Supplemental Data
Files in this Data Supplement:
- Movie Captions (.docx, 78 KB) - Captions for supplemental movies
- Movie 1 (.mov, 2.6 MB) - Movie 1: i27_no_force Zero-force simulation of I27 from the PDB structure 1TIT (100 ns simulation time)
- Movie 2 (.mov, 3.9 MB) - Movie 2: i27_stretch Stretching I27 from a near-native starting structure at 108 nm/s (120 ns simulation time)
- Movie 3 (.mov, 1.6 MB) - Movie 3: SAH_no_force Zero-force simulation of M10 SAH from a long helix starting structure (100 ns simulation time)
- Movie 4 (.mov, 1.3 MB) - Movie 4: myo10_SAH Stretching M10 from a long helix starting structure at 108 nm/s (~100 ns simulation time)
- Movie 5 (.mov, 2.9 MB) - Movie 5: a97_no_force Zero-force simulation of A97 from a long helix starting structure (100 ns simulation time)
- Movie 6 (.mov, 1.3 MB) - Movie 6: a97_stretch Stretching A97 from a long helix starting structure at 108 nm/s (~90 ns simulation time)
- Movie 7 (.mov, 3.3 MB) - Movie 7: g97_no_force Zero-force simulation of G97 from a long helix starting structure (100 ns simulation time)
- Movie 8 (.mov, 2.1 MB) - Movie 8: g97_stretch Stretching G97 from a collapsed coil starting structure at 108 nm/s (100 ns simulation time)
- Movie 9 (.mov, 2.4 MB) - Movie 9: myo10_stretch_relax Stretching M10 from a long helix starting structure at 108 nm/s and then reversing the direction of pull (–108 nm/s) allowing the protein to refold (~200 ns simulation time)
- Movie 10 (.mov, 2.8 MB) - Movie 10: myo10_full_stretch_relax Stretching M10 from a long helix starting structure at 1010 nm/s to a fully extended non-helical chain structure and then reversing the direction of pull (–108 nm/s) allowing the protein to refold (~200 ns simulation time).