============================ group1 ========================= ----------------C2-------------- REACTOME_CELL_CYCLE_MITOTIC ( 3.2588287226369e-11 ); REACTOME_MITOTIC_PROMETAPHASE ( 2.18350066412014e-10 ); REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES ( 1.08502306157095e-09 ); REACTOME_CENTROSOME_MATURATION ( 3.17310594253085e-09 ); REACTOME_G2_M_TRANSITION ( 2.40828198067343e-08 ); REACTOME_MITOTIC_M_M_G1_PHASES ( 1.36954697781211e-07 ); BIOCARTA_ATRBRCA_PATHWAY ( 2.80831888338877e-06 ); KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS ( 5.41999406023845e-06 ); REACTOME_DNA_REPAIR ( 3.17216663971686e-05 ); REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT ( 8.75495948044723e-05 ); REACTOME_FANCONI_ANEMIA_PATHWAY ( 0.000163220150883673 ); REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION ( 0.000173219573941149 ); BIOCARTA_ATM_PATHWAY ( 0.000204603987515852 ); REACTOME_DOUBLE_STRAND_BREAK_REPAIR ( 0.000304426394241181 ); REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS ( 0.000372058442359789 ); REACTOME_MRNA_3_END_PROCESSING ( 0.000613680472828743 ); REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES ( 0.000976636977231024 ); REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR ( 0.00132057653144015 ); REACTOME_MRNA_SPLICING ( 0.00134155453787806 ); REACTOME_SIGNALLING_BY_NGF ( 0.00181715172343861 ); REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE ( 0.0020489957263709 ); BIOCARTA_NFAT_PATHWAY ( 0.00230160863658018 ); REACTOME_TRANSCRIPTION ( 0.0025434766120213 ); KEGG_BASAL_TRANSCRIPTION_FACTORS ( 0.00257414840203375 ); REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA ( 0.00269626039269221 ); REACTOME_MAP_KINASES_ACTIVATION_IN_TLR_CASCADE ( 0.00292884409886758 ); KEGG_CELL_CYCLE ( 0.0029694463908129 ); REACTOME_G2_M_CHECKPOINTS ( 0.00353819018850373 ); REACTOME_TOLL_LIKE_RECEPTOR_3_CASCADE ( 0.00374276780524188 ); REACTOME_TIE2_SIGNALING ( 0.00386628289851145 ); BIOCARTA_MET_PATHWAY ( 0.00391997538290937 ); BIOCARTA_MAPK_PATHWAY ( 0.00408163974924241 ); REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION ( 0.00424961291408279 ); REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE ( 0.00437200585266899 ); KEGG_OOCYTE_MEIOSIS ( 0.00439870973390096 ); KEGG_APOPTOSIS ( 0.00459156957351767 ); BIOCARTA_ALK_PATHWAY ( 0.00477204187660673 ); REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS ( 0.00477204187660673 ); KEGG_MTOR_SIGNALING_PATHWAY ( 0.005128483543026 ); BIOCARTA_AKAPCENTROSOME_PATHWAY ( 0.00599028037945897 ); REACTOME_DARPP32_EVENTS ( 0.00688456647631644 ); REACTOME_TOLL_RECEPTOR_CASCADES ( 0.00702085282045863 ); KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM ( 0.00761408374767754 ); KEGG_SPLICEOSOME ( 0.00844766448882181 ); BIOCARTA_HDAC_PATHWAY ( 0.00858273111431678 ); BIOCARTA_CREB_PATHWAY ( 0.00858273111431678 ); BIOCARTA_IGF1_PATHWAY ( 0.00893419820752822 ); BIOCARTA_INSULIN_PATHWAY ( 0.00893419820752822 ); KEGG_NEUROTROPHIN_SIGNALING_PATHWAY ( 0.00921248556825408 ); REACTOME_RHO_GTPASE_CYCLE ( 0.0094383935643466 ); REACTOME_SIGNALING_BY_EGFR ( 0.00958185122271079 ); ----------------C3-------------- TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P ( 9.50219887668302e-19 ); TGCACTT,MIR-519C,MIR-519B,MIR-519A ( 1.21841950461301e-17 ); TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D ( 3.20692787956333e-17 ); ATGTACA,MIR-493 ( 2.76820662007034e-16 ); TACTTGA,MIR-26A,MIR-26B ( 8.32146919355087e-16 ); TTGCACT,MIR-130A,MIR-301,MIR-130B ( 4.01567046780173e-15 ); TTTGCAC,MIR-19A,MIR-19B ( 3.17800563620292e-14 ); CTTTGTA,MIR-524 ( 4.2965914382807e-13 ); TTTTGAG,MIR-373 ( 5.47798843112198e-13 ); TTTGTAG,MIR-520D ( 7.92602379216515e-13 ); CAGTATT,MIR-200B,MIR-200C,MIR-429 ( 1.01569345854649e-12 ); GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D ( 1.15711138819373e-12 ); GCAAAAA,MIR-129 ( 5.10267527924075e-12 ); CTTGTAT,MIR-381 ( 1.32670305382325e-11 ); AAGCCAT,MIR-135A,MIR-135B ( 1.6617658591349e-11 ); TAATGTG,MIR-323 ( 1.84197006824195e-11 ); TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 ( 1.94294053757968e-11 ); ATATGCA,MIR-448 ( 2.61562097921121e-11 ); GTTATAT,MIR-410 ( 3.22439974014936e-11 ); ACCATTT,MIR-522 ( 3.90924049077809e-11 ); TGCACTG,MIR-148A,MIR-152,MIR-148B ( 6.04905160504677e-11 ); ACACTAC,MIR-142-3P ( 7.31815242138739e-11 ); ATACTGT,MIR-144 ( 9.47740542361083e-11 ); ATCATGA,MIR-433 ( 1.07446186895475e-10 ); TGCTTTG,MIR-330 ( 2.24942295257507e-10 ); ATGTTAA,MIR-302C ( 3.00092275429488e-10 ); ATTCTTT,MIR-186 ( 3.0281846929141e-10 ); ACTGAAA,MIR-30A-3P,MIR-30E-3P ( 3.59430163306239e-10 ); GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 ( 4.01938706692552e-10 ); GTTTGTT,MIR-495 ( 4.7468624621494e-10 ); ACTGTAG,MIR-139 ( 5.62552089448753e-10 ); ACATTCC,MIR-1,MIR-206 ( 6.30060690051266e-10 ); AATGTGA,MIR-23A,MIR-23B ( 1.21556393614971e-09 ); ATTACAT,MIR-380-3P ( 1.21654258905794e-09 ); ACTTTAT,MIR-142-5P ( 1.33920738245029e-09 ); RCGCANGCGY_V$NRF1_Q6 ( 1.49398845190976e-09 ); CATTTCA,MIR-203 ( 1.52516041378799e-09 ); AAGCACT,MIR-520F ( 1.68463996846565e-09 ); ATAAGCT,MIR-21 ( 1.75930841505631e-09 ); CAGTGTT,MIR-141,MIR-200A ( 2.4185379423581e-09 ); TTTGCAG,MIR-518A-2 ( 2.51944261210277e-09 ); AACTGGA,MIR-145 ( 3.53523209241332e-09 ); AGTCTTA,MIR-499 ( 4.60470497788624e-09 ); GTGCCAT,MIR-183 ( 1.43363228783719e-08 ); CAGCTTT,MIR-320 ( 4.07927223432929e-08 ); TAGCTTT,MIR-9 ( 4.68573081088661e-08 ); CTACTGT,MIR-199A ( 5.24336290775756e-08 ); CTGTTAC,MIR-194 ( 5.77607391610302e-08 ); GACTGTT,MIR-212,MIR-132 ( 6.17179494102386e-08 ); GTACTGT,MIR-101 ( 6.29215121921423e-08 ); AACATTC,MIR-409-3P ( 7.31157407589926e-08 ); AAAGGGA,MIR-204,MIR-211 ( 9.85880384509389e-08 ); TATTATA,MIR-374 ( 1.19167599045707e-07 ); CATGTAA,MIR-496 ( 1.53577068838211e-07 ); ACATATC,MIR-190 ( 2.26876927433829e-07 ); TGTATGA,MIR-485-3P ( 2.63941651291988e-07 ); CTTTGCA,MIR-527 ( 4.28243072934271e-07 ); TGCCTTA,MIR-124A ( 4.92279922215529e-07 ); TTGCCAA,MIR-182 ( 5.08741544567141e-07 ); ACACTGG,MIR-199A,MIR-199B ( 5.69178693852789e-07 ); AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D ( 8.96690650513633e-07 ); SCGGAAGY_V$ELK1_02 ( 9.07928947337466e-07 ); ATGCAGT,MIR-217 ( 1.16306736887602e-06 ); GTATGAT,MIR-154,MIR-487 ( 1.23973681851837e-06 ); TGTGTGA,MIR-377 ( 1.24468897609134e-06 ); TGCGCANK_UNKNOWN ( 1.30156651597341e-06 ); ATGCTGC,MIR-103,MIR-107 ( 1.38859819673835e-06 ); TAATAAT,MIR-126 ( 1.59320842797561e-06 ); GTATTAT,MIR-369-3P ( 1.65799391730538e-06 ); GTGCCTT,MIR-506 ( 2.49069311917847e-06 ); GTCTTCC,MIR-7 ( 2.49604864008993e-06 ); TAANNYSGCG_UNKNOWN ( 2.60840822572143e-06 ); GTGTTGA,MIR-505 ( 3.63599907774566e-06 ); GCCATNTTG_V$YY1_Q6 ( 3.95392857903192e-06 ); TGGTGCT,MIR-29A,MIR-29B,MIR-29C ( 5.09224114020422e-06 ); AGGCACT,MIR-515-3P ( 5.92681748522556e-06 ); ACCAAAG,MIR-9 ( 6.14534938443216e-06 ); V$YY1_01 ( 6.1609155297e-06 ); GTGCAAA,MIR-507 ( 6.74925193890643e-06 ); TTGGAGA,MIR-515-5P,MIR-519E ( 7.06491260838788e-06 ); GTGACTT,MIR-224 ( 8.62478604250814e-06 ); ATGTTTC,MIR-494 ( 8.62478604250814e-06 ); TGCAAAC,MIR-452 ( 9.23882095619573e-06 ); ACAACTT,MIR-382 ( 9.36239884535491e-06 ); ACTGCAG,MIR-17-3P ( 1.00499268996315e-05 ); V$NFMUE1_Q6 ( 1.17556876334023e-05 ); CAATGCA,MIR-33 ( 1.31665866933047e-05 ); TTGTTT_V$FOXO4_01 ( 1.39936081306227e-05 ); TCCCRNNRTGC_UNKNOWN ( 1.56995657813559e-05 ); TMTCGCGANR_UNKNOWN ( 1.59647896880135e-05 ); TAGGTCA,MIR-192,MIR-215 ( 1.60629937004117e-05 ); ATAGGAA,MIR-202 ( 1.94019152149546e-05 ); ACTGTGA,MIR-27A,MIR-27B ( 2.11300473949078e-05 ); GGCACTT,MIR-519E ( 2.36476494808398e-05 ); GTAAGAT,MIR-200A ( 2.61426960779412e-05 ); GGGCATT,MIR-365 ( 2.68350475845435e-05 ); CTATGCA,MIR-153 ( 2.80111510679319e-05 ); AACTTT_UNKNOWN ( 3.02935720075954e-05 ); ACTGCCT,MIR-34B ( 3.31953081586546e-05 ); KCCGNSWTTT_UNKNOWN ( 3.3505436813239e-05 ); AACTGAC,MIR-223 ( 3.73307537185806e-05 ); V$YY1_02 ( 4.01046365614742e-05 ); CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I ( 4.61006403739577e-05 ); TCATCTC,MIR-143 ( 5.89173410437211e-05 ); TACAATC,MIR-508 ( 7.57032958970654e-05 ); GCTTGAA,MIR-498 ( 9.35317171005396e-05 ); TCANNTGAY_V$SREBP1_01 ( 9.54331242098323e-05 ); GCACCTT,MIR-18A,MIR-18B ( 0.000106959303849371 ); AGCATTA,MIR-155 ( 0.000124114922676134 ); AAACCAC,MIR-140 ( 0.000125993451785782 ); TCCATTKW_UNKNOWN ( 0.000141021179751347 ); AGGAGTG,MIR-483 ( 0.00014608361616875 ); GAGACTG,MIR-452 ( 0.00016277037975368 ); AAGCAAT,MIR-137 ( 0.000170188304870249 ); ATCTTGC,MIR-31 ( 0.00017969662001471 ); GCATTTG,MIR-105 ( 0.000180626871592359 ); GTGACGY_V$E4F1_Q6 ( 0.000186391666567069 ); V$E2F1_Q4_01 ( 0.000205385542396342 ); AAGCACA,MIR-218 ( 0.000216246786789701 ); YGCANTGCR_UNKNOWN ( 0.00023535265217297 ); AAAGACA,MIR-511 ( 0.000307634289087406 ); WTGAAAT_UNKNOWN ( 0.00033826901810027 ); GCGSCMNTTT_UNKNOWN ( 0.000376603617943904 ); TCTATGA,MIR-376A,MIR-376B ( 0.000414205616529439 ); ATAACCT,MIR-154 ( 0.000464119254222728 ); V$FOXO3_01 ( 0.000470853831024824 ); ATGAAGG,MIR-205 ( 0.00050336930538673 ); CAGCACT,MIR-512-3P ( 0.000565422375592944 ); AGTCAGC,MIR-345 ( 0.0005682673602328 ); TGACAGNY_V$MEIS1_01 ( 0.000615911103321611 ); RGAANNTTC_V$HSF1_01 ( 0.00061978188190473 ); ACTACCT,MIR-196A,MIR-196B ( 0.000645838599887564 ); CACGTG_V$MYC_Q2 ( 0.000662827047077357 ); SMTTTTGT_UNKNOWN ( 0.000663940889797846 ); V$E2F_Q4_01 ( 0.000694066614776936 ); GTACAGG,MIR-486 ( 0.000748243993788705 ); GACAATC,MIR-219 ( 0.000764901659229535 ); V$SREBP1_01 ( 0.000793329692710251 ); ATGCTGG,MIR-338 ( 0.000859559878386365 ); ATACCTC,MIR-202 ( 0.000918703492226808 ); MGGAAGTG_V$GABP_B ( 0.0011376881994446 ); V$USF_01 ( 0.00119797781095899 ); V$CREB_02 ( 0.00130761243655223 ); YYCATTCAWW_UNKNOWN ( 0.00136267608525924 ); V$E2F_Q3_01 ( 0.00147580544938905 ); RTAAACA_V$FREAC2_01 ( 0.00161500849129178 ); TCCAGAT,MIR-516-5P ( 0.00172149929253537 ); GTTAAAG,MIR-302B ( 0.00199795504252753 ); ACTAYRNNNCCCR_UNKNOWN ( 0.00200842333912884 ); GGCACAT,MIR-455 ( 0.00218122630586258 ); V$GABP_B ( 0.00238026557265849 ); V$E4F1_Q6 ( 0.00245925274719984 ); CACTTTG,MIR-520G,MIR-520H ( 0.00245925274719984 ); ATGTCAC,MIR-489 ( 0.002600839085917 ); V$ARNT_02 ( 0.0027018503057962 ); KMCATNNWGGA_UNKNOWN ( 0.00273629521499048 ); V$FREAC2_01 ( 0.00275238710329126 ); GGCNKCCATNK_UNKNOWN ( 0.00282252695916629 ); ACAGGGT,MIR-10A,MIR-10B ( 0.00287674951637551 ); AATGGAG,MIR-136 ( 0.00318141172420965 ); YTATTTTNR_V$MEF2_02 ( 0.00332253211341308 ); CACTGTG,MIR-128A,MIR-128B ( 0.00344279424984569 ); GGGCGGR_V$SP1_Q6 ( 0.0034435159178193 ); V$FAC1_01 ( 0.00344771294118264 ); CGCAAAA,MIR-450 ( 0.00345687190147139 ); V$MEIS1_01 ( 0.00355779549810203 ); V$ARNT_01 ( 0.00388892320131727 ); V$PAX4_02 ( 0.00388892320131727 ); AAAGGAT,MIR-501 ( 0.00396695394811362 ); V$TITF1_Q3 ( 0.00452186033197289 ); AGGTGCA,MIR-500 ( 0.00494221976252767 ); CTTTGT_V$LEF1_Q2 ( 0.00496127972075598 ); GGTAACC,MIR-409-5P ( 0.00521860974716858 ); V$USF_02 ( 0.00523975044978641 ); V$AP3_Q6 ( 0.00523975044978641 ); TGGAAA_V$NFAT_Q4_01 ( 0.00575464054199367 ); AACGGTT,MIR-451 ( 0.00577925033153965 ); V$CREB_Q4 ( 0.00588523830839795 ); GGCAGTG,MIR-324-3P ( 0.00626211923106846 ); V$HFH3_01 ( 0.00636305480256742 ); TCCAGAG,MIR-518C ( 0.00656138407811614 ); V$FOXJ2_02 ( 0.00689591114439258 ); GGTGTGT,MIR-329 ( 0.00717585784478769 ); ATGGYGGA_UNKNOWN ( 0.00724116128511583 ); TTANTCA_UNKNOWN ( 0.00761913795228702 ); CRGAARNNNNCGA_UNKNOWN ( 0.00781290783888237 ); AAGWWRNYGGC_UNKNOWN ( 0.00785138659020072 ); GCGNNANTTCC_UNKNOWN ( 0.00785138659020072 ); CTAGGAA,MIR-384 ( 0.00803121253888177 ); CAAGGAT,MIR-362 ( 0.00803121253888177 ); V$SOX5_01 ( 0.00839256918147082 ); V$ELK1_02 ( 0.00899274518222221 ); V$E2F1_Q6_01 ( 0.00923822993286332 ); ----------------C4-------------- GCM_RAB10 ( 4.61247323867595e-17 ); GCM_ZNF198 ( 6.3164301990864e-15 ); GCM_MLL ( 1.06265908101731e-12 ); GCM_MYST2 ( 2.70683169782611e-12 ); GCM_HBP1 ( 5.85476238376274e-11 ); GCM_DFFA ( 7.1424002350412e-11 ); GCM_MAX ( 9.24037844072148e-11 ); module_277 ( 2.16853299657131e-10 ); GCM_ERBB2IP ( 2.19135983296411e-10 ); module_97 ( 5.98688268591519e-10 ); module_239 ( 2.39730869725228e-09 ); GCM_UBE2N ( 2.50302554143087e-09 ); GNF2_KPNB1 ( 4.39494740691047e-09 ); GCM_GSPT1 ( 6.11399912174622e-09 ); module_182 ( 6.56406899993622e-09 ); MORF_ATRX ( 6.63987367314037e-09 ); GNF2_RBBP6 ( 9.32464673446079e-09 ); GCM_SUFU ( 9.3468466428246e-09 ); module_261 ( 1.32561308361308e-08 ); GCM_NCAM1 ( 2.44425258785282e-08 ); GCM_CSNK1A1 ( 2.7417218362912e-08 ); GCM_RAN ( 7.30839890800766e-08 ); GNF2_DEK ( 7.7387814350477e-08 ); MORF_REV3L ( 7.87137986243941e-08 ); GCM_NF2 ( 9.38303437154565e-08 ); GCM_MAP4K4 ( 1.43391662475678e-07 ); module_358 ( 1.52497939120425e-07 ); GNF2_DDX5 ( 2.15562516730501e-07 ); MORF_BRCA1 ( 3.07866583277056e-07 ); module_98 ( 3.77799000164429e-07 ); MORF_RAP1A ( 1.19582576674514e-06 ); GNF2_SMC4L1 ( 2.36763772725441e-06 ); GCM_CHUK ( 2.60840822572143e-06 ); module_183 ( 2.60840822572143e-06 ); module_252 ( 5.20850015024622e-06 ); GCM_PTK2 ( 6.20332110052196e-06 ); GCM_RBM8A ( 7.34491054841413e-06 ); MORF_BMPR2 ( 9.55917381226215e-06 ); MORF_RFC1 ( 1.11220912148316e-05 ); module_332 ( 1.15168447580601e-05 ); GCM_IL6ST ( 1.27490492831282e-05 ); module_323 ( 1.40984826757373e-05 ); GNF2_HMMR ( 1.4593093735742e-05 ); module_331 ( 1.49452553244787e-05 ); module_198 ( 1.52965443902075e-05 ); GNF2_TTK ( 2.37336859178834e-05 ); module_54 ( 2.63915305088194e-05 ); MORF_CDC10 ( 2.8580549823965e-05 ); module_206 ( 3.69619237864676e-05 ); GCM_PPM1D ( 4.23925765871926e-05 ); MORF_CCNF ( 5.70137253975469e-05 ); GNF2_MLH1 ( 6.20590247128951e-05 ); GNF2_CDC2 ( 9.48414930441201e-05 ); GNF2_CENPF ( 9.48414930441201e-05 ); module_237 ( 9.55018463623082e-05 ); GCM_FANCL ( 0.000133296629900739 ); GNF2_HAT1 ( 0.000192897226490938 ); GCM_RAP2A ( 0.000196569402760329 ); GNF2_SMC2L1 ( 0.000196569402760329 ); module_320 ( 0.000204603987515852 ); MORF_HDAC2 ( 0.000206169237186801 ); MORF_MSH3 ( 0.000217882769436787 ); module_525 ( 0.000219805245621672 ); module_36 ( 0.000257087661717745 ); GNF2_RRM1 ( 0.000316405066077101 ); GNF2_PCNA ( 0.000323656767877845 ); MORF_EIF4E ( 0.000363498862787921 ); GCM_DLG1 ( 0.000389767736701066 ); GNF2_HDAC1 ( 0.000429174822832699 ); GNF2_RPA1 ( 0.000440672526367344 ); module_124 ( 0.000495793312270226 ); MORF_PSMF1 ( 0.000500164289603554 ); MORF_PTEN ( 0.000501644168923194 ); MORF_DCC ( 0.000552982161799793 ); GNF2_CDC20 ( 0.0005682673602328 ); GNF2_BUB1B ( 0.000606453329797785 ); GNF2_CCNB2 ( 0.000691479278117648 ); module_136 ( 0.00080387262058216 ); module_244 ( 0.00091555094364328 ); MORF_PPP5C ( 0.000917035487011176 ); GCM_DDX5 ( 0.00100601277564563 ); GCM_MAP1B ( 0.00100601277564563 ); GNF2_CCNA2 ( 0.00105854837254898 ); MORF_RFC5 ( 0.00126231072848381 ); module_229 ( 0.00126701349288336 ); module_315 ( 0.00132057653144015 ); GNF2_RFC4 ( 0.00143203936552888 ); GCM_BAG5 ( 0.00155193333005254 ); GNF2_MSH2 ( 0.00155193333005254 ); GNF2_MKI67 ( 0.00155193333005254 ); GNF2_MCM5 ( 0.00162117788773441 ); GNF2_ELAC2 ( 0.00162313862102607 ); MORF_ZNF10 ( 0.0018046501594123 ); GNF2_CKS2 ( 0.0018046501594123 ); GNF2_DENR ( 0.00196102852779908 ); module_303 ( 0.00203266751060112 ); MORF_CDC2L5 ( 0.00244209967702718 ); MORF_SS18 ( 0.00272023299484175 ); module_197 ( 0.00277333687892069 ); MORF_PAPSS1 ( 0.00278372491079334 ); module_352 ( 0.00278853704809326 ); MORF_DMPK ( 0.00283753076635837 ); module_69 ( 0.00290301437367551 ); GCM_CALM1 ( 0.00299444998739493 ); GNF2_ESPL1 ( 0.00319163804890303 ); GCM_TPR ( 0.00333958803996565 ); MORF_ERCC2 ( 0.00337073868560085 ); MORF_HAT1 ( 0.00344771294118264 ); GNF2_RRM2 ( 0.00391997538290937 ); GCM_AQP4 ( 0.0042438686651519 ); GCM_CRKL ( 0.00437200585266899 ); GCM_PTPRD ( 0.00437200585266899 ); module_372 ( 0.00522399865210997 ); MORF_ATF2 ( 0.00529503319240333 ); module_308 ( 0.00558628818667016 ); module_205 ( 0.00588469849349694 ); GCM_RAD21 ( 0.00641710012254941 ); GNF2_ANP32B ( 0.00641710012254941 ); MORF_THPO ( 0.00645580472099591 ); GNF2_TDG ( 0.00688456647631644 ); MORF_TPR ( 0.00692955194805772 ); GCM_BMPR2 ( 0.00724116128511583 ); MORF_BUB1B ( 0.00767893273505464 ); module_179 ( 0.00771476120757028 ); MORF_MLLT10 ( 0.00793433818161551 ); MORF_TTN ( 0.0082367146011368 ); GNF2_ATM ( 0.00858273111431678 ); MORF_IL16 ( 0.00876206442172919 ); module_567 ( 0.00884792986779741 ); module_253 ( 0.00893419820752822 ); module_67 ( 0.00944462748142775 ); ----------------C5-------------- NUCLEUS ( 6.75054989665282e-18 ); MICROTUBULE_CYTOSKELETON ( 2.26915236240317e-17 ); INTRACELLULAR_ORGANELLE_PART ( 3.12916155575178e-16 ); ORGANELLE_PART ( 4.88576487917934e-16 ); CENTROSOME ( 1.64330261128464e-15 ); MICROTUBULE_ORGANIZING_CENTER ( 2.58661612468646e-14 ); BIOPOLYMER_METABOLIC_PROCESS ( 1.05115941468373e-13 ); CYTOSKELETAL_PART ( 5.14670665298752e-11 ); NUCLEAR_PART ( 1.15332339739529e-10 ); CYTOSKELETON ( 3.22374563959724e-09 ); NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 3.94145517968611e-09 ); NUCLEOPLASM ( 5.66393688528884e-09 ); PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY ( 6.20149997041021e-09 ); NON_MEMBRANE_BOUND_ORGANELLE ( 8.65184892993534e-09 ); INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE ( 8.65184892993534e-09 ); CELL_CYCLE_PROCESS ( 9.33627036616116e-09 ); PHOSPHORYLATION ( 7.17780553679559e-08 ); PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 1.739973041445e-07 ); NUCLEAR_LUMEN ( 2.52456656760351e-07 ); GOLGI_APPARATUS_PART ( 3.72397433170463e-07 ); CYTOPLASM ( 5.06788505163e-07 ); CELL_CYCLE_GO_0007049 ( 5.33510865293782e-07 ); ADENYL_RIBONUCLEOTIDE_BINDING ( 1.23644625701808e-06 ); MICROTUBULE_BASED_PROCESS ( 1.49706718953418e-06 ); PROTEIN_KINASE_ACTIVITY ( 1.50146507904565e-06 ); RNA_METABOLIC_PROCESS ( 1.60699649736129e-06 ); ORGANELLE_LUMEN ( 1.66992522830762e-06 ); MEMBRANE_ENCLOSED_LUMEN ( 1.66992522830762e-06 ); SPINDLE ( 1.91068301577261e-06 ); MACROMOLECULAR_COMPLEX ( 2.05516838475394e-06 ); CELL_CYCLE_PHASE ( 2.23596105713495e-06 ); CYTOPLASMIC_PART ( 2.47972669734166e-06 ); ADENYL_NUCLEOTIDE_BINDING ( 2.60997672368413e-06 ); ATP_BINDING ( 3.52937391522571e-06 ); PHOSPHOTRANSFERASE_ACTIVITY__ALCOHOL_GROUP_AS_ACCEPTOR ( 3.68988319440135e-06 ); GOLGI_APPARATUS ( 7.01053256836137e-06 ); DNA_RECOMBINATION ( 7.0983930889678e-06 ); MITOTIC_CELL_CYCLE ( 7.40286324173495e-06 ); DNA_BINDING ( 1.55881013258239e-05 ); PROTEIN_COMPLEX ( 1.77312533521628e-05 ); PURINE_RIBONUCLEOTIDE_BINDING ( 1.82950448453034e-05 ); MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 2.37336859178834e-05 ); NUCLEOTIDE_BINDING ( 2.47369383050389e-05 ); BIOPOLYMER_MODIFICATION ( 2.971800398268e-05 ); NUCLEOPLASM_PART ( 3.21718464054904e-05 ); PURINE_NUCLEOTIDE_BINDING ( 3.21718464054904e-05 ); DNA_METABOLIC_PROCESS ( 3.25318509978928e-05 ); KINASE_ACTIVITY ( 3.25745779306625e-05 ); REGULATION_OF_NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 3.28941673089152e-05 ); TUBULIN_BINDING ( 3.4474578635617e-05 ); NEGATIVE_REGULATION_OF_NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 3.58997019325845e-05 ); UBIQUITIN_LIGASE_COMPLEX ( 4.86442009343286e-05 ); M_PHASE ( 5.20655039335077e-05 ); PROTEIN_MODIFICATION_PROCESS ( 5.29535814823649e-05 ); ORGANELLE_ORGANIZATION_AND_BIOGENESIS ( 5.59207527184419e-05 ); CELLULAR_LOCALIZATION ( 5.83189334833986e-05 ); POST_TRANSLATIONAL_PROTEIN_MODIFICATION ( 6.39917333632193e-05 ); DOUBLE_STRAND_BREAK_REPAIR ( 6.59956630203972e-05 ); GOLGI_MEMBRANE ( 7.06353232982804e-05 ); HELICASE_ACTIVITY ( 7.49410550625609e-05 ); INTRACELLULAR_TRANSPORT ( 8.22165899900374e-05 ); RESPONSE_TO_DNA_DAMAGE_STIMULUS ( 8.25100935981995e-05 ); ESTABLISHMENT_OF_CELLULAR_LOCALIZATION ( 0.000102216140735319 ); RNA_PROCESSING ( 0.000111448067658503 ); NEGATIVE_REGULATION_OF_TRANSCRIPTION ( 0.000116851708021644 ); TRANSFERASE_ACTIVITY__TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS ( 0.000151468906585041 ); TRANSCRIPTION ( 0.000153554259469205 ); NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.000158983784086846 ); SPINDLE_MICROTUBULE ( 0.000163220150883673 ); NEGATIVE_REGULATION_OF_METABOLIC_PROCESS ( 0.000189201228259511 ); MICROTUBULE_ASSOCIATED_COMPLEX ( 0.000192897226490938 ); NEGATIVE_REGULATION_OF_CELLULAR_PROCESS ( 0.000212330256595892 ); CHROMOSOME ( 0.00024138598010958 ); DNA_REPAIR ( 0.00024138598010958 ); MICROTUBULE_MOTOR_ACTIVITY ( 0.000267555729611775 ); TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER ( 0.000281858947018657 ); REGULATION_OF_DNA_METABOLIC_PROCESS ( 0.000308348674481576 ); TRANSCRIPTION__DNA_DEPENDENT ( 0.000323791878301042 ); NUCLEAR_BODY ( 0.000356915943185314 ); MICROTUBULE_BINDING ( 0.000356915943185314 ); RNA_BIOSYNTHETIC_PROCESS ( 0.00035837613414202 ); M_PHASE_OF_MITOTIC_CELL_CYCLE ( 0.00037040147108864 ); REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.000388771984711019 ); GOLGI_ASSOCIATED_VESICLE ( 0.000410189651249667 ); SPINDLE_POLE ( 0.000419450947350987 ); MEIOTIC_RECOMBINATION ( 0.000419450947350987 ); DNA_DEPENDENT_ATPASE_ACTIVITY ( 0.000440672526367344 ); ENZYME_BINDING ( 0.000470853831024824 ); TRANSCRIPTION_ACTIVATOR_ACTIVITY ( 0.000516269389657978 ); CYTOPLASMIC_VESICLE ( 0.000571218184735879 ); MRNA_METABOLIC_PROCESS ( 0.000586209664707595 ); REGULATION_OF_METABOLIC_PROCESS ( 0.000631496393892869 ); ATPASE_ACTIVITY ( 0.000684526870508278 ); CELL_CYCLE_CHECKPOINT_GO_0000075 ( 0.000748243993788705 ); MITOSIS ( 0.000792514546085821 ); RESPONSE_TO_ENDOGENOUS_STIMULUS ( 0.000814880540377665 ); KINESIN_COMPLEX ( 0.000857633979217556 ); DNA_HELICASE_ACTIVITY ( 0.000860329563291351 ); CYTOPLASMIC_MEMBRANE_BOUND_VESICLE ( 0.000876314013080757 ); NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS ( 0.000882914731321244 ); VESICLE ( 0.00103521527594348 ); REGULATION_OF_TRANSCRIPTION ( 0.00107971517215055 ); MEMBRANE_BOUND_VESICLE ( 0.00111268386391153 ); KINETOCHORE ( 0.0011658409871812 ); KINASE_BINDING ( 0.00126231072848381 ); MEIOSIS_I ( 0.00131223697961661 ); ENDOMEMBRANE_SYSTEM ( 0.00132279378708331 ); ATPASE_ACTIVITY__COUPLED ( 0.00133435278942757 ); CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.00160131943502103 ); MAGNESIUM_ION_BINDING ( 0.00169557455028798 ); NUCLEAR_UBIQUITIN_LIGASE_COMPLEX ( 0.00174023790600839 ); ENDODEOXYRIBONUCLEASE_ACTIVITY ( 0.00174023790600839 ); MITOTIC_CELL_CYCLE_CHECKPOINT ( 0.00181614227230433 ); REGULATION_OF_GENE_EXPRESSION ( 0.00182390710000087 ); MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS ( 0.00195238901253717 ); CHROMOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00195433899934745 ); REGULATION_OF_ORGANELLE_ORGANIZATION_AND_BIOGENESIS ( 0.00196102852779908 ); DNA_DIRECTED_RNA_POLYMERASE_II__HOLOENZYME ( 0.00200356861007376 ); PROTEIN_TRANSPORT ( 0.00200599809006758 ); PROTEIN_KINASE_CASCADE ( 0.00237001369625679 ); ER_GOLGI_INTERMEDIATE_COMPARTMENT ( 0.00245802815374158 ); I_KAPPAB_KINASE_NF_KAPPAB_CASCADE ( 0.00257438853333702 ); GOLGI_VESICLE_TRANSPORT ( 0.00261908201232959 ); MOTOR_ACTIVITY ( 0.00262318215442749 ); STRUCTURE_SPECIFIC_DNA_BINDING ( 0.00272023299484175 ); INTRACELLULAR_PROTEIN_TRANSPORT ( 0.00296527045042222 ); PROTEIN_KINASE_BINDING ( 0.00318141172420965 ); INDUCTION_OF_APOPTOSIS_BY_INTRACELLULAR_SIGNALS ( 0.00326107193676862 ); RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00344731000812085 ); NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY ( 0.00386542676972603 ); CYTOSKELETAL_PROTEIN_BINDING ( 0.0040901136890804 ); REGULATION_OF_TRANSCRIPTION__DNA_DEPENDENT ( 0.00413064056832868 ); GOLGI_STACK ( 0.00415719237937275 ); RNA_HELICASE_ACTIVITY ( 0.00424961291408279 ); RAS_GTPASE_BINDING ( 0.00424961291408279 ); CHROMOSOME__PERICENTRIC_REGION ( 0.00521860974716858 ); MICROTUBULE ( 0.00521860974716858 ); CHROMOSOME_SEGREGATION ( 0.00521860974716858 ); REGULATION_OF_RNA_METABOLIC_PROCESS ( 0.00522129711866424 ); MICROTUBULE_ORGANIZING_CENTER_PART ( 0.00522399865210997 ); PYROPHOSPHATASE_ACTIVITY ( 0.00524927209805913 ); PROTEIN_C_TERMINUS_BINDING ( 0.00528004253659741 ); CHROMOSOMAL_PART ( 0.00528748218509377 ); TRANSCRIPTION_COACTIVATOR_ACTIVITY ( 0.00535487552092572 ); ENDONUCLEASE_ACTIVITY ( 0.00544885755232231 ); RNA_SPLICING ( 0.00557069719009706 ); MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS ( 0.00577925033153965 ); RESPONSE_TO_IONIZING_RADIATION ( 0.00577925033153965 ); REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER ( 0.00594866518951618 ); HYDROLASE_ACTIVITY__ACTING_ON_ACID_ANHYDRIDES ( 0.00600456466244579 ); ATP_DEPENDENT_HELICASE_ACTIVITY ( 0.00688456647631644 ); ESTABLISHMENT_OF_PROTEIN_LOCALIZATION ( 0.00711341326134035 ); MRNA_PROCESSING_GO_0006397 ( 0.00724116128511583 ); MACROMOLECULE_LOCALIZATION ( 0.0073064647305998 ); BASOLATERAL_PLASMA_MEMBRANE ( 0.00781290783888237 ); CONDENSED_CHROMOSOME ( 0.00781290783888237 ); TRANSCRIPTION_FACTOR_BINDING ( 0.00787354995908189 ); CYSTEINE_TYPE_PEPTIDASE_ACTIVITY ( 0.00803121253888177 ); CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY ( 0.00820629347495486 ); CENTROSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00832513230346839 ); DNA_REPLICATION_INITIATION ( 0.00832513230346839 ); REGULATION_OF_CELL_CYCLE ( 0.00859925759918801 ); REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE ( 0.00875831990738202 ); NUCLEAR_SPECK ( 0.00894851902495657 ); SPINDLE_ORGANIZATION_AND_BIOGENESIS ( 0.00894851902495657 ); DNA_DEPENDENT_DNA_REPLICATION ( 0.00923936066541298 ); GTPASE_BINDING ( 0.00942483381945119 ); CELLULAR_PROTEIN_METABOLIC_PROCESS ( 0.00985374076688834 ); ----------------GOSLIM-------------- GO:0005622 intracellular ( 1.42720507668155e-62 ); GO:0005634 nucleus ( 2.36448906753963e-62 ); GO:0044424 intracellular part ( 5.47788424335496e-52 ); GO:0034960 cellular biopolymer metabolic process ( 1.44232467152528e-30 ); GO:0043283 biopolymer metabolic process ( 3.49621805270322e-29 ); GO:0043229 intracellular organelle ( 7.84287367142734e-27 ); GO:0043226 organelle ( 5.80367248060406e-25 ); GO:0044260 cellular macromolecule metabolic process ( 6.1457003343079e-21 ); GO:0043170 macromolecule metabolic process ( 1.10836992997178e-19 ); GO:0043227 membrane-bounded organelle ( 1.43558771218953e-19 ); GO:0043231 intracellular membrane-bounded organelle ( 2.68470245087577e-18 ); GO:0005488 binding ( 1.29872512424039e-17 ); GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 4.55048731461342e-16 ); GO:0003676 nucleic acid binding ( 4.11042587701609e-15 ); GO:0044238 primary metabolic process ( 4.38960996284535e-15 ); GO:0016070 RNA metabolic process ( 8.72153528439934e-14 ); GO:0000166 nucleotide binding ( 2.02269698582742e-13 ); GO:0044237 cellular metabolic process ( 4.2925175702107e-13 ); GO:0005524 ATP binding ( 1.06335831361759e-11 ); GO:0032559 adenyl ribonucleotide binding ( 2.00351475231391e-11 ); GO:0044428 nuclear part ( 9.64245879063134e-11 ); GO:0030554 adenyl nucleotide binding ( 2.48660202437836e-09 ); GO:0015630 microtubule cytoskeleton ( 8.87131591921154e-09 ); GO:0005815 microtubule organizing center ( 5.91324975023301e-08 ); GO:0032553 ribonucleotide binding ( 1.30319773059641e-06 ); GO:0032555 purine ribonucleotide binding ( 4.1409979360917e-06 ); GO:0005813 centrosome ( 5.44917358044676e-06 ); GO:0010467 gene expression ( 1.41923651087223e-05 ); GO:0017076 purine nucleotide binding ( 4.75036496523854e-05 ); GO:0008152 metabolic process ( 0.00126910184696204 ); GO:0008270 zinc ion binding ( 0.00152609489913708 ); GO:0006974 response to DNA damage stimulus ( 0.0018564249342045 ); GO:0031981 nuclear lumen ( 0.00218049228580985 ); GO:0005654 nucleoplasm ( 0.00698700873892904 ); GO:0044422 organelle part ( 0.00868080801108015 ); GO:0044446 intracellular organelle part ( 1.42720507668155e-62 ); GO:0003677 DNA binding ( 2.36448906753963e-62 ); GO:0005515 protein binding ( 5.47788424335496e-52 ); GO:0006281 DNA repair ( 1.44232467152528e-30 ); GO:0034984 cellular response to DNA damage stimulus ( 3.49621805270322e-29 ); GO:0009987 cellular process ( 7.84287367142734e-27 ); GO:0003674 molecular_function ( 5.80367248060406e-25 ); GO:0044464 cell part ( 6.1457003343079e-21 ); GO:0005623 cell ( 1.10836992997178e-19 ); GO:0070013 intracellular organelle lumen ( 1.43558771218953e-19 ); GO:0034961 cellular biopolymer biosynthetic process ( 2.68470245087577e-18 ); GO:0043284 biopolymer biosynthetic process ( 1.29872512424039e-17 ); GO:0051301 cell division ( 4.55048731461342e-16 ); GO:0006350 transcription ( 4.11042587701609e-15 ); GO:0033554 cellular response to stress ( 4.38960996284535e-15 ); GO:0031974 membrane-enclosed lumen ( 8.72153528439934e-14 ); GO:0003723 RNA binding ( 2.02269698582742e-13 ); GO:0043233 organelle lumen ( 4.2925175702107e-13 ); GO:0009059 macromolecule biosynthetic process ( 1.06335831361759e-11 ); GO:0034645 cellular macromolecule biosynthetic process ( 2.00351475231391e-11 ); GO:0005737 cytoplasm ( 9.64245879063134e-11 ); GO:0007049 cell cycle ( 2.48660202437836e-09 ); GO:0046914 transition metal ion binding ( 8.87131591921154e-09 ); GO:0006396 RNA processing ( 5.91324975023301e-08 ); GO:0006259 DNA metabolic process ( 1.30319773059641e-06 ); GO:0006511 ubiquitin-dependent protein catabolic process ( 4.1409979360917e-06 ); GO:0019941 modification-dependent protein catabolic process ( 5.44917358044676e-06 ); GO:0043632 modification-dependent macromolecule catabolic process ( 1.41923651087223e-05 ); GO:0051603 proteolysis involved in cellular protein catabolic process ( 4.75036496523854e-05 ); GO:0051716 cellular response to stimulus ( 0.00126910184696204 ); GO:0034962 cellular biopolymer catabolic process ( 0.00152609489913708 ); GO:0044257 cellular protein catabolic process ( 0.0018564249342045 ); GO:0004386 helicase activity ( 0.00218049228580985 ); GO:0004674 protein serine/threonine kinase activity ( 0.00698700873892904 ); GO:0043228 non-membrane-bounded organelle ( 0.00868080801108015 ); GO:0043232 intracellular non-membrane-bounded organelle ( 1.42720507668155e-62 ); GO:0060255 regulation of macromolecule metabolic process ( 2.36448906753963e-62 ); GO:0032774 RNA biosynthetic process ( 5.47788424335496e-52 ); GO:0017111 nucleoside-triphosphatase activity ( 1.44232467152528e-30 ); GO:0022403 cell cycle phase ( 3.49621805270322e-29 ); GO:0000279 M phase ( 7.84287367142734e-27 ); GO:0010556 regulation of macromolecule biosynthetic process ( 5.80367248060406e-25 ); GO:0006351 transcription, DNA-dependent ( 6.1457003343079e-21 ); GO:0030163 protein catabolic process ( 1.10836992997178e-19 ); GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 1.43558771218953e-19 ); GO:0045449 regulation of transcription ( 2.68470245087577e-18 ); GO:0010468 regulation of gene expression ( 1.29872512424039e-17 ); GO:0000087 M phase of mitotic cell cycle ( 4.55048731461342e-16 ); GO:0051252 regulation of RNA metabolic process ( 4.11042587701609e-15 ); GO:0043285 biopolymer catabolic process ( 4.38960996284535e-15 ); GO:0016462 pyrophosphatase activity ( 8.72153528439934e-14 ); GO:0016604 nuclear body ( 2.02269698582742e-13 ); GO:0005694 chromosome ( 4.2925175702107e-13 ); GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ( 1.06335831361759e-11 ); GO:0006996 organelle organization ( 2.00351475231391e-11 ); GO:0000280 nuclear division ( 9.64245879063134e-11 ); GO:0007067 mitosis ( 2.48660202437836e-09 ); GO:0048285 organelle fission ( 8.87131591921154e-09 ); GO:0016817 hydrolase activity, acting on acid anhydrides ( 5.91324975023301e-08 ); GO:0006355 regulation of transcription, DNA-dependent ( 1.30319773059641e-06 ); GO:0008380 RNA splicing ( 4.1409979360917e-06 ); GO:0033036 macromolecule localization ( 5.44917358044676e-06 ); GO:0044451 nucleoplasm part ( 1.41923651087223e-05 ); GO:0031323 regulation of cellular metabolic process ( 4.75036496523854e-05 ); GO:0016071 mRNA metabolic process ( 0.00126910184696204 ); GO:0000278 mitotic cell cycle ( 0.00152609489913708 ); GO:0022402 cell cycle process ( 0.0018564249342045 ); GO:0031326 regulation of cellular biosynthetic process ( 0.00218049228580985 ); GO:0009889 regulation of biosynthetic process ( 0.00698700873892904 ); GO:0030695 GTPase regulator activity ( 0.00868080801108015 ); GO:0046907 intracellular transport ( 1.42720507668155e-62 ); GO:0004672 protein kinase activity ( 2.36448906753963e-62 ); GO:0019222 regulation of metabolic process ( 5.47788424335496e-52 ); GO:0006397 mRNA processing ( 1.44232467152528e-30 ); GO:0016772 transferase activity, transferring phosphorus-containing groups ( 3.49621805270322e-29 ); GO:0016607 nuclear speck ( 7.84287367142734e-27 ); GO:0005819 spindle ( 5.80367248060406e-25 ); GO:0051641 cellular localization ( 6.1457003343079e-21 ); GO:0008104 protein localization ( 1.10836992997178e-19 ); GO:0015031 protein transport ( 1.43558771218953e-19 ); GO:0044265 cellular macromolecule catabolic process ( 2.68470245087577e-18 ); GO:0045184 establishment of protein localization ( 1.29872512424039e-17 ); GO:0043412 biopolymer modification ( 4.55048731461342e-16 ); GO:0016773 phosphotransferase activity, alcohol group as acceptor ( 4.11042587701609e-15 ); GO:0003824 catalytic activity ( 4.38960996284535e-15 ); GO:0016301 kinase activity ( 8.72153528439934e-14 ); GO:0008150 biological_process ( 2.02269698582742e-13 ); GO:0051649 establishment of localization in cell ( 4.2925175702107e-13 ); GO:0009057 macromolecule catabolic process ( 1.06335831361759e-11 ); GO:0005856 cytoskeleton ( 2.00351475231391e-11 ); GO:0006464 protein modification process ( 9.64245879063134e-11 ); GO:0006468 protein amino acid phosphorylation ( 2.48660202437836e-09 ); GO:0044430 cytoskeletal part ( 8.87131591921154e-09 ); GO:0000151 ubiquitin ligase complex ( 5.91324975023301e-08 ); GO:0016740 transferase activity ( 1.30319773059641e-06 ); GO:0016310 phosphorylation ( 4.1409979360917e-06 ); GO:0046872 metal ion binding ( 5.44917358044676e-06 ); GO:0043687 post-translational protein modification ( 1.41923651087223e-05 ); GO:0016887 ATPase activity ( 4.75036496523854e-05 ); GO:0044267 cellular protein metabolic process ( 0.00126910184696204 ); GO:0005096 GTPase activator activity ( 0.00152609489913708 ); GO:0006793 phosphorus metabolic process ( 0.0018564249342045 ); GO:0006796 phosphate metabolic process ( 0.00218049228580985 ); GO:0016043 cellular component organization ( 0.00698700873892904 ); GO:0019538 protein metabolic process ( 0.00868080801108015 ); GO:0008026 ATP-dependent helicase activity ( 1.42720507668155e-62 ); GO:0070035 purine NTP-dependent helicase activity ( 2.36448906753963e-62 ); GO:0019899 enzyme binding ( 5.47788424335496e-52 ); GO:0007017 microtubule-based process ( 1.44232467152528e-30 ); GO:0051276 chromosome organization ( 3.49621805270322e-29 ); GO:0044249 cellular biosynthetic process ( 7.84287367142734e-27 ); GO:0009058 biosynthetic process ( 5.80367248060406e-25 ); GO:0004221 ubiquitin thiolesterase activity ( 6.1457003343079e-21 ); GO:0043167 ion binding ( 1.10836992997178e-19 ); GO:0000793 condensed chromosome ( 1.43558771218953e-19 ); GO:0007059 chromosome segregation ( 2.68470245087577e-18 ); GO:0044427 chromosomal part ( 1.29872512424039e-17 ); GO:0043234 protein complex ( 4.55048731461342e-16 ); GO:0000226 microtubule cytoskeleton organization ( 4.11042587701609e-15 ); GO:0042623 ATPase activity, coupled ( 4.38960996284535e-15 ); GO:0005794 Golgi apparatus ( 8.72153528439934e-14 ); GO:0008047 enzyme activator activity ( 2.02269698582742e-13 ); GO:0006310 DNA recombination ( 4.2925175702107e-13 ); GO:0006302 double-strand break repair ( 1.06335831361759e-11 ); GO:0032991 macromolecular complex ( 2.00351475231391e-11 ); GO:0006886 intracellular protein transport ( 9.64245879063134e-11 ); GO:0000075 cell cycle checkpoint ( 2.48660202437836e-09 ); GO:0006260 DNA replication ( 8.87131591921154e-09 ); GO:0000375 RNA splicing, via transesterification reactions ( 5.91324975023301e-08 ); GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile ( 1.30319773059641e-06 ); GO:0000398 nuclear mRNA splicing, via spliceosome ( 4.1409979360917e-06 ); GO:0016790 thiolester hydrolase activity ( 5.44917358044676e-06 ); GO:0043169 cation binding ( 1.41923651087223e-05 ); GO:0034613 cellular protein localization ( 4.75036496523854e-05 ); GO:0044248 cellular catabolic process ( 0.00126910184696204 ); GO:0005730 nucleolus ( 0.00152609489913708 ); GO:0005083 small GTPase regulator activity ( 0.0018564249342045 ); GO:0005874 microtubule ( 0.00218049228580985 ); GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00698700873892904 ); GO:0007094 mitotic cell cycle spindle assembly checkpoint ( 0.00868080801108015 ); GO:0031577 spindle checkpoint ( 1.42720507668155e-62 ); GO:0050794 regulation of cellular process ( 2.36448906753963e-62 ); GO:0031461 cullin-RING ubiquitin ligase complex ( 5.47788424335496e-52 ); GO:0031324 negative regulation of cellular metabolic process ( 1.44232467152528e-30 ); GO:0010605 negative regulation of macromolecule metabolic process ( 3.49621805270322e-29 ); GO:0016787 hydrolase activity ( 7.84287367142734e-27 ); GO:0031119 tRNA pseudouridine synthesis ( 5.80367248060406e-25 ); GO:0008234 cysteine-type peptidase activity ( 6.1457003343079e-21 ); GO:0000228 nuclear chromosome ( 1.10836992997178e-19 ); GO:0005876 spindle microtubule ( 1.43558771218953e-19 ); GO:0031023 microtubule organizing center organization ( 2.68470245087577e-18 ); GO:0051297 centrosome organization ( 1.29872512424039e-17 ); GO:0005099 Ras GTPase activator activity ( 4.55048731461342e-16 ); GO:0051018 protein kinase A binding ( 4.11042587701609e-15 ); GO:0006508 proteolysis ( 4.38960996284535e-15 ); GO:0007093 mitotic cell cycle checkpoint ( 8.72153528439934e-14 ); GO:0015631 tubulin binding ( 2.02269698582742e-13 ); GO:0000775 chromosome, centromeric region ( 4.2925175702107e-13 ); GO:0016591 DNA-directed RNA polymerase II, holoenzyme ( 1.06335831361759e-11 ); GO:0000776 kinetochore ( 2.00351475231391e-11 ); GO:0048523 negative regulation of cellular process ( 9.64245879063134e-11 ); GO:0043087 regulation of GTPase activity ( 2.48660202437836e-09 ); GO:0003777 microtubule motor activity ( 8.87131591921154e-09 ); GO:0051020 GTPase binding ( 5.91324975023301e-08 ); GO:0050789 regulation of biological process ( 1.30319773059641e-06 ); GO:0010558 negative regulation of macromolecule biosynthetic process ( 4.1409979360917e-06 ); GO:0005798 Golgi-associated vesicle ( 5.44917358044676e-06 ); GO:0016563 transcription activator activity ( 1.41923651087223e-05 ); GO:0009056 catabolic process ( 4.75036496523854e-05 ); GO:0009892 negative regulation of metabolic process ( 0.00126910184696204 ); GO:0009890 negative regulation of biosynthetic process ( 0.00152609489913708 ); GO:0030234 enzyme regulator activity ( 0.0018564249342045 ); GO:0007131 reciprocal meiotic recombination ( 0.00218049228580985 ); GO:0003684 damaged DNA binding ( 0.00698700873892904 ); GO:0008094 DNA-dependent ATPase activity ( 0.00868080801108015 ); GO:0007243 protein kinase cascade ( 1.42720507668155e-62 ); GO:0044450 microtubule organizing center part ( 2.36448906753963e-62 ); GO:0031327 negative regulation of cellular biosynthetic process ( 5.47788424335496e-52 ); GO:0005575 cellular_component ( 1.44232467152528e-30 ); GO:0000723 telomere maintenance ( 3.49621805270322e-29 ); GO:0010212 response to ionizing radiation ( 7.84287367142734e-27 ); GO:0032200 telomere organization ( 5.80367248060406e-25 ); GO:0004843 ubiquitin-specific protease activity ( 6.1457003343079e-21 ); GO:0042770 DNA damage response, signal transduction ( 1.10836992997178e-19 ); GO:0016568 chromatin modification ( 1.43558771218953e-19 ); GO:0005875 microtubule associated complex ( 2.68470245087577e-18 ); GO:0050657 nucleic acid transport ( 1.29872512424039e-17 ); GO:0050658 RNA transport ( 4.55048731461342e-16 ); GO:0051236 establishment of RNA localization ( 4.11042587701609e-15 ); GO:0000779 condensed chromosome, centromeric region ( 4.38960996284535e-15 ); GO:0051056 regulation of small GTPase mediated signal transduction ( 8.72153528439934e-14 ); GO:0019783 small conjugating protein-specific protease activity ( 2.02269698582742e-13 ); GO:0031625 ubiquitin protein ligase binding ( 4.2925175702107e-13 ); GO:0005681 spliceosome ( 1.06335831361759e-11 ); GO:0043566 structure-specific DNA binding ( 2.00351475231391e-11 ); GO:0007242 intracellular signaling cascade ( 9.64245879063134e-11 ); GO:0016481 negative regulation of transcription ( 2.48660202437836e-09 ); GO:0000019 regulation of mitotic recombination ( 8.87131591921154e-09 ); GO:0048478 replication fork protection ( 5.91324975023301e-08 ); GO:0000940 outer kinetochore of condensed chromosome ( 1.30319773059641e-06 ); GO:0000405 bubble DNA binding ( 4.1409979360917e-06 ); GO:0006403 RNA localization ( 5.44917358044676e-06 ); GO:0016881 acid-amino acid ligase activity ( 1.41923651087223e-05 ); GO:0000796 condensin complex ( 4.75036496523854e-05 ); GO:0000922 spindle pole ( 0.00126910184696204 ); GO:0048519 negative regulation of biological process ( 0.00152609489913708 ); GO:0005097 Rab GTPase activator activity ( 0.0018564249342045 ); GO:0007010 cytoskeleton organization ( 0.00218049228580985 ); GO:0019787 small conjugating protein ligase activity ( 0.00698700873892904 ); GO:0016303 1-phosphatidylinositol-3-kinase activity ( 0.00868080801108015 ); GO:0016363 nuclear matrix ( 1.42720507668155e-62 ); GO:0000819 sister chromatid segregation ( 2.36448906753963e-62 ); GO:0000794 condensed nuclear chromosome ( 5.47788424335496e-52 ); GO:0044431 Golgi apparatus part ( 1.44232467152528e-30 ); GO:0000781 chromosome, telomeric region ( 3.49621805270322e-29 ); GO:0010629 negative regulation of gene expression ( 7.84287367142734e-27 ); GO:0000777 condensed chromosome kinetochore ( 5.80367248060406e-25 ); GO:0003678 DNA helicase activity ( 6.1457003343079e-21 ); GO:0032318 regulation of Ras GTPase activity ( 1.10836992997178e-19 ); GO:0035004 phosphoinositide 3-kinase activity ( 1.43558771218953e-19 ); GO:0016874 ligase activity ( 2.68470245087577e-18 ); GO:0007018 microtubule-based movement ( 1.29872512424039e-17 ); GO:0000217 DNA secondary structure binding ( 4.55048731461342e-16 ); GO:0034399 nuclear periphery ( 4.11042587701609e-15 ); GO:0006913 nucleocytoplasmic transport ( 4.38960996284535e-15 ); GO:0018209 peptidyl-serine modification ( 8.72153528439934e-14 ); GO:0051052 regulation of DNA metabolic process ( 2.02269698582742e-13 ); GO:0008017 microtubule binding ( 4.2925175702107e-13 ); GO:0006605 protein targeting ( 1.06335831361759e-11 ); GO:0065007 biological regulation ( 2.00351475231391e-11 ); GO:0051169 nuclear transport ( 9.64245879063134e-11 ); GO:0004842 ubiquitin-protein ligase activity ( 2.48660202437836e-09 ); GO:0004003 ATP-dependent DNA helicase activity ( 8.87131591921154e-09 ); GO:0035091 phosphoinositide binding ( 5.91324975023301e-08 ); GO:0044444 cytoplasmic part ( 1.30319773059641e-06 ); GO:0016564 transcription repressor activity ( 4.1409979360917e-06 ); GO:0044454 nuclear chromosome part ( 5.44917358044676e-06 ); GO:0032313 regulation of Rab GTPase activity ( 1.41923651087223e-05 ); GO:0032482 Rab protein signal transduction ( 4.75036496523854e-05 ); GO:0032483 regulation of Rab protein signal transduction ( 0.00126910184696204 ); GO:0000077 DNA damage checkpoint ( 0.00152609489913708 ); GO:0000245 spliceosome assembly ( 0.0018564249342045 ); GO:0000287 magnesium ion binding ( 0.00218049228580985 ); GO:0045898 regulation of transcriptional preinitiation complex assembly ( 0.00698700873892904 ); GO:0005828 kinetochore microtubule ( 0.00868080801108015 ); GO:0005955 calcineurin complex ( 1.42720507668155e-62 ); GO:0003918 DNA topoisomerase (ATP-hydrolyzing) activity ( 2.36448906753963e-62 ); GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity ( 5.47788424335496e-52 ); GO:0010165 response to X-ray ( 1.44232467152528e-30 ); GO:0042826 histone deacetylase binding ( 3.49621805270322e-29 ); GO:0007098 centrosome cycle ( 7.84287367142734e-27 ); GO:0007050 cell cycle arrest ( 5.80367248060406e-25 ); GO:0051325 interphase ( 6.1457003343079e-21 ); GO:0003690 double-stranded DNA binding ( 1.10836992997178e-19 ); GO:0006325 establishment or maintenance of chromatin architecture ( 1.43558771218953e-19 ); GO:0018105 peptidyl-serine phosphorylation ( 2.68470245087577e-18 ); GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport ( 1.29872512424039e-17 ); GO:0006312 mitotic recombination ( 4.55048731461342e-16 ); GO:0051298 centrosome duplication ( 4.11042587701609e-15 ); GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ( 4.38960996284535e-15 ); GO:0008318 protein prenyltransferase activity ( 8.72153528439934e-14 ); GO:0006366 transcription from RNA polymerase II promoter ( 2.02269698582742e-13 ); GO:0009966 regulation of signal transduction ( 4.2925175702107e-13 ); GO:0043933 macromolecular complex subunit organization ( 1.06335831361759e-11 ); GO:0030705 cytoskeleton-dependent intracellular transport ( 2.00351475231391e-11 ); GO:0000152 nuclear ubiquitin ligase complex ( 9.64245879063134e-11 ); GO:0034621 cellular macromolecular complex subunit organization ( 2.48660202437836e-09 ); GO:0032446 protein modification by small protein conjugation ( 8.87131591921154e-09 ); GO:0051329 interphase of mitotic cell cycle ( 5.91324975023301e-08 ); GO:0006400 tRNA modification ( 1.30319773059641e-06 ); GO:0007026 negative regulation of microtubule depolymerization ( 4.1409979360917e-06 ); GO:0031114 regulation of microtubule depolymerization ( 5.44917358044676e-06 ); GO:0000070 mitotic sister chromatid segregation ( 1.41923651087223e-05 ); GO:0048471 perinuclear region of cytoplasm ( 4.75036496523854e-05 ); GO:0060249 anatomical structure homeostasis ( 0.00126910184696204 ); GO:0007126 meiosis ( 0.00152609489913708 ); GO:0051321 meiotic cell cycle ( 0.0018564249342045 ); GO:0051327 M phase of meiotic cell cycle ( 0.00218049228580985 ); GO:0006261 DNA-dependent DNA replication ( 0.00698700873892904 ); GO:0051028 mRNA transport ( 0.00868080801108015 ); GO:0016192 vesicle-mediated transport ( 1.42720507668155e-62 ); GO:0030528 transcription regulator activity ( 2.36448906753963e-62 ); GO:0003713 transcription coactivator activity ( 5.47788424335496e-52 ); GO:0051640 organelle localization ( 1.44232467152528e-30 ); GO:0005793 ER-Golgi intermediate compartment ( 3.49621805270322e-29 ); GO:0000018 regulation of DNA recombination ( 7.84287367142734e-27 ); GO:0000784 nuclear chromosome, telomeric region ( 5.80367248060406e-25 ); GO:0003682 chromatin binding ( 6.1457003343079e-21 ); GO:0003724 RNA helicase activity ( 1.10836992997178e-19 ); GO:0004402 histone acetyltransferase activity ( 1.43558771218953e-19 ); GO:0004468 lysine N-acetyltransferase activity ( 2.68470245087577e-18 ); GO:0031252 cell leading edge ( 1.29872512424039e-17 ); GO:0005080 protein kinase C binding ( 4.55048731461342e-16 ); GO:0015924 mannosyl-oligosaccharide mannosidase activity ( 4.11042587701609e-15 ); GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade ( 4.38960996284535e-15 ); GO:0007019 microtubule depolymerization ( 8.72153528439934e-14 ); GO:0031111 negative regulation of microtubule polymerization or depolymerization ( 2.02269698582742e-13 ); GO:0046854 phosphoinositide phosphorylation ( 4.2925175702107e-13 ); GO:0048284 organelle fusion ( 1.06335831361759e-11 ); GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator ( 2.00351475231391e-11 ); GO:0010225 response to UV-C ( 9.64245879063134e-11 ); GO:0042772 DNA damage response, signal transduction resulting in transcription ( 2.48660202437836e-09 ); GO:0051123 transcriptional preinitiation complex assembly ( 8.87131591921154e-09 ); GO:0004652 polynucleotide adenylyltransferase activity ( 5.91324975023301e-08 ); GO:0045502 dynein binding ( 1.30319773059641e-06 ); GO:0031570 DNA integrity checkpoint ( 4.1409979360917e-06 ); GO:0051053 negative regulation of DNA metabolic process ( 5.44917358044676e-06 ); GO:0000139 Golgi membrane ( 1.41923651087223e-05 ); GO:0007249 I-kappaB kinase/NF-kappaB cascade ( 4.75036496523854e-05 ); GO:0030330 DNA damage response, signal transduction by p53 class mediator ( 0.00126910184696204 ); GO:0005635 nuclear envelope ( 0.00152609489913708 ); GO:0008134 transcription factor binding ( 0.0018564249342045 ); GO:0017016 Ras GTPase binding ( 0.00218049228580985 ); GO:0010627 regulation of protein kinase cascade ( 0.00698700873892904 ); GO:0001675 acrosome formation ( 0.00868080801108015 ); GO:0007079 mitotic chromosome movement towards spindle pole ( 1.42720507668155e-62 ); GO:0031297 replication fork processing ( 2.36448906753963e-62 ); GO:0040016 embryonic cleavage ( 5.47788424335496e-52 ); GO:0045899 positive regulation of transcriptional preinitiation complex assembly ( 1.44232467152528e-30 ); GO:0050858 negative regulation of antigen receptor-mediated signaling pathway ( 3.49621805270322e-29 ); GO:0050860 negative regulation of T cell receptor signaling pathway ( 7.84287367142734e-27 ); GO:0051300 spindle pole body organization ( 5.80367248060406e-25 ); GO:0060009 Sertoli cell development ( 6.1457003343079e-21 ); GO:0005968 Rab-protein geranylgeranyltransferase complex ( 1.10836992997178e-19 ); GO:0030056 hemidesmosome ( 1.43558771218953e-19 ); GO:0031088 platelet dense granule membrane ( 2.68470245087577e-18 ); GO:0031436 BRCA1-BARD1 complex ( 1.29872512424039e-17 ); GO:0042382 paraspeckles ( 4.55048731461342e-16 ); GO:0009378 four-way junction helicase activity ( 4.11042587701609e-15 ); GO:0043047 single-stranded telomeric DNA binding ( 4.38960996284535e-15 ); GO:0046578 regulation of Ras protein signal transduction ( 8.72153528439934e-14 ); GO:0000724 double-strand break repair via homologous recombination ( 2.02269698582742e-13 ); GO:0000725 recombinational repair ( 4.2925175702107e-13 ); GO:0046834 lipid phosphorylation ( 1.06335831361759e-11 ); GO:0005871 kinesin complex ( 2.00351475231391e-11 ); GO:0015923 mannosidase activity ( 9.64245879063134e-11 ); GO:0016879 ligase activity, forming carbon-nitrogen bonds ( 2.48660202437836e-09 ); GO:0008565 protein transporter activity ( 