Brown adipose tissue dynamics in wild-type and UCP1-knockout mice: in vivo insights with magnetic resonance

Supplemental Data

Files in this Data Supplement:

  • Supplemental figure I - Transmit/receive surface loop coil for 31P-spectroscopy in brown adipose tissue of mice.
  • Supplemental figure II - Association between iBAT wet weight and iBAT volume of UCP1-KO and WT mice acclimated to 5°C ambient temperature.
  • Supplemental figure III - Response of oxygen consumption (VO2), heart rate, respiration rate and respiratory quotient (RQ) to noradrenaline injection (NA).
  • Supplemental video I - Vascularization of the interscapular brown adipose tissue. The angiography was acquired with a time of flight 2D sequence in a WT mouse acclimated to 30°C (repetition time: 35 ms, echo time: 5.04 ms, FoV: 30 x 30 mm2, matrix: 512 x 512, slices: 28, slice thickness: 0.3 mm, voxel size: 0.059 x 0.059 x 0.3 mm3, acquisition time: 406 s). Best results for watching the video are obtained with Windows Mediaplayer or VLC Mediaplayer.
  • Supplemental video I - Vascularization of the interscapular brown adipose tissue. The angiography was acquired with a time of flight 2D sequence in a WT mouse acclimated to 30°C (repetition time: 35 ms, echo time: 5.04 ms, FoV: 30 x 30 mm2, matrix: 512 x 512, slices: 28, slice thickness: 0.3 mm, voxel size: 0.059 x 0.059 x 0.3 mm3, acquisition time: 406 s). Best results for watching the video are obtained with Windows Mediaplayer or VLC Mediaplayer.