rank gene gband SNV.Indel HLAMP AMP HOMD HETD covered_events node_degree p.value CGC.status percentage.event as.character(p.way) 1 MAPK8 10q11.22 0 0 0 0 78 4247 2330 0 0 0.65 Adipocytokine signaling pathway(K)(0.9978436)-Alzheimer disease-amyloid secretase pathway(P)(0.9971354)-Angiogenesis(P)(0.9822336)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9685416)-Apoptosis signaling pathway(P)(0.966669)-Apoptosis(R)(0.9968012)-B cell activation(P)(0.823863)-BMP receptor signaling(N)(0.9874314)-Chagas disease(K)(0.9754598)-EGF receptor signaling pathway(P)(0.874886)-EGFR1(C)(0.9950012)-Endothelins(N)(0.9545774)-EphrinB-EPHB pathway(N)(0.9486778)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9757622)-ErbB signaling pathway(K)(0.8381482)-FAS signaling pathway (CD95)(N)(0.9268142)-FAS signaling pathway(P)(0.9799004)-Fc-epsilon receptor I signaling in mast cells(N)(0.9635456)-Focal adhesion(K)(0.9976788)-FoxO family signaling(N)(0.9901492)-Glypican pathway(N)(0.8436454)-GnRH signaling pathway(K)(0.9860102)-IFN-gamma pathway(N)(0.8901812)-IL1-mediated signaling events(N)(0.9181066)-IL12-mediated signaling events(N)(0.9962184)-IL2-mediated signaling events(N)(0.972003)-Innate Immunity Signaling(R)(0.8461868)-Insulin signaling pathway(K)(0.9985418)-Integrin signalling pathway(P)(0.9938286)-Integrins in angiogenesis(N)(0.9886312)-MAPK signaling pathway(K)(0.9978514)-NOD-like receptor signaling pathway(K)(0.9923974)-Neurotrophin signaling pathway(K)(0.966209)-Oxidative stress response(P)(0.9122228)-Pathways in cancer(K)(0.9985632)-Plasma membrane estrogen receptor signaling(N)(0.9630604)-Progesterone-mediated oocyte maturation(K)(0.991926)-Protein processing in endoplasmic reticulum(K)(0.9986644)-Proteogylcan syndecan-mediated signaling events(N)(0.9985894)-RIG-I-like receptor signaling pathway(K)(0.9932158)-Reelin signaling pathway(N)(0.9844692)-Retinoic acid receptors-mediated signaling(N)(0.9946954)-Shigellosis(K)(0.9901794)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.988555)-Signaling events regulated by Ret tyrosine kinase(N)(0.976489)-Signalling by NGF(R)(0.9925836)-T cell activation(P)(0.9725678)-TCR signaling in naive CD4+ T cells(N)(0.9828456)-TGF-beta signaling pathway(P)(0.9917086)-TGFBR(C)(0.9982196)-TNF receptor signaling pathway(N)(0.9861664)-TRAIL signaling pathway(N)(0.9249294)-Toll-like receptor signaling pathway(K)(0.9894318)-Type II diabetes mellitus(K)(0.9657112)-Wnt signaling pathway(K)(0.998343)-Wnt(C)(0.9939554)-agrin in postsynaptic differentiation(B)(0.9876316)-how progesterone initiates the oocyte maturation(B)(0.9668116)-il-10 anti-inflammatory signaling pathway(B)(0.9529192)-p75(NTR)-mediated signaling(N)(0.9937992) 2 ATP6AP1 23q28 0 0 0 5 79 3178 1412 0 0 0.7 Epithelial cell signaling in Helicobacter pylori infection(K)(0.996916)-Lysosome(K)(0.997535)-Metabolic pathways(K)(0.9972368)-Oxidative phosphorylation(K)(0.9968164)-Phagosome(K)(0.9982318)-Vibrio cholerae infection(K)(0.998329) 3 TP53 17p13.1 38 0 0 0 8 2088 1976 0 1 0.35 Amyotrophic lateral sclerosis (ALS)(K)(0.9944606)-Apoptosis signaling pathway(P)(0.9888582)-BARD1 signaling events(N)(0.9946728)-BMP receptor signaling(N)(0.9930602)-Cell Cycle Checkpoints(R)(0.99574)-Cell cycle(K)(0.996275)-Glypican pathway(N)(0.9949288)-Huntington disease(P)(0.9979746)-Huntington's disease(K)(0.9994438)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9968224)-IFN-gamma pathway(N)(0.9972934)-MAPK signaling pathway(K)(0.9985658)-Neurotrophin signaling pathway(K)(0.9940162)-Pathways in cancer(K)(0.996592)-Plasma membrane estrogen receptor signaling(N)(0.9957958)-Prostate cancer(K)(0.989622)-Signaling by Aurora kinases(N)(0.9479014)-Signaling events mediated by HDAC Class I(N)(0.99818)-TGFBR(C)(0.9979634)-TNF receptor signaling pathway(N)(0.9926202)-Wnt signaling pathway(K)(0.9969246)-Wnt signaling pathway(P)(0.9992612)-cell cycle: g1/s check point(B)(0.8359132)-hypoxia and p53 in the cardiovascular system(B)(0.9791874)-p53 signaling pathway(K)(0.994803)-p75(NTR)-mediated signaling(N)(0.9964064)-regulation of transcriptional activity by pml(B)(0.9641638)-telomeres telomerase cellular aging and immortality(B)(0.9911392)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9865712) 4 PRKX 23p22.33 0 0 0 1 75 1476 1639 0 0 0.633333333333333 Amoebiasis(K)(0.9975042)-Apoptosis(K)(0.9964216)-Calcium signaling pathway(K)(0.9993818)-Chemokine signaling pathway(K)(0.998923)-Gap junction(K)(0.991195)-Gastric acid secretion(K)(0.9923386)-GnRH signaling pathway(K)(0.9909006)-Hedgehog signaling pathway(K)(0.9938944)-Insulin signaling pathway(K)(0.9974336)-Long-term potentiation(K)(0.9642296)-MAPK signaling pathway(K)(0.99938)-Melanogenesis(K)(0.978666)-Metabotropic glutamate receptor group I pathway(P)(0.932965)-Olfactory transduction(K)(0.9978564)-Oocyte meiosis(K)(0.9932512)-Prion diseases(K)(0.9911726)-Progesterone-mediated oocyte maturation(K)(0.990535)-Salivary secretion(K)(0.9948534)-Taste transduction(K)(0.9950988)-Vascular smooth muscle contraction(K)(0.9981332)-Vasopressin-regulated water reabsorption(K)(0.995516)-Vibrio cholerae infection(K)(0.9939244)-Wnt signaling pathway(K)(0.9992834) 5 HK1 10q21.3 0 0 0 0 80 954 1383 0 0 0.666666666666667 Amino sugar and nucleotide sugar metabolism(K)(0.9956388)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.998975)-Insulin signaling pathway(K)(0.9970076)-Metabolic pathways(K)(0.9989308)-Metabolism of carbohydrates(R)(0.9987612)-Starch and sucrose metabolism(K)(0.9959478)-Type II diabetes mellitus(K)(0.9971998) 6 SMC1A 23p11.22 0 0 0 1 76 849 532 0 0 0.641666666666667 Cell cycle(K)(0.9985808)-Formation and Maturation of mRNA Transcript(R)(0.9981874)-Influenza Life Cycle(R)(0.9978394)-M Phase(R)(0.998774)-Oocyte meiosis(K)(0.9959992) 7 PTEN 10q23.31 33 0 0 7 86 817 1456 0 1 0.808333333333333 Endothelins(N)(0.990641)-Focal adhesion(K)(0.999083)-Glypican pathway(N)(0.9011942)-Hypoxia response via HIF activation(P)(0.8306744)-IFN-gamma pathway(N)(0.9969078)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9964112)-Inositol phosphate metabolism(K)(0.9940796)-Insulin/IGF pathway-protein kinase B signaling cascade(P)(0.8063912)-Nectin adhesion pathway(N)(0.9959178)-PI3 kinase pathway(P)(0.9834736)-Pathways in cancer(K)(0.9992966)-Phosphatidylinositol signaling system(K)(0.998322)-Prostate cancer(K)(0.991829)-Proteogylcan syndecan-mediated signaling events(N)(0.9966932)-S1P2 pathway(N)(0.920616)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9929836)-Signalling by NGF(R)(0.9986866)-TCR signaling in naive CD4+ T cells(N)(0.9974402)-TCR signaling(R)(0.9962156)-TRAIL signaling pathway(N)(0.9952536)-Tight junction(K)(0.99974)-ctcf: first multivalent nuclear factor(B)(0.990974)-mtor signaling pathway(B)(0.9635432)-p53 pathway(P)(0.9922446)-p53 signaling pathway(K)(0.9967328)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9909356) 8 IKBKG 23q28 0 0 0 0 79 657 1642 0 0 0.658333333333333 Adipocytokine signaling pathway(K)(0.997439)-Apoptosis(K)(0.9940742)-B cell receptor signaling pathway(K)(0.9859478)-Chagas disease(K)(0.9929246)-Chemokine signaling pathway(K)(0.9983198)-Cytosolic DNA-sensing pathway(K)(0.9967882)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9971892)-Fc-epsilon receptor I signaling in mast cells(N)(0.9911882)-Glypican pathway(N)(0.9961664)-IL12-mediated signaling events(N)(0.9944352)-IL2-mediated signaling events(N)(0.9945368)-IL23-mediated signaling events(N)(0.983094)-MAPK signaling pathway(K)(0.9989076)-NOD-like receptor signaling pathway(K)(0.9961598)-Pathways in cancer(K)(0.9986444)-Primary immunodeficiency(K)(0.997296)-Prostate cancer(K)(0.993959)-RIG-I-like receptor signaling pathway(K)(0.9947414)-Shigellosis(K)(0.9977754)-Signaling by Aurora kinases(N)(0.9733784)-Signaling events regulated by Ret tyrosine kinase(N)(0.9818644)-T cell receptor signaling pathway(K)(0.9921218)-TCR signaling in naive CD4+ T cells(N)(0.9911854)-TCR signaling(R)(0.9905992)-TNF alpha/NF-kB(C)(0.9983182)-TNF receptor signaling pathway(N)(0.9927594)-Toll-like receptor signaling pathway(K)(0.9894628)-bone remodeling(B)(0.9786954)-double stranded rna induced gene expression(B)(0.9828558)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.961536)-lectin induced complement pathway(B)(0.9842332)-p75(NTR)-mediated signaling(N)(0.9977166)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.992609)-trefoil factors initiate mucosal healing(B)(0.9760736) 9 ADRB1 10q25.3 0 0 0 0 81 602 885 0 0 0.675 Calcium signaling pathway(K)(0.9983722)-Class A/1 (Rhodopsin-like receptors)(R)(0.9970258)-Dilated cardiomyopathy(K)(0.9944398)-Endocytosis(K)(0.9981552)-Gap junction(K)(0.9960924)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9943562)-Neuroactive ligand-receptor interaction(K)(0.9986988)-Receptor-ligand complexes bind G proteins(R)(0.9933392)-Salivary secretion(K)(0.9952668) 10 ITGB1 10p11.22 0 0 2 0 71 498 1516 0 0 0.608333333333333 Angiopoietin receptor Tie2-mediated signaling(N)(0.9918892)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9897254)-Axon guidance(K)(0.9969682)-Bacterial invasion of epithelial cells(K)(0.9948854)-Cell adhesion molecules (CAMs)(K)(0.9990834)-Cell surface interactions at the vascular wall(R)(0.9991412)-Dilated cardiomyopathy(K)(0.98866)-ECM-receptor interaction(K)(0.9934064)-Focal adhesion(K)(0.995444)-Formation of Platelet plug(R)(0.9978752)-Hypertrophic cardiomyopathy (HCM)(K)(0.9895106)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9961028)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9984334)-Integrin signalling pathway(P)(0.9988392)-Leishmaniasis(K)(0.994289)-Leukocyte transendothelial migration(K)(0.984436)-Pathogenic Escherichia coli infection(K)(0.9838026)-Pathways in cancer(K)(0.997515)-Phagosome(K)(0.998959)-Proteogylcan syndecan-mediated signaling events(N)(0.9979934)-Reelin signaling pathway(N)(0.993106)-Regulation of actin cytoskeleton(K)(0.997595)-Shigellosis(K)(0.9927842)-Signaling events mediated by PRL(N)(0.9933296)-Small cell lung cancer(K)(0.9257472)-a6b1 and a6b4 Integrin signaling(N)(0.9800086)-agrin in postsynaptic differentiation(B)(0.9823854)-b cell survival pathway(B)(0.984806)-integrin signaling pathway(B)(0.9477762)-mcalpain and friends in cell motility(B)(0.9514222) 11 BTRC 10q24.32 0 0 0 0 84 447 975 0 0 0.7 APC/C-mediated degradation of cell cycle proteins(R)(0.9917424)-Circadian rhythm - mammal(K)(0.9943008)-Hedgehog signaling pathway(K)(0.9929414)-Host Interactions of HIV factors(R)(0.9986858)-Oocyte meiosis(K)(0.9982646)-Shigellosis(K)(0.99609)-TGFBR(C)(0.9986634)-TNF alpha/NF-kB(C)(0.999233)-Ubiquitin mediated proteolysis(K)(0.9983168)-Wnt signaling pathway(K)(0.9974356)-Wnt signaling pathway(P)(0.9983554)-Wnt(C)(0.9948298)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9941294)-wnt signaling pathway(B)(0.9739784) 12 TH 11p15.5 0 0 0 0 23 395 1946 0 0 0.191666666666667 BMP receptor signaling(N)(0.9892438)-Glypican pathway(N)(0.9955492)-IFN-gamma pathway(N)(0.9984242)-IL1-mediated signaling events(N)(0.9979398)-Metabolic pathways(K)(0.9981286)-Parkinson disease(P)(0.9974306)-Parkinson's disease(K)(0.9973482)-Plasma membrane estrogen receptor signaling(N)(0.997799)-Synaptic Transmission(R)(0.9918716)-TNF receptor signaling pathway(N)(0.9977388)-Tyrosine metabolism(K)(0.9852138) 13 CD40LG 23q26.3 0 0 0 0 63 378 1409 0 0 0.525 Asthma(K)(0.9599294)-BMP receptor signaling(N)(0.9949188)-Cell adhesion molecules (CAMs)(K)(0.9985458)-Cytokine-cytokine receptor interaction(K)(0.9983868)-Endothelins(N)(0.9927966)-Glypican pathway(N)(0.9961858)-IFN-gamma pathway(N)(0.9989084)-IL1-mediated signaling events(N)(0.9861942)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9958428)-Malaria(K)(0.997331)-Plasma membrane estrogen receptor signaling(N)(0.9974374)-Primary immunodeficiency(K)(0.9929712)-Systemic lupus erythematosus(K)(0.9984816)-T cell receptor signaling pathway(K)(0.9956496)-TCR signaling in naive CD4+ T cells(N)(0.9919936)-TNF receptor signaling pathway(N)(0.991139)-TRAIL signaling pathway(N)(0.9819286)-Viral myocarditis(K)(0.9975984) 14 MAPK3 16p11.2 0 0 0 0 18 344 2795 0 0 0.15 Adherens junction(K)(0.9928178)-Alzheimer disease-amyloid secretase pathway(P)(0.9496436)-Alzheimer's disease(K)(0.9948864)-Androgen-mediated signaling(N)(0.9452624)-Axon guidance(K)(0.9953778)-B cell receptor signaling pathway(K)(0.8717424)-BMP receptor signaling(N)(0.987813)-Chagas disease(K)(0.9963144)-Dorso-ventral axis formation(K)(0.9633436)-EGFR1(C)(0.9954302)-Endothelin signaling pathway(P)(0.8287298)-Endothelins(N)(0.9151784)-Fc gamma R-mediated phagocytosis(K)(0.9947946)-Fc-epsilon receptor I signaling in mast cells(N)(0.9734382)-Focal adhesion(K)(0.9694468)-IL1-mediated signaling events(N)(0.8503894)-IL4-mediated signaling events(N)(0.809351)-Insulin signaling pathway(K)(0.9917974)-Integrin signalling pathway(P)(0.9978032)-Long-term depression(K)(0.929203)-MAPK signaling pathway(K)(0.984433)-NOD-like receptor signaling pathway(K)(0.9957314)-NOTCH(C)(0.998572)-Natural killer cell mediated cytotoxicity(K)(0.9932764)-Oocyte meiosis(K)(0.9959622)-Parkinson disease(P)(0.9927482)-Pathogenic Escherichia coli infection(K)(0.8392488)-Pathways in cancer(K)(0.9984708)-Prion diseases(K)(0.9787052)-Progesterone-mediated oocyte maturation(K)(0.9732622)-Prostate cancer(K)(0.9778068)-Proteogylcan syndecan-mediated signaling events(N)(0.9993102)-Regulation of Telomerase(N)(0.996463)-Regulation of actin cytoskeleton(K)(0.9973152)-Retinoic acid receptors-mediated signaling(N)(0.9784442)-Shigellosis(K)(0.8931368)-Signaling by EGFR(R)(0.9862724)-Signaling events mediated by PRL(N)(0.9881294)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9762124)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9587372)-Signaling events regulated by Ret tyrosine kinase(N)(0.9685548)-Signalling by NGF(R)(0.986551)-T cell activation(P)(0.9824522)-T cell receptor signaling pathway(K)(0.9912194)-TGF-beta signaling pathway(K)(0.9961038)-TRAIL signaling pathway(N)(0.9115452)-Toll-like receptor signaling pathway(K)(0.989048)-Transcription(R)(0.998187)-Vascular smooth muscle contraction(K)(0.981559)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9049422)-b cell survival pathway(B)(0.9290996)-corticosteroids and cardioprotection(B)(0.9415116)-g-secretase mediated erbb4 signaling pathway(B)(0.867187)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9500782)-integrin signaling pathway(B)(0.9880218)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.8426358)-mTOR signaling pathway(K)(0.9870376)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9670628)-p75(NTR)-mediated signaling(N)(0.9874818)-phosphoinositides and their downstream targets(B)(0.9759426)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.8026076)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9309784) 15 AKT1 14q32.33 0 1 0 0 19 275 2455 3e-04 1 0.166666666666667 Adipocytokine signaling pathway(K)(0.9893022)-Androgen-mediated signaling(N)(0.9649652)-AndrogenReceptor(C)(0.9942152)-Angiogenesis(P)(0.9935458)-Angiopoietin receptor Tie2-mediated signaling(N)(0.959161)-Apoptosis signaling pathway(P)(0.9739716)-Apoptosis(K)(0.9286404)-Apoptosis(R)(0.9958656)-B cell receptor signaling pathway(K)(0.8772744)-Chemokine signaling pathway(K)(0.996344)-EGFR1(C)(0.997533)-Endothelins(N)(0.9181994)-ErbB signaling pathway(K)(0.9215876)-FAS signaling pathway(P)(0.917164)-FOXA transcription factor networks(N)(0.9783566)-Fc gamma R-mediated phagocytosis(K)(0.9975958)-Focal adhesion(K)(0.9960252)-FoxO family signaling(N)(0.9814532)-Glypican pathway(N)(0.9642102)-Huntington disease(P)(0.998179)-Hypoxia response via HIF activation(P)(0.9580942)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9960166)-IL6-mediated signaling events(N)(0.9786076)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9877844)-Insulin signaling pathway(K)(0.9918008)-Integrins in angiogenesis(N)(0.9777702)-Jak-STAT signaling pathway(K)(0.99524)-MAPK signaling pathway(K)(0.9962158)-Metabolism of nitric oxide(R)(0.9679324)-Pathways in cancer(K)(0.9967564)-Progesterone-mediated oocyte maturation(K)(0.9948236)-Prostate cancer(K)(0.9869762)-Proteogylcan syndecan-mediated signaling events(N)(0.9991984)-Reelin signaling pathway(N)(0.9686392)-Regulation of Telomerase(N)(0.9948346)-Regulation of beta-cell development(R)(0.9761032)-Retinoic acid receptors-mediated signaling(N)(0.9857528)-Signaling events mediated by PTP1B(N)(0.9587646)-Signaling events mediated by the Hedgehog family(N)(0.9850096)-Signalling by NGF(R)(0.9967906)-T cell receptor signaling pathway(K)(0.967497)-TCR signaling in naive CD4+ T cells(N)(0.9808078)-TNF alpha/NF-kB(C)(0.997633)-TRAIL signaling pathway(N)(0.823888)-Thromboxane A2 receptor signaling(N)(0.984751)-Tight junction(K)(0.9988876)-Toll-like receptor signaling pathway(K)(0.9903036)-Wnt(C)(0.9962444)-a6b1 and a6b4 Integrin signaling(N)(0.9818696)-hypoxia and p53 in the cardiovascular system(B)(0.8577752)-mTOR signaling pathway(K)(0.9876134)-p53 pathway(P)(0.9313212)-p75(NTR)-mediated signaling(N)(0.9923026)-regulation of eif2(B)(0.9440686) 16 ABCD1 23q28 0 0 0 5 78 260 216 9e-04 0 0.691666666666667 ABC transporters(K)(0.9979382)-Metabolism of lipids and lipoproteins(R)(0.9985812)-Peroxisome(K)(0.9978484)-Transmembrane transport of small molecules(R)(0.9968794) 17 AP3M1 10q22.2 0 0 0 0 82 255 321 0.0012 0 0.683333333333333 Lysosome(K)(0.9969964)-Metabolism of proteins(R)(0.9991398) 18 PIK3R1 5q13.1 11 0 0 0 6 236 2377 0.003 1 0.141666666666667 Aldosterone-regulated sodium reabsorption(K)(0.9867404)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9726936)-Apoptosis(K)(0.9109908)-B cell receptor signaling pathway(K)(0.943604)-Bacterial invasion of epithelial cells(K)(0.9908366)-Cell surface interactions at the vascular wall(R)(0.9944346)-Chagas disease(K)(0.9557542)-Chemokine signaling pathway(K)(0.9933306)-EGFR1(C)(0.9969286)-EphrinB-EPHB pathway(N)(0.8757622)-Fc gamma R-mediated phagocytosis(K)(0.9968788)-Focal adhesion(K)(0.8108752)-Hypoxia response via HIF activation(P)(0.8882882)-IFN-gamma pathway(N)(0.985989)-IL6-mediated signaling events(N)(0.9914662)-Insulin signaling pathway(K)(0.9936862)-Integrin signalling pathway(P)(0.998315)-Integrins in angiogenesis(N)(0.8674938)-Jak-STAT signaling pathway(K)(0.9959416)-Leukocyte transendothelial migration(K)(0.9923328)-NOTCH(C)(0.9937114)-Natural killer cell mediated cytotoxicity(K)(0.9857656)-Nectin adhesion pathway(N)(0.9867678)-Pathways in cancer(K)(0.999276)-Phosphatidylinositol signaling system(K)(0.9957232)-Progesterone-mediated oocyte maturation(K)(0.9961388)-Prostate cancer(K)(0.9789752)-Proteogylcan syndecan-mediated signaling events(N)(0.9950358)-Reelin signaling pathway(N)(0.9840516)-Regulation of actin cytoskeleton(K)(0.9935758)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.8874602)-Signaling events mediated by the Hedgehog family(N)(0.995885)-Signaling events regulated by Ret tyrosine kinase(N)(0.9764548)-Signalling by NGF(R)(0.9965888)-TCR signaling in naive CD4+ T cells(N)(0.982757)-TGFBR(C)(0.9988428)-TNF receptor signaling pathway(N)(0.981035)-Toll-like receptor signaling pathway(K)(0.9978556)-actions of nitric oxide in the heart(B)(0.9850642)-b cell survival pathway(B)(0.9358046)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.8075436)-il-2 receptor beta chain in t cell activation(B)(0.8417592)-mTOR signaling pathway(K)(0.9537112)-role of erbb2 in