index,SNP,gene,beta,t.stat,p.value,FDR,R2,CHR,A1,A2,MAF,NCHROBS,chrmProbe,s1,s2,chrm_snp,pos,Disease / Trait 14,rs1063355,7160474_HLA-DQB1,-1.475645807,-18.09079537,6.75E-34,9.66E-29,0.754776352,6,A,C,0.4339,242,chr6,32736001,32736004,chr6,32735692,"[Allergic sensitization],[Asthma],[Celiac disease],[Chronic hepatitis B infection],[Coronary heart disease],[Crohn's disease],[Drug-induced liver injury (amoxicillin-clavulanate)],[Epstein-Barr virus immune response (EBNA-1)],[Follicular lymphoma],[Graves' disease],[HPV seropositivity],[Height],[Hepatitis B],[Hepatocellular carcinoma (hepatitis B virus related)],[Hypothyroidism],[IgA nephropathy],[IgE grass sensitization],[IgE levels ],[Knee osteoarthritis],[Lymphoma],[Multiple sclerosis],[Multiple sclerosis (OCB status)],[Nephropathy],[Nodular sclerosis Hodgkin lymphoma],[Primary biliary cirrhosis],[Prostate cancer],[Pulmonary function],[Pulmonary function (interaction)],[Rheumatoid arthritis],[Self-reported allergy],[Systemic lupus erythematosus],[Systemic sclerosis],[Type 1 diabetes],[Ulcerative colitis]" 32,rs9276,1050360_HLA-DPB1,0.725287269,14.06919855,8.16E-26,3.30E-21,0.634013589,6,A,G,0.1694,242,chr6,33054752,33054801,chr6,33161555,"[Aspirin exacerbated respiratory disease in asthmatics],[Asthma],[Chronic hepatitis B infection],[Hepatitis B],[Hepatitis B (viral clearance)],[Hepatitis B vaccine response],[Nephropathy],[Systemic sclerosis],[Wegener's granulomatosis]" 100,rs698207,3780554_CRBN,-0.441881241,-10.18913577,2.54E-17,2.67E-13,0.093981754,3,G,A,0.09244,238,chr3,3191953,3192002,chr3,3179733,"[Asthma (childhood onset)],[Bipolar disorder],[Callous-unemotional behaviour],[Disc degeneration (lumbar)],[IgG glycosylation],[Immune response to smallpox vaccine (IL-6)],[Pancreatic cancer],[Response to amphetamines],[White matter integrity]" 242,rs7192,2570564_HLA-DRA,0.182496272,7.357619122,4.51E-11,1.30E-07,0.212790185,6,A,C,0.3182,242,chr6,32412513,32412562,chr6,32519624,"[""Cholesterol, total""],[Anti-cyclic Citrullinated Peptide Antibody],[Asthma],[Complement C3 and C4 levels],[Crohn's disease],[Cystic fibrosis severity],[Hematological parameters],[Hepatitis B vaccine response],[Hepatitis C induced liver cirrhosis],[Hodgkin's lymphoma],[LDL cholesterol],[Lymphoma],[Multiple sclerosis],[Multiple sclerosis (OCB status)],[Non-obstructive azoospermia],[Parkinson's disease],[Prostate cancer],[Pubertal anthropometrics],[Rheumatoid arthritis],[Systemic sclerosis],[Type 1 diabetes],[Ulcerative colitis],[Vitiligo]" 254,rs9963424,510224_LPIN2,0.166445294,7.218272632,8.94E-11,2.40E-07,0.176808152,18,G,A,0.438,242,chr18,2919444,2919493,chr18,3049507,"[Body mass index (asthmatics)],[Type 2 diabetes]" 279,rs8067378,1500112_ORMDL3,-0.207973543,-6.998141119,2.61E-10,6.25E-07,0.236124984,17,G,A,0.4669,242,chr17,35331072,35331121,chr17,35304874,"[Asthma],[Crohn's disease],[Hematological parameters],[Inflammatory bowel disease],[Primary biliary cirrhosis],[Type 1 diabetes],[Type 1 diabetes autoantibodies],[Ulcerative