Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis

Supplemental Materials

This article contains the following supporting material:

  • Supplemental Materials
  • Movie03 - Figure 2 video S3. Time-lapse movie of HeLa cells transfected with control and MgcRacGAP siRNA undergoing failed cytokinesis.
  • Movie04 - Figure 2 video S4. Time-lapse movie of HeLa cells transfected with Trio#2 and MgcRacGAP siRNA undergoing cytokinesis. Trio depletion rescued the cytokinesis failure induced by MgcRacGAP depletion.
  • Movie02 - Figure 2 video S2. Time-lapse movie of HeLa cells transfected with Trio#2 siRNA undergoing cytokinesis.
  • Movie01 - Figure 2 videoS1. Time-lapse movie of HeLa cells transfected with control siRNA undergoing cytokinesis.