MAFFT SCT1 GPT2 >Saccharomycescerevisiae_YBL011W MPAP---------------------------------------KLTEKFAS--------- ---SKSTQKTTN--YSSIEAKSVKTSADQAYIYQEPSATKKILYSIATWLLYNIFHCFFR EIRGRGSFKVPQQG-PVIFVAAPHANQFVDPVILMGEVKK----------SVNRRVSFLI AESSLK-QPPIGFLASFFMAIGVVRPQDNLKPAEGTIRV---DPT-DYKRVIGHDT---- ---HFL-TDCMPKGLIGLPK-SMG----FGEIQSIESDTSLTLRKEFKMAKP-------- -------------EIKTALLTGTTYKYAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHD RTNLLPLKAGVAIMALGCMD--KHPDVN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIEIPKELVAKYH-NPETNRDAVKELLDTISKGLQSVTVTCSDYETLMVVQ TIRRLYMTQF---------------STKLPLPLIVEMNRRMVKGYEFYRNDPKIADLTKD IMAYNAALRHYNLPDHLVEEA----KVNFAKNLGLVFFRSIGLCILFSLAMPGIIMFSPV FILAKRISQEKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYYLRHKP ----------------WNK-IYVFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSL- -TSPKG----LQKLQKDRRNLAERIIEVVNNFGSELFP-DFDSAALREEF---------- -------------DVIDEEEEDRKTSE----------LNRRKMLRKQKIKRQEKDSSS-- ---------PIISQRDNHDAYEHHNQDSDGV--SLVNSDNSLSNIPLFSSTFHRKSESS- ----------------------LASTSVAP----------------------------SS S----S-------EFEVE-------NEIL---------EEK--NGLASKIA----QAVLN K--------RIGENTA------------REEEEEEEEEEEEEEEEEEGKEGDA >Saccharomycesparadoxus_Spar_2.124 MPAP---------------------------------------KLTEKSAS--------- ---SRSTQETTN--SNSIKAKGAKTSAEQAYVYREPSATKKILYSIATWLLYNIFHCFFR EIRGRGSFKVPQQG-PVIFVAAPHANQFVDPVILMGEVKK----------SVNRRVSFLI AENSLK-QPAIGFLASFFMAIGVVRPQDNLKPAKGTIRV---DPT-DYKRVIGHDT---- ---HFL-TDCMPKGLIGLPK-SMG----FGEIQSIESDTSLTLRKEFKMVKP-------- -------------EVKTALLNGTSYKYAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHD RTDLLPLKAGVAIMALGCMD--QHPDVN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIEIPKELVAKYH-NPETNREAVKELLDTISKGLQSVTVTCSDYETLMVVQ TIRRLYMTQF---------------STKLPLPLIVEMNRRMVKGYEFYRNDPKIADLTKD IMAYNAALRHYNLPDHLVEEA----KVNFAKNLGLVFFRSIGLCILFSLAMPGIIMFSPV FILAKRISQEKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYYLRHKP ----------------WNN-IYIFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSL- -TSPKG----LQKLQKDRRNLAERIIEVVNNFGSELFP-DFDSAALREEF---------- -------------DVIDEEEEDRKTSE----------LNRRKLLRKQKIRRQERDPLS-- ---------STINQHDNQETYEHHNQDSDGV--SLVNSDNSLSNIPLFSSTFHRKSESS- ----------------------LASTSVAP----------------------------SS S----S-------EFEID-------NEIL---------EEK--NGLASKIA----QAVLN K--------RIGENAA------------REEEENQQQQQE-------GEEGDA >Saccharomycesmikatae_Smik_2.109 MPAP---------------------------------------KLTEKLAS--------- ---SENAQETTNCSSSSTKVKDTKTSAEQAYVYKEPSATKKILYSIATWLLYNIFHCFFR EIRGRGSFKVPQQG-PLIFVAAPHANQFVDPVILMGEVKK----------SVNRRVSFLI AENSLK-QPAIGFLASFFMAIGVVRPQDNLKPAKGTIRV---DPT-DYKRVIGHDT---- ---HFL-TDCMPKGLIGLPK-SMG----FGEIQSIESDTSLTLRKEFKMVKP-------- -------------EIKTALLNGTSYKYASKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHD RTNLLPLKAGVAIMALGCMD--KHPDVN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIEIPKDLVAKYH-NPETNRDAVKELLDTISKGLQSVTVTCSDYETLMVVQ TIRRLYMTQF---------------SSKLPLPLIVEMNRRMVKGYEFYRNDPKIKDLTKD IMAYNAALRHYNLPDHLVEEA----KVNFAKNLGLVFFRLIGLCILFSLAMPGIIMFSPV FILAKRISQEKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYYLRYKP ----------------WNR-IYVFSGSYMSCVIVTYSALIVGDIGMDGFKSLRPLVLSL- -TSPKG----LQKLQKDRRNLAERIIEVVNNFGSELFP-DFDSAALREEF---------- -------------DVIDEEEEDRKTSE----------LNRRKMLRKQKVKRQEKNSSS-- ---------FIINEHDNHDTYEHHNQDSDGI--SLVNSDNSLSNIPLFSSTFHRKSESS- ----------------------LASASVAA----------------------------SS S----S-------EFEIE-------NDIL---------EEK--NGLANKIA----QAVMN K--------RIGENAA------------REEEEEEEEKQE------------- >Saccharomyceskudriavzevii_Skud_2.100 MPAP---------------------------------------KLTEKPVS--------- ---SKNAQEDTS--PTSTKANGAEAATEQVYVYKEPSAATKMMYSIATWLLYNIFHCFFR EIRGRGSFKVPQQG-PLIFVAAPHANQFVDPVILMGEVKK----------SVNRRVSFLI AENSLK-QPVIGFLASFFMAIGVVRPQDNLKPAKGTIRV---DPT-DYKRVIGRDT---- ---HFL-TDCLPKGLIGLPK-SMG----FGEIQSIESDTSLTLRKEFKMVKP-------- -------------EVKSALLNGTTYKFAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHD RTDLLPLKAGVAIMALGCME--KHPDVN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIEIPKELIAKYH-NPETNREAVKELLDTISKGLQSVTVTCSDYETLMVVQ TIRRLYMTQF---------------SSKLPLPLIVEMNRRMVKGYEFYRNDPKIVDLRKD IMAYNAALRHYNLPDHQVEEA----RVNFAKNLGLVFFRLIGLCILFSLAMPGIIMFSPV FILAKRISQKKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYYLRHQP ----------------WNK-IYIFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSL- -TSPKG----LQKLQKDRASLAERIIEVVNNFGSELFP-DFDSAALREEF---------- -------------DVIDEEEEDRKTSE----------LIRRKMLRKQKIRRQERDPSL-- ---------SATDGHVNHDVYEHHNQDSDGV--SLVNSDNSLSNIPLFSSTFHRKSESS- ----------------------LTSTSVAP----------------------------SS S----S-------EFELE-------DESL---------EEK--NGLASKIA----QAVMN R--------RIGENAA------------REEDERDEDT--------------- >Saccharomycesbayanus_Sbay_2.114 MPAP---------------------------------------KLTEKPVS--------- ---SKQVQETTS-ASASPSTAKGAKADEQEYVYKEPSAIKKVLYSIATWLLYNIFHCFFR EIKGRGSYKVPQQG-PVIFVAAPHANQFVDPVILMGEVKK----------SLNRRVSFLV AENSLK-QPAIGFLASFFMAIGVVRPQDNLKPARGTIRV---DPE-DYKKLIGHDT---- ---HFL-TDCAPRGLIALPK-SIG----FVEIQSIESDTCLTLRKEFKMAKT-------- -------------EVKNTLLNGTVYKYADKVNQSCVYHRVFEHLAHNNCIGIFPEGGSHD RTDLLPLKAGVAIMALGCMD--KHPDAN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIDIPKELVAKYH-NPETNRDAVKELLDTISKGLQSVTVTCSDYETLMVVQ AIRRLYMTQF---------------ASKLPLPLIVEMNRRMVKGYEFYRNEPEIAELTKD IMSYNAALRHYNLPDHLVEEA----KVNFARNLGLVFFRLIGLSILFALAMPGIIMFSPV FILAKKISQDKARTALSRSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYFLRGQP ----------------WNK-IYIFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSL- -TSPKG----LQKLQKDRGILAEKIIEVVNNFGSELFP-DFDSAALREEF---------- -------------DVLDEEEEDRKTSE----------LKRRKMLKKQKIKRQEKDLSS-- ----------FSDKNDHDDIYEHH-QDSDGV--SLVNSDNSLSNIPLFSTTFQRKSEIS- ----------------------LASTSVAP----------------------------SS S----S-------EFEIE-------DEIL---------EEK--KGLASKIA----QAVLN K--------RIDEDAA------------REEEEKED----------------- >Candidaglabrata_CAGL0E02849g MDKP---------------------------------------LLSEKE----------- -------------KGASKDSSSLQPEKVKDYQYEEASFISKFIYDVILFLLSKILGCFFR EIRSRGSFKVPRNG-PVIFVAAPHANQFVDPVVLMSLAKK----------LSNRRISFLI AEKSLQ-HPAIGFLARRAMAIGVVRAQDNLATAQGKITV---DPD-NYKKIIGHGT---- ---QFT-KDFKPKGLIGLPR-SLG----HVEIQSIESDTELTLRKEFKMNKT-------- -------------EVKHILTKGTSYKYAGKVDQSVVYHRVFEHLAHNECIGIFPEGGSHD RTDLLPLKAGVAIMALGCMA--QHPNTN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIEIPTELIEKYK-NPSTNKEAVKELLDTISDGLQSVTVTSQDYETLMVVQ AMRRLYSGQF---------------HQKLPLPLVVEMNRRLVKGYETFKDDPEIVQLKTD IMAYNAHLSQFNLPDHLVEHT----KINVARNLGLLVFRSLRLTIMITLSLPGLILFSPV FVIARKISNDKKRAALASSTVKIKANDVVATWKILMSMGVAPILYVLWSSLATYYLRHKD ----------------ISK-VIIFILSYLACAIVTYSALVVGDIGMDIFKSLKPLYISI- -TTPQG----LKRLQVERRQLAKRITEVVNNFGSVLFP-DFDYKALSEEY---------- --------------AVDEEEEERKTAE----------LRRRRIIKRQKERENARGI---- ---------------SDKNDYDDQTQDSDAI--SLVNSDNSLSNIPIFSSALGGKSEAS- -----------------------STYSLLP----------------------------SS STVSES-------DAEME--------QES---------KEP--SALSQKIT----AAMFS K--------RNENE--------------------------------------- >Kazachstaniaafricana_XP_003959018 MEKP---------------------------------------LSA-------------- -------------KKVEQHDPSFVKDDKCDIGYEEPSKIRKYIYDCILWILSTTIRCFFR EIRTRGGFKIPKEG-PVIFVAAPHANQFIDPVILMDQVKL----------TVDRRVSFLI AESSLK-QMAIGFFARCVMAIGVVRPQDNLKFIEGKVTI---DPS-DNRKIIGHGT---- ---HFL-RDCKPKGLIGLSKASLG----FVEIQSIESDTELTVRKEFKMNKP-------- -------------SVKHALSKGSIFKYASKVDQSLVYHKVFEHLANNGSIGIFPEGGSHD RTDLLPLKAGVAIMALGCMN--KHPDVN---------------VKIVPCGMNYFHAHKFR SRCVIEFGDPIEISKDLVAKYH-NPETNREAVKTLLDTITEGLKSVTVTCPDYETLMVVQ AMRRLYSTQF---------------SGKLPLSLVVEMNRRLVKGYETFKDDDELIQLKKS ILTYNSHLSHYNIPDHLVETA----KINFMKNLSLLIFRSIRITLLLVLALPGIIMFSPV FILSKRISEQKARTALAKSLVKIKANDVVATWKVLISMGFAPLLYIFWSVLVTYYFRESP ----------------IGN-VLTFLVSYLLCATVTYSALLVGDIGMDILKSLRPLYLSL- -TSPNG----FKELQKERRLLTAQIVDTVNSFSSDALP-DFEEEILFNQG---------- --------------TINEEEEDRKTSE----------LKRRRLLRKKKKEREQRMAQQ-- -------------EEEEAAGEHEHAQESDAI--SLVNSDNSLSNIPLFSNTSGYKSESS- ----------------------LTSYPVSR----------------------------DS T----S-------GFESDI-----SVEKI---------VSK--GAITSKIA----EAILR E--------RNKAE---------------EENQE------------------- >Naumovozymacastellii_XP_003675136 MDKP---------------------------------------LIPESRKS--------- -------RKATR-SSPTKPSKRSSSPPFEAYKFEEPSTFRKFAYDAILFFLTSIFHCFFR EIRSRNSYKIPSSG-PIIFVAAPHANQFVDPVILMEQVNK----------QVNRRVSFLI AEKSLH-EAAIGFFARCVMAIGVVRPQDKLKLATGKITI---DPE-NPRRVIGQGT---- ---KFL-QDFKPRGLIGLPK-SLG----NAEIQSIESDTSLTLRKEFKTIKP-------- -------------EVKRLLTKGTTFKYADKVNQSLVYHKVFEHLANNDCIGIFPEGGSHD RTDLLPIKAGVAIMALGCMD--KHPDVN---------------VKIVPCGMNYFHPHKFR SRGVVEFGDPIEIPRELVEKYH-NSETNKEAVKELLDTITEGLRAVTVTCVDYETLVVVQ AMRRLYCTQF---------------SSKLPLQLVVEMNRRLIKGFETYQDDPKLIQLRKD IMEYNAHLRHYNIPDHLVETA----KYNFAKNLGLLVYRTVFISIAFILSLPGIIMFSPV FILANRISKRKAREALAGSTVKIKANDVIATWKILIGMGFAPLFYNIWSILITYYFRHSA ----------------VTK-KFIFIVSYICCVLVTYSALIVGDIGMDIFKSLRPLYLSL- -TSPRG----LRELQKERESLTVRIIEVVNTFGPDLFP-GFDGEEFTNEF---------- --------------TIDEEAEDRKTME----------LKRRRLVRKRKAKEQNRKHEL-- ----------------LSETDDERVTESDAV--SLVNSDNSLSNIPIFSSMSGIRSETS- ----------------------ISRSN-------------------------------SS I----S-------DFESD-------EDAL---------IGK--SDLAGKIA----QAVMN R--------RADVD---------------EE--------------IGG----- >Lachanceathermotolerans_KLTH0E07458g MSEG---------------------------------------LASQEL----------- -------------ESVSKTADSRANQEKDAYAYEEAPAYRKFVYDVFLWLLSNIFDCFFR EIRSRGRYKIPTQG-PVIFVAAPHANQFIDPVILMGQVKK----------AVNKRISFLV AEKSLT-RKAVGTFARCAMSIGVGRAQDNLRPAPGKIRV---SEE-NPRKIIGQGT---- ---KFT-NGFTPQGLIGLPK-SLG----NATIESIESDTVLYLRKEFKQNKP-------- -------------EVRQLLVKGTSFKYAPKVDQKKVYERVFEHLAHDQCVGIFPEGGSHD RTDLLPLKAGVAIMALGCMS--KNPDVN---------------VKIVPCGMNYFHPHKFR SRAVVEFGNPIEISPELVQKYQ-QSETNRDAVRELLDTISDGLKAVTVTCPDYETLMVVQ AARRLYAGQL---------------SAKLPLSLVIEMNRRLVKGYQTYREDPRIQELKEY VLKYNANLRHFNIPDHQVESA----KINFAKNFGLLIFRSLRLLFSLILALPGIIMFSPI FIIAKIISQNKARQALAASTVKIKANDVIATWKILIGMGLAPLLYSVWSGLLTYYFRHSI ---------------TRNK-FVSFAGIYVLCSIVTYSALIIGDNGMDVFKSLRPLYLSV- -TTPGI----LKDLQKERRGLEQKITEIINTLGPELYP-GFDGTSLSDKY---------- ---------RYGLTSYDEEEEDRKTSE----------LKRRRLLRKRKESGKQKARRS-- ---------------------PESEAESDAL--SMLNSDNSLSNIPIFSNVDRRSGSVS- ---------------------SMTSLS--------------------------------- -----S-------GFEIV--------EDM---------TKP--DELSGKIA----HAVRE K--------RE------------------------------------------ >Zygosaccharomycesrouxii_ZYRO0G09834g MMPVDEKTTGGSSTT---------------GFSTTSGDTE---LIARDLEP--------- ------ATSPSS-KSSTNEEKEDKDKGNEAHPHKQP-FYRILIYNIILGMLLNIFDCFFR EIRTRGGYKVPRQG-PVIFVAAPHANQFVDPVILMGQVKK----------VVNRRISFLV AEKSLK-RRAIGFFSRCVMSIGVVRAQDNLKPAKGKITI---DPE-NPRKLIGHGT---- ---SFL-TDFKPKGLIGLPK-SLG----NVEIDSIESETELTLRKEFKMNKP-------- -------------EVKSILTKGTSFKYADKVNQSLVYHKVFEHLASNQCIGIFPEGGSHD RTDLLPLKAGVAIMALGCMD--KHPESN---------------VKIVPCGMNYFHPHKFR SRAVVEFGNPISIPHELVEKYR-SPETNREAVKEMLDTISEGLKAVTVTCSDYETLIVVQ AMRRLYAGHL---------------SSRLPLSMVVEMNRRLVKGYQTYREDPRIISLKKE IMTYNAHLSHYNIPDHLVMRD----RMSFAKNLWLLCFRSLRLLVMLAFALPGIIMFLPI FIVAKRISKQKAREALAASTVKIKANDVIATWKILIGMGLAPLLYTLWSIMISYLLRHRF ---------------PGNK-ILTFVISYFACSAVTYSALLVGDIGMDIFKSLRPLYLSI- -TTPQG----LRDLQKERHALAEKITELINTIGPELFP-DFDADTLRHKY---------- --------------ELDDEEEDRRTAE----------LKRRRLLKKQKIKHEVKRAER-- -AKT---------AEREENENDGHSTDSDAV--SLVNSENSLSNIPIFSNPANLISEGS- ----------------------TSSADM------------------------------SS G----S-------EFAVE--------EKI---------GAK--DGVSSKIV----QAIWE K--------RSVEDHE------------GNNHDDADDSE-------------- >Kluyveromyceslactis_KLLA0B10538g METP---------------------------------------LIKKQPVP--------- -------------LEPHETPHVHDDPDEPPFQYEEPSFFRKAIYDVFLWLFTKIFDCFFR EIRTRGGYKVPTQG-PIIFVAAPHANQFVDPVILMGQVKK----------TVNKRVSFIV AEKSLR-RPAVGTFARCAMSIGVVRAQDNLKPAKGKIRI---DPD-NYKRLIGVNT---- ---EFT--KYHQKGLIGLPK-SLG----NVEIDSIVSDTELFLRKEFKMQKP-------- -------------EVKSTLLNGTSFKYAAKVNQSRVYHNVFEHLAHDQSIGIFPEGGSHD RTDLLPLKAGVAIMALGCMD--VHPDVN---------------VKIVPCGMNYFHPHKFR SRAVVEFGHPIEISRELVDKYR-DPATNREAVKELLDTVSEGLKAVTVTCPDYETLMVVQ AIRRLYAGHL---------------VSKLPLPLVVEMNRRIVNGFQTLKDDKVIVKLKED ILKYNAHLRDYNLPDHQVETA----KVNLIQSLGLLIWRSVKLVVLLILSLPGIILFSPV FILAKSISKKKAKEALAASTVKVKANDVIATWKILIGIGVAPLLYSLWSLLFVWYFKESL ---------------TKNK-FISFIFAYTCCATVTYSALIIGDHGMDIFKSIRPLYLAV- -TSPKG----LQSLKDERTVLSEKINEIVNEYGPRLFP-DFNVETFASYATG-------- ---------HSSTDEQLEEQEDRKTME----------LKRRRRLAKLKKRFKEQEEKQ-- DADSSAPTSAKPESASTTTTAATTDDESDAI--SMINSDNSLSNIPIFSNRERSTSSTS- ----------------------IGSLG--------------------------------- -----S-------SIELA-------ANPD---------EER--NHSISGIA----DQVRR K--------RLD----------------------------------------- >Eremotheciumgossypii_NP_986036 MDTL---------------------------------------LASKKTQGEC------- --AEEGANSAAT-GSTVSAGIYGSENEQTSYEYREPAWWRKALYDLFLWIFIRVFDGFFR EVRTRNGYRVPRHG-PIIFVAAPHANQFVDPVVLMGQVKQ----------TVGRRVSFLV AAKSLT-RRAVGTFARCAMSIGVMRAQDNLQSAPGRIRV---DPS-NPRRLLGEGT---- ---RFT--AFQEKGLIGLPK-SLG----NVDIESIQSDTELTLRKEFKMQKP-------- -------------EVRSLLEHGTSFKYAAKVDQSQVYHRVFEHLAHNQCIGIFPEGGSHD RTDLLPLKAGVAIMALGCMH--IHPDVN---------------VKIVPCGLNYFHPHKFR SRAVVEFGTPIEIPPHLVAKYG-NPTTNKEAVKELLDTITEGLKAVTLTCSDYETLMVIQ ATRRLYAGHL---------------SSKLPLPLVVEMNRRLLKGYEAFKDDPRIKRLKED IMVYNDHLRQYNIPDHQVETA----RLNLSRNIGLLISRSLRLLFIGMLALPGVVMFSPV FILAKHISKKKAQEALSASTVKIKAKDVVATWKILISIGVAPALYIFWSLLFVWYLRDSY ---------------TKDRFLVSFVVAYLCSCILTYSALLAGDIGMDIFKSLRPLYLSL- -TTPKG----LQSLQEERCVLAERITELVNLLGPQLFP-DFDAELLKKKY---------- ----------FATSVSLEDEEDRKTQE----------LKRRRLLRKKKEAAAMVPSPI-- -------------QATDSDEITVADDESDAV--SMVNSDNSLSNIPLFSSVHRSESASS- ----------------------VSTMS--------------------------------- -----S-------TFNYDF-----D-------------VKQ--GNIGGKII----DAVRQ N--------RKEE---------------------------------------- >Vanderwaltozymapolyspora_XP_001644985 MTKA---------------------------------------DVA-------------- -------------KAKDSKSSKGAHDADLEDVYEEPPFHRTLIYDFVLWLLINIFNCFFR EIRSRGGYKIPKQG-PVIFVAAPHANQFVDPVILVGQIRK----------SVNQRISFLI AAKSLK-MKVVGFLARCIMSIGVVRPQDNLKSARGKISL---DPE-NPLKINGQGT---- ---KFL-EDVQPRGLLGLPK-SLG----FVEIQTIESDTVLYIRKEFKTSKP-------- -------------EIKSLLTKGCSFKFAPKVDQSKVYHQVFEHLNHKGSIGIFPEGGSHD RPDLLPLKAGVAIMALGCMD--KHAEAN---------------VKIVPCGMNYFHPHKFR SRAVVEFGDPIEIPRELVVKYG-NPETNKEAVKELLDTVTEGLKAVTVNTPDYETLMVVQ AMRRLYTAQL---------------NTKLSLPMIVEMNRRIVKYYQTYKDDPEFRQLKND ILKYNSHLQQFNIPDHLVETA----KVDFTKNLCLLVFRSITLFVSVILALPGILLFSPI FLVSKRISEKKARQALANSTVKITAKDVVATWKILMAMVFAPLLYIFWSLLFTLYYGGSH -----------------NK-ILTFCISYVTCSLVTYSALIIGDMGMDTFKSLRPLYISL- -TSPKG----LKKLQKERLELSDRITEVMNTLGAELFM-DIDTHIYEDE----------- ---------------IDEEAEDRKTAE----------LKRRRMLRKKKEKLQKMKLEN-- -------------ISSENTSEVEQTQESDAI--SLMNSDNSLSNIPFFSTGVDRPSSSA- ------------------------SSVMAE----------------------------SS S----S-------DFEVE--------NFE---------SKG--NNISDKIA----KAIWE K--------RHGEK---------------EE---------------------- >Candidaalbicans_XP_710056 M----------------------------------------------------------- ---------------------APSSSSSLDLHYERPKWYRLAIYDTLLWLLSVIFDCFFR EIRPRGAFKIPREG-PVIFVAAPHHNQFVDPVLLMNQIKK----------EANRRISFLI AAKSYK-LKAVGTMAKCQLSIPVVRPQDCLVKGTGKIFV---DFDKDPLRVTGKDT---- ---KFT-KECMVKGLIALPQ-SLG----ASEIVEIISDTELVIRKEFKSSD--------- -------------KVKVLLTNGTAYKRADKIDQKQVYQMVFDHLLDDGCIGIFPEGGSHD RPDLLPLKAGVAVMALGAMD--KNPGCN---------------IKIVPCGMNYFNAHKFR SRAVVEFGDPIEIPKELVKKYA-NPETNREAVKELLDTITTGLKAVTVTCEDYETLMLIH AVRRLYAGNF---------------AQQLPLPLIVEMNRRLVIGYQHFKNVPKVQEIKEK VLHYNDFLKTLYLPDHDVESCN--DEAHKITLIPIFFFRVFKLLILFILALPGATLFSPV FLSTKIISKKKAKEALANSVVKIQANDVVATWKILVSMGIAPIVYSFYASVGTYYCSTHD --------YFS----HWKL-FWVWIFLYSCGVLVTYSALITGEQGMDLFKSIRPLYLSI- -TSGSS----IKELKKMRHELSEEITELVNHYGPQLFPNDFNLLDLQKSLNIN------- ---------GDVVYADSDEEEDMKTEE----------LRNRRIARRKAEKKKKQTQENED T------------QELQSSDMKHSSSMSDGI--SLLNSDNSLTNLPMFSDYVLHKNAKNP DLQLDPQSHYGSRVNSNLNSGANSSVSIYDDYRFASQSEHGGTASPVRYSRLPHLPETSS S----D-------HMELNF---ASKPE-----------GQK--MRLRDRIK----TKLRE N--------RKEN---------------------------------------- >Debaryomyceshansenii_DEHA2A08624g MPYVGKGLLHSRRQTLIGCEDEIGATTMTNAHSSSEDAGE--ALLQSNGQANLSDKVNMD LNDDNGNKASRGRKASASGDSFVRNKEMDEFEHRQRQWYRMVIFDLVLWMFSVVCDCFFR EIRPRGAFRLPRQG-PVIFVAAPHANQFVDPIILMGQVRK----------EAQRRVSFLI AAKSYK-QRIIGFLSRCQFSIPVIRAQDNLKKATGKIFI---DVESDPCRVTGKNT---- ---KFL-SECAVRGMLALPQ-SLG----ASEISEIISDTELVIRKEFKRTD--------- -------------QITTLLKNGTSFKSADRIDQKKVYQIVFRHLSLGNCIGIFPEGGSHD RTDLLPLKAGVAIMALGAME--YNPDCN---------------VKIVPCGMNYFNAHKFR SRAVIEFGHPIDIPKELVKKYS-NPETNRESVKELLDLITTGLKAVTVTCEDYETLMVVQ AARRLYAGNF---------------VQFLPLPLVVEMNRRLVLGYQTFRNEEQIKNLKEK IIIYNNQLKQLYLPDHHVEAC---DESHKLRVLPILLFRIVKLFLLMLLALPGATLFSPV FICTKWYSTRKAKTALANSTVKIKANDVVATWKILISMGIAPLVYSFYASIGTWYCHRYK --------KFED--WNVSL-FFVWFILYMLGVIVTYSALLTGEQGMDIFKSIRPLYLSI- -TSGSS----IKDLKKLRNELSEEITYVVNHFGPDLFPNDFNLLKLKEHLKIS------- ---------DNVDYVDSDEEEERKTQE----------VRKRRMKNRKAARRKQASDDS-- -------------ISGLSLDEKNSSSVSDGI--SLMNSDNSLTNIPMFSDYHLHMNAKNP DIKIEQQSVV------------HSSASIADDFNYKVHNSPAGKPS---------VSRYDS N----S-------HIELNF---GNLKEEQ---------PSK--SKLSDKIK----YKIRE S--------RDKAAGN------------------------------------- >Meyerozymaguilliermondii_EDK39427 ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------MNQVKR----------EANRRISFLI AAKSYR-QKFIGHFSRVQQSIPVVRAQDNLKPGRGKIKI---DLDNDRLLVIGTGT---- ---KFT-EDCSPKGIIALPQ-SLG----ASEVVEVRSDTELVIRKEFKDTQ--------- -------------QIRTLLTKGTSFKAAHKVDQKEVYERVFEHLSHGNCIGIFPEGGSHD RTDLLPLKAGVAIMALGAMQ--HDPGCN---------------VTIVPCGMNYFNAHKFR SRAVVEFGHPIEIPRELVKKYS-NPSTNRESVKELLEIITTGLKAVTVTCEDYETLMMVQ AARRLYAGNF---------------AQYLPIPLVVEMNRRLVLGYQTYKNEKTIQDIREK VIKYNKLLSSLYLPDHHVEEC---DESNKLRVLPIFLFRIFKMIFLFLLALPGSILFSPV FICSKIVSGRKRATALANSTVKIRGRDVIATWKILIAMGVAPLVYSFYATVGTIYCYFYG --------IL-----HYKL-VSIWFALYMLGVLVTYAALLVGEQGVDLLKSMRPLYLSL- -TSGSS----IRELKIMRKELAEEITNLVNHYGPELFPDDFNLLHIRDKLY--------- ---------ANEGYIDSDEEEERKTQE----------LRNRRMRNRKAAKKHKAAATK-- TMELKSESSSSINDTELSLQDEEVSSISDGI--SYVNSENSLSNIPLFSDYHLHMNASNP DLQLEAQSNF------------HSTASMADDYNSRNMDNR--------------PAYSRN N----S-------HLELNF---ANAKHRREPSDALRT-TQK--MKLSDKIK----NQVRQ G--------RTQGE------------T-------------------------- >Millerozymafarinosa_PISO0F06935g MTQVSSGYEAERPEA-----------SMQKEHGEHGEAGEHTGLLEAEKKS--------- ------AETATA-DAAAHQRKTPKQSIDHKLEYEEPGWFRKFTYDLLLWLWSVIFDCFFR EIRPRGAFKLPRKG-PLIFVAAPHANQFVDPIILMNQVKR----------ESGRRISFLI AAKSYK-QRFIGFFSRCQMSIPVVRAQDNLEPGSGKIRI---DMDTDRLLVKGEGT---- ---KFT-EECMEGGLLSLPH-SLG----ATQIMDIISDTELTIRKEFKDTA--------- -------------KIRDLLKKGTSYKRADKVNQNSVYQLVFKNLSKGHCIGIFPEGGSHD RTDLLPLKAGVAIMALGAME--HYPDCN---------------IKIVPCGMNYFNAHKFR SRAVIEFGDPIEISRDLVARYS-NPDTNREAVKELLDTVTDGLKAVTVTCTDYETLMVVQ AARRLYSGNL---------------SQYLPLPLVVEMNRRLVLGYQTFKNEESVKKLKEK ILKYNDKLKHLYLPDHHVEDC---DETHKLRVVPILVLRIMKLIFLMLCALPGAILFSPV FFLSKRISQQKQKTALANSTVKIKGNDVVATWKILISLGFAPLLYSFYATIGTIYCYKNE --------TF-----QINL-LFVWFFIYMCGVLVTYAALITGEQGMDLFKSIRPLYLSL- -VSGSS----IREVKNMRNELSEEITYLVNQYGPQLFPNDFNLYDLQKKR-LS------- ---------ADGELIDSEEEEDIKTAA----------LKERRNKSRKASRATKIAQEAVD TDEGKETSEGNESSSELSLRSNHSDSVSDGI--SLMNSDNSLTDIPMFSDYHLHKNAKNP DVLLDT----------------DSSTSLRDQANFKEYSN--GTQDTARNG----MSRSSS S----S-------QIEFNF---VSTKDKKHSEN-----NDG--TKLSHRIK----NKIME G--------RERPN--------------------------------------- >Millerozymafarinosa_PISO0E05614g MTQVSSGYVAEGSEA-----------VIQKEHDEHGEAGEHTRLLAAEKVS--------- ------AETAAA-DAAAHKRQTPKQSIDHKLEYEEPGWFRKFTYDLLLWLWSVIFDCFFR EIRPRGAFKLPRKS-PLIFVAAPHANQFADPIVLMNQVKR----------ESGRRISFLI