Increased Sequence Coverage through Combined Targeting of Variant and Conserved Epitopes Correlates with Control of HIV Replication

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Table S1 (Peptides and variants tested.)

  Table S2 (Example of data analysis.)

  Fig. S1 (No significant differences in response magnitude between controllers and progressors.)

  Fig. S2 (Controllers and progressors similarly targeted conserved epitopes.)

  Fig. S3 (Epitope variant recognition is extensive both within and between individuals.)

  Fig. S4 (Overall variant recognition is similar between individuals with and without B*27 and B*57 alleles.)

  Fig. S5 (Functionality changes upon variant recognition.)

  Fig. S6 (Response magnitude is associated with epitope variant recognition.)

  Fig. S7 (Sequence coverage for all epitopic regions targeted by controllers and progressors.)

  Fig. S8 (Recognition of founder viruses by controllers and progressors.)

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