signal transduction and oncology(B)(0.9186808)-the igf-1 receptor and longevity(B)(0.9854278)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.8882402) 19 TAF5 10q24.33 0 0 0 0 84 228 254 0.0042 0 0.7 Basal transcription factors(K)(0.9960218)-Formation and Maturation of mRNA Transcript(R)(0.9992104)-HIV Life Cycle(R)(0.9977766)-Transcription(R)(0.9994712) 20 SSR4 23q28 0 0 0 5 78 213 200 0.0078 0 0.691666666666667 Insulin Synthesis and Secretion(R)(0.9983682)-Protein processing in endoplasmic reticulum(K)(0.998763) 21 UGT2B28 4q13.2 0 0 0 2 24 194 1192 0.0143 0 0.216666666666667 Metabolic pathways(K)(0.998093)-Metabolism of xenobiotics by cytochrome P450(K)(0.939322)-Porphyrin and chlorophyll metabolism(K)(0.9972864)-Retinol metabolism(K)(0.9492092)-Starch and sucrose metabolism(K)(0.99752) 22 ARHGEF6 23q26.3 0 0 0 1 75 194 859 0.0143 0 0.633333333333333 Glypican pathway(N)(0.9984024)-Pancreatic cancer(K)(0.9968902)-Regulation of actin cytoskeleton(K)(0.9984266)-Signaling by Rho GTPases(R)(0.9990892)-TRAIL signaling pathway(N)(0.9993914)-agrin in postsynaptic differentiation(B)(0.9935208) 23 POLA1 23p22.11 0 0 0 5 70 190 1321 0.0161 0 0.625 DNA replication(K)(0.9955774)-G1/S Transition(R)(0.9986778)-Metabolic pathways(K)(0.9991184)-Purine metabolism(K)(0.9976828)-Pyrimidine metabolism(K)(0.9908476)-S Phase(R)(0.9954202)-Telomere Maintenance(R)(0.9980442) 24 UGT2B17 4q13.2 0 0 1 1 40 169 1198 0.0344 0 0.35 Biological oxidations(R)(0.9917218)-Metabolic pathways(K)(0.9981808)-Metabolism of xenobiotics by cytochrome P450(K)(0.998452)-Porphyrin and chlorophyll metabolism(K)(0.9972026)-Retinol metabolism(K)(0.9973004)-Starch and sucrose metabolism(K)(0.9951294)-Steroid hormone biosynthesis(K)(0.9965924) 25 THOC2 23q25 0 0 0 4 75 167 128 0.035 0 0.658333333333333 Spliceosome(K)(0.9987362) 26 EP300 22q13.2 2 0 3 1 25 165 2220 0.0364 1 0.258333333333333 Adherens junction(K)(0.994055)-Androgen-mediated signaling(N)(0.972551)-AndrogenReceptor(C)(0.9942002)-BMP receptor signaling(N)(0.9872522)-Cell cycle(K)(0.998691)-Endothelins(N)(0.9920162)-FOXA transcription factor networks(N)(0.9491372)-FOXM1 transcription factor network(N)(0.9947858)-FoxO family signaling(N)(0.9920968)-Glypican pathway(N)(0.9943714)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.995325)-Huntington disease(P)(0.9982382)-Huntington's disease(K)(0.996111)-Hypoxia response via HIF activation(P)(0.9693938)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9975528)-IFN-gamma pathway(N)(0.996292)-IL1-mediated signaling events(N)(0.98401)-Jak-STAT signaling pathway(K)(0.9963974)-KitReceptor(C)(0.988674)-Long-term potentiation(K)(0.9890404)-Melanogenesis(K)(0.856388)-NOTCH(C)(0.9949918)-Notch signaling pathway(K)(0.9929346)-Pathways in cancer(K)(0.9989384)-Plasma membrane estrogen receptor signaling(N)(0.9876346)-Prostate cancer(K)(0.9752746)-Regulation of retinoblastoma protein(N)(0.9939236)-Renal cell carcinoma(K)(0.9814384)-Retinoic acid receptors-mediated signaling(N)(0.9777044)-Signaling events mediated by HDAC Class I(N)(0.9972542)-TGF-beta signaling pathway(K)(0.9927008)-TGF-beta signaling pathway(P)(0.9775536)-TGFBR(C)(0.9959022)-TNF receptor signaling pathway(N)(0.9925506)-TRAIL signaling pathway(N)(0.9383186)-Wnt signaling pathway(K)(0.9929846)-Wnt signaling pathway(P)(0.9986676)-Wnt(C)(0.994276)-cell cycle: g2/m checkpoint(B)(0.919912)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9663072)-nfat and hypertrophy of the heart (B)(0.977499)-regulation of transcriptional activity by pml(B)(0.963313)-role of erbb2 in signal transduction and oncology(B)(0.9028098)-the information processing pathway at the ifn beta enhancer(B)(0.9849714) 27 ACTA2 10q23.31 0 0 0 4 83 152 620 0.053 0 0.725 Alzheimer disease-presenilin pathway(P)(0.9978886)-Huntington disease(P)(0.9966346)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9969434)-Vascular smooth muscle contraction(K)(0.9989824)-Wnt signaling pathway(P)(0.9985502) 28 CDC2 10q21.2 0 0 0 0 75 141 489 0.0676 0 0.625 APC/C-mediated degradation of cell cycle proteins(R)(0.9852974)-AndrogenReceptor(C)(0.9973234)-Cell Cycle Checkpoints(R)(0.995143)-FOXM1 transcription factor network(N)(0.996318)-G1/S Transition(R)(0.9951532)-G2/M Transition(R)(0.9992638)-Hedgehog(C)(0.9954612)-Retinoic acid receptors-mediated signaling(N)(0.993225)-TGFBR(C)(0.9984156)-Wnt(C)(0.9981614)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.995229) 29 HTR2C 23q23 0 0 0 6 68 141 650 0.0676 0 0.616666666666667 Calcium signaling pathway(K)(0.9975406)-Class A/1 (Rhodopsin-like receptors)(R)(0.9989686)-Gap junction(K)(0.9979192)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9982264)-Neuroactive ligand-receptor interaction(K)(0.9987826)-Receptor-ligand complexes bind G proteins(R)(0.989989)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9983218)-chrebp regulation by carbohydrates and camp(B)(0.998181)-ion channels and their functional role in vascular endothelium(B)(0.9976438)-roles of ß arrestin dependent recruitment of src kinases in gpcr signaling(B)(0.9723974)-ß-arrestins in gpcr desensitization(B)(0.9358726) 30 EXOSC1 10q24.1 0 0 0 0 79 135 59 0.0782 0 0.658333333333333 RNA degradation(K)(0.9986888) 31 DGKH 13q14.11 0 0 0 0 37 133 1164 0.0799 0 0.308333333333333 Glycerolipid metabolism(K)(0.9290092)-Glycerophospholipid metabolism(K)(0.9973826)-Metabolic pathways(K)(0.9981626)-Phosphatidylinositol signaling system(K)(0.9976188) 32 HSPA2 14q23.3 0 0 0 0 21 128 827 0.0884 0 0.175 Antigen processing and presentation(K)(0.9965124)-Endocytosis(K)(0.9990416)-MAPK signaling pathway(K)(0.996299)-Parkinson disease(P)(0.9985422)-Protein processing in endoplasmic reticulum(K)(0.9994504)-Spliceosome(K)(0.998636) 33 RPL10 23q28 0 0 0 5 79 125 313 0.0923 0 0.7 Influenza Life Cycle(R)(0.9987062)-Metabolism of proteins(R)(0.9992116)-Ribosome(K)(0.9943142) 34 ECHS1 10q26.3 0 0 0 1 79 121 1281 0.0994 0 0.666666666666667 Butanoate metabolism(K)(0.993961)-Fatty acid metabolism(K)(0.9976648)-Lysine degradation(K)(0.9970532)-Metabolic pathways(K)(0.998391)-Metabolism of amino acids(R)(0.9977722)-Metabolism of lipids and lipoproteins(R)(0.9979416)-Tryptophan metabolism(K)(0.9974314) 35 POLE2 14q22.1 0 0 0 0 21 118 1391 0.1045 0 0.175 Base excision repair(K)(0.9957996)-DNA Repair(R)(0.9991482)-DNA replication(K)(0.9974572)-G1/S Transition(R)(0.997002)-Metabolic pathways(K)(0.9979082)-Nucleotide excision repair(K)(0.997978)-Purine metabolism(K)(0.9975498)-Pyrimidine metabolism(K)(0.9050556)-S Phase(R)(0.9977338)-Telomere Maintenance(R)(0.9969576) 36 CAMK2G 10q22.2 0 0 0 0 79 115 1485 0.1098 0 0.658333333333333 Calcium signaling pathway(K)(0.9996008)-ErbB signaling pathway(K)(0.9947316)-Gastric acid secretion(K)(0.9977414)-Glioma(K)(0.986297)-Glypican pathway(N)(0.9918622)-GnRH signaling pathway(K)(0.9987326)-IFN-gamma pathway(N)(0.9964496)-Long-term potentiation(K)(0.9867666)-Melanogenesis(K)(0.99251)-Neurotrophin signaling pathway(K)(0.998611)-Olfactory transduction(K)(0.9985088)-Oocyte meiosis(K)(0.9984392)-TGFBR(C)(0.9986158)-TRAIL signaling pathway(N)(0.9969506)-Wnt signaling pathway(K)(0.9984354)-Wnt(C)(0.9972822)-bioactive peptide induced signaling pathway(B)(0.9858922)-regulation of pgc-1a(B)(0.9918608)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9961778) 37 L1CAM 23q28 0 0 0 5 78 114 333 0.1098 0 0.691666666666667 Axon guidance(K)(0.9983138)-Cell adhesion molecules (CAMs)(K)(0.997966)-Cell surface interactions at the vascular wall(R)(0.99666) 38 PSTK 10q26.13 0 0 0 0 80 111 41 0.1152 0 0.666666666666667 Aminoacyl-tRNA biosynthesis(K)(0.9985032) 39 IFNA5 9p21.3 0 0 1 24 38 109 615 0.1184 0 0.525 Autoimmune thyroid disease(K)(0.9927252)-Cytokine-cytokine receptor interaction(K)(0.9989464)-Cytosolic DNA-sensing pathway(K)(0.997308)-Jak-STAT signaling pathway(K)(0.9989098)-Natural killer cell mediated cytotoxicity(K)(0.9994022)-RIG-I-like receptor signaling pathway(K)(0.9957002)-Regulation of autophagy(K)(0.9960588)-TCR signaling in naive CD8+ T cells(N)(0.9961394)-Toll-like receptor signaling pathway(K)(0.9981374) 40 NUP98 11p15.4 0 0 0 0 12 106 512 0.1239 1 0.1 HIV Life Cycle(R)(0.998391)-Host Interactions of HIV factors(R)(0.9950048)-Influenza Life Cycle(R)(0.9982732)-M Phase(R)(0.9987208)-Metabolism of carbohydrates(R)(0.9985608)-Metabolism of non-coding RNA(R)(0.9925998)-Transport of Mature Transcript to Cytoplasm(R)(0.9809204) 41 RBBP7 23p22.2 0 0 0 4 75 103 726 0.1293 0 0.658333333333333 EGFR1(C)(0.99728)-Glypican pathway(N)(0.998564)-IFN-gamma pathway(N)(0.997714)-Regulation of Telomerase(N)(0.9973802)-Signaling events mediated by HDAC Class I(N)(0.9987096)-Signaling events mediated by the Hedgehog family(N)(0.9969752) 42 MAOA 23p11.3 0 0 0 4 75 95 1213 0.1516 0 0.658333333333333 Biological oxidations(R)(0.9977704)-Drug metabolism - cytochrome P450(K)(0.9981218)-Glycine, serine and threonine metabolism(K)(0.9935714)-Histidine metabolism(K)(0.9263542)-Metabolic pathways(K)(0.9978044)-Synaptic Transmission(R)(0.9974438)-Tryptophan metabolism(K)(0.9966368) 43 F2 11p11.2 0 0 0 0 10 85 1288 0.185 0 0.0833333333333333 Angiopoietin receptor Tie2-mediated signaling(N)(0.9955684)-Cell surface interactions at the vascular wall(R)(0.997927)-Class A/1 (Rhodopsin-like receptors)(R)(0.8949222)-FOXA transcription factor networks(N)(0.9842478)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.8687918)-Formation of Platelet plug(R)(0.997119)-Metabolism of proteins(R)(0.9971302)-Neuroactive ligand-receptor interaction(K)(0.9986882)-Proteogylcan syndecan-mediated signaling events(N)(0.9986746)-Regulation of actin cytoskeleton(K)(0.9979672)-chrebp regulation by carbohydrates and camp(B)(0.9752148)-cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway(B)(0.9126764)-ion channels and their functional role in vascular endothelium(B)(0.8928662) 44 IL2RG 23q13.1 0 0 0 0 78 80 914 0.1966 0 0.65 Cytokine-cytokine receptor interaction(K)(0.9986498)-Endocytosis(K)(0.9984812)-IFN-gamma pathway(N)(0.9974244)-IL12-mediated signaling events(N)(0.9974754)-IL2-mediated signaling events(N)(0.9959318)-Jak-STAT signaling pathway(K)(0.9979064)-Primary immunodeficiency(K)(0.998136)-TCR signaling in naive CD8+ T cells(N)(0.993826)-il-2 receptor beta chain in t cell activation(B)(0.995091) 45 ACTN1 14q24.1 0 0 0 0 23 80 1034 0.1966 0 0.191666666666667 Adherens junction(K)(0.9988608)-Amoebiasis(K)(0.9954566)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9934878)-Focal adhesion(K)(0.9955704)-Formation of Platelet plug(R)(0.9983924)-Integrin signalling pathway(P)(0.9976542)-Leukocyte transendothelial migration(K)(0.9978536)-Nectin adhesion pathway(N)(0.9567304)-Proteogylcan syndecan-mediated signaling events(N)(0.99478)-Regulation of actin cytoskeleton(K)(0.9983534)-Systemic lupus erythematosus(K)(0.9983236)-Tight junction(K)(0.9979836)-integrin signaling pathway(B)(0.9960902) 46 PDHA1 23p22.12 0 0 0 1 78 75 1243 0.2129 0 0.658333333333333 Butanoate metabolism(K)(0.9944332)-Glucose Regulation of Insulin Secretion(R)(0.998244)-Metabolic pathways(K)(0.9982198)-Metabolism of carbohydrates(R)(0.9985954)-Pyruvate metabolism(K)(0.9958454)-Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9960884)-Valine, leucine and isoleucine biosynthesis(K)(0.9968592) 47 ACSL5 10q25.2 0 0 0 0 81 74 1259 0.2129 0 0.675 Adipocytokine signaling pathway(K)(0.9978218)-Metabolic pathways(K)(0.998654)-PPAR signaling pathway(K)(0.997832)-Peroxisome(K)(0.9986648) 48 FLNA 23q28 0 0 0 5 76 70 771 0.2264 0 0.675 AndrogenReceptor(C)(0.9965148)-Focal adhesion(K)(0.9988758)-Further platelet releasate(R)(0.9983566)-Integrin signalling pathway(P)(0.9982986)-MAPK signaling pathway(K)(0.9995156)-PNAT(P)(0.995152)-TCR signaling in naive CD4+ T cells(N)(0.9973472)-TNF alpha/NF-kB(C)(0.9972518) 49 UBA1 23p11.3 0 0 0 1 76 65 261 0.2455 0 0.641666666666667 Parkinson's disease(K)(0.998292)-Ubiquitin mediated proteolysis(K)(0.999217) 50 TRAF6 11p12 0 1 0 0 6 64 1741 0.2455 0 0.0583333333333333 Chagas disease(K)(0.9706626)-Endocytosis(K)(0.9982832)-Glypican pathway(N)(0.9514168)-IFN-gamma pathway(N)(0.911809)-IL27-mediated signaling events(N)(0.9771838)-MAPK signaling pathway(K)(0.9969492)-NOD-like receptor signaling pathway(K)(0.9977848)-Pathways in cancer(K)(0.998104)-Plasma membrane estrogen receptor signaling(N)(0.82786)-RIG-I-like receptor signaling pathway(K)(0.996547)-Signaling by Aurora kinases(N)(0.953064)-Signaling events regulated by Ret tyrosine kinase(N)(0.9929682)-TNF alpha/NF-kB(C)(0.9980746)-TNF receptor signaling pathway(N)(0.9892244)-Toll-like receptor signaling pathway(K)(0.9908174)-Ubiquitin mediated proteolysis(K)(0.9988246)-p75(NTR)-mediated signaling(N)(0.989917) 51 CETN2 23q28 0 0 0 1 76 61 123 0.247 0 0.641666666666667 G2/M Transition(R)(0.9977422)-Nucleotide excision repair(K)(0.9984072) 52 BUB3 10q26.13 0 0 0 0 82 61 277 0.247 0 0.683333333333333 APC/C-mediated degradation of cell cycle proteins(R)(0.9805646)-Cell Cycle Checkpoints(R)(0.9971168)-Cell cycle(K)(0.997035)-M Phase(R)(0.9987626) 53 MED12 23q13.1 0 0 0 0 78 60 33 0.247 1 0.65 Generic Transcription Pathway(R)(0.9993478) 54 ARHGAP19 10q24.1 0 0 0 0 79 60 125 0.247 0 0.658333333333333 Signaling by Rho GTPases(R)(0.998304) 55 H2AFY2 10q22.1 0 0 0 0 81 59 139 0.2479 0 0.675 Systemic lupus erythematosus(K)(0.9975428) 56 F8 23q28 0 0 0 4 75 58 179 0.2488 0 0.658333333333333 Complement and coagulation cascades(K)(0.9990718)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9971198)-Formation of Platelet plug(R)(0.9987906)-intrinsic prothrombin activation pathway(B)(0.9983756) 57 PLA2G12B 10q22.1 0 0 0 0 84 54 1602 0.2652 0 0.7 Arachidonic acid metabolism(K)(0.9952204)-Fc epsilon RI signaling pathway(K)(0.9964284)-Glycerophospholipid metabolism(K)(0.9976044)-GnRH signaling pathway(K)(0.9973034)-Long-term depression(K)(0.9975634)-MAPK signaling pathway(K)(0.9981924)-Metabolic pathways(K)(0.9984694)-Pancreatic secretion(K)(0.9984718)-VEGF signaling pathway(K)(0.9963684)-Vascular smooth muscle contraction(K)(0.9981732) 58 VTI1A 10q25.2 0 0 0 0 81 52 36 0.269 1 0.675 SNARE interactions in vesicular transport(K)(0.9983682) 59 RB1 13q14.2 9 0 0 3 38 51 1060 0.269 1 0.35 AndrogenReceptor(C)(0.9985976)-Cell cycle(K)(0.998168)-DNA Replication(R)(0.9410492)-FAS signaling pathway (CD95)(N)(0.9245194)-FOXM1 transcription factor network(N)(0.995026)-G1/S Transition(R)(0.9917936)-Glioma(K)(0.9889664)-ID(C)(0.9952868)-Pathways in cancer(K)(0.997539)-Prostate cancer(K)(0.995902)-Regulation of retinoblastoma protein(N)(0.997115)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9853756)-TGFBR(C)(0.9984616)-TNF receptor signaling pathway(N)(0.9979126)-TRAIL signaling pathway(N)(0.997812)-il-2 receptor beta chain in t cell activation(B)(0.9888856)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.996211)-rb tumor suppressor/checkpoint signaling in response to dna damage(B)(0.8052776)-regulation of transcriptional activity by pml(B)(0.9588948)-telomeres telomerase cellular aging and immortality(B)(0.9922108)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9898682) 60 CLTA 9p13.3 0 0 1 0 20 51 1641 0.269 0 0.175 Bacterial invasion of epithelial cells(K)(0.9936654)-Endocytosis(K)(0.9990768)-Gap junction trafficking and regulation(R)(0.9947988)-Glypican pathway(N)(0.9628518)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9965472)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.996934)-Huntington disease(P)(0.9963828)-Huntington's disease(K)(0.9963164)-Influenza Life Cycle(R)(0.9968304)-Lysosome(K)(0.997722)-Membrane Trafficking(R)(0.9927362)-Plasma membrane estrogen receptor signaling(N)(0.9924974)-Proteogylcan syndecan-mediated signaling events(N)(0.9986782)-Signaling by EGFR(R)(0.8375016)-Signalling by NGF(R)(0.9975506)-TRAIL signaling pathway(N)(0.9972396)-adp-ribosylation factor(B)(0.9941604) 61 EGFR 7p11.2 20 43 11 3 1 48 1700 0.2777 1 0.491666666666667 Adherens junction(K)(0.9930396)-Alpha6Beta4Integrin(C)(0.9925266)-Calcium signaling pathway(K)(0.9973968)-Canonical NF-kappaB pathway(N)(0.9074536)-Cytokine-cytokine receptor interaction(K)(0.9996096)-Dorso-ventral axis formation(K)(0.9910046)-EGF receptor signaling pathway(P)(0.9876906)-EGFR1(C)(0.9991352)-Endocytosis(K)(0.9980034)-Endothelins(N)(0.9775446)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9952596)-ErbB signaling pathway(K)(0.986519)-Focal adhesion(K)(0.9968664)-Gap junction(K)(0.9983836)-GnRH signaling pathway(K)(0.991113)-MAPK signaling pathway(K)(0.999047)-Pathways in cancer(K)(0.9992538)-Plasma membrane estrogen receptor signaling(N)(0.983218)-Prostate cancer(K)(0.981727)-Proteogylcan syndecan-mediated signaling events(N)(0.9940206)-Regulation of Telomerase(N)(0.9977694)-Regulation of actin cytoskeleton(K)(0.9967612)-Signaling by EGFR(R)(0.8716228)-Signaling events mediated by PTP1B(N)(0.9908798)-Thromboxane A2 receptor signaling(N)(0.9930924)-a6b1 and a6b4 Integrin signaling(N)(0.9883364) 62 INS 11p15.5 0 0 0 0 23 47 1454 0.2777 0 0.191666666666667 Aldosterone-regulated sodium reabsorption(K)(0.9887608)-Endothelins(N)(0.9928038)-FOXA transcription factor networks(N)(0.9669948)-Glucose Regulation of Insulin Secretion(R)(0.9991486)-Glypican pathway(N)(0.9069294)-IFN-gamma pathway(N)(0.9989178)-Insulin Synthesis and Secretion(R)(0.9982352)-Insulin signaling pathway(K)(0.998045)-Maturity onset diabetes of the young(K)(0.9782156)-Oocyte meiosis(K)(0.9969248)-Progesterone-mediated oocyte maturation(K)(0.9932012)-Prostate cancer(K)(0.9948344)-Proteogylcan syndecan-mediated signaling events(N)(0.9991142)-Regulation of actin cytoskeleton(K)(0.9983526)-Regulation of autophagy(K)(0.9946302)-Regulation of beta-cell development(R)(0.992169)-Signaling events mediated by PTP1B(N)(0.9952404)-TRAIL signaling pathway(N)(0.9985392)-Type I diabetes mellitus(K)(0.9928454)-Type II diabetes mellitus(K)(0.9642774)-growth hormone signaling pathway(B)(0.8907042)-mTOR signaling pathway(K)(0.987785) 63 PDCD1 2q37.3 0 0 0 0 12 47 234 0.2777 0 0.1 Cell adhesion molecules (CAMs)(K)(0.9992564)-T cell receptor signaling pathway(K)(0.9975892) 64 OR52N5 11p15.4 0 0 0 2 24 45 389 0.2806 0 0.216666666666667 Olfactory transduction(K)(0.998484) 65 POLR2L 11p15.5 0 0 0 0 31 44 1755 0.2806 0 0.258333333333333 DNA Repair(R)(0.9974418)-Formation and Maturation of mRNA Transcript(R)(0.9980004)-HIV Life Cycle(R)(0.9968558)-Huntington's disease(K)(0.9978128)-Influenza Life Cycle(R)(0.9966432)-Metabolic pathways(K)(0.999168)-Purine metabolism(K)(0.9944164)-Pyrimidine metabolism(K)(0.892934)-Regulatory RNA pathways(R)(0.8064294)-TNF alpha/NF-kB(C)(0.9994106)-Transcription(R)(0.9985788) 66 AP1S2 23p22.2 0 0 0 7 71 43 264 0.2806 0 0.65 Host Interactions of HIV factors(R)(0.9994344)-Lysosome(K)(0.998059)-Membrane Trafficking(R)(0.9987398) 67 PAPOLA 14q32.2 0 0 0 0 21 43 253 0.2806 0 0.175 Formation and Maturation of mRNA Transcript(R)(0.9982682)-RNA degradation(K)(0.9969486)-Transcription(R)(0.9973616) 68 SUV39H1 23p11.23 0 0 0 1 77 43 104 0.2806 0 0.65 Lysine degradation(K)(0.9986204)-Regulation of retinoblastoma protein(N)(0.997832) 69 IL2RA 10p15.1 0 0 2 0 71 41 1302 0.2893 0 0.608333333333333 BMP receptor signaling(N)(0.9967948)-Cytokine-cytokine receptor interaction(K)(0.9975208)-Endocytosis(K)(0.9993846)-Endothelins(N)(0.9931098)-Glypican pathway(N)(0.9432652)-Hematopoietic cell lineage(K)(0.9985916)-IFN-gamma pathway(N)(0.9955878)-IL1-mediated signaling events(N)(0.9692808)-IL12-mediated signaling