AAKSYK-QRFIGFFSRCQMSIPVVRAQDNLEPGSGKIRI---DMDADRLLVKGEGT---- ---KFT-EECMEGGLLSLPR-SLG----ATQIMDIISDTELTIRKEFKDTA--------- -------------KIRDLLNKGTTYKRADKVNQNSVYQLVFKNLSKGHCIGIFPEGGSHD RTDLLPLKAGVAIMALGAME--HYPDCN---------------IKIVPCGMNYFNAHKFR SRAVVEFGDPIEISRELVERYS-NPETNREAVKELLDTVSDGLKAVTVTCTDYETLMVVQ AARRLYSGNF---------------SQYLPLPLVVEMNRRLVLGYQTFKNEESVKTLKEK ILKYNDKLKHLYLPDHHVEDC---DETHKLRVVPILVLRIMKLIFLMLCALPGAVLFSPV FFLSKRISQQKQKTALANSTVKIKGNDVVATWKILISLGFAPLLYSFYATIGTIYCYKNE --------TF-----QINL-FFVWFFIYMCGVLVTYAALITGEQGMDLFKSIRPLYLSL- -VSGSS----IREVKNMRNELSEEITYLVNQYGPQLFPNDFNLYDLQRKP-LS------- ---------ADGELIDSEEEEDLKTTA----------LKERRNKNRKASKATKIAQEAVE TEEGKENSEGNESSSELSLRSTHSDSVSDGI--SLMNSDNSLTDIPMFSDYHLHKNAKNP DVLLDT----------------DSSTSLKDQANFKEYSN--GTQDTARNG----MSRSSS S----S-------QIEFNF---VSTKDRKHSEQ-----NDG--TKLSHRIK----NKIME G--------RERPN--------------------------------------- >Komagataellapastoris_XP_002492283 MAEA-------------------------------------------------------- ---GSQPDSTQS-DKPWPEVSSATADSESEEVYVEVSWIRKLIYDIVLWSFCVVFDCFFR EIRSRGSFNLPRSG-PTIFVGAPHANQFVDPIILMGQVQQ----------RAGRRISFLV AEKSHR-RKFIGLISRSQMAIPVSRAQDNLKGGRGKIRR---DSE-NPLRIVGEDT---- ---YFT-QDCANQRMLALPN-SLG----TSEIGEVVSDTELILKKEFRHPST-------- ------EA---EEKANRILAEGTSYKLAPKIDQSIVYKKVFQHLAHGNSIGIFPEGGSHD RTDLLPLKAGVAIMALGAMS--SDKSCK---------------VKIVPCGMNYFHPHKFR SRAMVEFGRPIEISDELVSMYE-NKETTKDAIKEVLRIITKGLKSVTVTCPDYETLVCIQ TARRLYSNNF---------------SSRLSLESILEMNRRLVKGYEHFQNEPRIQELKEK ILAYHEVLRLSGIPDHKVNDY---RPEKRLQTFAELLGNLFQFALLGLLALPGALLFFPV FVATRKISAKKAKEALAASTVKIKAIDVVATWKILVSLGFAPLLYIFYSTVGTYIIRSRY --------YIEP--GFGKT-AFTFFGFYILSATITYSALIVGDIGMDSFKRLKPLWLFL- -TDSET----LSNLKKERQELSLEITEVVNEFGPQLFS-DFNLLDYQKKVESKRKKKRSE KYRKKAFEVSSMGLDSSDEEEELKTQD----------VRRRRAARKQAASTT-------- ------------------------EAPSNRF--DNKSTGINISNVPIFSNDLYGGTSSAP TTD-------------------VSSIS--------------------------------- -----S-------ELSSDY--QSSDGENE---------NDD--SQLKDRIR----DRIHD S--------RHD----------------------------------------- >Ogataeaparapolymorpha_YBL011W_ESW99553 M----------------------------------------------------------- ---------------------------SSSSNWQEPSWFRKLVYDLVLWTFTVIFDCFFR EIRPRGAFRLPKSG-PIIFVAAPHANQFVDPIVLMGQVKN----------ETGRRISFLI AEKSHK-RKFIGLISRSQMSIPVRRAQDCLKPAAGSIKI---DPE-NEFHVFGVDT---- ---QFT-KVCQTKGLLALPN-SWG----TAEVGEIVSDTELYLRKPFKFSSP-------- ------KT---ADEAKKALESGTAFKTAPRIDQSEVYHKVFEHLAHGHCLGLFSEGGSHD RPDLLPLKAGVAVMALGAME--AHPGCN---------------VKIVPCGMNYFHPHKFR SRAVVEFGMPIEISPELVAKYS-NPETSKDAIKELLETITGGLKAVTVTCPDYESLTCVQ VARRLYSNNM---------------SKHLSLQSIIEMNRRLLKGYLHYKDEPRIMELKKS ILEYNEKLRIFKIPDHLVEGD---RNDDTLTIFTRFVTSLVQLVVLGALALPGVILFSPV FIATKVISEKKRREALAASTVKIMARDVIATWKILVSIGFAPLLYIFYSVLGTMLMRKYY --------VLS----DRSA-FTIFCSIYLFSAMITYSALIFGDKGMDLLKSIRPLWLAL- -VNKEG----LTQLRETRRQLSMEITEVINEYGPQLFP-DFNLYDYEKKLELKRLRRQE- --RKKLQLEQLENMDSEDEYEEAKTQR----------LRKRRAAKRQEREQS-------- ------------------------GIYAQAN--ESLKAKLT-SSVPIISNDNDNNSSVG- ----------------------LSSSSETDF--------------------------ASS G----S-------EYEPDN---------------------D--SASASKIGLVRDTMIRE N--------RERNEKN-------------EE---------------------- >Yarrowialipolytica_YALI0C00209g MSETDH-------------------------------------LLA-------------- -------------AEPVAEYPQYTPWPNSRKSVDTEFSATSWIYDLVLWIFTACFDIFFR EIRPRGAFRIPRKG-PVLFVAAPHANQFVDPVILMNQVKQ----------EAGRRISFLV AEKSMR-RAAVGRMARSMNSIPVVRAQDNAKKGEGKIYV---DAE-DPTKIHGIGT---- ---QFT-KQCEVRGLVVCSS-SVG----SIDVAEIVSDTLLIARKEFKGPKA-------- ------------KEALKESNGGITYKYADYVNQATVYRSVFDKLHHGGCVGIFPEGGSHD RTELLPLKAGVAIMALGALA--EDPSCG---------------VRIVPCGLNYFHAHKFR SRAVVEFGSPIAIPPDLVEKYKAGGEAKREAVKTVLDITAAGLKSVTVQVQDFDTLMLIQ AIRRLYRPP----------------GKKIPLPMVVELNRRLVYAYNHYKDDPRIEEMKQE IRKYNKFLQAMGLKDHQVEKA----RISKIEILGRLLYRSIKLVFLSIGCLPGLLLFSPI FIISKSISKTKAKEALKASSVKIKANDVVATWKVLVAMGLTPVLYILYSLVGSVVIRKLD --------LIS----WFPT-ILLPGLVLSIIITTSYAALAMGEAGMDIFKSLRPLALALN PSTKNS----LLKLQNERKRLVLKSSELVTSLGPELFP-DFPENSILQG----------- ----------------SDKFEDEENYE----------NEKRSHSRSTSATSLSAMSEG-- --DGDELVREVRKGASYFPVSTISEDEDQAI--SRVGSEASLADIPLFGMSRSQSGAS-- ----------------------LSEASTHG------------------------------ -----S----------------STGADAE---------EAK--TEVTRRIA----LAMEE K--------RREQD---------------EE---------------------- >Geotrichumcandidum_GECA03s02265g ML---------------------------------------------------------- -------------------SKSEAAVPKDKQSIDTISSFITVVYDLVIWVLSSIFDLFFR EIRPRGAYRIPRNG-PLIFVAAPHANQFVDPILVMRQVLV----------NAGRRISFLV AEKSLK-RKFVGSLAKAAMSIGVVRAQDNLKLAKGKIYV---DFEKDPLLVIGEGT---- ---EFT-KQAMVGGLLGLPN-SVG----NSEVAEIRSDTEIVLRKEFRGS---------- -------------KSRKLLEKGTIYKTADHVNQTQVYRNVFKRMDQGGCVGIFPEGGSHD RSDLLPLKAGVAVMALGALA--EFPDCG---------------VKIVPVGMNYFNPHKFR SRAVIEFGTPIDIPPELVEKYKAGGDLKREAVSTVLDIVTDGLKSVTVRCSDWDTLMTIQ AARRLYRPS----------------GKKIPLALVVELNRRLLEGYLHYQDNPAIIKLRDN VASYNKELQHMGLKDHQVETA----SLSKLTILGKLLYRSAKLIVLSFAALPGTILFAPV FFASRTISKQKAAEALRGSTVKIHANDVLATWKLLVAMGLAPVLYTLYAIIAAVIASKYN --------WFP----NIPS-ILLVLILIPAVSSISYSALIIGETGMDIFKSLRPLALSLS PSHQNA----LSDLQKQRRDLVVEVTEVVHSLGPELYP-DFNKYDITKPL---------- -------------------PVDEGSAR----------ASRPSFDRRS------------- ---------------------STSSTESRAL--SRVNSASSLANIPLFGFRRSNSQGS-- ----------------------ISSAVSSV--------------------------RSRS S----S-------GVSIADG-GATSASGV---------QKSFHSEVSQRIK----GAMAE RAQ------AREDG---------------EEEDIESDQN-------------- >Neurosporacrassa_XP_958638 MAEQSQQLNGHAPES----------------HQHPNGNAETTPLLSTDLQQ--------- -------------QHEGKDASAPPQSAKSPSASKELYPMSNWKYDTFLWTMSFLVDTFFR EVHPRGSWKVPRSG-PVLFVAAPHANQFVDALVLQRTLRN----------EAKRRVSLLI AQKSVK--GFIGWASRQVGSVPVGRPQDSAKPAEGTIYL--PDPIDDPTLIRGVGT---- ---NFE-KQAEVGGIIFLPS-IKGQSGSNVEIVEIHGPEEIRIKRPVNSKLALYQLTGRD DIDEHGELQNKEVKGIKDGYQGTKFKIAPHIDQTKVYQAVFDRLKNGGCVGIFPEGGSHD RSELLPLKAGVAIMALGTLA--EAPDCG---------------LKIVPVGMNYFHPHKFR SRAVLEFGAPFEVPKELVEMYG-IKDKRRAAISKLLDMVHQSLSAVTVSAPDYDTLMVIQ AARRLYNPA----------------GKKLPLPIVVELNRRLALGYDKYKDDPRIIELQKS VAEYNKQLRYLNIRDHQVQYA----KLSWPKVVITFFYRVAKLLVLSAGVLPGLILFAPV FIATKRISHQKAKEALAGSTVKIQGKDVIATWKMLVAMAVAPILYNLYTCLLAYMVGKHR L-----WGYVPE---WVPI-WLVYFFGWVFFPAITFAALRFGEVGMDILKSLRPLALCIS PTSSYS----LQSLKQRREELSAQVTHLINTLGPEMFP-DFEHIRLVAA----------- ----------DGSSRIHADGTVSPTQP----------FKRRDSGVSSPPISTPGIST--- --PGT--------ESPHGLRRTGTTSSSRNI--PRNESFSNIGQVPMFATRPPSRSRSR- ----------------------SSSAGGGGG----------------------------- -----N----------VQFG-GPLGGSPVDKFPNLN--TEEGFNEASKKIR----EAMRE RGEMR----RRKSQGKVYTFSEQ---SVDEEVEDEVSTGSSVD--EDGKK-HL >Aspergillusfumigatus_XP_751693 MGKKQPY----------------------------------------------------- -----------------------------------IPPLIGWLYDLVLWSFSVLIDLFFR EVHPRGSWKIPRRG-PLILVAAPHANQFVDSLILMRVLRN----------EAHRRISWLI AEKSFK-RKFIGLLARGIGTVPVARAMDNVKPGVGTIYL--PDPVNQPTLLRGVGT---- ---NFEGPEFEKEGTISLPT-INGTSH-SAAIAEIRGPEELVLKKPFKAKDALFQLTGRH DITDDGTFTG-DGSAKDPDFQGSKFKVSPHVDQTAVYQAVFGRLNAGGCVGIFPEGGSHD RPNLLPLKAGVALMALGTLA--DNPDCG---------------LKIVPCGMNYFHAHKFR SRAVIEFGNPIEVPREVVDQFK--RGEKREAVGALLDTIYQGLVSVTVTSPDYETLMVIQ AARRLYNTK----------------GKNLPLPMVVELNRRLVKGYTHYKDDPRVIHLRKA VADYNKQLRLLGIRDHQVEYA----KFSWIQVIATLIYRLGKLALLTIGTLPGLILFAPV FIATKYISKKKSQEALAASTVKLQGRDVMATWKLLVALAFAPAVYAFYTATFTWWAYYNR I-----QGLVPV---WMPL-WLIVPIGMILFPTITFAALRIGEVGMDIVKSLRPLVLSLN PSSANT----LVKLRERRAALAQQVTEVINTLGPELFP-DFDAARIVTDP---------- -------------------------------------FREDHRPAGKTGVDHSAVPEI-- -------------RRTSATDTEVESPTREPL--PRNESFHNLANIGFFSTRPSSRSRSR- ----------------------SGSFGGRPG----------------------------- -----S------------------SGQQLKPLSQVT--TKDGFEEVSSKIR----DAMRE RGERR----RRRSEDGSWDMASSGPGTPSSE---------------GSRK-DL >Schizosaccharomycespombe_NP_596450 MQ---------------------------------------------------------- ---------------------------------------HTFIYDTCLWILSILIDFFFR EVKTRGSFRVPRKG-PLILVAAPHANQFVDPLILMLQLRR----------EVGRRTSILV AAKSYR-QRFIGLMSRAFGAIPVERAQDLAIRGEGKIFV---VAEGDKTAIHGKDT---- ---LFT-KHSVGDTLL-LPN-NYG----SSHIASIKSDTLLYVKREFRGEDA-------- -------------ERVLLSPEGSSYKVAPEIDQTYVYNEVRRRLVKGACIALFPEGGSHD RPEMLPLKAGVAIMALETLS--QHPDCG---------------LQLLPCGMNYFHPHRFR SRAVLEFGSPLSIPTEYVELYK--AKKRREAIQGVLDMIYDALLSVTVQAPDYETLMVIQ ACRRLYKPA----------------HIQFALPKVVDLNRKLIVGYNHFKHDPRVIRLHDK ILLYNRQLYRLGLRDHQVQSL----QYSRFMILYKLVYRCCKLFLLALGALPGAILFSPV FIAAHRISVKKAAAALKASSVKIQGRDILATWKLLVALGMTPILYSFYALLCCYYIYSYK --------LIPH--SSIFV-YTVPIISTFLFPMVTYAALRFGEVAVDIYKSIRPLFLALI PSKANA----VYILKDERKQLVAEVTDLINKLGPELFP-DFDPDRITTT----------- -------------------------------------IEKPERPSRFARRLSS------- -------------SVASDVDNLSQLHDTDLN--SEVSAPAPLQNVYLYSPNPSALPPSD- ------------------------------------------------------------ -----E--------------------------------EEKDINDKAKLIR----NALRQ RMGQRMTEIRSRDTPP-------------EEVFSESDEELSD----------- >Candidaalbicans_XP_715356 MSRD-------------------------------------------------------- --TPDSLSSSL--SSATPHYHPHKHDKKKSMLHYFQLIIRSITYDLVLFFFDCVIHTFFR DIRSTGNFNIPQEG-PVIFVIAPHHNQFVDGLVVMTKVKE----------ISNRRIAFLI AKKSYD-RMVIGQAAKLCGCIPVERAQDFLKLGQGKVFV---DPN-DDCVLIGENT---- ---AFT-KQCQKKGLIGLPN-SLG----NCQIASIEDDTHLTLTKPFGSKNS-------- ------EI---QSRIDKAFRDGTSFKIAPHIDNHVVFENVFNHLNDGNILGIFPEGGSHD RPDLLPLKPGVAIMALGAIA--QQMEECEENDNNGKEQKEIQPISVVPVGLNYFHPNKFR SRVVIEFGKPIVVDQSMGKEYM---EHHRDTVDKLLKVVTFGLKQVTLTCDDYDTLMVLQ AARRLYTSTN---------------REQIPLPMVVEMDRRLIKGYQQYKDEPDVKKLRDA VYHYNRTLMRLNLHDHQVESL---DKFDKLKTFQMFVSRFFKFSLFMGLSLPGIILFSPV FITSKKISVRKAKEALAASSVKIKAKDVISTWKILVALVLAPALYIFYSVIGTYLIVKSQ --------IVP----QLST-IIIFIICYGWAVLTTYASLRVGEIGVDYYKSLKPLFISL- -ISYEKDQLQIRELKKTREELRQRVNLFCNNYGPGMFQ-DYDEFYRNYN----------- --------------------QMETETD----------YDEFKQSHKP------------- ------------------------LRRQNSW-TSMDLTLNNLSDIPIFSAADLEQSND-- ----------------------ISTSESSDE--------------------------VND E----K---------------EVEVEDVG---------DHS--NEVSVRLR----NAIRE R--------RQNSF--------------------------------------- >Debaryomyceshansenii_DEHA2E07040g MDTTNK------------------------------------------------------ --DPEKKEDENG-TRKTVEVENGLLTR----------ILTIISYDLVLWFFSAVIHTFFR EVKSRGTFNIPKKG-AIVFVIAPHANQFIDPIVVMSSVKQ----------YSRRRIAFLV AAKSYR-RKFIGTGAKFTGAIPVERAQDLLRKGTGTIKL--QDLE-DGTIVEGEGT---- ---LFT-KECMKKGLIGLPE-SLG----NAVIESIESDTKLTLRKTFQINVS-------- ---DPKEA---DKRRIQRLTEGTPFKVAPHVDNNCVFQHVFDHLNGGNVLGMFPEGGSHD RPDLLPLKPGVAIMALGAAAKSEDPDAV---------------INVIPVGMNYFHPHKFR SRAVIEFGKPIKVDKKLGKKYE---ENPKDSVAKLIDVITLGLKEVTVTCGDYDTLMALQ AARRLYTSSN---------------RESIPLPLVVEMNRRLVKGYQKYSNDPDVIEMKTL VSNYNKKLMRMGLHDHQVESL---TETNRIHTFVTFAARLFKVFLFLGLSMPGIFLFSPV FIVGRRIARKKAKEALAGSVVKIKANDVLGTWKILVALVLAPSLYIFYSIIGTFLIIKSN --------ITKD---KVPT-VIIFLVCYGWSVLTTYASLRIGEIGVDYYKSLKPLFYSL- -LSHHKDIIQIEDLKRNRTLLAEKVTEFCNSYGPSMFE-DFDRFYRQYNN---------- --------------IESSEYVNESESD----------IENVPVSNTV------------- ------------------------NRPSMSLLRSASFNINNLADVPIFSIPGFSDLQSD- ----------------------VGDDGSKGEH------------------------ESDE S----S-------SFDTS---DIEASDVG------------DLQKSKLRLR----NAMKS K--------FNAENNP------------------------------------- >Meyerozymaguilliermondii_EDK41440 M----------------------------------------------------------- --TPTSPNASNS-AHASTAAENKIATRHRSTLKVVLEVVKVIIYDICLWFFDSIVHTFFR EVKSRGTFHIPRTG-PIIFVIAPHANQFIDPLLVMLKVRH----------YSGRRIAFLT AAKSYR-RKFIGMFARLTGAIPVERAQDLLKAAPGTIKI---DLDGDATVVKGTGT---- ---RFT-RDCQKKGLLGLPD-SLG----NAVVEEVVSDTELRLRKPFQLGKK-------- -----------EQQITDRLTNGTTYKVAPHVDNNVVFQNVFNHLNGGEVLGIFPEGGSHD RPDLLPLKPGVAIMALGAAS--TSPDSH-------------AVINVIPVGMNYFHPHRFR SRAVIEFGKPIRVDKKRSKMYE---DNSKAAVDALLETITLGLREVTVTCTDYDTLMALQ AARRLYTSAR---------------REQIPLPMIVEMNRRLVRGYEKYADNPEVKEMKTM VSEYNKKLMRMGLHDHQVESL---SSSDRFKTLVTFSDRLFKVFLFFGLSLPGIFLFSPV FITARRISRQKAKEALAGSVVKIRARDVLSTWKILVALGLAPALYIFYSVIGTVFLVQSG --------LVP----QVPV-FVVFLVCYGWSVLTTYASLRIGEIGVDYYKSLKPLFYSL- -MSAHKDVGQIEELKKNRAYLAERVTEFCDKFGPGLFS-DYDRFYKRYNG---------- --------------VTDFDEFYDH------------------------------------ ------------------------EEPSSAY---SGFNIHNLADVPIFSG---------- ----------------------EASDSDNGEE------------------------AVGH E----E-------VIPTS-------------------------EKTKLRLR----KAMQE R--------REEEEGN------------GEN---------------------- >Komagataellapastoris_XP_002489418 MT---------------------------------------------------------- -----------------------------------ASGYANFIYDLFAWTFLIIFDIFFR DVKTRGAFNIPSQG-PVILVVAPHSNQFVDPLMVLIQTKK----------STGRRISFLM AAAYYR-KKFIGDLARLTRVIPVERAQDGLKPASGTIHY--ADFEKDPCLIEGTDT---- ---KFT-QECEAKGLIGLPR-SGG----FGKIAEVLSDTLLRLHKPFSSD---------- -------------RAIKIIKGSTTYKTAPKIDNSMVFKHVFDHLHSGGILGIFPEGGSHD RTELLPLQPGVALMALGALA--ENSEQP---------------ITIVPCGLNYFHPNKFR SRAVVEYGSPIVVGEEQARAYK---EDSRKAVAELLKTISTGLKTVTVQCEDYETLMILQ AARRLYQYP----------------KKKIPLPLVVQMNRNLTIGYTKFKDLPEIVHLKNS VQTYNYRLNNLGLKDHQVQTV----KFKPFKAVALLAYRLVKLLILAVLSLPGTVLFSPV FIACKYISHKKAREALANSVVKIRANDVLATWKLMVAMVAAPCLYAFYSTLGTFLIFKYD IA------IVPY--QTKSI-VVTFITAWIILVCTTYAAFRIGEIGMDTLKSMKYLTWSL- -LPSEA----LEELKAERARLSLEVTEVCNNLGPKVIP-EFAKDLEKIE----------- --------------ASNEEQEEEEIED----------EEKEQLLNKT------------- -------------RLGRAPSTSSVNSLRSVT--SSTSMPSELGEVAIFSELPTSSRGS-- ----------------------IRSRSSSL--------------------------SESE T----T-------GLSTG--------------------IEA--KNVRSKIQ----ERIFQ K--------MRNEQ--------------INE-----------------PK--- >Ogataeaparapolymorpha_YKR067W_ESW98880 MQ---------------------------------------------------------- -------------------------------------IVKDLLDELFLWFCHLIIDTFFR EVRVRGSYNLPSKG-ATLVVIAPHHNQFLDAAIVTHAIHK----------INGRRTLFIE AAASIR-RPVIGQLSKWSGAIPVERAQDLLTNKQGKIRY--EDYSNDELTIVGEGT---- ---KFT-TDCEVKGLIGLPE-SAG----NQKIAEIISDTKLRLAKPMTKS---------- -------------KGIEMLIRGTAYKSAPKVDNHDVFKMVFQRLKEGELIGIASEGGSHD RTELLPLKPGVGIMALGTVA--EYEGTE---------------VNIVPCGMNYFHPHKFR SRAVLEFGEPIKVGPEEASAYK---QDPRKTVDALMENITTALKSVTTQSPDLETLQVIQ AARRLYSNP----------------SRPLPLPLVVEMNRNLLIGYSKFKDDPKIKHLKES VTGYNKRLAYLGIKDYQVETV----TKNRWRTLFLLTTRLVRLLVLLVLSLPGTVLFSPV LIACKVISRKKQKAALANSSVKIKAIDVLGSWKVLIALVAAPICYFIYSAIGTVLVFKYE --------LVRY--NSWNV-LVTFASWWALLVSTTYAAFVMGEVGMDIFKSIRPLILSL- -SPRSTD---LDELRKERQRLSAEITEVINELGPKVFP-KLDKHSLARL----------- -----------------EKEYEAEVED----------LRSRSRSRSQSRS---------- ---------------RSGSRSLSRASTQSGF--TE-NTMPNLSDVSIFPDALQLRDQSS- ----------------------LSPTSSSS------------------------------ -----S-------FVHLDSADKIAASGVN---------DHD--ASLLSKVR----NAVLK K--------RNEEARLE-----------GEKSD-------------------- >Saccharomycescerevisiae_YKR067W MSAP-------------------------------------------------------- -------AADHN-AAKPIPHVPQASRRYKNSYNGFVYNIHTWLYDVSVFLFNILFTIFFR EIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAGK---SRSRMPCFVT AESSFK-KRFISFFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHPEIIKGRSKNPQT TPVNFT-KRFSAKSLLGLPD-YLS----NAQIKEIPDDETIILSSPFRTSKS-------- -------------KVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAVA--ADPTMK---------------VAVVPCGLHYFHRNKFR SRAVLEYGEPIVVDGKYGEMYK---DSPRETVSKLLKKITNSLFSVTENAPDYDTLMVIQ AARRLYQPV----------------KVRLPLPAIVEINRRLLFGYSKFKDDPRIIHLKKL VYDYNRKLDSVGLKDHQVMQLKT-TKLEALRCFVTLIVRLIKFSVFAILSLPGSILFTPI FIICRVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALILAPILYVTYSILLIILARKQH Y----CRIWVPS----NNA-FIQFVYFYALLVFTTYSSLKTGEIGVDLFKSLRPLFVSIV -YPGKK----IEEIQTTRKNLSLELTAVCNDLGPLVFP-DYDKLATEIF----------- --------------SKRDGYDVSSDAE----------SSISRMSVQS------------- -------------RSRSSSIHSIGSLASNAL--SRVNSRGSLTDIPIFSDAKQGQWKSE- ----------------------GETSEDED------------------------------ -----EFDEKNPAIVQTAR--SSDLNKEN---------SRN--TNISSKIA----SLVRQ K--------REHEK---------------KE---------------------- >Saccharomycesparadoxus_Spar_11.357 MSTT-------------------------------------------------------- -------AADHN-ATKSVPHVPQTSRRYRNSYNGFVYNIHTWLYDVSVFLFNILFTIFFR EIKIRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAGK---SRSRMPCFVT AESSFK-KRFISLFGHAMGGIPVPRIQDNLKPVDESLEIYAPDLKNHPEIIKGRSKNPHT TPVNFT-KRFSVKSLLGLPN-YLS----NAQIKEIPDDETIILSSPFRTSKS-------- -------------KAVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAVA--ADPNMR---------------VAVVPCGLHYFHRNKFR SRAVLEYGEPIIVDGKYGEMYK---DSPRETVSKLLKKITNSLFSVTENAPDYDTLMVIQ AARRLYQPV----------------KARLPLPAIVEINRRLLFGYSKFKDDPRIIHLKQL VYDYNRKLDLVGLKDHQVMQLKT-TKLEGLRCFVVLIIRLIKLSVFAALSLPGSILFTPI FIICRIYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALILAPVLYVTYSILLIILARKQH Y----CRIWLPS----TNP-LIQFVYFYALLVFTTYSSLKTGEIGVDLFKSLRPLFVSIV -YPGKK----IEEIQTTRKNLSLELTAVCNDLGPLVFP-DYDKLATEIF----------- --------------SKRDGYDVSSDTE----------SSISRMSAQS------------- -------------RSRSSSIHSIGSQASNAL--SRVNSRGSLTDIPIFSDARQGQWKSE- ----------------------GETSEDED------------------------------ -----EFDEKISGTVETAQ--NSDSNKEN---------SRD--TDISSKIA----SLVRQ K--------REHEK---------------KE---------------------- >Saccharomyceskudriavzevii_Skud_11.303 MSTD-------------------------------------------------------- -------PADHA-TAKSVAHVPQASRRYRNSYNGFVYNIHTWLYDLAVFLFNILFTIFFR EIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMAQTRLLKTSAGE---SRSRMPCFIT AESSFK-KRFISLFGHAMGGIPVPRIQDNLKSVDENLEIYAPDLKNHPEIIKGRSKNPQS TPVNFT-KRFSAKSLLGLPN-YLS----NAQIKEIPDNETIILSSPFKTSNA-------- -------------KVAGLLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAVA--ADPGMK---------------VAVVPCGLHYFHRNKFR SRAVLEYGEPIIVDCKYGEMYK---ESPRETVSKLLKKITTALFSVTENAPDYDTLMVIQ AARRLYQPL----------------KVKLPLPAIVEINRRLLFGYSKFKDDPIIIHLKKL VYDYNKKLDLVGLKDHQVMQLKT-TKLEALRCLVILVTRLIKLSVFAMLSLPGYILFTPI FIICRVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALILAPVLYVTYSILLIVLARKQH Y----LRIWVPS----SNP-FVQFVYFYALLVFTTYSSLKTGEIGVDLFKSLRPLFVSIV -YPGKK----IEEIQSTRKNLSLELTAVCNDLGPLVFP-DYDKLATEIF----------- --------------SKKEGYDVSSDTE----------SSISRMSGQS------------- -------------RSRSSSIHSIGSQASNAL--SRVNSRGSLTDIPIFSDTRQGQWKSE- ----------------------GETSEDED------------------------------ -----EFDGK---TVETPQ--NPDLNKEN---------TRD--TDISSKIA----SLVRQ K--------REHEK---------------KE---------------------- >Saccharomycesmikatae_Smik_11.329 MSTA-------------------------------------------------------- -------AAHHN-AAKSVAHVPQASRRYRNSYNGFVYNIHTWLYDLSVFLFNILFTIFFR EIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMVQTRLLKTSAGE---SRSRMPCFIT AESSFK-KRFISLFGHALGGIPVPRPQDNLKSVDENLEIYAPDLKNHPEIIKGRSRNPQT TPVNFT-KRFSAKSLLGLPN-YLS----NAQIKEIPDDETIILSSSFKTSKS-------- -------------KVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGTVA--ADPNMK---------------VAVVPCGLHYFHRNKFR SRAVLEYGEPIVVDGKYGEMYK---DSPRETVSKLLKKITNSLFSVTENAPDYDTLMVIQ AARRLYQPL----------------KVKLPLPAIVEINRRLLFGYSKFKDDPRIIHLKEL VYDYNKKLDSVGLKDHQVMQLKT-TKLEALRCFVILVTRLVKLIVFAILSLPGSILFTPI FIICHVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALILAPILYVTYSVLLIFLAEKQH Y----YRVWVPS----NNL-FLQFVYFYSILVFTTYSSLKTGEIGVDLFKSLRPLFVSIV -YPGKK----IEEIQATRKNLSLELTAVCNDLGPLVFP-DYEKLATEIF----------- --------------SKREDYDVSSDTE----------SSISRMGAQP------------- -------------RSRSSSIHSIGSQASNAL--SRVNSRGSLTDIPIFSDARQGHWKSE- ----------------------GETSEEED------------------------------ -----EFDEKNKATAEIAQ--RSDLNKEN---------GRD--MDISSKIA----SLVRQ K--------REHEK---------------KE---------------------- >Saccharomycesarboricola_EJS42831 MSAA-------------------------------------------------------- -------AAEHN-AAKSAAHVPQASRRYRNSYNGFVYDIHTWLYDMCVFLFNILFTIFFR EIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAGE---TRSRMPCFIT AESSFK-KRFISFFGHAMGGIPVPRSQDNLVPVDDNLEIYAPDLKNHPEIIKGRSKNPQT TPVNFT-KRFSARSLLGLPN-YLS----NAQIKEIPDDETIILSSPFRTSKS-------- -------------KVVELLTNGTGFKYSEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAVA--ADPNMK---------------VAVVPCGLHYFHRNKFR SRAVLEYGEPIIVDARYGQMYK---DSPRETVSKLLKKVTNSLFSVTENAPDYDTLMVIQ AARRLYQPL----------------KVKLPLPAIVEINRRLLFGYSKFKDDPRIIHLKKL