGNYTLGIKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------ANTDEEGRELLKQFGMPFMSRVG-K--KIIEIPSDVTVD-I--- -K-G--N-VITVKGPKGELTRTF--DD-S--MSYKLED-NT--LEV---VR-P--SDSQKDR-TVHGTTRALINNMVQGV SKGFEKTLELIGVGY--RAQLQG-SN--LVLN--VGYSHPVEFK--P-EDGITFTVE--K-NTTVKVEG-ISKELVGATA SNIRAVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKNATPG-G-------VVKKGEVVKAVVVRTKSGVRRKDGSYIKFDENACVVIR-DDKS-PRGTRIF GPVARELR-DNNYMKIISLAPEVLMK-L--HELYPAEGS-RKVRNRVG-RGAATGN-GKTSGRGQKGQKARSGGK-V--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLEQLVTPELLIET-GVVKIK---------VLG--NGS-L-E-K-K-LTV- KAHNFSASAAEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNFVTFG----------EYGLQAI--TTSWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGAGK---------GAVEGWIAVVKP-GRILFEV--AG-- VSEEVAREALRLASHKLPVKTKF-VKNKVRLKRHARVRSNL---SGTAQKPRLNVYRSNKHIYAQIIDD---T--KGVTL VQASTQ-DKDF-------ENETG-SKVELSSKVGEAIAKK--AADKG-ITEIVFDRGGYLYH--GRVKALADAARENGLQ F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKNVGEAIAILKLT---------------------------------NKASSPVVEKLLMSALAN----A- EHNY-DMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVIVISGK------DK-GKT GVVQSTEPKKD--RVV--VEGVNIIKKHQK----PT--QF-NPE-GGILETEAPIHVSNVQ-LLDPKT-------NE--P --TRVGYKF----V--------DGKIR---IAKKSG---EEI--MGQKINPIGLRVG--II-RDWDAKWYA------E-K D--FSTLLHEDLKIRKFI--DNELK-----EASVSNVEIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNKLVH INVIEIKK---VDLDARLVAENIARQLENRASFRRVQKQAISRAMKL-GALGVKTQVSGRLGGADIARAERYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMSDPIADMLTRVRNANMVRHEKIEL-PASNIKKQIAEILKSEGFIKNVE FVE----D---D----KQGVLRLFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKADEVPKVLNGLGIALV STSEGIVTDREARKRNVGGEVLAYVWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGAEVSGPIPLPTEKSVYTIIRA VHKYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGRVVSDKMDKTITVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDIVKIQETRPLSATKRFRLVEIVEES------------------------------- -MARSI-KKGPFVDN-HLMKKVEAQEG---NQKKT----VIKTWSRRSTIFPNFIGITFAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTFKGHA------V--DDK----KTR------R- >FIRM_Staphylococcus_epidermidis_ATCC_12228 Concatenation of 2 sequences MALKKYKPITNGRRNMTTLDFAE-ITKT------------TP-EKSLLQPLPKRAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIIAKVDSIQYDPNRSANIALLVYA-DGEKRYIIAPKGLQVGQTVESGA-E-AD-IKVGNALPLQ NIPVGTVIHNIELKPGKGGQLARSAGASSQVLGK--EGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRS -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR --------------------------------MTK---G-ILGRKIGMTQVFG-ENGE---------LIPVTVVEASQNV VLQKK----TEE----V--DGY--NAIQVGF-------ED--KANK----------PAEGHAK----------------- ---AD-TAPKRFIREFRN--------VNVDEY-----EL---GQ-EVSV--D-T-FETGDIIDVTGVSKGKGFQGAIKRH GQGR-GPMAHGS-HFHRA-PGSVGMA-SDAS-KVFKGQKMPGRMGGNTVTVQNLEVVQVDTENS---------------- ----------VILVKGN-VPGPKKGLVEIT-MANYDVLK-VDGSKS-GSVELNDAVF----AI-EP-NNSVLFEAINLQR ASLRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- RGGGVVFGPT-P-RSYAYKMPKKMRRLALRSALSFKVQEN----------------S-FTIVDTF----GFE-A------ --PKTKLVV--TENED--V---NVELSARNIPGVQ-V---------------TTAQGLNVLDLTSADS----VIITEAAA KKVENRLKEKFNTEV----TENLVKKFNYSSVMEVPKIEKIVVNMGVG-DAVQNSKVLDNAVEELELITGQKPLVTKAKK SVATFRLREGMPIGAKVTLRGERMYEFLDKLIAVSLPRVRDFQGVSK-TAFDGRGNYTLGVKEQLIFPEID-----YDKV TKVRGMDIVIVTT-----------------------ANTDEEARELLTNFGMPFMSRVG-K--KIIDIPSDVTVT-F--- -D-G--S-HVTVKGPKGELERTL--NE-R--MTFKQEE-NT--VEV---VR-P--SDSKEDR-TDHGTTRALLNNMVLGV SQGYEKTLELVGVGY--RAQMQG-KD--LVLN--VGYSHPVEIKA-E-E-GITFAVE--K-NTTVKVSG-VSKEQVGAIA SNIRSVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDIIVCTVKNATPG-G-------VVKKGDVVKAVVVRTKSGVRREDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKAAEGS-RRVRNRVG-RGAATGN-GKTSGRGQKGQKARSGGK-V--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLVTPALLVES-GVVKIK---------VLG--NGS-L-D-K-K-LTV- KAHKFSASAAEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNYVTFG----------EYGLQAT--TTSWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGAGK---------GAVEGWIAVVKP-GRILFEV--AG-- VPEEVAREALRLASHKLPVKSKF-VKNKVRLKRHARVRTKL---SGTAEKPRLNVYRSNKHIYAQIIDD---V--KGVTL AQASSQ-DKDI-------ANTSA-SKVDLATTVGQEIAKK--ANDKG-IKEIVFDRGGYLYH--GRVKALADAARENGLE F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKNAGEAIAILKLT---------------------------------NKASSPVIEKVLMSALAN----A- EHNY-DMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVKVIAGK------DK-GKE GKVVATEPKKD--RVV--VEGVNVIKKHQK----PT--QL-NPE-GGILETEAAIHVSNVQ-LLDPKT-------NE--P --TRVGYKT----V--------DGKVR---IAKKSG---EEI--MGQKINPIGLRVG--VI-RDWEAKWYA------E-K D--FASLLHEDLKIRKFI--DNELK-----EASVSHVDIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNTLVH INVIEIKK---IDIDARLVAENIARQLENRASFRRVQKQAITRAMKN-GAKGIKTQVSGRLGGADIARAEQYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMTDPIADMLTRVRNANMVRHEKLEL-PASNIKKEIAEILKSEGFIKNVE YVE----D---D----KQGVIRLFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKANEVPKVLNGLGIALV STSEGVITDKEARKRNVGGEIIAYVWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRA VHKYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGRVVSDKMDKTVTVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDIVKIQETRPLSATKRFRLVEIVEES------------------------------- -MARSI-KKGPFVDD-HLMKKVEAQDG---SEKKQ----VIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTFKGHA------A--DDK----KTR------R- >FIRM_Staphylococcus_epidermidis_RP62A Concatenation of 2 sequences MALKKYKPITNGRRNMTTLDFAE-ITKT------------TP-EKSLLQPLPKRAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGIIAKVDSIQYDPNRSANIALLVYA-DGEKRYIIAPKGLQVGQTVESGA-E-AD-IKVGNALPLQ NIPVGTVIHNIELKPGKGGQLARSAGASSQVLGK--EGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRS -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR --------------------------------MTK---G-ILGRKIGMTQVFG-ENGE---------LIPVTVVEASQNV VLQKK----TEE----V--DGY--NAIQVGF-------ED--KANK----------PAEGHAK----------------- ---AD-TAPKRFIREFRN--------LNVDEY-----EV---GQ-EVSV--D-T-FETGDIIDVTGVSKGKGFQGAIKRH GQGR-GPMAHGS-HFHRA-PGSVGMA-SDAS-KVFKGQKMPGRMGGNTVTVQNLEVVQVDTENS---------------- ----------VILVKGN-VPGPKKGLVEIT-MANYDVLK-VDGSKS-GSVELNDAVF----AI-EP-NNSVLFEAINLQR ASLRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- RGGGVVFGPT-P-RSYAYKMPKKMRRLALRSALSFKVQEN----------------S-FTIVDTF----GFE-A------ --PKTKLVV--TENED--V---NVELSARNIPGVQ-V---------------TTAQGLNVLDLTSADS----VIITEAAA KKVENRLKEKFNTEV----TENLVKKFNYSSVMEVPKIEKIVVNMGVG-DAVQNSKVLDNAVEELELITGQKPLVTKAKK SVATFRLREGMPIGAKVTLRGERMYEFLDKLIAVSLPRVRDFQGVSK-TAFDGRGNYTLGVKEQLIFPEID-----YDKV TKVRGMDIVIVTT-----------------------ANTDEEARELLTNFGMPFMSRVG-K--KIIDIPSDVTVT-F--- -D-G--S-HVTVKGPKGELERTL--NE-R--MTFKQEE-NT--VEV---VR-P--SDSKEDR-TDHGTTRALLNNMVLGV SQGYEKTLELVGVGY--RAQMQG-KD--LVLN--VGYSHPVEIKA-E-E-GITFAVE--K-NTTVKVSG-VSKEQVGAIA SNIRSVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDIIVCTVKNATPG-G-------VVKKGDVVKAVVVRTKSGVRREDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKAAEGS-RRVRNRVG-RGAATGN-GKTSGRGQKGQKARSGGK-L--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLVTPALLVES-GVVKIK---------VLG--NGS-L-D-K-K-LTV- KAHKFSASAAEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNYVTFG----------EYGLQAT--TTSWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGAGK---------GAVEGWIAVVKP-GRILFEV--AG-- VPEEVAREALRLASHKLPVKSKF-VKNKVRLKRHARVRTKL---SGTAEKPRLNVYRSNKHIYAQIIDD---V--KGVTL AQASSQ-DKDI-------ANTSA-SKVDLATTVGQEIAKK--ANDKG-IKEIVFDRGGYLYH--GRVKALADAARENGLE F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKNAGEAIAILKLT---------------------------------NKASSPVIEKVLMSALAN----A- EHNY-DMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVKVIAGK------DK-GKE GKVVATEPKKD--RVV--VEGVNVIKKHQK----PT--QL-NPE-GGILETEAAIHVSNVQ-LLDPKT-------NE--P --TRVGYKT----V--------DGKVR---IAKKSG---EEI--MGQKINPIGLRVG--VI-RDWEAKWYA------E-K D--FASLLHEDLKIRKFI--DNELK-----EASVSHVDIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNTLVH INVIEIKK---IDIDARLVAENIARQLENRASFRRVQKQAITRAMKN-GAKGIKTQVSGRLGGADIARAEQYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMTDPIADMLTRVRNANMVRHEKLEL-PASNIKKEIAEILKSEGFIKNVE YVE----D---D----KQGVIRLFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKANEVPKVLNGLGIALV STSEGVITDKEARKRNVGGEIIAYVWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRA VHKYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGRVVSDKMDKTVTVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDIVKIQETRPLSATKRFRLVEIVEES------------------------------- -MARSI-KKGPFVDD-HLMKKVEAQDG---SEKKQ----VIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTFKGHA------A--DDK----KTR-------R >FIRM_Staphylococcus_haemolyticus_JCSC1435 Concatenation of 2 sequences MALKKYKPITNGRRNMTSLDFAE-ITKS------------TP-EKSLLQPLPKKAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGITAKVDSIQYDPNRSANIALLVYA-DGEKRYIIAPKGLQVGQVVESGA-D-AD-IKVGNALPLQ NIPVGTVIHNIELKPGKGGQLARSAGASSQVLGK--EGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR --------------------------------MTK---G-ILGRKIGMTQVFG-ENGE---------LIPVTVVEASQNV VLQKK----TEE----V--DGY--NAIQVGF-------ED--KANK----------PAEGHAK----------------- ---AG-AAPKRFIREFRN--------VNVDEY-----EV---GQ-EVTV--D-T-FEAGDIIDVTGTSKGKGFQGAIKRH GQAR-GPMAHGS-HFHRA-PGSVGMA-SDAS-RVFKGQKMPGRMGGNTVTVQNLEVVQVDTENN---------------- ----------VILVKGN-VPGPKKGFVEIQ-MANYDVLK-VDGSKS-GSVELSDSVF----AI-EP-NNSVLFEAINLQR ASLRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- RGGGIVFGPT-P-RSYAYKMPKKMRRLALRSALSFKVKEN----------------N-FTIVDNF----GFE-A------ --PKTKLVV--TDSED--V---NVELSARNIPGVQ-V---------------STAQGLNVLDITSADS----VIITESAA KKVENRLKERYNTEV----TENLVKKFNYSSVMEVPKIEKIVVNMGVG-DAVQNSKVLDNAVEELELITGQKPLVTKAKK SVATFRLREGMPIGAKVTLRGERMYEFLDKLIAVSLPRVRDFQGVSK-TAFDGRGNYTLGIKEQLIFPEID-----YDKV SKVRGMDIVIVTT-----------------------ANTDEEARELLTNFGMPFMSRVG-K--KIIDIPSDVTVT-F--- -D-G--H-TATVKGPKGELTRTF--NE-R--MTFKQEE-NT--IEV---VR-P--TESKEDR-TVHGTTRALLNNMVQGV SQGFEKTLELVGVGY--RAQMQG-SD--LVLN--VGYSHPVEIKA-E-D-GITFAVE--K-NTTVRVSG-VSKEQVGAIA SNIRSVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVCTVKNATPG-G-------VVKKGDVVKAVVVRTKSGVRRNDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKAAEGS-RRVRNRVG-RGAGSGN-GKTSGRGQKGQKARSGGG-V--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLVTPALLVET-GVVKIK---------VLG--NGS-L-D-K-K-LTV- KAHKFSASAVEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNYVTFG----------EYGLQAT--TTSWITSRQIE SARIAMTRYM------KRGGKVWIKIFPHTPYTKKPLEVRMGAGK---------GAVEGWIAVVKP-GRILFEV--AG-- VSEEVAREALRLASHKLPVKTKF-VKNKVRLKRHARVRTKL---SGTAEKPRLNVYRSNKHIYAQIIDD---V--KGETL VQASSK-DKDI-------ASDST-SKVDLSTKVGEAIAKK--ASDKG-IKEIVFDRGGYLYH--GRVKALAEAARESGLE F--------------------------------------------------------------ME-AKAVARTIRIAPRK VRLVLDLIRGKNAGEAIAILKLT---------------------------------NKASSPVIEKVLMSALAN----A- EHNY-DMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVKVIAGK------DK-GKE GKVIATEPKKD--RVV--VEGVNVIKKHQK----PT--QL-NPE-GGILETEAAIHVSNVQ-LLDPKT-------NE--P --TRVGYKF----V--------DGKVR---IVKKSG---EEI--MGQKINPIGLRVG--II-RDWEAKWYA------E-K D--FASLLHEDLRIRKFI--DNELK-----EASVSHVEIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNNLVH INVIEIKK---IDIDARLVAENIARQLENRASFRRVQKQAISRAMKL-GAKGIKTQVSGRLGGADIARAEQYSEGTVPL- -HTLRADIDYAHAEADTTYGKLGVKVWIYMTMTDPIADMLTRVRNANMVRHEKLEL-PASNIKKQIAEILKSEGFIKNVE YVE----D---D----KQGVIRLFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKANEVPKVLNGLGIALV STSEGVITDKEARKRNVGGEIIAYVWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGAEVSGPIPLPTEKSVYTIIRA VHMYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGKVVSDKMDKTITVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDIVKIQETRPLSASKRFRLVEIVEES------------------------------- -MARSI-KKGPFVDD-HLMKKVEAQDG---SEKKQ----VIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTE-DMVGH KLGEFAPTRTFKGHA------A--DDK----KTR------R- >FIRM_Staphylococcus_saprophyticus_saprophyticus_ATCC_15305 Concatenation of 2 sequences MALKKYKPITNGRRNMTSLDFAE-ITKT------------TP-EKSLLQPLPKRAGRNNQGKLTVRH-HGGGHKRQ---- YRVIDFK-R--NK-DGINAKVDSIQYDPNRSANIALLVYA-DGEKRYIIAPKNLKVGQVLESGE-E-AD-IKVGNALPLQ FIPVGTVIHNIELKPGKGGQIARSAGASAQVLGK--EGKYVLIRLRSGEVRMILSTCRATIGQVGNIQHELVNVGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGRA-P--IGRPSPMSP---WGKPTLGKKTR-RGKKSSD-K-LIVRGR --------------------------------MTK---G-ILGRKIGMTQVFG-ENGD---------LIPVTVVEASQNV ILQKK----SEE----I--DGY--NAIQVGY-------ED--KANK----------PAEGHAK----------------- ---AG-TAPKRFIREFRN--------VNVDEY-----EV---GQ-EVSV--N-T-FEAGDVIDVTGVSKGKGFQGAIKRH NQAR-GPMSHGS-HFHRA-PGSVGMA-SDAS-RVFKGQKMPGRMGGNTVTVQNLEVVQIDAENN---------------- ----------VILVKGN-VPGPKKGFVEIT-MANYDVLK-VDGTKS-GSVELSDAVF----AI-EP-NNNVLFEAINLQR ASLRQGTHAVKNRSA--------VR-GGGRKPW---------RQKGTGRAR--------QGT---IR-AP----QW---- RGGGIVFGPT-P-RSYSYKMPKKMRRLALRSALSFKVQEK----------------G-LTVVDAL----NLD-A------ --PKTKLVV--TESED--V---NVALSARNIPGVQ-V---------------TTAQGLNVLDITSADS----VVITESAA KKVENRLKEKFNSEV----TQNLVKQFDYSSVMEVPKIEKIVVNMGVG-DAVQNTKVLDDAVEELQAITGQKPLITKAKK SVATFRLREGMPIGAKVTLRGERMYDFLDKLIAVSLPRVRDFQGVSK-TAFDGRGNYTLGVKEQLIFPEID-----YDRV NKVRGMDIVIVTT-----------------------ANTDEEARELLSQFGMPFMSRVG-K--KIIDIPSDVTVS-V--- -E-G--N-TITVKGPKGELSRTM--NE-R--MTYKQDE-ST--LEV---VR-P--TDSKDDR-TVHGTTRALINNMIQGV KEGYQKTLELVGVGY--RAQMQG-ND--LILN--VGYSHPVEIKA-D-D-GITFGVE--K-NTTVTVAG-ISKEQVGAIA SNIRSVR------PPEPY---KGKGIRYQGEYVRRKEGK----------MIQQETRLKVADNSGAREVLTIKVLG-SGRK T--ANIGDVIVVSVKNATPG-G-------VVKKGEVVKAVVVRTKSGVRRNDGSYIKFDENACVIIR-DDKG-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGAATGN-GKTSGRGQKGQKARSGGS-V--- -RPGF-E-GGQLPLFRRLPK-RG--FTNVNLDQLVTPALLVES-GVVKIK---------ILG--TGS-L-D-K-K-LTV- KASKFSASAAEAIDAKGGAH-R---QHR--PKT---TGRS-KGGNYVTFG----------EYGLQAT--TTSWITSRQIE SARIAMTRFM------KRGGKVWIKIFPHTPYTQKPLEVRMGAGK---------GAVEGWIAVAKP-GRILFEI--AG-- VNEEVAREALRLASHKLPVKTKF-VKNKVRLKRHARVRNKL---AGTAEKPRLNIYRSNKHIYAQVIDD---V--SGKTL AQASTQ-EKDL---AN----ESG-SKVELSAKVGETVAKR--ASEKG-VKTIVFDRGGYLYH--GRVKALADAARENGLE F--------------------------------------------------------------ME-AKAVAKTIRIAPRK VRLVLDLIRGKSAGEAIAILKLK---------------------------------NKASSPVVEKLLMSALAN----A- EHNY-DMNTDELIVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSD-MHIKKGDNVKVIAGK------DK-GKE GKVVSTEPKKD--RVV--VEGVNIIKKHQK----PT--QF-NPE-GGILETEAAIHVSNVQ-LLDPKT-------NE--P --TRVGHKF----V--------DGKVR---IAKKSG---EEI--MGQKINPIGLRVG--VI-RDWEAKWYA------E-K D--FASLLHEDLKIRKYI--DNALQ-----EASVSHVEIERAA-N-RINIAIHTGKPGMVIGKGGSEIEKLRNKLNSLVH INVIEIKK---VDLDAKLVAENIARQLENRASFRRVQKQAITRAMKI-GAKGIKTQVSGRLGGADIARAEQYSEGTVPL- -HTLRADIGYAHAEADTTYGKLGVKVWIYMTINDPIADMLTRVRNANMVRHDKLEL-PASNIKKEIAEILKSEGFIKNVE YVE----D---D----KQGVIRLFLKYG---QNN-------E---RVITGLKRISKPGLRVYAKANEVPKVLNGLGIALV STSEGVVTDKEARKRNIGGEILGYIWMAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTERSVYTVIRA VHKYKDSR-EQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKLRKVYVGRVVSDKMDKTITVLVETYKTHKLYG KRVKYSKKYKTHDEN--NSAKLGDTVKIQETRPLSATKRFRLVEIVEES------------------------------- -MARSI-KKGPFADD-HLKKKVEAQSG---SEKKQ----VIKTWSRRSTIFPDFIGHTFAVYDGRKHVPVFVTE-DMVGH KLGEFAPTRTFKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_agalactiae_2603V/R Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTN------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYILAPKGLEVGQRIISGP-E-AD-IKVGNALPLA NIPVGTVIHNIELQPGKGAELIRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRN -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-ELSV--E-Q-FEAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKRLAGRMGGNRVTVQNLEIVQVIPEKN---------------- ----------VVLIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-SSVELNEAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVENL----SFA-A------ --PKTALVI--LEEGN--E---FAALSARNLPNVT-V---------------ATATTASVLDIVNADK----LLVTKEAI STIENRLKEKYTNEV----VPALTEKFNYSSVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKGLGMPFMSRIG-N--KVITLPAGVEII-N--- -K-D--N-VVTVKGPKGQLTREF--NK-N--IGITVEG-TE--VTV---TR-P--NDSKEMK-TIHGTTRANLNNMVVGV SEGFKKALEMRGVGY--RAQLQG-SK--LVLS--VGKSHQDEVEA-P-E-GVTFEVP--T-PTTINVIG-INKESVGQTA AYVRSLR------SPEPY---KGKGIRYVGEFVRRKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRMPK-RG--FSNVNLDQLVTPVVLKEA-GIVRVK---------ILG--NGE-L-T-K-K-LSV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEVAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SNG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADSARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKNVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVV--VEGVALIKKHQK----PN--NE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--NKELA-----DASVSTIEIERAV-N-KVIVSLHTAKPGMVIGKGGANVDALRGQLNKLVH INIIEIKQ---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIADILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---QNG-------E---RVITNLKRISKPGLRVYTKHEDMPKVLNGLGIAIV STSEGLLTDKEARQKNIGGEVLAYIWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKLRKTLYGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEKA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_agalactiae_A909 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTN------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYILAPKGLEVGQRIISGP-E-AD-IKVGNALPLA NIPVGTVIHNIELQPGKGAELIRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRN -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-ELSV--E-Q-FEAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKRLAGRMGGNRVTVQNLEIVQVIPEKN---------------- ----------VVLIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-SSVELNEAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVENL----SFA-A------ --PKTALVI--LEEGN--E---FAALSARNLPNVT-V---------------ATATTASVLDIVNADK----LLVTKEAI STIENRLKEKYTNEV----VPALTEKFNYSSVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKGLGMPFMSRIG-N--KVITLPAGVEII-N--- -K-D--N-VVTVKGPKGELTREF--NK-N--IGITVEG-TE--VTV---TR-P--NDSKEMK-TIHGTTRANLNNMVVGV SEGFKKALEMRGVGY--RAQLQG-SK--LVLS--VGKSHQDEVEA-P-E-GVTFEVP--T-PTTINVIG-INKESVGQTA AYVRSLR------SPEPY---KGKGIRYVGEFVRRKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRMPK-RG--FSNVNLDQLVTPVVLKEA-GIVRVK---------ILG--NGE-L-T-K-K-LSV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEVAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SNG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADSARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKNVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVV--VEGVALIKKHQK----PN--NE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--NKELA-----DASVSTIEIERAV-N-KVIVSLHTAKPGMVIGKGGANVDALRGQLNKLVH INIIEIKQ---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIADILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---QNG-------E---RVITNLKRISKPGLRVYTKHEDMPKVLNGLGIAIV STSEGLLTDKEARQKNVGGEVLAYIWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKLRKTLYGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEKA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_equi_equi_4047 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-D-AD-IKVGNALPLV NIPVGTVVHNIELKPGKGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSN-K-LLVRRR --------------------------------MTK---G-ILGEKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAIQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-EITV--D-I-FAAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VSPN-RVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-STVELNDDIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVESL----SFA-A------ --PKTALVL--VEEGN--E---FAALSARNLPNVA-V---------------ATAATASVLDIVNADK----LLVTKEAI STIENRLKEKYTNEV----IPALTEKFNYTSVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKGLGMPFMSRIG-N--KVIIIPAGVEII-N--- -N-D--N-VVTVKGPKGELTREF--NK-N--IEIKVEG-NE--MTL---VR-P--DDSKEMK-TIHGTTRANLNNMVVGV SEGFKKELEMKGVGY--RAQLQG-SK--LVLS--VGKSHQDEVEA-P-E-GITFTVA--N-PTSISVEG-INKEVVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRLKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLMK-L--HELKPAKGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRIPK-RG--FTNVNLDQLVTPVVLKEA-GIVRVK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEV--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKKVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GVE AVVLKALPKVN--KVI--VEGVAIIKKHQK----PN--SE-NPQ-GAIVEKEAPIHASNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--NKELA-----EASVSTIEIERAV-N-KVIVSLHTAKPGMVIGKGGANVDALRAQLNKLVH INIIEIKQ---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARSEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQVKHEVLEV-PASNIKKGIAEILKREGFIKNVE VIE----D---G----KQGIIRVFLKYG---QNG-------E---RVITNLKRVSKPGLRIYSKREDVPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKLRKTLVGRVVSDKMDKTITVIVETKRNHPVYG KRINYSKKYKAHDEK--NLAKEGDIVRIMETRPLSATKRFRLVEIVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_equi_zooepidemicus_H70 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-D-AD-IKIGNALPLA NIPVGTVVHNIELKPGKGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSN-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAIQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-EITV--D-I-FAAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-STVELNDAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVESL----SFA-A------ --PKTALVL--VEEGN--E---FAALSARNLPNVA-V---------------ATAATASVLDIVNADK----LLVTKEAI STIENRLKEKYTNEV----IPALTEKFNYTSVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKGLGMPFMSRIG-N--KVIIIPAGVEII-N--- -N-D--N-VVTVKGPKGELTREF--NK-N--IEIKVEG-NE--MTL---VR-P--DDSKEMK-TIHGTTRANLNNMVVGV SEGFKKELEMKGVGY--RAQLQG-SK--LVLS--VGKSHQDEVEA-P-E-GITFTVA--N-PTSISVEG-INKEVVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRLKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLMK-L--HELKPAKGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRIPK-RG--FTNVNLDQLVTPVVLKEA-GIVRVK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEV--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKKVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GVE AVVLKALPKVN--KVI--VEGVAIIKKHQK----PN--SE-NPQ-GAIVEKEAPIHASNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--NKELA-----EASVSTIEIERAV-N-KVIVSLHTAKPGMVIGKGGANVDALRAQLNKLVH INIIEIKQ---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARSEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQVKHEVLEV-PASNIKKGIAEILKREGFIKNVE VIE----D---G----KQGIIRVFLKYG---QNG-------E---RVITNLKRVSKPGLRIYSKREDVPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKLRKTLVGRVVSDKMDKTITVIVETKRNHPVYG KRINYSKKYKAHDEK--NLAKEGDIVRIMETRPLSATKRFRLVEIVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_gordonii_Challis_CH1 Concatenation of 2 sequences MGIRVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKSKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DAVEAVVKTIEYDPNRSANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-E-AD-IKVGNALPLA NIPVGTLVHNIELKPGRGGELVRAAGASAQVLGQ--EGKYTLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-EAGE---------LIPVTVIEATPNV VLQVK----TVE----T--DGY--NAVQVGF-------DD--LSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-EITV--D-T-FAAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKHLAGRMGGNRVTIQNLEIAQVVPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEA-GEVVLNDAIF----GI-EP-NESVVFDVIISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPRKVRRLALKSVYSEKVAEN----------------K-FVAVDSL----SFT-A------ --PKTALVI--LEEGN--E---FAALSARNLPNVK-V---------------ATATTASVLDIVNSDK----LLVTQAAI SKIENRLKEKYLKEV----VPALTEKFNYSSVMAVPKVDKIVLNMGVG-DAVSNAKNLEKAAEELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKTRGLDIVIVTT-----------------------ANTDEESRELLTGLGMPFMSRIG-N--KVIVLPAGVEIT-N--- -N-D--N-VVTVKGPKGELTREF--SK-D--IEIRVEG-TE--VTL---HR-P--NDSKEMK-TIHGTTRALLNNMVIGV SEGFKKELEMRGVGY--RAQLQG-KK--LVLA--VGKSHPDEVEA-P-E-GITFELP--N-PTTIVISG-ISKEAVGQTA AYVRSLR------APEPY---KGKGIRYVGEFVRRKEGK----------MIQTETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRKDGSYIKFDENAAVIIR-EDKT-PRGTRIF GPVARELR-DGGFMKIVSLAPEVLMK-L--HELQPAAGS-RKVRNRVG-RGTSSGN-GKTAGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FLNVNLDQLVTPVVLVES-GIVKVK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEEAITAKGGSV-R---EFR--GKM---RGEA-KGGKEVAFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEV--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKVRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK SRLILDNIRGKNVADAIAILKFT---------------------------------PNKAAGIIEKVLNSAIAN----A- ENNF-GLEKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTSHITVVVAE-MFVKKGDKVRVIAGK------DK-GVE ALVVTALPKVN--KVV--VEGVNIVKKHQK----PN--NE-HPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFV--QKELA-----DAAVSTIEIERAV-N-KVNVSLHTAKPGMVIGKGGANVDALRAKLNKLVH INIIEIKS---PDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARSEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQANHEVLEV-PASNIKKGIAEILKREGFVKNVE FIE----D---D----KQGIIRVFLKYG---QNG-------E---KVITGLKRVSKPGLRVYKKREDLPKVLNGLGIAIL STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAAKIVETATRTGAEVAGPIPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKLRKVLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------RK >FIRM_Streptococcus_mutans_UA159 Concatenation of 2 sequences -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AD-TAPKRFIREFKN----------IEGL-----EV---GQ-EITV--E-Q-FEAGDVVDVTGTTKGKGFQGAIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKGKNLAGRMGGNRVTVQNLEVVQVVPEKN---------------- ----------VILIKGN-VPGAKKSLIIIK-------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----NRLKEKYLNEV----VPALTEKFNYTSVMAVPKVDKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGQRMYEFLDKLVTVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDNV DKVRGLDIVIVTT-----------------------ANTDEESRELLTGLGMPFMSRIG-N--KVITLPAGVEVT-N--- -K-D--N-VVTVKGPKGELTREF--PK-V--IEIKIEG-TE--VTL---HR-P--NDSKEMK-TIHGTARANLNNMVIGV SEGFKKELEMRGVGY--RAQLQG-KK--LVLS--VGKSHPDEVEA-P-E-GITFEVP--T-ATAIVVNG-INKEVVGQTA AYIRGLR------VPEPY---KGKGIRYAGEYVRRKEGK----------MIQSESRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIR-DDKT-PRGTRIF GPVARELR-EGNFMKIVSLAPEVLMK-L--HELKPAQGS-RKTRNRVG-RGSSSGN-GKTAGRGQKGQKARSGGN-I--- -RSGF-E-GGQTPLFRRLPK-RG--FTNVNLDQLVTPVVLVET-GIVKIK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAIIAKGGSI-R---EFR--GKM---RGEA-KGGKEVAFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKIMFEI--AD-- VPEEVAREALRLASHKLPVKTKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKNVADAIAILKFT---------------------------------PNKAARIVEKTLNSAVAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVEE-MFVKKGDKVRVIAGK------DK-GVE AVVLKAFPKIN--KVV--VEGVAIVKKHQK----PN--NE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YNKKSG---EVL--M---------RVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--QKELA-----DAAVSTIEIERAV-N-KVNVSLHTAKPGMVIGKGGANVDALRAQLNKLVH INIVEIKS---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARSEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQANHSVVEA-PASNIKRGIAEILKCEGFVKDVE VIE----D---D----KQGIIRIFLKYG---QNG-------E---RVITGLKRISKPGLRVYTKREDVPKVLNGLGIAII STSEGLLTDREARQKNIGGEVITYVW------------------------------------------------------ -------------------------------------------------RRTLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NIAKAGDIVRIMETRPLSATKRFRLVEVVEEA------------------------------- --------------------------------------------------------------MNRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------T--DDK----KTR------R- >FIRM_Streptococcus_pneumoniae_ATCC_700669 Concatenation of 2 sequences MGIRVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVALKSKAGRNNNGRITVRH-QGGGHKRF---- YRLVDFK-R--NK-DNVEAVVKTIEYDPNRSANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-E-AD-IKVGNALPLA NIPVGTLIHNIELKPGRGGELVRAAGASAQVLGS--EGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-EAGE---------LIPVTVIEATPNV VLQVK----TVE----T--DGY--NAIQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------VEGL-----EV---GA-EITV--E-T-FAAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKGKNLAGRMGGDRVTIQNLEVVQVVPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVTLFD-QTGKEA-GQVVLNDAVF----GI-EP-NESVVFDVIISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSEKVAEN----------------K-FVAVDAL----SFT-A------ --PKTALVI--LEEGN--E---FAALSARNLPNVK-V---------------ATATTASVLDIANSDK----LLVTQAAI SKIENRLKEKYLNEV----VPALTEQFNYSSVMAVPKVDKIVLNMGVG-EAVSNAKSLEKAAEELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKTRGLDIVIVTT-----------------------ANTDEESRALLTGLGMPFMSRIG-N--KVIVLPAGVELA-N--- -N-D--N-VVTVKGPKGELTREF--SK-D--IEIRVEG-TE--ITL---HR-P--NDSKEMK-TIHGTTRALLNNMVVGV SEGFKKELEMRGVGY--RAQLQG-SK--LVLA--VGKSHPDEVEA-P-E-GITFELP--N-PTTIVVSG-ISKEVVGQTA AYVRSLR------SPEPY---KGKGIRYVGEFVRRKEGK----------MIQTETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIR-EDKT-PRGTRIF GPVARELR-EGGFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLDQLVTPVVLIEA-GIVKIK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEEAITAKGGSV-R---EFR--GKM---RGEA-KGGKEVAFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKLRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVAVGKLVAER--ANAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK SRLVLDNIRGKSVADAIAILTFT---------------------------------PNKAAEIILKVLNSAVAN----A- ENNF-GLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAE-MFVKKGDKVRVIAGK------DK-GTE AVVLTALPKVN--KVI--VEGVNIVKKHQR----PT--NE-LPQ-GGIIEKEAAIHVSNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFV--QKELA-----DAAVSTIEIERAV-N-KVNVSLHTAKPGMVIGKGGANVDALRAKLNKLVH INIIEIKQ---PDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIAEILKREGFVKNVE IIE----D---D----KQGVIRVFLKYG---PNG-------E---KVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAIL STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKLRKVLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------RK >FIRM_Streptococcus_pneumoniae_R6 Concatenation of 2 sequences MGIRVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVALKSKAGRNNNGRITVRH-QGGGHKRF---- YRLVDFK-R--NK-DNVEAVVKTIEYDPNRSANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-E-AD-IKVGNALPLA NIPVGTLIHNIELKPGRGGELVRAAGASAQVLGS--EGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-EAGE---------LIPVTVIEATPNV VLQVK----TVE----T--DGY--NAIQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------VEGL-----EV---GA-EITV--E-T-FAAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKGKNLAGRMGGDRVTIQNLEVVQVVPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVTLFD-QTGKEA-GQVVLSDAVF----GI-EP-NESVVFDVIISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSEKVAEN----------------K-FVAVDAL----SFT-A------ --PKTALVI--LEEGN--E---FAALSARNLPNVK-V---------------ATATTASVLDIANSDK----LLVTQAAI SKIENRLKEKYLNEV----VPALTEQFNYSSVMAVPKVDKIVLNMGVG-EAVSNAKSLEKAAEELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKTRGLDIVIVTT-----------------------ANTDEESRALLTGLGMPFMSRIG-N--KVIVLPAGVELA-N--- -N-D--N-VVTVKGPKGELTREF--SK-D--IEIRVEG-TE--VTL---HR-P--NDSKEMK-TIHGTTRALLNNMVVGV SEGFKKELEMRGVGY--RAQLQG-SK--LVLA--VGKSHPDEVEA-P-E-GITFELP--N-PTTIVVSG-ISKEVVGQTA AYVRSLR------SPEPY---KGKGIRYVGEFVRRKEGK----------MIQTETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIR-EDKT-PRGTRIF GPVARELR-EGGFMKIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FTNVNLDQLVTPVVLIEA-GIVKIK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEEAITAKGGSV-R---EFR--GKM---RGEA-KGGKEVAFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKLRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVAVGKLVAER--ANAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK SRLVLDNIRGKSVADAIAILTFT---------------------------------PNKAAEIILKVLNSAVAN----A- ENNF-GLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAE-MFVKKGDKVRVIAGK------DK-GTE AVVLTALPKVN--KVI--VEGVNIVKKHQR----PT--NE-LPQ-GGIIEKEAAIHVSNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFV--QKELA-----DAAVSTIEIERAV-N-KVNVSLHTAKPGMVIGKGGANVDALRAKLNKLVH INIIEIKQ---PDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIAEILKREGFVKNVE IIE----D---D----KQGVIRVFLKYG---PNG-------E---KVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAIL STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKLRKVLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------RK >FIRM_Streptococcus_pyogenes_MGAS10394 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKSKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-D-AD-IKVGNALPLA NIPVGTVVHNIELKPGKGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-ELSV--E-Q-FEAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKRLAGRMGGNRVTVQNLEIVQVILEKN---------------- ----------VILVKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-SSVELNDAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVEGL----SFA-A------ --PKTALVL--VEEGN--E---FAALSARNLPNVT-V---------------ATAATASVLDIVNADK----LLVTKEAI STIENRLKEKYTNEV----IPALTEKFNYTSVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIS-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKGLGMPFMSRIG-N--KVITMPAGVELT-N--- -N-N--N-VITVKGPKGELTREF--NK-N--IEIKVEG-TE--ITV---VR-P--NDSKEMK-TIHGTTRANLNNMVVGV SEGFKKDLEMKGVGY--RAQLQG-TK--LVLS--VGKSHQDEVEA-P-E-GITFTVA--N-PTSISVEG-INKEVVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRLKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLMK-L--HELKAAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRIPK-RG--FTNVNLDQLVTPAILKDA-GIVRVK---------VLG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAIIAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKDV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ISS-AKAMARTVRVSPRK TRLVLDLIRGKKVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVI--VEGVGMIKKHQK----PN--TE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YSKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--NKELA-----DASVSTIEIERAV-N-KVIVSLHTAKPGMVIGKGGANVDALRGQLNKLVH INIIEIKQ---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQVKHEVLEV-PASNIKKGIAEILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---KNG-------E---RVITNLKRISKPGLRVYAKRDDMPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKLRKTLYGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA--------------MLLNSSRCGTLFKGENY KMGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_pyogenes_NZ131 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKSKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-D-AD-IKVGNALPLA NIPVGTVVHNIELKPGKGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-ELSV--E-Q-FEAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKRLAGRMGGNRVTVQNLEIVQVIPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-SSVELNDAVF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVEGL----SFA-A------ --PKTALVL--VEEGN--E---FAALSARNLPNVT-V---------------ATAATASVLDIVNADK----LLVTKEAI STIENRLKEKYTNEV----IPALTEKFNYTSVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIS-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKALGMPFMSRIG-N--KVITMPAGVELT-N--- -N-N--N-VITVKGPKGELTREF--NK-N--IEIKVEG-TE--ITV---VR-P--NDSKEMK-TIHGTTRANLNNMVVGV SEGFKKDLEMKGVGY--RAQLQG-TK--LVLS--VGKSHQDEVEA-P-E-GITFTVA--N-PTSISVEG-INKEVVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRLKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMKIVSLAPEVLMK-L--HELKAAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRIPK-RG--FTNVNLDQLVTPAILKDA-GIVRVK---------VLG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAIIAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKDV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKKVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVI--VEGVGMIKKHQK----PN--TE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YSKKSG---EVL--M---------RVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--NKELA-----DASVSTIEIERAV-N-KVIVSLHTAKPGMVIGKGGANVDALRGQLNKLVH INIIEIKQ---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQVKHEVLEV-PASNIKKGIAEILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---KNG-------E---RVITNLKRISKPGLRVYAKRDDMPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVVAYVWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKLRKTLYGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEKA------------------------------- -MGRSL-KKAPFVDE-HLMKKVEAQAH---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_sanguinis_SK36 Concatenation of 2 sequences MGIRVYKPTTNGRRNMTSLDFAE-FTTS------------TP-EKSLLVSLKSKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DAVEAVVKTIEYDPNRSANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-E-AD-IKVGNALPLA NIPVGTLVHNIELKPGRGGELVRAAGASAQVLGQ--EGKYTLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-EAGE---------LIPVTVVEAAPNV VLQVK----TVE----T--DGY--NAVQVGF-------DD--LSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GA-EITV--D-T-FEAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKRLAGRMGGNRVTIQNLEIVQVVPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEA-GEVVLNDAVF----GI-EP-NESVVFDVIISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGIVFGPT-P-RSYAYKLPRKVRRLALKSVYSEKVAEN----------------K-FVAVDSL----SFT-A------ --PKTALVI--LEEGN--E---FAALSARNLPNVK-V---------------ATATTASVLDIVNSDK----LLVTQAAI SKIENRLKEKYLKEV----VPSLTEKFNYSSVMAVPKVDKIVLNMGVG-DAVSNAKNLEKAAEELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKTRGLDIVIVTT-----------------------ANTDEESRELLTGLGMPFMSRIG-N--KVIVLPAGVEIS-N--- -K-D--N-VVTVKGPKGELTREF--SK-D--IEIRVEG-TE--VTL---HR-P--NDSKEMK-TIHGTTRALLNNMVVGV SEGFKKELEMRGVGY--RAQLQG-KK--LVLS--VGKSHPDEVEA-P-E-GITFELP--N-PTTIVVSG-ISKEVVGQTA AYVRSLR------APEPY---KGKGIRYVGEFVRRKEGK----------MIQTETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKSGARRKDGSYIKFDENAAVIIR-EDKT-PRGTRIF GPVARELR-DGGFMKIVSLAPEVLMK-L--HELQPAAGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RLGF-E-GGQTPLFRRLPK-RG--FLNVNLDQLVTPVVLIEA-GIVKIK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEEAITAKGGSV-R---EFR--GKM---RGEA-KGGKEVAFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEV--AG-- VSEEIAREALRLASHKLPVKCKF-VKNKIRQKRHRRVRGKL---SGTADRPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK SRLVLDNIRGKNVADAIAILKFT---------------------------------PNKAAGIIEKVLNSAIAN----A- ENNF-GLEKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTSHITVVVAE-MFVKKGDKVRVIAGK------DK-GVE ALVVTALPKVN--KVV--VEGVNIVKKHQK----PN--NE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFV--QKELA-----DAAISTIEIERAV-N-KVNVSLHTAKPGMVIGKGGANVDALRAKLNKLVH INIIEIKR---PDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARSEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQANHEVLEV-PASNIKKGIAEILKREGFVKNVE IIE----D---D----KQGIIRVFLKYG---QNG-------E---KVITGLKRISKPGLRVYKKREDLPKVLNGLGIAIL STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAAKIVETATRTGAEVAGPIPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKLRKVLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------RK >FIRM_Streptococcus_suis_05ZYH33 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVALKSKAGRNNNGRITVRH-QGGGHKRF---- YRLVDFK-R--NK-DGVEAIVKTIEYDPNRSANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-E-AD-IKVGNALPLA NIPVGTVVHNIELKPGRGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATVGTVGNEQHGLVNLGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--AAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GQ-EITV--E-T-FAAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKGKNLAGRMGGNRVTIQNLEVVQVVPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVTLFD-QTGKQA-GEVVLNDAIF----GI-EP-NQAVVFDVIISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPQKVRRLALKSVYSEKVAEN----------------K-FVAVNSL----EFT-A------ --PKTALVI--LEEGN--E---FAALSARNIPGVK-V---------------ATATTASVLDIANADK----LLVTQAAI SKIENRLKEKYLNEV----VPALTEQFNYSSVMAVPKVDKIVLNMGVG-DAVSNAKNLEKAAQELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVTVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKTRGMDIVIVTT-----------------------ANTDEESRALLTGLGMPFMSRIG-N--KVITLPAGVELA-Q--- -NNG----VVTVKGPKGELTREF--PT-A--IEIRVEG-AE--VTL---HR-P--NDSKEMK-TIHGTSRANLNNMVVGV SEGFKKELEMRGVGY--RAQLAG-NK--LTLA--VGKSHPDEVVA-P-E-GITFEVP--T-PTQIVVSG-INKEVVGQTA AYIRSLR------APEPY---KGKGIRYVGEFVRRKEGK----------MIQTETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDIIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRADGSYIKFDENAAVIIR-EDKN-PRGTRIF GPVARELR-DGGFMKIVSLAPEVLMK-L--HELQPATGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RPGF-E-GGQTPLFRRLPK-RG--FTNVNLDQLVTPVVLIEA-GIVKIK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEEAITSKGGSV-R---EFR--GKM---RGEA-KGGKQVDFG----------QYGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEV--AG-- VSEEIAREAFRLAGHKLPVKVKF-VKNKIRQKRHRRVRGKI---SGTAARPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALAESARENGLK F-------------------------------------------------------------ITS-AKATARTVRVSPRK SRLVLDNIRGKSVADAIAILKFT---------------------------------PNKAAGIIEGVLNSAIAN----A- ENNF-GLEKANLVVSEAFANEGPTLKRFRPRAKGSASPINKRTAHITVVVAE-MFVKKGDKVRVIAGK------DK-GVE AVVVTALPKVN--KVI--VEGVNIVKKHQK----SN--SE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRNFI--KKELA-----DASTSTIEIERAV-N-KVIVSIHTAKPGMVIGKAGSNVDALRAQLNKLVH INIIEIKQ---PDLDAHLVGESIARQLEQRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEALTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIATILKNEGFVKNVE FIE----D---D----KQGIIRVFLKYG---PNG-------E---KVITNLKRVSKPGLRVYSKREDIPKVLNGLGIAII STSEGLLTDKQARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAAKIVETATRTGAQVAGPVPLPTERSFYTIIRA THKYKDSR-EQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKLRKVLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA--MRGQDNEHGNWGSVHLPSRCGTYFKGENT KMGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------RK >FIRM_Streptococcus_suis_98HAH33 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVALKSKAGRNNNGRITVRH-QGGGHKRF---- YRLVDFK-R--NK-DGVEAIVKTIEYDPNRSANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-E-AD-IKVGNALPLA NIPVGTVVHNIELKPGRGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATVGTVGNEQHGLVNLGKAGRS -RWK-----GIR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--AAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GQ-EITV--E-T-FAAGDVVDVTGT------------- -------MAHGS-RYHRR-PGSMGP--VAPN-RVFKGKNLAGRMGGNRVTIQNLEVVQVVPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVTLFD-QTGKQA-GEVVLNDAIF----GI-EP-NQAVVFDVIISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYAYKLPQKVRRLALKSVYSEKVAEN----------------K-FVAVNSL----EFT-A------ --PKTALVI--LEEGN--E---FAALSARNIPGVK-V---------------ATATTASVLDIANADK----LLVTQAAI SKIENRLKEKYLNEV----VPALTEQFNYSSVMAVPKVDKIVLNMGVG-DAVSNAKNLEKAAQELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVTVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKTRGMDIVIVTT-----------------------ANTDEESRALLTGLGMPFMSRIG-N--KVITLPAGVELA-Q--- -NNG----VVTVKGPKGELTREF--PT-A--IEIRVEG-AE--VTL---HR-P--NDSKEMK-TIHGTSRANLNNMVVGV SEGFKKELEMRGVGY--RAQLAG-NK--LTLA--VGKSHPDEVVA-P-E-GITFEVP--T-PTQIVVSG-INKEVVGQTA AYIRSLR------APEPY---KGKGIRYVGEFVRRKEGK----------MIQTETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDIIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRADGSYIKFDENAAVIIR-EDKN-PRGTRIF GPVARELR-DGGFMKIVSLAPEVLMK-L--HELQPATGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGGG-V--- -RPGF-E-GGQTPLFRRLPK-RG--FTNVNLDQLVTPVVLIEA-GIVKIK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEEAITSKGGSV-R---EFR--GKM---RGEA-KGGKQVDFG----------QYGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEV--AG-- VSEEIAREAFRLAGHKLPVKVKF-VKNKIRQKRHRRVRGKI---SGTAARPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALAESARENGLK F-------------------------------------------------------------ITS-AKATARTVRVSPRK SRLVLDNIRGKSVADAIAILKFT---------------------------------PNKAAGIIEGVLNSAIAN----A- ENNF-GLEKANLVVSEAFANEGPTLKRFRPRAKGSASPINKRTAHITVVVAE-MFVKKGDKVRVIAGK------DK-GVE AVVVTALPKVN--KVI--VEGVNIVKKHQK----SN--SE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKF----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRNFI--KKELA-----DASTSTIEIERAV-N-KVIVSIHTAKPGMVIGKAGSNVDALRAQLNKLVH INIIEIKQ---PDLDAHLVGESIARQLEQRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEALTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIATILKNEGFVKNVE FIE----D---D----KQGIIRVFLKYG---PNG-------E---KVITNLKRVSKPGLRVYSKREDIPKVLNGLGIAII STSEGLLTDKQARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAAKIVETATRTGAQVAGPVPLPTERSFYTIIRA THKYKDSR-EQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKLRKVLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA--MRGQDNEHGNWGSVHLPSRCGTYFKGENT KMGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------RK >FIRM_Streptococcus_thermophilus_CNRZ1066 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-D-AD-IKVGNALPLA NIPVGTVIHNIELKPGKGAELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLINLGKAGRN -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-EAGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GS-EITV--D-I-FEAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-STVELNDAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVEAL----SFA-A------ --PKTALVI--VEEGN--K---FAELSARNLANVT-V---------------ATPATASVLDIVNADK----LLVTKEAI SSIENRLKEKYTNEV----IPALTEQFNYSSVMAVPKVDKIVINMGVG-EAVNNAKTLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDNV DKVRGMDIVIVTT-----------------------ANTDEEGRELLKGLGMPFMSRIG-N--KVITLPAGVEIT-N--- -N-D--N-VVTVKGPKGELTREF--NK-N--IEIKVEG-NE--VTL---HR-P--NDSKENK-TIHGTSRANLNNMVVGV SEGFKKELEMHGVGY--RAQLQG-TK--LVLS--VGKSHQDEVEA-P-E-GITFEVP--S-ATSIVVSG-INKEVVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRRKEGK----------MIQQESRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVATVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRSDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMRIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGVG-L--- -RPGF-E-GGQTPLFRRLPK-RG--FTNVNLEQLVTPVVLKEA-GIIRVK---------VLG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEVAREAFRLASHKLPVKSKF-VKNKLRQKRHRRIRGKL---SGTADRPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAIVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADSARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKNVADAIAILKFT---------------------------------PNKAARIVEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVV--VEGVAIIKKHQK----PS--TE-NPQ-GAIVEKEAPIHASNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGLRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--QKELA-----DASVSTIEIVRAV-N-KVIVSLHTAKPGMVIGKGGSNVDALRAQLNKLVH INIVEIKK---PDLDAHLVGETIARQLEQRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIAEILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---QNG-------E---RVITNLKRISKPGLRVYSKREDIPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAGKIVENATRTGATVAGPVPLSTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKLRKTLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKHFRLVEVVEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_thermophilus_LMD-9 Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRLIDFK-R--NK-DGVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIVSGP-D-AD-IKVGNALPLA NIPVGTVIHNIELKPGKGAELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLINLGKAGRN -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIVRRR --------------------------------MTK---G-ILGKKVGMTQIFT-EAGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GS-EITV--D-I-FEAGDIVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-STVELNDAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVEAL----SFA-A------ --PKTALVI--VEEGN--K---FAELSARNLANVT-V---------------ATPATASVLDIVNADK----LLVTKEAI SSIENRLKEKYTNEV----IPALTEKFNYSSVMAVPKVDKIVINMGVG-EAVNNAKTLEKAAAELALISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKVRGMDIVIVTT-----------------------ANTDEEGRELLKGLGMPFMSRIG-N--KVITLPAGVEIT-N--- -N-D--N-VVTVKGPKGELTREF--NK-N--IEIKVEG-NE--VTL---HR-P--NDSKENK-TIHGTSRANLNNMVVGV SEGFKKELEMHGVGY--RAQLQG-TK--LVLS--VGKSHQDEVEA-P-E-GITFEVP--S-ATSIVVSG-INKEVVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRRKEGK----------MIQQESRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVATVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRSDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVARELR-EGGYMRIVSLAPEVLMK-L--HELKPAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKARSGVG-L--- -RPGF-E-GGQTPLFRRLPK-RG--FTNVNLDQLVTPVVLKEA-GIIRVK---------VLG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSHWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVAPVKR-GKVMFEI--AG-- VSEEVAREALRLASHKLPVKSKF-VKNKLRQKRHRRVRGKL---SGTADRPRLNIFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKEV---------SKG-TKTEQAIVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADSARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKNVADAIAILKFT---------------------------------PNKAARIVEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVV--VEGVAIIKKHQK----PS--AE-NPQ-GAIVEKEAPIHASNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YNKKSG---EVL--MGQKVHPIGLRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--QKELA-----DASVSTIEIVRAV-N-KVIVSLHTAKPGMVIGKGGSNVDALRAQLNKLVH INIVEIKK---PDLDAHLVGETIARQLEQRVAFRRAQKQAIQRAMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEAHTTYGKLGVKVWIYMVMTDPIADFLTRIRNANQAKHEVLEV-PASNIKKGIAEILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---QNG-------E---RVITNLKRISKPGLRVYSKREDIPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAGKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKLRKTLVGRVVSDKMDKTITVVVETKRNHPVYG KRINYSKKYKAHDEN--NVAKEGDIVRIMETRPLSATKRFRLVEVVEEA------------------------------- -MGRSL-KKGPFVDG-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Streptococcus_uberis_0140J Concatenation of 2 sequences MGIKVYKPTTNGRRNMTSLDFAE-ITTS------------TP-EKSLLVSLKNKAGRNNNGRITVRH-QGGGHKRH---- YRVIDFK-R--NK-DNVEAVVKTIEYDPNRTANIALVHYT-DGVKAYIIAPKGLEVGQRIISGP-E-AD-IKIGNALPLA NIPVGTVIHNIEMKPGKGGELVRAAGASAQVLGQ--EGKYVLVRLQSGEVRMILGTCRATIGSVGNEQQSLVNIGKAGRN -RWK-----GVR-P-TVRGSVMNPNDHPHGGGEGKA-P--VGRKAPSTP---WGKPALGLKTR-NKKAKSD-K-LIIRRR --------------------------------MTK---G-ILGKKVGMTQIFT-ESGE---------FIPVTVIEATPNV VLQVK----TVE----T--DGY--EAVQVGF-------DD--KSNK----------PAKGHVK----------------- ---AN-TAPKRFIREFKN----------IEGL-----EV---GS-EITV--E-S-FSAGDVVDVTGTSKGKGFQGVIKRH GQSR-GPMAHGS-RYHRR-PGSMGP--VAPN-RVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKN---------------- ----------VILIKGN-VPGAKKSLITIK-MANVKLFD-QTGKEV-SSVELNDAIF----GI-EP-NESVVFDVVISQR ASLRQGTHAVKNRSA--------VS-GGGRKPW---------RQKGTGRAR--------QGS---IR-SP----QW---- RGGGVVFGPT-P-RSYGYKLPQKVRRLALKSVYSAKVAED----------------K-FVAVEGL----SFA-A------ --PKTALVI--VEEGN--E---FAALSARNLPNVK-V---------------ATATTASVLDIVNSDK----LLVTKEAI STIENRLKEKYTNEV----IPALSEKFNYTTVMAVPKVEKIVLNMGVG-DAVSNAKNLEKAAAELELISGQKPLITKAKK SIAGFRLREGVAIGAKVTLRGERMYEFLDKLVTVSLPRVRDFHGVPT-KSFDGRGNYTLGVKEQLIFPEIN-----FDDV DKVRGLDIVIVTT-----------------------ANTDEESRELLKGLGMPFMSRIG-N--KIITMPAGVELK-N--- -D-N--N-VVTVKGPKGELTREF--NK-N--IEIKVEG-TE--ITV---SR-P--NDSKEMK-TIHGTTRALLNNMVQGV SEGFKKELEMKGVGY--RAQLQG-NK--LVLS--VGKSHQDEVEA-P-E-GITFTVA--T-PTTIAVEG-ISKELVGQTA AYIRSLR------SPEPY---KGKGIRYVGEYVRLKEGK----------MIQQETRLKVADNSGAREILTIKVLG-SGRK F--ANIGDVIVASVKQATPG-G-------AVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIR-DDKT-PRGTRIF GPVAREMR-EAGYMKIVSLAPEVLMK-L--HELKAAEGS-RKVRNRVG-RGTSSGN-GKTSGRGQKGQKSRSGGG-V--- -RLGF-E-GGQTPLFRRMPK-RG--FSNVNLDQLVTPVVLKEA-GIVRVK---------ILG--NGE-L-T-K-K-LTV- KAAKFSKSAEAAITAKGGSI-R---EFR--GKM---RGEA-KGGKEVSFG----------EYGLQAT--TSSWITNRQIE AARIAMTRYM------KRGGKVWIKIFPHKSYTAKAIGVRMGSGK---------GAPEGWVSPVKR-GKVMFEI--AG-- VSEEVAREAFRLAGHKLPVKVKF-VKNKTRQKRHRRVRGKL---SGTAERPRLNVFRSNTGIYAQVIDD---V--AGVTL ASASTL-DKDV---------SKG-TKTEQAVVVGKLVAER--AVAKG-ISEVVFDRGGYLYH--GRVKALADAARENGLK F-------------------------------------------------------------ITS-AKAMARTVRVSPRK TRLVLDLIRGKKVADAIAILKFT---------------------------------PNKAARVIEKTLNSAIAN----A- ENNF-GLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVAE-MFVKKGDKVRVIAGK------DK-GTE AVVLKALPKVN--KVV--VEGVGMIKKHQK----PN--AE-NPQ-GAIVEKEAPIHVSNVQ-VLD-KN-------GV--A --GRVGYKV----V--------DGKVR---YSKKSG---EVL--MGQKVHPIGMRVG--II-RDWDAKWYA------E-K E--YADYLHEDLAIRKFI--QKELA-----EASVSTIEIERAI-N-KVIVSLHTAKPGMVIGKGGANVDALRAQLNKLVH INIIEIKS---PDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRA-GAKGIKTQVSGRLNGADIARAEGYSEGTVPL- -HTLRADIDYAWEEADTTYGKLGVKVWIYMVMTDPIADFLTRIRNANLAKHEVLEV-PASNIKKGIAEILKREGFVKNVE VIE----D---D----KQGIIRVFLKYG---QNG-------E---RVITNLKRISKPGLRVYSKREDVPKVLNGLGIAII STSEGLLTDKEARQKNVGGEVIAYVWMANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRA THKYKDSR-EQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKLRRTLVGRVVSDKMDKTITVIVETKRNHPVYG KRINYSKKYKAHDEK--NIAKEGDIVRIMETRPLSATKHFRLVEVLEEA------------------------------- -MGRSL-KKGPFVDE-HLMKKVEAQAN---DEKKK----VIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQE-DMVGH KLGEFAPTRTYKGHA------A--DDK----KTR------R- >FIRM_Symbiobacterium_thermophilum_IAM_14863 Concatenation of 2 sequences MGIKHYKPTSPGIRQMTRHTFEE-LTST------------RP-EKSLLERLTRKAGRNVYGRITVRH-RGGGHKRM---- YRIIDFK-R--NEFDGIPAKVVSIEYDPNRTCRIAKVVYA-NGAKRYILHPVGLNVGDTVVSGP-D-AD-IKVGNALPLE NIPVGTIVHNIELYPGRGGQLVRSAGASAQIMAK--EGRYALLRLPSGEQRKVLLACRATVGQVGNLEHENIVIGKAGRK -RHL-----GFR-P-AVRGVVMNPVDHPHGGGEGRS-P--IGMPSPVTP---WGKPTLGYKTR-KPNKKSD-R-LIVSRR --------------------------------MQK---G-ILGKKLGMTQIFA-PDGK---------IIPVTVVEAGPCV VVQKK----TTA----T--DGY--NAVQLGF-------GE--IVNK----------PLKGHFK----------------- ---HQ-VKATRYLREFRL--------DDVESL-----NV---GD-VIKA--D-I-FAEGELVDVTGISRGKGFAGGVKRW NFNR-GPSSHGS-KYHRR-PGSLGQRRWA---RVPKGRKLPGRLGGERVTVLGLRVVKVDPEKN---------------- ----------LILIKGA-VPGAKGSLITIR-MPKVAVYN-KEGATV-GEITLSDAVF----GA-EV-NPGLLHEVVQMYL ANKRQGTADTKTRAE--------VS-GGGRKPW---------RQKGTGRAR--------HGS---IR-SP----LW---- RKGGIVFGPH-P-REYGWSMPKKARRAALRQALSAKVKSG----------------E-LIVVDKF----ELE-A------ --PKTRFIV--TAQED--V---NIYKSARNIPGVR-V---------------NAARNLNAYDVLAASK----LVFTQDAV AKVEANLKTKYQQEV----APALQKQFNYKNVMMIPRLEKIVINVGLG-EAVQNAKALDAAVADIAAIAGQRPVITRAKK SISSFKIRTGMPIGCKVTLRGERMWDFLEKLIYVALPRVRDFRGVSP-KSFDGRGNYALGLKEQLLFPEID-----YDKV DKIRGMDVIIVTT-----------------------AKTDEEAKALLKGLGMPFMSRIG-K--APIEIPAGVEVT-V--- -E-G--N-LVRVKGPKGELSREI--HP-A--MSITIEN-GA--LRV---SR-P--SDEREHK-ALHGLTRTLIANMVEGV TKGYSKTLELVGTGY--RAAKTG-NQ--LTLS--VGYSHPVVFNP-P-P-GIEFQVP--A-PNQVIVAG-IDKQLVGQVA ADIRATR------PPEPY---LGKGIKYAGEHIRRKVGK----------MIQVQTRLQVADNTGAKELMCIKVLG-SWRR Y--ANIGDVIVCSVKEASPG-G-------VVKKGDVVRAVVVRTKKGLRREDGSYIRFDENAAVILK-DDKE-PRGTRIF GPVARELR-DKEFMKIISLAPEVLMK-L--HELAPNPGA-RHERKRVG-RGIGSGL-GKTSGRGHKGQKARSGGG-V--- -RPGF-E-GGQMPLTRRLPK-RG--FSNVNVADLVTPELLDET-RVCKVK---------VLG--TGE-L-T-K-A-LTV- RAHAVSESARQKIEAAGGKV-R---VHK--AVAKLNKGRS-KAGNEVVFG----------DYGLQAL--EPAFITDRQIE AARVAMTRFI------KRGGKVWIKIFPHKALTRKPAEVRMGSGK---------GAPEVWVAVVKP-GRILFEL--AG-- VDEETAQEAMRLAAHKLPIKCKF-VRNKARRKRQLRVRKTV---HGTPERPRLNVFRSNQNIYAQIIDD---T--VGRTL VSASTL-DPEV-RSRLQ---GSG-GNKAAAAIVGEVVAKR--ALAAG-VTKVVFDRAGYLYH--GRVAALAEAAREAGLE F--------------------------------------------------------------ME-VKASARFVRIAPRK VRVVIDLVRGKSVNEALALLKFI---------------------------------PKRASEPVAKVIASAAAN----A- EHNF-SLNKDNLYIAKAYVDQGPTLKRYHPRQRGQAFPILKRTSHITVVVKE-MHVKKDEIVVVITGK------DK-GKQ GKVLRVLPKEN--RVV--VEGVNVVKKHTK----PS--AK-NPN-GGIIEMEAPIHASNVM--------------SL--- --AKI-------------------EAK---KAKKKG--------MGQKVHPKGLRIG--IV-KDWDTRWYA------DKR N--FSDLLVEDVKIRKYI--KKTLY-----AAGISRIEIERAG-G-RIRIIVHTAKPGMVIGRQGQGIAELQNQLAQMIS LDVKEIRL---PELDAQLVAESIAQQLEKRMSHRRAMKQAIQRAMRL-GAQGVRIIVSGRIGGAEIARSERAWEGTVPL- -HTLRADIDYGFAEADTTFGKIGVKVWIYMVVSDPIADLLTRIRNANLAYHDRVDV-PGSKMKKAIVQIMKDEGFIRDFE WID----N---G----HQGVIRIYLKYG---PNK-------T---RVISGLRRISKPGLRVYAKRDQIPRVLGGLGIAIL STSKGVMTDKQARQQGLGGEVLCYIWMAKQKIRIRLRAFDHKILDSSAAKIVETAIRTGATVSGPIPLPTEKSIYTILTA PNGEKDIR-EQFEMRTHKRLIDIVEPGSKTVEALMKLDLPAGVDIEIKLRKTRVGVVTSDKMDKTVVVAVETLVQHPLYK KRVRRTKKFKAHDEH--NQCKVGDKVRIMETRPLSKEKRWRVVEIIESA------------------------------- -MGRSL-KKGPYIDP-SVEKKILAMNE---KGEKK----VFKTWARDCTIFPEMVGHTIAVHNGKTHVPVYITE-EMVGH KLGEFAPTRTFRGHG------G--DER----SSR------VR >FIRM_Syntrophomonas_wolfei_wolfei_Goettingen Concatenation of 2 sequences MGIKKFKPTTPSRRHMTTMSFEE-ITKQ------------EP-EKSLIAPLKRKAGRNVKGRITVRH-RGGGHKRQ---- YRIVDFR-R--VK-DNVPARVAAIEYDPNRSAHIALLHYF-DGHKAYIIAPHNLRVGDVIESGP-N-AD-IKTGNTLPLK DIPVGSLIHNIELRPGKGAQLVRSAGAVAQLMAK--EGAYAHVRLPSGEVRLIHVNCRATIGQVGNLEHENMTLGKAGRS -RWL-----GIR-P-GVRGSVMNPTDHPHGGGEGRA-P--IGRKYPVSP---WGKIAIGGKTR-RK-KPSD-N-MIVRKR --------------------------------MTTKKKA-IMGIKIGMTQIFD-ENDK---------AVPVSIIEAGPCT VLQKK----KVE----S--DGY--ESIQVGF-------YN--LANK----------PARGHFK----------------- ---AN-VKPLRYIKEFRI--------DNVDDY-----DV---GQ-EITA--D-I-FTTGDLVDVIGTSKGKGFAGGVKRH NFAR-GSMGHGS-KYHRR-PGSLGA--KGPA-RVFKGRKLPGRLGGERVTVQGLKVVKVYPDRN---------------- ----------LILIKGS-IPGPKRGFVIIK-MPKVALYD-MSGAQV-GEIELNDSVF----GI-KP-NQAVMFDFVKMQL ANKRAGTASSKTRAE--------VR-GGGKKPW---------RQKGTGRAR--------VGS---SR-NP----VW---- TKGGVAFGPR-P-RDFSYRLPRKVRRLAMKSALSSKVLDN----------------N-IVVLDSL----TFD-E------ --PKTRLVV--TAYGD--P---NVIKSARNIPGVK-P---------------LRADFINVYDLLNYDT----LLITREAV ARIEARLYETYKKDI----VPKMMEKFQYDNIMQVPKVERVVVNIGVG-EAIQNPKALDGAVNDLSIISGQKPVITRARK SIAGFKLREGMAIGCKVTLRGERMYDFLDRLINLALPRVRDFRGVSP-QAFDGRGNYSLGIKEQTIFPEID-----YDKI DKIRGLEVVVVTT-----------------------AKTDEEARELLKSMGMPFMSRIG-K--KPISLPAGVEVS-I--- -K-D--N-AISVKGPKGVLEWAL--PE-G--ITVVQEG-NE--LVV---KR-P--SDIKQHR-AMHGLSRALIANMVQGV SAGFEKKLELVGVGY--RAQMQG-KK--LVIS--IGFSHPVEVEP-P-E-GIEFEVP--A-VTRITVKG-IDKQLVGNTA AHIRAIR------KPEPY---KGKGIKYENEVIRRKAGK----------MIQQETMLQVGDNTGAKKVLCVKVLG-STRR Y--ASVGDIIVASVKEASPG-G-------VVKKGDLVKAVVVRTKKEIRRADGSYIAFSENAAVIID-DNNN-PKGTRIF GPVARELR-EKNFMKIISLAPEVLMR-L--EELKAPAGA-NKRTKRVG-RGTGSGH-GKTSTRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLQRRLPK-RG--FNNVNVEDLVNPDTLQET-GLVKVK---------ILG--NGV-L-E-K-R-LQV- KAHKISKQAEEKITAKGGKV-K---QHR--PSL---AGKA-NKGNTITYG----------DYGLQAL--EPAWITNRQIE AARIAINRYV------KRGGKLWIKIFPDRPLTVKPAETRMGKGK---------GSPEHWVAVVKP-GRVMFEL--SG-- VSEEVAREAMRLAAHKLPVKCKF-LKKTLRQGKHKRVRRKV---AGTGERPRLCIFKSLHHIYAQIIDD---E--KGVTL VAASTL-EEGL-KGL-----ESK-TNIAAAQEVGANIAER--AREKG-IIEVVFDRNGYKYH--GSVAALANAAREKGLV F--------------------------------------------------------------ME-ARAIARYIRVSPFK ARQVADLVRGKDTEEAMAILRYT---------------------------------NKKSAPLIRKVLQSAIAN----A- EHNF-DMDSNALVVSQIFIDEGPIVKRMRPRAYGRADVRRHRTSHITVVLRE-MRIKKGDSVLVTTGK------DA-GKK GKVLRVIPDKN--RVV--IEGVNRVKKHQK----PS--RS-LPQ-GGILKIETPLNASNVM-LVCSRC-------NK--P --TRIAHKI---ME--------NGKVR---ICKQCG---EAL--MGQKVHPKGFRIG--II-RDWDSNWYA------D-R D--YSELLHEDVKLRKFI--KDRFY-----AAGISKVEIQRTG-N-RIRVTIHTAKPGIIIGRGGIEVERLKVNLAEMVN INIQEIRR---PEMDAQIVAENVAQQLEKRISFRRAMKQTVGRTMRS-GGIGIKIAISGRLGGAEIARTEWYAEGKVPL- -HTLRADIDYGFAEANTTYGKIGIKVWINMVMTDPVADFLTRIRNGNMVMHETVEV-PGSRIKLSIARIMQEEGYIKDYE FVE----D---G----KQGIIRIYLKYG---PDK-------K---KVITGIKRISKPGLRVYVKKDEIPRVLGGLGTAVI STSKGLMTDKNARKQGLGGEVICYIWNGQQKVRIRLKAFDHKLLDQSSQKIVETARKNGSGVSGPIPLPTEKSIYTILRS PHVNKDSR-EQFEMRTHKRLIDILDPNPRTIDALMHLDLPSGVDIEIKLRKIRIGTVSSDKMDKTITVSVETVKQHPLYK KTIKTSKKYKAHDEN--NEAKTGDIVKIMETRPLSKDKRWRLVEIVQKA------------------------------- -MGRSL-KKGPYCED-KLLKKIELMNQ---SGQKK----VIKTWSRRSTIMPEMIGHTLAVHDGRKHIPVYVTE-DMVGM KLGEFAPTRTYRGHA------G-KSEK----SSR-------- >FIRM_Thermoanaerobacter_pseudethanolicus_ATCC_33223 Concatenation of 2 sequences MGIKSFKPTSPGRRQMTVLTFEE-VTKD------------KP-EKSLVVTLTKTGGRNVYGRITVRH-RGGGHKRK---- YRIIDFK-R--DK-DGIPGKVAAIEYDPNRTAYIALIHYL-DGEKRYIIAPYGLKVGDIIESGE-N-VD-IKVGNALPLR NIPVGTIIHNIELIPGKGGQLVRAAGTAAQLMAK--EGDYVQVRMPSGEIRLIKADCRATIGQVSNLDHENVKIGKAGRS -RWL-----GIR-P-TVRGSAMNPVDHPHGGGEGKA-P--IGHPGPLTP---WGKPALGYKTR-KKGKASD-K-FIIRRR --------------------------------MKK---G-ILGRKHGMTQIFD-EKGE---------VIPVTVIEAGPCV VVQKK----TVE----T--DGY--NAIQVGF-------GD--VLTK----------PLIGHFK----------------- ---AG-VPFKRYLREFRL--------DDISGY-----EV---GS-EIKV--D-I-FKPGDRVDVTGISKGKGFAGVVKRY GANR-GPMSHGS-KYHRR-VGSMGAT-TDPG-RTFKGKIMPGHMGHERVTIQNLEVVKVDPELN---------------- ----------LLLVKGS-VPGPKGSLLIIK-MPKVAVYN-VKGEQV-GEIELKDSVF----GV-PV-NVPVMHEAVLNYL ANQRQGTHSTKTRGE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IKGGIVFGPK-P-RDYSYKLPKKVKRLALKSALSSKVRDN----------------E-IIVLDEF----KLD-Q------ --PKTKLIV--VPEGE--K---NVELSARNIPGVK-T---------------LYANYLNTYDILKYDK----FIITKDAV GIVESRLREKYEKEV----VPALMERFGYKNIMQVPKVEKVVINIGVG-EAKENPKALEAAVDDLTMIAGQKPVITRAKR SIANFKIRKGMPIGVKVTLRGERMYEFMDKLFNIALPRVRDFKGVSP-NSFDGRGNYALGIKEQLIFPEID-----YDKI DKIRGMDIIIVTT-----------------------AKTDEEAKGLLELLGMPFMSRIG-R--LPIEIPKGVEVK-V--- -SPD--N-VVTVKGTKCTLEKKF--PP-I--VNIEVKD-NQ--VIV---TR-N--GDDKEER-AMHGTTRAIIANMVKGV TQGFEKTLEIVGIGY--RAAKQG-KK--LVLN--VGYSHPVEIEEEP---GIEIVVE--G-NNKIIVRG-ADKEKVGQVA ANIRRVR------EPDAY---QGKGIRYAGEVVRLKEGK----------MIQPQTRLKVADNTGAKEIMCIRLEG-SNRK F--SNVGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRTKKGIARKDGTYIRFDDNAAVIIR-DDKQ-PRGTRIF GPVARELR-EKDFMKIISLAPEVLMR-L--HDLKPAEGA-RRERKRVG-RGIGSGH-GKTSGRGQKGQKARSGGG-V--- -RPGF-E-GGQMPLTRRLPK-RG--FTNVNVGTLITPEALIES-GIIKVK---------ILG--DGD-L-N-K-K-FTV- RAHKFSQSAIEKIQAVGGKA-K---QQR--GRI---KGNA-TRGNTLTYG----------EYGLQAL--EPGWITATQIE AARVAMTRFI------KRGGKVWIKIFPDKPVTKKPAETRMGSGK---------GSPEFWVAVVKP-GRVLFEI--AG-- VSEEVAKEALRLAMHKLPIKTKF-LRNELRKRRHLRVRKKV---FGTPERPRLNVFRSLKHIYAQIIDD---T--KGHTL VHASTL-DPEL-RGI-----AKG-ANKQSAKLVGELIAKR--ALEKG-IKDVVFDRGGYIYH--GVVKELADAARQAGLN F--------------------------------------------------------------ME-ARAIARYVRISPRK VRLVLNLIRGKHVDEALTILRFT---------------------------------PKRASGIVAKVLKSAIAN----A- ENNH-GMNRDNLYVAKAVADEGPTMKRVFPRAMGRADIMRKRTSHITIVVKEKLHVKKGDMVVVISGK------DK-GKK GKVLQAFPKEG--KVI--VEGVNIVTKHRK----AT--SP-QKP-GGIIHQEAPIYSSKVM-LYCENC-------GR--G --VRYGVKV---LE--------NGKIR---YCKRCN---ETL--MGQKVHPYGLRVG--VT-QDWLTKWYA------DDK D--FSKLLIEDIKIRNYI--KEKLY-----AAGIPKIVIERAS-N-RIKIDIHAAKPGMVIGKGGAGIDKLREELEKMVI LNIVEVKT---PELSAQLVAENIAAQIEKRISYRRAMKQAIARAMKL-GAKGIKIACSGRLAGAEIARTERYHEGVVPL- -QTLRADIDYGFAEANTTYGKIGVKVWINMVMTDPIADMLTRIRNANIARHETVEI-PASNMKRAIAMIMLKEGFIKSVE EID----D---G----KGGILKLTLKYG---PNK-------E---RVISGLKRISKPGLRVYARHDELPRVLGGLGIAII STSKGIMTDKEARKAGVGGEVICYIWMPKQKIRIRLKAFDHAILDQSAQKIVETAKRTGAEVSGPIPLPTEKDIITILRA PHKYKDSR-EQFEIRTHKRLIDILNPTPKTVDALMRLDLPSGVDIEIKLRKVRIGTVVSNKMQKTIVVAVEDRVRHPLYG KTIKRTKKFKVHDEN--NVCNVGDIVKIMETRPLSKEKRWRLVEIVKRA------------------------------- -MSRSV-KKGPYVDP-KLLKKIVEMNK---KNEKK----VIKTWSRSSTIVPEMVGHTIAVHDGRKHVPVYITE-AMVGH KLGEFAPTRTFHGHA----------DTEKTSKVK-------- >FIRM_Thermoanaerobacter_sp_X514 Concatenation of 2 sequences MGIKSFKPTSPGRRQMTVLTFEE-VTKD------------KP-EKSLVVTLTKTGGRNVYGRITVRH-RGGGHKRK---- YRIIDFK-R--DK-DGIPGKVAAIEYDPNRTAYIALIHYL-DGEKRYIIAPYGLKVGDIIESGE-N-VD-IKVGNALPLR NIPVGTIIHNIELIPGKGGQLVRAAGTAAQLMAK--EGDYVQVRMPSGEIRLIKADCRATIGQVSNLDHENVKIGKAGRS -RWL-----GIR-P-TVRGSAMNPVDHPHGGGEGKA-P--IGHPGPLTP---WGKPALGYKTR-KKGKASD-K-FIIRRR --------------------------------MKK---G-ILGRKHGMTQIFD-EKGE---------VIPVTVIEAGPCV VVQKK----TVE----T--DGY--NAIQVGF-------GD--VLTK----------PLIGHFK----------------- ---AG-VPFKRYLREFRL--------DDISGY-----EV---GS-EIKV--D-I-FKPGDRVNVTGISKGKGFAGVVKRY GANR-GPMSHGS-KYHRR-VGSMSAT-TDPG-RTFKGKIMPGHMGHERVTIQNLEVVKVDPELN---------------- ----------LLLVKGS-VPGPKGSLLIIK-MPKVAVYN-VKGEQV-GEIELKDSVF----GV-PV-NVPVMHEAVLNYL ANQRQGTHSTKTRGE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IKGGIVFGPK-P-RDYSYKLPKKVKRLALKSALSSKVRDN----------------E-IIVLDEF----KLD-Q------ --PKTKLIV--VPEGE--K---NVELSARNIPGVK-T---------------LYANYLNTYDILKYDK----FIITKDAV GIVESRLREKYEKEV----VPALMERFGYKNIMQVPKVEKVVINIGVG-EAKENPKALEAAVDDLTMIAGQKPVITRAKR SIANFKIRKGMPIGVKVTLRGERMYEFMDKLFNIALPRVRDFKGVSP-NSFDGRGNYALGIKEQLIFPEID-----YDKI DKIRGMDIIIVTT-----------------------AKTDEEAKGLLELLGMPFMSRIG-R--LPIEIPKGVEVK-V--- -TPD--N-VVTVKGSKGTLEKKF--PP-I--VNIEVKD-NQ--VIV---TR-K--GDDKEEK-AMHGTTRAIIANMVKGV TEGFEKALEIVGIGY--RAAKQG-KK--LVLN--VGYSHPVEIEEKP---GIEIIVE--G-NNKIIVRG-IDKEKVGQVA ANIRRVR------EPDAY---QGKGIRYAGEVVRLKEGK----------MIQPQTRLKVADNTGAKEIMCIRLEG-SNRK F--SNVGDVIVASVKSATPG-G-------VVKKGEVVKAVIVRTKKGIARKDGTYIRFDDNAAVIIR-DDKQ-PRGTRIF GPVARELR-EKDFMKIISLAPEVLMR-L--HDLKPAEGA-RRERKRVG-RGIGSGH-GKTSGRGQKGQKARSGGG-V--- -RPGF-E-GGQMPLTRRLPK-RG--FTNVNVGTLITPEALIES-GIIKVK---------ILG--DGD-L-N-K-K-FTV- RAHKFSQSAIEKIQAVGGKA-K---QQR--GRI---KGNA-TRGNTLTYG----------EYGLQAL--EPGWITATQIE