events(N)(0.9453038)-IL2-mediated signaling events(N)(0.969741)-Interleukin signaling pathway(P)(0.9878222)-Jak-STAT signaling pathway(K)(0.9965742)-Plasma membrane estrogen receptor signaling(N)(0.9984246)-Proteogylcan syndecan-mediated signaling events(N)(0.9974704)-TCR signaling in naive CD4+ T cells(N)(0.993567)-TNF receptor signaling pathway(N)(0.9964076)-TRAIL signaling pathway(N)(0.96055)-il-2 receptor beta chain in t cell activation(B)(0.991893) 70 NR0B1 23p21.2 0 0 0 7 67 40 151 0.2913 0 0.616666666666667 Androgen-mediated signaling(N)(0.9909316)-NR transcription pathway(R)(0.998402) 71 IFNG 12q15 0 3 0 0 11 39 1546 0.2937 0 0.116666666666667 Amoebiasis(K)(0.9950976)-Antigen processing and presentation(K)(0.9963678)-BMP receptor signaling(N)(0.9750918)-Cytokine-cytokine receptor interaction(K)(0.9988072)-Endothelins(N)(0.9619494)-Glypican pathway(N)(0.9639364)-IFN-gamma pathway(N)(0.840942)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.99358)-Jak-STAT signaling pathway(K)(0.8012256)-Malaria(K)(0.9935434)-Proteasome(K)(0.990673)-Regulation of Telomerase(N)(0.9947292)-Regulation of autophagy(K)(0.9960718)-Systemic lupus erythematosus(K)(0.9986568)-T cell receptor signaling pathway(K)(0.9902206)-TGF-beta signaling pathway(K)(0.995111)-TNF receptor signaling pathway(N)(0.9983648) 72 GATA1 23p11.23 0 0 0 1 77 38 159 0.2964 1 0.65 NOTCH(C)(0.996632)-Signaling events mediated by HDAC Class I(N)(0.9971368)-hemoglobins chaperone(B)(0.9966504) 73 GLUD2 23q24 0 0 0 4 74 35 1153 0.3155 0 0.65 Metabolic pathways(K)(0.9990432)-Nitrogen metabolism(K)(0.9970278)-Proximal tubule bicarbonate reclamation(K)(0.998753) 74 ELK1 23p11.23 0 0 0 1 76 34 1404 0.3155 0 0.641666666666667 Angiopoietin receptor Tie2-mediated signaling(N)(0.9953928)-EGFR1(C)(0.9971982)-Endometrial cancer(K)(0.9948664)-ErbB signaling pathway(K)(0.9924004)-Focal adhesion(K)(0.9982134)-Glypican pathway(N)(0.833027)-GnRH signaling pathway(K)(0.9955176)-ID(C)(0.9967794)-Insulin signaling pathway(K)(0.997663)-Leishmaniasis(K)(0.9986616)-MAPK signaling pathway(K)(0.9978092)-Oxidative stress response(P)(0.9861336)-Parkinson disease(P)(0.998022)-Prion diseases(K)(0.9964062)-Proteogylcan syndecan-mediated signaling events(N)(0.9973934)-S1P2 pathway(N)(0.8143818)-Signalling by NGF(R)(0.9950912)-TCR signaling in naive CD4+ T cells(N)(0.991045)-TRAIL signaling pathway(N)(0.9974574)-fc epsilon receptor i signaling in mast cells(B)(0.9243996)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9875338)-p38 mapk signaling pathway(B)(0.987215)-p75(NTR)-mediated signaling(N)(0.9948236)-t cell receptor signaling pathway(B)(0.9881408)-toll-like receptor pathway(B)(0.994829)-tpo signaling pathway(B)(0.9683066) 75 SMNDC1 10q25.2 0 0 0 0 81 34 128 0.3155 0 0.675 Spliceosome(K)(0.9995598) 76 PLCB3 11q13.1 0 0 0 0 26 33 2296 0.3166 0 0.216666666666667 Alzheimer's disease(K)(0.9978306)-Amoebiasis(K)(0.9986776)-Calcium signaling pathway(K)(0.9981438)-Chagas disease(K)(0.9983264)-Chemokine signaling pathway(K)(0.9964826)-Endothelin signaling pathway(P)(0.9872498)-Gap junction(K)(0.9962184)-Gastric acid secretion(K)(0.9756638)-GnRH signaling pathway(K)(0.991709)-Huntington's disease(K)(0.9982674)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9941696)-LPA receptor mediated events(N)(0.9902408)-Metabolic pathways(K)(0.9994744)-Salivary secretion(K)(0.9919492)-Vascular smooth muscle contraction(K)(0.996333)-Wnt signaling pathway(K)(0.9984624)-Wnt signaling pathway(P)(0.9990292) 77 ERCC6 10q11.23 0 0 0 0 77 32 94 0.3166 0 0.641666666666667 DNA Repair(R)(0.9976178)-Nucleotide excision repair(K)(0.9981914) 78 PPP3CB 10q22.2 0 0 0 0 85 32 1540 0.3166 0 0.708333333333333 Alzheimer's disease(K)(0.9976226)-Amyotrophic lateral sclerosis (ALS)(K)(0.9952986)-Apoptosis(K)(0.995276)-Axon guidance(K)(0.9961888)-B cell activation(P)(0.8473504)-B cell receptor signaling pathway(K)(0.9931458)-Calcium signaling pathway(K)(0.998562)-Glypican pathway(N)(0.9968956)-Long-term potentiation(K)(0.9900436)-MAPK signaling pathway(K)(0.9978594)-Natural killer cell mediated cytotoxicity(K)(0.9953754)-Oocyte meiosis(K)(0.997194)-Opioid Signalling(R)(0.9957414)-T cell activation(P)(0.9667922)-T cell receptor signaling pathway(K)(0.9961132)-TRAIL signaling pathway(N)(0.9961474)-VEGF signaling pathway(K)(0.9890272)-Wnt signaling pathway(K)(0.9978888)-Wnt signaling pathway(P)(0.99626) 79 RHOG 11p15.4 0 0 0 0 12 32 343 0.3166 0 0.1 Bacterial invasion of epithelial cells(K)(0.9980764)-Huntington disease(P)(0.9968482)-Shigellosis(K)(0.9967006)-Signaling by Rho GTPases(R)(0.9992234) 80 RPA4 23q21.33 0 0 0 8 65 29 172 0.3413 0 0.608333333333333 DNA Replication(R)(0.9518194)-DNA replication(K)(0.9927694)-G1/S Transition(R)(0.9980128)-Homologous recombination(K)(0.9986252)-Mismatch repair(K)(0.9979624)-Nucleotide excision repair(K)(0.9988288) 81 ATP5C1 10p14 0 0 2 0 68 28 1338 0.3476 0 0.583333333333333 Alzheimer's disease(K)(0.9982332)-Glucose Regulation of Insulin Secretion(R)(0.9989408)-Huntington's disease(K)(0.9986764)-Metablism of nucleotides(R)(0.9981696)-Metabolic pathways(K)(0.9987826)-Oxidative phosphorylation(K)(0.9959338)-Parkinson's disease(K)(0.9979126) 82 WARS 14q32.2 0 0 0 0 19 27 82 0.3509 0 0.158333333333333 Aminoacyl-tRNA biosynthesis(K)(0.9986744)-Tryptophan metabolism(K)(0.9965562)-tRNA Aminoacylation(R)(0.832155) 83 CTBP2 10q26.13 0 0 0 0 83 27 683 0.3509 0 0.691666666666667 Chronic myeloid leukemia(K)(0.995297)-Notch signaling pathway(K)(0.9981394)-Pathways in cancer(K)(0.9992264)-Wnt signaling pathway(K)(0.9983242)-Wnt signaling pathway(P)(0.9985672)-Wnt(C)(0.997898) 84 CYP2C18 10q23.33 0 0 0 0 81 26 1243 0.3595 0 0.675 Arachidonic acid metabolism(K)(0.9944444)-Biological oxidations(R)(0.9968104)-Drug metabolism - cytochrome P450(K)(0.9952622)-FOXA transcription factor networks(N)(0.9806576)-Metabolic pathways(K)(0.9994534)-Metabolism of xenobiotics by cytochrome P450(K)(0.9826362)-Retinol metabolism(K)(0.9946012) 85 SEC61A2 10p14 0 0 2 0 72 25 377 0.3642 0 0.616666666666667 Insulin Synthesis and Secretion(R)(0.9976346)-Phagosome(K)(0.9982298)-Protein export(K)(0.99587)-Protein processing in endoplasmic reticulum(K)(0.9987218)-Vibrio cholerae infection(K)(0.9951698) 86 PIK3CA 3q26.32 6 3 0 0 0 25 2397 0.3642 1 0.075 Aldosterone-regulated sodium reabsorption(K)(0.9830844)-Alpha6Beta4Integrin(C)(0.9901862)-Amoebiasis(K)(0.9899196)-Apoptosis(K)(0.931799)-B cell receptor signaling pathway(K)(0.9743382)-Bacterial invasion of epithelial cells(K)(0.9462762)-Cell surface interactions at the vascular wall(R)(0.996241)-EGFR1(C)(0.9974346)-Endothelin signaling pathway(P)(0.8856522)-EphrinB-EPHB pathway(N)(0.8334022)-Fc gamma R-mediated phagocytosis(K)(0.9972218)-Focal adhesion(K)(0.9748502)-Glucagon signaling in metabolic regulation(R)(0.8289728)-Glypican pathway(N)(0.9445716)-IL6-mediated signaling events(N)(0.9937678)-Insulin signaling pathway(K)(0.9965664)-Leukocyte transendothelial migration(K)(0.9880466)-Pathways in cancer(K)(0.9990292)-Phosphatidylinositol signaling system(K)(0.9714788)-Progesterone-mediated oocyte maturation(K)(0.9953324)-Proteogylcan syndecan-mediated signaling events(N)(0.8105122)-Reelin signaling pathway(N)(0.9727242)-Regulation of actin cytoskeleton(K)(0.9946962)-Signaling by EGFR(R)(0.9876038)-Signaling events mediated by the Hedgehog family(N)(0.965347)-Signaling events regulated by Ret tyrosine kinase(N)(0.9887644)-Signalling by NGF(R)(0.8941484)-TNF receptor signaling pathway(N)(0.9800908)-Toll-like receptor signaling pathway(K)(0.9782414)-a6b1 and a6b4 Integrin signaling(N)(0.9115844)-b cell survival pathway(B)(0.9358506)-mTOR signaling pathway(K)(0.9887772)-nfat and hypertrophy of the heart (B)(0.9259284)-p53 pathway(P)(0.9394348)-p75(NTR)-mediated signaling(N)(0.960753)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9709756) 87 ABCD4 14q24.3 0 0 0 0 24 24 118 0.3662 0 0.2 ABC transporters(K)(0.997524)-Peroxisome(K)(0.9990988) 88 YWHAE 17p13.3 0 0 0 0 5 24 1333 0.3662 0 0.0416666666666667 BMP receptor signaling(N)(0.9941412)-Cell cycle(K)(0.9974884)-Endothelins(N)(0.977296)-G2/M Transition(R)(0.9988812)-Glypican pathway(N)(0.9740838)-IFN-gamma pathway(N)(0.8555962)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9879078)-Neurotrophin signaling pathway(K)(0.920336)-Oocyte meiosis(K)(0.9955412)-Parkinson disease(P)(0.9967512)-Proteogylcan syndecan-mediated signaling events(N)(0.9553394)-Regulation of Telomerase(N)(0.9952584)-Signaling events mediated by HDAC Class I(N)(0.9958912)-Signalling by NGF(R)(0.9946748)-TRAIL signaling pathway(N)(0.99121)-a6b1 and a6b4 Integrin signaling(N)(0.9885798)-p75(NTR)-mediated signaling(N)(0.9905522)-sprouty regulation of tyrosine kinase signals(B)(0.8453108) 89 GK 23p21.2 0 0 0 6 69 24 1219 0.3662 0 0.625 Metabolic pathways(K)(0.9975078)-Metabolism of lipids and lipoproteins(R)(0.99885)-PPAR signaling pathway(K)(0.9985656) 90 APEX2 23p11.21 0 0 0 3 72 23 34 0.3756 0 0.625 Base excision repair(K)(0.9989158) 91 MAPK14 6p21.31 0 1 0 0 4 22 2069 0.3756 0 0.0416666666666667 Alzheimer disease-amyloid secretase pathway(P)(0.996438)-Amyotrophic lateral sclerosis (ALS)(K)(0.9969576)-Angiogenesis(P)(0.9932118)-EGF receptor signaling pathway(P)(0.8559508)-EGFR1(C)(0.9985476)-Glypican pathway(N)(0.9768554)-IL6-mediated signaling events(N)(0.9420754)-Leukocyte transendothelial migration(K)(0.994623)-MAPK signaling pathway(K)(0.998426)-RIG-I-like receptor signaling pathway(K)(0.9639924)-Signaling by Aurora kinases(N)(0.9800438)-Signalling by NGF(R)(0.9958978)-TCR signaling in naive CD4+ T cells(N)(0.9790894)-TGFBR(C)(0.996866)-TNF receptor signaling pathway(N)(0.9669312)-VEGFR3 signaling in lymphatic endothelium(N)(0.8134468)-actions of nitric oxide in the heart(B)(0.9256838)-bone remodeling(B)(0.950403)-cdk regulation of dna replication(B)(0.9178734)-cell cycle: g2/m checkpoint(B)(0.904354)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.9364206)-p75(NTR)-mediated signaling(N)(0.9976286)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9846156)-role of ran in mitotic spindle regulation(B)(0.856666)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.8733596)-the igf-1 receptor and longevity(B)(0.8295158)-toll-like receptor pathway(B)(0.9819996)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.8826512) 92 TNFSF11 13q14.11 0 0 0 0 32 22 318 0.3756 0 0.266666666666667 Cytokine-cytokine receptor interaction(K)(0.9982042)-IL6-mediated signaling events(N)(0.9989066)-bone remodeling(B)(0.9934872) 93 HRAS 11p15.5 0 0 0 0 22 22 2199 0.3756 1 0.183333333333333 Axon guidance(K)(0.997996)-B cell receptor signaling pathway(K)(0.988317)-Cell surface interactions at the vascular wall(R)(0.9977122)-Chemokine signaling pathway(K)(0.9965494)-EGFR1(C)(0.9982216)-Endocytosis(K)(0.9984802)-Endothelins(N)(0.9898714)-Fc-epsilon receptor I signaling in mast cells(N)(0.943044)-Focal adhesion(K)(0.9974436)-Glypican pathway(N)(0.9079632)-GnRH signaling pathway(K)(0.884723)-IL2-mediated signaling events(N)(0.9490496)-Insulin signaling pathway(K)(0.9979232)-Integrin signalling pathway(P)(0.9972888)-Long-term depression(K)(0.962869)-MAPK signaling pathway(K)(0.994885)-Natural killer cell mediated cytotoxicity(K)(0.9984186)-Nectin adhesion pathway(N)(0.9864448)-Pathways in cancer(K)(0.998472)-Prostate cancer(K)(0.9938166)-Proteogylcan syndecan-mediated signaling events(N)(0.995042)-Regulation of actin cytoskeleton(K)(0.9957998)-Signaling by EGFR(R)(0.9905218)-Signaling by PDGF(R)(0.9153436)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.97886)-Signaling events regulated by Ret tyrosine kinase(N)(0.9744596)-Signalling by NGF(R)(0.9963544)-T cell activation(P)(0.987297)-T cell receptor signaling pathway(K)(0.8718346)-TRAIL signaling pathway(N)(0.992338)-Tight junction(K)(0.9980722)-a6b1 and a6b4 Integrin signaling(N)(0.930395)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9488978)-il-2 receptor beta chain in t cell activation(B)(0.991285)-integrin signaling pathway(B)(0.9919416)-map kinase inactivation of smrt corepressor(B)(0.9150716)-mets affect on macrophage differentiation(B)(0.9894368)-p38 mapk signaling pathway(B)(0.9827164)-p75(NTR)-mediated signaling(N)(0.9846406)-the igf-1 receptor and longevity(B)(0.9897344) 94 SMPD1 11p15.4 0 0 0 0 11 22 1673 0.3756 0 0.0916666666666667 IL2-mediated signaling events(N)(0.9977204)-Lysosome(K)(0.9978252)-Metabolic pathways(K)(0.9991396)-Sphingosine 1-phosphate (S1P) pathway(N)(0.986165)-TNF receptor signaling pathway(N)(0.9976012)-TRAIL signaling pathway(N)(0.9992634) 95 PAPSS2 10q23.2 1 0 0 4 76 21 1199 0.3843 0 0.666666666666667 Metabolic pathways(K)(0.9995354)-Purine metabolism(K)(0.9978244)-Selenoamino acid metabolism(K)(0.9967658)-Sulfur metabolism(K)(0.996604) 96 RPS6 9p22.1 0 0 1 0 43 21 1050 0.3843 0 0.366666666666667 Endothelins(N)(0.998329)-Glypican pathway(N)(0.9946952)-IFN-gamma pathway(N)(0.998258)-IL2-mediated signaling events(N)(0.9931966)-Influenza Life Cycle(R)(0.9981872)-Insulin signaling pathway(K)(0.998973)-Metabolism of proteins(R)(0.998267)-Ribosome(K)(0.9920476)-Signaling by Insulin receptor(R)(0.9833002)-TRAIL signaling pathway(N)(0.9970938)-mTOR signaling pathway(K)(0.9966598) 97 SMS 23p22.11 0 0 0 2 75 20 1210 0.3895 0 0.641666666666667 Glutathione metabolism(K)(0.9984128)-Metabolic pathways(K)(0.998686)-Metabolism of amino acids(R)(0.9978452) 98 ALAS2 23p11.21 0 0 0 3 72 20 1139 0.3895 0 0.625 Metabolic pathways(K)(0.9987024)-Porphyrin and chlorophyll metabolism(K)(0.998243) 99 TAF1 23q13.1 0 0 0 0 77 20 330 0.3895 0 0.641666666666667 Basal transcription factors(K)(0.9955718)-Formation and Maturation of mRNA Transcript(R)(0.9989058)-HIV Life Cycle(R)(0.9961654)-Regulation of retinoblastoma protein(N)(0.9968618)-Transcription(R)(0.997768)-hypoxia and p53 in the cardiovascular system(B)(0.9950066) 100 DIS3 13q22.1 0 0 0 1 34 19 59 0.3931 0 0.291666666666667 RNA degradation(K)(0.9997154) 101 DMD 23p21.1 0 0 1 12 67 19 232 0.3931 0 0.666666666666667 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9978202)-Dilated cardiomyopathy(K)(0.9969644)-Hypertrophic cardiomyopathy (HCM)(K)(0.9954628)-Muscle contraction(R)(0.9947232)-Viral myocarditis(K)(0.999401)-agrin in postsynaptic differentiation(B)(0.9977694) 102 ARR3 23q13.1 0 0 0 4 74 19 353 0.3931 0 0.65 Thromboxane A2 receptor signaling(N)(0.9989492)-Visual signal transduction: Cones(N)(0.9976506)-Wnt signaling pathway(P)(0.9984574) 103 POLD1 19q13.33 0 0 0 0 10 18 1407 0.3931 0 0.0833333333333333 Base excision repair(K)(0.994615)-DNA Repair(R)(0.9701542)-DNA Replication(R)(0.984056)-DNA replication(K)(0.8897872)-Homologous recombination(K)(0.9950486)-Metabolic pathways(K)(0.9983358)-Mismatch repair(K)(0.995652)-Nucleotide excision repair(K)(0.9971358)-Purine metabolism(K)(0.9988648)-S Phase(R)(0.9889534)-Telomere Maintenance(R)(0.9973864) 104 PRKDC 8q11.21 4 0 0 0 3 18 802 0.3931 0 0.0583333333333333 Androgen-mediated signaling(N)(0.9839466)-BARD1 signaling events(N)(0.9967144)-Cell cycle(K)(0.9967014)-DNA Repair(R)(0.9978956)-FAS signaling pathway (CD95)(N)(0.891293)-Glypican pathway(N)(0.9982076)-Non-homologous end-joining(K)(0.800951)-TRAIL signaling pathway(N)(0.9944372) 105 SNW1 14q24.3 0 0 0 0 24 18 366 0.3931 0 0.2 Generic Transcription Pathway(R)(0.9952328)-NOTCH(C)(0.998598)-Notch signaling pathway(K)(0.9921844)-Spliceosome(K)(0.9986844)-TGFBR(C)(0.9991292)-control of gene expression by vitamin d receptor(B)(0.991705) 106 ADCY6 12q13.12 0 1 0 1 7 18 1195 0.3931 0 0.075 Chemokine signaling pathway(K)(0.9965944)-Dilated cardiomyopathy(K)(0.8029772)-Endothelins(N)(0.9834434)-Gastric acid secretion(K)(0.8080368)-GnRH signaling pathway(K)(0.8163804)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.985339)-LPA receptor mediated events(N)(0.9658418)-Melanogenesis(K)(0.9877598)-Oocyte meiosis(K)(0.9979534)-Purine metabolism(K)(0.9993622)-Signalling by NGF(R)(0.9885886)-Vascular smooth muscle contraction(K)(0.9926044)-Vasopressin-regulated water reabsorption(K)(0.9964696) 107 CHRNA7 15q13.3 0 0 0 0 16 18 436 0.3931 0 0.133333333333333 Alzheimer disease-amyloid secretase pathway(P)(0.9983118)-Calcium signaling pathway(K)(0.9972006)-Neuroactive ligand-receptor interaction(K)(0.9985084) 108 WAS 23p11.23 0 0 0 1 77 18 634 0.3931 1 0.65 Adherens junction(K)(0.9942982)-Bacterial invasion of epithelial cells(K)(0.9976318)-Chemokine signaling pathway(K)(0.9988712)-Fc gamma R-mediated phagocytosis(K)(0.9984462)-Pathogenic Escherichia coli infection(K)(0.997191)-Regulation of actin cytoskeleton(K)(0.998085)-Shigellosis(K)(0.9917014)-T cell activation(P)(0.991682)-TCR signaling in naive CD4+ T cells(N)(0.9959144) 109 ARRB2 17p13.2 0 0 0 0 7 17 2176 0.3951 0 0.0583333333333333 Endocytosis(K)(0.9977772)-Glypican pathway(N)(0.9594232)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9643818)-IL1-mediated signaling events(N)(0.9620112)-IL12-mediated signaling events(N)(0.9409232)-IL4-mediated signaling events(N)(0.8058616)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.8324992)-MAPK signaling pathway(K)(0.995931)-Plasma membrane estrogen receptor signaling(N)(0.8930792)-Proteogylcan syndecan-mediated signaling events(N)(0.9964074)-Signaling by Aurora kinases(N)(0.9600628)-Signaling events mediated by the Hedgehog family(N)(0.996322)-TCR signaling in naive CD4+ T cells(N)(0.9672178)-TGFBR(C)(0.9957304)-TNF receptor signaling pathway(N)(0.8660636)-TRAIL signaling pathway(N)(0.9843612)-Wnt signaling pathway(P)(0.9984958)-Wnt(C)(0.998729)-p75(NTR)-mediated signaling(N)(0.9946298) 110 ALDH1B1 9p13.1 0 0 0 0 19 17 1183 0.3951 0 0.158333333333333 Fatty acid metabolism(K)(0.9956798)-Histidine metabolism(K)(0.9968422)-Lysine degradation(K)(0.9980866)-Metabolic pathways(K)(0.9992252)-Pyruvate metabolism(K)(0.9957378) 111 RENBP 23q28 0 0 0 5 78 17 45 0.3951 0 0.691666666666667 Amino sugar and nucleotide sugar metabolism(K)(0.9991284) 112 WEE1 11p15.4 0 0 0 0 11 17 283 0.3951 0 0.0916666666666667 Cell Cycle Checkpoints(R)(0.9963978)-Cell cycle(K)(0.9990454)-G1/S Transition(R)(0.9809528)-G2/M Transition(R)(0.997679) 113 DNAJA1 9p13.3 0 0 0 0 22 17 289 0.3951 0 0.183333333333333 Androgen-mediated signaling(N)(0.995467)-Protein processing in endoplasmic reticulum(K)(0.998473) 114 VTI1B 14q24.1 0 0 0 0 23 16 69 0.4067 0 0.191666666666667 Membrane Trafficking(R)(0.9987858)-SNARE interactions in vesicular transport(K)(0.9973958) 115 PLAU 10q22.2 0 0 0 0 79 16 396 0.4067 0 0.658333333333333 Complement and coagulation cascades(K)(0.9970176)-Integrins in angiogenesis(N)(0.998427)-Proteogylcan syndecan-mediated signaling events(N)(0.9995126)-amb2 Integrin signaling(N)(0.9980686)-fibrinolysis pathway(B)(0.839369) 116 HS6ST2 23q26.2 0 0 0 3 76 16 26 0.4067 0 0.658333333333333 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.998186) 117 AR 23q12 0 0 0 4 70 15 1028 0.4168 0 0.616666666666667 Alpha6Beta4Integrin(C)(0.995743)-Androgen-mediated signaling(N)(0.9686226)-AndrogenReceptor(C)(0.9958664)-FOXA transcription factor networks(N)(0.9851956)-Glypican pathway(N)(0.9983702)-IFN-gamma pathway(N)(0.9977566)-Oocyte meiosis(K)(0.9989406)-Pathways in cancer(K)(0.9976484)-Prostate cancer(K)(0.995666)-TGFBR(C)(0.9977644) 118 SEC61A1 3q21.3 0 0 0 0 5 15 382 0.4168 0 0.0416666666666667 Phagosome(K)(0.9966936)-Protein processing in endoplasmic reticulum(K)(0.9968668) 119 SCD 10q24.31 0 0 0 0 78 15 84 0.4168 0 0.65 Biosynthesis of unsaturated fatty acids(K)(0.9977244)-PPAR