VYDYNKKLDLVGLKDHQVMQVKT-TKLEALRCLVILVTRLVRLSVFVLLSLPGSILFTPI FIICRVYSKKKAEEGLKKSLVKLKGTDLLATWKLIVALILAPILYVTYSILLIILAKKQH Y----YRIWVPS----NNL-FFQFFYFYALLVFTTYSSLKTGEIGVDLFKSLRPLFVSIV -YPDKK----IEEIQKTRKNLSLELTAICNDLGPLVFP-DYDKLATEIF----------- --------------SKRDVSDVSSDTE----------PSINRMSGQS------------- -------------RSRSSSIHSIGSQASNAL--SRVNSRGSLTDIPIFSDARQGQWKSE- ----------------------GETSEEED------------------------------ -----EFEEK---KLEFTQ--RFDLNKEN---------AHD--TDISSRIA----SLVRQ K--------REHEK---------------EE---------------------- >Saccharomycesbayanus_Sbay_11.302 MS---------------------------------------------------------- -------AAAAA-AAKSVAHVPQASRRYKNSYTGFVYDIHTFFYDLSVFLFNILFTIFFR EVKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRQLRTSAGE---SRSRMPCFIT AESSFK-KRFISLFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHPEIIKGRSRNPQT APVNFT-KRFTAKSLLGLPN-YLS----NAQIKEIPDDETIILSAPFKTSKA-------- -------------KAVELLNNGTTFKYAEKIDNTETFQNVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAVA--ADPSMK---------------VAVVPCGLHYFHRNKFR SRAVLEYGEPIIVDSKYGQMYK---DSPRETVSKLLKKITNSLFSVTENAPDYDTLMVIQ AARRLYQPL----------------KVKLPLPAIVEINRRLLYGYSKFKDDPRIIHLKIL VHDYNRKLDLVGLKDHQVMQVKT-TKWEALRCLVTLITRLIQLSVFAILSLPGSILFTPI FILCHVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALVLAPILYVTYSILLMILAKKQH Y----FSIWVPS-----NP-FLQFVYFYALLVFTTYSSLKTGEIGMDLFKSLRPLFVSIV -YPGKK----IKEIQNTRKNLSLELTAICNDLGPLVFP-DYDKLATEIF----------- --------------SKRDGYEVSSDVD----------SSTSHLSGQT------------- -------------RSRSSSVHSIGSQFFNAL--SRVNSRGSLTDIPIFSDPRQGQWKSE- ----------------------GETSEDED------------------------------ -----LTEEK---TVENTQ--NLDLNKEN---------GRD--TDISSRIA----SLVRQ K--------REHEK---------------KE---------------------- >Candidaglabrata_CAGL0K08162g M----------------------------------------------------------- -----------------PAHVPEVGHKYINDYNGYTYNIHTFLYDLIVFLFNAVITTFFR EIKVRGGYNVPPRGVPTILVCAPHANQFIDPTLVMITTRQLGYIRGK---LRSRQACFVT AASSLK-MKFVGLFGNAMGSIPVPRIQDNLKDMDSNLIIYAPDFENNPTMLKGKCLDGSN P--GFT-TKFTVKSLIGLPN-YLS----NANIAEIPDDSTIVLSAPFKNDKN-------- ------------GKVAELLTQGTTFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAAA--ADPKME---------------VAVVPVGLHYFHRNKFR SRAVIEYGEPIMVNGDMGKEYK---QQPRETVSRLLKKVSDALFTLTENAPDYETLMTIQ AARRLFQTN----------------NSRIPLPAVVEIQRRLLVGYKKFQSDPRIMHLQNS VKEYNNKLYSMGLKDHQVMSLKT-KPYETLRCAVTLLQRIFRVTLFFFLSLPGSIMFLPI FVGSHFYSKKKQREGLKKSSVKIEGKDLIATWKLIVALLMAPSLYITYTIILMVLHQRRS K--YVWWVWVPT----ENK-VIQFIYFYMLLVLVAYSSLKTGEIGFDLFKSLRPLMISLV -YPQDY----IHELQTRRKELSNEVTEICNELGPQVFP-DYEKFASSYL----------- --------------IKKDKKDESKPEK---DY-----LSQNSTGLSG------------- -------------RSRSSSIYSMISNVSNSL--SRVNSRGSLTDVPIFSDSRQGEWTNI- -----------------------TSDDEQS------------------------------ -----N-------------------SKEE---------TPT--NKLSSKIT----DLMRS K--------REKEK---------------VD---------------------- >Naumovozymacastellii_XP_003675893 M----------------------------------------------------------- -------------PPKSNAHVPEVSRTYKNNFNGLVYNIHTWTYDCIIFLFNIIFTIFFR EIKVRGGYNVPPAGTPTILVCAPHANQFIDPTLVMVTTRKLGMYGAT-SVSRSRQACFVT AASSLN-MKLVGFFGRRMGGIPVARAQDYLKPVDDNLEIYAPDLENNPKLIKGRCKDSKS P--EFT-KRFTAKSLLGLPN-YLS----NAQIAQIQDDETIILSSPFKISDP-------- -------------RVRKLLNNGTTFKYANKVDNSKVFQSVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAAA--ADANIK---------------VHVVPVGLHYFHRDKFR SRAVLEYGEPIVVDGTMGKEYA---QAPRETVSKLLSRITDALFSVTENAPDYDTLMTIQ AARRLYQPS----------------EKRLSLPVVVEINRRLLVGYSKFKSDERVIHLKKM VQEYNEKLYSMGLKDHQVRELESHTVQNTIRTLVTLVTRVSRLLLFFMLALPGSILFTPI FIGSSIYSKKKAREGLKKSLVKIKGTDLLATWKLILALVMAPISYVTYSLILISLHSRKN G--WVQWIWVPS----ENV-FIQFPYFYMQLVLTTYGSLKTGEIGMDLFKSLRPLVVTLM -YPGKK----IREIQSIREQLSEEITSVCNELGPSVFK-DFDQFAINNE----------- --------------IESERGRGRYEKEKTPDYLKIQRDPSRSRSRGA------------- -------------RSRSSSISSFTSRISNAI--SRVNSRGSLSDIPILSEARYSSNNVI- ----------------------NDSDSSCS------------------------------ -----S-------------------SDEE---------NIK--AGSTSKIS----SLMRA RWE------KSHDK---------------EE---------------------- >Kazachstaniaafricana_XP_003958593 MERSNSE----------------------------------------------------- --DVKKSTSASS-APSAKAHIPNHTTEYVNPFNGESWTIFTFLYDLSIFIFNIIFTIFFR EIKVRGTYNVPSNGTPTILVCAPHANQFIDPTLVMTTTRKLM-------NGRSRQSCFVT AESSFK-YKVVGFFSKCLGSIPVPRIQDNLKPVDANIQIFAPDRVNEPTLIKGCCKDGSS P--KFT-KLFTEKSLIGLPK-YQG----NAQISKILDDETIILTSPFKS----------- ----------------EAISTPTNFNYAPRVDNTKTFQYVFDHLHTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAAA--ADPSMN---------------VSVVPVGLHYFHRQKFR SRAVVEYGEPIIVNHEMGLAYA---NHPRETVSKLLDKIQDALFSVTVNAPDYDTLMTIQ AVRRLYEPA----------------THKFSLPMILEINRRLLVGYSTFKDEPRIIHLKNA VSKYNDTLYSMNLKDHQVEQLKT-SSLETIRCIIVLLTRLATLYLFFILSLPGSVLFTPI FITAHVYSKKKAKEGLKKSLVKIKGVDLLATWKLIVALVLAPLLYTTYSLALVYLFNRNP SNFIVRWIWIPNFIPRMGN-IPLFVYFYSLLVLTTYSSLKTGEVGMDLFKSLRPLFVSLF -YQSDK----IKQLQKMRQNLSVEITNVCNEYGPSVFP-DFDKMNFANP----------- ----------------------ENKFK----------FYNNDERAKS------------- -------------RSRSSSFTSIFSGVSNAL--SRVNSRGSLSDVPILGYSRL-DYTSD- -----------------------TIADDSS------------------------------ -----D-------------------EEDI---IDISIRNKD--KAESSKIT----SIVRE RWN------REHEK---------------ND---------------------- >Vanderwaltozymapolyspora_XP_001643508 MS---------------------------------------------------------- -------DEKPS-NKGPSAHIPSADVKYSNPYNGLVYNFYTWLYDFVLFILNILFMIFFR EVKVRGGHNIPPVGTPTIIVCAPHANQFIDPSLVMITARKVVYDNDKFDVNRSRQTCFVT AASGFK-KPIVGQFGIATGGIPVPRQQDNLSKVDNRIVLYCPDMN-KPTVIKGRVTDNSL ENPGFT-KRFTPKGLVGLPN-FLA----NAKIESIPDDYTIILSSPFKNIDAPI------ -----------QEKINYHIENGCTFKYAPKVDNSKVFQNVFNHLDTKGCVGIFPEGGSHD RPSLLPIKAGVAIMALGATA--ADPTLK---------------VSIVPCGLNYFHRQKFR SRAVIEYGEPIIVDGEMGKHYK---EDPRGAVSKLLKKVTDALYSVTENAPDYETLMTIQ AARRLYKPAS--------------NNKKIPLPVVCQVNRNLLLGYSKFKDDPRIINLKTA VQNYNERLYSLGIKDHQVLMLKT-GTAANIRTLVVLLNRIIKLGAFFTLALPGTILFTPV FVIAHYYSKKKQEEGLKKSVVKIKGIDLIATWKVMVALGFAPILYITYSLILVYTASTHR N--WLSWLWIPF----SNK-VMQFFYFYGLLVLTTYGSLKTGEVGMDLLKSLAPLFVTLL -YPEDT----ITDIQKLRNELSDEITDICNELGPEVIP-NFESYRNSRK----------- -----------------------SDED----------KSDSRSSSVT------------- -------------RSRSSSFSSL---FSNAL--SRVNSRGSLTDIPIFADGRNFNETED- ---------------------------SSS------------------------------ -----S-------------------DEEI---------DDD--NIFPSKIT----SIIRA R--------RQNEK---------------KEQ--------------------- >Zygosaccharomycesrouxii_ZYRO0B15708g MK---------------------------------------------------------- -------------EVKPGVHIPKLSQAYENPYNGEKYTLRTWLYDCVIAVLNVLFTIFFR EIKMRGEHKMPPQGVPTLLVCAPHANQFIDPSLVMVKARQMA------QGSRSRQVCYIM AEVSLK-KKILGLFGRLTGAIAVPRAQDNLKFVDQRIKIYAPDLDNEPRLIKGRVDGDGL ENPGFT--KFIPKSLIGLPN-FLG----NAQIESIVDDYTIVLKQPFKFQEN-------- ------------ATIRKLLERGTNFKYADKIDNSQTFQNVFDHLHTKGCVGIFPEGGSHD RPSMLPLKAGVAIMALVAAA--ADPTMK---------------VAVVPCGLHYFHREKFR SRAVIEFGDPIWVDGEMGKQYM---ESPRETVSKLLDRVTSSLQLVTENAPDWDTLMTIQ AARRLYKPV----------------MRRRALTAVVEVNRRLLLGYSAYKDDPRVIKLKES VTAYNGLLFLMGLKDHQVLELKT-KQGEQLRCLFTLIQRTIRLLVFFTLSLPGCILFTPI FIVCKVYAKKKAAEGLKKSVVKIKGVDLLATWKLLVALVLAPVLYVTYSIILTWLYLRGN T--LVVKMWVPS----THP-VLLYCYFCMLLVFTTYSSLKTGEIGVDLFKSLPPLFASLF -YPGSK----ITQLKEMRQGLSDEITDVCNELGPKVFP-KFERIIESQY----------- --------------EDKPRGRLSLPIS----------TKSQDEIPTL------------- -------------RSRSSSVASNLSTASNSL--SQINSRGSLTDMPIFSEGSHLDLNQD- ------------------------------------------------------------ --------------------------DEI---------NLS--SPEEDRIT----SLIRQ R--------RAHEK---------------ED---------------------- >Lachanceathermotolerans_KLTH0F17160g M----------------------------------------------------------- -----------------ASHVPK-SETFKNPYNGESYGLATWVYDLVVFVFNVCFTIFFR EIKIRGTHNMPCKGTPTILVCAPHANQFVDGALVMSQVRNLR-------GSRSRQTCLVT AESSYK-KRFISIFSRSTGGIPVPRAQDNLKPVDPALEIYVPDWA-EPTVLKCRVVGRNE SP-RLS-SRFTPKSLVGMPS-FLG----NAQIAEIPDDETLVLTKPFKDNS--------- -------------QVRDLLTKGTNFKYAPKIDNTSVFQNVFNHLHSNGCVGIFPEGGSHD RPSLLPIKAGVAIMALGAAA--ADPSSK---------------IHVVPCGLSYFHRNKFR SRAVLEFGQPIIVDGEMGKRYE---ADPRGQTSELLDKITQALYAVTVNAPDYETLMTIQ AARRLYQPAIAKTP---------DGNGHLPLPLVVEMNRRLLIGYSKYKDDPRIRHLKAM VLQYNSKLYALGLRDHQVPKLTS--KGGEWISLLTICTRVIRICFYLLLSLPGTILFMPV FVTCHYYAQKKAEDGLKKSLVKIKGTDLLATWKLLVALVLAPTLYVTYSLMLCYLVKHYP Q--LFESLWVIGTRTNGYT-SVNFVFFYALLVSATYASFKTGETGMDLFKSLPPLAVSLV -YTKRQ----LEDLKETRKQLSLEVTQVCNDLGPTVFP-DFGRFITTQK----------- ------------------------AAE----------RGEEDKDYVP------------- -------------RSRSSSVHSMESQMSNAL--SKVNSNVSLSDIPILAEGSNEQQDTI- ------------------------------------------------------------ -----E--------------------------------VEK--TEKPSLIG----NLVRQ R--------RQQEK---------------QD---------------------- >Kluyveromyceslactis_KLLA0F16104g M----------------------------------------------------------- -----------------AAKIPHVDSNYRNDYTGKKYTFRSWLYDVAVFIFDIVFTIFFR EIQVRGSYHVPTKNTPTILVCAPHANQFIDACLVMSQTRKIT-------GSRSKQTCFVT AEGSMKNNRFVGLFGSWTGAIPVPRVQDNLAPVASHFKLYIPNYDSDPTLVKLMSFEGPV ---RAT-SHFTPKSLIGLPG-YIG----SAQIETVVDDETIRLRKPFPDNN--------- -------------RVKNCVSKPTSFLYAEKIDNSKVFENVFNHLHTRGCVGIFPEGGSHD RPSLLPLKAGVAIMALGAAA--ADPTME---------------VHVVPCGLHYFHRNKFR SRATLEYTEPIIVTGEMGAAYL---KDPRGATSSLLKRIEEALYSVTMNADDYDTLMAVQ TARRLYQLSKRSTTGSTLPLSDNDSNHRIPLPLVVEMNRRLLVGYSKFKGEPRIQHLKKA IQDYNRMLFKMGLKDHQIMNLHP--KDEKWIVLVTLLIRCVQVYFIVLMSFPGVILFSPI FITCKYFSRKKALEGLKKSTVKIKGQDLIATWKIVVAISMAPTLYTIYSLIMVYITRKHP S--LYNWLIVPH-FIFKSK-LLYFIYCYVVLILATYVSFVTGEIGMDIVKSFPPLLVSLL -YPGHT----CEKLKKTRMKLSQDITEVCNDLGPMVFP-DLKEKRELRK----------- ------------EFFENDGSEIEDKDS----------DREADEEPNT------------- -------------RSRSSSVYSNDSSVSNAL--SKINSRGSLVDIPIFSDGPHCYQTED- ----------------------QDFPTSSV------------------------------ -----D--------------------------------IEP--LQPHSKIA----SLIRQ R--------REKEE-------------------------------------D- >Eremotheciumgossypii_NP_986967 M----------------------------------------------------------- -----------------SVRVPVVDPTYQNVYSGKHYAMATFLYDLAIFFFNIAFTIFFR KIHVRGTSNLPPQGRPAIVVCAPHANQFVDPTLVMTQVKKLP-------GQHSRRPCFVM AAASFK-KPLVGMLGRWTAGISVDRAADHLRVCEENMVLYCPDYDKDPLRYKVRPRDGAR AIRDVR-AVFTENGLLGLPG-NLG----SAQIAALEAPDAIRVQRPFGHSS--------- -------------AVRTLLERGTDFLYAPKLDNGTLFQDVFNHLHTKGLVGIFPEGGSHD RPSLLPIKAGVAIMALRAVA--ADPEME---------------ISIVPCGLYYFHRHMFR SRAVLEFGAPIIVDGAMGQKYL---QDPKTTVSELLDQVVNALYSVTVNTDDYDILMLVQ ATRRLYQAAW--------------GNKRVPLAAVVEMNRKLSIGYTKHKEHPRIKHLMLA IRDYDAQLYSLGLKDHQVDELRN-PNEKAVYIIFLFLTRLFHVLVFALLSLPGALLFSPI FITCHFYSQKKAREGLKRSLVKIKGDDLLATWKLVVAFCMTPALYAVYAALLTYLTFSHF H---------PL--IFANK-IGTFMCYYVLLLATTYASFVIGEIGMDVFKSLPPLFISLI -YPSQK----LQELREIRKNLSAEVY----AMGPAFFP-DLDRSDKSER----------- -----------------DSAVNSAPAQ----------LMEPALGPES------------- ---------PLLQRCATTTQLAFRNTVS-----ASGIIEAQANDVP----GKGRVVTED- -----------------------SCWSSSSYY---------------------------- --------------------------------------GHE--AASSFKTP--------- ---------AQDDR-----------------------------------K--- MAFFT CST26 YDR018c >Saccharomycescerevisiae_YBR042C_P38226.1 ------------------------------------------------------------ --------MLHQKIAHKVRKVVVPGISLLIFFQGCLILLFLQLTYKTLY---CRNDIRKQ IGLNKTKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFFLD---LKKKR-ILSHLKSN SVAICNHQIYTDWIFLWWLAYTS--NLGANVFIILKKSLASIPILGFGMRNYNFIFMSRK WAQDKITLSNSLAGLDSNARGAGSLAGKSPERITEE--GESIWNPEVI--------DPKQ IHWPYNLILFPEGTNLSADTRQKSAKYAAKI--GKK--PFKNVLLPHSTGLRYSLQKLKP SIE--SLYDITIGYSGVK-QEEYGELIYGLKSIFLEGKYPKLVDIHIRAFDV-------- --------KDI----------------PLEDEN------------EFSEWLYKIWSEKDA LMERYYSTG-SFVSDPETN-----------H---------SVTDSFKI-NRIEL---TEV ---------LILPTLTIIWLVYKLYCFIF------------- >Saccharomycesparadoxus_YBR042C ------------------------------------------------------------ --------MLHQKITHKVREVVVPGISLLIFFQGCLILLFLQLTYKTIY---CRNNVRKQ IGLNKTKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFYKD---LKKNR-ILSHLKSN SVTICNHQIYTDWIFLWWLAYTS--NLGANVFIILKKSLASIPILGFGMRNYNFIFMSRK WAQDKITLSNSLAGLDSNARGVGSLAGKSPERISEE--GESIWNPEVI--------DPEQ IHWPYNLILFPEGTNLSADTRQKSAKYAAKI--EKK--PFKNVLLPHSTGLRYSLQKLKP SIE--NLYDITIGYSGVK-QEEYGELIYGLKSIFLEGRYPKLVDIHIRAFDV-------- --------KDI----------------PLEDEH------------EFSEWLYKIWSEKDA LMERYYSTG-SFVSDLETN-----------H---------SVTDSFKI-NRIEL---TEV ---------LILPALTIIWLVYKLYCFFF------------- >Saccharomycesmikatae_YBR042C ------------------------------------------------------------ --------MLRQKITHKIRKVVVPGISLLVFFQGCLILLFLQITYKTLY---CKNRVKKQ IGLNKTKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFFKD---LKKDR-IFSHLKSN SVAICNHQIYTDWIFLWWLAYTS--DFGANVFIILKKSLASIPILGFGMRNYNFIFMSRK WAQDKITLSNSLAGLDSNARGIGSLAGKSPERINEE--GESIWNPEIT--------DPEQ IHWPYNLILFPEGTNLSADTRQKSAKYAAKV--GKK--AFKNILLPHSTGLRFSLQKLKP SIG--NLYDITIGYSGVK-QKEYGEQIYGLKSIFLEGKYPKLVDIHIRAFNV-------- --------KDI----------------PLEDEN------------EFSEWLYNIWSDKDA LMEKYYSTG-SFVSDVETN-----------H---------SVTDSFKI-NRIEL---IEV ---------LILPALTIIWLAYKIFSFFSY------------ >Saccharomyceskudriavzevii_YBR042C_EJT43172 ------------------------------------------------------------ --------MLRQKVIHKVRKFVVPGVSLLIFFQGCIILLFLQVTYKTIY---CRNAIRKQ AGLNRTKRLFIVLVSSILHVVAPSAVRITTENSSIPKGTFFKD---PRKNR-ILSHLKPN SVAICNHQIYTDWIFLWWLAYTS--NLAANVFIILKKSLASIPIIGFGMKNYHFIFMSRK WAQDKITLSNSLAGLDSNARGIGSLAGRSPERISEE--GESIWNPEII--------DPEQ THWPYNLILFPEGTNLSADTRQKSARYAAKI--GKK--PFKNVLLPHSTGLRFSLQKLKP SIG--VLYDVTIGYSGVK-QEEYGEEIYGLKSIFLEGRYPKLVDIHIRAFDV-------- --------RDI----------------PLDGEN------------EFSEWLYKTWSEKDA LLERYYSTG-SFVADVEAN-----------H---------SVTDSFKI-NRIEL---IEV ---------LILPTLTIIWLVYKLFSILFL------------ >Saccharomycesbayanus_YBR042C ------------------------------------------------------------ --------MLHNEIIRKIRKVVVPGLSLFVFFQGCIVLLFLQVTYKTIY---CRNAIRRQ SGLNETKRLFIVLASSILHVVAPSAVRITTENATIPKGTFFKD---LKKNR-ILSHLKPN SVAICNHQIYTDWIFLWWLAYTS--NLASNVFIILKKSLGSIPILGYGMRNYNFIFMSRK WAQDKITMSNSLAGIDSNARGIGSLAGKSPERISEE--GESIWNPEIV--------DPEQ IHWPYNLVLFPEGTNLSADTRQKSAKYAAKI--GKE--PFKNVLLPHTTGLRFSLQQLKP SIE--VLYDVTIGYSGLK-KEEYGEQAYGFKSIFLEGRYPKLVDIHIRAFNV-------- --------DDI----------------PLNDEN------------EFSKWLYKIWGEKDD LMEKFYSTG-SFITDVETN-----------H---------SVTDSFKI-NLTEL---TKL ---------LILPTLTMIWLVYKLFTLFF------------- >Vanderwaltozymapolyspora_YBR042C_XP_001645319 ------------------------------------------------------------ -------MMSAGRLIFKVRKVFFTALSIIVSIHGAFFLVTVQAILKFIY---KNNLTKLQ YGLNWTKRGFIILLVSVLNIVAPSSVRITTEDETIPRGTFIKD---LKKGR-IVSHLNKK SVMICNHQIYTDWVFLWWITYTS--NLAGNVYIMLKKSLEFIPILGYGMKNYRFIFLCRK WAVDRLVMNNQLGEIDADARGCGIVSGSSPKEINEE--GEESWDTSII-------GDRTN VKWPYSVILFPEGTNMSVATRQKSKEFAAKV--NRK--PYENVLLPRSTGLRFTLQKLST SID--VVYDVTIGYSGVK-KDEYGELIYRLPKIFLEGKMPKLIDIHMRALKI-------- --------EDI----------------PIDDED------------KFNNWLYDIWQEKDE LMEFYYKNG-TFKTNENCS---------------------EVTDFFTI-SNLEF---IGA ---------LSLPFMTLFLFLFTVLKIFN------------- >Zygosaccharomycesrouxii_YBR042C_ZYRO0A03586g MSL--------------------------------------------------------- -------SSGLNNGLRKCKIMVRVIIALVIFVQASLCITSMQVIVRVVY---HNNVAKRH HGIDFTKKAFISMLISTLHLIAPSAVRVTTDNNSIPKGTFYKD---LKNGR-IASHLKRK SVIVANHQIYTDWVFLWWLTSTA--DLAGKVYIILKKSLEYIPILGFGMRNYKFIFMCRK WEQDRLTLHNSLGVIDANSRGVGPISGRSPVREDAD--GEIFWDTTST--------NARQ ESWPYCLILFPEGTNLSPITRQRSFNYANKI--GKT--PFENVLLPHATGARHSLLKLRP SLD--VVYDITIGYSGVK-KGEYGEALYTLNNVVFKGESPKLVDMHIKAYHI-------- --------NEI----------------PIDDEQ------------QFSDWLYDLWAEKDR LMNVYYEKG-TFDLDPDPD-----------H---------TITGEFKI-SAYPF---FSC VV-------FINSLVCLPFLIWYLLR---------------- >Kazachstaniaafricana_YBR042C_XP_003956191 MAH--------------------------------------------------------- -------ASSNSWLIYNVKKVVVPLISILVFVEDIFVLLLCQLYITHFI---PKDTPRFQ NALDQTKKAFICILITIWHVVAPSKVRITTDNKTIPKGTFFID---LKKNK-FSSNIKPN SVTIANHQIYTDWVFLWWLAYTS--NLAGRVYIMLKKSLQSIPVLGYGMTNFKFIFMNRK WAADRVHLINSLRELDADARGTGSLTGSRPVSVDDN--GLINWNTTIQPSAEIKQSKKGT SCWPYNLILFPEGTNHTANTLSKSIIFAEKA--NRK--PLKNVLLPHSTGLRFCLRNLKP SLD--ILYDVTIAYSGIDKETKFAADAYGLGSIFLEGKYPSIVDIYIRAFEI-------- --------ENI----------------PIDDED------------QFVDWIYNVWKEKDE LLENYHKNGNSFGLDPELN-----------Y---------STMDGFSV-SNWEF---FLV ---------LAFPLASTLFLLKYILSLLF------------- >Naumovozymacastellii_YBR042C_XP_003678186 MSKH-------------------------------------------------------- ---QQNEEVHPGWIRYNVRKICFPFISIVIFVQDTMALLSAQAIGLFLL---SNDPLKVR HLLDATKRAFIVILMTILTIVAPSTIRITTDNKTITPSTFYRD---PKKGR-ICSQLRNN SITICNHQIYTDWILLWWLAYTS--TLAGKVYIMLKKSLEKIPVLGYGMKNFNFIFMDRK WASDKGTLDKQLTEIDARARGISKMQK--------------LHDKEIK--------KADA GVEPYNLILFPEGTVLSENTRNQSLAYAKKV--GRS--PFKCVLLPHTTGLRFSLQRLKP SLD--ILYDVTIGYSGVK-QDDYGENTYGLKSIFFEGKYPKLVDIYIRSYDI-------- --------KDI----------------PLDNEE------------EFIEWIYKVWQEKDL LLENYYKYG-CFHQDEKLS-----------T---------SVVNSFKI-NPLEF---YGA ---------LLLPICTLMFVLIIVYMSIF------------- >Lachanceathermotolerans_YBR042C_KLTH0C08096g ------------------------------------------------------------ --------MSVSFLAQRAVKLLVTLASIVIFIQGAFVIVTHQVLTKTFL---THDPIRMQ KHLDRSKKSFIILLITILTIVAPSGVRITTDNRSIPKNTMVKD---LRTGG-IISSMKQK SVLISNHQIYTDWVFLWWLAYTG--DLAGNVYIMLKNSLAKIPIMGYGMRNYNFIFMNRK WSKDRINLANHLGNLDHNARGVGRLAGKHPSLDIAS--GKEVWSDNGAAT-----KDHRQ IRWPYTLIIFPEGTNLSANTREKSRVFSEKA--NLP--IFNNLVLPRVTGLRFSLQELRN SCE--VVYDTTIGYSGVK-QNEYGQDIYQLSNIFLRGHSPDLVDIYIRAFNL-------- --------KDI----------------PLDDEE------------EFTKWLLDVWHEKDK LLDTFYAKG-SFDLDPNTH-----------Q---------VTTGTCKI-KSSEV---AQF ---------LILPLLSLAALVAKILRSFC------------- >Kluyveromyceslactis_YBR042C_KLLA0B06820g ------------------------------------------------------------ --------MLVSTILYRTYKVIVTFASMVIFIQGAISILVYQALINAFY---SKNLSTRQ KLMDLTKKRFILLLVTILSLVAPSHVRITTDNESIPKGTIYMD---HHKGR-LISKANSN AVVIANHQIYTDWVFLWWLAYVS--ERAGNVYIMLKKSLESIPLLGSGMTNYKFIFMNRK WEQDRINLSNKLHEIDLDARGVGIIAGNSPTTKTEE--GLNIWDEAKV--------EKKG EQWPYWLMLFPEGTNLSAGTRARNKAFAEKS--GLS--PFKHVLLPRTTGLKFCLQKLRN SCE--YVYDITIAYSGVR-AEDYGQDIYKLGNIFLKGKAPKLVDIYIRAIRL-------- --------DDI----------------PLEDDD------------EFHSWLFSVWNLKDK LLDNYYKTG-SFQLDPDLN-----------H---------AVTGPCRV-SILSL---VSI ---------LLFPVLTMLPIFYYIGKKATSLVSKDS------ >Eremotheciumgossypii_YBR042C_NP_983231 ------------------------------------------------------------ -------MITMSAVAQQAHRTVLAALVTFVFIQGCVSLVIFQFSMKCMY---RSNRIGLQ SQLDRSKKSFILLLVTIMTIVAPSYVRVTTDNASVAKGTFWRD---KGQGQ-LRSRLERN SVVISNHQIYTDWVFLWWLAYTS--GLAGRVYIMLKKSLAAIPVLGYGMKNYGFIFMNRR WNLDRVHLGNSLQRLDRDGRGLGPLAGHAPSRVTAE--GEEEYESQDG--------EASK QTWPYTLILFPEGTNMSSNTRERSNVYARKI--NVQ--PFENVLLPRSTGLRFALEKLAP SCD--CVYDVTIGYSGVK-KTTYAEQIYDLQSIFLRGQGPKLVDVHIRTFKL-------- --------SEI----------------PYKDEK------------AFEQWLYKVWGEKDK LLERYYQKG-SFDLDPDLT-----------H---------TVSGLCEI-DTAEV---FLV ---------MIVPMLILAAASFLFTKYAVQYFGKYSMAAAIY >Candidaglabrata_YBR042C_CAGL0I04620g ------------------------------------------------------------ -------MRKEQGQTGFARRTIVPVVSVVSFLSCCVVLLVIQVTAKLRF---SQNKTRLT HVYNYTKKQFIVLLTSILRIVAPCEIRVTTDNGSIPKGTFYQD---SSSGR-LRANLLER SITISNHQIYTDWVFLWWLAYAG--DKAGNVFIMLKKSLRKIPVLGYGMENFNFIFMNRK WAYDRVNMSNHLSAIEADSLGCGPISGNKPVKVNSD--GEEVWDMKSS--------AQRN IKWPYNLILFPEGTNLSAHTRKVNEAYAEKI--GRV--PYRHVLLPRATGLRFCLQKLRN SVD--VVYDTTIGYSGIL-STEYGQDAYSLKNIFFRGKYPKLVDIHVRSFKL-------- --------SDI----------------PIDDEI------------DFIEWLFKVWEEKDK MMEYFYEHG-TFENMTDNQ-----------E---------SVLVDCSI-KNYEF---FPV ---------FIIPFCFVLLTYWIVRSIF-------------- >Naumovozymacastellii_YBR042C_XP_003673979 MSL--------------------------------------------------------- -------SDVLSTSYSKFKHLTTTSLSIIVFIQGCISILITQFFIKLFY---YKNSEKLQ RGLNQTKRSFIILLLSIFSNVSPTSIRITTDDATMRRDSFQIN----RIGD-IIAQLDTN SIIFSNHQLYIDWVIIWWLAHLA--NLSGNFFILLKKSLEKIPLLGYGMKNYKFIFMNRK WAQDKSLLEQSLGAINTNAIENGK-------------------------------NKDLT NAWGYNILLFPEGTNLCTNGIRKNNAYCKKM--GLK--PMKNVLMPHTTGLRFMIQNLQP SLT--KIYDVTIGYSGVKGEHEFAEIKYSLKNIFLKGLGPSMIDIHIRSFNL-------- --------YEI----------------PYQDEE------------AFSKWLFTVWEDKNR