AARVAMTRFI------KRGGKVWIKIFPDKPVTKKPAETRMGSGK---------GSPEFWVAVVKP-GRVLFEI--AG-- VSEEVAKEALRLAMHKLPIKTKF-LRNELRKRRHLRVRKKV---FGTPERPRLNVFRSLKHIYAQIIDD---T--KGHTL VHASTL-DPEL-RGI-----AKG-ANKQSAKLVGELIAKR--ALEKG-IKDVVFDRGGYIYH--GVVKELADAARQAGLN F--------------------------------------------------------------ME-ARAIARYVRISPRK VRLVLNLIRGKHVDEALTILRFT---------------------------------PKRASGIVAKVLKSAIAN----A- ENNH-GMNRDNLYVAKAVADEGPTMKRVFPRAMGRADIMRKRTSHITIVVKEKLHVKKGDMVVVISGK------DK-GKK GKVLQAFPKEG--KVI--VEGVNIVTKHRK----AT--SP-QKP-GGIIHQEAPIYSSKVM-LYCENC-------GR--G --VRYGVKV---LE--------NGKIR---YCKRCN---ETL--MGQKVHPYGLRVG--VT-QDWLTKWYA------DDK D--FSKLLIEDIKIRNYI--KEKLY-----AAGIPKIVIERAS-N-RIKIDIHAAKPGMVIGKGGAGIDKLREELEKMVI LNIVEVKT---PELSAQLVAENIAAQIEKRISYRRAMKQAIARAMKL-GAKGIKIACSGRLAGAEIARTERYHEGVVPL- -QTLRADIDYGFAEANTTYGKIGVKVWINMVMTDPIADMLTRIRNANIARHETVEI-PASNMKRAIAMIMLKEGFIKSVE EID----D---G----KGGILKLTLKYG---PNK-------E---RVISGLKRISKPGLRVYARHDELPRVLGGLGIAII STSKGIMTDKEARKAGVGGEVICYIWMPKQKIRIRLKAFDHAILDQSAQKIVETAKRTGAEVSGPIPLPTEKDIITILRA PHKYKDSR-EQFEIRTHKRLIDILNPTPKTVDALMRLDLPSGVDIEIKLRKVRIGTVVSNKMQKTIVVAVEDRVRHPLYG KTIKRTKKFKVHDEN--NVCNVGDIVKIMETRPLSKEKRWRLVEIVKRA------------------------------- -MSRSV-KKGPYVDP-KLLKKIVEMNK---KNEKK----VIKTWSRSSTIVPEMVGHTIAVHDGRKHVPVYITE-AMVGH KLGEFAPTRTFHGHA------DTEKTS----KVK-------- >FIRM_Thermoanaerobacter_tengcongensis_MB4 Concatenation of 2 sequences MGIKAYKPTSPGRRQMTVLTFEE-ITKK------------EP-EKSLLAPLTKKAGRNVYGRITVRH-RGGGHKRR---- YRIIDFK-R--DK-DGIPGKVAAIEYDPNRTAFIALIHYA-DGEKRYIIAPHGLKVGDIVESGE-N-VD-IKVGNALPLR NIPVGTIVHNIELIPGKGGQLVRAAGAAAQLMAK--EGDYVHIRMPSGEIRLINANCRATIGQVSNIDHENVKIGKAGRS -RWL-----GIR-P-TVRGSAMNPVDHPHGGGEGKA-P--IGHPGPLTP---WGKPALGYKTR-KKGKASD-K-FIVKRR --------------------------------MKK---G-ILGKKHGMTQIFD-EKGE---------VIPVTVIEAGPCV VVQKK----TVE----K--DGY--NAIQVGF-------GD--VLNK----------PLLGHFK----------------- ---AG-VSPKRYLREFRL--------DDISGY-----EV---GT-EIKV--D-I-FKPGDRVDVTGISKGKGFAGVIKRY GARR-GPMSHGS-KYHRR-VGSMGAT-TDPG-RTFKGKKMPGRMGSDRVTIQNLEVVKVDPELN---------------- ----------LLVVKGS-VPGPKGSLLIIR-MPKVPVYN-VKGEQV-GEIELKDSVF----GV-PV-NVAVMHQAVVNYL ANQRQGTHSTKTRGE--------VR-GGGRKPW---------RQKGTGRAR--------QGS---IR-AP----QW---- IKGGVVFGPK-P-RDYSYKLPKKVKRLALKSALSSKVRDN----------------E-IIVLDEF----KLE-Q------ --PKTKLIV--VPQGE--K---NVELSARNMPNAK-A---------------LYANLLNTYDVLKYEK----FIITKDAV AIVESRLREKYEKEV----VPALMERFGYKNIMQVPKLEKVVINIGVG-EAKENPKALEAAMNDLMMISGQKPVITRAKK SISNFKIRKGMPIGVKVTLRRERMYEFLDKLFNIALPRVRDFKGVSP-NSFDGRGNYALGVREQLIFPEID-----YDKI DKVRGMDIIIVTT-----------------------AKTDEEAKALLELLGMPFMSRIG-R--LPIPIPKGVEVK-V--- -SPD--N-VVTVKGAKGTLEKKF--PP-I--VNIEVRD-GE--VVV---TR-K--GDDKEER-AMHGTTRAIIANMVKGV TEGFEKALEIVGVGY--RAAKQG-KK--LILN--VGYSHPVEIEEEP---GIEIIVE--G-NNRIIVRG-ADKERVGQVA ANIRRVR------EPDAY---QGKGIRYVGEVVRLKEGK----------MIRPQTRLKVADNTGAKEIMCIRLLG-SNRK Y--SNVGDIIVASVKSATPG-G-------VVKKGEVVKAVIVRTKKGIARKDGTYIRFDDNAAVIIR-DDKQ-PRGTRIF GPVARELR-DKDFMKIISLAPEVLMR-L--HDLKPAEGS-TKKKKRVG-RGIGSGH-GKTSGRGHKGQNARSGGG-V--- -RPGF-E-GGQMPLTRRIPK-RG--FTNVNVGTLITPEVLIEK-GIIKVK---------ILG--DGE-L-T-K-K-LTV- KAHKFSQSAVEKIQAVGGKA-K---QQR--GRI---KGNA-TRGNTLTYG----------EYGLQAL--EPGWITATQIE AARVAMTRYI------KRGGKVWIKIFPDKPVTKKPAETRMGSGK---------GSPEFWVAVVKP-GRVLFEI--GG-- VSEDVAKEALRLAMHKLPIKTKF-LRNELRKKRHLRVRKKV---FGTPERPRLNVYKSLKHIYAQIIDD---T--KGHTL VSASTL-DPEL-RDV-----AKG-ANKQSAKLVGELIAKR--ALEKG-IKDVVFDRGGYLYH--GVVKELADAARQAGLN F--------------------------------------------------------------ME-ARAIARYVRISPRK ARLVLNLIRGKHVDEALAILKFT---------------------------------PKKASKIVEKVLKSAIAN----A- ENNH-NMNRDNLYVAKAVADEGPTMKRVLPRAMGRADIMRRRTSHITIVVKEKLHVKKGDMVVVISGK------DK-GKK GRVLQAFPKEG--KVI--VEGVNVVTKHRK----AT--RP-QKP-GGIIHQEAPIHSSKVM-LYCENC-------GR--G --VRYGIKI---LE--------NGKVR---YCKRCN---ETL--MGQKVHPYGLRVG--VT-KDWLAKWYA--------K DKDFPNILVEDIKIRNYI--KEKLY-----AAGIPQIVIERAS-N-RIKIDIYAAKPGMVIGKGGTGVDRLREELEKMVI LNIIEVKT---PELSAQLVAENIAAQIEKRISYRRAMKQAIARAMKL-GAKGIKIACSGRLAGAEIARTERYHEGVVPL- -QTLRADIDYGFAEANTTYGKIGVKVWINMVMTDPIADMLTRIRNANLARHETVEI-PSSKMKKAIAMILLKEGFVKAVE EID----D---G----KGGILKITLKYG---PNK-------E---RVISGLKRISKPGLRVYAKHDELPRVLGGLGIAII STSKGIMTDKEARKAGLGGEVICYVWMPKQKIRIRLKAFDHAILDQSAQKIVETAKRTGAEVSGPIPLPTKREVITILRA PHKYKDSR-EQFEIKTHKRLIDILNPTPKTVDALMKLDLPSGVDIEIKLRKVRIGTVVSNKMQKTIVVAVEDKFRHPLYG KIVKRTKKYKVHDEN--NICNVGDVVKIMETRPLSKEKRWRLVEVIKKA------------------------------- -MSRSV-KKGPFVDP-KLLKKIIEMNK---KNEKK----VIKTWSRDSTIVPEMVGHTIAVHDGRKHVPVYITE-AMVGH KLGEFAPTRTFRGHA------G--SEK----TTK------VK >GAMMA_Acidithiobacillus_ferrooxidans_ATCC_23270 Concatenation of 2 sequences MALIKTKPTSAGRRFVVKTIDTR-LHKG------------NP-HSALVEVQSHSGGRNNLGRVTRRH-QGGGHKSH---- YRLVDFK-R--NK-LDIPGKVERLEYDPNRSAHIALICYV-DGERRYILAAKGMSVGDPVLSAE-Q-TP-IKPGNCMPLR GIPVGSVVHNVEMRPGKGGQIARSAGASVQLMAR--EGDYAQLRLRSGEVRRIHVSCRATIGEVGNEEHGSRQLGKAGAT -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGQPTKGYRTR-RNKRTSN---MIVRRR --------------------------------MVM---G-LIGRKVGMTRIVA-GDGR---------VLPVTVIHVAPNT VAQVK----DIA----T--DGY--CAVQVAT-------GT--RVTS----------ALAGHFK----------------- ---NG-IAPGRLLREFRV--------ADTANY-----AC---GM-DIDL--D-I-FAEGQRVDVSGVSKGKGFAGAIKRH NFRS-NRASHGNSLSHRA-PGSIGCR-QTPG-RVFKGKKMAGHLGAEQVTTLNLELVRIDANRR---------------- ----------LLMIKGA-VPGARDGDVMIR--MQVQSLE-VTTGKS-SEIEIADGVF----GV-PY-NEALLHQVVVAQM AGMRSANAVQKNRAA--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----IW---- RGGGRAFPGG-N-ENYTQKVNKKMWAGAMRTVLAELLRQG----------------R-LQIIQQE----DFG-E------ --PRSRLLV--MGEVP--L---NLFLGLRNFPRVG-I---------------AGWQDVGPADLLQYGR----VLLDVEAA ARLGARLHALYKTSI----APKLMQEFGFSSVMEVPKLLKITLNMGVG-EAVGDKKVLEAAVGDMTRIAGQKPVVTRARK SVAAFKIRDGYPIGCMVTLRGIVMYEFLDRLVSVAIPRIRDFRGLSP-KSFDGRGNYTMGVKEQIIFPEIE-----YDKI DRLRGLDVVFTTT-----------------------AKNDEEGLGLLKAFKMPFMSRVA-K--QPVPLPKGVEVH-V--- -A-D--Q-RLVVKGPKGEMSVPF--HP-A--VELRIDD-GG--ASL---------TWSDNQN-AQAGTMRAILNNMVQGV SQGYEQKLEIIGVGY--RAQAKG-KT--LSLS--LGFSHPVDYSV-P-D-DITIETP--T-QTEIVIRG-IDKQKIGQIA ADIRAYR------PPEPY---KGKGVRYAGENVRRKEAK----------MIQTQTRLNVADNSGAREVMCIKVLG-SHRR Y--ADIGDVIKVSIKDAVPR-G-------KVKKGDVYNALVVRTRKGVRREDGSLIRFDSNAAVLLN-NQLQ-PIGTRIF GPVTRELR-GANFMKIISLAPEVLMK-L--NTIAPAEGS-KKDRRRVG-RGIGSGF-GKTAGRGHKGQHARSGGY-H--- -KVGF-E-GGQMPLQRRIPK-RG--FRNVALSQLVDLEGLLLR-RIVRVK---------VIL--TGE-I-T-Q-G-LTV- RGLRVSAGARAAIEKAGGKV-K---QHK--GRN---RGVA-TRGSKVSFG----------EFGLKAV--GRGRITARQLE AARRAISRHV------KRGGRIWIRIFPDKPISKKPAEVRMGKGK---------GNPEYWVALIQP-GKVLYEM--EG-- VTEEVAREAFALGAAKLPVQTAF-VKNLARLRRARKTRARI----ASQAKPRLCVFRSGRHIYAQVIDD---S--QGKVL AQASTV-EGEL-RASM----GRG-ADVAAAATIGQRVAAK--ALAVG-VKEVAFDRSGYRYH--GRVRALADAAREGGLS F--------------------------------------------------------------MK-SSAVLKGLQMSPQK ARLVADLVRGQPVGKALEILRFT---------------------------------TKKAALPIRKCLESAIAN----A- ENNE-GADVDALVVEQIMIDGGAVLKRFAARAKGRGSRILKRTSHITVVVAEMLKVRKDDEVVVLAGK------DK-GKR GKVLKVLREDS--RVL--VEKVNMIKRHVR----PD--RM-GKA-GGIVEKEAPIHVSNVA-IFNAAT-------GG--G --DRIGYKV---LE--------DGKVR---VFKSNG---EVIP-MGQKTNPIGLRLG--II-KNWNSRWYG------K-S D--FQEKLLEDIKVRQFI--RERLA-----GGAVSDIIIERPA-R-SARITVHTARPGIVIGKKGEDIEKLRHDVQKRVH INVEEIRK---PELDAQLVAESVAQQLVRRIMFRRAMKRAVTNAMRF-GALGMRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGFAEANTTYGIIGVKVWIFMSVTDPIADMLTRIRNAQQVNKAKVRM-PASKLKRAIARVLVEEGYIQEVK EDV----A---N----GHPVLDLTLKYY----AG-------A---GVIAEIRRVSRPGVRVYRGAEDLPRVRDGFGIAII STSQGIMTDRAARSAGIGGEVLCVVSMDSSKIRIRLKSYDYRMLDISAAEIVETARRTGARVCGPIPLPTKIERFTVLRS PHVDKNAR-DQFEQRTHKRLLDILDPNDKTVDALIKLDLAAGVDVEIKL-RSLVGTVVSNLMDKSIVVNVERRIQHPLYK KYIRRSKKFHAHDAE--NICHIGDIVKIEECRPLSKTKSWRLVSVLAEG------------------------------- -MPRSI-KKGPFIDE-HLDRKVQSAQA---SNSRR----PIKTWSRRSTITPDFIGLTISVHNGRQHIPVVVNE-NMVGH KLGEFALTRTFKGHV------A---DK----KAK------R- >GAMMA_Acinetobacter_baumannii_AB307-0294 Concatenation of 2 sequences MPIQKCKPTSPGRRFVEKVVHDH-LHKG------------AP-YAPLVEAKKRTGGRNNNGHITTRH-VGGGHKQH---- YRIVDFK-R--NK-DGVPAVVERIEYDPNRTAHIALLKYA-DGERRYIIAPKGLRAGDKVQSGN-D-AP-IRPGNCLPLR NMPIGSTLHNVELKIGKGAQLARSAGASVQLLGR--DGSYAIIRLRSGEMRKVHVECRAVIGEVSNQENNLRSLGKAGAA -RWR-----GVR-P-TVRGMAMNPIDHPHGGGEGRN----KGIQ-PVSP---WGQKAKGYKTR-TNKRTTK---MIIRDR --------------------------------MAI---G-LVGRKCGMTRIFT-DAGV---------SVPVTVIEVDPNR ITQIK----TLE----T--DGY--QAVQVTT-------GE--RVTN----------AQKGHFK----------------- ---AG-VAAGRLVKEFRV------TEAELEGR-----EV---GG-TIGV--D-L-FTVGQIVDVTGQSKGKGFQGGVKRW NFRT-QDATHGNSVSHRV-LGSTGQN-QTPG-RVFKGKKMAGHLGDERVTVQGLEIVSVDTERS---------------- ----------VLVVKGA-IPGATGGDVIVR----MNLKT-VSG----SAVELSEVAF----GR-EF-NEALVHQVVTAYL AGGRQGTRAHKSRAD--------VS-GGGKKPF---------RQKGTGRAR--------AGS---IR-SP----IW---- VGGGKTFAAR-P-QDWSQKVNRKMYRGAMQCILAELVRQD----------------R-LVLVEEF----AVA-A------ --PKTKLIV--TDAVD--E---NLYLAARNLPHVD-V---------------VDATAIDPVSLIAFDK----VVMSVAAA KKIEARLKARYNDEL----KAKLQEELSIKNVMEIPRITKITLNMGVG-AAATDKKLLDGAVADMQLIAGQKPVVTLARK SIAGFKIRDGWPIGCKVTLRGDQMYEFLDRLISIAIPRIRDFRGFSA-KSFDGRGNYSMGLKEQIVFPEID-----FDKI DRIRGMDITITTT-----------------------ARTDDEGRALMRAFGFPFMSRVA-K--APVTVPNGVTVT-Q--- -N-G--R-QVEVKGSKGTLSFNL--HA-L--VELKQEE-GK--LQL----A-P-AKESKDAW-MQAGTARAVLNNLVKGV SEGFERKLQLVGVGY--KAAVKG-TV--VNLN--LGYSHPIDYAL-P-E-GVTAETP--T-ATEIILKS-ANKQLLGQVA AEIRAYR------SPEPY---KGKGVRYSDEVILRKEAK----------MIQTETMLDVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIKVTVKEAIPR-A-------RVKKGDVMNAVVVRTKFGIRRPDGSVIRFDDNAAVILN-NNKA-PIATRIF GPVTRELR-TEQFMKIISLAPEVLLR-L--NELAPAEGA-KREHRRLG-RGIGSGV-GKTGGRGIKGQKSRKSGG-V--- -RPGF-E-GGQTAIYRRLPK-FG--FTSVRLSELVSLETLKAA-NVVRAR---------IVL--SGE-I-T-R-A-FTV- QGVALTKGAKAAIEAAGGKV-K---VHK--GRN---TGLA-HRGSTVSFG----------SIAIKAT--ERGRMTARQIE AARRTISRRI------KRGGKIFIRVFPDKPITEKPLEVRMGNGK---------GNVEYWVCEIKP-GKILYEI--EG-- VNEDLAREAFALAAAKLPFKTTI-VKKQSRLRRAKSTRLHI----RALGATRLCVNRTPRHIYAQVISA---D--GGKVL AQASTL-DASL-RS------GTT-GNIEAATKVGALIAER--AKAAG-VTKVAFDRSGFKYH--GRIKALADAAREGGLE F--------------------------------------------------------------ME-VTAKLRGAAISAQK ARLVADLIRGKSVAHALNILNFS---------------------------------NKKAAVLVKKALESAIAN----A- EHNN-SLDVDDLKVSTIYVDEGMSLKRIMPRAKGRADRITKRTCHITVKVGVMAKIKKGDQVIVIAGK------EK-GKQ GTVLSVSEDRV--K----VEGLNLVKKHQK----PN--RVTGAE-GGIVTQEASLHISNVA-ILNATT-------QK--A --DRVGYQV----I--------DGKTR---VYKSTG---ESV--MGQKVHPIGIRLG--VV-KRHNANWYA------NPK Q--YAEYLLKDLQVREFL--TKKLK-----NAMVSNILIERPS-G-AAKVTISTARPGIVIGKKGEDIEKLQRELTNIAQ VSINEIDR---PDLDARLVAEAIASQLEKRVMFRRAMKRAVQNTMRA-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATMRAETTYGTIGVKVWIFMSMQDTVADMLTRVRNAQMAKKQTVSM-PSSKLKVAIANVLQQEGYISNVE VAQ----E---E----TKSTLTITLKYF----EG-------K---PVIEMVKRVSRPGLRQYRGKDKLPSVKQGLGIAIV STSKGIMTDRAARAAGIGGEVIAFVSMSNQRIRIRLKSFDHRLIDQSAQEIVETAKRTGAQVCGPIPMPTRIERFNVLTS PHVNKDAR-DQYEIRTYKRLIDIVQPTDKTVDALMKLDLAAGVDVQIALVRTLTGKVVSDKMDKSIVVLIERRVQHPLYG KSIRRSTKLHAHDEN--NVAKIGDVVTIKESRPISKTKAWTLVEVVEAA------------------------------- -MPRSL-KKGPFVDA-HLFAKVEAAVA---SNSRK----PIKTWSRRSMILPDFVGLTISVHNGRNHVPVIVTE-HMVGH KLGEFAPTRTYRGHG------V---DK----KSK------R- >GAMMA_Acinetobacter_baumannii_SDF Concatenation of 2 sequences MPIQKCKPTSPGRRFVEKVVHDH-LHKG------------AP-YAPLVEAKKRTGGRNNNGHITTRH-VGGGHKQH---- YRIVDFK-R--NK-DGVPAVVERIEYDPNRTAHIALLKYA-DGERRYIIAPKGLRAGDKVQSGN-D-AP-IRPGNCLPLR NMPIGSTLHNVELKIGKGAQLARSAGASVQLLGR--DGSYAIIRLRSGEMRKVHVECRAVIGEVSNQENNLRSLGKAGAA -RWR-----GVR-P-TVRGMAMNPIDHPHGGGEGRN----KGIQ-PVSP---WGQKAKGYKTR-TNKR-TT-K-MIIRDR --------------------------------MAI---G-LVGRKCGMTRIFT-DAGV---------SVPVTVIEVDPNR ITQIK----TLE----T--DGY--QAVQVTT-------GE--RVTN----------AQKGHFK----------------- ---AG-VAAGRLVKEFRV------TEAELEGR-----EV---GG-TIGV--D-L-FTVGQIVDVTGQSKGKGFQGGVKRW NFRT-QDATHGNSVSHRV-LGSTGQN-QTPG-RVFKGKKMAGHLGDERVTVQGLEIVSVDTERS---------------- ----------VLVVKGA-IPGATGGDVIVR----MNLKT-VSG----SAVELSEVAF----GR-EF-NEALVHQVVTAYL AGGRQGTRAHKSRAD--------VS-GGGKKPF---------RQKGTGRAR--------AGS---IR-SP----IW---- VGGGKTFAAR-P-QDWSQKVNRKMYRGAMQCILAELVRQD----------------R-LVLVEEF----AVA-A------ --PKTKLIV--TDAVD--E---NLYLAARNLPHVD-V---------------VDATAIDPVSLIAFDK----VVMSVAAA KKIEARLKARYNDEL----KAKLQEELSIKNVMEIPRITKITLNMGVG-AAATDKKLLDGAVADMQLIAGQKPVVTLARK SIAGFKIRDGWPIGCKVTLRGDQMYEFLDRLISIAIPRIRDFRGFSA-KSFDGRGNYSMGLKEQIVFPEID-----FDKI DRIRGMDITITTT-----------------------ARTDDEGRALMRAFGFPFMSRVA-K--APVTVPNGVTVT-Q--- -N-G--R-QVEVKGSKGTLSFNL--HA-L--VELKQEE-GK--LQL----A-P-AKESKDAW-MQAGTARAVLNNLVKGV SEGFERKLQLVGVGY--KAVVKG-TV--VNLN--LGYSHPIDYAL-P-E-GVTAETP--T-ATEIILKS-ANKQLLGQVA AEIRAYR------SPEPY---KGKGVRYSDEVILRKEAK----------MIQTETMLDVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIKVTVKEAIPR-A-------RVKKGDVMNAVVVRTKFGIRRPDGSVIRFDDNAAVILN-NNKA-PIATRIF GPVTRELR-IEQFMKIISLAPEVLLR-L--NELAPAEGA-KREHRRLG-RGIGSGV-GKTGGRGIKGQKSRKSGG-V--- -RPGF-E-GGQTAIYRRLPK-FG--FTSVRLSELVSLETLKAA-NVVRAR---------IVL--SGE-I-T-R-A-FTV- QGVALTKGAKAAIEAAGGKV-K---VHK--GRN---TGLA-HRGSTVSFG----------SIAIKAT--ERGRMTARQIE AARRAISRRI------KRGGKIFIRVFPDKPITEKPLEVRMGNGK---------GNVEYWVCEIKP-GKILYEI--EG-- VNEDLAREAFALAAAKLPFKTTI-VKKQSRLRRAKSTRLHI----RALGVTRLCVNRTPRHIYAQVISA---D--GGKVL AQASTL-DASL-RS------GTT-GNIEAATKVGALIAER--AKAAG-VTKVAFDRSGFKYH--GRIKALADAAREGGLE F-------------------------------------------------------------MME-VTAKLRGAAISAQK ARLVADLIRGKSVAHALNILNFS---------------------------------NKKAAVLVKKALESAIAN----A- EHNN-SLDVDDLKVSTIYVDEGMSLKRIMPRAKGRADRITKRTCHITVKVGVMAKIKKGDQVIVIAGK------EK-GKQ GTVLSVSEDRV--K----VEGLNLVKKHQK----PN--RVTGAE-GGIVTQEASLHISNVA-ILNATT-------QK--A --DRVGYQV----I--------DGKTR---VYKSTG---ESV--MGQKVHPVGIRLG--VV-KRHNANWYA------NPK Q--YAEYLLKDLQVREFL--TKKLK-----NAMVSNILIERPS-G-AAKVTISTARPGIVIGKKGEDIEKLQRELTNIAQ VSINEIDR---PDLDARLVAEAIASQLEKRVMFRRAMKRAVQNTMRA-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATMRAETTYGTIGVKVWIFMSMQDTVADMLTRVRNAQMAKKQTVSM-PSSKLKVAIANVLQQEGYISNVE VAQ----E---E----TKSTLTITLKYF----EG-------K---PVIEMVKRVSRPGLRQYRGKDKLPSVKQGLGIAIV STSKGIMTDRAARAAGIGGEVIAFVSMSNQRIRIRLKSFDHRLIDQSAQEIVETAKRTGAQVCGPIPMPTRIERFNVLTS PHVNKDAR-DQYEIRTYKRLIDIVQPTDKTVDALMKLDLAAGVDVQIALVRTLTGKVVSDKMDKSIVVLIERRVQHPLYG KSIRRSTKLHAHDEN--NVAKIGDVVTIKESRPISKTKAWTLVEVVEAA------------------------------- -MPRSL-KKGPFVDA-HLFAKVEAAVA---SNSRK----PIKTWSRRSMILPDFVGLTISVHNGRNHVPVIVTE-HMVGH KLGEFAPTRTYRGHG------V---DK----KSK------R- >GAMMA_Acinetobacter_sp_ADP1 Concatenation of 2 sequences MPIQKCKPTSPGRRFVEKVVHSH-LHKG------------KP-FAALVEAKKRTGGRNNNGHITTRH-VGGGHKQH---- YRLVDFK-R--NK-DGIPAVVERIEYDPNRTAHIALLKYA-DGERRYIIAPKGLRAGDKVQSGN-D-AP-IRPGNCLPLR NMPIGSTLHNVELKIGKGAQLARSAGTSVQLLGR--DGSYAIVRLRSGEMRKIHVECRAVIGEVSNQENNLRSLGKAGAS -RWR-----GVR-P-TVRGMAMNPVDHPHGGGEGRN----KGIQ-PVSP---WGQKAKGYKTR-TNKR-TT-K-MIIRDR --------------------------------MAI---G-LVGRKCGMTRIFT-DAGV---------SVPVTVIEVDPNR ITQIK----TLE----T--DGY--QAVQVTT-------GE--RVTN----------AQKGHFK----------------- ---AG-VAAGRLVKEFRV------TEAELEGR-----EI---GG-TIGV--D-L-FTVGQVVDVTGQSKGKGFQGGVKRW NFRT-QDATHGNSVSHRV-LGSTGQN-QTPG-RVFKGKKMAGHLGDERVTVQGLEIVSIDAERS---------------- ----------VLVVKGA-IPGATGGDVIVRRGNNVNLKT-VSG----SAVELSEVAF----GR-EF-NEALVHQVVTAYL AGGRQGTRAQKSRAE--------VS-GGGKKPF---------RQKGTGRAR--------AGS---IR-SP----IW---- VGGGKTFAAR-P-QDWSQKVNRKMYRGAMQCILAELVRQD----------------R-LVLVEEF----AVA-A------ --PKTKLIV--TDAVD--E---NLYLAARNLPHVD-V---------------VDATAIDPVSLIAFDK----VVMSVAAA KKIEARLKTRYNEEL----KAKLQQELGIKNVMEIPRITKITLNMGVG-AAATDKKLLDGAVADMQLIAGQKPVVTLARK SIAGFKIRDGWPIGCKVTLRGEQMYEFLDRLISIAIPRIRDFRGFSS-KSFDGRGNYSMGLKEQIVFPEID-----FDKI DRIRGMDITITTT-----------------------ARTDDEGRALMRTFGFPFMSRVA-K--APVTVPNGVAVT-Q--- -N-G--R-QVEVKGTKGTLSFNL--HA-L--VELKQEE-GK--LQL----A-P-VKESKDAW-MQAGTARAVLNNLVKGV SEGFERKLQLIGVGY--KAAVKG-TS--INLN--LGFSHPIDYSL-P-E-GVTAETP--T-ATEIILKS-ADKQLLGQVA SEIRGYR------PPEPY---KGKGVRYSDEVVLRKEAK----------MIQTESMLDVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIKVTVKEAIPR-G-------RVKKGDVMNAVVVRTKFGIRRPDGSVIRFDDNAAVLLN-NNKA-PIATRIF GPVTRELR-TEQFMKIISLAPEVLLR-L--NELAPAEGA-KRDNRRLG-RGIGSGV-GKTGGRGVKGQKSRKSGG-V--- -RPGF-E-GGQTAIYRRLPK-FG--FTSVRLSELVSLETLKAA-NVVRAR---------VVL--SGE-V-T-R-A-FTV- QGVALTKGAQAAIEAAGGKV-K---VQK--GRN---TGLA-HRGSTVSFG----------SIAIKAT--ERGRMTARQIE AARRTISRRI------KRGGKIFIRVFPDKPITEKPLEVRMGNGK---------GNVEYWVCEIKP-GKILYEI--EG-- VNDELATQAFKLAAAKLPFKTTI-VKKQSRLRRAKSTRLHI----RALGATRLCVNRTPRHIYAQVISA---D--GGKVL AQASTL-DTSL-RS------GTT-GNVEAATKVGALIAER--AKAAG-VTKVAFDRSGFKYH--GRIKALADAAREGGLE F-------------------------------------------------------------MME-VTAKLRGAAISAQK ARLVADLIRGKSVAHALNILNFS---------------------------------NKKAAVLVKKALESAIAN----A- EHNN-SLDVDDLKVSTIYVDEGISLKRIMPRAKGRADRITKRTCHITVKVGVMAKIKKGDQVIVIAGK------EK-GKQ GTVLSVSEDRV--K----VEGLNLVKKHQK----PN--RVTGAE-GGIVTQEASLHISNVA-VFNATT-------QK--A --DRVGYQV---DE--------NGKTR---VYKSNG---ESV--MGQKVHPIGIRLG--VV-KRHNANWYA------NPK Q--YAEYLLKDLQVREFL--TKKLK-----SAMVSNILIERPT-G-AAKVTISTARPGIVIGKKGEDIEKLQRELTNIAQ VSINEIDR---PDLDARLVAEAIASQLEKRVMFRRAMKRAVQNSMRA-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATMRAETTYGTIGVKVWIFMSMQDTVADMLTRVRNAQMAKKQTVSM-PSSKLKVAIANVLQQEGYISNVE VAQ----E---E----AKATLTLTLKYF----EG-------K---PVIETVKRVSRPGLRQYRGKDKIPSVKQGLGIAIV STSKGIMTDRAARAAGIGGEVIAFVSMSNQRIRIRLKSFDHRLIDQSSQEIVETAKRTGAQVCGPIPMPTRIERFNVLTS PHVNKDAR-DQYEIRTYKRLIDIVQPTDKTVDALMKLDLAAGVDVQIALVRTLTGKVVSDKMDKSIVVLIERRVQHPLYG KSIRRSTKLHAHDEN--NVAKLGDLVTIKESRPISKTKAWTLVEVVEVA------------------------------- -MPRSL-KKGPFVDA-HLFAKVEAAVA---ANNRK----PIKTWSRRSMILPDFVGLTISVHNGRNHVPVIVTE-HMVGH KLGEFAPTRTYRGHG------V---DK----KSK------R- >GAMMA_Actinobacillus_pleuropneumoniae_L20 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAE-LHKG------------KP-YAPLLDSKSKTGGRNNLGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSVGDTIQAGV-S-AP-IKAGNALPMR NIPVGTTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECTATIGEVGNSEHMLRVLGKAGAN -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRVFT-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--SAIQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT---------EGEEF-----TL---GQ-EINV--D-I-FTDVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGA-VPGATNSDVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGITFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQE----------------R-LVVVEKF----EIE-A------ --PKTKLII--TANLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VVITADAV KQIEAKLHDYYRDQV----VNELKAKFNYSSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLNA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAAFNFPFMSRVA-K--APVNIPAGVEVK-L--- -N-G--Q-LLTVKGKNGELSREI--HN-A--VEVNQDA-NA--LTF----V-P--RTGANAD-AQAGTARALVNAMVIGV TEGFTKKLQLVGVGY--RAQMKG-NV--VALS--LGYSHPIEHTL-P-A-GVTGECP--S-QTEIVLKS-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYSDEVVRTKEAK----------------------------------------- -------------------------------------------------------------------------------- ------------------------MR-L--NSLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLNDLVTLESLKAA-NVITVK---------VIL--AGK-I-E-K-A-VVV- KGLGVTKGAKAAIEAAGGSI-K---VHK--GRN---RGIA--GGTEVSFG----------TFGLKAV--GRCRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEIARHAFALAAAKLPVKTTF-VKKVARIRRATRARHLM----REQGATRLVVHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKVI-KEQV----KYT-GNKDAAAVVGKLVAER--ALAKG-IQAVAFDRSGFKYH--GRVQVLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAQALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADVDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLTGK------DK-GKR GKVTQVLPNGK---VI--VEGVKIITKHEK----PV--PALGKA-GGLVKKEAAIDASNIA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EII--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTQ D--FADNLDGDFKVRKFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVSQIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIASVLAEEGYVESFK IVE--------G----SKPELEITLKYF---QNK-----------PVVESIQRVSRPGLRIYKRKDELPKVMGGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGKVVSDKMDKSFVVAIERTVKHPLYG KFIRRTTKLHVHDEN--NEAKLGDVVEIKECRPVSKTKSHTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Actinobacillus_pleuropneumoniae_sv_7,_AP76 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAE-LHKG------------KP-YAPLLDSKSKTGGRNNLGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSVGDTIQAGV-S-AP-IKAGNALPMR NIPVGTTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECTATIGEVGNSEHMLRVLGKAGAN -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRVFT-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--SAIQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRTE---------GEEF-----TL---GQ-EINV--D-I-FTDVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGA-VPGATNSDVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGITFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQE----------------R-LVVVEKF----EIE-A------ --PKTKLII--TANLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VVITADAV KQIEAKLHDYYRDQV----VNELKAKFNYSSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLNA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAAFNFPFMSRVA-K--APVNIPAGVEVK-L--- -N-G--Q-LLTVKGKNGELSREI--HN-A--VEVNQDA-NA--LTF----V-P--RTGANAD-AQAGTARALVNAMVIGV TEGFTKKLQLVGVGY--RAQMKG-NV--VALS--LGYSHPIEHTL-P-A-GVTGECP--S-QTEIVLKS-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYSDEVVRTKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NSLSPAEGA-KHSAKRLG-RGISSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLNDLVTLESLKAA-NVITVK---------VIL--AGK-I-E-K-A-VVV- KGLGVTKGAKAAIEAAGGSI-K---VHK--GRN---RGIA--GGTEVSFG----------TFGLKAV--GRCRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEIARHAFALAAAKLPVKTTF-VKKVARIRRATRARHLM----REQGATRLVVHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKVI-KEQV----KYT-GNKDAAAVVGKLVAER--ALAKG-IQAVAFDRSGFKYH--GRVQVLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAQALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADVDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLTGK------DK-GKR GKVTQVLPNGK---VI--VEGVKIITKHEK----PV--PALGKA-GGLVKKEAAIDASNIA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EII--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTQ D--FADNLDGDFKVRKFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVSQIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEISGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIASVLAEEGYVESFK IVE--------G----SKPELEITLKYF---QNK-----------PVVESIQRVSRPGLRIYKRKDELPKVMGGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGKVVSDKMDKSFVVAIERTVKHPLYG KFIRRTTKLHVHDEN--NEAKLGDVVEIKECRPVSKTKSHTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Actinobacillus_succinogenes_130Z Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLDTKSKTGGRNNLGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSVGDEIQAGV-N-AP-IKVGNSLPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECVATIGEVGNSEHMLRVLGKAGAN -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRVFT-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--TAVQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT---------EGEEF-----TL---GQ-EINV--D-I-FADVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGA-VPGATNSDVIVK--MELQVVG-AN-----NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGITFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVEKF----EID-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VVVTVDAV KQIEAKLHDYYRDQV----VNELKTKFNYASVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKNDEEGQALLAAFNFPFMSRVA-K--APVNIPAGVQVS-L--- -N-G--Q-LLTVKGKNSELSRTI--HN-S--VEVKEDN-GA--LTF----A-P--REGAGAD-AQAGTARALVNAMVIGV TEGFTKKLQLVGVGY--RAQVKG-NS--ISLN--LGFSHPVEHTL-P-A-GITAECP--S-QTEIVLKG-ADKQLIGQVA ADIRAYR------KPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKITVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGK-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLNDLVTLEALKAA-NVITAK---------VIL--AGE-I-N-N-A-VTI- RGLRVTQGAKAAIEAAGGSV-K---VHK--GRN---RGLA--AGTEVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEIARNAFALAAAKLPIKTTF-VKKSARIRRAARARHMM----REQGVTRLVVHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKEI-SAQV----KYT-GNKDAAAVVGKLVAER--ALAKG-VKDVAFDRSGFKYH--GRVQSLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAAALEILTYT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLAGK------DK-GKR GKVTQVLPNGK---VI--VEGVKIITKHEK----PV--PALGKE-GGLVKKEAPIDASNVA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EII--MGQKVHPHGIRLG--IV-KPWSSTWFA------NTQ D--FADNLDGDFKVRKFL--NKELM-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRTAVAKIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIANVLAAEGYIESVK VLE--------G----AKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGRVISDKMDKSFTIAIERKVKHPLLG KFIRRTTKLHVHDEN--NEARLGDWVEIKECRPVSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Aeromonas_hydrophila_hydrophila_ATCC_7966 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKIVNQD-LYKG------------KP-FAALLDKKDKSGGRNNNGRITTRH-IGGGHKQH---- YRIVDFK-R--DK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAPKGLKAGDAIASGA-D-AA-IKVGNTLPMR NIPVGSTVHAVEMKPGKGAQLARSAGTFIQILAR--EGNYVTLRLRSGEVRKVLAECRATIGEVGNSEHMLRQLGKAGAN -RWR-----GIR-P-TVRGMAMNPVDHPHGGGEGRN----KGMQ-PVSP---WGQKAKGFKTR-KNKR-TD-K-YIVRRR --------------------------------MTI---G-LVGRKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----SVE----T--DGY--NAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------NNGETF-----TV---GS-ELKV--D-L-LADVKLVDVTGTSKGKGFAGTVKRW NFRT-QDMTHGNSLSHRV-PGSIGQN-QTPG-RVFKGKKMAGHMGAERVTTQNLELVRVDAERN---------------- ----------LLLIKGA-VPGATNGNVIVK--MELVMKD-AK-----SALEVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQLTRSE--------VS-GGGKKPW---------RQKGTGRAR--------AGS---IR-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIRSILSELVRQE----------------R-LIVVEKF----GIE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VLMTADAV KQIEAKLHDYYKSDV----VNELSKQFGYKTIMQVPRIEKITLNMGVG-EAISDKKLLENAAADMAAISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLICISVPRIRDFRGLNA-KAFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTS-----------------------ANTDEEGRALLAAFNFPFMSRVA-K--APVTIPAGVEVT-L--- -N-G--Q-ELSIKGGKGSLVRSI--HA-G--VEVTKED-NV--LKF----A-P--RDGAGAD-AQAGTARALVNNMVIGV TQGFERKLQLVGVGY--KASIKG-NA--VALA--LGFSHPVEHAL-P-A-GVTAECP--T-ATEIVLRG-VDKQLVGQVA ADIRAYR------APEPY---KGKGVRYANEQVRTKEAK----------MIQMQSMLGVADNSGARSVMCIKVLG-SHRR Y--AGIGDIIKVSIKEAIPR-G-------KVKKGDVYNAVVVRTRKGVRRPDGSVIRFDNNAAVLLN-NNQQ-PIGTRIF GPVTRELR-NEKFMKIVSLAPEVLMR-L--NTLSPAAGS-KRVKHRPG-RGIGSGL-GKTGGRGVKGQTSRSGGGKV--- -RNGF-E-GGQMPLKIRLPK-FG--FFSVRLNEIVDVSTLKQA-GVITAK---------VVL--SGN-I-D-R-A-VTV- RGLSVTKGARAAIEAAGGKI-K---THK--GRN---RGLA-NSGNEVSFG----------TFGLKAT--SRGQLTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVCPIQP-GKVLYEM--DG-- VPEALAREAFALAAAKLSVQTTF-VKKAARLRRATRARKKM----QELGATRLVVHRTPRHIYAQVIAA---N--GSEVL ASASTV-EKAI-SEAI----KYT-GNADAATAVGKAIAER--AIAKG-VQNVSFDRSGFKYH--GRIAALAAAARDAGLQ F--------------------------------------------------------------ME-AIAKHRYARTSAQK ARLVADQVRGLSVDKALNILTFS---------------------------------PKKAAALVKKVLESAIAN----A- EHNE-GADIDALRVATIMVDEGPSMKRIRPRAKGRADRILKRTAHITVVVSDAAKIRREDEVIVLTGK------DK-GKR GKVTQVLIAKG--KVI--VEGINQVKKHQK----PV--PALGQA-GGIVTKEAPIDVSNVA-LFNSAT-------GK--A --DRVGFRI----E--------DGKVR---FFKSTG---ELV--MGQKVHPNGIRLG--IT-KPWNSTWFA------NTK D--FADNLYSDFQVRQFL--TKELK-----NASLSKITIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRKAVAAIAQ INISEVRK---PELDGKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAASKVAVSM-PSSKLKVAIAKVLKEEGYITGYS VAG----D--------VKPELEIELKYF----QG-------K---PVVELIQRVSRPGLRIYKRTTDLPKVMGGLGVAIV STSKGVMTDRAARKASMGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTDKTVDALMRLDLAAGVDVQISLIRTLQGRVISDKMDKSITVAIERKVKHPIYG KIIKRTTKLHVHDEN--NECKAGDLVEIRECRPLSKTKSWTLVAVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PVKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Aeromonas_salmonicida_salmonicida_A449 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKIVNQE-LYKG------------KP-FAALLDSKSKSGGRNNNGRITTRH-IGGGHKQH---- YRIVDFK-R--DK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAPKGLKAGDAIASGA-D-AA-IKVGNTLPMR NIPVGSTVHAVEMKPGKGAQLARSAGTFIQILAR--EGNYVTLRLRSGEVRKVLAECRATIGEVGNSEHMLRQLGKAGAN -RWR-----GIR-P-TVRGMAMNPVDHPHGGGEGRN----KGMQ-PVSP---WGQKAKGFKTR-KNKR-TD-K-YIVRRR --------------------------------MTI---G-LVGRKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----SVE----T--DGY--NAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------NNGETF-----TV---GS-ELKV--D-L-LADVKMVDVTGTSKGKGFAGTVKRH NFRT-QDMTHGNSLSHRA-PGSIGQN-QTPG-RVFKGKKMAGHMGAERVTTQNLELVRVDAERN---------------- ----------LLLIKGA-VPGATNGNVIVK--MELVMKD-AK-----SALEVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQLTRSE--------VS-GGGKKPW---------RQKGTGRAR--------AGS---IR-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIRSILSELVRQE----------------R-LIVVEKF----GIE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VLMTAEAV KQIEAKLHDYYKSDV----VNELAKQFGYKTIMQVPRIEKITLNMGVG-EAISDKKLLENAAADMAAISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLICISVPRIRDFRGLNA-KAFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTS-----------------------ANTDEEGRALLAAFNFPFMSRVA-K--APVTIPAGVEVT-L--- -N-G--Q-ELSIKGGKGSLVRSI--HA-G--VEVTKED-NV--LKF----A-P--RDGAGAD-AQAGTARALANNMVIGV TQGFERKLQLVGVGY--KASIKG-NA--VALA--LGFSHPVEHAL-P-A-GVTAECP--T-ATEIVLRG-VDKQLVGQVA ADIRSYR------APEPY---KGKGVRYANEQVRTKEAK----------MIQMQSMLGVADNSGARSVMCIKVLG-SHRR Y--AGIGDIIKVSIKEAIPR-G-------KVKKGDVYNAVVVRTRKGVRRPDGSVIRFDNNAAVLLN-NNQQ-PIGTRIF GPVTRELR-NEKFMKIVSLAPEVLMR-L--NTLSPAAGS-KPEKQRRG-RGIGSGL-GKTGGRGVKGQTSRSGGGKV--- -RAGF-E-GGQMPLKIRLPK-FG--FFSVRLNEIVDLSTLKQA-GVVTAK---------VVL--SGN-I-D-R-A-VTV- RGVSVTKGARAAIEAAGGKI-K---THK--GRN---RGLA-NTGNEVSFG----------TFGLKAT--SRGQLTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVCPIQP-GKVLYEM--DG-- VPEALAREAFALAAAKLSVQTTF-VKKAARLRRATRARKKM----QELGATRLVVHRTPRHIYAQVIAA---N--GSEVL ASASTV-EKAI-SEAL----KYS-GNADAATAVGKAIAER--AIAKG-VQNVSFDRSGFKYH--GRVAALATAARDAGLQ F--------------------------------------------------------------ME-AIAKHRYARTSAQK ARLVADQVRGLSVDKALNILTFS---------------------------------PKKAAVLVKKVLESAIAN----A- EHNE-GADIDALRVATIMVDEGPSMKRIRPRAKGRADRILKRTAHITVVVSDAAKIRREDEVIVLTGK------DK-GKR GKVTQVLVTEG--KVL--VEGINLVKKHQK----PV--PALGQA-GGIISKEAPMDVSNVA-LFNSAA-------GK--A --DRVGFRI----E--------DGKVR---FFKSTG---ELV--MGQKVHPNGIRLG--IT-KPWNSTWFA------NTK D--FADNLYSDFQVRQFL--TKELK-----NASLSKITIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRKAVAVIAQ INISEVRK---PELDGKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAASKVAVSM-PSSKLKVAIAKVLKEEGYIAGYS VAG----D--------VKPELEIELKYF----QG-------K---PVVELIQRVSRPGLRIYKRTTDLPKVMGGLGVAIV STSKGVMTDRAARKASMGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTDKTVDALMRLDLAAGVDVQISLIRTLQGRVISDKMEKSITVAIERKVKHPIYG KIIKRTTKLHVHDEN--NECKAGDLVEIRECRPLSKTKSWTLVAILEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PVKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTLSRPC------C-------------------- >GAMMA_Alcanivorax_borkumensis_SK2 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNED-LHKG------------AP-YAPLLEAKAKNGGRNNNGRITTRH-KGGGHKQK---- YRVIDFR-R--NK-DGIAGVVERLEYDPNRTAHIALVKYL-DGERRYILAPKGLKAEDRIQSGE-D-AP-IKLGNALPLR NIPLGSTIHNVEMKPGKGGQIARSAGTSVQLLAK--DGQYVTLRLRSGEMRKVHADCKATIGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEGRS----SGGRHPVTP---WGVPTKGYKTR-TNKRTTK---MIVRDR --------------------------------MAI---G-VIGRKCGMTRVFT-EEGV---------SVPVTVIEVGPNR VSQVK----TEE----S--DGY--QAVQVTV-------GE--RVTK----------AQAGHFK----------------- ---AG-VEAGRGVWEFRA---------EAGEF-----EA---GS-SVTV--E-G-FEAGQMIDVTGTSKGKGFAGGVKRW NFST-QDATHGNSLSHRA-PGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQNLEVVRVDADKN---------------- ----------LLLVKGA-VPGATGGDVIVR--MNLNT---ASG----GTVTVSEVAF----GK-DF-NEPLVHQVVTAFL AGARQGSKAQKNRSD--------VS-GGGRKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGKTFAAV-P-RDHSQKVNRKMYRGALQCIMSELVRQE----------------R-LVVVDEF----TVD-S------ --PKTKLIV--TDNVD--E---NLFMASRNLPKVD-V---------------RDSQGVDPVSLIAFEK----VLITVPAL KKLESDLKKIYQDEI----APKLKEELGLGNIMEVPKITKITLNMGVG-EASADRKAMEGALSDMTAISGQKPLVTNARK SVAGFKIREGWPIGCKVTMRNQRMYEFLERLVSVAIPRIRDFRGLNP-KSFDGRGNFSMGLREQIVFPEID-----FDKV DKLRGMDITITTT-----------------------AKTDDEARALLRAFNFPLMSRVA-K--SPVNLPKGVEVK-I--- -D-G--Q-KVAVKGGKGSLEHEV--HE-L--VAVSLED-GV--VSV----K-P--HDDQKGW-ALAGTTRALLNNMVTGV ADGFERKLQLLGVGY--RAQAQG-KV--LNLT--LGFSHPVAYQL-P-E-GITVETP--S-QTEIVIKG-IDKQLVGQVA ANVRAFR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQTESMLEVADNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------RVKKGDVMTAVVVRTRKGVRRPDGSLIRFDENAAVLLN-NNKA-PVGTRIF GPVTRELR-TEQFMKIISLAPEVLMR-L--NDLHPAEGS-RPEGKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGS-V--- -KPGF-E-GGQMPLQRRVPK-FG--FTSVRLAELIDLASLKAA-NIVRAK---------IVL--QGE-I-D-R-A-VTV- RGVALTKGAREAVEKAGGKV-K---VMK--GRN---RGLA-QRGSKVSFG----------TIGLQAT--GRGRITARQIE AARRAMTRHI------KRGGKIWIRVFPDKPITNKPLEVRMGKGK---------GSVEYWVAQIQP-GKMLYEM--EG-- VSEDVAREAFRLAAAKLPVSTRV-VKKVARLRRAKRTRLKI----RELGEVRLCVHRTPRHIYAQVISA---A--GDQVL ASASTV-EKDL-RA------DAT-GNADAATKVGQIIAQR--AKEAG-IERVAFDRSGFKYH--GRVKALADAARENGLE F-------------------------------------------------------------ATE-VAARLRGARISAQK ARLVADQVRGLEVEKALNLLEFS---------------------------------PKKAAKIVKKVLESAIAN----A- ENND-GADVDELKVSTVFVDEGMTMKRIRPRAKGRADRILKRTCHITVKVSEMLKIKRDDEIIVIAGK------DK-GKR GSVQQVLDN-G--RLI--VAGVNMVKKHVK----AN--PNRGTQ-GGIVEQEASLNASNVA-IWNPKT-------QK--A --DRVGFRF----E--------DGKVR---FFKSNG---EAL--MGQKVHPVGIRLG--IV-KEHNSLWYA------GPK S--YSDCLVTDLQVREYL--FKRLK-----SASVSRIKIERPS-E-NVRITIATARPGIVIGKKGEDVERLRRDVAAKVH INIEEVRK---PDLDARLVGDNVAGQLERRVMFRRAMKRAVQNAMKS-GAEGIRIQLSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYASVRAETTYGTIGVKVWIFMSMQDTLADMFTRIRNAQMAKKVQVEI-PASKAKEAVAKVLKDEGYIAGYE VTG----D--------KKPVMTVELKYY----EG-------S---PVIEKIARVSRPGLRVYKSAGEIPKVKDGLGVMIV STNQGIISDRAARKANIGGELICEVSMANQRIRIRLKAFDHRLIDQSAQEIVDTAKRTGAQVTGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRLVDIVEPTDKTVDALMKLDLAAGVDVQISLRRTATGKVISNKGDKTITVLVERRVQHPIYG KIIKRSTKLMAHDEE--NQCREGDLVTIEECRPLSKRKAWMLVNVVEQS------------------------------- -MPRSL-KKGPFVDH-HLLGKVEDAVE---AGSRK----PIKTWSRRSMIIPEMVGLTIAVYNGKQHVPVMVSE-HMVGH KLGEFALTRNYRGHA------V---DK----KAK------R- >GAMMA_Aliivibrio_salmonicida_LFI1238 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKIVNAD-LHKG------------KP-YAPLLEKNSKSGGRNNNGRITVRH-VGGGHKQH---- YRLIDFK-R--TK-DGIPAIVERLEYDPNRSANIALVLFA-DGERRYIIAPKGLKAGDTVQSGV-D-AP-IKAGNCLPLR NIPVGSTVHCVELKPGKGAQVARSAGAYAQIIAR--DGAYVTLRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAT -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGMPTKGFKTR-KNKS-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRIFT-EEGV---------SIPVTVVEVEVNR VSQVK----TVE----T--DGY--NAIQVTC-------GS--KVSK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----TV---GA-ELSV--E-I-FNEIKKVDVTGTSKGKGFQGAIKRW NFAT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERCTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGSTGGNVIVK--MELMVKG-A------AALTVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RSGGVTFAAK-P-QDHSLKVNKKMYRGALKSILSELVRQD----------------R-LIVVEDF----SIE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-A---------------RDVAGIDPVSLVAFNK----VLMTAAAV KQVEAKLHDYYKSSV----VAELTKEFSYSSVMQVPRVEKITLNMGVG-EAINDKKLLENAAADMAIISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVSIALPRVRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTS-----------------------ANTDAEGRALLAAFNFPFMSRVA-K--APVVLPAGVEVK-L--- -N-G--Q-EITIKGGKGELTRVL--NN-A--VVVSQED-NS--IVF----G-P--REGANAW-AQAGTARALVNNMVVGV NEGFTKKLTLKGVGY--RATMKG-NA--VGLT--LGFSHPVEHAL-P-E-GIKAECP--T-QTEIIITG-CDKQVVGQVA ADIRSYR------KPEPY---KGKGVRYADEIVRTKEAK----------MIQMQSTLDAADNSGARKVMCIKVLG-SHRR Y--AHIGDVIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSIIRFDRNACVLLN-DTTEQPVGTRIF GPVTRELR-NAKFMKIVSLAPEVLMR-L--NTLSPAAGS-NPSKKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RVGF-E-GGQMPLKQRLPK-FG--FTSVRLSELIDLNSLKAA-NVITAK---------VVL--SGE-I-A-T-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VMT--GRN---RGLA--KGTEVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHV------KRQGQIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEM--NG-- VPEELAREAFRLAARKLPIKTTF-VKKASRIRRATRARRKI----AELCATRLVVHRTPRHTYAQVIAP---N--GSEVI AAASTV-EKAI-REQV----GNT-SNKAAAVAIGKLIAER--AIEKG-ITNVAFDRSGFQYH--GRVAALADSAREAGLK F--------------------------------------------------------------ME-AIAKHRFASISPQK ARLVADQIRGKSVDQALEILTFS---------------------------------NKKAAVIIKKVVESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPIMKRIMPRAKGRADRILKRSSHITIVVADAAKIRRNDEVIVLVGK------DK-GKK GKVTKVLET-G--KVI--VEGINLVKKHQK----PV--PALGQQ-GGIVEKEAAIDASNIA-IFNDAT-------GK--A --DRIGFRF----E--------EGKVR---FFKSNG---ETI--MGQKVHPNGIRLG--IV-KPWNATWFA------SSQ E--FADNLDGDFKVRQYL--TKELK-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAGVAKIAQ INIAEVRK---PELDAHLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAQGIKVQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATASAHTQYGVIGVKVWIFMSMQDPISDMLTRVRNGQSANKVAVKM-PSSKLKVAIAALLKAEGYIADFA VEG----D---I-----KPELEITLKYF----QA-------K---QVIEQIQRVSRPGLRVYKKNDALPSVMGGLGIAVI STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLTS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLIRTMQGRVISDKMDKSIVVAIERMVKHPIYG KYIKRTTKLHAHDEN--NECGQGDLVVIRECRPLSKTKSWTLVNIVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPTMINLTIAVHNGRQHVPVFVTE-DMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Alkalilimnicola_ehrlichei_MLHE-1 Concatenation of 2 sequences MALVKAKPTSPGRRFVVTVRNKE-LHAG------------AP-YEPLVEKKTRKGGRNNTGRITTRH-RGGGHKQR---- YRVIDFR-R--DK-DGVPGQVERLEYDPNRSANIALVLYR-DGERRYIIAPRGVSAGTEIVSGV-D-AP-IKPGNALPLR NIPVGTQVHCVELRPGKGAQLARSAGANAQLVAR--EGRYATVRLRSGEMRQVLAECKATVGEVGNSEHALRSLGKAGAK -RHK-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGHKTR-SNKR-TD-K-FIVRRR --------------------------------MSI---G-IVGRKAGMTRVFT-EDGA---------SVPVTVIEASPNR VTQVR----TPE----R--DGY--SGVQVTA-------GS--RVSK----------PMAGHFA----------------- ---AG-VDAGRGVWEFRV------SDGQAIEL-----EA---GK-ELTV--E-T-FEAGQVVDITGTSKGKGFAGTVKRH NFRT-QDATHGNSLAHRA-PGSIGQN-QTPG-RVFKGKKMAGQMGNKRSTVKNLEVVRVDAERH---------------- ----------LLLVRGS-VPGAVGSDVIVR--MELQLRN-AQGQTD-GSVQVADAAF----GD-RF-REALIHQVVVAYL AGARAGTRAQKTRAE--------VR-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- VGGGRAFAAR-P-QDHGQKVNKKMYRGALRSIFSELARQE----------------R-LVVVESI----GVD-E------ --PKTALIV--ADEVD--Q---NLYLAARNLPGVD-V---------------RDVPGLDPVALVGAEQ----VVITVQAL RQVEVRLQEQYQAEV----KQALRDRFGYDNVMEIPRLSKVTLNMGLG-EAVRDKKVLESAQAEMAEIAGQKPILTYARK SVAGFKIRDGWPIGCKVTLRRERMYEFLDRFINVAAPRIRDFRGFNP-RSFDGRGNYNLGVREQLIFPEID-----YEKV DAVRGMDITITTT-----------------------AKTDEEGQALLEGFNFPFMSRVA-K--RPVKVPSGVEVK-L--- -D-G--Q-DVKVKGPKGELAWTV--HD-W--VAVEQAD-GE--LRV----Q-A-QLDDRRAV-ALAGTTRALLNNMVTGV SQGFERKLELRGVGY--RAQVQG-KN--LNLT--LGFSHPVDYPV-P-E-GITIEAP--S-QTEIVVKG-ADKQQVGEVA AQIRAFR------PPEPY---KGKGVRYADERVVLKEAK----------MIQMQTTLGVADNSGARQVQCIKVLG-SRRR Y--AGIGDIIKVSVKDAIPR-G-------RVKKGEVYNAVVVRTRRGVRRPDGSVIRFDGNAAVLLN-NQLQ-PIGTRVF GPVTRELR-SEKFMRIISLAPEVLMR-L--NSLRPAAGS-RPDANRVG-RGAGTGN-GKTAGRGHKGQHSRSGGF-T--- -KVGF-E-GGQMPLQRRVPK-VG--FRSVRLSELVDLLTLKQA-GIINAK---------VIA--SGK-V-E-R-A-VTV- QGLAVTKGAREAIEAAGGKV-K---QQK--GRN---YGLA-SRGNAVSFG----------EYGLKAV--TRGPITARQIE AGRRAINRHV------KRGGKVWIRVFPDKPITAKPLEVRQGKGK---------GNVDHWAFPVQP-GRVLYEI--EG-- VSEELAREAFRRAAAKLPVRTTF-VKKATRLRRARRARAKI----AELKVHRLSVHRTPRHMYAQIIAP---D--GGRTL VAASTV-EKDL-RSRA----EGT-GNCSAAAEVGRLIAER--AKAAG-VERVAFDRSGFKYH--GRVKTLADAAREAGLQ F--------------------------------------------------------------ME-TSAKLKFSRLSPQK ARLVADQVRGLPVEKALEILEFS---------------------------------PKKAAAIVRKVLDSAVAN----A- EHND-GADIDALRVARIFVDEGPMLKRIRPRAKGRANRILKRTSHITVTVAEMRKIRQGDDVVIIAGK------DK-GRR GRVIRVYPDQE--KLL--VENVNVVKRHRK----GN--PQQGEA-GGIIEQEKPIHQSNVA-LYNPAT-------EK--G --DRVGIRV---LE--------DGKAR---YFKSNN---ELV--MGHKVHPTGFRLG--VT-EDWRSMWYA------GSS N--FGEYLNTDLQVRNFI--RKKLA-----HASVSRIRIERPA-K-NALVTIHTARPGIVIGKKGEDIDRLRGEVARLVH INIEEIRK---PELDAKLVAESVAQQLERRIMFRRAMKRAVGNAMRL-GAQGIKVHVSGRLNGAEIARSEWYREGRVPL- -HTLRANIDYGVAEAHTTYGVIGVKVWVFMSMTDPIADMLTRVRNAQRAEKAEVSM-PSSKIKQAIANVLKEEGYIESFE VGG----D---E----KKPELKISLRYY----QG-------E---PVIRELERASSPGLRLFKDKGSLPRVRNGLGVAIV STSKGVMTDRAAREAGHGGEVLCYVFMANQRIRIRLKAFDHRLIDQSAREIVETAKRTGAHVKGPIPLPVKKEKFTILIS PHVNKDAR-DQYEIRTHKRLMDIIDPTDKTVDALMKLDLAAGVDVQIKLTRNVQGRVVSNKADKTITVLVERRVRHPLYG KYIRRSSKMQAHDEG--NECQVGDVVTIEQCRPISKSKAWRLVKVLERA------------------------------- -MPRSV-KKGPFVDG-HLLSKVEKARE---SNSKR----PIKTWSRRSMVLPQMVGLTIAIHNGRQHVPVLINE-NMVGH KLGEFAATRTYRGHA------A---GK----KTK-------- >GAMMA_Alteromonas_macleodii_Deep_ecotype,_DSM_17117 Concatenation of 2 sequences MPLLKAKPTSAGRRHVVQVVNPD-LHKG------------AP-YAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQH---- YRVIDFK-R--NK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYILAPKGMKAGDAIQSGS-G-AP-IKSGNTLPMR NIPVGTVVHAIEMKPGKGAQIARSAGAYAQILAR--DGNYVTLRLRSGEMRKVLSDCRATIGEVGNAEHMLRSLGKAGAT -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGKKTR-SNKR-TD-K-LIVRRR --------------------------------MAI---G-LVGRKVGMTRIFT-EDGT---------SIPVTVIEATPNR VTQLR----TEE----S--DGY--RALQVTA-------GT--KINK----------AEAGHFK----------------- ---AG-VEAGRTLVEFRL------EENEGADI-----EV---GS-EITV--E-I-FNDTKKIDVTGTSKGKGFQGAIKRW NFSS-QRMTHGNSLSHRA-PGSIGQN-QSPG-KVFKGKKMAGQLGNKQVTTQSLEVVRVDVENG---------------- ----------LILVKGA-VPGATGNDVIVK--MELTLKD-AQ-----SALEVSEATF----GR-EF-NEALVHQVVVAYG AGARQGTKAQKTRAE--------VR-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- VGGGRAFAAK-P-RDFDQKVNKKMYRGAIKSILSELIRQD----------------R-LVVVEKF----GVD-A------ --PKTKLIV--TPEVD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFEK----VLMTADAV KQLEAKLHDFYKETV----VAELAKQFGYKSVMQVPRIEKITLNMGLG-EAVADKKVLENAQADMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLISIAIPRVRDFRGLNP-KSFDGRGNYSMGVREQIIFPEID-----FDKV DKVRGMDITITTS-----------------------ANTNDEARALLDAFNFPFMSRIA-K--APVDVVSGVEVS-I--- -S-G--Q-EVTVKGSKGTLTRVF--ND-A--VEVAQEE-NQ--LKA----L-P--REGADSW-AQAGTVRSILNAMVQGV SQGFEKKLTLLGVGY--RAQAQG-SK--LNLT--LGFSHPVVYEM-P-E-GITVETP--S-QTEIVVKG-ADKQVVGQVA ANIRGYR------PPEPY---KGKGVRYADENVRRKEAK----------MIQMQTNLDVADNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGDVLNAVVVRTRKGVRRADGSTIRFDGNAAVMLN-ANKQ-PIGTRIF GPVTRELR-SENFMKIISLAPEVLMR-L--NTISPAEGS-KPTGKRSG-RGIGSGL-GKTGGVGHKGQKSRSGGR-V--- -KPGF-E-GGQMPIQRRLPK-FG--FTSVTLAEIASLETLKAA-GLVKVK---------VVK--SGE-V-S-R-A-VTV- SGLKVTKGAKEAIEAAGGKV-K---MHK--GRN---RGFA--AGSTVAFG----------TYGLKAV--GRGRMTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVCQIQP-GRVLYEM--EG-- VPENLAREAFELAAAKLPFKTTF-VKKTARIRRATRARAKI----RELAAHRLVVNRTPRHIYAQLIAP---C--GSEVL AAASTV-EKDL-AKDL----KST-GNAEAATVVGKAIAER--ALEKG-IKTVAFDRSGFQYH--GRVKALADAAREAGLQ F--------------------------------------------------------------ME-ALAKHRFARTSAQK ARLVADQIRGLHVEKALEVLAYS---------------------------------PKKSAALVKKVLESAIAN----A- EHNE-GADIDELVVAKVFVDEGPTMKRIKPRAKGRADRIFKRSSHITVVVADANKIRRDDEVVVLAGK------DK-GKQ GKVLRVLIADN--RVI--VEGVNLVKKHTK----PN--PQLGVA-GGIVEKEASIHVSNVA-IVNPAT-------GK--A --DRVGFRF---ED--------EKKVR---FFKSNG---ELV--MGQKVHPTGIRLG--IS-KPWTSTWYA--------- --------------------------------------------N-TA-------------------------DY----- -----------------------ADKLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTFRADIDYATSEASTTYGIIGVKVWIFMSMQDPIADMFTRIRNGQMAQKVSVTM-PSSKLRVAICEVLKAEGYITDFA ASG----D--------VKPVLEVTLKYF----EG-------K---QVIDTIERVSRPGLRIYKKKDELPKVMGGLGVAIV STSKGVMTDRAARNAGMGGEIIGYVAMPNQRIRIRLKAFDHKLIDQSTAEIVETAKRTGAQVSGPIPLPTRKERYTVLIS PHVNKDAR-DQYEIRTHKRLVDIIEPTDKTVDALMRLDLAAGVDVQISLIRTVQGRVVSNKMDKTITVVVERFVKHPIYG KFIKRSTKLHAHDEN--NVCNQGDVVTVRECRPLSKNKSWMLVDVVEKA------------------------------- ------------------------------------------------MIIPDMIGLTIAVHNGRQHVPVIISD-EMVGH KLGEFAPTRTYRGHV------A---DK----KAK------R- >GAMMA_Azotobacter_vinelandii_DJ,_ATCC_BAA-1303 Concatenation of 2 sequences MAIVKCKPTSAGRRFVVKVVNQE-LHKG------------AP-YAPLLEKKSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-R--NK-DGIPATVERIEYDPNRTAHIALLKYA-DGERRYIIAPKGVVAGDQLISGV-N-AP-IKAGNTLPLR NIPVGSTIHGVELKPGKGAQIARSAGASAQLVAR--EGAYVTLRLRSGEMRKVLADCRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGFPTKGAKTR-SNKRTDN---MIVRRR -----------------------------------------------MTRIFT-EEGV---------SVPVTVIEIEPNR VTQFK----NAE----S--DGY--LAVQVTV-------GE--RVTK----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------EEGEY-----QS---GD-QITV--E-I-FQAGQLVDVTGQSKGKGYAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHLGAERVTVQSLEVVRVDSERN---------------- ----------LLLVKGA-IPGATGGDVIVR--MQLNVNG-AQ------AIEVSERTF----GG-EF-NETLVHQAVVAYL AGGRQGSKQQKNRSD--------VS-GGGKRPW---------RQKGTGRAR--------AGT---SR-GP----LW---- RGGGVTFAAR-P-QNHDQKLNKKMYRAALRSILSELVRQE----------------R-LVVVEDF----AVD-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVLGSDPVSLIAYDK----VLITVPAV KKFEARLKEIYRNEI----APKLKNELQLVNVMEVPRITKITLNMGLG-EAVGDKKVIENAVADLEKITGQKPVVTYARK SIAGFKIREGWPIGVKVTLRRDRMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARTDDEGRALLRAFNFPF-------------------------- -----------MKGAKGSLELNV--HP-S--VEVVQEA-GE--LRF----A-A--RNGQQNR-AMAGTTRALVNNMVIGV SQGFERKLQLVGVGY--KAQAKG-QV--LSLA--LGFSHPVDYQL-P-Q-GITAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------RPEPY---KGKGVRYSDEVVHRKEAK----------------MLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRPDGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLMQ-L--NDLRSAPGA-RREKLRPG-RGIGSGL-GKTGGRGHKGQTSRSGGK-I--- -APGF-E-GGQQPLHRRLPK-FG--FTSIRTSELVTLQALKDA-NLVNVK---------VML--SGD-V-G-R-A-VTL- KGIAVTKGARAAIEAAGGKI-K---QMT--GHN---RGLA-HRGSKVSFG----------EFALKSV--SRGRLTARQIE AARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GNVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATTF-VKKETRLRRARKTRLKM----RELEVVRLCVHRSSQHIYAQVITA---D--GGKVL ASASTL-DKEL-RG------AAT-GNVEAAKKVGLLVAER--AKAAG-VTQVAFDRSGFKYH--GRVKALADAAREGGLE F------------------------------------------------------------------------------- --MVADQIRGKKVGDALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VSGVNLIKRHSK----PN--PMLGVQ-GGIVEKEAPLHVSNVA-IFNAET-------SK--A --DRVGFKI----E--------DGKIR---IFKSTQ---KPV--MGQKVHPVGIRLG--IV-KEHTSVWYA------DRK N--YADYLYADLKVREYL--QDKLK-----SASVSRIDIARPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDSMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWIF--------------------------M-PSSKLKVAVANVLKNEGYISDYQ VSS----D--------AKPLLSIELKYF----EG-------R---PVIEELKRVSRPGLRQYKSVDQLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDET--NQCRIGDTVTIRETRPLAKTKSWMLVEVVERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEVAVE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLISE-DMVGH KLGEFAATRTYRGHA------A---DK----KAK------R- >GAMMA_Candidatus_Ruthia_magnifica_Cm Concatenation of 2 sequences AQVIKRKPTSPGRRFVVSIVDKE-LHKG------------AS-YAPLTQSKNRISGRNNVGRITTRH-KGGGHKRR---- YRIIDFK-RN--K-DDITARVERLEYDPNRSANIALVLYT-DGERRYIIAPHGLSVGYTIVSGN-S-VA-IQAGNVMPLS NIPLGGVVHCIELKPMKGAQIARSAGAFAQLIAK--EGNYVTLRLRSGEVRKVLADCRATIGEVSRSEHSLKKLGKAGAT -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGKT-S--GGR-HPVSP---WGTPTKGYKTR-SNKR-TD-K-LILRHR --------------------------------MAM---G-LVGQKIGMTRLIS-DDGS---------ITPVSVIKIELNR IVQTK----TVD----T--NGY--SAIQVTT-------GV--KVPA----------AIKGHYK----------------- ---TS-QEIGLGLWEFRV---------EADEI-----TD---AT-SVDI--S-L-FSAGHYVNVVGRSKGKGFQGGVKRH NFQM-QDATHGNSISHRA-IGSTGQC-QEPG-RVFKGKKMAGHMGNEQVTQECLKIVKVDSERN---------------- ----------IIFVKGS-IPGATKGFVKIS--MKFKVLN-ISTNKS-STIEVADTVF----AR-GF-NQALVHQVTTAYM SGGRQGSKAQKNRST--------VS-GGSKRPW---------AQKGTGRAR--------AGT---TR-GP----IW---- RSGGVTFSAA-P-RGYAQKVNKKMYKGAISVIFSELARSE----------------R-LKVVSEF----NIK-E------ --IKTKLLM--TDELD--E---NLYLSSRNLYHVG-V---------------CDIQSIDPVSLIGYDN----VVVTEIAL KKIESRLQEQYKNEI----LPALQKELDMSNPMQVPKIEKITINMGLG-SALGDKKVLQSALKEMSLISGQKPLICNARK SVASFKLREGNPIGCKVTLRKERMYEFLDRLINIAIPRIRDFRGFKA-TAFDGRGNYNMGITEQITFAEID-----FEKV TRILGMDIAITTT-----------------------AKSDEEAKKLLVMFKFPFMSRVA-K--SPITIPTGVEVT-I--- -T-S--N-LMSVKGRFGQLNMSI--HP-C--IVITNTN-NK--LSFDITIT-E--KKEKKAW-AQAGTARANTANLIQGV TEGWEKKLTLIGVGY--RAKVME-RV--LNLT--LGFSHPINYKL-P-E-GITVEAP--S-QTEIIIKG-MDKQKVGQVA AEIRAYH------PPEPY---KGKGVCYIDEQVVRKEAK----------MIQMQTKLKVADNSGGVKAMCIKVLG-SKRR Y--ANIGDVIKVSIKEAASR-G-------KVKKGDVYDAVVVRTAHGVRRSDGSCIRFDNNAIVLLN-TKLE-PIGTRIF GPVTRELR-SAQFMKIVSLAPEVLMQ-L--NTLSPIQGE-KQSRKRVG-RGIGSGF-GKTCGRGHKGQKARSGGF-R--- -KVGF-E-GGQMPLQRRLPK-VG--FSSVTLSEIITIDALKAH-NLITVK---------VIL--SGE-I-I-K-T-VTL- TGIKTTKGAKLAIEAVKGLV-K---MMK--GRN---RGLA--TGYKVSFG----------EIGLQAV--SRCRMTARQIE SARRAMTRHV------KRQGKIWIRVFPDKPITKKPLEVRMGKGK---------GSVEYWVAQIKP-GQMLFEM--QG-- VDEIIIREAFALAAAKLPVKTTI-IKKQARLRRATKFRAKH----AQGSTKRLCVHKTAQHIYAQIISP---C--GTKVL ASASTL-TAKL---------KNG-GNVDAATKVGKEIAKA--ATSVK-VIKVAFDRSGFKYH--GRVKALADAAREGGLD F-------------------------------------------------------------MKE-VKAIHKYAKTSAFK VRLVANQIRLKSVDEALNILSFS---------------------------------NKKAAVLIKKVLNSAISN----A- EHND-GLDIDELFVASICIDEGSTMKRIRPRAKGKANRILKRTSHITVGVSKMKKIKLNDEVIIITGK------NK-DST GAVIKVLDS----KVL--VEGLNLAKKHVR----SN-PNA-GVT-GGITEIEVPLAVSNVA-IYNSAT-------KK--A --DRVGIRT---NK--------DGKER---FFKSNN---EVI--MGQKVNPKGIRLG--IV-KDWDSKWYA------NSQ D--YSKYLLSDIKVRDYL--FDKLT-----NASVSRIQIERLA-N-NAKITIHTARPGIIIGKKGADIEQLKSIVSKMVH INIEEIKK---PELDARLVAENIAQQLEKRVMYRRAVKRVLGNTTRL-GAKGIKVMVNGRLNGAEIARSEWYREGRVPL- -HTFRADVDYSSYGANTQYGVIGIKVWIFMSMSDPIADMLTRIRNAQMVEKKEVNV-PASNLKSAIASVMQEEGYIKSFS VDG----I---A----ASKTLNIKLKYY---DNK-----------SVIEKLKRISKPSLRVYVSSSQMPSVMNGLGIVIV STPKGVMTGQTAYEQNIGGEVLCSVYMSNQNIRIKLKAFDHRLIDKSALEIVETAKRTGASVRGPIPLPTKKERFTVLTS PHVNKKAR-DQYELRTYVRLMDVISPTDKTVDALMKLDLAAGVDVAIKLERVLTGTVVSNNRNKTIAVLIERKVRHPIYK KYIKRSTKVHAHDEK--NKCALGDLVRVVEAKPFSKTKHWALLEVVEKS------------------------------- -MARSL-RKGPFIDE-HLIKKVLVAQE---KNDRK----PIKTWSRRSVVVPEMIGLTIAVHNGRVHVPVSINE-NMIGH KLGEFAITRTFKGHS------G---DR----KV--------- >GAMMA_Candidatus_Vesicomyosocius_okutanii_HA Concatenation of 2 sequences AQVIKRKPTSPGRRFVVSIVDKE-LHKG------------TS-YGPLTQNKNRINGRNNAGRITMRH-KGGGHKRR---- YRIIDFK-RN--K-DDITARVERLEYDPNRSANIALILYA-DGKRHYIIAPRGLSVGDMIVSGN-S-VA-IQVGNVMPLS NIPLGSIVHCIELRPMKGAQIARSAGTSAQLIAK--RGTYVTLRLRSGEVRKVLTDCRATIGEVSRSEHSLRKLGKAGAT -RWH-----GVR-P-TVRGVVMNSVDHPHGGGEGKT-S--GGR-HPVSP---WGTPTKGYKTR-SNKR-TD-K-LILRHR --------------------------------MAI---D-LVGQKIGMTRLIS-DDGS---------IMPVSVIKIEPNR IVQTR----TID----I--DGY--RAIQVTT-------GK--KISA----------AIKGHYK----------------- ---AS-QEIGLGLWEFKL-----EDNE----I-----TN---AT-SIDI--S-L-FGAGHYVDVIGKSKGKGFQGGVKLH NFQM-QDATHGNSISHRA-IGSTGQC-QEPG-RVFKGKKMAGHMGNKQVTQECLKVVKVDIEKS---------------- ----------VILVKGS-IPGAIKGFVKVS--MELKVLN-ISLNSL-NTVEVDDTIF----AR-DF-NQALVHQVTTAYM SGSRQGSKAQKNRSA--------VS-GGGKRPW---------AQKGTGRAR--------AGT---TR-GP----IW---- RSGGVTFATQ-P-RSYAQKVNKKMYKGAISIIFSELVRSE----------------R-LKVVKEF----DIK-E------ --VKTKLLM--TDELD--E---NLYLSSRNLYHVG-V---------------CDTQSIDPVSLIGYDN----VVVTELAL KKIESRLQEQYKNKI----SLILQKELGMSNPMQTPKIEKITINMGLG-NALGDKKILQSGLEEMSLISGQKPLTCNARK SVASFKLREGNPIGCKVTLRKQKMYEFLDRLVNITIPRIRDFRGLKT-TAFDGRGNYNMGITEQITFPEID-----FEKV TKIRGMDIAITTT-----------------------AKSDEDAKKLLAMFKFPFMSRVA-K--SSITIPTSVEVI-I--- -T-G--N-LMSVKGRLGQLNMSI--HP-C--VAIMNTNFDI--ITI----E-K--KEQRKAW-AQAGTARANTANLIQGV TEGWKKKLTLIGVGY--RAKVMG-KI--LDLT--LGFSHPINYKF-P-E-GIIVETP--S-QTEIIIKG-MDKQKVGQVA SEIRSYR------PPEPY---KGKGVRYIDEQVIHKETK----------MIQVQTRLKVADNSGGIKAMCIKVLG-SKRR Y--ANIGDVIKVSIKEVVPR-G-------KVKKGDVYDAVVVRTAHGVRRSDGSRIRFDSNAIVLLN-TKRE-PIGTRIF GPVTRELR-SAQFMKIVSLAPEVLMQ-L--NTLSPAQGE-KKSRKRVG-RGIGSGI-GKTCGSGHKGQKSRSGGF-N--- -KIGF-E-GGQMPLQRRLPK-VG--FSSVTLSEIITIDVFKAH-NLITVK---------VIL--SGE-I-T-R-A-VTL- TGIKVTKGAKLAIEAVKGSV-K---MMK--GRN---RGLA--TGHKVSFG----------EIGLQAV--GRCRLSARQIE SARRAMTRHV------KRQGKIWIRVFPDKPVTKKPLEVRMGKGK---------GSVEYWVAKIKP-GQMLFEM--QG-- VEETVAIEAFALASGKLPVKTTI-IKKQARLRRATKFRAKH----AKKDIERLCIHKTAQHIYAQIISS---C--GTKIL ASASTL-KAKL---------KNG-GNVDAAVKVGEAIAKA--ATSVK-VKKVAFDRSGFKYH--GRVKALADAAREGGLD F-------------------------------------------------------------MKE-VKAVHKYAKTSAFK ARLVADQIRLKSVEEALNILSFS---------------------------------NKKAAVLVKKVLNSVISN----A- EHND-GLDIDELFVTSIYIDEGSTMKRIRPRAKGRANRILKRTSHITVGIGKMQKIKSNDEIIIIAGK------DK-GSI GIVTKIVDS----KVL--VEGLNLAKKHVK----PN-PNK-GVT-GGITEIEMPLSISNVA-IYNPTT-------KK--A --DRVGIRT---SK--------NGKER---FFKSND---KSI--MGQKVNPKGIRLG--II-KDWDSKWYA------SSK D--YSKYLLSDIKVRNYL--FKKLI-----NASVSRVQIGRLV-N-NAKVTIYTARPGIVIGKKGADIEQLKLIVSKMVH INIEEIKK---PELDARLVAENIAQQLEKRVMYRRAVKRVLGNATRL-GAQGIKVMVSGRLNGAEIARSEWYREGRVPL- -HTFRADVDYSSYGAKTQYGVIGIKVWIFMSMSDPIADMLTRIRNAQLVKKKEVNV-PSSNLKFAIAGVMQQEGYIESFS VNG----V---V----ASKILKIKLKYY---DNK-----------PVIEKLKRISKPSLRVYVSNSKIPSVMNGLGIVIV STPKGVMTGQVALDQNVGGEVLCSIYMSNQNIRIKLKAFDHRLIDKSAVEIVETAKRTGASVRGPIPLPTKKERFTVLTS PHVNKKAR-DQYELRTYVRLMDVISPTDKTVDALMKLDLAAGVDVAIKLECVLTGTVVSSNRDKTITVLIERKVRHPIYK KYIKRSTKVHAHDDK--NECICGDLVRVVEAKPFSKTKHWSLLEVVERL------------------------------- -MARSL-RKGPFVDE-HLIKKVLAAQG---NNDRK----PIKTWSRRSVVVPEMIGLTIAVHNGRVHVPVSINE-NMVGH KLGEFAITRTFKGHF------G---DR----KA--------- >GAMMA_Cellvibrio_japonicus_Ueda107 Concatenation of 2 sequences MAIVKSKPTSPGRRFVVKVVNHD-LHKG------------EP-YAPLLDKKSKSGGRNNTGRITTRH-VGGGHKQH---- YRIVDFR-R--NK-DGIPATVERIEYDPNRTAYIALVVYA-DGERRYIIAPKGLSAGDKIESGN-A-AA-IKVGNTLPVR NIPLGSVIHCVELKPGKGAQLARSAGASAQLVAK--DGAYVTLRLRSGEMRKVLSDCRATLGEVSNTEHNLRSLGKAGAK -RWL-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGIPTKGYKTR-KNKRTDN---MIVRRR --------------------------------MTI---G-IVGRKTGMTRVFT-DDGV---------SIPVTVIEVEPNR VTQVK----TAD----T--DGY--SAVQITV-------GE--RVTK----------SEAGHFK----------------- ---AN-VEAGRSVWELRN--------NSQEAF-----EV---GA-SLTV--E-A-FSAGQFIDVTGTSKGKGYAGTVKRW NFGM-QDATHGNSRSHRV-PGSTGQC-QSPG-RVFKNKKMTGHMGAERVTVQNLEIVRVDAERN---------------- ----------LLLVKGA-IPGAPGGDVIVR--MELKIVN-PGGAQ--GTVNVSEVAF----GR-EF-NQDLVHQAVVAYM AGARQGTKAQKTRAE--------VS-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGVTFAAK-P-RDFEQKLNRKMYRAALQCILSELNRQD----------------R-LIVVESF----DVD-A------ --PKTKLIV--TEDLS--E---NLYLASRNLHKVG-V---------------SDVQGVDPVSLIGYDK----VVVTVPAL KKFEARLKELYTKEL----APKLKEELGLANVMEVPRITKITINMGVG-EAVGDKKVLENAVNDLVKIAGQKVVVTKSRK SIAGFKIRDGWPIGCKVTLRKDRMYEFLDRLIAVAIPRIRDFRGISP-KQFDGRGNFSMGVTEQIIFPEID-----YDKV DRLRGLDICITTT-----------------------ARTDEEGRALLKAFNFPFMSRVA-K--SPVEVPAAVTVT-L--- -N-G--Q-SLSVKGGKGTLALEV--HA-N--VEVKHEG-NV--LTF----T-P--RDGKQSD-ALAGTTRALVNNMVVGV SQGFEKKLTLVGVGY--RVKAEG-NT--VNLS--LGYSHPVNYVL-P-Q-GVSVETP--S-QTEIVLKS-ADKQLLGQVA AEIRAFR------EPEPY---KGKGVRYSDEVVLRKEAK----------MIQTESYLDVADNSGARRVMCIKVLG-SHRR Y--AAVGDIIKVTVKEAIPR-G-------KVKKGQVLKAVVVRTKKGVRRQDGSLIKFDDNAAVLLN-NQDA-PIGTRIF GPVTRELR-GEKFMKIISLAPEVLMR-L--NTLSPAPGR-IHAKKRVG-RGIGSGL-GKTAGRGHKGLKSRSGGS-V--- -RPGF-E-GGQMPLQIRLPK-YG--FTSIRLSELVDIETLKQA-GLISAK---------IFA--SGE-V-K-K-A-VTV- KGLAVTKGAKAAIEAAGGKV-K---QMK--GRN---RGLA-LRGSKVSFG----------DFGLKAT--GRGRITARQIE AARRAMTRHV------KRGGKIWIRVFPDKPITAKPLEVRMGSGK---------GGVEYWVAQIRP-GKVLYEM--DG-- VSEELAREAFALAAAKLPVTTTF-VKKEARLRRARRARAKI----RELGVTRLAIHRTPRHIYAQLISG---D--GSTVI ASASTL-DKDL-RS------GKT-GNADAAKAVGALIAER--AKAAG-VTQVAFDRSGFKYH--GRIKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARLSAQK ARLVADQIRGKGVEDALDILAFS---------------------------------TKKGAQIIKKVLESAIAN----A- EHNE-GADVDELKVKTIFVDEGVSLKRIKPRAKGRADRITKRTCHITVKVADMRKIKRDDEVIVIAGR------DK-GKR GKVVRVLAE-D--RLI--VSGINMIKKHQK----PN--PQLGVA-GGIVEKEAAIHASNVA-IYNPAT-------KK--A --DRVGFKI---LE--------NGKVR---VFKSNG---EAV--MGQKVHPNGIRLG--II-KKHTSVWYA------DGT D--YADKLNIDLKVRSYI--QEKLA-----SASVSRVDIERPA-N-TARITIHTARPGIVIGKKGEDVDKLRAEISKQVH INIEEIRK---PDLDAALVAQSVAQQLERRVMFRRAMKRAVQNAMRQ-GAEGIKIQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATAEASTTYGIIGVKVWIFMSMQDPLADMLTRIRNAQGVGKATVTM-PSSKLKVSVAKVLSDEGYINGFS VSE----S--------PKQELTVELKYF----EG-------K---PVIAELDRVSRPGLRNYAGKSALPTVRGGLGIAIV STSKGVMTDRAARAAGVGGEVLCTVFMQNQRIRIRLKAFDHKLIDASTQEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLLDIVEPTEKTVDALMKLDLAAGVEVQISLARTLTGKVVSDKMDKTITVLIERRVKHEVYG KYFTKSSKVHAHDEK--NECRIGDTVTVAESRPLSKTKTWALVKIEERA------------------------------- -MPRSL-KKGPFIDL-HLIKKVEAAIA---SNDRR----PIKTWSRRSMILPEMVGLTLAVHNGRQHVPVLVNE-EMVGH KLGEFAATRTYRGHA------A---DK----KAK------KR >GAMMA_Chromohalobacter_salexigens_DSM_3043 Concatenation of 2 sequences MAVVKTKPTSAGRRHVVKVVSDE-LHKG------------RP-YDGLLEKKSKSGGRNNNGRITTRH-VGGGHRQH---- YRVVDFK-R--NK-DGIAATVERLEYDPNRSANIALLKYL-DGERRYIIAPRGVKVGDSLESGV-N-AA-IKRGNALPLR NIPVGSTVHCIELKPGKGAQIARSAGASAQLVAR--EGNYATVRLRSGEMRKILAECRATLGEVGNSEHSLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGIPTKGHKTR-KNKR-TD-K-LIVRRR --------------------------------MTI---G-LVGKKSGMTRIFT-ENGA---------SVPVTVIEVEPNR VTRVK----TVE----S--DGY--SAVQVTS-------GS--RLTK----------AAAGQYK----------------- ---SG-VEAGRSLMEFRL--------AEGEEA----PEV---GG-NITV--S-L-FEAGQKVDVTGTSKGKGFQGAVKRW NFRT-QDNGHGNSLAHRA-PGSIGQC-QTPG-RVFKGKKMAGQLGNERVTVQSLEIVRVDAERN---------------- ----------LLLVKGA-VPGATDCEVIVR--MNLN----LAGADA-GTVEVSDATF----GK-EF-NESLVHQVVTAYF AAGRQGTRAQKTRSE--------VR-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----LW---- RSGGVTFAAR-P-QDYTQKVNRKMYRAAMRSILSELVRQE----------------R-LVVVDSF----EVD-A------ --PKTKLIV--TEDID--E---KLFLAARNIPYVD-V---------------VDVAAADPVSLVAFDK----VLVTVSAL RKFEANLKERYQNEV----AAQLQEQFSYANVMQIPRITKVTLNMGIG-DATSDKKLIDNAMGDLEKLSGQRPVITKARK SIAGFKVREGWPIGIKVTLRSERMWDFLDRLVNIAIPRVRDFRGLNP-KSFDGRGNYSMGVREQIIFPELE-----YDKI DRIRGLDVTITTT-----------------------ANTDEEGRALLSALNFPFMSRVA-K--YPVKLPSGVEVK-L--- -E-A--N-KLTVKGGQGTLSMTV--HS-D--VTIGQEE-GQ--LTF----N-P--SESAKSW-AMVGTTRALVQNIVTGV SEGFTKSLEINGVGY--RAQASG-NT--LNLT--LGFSHPVEYKL-P-E-GVTAETP--K-NTTIVLKS-ADKQQLGQVA AEIRAFR------PPEPY---KGKGIRYGDEEVRRKEAK----------MIQTQTMLDVADNSGARRVQCIKVLG-SHRR Y--ARVGDVIKVTVKEAIPR-G-------KVKKGQVLKAVVVRTKSGVRRTDGSLIRFDGNAAVLLH-NANEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMK-L--NNLSPAPGS-KHAEKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGS-V--- -KPGF-E-GGQMPLQRRLPK-YG--FTSVRLAELVDLESLKKA-NVLKAK---------VIL--SGE-L-N-K-A-VTV- RGLKVTKGARDAIAAAGGKV-K---VQK--GRN---RGLA-HRGSKVSFG----------EYGLKAT--GRGRITARQIE AGRRAITRHV------KRGGKIWIRVFPDKPITEKPLEVRMGKGK---------GSVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFDLAAQKFPVSTTF-VKKEARLRRARRARAKI----REQGVSRLSVNRTPRHIYAQIISP---D--GGQVL ASASTL-DKSL-RE------GST-GNSDAAAKVGALIAER--AKEAG-ITEVAFDRAGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VTAKLRGARLSAQK ARLVADLVRGKPVAEALDVLAYS---------------------------------PKKAAKVVKKVLQSAIAN----A- EENN-GMDIDELRVSTICVDEGMTLKRIQPRAKGRADRILKRTCHITVKVAEMRKIKRDDEVIVIAGK------DK-GKR GTIKRVLQDGC---YV--VSGVNMIKRHTK----PN--PMQGKQ-GGIVEREAPIHASNVA-IFNQET-------GK--A --DRVGFQI---QE--------DGKVR---IYKSTQ---KQI--MGQKVNPTGIRLG--IV-KDHRSVWYA------ERG A--YADKLNNDLEVRRFL--EQRLK-----NASVSDITIERPA-N-NARITIHTARPGIVIGKKGEDVDRLRRDVSEMVH VNIEEVRK---PELDAQLVAQNVCGQLERRVMFRRAMKRAVQNAMRL-GAGGIKIQLSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWVFMSMQDTLADMFTRIRNAQMATKETVTM-PSSNLKTEVARVLKQEGYINDFT VTE--------G----AKPQLAVTLKYF----EG-------K---PVIEHIQRFSKPSLRSYKGKDALPKVADGLGIAIV TTSQGVMTDRAARQAGVGGEVICTVFMQNQKIRIRLKAFDHRLIDQSAQEIVDTAKRTGAQVRGPIPLPTNRERYTVLIS PHVNKDAR-DQYEIRTHKRVLDIVEPTEKTVDALMKLDLAAGVDVQIKLARTLTGKVVSDKMDKSVVVQIERRVRHPIYD KYVKRSTKLHAHDEA--NQARVGDTVSIEECRPISKLKAWTLVEVVEQA------------------------------- -MPRSL-KKGPFIDL-HLLKKVETAVE---KSDRK----PIKTWSRRSMILPNMVGLTIAVHNGRQHVPVHVSE-EMVGH KLGEFAATRTYRGHA------A---DK----KAK------R- >GAMMA_Citrobacter_koseri_ATCC_BAA-895 Concatenation of 2 sequences MVNPE-------------------LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEY-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGG-VPGATGCDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VNKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGVDGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-TEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNIA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGTGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Colwellia_psychrerythraea_34H Concatenation of 2 sequences MAIVKCKPTSPGRRHLVKVVNKE-LHTG------------KP-YAPLLDTKSKSGGRNNNGRITVRH-IGGGHKQH---- YRIVDFK-R--LK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYILAPKGLSAGDSILSGV-G-AP-IKPGNTMPLR NIPLGSVIHAIELKPGKGAQIARAAGTYAQLVAK--DGAYVTLRLRSGEMRKIESDCRATLGEIGNSEHMLRSLGKAGAS -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGKT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-FIVRRR --------------------------------MTI---G-LVGRKVGMTRVFT-EDGV---------STPVTVIEVEANR VAQVK----TVD----N--DGY--SALQVTT-------GK--RVTK----------PAAGHFK----------------- ---AG-IEAGRGLWEFRL------NENEGSDI-----EA---GS-EITV--E-V-FNDTKLVDVTGTSKGKGFQGGIKRW NFTM-QHATHGVSLSHRS-NGSLGQC-QTPG-RVFKGKKMSGHMGAVRCTTQNLELVRVDAERN---------------- ----------LLLIKGA-VPGAINGNVIIK--MELSLKD-AS-----GALEVSEATF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---TR-GP----IW---- RTGGVTFAAK-P-QDHSQKVNRKMYRGAIASILSELVRQE----------------R-LVVVENF----SVE-T------ --PKTKLIV--TKEVD--E---NLFLSARNLYKVD-V---------------RDVAAIDPVSLVGFEK----VLITADAV KEIEAKLHDLYKDTV----VAELQKQFGYKSVMQVPRIEKITLNMGVG-EAISDKKVLEHATNDLTAISGQKPITTVARK SVAGFKIREGYPIGTKVTLRGERMWEFLERLISISIPRIRDFRGLNP-KSFDGRGNYSMGVREQIIFPEIE-----YDKI DKIRGLDITITTS-----------------------AKDNEEGLALLSAFDFPFMSRVA-K--APVVVPAGVTIT-L--- -S-G--Q-DITVKGPIGELSRTI--HS-D--VVVSQEE-NN--IIT----N-I--VADKGAW-AQAGTTRALINNMVEGV SKGFEKKLVLQGVGY--RAKAAG-KS--LDLS--LGFSHPIKHAI-P-E-GITCETP--S-QTEVTLKG-CDKHLVGQTA ANIRAYR------KPEPY---KGKGVRYVDEYVRRKEAK----------MIQMQSQLNVADNSGAKRVQCIKVLG-SHRR Y--ARIGDIIKVAVKEASPR-G-------KVKKGDVHTAVVVRTKKGVRRTDGSAIRFDENAAVMLN-ANLQ-PIGTRIF GPVTRELR-NEKFMKIVSLAPEVLMH-L--NTLSPAPGS-HKARKRCG-RGIGSGI-GKTGGRGHKGQKSRSGGS-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLHELVDIHALKDA-GLITVK---------VML--SGE-I-T-R-P-ITL- RGIAVTKGAQAAIEAAGGKV-K---QFK--LRN---RGLA-HVGSSVSFG----------TFGLKSM--ERGRMTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITKKPLEVRMGKGK---------GSVEYWVCQILP-GRVLYEM--EG-- VSEEIAREAFALAASKLPFKTTF-VKRSSRLRRAKRARAKI----SELGANRLVIFRTPRHIYAQLIAP---T--GSEVI ASASTL-DKEV-SAQI----EKT-GNVAAATAVGKAIAER--AVAKG-ITKIAFDRSGFLYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------MQ-AIAIHKFARGSAQK ARLVADQIRGVNVEKALEILTFS---------------------------------NKKAAELVKKVLNSAIAN----A- EHNE-GADIDELFVKTILIDDGPTMKRIMPRAKGRADRIIKRTSHITVIVSDASKIRRDDEVIILAGK------DK-GKT GKVTKVLVEDG--KVF--VEGINLIKKHTK----PV-PQL-QQP-GGIVEKEAPLQVSNVA-IVNSAT-------GK--A --DRVGFRI----E--------DGKVR---FFKSNN---ELI--MGQKVNPTGIRLG--IT-KPFASTWFA------SNK D--FASNLDGDHKVREFL--KEKLK-----RASLSKVVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRLAVSKIAQ INIAEVRK---PEMDAQLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVQVSGRLGGADIARAEWYREGRVPL- -HTLRADIDYAIARGNTTYGVIGIKVWIF-MMTDPIADMFTRIRNGQSAAKVAVQM-PSSKVKVAIATLLKEEGYISEFS VSG----E--------VKPELAVTLKYF----EG-------K---EVIEKIKRVSRPGLRIYKSCDELPKVLAGMGIAII STSKGLMTDRAARSAGIGGEVLGFVEMSNQRIRIRLKAFDHRLIDQSTAEIVDTAKRTGAQVRGPIPLPTRKERYTILTS PHVNKDAR-DQYEIRTHKRMIDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGVVVSNKMDKSIVVLIERRVKHPMYG KYMTRSTKLKAHDET--NVCNEGDLVTITEVAPISKSKNWKLVDVITKA------------------------------- -MPRSL-KKGPFIDL-HLLTKVEKAVE---SGNKK----PIKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTYRGHV------A---DK----KAK------K- >GAMMA_Coxiella_burnetii_CbuG_Q212 Concatenation of 2 sequences MALVKTKPTSPGRRFVVKVVHPE-LHKG------------DP-YAPLVESKNRINSRNNQGRITVRR-RGGGHKRN---- YRIIDFK-R--DK-EGIEGKVERLEYDPNRSAHIALVLYP-DGERRYIIAPKGVHKGSKVVSGR-E-AP-IRPGNCLPLQ NIPLGATIHNIELKPGKGAQLVRSAGASAQLAAK--EGIYAIIRMRSGETRKILAVCRACIGEVSNSEHNLRSLGKAGAK -RWR-----GRR-P-TVRGVAMNPVDHPHGGGEGKT----SGGRHPVSP---TGKPTKGYKTR-RNKRTSN---MIIRDR --------------------------------MSI---G-LIGRKCGMTRIFT-ETGS---------SIPVTVVEVILNR