signaling pathway(K)(0.9975624) 120 NUPL1 13q12.13 0 0 0 0 21 15 429 0.4168 0 0.175 HIV Life Cycle(R)(0.9931638)-Host Interactions of HIV factors(R)(0.9994354)-Influenza Life Cycle(R)(0.9975952)-Metabolism of carbohydrates(R)(0.995833)-Metabolism of non-coding RNA(R)(0.9968616)-Transport of Mature Transcript to Cytoplasm(R)(0.993698) 121 UGT1A8 2q37.1 0 0 0 0 6 14 1192 0.4207 0 0.05 Drug metabolism - cytochrome P450(K)(0.99833)-Metabolic pathways(K)(0.9989284)-Porphyrin and chlorophyll metabolism(K)(0.9973014)-Retinol metabolism(K)(0.9889734)-Starch and sucrose metabolism(K)(0.9969492)-Steroid hormone biosynthesis(K)(0.9963158) 122 CHST7 23p11.3 0 0 0 1 78 14 22 0.4207 0 0.658333333333333 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9982772) 123 PSEN1 14q24.2 0 0 0 0 23 14 891 0.4207 0 0.191666666666667 Alzheimer disease-amyloid secretase pathway(P)(0.995564)-Alzheimer disease-presenilin pathway(P)(0.9990432)-Alzheimer's disease(K)(0.998868)-NOTCH(C)(0.9957614)-Neurotrophin signaling pathway(K)(0.9973532)-Notch signaling pathway(K)(0.993763)-Notch signaling pathway(P)(0.9342526)-Proteogylcan syndecan-mediated signaling events(N)(0.998732)-Signalling by NGF(R)(0.9969146)-Wnt signaling pathway(K)(0.9986988)-g-secretase mediated erbb4 signaling pathway(B)(0.987791)-p75(NTR)-mediated signaling(N)(0.9971072) 124 ACAT1 11q22.3 0 0 0 0 6 14 1292 0.4207 0 0.05 Fatty acid metabolism(K)(0.8772398)-Lysine degradation(K)(0.9988292)-Metabolic pathways(K)(0.9981664)-Metabolism of amino acids(R)(0.9966552)-Metabolism of lipids and lipoproteins(R)(0.9964568)-Pyruvate metabolism(K)(0.9765778)-Terpenoid backbone biosynthesis(K)(0.8735052) 125 AGTR2 23q23 0 0 0 6 68 14 488 0.4207 0 0.616666666666667 Class A/1 (Rhodopsin-like receptors)(R)(0.9978852)-Neuroactive ligand-receptor interaction(K)(0.9988024)-Receptor-ligand complexes bind G proteins(R)(0.999201)-Renin-angiotensin system(K)(0.99728)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9973722)-bioactive peptide induced signaling pathway(B)(0.996152)-chrebp regulation by carbohydrates and camp(B)(0.9943522)-ion channels and their functional role in vascular endothelium(B)(0.9978248)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.996886)-roles of ß arrestin dependent recruitment of src kinases in gpcr signaling(B)(0.9834382)-ß-arrestins in gpcr desensitization(B)(0.9462494) 126 BET1L 11p15.5 0 0 0 0 10 14 36 0.4207 0 0.0833333333333333 SNARE interactions in vesicular transport(K)(0.9993504) 127 GLUD1 10q23.2 0 0 0 0 80 13 1211 0.4286 0 0.666666666666667 Alanine, aspartate and glutamate metabolism(K)(0.994504)-Metabolic pathways(K)(0.9965126)-Metabolism of amino acids(R)(0.9979108)-Nitrogen metabolism(K)(0.9964168)-Proximal tubule bicarbonate reclamation(K)(0.9970558) 128 BMPR1A 10q23.2 0 1 0 0 79 13 816 0.4286 1 0.666666666666667 BMP receptor signaling(N)(0.998412)-Cytokine-cytokine receptor interaction(K)(0.997252)-TGF-beta signaling pathway(K)(0.9971486)-TGF-beta signaling pathway(P)(0.996686)-Wnt signaling pathway(P)(0.9985648) 129 CDKN1B 12p13.1 0 0 0 2 12 13 1217 0.4286 0 0.116666666666667 Cell cycle(K)(0.9980732)-DNA Replication(R)(0.9615558)-ErbB signaling pathway(K)(0.9946708)-FOXA transcription factor networks(N)(0.9752874)-FoxO family signaling(N)(0.9910022)-G1/S Transition(R)(0.9963008)-Glypican pathway(N)(0.9973686)-Integrins in angiogenesis(N)(0.9980264)-Interleukin signaling pathway(P)(0.9947218)-Pathways in cancer(K)(0.9975554)-Prostate cancer(K)(0.9151436)-Regulation of Telomerase(N)(0.998373)-Regulation of retinoblastoma protein(N)(0.9981762)-Signalling by NGF(R)(0.9986196)-TRAIL signaling pathway(N)(0.9974186) 130 CASP9 1p36.21 0 0 0 1 11 13 1435 0.4286 0 0.1 Amyotrophic lateral sclerosis (ALS)(K)(0.9936672)-Angiogenesis(P)(0.9919732)-Apoptosis(K)(0.9950204)-Apoptosis(R)(0.994926)-EGFR1(C)(0.9981006)-Glypican pathway(N)(0.9855942)-Huntington's disease(K)(0.9987192)-Parkinson's disease(K)(0.9987402)-Pathways in cancer(K)(0.9968828)-Prostate cancer(K)(0.8915804)-Signalling by NGF(R)(0.9907412)-TNF receptor signaling pathway(N)(0.9966528)-VEGF signaling pathway(K)(0.8773718)-Viral myocarditis(K)(0.9961988)-p53 signaling pathway(K)(0.9964202)-p75(NTR)-mediated signaling(N)(0.9951718) 131 CDKN2A 9p21.3 2 0 1 53 19 13 1031 0.4286 1 0.608333333333333 Androgen-mediated signaling(N)(0.982774)-Cell cycle(K)(0.9985372)-FOXM1 transcription factor network(N)(0.9951462)-Glioma(K)(0.9960088)-Glypican pathway(N)(0.9973864)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9991264)-Melanoma(K)(0.991541)-Pathways in cancer(K)(0.997892)-Regulation of retinoblastoma protein(N)(0.9979124)-TRAIL signaling pathway(N)(0.9917778)-cell cycle: g1/s check point(B)(0.9815422)-ctcf: first multivalent nuclear factor(B)(0.9940894)-p53 signaling pathway(K)(0.9987978)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9921762) 132 MARS 12q13.3 0 8 3 0 5 13 68 0.4286 0 0.133333333333333 Aminoacyl-tRNA biosynthesis(K)(0.9984002)-Selenoamino acid metabolism(K)(0.9770396)-tRNA Aminoacylation(R)(0.9973002) 133 VCL 10q22.2 0 0 0 0 82 12 698 0.4386 0 0.683333333333333 Adherens junction(K)(0.9968776)-Amoebiasis(K)(0.9983816)-Bacterial invasion of epithelial cells(K)(0.9931396)-Focal adhesion(K)(0.998093)-Further platelet releasate(R)(0.9938638)-Integrin signalling pathway(P)(0.997335)-Integrins in angiogenesis(N)(0.9981246)-Leukocyte transendothelial migration(K)(0.9987636)-Nectin adhesion pathway(N)(0.9628902)-Regulation of actin cytoskeleton(K)(0.9990154)-Shigellosis(K)(0.9888252)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9979158)-integrin signaling pathway(B)(0.9927646)-rho cell motility signaling pathway(B)(0.9889378) 134 NONO 23q13.1 0 0 0 0 77 12 14 0.4386 1 0.641666666666667 Circadian rhythm pathway(N)(0.9986248) 135 FOS 14q24.3 0 0 0 0 24 12 1881 0.4386 0 0.2 Androgen-mediated signaling(N)(0.9341808)-Angiogenesis(P)(0.9918732)-B cell receptor signaling pathway(K)(0.8330714)-BMP receptor signaling(N)(0.9932578)-Chagas disease(K)(0.9984454)-EGFR1(C)(0.9980408)-Endothelins(N)(0.9891176)-FOXA transcription factor networks(N)(0.9741074)-FOXM1 transcription factor network(N)(0.9956292)-Fc-epsilon receptor I signaling in mast cells(N)(0.9868364)-Glypican pathway(N)(0.8859796)-Huntington disease(P)(0.9985272)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.995607)-IFN-gamma pathway(N)(0.9943316)-IL1-mediated signaling events(N)(0.9701662)-IL2-mediated signaling events(N)(0.9934232)-IL6-mediated signaling events(N)(0.9911686)-Integrins in angiogenesis(N)(0.9980488)-Interleukin signaling pathway(P)(0.961498)-Leishmaniasis(K)(0.9920564)-MAPK signaling pathway(K)(0.998721)-Pathways in cancer(K)(0.9990088)-Presenilin action in Notch and Wnt signaling(N)(0.8894864)-Proteogylcan syndecan-mediated signaling events(N)(0.9977664)-Regulation of Telomerase(N)(0.9991416)-T cell receptor signaling pathway(K)(0.9895042)-TCR signaling in naive CD4+ T cells(N)(0.9907914)-TGF-beta signaling pathway(P)(0.9912372)-TGFBR(C)(0.998329)-TRAIL signaling pathway(N)(0.9905132)-Toll-like receptor signaling pathway(K)(0.9881734)-il-2 receptor beta chain in t cell activation(B)(0.9849468)-mets affect on macrophage differentiation(B)(0.9555746)-oxidative stress induced gene expression via nrf2(B)(0.9914008)-p75(NTR)-mediated signaling(N)(0.9964916)-repression of pain sensation by the transcriptional regulator dream(B)(0.9504126)-t cell receptor signaling pathway(B)(0.9793394)-toll-like receptor pathway(B)(0.9660776) 136 PRKG1 10q11.23 0 0 2 0 81 12 1348 0.4386 0 0.691666666666667 BMP receptor signaling(N)(0.9977384)-Endothelin signaling pathway(P)(0.986625)-Gap junction(K)(0.9983634)-Glypican pathway(N)(0.9897276)-IFN-gamma pathway(N)(0.998131)-IL1-mediated signaling events(N)(0.9944618)-Long-term depression(K)(0.9956226)-Olfactory transduction(K)(0.998125)-Plasma membrane estrogen receptor signaling(N)(0.9961348)-Salivary secretion(K)(0.9966242)-TNF receptor signaling pathway(N)(0.99858)-Thromboxane A2 receptor signaling(N)(0.9950024)-Vascular smooth muscle contraction(K)(0.99683)-actions of nitric oxide in the heart(B)(0.9938628)-ion channels and their functional role in vascular endothelium(B)(0.9911686) 137 ABCC2 10q24.2 0 0 0 0 79 12 44 0.4386 0 0.658333333333333 ABC transporters(K)(0.998536) 138 ITPR3 6p21.31 4 0 0 0 13 12 1177 0.4386 0 0.141666666666667 Alzheimer's disease(K)(0.9987138)-B cell activation(P)(0.9886108)-Calcium signaling pathway(K)(0.996112)-Endothelin signaling pathway(P)(0.9612018)-Gap junction(K)(0.9978106)-Gastric acid secretion(K)(0.9926208)-GnRH signaling pathway(K)(0.9921434)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9972578)-Long-term depression(K)(0.8815372)-Long-term potentiation(K)(0.944369)-Oocyte meiosis(K)(0.9932156)-Opioid Signalling(R)(0.9908204)-Pancreatic secretion(K)(0.9966134)-Phosphatidylinositol signaling system(K)(0.996492)-Salivary secretion(K)(0.997551)-Signalling by NGF(R)(0.9972672)-Taste transduction(K)(0.9934362)-Vascular smooth muscle contraction(K)(0.9968694)-Wnt signaling pathway(P)(0.9984418) 139 JAK2 9p24.1 0 0 8 1 38 11 1036 0.4615 1 0.391666666666667 Adipocytokine signaling pathway(K)(0.9985494)-Chemokine signaling pathway(K)(0.9979362)-EGFR1(C)(0.9978034)-Endothelins(N)(0.9947922)-IFN-gamma pathway(N)(0.9992094)-IL12-mediated signaling events(N)(0.9948016)-IL6-mediated signaling events(N)(0.9969512)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9983698)-Jak-STAT signaling pathway(K)(0.9987976)-KitReceptor(C)(0.8849584)-Leishmaniasis(K)(0.9950962)-NOTCH(C)(0.99724)-Signaling events mediated by PTP1B(N)(0.9934394)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8521724)-a4b1 and a4b7 Integrin signaling(N)(0.9546384)-role of erbb2 in signal transduction and oncology(B)(0.9433446) 140 NR1H3 11p11.2 0 0 0 0 9 11 150 0.4615 0 0.075 NR transcription pathway(R)(0.9992484)-PPAR signaling pathway(K)(0.9994614)-Retinoic acid receptors-mediated signaling(N)(0.9970618)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9521544) 141 PSMD10 23q22.3 0 0 0 5 70 11 382 0.4615 0 0.625 APC/C-mediated degradation of cell cycle proteins(R)(0.9952622)-Apoptosis(R)(0.997747)-Cell Cycle Checkpoints(R)(0.9976802)-G1/S Transition(R)(0.9982996)-Host Interactions of HIV factors(R)(0.9985708)-Metabolism of amino acids(R)(0.9990992)-S Phase(R)(0.9938736)-Signaling by Wnt(R)(0.9918468) 142 GTF2H1 11p15.1 0 0 0 0 8 10 387 0.4638 0 0.0666666666666667 AndrogenReceptor(C)(0.9990222)-DNA Repair(R)(0.9987574)-Formation and Maturation of mRNA Transcript(R)(0.9993188)-HIV Life Cycle(R)(0.997387)-Transcription(R)(0.9973062) 143 MTMR1 23q28 0 0 0 2 75 10 1131 0.4638 0 0.641666666666667 Fructose and mannose metabolism(K)(0.9985048)-Metabolic pathways(K)(0.9991698)-Riboflavin metabolism(K)(0.9982466) 144 SLC18A3 10q11.23 0 0 0 0 74 10 42 0.4638 0 0.616666666666667 Synaptic Transmission(R)(0.9978156) 145 GSTO1 10q25.1 0 0 0 0 81 10 157 0.4638 0 0.675 Biological oxidations(R)(0.9985848)-Drug metabolism - cytochrome P450(K)(0.9955518)-Glutathione metabolism(K)(0.9973804)-Metabolism of vitamins and cofactors(R)(0.9934756)-Metabolism of xenobiotics by cytochrome P450(K)(0.9914008) 146 GBF1 10q24.32 0 0 0 1 83 10 771 0.4638 0 0.7 Glypican pathway(N)(0.9056616)-Membrane Trafficking(R)(0.9984922)-Plasma membrane estrogen receptor signaling(N)(0.997099)-Proteogylcan syndecan-mediated signaling events(N)(0.9978736)-TRAIL signaling pathway(N)(0.9967074)-adp-ribosylation factor(B)(0.9984042)-thrombin signaling and protease-activated receptors(B)(0.9963578) 147 H2AFB1 23q28 0 0 0 2 77 10 139 0.4638 0 0.658333333333333 Systemic lupus erythematosus(K)(0.9981856) 148 DICER1 14q32.13 0 0 0 0 21 10 18 0.4638 1 0.175 Regulatory RNA pathways(R)(0.9981134) 149 VLDLR 9p24.2 1 0 0 0 31 10 46 0.4638 0 0.258333333333333 Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9986218)-Reelin signaling pathway(N)(0.9950028) 150 HHEX 10q23.33 0 0 0 0 79 10 25 0.4638 0 0.658333333333333 Maturity onset diabetes of the young(K)(0.999088) 151 SNRPD2 19q13.32 0 0 0 1 12 10 366 0.4638 0 0.108333333333333 Formation and Maturation of mRNA Transcript(R)(0.9961782)-Influenza Life Cycle(R)(0.9984426)-Metabolism of non-coding RNA(R)(0.9967252)-Spliceosome(K)(0.9982736) 152 CLDN2 23q22.3 0 0 0 6 69 10 298 0.4638 0 0.625 Cell adhesion molecules (CAMs)(K)(0.9993198)-Leukocyte transendothelial migration(K)(0.9983204)-Tight junction(K)(0.99898) 153 BRCA2 13q13.1 2 1 1 0 23 9 457 0.4776 1 0.225 DNA Repair(R)(0.999532)-FOXM1 transcription factor network(N)(0.9984348)-Homologous recombination(K)(0.9979994)-Pathways in cancer(K)(0.9984748)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9960764) 154 NDST2 10q22.2 0 0 0 0 79 9 1130 0.4776 0 0.658333333333333 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.997194)-Metabolic pathways(K)(0.9982882) 155 BDKRB2 14q32.2 0 0 0 0 20 9 906 0.4776 0 0.166666666666667 Calcium signaling pathway(K)(0.9988976)-Chagas disease(K)(0.9981912)-Class A/1 (Rhodopsin-like receptors)(R)(0.9984922)-Complement and coagulation cascades(K)(0.998191)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9971708)-Neuroactive ligand-receptor interaction(K)(0.997317)-Receptor-ligand complexes bind G proteins(R)(0.985209)-Regulation of actin cytoskeleton(K)(0.999)-actions of nitric oxide in the heart(B)(0.9916756)-corticosteroids and cardioprotection(B)(0.9926284) 156 GSK3B 3q13.33 0 0 0 0 5 9 2291 0.4776 0 0.0416666666666667 Electron Transport Chain(R)(0.9990902)-Focal adhesion(K)(0.8088692)-M/G1 Transition(R)(0.8657804)-Signalling by NGF(R)(0.866427)-TNF alpha/NF-kB(C)(0.992058)-Wnt(C)(0.965554)-p38 MAPK signaling pathway(N)(0.8819852) 157 ATG4A 23q22.3 0 0 0 5 70 9 35 0.4776 0 0.625 Regulation of autophagy(K)(0.9991462) 158 UBQLN3 11p15.4 0 0 0 0 13 9 167 0.4776 0 0.108333333333333 Protein processing in endoplasmic reticulum(K)(0.999536) 159 ARAF 23p11.23 0 0 0 1 75 9 1071 0.4776 0 0.633333333333333 Acute myeloid leukemia(K)(0.9832364)-B cell activation(P)(0.99584)-Bladder cancer(K)(0.9391724)-EGFR1(C)(0.9986432)-ErbB signaling pathway(K)(0.9968722)-Insulin signaling pathway(K)(0.9989084)-Integrin signalling pathway(P)(0.998369)-Long-term depression(K)(0.9953408)-Long-term potentiation(K)(0.9908972)-Natural killer cell mediated cytotoxicity(K)(0.998477)-Pathways in cancer(K)(0.9971302)-Progesterone-mediated oocyte maturation(K)(0.9950218)-Prostate cancer(K)(0.9976978)-Ras Pathway(P)(0.9941384)-Regulation of actin cytoskeleton(K)(0.9963808)-T cell activation(P)(0.9940084)-Vascular smooth muscle contraction(K)(0.9986028)-mapkinase signaling pathway(B)(0.9956126) 160 RRM1 11p15.4 0 0 0 0 11 9 1222 0.4776 0 0.0916666666666667 Glutathione metabolism(K)(0.9989704)-Metablism of nucleotides(R)(0.9914214)-Metabolic pathways(K)(0.9990148)-Purine metabolism(K)(0.9991846) 161 CLN5 13q22.3 0 0 0 1 33 9 121 0.4776 0 0.283333333333333 Lysosome(K)(0.9990676) 162 PRPS2 23p22.2 0 0 1 0 66 8 1241 0.4979 0 0.558333333333333 Metabolic pathways(K)(0.9982088)-Metabolism of carbohydrates(R)(0.99878)-Pentose phosphate pathway(K)(0.9735474)-Purine metabolism(K)(0.9987708) 163 EIF5 14q32.32 0 0 0 0 20 8 211 0.4979 0 0.166666666666667 Metabolism of proteins(R)(0.9989664)-eukaryotic protein translation(B)(0.8444928)-regulation of eif2(B)(0.9977206) 164 DYNC1H1 14q32.31 0 0 0 0 17 8 399 0.4979 0 0.141666666666667 G2/M Transition(R)(0.9960646)-Huntington disease(P)(0.9991918)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9967586)-Phagosome(K)(0.999274)-Vasopressin-regulated water reabsorption(K)(0.9981468) 165 IGF2 11p15.5 0 0 0 0 23 8 38 0.4979 0 0.191666666666667 Insulin/IGF pathway-protein kinase B signaling cascade(P)(0.9982266)-Regulation of IGF Activity by IGFBP(R)(0.999395) 166 EXOSC10 1p36.22 0 0 0 1 13 8 59 0.4979 0 0.116666666666667 RNA degradation(K)(0.9989736) 167 NFIB 9p22.3 0 0 1 0 40 8 207 0.4979 1 0.341666666666667 FOXA transcription factor networks(N)(0.9959402)-Transcription(R)(0.998887) 168 VIM 10p12.33 0 0 2 0 66 8 526 0.4979 0 0.566666666666667 Alpha6Beta4Integrin(C)(0.9947422)-Apoptosis(R)(0.9970348)-Muscle contraction(R)(0.998491)-TNF receptor signaling pathway(N)(0.997756)-TRAIL signaling pathway(N)(0.997753) 169 NUP43 6q25.1 0 0 0 0 19 8 512 0.4979 0 0.158333333333333 HIV Life Cycle(R)(0.9944114)-Host Interactions of HIV factors(R)(0.9960976)-Influenza Life Cycle(R)(0.9974212)-M Phase(R)(0.999217)-Metabolism of carbohydrates(R)(0.997073)-Metabolism of non-coding RNA(R)(0.9959288)-Transport of Mature Transcript to Cytoplasm(R)(0.9900842) 170 PRSS3 9p13.3 0 0 0 0 20 8 367 0.4979 0 0.166666666666667 Neuroactive ligand-receptor interaction(K)(0.9990202)-Pancreatic secretion(K)(0.998673) 171 B4GALT1 9p13.3 0 0 0 0 22 7 1131 0.5145 0 0.183333333333333 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.9895054)-Metabolic pathways(K)(0.9987724) 172 ATP1B4 23q24 0 0 0 4 75 7 287 0.5145 0 0.658333333333333 Aldosterone-regulated sodium reabsorption(K)(0.9978744)-Cardiac muscle contraction(K)(0.9984044)-Gastric acid secretion(K)(0.9971912)-Pancreatic secretion(K)(0.9997068)-Proximal tubule bicarbonate reclamation(K)(0.9975978)-Salivary secretion(K)(0.9986802) 173 GJB1 23q13.1 0 0 0 0 78 7 20 0.5145 0 0.65 Gap junction trafficking and regulation(R)(0.9981688) 174 DCLRE1C 10p13 0 0 2 0 66 7 48 0.5145 0 0.566666666666667 Non-homologous end-joining(K)(0.9957076)-Primary immunodeficiency(K)(0.9995934) 175 PSMA6 14q13.2 0 0 0 0 20 7 437 0.5145 0 0.166666666666667 APC/C-mediated degradation of cell cycle proteins(R)(0.9935052)-Apoptosis(R)(0.9977298)-Cell Cycle Checkpoints(R)(0.998096)-G1/S Transition(R)(0.9556476)-Host Interactions of HIV factors(R)(0.9996624)-Metabolism of amino acids(R)(0.9977742)-Parkinson disease(P)(0.9972874)-Proteasome(K)(0.987289)-S Phase(R)(0.9938532)-Signaling by Wnt(R)(0.9935628) 176 NFKBIA 14q13.2 0 0 0 0 21 7 1751 0.5145 0 0.175 Adipocytokine signaling pathway(K)(0.9963788)-Apoptosis signaling pathway(P)(0.9929114)-Apoptosis(K)(0.8895728)-B cell receptor signaling pathway(K)(0.9741074)-Chagas disease(K)(0.9834458)-Chemokine signaling pathway(K)(0.9970668)-Cytosolic DNA-sensing pathway(K)(0.9928414)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9991074)-Glioma(K)(0.923916)-Glypican pathway(N)(0.992962)-IL12-mediated signaling events(N)(0.9899352)-IL2-mediated signaling events(N)(0.9785402)-IL23-mediated signaling events(N)(0.9759388)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9957256)-Innate Immunity Signaling(R)(0.9923436)-Integrins in angiogenesis(N)(0.9934036)-Leishmaniasis(K)(0.9875114)-NOD-like receptor signaling pathway(K)(0.989006)-NOTCH(C)(0.9949992)-Pathways in cancer(K)(0.99824)-Prostate cancer(K)(0.9908142)-RIG-I-like receptor signaling pathway(K)(0.9890014)-Shigellosis(K)(0.9921404)-Signaling by Aurora kinases(N)(0.9714888)-Signaling events mediated by HDAC Class I(N)(0.9986132)-Signalling by NGF(R)(0.9968948)-T cell receptor signaling pathway(K)(0.995044)-TCR signaling in naive CD4+ T cells(N)(0.9831366)-TNF alpha/NF-kB(C)(0.9979854)-TNF receptor signaling pathway(N)(0.9854848)-Toll-like receptor signaling pathway(K)(0.9878532)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9941414)-p75(NTR)-mediated signaling(N)(0.9948846) 177 SIRT1 10q21.3 0 0 0 0 81 7 315 0.5145 0 0.675 Androgen-mediated signaling(N)(0.9936206)-FoxO family signaling(N)(0.9969562)-Regulation of retinoblastoma protein(N)(0.9984008)-Signaling events mediated by HDAC Class I(N)(0.9985958)-p53 