A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo

Data Supplement

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  • Supplemental Data -

    Supplemental Figure 1 - A) Inhibition of native mKCa3.1-whole-cell-currents by RA-2 in murine fibroblast...

    Supplemental Figure 2 - Representative whole-cell recordings showing that RA-2 did not inhibit hKCa1.1 in U251 glioblastoma cells...

    Supplemental Figure 3 - A) Mean arterial blood pressure (MAP) and heart rate (HR) after intraperitoneal injections...

    Supplemental Table 1 - Effects of RA-2 on other K+ channels