ITQVK----TVE----T--DGY--RAFQVAY-------GK--KVNK----------PLAGHYK----------------- ---AA-VEAGNALREFRL------GNEELTEA-----KA---GD-ELKV--D-I-FKEGQVVDVRGLTRGKGFAGTVKRH NFRT-QDATHGNSLSHRA-PGSIGQC-QTPG-RVWKGKKMAGQLGNVYCTVQSQEIIKVDVERN---------------- ----------LLLIKGA-LPGAPGGEVIIT-MMELPVNS-FDKKEA-STLTVADSAF----GS-EY-KEGLVHQVVNAYL AGGRAGTKAQKTRRE--------VS-GGGAKPW---------RQKGTGRAR--------AGS---SR-SP----LW---- RSGGVAFAAK-P-RDFTQKVNRKMYRSAMASILSELIRRE----------------Q-LVVVDSL----KLN-E------ --PKTRLII--IDGDD--R---NINLASRNMVGVS-V---------------CDALHVDPVSLVAAEN----IVVTVDAV KRLEVELQELYKKTI----TPALQKEFGFKSVMAVPRLEKITLNMGLG-EAVADKKVIERAMDDMIKISGQKPLITYARK SEAGFKIRAGWPIGCKVTLRRDRMYEFLKRLISIAIPRIRDFRGLSP-KSFDGRGNYSLGIREQIVFPEIQ-----YDKV DAIRGMDITITTT-----------------------ARTDEEGRALLKAFGFPLVSRVA-K--NPIKIPTGVEVN-V--- -A-G--Q-QITVKGKLGTLTRVI--HR-A--VKVTKTD-AE--LQT----I-C--ANDPGSN-ALAGTARAVLANMVQGV HTGFQRKLVMVGVGY--RAKAED-KK--LNLT--VGLSHPVNIEM-P-E-GITVETP--S-QTEIIVKG-ADKQRVSQVA ANIREIR------PPEPY---KGKGIRYDNERVILKEAK----------MIQTQSIVDVADNSGARRVMCIKVLG-SKRR Y--ANIGDVIKVSIKEAIPR-G-------KVKKGDVMHAVVVRTRKGVRRNDGSLIRFDNNAVVLLN-NQLQ-LVGTRVF GPVVRELR-TDKFMKIISLALEVLMQ-L--NDLKPAKGA-RHQKLRVG-RGIGSGK-GKTAGRGHKGQHSRAGGY-H--- -KVGF-E-GGQMPLQRRVPK-FG--FTSVRLGELVDLASLKAA-NIISVK---------IFA--AGK-L-E-K-P-VTI- RGLRVTKGVKAAVEAAGGKI-K---DFK--GRN---RGVA-SRGNRVSFG----------EFGLKAT--ECARITARQLE AARRTIARHI------KRGGKITIRIFPDKPITKKPLEVRQGKGK---------GSVEYWVALVQP-GRMIFEI--EG-- VDEALAREAFSRAAAKLPLKCLF-VKQEKRIRRARRTRAKI----KELGAVRLCVHRSLNHIYAQLISP---R--DSKVL VCASTL-EKEV-RSQI----KHG-GNIQAATAIGKLIAQR--AKKAG-VTKVAFDRSGYKYH--GRVRALAEAVREGGIE F--------------------------------------------------------------ME-VAAKLKYARISAQK ARLVADQVRGLGAEQAVNLLRFS---------------------------------NKKAAALMKKVLDSAIAN----A- EHNE-GADIDELKVSTVMVDEGPSARRFHARARGRANQILKRTCHITVKVSDIKKIKKDDTVIVITGR------DK-GRQ GKVLKVLPN-S--RLL--VEGINLVKKHVK----PN--PNKNEQ-GGILERELSIHVSNVA-IYNPAA-------KK--A --DRVGIKT---LE--------DGKVR---IFKSNG---EVI--MGQKVNPVGMRIG--IT-RDWTSNWYA------DKK D--FADRLNEDLNVRQLL--QKRLK-----GAAVSRIQIERPA-R-NAKIIIHSARPGVIIGKKGGEIEALRDEISKVVH ITIEEVRK---PELDAKLVAENIAQQLERRVMFRRAMKRAVQNTLRQ-GALGVKISVSGRLGGAEIARTEWYREGRVPL- -HTFRADIDYATASAKTTYGIIGVKVWIFTMMQDPISDMLTRIRNAQAVRKKEVVM-PRSKLKMSIANVLKEEGYIVDYR EEG----D---S----TKPQLVITLKYH----EG-------E---SVISEIRRVSSPALQVYKSKDELPKVKNGLGIAII STSKGVMSDRQARRLGEGGEVLCYVSSDNQRIRIRLKAFDHRLIDRSTREIVETARRTGAIIRGPILLPTKIERYTVLIS PNIDKDAR-DQYEIRTHKRLVDISEPTDKTVDALMKLDLAAGVDVQIELVRSLMGTVVSNKMNDTVVVRVERRVKHPKYG KFIKRSTKIHAHDKG--NECQIGDIVTIRECRPISKTKSWTLVKINERA------------------------------- -MPRST-NKGPFVDH-HLMKKVDQAQK---EGSKR----PIKTWSRRSMVVPEMVGLTIAIHNGRQHVPVYISE-NMVGH KLGEFAITRTFRAHS------G---DR----KAK------KE >GAMMA_Coxiella_burnetii_RSA_331 Concatenation of 2 sequences MALVKTKPTSPGRRFVVKVVHPE-LHKG------------DP-YAPLVESKNRINSRNNQGRITVRR-RGGGHKRN---- YRIIDFK-R--DK-EGIEGKVERLEYDPNRSAHIALVLYP-DGERRYIIAPKGVHKGSKVVSGR-E-AP-IRPGNCLPLQ NIPLGATIHNIELKPGKGAQLVRSAGASAQLAAK--EGIYAIIRMRSGETRKILAVCRACIGEVSNSEHNLRSLGKAGAK -RWR-----GRR-P-TVRGVAMNPVDHPHGGGEGKT----SGGRHPVSP---TGKPTKGYKTR-RNKRTSN---MIIRDR --------------------------------MSI---G-LIGRKCGMTRIFT-ETGS---------SIPVTVVEVILNR ITQVK----TVE----T--DGY--RAFQVAY-------GK--KVNK----------PLAGHYK----------------- ---AA-VEAGNALREFRL------GNEELTEA-----KA---GD-ELKV--D-I-FKEGQVVDVRGLTRGKGFAGTVKRH NFRT-QDATHGNSLSHRA-PGSIGQC-QTPG-RVWKGKKMAGQLGNVYCTVQSQEIIKVDVERN---------------- ----------LLLIKGA-LPGAPGGEVIIT--MELPVNS-FDKKEA-STLTVADSAF----GS-EY-KEGLVHQVVNAYL AGGRAGTKAQKTRRE--------VS-GGGAKPW---------RQKGTGRAR--------AGS---SR-SP----LW---- RSGGVAFAAK-P-RDFTQKVNRKMYRSAMASILSELIRRE----------------Q-LVVVDSL----KLN-E------ --PKTRLII--IDGDD--R---NINLASRNMVGVS-V---------------CDALHVDPVSLVAAEN----IVVTVDAV KRLEVELQELYKKTI----TPTLQKEFGFKSVMAVPRLEKITLNMGLG-EAVADKKVIERAMDDMIKISGQKPLITYARK SEAGFKIRAGWPIGCKVTLRRDRMYEFLKRLISIAIPRIRDFRGLSP-KSFDGRGNYSLGIREQIVFPEIQ-----YDKV DAIRGMDITITTT-----------------------ARTDEEGRALLKAFGFPLVSRVA-K--NPIKIPTGVEVN-V--- -A-G--Q-QITVKGKLGTLTRVI--HR-A--VKVTKTD-AE--LQT----I-C--ANDPGSN-ALAGTARAVLANMVQGV HTGFQRKLVMVGVGY--RAKAEG-KK--LNLT--VGLSHPVNIEM-P-E-GITVETP--S-QTEIIVKG-ADKQRVSQVA ANIREIR------PPEPY---KGKGIRYDNERVILKEAK----------MIQTQSIVDVADNSGARRVMCIKVLG-SKRR Y--ANIGDVIKVSIKEAIPR-G-------KVKKGDVMHAVVVRTRKGVRRNDGSLIRFDNNAVVLLN-NQLQ-LVGTRVF GPVVRELR-TDKFMKIISLALEVLMQ-L--NDLKPAKGA-RHQKLRVG-RGIGSGK-GKTAGRGHKGQHSRAGGY-H--- -KVGF-E-GGQMPLQRRVPK-FG--FTSVRLGELVDLASLKAA-NIISVK---------IFA--AGK-L-E-K-P-VTI- RGLRVTKGVKAAVEAAGGKI-K---DFK--GRN---RGIA-SRGNRVSFG----------EFGLKAT--ECARITARQLE AARRTIARHI------KRGGKITIRIFPDKPITKKPLEVRQGKGK---------GSVEYWVALVQP-GRMIFEI--EG-- VDEALAREAFSRAAAKLPLKCLF-VKQEKRIRRARRTRAKI----KELGAVRLCVHRSLNHIYAQLISP---R--DSKVL VCASTL-EKEV-RSQI----KHG-GNIQAATAIGKLIAQR--AKKAG-VTKVAFDRSGYKYH--GRVRALAEAVREGGIE F--------------------------------------------------------------ME-VAAKLKYARISAQK ARLVADQVRGLGAEQAVNLLRFS---------------------------------NKKAAALMKKVLDSAIAN----A- EHNE-GADIDELKVSTVMVDEGPSARRFHARARGRANQILKRTCHITVKVSDIKKIKKDDTVIVITGR------DK-GRQ GKVLKVLPN-S--RLL--VEGINLVKKHVK----PN--PNKNEQ-GGILERELSIHVSNVA-IYNPAA-------KK--A --DRVGIKT---LE--------DGKVR---IFKSNG---EVI--MGQKVNPVGMRIG--IT-RDWTSNWYA------DKK D--FADRLNEDLNVRQLL--QKRLK-----GAAVSRIQIERPA-R-NAKIIIHSARPGVIIGKKGGEIEALRDEISKVVH ITIEEVRK---PELDAKLVAENIAQQLERRVMFRRAMKRAVQNTLRQ-GALGVKISVSGRLGGAEIARTEWYREGRVPL- -HTFRADIDYATASAKTTYGIIGVKVWIF-MMQDPISDMLTRIRNAQAVRKKEVVM-PRSKLKMSIANVLKEEGYIVDYR EEG----D---L----TKAQLVITLKYH----EG-------E---SVISEIRRVSSPALQVYKSKDELPKVKNGLGIAII STSKGVMSDRQARRLGEGGEVLCYVSSDNQRIRIRLKAFDHRLIDRSTREIVETARRTGAIIRGPILLPTKIERYTVLIS PNIDKDAR-DQYEIRTHKRLVDISEPTDKTVDALMKLDLAAGVDVQIELVRSLMGTVVSNKMNDTVVVRVERRVKHPKYG KFIKRSTKIHAHDKG--NECQIGDIVTIRECRPISKTKSWTLVKINERA------------------------------- -MPRST-NKGPFVDH-HLMKKVDQAQK---EGSKR----PIKTWSRRSMVVPEMVGLTIAIHNGRQHVPVYISE-NMVGH KLGEFAITRTFRAHS------G---DR----KAK------KE >GAMMA_Dichelobacter_nodosus_VCS1703A Concatenation of 2 sequences MAIINHKPTSPGRRGRVDVTRPE-LHKG------------KP-FAALVEKKTRGSGRNNAGRITVRH-KGGGHAQK---- YRLIDFC-RN--K-DGIDAVVERLEYDPNRTSFIALLRYS-DGERRYVIAARDMKAGDIVRNGE-D-AP-IKDGNCLPMR NIPVGSTIYCVELKPGKGAQLARSAGASAQMVAR--EGKYVTVRLKSGERRLVLADCRAVLGEVSNHEHSLRSYGKAGAK -RWL-----GIR-P-TVRGVVMNPVDHPHGGGEGRT-A--SGR-HPVSP---WGLPTKGYKTR-NNKR-TD-S-LIVQRR --------------------------------MTM---G-LVGQKVGMTRIFD-EEGT---------ASAVTVIEIQPNI ISQIK----TDE----T--DGY--HAVQVSV-------GH--RTTK----------ALAGHFK----------------- ---AN-ISAAALVKEFRV------DSEEIAKY-----EV---GK-PVEL--A-I-FEQGQRVDVRARSIGKGYAGTIKRH NFRG-QRKTHGNSVSHRV-PGSIGQN-QTPG-RVFKGKKMSGHMGNKMCSVQNIEIARIDVERN---------------- ----------LLLLKGS-VPGAKGGYVVIR--MEIQFTN-TA-----DRISVADSVF----SA-AY-NEPLIHQVVVAYL AGARQGTKAQKTKAE--------VS-GGGVKPW---------KQKGTGRAR--------AGS---IR-SP----LW---- RTGGKIFAAK-P-RSYVQKVNRKMYRSALCSIFSELNRIG----------------R-FIAVNAL----ELT-E------ --PKTKLLI--TESEN--I---NIFLASRNLPNVT-V---------------IDVQEINPALLLKHEK----VIVDKAAL EKINARLQKFYKEEV----IKKLQSELGLKNVMEVPRLEKITINMGVG-EAVNDKKIMDNAVRDLALISGQKPVVTKSKK SIAGFKIRDGWAIGCKVTLRRQQMYEFLDRLINVSLPRTRDFRGLNP-KSFDGRGNYTFGVKEHIIFPEID-----FEKT DAIRGMDITFTTS-----------------------AKDNAQAKALLEAFGFPFMSRIG-K--QPVSIPSGVECS-I--- -K-G--Q-LLSVKGKKGQMTLDL--HP-F--TKITSED-GF--LKL----N-P-VVEDRDHW-AICGTMRALVHNMVVGV TQGFEKKLLLMGVGY--RAQAQG-QK--LTLV--LGFSHPVEYAV-P-Q-GITIETP--T-PTEIIVKG-FDKQLVGEVA AKIRAYR------PPEPY---KGKGVRYAGEYVMIKEAK----------MIQMQSRLSVADNSGARELQCIKVLG-SHRR Y--AGIGDVIKVSVKDAMPR-G-------RVKKGDVYNALIVRTKKGVRRRDGSVLRFDGNAAVLLN-SKLE-PIGTRVF GPVARELR-SEKFMKIISLAPEVLMR-F--NELQPAKGS-RFAGKRLG-RGIGSGL-GKTSGKGHKGQKARSGGY-H--- -KVGF-E-GGQMPLQRRLPK-RG--FRSIRLSELIDLNALKAA-GLASAK---------VYL--NGT-I-S-K-A-VTL- RGVSISAGAKAALEAAGGSV-K---QQK--GRN---RGLA-QSGNTVSFG----------DYGLKAT--TRGRLTARQIE AARRAINRHV------KRGGKVWIRVFPDVPVTNKPLEVRQGKGK---------GNVEYWVAKVQP-GTVLYEM--EG-- VTEELAREAFRLAAAKLPVQTTF-EKKINRIRRGKRTRLNI----RESGKPSLIVNKTPRHIYAQIISG---E--GNKVL ASISTL-NKEV-ADAV----HYT-GNIESATKVGQMIAEK--AKSLG-IESLAFDRNGFRYH--GRVKALADAARAAGLQ F--------------------------------------------------------------MQ-SIAKLRAARISAQK ARLVADQIRGKHVNDAVEILTFS---------------------------------QKKAAAIILKVLNSAIAN----A- ENNE-GADIDELHVAEIQVGEGMTMKRFRARAKGRGNRICKRTSNIFVRVQEMKRIKKGDEVIVIAGRSE----NK-GKR GKVVAVKDD----TVI--IEGINQVSKHVR----PN-PQL-GIE-GGIVKKEAGIHISNVM-LFNAET-------GK--R --DRVGFKI----E--------DGKFR---YYKSTG---KRI--MGQKIHPIGFRLG--VS-KDWTSKWYA------EGT D--YANYLEKDFEVREFL--RKKLA-----HASVSKIQIERPR-N-GAQITIFTARPGIVIGKKGEDIEILKKEVGKITS INIEEIRR---PELDSYLVADNIAKQLERRVMFRRAMKRAVASTMRL-GAVGVKVSISGRLNGAEIARTEWYREGRVPL- -HTLRADIDYGLAEAYTTYGVIGVKVWIF-MLMDPVADMLTRVRNAQRVGRSFVIM-PSSNQKKAIAEVLKEEGYIQSFE IKG----D--------KKPELTIYLKYY----QG-------R---PVIETIKRVSRPGLRIFRNKDQLPRVQSGLGIAII STSKGVMSDHKARELGVGGEVICMVAASTQKIRIRLKSYDHRLIDASAKQIVETAKRAGAQVKGPIPLPVKKEIYTVLIS PHVNKDAR-DQYEMRTHKRIMDIIDPTDKTVDALMKLDLAAGVDVKIELHRILQGEVVSNKSDKSITVTVVRYVKHPLYG KYIKRTLRCHAHDEN--NECNIGDVVRISQSRPISKTKTWRLVEIVERA------------------------------- -MARSL-KKGFFIDL-HLAHKVDVAVE---TKSKK----PIKTWSRRSMIIPDMIGLTIAIHNGKQHVPVLITE-DMIGH KLGEFAPTRNYRGHT------A--ADK----KGK-------- >GAMMA_Enterobacter_sakazakii_ATCC_BAA-894 Concatenation of 2 sequences MVNPE-------------------LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EEGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ADGEEY-----TV---GQ-SISV--E-L-FAEVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTQFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVIPAGVDVK-L--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAIKG-NV--VNLS--LGFSHPVDHQL-P-A-GITAECP--S-QTEIVLKG-ADKQLIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVVRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVL-------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--NKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKGVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKKKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Enterobacter_sp_638 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLVEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPATVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAVQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-DISV--E-L-FAEVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSNLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVETF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VSKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFLERLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------ANSDEEGRALLAAFDFPFMSRVA-K--APVVIPAGVDVK-I--- -D-G--Q-VITIKGKNGELTRTL--NN-A--VEVKHAD-NA--LTF----G-P--RDGVDGW-AQAGTARALLNSMVVGV TEGFTKKLQLVGVGY--RAAIKG-NA--VGLS--LGFSHPVEHPL-P-A-GITAECP--T-QTEIVLKG-ADKQLIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLTVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-TEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-S-T-P-VTV- RGLRVSKGARAAIEAAGGTI-K---VHK--GRN---RGLA--QGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFGLAAAKLPIKTTF-VKKSARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-TEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKVVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TLAQHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVFVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KII--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-LFNTVT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSAKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKKKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERIVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIHECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Erwinia_carotovora_atroseptica_SCRI1043 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLVEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGSYVTLRLRSGEMRKVESDCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVSP---WGLQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----DLA----N--DGY--RAVQVTA-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRTLREFRL--------SEGEEF-----TV---GQ-SISV--E-I-FADIKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRA-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEQF----SLE-A------ --PKTKLII--TGELD--E---NLFLAARNLYKVD-V---------------RDAAAIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFLERLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFNFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-DISIKGKNGELSRKI--HN-A--VEVKQAD-NA--LTF----A-P--REGVDGW-AQAGTTRALLNAMVIGV TEGFTKKLQLVGVGY--RAAVKG-NM--VNLS--LGFSHPVEHAL-P-A-GITAECP--S-QTEIVLKG-ADKQVIGQVA AELRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRLG-RGIGSGL-GKTGGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NVIGAK---------VIL--SGE-V-A-R-P-VTI- RGLRVTKGARAAIEAAGGKI-K---VHK--GRN---RGLA--QGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFQLAAAKLPIKTTF-VKKAARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KST-GNKDAATAIGKAIAER--ALEKG-IKNVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHCHARSSAQK VRLVADLIRGKKVSQALEVLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSASK---VI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNLA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWYA------NTK E--FADNLDSDFKVRKYL--TKELE-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANVLKEEGYIEDFK IEG----D--------TKPVLELELKYF----QG-------K---AVVESIQRISRPGLRIYKRKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSMVVAIERFVKHPLYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Erwinia_tasmaniensis_Et1/99 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNLE-LHKG------------KP-FAPLVEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPATVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQIARSAGTYVQIVAR--EGSYVTLRLRSGEMRKVESDCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVSP---WGLQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----GLE----N--DGY--TAIQVTT-------GA--KVTK----------PAAGHFK----------------- ---AG-VEAGRGLWEFRT--------AEGAEF-----TV---GQ-SINV--D-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-S-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEQF----SLE-A------ --PKTKLII--TGELE--E---NLFLAARNLYKVD-V---------------RDAAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFSYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGMDITITTT-----------------------AKSDDEGRALLAAFNFPFMSRVA-K--APVVIPAGVEVK-L--- -D-G--Q-VISIKGKNGELTRTL--NN-A--VEVKHAD-NT--LTF----A-P--REGADGW-AQAGTSRALLNAMVIGV TEGFTKKLQLVGVGY--RAAVKG-NA--VSLA--LGFSHPVEHAL-P-A-GITAECP--T-QTEIVLKG-ADKQLIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-TEKFMKIISLAPEVLMR-L--NTLSPADGS-KHAPKRLG-RGIGSGL-GKTGGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--SGE-V-S-A-P-VTI- RGLRVTKGARAAIEAAGGKI-K---VHK--GRN---RGLA--QGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-GEQL----KYT-GNKDAAAAVGKAVAER--AIEKG-ITGVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLVRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KII--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAALQISNVA-LFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQSANKVAVTM-PSSKLKLAIANVLKEEGYIEEFK IEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVIIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKALE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Escherichia_coli_ATCC_8739 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Escherichia_coli_K12 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Escherichia_fergusonii_UMN026,_ATCC_35469 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Francisella_philomiragia_philomiragia_ATCC_25017 Concatenation of 2 sequences IEIKKAKPTSPGRRHVVSVKNTE-LHTG------------KP-FKGLVEVKKSKAGRNNTGRITVRH-QGGGHKQH---- YRIVDFK-R--NK-DDIVARVERIEYDPNRSANIALVLYA-DGERRYIIAPKGLKKDMSVVSGE-K-VD-VAVGNCMPLR NIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGK--DNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGIPTKGYKTR-KNKRSNK---LIVQKR --------------------------------MSL---G-LVGRKCGMTRIFT-EDGV---------SIPVTVVQVESNK VTQIK----TTE----T--DGY--NAIQVTT-------GF--KVNK----------PMAGHYK----------------- ---AS-VEPGRGLWEFAI--------DNASDY-----EV---GA-SIDA--T-I-FEAGQKVDVRGVSKGKGFQGGVKRH NFAT-QDATHGNSLSHRV-HGSTGQN-QTPG-RVFKNKKMAGHLGSENVTIQSLEVVRVDAENG---------------- ----------LLLLKGG-IPGSVGGDVIVT--MDLNIKS-LAGAEA-GVVGVAEGVF----AA-DY-NESLIHQVVVAYM AGARQGTKAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IF---- RKGGVTFAAK-P-KSYKQKVNRKMYSGAVKSILSELVRSD----------------R-MTVVESL----RLE-T------ --PKTKLFVVGVEEFN--E---NLYLSSRNLKNVA-V---------------CDSVEINPVSLVCFEN----VVFTKQAI KEIEARLKDYYQNEV----VAKLKSELNLDNIMEVPAIKKITLNMGVG-DAAKDKKIMTFALNDLTAIAGQKPVVTMSKK SIAGFKIRDGWPIGAKVTLRGERMYEFLDRLITIAIPRIRDFRGLSA-KSFDGRGNYSLGMKEQISFPEID-----YDKI DSIRGLDISITTT-----------------------AKNDDQGRALLKAFGFPFMSRIG-K--KPVAIPSGVTIN-V--- -A-A-GN-QVEVKSTKATLNKTF--SS-D--VTFNIED-GV--VTV----T-P--KNNKNAI-AQSGTARAILNNMVEGV SKGFERKLKIIGVGY--RAKAQG-SE--LNLT--LGFSHPVVYKL-P-Q-GITAETP--A-PTEIILKG-ADKEVLGKVA SEIREYR------KPEPY---KGKGVRYEDEYVAKKEAK----------MIQMQTELQVADNSGAKRVECIKVLG-SHRR Y--ASVGDVIKVTVKEAAPR-G-------KAKKGSVYNAVVVRTAKGVRRKDGSKVRFDDNAAVLLN-NNGQ-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NTIAPAAGS-KSAPKRLG-RGIGSGL-GKTSGKGHKGQKARSGGY-H--- -KVGF-E-GGQMPIQRRLPK-FG--FTSIRLHELVTVDTLKDS-GLIRVK---------IIA--SGE-I-Q-K-A-VSL- KGIACTKGAKEAIEKAGGKV-K---QQK--MRN---RGLA-HRGNKVSFG----------EFGLQAT--SRGRVTARQIE AGRRAISRHI------KRGGKIWIRIFPDKPITQKPLEVRMGKGK---------GSVEYWVAQIQP-GRVLYEI--TG-- VKEELAREAFARAAAKMPVQTTF-VKKTARLSRSKRTRIKL----KELGHTRLCVYRTPRHVYAQVISG---D--GSTVL AAASTV-EKDV-KAKC----KYT-GNVNSAAIVGEVIANR--CKEKG-ISQVAFDRSGYKYH--GRVKALAEAAREHGLQ F--------------------------------------------------------------ME-VQAKLKFAKISAQK CRLVADQIRGLPVEKAINLLTFS---------------------------------NKKAAVLIKDVLNSAIAN----A- EHND-GMDVDSLFVSTVFVDEGPTMKRFEARAKGRGNRILKRTSHITVKVAEMNRLKKGDDVIVIAGK------DK-GRR GVVKSFAKGGS--LVL--VEGINIVKKHVK----PN--PNRGVE-GGVVEKELPVDASNVA-IFNPAT-------EK--A --DRVGYKF---VD--------EKKVR---YFKSNG---ELV--MGQKVNPNGIRLG--IV-KEHNSTWYA------DSS D--YATKLNEDIKVREFL--HKKLA-----SAAVSKIQIERPA-Q-NAKITIHTARPGIVIGKKGEDVEKLRADVNKLVQ INIEEVRK---PEIDAKLVADSVAQQLEKRVMFRRAMKKAMQAAMKS-GAKGIKIMVSGRLGGAEIARSEWARDGRVPL- -QTFRADVDYATSKALTTYGIIGVKVWIYMSMQDPIADMFTRIRNGLSAEKEVVSV-PFSKMKMEIANFLVNEGYIKGCS KGT-TL-A-G-------HPSIEIELKYH----AG-------A---PVIEMIKRVSRPSLRIYKSHEELPKVYGGFGVAII STSKGLVSDRKARDLGVGGEIIGYVAINNQRIRIRLKAFDHKLIDISTQEIVDTAKKTGAQVKGPIPLPVRKEKFTILIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMKLDLASGVDVQISLIRLLEGKVSSVAMDKTVVVRAERYVKHPLYG KFVKKTTKYYVHDEK--NECKEGDVIKFKETRPYSKTKKWCLVDIINRE------------------------------- -MPRSL-KKGPFVDH-HLLKKVFEAQE---SNSKK----PIKTWSRRSLIVPDMIGLTIAVHNGQQHVPVLMTE-EMVGH KLGEFAVTRNYRGHA------A---DK----KAK------KK >GAMMA_Francisella_tularensis_holarctica_FTA Concatenation of 2 sequences IEIKKAKPTSPGRRHVVSVKNTE-LHTG------------KP-FKGLVEVKKSKAGRNNTGRITVRH-QGGGHKQH---- YRIVDFK-R--NK-DDITAKVERIEYDPNRSANIALVLYA-DGERRYIVAPKGLKKDMSVISGE-K-VD-IAVGNCMPLR NIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGK--DNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGIPTKGYKTR-RNKRSNK---LIVQKR --------------------------------MSL---G-LVGRKCGMTRIFT-EDGV---------SIPVTVVQVEPNK VTQVK----TVE----K--DGY--NAIQVTT-------GF--KVNK----------PMAGHYK----------------- ---AS-VEPGRGLWEFTV--------DAAAEY-----QV---GS-SFDA--T-M-FEAGQKVDVRGVSKGKGFQGGVKRH NFAT-QDATHGNSLSHRV-HGSTGQN-QTPG-RVFKNKKMAGHLGNENVTIQSLEVVRVDAENG---------------- ----------LLLLKGG-IPGSVGGDIIVT--MDLNIKS-LAGQEA-GSLGVAEGVF----AA-DY-NEALIHQVVVAYM AGARQGTKAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IF---- RKGGVTFAAK-P-KSYKQKVNRKMYSGAVKSILSELLRSG----------------R-MTIVEEL----KLE-T------ --PKTRLFV--VGVEEFSE---NLYLSSRNLKNVA-V---------------CDSVEINPVSLVCFEN----VVLTKKAI KEIEARLKDYYQKEL----VAKLKTELGLDNIMEVPAIKKITLNMGVG-DAAKDKKIMTFALNDLTAIAGQKPVVTKSKK SIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSA-KSFDGRGNYSLGMREQISFPEID-----YDKV DSIRGLDISITTT-----------------------AKNDDQGRALLKAFGFPFMSRIG-K--KPVVIPSGVTIN-V--- -A-A-GN-KVEVKGAKATLSKTF--ST-D--VTFSVAD-NV--ATI----T-P--NNNKNAV-AQSGTARAILSNMVEGV SKGFERKLKIIGVGY--RAKAQG-NE--LNLT--LGFSHPVVYKL-P-Q-GITAETP--A-PTEIILKG-ADKELLGKVA SEVREYR------KPEPY---KGKGVRYEDEYVAKKEAK----------MIQMQTELQVADNSGAKRVECIKVLG-SHRR Y--ASIGDVIKVTVKEASPR-G-------KAKKGSVYNAVVVRTAKGVRRKDGSKVRFDGNAAVLLN-ANGQ-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NTLAPAAGS-KSAPKRLG-RGIGSGL-GKTSGKGHKGQKARSGGY-H--- -KVGF-E-GGQMPLQRRLPK-FG--FPSIRLHELVTLDTLKDF-GLIRVK---------VIA--SGE-I-Q-K-A-VSL- KGIACTKGAKEAIEKAGGKV-K---QQK--LRN---RGLA-YRGNKVSFG----------EFGLQAT--SRGRITARQIE AGRRAISRHI------KRGGKIWIRIFPDKPITQKPLEVRMGKGK---------GSVEYWVAQIQP-GRVLYEI--TG-- VKEELAREAFARAAAKMPVQTTF-VKKTARLSRSKRTRIKL----RELGHTRLCVYRTPRHVYAQVISG---D--GSTVL VAASTV-EKDV-KAKC----KYT-GNVESAAIVGEIIADR--CKEKG-ISQVAFDRSGYKYH--GRVKALVEAAREHGLQ F--------------------------------------------------------------ME-VQAKLKFARISAQK CRLVADQIRGLPVEQAINLLTFS---------------------------------NKKAAVLIKGVLNSAVAN----A- EHND-GMDVDSLVVSTIFVDEGPTMKRFEARAKGRGNRILKRTSHITVKVAEMNRLKKGDDVIVIAGK------DK-GRR GVVKSFAKGGS--LVL--VEGINIVKKHIK----PN--PNRGIE-GGVVEKELPVDASNVA-IFNPAT-------EK--A --DRVGYKF---VD--------EKKVR---YFKSNG---ELV--MGQKVNPNGIRLG--YI-RDWRSTWYA------DSS R--YATKLNEDIKVREFL--HKKLA-----AAAVSKIQIERPA-Q-NAKITIHTARPGIVIGKKGEDVEKLRAEVHKLVQ INIEEVRK---PEIDAKLVAESVAQQLEKRVMFRRAMKKAMQAAMKS-GAKGIKIMVSGRLGGAEIARSEWARDGRVPL- -QTFRADVDYATAEALTTYGVIGVKVWIY--MQDPIADMFTRIRNGLSAEKEFVSV-PFSKIKMEIANFLVNEGYIKSCS KGT----T-SMG-----HPSIEIELKYH----AG-------A---PVIEMIKRVSRPSLRIYKSHADLPKVYGGYGVAIV STSKGLVSDRKARDLGVGGEIIGYVAINNQRIRIRLKAFDHKLIDISTQEIVDTAKKTGAQVKGPIPLPVRKEKFTILIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMKLDLASGVDVQISLTRLLEGKVSSVAMDKTVVVRAERYVKHPLYG KFVKKTTKYYVHDEN--NECKEGDVIKFKETRPYSKTKKWCLVDIIHRE------------------------------- -MPRSL-KKGPFVDH-HLLKKVFEAQE---SNSKK----PIKTWSRRSMIVPDMIGLTIAVHNGQQHVPVLMTE-EMVGH KLGEFVVTRNYRGHA------A---DK----KAK------KK >GAMMA_Francisella_tularensis_tularensis_FSC_198 Concatenation of 2 sequences IEIKKAKPTSPGRRHVVSVKNTE-LHTG------------KP-FKGLVEVKKSKAGRNNTGRITVRH-QGGGHKQH---- YRIVDFK-R--NK-DDITAKVERIEYDPNRSANIALVLYA-DGERRYIVAPKGLKKDMSVISGE-K-VD-VAVGNCMPLR NIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGK--DNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGIPTKGYKTR-RNKR-SN-K-LIVQKR --------------------------------MSL---G-LVGRKCGMTRIFT-EDGV---------SIPVTVVQVEPNK VTQVK----TVE----K--DGY--NAIQVTT-------GF--KVNK----------PMAGHYK----------------- ---AS-VEPGRGLWEFTV--------DAAAEY-----QV---GS-SFDA--T-M-FEAGQKVDVRGVSKGKGFQGGVKRH NFAT-QDATHGNSLSHRV-HGSTGQN-QTPG-RVFKNKKMAGHLGNENVTIQSLEVVRVDAENG---------------- ----------LLLLKGG-IPGSVGGDIIVT--MDLNIKS-LAGQEA-GSLGVAEGVF----AA-DY-NEALIHQVVVAYM AGARQGTKAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IF---- RKGGVTFAAK-P-KSYKQKVNRKMYSGAVKSILSELLRSG----------------R-MTIVEEL----KLE-T------ --PKTRLFV--VGVEEFSE---NLYLSSRNLKNVA-V---------------CDSVEINPVSLVCFEN----VVLTKKAI KEIEARLKDYYQKEL----VAKLKTELGLDNIMEVPTIKKITLNMGVG-DAAKDKKIMTFALNDLTAIAGQKPVVTKSKK SIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSA-KSFDGRGNYSLGMREQISFPEID-----YDKV DSIRGLDISITTT-----------------------AKNDDQGRALLKAFGFPFMSRIG-K--KPVVIPSGVTIN-V--- -A-A-GN-KVEVKGAKATLSKTF--ST-D--VTFSVAD-NV--ATI----T-P--NNNKNAV-AQSGTARAILSNMVEGV SKGFERKLKIIGVGY--RAKAQG-NE--LNLT--LGFSHPVVYKL-P-Q-GITAETP--A-PTEIILKG-ADKELLGKVA SEIREYR------KPEPY---KGKGVRYEDEYVAKKEAK----------MIQMQTELQVADNSGAKRVECIKVLG-SHRR Y--ASIGDVIKVTVKEASPR-G-------KAKKGSVYNAVVVRTAKGVRRKDGSKVRFDGNAAVLLN-ANGQ-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NTLAPAAGS-KSAPKRLG-RGIGSGL-GKTSGKGHKGQKARSGGY-H--- -KVGF-E-GGQMPLQRRLPK-FG--FTSIRLHELVTLDTLKDF-GLIRVK---------VIA--SGE-I-Q-K-A-VSL- KGIACTKGAKEAIEKAGGKV-K---QQK--LRN---RGLA-HRGNKVSFG----------EFGLQAT--SRGRITARQIE AGRRAISRHI------KRGGKIWIRIFPDKPITQKPLEVRMGKGK---------GSVEYWVAQIQP-GRVLYEI--TG-- VKEELAREAFARAAAKMPVQTTF-VKKTARLSRSKRTRIKL----RELGHTRLCVYRTPRHVYAQVISG---D--GSTVL VAASTV-EKDV-KAKC----KYT-GNVESAAIVGEIIADR--CKEKG-ISQVAFDRSGYKYH--GRVKALVEAAREHGLQ F--------------------------------------------------------------ME-VQAKLKFARISAQK CRLVADQIRGLPVEQAINLLTFS---------------------------------NKKAAVLIKGVLNSAVAN----A- EHND-GMDVDSLVVSTIFVDEGPTMKRFEARAKGRGNRILKRTSHITVKVAEMNRLKKGDDVIVIAGK------DK-GRR GVVKSFAKGGS--LVL--VEGINIVKKHIK----PN-PNR-GIE-DGVVEKELPVDASNVA-IFNPAT-------EK--A --DRVGYKF---VD--------EKKVR---YFKSNG---ELV--MGQKVNPNGIRLG--YI-RDWRSTWYA------DSS R--YATKLNEDIKVREFL--HKKLA-----AAAVSKIQIERPA-Q-NAKITIHTARSGIVIGKKGEDVEKLRAEVHKLVQ INIEEVRK---PEIDAKLVAESVAQQLEKRVMFRRAMKKAMQAAMKS-GAKGIKIMVSGRLGGAEIARSEWARDGRVPL- -QTFRADVDYATAEALTTYGVIGVKVWIYMSMQDPIADMFTRIRNGLSAEKEFVSV-PFSKIKMEIANFLVNEGYIKSCS KGT-TSMG---------HPSIEVELKYH----AG-------A---PVIEMIKRVSRPSLRIYKSHADLPKVYGGYGVAIV STSKGLVSDRKARDLGVGGEIIGYVAINNQRIRIRLKAFDHKLIDISTQEIVDTAKKTGAQVKGPIPLPVRKERFTILIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMKLDLASGVDVQISLIRLLEGKVSSVAMDKTVVVRAERYVKHPLYG KFVKKTTKYYVHDEN--NECKEGDVIKFKETRPYSKTKKWCLVDIIHRE------------------------------- -MPRSL-KKGPFVDH-HLLKKVFEAQE---SNSKK----PIKTWSRRSMIVPDMIGLTIAVHNGQQHVPVLMTE-EMVGH KLGEFVVTRNYRGHA------A---DK----KAK------KK >GAMMA_Haemophilus_ducreyi_35000HP Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAE-LHKG------------KP-YAPLLDTKSKTGGRNNLGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-FDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSVGDMIQAGA-S-AP-IKVGNALPMR NIPVGTTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECIATIGEVGNSEHMLRVLGKAGAN -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFN-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--SAIQVTT-------GT--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT---------EGEEF-----TL---GQ-EINV--D-I-FADVKKVDVTGTSKGKGFAGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGA-VPGATNSNVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGTTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQE----------------R-LVVVEKF----EVE-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VVITTDAV KQIEAKLHDYYRDQV----VNELKTKFNYSSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAVFNFPFMSRVA-K--APVNIPAGIEVK-I--- -N-G--Q-LLTVKGKNGELSREI--HN-A--VEVNQDA-NA--LTF----V-P--REGANAD-AQAGTARALVNAMVIGV TEGFTKKLQLVGVGY--RAQMKG-NV--VALS--LGYSHPIEHTL-P-L-GVTGECP--S-QTEIILKS-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYSDEVVRTKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NSLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLNDLVTLEALKAA-NIITVK---------VIL--AGK-I-E-R-A-LVI- KGLRVTKGAKAAIEAVGGSI-K---VHK--GRN---RGIA--VGTEVSFG----------TFGLKAI--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEIARHAFALAAAKLPMKTTF-VKKVARIRRASRARHLM----REQGATRLVVHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKVI-KEQV----QYT-GNKDAAAIVGKLVAER--ALAKG-IQVVAFDRSGFKYH--GRVQVLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAQALEILTFT---------------------------------NKKASALVKKVLESAIAN----A- EHND-GADVDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLAGK------DK-NKR GKVTKVLPNGK---VI--VEGINLITKHEK----PV--PALGKA-GGLVKKEAAIDVSNVA-IFNPTT-------NK--A --DRVGFRF----E--------DNKVR---FFKSNN---EII--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTQ D--FADNLDGDFKVRKFL--NKELA-----NASVSRIIIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVSQIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIANVLAKEGYVESFR IIE----D--------SKPELEITLKYF---QNK-----------PVVESIQRISRPGIRIYKRKDELPKVMGGLGIAIV STSKGVMTDRAAREEGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRAGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGKVVSDKMDKSFVVAIERTVKHPLYG KFIRRTTKLHVHDEN--NEAKLGDVVEIQECRPVSKTKSHKLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Haemophilus_influenzae_PittEE Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLDTKSKTGGRNNYGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSVGDQIQAGI-N-SP-IKVGNSLPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECVATIGEVGNSEHMLRVLGKAGAN -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGTRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------AGD---IK-SP----IW---- RSGGTTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVEKF----ELD-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VIVTVDAV KQIEAKLHDYYRDQV----VSELKNKFGYKSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLAAISGQKPLVTKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKNDEEGQALLAAFNFPFMSRVA-K--APVNIPAGVEVK-L--- -D-G--Q-LLTVKGKNGELSRKI--HE-S--VEVKQDN-GQ--FTF----T-P--REGVEAN-AQSGTARALVNAMVIGV TEGFTKKLVLVGVGY--RAQLKG-NA--IALS--LGYSHPVEHTL-P-V-GITAECP--S-QTEIVLKG-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYADEVVRIKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKITVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLNELVTLETLKAA-NILTAK---------VIL--AGE-V-K-S-A-VTV- RGLRVTKGAKAAIEAAGGSI-K---VHK--GRN---RGIA--SGTEVSFG----------TYGLKAV--GRCRLTARQIE AARRAMSRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEVARNAFALAAAKLPVKTTF-VKKSARIRRAARARHMM----REQGVTRLVIHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKAI-REQV----KYT-GNKDAAAAVGKAVAER--ALAKG-VQAVAFDRSGFKYH--GRVQTLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAQALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLTGK------DK-GKR GKVTKVLPNGK---VF--VEGINIITKHEK----PV--PALGKA-GGLVKKEAAIEASNVA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EII--MGQKVHPHGIRLG--IV-KPWSSTWFA------NTQ D--FADNLEGDFKVRKFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVSKIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQSAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAINM-PSSKLKVAIANVLAAEGYIESVK VLE--------G----AKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRSVQGKVVSDKMEKSFVVAIERKVKHPLYG KFIRRTTKLHVHDEN--NEAKVGDTVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Haemophilus_influenzae_Rd_KW20 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLDTKSKTGGRNNYGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSVGDQIQAGI-N-SP-IKVGNSLPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECVATIGEVGNSEHMLRVLGKAGAN -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRIFN-EDGV---------SVPVTVIEIEANR VTQVK----TLE----N--DGY--TAVQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT---------EGEEF-----TL---GQ-EINV--D-I-FADVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGS-VPGAINGDVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGTRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------AGD---IK-SP----IW---- RSGGTTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVEKF----ELD-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VIVTVDAV KQIE----------------------------------------MGVG-EALTDKKLLDNAVADLAAISGQKPLVTKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKNDEEGQALLAAFNFPFMSRVA-K--APVNIPAGVEVK-L--- -D-G--Q-LLTVKGKNGELSRKI--HE-S--VEVKQDN-GQ--FTF----T-P--REGVEAN-AQSGTARALVNAMVIGV TEGFTKKLVLVGVGY--RAQLKG-NA--IALS--LGYSHPVEHTL-P-V-GITAECP--S-QTEIVLKG-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYADEVVRIKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKITVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLNELVTLETLKAA-NILTAK---------VIL--AGE-V-K-S-A-VTV- RGLRVTKGAKAAIEAAGGSI-K---VHK--GRN---RGIA--SGTEVSFG----------TYGLKAV--GRCRLTARQIE AARRAMSRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEVARNAFALAAAKLPVKTTF-VKKSARIRRAARARHMM----REQGVTRLVIHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKAI-REQV----KYT-GNKDAAAAVGKAVAER--ALAKG-VQAVAFDRSGFKYH--GRVQTLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAQALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDPAKIRQNDEVIVLTGK------DK-GKR GKVTKVLPNGK---VF--VEGINIITKHEK----PV--PALGKA-GGLVKKEAAIDASNVA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EII--MGQKVHPHGIRLG--IV-KPWSSTWFA------NTQ D--FADNLEGDFKVRKFL--NKELA-----SASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVSKIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQSAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAINM-PSSKLKVAIANVLAAEGYIESVK VLE--------G----AKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRSVQGKVVSDKMEKSFVVAIERKVKHPLYG KFIRRTTKLHVHDEN--NEAKVGDTVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Haemophilus_parasuis_SH0165 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNTE-LHKG------------KP-FAALLDTKSKTGGRNNLGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLVAGDTIQAGA-S-AP-IKVGNSLPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECSATIGEVGNSEHMLRVLGKAGAN -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGRKVGMTRIFN-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--TAVQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRTE---------GEEF-----TL---GQ-EINV--D-I-FTDVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGS-VPGATNSDVIVK--MELQVVG-A------TALSVSETTF----GR-EF-NEALIHQVVVAYA AGARQGTRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVDKF----EID-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VVITVDAV KQIEAKLHDYYRDTV----VNELKAKFNYSSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLNA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKTDEEGQALLAAFNFPFMSRVA-K--APVAVPAGVQVT-L--- -N-G--Q-LLTVKGKNGELSREI--HN-A--VEVKYEA-DT--LTF----A-P--KAGVNAD-AQAGTARALVNAMVIGV TEGFTKKLQLVGVGY--RAQMKG-NT--VALN--LGFSHSVEHEL-P-A-GVTGECP--S-QTEIILKS-ADKQLIGQVA ADIRAYR------KPEPY---KGKGVRYADEVVRIKEAK-----------------------------MCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGAVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NSLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVTLDALKAA-NVITAK---------VIL--SGK-V-E-K-A-VVV- KGLGVTKGAKAAIEAAGGSI-K---VHK--GRN---RGIA--GGTEVSFG----------SFGLKAI--GRGRLTARQIE AARRAMSRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEVARNAFALAAAKLPFKTTF-VKKVARIRRASRARHLM----REQGATRLVVHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKVI-KEQV----KYT-GNKEAAAVVGKIVAER--ALEKG-IKAVAFDRSGFKYH--GRVQSLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVSAALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADVDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLAGK------DK-GKR GKVTKVLPNGK---VV--VEGINIITKHEK----PV--PALGKA-GGLVKKEAAIDASNVA-IFNPET-------NK--A --DRVGFRF----E--------DGKVR---FFKSNE---KTI--MGQKVHPHGIRLG--IV-KPWSSTWFA------NTQ D--FADNLEGDFKVRQFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVSKIAQ INISEVKK---PELDAKLVADSIAAQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIASVLAEEGYVESFK VVE--------G----SKPELEITLKYF---QNK-----------PVVESIQRVSRPGLRIYKRKDELPKVMGGLGIAVV STSKGVMTDRAARQASLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGKVVSDKMDKSFVVAIERTVKHPIYG KFIRRTTKLHVHDEN--NEAKLGDVVEVKECRPLSKTKSHTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Haemophilus_somnus_129PT Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLGIKSKTGGRNNLGRITTRH-IGGGHKQH---- YRVIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSAGDQIQSGI-N-AP-IKIGNSLPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLSECVATIGEVGNSEHMLRVLGKAGAN -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRIFN-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--TAVQVTT-------GF--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT---------EGEEF-----TL---GQ-EINV--D-I-FTDVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEIVRVDVERK---------------- ----------LLLVKGS-VPGATNSDVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVEKF----EID-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQAIDPVSLIAFDK----VVVTVDAV KQIEAKLHDYYRDTV----VNELKAKFNYSSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLAAISGQKPLVTKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLNT-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAAFNFPFMSRVA-K--APVSIPASVEVK-L--- -D-G--Q-LLTVKGKNGELSRTI--HN-S--VEVKQDN-NQ--LTF----S-P--RVGANAD-AQSGTARALVNAMVIGV NEGFTKKLQLVGVGY--RAQMKG-NV--LVLS--LGFSHPIDHVL-P-A-GVTAECP--S-QTEIVLKS-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYADEVVRMKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGAVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHNAKRLG-RGIGSGL-GKTSGRGHKGQKARTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLNDLITLDTLKAA-NVLTAK---------VIL--AGE-V-K-T-A-VTI- RGLGVTKGAKVAIEAAGGSI-K---VHK--GRN---RGIA--AGTEVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVMYEM--DG-- VSEEVARHAFALAAAKLPIKTTF-VKKSARIRRAARARHMM----REQGVIRLVIHRTSRHIYAQVIAP---N--GSEVL ATASTV-EKAI-SEQV----KYT-GNKDAAAVVGKIVAER--ALEKG-IKSVAFDRSGFKYH--GRVQSLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLVRGKKVAQALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLAGK------DK-GKR GKVTKVLPNGK---VF--VEGVNIITKHEK----PV--PALGKA-GGLVKKEAAIDVSNVA-IFNPTT-------NK--A --DRVGFRI----E--------DGKVR---FFKSNN---EII--MGQKVHPHGIRLG--IV-KPWNSTWFA------NTQ D--FADNLDGDFKVRQFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVAAIAQ INIAEVKK---PELDAKLVAGSIASQLERRVMFRRAMKKAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIANVLAEEGYIANVK VSE--------G----VKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKNELPKVMGGLGVAVV STSKGIMTDRKARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGKVISDKMDKSFVVAIERTVKHPIYG KFIRRTTKLHVHDEH--NEAKLGDVVEVRGCRPLSKTKSHTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Haemophilus_somnus_2336 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLGTKSKTGGRNNLGRITTRH-IGGGHKQH---- YRVIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSAGDQIQSGI-N-AP-IKIGNSLPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLSECVATIGEVGNSEHMLRVLGKAGAN -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRIFN-EDGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--TAVQVTT-------GF--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRTE---------GEEF-----TL---GQ-EINV--D-I-FTDVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEIVRVDVERK---------------- ----------LLLVKGS-VPGATNSDVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVEKF----EID-V------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQAIDPVSLIAFDK----VVVTVDAV KQIEAKLHDYYRDTV----VNELKAKFNYSSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLAAISGQKPLVTKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLNT-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAAFNFPFMSRVA-K--APVSIPAGVEVK-L--- -D-G--Q-LLTVKGKNGELSHTI--HN-S--VEVKQDN-NQ--LTF----S-P--RVGANAD-AQSGTARALVNAMVIGV NEGFTKKLQLVGVGY--RAQMKG-NV--LVLS--LGFSHPIDHVL-P-A-GVTAECP--S-QTEIVLKS-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYADEVVRMKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGAVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHNAKRLG-RGIGSGL-GKTSGRGHKGQKARTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLNDLITLDTLKAA-NVLTAK---------VIL--AGE-V-K-T-A-VTI- RGLGVTKGAKVAIEAAGGSI-K---VHK--GRN---RGIA--AGTEVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVMYEM--DG-- VSEEVARHAFALAAAKLPIKTTF-VKKSARIRRAARARHMM----REQGVIRLVIHRTSRHIYAQVIAP---N--GSEVL ATASTV-EKAI-SEQV----KYT-GNKDAAAVVGKIVAER--ALEKG-IKSVAFDRSGFKYH--GRVQSLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSVQK ARLVADLVRGKKVAQALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLAGK------DK-GKR GKVTKVLPNGK---VF--VEGVNIITKHEK----PV--PALGKA-GGLVKKEAAIDVSNVA-IFNPTT-------NK--A --DRVGFRI----E--------DGKVR---FFKSNN---EII--MGQKVHPHGIRLG--IV-KPWNSTWFA------NTQ D--FADNLDGDFKVRQFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVAAIAQ INIAEVKK---PELDAKLVAGSIASQLERRVMFRRAMKKAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIANVLAEEGYIANVK VSE--------G----VKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKNELPKVMGGLGVAVV STSKGIMTDRKARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGKVISDKMDKSFVVAIERTVKHPIYG KFIRRTTKLHVHDEH--NEAKLGDVVEVRGCRPLSKTKSHTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Hahella_chejuensis_KCTC_2396 Concatenation of 2 sequences MPVVKTKPTSPGRRHVVAVTNPS-LHKG------------AP-LASLTEKKRKNGGRNNAGRITVRH-QGGGHKQL---- YRVIDFK-R--TK-DGIPAVVERLEYDPNRTAHIALLKYA-DGERRYIIAPKGVSVGDAIASGQ-E-AP-IRVGSCLPLR NIPVGSVVHCIEMKPGKGAQIARSAGASAQVVAR--EGAYATIRLRSGEMRKVLVECRATLGEVSNSENNLRVYGKAGAK -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVPTKGYKTR-KNKR-TD-K-MIVRRR --------------------------------MAI---G-LVGRKAGMTRLFE-DDGA---------AVPVTVIQVEKNV IAQVK----SLE----V--DGY--RAIQVTS-------GS--VVNK----------PMAGHFK----------------- ---AG-VEAGRVVCEFTL------DATDSAEY-----KV---GD-EVSV--T-I-FEAGQKVDVSGRSKGKGFAGVIKRW NFST-QDATHGNSLSHRA-PGSIGQN-QSPG-RVFKGKKMAGQMGNKNVTVQTLKVVRVDEEKG---------------- ----------LLLIKGA-VPGATGADVVIK--MELT----INGAGK-GTVSVSDVAF----AR-DF-NEALVHQVVTAYL AGGRQGSKAQKTRSQ--------VS-GGGKKPW---------RQKGSGRAR--------AGT---IR-SP----IW---- RGGGKTFAAT-P-LDHSQKVNKKMYRAAMQSILSELVRQE----------------R-LVVVEEM----AVE-A------ --PKTKLIV--ADAVD--Q---NLYLASRNIPHVD-V---------------CDAVAINPVSLIAHDK----VLVTVSAL KKIEPKYKEVYQKEV----IPALMKEMSYSSVMQVPRIEKITLNMGVG-EALGDKKQIEAAAADLEAITGQKVVVTKARK SVAGFKIRQGFPIGCKVTLRGDRMWEFFERLVDVAIPRVRDFRGLNQ-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DKVRGMDITITTS-----------------------ANTDDEGRALLNAFSFPFMSRVA-K--NPVQIPAGVEVK-F--- -D-G--R-LVNIKGGKGALSLSV--HP-S--VEVKQED-GA--LTF----G-P--KEGNQAR-ALAGTTRALINNMVLGV TQGFERKLELIGVGY--RAQAQG-KA--INLT--LGFSHPVVFEI-P-E-GITAETP--T-QTEIVIRG-IDKQKVGQVA AEIRSIR------PPEPY---KGKGVRYSGEQVRVKEAK----------MIQTQTVLDVADNSGARRVMCIKVLG-SHRR Y--ASIGDVIKVSVKEAIPR-G-------KVKKGQVLKAVVVRTRKGVRRQDGSLIRFDGNAAVLLN-NQEQ-PIGTRIF GPVTRELR-GEKFMKIISLAPEVLMK-M--NTLKPAEGS-KQSPKRLG-RGIGSGL-GKTGGRGHKGQTSRSGGT-I--- -RPGF-E-GGQQPLQRRLPK-FG--FTSVRLSEIIDLAALKAA-NIVDVK---------VIL--SGE-I-T-R-A-VTV- KGLKVTKGAQEAIQAAGGKV-K---VHK--GRN---TGLA-QRGNKVSFG----------EFGLKAT--GRGRITARQIE AARRTMTRRI------KRGGKIWIRIFPDKPITKKPLEVRMGKGK---------GPVEYWVAEIEP-GRMLYEM--EG-- VSEELAREAFTLAAAKLPVATTF-VKKISRLRRAKKTRYKI----RELGVDRLSINRTPRHIYAQIISA---D--GSKVL ATASTL-DKDL-RA------GAT-GNVEAAGKVGAMIAER--AKAAG-ITKVAFDRSGFKYH--GRVKALADAARENGLE F--------------------------------------------------------------ME-VAAKLFGARLSAQK ARLVADQVRGKRVEEALDILTFS---------------------------------PKKASSIIKKVLESAIAN----A- EHNE-GLDVDELKVATICVDEGPTMKRIKPRAKGRADRIFKRTCHITVKVAEMNKIRKGDEVVVIAGR------DK-GKR GKVNRVQKD-G--KLV--VSGVNMVKRHTK----PN--PMLGTA-GGIVEKEAPIQASNVA-IFNSAT-------DK--P --DRIGFKI---LE--------DGKVR---IFKSTN---ELV--MGQKVNPVGIRLG--IV-KDHNSVWYA------DKK N--YSDHLLTDIKVREFL--MKKLE-----KASVSKVIIERPP-Q-NAKITIHTARPGIVIGKKGEDVDRLRQEVGELVH INIEEIRK---PDLDAKLVASGVAGQLERRVMFRRAMKRAVQNAMRQ-GAKGIKIQVGGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATHEAHTTYGVIGVKVWIFMSMQDTLADMFTRIRNAQMAEKETVRM-PSSKMKVAVANVLKEEGFITDYK ASE----E--------AKPVLEITLKYY----QG-------A---PVIENISRASRPGLRQYKAANDLPTVNGGLGIAIV STSKGVMTDRAARKAGVGGEVICTVFMQGQKIRIRLKAFDYRLIDQSTQEIVDTAKRTGAQVRGPIPLPTKKERFTVLIS PHVNKDAR-DQYEIRTHKRLLDIVEPTEKTVDALMKLDLAAGVDVQISLVRTETGKVVSDKMDKSIVVLVERRVKHPLYG KYVKRSSKLHAHDEN--NECRIGDTVQVQESRPLSKTKSWKLVNIVERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVETAVE---VKDKK----PIKTWSRRSTIFPEMVGLTIAVHNGRQHVPVYVTE-DMVGH KLGEFAATRTYRGHA------A---DK----KAK------R- >GAMMA_Halorhodospira_halophila_SL1 Concatenation of 2 sequences MALVKSKPTSPGRRFVVKTKDAR-LHQG------------GP-YEPLVVQKSKTGGRNSNGRITTRH-RGGGHKQR---- YRQIDFK-R--NK-TGVPGKVERLEYDPNRSANIALVLYQ-DGERRYIIAPRGVEPGSPIQSGR-D-AA-IKPGNALPLR NIPVGTQVHCVELKPGKGAQLARSAGAGVQVVAR--ESGMATLRLRSGEMRRVPADCMATVGEVGNAEHSLRNLGKAGAK -RHL-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----AGGRHPVSP---WGMPTKGHKTR-KNKR-TD-K-YIVRRR --------------------------------MAI---G-IVGRKRGMTRVFT-EEGG---------SIPVTVVEADPNR VTQVK----TEE----S--DGY--RAVQVTA-------GR--RVRK----------PEAGHFR----------------- ---AG-VEAGRGVWEFRL---DKGQRASDEEMP----ET---GG-SIDV--G-G-FEAGQKVDVTGTTKGRGFAGTVRRH NFRA-QRNTHGNSKSHRV-PGSIGQC-QSPG-RVFKGKKMAGQMGNRRATIQNLEVVRVDSERN---------------- ----------LLLIRGA-VPGAVGSDLIVR--MELKLSN-EKGEAA-GQLEVSDQAF----DA-PF-RESLVHQVVTAHL AGARAGTKAQKTRSE--------VA-GGGKKPW---------RQKGTGNAR--------AGT---IR-SP----LW---- RGGGQTFAAK-P-RDFSQKVNRKMYRGALRSILSELARQD----------------R-LVVVKQL----TVD-A------ --PKTRLIV--VDEID--A---NLELAARNLPRLG-V---------------VDAAGVDPASLVGAER----VVITESAI RRVEATLRKVYREEV----TPALKERFGYQNVMQVPQLQKIVINMGLG-EATKDKKILEAAQEDLAKIAGQKPVVTRARK SVAGFKIREGWPIGCKVTLRRDRMYEFLERFIHVASPRVRDFRGFSP-RSFDGRGNYNLGIREQLIFPEID-----YDEI DRVRGMDITVSTT-----------------------ARTDAEGKALLEGFGFPFMSRVA-K--APVEVPSGVEVT-L--- -Q-G--N-DIQVKGPKGQMAWSC--HR-L--VSLNQEE-GT--LTF----E-P--RQQTRAV-ALTGTTRALVQNMVTGV SEGFERRLELKGVGY--RAQVQG-ST--LNLT--LGFSHPVHYEI-P-E-GVTIECP--S-QTEVVVKG-ADKQQVGQVA AQIRGYR------PPEPY---KGKGVRYADERVVLKEAK----------MIQMESLLKAADNSGARQVQCIKVLG-SKRR Y--AGIGDIVKVSVKDAIPR-G-------RVKKGEVYNAVVVRSKRGVRRADGSQIRFDGNAAVLLN-NNLQ-PIGTRVF GPVTRELR-NERFMRIISLAPEVLMR-L--NQLSPSAGS-RPDAKRAG-RGAGSGL-GKTAGRGHKGQHSRSGGF-H--- -KVGF-E-GGQMPLQRRVPK-YG--FSSVRLHEIVDLAALHKA-GVVRVK---------VIA--SGT-I-D-R-A-VSV- RGVKVTQGARKAIEAAGGQV-K---KQK--GRC---SGLA-TRGDRVSFG----------EFGLKAT--TRGPITSRQIE AARRAINRYI------RRGGKIWIRVFPDKPVTEKPLEVRMGKGK---------GNVDHWCEPIAP-GRVLYEL--EG-- VSEEVAREAFRRAAAKLPVKTTF-VKKTARMRRARKSRGRI----RDVGAYRLSVHRTPRHIYAQVQQP---D--GATTL AAASTV-EPAL-RQRS----EGT-GNVSAAQEVGRLIAER--AKAAG-IEQVAFDRGGYQYH--GRVQALAEAAREAGLK F--------------------------------------------------------------ME-TQAKLRFSRVSPQK ARLVADQIRGLPVDDALRTLEYS---------------------------------PRKAAEIVRKVLESAVAN----A- EHND-GADVDELRVARIFVDEGPTMKRIQPRAKGRANRILKRTSHITVAVAEMRKIRTGDEVIVIAGK------DK-GRR GRVSRVIPEKD--RVI--VDNVNMVKRHTR----GN--PMQGTT-GGIIEKEAPIHISNVA-IYNPET-------EK--A --DRVGVRQ-------------EGKVR---YFKSNQ---QLI--MGNKTHPTGFRLG--VT-EDWRSMWYA------DSS N--FGKYLNTDLEVREFI--RERLK-----NASVSRIQIERPA-K-NALVTIHTARPGIVIGKKGEDIDRLRGEVAARVH INIEEIRK---PEADSKLVAESIAGQLERRVMFRRALKRAVGNAQRV-GAQGIKVQVSGRLNGSEIARTEWYREGRVPL- -HTLRADIDYGFAEAKTTYGVIGVKVWIFMSMTDPIADMLTRVRNAHHAEKADVRM-PSSKLKRAIAAVLQEEGYIEGYR EVG----E---E----KKPVLEVTLRYH----EG-------Q---PAIREIQRYSRPGLRVYRGRDELPRVRNGLGTAII STSKGVMSDGQARAQGHGGEVLCWVFTQNQRIRIRLKAFDHRLIDQSAREIVDTAKRTGAHVCGPIPLPVKKERFTVLTS PHVNKDAR-DQYEIRTHKRLMDIIDPTDKTVDALMKLDLAAGVDVQIKLTRTVNGRVVSSKMDKTLTVLVERRVKHPLYG KFIRRSTKLHAHDEG--NEGREGDWVSIQECRPLSKNKTWRLVKVLERA------------------------------- -MPRST-KKGPFIDH-HLLKKVEEANA---NNSKR----PIKTWSRRSVVMPDMVGLTIAIHNGRQHVPVLINE-NMVGH KLGEFAVTRSFRGHA------A---DK----KSK------R- >GAMMA_Idiomarina_loihiensis_L2TR Concatenation of 2 sequences MAVVKSKPTSPGQRHVVKVVGQD-LYKG------------KP-YAPLLEKNSKSGGRNNNGRITVRH-IGGGHKHH---- YRVIDFK-R--NK-DGIPAKVERIEYDPNRSANIALVLYA-DGERRYILAPKNLSVGDRIQSGV-D-AP-IKPGNSLPMR NIPVGSVVHAVELQPGKGAQMARSAGAYCQILAR--DGAYVTVRLRSGEMRRVQSEGRATIGEVGNAEHMLRQLGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGTPTKGYKTR-KNKR-TD-K-FIVRRR --------------------------------MAI---G-LVGRKVGMTRVFQ-EDGA---------SVPVTVIEVLANR VTQVK----SDD----T--DGY--RALQVTT-------GE--KVTK----------PLAGHFK----------------- ---AG-TEAGRGLWEFRL------QNGEGEDY-----AV---GS-ELTV--D-I-FAEVNKVDVTGTSKGKGFAGTVKRW NFSM-QDATHGNSLSHRA-PGSIGQN-QSPG-KVFKGKKMAGQMGNEQVTTQSLELVRVDAERS---------------- ----------LLLIKGA-VPGATGSDVIVK--MELTLKD-AK-----GALEVSEATF----GR-EF-NEALVHQVVVAYA AGARQGTKAQKTRSE--------VA-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RSGGATFAAK-P-QNHSQKVNKKMYRGAIKSILSELIRQE----------------R-LIVVEKF----GVD-E------ --PKTKLIV--TKEVD--E---NLFLASRNLHKVD-V---------------RDVQGIDPVSLIAFEK----VLMTADAV KQLEAKLHDFYRESV----VPELMKEFSYNSVMQVPRIDKITLNMGVG-EALADKKVLDNAVADLEAISGQKPIRTVARK SVAGFKVREGFPIGCKVTLRGERMWDFLQRLISIAIPRIRDFRGLNP-KSFDGRGNYSMGVREQIIFPEVD-----YDKV DKVRGLDITITTN-----------------------AGTDDEARALLAAFNFPFMSRVA-K--APIEIPAGVEVT-L--- -N-G--Q-EVTIKGAQGSLSRVV--ND-A--VELVKDE-SE--LRT----N-A--REGANST-AQAGTARALLQNMVVGV TKGFERKLQLIGVGY--RAQAQG-KK--LNLT--LGFSHPVEFEI-P-E-GITIDTP--T-QTEVVVKG-ADKQLVGQVA ANIRAYR------KPEPY---KGKGVRYADEQVRRKEAK----------MIQMQTTLDVADNSGARSVQCIKVLG-SHRR Y--ANIGDIIKVTVKEAIPR-G-------KVKKGDVVNAVVVRTRKGVRRQDGSVIRFDRNAAVLLN-NNQQ-PIGTRIF GPVTRELR-SEQFMKIISLAPEVLME-L--NTLAPAPGA-KSSKKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGS-V--- -KPGF-E-GGQMPIQRRLPK-FG--FTSVNLAEIVELATLKAA-GLVRAK---------VIK--SGE-L-S-R-A-VTV- KGLKVTKGAREAIEAAGGKI-K---VHT--GRN---RGLA-QSGNKVSFG----------TFGLKAT--DRGRMTARQIE AGRRAMTRHV------KRQGKIWIRVFPDKPITKKPLEVRMGKGK---------GNVEYWVAQIQP-GRVLYEM--DG-- VPEELAREAFRLAARKLPFKTTF-VNKAARLRRATRARKQI----KELGANRLVVHRTPRHIYAQLIAP---N--GSEVL AAASTA-EKSV-REGL----KST-GNVDAAKVVGKTIAER--AIEKG-VKNVSFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-AIAKHQFARVSAQK GRLVADQIRGLPVEKALDILAYS---------------------------------PKAAAGLIKKVLESAIAN----A- EHNE-GADIDELKVSRVFLDEGPTMKRIKPRAKGRADRIFKRTSHITVVVSDAAKIKRDDEVVVLAGK------DK-GKQ GKVLKVLTDKD--RVI--VEGVNVVKKHQK----PN--PALGES-GGIVEQEAAIHISNVA-ILNPET-------GK--A --DRVGFRL----E--------DGKVR---FFKSNN---AII--MGQKVHPNGIRLG--IS-RPWNATWYA------NTN E--FADNLHSDFQVRKFL--NKELR-----NASVSRIVIDRPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRKQVSKLAQ INISEVRK---PELDSQLVADNIAGQLERRVMFRRAMKRAVQNAIRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYSTSEANTTYGIIGVKVWIFMSMQDPIADMFTRIRNAQGANKVTVKM-PSSKQKVAIAQVLKEEGFITGYS AES----T--------VKPELEVELKYF----EG-------K---PVIETIERVSRPGLRIYKKRNELPNVMGGLGIAVV STSKGLMTDRAARQAGLGGEIIGYVAMANQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLIDIMDPTDKTVDALMRLDLAAGVDVQISLVRTLQGKVVSDKMDKTITVAVERRVKHPVYG KYITRTTKVHAHDEE--NQVKAGDTVIVRECRPLSKNKSWTLEEIVDRA------------------------------- -MPRSL-KKGPFIDL-HLLNKVEKALE---AGEKK----PIKTWSRRSMIIPDMIGLTIAVHNGRQHVPVYVTD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Klebsiella_pneumoniae_342 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVSP---WGLQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ADGEEF-----TV---GQ-NISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------IT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDANGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VAKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-V--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGVDGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-DV--VNLA--LGFSHPVEHKL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------------------------------------- -------------------------------------------------------------------------------- ------------------------MR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVDLNALKAA-NIIGAK---------VIL--SGE-V-T-R-P-VTV- RGLRVTKGARAAIEAAGGKI-K---VHK--GRN---RGLA--QGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFGLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-SEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TLAQHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQISNLA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------IKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISL------------------------------- -------------------------------------------------------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Klebsiella_pneumoniae_pneumoniae_MGH_78578 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVSP---WGLQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ADGEEF-----TV---GQ-NISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------IT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDANGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-TEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVDLNALKAA-NIIGAK---------VIL--SGE-V-T-R-P-VTV- RGLRVTKGARAAIEAAGGKI-K---VHK--GRN---RGLA--QGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFGLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TLAQHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKKKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERMVKHPVYG KFIKRTTKLHVHDEN--NECGIGDKVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Legionella_pneumophila_Lens Concatenation of 2 sequences MALLKSKPTSPGKRGEIRVVHHH-IYKG------------KP-HAALVEKLKKTGGRNNQGRITVRH-IGGGQRQK---- YRIIDFK-R--NK-DGILGRVERLEYDPNRTALIALISYK-DGEKRYIIAPSNLEVGATIQSGA-D-SP-ISVGNCLPLK NIPVGTTIHCVEMKPGKGAQMLRSAGCSGQLVAK--EGVYATLRLRSGEMRKIHVLCRAVIGEVSNSEHNLRALGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGLPTKGYKTR-SNKRTDT---FIVRGR --------------------------------MMI---G-LLGRKIGMTRVFT-PEGV---------SVPVSVVEVHPNR VSQVK----TAA----N--DGY--SAVQLTG-------GI--KVSK----------PVAGHFK----------------- ---AQ-IDAGDMQVEFRI--------DSEDAF-----TP---GQ-VISV-AD-V-FTAGQYVDVSGLTKGKGFAGTVKRH NFRT-QDASHGNSRSHRV-PGSIGQN-QTPG-RVFKGKKMAGHMGNARCTIQSLELVKVDSERN---------------- ----------LLLIKGA-IPGAPGSRVEIK--MEITTID-TK-----SKLKLNKEIF----AY-TY-NEGLVHQAVVTFM NNARSGNSAQKTRSE--------VS-GGGKKPW---------NQKGTGRAR--------AGT---IR-SP----LW---- RSGGVTFASK-K-RDYSQKLNKKMYKRALRSIISELCRTG----------------N-LVVVSDF----QCD-N------ --HKTKLII--MSEVG--E---NEYLGSRNLIDYD-I---------------CDVTTIDPVSLLRFEK----VVVTEAAI KKIEARLKEFYKKDV----VTMMMKRFNYSSVMEVPRILKITLNMGVG-EAVGDKKVMNHAIEDMTLISGQKPVVTKARK SIAGFKIREGWPIGCKVTLRRERMYEFLDRLISITLPRVRDFRGLNP-KSFDGTGNYSMGIHEQIVFPEID-----YDKT DGIRGLDICITTS-----------------------AKTNEEAKALLEAFNLPLMSRVA-K--APVIHSANVEVTFV--- -D-G----VITVKGPKGILTQKI--NK-LVNIQHSKES-NK--LEF----S-P-ASNDPMGW-AQAGTARALVRNMVQGV TEGYTVTLELVGVGY--RAQSKD-KS--ISLS--LGYSHSIEYDL-P-K-GVTVETP--N-NTTILLKG-VDKQVLGQIA SEIRAFR------PPEPY---KGKGVKYAGEQIVRKEAK----------MIQMQTVLEVADNSGARKVMCIKVLG-SHRR Y--ARVGDVIKVSVKDAIPR-S-------KVKKGAVMRAVVVRTAQGVRRDDGSLIRFDDNAAVLLN-NQNE-PIGTRIF GPVTRELR--ERFMKIISLAAEVLMN-L--NTLSPDPGS-RPSRRRVG-RGIGSGL-GKTCGKGHKGQKSRAGGY-H--- -KINF-E-GGQMPIQRRLPK-MG--FKSVSLGELIDLVALRKA-GLINVK---------VIL--SGE-L-T-A-A-IKL- KGLRVTKGARSAIESLGGSI-K---QMK--GRN---RGLA-LRGSKISFG----------EFGLKAV--ERGRLTARQIE AARRAMTRHI------KRGGKIWIRVFPDKPITQKPLEVRQGKGK---------GSVEYWVAQIQP-GKVLFEM--EG-- VSKELAMEAFDLAKAKLPFKVMF-EKQNARHRRGLKAKALI----RKTGRSRLVVYRSGVHIYSQIVKS---DQLGDKVL VASSTI-DKEL-RSSL----TGK-SKVEQASLVGQLLGKR--AKAAG-ITQVAFDRAGYKYH--GRVKALAEGAREAGLD F--------------------------------------------------------------ME-VTAKLKGAPLSAQK GRLVADMIRNMNVSGALDVLKFT---------------------------------PKKGAKLMLKLLESAIAN----A- ENNN-GADIDDLKVGMVCVDEATTLKRISPRAKGRANRICKRTCHITIKVSDMKRIKSGDEVIVIAGK------SK-GHI GKVLRVIDDA----VV--VEGGNLIKKHIK----PN--PQ-KPEKGGIIAREAPLHVSNVA-HYNPVT-------KK--A --DKVGFKY---LE-------SNGKVR---YYKSNN---EII--MGQKVNPIGIRLG--II-KDWNSKWFA------G-K R--YAEFLIQDIKLRSDL--KKKLM-----AAAVSKILIERPA-N-NAVVTILTARPGVIIGKKGGGIETLRKEISDSVH LNIEEVKK---PELDATLVAEGIAQQLEQRVMFRRAMKRAVTSALKA-GAKGIKICVSGRLGGAEIARSEWYREGRVPL- -HTFRADIDYGTAESKTTYGIIGVKVWIFMSMHDPIADMLTRIRNGQQAKHQQVTL-VSSKLKEEIARVLKEEGYIQDFF IET--LPN--------GLKSITLKLKYY----HG-------R---PVIEFIKRISRPGLRVYKSYKDLHSI-PGFGVAIL STSKGIMTHVSAKVKGVGGEVICEVASSNQNIKIRLKSFDHRLIDLSTREIVDTAKRTGAQIRGPIPLPIRKEKFTVLTS PHVNKDAR-DQYELRTHKRLVVIVHPTEKTVDALMKLDLAAGVDVQISLARTMIGKVVSDKMDKTIVVMIERTVKHPKYG KIMKRRTKLHAHDEN--QVCRVGNTVKIRESRPLSKTKSWVLVEVIS--------------------------------- -MARSI-RKGPFIDH-HLISKVEAAIE---SKSKK----PIKTWSRRSTIVPEMIDLTIAVHNGKDHVPVFITD-NMVGH KLGEFAMTRTFKGHS------G---DR----KAK------GK >GAMMA_Legionella_pneumophila_Paris Concatenation of 2 sequences MALLKSKPTSPGKRGEIRVVHHD-IYKG------------KP-HAALVEKLKKTGGRNNQGRITVRH-IGGGQRQK---- YRIIDFK-R--NK-DGILGRVERLEYDPNRTALIALISYK-DGEKRYIIAPSNLEVGATIQSGA-D-SP-ISVGNCLPLK NIPVGTTIHCVEMKPGKGAQMLRSAGCSGQLVAK--EGVYATLRLRSGEMRKIHVLCRAVIGEVSNSEHNLRALGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGLPTKGYKTR-SNKR-TD-T-FIVRGR --------------------------------MMI---G-LLGRKIGMTRVFT-PEGV---------SVPVSVVEVQPNR VSQVK----TAA----N--DGY--SAVQLTG-------GT--KVSK----------PVAGHFK----------------- ---AQ-IDAGDMQVEFRI--------DSEDAF-----TP---GQ-VISV-AD-V-FTAGQYVDVSGLTKGKGFAGTVKRH NFRT-QDASHGNSRSHRV-PGSIGQN-QTPG-RVFKGKKMAGHMGNARCTIQSLELVKVDSERN---------------- ----------LLLIKGA-IPGAPGSRVEIK--MEITTID-TK-----SKLKLNKEIF----AY-TY-NEGLVHQAVVTFM NNARSGNSAQKTRSE--------VS-GGGKKPW---------NQKGTGRAR--------AGT---IR-SP----LW---- RSGGVTFASK-K-RDYSQKLNKKMYKRALRSIISELCRTG----------------N-LMVVSDF----QCD-N------ --HKTKLII--MSEVG--E---NEYLGSRNLIDYD-I---------------CDVTTIDPVSLLRFEK----VVVTEAAI KKIEARLKEFYKKDV----VTMMMKRFNYSSVMEVPRILKITLNMGVG-EAVGDKKVMNHAIEDMTLISGQKPVVTKARK SIAGFKIREGWPIGCKVTLRRERMYEFLDRLISITLPRVRDFRGLNP-KSFDGTGNYSMGIHEQIVFPEID-----YDKT DGIRGLDICITTS-----------------------AKTNEEAKALLEAFNLPLMSRVA-K--APVIHSANVEVTFV--- -D-G----VITVKGPKGILTQKI--NK-LVNIQHSKES-NK--LEF----S-P-ASNDPMGW-AQAGTARALVRNMVQGV TEGYTVTLELVGVGY--RAQSKD-KS--ISLS--LGYSHSIEYDL-P-K-GVTVETP--N-NTTILLKG-VDKQVLGQIA SEIRAFR------PPEPY---KGKGVKYAGEQIVRKEAK----------MIQMQTVLEVADNSGARKVMCIKVLG-SHRR Y--ARVGDVIKVSVKDAIPR-S-------KVKKGAVMRAVVVRTAQGVRRDDGSLIRFDDNAAVLLN-NQNE-PIGTRIF GPVTRELR--ERFMKIISLAAEVLMN-L--NTLSPDPGS-RPSRRRVG-RGIGSGL-GKTCGKGHKGQKSRAGGY-H--- -KINF-E-GGQMPIQRRLPK-MG--FKSVSLGELIDLVALRKA-GLINVK---------VIL--SGE-L-T-A-A-IKL- KGLRVTKGARSAIESLGGSI-K---QMK--GRN---RGLA-LRGSKISFG----------EFGLKAV--ERGRLTARQIE AARRAMTRHI------KRGGKIWIRVFPDKPITQKPLEVRQGKGK---------GSVEYWVAQIQP-GKVLFEM--EG-- VSKELAMEAFDLAKAKLPFKVMF-EKQNARHRRGLKAKALI----RKTGRSRLVVYRSGVHIYSQIVKS---DQLGDKVL VASSTI-DKEL-RSSL----TGK-SKVEQASLVGQLLGKR--AKAAG-ITQVAFDRAGYKYH--GRVKALAEGAREAGLD F--------------------------------------------------------------ME-VTAKLKGAPLSAQK GRLVADMIRNMNVSGALDVLKFT---------------------------------PKKGAKLMLKLLESAIAN----A- ENNN-GADIDDLKVGMVCVDEATTLKRISPRAKGRANRICKRTCHITIKVSDMKRIKSGDEVIVIAGK------SK-GHI GKVLRVVDD----AVV--VEGGNLIKKHIK----PN-PQKPENK-GGIIAREAPLHVSNVA-HYNPVT-------KK--A --DKVGFKY---LE--------SNKVR---YYKSNN---EII--MGQKVNPIGIRLG--II-KDWNSKWFA------G-K R--YAEFLIQDIKLRNDL--KKKLM-----AAAVSKILIERPA-N-NAVVTILTARPGVIIGKKGGGIETLRKEISDNVH LNIEEVKK---PELDATLVAEGIAQQLEQRVMFRRAMKRAVTSALKA-GAKGIKICVSGRLGGAEIARSEWYREGRVPL- -HTFRADIDYGTAESKTTYGIIGVKVWIFMSMHDPIADMLTRIRNGQQAKHQQVTL-VSSKLKEEIARVLKEEGYIQDFF TET--LPN--------GLKSITLKLKYY----HG-------R---PVIEFIKRISRPGLRVYKSYKDLHSI-PGFGVAIL STSKGIMTHVSAKVKGVGGEVICEVASSNQNIKIRLKSFDHRLIDLSTREIVDTAKRTGAQIRGPIPLPIRKEKFTVLTS PHVNKDAR-DQYELRTHKRLVVIVHPTEKTVDALMKLDLAAGVDVQISLARTMIGKVVSDKMDKTIVVMIERTVKHPKYG KIMKRRTKLHAHDEN--QVCRVGNTVKIRESRPLSKTKSWVLVEVIS--------------------------------- -MARSI-RKGPFIDH-HLISKVEAAIE---SKSKK----PIKTWSRRSTIVPEMIDLTIAVHNGKDHVPVFITD-NMVGH KLGEFAMTRTFKGHS------G---DR----KAK------GK >GAMMA_Leptospirillum_ferrooxidans_ATCC_53993 Concatenation of 2 sequences MALIKTKPTSAGRRFVVKTIDTR-LHKG------------NP-HSALVEVQSHSGGRNNLGRVTRRH-QGGGHKSH---- YRLVDFK-R--NK-LDIPGKVERLEYDPNRSAHIALICYV-DGERRYILAAKGMSVGDPVLSAE-Q-TP-IKPGNCMPLR GIPVGSVVHNVEMRPGKGGQIARSAGASVQLMAR--EGDYAQLRLRSGEVRRIHVSCRATIGEVGNEEHGSRQLGKAGAT -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGQPTKGYRTR-RNKRTSN---MIVRRR --------------------------------MVM---G-LIGRKVGMTRIVA-GDGR---------VLPVTVIHVAPNT VAQVK----DIA----T--DGY--CAVQVAT-------GT--RVTS----------ALAGHFK----------------- ---NG-IAPGRLLREFRV--------ADTANY-----AC---GM-DIDL--D-I-FAEGQRVDVSGVSKGKGFAGAIKRH NFRS-NRASHGNSLSHRA-PGSIGCR-QTPG-RVFKGKKMAGHLGAEQVTTLNLELVRIDANRR---------------- ----------LLMIKGA-VPGARDGDVMIR--MQVQSLE-VTTGKS-SEIEIADGVF----GV-PY-NEALLHQVVVAQM AGMRSANAVQKNRAA--------VR-GGGRKPW---------KQKGTGRAR--------AGS---IR-SP----IW---- RGGGRAFPGG-N-ENYTQKVNKKMWAGAMRTVLAELLRQG----------------R-LQIIQQE----DFG-E------ --PRSRLLV--MGEVP--L---NLFLGLRNFPRVG-I---------------AGWQDVGPADLLQYGR----VLLDVEAA ARLGARLHALYKTSI----APKLMQEFGFSSVMEVPKLLKITLNMGVG-EAVGDKKVLEAAVGDMTRIAGQKPVVTRARK SVAAFKIRDGYPIGCMVTLRGIVMYEFLDRLVSVAIPRIRDFRGLSP-KSFDGRGNYTMGVKEQIIFPEIE-----YDKI DRLRGLDVVFTTT-----------------------AKNDEEGLGLLKAFKMPFMSRVA-K--QPVPLPKGVEVH-V--- -A-D--Q-RLVVKGPKGEMSVPF--HP-A--VELRIDD-GG--ASL---------TWSDNQN-AQAGTMRAILNNMVQGV SQGYEQKLEIIGVGY--RAQAKG-KT--LSLS--LGFSHPVDYSV-P-D-DITIETP--T-QTEIVIRG-IDKQKIGQIA ADIRAYR------PPEPY---KGKGVRYAGENVRRKEAK----------MIQTQTRLNVADNSGAREVMCIKVLG-SHRR Y--ADIGDVIKVSIKDAVPR-G-------KVKKGDVYNALVVRTRKGVRREDGSLIRFDSNAAVLLN-NQLQ-PIGTRIF GPVTRELR-GANFMKIISLAPEVLMK-L--NTIAPAEGS-KKDRRRVG-RGIGSGF-GKTAGRGHKGQHARSGGY-H--- -KVGF-E-GGQMPLQRRIPK-RG--FRNVALSQLVDLEGLLLR-RIVRVK---------VIL--TGE-I-T-Q-G-LTV- RGLRVSAGARAAIEKAGGKV-K---QHK--GRN---RGVA-TRGSKVSFG----------EFGLKAV--GRGRITARQLE AARRAISRHV------KRGGRIWIRIFPDKPISKKPAEVRMGKGK---------GNPEYWVALIQP-GKVLYEM--EG-- VTEEVAREAFALGAAKLPVQTAF-VKNLARLRRARKTRARI----ASQAKPRLCVFRSGRHIYAQVIDD---S--QGKVL AQASTV-EGEL-RASM----GRG-ADVAAAATIGQRVAAK--ALAVG-VKEVAFDRSGYRYH--GRVRALADAAREGGLS F--------------------------------------------------------------MK-SSAVLKGLQMSPQK ARLVADLVRGQPVGKALEILRFT---------------------------------TKKAALPIRKCLESAIAN----A- ENNE-GADVDALVVEQIMIDGGAVLKRFAARAKGRGSRILKRTSHITVVVAEMLKVRKDDEVVVLAGK------DK-GKR GKVLKVLREDS--RVL--VEKVNMIKRHVR----PD--RM-GKA-GGIVEKEAPIHVSNVA-IFNAAT-------GG--G --DRIGYKV---LE--------DGKVR---VFKSNG---EVI--MGQKTNPIGLRLG--II-KNWNSRWYG------K-S D--FQEKLLEDIKVRQFI--RERLA-----GGAVSDIIIERPA-R-SARITVHTARPGIVIGKKGEDIEKLRHDVQKRVH INVEEIRK---PELDAQLVAESVAQQLVRRIMFRRAMKRAVTNAMRF-GALGMRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGFAEANTTYGIIGVKVWIFMSVTDPIADMLTRIRNAQQVNKAKVRM-PASKLKRAIARVLVEEGYIQEVK EDV----A---N----GHPVLDLTLKYY----AG-------A---GVIAEIRRVSRPGVRVYRGAEDLPRVRDGFGIAII STSQGIMTDRAARSAGIGGEVLCVVSMDSSKIRIRLKSYDYRMLDISAAEIVETARRTGARVCGPIPLPTKIERFTVLRS PHVDKNAR-DQFEQRTHKRLLDILDPNDKTVDALIKLDLAAGVDVEIKL-RSLVGTVVSNLMDKSIVVNVERRIQHPLYK KYIRRSKKFHAHDAE--NICHIGDIVKIEECRPLSKTKSWRLVSVLAEG------------------------------- -MPRSI-KKGPFIDE-HLDRKVQSAQA---SNSRR----PIKTWSRRSTITPDFIGLTISVHNGRQHIPVVVNE-NMVGH KLGEFALTRTFKGHV------A---DK----KAK------R- >GAMMA_Magnetococcus_sp_MC-1 Concatenation of 2 sequences MALKNFKPTSDGKRHQVAINYSE-LSNE------------GP-ERSLLAPLKRTGGRNNNGRMTVRH-QGGGHKRR---- YRIIDFK-RN--K-FDVPAKVARIEYDPNRTAFIALLHYA-DGEKSYILAPQRLQVGDTVVSAKDN-VD-VKPGNCMPLR VMPIGTIIHNVELKPGKGGQVARSAGNYIQLMGK--EGKYAQLKMPSGEMRLVLLECMATVGMVSNPDNSNTKIGKAGRT -RWM-----GKR-P-SVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVTP---WGVPTKGKKTR-SKTKASD-R-LIMRRR --------------------------------MRS---G-LIGRKLGMSQMFT-EDGQ---------RIPVTLVQLGPCA VVAKR----SDE----Q--DGY--NAVQLGF-------EE--ALSK----------TVRGQYK----------------- ---AN-VTPRRVLREFRV--------SNPESY-----EV---GQ-ELTA--E-Q-FAVDSFVDVTGKTVGKGFAGVMKRW GFRG-GRASHGAHKVHRS-GGSIGQC-QTPG-RVYKNKKMAGHMGQQTRTVQNLKVAYVDAVQS---------------- ----------IIAVKGS-IPGSKGSLVLVR-MIQVPVKD-ANNQEV-RSTELNESVF----GR-EI-RADLLGMAVNYQL AKRRLGTATVLGRSD--------VR-GGGKKPY---------RQKGTGNAR--------QGT---IR-AP----QF---- RTGGIVFGPQ-Q-RDYSHKLNKKVRKLALQTALSVKASSE----------------E-MVVVDKL----ELA-S------ --IKTKFLV--VKELS--N---EIVLSARNIPNVM-V---------------ADVDGVNVYDLLRYEK----LVITEEAV RSLEADLKQVYHDKV----VPELQAKFGYSNVMQVPRLQKIVVNMGVG-EAIADKNFLNNAIGNLEAITGQKAQTTYAKK SIAGFKLREGQAVGCRVTLRRRQMWEFLDRLINAALPRVRDFRGVSE-KAFDGRGNYTMGIKEQIIFPEID-----YDKV DKVRGMDICIVTS-----------------------AKTDDEARQLLAGFNMPFMSRIG-K--KPVVVPDGVDLK-I--- -N-G--T-VVTAKGKLGELTRQF-HEA----ITFAQEG-KE--VNV----A-V--SGTKKSS-SLWGLSRTLLDNMVVGV SQGFSKQLEIQGVGY--RAAVKG-RT--LELS--LGFSHPVNYEL-P-N-GLEATVE--K-NTLITVKG-YDKEVLGQAC AEIRSWR------PPEPY---KGKGVRYVGEFVLRKEGK----------MIQVESRLEVADNSGAKKVQCIKVIG-SKRR Y--ARVGDVIIVAVKAALPR-G-------KVKKGEVARAVVVRTKKEISRPDGSLIRFDKNAAVLIN-KAGE-PVGTRIF GPVTRELR-ARNYMKIISLAPEVLMK-L--NEIPAVPGN-QQSRNRVG-RGPGSGN-GKTAGRGHKGQKARSGGF-H--- -KSGF-E-GGQMPLQRRLPK-RG--FKNVQVEDLVNAEALNDL-GLLGIK---------LLA--NGD-I-T-K-A-ITV- YVDKASAAAVAKMEAAGGKV-K---AHK--GRV---HGLA-YRGSSLSFG----------QFGLKAM--ATARITARQIE AARRAMTRHI------KRGGRVWIRIFPDVPVSQKPAEVRQGKGK---------GSPEFWIARVKP-GRILYEM--EG-- VDEQLAREAMQRAAAKLPVKTKF-IRNQARKARSARVRSRI--KKVQGERPRLSIFRSARHIYAQIIDD---K--QGRTL VSASTV-EKDL-REDM----KNG-GNADAAAFIGKRIAEK--AKEQN-ITEVVFDRGGFLYH--GRTKALAEAAREAGLN F-------------------------------------------------------------MQE-ARATTKYQRVSPYK VRLVIDQIRGMQVESAMNLLAFS---------------------------------KKRVAGVVRQTLKSAVAN----A- EENL-GLDVDTLVVSQAYVDQGPSMKRFKPRARGRATRILKRTSHITVAVCPSTDLKKGDTVIVVAGK------DK-GKQ GQILQVLGKKS--SVL--VEKVNMIKRHTK----PA----QNRE-GGIVEKEAPIHISNVM-IVDPAT-------GK--A --TRIKKKN---LE--------DGKVR---VAAGSG---EVL--MGQKVHPTGFRLG--TT-KTWDTRWFA------D-R N--YADLLLEDIKIRAWL--KKRLA-----HASVSKIVIERPA-Q-KARINIHTARPGIIIGKKGGDIEKLKNDIKAIVQ INIVEIRK---PEADAQLVAENVAQQLERRVAFRRSMKRAVTSAMRL-GAEGIRINCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDYGFAEAHTTYGIIGVKVWVYMSMNDPISDMLTRIRNAQMVGKDSVRM-PASKMKKRIADILKEEGYIESIS ESV----D---EA---NHTTLELTLKYY---QNK-----------PVIEEIKRISTPGRRTYVGKAEIPSVYQGLGIAIL STSKGVISSRRALELGVGGELLCTVYMESQKIRIRLKAFDHRILDQSTGEIVQTARRTGADIRGPIPLPTKINRYTVLRS