pathway(P)(0.997687) 178 TLN1 9p13.3 0 0 1 0 21 7 552 0.5145 0 0.183333333333333 Focal adhesion(K)(0.998995)-Formation of Platelet plug(R)(0.9974742)-Further platelet releasate(R)(0.9975184)-Integrin cell surface interactions(R)(0.9967414)-Integrin signalling pathway(P)(0.9977174)-Integrins in angiogenesis(N)(0.9981938)-Nectin adhesion pathway(N)(0.9986458)-a4b1 and a4b7 Integrin signaling(N)(0.9513248)-amb2 Integrin signaling(N)(0.9986852)-integrin signaling pathway(B)(0.9836674)-rho cell motility signaling pathway(B)(0.994785) 179 NRBF2 10q21.2 0 0 0 0 80 7 30 0.5145 0 0.666666666666667 NR transcription pathway(R)(0.9976934) 180 LRRC4C 11p12 1 0 0 0 10 7 129 0.5145 0 0.0916666666666667 Axon guidance(K)(0.9983574) 181 SLC25A5 23q24 0 0 0 2 73 7 599 0.5145 0 0.625 Calcium signaling pathway(K)(0.9985614)-Glucose Regulation of Insulin Secretion(R)(0.998246)-Host Interactions of HIV factors(R)(0.9984318)-Huntington's disease(K)(0.9955968)-Metablism of nucleotides(R)(0.996056)-Parkinson's disease(K)(0.993848) 182 RGS10 10q26.11 0 0 0 0 81 7 190 0.5145 0 0.675 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9986104)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9982532) 183 DDX23 12q13.12 0 0 1 1 5 7 232 0.5145 0 0.0583333333333333 Formation and Maturation of mRNA Transcript(R)(0.9985456)-Spliceosome(K)(0.9985104) 184 PHYH 10p13 0 0 2 0 68 6 169 0.5185 0 0.583333333333333 Metabolism of lipids and lipoproteins(R)(0.999383)-Peroxisome(K)(0.9972968) 185 ARNTL 11p15.2 0 0 0 0 11 6 30 0.5185 0 0.0916666666666667 Circadian rhythm - mammal(K)(0.9941124)-Circadian rhythm pathway(N)(0.9982796) 186 LAMC3 9q34.13 0 0 0 1 24 6 665 0.5185 0 0.208333333333333 Amoebiasis(K)(0.9979314)-ECM-receptor interaction(K)(0.9616022)-Focal adhesion(K)(0.9960534)-Integrin cell surface interactions(R)(0.9983408)-Integrin signalling pathway(P)(0.9985334)-Pathways in cancer(K)(0.9994342)-a6b1 and a6b4 Integrin signaling(N)(0.9948554)-agrin in postsynaptic differentiation(B)(0.960729)-prion pathway(B)(0.9971816) 187 ZDHHC21 9p22.3 0 0 1 0 40 6 11 0.5185 0 0.341666666666667 Metabolism of nitric oxide(R)(0.998653) 188 MAPK1 22q11.22 0 0 0 0 20 6 2676 0.5185 0 0.166666666666667 Adherens junction(K)(0.9914238)-Aldosterone-regulated sodium reabsorption(K)(0.9781166)-Alzheimer disease-amyloid secretase pathway(P)(0.9784812)-Alzheimer's disease(K)(0.9977712)-AndrogenReceptor(C)(0.9972998)-Angiopoietin receptor Tie2-mediated signaling(N)(0.8778596)-Apoptosis signaling pathway(P)(0.983274)-Axon guidance(K)(0.9991216)-B cell receptor signaling pathway(K)(0.8644398)-BMP receptor signaling(N)(0.9837398)-Chagas disease(K)(0.9966642)-Chemokine signaling pathway(K)(0.9937864)-Dorso-ventral axis formation(K)(0.9790402)-EGFR1(C)(0.997321)-Endothelin signaling pathway(P)(0.842005)-Endothelins(N)(0.929454)-Fc gamma R-mediated phagocytosis(K)(0.9948654)-Focal adhesion(K)(0.9927604)-Gap junction(K)(0.9886526)-Glypican pathway(N)(0.8432208)-GnRH signaling pathway(K)(0.8115188)-Graft-versus-host disease(K)(0.8404724)-IFN-gamma pathway(N)(0.9294298)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9660136)-Insulin signaling pathway(K)(0.9946068)-Integrin signalling pathway(P)(0.9968762)-Integrins in angiogenesis(N)(0.9931944)-Long-term depression(K)(0.8016244)-Long-term potentiation(K)(0.9422226)-MAPK signaling pathway(K)(0.997065)-NOD-like receptor signaling pathway(K)(0.9826472)-NOTCH(C)(0.9970718)-Oocyte meiosis(K)(0.9976568)-Parkinson disease(P)(0.9964962)-Pathways in cancer(K)(0.9985684)-Prostate cancer(K)(0.9858566)-Proteogylcan syndecan-mediated signaling events(N)(0.9964502)-Regulation of Telomerase(N)(0.9899594)-Regulation of actin cytoskeleton(K)(0.9982508)-Shigellosis(K)(0.975329)-Signaling by EGFR(R)(0.975827)-Signaling events mediated by PRL(N)(0.9917308)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9179826)-Signalling by NGF(R)(0.9916702)-T cell receptor signaling pathway(K)(0.9921592)-TCR signaling in naive CD4+ T cells(N)(0.9834316)-TGF-beta signaling pathway(K)(0.9980414)-TRAIL signaling pathway(N)(0.9649596)-Toll-like receptor signaling pathway(K)(0.8974996)-Vascular smooth muscle contraction(K)(0.9935938)-classical complement pathway(B)(0.9210132)-il-10 anti-inflammatory signaling pathway(B)(0.9073236)-il-2 receptor beta chain in t cell activation(B)(0.8793612)-mTOR signaling pathway(K)(0.9854306)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9838552)-p75(NTR)-mediated signaling(N)(0.9917808) 189 ACAT2 6q25.3 0 0 0 0 14 6 1173 0.5185 0 0.116666666666667 Lysine degradation(K)(0.9983424)-Metabolic pathways(K)(0.998764)-Pyruvate metabolism(K)(0.9677148)-Terpenoid backbone biosynthesis(K)(0.9964436) 190 IFNB1 9p21.3 0 0 1 17 40 6 993 0.5185 0 0.483333333333333 Chagas disease(K)(0.9976024)-Cytokine-cytokine receptor interaction(K)(0.9988812)-Cytosolic DNA-sensing pathway(K)(0.9984178)-Glypican pathway(N)(0.995422)-IFN-gamma pathway(N)(0.9987386)-Jak-STAT signaling pathway(K)(0.9959766)-Natural killer cell mediated cytotoxicity(K)(0.9990468)-RIG-I-like receptor signaling pathway(K)(0.9978204)-Toll-like receptor signaling pathway(K)(0.9963406)-double stranded rna induced gene expression(B)(0.9916898)-signal transduction through il1r(B)(0.9973578)-the information processing pathway at the ifn beta enhancer(B)(0.9940258) 191 MED4 13q14.2 0 0 0 0 38 6 33 0.5185 0 0.316666666666667 Generic Transcription Pathway(R)(0.998641) 192 UBE2D1 10q21.1 0 0 0 0 75 6 553 0.5185 0 0.625 APC/C-mediated degradation of cell cycle proteins(R)(0.99316)-Cell Cycle Checkpoints(R)(0.9975924)-Protein processing in endoplasmic reticulum(K)(0.9991802)-Signaling by BMP(R)(0.9963822)-Signaling by TGF beta(R)(0.9436916)-TGFBR(C)(0.998469)-Ubiquitin mediated proteolysis(K)(0.997684)-fibrinolysis pathway(B)(0.994644)-hypoxia and p53 in the cardiovascular system(B)(0.9949338)-hypoxia-inducible factor in the cardivascular system(B)(0.98792)-regulation of transcriptional activity by pml(B)(0.989775)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9979062) 193 SRP9L1 10q23.32 0 0 0 0 79 6 24 0.5185 0 0.658333333333333 Protein export(K)(0.998645) 194 STX1A 7q11.23 0 0 1 0 5 6 282 0.5185 0 0.05 Glucose Regulation of Insulin Secretion(R)(0.9982092)-Insulin Synthesis and Secretion(R)(0.9643238)-SNARE interactions in vesicular transport(K)(0.9984744)-Synaptic Transmission(R)(0.9973326) 195 PIK3CB 3q22.3 0 0 1 0 1 6 1726 0.5185 0 0.0166666666666667 () 196 GABRA3 23q28 0 0 0 4 71 6 283 0.5185 0 0.625 Neuroactive ligand-receptor interaction(K)(0.9972158)-cardiac protection against ros(B)(0.9979166)-gamma-aminobutyric acid receptor life cycle pathway(B)(0.9966842) 197 PCYT1B 23p22.11 0 0 0 5 70 6 1136 0.5185 0 0.625 Glycerophospholipid metabolism(K)(0.9975934)-Metabolic pathways(K)(0.9986624) 198 DKK1 10q21.1 0 0 0 0 75 6 621 0.5185 0 0.625 Glypican pathway(N)(0.9937676)-Presenilin action in Notch and Wnt signaling(N)(0.9987506)-Wnt signaling pathway(K)(0.99879)-Wnt(C)(0.9982016)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9927252)-multi-step regulation of transcription by pitx2(B)(0.9969524)-segmentation clock(B)(0.9944126) 199 KALRN 3q21.1 1 0 0 0 5 6 654 0.5185 0 0.05 Huntington disease(P)(0.997107)-Plasma membrane estrogen receptor signaling(N)(0.9986828)-Proteogylcan syndecan-mediated signaling events(N)(0.9975554)-Signaling by Rho GTPases(R)(0.9986348) 200 KLHL9 9p21.3 0 0 1 26 38 6 223 0.5185 0 0.541666666666667 Signaling by Aurora kinases(N)(0.9890956)-Ubiquitin mediated proteolysis(K)(0.9985822) 201 EXOSC8 13q13.3 0 0 0 0 26 6 59 0.5185 0 0.216666666666667 RNA degradation(K)(0.9988346) 202 NDUFB4 3q13.33 0 0 0 0 4 6 1332 0.5185 0 0.0333333333333333 Huntington's disease(K)(0.9968208)-Metabolic pathways(K)(0.9983044) 203 FAR1 11p15.2 0 0 0 0 10 6 169 0.5185 0 0.0833333333333333 Metabolism of lipids and lipoproteins(R)(0.9983102)-Peroxisome(K)(0.9994184) 204 PARS2 1p32.3 0 0 0 0 4 6 41 0.5185 0 0.0333333333333333 Aminoacyl-tRNA biosynthesis(K)(0.9946454) 205 FLT3 13q12.2 1 3 6 0 19 6 620 0.5185 1 0.241666666666667 Cytokine-cytokine receptor interaction(K)(0.9987414)-Hematopoietic cell lineage(K)(0.999068)-Pathways in cancer(K)(0.9980186) 206 CASP7 10q25.3 0 0 0 0 81 5 795 0.5384 0 0.675 Alzheimer's disease(K)(0.9991734)-Apoptosis signaling pathway(P)(0.98985)-Apoptosis(K)(0.997241)-Apoptosis(R)(0.996937)-FAS signaling pathway (CD95)(N)(0.9948184)-FAS signaling pathway(P)(0.996128)-TNF alpha/NF-kB(C)(0.997403)-TNF receptor signaling pathway(N)(0.9982012)-TRAIL signaling pathway(N)(0.9879038)-a6b1 and a6b4 Integrin signaling(N)(0.9966386)-b cell survival pathway(B)(0.9938306)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9827844)-internal ribosome entry pathway(B)(0.9914822)-regulation of cell cycle progression by plk3(B)(0.9928754)-trefoil factors initiate mucosal healing(B)(0.993985) 207 THBS2 6q27 0 0 0 0 14 5 559 0.5384 0 0.116666666666667 ECM-receptor interaction(K)(0.9975942)-Focal adhesion(K)(0.9982044)-Formation of Platelet plug(R)(0.9987096)-Malaria(K)(0.9974262)-Phagosome(K)(0.998256)-Signaling by PDGF(R)(0.9980226)-TGF-beta signaling pathway(K)(0.9989502) 208 AKR1C4 10p15.1 0 0 2 0 70 5 1158 0.5384 0 0.6 Metabolic pathways(K)(0.998331)-Metabolism of xenobiotics by cytochrome P450(K)(0.9965988)-Primary bile acid biosynthesis(K)(0.9003462)-Steroid hormone biosynthesis(K)(0.9963272) 209 PIR 23p22.2 0 0 0 8 71 5 15 0.5384 0 0.658333333333333 y branching of actin filaments(B)(0.9984844) 210 NEU2 2q37.1 0 0 0 0 6 5 51 0.5384 0 0.05 Other glycan degradation(K)(0.9981786)-Sphingolipid metabolism(K)(0.9971682) 211 PVRL2 19q13.32 0 0 0 1 11 5 364 0.5384 0 0.1 Adherens junction(K)(0.9987516)-Cell adhesion molecules (CAMs)(K)(0.9983908)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9976236)-Nectin adhesion pathway(N)(0.997088) 212 COL11A1 1p21.1 1 0 0 0 6 5 374 0.5384 0 0.0583333333333333 Amoebiasis(K)(0.9967676)-ECM-receptor interaction(K)(0.9701176)-Focal adhesion(K)(0.9989506)-Integrin signalling pathway(P)(0.9990686) 213 CD80 3q13.33 0 0 0 0 4 5 613 0.5384 0 0.0333333333333333 () 214 TAP2 6p21.32 0 0 0 0 6 5 275 0.5384 0 0.05 ABC transporters(K)(0.9945662)-Antigen processing and presentation(K)(0.9975298)-Phagosome(K)(0.9988968)-Primary immunodeficiency(K)(0.9879418) 215 AGTR1 3q24 0 0 0 0 1 5 942 0.5384 0 0.00833333333333333 () 216 ITGA5 12q13.13 0 1 1 0 6 5 988 0.5384 0 0.0666666666666667 Cell surface interactions at the vascular wall(R)(0.9963672)-Hematopoietic cell lineage(K)(0.996199)-Hypertrophic cardiomyopathy (HCM)(K)(0.8850384)-Integrin signalling pathway(P)(0.9967586)-Phagosome(K)(0.9989122)-Proteogylcan syndecan-mediated signaling events(N)(0.9983864)-Regulation of actin cytoskeleton(K)(0.9979626)-Shigellosis(K)(0.8577196) 217 OR2S2 9p13.3 0 0 1 0 20 5 413 0.5384 0 0.175 Olfactory transduction(K)(0.9986248) 218 NOTCH1 9q34.3 1 0 0 1 21 5 376 0.5384 1 0.183333333333333 Alzheimer disease-presenilin pathway(P)(0.9985176)-Angiogenesis(P)(0.9994688)-Dorso-ventral axis formation(K)(0.995499)-Generic Transcription Pathway(R)(0.998159)-NOTCH(C)(0.9986418)-Presenilin action in Notch and Wnt signaling(N)(0.9908606)-Prion diseases(K)(0.9976484)-Regulation of beta-cell development(R)(0.9958346) 219 B3GAT3 11q12.3 0 0 0 0 8 5 1139 0.5384 0 0.0666666666666667 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9204436)-Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.8962736)-Metabolic pathways(K)(0.9992192) 220 PIGA 23p22.2 0 0 0 7 67 5 1304 0.5384 0 0.616666666666667 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis(K)(0.9769436)-Metabolic pathways(K)(0.9982714)-Metabolism of proteins(R)(0.9987672) 221 FUCA2 6q24.2 0 0 0 0 21 5 16 0.5384 0 0.175 Other glycan degradation(K)(0.9984534) 222 STX7 6q23.2 0 0 0 0 20 5 284 0.5384 0 0.166666666666667 Membrane Trafficking(R)(0.9980132)-Parkinson disease(P)(0.9975308)-Phagosome(K)(0.9991064)-SNARE interactions in vesicular transport(K)(0.9974468) 223 TALDO1 11p15.5 0 0 0 0 29 5 1181 0.5384 0 0.241666666666667 Metabolic pathways(K)(0.998925)-Metabolism of carbohydrates(R)(0.9976964)-Pentose phosphate pathway(K)(0.9388874) 224 MBD4 3q21.3 0 0 0 0 3 5 99 0.5384 0 0.025 () 225 MYH14 19q13.33 0 0 0 0 10 5 404 0.5384 0 0.0833333333333333 Nicotinic acetylcholine receptor signaling pathway(P)(0.9977838)-Regulation of actin cytoskeleton(K)(0.9995538)-Tight junction(K)(0.9977346)-Viral myocarditis(K)(0.9968298) 226 FTMT 5q23.1 0 0 0 0 3 5 43 0.5384 0 0.025 Porphyrin and chlorophyll metabolism(K)(0.9970404) 227 GALC 14q31.3 0 0 0 0 20 5 1218 0.5384 0 0.166666666666667 Lysosome(K)(0.9988552)-Metabolic pathways(K)(0.998172) 228 NUP205 7q33 0 0 3 0 1 5 429 0.5384 0 0.0333333333333333 HIV Life Cycle(R)(0.9959872)-Host Interactions of HIV factors(R)(0.9892846)-Metabolism of carbohydrates(R)(0.996763)-Metabolism of non-coding RNA(R)(0.9039146) 229 CREM 10p11.21 0 0 1 0 71 4 914 0.5686 0 0.6 BMP receptor signaling(N)(0.996055)-Endothelins(N)(0.9949036)-Glypican pathway(N)(0.998145)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.999205)-IFN-gamma pathway(N)(0.9987658)-IL1-mediated signaling events(N)(0.9955552)-Plasma membrane estrogen receptor signaling(N)(0.9988744)-TCR signaling in naive CD4+ T cells(N)(0.9955076)-TNF receptor signaling pathway(N)(0.9987876)-TRAIL signaling pathway(N)(0.9926178)-regulation of spermatogenesis by crem(B)(0.9923462) 230 DNA2 10q21.3 0 0 0 0 79 4 145 0.5686 0 0.658333333333333 DNA Replication(R)(0.9982472)-DNA replication(K)(0.9973444)-S Phase(R)(0.9987164)-Telomere Maintenance(R)(0.9991478) 231 ATM 11q22.3 1 0 0 0 7 4 1226 0.5686 1 0.0666666666666667 Apoptosis(K)(0.9960952)-BARD1 signaling events(N)(0.9959998)-Cell Cycle Checkpoints(R)(0.998732)-Cell cycle(K)(0.9978364)-DNA Repair(R)(0.9991888)-Glypican pathway(N)(0.9498632)-IFN-gamma pathway(N)(0.9965584)-IL12-mediated signaling events(N)(0.9919862)-IL2-mediated signaling events(N)(0.9823286)-LPA receptor mediated events(N)(0.9949264)-Regulation of Telomerase(N)(0.9946882)-Signaling by Aurora kinases(N)(0.9727246)-Signaling events regulated by Ret tyrosine kinase(N)(0.9831916)-TCR signaling in naive CD4+ T cells(N)(0.9706568)-TNF receptor signaling pathway(N)(0.9805394)-p53 pathway(P)(0.982637)-p53 signaling pathway(K)(0.9969382)-p75(NTR)-mediated signaling(N)(0.9943456) 232 NRP1 10p11.22 0 0 2 0 70 4 186 0.5686 0 0.6 Axon guidance(K)(0.9992516)-Signaling by VEGF(R)(0.953788)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9973906) 233 ACOT1 14q24.3 0 0 0 0 23 4 21 0.5686 0 0.191666666666667 Biosynthesis of unsaturated fatty acids(K)(0.9994834) 234 NCOR1 17p11.2 0 0 0 0 7 4 772 0.5686 0 0.0583333333333333 Glypican pathway(N)(0.9974282)-Huntington disease(P)(0.9974234)-IFN-gamma pathway(N)(0.9983916)-NOTCH(C)(0.9975744)-NR transcription pathway(R)(0.996756)-Signaling events mediated by HDAC Class I(N)(0.9978416)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9950432) 235 SMARCE1 17q21.2 0 0 0 0 5 4 440 0.5686 0 0.0416666666666667 Wnt signaling pathway(P)(0.99878)-control of gene expression by vitamin d receptor(B)(0.9517356)-the information processing pathway at the ifn beta enhancer(B)(0.983174) 236 CXCL12 10q11.21 0 0 0 0 66 4 1071 0.5686 0 0.55 Axon guidance(K)(0.9977302)-Chemokine signaling pathway(K)(0.9984628)-Class A/1 (Rhodopsin-like receptors)(R)(0.99771)-Cytokine-cytokine receptor interaction(K)(0.9985324)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9977276)-Intestinal immune network for IgA production(K)(0.9962102)-Leukocyte transendothelial migration(K)(0.998298)-Proteogylcan syndecan-mediated signaling events(N)(0.9986842)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9944772)-chrebp regulation by carbohydrates and camp(B)(0.9973162)-corticosteroids and cardioprotection(B)(0.996518)-ion channels and their functional role in vascular endothelium(B)(0.9958858)-ß-arrestins in gpcr desensitization(B)(0.967979) 237 RANGAP1 22q13.2 0 0 0 1 27 4 367 0.5686 0 0.233333333333333 HIV Life Cycle(R)(0.9973782)-Host Interactions of HIV factors(R)(0.998234)-M Phase(R)(0.9989532)-Signaling events mediated by HDAC Class I(N)(0.9977328)-role of ran in mitotic spindle regulation(B)(0.991471) 238 FANCG 9p13.3 0 0 1 0 19 4 36 0.5686 1 0.166666666666667 BARD1 signaling events(N)(0.9989316)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9918646) 239 POLL 10q24.32 0 0 0 0 84 4 46 0.5686 0 0.7 Base excision repair(K)(0.9986926)-Non-homologous end-joining(K)(0.998128) 240 BCAT2 19q13.33 0 0 0 1 14 4 1223 0.5686 0 0.125 Metabolic pathways(K)(0.9988998)-Metabolism of amino acids(R)(0.997568)-Pantothenate and CoA biosynthesis(K)(0.9271442)-Synaptic Transmission(R)(0.9968122)-Valine, leucine and isoleucine biosynthesis(K)(0.9885548) 241 ERBB3 12q13.2 1 0 1 0 7 4 815 0.5686 0 0.075 Calcium signaling pathway(K)(0.9976932)-EGF receptor signaling pathway(P)(0.9956924)-Endocytosis(K)(0.9985788)-a6b1 and a6b4 Integrin signaling(N)(0.9931318)-agrin in postsynaptic differentiation(B)(0.996971)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.9275546)-phosphoinositides and their downstream targets(B)(0.9930732)-y branching of actin filaments(B)(0.9953336) 242 SPIRE1 18p11.21 0 0 0 0 4 4 25 0.5686 0 0.0333333333333333 () 243 AMT 3p21.31 0 0 0 0 13 4 1142 0.5686 0 0.108333333333333 Metabolic pathways(K)(0.9990206)-Nitrogen metabolism(K)(0.9916022) 244 FUCA1 1p36.11 0 0 0 1 6 4 128 0.5686 0 0.0583333333333333 Lysosome(K)(0.9991138)-Other glycan degradation(K)(0.946727) 245 LPL 8p21.3 0 0 1 0 3 4 385 0.5686 0 0.0333333333333333 Alzheimer's disease(K)(0.9988694)-Glycerolipid metabolism(K)(0.9962922)-Metabolism of lipids and lipoproteins(R)(0.999091)-PPAR signaling pathway(K)(0.9930524) 246 RFXAP 13q13.3 0 0 0 0 26 4 104 0.5686 0 0.216666666666667 Antigen processing and presentation(K)(0.9984574)-Primary immunodeficiency(K)(0.999414) 247 ALG13 23q23 0 0 0 5 72 4 1123 0.5686 0 0.641666666666667 Metabolic pathways(K)(0.9986682)-N-Glycan biosynthesis(K)(0.8138578) 248 AQP3 9p13.3 0 0 0 0 23 4 44 0.5686 0 0.191666666666667 Vasopressin-regulated water reabsorption(K)(0.9976978) 249 RPS6KA3 23p22.12 1 0 0 7 68 4 764 0.5686 0 0.633333333333333 Androgen-mediated signaling(N)(0.9696384)-EGFR1(C)(0.998535)-Interleukin signaling pathway(P)(0.9953368)-Long-term potentiation(K)(0.9892426)-MAPK signaling pathway(K)(0.9984342)-Neurotrophin signaling pathway(K)(0.9956124)-Oocyte meiosis(K)(0.9971906)-Progesterone-mediated oocyte maturation(K)(0.992478)-Ras Pathway(P)(0.9943276)-Signalling by NGF(R)(0.9985844)-mTOR signaling pathway(K)(0.9984714) 250 SLC10A2 13q33.1 0 1 0 0 25 4 106 0.5686 0 0.216666666666667 Metabolism of lipids and lipoproteins(R)(0.9984818) 251 CNOT2 12q15 0 3 0 0 6 4 59 0.5686 0 0.075 RNA degradation(K)(0.998954) 252 NDUFB8 10q24.31 0 0 0 0 75 4 1332 0.5686 0 0.625 Alzheimer's disease(K)(0.997638)-Glucose Regulation of Insulin Secretion(R)(0.9966088)-Huntington's disease(K)(0.9987438)-Metabolic pathways(K)(0.9982352)-Oxidative phosphorylation(K)(0.997948)-Parkinson's disease(K)(0.9968174) 253 ISY1 3q21.3 0 0 0 0 3 4 128 0.5686 0 0.025 () 254 TRIM21 11p15.4 0 0 0 0 12 4 139 0.5686 0 0.1 Systemic lupus erythematosus(K)(0.9986624) 255 SMARCA2 9p24.3 0 0 0 0 31 4 413 0.5686 0 0.258333333333333 Androgen-mediated signaling(N)(0.993089)-Wnt signaling pathway(P)(0.9988194) 256 AVPR2 23q28 0 0 0 5 78 3 800 0.5813 0 0.691666666666667 Class A/1 (Rhodopsin-like receptors)(R)(0.994763)-Neuroactive ligand-receptor interaction(K)(0.9988816)-Plasma