colitis],[White blood cell count]" 302,rs2290400,6270615_GSDMB,-0.224568026,-6.797237208,6.89E-10,1.49E-06,0.199825353,17,G,A,0.4458,240,chr17,35314497,35314546,chr17,35319766,"[Asthma],[Cervical cancer],[Crohn's disease],[Inflammatory bowel disease],[Primary biliary cirrhosis],[Rheumatoid arthritis],[Self-reported allergy],[Type 1 diabetes],[Type 1 diabetes autoantibodies],[Ulcerative colitis],[White blood cell count]" 470,rs11950562,7050180_SLC22A5,-0.120172807,-5.563341062,2.07E-07,0.000230668,0.083590611,5,C,A,0.425,240,chr5,131758857,131758906,chr5,131680428,"[Asthma],[Crohn's disease],[Fibrinogen],[Height],[IgG glycosylation],[Inflammatory bowel disease]" 482,rs2290400,5390608_GSDMB,-0.189561212,-5.491406936,2.84E-07,0.000303896,0.146796586,17,G,A,0.4458,240,chr17,35315636,35315685,chr17,35319766,"[Asthma],[Cervical cancer],[Crohn's disease],[Inflammatory bowel disease],[Primary biliary cirrhosis],[Rheumatoid arthritis],[Self-reported allergy],[Type 1 diabetes],[Type 1 diabetes autoantibodies],[Ulcerative colitis],[White blood cell count]" 527,rs2710706,4590064_CDK2,0.125618445,5.282650355,7.04E-07,0.000667645,0.054904437,12,A,C,0.1583,240,chr12,54652439,54652488,chr12,53724359,"[Asthma],[Type 1 diabetes],[Vitiligo]" 601,rs17772583,1400253_RAD50,-0.161040302,-5.032419253,2.04E-06,0.00166411,0.145721007,5,G,A,0.1818,242,chr5,131954817,131954866,chr5,131981409,"[Asthma],[IgE levels ]" 624,rs2227315,6040598_GSDMB,0.157609085,4.951361704,2.86E-06,0.00221176,0.087023384,17,A,G,0.2815,238,chr17,35327227,35327276,chr17,35423240,"[Asthma],[Cervical cancer],[Crohn's disease],[Inflammatory bowel disease],[Primary biliary cirrhosis],[Rheumatoid arthritis],[Self-reported allergy],[Type 1 diabetes],[Type 1 diabetes autoantibodies],[Ulcerative colitis],[White blood cell count]" 685,rs73574266,3420402_KIAA1271,-0.200980469,-4.813667812,5.04E-06,0.003554081,0.139634749,20,A,G,0.1446,242,chr20,3796792,3796841,chr20,3820566,[Asthma] 832,rs7593743,620072_DNAJC27,0.122760411,4.485269897,1.88E-05,0.010411888,0.029722984,2,A,G,0.1157,242,chr2,25020199,25020248,chr2,25048090,"[Body mass index],[Body mass index (non-asthmatics)],[Height],[Obesity],[Pubertal anthropometrics],[Type 1 diabetes]" 861,rs17132413,4880386_SLC25A46,-0.191652431,-4.440624926,2.24E-05,0.011953478,0.01637682,5,G,A,0.07438,242,chr5,110126114,110126163,chr5,110195432,"[Allergic rhinitis],[Allergic sensitization],[Asthma],[Cardiac structure and function],[IgE grass sensitization]" 934,rs17878498,830519_IL5RA,-0.191904285,-4.334800695,3.38E-05,0.016483449,0.127664167,3,A,C,0.1736,242,chr3,3108948,3108997,chr3,3127930,"[Asthma (childhood onset)],[Immune response to smallpox vaccine (IL-6)],[Oleic acid (18:1n-9) plasma levels],[QT interval]" 1016,rs1861867,1710474_CHD9,0.103189091,4.243440664,4.79E-05,0.021623736,0.005337718,16,A,G,0.3458,240,chr16,51918192,51918241,chr16,52406062,"[Asthma (childhood onset)],[Bipolar disorder],[IgG glycosylation],[Tetralogy of Fallot],[Type 2 diabetes]" 