PHVDKKSR-EQFEIRTHKRIIDIVNPTPQTVDALMKLDLAAGVNVEIKLKRIMQGVVVSDKMDKTVVVLVERKVRHPLYG KIVRQSKKYKAHDEE--NQYRTGDMVMIQESRPLSKDKNWVVTE--RTA------------------------------- -MARSV-KKGPFLDD-FLVKKVDVLRE---GSRKE----LIKTWSRRSTIIHEFVGYTFGVHNGRKFIPVLVTE-NMVGH KLGEFAPTRTYYGHG------V---DK----KAK------RR >GAMMA_Mannheimia_succiniciproducens_MBEL55E Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLDTKSKTGGRNNLGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSAGDQIQAGV-N-AP-IKVGNALPMR NIPVGSTVHNVELKPGKGGQIARSAGSYVQIIAR--EGNYVTLRLRSGEMRKVLAECTATIGEVGNSEHMLRVLGKAGAN -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVSP---WGVQTKGKKTR-HNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRIFT-EEGV---------SIPVTVIEIEANR VTQVK----TLE----N--DGY--SAVQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRTE---------GEEF-----TL---GQ-EINV--D-I-FADVKKVDVTGTSKGKGFQGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGAERVTVQSLEVVRVDAERK---------------- ----------LLLVKGA-VPGATNSDVIVK--MELQVVG-A------NALAVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGITFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LVVVDKF----EID-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFNK----VVVTVDAV KQIEAKLHDYYRDQV----VNELKTKFNYASVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFLERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAAFNFPFMSRVA-K--APVSVPAGVEVK-L--- -D-G--Q-LLTVKGKNGELTRTI--HN-F--VEVKQDN-NE--LTF----S-P-RNDGAEAN-AQAGTTRALVNAMVIGV TEGFTKKLQLVGVGY--RAQVKG-NV--VNLS--LGFSHPVEHTL-P-A-GITAECP--S-QTEIVLKG-ADKQLIGQVA ADIRAYR------SPEPY---KGKGVRYSDEVVRTKEAK----------------------------------------- -------------------------------------------------------------------------------- ------------------------MY-L--NTLAPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLNDLVTLESLKAA-NIITAK---------VVL--AGE-V-K-G-A-VTV- RGLRVTKGAKAAIEAAGGSV-K---VHK--GRN---RGIA--AGTDVSFG----------TYGLKAI--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEIAREAFALAAAKLPIKTTF-VKKSARIRRAARARHMM----RENGVTRLVIHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKAI-SEQV----KYT-GNKDAAAVVGKLVAER--ALAKG-IKDVAFDRSGFKYH--GRVQSLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAAALEILTYT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLTGK------DK-GKR GKVTQVLPN-G--KVI--VEGVKIITKHEK----PV-PAL-GKE-GGLVKKEAAIDVSNVA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EIIA-MGQKVNPHGIRLG--IV-KPWSSTWFA------NTQ D--FASNLDGDFKVRKFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVAKIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAASKVAISM-PSSKLKVAIANVLAAEGYIESVK VLE--------G----AKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTVQGRVISDKMDKSFTIAIERKVKHPLLG KFIRRTTKLHVHDEN--NEARIGDTVEIKECRPVSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Marinobacter_aquaeolei_VT8 Concatenation of 2 sequences MPIVKTKPTSAGRRHVVKLYNPD-LHKG------------RP-YEPLVETKSKSGGRNNVGRITTRH-IGGGHKQH---- YRVIDFK-R--TK-DGIPAVIERLEYDPNRSAHIALVKYA-DGERRYIIAPKGMKAGDPVRSGV-D-AP-IKVGSTLPLR NIPVGSVIHCVELKPGKGAQLARSAGASVQLVAR--EGAYATIRLRSGEMRKVLVDCRATLGEVSNSEHSLKQLGKAGAS -RWR-----GKR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGHKTR-KNKR-TD-K-MIVRRR --------------------------------MAI---G-VVGRKAGMTRIFT-DEGQ---------ALPVTVIEVEPNR ITQLK----TLE----S--DGY--RAVQVTV-------GS--RVNK----------AAAGHFK----------------- ---AG-VEAGRGVWEFRL------ADGEGEDL-----AA---GG-ELTV--S-V-FEDGQVVDAVGQSKGKGFQGGVKRW NFSM-QDATHGNSLSHRA-PGSIGQN-QTPG-KVFKGKKMAGQMGNAQVTVQNLKIVRVDAERN---------------- ----------LLLVSGA-VPGATGGDVVIK--MELTITG-SG-----KGISVSDAAF----AK-DF-NEALVHQVVTAYM AAGRQGTKAQKTRSE--------VS-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RSGGVTFAAK-P-RDFEQKVNRKMYRAAMRSIFSELVRQE----------------R-LVVVDDM----NVD-T------ --PKTKLIL---SENE--Q---NLHLASRNVPHVD-V---------------RDVAGLDPVSLVAFEK----VVVTVPAL KKIELNMKEQYTKEV----VPALQKEFGYKNVMQVPRIEKITLNMGVG-EAVGDKKLIENAVADLERLAGQKVVVTKARK SVAGFKIREGWPIGCKVTLRGERMWDFFDRLVHIAVPRIRDFRGLNP-KSFDGRGNYSMGVREQIIFPEIE-----YDKV DKIRGLDITITTT-----------------------AGTDDEGRELLKAFGFPFMSRVA-N--NPVVLPSGVEVK-L--- -N-G--Q-EINVKGSKGALQFTI--HQ-A--VEVKQEE-NV--LRF----A-A--RDGKQSR-ALAGTTRALVNNMVTGV STGWERKLQLTGVGY--RAQAQG-KK--LNLT--LGFSHPVEYEL-P-E-GVTAETP--S-NTEVVIRG-IDKQQVGQVA AEIRAFR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQTQTMLEVADNSGARQVMCIKVLG-SHRR Y--ATVGDIIKVTVKEAIPR-G-------KVKKGQVLKAVVVRTRKGVRRPDGSLIRFDGNAAVLLN-NQDA-PIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NELAPEPGS-RPSAKRVG-RGIGSGL-GKTGGRGHKGLKSRSGGS-V--- -APGF-E-GGQQPLARRLPK-FG--FTSIRLNELVDLAALKKA-DIIRAK---------VIL--SGE-L-D-R-A-VTV- KGLRVTKGAREAITAAGGKV-K---VMK--GRN---TGLA-QRANKVSFG----------EYGLKAT--SRGRITARQIE AARRTMTRRI------KRGGKIWIRVFPDKPITGKPLEVRMGKGK---------GSVEYWVAEIQP-GRMLYEM--EG-- VAEEIAREAFTLAAAKLPVQTTF-VANNERLRRARKVRMKI----RELGTDRLCVHRTPRHMYAQVTTA---D--GSKVL ATASTL-DKEL-RQ------GAT-GNVDAAKKVGQLIAER--AKAAG-IEKVAFDRSGYRYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-VAAKYKGARLSAQK ARLVADQVRGKAVEDALNILTFS---------------------------------PKKAAVVIKKALESAIAN----A- EHNE-GLDVDDLRVSTVMVDEGPTLKRIKARAKGRADRIFKRTCHITVKVADMKKIKRDDEVIVTTGK------DK-DKR GKVLKVLDD-G--RVL--VSGINMMKKHTK----PN--PMLGTP-GGIVEKEAPIQASNVA-IFNPQT-------GK--A --DRVGFQI---KE--------DGKVR---IFKSTN---EAV--MGHKVNPTGIRLG--VI-KEHNSVWYA------DKK D--YAKNLLNDIQVREFL--DKRLV-----KASVSKIVIERPA-Q-NARITIHTARPGIVIGKKGEDVDRLRREVSDMVH INIEEVRK---PDLDARLVAQNVAGQLERRVMFRRAMKRAVQNAMRQ-GAKGIKIQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWIFMSMQDTLADMFTRIRNAQMASKADVTM-PSSKMKVSVAQVLKDEGYVADFS VSA----D---A-----KPELTITLKYF----GG-------K---PVIEEIQRVSRPSLRQYKGAGELPKVAGGLGVAIV STSRGVMTDRAARAAGVGGEVICTVFMQSQKIRIRLKAFDYRLIDQSTQEIVDTAKRTGAQVRGPIPLPTRKEKYTVLIS PHVNKDAR-DQYEIRTHKRLLDIVEPTEKTVDALMKLDLAAGVDVQISLARTLSGKVVSNKMDKSIVVLVERQVKHPLYG KYMKRSTKIHAHDES--NQCNIGDTVTIQETRPVSKTKSWALVEVTERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEAALE---ANDKR----PIKTWSRRSTVFPEMVGLTIAVHNGKQHVPVYVTE-DMVGH KLGEFAATRTYRGHA------A---DK----KAK------R- >GAMMA_Marinomonas_sp_MWYL1 Concatenation of 2 sequences MAVVKSKPTSAGRRHVVKVTNND-LHKG------------AP-YAPLLDTKSKSGGRNNNGRITTRH-VGGGHKQH---- YRMVDFR-R--NK-DGISAVVERLEYDPNRSANIALIRYA-DGERRYIIASKGMVAGNIVFSGA-D-AP-IKAGNTLPLQ NIPVGSTVHCVELKPGKGAQVARSAGASAQLVAR--EGRYVTLRLRSGEMRKVLTECRATLGEVSNSEHSLRVLGKAGAT -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEGRS----KGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-LIVRRR --------------------------------MAI---Q-LVGRKAGMTRIFT-EDGV---------SVPVTVIEVEPNR VTQVK----TAE----T--DGY--QAVQVTV-------GS--RVNK----------AAAGHYK----------------- ---AN-VEAGRGLWEFRL-------AGDEKEI-----NV---GD-ELTV-AD---FESIQMVDVTGQSKGKGFQGAIKRH NFSM-QDATHGNSLSHRA-PGSIGQC-QTPG-RVWKGKKMAGHMGAAQVTTQSLEVVRVDTERN---------------- ----------LILVKGA-VPGAVNGDVILQ--MNLNLTG-AE-----GTVEVSDVAF----AR-EY-NEALVHQVVTSYL AGARQGSRAQKTRSE--------VA-GGGRKPW---------KQKGSGRAR--------AGT---IR-SP----LW---- RSGGVTFAAK-P-QDHSQKVNKKMYRAAMRTIWSELVRQD----------------R-LVVVEDL----KLE-A------ --PKTKLIV--SHDLD--D---NLFLAARNIPNVD-V---------------RDAASIDPVSLIAYDK----VLVTVGAL KQVEARLKQVYKDQV----VAKLTEEFSYKNVMEVPKITKITLNMGVG-EAIADKKLLEHAVNDLEALSGQKVVVTKARK SVAGFKIRDGYPIGCKVTLRGERMWDFFDRLVDVAIPRIRDFRGLNP-KSFDGRGNYSMGVKEQIIFPEID-----YDKV DRVRGMDITITTT-----------------------ARTDEEGRALLAAFSFPFMSRVA-N--SPVTLPSGVDLT-L--- -N-G--Q-TVVVKGGKGSLEFNI--HT-S--VQVSKEE-NV--ITF----A-A--RDGKQSR-ALAGTTRALVNNMVVGV SQGFEKRLFLQGVGY--RAALKG-NV--LNLS--LGFSHPVDYEL-P-E-GVTAECA--S-QTEIVIRG-IDKQAVGQVA AEVRGFR------PPEPY---KGKGVRYSDEVIRRKEAK----------MIQTESMLDVADNSGAKRVQCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------RVKKGQVLNAVVVRTRKGVRRSDGSVIRFDVNSAVLLN-ASGQ-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMF-L--NTLRPGEGS-KHAPKRVG-RGIGSGL-GKTGGRGHKGLKSRSGGS-V--- -KPGF-E-GGQMPLQRRLPK-FG--FTSVRLNELVDLAALKSA-DILGAR---------VIL--SGS-I-D-K-A-ITV- RGLKVTKGARAAIEAAGGKV-K---MQK--GRN---RGLA-LRGNQVSFG----------EFGLKST--ERGRLTARQIE AARRAMTRHI------KRGGRIWIRVFPDKPITQKPLEVRQGKGK---------GSVEYWVAQIQP-GKMLYEV--EG-- VSEQLAREAFALAAAKLPLSTTF-VKKQSRIRRARRARLHI----RDLGANRLTVHRTPRHMYAQVISP---C--GSKVL ASASTL-EEAL-RG------SAT-GNKVAAKEVGTLIATR--AKAAG-VTSVAFDRSGFKYH--GRVQVLADAAREAGLE F-------------------------------------------------------------MSE-VKASLKGARLSAQK ARLVVDQIRGKSVSEALNILTFS---------------------------------PKKAAVIVKKVLESAIAN----A- EHNE-GADVDDLRVSTAYVDEAMTLKRIMPRAKGRADRILKRGCHITVKVADMRKIKRNDEVIVIAGK------DK-GKR GKVVKVVGE-N--RVL--VSGVNTVKKHEK----PN--PMKGST-GGIVEQEAPIQVSNVA-IYNSAT-------GK--A --DRVGFKL---NE--------DGKVR---VFKSNS---EAI--MGQKVHPTGIRLG--IV-KDHTSTWYA------NNQ N--YSKLLLNDLQVRAFL--EKKLV-----QASVSRIEIQRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRNAVSEMVH INIEEIRK---PEMDAKLVAQNIASQLERRVMFRRAMKRAVQNAMRA-GAKGIKVQVSGRLGGAEIARAEWYREGRVPL- -HTLRADIDYATYEAATTYGIIGVKVWIFMSMQDTLADMFTRIRNAQMAAKTSVSM-PSSKMKSSIAAVLREEGYVGDFS VDE----A--------VKPTLTIELKYY----EG-------K---PVIEQIKRASRPSLRQYKGTSALPKVEAGLGVAII STSKGVMTDRAARAAGIGGEVICTVFMQSQKIRIRLKAFDHRLIDASTQEIVDTAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYEIRTHKRVLDIVEPTEKTVDALMKLDLAAGVEVQISLARIATGKVVSDKMDKTITVLVERTEKHPLYG KFIRRSTKLHAHDEN--NECQIGDLVKVVETRPYSKSKTWKLVQVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEAAVE---KNDRR----PIKTWSRRSTIFPDFVGLTIAVHNGRQHVPVLVTE-DMVGH KLGEFAPTRTYRGHA------A---DK----KAK------R- >GAMMA_Methylococcus_capsulatus_Bath Concatenation of 2 sequences MALIKQKPTSAGARFVTRVRSEE-LYKG------------EP-YAKLLEKQTRSSGRNNQGRVTTRH-KGGGHKQF---- YRIVDFK-R--DK-IDIPARVERIEYDPNRTAYIALVLYR-DGERRYIVAPAGLSAGSEIVAGE-F-AA-IKVGNSLPLR NIPVGTVVHCVEGKPGKGAQYARSAGTSIQLVAK--EGEYATLRMRSGEMRKVLADCKATIGEVSNNEHNLVSLGKAGAS -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGIPTKGYKTR-NNKRTDG---LIIRRR --------------------------------MAI---G-LVGRKCGMTHIFT-DAGA---------AVPVTVIHVEPNR VVQVK----TLE----S--DGY--RAIQVTT-------GS--KLTK----------ADAGHYK----------------- ---AG-VEAGRGLWEFRL-------EDSDQDY-----TV---GT-ELGV--G-V-FAEGQFVDARARSIGKGFAGVVKRH NFRT-QDATHGNSLSHRA-PGSIGQN-QTPG-RVFKGKRMAGHMGDKNITVPNLRIVGIDAERS---------------- ----------LLLVKGA-VPGTKGADVIVR--MSLSIPK-IENGAA-GDLEVSDKVF----GQ-GF-NESLVHQLVVGYL AAARSGTKAQKSRSD--------VS-GGGKKPW---------KQKGSGHAR--------AGT---TR-SP----LW---- RTGGVTFAAS-N-RNYRQKLNKKMYRAAVRSIFSELLRQG----------------R-LVVSDGI----VPT-S------ --PKTRVIL--AEQLD--L---NLALSSRNLPNVS-I---------------NTADTLSPVDLVHAER----VIATSSAI RKLEARLENHYKEKV----VPELMARFGYKSVMEVPRLVKITLNMGVG-EAVADKKILQNAVENMQAIGGQKPIVTHARK SIAGFKIREGMPVGCKVTLRRARMYEFLDRLISVAIPRIRDFRGLNP-KAFDGRGNYSMGVREQIIFPEID-----YDKI DAIRGMDITITST-----------------------AKTDAEAKALLEAFKFPFMSRVA-N--NPISIPKGVEVT-I--- -A-D--G-IVTAKGKNGLLSRTV--PA-E--LGVDLEG-GT--LSI----R-Y--NKNQRQN-ALAGTTRANLANMIVGV SNGFERKLSLVGVGY--RAQAKG-DV--LSLS--LGFSHPVEFKV-P-A-GVVVETP--S-QTDIVVKG-ADRQVVGQVA ADIRAFR------APEPY---KGKGVRYADEVIIRKEAK----------MIQMQTCLDVADNSGARQVMCIKVLG-SKRR Y--ANVGDIIKVSVKDAIPR-G-------RVKKGEVYNAVVVRTRKGVRRADGSLIRFDNNAAVILN-NQHQ-PIGTRIF GPVTRELR-SEKFMKIISLAPEVLMF-L--NTIGARDGS-RPEKKRVG-RGIGSTL-GKTCGRGHKGQKARAGGF-H--- -KVGF-E-GGQMPLQRRLPK-VG--FRSVTLTQIIGLAELKEA-GLVPVK---------IIA--TGS-V-G-G-V-VTV- RGVGVTRGARAAIEAAGGKV-K---QHK--GRN---TGVA-IAGSKVSFG----------EYGLKAT--TRGRITARQIE AARRTISRHV------KRGGKIWIRVFPDKPVSKKPLEVRMGSGK---------GSVEFWVAEIKP-GTMLYEL--EG-- VSEELAREAFRLAAAKLPVQTTF-SKKQARLKRAAKTRHVI----RAMGANRLTVHRTPRHIYAQVISP---D--GGTVL AAASTL-ESAI-RETL----PVT-GNKDAAIAVGRRIAEK--ALAVG-ISSVAFDRSGFKYH--GRVKALAEAAREAGLQ F--------------------------------------------------------------ME-ALSRHRTARISPQK CRLVADQIRGLNVAAALDLLTFS---------------------------------NKKAAGLVKKVLQAAIAN----A- EHNE-GADVDELRVKTVFVDEGPVLKRMSPRAKGRANRILKRTSHITVLVSDMRRIKKGDQVIVIAGK------DK-GKK GLVLSVLSG-D--KLV--VEGVNLVRKHQR----PN--PMRGVT-GGIVEKAMPIHSSNVA-LFNAAI-------NK--G --DRVGFRL---LA--------DGKVR---FYRSTN---ELI--MGQKVNPTGIRLG--YI-KDWSSRWFA------DSK S--YPVFLNNDLKVREFL--KQKLK-----HASVSRIQINRLA-N-NAQITIHTARPGIVIGKRGEDIDALRRDVSRFVQ VSVEEIRK---PELDAQLVAEGVAQQLEKRIMFRRAMKRAVQNTLRV-GAEGIKISVAGRLNGAEIARTEWYREGRVPL- -HTFRADIDYGFAEAVTTYGVIGVKVWIFMSMSDPLSDLLTRIRNGQAAGKAEIIV-PASKLKRAVCQVLKEEGYIAGFS DVT----E---Q----GKHNIRVELKYH----NG-------A---PVIDKIQRVSKPGCRRYRGRDELPKVMGGFGIAIV STSKGVMSDRRARSVGEGGEVLCVVEMAKQRIRIRLKAFDHRLIDQSASEIVETAKRTGAQVLGPIPLPTKKERFTVLVS PHVNKDAR-DQYELRTHKRLMDIIEPTDKTVDALMRLDLAAGVDVQIKLVRSVTGRVVSNKMDRTIVVAIERQVSHPLYG KYIRRTTKVLAHDEN--NECSIGDLVTLHASRPISKKKAWTLGAIVERA------------------------------- -MPRSI-KKGPFVDH-HLMKKIDEANA---TGAKK----PIKTWSRRSMVLPEMIGKTIAVHNGKQHVPVLVSD-NMVGH KLGEFAPTRTYKGHQ------A---DK----KSK-------- >GAMMA_Nitrosococcus_oceani_ATCC_19707 Concatenation of 2 sequences MPIVKAKPTSAGRRFVVQVTSLE-LYKG------------RP-HPALTKKLSKSGGRNNQGRITVRH-CGGGHKRL---- YRIIDFR-R--DK-IDVLGRVKRIEYDPNRSAHIALINYS-DGEKRYIIAPKAVKVGDIITSGR-E-AP-IRDGNCLPLR NIPVGTLVHCIELKPGKGAQIARSAGSSCQLVAR--EGDHAMLRLRSGEIRKVPLECRATIGEVGNDGHGLRSLGKAGAM -RWR-----GKR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-RNKRTGK---FIVRRR --------------------------------MAI---G-LIGRKVGMTRVFT-DEGA---------SIPVTVIEATPNR ISQVK----TLE----Q--DGY--QAVQVTV-------GE--RVTS----------SLKGHFK----------------- ---AN-VEPGRKLQEFRF------GAEEGRDI-----KA---SG-ELKV--D-L-FEVGQKVDVTGITRGRGFAGVVRRY HFGG-GDASHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGQMGNVRRTVQNLELVRIDEGRQ---------------- ----------LLLIKGA-IPGAPGGDVIVK--MNLAVQSLAENSET-GMTQLSDTVF-----TQHF-NEPLIHQVVTAYL AKARAGTHAQKTRSE--------AR-GGGAKPF---------RQKGTGRAR--------AGT---IR-SP----LW---- RGGGRAFAAK-P-GDYSQKVNRKMYRAAMRSILSELVRQD----------------R-LRMIDKI----MLS-K------ --PKTRLIV--VAEDD--R---NLELSARNIPTVA-I---------------RNVSRVSPVELIRFDG----VLVTGDAI RCFEARLQKHYRDTV----INQLRERLGCQSVMAVPRIEKITLNIGAG-EAVGDKKILERVMGDMARISGQKPVLTRARK SVAGFKIREDWPIGCKVTLRRKQMYEFLDRLINIAIPRIRDFRGLSP-KSFDGRGNYNMGIREQIIFPEID-----YDQI DAIRGMNITITTT-----------------------AKTDEEGQALLRAFNFPFMSRIA-D--NPVSIPKGVEVT-L--- -S-G-DN-DIKVKGAKGSLAFAI--HP-L--IQVVQDG-ET--LRF----S-A--KSTKRVN-ALRGTTRALINNMVQGV SQGFERRLQLVGVGY--RAQLQG-RK--LVLS--LGYSHPVEFTA-P-E-GLTIEVP--S-PTEIIVKG-YDKQQVGQAA ANIRRFR------PPEPY---KGKGVRYADEVVVRKEAK----------MIQMQTSLEAADNSGARRLVCIKVLG-SQRR Y--AGIGDIIKVAVKEAIPR-G-------KVKKGEVYNALIVRTRKGVRRADGSLIRFDNNAVVLLN-NQLQ-PIGTRIF GPVTRELR-VENFMRIVSLAPEVLMR-L--NTISSAPGA-KQAEKRVG-RGIGSGW-GKTCGRGHKGQKSRSGGF-H--- -KVGF-E-GGQMPLQRRVPK-FG--FSSVRLDQLVDIAALVKA-RLIPVK---------VIA--SGK-L-D-K-P-VSL- QGIMVSAGARRAIEAAGGRI-K---QQK--GRN---RGQA-LRGSQIDFG----------EYGLKAI--GRGRITARQIE AARRAMTRHI------KRGGKIWIRIFPDKPITQKPLEVRQGKGK---------GGVEFWAANIQP-GRVLYEM--EG-- VPEGVARRAFELAAAKLPIKTVF-VKKTARLRRAAKTRHKI----HELGVVRLTVHRTPKHIYVQIIKP---A--DGNVV ASASTV-ESML-KQQL----KNT-GNKEAAITVGKTIAER--AKAKG-IAKVAFDRSGYKYH--GRVKALADAAREGGLQ F--------------------------------------------------------------MA-TTAILKNARLSAQK GRLVADQVRGLPVDKALDILGFS---------------------------------PKKASALIRKVLESAIAN----A- EHND-GADIDELRVAAIMVNEGPTIKRIRARARGRASRVFKRSCHIKVMVSEMRRVRVGDEVIVTAGR------SK-GKQ GKILRILGD-E--RVI--VQDVNMVKRHTR----PN-PTA-NKP-GGIIEREASIHISNVM-LYNPAT-------EK--G --DRIGFRR---LE--------DGKVR---YFKSND---EII--MGQKVHPTGIRLG--IV-KDWNSKWYA------DSG Q--FSELLNNDLAVRSYL--AKKLS-----HALVSNIQIDRPA-R-NARITIHTARPGIVIGKKGEDINNLRQEVSRMVH INIQEIRK---PELDATLVAANVAQQLERRIMFRRAMKRAVTNAMRV-GAQGIRIKVSGRLNGAEIARNEWYREGRVPL- -HTLRADIDYGFAEAKTTYGILGVKVWIFMSMTDPISDMLTRVRNGQNAGKVEVSM-PSSKLKVSIARVLKEEGYIEDCK VIA----D--------AKPTLVIRLKYY----GG-------K---PVIEDIHRASRPGLRMYKSRDKLPRIRGGLGIAIV STSRGVMTDKTARSIGEGGEVLCYVAAKQQIIRIRLKAFDHRLIDQSAREIVDTAKRTGAHVRGPIPLPTRKERFTILIS PHVNKDAR-DQYEIRTHKRLMDIVDPTEKTVDALMKLDLAAGVDVQIKLSHTVIGRVVSDKMDKTITVLIERKVAHSLYK KYVRRFTKLHAHDEN--NECRMGDIVAIAGTRPLSKTKAWKLVDILERA------------------------------- -MPRSI-KKGPFVDP-HLQKKVLEASA---SQSRR----PIKTWSRRSMVVPEMIGLTIAVHNGRQHVPILVTE-NMVGH KLGEFSPTRTFKGHV------A---NK----KSR-------- >GAMMA_Pasteurella_multocida_multocida_Pm70 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKIVNPE-LHKG------------KP-YAPLLDTKSKTGGRNNFGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-LDIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLSAGDTIQSGA-N-AP-IKVGNALPMR NIPVGSTVHNVELKPGKGGQIARSAGAYVQIIAR--EGNYVTLRLRSGEMRKVLAECTATIGEVGNSEHMLRVLGKAGAN -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-HNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGRKVGMTRIFN-EDGV---------SIPVTVIEIEANR VTQVK----TVE----T--DGY--SAIQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT--------TEGEEF-----TL---GQ-EINV--D-I-FADVKKVDVTGTSKGKGFAGGVKRW NFRT-QDATHGNSLSHRV-LGSIGQN-QTPG-RVFKGKKMAGHLGNERVTVQSLEVVRVDAERK---------------- ----------LLLVKGA-VPGATNGDVIVK--MELQVVG-A------NALTVSETTF----GR-EF-NEALIHQVVVAYA AGARQGSRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGD---IK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIKSILSELVRQD----------------R-LIVVEKF----EVE-A------ --PKTKLII--TASLD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VVVTVDAV KQIEAKLHDYYRDQV----VNELKDKFNYKSVMQVPRIEKITLNMGVG-EALTDKKLLDNAVADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGQALLAAFNFPFMSRVA-K--APVSIPAGVEVK-L--- -D-G--Q-LLTVKGKNGELSRTI--HN-A--VEVKQDN-NE--LTF----S-P--REGVGAD-AQAGTARALVNAMVIGV TEGFTKKLQLVGVGY--RAQIKG-NA--VALS--LGFSHPVEHAL-P-A-GITAECP--S-QTEIVLKG-ADKQLIGQVA ADIRAYR------RPEPY---KGKGVRYADEVVRIKEAK----------MIQEQTMLDVADNSGARSVMCIKVLG-SHRR Y--AAIGDIIKITVKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNTEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHSAKRLG-RGIGSGL-GKTGGRGHKGQKSRTGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLNDLVTLESLKAA-NVITVK---------IIL--AGE-V-K-G-A-VVV- RGLRVTKGAKAAIEAAGGSV-K---VHK--GRN---RGIA--AGTEVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VSEEIARNAFALAAAKLPIKTTF-VKKSARIRRAARARHMM----REQGVTRLVIHRTPRHIYAQVIAP---N--GSEVL AAASTV-EKVI-SEQV----KYT-GNKDAAAVVGKVVAER--ALAKG-VKDVAFDRSGFKYH--GRVQTLADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRYARTSAQK ARLVADLIRGKKVAAALEILTFT---------------------------------NKKAAALVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDAAKIRQNDEVIVLAGK------SK-GKR GKVTQVLPNGK---VI--VEGVNIITKHEK----PV--PALGKE-GGLVKKEAAIDVSNVA-IFNPKT-------NK--A --DRVGFRF----E--------DGKVR---FFKSNN---EII--MGQKVHPHGIRLG--IV-KPWSSTWFA------NTQ D--FADNLDGDFKVRKFL--NKELA-----NASVSRITIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRNAVAAIAQ INIAEVKK---PELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYNTAEAHTTYGVIGIKVWIFMSMQDPIADMLTRIRNGQAANKVAISM-PSSKLKVAIANVLAEEGYIESVK VLD--------G----VKPELEITLKYF----QG-------K---PVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRSVQGKVVSDKMDKSFVVAIERKVKHPLYG KFIRRTTKLHVHDEN--NEAKLGDIVEIKECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFLDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------K- >GAMMA_Photobacterium_profundum_SS9 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNSD-LHKG------------KP-YAPLLEKKSKSGGRNNNGRITVRH-IGGGNKQH---- YRLIDFK-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVSAGDMIQSGE-D-AA-IKVGNTLPMR NIPVGSTVHCVELKPGKGAQLARSAGAYAQIIAR--TGTYVTLRLRSGEMRKVLSECRATLGEVGNSEHMLRELGKAGAS -RWR-----GIR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRSR ---------------------------------MI---G-LIGRKVGMTRIFT-EEGI---------SIPVTVVEVEANR VTQVK----SLE----T--DGY--NAIQITT-------GT--KVSK----------PAAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GA-ELNV--E-L-FNEVKKVDVTGTSKGKGFQGVIKRW NFST-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGSIGGNVIVK--MELVVKG-A------DALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRSD--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----LW---- RTGGVTFAAR-P-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TGELD--E---NLFLAARNLYKVD-V---------------RDAATIDPVSLIAFDK----IVMTAAAV KQVEAKLHDYYKETV----VKELVEKFEYKSIMQVPRIEKITLNMGVG-EAINDKKLLENAAADMTAIAGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWDFFERLISIAVPRIRDFRGLNP-NSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTS-----------------------AASDEESKALLSAFNFPFMSRVA-K--APVVLLAGVEVK-L--- -N-G--Q-EITVKGPKGELALVA--HN-A--VVLTQEE-NT--ITF----G-P--REGDKAW-AQAGTVRALVNNMVVGV TEGFTKKLTLKGVGY--RANVAG-NT--VNLT--LGFSHPVAHEL-P-T-GVKAECP--S-QTEIVLTG-TDKQVIGQVA ADIRAYR------SPEPY---KGKGVRYADEVVRTKEAK----------MIQMQSTLDAADNSGARRVMCIKVLG-SHRR Y--AHIGDIIKITVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRQDGSVIRFDRNACVLLN-DTTEQPIGTRIF GPVTRELR-NTKFMKIVSLAPEVLMR-L--NTLSPAPGS-KPSAKRVG-RGIGSGL-GKTCGRGHKGQKSRSGGS-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLGELIDLATLKTA-NLITVK---------VVL--SGE-I-A-R-T-VTV- NGLRVTKGAKAAIEAAGGKI-K---TFK--GRN---RGLA--NGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRHV------KRQGQIWIRVFPDKPITSKPLEVRQGKGK---------GNVEYWVAQIQP-GKVLYEM--DG-- VPEVLAREAFNLAARKLPIKTTF-VKKASRIRRATRARRKI----AELGATRLVIHRTPRHVYAQVIAP---N--GSEVI AAASTV-EKVI-RESI----ANT-GNKDAAAAVGKAIAER--AIEKG-ISNVAFDRSGFQYH--GRVAALAEAAREAGLK F--------------------------------------------------------------ME-AIAKHRFARISPQK ARLVADQLRGKPVAQALEILNFS---------------------------------NKKAAELIKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADAAKIRRNDEVIVLTGK------DK-GKK GKITKVLAT-G--KVI--VEGINLVKKHQK----PV--PAMGVQ-GGIVEQEAAIDVSNVA-IFNAET-------GK--A --DRVGFRF----E--------DDKVR---FFKSNS---VTI--MGQKVHPNGIRLG--IV-KPWNTTWFA------NSQ E--FADNLDGDFKVRQFL--IKELK-----KASLSRVVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRAHISKIAQ INISEVRK---PELDAQLVGDSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTQYGVIGVKVWIFMSMQDPISDMLTRLRNGQTAKKVAVKM-PSSKQKVAIAALLKEEGFVAEFT VTG----D--------VKPELEVTLKYF---EAN-----------PVIEQIQRVSRPGLRIYKKKDALPSVMGGLGIAVV STSKGLMTDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVKGPIPLPTRKERFTVLTS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLTRIQLGRVISSKMDKSIVVAIERMVKHPMYG KYIKRTTKLHAHDEN--NECNLGDTVEVRECRPLSKTKSWTLVRIVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PVKTWSRRSMIIPQMIGLTIAVHNGRQHVPVFVSE-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Photorhabdus_luminescens_laumondii_TTO1 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKSSKTGGRNNNGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AS-IKTGNALPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVLSDCRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKRTDQ---FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEDNR VTQVK----ELD----N--DGY--RAIQVTT-------GS--KVNK----------PEAGHFK----------------- ---AG-VEAGRILREFRL--------SEGEEY-----AV---GQ-SISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDASHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGSTGGNLIVK--MELVMKD-AQ-----GALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TNEVD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VQKLMTQFGYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFLERLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFNFPFMSRVA-K--APVVIPTDVEVK-L--- -D-G--Q-VISIKGKNGELSRTI--HS-A--VEVKHAD-NQ--LTF----A-P--RDGVDGW-AQAGTTRSLMNAMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INMS--LGFSHPVDHEL-P-A-GITAECP--S-QTEIVLKG-ADKQVIGQVA AELRAYR------RPEPY---KGKGVRYADEVVRIKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AHVGDIIKVTIKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDGNACVLLN-NTSEQVIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPADGS-KHAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDFIDLNALKAA-NIVGAK---------VIL--SGE-I-N-R-A-VTV- RGLRVTKGAHAAIEAAGGKI-K---MHK--GRN---RGLA--AGADVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAI------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKAARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSETL VAASTT-EKAI-NEQL----KYT-GNKEAAAAVGKAIAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKQVLST-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKIR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWYA------NTK E--FADNLDSDFKVRQYL--KKELA-----KASISRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKTVAEIAQ INISEVRK---PELDAKLVADSITSQLERRIMFRRAMKRAVQNAMRQ-GAKGIKVEVSGRLGGAEIARPEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVLGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIAKVLKEEGYIEDYK IEG----D--------TKPELELVLKYF----QG-------K---AVVESIQRVSRPSLRIYKKKDELPQVMAGLGIAVV STSKGVMTDRAARQAGLGGEILCYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERKVKHPLYG KFIKRTTKLHVHDEN--NECGIGDVVEIRETRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Proteus_mirabilis_HI4320 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPATVERLEYDPNRSANIALVLYA-DGERRYILAPKGLKAGDKVQSGV-D-AA-IKTGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTIRLRSGEMRKIPSDCRATIGEVGNSEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-KNKRTEH---FIVHRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIENNR VTQVK----DLE----K--DGY--RAIQVTT-------GS--KVLK----------PEAGHFK----------------- ---AG-VEAGRLLREFRL--------NEGEEY-----TV---GQ-SISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-RVFKGKKMAGQLGNEQVTVQSLEVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVMKD-AQ-----GALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VS-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVSFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLIV--TAEVD--E---NLYLAARNLYKVD-V---------------RDAATIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VQKLMSQFGYHSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFNFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VITIKGKNGELTRTI--HN-A--VEIQHAD-NQ--LTF----A-P--RDGADAW-AQAGTTRSLLNAMVVGV TEGFTKKLQLVGVGY--RASVKG-NT--VNLS--VGYSHPVEHQL-P-A-GITAECP--T-QTEILLKG-ADKQVIGQVA AELRAYR------RPEPY---KGKGIRYADEVVRIKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--ADVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDSNACVLLN-NNSEQVIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLIDLNALKAA-NVVGAK---------LIL--SGE-V-N-R-A-VTI- RGLRVTKGARAAIESAGGKI-K---VHK--GRN---RGLA--IGTDVSFG----------TYGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEEVAREAFQLAAAKLPIKTTF-VKKAARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSETL VAASTT-EKAI-IEQL----KNT-GNKEAAAVVGKIVAER--ALEKG-IKSVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAIHRHARSSAQK VRLVADLIRGKKVSQALETLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRREDEVIVLTGK------DK-GKR GKVKQVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNK---ETI--MGQKVHPNGIRLG--IV-KPWNSTWYA------GTN E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKNVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVLGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANVLKEEGYIEDFK IEG----D--------TKPELEITLKYF----QG-------K---AVVESIQRVSRPSLRIYKRKDELPQVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSVVVAIDRMVKHPLYG KFIRRTTKLHVHDEN--NECGMGDVVEIRQTRPISKTKSWALVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PVKTWSRRSTIFPNMIGLTIAVHNGRQHVPVYVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Pseudoalteromonas_atlantica_T6c Concatenation of 2 sequences MPLLKAKPTSAGRRHVVQVVNPD-LHKG------------AP-YAPLLEKNSKSGGRNNNGRITVRH-VGGGHKQH---- YRVIDFK-R--NK-DGIPAKIERLEYDPNRSANICLVLYA-DGERRYILAPKGAKAGDQIQSGS-D-AA-IKAGNSLPMR NIPVGTTVHAIEMKPGKGAQIARSAGQYAQILAR--AEGYVTLRLRSGEVRRVLADCRATIGEIGNAEHMLRSLGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGKKTR-SNKR-TD-K-LIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEATPNR VTQLR----TDE----T--DGY--TALQVTA-------GD--KVNK----------AAAGHFK----------------- ---AG-VEAGRGLWEFRL------DGNEGEGI-----EV---GS-EITV--E-I-FAETKMVDVAGTSKGKGFQGAIKRW NFSH-QRNSHGNSLSHRA-PGSIGQN-QSPG-KVFKGKKMAGQMGNKRVTVQSLDVVRVDAENN---------------- ----------LLLVRGN-VPGAPGGDVIIK--MELVLKD-AQ-----SALEVSEATF----GR-EF-NEALVHQVVVAFG AGARQGSKAQKTRSE--------VR-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGAIQSILSELVRQE----------------R-LIVVEKF----SVE-A------ --PKTKLIV--TSEVD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFEK----VLITADAV KALEAKLHDFYKETV----VAELAKQFNYKSVMQVPRIEKITLNMGLG-EAVADKKVLENATADMQAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFFERLVSIAIPRIRDFRGLNP-KSFDGRGNYSMGVREQIIFPEID-----FDKV DKIRGMDITITTS-----------------------AETDAEAHALLSAFSFPFMSRIA-K--APVDVLSGVEVT-I--- -A-G--Q-EVTVKGKNGTLSRVF--ND-A--VEVVQEE-NQ--LKA----S-P--REGANGW-AQAGTARSLLDAMVIGV SQGFEKKLQLNGVGY--RAAAQG-KK--LNLT--LGFSHPVAYEM-P-E-GISVETP--S-QTEIVVKG-ADKQLVGQVA ANIRGYR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQMQTNLDVADNSGARRVQCIKVLG-SHRR Y--AHIGDIIKVTVKEAIPR-G-------KVKKGDVLTAVVVRTRKGVRRSDGSSIRFDNNAAVLLN-ANKQ-PIGTRIF GPVTRELR-VNN-MKIVSLAPEVLMH-L--NTLAPAPGA-KKSSKRVG-RGMGSGL-GKTGGRGHKGQKSRSGGS-V--- -KPGF-E-GGQMPIQRRLPK-FG--FTSVTLSEIVSLETLKAA-GLVKVK---------VLK--SGE-I-S-R-A-VTI- NGLKVTKGAREAIEAAGGKV-K---MHK--GRN---RGYA--AGDSVSFG----------TFGLKSV--GRGRMTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVCQIQP-GRVLYEM--EG-- VPESVAREAFELAASKLPFKTTF-VKKSARLRRATRARKKI----SELAAHRLVINRTPRHIYAQLIAP---C--GSQVL AAASTV-EADL-RTTV----KST-GNAEAAVAVGKAIAER--AIEKG-IKTVAFDRSGFKYH--GRVKALADAAREAGLQ F--------------------------------------------------------------ME-ALATHRHARTSAQK ARLVADQIRGLHVEKALELLAYS---------------------------------PKKSADLIKKVLESAIAN----A- EHNE-GADIDELTVSKVFVDEGPTMKRIKPRAKGRADRIFKRSSHITVVVADARKIRRDDEIIVLAGK------DK-GKL GKVLKVLPAAD--RLI--VEGVNLVKKHQK----PNPQL--GVT-GGVIEKEASIHVSNVA-IVNPKT-------GK--A --DRIGFRF---ED--------DKKVR---FFKSDG---ELV--MGQKVHPTGIRLG--IS-KPWTSTWYA------NTA D--YADNLFNDHQVRQYL--TKALK-----TASLSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRKHVSKLAQ INIAEVRK---PELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRI-GAKGIKVQVSGRLGGAEIARAEWYREGRVPL- -HTFRADIDYATSEANTTYGIIGVKVWIFMSMQDPIADMFTRVRNGQMASKVSVSM-PSSKLRVAIAAVLKEEGYVSDFA VSG----D--------VKPVLEVTLKYF----EG-------K---KVIESIERVSRPGLRIYKKKDELPKVLGGLGVAIV STSKGVMTDRAARKAGMGGEIIGYVAMPNQRIRIRLKAFDHKLIDQSTAEIVETAKRTGAQVSGPIPLPTRKERYTILTS PHVNKDAR-DQYEIRTHKRLVDIIEPTDKTVDALMRLDLAAGVDVQISLSRTVQGRVVSNKMDKTITVAVERKVKSPIYG KFIKRTTKLHAHDET--NQCNTGDVVTVRECRPMSKSKNWMLVDIVTKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEAAVE---KNDKK----PIKTWSRRSMIIPDMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudoalteromonas_haloplanktis_TAC125 Concatenation of 2 sequences MALQKCKPTSAGRRHLVKVVNSD-LHKG------------KP-YAPLLEKNSKSGGRNNNGRITVRH-IGGGHKQH---- YRLIDFK-R--TK-DGIPATVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLKAGDAIQSGV-D-AP-IKPGNALPMR NMPVGSTVHNVELKPGKGAQIARSAGAYVQILAR--DGQYVTLRLRSGEVRKVEADCRATLGEVGNAEHMLRSLGKAGAN -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGKPTKGAKTR-KNKR-TD-K-FIVRRR --------------------------------MAL---G-LVGRKVGMTRIFT-EDGV---------SIPVTVIEATPNR IAQIK----SEA----T--DGY--NALQVTA-------GT--KVNK----------ASAGHFK----------------- ---AG-VEAGRGLWEFRL-------NGGEGDF-----EV---GA-ELTV--E-L-FNEINKVDVTGTSKGKGFQGGVKRW NFSM-QDATHGNSLSHRA-PGSIGQN-QSPG-KVFKGKKMAGHMGAERVTTQNLELVRVDAERN---------------- ----------LLLVKGA-VPGAIGGDVIVK--MELAIKD-AS-----GGLEVSEATF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGKKPW---------AQKGTGRAR--------AGT---IR-SP----IW---- RSGGVSFAAK-P-QDHSQKVNRKMYRGAIKSILSELVRQE----------------R-LIVVESF----ALA-A------ --PKTKLIV--TEEVD--E---NLFLSARNLYKVD-T---------------RDVAGIDPVSLIAFDK----VLITAAAV KQLEAKLHEVYKDKV----VAELQEKFGFSSVMQVPLIEKITLNMGVG-EALADKKILDNAVADLAAISGQKPLITKARK SVAGFKVREGYPIGCKVTLRGERMWDFFERLVSIAIPRIRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGMDITITTS-----------------------AKSDEEGRALLEAFNFPFMSRIA-K--APISVPAGVEVT-L--- -K-G--Q-EITVKGKNGELTRTI--NN-A--VEVKVEE-NV--ITT----L-P--REGTDAW-AQAGTARALINNMIVGT HEGYEKKLQLVGVGY--RAAAKG-KT--LDLT--LGFSHPVHFAV-P-E-GITIETP--S-QTEVLVKG-VDKQLVGQTA ANIRAYR------KPEPY---KGKGVRYSDENVRRKEAK----------MIQMQTQLEVADNSGARKVQCIKVLG-SHRR Y--AAIGDIIKVSVKEAIPR-G-------KVKKGDVKNAVVVRTKKGVRRPDGSLIRFDSNAAVILN-DNLQ-PIGTRIF GPVTRELR-NDKFMKIVSLAPEVLMH-L--NTLSPAAGS-KTAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RVGF-E-GGQMPMQRRLPK-FG--FTSINLYEIVDLSALQAA-GLVKVK---------VVK--SGE-V-S-R-A-VTV- KGLRATKGAREAIEAAGGKV-K---THK--GRN---RGLA-QNGNKVSFG----------TFGLKAT--GRGRMTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITNKPLEVRMGKGK---------GSVEYWVAEIQP-GKVLYEM--EG-- VSEELAREAFDLAARKLPFKTTF-VKKTARLRRAKRTRRNY----IEQGTTRLVIHRTPRHIYAQVVTA------EGTVL AAASTV-EKAI-CETV----KGT-GNVAAAQAVGKAVAER--AADKG-IEKIAFDRSGFKYH--GRVKALADAAREAGLQ F--------------------------------------------------------------MQ-ALAKHKFASGSAQK ARLVADQIRGLPVDRALEILAYS---------------------------------PKKAAVLVKKVLESAIAN----A- EHNE-GADIDELRITTIFVDDGPTMKRIMPRAKGRADRILKRTSHITVMVSDAAKIRRDDEVIVLAGK------DK-GKR GKVLSVVTESG--RLF--VEGINLIKKHQK----PV-PQL-NQP-GGIVEKEASIDVSNVA-IYNSET-------SK--A --DRVGFKI----E--------DGKLR---IFKSTG---KTI--MGQKVHPTGIRLG--IS-KPWVSTWYA------SSK D--FSAQLFGDHKVRTFL--TKELK-----TASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRQAVTKIAQ INISEVRK---PELDAQLVADGIASQLERRVMFRRAMKRSVQNAMRI-GSKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSEALTTYGIIGVKVWIFMSLQDPIADLFTRIRNGQSAKKVSVTM-PNSKLKVAVAKVLKNEGYIADFA ING----D--------VKPELSIELKYF----EG-------K---AVIENIQRVSRPGLRIYKRRDELPKVMGGLGIAIV STSKGLMTDRAARSAGVGGEIIGFVAMSNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRFERFTVLTS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLIRTLQGRVISDKMEKSFTIAIARYVKHPIYG KFIRRTTKLHVHDEN--NEVQAGDVVTIRECAPISKSKSWTFVAVIERP----------------------------MRN SHATFS-QEGSFYRP-TLLKKVEKALE---SGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFITD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Pseudomonas_aeruginosa_PA7 Concatenation of 2 sequences MAIVKCKPTSAGRRFVVKVVNQE-LHKG------------AP-YAPLLEKKSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-R--NK-DGIPAIVERVEYDPNRTAHIALLKYA-DGERRYIIAPKGVAAGDQLISGI-G-AP-IKAGNSMPLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLVAR--EGAYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAT -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--AGRH-PVSP---WGLQTKGKKTR-SNKRTDN---MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEVEPNR VTQFK----TEE----T--DGY--RAVQVTA-------GE--RVTK----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------GEEQY-----AA---GD-QITV--D-L-FQAGQMVDVTGESKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHLGAERVTVQSLEIVRVDAERN---------------- ----------LLLVKGA-VPGATGGDVIVR--MQLNVNG-A------QAIEVSERTF----GG-EF-NETLVHQAVVAYM AGGRQGSKAQKTRSE--------VS-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGTTFAAK-P-RSHEQKLNKKMYRAALRSILAELVRLD----------------R-LVVVADF----AVD-A------ --PKTKLIV--TDGVD--E---NLYLAARNLAHVD-V---------------RDVQGSDPVSLIAYDK----VLVTVSAV KKFEARLKEIYRKEI----APKLKEELQLANVMEVPRVTKITLNMGLG-EAVGDKKIIENAVADLEKITGQKPIVTYARK SIAGFKIREGWPIGVKVTLRSDRMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARTDDEGRALLRAFKFPFMSRVA-K--NPVKLPAGVEIK-L--- -A-G--Q-QLSIKGAKGALELKV--HP-S--VEVIQDS-GE--LRF----A-A--RNGQQTR-AMAGTTRALVNNMVVGV SQGFERKLQLVGVGY--KAQAKG-QV--LSLS--LGFSHPVDYEL-P-A-GIVAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTKHGVRRTDGSIIRFDGNAAVLLN-SKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMQ-L--NDLRSAPGA-RREKHRPG-RGIGSGL-GKTGGRGHKGLTSRSGGK-V--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRTSELVSLQTLKDA-NLINVK---------VML--SGE-V-G-R-A-VTL- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-HRGSKVSFG----------EYALKAT--GRGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GGVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKETRLRRARKARLKM----RELETVRLCVYRSSQHIYAQVIAA---D--GGKVL ASASTL-DKDL-RE------GAT-GNIDAAKKVGQLVAER--AKAAG-VTQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEVIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGVNLIKRHTK----PN--PMLGQQ-GGIVEKEAPLHVSNVA-IFNTET-------SK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KPV--MGQKVHPNGIRLG--IV-KEHTSVWYA------DRK N--YADYLFADLKVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKTVVSM-PSSKLKAAVAKVLKDEGYIADFQ ISS----E--------VKPQLSIELKYF----EG-------K---PVIEEVKRISRPGLRQYKSVEQLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTVTVLIERRVKHPIYG KYVKRSTKLHAHDES--NQCRIGDLVTIRETRPLAKTKAWTLVDIVERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEVAVE---KNDRK----PIKTWSRRSMILPHMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAATRTYRGHA------A---DK----KAK------R- >GAMMA_Pseudomonas_aeruginosa_PAO1 Concatenation of 2 sequences MAIVKCKPTSAGRRFVVKVVNQE-LHKG------------AP-YAPLLEKKSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-R--NK-DGIPAIVERVEYDPNRTAHIALLKYA-DGERRYIIAPKGVAAGDQLISGI-G-AP-IKAGNSMPLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLVAR--EGAYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAT -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--AGRH-PVSP---WGLQTKGKKTR-SNKR-TD-N-MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEVEPNR VTQFK----TEE----T--DGY--RAVQVTA-------GE--RVTK----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------GEEQY-----AA---GD-QITV--D-L-FQAGQMVDVTGESKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHLGAERVTVQSLEIVRVDAERN---------------- ----------LLLVKGA-VPGATGGDVIVR--MQLNVNG-A------QAIEVSERTF----GG-EF-NETLVHQAVVAYM AGGRQGSKAQKTRSE--------VS-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGTTFAAK-P-RSHEQKLNKKMYRAALRSILAELVRLD----------------R-LVVVADF----AVD-A------ --PKTKLIV--TDGVD--E---NLYLAARNLAHVD-V---------------RDVQGSDPVSLIAYDK----VLVTVSAV KKFEARLKEIYRKEI----APKLKEELQLANVMEVPRVTKITLNMGLG-EAVGDKKIIENAVADLEKITGQKPVVTYARK SIAGFKIREGWPIGVKVTLRSDRMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARTDDEGRALLRAFKFPFMSRVA-K--NPVKLPAGVEIK-L--- -A-G--Q-QLSIKGAKGALELKV--HP-S--VEVIQDS-GE--LRF----A-A--RNGQQTR-AMAGTTRALVNNMVVGV SQGFERKLQLVGVGY--KAQAKG-QV--LSLS--LGFSHPVDYEL-P-A-GIVAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTKHGVRRTDGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMQ-L--NDLRSAPGA-RREKHRPG-RGIGSGL-GKTGGRGHKGLTSRSGGK-V--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRTSELVSLQTLKDA-NLINVK---------VML--SGE-V-G-R-A-VTL- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-HRGSKVSFG----------EYALKAT--SRGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GGVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKETRLRRARKARLKM----RELETVRLCVYRSSQHIYAQVIAA---D--GGKVL ASASTL-DKDL-RE------GAT-GNIDAAKKVGQLVAER--AKAAG-VTQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEVIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGVNLIKRHTK----PN--PMLGQQ-GGIVEKEAPLHVSNVA-IFNTET-------SK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KPV--MGQKVHPNGIRLG--IV-KEHTSVWYA------DRK N--YADYLFADLKVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKTVVSM-PSSKLKAAVAKVLKDEGYIADFQ ISS----E--------VKPQLSIELKYF----EG-------K---PVIEEVKRISRPGLRQYKSVEQLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTVTVLIERRVKHPIYG KYVKRSTKLHAHDES--NQCRIGDLVTIRETRPLAKTKAWTLVDIVERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEVAVE---KNDRK----PIKTWSRRSMILPHMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAATRTYRGHA------A---DK----KAK------R- >GAMMA_Pseudomonas_entomophila_L48 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNKE-LHKG------------AP-HAPLIEKKSKSGGRNNNGRITTRH-VGGGHKQH---- YRLVDFR-RN-DK-DGIPATVERIEYDPNRTAHIALLCYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKAGNSLQLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLIAR--EGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-N-MIVRRR --------------------------------MTI---G-VVGRKAGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------EEGDF-----QA---GD-LIKA--E-L-FTAGQLVDVTGQSKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLIKGA-VPGATGGDVVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGTKQQKTRSD--------VA-GGGKRPW---------RQKGTGRAR--------AGT---TR-GP----IW---- RGGGVTFAAR-P-QDHSQKLNKKMYRAALRSILAELVRSD----------------R-LVVVQDF----AVE-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYEK----VLITVSAV KKFEARLKEIYRNEI----APKLKEELKLSNVMEVPRVTKITLNMGLG-EAIGDKKVIEHAVADLEKITGQKPVVTFARK SIAGFKVREGWPIGVKVTLRRDKMYEFLDRLLAISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARSDDEGRALLRAFKFPFMSRVA-K--NPVKLPAGVEVK-F--- -A-G--Q-QLSVKGAKGTLELNV--HS-S--VEVTEEA-GE--LRF----S-A--RNGQQAR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-A-GITAETP--S-QTDILIKG-IDKQLVGQVA AEVRGFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-TKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQTSRSGGS-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELITVQSLKDA-NVIGVK---------IML--SGE-V-T-R-A-VTL- KGIAVTKGARAAIEAAGGKF-K---QMT--GHN---RGLA-LRGSKVSFG----------EFALKAV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GSVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKVTRLRRARKARLKM----HELEAVRLCVFRSSQHIYAQVISA---D--GSKVL ASASTL-DKEL-RD------GAT-GNIDAATKVGKLVAER--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--IGGVNLVKRHTK----PN--PMAGVQ-GGIVEKEAPLHASNVA-IFNGET-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAV--MGQKVHPTGIRLG--IV-KEHTSVWYA------DGA T--YADYLLKDLQTREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSTLKVAVAKVLKDEGYIAGYE VTG----E--------AKPSLSIELKYF----EG-------R---PVIEELKRSSRPGLRQYKAVSELPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDES--NQCKIGDKVSIRETRPLAKTKSWALVEVLERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEVAVE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudomonas_fluorescens_Pf-5 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNQE-LHKG------------AP-HAPLLEKKSKSGGRNNNGRITTRH-VGGGHKQH---- YRLVDFR-RN-DK-DGIAATVERIEYDPNRTAHIALLLYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKPGNALQLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLVAR--EGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-K-MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------EEGEY-----QA---GD-LINA--E-I-FAAGQLVDVTGQSKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGSKQQKTRSD--------VS-GGGKRPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGTTFAAR-P-QDHSQKLNKKMYRAAMRSILAELVRTD----------------R-LVVVQDF----AVE-T------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYDK----VLITVSAV KKFEARLKEIYRKEI----APKLKEELKLSNVMEVPRVTKITLNMGLG-EAIGDKKVIEHAVADLEKITGQKVVVTYARK SIAGFKVREGWPIGVKVTLRRERMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------AKNDDEGRALLRAFKFPFMSRVA-K--NPVKLPAGVEVK-F--- -A-G--Q-QLSVKGAKGTLELNV--HS-S--VEIVQEA-GE--LRF----A-A--RNGQQTR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-E-GITAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-NEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQTSRSGGT-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELVTVQSLKDA-NVINVK---------IML--SGE-V-T-R-A-VTI- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-LRGSKVSFG----------EFALKSV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPISKKPLEVRMGKGK---------GNVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKVTRLRRARKARLKM----HELEVVRLCVFRSSQHIYAQVISA---D--GNKVL ASASTL-DKEL-RD------GAT-GNIDAATKVGQLVATR--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREAGLE F-------------------------------------------------------------MME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGLNLVKRHTK----PN--PMSGVQ-GGIVEKEAPLHASNVA-IFNSET-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAV--MGQKVHPIGIRLG--IV-KEHTSVWYA------DGR T--YADYLLADLNVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSTLKVAVAKVLKDEGYIAGYQ ISS----E--------IKPLLSIELKYF----EG-------R---PVIEEVKRVSRPGLRQYKSVEELPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDET--NQCHIGDKVTIRETRPMAKTKSWALVDVLERA------------------------------- -MPRSL-KKGPFIDL-HLLKKIEVAAE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudomonas_fluorescens_SBW25 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNQE-LHKG------------AP-HAPLLEKKSKTGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-RN-DK-DGISATVERIEYDPNRTAHIALLLYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKPGNALQLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLIAR--EGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-K-MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRTVMEFRL---------EDGDY-----QA---GD-LINA--E-I-FAAGQLVDVTGQSKGKGFQGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGSKQQKTRSD--------VR-GGGKRPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGTTFAAR-P-QDHSQKLNKKMYRAALRSILAELVRTD----------------R-LVVVQDF----AVE-S------ --PKTKLIV--SEAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYDK----VLITVSAV KKFEARLKEIYWKEI----APKLKEELKLSNVMEVPRVTKITLNMGLG-EAVGDKKVIEHAVADLEKITGQKVVVTYARK SIAGFKVREGWPIGVKVTLRRERMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------AKNDDEGRALLRAFKFPFMSRVA-K--NPVKLPAGVEVK-F--- -A-G--Q-QLSVKGAKGTLELNI--HS-S--VEIVEEA-GE--LRF----A-A--RNGQQTR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-E-GITAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQTSRSGGT-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELVTVQTLKDA-NVINVK---------IML--SGE-V-T-R-A-VTIG KGIGATKGARSAIEAAGGKF-K---QMT--GHN---RGLA-QRGSKVSFG----------EFALKSV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPISKKPLEVRMGKGK---------GNVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKVTRLRRARKARLKM----HELEVVRLCVYRSSQHIYAQVISA---D--GNKVL ASASTL-DKEL-RD------GAT-GNIDAATKVGQLVATR--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREAGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAN-N--RLV--IGGLNLVKRHTK----PN--PMSGVQ-GGIVEKEAPLDASNVA-IFNGET-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAV--MGQKVHPIGIRLG--IV-KEHTSVWYA------DGR T--YADYLFADLKVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYANYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSKLKVAVAKVLKDEGYIAGYQ ISS----E--------TKPLLSIELKYF----EG-------R---SVIEEVKRVSRPGLRQYKSAEDLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDET--NQCHIGDKVTIRETRPLAKTKSWALVDVLERA------------------------------- -MPRSL-KKGPFIDL-HLLKKIEVAAE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRLHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudomonas_mendocina_ymp Concatenation of 2 sequences MAIVKCKPTSAGRRFVVKVVNQE-LHKG------------AP-YAPLLEKKSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-RN-DK-DGIPATVERVEYDPNRTAHIALLKYA-DGERRYIIAPKGVVAGDQLVAGN-M-AP-IKPGNSLQLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLIAR--EGAYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-ANKR-TD-N-MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----NEE----S--DGY--RAVQVTV-------GE--RVSK----------AQAGHFK----------------- ---AN-VAAGRTVMEFRL---------EEGDY-----QA---GD-LINA--E-I-FQAGQLVDVTGQSKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLVKGA-VPGATGGDVIVR--MQLNVNG-A------QAIEVSDATF----GG-EF-NETLVHQAVVAYM AGGRQGTKGQKSRSD--------VS-GGGKRPW---------RQKGTGRAR--------AGT---TR-GP----IW---- RGGGVTFAAS-T-RNHDQKLNKKMYRAALRSILAELVRTD----------------R-LVVVEDF----AVE-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYEK----VLVTVSAV KKFEARLKEIYRKEI----APKLKEELKLANVMEVPRITKITLNMGLG-EAIGDKKVIENAVADLEKITGQKVVVTHARK SIAGFKVREGWPIGVKVTLRRERMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARNDDEGRALLRAFNFPFMSRVA-K--NPVVLPAGVEVK-L--- -A-G--Q-QLSVKGAKGALELNV--HS-S--VEVIQEG-SE--LRF----A-A--RNGQQNK-AMAGTTRALVNNMVIGV SQGFERKLQLVGVGY--KAQAKG-QV--LNLA--LGFSHPIDYEL-P-A-GVVAETP--N-QTEILIKG-IDKQLVGQVA AEIRDFR------RPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLMQ-L--NDLRSAPGA-RREKHRPG-RGIGSGL-GKTGGRGHKGQTSRSGGS-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRTSELVTLQALKDA-NLVGVK---------VML--SGE-V-T-R-A-VTL- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-QRGSKVSFG----------EFALKSV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GGVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATTF-VKKVTRLRRARKARLKM----HELEAVRLCVYRSSQHIYAQVISA---D--GSKVL ASASTL-DKAL-RD------GAT-GNVDAAKKVGQLVAER--AKAAG-VTQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGINLVKRHTK----PN--PMSGVQ-GGIVEKEAPLHASNVA-IFNSET-------NK--A --DRVGFKI----E--------DGKIR---VFKSTQ---KPV--MGQKVHPVGIRLG--IV-KDHTSVWYA------DGR N--YADYLNADLKVRAYL--QDKLK-----SASVSRIDIARPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSTLKVAVAKVLKDEGYIAGYE VNG----E--------AKPQLSIELKYF----EG-------R---PVIEEVKRVSRPGLRQYKSVDDLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDES--NQCKIGDKVSIRETRPQSKTKSWALVEVVERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEAAVE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KGK------R- >GAMMA_Pseudomonas_putida_F1 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNKE-LHKG------------AP-HAPLIEKKSKSGGRNNNGRITTRH-VGGGHKQH---- YRLVDFR-RN-DK-DGIPATVERIEYDPNRTAHIALLCYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKAGNSLQLR NIPVGSTIHGIELKPGKGAQIARSAGASAQLIAR--EGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-N-MIVRRR --------------------------------MTI---G-VIGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------EEGDF-----QA---GD-LIKA--E-L-FTAGQLVDVTGQSKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLIKGA-VPGATGGDVVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGTKQQKTRSD--------VA-GGGKRPW---------RQKGTGRAR--------AGT---TR-GP----IW---- RGGGVTFAAR-P-QDHSQKLNKKMYRAALRSILAELVRSD----------------R-LVVVQDF----AVE-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYEK----VLITVSAV KKFEARLKEIYRNEI----APKLKEELKLSNVMEVPRVTKITLNMGLG-EAIGDKKVIEHAVADLEKITGQKPVVTFARK SIAGFKVREGWPIGVKVTLRSDKMYEFLDRLLAISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARSDDEGRALLRAFKFPFMSRVA-K--NPVKLPSGVEVK-F--- -A-G--Q-QLSVKGAKGTLELNV--HS-S--VEVTEES-GE--LRF----V-A--RNGQQAR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-A-GITAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQTSRSGGS-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELISVQSLKDA-NVINVK---------IML--SGE-V-T-R-A-VTI- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-LRGSKVSFG----------EFALKAV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPISKKPLEVRMGKGK---------GSVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKVIRLRRARKARLKM----HELEVVRLCVFRSSQHIYAQVISA---D--GSKVL ASASTL-DKDL-RD------GAT-GNIDAATKVGKLVAER--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--IGGVNLVKRHTK----PN--PMAGVQ-GGIVEKEAPLHASNVA-IFNGET-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAV--MGQKVHPTGIRLG--IV-KEHTSVWYA------DGA T--YADYLLKDLKTREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSTLKVAVAKVLKDEGYIAGYQ VTG----E--------AKPSLSIELKYF----EG-------R---PVIEELKRSSRPGLRQYKAVTDLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDEA--NQCKIGDKVSIRETRPLAKTKSWALVEVLERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEVAVE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudomonas_putida_KT2440 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNKE-LHKG------------AP-HAPLIEKKSKSGGRNNNGRITTRH-VGGGHKQH---- YRLVDFR-RN-DK-DGIPATVERIEYDPNRTAHIALLCYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKAGNSLQLR NIPVGSTIHGIELKPGKGAQIARSAGASAQLIAR--EGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-N-MIVRRR --------------------------------MTI---G-VIGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------EEGDF-----QA---GD-LIKA--E-L-FTAGQLVDVTGQSKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLIKGA-VPGATGGDVVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGTKQQKTRSD--------VA-GGGKRPW---------RQKGTGRAR--------AGT---TR-GP----IW---- RGGGVTFAAR-P-QDHSQKLNKKMYRAALRSILAELVRSD----------------R-LVVVQDF----AVE-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYEK----VLITVSAV KKFEARLKEIYRNEI----APKLKEELKLSNVMEVPRVTKITLNMGLG-EAIGDKKVIEHAVADLEKITGQKPVVTFARK SIAGFKVREGWPIGVKVTLRSDKMYEFLDRLLAISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARSDDEGRALLRAFKFPFMSRVA-K--NPVKLPSGVEVK-F--- -A-G--Q-QLSVKGAKGTLELNV--HS-S--VEVTEES-GE--LRF----V-A--RNGQQAR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-A-GITAETP--S-QTDILIKG-IDKQLVGQVA AEIRDFR------PPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQTSRSGGS-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELISVQSLKDA-NVINVK---------IML--SGE-V-T-R-A-VTI- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-LRGSKVSFG----------EFALKAV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPISKKPLEVRMGKGK---------GSVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-VKKVIRLRRARKARLKM----HELEVVRLCVFRSSQHIYAQVISA---D--GSKVL ASASTL-DKDL-RD------GAT-GNIDAATKVGKLVAER--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--IGGVNLVKRHTK----PN--PMAGVQ-GGIVEKEAPLHASNVA-IFNGET-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAVQ-MGQKVHPTGIRLG--IV-KEHTSVWYA------DGA T--YADYLLKDLKTREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSTLKVAVAKVLKDEGYIAGYQ VTG----E--------AKPSLSIELKYF----EG-------R---PVIEELKRSSRPGLRQYKAVTDLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDEA--NQCKIGDKVSIRETRPLAKTKSWALVEVLERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEVAVE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudomonas_stutzeri_A1501 Concatenation of 2 sequences MAIVKCKPTSAGRRFVVKVVNQE-LHKG------------AP-YAPLLEKKSKTGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-R--NK-DGIPAIVERIEYDPNRTAHIALLKYA-DGERRYIIAPKGVSAGDQLVSGI-N-AP-IKAGNSLPLR NIPLGSTVHGIELKPGKGAQLVRSAGASAQLVAR--EGSYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAK -RWK-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGFPTKGAKTR-TNKRTDN---MIVRRR --------------------------------MTI---G-VVGRKCGMTRVFT-EDGV---------SIPVTVIEIEPNR VTQFK----NEE----S--DGY--RAVQVTV-------GE--RVTK----------AQAGHFK----------------- ---AN-VAAGRGVWEFRL---------EGEEF-----QV---GD-QINA--E-I-FQAGQLVDVTGQSKGKGFAGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEIVRVDAERN---------------- ----------LLLVKGA-VPGATGGDVFVR--MQLNVNG-A------QAIEVSDRTF----GG-EF-NETLVHQAVVAYM AGGRQGSKQQKTRSD--------VS-GGGKRPW---------RQKGTGRAR--------AGT---TR-GP----IW---- RGGGVTFAAR-P-QNHEQKLNKKMYRAALRSILAELVRSE----------------R-LVVVEDF----AVD-A------ --PKTKLIV---SDAD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYDK----VLITVSAV KKFEARLKEVYRKEI----APKLKEELQLKNVMEVPRITKITLNMGIG-EAIGDKKIIDNAVADLEKITGQKVVVTHARK SIAGFKVREGWPIGVKVTLRSDRMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------ARTDDEGRALLRAFNFPFMSRVA-K--NPVKLPAGVEIK-M--- -S-G--Q-QLSVKGAKGALELNV--HP-S--VEVIQEG-GE--LRF----A-G--RNGQQTR-AMAGTTRALVNNMVIGV SQGFERKLQLVGVGY--KAQAKG-QV--LSLA--LGFSHPVDYEL-P-Q-GVTAETP--S-QTDILIKG-VDKQLVGQVA AEIRDFR------RPEPY---KGKGVRYSDEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRPDGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMQ-L--NDLRSAPGA-RREKLRPG-RGIGSGL-GKTGGRGHKGQTSRSGGK-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRTSELVTVQSLKDA-NVINVK---------VML--SGE-V-G-R-A-VTL- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-QRGSKVSFG----------EFALKSV--SRGRLTARQIE AARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GSVEYWVAQIQP-GKVLYEI--EG-- VSEELAREAFALAAAKLPLATSF-V---------------M----RELEAVRLCVHRSSQHIYAQVLSA---D--GGKVL ASASTL-DKEL-RD------GAT-GNVDAAKKVGQLVAER--AKAAG-VTQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGDALNLLAFS---------------------------------SKKAAEIMKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRNDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGINLVKRHTK----PN--PMSGVQ-GGIVEKEAPLHVSNVA-IFNGET-------NK--A --DRVGFKV----E--------EGKIR---VFKSTQ---KPV--MGQKVHPTGIRLG--IV-KEHTSVWYA------DGR T--YADYLLADLNVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKSVVSM-PSSTLKVAVANVLQGEGYIAGYQ VSG----D--------VKPQLSIELKYF----EG-------R---PVIEELKRVSRPGLRQYKSVDQLPKVRGGLGVSIV STNKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDET--NQCKIGDKVSIRETRPQSKTKSWALVEVVERA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEAAVE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVSE-DMVGH KLGEFAATRTYRGHV------A---DK----KGK------R- >GAMMA_Pseudomonas_syringae_pv_phaseolicola_1448A Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNQE-LHKG------------AP-HAPLLEKKSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-RN-DK-DGIAATVERIEYDPNRTAHIALLLYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKPGNALQLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLIAR--EGVYVTLRLRSGEMRKVLSECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-K-MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRTVMEFRL---------EEGDY-----QA---GD-QINA--E-I-FAAGQLVDVTGQSKGKGFQGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLELVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGSKQQKTRSD--------VR-GGGKRPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGTTFAAR-P-QDHTQKLNKKMYRAALRSILAELVRTD----------------R-LVVVQDF----AVE-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYDK----VLITVSAV KKFEARLKEIYRKEI----APKLKEELKLSNVMEVPRVTKITLNMGLG-EAIGDKKVIEHAVADLEKITGQKVVVTYARK SIAGFKVREGWPIGVKVTLRRDRMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------AKNDDEGRALLRAFKFPFMSRVA-K--NPVKLPSGVEVK-L--- -V-G--Q-LLSVKGPKGTLELII--HS-SVEVEIVEEA-GE--LRF----A-A--RNGQQTR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-N-GITAETP--S-QTDILIRG-IDKQLVGQVA AEIRDFR------RPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQSSRSGGT-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELVTVQSLKDA-NVINVK---------IML--SGE-V-T-R-A-VTI- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-LRGSKVSFG----------EFALKSV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GNVEYWVAQIQP-GKVLYEI--EG-- VTEELAREAFALAAAKLPLATSF-VKKVTRLRRARKARLKM----HELEVVRLCVHRSSQHIYAQVISA---D--GSKVL ASASTL-DKEL-RD------GAT-GNIDAATKVGKLVAER--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEILKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGINLVKRHTK----PN--PMSGVQ-GGIVEKEAPLHASNVA-IFNGAT-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAV--MGQKVHPIGIRLG--IV-KEHTSVWYA------DGR T--YADYLFADLKVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYANYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKPVVSM-PSSTLKVAVAKVLKDEGYIAGYQ ISS----E--------VKSSLSIELKYF----EG-------R---PVIEEVKRVSRPGLRQYKSSDDLPKVRGGLGVSIV STSKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTEKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDET--NQCHIGDKVTIRETRPVAKTKSWALVDILERA------------------------------- -MPRSL-KKGPFIDL-HLLKKIEVAAE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Pseudomonas_syringae_pv_tomato_DC3000 Concatenation of 2 sequences MAIVKCKPTSPGRRFVVKVVNQE-LHKG------------AP-HAPLLEKKSKTGGRNNNGRITTRH-IGGGHKQH---- YRLVDFR-RN-DK-DGITATVERIEYDPNRTAHIALLLYA-DGERRYIIAPKGVSAGDQLIAGA-L-AP-IKPGNALQLR NIPVGSTVHGIELKPGKGAQIARSAGASAQLIAR--EGVYVTLRLRSGEMRKVLSECRATLGEVSNSEHSLRSLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-HPVSP---WGFPTKGAKTR-GNKR-TD-K-MIVRRR --------------------------------MTI---G-VVGRKCGMTRIFT-EEGV---------SIPVTVIEIEPNR VTQFK----TEE----T--DGY--RAVQVTV-------GE--RVTA----------AQAGHFK----------------- ---AN-VAAGRTVMEFRL---------EEGEY-----QA---GD-QINA--E-I-FAAGQLVDVTGQSKGKGFQGTIKRW NFRG-QDNTHGNSVSHRV-PGSIGQC-QTPG-RVFKGKKMSGHMGAERVTVQSLEVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLVVR--MQLNVND-A------QAIEVSELTF----GG-EF-NETLVHQAVVAYM AGGRQGSKQQKTRSD--------VR-GGGKRPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGTTFAAR-P-QDHTQKLNKKMYRAALRSILAELVRTD----------------R-LVVVQDF----AVE-A------ --PKTKLIV--SDAVD--Q---NLYLAARNLPHVD-V---------------RDVQGSDPVSLIAYDK----VLITVSAV KKFEARLKEIYRKEI----APKLKEELKLGNVMEVPRVTKITLNMGLG-EAIGDKKVIENAVADLEKITGQKVVVTYARK SIAGFKVREGWPIGVKVTLRRDRMYEFLDRLLSISLPRVRDFRGLNA-KSFDGRGNYSMGVKEQIIFPEID-----YDKI DALRGLDITLTTT-----------------------AKNDDEGRALLRAFKFPFMSRVA-K--NPVKLPSGVEVK-L--- -V-G--Q-QLSVKGAKGTLELII--HS-S--VEIVEEA-GE--LRF----A-A--RNGQQTR-AMAGTTRALVNNMVQGV SQGFERKLQLVGVGY--KAQAKG-TV--LNLA--LGFSHPVDYEL-P-N-GITAETP--S-QTDILIRG-IDKQLVGQVA AEIRDFR------RPEPY---KGKGVRYADEVVRRKEAK----------MIQTQSMLDVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKVTVKEAIPR-G-------KVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-TEKFMKIVSLAPEVLMK-L--NDLSPAPGS-RREKHRPG-RGIGSGL-GKTGGRGHKGQSSRSGGT-I--- -APGF-E-GGQQPLHRRLPK-FG--FVSVRLSELVTVQSLKDA-NVINVK---------IML--SGE-V-T-R-A-VTI- KGIAATKGARAAIEAAGGKF-K---QMT--GHN---RGLA-LRGSKVSFG----------EFALKSV--ARGRLTARQIE SARRALTRHV------KRGGKIWIRVFPDKPVTKKPLEVRMGKGK---------GNVEYWVAQIQP-GKVLYEI--EG-- VTEELAREAFALAAAKLPLATSF-VKKVTRLRRARKARLKM----HELEVVRLCVHRSSQHIYAQVISA---D--GSKVL ASASTL-DKEL-RD------GAT-GNIDAATKVGKLVAER--AKAAG-VSQVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLSGARISAQK ARLVADQIRGKKVGEALNLLAFS---------------------------------SKKAAEILKKVLESAVAN----A- EHNE-GADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADMQKIRRDDEIIVIAGK------DK-GKR GKVLKVLAD-D--RLV--VGGINLVKRHTK----PN--PMSGVQ-GGIVEKEAPLHASNVA-IFNGAT-------NK--A --DRVGFKV----E--------DGKIR---VFKSTQ---KAV--MGQKVHPIGIRLG--IV-KEHTSVWYA------DGR T--YADYLFADLKVREYL--QDKLK-----SASVSRIDIHRPA-Q-TARITIHTARPGIVIGKKGEDVEKLRQDLTKQVH INIEEIRK---PELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRI-GAKGIKIQVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYANYEAHTTYGVIGVKVWIFMSMQDPLADMLTRIRNAQMAEKPVVSM-PSSTLKVAVAKVLKDEGYIAGYQ ISS----E--------VKSSLSIELKYF----EG-------R---PVIEEVKRVSRPGLRQYKSSDDLPKVRGGLGVSIV STSKGVMTDRAARAAGVGGEVLCTVFMQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRVLDIVQPTEKTVDALMKLDLAAGVEVQISLVRTLTGRVVSDKMDKTITVLIERRVKHPIYG KYVKRSTKLHAHDET--NQCHIGDKVTIRETRPVAKTKSWALVDILERA------------------------------- -MPRSL-KKGPFIDL-HLLKKIEVAAE---KNDRK----PVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVSE-DMVGH KLGEFAGTRTYRGHV------A---DK----KAK------R- >GAMMA_Psychrobacter_arcticus_273-4 Concatenation of 2 sequences MPIVRAKPTSPGRRFVEKVVHPH-LYKG------------RP-FAALLESKSKTGGRNNNGRITTRH-IGGGHKQH---- YRIIDFK-R--TK-DNIPATVERIEYDPNRTAHIALLKYA-DGERRYIIAAKKQAVGDTVMSGE-L-SP-IRPGNCLPLK NIPLGTVIHNIELKIGKGAQMARAAGASVQLLGR--DGIYAILRLRSGETRRVHVNCRAVIGEVSNTENNLKSLGKAGAS -RWR-----GIR-P-SVRGVAMNPVDHPHGGGEGRN----KGRH-PTSP---WGQKSKGLKTR-NNKRTDS---MIIRRR --------------------------------MAI---G-LVGKKCGMTRVFT-EAGA---------SIPVTVVEISANR ITQVK----NTD----V--DGY--QAIQVTT-------GT--RVTA----------AQKGHFK----------------- ---AG-VAAGRGVWEFRA------NDSDLEGR-----EI---GG-EILA--D-L-FEQGQMVDVTGSSKGKGFQGPVKRH NFSM-QDATHGNSVSHRA-HGSTGQN-QSPG-KVFKGKKMAGQMGNKRVTVQGLEVISVDAEKG---------------- ----------LLVIKGA-IPGATGGDVIVR-MDLKTVTG--------AAVELSDTAF----GR-EF-NEALVHQVVTAYL AGARQGTRAQKTRAE--------VS-GGGIKPW---------RQKGTGRAR--------AGS---IR-SP----IW---- RGGGRAFAAK-P-QDWSQKVNRKMYRGAMQCILAELIRQE----------------R-LILVEEI----SVS-G------ --PKTKLIV--TKEVD--E---NLYLAARNIPHVN-V---------------LDTSEVDPVSLIAFDK----VIMSVEAA KQFEARLKSLYNEEL----KQQIKEELGLANVMQVPKITKITLNMGVG-GASQDKKLLEGAVADMTAIAGQKPVVTKARK SVAGFKIREEWPIGCKVTLRGEQMYEFLDRLVAIAIPRIRDFRGFSP-KAFDGRGNYSLGIKEQIVFPEVD-----FDKI DRIRGMDVTITTS-----------------------AQSDEEGRALLKAFGFPFMSRVA-K--APVTLPNGVSVT-L--- -N-D--R-QVEVKGKNGNMSLRL--HE-L--VELKQED-DL--IIF----S-P-TVDSKEAM-MHAGTMRSLLNNLVIGV NEGFEKRLLLIGVGY--RAQATG-NK--VTLN--VGYSHPVEYTL-P-E-GVSAETP--T-QTEIVLKS-NDKQQLGQAA ANIRGFR------PPEPY---KGKGIRYSDEHVIRKEAK----------MIQVESMLEVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIKVTVKEAIPR-G-------RVKKGDVMNAVVVRTKKGVRRPDGSVLRFDDNAAVLLN-QNKA-PIATRIF GPVTRELR-GDQFMKIVSLAPEVLLR-L--NELSPGVGA-KKTAQRRG-RGIGSGL-GKTGGRGVKGQKSRSGSS-V--- -RSGF-E-GGQTPLYRRLPK-FG--FTSVRLSELVSIETLKAA-NLIRAR---------VML--SGE-V-T-K-A-YTF- KGIKVTKGAKQAIEAAGGSI-K---MHK--GRN---TGLA-HRGSTVAFG----------QIGLKSL--TRGRMTARQIE AARRTITRKI------KRGGKIWIRVFPDKPITNKPLEVRMGKGK---------GPVEYWVCEIKP-GKILYEL--EG-- ISEELAREALTLAASKLPFKTTI-VKKAARLRRAKKTRAHI----RFLGVHRLTVNRTPRHIYAQIISP---N--GGEVI AQASTL-DSSL-RS------GAT-GNADAATSVGQMIAER--AKAAG-ITKVAFDRSGFKYH--GRVKALAEAARENGLE F--------------------------------------------------------------ME-VTAKLRGAAISAQK VRLVADEVRGKSIERALDILTYS---------------------------------NKKGAVFVKKCLNSAIAN----A- ENNN-GLDIDTLKVSTIYVDEGITLKRILPRAKGRADRISKRTCHITIKVGEMSKLRKGDTVIVIAGK------DK-GKQ GTVQAVKNDRI--K----VEGINIVTKHQK----PN--QATGVE-GGILKQEAFLHISNVA-ILNAQT-------QK--A --DRITYQF---GE--------DGKQR---VYRSNG---EVV--MGQKVHPIGIRLG--VV-KKHNANWYA------SPK Q--YSEYLINDIQVREYL--RKKLD-----SAMISKIMIERPT-G-AAKITIATARPGIVIGKKGEDIERLQKELTKMAQ VNIEEITS---PDLDAHLVAEGIASQLERRVMFRRAMKRAVQNSMRS-GAKGIKVELSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYSSVRAETTYGTIGVKVWIFMSMQDTVGDMLTRIRNAQMANKVSVAM-PSSKLRKSIADLLVNEGYVASAV VTE----E--NN----NKATLTIVLKYF----EG-------K---AVIETIQRFSRPGLRQHRGKDAIPTVKQGMGVAIV STSQGIMSDRAARAAGIGGEIVAFVAMANQRIRIRLKSFDHRLIDQSAQEIVDTAKRTGAQVCGPVPLPTRIERFNVLTS PHVNKDAR-DQYEIRTHKRMVDIVQPTDKTVDALMKLDLAAGVDVQIALASVLTGRVVSDKMDKSITVLIERLVRHPLYG KQLRRSTKIKAHDEN--NVCQQGDLVRIKETRPISKTKSWTLVDVVEKV------------------------------- -MPRSL-KKGPFIDA-HLFAKVETALE---TNSRK----PIKTWSRRSMILPQMVGLTLSVHNGRTHVPVIVSE-QMVGH