membrane estrogen receptor signaling(N)(0.997585)-Proteogylcan syndecan-mediated signaling events(N)(0.9977708)-Receptor-ligand complexes bind G proteins(R)(0.997286)-Vasopressin-regulated water reabsorption(K)(0.9969206) 257 POMT2 14q24.3 0 0 0 0 23 3 3 0.5813 0 0.191666666666667 () 258 RHOA 3p21.31 0 0 0 0 13 3 2226 0.5813 0 0.108333333333333 Adherens junction(K)(0.9941284)-Alpha6Beta4Integrin(C)(0.9924158)-Angiogenesis(P)(0.8617648)-Axon guidance(K)(0.9955506)-Chemokine signaling pathway(K)(0.9982122)-E-cadherin signaling in the nascent adherens junction(N)(0.858319)-Endocytosis(K)(0.9981818)-Focal adhesion(K)(0.8143046)-Glypican pathway(N)(0.9459912)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9696672)-Integrin signalling pathway(P)(0.9924368)-Integrins in angiogenesis(N)(0.9950792)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9749858)-Pancreatic secretion(K)(0.9929838)-Pathogenic Escherichia coli infection(K)(0.9880072)-Pathways in cancer(K)(0.9982086)-Proteogylcan syndecan-mediated signaling events(N)(0.9986456)-Regulation of actin cytoskeleton(K)(0.9982524)-Signaling by Aurora kinases(N)(0.97827)-Signaling by Rho GTPases(R)(0.9987206)-Signaling events mediated by PRL(N)(0.9904848)-Signalling by NGF(R)(0.9964782)-T cell receptor signaling pathway(K)(0.9952862)-TGF-beta signaling pathway(K)(0.9970206)-TRAIL signaling pathway(N)(0.944083)-Tight junction(K)(0.9987642)-Vascular smooth muscle contraction(K)(0.989701)-Wnt signaling pathway(K)(0.997054)-Wnt(C)(0.994354)-amb2 Integrin signaling(N)(0.987899)-p75(NTR)-mediated signaling(N)(0.9800334) 259 AK3 9p24.1 0 0 1 0 35 3 99 0.5813 0 0.3 Pyrimidine metabolism(K)(0.9970146) 260 ACTB 7p22.1 0 0 3 0 1 3 1304 0.5813 0 0.0333333333333333 Adherens junction(K)(0.9883784)-Alzheimer disease-presenilin pathway(P)(0.9987192)-Bacterial invasion of epithelial cells(K)(0.9010616)-Focal adhesion(K)(0.9982908)-Gastric acid secretion(K)(0.9956868)-Huntington disease(P)(0.9980538)-Hypertrophic cardiomyopathy (HCM)(K)(0.8509984)-Integrin signalling pathway(P)(0.9960866)-Leukocyte transendothelial migration(K)(0.9971064)-Metabolism of proteins(R)(0.9971242)-Nicotinic acetylcholine receptor signaling pathway(P)(0.985683)-Phagosome(K)(0.9979376)-Regulation of actin cytoskeleton(K)(0.997094)-Tight junction(K)(0.9989972)-Vibrio cholerae infection(K)(0.994364)-the information processing pathway at the ifn beta enhancer(B)(0.9293878) 261 CALM1 14q32.11 0 0 0 0 19 3 2001 0.5813 0 0.158333333333333 Alzheimer's disease(K)(0.999)-BMP receptor signaling(N)(0.9969592)-Calcium signaling pathway(K)(0.9987168)-Endothelins(N)(0.9745272)-Further platelet releasate(R)(0.9970958)-Gastric acid secretion(K)(0.9759006)-Glioma(K)(0.9590646)-Glypican pathway(N)(0.9979232)-GnRH signaling pathway(K)(0.882352)-IFN-gamma pathway(N)(0.9971102)-IL1-mediated signaling events(N)(0.9328772)-IL2-mediated signaling events(N)(0.9903022)-Insulin signaling pathway(K)(0.9954346)-Long-term potentiation(K)(0.9833244)-Melanogenesis(K)(0.9950144)-Metabolism of carbohydrates(R)(0.9979208)-Metabolism of nitric oxide(R)(0.989532)-Oocyte meiosis(K)(0.9969782)-Opioid Signalling(R)(0.9914136)-Phosphatidylinositol signaling system(K)(0.993774)-Plasma membrane estrogen receptor signaling(N)(0.9928498)-Salivary secretion(K)(0.9947412)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9945652)-Signalling by NGF(R)(0.9982954)-TCR signaling in naive CD4+ T cells(N)(0.9876124)-TNF receptor signaling pathway(N)(0.9686336)-TRAIL signaling pathway(N)(0.9827862)-Vascular smooth muscle contraction(K)(0.997349) 262 MDM2 12q15 1 11 0 1 5 3 1407 0.5813 1 0.15 Androgen-mediated signaling(N)(0.968796)-AndrogenReceptor(C)(0.9937572)-Cell Cycle Checkpoints(R)(0.9935094)-Cell cycle(K)(0.9975784)-Endocytosis(K)(0.9978156)-Glypican pathway(N)(0.9271976)-Pathways in cancer(K)(0.9985164)-Signalling by NGF(R)(0.997509)-TRAIL signaling pathway(N)(0.9977464)-Ubiquitin mediated proteolysis(K)(0.9989306)-ctcf: first multivalent nuclear factor(B)(0.9454788)-hypoxia and p53 in the cardiovascular system(B)(0.9413014)-p53 signaling pathway(K)(0.9949928)-sumoylation by ranbp2 regulates transcriptional repression(B)(0.960518) 263 PDSS1 10p12.1 0 0 2 0 75 3 15 0.5813 0 0.641666666666667 Terpenoid backbone biosynthesis(K)(0.9985696) 264 ESR1 6q25.1 0 0 0 0 17 3 1003 0.5813 0 0.141666666666667 AndrogenReceptor(C)(0.9966744)-BMP receptor signaling(N)(0.9966256)-FOXA transcription factor networks(N)(0.9665582)-FOXM1 transcription factor network(N)(0.9984286)-Glypican pathway(N)(0.995119)-IFN-gamma pathway(N)(0.9957912)-Plasma membrane estrogen receptor signaling(N)(0.9987822)-Regulation of Telomerase(N)(0.9977206)-Signaling events mediated by HDAC Class I(N)(0.9976106)-TGFBR(C)(0.9992454)-TNF receptor signaling pathway(N)(0.9956674)-downregulated of mta-3 in er-negative breast tumors(B)(0.9959104)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.993429) 265 ALPI 2q37.1 0 0 0 0 6 3 1121 0.5813 0 0.05 Metabolic pathways(K)(0.998214) 266 PRF1 10q22.1 1 0 0 0 81 3 635 0.5813 1 0.675 Autoimmune thyroid disease(K)(0.974023)-IL12-mediated signaling events(N)(0.998326)-IL2-mediated signaling events(N)(0.9973376)-Natural killer cell mediated cytotoxicity(K)(0.9975124)-TCR signaling in naive CD8+ T cells(N)(0.9972968)-TNF receptor signaling pathway(N)(0.9988078)-TRAIL signaling pathway(N)(0.9977068)-Type I diabetes mellitus(K)(0.9974952)-Viral myocarditis(K)(0.9975824)-granzyme a mediated apoptosis pathway(B)(0.9804996) 267 LAMA2 6q22.33 0 0 0 0 20 3 775 0.5813 0 0.166666666666667 Amoebiasis(K)(0.9994042)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9951194)-ECM-receptor interaction(K)(0.99625)-Focal adhesion(K)(0.9985306)-Hypertrophic cardiomyopathy (HCM)(K)(0.9700594)-Integrin cell surface interactions(R)(0.9965268)-Integrin signalling pathway(P)(0.9983824)-Pathways in cancer(K)(0.999397)-Viral myocarditis(K)(0.998963)-a6b1 and a6b4 Integrin signaling(N)(0.9946518)-agrin in postsynaptic differentiation(B)(0.9961214)-prion pathway(B)(0.9963766) 268 SNUPN 15q24.2 0 0 0 0 11 3 49 0.5813 0 0.0916666666666667 Metabolism of non-coding RNA(R)(0.9970728) 269 PREP 6q21 0 0 0 0 10 3 9 0.5813 0 0.0833333333333333 Vasopressin synthesis(P)(0.9987304) 270 CFP 23p11.23 0 0 0 1 75 3 10 0.5813 0 0.633333333333333 alternative complement pathway(B)(0.998377) 271 LDHA 11p15.1 2 0 0 0 8 3 1257 0.5813 0 0.0833333333333333 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9991878)-Metabolic pathways(K)(0.9990694)-Metabolism of carbohydrates(R)(0.999354)-Pyruvate metabolism(K)(0.9950318) 272 IGBP1 23q13.1 0 0 0 3 75 3 10 0.5813 0 0.65 p53 pathway by glucose deprivation(P)(0.9989272) 273 GNAT1 3p21.31 0 0 0 1 24 3 236 0.5813 0 0.208333333333333 Opioid Signalling(R)(0.9972988)-Receptor-ligand complexes bind G proteins(R)(0.9978356) 274 ALDH3A2 17p11.2 0 0 0 0 6 3 1184 0.5813 0 0.05 Lysine degradation(K)(0.9988218)-Metabolic pathways(K)(0.9989312)-Pyruvate metabolism(K)(0.9633038) 275 APBB1 11p15.4 0 0 0 0 11 3 313 0.5813 0 0.0916666666666667 Alzheimer disease-amyloid secretase pathway(P)(0.9980214)-Alzheimer disease-presenilin pathway(P)(0.9960288)-Alzheimer's disease(K)(0.9994022) 276 PTPLB 3q21.1 0 0 0 0 3 3 21 0.5813 0 0.025 Biosynthesis of unsaturated fatty acids(K)(0.9754032) 277 CCNE1 19q12 0 1 0 0 2 3 877 0.5813 1 0.025 Oocyte meiosis(K)(0.9981388)-Pathways in cancer(K)(0.9986242)-Signaling events mediated by PRL(N)(0.9208992)-TGFBR(C)(0.998489)-p53 pathway(P)(0.8093006) 278 MAD1L1 7p22.2 0 0 3 0 7 3 332 0.5813 0 0.0833333333333333 Cell Cycle Checkpoints(R)(0.9983116)-Cell cycle(K)(0.997723)-M Phase(R)(0.997913) 279 BECN1 17q21.31 0 0 0 0 3 3 35 0.5813 0 0.025 () 280 FDX1 11q22.3 0 0 0 0 7 3 13 0.5813 0 0.0583333333333333 () 281 CDKN2B 9p21.3 0 0 1 52 20 3 877 0.5813 0 0.608333333333333 Cell cycle(K)(0.998163)-Glypican pathway(N)(0.992398)-IFN-gamma pathway(N)(0.9994764)-Pathways in cancer(K)(0.998063)-Small cell lung cancer(K)(0.9586032)-TGF-beta signaling pathway(K)(0.9972986)-cell cycle: g1/s check point(B)(0.9924904) 282 PLXNB1 3p21.31 0 0 0 0 9 3 132 0.5813 0 0.075 Axon guidance(K)(0.9983452) 283 SMARCC1 3p21.31 0 0 0 0 7 3 440 0.5813 0 0.0583333333333333 Androgen-mediated signaling(N)(0.9883166)-Wnt signaling pathway(P)(0.9987056)-control of gene expression by vitamin d receptor(B)(0.9981748)-the information processing pathway at the ifn beta enhancer(B)(0.996359) 284 UBE2L3 22q11.21 0 0 0 1 22 3 455 0.5813 0 0.191666666666667 Alpha-synuclein signaling(N)(0.996887)-BARD1 signaling events(N)(0.9979244)-Parkinson disease(P)(0.9990078)-Parkinson's disease(K)(0.9969156)-TGFBR(C)(0.9987448)-Ubiquitin mediated proteolysis(K)(0.9988062) 285 GALT 9p13.3 0 0 2 0 20 3 1131 0.5813 0 0.183333333333333 Amino sugar and nucleotide sugar metabolism(K)(0.9980686)-Metabolic pathways(K)(0.9978006) 286 CHRDL1 23q22.3 0 0 0 5 74 3 225 0.5813 0 0.658333333333333 BMP receptor signaling(N)(0.998388)-Signaling by BMP(R)(0.998205) 287 GSTZ1 14q24.3 0 0 0 0 23 3 1173 0.5813 0 0.191666666666667 Drug metabolism - cytochrome P450(K)(0.9975932)-Glutathione metabolism(K)(0.995071)-Metabolic pathways(K)(0.9988906)-Metabolism of xenobiotics by cytochrome P450(K)(0.9953672)-Tyrosine metabolism(K)(0.991275) 288 SEH1L 18p11.21 0 0 0 0 3 3 512 0.5813 0 0.025 HIV Life Cycle(R)(0.8228196)-Host Interactions of HIV factors(R)(0.9973394)-Influenza Life Cycle(R)(0.9976892)-Metabolism of non-coding RNA(R)(0.9967866) 289 TNNT3 11p15.5 0 0 0 0 26 3 31 0.5813 0 0.216666666666667 Muscle contraction(R)(0.998059) 290 CTSD 11p15.5 0 0 0 0 26 3 574 0.5813 0 0.216666666666667 Lysosome(K)(0.9977122)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9758774)-TNF receptor signaling pathway(N)(0.9992444)-TRAIL signaling pathway(N)(0.997886)-downregulated of mta-3 in er-negative breast tumors(B)(0.996118) 291 CSGALNACT2 10q11.21 0 0 0 0 67 3 1129 0.5813 0 0.558333333333333 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.997821)-Metabolic pathways(K)(0.9991584) 292 PSMD1 2q37.1 0 0 0 0 3 3 501 0.5813 0 0.025 Apoptosis(R)(0.842138)-Cell Cycle Checkpoints(R)(0.9978674)-Host Interactions of HIV factors(R)(0.9976792)-TNF alpha/NF-kB(C)(0.9992232) 293 NT5C2 10q24.33 0 0 0 0 82 3 1196 0.5813 0 0.683333333333333 Metablism of nucleotides(R)(0.9965296)-Metabolic pathways(K)(0.9977774)-Nicotinate and nicotinamide metabolism(K)(0.8809514)-Purine metabolism(K)(0.9979292)-Pyrimidine metabolism(K)(0.8844614) 294 CUL1 7q36.1 0 0 2 0 2 3 983 0.5813 0 0.0333333333333333 Cell cycle(K)(0.999103)-Circadian rhythm - mammal(K)(0.8174726)-G1/S Transition(R)(0.9948102)-NOTCH(C)(0.9919154)-Oocyte meiosis(K)(0.9979736)-Parkinson disease(P)(0.9882342)-Protein processing in endoplasmic reticulum(K)(0.9979382)-TGF-beta signaling pathway(K)(0.9934174)-TGFBR(C)(0.9981028)-TNF alpha/NF-kB(C)(0.9972456)-Ubiquitin mediated proteolysis(K)(0.9949434)-Wnt signaling pathway(K)(0.9960368)-Wnt(C)(0.99364) 295 MLH3 14q24.3 0 0 0 0 24 3 23 0.5813 0 0.2 Mismatch repair(K)(0.9972762) 296 COX8C 14q32.13 0 0 0 0 22 3 1336 0.5813 0 0.183333333333333 Alzheimer's disease(K)(0.9973408)-Cardiac muscle contraction(K)(0.9982718)-Huntington's disease(K)(0.9992326)-Metabolic pathways(K)(0.9978892)-Oxidative phosphorylation(K)(0.9966202)-Parkinson's disease(K)(0.9958434) 297 PLOD2 3q24 0 0 0 0 2 3 44 0.5813 0 0.0166666666666667 () 298 AQP7 9p13.3 0 0 0 0 23 3 69 0.5813 0 0.191666666666667 PPAR signaling pathway(K)(0.9989594) 299 C1GALT1C1 23q24 0 0 0 4 74 3 1121 0.5813 0 0.65 Metabolic pathways(K)(0.9986382) 300 TEK 9p21.2 4 0 0 7 30 3 188 0.5813 0 0.333333333333333 Angiogenesis(P)(0.9992422)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9971822)-Cell surface interactions at the vascular wall(R)(0.9992544) 301 LSM6 4q31.22 0 0 1 0 1 3 180 0.5813 0 0.0166666666666667 RNA degradation(K)(0.9983848) 302 UPF3B 23q24 0 0 0 1 78 3 226 0.5813 0 0.658333333333333 Formation and Maturation of mRNA Transcript(R)(0.9983652)-Transcription(R)(0.9982752)-Transport of Mature Transcript to Cytoplasm(R)(0.9974156) 303 KPNA1 3q21.1 0 0 0 0 4 3 830 0.5813 0 0.0333333333333333 Ceramide signaling pathway(N)(0.8550632)-Host Interactions of HIV factors(R)(0.99702)-p38 MAPK signaling pathway(N)(0.9388482) 304 INHBA 7p14.1 0 0 5 0 1 3 374 0.5813 0 0.05 Cytokine-cytokine receptor interaction(K)(0.9951676)-TGF-beta signaling pathway(K)(0.9171882)-TGF-beta signaling pathway(P)(0.970547) 305 HPRT1 23q26.2 0 0 0 2 77 3 1192 0.5813 0 0.658333333333333 Drug metabolism - other enzymes(K)(0.9671318)-Metablism of nucleotides(R)(0.9975642)-Metabolic pathways(K)(0.9981952)-Purine metabolism(K)(0.9978246) 306 MAN1A1 6q22.31 1 0 0 1 15 2 1281 0.5934 0 0.133333333333333 Metabolic pathways(K)(0.9981828)-Protein processing in endoplasmic reticulum(K)(0.998703)-er associated degradation (erad) pathway(B)(0.9966362) 307 IRF7 11p15.5 0 0 0 0 22 2 656 0.5934 0 0.183333333333333 Cytosolic DNA-sensing pathway(K)(0.9971656)-Glypican pathway(N)(0.9986316)-IFN-gamma pathway(N)(0.9964066)-RIG-I-like receptor signaling pathway(K)(0.9975532)-Toll-like receptor signaling pathway(K)(0.9990028)-the information processing pathway at the ifn beta enhancer(B)(0.9957068) 308 GJA1 6q22.31 0 0 0 0 15 2 337 0.5934 0 0.125 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.999014)-EGFR1(C)(0.9981156)-Gap junction trafficking and regulation(R)(0.997616)-Gap junction(K)(0.9977992)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9972756) 309 PRKAR2B 7q22.3 0 0 5 0 1 2 705 0.5934 0 0.05 Apoptosis(K)(0.9863478)-G2/M Transition(R)(0.9934418)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9960794)-Signalling by NGF(R)(0.997613)-chrebp regulation by carbohydrates and camp(B)(0.9369034)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9401992) 310 DNTT 10q24.1 0 0 0 0 83 2 102 0.5934 0 0.691666666666667 Hematopoietic cell lineage(K)(0.9986802)-Non-homologous end-joining(K)(0.9986628) 311 SORBS1 10q23.33 0 0 0 0 87 2 608 0.5934 0 0.725 Adherens junction(K)(0.9988438)-Insulin signaling pathway(K)(0.9982576)-PPAR signaling pathway(K)(0.998235)-Plasma membrane estrogen receptor signaling(N)(0.998829)-Proteogylcan syndecan-mediated signaling events(N)(0.998285) 312 LIPA 10q23.31 0 0 0 2 83 2 137 0.5934 0 0.708333333333333 Lysosome(K)(0.9986634)-Steroid biosynthesis(K)(0.9980576) 313 SH3GL2 9p22.2 0 0 1 0 43 2 493 0.5934 0 0.366666666666667 EGFR1(C)(0.9981474)-Endocytosis(K)(0.9986552)-Membrane Trafficking(R)(0.9979408)-Signaling by EGFR(R)(0.9969566)-Signalling by NGF(R)(0.9983928) 314 MTMR2 11q21 0 0 0 0 6 2 1131 0.5934 0 0.05 Metabolic pathways(K)(0.9984098) 315 PIK3CD 1p36.22 0 0 0 1 21 2 1596 0.5934 0 0.183333333333333 Aldosterone-regulated sodium reabsorption(K)(0.990027)-Alpha6Beta4Integrin(C)(0.9855238)-Amoebiasis(K)(0.9958666)-Apoptosis(K)(0.99464)-B cell receptor signaling pathway(K)(0.9864612)-Bacterial invasion of epithelial cells(K)(0.9399628)-Chagas disease(K)(0.9946366)-Chemokine signaling pathway(K)(0.9964442)-EGFR1(C)(0.9972576)-Fc gamma R-mediated phagocytosis(K)(0.9979224)-Focal adhesion(K)(0.9965634)-Hypoxia response via HIF activation(P)(0.9722352)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9769166)-Inositol phosphate metabolism(K)(0.9662074)-Insulin signaling pathway(K)(0.9991664)-Integrin signalling pathway(P)(0.9987298)-Jak-STAT signaling pathway(K)(0.997856)-Leukocyte transendothelial migration(K)(0.9957638)-Natural killer cell mediated cytotoxicity(K)(0.997004)-Neurotrophin signaling pathway(K)(0.9975618)-Pathways in cancer(K)(0.9993132)-Phosphatidylinositol signaling system(K)(0.9991642)-Prostate cancer(K)(0.9609292)-Regulation of actin cytoskeleton(K)(0.9985912)-T cell activation(P)(0.987259)-T cell receptor signaling pathway(K)(0.9870584)-Toll-like receptor signaling pathway(K)(0.9941802)-Type II diabetes mellitus(K)(0.985928)-VEGF signaling pathway(K)(0.9255534)-mTOR signaling pathway(K)(0.9938466) 316 HEXB 5q13.3 0 0 0 0 2 2 1228 0.5934 0 0.0166666666666667 Lysosome(K)(0.9976466)-Metabolic pathways(K)(0.9980024) 317 DYNLT1 6q25.3 0 0 0 0 18 2 193 0.5934 0 0.15 Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9984598)-p75(NTR)-mediated signaling(N)(0.9974622) 318 BSG 19p13.3 0 0 0 0 17 2 503 0.5934 0 0.141666666666667 Cell surface interactions at the vascular wall(R)(0.9982714)-Integrin cell surface interactions(R)(0.9971406)-Metabolism of carbohydrates(R)(0.9989348)-Proteogylcan syndecan-mediated signaling events(N)(0.9985054)-Pyruvate metabolism and TCA cycle(R)(0.9704814) 319 BMPR1B 4q22.3 0 0 3 0 2 2 816 0.5934 0 0.0416666666666667 BMP receptor signaling(N)(0.9367546)-Cytokine-cytokine receptor interaction(K)(0.9985848)-TGF-beta signaling pathway(K)(0.997493)-Wnt signaling pathway(P)(0.99849) 320 NSF 17q21.32 0 0 0 0 17 2 55 0.5934 0 0.141666666666667 Vasopressin-regulated water reabsorption(K)(0.9985668) 321 B4GALT2 1p34.1 0 0 0 0 3 2 1131 0.5934 0 0.025 Metabolic pathways(K)(0.9992412) 322 POLR2A 17p13.1 0 0 0 0 11 2 1654 0.5934 0 0.0916666666666667 DNA Repair(R)(0.997622)-Formation and Maturation of mRNA Transcript(R)(0.9972936)-HIV Life Cycle(R)(0.9898312)-Huntington's disease(K)(0.9988294)-Influenza Life Cycle(R)(0.9993654)-Metabolic pathways(K)(0.998535)-Purine metabolism(K)(0.9986218)-Regulatory RNA pathways(R)(0.9830818)-Transcription(R)(0.997581)-telomeres telomerase cellular aging and immortality(B)(0.9941012) 323 THOP1 19p13.3 0 0 0 0 10 2 17 0.5934 0 0.0833333333333333 Renin-angiotensin system(K)(0.9967584) 324 PICALM 11q14.2 0 0 1 0 6 2 13 0.5934 1 0.0583333333333333 () 325 THBS1 15q14 2 0 0 0 17 2 841 0.5934 0 0.158333333333333 Bladder cancer(K)(0.9974328)-ECM-receptor interaction(K)(0.9955652)-Focal adhesion(K)(0.9981826)-Formation of Platelet plug(R)(0.9983092)-Integrin cell surface interactions(R)(0.9882574)-Malaria(K)(0.9952958)-Phagosome(K)(0.9987456)-Proteogylcan syndecan-mediated signaling events(N)(0.9984738)-Signaling by PDGF(R)(0.992212)-TGF-beta signaling pathway(K)(0.995823)-p53 pathway(P)(0.9970262)-p53 signaling pathway(K)(0.9989378) 326 NEGR1 1p31.1 0 0 0 0 7 2 135 0.5934 0 0.0583333333333333 Cell adhesion molecules (CAMs)(K)(0.997875) 327 NUP88 17p13.2 0 0 0 0 8 2 429 0.5934 0 0.0666666666666667 HIV Life Cycle(R)(0.993643)-Host Interactions of HIV factors(R)(0.9991372)-Influenza Life Cycle(R)(0.998533)-Metabolism of carbohydrates(R)(0.9975622)-Metabolism of non-coding RNA(R)(0.8342506)-Transport of Mature Transcript to Cytoplasm(R)(0.992186) 328 DUSP1 5q35.1 0 0 0 0 5 2 1052 0.5934 0 0.0416666666666667 BMP receptor signaling(N)(0.9971274)-EGFR1(C)(0.997803)-Fc-epsilon receptor I signaling in mast cells(N)(0.9921076)-Glypican pathway(N)(0.9989672)-IFN-gamma pathway(N)(0.979489)-IL1-mediated signaling events(N)(0.9780142)-MAPK signaling pathway(K)(0.9981908)-Plasma membrane estrogen receptor signaling(N)(0.8930276)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.995477) 329 ST3GAL1 8q24.22 0 0 1 0 3 2 1128 0.5934 0 0.0333333333333333 Metabolic pathways(K)(0.9976678) 330 HSP90AA1 NA 1 0 0 0 0 2 1669 0.5934 0 0.00833333333333333 () 331 PCK2 14q12 0 0 0 0 19 2 1382 0.5934 0 0.158333333333333 Adipocytokine signaling pathway(K)(0.9968634)-Insulin signaling pathway(K)(0.9988734)-Metabolic pathways(K)(0.9988352)-Metabolism of carbohydrates(R)(0.996648)-PPAR signaling pathway(K)(0.9984928)-Proximal tubule bicarbonate reclamation(K)(0.9982466)-Pyruvate metabolism(K)(0.9961836) 332 DLAT 11q23.1 0 0 0 0 7 2 1233 0.5934 0 0.0583333333333333 Metabolic pathways(K)(0.999013)-Metabolism