Fig. S1. Correlation between protease production and cytotoxicity by ocular clinical S. marcescens isolates and strain PIC3611. Fig. S2. Phylogram of putative S. marcescens metalloproteases. Fig. S3. Cytotoxicity to human epithelial cell lines and protease activity of induced putative metalloprotease genes. Fig. S4. AprI inhibition of PrtS and SlpB activity and cytotoxicity by K904 supernatants. Fig. S5. LipD is necessary for secretion of SlpB. Fig. S6. SlpB is a Ca2+-regulated protease. Table S1. Oligonucleotide primers used in this study. Table S2. Metalloprotease homologs of S. marcescens strain Db11.
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