Table S2.Characteristics ofthestudypopulationby PPH (estimated blood loss >500ml)or noPPH,following correctionoferrors, categorisationand weighting. Demography No PPH PPH >500ml All No.of women/notesreviewed 653 1242 1895 No.of womenrepresented(nw) 6585 3352 9937 Age (years) % of population <20 5.0 2.8 4.2 20-24 15.9 8.9 13.5 25-29 22.4 22.0 22.2 30-34 32.0 36.6 33.6 35-39 19.8 22.6 20.7 40+ 5.0 7.2 5.7 Ethnicity White 61.2 55.3 59.2 BlackBritish 2.4 1.0 2.0 BlackCaribbean 4.4 4.2 4.3 BlackAfrican 14.2 22.3 16.9 Bangladeshi 2.0 1.1 1.7 Indian 3.0 3.8 3.3 Pakistani 3.7 3.9 3.7 OtherAsian 0.7 0.9 0.8 Chinese 0.6 1.3 0.8 Mixed 3.0 1.6 2.6 Unknown 4.8 4.5 4.7 Body MassIndex(BMI)(kg/m2) <19 6.3 4.8 5.8 19-24.9 50.8 51.2 50.9 25-29.9 22.3 22.3 22.3 30-34.9 10.3 11.9 10.8 35+ 4.1 4.8 4.4 Indexofmultiple deprivation Quintile 1(least deprived) 7.3 6.6 7.1 Quintile 2 9.8 10.1 9.9 Quintile 3 14.1 15.2 14.5 Quintile 4 29.5 28.0 29.0 Quniltile 5 (Most deprived) 38.8 39.3 39.0 Parity Primiparity 47.0 58.8 51.0 Smoking Atbooking 13.2 10.2 12.2 Previous obstetric history (includes primiparouswomen) No previous PPH 96.5 94.7 95.9 1 x previous PPH 3.5 4.8 3.9 >1previousPPH 0 0.3 0.1 PreviousCaesarean section 9.2 22.6 13.7 Pre-existing medicalconditions Diabetes 0.9 1.2 1.0 Epilepsy (onmedication) 0.4 0.7 0.5 Depression(onmedication) 2.8 2.2 2.6 Hypertension 0.7 1.6 1.0 Fibroids 3.8 6.1 4.5 Female genitalmutilation 2.8 3.3 2.9 Clotting orthromboembolic disorder 0.6 1.8 1.0 Uterine abnormality 0.2 0.3 0.2 Assistedconception 1.3 4.8 2.5 Currentpregnancy Multiple pregnancy 1.8 4.0 2.6 Antenataladmissions 14.3 19.1 15.9 Anyantenatalday unit attendance 47.3 53.6 49.5 Abdominalpain 15.7 17.2 16.3 Itching 2.0 2.3 2.1 Externalcephalic version 1.3 1.8 1.5 Pre-eclampsiascreen 6.8 10.7 8.1 Reduced fetalmovements 12.8 14.4 13.3 Possible spontaneous ROM 13.8 15.3 14.3 Generally unwell(nodiagnosis) 3.1 3.8 3.3 Possible UTI 0.0 0.4 0.1 Vaginalbleed (noadmission) 3.9 3.8 3.8 Placentapraevia 0.2 1.4 0.6 APHrequiring admission 3.4 4.6 3.8 UTI (confirmed) 9.0 9.9 9.3 Gestationalhypertension 2.1 4.6 2.9 Pre-eclampsia 0.9 4.3 2.1 Anaemia(Hb<10.5g/ml) 12.4 14.1 12.9 Intrapartum Spontaneousonset of labour 74.7 51.3 66.8 Inducedonset of labour 14.2 19.3 15.9 Augmentedonset of labour 5.0 6.9 5.6 No labourelectiveCaesarean# 6.2 22.5 11.7 Temperature(>37.2°C) 12.3 27.8 17.3 Rupturedmembranes>48h 2.7 4.1 3.2 Prostin 13.1 18.0 14.8 Syntocinontoinduce or augmentlabour 18.4 35.9 24.3 Birth SVD 76.1 25.9 59.2 Instrumentalvaginaldelivery* 12.1 17.1 13.8 Elective Caesareansection# 5.6 18.4 9.9 Emergency Caesarean section 6.2 38.6 17.1 Third stageof labour Physiological 9.2 3.4 7.2 SyntocinonIM 7.3 5.4 6.7 SyntocinonIV 13.4 58.1 28.5 Syntometrine IM 69.7 30.8 56.6 Retainedplacenta 1.3 4.4 2.4 nw;Numberof womenrepresentedby the reviewednotes allowingforthe weighted sampling. *Forcepsorventouse; #Figuresdifferas some womenplanningelective Caesarean sectionhad onset of labour,so Caesareansectionclassified asemergency.