Human Immunodeficiency Virus Protease Inhibitors Interact with ATP Binding Cassette Transporter 4/Multidrug Resistance Protein 4: A Basis for Unanticipated Enhanced Cytotoxicity

Files in this Data Supplement:

• Supplemental Data -

  Methods

  Supplementary Table S1 - Input details for pharmacophore construction

  Supplementary Table S2 - Training set for diverse MRP4 models

  Supplementary Table S3 - MRP4 model 1

  Supplementary Table S4 - MRP4 model 2

  Supplemental Figure 1 - Structures of HIV protease inhibitors used in the study

  Supplemental Figure 2 - Inhibitor pharmacophores for MRP4

  Supplemental Figure 3 - Ritonavir is a weak MRP4 inhibitor and substrate