LLDQYYIND-TFQGMDGKT-----------T---------LFCPAMDV-NPYDF---VTV ---------VFLPVAFGMVLTASLWAYFNKKLA--------- >Vanderwaltozymapolyspora_YBR042C_XP_001647122 MGA--------------------------------------------------------- --------------KYKSKQFVKALISTSILFNGVVLIASVQFIINNLFF--FVKNDTTK TALKRTKKAFIMMLITSLSIIAPATVRITTDNSSIKKGTVKFN---PVKGR-VVSNLKER SIVVSNHLIYTDWVYIWWLLYTS--NLSGSIFFLLKNSLQSLPLLSYIMNNYGFIPLTRN WTIDKLVVEEKLRLINNDAKIIIKDQEEVHTVQS----NQSSITVKSN--------VSPK SKWPYSVVLYPEGTNMSKRARQKSEEYSRKM--GRE--PFKNVLLPHTTGLRHSITLLQG TLD--TVYDITIAYSGVK-QDEYGEELYTLKNVFFKGIAPRLTDIYIRSYNI-------- --------SEI----------------PFTNEE------------KFTKWLFDVWEEKEK ILETYYETG-TFGVPREKV-----------D---------VIIERFDI-GIKQY---VES INTTNYKNNFTNNSNFIQILNQKI-----------------N >Candidaalbicans_YBR042C_XP_714343 ------------------------------------------------------------ ----------MNSRHSLPIVILRTAFITPLFILGCLSISLTQFLTLLIF---KNNPDVKQ AIINNTKNHFVILISYITTIVNPCKIEITIDETTVPNSDHFTV---DESNN-IHTMFQPN SVLISNHQIYTDWLYLWFLTYTS--KFGNSVFIILK-DLSKIPVLGYGMKNYNFLFLSRK WEKDKIVLTNQLLEIDANARGMGPANGVQLIGSSST------TNTEFT---KWPQGSNVN KIWPYELILFAEGTVPSDRTTKKSAEFIASR--GLP--PLKHVLLPRIRGLFLALKKLKS SVE--IVYDITTAYSGLT-EDQYGEIEYSLKRFYLKGYGPPKINYYIKGWKL-------- --------KDI----------------PLGEDVDDIDNILEQDLKKFEDWLLKIWYEKDK LMDNHYKLG-NWGELNHKT-------------------TRSIIGDFKLRNQFEI---FLP ---------FLATIATILFLRIAYILIRRIINV--------- >Candidaalbicans_YBR042C_XP_714065 ------------------------------------------------------------ ----------MNSRHSLPIVILRTAFITPLFILGCLSISLTQFLTLLIF---KNNPDVKQ AIINNTKNHFVILISYITTIVNPCKIEITIDETTVPNSDHFTV---DESNN-IHTMFQPN SVLISNHQIYTDWLYLWFLTYTS--KFGNSVFIILK-DLSKIPVLGYGMTNYNFYFLSRK WEKVKIVLTNQLLEIDANARGMGPANGVQLIGSSST------TNTEFT---KWPQGSNVN KIWPYELILFPEGTVPSDRTTKKSAEFIASR--GLP--PLKHVLLPRIRGLFLALKKLKN SVE--IVYEITTAYSGLT-EDQYGEIEYSLKRFYLKGYGPSKINYYIKGWKL-------- --------KDI----------------PLGEDVDDIDNISEQDLKKFEDWLLKIWYEKDK LMDNHYKLG-NWGESNHKT-------------------TRSIIGDFKLRNQFEI---FLP ---------FSATIATILFLRIAYILIRRIINV--------- >Debaryomyceshansenii_YBR042C_DEHA2F15664g ------------------------------------------------------------ ----------MIVRHAWPVVIGRTLVLGFFFVIGCISILGNQLIGTFVF---ANDAVQKQ AVINLTKKHFIALFGTITQWVSPCKISITYDPSTLPEGDSFKV---DPSGN-LSSILSPN SVLISNHQLYTDWLYLWFILYTA--KLGDSVYIMLK-DLSKIPVLGIGMKNYNFLFLSRK WEKDKIVLTNQLLTIDANARGLGPANGVTHVTSTNV------GSSELH---HWPEGHKAG QIWPYSVILYPEGTVTSARTRAKSNKFCEER--NMP--VLKHTLLPRVRGLFLTLRKLRN TVE--IVYDFTCGYSDLK-PGEYGEDIYTLKRHYLKGYGPKKISYHLRGWKL-------- --------SEI----------------PLGEETEDIDDVSSEDLIKFEEWLFKVWYEKDR MLDQFYKLG-SFVDPESEV-----------NYTAGKVAENTVVADFRINSIADI---VGS ---------FASLTIVLLILRIIWMTLSKILF---------- >Meyerozymaguilliermondii_YBR042C_EDK40103 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MKNFNFLFLSRK WEKDKVKLTNQLLEIDANARGLGPSCGETHISATNIRDGDAPETSSVF---HWPKGHRSS HMSPYQVILYPEGTVISPHTRERSAKFCQER--GLP--VLKHVLLPRIRGLFLALRKLRD TVE--VVYDVTCGYDGLR-PDQYGEDEFTLKQIYLRGNGPKKVSYYIKAWKI-------- --------KDI----------------PLGAETVDIDDVSPADFAKI------------- ------------------------------------------------------------ ------------------------------------------ >Millerozymafarinosa_YBR042C_PISO0I07774g M----------------------------------------------------------- ----------VYQELQQALVTVKGVLFLVFFAVGCVGIVSTQVIGLKLL---KAGSESRQ KLIDLTRTQFVALMTFVVSYMSPCKITITHDPDSVPENNYFRV---DSKGN-LVSSLTPN CVFIGNHQIYTDWLFIWFINQSS--RLGGHFHIIMK-NLSNIPVLGYGMKNFNFMFLSRK WESDKAVLSGQLATIDSNARGVGPSN------------------------------KDNK EHWPYSVLIYPEGTVVSENTKQRSAKFLAGK--GLP--PLKHVLFPRVRGLYLTLRGLRK SAT--VVYDVTCGYAGLK-PEDCGEDLFSLKNVFLRGNGPQASHYYIRAWKL-------- --------SDI----------------PLGDENTATDDFDEEQLAVFEKWLTKVWFEKDK LMASFYQHG-RFIDPNSST-----------SNTLDKVKRNTVTADFKVRQISDV---VGA ---------FGTLAFFVILINLIWVSASSFLA---------- >Millerozymafarinosa_YBR042C_PISO0J09601g M----------------------------------------------------------- ----------VYQEVQRALVTVKGVLFLVFFAVGCVGIVSTQAIGLKLL---KAGSESRQ KLIDLTRTQFVALMTFVVSFMSPCKITITHDPNSVPESNYFRV---DYKGN-LVSSLSPN CVFIGNHQIYTDWLFIWFINQSS--RLGGHFHIIMK-NLSEIPVLGYGMKNFNFMFLSRR WESDKAMLSGQLATIDSNARGVGPSN------------------------------KDNK EHWPYSVLIYPEGTVVSENTKQRSAKFLAGK--GLP--PLKHVLFPRVRGLYLTLRGLRK SAT--VVYDATCGYGGLK-PEDCGEDLFSLKNVFLRGNGPRASHYYIRAWKL-------- --------SDI----------------PLGDENTATDDFDEEHLAVFEKWLTQVWFEKDK LMASFYQHG-RFIDPNSNT-----------SNTLNKVNRNTVTADFKVRQISDV---VGA ---------FGTLAFFVILINLIWVSVSSFLA---------- >Saccharomycescerevisiae_YDR018C --------------------------MKHSQ----------------------------- ---KYRRYGIYEKTGNPFIKGLQRLLIACLFISGSLSIVVFQICLQVLL---PWSKIRFQ NGINQSKKAFIVLLCMILNMVAPSSLNVTFETSRPLKN--------SSNAK-PCFRFKDR AIIIANHQMYADWIYLWWLSFVS--NLGGNVYIILKKALQYIPLLGFGMRNFKFIFLSRN WQKDEKALTNSLVSMDLNARCKGPLTN---------------YKSCYS--------KTNE SIAAYNLIMFPEGTNLSLKTREKSEAFCQRA--HLDHVQLRHLLLPHSKGLKFAVEKLAP SLD--AIYDVTIGYSPAL-RTEYVGTKFTLKKIFLMGVYPEKVDFYIREFRV-------- --------NEI----------------PLQDDE------------VFFNWLLGVWKEKDQ LLEDYYNTG-QFKSNAKND-----------NQSI---VVTTQTTGFQHETLTPR--ILSY ------YGFFAFLILVFVMKKNH------------------- >Saccharomycesparadoxus_YDR018C --------------------------MKDYQ----------------------------- ---EYHPHNIYGKTSNSFIRALKRVFIICLFLSGSLSIVVFQICVQLLL---PWSKIRLQ NGMNQSKKAFIVLLCMILNMVAPSSLNVTFETSQSSKN--------SSNTK-SCFRFKDR AIIIANHQMYADWIYLWLLSFTS--NLGGNVFIILKKALKYVPLLGFGMRNFKFIFLSRN WQKDEETLTSSLISMDLNARCKGPLTN---------------YKTCYS--------KTNE SIAAYNLIMFPEGTNLSPKTREKSDAYRQRA--HLNHVQLRHLLLPHSKGLKFAVEKLAL SLD--AIYDVTIGYSPAL-KTEYVGTKFTLKKIFLMGVYPERVDFHIREFKV-------- --------DEI----------------PLQDDE------------VFFNWLLNVWKEKDE LLENYYNTG-QFKSKGETE-----------NRST---VVMKQTIGFQHETLAPR--FLSY ------YGFFAFLIFLFVMKKILELALR-------------- >Saccharomycesmikatae_YDR018C MFT---------------SMFHHLGKMRKHQ----------------------------- ---ETHKRDIYQKTSNVFIKGLQRLFIICLFLLGSLSIVIFQVCLQLLL---PWSKIKLQ NGMNQSKKAFIILLCLILNMVAPSSLNVTFETSHPLKI--------SSNTM-SHFKFKDR AIIIANHQMYADWIYLWWLSLVS--NLGGNVFIILKKTLKYVPLLGFGMQNFKFIFLSRN WQKDEETLTNSLVSMDMNARCMGPLTD---------------YKNCYS--------NTNE SVAAYNLIMFPEGTNLSLKTREKSEAYRQRA--HLSHVQLRHLLLPHSKGLKFALEKLTP SLE--AIYDVTIGYSPAL-KTEYVGTKFTLKKIFLMGIYPEKVDFHIREFKV-------- --------NEI----------------PLQDDE------------AFFNWLLDVWKEKDE LLENYYNTG-YFKGNDKNK-----------NPSA---VITKQTKGFHHDSLAPW--ILSY ------YCFFAFLILLFTMKKLLELTLS-------------- >Saccharomyceskudriavzevii_YDR018C_Skud_4.270 -------------------MPHSLGPMKQQQ----------------------------- ---GCFHHDIYRKTNNVFIQALQRVFIICFFLMGSFSIVIFQVCLQLIL---PWSKIRLH NGMNQSKKAFIVLLCLILNMVAPSSLNVTFEASKSSKS--------SSGTN-SSFKFKDR AVIMANHQMYADWIYLWWLSSIS--NLGGNVFIILKKALKYVPLLGFGMQNFKFIFLSRN WRKDETTLTNNLVSMDLNARCKGPLTN---------------YKTCYS--------KTNE SVAAYNLIMFPEGTNLSPKTKKKSEAYCQRA--GLQDVQLRHLLLPHSKGLKFALEKLAL SLD--AVYDVTIGYSPAL-RTEYVGTKFTLKKIFLMGVYPERIDFHIREFKV-------- --------DEI----------------PLQDDE------------VFFNWLLGVWKEKDQ LLENYYNTG-QFRSDDENR-----------NRSV---VITKQTDGFQHDASAPR--ILSY ------YGILAFLVLLFTMKKISEFTLP-------------- >Saccharomycesbayanus_YDR018C MYPRAVNKPWGRVPDVPTTMLHGSGEMKQTQTQTQ------------------------- ---TQQYHDIYHKTNNAVIKALQRVFIICFFLLGSLSIVIFQVCLQLLL---PWSKIRLQ NGMNQSKKAFIILLCLIMNMVAPSSLNVTFETSRSSKS--------SPSAN-SRFKFKDR AIIMANHQMYADWIYLWWLSFVS--NLGGNVFIILKKTLKYVPILGFGMQNFKFIFLNRN WQRDEKTLTNSLVSMDLNARCKGPLSN---------------YKTCYS--------KTNA SIAAYNLIMFPEGTNISPRTRERSEAYRQRA--RLHHVQLRHLLLPHAKGLKFALEKLAP SLD--AVYDVTIGYSPVL-KTEYAGTKFTLKKILLMGIYPERIDFHIREFEI-------- --------SEI----------------PLQDDE------------VFFNWLLDVWKDKDE LLENYYNSG-QFKSLDESK-----------NPSA---VVVKQTDGFQHDALAPR--ILSY ------YGMLAFLVFLFAMKKLSELTVS-------------- >Komagataellapastoris_YBR042C_XP_002490189 M----------------------------------------------------------- ---------VLEKQRLNPFKIFRLGFIILFFFSGCLSIVITQIIVKILF---CFNPLQQQ RLLNFTKRNFIILLTFVTSLVSPTKIIITHDESI-PNGTFTHHRTFTGNDI-VRAALSPQ AIVVANHQIYTDWLFMWWFAFIS--DVSDNVYIIMKKSLSKIPVLGYGMTNYRFIFLSRK WEDDKSIMIRQLKEITY------------------------FYGNKSA--------KAFD DLKKHWLIIFPEGTNMSDNRRKISNEYIQKN--GLE--PLNHVLSPRAKGLYVSVEKLSP TTK--YIYDLTIAYSGHT-PDEYAQDIYTLSQIFIHGKGPHSVNIHIRALDL-------- --------HQIGGVNFDPEIVNSSNEIQESNLV------------PFQNWLYKVWCEKDA LLDQFFSTK-SFGAQYE-----------------------SIETELKLFSKWEL---LSI ---------FTPTWLLLLGFYFVVKLLIMVF----------- >Ogataeaparapolymorpha_YBR042C_ESW97278 MSS--------------------------------------------------------- -------VQQQQSRKPTIYQVVRLVFAILTFATGCLSIVFSQLLVNVTL---GGDEGLRT RWIGFTKRNFVILITFITSLTCPTDLELSFDSDTVSCREVLAN---AERSL---LKLNTS AILIANHQLYTDWVFLWFVSYLN--ECAENFYIIMKKSLERIPILGYGMKNYDFIFLNRK WDLDRSYMIQRFAHLSS------------------------------------------- -VKKHWLLIFPEGTNLSPNTKPRSDDFMTRQ--HLD-FKLDHVLLPRVKGLYLACKHMHK KTN--LILDFTMAYSDHL-ATEYAQDSFTLRSIYLLGKGPKSLSMFVRAIDI-------- --------SSIDGCTFDE---NANEEEEEEDMR------------KFEVWLNKLWVQKDK MMDNYYKTG-HLVEGVK-----------------------STKIPLKLRNRFEI---LNV ---------YVIPIVFFVLTWLACRLITTLLR---------- >Yarrowialipolytica_YBR042C_YALI0F02937g MATAEAVKASG------VAGESSSASQRVAKSAPS-------TDP--------VIPVDIP LAVPTTNKELPPPRHSKPSQVLRGVIAVFYFLCACLSIVLTQWIGYPLK---YQSKMAWV VWVEYTKQQFIVVMLCLVQALTSTEMRVSGDETM--KGVFSVD----GNGY-LSSRFEER AIVIANHQLYTDWIYLWWFALTS--GFGGCIYILLKKSLRSIPILGSGMANYNFIFLSRK WADDEQNMKEHFQGLN-------------------------------------------K LQAPVWLTMFPEGTNTSHNGTNNSNKFAAKI--GVK--PMKHVLLPRTTGLRFAIENLAQ TVD--YLYDCTLAYEGVG-RGEYGQDFYTLGNVFLRGQGPVYVKAHWTKFVI-------- --------KEI----------------PYKDEK------------KFEKWLYDLWYDKDQ MMDNFIETG-KFFPDNEES-----------E---------KIAK-LQLAHPLQG---LQV ---------FVIPAAAALILRLGWKYWQTI------------ >Geotrichumcandidum_YBR042C_GECA13s01935g MAI-------------------ETPPLSERASFP---------VP--------------- ---LGKRNNNLVLPPSAFVRWLKLPLCVTFLLSSAVSINITQLVGQPLY---YVSRNWYE AWTEYTKQLFGIVVIFITQYWTPLKVSITGNSSV--AGLFSIN---AKTGL-LETHFDGR AIVISNHQLYSDWIFLWWVAFTA--RYHGNIFIMLKDSLKHIPIFGWGMRNYRFLFLSRS WVKDEKTLTEGLSRINRDS----------------------------------------- -DWPAWLILFPEGTTISRNGVAKSRAFAEKQTPALR--SPSHLLLPRSRGLRFSIEQLHE TVE--YIYDSTIYYSDIP-EGVFGEDHFTLRRMYLQGVYPSSIAMYWRRYRI-------- --------ADI----------------PWQDEA------------KFEKWIYDRWYEKDA LLQHYHKTG-QFTDPENEA-----------GNDD----IPTLEAPVRLSNTVGD--VFKI ---------FVVPITTGLLVRLGYNALTRIASNA-------F >Schizosaccharomycespombe_YBR042C_NP_595192 MTC--------------------------------------------------------- ------------------RIAIRKYSFILCLAVGSVTIYTSEVIGTPLY---FVNKELYN KYIAFTKSFAGILFTALVQLFSPTPVTLTYDPEL--RNLFYLD----RNGC-LETIAAER NIVIANHQLYSDWMYVWWLSYTA--KQHGHVYIMLKNSLKWLPVIGWGMQLFRFIFLSRK WDKDYETMSRHFKFIRN------------------------------------------- VRDSVSLILFPEGTNLVESTYQRSRVYADKI--GVK--MPKHLMLPRVRGLFYSISQLRD SMT--YLYDYTFYFSDPS-PKKYAADAFSLPKLFFEGVPIKRLHIHVRRFPI-------- --------SEI----------------PTEED-------------QFTDWLYQRWYEKDK LIDTLLETG-NFPGPKKLH------------------------TTVRLKHRLEILSLFSV ---------LFTCIVAGLFLKLFISH---------------- >NeurosporacrassaOR74A_YBR042C_XP_958192 MG-----------------------DLRQNASYPDIASGDASTNPNPDQAGLLVQPNDDA LKTVQNAHPSGKEKHNRLIQILRGVSLAIFFTACSVGIVATQFLGAPLY---WINRDLYY TYMALTKESFGLTITTMTQWWGPTTIRISGDGSV--AGQIKKT----PDGR-VEFNFPER MVMIANHQIYTDWLYLWWVGYANAPRMHGYLYIILKESLKYLPIVGQGMMFYGFIFMARK MSVDQQRLAYRLGKLKTKHT-----------------------------------HDGKQ YLNPMWLLLFPEGTNCTQNGRDKSKKWADKM--GIK--DTEHVLLPRSTGMYFCLKELKG TVD--YVYDCTVAYEGVP-RGMYGDQFFTLSSTYLRGQPPKSVNFYWRRFAV-------- --------DDI----------------PLENQE------------EFDVWLRERWYEKDA LMEQYLTTG-RFPPSPATK-----------EGGH----EGHLETEVRARHPLEF---LKI ---------FSVLGWVGVMATTAVRTWGRVAQWT-------S >Aspergillusfumigatus_YBR042C_Phy0041VWN_ASPFC MDS---------------------PELRQRKPAPGLKGDNMVEKP--------------- ---QGSKDAEPRLKHGIPMQLLRSLLLATWFNCCCIIIFTTQLIGSPLY---FINKDYYY SYMALTKQSFGLVITALTEWGCPTYVRVSGDESV--RGQIHLC----KDGR-LKTQFPER LVLIANHQVYTDWIYLWWIAYTN--QMHGRIFIILKESLKYIPIIGQGMTFYGFIFMARK WLSDKPRLQHRLEKLKTQTSGS---------------------------------ESESP QYDPMWLLIFPEGTNLSPNTKRRSDEYGRKQ--GLP--PLKHELLPRSTGLLFCLQQLKG TVD--WVYDCSVAYEGPP-KGSYPDKYFTLRSTYLQGRPPTSVNMYWRRFAM-------- --------SDI----------------PLDDQK------------EFDSWLRARWTEKDE LLDEFFETG-RFPTALAGSIDAGNVSDVQIEAAS----KGFVETHVRLHHWTEL---GRI ---------FMVLTGMAVLCRL------------PKVFGLWD >Cryptococcusneoformans_YBR042C_XP_568878 MAQKPL----------------YTIPINDRPP----------HGP--------------- --------------------WTSKILFPVIFTLAQLSINSAQFLLVPLLLVPFVGKRLFS RAIGWTKDGYGRLLIAITVLFGPTQFAITTDTPPPHGQTLVER---DMNGQVVKINLPDR LVIMANHQAYLDWIYIWILACYA--GHSAGLIILLKASLKNIPVIGWGMRFFNFIFLRRS WVADRDNLTLALRQLGQEAQS-----------------GQENSETATL--------LPLR KRSPLWLLIFPEGTIISDEERVKSIKYAKKE--GVD--DFATLLHPRSTGLLFCLRTLLP QIPDLNLLDITIGYPGVP-FGNYPQNWYGLFSVFLKSVPPPTVYLHLHVYSHLGEPECKI PSLVPRRSSNVSGLSTDSGLA------NAEEAR------------AFELWLRNLWTAKER RMEQFYESQ-RFGGPCDIV-------------------------PIQQIKWYHW---ISA IGG----GGLGTVVLLAFCIWFAVCR---------------- MAFFT SLC1 >Saccharomycescerevisiae_YDL052C ------------------------------------------MSVIGRFLYYLRSVLVVL ALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGE-ENL--AK-- ------------------------KPYIMIANHQSTLDIFMLGRIFPPGCTVTAKKSLKY VPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKK----NKRALWVFPEGTRSYTSEL TMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVS--PKYGVFNRGCMIVRILKPISTENL- TKDKIGEFAEKVRDQMVDTLKE-IGYSPAIND-TTLP----------------------P QAIEYA--ALQHDKKVN-KKIKNEPVPSVSISN------DVNTHNEG------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SSVKKMH-------------------------------------------- --------------------- >Saccharomycesparadoxus_YDL052C_Spar_4.229 ------------------------------------------MSVIGRFLYYLRSVLVVL ALAGCGLYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGE-ENL--VK-- ------------------------KPYIMIANHQSTLDIFMLGRIFPPGCTVTAKKSLKY VPFLGWFMALSGTYFLDRSKRQEAIETLNKGLESVKK----NKRALWVFPEGTRSYTSEL TMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVS--PKYGVFNRGCMIVKILKPISTENL- EKEKIGEFAEKVRDQMVKTLKE-IGYSPAVND-TTLP----------------------P QAIEYA--ALQHDEKAN-KKIKDDPVPSVSISN------DVNTHNEG------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SSVKKIH-------------------------------------------- --------------------- >Saccharomycesmikatae_YDL052C_Smik4.187 ------------------------------------------MSVIARFLYYLRSVLVVL ALASGGLYGVIVSIICTLIGKQHLAQWITARCFYHVMKLVLGLEVTVIGE-ENL--AK-- ------------------------KPYIMVANHQSTLDIFMLGRIFPPGCTVTAKKSLKY VPFLGWFMALSGTYFLDRTKRQEAIDTLNKGLENVKK----NKRALWVFPEGTRSYTSEL TMAPFKKGAFHLAQQGKIPIVPVVVSNTSTLMS--PKYGVLNRGRMIVKILKPISTENL- TKDKIGEFAEQVRDQMVTTLKE-IGYSPAIND-TTLP----------------------P QAIEYA--ALQHDRKVN-KS-KNEHATSVGISN------DVSTNHEE------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SSIKKMN-------------------------------------------- --------------------- >Saccharomyceskudriavzevii_YDL052C_Skud4.203 ------------------------------------------MSLLAKFLYYLRSVLVVL ALAAGGLYGVIASIICTLIGKQHLAQWITARCFYRVMKLVLGLDVQVVGE-ENL--VK-- ------------------------KPYIMVANHQSTLDIFMLGRIFPPGCTVTAKKSLKY VPFLGWFMALSGTYFLDRSKRQESIETLNKGLEDVKK----NKRALWVFPEGTRSYTSDL TMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVS--PKYGVFNRGRMIVRILKPISTENL- TKDKIGEFAEKVREQMLDTLQE-IGYSPAIND-TTLP----------------------P QAVEYA--ARQHDQKKN-KI-KNEPLHSVSAND------DVSVHHEG------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SSVKKMH-------------------------------------------- --------------------- >Saccharomycesarboricola_YDL052C_EJS44387 ------------------------------------------MSVPAKFLYCLRSVLVIL ALSSCGLYGVIASIFCTLIGKRYLAQWTTARCFYHVMKLLLGLDVKVVGE-ENL--TN-- ------------------------KPFVIIANHQSTLDIFMLGRIFPPGCTVTAKKSLKW VPFLGWFMALSGTYFLDRSKRKESIETLNRGMENVRK----NKRVLWVFPEGTRSYTSEL TMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVS--PKYGVFNRGCMIVKILKPISTENL- TKDKVGEFAEKVRDQMIDTLKE-IGYSPAHND-TNLP----------------------P QAVEYA--AL-HDKTKN-KM-NNEPVSSVGVSD------GVSIHHEG------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SSMKKMH-------------------------------------------- --------------------- >Saccharomycesbayanus_YDL052C_Sbay_4.198 ------------------------------------------MSVLAKILYYLRTVLAVL VLSGCGLYGVVASIFCTLIGKQHLSQWTTARSFYYAMKLVLGLDVKVIGE-ENM--PK-- ------------------------KPFIMIANHQSTLDIFMLGRIFPPGCTVTAKKSMKY LPFLGWFMTLSGTYFLDRSSRQQAVETLNRGLENVKK----NKRALWVFPEGTRSYTTEL TMLPFKKGAFHLAQQGHIPIVPVVVSNTSTLTN--PKYGVFNRGCMIVKILEPFSTENL- TKDKVGEFSEQVRTRMIDTLKE-IGYSPAIND-TTLP----------------------P EALKYA--TLQQEKRKN-AI-KNGAVSSVGANE------DVSVHHEG------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SSAKRMH-------------------------------------------- --------------------- >Kazachstaniaafricana_YDL052C_XP_003958479 --------------------------------------------MANNFLYYFRTFLAVV VLMVSALYGTLASIVCLIIGKQHLAQWTTARFYYYASKYIMGIDVKVINE-HNI--TN-- ------------------------LPCIAVSNHQSALDILVLGRMFPKGCTVSAKKSLRY VPILGWFMALSGTLFLDRGNREKSVKTLNNSLRKIKD----NKRALWIFPEGTRSYTTDL ETLPFKKGAFHLAQQGNIPIVPVVVSNTSTIMF--SKWNVFNRGTLIIKVLDPIPTSDL- KKEDIGAFTEKVRDLISKELKE-VGYSIPIVD-TNLP----------------------P NLVEKN--GRIVKKALP----AKDIVEEVPASS------SIGITAEK------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Naumovozymacastellii_YDL052C_XP_003673188 ------------------------------------------MGGFNTILYYNRCVLGIV VLLLCAVYGVLASIVCTLIGKQQYSQYLTARCYSNAMKYIMGIDVKVIGE-ENL--KN-- ------------------------LPYIVVSNHQSAMDILMLGRMFPPGCTITAKKSLKY VPFLGWFMALSGTLFLDRTNREKSVGTLNTGLAKVKE----NKRALWIFPEGTRSYSINL EMLPFKKGAFHLAQQGELPIVPVVVSNTSSIFS--PKYNVFNRGTIIVKVLKPISTEGL- KKEDVGKFSEQVRETMVAELKE-VGYSDAFNE-TNLP----------------------P SVVELN--GKIISAVK-----KDDPADVVTKEN------DDDKDKTT------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------NATKEF--------------------------------------------- --------------------- >Vanderwaltozymapolyspora_YDL052C_XP_001643441 ---------------------------------------------MHSALYYLRVVYSVV ILVIAALYGVVASMLCTILNKSEYSQYVCARFYYSVMKYFFGIDVKVINE-HYL--RN-- ------------------------LPFIAVSNHQSTLDILMLGKCFPPGCTITAKKSLSY IPVFGWFMIASGTYFIERTNREKSVKTLNRGLQDVKD----KKRGLWIFPEGTRSYTTDL TMLPFKKGAFHLAQQGGIPILPIVVSNTSTLMS--PKWGVFNRGCITVKVLEPIPTENL- KPEDVSEFAETVREKMIKELKENVGYSDYVND-TSIP----------------------P GIEDKK--TN-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Candidaglabrata_YDL052C_CAGL0I04070g ------------------------------------------MGFFSIALYYLRTVSWVL ILMVAAAYGTVASVFLTLIGKQHLAQWATARFYYYAMSMLMGIDVKIINE-DVL--KG-- ------------------------KPFIAVSNHQSTLDILFLGRIFPQGCTVTAKKSLKY VPFLGWFMALSGTYFLDRSNREKSVSTLNRGLQNIRE----KKRALWIFPEGTRSYSTTP KILPFKKGAFHLAQQGQIPIVPVVISNTSTIMC--SKYNVFNRGCITCKVLDPIPTKDL- KKEEVGELAEKVRNMMEKEIMD-LGYSKAIND-TNLP----------------------P EAIEYM--QKNNKKPSS-VESTTEYGSIKKDEATVMVSSGSNSHLEQLS----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Zygosaccharomycesrouxii_YDL052C_ZYRO0B07326g --------------------------------------------MLRKALYYFRFTLATA VLCGCSLYGVVASIVLTLVGKQHLAQWATARCFYYASILFLGIDVKVENE-HYL--EN-- ------------------------KPYIIVSNHQSTLDILMLGRVFPQGCTVTSKKSLKY TPFLGWFMTLSGTLFLERANRQKSVETLNRSLDVLKK----EKRALWIFPEGTRSYTTNL NILPFKKGAFHLARQGKLPIVPVVVSNTSTLMN--HKWKVFNKGCIVARVMKPISVDDL- TTEDVGKFSEDLREKMLTELQD-LAYSQATVD-THIP----------------------P EAKAYK--RVENATALS-SENSSERVSTLTKEI------DN------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Lachanceathermotolerans_YDL052C_KLTH0D13772g ------------------------------------------MGFWAKFVYYSRSVLGVT LLSTCALYGVVASIVLSCIGKRHLAQWTTARSFYYVMGTFLGIEVEVINE-ENL--KK-- ------------------------LPAILVANHQSALDILMLGRIFPPGCTVTAKSSLKW VPFLGWFMMLSGSLFLERGNREKSVRTLNNALDVMRT----KKRAVWIFPEGTRSHSTKL GLLPFKKGAFHLAQQGKIPIVPIVVSNTSTLMN--SKYKVFNRGVITVKVLDPIPTDDL- KKEDVTAFTKRVEELMLKEVEN-LGYSDAMLD-TNLP----------------------P EVRSSV--TQVLTSSTI----TDSEEQDVSTKD------SVEEAVEALEAEDEDEGE--- --------------------------------------------PER------------- ---------------------------------------------NETAV---------- ------------------------------------------------------------ ------------------------------------------------------------ ------Q------------------------------NEDVTA----------------- -------------------QAQEPEIQEPEIQEPETQESEAQEPEAQ------------- DSKAD-AKDSKAKAKHSKA----------------------------------------- -------------------KK >Kluyveromyceslactis_YDL052C_KLLA0E01233g ------------------------------------------MGFFSKIVFWGKSVIAVT LLSSCALYGVLASIVFSLIGKKHLAQWSTARCFYGVMGFIMGIKINLING-ERL--ND-- ------------------------LPAIFISNHQSELDILMLGRTFPPGCTVTAKKQIKW VPLLGWFMSLSGTLFLDRSSREKAIKVLNDSLANLKK----DKRALWIFPEGTRSYSTKL ELSAFKKGAFHLAQQGKIQIIPVVVSNTSSIYH--PRSGVFNRGTITVKVLEPISTENL- KKEDVGDLCNRVHKLMNDELKN-IGYSEAIVD-TVLP----------------------A DVIAYN--SARRFEDQH-RLTADDYEEEIVDLD------RSSIHSNG------------- ------------------------------------------------------------ -----------------------------------------------TVV---------- ------------------------------------------------------------ ------------------------------------------------------------ ------T------------------------------NPEPTE----------------- -------------------RS--------------------------------------- ---------SLLKEVI-------------------------------------------- --------------------- >Eremotheciumgossypii_YDL052C_NP_986139 ------------------------------------------MGVFGKVIFYAKSAVAVL LVSTCAVYGMVASVVLSVVGKRHLAQWTTARAFYF-LGGCLGINIKLINA-ERL--GQ-- ------------------------LPAVIVSNHQSELDILLLGRAFPPGCTVTAKESLRW VPILGWFMALSGTVFLDRSNRSKSLKSLNASLERLKR----NRQAAWIFPEGTRSYTTEM QLLPFKKGAFHLAQQAQIPVIPVVMCNTSTVFN--PRLGIFNRGTITAKVLEPIDTANM- TKDDVDKLVSDVQAKMQAEFEA-LGYAPAIVD-TSLP----------------------E EALRPE---------------FVDCKEDITEVT--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------RLLK----------------------------------------------- --------------------- >Vanderwaltozymapolyspora_YDL052C_XP_001643328 ------------------------------------------MSVGSSIVYNVKTGICIF ALGFCAILGMISSILLSLIGYRHISQFVTTKTYYTIVSALLGVEVKVINE-KNL--DN-- ------------------------QPCIYVCNHQSSLDAIILGKLFPPGCTITAKKSLKY VPILGWFLSLSGTLLIDRKNTAEGIATLNKSLEELVK----HKRSLWIFAEGTRSYSESL DMLPFKKGAFHLALQGKIPIVPIVVSNTSNLQN--GRYHIFNRGTVVVKVLDPIPTTKL- TKDKVGEFSEMVHNKMLNELRKNVGYSQLEEG-STLP----------------------P KFDAKK--IENKVGLDD-IEIIESTSQQRS------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Komagataellapastoris_YDL052C_XP_002489498 ---------------------------------------------MSSVVYYVKGFFALL ALTSCAVYGVIASTVLSLLGKRNLSQWSTARVFYATFSTLFNIKIEVDRP-EIL--EK-- ------------------------LPAILVSNHQSELDVFILGKVFPKRCSMTSKKQLKW VPFLGQFMTLSGVFFLDRANKSTAISTLDTALQKLKN----EKGALYIFPEGTRSYALEP KLLPFKKGAFHMAVQGGIPVIPLVASNTSSLYS--PKTKTFKSGVIKIKVLDPIETKDL- TKDDVADLAQEVYDKMKTAVDL-LGYSPTNDQ-LEAE----------------------T DVDTET--ESETGNTYT------DTEEDITVPG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ETT------------------ ------------------------------------------------------------ ---------QLLDK---------------------------------------------- --------------------- >Ogataeaparapolymorpha_YDL052C_ESW97514 --------------------------------------MSFLQKIGKHFKFYTKGFVALC TLMVSASYGVLCSVFLSLIGKRNLAQWSTARFYYYLFSTVMRITIEIEGE-EKL--SG-- ------------------------LPAILISNHQSELDVFMLGRIFPKRCVVTAKKQLQL VPFLGWFMTLSGTFFLDRSDREKAIRVLNKALDDLKA----TSGGLFMFPEGTRSYSSRP TLLPFKKGAFHLAVQAQIPIIPLVVSNTSNIYS--LKERNFNTGTIKVKVLEPISTEGL- TKDDVNKLVEATYAKMEEEIRK-VGMSVVAGD-VSGE----------------------S EALLSQ--EVQ------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Geotrichumcandidum_YDL052C_GECA01s06258g MG---------------------------------------FFGVIPPLQFYVRLLVYVL LIVISALYGVVASVILTLIGKQGLSQWTVARVFYFFAGHILGIKVVIKNP-EAL--TT-- ------------------------RPAVFVANHQSELDILMLGATFPQYCSVTGKKILKY YPFLGWFMTLSGSVYIDRVNRENALKAFSSAIEQVKS----RNQSVFIFPEGTRSYSTTP KLLPFKKGAFHFAQQAQIPIVPWVVSNYSKVFS--FKTRTFVPGTIVIEVLEPVSTVGK- TAADVSELASVVESRMTEVVAK-LGYGDGKSY-ADKTK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Neurosporacrassa_YDL052C_XP956681 M----------ASLLYYPVYFLEGCVALTIG-------FYMLSLILPRAAFVARSLASYL SLLLCAGFGVITSIAFSLLGHGQSAQWAVGRSFKYVMALTTGVRFKIDDP-KNILGKT-- ------------------------RPAVFIGNHQTELDVLMLGCMFPKYCSVTAKSSLRK TPFLGWFMSLSGSIFIDRASKTDARAAMAGAANQIQK----KQQSVYMFPEGTRSYSKEP ELLPFKKGAFHLAVQAQVPIVPVVVANYSHVLN--VKDFVFNAGVIPMKVLDPIDTTGL- TTADVDELCKNTRDLMLKELIA-LTAKARGQSVSDIP-----------------VANKYP SVAKAS-----------------GTDMQVAA----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Aspergillusfumigatus_YDL052C_XP755194 -----------MSLLSYIASGISSFVVVTLS-------LFALGQKVPRAAFFARCLAAYG SLLLCACYGVIASILLRLVGYGRVSQWATARSFKWVMRYTTGVQFDIIQGAEHL--ST-- ------------------------RPAVFIGNHQSELDVLMLGHIFPPYCSVTAKKSLKH IPFLGWFMALSRTVFIDRANRETAMKAFDGAAEEMRK----YRQSVFIFPEGTRSYSEKP ELLPFKKGAFHLAVKAGVPIVPIVAENYSHILS--PRNMRFNPGVIKLKVLPPISTEGL- TAADVDRLTKTAQESMLKALLE-LSDQDRDEIDSD------------------------- -VKKAT-----------------STAVEI------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Candidaalbicans_YDL052C_XP_720080 --------------------------------------MSAVSSFFTKLKFYLKSGLYGT LVAGCAIYGVLASIILRIVNKAEYAQYAVAKACYYVVSLFLGLKINIKNE-KYL--QN-- ------------------------LPAIVVANHQSALDIYVLGKVFQPGYTVTSKKSLKY VPFLGWFMALSGTFFLDRSKSASAKKVLDGALTGLKN----QGKALFIFPEGTRSATEDL TMLPFKKGAFHLARQAGIPIIPVVVSNTSTIFN--SKRKIFNTGEINIEVLPPVSTSDWE THEDVTNACNNIRDDMIKTLKK-LGNSKIPGS-KPREDF-------------------YP SESEDT----------------SETDVEIINEQ--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------T------------------ ------------------------------------------------------------ ---------PLKATAVSD------------------------------------------ --------------------- >Millerozymafarinosa_YDL052C_PISO0L01397g -----------------------------------------MGSLISKIRFYFKCFLYGA VTTGAGLYGVIASIILKLLGKNEYSQYTVARAFYYPFSWLSGVKITIKNE-ERL--HQ-- ------------------------RPAVVISNHQSALDLLMLARIFQVGYTVTAKKALMY VPVLGWFMLASGTFFLDRSKSDKARKVLEGALKSLKR----NHGSLFMFPEGTRSATKEL DMLPFKKGAFHLAKQAGIPVLPCVVSNTSNIFD--SKNKIFNSGEIIIEVLEPMSTEGLE TNEDVTKFTEQVRSKMLERLQA-LGYSKTPES-STPV----------------------P SASADTVPSETISSAPAKLDTSSKKTRKSVSSE------DIT------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------EAT------------------ ------------------------------------------------------------ ---------PLVA----------------------------------------------- --------------------- >Millerozymafarinosa_YDL052C_PISO0K01396g -----------------------------------------MGSLISKIRFYFKCFLYGA VTTGAGLYGVIASIILKLLGKNEYSQYTVARAFYYPFSWLSGVKITIKNE-ERL--HQ-- ------------------------RPAVVISNHQSALDLLMLARIFQVGYTVTAKKALMY VPVLGWFMLASGTFFLDRSKSDKARKVLEGALKSLKR----NHGSLFMFPEGTRSATKEL DMLPFKKGAFHLAKQAGIPVLPCVVSNTSNIFD--SKNKIFNSGEIIIEVLEPMSTEGLE TNEDVTKFTEQVRSKMLERLQA-LGYSKTPES-STPV----------------------P SASADTVPSETISSAPAKLDTSSKKTRKSVSSE------DIT------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------EAT------------------ ------------------------------------------------------------ ---------PLVA----------------------------------------------- --------------------- >Debaryomyceshansenii_YDL052C_DEHA2G01496g MDCGINDVCINQLLFFHDVCFCSTIYLQSVD-----RQLGQMSSIINSIKFYVKSTVFGV LISGCALYGVVASILLRLVGKKDYAQYTVARVFYHTFSKILGIKITIKNE-HFL--HD-- ------------------------VPGIIVSNHQSALDILMLGKVFHPGYTVTAKKALQY FPFLGWFMLASGTFFLDRARGEKARKVLDNALKSLKA----EKRALFMFPEGTRSATKEL EMLPFKKGAFHLAQQAGIPIIPVVVSNTSNIFN--AKDRIFNSGEIFIEVLKPMPTDDLE TNSDISAFSVQVRDEMLEALQR-VGYSVPSGT-SSEQ----------------------P SANGQT--EEEITD----IDTDTDPEQSEFSEE--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------T------------------ ------------------------------------------------------------ ---------PLIGK---------------------------------------------- --------------------- >Meyerozymaguilliermondii_YDL052C_EDK40560 -----------------------------------------MGSAFSSLKFYFKSVAFGV LISVCALYGVFASIFLRIIGKPQYAQYTVARAFYYSFSTVLGVKINIKNA-HYL--NE-- ------------------------KPAIVISNHQSALDILVLGKTFTPGMTVTAKRALKF FPFLGWFMLASGTFFLDRTRGEKARKVLDGALASLKR----DNRALFIFPEGTRSGTTKL DLLPFKKGAFHLAKQAQIPIVPFVVSNTSGIFH--ASTRTFNRGEITIEVLPPMSTSHLE TNEQLNDFALEVHDKMKTTLQN-LGYSKVPGF-KKE------------------------ ----ET--AVEALD----TDDTDEVAIERVPEH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------T------------------ ------------------------------------------------------------ ---------PLLSKD--------------------------------------------- --------------------- >Geotrichumcandidum_YDL052C_GECA04s00340g M-------------------------IQSV--------LLFTQKVTKYIKFYAKVSGIFA AFVGSAAYGTIAPILLSLVGKRLLTQYTVARLFYFLVHKITHLTIEIEDPHGYI--TD-- -----------AAAP--------PTSSIILANHQNEIDVLLIGRLFPKYTTVTAKKILKY IPILGWFMTLSGSVFLDRSNRERSIQTLSAAVNTIQH----TRQNLFLFPEGTRSYTPTP ALLPLKKGAFHLAVEGQFPIIPVVVSNNAKIWRTATQDKVIPGGLIRVRVLEPIPTVGL- TAADVNALVARVETLMRAEVEK-LGYSEVHGL-DNTNKI-----------------EEHR DIDEAT------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------PLIED---------------------------------------------- --------------------- >Yarrowialipolytica_YDL052C_YALI0E18964g ------------------------------------------MSVASKLVFYVRAAIAVV IFAACATYGVLASTILTAIGKQGLAQWTVARAFYYSVRIFLGISIKLRSR-QVT--GT-A GLDASKIQVANTTKPIDDITKHLPRPCILISNHQNEMDILVLGRIFPQYCSVTAKKALKW YPLLGQFMALSGTIFLDRKDRTKSVQTLGGAVKTIQSGNGGKGQSVFMFPEGTRSYSKDV GIMPFKKGCFHLAVQSGAPIVPVVVQNTSRMFS--FGRGKLDAGEILVDVLSPIETKGL- DASNVDALMATTYKAMCETADQ-IGYAGQKTQ---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Schizosaccharomycespombe_YDL052C_NP_594605 MG------------------FIKSTLLATVTVFVGLCGINRFFTLPKCIRYHFRYFACHT FLAISSAYGVIASVVARLCGYPVMGQYLTAKAYYGLASTILDFRFKIENE-EIL--RK-- ---------------------H--KSAVLVVNHQSELDILAIGRTFGPNYSVIAKKSLRY VPILGWFMILSDVVFIDRSRRSDAIQLFAKAARRMRK----ENISIWVFAEGTRSYSLKP CLLPLKKGAFHLAVQAQVPIIPIAIQTYGHLFH--PPTKVFNKGEALIKVLDPIPTEGK- TAEDVNDLLHETETAMNNALVEIDDYGKVKKQ---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >Cryptococcusneoformans_YDL052C_XP_567944 MG---------ISWLLKPVALVSTVALST---------LGVLSRRYQRARFYFNLTIYVS TLGLMSVWGVVVSILATAAGQRLNINYYVARSLYGLSGPLLGIKFEVEGE-EHL--EGLM TARDGQ---------------H--QGAVLLSNHQSFLDILYIGRIFPKQAAIMAKKELKW TPLLGQFMSLSGAVFVNRKNRHDAVKALAIAGEDMKK----KGVSLWIFPEGTRSSSPEP TLLPFKKGAFHLAVQAQIPIVPIVCENYHRLFD--GRTR-FESGVLKIRVLPPIPTTGL- TVDDVTSLAESTRESMLHALRE-ISEPGPSSS-TPIP----------------------T SAEVPL--APPISRNTTQPPAGDSIQLDISESGALR---QRGVHSSGVSSE-WSEG---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------KFEAQ-------------------------SEETTED---------------- -------------------EMDED------------------------------------ --------VVLLKKPKENVA---------------------------------------- --------------------- >Cryptococcusneoformans_YDL052C_XP_570434 ---------------------------------------------MWKVIYYLNLALYTI LLISTSFLAVLIAIVCSLTGRRLNTNYFVARTFYCIAGTILGWKFQVEGE-QYL--WELS GEHGGG----KANEK------G--RSMVMVGNHQSFVDILYLGRIFPKHAAIMAKKSIQW IPGLGWFMMMSGTVFINRSNNKSAIASLQHAGEEMKR----KRISLWIFPEGTRHNTPEP ELLNFKKGAFYLAVQAGVPIVPVVCENYNHLFN--GKSH-FRRGTLRIKVLPPISTTGL- TAADVPGLIERTRNAMLETLQE-ISTPSQSTSQAGSPDPLLGRSGREREDYYTSGSPAPP QSVPST--AEIGTEEEAEAAVEDAIGREEADNG------ERHVPVVGKNNK-EDETMSSP RRLVIAMVSDFFFPVIGGVEGHIYSLSVELMRRGHKVIVITHSHPDRLGIHYLEPSLKVY YLPYLPIASSASLPNFLLFLPYFRHIILTENIQLVHGHGALSSLAHEAVIHAPLLGVKAV FTDHSLFGFGDAVGVLTNKLLGAALRCVDEVICVSNTGRENTVLRAQLDPSIVSVIPNAL EAEHFKPDPFRADPDWITIVVISRLVHRKGIDLLISSAPQICALFPKVRFIVGGDGPKMV ELEQMREKYELQGRVELLGRVNPGDVRDVLTKGQIYLSNSLTEAFGISIIEAASAGLFVV ATKVGGVPEILPQDMIEFCRADEDDVIRALTHAIHTIQSSRHSPWSAHIRVRDMYSWSHV SSRAEIVYLRAMSRPHREIGERMRRYLELGPVFGVVMCCILAVEHYFFWLLEWWNPRDKL RQVISFPGVERFEDRGKNNKK MAFFT DGA1 >Saccharomycescerevisiae_YOR245C MS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GTFNDIRRR---------------------KKEEGSPTAGITE------ -------------------RHENKSLSSI----DKREQTLKPQLESCCPLATPFERR--- --LQTLAVAWHTSSFVLFSIFTLFAIST-PALWV-LAIPYMIY-FFFD-RSPATGEVVNR YSLRFRSLPIWKWYCDYFPISLIKTVNLKPTFTLSKNKRVNE---------KNYKIR--- -----------------------------------------------LWPTKYSI----- ----------------------------NLKSNSTIDYRN-------------------- -------QECTGPTYLFGYHPHGIGALGAFGAFAT--------------------EGCNY SKIFPGI-PISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLSK--------NQSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------SSTNGTQLILNKRKGFIKLAIQTG------NINLVPVFAFGEVDCYN VLSTKKD------------SVLGKMQLWFKENFGFTIPIFYARGLFNYDFGLLPFRAPIN VVVGRPIYVEK------KITNP-------------------------------------- -------------------PDDVVNHFHDLYIAELKRLYYENREK----YGVPDA----- ----ELKIVG--- >Saccharomycesparadoxus_YOR245C_Spar_15.451 MS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------ETVNGIRRR---------------------KSGEGSPTAGIAE------ -------------------RHENKPLSNI----DKRDQTFKPQLESCCPLATPFERR--- --LQTLAVAWHTSSFVLFSIFALFAMST-PALWV-VVIPYMIY-FFFD-RSPATGDVVNR YSLRFRSLPIWRWYCDYFPISLIKTDDLQPTFTLSKNKTINE---------KIYKVR--- -----------------------------------------------LWPTKYSI----- ----------------------------NLKSNSTVDYRD-------------------- -------QECTGPTYLFGYHPHGIGALGAFGAFGT--------------------EGCNY SRIFPGI-PISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLSK--------NQSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------SSTNGTQLILNKRKGFIKLAIQTG------NINLVPVFAFGEVDCYN VLSTKKD------------STLGKMQLWFKENFGFTIPIFYARGLFNYDFGLLPFRAPIN VVVGRPIYVEK------RITNP-------------------------------------- -------------------PDDVVNHFHDLYIAELKRLYYENREK----YGVPDA----- ----ELKIVG--- >Saccharomycesmikatae_YOR245C_Smik_15.429 MS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GITKDIRRR---------------------KNEEGSYTSGIAE------ -------------------GIENRPLSNI----DKKDQTLKPQLELCCPLATPFERR--- --LQTLAVAWHTSSFVLFSIFALFAIST-PALWV-FVIPYMIY-FFFD-RSPATGDVVNR YSLQFRSLPIWRWYCDYFPISLIKTVNLKPTFTLSKSKTFDE---------HVYKIR--- -----------------------------------------------LWPTKYVI----- ----------------------------NLKSNYTVDYRD-------------------- -------QECTGPTYLFGYHPHGIGALGAFGAFAT--------------------EGCNY SKLFPGI-PISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLGK--------NQSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------SSTNGEQLILNKRKGFIKLAIQTG------NINLVPVFAFGEVDCYN VLSTKKD------------STLGKMQLWFKENFGFTIPIFYARGLFNYDFGLLPFRAPIN VVVGRPIYVEK------QILDP-------------------------------------- -------------------PDDVVNHFHDLYIAELKKLYYDNKEK----YGASDA----- ----ELEIVG--- >Saccharomyceskudriavzevii_YOR245C_Skud15.412 MS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------DRTSIIRRR---------------------KNEEGSPTAGIAE------ -------------------QHENKPLASI----DKKDQTSKPQLESCCPLATPFERR--- --LQTLAVAWHTSSFVLFSIFALFAVST-PALWV-FVIPYMIY-FFYD-RSPATGDVVNR YSLQFRSLPVWRWYCDYFPITLIKTVGLKPTFTLSKNKISNE---------RVYKIR--- -----------------------------------------------LWPTKYSI----- ----------------------------NLKNNSTIDYRG-------------------- -------QECTGPTYLFGYHPHGIGALGAFGAFAT--------------------EGCNY SKTFPGI-PISLMTLVTQFHIPLYRDYLLALGISSVSRKNALKTLSK--------NQSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------GSTNGPQLILNKRKGFIKLAIQTG------NINLVPVFAFGEVNCYN VVSAKKD------------SILSKMQLWFKENFGFTIPIFYARGLFNYDFGLLPFRAPIN VVVGRPIYVEK------QIEDP-------------------------------------- -------------------PDDVVNYFHDLYTEELERLYYENREK----YGVSDA----- ----ELTIVG--- >Saccharomycesbayanus_YOR245C_Sbay_8.295 MS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------ETTNTLRRR---------------------TNEEWSATAGIAE------ -------------------QHENQPSVST----DKKDQSPKPQLEFCCPLATPFERR--- --LQTLAVAWHTSSFVVFSIFALFAIST-PALWF-FVIPYMIY-FFFD-RSPATGDVVNR YSLQFRSLSVWRWYCDYFPITLIKTADLKPTFTLSKNKNNND---------KVFKIR--- -----------------------------------------------LWPTKYSI----- ----------------------------NLKSYSTIDYRD-------------------- -------QECTGPKYLFGYHPHGIGALGAFGAFAT--------------------EGCNY SKIFPGI-PISLMTLVTQFHIPFYRDYLLALGISSVSRKNALRTLSK--------NQSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------SSTNGTQLILNKRKGFIKLAIQTG------NTNLVPVFAFGEVNCYN VLNTEED------------STLGKMQLWFKENFGFTIPIFYARGLFNYDFGLLPFRAPIN VVVGRPIYVEK------QIVNP-------------------------------------- -------------------PDDVVNHFHDLYIKELKRLYYENRNK----YGVTDA----- ----EFKIVG--- >Saccharomycesarboricola__YOR245C_EJS41575 MT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------DTISNIRIR---------------------TNRKGGHMAGIAE------ -------------------QQENKSLLSN----DKRDQTPKPQLESCCPLATPFERR--- --LQTLAVAWHTSSFVLFSIFALFAIST-PTLWV-FVIPYMTY-FFFD-RSPATGDVVNR YSLQFRSLPIWRWYCDYFPITLIKTVEMKPTFTLSKNKSNNE---------KVYKIR--- -----------------------------------------------LWPTKYSI----- ----------------------------NVKSNSTIDYRD-------------------- -------QECTGPTYLFGYHPHGVGALGAFGAFAT--------------------EGCNY SKTFPGI-PISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLSK--------NQSIC IVVGGARESLV------------------------------------------------- ------------------------------------------------------------ -------------SSTNDTQLILNKRKGFIKLAIQTG------NINLVPVFAFGEVNSYN VLNTDKD------------SALGKMQLWFKENFGFTIPIFYARGVFNYDFGLLPFRTPIN VVVGRPIYVEK------QIANP-------------------------------------- -------------------PDDVVNHFHDLYIEELERLYYENREK----YGVSDA----- ----EFKIVG--- >Kazachstaniaafricana_YOR245C_XP_003954956 MK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------SDTAQNTLTKR---------------------KLSVPPPPSSSSS------ ---------------------STSSTTNI----SINDENDEPTLDHCTPVTTPLKRR--- --LQTLIVACHLTSFVLFSIFVLFIISA-PIFWG-MLIPYLIY-FTFD-RSPANGNVVKR YSLWFRSLPIWKYYISYFPITLAKTCDLKPTFNKDTGKAE-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GPRYIFGYHPHGIAALGAFGAFAT--------------------EALGW NEKFPGI-PVCLMTLVTQFIIPFYRDYLLALGITSVSRKNSLKVLSN--------NYSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------SSSDSTELILNKRRGFVKLALETG------NVSLVPVFAFGEDKCYK ILRTPDN------------SVLRKVQFWVKENFGFTIPLFYARGLFNYDFGLLPFRHPIH VVTGKPIYVEE------KIEHP-------------------------------------- -------------------SDEIIDHYHSLYIEELKNLYYENREK----YHAGNT----- ----ELKIVG--- >Naumovozymacastellii_YOR245C_XP_003674621 MSERDP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------STLSQQKSNNIRKR---------------------RSVVLDAIDAAAA------ ----DAEDHIIQ-------PSTSNSNART----NSQKRNKKPILDSCCSPTTPLKRR--- --LQTASVAWHLSSFVLFSVFTLYVLST-PLFWP-IVIPYMIY-FFID-KAPANGGVVTR YSVWFRSLTIWKYYCDYFPITLVKTTDIQPTFTPRKQTTNGNI------PPNGWKLR--- -----------------------------------------------LWPTHYSI----- ----------------------------NIMRRRN-QQTE-------------------- -------LEPTGPRYIFGYHPHGIGALGAFGIFGT--------------------EGRNW SQLFPGI-PVSLMTLVTQFHIPFYRDYLLAFGITAVSRKNSLKTLEK--------NQSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------SAVGSTELILNKRKGFVKLALKTG------NVGLVPVFGFGETDCYN IMRTKED------------SMLRRVQFWVKENCGFTIPIFYARGLFNYDFGLLPFRFPIT VVIGKPILVKE------KIANP-------------------------------------- -------------------SEEIVDYYHHLYVEELKKIYNENRDK----YGYAHQ----- ----ELKIVG--- >Candidaglabrata_YOR245C_CAGL0J03674g MFGN-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------AFHLRNRIHKR---------------------SSSSDRLDQDESSDDG--- ----DNAPNIVE-----------QKTKDI----KLVKPLKRPRLSNCCSPTTPMANR--- --LQTMAVAWHISSFVLFSIFSLLIISN-PFTWI-VVIPYLIY-FFND-RSPANGDVVYR YSPWVRSLKIWKYYCDYFPIELVKTVDLEPTFTPCNEEEEKEN----KKLQEYYTLR--- -----------------------------------------------LWPSDYEI----- ----------------------------RLFKKNTVYSHG-------------------- -------YKRTGPKYIFGYHPHGIGALGSFGAFAT--------------------EGRGW SNKFPGI-PVSLLTLVTQFHIPFYRDYLLSVGISSVSRKNALKVLDN--------NQSIC IVVGGARESLI------------------------------------------------- ------------------------------------------------------------ -------------SIPGTSGLILNKRKGFIKLAIQAG------NVSLVPVYTFGENDCYN ILATDET------------SIIRKLQLWVKENFGFTIPIFYARGLFNYDFGLLPFRAPLH VVVGRPIHVKE------QQENP-------------------------------------- -------------------EQSLVDHYHELYVEELKRIYLENRDR----YGYGAA----- ----DFEILG--- >Zygosaccharomycesrouxii_YOR245C_ZYRO0F07348g MD---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------EAIQDLRRR---------------------PVDHRSPTHKEE------- ---------------------------------VKGKLSSAPLLESCCSLRTPVPRR--- --IQTVAVAWYVSALAIILTCFLYSLAN-PFLWI-FSIPYTIF-FMFD-RTPGNGNVMSR VSPWFRSLPIWRRYCEYFPISLVKTANLEPTFTPRESKGERSP--------SSGSKW--- -----------------------------------------------FWRKWFN------ ------------------------------------SNDQ-------------------- -------LQRTGPRYIFGYHPHGVGCLGAFGVFGT--------------------EGCNW SKLFPGI-PVSLLTLVNQFQMPVYRDYLMALGVSAVSRKNSLKTLER--------DHSIC IVVGGARESLL------------------------------------------------- ------------------------------------------------------------ -------------QGVNTVDLILNRRKGFIRLALEAG------NVCLVPTFAFGEANCYN IIQPKNG------------SFWKKFQLWLKNNVGFTVPLFYARGLFNYDFGFLPYRTPVT VVVGKPIFVEK------RRETP-------------------------------------- -------------------TDEELDYYHGIYIQELKKIFYENRDK----YGFSDV----- ----ELRIVG--- >Vanderwaltozymapolyspora_YOR245C_XP_001646192 MSNGNDNI---------------------------------------------------- --DVVTVPKTGKS------------GIYEDHSLFEICYKKLSNSWNN------------- ------------------------------------------------------------ -----FKNSMFEETNGHKMF---------------------NTPYNSAISANVNASGVSH ---VVAAPNGIK-----------STKDKY----RDTESFETFTSESCCSIETPIARR--- --RQTIITAWQLTSMVLCLIFFLFSISI-PLFWF-ISIPYMTY-FLLD-KTPANGGVVKR YSPWLRSFGWWKEYCDYFPIRLHKTADLKPTFDVKHPKVD-----------LYYRLR--- -----------------------------------------------LWPTNYSI----- ----------------------------KIKKW-LTFSQS-------------------- -------YEKIGPKYIFGYHPHGVGALGAFGVFAT--------------------EGCGW SEKFPGI-PTSLMTLVTQFQVPYYRDYLLGFGITSVSKKNALKVLKN--------NHSIC IVVGGAMESLL------------------------------------------------- ------------------------------------------------------------ -------------SEVQKSDLVLKRRKGFIKLAINTG------DTCLVPTFAFGETNIYN ILQTKEG------------SFMRKLQLWLKENWGFTIPFFYARSVFNYDFGILPFRAPIN VVIGSPIYVKE------QNLNP-------------------------------------- -------------------TPEIVEHYQNLYIEELKKLYYENRDK----YGYGDV----- ----ELNIVD--- >Lachanceathermotolerans_YOR245C_KLTH0D11198g MCKTLNRT---------------------------------------------------- --------------------------------------KQLAERLLR------------- ---------------------------------GHLSWAEVDNT----ADGLKRSD---- -----GRTATMDNSKGLKQRGREGGRENGGEHGAE------HRDENAASERSSKASG--- --FLHHELDHVRLYDRN--HQEGKKLSEFV-EEINHFQEPRPKL-AFCSVKTPWRRR--- --LQTLAVAWHVASFVYILAFAILALAN-PIMWI-IMFPYMAY-YAFD-RSPANGNVTKR YSKWMRGLTFWRYYCDYFPIQLHKTADLKPTFTHKKHSSGCPS---EDKYLVSFQLR--- -----------------------------------------------LWPLRYSL----- ----------------------------KVNILKLGGAPP-------------------- -------REVTGPRYIFGYHPHGVAALGAFGAFAT--------------------EGANW SKLFPGI-PMCLMTLVNQFQIPFYRDYLLSLGVTTVSKKNALKVLER--------NHSIC IVVGGAQEALM------------------------------------------------- ------------------------------------------------------------ -------------SKLGSADLVLKRRKGFIKLALETG------NVCLVPCFAFGETDCYN ILETDEK------------SYLHKFQLWFKKTYGFTIPLFFARGLFNYDFGLIPFRKPIN VVTGNPIYIKR------KHDNP-------------------------------------- -------------------TVEEIDHYQKLYIDELQRTFDDYKRQ----FGYKDL----- ----ELNLAE--- >Kluyveromyceslactis_YOR245C_KLLA0F11165g MG---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------KEQIRKR---------------------QTKKVRKGSQPVA------ -----------------------NGKSSV----VGVSKDGKP---EFCAIDTPIERR--- --LQTLSVAWYVECIPLMIIIMLFVWVN-PLMWS-FVIPYTIY-YFID-RTASNGNAVKR HSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELEND--------ASEPGY--- -----------------------------------------------LDSSQPVL----- ----------------------------PDKWWNPFREKDET------------------ -------VRPTGPRYIFGYHPHGIAAFGAFGAFAT--------------------EACNW SKVFPGI-PVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEK--------NYSIA IVIGGASESLL------------------------------------------------- ------------------------------------------------------------ -------------TNLGSSDIILSKRKGFVKLALQTG------NVSLVPVYGFGETDTYK ILKLKND------------SIIGRIQIWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVN VVVGNPIHIKE------KIDHP-------------------------------------- -------------------TIEEIDHYHSLYIEELKRLYDDNKAK----FNYSEK----- ----TLNIVE--- >Eremotheciumgossypii_YOR245C_NP_983542 MQDSMD------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------DSLREAE---- -----GRQDDSEVSSGTTLGS--------------------STPEDSGVTAKLRKKYQMA SALLRRELEELSVYDA---KTAGVSGRSSG-SGSGGLALLGGRF-HVAPLRIPARRR--- --LQTLVVAWHTSSFIYMTVLVLFLAAN-PLMWW-FMVPYMVY-YVWN-RSPANGGVVRR YSPRLRSLALWRYYCEYYPISLHKSEDLAPTFVPDPRGAEPRE--------WKLRLW--- -----------------------------------------------LWPTRVEL----- ----------------------------LNLTLQWTRARP-------------------- -------QVATGPRYIFGYHPHGVGALGAFGAIAT--------------------EGCNW SKVFAGI-PACLCTLVNQFQIPIYRDYLLGLGCTSVARKNVLKVLEQ--------NYSVC IVVGGAQEALL------------------------------------------------- ------------------------------------------------------------ -------------SRVGSTELVLNKRKGFIKLALETG------NVNLVPIYAFGETDCFN VLDTGNE------------SYLRKFQLWIKKTYGFTIPFFFARGVFNYDFGFLPFRNPIN VVVGKPVYVDK------RRTNP-------------------------------------- -------------------TMEEIDHYHDLYVQELRNVFDKNKHK----FGYAGK----- ----ELKIVE--- >Komagataellapastoris_YOR245C_XP_002492428 MPEKK------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----NSRSADEALSFLAKTN-------------------VERPMHYSKTGNITPDT--- ---VSSREDHYQDYDDSQDDIINNKLLQR---RQGGPHNKIEKQRRFALLRSSLNRR--- --LETLVILWHTITIPFLASLFFVLCTI-PMLWP-LIIVYLVY-FYIDANTPSNGKSADR RVEWFRSLHIWKHFVNYYPISVYKTVDLEPTFKTKKIEII---------LPKYHQVT--- ----------------------------------------------TYLPSSVR------ ----------------------------KYIPTHRVLIEK-------------------- -------EIKTGPRYIFGYHPHGVVSLGITGAFGT--------------------NGCNI GELLPGI-RIYLLTLITQFKLPLLRDYLMALGISSVSKRNVTALIKR--------NQSVC IVIGGASESLL------------------------------------------------- ------------------------------------------------------------ -------------SKPHTIDIVLKKRKGFVKVALELG------DTELVPVFGFGENTAYN VFDPSVSGKSCSVLN-YVRKQMCGFQLWLKQHFGFTFPFFHARGVFNHDFGLLPYRKPIN LVIGRPIPVP-------YIHSP-------------------------------------- -------------------TQEQIDHYHSLYVEELKRVFEQNKER----FNAGSL----- ----ELRIVE--- >Ogataeapolymorpha_YOR245C_ESW99385 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MSNWGLYKHFANYYPVRLHRSKELSPTKTPIKVELEEFDI-----PPLFASVT--- --------------------------------------------PNFLLSSLFRW----- ----------------------------KVIQKRKKTVER-------------------- -------ETITGPRYIFGYHPHGVIAMGVFAGFAT--------------------EGAGF SKLFPGI-RCFVTTLVNQFQLPFYRDYLMSLGCTAVTKKNISSLLDK--------GHSVV IVVGGASESLL------------------------------------------------- ------------------------------------------------------------ -------------AKPHLNSIVLKRRKGFVKLALQASGRFNNDDICLVPVYAFGENNIYD VYYTNETENSNNKNDGYIRQLLKWFQLRLKKNFGFTLPIIVSRGLLNYDFGLLPHRRPIH IVTGAPITVRR------LHGRKYGD----------------------------------- -----------------VVSPEEIDYYHSLYVQALQELFATYKDK----YLLEHDR---- ----DLNIVE--- >Yarrowialipolytica_YOR245C_YALI0E32769g M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------TIDSQYYKSR----DKNDTAPKIAGIRYAPLSTPLLNR--- --CETFSLVWHIFSIPTFLTIFMLCCAI-PLLWP-FVIAYVVY-AVKD-DSPSNGGVVKR YSPISRNFFIWKLFGRYFPITLHKTVDLEPTHTYYPLDVQEYHLIAERYWPQNKYLRAII STIEYFLPAFMKRSLSINEQEQPAERDPL-LSPVSPSSPGSQPDKWINHDSRYSRGESSG S----NGHASGSELNGNGNNGTTNRRP-LSSASAGSTASDSTLLNGSLNSYANQIIGEND PQLSPTKLKPTGRKYIFGYHPHGIIGMGAFGGIAT--------------------EGAGW SKLFPGI-PVSLMTLTNNFRVPLYREYLMSLGVASVSKKSCKALLKR--------NQSIC IVVGGAQESLL------------------------------------------------- ------------------------------------------------------------ -------------ARPGVMDLVLLKRKGFVRLGMEVG------NVALVPIMAFGENDLYD QVSNDKS------------SKLYRFQQFVKNFLGFTLPLMHARGVFNYDVGLVPYRRPVN IVVGSPIDLP-------YLPHP-------------------------------------- -------------------TDEEVSEYHDRYIAELQRIYNEHKDE----YFIDWTEEGKG A--PEFRMIE--- >Geotrichumcandidum_YOR245C_GECA18s00813g MP---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------ISFAPLTTPLQRR--- --LQTLAVVWHVFTIPSLLGLFLFLCSF-PPLWP-LIIVYLIYFVFFDSKSHENGASIKK VSPFLRNALLWKYFSDYFPITLYKTHELAPTFVSANEAAAISQP-----IPKSPRLEATI VDDDSI---------------DPTDSTDFTISE------KGDIDDESSADKKYQIIQSSR EFQELQGHFGVRVFLKELVAWLLSFLPFVTKTNQGSHAAD-------------------- -------LKRVGRQYIFGYHPHGIISMGAMGGIAT--------------------EGSNW SRLFPGI-PVSTLTLITQFQLPLFREYLLSLGFASVSKRSCTTLLKQ--------GQSIC IVLGGAQESLL------------------------------------------------- ------------------------------------------------------------ -------------ARPGQLNLVLNKRKGFVKLAMTVP------NTTLVPTLAFGENDVYD QVSNDEH------------STLYKIQDFLKRKLGFTLPLLHARGIFNYDFGIIPYRRPIN IVIGEPIDMP-------YRSNP-------------------------------------- -------------------SEAEVDYYHRLYVSKLKKIYDDFKDK----FHKDLTGNFGN CVYTDLEAVA--- >Neurosporacrassa_YOR245C_XP_965438 MADASGPLPPRSGSLSRKKSGKKNKKNNQKAAHTQTSASADQASGTPANQKEKQLHTKTS IPDLK--PSTTSVDSTATASASASLGSLNTKASHEKP-AKMSNKDKRAVTDESADFSISD PATTNPATPSSTQVDGVLETDTPRTEVSQTAGTAPSTGI---DYADALKDALKESG---- -----TKEGTEERVEDLPQEG---AREEPAEKAAKKTVLPIHDNTAREEPSNADHDV--- ---RREKQALYDEYPSLYFEGSDNELAQM---ERDRANAYQAAGIRFAPFNIPLQRR--- --LQTLAVLLHSLIIATTVSFFFFLCAI-PLLWP-LVIPYLLH-MLLS-KAASDGKLRFR -SERFRHSRIWHFFADYFPAKLHKTHDLPAD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------RKYIFGYHPHGIISHGAYAAFAT--------------------EALGF SEKFPGI-TNSLLTLDSNFRIPIYRDYILSMGLRSVSKESITNILSRGGTDGHGAGRAVT IVIGGARESLE------------------------------------------------- ------------------------------------------------------------ -------------AQPGTLRLVLGERKGFVKVAMRTG-------ADIVPVLAFGENDLYD QVSPKSH------------PYLHRLQMFVLRTLKFTLPFLHGRGIFNYDVGLMPYRRPLN IVVGKPIRVTK------RAESD-------------------------------------- ------------------LETSEIDQLHGLYVKELEKMWERYKDG----FAPERIE---- ----EMQILK--- >Aspergillusfumigatus_YOR245C_XP_749138 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MRSLSIWSLYASYFPACLHRSEALLPT----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------RKYIFGYHPHGIISHGAFAAFAT--------------------EALGF SRLFPGI-TNTLLTLDSNFRIPFYREYALAMGLASVSRESCENLLSKGGADGEGMGRAIT IVIGGARESLH------------------------------------------------- ------------------------------------------------------------ -------------ALPHSLRLVLKCRKGFIRLAIRTG-------ADLVPVLAFGENDLYE QVRSDQH------------PIIHKLQMLIKRTMGFTVPLFHARGVFNYDVGLMPYRRPLN IVVGRPIQVVQ------QRDRD-------------------------------------- -----------------KIDETYIDDLHAKYIQELRRLWEQYKDV----FAKDRIS---- ----EIEIVAD-K >Cryptococcusneoformans_YOR245C_XP_571235 MPLKRPSPGPH-----------------------------------PL------------ --DLN--P-------------------------YERL--QFEEKENRRSHNDTD------ ------------------------------------------------------------ -----HHATLTSRQEGLRRRA------------ALGENVDISADGESKEDEGYSAEK--- ---RNDRLSSPEDTKTGEGKGKKSPLMSNLKLDDFRDTLEAGIERKFAPLHIPPHRR--- --LQTAAVALWALLLPICMIVLLLLLSL-PPMWL-ILIPYFIW-ISFD-RAPIHGG---R PKEWARKGFIWKYFADYYPCSIVKEAELPPN----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------RPYLFGYHPHGIIGMGAFATFAT--------------------EGTNF SEYFPGI-KPHLLTLGSNFKIPFYRELLMIHGCGSVSKRSCANVLSQG------PGSAIA IVIGGASESLS------------------------------------------------- ------------------------------------------------------------ -------------AHPGTADLTLKKRFGFVKMAIREG-------ADLVPVFSFGENDIYA QLANAKG------------SMVYKLQKKFEKVFGFTLPLFYGRGLFNYNYGLMPFRHPIV SVVGKPIHVE-------RDPHP-------------------------------------- -------------------SDEKVQELQSKYIAELTRIWDKYKDL----YARGRTK---- ----ELTLVE--- >Schizosaccharomycespombe_YOR245C_XP_001713160 MS---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------EETSIPGIIASTPPISKDSRRNVS HWLQALAVFLHSVSLTLTASWYTVLWAF-LPFWP-FLIVYLIW-LIYD-DGFVTGK--DR QKRWLRNAPPYRWFCHYFPIRLHKTTELDSE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------KNYIFGYHPHGIISLGAFGGFAS--------------------EGADF SKLFPGI-NVSVLTLNSNFYVPVYRDYLMALNINSVSKKSCVSILSRK------PGDSVL IVIGGAQESLL------------------------------------------------- ------------------------------------------------------------ -------------SRPGQNNLVLKKRFGFVKLAFLTG-------SSLVPCFAFGESDIFE QVDNNPR------------TRIYKFQEIVKKIAGFTVPFFYGRGLLNKTFGLMPWRKPIN IVVGEPIDVP-------KKSHP-------------------------------------- -------------------TNQEIYEVHEEYIRRLEGLWNKYKDV----FLPNRIS---- ----ELKLSA--- >Candidaalbicans_YOR245C_XP_712742 MT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------DTSDLKPEHTEKATG--- -----LSTSKEVPESTLTQR---------------------KQPSTP------------- -----------------------ATQTSK----RPTPAKKKRAFINVAPLNTPLSHR--- --LETLGVVWHCISIPFFICLFFFMISLGLFGWIVIVLPYFIWWYGFDLHTPTNGKVAYR YRNSMKNFIIWDWFVRYFPIKVYKSVELEPTFKEVLVEETESS----------------- ---------------------EDDDEQDL-VSE----------RSRTLVDKVFKFFGLKK RLNDTSS--------------------------GKSETYK-------------------- -------TVSTGPRYIFGYHPHGVISMGGVGLFATNSLRNEPYTPFLKFLKPFFHDSSKG ERLFPGLGNIFLLTITTQFAIPFYRDYLMGLGVTSASAKNIRSLISNG-------DNSVC IVVGGAEESLLNNMVAKHARVGYGYKEN-QDINGSDAED--------------------- --------------------------------------DQPEEEEQQQQQQPNGSVEVDK KTTKEVGEKTSSQPSKREVKLILNKRKGFVKLAIELG------NVALVPTFAFGEADVYR LVQPSPT------------SMMYKFQKWMKGIFSFTIPLFSARGVFIYDYGLLPFRNPIN ICVGKPIYIPAGALQEYKQQHPEEFTEEETKPPMKKSGSF-----TDIFK---------- ----MNGETPKVSTIKTKIPPALLDKYHKLYVDELRNVYEENKHK----FGYGDV----- ----EFSIVE--- >Millerozymafarinosa_PISO0H12899g MP---------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------EDLSIQPE--- -----VDENKTANEQEIRNR---------------------KQSKKT------------- -----------------------SRNERY----GEDDTTSKKYGFHVAPLNTPLENR--- --LQTLGIMWHCMSIPFFVSLFLIVLSLGWVAWLTIILPYFIWWYGFDLHTPTNGKAAYR PKDWMRNLIVWQWFVSYFPIEVHKSCDLAPTYTEVMVEDNT------------------- ---------------------EPDDEEDL-ISE----------DTRTNIDKLFMKLGLSK RLNDFDSTKIVD---------------SQADKKKGNFKIT-------------------- -------KVSHGPRYIFGYHPHGVISMGVMGTFATNIIRNEPFEPPLKCLRAFFYDPANK EKLLPGIGNVFPLTLTTQFTLPFYRDYLMSLGLTSASGKNIKRIINNG-------DNSVC LVVGGAQESLLNDVVASHSRRGKKYKEDSKNEKAARSEE--------------------- --DEGK-------------------------SDELPTADQ-------------------- ------------KNSSKEIRLVLNKRKGFIKIAIELG------NISLVPTFGFGEADIYR VKQPKPG------------SIGSKFQKWMKSTFQFTVPFFSARGVFLYDFGLLPYRNPIN ICMGRPIHVPKEALQDYLKEHPAFE----------------------------------- ----KDHLDTKKATGKIQVPPELVDHYHKLYVDELKRVFEENKGN----YGYDDV----- ----ELKIIE--- >Millerozymafarinosa_PISO0G12898g MP---------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------EDLSIQPE--- -----VDENKTANEQEIRNR---------------------KQSKKT------------- -----------------------SRNERY----GEDDTTSKKYGFHVAPLNTPLENR--- --LQTLGIMWHCMSIPFFVSLFLIVLSLGWVAWLTIILPYFIWWYGFDLHTPTNGKAAYR PKDWMRNLIVWQWFVSYFPIEVHKSCDLAPTYTEVMVEDNT------------------- ---------------------EPDDEEDL-ISE----------DTRTNIDKLFMKLGLSK RLNDFDSTKIVD---------------SQADKKKGNFKIT-------------------- -------KVSHGPRYIFGYHPHGVISMGVMGTFATNIIRNEPFEPPLKCLRAFFYDPANK EKLLPGIGNVFPLTLTTQFTLPFYRDYLMSLGLTSASGKNIKRIINNG-------DNSVC LVVGGAQESLLNDVVASHSRRGKKYKEDSKNEKAARSEE--------------------- --DEGK-------------------------SDELPTADQ-------------------- ------------KNSSKEIRLVLNKRKGFIKIAIELG------NISLVPTFGFGEADIYR VKQPKPG------------SIGSKFQKWMKSTFQFTVPFFSARGVFLYDFGLLPYRNPIN ICMGRPIHVPKEALQDYLKEHPAFE----------------------------------- ----KDHLDTKKATGKIQVPPELVDHYHKLYVDELKRVFEENKGN----YGYDDV----- ----ELKIIE--- >Debaryomyceshansenii_YOR245C_DEHA0C13101g MSHN-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------SSPE--- -----SNTTSDDKKQQLRRR---------------------HGSHDTPSENDSR------ -------------------RSSRSSTKSN----TKPKTHRKKSFVNFAPLNTPLHNR--- --LETMGVIWHCLSIPFFVSLFLLAISLGWIIWIFVILPYFIWWYFFDLHTPTNGKIVYR VKDWMKNIIIWEWFVNYFPISVHKACEFEPTFTQMLVDDNE------------------- ---------------------GNDDEEDL-ISE----------DSRTLLDKLFKTLGLRK RLNDSDSHNVSNT-------------TSSDRKFDKALKYK-------------------- -------KESTGPRYIFGYHPHGVISMGVMGAFATNVIRNEPYQPPFSFLKSFFHDPSKY TRLLPGIGNIFLLTLTTQFTLPFYRDYLMSLGLTSASYKNIKSLINNG-------DNSVC LVVGGAQESLLNTMVSPRSRIGNGYKKDETDESGDESEPMVKEYNPKEVQHYSMKEQMDK ISDEKKQESSESDSNSDTEKGQKKLENEKLIKTETEDADQPEENKNKSFNDHNGTETENS GQGKEKESQRDDPSSPRQIQLVLNKRKGFVKLAIELG------NVCLVPTFGFGEADIFR IANPKPG------------SLGSRFQEWMKSTFQFTVPFFSARGVFIYDFGFLPFRNPID ICMGEPIYVSSGLIADYKLKHPGFDSDEEVEQKNKQKKEYEKEDETDSKKKDKKDSKKKG KKDFEDKKDSKKREKKIKIPSEILNHYHKLYVDGLKKVYEENKGK----FGYEDV----- ----ELIIIE--- >Meyerozymaguilliermondii_YOR245C_EDK39486 MTKEVDESTGGASDIPNMVEEAK-------------SSSFDR-------ETEENSLSETT KPDENSVPESTKHD--------------------EKLVPEITKHEDNPMEND-------- -------------------------QVSQNTATSPMTGAGSEETRDLITENIEKPDEGDS LIELISKDNDGDGDDGLKNR---------------------KQKRSS-SEVKRS------ -------------------RMSSSAPKGP-----TPQKHERPKYINVAPLNIPIRRR--- --LEMVGIIWHTICIPTFVSLFFLTLSLGPFAWVGVILPYFLWWYLIDLHTPTNGKVAYR SRDWMKNFIVWDWFVDYFPIRVHKSCELEPTFSDVIIEDDV------------------- ---------------------VPDDEEDL-ISE----------QSRTGVDKLFKFLGLRK RLND-DSDASSQC-------------SSSQESLSTRRKVK-------------------- -------RMSTGPRYIFGYHPHGVISMGVFGTFATNALRNEPYEPPLRLLKPFFHDSSKG ERLFPGIGTVFPLTLTTQFIVPYYRDYILGMGLTSASAKNIKSLISNG-------DNSIC VVVGGAQESLLNDMVAATTVPGRYGKSNLPNDSDTDSEF--------------------- --DPQR-------------------------KIE--ENKE-------------------- ------------ETGVKKIELVLNKRKGFVKIAIELG------NVSLVPTFGFGEADIYR ITKPKPG------------SFGEMFQSWMKRTFQFTVPFFSARGVFIYDFGFLPYRNPIN VCFGRPIHIPAGLLDQYKEPETEKDEKEKE------------------------------ -----------------------------------KNVFQFTQDKQAPAFNIQSIQVFQG ----EATIKEETS MAFFT TAZ1 >Saccharomycescerevisiae_YPR140W -----------------------------------MSFRDVLERGDEF-LEAYPRRS-PL WRFLSYSTSLLTFGVSKLLLF-TCYNVKLNGFE------------------K-LETALER SKRENRGLMTVMNHM-------------------------------SMVDDPLVWATLP- YKLFT-------SLDNIRWSLGAHNICFQNKFLANFFSLGQVLSTERFG----VGPFQGS IDASIRLLSPDDTLDLE--WTPHSEVSSSL-------------KK--------------- ----------------AYSPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGITRMI LEATKPPIVVPIFATGFEKIASEAVTDSMFRQILPRNFGSEINVTIGDPLN-DDLIDRYR KEWTHLVEKYYDPKNP--------------------------NDLSDELKYGKEAQDLRS RLAAELRAHVAEIRNEVRKLPREDPRFKSPSWWKRFNTTEGKSDPDVKVIGENWAIRRMQ KFLP------PEGKPK--GKDD---------------------------- >Saccharomycesparadoxus_YPR140W_Spar_16.507 -----------------------------------MSFRDVLERGDEF-LEAYPRRN-PL WRFLSYSTSLLTFGVSKLLLF-TCYNVKLNGCE------------------K-LEAALEC SKTENRGLMTVMNHM-------------------------------SMVDDPLVWATLP- YKLFT-------SLDNIRWSLGAHNICFQNKFLANFFSLGQVLSTERFG----VGPFQGS IDASIRLLSPDDTLDLE--WTPHSEGPRSL-------------KKIRE------------ ----------------TYSPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGITRMI LEATKPPIIVPIFATGFEKIASEAATDSMFRQILPRNFGSEVNVTIGDPLN-DDLIGRYR KEWKHLVEKYYDPKNP--------------------------NDLSDELKYGEEAQNLRS RLAAELRSHVAEIRNEVRKLPREDPRFKSPSWWKRFNTTEGKSDPDVKVIGENWAIRRMQ KFLP------SE--PK--RKDD---------------------------- >Saccharomycesmikatae_YPR140W_Smik_16.387 -----------------------------------MSFRDVLERGDEF-LESYPRRN-PI WRLLSYSTSLLTFGVSKLLLF-TCYNVKVNNFE------------------K-LETALER SKSENRGLMTAMNHM-------------------------------SMVDDPLVWATLP- YKLFT-------SLDNIRWSLGAHNICFQNRFLSNFFSLGQVLSTERFG----IGPFQGS IDASIRLLSPDDTLDLE--WTPHSEGSCLL-------------KNTKE------------ ----------------NYAPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGITRMI LEATKPPIIVPIFATGFEKIASEAATDSMFKQILPRNLGSEVNVTIGDPLD-DDLIDRYR KEWQHLVKKYYDPKNP--------------------------NDLSDELKYGEEAQNLRS RLAAELRSHVAEIRNEVRKLPREDPRFKSPSWWRQFNTTEGKSDPDVKVIGENWAIRRMQ RFLT------PENKPR--RKDD---------------------------- >Saccharomyceskudriavzevii_YPR140W_Skud_16.434 -----------------------------------MSFKNVLERGDEF-LESYPRRN-PI WRFLSYSTALLTFGVSKLLLF-TCYNVKVNDFE------------------K-LEAALER SKNENRGLMTVMNHM-------------------------------SMVDDPLVWATLP- YKLFT-------SLDNIRWSLGAHNICFQNKFLANFFSLGQVLSTERFG----VGPFQGS IDASVRLLSPDDTLDLE--WTPHSEDSRFP-------------KKTGE------------ ----------------NYTPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGIARMI LEATKPPIVVPIFATGFEKIASEAASDSMLRQILPRNFGSEINVTIGDSLD-DNLIDEYR KEWRHLVEKYYDPKNP--------------------------NDFSDELKYGEEAQNLRS RLAAELRSHVADIRNEVRKLPREDPRFKSPSWWKRFNTTEGKSDPDVKVVGENWAIRRMQ KFLP------SENEPK--RKDN---------------------------- >Saccharomycesarboricola_YPR140W_EJS41281 -----------------------------------MSFRDVLERGDDF-LETYPRTN-HI WRFLSYSTSLFTFGVSKLLLF-TCYKVELNGCE------------------K-LETALER