Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex

Supplemental Materials

This article contains the following supporting material:

  • Supplemental Materials
  • Movie01 - Supplemental Movie 1 Axin-GFP puncta are stable and rarely split or merge with neighboring puncta.
  • Movie02 - Supplemental Movie 2 Similar to Axin-GFP alone, Axin-GFP/APC2-FL puncta are also stable and rarely split or merge with neighboring puncta.
  • Movie03 - Supplemental Movie 3 Axin-GFP/APC2-ΔASAD puncta are highly dynamic and frequently split and merge with neighboring puncta.