Fig. 8. Electroretinograms (ERGs) of wild-type larvae and noa mutants at 7 days postfertilization (dpf). ERGs were performed as described (1). Larvae were dark adapted for a minimum of 2 h and then positioned for recordings under dim red light. noa mutants (B) display an abnormal ERG in comparison to wild-type larvae (A). With increasing white background light intensities noa shows a decreased ability to adapt to background light in comparison to wild-type siblings. Flash intensity of 7.8 mJ/cm² white light was given at time 0 in the presence or absence of white background light. Initial adaptation studies were previously presented (2). Adaptation data is summarized in Table 1. (Scale bar is 200 m V.)

1. Van Epps, H. A., Yim, C. M., Hurley, J. B. & Brockerhoff, S. E. (2001) Invest. Ophthalmol. Vis. Sci. 42, 868-874.

2. Brockerhoff, S. E., Dowling, J. E. & Hurley, J. B. (1998) Vision Res. 38, 1335-1339.