Supporting Information for Yasukochi and Satta, 2014
Files in this Data Supplement:
- Supporting Information - Figures S1-S10 and Tables S1-S3 (PDF, 302 KB)
- Figure S1 - Expected distribution of KB(m) values. (PDF, 155 KB)
- Figure S2 - The relationship of level of amino acid substitutions at the PBR (KB(m)) and coalescence time (m = KS) of alleles for 24 rat RT1-Db1 (HLA-DRB1 ortholog) alleles. (PDF, 149 KB)
- Figure S3 - Neighbor-joining (NJ) and maximum likelihood (ML) trees based on nucleotide and amino acid sequences in the non-PBRs of HLA-DRB1 alleles. (PDF, 168 KB)
- Figure S4 - Maximum likelihood tree with the HKY model based on nucleotide sequences (690 bp) in the non-PBRs of HLA-DRB1 alleles. (PDF, 164 KB)
- Figure S5 - The number of transition and transversion substitutions at the PBR in HLA-DRB1 alleles. (PDF, 129 KB)
- Figure S6 - The level of amino acid substitutions at the PBR (KB(m)) among HLA-DRB1 allele pairs that share the same coalescence time (m = KS + KN) in a Japanese population. (PDF, 151 KB)
- Figure S7 - The level of amino acid substitutions at the PBR (KB(m)) among HLA-DRB1 allele pairs that share the same coalescence time (m = KS + KN) in 45 non-recombinant alleles. (PDF, 151 KB)
- Figure S8 - The level of amino acid substitutions at the non-PBR (KN(m)) among HLA-DRB1 allele pairs that share the same coalescence time (m = KS). (PDF, 148 KB)
- Figure S9 - Relationships among KS, KN and KB. (PDF, 143 KB)
- Figure S10 - The mean number of nonsynonymous substitutions at the PBR (KB(m)) among HLA-DRB1 allele pairs that share the same KN and KS values. (PDF, 177 KB)
- Table S1 - The allelic pairs consisting of phase II in the HLA-DRB1 locus. (PDF, 137 KB)
- Table S2 - Parallel substitution sites in the PBR among allele pairs over all phases. (PDF, 118 KB)
- Table S3 - The specific pathogens bound by HLA-DRB1 allelic lineages only with fast or slow PBR substitution rate. (PDF, 127 KB)