1099,rs1475908,5490470_MX2,0.20091899,4.165797271,6.42E-05,0.027053071,0.177030124,21,A,G,0.1807,238,chr21,41702511,41702560,chr21,41853927,"[Airflow obstruction ],[Cardiac repolarization],[Conduct disorder (case status)],[Melanoma],[Metabolite levels (MHPG)],[Obesity-related traits],[Pulmonary function in asthmatics]" 1101,rs1015166,4200452_HLA-DOA,-0.199523822,-4.164393314,6.46E-05,0.02717019,0.195797256,6,A,G,0.2066,242,chr6,33080184,33080233,chr6,32906709,"[Asthma],[IgG glycosylation],[Platelet counts],[Wegener's granulomatosis]" 1168,rs7906772,4810753_EMX2OS,-0.162735984,-4.10246182,8.14E-05,0.032338757,0.059051798,10,A,G,0.06612,242,chr10,119244647,119244696,chr10,118912172,"[Bipolar disorder and schizophrenia],[Cardiac repolarization],[Pulmonary function in asthmatics]" 1206,rs13393590,3800050_ADCY3,-0.12128778,-4.079543276,8.86E-05,0.034486323,0.101372693,2,G,A,0.2851,242,chr2,24895600,24895649,chr2,25001180,"[Body mass index],[Body mass index (non-asthmatics)],[Height],[Inflammatory bowel disease],[Obesity],[Pubertal anthropometrics],[Type 1 diabetes]" 1208,rs13356883,1770114_PDE4D,0.225173294,4.078249825,8.90E-05,0.034604174,0.046634877,5,G,A,0.05372,242,chr5,58302551,58302600,chr5,58672295,"[Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)],[Asthma],[Breast cancer],[Esophageal cancer],[Immune response to smallpox vaccine (IL-6)],[Neuroticism],[Obesity-related traits],[Response to antipsychotic treatment],[Sleepiness]" 1261,rs62208400,4890292_TSHZ2,0.293589815,4.033636094,0.000104989,0.039049553,0.167753401,20,C,G,0.04959,242,chr20,51306317,51306366,chr20,51803134,"[Attention deficit hyperactivity disorder],[Body mass index (non-asthmatics)],[Hemoglobin]" 1357,rs396746,1340475_BRD2,0.119221306,3.967370896,0.000133801,0.046587307,0.070042107,6,A,C,0.1471,238,chr6,33056979,33057028,chr6,33665023,"[Asthma],[IgG glycosylation],[Response to treatment for acute lymphoblastic leukemia]" 1378,rs13192436,1190039_HLA-DPA1,0.134431044,3.953828633,0.000140555,0.0482715,0.13024761,6,A,G,0.2395,238,chr6,33144417,33144466,chr6,33707957,"[Aspirin exacerbated respiratory disease in asthmatics],[Asthma],[Chronic hepatitis B infection],[Hepatitis B],[Hepatitis B (viral clearance)],[Nephropathy],[Systemic sclerosis]" 1425,rs4382936,540440_FCHSD2,0.125479702,3.921464778,0.000158039,0.052568962,0.086033124,11,C,A,0.3833,240,chr11,72225502,72225551,chr11,72630048,"[Body mass index (asthmatics)],[Crohn's disease],[Insomnia (caffeine-induced)]" 1453,rs17083258,2470136_TLE4,-0.143984469,-3.90665326,0.000166716,0.054570391,0.059542923,9,C,A,0.1198,242,chr9,81530777,81530826,chr9,82200505,"[Asthma (childhood onset)],[Bipolar disorder],[Menopause (age at onset)]" 1509,rs8034421,6840328_SMAD3,-0.091134317,-3.879512867,0.000183808,0.058493708,0.049312934,15,A,G,0.3208,240,chr15,65274286,65274335,chr15,65289626,"[Asthma],[Corneal structure],[Coronary heart disease],[Crohn's disease],[Inflammatory bowel disease],[Self-reported allergy]" 