Fig. 6. Association and dissociation of integrin αv/β3 tails. 2D NOESY spectra of av tail in the absence (black) and presence (red) of maltose-binding protein (MBP)-b3 (αv:MBP-β3 = 1mM:0.1mM), showing substantial transferred nucleear Overhauser effects (NOEs) due to αv/β3 tail association. Addition of talin-H (0.2mM, blue) or talin F2-F3 (0.2 mM, green) abolished the transferred NOEs.