Transcription Factor Runx3 Regulates Interleukin-15-Dependent Natural Killer Cell Activation

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Fig. S1 (Runx3 expression and function in NKCs under resting conditions), S2 and S3 (Accumulation and maturation of WT and Runx3^−/− [S2] and peritoneal [S3] NKCs), S4 (uNKCs in deciduae of mice ablated of Runx3), S5 (Runx3-regulated genes that harbor Runx3 peaks overlapping T-bet peaks in Th1 cells), and S6 (Runx3 and T-bet cobinding to the Cxcr3 promoter and enhancer), Tables S1 (SqPCR primers), S2 (Presence of uNKCs at implantation sites), and S3 and S5 (Enriched ontology terms identified by GREAT [S3] and Ingenuity [S5]), and legends for Tables S4 and S6

  PDF, 5.6M

• Supplemental file 2 -

  Table S4 (Differentially expressed genes in CD11b, DP, and CD27 subpopulations)

  XLSX, 51K

• Supplemental file 3 -

  Table S6 (Runx3 candidate target genes in IL-15-cultured NK cells)

  XLSX, 56K