Phosphorylation Regulates FOXC2-Mediated Transcription in Lymphatic Endothelial Cells

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Fig. S1 (FOXC2 phosphorylation), S2 (Serine phosphorylation sites), S3 (T247 and S251 phosphorylation sites), S4 (FOXC2 phosphorylation sites), S5 (Immunoblot analysis of Myc-FOXC2 and Myc-pmFOXC2), S6 (Hierarchical cluster analysis), S7 (Effects of loss of phosphorylation), S8 (Dephosphorylation with γ-PPase and binding of Myc-FOXC2), S9 (Loss of FOXC2 phosphorylation and expression of FOXC2 target genes), S10 (FOXC2 overexpression and vascular remodeling), and S11 (Blood-filled lymphatic vessels in FOXC2 embryos) and Tables S1 and S2 (Tryptic [S1] and Glu-C [S2] peptides), and S3 (Gene expression signature)

  PDF, 8.0M

• Supplemental file 2 -

  Data set SA1 (Physiological FOXC2 binding sites regulated by phosphorylation in LECs)

  XLS, 87K