8.87131591921154e-09 ); GO:0007286 spermatid development ( 5.91324975023301e-08 ); GO:0043241 protein complex disassembly ( 1.30319773059641e-06 ); GO:0043624 cellular protein complex disassembly ( 4.1409979360917e-06 ); GO:0044419 interspecies interaction between organisms ( 5.44917358044676e-06 ); GO:0031109 microtubule polymerization or depolymerization ( 1.41923651087223e-05 ); GO:0000930 gamma-tubulin complex ( 4.75036496523854e-05 ); GO:0005942 phosphoinositide 3-kinase complex ( 0.00126910184696204 ); GO:0005667 transcription factor complex ( 0.00152609489913708 ); GO:0016788 hydrolase activity, acting on ester bonds ( 0.0018564249342045 ); GO:0046777 protein amino acid autophosphorylation ( 0.00218049228580985 ); GO:0007346 regulation of mitotic cell cycle ( 0.00698700873892904 ); GO:0048193 Golgi vesicle transport ( 0.00868080801108015 ); GO:0016567 protein ubiquitination ( 1.42720507668155e-62 ); GO:0008092 cytoskeletal protein binding ( 2.36448906753963e-62 ); GO:0034623 cellular macromolecular complex disassembly ( 5.47788424335496e-52 ); ----------------GO-------------- GO:0005622 intracellular ( 1.95834713120979e-53 ); GO:0005634 nucleus ( 7.32534912514548e-50 ); GO:0044424 intracellular part ( 1.02764755659175e-46 ); GO:0034960 cellular biopolymer metabolic process ( 1.8488743588602e-40 ); GO:0043283 biopolymer metabolic process ( 7.42674933350889e-40 ); GO:0043229 intracellular organelle ( 5.21194495480305e-39 ); GO:0043226 organelle ( 6.24345501006166e-39 ); GO:0044260 cellular macromolecule metabolic process ( 2.09763046856354e-38 ); GO:0043170 macromolecule metabolic process ( 4.76328162527727e-37 ); GO:0043227 membrane-bounded organelle ( 7.49028428120011e-37 ); GO:0043231 intracellular membrane-bounded organelle ( 1.17720317894028e-36 ); GO:0005488 binding ( 7.89366620595222e-31 ); GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 9.57106756215615e-31 ); GO:0003676 nucleic acid binding ( 1.04669794252127e-30 ); GO:0044238 primary metabolic process ( 1.82466054368784e-25 ); GO:0016070 RNA metabolic process ( 4.36149679273706e-23 ); GO:0000166 nucleotide binding ( 5.06265350948568e-23 ); GO:0044237 cellular metabolic process ( 7.26148027334125e-23 ); GO:0005524 ATP binding ( 1.85829886619656e-22 ); GO:0032559 adenyl ribonucleotide binding ( 2.54292753574687e-22 ); GO:0044428 nuclear part ( 5.44851297393965e-22 ); GO:0030554 adenyl nucleotide binding ( 1.10614488672176e-21 ); GO:0015630 microtubule cytoskeleton ( 2.45591045298981e-21 ); GO:0005815 microtubule organizing center ( 3.28022897287666e-20 ); GO:0032553 ribonucleotide binding ( 5.13866607904546e-20 ); GO:0032555 purine ribonucleotide binding ( 5.13866607904546e-20 ); GO:0005813 centrosome ( 5.53578760304676e-20 ); GO:0010467 gene expression ( 1.84795117853113e-19 ); GO:0017076 purine nucleotide binding ( 1.89238042190409e-19 ); GO:0008152 metabolic process ( 2.09976648205406e-19 ); GO:0008270 zinc ion binding ( 8.16434963383593e-19 ); GO:0006974 response to DNA damage stimulus ( 2.89239098198744e-18 ); GO:0031981 nuclear lumen ( 1.19060135353482e-17 ); GO:0005654 nucleoplasm ( 1.60140933236976e-17 ); GO:0044422 organelle part ( 1.8339696331489e-17 ); GO:0044446 intracellular organelle part ( 2.08304202754317e-17 ); GO:0003677 DNA binding ( 7.18978556829222e-17 ); GO:0005515 protein binding ( 1.3780109138261e-16 ); GO:0006281 DNA repair ( 2.28796729061196e-16 ); GO:0034984 cellular response to DNA damage stimulus ( 1.49236605650227e-15 ); GO:0009987 cellular process ( 1.70878839851706e-15 ); GO:0003674 molecular_function ( 2.35927702800966e-15 ); GO:0044464 cell part ( 5.59865497857238e-15 ); GO:0005623 cell ( 5.80950716245636e-15 ); GO:0070013 intracellular organelle lumen ( 7.18252628134231e-15 ); GO:0034961 cellular biopolymer biosynthetic process ( 9.72391153805682e-15 ); GO:0043284 biopolymer biosynthetic process ( 9.72391153805682e-15 ); GO:0051301 cell division ( 1.21662496740011e-14 ); GO:0006350 transcription ( 1.66876811726808e-14 ); GO:0033554 cellular response to stress ( 2.49157947590545e-14 ); GO:0031974 membrane-enclosed lumen ( 3.11292130064292e-14 ); GO:0003723 RNA binding ( 3.7942043960943e-14 ); GO:0043233 organelle lumen ( 4.10976389090599e-14 ); GO:0009059 macromolecule biosynthetic process ( 4.2005767922508e-14 ); GO:0034645 cellular macromolecule biosynthetic process ( 5.1804688179185e-14 ); GO:0005737 cytoplasm ( 5.36047666288218e-14 ); GO:0007049 cell cycle ( 1.22570722210483e-13 ); GO:0046914 transition metal ion binding ( 2.38030988116051e-13 ); GO:0006396 RNA processing ( 2.95932664587492e-13 ); GO:0006259 DNA metabolic process ( 3.41258621624897e-13 ); GO:0006511 ubiquitin-dependent protein catabolic process ( 9.0035374918952e-13 ); GO:0019941 modification-dependent protein catabolic process ( 1.01316296255834e-12 ); GO:0043632 modification-dependent macromolecule catabolic process ( 1.01316296255834e-12 ); GO:0051603 proteolysis involved in cellular protein catabolic process ( 1.01316296255834e-12 ); GO:0051716 cellular response to stimulus ( 1.09477774792877e-12 ); GO:0034962 cellular biopolymer catabolic process ( 1.28127863975981e-12 ); GO:0044257 cellular protein catabolic process ( 1.28127863975981e-12 ); GO:0004386 helicase activity ( 1.58686961152605e-12 ); GO:0004674 protein serine/threonine kinase activity ( 1.78464478005032e-12 ); GO:0043228 non-membrane-bounded organelle ( 2.64955637280756e-12 ); GO:0043232 intracellular non-membrane-bounded organelle ( 2.64955637280756e-12 ); GO:0060255 regulation of macromolecule metabolic process ( 2.7171610645688e-12 ); GO:0032774 RNA biosynthetic process ( 2.90630721390705e-12 ); GO:0017111 nucleoside-triphosphatase activity ( 3.05126025839487e-12 ); GO:0022403 cell cycle phase ( 3.26130079771107e-12 ); GO:0000279 M phase ( 3.34683285641521e-12 ); GO:0010556 regulation of macromolecule biosynthetic process ( 3.58569082330954e-12 ); GO:0006351 transcription, DNA-dependent ( 3.86590781592367e-12 ); GO:0030163 protein catabolic process ( 3.88281706015398e-12 ); GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 4.35703098596193e-12 ); GO:0045449 regulation of transcription ( 5.58872643656608e-12 ); GO:0010468 regulation of gene expression ( 9.25730007773328e-12 ); GO:0000087 M phase of mitotic cell cycle ( 1.21301527466369e-11 ); GO:0051252 regulation of RNA metabolic process ( 1.31016548528117e-11 ); GO:0043285 biopolymer catabolic process ( 1.33841648526861e-11 ); GO:0016462 pyrophosphatase activity ( 1.47571164537132e-11 ); GO:0016604 nuclear body ( 1.53485556166108e-11 ); GO:0005694 chromosome ( 1.72334440949154e-11 ); GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ( 1.96310151546022e-11 ); GO:0006996 organelle organization ( 2.06197323732549e-11 ); GO:0000280 nuclear division ( 2.3138607307141e-11 ); GO:0007067 mitosis ( 2.3138607307141e-11 ); GO:0048285 organelle fission ( 2.52608557496938e-11 ); GO:0016817 hydrolase activity, acting on acid anhydrides ( 2.60453315604448e-11 ); GO:0006355 regulation of transcription, DNA-dependent ( 2.78009850179651e-11 ); GO:0008380 RNA splicing ( 2.97982436557558e-11 ); GO:0033036 macromolecule localization ( 3.2156391769331e-11 ); GO:0044451 nucleoplasm part ( 3.54833125709913e-11 ); GO:0031323 regulation of cellular metabolic process ( 4.93529790020498e-11 ); GO:0016071 mRNA metabolic process ( 5.72443234585113e-11 ); GO:0000278 mitotic cell cycle ( 6.08101468361678e-11 ); GO:0022402 cell cycle process ( 6.14398377504534e-11 ); GO:0031326 regulation of cellular biosynthetic process ( 7.57021943691972e-11 ); GO:0009889 regulation of biosynthetic process ( 7.7151831476133e-11 ); GO:0030695 GTPase regulator activity ( 2.10674494596867e-10 ); GO:0046907 intracellular transport ( 2.32374646783933e-10 ); GO:0004672 protein kinase activity ( 3.15985344632788e-10 ); GO:0019222 regulation of metabolic process ( 3.30754230014155e-10 ); GO:0006397 mRNA processing ( 4.65570335006245e-10 ); GO:0016772 transferase activity, transferring phosphorus-containing groups ( 5.0383108751501e-10 ); GO:0016607 nuclear speck ( 6.65455814053353e-10 ); GO:0005819 spindle ( 8.03434721874345e-10 ); GO:0051641 cellular localization ( 1.31019690486544e-09 ); GO:0008104 protein localization ( 1.36743357326779e-09 ); GO:0015031 protein transport ( 1.37554664327516e-09 ); GO:0044265 cellular macromolecule catabolic process ( 1.45272714528856e-09 ); GO:0045184 establishment of protein localization ( 1.61962836568055e-09 ); GO:0043412 biopolymer modification ( 1.77400736543128e-09 ); GO:0016773 phosphotransferase activity, alcohol group as acceptor ( 2.0735780446759e-09 ); GO:0003824 catalytic activity ( 2.59039626063196e-09 ); GO:0016301 kinase activity ( 2.96133761700789e-09 ); GO:0008150 biological_process ( 3.10259551367731e-09 ); GO:0051649 establishment of localization in cell ( 3.94521050709656e-09 ); GO:0009057 macromolecule catabolic process ( 4.93911908590032e-09 ); GO:0005856 cytoskeleton ( 6.00008417638911e-09 ); GO:0006464 protein modification process ( 6.15643093868859e-09 ); GO:0006468 protein amino acid phosphorylation ( 6.83945738655467e-09 ); GO:0044430 cytoskeletal part ( 1.33362243073885e-08 ); GO:0000151 ubiquitin ligase complex ( 1.54567064629843e-08 ); GO:0016740 transferase activity ( 1.56153157352331e-08 ); GO:0016310 phosphorylation ( 1.79275412255378e-08 ); GO:0046872 metal ion binding ( 2.11473494590253e-08 ); GO:0043687 post-translational protein modification ( 3.10841583406933e-08 ); GO:0016887 ATPase activity ( 3.27501691667908e-08 ); GO:0044267 cellular protein metabolic process ( 3.32688806168771e-08 ); GO:0005096 GTPase activator activity ( 3.51787681637356e-08 ); GO:0006793 phosphorus metabolic process ( 3.6678754311008e-08 ); GO:0006796 phosphate metabolic process ( 3.6678754311008e-08 ); GO:0016043 cellular component organization ( 4.6188550953386e-08 ); GO:0019538 protein metabolic process ( 5.46193667981623e-08 ); GO:0008026 ATP-dependent helicase activity ( 5.77607391610302e-08 ); GO:0070035 purine NTP-dependent helicase activity ( 5.77607391610302e-08 ); GO:0019899 enzyme binding ( 7.14271425232449e-08 ); GO:0007017 microtubule-based process ( 8.58477710944845e-08 ); GO:0051276 chromosome organization ( 9.98704691996834e-08 ); GO:0044249 cellular biosynthetic process ( 1.20506616430455e-07 ); GO:0009058 biosynthetic process ( 1.4465395639253e-07 ); GO:0004221 ubiquitin thiolesterase activity ( 1.44908305389568e-07 ); GO:0043167 ion binding ( 1.55949262014001e-07 ); GO:0000793 condensed chromosome ( 4.66452607373661e-07 ); GO:0007059 chromosome segregation ( 4.76469344112907e-07 ); GO:0044427 chromosomal part ( 8.6024985089859e-07 ); GO:0043234 protein complex ( 1.03030614708344e-06 ); GO:0000226 microtubule cytoskeleton organization ( 1.28999519446177e-06 ); GO:0042623 ATPase activity, coupled ( 1.33111708575847e-06 ); GO:0005794 Golgi apparatus ( 1.41430613765349e-06 ); GO:0008047 enzyme activator activity ( 1.49655110101934e-06 ); GO:0006310 DNA recombination ( 1.68081230452582e-06 ); GO:0006302 double-strand break repair ( 2.7742506381529e-06 ); GO:0032991 macromolecular complex ( 2.86716348498798e-06 ); GO:0006886 intracellular protein transport ( 3.1733414590772e-06 ); GO:0000075 cell cycle checkpoint ( 4.43611496594585e-06 ); GO:0006260 DNA replication ( 4.94262850330902e-06 ); GO:0000375 RNA splicing, via transesterification reactions ( 5.52007918830702e-06 ); GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile ( 5.52007918830702e-06 ); GO:0000398 nuclear mRNA splicing, via spliceosome ( 5.52007918830702e-06 ); GO:0016790 thiolester hydrolase activity ( 5.781859381284e-06 ); GO:0043169 cation binding ( 6.21586847129422e-06 ); GO:0034613 cellular protein localization ( 7.22283498647512e-06 ); GO:0044248 cellular catabolic process ( 1.20843810992748e-05 ); GO:0005730 nucleolus ( 1.56525098617631e-05 ); GO:0005083 small GTPase regulator activity ( 2.3836473612673e-05 ); GO:0005874 microtubule ( 2.54112004273213e-05 ); GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 3.07479875511068e-05 ); GO:0007094 mitotic cell cycle spindle assembly checkpoint ( 3.33027650231735e-05 ); GO:0031577 spindle checkpoint ( 3.33027650231735e-05 ); GO:0050794 regulation of cellular process ( 4.49247959931558e-05 ); GO:0031461 cullin-RING ubiquitin ligase complex ( 5.12127666422882e-05 ); GO:0031324 negative regulation of cellular metabolic process ( 5.38098036314407e-05 ); GO:0010605 negative regulation of macromolecule metabolic process ( 6.12057131253371e-05 ); GO:0016787 hydrolase activity ( 6.61360673776728e-05 ); GO:0031119 tRNA pseudouridine synthesis ( 6.65332006347272e-05 ); GO:0008234 cysteine-type peptidase activity ( 6.76740839196375e-05 ); GO:0000228 nuclear chromosome ( 6.9430271045981e-05 ); GO:0005876 spindle microtubule ( 8.38026046416749e-05 ); GO:0031023 microtubule organizing center organization ( 9.97469380136552e-05 ); GO:0051297 centrosome organization ( 9.97469380136552e-05 ); GO:0005099 Ras GTPase activator activity ( 0.000102169149293558 ); GO:0051018 protein kinase A binding ( 0.000107822612003001 ); GO:0006508 proteolysis ( 0.000116594593433929 ); GO:0007093 mitotic cell cycle checkpoint ( 0.000128472525655409 ); GO:0015631 tubulin binding ( 0.000137067809909272 ); GO:0000775 chromosome, centromeric region ( 0.000143790107199141 ); GO:0016591 DNA-directed RNA polymerase II, holoenzyme ( 0.000143790107199141 ); GO:0000776 kinetochore ( 0.000151674936192512 ); GO:0048523 negative regulation of cellular process ( 0.000154663190835004 ); GO:0043087 regulation of GTPase activity ( 0.000173807984469668 ); GO:0003777 microtubule motor activity ( 0.000182412443935262 ); GO:0051020 GTPase binding ( 0.000182412443935262 ); GO:0050789 regulation of biological process ( 0.000182580891328527 ); GO:0010558 negative regulation of macromolecule biosynthetic process ( 0.000185923260444854 ); GO:0005798 Golgi-associated vesicle ( 0.000192897226490938 ); GO:0016563 transcription activator activity ( 0.000197356139052344 ); GO:0009056 catabolic process ( 0.000205666100743203 ); GO:0009892 negative regulation of metabolic process ( 0.000245625370329963 ); GO:0009890 negative regulation of biosynthetic process ( 0.000264794149269259 ); GO:0030234 enzyme regulator activity ( 0.000282169911017565 ); GO:0007131 reciprocal meiotic recombination ( 0.000304426394241181 ); GO:0003684 damaged DNA binding ( 0.000308348674481576 ); GO:0008094 DNA-dependent ATPase activity ( 0.000308348674481576 ); GO:0007243 protein kinase cascade ( 0.000309544346888349 ); GO:0044450 microtubule organizing center part ( 0.000356915943185314 ); GO:0031327 negative regulation of cellular biosynthetic process ( 0.000360305072080511 ); GO:0005575 cellular_component ( 0.000391128222531816 ); GO:0000723 telomere maintenance ( 0.000410189651249667 ); GO:0010212 response to ionizing radiation ( 0.000410189651249667 ); GO:0032200 telomere organization ( 0.000410189651249667 ); GO:0004843 ubiquitin-specific protease activity ( 0.000419450947350987 ); GO:0042770 DNA damage response, signal transduction ( 0.000464119254222728 ); GO:0016568 chromatin modification ( 0.000471701518998181 ); GO:0005875 microtubule associated complex ( 0.000530168015938022 ); GO:0050657 nucleic acid transport ( 0.000586209664707595 ); GO:0050658 RNA transport ( 0.000586209664707595 ); GO:0051236 establishment of RNA localization ( 0.000586209664707595 ); GO:0000779 condensed chromosome, centromeric region ( 0.000625566247801108 ); GO:0051056 regulation of small GTPase mediated signal transduction ( 0.000632947545295814 ); GO:0019783 small conjugating protein-specific protease activity ( 0.000633045347256913 ); GO:0031625 ubiquitin protein ligase binding ( 0.000633045347256913 ); GO:0005681 spliceosome ( 0.000634046529003444 ); GO:0043566 structure-specific DNA binding ( 0.00065625018914116 ); GO:0007242 intracellular signaling cascade ( 0.000690328997579043 ); GO:0016481 negative regulation of transcription ( 0.00072581592092987 ); GO:0000019 regulation of mitotic recombination ( 0.000737239755222687 ); GO:0048478 replication fork protection ( 0.000737239755222687 ); GO:0000940 outer kinetochore of condensed chromosome ( 0.000737239755222687 ); GO:0000405 bubble DNA binding ( 0.000737239755222687 ); GO:0006403 RNA localization ( 0.000792514546085821 ); GO:0016881 acid-amino acid ligase activity ( 0.00084050978384992 ); GO:0000796 condensin complex ( 0.00085937645336644 ); GO:0000922 spindle pole ( 0.000860329563291351 ); GO:0048519 negative regulation of biological process ( 0.000882090118022632 ); GO:0005097 Rab GTPase activator activity ( 0.000916700485733305 ); GO:0007010 cytoskeleton organization ( 0.000930257610187532 ); GO:0019787 small conjugating protein ligase activity ( 0.000986240235183624 ); GO:0016303 1-phosphatidylinositol-3-kinase activity ( 0.00102534729141427 ); GO:0016363 nuclear matrix ( 0.00111557075440377 ); GO:0000819 sister chromatid segregation ( 0.00126701349288336 ); GO:0000794 condensed nuclear chromosome ( 0.00126701349288336 ); GO:0044431 Golgi apparatus part ( 0.0015021627776372 ); GO:0000781 chromosome, telomeric region ( 0.00155193333005254 ); GO:0010629 negative regulation of gene expression ( 0.00157475537843581 ); GO:0000777 condensed chromosome kinetochore ( 0.00158471222735257 ); GO:0003678 DNA helicase activity ( 0.00158471222735257 ); GO:0032318 regulation of Ras GTPase activity ( 0.00159511831342822 ); GO:0035004 phosphoinositide 3-kinase activity ( 0.00174023790600839 ); GO:0016874 ligase activity ( 0.0017810417245539 ); GO:0007018 microtubule-based movement ( 0.00182220101530343 ); GO:0000217 DNA secondary structure binding ( 0.00186144824185103 ); GO:0034399 nuclear periphery ( 0.00193705104598489 ); GO:0006913 nucleocytoplasmic transport ( 0.00198731618253849 ); GO:0018209 peptidyl-serine modification ( 0.00203266751060112 ); GO:0051052 regulation of DNA metabolic process ( 0.00217691908122228 ); GO:0008017 microtubule binding ( 0.00218122630586258 ); GO:0006605 protein targeting ( 0.00219729353564163 ); GO:0065007 biological regulation ( 0.00229791405901551 ); GO:0051169 nuclear transport ( 0.00238026557265849 ); GO:0004842 ubiquitin-protein ligase activity ( 0.0024172802003974 ); GO:0004003 ATP-dependent DNA helicase activity ( 0.00245802815374158 ); GO:0035091 phosphoinositide binding ( 0.00248234540709165 ); GO:0044444 cytoplasmic part ( 0.00252415428094046 ); GO:0016564 transcription repressor activity ( 0.00254597698500492 ); GO:0044454 nuclear chromosome part ( 0.002600839085917 ); GO:0032313 regulation of Rab GTPase activity ( 0.00261908201232959 ); GO:0032482 Rab protein signal transduction ( 0.00261908201232959 ); GO:0032483 regulation of Rab protein signal transduction ( 0.00261908201232959 ); GO:0000077 DNA damage checkpoint ( 0.00262318215442749 ); GO:0000245 spliceosome assembly ( 0.00262318215442749 ); GO:0000287 magnesium ion binding ( 0.0027491105826597 ); GO:0045898 regulation of transcriptional preinitiation complex assembly ( 0.00274935941898657 ); GO:0005828 kinetochore microtubule ( 0.00274935941898657 ); GO:0005955 calcineurin complex ( 0.00274935941898657 ); GO:0003918 DNA topoisomerase (ATP-hydrolyzing) activity ( 0.00274935941898657 ); GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity ( 0.00274935941898657 ); GO:0010165 response to X-ray ( 0.00276232694276326 ); GO:0042826 histone deacetylase binding ( 0.00276232694276326 ); GO:0007098 centrosome cycle ( 0.00278853704809326 ); GO:0007050 cell cycle arrest ( 0.00299444998739493 ); GO:0051325 interphase ( 0.00299444998739493 ); GO:0003690 double-stranded DNA binding ( 0.00319862003275693 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00323069889256885 ); GO:0018105 peptidyl-serine phosphorylation ( 0.00326107193676862 ); GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport ( 0.00337073868560085 ); GO:0006312 mitotic recombination ( 0.00345687190147139 ); GO:0051298 centrosome duplication ( 0.00345687190147139 ); GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ( 0.00345687190147139 ); GO:0008318 protein prenyltransferase activity ( 0.00345687190147139 ); GO:0006366 transcription from RNA polymerase II promoter ( 0.0034908534955765 ); GO:0009966 regulation of signal transduction ( 0.00355214688332258 ); GO:0043933 macromolecular complex subunit organization ( 0.003611366669944 ); GO:0030705 cytoskeleton-dependent intracellular transport ( 0.00362372672983845 ); GO:0000152 nuclear ubiquitin ligase complex ( 0.00386628289851145 ); GO:0034621 cellular macromolecular complex subunit organization ( 0.00388297937863627 ); GO:0032446 protein modification by small protein conjugation ( 0.00389883412086555 ); GO:0051329 interphase of mitotic cell cycle ( 0.00408163974924241 ); GO:0006400 tRNA modification ( 0.00415719237937275 ); GO:0007026 negative regulation of microtubule depolymerization ( 0.00415719237937275 ); GO:0031114 regulation of microtubule depolymerization ( 0.00415719237937275 ); GO:0000070 mitotic sister chromatid segregation ( 0.00419884297186915 ); GO:0048471 perinuclear region of cytoplasm ( 0.00424091436427446 ); GO:0060249 anatomical structure homeostasis ( 0.00434382692920028 ); GO:0007126 meiosis ( 0.00437245164274082 ); GO:0051321 meiotic cell cycle ( 0.00437245164274082 ); GO:0051327 M phase of meiotic cell cycle ( 0.00437245164274082 ); GO:0006261 DNA-dependent DNA replication ( 0.00464488515713055 ); GO:0051028 mRNA transport ( 0.00464488515713055 ); GO:0016192 vesicle-mediated transport ( 0.00479101308328781 ); GO:0030528 transcription regulator activity ( 0.00484172583795543 ); GO:0003713 transcription coactivator activity ( 0.00488830289207356 ); GO:0051640 organelle localization ( 0.00505375879640873 ); GO:0005793 ER-Golgi intermediate compartment ( 0.00505595412928649 ); GO:0000018 regulation of DNA recombination ( 0.00522399865210997 ); GO:0000784 nuclear chromosome, telomeric region ( 0.00522399865210997 ); GO:0003682 chromatin binding ( 0.00535946806525681 ); GO:0003724 RNA helicase activity ( 0.00544885755232231 ); GO:0004402 histone acetyltransferase activity ( 0.00544885755232231 ); GO:0004468 lysine N-acetyltransferase activity ( 0.00544885755232231 ); GO:0031252 cell leading edge ( 0.00558628818667016 ); GO:0005080 protein kinase C binding ( 0.00577925033153965 ); GO:0015924 mannosyl-oligosaccharide mannosidase activity ( 0.00577925033153965 ); GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade ( 0.00588467596748649 ); GO:0007019 microtubule depolymerization ( 0.00599028037945897 ); GO:0031111 negative regulation of microtubule polymerization or depolymerization ( 0.00599028037945897 ); GO:0046854 phosphoinositide phosphorylation ( 0.00599028037945897 ); GO:0048284 organelle fusion ( 0.00599028037945897 ); GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator ( 0.00641040755576003 ); GO:0010225 response to UV-C ( 0.00641040755576003 ); GO:0042772 DNA damage response, signal transduction resulting in transcription ( 0.00641040755576003 ); GO:0051123 transcriptional preinitiation complex assembly ( 0.00641040755576003 ); GO:0004652 polynucleotide adenylyltransferase activity ( 0.00641040755576003 ); GO:0045502 dynein binding ( 0.00641040755576003 ); GO:0031570 DNA integrity checkpoint ( 0.00641710012254941 ); GO:0051053 negative regulation of DNA metabolic process ( 0.00641710012254941 ); GO:0000139 Golgi membrane ( 0.00669136489592811 ); GO:0007249 I-kappaB kinase/NF-kappaB cascade ( 0.00675965484273185 ); GO:0030330 DNA damage response, signal transduction by p53 class mediator ( 0.0069004679403214 ); GO:0005635 nuclear envelope ( 0.00696286676531309 ); GO:0008134 transcription factor binding ( 0.00747236942305683 ); GO:0017016 Ras GTPase binding ( 0.00767893273505464 ); GO:0010627 regulation of protein kinase cascade ( 0.00774696238728546 ); GO:0001675 acrosome formation ( 0.00816505343604369 ); GO:0007079 mitotic chromosome movement towards spindle pole ( 0.00816505343604369 ); GO:0031297 replication fork processing ( 0.00816505343604369 ); GO:0040016 embryonic cleavage ( 0.00816505343604369 ); GO:0045899 positive regulation of transcriptional preinitiation complex assembly ( 0.00816505343604369 ); GO:0050858 negative regulation of antigen receptor-mediated signaling pathway ( 0.00816505343604369 ); GO:0050860 negative regulation of T cell receptor signaling pathway ( 0.00816505343604369 ); GO:0051300 spindle pole body organization ( 0.00816505343604369 ); GO:0060009 Sertoli cell development ( 0.00816505343604369 ); GO:0005968 Rab-protein geranylgeranyltransferase complex ( 0.00816505343604369 ); GO:0030056 hemidesmosome ( 0.00816505343604369 ); GO:0031088 platelet dense granule membrane ( 0.00816505343604369 ); GO:0031436 BRCA1-BARD1 complex ( 0.00816505343604369 ); GO:0042382 paraspeckles ( 0.00816505343604369 ); GO:0009378 four-way junction helicase activity ( 0.00816505343604369 ); GO:0043047 single-stranded telomeric DNA binding ( 0.00816505343604369 ); GO:0046578 regulation of Ras protein signal transduction ( 0.00821128610935454 ); GO:0000724 double-strand break repair via homologous recombination ( 0.00832513230346839 ); GO:0000725 recombinational repair ( 0.00832513230346839 ); GO:0046834 lipid phosphorylation ( 0.00832513230346839 ); GO:0005871 kinesin complex ( 0.00832513230346839 ); GO:0015923 mannosidase activity ( 0.00832513230346839 ); GO:0016879 ligase activity, forming carbon-nitrogen bonds ( 0.00854322200243013 ); GO:0008565 protein transporter activity ( 0.00855214405424902 ); GO:0007286 spermatid development ( 0.00858273111431678 ); GO:0043241 protein complex disassembly ( 0.00875833777765744 ); GO:0043624 cellular protein complex disassembly ( 0.00875833777765744 ); GO:0044419 interspecies interaction between organisms ( 0.00888556502170458 ); GO:0031109 microtubule polymerization or depolymerization ( 0.00893419820752822 ); GO:0000930 gamma-tubulin complex ( 0.00894851902495657 ); GO:0005942 phosphoinositide 3-kinase complex ( 0.00894851902495657 ); GO:0005667 transcription factor complex ( 0.00905562596364231 ); GO:0016788 hydrolase activity, acting on ester bonds ( 0.00909381276298186 ); GO:0046777 protein amino acid autophosphorylation ( 0.00923936066541298 ); GO:0007346 regulation of mitotic cell cycle ( 0.00962017058151154 ); GO:0048193 Golgi vesicle transport ( 0.00974635092670731 ); GO:0016567 protein ubiquitination ( 0.00979295868903289 ); GO:0008092 cytoskeletal protein binding ( 0.00980077029875042 ); GO:0034623 cellular macromolecular complex disassembly ( 0.00995237599630461 ); ----------------KEGG-------------- hsa04120 Ubiquitin mediated proteolysis ( 4.62323272084547e-06 ); hsa03022 Basal transcription factors ( 0.00205520100900888 ); hsa04210 Apoptosis ( 0.00515229670887518 ); hsa05210 Colorectal cancer ( 0.00785138659020072 ); hsa04150 mTOR signaling pathway ( 0.0082367146011368 ); hsa04070 Phosphatidylinositol signaling system ( 0.018028392484555 ); hsa05211 Renal cell carcinoma ( 0.0199562592831228 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0203013661107975 ); hsa05223 Non-small cell lung cancer ( 0.0214363862985309 ); hsa05222 Small cell lung cancer ( 0.0216695518635799 ); hsa04110 Cell cycle ( 0.0233043784259323 ); hsa03450 Non-homologous end-joining ( 0.0244703414550216 ); hsa04662 B cell receptor signaling pathway ( 0.0302925800978809 ); hsa05220 Chronic myeloid leukemia ( 0.0328511940561736 ); hsa03440 Homologous recombination ( 0.0360694576381244 ); hsa05213 Endometrial cancer ( 0.0418092412304966 ); hsa04660 T cell receptor signaling pathway ( 0.0426705582477957 ); ----------------CARTA-------------- g2pathway ( 0.000410189651249667 ); gspathway ( 0.00816505343604369 ); tnfr2pathway ( 0.00816505343604369 ); tollpathway ( 0.0155085177109938 ); eif4pathway ( 0.017546371684831 ); ghpathway ( 0.0185097408671095 ); g1pathway ( 0.0189162553484671 ); salmonellapathway ( 0.0189162553484671 ); fmlppathway ( 0.0282995906400911 ); p38mapkpathway ( 0.0322833767799584 ); par1pathway ( 0.0404213599149842 ); nos1pathway ( 0.0408866256518193 ); integrinpathway ( 0.043052407882356 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 3.02316306174459e-247 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 1.16667581260376e-129 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 7.52659685293498e-105 ); TDP-43_iCLIP_(Tollervey_2011) ( 1.29595077879072e-91 ); ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 6.09156564246292e-87 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 1.7080092415521e-66 ); TIAL1_iCLIP_(Wang_2010) ( 8.23216358381015e-48 ); QKI_PAR-CLIP_(Hafner_2010) ( 3.79186798138539e-40 ); PUM2_PAR-CLIP_(Hafner_2010) ( 1.73567083302904e-32 ); hnRNPC_iCLIP_(Koenig_2010) ( 5.72744547007345e-20 ); TIA1_iCLIP_(Wang_2010) ( 5.74748860593362e-13 ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_ALL ( 5.82053386303399e-40 ); ARE_C5 ( 1.45257329526863e-33 ); ARE_C4 ( 7.21301510305443e-05 ); ARE_C3 ( 0.000594690345134697 ); ============================ group15 ========================= ----------------C2-------------- REACTOME_NCAM1_INTERACTIONS ( 8.62480275805637e-05 ); REACTOME_GPCR_LIGAND_BINDING ( 0.000190819045613125 ); KEGG_BASAL_CELL_CARCINOMA ( 0.00021651774375023 ); KEGG_ECM_RECEPTOR_INTERACTION ( 0.000524732614107271 ); REACTOME_CLASS_B2_SECRETIN_FAMILY_RECEPTORS ( 0.000690212290006888 ); KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION ( 0.00129292499232006 ); REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH ( 0.00210630113118491 ); BIOCARTA_PLATELETAPP_PATHWAY ( 0.00298743255178353 ); REACTOME_SIGNAL_ATTENUATION ( 0.00504386451831126 ); REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS ( 0.00540092727401403 ); BIOCARTA_VITCB_PATHWAY ( 0.00744706219239955 ); KEGG_HEDGEHOG_SIGNALING_PATHWAY ( 0.00971553829500979 ); ----------------C3-------------- CAGGTG_V$E12_Q6 ( 8.08465296951071e-06 ); GGGAGGRR_V$MAZ_Q6 ( 7.8977863745478e-05 ); V$NRSF_01 ( 0.000183232786986874 ); V$TFIII_Q6 ( 0.000538265118762829 ); CCANNAGRKGGC_UNKNOWN ( 0.000690212290006888 ); GGGTGGRR_V$PAX4_03 ( 0.000716969450673125 ); GCANCTGNY_V$MYOD_Q6 ( 0.00128599350388383 ); GGGGCCC,MIR-296 ( 0.00181762806845668 ); CTGCAGY_UNKNOWN ( 0.00443519452683727 ); V$LMO2COM_01 ( 0.00556056234714636 ); V$AR_01 ( 0.00587084317316285 ); CAGNWMCNNNGAC_UNKNOWN ( 0.00604028593400901 ); V$AP2ALPHA_01 ( 0.00820525021253403 ); ----------------C4-------------- module_60 ( 2.29702495850305e-07 ); module_55 ( 3.07033627416543e-07 ); module_88 ( 6.65483950937505e-07 ); module_100 ( 2.76961583882598e-06 ); module_137 ( 2.96660156946777e-06 ); module_66 ( 4.45234655878824e-06 ); module_190 ( 8.88487576674733e-06 ); module_474 ( 8.91990317758825e-06 ); module_23 ( 3.70582567670646e-05 ); module_38 ( 4.29148121166591e-05 ); module_41 ( 5.04034306948531e-05 ); module_379 ( 0.000158559248000845 ); module_104 ( 0.000289118688829713 ); module_242 ( 0.000389650249822376 ); MORF_WNT1 ( 0.000448735124091765 ); module_24 ( 0.000474570894636415 ); module_501 ( 0.000563013655438204 ); MORF_LCAT ( 0.00081991246118548 ); module_181 ( 0.000841589995734347 ); module_99 ( 0.000896539074236494 ); module_274 ( 0.00119307150400916 ); module_174 ( 0.00147677497707454 ); module_12 ( 0.00225162272030119 ); module_316 ( 0.00240793838402454 ); GNF2_TTN ( 0.00282921779486201 ); module_1 ( 0.00325584728495939 ); module_13 ( 0.00353201768965371 ); module_11 ( 0.00373479767205739 ); module_47 ( 0.00434441151480641 ); module_122 ( 0.0045112099800126 ); module_154 ( 0.00851456389905284 ); MORF_TNFRSF25 ( 0.00891478383143505 ); ----------------C5-------------- SYSTEM_DEVELOPMENT ( 1.20874146312981e-05 ); ANATOMICAL_STRUCTURE_DEVELOPMENT ( 1.2737741601108e-05 ); MULTICELLULAR_ORGANISMAL_DEVELOPMENT ( 2.01876548715712e-05 ); AXONOGENESIS ( 6.74129780093751e-05 ); POTASSIUM_CHANNEL_ACTIVITY ( 7.60158315546019e-05 ); POTASSIUM_ION_TRANSPORT ( 9.81717543554564e-05 ); NEURITE_DEVELOPMENT ( 0.000145060455971555 ); ANATOMICAL_STRUCTURE_MORPHOGENESIS ( 0.000167101268476276 ); GLAND_DEVELOPMENT ( 0.000220822928686767 ); NERVOUS_SYSTEM_DEVELOPMENT ( 0.000230006736400077 ); SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.000255768089256412 ); CELLULAR_MORPHOGENESIS_DURING_DIFFERENTIATION ( 0.00026332205489207 ); PLASMA_MEMBRANE_PART ( 0.00029258699378109 ); ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.000296578737569583 ); SUBSTRATE_SPECIFIC_TRANSPORTER_ACTIVITY ( 0.000399017821545776 ); TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.000482409475071834 ); METAL_ION_TRANSPORT ( 0.000525439911234913 ); CATION_CHANNEL_ACTIVITY ( 0.000588764445711385 ); NEURON_DIFFERENTIATION ( 0.000598056083044766 ); NEURON_DEVELOPMENT ( 0.000635588214931367 ); SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY ( 0.000649866533187783 ); ION_CHANNEL_ACTIVITY ( 0.000784523275101251 ); ION_TRANSPORT ( 0.000822677819745478 ); PLASMA_MEMBRANE ( 0.000838252464063026 ); FOCAL_ADHESION ( 0.000838268588656738 ); VOLTAGE_GATED_CHANNEL_ACTIVITY ( 0.00120742354157406 ); ORGAN_DEVELOPMENT ( 0.00125270846683088 ); COLLAGEN ( 0.00129292499232006 ); VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY ( 0.00130199114975198 ); VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY ( 0.00138180774953189 ); METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.0015193796365731 ); GENERATION_OF_NEURONS ( 0.00154201937008571 ); CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00155855056656461 ); MONOVALENT_INORGANIC_CATION_TRANSPORT ( 0.00166246037487698 ); CATION_TRANSPORT ( 0.00166383889203909 ); REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS ( 0.00170519727747271 ); NEUROGENESIS ( 0.00186733241655611 ); CELL_FATE_COMMITMENT ( 0.00204952342470418 ); VOLTAGE_GATED_POTASSIUM_CHANNEL_COMPLEX ( 0.00286181586199106 ); CELL_SUBSTRATE_ADHERENS_JUNCTION ( 0.00298743255178353 ); MEMBRANE_PART ( 0.00315095676189665 ); G_PROTEIN_SIGNALING__ADENYLATE_CYCLASE_INHIBITING_PATHWAY ( 0.00322158472818713 ); INTEGRAL_TO_PLASMA_MEMBRANE ( 0.00413580771223518 ); POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION_AND_BIOGENESIS ( 0.00436785431765054 ); INTRINSIC_TO_PLASMA_MEMBRANE ( 0.00446057372997183 ); REGULATION_OF_AXONOGENESIS ( 0.00504386451831126 ); CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.00519155348740569 ); AXON_GUIDANCE ( 0.00526071390341787 ); CELL_MATRIX_JUNCTION ( 0.00572567275918407 ); TRANSFERASE_ACTIVITY__TRANSFERRING_SULFUR_CONTAINING_GROUPS ( 0.00668094469292409 ); ORGAN_MORPHOGENESIS ( 0.00672878512736896 ); PROTEINACEOUS_EXTRACELLULAR_MATRIX ( 0.0071498477836468 ); MEMBRANE ( 0.00810309160797717 ); EXTRACELLULAR_MATRIX ( 0.00861955903177989 ); EXTRACELLULAR_MATRIX_PART ( 0.00971553829500979 ); ----------------GOSLIM-------------- GO:0005576 extracellular region ( 4.14938538693213e-14 ); GO:0048856 anatomical structure development ( 2.69149844232712e-11 ); GO:0048731 system development ( 5.13931410843501e-10 ); GO:0007275 multicellular organismal development ( 3.16752794728306e-08 ); GO:0048869 cellular developmental process ( 6.88604953983364e-06 ); GO:0005578 proteinaceous extracellular matrix ( 0.000909735730545878 ); GO:0048468 cell development ( 0.00124372125917679 ); GO:0030154 cell differentiation ( 0.00266594127037729 ); GO:0032501 multicellular organismal process ( 0.0026938050909277 ); GO:0048513 organ development ( 0.00290997032417904 ); GO:0031012 extracellular matrix ( 0.00296938699814651 ); GO:0005520 insulin-like growth factor binding ( 0.00315644488685318 ); GO:0007399 nervous system development ( 0.00410354645919316 ); GO:0050767 regulation of neurogenesis ( 0.00632104655082788 ); GO:0009653 anatomical structure morphogenesis ( 0.0084002663665815 ); GO:0060284 regulation of cell development ( 4.14938538693213e-14 ); GO:0051960 regulation of nervous system development ( 2.69149844232712e-11 ); GO:0045664 regulation of neuron differentiation ( 5.13931410843501e-10 ); GO:0044421 extracellular region part ( 3.16752794728306e-08 ); GO:0022008 neurogenesis ( 6.88604953983364e-06 ); GO:0043565 sequence-specific DNA binding ( 0.000909735730545878 ); GO:0048699 generation of neurons ( 0.00124372125917679 ); GO:0015267 channel activity ( 0.00266594127037729 ); GO:0022803 passive transmembrane transporter activity ( 0.0026938050909277 ); GO:0030182 neuron differentiation ( 0.00290997032417904 ); GO:0045666 positive regulation of neuron differentiation ( 0.00296938699814651 ); GO:0022838 substrate specific channel activity ( 0.00315644488685318 ); GO:0005581 collagen ( 0.00410354645919316 ); GO:0032502 developmental process ( 0.00632104655082788 ); GO:0005216 ion channel activity ( 0.0084002663665815 ); GO:0005244 voltage-gated ion channel activity ( 4.14938538693213e-14 ); GO:0022832 voltage-gated channel activity ( 2.69149844232712e-11 ); GO:0031224 intrinsic to membrane ( 5.13931410843501e-10 ); GO:0022836 gated channel activity ( 3.16752794728306e-08 ); GO:0007155 cell adhesion ( 6.88604953983364e-06 ); GO:0022610 biological adhesion ( 0.000909735730545878 ); GO:0044420 extracellular matrix part ( 0.00124372125917679 ); GO:0003700 transcription factor activity ( 0.00266594127037729 ); GO:0022857 transmembrane transporter activity ( 0.0026938050909277 ); GO:0016021 integral to membrane ( 0.00290997032417904 ); GO:0031420 alkali metal ion binding ( 0.00296938699814651 ); GO:0007417 central nervous system development ( 0.00315644488685318 ); GO:0007398 ectoderm development ( 0.00410354645919316 ); GO:0022891 substrate-specific transmembrane transporter activity ( 0.00632104655082788 ); GO:0044425 membrane part ( 0.0084002663665815 ); GO:0004252 serine-type endopeptidase activity ( 4.14938538693213e-14 ); GO:0015075 ion transmembrane transporter activity ( 2.69149844232712e-11 ); GO:0031344 regulation of cell projection organization ( 5.13931410843501e-10 ); GO:0030934 anchoring collagen ( 3.16752794728306e-08 ); GO:0006813 potassium ion transport ( 6.88604953983364e-06 ); GO:0005267 potassium channel activity ( 0.000909735730545878 ); GO:0009887 organ morphogenesis ( 0.00124372125917679 ); GO:0022892 substrate-specific transporter activity ( 0.00266594127037729 ); GO:0000902 cell morphogenesis ( 0.0026938050909277 ); GO:0032989 cellular structure morphogenesis ( 0.00290997032417904 ); GO:0048663 neuron fate commitment ( 0.00296938699814651 ); GO:0031346 positive regulation of cell projection organization ( 0.00315644488685318 ); GO:0031175 neurite development ( 0.00410354645919316 ); GO:0032922 circadian regulation of gene expression ( 0.00632104655082788 ); GO:0019838 growth factor binding ( 0.0084002663665815 ); GO:0008544 epidermis development ( 4.14938538693213e-14 ); GO:0048812 neurite morphogenesis ( 2.69149844232712e-11 ); GO:0005215 transporter activity ( 5.13931410843501e-10 ); GO:0015672 monovalent inorganic cation transport ( 3.16752794728306e-08 ); GO:0005261 cation channel activity ( 6.88604953983364e-06 ); GO:0001558 regulation of cell growth ( 0.000909735730545878 ); GO:0050772 positive regulation of axonogenesis ( 0.00124372125917679 ); GO:0022843 voltage-gated cation channel activity ( 0.00266594127037729 ); GO:0048667 cell morphogenesis involved in neuron differentiation ( 0.0026938050909277 ); GO:0007154 cell communication ( 0.00290997032417904 ); GO:0006811 ion transport ( 0.00296938699814651 ); GO:0010628 positive regulation of gene expression ( 0.00315644488685318 ); GO:0010769 regulation of cell morphogenesis involved in differentiation ( 0.00410354645919316 ); GO:0040008 regulation of growth ( 0.00632104655082788 ); GO:0045941 positive regulation of transcription ( 0.0084002663665815 ); GO:0005201 extracellular matrix structural constituent ( 4.14938538693213e-14 ); GO:0032990 cell part morphogenesis ( 2.69149844232712e-11 ); GO:0048858 cell projection morphogenesis ( 5.13931410843501e-10 ); GO:0010551 regulation of specific transcription from RNA polymerase II promoter ( 3.16752794728306e-08 ); GO:0032569 specific transcription from RNA polymerase II promoter ( 6.88604953983364e-06 ); GO:0016055 Wnt receptor signaling pathway ( 0.000909735730545878 ); GO:0045596 negative regulation of cell differentiation ( 0.00124372125917679 ); GO:0008236 serine-type peptidase activity ( 0.00266594127037729 ); GO:0042063 gliogenesis ( 0.0026938050909277 ); GO:0005886 plasma membrane ( 0.00290997032417904 ); GO:0017171 serine hydrolase activity ( 0.00296938699814651 ); GO:0050768 negative regulation of neurogenesis ( 0.00315644488685318 ); GO:0050793 regulation of developmental process ( 0.00410354645919316 ); GO:0048666 neuron development ( 0.00632104655082788 ); GO:0014014 negative regulation of gliogenesis ( 0.0084002663665815 ); GO:0045686 negative regulation of glial cell differentiation ( 4.14938538693213e-14 ); GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 2.69149844232712e-11 ); GO:0035270 endocrine system development ( 5.13931410843501e-10 ); GO:0050770 regulation of axonogenesis ( 3.16752794728306e-08 ); GO:0045893 positive regulation of transcription, DNA-dependent ( 6.88604953983364e-06 ); GO:0007409 axonogenesis ( 0.000909735730545878 ); GO:0030030 cell projection organization ( 0.00124372125917679 ); GO:0010721 negative regulation of cell development ( 0.00266594127037729 ); GO:0051254 positive regulation of RNA metabolic process ( 0.0026938050909277 ); GO:0030955 potassium ion binding ( 0.00290997032417904 ); GO:0007420 brain development ( 0.00296938699814651 ); GO:0022604 regulation of cell morphogenesis ( 0.00315644488685318 ); GO:0031328 positive regulation of cellular biosynthetic process ( 0.00410354645919316 ); GO:0045595 regulation of cell differentiation ( 0.00632104655082788 ); GO:0000904 cell morphogenesis involved in differentiation ( 0.0084002663665815 ); GO:0030001 metal ion transport ( 4.14938538693213e-14 ); GO:0048709 oligodendrocyte differentiation ( 2.69149844232712e-11 ); GO:0004090 carbonyl reductase (NADPH) activity ( 5.13931410843501e-10 ); GO:0016782 transferase activity, transferring sulfur-containing groups ( 3.16752794728306e-08 ); GO:0005249 voltage-gated potassium channel activity ( 6.88604953983364e-06 ); GO:0010604 positive regulation of macromolecule metabolic process ( 0.000909735730545878 ); GO:0046873 metal ion transmembrane transporter activity ( 0.00124372125917679 ); GO:0032799 low-density lipoprotein receptor metabolic process ( 0.00266594127037729 ); GO:0005031 tumor necrosis factor receptor activity ( 0.0026938050909277 ); GO:0044459 plasma membrane part ( 0.00290997032417904 ); GO:0010557 positive regulation of macromolecule biosynthetic process ( 0.00296938699814651 ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( 0.00315644488685318 ); GO:0007267 cell-cell signaling ( 0.00410354645919316 ); GO:0048522 positive regulation of cellular process ( 0.00632104655082788 ); GO:0045095 keratin filament ( 0.0084002663665815 ); GO:0009891 positive regulation of biosynthetic process ( 4.14938538693213e-14 ); GO:0051128 regulation of cellular component organization ( 2.69149844232712e-11 ); GO:0048878 chemical homeostasis ( 5.13931410843501e-10 ); GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway ( 3.16752794728306e-08 ); GO:0021536 diencephalon development ( 6.88604953983364e-06 ); GO:0005184 neuropeptide hormone activity ( 0.000909735730545878 ); GO:0065008 regulation of biological quality ( 0.00124372125917679 ); GO:0008324 cation transmembrane transporter activity ( 0.00266594127037729 ); GO:0031325 positive regulation of cellular metabolic process ( 0.0026938050909277 ); GO:0031424 keratinization ( 0.00290997032417904 ); GO:0006936 muscle contraction ( 0.00296938699814651 ); GO:0009893 positive regulation of metabolic process ( 0.00315644488685318 ); GO:0048741 skeletal muscle fiber development ( 0.00410354645919316 ); GO:0007389 pattern specification process ( 0.00632104655082788 ); GO:0006814 sodium ion transport ( 0.0084002663665815 ); GO:0031226 intrinsic to plasma membrane ( 4.14938538693213e-14 ); GO:0035050 embryonic heart tube development ( 2.69149844232712e-11 ); GO:0043120 tumor necrosis factor binding ( 5.13931410843501e-10 ); GO:0003018 vascular process in circulatory system ( 3.16752794728306e-08 ); GO:0030528 transcription regulator activity ( 6.88604953983364e-06 ); GO:0010001 glial cell differentiation ( 0.000909735730545878 ); GO:0008307 structural constituent of muscle ( 0.00124372125917679 ); GO:0034703 cation channel complex ( 0.00266594127037729 ); GO:0031402 sodium ion binding ( 0.0026938050909277 ); GO:0048747 muscle fiber development ( 0.00290997032417904 ); GO:0005887 integral to plasma membrane ( 0.00296938699814651 ); GO:0043292 contractile fiber ( 0.00315644488685318 ); GO:0051239 regulation of multicellular organismal process ( 0.00410354645919316 ); GO:0048729 tissue morphogenesis ( 0.00632104655082788 ); GO:0048535 lymph node development ( 0.0084002663665815 ); GO:0017049 GTP-Rho binding ( 4.14938538693213e-14 ); GO:0005158 insulin receptor binding ( 2.69149844232712e-11 ); GO:0005604 basement membrane ( 5.13931410843501e-10 ); GO:0045165 cell fate commitment ( 3.16752794728306e-08 ); GO:0048515 spermatid differentiation ( 6.88604953983364e-06 ); GO:0050769 positive regulation of neurogenesis ( 0.000909735730545878 ); GO:0022603 regulation of anatomical structure morphogenesis ( 0.00124372125917679 ); GO:0031404 chloride ion binding ( 0.00266594127037729 ); GO:0043168 anion binding ( 0.0026938050909277 ); GO:0030900 forebrain development ( 0.00290997032417904 ); GO:0005254 chloride channel activity ( 0.00296938699814651 ); GO:0009888 tissue development ( 0.00315644488685318 ); GO:0007166 cell surface receptor linked signal transduction ( 0.00410354645919316 ); GO:0016020 membrane ( 0.00632104655082788 ); GO:0014902 myotube differentiation ( 0.0084002663665815 ); GO:0030901 midbrain development ( 4.14938538693213e-14 ); GO:0046717 acid secretion ( 2.69149844232712e-11 ); GO:0005035 death receptor activity ( 5.13931410843501e-10 ); GO:0004175 endopeptidase activity ( 3.16752794728306e-08 ); GO:0010552 positive regulation of specific transcription from RNA polymerase II promoter ( 6.88604953983364e-06 ); GO:0032102 negative regulation of response to external stimulus ( 0.000909735730545878 ); GO:0003012 muscle system process ( 0.00124372125917679 ); GO:0030016 myofibril ( 0.00266594127037729 ); GO:0021869 forebrain ventricular zone progenitor cell division ( 0.0026938050909277 ); GO:0030853 negative regulation of granulocyte differentiation ( 0.00290997032417904 ); GO:0048755 branching morphogenesis of a nerve ( 0.00296938699814651 ); GO:0055011 atrial cardiac muscle cell differentiation ( 0.00315644488685318 ); GO:0055014 atrial cardiac muscle cell development ( 0.00410354645919316 ); GO:0055098 response to low density lipoprotein stimulus ( 0.00632104655082788 ); GO:0060159 regulation of dopamine receptor signaling pathway ( 0.0084002663665815 ); GO:0005185 neurohypophyseal hormone activity ( 4.14938538693213e-14 ); GO:0034702 ion channel complex ( 2.69149844232712e-11 ); GO:0009790 embryonic development ( 5.13931410843501e-10 ); GO:0050794 regulation of cellular process ( 3.16752794728306e-08 ); GO:0044449 contractile fiber part ( 6.88604953983364e-06 ); GO:0048730 epidermis morphogenesis ( 0.000909735730545878 ); GO:0001763 morphogenesis of a branching structure ( 0.00124372125917679 ); GO:0004890 GABA-A receptor activity ( 0.00266594127037729 ); GO:0030017 sarcomere ( 0.0026938050909277 ); GO:0016049 cell growth ( 0.00290997032417904 ); GO:0048518 positive regulation of biological process ( 0.00296938699814651 ); GO:0014013 regulation of gliogenesis ( 0.00315644488685318 ); GO:0045685 regulation of glial cell differentiation ( 0.00410354645919316 ); GO:0008509 anion transmembrane transporter activity ( 0.00632104655082788 ); GO:0008146 sulfotransferase activity ( 0.0084002663665815 ); GO:0021854 hypothalamus development ( 4.14938538693213e-14 ); GO:0021895 cerebral cortex neuron differentiation ( 2.69149844232712e-11 ); GO:0030212 hyaluronan metabolic process ( 5.13931410843501e-10 ); GO:0030851 granulocyte differentiation ( 3.16752794728306e-08 ); GO:0043586 tongue development ( 6.88604953983364e-06 ); GO:0005587 collagen type IV ( 0.000909735730545878 ); GO:0005593 FACIT collagen ( 0.00124372125917679 ); GO:0008493 tetracycline transporter activity ( 0.00266594127037729 ); GO:0031490 chromatin DNA binding ( 0.0026938050909277 ); GO:0042895 antibiotic transporter activity ( 0.00290997032417904 ); GO:0043009 chordate embryonic development ( 0.00296938699814651 ); GO:0010720 positive regulation of cell development ( 0.00315644488685318 ); GO:0005272 sodium channel activity ( 0.00410354645919316 ); GO:0045665 negative regulation of neuron differentiation ( 0.00632104655082788 ); GO:0005253 anion channel activity ( 0.0084002663665815 ); GO:0032583 regulation of gene-specific transcription ( 4.14938538693213e-14 ); GO:0035150 regulation of tube size ( 2.69149844232712e-11 ); GO:0050880 regulation of blood vessel size ( 5.13931410843501e-10 ); GO:0008076 voltage-gated potassium channel complex ( 3.16752794728306e-08 ); GO:0034705 potassium channel complex ( 6.88604953983364e-06 ); GO:0050789 regulation of biological process ( 0.000909735730545878 ); GO:0005509 calcium ion binding ( 0.00124372125917679 ); GO:0003013 circulatory system process ( 0.00266594127037729 ); GO:0008015 blood circulation ( 0.0026938050909277 ); GO:0009792 embryonic development ending in birth or egg hatching ( 0.00290997032417904 ); ----------------GO-------------- GO:0005576 extracellular region ( 1.78537221988405e-12 ); GO:0048856 anatomical structure development ( 5.76204424282835e-11 ); GO:0048731 system development ( 1.19265337308525e-10 ); GO:0007275 multicellular organismal development ( 6.19802394173693e-10 ); GO:0048869 cellular developmental process ( 1.27921485287356e-09 ); GO:0005578 proteinaceous extracellular matrix ( 2.90942966329853e-09 ); GO:0048468 cell development ( 4.62249490128854e-09 ); GO:0030154 cell differentiation ( 7.1954906545096e-09 ); GO:0032501 multicellular