LcrV Delivered via Type III Secretion System of Live Attenuated Yersinia pseudotuberculosis Enhances Immunogenicity against Pneumonic Plague

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Supplemental methods. Legends for Fig. S1 through S4.

  PDF, 165K

• Supplemental file 2 -

  Fig. S1. Mass spectrometry analysis of lipid A from Y. pseudotuberculosis PB1+, χ10052, and χ10055 grown at 26°C or 37°C.

  PDF, 379K

• Supplemental file 3 -

  Fig. S2. Proposed chemical structures of Y. pseudotuberculosis lipid A species at 26°C based on MALDI-MS data.

  PDF, 503K

• Supplemental file 4 -

  Fig. S3. Proposed chemical structures of Y. pseudotuberculosis lipid A species at 37°C based on MALDI-MS data.

  PDF, 240K

• Supplemental file 5 -

  Fig. S4. Antigen-specific IL-4 cytokine in the culture supernatants produced from splenic cells and the ratio of IFN-γ with IL-4.

  PDF, 31K