SKNENRGIMTVMNHM-------------------------------SMVDDPLVWATLP- YNLFT-------SLDNIRWSLGAHNICFKNKFLANYFSLGQVLSTERFG----AGPFQGS IDASIRLLSPDDTLDLE--WTPHSEGSGSP-------------TKVRE------------ ----------------NYTPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGITRMI LEATKPPIVLPIFATGFEKIASEAATDSMFRQILPRNFGSKINVTIGDPLD-DNLIDRYR EEWRQLVEKYYDPKNP--------------------------SDLSDELKYGKEAQNLRS RLAAELRSNVAEIRNEVRKLPREDPRFKSPSWWKRFNTTEGKSDPDVKIIGENWAIRRMQ KFLP------SEDNPK--RKDD---------------------------- >Saccharomycesbayanus_YPR140W_Sbay_16.468 -----------------------------------MSFNDVLERGDEF-LEAYPRRN-PF WRFMSYSTSLLTFGVSKLLLF-TCYKVKLNGYE------------------K-LESALER SKDENRGLMTVMNHM-------------------------------SMVDDPLVWATLP- YSLFT-------SLDNIRWCLGAHNVCFQNKFLANYFSLGQVLSTERFG----VGPFQGS IDASIRLLSPDDTINLQ--RSSHSESSASP-------------AKIQD------------ ----------------TYTPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGITRMI LEATKPPIVVPIFATGFEKIASEAAKDSMLKQILPRNFGTELNVTIGDPLD-DDLIDRYR NEWKHLVEKHYDPKNP--------------------------NDLSDELKYGEEAQDLRS RLAAELRCHVAEIRNEIRKLPREDPRFKSPSWWRRFNTTEGKSDPDVKVIGENWAIRRLQ KFLP------SKDDPN--CKDD---------------------------- >Lachanceathermotolerans_YPR140W_KLTH0F14476g -----------------------------------MSLPDVLNRGDEF-LSEYPRRS-RL WQIGSHATCLLTVGISKLVLK-TCYNTQLNHFE------------------K-LESAIER SVSENRGLMTVMNHM-------------------------------SVVDDPFIWGVFP- WRMYR-------DLDHIRWCLGAHNVCFQSKFLATFFSLGKVLSTERFG----AGPFQGS IDASIRLLSPDDTLDLE--WTPHHVDCPEP---LRSPPL--VQKITK------------- ----------------EYIPPVARTKPSWVHVYPEGFVLQLHPPYANSMRYFKWGITRMV LESTKAPIVVPIFTTGFEKIAPESAAGTKIERYLPRNFGAEVNVTVGDPVN-DSIIERYR EEWRRLVEKYHDPQNP--------------------------TDLTQELKTGTEAQALRS KLAAELRKHVAQIRHDQRGFPQEDEKFQSPKWWKLYTQTEGSSDPSVEFIGKNWAIRRLQ KFLR------EQEENG--DLEKNGP---------------------NSKK >Kluyveromyceslactis_YPR140W_KLLA0B10978g -----------------------------------MSFPDVLDRGDEF-LSQYPRTN-PF WQIASHGTCLLAVGISKFMLN-TFYNVKLNNLE------------------K-LQEAVAR TKTENRGLMTVMNHM-------------------------------SVVDDPFIWGVFP- WSMYW-------DLDQIRWCLGAHNVCFQNKFLATFFSLGKVLSTERFG----GGPFQGS IDASIRLLSPDDTLDLE--WTPHHIE---P---LKKEIE--KQPTLEGNNK-IFD----- ------KLSVKDGHVVKYVAPVARSKPSWIHVYPEGFVLQLQPPFSNSMRYFRWGITRLI LESTKSPIVVPMFSTGFEKIAPESSAGTMIERYLPRNMGAEINVTIGNPID-DAIIDGYR KEWLALCDKYHDPKNP--------------------------TDLSWELKYGKEVQDLRS RLAAELRAHVAKIRHEERRFELEDERFKSAAWWGRYTETEGASDPDVKFIGQNWAIRRLQ KFLN------DYDDAE--NPGKHE-------------------------- >Zygosaccharomycesrouxii_YPR140W_ZYRO0B04312g -----------------------------------MSLPDVLSRGDDF-LAQYPRRS-SA WQFFSHGTCLATIGLSKLILK-AFYNVELNHFN------------------K-LERAIDR SKDENRGLLTVMNHM-------------------------------SCVDDPFLWAVFP- WRIYR-------DVDTIRWCLGARNVCFQNKVFGTFFSLGKVLSTERFG----ASPFQGS IDAAVRLLSPDDTMDLE--WFPPSEKVSKP---AEAVIN--MAKKAKE------------ ----------------NYFPPVKRSRPAWMHVYPEGFVLQLHPPFSNSMRYFKWGVSRMI LESTVAPIVVPIFTTGFEKVASEETAGTMIKRYLPANFGAEINVTIGDPIE-DSIIEGYR QEWKKLVEKYHDPEHP--------------------------TDLSPELIEGKEAQGLRS AVAAELRNHIAKIRHEQRNFPKEDPRFESPSWWKNYTATEGDSDPDVRFIGLNWAIRRLQ SYLP------ENNNNT--NDDTNNK---------------------KNS- >Eremotheciumgossypii_YPR140W_NP_986920 -----------------------------------MSLPDVLRRGDEF-LSEYPRQS-VL WQWASHGTCMATIAASKAFLK-LFYNVRLTHVD------------------K-LENALER TVAENRGLLTIMNHM-------------------------------SVVDDPFLWAALP- WRIYR-------HMDQMRWCLGAQNVCFQNRGLAAFFSLGRVLSTERFG----AGPFQGS IEASIRLLSPDDTLDLE--WTPHCEK---P---LESPQL--LEPMRKV------------ ----------------EYIPPVRRVRPSWVHVFPEGFVLQLEHPHANSMRYFKWGITRMV LESTKPPIIVPIFATGFEKIAPESAAGTVVERYLPRNFGAEINVTIGDTVD-DNIIESLR AEWRSLVEKYHDPENP--------------------------TDLTPELRDGQEVRDLRS RVAAILREHVAAIRHENHGLPLEDERFKSPAWWKKYTHTEGESAKDVRFIGQNWAIKRLQ EPSR------DYSDPI--SSSNNDD---------------------RKK- >Naumovozymacastellii_YPR140W_XP_003677183 -----------------------------------MTFPDVLKRGDEF-LKEYPRQS-RM WRFLSYSTCLITLGFSKLIMS-TFYNVKVNNLD------------------K-LQDALKR AEKENRGIMTIMNHM-------------------------------STVDDPTFWAAFP- WKLYNW------NPDNVRWCLGAENICFSNKLLGYFFSLGQVLSTKRFG----VGPFQGS IDASIRLLSPDDTINMN--WTPWGQVKE---------------YFAPA------------ ----------------GYQPPVKRNKPAWVHVYPEGFVLQLHPPYANSMRYFKWGITRMV LEATRPPIVVPIFTTGFENIINEGSKESFFKQ-IWKSIGTEINVTIGDPLD-DSIINLVR EEWDDLVKKFYDPEKP--------------------------TDLSTRLKYGEEAQQLRS KVAAILRDNVAKIRDQERKFPPEDPRFKSPAWWKRFTTTEGKSDPDVKFIGQNWAIRRLQ TFLNI-DEKKKHNEGK--NEEKPNR---------------------KEE- >Vanderwaltozymapolyspora_YPR140W_XP_001644119 -----------------------------------MAFPDVLQRGDDF-LSEYPRNS-KI WKAFSYGTCVFTIGMSKLILK-SLYNVELNHFH------------------E-LEHAIDR SHKEERGLMTIMNHM-------------------------------SVVDDPFIWAVFP- WRTYK-------NLQNMRWCLGADNVCFTNKYVGTYFSLGQVLATKRFG----TGPFQGS IEAMIRLVSPIESC-------PSSD----------------------------------- ----------------NFSPTFKIAKPAWIHVYPEGFVLQLNPPFSNSMRYFKWGITRVL LESTKAPIVVPIFTTGFEKVAPEDTAES-YSRFLPNNIGADIKVTVGKPID-DKVIEEYR QEWNTLVEKYTDPRNP--------------------------TDLSDELKYGKDAQELRS KVANMLREHVANIRHEKCNFPKEDERFKSPTWWKRFTVTEGDSDPDVKFIGKNWAIRRLQ KFLA------DRDNEDDINTKKNND---------------------NEGK >Candidaglabrata_YPR140W_CAGL0D04972g -----------------------------------MSFYNVLKNGDDM-LREYPRRS-II WRILSYGTCLFTYGVSRMILS-TLYNFKVFNFE------------------R-LENAMKR SKAENRGVLTIMNHM-------------------------------SMVDDPFVWATFP- IRFYS-------SVDRFRWCLGAENICFQNAALSYFFSLGKTLSTRRFG----AGPFQDS IDATVRLFSTDETLLKD--KDP-------------------------------------- ----------------NYKPPVRQKSPPWVHIYPEGFVLQLQPPHSNSMRYFRWGVARTI LESTVPPIIVPIFSTGFEKIASEEAKG-MMRQLMPRNYGSKIKVTIGEEIS-DEIIFRYR KEWQVLVEKYKDCNNP--------------------------DEMPDELKYGEEAEDLRS RLAAELREHVAKIRHDECHFPEEDPRFKSVSWWKKFNCSEGESDPDVKIIGKNWAIKRLQ THLK------NNENTK--DH------------------------------ >Kazachstaniaafricana_YPR140W_XP_003956089 -----------------------------------MVFTDVYKRGDDF-LAEYPRRS-PF WRFLSFSTNILVLCVSKMILK-TFYNVKLNDFD------------------H-LENAMKR AKDENRGIITIMNHM-------------------------------STLDDPLLWACFP- MKTYS-------NLSNMRWCLGANNICFANKALSTFFSLGQVLSTERFG----VGPFQGS IDAAIRLLSPDDTISK---------------------------LFQDE------------ ----------------NYNPPIIRNKPSWVHIYPEGFVLQLHPPYANSMRYFKWGMTRMI LEPTKPPIVVPIFTTGFEKLAPEDKEDQSLLKNLYNAIGTEINITVGKPID-DEVIDSYR SKWMDLIIATH-AEQE--------------------------TDLTDELKNGTEAKLLRS RLASELRLHVANIRHHKRFLPMEDLRFGRPEWWKIFTKTEGSSDPDVEFIGENWAIRRLQ KFLN------ENQLKI--NNSDDDDIVNSDGTTESDGSTYVTDSDDKKNN >Candidaalbicans_YPR140W_XP_714267 MSNHKKKIYGIEKKNIIKIPFQDKHSKKRPSFYFAMSFQDVLKRGDEF-LNDYPRTN-PF WNLASHATCLFMITGSKIILN-TFYKPVLHNIE------------------K-LDNALQR ARDENRGLLTVMNHM-------------------------------SVVDDPAFYASLP- WRYHL-------DIDTIRWGFGAHNICFSNVFQSWFFNLGKILGTKRFG----EGPFQGS LDAAIRILSPDDTLDLE--FTPGIKDEQKA-------------VVLQTVNN-ITDCRNKE -LVKFIKPAPESTNVLMSKNPFIRTKTSWFHVFPEGFVLQLQEPHNNSMRYFKWGVSRLI LESTRTPIVVPLFSFGFEKVAPEDSAEEGLKRWLPANFGAEIHVCIGDPIK-DDVLESYR EQWRSLVSKYVDKSNP--------------------------TDLSDELKTGSKAQSLRS DLAGYLREKVLEIRNEIGLFNPEDKRFKDPKFWKLFTNTEGLSDPSVKFVGKNWAIKRLQ SHLP------EYDPSE--DTKN---------------------------- >Millerozymafarinosa_YPR140W_PISO0M23574g -----------------------------------MSFQDVLKRGDDF-LTEYPRRS-KL WNYASHAVCLFMILQSKALLH-LLYTPEVHNIE------------------N-LDNALAR ARRENRSLLTVMNHM-------------------------------SVVDDPAFFAALP- MRFHT-------DIDTIRWGFGAHNICFSNKFLSWFFNFGKILGTKRFG----EGPFQGS LEAAIRILSPDDTLDLE--FGPLVRNEEKP-------------LLIQQANN-GQDKLDIE KLAPQVQPSSSSTNLLMSKSPFIRNKTSWFHVFPEGYVLQLHSPHNNSMRYFKWGVSRLI LESTRAPIVVPVFTYGFEKVAPEDSAEKGIFRYLPANLKSEIHINIGSPID-DATIEGYR TRWRDLCKKYIDPRNP--------------------------SDLSEELKYGSEACSLRS EVAARLRDAVSSIRESLHVFNKEDPRFKEPAFWKRYTLSEGASDPDVKFIGKNWAIRRFQ KHLP------EYNADE--E------------------------------- >Millerozymafarinosa_YPR140W_PISO0N23839g -----------------------------------MSFQDVLKRGDDF-LTEYPRRS-KL WNYASHAVCLFMILQSKAILH-LLYTPVVHNIE------------------N-LDNALAR ARRENRSLLTVMNHM-------------------------------SVVDDPAFFAALP- MRFHT-------DIDTIRWGFGAHNICFSNKVSSWFFNLGKVLGTKRFG----EGPFQGS LEAAIRILSPDDTLDLE--FGPLVRNEEKP-------------LLIQEAGN-GQGKLDVE KLAPQVQPSSSSTNLLMSKSPFIRNKTSWFHVFPEGYVLQLHQPHNNSMRYFKWGVSRLI LESTRAPIVVPVFTYGFEKVAPEDSAEKGINRYLPANLKSEIHINVGSSID-DATIESYR KRWRDLCKKYIDPRNP--------------------------SDLSEELKYGSEACSLRS EVSARLRDAVSNIRESLHVFNKEDPRFKEPAFWKRYTLSEGASDPDVNFIGKNWAIRRFQ KHLP------EYNGDE--A------------------------------- >Debaryomyceshansenii_YPR140W_DEHA0B02024g -----------------------------------MSFQDVLKRGDDF-LNEYPRTS-RL WNYASHATCLFMILQSKLFLN-VLYNPHLHNIE------------------K-LDRALEK ARSENRSLLTMMNHM-------------------------------SVVDDPTFYAALP- FRFHT-------DIETIRWGFGAHNVCFSNKALSWFFNLGKILGTRRFG----DGPFQGS LDAAIRILSPDDTLDLE--FTPGVKEVAKP-------------TLLQEINGIGPVGGNTT MLAEKIRPTAESTNLLMSKSPFIRTKTSWFHVFPEGFVLQLQEPHQNSMRYFKWGISRLI LESTRTPVVVPIFTYGFEKVAPEDSADKGINRWLPSNIGAEIHINIGDPIP-DETLESYR KKWRDLCNKYIDPKNP--------------------------TDLSEELKTGKMAKRLRS DLAAELREAVLAIRNSLGVFKPEDPRFKNPVFWEEYTRTEGKSDPDVRFIGKNWAIKRLQ KHLP------EYSEDE--P------------------------------- >Meyerozymaguilliermondii_YPR140W_EDK38432 -----------------------------------MSFPDVLRRGDDF-LKEMPRSS-TF WNYASHATCLMMISGTKIALN-TLYKPYLHGVE------------------K-LDEALER ARRENRSLLTVMNHM-------------------------------SVVDDPTFYAALP- WRFHT-------DIDTIRWGFGAHNICFSNTALSWFFNLGKILGTKRFG----FGPFQPS LDAAIRIMSPDDTLDLE--FSPLVKDVEKP-------------LLIQRASS-PSWKESSD -LVAHKK---SGANILMSSSPFIRKKTSWFHVFPEGFVLQLEFPHENSMRYFKWGVSRLI LEATASPIVVPIFSYGFEKIAPEDSADKGINRWLPSNVGSEVHIHIGDALP-DEQIEEYR EQWRRLCAKYIDPKHP--------------------------EDLNDELRNGSKVLELRS RIAADLREAVAGIRTQVGKFREEDPRFKDPEFWKRYTLTEGASDPDVKFIGKNWAIKRLQ KHLP------EFSED----------------------------------- >Komagataellapastoris_YPR140W_XP_002493075 -----------------------------------MSFPAVLERGDDF-LSEYPRRS-KA WAFISHAACVLVVGGSKLVLN-IAYRPEVTGLE------------------K-LDAALER SKRENRGIITVMNHM-------------------------------SVVDDPFLWGCLP- WKYFR-------DVDVIRWGLAASNVCFKGTFLSYFFSAGKILSTERFG----RGPFQPS LDATVRLLSPDDTMDPG--FMFVPSPKASLLHWIKSPLTQKIKEIDSK------------ ----------------PYHPPVMRHCPSWIHVFPEGFVCQLQPPHSNSMRYFRWGASRLV LEPTVPPIVVPIFSTGFEMIQPESGAENIFERYLPQNYGQEIKVVIGDPVD-DKVIEDFR KEWKNLCEKEYDRNNP--------------------------RDLSHELKFGKQAKDLRS RVAAELRQNVLNIRNQL-GFNPEDPRLKDPKFWKRYTNSKGLSDPDIKFIGKNWAVKEYQ AKVK------SYDEFG--NEIKDDQ---------------------R--- >Ogattaeapolymorpha_YPR140W_ESX03647 -----------------------------------MSFYDVLQRGDEFILKDRPGQS-RI WNFFSQATCMAVVGGSKAILG-LFYNVNVKGLD------------------N-LDHGLAK ARAENRGFLTLMNHM-------------------------------SVCDDPFIWACLP- WRYFL-------SLDDIRWGLAASNICFNSKASSTFFSLGKLFACERFG----RGPFQGG LDALVRILSPDDTLDTD--HIFQGTEKSIP---VGSTLATDVRSFYSP------------ ----------------RYTPPVLRYKTSWVHIFPEGYVCQLKPPHNNSMRFFRWGTARLI LEPTVAPVVVPIFTDGFEKIVPEAKVDDVVDSVLPQGIGSTITVNIGKALD-DRIIEAFR AEWRALCDKYHDKLHP--------------------------NDLSFELKFGKEAEALRS RVCDYLREKVAQLRLEN-GFPPEDERLKSQKFWSEYTKTDGASAPDIQFVGYNWAVRAYQ KNTK------TYDEYG--NEISK--------------------------- >Geotrichumcandidum_YPR140W_GECA09s04069g -----------------------------------MSLPAVQARGKAF-LSLNGLRSRPY WPLLSRATILATGTFAKLVMT-LPLKYKTTGFE------------------ENFLRTFDQ CKQQSKGFLTIMNHS-------------------------------SLLDDPFAWGVLPW WKFYV-------RGGNIRWGLGADNVCFGTPFLRFFFSLGQVLSTTRFG----GGPFQGS IDAAIHLLSKD------------------------------------------------- ------------------HQEYPKQRSNWVHIFPEAFVHQVYPPHENSLRYFHWGVSRLI LEADECPAVLPIFSHGFDKVIPEDRPDDY---RLWKQIGTTIHFGYGKAID-EKLLAEFR EKWRALVEKEQQGHTEP------------------------LTDLTDNLKFGPEAQKLRS DLARYLRDQLGAVRETM-GFPPQNPEFAEPEFWK----PEGGCK-DVPVMG---IVNKLP HHK----------------------------------------------- >Yarrowialipolytica_YPR140W_YALI0C14036g -----------------------------------MSFRNVSLRGSQL-LGKLDSRG-WG WYVAKKWNIGLVYTMCKVFLR--CKKVDIKGLD------------------N-LLEAHRQ ARLEGRGLLTVMNHT-------------------------------SVLDDPVVWGMLP- NDNGW-------IPYLMRWATGAKDICYKNKLYSLFFGAGQVLPITRFG---IGGPFQPG MDMCVRLLNPNNKIKYSAKYTPYLV----------------------------------- -------------HTNATSYPFWR-ESNWVHFFPEGYVHQALEPHEGTMRYFRWGTSRAV LEPVTPPIIVPMFSHGLQKVFQEIPKGYEMEGN-NTNKDRTISIRIGEPIS-ETTVAGFR NEWINLCHKENVGLNA--------------------------ETMPDVLKNGQEAKDLRS KVAAYLREEVEKLRLTVPNMNPELPEFKEPEFWSDIDKVHKG------VYNHRGKVRMLR NPTKGLIEVVEANKD----------------------------------- >Neurosporacrassa_YPR140W_XP_958270 -----------------------------------MASPQQQQQQQIQNHAQAPHSPNLP SRIASVMIMGLTGVISRTFLY-GFNDIEVKGLDRFK---------------Q-LLDSRED PERRERGLLTVSNHI-------------------------------SVLDDPVVWGVLP- LSYAF-------NPNNLRWTLAAHDICFANPTFSAFFTAGQVLPCHRLKHSAHGGLFQPS LTQAIRLLSSQPFTQPG--FSPAPL--TSP---VTSLSTPSAVDIPDPFTI--------- ---GTLTYSTTGSDSHPAPSIYTRNRHSWVHVFPEGLVHQ---HPQVDLRYFKWGVARLI LESEPAPDVVPMFIDGTQHVMNEERG---FPRFLPR-IGKKIRVAFGEVVDYEREFGDLR RRWRREVERVRQQEEEEV---KAAKGNELVAVENSSSKPRLLGDLPEQLKYSEEAQKIRI ECARRMREQVLKVRRELGGYDESDPNFGEASTWA----------PDRKVKAEKYKSR--- ------VDGSEINQD----------------------------------- >Aspergillusfumigatus_YPR140W_XP_755729 -----------------------------------MS------RSTDR-SATGDCPS-LP WRALSATTIFGVAALCRSFLY-MCSRPEINGLESFL---------------E-LLESRQD VSRRTRGLLTGIDPLYSTEFPCFCLIAWRTSIADMGLIRQYRTILACTMDDPIMWGAIP- LRWNFGL-----SSSNKRWGFGSHDICYQSRPLALFFTMGQVLPTHRLAHSPHGGLAQPA VTQAIRLLSKGP-------FPPDPH--LPP---PERQHWSLENICVDPFSD--------- ---LPTAYTTTGIDSHLAPSAYACNSYSWVHIFPEGKIHQ---APNKTMRYFKWGVARLI LEANECPDIVPIWLEGFDQVMHESRG---FPRFLPR-VGKDISITFGKKVDSEAVFGDMR RRWREIKAKAEVASPE--------------------SRNLPLGVLSDELLHDEEAIELRK EVTQKVRDLVLEVRRTR-GLSDEDPKHGLAETWI-----EEGPQREGKMKDESWSFQSRV QPCSLL----QLRRGG------------------------IIRG------ >Cryptococcusneoformans_YPR140W_XP_777272 -----------------------------------MSSPSL------------------- ---ASALTLSTIGLASRSFLRLTTKEFKIEGLPILLDALNIPHGEKGKGKIK-TDDGSDP SLKPRRGILTICNHN-------------------------------SVVDDPMMWSLLP- LSTYFPFTSPSHTCRNNRWTLGASDIMFTNSVHSKFFNLGQVIETHR-G----AGIFQEA IDRAVKLLQ--------------------------------------------------- -------------------------EGNWIHIFPEGKVNQQLTNPEGGLLRFKWGVGRII MDSEIMPEIIPMWISGFDQIMPETRG---FPRFVPR-PGAHISITVGQPLT--SQIQPLV KTWKDMASKEKGTLGIGGEWEQKVKGEGLAGQQQRE------VRDKGQLIHGRE-KEVRI KIVEALQEGMRKLGHDV---ERREGRFERG-LWSHSTRQSV------------------- -------------------------------------------------- MAFFT LOA1 >Saccharomycescerevisiae_YPR139C MEKYTNWRDNGTGIAPFLPNTIRKP---------SKVMTACLLGILGVKTIIMLPLIMLY LL-------------------TGQNNLLGLILKFTF--SW-KEEITV-----------QG IK-KRDVRK--SKHYPQKGKLYICNCTSPLDAFSVVLLA-----------QGPVTLLVP- ---SNDIVYK------------------------VSIREFINFIL-A---------GGL- -DIKLYGHE-----VAEL-SQLGNTVNFMFAEGTSCNGKSVLPFSITG-KKLKEFIDP-S ITTMNPA----MAKTKKFELQTIQIKTN------KTAITTL-PIS---NMEYLSRFLNK- ----GINVKCKIN-EPQVL-----------------------SD--N------------- ------------LEELRVALNGGDKYKLVSRKLDVESKRNFVKEYISDQRKKRK-- >Saccharomycesparadoxus_YPR139C_Spar_16.506 MEKYTNWRDNGTGIAPFLPNTIRKP---------SRVMTACLLSILGVKTIIMLPLILIY LL-------------------TGQNNLLGLILKFLF--NW-KEEITV-----------QG IK-KRDMKK--SKHYPQKGKLYICNCTSPLDAFSVVLLA-----------QGPVSLLVP- ---SNDIVYK------------------------VSITEFIKFIL-S---------GGL- -DIKLYGYE-----VAEL-SQLGNTVNFMFAEGTSCNGKSVLPFNITG-RKLEQFIDP-S VATMNPI----MVKSKKFELQTIQIKTN------KTAITTL-PIS---NMEYLSRFLSK- ----GVHVKCKIN-EPQVL-----------------------SD--N------------- ------------LEELRVALNGGDKYKLVSRKLDVESKRNFVKEYTSDQRKKRN-- >Saccharomycesmikatae_YPR139C_Smik_16.386 MEKYTNWRDNGTGIAPFLPNTIIKP---------SRMMTACSLVILILKTIIMLPLIIFY LS-------------------TGQNSILGLILKFMF--SW-KEEVSV-----------QG TK-KRDVKK--SKDYPQKGKLYICNCSSPLDAFSAVLLA-----------QGPVSLLVP- ---CNDIIYK------------------------VSIKEFIKFIL-D---------GGL- -DIKLYGHE-----IAEL-SQLSNTVNFMFAEGTSCNGKSVLPFSITG-KKLKQFIDP-S LATMNPV----MAQSRKFELQTIQIKTN------KTAITTL-PIS---SMEYLSRLLNK- ----GIHVKCKIN-EQQVI-----------------------SD--D------------- ------------LQELRIALNGGDRYKLVSRKLNVEAKKNFVKQFSNDQRKKRD-- >Saccharomycesbayanus_YPR139C_Sbay_16.467 MEKYTTWRDNGTGIAPFLPNTVRKP---------SSIATACSIVVLAVKAVVALPLILLY SF-------------------TKQNVLLGLILKLVF--SW-KEEVSV-----------QG IK-KRDVEK--SKHYPQKGKLYICNCTSPLEALSAVLLA-----------QGPVSLLVP- ---SNDIVYK------------------------VSVKGFFDFIL-A---------GGL- -DIKLYGHE-----VAGL-DQLSNTVNFMFAEGTSCNGKSVLPFSISG-RKLKEFIDP-S LATMTPA----MAKDKKLELQTIQIKIN------KTAITTL-PIS---NTEYLSRLLNK- ----GVHVKCKIN-EPQVV-----------------------SN--D------------- ------------LEELRIALNGGDKYKLVSRKLDVESKRKFVKEFTTDQRKKRT-- >Saccharomyceskudriavzevii_YPR139C_Skud16.433 MEKYTNWRDNGTGIAPFLPNTIRKP---------NSAMAACSMVLMVIKIIIMLPLIILY SL-------------------TNQNGLLALILKFVF--SW-KEEVTV-----------QG IK-KRDVEK--SKHYPQKGKLYICNCTSPLDALSVLLLA-----------QGPVSLLVP- ---SNDVVYK------------------------VSVKNFIDFVL-A---------GGL- -DIKVYGHE-----IAEL-SQLGDTVNFMFAEGTSCNGKTVLPFGISG-KKLKQFVDP-S MATMSPA----MAKSIKFELQTIQVRTN------KTAITTL-PIS---NMEYLSRLLNK- ----GVHVKCKIN-EPQVI-----------------------SD--D------------- ------------LEELRITLNGGDKYKLVSRKLDVESKRKFVKEFTTDQRKKKN-- >Saccharomycesarboricola_YPR139C_EJS41280 MEKYTNWRDNGTGIAPFLPNTIRKP---------SSLMTAYSMFILTVKAVVVLPLIIVY IL-------------------TNNNGLLGLILKFTF--SW-KEEVSI-----------QG VK-KRDVNK--SKHYPLKGKLYICNCTSPLDALTTALLA-----------QGPVSLLVP- ---SNDIVYS------------------------VSVRKFVDFIL-S---------GGL- -DIKLYGHK-----ITEL-SKLSSTVNFMFAEGTSSNGKSILPFSITG-KKLKEFIDP-S LATMNPA----MAKNKKIELQTIQIRTN------KTAITTL-PIS---NMEYLSRLLNK- ----GVHVKCKIN-EPQVV-----------------------SD--D------------- ------------LEEMRIALNGGDKYKLVSRKLDIQSKKQFVKEFTSDQRKKKN-- >Zygosaccharomycesrouxii_YPR139C_ZYRO0B04334g MEKYTSWRDKGTGIAPFLPPPVSNP---------GFGTLLLQTLLFAVKLVILLPLLITY GV-------------------SNSKSVLGWILGFLF--GW-KLDVTV-----------QG VK-RRDLGN--LRNYPQKGKLYLCNSTSALDALALDMIS-----------QGPSCFLVP- ---QDHTIFK------------------------MNKNQYFEFAQ-T---------GSL- -DASRFGHE-----VGNI-RQLKNTVNFMFLEGTCSNGKSVLPFALNE-TELLEFLQL-- -----------PETDRSATLQSIQLKIN------GSLVTPL-KVN---KFKYLVTMYTR- ----GVHFKIKLN-EPQKL----------------------V----P------------- ------------LEGLRASLNDNNKFKLVSRTLNVESKRRFVQEYSSKSSYRR--- >Naumovozymacastellii_YPR139C_XP_003677182 MEKFTDWRDKGTGIAPFFPPPTSSKEG-------KVLNSVVYGFFFMIKIILLLPFIIVN QL-------------------TGSKMALTTILKRLF--GW-SMDVNV-----------IG VK-RKAVTK--KEHYPTAGNLYLVNYQSALDAITLNLLS-----------QGNPIFLVP- ---DNVHIYK------------------------LSLWNFIRYTLDD---------GSL- -NISKYGEI-----VANI-NELKKSVNFLFIEGTCSNGKSTLPFNLNS-QTLLEFLEPDN NGTVKP----------QISLQTITLKVN------GPLATPL-PVS---KGTYLMRMLTH- ----HVRYKCKIN-EPQPL-----------------------TK--T------------- ------------LDELRIALNDGDKFKLVSKTLGIDSKRKFISEYSKTRR------ >Vanderwaltozymapolyspora_YPR139C_XP_001644118 MEKFTDWRDKGTGIAPFLPPTIKGP---------GIGLQIVYTLYIALSCILLSPVILLY SI-------------------SGNSSLLLVILKVLV--GW-KADIVI-----------QD VK-RKDIQP--AKHYPMKGSIYFCNLSSPLDAILLSLIA-----------QNDLIFLIP- ---DGSVLYK------------------------MNLQQLINFIM-D---------GSL- -SPKKFGQE-----FSQY-AQLKNYVTYLFPEGTCSNGKTVLPFNMKQ-DTLDELIEV-- -------------SSSSLKIKTIYLKGN------NTLVTPLGSSS---KFAYLIKACWK- ----SVTMKCKIN-NDDVK----------------------P----S------------- ------------LDSIRITINDGDKYKLVSKNLNIESKKKFTQEFKSYRN------ >Candidaglabrata_YPR139C_CAGL0D04950g MEKFSNWRDKGTGIAPFLPPPVPAS---------SKVSVVLNVAWYSVKMVLLLPIMALV MV-------------------TGDKFWHRFIYRVLY--GL-REEIVV-----------VG VK-KREVVP--WKHYPLRNNVYVCNSSSPWDVLLLGLIA-----------EGPAMFLVP- ---NAGTLYR------------------------MNADQYYSYAL-A---------GSL- -DAKLFGKE-----ITSF-NDCKGYVCFMFLEGTCSNGKSVLPFEITS-KQLGEFLYG-K DENDVPV-------KERINIFTVQLRLN------SSIVTPL-AIG---RREFFLRSIIK- ----GVKAKIKIS-HEPYS-----------------------AK--N------------- ------------LDSIRAKLMDDDKYKLVSKSLGIEAKRKFVSEFNKKHKL----- >Lachanceathermotolerans_YPR139C_KLTH0F14454g MEKFTNWRDKGTGIAPFIPTPPPLAQE-------KGLKGFLGGISFVLKLVLASPIVLVA LLLK---------------WTPAYHPLCKVAIKMIF--GW-NLQVSV-----------QG VK-SRKQG---PQFMPSKGKVYIVNYTSPLDPLVLWFIA-----------RGPVAFCVPK PQRKTASLYR------------------------LNFWEIVQFTL-G---------GSTW GSAQHDFQE-----IKSA-MELSNYVTYVFAEGTTSNGKSVLPFVVTQ-QFWNEFLGEPA