Fig. 6. Close ups showing the electron density for the chlorophenyl group of AR-R17477 (N-(4-(2-((3-chlorophenylmethyl) amino) ethyl) phenyl)-2-thiophecarboxamidine dihydrochloride) in complex with neuronal nitric oxide synthase (nNOS) and inducible NOS (iNOS). The pictures in upper row represent the same electron density as shown in Fig. 1. The higher s Fobs - Fcalc electron density omit maps are shown in red (3.5 s for nNOS and 4.5 s for iNOS, middle row). The lower row represent an example of low s Fobs - Fcalc omit map for two conformations of the chlorophenyl group of AR-R17477 in complex with iNOS.