organismal process ( 7.51869697546493e-09 ); GO:0048513 organ development ( 9.20456084943016e-09 ); GO:0031012 extracellular matrix ( 1.56347158450267e-08 ); GO:0005520 insulin-like growth factor binding ( 4.70881405018117e-08 ); GO:0007399 nervous system development ( 7.87453886618328e-08 ); GO:0050767 regulation of neurogenesis ( 1.19718282770222e-07 ); GO:0009653 anatomical structure morphogenesis ( 1.78952959578064e-07 ); GO:0060284 regulation of cell development ( 2.81458233810246e-07 ); GO:0051960 regulation of nervous system development ( 4.16092874084702e-07 ); GO:0045664 regulation of neuron differentiation ( 4.9512587471886e-07 ); GO:0044421 extracellular region part ( 7.63334880062954e-07 ); GO:0022008 neurogenesis ( 1.43542038183346e-06 ); GO:0043565 sequence-specific DNA binding ( 1.69769069343875e-06 ); GO:0048699 generation of neurons ( 1.94806773039558e-06 ); GO:0015267 channel activity ( 2.32671115818091e-06 ); GO:0022803 passive transmembrane transporter activity ( 2.32671115818091e-06 ); GO:0030182 neuron differentiation ( 4.56148481260597e-06 ); GO:0045666 positive regulation of neuron differentiation ( 4.78379012021819e-06 ); GO:0022838 substrate specific channel activity ( 5.11148865226377e-06 ); GO:0005581 collagen ( 6.53700673351499e-06 ); GO:0032502 developmental process ( 6.6734236400842e-06 ); GO:0005216 ion channel activity ( 1.11154968995865e-05 ); GO:0005244 voltage-gated ion channel activity ( 1.11307593892093e-05 ); GO:0022832 voltage-gated channel activity ( 1.11307593892093e-05 ); GO:0031224 intrinsic to membrane ( 2.58474111669576e-05 ); GO:0022836 gated channel activity ( 3.25715011520945e-05 ); GO:0007155 cell adhesion ( 7.60517030366773e-05 ); GO:0022610 biological adhesion ( 7.60517030366773e-05 ); GO:0044420 extracellular matrix part ( 9.85171926904744e-05 ); GO:0003700 transcription factor activity ( 9.91429809059231e-05 ); GO:0022857 transmembrane transporter activity ( 0.00010351732977197 ); GO:0016021 integral to membrane ( 0.000109819990056022 ); GO:0031420 alkali metal ion binding ( 0.000117716054568172 ); GO:0007417 central nervous system development ( 0.000133478373750194 ); GO:0007398 ectoderm development ( 0.000137303741666426 ); GO:0022891 substrate-specific transmembrane transporter activity ( 0.000160792875585497 ); GO:0044425 membrane part ( 0.000187103355578842 ); GO:0004252 serine-type endopeptidase activity ( 0.000209886401569737 ); GO:0015075 ion transmembrane transporter activity ( 0.000226602396703374 ); GO:0031344 regulation of cell projection organization ( 0.000250340725782696 ); GO:0030934 anchoring collagen ( 0.000260628255086119 ); GO:0006813 potassium ion transport ( 0.00026900202661731 ); GO:0005267 potassium channel activity ( 0.000278136580248028 ); GO:0009887 organ morphogenesis ( 0.00029868706014163 ); GO:0022892 substrate-specific transporter activity ( 0.00032733356258142 ); GO:0000902 cell morphogenesis ( 0.000363518545217938 ); GO:0032989 cellular structure morphogenesis ( 0.000363518545217938 ); GO:0048663 neuron fate commitment ( 0.000395635455325092 ); GO:0031346 positive regulation of cell projection organization ( 0.000400182666253782 ); GO:0031175 neurite development ( 0.000405160969066072 ); GO:0032922 circadian regulation of gene expression ( 0.000455921461593215 ); GO:0019838 growth factor binding ( 0.000456388016202699 ); GO:0008544 epidermis development ( 0.000484842572639588 ); GO:0048812 neurite morphogenesis ( 0.000484842572639588 ); GO:0005215 transporter activity ( 0.000495106556942058 ); GO:0015672 monovalent inorganic cation transport ( 0.00050961211446596 ); GO:0005261 cation channel activity ( 0.000511323875769407 ); GO:0001558 regulation of cell growth ( 0.000551880641343305 ); GO:0050772 positive regulation of axonogenesis ( 0.000563013655438204 ); GO:0022843 voltage-gated cation channel activity ( 0.000571015569083415 ); GO:0048667 cell morphogenesis involved in neuron differentiation ( 0.000590123081176727 ); GO:0007154 cell communication ( 0.000591242358440063 ); GO:0006811 ion transport ( 0.000634889290091123 ); GO:0010628 positive regulation of gene expression ( 0.000635011021511737 ); GO:0010769 regulation of cell morphogenesis involved in differentiation ( 0.000657865491263916 ); GO:0040008 regulation of growth ( 0.000668196400332798 ); GO:0045941 positive regulation of transcription ( 0.000679912486283734 ); GO:0005201 extracellular matrix structural constituent ( 0.000748371034718466 ); GO:0032990 cell part morphogenesis ( 0.000785320077800384 ); GO:0048858 cell projection morphogenesis ( 0.000785320077800384 ); GO:0010551 regulation of specific transcription from RNA polymerase II promoter ( 0.000834216531726923 ); GO:0032569 specific transcription from RNA polymerase II promoter ( 0.000834216531726923 ); GO:0016055 Wnt receptor signaling pathway ( 0.000844007291214631 ); GO:0045596 negative regulation of cell differentiation ( 0.000844007291214631 ); GO:0008236 serine-type peptidase activity ( 0.000853634813997588 ); GO:0042063 gliogenesis ( 0.000861785154503021 ); GO:0005886 plasma membrane ( 0.000910368472543958 ); GO:0017171 serine hydrolase activity ( 0.000933093696634976 ); GO:0050768 negative regulation of neurogenesis ( 0.000962870706229289 ); GO:0050793 regulation of developmental process ( 0.000981799443696996 ); GO:0048666 neuron development ( 0.000982810174071848 ); GO:0014014 negative regulation of gliogenesis ( 0.00101465391417192 ); GO:0045686 negative regulation of glial cell differentiation ( 0.00101465391417192 ); GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00102364234399278 ); GO:0035270 endocrine system development ( 0.00103502447281145 ); GO:0050770 regulation of axonogenesis ( 0.00120388379041864 ); GO:0045893 positive regulation of transcription, DNA-dependent ( 0.00122272156902941 ); GO:0007409 axonogenesis ( 0.00126234817561597 ); GO:0030030 cell projection organization ( 0.00129125043867114 ); GO:0010721 negative regulation of cell development ( 0.00129292499232006 ); GO:0051254 positive regulation of RNA metabolic process ( 0.00137571676783235 ); GO:0030955 potassium ion binding ( 0.00137884360670965 ); GO:0007420 brain development ( 0.00150910050317553 ); GO:0022604 regulation of cell morphogenesis ( 0.00154374017716309 ); GO:0031328 positive regulation of cellular biosynthetic process ( 0.00161830409801819 ); GO:0045595 regulation of cell differentiation ( 0.00167926789590682 ); GO:0000904 cell morphogenesis involved in differentiation ( 0.00169103245820743 ); GO:0030001 metal ion transport ( 0.00170805409194508 ); GO:0048709 oligodendrocyte differentiation ( 0.00170817630985508 ); GO:0004090 carbonyl reductase (NADPH) activity ( 0.00171854196782444 ); GO:0016782 transferase activity, transferring sulfur-containing groups ( 0.00173438763635241 ); GO:0005249 voltage-gated potassium channel activity ( 0.00186733241655611 ); GO:0010604 positive regulation of macromolecule metabolic process ( 0.00187639063774351 ); GO:0046873 metal ion transmembrane transporter activity ( 0.00190455073673103 ); GO:0032799 low-density lipoprotein receptor metabolic process ( 0.00190560407347557 ); GO:0005031 tumor necrosis factor receptor activity ( 0.00190560407347557 ); GO:0044459 plasma membrane part ( 0.00193146953258704 ); GO:0010557 positive regulation of macromolecule biosynthetic process ( 0.00197326233888784 ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( 0.00200226746069712 ); GO:0007267 cell-cell signaling ( 0.00200644692455532 ); GO:0048522 positive regulation of cellular process ( 0.0020136488815206 ); GO:0045095 keratin filament ( 0.00205620230436247 ); GO:0009891 positive regulation of biosynthetic process ( 0.00214361884143031 ); GO:0051128 regulation of cellular component organization ( 0.002208311190907 ); GO:0048878 chemical homeostasis ( 0.0023313327076522 ); GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway ( 0.00233538293502404 ); GO:0021536 diencephalon development ( 0.00233538293502404 ); GO:0005184 neuropeptide hormone activity ( 0.00233538293502404 ); GO:0065008 regulation of biological quality ( 0.00242447817047431 ); GO:0008324 cation transmembrane transporter activity ( 0.00254958426515995 ); GO:0031325 positive regulation of cellular metabolic process ( 0.00263376961759853 ); GO:0031424 keratinization ( 0.00286181586199106 ); GO:0006936 muscle contraction ( 0.00293883979707899 ); GO:0009893 positive regulation of metabolic process ( 0.0030032952073623 ); GO:0048741 skeletal muscle fiber development ( 0.00312061187712514 ); GO:0007389 pattern specification process ( 0.0031519782672653 ); GO:0006814 sodium ion transport ( 0.00320721089166079 ); GO:0031226 intrinsic to plasma membrane ( 0.00321809634216457 ); GO:0035050 embryonic heart tube development ( 0.00322158472818713 ); GO:0043120 tumor necrosis factor binding ( 0.00322158472818713 ); GO:0003018 vascular process in circulatory system ( 0.00322162391271987 ); GO:0030528 transcription regulator activity ( 0.00333754542805122 ); GO:0010001 glial cell differentiation ( 0.00342054813394637 ); GO:0008307 structural constituent of muscle ( 0.00342054813394637 ); GO:0034703 cation channel complex ( 0.00361415767699268 ); GO:0031402 sodium ion binding ( 0.00361415767699268 ); GO:0048747 muscle fiber development ( 0.00365537787823121 ); GO:0005887 integral to plasma membrane ( 0.00370547792206945 ); GO:0043292 contractile fiber ( 0.00375750899186695 ); GO:0051239 regulation of multicellular organismal process ( 0.00395313678404052 ); GO:0048729 tissue morphogenesis ( 0.00399248452961569 ); GO:0048535 lymph node development ( 0.00404965087168138 ); GO:0017049 GTP-Rho binding ( 0.00404965087168138 ); GO:0005158 insulin receptor binding ( 0.00408857484963917 ); GO:0005604 basement membrane ( 0.00427779550874713 ); GO:0045165 cell fate commitment ( 0.00439347967771699 ); GO:0048515 spermatid differentiation ( 0.00444749717310088 ); GO:0050769 positive regulation of neurogenesis ( 0.00444749717310088 ); GO:0022603 regulation of anatomical structure morphogenesis ( 0.00446295985523933 ); GO:0031404 chloride ion binding ( 0.00449282257428129 ); GO:0043168 anion binding ( 0.00449282257428129 ); GO:0030900 forebrain development ( 0.00469918762876364 ); GO:0005254 chloride channel activity ( 0.00473499648710814 ); GO:0009888 tissue development ( 0.00474424643608004 ); GO:0007166 cell surface receptor linked signal transduction ( 0.00496497597276478 ); GO:0016020 membrane ( 0.00503574205176328 ); GO:0014902 myotube differentiation ( 0.00504386451831126 ); GO:0030901 midbrain development ( 0.00504386451831126 ); GO:0046717 acid secretion ( 0.00504386451831126 ); GO:0005035 death receptor activity ( 0.00504386451831126 ); GO:0004175 endopeptidase activity ( 0.0052363631140659 ); GO:0010552 positive regulation of specific transcription from RNA polymerase II promoter ( 0.00526071390341787 ); GO:0032102 negative regulation of response to external stimulus ( 0.00526071390341787 ); GO:0003012 muscle system process ( 0.00540092727401403 ); GO:0030016 myofibril ( 0.0056543216162588 ); GO:0021869 forebrain ventricular zone progenitor cell division ( 0.0059272769885952 ); GO:0030853 negative regulation of granulocyte differentiation ( 0.0059272769885952 ); GO:0048755 branching morphogenesis of a nerve ( 0.0059272769885952 ); GO:0055011 atrial cardiac muscle cell differentiation ( 0.0059272769885952 ); GO:0055014 atrial cardiac muscle cell development ( 0.0059272769885952 ); GO:0055098 response to low density lipoprotein stimulus ( 0.0059272769885952 ); GO:0060159 regulation of dopamine receptor signaling pathway ( 0.0059272769885952 ); GO:0005185 neurohypophyseal hormone activity ( 0.0059272769885952 ); GO:0034702 ion channel complex ( 0.00597387211846744 ); GO:0009790 embryonic development ( 0.00605008273060611 ); GO:0050794 regulation of cellular process ( 0.00611885470858374 ); GO:0044449 contractile fiber part ( 0.00631878254732222 ); GO:0048730 epidermis morphogenesis ( 0.00635901348092276 ); GO:0001763 morphogenesis of a branching structure ( 0.00655730012952787 ); GO:0004890 GABA-A receptor activity ( 0.00666110998968769 ); GO:0030017 sarcomere ( 0.00679180611676441 ); GO:0016049 cell growth ( 0.00692137247039925 ); GO:0048518 positive regulation of biological process ( 0.00720845721556521 ); GO:0014013 regulation of gliogenesis ( 0.00744706219239955 ); GO:0045685 regulation of glial cell differentiation ( 0.00744706219239955 ); GO:0008509 anion transmembrane transporter activity ( 0.00759780614937834 ); GO:0008146 sulfotransferase activity ( 0.00760795424561911 ); GO:0021854 hypothalamus development ( 0.00763613756096718 ); GO:0021895 cerebral cortex neuron differentiation ( 0.00763613756096718 ); GO:0030212 hyaluronan metabolic process ( 0.00763613756096718 ); GO:0030851 granulocyte differentiation ( 0.00763613756096718 ); GO:0043586 tongue development ( 0.00763613756096718 ); GO:0005587 collagen type IV ( 0.00763613756096718 ); GO:0005593 FACIT collagen ( 0.00763613756096718 ); GO:0008493 tetracycline transporter activity ( 0.00763613756096718 ); GO:0031490 chromatin DNA binding ( 0.00763613756096718 ); GO:0042895 antibiotic transporter activity ( 0.00763613756096718 ); GO:0043009 chordate embryonic development ( 0.00771612590838319 ); GO:0010720 positive regulation of cell development ( 0.00806738344075012 ); GO:0005272 sodium channel activity ( 0.00806738344075012 ); GO:0045665 negative regulation of neuron differentiation ( 0.00831308089375933 ); GO:0005253 anion channel activity ( 0.00851456389905284 ); GO:0032583 regulation of gene-specific transcription ( 0.00855591072674372 ); GO:0035150 regulation of tube size ( 0.00855591072674372 ); GO:0050880 regulation of blood vessel size ( 0.00855591072674372 ); GO:0008076 voltage-gated potassium channel complex ( 0.00869075220835651 ); GO:0034705 potassium channel complex ( 0.00869075220835651 ); GO:0050789 regulation of biological process ( 0.0090974822941987 ); GO:0005509 calcium ion binding ( 0.00923951605979847 ); GO:0003013 circulatory system process ( 0.00936892010678337 ); GO:0008015 blood circulation ( 0.00936892010678337 ); GO:0009792 embryonic development ending in birth or egg hatching ( 0.00936892010678337 ); ----------------KEGG-------------- hsa01430 Cell junctions ( 4.32852873953926e-05 ); hsa05217 Basal cell carcinoma ( 0.00021651774375023 ); hsa04512 ECM-receptor interaction ( 0.000524732614107271 ); hsa04340 Hedgehog signaling pathway ( 0.010991212077954 ); hsa04310 Wnt signaling pathway ( 0.0120596934412359 ); hsa04510 Focal adhesion ( 0.0314540390050612 ); ----------------CARTA-------------- setpathway ( 0.0126022502960636 ); mitochondriapathway ( 0.0301608075164541 ); rbpathway ( 0.0320214341173738 ); raccycdpathway ( 0.0391644286738383 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.02921316153155 ); ----------------ARE-------------- ( ); ============================ group14 ========================= ----------------C2-------------- REACTOME_DIABETES_PATHWAYS ( 0.00143776794171619 ); REACTOME_GENE_EXPRESSION ( 0.00176079549795236 ); REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS ( 0.00234678137899265 ); BIOCARTA_CERAMIDE_PATHWAY ( 0.00301613367671284 ); REACTOME_PEPTIDE_CHAIN_ELONGATION ( 0.00538676781979498 ); REACTOME_VIRAL_MRNA_TRANSLATION ( 0.00538676781979498 ); KEGG_RIBOSOME ( 0.00624309638556485 ); KEGG_SPLICEOSOME ( 0.0067452037577902 ); REACTOME_INSULIN_SYNTHESIS_AND_SECRETION ( 0.00754698274664299 ); KEGG_CITRATE_CYCLE_TCA_CYCLE ( 0.00805907438714588 ); REACTOME_METABOLISM_OF_RNA ( 0.00823460759082313 ); REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS ( 0.00860469001187016 ); REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE ( 0.00904740753050574 ); KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM ( 0.00959255113200796 ); BIOCARTA_MPR_PATHWAY ( 0.00959255113200796 ); ----------------C3-------------- GGGCGGR_V$SP1_Q6 ( 2.17528730609444e-05 ); SCGGAAGY_V$ELK1_02 ( 5.17414231955387e-05 ); GCGNNANTTCC_UNKNOWN ( 0.000918539009505876 ); RCGCANGCGY_V$NRF1_Q6 ( 0.00209333821998746 ); MGGAAGTG_V$GABP_B ( 0.00369859951266003 ); RNGTGGGC_UNKNOWN ( 0.00802280606262878 ); ----------------C4-------------- MORF_RAN ( 1.15526056291284e-06 ); MORF_IKBKG ( 3.62797571586473e-06 ); GCM_ING1 ( 4.31782478867886e-06 ); MORF_DAP3 ( 4.60013546143378e-06 ); MORF_CSNK2B ( 1.05820181117605e-05 ); MORF_HDAC1 ( 1.12558883279115e-05 ); MORF_RPA2 ( 1.78155764160516e-05 ); MORF_DDB1 ( 4.30984345795184e-05 ); module_388 ( 6.4852433299408e-05 ); MORF_XPC ( 9.04363328925088e-05 ); MORF_SOD1 ( 0.000135217813026612 ); MORF_G22P1 ( 0.000173658597859907 ); MORF_PRKAG1 ( 0.000390206500809802 ); MORF_AATF ( 0.000675030735391148 ); MORF_PHB ( 0.000735506712704235 ); MORF_NME2 ( 0.000757269538671419 ); GCM_TINF2 ( 0.000942528816977121 ); GCM_NF2 ( 0.00114137227018074 ); MORF_RAD23A ( 0.00121597058763544 ); GCM_CSNK2B ( 0.00131650387167375 ); MORF_AP2M1 ( 0.00137911735352599 ); MORF_PML ( 0.00154441160830326 ); MORF_CSNK1D ( 0.00176842110016661 ); MORF_PRKAR1A ( 0.00201524086364828 ); MORF_UBE2I ( 0.00213625314503804 ); MORF_TPT1 ( 0.00225685558343185 ); GCM_MYST2 ( 0.00248655968387323 ); GCM_NUMA1 ( 0.0025606468543696 ); MORF_ANP32B ( 0.00268945641136191 ); MORF_ERH ( 0.00274877700081026 ); GCM_NPM1 ( 0.00347174566230439 ); MORF_EIF3S6 ( 0.00363183091866847 ); MORF_FANCG ( 0.00367961150787562 ); module_32 ( 0.00391234181785084 ); MORF_CTBP1 ( 0.00411077400883715 ); MORF_NPM1 ( 0.0045791760874998 ); MORF_RAC1 ( 0.00483188583378213 ); MORF_RAD23B ( 0.00526504523786006 ); MORF_AP3D1 ( 0.00532968438576126 ); module_265 ( 0.00545390706802015 ); module_256 ( 0.00547587634661699 ); GNF2_FBL ( 0.00600709288851094 ); MORF_FBL ( 0.00624623826288079 ); GCM_UBE2N ( 0.00649223859262049 ); GNF2_ST13 ( 0.00708681125754083 ); module_337 ( 0.00753337775335196 ); MORF_FEN1 ( 0.00799808198994536 ); MORF_RAD54L ( 0.00823460759082313 ); GCM_PRKCG ( 0.00848121366841034 ); MORF_MTA1 ( 0.00860469001187016 ); MORF_RFC1 ( 0.00937907703234281 ); MORF_RAB1A ( 0.00962031462351026 ); MORF_EIF3S2 ( 0.00997879069225186 ); ----------------C5-------------- CYTOPLASM ( 7.87913984758816e-06 ); CYTOPLASMIC_PART ( 8.90576428485604e-06 ); INTRACELLULAR_ORGANELLE_PART ( 0.000333978208790237 ); ORGANELLE_PART ( 0.000359214799875217 ); STRUCTURAL_MOLECULE_ACTIVITY ( 0.000435679304077822 ); ACTIN_BINDING ( 0.000539860983533807 ); STRUCTURAL_CONSTITUENT_OF_RIBOSOME ( 0.000709840812410817 ); MACROMOLECULAR_COMPLEX ( 0.00123401176103156 ); ACTIN_CYTOSKELETON ( 0.00161623921273538 ); NON_MEMBRANE_BOUND_ORGANELLE ( 0.00387246416501707 ); INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE ( 0.00387246416501707 ); OXIDOREDUCTASE_ACTIVITY__ACTING_ON_NADH_OR_NADPH ( 0.00388680321921796 ); NUCLEUS ( 0.0043429255819367 ); ACTIN_FILAMENT_BINDING ( 0.00437361221890606 ); MITOCHONDRION ( 0.00528202776854626 ); CYTOSKELETAL_PROTEIN_BINDING ( 0.00544795513399233 ); ORGANELLE_LUMEN ( 0.00619454733800611 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00619454733800611 ); NUCLEAR_PART ( 0.00673498847574399 ); RIBONUCLEOPROTEIN_COMPLEX ( 0.00782890003640445 ); HEMATOPOIETIN_INTERFERON_CLASS__D200_DOMAIN__CYTOKINE_RECEPTOR_ACTIVITY ( 0.00880618546700515 ); 3__5__EXONUCLEASE_ACTIVITY ( 0.00904740753050574 ); CYTOSKELETON ( 0.00925406035765979 ); ----------------GOSLIM-------------- GO:0043229 intracellular organelle ( 4.38042364481784e-10 ); GO:0043226 organelle ( 4.97583251369583e-09 ); GO:0044424 intracellular part ( 3.63639116911367e-07 ); GO:0005737 cytoplasm ( 1.38668224061507e-05 ); GO:0005622 intracellular ( 0.000407112679263163 ); GO:0044444 cytoplasmic part ( 0.000837598921763873 ); GO:0043231 intracellular membrane-bounded organelle ( 0.000864857419776728 ); GO:0043227 membrane-bounded organelle ( 0.00287340184408879 ); GO:0032991 macromolecular complex ( 0.00348733654901405 ); GO:0044446 intracellular organelle part ( 0.00396283972412636 ); GO:0044422 organelle part ( 0.00647263848529266 ); GO:0042809 vitamin D receptor binding ( 0.00915578133316703 ); GO:0005739 mitochondrion ( 0.00915743614971296 ); GO:0008152 metabolic process ( 4.38042364481784e-10 ); GO:0051015 actin filament binding ( 4.97583251369583e-09 ); GO:0045010 actin nucleation ( 3.63639116911367e-07 ); GO:0010861 thyroid hormone receptor activator activity ( 1.38668224061507e-05 ); GO:0030375 thyroid hormone receptor coactivator activity ( 0.000407112679263163 ); GO:0046966 thyroid hormone receptor binding ( 0.000837598921763873 ); GO:0051186 cofactor metabolic process ( 0.000864857419776728 ); GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity ( 0.00287340184408879 ); GO:0030546 receptor activator activity ( 0.00348733654901405 ); GO:0015629 actin cytoskeleton ( 0.00396283972412636 ); GO:0005515 protein binding ( 0.00647263848529266 ); GO:0065003 macromolecular complex assembly ( 0.00915578133316703 ); GO:0000049 tRNA binding ( 0.00915743614971296 ); GO:0043933 macromolecular complex subunit organization ( 4.38042364481784e-10 ); GO:0030529 ribonucleoprotein complex ( 4.97583251369583e-09 ); GO:0016071 mRNA metabolic process ( 3.63639116911367e-07 ); GO:0006732 coenzyme metabolic process ( 1.38668224061507e-05 ); GO:0007015 actin filament organization ( 0.000407112679263163 ); GO:0006414 translational elongation ( 0.000837598921763873 ); GO:0022607 cellular component assembly ( 0.000864857419776728 ); GO:0016651 oxidoreductase activity, acting on NADH or NADPH ( 0.00287340184408879 ); GO:0043234 protein complex ( 0.00348733654901405 ); GO:0042301 phosphate binding ( 0.00396283972412636 ); GO:0044237 cellular metabolic process ( 0.00647263848529266 ); GO:0006099 tricarboxylic acid cycle ( 0.00915578133316703 ); GO:0046356 acetyl-CoA catabolic process ( 0.00915743614971296 ); GO:0000375 RNA splicing, via transesterification reactions ( 4.38042364481784e-10 ); GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile ( 4.97583251369583e-09 ); GO:0000398 nuclear mRNA splicing, via spliceosome ( 3.63639116911367e-07 ); GO:0004128 cytochrome-b5 reductase activity ( 1.38668224061507e-05 ); GO:0008565 protein transporter activity ( 0.000407112679263163 ); GO:0006084 acetyl-CoA metabolic process ( 0.000837598921763873 ); GO:0030545 receptor regulator activity ( 0.000864857419776728 ); GO:0016788 hydrolase activity, acting on ester bonds ( 0.00287340184408879 ); GO:0016615 malate dehydrogenase activity ( 0.00348733654901405 ); GO:0016653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ( 0.00396283972412636 ); GO:0009109 coenzyme catabolic process ( 0.00647263848529266 ); GO:0004091 carboxylesterase activity ( 0.00915578133316703 ); GO:0031290 retinal ganglion cell axon guidance ( 0.00915743614971296 ); GO:0042177 negative regulation of protein catabolic process ( 4.38042364481784e-10 ); GO:0044238 primary metabolic process ( 4.97583251369583e-09 ); GO:0006397 mRNA processing ( 3.63639116911367e-07 ); GO:0006396 RNA processing ( 1.38668224061507e-05 ); GO:0004886 retinoid-X receptor activity ( 0.000407112679263163 ); GO:0030036 actin cytoskeleton organization ( 0.000837598921763873 ); GO:0000323 lytic vacuole ( 0.000864857419776728 ); GO:0005764 lysosome ( 0.00287340184408879 ); GO:0051187 cofactor catabolic process ( 0.00348733654901405 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.00396283972412636 ); GO:0005681 spliceosome ( 0.00647263848529266 ); GO:0031090 organelle membrane ( 0.00915578133316703 ); GO:0034621 cellular macromolecular complex subunit organization ( 0.00915743614971296 ); GO:0003713 transcription coactivator activity ( 4.38042364481784e-10 ); ----------------GO-------------- GO:0043229 intracellular organelle ( 7.67623870013189e-08 ); GO:0043226 organelle ( 7.89089080423888e-08 ); GO:0044424 intracellular part ( 1.48267497623988e-07 ); GO:0005737 cytoplasm ( 5.17500807868112e-07 ); GO:0005622 intracellular ( 7.28423919790888e-07 ); GO:0044444 cytoplasmic part ( 1.13318117002752e-06 ); GO:0043231 intracellular membrane-bounded organelle ( 2.36278866918346e-05 ); GO:0043227 membrane-bounded organelle ( 2.41635741141516e-05 ); GO:0032991 macromolecular complex ( 4.40316687816031e-05 ); GO:0044446 intracellular organelle part ( 6.07328126707986e-05 ); GO:0044422 organelle part ( 7.06293100532313e-05 ); GO:0042809 vitamin D receptor binding ( 8.25076508557101e-05 ); GO:0005739 mitochondrion ( 0.00011376726610557 ); GO:0008152 metabolic process ( 0.000146391975367722 ); GO:0051015 actin filament binding ( 0.000163428550968742 ); GO:0045010 actin nucleation ( 0.000178134802815817 ); GO:0010861 thyroid hormone receptor activator activity ( 0.000264628129229448 ); GO:0030375 thyroid hormone receptor coactivator activity ( 0.000264628129229448 ); GO:0046966 thyroid hormone receptor binding ( 0.000316870554838529 ); GO:0051186 cofactor metabolic process ( 0.000325429065427651 ); GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity ( 0.000430475572046828 ); GO:0030546 receptor activator activity ( 0.000612211763711961 ); GO:0015629 actin