KLGEFAPTRTYRGHG------I---DK----KAK------R- >GAMMA_Psychrobacter_cryohalolentis_K5 Concatenation of 2 sequences MPIVRAKPTSPGRRFVEKVVHPH-LYKG------------RP-FAALLESKSKTGGRNNNGRITTRH-IGGGHKQH---- YRIIDFK-R--TK-DNIPATVERIEYDPNRTAHIALLKYA-DGERRYIIAAKKQAVGDTVMSGE-L-SP-IRPGNCLPLK NIPLGTVIHNIELKIGKGAQMARAAGASVQLLGR--DGIYAILRLRSGETRRVHVNCRAVIGEVSNTENNLKSLGKAGAS -RWR-----GIR-P-SVRGVAMNPVDHPHGGGEGRN----KGRH-PTSP---WGQKSKGLKTR-HNKR-TD-N-MIIRRR --------------------------------MAI---G-LVGKKCGMTRVFT-EAGA---------SIPVTVVEISANR ITQVK----NTD----V--DGY--QAIQVTT-------GT--RVTA----------AQKGHFK----------------- ---AG-VAAGRGVWEFRA------NDSDLEGR-----EI---GG-EILA--D-L-FEQGQMVDVTGNSKGKGFQGGVKRH NFSM-QDATHGNSVSHRA-IGSTGQN-QSPG-KVFKGKKMPGQMGNKRVTVQGLEVISVDVENG---------------- ----------LLVIKGA-IPGATGGDVIVR-MDLKTVTG--------AAVELSDTAF----GR-EF-NEALVHQVVTAYL AGARQGTRAQKTRAE--------VS-GGGIKPW---------RQKGTGRAR--------AGS---IR-SP----IW---- RGGGRAFAAK-P-QDWSQKVNRKMYRGAMQCILAELIRQE----------------R-LILVEEI----SVS-G------ --PKTKLIV--TKEVD--E---NLYLAARNIPHVN-V---------------LDTSEVDPVSLIAFDK----VIMTVEAA KQFEARLKSLYNEEL----KQQIKEELGLANVMQVPKITKITLNMGVG-GASQDKKLLEGAVADMTAIAGQKPVVTKARK SVAGFKIREEWPIGCKVTLRGEQMYEFLDRLIAIAIPRIRDFRGFSP-KAFDGRGNYSLGIKEQIVFPEVD-----FDKI DRIRGMDVTITTS-----------------------AQSDEEGRALLKAFGFPFMSRVA-K--APVTLPNGVSVT-L--- -N-D--R-QVEVKGKNGNMSLRL--HE-L--VELKQED-DA--IIF----S-P-TVDSKEAM-MHTGTMRSLLNNLVIGV NEGFEKRLQLIGVGY--RAQAAG-NK--VTLN--VGYSHPVEYTL-P-E-GVSAETP--T-QTEIVLKS-NDKQQLGQAA ADIRGFR------PPEPY---KGKGIRYSDEHVIRKEAK----------MIQVESMLEVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIKVTVKEAIPR-G-------RVKKGDVMNAVVVRTKKGVRRPDGSVLRFDDNAAVLLN-QNKA-PIATRIF GPVTRELR-GDQFMKIVSLAPEVLLR-L--NELSPGVGA-KKTAQRRG-RGIGSGL-GKTGGRGVKGQKSRSGSS-I--- -RSGF-E-GGQMPLYRRLPK-FG--FTSVRLSELVSIETLKAA-NLIRAR---------VML--SGE-V-T-K-A-YTF- KGIKVTKGAKQAIEAAGGSI-K---MHK--GRN---TGLA-HRGSTVAFG----------QIGLKSL--TRGRMTARQIE AARRTITRKI------KRGGKIWIRVFPDKPITNKPLEVRMGKGK---------GPVEYWVCEIKP-GKILYEL--EG-- ISEELAREALTLAAAKLPFKTTI-VKKAARLRRAKKTRAHI----RFLGVHRLTVNRTPRHIYAQIISP---N--GGEVI AQASTL-DSSL-RS------GAT-GNADAATSVGQMIAER--AKAAG-ITKVAFDRSGFKYH--GRVKALAEAARENGLE F--------------------------------------------------------------ME-VTAKLRGAAISAQK VRLVADEVRGKSIERALDILTYS---------------------------------NKKGAVFVKKCLNSAIAN----A- ENNN-GLDIDTLKVSTIYVDEGITLKRILPRAKGRADRISKRTCHITIKVGEMSKLRKGDTVIVIAGK------DK-GKQ GTVQAVKNDRI--K----VEGINIVTKHQK----PN-QAT-GVE-GGILKQEAFLHISNVA-ILNAQT-------QK--A --DRITYQF---GE--------DGKQR---LYRSNG---EVV--MGQKVHPIGIRLG--VV-KKHNANWYA------SPK Q--YSEYLINDIQVREYL--RKKLD-----SAMISKIMIERPT-G-AAKITIATARPGIVIGKKGEDIERLQKELTKIAQ VNIEEITS---PDLDAHLVAEGIASQLERRVMFRRAMKRAVQNSMRS-GAKGIKVELSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYSSVRAETTYGTIGVKVWIFMSMQDTVGDMLTRIRNAQMANKVSVAM-PNSKLRKSIADLLVNEGYVASAV VTE----E---N---NNKATLTIVLKYF----EG-------K---AVIETIQRFSRPGLRQHRGKDAIPTVKQGMGVAIV STSQGIMTDRAARAAGIGGEVVAFVAMANQRIRIRLKSFDHRLIDQSAQEIVDTAKRTGAQVCGPVPLPTRIERFNVLTS PHVNKDAR-DQYEIRTHKRMVDIVQPTDKTVDALMKLDLAAGVDVQIALASVLTGRVVSDKMDKSITVLIERLVRHPLYG KQLRRSTKIKAHDEN--NVCQQGDLVRIKETRPISKTKSWTLVDVVEKV------------------------------- -MPRSL-KKGPFIDA-HLFAKVETALE---TNSRK----PIKTWSRRSMILPQMVGLTLSVHNGRTHVPVIVSE-QMVGH KLGEFAPTRTYRGHG------I---DK----KAK------R- >GAMMA_Psychrobacter_sp_PRwf-1 Concatenation of 2 sequences MPIVKAKPTSPGRRFVEKVVHPH-LYKG------------RP-HAPLVEAQGRSGGRNNNGRITSRH-IGGGHKQH---- YRIIDFK-R--TK-DNIPATVERIEYDPNRTAHIALLKYA-DGERRYIIAPKKLKVGDTVLSGE-A-SP-IRPGNCLPLK NIPVGTTISNIELKIGKGAQMARSAGASVQLLGK--EGIYAILRLRSGETRRVHVNCRAVIGEVSNTENNLKSLGKAGAS -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRT----MGKH-PTTP---WGQKTKGLKTR-SNKRTDS---MIIRRR --------------------------------MAI---G-LVGKKCGMTRVFT-ETGA---------SIPVTVVEVDANR ITQIK----TND----T--DGY--QAIQITT-------GE--RVTA----------AQKGHFK----------------- ---AG-VKAGRGVWEFRV------TEEELEGR-----EA---GS-EIAA--D-L-FEAGQLVDVTGQSKGKGFQGGVKRH NFSM-QDATHGNSVSHRV-LGSTGQN-QSPG-KVFKGKKMPGQMGNKRVTVQGLEVVSVDAEKG---------------- ----------LLVIKGA-IPGANGGDVIVR-MNLKTVTG--------AAVELSDTAF----GR-EF-NEALVHQVVTAYL AGARQGTRAQKTRAE--------VS-GGGKKPW---------RQKGTGRAR--------AGS---TR-SP----IW---- VGGGRAFAAK-P-QDWSQKVNRKMYRGAMQCILAELVRQD----------------R-LILVDSI----TVS-A------ --PKTKLIV--TNEVD--E---NLYLAARNIPHVN-V---------------LGTNEVDPVSLIAFDK----VIMSVDAA KQFEARLKSLYNDQY----KQQIKDELGLENVMQVPKITKITLNMGVG-GASQDKKLLEGAVADMTAIAGQKPVITKARK SVAGFKIREEWPIGCKVTLRGEQMYEFLDRLIAIAIPRIRDFRGFSP-KAFDGRGNYSLGIKEQIVFPEVD-----YDKI DRLRGLDITITTS-----------------------AQDDEQGRALLKAFGFPFMSRVA-K--APVALPNGVSVT-L--- -N-G--Q-QVEVKGSKGTMSLHL--HD-L--VELKQED-SQ--LIL----S-P-VSDSKEAW-MHTGTMRSTLNNFVIGV SEGFERKLQLIGVGY--RAQVAG-NK--ITLN--VGYSHPVEYIL-P-E-GVTAETP--S-QTEIILKS-NDKQALGQAA AKIRGYR------PPEPY---KGKGIRYSDEHVVRKEAK----------MIQTETILEVADNSGARRVQCIKVLG-SHRR Y--ASVGDIIKVSVKEAIPR-G-------RVKKGDVMNAVVVRTKKGVRRPDGSVLRFDDNAAVLLN-QNKA-PIATRIF GPVTRELR-GDQFMKIVSLAPEVLLK-L--NELSPGVGA-KKTAHRKG-RGIGSGL-GKTGGRGVKGQKSRSGSG-V--- -RRGF-E-GGQMPLFRRVPK-FG--FTSVRLSELVSVETLKAA-NIIRAR---------IIL--SGE-I-T-K-A-YTF- KGVKVTKGAKAAIEAAGGTV-K---MHK--GRN---TGLA-HRGSTVAFG----------QFGLKSV--GRGRMTARQIE AARRTITRKV------KRGGKIWIRVFPDKPITNKPLEVRMGKGK---------GPVEYWVCEIKP-GKMLYEI--EG-- VSEELAREAFTLAAAKLPFKTTI-VKKAARLRRAKKTRAHI----RHLGVHRLVVNRTPRHIYAQIISP---T--GGEVL AQASTL-DASL-RS------GAT-GNVDAAAAVGKLIAER--GTSAG-ITKVAFDRSGFKYH--GRVKALADAARENGLE F--------------------------------------------------------------ME-VTAKLRGAAISAQK VRLVADEVRGKSIERALDILAFS---------------------------------NKKGAVFVKKCLESAIAN----A- EHNH-GLDIDTLKVSTIYVDEGITLKRILPRAKGRADRISKRTCHITVKVGEMAKLRKGDNVIVIAGK------DK-GKQ GTVLAVKNDRI--K----VEGINIVTKHQK----PN--AATGAE-GGIVKQEAFLHISNVA-IFNAQT-------QK--A --DRITYQF---DD--------EGKKR---VYRSNG---EVV--MGQKVHPIGIRLG--VV-KKHNANWYA------DPK Q--YSEYLLNDLQVRDYL--RKKLD-----NAMISHIMIERPT-G-AAKITISTARPGIVIGKKGEDIEKLQKELTKMAQ VNIEEITS---PDLDARLVAEGIASQLERRVMFRRAMKRAVQNSMRS-GAQGIKVELSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYASVRAETTYGTIGVKVWVFMSMQDTVADMLTRIRNAQMARKVSVAM-PSSKLRKSIADLLVQEGYIASAE VTD----E-GNG-----KATLSIELKYF----EG-------K---PVIEVIKRYSRPGLRQYRGKDAIPSVQQGLGVAIV STSKGIMSDRAARAAGIGGEIIAFVAMANQRIRIRLKSFDHRLIDQSAQEIVDTAKRTGAQVCGPVPLPTRIERFNVLTS PHVNKDAR-DQYEIRTHKRMLDIVQPTDKTVDALMKLDLAAGVDVQIALVGIVTGKVVSNKMDKSITVLIERKVRHPLYG KQIRRSTKIKAHDEN--NVCKEGDVVRIIETRPISKTKSWKLVDVVETA------------------------------- -MPRSL-KKGPFIDA-HLFAKVEKAVE---SNSRK----PIKTWSRRSMILPQMVGLTISVHNGRTHVPVIISE-QMVGH KLGEFAPTRTYRGHG------F---DK----KAK------K- >GAMMA_Psychromonas_ingrahamii_37 Concatenation of 2 sequences MAIVKCKPTSPGRRHLVKVVNND-LHKG------------KP-FAALLESKSKSGGRNNGGRITVRH-IGGGHKQH---- YRIVDFK-R--NK-DGIPAKVERLEYDPNRSANIALVLYS-DGERRYILAPKGLVAGDQIISGE-D-AS-IKVGNCLPMR NIPVGTTVHAVEMKPAKGAQIARSAGAYSQIVAR--DGAYVTLRLRSGEMRKIPTECRATIGEVGNAEHMLRQLGKAGAT -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGKS----SGGRHPVSP---WGMPTKGYKTR-KNKGTDQ---YIVRRR --------------------------------MTI---G-LIGRKVGMTRVFT-EDGV---------SIPVTVLECSPNR VTQVK----TLD----T--DGY--QALQVTA-------GS--KVNK----------PEAGHFK----------------- ---AG-VEAGRGLWEFTL------ADNEGADI-----KV---GA-ELSV--E-L-FNEINKVDVTGQSKGKGFQGAIKRW NFSM-QDATHGNSVSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEVVRVDIERN---------------- ----------LLLVKGA-VAGAKNGDVIIK--MELVLKD-AQ-----SALEVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSD--------VS-GGGKKPW---------RQKGTGRAR--------SGT---IR-SP----IW---- VGGGVTFAAR-P-QDHSQKVNKKMYRGAVKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTQLII--TEELD--E---NLFLAARNLYKVD-V---------------RDVQGIDPVSLIAFDK----VLVTAAAV KKIEAKLHDFYKDNV----VSDLQTQFGYTSVMQVPRIEKITLNMGVG-EALADKKVLENAASDMAAISGQKPLITKARR SVAGFKIREGYPIGCKVTLRGSRMWEFFERLVTIAIPRVRDFRGLNA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DKVRGLDITITTS-----------------------AKTDEEGRALLSAFNFPFMSRIA-K--APITVPSGVEVV-V--- -N-G--Q-NVAVKGNKGELVCLL--ND-A--VVIKLEE-GV--IRF----A-P--AEGKDGW-AQAGTARANVNNMVLGV TEGFKKTLLLQGVGY--RAQVAG-TI--VNLT--LGFSHPVAYQL-P-E-GITAVAK--S-QTEIILEG-ADKQVVGQAA AKIRAFR------PPEPY---KGKGVRYANEIVRRKEAK----------MIQMQSVLDVADNSGARRVMCIKVLG-SHRR Y--AAIGDIIKVTVKEAIPR-G-------KVKKGDVHSAVVVRTRKGVRRPDGAVIRFDRNAAVMLN-ANNQ-PIGTRIF GPVTRELR-NEKFMKIVSLAPEVLMK-L--NTLSPAAGA-KHAAKRVG-RGIGSGL-GKTAGRGHKGQKSRSGGS-I--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLNEIVTIETLKQA-GLLVAK---------VVL--SGE-I-S-R-S-VTV- QGLRVTKGARAAIEAAGGKI-K---MFK--GRN---RGLS--KGTEVSFG----------EFGLKAV--GRGRITARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITGKPLEVRQGKGK---------GNVEYYVAQTQP-GKVLYEM--EG-- VPEKLAREAFALAAAKLPLATTF-VKKASRLRRATRTRKKL----QELGATRLVINRTPRHTYAQVITA---D---AQVV ASASTL-EKEV-RAQI----SNG-GNKEAAQLIGKLVAER--AVEKG-ISKISFDRSGFQYH--GRVAALAEAAREAGLQ F--------------------------------------------------------------ME-ALAKHLYARSSAQK ARLVADQVRGLPVEKALELLSYS---------------------------------PKKAAVLIKKVVDSAIAN----A- EHNE-GADIDELVITKICVDEGPTMKRIMPRAKGRADRIMKRSCHITVVVSDAVKIKRDDQVIVITGK------DK-GKT GTIKTVLSN-G--KII--IEGVNTVKKHQK----PN-PQA-DVA-GGIIEQSAPMQISNVA-ILNSAT-------GK--A --DRVGFRL----E--------DGKVR---FFKSNN---ELV--MGQKVHPNGIRLG--IT-KAFSSTWYA------GKK D--FAANLFSDFEIRKFL--TEKLK-----NASLSKITIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRTAIAKMAQ INISEVRK---PELDAKLVADSISSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSEAHTVYGIIGVKVWIFMSMQDPISDMLTRIRNGQAASKVSVKM-PSSKQKVAIAAVLKAEGYVTEFV VAG----D--------TKPELEVTLKYF----EG-------K---KVIDTIKRVSRPGLRIYKGANDLPKVMAGLGIAII STSHGVMTDRAARKASIGGEIICYVSMQNQRIRIRLKAFDHKLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILVS PHVNKDAR-DQYEIRTHKRLIDIVEPTEKTVDALMKLDLAAGVDVQISLTRTLQGKVISAKMDKSIVVAIERKVKHPLYG KFMRRTTKLHVHDET--NQCSEGDTVLISECRPLSKTKSWTLVEIVNKV------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---SGEKK----PIKTWSRRSMIIPDMIGLTIAVHNGRQHVPVFVTD-EMVGQ KLGEFAPTRTYRGHT------S---DK----KTK------KK >GAMMA_Saccharophagus_degradans_2-40 Concatenation of 2 sequences MPIVKRKPTSAGRRFVVNVVNAD-LHKG------------AP-HAPLLEKKSKSGGRNNNGRITTRH-IGGGHKQH---- YRVIDFR-R--NK-DGIPAKVERLEYDPNRTAYIALVCYA-DGERRYIIAPKGVKAGDVIQSGD-A-AP-IKPGNALPLR NIPVGSVVHCIEMKPGKGAQIARSAGTSVQLVAR--EGQYCTLRLRSGEMRKILSECRATLGEVSNSEHNLRSLGKAGAS -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGTPTKGYKTR-SNKR-TD-K-MIVRRR --------------------------------MTI---G-IVGRKSGMTRIFT-DDGL---------SVPVTVVEVDPNR ITQVK----SVE----T--DGY--AAVQVTV-------GS--RVSK----------PEAGHFK----------------- ---AE-VEAGRTVLELRN--------ESGEQF-----EV---GG-LLTV--E-A-FEAGQKVDVTGASKGKGFAGVIKRY NFRM-QDATHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAARVTTQNLEVVRVDVERN---------------- ----------LLLIKGA-VPGAPGGDVIIR--MELSIAT-PQGAK--GTVSVSEAAF----GR-EF-NQDLVHQAVVAFM AGARQGTKAQKNRAA--------VS-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----LW---- RSGGVTFAAE-P-RDHSQKLNKKMYRAAIRCILSELARQE----------------R-LVVVEEF----DLD-A------ --PKTKLII---GEDS--E---NLYLAARNLHKVD-V---------------RDVNGLDPVSLIRFDK----VVVTVAAL KKLE----------------------------MEIPRITKITLNMGVG-EALADKKVLENAVSDLEKIAGQKAVVTRARK SIAGFKVREGWPIGCKVTLRSDRMYEFLDRLISISIPRIRDFRGISP-KQFDGRGNFSMGVSEQIIFPEID-----YDKI DKLRGLDICISTT-----------------------ARNNDEGRALLKAFNFPFMSRVA-N--NPVQLPSGVQVD-L--- -K-G--S-DLSVKGSKGAMSLSV--HS-S--VAVVQED-NV--LTF----A-A--KDGKSSK-AMAGTVRSLVNNMVTGV SVGFEKKLQLVGVGY--RTKVTG-NV--LNLT--LGFSHPVDYVL-P-E-GVTAETP--T-QTEIVLKC-SDKQLLGQVA AEIRAFR------PPEPY---KGKGVRYADENVRRKEAK----------MIQTQSYLDVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKVTVKEAIPR-G-------KVKKGQVMNAVVVRTKKGVRRADGSLIRFDDNAAVILN-AQNA-PVGTRIF GPVTRELR-GEKFMKIISLAPEVLMR-L--NTLSPAPGR-VSAKKRVG-RGIGSGL-GKTAGRGHKGLKSRSGGS-V--- -KPGF-E-GGQMPLQKRLPK-FG--FTSVRLAELIDIEALRAA-DLIDAK---------VFL--SGE-L-T-K-A-VTI- KGLMVTKGAKAAIEAAGGKI-K---QQK--GRN---RGLA-HRGSKVSFG----------EFALKAT--GRGRITARQIE AARRAMTRHV------KRGGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVCQIQP-GKVLYEM--EG-- VSEELAREAFTLAAAKLPVTTTF-VKKQSRIRRARRARAKM----KELGVSRLCVNRTPRHIYAQVISA---E--GDRVV ASASTL-DKDL-RS------GST-GNRDAASAVGKLIAER--AKAAG-VSTVAFDRSGFKYH--GRVKALADAAREGGLE F--------------------------------------------------------------ME-VAAKLRGAGMSAQK ARLVADQIRGKSVEEALDLLTFS---------------------------------TKKGAALIKKVLESAVAN----A- EHNE-GADVDELKVSTIFVDEGLTMKRIRPRAKGRADRILKRTCHITVKVADMRKIKRNDEVIVITGK------DK-GKR GKVNRVLSD-D--RLI--VSGVQIIKKHQK----PN--PQMGIA-GGIIEKEAPIQASNVA-IFNPAT-------NK--A --DRVGFKL---QE--------DGKIR---VFKSNG---EAI--MGQKVHPTGIRLG--IV-KKHTSTWYA------G-K A-EYADKLNQDLQVRKYI--QNALA-----HASVSRIDIERPA-N-TARVTIHTARPGIVIGKKGEDVEKLRTELTKQVH INIEEIRK---PDLDAALAAQSVAQQLERRVMFRRAMKRTVQNAMRQ-GAEGVKVQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATAEASTTYGIIGVKVWIFMSMQDPIADMLTRIRNAQQVGKTSVTM-PSSKLKKSIAGVLKEEGYVGEFS VND----A--------AKAELTVELKYF----EG-------K---PVIAELDRVSRPGLRSYVGKDELPSVRGGLGIAIV STSKGVMTDRAARAAGVGGEILCTVFMQNQRIRIRLKAFDHKLIDASTQEIVETAKRTGAQVRGPIPLPTRKERYTVLVS PHVNKDAR-DQYEIRTYKRLLDIVEPTEKTVDALMKLDLAAGVEVQISLVRTLTGKVVSDKMEKSIVVLIERRVKHPVYG KYVSKSTKMKAHDEA--NDCKIGDTVTIAESRPLSKTKSWTLVKIEERA------------------------------- -MPRSL-KKGPFIDH-HLLSKVEAAAE---KNDRR----PIKTWSRRSMILPNMVGLTLAVHNGRQHVPVLVNE-EMVGH KLGEFAVTRLYRGHV------A---DK----KAK------R- >GAMMA_Salmonella_enterica_enterica_sv_Choleraesuis_SC-B67 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLVEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEY-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGG-VPGATGCDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VNKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--AGADVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------AAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKMHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Salmonella_enterica_enterica_sv_Typhi_Ty2 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLVEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEY-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGG-VPGATGCDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VNKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--AGADVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNTAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKMHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Salmonella_typhimurium_LT2 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLVEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEY-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGG-VPGATGCDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VNKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NA--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--AGADVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKMHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Serratia_proteamaculans_568 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-HAPLLEKLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-DGVAAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKVGNALPMR NIPVGSTVHNVEMKPGKGGQIARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVPVDCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGKN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKLGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----DLA----N--DGY--RAVQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRT--------AEGEEF-----TA---GQ-NISV--E-I-FAEVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGHLGDERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIIVEKF----SVE-A------ --PKTKLIV--TGELD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKQLMSQFDYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFNFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTV--HN-A--VEVKQEA-NA--LTF----A-P--REGANAW-AQAGTTRALLNAMVVGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHQL-P-A-GITAECP--S-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLTVADNSGARRVMCIKVLG-SHRR Y--AGIGDVIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTAGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSELIDLNTLKAA-NVVGAK---------VML--SGE-I-A-R-P-VTL- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEEVAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKI----KELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTL-EKAV-TEQL----KYS-GNKDAAAAVGKALAER--ALEKG-ISKVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLAYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEIIVLTGK------DK-GKR GKVKNVLSA-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNIA-LFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWYA------NTK E--FADNLDSDFKVRQFL--IKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVANIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANLLKEEGFIEDFK IEG----D--------TKPVLELVLKYF----QG-------K---AVVESIQRISRPGLRIYKKKDALPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLNRTLQGRVISDKMEKSMVVAIERTVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -----------------------------------------------------MIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_amazonensis_SB2B Concatenation of 2 sequences MAIVKCKPTSPGRRGVVKIVNSD-LHKG------------KP-FAGLLAKKSKTGGRNNTGRITTRH-VGGGHKQH---- YRLIDFK-R--NK-DGIPGKIERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDKVVSGI-D-AD-IKVGNALPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGEYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----TLE----N--DGY--RALQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEMRL------GEGEGEGI-----EV---GA-ELNV--E-I-FADVQKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRA-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDVERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AS-----RALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------IT-GTGKKPW---------RQKGTGRAR--------AGG---IK-GP----LW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALMSILSELVRQE----------------R-LVVVEQF----AVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNK----VLVTADAV KQIEAKLHDKYKETV----IAELSKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKIMENAVRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFFERLLDIAIPRIRDFRGLSA-KSFDGRGNYAMGVREQIIFPEID-----YDKI DRVRGMDIVITTT-----------------------AKNDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-G--Q-EITVKGGKGTLTRVI--NS-A--VAVTVED-GA--IKF----A-P--VEGVNAW-AQAGTARALINNMVVGV SQGFEKKLQLVGVGY--RAKVAG-SD--VDLS--LGFSHPLVHKL-P-A-GVTAECP--S-QTEIVLRS-IDKELVGQVA AEIRGYR------PPEPY---KGKGVRYANEEVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMR-L--NTLSPAVGA-KSAPKRVG-RGIGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRLGELIDLNALKDA-NVVTAK---------VVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--AGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHV------KRQGKIWIRVFPDKPITAKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--DG-- VSEELAREAFGLAAAKLPIKTTF-VKKSSRLRRATRARKKI----QELGVHRLVVHRTPRHIYAQVINP---E---AQVV AAASTV-EKSI-KEAL----KST-GNVDAAKAVGKAIAER--AVEKG-VTVVAFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-VLAKHRFARTSPQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVVDSAIAN----A- EHNE-GADIDDLKIAKVFVDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRREDEVIVLTGK------DK-GKR GKVTRVLVT-G--KVV--VEGINLVKKHTK----PN--PQLGIT-GGIVEKEAAIQVSNVA-IFNPAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNG---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLHSDWEVRKFL--EKKLE-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAEVAKIAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSESHTTYGVIGIKVWVFMSMQDPIADMLTRIRNGQAANKVSVKM-PSAKLKVAIAKLLKDEGYITDYA VAS----E---G----NKAELEVTLKYF----QG-------R---PVVETIQRVSRPGLRIYKGKDELPKVMGGLGIAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKSITVAVERLVKHPIYG KFIKRTTKIHAHDEL--NQCNEGDIVTIRECRPLSKTKSWTLVDVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---AGDKK----PIKTWSRRSMIIPQMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_baltica_OS155 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNTD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--DK-DGIPAKIERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDKIQSGV-A-AE-IKTGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---SG-VEAGRGLWEMRL------VDGEGEGI-----EV---GA-ELNV--D-I-FADVAKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLVVVRVDVERN---------------- ----------LLLVRGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQE----------------R-LVVVESF----GVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELAKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKIMDHAVRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTT-----------------------AKNDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-E--Q-TLTVKGGKGSLTRVI--NN-A--VNVVIEA-GV--VKF----L-P--VEGSNAW-AQAGTTRALVNNMVVGV SQGFERKLKLVGVGY--RAKLVG-SD--IDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTDIVLRG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEVVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-NEQFMKIVSLAPEVLMR-L--NTLSPAAGS-KHAPKRVG-RGMGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRVLELIDLNALKDA-NVITAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEVIAREAFALAAAKLPIKTTF-VKKTSRLRRATRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVL AAASTV-EKAV-KELL----KST-GNVDAAKAVGKFVAER--AIEKG-VTSVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDAAKIRREDEVIVLAGK------DK-GKR AKVSQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEKEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YASNLNSDWEVRKFL--VEKLQ-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAAVSKLAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVQVSGRLGGAEIARDEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANHVSVKM-PSAKLKVAIAKLLKDEGYIADYA VAD----E--------AKPELEVTLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKSITVAIERQVKHPIYG KYIKRTTKIHAHDET--NQCNEGDLVAIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_baltica_OS195 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNTD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--DK-DGIPAKIERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDKIQSGV-A-AE-IKTGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---SG-VEAGRGLWEMRL------VDGEGEGI-----EV---GA-ELNV--D-I-FADVAKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLVVVRVDVERN---------------- ----------LLLVRGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQE----------------R-LVVVESF----GVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELAKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKIMDHAVRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTT-----------------------AKNDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-E--Q-TLTVKGGKGSLTRVI--NN-A--VNVVIEA-GV--VKF----L-P--VEGSNAW-AQAGTTRALVNNMVVGV SQGFERKLKLVGVGY--RAKLVG-SD--IDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTDIVLRG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEVVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-NEQFMKIVSLAPEVLMR-L--NTLSPAAGS-KHAPKRVG-RGMGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRVLELIDLNALKDA-NVITAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEVIAREAFALAAAKLPIKTTF-VKKTSRLRRATRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVL AAASTV-EKAV-KELL----KST-GNVDAAKAVGKFVAER--AIEKG-VTSVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDAAKIRREDEVIVLAGK------DK-GKR AKVSQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEKEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YASNLNSDWEVRKFL--VEKLQ-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAAVSKLAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVQVSGRLGGAEIARDEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANHVSVKM-PSAKLKVAIAKLLKDEGYIADYA VAD----E--------AKPELEVTLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKSITVAIERQVKHPIYG KYIKRTTKIHAHDET--NQCNEGDLVAIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_denitrificans_OS217 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNTD-LHKG------------KP-FAALLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--NK-DGIPAKVERIEYDPNRTAHIALVLYA-DGERRYILAAKGMKSGDPIQSGV-G-SE-IKTGNSMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVIAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------AEAGHFK----------------- ---GG-VEAGRGLWEMRL------ADGEGEGI-----EV---GA-ELNV--D-I-FAETVKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLAHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAEQVTTQNLHVVRVDSERN---------------- ----------LILVRGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQE----------------R-LVVVESF----GVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELAKKFGYSSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPIVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTS-----------------------AKTDEEGHALLTAFNFPFMSRVA-K--APVTIPAGVEVT-L--- -N-E--Q-TLTVKGSKGSLTRVI--NS-A--VNVVIED-AQ--VKF----L-P--VEGDGAW-AQAGTARALVNNMVVGV SQGFVKKLKLVGVGY--RAKIAG-SD--LDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTEIVLSG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEVVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANLA-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMR-L--NTLSPAAGS-KSAPKRVG-RGIGSGL-GKTAGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSVRLLELIDLNTLKDA-NVLTAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHV------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--DG-- VPESLAREAFALASAKLPIKTTF-VKKTSRLRRALRARKKI----QELGVNRLVVHRTPRHIYAQVISP---E---AQVL AAASTV-EKTV-KELL----KST-GNVDAAKAVGKIVAER--AIEKG-VAIVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVSKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELRVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVADAAKIRREDEIIVLAGK------DK-GKR AKVSQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVT-GGVIEKEAPIQTSNVA-IFNQAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELI--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLNSDWEVRQYL--TEKLK-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAQVAKIAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANHVSVKM-PSAKLKVAIAKLLQDEGFITGYA VAD----E--------AKPELEITLKYF----QG-------K---PVVETIQRVSRPGLRIYKGKDELPKVMGGLGIAIV STSQGLMTDRAARQNGTGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKSITVAIERQVKHPLYG KYIKRTTKIHAHDET--NQCNEGDVVTISQCRPLSKTKSWALVEVVTKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_frigidimarina_NCIMB_400 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNTD-LHKG------------KP-FAGLLAKKTKSGGRNNTGRITVRH-VGGGHKQH---- YRIVDFK-R--NK-DGIPAKVERLEYDPNRTAHIALVLYA-DGERRYILAAKGMKAGDPIQSGL-D-AE-IKTGNARPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGT---------SIPVTVIEIAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------AEAGHFK----------------- ---GG-VEAGRGLWEMRL------ADGEGEGI-----EV---GA-EINV--D-I-FADTVKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLAHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAEQVTTQNLHVVRVDAERN---------------- ----------LLLVRGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSIFSELVRQE----------------R-LVVVESF----GVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELAKKFGYSSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPIVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTT-----------------------AKNDEEGRALLDAFNFPFMSRVA-K--APVTVPAGVEVT-L--- -N-E--Q-TLTVKGSKGSLTRVI--NN-A--VNVVIED-AQ--VKF----L-P--VDGSNAW-AQAGTARALVNNMVVGV SQGFVKKLKLVGVGY--RAKIAG-SD--LDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTEIVLSG-VDKQVVGQVA AEIRGYR------PPEPY---KGKGVRYDDEIVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANLA-PIGTRIF GPVTRELR-NDKFMKIVSLAPEVLMR-L--NTLSPAAGS-KSAPKRVG-RGIGSGL-GKTAGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSVRLLELVDLNALKDA-NVITAK---------IVL--SGT-I-D-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHV------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--DG-- VPESLAREAFALASAKLPLKTTF-VKKTSRLRRALRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVL AVASTV-EKAV-KELL----KST-GNVDAAKAVGKIVAER--AIEKG-VATVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVSKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVADAAKIRREDEVIILAGK------DK-GSR GKVSQVLPT-G--KLI--VEGFNLVKKHQK----PN--PQLGVA-GGVIEKEAPMQASNVA-IFNQAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------D-K S-DYANNLNSDWEVRQYL--TEKLK-----AASVSKIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEVLRAYVSKIAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVQVSGRLGGAEIARAEWYREGRVPL- -HTLRADIDYSTAESHTQYGVIGIKVWIFMSMQDPIADMLTRIRNGQAANHVSVKM-PSAKLKVAIAKLLKDEGFITEYA VAD----E--------AKPELEITLKYF----QG-------K---PVVETIQRVSRPGLRIYKGKDELPKVMGGLGIAIV STSQGLMTDRAARQNGTGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLARTLQGKVISNKMDKSITVAIERQVKHPIYG KYIKRTTKIHAHDET--NQCNEGDFVAISQCRPLSKTKSWTLAEVVTKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_halifaxensis_HAW-EB4 Concatenation of 2 sequences MAVIKCKPTSPGRRHLVKVVNSD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-IGGGHKQH---- YRLIDFK-R--NK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDKIQSGI-D-AE-IKSGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVIAR--DGAYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGQPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFN-EDGA---------SVPVTVIEIAANR VTQVR----TLD----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---AG-VEAGRGLWEMRL------ADGEGEGI-----EV---GA-ELNV--D-I-FADIAKVDVTGQSKGKGFQGGIKRW NFAM-QDATHGNSLAHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLEVIRVDAERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSEATF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGT---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSIFSELVRQD----------------R-LIVVESF----GVD-A------ --PKTKLIV--TPEVD--E---NLFLAARNLYKVD-V---------------RDVAGVDPVSLIAFDK----VLVTAEAI KQIEAKLHDKYKETV----SPELVKKFGFTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSV-KSFDGRGNYAMGVREQIIFPEIQ-----YDKI DKIRGMDIVITTS-----------------------AKNDEEGRALLEGFNFPFMSRVA-K--APVAIPAGVEVT-L--- -N-E--Q-TITVKGTKGSLTRVI--NS-D--VSVVVED-NE--IKC----S-P--VESAKTA-AQAGTARALINNMVVGV TEGFVKKLTLVGVGY--RAKLAG-KD--IDLT--LGFSHPLVHKL-P-D-GVTAECP--S-QTEIVLSG-TDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQMQSTLEVACNSGARRVQCIKVLG-SHRR Y--AGIGDVIKVSVKEAIPR-G-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANLA-PIGTRIF GPVTRELR-TERFMKIVSLAPEVLMR-L--NTLSPAAGA-KSAAKRVG-RGIGSGT-GKTCGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSIRISELIDLNALKDA-NLVTAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTQGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEELAREAFTLAAAKLPLKTTF-VKKTSRLRRALRARKKI----QELGVNRLVVHRTPRHTYAQVISP---E---NVVL AAASTA-EKAV-TEQL----KYT-GNVDAAKVVGKTVAER--AIEKG-VAVVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSPQK CRLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRRQDEVIVLAGK------DQ-GKR GKVSQVLPT-G--KLI--VEGLNLVKKHQK----PN--PQLGVA-GGIVEQEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLSSDWEVRKFL--EKKLK-----QASVSKIVIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRNAVAKLAQ INIAEIRK---PELDAKLVADGIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWVFMSMQDPIADMLTRIRNGQAAKHVSVKM-PSAKLKIAIAQMLKEEGYITDYA VAD----E--------AKPELEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRTARQNGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILTS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVLSDKMDKSITVAIERKVKHPLYG KFIKRTTKIHAHDEQ--NQCNAGDLVTIRECRPLSKTKSWTLVEVISKA------------------------------- -----------------MLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGMTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_loihica_PV-4 Concatenation of 2 sequences MAVIKCKPTSAGRRHVVKVVNSD-LHKG------------KP-FAGLLAKKAKSGGRNNTGRITVRH-VGGGHKQH---- YRIVDFK-R--NK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDQIQSGI-D-AE-IKAGNALPLR NIPVGSVVHAVEMKPGKGAQIARSAGTYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGA---------SIPVTVIEIAANR VAQVK----TLE----T--DGY--RALQITT-------GT--KITK----------PEAGHFK----------------- ---AG-VEAGRGLWEMRL------ADGEGEGI-----EV---GA-ELNV--D-I-FADVAKVDVTGQSKGKGFQGGIKRW NFRT-QDATHGNSLAHRA-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDAERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGT---VK-GP----IW---- RGGGVSFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LVVVESF----GVE-A------ --PKTKLIV--TPEID--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFEK----VLVTADAV KQIEAKLHDKYKETV----IAELSKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIRDGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KSFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTT-----------------------AKNDEEGRALLDAFNFPFMSRVA-K--APVAIPAGVEVT-L--- -N-E--Q-TITVKGAKGSLTRVI--NA-D--VSVVVEN-NE--IKC----S-P--AEGVTSA-AQAGTARALINNMVVGV NEGFERKLTLVGVGY--RAKIAG-NG--IDLT--LGFSHPLVHQL-P-D-GVTAECP--S-QTEIVLKS-TDKQLVGQVA AEIRGYR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQMQSTLEVACNSGARRVQCIKVLG-SHRR Y--AGIGDVIKVSVKEAIPR-G-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANLA-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMK-L--NTLSPAAGA-KSAAKRVG-RGIGSGL-GKTAGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSIRVSELVDLNALKDA-NLVTAK---------VVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------EFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEELAREAFTLAAAKLPIKTTF-VKKTSRLRRATRARKKI----QELGVNRLVVHRTPRHTYAQVIDA---N---AQVV AAASTA-EKAV-SEQL----KYT-GNVEAAKAVGKTIAER--AIEKG-VTVVAFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-VLAKHRFARTSPQK CRLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGKVFVDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRREDEVIVLAGK------DK-GKR GKVSRVLPT-G--KLI--VEGINLIKKHQK----PN--PQMGVT-GGIVEKEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLSSDWEVRKFL--EKKLK-----QASVSKIVIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRNEVAKLAQ INIAEIRK---PELDAKLVAEGIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTAESHTQYGVIGVKVWVFMSMQDPIADMLTRIRNGQAANKVSVSM-PSAKLKVAIAQTLKEEGYITDYT VAG----E--------AKPVLEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNDLPKVMGGLGVAIV STSKGLMTDRAARQQGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVLSNKMDKSITVAIERKVKHPLYG KFIKRTTKIHAHDET--NQCNAGDIVTIRECRPLSKTKSWTLVEVVTKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGMTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_oneidensis_MR-1 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNSD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--DK-DGIPAKIERLEYDPNRTAHIALVLYA-DGERRYILAAKGMQAGDKIQSGV-E-AE-IKTGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---SG-VEAGRGLWELRL------ADGEGEGI-----EV---GA-ELNV--G-I-FADVAKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDVERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGG---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LVVVESF----SVE-A------ --PKTKLIV--TSEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELTQKFGYTSVMQVPRIEKITLNMGVG-EAVADKKVMEHAVRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTS-----------------------AKTDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-E--Q-TLTVKGAKGSLTRVI--NN-A--VNVVIEN-GV--IKF----L-P--VEGVGAW-AQAGTTRALVNNMVVGV SQGFERKLKLVGVGY--RAKLVG-AD--IDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTDIVLRG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEEVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-NEQFMKIVSLAPEVLMR-L--NTLSPAAGA-KHAPKRVG-RGMGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRVLELIDLNALKDA-NVITAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEVIAREAFALAAAKLPIKTTF-VKKTSRLRRAIRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVV AAASTV-EKAV-KEQL----KST-GNVDAAKAVGKFVAER--AIEKG-VTNVAFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDAAKIRRQDEVIVLAGK------DK-GKR AKVAQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEKEAPIQASNVA-IFNPVT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLNSDWEVRKYL--ADKLQ-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAAVSKLAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGIKVWIFMSMQDPIADMLTRIRNGQAANKVSVKM-PSAKLKVAIAKLLKEEGYIADYA VAD----E--------AKPELEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKTITVAIERQVKHPIYG KYIKRTTKIHAHDEA--NQCNEGDVVAIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_pealeana_ATCC_700345 Concatenation of 2 sequences MAVIKCKPTSPGRRHLVKVVNSD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-IGGGHKQH---- YRLIDFK-R--NK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAAKGMKAGDKIQSGI-D-AE-IKSGNALPLR NIPVGSVVHAVEMKPAKGAQIARSAGAYVQVIAR--DGAYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGQPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFN-EDGA---------SVPVTVIEIAANR VTQVR----TLD----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---AG-VEAGRGLWEMRL------ADGEGEGI-----EV---GA-ELNV--D-I-FADIAKVDVTGQSKGKGFQGGIKRW NFAT-QDATHGNSLAHRA-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLEVIRVDAERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSEATF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGT---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSIFSELVRQD----------------R-LIVVESF----GVE-A------ --PKTKLIV--TPEVD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFNK----VLVTAEAI KQIEAKLHDKYKETV----SPELVTKFGFTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSV-KSFDGRGNYAMGVREQIIFPEIQ-----YDKI DKIRGMDIVITTS-----------------------AKNDEEGRALLEGFNFPFMSRVA-K--APVAIPAGVEVT-L--- -N-E--Q-TITVKGTKGSLTRVI--NS-D--VSVVVED-NE--IKC----S-P--VESAKTA-AQAGTARALINNMVVGV TDGFVKKLQLVGVGY--RAKLAG-KD--IDLT--LGFSHPLVHKL-P-D-GVTAECP--S-QTEIVLSG-TDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQMQSTLEVACNSGARRVQCIKVLG-SHRR Y--AGIGDVIKVSVKEAIPR-G-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANLA-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMR-L--NTLSPAAGA-KSAAKRVG-RGIGSGT-GKTCGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSIRISELIDLNALKDA-NLVTAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTQGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEELAREAFTLAAAKLPLKTTF-VKKTSRLRRALRARKKI----QELGVNRLVVHRTPRHTYAQVISP---E---NVVL AAASTA-EKAV-TEQL----KYT-GNVDAAKVVGKTVAER--AIEKG-VAVVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSPQK CRLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRRQDEVIVLAGK------DQ-GKR GKVSQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEQEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLSSDWEVRKFL--EKKLK-----QASVSKIVIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRNAVAKLAQ INIAEIRK---PELDAKLVADGIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWVFMSMQDPIADMLTRIRNGQAAKHVSVKM-PSAKLKIAIAKMLKEEGYITDYA VAD----E--------AKPELEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSQGLMTDRTARQNGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILTS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVLSDKMDKSITVAIERKVKHPLYG KFIKRTTKIHAHDEQ--NQCNAGDIVTIRECRPLSKTKSWTLVEVVTKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGMTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_piezotolerans_WP3 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNSD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITSRH-IGGGHKQH---- YRLIDFK-R--NK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYIIAAKGMKAGDSIQSGI-D-AE-IKSGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVIAR--DGAYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGQPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFN-EDGA---------SVPVTVIEIAANR VTQVK----TLD----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---AG-VEAGRGLWELRL------ADGDGEGI-----EV---GA-ELNV--D-I-FADIAKVDVTGQSKGKGFQGGIKRW NFHA-QDMTHGNSLAHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDIVRVDAERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VV-GSGKKPW---------RQKGTGRAR--------AGT---VK-GP----IW---- RGGGVTFAAK-A-QDHSQKVNKKMYRGALKSIFSELVRQD----------------R-LVVVESF----GVE-A------ --PKTKLIV--TPEVD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFNK----VLVTAEAI KQIEAKLHDKYQETV----SPELVKKFGFTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGMSV-KSFDGRGNYAMGVREQIIFPEIE-----YDKI DKIRGMDIVITTS-----------------------AKNDEEGRALLEGFNFPFMSRVA-K--APVAIPAGVEVT-L--- -N-E--Q-TITVKGTKGSLTRVI--NA-D--VSVVVED-NE--IKC----S-S--VEGVKTA-AQAGTARALINNMVVGV TAGFEKKLQLIGVGY--RAKIAG-KG--VDLT--LGFSHPLVHEL-P-D-GVTAECP--S-QTEIVLKG-TDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQMQSTLEVACNSGARRVQCIKVLG-SHRR Y--AGIGDVIKVSVKEAIPR-G-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANLA-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMR-L--NTLSPAAGA-KSAAKRVG-RGIGSGL-GKTAGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSVRISELIDLNALKDA-NLVTAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------EFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEELAREAFALAAAKLPLKTTF-VKKTSRLRRATRARKKI----QELGVNRLVVHRTPRHTYAQVISP---A---NVVL AAASTA-EKAV-SEQL----KYT-GNVDAAKAVGKTVAER--AIEKG-VAVVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSPQK CRLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRRQDEVIVLAGK------DQ-GKR GKVSQVLTT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEQEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLSSDWEVRKFL--EKKLK-----QASVSKIVIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRNAVAKLAQ INIAEIRK---PELDAKLVADGIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWVFMSMQDPIADMLTRIRNGQAAKHVSVKM-PSAKLKIAIAKVLKEEGYITDYA VAD----E--------AKPELEVTLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRTARQNGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILTS PHVIKMRV-----ISTNFVLTNVLLTS----------------------IRTLQGRVLSNKMDKSITVAIERKVKHPLYG KFLKRTTKIHAHDEQ--NQCNAGDVVTIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_putrefaciens_CN-32 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNTD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--DK-DGIPAKIERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDKIQSGV-E-AE-IKTGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GIR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---SG-VEAGRGLWEVRL------EDGEGEGI-----EV---GA-ELNV--D-I-FADVAKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLVVVRVDVERN---------------- ----------LLLVRGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQE----------------R-LVVVESF----GVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELAKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTS-----------------------AKTDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-E--Q-TLTVKGAKGSLTRVI--NN-A--VNVVIED-GV--VKF----L-P--VEGVNAW-AQAGTTRALVNNMVVGV SQGFERKLKLVGVGY--RAKLVG-AD--IDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTDIVLRG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEEVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-NEQFMKIVSLAPEVLMR-L--NTLSPAAGS-KHAPKRVG-RGMGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRVLELIDLNALKDA-NVITAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEVIAREAFALAAAKLPIKTTF-VKKTSRLRRAIRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVV AAASTV-EKAV-KEQL----KST-GNVDAAKAVGKFVAER--AIEKG-VTSVAFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDAAKIRREDEVIVLAGK------DK-GKR AKVSQVLPT-G--KLI--LEGINLVKKHQK----PN--PQLGVA-GGIVEKEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLNSDWEVRKFL--VEKLQ-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAAVSKLAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVQVSGRLGGAEIARDEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVSVKM-PSAKLKVAIAKLLKEEGYIADYA VAD----E--------AKPELEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKSITVAIERQVKHPIYG KYIKRTTKIHAHDET--NQCNEGDLVAIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_sediminis_HAW-EB3 Concatenation of 2 sequences MAIIKCKPTSAGRRHVVKVVNTD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-IGGGHKQH---- YRIIDFK-R--IK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDPIQSGI-D-AE-IKVGNALPLR NIPIGSVVHAVEMKPGKGAQIARSAGTYVQVVAR--DGEYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---TGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFA-EDGV---------SIPVTVIEIASNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---AG-VEAGRGLWEVRL------ADGEGESI-----EV---GA-ELNV--D-I-FADVAKVDVTGQSKGKGFQGGIKRW NFHA-QDMTHGNSLAHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDAERN---------------- ----------LLLVKGA-VPGATNGNLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VI-GSGKKPW---------RQKGTGRAR--------AGT---VK-GP----IW---- RGGGVTFAAK-A-QDHSQKVNKKMYRGALKSIFSELVRQD----------------R-LIVVESF----SVE-A------ --PKTKLIV--TPEID--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFNK----VLVTADAV KQIEAKLHDKYQETV----SPELAKKFGFTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIRDGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGMSA-KSFDGRGNYAMGVREQIIFPEIE-----YDKI DKIRGMDIVITTS-----------------------AKNDEEGRALLEAFNFPFMSRVA-K--APVAIPAGVEVT-L--- -N-E--Q-TITVKGTKGSLTRVI--NA-D--VSVVVEN-NE--IKC----S-S--VEGVKTN-AQAGTARALINNMVVGV TAGFEKKLQLIGVGY--RAKIAG-KG--VDLT--LGFSHPLVHEL-P-D-GVTAVCP--S-QTEIVLSG-TDKQLVGQVA AEIRGYR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-G-------KAKKGDVYSAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANNA-PIGTRIF GPVTRELR-NEQFMKIVSLAPEVLMR-L--NTLSPAAGA-KSAAKRVG-RGIGSGT-GKTCGRGHKGQKSRSGGG-V--- -RVGF-E-GGQMPLKIRLPK-FG--FTSVRISELVDLNALKDA-NLVTAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------DFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--DG-- VTEELAREAFALAAAKLPLKTTF-VKKTSRLRRATRARKKI----QELGVNRLVVHRTPRHTYAQVISP---D---SQVL AAASTA-EKAV-TEQL----KYT-GNVDAAKAVGKTVAER--AIEKG-VTVVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSPQK CRLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRREDEVIVLAGK------DQ-GKR GKVSQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEQEAPIQASNVA-IFNSAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLTSDSEVRKFL--EKKLK-----QASVSKIVIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRNAVAKLAQ INIAEIRK---PELDAKLVADGIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTAESHTQYGVIGVKVWVFMSMQDPIADMLTRIRNGQAANKVSVSM-PSAKLKVAIAKTLKEEGYITDYA VAD----E--------TKPVLEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKSKDELPKVMGGLGVAIV STSKGLMTDRTARQNGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILTS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVLSNKMDKSITVAIERKVKHPLYG KYLKRTTKIHAHDEQ--NQCNAGDVVTIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_sp_ANA-3 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNSD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--DK-DGIPAKIERLEYDPNRTAHIALVLYA-DGERRYILAAKGMQAGDKIQSGV-E-AE-IKTGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---SG-VEAGRGLWELRL------ADGEGEGI-----EV---GA-ELNV--G-I-FADVAKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDVERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGG---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LVVVESF----SVE-A------ --PKTKLIV--TSEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELTKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKVMEHAVRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTS-----------------------ANSDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-E--Q-TLTVKGAKGSLTRVI--NN-A--VNVVIED-GV--IKF----L-P--VEGVGAW-AQAGTTRALVNNMVVGV SQGFERKLKLVGVGY--RAKLVG-SD--IDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTDIVLRG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEEVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-SEQFMKIVSLAPEVLMR-L--NTLSPAAGA-KHAPKRVG-RGMGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRVLELIDLNALKDA-NVITAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEVIAREAFALAAAKLPIKTTF-VKKTSRLRRAIRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVV AAASTV-EKAV-KEQL----KST-GNVDAAKAVGKFIAER--AIEKG-VTTVAFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDAAKIRRQDEVIVLAGK------DK-GKR AKVAQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEKEAPIQASNVA-IFNPVT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLNSDWEVRKYL--ADKLQ-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAAVSKLAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGIKVWIFMSMQDPIADMLTRIRNGQAANKVSVKM-PSAKLKVAIAKLLKEEGYIADYA VAD----E--------AKPELEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKTITVAIERQVKHPIYG KYIKRTTKIHAHDEA--NQCNEGDVVAIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_sp_MR-7 Concatenation of 2 sequences MAVIKCKPTSPGRRHVVKVVNSD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRLIDFK-R--DK-DGIPAKIERLEYDPNRTAHIALVLYA-DGERRYILAAKGMQAGDKIQSGV-E-AE-IKTGNAMPLR NIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVAR--DGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVTP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEVAGNR VTQVK----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---SG-VEAGRGLWELRL------ADGEGEGI-----EV---GA-ELNV--G-I-FADVAKVDVTGQSKGKGFQGGVKRW NFRT-QDMTHGNSLSHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDVERN---------------- ----------LLLVKGA-VPGATNGDLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGG---VK-GP----IW---- RGGGVTFAAK-T-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LVVVESF----SVE-A------ --PKTKLIV--TAEVD--E---NLFLAARNLYKVD-V---------------RDVAGLDPVSLIAFNT----VLVTADAV KQIEAKLHDKYQETV----VAELTKKFGYTSVMQVPRIEKITLNMGVG-EAVADKKVMEHAVRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSA-KAFDGRGNYAMGVREQIIFPEID-----YDKI DKIRGMDIVITTS-----------------------ANTDEEGRALLDAFNFPFMSRVA-K--APVSIPAGVEVT-L--- -N-E--Q-TLTVKGAKGSLTRVI--NN-A--VNVVIED-GV--IKF----L-P--VEGVGAW-AQAGTTRALVNNMVVGV SQGFERKLKLVGVGY--RAKLVG-AD--IDLT--LGFSHPLVHKL-P-A-GVTAECP--S-QTDIVLRG-VDKQLIGQVA AEIRGYR------PPEPY---KGKGVRYDDEEVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-A-------KAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-NNLQ-PIGTRIF GPVTRELR-NEQFMKIVSLAPEVLMR-L--NTLSPAAGA-KHAPKRVG-RGMGSGL-GKTAGRGHKGQKSRSGGG-V--- -RPGF-E-GGQMPLKIRLPK-FG--FTSVRVLELIDLNALKDA-NVITAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------TFGLKAV--GRGRLTARQIE SARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--NG-- VSEVIAREAFALAAAKLPIKTTF-VKKTSRLRRAIRARKKI----QELGVNRLVVHRTPRHIYAQVINP---E---AQVV AAASTV-EKAV-KEQL----KST-GNVDAAKAVGKFVAER--AIEKG-VTSVAFDRSGFKYH--GRVAALADAAREAGLQ F--------------------------------------------------------------ME-VLAKHRFARTSAQK ARLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDAAKIRRQDEVIVLAGK------DK-GKR AKVAQVLPT-G--KLI--VEGINLVKKHQK----PN--PQLGVA-GGIVEKEAPIQASNVA-IFNPVT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLNSDWEVRKYL--ADKLQ-----AASVSKIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEVLRAAVSKLAQ INIAEIRK---PELDAKLVADSIAQQLERRVMFRRAMKRAVQNAMRI-GAQGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTSESHTQYGVIGIKVWIFMSMQDPIADMLTRIRNGQAANKVSVKM-PSAKLKVAIAKLLKEEGYIADYA VAD----E--------AKPELEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIV STSKGLMTDRAARLAGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLIS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVTSNKMDKTITVAIERQVKHPIYG KYIKRTTKIHAHDEA--NQCNEGDVVAIRECRPLSKTKSWTLVEVVSKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shewanella_woodyi_ATCC_51908 Concatenation of 2 sequences MAIIKCKPTSAGRRHVVKVVNTD-LHKG------------KP-FAGLLAKKSKSGGRNNTGRITVRH-VGGGHKQH---- YRIIDFK-R--IK-DGIPAKVERLEYDPNRTANIALVLYA-DGERRYILAAKGMQAGDKIQSGI-D-AE-IKVGNALPLR NIPVGSVVHAVEMKPGKGAQIARSAGTYVQVVAR--DGEYATLRLRSGEMRKVPVDCRATMGEVGNAEHMLRQLGKAGAK -RWR-----GVR-P-TVRGVAMNPIDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR --------------------------------MAI---G-LIGRKVGMTRIFT-EDGA---------SIPVTVIEIAANR VTQVR----TLE----T--DGY--RALQVTT-------GT--KITK----------PEAGHFK----------------- ---AG-VEAGRGLWEVRL------ADDEGEGI-----EV---GA-ELNV--D-I-FADVAKVDVTGQSKGKGFQGGIKRW NFHA-QDMTHGNSLAHRS-NGSIGQN-QTPG-RVFKGKKMSGHMGAERVTTQNLDVVRVDAERN---------------- ----------LLLVKGA-VPGATNGNLIIK--MELVLKD-AQ-----SALEVSETTF----GR-DF-NEALVHQVVVAYA ANARQGTRAQKTRAE--------VV-GSGKKPW---------RQKGTGRAR--------AGT---VK-GP----IW---- RGGGVTFAAK-A-QDHSQKVNKKMYRGALKSIFSELVRQD----------------R-LIVVESF----GVE-A------ --PKTKLIV--TPEID--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFNK----VLVTADAV KQIEAKLHDKYQETV----SPELQKKFGFTSVMQVPRIEKITLNMGVG-EAVADKKVMEHALRDMTAIAGQKPVVTVARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGMST-KSFDGRGNYAMGVREQIIFPEIQ-----YDKI DKIRGMDIVITTS-----------------------AKNDEEGRALLEAFNFPFMSRVA-K--APVAIPAGVEVT-L--- -N-E--Q-TITVKGTKGSLTRVI--NT-D--VIVVVED-NE--IKC----S-S--VEGVKTN-AQAGTARALINNMVVGV TEGFEKKLQLIGVGY--RAKIAG-NG--VDLT--LGFSHPLVHEL-P-D-GVSAVCP--S-QTEIVLTG-TDKQLVGQVA AEIRGYR------PPEPY---KGKGVRYADEQVRRKEAK----------MIQMQSTLDVACNSGARRVQCIKVLG-SHRR Y--AGIGDIIKVSVKEAIPR-G-------KAKKGDVYSAVVVRTKKGVRRPDGSVIRFDRNAAVLLN-ANNA-PIGTRIF GPVTRELR-TEQFMKIVSLAPEVLMR-L--NTLSPAAGS-KSAAKRVG-RGIGSGT-GKTCGRGHKGQKSRSGGG-V--- -RIGF-E-GGQMPLKIRLPK-FG--FTSVRISELVDLSTLKDA-NLVTAK---------IVL--SGT-I-E-R-P-VTV- KGLKVTKGARAAIEAAGGKI-K---MFK--GRN---RGLA--NGTEVSFG----------DFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGQIWIRVFPDKPITSKPLEVRMGKGK---------GNVEYWVCQIQP-GKVLYEM--DG-- VSEELAREAFALAAAKLPLKTTF-VKKTSRLRRALRGRKKI----QELGVNRLVVHRTPRHTYAQVISP---D---SQVL ASASTA-EKAV-TEQL----KYT-GNVDAAKVVGKTVAER--AIEKG-VTVVAFDRSGFKYH--GRVAALADAAREAGLK F--------------------------------------------------------------ME-VLAKHRFARTSPQK CRLVADQIRGLPVAKALEILTFS---------------------------------PKKAAVLVKKVLDSAIAN----A- EHNE-GADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDAAKIRREDEVVVLAGK------DK-GKR AKVSQVLPT-G--KLI--VEGVNLVKKHQK----PN--PQLGVA-GGIVEQEAPIQASNVA-IFNSAT-------GK--A --DRVGFRL----E--------DGKVR---FFKSNS---ELV--MGQKVHPNGIRLG--IT-KPWISTWYA------DKS D--YANNLTSDWEVRKFL--EKNLK-----QASVSKIVIERPA-K-SVRVTIHTARPGVVIGKKGEDVEKLRNAVAKLAQ INIAEIRK---PELDAKLVAEGIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYSTAESHTQYGVIGVKVWVFMSMQDPIADMLTRIRNGQAAKHVSVTM-PSAKLKIAIAKTLKEEGYITDYA VAD----E--------AKPVLEITLKYF----QG-------Q---PVVETIQRVSRPGLRIYKGKDELPKVMGGLGVAIV STSKGLMTDRTARQNGMGGEVICYVAMQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILTS PHVNKDAR-DQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVLSNKMDKSITVAIERKVKHPLYG KFLKRTTKIHAHDEQ--NQCNAGDVVTIRECRPLSKTKSWTLVEVVTKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAME---AGDKK----PIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFSPTRTYRGHA------A---DK----KAK------KR >GAMMA_Shigella_boydii_CDC_3083-94 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Shigella_boydii_Sb227 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Shigella_dysenteriae_Sd197 Concatenation of 2 sequences MAAVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----AV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Shigella_flexneri_2a_2457T Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLQKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVQVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--IEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Shigella_flexneri_5_8401 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLQKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKSARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVQVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -------------------------------------------------------------------------------- ------------------------------------------ >GAMMA_Shigella_sonnei_Ss046 Concatenation of 2 sequences MAVVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-FAPLLEKNSKSGGRNNNGRITTRH-IGGGHKQA---- YRIVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKPGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVAR--DGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA -RWR-----GVR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKAGMTRIFT-EDGV---------SIPVTVIEVEANR VTQVK----DLA----N--DGY--RAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------AEGEEF-----TV---GQ-SISV--E-L-FAEVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQMGNERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGSDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---IK-SP----IW---- RSGGVTFAAR-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLHKVD-V---------------RDATGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKKLMTEFNYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDEEGRALLAAFDFPFMSRVA-K--APVVVPAGVDVK-I--- -N-G--Q-VITIKGKNGELTRTL--ND-A--VEVKHAD-NT--LTF----G-P--RDGADGW-AQAGTARALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--INLS--LGFSHPVDHQL-P-A-GITAECP--T-QTEIVLKG-VDKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-SEKFMKIISLAPEVLMR-L--NTLSPAEGS-KKAGKRLG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSDLVDLNTLKAA-NIIGAK---------VIL--AGE-V-T-T-P-VTV- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLAVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKFARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KYT-GNKDAAAAVGKAVAER--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALDILTYT---------------------------------NKKAAVLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNVA-IFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KPWNSTWFA------NTK E--FADNLDSDFKVRQYL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKAAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------TKPELELTLKYF----QG-------K---AVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVV STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Sodalis_glossinidius_morsitans Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLETLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGEQIQSGV-D-AA-IKAGNALPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGAYVTLRLRSGEMRKIQSECRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGIQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MK---G-LIGRKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----DLE----N--DGY--RAIQVTA-------GT--KVIK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRV--------EDGEEV-----TV---GQ-SITV--E-L-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGQLGNERVTVQSLDVVRVDVERN---------------- ----------LLLVKGA-VPGATGGDLIVK--MELVLKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGSRGQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------SGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVEQF----SVK-A------ --PKTKLII--TGELD--E---NLFLAARNLYKVD-V---------------RDANGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEA----VSQLMKQFGYHSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLTAISGQKPLITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFDRLISIAVPRIRDFRGLSA-KSFDGRGNYSMGVHEQIIFPEID-----YDKV DRVRGMDITITTT-----------------------AKSDDEGRALLTAFNFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTI--HE-A--VDVQHAD-NQ--LSF----A-P--REGANGW-ALAGTTRALLNGMVIGV TDGFTKKLQLVGVGY--RAAVKG-NV--VNLS--LGFSHPIDHQL-P-A-GITAECP--S-QTEIVLKG-ADKQIIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLTVADNSGARRVMCIKVLG-SHRR Y--AGVGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVVRFDGNACVLLN-NNSEQPIGTRIF GPVTRELR-TEKFMKIISLAPEVLMR-L--NTLSPAEGS-KHASKRPG-RGIGSGL-GKTGGRGHKGQKSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSIRLSDLVDLNTLKAA-NIVGAK---------IML--SGE-V-K-R-A-VTI- RGLRVSKGARAAIEAAGGKI-K---MHK--GRN---RGLA--VGTDVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRAV------KRQGKIWIRIFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEELAREAFKLAAAKLPIKTTF-VKKAARIRRATRARRKL----QELGATRLVVHRTPRHIYAQVIAP---N--GSEVL VAASTV-EKAI-AEQL----KGT-GNKDAAAAVGKTIAVR--ALEKG-IKDVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAQHRHARSSAQK VRLVADLIRGKKVSQALEVLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVAKIFVDAGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KAI--VEGINLIKKHQK----PV--PAMNQP-GGIVEKEAAIDLSNLA-IFNAAA-------SK--A --DRVGFKI----E--------DGKVR---VFKSNG---ETI--MGQKVHPNGIRLG--IV-KPWNSTWYA------NTK E--FADNLDSDFKVRQFL--TKELS-----KASVSRLVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSISSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKTAVSM-PSSKLKVAIANLLKEEGFIEDYK VEG----D--------TKPTLELVLKYF----QG-------K---PVVETIQRISRPGLRIYKKKDALPKVMAGMGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSIVVAIERFVKHPIYG KFIKRTTKLHVHDEN--NDSNIGDIVEISECRPISKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIRTWSRRSTIFPTMIGLTIAVHNGRQHVPVFVAD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Stenotrophomonas_maltophilia_K279a Concatenation of 2 sequences MPLMKFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALVESQSRSGGRNHHGRITVRH-VGGGAKQH---- YRIIDFK-R--NK-LGIPARVERIEYDPNRTAHIALLCYV-DGERRYIIAPKGLKAGDQVIAGS-D-AP-IKAGNTLPLR NIPVGTTIHCIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECCATIGEVGNDEHSLEKLGKAGAK -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-HNKRTQQ---FIVRDR --------------------------------YSL---G-FVGRKAGMSRVFT-EDGR---------SIPVTLIEATPNR IAQIK----TVE----T--DGY--SAVQVTV-------GA--RVNK----------PEAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAQLGDF-----AV---GG-EVKA--D-I-FEVGQIVDVQGVTKGKGFQGTIKRH NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAVRGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSDAVF----GR-DF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKQYRAAMCAILSELNRQG----------------R-LTIVESF----DVE-V------ --TNTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVSLVGADT----VVITADAV KKVESRLEKFYKDEV----VPALMKQFGYTNPMEVPKLVKVTLNMGVG-EAATNKKILENAVGDMTKISGQKPVVTKSRV SVASFKIRDGWPIGCKTTLRRHKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAITTT-----------------------AKTDAEAKALLAAFKFPFMSRVA-K--KPIDL-GKVELN-V--- -QSD----SVTAKGPKGTLSLAK--PA-G--IAINVDN-GV--ATL------S--TENADLV-ALTGTVRAILSNMVKGV SEGFERKLELVGVGY--RAAMQG-KD--LSLS--LGFSHPVVFVA-P-E-GITLSTP--T-QTEILVQG-ADKQVVGEVA AKIRAFR------KPEPY---KGKGVKYSDEVIIRKEAK----------MIQMQSYLDVADNSGAKQVMCFKVLG-SKRR Y--AGIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRADGSLIRFDGNAAVLLN-SKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLLR-L--NELSPAPGA-RTERTRVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLLYALIDFAALRAA-KLVPAK---------VVV--KGE-V-T-K-A-FTL- KGIAATAGAKAAIEAAGGSV-K---VHK--GRN---DGLS-WSANAVSFG----------EYGLKAT--AHGQLTARQIE AARRSISRYV------KRGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- VSEEVAREAFRLAAAKLSVTTTF-VKNIARLRRAKSTRAHI----RELGVARLSVLRTGQHLYAQVFTA---D--GSKVL AAANTT-QTDV-MEGL----KNG-KNADAAAKVGRIVAER--AKAAG-VEKVAFDRSGYRYH--GRIKALAEAAREAGLQ F-------------------------------------------------------------TME-AKAILRTARISPQK ARLVADQVRGLPAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVQTIMVDEGPTLKRFMARAKGRGTRILKRTSHITVVVGAANRIKKGDQVVVNAGK------DK-GKQ GEVVRVDGD----RVV--VANVNIVKRHTK----PN--PQAGVA-GGVVEREASIHISNVN-VLNPAS-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPIGIRLG--IS-KDWNSKWYA------NKA E--FAGYLAADLKVREML--RKKLA-----QAGISKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSEMAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVGGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGIKVWIYMSMTDPIADLLVRIKNAAAVGKQTVKA-PSSKIKVAIAQVLKDEGYITDLR VTQ---LE---N----NKSELEIVLKYF----EG-------K---PVIATLKRFSRSGLRQYRGKSELPKVMNGLGISII STSKGIMTDAQARQLGVGGEVLCFVAMADQKIRIRLKAFDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTVLVS PHVDKDAR-DQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLLRTVEGRVVSNKMDKTVTVLVERQVKHALYG KYIKRSTKLHAHDAD--NACKEGDVVRVTEIAPMSKTKNWRVVEVITRA------------------------------- -MARSL-KKGPFVDH-HLVKKVEAA-----AGSKK----PIKTWSRRSMILPDMVGVTIAVHNGKNHIPVLVNE-NMVGH KLGEFAITRTFKGHG------G---DK----KSG------K- >GAMMA_Stenotrophomonas_maltophilia_R551-3 Concatenation of 2 sequences MPLMKFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALVESQSRSGGRNHHGRITVRH-VGGGAKQH---- YRIIDFK-R--NK-LGIPARVERIEYDPNRTAHIALLCYV-DGERRYIIAPKGLKAGDQVIAGS-D-AP-IKAGNTLPLR NIPVGTTIHCIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECCATIGEVGNDEHSLEKLGKAGAK -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-HNKR-TQ-Q-FIVRDR --------------------------------YSL---G-FVGRKAGMSRVFT-EDGR---------SIPVTLIEATPNR IAQIK----TVE----T--DGY--SAVQVTV-------GA--RVNK----------PEAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAQLGDF-----AV---GG-EVKA--D-I-FEVGQIVDVQGVTKGKGFQGTIKRH NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAVRGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSDAVF----GR-DF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKQYRAAMCAILSELNRQG----------------R-LTIVESF----DVE-V------ --TNTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVSLVGADT----VVITADAV KKVESRLEKFYKEEV----VPALMKQFGYTNPMEVPKLVKVTLNMGVG-EAATNKKILENAVGDMTKISGQKPVVTKSRI SVASFKIRDGWPIGCKTTLRRHKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAITTT-----------------------AKTDAEAKALLAAFKFPFMSRVA-K--KPIDL-GKVELN-V--- -Q-N--D-NVTAKGPKGTLSLAK--PA-G--IAINVEN-GV--ATL------S--TESVDLI-PLTGTVRAILSNMVKGV SEGFERKLELVGVGY--RAAMQG-KD--LSLS--LGFSHPIVFVA-P-E-GITITTP--T-QTEILVQG-ADKQVVGEVA AKIRAFR------KPEPY---KGKGVKYSDEVIIRKEAK----------MIQMQSYLDVADNSGAKQVMCFKVLG-SKRR Y--AGIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRADGSLIRFDGNAAVLLN-SKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLLR-L--NELSPAPGA-RTERTRVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLLYALIDFAALRAA-KLVPAK---------VVV--KGE-V-T-K-A-FTL- KGIAATAGAKAAIEAAGGSV-K---VHK--GRN---EGLS-WSANAVSFG----------EYGLKAT--AHGQLTARQIE AARRSISRYV------KRGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- VTEDVAREAFRLAAAKLSVTTTF-VKNIARLRRAKSTRAHI----RELGVARLSVLRTGQHLYAQVFTA---D--GSKVL AAANTT-QADI-KDGL----KNG-KNADAAAKVGRIVAER--AKAAG-VEKVAFDRSGYRYH--GRIKALAEAAREAGLQ F--------------------------------------------------------------ME-AKAILRTARISPQK ARLVADQVRGLPAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVQTIMVDEGPTLKRFMARAKGRGTRILKRTSHITVVVGAANRIKKGDQVVVNAGK------DK-GKQ GEIVRVDGD----RVV--VANVNIVKRHTK----PN-PQA-GVA-GGVVEREASIHISNVN-VLNPAS-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPIGIRLG--IS-KDWNSKWYA------NKA E--FAGYLAADLKVREML--RKKLA-----QAGISKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSEMAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVGGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEAKTTYGIIGIKVWIYMSMTDPIADLLVRIKNAAAVGKQTVKA-PSSKIKVAIAQVLKDEGYITDLR VTA---LE---N----NKSELEIVLKYF----EG-------K---PVIATLKRFSRSGLRQYRGKSELPKVMNGLGISII STSKGIMTDAQARQLGVGGEVLCFVAMADQKIRIRLKAFDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTVLVS PHVDKDAR-DQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLLRTVEGRVVSNKMDKTVTVLVERQVKHALYG KYIKRSTKLHAHDAD--NACKEGDVVRVTEIAPMSKTKNWRVVEVITRA------------------------------- -MARSL-KKGPFVDH-HLVAKVAAA-----AGSKR----PIKTWSRRSMILPDMVGVTIAVHNGKNHIPVLVNE-NMVGH KLGEFAITRTFKGHG------G---DK----KSG------K- >GAMMA_Thioalkalivibrio_sp_HL-EbGR7 Concatenation of 2 sequences MPIVKSKPTSAGRRFVVSVVSPD-LHKG------------EP-YAPLVEKKVRSGGRNNQGRITTRH-VGGGHKQR---- YRIIDFK-R--DK-DGIPGRVERLEYDPNRSAHIALVLYA-DGERRYVIAPKGVQAGDQLLSGT-N-AP-IRAGNTLPLR NIPVGTVVHCIEMKPGKGAQMARSAGAAVQLVAR--EGQHATLRLRSGEMRKVPADCRATIGEVSNSEHSLRKFGKAGAK -RWL-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVPTKGYKTR-KNKRTDN---MIVRRR --------------------------------MAI---G-LVGRKLGMTRVFT-EDGA---------SLPVTVIEVDPNR VTQVK----TEE----R--DGY--RALQVTT-------GA--RVTK----------PRAGHFK----------------- ---AG-VEAGRGLWEFRL------DGDQGAEI-----ET---GA-ELKV--D-I-FEAGQIVDVTGISKGKGFQGVIKRH NFSM-QDATHGNSLSHRA-PGSIGQN-QTPG-RVFKGKKMAGHMGNERCTVQNLEVVRVDVERN---------------- ----------LLLIKGA-VPGSTGGNVLVR--MKLQVQD-TK-----KDLEVSDQTF----GR-EF-NEDLVHQAVVAYM AGGRAGTKAQKGRSD--------VS-GGGAKPW---------KQKGSGRAR--------AGT---IR-SP----IW---- RTGGKVFAAR-P-RDYSQKLNRKMYRAAMRSIFSELVRQE----------------R-LVVVDSF----AVD-A------ --PKTKLIV--TDQAD--A---NLYLSARNLPGVD-V---------------SEVGGLDPVSLVGFEK----VLITVPAL KQVEARLKEFYRDTV----MKQLMEKFQYSNVMEVPRITKITLNMGLG-EAVGDKKIIEHAVSDMTAIAGQKPVVTKARK SIAGFKIRDDYPIGCMVTLRREAMYEFLDRLVNVALPRVRDFRGLNP-KGFDGRGNYNMGIKEQIIFPEVD-----YDKI DALRGMNISITTT-----------------------AKNDEEARALLSAFSFPFMSRVA-K--KPIALPSGVNVT-I--- -N-G--N-NVALKGPKGQLSYDL--HA-D--VEVSQEG-NT--LQL----A-P--RNGASKY-AMAGTMRALVNNMVVGV SQGFERKLELVGVGY--RAQAQG-KT--LNLT--LGFSHPVAYPV-P-E-GITIETP--S-QTEILVKG-VDKQVVGQVA AEIRAFR------PPEPY---KGKGVKYANEQIIRKEAK----------MIQMQTVLDAADNSGARKVQCIKVLG-SHRR Y--ASVGDIIKVSVKDAIPR-G-------KVKKGEVYNAVVVRTAKGVRRPDGSVVRFDRNAAVLLN-NQLQ-PIGTRIF GPVTRELR-GEKFMKIISLAPEVLMR-L--NSIAPAPGS-RPSAKRVG-RGIGSGL-GKTAGRGHKGQKARAGGY-H--- -KVGF-E-GGQMPLQRRLPK-VG--FNSVRLHELIDLAALIKA-SVVPAK---------VIA--SGK-L-E-K-A-VTL- KGVAVTKGAREAIEAAGGKI-K---QFT--GKN---RGLA-FSGGKVSFG----------EYALRAQ--DRGRLTARQIE AARRAMTRHI------KRGGKIWIRVFPDVPVTKKPLEVRMGKGK---------GNVEYWVCKVQP-GRILYEM--EG-- VSEEIAREAFKLAAAKLPIKTQF-VKKSARLRRAARTRHQI----RHNGVHRLCVHRTPRHIYAQVIAP---N--GSEVV AAASTV-EVEL-AKDL----KGT-GNVDAAVAIGKVIAER--AKAKG-VSEVAFDRSGFKYH--GRVKALADAAREGGLQ F-------------------------------------------------------------ATE-TFARLRFARISPQK CRLVADQIRGMPVERALQELTFS---------------------------------PKKGAAIVKKVLESAIAN----A- EHNE-GADVDELKVSQIYIDQGPTLKRIHARAKGRANRILKRTSHITVAVGEMQRIKQGDDVIVTAGK------DK-GRR GTVVKVLTD-D--RVV--VQNINMVKKHQK----PN--PTAGQP-GGIIDKEMPIHVSNVM-LFNPAK-------GK--G --DRVGFKT---LE--------DGKVR---YFKSDN---EVV--MGQKVHPVGFRLG--VS-SEWNSTWYA------DGR D--YANVLAKDLEIREFL--KERLS-----QASVSRIEIARPA-R-QAFITIHTARPGIVIGKKGEDIEALRKEAAAKVK INIEEIRK---PEVDAQLVAEGIAQQLERRIMFRRAMKRAVGNAMRL-GALGVKVHVAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEARTTYGVIGVKVWVFMSMTDPVADMLTRIRNGQRASKNEVSM-PASKLKESIAKVLKDEGYIADYG VDA----A---D----GKPVLNIKLKYF----QG-------K---PVIETIKRVSRPGLRIYRSKDELPKVIGGLGVAIV STSNGVMTDRAARALGQGGEVLCIVAMSKQRIRIRLKAFDHRLIDRSASEIVETAKRTGARVKGPIPLPTKMERFTVLIS PHVNKDAR-DQYEIRTHKRLMDIMDPTDKTVDALMKLDLAAGVDVQIKLQRAVIGRVVSDKMDKTRTILIERKVRHPLYG KYIRRSTKLHVHDEG--NEARMGDKVMVQECRPMSKTKTFRLVKVLEKA------------------------------- -MPRSL-KKGPFIDH-HLLQKVDAAVA---NNERR----PIKTWSRRSMIMPQMVGLTIAVHNGRQHVPVLVNE-NMVGH KLGEFAATRTFKGHV------A---NK----KAR-------- >GAMMA_Thiomicrospira_crunogena_XCL-2 Concatenation of 2 sequences MAIIKSKPTSPGRRFVVSVVEPD-LHKG------------KP-FSALLEKKSKSGGRNSNGRITVRH-QGGGHKQH---- YRQIDFK-RN--K-DGVAAVVERLEYDPNRTAHIALLKYA-DGERRYILAPRHVKAGDPVESGE-H-VS-IKAGNALPLR NIPVGTVVHALEMRPGKGAQIARSAGAYAQIAGR--DGAYVLVKLRSGEMRKILADCRATIGEVGNQEHSLRKLGKAGAK -RWK-----GVR-P-TVRGVAMNPVDHPHGGGEGRT-S--GGR-NPVTP---WGVPTKGKKTR-SNKR-TD-R-MIVRRR --------------------------------MGI---G-VIGTKVGMTRVFN-EDGV---------STPVTVVEVSPNR ITQIK----NNE----T--DGY--DAIQVTF-------GS--KVSK----------PEAGHYK----------------- ---AG-VEAGQGLWEFRL-----DDVSEVEGL-----EP---GS-EITV--E-K-FNDVAVVDVSGTTKGKGFQGGVKRH NFKM-QDATHGNSVSHRA-PGSIGQN-QTPG-RVFKGKKMAGHMGNVKQTTLNLELVKVDVENS---------------- ----------LLLIKGA-LPGAKGSTVIVR--MDLKLIELASGKEA-GSVKVSEAIF----GA-EF-NEALVHQVVNAYL AGARSGTKGQKNRSA--------VR-GGGAKPW---------AQKGSGRAR--------AGT---SR-GP----IW---- IGGGRAFPGH-N-RDFSQKVNKKMYRGAMKAIFSELARTE----------------R-LVVVDDF----KVE-A------ --PKTKLVI--TEGFD--E---YLYLSARNLYHAD-V---------------CDVASIDPVSLVGFKS----IVVTQGAI KQLEARLQKIYNDQV----VPALVEKFGYKSVMQAPKLTKITINMGVG-EAIGDKKILDNAVSDMEAITGQKPVKTLARR SVASFKVRDGYPLGCKVTLRGAKMYEFLDRLINVALPRVRDFQGVKG-NAFDGRGNYNLGVKEQIIFPEIE-----FEKV DKIRGMDINFATT-----------------------ASTNEEAKALLEAFNFPFMSRIA-K--SPITLPSGVDVT-I--- -N-G--T-DVSVKGSKGALSKTF--NH-A--VSVSLED-GV--VTV----A-P--KNEKNAW-AQAGTARSIINNMVLGV TEGFEKKLQLVGVGY--RAQAQG-KV--LNLT--LGFSHPVNHEL-P-E-GVTVETP--S-QTEIVVKG-ADKQVVGQVA AEIRGYR------PPEPY---KGKGVKYADEYILRKEAK----------MIQMQTVLDVADNSGARKVQCIKVLG-SKRR Y--ASVGDVIKVAVKEAAPR-G-------KVKKGDVFDAVVVRTAQGVRRPDGSKIKFDGNAAVILN-TKLE-PIGTRIF GPVTRELR-NDKFMKIVSLAPEVLMH-L--NTLKPAEGA-KKLAKRKG-RGQGSGN-GKMAGRGHKGQKSRSGGM-P--- -KIGF-E-GGQMPLQRRLPK-VG--FTSIRLDVLIDLPALKAA-NLVSVK---------VIN--SGE-M-K-K-A-VKI- SGLKVTAGAKATIEAAGGSV-K---MHK--GRN---RGLA-NVGNKISFG----------EFGLKAM--ERGRMTSRQIE AARRVMTRKV------KRGAKIWIRVFPDKPITNKPLEVRMGKGK---------GSVEYWVAQVQP-GRVLYEM--QG-- VDEVVAREAFELAAAKLPFKTQF-VKKATRLRRAKKTRAKL----GSQDRARLCVHRTPKHIYAQIISS---D--GSSVV ASCSTV-QADI-KKQV----AFG-GNKEAAELVGKSIAEK--AKAAG-IESVAFDRSGFKYH--GRVQVLADSARENGLQ F--------------------------------------------------------------MQ-VSATHRFARISPQK ARLVADLIRGKDVETAVNILAFS---------------------------------DKKASELMSKVLNSAIAN----A- ENNE-GADIDELKVTEAYVNEGPIMKRMRARAKGRGNRILKRISHITVTVGDMNRLRKGDEVIVIAGK------DK-GKR GSVSQVMQN-G--KLI--VDGINLAKKHVK----PN--PMTGEQ-GGIVSKEMPVDASNVA-LYNPET-------KK--A --DRVGVRV----E--------GDKTR---FFKSNG---KSV--MGQKVHPIGIRLG--IT-KDWNARWYA------DSK N--YSDFLISDIEIRKEL--NEKLK-----HASVSQINIERVA-N-GVRVTIHTARPGVVIGKKGEDIEKLKQALIAKVN INIEEIKK---PELDAKLVAEGIAQQLEKRIQFRRAMKRAVSNAMRL-GAQGIKVNVSGRLNGAEIARAEWYREGRVPL- -HTLRADIDYATFEADTTYGKIGVKVWIFMSMSDPIADMLTRIRNGQIAGHSNVVM-PSSKVKVAVAKVLTGEGYVSSYS VSD----K---N----GKSELSVDLKYF----EG-------Q---PVIEMLKRVSRPGLRVYKNKDELPKVIGGLGVAVV STSKGIMSDRDARKAGIGGEIICYIAMATQNIRIRLKAFDHRLIDQSAREITETAKRTGAQVKGPIPMPTRKERFTVLVS PHVNKDAR-DQYEIRTHKRLLDIVDPTDKTVDALMKLDLAAGVDVQLELARTMQGVVVSNGMDKSVVVMTNRYIKHPKYK KFVRKSTKVMAHDAD--NACGVGDRVTISECTPFSKRKTWSLVSIDEKA------------------------------- -MPRSV-KKGPFVDH-HLVKKVMEAQE---SGNKR----PIKTWSRRSMILPDMIGLTIAVHNGKEHIPVYVSE-NMVGH KLGEFSMTRTYRGHA------A---DK----KSK-------- >GAMMA_Tolumonas_auensis_TA_4,_DSM_9187 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVTPE-LHKG------------KP-FAGLLEEKRKTGGRNNNGRITTRH-IGGGHKQH---- YRLIDFK-R--NK-DGIPAKIERLEYDPNRSANIALVLYA-DGERRYILAPKNLKAGDPIVSGV-D-AP-IKAGNALPMR NIPVGTTVHAVEMKPGKGAQIARSAGASVQILAR--EGAYVTLRLRSGEVRKVLAECRATVGEVGNAEHMLRQLGKAGAN -RWR-----GIR-P-TVRGMAMNPVDHPHGGGEGRN----KGIQ-PVSP---WGTPAKGYRTR-SNKR-TD-K-YIVRRR --------------------------------MTL---G-LVGRKLGMTRVFT-EDGV---------SIPVTVIEVEANR VTQLK----TLE----T--DGY--TAVQVTT-------GV--KLTK----------AEAGHFK----------------- ---AE-VEAGRGLWEFRL------NDGEGADL-----TV---GS-ELKV--D-I-FADVKKADVTGISKGKGFAGVVKRW NFRT-QDMTHGNSRSHRV-PGSIGQN-QSPG-KVFKGKKMAGHLGCERVTVQSLDIVRVDVERN---------------- ----------LLLIKGA-VPGATNGDVIVK--MELVLKD-AQ-----SALQVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGKKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RGGGVTFAAK-P-QDHSQKVNRKMYRGAIQSILSELVRQD----------------R-LVVVEKF----GVD-A------ --PKTKLIV--TPEVE--E---NLFLAARNLYKVD-V---------------RDVTGIDPVSLIAFDK----VLMTADAV KQIEAKLHDTYRQTV----VQELMNQFGYNSVMQVPRIEKITLNMGVG-EALADKKVLENAAGDLAAISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLICISMPRIRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DKVRGLDITITTT-----------------------AKTDEEGRALLAAFSFPFMSRVA-K--APVTIPAGVEVT-L--- -N-G--Q-EIAVKGKNGTLKRIL--NA-A--VIVTKEE-NV--LKF----A-P--QEGTGAD-AQAGTARALVNNMVIGV TTGFERKLVLVGVGY--RAQAKG-KS--VGLA--LGFSHPIDHEL-P-E-GVTAECP--T-QTEIVLKS-ADKAMLGQVA ADIRAYR------SPEPY---KGKGVRYSDEVVRTKEAK----------MIQMQSMLDVADNSGARSVMCIKVLG-SHRR Y--AGVGDIIKVSIKEAIPR-G-------KVKKGDVYNAVVVRTRKGVRRQDGSLIRFDRNAAVLLN-NQHQ-PIGTRIF GPVTRELR-NDKFMKIVSLAPEVLMR-L--NTLSPAAGA-KSAKKRVG-RGIGSGL-GKTGGRGVKGAGSRSGGG-V--- -RAGF-E-GGQMPLKIRMPK-FG--FYSVRLSEVVDLNTLKQA-GVITAK---------IVL--SGN-I-D-R-A-VTV- RGVSVTKGARAAIEAAGGKI-K---VHK--GRN---RGLA-NAGSDVSFG----------TYGLKAV--TRGQLTARQIE AARRAMTRAV------KRQGKIWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLYEM--DG-- VPEETAREAFALAAAKLSVKTTF-VKKAARIRRATKARRKM----LELGATRLVVHRTPRHIYAQVIAA---S--GAEVL ASASTV-ESTI-REQV----KYT-GNADAAAAVGKAIAER--ALAKG-VTTVAFDRSGFQYH--GRVAALAAAAREAGLQ F-------------------------------------------------------------MME-AIAKHRFARTSAQK ARLVADQVRGLPVDRALNLLAFS---------------------------------PKKAAELIKKVLESAVAN----A- EHNE-GADIDTLKVQTIMVDEGPSLKRIRARAKGRADRIVKRTAHITVVVSDAAKIRREDEVIVLTGK------DK-GKR GKVTKVLVEQG--KVI--VEGINVKKKHQK----PV--PALGVA-GGIVSKEAAVDVSNVA-LFNPAT-------GK--G --DRVGFRF----E--------DGKVR---FFKSNG---ELV--MGQKVHPNGIRLG--IT-KPFNSTWYA------NTK E--FADNLHGDFQVRQYL--TKELK-----AASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRKQIASIAQ INIAEVRK---PELDSQLVADSISSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYATSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAAHKVSVSM-PSSKLKVAIANLLKEEGYIADIK VSG----D--------VKPELEIELKYF----QG-------K---PVVELIQRVSRPGLRIYKKRGDLPKIMNGLGIAVV STSKGVMTDRAARKAGMGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTDKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMDKSITVAIERKVKHPMLG KIIVRTTKLHVHDEN--NECKTGDLVEIRECRPLSKTKCWTLVSVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SADKK----PIKTWSRRSMIIPDMIGLTIAVHNGRQHVPVYVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Vibrio_cholerae_M66-2 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKQH---- YRLVDFK-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLQAGDVIQSGP-D-AP-IKAGNAMPMR NIPVGSTIHNVELTPGKGAQLARSAGAYAQLVAR--DGAYVTLRLRSGEMRKVLSEGRATIGEVGNAEHMLRELGKAGAA -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFT-EDGV---------SIPVTVVEVEANR VSQVK----TLE----T--DGY--AAIQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GS-ELTV--E-L-FNEVKKVDVTGTSKGKGFQGAVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGATGGNVIVK--MELMVKG-A------NALTVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVENF----SVE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-V---------------RDVTGIDPVSLIAFDK----VLMTAAAV KQVEAKLHDYYKSSV----VAELTKQFSYTSVMQVPRIEKITLNMGVG-EAINDKKLLENAASDMAIISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWDFLERLISIALPRVRDFRGVNG-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AGTDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EITIKGAKGELTRVF--HN-G--VVIAQED-NQ--LTF----G-P--REGANAW-AQAGTARALVKNMVVGV TEGFTKKLVLKGVGY--RAAMKG-NA--VGLT--LGFSHPVEHEL-P-A-GVKAECP--S-QTEIVLTG-CDKQVVGQVA ADIRSYR------APEPY---KGKGIRYADENVRSKEAK----------MIQMQTMLDAADNSGARSVMCIKVLG-SHRR Y--AHVGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLN-NNSEQPIGTRIF GPVTRELR-NAKFMKIVSLAPEVLML-L--NTLSPAAGS-KHAPKRLG-RGVGSGL-GKTGGRGHKGQKSRSGGK-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLSELVDLNALKAA-NLVTAK---------IVL--SGE-I-N-K-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VQT--GRN---RGLA--KGTEVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEV--DG-- VPEELAREAFRLAARKLPFKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVIAA---N--GSEVI AAASTV-EKAI-REQV----KYT-GNIDAAKAVGKAVAER--ALEKG-VTVVAFDRSGFQYH--GRVAALADSAREAGLK F--------------------------------------------------------------ME-AIAKHNFARISPQK ARLVADQIRGKSVDQALELLTFS---------------------------------NKKAAELVKKVLESAIAN----A- EHNE-GADIDDLRVAKIFVDEGPVMKRIMPRAKGRADRILKRSSHITVVVADAAKIRQNDEVIVLAGK------DK-GKK GKVTKVLAT-G--KVI--VEGINLVKKHQK----PV--PAMGVQ-GGIVEQEAAIDVSNIA-IFNAKT-------GK--A --DRIGFRF----E--------DGKVR---FFKSNN---EIV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTK D--FADNLDGDFKVRQYL--SKELA-----NASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAAVAKIAQ INIAEVRK---PELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTTYGVIGVKVWIFMSMQDPISDMLTRIRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIADFA VEG----E---V-----KAELEITLKYF----QA-------K---PVIEQIKRVSRPGLRVYKKKDELPSVMGGLGVAVV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLIRTQLGRVVSDKMDKSIVVAIERMVKHPIYG KFVKRTTKVHAHDEN--NECGIGDTVEIRECRPLSKTKSWTLVKIVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Vibrio_cholerae_O1_bv_eltor_N16961 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKQH---- YRLVDFK-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGLQAGDVIQSGP-D-AP-IKAGNAMPMR NIPVGSTIHNVELTPGKGAQLARSAGAYAQLVAR--DGAYVTLRLRSGEMRKVLSEGRATIGEVGNAEHMLRELGKAGAA -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFT-EDGV---------SIPVTVVEVEANR VSQVK----TLE----T--DGY--AAIQVTT-------GS--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GS-ELTV--E-L-FNEVKKVDVTGTSKGKGFQGAVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGATGGNVIVK--MELMVKG-A------NALTVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVENF----SVE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-V---------------RDVTGIDPVSLIAFDK----VLMTAAAV KQVEAKLHDYYKSSV----VAELTKQFSYTSVMQVPRIEKITLNMGVG-EAINDKKLLENAASDMAIISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWDFLERLISIALPRVRDFRGVNG-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AGTDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EITIKGAKGELTRVF--HN-G--VVIAQED-NQ--LTF----G-P--REGANAW-AQAGTARALVKNMVVGV TEGFTKKLVLKGVGY--RAAMKG-NA--VGLT--LGFSHPVEHEL-P-A-GVKAECP--S-QTEIVLTG-CDKQVVGQVA ADIRSYR------APEPY---KGKGIRYADENVRSKEAK----------MIQMQTMLDAADNSGARSVMCIKVLG-SHRR Y--AHVGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLN-NNSEQPIGTRIF GPVTRELR-NAKFMKIVSLAPEVLML-L--NTLSPAAGS-KHAPKRLG-RGVGSGL-GKTGGRGHKGQKSRSGGK-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLSELVDLNALKAA-NLVTAK---------IVL--SGE-I-N-K-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VQT--GRN---RGLA--KGTEVSFG----------TFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEV--DG-- VPEELAREAFRLAARKLPFKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVIAA---N--GSEVI AAASTV-EKAI-REQV----KYT-GNIDAAKAVGKAVAER--ALEKG-VTVVAFDRSGFQYH--GRVAALADSAREAGLK F--------------------------------------------------------------ME-AIAKHNFARISPQK ARLVADQIRGKSVDQALELLTFS---------------------------------NKKAAELVKKVLESAIAN----A- EHNE-GADIDDLRVAKIFVDEGPVMKRIMPRAKGRADRILKRSSHITVVVADAAKIRQNDEVIVLAGK------DK-GKK GKVTKVLAT-G--KVI--VEGINLVKKHQK----PV--PAMGVQ-GGIVEQEAAIDVSNIA-IFNAKT-------GK--A --DRIGFRF----E--------DGKVR---FFKSNN---EIV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTK D--FADNLDGDFKVRQYL--SKELA-----NASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAAVAKIAQ INIAEVRK---PELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTTYGVIGVKVWIFMSMQDPISDMLTRIRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIADFA VEG----E--------VKAELEITLKYF---QAK-----------PVIEQIKRVSRPGLRVYKKKDELPSVMGGLGVAVV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLIRTQLGRVVSDKMDKSIVVAIERMVKHPIYG KFVKRTTKVHAHDEN--NECGIGDTVEIRECRPLSKTKSWTLVKIVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Vibrio_fischeri_MJ11 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKIVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-VGGGHKQH---- YRLIDFK-R--TK-DGIPAVVERLEYDPNRSANIALVLFA-DGERRYIIAPKGIQAGDTVQSGV-D-AP-IKAGNCLPLR NIPVGSTVHCVELKPGKGAQIARSAGAYAQIIAR--DGAYVTLRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAT -RWR-----GVR-P-TVRGVAMNPVDHPHGGGEGRT----SGGRHPVSP---WGMPTKGFKTR-KNKS-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRIFT-EEGV---------SIPVTVVEVEANR VSQVK----TVE----T--DGY--NAIQVTC-------GS--KVSK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GA-ELTV--E-V-FNEIKKVDVTGTSKGKGFQGAVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGSTGGNVIVK--MELMVKG-A------DALTVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-A---------------RDVAGIDPVSLVAFDK----VLMTAAAV KQVEAKLHDYYKSSV----VAELTKEFSYTSVMQVPRVEKITLNMGVG-EAINDKKLLENAAADMAIISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLISIALPRVRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTS-----------------------ANTDAEGRALLAAFNFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-EITIKGGKGELTRVL--ND-A--VVVSQED-NT--IVF----G-P--REGTNAW-AQAGTARALVNNMVIGV NEGFTKKLILKGVGY--RAAMKG-NA--VGLT--LGFSHPVEHAL-P-E-GIKAECP--T-QTEIVVTG-CDKQLVGQVA ADLRSYR------QPEPY---KGKGVRYADEIVRTKEAK----------MIQMQSTLDAADNSGARKVMCIKVLG-SHRR Y--AHIGDIIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSIIRFDRNACVLLN-DTTEQPVGTRIF GPVTRELR-NAKFMKIVSLAPEVLMR-L--NTLSPAAGS-KPSKKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RAGF-E-GGQMPLKQRLPK-FG--FTSVRLSELIDLNSLKAA-NVITAK---------VVL--SGE-I-A-T-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VMT--GRN---RGLA--KGTEVSFG----------DFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGQIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEM--NG-- VPEELAREAFRLAARKLPIKTTF-VKKASRIRRATRARRKI----AELCATRLVVHRTPRHTYAQVIAP---N--GSEVI AAASTV-EKAI-REQL----GNT-SNKAAAEAIGKLIAER--AIEKG-ITNVAFDRSGFQYH--GRVAALAESAREAGLK F--------------------------------------------------------------ME-AIAKHRFAGISPQK ARLVADQVRGKSVDQALEILTFS---------------------------------NKKAAVLVKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPIMKRIMPRAKGRADRILKRSSHITIVVADAAKIRRNDEVIVLVGK------DK-GKK GKVTKVLET-G--KVI--VEGINLVKKHQK----PV--PALGQQ-GGIVEKEAAIDASNIA-IYNEAT-------GK--A --DRIGFRF----E--------EGKVR---FFKSNG---ETI--MGQKVHPNGIRLG--IV-KPWNATWFA------SSQ E--FADNLDGDFKVRQYL--TKELK-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAGVAKIAQ INIAEVRK---PELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTQYGVIGVKVWIFMSMQDPISDMLTRVRNGQSANKVAVKM-PSSKLKVAIAALLKAEGYIADFA VEG----D--------IKPELEITLKYF---QAK-----------PVIEQIQRVSRPGLRVYKKNDALPSVMGGLGIAVV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLTS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISL---MQGRVISDKMDKSIVVAIERMVKHPIYG KYIKRTTKLHAHDEN--NECGLGDTVEIRECRPLSKTKSWTLVNIVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PVKTWSRRSMIIPTMINLTIAVHNGRQHVPVFVTE-DMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Vibrio_harveyi_ATCC_BAA-1116 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKHH---- YRVVDFK-R--TK-DGIPATVERLEYDPNRSANIALVLYK-DGERRYILAPKGVNAGDVIQSGV-D-AP-IKAGNTLPMR NIPVGSTVHNVELKPGKGGQLARSAGAYAQIVAR--DGAYVTIRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAS -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGMPTKGFKTR-KNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFT-EDGV---------SIPVTVVEVEANR VSQVK----TLE----T--DGY--AAIQVTA-------GS--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GA-ELTV--E-L-FNETKKVDVTGTSKGKGFQGAVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGSTGGNVIVK--MELMVKG-A------DALTVSETTF----GR-EF-NEALVHQVVVAFA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RTGGVTFAAK-S-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TSEVD--E---NLFLAARNLYKVD-A---------------RDVAGIDPVSLIAFDK----VVMTAEAV KQVEAKLHDYYKSSV----VAELTKQFSYTSVMQVPRIEKITLNMGVG-EAINDKKLLENAAADMATISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLISIALPRVRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----FDKV DRVRGLDITITTS-----------------------AGTDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EITVKGAKGELTRVL--ND-A--VVIAQEE-NN--LTF----G-P--KEGANAW-AQAGTARALVNNMVVGV TEGFTKKLTLKGVGY--RAAIKG-NA--VGLT--LGFSHPVEHEL-P-A-GIKAECP--S-QTEIIITG-CDKQLVGQVA ADIRSYR------QPEPY---KGKGVRYADENVRTKEAK----------MIQMQSMLDAADNSGARSVMCIKVLG-SHRR Y--AHIGDVIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLN-DNTEQPIGTRIF GPVTRELR-GDKFMKIVSLAPEVLMR-L--NTLAPAAGS-KHAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLGELVDLNSLKAA-NIITVK---------VVL--SGE-I-N-K-V-VTV- KGLRVTKGAKAAIEAAGGKI-K---VQT--GRN---RGLA--KGTDVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEM--GG-- VPEELAREAFRLAARKLPFKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVIAA---N--GSEVI AAASTV-EKAI-REQV----KYT-GNVDAAKAVGKAVAER--ALEKG-VTAVAFDRSGFQYH--GRVAALAESAREAGLK F--------------------------------------------------------------ME-AIAKHNFARISPQK ARLVADLIRGKSVDQALEILTFS---------------------------------NKKAAVLVKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADAAKIRRNDEVIVLAGK------DK-GKK GKVTKVLAT-G--KVI--VEGINLVKKHQK----PV--PALGIQ-GGIVEQEAAIDVSNVA-IFNAAT-------GK--A --DRIGFRF----E--------DGKVR---FFKSNN---EIV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTK D--FADNLDGDFKVRQFL--TKELQ-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAAVAKIAQ INIAEVRK---PELDAQLVGDSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTQYGVIGIKTWIFMSMQDPISDMLTRVRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIVDFA VEG----E---A-----KPELEVTLKYF----QA-------K---PVIEQLKRVSRPGLRVYKKKDQLPSVMGGLGIAIV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLKRTQQGRVVSDKMDKSIVVAIERMVKHPIYG KFVKRTTKVHAHDEN--NECGLGDTVEIAECRPLSKTKSWTLVKVLEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLKTWSRRSMIIPSMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Vibrio_parahaemolyticus_RIMD_2210633 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKHH---- YRVIDFK-R--TK-DGIPATVERLEYDPNRSANIALVLYK-DGERRYILAPKGVVAGDVIQSGV-D-AP-IKAGNTLPMR NIPVGSTVHNVELKPGKGGQLARSAGAYAQIVAR--DGAYVTIRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAS -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGMPTKGFKTR-KNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFT-EEGV---------SIPVTVVEVEANR VSQVK----TLE----T--DGY--AAIQVTA-------GS--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----EV---GA-ELTV--E-L-FNETKKVDVTGTSKGKGFQGAVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGATGGNVIVK--MELMVKG-A------DALTVSETTF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TSEVD--E---NLFLAARNLYKVD-A---------------RDVAGIDPVSLIAFDK----VVMTAEAV KQVEAKLHDYYKSSV----VAELTKQFSYTSVMQVPRIEKITLNMGVG-EAINDKKLLENAASDMATISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWDFLERLINIALPRVRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----FDKV DRVRGLDITITTS-----------------------AGTDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EITVKGAKGELTRVL--ND-A--VVIAQEE-NN--LTF----G-P--KEGANAW-AQAGTARALVNNMVVGV TEGFTKKLTLKGVGY--RAAIKG-NA--VGLT--LGFSHPVEHEL-P-A-GIKAECP--S-QTEIVITG-CDKQLVGQVA ADIRSYR------QPEPY---KGKGVRYADENVRTKEAK----------MIQMQSMLDAADNSGARSVMCIKVLG-SHRR Y--AHIGDVIKVTVKEAIPR-G-------KVKKGDVMKAVVVRTRKGVRRPDGSVIRFDRNACVLLN-NTTEQPIGTRIF GPVTRELR-GDKFMKIVSLAPEVLMR-L--NTLAPAAGS-KHAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLAELVDLNSLKAA-NIITVK---------VVL--SGE-I-N-K-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VQT--GRN---RGLA--KGTDVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHV------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEM--GG-- VPEELAREAFRLAARKLPFKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVIAA---N--GSEVI AAASTV-EKAI-REQV----KYT-GNVDAAKAVGKAVAER--ALEKG-VTAVAFDRSGFQYH--GRVAALAESAREAGLK F--------------------------------------------------------------ME-AIAKHNFARISPQK ARLVADLIRGKSVDQALEILTFS---------------------------------NKKAAALVKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADAAKIRRNDEVIVLAGK------DK-GKK GKVTKVLAT-G--KVI--VEGINLVKKHQK----PV--PALGIQ-GGIVEQEAAIDVSNVA-IFNAAT-------GK--A --DRIGFRF----E--------DGKVR---FFKSNG---ETV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTK D--FADNLDGDFKVRQFL--TSELK-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAAVAKIAQ INIAEVRK---PELDAQLVGDSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTQYGVIGIKTWIFMSMQDPISDMLTRVRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIVDFA VEG----E--------AKPELEVTLKYF---QAK-----------PVIEQLKRVSRPGLRVYKKKDELPSVMGGLGIAIV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLKRTQQGRVVSDKMDKSITVAIERFVKHPIYG KFVKRTTKVHAHDEN--NECGIGDTVEIAECRPLSKTKSWTLVKVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTD-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Vibrio_splendidus_LGP32 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKHH---- YRLVDFK-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGVNAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHCVELKPGKGAQLARSAGAYAQIIAR--DGAYVTIRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAS -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGFKTR-KNKR-TD-K-YIVRRR ---------------------------------MI---G-LVGRKVGMTRVFT-EEGV---------SIPVTVVEVEANR ISQVK----TLE----T--DGY--AAIQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----EV---GA-ELNV--E-L-FNEIKKVDVTGTSKGKGFQGAIKRW NFST-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGSTGGNVIVK--MELMVKG-A------DALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----IW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGAMKSILSELIRQE----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-A---------------RDVAGVDPVSLIAFDK----VLMTADAV KQVEAKLHDYYKSSV----VAELTKEFSYTSVMQVPRIEKITLNMGVG-EAINDKKLLENAASDMATISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWEFLERLISIALPRVRDFRGVSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTS-----------------------AGSDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EVTVKGSKGELTRVL--NS-A--VVIAQEE-NN--LTF----G-P--KEGTNAW-AQAGTARALVNNMVVGV TEGFTKKLTLKGVGY--RAAMKG-NA--VGLT--LGFSHPVEHAL-P-E-GIKAECP--S-QTEIVITG-CDKQVVGQVA ADIRSYR------APEPY---KGKGVRYADENVRTKEAK-----------------------------------A-LHRR Y--AHIGDVIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDSNACVLLN-DTTEQPVGTRIF GPVTRELR-NAKFMKIVSLAPEVLMR-L--NTLSPAAGS-KPSKKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGS-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRLAELVDLNSLKAA-NVITVK---------IVL--SGD-L-S-K-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VMT--GRN---RGLA--KGTEVSFG----------EFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGQIWIRVIPDKPSVQKPLEVRQGKGK---------GSAVYWVAQIQP-GKVMYEM--NG-- VPEELAREAFRLAARKLPVKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVISA---N--GSEVI AAASTV-EKAI-REQV----KNT-GNVDAAKAVGKAVAER--ALEKG-VASVAFDRSGFQYH--GRVAALAESAREAGLK F-------------------------------------------------------------MME-ALAKHNFARISPQK ARLVADQIRGKSVDQALEILTFS---------------------------------NKKAAVLVKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPIMKRIMPRAKGRADRILKRSSHITIVVADAAKIRRNDEVIILAGK------DK-GKK GKVTKVLTT-G--KVV--VEGINLVKKHQK----PV--PALGQQ-GGIVEQEAAIDASNVA-VFNAAT-------GK--A --DRIGFRI----E--------DGKVR---FFKSNG---ETV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTN E--FADNLDGDFKVRQFL--TKELQ-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRAAVAKIAQ INIAEVRK---PELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVQVGGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTQYGVIGIKVWIFMSMQDPISDMLTRVRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIVDFA VDS----E---A-----KPELEVTLKYF----QA-------K---PVIEQIKRVSRPGLRVYKNKDSLPTVMGGLGIAVV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLTS PHVNKDAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLQAALNVQISLNRIQQGRVISDKMDKSIVVAIERTVKHPIYG KFIKRTTKVHAHDED--NTCGLGDKVEIAECRPLSKTKSWTLVKVLEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KK >GAMMA_Vibrio_vulnificus_CMCP6 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKQH---- YRVVDFK-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGMQAGDVIQSGV-D-AP-IKAGNTLPMR NIPVGSTIHCVELTPGKGAQLARSAGAYAQLVAR--DGSYVTIRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAS -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFT-EEGV---------SIPVTVVEVEANR VAQVK----TLE----T--DGY--AAIQVTA-------GT--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GS-ELTV--E-L-FNEVKKVDVTGTSKGKGFQGTVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGATGGNVIVK--MELMVKG-A------AALTVSEATF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----LW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-A---------------RDVAGIDPVSLIAFNK----VLMTADAV KQVEAKLHDYYKSSV----VAELTKQFGYTSVMQVPRIEKITLNMGVG-DAINDKKLLENAAADMATISGQKPLITKARK SVAGFKIREGYPIGL--------MWDFMERLISIALPRVRDFRGVNA-KSFDGRGNYSMGVREQIIFPEID-----FDKV DRVRGLDITITTS-----------------------AGTDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EITVKGAKGELSRVI--NN-A--VVIAQEE-NK--LTF----G-P--REGANAW-AQAGTARALVNNMVVGV TEGFTRKLILKGVGY--RAAIKG-NA--VGLT--LGFSHPVEHEL-P-A-GIKAECP--S-QTEIVLTG-CDKQLIGQVA ADIRAYR------APEPY---KGKGIRYADENVRSKEAK----------MIQMQSMLDAADNSGARSVMCIKVLG-SHRR Y--AHIGDVIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLN-NNTEQPIGTRIF GPVTRELR-GDKFMKIVSLAPEVLMR-L--NTLSPAAGS-KHAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRVAELVDLNSLKAA-NVITVK---------IVL--SGE-I-N-K-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VHT--GRN---RGLA--KGTEVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEV--DG-- VPEELAREAFRLAARKLPFKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVIAA---N--GSEVI AAASTV-EKAI-REQV----KYT-GNIEAAKAVGKAVAER--ALEKG-VSTVAFDRSGFQYH--GRVAALADSAREAGLK F--------------------------------------------------------------ME-AIAKHNFARISPQK ARLVADLIRGKSVDQALEILTFS---------------------------------NKKAAVLVKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADAAKIRRNDEVIVLAGK------DK-GKK GKVTKVLAT-G--KVI--VEGINLVKKHQK----PV--PALGIQ-GGIVEQEAAIDVSNVA-IFNAAT-------GK--A --DRIGFRF----E--------DGKVR---FFKSNG---ETV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTK D--FADNLDGDFKVRQFL--TKELS-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRTAVAKIAQ INIAEVRK---PELDAQLVGDSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTTYGVIGIKVWIFMSMQDPISDMLTRIRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIVDFA VEG----E---A-----KPELEVTLKYF----QA-------K---PVIEQLKRVSRPGLRVYKKKDDLPSVMGGLGVAVV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLIRTQLGRVVSDKMDKSIVVAIERMVKHPIYG KFVKRTTKVHAHDEN--NECGIGDTVEIRECRPLSKTKSWTLVKVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Vibrio_vulnificus_YJ016 Concatenation of 2 sequences MAIVKCKPTSAGRRHVVKVVNAD-LHKG------------KP-YAPLLEKNSKNGGRNNNGRITVRH-IGGGHKQH---- YRVVDFK-R--TK-DGIPAKVERLEYDPNRSANIALVLYA-DGERRYIIAPKGMQAGDVIQSGV-D-AP-IKAGNTLPMR NIPVGSTIHCVELTPGKGAQLARSAGAYAQLVAR--DGSYVTIRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGAS -RWR-----GVR-P-TVRGVVMNPVDHPHGGGEGRT----SGGRHPVSP---WGVPTKGYKTR-SNKR-TD-K-YIVRRR ---------------------------------MI---G-LIGRKVGMTRVFT-EEGV---------SIPVTVVEVEANR IAQVK----TLE----T--DGY--AAIQVTA-------GT--KVNK----------AEAGHFK----------------- ---AG-VEAGRGLWEFRL--------ENGEEF-----AV---GS-ELTV--E-L-FNEVKKVDVTGTSKGKGFQGTVKRW NFRT-QDMTHGNSLSHRA-PGSIGQC-QTPG-RVFKGKKMAGHMGAERVTTQNLEIVRVDAERN---------------- ----------LLLIKGA-VPGATGGNVIVK--MELMVKG-A------AALTVSEATF----GR-EF-NEALVHQVVVAYA AGARQGTRAQKTRSE--------VS-GGGAKPW---------RQKGTGRAR--------AGT---IR-SP----LW---- RTGGVTFAAK-P-QDHSQKVNKKMYRGAMKSILSELVRQE----------------R-LIVVDNF----SVE-A------ --PKTKLIV--TGEVD--E---NLFLAARNLYKVD-A---------------RDVAGIDPVSLIAFNK----VLMTADAV KQVEAKLHDYYKSSV----VAELTKQFGYTSVMQVPRIEKITLNMGVG-DAINDKKLLENAAADMATISGQKPLITKARK SVAGFKIREGYPIGCKVTLRGERMWDFMERLISIALPRVRDFRGVNA-KSFDGRGNYSMGVREQIIFPEID-----FDKV DRVRGLDITITTS-----------------------AGTDEEGRALLAAFNFPFMSRVA-K--APVAIPAGVEVK-L--- -N-G--Q-EITVKGAKGELSRVI--NN-A--VVIAQEE-NK--LTF----G-P--REGANAW-AQAGTARALVNNMVVGV TEGFTRKLILKGVGY--RAAIKG-NA--VGLT--LGFSHPVEHEL-P-A-GIKAECP--S-QTEIVLTG-CDKQLIGQVA ADIRAYR------APEPY---KGKGIRYADENVRSKEAK----------MIQMQSMLDAADNSGARSVMCIKVLG-SHRR Y--AHIGDVIKVTVKEAIPR-G-------KVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLN-NNTEQPIGTRIF GPVTRELR-GDKFMKIVSLAPEVLMR-L--NTLSPAAGS-KHAPKRVG-RGIGSGL-GKTGGRGHKGQKSRSGGK-V--- -RPGF-E-GGQMPLKQRLPK-FG--FTSVRVAELVDLNSLKAA-NVITVK---------IVL--SGE-I-N-K-A-VTV- KGLRVTKGAKAAIEAAGGKI-K---VHT--GRN---RGLA--KGTEVSFG----------SFGLKAV--GRGRLTARQIE AARRAMTRHI------KRQGKIWIRVFPDKPITEKPLEVRQGKGK---------GNVEYWVAQIQP-GKVMYEV--DG-- VPEELAREAFRLAARKLPFKTTF-VKKASRIRRATRARRKI----AELGATRLVVHRTPRHVYAQVIAA---N--GSEVI AAASTV-EKAI-REQV----KYT-GNIEAAKAVGKAVAER--ALEKG-VSTVAFDRSGFQYH--GRVAALADSAREAGLK F--------------------------------------------------------------ME-AIAKHNFARISPQK ARLVADLIRGKSVDQALEILTFS---------------------------------NKKAAVLVKKVLESAIAN----A- EHNE-GADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADAAKIRRNDEVIVLAGK------DK-GKK GKVTKVLAT-G--KVI--VEGINLVKKHQK----PV--PALGIQ-GGIVEQEAAIDVSNVA-IFNAAT-------GK--A --DRIGFRF----E--------DGKVR---FFKSNG---ETV--MGQKVHPNGIRLG--IV-KPWNATWFA------NTK D--FADNLDGDFKVRQFL--TKELS-----KASLSRIVIERPA-K-SIRVTIHTARPGVVIGKKGEDVEKLRTAVAKIAQ INIAEVRK---PELDAQLVGDSIASQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARSEWYREGRVPL- -HTLRADIDYATSSAHTTYGVIGIKVWIFMSMQDPISDMLTRIRNGQAANKVAVKM-PSSKLKVAIAALLKAEGYIVDFA VEG----E--------AKPELEVTLKYF---QAK-----------PVIEQLKRVSRPGLRVYKKKDDLPSVMGGLGVAVV STSKGLMSDRAARKAGLGGEIICYVAMQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKKAR-DQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLIRTQLGRVVSDKMDKSIVVAIERMVKHPIYG KFVKRTTKVHAHDEN--NECGIGDTVEIRECRPLSKTKSWTLVKVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PLKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTE-EMIGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Xanthomonas_axonopodis_pv_citri_306 Concatenation of 2 sequences MPLMKFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALLDSQSKSGGRNHHGRITVRH-VGGGHKQH---- YRIIDFK-R--NK-EGIPARVERIEYDPNRTAHIALLCYV-DGERRYIIAPKGLKAGDQVIAGA-N-AP-IKTGNTLPLR NIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAK -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-KNKRTQQ---FIVRDR --------------------------------YSL---G-FVGRKAGMSRVFT-EDGR---------SVPVTLIEATPNR IAQIK----TVE----V--DGY--SAVQVTV-------GA--RVNK----------PAAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAQLGDF-----AV---GG-EIKA--D-I-FEVGQKVDVQGVTKGKGFQGTIKRY NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAIRGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSDAVF----GR-EF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKMYRAAICAIFSELNRQG----------------R-LMIVDAF----DLE-A------ --TKTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVALVGADT----VVITADAV KKVETRLEKFYKDNV----VPALMKEFGYTNPMEVPKLVKVTLNMGVG-EAATNKKILENAVADMAKISGQKPVVTKSRV SVASFKIRDGWPIGCKTTLRRAKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAITTT-----------------------AKTDAEAKALLAAFKFPFMSRVA-K--KPVSLPKGVELN-V--- -QPG----LVSVKGPKGTLTLPK--PA-G--VEIAIDG-GV--ATL------S--ANDPSQI-ALTGTVRAILANMVKGV SEGFERKLELVGVGY--RAAMQG-KD--LSLA--LGFSHPLVFVA-P-E-GITLSTP--T-QTEIVVQG-ADKQRVGEVA AKIRGFR------PPEPY---KGKGVKYAGEVIIRKEAK----------MIQMQSYLDVADNSGAKEVMCIKVLG-SKRR Y--AHIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRPDGSLIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLLR-L--NDLKPADGA-RTERTRVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLSYQLVDFAALRAA-NLVPAK---------IVL--KGE-L-S-K-K-FVL- KGVAATAGAKAAIEAAGGSV-K---MHK--GRN---DGLA-WSGNAVSFG----------EYGLKAT--AHGQLTARQIE AARRTISRHV------KKGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- IPEETAREAFRLAAAKLSVTTTF-VKNIARLRRAKSTRAHI----RELGVARLSVLRTGQHLYAQVFTA---D--GSKVI AAANTL-QADV-KDGL----KNG-KNSDAAAKVGKLIAER--AKAAG-IEKVAFDRSGYRYH--GRIKALADAAREGGLQ F-------------------------------------------------------------TME-AKAILRTARISPQK ARLVADQVRGLSAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVVVGAANRIKKGDQVVINTGK------DK-GKQ GEVVRVDGD----RVI--VSNANVIKRHTK----PN-PQA-GVA-GGVVEREASIHISNVN-IVNPAT-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPTGIRLG--IA-KDWNSKWYA------NKA E--FASYLAADLKVREML--RKKLA-----QAGVSKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSELAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEASTTYGIIGIKVWIYMSMTDPIADLLVRIKNAAAVGKQTVKL-PSSKIKVAIAQVLKDEGYITDLR VTQ---AE---N----NKAELEIVLKYF----EG-------R---PVIETLKRFSRSGLRQYRGKTELPKVLGGLGIAII STSKGIMTDAQAREAGVGGEVLCFVAMSEQKIRIRLKAFDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTILVS PHADKDAR-DQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLLRTVEGRVVSNKMDKTVTVLVERQVKHALYG KYIKRSTKLHAHDAD--NACNEGDVVRVTEIAPMSKTKNWRVVEIVTRS------------------------------- -MARSL-KKGPFVDH-HLAKKVESA-----AGSKK----PIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNE-NMVGH KLGEFAVTRTFKGHG------G---DK----KSG------R- >GAMMA_Xanthomonas_campestris_pv_campestris_8004 Concatenation of 2 sequences MPLMKFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALLDSQSKSGGRNHHGRITVRH-VGGGHKQH---- YRIIDFK-R--NK-EGIPARVERIEYDPNRTAHIALLCYV-DGERRYIIAPKGLKAGDQVIAGA-N-AP-IKTGNALPLR NIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAK -RRR-----GVR-P-TVRGAAMNANDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-KNKRTQQ---FIVRDR --------------------------------YSL---G-FVGRKAGMSRVFT-EDGR---------SVPVTLIEATPNR IAQIK----TVE----V--DGY--SAVQITV-------GA--RVNK----------PAAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAQLGDF-----AV---GG-EIKA--D-I-FEVGQKVDVQGVTKGKGFQGTIKRY NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAIRGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSDAVF----GR-EF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKMYRAAICAIFSELNRQG----------------R-LMIVDSF----DIE-A------ --TKTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVALVGADT----VVITADAV KKVETRLEKFYKENV----VPALMKEFGYTNPMEVPKLVKVTLNMGVG-EAATNKKILENAVADMSKISGQKPVVTKSRV SVASFKIRDGWPIGCKTTLRRAKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAITTT-----------------------AKTDAEAKALLAAFKFPFMSRVA-K--KPVSLPKGVELN-V--- -Q-P--E-LISVKGPKGTLTLQK--PV-G--VEIAIDG-DV--ATL----S-A--ND-PSQI-AITGTVRAILANMIKGV SEGFERKLELVGVGY--RAAMQG-KD--LSLA--LGFSHPLVFVA-P-E-GITLSTP--T-QTEILVQG-ADKQRVGEVA AKIRGFR------PPEPY---KGKGVKYAGEVIIRKEAK----------MIQMQSYLDVADNSGAKEVMCIKVLG-SKRR Y--AHIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRPDGSLIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLMH-L--NDLKPADGA-RTERTRVG-RGIGSGL-GKTCGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLSYQLIDFAALRAA-NLVPAK---------IVL--KGE-L-S-K-K-FVL- KGVAATAGAKAAIEAAGGSV-K---MHK--GRN---DGLA-WSGNAVSFG----------EYGLKAT--AHGQLTARQIE AARRTISRHV------KKGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- IPEDIAREAFRLAAAKLSVTTTF-VKNIARLRRAKSTRAHI----RELGVARLSVLRTGQHLYAQVFTA---D--GSKVI AAANTL-QADV-KDGL----KNG-KNSDAAVKVGKLIAER--AKAAG-IEKVAFDRSGYRYH--GRIKALADAAREGGLQ F-------------------------------------------------------------TME-AKAILRTARISPQK ARLVADQVRGLSAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVVVGAANRIKKGDQVVINTGK------DK-GKQ GEVVRVEGD----RVI--VSNANVIKRHTK----PN--PQAGVA-GGVVEREASIHISNVN-IVNPAT-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPTGIRLG--IA-KDWNSKWYA------SKA D--FAAYLAADLKVREML--RKKLA-----QAGISKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSEMAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEASTTYGIIGIKVWIYMSMTDPIADLLVRIKNAAAVGKQTVKL-PSSKIKVAIAQVLKDEGYITDLR VTA---TE---N----NKSELEIVLKYF----EG-------R---PVIETLKRFSRSGLRQYRGKTELPKVLGGLGIAII STSKGIMTDAQAREAGVGGEVLCFVAMADQKIRIRLKAFDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTILVS PHADKDAR-DQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLLRTVEGRVVSNKMDKTVTVLVERQVKHPLYG KYIKRSSKLHAHDAD--NACNEGDVVRVTEIAPMSKTKNWRVVEIVTRA------------------------------- -MARSL-KKGPFVDH-HLAKKVESA-----AGSKK----PIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNE-NMVGH KLGEFAVTRTFKGHG------G---DK----KSS------R- >GAMMA_Xanthomonas_campestris_pv_campestris_ATCC_33913 Concatenation of 2 sequences MPLMKFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALLDSQSKSGGRNHHGRITVRH-VGGGHKQH---- YRIIDFK-R--NK-EGIPARVERIEYDPNRTAHIALLCYV-DGERRYIIAPKGLKAGDQVIAGA-N-AP-IKTGNALPLR NIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAK -RRR-----GVR-P-TVRGAAMNANDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-KNKR-TQ-Q-FIVRDR --------------------------------YSL---G-FVGRKAGMSRVFT-EDGR---------SVPVTLIEATPNR IAQIK----TVE----V--DGY--SAVQITV-------GA--RVNK----------PAAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAQLGDF-----AV---GG-EIKA--D-I-FEVGQKVDVQGVTKGKGFQGTIKRY NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAIRGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSDAVF----GR-EF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKMYRAAICAIFSELNRQG----------------R-LMIVDSF----DIE-A------ --TKTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVALVGADT----VVITADAV KKVETRLEKFYKENV----VPALMKEFGYTNPMEVPKLVKVTLNMGVG-EAATNKKILENAVADMSKISGQKPVVTKSRV SVASFKIRDGWPIGCKTTLRRAKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAITTT-----------------------AKTDAEAKALLAAFKFPFMSRVA-K--KPVSLPKGVELN-V--- -Q-P--E-LISVKGPKGTLTLQK--PV-G--VEIAIDG-DV--ATL----S-A--ND-PSQI-AITGTVRAILANMIKGV SEGFERKLELVGVGY--RAAMQG-KD--LSLA--LGFSHPLVFVA-P-E-GITLSTP--T-QTEILVQG-ADKQRVGEVA AKIRGFR------PPEPY---KGKGVKYAGEVIIRKEAK----------MIQMQSYLDVADNSGAKEVMCIKVLG-SKRR Y--AHIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRPDGSLIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLMH-L--NDLKPADGA-RTERTRVG-RGIGSGL-GKTCGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLSYQLIDFAALRAA-NLVPAK---------IVL--KGE-L-S-K-K-FVL- KGVAATAGAKAAIEAAGGSV-K---MHK--GRN---DGLA-WSGNAVSFG----------EYGLKAT--AHGQLTARQIE AARRTISRHV------KKGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- IPEDIAREAFRLAAAKLSVTTTF-VKNIARLRRAKSTRAHI----RELGVARLSVLRTGQHLYAQVFTA---D--GSKVI AAANTL-QADV-KDGL----KNG-KNSDAAVKVGKLIAER--AKAAG-IEKVAFDRSGYRYH--GRIKALADAAREGGLQ F-------------------------------------------------------------TME-AKAILRTARISPQK ARLVADQVRGLSAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVVVGAANRIKKGDQVVINTGK------DK-GKQ GEVVRVEGD----RVI--VSNANVIKRHTK----PN--PQAGVA-GGVVEREASIHISNVN-IVNPAT-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPTGIRLG--IA-KDWNSKWYA------SKA D--FAAYLAADLKVREML--RKKLA-----QAGISKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSEMAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEASTTYGIIGIKVWIYMSMTDPIADLLVRIKNAAAVGKQTVKL-PSSKIKVAIAQVLKDEGYITDLR VTA---TE---N----NKSELEIVLKYF----EG-------R---PVIETLKRFSRSGLRQYRGKTELPKVLGGLGIAII STSKGIMTDAQAREAGVGGEVLCFVAMADQKIRIRLKAFDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTILVS PHADKDAR-DQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLLRTVEGRVVSNKMDKTVTVLVERQVKHPLYG KYIKRSSKLHAHDAD--NACNEGDVVRVTEIAPMSKTKNWRVVEIVTRA------------------------------- -MARSL-KKGPFVDH-HLAKKVESA-----AGSKK----PIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNE-NMVGH KLGEFAVTRTFKGHG------G---DK----KSS------R- >GAMMA_Xanthomonas_oryzae_pv_oryzae_KACC10331 Concatenation of 2 sequences MPLMKFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALLDSQSKSGGRNHHGRITVRH-VGGGHKQH---- YRIIDFK-R--NK-EGIPARVERIEYDPNRTAHIALLCYV-DGERCYIIAPKGLKAGDQVIAGA-N-AP-IKTGNTLPLR NIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAK -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-KNKR-TQ-Q-FIVRDR --------------------------------YSL---G-FVGRKAGMSRIFT-EDGR---------SVPVTLIEATPNR IAQIK----TVE----V--DGY--SAVQITV-------GA--RVNK----------PAAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAHLGDF-----AV---GG-EIKA--D-I-FEVGQKVDVQGVTKGKGFQGTIKRY NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAIHGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSEAVF----GR-EF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKMYRAAICAIFSELNRQG----------------R-LMIVDAF----DLE-A------ --TKTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVALVGADT----VVITADAV KKVETRLEKFYKENV----VPALMKEFGYTNPMEVPKLVKVTLNMGVG-EAASNKKILENAVADMSKISGQKPVVTKSRV SVASFKIRDGWPIGCKTTLRRAKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAVTTT-----------------------AKTDAEAKALLAAFKFPFMSRVA-K--KPVSLPKGVELN-V--- -Q-S--E-LVSVKGPKGTLTLPK--PT-G--VEIAIDG-DV--ATL------S--ANDPSQI-AITGTVRAILANMVKGV SEGFERKLELVGVGY--RAAMQG-KD--LSLA--LGFSHPLVFVA-P-E-GITLSTP--T-QTEILVQG-ADKQRVGEVA AKIRGFR------PPEPY---KGKGVKYAGEVIIRKEAK----------MIQMQSYLDVADNSGAKEVMCIKVLG-SKRR Y--ARIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRADGSLIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLLR-L--NDLKPADGA-RTQRTRVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLSYQLVDFVALRAA-NLVPAK---------IVL--KGE-L-S-K-K-FVL- KGVAATAGAKAAIEAAGGSV-K---MHK--GRN---DGLA-WSGNAVSFG----------EYGLKAT--AHGQLTARQIE AARRTISRHV------KKGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- IPEETAREAFRLAAAKLSVTTTF-V-----------------------------MLRTGQHLYAQVFTA---D--GSKVI AAANTL-QADV-KDGL----KNG-KNSDAAVKVGKLIAER--AKAAG-IEKVAFDRSGYRYH--GRIKALADAAREGGLQ F-------------------------------------------------------------TME-AKAILRTARISPQK ARLVADQVRGLSAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVIVGAANRIKKGDQVVINTGK------DK-GKQ GEVVRVDGD----RVI--VSNANLIKRHTK----PN--PQAGVA-GGVVEREASIHISNVN-IVNPAT-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPTGIRLG--IS-KDWNSKWYA------NKG D--FAAYLAADLKVREML--RKKLA-----QAGVSKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSELAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEASTTYGIIGIKVWIY--------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------LRTVEGRVVSNKMDKTVTVLVERQVKHALYG KYIKRSTKLHAHDAD--NACNEGDVVRVTEIAPMSKTKNWRVVEIVTRS------------------------------- -MARSL-KKGPFVDH-HLAKKVESA-----AGSKK----PIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNE-NMVGH KLGEFAVTRTFKGHG------G---DK----KSS------R- >GAMMA_Xanthomonas_oryzae_pv_oryzae_PXO99A Concatenation of 2 sequences M---KFKPTSPGRRSAVRVVTPD-LHKG------------AP-HAALLDSQSKSGGRNHHGRITVRH-VGGGHKQH---- YRIIDFK-R--NK-EGIPARVERIEYDPNRTAHIALLCYV-DGERCYIIAPKGLKAGDQVIAGA-N-AP-IKTGNTLPLR NIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAR--EGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAK -RWR-----GVR-P-TVRGAAMNPVDHPHGGGEAKA-G--QGNPHPVTP---WGVPTKGYKTR-KNKRTQQ---FIVRDR -----------------------------------------MGRKAGMSRIFT-EDGR---------SVPVTLIEATPNR IAQIK----TVE----V--DGY--SAVQITV-------GA--RVNK----------PAAGHFK----------------- ---AK-VEAGRGLWEFRV------EDAHLGDF-----AV---GG-EIKA--D-I-FEVGQKVDVQGVTKGKGFQGTIKRY NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVQQSTQNLEVVKVDVERG---------------- ----------LIAIHGA-VPGAAGGDVIVR--MELVITG-SN-----NKVSVSEAVF----GR-EF-SEDLVHQVVVAYR NAGRAGTKAQKTRSE--------VA-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVTFAAK-P-RSFEQKVNRKMYRAAICAIFSELNRQG----------------R-LMIVDAF----DLE-A------ --TKTKLIV--TEEAS--E---HLYLSARNLPYVQ-V---------------RDVQGLDPVALVGADT----VVITADAV KKVETRLEKFYKENV----VPALMKEFGYTNPMEVPKLVKVTLNMGVG-EAASNKKILENAVADMSKISGQKPVVTKSRV SVASFKIRDGWPIGCKTTLRRAKMYEFLDRLINISLPRVRDFRGVSG-RSFDGRGNFNMGVKEQIIFPEID-----FDAV DAIRGMDIAVTTT-----------------------AKTDAEAKALLAAFKFPF---------MTLPKPTGVEIA-I--- -D-G--D-V----------------------ATLSAND--------------P--SQI-----AITGTVRAILANMVKGV SKGFERKLELVGVGY--RAAMQG-KD--LSLA--LGFSHPLVFVA-P-E-GITLSTP--T-QTEILVQG-ADKQRVGEVA AKIRGFR------PPEPY---KGKGVKYAGEVIIRKEAK-------------MQSYLDVADNSGAKEVMCIKVLG-SKRR Y--ARIGDIIKVTVKDAIPR-G-------KVKKGEVYDAVVVRTRKGVRRADGSLIRFDGNAAVLLN-NKQE-PIGTRIF GPVTRELR-SEKFMKIVSLAPEVLLR-L--NDLKPADGA-RTQRTRVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KAGF-E-GGQTPMQRRLPK-IG--FRSVLSYQLVDFVALRAA-NLVPAK---------IVL--KGE-L-S-K-K-FVL- KGVAATAGAKAAIEAAGGSV-K---MHK--GRN---DGLA-WSGNAVSFG----------EYGLKAT--AHGQLTARQIE AARRTISRHV------KKGGKMWIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- IPEETAREAFRLAAAKLSVTTTF-VKNIARLRRAKSTRSHI----RDLGVARLSVLRTGQHLYAQVFTA---D--GSKVI AAANTL-QADV-KDGL----KNG-KNSDAAVKVGKLIAER--AKAAG-IEKVAFDRSGYRYH--GRIKALADAAREGGLQ F--------------------------------------------------------------ME-AKAILRTARISPQK ARLVADQVRGLSAERAVNLLKFS---------------------------------DKKAAHLIKKVVESAIAN----A- ENNQ-GADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVIVGAANRIKKGDQVVINTGK------DK-GKQ GEVLRVDGD----RVI--VSNANLIKRHTK----PN--PQAGVA-GGVVEREASIHISNVN-IVNPAT-------GK--G --ERVGFKV---LE--------DGKLR---VFRSSG---EAL--MGHKVHPTGIRLG--IS-KDWNSKWYA------NKG D--FAAYLAADLKVREML--RKKLA-----QAGVSKILIERPA-K-TARVTIHTARPGVVIGKRGEDIEKLRKEVSELAH INVTEVRK---PELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRL-GALGIKVNVAGRLNGAEIARSEWYREGRVPL- -HTLRADIDYGFAEASTTYGIIGIKVWIY------------------------MKL-PSSKIKVAIAQVLKDEGYITDLR VTA---TE---N----NKSELEIVLKYF----EG-------R---PVIETLKRFSRSGLRQYRGKTDLPKVLGGLGIAII STSKGIMTDAQAREAGVGGEVLCFVASEKQKIRIRLKAFDHRLIDRWASEIVETAKRTGAQVRGPIPLPTKIERYTILVS PHADKDAR-DQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLLRTVEGRVVSNKMDKTVTVLVERQVKHALYG KYIKRSTKLHAHDAD--NACNEGDVVRVTEIAPMSKTKNWRVVEIVTRS------------------------------- -MARSL-KKGPFVDH-HLAKKVESA-----AGSKK----PIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNE-NMVGH KLGEFAVTRTFKGHG------G---DK----KSS------R- >GAMMA_Xylella_fastidiosa_9a5c Concatenation of 2 sequences MPLIKFKPTSPGRRSAARVVTPN-IHKG------------SP-HAALLEPQSKTGGRNHHGRITVRH-IGGGCKQR---- YRVIDFK-R--DK-EAIPARVERIEYDPNRTAHIALLCYV-DGERCYIIAPKGLKEGDKIISGP-N-VP-IKLGNSLPLR NIPVGTTVHAVELKPSKGAQMARSAGSSVQLVAR--EGVYATLRLRSGEMRRVLAECRATIGEVGNEEHNLRKLGKAGAK -RWL-----GVR-P-TVRGAAMNPVDHPHGGGEAKS-G--QGNPHPVTP---WGVPTKGYKTR-KNKRTQQ---FIIRGR --------------------------------M-----G-FVGRKAGMSRVFL-EDGC---------SIPVTLIEATANR VVQIK----TSD----V--DGY--DAVQVTV-------GS--RVNK----------PESGHFK----------------- ---AK-VEAGRGLWEFRV------EKTQLGSY-----SV---GS-EVGL--S-I-FAVGQKVDIQGITKGKGFQGTIKRH NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVRQSVQNLEVVKIDVERC---------------- ----------LIAVRGA-IPGASGGDVLIR--MDLTIVG-SD-----NTLPVSDVVF----GR-EF-SEALVHQIVVAYR NTARSGTKAQKSRSQ--------VS-GTTKKSK---------KQKGGG-AR--------HGA---LT-AP----IF---- VGGGVAFAAK-P-RSFSQKVNRKQYRSAICSIFSELNRQG----------------R-LKVVDAF----DVE-V------ --SKTKLIV--SDGIS--E---CLSLSSRNLPCVD-V---------------RSVQALDPVALVGSDV----VVLTVGAV KKIETRLENMYKKEV----VPALIKRFGYSNPMAVPRLVKITLNMGVG-EAATNKKVLENAVADMAKISGQRPIVTKSRI SVASFKIRNGWPIGCKTTLRRSKMYEFLDRLINISLPCVRDFRGIPP-RSFDGRGNFNMGVKEQVVFPEID-----FDAV DAIRGMDIAITTT-----------------------ANSDAEAKALLDAFNFPFMSRVA-K--KPISVPKGVEVS-V--- -R-S--D-MLTVKGVKGVLTFPK--SD-N--VNVVVDG-DI--LTL----S-A--ND-PSHV-SLAGTVRAILSNMIKGV SIGFERKLELVGVGY--RASMQG-EN--LNLS--LGFSHPLVFVP-P-E-GITLLTP--S-QTEVVVQG-IDKQRVGEVA AKIRSFR------PPEPY---KGKGLKYAAEAIMRKEAK----------MIQMQSYLGVADNSGAKEVMCIKVLG-SKRR Y--ASIGDIIKVTVKEAIPR-G-------KVKKGEVYDAVVVRTRSGVRRPDGSLIRFDGNAAVLLN-NKQE-PIGTRVF GPVTRELR-SEKLMKIVSLAPEVLLR-L--NDLKPALGA-SSCRARVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KPGF-E-GGQTPMQRRLPK-IG--FRSVLSYKLIDFASLRLA-KLVPAK---------IVK--KGR-L-T-K-V-FVL- KGIESTAGARAMIETTGGSF-K---MHK--GRN---CGLS-WNANVVSFG----------QYGLRAT--AHGQLTARQIE AARRSISRYV------KRGGKLLIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- VSEDVAREAFRLAASKLSVTTAF-V-----MRRAKSTRVHI----RKLGVPRLSVLRTGRHLYAQIFTA---D--GSKVI AAANTL-QSQV-KDGL----KNG-KNSLAATKVGKLIAER--AKAVG-VDRIAFDRSGYLYH--GRIKILADAARDAGLK F--------------------------------------------------------------ME-ATAILRGARISPQK ARLVAAQVRGLSAESAVNILRFS---------------------------------SKKAACLIKKVVESAIAN----A- ENNH-GSNIDALKINTIIVDEGRMLKRFMARAKGRSSRIVKRSSHITVVVGPASRIKKGDQVIVIAGK------DK-GKQ GEIIRIDGH----RVV--VSNVNIVKRHTK----PN-PQR-SIS-GGLIDREAPIHVSNIQ-VLNPMT-------GK--G --DRVGFKI---LD--------DGKLR---IFRSTG---EVI--MGHKVHPIGIRLG--IS-ADWNSKWYA------NKA E--FAGYLAADLKVRQVL--RKKMS-----QAGISKILIERPS-N-TACVSMHVARPGVVIGKRGEDIEMLRKQVSDIVH INVIEVRK---PELDAQLVAESVAQQLERRIMFRRAMKRSVGNAMRL-GALGIKISVAGRLNGAEIARSEWYREGRVPL- -QTLRADIGYGFSEAHTNYGVTGVKVLIYMSMTDPIADMLVRINNAASVGKPNVRF-PFSRVKLAIALVLKHEGYIFDAK VIQ---GD---N----SKSDIEIVLKYF----EG-------R---PVIRILKRVSRSGLRKYCGKAELPKVLGGLGISII STSKGIMIDSKARESGVGGEVLCFVAMADQKIQIRLKAFDCRLIDRSAGEIVETAKRTGAHVRGPIPLPTKIERCTILVS PHADKDAR-DQYETCTYKRVLYIVDPNDKTVDALMKLELAAGVDVQIKLLRTIKGRVISNKMQKTVTVLVERQIKHALYG KYIKRSTKLHAHDAD--DLCNEGDVVLMTEVAPISKTKNWRVVEIVARS------------------------------- -MPRST-KKGPFFDH-HLIKKVESA-----AGSKR----PIKTCSRRSVILPQMVGHTIAIHNGKNYYPVVINE-NMVGH KLGEFSITRVFKGHG------G---DK----KSG------K- >GAMMA_Xylella_fastidiosa_M12 Concatenation of 2 sequences MPLIKFKPTSPGRRSAARVVTPN-IHKG------------SP-HASLLESQSKTGGRNHHGRITVRH-IGGGCKQR---- YRVIDFK-R--DK-EAIPARVERIEYDPNRTAHIALLCYI-DGERCYIIAPKGLKEGDKIISGP-N-VP-IKLGNSLPLR NIPVGTTVHAVELKPRKGAQMARSAGSSVQLVAR--EGVYATLRLRSGEMRRVLAECRATIGEVGNEEHNLRKLGKAGAK -RWL-----GVR-P-TVRGAAMNPVDHPHGGGEAKS-G--QGNPHPVTP---WGVPTKGYKTR-KNKR-TQ-Q-FIIRGR --------------------------------MGCYSMG-FVGRKAGMSRVFL-EDGR---------SIPVTLIEATANR VVQIK----TSD----V--DGY--DAIQVTV-------GS--RVNK----------PESGHFK----------------- ---AK-VEAGRGLWEFRV------EKTQLGSY-----SV---GS-EVGL--S-I-FAVGQKVDIQGITKGKGFQGTIKRH NFRM-GDATHGNSLSHRA-PGSLGQR-QTPG-RVFPGKKMSGHMGAVRQSVQNLEVIKIDVERF---------------- ----------LIAVRGA-IPGASGGDVLIR--MDLTIVG-SD-----NTLPVSDVVF----GR-EF-SEALVHQVVVAYR NTARSGTKAQKSRSQ--------VS-GTTKKSK---------KQKG-GGAR--------HGA---LT-AP----IF---- VGGGVAFAAK-P-RSFSQKVNRKQYRSAICSIFSELNRQG----------------R-LKVVDAF----DVE-V------ --SKTKLIV--SDEIS--E---CLSLSSRNLPCVD-V---------------RSVQALDPVALVGSDV----VVLTVGAV KKIETRLENMYKKEV----VPALIKRFGYSNPMAVPRLVKITLNMGVG-EAATNKKVLENAVADMAKVSGQKPIVTKSRI SVASFKIRNGWPIGCKTTLRRSKMYEFLDRLINISLPCVRDFRGIPP-RSFDGRGNFNMGVKEQVVFPEID-----FDAV DAIRGMDIAITTT-----------------------ANSDAEAKALLDAFNFPFMSRVA-K--KPISIPKGVEVS-V--- -Q-S--D-MLTVKGVKGVLTFPK--SD-N--VNVVMDG-DI--LTL----S-A--ND-PSHI-SLAGTVRAILSNMIKGV SIGFERKLELVGVGY--RASMQG-KD--LNLT--LGFSHPLVFVP-P-E-GITLLTP--S-QTEVVVQG-IDKQRVGEVA AKIRSFR------PPEPY---KGKGLKYAAEAIIRKEAK----------MIQMQSYLGVADNSGAKEVMCIKVLG-SKRR Y--ASIGDIIKVTVKEAIPR-G-------KVKKGEVYDAVVVRTRSGVRRPDGSLIRFDGNAAVLLN-NKQE-PIGTRVF GPVTRELR-SEKLMKIVSLAPEVLLR-L--NDLKPALGA-SSSRARVG-RGIGSGL-GKTAGRGHKGSFARKGGGKI--- -KPGF-E-GGQTPMQRRLPK-IG--FRSVLSYKLIDFASLRLA-KLVPAK---------IVK--KGR-L-T-K-V-FVL- KGIESTAGARAMIETTGGSF-K---MHK--GRN---CGLS-WNANVVSFG----------QYGLRAT--AHGQLTARQIE AARRSISRYV------KRGGKLLIRVFPDKPITKKPIEVRMGSGK---------GNVEYWVAQIQP-GRMIYEI--EG-- VSEDVAREAFRLAASKLSVTTAF-VKNVARLRRAKSTRVHI----RKLGVPRLSVLRTGRHLYAQIFTA---D--GSKVI AAANTL-QSQV-KDGL----KNG-KNSLAATKVGKLIAER--AKAVG-VDRIAFDRSGYLYH--GRIKILADAARDAGLK F-------------------------------------------------------------NME-ATAILRGARISPQK ARLVAAQVRGLSAESAVNLLRFS---------------------------------SKKAACLIKKVVESAIAN----A- ENNH-GSNIDDLKINTIIVDEGRMLKRFMARAKGRSSRIVKRSSHITVVVGPASRIKKGDQVIVIAGK------DK-GKQ GEIIRIDGH----RVV--VSNVNIVKRHTK----PN-PQR-GIS-GGLIDREAPIHVSNIQ-ILNPMT-------GK--G --DRVGFKI---LD--------DGKLR---IFRSTG---EVI--MGHKVHPIGIRLG--IS-ADWNSKWYA------NKA E--FAGYLAADLKVRQVL--RKKMS-----QAGISKILIERPS-N-AACVSMHVARPGVVIGKRGEDIEMLRKQLSDIVH INVIEVRK---PELDAQLVAESVAQQLERRIMFRRAMKRSVSNAIRL-GALGIKISVAGRLNGAEIARSEWYREGRVPL- -QTLRADIGYGFSEAHTNYGVTGVKVLIYMSMTDPIADMLVRIKNAASVGKPNVRF-PFSKVKLAIALVLKHEGYIFDAK VIQ---GD---N----SKSDIEVVLKYF----EG-------R---PVIRILKRVSRSGLRKYCGKAELPKVLGGLGVSII STSKGIMTDSKARESGVGGEVLCFVAMADQKIQIRLKAFDCRLIDRSAGEIVETAKRTGAHVRGPIPLPTKIERCTILVS PHADKDAR-DQYETCTYKRVLYIVDPNDKTVDALMRLELAAGVDVQIKLLRTIKGRVISNKMQKTVTVLVERQIKHALYG KYIKRSTKIHAHDAD--DLCNEGDVVLMTEVAPISKTKNWRVVEIVARS------------------------------- -MPRST-KKGPFFDH-HLIKKVESA-----AGSKR----PIKTCSRRSVILPQMVGHTIAIHNGKNYHPVVINE-NMVGH KLGEFSITRVFKGHG------G---DK----KSG------K- >GAMMA_Yersinia_enterocolitica_enterocolitica_8081 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVLADCRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----SLE----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------PEGQEF-----TA---GQ-EISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGHLGDERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLIVK--MELIVKD-AQ-----SALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIIVEKF----SVE-A------ --PKTKLII--TGELD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKQLMSQFDYNSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFLERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFKFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTV--HS-A--VEVKQEE-NT--LTF----A-P--REGVDGW-AQAGTTRALLNAMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHEL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTAGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSELIDLNTLKAA-NVVGAK---------VML--SGE-I-T-R-A-VTL- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------EFGLKAC--GRCRLTARQIE AARRAMTRAI------KRQGKVWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLFEM--AG-- VPEETAREAFKLAAAKLPVGTTF-VKKAARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEIL VAASTV-EKAI-NEQL----KYA-GNKDAAAAVGKAVAER--ALEKG-ITKVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLAYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSA-S--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNIA-LFNAAT-------GK--A --DRVGFRF----E--------DGKVR---FFKSNS---ETI--MGQKVHPNGIRLG--IV-KAWNSTWYA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQSANKVAVTM-PSSKLKVAIANVLKEEGFIEDFK VEG----D--------AKPVLELALKYF----QG-------K---AVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSMVVAIERVVKHPIYG KFIRRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIRTWSRRSTVFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Yersinia_pestis_bv_Microtus,_91001 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----SLE----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------PEGQEF-----TA---GQ-EISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGHMGDERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLIVK--MELVMKD-AP-----GALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIIVEKF----SVE-A------ --PKTKLIV--TGELD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKQLMSQFGYDSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFKFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTV--HS-A--VEVKQEE-NT--LTF----A-P--REGVDGW-AQAGTTRALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHEL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTAGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSELIDLNTLKAA-NVVGVK---------VIL--SGE-V-N-R-A-VTL- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------EFGLKAC--GRCRLTARQIE AARRAMTRAI------KRQGKVWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLFEM--AG-- VPEETAREAFKLAAAKLPVGTTF-VKKAARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEIL VAASTV-EKAI-NEQL----KYA-GNKDAAAAVGKTIAER--ALEKG-ITKVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNLA-LFNATT-------GK--A --DRVGFRF----E--------DGKVR---FFKSTS---ETI--MGQKVHPNGIRLG--IV-KAWNSTWYA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANVLKEEGFIEDFK IEG----D--------TKPVLELALKYF----QG-------K---AVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSMVVAIERVVKHPIYG KFIRRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIRTWSRRSTVFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Yersinia_pestis_KIM Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----SLE----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------PEGQEF-----TA---GQ-EISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGHMGDERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLIVK--MELVMKD-AP-----GALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIIVEKF----SVE-A------ --PKTKLIV--TGELD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKQLMSQFGYDSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFKFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTV--HS-A--VEVKQEE-NT--LTF----A-P--REGVDGW-AQAGTTRALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHEL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTAGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSELIDLNTLKAA-NVVGVK---------VIL--SGE-V-N-R-A-VTL- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------EFGLKAC--GRCRLTARQIE AARRAMTRAI------KRQGKVWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLFEM--AG-- VPEETAREAFKLAAAKLPVGTTF-VKKAARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEIL VAASTV-EKAI-NEQL----KYA-GNKDAAAAVGKTIAER--ALEKG-ITKVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNLA-LFNATT-------GK--A --DRVGFRF----E--------DGKVR---FFKSTS---ETI--MGQKVHPNGIRLG--IV-KAWNSTWYA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANVLKEEGFIEDFK IEG----D--------TKPVLELALKYF----QG-------K---AVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISL------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------ >GAMMA_Yersinia_pseudotuberculosis_IP_31758 Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----SLE----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------PEGQEF-----TA---GQ-EISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGHMGDERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLIVK--MELVMKD-AP-----GALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIIVEKF----SVE-A------ --PKTKLIV--TGELD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKQLMSQFGYDSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFKFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTV--HS-A--VEVKQEE-NT--LTF----A-P--REGVDGW-AQAGTTRALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHEL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTAGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSELIDLNTLKAA-NVVGVK---------VIL--SGE-V-N-R-A-VTL- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------EFGLKAC--GRCRLTARQIE AARRAMTRAI------KRQGKVWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLFEM--AG-- VPEETAREAFKLAAAKLPVGTTF-VKKAARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEIL VAASTV-EKAI-NEQL----KYA-GNKDAAAAVGKTIAER--ALEKG-ITKVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNLA-LFNATT-------GK--A --DRVGFRF----E--------DGKVR---FFKSTS---ETI--MGQKVHPNGIRLG--IV-KAWNSTWYA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANVLKEEGFIEDFK IEG----D--------TKPVLELALKYF----QG-------K---AVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSMVVAIERVVKHPIYG KFIRRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVVPRKPP------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIRTWSRRSTVFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >GAMMA_Yersinia_pseudotuberculosis_YPIII Concatenation of 2 sequences MAIVKCKPTSPGRRHVVKVVNPE-LHKG------------KP-YAPLLEKLSKSGGRNNNGRITTRH-IGGGHKQH---- YRLVDFK-R--NK-DGIPAVVERLEYDPNRSANIALVLYK-DGERRYILAPKGLKAGDQIQSGV-D-AA-IKAGNTLPMR NIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVAR--DGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGAS -RWR-----GIR-P-TVRGTAMNPVDHPHGGGEGRN----FGKH-PVTP---WGVQTKGKKTR-SNKR-TD-K-FIVRRR ---------------------------------MI---G-LVGKKVGMTRIFT-EDGV---------SIPVTVIEIEANR VTQVK----SLE----N--DGY--RAVQVTT-------GA--KVTK----------PEAGHFK----------------- ---AG-VEAGRGLWEFRL--------PEGQEF-----TA---GQ-EISV--E-I-FADVKKVDVTGTSKGKGFAGTVKRW NFRT-QDATHGNSLSHRV-PGSIGQN-QTPG-KVFKGKKMAGHMGDERVTVQSLDVVRVDAERN---------------- ----------LLLVKGA-VPGATGGNLIVK--MELVMKD-AP-----GALTVSETTF----GR-DF-NEALVHQVVVAYA AGARQGTRAQKTRAE--------VT-GSGKKPW---------RQKGTGRAR--------AGS---VK-SP----IW---- RSGGVTFAAK-P-QDHSQKVNKKMYRGALKSILSELVRQD----------------R-LIIVEKF----SVE-A------ --PKTKLIV--TGELD--E---NLFLAARNLYKVD-V---------------RDVAGIDPVSLIAFDK----VVMTADAV KQVEAKLHDYYKDEV----VKQLMSQFGYDSVMQVPRVEKITLNMGVG-EAIADKKLLDNAAADLAAISGQKPFITKARK SVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSA-KSFDGRGNYSMGVREQIIFPEID-----YDKV DRVRGLDITITTT-----------------------AKSDDEGRALLAAFKFPFMSRVA-K--APVVIPAGVEVK-L--- -N-G--Q-VISIKGKNGELTRTV--HS-A--VEVKQEE-NT--LTF----A-P--REGVDGW-AQAGTTRALLNSMVIGV TEGFTKKLQLVGVGY--RAAVKG-NV--VNLA--LGFSHPVDHEL-P-A-GITAECP--T-QTEIVLKG-ADKQVIGQVA ADLRAYR------RPEPY---KGKGVRYADEVVRTKEAK----------MIQEQTMLNVADNSGARRVMCIKVLG-SHRR Y--AGIGDIIKITIKEAIPR-G-------KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILN-NNSEQPIGTRIF GPVTRELR-NEKFMKIISLAPEVLMR-L--NTLSPAEGA-KHAPKRVG-RGIGSGL-GKTAGRGHKGQNSRSGGG-V--- -RRGF-E-GGQMPLYRRLPK-FG--FTSVRLSELIDLNTLKAA-NVVGVK---------VIL--SGE-V-N-R-A-VTL- RGLRVTKGARAAIEAAGGKI-K---MHK--GRN---RGLA--QGTDVSFG----------EFGLKAC--GRCRLTARQIE AARRAMTRAI------KRQGKVWIRVFPDKPITEKPLEVRMGKGK---------GNVEYWVALIQP-GKVLFEM--AG-- VPEETAREAFKLAAAKLPVGTTF-VKKAARIRRATRARRKL----KELGATRLVVHRTPRHIYAQVIAP---N--GSEIL VAASTV-EKAI-NEQL----KYA-GNKDAAAAVGKTIAER--ALEKG-ITKVSFDRSGFQYH--GRVQALADAAREAGLQ F--------------------------------------------------------------ME-TIAKHRHARSSAQK VRLVADLIRGKKVSQALETLTYT---------------------------------NKKAAGLVKKVLESAIAN----A- EHND-GADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDAAKIRRDDEVIVLTGK------DK-GKR GKVKNVLSS-G--KVI--VEGINLVKKHQK----PV--PALNQP-GGIVEKEAAIQVSNLA-LFNATT-------GK--A --DRVGFRF----E--------DGKVR---FFKSTS---ETI--MGQKVHPNGIRLG--IV-KAWNSTWYA------NTK E--FADNLDSDFKVRQFL--TKELA-----KASVSRIVIERPA-K-SIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAQ INIAEVRK---PELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRL-GAKGIKVEVSGRLGGAEIARTEWYREGRVPL- -HTLRADIDYNTSEAHTTYGVIGVKVWIFMSMQDPIADMLTRIRNGQAANKVAVTM-PSSKLKVAIANVLKEEGFIEDFK IEG----D--------TKPVLELALKYF----QG-------K---AVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVI STSKGVMTDRAARQAGLGGEIICYVAMQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLIS PHVNKDAR-DQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLIRTLQGRVVSDKMEKSMVVAIERVVKHPIYG KFIRRTTKLHVHDEN--NECGIGDVVEIRECRPLSKTKSWTLVRVVEKA------------------------------- -MPRSL-KKGPFIDL-HLLKKVEKAVE---SGDKK----PIRTWSRRSTVFPNMIGLTIAVHNGRQHVPVFVSD-EMVGH KLGEFAPTRTYRGHA------A---DK----KAK------KR >P_Borrelia_afzelii_PKo Concatenation of 2 sequences MGIKTYKPKTSSLRYKTTLSFDD-LSKG------N-----DP-LKSLTKGKKFKSGRDSSGRISIRR-RGGGHKRK---- YRLIDFN-RR-DK-FSIPARVASIEYDPNRSANIALLVYK-DGEKRYIISPKDIKVGDVLESGP-N-AP-IKIGNALPLE NIPIGRTVHNIELNVGKGGQLVRSAGGYAMILAS--DGNYVTVKLSSGEVRLIFKKCIATIGEIGNEDYVNVSIGKAGKS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPTKGYKTR-KKKRYSD-K-FIIKRR ---------------------------------ML---G-LIGKKVGMTQIFQ-KNGI---------VVPVTVIEFQPNY IIGKK----TVD----R--DGY--SALIAGS-------VD--LVSK----------PIKGQYS----------------- ---LKDIEPKKYVIELKG----------LDGY-----DA---GD-EIKV--D-V-FKSVKYVDVTGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGNQQTIQNLEVVLINEEKR---------------- ----------AILVKGA-VPGAKGSFVVVK--MERKVFS-KDGKEI-RTINLDDRVF----NI-EI-SHGSIYNAIKNEL SNLRVGTSSTKTRSE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---RR-NP----VW---- IGGGIALGPK-P-RDYSYRLPKKVKRLAFKSVLSLRASDE----------------NNFKVIENF----NIE-S------ --GKTKVIL--LGNDD--Q---MIKRAGKNIRDLK-I---------------LSFDKLRVVDLFYAKN----LIALESAV NKLNPELKKYYKDSV----IKELVKEFEYKSIMQVPKLEKIVVSIGVG-EAVRNKKLLDSAVLELAQITGQKAVKTKAKK AIAGFKIRQGQEIGAKVTLRGNSMYEFLYKLIHLALPRVKDFRGING-DAFDGNGNYSFGISEQIIFSEID-----YDKI ERISGLNVTIVTT-----------------------ASNDKESKALLLKFGMPFMSRIG-R--LPIKIPDTVKID-V--- -K-D--N-LVIVEGIRGRLVQNI--KD-S--INVKVEN-GS--VIV------GRVFNDKKAK-AYHGLYRSLIFNMIKGV TEGFSKSLTINGIGY--RAEQQG-NS--LFLS--LGYSTQFEYVI-P-D-GVSVKLD--G-NTKISVEG-IDKFKVGQVA AEIRSLK------KPEPY---KGKGIKYDNEIIRRKVGK----------MIQMQTYLTIADNTGGKVAQCIKVLG-SKRR Y--AKIGDIITIVVKQAIPN-S-------SVKKGDVCKAVIVRTSKEVRRKNGTYVRFDDNACVILD-ANLS-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--FSLLKPKGA-AKRRKIVG-RGPGSGL-GKTSGRGQKGQKARNTSP----- -RLGF-E-GGQTPLYRRLPR-KG--FSNVNLGDIVNYDTLLEN-KLIRIK---------ILS--NGK-L-T-K-K-VSL- EVSKISKTAESLVMKIGGTI-K---KQR--GRL---SGEA-QKGNKISFG----------EYGLVSL--ETNFITARQIE AARIAMTRKI------KRGGRVWIRIFPDIPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEM--AG-- VVEELAQEAMSLASSKLPVKTMF-VAEQRKIRRKKRIKDKI--GRGIATRPRITIFKSNRYFYAQVIDD---S--KGHTV ASISTI-EKSL---------NLS-KNIDDIKKLGEVLAKR--LKEKN-INNLIFDRNGYKYH--GLIASFATSLREFGIN I-------------------------------------------------------------NRR-YTAKGKNLPASPKK VRPIADNIRGKSYVKAIAVLCSM---------------------------------PNKGAKLLEKVVKSAASN----AM YHNK-NLSEDMIFIKMVMVDDGRRRKKIWPRARGRADRLVNRNCHIFVEVDEKTKLKIGDSVKILSGK------DK-GRI GKIASINRKKN--KVI--VESCNMVKKVIK----AR--TP-QEK-GKIIDKEAAIDISNVM-IFVK---------GT--S --SRLGIRF---EN--------NEKIR---YLKKNG---QRI--MGQKVHPYSLRVK--IN-KDWKSKWYF------DKK L--YSTILHEDFLIRLEI--MKFLKGI---KFDISDIEIIRNNPQ-KVTVVIVTPRPGSVIGLKGSNLEKIGQLLTKKIS IKIKEVKR---PELDAQIIANGIAKQVENRVSYRKVLKSALSTSMLK-GAQGLKIKIAGRLGGAEIARSFEVKEGRVPL- -HTLRANIDYGFSEAHTTYGIIGVKVWLFMAITHSVGDMLTKLRNASRVKHGSVDL-KMSNMNKSILNILKKEGYIKDFN FLE----K---E----GITFIRVLLKYD---NKR-------N---PVINKIDAISTPGRKIYSSYKNMPRIKNGYGILII SSSQGVITGKEAKDKKIGGELICSVWIAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGRVVSDKMSKTIVVEIVQRKMHPIYH KYLKVSKKVKAHDEK--EVSKVGDKVKIIEVRPISKDKRWSLVEVLEKL------------------------------- -MARSI-KKGPFIEK-SLYQKVLSSFG---SEKRV----VIKTYSRSSTIIPEMVSLTISVYNGKTFIPIYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR-------K >P_Borrelia_burgdorferi_B31 Concatenation of 2 sequences MGIKTYKPKTSSLRYKTTLSFDD-LSKG------N-----DP-LKSLTKGKKFKSGRDSSGRISIRR-RGGGHKRK---- YRLIDFN-RR-DK-FSIPARVASIEYDPNRSANIALLVYK-DGEKRYIISPKGIKVGDVLESGP-N-AP-IKIGNALPLE NIPIGRTVHNIELNVGKGGQLIRSAGGYAMILAS--DGNYVTVKLSSGEMRLIFKKCIATIGEIGNEDYANISIGKAGKS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPTKGYKTR-KKKRYSD-K-FIIKRR ---------------------------------ML---G-LIGKKVGMTQIFQ-KNGI---------VVPVTVIEFQPNY IIGKK----TVD----R--DGY--SALIAGS-------VD--LVSK----------PIKGQYS----------------- ---LKDIEPKRYVIELKG----------LDGY-----DA---GD-EIKV--D-V-FKSVKYVDVTGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGNQQTIQNLEVVLIDEEKR---------------- ----------ALLVKGA-VPGAKGSFVVVK--MERKVFS-KDGKEI-GTINLDDRVF----NI-EI-SHGSIYNAIKNEL SNLRVGTSSTKTRSE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---KR-NP----VW---- IGGGIALGPK-P-RDYSYRLPKKVKKLAFKSVLSLRAADE----------------NSFKVIENF----NVE-S------ --GKTKVIL--LGNDD--Q---MIKRAGKNIRDLK-I---------------LSFDKLRVVDLFYAKN----LIALESAV NKLNPELKKYYKDSV----IKELVKEFEYKSIMQVPKLEKIVISVGVG-EAVRNKKLLDSAVLELAQITGQKAVKTKAKK AIAGFKIRQGQEIGAKVTLRGNAMYEFLYKLIHLALPRVKDFRGING-DAFDGNGNYSFGITEQIIFSEID-----YDKI ERISGLNITIVTT-----------------------ASNDKESKALLLKFGMPFMSRIG-R--LPIKIPDAVKVD-V--- -K-D--N-LVIVEGIRGRLVQDI--KD-S--INVKVEN-GS--VIV------DRVLNDKKAK-AYHGLYRSLIFNMVKGV TEGFSKSLTINGIGY--RVEQQG-NS--LFLS--LGYSTQFEYVI-P-D-GISVKLD--G-NTKISVEG-IDKFKVGQVA AEIRSLK------KPEPY---KGKGIKYDNEVIRRKVGK--------MIVIQMQTYLTIADNTGGKVAQCIKVLG-SKRR Y--AKIGDIITIVVKQAIPN-S-------SVKKGDVYKAVIVRTSKEVRRKNGTYVRFDDNACVILD-ANLS-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--FNLLKPKGA-SKRRKIVG-RGPGSGL-GKTSGRGQKGQKARNTSP----- -RLGF-E-GGQTPLYRRLPR-KG--FSNVNLGDIVNYDTLLEN-KLIKIK---------ILS--NGK-L-T-K-K-VSF- EVSKISKSAESLVIKIGCTI-K---KQR--GRL---SGEA-QKGNKISFG----------EYGLVSL--ETNFITARQIE AARIAMTRKI------KRGGRVWIRIFPDIPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEM--SG-- VVEELAQEAMSLASSKLPVKTMF-VAEQRKLRRKKRIKDKI--GRGVASRPRITVFKSNRYFYAQVIDD---S--KGHTI ASISTI-EKSL---------NLG-KNIDDVKKLGEVLAKR--LKEKN-INNLIFDRNGYKYH--GLIASFATSLREFGIN I-------------------------------------------------------------NRR-YTAKGKNLPSSPKK VRPIADNIRGESYIKAIAVLCSM---------------------------------PNKGAKLLEKVVKSAASN----AM YHNK-NLSEDMIFVKTVMVDDGRRRKKIWPRARGRADRLVNRNCHIFVEVDEKTKLKIGDSVKILSGK------DR-GRI GKIASINRKKN--KVI--VESCNMVKKVIK----AR--TP-QEK-GRIIDKEAAIDISNVM-IFVK---------GT--S --SRLGIRF---EN--------NEKIR---YLKKNG---QRI--MGQKVHPYSLRVK--IN-KDWKSKWYF------DKK L--YSAILHEDFLIRREI--MKFLKGI---KFDISDIEIIRNNPQ-KVTVVIVTPRPGSVIGLKGSNLEKIGQLLTKKIS IKIKEVKR---PELDAQIIANGIAKQVENRASYRKVLKSSLSTSMLK-GAQGLKIKIAGRLGGAEIARSFEVKEGRVPL- -HTLRANIDYGFSEAQTTYGIIGVKVWLFMAITYSIGDMLTKLRNASRVGHGSVDL-KMSNMNKSILNILKEEGYIKDFN FLE----K---K----GIAFIRVLLKYD---NKR-------N---PVINKIDAISTPGRKIYSSYRNMPRIKNGYGILII SSSQGVITGKEAKDKKIGGELICSVWIAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGKVVSDKMSKTIVVEIVQRKMHPIYH KYLKVSKKVKAHDEK--EVSKVGDKVKIIEVRPISKDKRWSLVEVLEKL------------------------------- -MARSI-KKGPFIEK-SLYQKVLSSFG---SEKRV----VIKTYSRSSTIIPEMVSLTISVYNGKTFIPIYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR------K- >P_Borrelia_burgdorferi_ZS7 Concatenation of 2 sequences MGIKTYKPKTSSLRYKTTLSFDD-LSKG------N-----DP-LKSLTKGKKFKSGRDSSGRISIRR-RGGGHKRK---- YRLIDFN-RR-DK-FSIPARVASIEYDPNRSANIALLVYK-DGEKRYIISPKGIKVGDVLESGP-N-AP-IKIGNALPLE NIPIGRTVHNIELNVGKGGQLIRSAGGYAMILAS--DGNYVTVKLSSGEMRLIFKKCIATIGEIGNEDYANISIGKAGKS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPTKGYKTR-KKKRYSD-K-FIIKRR ---------------------------------ML---G-LIGKKVGMTQIFQ-KNGI---------VVPVTVIEFQPNY IIGKK----TVD----R--DGY--SALIAGS-------VD--LVSK----------PIKGQYS----------------- ---LKDIEPKRYVIELKG----------LDGY-----DA---GD-EIKV--D-V-FKSVKYVDVTGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGNQQTIQNLEVVLIDEEKR---------------- ----------ALLVKGA-VPGAKGSFVVVK--MERKVFS-KDGKEI-GTINLDDRVF----NI-EI-SHGSIYNAIKNEL SNLRVGTSSTKTRSE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---KR-NP----VW---- IGGGIALGPK-P-RDYSYRLPKKVKKLAFKSVLSLRAADE----------------NSFKVIENF----SVE-S------ --GKTKVIL--LGNDD--Q---MIKRAGKNIRDLK-I---------------LSFDKLRVVDLFYAKN----LIALESAV NKLNPELKKYYKDSV----IKELVKEFEYKSIMQVPKLEKIVISVGVG-EAVRNKKLLDSAVLELAQITGQKAVKTKAKK AIAGFKIRQGQEIGAKVTLRGNAMYEFLYKLIHLALPRVKDFRGING-DAFDGNGNYSFGITEQIIFSEID-----YDKI ERISGLNITIVTT-----------------------ASNDKESKALLLKFGMPFMSRIG-R--LPIKIPDAVKVD-V--- -K-D--N-LVIVEGIRGRLVQDI--KD-S--INVKVEN-GS--VIV------DRVLNDKKAK-AYHGLYRSLIFNMVKGV TEGFSKSLTINGIGY--RVEQQG-NS--LFLS--LGYSTQFEYVI-P-D-GISVKLD--G-NTKISVEG-IDKFKVGQVA AEIRSLK------KPEPY---KGKGIKYDNEVIRRKVGK----------MIQMQTYLTIADNTGGKVAQCIKVLG-SKRR Y--AKIGDIITIVVKQAIPN-S-------SVKKGDVHKAVIVRTSKEVRRKNGTYVRFDDNACVILD-ANLS-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--FNLLKPKGA-SKRRKIVG-RGPGSGL-GKTSGRGQKGQKARNTSP----- -RLGF-E-GGQTPLYRRLPR-KG--FSNVNLGDIVNYDTLLEN-KLIKIK---------ILS--NGK-L-T-K-K-VSF- EVSKISKSAESLVIKIGCTI-K---KQR--GRL---SGEA-QKGNKISFG----------EYGLVSL--ETNFITARQIE AARIAMTRKI------KRGGRVWIRIFPDIPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEM--SG-- VVEELAQEAMSLASSKLPVKTMF-VAEQRKLRRKKRIKDKI--GRGVASRPRITVFKSNRYFYAQVIDD---S--KGHTI ASISTI-EKSL---------NLG-KNIDDVKKLGEVLAKR--LKEKN-INNLIFDRNGYKYH--GLIASFATSLREFGIN I-------------------------------------------------------------NRR-YTAKGKNLPSSPKK VRPIADNIRGESYIKAIAVLCSM---------------------------------PNKGAKLLEKVVKSAASN----AM YHNK-NLSEDMIFVKTVMVDDGRRRKKIWPRARGRADRLVNRNCHIFVEVDEKTKLKIGDSVKILSGK------DR-GRI GKIASINRKKN--KVI--VESCNMVKKVIK----AR--TP-QEK-GRIIDKEAAIDISNVM-IFVK---------GT--S --SRLGIRF---EN--------NEKIR---YLKKNG---QRI--MGQKVHPYSLRVK--IN-KDWKSKWYF------DKK L--YSAILHEDFLIRREI--MKFLKGI---KFDISDIEIIRNNPQ-KVTVVIVTPRPGSVIGLKGSNLEKIGQLLTKKIS IKIKEVKR---PELDAQIIANGIAKQVENRASYRKVLKSSLSTSMLK-GAQGLKIKIAGRLGGAEIARSFEVKEGRVPL- -HTLRANIDYGFSEAQTTYGIIGVKVWLFMAITYSIGDMLTKLRNASRVGHGSVDL-KMSNMNKSILNILKEEGYIKDFN FLE----K---K----GIAFIRVLLKYD---NKR-------N---PVINKIDAISTPGRKIYSSYRNMPRIKNGYGILII SSSQGVITGKEAKDKKIGGELICSVWIAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGKVVSDKMSKTIVVEIVQRKMHPIYH KYLKVSKKVKAHDEK--EVSKVGDKVKIIEVRPISKDKRWSLVEVLEKL------------------------------- -MARSI-KKGPFIEK-SLYQKVLSSFG---SEKRV----VIKTYSRSSTIIPEMVSLTISVYNGKTFIPIYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR------K- >P_Borrelia_duttonii_Ly Concatenation of 2 sequences MGIKTYRPKTSSLRYKTTLSFDE-LSKG------N-----DP-LKSLTKGKVSRAGRDSSGRISVRR-RGGGHKRR---- YREIDFA-RR-DK-FGIPARVAAIEYDPNRSPNIALLVYR-DGDKRYIIAPKGVKVGDILESGP-N-AP-IKIGNALPLE NIPVGKMVHNIELNIGKGGQLVRGAGGYAMIIAS--DGDYVTVKLPSGEMRMIFKKCIATLGEVGNEDYMNVSIGKAGKS -RWL-----GRR-P-KVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQPAKGYKTR-KKNKYSD-K-FIVKRR ---------------------------------MF---G-LIGKKVGMTQVFQ-SNGI---------VVPVTVIEFEPNY VIGKK----TME----R--DGY--DALIMGS-------VD--LVSR----------PIKGQYK----------------- ---LENIEPKRYVIEFKG---------LK-GY-----DA---GD-EVGL--D-A-FREIKYVDITGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGEQQTIQNLEIVFIDEEKR---------------- ----------AILVKGA-VPGVKGSFVIVK--MERKVFS-KDGQEL-RTIDLDDGVF----NI-DV-SYGSIYNAINNEL ANLRVGTASTKTRAE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---RR-NP----VW---- VGGGIALGPK-P-RDYSYKLPKKVKRLAFKSVLSLCASVD----------------DRLKVVENF----TID-S------ --GKTKVIL--LGNDD--Q---MIKRAGKNIRDLK-I---------------LSFNRLRVVDLFYTKN----LIALESAI NGLNPELKRRYRDNI----VKELVSEFQYKSIMQAPKIEKIVVSMGVG-DAVKNKKLLDSAVMELSQITGQKAVKTKAKK AISGFKIRQGQEIGAKVTLRGNMMYEFLYKLVNLALPRVKDFRGING-NAFDGNGNCSFGIAEQIIFSEID-----YDKI ERISGLNVTIVTT-----------------------ALNDKEGKALLAKFGMPFMSRIG-K--LPIKIADSVKVD-I--- -K-D--N-FITVEGKRGKLSQEI--NS-S--IRVKIED-NN--IIV---ER-A--FNDKQTR-AFHGLYRSLIFNMVKGV SDGFSKSLTINGIGY--RVEQQG-NS--LFFN--LGYSTQFEYVI-P-E-GINIRLD--G-NTKIAVEG-IDKCRVGQVA AEIRSLK------VPEPY---KGKGIKYDNEVIRRKVGK----------MVQMQTYLTVADNTGGKIAQCIKVLG-SKRR Y--AKVGDIIVIAVKQAIPN-S-------PVKKGDVHKAVIIRTSKEIRRKNGTYVRFDDNACVILD-ANLN-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--IKLKRPLGA-NKSKKIVG-RGQGSGL-GKTSGRGQKGQKARNSSP----- -RIGF-E-GGQTPLYRRLPR-RG--FSNVGLGDIVNYDTLFQK-GLVNIK---------ILA--NGE-L-T-K-K-VNF- EISRISKFAEELATKIGCSI-K---KQR--GRL---SGEA-QKGNKISFG----------EYGLVSL--EADFITARQIE AARVAMTRRV------KRGGKVWIRIFPDIPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEM--SG-- VPRELAESAMMLASSKLPVKTTF-VAEKRNIKRKKRIRDRI--GFGVAERPRVTIFKSNKYFYAQVIDD---I--VGHTL ASVSTI-EKEL---------SLN-KNISDVKKLGEVLAKR--LKDKN-ISKLIFDRNGYKYH--GLIAGFATALREAGID V-------------------------------------------------------------NKK-YTAKGKNLPSSPKK VRPIADNIRGKPYNEAVAILCSM---------------------------------PNKGAKLLGKVVKSAASN----AM YHNR-NLSEDMIFVKTVMVDDGRKRRSIWPRARGRADRLINRSCHIFVEVYEKTKLRVGDKVKILCGK------DR-GKV GEIASIDRKKF--KVT--VKSCNMIKKVIK----AR--TP-QEK-GKIIDKEAPMDISNVM-LFSN---------GV--I --SRVGIKF---EN--------NEKKR---YLKKSG---ENV--MGQKVHPYSLRIK--IN-RDWKSKWYF------DKK L--YSEILHEDFLIRRET--MKFLKGI---KFDISDIEIIRNNLQ-RVTVVISTPRPGSVIGVKGANLEKIGQLLTRKIN IKIKEIKK---PEFDAQIVANGIAKQLENRASYRKLLKSSLLSSISK-GIQGIKIKVSGRLGGAEIARSFEVKEGRIPL- -HTLRANIDYGFAEAYTTYGVIGVKVWLFMAVTHSVGDMLTKIRNASRVKHESVDL-KMSKINRSILDILKEEGYIKNYN IFD----K---K----GIPFIKAMLNYD---GKR-------N---PAINRIDAISTPGRKVYSSYKNMPRIKNGYGILIV SSSKGVITGKQAKDNKVGGELICSVWITKDKIRVRLFSFDVKILDQSAESIVRAVQKSKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGKVVSDKMSKTVVVEIVQRKMHPIYH KYLKVSRRVKAHDER--EESKLGDKVKIVESRPISKEKRWRLIEILERS------------------------------- -MARSI-KKGPFIEK-SLYQKVLASSG---KEKRV----VIKTYSRTSTIIPEMVSLTISVYNGKSFIPVYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR-------K >P_Borrelia_garinii_PBi,_OspA Concatenation of 2 sequences MGIKTYKPKTSSLRYKTTLSFDD-LSKG------N-----DP-LKSLTKGKKLKSGRDSSGRISIRR-RGGGHKRK---- YRLIDFN-RR-DK-FSIPARVASIEYDPNRSANIALLVYK-DGEKRYIISPKGIKVGDVLESGP-N-AP-IKIGNALPLE NIPIGRTIHNIELNVGKGGQLVRSAGGYAMILAS--DGNYVTVKLSSGEMRLIFKKCIATIGEIGNEDYANVSIGKAGKS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPTKGYKTR-KKKRYSD-K-FIIKRR ---------------------------------ML---G-LIGKKVGMTQIFQ-KNGI---------VIPVTVIEFQPNY IIGKK----TVD----R--DGY--SALIAGS-------VD--LVSK----------PIKGQYS----------------- ---LKDIEPKKYVIELKG----------LDGY-----DA---GD-EIKV--D-V-FKSVKYVDVTGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGNKQTIQNLEVVLIDEENR---------------- ----------AILVKGA-VPGAKGSFVVVK--MERKVFS-KDGKEI-GTINLDDRVF----NI-EI-SHGSIYNAIKNEL SNLRVGTSSTKTRSE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---KR-NP----IW---- IGGGIALGPK-P-RDYSYRLPKKVKRLAFKSVLSLRAADE----------------NNFKVVENF----NIE-S------ --GKTKVIL--LGNDD--Q---MIKRAGKNIRDLK-I---------------LSFNKLRVVDLFYAKN----LIALESAV NKLNPELKKYYKDSV----IKELVKEFEYKSIMQVPKLEKIVVSVGVG-EAVRNKKLLDSAVLELSQITGQKAVKTKAKK AIAGFKIRQGQEIGAKVTLRGNAMYEFLYKLIHLALPRVKDFRGING-NAFDGNGNYSFGITEQIIFSEID-----YDKI ERISGLNVTIVTT-----------------------ASNDKESKALLLKFGMPFMSRIG-R--LPIKIPDTVKID-V--- -K-G--N-LVIVEGTRGKLVQDI--KD-S--INVKVEN-GS--VIV---NR-A--FNDKKTK-AYHGLYRSLIFNMVKGV TEGFSKSLTINGIGY--RVEQQG-NS--LFLN--LGYSTQFEYVV-P-D-GVSVKLD--G-NTKISVEG-IDKFKVGQVA AEIRSLK------KPEPY---KGKGIKYDNEVIRRKVGK----------MIQMQTYLTIADNTGGKLAQCIKVLG-SKRR Y--AKIGDIITIVVKQAIPN-S-------SVKKGDVCKAVIIRTSKEVRRKNGTYVRFDDNACVILD-ANLS-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--FNLLKPKGA-SKRRKIVG-RGPGSGL-GKTSGRGQKGQKARNTSP----- -RLGF-E-GGQTPLYRRLPR-KG--FSNVNLGDIVNYDTLLEN-KLIRIK---------ILS--NGE-L-T-K-K-VSL- EVSKISKSAESLVIRIGGTI-K---KQR--GRL---SGEA-QKGNKISFG----------EYGLVSL--ETSFITARQIE AARIAMTRKI------KRGGRVWIRIFPDIPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEM--AG-- VIEELAQEAMSLASSKLPVKTMF-VAEQRKLRRKKRIKDKI--GRGVASRPRITIFKSNRYFYAQVIDD---S--RGHTV VSISTI-EKSL---------NLS-KNIDDIKKLGEVLAKR--LKEKN-INNLIFDRNGYKYH--GLIASFATSLREFGIN I-------------------------------------------------------------NRR-YTARGKNLPSSPKK VRPIADNIRGKSYIKAIAVLCSM---------------------------------PNKGAKLLEKVVKSAASN----AM YHNK-NLSEDMIFVKIVMVDDGRRRKKIWPRARGRADRLVNRNCHIFVEVDEKTKLKIGDSVKILSGK------DK-GRI GKIASINRKKN--KVI--VESCNMVKKVIK----AR--TP-QEK-GKIIDKEAAIDISNVI-IFIK---------GT--S --SRLGIRF---EN--------NEKIR---YLKKNG---QRI--MGQKVHPYSLRVK--IN-KDWKSKWYF------DKK L--YSTILHEDFLIRLEI--MKFLKGI---KFDISDIEIIRNNPQ-KVTVVIVTPRPGSVIGLKGSNLEKIGQLLTKKIS IKIKEVKR---PELDAQIIANGIAKQVENRVSYRKVLKSSLSTSMLK-GAQGLKIKIAGRLGGAEIARSFEVKEGRVPL- -HTLRANIDYGFSEAQTTYGIIGVKVWLFMAITYSVGDMLTKLRNASRVKHGSVDL-KMSNMNKSILNILKEEGYIKDFN FLE----K---E----GIAFIKVLLKYD---NKR-------N---PVINKIDAISTPGRKIYSSYKNMPRIKNGYGILII SSSKGVITGKEAKNKKIGGELICSVWIAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGKVVSDKMSKTIVVEIVQRKMHPIYH KYLKVSKKVKAHDEK--EVSKVGDKVKIIEVRPISKDKRWALVEVLEKL------------------------------- -MARSI-KKGPFIEK-SLYQKVLSSFG---SEKRV----VIKTYSRSSTIIPEMVSLTISVYNGKTFIPIYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR------K- >P_Borrelia_hermsii_DAH Concatenation of 2 sequences MGIKTYRPKTSSLRYKTTLSFDE-LSKG------N-----NP-LKSLTRGKVSRAGRDSSGRISVRR-RGGGHKRR---- YREIDFG-RR-DK-FGIPARVVSIEYDPNRSSNIALLVYK-DGDKRYIIAPKGIKVGDILESGP-N-SP-IRIGNALPLE NIPVGKTVHNIELNIGKGGQLVRGAGGYAMVLAS--EGDYVTVKLPSGEMRMIFKKCMATLGEVGNEDYVNVSIGKAGKS -RWL-----GRR-P-KVRGVAMNPVDHPHGGGEGKT-S--GGRH-PVSP---WGQPTKGYKTR-KKKKYSD-K-FIIKRR ---------------------------------ML---G-LIGKKVGMTQVFQ-GNGV---------VVPVTVIEFEPNY IIGKK----TVE----R--DGY--DALIMGS-------VD--LISK----------PIKGQYN----------------- ---LENVEPKKYVIEFKG----------LKGY-----DA---GD-EVGL--D-A-FKEIKYVDITGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGSTGQA-ATPS-RTFKGTKMAGRMGGEQQTIQNLEVVFIDEEKR---------------- ----------AILVKGA-VPGVKGSFVIVKFSMERKVFS-KDGQEL-RTIDLEDRVF----NI-DI-SYGSIYNAINNEL ANLRVGTASTKTRSE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---KR-NP----IW---- VGGGIALGPK-P-RDYSYKLPRKVKRLAFRSVLSLCASAE----------------DRLKIVENF----TIE-S------ --GKTRVIL--LGNDD--Q---MVKRAGRNIRDLK-I---------------LSFNRLRVVDLFYAKN----LIALESAV NGLNPELKRHYKDNV----IKELVSEFQYKSIMQAPKIEKIVVSMGVG-DAVKNKKLLDSAISELSQITGQRAVKTKAKK AIAGFKIRQGQDIGAKVTLRGNIMYEFLYKLINLALPRVKDFRGVDG-NAFDGNGNYSFGIAEQIIFSEID-----YDKI ERISGLNVTIVTT-----------------------ALNDKEGKALLSKFGMPFMSRIG-K--LPIKIVDSVKVD-I--- -N-D--N-IVTVEGKRGKLSQEI--NS-R--IRVRVED-SN--IIV---ER-S--LDDKQTR-AFHGLYRSLIFNMVKGV SDGFSKSLTINGIGY--RVEQQG-TS--LFFN--LGYSTQFEYVI-P-E-GVNIRLE--G-NTKIAVEG-IDKCRVGQVA AEIRSLR------VPEPY---KGKGIRYDNEVSRRKVGK--------MIMVQIQTYLTVADNTGGKIAQCIKVLG-SKKR Y--ARVGDIIVVAVKQAIPN-S-------PVKKGDVHKAVVVRTSKEIRRKNGTYVRFDDNACVILD-ANLN-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--VKLRRPSGA-NKSRKIVG-RGPGSGL-GKTSGRGQKGQKARNSSP----- -RIGF-E-GGQTPLYRRLPR-RG--FSNVGLGDIVNYSTLLEK-GLVGIK---------ILA--NGG-L-T-K-K-VNF- EVTRISKSAEELATKIGCSI-K---KQR--GRL---SGEA-HKGNKISFG----------EYGLVSL--DTYFITARQIE AARVAMTRRV------KRGGKVWIRIFPDVPYTKKPAETRMGKGK---------GGVDHWNAPVKI-GTVMFEM--AG-- VPRELAEAAMMLASSKLPVKTTF-VAEKRNIKRKKRIRDRI--GFGVADRPRVTVFKSNKYFYVQVIDD---M--AGHTL ASVSTI-EKDL---------KLN-KNIDDVKKLGEVLAKR--LKDKN-ISRLIFDRNGYKYH--GLIASFATSLREAGID V-------------------------------------------------------------NRR-YTARGKNLPSSPKK VRPIADNIRGKPYTEAVAILYSM---------------------------------PNKGAKLLGKVVKSAASN----AM YHNR-NLSEDMIFVKTVMVDDGRKRRSIWPRARGRADRLVNRSCHIFVEVYEKTKLKVGDNVKILCGK------DR-GKT GEIVSIDRKNL--KVV--VKSCNMVKKVIK----AR--TP-QEK-SKIIDKEAPVDISNVM-LFSN---------GI--T --SRVGIKF---EN--------KEKKR---YLKKNG---ENV--MGQKVHPYSLRIK--IN-RDWKSKWYF------DKK L--YSEILHEDFLIRRET--MKFFKGI---RFDISDIEIIRNNLQ-RVTVVVSTPRPGSVIGVKGANLEKIGQLLTRKIN IKIKEIKK---PEFDAQIVANGIAKQLENRASYRKLLKSSLLSSISK-GVQGVKIKVSGRLGGAEIARSFEVKEGRVPL- -HTLRANIDYGFAEAQTTYGVIGVKVWLFMAVTHSVGDMLTKIRNASRVKHESVDL-KMSKINKSILDILREEGYIKGYN IFD----N---K----GISFIKAILNYD---SKR-------N---PAINRIDAISTPGRKVYSSYKNMPRIKNGYGILIV SSSKGVITGKQAKDNKVGGELICSVWITKDKIRVRLFSFDVKILDQSAESIVRAVQKSKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKDLIGKVVSDKMSKTIVVEIVQRKMHPIYH KYLKVSRRVKAHDER--EESRLGDKVRIIESRPISKEKRWMLVEILERS------------------------------- -MARSI-KKGPFIEK-SLYQKVLASSG---REKRV----VIKTYSRASTIIPEMVSLTISVYNGKSFIPVYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR-------K >P_Borrelia_recurrentis_A1 Concatenation of 2 sequences MGIKIYRPKTSSLRYKTTLSFDE-LSKG------N-----DP-LKSLTKGKVSRAGRDSSGRISVRR-RGGGHKRR---- YREIDFA-RR-DK-FGIPARVAAIEYDPNRSPNIALLVYR-DGDKRYIIAPKGVKVGDILESGP-N-AP-IKIGNALPLE NIPVGKMVHNIELNIGKGGQLVRGAGGYAMIIAS--DGDYVTVKLPSGEMRMIFKKCIATLGEVGNEDYMNVSIGKAGKS -RWL-----GRR-P-KVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQPAKGYKTR-KKNKYSD-K-FIVKRR ---------------------------------MF---G-LIGKKVGMTQVFQ-SNGI---------VVPVTVIEFEPNY VIGKK----TME----R--DGY--DALIMGS-------VD--LVSR----------PIKGQYK----------------- ---LENIEPKRYVIEFKG---------LK-GY-----DA---GD-EVGL--D-A-FREIKYVDITGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGEQQTIQNLEIVFIDEEKR---------------- ----------AILVKGA-VPGVKGSFVIVK--MERKVFS-KDGQEL-RTIDLDDGVF----NI-DV-SYGSIYNAINNEL ANLRVGTASTKTRAE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---RR-NP----VW---- VGGGIALGPK-P-RDYSYKLPKKVKRLAFKSVLSLCASVD----------------DRLKVVENF----TID-S------ --GKTKILL---GNDD--Q---MIKRAGKNIRDLK-I---------------LSFNRLRVVDLFYTKN----LIALESAI NGLNPELKRRYRDNI----VKELVSEFQYKSIMQAPKIEKIVVSMGVG-DAVKNKKLLDSAVMELSQITGQKAVKTKAKK AISGFKIRQGQEIGAKVTLRGNMMYEFLYKLVNLALPRVKDFRGING-NAFDGNGNCSFGIAEQIIFSEID-----YDKI ERISGLNVTIVTT-----------------------ALNDKEGKALLAKFGMPFMSRIG-K--LPIKIADSVKVD-I--- -K-D--N-FITVEGKRGKLSQEI--NS-S--IRVKIED-NN--IIV---ER-A--FNNKQTR-AFHGLYRSLIFNMVKGV SDGFSKSLTINGIGY--RVEQQG-NS--LFFN--LGYSTQFEYVI-P-E-GINIRLD--G-NTKIAVEG-IDKCRVGQVA AEIRSLK------VPEPY---KGKGIKYDNEVIRRKVGK----------MVQMQTYLTVADNTGGKIAQCIKVLG-SKRR Y--AKVGDIIVIAVKQAIPN-S-------PVKKGDVHKAVIIRTSKEIRRKNGTYVRFDDNACVILD-ANLN-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--IKLKRPLGA-NKSKKIVG-RGQGSGL-GKTSGRGQKGQKARNSSP----- -RVGF-E-GGQTPLYRRLPR-RG--FSNVGLGDIVNYDTLFQK-GLVNIK---------ILA--NGE-L-T-K-K-VNF- EISRISKSAEELATKIGCSI-K---KQR--GRL---SGEA-QKGNKISFG----------EYGLVSL--EADFITARQIE AARVAMTRRV------KRGGKVWIRIFPDIPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEI--SG-- VPRELAESAMMLASSKLPVKTTF-VAEKKNIKRKKRIRDRI--GFGVAERPRVTIFKSNKYFYAQVIDD---I--VGRTL ASVSTI-EKEL---------SLN-KNISDVKKLGEVLAKR--LKDKN-ISKLIFDRNGYKYH--GLIAGFATALREAGID V-------------------------------------------------------------NKK-YTAKGKNLPSSPKK VRPIANNIRGKPYNEAIAILCSM---------------------------------PNKGAKLLGKVVKSAASN----AM YHNR-NLSEDMIFVKTVMVDDGRKRRSIWPRARGRADRLINRSCHIFVEVYEKTKLRVGDKVKILCGK------DR-GKV GEIASIDRKKF--KVT--VKSCNMIKKVIK----AR--TP-QEK-GKIIDKEAPMDISNVM-LFSN---------GV--I --SRVGIKF---EN--------NEKKR---YLKKSG---ENV--MGQKVHPYSLRIK--IN-RDWKSKWYF------DKK L--YSEILHEDFLIRRET--MKFLKGI---KFDISDIEIIRNNLQ-RVTVVISTPRPGSVIGVKGANLEKIGQLLTRKIN IKIKEIKK---PEFDAQIVANGIAKQLENRASYRKLLKSSLLSSISK-GIQGIKIKVSGRLGGAEIARSFEVKEGRIPL- -HTLRANIDYGFAEAYTTYGVIGVKVWLFMAVTHSVGDMLTKIRNASRVKHESVDL-KMSKINRSILDILKEEGYIKNYN IFD----K---K----GIPFIKAMLNYD---GKR-------N---PAINRIDAISTPGRKVYSSYKNMPRIKNGYGILIV SSSKGVITGKQAKDNKVGGELICSVWITKDKIRVRLFSFDVKILDQSAESIVRAVQKSKTQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGKVVSDKMSKTVVVEIVQRKMHPIYH KYLKVSRRVKAHDER--EESKLGDKVKIVESRPISKEKRWRLVEILERS------------------------------- -MARSI-KKGPFIEK-SLYQKVLASSG---KEKRV----VIKTYSRASTIIPEMVSLTISVYNGKSFIPVYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR------K- >P_Borrelia_turicatae_91E135 Concatenation of 2 sequences MGIKTYKPKTSSLRYKTTLSFDE-LSKG------N-----SP-LKSLTRGKVSRAGRDSSGRISVRR-RGGGHKRR---- YREIDFG-RR-DK-FGIPARVVSIEYDPNRSSNIALLVYR-DGDKRYIIAPKGIKVGDILESGP-N-AP-IRIGNALPLE DIPVGKAVHNIELNVGKGGQLVRGAGGYAMVLAS--KGDYVTVKLPSGEMRMIFKKCIATLGEVGNEDYINVSIGKAGKS -RWL-----GKR-P-KVRGVAMNPIDHPHGGGEGKT-S--GGRH-PVSP---WGQPTKGYKTR-KKNKYSD-K-FIIKRR ---------------------------------ML---G-LIGKKVGMTQVFQ-GNGV---------VVPVTVIEFEPNY VIGKK----TVE----R--DGY--DALIMGS-------VD--LISK----------PIRGQYN----------------- ---LENVEPKRYVIEFKG----------LKGY-----DA---GD-EIGL--D-A-FREIKYVDITGTTKGKGFQGAMKRH NFSG-GPSSHGS-KFHRH-LGGTGQA-TTPA-RTFKGTKMAGRMGGEQQTIQNLEVVFIDEEKR---------------- ----------AILVKGA-VPGVKGSFVIVKFSMERKVFS-KDGQEL-RTINLEEGVF----NI-DI-SYGSIYNAINNEL ANLRVGTASTKTRSE--------VR-GSSKKPW---------KQKGTGRAR--------VGT---KR-NP----VW---- VGGGVALGPK-P-RDYSYKLPKKVKRLAFRSVLSLCVSVE----------------DRLKIVENF----TIE-S------ --GKTKVIL--LGNDD--Q---MVKRAGKNIRDLK-I---------------LSFNRLRVVDLFYAKN----LIALESAI NGLNPALKKHYKDNI----IKELVSEFQYKSIMQAPKIEKIIVSMGVG-DAVKNKKLLDSAVYELSQITGQRAVKTKAKK AIAGFKIRQGQEIGAKVTLRGNIMYEFLYKLINLALPRVKDFRGVNG-NAFDGNGNYSFGIAEQIIFSEID-----YDKI ERISGLNVTIVTT-----------------------ALNDREGKALLSKFGMPFMSRIG-K--LPIKIVDSVKVD-I--- -K-D--N-IVTVEGKRGKLSQEL--KS-S--IKVRVED-SN--IIV---ER-S--FDDKQTR-AFHGLYRSLISNMVKGV SDGFSKSLTISGIGY--RVEQQG-TS--LFFN--LGYSTQFEYVI-P-E-GINIRLD--G-NTKIAVEG-IDKCRVGQVA AEIRGLR------VPEPY---KGKGIKYDNEVIRRKVGK----------MVQMQTYLTVADNTGGKIAECIKVLG-SKKR S--ARVGDIIVIAVKQAIPN-S-------PIKKGEVHKAVVVRTSKEIRRKNGTYVRFDDNACVILD-ANLN-PRGKRVF GPVARELR-DANFMKVVSLASEVI---M--IKLRRPLGA-NKSRKIVG-RGPGSGL-GKTSGRGQKGQKARNNSP----- -RIGF-E-GGQTPLYRRLPI-RG--FSNVGLGDIVNYNTLLQK-GLISIK---------ILA--NGE-L-T-K-K-VNF- EVSRISKSAEKLATKIGCSI-K---KQR--GRL---SGEA-QKGNEISFG----------EYGLVSL--ETYFITARQIE AARVAMTRRV------KRGGKVWIRIFPDVPYTKKPAETRMGKGK---------GGVDHWNAPVKL-GTVMFEM--AG-- VPRELAEAAMMLASSKLPVKTTF-VAEKRNIKRKKRIRDRI--GFGVADRPRVTVFKSNKYFYVQVIDD---V--AGHTL ASVSTI-EKDL---------KLN-KNIDDIRKLGEVLAKK--LKDKN-INKLIFDRNGYKYH--GLIASFATSLREAGID V-------------------------------------------------------------NRR-YTARGKNLPSSPKK VRPIADNIRGKPYSEAVAILCSM---------------------------------PNKCAKLLGKVVKSAASN----AM YHNR-NLSEDMIFIKTVMVDDGRRRRSVWPRARGRADRLVNRSCHIFVEVYEKTKLKVGDNVKILCGK------DR-GKT GEVVSIDRKNL--KVI--VKSCNMVKKVVK----AR--TP-QEK-SKIIDKEAPIDISNVM-LFSS---------GI--A --SRIGFKF---EN--------NEKKR---YLKKNG---ENV--MGQKVHPYSLRIK--IN-RDWKSKWYF------D-K K-LYSEILHEDFLIRRET--MKFLKGI---RFDISDIEIIRNNLQ-RVTVIISTPRPGSVIGVKGANLEKIGQLLTRKIN IKIKEIKK---PEFDAQIVANGIAKQLENRASYRKLLKSSLLSSISK-GVQGVKIKVSGRLGGAEIARSFEVKEGRIPL- -HTLRANIDYGFAEAQTTYGVIGVKVWLFMAVTHSVGDMLTKIRNASRVKHESVDL-KMSKINKSILDILKEEGYIKNYN IFD----K---K----GISFIKAILNYD---NKR-------N---PAINRIDAISTPGRKVYSSYKNMPRIKNGYGILIV SSSKGVITGKQAKDNKVGGELICSVWITKDKIRVRLFSFDVKILDQSAESIVRAVQKSKAQIKGPIPLPTKIKKYTVLRS PHVNKKSR-EQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQKKELIGKVVSDKMSKTIVVEIVQRKMHPIYH KYLKVSRRVKAHDER--EESKLGDKVKIIESRPISKEKRWMLVEVLEKS------------------------------- -MARSI-KKGPFIEK-SLYQKVLASSG---REKRV----VIKTYSRASTIIPEMVSLTISVYNGKSFIPVYITE-DLVGH KLGEFSPTRIFRGHA------K--SDK----KGR------K- >P_Brachyspira_hyodysenteriae_WA1,_ATCC_49526 Concatenation of 2 sequences M------------RYRTVVDFSD-ITTN------------EP-CKSLVCGKKRISGRGSNGRITMRR-RGGGHKKL---- FRFVDFR-R--DK-HDVEAKVVSIEYDPNRTARIALLHYT-DGEKRYIIWPLGLNVGDRVVSGE-N-AK-VKIGCSLPLK KIPLGTIIHNIEITPGKGGQLVRAAGGGAQITAK--SGGYCVIRLRSGEERRILENCYATIGQIGNLDHFNTTDGKAGTT -RHK-----GRR-P-KVRGVVMNPVDHPHGGGEGKS-G--QGNPHPVSP---TGVPTKGYKTR-KKHKYSD-R-LIIKRR --------------------------------MV----G-IIGKKLGMTTVFD-ETGN---------AIAVTVVEAGPCT VMQIR----DNE----K--DGY--SAIQLGY-------GA--VLKK----------PQIGQFK----------------- ---AN-LEPKKYLKEFRM--------DDASSY-----TV---GQ-ELKA--D-I-FQAGDFIDVSSLSKGRGFAGVMKRH NYDG-GPMSHGS-NFRRR-AGSIGCN-SYPA-RVWKGKGMPGHMGNTLTTIQNLKVVEIRPDDN---------------- ----------LIMIKGA-IPGAINSIVKLT--MEVVILN-ENGDSV-GNLEIVDEIF----KS-EV-NNNLLYEAIKNEL ANRRQGTHSTKTRAE--------VS-GGGKKPW---------RQKGTGRAR--------AGS---TR-SP----IW---- VGGGKTHTPK-P-RDYSYRLPKKMKRKALLSVLSLKYGSN----------------V-LKVFEDF----TFD-A------ --PKTKAFV--VKDESLGDNYNKLLLSLRNIKDLK-L---------------VNADSMSIHPLFYADE----VYFTKTAL SKLNSVLKDRYENEI----KQSLLKDMNLSSTMAIPKIEKIIINMGVT-QAVTDKKYVDSAVEELSQIAGQRAVVTRAKK SIANFKLRQGMPIGCRVTLRGERMYDFLERLIFIALPRVRDFQGIPR-RGFDGNGNYNLGIKEHTIFPEIS-----FDKT DAVKGLNITIVTT-----------------------ADNDDMARTLLERVGLPF---MA-N--KPISIPQGVEVK-I--- -D-G--H-KVIVKGKRGELTREF--FD-Y--IIFELEN-NS--LWVKPPKI-E-STDEKAKYSAQLGLVWKLISNMIEGV TNGYKKVLQLEGTGY--RSNVQG-DT--ITLQ--LGFSSDVKMKI-P-A-GIKVTVE--K-DTKIIIEG-NDKEQVGELA MNIKKKR------PVEPY---KGKGVRFDGEHVKYKESK----------MIQVPSTLNVADNTGVKKLKCIKVLG-SRRR Y--ATLGDVIICSVTDIIPT-C-------SIEKGKVVKAVIVRVKKEVRRPDGSYIRFDENAAVIVD-DKKE-PRGKRIF GPVARELR-DRGFMKIVSLAPEVIEN-T--KILRAPKGS-SKKRHRVG-RGQGSGW-GCTAGRGDKGAQSRAGYS-R--- -RAGF-E-GGQMPLHRRIPK-SG--FTNINVGDLITRETLLQM-GFLSIK---------LLS--MGE-V-K-N-A-VTI- TVDMASKKAIEKIEKSGGKV-K---HHR--GRM---KGKS-KRGSNLTFG----------DYGLMAL--EPVWLTDRQIE AARIAISRHV------KRVGKMWIKVFPDKPYTKKPAETRMGKGK---------GNVEYWVAVVKP-GKVIFEI--AG-- VPEELAQSAFRLAGFKLPIKTKF-IIKAQRERRKRSIRIKI---EGSSERPRLTVHKSLKYVSAQIIDD---S--KGITL ASASSQ-EKDL---------KSG-KNVDIAKEIGKVLATR--AKEKN-ISEVVFDRNGYIYH--GKIKSLADGAREAGLK F--------------------------------------------------------------MD-YKVKVRYLRIGRRK VARLLPFVKGEYVNHAISNLATM---------------------------------PQMSSVVLRKAIKSGIAN----A- IFQSRNINPDTLWVKTAFVDKAPTLKRIRAASRGSADPILKRLSHITIILSDKYKVKKGDTVEVIAGE------QS-GER GEVLSVDRTRG--RVL--VKNINMVKKTMP----KS--QE-NQK-GGIVEKEASIHISNVM-VVN-KA-------GK--A --TRVGRKE---V---------DGLKR---YAKKSG---EVL-----------------MN-------YY---------- ---YKTLKEEQKKIGG----KKESF-----DPAISDIQIVRFP-D-RINIFISTARAGVVIGPKGQRVETVKTTVQKMVH FSITEIRD---AELDANLAAQSVARQLEMRVAFRRAMKSVITQAMKK-GAKGIKVMCSGRLAGADIARTEQYKNGSVPL- -HTLRANIDYGTAEALTTFGIIGIKVWIYMSVHDPIADALTIIRNGCRAKKEAVTI-PFSTKMENILAILKKEGYINDFK KVE--VKD---K----NFFRIEIDLKYY----EG-------S---SVIEGIQRVSTPGLRVYTSVDTIPQVKNGFGISVI STSKGVMTDKEARKEKVGGEVLCYVWMKEQKIRVKLKAFDIELIDQSAQSIVASVKKTGARVSGPIPLPTSIRKVTVIRS PHVNIKSR-EQFEMRIYKRLIDIFDVTPQTTESLKKLALPAGVDVQLK-KRVLEGIVVSDKMDKTIVVKVESKQKHPLYG KTISKNKRYKAHDEK--NECHEGDLVRVIECRPLSKDKKFRLTKIIKKA------------------------------- -MSRSI-KKGPFVDK-NLFKKIQA------GDNKH----QIKTYSRASTIIPEMIGFTINVHNGKTFVAVYIQE-NMIGH KLGEFAPTRKFISHA------G--AAK----VGK------K- >P_candidate_division_TM7_genomosp_GTL1 Concatenation of 2 sequences MAIQAYKPTTPGRRGMTSQDFSD-ITTK------------KP-VKSLVAVKKKTAGRNNTGRITVRH-RGGGVKQF---- YRLVNHR----LA-PGTVATVEHIEYDPNRSARVARVKDQ-NGLYHYVIADKTMKQGKTIKSGS-G-IE-IETSNRMPLA DIPAGTQVYAIEIQPGKGAQMVRSAGTKAQLMAK--EGKYALVRMPSGEVRRFRVECMATIGTAGNEQHQNVKIGSAGRK -RRM-----GIR-X-TVRGVAMNAADHPHGGGDGGRHG--PGKA-PRTP---WGQLTLGYRTR-RRKYTNN---AIAKSR ----------------------------------------------------------------------MTLVQAGPCA VTQVK----TAD----K--DGY--NAVQIGY-------GE---LSN----------AVAGHVK----------------- ---AAKVTP-KVIREIRV--------NELDEI-----KV---GD-QLGV--D-L-FIVGDNVDVTGTSKGKGFAGTVKRH NFNT-SKKTHGGNGYVRK-VGSIGS--MYPQ-KIFKGKRMAGRMGHETVTVKNLSVAYIDAESN---------------- ----------LIGLKGA-VPGPRKGIVVIG----------M------ATNTLPKTVF----AV-DVPNHELLKLAYEAYL AEARTSAASTKKRGE--------VR-GGGRKPH---------KQKGTGRAR--------AGS---IR-SP----LW---- RGGGVTFGPS-GNENYKKQLNVKAKRVAVRQALTLAAQAG----------------K-IITADVS----AT--------- --GKTKLLV--VSEKS--P---ELIRATGNLQNIE-L---------------VRATYLSVFHVLNADK----IIMTPTAI TAIEPRLKALYQEKL----VTELQKELGLTNSNQVPKLEKIVVSSDIG-KHKDDKRFYEIVSNTLRKITGQQPVDRMARK SIASFKIRSGMNIGVSVTLRGARMYEFLDRLVNIALPRVRDFHGVGA-KGFDHSGNYSLGITDQSIFAELA-----FEDT QVLHGLQVTFVFR-----------------------TEKPEHTRNLLEKFGMPF-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MVQQESRLKVADNSGAKEILCIRVLG-TRRR Y--ARVGDVIVASVKDANPS-G-------NIKKKSVVKAVVVRTVDQIRRKDGSTIAFDENAAVIVN-DDKQ-PRATRVF GPVPRELR-EQGFSKIASLAPEVL-------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------K---VRK--GKN---DGVA-TRGDYLAFG----------DYGLQSL--TNERITSRQIE SARQAMTRYI------KRGGKIWIRIFPHTPVSRKPQDVKMGSGK---------GNPEFFVAKVKT-GTVMFEM--KG-- VSEEIAREAMRLAAHKLPVKTRF-I------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------VKT-VRASAKGVDQTPRK VGLIASLIRGRSVADALLILENT---------------------------------PKRAAKPVAKVVASARAN----A- VNTH-GLDSKSLRIQTIHVSPGQHLKRYRAAAMGRALPYQKRTSHINVVVSGIKKIKKNDLVMVRSGA------NK-GKT GKVLSVNNKGQ--TVL--IDGIGLVKRHIK----PS--QI-NPR-GGTKDIHVGLPVSKVTFVVDEKT-------NK--T --TRVGFIT---SK--------EGKTR---VARSLK--NKEI--MGQKVNPTSMRLQ--VN-KDWRSRWFA------GKR E--YATWLAQDIKVRKLI--EERFKS----RPTINRIEIERSA-N-LATITIHTAKAGVVIGRGGAGVSELKNQIEKIIR INIEEVKR---PELAAKLVAENIAHQLERRINFRRAVKMSALNTMNA-GAKGIRVEVAGRLNGAEMSRREKEIRGSVPL- -HTLRADIDYHLAKAQTPAGIIGVKVWIYLQSTDPVADLLTRIRNAVLVGKNEVRV-PASKLKETIARELKNAGYLADVS VED----G---K----PRGTLVVTISKD---GEN-----------SVITEIERVSKPGRRVYAGVNEIPRVKSGRGIVLV STSKGIMTGNEAIKERLGGELLCKVY------------------------------------------------------ --------------------------------------------------KKLVGVVSSDLPDKTIIVTVTRRETHPLYR KQYTVTTKYAAHDEK--NEANKGDRVEISEIPPKSKRKTFKLNRIIETG------------------------------- -MSRSL-KKGPFVDF-KLSKKVAALSP----DDRT----VLKTWARSSTITPEMIGKTIAVHNGRMHVPVFIDD-NKVGH KLGEFSPTRKFRRHG------G----K----EKK-------- >P_Candidatus_Nitrospira_defluvii Concatenation of 2 sequences MALKVYKPTTPGRRGMTAIQGEK-LTKK------------KP-EKALTGFHLRTGGRNNDGRQTIRF-RGGGHKRL---- YRQIDFR-R--DK-AGIPAKVASIEYDPNRSSRIALLHYV-DGEKRYILAPVGLSINDVVQSGV-G-AE-VRPGNALPLV NIPLGTTIHNIELKPGKGGQLIRSAGGSAQVMGR--DGAYVQIRLKSGEMRKVLSTCMATVGQVGNVDHENVVVGKAGRT -RWK-----GKR-P-HVRGVVMNPVDHPHGGGEGKS-G--QGNPHPVSP---WGTPAKGYKTR-KNKA-TD-K-FIISRR --------------------------------MTN---G-LLGKKLGMTQVY--DESV---------LAPVTVIEAGPCR VVSVK----TKE----R--DGY--EAVQLSF-------GE--VLSR----------GELGHLK----------------- ---KHQAAPSRWLREFPK----------VGDV-----TV---GQ-TVKV--D-M-FKKGDWVDVVGVSKGKGFQGVVRRH NYAG-GPETHGS-MFHRA-PGSIGAS-SYPS-RVWKNKALPGHMGDERVTVQRLKVVDARPDEN---------------- ----------LLFVRGA-VPGGVNGLLIVR-MPIVDVVD-SKKKKV-GTVDLPSEVF----GC-KP-HVPLVHEAVVMQR ACDRQGTASTLRRGE--------VS-GSGKKPW---------KQKHTGRAR--------AGS---LR-SP----VW---- RHGGTVFGPK-P-RSYAFGMPRKKYRAALQSALSAKALEG----------------N-VVVVSDL----TIN-Q------ --AKTKLLV--VGDAN--S---HLVQAGRNLSGIT-I---------------LRPEELNVYDVLRCHS----LIIPQSEL NRVKPRLRETYREQV----VPALMKEFGYGNLMQVPRLERIVLNVGMG-EAIQNVKLLESASNELGIITGQKPITTRAKK AIAGFKLRQGMPIGAKVTLRSRRMWEFLDRLISLALPRIRDFRGISP-KAFDGRGNYTLGLKEQLIFPEIE-----YDSV ASIHGMDITIVTT-----------------------ARTNDEGKALLKHLGMPFMSRIG-R--KPISVPAGVDIK-V--- -A-G--R-VVSVKGPIGKLDWTL--TD-G--LSVAVND-GQ--LVV---NR-S--GDARQIR-AMHGLVRAELSNIIQGV TKGYEKALEITGVGY--KAQLQG-RE--MSFN--VGYINPVTYTV-P-A-GIDVKVD--K-QTLISIKG-VDKRLVGQVA ANIRSIK------PPDVY---KQKGIRYAGEVLRKKAGK----------MIQNYTYMDVADNSGAKQVMCFHVLG-TRRR Y--GSLGDIVVVAVKEAIPQ-A-------GVKKGDVSRAVIVRTTKEVRRDDGSYIKFDRNACVLIN-AQGE-PVGTRIF GPVARELR-WKKFMKIISLAPEVLMK-L--HDLAPSRGA-KHKRKRIG-RGPGSGH-GKTATKGHKGLKARSGGG-K--- -RPGF-E-GGQMPLIRRVPK-YG--FTNINLKSLITPQLLMNE-GLVRIK---------ILA--QGE-L-T-K-P-LVV- QAHKFSKSAEAKIQAAGGRA-K---MQK--GRM---RGKA-YRGGAITLG----------EFGLKAL--EPGWVTSRQIE AARIAITRFV------KRGGQVWTRIFPDKPITKKPAETRMGKGK---------GNPEYWVAVVKP-GRIMYEM--SG-- VAPDVAKQALKLAAYKLPIATKF-VKNRKLARRKQRVRKSV---IGTSERPRLNVFRSRAHIYAQIIDD---L--RGHTV ASASTL-DESL-RKTV----KST-GSIEGAKAVGKLIAER--AKAAK-VSMVVFDRGGRQYH--GRVKALADASREGGLQ F-------------------------------------------------------------MAE-AKAILRFVRVTPRK ARIVIDMIRGQQVPMALAMLRHT---------------------------------PKHAARVIEKLLRSAVAN----A- EQKE-LGDSDEMWVSQAVVNCGPIYKRFRARSMGRANSIQKRTSHITIAVAAKTKIRKGDTVVVVTGR------ER-GKS GKVLSVDTVNG--KVF--VEKLNMIKRHTK----PN--QK-LRQ-GGILEREAPLAISNVM-FLCPVT-------KK--P --TRLGVKR---QE--------DGRAR---LSKKSK---EIV--MGQKTHPIGYRIG--YN-YTWSSRWYA------D-K D--YARLLHQDIKIRKMV--KAKLY-----HAGVAKVEIERSG-D-QTRVIIHTARPGIIIGRKGAEVDKLKAALEKEAY ITVKEIKK---PELDAQLVSENVATQLEKRVAFRRAMKRSVQSALRL-GAQGIKIMVAGRLGGAEIARTEWYREGRVPL- -HTLRAEVDYGFAEAHTTMGQIGVKTWIY-MITDPIADLLVRLGNAARRRQDVVKV-PVSKVKRQILNILGKEGFILGYG EMQ----E---G----GHPYFSVQLRYV---EEA-------R---PMITGMRRISKPGRRVYVGRDDVPKVRNGIGLAVI STSKGLMTDSDSRRSGLGGEVLCSVWKVDQRIRIRLRGFDYRVLDQSVVEIVETVRRSGARVVGPIPLPTRIEKFTVQRS THVDKKSR-EQFEIRTHKRLLDIMEPTPETMDSLMKLNLAAGVDVEIKLRREWYGNVVSNKMNKTVVVAVERSVIHPIYK KVLRRVTKLKAHDEG--NVCKVGDRVQLSETRPISKDKHWRVVRVMVKG------------------------------- -MPRSI-TKGPFVDD-HLMKKVEQMNQ---TKDRK----LIKTWSRRSTVVPDMIGHTFAVHNGKKFIPVFVTE-NMVGH KLGEFAPTRFFKGHG----------QA----KTE-KAVALK- >P_Leptospira_biflexa_Patoc_1_(Ames) Concatenation of 2 sequences MGIRKLKPTTQSSRYYSVLDFKE-ITEV------------VP-YKPLTANISYKAGRDNKGRIAVRR-KGGRNKRK---- FRIIDFK-R--NK-FGIPATVKTIEYDPNRSAFIALVCYA-DGEYRYILAPNGLKVGDKIESGP-A-AE-IKLGNTLPLD KIPAGTNVHNIELHIGKGGQIARTAGSFAVISAK--DGDYVSLKLPSSEIRKVRKECLATIGELSNKDHNLVIIGKAGRN -RWL-----GKR-P-KVRGVVMNPVDHPLGGGEGRT-S--GGRH-PVTP---WGKPTKGFKTR-K-TRPSD-R-FIVQRR --------------------------------MAK---G-LIGEKLGMAHIFN-NDGK---------MVTVTVLRVGPCF VSQVK----TEA----N--DGY--EAVQLAF-------GD--ALTK----------AELGHIK----------------- ---ANIATPKKTLVEFKG----------FEGV-----AV---GS-EVKL-AD-I-FALDDTVKVTGTSKGKGTQGVVKRH GFAG-GPAGHGS-RFQRH-PGSIGSN-TTPG-RVFKGLKMGGRMGSEQTTVRNLKVVKIDADAN---------------- ----------LVFVSGP-VPGRERGIVTIE--MKARKYN-KEGVFV-SEVELPAELF----AT-GI-SLGAIYDAVKAEN ANNRQGTHSTKDRSE--------VR-GGGIKPW---------AQKGTGRAR--------QGS---IR-AP----HF---- VGGGIIHGPK-P-RDYSSNLSRSVKKKAVLSILNKKAEEN----------------R-IAIIEDV----EPS-S------ --YSTKFVV--AGENQ------FLKKSTRNIENLK-Y---------------VNSKRVVCRDILYNNN----LVISESAL KELQPRLKSKYEKEI----RPTLQKSLGFQSVMRVPKLEKIVINVGMG-EAHTNPKAMEACLVEIGQITGQRPVKTFAKK SIAGFKVREGMVLGCKVTLRGHHMYEFLDRFINVALPRVRDFRGVNP-KGFDGRGNYNLSVREQIIFPEIQ-----FDKI NTIYGINITFVTN-----------------------TEVDKEAFELFQAFGMPYMSRVG-K--SIIKLPAKVEVK-A--- -D-A--E-ALTIKGPLGELKTPI--YE-G--VSANVEN-GE--LVF---TR-K--SEDQKTV-ALHGLVRSLAMNCVKGV TSGWEKNLEITGVGY--RAQKRG-KD--LVMA--LGYSHEVVFPE-P-N-GIKIEVA--D-QLKIKVSG-IDRQLVGQVA ADIRSKR------PPEPY---KGKGIKYQNEYIRRKAGK----------MIQQETILQVADNSGVKKVMCVKVLG-SKKR Y--ATLGDEIIVAVKEAQPAYGLRDGQGKKVHNKAVQRAVVVRTKKEVRRPDGTYIRFDDNAVAIID-DKGN-PKGTRIF GPVARELR-DKKYMKIISLAPEVLLG-N--KNLVPVPVGAKTSPKRVG-QGPGSGM-GKTSTRGSKGQRARASSM----- -KRGF-E-GGQMPLHKRLPK-RG--FTNVNLISLVTPAILKAK-SLIKIK---------LLG--TGE-V-T-T-A-ITI- TVDAFSASAKEKIEKAGGKV-K---RQR--GRL---KGKD-ERGSYVAFG----------EFGLKAI--SSGRITARQIE AARITINRQV------KRGGKLWIRIFPHLPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRVLFEM--AG-- VDEETARKALHLAAFKLPVETSF-VKNTKRLRRAERVRYKL---RQTSERPRLVFNKTNRYLTAQIIDD---A--KGVTL VYATTL-EKDF-PKHE----NSK-KSKSAATELGKVVADK--AKKAG-VSQVVLDRSGMVYH--GRIAAFADSAREGGLE F--------------------------------------------------------------ME-AKAVGKHLRISARK ARLVADEVRGYDYKEAIDILRFT---------------------------------NKAASSMIINLLNSAVAN----AI QMNE-SLDPNSLFVKKIYVDDGPIMKRFRPRARGRASRIRKRLSHITVVVSEKTKIKKDDEVLVISGK------EK-GKK GKVLAVDKRKD--RVY--IEGVNKRKRFVR----PT--QE-NPG-GGAIEIEFPIHISNVM-FHDAKAENKAKPKKKIKA --VRLGFAK----K--------DGSVR---VTRPEG---KEV--MGQKVNPIGLRIG--IT-RNWDSVWFS------K-Q D--YIKNLHEDIKIRRFL--QKKFK-----NASVVKIIIERFP-E-KINVNLHTSKPGMVIGQKGQNIEAVKQELKKFIG MNIIEVKK---PEIIAQAIAETVALQIEQRMPFRRVMKAELRRAMRG-GVEGVKIQISGRLNGADMARTEKYMEGRVPL- -HTLRAKIDFGFKEALTTFGQIGVKVWTYMSLSDPIADMLTRIRNAQQAKHELCVI-PGSKIKKSILDLLKEEGFVDDVQ TVK----N---G----SFDDFQVKLKYD---TEK-------K---PVIRMIERVSTPGRRVYIQSGEIRPFRNNIGTLIL STSKGVMTGKRARKLRVGGEVLCKVFMAGQRIRVKLKAFDHRLIDQSTFEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKAR-EQFEMRTHKRLIDILNTNEDTVEALMKLQLPAGVSVDIKSSLTIQGVVVSDAMDKTVVIEIITRKVHPRFK KIMTRTSRVKIHDEK--NECQVGDRVIAVETRPLSKQKHHKLVKVIEKA------------------------------- -MARSL-KKGPFIDD-HLMKKITKLNS---EGKKT----PFKSWSRRSTIYPDMIGHTVMIHNGKAFVPVYVNE-NMIGH KLGEFAPTRTFKGHG------G---DK----KVA------KK >P_Leptospira_biflexa_Patoc_1_(Paris) Concatenation of 2 sequences MGIRKLKPTTQSSRYYSVLDFKE-ITEV------------VP-YKPLTANISYKAGRDNKGRIAVRR-KGGRNKRK---- FRIIDFK-R--NK-FGIPATVKTIEYDPNRSAFIALVCYA-DGEYRYILAPNGLKVGDKIESGP-A-AE-IKLGNTLPLD KIPAGTNVHNIELHIGKGGQIARTAGSFAVISAK--DGDYVSLKLPSSEIRKVRKECLATIGELSNKDHNLVIIGKAGRN -RWL-----GKR-P-KVRGVVMNPVDHPLGGGEGRT-S--GGRH-PVTP---WGKPTKGFKTR-K-TRPSD-R-FIVQRR --------------------------------MAK---G-LIGEKLGMAHIFN-NDGK---------MVTVTVLRVGPCF VSQVK----TEA----N--DGY--EAVQLAF-------GD--ALTK----------AELGHIK----------------- ---ANIATPKKTLVEFKG----------FEGV-----AV---GS-EVKL-AD-I-FALDDTVKVTGTSKGKGTQGVVKRH GFAG-GPAGHGS-RFQRH-PGSIGSN-TTPG-RVFKGLKMGGRMGSEQTTVRNLKVVKIDADAN---------------- ----------LVFVSGP-VPGRERGIVTIE--MKARKYN-KEGVFV-SEVELPAELF----AT-GI-SLGAIYDAVKAEN ANNRQGTHSTKDRSE--------VR-GGGIKPW---------AQKGTGRAR--------QGS---IR-AP----HF---- VGGGIIHGPK-P-RDYSSNLSRSVKKKAVLSILNKKAEEN----------------R-IAIIEDV----EPS-S------ --YSTKFVV--AGENQ------FLKKSTRNIENLK-Y---------------VNSKRVVCRDILYNNN----LVISESAL KELQPRLKSKYEKEI----RPTLQKSLGFQSVMRVPKLEKIVINVGMG-EAHTNPKAMEACLVEIGQITGQRPVKTFAKK SIAGFKVREGMVLGCKVTLRGHHMYEFLDRFINVALPRVRDFRGVNP-KGFDGRGNYNLSVREQIIFPEIQ-----FDKI NTIYGINITFVTN-----------------------TEVDKEAFELFQAFGMPYMSRVG-K--SIIKLPAKVEVK-A--- -D-A---EALTIKGPLGELKTPI--YE-G--VSANVEN-GE--LVF---TR-K--SEDQKTV-ALHGLVRSLAMNCVKGV TSGWEKNLEITGVGY--RAQKRG-KD--LVMA--LGYSHEVVFPE-P-N-GIKIEVA--D-QLKIKVSG-IDRQLVGQVA ADIRSKR------PPEPY---KGKGIKYQNEYIRRKAGK----------MIQQETILQVADNSGVKKVMCVKVLG-SKKR Y--ATLGDEIIVAVKEAQPAYGLRDGQGKKVHNKAVQRAVVVRTKKEVRRPDGTYIRFDDNAVAIID-DKGN-PKGTRIF GPVARELR-DKKYMKIISLAPEVLLG-N--KNLVPVPVGAKTSPKRVG-QGPGSGM-GKTSTRGSKGQRARASSM----- -KRGF-E-GGQMPLHKRLPK-RG--FTNVNLISLVTPAILKAK-SLIKIK---------LLG--TGE-V-T-T-A-ITI- TVDAFSASAKEKIEKAGGKV-K---RQR--GRL---KGKD-ERGSYVAFG----------EFGLKAI--SSGRITARQIE AARITINRQV------KRGGKLWIRIFPHLPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRVLFEM--AG-- VDEETARKALHLAAFKLPVETSF-VKNTKRLRRAERVRYKL---RQTSERPRLVFNKTNRYLTAQIIDD---A--KGVTL VYATTL-EKDF-PKHE----NSK-KSKSAATELGKVVADK--AKKAG-VSQVVLDRSGMVYH--GRIAAFADSAREGGLE F-------------------------------------------------------------MME-AKAVGKHLRISARK ARLVADEVRGYDYKEAIDILRFT---------------------------------NKAASSMIINLLNSAVAN----AI QMNE-SLDPNSLFVKKIYVDDGPIMKRFRPRARGRASRIRKRLSHITVVVSEKTKIKKDDEVLVISGK------EK-GKK GKVLAVDKRKD--RVY--IEGVNKRKRFVR----PT--QE-NPG-GGAIEIEFPIHISNVM-FHDAKAENKAKPKKKIKA --VRLGFAK----K--------DGSVR---VTRPEG---KEV--MGQKVNPIGLRIG--IT-RNWDSVWFS------K-Q D--YIKNLHEDIKIRRFL--QKKFK-----NASVVKIIIERFP-E-KINVNLHTSKPGMVIGQKGQNIEAVKQELKKFIG MNIIEVKK---PEIIAQAIAETVALQIEQRMPFRRVMKAELRRAMRG-GVEGVKIQISGRLNGADMARTEKYMEGRVPL- -HTLRAKIDFGFKEALTTFGQIGVKVWTYMSLSDPIADMLTRIRNAQQAKHELCVI-PGSKIKKSILDLLKEEGFVDDVQ TVK----N---G----SFDDFQVKLKYD---TEK-------K---PVIRMIERVSTPGRRVYIQSGEIRPFRNNIGTLIL STSKGVMTGKRARKLRVGGEVLCKVFMAGQRIRVKLKAFDHRLIDQSTFEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKAR-EQFEMRTHKRLIDILNTNEDTVEALMKLQLPAGVSVDIKSSLTIQGVVVSDAMDKTVVIEIITRKVHPRFK KIMTRTSRVKIHDEK--NECQVGDRVIAVETRPLSKQKHHKLVKVIEKA------------------------------- -MARSL-KKGPFIDD-HLMKKITKLNS---EGKKT----PFKSWSRRSTIYPDMIGHTVMIHNGKAFVPVYVNE-NMIGH KLGEFAPTRTFKGHG------G---DK----KVA------KK >P_Leptospira_borgpetersenii_sv_Hardjo-bovis_JB197 Concatenation of 2 sequences MGIKKFKPVTSASRYKSVLDFKE-ITET------------EP-YKPLTLTLSYKAGRGDGGKISVRH-KGGRVKRK---- YRIIDFK-R--RK-TNVSAVVKTLEYDPNRSAFISLICYK-DGEYAYILAPDGIKVGDTVQSGA-G-SE-IKIGNAMPIG KIPPGTNVHNVELQIGRGGQIARTAGSFGTIAGR--DGEYILLKLPSTEVRKVHENCYATIGICSNKDHNLVSIGKAGRS -RWL-----GKR-P-TVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGQPTKGYKTR-RSARPSD-K-FIVQKR --------------------------------MAK---G-LIGKKVGMSQIFD-EQGN---------IIPVTVLEVGPCA VSQVK----SVE----N--DGY--EAIQLAF-------QD--TISK----------AEKNHLK----------------- ---AS-LGPKKVLREFRS---------FGDSP-----AT---GS-VLKV-QD-I-FAVSDVVKVTGVSKGRGFQGVVKRH GHAG-GPGGHGS-RFHRH-PGSMGAN-STPS-RVFKGVKLPGRTGSQQTTVRNLKVVRINEEKN---------------- ----------LVFVSGA-VPGTTNTVITIE--MKAQKYS-KEGKLI-SEIELPSALF----ES-KL-SVASIYEAIKAEN ANLRSGNHATKTRSE--------VR-GGGKKPW---------SQKGTGHAR--------QGS---TR-AP----HW---- VGGGTVHGPQ-K-RDYSYKVSSKLKHKAVLSILNKKAQAS----------------A-VKVIEDL----DPK-E------ --YSTKFLV--QGESD------FVKKSVRNIPTVK-Y---------------INSKRISCRDILYNRN----LVITEAAL NEMLARLRTKYKKEI----VPELNKKFKFESIMQVPRLEKIVLNVGMG-EAHTNPKALEAAVEELALITGQRPVKTKAKK SIAGFKIREGMSLGCMVTLRGDYMYEFLDRLVNVALPRVRDFKGVND-KGFDGRGNYNMSIKEQIIFPEIK-----VDKI NTLYGINMTFVTN-----------------------SKSNEEALSLLAAFGMPYMSRIG-K--AEIKLPDKVEVK----- -Q-E--NANIKVKGPLGELSTPI--FE-G--LSVKNEN-GI--VKL---ER-S--NEDQKVV-ALHGLTRALLMNCVKGV SQGWEKNLEINGVGY--RAQKRG-ED--LVMS--LGYSHEVVYKA-P-K-GIKIDVQ--E-QLKIKVTG-IDKQLVGQVA ADIRSKR------PPEPY---KGKGIKYAEEFIKKKAGK----------MIQQETWLQVADNSGIKKVMCIKVLG-SKKR Y--ASVGDEIIVAVKDAQPAFGLKDSTGKKVHNKAVQRAVVVRTTKEIRRPDGSYIRFDDNACAIID-DKGN-PKGTRIF GPVARELR-DKKYAKIISLAPEVLDT-T--SNLVPVPKGAKKEKKRVG-RGPGSKV-GKTAGRGSKGQYARNT---V--- -RRGF-E-GGQMPIHRRLPK-RG--FTAVNLRDIIDAKIMVQS-KILDFK---------ILG--TGE-I-K-K-A-IHV- IADGFSQSAKEKIEKAGGSI-K---RQR--GRL---KGTD-ERGSSVSFG----------EFGLKAV--TSGRLTARQIE AARITINRQV------KRGGKLWIRIFPHTPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRILFEM--SG-- IDEETAEKALSLASYKLPIHTEF-VKSVSKIRRAERSRFKL---KKSGSRPRLVFNKSNKYLSCQIVDD---I--QGVTL AYATTS-EKTF-SSEG----KSK-KDVGAAKVLGKLIAER--GSQKG-VKQVMLDRSGMIFH--GRIAAFAEGAREAGLE F--------------------------------------------------------------ME-AKAVARFVRMSPRK VRLVADEIRGYAVGEALDILKFT---------------------------------NKRAIEPLTKVILSASAN----AS VLND-KVDSNQLFIKKIYVDEGPIMKRFRPRARGRAARIRKRLSHITVVLSDKFRFKKNDEVICIAGK------EK-GKK GKVLSIDKKRD--RVI--VEGLNKRKRFMR----PT--QE-NPQ-GGVIEVEAAIHISNVM-FYDSKK-------KA--G --VRIGFET----I--------KGKVR---VSRPDK---KEL--MGQKVNPIGLRIG--IT-RGWDSIWFS------Q-S D--YKKNLHEDIKIRKFI--QSRFS-----NAGVVKVVIERFP-E-KINVNLHTAKPGIVIGQKGSNIEAVKKILKTMVN LNIIEVKK---PETVAQCIAESIALQIEQRQPFRRVMKQELRRAMRG-GVEGIKILISGRLNGADMARRENYKEGRIPL- -HTLRAKIDLGFKEAKTTFGQIGVKVWTYMSMSDPIGDMLTRIRNAGRAKHDTCLV-PGSKIKKSILDLMKEEGFIRDYE SVK---VN---E----TFEDYKVFLKYD---QTK-------R---PIIRELIRVSTPGRRVYIKSTEIRPYKNNIGTLIV STSKGIMTGKNARKLKLGGEVILKMSMAGQKIRVKLKAFDHRLIDQSTYEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKSR-EQFELKTHKRLIDILDTNEDTVEALMKLQLPAGVSVDIKSSLLYEGRVVSNSMNKTVVIVVETRKTHPKFK KIVRRSIKIKVHDEK--NECTIGDKILAIETRPLSREKRHRLYRIVEKA------------------------------- -MARSV-KKGPFIDD-HLMKKITKLNS---ENQKK----PFKTWSRRSTIFPDMVGHTVMVHNGKQFTPVYINE-NMIGH KLGEFSPTRTFRGHV------A--GDK----KAA------KK >P_Leptospira_borgpetersenii_sv_Hardjo-bovis_L550 Concatenation of 2 sequences MGIKKFKPVTSASRYKSVLDFKE-ITET------------EP-YKPLTLTLSYKAGRGDGGKISVRH-KGGRVKRK---- YRIIDFK-R--RK-TNVSAVVKTLEYDPNRSAFISLICYK-DGEYAYILAPDGIKVGDTVQSGA-G-SE-IKIGNAMPIG KIPPGTNVHNVELQIGRGGQIARTAGSFGTIAGR--DGEYILLKLPSTEVRKVHENCYATIGICSNKDHNLVSIGKAGRS -RWL-----GKR-P-TVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGQPTKGYKTR-RSARPSD-K-FIVQKR --------------------------------MAK---G-LIGKKVGMSQIFD-EQGN---------IIPVTVLEVGPCA VSQVK----SVE----N--DGY--EAIQLAF-------QD--TISK----------AEKNHLK----------------- ---AS-LGPKKVLREFRS---------FGDSP-----AT---GS-VLKV-QD-I-FAVSDVVKVTGVSKGRGFQGVVKRH GHAG-GPGGHGS-RFHRH-PGSMGAN-STPS-RVFKGVKLPGRTGSQQTTVRNLKVVRINEEKN---------------- ----------LVFVSGA-VPGTTNTVITIE--MKAQKYS-KEGKLI-SEIELPSALF----ES-KL-SVASIYEAIKAEN ANLRSGNHATKTRSE--------VR-GGGKKPW---------SQKGTGHAR--------QGS---TR-AP----HW---- VGGGTVHGPQ-K-RDYSYKVSSKLKHKAVLSILNKKAQAS----------------A-VKVIEDL----DPK-E------ --YSTKFLV--QGESD------FVKKSVRNIPTVK-Y---------------INSKRISCRDILYNRN----LVITEAAL NEMLARLRTKYKKEI----VPELNKKFKFESIMQVPRLEKIVLNVGMG-EAHTNPKALEAAVEELALITGQRPVKTKAKK SIAGFKIREGMSLGCMVTLRGDYMYEFLDRLVNVALPRVRDFKGVND-KGFDGRGNYNMSIKEQIIFPEIK-----VDKI NTLYGINMTFVTN-----------------------SKSNEEALSLLAAFGMPYMSRIG-K--AEIKLPDKVEVK----- -Q-E-NA-NIKVKGPLGELSTPI--FE-G--LSVKNEN-GI--VKL---ER-S--NEDQKVV-ALHGLTRALLMNCVKGV SQGWEKNLEINGVGY--RAQKRG-ED--LVMS--LGYSHEVVYKA-P-K-GIKIDVQ--E-QLKIKVTG-IDKQLVGQVA ADIRSKR------PPEPY---KGKGIKYAEEFIKKKAGK----------MIQQETWLQVADNSGIKKVMCIKVLG-SKKR Y--ASVGDEIIVAVKDAQPAFGLKDSTGKKVHNKAVQRAVVVRTTKEIRRPDGSYIRFDDNACAIID-DKGN-PKGTRIF GPVARELR-DKKYAKIISLAPEVLDT-T--SNLVPVPKGAKKEKKRVG-RGPGSKV-GKTAGRGSKGQYARNT---V--- -RRGF-E-GGQMPIHRRLPK-RG--FTAVNLRDIIDAKIMVQS-KILDFK---------ILG--TGE-I-K-K-A-IHV- IADGFSQSAKEKIEKAGGSI-K---RQR--GRL---KGTD-ERGSSVSFG----------EFGLKAV--TSGRLTARQIE AARITINRQV------KRGGKLWIRIFPHTPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRILFEM--SG-- IDEETAEKALSLASYKLPIHTEF-VKSVSKIRRAERSRFKL---KKSGSRPRLVFNKSNKYLSCQIVDD---I--QGVTL AYATTS-EKTF-SSEG----KSK-KDVGAAKVLGKLIAER--GSQKG-VKQVMLDRSGMIFH--GRIAAFAEGAREAGLE F--------------------------------------------------------------ME-AKAVARFVRMSPRK VRLVADEIRGYAVGEALDILKFT---------------------------------NKRAIEPLTKVILSASAN----AS VLND-KVDSNQLFIKKIYVDEGPIMKRFRPRARGRAARIRKRLSHITVVLSDKFRFKKNDEVICIAGK------EK-GKK GKVLSIDKKRD--RVI--VEGLNKRKRFMR----PT--QE-NPQ-GGVIEVEAAIHISNVM-FYDSKK-------KA--G --VRIGFET----I--------KGKVR---VSRPDK---KEL--MGQKVNPIGLRIG--IT-RGWDSIWFS------Q-S D--YKKNLHEDIKIRKFI--QSRFS-----NAGVVKVVIERFP-E-KINVNLHTAKPGIVIGQKGSNIEAVKKILKTMVN LNIIEVKK---PETVAQCIAESIALQIEQRQPFRRVMKQELRRAMRG-GVEGIKILISGRLNGADMARRENYKEGRIPL- -HTLRAKIDLGFKEAKTTFGQIGVKVWTYMSMSDPIGDMLTRIRNAGRAKHDTCLV-PGSKIKKSILDLMKEEGFIRDYE SVK---VN---E----TFEDYKVFLKYD---QTK-------R---PIIRELIRVSTPGRRVYIKSTEIRPYKNNIGTLIV STSKGIMTGKNARKLKLGGEVILKMSMAGQKIRVKLKAFDHRLIDQSTYEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKSR-EQFELKTHKRLIDILDTNEDTVEALMKLQLPAGVSVDIKSSLLYEGRVVSNSMNKTVVIVVETRKTHPKFK KIVRRSIKIKVHDEK--NECTIGDKILAIETRPLSREKRHRLYRIVEKA------------------------------- -MARSV-KKGPFIDD-HLMKKITKLNS---ENQKK----PFKTWSRRSTIFPDMVGHTVMVHNGKQFTPVYINE-NMIGH KLGEFSPTRTFRGHV------A--GDK----KAA------KK >P_Leptospira_borgpetersenii_sv_Hardjo-bovis_L550_2 Concatenation of 2 sequences MGIKKFKPVTSASRYKSVLDFKE-ITET------------EP-YKPLTLTLSYKAGRGDGGKISVRH-KGGRVKRK---- YRIIDFK-R--RK-TNVSAVVKTLEYDPNRSAFISLICYK-DGEYAYILAPDGIKVGDTVQSGA-G-SE-IKIGNAMPIG KIPPGTNVHNVELQIGRGGQIARTAGSFGTIAGR--DGEYILLKLPSTEVRKVHENCYATIGICSNKDHNLVSIGKAGRS -RWL-----GKR-P-TVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGQPTKGYKTR-RSARPSD-K-FIVQKR --------------------------------MAK---G-LIGKKVGMSQIFD-EQGN---------IIPVTVLEVGPCA VSQVK----SVE----N--DGY--EAIQLAF-------QD--TISK----------AEKNHLK----------------- ---AS-LGPKKVLREFRS---------FGDSP-----AT---GS-VLKV-QD-I-FAVSDVVKVTGVSKGRGFQGVVKRH GHAG-GPGGHGS-RFHRH-PGSMGAN-STPS-RVFKGVKLPGRTGSQQTTVRNLKVVRINEEKN---------------- ----------LVFVSGA-VPGTTNTVITIE--MKAQKYS-KEGKLI-SEIELPSALF----ES-KL-SVASIYEAIKAEN ANLRSGNHATKTRSE--------VR-GGGKKPW---------SQKGTGHAR--------QGS---TR-AP----HW---- VGGGTVHGPQ-K-RDYSYKVSSKLKHKAVLSILNKKAQAS----------------A-VKVIEDL----DPK-E------ --YSTKFLV--QGESD------FVKKSVRNIPTVK-Y---------------INSKRISCRDILYNRN----LVITEAAL NEMLARLRTKYKKEI----VPELNKKFKFESIMQVPRLEKIVLNVGMG-EAHTNPKALEAAVEELALITGQRPVKTKAKK SIAGFKIREGMSLGCMVTLRGDYMYEFLDRLVNVALPRVRDFKGVND-KGFDGRGNYNMSIKEQIIFPEIK-----VDKI NTLYGINMTFVTN-----------------------SKSNEEALSLLAAFGMPYMSRIG-K--AEIKLPDKVEVK-Q--- -E-N--A-NIKVKGPLGELSTPI--FE-G--LSVKNEN-GI--VKL---ER-S--NEDQKVV-ALHGLTRALLMNCVKGV SQGWEKNLEINGVGY--RAQKRG-ED--LVMS--LGYSHEVVYKA-P-K-GIKIDVQ--E-QLKIKVTG-IDKQLVGQVA ADIRSKR------PPEPY---KGKGIKYAEEFIKKKAGK----------MIQQETWLQVADNSGIKKVMCIKVLG-SKKR Y--ASVGDEIIVAVKDAQPAFGLKDSTGKKVHNKAVQRAVVVRTTKEIRRPDGSYIRFDDNACAIID-DKGN-PKGTRIF GPVARELR-DKKYAKIISLAPEVLDT-T--SNLVPVPKGAKKEKKRVG-RGPGSKV-GKTAGRGSKGQYARNT---V--- -RRGF-E-GGQMPIHRRLPK-RG--FTAVNLRDIIDAKIMVQS-KILDFK---------ILG--TGE-I-K-K-A-IHV- IADGFSQSAKEKIEKAGGSI-K---RQR--GRL---KGTD-ERGSSVSFG----------EFGLKAV--TSGRLTARQIE AARITINRQV------KRGGKLWIRIFPHTPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRILFEM--SG-- IDEETAEKALSLASYKLPIHTEF-VKSVSKIRRAERSRFKL---KKSGSRPRLVFNKSNKYLSCQIVDD---I--QGVTL AYATTS-EKTF-SSEG----KSK-KDVGAAKVLGKLIAER--GSQKG-VKQVMLDRSGMIFH--GRIAAFAEGAREAGLE F--------------------------------------------------------------ME-AKAVARFVRMSPRK VRLVADEIRGYAVGEALDILKFT---------------------------------NKRAIEPLTKVILSASAN----AS VLND-KVDSNQLFIKKIYVDEGPIMKRFRPRARGRAARIRKRLSHITVVLSDKFRFKKNDEVICIAGK------EK-GKK GKVLSIDKKRD--RVI--VEGLNKRKRFMR----PT--QE-NPQ-GGVIEVEAAIHISNVM-FYDSKK-------KA--G --VRIGFET----I--------KGKVR---VSRPDK---KEL--MGQKVNPIGLRIG--IT-RGWDSIWFS------Q-S D--YKKNLHEDIKIRKFI--QSRFS-----NAGVVKVVIERFP-E-KINVNLHTAKPGIVIGQKGSNIEAVKKILKTMVN LNIIEVKK---PETVAQCIAESIALQIEQRQPFRRVMKQELRRAMRG-GVEGIKILISGRLNGADMARRENYKEGRIPL- -HTLRAKIDLGFKEAKTTFGQIGVKVWTYMSMSDPIGDMLTRIRNAGRAKHDTCLV-PGSKIKKSILDLMKEEGFIRDYE SVK---VN---E----TFEDYKVFLKYD---QTK-------R---PIIRELIRVSTPGRRVYIKSTEIRPYKNNIGTLIV STSKGIMTGKNARKLKLGGEVILKMSMAGQKIRVKLKAFDHRLIDQSTYEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKSR-EQFELKTHKRLIDILDTNEDTVEALMKLQLPAGVSVDIKSSLLYEGRVVSNSMNKTVVIVVETRKTHPKFK KIVRRSIKIKVHDEK--NECTIGDKILAIETRPLSREKRHRLYRIVEKA------------------------------- -MARSV-KKGPFIDD-HLMKKITKLNS---ENQKK----PFKTWSRRSTIFPDMVGHTVMVHNGKQFTPVYINE-NMIGH KLGEFSPTRTFRGHV------A--GDK----KAA------KK >P_Leptospira_interrogans_sv_Copenhageni_Fiocruz_L1-130 Concatenation of 2 sequences MGIKKFKPVTSASRYKSVLDFAE-ITET------------EP-YKPLTLTLNYKAGRGDGGKIAVRH-KGGRVKRK---- YRIIDFK-R--RK-ANIPAVVKSLEYDPNRSAFISLICYK-DGEYSYILAPDGIKVGDTVQSGA-G-SE-IKIGNAMPIG KIPPGTNVHNVELQIGKGGQIARTAGSFGTIAGR--DGEYILLKLPSSEVRKVHENCYATIGICSNKDHNLVSIGKAGRS -RWL-----GKR-P-SVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGQPTKGYKTR-RSTRPSD-K-FIIQKR --------------------------------MAK---G-LIGKKVGMSQIFD-EQGN---------IIPVTVLEVGPCA VSQVK----SVE----N--DGY--EAIQLAF-------QD--ITSK----------AEKNHLK----------------- ---AG-LGPKKVLKEFRS---------FGDSP-----TA---GS-VLKI-QD-V-FAVSDVVKVTGVSKGRGYQGVVKRH GHAG-GPGAHGS-RFHRH-PGSMGAN-STPS-RVFKGVKLPGRTGSQKTTVRNLKVVRINEEKN---------------- ----------LLFVSGA-VPGTANTVITIE--MKAQKYS-KEGKLI-SEIELPSALF----ES-KL-SVASIYEAIKAEN ANLRSGNHATKTRSM--------VS-GGGKKPW---------SQKGTGRAR--------QGS---TR-AP----HW---- VGGGTVHGPQ-K-RDYSYKVSSKLKHRAVLSILGKKAQAS----------------A-VKVVEDL----DPK-E------ --YNTKLLV--QGEND------FLKKSVRNIPTVK-Y---------------INSKRISCRDILYNRN----LVITEAAL KEMLARLRTKYKKEI----VPELNKKFKFSSIMQVPRLEKIVLNVGMG-EAHTNPKALEAAVEELALITGQRPVKTKAKK SIAGFKIREGMSLGCMVTLRGDYMYEFLDRLVNVALPRVRDFKGVSE-KGFDGRGNYNMSIKEQIIFPEIK-----VDKI NTLYGINMTFVTN-----------------------SKSNEEAYSLLAAFGMPYMSRIG-K--AEIKLPDKVEVK----- -Q-E--NANIKVKGPLGELFTPI--FE-G--ISVKTEN-GI--VKL---ER-S--NEDQKVV-ALHGLTRALLMNCVKGV SQGWEKNLEITGVGY--RAQKRG-ED--LVMS--LGFSHEVVYKA-P-K-GIKIDVQ--E-QLKIKVSG-IDKQLVGQVA ADIRSKR------PPEPY---KGKGIKYAEEFIKKKAGK-----------------------------MCIKVLG-SKKR Y--ASVGDEIIVAVKDAQPAFGLKDSTGKKVHNKAVQRAVVVRTTKEIRRPDGSYIRFDDNACAIID-DKGN-PKGTRIF GPVARELR-DKKYAKIISLAPEVLDT-S--SNLIPVPKGATKEKKRVG-RGPGSKV-GKTAGRGSKGQYARNT---V--- -RRGF-E-GGQMPIHRRLPK-RG--FTSVNLRDIIDAKIMVQS-KILDFK---------ILG--TGE-I-K-K-A-IHV- IADGFSQSAKEKIEKAGGSI-K---RQR--GRL---KGTD-ERGSSVSFG----------EFGLKAV--TSGRLTARQIE AARITINRQV------KRGGKLWIRIFPHTPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRILFEM--SG-- IDEETAKKALSLASYKLPIHTEF-VKSISKTKRAERSRFKL---KKLGSRPRLVFIKSNQYLSCQIIDD---I--QGVTL AYATTS-EKTF-TGEG----KSK-KDKGAAKVLGKLIAER--GSQKG-VKQVMLDRSGMIFH--GRIAAFAEGAREAGLE F--------------------------------------------------------------ME-AKAVSRFVRMSPRK VRLVADEIRGYAVNEALDILKFT---------------------------------NKRAIEPLTKVILSASAN----AS VLNN-KVDFNQLFIKKIYVDEGPIMKRFRPRARGRAARIRKRLSHITVVLSDKFRIKKNDEVICITGK------HK-GKR GKVLSIDKKRD--RVI--VEGLNKRKRFMR----PT--QE-NPQ-GGVIEVEAPIHISNVM-FYDPKK-------KKKAG --VRVGFET----V--------KGKVR---VSRPDK---KEL--MGQKVNPIGLRIG--IT-RGWDSIWFS------Q-S D--YKKNLHEDIKIRKFV--QNRFN-----NAGVVKVVIERFP-E-KINVNLHTAKPGIVIGQKGANIEAVKKILKTMVN LNIIEVKK---PETVAQCIAESIALQIEQRQPFRRVMKQELRRAMRG-GVEGIKILISGRLNGADMARRENYKEGRIPL- -HTLRAKIDLGFKEAKTTFGQIGVKVWTYMSMSDPIGDMLTRIRNAGRAKHETCLV-PGSKIKKSILDLMKEEGFIKDYE SVK---VN---E----TFEDYKVFLKYD---HTK-------R---PIIRELVRVSTPGRRVYIKSAEIRPYKNNIGTLIV STSKGIMTGKNARKLKLGGEVILKMSMAGQKIRVKLKAFDHRLIDQSTYEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKSR-EQFELKTHKRLIDILDTNEDTVEALMKLQLPAGVSVDIKSSLLYEGRVVSNSMNKTVVILVETRKTHPKFK KIVRRSVRLKVHDEK--NECVVGDKILAIETRPLSKEKRHRLYKIVEKA------------------------------- -MARSV-KKGPFIDD-HLMKKITKLNS---ENQKK----PFKTWSRRSTIFPDMVGHTVMVHNGKQFTPVYINE-NMIGH KLGEFSPTRTFRAHV------A--GDK----KAA------KK >P_Leptospira_interrogans_sv_Lai_56601 Concatenation of 2 sequences MGIKKFKPVTSASRYKSVLDFAE-ITET------------EP-YKPLTLTLNYKAGRGDGGKIAVRH-KGGRVKRK---- YRIIDFK-R--RK-ANIPAVVKSLEYDPNRSAFISLICYK-DGEYSYILAPDGIKVGDTVQSGA-G-SE-IKIGNAMPIG KIPPGTNVHNVELQIGKGGQIARTAGSFGTIAGR--DGEYILLKLPSSEVRKVHENCYATIGICSNKDHNLVSIGKAGRS -RWL-----GKR-P-SVRGVVMNPVDHPHGGGEGRT-S--GGRH-PVSP---WGQPTKGYKTR-RSTRPSD-K-FIIQKR --------------------------------MAK---G-LIGKKVGMSQIFD-EQGN---------IIPVTVLEVGPCA VSQVK----SVE----N--DGY--EAIQLAF-------QD--ITSK----------AEKNHLK----------------- ---AG-LGPKKVLKEFRS---------FGDSP-----TA---GS-VLKI-QD-V-FAVSDVVKVTGVSKGRGYQGVVKRH GHAG-GPGAHGS-RFHRH-PGSMGAN-STPS-RVFKGVKLPGRTGSQKTTVRNLKVVRINEEKN---------------- ----------LLFVSGA-VPGTANTVITIE--MKAQKYS-KEGKLI-SEIELPSALF----ES-KL-SVASIYEAIKAEN ANLRSGNHATKTRSM--------VS-GGGKKPW---------SQKGTGRAR--------QGS---TR-AP----HW---- VGGGTVHGPQ-K-RDYSYKVSSKLKHRAVLSILGKKAQAS----------------A-VKVVEDL----DPK-E------ --YNTKLLV--QGEND------FLKKSVRNIPTVK-Y---------------INSKRISCRDILYNRN----LVITEAAL KEMLARLRTKYKKEI----VPELNKKFKFSSIMQVPRLEKIVLNVGMG-EAHTNPKALEAAVEELALITGQRPVKTKAKK SIAGFKIREGMSLGCMVTLRGDYMYEFLDRLVNVALPRVRDFKGVSE-KGFDGRGNYNMSIKEQIIFPEIK-----VDKI NTLYGINMTFVTN-----------------------SKSNEEAYSLLAAFGMPYMSRIG-K--AEIKLPDKVEVK----- -Q-E--NANIKVKGPLGELFTPI--FE-G--ISVKTEN-GI--VKL---ER-S--NEDQKVV-ALHGLTRALLMNCVKGV SQGWEKNLEITGVGY--RAQKRG-ED--LVMS--LGFSHEVVYKA-P-K-GIKIDVQ--E-QLKIKVSG-IDKQLVGQVA ADIRSKR------PPEPY---KGKGIKYAEEFIKKKAGK----------MIQQETLLQVADNSGIKKVMCIKVLG-SKKR Y--ASVGDEIIVAVKDAQPAFGLKDSTGKKVHNKAVQRAVVVRTTKEIRRPDGSYIRFDDNACAIID-DKGN-PKGTRIF GPVARELR-DKKYAKIISLAPEVLDT-S--SNLIPVPKGATKEKKRVG-RGPGSKV-GKTAGRGSKGQYARNT---V--- -RRGF-E-GGQMPIHRRLPK-RG--FTSVNLRDIIDAKIMVQS-KILDFK---------ILG--TGE-I-K-K-A-IHV- IADGFSQSAKEKIEKAGGSI-K---RQR--GRL---KGTD-ERGSSVSFG----------EFGLKAV--TSGRLTARQIE AARITINRQV------KRGGKLWIRIFPHTPITKKPAETRMGKGK---------GNPEFWIAEIRP-GRILFEM--SG-- IDEETAKKALSLASYKLPIHTEF-VKSISKTKRAERSRFKL---KKLGSRPRLVFIKSNQYLSCQIIDD---I--QGVTL AYATTS-EKTF-TGEG----KSK-KDKGAAKVLGKLIAER--GSQKG-VKQVMLDRSGMIFH--GRIAAFAEGAREAGLE F--------------------------------------------------------------ME-AKAVSRFVRMSPRK VRLVADEIRGYAVNEALDILKFT---------------------------------NKRAIEPLTKVILSASAN----AS VLNN-KVDFNQLFIKKIYVDEGPIMKRFRPRARGRAARIRKRLSHITVVLSDKFRIKKNDEVICITGK------HK-GKR GKVLSIDKKRD--RVI--VEGLNKRKRFMR----PT--QE-NPQ-GGVIEVEAPIHISNVM-FYDPKK-------KKKAG --VRVGFET----V--------KGKVR---VSRPDK---KEL--MGQKVNPIGLRIG--IT-RGWDSIWFS------Q-S D--YKKNLHEDIKIRKFV--QNRFN-----NAGVVKVVIERFP-E-KINVNLHTAKPGIVIGQKGANIEAVKKILKTMVN LNIIEVKK---PETVAQCIAESIALQIEQRQPFRRVMKQELRRAMRG-GVEGIKILISGRLNGADMARRENYKEGRIPL- -HTLRAKIDLGFKEAKTTFGQIGVKVWTYMSMSDPIGDMLTRIRNAGRAKHETCLV-PGSKIKKSILDLMKEEGFIKDYE SVK---VN---E----TFEDYKVFLKYD---HTK-------R---PIIRELVRVSTPGRRVYIKSAEIRPYKNNIGTLIV STSKGIMTGKNARKLKLGGEVILKMSMAGQKIRVKLKAFDHRLIDQSTYEIVATAKRTGATVSGPIPLPTKKEIYTVLRS PHVNKKSR-EQFELKTHKRLIDILDTNEDTVEALMKLQLPAGVSVDIKSSLLYEGRVVSNSMNKTVVILVETRKTHPKFK KIVRRSVRLKVHDEK--NECVVGDKILAIETRPLSKEKRHRLYKIVEKA------------------------------- -MARSV-KKGPFIDD-HLMKKITKLNS---ENQKK----PFKTWSRRSTIFPDMVGHTVMVHNGKQFTPVYINE-NMIGH KLGEFSPTRTFRGHV------A--GDK----KAA------KK >P_Leptospirillum_ferrodiazotrophum Concatenation of 2 sequences MGIKTYNPVPQSSRYKTGYTFEE-ITKE------------KP-YKPLTTSKKSSGGRNNIGTLTSRH-RGGGHKRA---- YRLIDFK-R--NK-DSIPAKVESIEYDPNRSARIALICYA-DGSRAYILAPIGLNVNDTVISGL-G-AD-IRPGNALEIM QIPLGTLVHNIEFKIGAGGKIARSAGAYAQILGR--EGDWVIIKLSSGETRKIHGRCRATVGQVGNIEHENISIGKAGRS -RWL-----GKR-P-HVRGVAMNPVDHPLGGGEGKS-S--GGRH-PCSP---WGQPSKGFKTR-HNPK-TD-R-FIIRRR --------------------------------MNS-----IIGEKIGMTQIYL-PNGK---------SIPVTVVKVGPCE VIQVK----TKE----K--DRY--SAVQLGY-------GI--VLNK----------PLRGHFK----------------- ---YS-QNTYRTIREVVI---------LGDPP-----PS---GS-IYGA--D-F-FKPGELVSATGMTKGKGFAGVMKRH HFRG-GDATHGS-MFHRE-PGSIGSS-AYPS-RVLKNKKLPGHMGHKKVTIKNLEVVEVKAEAN---------------- ----------LVLLKGA-VPGHPGTILVFK--MNIPVLS-SDGKSS-STISIDSEVT----QD-SFNN-GIVHEITTMEL AGMRAGTSSTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---SR-AP----QW---- RGGAIIFGPR-P-RNYFYKQPSKKVLKALREALLVRVSEN----------------K-VSIIPNL----ESE-T------ --LKTKLII--SEELD--E---NTWLSSRNIPGLT-I---------------LPSTAVTALYMVFTDV----VLVAEDSR EWLQPRLKKKYFLEI----QKALMNELKLSNVMQVPKIQKITLNVALG-EAIGNPKLLDMAAKEVGLITGQKPVLTKARK SIAGFKLREGMPIGVMVTLRGDIMWEFLDRLISIALPRIRDFKGVND-RSFDGNGNYSLGLKEQIIFPEIK-----YDEI TMSHGFDISIVTT-----------------------AKDNATAKALLTHLGMPFMSRIG-K--KPIQVPKGVTVK-I--- -D----KLNLHIKGPHGEMHHTL-PHG----FSVSQEN-DL--LTV---VR-P--SDNGKDK-ALHGLHRSLINNMVTGV AQPFKRVLEISGVGY--RAQLSG-QN--LSMT--LGFTKPVEMTL-P-P-QVKGTVE--K-QTVITLTS-FDKELLGQFS SEIKQAK------PVEPY---KGKGIRFEGEKVRRKEGK----------MIQLRTILQVADNSGAKKVMCFHIMG-SRRR Y--AHLGDTIVVSIKEATPN-A-------SVKKGDVAKAVVVRTVKEARREDGSYIRFDQNAAVLIN-AQGD-PIGTRIF GPVARELR-KRKFMKILSLAPEVIMK-F--HDLKPADGA-KHRKKRVG-RGIGSGH-GKTSTKGHKGQGARSGGT-K--- -PLGF-E-GGQTPLFLRIPK-RG--FTPINISRLVNIENLLDL-NVIKVK---------ILG--NGE-P-S-K-P-YFI- DGISMSRTVEEKILRTGGAI-K---MMK--GNL---KGKA-YRGSELSFG----------DYGLKAI--EPHWLTSRQIE AGRIAITRFV------KRGGKVWIRVFPDKPITRKPAETRMGSGK---------GNPEFWVAVIKP-GRIIYEM--EG-- VTPEVAEEALRLASYKMPFATKI-VRNEKRLSKHARVRKKI---KGSPERPRLSVYRSLKYIYAQIIDD---T--TGSTL VSASSLTMSEA---------KSG-DTVDVAKKVGEVLATE--AKKKN-ITSVVFDRGGYLYH--GRIKALADGARSGGLQ F-------------------------------------------------------------PGE-AVAKNRFIKVSPRK VRFVIDAIRGMDVVKAQSYLTFT---------------------------------RRGPAPIVLKTLNSAVSN----A- QQKF-LGESKDLKIEKIFVDQGPIMKRIQARAMGRAYSIKKRMSHLTIVLTRFPALKKDDKVIVTAGK------DK-GKV GKIIKVDRLYH--HVY--VENINMIKKAIK----PN--QT-SRE-GGFITKENFLNASNVM-LECPHC-------HK--P --TRIAHKF---FE--------NGKSR---ICKKCN---EVI--MGQKVHPTGFRLG--YI-KTWNSRWYA----K-K-- S--YVEWLHEDLQIRKYI--KKKLY-----QAGISRIDIERTG-K-DSRVLIHSAKPGLIIGKKGSEIEKLKSDLAKSLS ISIKEVKK---PEVDAQLVAESIASQLEKRISFRRAMKKSVASALRF-GALGVKICCAGRLGGAEIARTEWYREGRVPL- -QTIRADIDLGLAESYTTFGKIGIKVWVYMSLTDPIADMLTRIRNANMRVYQTVSC-QHSNLKENILKVMMEEGLISSYE VKE----T---E----GKKSLEIHLRVS---KER-------V---PLIRGLKRISKPGLRIYQKVSNHKSLMGGIGVTII STSKGVMTDRKAKQLNLGGEVLCQIW--MDKIRIRLKGYDFRILDQSLVDIVSTAKRTGATIKGPIPLPTRIEKFTVLRS PHADKKSR-EQFERRTHKRLIDIIESTPETIDALMKLELPAGVDVEIKLPRQLQGVVVKNKMMKTVVVEIRRKVVHPLYK KVITKKNRLKAHTEE---QIPQGATVLIAETRPISKDKHHRVVRVL---------------------------------- -MPRSI-KKGPFIDA-SLLEKVEKSIS---LGEKK----MIKTWSRRSMIIPEMIGFTFSVHNGKKFIPVYVTE-NMVGH KLGEFSPTRLFKAHG------GSKVEK----SSK------R- >P_Leptospirillum_ferrooxidans_C2-3 Concatenation of 2 sequences MAIKTFNPTSPAMRYKTGYSFDE-ITSD------------KP-FKPLTKGKISCGGRNNKGKTTVRH-RGGGHKRA---- FREIDLK-R--VK-DGIPAKVESIEYDPNRTARIALICYL-DGARSYILAPVGLKVGDTVLSGP-G-AD-IKPGNCLELS