Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Fig. S1 and S2, Tables S1 and S2, and legends for Movies S1 to S7.

  PDF, 141K

• Supplemental file 2 -

  Time-lapse microscopy of invasive hyphal growth in the hindbrain ventricle of highly immunosuppressed pu.1 morphant larvae (Movie S1).

  MOV, 2.3M

• Supplemental file 3 -

  Time-lapse microscopy of macrophages rapidly phagocytosing A. fumigatus conidia (Movie S2).

  MOV, 6.1M

• Supplemental file 4 -

  Time-lapse microscopy of macrophage inflammation around A. fumigatus hyphae (Movie S3).

  MOV, 3.2M

• Supplemental file 5 -

  Time-lapse microscopy of neutrophils and A. fumigatus conidia (Movie S4).

  MOV, 2.6M

• Supplemental file 6 -

  Time-lapse microscopy of neutrophils in macrophage-deficient irf8 morphant larvae with A. fumigatus conidia (Movie S5).

  MOV, 3.1M

• Supplemental file 7 -

  Time-lapse microscopy of neutrophils colocalizing with, migrating towards, and adhering to A. fumigatus hyphae (Movie S6).

  MOV, 7.5M

• Supplemental file 8 -

  Time-lapse microscopy of neutrophils in macrophage-deficient irf8 morphant larvae with A. fumigatus ΔlaeA conidia (Movie S7).

  MOV, 1.9M