of carbohydrates(R)(0.9980086)-Pyruvate metabolism(K)(0.9952402)-Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9912256) 333 GLA 23q22.1 0 0 0 1 76 2 231 0.5934 0 0.641666666666667 Galactose metabolism(K)(0.9982486)-Glycerolipid metabolism(K)(0.9963128)-Glycosphingolipid biosynthesis - globo series(K)(0.9898032)-Lysosome(K)(0.9991426)-Sphingolipid metabolism(K)(0.9978618) 334 SI 3q26.1 0 0 0 0 1 2 1183 0.5934 0 0.00833333333333333 Pyruvate metabolism(K)(0.9142066) 335 BCHE 3q26.1 0 0 0 0 1 2 42 0.5934 0 0.00833333333333333 () 336 UNC13B 9p13.3 0 0 1 0 21 2 47 0.5934 0 0.183333333333333 Synaptic Transmission(R)(0.9985918)-Synaptic_vesicle_trafficking(P)(0.9881244) 337 NT5C1A 1p34.2 0 0 0 0 2 2 1187 0.5934 0 0.0166666666666667 Metabolic pathways(K)(0.99869)-Purine metabolism(K)(0.974417) 338 CYP51A1 7q21.2 0 1 5 0 1 2 1207 0.5934 0 0.0583333333333333 Metabolic pathways(K)(0.998345)-Metabolism of lipids and lipoproteins(R)(0.9963132) 339 HEMK1 3p21.31 0 0 0 0 22 2 75 0.5934 0 0.183333333333333 Histidine metabolism(K)(0.9987844)-Selenoamino acid metabolism(K)(0.9977794)-Tyrosine metabolism(K)(0.9937368) 340 GZMA 5q11.2 0 0 0 0 2 2 392 0.5934 0 0.0166666666666667 Canonical NF-kappaB pathway(N)(0.8557516)-Neuroactive ligand-receptor interaction(K)(0.9454516) 341 NCOA1 2p23.3 0 0 1 0 4 2 804 0.5934 1 0.0416666666666667 Androgen-mediated signaling(N)(0.9865186)-Glypican pathway(N)(0.9960936)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9976472)-IFN-gamma pathway(N)(0.954649)-Retinoic acid receptors-mediated signaling(N)(0.9969686)-hypoxia-inducible factor in the cardivascular system(B)(0.9923564)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9944008)-tgf beta signaling pathway(B)(0.982149)-the information processing pathway at the ifn beta enhancer(B)(0.99843) 342 MTHFD1 14q23.2 0 0 0 0 21 2 1133 0.5934 0 0.175 Metabolic pathways(K)(0.9984528)-Metabolism of vitamins and cofactors(R)(0.9929646)-One carbon pool by folate(K)(0.9929294) 343 NR1I2 3q13.33 0 0 0 0 5 2 117 0.5934 0 0.0416666666666667 () 344 PFKP 10p15.2 0 0 2 0 65 2 1236 0.5934 0 0.558333333333333 Glucose Regulation of Insulin Secretion(R)(0.9987656)-Metabolic pathways(K)(0.9985424)-Metabolism of carbohydrates(R)(0.9973438)-Pentose phosphate pathway(K)(0.978403)-phosphoinositides and their downstream targets(B)(0.996151) 345 PAX2 10q24.31 0 0 0 0 76 2 108 0.5934 0 0.633333333333333 ID(C)(0.9979954)-Wnt(C)(0.9987462) 346 ADAM12 10q26.2 0 0 0 0 74 2 299 0.5934 0 0.616666666666667 Proteogylcan syndecan-mediated signaling events(N)(0.9987626)-Signaling by EGFR(R)(0.9975926)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9974564) 347 RAN 12q24.33 0 0 0 0 5 2 1216 0.5934 0 0.0416666666666667 HIV Life Cycle(R)(0.8530444)-Signaling events mediated by HDAC Class I(N)(0.9980256) 348 ETS1 11q24.3 0 0 1 0 7 2 974 0.5934 0 0.0666666666666667 Angiogenesis(P)(0.981216)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9956708)-Dorso-ventral axis formation(K)(0.9975286)-Glypican pathway(N)(0.9222482)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9002398)-IFN-gamma pathway(N)(0.9987994)-Pathways in cancer(K)(0.9971718)-TGFBR(C)(0.9987412)-TRAIL signaling pathway(N)(0.9985638) 349 MET 7q31.2 2 3 5 0 0 2 1344 0.5934 1 0.075 Adherens junction(K)(0.9980012)-Axon guidance(K)(0.9988384)-Bacterial invasion of epithelial cells(K)(0.9821198)-Cytokine-cytokine receptor interaction(K)(0.9988698)-Endocytosis(K)(0.9989594)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9925826)-FAS signaling pathway (CD95)(N)(0.9124276)-Focal adhesion(K)(0.9950522)-Malaria(K)(0.995707)-Pathways in cancer(K)(0.9989852)-Plasma membrane estrogen receptor signaling(N)(0.975288)-Proteogylcan syndecan-mediated signaling events(N)(0.9974946)-Regulation of retinoblastoma protein(N)(0.9948694)-a6b1 and a6b4 Integrin signaling(N)(0.8557162) 350 PTP4A3 8q24.3 0 0 0 0 15 2 22 0.5934 0 0.125 Signaling events mediated by PRL(N)(0.9990338) 351 CASP1 11q22.3 0 0 0 0 6 2 678 0.5934 0 0.05 Amyotrophic lateral sclerosis (ALS)(K)(0.9976248)-Cytosolic DNA-sensing pathway(K)(0.9697276)-IFN-gamma pathway(N)(0.9989934)-NOD-like receptor signaling pathway(K)(0.9981874)-TRAIL signaling pathway(N)(0.9992646) 352 XRCC3 14q32.33 0 0 0 0 20 2 28 0.5934 0 0.166666666666667 Homologous recombination(K)(0.9993586) 353 POLR2I 19q13.12 0 0 1 1 5 2 1635 0.5934 0 0.0583333333333333 DNA Repair(R)(0.9960996)-Formation and Maturation of mRNA Transcript(R)(0.9980468)-Huntington's disease(K)(0.9980216)-Influenza Life Cycle(R)(0.997469)-Metabolic pathways(K)(0.9972596)-Purine metabolism(K)(0.997701)-Regulatory RNA pathways(R)(0.8180146)-Transcription(R)(0.9946852) 354 CDK2 12q13.2 0 0 1 0 7 2 1135 0.5934 0 0.0666666666666667 Cell Cycle Checkpoints(R)(0.835382)-Cell cycle(K)(0.9341358)-FoxO family signaling(N)(0.9910266)-Glypican pathway(N)(0.9468308)-ID(C)(0.9360486)-Oocyte meiosis(K)(0.9960524)-Pathways in cancer(K)(0.9981022)-Prostate cancer(K)(0.9702704)-Signaling events mediated by PRL(N)(0.995705)-TGFBR(C)(0.989044)-p53 signaling pathway(K)(0.9980894) 355 NUP93 16q13 0 0 0 0 6 2 429 0.5934 0 0.05 HIV Life Cycle(R)(0.9952952)-Host Interactions of HIV factors(R)(0.9325812)-Metabolism of carbohydrates(R)(0.9972906) 356 NF1 17q11.2 16 0 0 2 6 2 571 0.5934 1 0.175 FOXA transcription factor networks(N)(0.98109)-MAPK signaling pathway(K)(0.9980598)-Proteogylcan syndecan-mediated signaling events(N)(0.9996864)-chromatin remodeling by hswi/snf atp-dependent complexes(B)(0.9986892) 357 DDX20 1p13.2 0 0 0 0 5 2 66 0.5934 0 0.0416666666666667 Metabolism of non-coding RNA(R)(0.99883)-mets affect on macrophage differentiation(B)(0.9323524) 358 NOTCH2 1p12 0 0 0 0 4 2 236 0.5934 1 0.0333333333333333 Alzheimer disease-presenilin pathway(P)(0.9988098)-Dorso-ventral axis formation(K)(0.99422)-Generic Transcription Pathway(R)(0.9962924)-NOTCH(C)(0.9978096) 359 HLA-E 6p21.33 2 0 0 0 0 2 720 0.5934 0 0.0166666666666667 () 360 PIWIL3 22q11.23 0 0 0 0 22 2 25 0.5934 0 0.183333333333333 Dorso-ventral axis formation(K)(0.9988594) 361 IMMP1L 11p13 0 1 1 0 7 2 24 0.5934 0 0.075 Protein export(K)(0.9989922) 362 ACOT7 1p36.31 0 0 0 1 22 2 21 0.5934 0 0.191666666666667 Biosynthesis of unsaturated fatty acids(K)(0.9989564) 363 ETV7 6p21.31 0 1 0 0 4 2 25 0.5934 0 0.0416666666666667 Dorso-ventral axis formation(K)(0.998382) 364 RAP1B 12q15 0 5 0 0 8 2 1461 0.5934 0 0.108333333333333 Chemokine signaling pathway(K)(0.9982742)-EphrinB-EPHB pathway(N)(0.8975686)-Formation of Platelet plug(R)(0.9987808)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9986604)-IFN-gamma pathway(N)(0.9956974)-Integrin signalling pathway(P)(0.9973702)-MAPK signaling pathway(K)(0.9979452)-Pancreatic secretion(K)(0.997454)-Proteogylcan syndecan-mediated signaling events(N)(0.9980264)-Renal cell carcinoma(K)(0.9524696)-amb2 Integrin signaling(N)(0.9916472)-p75(NTR)-mediated signaling(N)(0.9915036) 365 ZCCHC7 9p13.2 0 0 0 0 23 2 59 0.5934 0 0.191666666666667 RNA degradation(K)(0.9993516) 366 RNASEH2B 13q14.3 0 0 0 0 38 2 36 0.5934 0 0.316666666666667 DNA replication(K)(0.9993956) 367 LGMN 14q32.12 0 0 0 0 23 2 195 0.5934 0 0.191666666666667 Antigen processing and presentation(K)(0.9991866)-Lysosome(K)(0.9992592) 368 CP 3q25.1 0 0 1 0 1 2 120 0.5934 0 0.0166666666666667 () 369 CCNB3 23p11.22 0 0 0 3 76 2 228 0.5934 0 0.658333333333333 Cell cycle(K)(0.998558)-Progesterone-mediated oocyte maturation(K)(0.9977278)-p53 signaling pathway(K)(0.9993824) 370 ACCN1 17q12 0 0 0 0 7 2 52 0.5934 0 0.0583333333333333 () 371 NET1 10p15.1 0 0 2 0 74 2 125 0.5934 0 0.633333333333333 Signaling by Rho GTPases(R)(0.9989516) 372 RPL21 13q12.2 0 0 0 0 21 2 313 0.5934 0 0.175 Influenza Life Cycle(R)(0.998612)-Metabolism of proteins(R)(0.9993212)-Ribosome(K)(0.9967504) 373 FBXW4 10q24.32 0 0 0 0 86 2 201 0.5934 0 0.716666666666667 Metabolism of proteins(R)(0.9985362) 374 CD274 9p24.1 0 0 1 0 36 1 135 0.5934 1 0.308333333333333 Cell adhesion molecules (CAMs)(K)(0.9981048) 375 CSNK1E 22q13.1 0 0 0 1 33 1 569 0.5934 0 0.283333333333333 Circadian rhythm - mammal(K)(0.9947338)-Circadian rhythm pathway(N)(0.978578)-FoxO family signaling(N)(0.9959766)-G2/M Transition(R)(0.9987748)-Hedgehog signaling pathway(K)(0.9955602)-Signaling events mediated by the Hedgehog family(N)(0.9985586)-Wnt signaling pathway(K)(0.9987608)-Wnt signaling pathway(P)(0.999103)-Wnt(C)(0.9978364) 376 GBA3 4p15.31 0 0 1 0 3 1 59 0.5934 0 0.0333333333333333 () 377 DAO 12q24.11 0 0 0 0 3 1 1173 0.5934 0 0.025 Metabolic pathways(K)(0.9982134) 378 FPGS 9q34.11 0 0 0 0 10 1 1121 0.5934 0 0.0833333333333333 Metabolic pathways(K)(0.9981436) 379 MNAT1 14q23.1 0 0 0 0 20 1 574 0.5934 0 0.166666666666667 AndrogenReceptor(C)(0.9973054)-DNA Repair(R)(0.9955378)-Formation and Maturation of mRNA Transcript(R)(0.9974834)-G1 Phase(R)(0.9923156)-G1/S Transition(R)(0.9931566)-G2/M Transition(R)(0.9985218)-HIV Life Cycle(R)(0.9970964)-Nucleotide excision repair(K)(0.994208)-Retinoic acid receptors-mediated signaling(N)(0.9943436)-Transcription(R)(0.9984152) 380 GNA15 19p13.3 0 0 1 0 9 1 1194 0.5934 0 0.0833333333333333 Amoebiasis(K)(0.9968282)-Calcium signaling pathway(K)(0.998491)-Chagas disease(K)(0.9958704)-Endothelins(N)(0.9898722)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9971286)-Metabotropic glutamate receptor group I pathway(P)(0.977471)-Opioid Signalling(R)(0.9966168)-Proteogylcan syndecan-mediated signaling events(N)(0.9975232)-Receptor-ligand complexes bind G proteins(R)(0.9953232)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8677582)-Wnt signaling pathway(P)(0.9976146) 381 MYO9B 19p13.11 0 0 0 0 13 1 169 0.5934 0 0.108333333333333 Nicotinic acetylcholine receptor signaling pathway(P)(0.9976606)-Signaling by Rho GTPases(R)(0.9995468) 382 AGA 4q34.3 0 0 1 0 4 1 128 0.5934 0 0.0416666666666667 Lysosome(K)(0.9972356) 383 JUN 1p32.1 0 0 0 0 3 1 2127 0.5934 1 0.025 B cell activation(P)(0.8018948)-BMP receptor signaling(N)(0.8744126)-Chagas disease(K)(0.926227)-FAS signaling pathway(P)(0.8123084)-Huntington disease(P)(0.872108)-Leishmaniasis(K)(0.9978868)-MAPK signaling pathway(K)(0.9982596)-Pathways in cancer(K)(0.9937734)-Regulation of Telomerase(N)(0.9944066)-Signaling events regulated by Ret tyrosine kinase(N)(0.9806212)-T cell activation(P)(0.8980248)-TCR signaling in naive CD4+ T cells(N)(0.9785572)-TGFBR(C)(0.9972086)-TRAIL signaling pathway(N)(0.8887196)-Wnt signaling pathway(K)(0.9788816)-oxidative stress induced gene expression via nrf2(B)(0.9739824) 384 DLD 7q31.1 0 0 4 0 1 1 1298 0.5934 0 0.0416666666666667 Metabolic pathways(K)(0.9982488)-Metabolism of amino acids(R)(0.9977182)-Metabolism of carbohydrates(R)(0.9968764) 385 ADAM10 15q22.1 0 0 0 0 11 1 356 0.5934 0 0.0916666666666667 Alzheimer's disease(K)(0.9972524)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.997411)-Presenilin action in Notch and Wnt signaling(N)(0.9180162)-Signaling by EGFR(R)(0.9792756) 386 NOX4 11q14.3 0 1 0 0 6 1 51 0.5934 0 0.0583333333333333 Signaling events mediated by PTP1B(N)(0.9991674) 387 PRKCB 16p12.1 0 0 0 0 4 1 2397 0.5934 0 0.0333333333333333 Fc gamma R-mediated phagocytosis(K)(0.9178278)-Graft-versus-host disease(K)(0.8294852)-Pathogenic Escherichia coli infection(K)(0.9937946)-Presenilin action in Notch and Wnt signaling(N)(0.9022238)-TGFBR(C)(0.997652)-Thyroid cancer(K)(0.9609514)-integrin signaling pathway(B)(0.8476058) 388 GNAS NA 1 0 0 0 2 1 1504 0.5934 1 0.025 Amoebiasis(K)(0.9972724)-Calcium signaling pathway(K)(0.9990074)-Chagas disease(K)(0.9981714)-Gap junction(K)(0.993477)-Glypican pathway(N)(0.9550756)-Pancreatic secretion(K)(0.9531856)-Plasma membrane estrogen receptor signaling(N)(0.826127)-Proteogylcan syndecan-mediated signaling events(N)(0.997295)-Salivary secretion(K)(0.9673126)-Vascular smooth muscle contraction(K)(0.996635)-Vasopressin-regulated water reabsorption(K)(0.9977414)-Vibrio cholerae infection(K)(0.9944728) 389 TUBA1C 12q13.12 0 0 1 1 4 1 474 0.5934 0 0.05 Gap junction(K)(0.9976396)-Metabolism of proteins(R)(0.9994912)-Phagosome(K)(0.997481)-downregulated of mta-3 in er-negative breast tumors(B)(0.9956012) 390 LMNB1 5q23.2 0 0 0 0 3 1 484 0.5934 0 0.025 Apoptosis(R)(0.9984564)-FAS signaling pathway(P)(0.9883036)-TRAIL signaling pathway(N)(0.9709372) 391 SARS2 19q13.2 0 0 0 1 6 1 41 0.5934 0 0.0583333333333333 Aminoacyl-tRNA biosynthesis(K)(0.9976274) 392 STX4 16p11.2 0 0 0 0 15 1 594 0.5934 0 0.125 Formation of Platelet plug(R)(0.998999)-Membrane Trafficking(R)(0.999027)-Plasma membrane estrogen receptor signaling(N)(0.987295)-Proteogylcan syndecan-mediated signaling events(N)(0.9983236)-SNARE interactions in vesicular transport(K)(0.9952456)-Vasopressin-regulated water reabsorption(K)(0.9941398) 393 ILK 11p15.4 0 0 0 0 11 1 357 0.5934 0 0.0916666666666667 Bacterial invasion of epithelial cells(K)(0.9947388)-Endometrial cancer(K)(0.9981022)-Focal adhesion(K)(0.9980518)-Integrins in angiogenesis(N)(0.9969848)-PPAR signaling pathway(K)(0.998247) 394 EXT2 11p11.2 0 0 0 0 7 1 1130 0.5934 1 0.0583333333333333 Metabolic pathways(K)(0.9989748) 395 CHST6 16q23.1 0 0 0 0 7 1 15 0.5934 0 0.0583333333333333 () 396 GLI1 12q13.3 0 4 2 0 5 1 385 0.5934 0 0.0916666666666667 Pathways in cancer(K)(0.9983174)-Signaling events mediated by the Hedgehog family(N)(0.995653) 397 SAG 2q37.1 0 0 0 0 6 1 329 0.5934 0 0.05 Visual signal transduction: Rods(N)(0.9442522)-Wnt signaling pathway(P)(0.9978256) 398 PAX4 7q32.1 0 0 5 0 0 1 34 0.5934 0 0.0416666666666667 () 399 MYH6 14q11.2 0 0 0 0 17 1 632 0.5934 0 0.141666666666667 Cardiac muscle contraction(K)(0.9979482)-Dilated cardiomyopathy(K)(0.905227)-Hypertrophic cardiomyopathy (HCM)(K)(0.957938)-Muscle contraction(R)(0.9969646)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9938088)-Tight junction(K)(0.9977016)-Viral myocarditis(K)(0.9958066)-Wnt signaling pathway(P)(0.998865) 400 CD38 4p15.32 0 0 1 0 4 1 1441 0.5934 0 0.0416666666666667 Calcium signaling pathway(K)(0.9961806)-Hematopoietic cell lineage(K)(0.9961074)-Metabolic pathways(K)(0.998367)-Pancreatic secretion(K)(0.996884) 401 MTHFR 1p36.22 0 0 0 1 15 1 1124 0.5934 0 0.133333333333333 Metabolic pathways(K)(0.9993868) 402 ARHGAP9 12q13.3 0 6 2 0 5 1 125 0.5934 0 0.108333333333333 Signaling by Rho GTPases(R)(0.9984972) 403 SUOX 12q13.2 0 0 1 0 7 1 13 0.5934 0 0.0666666666666667 Sulfur metabolism(K)(0.959947) 404 TAS2R50 12p13.2 0 0 0 1 13 1 52 0.5934 0 0.116666666666667 Taste transduction(K)(0.991703) 405 CASP6 4q25 0 0 0 0 1 1 616 0.5934 0 0.00833333333333333 () 406 F7 13q34 0 0 0 0 19 1 272 0.5934 0 0.158333333333333 Complement and coagulation cascades(K)(0.9984906)-Metabolism of proteins(R)(0.998749) 407 RCC1 1p35.3 0 0 0 0 5 1 17 0.5934 0 0.0416666666666667 () 408 ARRB1 11q13.4 0 0 1 0 8 1 1284 0.5934 0 0.075 Chemokine signaling pathway(K)(0.9978112)-Endocytosis(K)(0.9985088)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9960106)-MAPK signaling pathway(K)(0.9988952)-Membrane Trafficking(R)(0.9968412)-Plasma membrane estrogen receptor signaling(N)(0.9983704)-Proteogylcan syndecan-mediated signaling events(N)(0.9957456)-Wnt signaling pathway(P)(0.9984284)-Wnt(C)(0.995473)-ß-arrestins in gpcr desensitization(B)(0.8978852) 409 CCND2 12p13.32 0 1 1 1 3 1 739 0.5934 1 0.05 Cell cycle(K)(0.9989794)-Focal adhesion(K)(0.995335)-IL2 signaling events mediated by PI3K(N)(0.940585)-Regulation of retinoblastoma protein(N)(0.8290236)-Wnt signaling pathway(K)(0.998572)-multi-step regulation of transcription by pitx2(B)(0.9616086)-p53 signaling pathway(K)(0.9956872) 410 GLS2 12q13.2 0 0 1 0 6 1 1211 0.5934 0 0.0583333333333333 Metabolic pathways(K)(0.998615)-Metabolism of amino acids(R)(0.9987722)-Nitrogen metabolism(K)(0.906248)-Proximal tubule bicarbonate reclamation(K)(0.8504838) 411 CHSY3 5q23.3 0 0 0 0 3 1 1129 0.5934 0 0.025 Metabolic pathways(K)(0.9990052) 412 CNOT4 7q33 0 0 3 0 1 1 59 0.5934 0 0.0333333333333333 RNA degradation(K)(0.9971054) 413 PTF1A 10p12.2 0 0 2 0 73 1 31 0.5934 0 0.625 Regulation of beta-cell development(R)(0.9989578) 414 SPCS3 4q34.2 0 0 2 0 4 1 61 0.5934 0 0.05 Insulin Synthesis and Secretion(R)(0.9986618) 415 GUCY2F 23q22.3 0 0 0 4 75 1 222 0.5934 0 0.658333333333333 Phototransduction(K)(0.9988682)-Purine metabolism(K)(0.998254)-Visual signal transduction: Cones(N)(0.9985336)-actions of nitric oxide in the heart(B)(0.9975284) 416 TUBA3C 13q12.11 0 0 0 0 18 1 474 0.5934 0 0.15 Gap junction(K)(0.9987952)-Metabolism of proteins(R)(0.9984436)-Pathogenic Escherichia coli infection(K)(0.9976606)-Phagosome(K)(0.9979926)-downregulated of mta-3 in er-negative breast tumors(B)(0.9984242)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9855794) 417 HMGB2 4q34.1 0 0 1 0 5 1 12 0.5934 0 0.05 granzyme a mediated apoptosis pathway(B)(0.9778498) 418 MAX 14q23.3 0 0 0 0 23 1 957 0.5934 0 0.191666666666667 Glypican pathway(N)(0.9951958)-IFN-gamma pathway(N)(0.9953124)-MAPK signaling pathway(K)(0.998786)-Pathways in cancer(K)(0.9977762)-Regulation of Telomerase(N)(0.996781)-Signaling events mediated by HDAC Class I(N)(0.9985614)-Small cell lung cancer(K)(0.9531964)-p38 mapk signaling pathway(B)(0.9941632) 419 VAMP3 1p36.23 0 0 0 1 16 1 612 0.5934 0 0.141666666666667 Beta1 adrenergic receptor signaling pathway(P)(0.9442476)-Phagosome(K)(0.9984872)-Plasma membrane estrogen receptor signaling(N)(0.9988318)-Proteogylcan syndecan-mediated signaling events(N)(0.9989676)-SNARE interactions in vesicular transport(K)(0.8962408) 420 PGK1 23q21.1 0 0 0 5 70 1 1284 0.5934 0 0.625 Glucose Regulation of Insulin Secretion(R)(0.9973682)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9979028)-Metabolic pathways(K)(0.999269)-Metabolism of carbohydrates(R)(0.9991758) 421 GNG3 11q12.3 0 0 0 0 7 1 804 0.5934 0 0.0583333333333333 Chemokine signaling pathway(K)(0.9964768)-Formation of Platelet plug(R)(0.9990648)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9989364)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.907959)-Opioid Signalling(R)(0.9909502)-Receptor-ligand complexes bind G proteins(R)(0.9962208)-Wnt signaling pathway(P)(0.9995684) 422 XRCC2 7q36.1 0 0 3 0 1 1 28 0.5934 0 0.0333333333333333 Homologous recombination(K)(0.9988254) 423 ADCY5 3q21.1 0 0 0 0 3 1 1042 0.5934 0 0.025 Gap junction(K)(0.9884016) 424 TK2 16q21 0 0 0 0 6 1 1235 0.5934 0 0.05 G1/S Transition(R)(0.9981774)-Metabolic pathways(K)(0.9993584) 425 NOS3 7q36.1 2 0 3 0 1 1 1743 0.5934 0 0.0416666666666667 Angiogenesis(P)(0.9970962)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9781858)-Calcium signaling pathway(K)(0.9980566)-Metabolic pathways(K)(0.999249)-Plasma membrane estrogen receptor signaling(N)(0.9735522)-Thromboxane A2 receptor signaling(N)(0.9937564)-VEGF signaling pathway(K)(0.9916856) 426 CA5B 23p22.2 0 0 0 7 71 1 23 0.5934 0 0.65 Nitrogen metabolism(K)(0.9985984) 427 PTPRN 2q35 0 0 0 0 1 1 45 0.5934 0 0.00833333333333333 () 428 GTF2A1 14q31.1 0 0 0 0 20 1 288 0.5934 0 0.166666666666667 Basal transcription factors(K)(0.9943918)-Formation and Maturation of mRNA Transcript(R)(0.9989888)-HIV Life Cycle(R)(0.9984518)-Transcription(R)(0.9978376)-carm1 and regulation of the estrogen receptor(B)(0.990499)-nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells(B)(0.9916678)-the information processing pathway at the ifn beta enhancer(B)(0.9967768) 429 DIAPH1 5q31.3 0 0 0 0 4 1 438 0.5934 0 0.0333333333333333 Focal adhesion(K)(0.9988252)-Nectin adhesion pathway(N)(0.9727922)-Shigellosis(K)(0.9113816) 430 PLD2 17p13.2 0 0 0 