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Fig. S1. Representative 3D renderings of early stages of cospecies biofilm development. Fig. S2. Exopolysaccharide synthesis in situ by GtfB adsorbed to C. albicans SC5314. Fig. S3. Amount of enzymatic activity of GtfB bound to mannan and β-glucan. Protocol S1. Assessment of GtfB binding/activity to mannan and β-glucan. Fig. S4. Supplementation with the GtfB enzyme helps to restore the phenotype/architecture of cospecies biofilms formed with the ΔgtfB::kan mutant. Fig. S5. Cospecies biofilms formed with bcr1Δ/Δ and efg1Δ/Δ mutant strains of C. albicans SN152 (reference strain). Fig. S6. Cross-sections of tongue tissues from rodent infected with S. mutans and C. albicans or C. albicans alone.
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