Use of Immunodampening To Overcome Diversity in the Malarial Vaccine Candidate Apical Membrane Antigen 1

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    Fig. S1. AMA1 ala and ser mutants do not bind MAb 1F9, but reactivity with other conformationally sensitive antibodies is retained. Fig. S2. Immune response to the wt antigen of rabbits immunized with wt or mutant AMA1. Fig. S3. Loop Id mutants induce a mutant-specific antibody response. Fig. S4. Effect of purified IgG from rabbits immunized with combined antigens on the growth of various parasite lines. Table S1. IgG concentrations and percent parasite inhibition used to calculate relative growth inhibition of heterologous versus homologous parasite lines. Table S2. IgG concentrations and percent parasite inhibition used to calculate relative growth inhibition of heterologous versus homologous parasite lines.

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