cytoskeleton ( 0.000660248759417621 ); GO:0005515 protein binding ( 0.000747722193476917 ); GO:0065003 macromolecular complex assembly ( 0.00114205562912196 ); GO:0000049 tRNA binding ( 0.00116366957892382 ); GO:0043933 macromolecular complex subunit organization ( 0.00118509967915016 ); GO:0030529 ribonucleoprotein complex ( 0.00128636548088668 ); GO:0016071 mRNA metabolic process ( 0.00162167588443859 ); GO:0006732 coenzyme metabolic process ( 0.00184741508298364 ); GO:0007015 actin filament organization ( 0.00203736379135442 ); GO:0006414 translational elongation ( 0.00214499170406702 ); GO:0022607 cellular component assembly ( 0.00236931280851757 ); GO:0016651 oxidoreductase activity, acting on NADH or NADPH ( 0.00245509835072763 ); GO:0043234 protein complex ( 0.00264280118342245 ); GO:0042301 phosphate binding ( 0.00301613367671284 ); GO:0044237 cellular metabolic process ( 0.0034327739631471 ); GO:0006099 tricarboxylic acid cycle ( 0.00343457563513303 ); GO:0046356 acetyl-CoA catabolic process ( 0.00343457563513303 ); GO:0000375 RNA splicing, via transesterification reactions ( 0.00354382892508647 ); GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile ( 0.00354382892508647 ); GO:0000398 nuclear mRNA splicing, via spliceosome ( 0.00354382892508647 ); GO:0004128 cytochrome-b5 reductase activity ( 0.00357858044260412 ); GO:0008565 protein transporter activity ( 0.00371680079368733 ); GO:0006084 acetyl-CoA metabolic process ( 0.00437361221890606 ); GO:0030545 receptor regulator activity ( 0.00437361221890606 ); GO:0016788 hydrolase activity, acting on ester bonds ( 0.0044731887675826 ); GO:0016615 malate dehydrogenase activity ( 0.00472945036965689 ); GO:0016653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ( 0.00472945036965689 ); GO:0009109 coenzyme catabolic process ( 0.00489574801291201 ); GO:0004091 carboxylesterase activity ( 0.00566235258171992 ); GO:0031290 retinal ganglion cell axon guidance ( 0.00602726818430268 ); GO:0042177 negative regulation of protein catabolic process ( 0.00602726818430268 ); GO:0044238 primary metabolic process ( 0.00609355647029194 ); GO:0006397 mRNA processing ( 0.00627719317225484 ); GO:0006396 RNA processing ( 0.00669894856542372 ); GO:0004886 retinoid-X receptor activity ( 0.00746792819807098 ); GO:0030036 actin cytoskeleton organization ( 0.00787541134386425 ); GO:0000323 lytic vacuole ( 0.00803266960925575 ); GO:0005764 lysosome ( 0.00803266960925575 ); GO:0051187 cofactor catabolic process ( 0.00805907438714588 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.00831099385803725 ); GO:0005681 spliceosome ( 0.00841537051208045 ); GO:0031090 organelle membrane ( 0.00906479914016846 ); GO:0034621 cellular macromolecular complex subunit organization ( 0.00931206840047211 ); GO:0003713 transcription coactivator activity ( 0.009905702902834 ); ----------------KEGG-------------- hsa00720 Reductive carboxylate cycle (CO2 fixation) ( 0.000264628129229448 ); hsa00020 Citrate cycle (TCA cycle) ( 0.00805907438714588 ); hsa00860 Porphyrin and chlorophyll metabolism ( 0.00959255113200796 ); hsa03010 Ribosome ( 0.0158112540617913 ); hsa05210 Colorectal cancer ( 0.0262228691517443 ); hsa00480 Glutathione metabolism ( 0.0292133791443643 ); hsa05221 Acute myeloid leukemia ( 0.0389950910646999 ); ----------------CARTA-------------- pcafpathway ( 0.00746792819807098 ); il4pathway ( 0.0166758772519185 ); gabapathway ( 0.0188919069194892 ); ppargpathway ( 0.0395825730367075 ); ----------------RBP-------------- ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 7.65942066073317e-18 ); AGO2_PAR-CLIP_(Kishore_2011) ( 4.3037062098213e-17 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 6.95685653431989e-16 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 7.11587181329795e-14 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 8.95046578194936e-14 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 3.21007640088364e-05 ); TIA1_iCLIP_(Wang_2010) ( 0.000828430143530244 ); TIAL1_iCLIP_(Wang_2010) ( 0.00135839209447758 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.00673393191683997 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0274526531942918 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group16 ========================= ----------------C2-------------- REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS ( 0.00068243286758512 ); KEGG_ECM_RECEPTOR_INTERACTION ( 0.000829343346902527 ); KEGG_FOCAL_ADHESION ( 0.00135584365399445 ); REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY ( 0.00891699052975327 ); KEGG_CALCIUM_SIGNALING_PATHWAY ( 0.00952857854867493 ); ----------------C3-------------- V$CP2_01 ( 0.00121936350087622 ); V$FREAC4_01 ( 0.00350033266535026 ); V$ERR1_Q2 ( 0.00395484481352602 ); GGATCCG,MIR-127 ( 0.00466034518069848 ); GGGAGGRR_V$MAZ_Q6 ( 0.00580522120154216 ); V$AP4_Q6 ( 0.00703134742881372 ); V$ISRE_01 ( 0.00772239037547266 ); V$NFKB_Q6_01 ( 0.00772239037547266 ); ARGGGTTAA_UNKNOWN ( 0.00909693260850282 ); V$PEA3_Q6 ( 0.00952857854867493 ); ----------------C4-------------- module_2 ( 0.0014104162624921 ); module_274 ( 0.00447274979372024 ); ----------------C5-------------- EXTRACELLULAR_REGION ( 7.91194239203218e-08 ); EXTRACELLULAR_REGION_PART ( 4.57155891181835e-07 ); EXTRACELLULAR_SPACE ( 1.88730421829786e-05 ); RECEPTOR_BINDING ( 0.00127991982231193 ); PROTEINACEOUS_EXTRACELLULAR_MATRIX ( 0.00186184227135208 ); EXTRACELLULAR_MATRIX ( 0.0020654463856712 ); LIPID_TRANSPORTER_ACTIVITY ( 0.00534095533374148 ); EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT ( 0.00534095533374148 ); CELLULAR_DEFENSE_RESPONSE ( 0.00570051542330635 ); GROWTH_FACTOR_ACTIVITY ( 0.00570051542330635 ); FUCOSYLTRANSFERASE_ACTIVITY ( 0.00735979027389661 ); NEUROPEPTIDE_HORMONE_ACTIVITY ( 0.00891699052975327 ); ----------------GOSLIM-------------- GO:0005576 extracellular region ( 5.70614463694503e-07 ); GO:0044421 extracellular region part ( 1.09681987001946e-05 ); GO:0045202 synapse ( 0.000915490834175438 ); GO:0005578 proteinaceous extracellular matrix ( 0.0057600092932232 ); GO:0031012 extracellular matrix ( 5.70614463694503e-07 ); GO:0015872 dopamine transport ( 1.09681987001946e-05 ); GO:0004992 platelet activating factor receptor activity ( 0.000915490834175438 ); GO:0045095 keratin filament ( 0.0057600092932232 ); GO:0005882 intermediate filament ( 5.70614463694503e-07 ); GO:0006004 fucose metabolic process ( 1.09681987001946e-05 ); GO:0005201 extracellular matrix structural constituent ( 0.000915490834175438 ); GO:0045111 intermediate filament cytoskeleton ( 0.0057600092932232 ); GO:0051937 catecholamine transport ( 5.70614463694503e-07 ); GO:0042053 regulation of dopamine metabolic process ( 1.09681987001946e-05 ); GO:0042069 regulation of catecholamine metabolic process ( 0.000915490834175438 ); GO:0048385 regulation of retinoic acid receptor signaling pathway ( 0.0057600092932232 ); GO:0008035 high-density lipoprotein binding ( 5.70614463694503e-07 ); GO:0005615 extracellular space ( 1.09681987001946e-05 ); GO:0046903 secretion ( 0.000915490834175438 ); GO:0006816 calcium ion transport ( 0.0057600092932232 ); GO:0005102 receptor binding ( 5.70614463694503e-07 ); GO:0007631 feeding behavior ( 1.09681987001946e-05 ); GO:0021546 rhombomere development ( 0.000915490834175438 ); GO:0033238 regulation of cellular amine metabolic process ( 0.0057600092932232 ); GO:0060078 regulation of postsynaptic membrane potential ( 5.70614463694503e-07 ); GO:0005606 laminin-1 complex ( 1.09681987001946e-05 ); GO:0043256 laminin complex ( 0.000915490834175438 ); GO:0044456 synapse part ( 0.0057600092932232 ); GO:0005230 extracellular ligand-gated ion channel activity ( 5.70614463694503e-07 ); GO:0032940 secretion by cell ( 1.09681987001946e-05 ); GO:0005125 cytokine activity ( 0.000915490834175438 ); GO:0005231 excitatory extracellular ligand-gated ion channel activity ( 0.0057600092932232 ); GO:0051046 regulation of secretion ( 5.70614463694503e-07 ); GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ( 1.09681987001946e-05 ); GO:0030054 cell junction ( 0.000915490834175438 ); GO:0015844 monoamine transport ( 0.0057600092932232 ); GO:0006836 neurotransmitter transport ( 5.70614463694503e-07 ); GO:0008343 adult feeding behavior ( 1.09681987001946e-05 ); GO:0006584 catecholamine metabolic process ( 0.000915490834175438 ); GO:0045211 postsynaptic membrane ( 0.0057600092932232 ); GO:0018958 phenol metabolic process ( 5.70614463694503e-07 ); GO:0060341 regulation of cellular localization ( 1.09681987001946e-05 ); GO:0019317 fucose catabolic process ( 0.000915490834175438 ); GO:0042355 L-fucose catabolic process ( 0.0057600092932232 ); GO:0042423 catecholamine biosynthetic process ( 5.70614463694503e-07 ); GO:0006968 cellular defense response ( 1.09681987001946e-05 ); GO:0030168 platelet activation ( 0.000915490834175438 ); GO:0015674 di-, tri-valent inorganic cation transport ( 0.0057600092932232 ); GO:0001662 behavioral fear response ( 5.70614463694503e-07 ); GO:0001964 startle response ( 1.09681987001946e-05 ); GO:0002209 behavioral defense response ( 0.000915490834175438 ); GO:0004016 adenylate cyclase activity ( 0.0057600092932232 ); GO:0044420 extracellular matrix part ( 5.70614463694503e-07 ); GO:0001505 regulation of neurotransmitter levels ( 1.09681987001946e-05 ); GO:0042354 L-fucose metabolic process ( 0.000915490834175438 ); GO:0048384 retinoic acid receptor signaling pathway ( 0.0057600092932232 ); GO:0048483 autonomic nervous system development ( 5.70614463694503e-07 ); GO:0005583 fibrillar collagen ( 1.09681987001946e-05 ); GO:0032879 regulation of localization ( 0.000915490834175438 ); ----------------GO-------------- GO:0005576 extracellular region ( 3.12822559453018e-06 ); GO:0044421 extracellular region part ( 6.66948547653274e-06 ); GO:0045202 synapse ( 1.1561790160038e-05 ); GO:0005578 proteinaceous extracellular matrix ( 0.000142375989896592 ); GO:0031012 extracellular matrix ( 0.000225979914034205 ); GO:0015872 dopamine transport ( 0.000465251287750833 ); GO:0004992 platelet activating factor receptor activity ( 0.000521761141280054 ); GO:0045095 keratin filament ( 0.000556522229410717 ); GO:0005882 intermediate filament ( 0.00136287749451752 ); GO:0006004 fucose metabolic process ( 0.00136913681211692 ); GO:0005201 extracellular matrix structural constituent ( 0.00138423452199492 ); GO:0045111 intermediate filament cytoskeleton ( 0.00141803851282463 ); GO:0051937 catecholamine transport ( 0.00162693799356522 ); GO:0042053 regulation of dopamine metabolic process ( 0.00170884197070771 ); GO:0042069 regulation of catecholamine metabolic process ( 0.00170884197070771 ); GO:0048385 regulation of retinoic acid receptor signaling pathway ( 0.00170884197070771 ); GO:0008035 high-density lipoprotein binding ( 0.00170884197070771 ); GO:0005615 extracellular space ( 0.00172552270936678 ); GO:0046903 secretion ( 0.00193574608584434 ); GO:0006816 calcium ion transport ( 0.00219399267473149 ); GO:0005102 receptor binding ( 0.00244531948033036 ); GO:0007631 feeding behavior ( 0.00249182571008305 ); GO:0021546 rhombomere development ( 0.00254082684014569 ); GO:0033238 regulation of cellular amine metabolic process ( 0.00254082684014569 ); GO:0060078 regulation of postsynaptic membrane potential ( 0.00254082684014569 ); GO:0005606 laminin-1 complex ( 0.00254082684014569 ); GO:0043256 laminin complex ( 0.00254082684014569 ); GO:0044456 synapse part ( 0.00256778383169503 ); GO:0005230 extracellular ligand-gated ion channel activity ( 0.00268891303343675 ); GO:0032940 secretion by cell ( 0.00275174098068772 ); GO:0005125 cytokine activity ( 0.00325680179121536 ); GO:0005231 excitatory extracellular ligand-gated ion channel activity ( 0.00345562332663504 ); GO:0051046 regulation of secretion ( 0.00350033266535026 ); GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ( 0.00352605556621119 ); GO:0030054 cell junction ( 0.00364694946757588 ); GO:0015844 monoamine transport ( 0.00380546281342716 ); GO:0006836 neurotransmitter transport ( 0.00401920047100075 ); GO:0008343 adult feeding behavior ( 0.00466034518069848 ); GO:0006584 catecholamine metabolic process ( 0.00479400210817239 ); GO:0045211 postsynaptic membrane ( 0.00514051443008411 ); GO:0018958 phenol metabolic process ( 0.00534095533374148 ); GO:0060341 regulation of cellular localization ( 0.00535241330085774 ); GO:0019317 fucose catabolic process ( 0.00593959602189731 ); GO:0042355 L-fucose catabolic process ( 0.00593959602189731 ); GO:0042423 catecholamine biosynthetic process ( 0.00593959602189731 ); GO:0006968 cellular defense response ( 0.00608469144295132 ); GO:0030168 platelet activation ( 0.00654344665106475 ); GO:0015674 di-, tri-valent inorganic cation transport ( 0.00681153903699354 ); GO:0001662 behavioral fear response ( 0.00735979027389661 ); GO:0001964 startle response ( 0.00735979027389661 ); GO:0002209 behavioral defense response ( 0.00735979027389661 ); GO:0004016 adenylate cyclase activity ( 0.00735979027389661 ); GO:0044420 extracellular matrix part ( 0.00871510967742893 ); GO:0001505 regulation of neurotransmitter levels ( 0.00875385867869655 ); GO:0042354 L-fucose metabolic process ( 0.00891699052975327 ); GO:0048384 retinoic acid receptor signaling pathway ( 0.00891699052975327 ); GO:0048483 autonomic nervous system development ( 0.00891699052975327 ); GO:0005583 fibrillar collagen ( 0.00891699052975327 ); GO:0032879 regulation of localization ( 0.00930311459940166 ); ----------------KEGG-------------- hsa01430 Cell junctions ( 0.000495490309242555 ); hsa04512 ECM-receptor interaction ( 0.000829343346902527 ); hsa04510 Focal adhesion ( 0.00135584365399445 ); hsa04020 Calcium signaling pathway ( 0.0098098090779758 ); hsa05014 Amyotrophic lateral sclerosis (ALS) ( 0.0365648635762778 ); hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series ( 0.0462685049035197 ); ----------------CARTA-------------- eponfkbpathway ( 0.0263665385602233 ); ppargpathway ( 0.0392889272696947 ); il1rpathway ( 0.0495427088691021 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.00593453246719551 ); ----------------ARE-------------- ( ); ============================ group18 ========================= ----------------C2-------------- KEGG_FOCAL_ADHESION ( 0.000534788913552973 ); KEGG_RENAL_CELL_CARCINOMA ( 0.00154352243211518 ); REACTOME_OPIOID_SIGNALLING ( 0.00275812649814569 ); REACTOME_INTEGRATION_OF_ENERGY_METABOLISM ( 0.00425421046125625 ); KEGG_ALZHEIMERS_DISEASE ( 0.00498016827972087 ); REACTOME_AXON_GUIDANCE ( 0.00554077640621086 ); BIOCARTA_PTEN_PATHWAY ( 0.00708510593819833 ); BIOCARTA_TGFB_PATHWAY ( 0.00708510593819833 ); BIOCARTA_MAL_PATHWAY ( 0.00788208300445034 ); REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12 ( 0.00959063897026685 ); ----------------C3-------------- V$NERF_Q2 ( 0.000322490087919308 ); GGGCGGR_V$SP1_Q6 ( 0.000365882864465851 ); GGCAGAC,MIR-346 ( 0.00148726542410574 ); V$TEL2_Q6 ( 0.00498016827972087 ); RGTTAMWNATT_V$HNF1_01 ( 0.00630397230468749 ); V$LXR_Q3 ( 0.00698777810176837 ); V$MYB_Q6 ( 0.00882214144636585 ); ACTWSNACTNY_UNKNOWN ( 0.00888394760320588 ); ----------------C4-------------- MORF_AP2M1 ( 1.62910246916335e-07 ); MORF_DDB1 ( 3.90136970513631e-06 ); MORF_PRKAG1 ( 1.36023077960433e-05 ); MORF_GPX4 ( 0.000400056659999869 ); MORF_CSNK2B ( 0.000515665013897544 ); module_60 ( 0.000587575706929614 ); MORF_NME2 ( 0.000591292831972063 ); module_42 ( 0.000715105846246239 ); module_77 ( 0.00100285502957631 ); MORF_PHB ( 0.00116988302877669 ); MORF_AP3D1 ( 0.00159366961237257 ); MORF_ANP32B ( 0.00165878664592927 ); MORF_DAP ( 0.00171310636376747 ); MORF_SOD1 ( 0.001974690790788 ); MORF_RBBP8 ( 0.00224736782746029 ); MORF_TPR ( 0.00242740423419129 ); MORF_RAB5A ( 0.00275812649814569 ); MORF_DDX11 ( 0.00294606339417092 ); MORF_FDXR ( 0.00320945778975245 ); module_25 ( 0.00369672035303742 ); MORF_GNB1 ( 0.00379709620660605 ); module_22 ( 0.00397888236937925 ); MORF_FANCG ( 0.00398174407982126 ); MORF_USP5 ( 0.00423462579279568 ); MORF_TERF2IP ( 0.00541277006995731 ); MORF_HDAC1 ( 0.00541551233564324 ); MORF_PSMC1 ( 0.00583717820959829 ); MORF_SS18 ( 0.00664061714670043 ); ----------------C5-------------- PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY ( 0.000632563106717915 ); SIGNAL_TRANSDUCTION ( 0.000761185483116143 ); PROTEIN_METABOLIC_PROCESS ( 0.0019350742311021 ); INTRACELLULAR_SIGNALING_CASCADE ( 0.00205634074884003 ); CYTOPLASM ( 0.00219152291865487 ); PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY ( 0.0025213094873456 ); GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS ( 0.00326912383311879 ); RESPONSE_TO_OXIDATIVE_STRESS ( 0.00397888236937925 ); CELLULAR_PROTEIN_METABOLIC_PROCESS ( 0.00416953516195917 ); NADH_DEHYDROGENASE_COMPLEX ( 0.00429286978852534 ); MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I ( 0.00429286978852534 ); RESPIRATORY_CHAIN_COMPLEX_I ( 0.00429286978852534 ); CELL_SURFACE_RECEPTOR_LINKED_SIGNAL_TRANSDUCTION_GO_0007166 ( 0.00442778585589433 ); CELLULAR_MACROMOLECULE_METABOLIC_PROCESS ( 0.00471540469473267 ); GTPASE_ACTIVITY ( 0.00522229744586491 ); POST_TRANSLATIONAL_PROTEIN_MODIFICATION ( 0.00557651994867056 ); PHOSPHORIC_MONOESTER_HYDROLASE_ACTIVITY ( 0.00757789172676567 ); G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY ( 0.00815514357963378 ); POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION ( 0.0099568524345895 ); ----------------GOSLIM-------------- GO:0002478 antigen processing and presentation of exogenous peptide antigen ( 0.000447840175966972 ); GO:0002495 antigen processing and presentation of peptide antigen via MHC class II ( 0.000447840175966972 ); GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II ( 0.000447840175966972 ); GO:0048002 antigen processing and presentation of peptide antigen ( 0.000447840175966972 ); GO:0019882 antigen processing and presentation ( 0.000447840175966972 ); GO:0019884 antigen processing and presentation of exogenous antigen ( 0.000447840175966972 ); GO:0044444 cytoplasmic part ( 0.000447840175966972 ); GO:0030176 integral to endoplasmic reticulum membrane ( 0.000447840175966972 ); GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( 0.000447840175966972 ); GO:0005747 mitochondrial respiratory chain complex I ( 0.000447840175966972 ); GO:0030964 NADH dehydrogenase complex ( 0.000447840175966972 ); GO:0045271 respiratory chain complex I ( 0.000447840175966972 ); GO:0006793 phosphorus metabolic process ( 0.000447840175966972 ); GO:0006796 phosphate metabolic process ( 0.000447840175966972 ); GO:0003954 NADH dehydrogenase activity ( 0.000447840175966972 ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( 0.000447840175966972 ); GO:0050136 NADH dehydrogenase (quinone) activity ( 0.000447840175966972 ); GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor ( 0.000447840175966972 ); GO:0042773 ATP synthesis coupled electron transport ( 0.000447840175966972 ); GO:0042775 mitochondrial ATP synthesis coupled electron transport ( 0.000447840175966972 ); GO:0048869 cellular developmental process ( 0.000447840175966972 ); GO:0015457 auxiliary transport protein activity ( 0.000447840175966972 ); GO:0044267 cellular protein metabolic process ( 0.000447840175966972 ); GO:0022904 respiratory electron transport chain ( 0.000447840175966972 ); GO:0019538 protein metabolic process ( 0.000447840175966972 ); GO:0005829 cytosol ( 0.000447840175966972 ); GO:0031227 intrinsic to endoplasmic reticulum membrane ( 0.000447840175966972 ); GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ( 0.000447840175966972 ); GO:0035137 hindlimb morphogenesis ( 0.000447840175966972 ); GO:0006696 ergosterol biosynthetic process ( 0.000447840175966972 ); GO:0008204 ergosterol metabolic process ( 0.000447840175966972 ); GO:0021759 globus pallidus development ( 0.000447840175966972 ); GO:0021831 embryonic olfactory bulb interneuron precursor migration ( 0.000447840175966972 ); GO:0021889 olfactory bulb interneuron differentiation ( 0.000447840175966972 ); GO:0021891 olfactory bulb interneuron development ( 0.000447840175966972 ); GO:0022028 tangential migration from the subventricular zone to the olfactory bulb ( 0.000447840175966972 ); GO:0035120 post-embryonic appendage morphogenesis ( 0.000447840175966972 ); GO:0035127 post-embryonic limb morphogenesis ( 0.000447840175966972 ); GO:0035129 post-embryonic hindlimb morphogenesis ( 0.000447840175966972 ); GO:0050855 regulation of B cell receptor signaling pathway ( 0.000447840175966972 ); GO:0050861 positive regulation of B cell receptor signaling pathway ( 0.000447840175966972 ); GO:0002055 adenine binding ( 0.000447840175966972 ); GO:0003999 adenine phosphoribosyltransferase activity ( 0.000447840175966972 ); GO:0008389 coumarin 7-hydroxylase activity ( 0.000447840175966972 ); GO:0015367 oxoglutarate:malate antiporter activity ( 0.000447840175966972 ); GO:0031997 N-terminal myristoylation domain binding ( 0.000447840175966972 ); GO:0006903 vesicle targeting ( 0.000447840175966972 ); GO:0019370 leukotriene biosynthetic process ( 0.000447840175966972 ); GO:0022898 regulation of transmembrane transporter activity ( 0.000447840175966972 ); GO:0032409 regulation of transporter activity ( 0.000447840175966972 ); GO:0032412 regulation of ion transmembrane transporter activity ( 0.000447840175966972 ); GO:0043450 alkene biosynthetic process ( 0.000447840175966972 ); GO:0030154 cell differentiation ( 0.000447840175966972 ); GO:0016310 phosphorylation ( 0.000447840175966972 ); GO:0031090 organelle membrane ( 0.000447840175966972 ); GO:0007584 response to nutrient ( 0.000447840175966972 ); GO:0005925 focal adhesion ( 0.000447840175966972 ); GO:0005746 mitochondrial respiratory chain ( 0.000447840175966972 ); GO:0005924 cell-substrate adherens junction ( 0.000447840175966972 ); ----------------GO-------------- GO:0002478 antigen processing and presentation of exogenous peptide antigen ( 0.000491912432025428 ); GO:0002495 antigen processing and presentation of peptide antigen via MHC class II ( 0.000491912432025428 ); GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II ( 0.000491912432025428 ); GO:0048002 antigen processing and presentation of peptide antigen ( 0.000556369728241698 ); GO:0019882 antigen processing and presentation ( 0.000713892583216359 ); GO:0019884 antigen processing and presentation of exogenous antigen ( 0.00073443677438321 ); GO:0044444 cytoplasmic part ( 0.00190233172361202 ); GO:0030176 integral to endoplasmic reticulum membrane ( 0.00193233995689499 ); GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( 0.00209714884279017 ); GO:0005747 mitochondrial respiratory chain complex I ( 0.00209714884279017 ); GO:0030964 NADH dehydrogenase complex ( 0.00209714884279017 ); GO:0045271 respiratory chain complex I ( 0.00209714884279017 ); GO:0006793 phosphorus metabolic process ( 0.00214719131236145 ); GO:0006796 phosphate metabolic process ( 0.00214719131236145 ); GO:0003954 NADH dehydrogenase activity ( 0.00227043962357102 ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( 0.00227043962357102 ); GO:0050136 NADH dehydrogenase (quinone) activity ( 0.00227043962357102 ); GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor ( 0.00305130134174511 ); GO:0042773 ATP synthesis coupled electron transport ( 0.0037327943090346 ); GO:0042775 mitochondrial ATP synthesis coupled electron transport ( 0.0037327943090346 ); GO:0048869 cellular developmental process ( 0.00390199808525138 ); GO:0015457 auxiliary transport protein activity ( 0.00397888236937925 ); GO:0044267 cellular protein metabolic process ( 0.00456663018814857 ); GO:0022904 respiratory electron transport chain ( 0.00506087208405462 ); GO:0019538 protein metabolic process ( 0.0051730272771286 ); GO:0005829 cytosol ( 0.00522338522763532 ); GO:0031227 intrinsic to endoplasmic reticulum membrane ( 0.00535630206153778 ); GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ( 0.00560866637095689 ); GO:0035137 hindlimb morphogenesis ( 0.00560866637095689 ); GO:0006696 ergosterol biosynthetic process ( 0.0070879203740013 ); GO:0008204 ergosterol metabolic process ( 0.0070879203740013 ); GO:0021759 globus pallidus development ( 0.0070879203740013 ); GO:0021831 embryonic olfactory bulb interneuron precursor migration ( 0.0070879203740013 ); GO:0021889 olfactory bulb interneuron differentiation ( 0.0070879203740013 ); GO:0021891 olfactory bulb interneuron development ( 0.0070879203740013 ); GO:0022028 tangential migration from the subventricular zone to the olfactory bulb ( 0.0070879203740013 ); GO:0035120 post-embryonic appendage morphogenesis ( 0.0070879203740013 ); GO:0035127 post-embryonic limb morphogenesis ( 0.0070879203740013 ); GO:0035129 post-embryonic hindlimb morphogenesis ( 0.0070879203740013 ); GO:0050855 regulation of B cell receptor signaling pathway ( 0.0070879203740013 ); GO:0050861 positive regulation of B cell receptor signaling pathway ( 0.0070879203740013 ); GO:0002055 adenine binding ( 0.0070879203740013 ); GO:0003999 adenine phosphoribosyltransferase activity ( 