F-box Protein FBXL16 Binds PP2A-B55α and Regulates Differentiation of Embryonic Stem Cells along the FLK1+ Lineage

Supplemental Data

Files in this Data Supplement:

• Supplemental Table and Figure Legends - Supplemental Table and Figure Legends
• Supplemental Figure 1 - Fbxl16 restrains differentiation of ESC into cardiomyocytes
• Supplemental Figure 2 - Confirmation of Fbxl16 knockdown
• Supplemental Figure 3 - HA-B55α and myc-FBXL16 protein analysis
• Supplemental Table 1 - Composition of murine UPS siRNA library
• Supplemental Table 2 - Complete mass spectrometry results for anti-myc immunoprecipitates recovered from transiently transfected 293 cells
• Supplemental Table 3 - Complete quantitative mass spectrometry results for phosphopeptides recovered from mouse embryonic stem cells transfected with Fbxl16 siRNA versus control (luciferase) siRNA and control 3T3 cells versus 3T3 cells stably overexpressing myc-FBXL16
• Fbxl16 Overexpression One Peptide Protein Spectra - Fbxl16 Overexpression One Peptide Protein Spectra
• Fbxl16 Overexpression Phosphorylation Spectra 1 - Fbxl16 Overexpression Phosphorylation Spectra File 1 of 2
• Fbxl16 Overexpression Phosphorylation Spectra 2 - Fbxl16 Overexpression Phosphorylation Spectra File 2 of 2
• Fbxl16 Suppression One Peptide Protein Spectra - Fbxl16 Suppression One Peptide Protein Spectra
• Fbxl16 Suppression Phosphorylation Spectra - Fbxl16 Suppression Phosphorylation Spectra