CLUSTAL Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 -----------------MSQHYGKNVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISG Salmonella_3197/1-913 MTSLKLVPVPPVAQLEGVSQHYGKTAALNNITLDIPARSMVGLIGPDGVGKSSLLSLISG Escherichia_3284/1-911 MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISG Salmonella_1825/1-491 MSSLQI--------SQG-TFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAG Shigella_660/1-490 MSSLQI--------LQG-TFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAG Escherichia_694/1-490 MSSLQI--------LQG-TFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAG Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 ARVIEQGNVMVLGGDMRD-PRHRRDVCPRIAWMPQGLGKNLYHTLSVYE-NVDFFARLFG Salmonella_3197/1-913 ARVIEQGNVIVLGGDMRD-AKHRRDVCPRIAWMPQGLGKNLYHTLSVYE-NVDFFARLFG Escherichia_3284/1-911 ARVIEQGNVMVLGGDMRD-PKHRRDVCPRIAWMPQGLGKNLYHTLSVYE-NVDFFARLFG Salmonella_1825/1-491 ELPLLTGERQCRFTRITRLSFEQLQKLVSDEWQRNN-----TDMLSPGEDDTGRTTAEII Shigella_660/1-490 ELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNN-----TDMLGPGEDDTGRTTAEII Escherichia_694/1-490 ELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNN-----TDMLGPGEDDTGRTTAEII Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 HDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGV Salmonella_3197/1-913 HDKAEREARITELLNSTGLAPFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGV Escherichia_3284/1-911 HDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGV Salmonella_1825/1-491 QDEVHHPARCAMLAQQFGISALLDRRFKYLSTGETRKALLCQALMSEPELLILDEPFDGL Shigella_660/1-490 QDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDESFDGL Escherichia_694/1-490 QDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGL Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 DPLSRSQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQ Salmonella_3197/1-913 DPLSRAQFWDLIDSIRQRQTNMSVLVATAYMEEAERFDWLVAMNAGEILATGSAQQLRAK Escherichia_3284/1-911 DPLSRSQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQ Salmonella_1825/1-491 DVAARHQLAQRLTALNQAGITLALV-LNRFDEIPDFVQFAGVLANCTLAETGTTAELLQR Shigella_660/1-490 DVASRQQLAERLASLHQSGITLVLV-LNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQ Escherichia_694/1-490 DVASRQQLAERLASLHQSGITLVLV-LNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQ Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 TQSATLEEAFINLLPQAQRQAHQAVVIPPYQPE-------NAEIAIEARDLTMRFGSFVA Salmonella_3197/1-913 NHSATLEQAFIALLPEAQRQAHKPVVIPPYHAE-------QEEIAIEAKDLTMRFGKFVA Escherichia_3284/1-911 TQSATLEEAFINLLPQAQRQAHQAVVIPPYQPE-------NAEIAIEARDLTMRFGSFVA Salmonella_1825/1-491 A--------LVAQLAHSERLAD--VQLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPI Shigella_660/1-490 A--------LVAQLAHSEQLEG--VQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPI Escherichia_694/1-490 A--------LVAQLAHSEQLEG--VQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPI Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 VDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGE-AWLFGQPVDP--KDIDTR Salmonella_3197/1-913 VDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGQ-AWLFGQPVDP--NDIDTR Escherichia_3284/1-911 VDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGE-AWLFGQPVDP--KDIDTR Salmonella_1825/1-491 LHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIK Shigella_660/1-490 LNNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDIK Escherichia_694/1-490 LNNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDIK Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 RRVGYMSQAFSLYNELTVR-QNLELHARLFH-IPEA-EIPARVAEMSERF----KLN-DV Salmonella_3197/1-913 RRVGYMSQAFSLYNELTVR-QNLELHARLFH-IPPA-EIPARVAQMIERF----MLT-EV Escherichia_3284/1-911 RRVGYMSQAFSLYNELTVR-QNLELHARLFH-IPEA-EIPARVAEMSERF----KLN-DV Salmonella_1825/1-491 KHIGYVSSSLHLDYRVSTTVRNVILS-GYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRT Shigella_660/1-490 KHIGYVSSSLHLDYRVSTTVRNVILS-GYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRT Escherichia_694/1-490 KHIGYVSSSLHLDYRVSTTVRNVILS-GYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRT Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 EDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLMVDLSRQDKVT Salmonella_3197/1-913 EDTLPASLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLMVDLSRQDKVT Escherichia_3284/1-911 EDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLMVDLSRQDKVT Salmonella_1825/1-491 ADAPFHSLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQ Shigella_660/1-490 ADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQ Escherichia_694/1-490 ADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQ Escherichia_3283/1-374 ------------------------------------------------------------ Salmonella_1792/1-368 ------------------------------------------------------------ Yersinia_2704/1-368 ------------------------------------------------------------ Escherichia_726/1-368 ------------------------------------------------------------ Shigella_3463/1-375 ------------------------------------------------------------ Shigella_717/1-368 ------------------------------------------------------------ Salmonella_3196/1-374 ------------------------------------------------------------ Shigella_3464/1-894 IFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFIAYLQEAAGQSNE Salmonella_3197/1-913 IFISTHFMNEAERCDRMSLMHAGKVLASGTPQELVQQRGAANLEAAFISWLQEAAGAAPE Escherichia_3284/1-911 IFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFIAYLQEAAGQSNE Salmonella_1825/1-491 LLFVSHHAEDAPTCITHRLEF----VPEGERYKYVSGRCNN------------------- Shigella_660/1-490 LLFVSHHAEDAPACITHRLEF----VPDGGLYRYVLTKIY-------------------- Escherichia_694/1-490 LLFVSHHAEDAPACITHRLEF----VPDGGLYRYVLTKIY-------------------- Escherichia_3283/1-374 ------------------MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATV Salmonella_1792/1-368 --------------------MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFA Yersinia_2704/1-368 --------------------MFHRLYTLIIKELQSLLREPQTRAILIMPVILQVILFPFA Escherichia_726/1-368 --------------------MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFA Shigella_3463/1-375 -----------------MMRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATV Shigella_717/1-368 --------------------MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFA Salmonella_3196/1-374 ------------------MRGLRNIYNLGVKELRSLLGDKAMLALIVFAFTISVYSSATV Shigella_3464/1-894 AEAPPVVHD--TTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALMGTVILMLIMGYG Salmonella_3197/1-913 TPIPPSQTPAASGKPSRQGLSFRRLFSYSRREALELRRDPVRSTLALLRTVILMLIMGYG Escherichia_3284/1-911 AEAPPVVHD--TTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALMGTVILMLIMGYG Salmonella_1825/1-491 ------------------------------------------------------------ Shigella_660/1-490 ------------------------------------------------------------ Escherichia_694/1-490 ------------------------------------------------------------ Escherichia_3283/1-374 TPGSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPP--EMITADEMDAGLDAGRYTFAIN Salmonella_1792/1-368 ATLEVTNATIAIYNEDNGKHSVELTQRFARAKAFTHVLLLNSPQEIQPTIDTQKALLLVR Yersinia_2704/1-368 ATLEVTNATIAIYSEDSGKASVELTQRFAKAEAFSHVLLLHSPQEIQPVIDNQKALLLIR Escherichia_726/1-368 ATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVR Shigella_3463/1-375 TPGSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPP--EMITADEMDAGLDAGRYTFAIN Shigella_717/1-368 ATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVR Salmonella_3196/1-374 LPGSLHLAPIAIADMDQSQLSNRIVNSFYRPWFLPP--EMITATEMDAGLDAGRYTFAVN Shigella_3464/1-894 ISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDELDRRMRAGDITVAIE Salmonella_3197/1-913 ISMDVENLRFAVLDRDQTVSSQAWSLNLAGSRYFIEQPPLASYDELDRRMRSGELAVAIE Escherichia_3284/1-911 ISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDELDRRMRAGDITVAIE Salmonella_1825/1-491 ------------------------------------------------------------ Shigella_660/1-490 ------------------------------------------------------------ Escherichia_694/1-490 ------------------------------------------------------------ Escherichia_3283/1-374 IPPNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNS--EPL Salmonella_1792/1-368 FPADFSRNLDTFQPAPMQLILDGRNSNSAQIAANYLQQIVKEYQQTLMDGKP--K--PNN Yersinia_2704/1-368 FPEQFSADLANGKMTQLQLVLDGRNSNSAQIAANYIQQIVQEYQLELTKGQV--K--PNN Escherichia_726/1-368 FPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKP--K--PNN Shigella_3463/1-375 IPPNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNS--EPL Shigella_717/1-368 FPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKP--K--PNN Salmonella_3196/1-374 IPPNFQRDVLAGRQPDIQVNVDATRMSQAFTGNSYIQNIISGEVNSFVARARGDN--VQP Shigella_3464/1-894 IPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWLQDVASRQSTPASQSGL Salmonella_3197/1-913 IPPNFGRDIARGTPAQIGVWVDGAMPSRAETVKGYVQAMHQSWLQEAASRQPNPVKQIGL Escherichia_3284/1-911 IPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWLQDVASRQSTPASQSGL Salmonella_1825/1-491 ------------------------------------------------------------ Shigella_660/1-490 ------------------------------------------------------------ Escherichia_694/1-490 ------------------------------------------------------------ Escherichia_3283/1-374 VSLETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF Salmonella_1792/1-368 SELVVRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTW Yersinia_2704/1-368 SELVIRNWYNPNLDYKWFVVPSLIAMITTIGVLIVTSLSVAREREQGTLEQLLVSPLTTW Escherichia_726/1-368 SELVVRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTW Shigella_3463/1-375 VSLETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF Shigella_717/1-368 SELVVRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTW Salmonella_3196/1-374 VSLEIRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPVTPF Shigella_3464/1-894 MNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVREKELGSIINLYVTPTTRS Salmonella_3197/1-913 LNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVREKELGSMINLYVTPTTRS Escherichia_3284/1-911 MNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVREKELGSIINLYVTPTTRS Salmonella_1825/1-491 ------------------------------------------------------------ Shigella_660/1-490 ------------------------------------------------------------ Escherichia_694/1-490 ------------------------------------------------------------ Escherichia_3283/1-374 EIMMAKIWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIFMG Salmonella_1792/1-368 QIFVGKAVPALIVATFQA-TIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLIS Yersinia_2704/1-368 QIFIGKAVPALIVATFQA-TIVLFIGIFFYQIPFAGSLALFYGTMLLYGLSLVGFGLLIS Escherichia_726/1-368 QIFIGKAVPALIVATFQA-TIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLIS Shigella_3463/1-375 EIMMAKIWSMGLVVLVVSGLSLVLMAKGVLGVPIEGSIPLFMLGVALSLFATTSIGIFMG Shigella_717/1-368 QIFIGKAVPALIVATFQA-TIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLIS Salmonella_3196/1-374 EIMMAKVWSMGLVVLVVSGLSLMLMVKGVLGVPIEGSIPLFMLGVALSLLATTSIGIFMG Shigella_3464/1-894 EFLLGKQLPYIALGMLNF-FLLCGLSVFVFGVPHKGSFLTLTLAALLYIIIATGMGLLIS Salmonella_3197/1-913 EFLLGKQLPYIALGMLNF-LLLCALSVFVFGVPLKGSFLTLTLAALLYVIIATGLGLLIS Escherichia_3284/1-911 EFLLGKQLPYIALGMLNF-FLLCGLSVFVFGVPHKGSFLTLTLAALLYIIIATGMGLLIS Salmonella_1825/1-491 ------------------------------------------------------------ Shigella_660/1-490 ------------------------------------------------------------ Escherichia_694/1-490 ------------------------------------------------------------ Escherichia_3283/1-374 TIARSMPQLGLL-VILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAILYR Salmonella_1792/1-368 SLCATQQQAFIG-VFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK Yersinia_2704/1-368 SLCSTQQQAFIG-VFVFMMPAILLSGYVSPVENMPIWLQNITWINPIRHFTDITKQIYLK Escherichia_726/1-368 SLCSTQQQAFIG-VFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK Shigella_3463/1-375 TIARSMPQLGLL-VILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAILYR Shigella_717/1-368 SLCSTQQQAFIG-VFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK Salmonella_3196/1-374 TIARSMPQLGLL-MILVLLPLQMLSGGSTPRESMPQAVQDIMLTMPTTHFVSLAQAILYR Shigella_3464/1-894 TFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGRWIGEVYPTSHFLTIARGTFSK Salmonella_3197/1-913 TFMKSQIAAIFGTSIITLIPATQFSGMIDPVASLEGPGRWIGEIYPTSHFLTIARGTFSK Escherichia_3284/1-911 TFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGRWIGEVYPTSHFLTIARGTFSK Salmonella_1825/1-491 ------------------------------------------------------------ Shigella_660/1-490 ------------------------------------------------------------ Escherichia_694/1-490 ------------------------------------------------------------ Escherichia_3283/1-374 GAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA Salmonella_1792/1-368 DASLGIVWGSLWPLLVIAATTGSAAYAMFRRKVM--- Yersinia_2704/1-368 DASFDIIWHSLWPLLVITATTGSVAYGMFRRKIA--- Escherichia_726/1-368 DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM--- Shigella_3463/1-375 GAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA Shigella_717/1-368 DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM--- Salmonella_3196/1-374 GAGLSIVWPQFLTLLAIGGVFFLIALLRFRKTIGTMA Shigella_3464/1-894 ALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG--- Salmonella_3197/1-913 ALDLSDLWPLFMPLLIAVPVVMGLSILLLKKQEG--- Escherichia_3284/1-911 ALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG--- Salmonella_1825/1-491 ------------------------------------- Shigella_660/1-490 ------------------------------------- Escherichia_694/1-490 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