1547,rs7259041,7000609_ARRDC2,-0.095480067,-3.860273933,0.000196924,0.061398055,0.107076345,19,G,A,0.2314,242,chr19,17985646,17985695,chr19,17984738,[Pulmonary function in asthmatics] 1587,rs6725214,3440138_CLK1,0.299192375,3.837250657,0.000213792,0.065097417,0.009352658,2,A,C,0.04132,242,chr2,201428008,201428054,chr2,202426827,"[Asthma (childhood onset)],[Breast size],[Heart rate variability traits],[Height],[Non-alcoholic fatty liver disease],[Obesity-related traits],[Vertical cup-disc ratio]" 1740,rs61995576,6840075_NP,0.148104419,3.745680267,0.000295511,0.081330911,0.092982954,14,G,A,0.06612,242,chr14,20014881,20014930,chr14,20079159,"[Asthma (toluene diisocyanate-induced)],[Central corneal thickness],[Corneal structure],[Creutzfeldt-Jakob disease],[Creutzfeldt-Jakob disease (variant)],[Menopause (age at onset)],[Phospholipid levels (plasma)],[Platelet aggregation],[Prion diseases],[Response to antipsychotic therapy (extrapyramidal side effects)]" 1785,rs7898983,4040097_KLF6,0.095969111,3.727243507,0.000315217,0.084916966,0.067229178,10,G,A,0.1901,242,chr10,3811452,3811501,chr10,4682213,"[Asthma (bronchodilator response)],[Attention deficit hyperactivity disorder and conduct disorder],[Body mass index],[Bone mineral density],[Capecitabine sensitivity],[Crohn's disease],[Economic and political preferences (environmentalism)],[Longevity],[Multiple myeloma (IgH translocation)],[Reading and spelling],[Sex hormone-binding globulin levels],[Word reading]" 1828,rs1806516,4150408_P2RY2,-0.153353289,-3.706555365,0.000338813,0.089039222,0.094823369,11,G,A,0.3292,240,chr11,72624553,72624602,chr11,72681701,"[Body mass index (asthmatics)],[Crohn's disease],[Insomnia (caffeine-induced)]" 1832,rs2901117,2340008_PDZD8,0.126028886,3.704054561,0.000341777,0.089560936,0.078704266,10,G,A,0.09091,242,chr10,119043947,119043996,chr10,118417769,"[Bipolar disorder and schizophrenia],[Cardiac repolarization],[Pulmonary function in asthmatics]" 1838,rs1704186,7380221_SPATS2L,-0.161158803,-3.701703127,0.000344586,0.090080867,0.041681157,2,A,C,0.1292,240,chr2,201051039,201051088,chr2,200477784,"[Asthma (bronchodilator response)],[Exercise (leisure time)],[Response to treatment for acute lymphoblastic leukemia]" 1879,rs830574,2450608_ACO1,0.144313266,3.683552523,0.000367016,0.093890596,0.078145213,9,A,G,0.09917,242,chr9,32440622,32440671,chr9,33218189,"[Asthma],[IgG glycosylation]" 1896,rs746049,630110_SUOX,-0.118035336,-3.677805584,0.000374402,0.095158395,0.102530134,12,A,G,0.2562,242,chr12,54685480,54685529,chr12,55635306,"[Alopecia areata],[Asthma],[Polycystic ovary syndrome],[Type 1 diabetes],[Type 1 diabetes autoantibodies],[Vitiligo]" 1913,rs2254514,4860762_INPP4B,-0.086811399,-3.669597223,0.000385196,0.097004915,0.061267027,4,A,G,0.2355,242,chr4,143222645,143222694,chr4,142859988,[Asthma] 1933,rs10467589,3120332_OR7E156P,-0.103077957,-3.661975299,0.000395482,0.098652246,0.131667717,13,G,A,0.157,242,chr13,63212370,63212377,chr13,64086444,"[Asthma],[Bone mineral density],[IgG glycosylation],[Pancreatic cancer],[QT interval]"