VGSSSSVKTLTSTASRDAEVRAIHIKIN------SSLTTPL-RIG---AWRYLARASSQ- ----GVTYKCRIS-EPLGR---------------------------D------------- ------------LEKTRVALCGGDKFKLVGKELNTESKMKFAVEYGSRRR------ >Kazachstaniaafricana_YPR139C_XP_003956088 MEKFTNWRDKGTGIGPFLPPRSPKGG--------SIMMDYVFIVYGIIKSVLLLPLVLGN LV-------------------VDSIYMWEIILSVLFGSGC-KIDLMV-----------DG RKLKRQNEQ--KGNILSKGVIYMVNFTSIIDAMILKMICG----------GQNFRILVPN ---ENGKFFQ------------------------LGLIGLVKFTK-N---------GSL- -DVERYGNE-----ISNIEKELDKYIWFMFPEGTTSNGKSVLPFVVTS-ANLNEVIYG-- -----------DDEMKPVKVSSIRIKVN------QSLTTPL-RVS---LWSLIKNLFTK- ----KISVKCNVH-KVVIL----------------------DRDGVS------------- ------------LDTIRVQLNGEDSFKLVSKSLNIDSKRRFVEEYFRK-------- >Kluyveromyceslactis_YPR139C_KLLA0B11000g MEKYSSWRDEGTGIPPFLPERGLPSAN---------------LLHLVVRWLQYVIISLAS IIL-----VPF----------LGLDSVYQLRMLSLY--KI-ETDVQV-----------DG VK-KRQICK--EKHFPKPGCLYVANALSPFDALALRSLVD---------KKNECNFIVP- ---REDSLYT------------------------IQLEDWYQFAL-D---------GALG TRIDNRLVE-----IKDLETVCNGKVNFLFAEGTTSNGKSVLPFEVQP-KLLQDLIDV-- --------C-------GSKVKSISLKLH------AKITTPLKPKS---AFKYKLGCMSQ- ----GVRYKVRIS-EDVDR----------------------P----D------------- ------------VRKLRINLVGGDEYKLVGKKLDFRSKLRFSQVYYS--------- >Eremotheciumgossypii_YPR139C_NP_986921 MEKYSEWMDKGTGIKPFIPVSATNRSN-------------VALGIWILKAVLLLPLVLIW AVLR---------------AVGLGTPLGRWLLQLLV--GF-EYQVSV-----------DG VK-KRDLS---TRHLPQRGRVYLANFASPLDGLAAAVVS-----------AVPVLLLVP- ---RGDTLYQ------------------------FSPWQLGWFAL-S---------GAL- -DIPAGQPK-----LDAAAAASSGCALFVFAEGTTSAGRGILPFELGD-PVLAQL----- -------------SHDADGIYTASFRLSQ-----SDLATPV-PTG---LWAYLGRLATR- ----GVQYHCRIQ-GPFSK----------------------G----T------------- ------------TSELRQALAKGEGFMLLGKNLDLKAKRGFLQTWQPSTGR----- >Candidaalbicans_YPR139C_XP_713693 MEKFSSWRDKGTGISPFMPQKLPTFQKNN-----SLLSVASKSPIFLIKLPFFIITYLIY TI-------------------TGFTFILKFILTILF--GFNRIDFGV-----------DG IK-KSQIDK-LTSYKPKKGDLIVTNYITPLDGYFLFLLSGTFSSSSSSSSSSQIVILIPN ---ESGDLYQ------------------------YSPLGLINHSF-T------YSNSNS- -NFSSSGKL-----VEDV-SKLQNKIVFLFLEGTLSNNKSILPFIKLN-SKYS------- --------------FDDFNIKSLVVKLIP-----NYFTLPI-PHVS--KLQYFFELLTNL SQK-SVRYKMYKF------------------------------DEFD------------- ------------IAKIRNSF-ELNSLTSMSQDLNIDSKNKFIDYYFDHSIKKN--- >Millerozymafarinosa_YPR139C_PISO0N22607g MEKFSQWRDKGTGISPFMPEPKPS----------NPFFTAVKAVVFVFKFPVFVLLLGAY WV-------------------SSSAFILSIALKLFM--GFSRFEVSV-----------EG LK-KSNTAG-INQERPKINELIISNYVSPLDGFIFATISQ--------LRWSKIVILIPD ---EEGETSM------------------------LSVWSLFFHAL-N---------IPG- -KDAKSSQK-----LKNL-SSLKGMAVLYLPEGTPSNNRAILPFYKLK-NFAG------- --------------ASDFVVKTLVLKLKP-----RYLTTPL-PTTS--SLGYLFNLLTNF DKNTSIIAKIYCH-DPSKK-----------------------DKEPD------------- ------------LDRAKYCF-QVSQLHSVSDDLRISSKLKFFDYYSTYDNDKPKKD >Millerozymafarinosagi_YPR139C_PISO0M22364g MEKFSQWRDKGTGISPFMPEPRPS----------NPFFTAVKAVVFVFKLPVFILLLGAY WV-------------------SSSAFILSIALKLFM--GFGRFEVSV-----------EG LK-KSNTAG-INQKKPKINELIISNYVSPLDGFIFAAISE--------LRWSKIVILVPD ---EEGEASM------------------------LSVWSLFFHAL-N---------LPG- -KGAKSSQK-----LKNL-SFLKGKAVLCLPEGTPSNNRAILPFYKLK-NSAG------- --------------ASDFAVKTLVLKLKP-----RYLTTPL-PTTS--SFGYLFSLLTNF DKNSSIIAKIYCH-DPSKK-----------------------DKEPD------------- ------------LDHAKYCF-QVSQLHSVSDDLRISSKLKFFDYYSTYDNDKPKKD >Debaryomyceshansenii_YPR139C_DEHA0D17963g MEKFSNWRDKGTGISPFMPIPEPA----------MSFMIVPKAIVFLMKMPIFVLALGVY FL-------------------LPFPVIGRFIILVLF--GFRNYELTV-----------DG VK-KSKTDE-INATKPTVGDFVVVNYQSPIDGLILAALSN--------ANWNKIAILIPN ---KEGELYQ------------------------YSIWGLIRYTL-S---------TDI- -GVPTSTIK-----IGNY-SSLKEKLVFCFIEGTPSNNKSILPFMDSV-AAIP------- --------------KTAFNFKTLIVKIQP-----GYLTTPL-PIVS--KRRYFVRLLTNL SKNSSIRAKIFKH-APTES-----------------------KDTFD------------- ------------FRLSKHCF-EVGQLNLIGQDLNINQKITFYNYYIDHKVKKQ--- >Meyerozymaguilliermondii_YPR139C_EDK36520 MEKFSNWRDKGTGISPFMPVPVPRS------------SSSMASLVFLLRLPVVILTGLLY VV-------------------FPIQIVAKFITLVLL--GFNRYDLSV-----------EG VR-RSKLDE-IDRSRPSVGDFVVTNYTSPLDGFFLAGLSN--------TFWYKIVLLVPD ---EKGELYE------------------------YSIWSFFWLTL-S---------RDI- -GVSRSNIK------ADY-SKYTNKLVFLFAEGTPSNNKALLSFVPNI-PPVPA------ --------------KLRFKFKTIALRIFP-----PYLTTPI-PVVS--PFSYLYQVISHY DHNSYIRAKIINH-DRSLY-----------------------GDRYN------------- ------------IDEASASF-ELAQLNVISKDLDIQEKRKFYSYFVDYQVSK---- >Komagataellapastoris_YPR139C_XP_002491337 MEKYTTYRDKGTGISPFLPLNKPKV---------NIFLRLVGVVLGVLKLLVLLIVGLLY PV------VPL---------------LSTKAVLFLL--NV-DVDVSV-----------DN IK-KANKPL-IQLNLPQKGDFVISNYQSPLDPLVLSLITN--------NRLKNIVWLIPD ---IEGNLYE------------------------YSLFGVVVHAL-S--------SPNL- -HAQKNGKK-----IQLS-SISESKTVFLFPEGTTSNNKSILPFLVTT-DTVSV------ -----------PKLFKKFKVKALSIKNEN-----PYTTTPI-PQA---LASYLLTNLFTR N---SSHYRLK---EFILD-----------------------KDH-T------------- ------------WPEIRDLLSNSGRLKLVGKDLSLEKKVEFIEKFR---------- >Yarrowialipolytica_YPR139C_YALI0C14014g MEKFSQYRDKGTGVAPYLPHPRSKADGSLPSTIFVVLQAPLALVESVIKIPLLLALLALY AGI-----IQFITIE------PVRKAYFSTLLFVS---GFWFWNVSA-----------EA VR-RNKL----TEAYPKPGEVVVSNYLSPIDAFVYSALF-------------DPVFIVPH ---ASSRVYQE-----------------------LGPFGVFFKAL-G--------IPEI- -VPPTHGES--LSKIVFD-ATSKGRAVVVFAEGTTSNGRGLLPLLHIDFHQLSQ------ ----------------NTKVIPAGLRLAP-----QYITTPL-PVT---LPMWVFRLLSNP T---GWHVSLRFA-EPCYA-----------------------KDTNV------------- ------------NNTLVESICRVGRLKSIGPDLGVEGKRNFWKVYNKKKDV----- >Geotrichumcandidum_YPR139C_GECA02s07787g MEKFSNWRDKATGVAPFLQISNQT----------NVLKAALTVVSVVVRVPLLLILTHFL VILP-----------------NAPQFVLSSILYVL---GVFSWDVQV-----------TG VK-KKSYSD-TKPFLPKAGSLIYTNFISPLDPIVYASLF-------------KCIFAAPH P--SNGQIIE------------------------YNLFSIIKYAL-S--------IQDI- -APPVDSKKVSLDILAKR-ARSTGSVIIFFGEGTTSNGRGLLTTPSIN-SPLTS------ ----------------DLTVVPAGLRYGP-----QYLATPL-PRY---FLGWLWTVLYGF Q---IWSVRLRFG-APIIT-----------------------RDVDSS------------ ------------IDEITSSLCQIGRLKKLGSDLDIHAKREFLKAQNNYK------- >Aspergillusfumigatus_YPR139C_XP_755755 MEKFSQFRDRGSGIAPFLPIPSQP----------LGWKLPLGIFLFCFRLPLLIFVCLSY FLL-----LQWLPIGS-----LGKKASLWCILGVP---SIWWIDLQV-----------DG VR-KGSLSKQHQARLPGPGSVIAASFTSPIDPLYLAAIF-------------DPVFTASY P--NSRRVEH------------------------ISLFQAILRAF-A--------APQV- -RPPPGARL---VDVASLLEKYPGRPIVTFPECTTTNARGVLPLSYSL-LGVPA------ ----------------GTKIFPISLRYTP-----GDVVTPL-PGS---YLSFLWKLLSRP ----THCIRVRIA-ECVVR--GAASAADKAGASKLARQPSYDTNYFD-----TLEQSDGG ---ALAPGDKALLDQVGDALARLGRVKRVG--LAVKEKQDFLRSWTKTRRT----W >Neurosporacrassa_YPR139C_XP_958281 MEKFSQFRDRGSGISPFMPSPAPTP---------SLLSTLSGPLIFLLRLPFFVLYTISY FLL-----LPLLP--S-----PLRKLLLWGFFALT---GTWWSDLQL-----------DG VK-RGSLSQQPPSRIPRGGTVIAANFTSPLDAVYLAAVW-------------DCVFVQSF P--GSRQVRR------------------------LSLWQAISLAL-S--------PRQL- -AGPPAGDSEKLTTIAQLLKDYPTRAIAVFPECATTNGKGILPLSPSL-LTVPS------ ----------------STQIFPLSLRYTP-----VDDTTPV-PGGVKVWLSFLWKLLARP ----THCIRIRIG-EGLVNTVGASNGVSHGESSGV-----------D-----VRERQEGG -DGELTAEEQRLLDKVAETLARLGRAKRVG--LTVEDKKNFVKAWEKRRR------ >Schizosaccharomycespombe_YPR139C_NP_593657 MEKFTRWRDPGTGIAPFHPINTETPSG-------FNFKWILIVVVMILRVPLCIISVTLW FLWSCFL-KPILSIQPKL-SFFIDSSLSRLLLLCF---GC------------------LK LS-KSTSGSFVQGDSLQPGDILAVNHSSPLDVLVLSCLY-------------NCTFAVCD S--KTSNVSI------------------------ISAQAYFWSCFFS--------PSKL- -KITDAKPL---AKVAAK-ASKIGTVVILFPEGVCTNGRALCQFTPCF-DSAKE------ ----------------TDRIFPLYIKYLP-----PCVTLPV-PS----LLSFARSVLLTV ----SFEIRIRFSAEPLIP-----------------------RNCTD-----V------- ------------TESAQEVLSKLGRSRVV--KLGKSDKLSYLDARSKKHV------ >Cryptococcusneoformans_YPR139C_XP_773987 MEKYSNWRDPATGIQPFLPPVSPRSGSS----LFVAFLAPLCVVHSLVRGVLLAVLGTLH VLFVDWLCLLFVPIPPLYRAVNGCLTALTCRLALAL-MGYWWISTEMVSPRRGDGWTDSG VDRKTGVSQ-ISKRAPRRGDLILANWTSYVEVLYLAFRH-------------NPTFLLPV ---YSNDIFQELPKTGRHTGTGSAAINTPTAVVQPPFLGYLPYTLTSLLARTGLPPAQC- -DVPPNGVY---KTLREA-RRKEKRPVVLFPEGTTGNGRAILKFGEGI-LAEGD------ -----------VGGDDEGIVWVKFFRHSPPTAFSPSATCPL-PTP---LKHLFFSQLYTP TPYSRRSLHIRTL-HPAAS-----------------------PSSPSFLPGEILNNQPGG LDAAGKDHKSVWREACAVVLAEVGKVRRV-KGMGWAEKKAFLEYWARGGRR----- MAFFT MUM3 >Saccharomycescerevisiae_YOR298W M-------GFVDFFETYMVGSRVQFKQLDISDWLSLTPRLLILFGYFYLHSFFTAINQFL QFINTNSFCLRLHLLYDRFWSHVPIIGEYKIRLLSRALTYSKLKIIPTLDKVLEAIEIWF QLHLVEMTF-EKKKNVQIFITEGSDDLNFFK-DSKFQTTLMICNHRSVNDYTLINYLFLK SCP--TKFYTKWEFLQKLRKGEDLAEWPQLKFLGWGKMFNFPRLDLLKNIFFKDETLALS SNE----LRDILERQNNQAITIFPEVNIMSLELSIIQRKLHQD-FPFVINFYNLLYPRFK NFTTLMAAFSSIKNIKRKKNRNNIIKEARYLFHRELDKLVHKSMKMESSKVSDKTTP--- ---PMIVDNSYLL----------------------TKKEEISSGKPKVVRINPYIYDVTI IYYRVKYT---------DSGHDHTNGDLRLHKG--YQLEQI--SPTIFEMIQPEMES--- -ENNIKDKDPIVVMVNVKKHQIQPLLAYNDESLEKWLENRWIEKDRLIESLQKNIKIETK ------------------------------ >Saccharomycesparadoxus_YOR298W_Spar_15.506 M-------GFVDFFETYMVGSRVQFKQLDISDWLSLTPRLLILFGYFYIHSFFTAINQFL QFVNTNSFCLRLHLLYDRFWSHVPIIGEYKIRLLSRALTYTKVKIIPTLDKALEVIEIWF QLHLVEMTF-EKKKNIQIFISEGSDDLNFFK-DNKFQTTLIICNHRSVNDYTLINYLFFK SCP--TKCYTKWEFIQKLRKGEDLPEWPQLKFLGWGKMFNFPRLDLLKNIFLKDETLTLL PDK----LRNILETQNNQAITIFPEVNIMSLELSIIQRKLHQD-FPFVINFYNLLYPRFR NFTSLMAAFSSIKNIKRKKNHNNIIKEARHLLHREIDKLVHKSITIESSKVSDKITP--- ---PMIVDNSYLL----------------------KKKEEISSVKPKIVRINPYIYDFTV IYYRVKYT---------DSGHDHINGDLKLHKG--YQLEQI--SPTIFEMIQPEMES--- -EKSIKDKDPIVVMVNIKKHQIQPLLAYNDESLEKWLENRWIEKDRLIESLQKNIKIETK ------------------------------ >Saccharomycesmikatae_YOR298W_Smik_15.479 M-------GFVDFFETYMVGSRVQFKQLDISDWLSLTPRLLTLFGYFFIHSFFTSISVFL QFVNTSSFCLRLHLLYDRFWSNVPIIGEYKIRLLSRILRYTEVKIIPNLDKALEVIEIWF QLHLVEMTF-EKKKKVQVFISSGSDDLNFFQ-DNKFQTTLMICNHRSVNDYTLINYLFFK SCP--TKFYNKWELIQKLRKGEDLPEWPQLKFLGWGKMFNFPQLDLLKNIFFKDETLTLS PEN----LKDLLVAQNNKAIAIFPEVNIMSLELSIIQRKLNQD-FPFVINFYNLLYPRFK NFTSLMTAFSSIKNIKRKKNHNNIIKEARYLFHREIDKLVHKSITMEPSNMSDKILP--- ---PLIMDNTFLL----------------------DKKKNTSNDKPKPVRINPYIYDFTI VYYRVKYT---------DSGHDHINGDLKIHKG--YELEQI--SPTVFEMIQPEMES--- -EDNRKEKDPIVVMIHIKKHQIQPLLAYNDESLEKWLENRWIEKDRLIESLQKNIKVETK ------------------------------ >Saccharomyceskudriavzevii_YOR298W_Skud15.465 -----------------MIGPRIQVKQLDISDWLSLTPKLLILFGYFYIHSIFTAISQFL QFVNRNAFCLRLHLLYDRLWSHVPIIGEYKIRLLSRVLNYSEVNVVPNLDKALEVIEIWF QLHLVEMTF-EKKKNVQIFISSGSDDLNFFK-DNQFQTTLMMCNHRSVNDYTLINYLFFK SCP--TKYYNKLEFIQKLWKGEDLPEWPQLKFLGWGKMFNFPQLDLLKNIFFKDETLTLS PDK----LRNILKHKTIKL----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >Saccharomycesbayanus_YOR298W_Sbay_8.347 M-------GFVDFFETYMIGSRVQVKQLDISDWLSLSPGLLILFGYFYIHTFLTAFKEFL RFVNRNSFCLRLRLLYDRFWSHFPVIGEYKIRLLSRILRYTEQKMIPNLEKILEMIEIWF QLHLVEMTF-EKKKNVQIFISSGSDDLNFFK-ENKFQTTLMMCNHRSVNDYTLLNYLFFK SCP--TKYYNKXXXXXXXXXXXXXXXXXXXXFLGWGKMFNFPQLDLLKNIFFKDETLNLP PDK----LRTILETQNNQAIAIFPEVNIMSLELSIIXRKLHQD-FPFVTNFYNLLYPRFK NFTSLMSAFSSIKNIKRKKNHNNIIKEARHLFHREIDKLVHKSITMEPSKMSNKIMP--- ---PMIVDNSYLF----------------------EKKEEASQGRPKPVLINPYIYDFTI IYYRVKYT---------DSGHDHINGDLKIHKG--YQLEQI--SPTIFEMIRPEMES--- -EDNSKEKDPIVVMVHIKKHQIQQLLAYNDESLERWLENRWIEKDRLIDSFEKKIKIETE ------------------------------ >Vanderwaltozymapolyspora_YOR298W_XP_001644271 M-------PLVDTIETFFVGQSSTFGEWTPKDWVYVGARILILLNYFIWDTVVYFEVKLL RLLCYGNFHRRAIEINGKIWDNVPILGNKARKVLPYILYFIDKYLLPFLERISNLIRLYY QYHIVEMTI-KNKKNLKIFVTGDSETLELFD-EGGQMTTLLLSNHRSLNDFALISYLVQN TH---IVKLNRRRFLNNLRM-IDKMNFPRVNFISWGKIFNSPDVSLLKSILINDENITIT NRN----IKEHLVKNGNQVLVLFPEVNILTTELSIVQRKLNQE-YTFVAKFYNVLYPRFK NFVETIACFANINNVKRQS-QNNIILEGKTFIHNKMEKFVTKI--SSSSKATDVVNEEVL KKNQVVLGLSTLLKTQLMKDSKDETLPFANDSENEGGEKEINSELLKHIKINKNLYDLTI IYYKPKYT---------DKAHDHVNGNLKLHEG--YQLEQI--DPSILEMLKPESKS--- -----SLLSPIVIMIHINRHDITELLPVRNHALEKWLEDQWRAKDKLIDSIDSGIKVT-- ------------------------------ >Zygosaccharomycesrouxii_YOR298W_ZYRO0C01034g M-------TIRDSIETHFVGPKLEIQNWSISDWVLVSKRILILGSYAVLHTIVKILQKLL QLLVNNPIIGFILVINGSLWRLVPIVGRYAGRILPKIISYVKETLIPSLGKFIQLIQLSF QLHIVQMTL-KNKKNIQIFITAESDDLELFDSEENLKTTLLLSNHRSINDYLLINYLVQS CSPNTAGHFRKRHLLKQFWE-RNQLPIPPLNFISWGKICNFPHISFVKNILTQDENTFVP PRK----IKEHLKANGNQILAIFPEVNIMTTELAIVQRKLNQD-YPFVTRFYNVLYPRFR NFISLIKCFANINHVKRRQ-HNTLFDHAKFFFENGMDKLIYKT--SAHGKQRDAGQEQA- -NAAMIVGLPNSL------DHVEMTLSDESPKQEPAEGFSNTDEQKESVSINPYLYDLTI VYYRPKYT---------STGHDHVHGRIKIHNG--YQLEQV--NPSLLEMLKPEGKSLSS SDANLSILPPIVVMVHIKKHELDPLLPTKGRNLEKWLEVQWYEKDKLIDSIENGIRIK-- ------------------------------ >Naumovozymacastellii_YOR298W_XP_003674537 MI---SLRGIIRFFQVHVVGRFQLTQGETLRELTTLTFKILTLCLCFFLHSLFSTVRSLI LFVSECSIIRRIQIYKKNFWSQVPIIGKSALRCLNYIDSFINVKVVLLLEKIISSIEIYS QLHVIEILF-KSNSNIQVFFTEDSERIDLHD-EDDQQTTLVISNHRSVNDYLLINYLLQD TLL--IKYTRKREVLNSFWN-NNKRMIPQINFVSWGKIYNFPRLSLMKNIALKDENTYCR EEE----LEEAIEKNGNQTFVLFPEVNILTTELGMVQRKLNQD-YIFVTKFYNVLYPRFK NFISTINCFANKMNIKKMK-HHMVINEAKQFLNERFEKIVNVS--YESIREKDAAQV--- ---SMFLGG------------------------NQRQSQSQNKKKKTSFKLNPNIYDLTI VYYKPNYT---------NIGHDHVNGNLNLHEG--YQLEQI--VPSFLDFLRTSIKSV-- ---NEENNEPIIIMINISKIKIAPLLPMTEKKLEKWLENRWGKKDKLINKFETNIKMK-- ------------------------------ >Kazachstaniaafricana_YOR298W_XP_003956927 M-------GITDFLKVHIAGSDFNLRCLSLDRKKNIVFEFSQLILYVVAYIIVSKFQYGM LFILNSKISRRVYRLYCKFWYYIPILGVINIGIANSISNFLFHVFPPFLNRISTVLEVLF YYEILQMTF-SKEGNIKIYFTNDSEELLIMN-SNQLLTTLIISNHRSVVDYILINVLLYR NFNGNWESMSRSDILKRAWN-ETLNIHPQAKFISWGDIFKLPTLYLLINILTKNENHVID SGN----IIRYLNTWGNQVFVLFPEVNILTTELGIIQRKINQNYYPHVMKYYNVLYPRYK MFVNVINAFAQLCDIKKSL-LNRKLIYPRHIISEATVRISNKV--DKILKEDDSI----- ---PLVFGNYESV---------------------GQQNELLINSKDQKIFLNKYLYDLSV VYYKAKVV---------EKSHDHVKGTLKPQKG--VQLEQI--VPSLFDIFFANYKR--- ------GRDPIIVIVDIRRHRIDQLLPLKNEKLEKWLEILWMKKERLIIENEAKISLK-- ------------------------------ >Candidaglabrata_YOR298W_CAGL0A03806g M-------GFVTFVESYVVGSSQDISTWWYTDWIVVGWKAAIIGAYLGIHTLLTMTRLVL QTIILTPLFLRCYSIYRRFWWHVPFFGPILLEAGSYCLTSIPRVINPTLSLICEIIEIIF QIHVTELMFGHEKESVRIVYGEDCAEVDLFDEENQLMTTLVLSNHRSLVDYLLIQHLLMK GAKQ-HTTLRKKDVIYNYFK-QRILKGMQVQFLSWGQIVKFPTLLFGFNVINSDENCFVP SDD----LETFLKS-TNQCMVHFPETNILTTELFLVQRSINSS-KTFAVKYNNLLNPRFK TFVNVIDCFAKCTEIPRLP-HIPIVTETKKFINKKLDDIITNS--NGDVQQNAVV----- ---THIIAHSDVK--------------------SNQESKPHKTKKQHRVRINSHIYDITI VYLRVKYV---------TNVHDHIDGSIVPRSG--YQLDEI--APSLLEFLRPDSKV--- ------DRDPIITYVNIKRFDTDAILCLKDRHLEKWLEDIWKQKDLEISKVIEKITVN-- ------------------------------ >Lachanceathermotolerans_YOR298W_KLTH0E04158g M-------SILDTLRTHFVGSGLQLRADNVPAALSLVLQLVLLVQYVAAYNVWSFKTWIV EQSVDSRPSKWAIGTVSKTLIWIPLVGERLTENLEHVVCSIKLRVLPPMKRVEERLELCY QVALADLTF--RHGNVRLLVTGDTEGFPTA--VTNKRSSLVIANHRSVMDYSLINYLAQG E----ERVAARQNFWRLFES-KETDTMLGLKFVTWGRVCNMPSLRLLSSILAGDENCAVD AAR----LQEFLEDRGNQILAVFPEVNVLTPELRLVQRKLAKD--NYLPMLNNVLYPRFK NFKAAIRCLSHVRGVGIAR-RGRRLRNAVTKADSMVCKIRHPG--------SRISDTQIA -QVSMFLGRVEDD----------EAL--------AKNKKKLKPTQRALLSVDPFVWDLTI VYYRAKIS------KGKDHAHLHEQEQKRLEDGAHYQLEQV--TPSFLQMASSSF----- ------QDSPLLIRIHTCKHPMSKLLALSDRKLEKWLERRWMQKDEMIDSIQKNVKIS-- ------------------------------ >Eremotheciumgossypii_YOR298W_NP_986071 M-------PFLSTIEANVTGAFSELSGMSPSAIAQLVLKTLTIALYMFVYGFWSTFAFVF DCTLRSDSVDQAITVGLRMITIVPVIGSPLGRRLSLLVKLLKTELLPFLDEMVRLTEYAF HVKMINDTI--CGDNVKIIVTGDPFSLDYV--EAAPLTSVIISNHRSVIDYAVISKLVLE TQ---ERIPNHNKFLMSTAKKRRFVHPPPFRFLTWAKITNFPTLSLFFNIWSKDENSIVS ATT----IHSHLMKHRNTTFVLFPEVNSITPELVMIQQKLLKSKYEDTPSLKQVLYPRYK QFNSLVKDLACWKKVKKRN--------------SIMEKVVDRL--DKWIHDDDLLDQDLI -ELESFLTA------------------------EEDAAATQRSSNVEQIRINEFMYNLTI VYYQPVLKCNDP-----DHIHEHNHAVGIKDPH--YQLEHI--TPSLWDMYRAQE----- ------ADQPIVIRVHIDRHRMDPLLQMKSRHVEKWLENYWCEKDKQIAVMDTAVKLK-- ------------------------------ >Kluyveromyceslactis_YOR298W_KLLA0F25058g M-------SVLSTLQTNVTGPWFSIQDKHLIK--------------CVAYSWFLFILFIL QSVLAG------WIWYMNQWSRI-------------ISSKYYYRGIMKTEKIQTMVNIWI NEFIIWSVL---REDIQIIYEGETI-------NTKCKNQLILSNHRSIIDYTLI------ ---------------------QSQFGAENVIFAGWTRLMKYPSFKHFWTIFRHDENDNVS VSK----IKKFY---GPENLVIFPEVNIFTPEVKLIERKLMKLKYKGLPVLHNVLYPRFG TFVNLIKAFSNSNDRKWCR---------------MLEYLILPT----------------- -----------------------EPI----------------------LRDSMKLLDLTL VYYKITLN---------SMGE--------------YKLEQT--IPALWDIWSLE------ --------SPMILCIHASYHDVDKLTKKKPKQLESWLETQWCAKDKLIDTFELNVEIV-- ------------------------------ >Candidaalbicans_YOR298W_XP_721724 M----------------------------------------------------------- ------------------------------------------------------------ ------------------SILGD--------------------------DY--------- ---------------SPMRQ-CEQFSLPIINFFSWFLVWRVPTVKILLHMLKSDENWELE SKSLSFVFSRLLRSKFSEWVVLFPEVNIWTPNGAALQGQVSNK--YFLPKFNHLLYPRFS AFFNIISILNQSKPHAYLN----------------------------------------- ------------------------------------------------------MYDITI LYTR--------------NGHGTISNQYK--------------PPTLLDIFASA------ --------EPITVIVYVKIRSVSR-IPTKRKKLEKYLEHLWIHKEKVISQLKAENDTHIQ LRISKDNFSV--AP---------------- >Millerozymafarinosa_YOR298Wa_PISO0B09131g MITDKG------------------------------------------------------ ------------------------------------------------------------ ----------QQLNNVKFEVKGD---------PITSDSAVVISNHQSLADHLVMPYLATN AVHSINDSTESEE--AKQAT-LNKIVLPRINFFSWFRVWNVPSIRVLLNMAKCDENWELD STLSELIFSRFLKTKVPEWIVLFPEVNIWTEEAAILQKAQSEK--FYLPVLKNVLYPRFS SFYNVISVFNNKENYKFVK----------------------------------------- ------------------------------------------------------LYDLTI LYKREQKK--------PRSLGGAIINALTPRLPEEPVETYF--QPSLLDIVFSD------ --------YPITVQVTVKTKFLNR-VPLKRNKTEKWLERLWLEKDKNISQALSSALKQEE -SIGQELTAVPLSPIKKIPVL--GPI---I >Millerozymafarinosa_YOR298Wb PISO0A09064g MITDKG------------------------------------------------------ ------------------------------------------------------------ ----------QQLNNVKFEVKGD---------PITSDSAVVISNHQSLADHLVMPYLATN AVHSINDSTESEE--AKQAT-LNKIVLPRINFFSWFRVWNVPSIRVLLNMAKCDENWELD STLSELIFSRFLKTKVPEWIVLFPEVNIWTEEAAILQKAQSEK--FYLPVLKNVLYPRFS SFYNVISVFNNKENYKFVK----------------------------------------- ------------------------------------------------------LYDLTI LYKREQKK--------PRSLGGAIINALTPRLPEEPVETYF--QPSLLDIVFSD------ --------YPITVQVTVKTKFLNR-VPLKRNKTEKWLERLWLEKDKNISQALSSALKQEE -SIGQELTAVPLSPIKKIPVL--GPI---I >Debaryomyceshansenii_YOR298W_DEHA0D18832g M----------------------------------------------------------- ------------------------------------------------------------ -------------NGVNFVVTGD---------DINTDSAIIISNHKSLVDFIAMAYLA-- --RYTNDMSNNEE---NEKS-FKNLTLPRINFFTWFKLWRIPSIRVLINLAKCDENWELE SSLSKIVFGKISKSKVPEWIVLFPEVNIWTEEDSSLQKAQGEK--FYLPTLQNILYPRFS AFYNVISTLNSKEHSKFNQ----------------------------------------- ------------------------------------------------------LYDVSV LYESKSIESKTPTNKASKDESNAVSSSETPQ---DKGVNLV--SPNLLEIFSSD------ --------NPITIHIHVKSKRLSR-VPTKRSKIEKWLENTWVEKDKFLDQWKTDLSKATT FSVNKGRTPQNSPPQIKTGVFRSGSIKSSI >Meyerozymaguilliermondii_YOR298W_EDK36552 M----------------------------------------------------------- ------------------------------------------------------------ ----------QKSSKFGIRVTGD---------KMDSESAIIISNHASLLDHVVLAHLA-- ----------------QHET-DETMAKPRVSFFTWFSLWTLPSTRAIRNMAKSDENWELS SNAGVHIFKSVLNSSVNDWIVIFPEVNIFNSESKSRQDYLGNK--YFLPKLQHLLYPRTQ SVFSLSSALSG--DYKFNK----------------------------------------- ------------------------------------------------------MYNVTI CYFARNED---------------------------STVSLI--NPTLLDLFAAK------ --------SETLVVVHVKQHLIKK-LKYKRPRLERWLEKVWLEKDAVVQASVDSKLTL-- -------------P---------G------ >Komagataellapastoris_YOR298W_XP_002494158 M----------------------------------------------------------- ------------------------------------------------------------ ----------LKLNCVKIEITGD---------ELEVDSAVLLSNHRSIADYIVISALA-- --QSLEDKG------------RPEIDLVSVKFFSWFSLWGLPNLNVFNNILSCDENWELD TSTTYNTFNPSVVSTKPEWISVFPEVNIWSAENNELLNELNEK--YYLPKLQNVLYPRFS STFNVINGLYK---SSFSK----------------------------------------- ------------------------------------------------------LYDITI LYYKKKAADPQKIVK--MSQTETAIQLESSGEPDEMVRTTLFDSPSLLQVLGEYP----- --------SSFVVRVHVKLKALPR-IPLKRKKLEKWLEKEWVEKDKLLEQLQTTILTNHL ---------------------------KEK