Orobanche spp. are major parasitic weeds of vegetable crops. Two mycoherbicidal Fusarium species are examined by Cohen et al. (pp. 567-578) for their potential in biological control. The aetiology of pathogenesis and the biological responses of Orobanche infected by Fusarium are examined, and the kinetics of infection biochemically and histochemically tracked using light, confocal and electron microscopy.