0.0070879203740013 ); GO:0008389 coumarin 7-hydroxylase activity ( 0.0070879203740013 ); GO:0015367 oxoglutarate:malate antiporter activity ( 0.0070879203740013 ); GO:0031997 N-terminal myristoylation domain binding ( 0.0070879203740013 ); GO:0006903 vesicle targeting ( 0.00788208300445034 ); GO:0019370 leukotriene biosynthetic process ( 0.00788208300445034 ); GO:0022898 regulation of transmembrane transporter activity ( 0.00788208300445034 ); GO:0032409 regulation of transporter activity ( 0.00788208300445034 ); GO:0032412 regulation of ion transmembrane transporter activity ( 0.00788208300445034 ); GO:0043450 alkene biosynthetic process ( 0.00788208300445034 ); GO:0030154 cell differentiation ( 0.0079218099913595 ); GO:0016310 phosphorylation ( 0.00838856498930827 ); GO:0031090 organelle membrane ( 0.00872573449641711 ); GO:0007584 response to nutrient ( 0.00888394760320588 ); GO:0005925 focal adhesion ( 0.00929573423890937 ); GO:0005746 mitochondrial respiratory chain ( 0.00971851721439173 ); GO:0005924 cell-substrate adherens junction ( 0.00971851721439173 ); ----------------KEGG-------------- hsa04510 Focal adhesion ( 0.000534788913552973 ); hsa05211 Renal cell carcinoma ( 0.00146328012712838 ); hsa05010 Alzheimer's disease ( 0.00554077640621086 ); hsa04360 Axon guidance ( 0.013462669892133 ); hsa04720 Long-term potentiation ( 0.014026744475264 ); hsa05212 Pancreatic cancer ( 0.0145621200453291 ); hsa04810 Regulation of actin cytoskeleton ( 0.0170243974328025 ); hsa04350 TGF-beta signaling pathway ( 0.0232699049605943 ); hsa05219 Bladder cancer ( 0.0357053217545 ); hsa04916 Melanogenesis ( 0.0360040794192123 ); hsa04150 mTOR signaling pathway ( 0.0438182279756965 ); hsa05012 Parkinson's disease ( 0.0464505997359535 ); hsa00190 Oxidative phosphorylation ( 0.0474669113184959 ); hsa00232 Caffeine metabolism ( 0.0485799780590498 ); ----------------CARTA-------------- skp2e2fpathway ( 0.028053764550949 ); extrinsicpathway ( 0.028053764550949 ); vifpathway ( 0.0349442275806797 ); prc2pathway ( 0.0349442275806797 ); erkpathway ( 0.0349442275806797 ); p38mapkpathway ( 0.0357053217545 ); fbw7pathway ( 0.0417861857419389 ); p27pathway ( 0.0485799780590498 ); ----------------RBP-------------- AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 1.6741376335955e-09 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 1.03744799819302e-08 ); AGO2_PAR-CLIP_(Kishore_2011) ( 1.06211115902994e-08 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 8.35243737192499e-08 ); ELAVL1_CLIP-SEQ_(Kishore_2011) ( 0.00128210290982341 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00214918842350866 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.00701244427772392 ); ----------------immu-------------- ( 0.00333355114263546 ); ----------------ARE-------------- ( ); ============================ group10 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$HEB_Q6 ( 0.00206411872727607 ); GTACTGT,MIR-101 ( 0.00373957980957067 ); V$LEF1_Q2 ( 0.00506481489102905 ); V$AP4_Q6 ( 0.00532687021008668 ); V$SREBP_Q3 ( 0.00777870260228296 ); TGACCTTG_V$SF1_Q6 ( 0.00795408880257766 ); V$SF1_Q6 ( 0.00831308135056152 ); ----------------C4-------------- ( 0.00500684178910281 ); ----------------C5-------------- HYDROLASE_ACTIVITY__ACTING_ON_ACID_ANHYDRIDES__CATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES ( 0.0022393732544492 ); PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00240920299665768 ); ATPASE_ACTIVITY__COUPLED_TO_MOVEMENT_OF_SUBSTANCES ( 0.00240920299665768 ); ----------------GOSLIM-------------- GO:0005697 telomerase holoenzyme complex ( 0.00479996705751333 ); GO:0005578 proteinaceous extracellular matrix ( 0.00904543746986282 ); GO:0031012 extracellular matrix ( 0.00479996705751333 ); GO:0000722 telomere maintenance via recombination ( 0.00904543746986282 ); GO:0006196 AMP catabolic process ( 0.00479996705751333 ); GO:0009125 nucleoside monophosphate catabolic process ( 0.00904543746986282 ); GO:0009128 purine nucleoside monophosphate catabolic process ( 0.00479996705751333 ); GO:0009158 ribonucleoside monophosphate catabolic process ( 0.00904543746986282 ); GO:0009169 purine ribonucleoside monophosphate catabolic process ( 0.00479996705751333 ); GO:0021703 locus ceruleus development ( 0.00904543746986282 ); GO:0030037 actin filament reorganization during cell cycle ( 0.00479996705751333 ); GO:0051823 regulation of synapse structural plasticity ( 0.00904543746986282 ); GO:0009673 low affinity phosphate transmembrane transporter activity ( 0.00479996705751333 ); GO:0009917 sterol 5-alpha reductase activity ( 0.00904543746986282 ); GO:0015633 zinc transporting ATPase activity ( 0.00479996705751333 ); GO:0043890 N-acetylgalactosamine-6-sulfatase activity ( 0.00904543746986282 ); GO:0050265 RNA uridylyltransferase activity ( 0.00479996705751333 ); GO:0005891 voltage-gated calcium channel complex ( 0.00904543746986282 ); GO:0032403 protein complex binding ( 0.00479996705751333 ); ----------------GO-------------- GO:0005697 telomerase holoenzyme complex ( 0.000437841337863313 ); GO:0005578 proteinaceous extracellular matrix ( 0.00339949315808972 ); GO:0031012 extracellular matrix ( 0.00439544766775135 ); GO:0000722 telomere maintenance via recombination ( 0.00668576886341921 ); GO:0006196 AMP catabolic process ( 0.00668576886341921 ); GO:0009125 nucleoside monophosphate catabolic process ( 0.00668576886341921 ); GO:0009128 purine nucleoside monophosphate catabolic process ( 0.00668576886341921 ); GO:0009158 ribonucleoside monophosphate catabolic process ( 0.00668576886341921 ); GO:0009169 purine ribonucleoside monophosphate catabolic process ( 0.00668576886341921 ); GO:0021703 locus ceruleus development ( 0.00668576886341921 ); GO:0030037 actin filament reorganization during cell cycle ( 0.00668576886341921 ); GO:0051823 regulation of synapse structural plasticity ( 0.00668576886341921 ); GO:0009673 low affinity phosphate transmembrane transporter activity ( 0.00668576886341921 ); GO:0009917 sterol 5-alpha reductase activity ( 0.00668576886341921 ); GO:0015633 zinc transporting ATPase activity ( 0.00668576886341921 ); GO:0043890 N-acetylgalactosamine-6-sulfatase activity ( 0.00668576886341921 ); GO:0050265 RNA uridylyltransferase activity ( 0.00668576886341921 ); GO:0005891 voltage-gated calcium channel complex ( 0.00857286987185933 ); GO:0032403 protein complex binding ( 0.0086355849377486 ); ----------------KEGG-------------- hsa00150 Androgen and estrogen metabolism ( 0.0293240443432064 ); hsa02010 ABC transporters - General ( 0.0349570768392989 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2981 ========================= ----------------C2-------------- KEGG_PROTEIN_EXPORT ( 0.00502473806660315 ); KEGG_MISMATCH_REPAIR ( 0.00502473806660315 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_RAD23A ( 0.00067242529657006 ); MORF_RAD21 ( 0.000790113639246789 ); MORF_RAD23B ( 0.000813160178548522 ); GNF2_S100A4 ( 0.00103324424285847 ); GNF2_PECAM1 ( 0.00160314318772916 ); GNF2_ITGB2 ( 0.0020019442173024 ); GNF2_TNFRSF1B ( 0.00270732142234626 ); GNF2_BUB3 ( 0.00460158942920783 ); module_82 ( 0.00546511698662106 ); module_371 ( 0.00592256131614645 ); MORF_BUB3 ( 0.00706029879124579 ); module_281 ( 0.00739565490286539 ); GNF2_HCK ( 0.0079119681385504 ); GNF2_FGR ( 0.00901650922038195 ); MORF_SKP1A ( 0.00904576111030175 ); MORF_GNB1 ( 0.00956022119451124 ); GNF2_PCAF ( 0.00958888883761253 ); ----------------C5-------------- PROTEIN_AMINO_ACID_AUTOPHOSPHORYLATION ( 0.00846007209730305 ); PROTEIN_AUTOPROCESSING ( 0.00901650922038195 ); GROWTH_FACTOR_BINDING ( 0.00901650922038195 ); ----------------GOSLIM-------------- GO:0051656 establishment of organelle localization ( ); GO:0051640 organelle localization ( ); GO:0006890 retrograde vesicle-mediated transport, Golgi to ER ( ); GO:0001802 type III hypersensitivity ( ); GO:0001803 regulation of type III hypersensitivity ( ); GO:0001805 positive regulation of type III hypersensitivity ( ); GO:0033026 negative regulation of mast cell apoptosis ( ); GO:0033182 regulation of histone ubiquitination ( ); GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I ( ); GO:0045993 negative regulation of translational initiation by iron ( ); GO:0004506 squalene monooxygenase activity ( ); GO:0005139 interleukin-7 receptor binding ( ); GO:0048408 epidermal growth factor binding ( ); GO:0050353 trimethyllysine dioxygenase activity ( ); GO:0002429 immune response-activating cell surface receptor signaling pathway ( ); GO:0002768 immune response-regulating cell surface receptor signaling pathway ( ); GO:0051650 establishment of vesicle localization ( ); GO:0051648 vesicle localization ( ); GO:0048193 Golgi vesicle transport ( ); GO:0002757 immune response-activating signal transduction ( ); GO:0002764 immune response-regulating signal transduction ( ); GO:0000729 DNA double-strand break processing ( ); GO:0001794 type IIa hypersensitivity ( ); GO:0001796 regulation of type IIa hypersensitivity ( ); GO:0001798 positive regulation of type IIa hypersensitivity ( ); GO:0001810 regulation of type I hypersensitivity ( ); GO:0001812 positive regulation of type I hypersensitivity ( ); GO:0002431 Fc receptor mediated stimulatory signaling pathway ( ); GO:0002445 type II hypersensitivity ( ); GO:0002888 positive regulation of myeloid leukocyte mediated immunity ( ); GO:0002892 regulation of type II hypersensitivity ( ); GO:0002894 positive regulation of type II hypersensitivity ( ); GO:0006447 regulation of translational initiation by iron ( ); GO:0016068 type I hypersensitivity ( ); GO:0016090 prenol metabolic process ( ); GO:0016093 polyprenol metabolic process ( ); GO:0019348 dolichol metabolic process ( ); GO:0032765 positive regulation of mast cell cytokine production ( ); GO:0033023 mast cell homeostasis ( ); GO:0033024 mast cell apoptosis ( ); GO:0033025 regulation of mast cell apoptosis ( ); GO:0045329 carnitine biosynthetic process ( ); GO:0031094 platelet dense tubular network ( ); GO:0031372 UBC13-MMS2 complex ( ); GO:0032997 Fc receptor complex ( ); GO:0032998 Fc-epsilon receptor I complex ( ); GO:0033185 dolichol-phosphate-mannose synthase complex ( ); GO:0004914 interleukin-5 receptor activity ( ); GO:0019767 IgE receptor activity ( ); GO:0019980 interleukin-5 binding ( ); ----------------GO-------------- GO:0051656 establishment of organelle localization ( 0.0013396016400879 ); GO:0051640 organelle localization ( 0.00245747122525543 ); GO:0006890 retrograde vesicle-mediated transport, Golgi to ER ( 0.00308463500996773 ); GO:0001802 type III hypersensitivity ( 0.00462474237168853 ); GO:0001803 regulation of type III hypersensitivity ( 0.00462474237168853 ); GO:0001805 positive regulation of type III hypersensitivity ( 0.00462474237168853 ); GO:0033026 negative regulation of mast cell apoptosis ( 0.00462474237168853 ); GO:0033182 regulation of histone ubiquitination ( 0.00462474237168853 ); GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I ( 0.00462474237168853 ); GO:0045993 negative regulation of translational initiation by iron ( 0.00462474237168853 ); GO:0004506 squalene monooxygenase activity ( 0.00462474237168853 ); GO:0005139 interleukin-7 receptor binding ( 0.00462474237168853 ); GO:0048408 epidermal growth factor binding ( 0.00462474237168853 ); GO:0050353 trimethyllysine dioxygenase activity ( 0.00462474237168853 ); GO:0002429 immune response-activating cell surface receptor signaling pathway ( 0.00592256131614645 ); GO:0002768 immune response-regulating cell surface receptor signaling pathway ( 0.00639690730956514 ); GO:0051650 establishment of vesicle localization ( 0.00688799234204692 ); GO:0051648 vesicle localization ( 0.00739565490286539 ); GO:0048193 Golgi vesicle transport ( 0.00742768586589165 ); GO:0002757 immune response-activating signal transduction ( 0.00791973458875474 ); GO:0002764 immune response-regulating signal transduction ( 0.00846007209730305 ); GO:0000729 DNA double-strand break processing ( 0.00922832791873329 ); GO:0001794 type IIa hypersensitivity ( 0.00922832791873329 ); GO:0001796 regulation of type IIa hypersensitivity ( 0.00922832791873329 ); GO:0001798 positive regulation of type IIa hypersensitivity ( 0.00922832791873329 ); GO:0001810 regulation of type I hypersensitivity ( 0.00922832791873329 ); GO:0001812 positive regulation of type I hypersensitivity ( 0.00922832791873329 ); GO:0002431 Fc receptor mediated stimulatory signaling pathway ( 0.00922832791873329 ); GO:0002445 type II hypersensitivity ( 0.00922832791873329 ); GO:0002888 positive regulation of myeloid leukocyte mediated immunity ( 0.00922832791873329 ); GO:0002892 regulation of type II hypersensitivity ( 0.00922832791873329 ); GO:0002894 positive regulation of type II hypersensitivity ( 0.00922832791873329 ); GO:0006447 regulation of translational initiation by iron ( 0.00922832791873329 ); GO:0016068 type I hypersensitivity ( 0.00922832791873329 ); GO:0016090 prenol metabolic process ( 0.00922832791873329 ); GO:0016093 polyprenol metabolic process ( 0.00922832791873329 ); GO:0019348 dolichol metabolic process ( 0.00922832791873329 ); GO:0032765 positive regulation of mast cell cytokine production ( 0.00922832791873329 ); GO:0033023 mast cell homeostasis ( 0.00922832791873329 ); GO:0033024 mast cell apoptosis ( 0.00922832791873329 ); GO:0033025 regulation of mast cell apoptosis ( 0.00922832791873329 ); GO:0045329 carnitine biosynthetic process ( 0.00922832791873329 ); GO:0031094 platelet dense tubular network ( 0.00922832791873329 ); GO:0031372 UBC13-MMS2 complex ( 0.00922832791873329 ); GO:0032997 Fc receptor complex ( 0.00922832791873329 ); GO:0032998 Fc-epsilon receptor I complex ( 0.00922832791873329 ); GO:0033185 dolichol-phosphate-mannose synthase complex ( 0.00922832791873329 ); GO:0004914 interleukin-5 receptor activity ( 0.00922832791873329 ); GO:0019767 IgE receptor activity ( 0.00922832791873329 ); GO:0019980 interleukin-5 binding ( 0.00922832791873329 ); ----------------KEGG-------------- hsa03430 Mismatch repair ( 0.00502473806660315 ); hsa04120 Ubiquitin mediated proteolysis ( 0.0229147612129258 ); hsa00900 Terpenoid biosynthesis ( 0.0274330099951938 ); hsa04060 Cytokine-cytokine receptor interaction ( 0.0306668224514731 ); hsa03060 Protein export ( 0.0453067644227831 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0483548896603272 ); ----------------CARTA-------------- plcdpathway ( 0.0183724110202476 ); plateletapppathway ( 0.0274330099951938 ); vobesitypathway ( 0.0274330099951938 ); ifngpathway ( 0.0364108787411853 ); hifpathway ( 0.0497241952769356 ); ----------------RBP-------------- AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0108734206557309 ); ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.0120403267893723 ); ELAVL1_CLIP-SEQ_(Kishore_2011) ( 0.0122814089285657 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0126814767265951 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0429582444088847 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group11 ========================= ----------------C2-------------- ( 0.00809697451029487 ); ----------------C3-------------- V$AP2_Q6_01 ( 0.00116455134544272 ); CAGGTCC,MIR-492 ( 0.00121223053844699 ); CACTGTG,MIR-128A,MIR-128B ( 0.00133329744634464 ); V$SRY_02 ( 0.00147937428308537 ); V$DBP_Q6 ( 0.00154918765213014 ); V$PAX5_01 ( 0.00157941066574199 ); V$SOX5_01 ( 0.00158499029803464 ); TTGGAGA,MIR-515-5P,MIR-519E ( 0.00190614488902958 ); V$GATA_C ( 0.00193520959236608 ); GAGCCTG,MIR-484 ( 0.00636680249145188 ); TGAGATT,MIR-216 ( 0.00699915728484927 ); CTCAGGG,MIR-125B,MIR-125A ( 0.00726870287056339 ); V$HMGIY_Q6 ( 0.00836776456120499 ); V$GATA4_Q3 ( 0.00852674929785114 ); GCANCTGNY_V$MYOD_Q6 ( 0.00853337667109636 ); AAAYRNCTG_UNKNOWN ( 0.00877106411987754 ); CAGCTG_V$AP4_Q5 ( 0.00897230811196685 ); V$AP2_Q6 ( 0.00935140005818341 ); AACTGGA,MIR-145 ( 0.00952234165443236 ); ----------------C4-------------- module_13 ( 5.78746045333883e-05 ); module_18 ( 0.000615059269736248 ); module_41 ( 0.0023340732351221 ); module_104 ( 0.00335939058475035 ); MORF_PDCD1 ( 0.0034377132099257 ); module_226 ( 0.00618145218955928 ); MORF_CASP2 ( 0.00636680249145188 ); module_281 ( 0.00663813676749491 ); module_11 ( 0.00743718153235173 ); MORF_CNTN1 ( 0.00766755661449325 ); module_66 ( 0.00814087100834602 ); MORF_PTPRR ( 0.00886290526997151 ); module_52 ( 0.00929216027285372 ); module_153 ( 0.00968616255143216 ); ----------------C5-------------- TISSUE_DEVELOPMENT ( 0.00308100529432333 ); EPIDERMIS_DEVELOPMENT ( 0.00358039794599907 ); PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY ( 0.00490209710301536 ); SOLUBLE_FRACTION ( 0.00500343092430214 ); ECTODERM_DEVELOPMENT ( 0.00502857483718442 ); GOLGI_APPARATUS_PART ( 0.00911431880553114 ); ----------------GOSLIM-------------- GO:0015826 threonine transport ( 0.00943127219383938 ); GO:0034589 hydroxyproline transport ( 0.00943127219383938 ); GO:0042766 nucleosome mobilization ( 0.00943127219383938 ); GO:0043133 hindgut contraction ( 0.00943127219383938 ); GO:0043134 regulation of hindgut contraction ( 0.00943127219383938 ); GO:0001616 growth hormone secretagogue receptor activity ( 0.00943127219383938 ); GO:0015195 L-threonine transmembrane transporter activity ( 0.00943127219383938 ); GO:0016843 amine-lyase activity ( 0.00943127219383938 ); GO:0016844 strictosidine synthase activity ( 0.00943127219383938 ); GO:0034590 L-hydroxyproline transmembrane transporter activity ( 0.00943127219383938 ); GO:0016790 thiolester hydrolase activity ( 0.00943127219383938 ); GO:0019233 sensory perception of pain ( 0.00943127219383938 ); GO:0015837 amine transport ( 0.00943127219383938 ); GO:0007270 nerve-nerve synaptic transmission ( 0.00943127219383938 ); GO:0006003 fructose 2,6-bisphosphate metabolic process ( 0.00943127219383938 ); GO:0015825 L-serine transport ( 0.00943127219383938 ); GO:0016266 O-glycan processing ( 0.00943127219383938 ); GO:0032226 positive regulation of synaptic transmission, dopaminergic ( 0.00943127219383938 ); GO:0033603 positive regulation of dopamine secretion ( 0.00943127219383938 ); GO:0046498 S-adenosylhomocysteine metabolic process ( 0.00943127219383938 ); GO:0004021 alanine transaminase activity ( 0.00943127219383938 ); GO:0008119 thiopurine S-methyltransferase activity ( 0.00943127219383938 ); GO:0008474 palmitoyl-(protein) hydrolase activity ( 0.00943127219383938 ); GO:0015181 arginine transmembrane transporter activity ( 0.00943127219383938 ); GO:0046922 peptide-O-fucosyltransferase activity ( 0.00943127219383938 ); GO:0044431 Golgi apparatus part ( 0.00943127219383938 ); GO:0015179 L-amino acid transmembrane transporter activity ( 0.00943127219383938 ); ----------------GO-------------- GO:0015826 threonine transport ( 0.00437339767757505 ); GO:0034589 hydroxyproline transport ( 0.00437339767757505 ); GO:0042766 nucleosome mobilization ( 0.00437339767757505 ); GO:0043133 hindgut contraction ( 0.00437339767757505 ); GO:0043134 regulation of hindgut contraction ( 0.00437339767757505 ); GO:0001616 growth hormone secretagogue receptor activity ( 0.00437339767757505 ); GO:0015195 L-threonine transmembrane transporter activity ( 0.00437339767757505 ); GO:0016843 amine-lyase activity ( 0.00437339767757505 ); GO:0016844 strictosidine synthase activity ( 0.00437339767757505 ); GO:0034590 L-hydroxyproline transmembrane transporter activity ( 0.00437339767757505 ); GO:0016790 thiolester hydrolase activity ( 0.00520817001465046 ); GO:0019233 sensory perception of pain ( 0.00531329426277262 ); GO:0015837 amine transport ( 0.00789844800879177 ); GO:0007270 nerve-nerve synaptic transmission ( 0.00809697451029487 ); GO:0006003 fructose 2,6-bisphosphate metabolic process ( 0.00872788764349375 ); GO:0015825 L-serine transport ( 0.00872788764349375 ); GO:0016266 O-glycan processing ( 0.00872788764349375 ); GO:0032226 positive regulation of synaptic transmission, dopaminergic ( 0.00872788764349375 ); GO:0033603 positive regulation of dopamine secretion ( 0.00872788764349375 ); GO:0046498 S-adenosylhomocysteine metabolic process ( 0.00872788764349375 ); GO:0004021 alanine transaminase activity ( 0.00872788764349375 ); GO:0008119 thiopurine S-methyltransferase activity ( 0.00872788764349375 ); GO:0008474 palmitoyl-(protein) hydrolase activity ( 0.00872788764349375 ); GO:0015181 arginine transmembrane transporter activity ( 0.00872788764349375 ); GO:0046922 peptide-O-fucosyltransferase activity ( 0.00872788764349375 ); GO:0044431 Golgi apparatus part ( 0.00960962586790805 ); GO:0015179 L-amino acid transmembrane transporter activity ( 0.00968616255143216 ); ----------------KEGG-------------- hsa00561 Glycerolipid metabolism ( 0.0202187993738326 ); hsa00053 Ascorbate and aldarate metabolism ( 0.0386866457050762 ); hsa00062 Fatty acid elongation in mitochondria ( 0.0428927542256788 ); ----------------CARTA-------------- ( 0.00872788764349375 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00617869043165894 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.00630503321754072 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group13 ========================= ----------------C2-------------- REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS ( 3.61406125621404e-05 ); REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING ( 5.9078695474075e-05 ); REACTOME_LYSOSOME_VESICLE_BIOGENESIS ( 7.02577998859902e-05 ); REACTOME_MEMBRANE_TRAFFICKING ( 0.000156742332514389 ); REACTOME_GAP_JUNCTION_DEGRADATION ( 0.000539337239321778 ); REACTOME_METABOLISM_OF_NITRIC_OXIDE ( 0.00092848818323316 ); REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL ( 0.00108077417908612 ); KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES ( 0.00124421348726135 ); REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY ( 0.00162921195519091 ); REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING ( 0.00200794747832779 ); KEGG_VEGF_SIGNALING_PATHWAY ( 0.00235048230626851 ); REACTOME_CTLA4_INHIBITORY_SIGNALING ( 0.00245472214861611 ); REACTOME_COLLAGEN_MEDIATED_ACTIVATION_CASCADE ( 0.002943956387775 ); REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA ( 0.00347504879914701 ); REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING ( 0.00434887104297897 ); REACTOME_GAP_JUNCTION_TRAFFICKING ( 0.00434887104297897 ); KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS ( 0.004582934641455 ); REACTOME_CD28_CO_STIMULATION ( 0.00466043322236566 ); REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE ( 0.00573974351269187 ); REACTOME_SIGNALLING_BY_NGF ( 0.00697502521189125 ); REACTOME_PI3K_AKT_SIGNALLING ( 0.00750771409424377 ); ----------------C3-------------- V$FAC1_01 ( 0.0022326006045414 ); RACCACAR_V$AML_Q6 ( 0.0042771477094069 ); ----------------C4-------------- module_98 ( 0.000374307796780803 ); module_177 ( 0.000443848334929066 ); module_257 ( 0.00138848546422907 ); MORF_PHB ( 0.00705684018778446 ); ----------------C5-------------- GLYCOSPHINGOLIPID_METABOLIC_PROCESS ( 0.000787434015709663 ); GLYCOLIPID_METABOLIC_PROCESS ( 0.00141872799153841 ); PROTEIN_KINASE_ACTIVITY ( 0.00287802698870905 ); SPHINGOLIPID_METABOLIC_PROCESS ( 0.00434887104297897 ); PROTEIN_MODIFICATION_PROCESS ( 0.00541285346108822 ); POST_TRANSLATIONAL_PROTEIN_MODIFICATION ( 0.00557129256266615 ); PHOSPHOTRANSFERASE_ACTIVITY__ALCOHOL_GROUP_AS_ACCEPTOR ( 0.00566905666454604 ); BIOPOLYMER_MODIFICATION ( 0.00627236435939956 ); KINASE_ACTIVITY ( 0.00845049168401132 ); PROTEIN_UBIQUITINATION ( 0.00873337715251606 ); CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY ( 0.00873337715251606 ); ----------------GOSLIM-------------- GO:0045787 positive regulation of cell cycle ( 6.46956567480566e-05 ); GO:0006688 glycosphingolipid biosynthetic process ( 0.000214896081660885 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00161002327451014 ); GO:0043227 membrane-bounded organelle ( 0.00471885134429305 ); GO:0009247 glycolipid biosynthetic process ( 0.00490092339502792 ); GO:0005622 intracellular ( 0.00565580708574913 ); GO:0006687 glycosphingolipid metabolic process ( 6.46956567480566e-05 ); GO:0044424 intracellular part ( 0.000214896081660885 ); GO:0030148 sphingolipid biosynthetic process ( 0.00161002327451014 ); GO:0006511 ubiquitin-dependent protein catabolic process ( 0.00471885134429305 ); GO:0019941 modification-dependent protein catabolic process ( 0.00490092339502792 ); GO:0043632 modification-dependent macromolecule catabolic process ( 0.00565580708574913 ); GO:0051603 proteolysis involved in cellular protein catabolic process ( 6.46956567480566e-05 ); GO:0034962 cellular biopolymer catabolic process ( 0.000214896081660885 ); GO:0044257 cellular protein catabolic process ( 0.00161002327451014 ); GO:0043229 intracellular organelle ( 0.00471885134429305 ); GO:0043226 organelle ( 0.00490092339502792 ); GO:0030163 protein catabolic process ( 0.00565580708574913 ); GO:0006858 extracellular transport ( 6.46956567480566e-05 ); GO:0006860 extracellular amino acid transport ( 0.000214896081660885 ); GO:0016480 negative