Analyte

Normal range

Preleptin

2 months leptin

18 months leptin

P value

IGF-I

120–400

141 ± 14

137 ± 15

154 ± 16

N.S.

IGF-II

290–730

484 ± 17

480 ± 16

487 ± 17

N.S.

IGFBP-1 (fasting)

13–120

21.1 ± 1.3

30.8 ± 7.1

140 ± 42

0.02

IGFBP-1 (postprandial)

10–30

3.7 ± 0.5

8.6 ± 1.9

18.1 ± 2.6

0.0001

IGFBP-2

360–1020

528 ± 54

571 ± 32

936 ± 53

0.0001

IGFBP-3

1500–3600

1606 ± 96

1588 ± 78

1633 ± 82

N.S.

IGFBP-6

100–340

299 ± 12

288 ± 10

282 ± 12

N.S.