QIPVGTIIHNIEFKIAAGGKIARTAGTYCQILGR--EEDYVIIKMPSGEMRKIHGRCRASIGQIGNLEHENISIGKAGRT -RWL-----GKR-P-SVRGVAMNPVDHPLGGGEGKS-S--GGRH-PVSP---WGQPSKGFKTR-TNQR-TD-K-FIVRRR --------------------------------MNT-----LLGRKLGMTQIYL-ENGL---------SVPVTVVEAGPCE IVQVK----KHA----V--DGY--NAVQLGF-------DV--VINK----------PERGHQK----------------- ---YA-KDLYRILKEVRV---------QDESF-----ES---GT-IFTV--E-M-FKEGEFLDVTATTKGKGFAGVMKRH HFRG-GDATHGS-MFHRE-PGSIGSS-AYPS-RVLKNKKLPGHMGAKRVTVKNLKVIAVKPEAN---------------- ----------LLFLKGA-LPGATGSLVFVN-------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MLLAVREALLSHLKEQ----------------T-LQVIDGI----ELP-T------ --RKTKLIV--AVTLT--E---EVYFSGRNIPGLE-I---------------LLPHQLNPYDILLADS----ILITKEAY PMVAPRLRQKYDSEI----SKELVASLKLKNVMEAPKLRKITINVALG-EAVANPKILDTAVKELEAITGQKAVKTKAKK SIAGFKLREGMPIGTMVTLRGNIMWEFLDRFVSIALPRIRDFKGLND-KSFDGRGNFTTGLKEQIIFPEIK-----YDEV SMFHGMDICFTTT-----------------------AKNDVEGRTLLKLLGIPFMSRIG-K--KPIAIPLGVVVI----- -E-K-EK-TLEFKGPHGTLTHEL-PDG----FTLDKKD-NE--LTL---IR-P--SDERKDK-SFHGLHRSLIANKIQGV NEPFKKVLELVGIGY--RAQLNG-SV--ISLN--VGFTHPVEMPL-P-A-GVKASIE--K-QTVITLTC-SDKQLLGQFA ADIRGIK------PPEPY---KGKGIKYSGEKILRKEGK----------MIQLRTILEVADNSGAKKVMCFHVMG-SRRA Y--AHLGDTIVVSVKEATPN-A-------TVKKGDVAKAVVVRTVKEARRDDGSYIRFDQNAAVLIN-AQGE-PIGTRIF GPVARELR-KRKFMKILSLAPEVIMK-I--HDLSPAPGS-THRKKRVG-RGPGSGH-GKTSTKGHKGQHARSGGV-K--- -PPGF-E-GGQMPLVLRIPK-RG--FTPYNLSRLVSYETLADL-GILKVK---------ILG--NGE-V-S-K-A-YII- EDLEVSVSAKEKIESAGGQV-K---MMK--GNL---KGKA-YRGSELSFG----------EYGLKAL--EPIWLTARQIE AGRIAINRYV------KRGGKVWIRVFPDKPITKKAAETRMGSGK---------GNPEYWVAVVKP-GRIIFEM--EG-- VTPEVAEAALRLASYKMPMATKI-VRASTRKMKHTRVRKKI---QGTPERPRLTVFRSLKYIYAQVIDD---K--SGHTL VSASSLVNSTA---------KSK-DSVLAAKEVGLTLGSL--AKEKN-IQKVVFDRGGYIYH--GRIKALAEGAREAGLE F-------------------------------------------------------------MAS-AIAKNRYIRISPRK VRYVANAIRGKSVLEAMSILEVT---------------------------------TRGATKVVQKTLKSAVSN----A- IDLK-IATPETLHIQEIFVDVGPVAKRIQPRAMGRAYSIKKRTSHLTIIVSNFPPIKKNDKVKVLSGK------DK-GKE GQVLKVDRTNN--KII--VEDINKITKAVK----PD--QK-NPQ-GGFVVKENFLNASKVM-VICPSC-------KK--T --TRISHIT---LP--------TGKVR---SCKHCS---EHI--MGQKVHPIGFRLG--YI-KTWNSRWYA------Q-K G--FADLLHEDLKIRKVV--KAKLF-----HAGIAKIDIERTG-K-DARITIHTAKPGLIIGKKGLEIEKLKSELETQVS ISIKEIKK---PELEAQLIAESIAAQLEKRISYRRAMKKSVSSALRF-GALGVKIRCAGRLGGAEIARTEWYREGRVPL- -HTLRADIDFGFAEAATTFGKIGVKVWVYMSMTDPIADLLTRIRNANMRLHAQVNC-QHSKIKEEICRILKEEGFISSYS VEE----Q---N----SKKDLLISLRYV---KDR-------K---KILTGIKRISSPGLRVYRKSDEHKSLMGGLGVTIL TTSKGVMTDTKAKSENLGGEVICQVW-MDQKIRIRLKGYDYRLLDQSLVDIVSTAKRTGAIVKGPIPLPTKIEKFTVLRS PHVDKKSR-EQFERRTHKRLLDILDPTPETVDALMKLELPSGVDVEIKLIATLQGIVVSNKMMKTVVVEVRRRVLHPLYH KVVSKRSRIKAHTEE---QIDIGTEVQLMSTRPISKDKSFKVIKIVSKP------------------------------- -MPRSI-KKGPFVDQ-HLLDKVLKTSP---SQDRK----IIKTWSRRSMILPEMIGLTFSVHNGKKFIPVYITE-NMVGH KMGEFSPTRLFKAHG------GSKVEK----SAK------R- >P_Leptospirillum_rubarum Concatenation of 2 sequences MAVKKYNPTSPASRYKTGYSFEE-ITSD------------KP-YKPLTEPLISSGGRNNKGKLTSRH-RGGGHKKS---- YRIIDFK-R--SK-DGIPARVESIQYDPNRSARIALICYA-DGERNYILAPVGLNVNDIVQSGP-G-SD-IKPANCLELA QIPLGTIVHNIEYKIGAGGKIARTAGSYAQILGR--ESDYVILKMPSGEMRKIHGRCRATIGQVGNLEHENISIGKAGRS -RWL-----GKR-P-HVRGVAMNPVDHPLGGGEGKS-S--GGRH-PCSP---WGQPAKGFKTR-SNPR-TD-S-FIIRRR --------------------------------MKT-----LLGRKLGMTQIYL-PSGQ---------AVPVTIVEAGPCE VLQVK----TSE----K--EGY--SAAQIGY-------FP--VLNK----------PERGHQK----------------- ---YA-KNLYRYVREFKV---------EENTQ-----AP---GN-ILTV--E-I-FQEGDSLDITGQSKGKGFAGVMKRH HFRG-GDATHGS-MFHRE-PGSIGSS-AYPS-RVLKNKKLPGHMGDKRITVKNLKLIAVKPEAN---------------- ----------LLFIKGA-IPGSNGSFVVVN--MDIQMVA-LKDDSL-KSLEINVSAE----EA-ELINIPLLHEIIKMQR AGIRSGTASTKTRGE--------VS-GGGKKPY---------RQKGTGRAR--------QGS---TR-AP----QW---- RGGAIIFGPR-P-RDYFYRQPAKKVVLAVKNAIFSHLENK----------------S-LYVVDSL----DVP-S------ --RKTKLII--DNGLS--E---NIYYSCRNIPGLE-I---------------LLPHQVNPYDLLIADK----VLVSKEAF ENMNPRLKKKYEDSI----RSALIKELSLKNVMEAPKLSKITINVGLG-EAVANPKLLDSAVKELELISGQKAVKTRARK SIAGFKLREGMPIGSMVTLRGNKMWEFLDRFISIALPRIRDFKGLND-KAFDGRGNYTTGLREQIIFPEIK-----YDEV SLFHGMDITFSTT-----------------------ARTDNEGRALLKHLGIPFMSRIG-K--MPIIIPSSVQAK-E--- -ENG----ILTFKGPFGELKHKL--PQ-G--FSIEKQG-NS--LFL---KR-P--SDDPGHK-AFHGLHRTLIANKVKGV SEQFKKVLELNGVGY--RAQLNG-TT--LSLS--VGFTHTVEFTL-P-S-LIKASIE--K-QTIITLSS-PDKELLGQFA ADVRSIR------PPEPY---KGKGIKYSGEKILRKEGK----------MIQLRSILEVADNSGAKKVMCFHIMG-SRRR Y--ASLGDTIVVSVKEATPN-A-------SVKKGDVAKAVVVRTVKEVRRIDGSYIRFDQNAAVLIN-AQGE-PIGTRIF GPVARELR-LRKFMKILSLAPEVIMK-I--HDLYPAPGS-NKRKKRVG-RGPGSGH-GKTSTKGHKGQHARSGGV-K--- -PPGF-E-GGQMPLILRIPK-RG--FKSFNIATLVSAETLLKA-GLVKIK---------ILA--EGE-P-T-K-A-YKI- QDLEISKSAQEKIESAGGSV-----MMK--GNL---KGKA-YRGSELAFG----------DYGLKAL--EPVWLTARQIE AGRIAITRYV------KRGGKVWIRVFPDKPITKKPAETRMGSGK---------GNPEYWVAVIKP-GRIIFEM--EG-- VSPEIAQEALRLASYKMPMATKI-VRLYVRKSKHQRVRKKI---KGTSERPRLTVFRSLKYIYAQLIDD---S--VGRTI VSASSL------KGFS----GSR-DSSETAKEVGKLIGKL--AMEKN-IQKVVFDRSGYLYH--GRIKALAEGARESGLQ F-------------------------------------------------------------MAT-AIAKNRYIRIAPRK VRYVADAIRGKSVNEAFALLNVT---------------------------------TRGAVRIVEKTLKSAVSN----A- VEKK-IGSPSDLKVSEIFVDVGPIAKRMQPRAMGRAYSIKKRTSHLTIIVSVFPALRKNDKVKVISGK------DR-GKE GLILKIDRSSN--RLI--VENVNQITKAIK----PD--QN-HPQ-GGFITRENYLGVSKVM-LVCPGC-------HK--P --TRISHAI---LS--------DGKVR---VCKHCQ---EHI--MGQKVHPIGFRLG--YI-KTWSSRWYA------Q-K G--FADLLHEDLKIRKMV--KKKLF-----HAGIAKIEIERTG-K-DARISIHTARPGLIIGKKGLEIEKLKSELEETVS INIKEIKK---PELEAQLIAESVASQLEKRISYRRAMKKSVSSALRF-GALGVKICCAGRLGGSEIARTEWYREGRVPL- -HTLRADIDFGFAEASTTFGKIGVKVWVYMAMTDPIADLLTRIRNANMRLYERVSC-QHSKIKEELLKILLEEGFISSFE TLE----T---D----GKKDLHIKLKYV---KDR-------E---RVLKGIKRISTPGLRVYRKAQDYKSLMGGVGITII STSKGLMTDSKAKSLHIGGEVICQVW-MDQKIRIRLKGYDYRLLDQSLLEIVSTAKRTGASVKGPIPLPTKIEKFTVLRS PHVDKKSR-EQFERRTHKRLLDILEPTPETVDALMKLELPSGVDVEIKLISQAQGVVVGNKMMKTVVVEIQRRVLHPLYH KVVSRRTRIKAHTQE---PIEVGSVVEIISTRPISKDKSHRVLRVISTP------------------------------- -MPRSI-KKGPFVDL-HLMEKVSKSQN---ANDRK----MIKTWSRRSMIVPEMIGFTLSVHNGKKFIPVYVTE-NMVGH KLGEFSPTRLFKSHG------GSKVEK----SAR------K- >P_Thermodesulfovibrio_yellowstonii_DSM_11347 Concatenation of 2 sequences MGIRRCKPTSAGRRFVTYHDFSE-ITKD------------EP-YKPLTTCIKKRKGRNNQGRITSWL-KGGGNRKL---- YRIIDFK-R--NK-HGIPAKIESIQYDPNRSARIALLKYM-DGEYRYILAPDGLKVGDTIMSGS-G-ID-IKVGNALPLK EIPLGTMIHNIELFPNGGGKLVRSAGTAAQLMAK--EGKYAHVKLPSGEVRLINVNCFATIGQVSNLEHENVIIGKAGRT -RHM-----GRR-P-SVRGVAMNPIDHPLGGGEGKS-S--GGRA-ACTP---WGKPE-GVKTR-KNKR-TD-K-FIIKRR --------------------------------MKA-----ILGKKIGMTQIFD-EEGR---------IIPVTVIEAGPCW IVQVR----SKE----K--NGY--EAVQLGF-------QEIKKVPK----------PLLGIFK----------------- ---AG-IPPCRVLKEFKM-----------TGF-----NV---GD-KVTV--E-I-FTKGDVVSIAGISKGKGYQGVMKRH NFAG-GPDTHGS-MFNRA-PGSIGAS-SFPS-RVWKGKGMAGHMGNERVTVKNLTIVDVIPEQN---------------- ----------LLLVKGA-VPGGENGILQIW-MIEIEIRD-INNNIV-GKKEVPDIVF----NN-SA-SESVVHTAVVAYM ANQRQGTHCTKTRSE--------VS-GGGKKPW---------RQKHTGRAR--------HGS---IR-SP----LW---- RKGGIVFGPK-P-RDYYIQLPKQMKDTALFKALTMKYRDN----------------E-ILLLDNL----SLN-R------ --IKTKLIA--LPEKD--E---KVLLSARNIPYIG-V---------------VRAEDLNAYHVAMFDK----VVFTVAGL DKLLPRLKNKYDREI----IPALMKKFNYKNIMEVPRLEKIVVHVTLG-EAIQNIKLLDAAEKQLALITGQKPLVTKAKR ALAAFKLKKGMPLGCKVTLRKERMYEFLDKLISLALPRIRDFRGISP-KSFDGRGNYSFGIKEQFIFPEID-----YDKV EMIHGLDITICTT-----------------------AKTDEEALALLKEFGMPYMSRIG-R--KPIQIPDNVNVT-V--- -E-N--R-QIIVKGPKGQLSYSL--PE-G--IGITIDN-KT--MLI---TR-E--SDLSKQR-ALHGLARSLISNMVTGV SQGFTKALQIYGVGY--RAQVSG-NK--IILN--IGYSHPVEFVL-P-E-GIKATVD--EKQTTITLHG-IDKQLVGQIA ANLRAIR------PPDAY---KGKGIRYTDEVLKLKPGK----------MIQPRSILEVADNSGAKRVQCIRVLG-SNRK Y--ASLGDVIIVSVKEALPD-S-------NIKKGSVAKAVIVRLRRSVRRNDGSYIRFDQNAVVLVN-NQLE-PIGTRIF GPVARELR-WKEFTKIVSLAPEVIMK-I--NDLKPAPGS-KKKAKRIG-RGLGSGH-GRYATKGLKGQKSRSGGA-K--- -GAGF-E-GGQMPLQRRVPK-RG--FSNVNLEDLITPETLLQK-GIVKLK---------ILG--NGE-I-K-K-S-ITV- KTNAISKSALQKIQSVGGKV-K---MQK--GRM---NGIA-YRGSTVSFG----------EYGLKVL--EPAWITARQIE AARVAIMRHA------KKGCKLWIRIFPDKPITRKPAETRMGKGK---------GNPEFWVAVVKP-GRILFEL--SG-- VSEEIAKEAFELASHKLPVKTKF-VKTELRDRRRQRIRKKV---FGTSERPRLCIFRSLNHIYAQIIDD---T--KGHTL VAASTL-DKEL-KDLK----GHK-GNKEFAKKVGELIAER--AIKLG-ITKVVFDRAGYKYH--GCVKALADAARERGLQ F--------------------------------------------------------------ME-ARAILRYARITPTK ARRVMNLIRGKKAGEALLTLKYM---------------------------------PHKGARIIEKVLRSALAN----A- EQKNPRLDIDNLKIVKACVDQGPMMKRIEHRAMGRANIIKKKTSHITIYVGISLRIKKGDTVMVLSGK------DK-DKK GRVLVIMPKKE--KLV--VEGVNIVKKHQK----PS--RK-YPQ-GGIIEKEFPIYISKVM-LVCPKC-------DK--P --TRIGARI---LE--------DGKVR---VCKKCK---EVI--MGQKTNPIGNRLG--II-RTWESRWFA------K-K G--YADQLIEDLKLRKML--KDKLY-----HAGISKIEIERVG-E-KVRVLIFAARPGIIIGKKGAEVERLKKEVEEKAN IEIKEVRR---PELDAQLVAENVALQIEKRVAYRRAMKRAVASSMRF-GAKGIKVSCAGRLAGAEIARTEWYREGRVPL- -STFRADIDYGFAEAKTTYGIIGVKVWIF-MITDPISDMLTRIRNAIKVKADKVDI-PASRMKIEISKILKEEGFIKSYK IIK----D---K----KQGIIRINLKYT---SEG-------D---SVISNLQRISKPGRRVYVSKDEIPHVMGGLGVAIL TTSQGVMTDKECRHKGVGGEVICYIW-MDQKIRIKLRAYDNRVLDQSVKEIVDTVKKTGARISGPVPLPTKISKYTVLRS TNQDKKSR-EQFEIRVHKRLIDIHDPTPETVEALMKLELSAGVDVEIKLKKILKGTVVSDKMDKTVVVSVERVFQHPLYK KTIKTRKKYKAHDEE--NICQLGDMVEIIESSPISKTKRWKVLRIVKEG------------------------------- -MPRSL-KKGPFVDV-KLMEKVKKALE---SGDKK----PIKTWSRRSTIIPEFIGLTFAVHNGRKFIPVYVTE-NMIGH KLGEFAPTRTFKGHA------GSEEKK----KAK------GK >P_Treponema_denticola_ATCC_35405 Concatenation of 2 sequences MALKEYKPMTPGLRGRIDLRKDE-ITAQ------------KP-EKSLTTGKKNRAGRDSRGRISVRG-QGGGHKQK---- YRQIDFK-R--NK-YGIPGTVRTIEYDPNRSANIALIFYA-DGEKRYIIAPKGLKIGQKIMSGE-M-AT-LDVANALPLE AIPVGFTVHNIELTIGRGGQMARSAGAGALVAAK--EGEYVTIRLPSGETRLVNKKCYATIGEVGNEDHMNTSLGKAGRS -RWL-----GIR-P-TVRGMAMNPIDHPLGGGEGRG----KGRH-PVTP---WGQPCKGYKTR-KKRNPSD-S-FIVSRR ---------------------------------MI---G-LIGKKIGMTQIFN-EVGH---------LMPVTVIQVEPNT VVALK----DKE----K--FGY--SSVVLGL-------GE--LTSK----------PYAGQF------------------ ---SGDIKPLKLLKEFRD---------FDKEV-----AV---GD-KLGV--E-A-FEKVSYLDITAISKGKGFQGVMKRW GYGG-GRASHGS-KFHRE-AGSTGHC-TTPG-RSFKNTTMPGRMGFDKVTVQNLQIVKIDPELG---------------- ----------VIMVRGS-VPGKKDATVFLK--MEKKVYS-VDGKEL-RTINLDDKVF----GL-PV-NDDVIYYAINNEL ANKRVGTACTKGRAE--------VH-GSNSKPY---------SQKGTGRAR--------RGD---KK-SP----LL---- VGGGTIFGPK-P-RDFSYSMPKKAKRLAMKSILSLKAQND----------------R-LVVVEDF----TVE-S------ --GKTRVII--LKDDD--S---LVKRAGRNIPHLS-F---------------LAYNRLRAHDLFYGRK----VIMLESAA KNLSPRLKKVYTEQI----MPELKKEFNYSSVMQIPRLKKVVVSMGVG-VALTNRKLLDAAVTDLETITGQKAVKTKARK SIANFKLREGNEIGAMVTLRGARMYEFLDRFINVALPRVKDFRGVNP-NGFDGRGNYSVGITEQIIFPEID-----FDKI ERISGLNVNVVTS-----------------------AETDQEARSLLAKFGMPFMSRVG-K--MPVAIPAGVKVN-V--- -A-N-G--IFTVEGPKGKLSQDY-HTE-A--VDFKIEG-DH--VLV----T-R--KDDLQTR-AYHGLYRSLLNNMVTGV STGFTKTLVINGVGY--RAEVQG-KL--LVMA--LGYSNDFSVII-P-E-GIEVKVD----QLKVIISG-ASKEAVGQFA SQVRKLR------GPEPY---KGKGIRYEDEIIKRKVGK----------MIQVETRLNVADNSGAKLVECIKVIG-SKRR Y--AGIGDIIVVAVKEALPT-S-------VIKKGTVEKAVIVRVSKEYRRPDGTYIRFDDNACVIVD-DNKN-PKGKRIF GPVARELR-DHDFMKIVSLAPEVLMF-E--FNLTVPAGA-THKKKIVG-RGSSSGW-GKTSGKGHKGQQARSGGK-V--- -YAGF-E-GGQMPLYRRVAK-KG--FSNVNLAMLVNKESLMQK-GLLRVK---------VLG--TGD-I-T-K-K-LTV- DVDRISASAKEKIEKAGGTIMK---VQR--GRI---KGEA-TRCNNIDFG----------DYALVSL--EPFLLTNRQIE AARVALNRKI------KRGGKLWIRVFPDKPYSKKPAEVRMGGGK---------GAPEYWVAVVKP-GTIIFEL--AG-- VDKNLAEQAMTLAGSKLPFKTRF-AKDRKRFKRKMHIRKSI---FGTAERPRMTVFRSNKRISVQVIDD---V--EGKTL AAVSTM-EEAL-RSLK--------VNVESGAKVGEEIGKR--LKEKN-IDTVVFDRNGYLYH--GVVKAVADGARKTGIK F-------------------------------------------------------------ERTGYRATTKFLIASPTK VRPVANVVKNKPYPEAMAILENM---------------------------------PQKGAVLISQTMKSAASN----AL YKNK-QLDEDMLFVKEIMIDEGPRLKRIWCRGKGRADILLKRMCHITVVVDEKMKIRRNDSVEIIAGK------ER-GKR GEVVKVLQEDN--KVI--VGGLNMIKKAMR----KR-SQQ--DQ-GGIVEIEAPISASNVM-VICKKC-------GK--- --TRIAYEI----K--------DGKTR---ICRKCG---EAL--MGQKVNPTGLRLG--IN-KTWSSRWYA----G-P-R N--YADLLLEDLKIRAMIQEIPECK-----NADIAEVEIIRHP-Q-RITIMIHTARPGVIIGVKGANIENIGAIIQKKVQ IKIKEVKR---AELRAALVAQNVARQLAGRASFRKVLKQACFNTMRS-GAQGIKIRISGRLGGAEMSRTEEMKEGRVPL- -HTLRADIDYGFAEADTTYGKIGVKVWLYMSVSDPIADMLTKIRNAASAGHESVDV-PSSKMKWEIISILKSEGYIKNFK KMT----Q---E----GAGNIRVFLKYD---DKE-------S---SVIHGIERVSTPGRRVYLGYKSLPRVFNGYGTLIV STSKGIITGKAAGESQVGGELICKVWMTKEKIRVKLRGFDVELVDQSSKAIVQAVQKAGAKVCGPIPLPTRINKFTVLRS PHVNKKSR-EQFEMRTHKRLIDIIEPSAEVMNALLALELSAGVDVEIKQKREFVGIVTSDKMNKTIVVEVRTKKLHKLYK KYVSSSKKYKAHDEE--NTAHIGDTVRIVEHKPISKDKAWMLTEVIERA------------------------------- -MSRSV-KKGPFIAK-SLFKNVNEMNR---SGKKK----PIKTYSRCSTIIPEMVGNTISVHNGKTWIPVYITE-NLVGH KLGEFAPTRTFRKHA------N--SDK----KVG------K- >P_Treponema_pallidum_pallidum_Nichols Concatenation of 2 sequences MALKMYRPMTAGLRGRVDLCRAE-LTAR------------TP-EKSLTRGKPAKAGRGAGGRISVRH-RGGGHKRR---- YRDIDFK-R--DL-HDIPGTVKTIEYDPNRSVNIALVFYA-NGQKRYILAPKGLKVGQQVVSGE-K-VP-LEPANALPLG VIPVGFTVHNVELTIGKGGQIARSAGTRAVIAAK--DGGYVMLRLPSGEARLVHRRCYATIGELGNEDHMNTALGKAGRA -RWR-----GVR-P-TVRGMAMNPVDHPLGGGEGRG----KGRN-PVTP---WGQPCRGYKTR-KKRRVSD-R-FIVSKR ---------------------------------MV---G-LIGQKVGMTQIFD-ARGC---------VTPVTVIRVEHNV VVGLK----DVE----R--FGY--SAVILGT-------GC--MISK----------PYAGQFR----------------- ------IPPVRVMREFRG---------FTLDV-----SV---GQ-VLDV--R-V-LESVRYLDVCALSKGKGFQGVVKRW GFSG-GRSSHGS-KFHRE-AGSTGQC-TSPG-RTFKNVKMPGRMGAERVTVQNLRIERIDVGLG---------------- ----------VVMVRGA-VPGRNKATVFLR--MEKTVYS-VEGVAL-RSVELDESVF----GL-SV-NRGVIYYAINSEL SNKRLGTACTKGRSE--------VH-GSNTKPY---------KQKGTGRAR--------RGD---KK-SP----LL---- VGGGTIFGPK-P-RDFHYALPKKVKRLAMKSLLSLKAQGD----------------A-LTVIEDF----TVE-S------ --GKTRVFI--LQNDD--A---LLKRAGRNIPTLS-F---------------LSYNRLRAHDLFYGRK----VLVLETAV HKIAPELKVRYVQQI----VPDMMRDFGYSTVMQVPKLLKIVLSMGLG-EALANRKLLDASVADLGVISGQHAVKTRARK SIANFKLREGNEIGVMVTLRRSRMYEFLHRLINVALPRVKDFRGVSP-XGFDGHGNYSMGITEQIIFPEID-----FDKI ERISGLNVNVVTS-----------------------AQTDQEARTLLTKLGMPFMSRIG-K--VPVSVPGGVHVR-V--- -SSG----VVEVEGPKGVLSCAF--LP-V--VTVRVEQ-EY--VIV---AR-C--DDSKRAR-ACHGLYRKLLSNMVVGV SEGFSKTLVITGIGY--RAEVQG-RV--LVMA--LGYSNDFTVLI-P-S-GIEVRVE--S-STRVIVSG-VSKERVGEFA AQLRRLR------LPEAY---KGKGIRYDYETIVRKVGK----------MIQVQSRLNVADNSGARLVQCIKVVG-SRRR Y--ASVGDIIVVAVKDALPT-S-------VIKKGSVEKAVIVRVSKEYRRVDGTYIRFDDNACVVID-ANGN-PKGKRIF GPVARELR-DMDFTKIVSLAPEVLMA-D--FHLIAPKGA-NRARRIVG-RGSSSGR-GTTSGRGTKGQQARAGHK-A--- -YVGF-E-GGQMPLYRRVPR-RG--FSNVNVGALVNRQTLIEK-GLVKIK---------ILA--DGE-L-T-K-S-IVV- RVDRVSARAQEKIQQAGGSVMK---VQR--GRV---KGDA-TRCNAVDFG----------AYALVCL--EPFWLTSRQIE AARVALNRRI------KRGGKLWIRVFPDKPYSKKPAETRMGKGK---------GSPEYWVAVVKP-GTVLFEL--MG-- VERALAEQAMLLAGSKLPIKTRF-AKQRKRMKRKVHIRKRV---YGTAVRPRMTVFRSNRNISVQVIDD---D--ARSTL ASVSTL-EKDF-VLLR--------ANVSSGLQIGEEIGRR--LLEKH-IDTVIFDRNGYLYH--GVVAAVADGARKAGVK F-------------------------------------------------------------ERVTYRAKTKFLVASPTK VRPVANVVKCKPYVRAMALLGHL---------------------------------PHKGARLISKVMKSAASN----AI DRDK-RLDEERLFVRDIQIDEGPRLKRLWCRGRGRGDVQLKRMCHITVVVEETVKIRKDDMVLVIAGK------DR-GKR GAVLRVLRDVD--RVL--VQGLNMRKKTIR--------RKSAQDEGGIMEVEAPIHISNVM-IMGKKG-----------P --TRVGYRM----E--------NGKVR---VCRKTG---EVL--MGQKVSPIGLRLG--IN-KVWSSRWYA------GPR E--YAALLHEDLRIRSMIRSFPECK-----NADIAEVEIVRHP-Q-RVTVVMHTARPGVVIGAKGVNIEKIGAEVQKRVQ IKVKEIKR---MELNAYLVAQNVARQLTARVSFRKCLRQACAGTMKS-GAQGVKIRVSGRLGGAEMSRTEEIKEGRTPL- -HTLRADIDYGFAEAHTTYGSIGVKVWLYMGVSDPVADMLTKIRNAARAGHEKVDV-PSSKLKVEVVKILKTEGYIRNFR KVE----E---D----GSGCIRVFLKYD---DNE-------T---SVIHGIERISTPGRRVYSGYKTLRRVYNGYGTLIV STSLGVTTGRHAREQRVGGELICKVWMARERIRVKLCGFDVELVDQSSRAIVHAVQKAGAEVLGPIPLPTRMHKFTVLRS PHVNKKSR-EQFEMRTHKRLIDIIEPSQEVMNALMGLELSAGVDVRIKQRRTLVGLVTSDKMHKTVTVRITTKKLHALYK KYVSRSKKYQAHDEE--NTARAGDVVRIAESRPLSRRKRWRLVEIVERA------------------------------- -MSRSV-KKGPFVDK-KLYKRVVEMNK---AANQR-NKKVIKSYSRCSTIIPEMVGFTISVHNGKSWIPVYITE-EFVGH KLGEFSPTRVFRGHS------G--SDK----KVG-------R >P_Treponema_pallidum_pallidum_SS14 Concatenation of 2 sequences MALKMYRPMTAGLRGRVDLCRAE-LTAR------------TP-EKSLTRGKPAKAGRGAGGRISVRH-RGGGHKRR---- YRDIDFK-R--DL-HDIPGTVKTIEYDPNRSVNIALVFYA-NGQKRYILAPKGLKVGQQVVSGE-K-VP-LEPANALPLG VIPVGFTVHNVELTIGKGGQIARSAGTRAVIAAK--DGGYVMLRLPSGEARLVHRRCYATIGELGNEDHMNTALGKAGRA -RWR-----GVR-P-TVRGMAMNPVDHPLGGGEGRG----KGRN-PVTP---WGQPCRGYKTR-KKRRVSD-R-FIVSKR ---------------------------------MV---G-LIGQKVGMTQIFD-ARGC---------VTPVTVIRVEHNV VVGLK----DVE----R--FGY--SAVILGT-------GC--MISK----------PYAGQF------------------ ---AERIPPVRVMREFRG---------FTLDV-----SV---GQ-VLDV--R-V-LESVRYLDVCALSKGKGFQGVVKRW GFSG-GRSSHGS-KFHRE-AGSTGQC-TSPG-RTFKNVKMPGRMGAERVTVQNLRIERIDVGLG---------------- ----------VVMVRGA-VPGRNKATVFLR--MEKTVYS-VEGVAL-RSVELDESVF----GL-SV-NRGVIYYAINSEL SNKRLGTACTKGRSE--------VH-GSNTKPY---------KQKGTGRAR--------RGD---KK-SP----LL---- VGGGTIFGPK-P-RDFHYALPKKVKRLAMKSLLSLKAQGD----------------A-LTVIEDF----TVE-S------ --GKTRVFI--LQNDD--A---LLKRAGRNIPTLS-F---------------LSYNRLRAHDLFYGRK----VLVLETAV HKIAPELKVRYVQQI----VPDMMRDFGYSTVMQVPKLLKIVLSMGLG-EALANRKLLDASVADLGVISGQHAVKTRARK SIANFKLREGNEIGVMVTLRRSRMYEFLHRLINVALPRVKDFRGVSP-XGFDGHGNYSMGITEQIIFPEID-----FDKI ERISGLNVNVVTS-----------------------AQTDQEARTLLTKLGMPFMSRIG-K--VPVSVPGGVHVR-V--- -SSG----VVEVEGPKGVLSCAF--LP-V--VTVRVEQ-EY--VIV---AR-C--DDSKRAR-ACHGLYRKLLSNMVVGV SEGFSKTLVITGIGY--RAEVQG-RV--LVMA--LGYSNDFTVLI-P-S-GIEVRVE--S-STRVIVSG-VSKERVGEFA AQLRRLR------LPEAY---KGKGIRYDYETIVRKVGK----------MIQVQSRLNVADNSGARLVQCIKVVG-SRRR Y--ASVGDIIVVAVKDALPT-S-------VIKKGSVEKAVIVRVSKEYRRVDGTYIRFDDNACVVID-ANGN-PKGKRIF GPVARELR-DMDFTKIVSLAPEVLMA-D--FHLIAPKGA-NRARRIVG-RGSSSGR-GTTSGRGTKGQQARAGHK-A--- -YVGF-E-GGQMPLYRRVPR-RG--FSNVNVGALVNRQTLIEK-GLVKIK---------ILA--DGE-L-T-K-S-IVV- RVDRVSARAQEKIQQAGGSVMK---VQR--GRV---KGDA-TRCNAVDFG----------AYALVCL--EPFWLTSRQIE AARVALNRRI------KRGGKLWIRVFPDKPYSKKPAETRMGKGK---------GSPEYWVAVVKP-GTVLFEL--MG-- VERALAEQAMLLAGSKLPIKTRF-AKQRKRMKRKVHIRKRV---YGTAVRPRMTVFRSNRNISVQVIDD---D--ARSTL ASVSTL-EKDF-VLLR--------ANVSSGLQIGEEIGRR--LLEKH-IDTVIFDRNGYLYH--GVVAAVADGARKAGVK F-------------------------------------------------------------ERVTYRAKTKFLVASPTK VRPVANVVKCKPYVRAMALLGHL---------------------------------PHKGARLISKVMKSAASN----AI DRDK-RLDEERLFVRDIQIDEGPRLKRLWCRGRGRGDVQLKRMCHITVVVEETVKIRKDDMVLVIAGK------DR-GKR GAVLRVLRDVD--RVL--VQGLNMRKKTIR----RK-SAQ--DE-GGIMEVEAPIHISNVM-IMGKKG-----------P --TRVGYRM----E--------NGKVR---VCRKTG---EVL--MGQKVSPIGLRLG--IN-KVWSSRWYA------GPR E--YAALLHEDLRIRSMIRSFPECK-----NADIAEVEIVRHP-Q-RVTVVMHTARPGVVIGAKGVNIEKIGAEVQKRVQ IKVKEIKR---MELNAYLVAQNVARQLTARVSFRKCLRQACAGTMKS-GAQGVKIRVSGRLGGAEMSRTEEIKEGRTPL- -HTLRADIDYGFAEAHTTYGSIGVKVWLYMGVSDPVADMLTKIRNAARAGHEKVDV-PSSKLKVEVVKILKTEGYIRNFR KVE----E---D----GSGCIRVFLKYD---DNE-------T---SVIHGIERISTPGRRVYSGYKTLRRVYNGYGTLIV STSLGVTTGRHAREQRVGGELICKVWMARERIRVKLCGFDVELVDQSSRAIVHAVQKAGAEVLGPIPLPTRMHKFTVLRS PHVNKKSR-EQFEMRTHKRLIDIIEPSQEVMNALMGLELSAGVDVRIKQRRTLVGLVTSDKMHKTVTVRITTKKLHALYK KYVSRSKKYQAHDEE--NTARAGDVVRIAESRPLSRRKRWRLVEIVERA------------------------------- -MSRSV-KKGPFVDK-KLYKRVVEMNK---AANQR-NKKVIKSYSRCSTIIPEMVGFTISVHNGKSWIPVYITE-EFVGH KLGEFSPTRVFRGHS------G--SDK----KVG------R- >THERMI_Deinococcus_deserti_VCD115 Concatenation of 2 sequences MAVKKYRPYTPSRRQMTTADFSG-LTKK------------RP-EKALTEALPKTGGRNNRGRITSRF-IGGGHKRL---- YRIIDFK-RR-DK-SGVSARVAAIEYDPNRSARIALLHFA-DGEKRYILAPEGLQVGATINTGP-E-AE-PKLGNALPLR FIPVGAVVHALELVPGKGAQLARSAGTSVQVQGK--ESEYVIVRLPSGELRRIHTECYATIGAVGNAEHKNINLGKAGRS -RWL-----GRK-P-HQRGSAMNPVDHPHGGGEGRT-G--AGRQ-PVSP---WGQLAKGLKTR-RKRKNSD-R-FIVTRR ---------------------------------MK---G-ILGTKVGMTQIW--KGDR---------AVPVTVVLAGPCP VVQRK----TSV----S--DGY--EAVQIGF-------AP--KVNR----------PAAGHFK----------------- ---YG-VSPVRFLREFRN-------------F-----NPD--GD-TVSV--D-I-FAEGEKIDATGTSKGKGFQGVMKRW NFKG-GPASHGSKKWHRR-PGSIGQR-KTPG-RVYKGKRMAGHMGMDRITVQNLEVVEVRADEN---------------- ----------LILVKGA-IPGANGGLVVLR-MAQINVIG-KNGGRT-IDLELPE--------V----NAAILHDVVTWQL ASRRRGTASTKTRAQ--------VS-KSGKKMY---------SQKGTGNAR--------HGD---RG-VP----TF---- VGGGVAFGPK-P-RSYGYTLPRKVRQLGLAMALADRQDGG----------------K-LIAVDGF----DLD-------- --GKTKLIV--TDDA-------QTRQSARNVAWAT-V---------------LPVAGLNAYDILRHDR----LVIDAVAL EPAQQTLKTKYNEQV----RPALMQQFGYSSVMAVPRIEKIVINEGLG-SSKEDSKAIDKAARELGLITLQKPIITKAKK SISNFKLRQGMPVGVKVTLRNERMYVFLEKLINIGLPRIRDFRGINP-NAFDGRGNYNLGIKEQLIFPEIT-----YDMV DKVRGMDITIVTT-----------------------AKTDEEARALLQAMGLPFMSRIG-K--QPIAVPSGVTVN-T--- -Q-S--G-VFKVKGPKGELTVPF-NPD----LTIREDN-GQ--LLV---ER-P--SDRQEHR-ALHGLTRTLVANAVKGV SDGFVINLELRGVGY--RAKLNG-KA--LELT--IGYSHPVVIDP-P-A-GVTFAVP--E-PTKIDVSG-IDKQLVGQVA ANVREVR------KPDAY---HGKGVRFVGQQIALKAGK----------MIMPQSRLDVADNSGAREIMCIRVLG-GNKR Y--AHVGDIIVASVKDAAPR-G-------AVKAGDVVKAVVVRTSHAIKRADGSTIRFDKNAAVIIN-NQGE-PRGTRVF GPVARELR-DRRFMKIVSLAPEVLMK-L--HELKPAEGS-RKNRKRVG-RGPGGT--DKTAGRGHKGQKSRSGAG-K--- -GSFF-E-GGRSSLISRLPK-RG--FNNIQLGQLFNREALELA-GLVRVK---------LLA--TGE-V-T-R-A-VTV- HVDAASAAAVKAVEAAGGKVMK---QHR--GRM---TGDA-KGGDYVAFG----------DYGLIAL--EPAWIRSNQIE ACRIVMSRHF------RRGGKIYIRIFPDKPVTKKPAETRMGKGK---------GAVEFWVSVVKP-GRVMFEV--AG-- VTEEQAKEAFRLAGHKLPIQTKM-VAAQTSIRRKLRARRKV--RIAAGERPRLSVFRSSKHIYAQIIDD---K--NGTTL AAASSA---VV---------KAG-NKTDTAAAVGKALAEA--ASAKG-VKQVVFDRGQYKYH--GRVKALADAAREGGLD F-------------------------------------------------------------RTP-GKAIAKYVRMSPRK VRLVVDVIRGKSVSDAEAILRFL---------------------------------PKSASEPVAKVLNSAKHN----A- LHND-EMLEDRLVITAAYVDAGPTLKRLIPRARGSANILKKRTSHITIIVGEKLHVKKGDTVVVLSGK------HK-GKT GKVLLALPRDQ--KVI--VEGVNLVTKHVK----PS--AS-NPQ-GGIEQREGALHASKVS-IVDPET-------GK--A --TRIRKQI----V--------DGKVR---VAVASG---KVI--MGNKINPNGFRLG--IT-RGWNSRWYA------GKK Q--YAGLLKEDEKIRKLV--DKKLS-----AAGIARVEIERAG-Q-QVNVIISAAKPGIVIGKGGDSIKQLRADIEKLVA VNVAEIPN---PNISAPLVALRIAEQIERRFAFRRAMKQAAQRVMES-GARGVKVVLSGRLGGAEQARRETVREGRVPL- -HTLRADIDYGTALARTTYGILGIKVMVF-MLSDPIADMLTRIRNATRTHKETVDV-PASNFKEQLANLLVAEGYVAGVE RTR-LD-G---Q----PADVLRLTLKYG---AKR-------E---QVIKHIERISRPGRRAYVSAENLPRIQRGMGVAVV STSKGLLPDREARKLGVGGEVICVLWMVAPKIRIKLRGFDHKALDQSASKIVDTVRRTGADVSGPVPLPTRIRRFCVLRS PFKYKDAR-EHFEIRTHNRLVDIMNPTKKTIDSLMTLDLPTGVDIEIKTKKTFTGVVVSDKADKTVSVKVERRFAHPLYG KVVTRSHKYAAHDEN--NEFKIGDRVEILAVRPISKTKTWKVTKLIERP------------------------------- -MPRSL-KKGPFVDD-HLLKKVDAQNE---RKDKR----VIKTWSRRSTIVPEMIGHTIAVHNGKQHVPVFVNE-QMIGH KLGEFSPTRSYRGHG------A---DK----NAK---GSKKK >THERMI_Deinococcus_geothermalis_DSM_11300 Concatenation of 2 sequences MAVKKYRPYTPSRRQMTTADFSG-LTKK------------RP-EKALTVPLPKTGGRNNHGRITSRF-IGGGHKRL---- YRIIDFK-RR-DK-ANVPAKVAAIEYDPNRSARIALLHYV-DGEKRYILAPEGLTVGQTVNAGP-E-AE-PKLGNALPLR FVPVGAVVHAVELVPGKGAQLARSAGTSIQVQGK--ERDYVILRLPSGELRRIHSECYATIGTVGNAEHKNIVLGKAGRS -RWL-----GRK-P-HQRGSAMNPVDHPHGGGEGRT-G--AGRV-PVSP---WGQPAKGLKTR-KKRKISD-R-FIITRR --------------------------------MTK---G-ILGTKIGMTQIW--KGDR---------AVPVTVVLAGPCP VVQRK----TKL----T--DGY--EAVQLGF-------AP--KVNR----------PELGHFK----------------- ---AG-VAPMRFLREFRD-------------F-----APE--GD-TVNV--D-I-FAEGEKIDATGTSKGKGTQGVMKRW NFAG-GPASHGSKKWHRR-PGSIGQR-KTPG-RVYKGKRMAGHMGMERVTVQNLEVVEVRADEN---------------- ----------LILVKGA-IPGANGGLVMLR-MAQINVIG-QNGGRS-IDLDLPE--------V----NPHVLHEVVTWQL AGRRRGTASTKTRAE--------VS-RSGKKMY---------SQKGTGNAR--------HGD---RS-VP----TF---- VGGGVAFGPK-P-RSYSYTLPRKVRQLGLAMALADRQQQG----------------K-LTAVDGF----GLD-------- --GKTKLIV--TDDE-------LTRRAARNVAWAT-V---------------LPVAGLNVYDILRHER----LVIDAVAL EPAQQTLKAKYNEQV----RPALMQQFGYSSIMAVPRIEKIVINEGLG-SSKDDSKAIDKAAKELALITLQKPVITKAKK SISNFKLRQGMPVGVKVTLRGERMYVFLEKLINIGLPRIRDFRGINP-NSFDGRGNYNLGIKEQLIFPEIT-----YDMV DKVRGMDITIVTT-----------------------AKTDEEARALLQAMGLPFMSRIG-R--QPIAVPNGVTVN-A--- -Q-N--G-VFTAKGPKGELSVPY-NTA----LNITQEN-GQ--LLV---TR-P--SDRQEHR-ALHGLTRTLVANAVKGV SDGYTINLELRGVGY--RARLVG-KN--LELT--IGYSHPVVIEP-P-A-GVTFAVP--E-PTRIDVMG-IDKQLVGQVA ANVRKVR------KPDAY---HGKGVRFVGEQIALKAGK----------MIMPQTRLDVADNSGARELMCIRVLG-GNKR Y--AHVGDIIVASVKDAAPR-G-------AVKAGDVVKAVVVRTSHAIKRADGSTIRFDKNAAVIIN-NQGE-PRGTRVF GPVARELR-DRRFMKIVSLAPEVLMK-L--HDLTPAPGS-RKPKKRVG-RGPGGT--DKTAGRGHKGQKSRSGAG-K--- -GPFF-E-GGRSTLISRLPK-RG--FNNVNLAQLLDRTALERA-GLVRVK---------LLA--RGQ-V-T-R-A-VTV- QVDAASEAAIRAVEAAGGRV-K---QFR--GRM---TGDT-KGGDYVAFG----------DYGLVAL--EPAWIKSNQIE ACRIVMSRHF------RRGGKIYIRIFPDKPVTKKPAETRMGKGK---------GAVEYWVSVVKP-GRVMFEV--SG-- VTEEQAREAFRLAGHKLPIQTKM-VASQTAIRRKLRARRKV--REAAGERPRLSVFRSNKHIYAQIIDD---R--SGTTL AAASSS---AV---------KTG-TKTDTAAAVGRALAEA--AVAKG-VKQVVFDRGAYKYH--GRVKALAEAAREGGLD F-------------------------------------------------------------RRP-GYAIAKYVRMSPRK VRLVVDVIRGKSVAEAEDLLRFI---------------------------------PRAASEPVAKVLKSAKSN----A- INND-EMLEDRLVVAAAYVDAGPTLKRLLPRARGSANIIKKRTSHITIIVAEKLHVKKGDTVIVLRGK------HK-GQT GKVLLALPRDA--KVV--VEGVNLVTKHVK----PS--AA-NPQ-GGIEQREAALHASKVA-LVDPET-------GK--P --TRVRKAI----V--------DGKVR---VAVKSG---KVI--MGNKINPNGFRLG--IT-KGWNSRWYA------GKK Q--YSQLLKEDEKIRKLV--SQKLA-----AAGIARIEIERAG-Q-QVNVIISAAKPGIVIGKGGESIKQLRGEIERLVA VNVAEIPN---PNISAPLVALRIAEQIERRFAFRRAMKQAAQRVMES-GARGVKVILSGRLGGAEQARTEKVLEGRVPL- -HTLRADIDYGTARAETTYGSLGIKVLVF-MLSDPIADMLTRIRNATRAYKESVDI-PASKFKEELAKLLVREGYVAGVE RLR-PE-G---Q----KFDVLRITLKYG---QKR-------E---QVIKHIERVSRPGRRAYVSAENLPRVQRGLGLAVV STSKGLLPDREARKQGVGGEVVCILWMVAPKIRIKLRGFDHKALDQSASKIVDTVRRTGADVSGPVPLPTRIRRFTVLRS PFKYKDSR-EHFEIRTHNRLVDIMNPTKKTIDSLMTLDLPTGVDIEIKTKKTFTGVVVSDKADKTVSVKVERRFMHPLYG KVVTRSKKYAAHDEQ--NEYRIGDRVEIIAVRPISKTKTWKVTRLIERP------------------------------- -MPRSL-KKGPFVDD-HLLKKVDAQNE---RREKR----VIKTWSRRSTIVPEMIGHTIAVHNGKQHVPVFINE-QMIGH KLGEFSPTRTYRGHG------A---DK----NAK---GSKKK >THERMI_Deinococcus_radiodurans_R1 Concatenation of 2 sequences MAVKKYRPYTPSRRQMTTADFSG-LTKK------------RP-EKALTEALPKTGGRNNRGRITSRF-IGGGHKRL---- YRIIDFK-RR-DK-SGVNAKVAAIEYDPNRSARIALLHYA-DGEKRYILAPEGLTVGATVNAGP-E-AE-PKLGNALPLR FVPVGAVVHALELVPGKGAQLARSAGTSVQVQGK--ESDYVIVRLPSGELRRVHSECYATIGAVGNAEHKNIVLGKAGRS -RWL-----GRK-P-HQRGSAMNPVDHPHGGGEGRT-G--AGRV-PVTP---WGKPTKGLKTR-RKRKTSD-R-FIVTRR ---------------------------------MK---G-ILGTKIGMTQIW--KNDR---------AIPVTVVLAGPCP IVQRK----TAQ----T--DGY--EAVQIGY-------AP--KVNK----------PMQGHFK----------------- ---AG-VAPTRILREFRG-------------F-----APD--GD-SVNV--D-I-FAEGEKIDATGTSKGKGTQGVMKRW NFAG-GPASHGSKKWHRR-PGSIGQR-KTPG-RVYKGKRMAGHMGMERVTVQNLEVVEIRAGEN---------------- ----------LILVKGA-IPGANGGLVVLR-MAQINVIG-QNGGRT-IELPLPE--------V----NSGVLHEVVTWQL ASRRRGTASTRTRAQ--------VS-KTGRKMY---------GQKGTGNAR--------HGD---RS-VP----TF---- VGGGVAFGPK-P-RSYDYTLPRQVRQLGLAMAIASRQEGG----------------K-LVAVDGF----DIA-D------ --AKTKLLV--TDDE-------NTRRAARNVSWVS-V---------------LPVAGVNVYDILRHDR----LVIDAAAL EIVEQQLKTKYNDQV----RPALMQQFGYSSVMAVPRIEKIVVNEGLG-SSKEDSKAIDKAAKELALITLQKPIITKAKK SISNFKLRQGMPVGIKVTLRGERMYVFLEKLINIGLPRIRDFRGINP-NAFDGRGNYNLGIKEQLIFPEIT-----YDMV DKTRGMDITIVTT-----------------------AKTDEEARALLQSMGLPFMSRIG-K--QPIAVPSGVTVN-A--- -Q-D--G-VFKVKGPKGELTVPY-NTE----LTVRQDG-DQ--LLV---ER-P--SDAQKHR-ALHGLTRTLVANAVKGV SDGYTINLELRGVGF--RAKLTG-KA--LEMN--IGYSHPVIIEP-P-A-GVTFAVP--E-PTRIDVSG-IDKQLVGQVA ANVRKVR------KPDAY---HGKGVRFVGEQIALKAGK----------MIMPQSRLDVADNSGAREIMCIRVLG-GNKR Y--AHVGDIIVASVKDAAPR-G-------AVKAGDVVKAVVVRTSHAIKRADGSTIRFDRNAAVIIN-NQGE-PRGTRVF GPVARELR-DRRFMKIVSLAPEVLMK-L--HDLKPTPGS-RKDRKRVG-RGPG-GT-DKTAGRGHKGQKSRSGAG-K--- -GAFF-E-GGRSRLIARLPK-RG--FNNVKLSQLFDRDTLEAY-RLVRVK---------LLA--SGE-I-S-R-A-VTV- HVDAASAAAIKAVEAAGGRVMK---QFR--GRM---TGDA-KGGDYVAFG----------DYGLIAM--EPAWIKSNQIE ACRIVMSRHF------RRGGKIYIRIFPDKPVTKKPAETRMGKGK---------GAVEYWVSVVKP-GRVMFEV--AG-- VTEEQAKEAFRLAGHKLPIQTKM-VATATTIRRKLRTRRKVRTTTAASGRLRLSVYRSSKHIYAQIIDD---S--RGQTL AAASSA---AL---------KSG-NKTDTAAAVGKALAAA--AAEKG-IKQVVFDRGSYKYH--GRVKALADAAREGGLD F-------------------------------------------------------------RKP-GFAVAKYVRMSPRK VRLVVDVIRGKSVQDAEDLLRFI---------------------------------PRSASEPVAKVLNSAKAN----A- LHND-EMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKLHFKKGDTVIVLSGK------HK-GQT GKVLLALPRDQ--KVV--VEGVNVITKNVK----PS--MT-NPQ-GGQEQRELALHASKVA-LVDPET-------GK--A --TRVRKQI----V--------DGKVR---VAVASG---KTI--MGNKINPNGFRLG--VT-KGWNSRWYA------G-K K-QYASLLKEDEQIRQLI--NKKLA-----AAGIARIEIERAG-Q-QVNVIISAAKPGVVIGKGGESIKELRGDIERLVA VNVAEIPN---PNISAPLVALRIAEQIERRFAFRRAMKQAAQRVMES-GARGVKVILSGRLGGAEQARTEKVLEGRVPL- -HTLRADIDYGTALARTTYGILGIKVLVF-MLSDPIADMLTRIRNATRTHKETVDI-PASKFKEELAKLLVREGYVQGVE RTR-PE-G---Q----KFDVLRVTLKYG---EKR-------E---QVIKHIERVSRPGRRAYVSAENLPRVQRGLGVAVV STSRGLLPDREARQQGVGGEVVCVLWMVAPKIRIKLRGFDHKALDQSASKIVDTVRRTGADVSGPVPLPTRIRRFTVLRS PFKYKDSR-EHFEIRTHNRLVDIMNPTKKTIDSLMTLDLPTGVDIEIKTKKTFTGVVVSDKADKTVSVKVERRFAHPLYG KVVTRSHKYAAHDEN--NEYKIGDRVEIIAVRPISKTKTWKVTKLIERP------------------------------- -MPRSL-KKGPFVED-HLLKKVDAQND---KKDKR----VIKTWSRRSTIVPEMIGHTIAVYNGKQHVPVFVNE-QMIGH KLGEFSPTRTYRGHG------A---DK----NAK---GSKKK >THERMI_Thermus_thermophilus_HB27 Concatenation of 2 sequences MAVKKFKPYTPSRRFMTVADFSE-ITKT------------EP-EKSLVKPLKKTGGRNNQGRITVRF-RGGGHKRL---- YRIIDFK-R-WDK-VGIPAKVAAIEYDPNRSARIALLHYV-DGEKRYIIAPDGLQVGQQVVAGP-D-AP-IQVGNALPLR FIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGR--EGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRS -RWL-----GRR-P-HVRGAAMNPVDHPHGGGEGRA-P--RGRP-PASP---WGWQTKGLKTR-KRRKPSS-R-FIIARR ---------------------------------MK---G-ILGVKVGMTRIFR--DDR---------AVPVTVILAGPCP VVQRR----TPE----K--DGY--TAVQLGF-------LP--QVNR----------PLKGHFK----------------- ---AG-VEPVRILREIRD-------------F-----NPE--GD-TVTV--E-I-FKPGERVDVTGTSKGRGFAGVMKRW NFAG-GPDSHGAHKIHRH-PGSIGNR-KTPG-RVYKGKKMAGHYGAERVTVMNLEVVDVIPEEN---------------- ----------LLLVKGA-VPGPNGGLVIVR-MYQIPVLS-PSGRRE-LAADLPA----------EI-NPHLLWEVVRWQL AKRRRGTASTKTRGE--------VA-YSGRKIW---------PQKHTGRAR--------HGD---IG-AP----IF---- VGGGVVFGPK-P-RDYSYTLPKKVRKKGLAMAVADRAREG----------------K-LLLVEAF---AGVN-------- --GKTKLLV--TGNE-------LVRRAARNLPWVV-T---------------LAPEGLNVYDIVRTER----LVMDLDAW EVFQLALKRKYYEEV----RPELIRRFGYQNVWEVPRLEKVVINQGLG-EAKEDARILEKAAQELALITGQKPAVTRAKK SISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNP-NSFDGRGNYNLGLREQLIFPEIT-----YDMV DALRGMDIAVVTT-----------------------AETDEEARALLELLGFPFMSRIG-R--LPIPVPKGVSVE-V--- -APG----RVKVKGPKGELEVPV--SP-E--MRVVVEE-GV--VRV---ER-P--SDERRHK-SLHGLTRTLIANAVKGV SEGYSKELLIKGIGY--RARLVG-RA--LELT--VGFSHPVVVEP-P-E-GITFEVP--E-PTRVRVSG-IDKQKVGQVA ANIRAIR------KPSAY---HEKGIYYAGEPVRLKPGK----------MIQPQTYLEVADNTGARKIMCIRVLG-SNAK Y--ATVGDVIVASVKEAIPR-G-------AVKEGDVVKAVVVRTKKEVKRPDGSAIRFDDNAAVIIN-NQLE-PRGTRVF GPVARELR-EKGFMKIVSLAPEVLMK-L--SDLRPNPGA-NKRRKRVG-RGPGSGH-GKTATRGHKGQKSRSGGLKD--- -PRRF-E-GGRSTTLMRLPK-RG--MQGVNLKDLVTPELLVRA-GLLKLK---------ILG--EGE---A-K-P-LKV- VAHAFSKSALEKLKAAGGEP-K---QQR--GRL---KGAT-KGGDYVAFG----------DFGLVAL--EPAWITAQQIE AARVAMVRHF------RRGGKIFIRIFPDKPYTKKPLEVRMGKGK---------GNVEGYVAVVKP-GRVMFEV--AG-- VTEEQAMEALRIAGHKLPIKTKI-VRLTAYERRKFRVRNRI----KRTGRLRLSVFRSLKHIYAQIIDD---E--KGVTL VSASSL-ALKL----------KG-NKTEVARQVGRALAEK--ALALG-IKQVAFDRGPYKYH--GRVKALAEGAREGGLE F--------------------------------------------------------------ME-AKAIARYVRISPRK VRLVVDLIRGKSLEEARNILRYT---------------------------------NKRGAYFVAKVLESAAAN----A- VNNH-DMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKMHVKKGDTVLVASGK------YK-GRV GKVKEVLPKKY--AVI--VEGVNIVKKAVR----VS--PK-YPQ-GGFIEKEAPLHASKVR-PICPAC-------GK--P --TRVRKKF---LE--------NGKIR---VCAKCG---GAL--MGNKIHPIGFRLG--IT-RDWESRWYA------GKK Q--YRHLLLEDQRIRGLL--EKELY-----SAGLARVDIERAA-D-NVAVTVHVAKPGVVIGRGGERIRVLREELAKLVA LNVQEVQN---PNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMES-GAKGAKVIVSGRIGGAEQARTEWAAQGRVPL- -HTLRANIDYGFALARTTYGVLGVKAYIF-MLTDPIADMLTRIRNATRVYKESTDV-PASRFKEEILRILAREGFIKGYE RVD----V---D----GKPYLRVYLKYG---PRRQGPDPRPE---QVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAIL STSKGVLTDREARKLGVGGELICEVW--MPKIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRG PFKHKDSR-EHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTKKVLTGVVVSDKMQKTVTVLVERQFPHPLYG KVIKRSKKYLAHDPE--EKYKLGDVVEIIESRPISKRKRFRVLRLVESG------------------------------- -MPRSL-KKGVFVDD-HLLEKVLELNA---KGEKR----LIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITE-NMVGH KLGEFAPTRTYRGHG------K--EAK----ATK------KK >THERMI_Thermus_thermophilus_HB8 Concatenation of 2 sequences MAVKKFKPYTPSRRFMTVADFSE-ITKT------------EP-EKSLVKPLKKTGGRNNQGRITVRF-RGGGHKRL---- YRIIDFK-R-WDK-VGIPAKVAAIEYDPNRSARIALLHYV-DGEKRYIIAPDGLQVGQQVVAGP-D-AP-IQVGNALPLR FIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGR--EGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRS -RWL-----GRR-P-HVRGAAMNPVDHPHGGGEGRA-P--RGRP-PASP---WGWQTKGLKTR-KRRKPSS-R-FIIARR ---------------------------------MK---G-ILGVKVGMTRIF--RDDR---------AVPVTVILAGPCP VVQRR----TPE----K--DGY--TAVQLGF-------LP--QVNR----------PLKGHFK----------------- ---AG-VEPVRILREIRD-------------F-----NPE--GD-TVTV--E-I-FKPGERVDVTGTSKGRGFAGVMKRW NFAG-GPDSHGAHKIHRH-PGSIGNR-KTPG-RVYKGKKMAGHYGAERVTVMNLEVVDVIPEEN---------------- ----------LLLVKGA-VPGPNGGLVIVR-MKEVAVYQIPVLSPS-GRRELAADLP----A--EI-NPHLLWEVVRWQL AKRRRGTASTKTRGE--------VA-YSGRKIW---------PQKHTGRAR--------HGD---IG-AP----IF---- VGGGVVFGPK-P-RDYSYTLPKKVRKKGLAMAVADRAREG----------------K-LLLVEAF---AGVN-------- --GKTKLLV--TGNE-------LVRRAARNLPWVV-T---------------LAPEGLNVYDIVRTER----LVMDLDAW EVFQVALKRKYYEEV----RPELIRRFGYQNVWEVPRLEKVVINQGLG-EAKEDARILEKAAQELALITGQKPAVTRAKK SISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNP-NSFDGRGNYNLGLREQLIFPEIT-----YDMV DALRGMDIAVVTT-----------------------AETDEEARALLELLGFPFMSRIG-R--LPIPVPKGVSVE-V--- -APG----RVKVKGPKGELEVPV--SP-E--MRVVVEE-GV--VRV---ER-P--SDERRHK-SLHGLTRTLIANAVKGV SEGYSKELLIKGIGY--RARLVG-RA--LELT--VGFSHPVVVEP-P-E-GITFEVP--E-PTRVRVSG-IDKQKVGQVA ANIRAIR------KPSAY---HEKGIYYAGEPVRLKPGK----------MIQPQTYLEVADNTGARKIMCIRVLG-SNAK Y--ATVGDVIVASVKEAIPR-G-------AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIIN-NQLE-PRGTRVF GPVARELR-EKGFMKIVSLAPEVLMK-L--SDLRPNPGA-NKRRKRVG-RGPGSGH-GKTATRGHKGQKSRSGGLKD--- -PRRF-E-GGRSTTLMRLPK-RG--MQGVNLKDLVTPELLVRA-GLLKLK---------ILG--EGE---A-K-P-LKV- VAHAFSKSALEKLKAAGGEP-K---QQR--GRL---KGAT-KGGDYVAFG----------DYGLVAL--EPAWITAQQIE AARVAMVRHF------RRGGKIFIRIFPDKPYTKKPLEVRMGKGK---------GNVEGYVAVVKP-GRVMFEV--AG-- VTEEQAMEALRIAGHKLPIKTKI-VRLTAYERRKFRVRNRI----KRTGRLRLSVFRSLKHIYAQIIDD---E--KGVTL VSASSL-ALKL----------KG-NKTEVARQVGRALAEK--ALALG-IKQVAFDRGPYKYH--GRVKALAEGAREGGLE F--------------------------------------------------------------ME-AKAIARYVRISPRK VRLVVDLIRGKSLEEARNILRYT---------------------------------NKRGAYFVAKVLESAAAN----A- VNNH-DMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKMHVKKGDTVLVASGK------YK-GRV GKVKEVLPKKY--AVI--VEGVNIVKKAVR--VSPK-----YPQ-GGFIEKEAPLHASKVR-PICPAC-------GK--P --TRVRKKF---LE--------NGKIR---VCAKCG---GAL--MGNKIHPIGFRLG--IT-RDWESRWYA------GKK Q--YRHLLLEDQRIRGLL--EKELY-----SAGLARVDIERAA-D-NVAVTVHVAKPGVVIGRGGERIRVLREELAKLVA LNVQEVQN---PNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMES-GAKGAKVIVSGRIGGAEQARTEWAAQGRVPL- -HTLRANIDYGFALARTTYGVLGVKAYIF-MLTDPIADMLTRIRNATRVYKESTDV-PASRFKEEILRILAREGFIKGYE RVD----V---D----GKPYLRVYLKYG---PRRQGPDPRPE---QVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAIL STSKGVLTDREARKLGVGGELICEVW--MPKIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRG PFKHKDSR-EHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTKKVLTGVVVSDKMQKTVTVLVERQFPHPLYG KVIKRSKKYLAHDPE--EKYKLGDVVEIIESRPISKRKRFRVLRLVESG------------------------------- -MPRSL-KKGVFVDD-HLLEKVLELNA---KGEKR----LIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITE-NMVGH KLGEFAPTRTYRGHG------K--EAK----ATK------KK >THERMO_Fervidobacterium_nodosum_Rt17-B1 Concatenation of 2 sequences MGLKRFKPTTPGRRFMIIPDFSE-ITKT------------KP-EKSLVVPLKKSAGRNHHGRVTVRF-RGGGHKRL---- YRIVDFR-R-WEK-ENIPAKVASIEYDPNRTARIALLIYA-DGEKRYILAPNGLNVGDTVMSGP-E-AE-IKPGNALPLE NIPVGTIVHSIEFLPRGGAKIARSAGVACQLMAK--EGNYALLKMPSGELRKVHIKCYATVGVVGNEDHKNEVSGKAGRE -RWK-----GRK-P-HVRGVVMNPVDHPHGGGEGRG----KGHH-PQSP---WGVPAKGYKTR-RGKRASD-K-FIVRRR --------------------------------MKF-----IIARKVGMTRLW--KDEK---------VVPVTVLKAGPCV VVQKK----TVE----K--DGY--NAIQLGF-------EE--VLTK----------PMLGVFK----------------- ---AN-VKPMRVLKEFRV--------ENVDQY-----SV---GQ-EITV--A-I-FQEGDKIDITGWTKGRGYSGAMKRW NFQG-GPKAHGA-KFHRE-LGSVGQH-TEPA-RIFKGKRMPGRYGNERVTILNSEVVTIDAQNN---------------- ----------LLAVKGG-VPGARGSLVIIR-MAQVTLYN-IKGEKI-GNIEIADEVF----NV-EP-NLDVMWRYIDMQL TNSRAGTASTKTRGE--------VA-GGGRKPW---------PQKHTGRAR--------QGS---IR-AI----HW---- RHGGVAHGPK-P-RNYLKRLNKKMKKLALKSALSARFQEG----------------N-LIVVSDI----RFE-K------ --AQTKLFV--LPRKE--EVYENVKLSGRNIPGVK-VIIADNPNNGNP----VNIDGLNVYDIINSSK----VVLTEGTV RKIEVPLKEKYQKEV----VPVLMKEFGYKNIHEVPRLVKVVINMGVG-EGSRNKDVIEAHARELTTIAGQKAIITKAKK SISNFKIRKGMSVGVKVTLRGPRMYNFVYKLVNLVLPKVRDFRGLNP-NSFDGKGNYSFGLTEQLVFPEIS-----PDQI KRIQGMDIVVVTT-----------------------AKRDEEARRLLELLGFPFMSRIA-K--KPIVLPTNVQLS-I--- -T-D--S-EIKVKGPKGELKLNN--HP-F--VSIKVEG-NE--VWV----T-P--NLERKFK-AMVGTYWRLIRNMVLGV TEGFKKELEIVGVGY--RAQLQG-NK--LIMN--LGYAHQVEFDV-P-A-DVKVEVP--A-PNKIIVSG-IDKQRVGQVA ADIRKWR------EPNPY---SGKGIKYVDEVLKLKEGK----------MIQNESYLVAADNSGAKVLRVIRVLG-SHKQ F--GTIGDIVVCSVREAVPN-T-------DIKKGDVVKAVVVRTKKEIRRPDGSYIRFDDNAAVVLD-KFNQ-PKGTRVF GPVARELR-EKGFMKIVSLAPEVWIT-I--EDLKPTPGS-NKKYKRLG-RGQGSGK-GKTAGKGHKGQKSRGTGK-V--- -RAWM-E-GGQTPLHRRLPK-FG--FKNVNLETLVTPEVLIEK-GIIDVK---------ILA--RGE-I-T-K-P-LTV- KAHKFSEKAKEKIEKVGGKI-K---QHR--GRT---KGDA-KGGALVMFG----------EYGLKAL--EPAWITAQQIE ACRLAITRTL------KKEGKLWIKIFPDKSYTKHPPETKLGKGK---------GNVEGWVAVVKP-GKVMFEI--GG-- VEEELAIKALEYAATKLPIKTKI-VRRQLRLVRHKRLRKKI---FGTPERPRLAVFRSEKHMYAQIIDD---T--KGITL VAASTV-EKAM-KEKL----QKT-WNITAAKEVGKLIAER--ALAKG-IKEVVFDRGGFKYH--GRVKALADAAREAGLK F-------------------------------------------------------------KYE-ARAVARFVRISPRK ARSVINSIRGKNVSEAFNLLEFS---------------------------------SKKAARIVYNVLKSAVAN----A- TNNL-GLSEENLYVAACYVNDGPRMKRVWPRGRGRADIIQKRMSHITVIVRDAQKIKKGDTVQVISGK------DK-GKR GEVIQVLPKEE--KLI--VRGVNIVKRHQR----PT--GQ-MRQ-GGIIEKEAPLYWSKVM-LVCPSC-------DK--A --TRVGFRV---LE--------DGKVR---YCKKCG---EII--MGQKVHPKGFRLG--LT-SEWDAQWFN------E-K K--YSEYLLEDEAIRNFI--KKNYN-----QAGIARVFVQRPDAE-RVLVSIYAARPGILIGKKGAGITELRQALEANFG IDIIELKT---PETEASLVAESIAQKIEKRASYKIVMKRAITAALRR-GARGIKIMVSGRLAGAEIARTEWYLKGRLPL- -QTLRSVIDYSTARAETKYGTIGIKVWIY-MWSDPIADMLTRIRNANQVFKEQVDV-PASNLKKAIADILVREGFIKGYT YIE----D---G----KQGILRIQMKYKGTRKNR-------E---RVIHGIVRVSKPGRRIYVGKNNIPRVKNGLGIAII STSKGVLTDKEAAEHGVGGEVIAYIWMPGQKIRIRLRAYDHRLLDESAKKIVEVAKQTNAKVSGPIPLPTERSLYVVLRS PLKHKDSR-EQFEKKVHKRLIDIIEPNSKTIDALMKINLPAGVDVEINLKKRLVGVVVSDKMDKTVTVKVERLVKHAKFG KYVKRTKKFYAHDEN--NACRVGDVVEIEESRPLSKLKRWVVVNILERS------------------------------- -MSRSS-KKGPFVDP-KLIKKIRMLNE---TGEKK----IIKTWSRASTIVPEMVGHTIAVYNGMKHIPVYITE-NMVGH KLGEFSFTRRFGGHT----------NK----SAK--KGEVKK >THERMO_Petrotoga_mobilis_SJ95 Concatenation of 2 sequences MALKQYKPVTPSRRYMTTSDFSE-LSKV------------EP-EKSLLEPLKKTGGRNHYGRVTMRH-RGGGHKRK---- YRIIDFK-R--DK-INIPAKVASIEYDPNRSARIALLVYA-DGEKRYILSPKGLHVGETVMSGA-K-AE-IKVGNSLPLE NIPLGTLVHNIEFEPGRGGKIAKSAGTYAQLMAK--EGKYALLKMPSGELRRVRLSCMATIGVVGNEEHSNEVYGKAGKT -RWL-----GRR-P-KVRGMVQNPVDHPMGGGEGRS----KGHI-PKSP---WGTPAKGYKTR-RGKKQSD-K-FIVRRR ---------------------------------MK---G-ILGKKVGMTRVF--KDDK---------AIPVTVIKAGPCV VVQKK----TVE----T--DGY--NAIQIGF-------EE--IANK----------PLMGHFK----------------- ---AQ-VKPLRYLREFRV--------ENVDDY-----EI---GQ-KIDV--T-I-FSEGEKIDLIGNSKGRGYSGVMKRW NFRG-GENTHGS-KFHRG-LGSTGMA-TFPS-KVFKGKKMPGQYGNERVTIQNSEVVYIDVQNN---------------- ----------LIAVKGG-VPGARGGLVTIR-MSQIDIYN-IQNEKV-GTLDIKDEIF----NI-DP-NMDVLYRYVDMQL TNKRAGTASTKTRSE--------VS-GGGRKPW---------PQKHTGRAR--------AGS---IR-SP----LF---- RHGGVTFGPK-P-REFHKDLNKKMKRLALKSALSVRYREN----------------N-LIVLDEV----KFE-K------ --PRTKLFL--FPYHQ--EQYENFKLSARNLPKVK-VIIADNPGQNKK-----NVDGLNVFDLINSEK----IVLTKEMV NKIEIPLKDRYKEVV----IPSMMKEFNYKNELQVPKLVKIVVNMGVG-EGSRNRAVVEKHAQELTKIVGQKALIARAKK SVANFKVREGMPIGVKVTLRGWKMYNFLYKLNHVVLPKLRDFRGLPA-DSFDGRGNYTFGIPEQLIFPEIR-----PDDI SRIQGMDITIVTT-----------------------AKTDEEARKLLEYFGFPLQSRIA-D--KPTIIPDGVELS-V--- -D-G--Q-TIKIKGKNGELSLNL--PE-Y--LEVDRDN-NE--LMI----K-T--KEGKRLK-ALRGTFTSHVRNMIKGV TEGYKKELEIAGIGY--RAQLQG-KN--LILN--IGYSNPVEFPV-P-E-GITIEVP--Q-PTIVVVKG-IDKYKVGEVA ARIRSLR------KVNVY---SGKGIKYVGESVLRKEGK----------MVQLESKIRVADNSGAKVLRVIKVLG-FHKS K--GTVGDTVVCSVREAIPH-T-------DLKKGQVVQAVIVRTKKEIRRKDGTYIRFDDNAAVLID-KNKL-PLGTRVF GPVAREVR-EKGYAKIASLAKEVWLK-I--EDLKPTPGS-RKPKKRLG-RGIGSGL-GKTAGKGHKGEKARGRGK-I--- -GRTF-E-GGQTNIIRRTPK-FG--FSNVNVETLVTPDILLEK-KLIKVK---------ILG--KGE-I-S-K-P-LVV- KANIFSQTAREKIEAVGGKI-K---QQR--GTV---RGMT-KGASLVHFG----------DWGLKAM--ESSWITAQQIE ACRLSMVRTL------KRTGNIWINIFPDKPITSKGIGTRQGKGK---------GDVEGWVAVVKK-GRVMFEI--GG-- VDEATAKRALEYAASKLPIRTKI-VKKALRQKRHLRVRKNV---RGTSEKPRLTVFKSQKHIYAQIIDD---T--KGVTL ASASTT-QKQL-KEKL----EKT-WDENAAKEVGKLIAEK--AKEKG-ITEIVFDRSGYKYH--GKVKALAEAARETGLK F-------------------------------------------------------------IVE-ARAVTKYVRISPRK ARSMANSIRNKDISEALQILTFS---------------------------------PKKSARILYKTLMSAIAN----A- ENNF-GLNAENLYVSEIMVNEGPRLKRLWPRSHGRADILQKRMSHIYITVRDMYKIKRDDTVVVISGK------DK-GKR SKVLRVIPKDK--KVI--VDNVNVVKKHQR----PT--QK-MRE-GGIIEQPSPIDISNVM-LVCPNC-------NQ--K --TRVGFKF---LE--------DGKVR---YCKKCG---EIV--MGSKVHPNGFRLG--NN-KTWKSVWFN------E-K N--YSDYLHEDEKIRDYI--KSNYE-----AAGISEILIERPS-DSSIRIDIYGARLGILIGRKGAEMKKIRDDLKNIIK VYAEEVKN---PYVVAQLIAEDVSGQLQRRVSHKVAMKRAITNAMRR-GAKGVKIMVSGRLGGAEIARTEWYMEGRLPL- -QTLRSNIDYAVVHSQTKYGTIGIKVWVY-MWSDPVADMLTRIRNANSVFKESVEI-PASNLKKDILEIMKKEGFINDYK FID----D---G----KQGILKVYLKYKGTRRDK-------K---PIMEGIIRVSKSGRRVYVNTRNIPKVKGGLGIAIL STSQGVMTDKEAREKKVGGEVICYVWASNKYIKIRLKGYDHRLLDESSKKIIDAVKDTEAKVSGPIPLPNKRTVYSVIRS PHKYSYSM-EQFEKIVHKRVIYIYNASSDTVTKLLKVNIPAGVSVDIKAKKIITGKVVSNAMDKTITVETDRLTKHPKYH KFVRKTRRYHAHDEN--NECEIGDIVEIEESRKLSKTKAFVLKRIVRKN------------------------------- -MGRSL-KKGPYVHP-SLIKKIREMNE---KGEKK----VIKTWSRASMILPEMVGHTIAVHNGMKHIPVYITE-QMIGH RLGEFSPTRRFGGHP----------DK----KAVKGKIEKQG >THERMO_Thermosipho_africanus_TCF52B Concatenation of 2 sequences MGLRRFKPTSPARRQMIIPDFSE-ITKK------------EP-EKSLIAPLKKTGGRNSYGRVTVRF-RGGGHKRR---- YRIIDFK-R--DK-VGIPARVVSIEYDPNRTARIALLVYA-DGEKRYILAPQGLNVGDTVLNGP-D-AE-IKPGNALPLE NIPVGTIVHNVEFIPGKGGQIARSAGTSCQLMAK--EGKYALLRMPSGELRKVPVKCYATIGVVGNEDHKNEVDGKAGRV -RWK-----GRK-P-HVRGVAMNPVDHPHGGGEGRG----KGHH-PQSP---WGQLAKGYKTR-RGKKASD-K-LIVRRR --------------------------------MKM-----IIGRKVGMTRIF--KDDK---------VIPVTVIKAGPCY VVQKK----TID----T--DGY--NAIQIGF-------EE---VNK----------PMEGVFK----------------- ---AG-VKPLKILKEFRV--------ENPEEF-----EL---GQ-EIKV--D-I-FAEGDKIDITGWSKGRGFAGAMKRW GFRG-GPKSHGA-KFHRE-LGSVGQH-SEPA-RIFKGKKMPGQYGNERVTILNSEIVKIDVENN---------------- ----------LIAVKGG-VPGARGGLVLIR-MAKVSLFN-SKGENI-GPIDLKDEVF----AI-EP-NFDVIWRYVDMQL TNARAGTASTKTRGE--------VS-GGGRKPW---------IQKHTGRAR--------QGS---IR-AP----HW---- RHGGVAHGPK-P-RVYFKRLNKKMKRLALKSALSLRLKEG----------------N-LIVVDEI----KFK-R------ --PKTKLVV--LPKKV--EEYVNVKISGRNIPGVK-VIIADNPGV-DR----TNIDGLNVYDILNHDK----LVLLQGTV QKIEIPLKEKYENEI----KPAMMKEFGYKNIHQVPRLEKIVINMGIG-EGSRNKDVIDIHAKELALIAGQKPVVTKAKK SISNFKIRKGMPIGLKVTLRGVNMYNFLYKLINLVLPKVRDFRGLNP-NGFDGRGNYSFGLTEQLVFPEIS-----PDQV RRVQGMDIVIVTT-----------------------AKTDDEARKLLELFGFPFMSRIA-N--KPIVIPNGVEVK-V--- -E-G--N-VLKVKGPLGELKQDF--LP-Y--VKVEING-NE--MNV----K-P--NVDKKMK-MFTGTYWRLFNNMVIGV TKGFKKELEIVGIGY--RAQLQG-KK--LVMN--LGYAHPVEMEI-P-S-DVKVEVP--S-PNKIIVSG-IDKQRVGQVA ADIRKWR------EPNVY---SGKGIRYVGEVVRLKEGK----------MIINESYLNVADNSGAKLLRVIRVMG-SRRK W--GTVGDVVVCSVRDAVPN-G-------DLKKGDVVKAVIVRTKKEIRRPDGTYIRFDDNAAVVLD-KYNE-PKGTRVF GPVAKELR-EKGFMKIVSLAPEVFMR-L--SDIRPTPGS-MRKRIRVG-RGIGSGK-GKTSGKGHKGQKARGTGK-V--- -HPWF-E-GGQTPIHRRLPK-FG--FKNVNVEDLVTPEKLLEV-GLIKVK---------ILG--NGE-I-T-K-P-LTV- VAHAFSSSARRKIEAVGGKA-K---QHR--GRM---KGNA-KGGALVNFG----------EYGLKAM--ESHWITAQQIE ACRIAITRTL------KKTGKLWIRVFPDKSYTKHPAESKLGKGK---------GNVEGWVAVVKP-GKILFEI--GG-- VDEKLAREALEYAATKLPIRTKI-VRNWRRKKRHLSIRKKI---HGTADRPRLCVYKSEKHIYAQIIDD---D--KGHTL VAASTL-DKEL-RETL----KKT-WNKEAAREVGKLIGKR--AIEKG-IKKVVFDRGGYRYH--GRVAELAEGAREAGLE F-------------------------------------------------------------VYE-ARAVAKFVRISPRK ARSVANSIKGKNVSEAFTILEFS---------------------------------PKKAARLIKNVLKSAVAN----A- VNNH-GLNEENLYVYTCYVNDGPRMKRIWPRGRGSADIIQKRMSHITVIVRDARKIRKGDTVMVLSGK------DK-GKT GEVVRVIPKED--KVV--VRGVNVVKRHQR----PN--AQ-MRQ-GGIIEKESPIYACKVA-LVCPSC-------GK--A --TRVGFRF---LE--------DGKVR---YCKKCG---EVI--MGQKVHPRGFRLG--IT-ADWQATWFN------E-K N--YKEYLLEDEEIRKVI--KNKYA-----QAGISEIVIERPDSE-RVIAIIKSARPGIIIGKKGAEITELRQELEKRFI VNVEEIKN---PEVDAQLVAENIASRIEKRASYKVVMKKAIFNAMKK-GAKGIKIMVSGRLAGAEIARTEWYLKGRLPL- -QTIKSIIDYGTARAETKYGTIGIKVWIY-MWSDPIADMLTRIRNANVALKEQVDV-PASNLKKEIAEILKREGFIKDYT YIE----D---G----KQGIIRIHMKYKGTRRNR-------E---RVIHGIVRVSKPGRRIYVGKDNLPKVKNGLGIAIL TTSKGVLTDKQAREIGVGGEVIAYIWMPGQKIRIRLKAYDHKLLDESAKKIVEIVKQTNAKVSGPIPLPTERTLYVVLRS PLKHKDSR-EQFEKRIHKRLIDILEPSPKTIDALMKINLPAGVDVEINLKKKLIGEVVSDKMDKTVVVAVSTLVKHPRVG KYIKRTKKYYAHDEN--NECRDGDIVEIIESRPLSKLKRWRVLRIVERS------------------------------- -MGRST-KKGPYVDP-KLLKKIRQLNE---AGEKK----IIKTWSRASMIVPEMVGHTIAVYNGLKHIPVYITE-NMVGH RLGEFSFTRRFGGHA----------DK----SAS--KGQVKK >THERMO_Thermosipho_melanesiensis_BI429 Concatenation of 2 sequences MGLKRFKPTSPARRQMIIPDFSE-ITKK------------EP-EKSLIAPLKKTGGRNSYGRVTVRF-RGGGHKRK---- YRIIDFK-R--DK-VGIPAKVVSIEYDPNRTARIALLVYA-DGEKRYILAPQDLNVGDMVMNGP-D-AE-IKPGNALPLE NIPVGTVIHNVEYIPGKGGQIARSAGTSCQLMAK--EGKYALLRMPSGELRKVPVKCYATIGVVGNEDHKNEVDGKAGRV -RWK-----GRK-P-HVRGVAMNPVDHPHGGGEGRG----KGHH-PQSP---WGQLAKGYKTR-RGKKASD-K-LIVRRR --------------------------------MKM-----IIGRKLGMTRVF--VGDK---------VVPVTVIKAGPCF VVQKK----TIE----T--DGY--NAVQLGF-------EE---VNK----------PMEGVFK----------------- ---AG-VNPLKVLKEFRV--------EDPDKF-----EV---GQ-EIKV--D-I-FSEGDKIDITGWSKGRGFAGAMKRW GFRG-GPKSHGA-KFHRE-LGSVGQH-SEPA-RIFKGKKMPGQYGNERVTILNSEIVKIDVENN---------------- ----------LIAVKGG-VPGARGGLVLIK-MAKVDLFN-IKGENI-GTVELKEEVF----AI-EP-NQDVMWRYIDMQL TNSRAGTASTKTRGE--------VS-GGGRKPW---------IQKHTGRAR--------QGS---IR-AP----HW---- RHGGVAHGPK-P-RVYFKRLNKKMKRLALKSALSLRLKEN----------------N-LVVVDDI----KFE-K------ --PRTKLIV--LPKKE--SEYENVKISGRNIPGVK-VLIADNPGV-DR----VNIDGLNVYDILNHDK----LVLLQGTV QKIEIPLKEKYEKEI----RNAMMKEFGYKNIHQVPRLEKIVINMGIG-EGSRNKDVIDIHAKELALIAGQKPVVTRAKK SISNFKIRKGMPIGLKVTLRGLRMYNFLYKLINLVLPKVRDFRGLNP-NGFDGRGNYSFGLTEQLVFPEIS-----PDQV RRVQGMDIVIVTT-----------------------AKTDEEARKLLELFGFPFMSRIA-N--KPIVIPNGVEVK-V--- -E-N--N-VFKVKGPKGELSQEF--LP-Y--IKIEVNE-NE--IYV----K-P--NLEKKMK-MFTGTYWRLFNNMIIGV TQGFRKELEIIGIGY--RAQLQG-KK--LVMN--LGYAHPVEMEI-P-S-DVAVEVP--S-PNRIVVSG-IDKQRVGQVA ADIRRWR------EPNVY---SGKGIRYVGEVVRLKEGK----------MIINESYLNVADNSGAKLLRVIRVMG-SRRK W--GTVGDIVVCSVRDAVPN-G-------DLKKGDVVKAVIVRTKKEIRRPDGSYIRFDDNAAVVLD-KYNE-PKGTRVF GPVAKELR-EKGFMKIVSLAPEVFMR-L--SDIKPTPGS-MKKRTRVG-RGIGSGK-GKTSGKGHKGQKARGRGK-V--- -HPWF-E-GGQTPLHRRLPK-FG--FKNVNVEQLVTPEKLLEK-GVIKVK---------ILG--NGE-I-T-K-P-LTV- IAHAFSSSARRKIEAVGGKV-K---QHR--GRM---KGKA-KGGSLVAFG----------DYGLKAL--EAHWITAQQIE ACRIAITRTL------KKSGKLWIRIFPDKSYTKHPAESKLGKGK---------GNVEGWVAVVKP-GRVMFEI--GG-- VSEELAREALEYAATKLPIRTKI-VRNWRRKKRHLSIRKKI---YGTVERPRLCVYKSEKHIYAQIIDD---D--KGHTL VAASTL-DKEL-RETL----KKT-WNKEAAREVGKLIGKR--AIEKG-IKKVVFDRGGYRYH--GRVAELAEGAREAGLE F-------------------------------------------------------------IYE-ARAVAKYIRISPRK ARSVANSIRGKNVSEAFTILEFS---------------------------------PKKAARIIKNVLKSAVAN----A- VNNH-GLNEENLYVYTCYVNDGPRMKRLWPRGRGSADIIQKRMSHITVIVRDARKIKKGDTVKVLSGK------DK-GKT GEVVTVIPKED--KVV--VRGVNIVKRHQR----PN--AQ-MRQ-GGIIEKEAPIYVCKVA-LVCPSC-------GQ--A --TRVGFRF---LD--------DGKVR---YCKKCG---EVI--MGQKVHPRGFRLG--IT-TDWQAKWFN------E-K N--YKEYLLEDEEIRKVI--KSKYA-----QAGISEIVIERPDSE-RVVAIVKTARPGIIIGKKGAEITALRKDLEEKFI VNVEEIKT---PEVDAQLIAENVANRIEKRASYKVVMKRAIFNAMKK-GAKGIKIMVSGRLAGAEIARTEWYLKGRLPL- -QTIRSIIDYGTARAETKYGTIGIKVWVY-MWSDPIADMLTRIRNANVVFKDQVDI-PASNLKKEIAEILKREGFIKDYT YIE----D---G----KQGIIRIQMKYKGTRRNR-------E---RVIHGIVRISKPGRRIYVDKEHLPKVKNGLGIAIL TTSKGVITDKQAREIGVGGEVIAYIWMPGQKIRIRLKAYDHKLLDESAKKIVEVVKQTNAKVSGPVPLPTERTLYVVLRS PLKHKDSR-EQFEKRVHKRMIDILEPSPKTIDALMKINLPAGVDVEINLKKRLIGEVLSDKMDKTVVVAVSTLVKHPRVG KYIKRTKKYYAHDEN--NECRVGDIVEIVESRPLSKLKRWKVERIVERS------------------------------- -MGRST-KKGPFVDP-KLLKKIKQLNE---AGEKK----IIKTWSRASMIVPEMVGHTIAVYNGLKHIPVYITE-NMVGH RLGEFSFTRRFGGHA----------DK----SAS--KGQVKK >THERMO_Thermotoga_lettingae_TMO Concatenation of 2 sequences MGLRKYKPATPGVRFMIRNDFSG-LTKK------------EP-EKSLLVPLKKTGGRNHYGRITVRF-RGGGHKRQ---- YRLIDFK-R--DK-IGIPAKVSAIEYDPNRSARIALLVYA-DGEKRYILAPNGLQVGDTVLSGI-D-AE-IRVGNALPLE NIPLGTLLHNVEIRPGSGGKIARSAGVSCQLMAK--EGNYALLRMPSGELRKVHIKCYATIGVVGNEDHKNEVFGKAGRT -RWI-----GRK-P-HVRGMVMNPVDHPMGGGEGRG----KGQH-PVTP---WGMPTKGYKTR-RGRRASD-K-FIVRRR --------------------------------MKM-----ILGRKIGMTRLF--INDV---------SIPVTVVRAGPCY VVQKK----NPQ----I--DGY--CAIQVGF-------EH---VNK----------PLEGHFK----------------- ---AQ-VKPLRLLREIRL-----EDENELDSY-----EI---GQ-EIKL--D-I-FQPGEKVDITGWTKGRGFSGGIKRW GFSG-GPRAHGS-KFHRE-LGSLGQH-TEPA-KIFKGKKMPGRYGNERVTIHNLEVIKIDLENN---------------- ----------LLVLKGS-VPGARGSLVIIK-MAVVDLYN-MKGEKV-GTQELKDDIF----NI-EP-NFDVMWRYVDYQL SLRRAGTVSTKTRSE--------VS-GGGRKPW---------IQKHTGRAR--------HGS---IR-SP----IW---- RHGGVAHGPK-P-RDWSKKLPKKMKKLALKSALSQRFKEG----------------N-IIVVDDI----GFD-S------ --SKTKLFV--LPWKSEYE---NVKLSCKNIPGLK-AIIADNPGATRENESIMRIDGLNVFDILNHEK----LVLTRDMV MKIEIPLKEKYEKEV----VPKLMKEFNYRNINQVPRIEKIVINMGIG-EGSRNADLLNKHLKELAAITGQKPVITKAKK SISNFKIRKGMNVGLKVTLRGLRMWNFLYKIANIVLPKVRDFRGLNP-NSFDGHGNYSFGLTEQFVFPEIT-----PDQS PKTQGMDIVIVTT-----------------------AKTDAEAFKLLEFLGFPFMSKLG-K--KPILIPSGVQIN-I--- -E-G--D-MISVKGPKGTLSQRL--SP-Y--IKVAIEE-NK--LWV----Q-Q--NEEKMLR-TFQGTYWSLIKNMITGV TEGFEKQLEIVGVGY--RAQLQG-NK--VSLQ--LGYTHPIVLEP-P-V-GVSVEVP--A-PNVVVVKG-IDKQKVGQFA AEVRSWR------KVNVY---SGKGVKYRNEVVKLKEGK----------MIQNESYLNVADNSGAKKLRVIRVMG-FHKK Y--GTVGDIVVCSVRDVVPN-T-------GIKKGEVVKAVIVRTKKPVRRPDGTYIRFDDNAAVLID-KFNE-PRGTRVF GPVAREIR-EKGYMKIISLAPEVLTK-L--EDLRPTPGS-VKPRKRVG-RGIGSGH-GKTSGRGHKGQKSRGSGK-V--- -HMWL-E-GGQTPLHRRLPK-VG--FKSVNIRLLITPELLLEK-GFIKVK---------ILG--SGE-L-T-K-P-LIV- KAHAFSNSAKKAIEMVGGKV-K---QQR--GRM---RGEA-KGGTTVDFG----------EWGLKAL--APAWITAQQIE AGRIAIMRVM------KRSGKLWIRVFPDKPYTKKPAESRQGKGK---------GNVEGWVSVVKP-GKIIFEI--AG-- VDENTAKEALKYAASKFPIPTKI-VRKFKRIKRHLRIRKKV---FGTSERPRLSVFRSEKHIYAQIIDD---T--KGHTL VSASTL-DPDL-RARI----AKT-YNKEAAKEVGKLVAQK--ALSKG-ISQVVFDRGGFKFH--GRIRELADAAREAGLK F-------------------------------------------------------------NIE-IKAVAKFLRASPRK VRSVANTIRGKSVSEAFQVLEMS---------------------------------PKKAARLIEKVLRSAVAN----A- ENNA-NLSSDSLYISRCFVDDGPRYKRIWPRGRGRADIIQRRMCHVTVAVKS-MRVKKDDLVEVISGK------DK-GKR GKVLKVLPREN--KVV--IQGVNIVKRHQR----PI--PQ-LRE-GGIIEREAPIYASKVM-LVCPNC-------DK--P --TRVGMRF---LD--------DGKVR---FCKKCG---EIV--MGQKVHPRGFRLG--VS-ADWQTRWFN------E-K N--YATWLKEDEEIRKVV--KNAYS-----QAGISEVFIERPDNE-SVTITIKTARPGVIIGKKGAEIGKLREDLEKEVI VNVEEIKT---PETDAQLVAENIAGRIEKRASYKRAMKRALSDALRK-GATGVKVMVSGRLAGAEIARREWYLRGRLPL- -QTVRAVVDYGTATAKTKYGTIGIKVWIY-MWSDPIADMLTRIRNANVVFKEYVDV-PASNIKKAICEILKKEGFIHDYK YIE----D---G----KQGILRIHMKYKGQRRDR-------E---RVIKGIVRVSKPGRRLYVSKDEIPKVKNGIGVAIL TTSKGVVTDKEARVLGVGGEVIAYIWMPGQKIRIKLKAYDHEVLDESAKKIVEVAKSTNAKISGPIPLPTERALYVVLRS PHKHKDSR-EQFEKRVHKRLIDIIEPSPKTIDALMKINLPAGVDVEIKLKKRLTGVVVSNKMDKTVVVEVTRKLEHPVYK KYIQRSKKYYAHDEK--NECKAGDTVLIEETRPLSKMKRWRVVEVLKRE------------------------------- -MARSR-KKGPYVDP-KLLKKIRMLNE---SGEKK----IVKTWSRASTIVPEMVGHTIAVHNGLKHIPVYITE-NMVGH RLGEFAPTRRFGGHA------DKKAAT----KGQ------VR >THERMO_Thermotoga_maritima_MSB8 Concatenation of 2 sequences MGLKRFKPVTPGRRFMVISDFSD-ITKT------------EP-EKSLLAPLKKTGGRNHHGRVTVRH-RGGGHKRR---- YRIIDFK-R-YDK-AGIPAKVLAIEYDPNRSARIALLLYA-DGEKRYILAPKGVNVGDTLMSGP-D-AE-IRPGNALPLE KIPVGTLVHNVEFTPGKGGQIARAAGTYCQIMAK--EGNYALLRMPSGELRKVHIKCYATVGVVGNEDHKNEVHGKAGRV -RWL-----GRR-P-HVRGVAMNPVDHPHGGGEGRG----KGHH-PTSP---WGLPTKGYKTR-RGKRPSD-K-FIVRRR --------------------------------MKM-----IIGRKIGMTRVF--VGND---------SVPVTVIKAGPCV VVQKK----TVE----K--DGY--NAVQLGF-------EK---VNK----------PLAGHFK----------------- ---FG-VEPMKILREFRV--------ENPDEY-----EP---GQ-VIKV--D-V-FEKGEYVDVTGWTKGRGFAGAMKRW GFSG-GPKSHGS-KFHRE-LGSVGQH-TEPA-KIWKGKKMPGRYGNERVTVRNLQVVDIDPEND---------------- ----------LLVVKGG-VPGARGGLVLIR-MAQVDLLN-VKGEKV-GTLEISDFVF----NI-DP-NYDVMWRYVDMQL SNRRAGTASTKTRGE--------VS-GGGRKPW---------PQKHTGRAR--------HGS---IR-SP----IW---- RHGGVVHGPK-P-RDWSKKLNKKMKKLALRSALSVKYREN----------------K-LLVLDDL----KLE-R------ --PKTKLIV--LPWKE--EGYMNVKLSGRNLPDVK-VIIADNPNNSKNGEKAVRIDGLNVFDMLKYDY----LVLTRDMV SKIEVPLKDQYEKEI----VPALMKEFNYKNIHQVPKLVKIVINMGIG-EGSRNYDLIERHANELAKITGQKPIVTRARK SISNFKIRKGMPIGLKVTLRGARMYNFLYKLINIVLPKVRDFRGLDP-NSFDGRGNYSFGLSEQLVFPELN-----PDEV RRIQGMDITIVTT-----------------------AKTDQEARRLLELFGMPFMSRLA-K--KPIVLPQGVTVE-I--- -K-D--N-VVKVKGPKGELSQEF--LP-Y--VKIEVEG-NE--VWV----R-P--NEERKVK-MFQGTYWSLIRNMVVGV TEGYKKELEIVGIGY--RAQLQG-NT--LVMN--LGYAHPVVYEI-P-S-DVKIEVP--A-PNRIIVSG-IDKQRVGQVA AEIRAFR------PPNVY---TGKGIRYVGEVVRQKEGK----------MIQQETYLNVADNSGAKKLRVIRVIG-FHKK Y--GTVGDIVVCSVREAIPN-S-------DVKKGDVVRAVIVRTKKEIRRNDGTYIRFDDNAAVLID-KFNA-PRGTRIF GPVARELR-EKGFMKIVSLAPEVWMR-L--EDLRPTPGA-MKKRKRVG-RGPGSGH-GKTSGRGHKGQKARGSGK-V--- -HIWF-E-GGQTPLQRRLPK-RG--FKNVNVKVLVTPEKLIER-KIIKVK---------ILG--DGE-L-T-K-P-LVV- KAHAFSKSAVEKIESAGGKA-K---QQR--GRM---KGKA-KGGTFVQFG----------EWGLKAL--EPAWITAQQIE ACRIAMLRVM------KRSGKIWIRIFPDKPYTKKPPESRMGKGK---------GNVEGWVAVVKP-GKILFEV--AG-- VDEETAHEALRYAASKLPIATKI-VKKEQRLRRHRRVRKKV---FGTPERPRLCVFRSNKHIYAQIIDD---T--IGHTL VSASTL-DPEL-REKL----QKT-WNVEAAKEVGLLIGKR--ALEKG-IKKVVFDRGGYKYH--GRVKALADGAREAGLE F-------------------------------------------------------------KIE-ARAVAKYIRISPRK ARAIANTIRGKSVEEAFQILAFS---------------------------------PKKAARIMEKVLKSAVAN----A- ENNF-GLSVENLYVSECYVNDGPRMKRIWPRGRGRADIIQKRMSHITVVVRD-MRIKKGDLVEVISGK------DK-GKR GKVLRVIPKEN--KVI--VENVNMVKRHQR----PV--PQ-LRE-GGIIEREAPIYASKVM-VVCPAC-------DK--R --TRVGYRF---TE--------DGKVR---YCKKCG---EII--MGQKVHPRGFRLG--LS-ADWQAKWFN------E-K N--YKEWLLEDEEIRKII--KNKYY-----HAGISEIYVERPDAE-RINITVKTARPGIIIGRKGSEITSLREELERKVV INIEEIKT---PELDAQLVAESIASRIEKRASYKVAMKRAIMNAMRK-GAQGIKVMVAGRLGGAEIARREWYLRGRLPL- -QKIKAIIDYGTATAWTKYGTIGIKVWIY-MWSDPIADMLTRIRNANMVFKEYTDI-PASNLKKKICEILKREGFIADYK YIE----D---G----KQGILRVYLKYKGGRKNR-------E---RVIHGIVRVSHAGRRIYVDKDHIPKVKNGLGIAIL TTSKGVLTDKEARQLGVGGEVIAYVWMPGQKIRIKLKAYDHELLDESAKKIVEVAKSTNSKVSGPIPLPTERTLYCVLRS PMKHKDSR-EHFEKRVHKRLIDIIDPSPKTIDALMRINLPAGVDVEIKLRKRLTGIVVSDKMDKTVVVAVEKLVQHPLYK KYVKRTKKYHAHDER--NECKIGDVVEIEETRPLSKTKRWRVVRIIQRF------------------------------- -MGRSR-KKGPYVDR-KLLEKIRKLNE---TGEKK----VIKTWSRASMIIPEMVGHTIAVYNGMKHIPVYITE-NMIGH RLGEFAPTRRFGGHA----------DK----KAK--KGELKK >THERMO_Thermotoga_neapolitana_DSM_4359 Concatenation of 2 sequences MGLKRFKPVTPGRRFMVISDFSD-ITKT------------EP-EKSLLAPLKKTGGRNHHGRITVRH-RGGGHKRR---- YRIIDFK-R-YDK-AGIPAKVLAIEYDPNRSARIALLLYA-DGEKRYILAPKGIKVGDTLMSGS-D-AE-IKPGNALPLE KIPVGTLVHNVEFTPGKGGQIARAAGTYCQIMAK--EGDYALLRMPSGELRKVHIKCYATVGVVGNEDHKNEVHGKAGRV -RWL-----GRR-P-HVRGVAMNPVDHPHGGGEGRG----KGHH-PTSP---WGLPTKGYKTR-RGKRPSD-K-FIVRRR --------------------------------LMK---M-IIGRKIGMTRVF--IGNE---------AVPVTVIKAGPCV VVQKK----TVE----T--DGY--NAVQLGF-------EK---VNK----------PLAGHFK----------------- ---FG-VEPMRVLREFRV--------DNPDEY-----EP---GQ-VIKV--D-I-FEKGEYVDVTGWSKGRGFAGAMKRW GFSG-GPKSHGS-KFHRE-LGSVGQH-TEPA-KIWKGKKMPGRYGNERVTVRNLQVVDVDPEND---------------- ----------LIAVKGG-VPGARGGLVLIR-MAQVDLLN-VKGEKV-GTLEISDFVF----NI-DP-NYDVMWRYVDMQL SNRRAGTASTKTRGE--------VS-GGGRKPW---------PQKHTGRAR--------HGS---IR-SP----IW---- RHGGVAHGPK-P-RDWSKKLNKKMKRLALRSALSVKYREN----------------K-LLVLEDL----KLE-R------ --PKTKLIV--LPWKE--EGYVNVKLSGKNLPNVK-VIIADNPNNSKNGEKAVRIDGLNVFDMLKYDY----LILTRDMV AKIEVPLKEKYEKEI----VPALMKEFNYKNIHQVPKLVKIVVNMGIG-EGSRNYDIIERHANELAKITGQKPVVTRARK SISNFKIRKGMPIGLKVTLRKAMMYNFLYKLINIVLPKVRDFRGLDP-NSFDGRGNYSFGLSEQLVFPELS-----PDEV RRIQGMDITIVTT-----------------------AKTDQEARRLLELFGMPFMSRLA-K--KPINIPQGVTVE-V--- -N-D--G-TVKVRGPKGELTQDF--LP-Y--VKIEIED-GK--VWI----R-P--NEARKVK-MFQGTYWSLIRNMVIGV TEGYKKELEIVGIGY--RAQLQG-NT--LVMN--LGYAHPVVYEI-P-S-DVKVEVP--A-PNRIVVSG-IDKQRVGQVA AEIRAFR------PPNVY---TGKGIRYVGEVVRQKEGK----------MIQQETYLNVADNSGAKKLRVIRVLG-FHKK Y--GTVGDIVVCSVRDAIPN-S-------DVKKGDVVRAVIVRTKKEIRRSDGTYIRFDDNAAVLID-KFNA-PRGTRIF GPVARELR-EKGFMKIVSLAPEVWMR-L--EDLRPTPGS-MKKRKRVG-RGPGSGH-GKTSGRGHKGQKARGTGK-V--- -HPWF-E-GGQTPLQRRLPK-RG--FKNVNVKVLVTPAKLLER-KIVKIK---------ILG--DGE-L-T-K-P-LIV- KAHAFSKSALEKIESVGGKA-K---QQR--GRM---KGKA-KGGTLVQFG----------EWGLKAL--EPAWITAQQIE ACRIAMMRVM------KRAGKIWIRIFPDKPYTKKPAESRMGKGK---------GNVEGWVAVVKP-GKILFEI--AG-- VDEETAHEALRYAASKLPIATKV-VRNERRIRRHRRVRKKV---FGTPERPRLCVFRSNKHIYAQIIDD---T--IGHTL VSASTL-DPEL-REKL----QKT-WNIEAAKEVGLLIGKR--AIEKG-IKKVVFDRGGYKYH--GRVKALADGAREAGLE F-------------------------------------------------------------KIE-ARAVAKYIRISPRK ARAVANTIRGKSVEEAFRILAFS---------------------------------PKKAARIIEKVLRSAVAN----A- ENNF-GLDAANLYVAECYVNDGPRLKRIWPRGRGRADIIKKRMSHITVVVRDRMRIKKGDLVEVISGK------DK-GKR GKVLRVLPKED--KVI--VEGVNMVKRHQR----PI--PQ-LRE-GGIIEREAPIYACKVM-VVCPAC-------DK--R --TRVGYRF---TE--------DGKVR---YCKKCG---EII--MGQKVHPRGFRLG--LS-ADWQAKWFN------E-K N--YKEWLLEDEEIRKII--KNKYY-----HAGISEIYIERPDAE-RVNITVKTARPGIIIGRKGAEITSLREELEKRMV INIEEIKT---PELDAQLVAESIASRIEKRASYKVAMKRAIMNAMRK-GAQGIKVMVAGRLGGAEIARREWYLRGRLPL- -QKIKAIIDYGTAVAWTKYGTIGVKVWIY-MWSDPIADMLTRIRNANMVFKEYTDI-PASNLKRKICEILKREGFIADYK YIE----D---G----KQGILRVYLKYKGGRKNR-------E---RVIHGIVRVSHAGRRVYVDKDHIPKVKNGLGIAIL TTSKGVLTDKEARQLGVGGEVIAYVWMPGQRIRIKLKAYDHELLDESAKKIVEVAKSTNSKVSGPIPLPTERTLYCVLRS PMKHKDSR-EHFEKRVHKRLIDIIDPSPKTIDALMRINLPAGVDVEIKLRKRMIGVVVSDKMDKTVVVAVERHVQHPLYK KYIKRTKKYHAHDEK--NECRVGDVVEIEETRPLSKTKRWRVVKIIKRF------------------------------- -MGRSK-KKGPYVDR-KLLEKIRKLNE---TGEKK----VIKTWSRASMIIPEMVGHTIAVYNGMKHIPVYITE-NMIGH RLGEFAPTRRFGGHA----------DK----KAK--KGELKK >THERMO_Thermotoga_petrophila_RKU-1 Concatenation of 2 sequences MGLKRFKPVTPGRRFMVISDFSD-ITKT------------EP-EKSLLAPLKKTGGRNHHGRVTVRH-RGGGHKRR---- YRIIDFK-R-YDK-AGIPAKVLAIEYDPNRSARIALLLYA-DGEKRYILAPKGVNVGDTLMSGP-D-AE-IRPGNALPLE KIPVGTLVHNVEFTPGKGGQIARAAGTYCQIMAK--EGNYALLRMPSGELRKVHIKCYATVGVVGNEDHKNEVHGKAGRV -RWL-----GRR-P-HVRGVAMNPVDHPHGGGEGRG----KGHH-PTSP---WGLPTKGYKTR-RGKRPSD-K-FIVRRR --------------------------------MKM-----IIGRKIGMTRVF--VGND---------SVPVTVIKAGPCV VVQKK----TVE----K--DGY--NAVQLGF-------EK---VNK----------PLAGHFK----------------- ---FG-VEPMKILREFRV--------ENPDEY-----EP---GQ-VIKV--D-V-FEKGEYVDVTGWTKGRGFAGAMKRW GFSG-GPKSHGS-KFHRE-LGSVGQH-TEPA-KIWKGKKMPGRYGNERVTVRNLQVVDIDPEND---------------- ----------LLVVKGG-VPGARGGLVLIR-MAQVDLLN-VKGEKV-GTLEISDFVF----NI-DP-NYDVMWRYVDMQL SNRRAGTASTKTRGE--------VS-GGGRKPW---------PQKHTGRAR--------HGS---IR-SP----IW---- RHGGIAHGPK-P-RDWSKKLNKKMKKLALRSALSVKYREN----------------K-LFVLDDL----KLE-R------ --PKTKLIV--LPWKD--EGYMNVKLSGKNLPNVK-VIIADNPNNSKNGEKAVRIDGLNVFDMLKYDY----LVLTQDMV SKIEVPLKDQYEKEI----VPALMKEFNYKNIHQVPKLVKIVINMGIG-EGSRNYDLIERHANELAKITGQKPIVTRARK SISNFKIRKGMPIGLKVTLRGARMYNFLYKLINIVLPKVRDFRGLDP-NSFDGRGNYSFGLSEQLVFPELS-----PDEV RRIQGMDITIVTT-----------------------AKTDQEARRLLELFGMPFMSRLA-K--KPIVLPQGVTVE-I--- -K-D--N-VVKVKGPKGELSQEF--LP-Y--VKIEVEG-NE--VWV----R-P--NENRKIK-MFQGTYWSLIRNMVVGV TEGYKKELEIVGIGY--RAQLQG-NT--VVMN--LGYAHPVVYEI-P-S-DVKIEVP--A-PNRIVVSG-IDKQRVGQVA AEIRAFR------PPNVY---TGKGIRYVGEVVRQKEGK----------MIQQETYLNVADNSGAKKLRVIRVIG-FHKK Y--GTVGDIVVCSVREAIPN-S-------DVKKGDVVRAVIVRTKKEIRRSDGTYIRFDDNAAVLID-KFNA-PRGTRIF GPVARELR-EKGFMKIVSLAPEVWMR-L--EDLRPTPGA-MKKRKRVG-RGPGSGH-GKTSGRGHKGQKARGSGK-V--- -HIWF-E-GGQTPLHRRLPK-RG--FNNVNVKVLVTPEKLIER-KIIKIK---------ILG--DGE-L-T-K-P-LVV- KAHAFSKSAVEKIESAGGKA-K---QQR--GRM---KGKA-KGGTFVQFG----------EWGLKAL--EPAWITAQQIE ACRIAMLRAM------KRSGKIWIRIFPDKPYTKKPPESRMGKGK---------GNVEGWVAVVKP-GKILFEV--AG-- VDEETAHEALRYAASKLPIATKV-VKKEQRLRRHRRVRKKV---FGTPERPRLCVFRSNKHIYAQIIDD---T--IGHTL VSASTL-DPEL-REKL----QKT-WNVEAAKEVGLLIGKR--ALEKG-IKKVVFDRGGYKYH--GRVKALADGAREAGLE F-------------------------------------------------------------KIE-AKAVARYIRISPRK ARAIANTIRGKSVEEAFQILAFS---------------------------------PKKAARIMEKVLKSAVAN----A- ENNF-GLSVENLYVSECYVNDGPRMKRIWPRGRGRADIIQKRMSHITIVVRD-MRIKKGDLVEVISGK------DK-GKR GKVLRVIPKEN--KVI--VENVNMVKRHQR----PI--PQ-LRE-GGIIEREAPIYASKVM-VVCPAC-------DK--R --TRVGYRF---TE--------DGKVR---YCKKCG---EII--MGQKVHPRGFRLG--LS-ADWQAKWFN------E-K N--YKEWLLEDEEIRKFI--KNRYY-----HAGISEIYVERPDAE-RINITVKTARPGIIIGRKGAEITSLREELERKVV INIEEIKT---PELDAQLVAESIASRIEKRASYKVAMKRAIMNAMRK-GAQGIKVMVAGRLGGAEIARREWYLRGRLPL- -QKLKAIIDYGTATAWTKYGTIGIKVWIY-MWSDPIADMLTRIRNANMVFKEYTDI-PASNLKKKICEILKREGFIADYK YIE----D---G----KQGILRVYLKYKGGRKNR-------E---RVIHGIVRVSHSGRRIYVDKDHIPKVKNGLGIAIL TTSKGVLTDKEARQLGVGGEVIAYVWMPGQKIRIKLKAYDHELLDESAKKIVEVAKSTNSKVSGPIPLPTERTLYCVLRS PMKHKDSR-EHFEKRVHKRLIDIIDPSPKTIDALMRINLPAGVDVEIKLRKRLTGIVVSDKMDKTVVVAVEKLVQHPIYK KYVKRTKKYHAHDER--NECKIGDVVEIEETRPLSKTKRWRVVRIIQRF------------------------------- -MGRSS-KKGPYVDK-KLLEKIRKLNE---TGEKK----VIKTWSRASMIIPEMVGHTIAVYNGMKHIPVYITE-NMIGH RLGEFAPTRRFGGHA----------DK----KAK--KGELKK >THERMO_Thermotoga_sp_RQ2 Concatenation of 2 sequences MGLKRFKPVTPGRRFMVISDFSD-ITKT------------EP-EKSLLAPLKKTGGRNHHGRVTVRH-RGGGHKRR---- YRIIDFK-RY-DK-AGIPAKVLAIEYDPNRSARIALLLYA-DGEKRYILAPKGVNVGDTLMSGP-D-AE-IRPGNALPLE KIPVGTLVHNVEFTPGKGGQIARAAGTYCQIMAK--EGNYALLRMPSGELRKVHIKCYATVGVVGNEDHKNEVHGKAGRV -RWL-----GRR-P-HVRGVAMNPVDHPHGGGEGRG----KGHH-PTSP---WGLPTKGYKTR-RGKRPSD-K-FIVRRR --------------------------------MKM-----IIGRKIGMTRVF--VGND---------SVPVTVIKAGPCV VVQKK----TVE----K--DGY--NAVQLGF-------EK---VNK----------PLAGHFK----------------- ---FG-VEPMKILREFRV--------ENPDEY-----EP---GQ-VIKV--D-V-FEKGEYVDVTGWTKGRGFAGAMKRW GFSG-GPKSHGS-KFHRE-LGSVGQH-TEPA-KIWKGKKMPGRYGNERVTVRNLQVVDIDPEND---------------- ----------LLVVKGG-VPGARGGLVLIR-MAQVDLLN-VKGEKV-GTLEISDFVF----NI-DP-NYDVMWRYVDMQL SNRRAGTASTKTRGE--------VS-GGGRKPW---------PQKHTGRAR--------HGS---IR-SP----IW---- RHGGIAHGPK-P-RDWSKKLNKKMKKLALRSALSVKYREN----------------K-LFVLDDL----KLE-R------ --PKTKLIV--LPWKD--EGYMNVKLSGKNLPNVK-VIIADNPNNSKNGEKAVRIDGLNVFDMLKYDY----LVLTQDMV SKIEVPLKDQYEKEI----VPALMKEFNYKNIHQVPKLVKIVINMGIG-EGSRNYDLIERHANELAKITGQKPIVTRARK SISNFKIRKGMPIGLKVTLRGARMYNFLYKLINIVLPKVRDFRGLDP-NSFDGRGNYSFGLSEQLVFPELS-----PDEV RRIQGMDITIVTT-----------------------AKTDQEARRLLELFGMPFMSRLA-K--KPIVLPQGVTVE-I--- -K-D--N-VVKVKGPKGELSQEF--LP-Y--VKIEVEG-NE--VWV----R-P--NENRKIK-MFQGTYWSLIRNMVVGV TEGYKKELEIVGIGY--RAQLQG-NT--VVMN--LGYAHPVVYEI-P-S-DVKIEVP--A-PNRIVVSG-IDKQRVGQVA AEIRAFR------PPNVY---TGKGIRYVGEVVRQKEGK----------MIQQETYLNVADNSGAKKLRVIRVIG-FHKK Y--GTVGDIVVCSVREAIPN-S-------DVKKGDVVRAVIVRTKKEIRRSDGTYIRFDDNAAVLID-KFNA-PRGTRIF GPVARELR-EKGFMKIVSLAPEVWMR-L--EDLRPTPGA-MKKRKRVG-RGPGSGH-GKTSGRGHKGQKARGSGK-V--- -HIWF-E-GGQTPLHRRLPK-RG--FNNVNVKVLVTPEKLIER-KIIKIK---------ILG--DGE-L-T-K-P-LVV- KAHAFSKSAVEKIESAGGKA-K---QQR--GRM---KGKA-KGGTFVQFG----------EWGLKAL--EPAWITAQQIE ACRIAMLRAM------KRSGKIWIRIFPDKPYTKKPPESRMGKGK---------GNVEGWVAVVKP-GKILFEV--AG-- VDEETAHEALRYAASKLPIATKV-VKKEQRLRRHRRVRKKV---FGTPERPRLCVFRSNKHIYAQIIDD---T--IGHTL VSASTL-DPEL-REKL----QKT-WNVEAAKEVGLLIGKR--ALEKG-IKKVVFDRGGYKYH--GRVKALADGAREAGLE F-------------------------------------------------------------KIE-AKAVARYIRISPRK ARAIANTIRGKSVEEAFQILAFS---------------------------------PKKAARIMEKVLKSAVAN----A- ENNF-GLSVENLYVSECYVNDGPRMKRIWPRGRGRADIIQKRMSHITVVVRD-MRIKKGDLVEVISGK------DK-GKR GKVLRVIPKEN--KVI--VENVNMVKRHQR----PI--PQ-LRE-GGIIEREAPIYASKVM-VVCPAC-------DK--R --TRVGYRF---TE--------DGKVR---YCKKCG---EII--MGQKVHPRGFRLG--LS-ADWQAKWFN------E-K N--YKEWLLEDEEIRKFI--KNKYY-----HAGISEIYVERPDAE-RINITVKTARPGIIIGRKGAEITSLREELERKVV INIEEIKT---PELDAQLVAESIASRIEKRASYKVAMKRAIMNAMRK-GAQGIKVMVAGRLGGAEIARREWYLRGRLPL- -QKLKAIIDYGTATAWTKYGTIGIKVWIY-MWSDPIADMLTRIRNANMVFKEYTDI-PASNLKKKICEILKREGFIADYK YIE----D---G----KQGILRVYLKYKGGRKNR-------E---RVIHGIVRVSHSGRRIYVDKDHIPKVKNGLGIAIL TTSKGVLTDKEARQLGVGGEVIAYVWMPGQKIRIKLKAYDHELLDESAKKIVEVAKSTNSKVSGPIPLPTERTLYCVLRS PMKHKDSR-EHFEKRVHKRLIDIIDPSPKTIDALMRINLPAGVDVEIKLRKRLTGIVVSDKMDKTVVVAVEKLVQHTIYK KYVKRTKKYHAHDER--NECKIGDVVEIEETRPLSKTKRWRVVRIIQRF------------------------------- -MGRSS-KKGPYVDK-KLLEKIRKLNE---TGEKK----VIKTWSRASMIIPEMVGHTIAVYNGMKHIPVYITE-NMIGH RLGEFAPTRRFGGHA----------DK----KAK--KGELKK