0 6 1 2170 0.5934 0 0.05 Angiopoietin receptor Tie2-mediated signaling(N)(0.9911498)-EGFR1(C)(0.9971354)-Endocytosis(K)(0.9993078)-Fc gamma R-mediated phagocytosis(K)(0.9965006)-Fc-epsilon receptor I signaling in mast cells(N)(0.9929308)-Glypican pathway(N)(0.9329432)-GnRH signaling pathway(K)(0.9368692)-Metabolic pathways(K)(0.9992162)-Parkinson disease(P)(0.9973518)-Plasma membrane estrogen receptor signaling(N)(0.9815662)-Proteogylcan syndecan-mediated signaling events(N)(0.9965902)-TRAIL signaling pathway(N)(0.997546) 431 PRKACB 1p31.1 0 0 0 0 8 1 1927 0.5934 0 0.0666666666666667 Amoebiasis(K)(0.9971984)-Apoptosis(K)(0.9906068)-Calcium signaling pathway(K)(0.9976582)-Chemokine signaling pathway(K)(0.9968042)-Hedgehog signaling pathway(K)(0.9930602)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.8777604)-Insulin signaling pathway(K)(0.994729)-MAPK signaling pathway(K)(0.999216)-Metabolism of lipids and lipoproteins(R)(0.9979938)-Prion diseases(K)(0.9907978)-Salivary secretion(K)(0.8082334)-Signalling by NGF(R)(0.9949128)-Vascular smooth muscle contraction(K)(0.9576978)-Vasopressin-regulated water reabsorption(K)(0.9969258)-Vibrio cholerae infection(K)(0.9719246)-Wnt signaling pathway(K)(0.9971074)-p75(NTR)-mediated signaling(N)(0.9994182) 432 GOT1 10q24.2 0 0 0 0 77 1 1252 0.5934 0 0.641666666666667 Alanine, aspartate and glutamate metabolism(K)(0.995423)-Metabolic pathways(K)(0.997201)-Metabolism of amino acids(R)(0.9986762)-Metabolism of carbohydrates(R)(0.996784)-Tyrosine metabolism(K)(0.9569738) 433 PDK2 17q21.33 1 0 0 0 13 1 59 0.5934 0 0.116666666666667 Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9967022)-mtor signaling pathway(B)(0.9853448)-pten dependent cell cycle arrest and apoptosis(B)(0.9978054)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9944746) 434 RDH12 14q24.1 0 0 0 0 21 1 1130 0.5934 0 0.175 Metabolic pathways(K)(0.9975304) 435 ABCC8 11p15.1 0 0 0 0 8 1 292 0.5934 0 0.0666666666666667 ABC transporters(K)(0.9964668)-FOXA transcription factor networks(N)(0.9872504)-Glucose Regulation of Insulin Secretion(R)(0.9976528)-Type II diabetes mellitus(K)(0.9907198) 436 AP2M1 3q27.1 0 1 1 0 0 1 1138 0.5934 0 0.0166666666666667 Endocytosis(K)(0.9977336)-Host Interactions of HIV factors(R)(0.9989134)-Huntington's disease(K)(0.9974318)-Syndecan-1-mediated signaling events(N)(0.8207138) 437 EPO 7q22.1 0 0 2 0 7 1 521 0.5934 0 0.075 Cytokine-cytokine receptor interaction(K)(0.998384)-Hematopoietic cell lineage(K)(0.9968742)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9987658)-Jak-STAT signaling pathway(K)(0.9974382)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9739884) 438 NRG2 5q31.3 0 0 0 0 3 1 121 0.5934 0 0.025 ErbB signaling pathway(K)(0.9970424)-agrin in postsynaptic differentiation(B)(0.9967834) 439 APEX1 14q11.2 0 0 0 0 15 1 110 0.5934 0 0.125 Base excision repair(K)(0.9972552)-DNA Repair(R)(0.998057) 440 TLR2 4q31.3 0 0 1 0 2 1 472 0.5934 0 0.025 Amoebiasis(K)(0.9986624)-Malaria(K)(0.988126)-Toll-like receptor signaling pathway(K)(0.9961998) 441 COL4A5 23q22.3 0 0 0 6 68 1 266 0.5934 0 0.616666666666667 Integrin cell surface interactions(R)(0.9988446)-Integrin signalling pathway(P)(0.9991978)-Signaling by PDGF(R)(0.9977488)-intrinsic prothrombin activation pathway(B)(0.9978936)-regulators of bone mineralization(B)(0.9544356) 442 KPNA2 17q24.2 1 0 0 0 2 1 842 0.5934 0 0.025 BMP receptor signaling(N)(0.9587684)-Endothelins(N)(0.9151738)-Glypican pathway(N)(0.8825698)-IL1-mediated signaling events(N)(0.8618226)-Plasma membrane estrogen receptor signaling(N)(0.9824236)-TNF alpha/NF-kB(C)(0.9989828)-TNF receptor signaling pathway(N)(0.8718402) 443 CSF2 5q31.1 0 0 0 0 4 1 1299 0.5934 0 0.0333333333333333 Amoebiasis(K)(0.8711848)-Cytokine-cytokine receptor interaction(K)(0.9990698)-Glypican pathway(N)(0.9593844)-IFN-gamma pathway(N)(0.9870074)-Jak-STAT signaling pathway(K)(0.800579)-Natural killer cell mediated cytotoxicity(K)(0.9514386)-Proteogylcan syndecan-mediated signaling events(N)(0.9985342)-Regulation of retinoblastoma protein(N)(0.998176)-TNF receptor signaling pathway(N)(0.9735082) 444 INSR 19p13.2 1 0 0 0 6 1 957 0.5934 0 0.0583333333333333 Adherens junction(K)(0.9985948)-Endothelins(N)(0.8573628)-Glypican pathway(N)(0.970455)-Insulin signaling pathway(K)(0.9985936)-Proteogylcan syndecan-mediated signaling events(N)(0.9979052)-Signaling events mediated by PTP1B(N)(0.9966148)-TRAIL signaling pathway(N)(0.9975436) 445 SLC2A4 17p13.1 0 0 0 0 11 1 637 0.5934 0 0.0916666666666667 Adipocytokine signaling pathway(K)(0.997841)-Insulin signaling pathway(K)(0.9976818)-Metabolism of carbohydrates(R)(0.9975402)-Metabolism of vitamins and cofactors(R)(0.9953394)-Plasma membrane estrogen receptor signaling(N)(0.9971338)-Proteogylcan syndecan-mediated signaling events(N)(0.9958148) 446 MYH8 17p13.1 0 0 0 0 7 1 513 0.5934 0 0.0583333333333333 Muscle contraction(R)(0.997359)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9979082)-Tight junction(K)(0.9963586)-Viral myocarditis(K)(0.998726)-Wnt signaling pathway(P)(0.998225) 447 CMA1 14q12 0 0 0 0 17 1 17 0.5934 0 0.141666666666667 Renin-angiotensin system(K)(0.9933784) 448 ACPP 3q22.1 0 0 0 0 2 1 16 0.5934 0 0.0166666666666667 () 449 HSD17B10 23p11.22 0 0 0 1 76 1 1259 0.5934 0 0.641666666666667 Alzheimer's disease(K)(0.9986868)-Metabolic pathways(K)(0.9988624)-Metabolism of amino acids(R)(0.9994646) 450 ACTL6A 3q26.33 0 2 1 0 0 1 150 0.5934 0 0.025 TNF alpha/NF-kB(C)(0.9981056)-control of gene expression by vitamin d receptor(B)(0.9767584) 451 HDAC1 1p35.1 0 0 0 0 4 1 1704 0.5934 0 0.0333333333333333 Cell cycle(K)(0.9848924)-Huntington's disease(K)(0.9993402)-IFN-gamma pathway(N)(0.9676374)-Pathways in cancer(K)(0.9968356)-Retinoic acid receptors-mediated signaling(N)(0.944181)-Signaling events mediated by the Hedgehog family(N)(0.9958462)-TGFBR(C)(0.9957722)-TNF alpha/NF-kB(C)(0.9967648)-Wnt signaling pathway(P)(0.9991824) 452 FZD1 7q21.13 0 0 6 0 1 1 1087 0.5934 0 0.0583333333333333 Angiogenesis(P)(0.996914)-Glypican pathway(N)(0.8694826)-Pathways in cancer(K)(0.9988396)-Wnt signaling pathway(K)(0.9659448)-Wnt signaling pathway(P)(0.9966828) 453 WARS2 1p12 0 0 0 0 5 1 82 0.5934 0 0.0416666666666667 Aminoacyl-tRNA biosynthesis(K)(0.997552)-Tryptophan metabolism(K)(0.9928592) 454 GUCA1A 6p21.1 0 1 0 0 5 1 418 0.5934 0 0.05 Phototransduction(K)(0.991527)-Visual signal transduction: Cones(N)(0.9863634) 455 AP1S3 2q36.1 0 0 0 0 1 1 264 0.5934 0 0.00833333333333333 Host Interactions of HIV factors(R)(0.9989196)-Lysosome(K)(0.9921436) 456 PANK1 10q23.31 0 0 0 2 82 1 1122 0.5934 0 0.7 Metabolic pathways(K)(0.999504) 457 ITGB7 12q13.13 0 0 0 0 5 1 814 0.5934 0 0.0416666666666667 Focal adhesion(K)(0.8705614)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9988852)-Integrin cell surface interactions(R)(0.9192644)-Regulation of actin cytoskeleton(K)(0.997974) 458 GAD2 10p12.1 0 0 2 1 74 1 1172 0.5934 0 0.641666666666667 Alanine, aspartate and glutamate metabolism(K)(0.996093)-Butanoate metabolism(K)(0.9978358)-Metabolic pathways(K)(0.9984906)-Type I diabetes mellitus(K)(0.997432) 459 CNGB1 16q13 0 0 0 0 4 1 421 0.5934 0 0.0333333333333333 () 460 UGT2B4 4q13.2 0 0 1 0 2 1 1198 0.5934 0 0.025 Metabolic pathways(K)(0.9961216)-Porphyrin and chlorophyll metabolism(K)(0.9889702) 461 DYRK1A 21q22.13 0 0 0 0 6 1 18 0.5934 0 0.05 Hedgehog(C)(0.992131) 462 TPM2 9p13.3 0 0 1 0 21 1 162 0.5934 0 0.183333333333333 Cardiac muscle contraction(K)(0.9977436)-Dilated cardiomyopathy(K)(0.9988698)-Muscle contraction(R)(0.9971774) 463 RFXANK 19p13.11 0 0 0 0 8 1 338 0.5934 0 0.0666666666666667 Antigen processing and presentation(K)(0.99796)-EGFR1(C)(0.9987114)-Primary immunodeficiency(K)(0.9979936)-Signaling events mediated by HDAC Class I(N)(0.9987838) 464 REN 1q32.1 0 4 1 0 0 1 17 0.5934 0 0.0416666666666667 () 465 CHST12 7p22.2 0 0 2 0 7 1 32 0.5934 0 0.075 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.998947) 466 SYT1 12q21.2 0 0 0 0 5 1 58 0.5934 0 0.0416666666666667 Botulinum neurotoxicity(R)(0.9710188) 467 EDEM1 3p26.2 0 0 1 0 1 1 172 0.5934 0 0.0166666666666667 Protein processing in endoplasmic reticulum(K)(0.9977204) 468 NOLC1 10q24.32 0 0 0 1 82 1 33 0.5934 0 0.691666666666667 integrin signaling pathway(B)(0.9987098) 469 A1CF 10q11.23 0 0 0 0 76 1 32 0.5934 0 0.633333333333333 mRNA Processing(R)(0.9980252) 470 MAFK 7p22.3 0 0 3 0 6 1 18 0.5934 0 0.075 oxidative stress induced gene expression via nrf2(B)(0.999261) 471 RALA 7p14.1 0 1 5 0 1 1 1071 0.5934 0 0.0583333333333333 FoxO family signaling(N)(0.9915416)-Glypican pathway(N)(0.9370284)-IFN-gamma pathway(N)(0.915522)-Pathways in cancer(K)(0.9984516)-Proteogylcan syndecan-mediated signaling events(N)(0.8647032)-Signalling by NGF(R)(0.997767)-TNF receptor signaling pathway(N)(0.9189824) 472 GARS 7p15.1 0 0 5 0 1 1 44 0.5934 0 0.05 Aminoacyl-tRNA biosynthesis(K)(0.9895254) 473 HSD17B12 11p11.2 0 0 0 0 9 1 1147 0.5934 0 0.075 Biosynthesis of unsaturated fatty acids(K)(0.9815564)-Metabolic pathways(K)(0.998374)-Steroid hormone biosynthesis(K)(0.8361382) 474 FOXA3 19q13.32 0 0 0 1 12 1 99 0.5934 0 0.108333333333333 FOXA transcription factor networks(N)(0.992327)-Regulation of beta-cell development(R)(0.996013) 475 SIP1 14q21.1 0 0 0 0 18 1 49 0.5934 0 0.15 Metabolism of non-coding RNA(R)(0.9995234) 476 SERPINB2 18q21.33 0 0 0 0 7 1 121 0.5934 0 0.0583333333333333 Amoebiasis(K)(0.9977234) 477 LDHD 16q23.1 0 0 0 0 7 1 40 0.5934 0 0.0583333333333333 () 478 ACSS1 20p11.21 0 0 0 0 3 1 1225 0.5934 0 0.025 Metabolic pathways(K)(0.9984012) 479 PRIM1 12q13.3 0 0 1 0 6 1 1321 0.5934 0 0.0583333333333333 G1/S Transition(R)(0.9373074)-Metabolic pathways(K)(0.9992592)-Purine metabolism(K)(0.997946)-Telomere Maintenance(R)(0.997255) 480 FUT9 6q16.1 0 0 0 0 9 1 1124 0.5934 0 0.075 Metabolic pathways(K)(0.9985434) 481 ACPT 19q13.33 0 0 0 0 11 1 16 0.5934 0 0.0916666666666667 Riboflavin metabolism(K)(0.9976368) 482 ARHGAP6 23p22.2 0 0 1 7 72 1 202 0.5934 0 0.666666666666667 Signaling by Rho GTPases(R)(0.9982642)-adp-ribosylation factor(B)(0.9969382)-rac1 cell motility signaling pathway(B)(0.9985898)-rho cell motility signaling pathway(B)(0.9968872)-t cell receptor signaling pathway(B)(0.9972352) 483 SMARCC2 12q13.2 0 0 1 0 7 1 332 0.5934 0 0.0666666666666667 Wnt signaling pathway(P)(0.9986322)-control of gene expression by vitamin d receptor(B)(0.8964928)-the information processing pathway at the ifn beta enhancer(B)(0.998694) 484 PLCB1 20p12.3 0 0 2 0 3 1 2605 0.5934 0 0.0416666666666667 Alzheimer's disease(K)(0.9841284)-Chagas disease(K)(0.9958642)-Formation of Platelet plug(R)(0.9875884)-Huntington's disease(K)(0.9982064)-Metabolic pathways(K)(0.9969754)-Wnt signaling pathway(P)(0.9972958) 485 NUP62 19q13.33 0 0 0 1 12 1 520 0.5934 0 0.108333333333333 HIV Life Cycle(R)(0.9976876)-Host Interactions of HIV factors(R)(0.998079)-Influenza Life Cycle(R)(0.998507)-Metabolism of carbohydrates(R)(0.996819)-Metabolism of non-coding RNA(R)(0.9939348)-Signaling events mediated by HDAC Class I(N)(0.9973338)-Transport of Mature Transcript to Cytoplasm(R)(0.9843148) 486 TERT 5p15.33 1 0 3 0 6 1 296 0.5934 0 0.0833333333333333 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9956014)-IL2-mediated signaling events(N)(0.9976902)-Regulation of Telomerase(N)(0.9994262)-Telomere Maintenance(R)(0.9992514)-erk1/erk2 mapk signaling pathway(B)(0.9334424)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.973576) 487 GCH1 14q22.3 0 0 0 0 18 1 1121 0.5934 0 0.15 Metabolic pathways(K)(0.9980582) 488 CRLS1 20p12.3 0 0 0 0 3 1 1136 0.5934 0 0.025 Metabolic pathways(K)(0.9991984) 489 PSPH 7p11.2 0 8 4 0 1 1 1125 0.5934 0 0.108333333333333 Metabolic pathways(K)(0.9986684) 490 NSDHL 23q28 0 0 0 0 77 1 1123 0.5934 0 0.641666666666667 Metabolic pathways(K)(0.9983668) 491 CYP27B1 12q14.1 3 16 0 1 3 1 1154 0.5934 0 0.191666666666667 Biological oxidations(R)(0.9976442)-Metabolic pathways(K)(0.998796)-Steroid biosynthesis(K)(0.850767) 492 BAK1 6p21.31 0 0 0 0 10 1 329 0.5934 0 0.0833333333333333 Apoptosis signaling pathway(P)(0.9964094)-Apoptosis(R)(0.9983098)-Protein processing in endoplasmic reticulum(K)(0.9982496) 493 B3GNT1 2p15 0 0 0 0 1 1 1127 0.5934 0 0.00833333333333333 () 494 RAD51L3 17q12 0 0 0 0 8 1 28 0.5934 0 0.0666666666666667 Homologous recombination(K)(0.997783) 495 HNRNPA1L2 13q14.3 0 0 0 0 38 1 128 0.5934 0 0.316666666666667 Spliceosome(K)(0.9985484) 496 NRXN1 2p16.3 0 0 0 1 2 1 135 0.5934 0 0.025 Cell adhesion molecules (CAMs)(K)(0.9932826) 497 CYB5R3 22q13.2 0 0 0 0 21 1 57 0.5934 0 0.175 Amino sugar and nucleotide sugar metabolism(K)(0.9989842)-Metabolism of vitamins and cofactors(R)(0.9973482) 498 MVD 16q24.3 0 0 0 0 27 1 1187 0.5934 0 0.225 Metabolic pathways(K)(0.9977906)-Metabolism of lipids and lipoproteins(R)(0.9992194)-Terpenoid backbone biosynthesis(K)(0.860568) 499 NCK1 3q22.3 0 0 0 0 1 1 916 0.5934 0 0.00833333333333333 downregulated of mta-3 in er-negative breast tumors(B)(0.997787) 500 PSMA5 1p13.3 0 0 0 0 5 1 437 0.5934 0 0.0416666666666667 Apoptosis(R)(0.9989584)-Host Interactions of HIV factors(R)(0.9977728)-Metabolism of amino acids(R)(0.9985774)-Signaling by Wnt(R)(0.9972544) 501 IGFALS 16p13.3 0 0 0 0 17 1 17 0.5934 0 0.141666666666667 Regulation of IGF Activity by IGFBP(R)(0.855374) 502 SH3KBP1 23p22.12 0 0 0 3 76 1 542 0.5934 0 0.658333333333333 EGFR1(C)(0.9980936)-Endocytosis(K)(0.9987608)-KitReceptor(C)(0.998138)-Proteogylcan syndecan-mediated signaling events(N)(0.997187)-Signaling by EGFR(R)(0.9974126) 503 CH25H 10q23.31 0 0 0 1 84 1 16 0.5934 0 0.708333333333333 Primary bile acid biosynthesis(K)(0.9994966) 504 RAG2 11p12 0 1 0 0 6 1 35 0.5934 0 0.0583333333333333 Primary immunodeficiency(K)(0.9741128) 505 CA6 1p36.23 0 0 0 1 16 1 23 0.5934 0 0.141666666666667 Nitrogen metabolism(K)(0.9968516) 506 FRK 6q22.1 0 0 0 0 15 1 62 0.5934 0 0.125 Parkinson disease(P)(0.9995378) 507 LRP6 12p13.2 0 0 0 1 11 1 866 0.5934 0 0.1 Alzheimer disease-presenilin pathway(P)(0.9972246)-Glypican pathway(N)(0.9973372)-Wnt signaling pathway(K)(0.9983312)-Wnt signaling pathway(P)(0.9990656)-Wnt(C)(0.996567)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9927658) 508 ATP6V1E1 22q11.21 1 0 0 0 16 1 1330 0.5934 0 0.133333333333333 Collecting duct acid secretion(K)(0.8398852)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9966514)-Metabolic pathways(K)(0.9985384)-Oxidative phosphorylation(K)(0.9955518)-Phagosome(K)(0.998689)-Vibrio cholerae infection(K)(0.9975984) 509 PTPRE 10q26.2 0 0 0 1 76 1 47 0.5934 0 0.641666666666667 IL6-mediated signaling events(N)(0.9989086) 510 NT5C3 7p14.3 0 0 6 0 1 1 1187 0.5934 0 0.0583333333333333 Metabolic pathways(K)(0.9986474)-Purine metabolism(K)(0.9966864) 511 FGF8 10q24.32 0 0 0 0 86 1 684 0.5934 0 0.716666666666667 FGF signaling pathway(P)(0.9982384)-MAPK signaling pathway(K)(0.9985944)-Pathways in cancer(K)(0.9987586)-Regulation of actin cytoskeleton(K)(0.999037)-Signaling by FGFR(R)(0.9742348) 512 ITGB3 17q21.32 3 0 0 0 2 1 1344 0.5934 0 0.0416666666666667 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9874244)-Cell surface interactions at the vascular wall(R)(0.9982336)-Formation of Platelet plug(R)(0.8353492)-Hematopoietic cell lineage(K)(0.996379)-Hypertrophic cardiomyopathy (HCM)(K)(0.9198408)-Integrin cell surface interactions(R)(0.9843282)-Integrin signalling pathway(P)(0.9975252)-Integrins in angiogenesis(N)(0.9708178)-Phagosome(K)(0.9981272)-Plasma membrane estrogen receptor signaling(N)(0.9048242)-Proteogylcan syndecan-mediated signaling events(N)(0.9944718)-Regulation of actin cytoskeleton(K)(0.9977624) 513 C9orf95 9q21.13 0 0 0 0 4 1 24 0.5934 0 0.0333333333333333 Nicotinate and nicotinamide metabolism(K)(0.9536974) 514 MYO1A 12q13.3 0 0 1 0 7 1 46 0.5934 0 0.0666666666666667 Nicotinic acetylcholine receptor signaling pathway(P)(0.9980882) 515 GP1BB 22q11.21 0 0 0 0 18 1 273 0.5934 0 0.15 ECM-receptor interaction(K)(0.9967698)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9832166)-Formation of Platelet plug(R)(0.9981562)-Hematopoietic cell lineage(K)(0.9976452) 516 ATG3 3q13.2 0 0 0 0 3 1 35 0.5934 0 0.025 () 517 CER1 9p22.3 0 0 1 0 38 1 352 0.5934 0 0.325 BMP receptor signaling(N)(0.9985324)-Signaling by BMP(R)(0.9970542)-Wnt signaling pathway(K)(0.9987756) 518 CENPF 1q41 1 0 0 0 3 1 129 0.5934 0 0.0333333333333333 () 519 BCMO1 16q23.2 0 0 0 0 7 1 1130 0.5934 0 0.0583333333333333 Metabolic pathways(K)(0.999069) 520 TAF1L 9p21.1 0 0 0 0 22 1 36 0.5934 0 0.183333333333333 Basal transcription factors(K)(0.9985992) 521 NCAM1 11q23.1 0 0 0 0 6 1 417 0.5934 0 0.05 Cell adhesion molecules (CAMs)(K)(0.999141)-Prion diseases(K)(0.9971724)-Proteogylcan syndecan-mediated signaling events(N)(0.9958594) 522 WHSC1L1 8p12 0 0 0 0 5 1 44 0.5934 1 0.0416666666666667 Lysine degradation(K)(0.9983018) 523 SMUG1 12q13.13 0 0 1 0 6 1 99 0.5934 0 0.0583333333333333 Base excision repair(K)(0.99722)-DNA Repair(R)(0.9987426) 524 YKT6 7p13 0 0 2 0 1 1 36 0.5934 0 0.025 () 525 KIT 4q12 1 9 5 0 1 1 870 0.5934 1 0.133333333333333 Acute myeloid leukemia(K)(0.8635968)-Cytokine-cytokine receptor interaction(K)(0.9981176)-Endocytosis(K)(0.9979646)-Hematopoietic cell lineage(K)(0.9982508)-KitReceptor(C)(0.9891424)-Melanogenesis(K)(0.997593)-Pathways in cancer(K)(0.9980996)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9962634) 526 ERBB2 17q12 7 0 0 3 13 1 739 0.5934 1 0.183333333333333 Adherens junction(K)(0.997334)-Alpha6Beta4Integrin(C)(0.9979982)-Calcium signaling pathway(K)(0.9983356)-EGF receptor signaling pathway(P)(0.995612)-Focal adhesion(K)(0.9983262)-Non-small cell lung cancer(K)(0.9353514)-Pathways in cancer(K)(0.9974626)-Prostate cancer(K)(0.9977874)-a6b1 and a6b4 Integrin signaling(N)(0.9945964) 527 BMP15 23p11.22 0 0 0 1 75 1 91 0.5934 0 0.633333333333333 TGF-beta signaling pathway(P)(0.9984012) 528 DUSP6 12q21.33 0 0 0 0 6 1 402 0.5934 0 0.05 MAPK signaling pathway(K)(0.9981698)-Signalling by NGF(R)(0.9982718) 529 LRP1 12q13.3 0 0 1 0 6 1 571 0.5934 0 0.0583333333333333 Alzheimer disease-presenilin pathway(P)(0.994529)-Alzheimer's disease(K)(0.9986874)-Malaria(K)(0.9965704)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9282654)-Wnt(C)(0.9981718)-amb2 Integrin signaling(N)(0.9971316) 530 OCRL 23q25 0 0 0 3 74 1 1271 0.5934 0 0.641666666666667 Inositol phosphate metabolism(K)(0.9973684)-Metabolic pathways(K)(0.9988404)-Phosphatidylinositol signaling system(K)(0.9984426)-Signaling by Rho GTPases(R)(0.998383) 531 ALG5 13q13.3 0 0 0 0 26 1 1123 0.5934 0 0.216666666666667 Metabolic pathways(K)(0.9971712)-N-Glycan biosynthesis(K)(0.8002374) 532 NDUFB6 9p21.1 0 0 0 0 24 1 1332 0.5934 0 0.2 Alzheimer's disease(K)(0.9990776)-Glucose Regulation of Insulin Secretion(R)(0.9979616)-Huntington's disease(K)(0.9974782)-Metabolic pathways(K)(0.9982218)-Parkinson's disease(K)(0.9941052) 533 OR6C1 12q13.2 0 0 1 0 11 1 389 0.5934 0 0.1 () 534 GAB3 23q28 0 0 0 2 76 1 82 0.5934 0 0.65 EGF receptor signaling pathway(P)(0.9987826) 535 CD200 3q13.2 0 0 0 0 3 1 111 0.5934 0 0.025 () 536 MGMT 10q26.3 0 0 0 0 77 1 85 0.5934 0 0.641666666666667 DNA Repair(R)(0.9993164) 537 MICA 6p21.33 0 0 0 0 5 1 219 0.5934 0 0.0416666666666667 Natural killer cell mediated cytotoxicity(K)(0.9977078) 538 CAPN6 23q22.3 0 0 0 4 75 1 134 0.5934 0 0.658333333333333 Huntington disease(P)(0.9988394) 539 PLAA 9p21.2 0 0 0 6 32 1 167 0.5934 0 0.316666666666667 Protein processing in endoplasmic reticulum(K)(0.9978896)