[Posted as supplied by author.]
Proportions of subjects with each outcome according to confounding variables considered in the multivariable analyses.
Variable | Asthma at 69-81 months | Wheeze and whistling at 69-81 months | Doctor diagnosed asthma at 91 months | Atopy |
Maternal education | ||||
< O level | 13.1 (291) | 10.7 (203) | 22.3 (399) | 18.2 (248) |
O level | 12.6 (360) | 9.3 (263) | 20.6 (561) | 21.2 (465) |
> O level | 10.5 (341) | 9.5 (305) | 18.5 (581) | 21.0 (559) |
P value | <0.0001 | 0.3 | 0.004 | 0.07 |
Ethnicity | ||||
White | 12.2 (927) | 9.6 (720) | 19.9 (1439) | 19.9 (1171) |
Non-white | 14.1 (43) | 11.0 (33) | 23.5 (68) | 30.2 (76) |
P value | 0.3 | 0.4 | 0.1 | 0.0002 |
Number of 0-15 year olds in household | ||||
1 | 12.0 (406) | 9.5 (319) | 20.0 (649) | 22.2 (566) |
2 | 12.2 (359) | 9.9 (287) | 19.7 (550) | 20.1 (459) |
>=3 | 12.9 (181) | 10.0 (138) | 20.6 (269) | 17.9 (191) |
P value | 0.7 | 0.8 | 0.8 | 0.009 |
Sex of child | ||||
Male | 13.9 (591) | 11.0 (460) | 22.9 (928) | 23.9 (777) |
Female | 10.9 (433) | 8.6 (338) | 17.5 (669) | 17.0 (547) |
P value | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
Duration of breast feeding | ||||
Never | 14.3 (239) | 10.9 (179) | 22.3 (353) | 18.1 (203) |
<1 month | 12.6 (154) | 9.3 (112) | 21.4 (249) | 19.2 (172) |
1-3 months | 13.9 (169) | 10.1 (121) | 21.3 (245) | 19.7 (184) |
3-6 months | 10.6 (111) | 8.5 (88) | 17.9 (179) | 21.8 (183) |
>6 months | 10.6 (273) | 9.5 (241) | 18.2 (447) | 21.7 (461) |
P value | 0.001 | 0.3 | 0.003 | 0.1 |
Environmental tobacco smoke at 6 months | ||||
Yes | 13.9 (352) | 10.8 (271) | 22.6 (534) | 18.1 (333) |
No | 11.5 (620) | 9.2 (489) | 19.0 (981) | 21.6 (907) |
P value | 0.003 | 0.03 | 0.0004 | 0.002 |
Maternal smoking during pregnancy | ||||
None | 12.0 (795) | 9.4 (614) | 19.4 (1231) | 21.3 (1108) |
1-9 per day | 12.7 (66) | 9.7 (49) | 23.8 (119) | 15.5 (59) |
10-19 per day | 16.9 (92) | 13.2 (71) | 25.6 (128) | 16.3 (61) |
³ 20 per day | 11.0 (19) | 12.9 (22) | 20.4 (31) | 15.6 (20) |
P value | 0.01 | 0.03 | 0.002 | 0.003 |
Maternal age | ||||
<20 years | 19.1 (35) | 12.5 (22) | 28.6 (50) | 14.5 (17) |
20-24 years | 14.0 (161) | 11.2 (128) | 24.6 (268) | 17.6 (156) |
³ 25 years | 12.0 (828) | 9.5 (648) | 19.4 (1279) | 21.1 (1151) |
P value | 0.003 | 0.1 | <0.0001 | 0.02 |
Crowding in home (persons/room)* | ||||
<0.5 | 11.6 (179) | 9.2 (141) | 19.9 (292) | 23.2 (269) |
0.5 - <0.75 | 11.6 (341) | 9.4 (272) | 19.1 (533) | 21.2 (480) |
0.75 - <1 | 11.7 (142) | 8.3 (99) | 18.4 (212) | 19.1 (182) |
1 or more | 14.5 (239) | 11.3 (184) | 23.2 (357) | 18.8 (220) |
P value | 0.02 | 0.05 | 0.004 | 0.03 |
Damp housing | ||||
Yes | 13.0 (496) | 10.5 (391) | 20.4 (733) | 20.9 (613) |
No | 11.4 (458) | 9.0 (355) | 19.4 (743) | 20.2 (609) |
P value | 0.03 | 0.03 | 0.3 | 0.5 |
Household cats | ||||
Yes | 11.2 (253) | 9.5 (210) | 19.4 (420) | 18.0 (316) |
No | 12.6 (702) | 9.8 (538) | 20.2 (1061) | 21.7 (910) |
P value | 0.1 | 0.7 | 0.5 | 0.001 |
Birth weight | ||||
£ 2500 g | 15.8 (74) | 12.5 (58) | 23.6 (106) | 18.6 (71) |
2501-3000 g | 13.5 (159) | 11.2 (129) | 21.2 (243) | 20.6 (191) |
>3000 g | 12.0 (791) | 9.4 (611) | 19.9 (1248) | 20.6 (1062) |
P value | 0.03 | 0.02 | 0.1 | 0.7 |
Preterm delivery | ||||
<37 weeks | 15.1 (66) | 12.1 (52) | 22.5 (95) | 18.0 (65) |
³ 37 weeks | 12.3 (958) | 9.7 (746) | 20.2 (1502) | 20.6 (1259) |
P value | 0.09 | 0.1 | 0.3 | 0.3 |
Maternal asthma/eczema | ||||
No | 10.7 (589) | 8.0 (438) | 17.6 (929) | 18.9 (800) |
Yes | 16.5 (391) | 13.9 (325) | 26.1 (591) | 24.3 (460) |
P value | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
*Crowding in home calculated as number of residents/total number of rooms (excluding kitchen and bathroom)