Airway Microbiome Dynamics in Exacerbations of Chronic Obstructive Pulmonary Disease

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Supplemental materials and methods; Tables S1 (Bacterial taxa that demonstrated the largest changes in relative abundance at the Post1 time point compared to the level at exacerbation), S2 (Bacterial taxa that demonstrated the largest changes in relative abundance at the Post1 time point compared to the level at exacerbation for the group treated with oral corticosteroids alone for exacerbation), S3 (Primers used for qPCR and taxon-specific sequencing experiments), and S4 (Concordance between microarray- and sequencing-based 16S rRNA datasets in reported relative abundances of indicated phyla and families); and Fig. S1 (Average weighted Unifrac distances representing within- and between-group differences in bacterial community composition) and S2 (Total 16S rRNA gene copy numbers shown by clinical time point and type of exacerbation treatment)

  PDF, 583K

• Supplemental file 2 -

  Table S5 (G2 PhyloChip dataset used for primary analyses)

  XLSX, 2.3M