regulation of transcription from RNA polymerase III promoter ( 0.00161002327451014 ); GO:0019042 latent virus infection ( 0.00471885134429305 ); GO:0019046 reactivation of latent virus ( 0.00490092339502792 ); GO:0002102 podosome ( 0.00565580708574913 ); GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity ( 6.46956567480566e-05 ); GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity ( 0.000214896081660885 ); GO:0004503 monophenol monooxygenase activity ( 0.00161002327451014 ); GO:0004617 phosphoglycerate dehydrogenase activity ( 0.00471885134429305 ); GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity ( 0.00490092339502792 ); GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity ( 0.00565580708574913 ); GO:0006664 glycolipid metabolic process ( 6.46956567480566e-05 ); GO:0009408 response to heat ( 0.000214896081660885 ); GO:0016567 protein ubiquitination ( 0.00161002327451014 ); GO:0032446 protein modification by small protein conjugation ( 0.00471885134429305 ); GO:0031301 integral to organelle membrane ( 0.00490092339502792 ); GO:0005794 Golgi apparatus ( 0.00565580708574913 ); GO:0001574 ganglioside biosynthetic process ( 6.46956567480566e-05 ); GO:0006494 protein amino acid terminal glycosylation ( 0.000214896081660885 ); GO:0006496 protein amino acid terminal N-glycosylation ( 0.00161002327451014 ); GO:0032469 endoplasmic reticulum calcium ion homeostasis ( 0.00471885134429305 ); GO:0034605 cellular response to heat ( 0.00490092339502792 ); GO:0004475 mannose-1-phosphate guanylyltransferase activity ( 0.00565580708574913 ); GO:0004839 ubiquitin activating enzyme activity ( 6.46956567480566e-05 ); GO:0008905 mannose-phosphate guanylyltransferase activity ( 0.000214896081660885 ); GO:0043008 ATP-dependent protein binding ( 0.00161002327451014 ); GO:0046978 TAP1 binding ( 0.00471885134429305 ); GO:0043285 biopolymer catabolic process ( 0.00490092339502792 ); GO:0030173 integral to Golgi membrane ( 0.00565580708574913 ); GO:0031300 intrinsic to organelle membrane ( 6.46956567480566e-05 ); GO:0009987 cellular process ( 0.000214896081660885 ); ----------------GO-------------- GO:0045787 positive regulation of cell cycle ( 0.000375513211779944 ); GO:0006688 glycosphingolipid biosynthetic process ( 0.0004324536774936 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00102813420259299 ); GO:0043227 membrane-bounded organelle ( 0.00103745065372038 ); GO:0009247 glycolipid biosynthetic process ( 0.00108077417908612 ); GO:0005622 intracellular ( 0.00122478021587297 ); GO:0006687 glycosphingolipid metabolic process ( 0.00180067211179996 ); GO:0044424 intracellular part ( 0.00195365968451116 ); GO:0030148 sphingolipid biosynthetic process ( 0.00245472214861611 ); GO:0006511 ubiquitin-dependent protein catabolic process ( 0.00260487810374126 ); GO:0019941 modification-dependent protein catabolic process ( 0.00263232236265258 ); GO:0043632 modification-dependent macromolecule catabolic process ( 0.00263232236265258 ); GO:0051603 proteolysis involved in cellular protein catabolic process ( 0.00263232236265258 ); GO:0034962 cellular biopolymer catabolic process ( 0.00268788027976619 ); GO:0044257 cellular protein catabolic process ( 0.00268788027976619 ); GO:0043229 intracellular organelle ( 0.00280390683543143 ); GO:0043226 organelle ( 0.00282637721993162 ); GO:0030163 protein catabolic process ( 0.00346150655231957 ); GO:0006858 extracellular transport ( 0.0035188257175891 ); GO:0006860 extracellular amino acid transport ( 0.0035188257175891 ); GO:0016480 negative regulation of transcription from RNA polymerase III promoter ( 0.0035188257175891 ); GO:0019042 latent virus infection ( 0.0035188257175891 ); GO:0019046 reactivation of latent virus ( 0.0035188257175891 ); GO:0002102 podosome ( 0.0035188257175891 ); GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity ( 0.0035188257175891 ); GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity ( 0.0035188257175891 ); GO:0004503 monophenol monooxygenase activity ( 0.0035188257175891 ); GO:0004617 phosphoglycerate dehydrogenase activity ( 0.0035188257175891 ); GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity ( 0.0035188257175891 ); GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity ( 0.0035188257175891 ); GO:0006664 glycolipid metabolic process ( 0.00404740413110028 ); GO:0009408 response to heat ( 0.00404740413110028 ); GO:0016567 protein ubiquitination ( 0.00444931367058049 ); GO:0032446 protein modification by small protein conjugation ( 0.00543573454335479 ); GO:0031301 integral to organelle membrane ( 0.00543573454335479 ); GO:0005794 Golgi apparatus ( 0.0067072340347822 ); GO:0001574 ganglioside biosynthetic process ( 0.00702544557480689 ); GO:0006494 protein amino acid terminal glycosylation ( 0.00702544557480689 ); GO:0006496 protein amino acid terminal N-glycosylation ( 0.00702544557480689 ); GO:0032469 endoplasmic reticulum calcium ion homeostasis ( 0.00702544557480689 ); GO:0034605 cellular response to heat ( 0.00702544557480689 ); GO:0004475 mannose-1-phosphate guanylyltransferase activity ( 0.00702544557480689 ); GO:0004839 ubiquitin activating enzyme activity ( 0.00702544557480689 ); GO:0008905 mannose-phosphate guanylyltransferase activity ( 0.00702544557480689 ); GO:0043008 ATP-dependent protein binding ( 0.00702544557480689 ); GO:0046978 TAP1 binding ( 0.00702544557480689 ); GO:0043285 biopolymer catabolic process ( 0.00822808611954356 ); GO:0030173 integral to Golgi membrane ( 0.00873337715251606 ); GO:0031300 intrinsic to organelle membrane ( 0.00893642471248998 ); GO:0009987 cellular process ( 0.00973024399190603 ); ----------------KEGG-------------- hsa00604 Glycosphingolipid biosynthesis - ganglio series ( 0.00141872799153841 ); hsa04370 VEGF signaling pathway ( 0.00217586219868018 ); hsa04120 Ubiquitin mediated proteolysis ( 0.0110828761450453 ); hsa04150 mTOR signaling pathway ( 0.0119137483152197 ); hsa05213 Endometrial cancer ( 0.0144500838335439 ); hsa05223 Non-small cell lung cancer ( 0.0155242240796795 ); hsa05221 Acute myeloid leukemia ( 0.0166316537765126 ); hsa04630 Jak-STAT signaling pathway ( 0.0167745843948736 ); hsa00950 Alkaloid biosynthesis I ( 0.0174724865552893 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0207625439918366 ); hsa05214 Glioma ( 0.0213842117795683 ); hsa04662 B cell receptor signaling pathway ( 0.0220135815721004 ); hsa04920 Adipocytokine signaling pathway ( 0.0226505931226288 ); hsa05211 Renal cell carcinoma ( 0.0246068806142761 ); hsa05218 Melanoma ( 0.0259481907808364 ); hsa05212 Pancreatic cancer ( 0.0266298053994057 ); hsa05220 Chronic myeloid leukemia ( 0.0280146634487377 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0294279764896072 ); hsa04510 Focal adhesion ( 0.0326798218031474 ); hsa04612 Antigen processing and presentation ( 0.03459211752891 ); hsa05210 Colorectal cancer ( 0.0353567340649658 ); hsa04012 ErbB signaling pathway ( 0.0369055805651078 ); hsa05222 Small cell lung cancer ( 0.0369055805651078 ); hsa04210 Apoptosis ( 0.0384802187180184 ); hsa05215 Prostate cancer ( 0.0384802187180184 ); hsa04660 T cell receptor signaling pathway ( 0.0433546313521169 ); hsa04620 Toll-like receptor signaling pathway ( 0.048446052886918 ); ----------------CARTA-------------- g1pathway ( 0.00180067211179996 ); il2pathway ( 0.00200794747832779 ); plcdpathway ( 0.0140022344769239 ); epopathway ( 0.0209306988411465 ); plateletapppathway ( 0.0209306988411465 ); il3pathway ( 0.0448045113362304 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.000410756737969423 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00294917592724416 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0055684399272946 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.00824972897644 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0112276907238288 ); ----------------immu-------------- BCR_signalling_pathway ( 0.0280146634487377 ); TCR_signalling_pathway ( 0.0458739078084871 ); ----------------ARE-------------- ( ); ============================ group2979 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$AP2ALPHA_01 ( 0.00320649121981884 ); ACAGGGT,MIR-10A,MIR-10B ( 0.00597107707261188 ); V$ARP1_01 ( 0.0083985568314454 ); ----------------C4-------------- module_213 ( 0.00243169413534128 ); GNF2_CDH3 ( 0.00311504437227943 ); GNF2_SERPINB5 ( 0.00337835553821687 ); CAR_TNFRSF25 ( 0.00484419593348601 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0016455 RNA polymerase II transcription mediator activity ( ); GO:0010159 specification of organ position ( ); GO:0019064 viral envelope fusion with host membrane ( ); GO:0046814 virion attachment, binding of host cell surface coreceptor ( ); GO:0051825 adhesion to other organism during symbiotic interaction ( ); GO:0051856 adhesion to symbiont ( ); GO:0005915 zonula adherens ( ); GO:0016251 general RNA polymerase II transcription factor activity ( ); ----------------GO-------------- GO:0016455 RNA polymerase II transcription mediator activity ( 0.00137883896198937 ); GO:0010159 specification of organ position ( 0.00346855677876634 ); GO:0019064 viral envelope fusion with host membrane ( 0.00346855677876634 ); GO:0046814 virion attachment, binding of host cell surface coreceptor ( 0.00346855677876634 ); GO:0051825 adhesion to other organism during symbiotic interaction ( 0.00692525643602881 ); GO:0051856 adhesion to symbiont ( 0.00692525643602881 ); GO:0005915 zonula adherens ( 0.00692525643602881 ); GO:0016251 general RNA polymerase II transcription factor activity ( 0.00769020209235751 ); ----------------KEGG-------------- hsa03320 PPAR signaling pathway ( 0.0233138183764475 ); hsa04710 Circadian rhythm ( 0.0441777110054733 ); ----------------CARTA-------------- ( 0.0408488326519187 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2976 ========================= ----------------C2-------------- REACTOME_GENE_EXPRESSION ( 0.003214310131898 ); KEGG_OXIDATIVE_PHOSPHORYLATION ( 0.00684141471870867 ); ----------------C3-------------- ( 0.00717970833799382 ); ----------------C4-------------- module_307 ( 0.00302697701282061 ); module_62 ( 0.00340671529958431 ); module_177 ( 0.00501302763372102 ); module_152 ( 0.00806838156916161 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0006611 protein export from nucleus ( 0.00508597906604967 ); GO:0032991 macromolecular complex ( 0.00508597906604967 ); GO:0005544 calcium-dependent phospholipid binding ( 0.00508597906604967 ); GO:0016082 synaptic vesicle priming ( 0.00508597906604967 ); GO:0033173 calcineurin-NFAT signaling pathway ( 0.00508597906604967 ); GO:0051531 NFAT protein import into nucleus ( 0.00508597906604967 ); GO:0051532 regulation of NFAT protein import into nucleus ( 0.00508597906604967 ); GO:0051533 positive regulation of NFAT protein import into nucleus ( 0.00508597906604967 ); GO:0070075 tear secretion ( 0.00508597906604967 ); GO:0016592 Srb-mediator complex ( 0.00508597906604967 ); GO:0004777 succinate-semialdehyde dehydrogenase activity ( 0.00508597906604967 ); GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity ( 0.00508597906604967 ); GO:0009062 fatty acid catabolic process ( 0.00508597906604967 ); GO:0005737 cytoplasm ( 0.00508597906604967 ); GO:0016054 organic acid catabolic process ( 0.00508597906604967 ); GO:0046395 carboxylic acid catabolic process ( 0.00508597906604967 ); GO:0043229 intracellular organelle ( 0.00508597906604967 ); GO:0043226 organelle ( 0.00508597906604967 ); GO:0006888 ER to Golgi vesicle-mediated transport ( 0.00508597906604967 ); GO:0006461 protein complex assembly ( 0.00508597906604967 ); GO:0070271 protein complex biogenesis ( 0.00508597906604967 ); GO:0006335 DNA replication-dependent nucleosome assembly ( 0.00508597906604967 ); GO:0006429 leucyl-tRNA aminoacylation ( 0.00508597906604967 ); GO:0007023 post-chaperonin tubulin folding pathway ( 0.00508597906604967 ); GO:0009448 gamma-aminobutyric acid metabolic process ( 0.00508597906604967 ); GO:0009450 gamma-aminobutyric acid catabolic process ( 0.00508597906604967 ); GO:0019605 butyrate metabolic process ( 0.00508597906604967 ); GO:0019626 short-chain fatty acid catabolic process ( 0.00508597906604967 ); GO:0034067 protein localization in Golgi apparatus ( 0.00508597906604967 ); GO:0034723 DNA replication-dependent nucleosome organization ( 0.00508597906604967 ); GO:0046359 butyrate catabolic process ( 0.00508597906604967 ); GO:0051281 positive regulation of release of sequestered calcium ion into cytosol ( 0.00508597906604967 ); GO:0004823 leucine-tRNA ligase activity ( 0.00508597906604967 ); GO:0008466 glycogenin glucosyltransferase activity ( 0.00508597906604967 ); GO:0043237 laminin-1 binding ( 0.00508597906604967 ); GO:0044424 intracellular part ( 0.00508597906604967 ); GO:0016874 ligase activity ( 0.00508597906604967 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00508597906604967 ); GO:0043227 membrane-bounded organelle ( 0.00508597906604967 ); ----------------GO-------------- GO:0006611 protein export from nucleus ( 0.00189619434646214 ); GO:0032991 macromolecular complex ( 0.0022552161736985 ); GO:0005544 calcium-dependent phospholipid binding ( 0.00254463794173994 ); GO:0016082 synaptic vesicle priming ( 0.00341828783994325 ); GO:0033173 calcineurin-NFAT signaling pathway ( 0.00341828783994325 ); GO:0051531 NFAT protein import into nucleus ( 0.00341828783994325 ); GO:0051532 regulation of NFAT protein import into nucleus ( 0.00341828783994325 ); GO:0051533 positive regulation of NFAT protein import into nucleus ( 0.00341828783994325 ); GO:0070075 tear secretion ( 0.00341828783994325 ); GO:0016592 Srb-mediator complex ( 0.00341828783994325 ); GO:0004777 succinate-semialdehyde dehydrogenase activity ( 0.00341828783994325 ); GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity ( 0.00341828783994325 ); GO:0009062 fatty acid catabolic process ( 0.00382417665405477 ); GO:0005737 cytoplasm ( 0.00434309792948858 ); GO:0016054 organic acid catabolic process ( 0.00567717999312327 ); GO:0046395 carboxylic acid catabolic process ( 0.00567717999312327 ); GO:0043229 intracellular organelle ( 0.00578958396804458 ); GO:0043226 organelle ( 0.00583194652873886 ); GO:0006888 ER to Golgi vesicle-mediated transport ( 0.00636952273827495 ); GO:0006461 protein complex assembly ( 0.00650849319408937 ); GO:0070271 protein complex biogenesis ( 0.00650849319408937 ); GO:0006335 DNA replication-dependent nucleosome assembly ( 0.00682506224306478 ); GO:0006429 leucyl-tRNA aminoacylation ( 0.00682506224306478 ); GO:0007023 post-chaperonin tubulin folding pathway ( 0.00682506224306478 ); GO:0009448 gamma-aminobutyric acid metabolic process ( 0.00682506224306478 ); GO:0009450 gamma-aminobutyric acid catabolic process ( 0.00682506224306478 ); GO:0019605 butyrate metabolic process ( 0.00682506224306478 ); GO:0019626 short-chain fatty acid catabolic process ( 0.00682506224306478 ); GO:0034067 protein localization in Golgi apparatus ( 0.00682506224306478 ); GO:0034723 DNA replication-dependent nucleosome organization ( 0.00682506224306478 ); GO:0046359 butyrate catabolic process ( 0.00682506224306478 ); GO:0051281 positive regulation of release of sequestered calcium ion into cytosol ( 0.00682506224306478 ); GO:0004823 leucine-tRNA ligase activity ( 0.00682506224306478 ); GO:0008466 glycogenin glucosyltransferase activity ( 0.00682506224306478 ); GO:0043237 laminin-1 binding ( 0.00682506224306478 ); GO:0044424 intracellular part ( 0.00757843750021313 ); GO:0016874 ligase activity ( 0.00802031416381416 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00988007282096869 ); GO:0043227 membrane-bounded organelle ( 0.00994990444777699 ); ----------------KEGG-------------- hsa00190 Oxidative phosphorylation ( 0.00700934302836863 ); hsa05120 Epithelial cell signaling in Helicobacter pylori infection ( 0.022068191980567 ); hsa04612 Antigen processing and presentation ( 0.0328039516852137 ); hsa00290 Valine, leucine and isoleucine biosynthesis ( 0.0369741896203143 ); hsa00920 Sulfur metabolism ( 0.0435505310258183 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.000481765314762195 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0227666573618634 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0293890478393112 ); TIA1_iCLIP_(Wang_2010) ( 0.0332596186601878 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0365104551846371 ); ============================ group2758 ========================= ----------------C2-------------- REACTOME_PROSTANOID_HORMONES ( 0.000567313256798008 ); REACTOME_HORMONE_BIOSYNTHESIS ( 0.000619906662444901 ); BIOCARTA_LAIR_PATHWAY ( 0.00138517828019294 ); KEGG_GRAFT_VERSUS_HOST_DISEASE ( 0.00720621598472584 ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_LCAT ( 0.000682953440871439 ); GNF2_HPN ( 0.000891263763947121 ); GNF2_HPX ( 0.000943009626233345 ); module_58 ( 0.00192298752106802 ); module_130 ( 0.00232812681270813 ); MORF_RBBP8 ( 0.00333802421923487 ); module_214 ( 0.00350053912678825 ); MORF_CDC2L5 ( 0.00850195685647707 ); module_60 ( 0.00996982106087183 ); ----------------C5-------------- MICROBODY ( 0.0099188806568588 ); PEROXISOME ( 0.0099188806568588 ); ----------------GOSLIM-------------- GO:0046456 icosanoid biosynthetic process ( 0.0033393865513417 ); GO:0006690 icosanoid metabolic process ( 0.00519277115199959 ); GO:0002444 myeloid leukocyte mediated immunity ( 0.00721285433771216 ); GO:0044421 extracellular region part ( 0.0033393865513417 ); GO:0005576 extracellular region ( 0.00519277115199959 ); GO:0019370 leukotriene biosynthetic process ( 0.00721285433771216 ); GO:0030510 regulation of BMP signaling pathway ( 0.0033393865513417 ); GO:0043450 alkene biosynthetic process ( 0.00519277115199959 ); GO:0002526 acute inflammatory response ( 0.00721285433771216 ); GO:0006633 fatty acid biosynthetic process ( 0.0033393865513417 ); GO:0006071 glycerol metabolic process ( 0.00519277115199959 ); GO:0006691 leukotriene metabolic process ( 0.00721285433771216 ); GO:0043449 cellular alkene metabolic process ( 0.0033393865513417 ); GO:0050714 positive regulation of protein secretion ( 0.00519277115199959 ); GO:0016561 protein import into peroxisome matrix, translocation ( 0.00721285433771216 ); GO:0046534 positive regulation of photoreceptor cell differentiation ( 0.0033393865513417 ); GO:0005582 collagen type XV ( 0.00519277115199959 ); GO:0008115 sarcosine oxidase activity ( 0.00721285433771216 ); GO:0008116 prostaglandin-I synthase activity ( 0.0033393865513417 ); GO:0008554 sodium-exporting ATPase activity, phosphorylative mechanism ( 0.00519277115199959 ); GO:0015432 bile acid-exporting ATPase activity ( 0.00721285433771216 ); GO:0050031 L-pipecolate oxidase activity ( 0.0033393865513417 ); GO:0016053 organic acid biosynthetic process ( 0.00519277115199959 ); GO:0046394 carboxylic acid biosynthetic process ( 0.00721285433771216 ); GO:0050778 positive regulation of immune response ( 0.0033393865513417 ); GO:0044420 extracellular matrix part ( 0.00519277115199959 ); GO:0006958 complement activation, classical pathway ( 0.00721285433771216 ); GO:0002443 leukocyte mediated immunity ( 0.0033393865513417 ); GO:0002455 humoral immune response mediated by circulating immunoglobulin ( 0.00519277115199959 ); GO:0019751 polyol metabolic process ( 0.00721285433771216 ); GO:0020037 heme binding ( 0.0033393865513417 ); GO:0046906 tetrapyrrole binding ( 0.00519277115199959 ); GO:0044425 membrane part ( 0.00721285433771216 ); GO:0005581 collagen ( 0.0033393865513417 ); GO:0006956 complement activation ( 0.00519277115199959 ); GO:0007155 cell adhesion ( 0.00721285433771216 ); GO:0022610 biological adhesion ( 0.0033393865513417 ); GO:0045177 apical part of cell ( 0.00519277115199959 ); GO:0030216 keratinocyte differentiation ( 0.00721285433771216 ); GO:0001660 fever ( 0.0033393865513417 ); GO:0001794 type IIa hypersensitivity ( 0.00519277115199959 ); GO:0001796 regulation of type IIa hypersensitivity ( 0.00721285433771216 ); GO:0001798 positive regulation of type IIa hypersensitivity ( 0.0033393865513417 ); GO:0002445 type II hypersensitivity ( 0.00519277115199959 ); GO:0002888 positive regulation of myeloid leukocyte mediated immunity ( 0.00721285433771216 ); GO:0002892 regulation of type II hypersensitivity ( 0.0033393865513417 ); GO:0002894 positive regulation of type II hypersensitivity ( 0.00519277115199959 ); GO:0030859 polarized epithelial cell differentiation ( 0.00721285433771216 ); GO:0045198 establishment of epithelial cell apical/basal polarity ( 0.0033393865513417 ); GO:0046532 regulation of photoreceptor cell differentiation ( 0.00519277115199959 ); GO:0008539 proteasome inhibitor activity ( 0.00721285433771216 ); GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor ( 0.0033393865513417 ); GO:0032879 regulation of localization ( 0.00519277115199959 ); GO:0051050 positive regulation of transport ( 0.00721285433771216 ); GO:0002541 activation of plasma proteins during acute inflammatory response ( 0.0033393865513417 ); GO:0050708 regulation of protein secretion ( 0.00519277115199959 ); GO:0032787 monocarboxylic acid metabolic process ( 0.00721285433771216 ); GO:0048584 positive regulation of response to stimulus ( 0.0033393865513417 ); GO:0051222 positive regulation of protein transport ( 0.00519277115199959 ); GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus ( 0.00721285433771216 ); GO:0002885 positive regulation of hypersensitivity ( 0.0033393865513417 ); GO:0044240 multicellular organismal lipid catabolic process ( 0.00519277115199959 ); GO:0046653 tetrahydrofolate metabolic process ( 0.00721285433771216 ); GO:0032449 CBM complex ( 0.0033393865513417 ); ----------------GO-------------- GO:0046456 icosanoid biosynthetic process ( 9.20790932530082e-05 ); GO:0006690 icosanoid metabolic process ( 0.000238959995789507 ); GO:0002444 myeloid leukocyte mediated immunity ( 0.000932725716290044 ); GO:0044421 extracellular region part ( 0.000995464901945304 ); GO:0005576 extracellular region ( 0.00145654086377085 ); GO:0019370 leukotriene biosynthetic process ( 0.00173433663504448 ); GO:0030510 regulation of BMP signaling pathway ( 0.00173433663504448 ); GO:0043450 alkene biosynthetic process ( 0.00173433663504448 ); GO:0002526 acute inflammatory response ( 0.0021268818548271 ); GO:0006633 fatty acid biosynthetic process ( 0.0021268818548271 ); GO:0006071 glycerol metabolic process ( 0.00232812681270813 ); GO:0006691 leukotriene metabolic process ( 0.00232812681270813 ); GO:0043449 cellular alkene metabolic process ( 0.00254449372608592 ); GO:0050714 positive regulation of protein secretion ( 0.00300452051011932 ); GO:0016561 protein import into peroxisome matrix, translocation ( 0.00326748102347518 ); GO:0046534 positive regulation of photoreceptor cell differentiation ( 0.00326748102347518 ); GO:0005582 collagen type XV ( 0.00326748102347518 ); GO:0008115 sarcosine oxidase activity ( 0.00326748102347518 ); GO:0008116 prostaglandin-I synthase activity ( 0.00326748102347518 ); GO:0008554 sodium-exporting ATPase activity, phosphorylative mechanism ( 0.00326748102347518 ); GO:0015432 bile acid-exporting ATPase activity ( 0.00326748102347518 ); GO:0050031 L-pipecolate oxidase activity ( 0.00326748102347518 ); GO:0016053 organic acid biosynthetic process ( 0.003295587391527 ); GO:0046394 carboxylic acid biosynthetic process ( 0.003295587391527 ); GO:0050778 positive regulation of immune response ( 0.00361111133264246 ); GO:0044420 extracellular matrix part ( 0.00372024339173815 ); GO:0006958 complement activation, classical pathway ( 0.00376189689322374 ); GO:0002443 leukocyte mediated immunity ( 0.00383137326596227 ); GO:0002455 humoral immune response mediated by circulating immunoglobulin ( 0.00489494662380838 ); GO:0019751 polyol metabolic process ( 0.00551322882411296 ); GO:0020037 heme binding ( 0.00560293801150567 ); GO:0046906 tetrapyrrole binding ( 0.00560293801150567 ); GO:0044425 membrane part ( 0.0057721173685569 ); GO:0005581 collagen ( 0.00583510772479384 ); GO:0006956 complement activation ( 0.00616540244875193 ); GO:0007155 cell adhesion ( 0.00640350349494706 ); GO:0022610 biological adhesion ( 0.00640350349494706 ); GO:0045177 apical part of cell ( 0.00648957274961511 ); GO:0030216 keratinocyte differentiation ( 0.00650405630320692 ); GO:0001660 fever ( 0.00652444933905316 ); GO:0001794 type IIa hypersensitivity ( 0.00652444933905316 ); GO:0001796 regulation of type IIa hypersensitivity ( 0.00652444933905316 ); GO:0001798 positive regulation of type IIa hypersensitivity ( 0.00652444933905316 ); GO:0002445 type II hypersensitivity ( 0.00652444933905316 ); GO:0002888 positive regulation of myeloid leukocyte mediated immunity ( 0.00652444933905316 ); GO:0002892 regulation of type II hypersensitivity ( 0.00652444933905316 ); GO:0002894 positive regulation of type II hypersensitivity ( 0.00652444933905316 ); GO:0030859 polarized epithelial cell differentiation ( 0.00652444933905316 ); GO:0045198 establishment of epithelial cell apical/basal polarity ( 0.00652444933905316 ); GO:0046532 regulation of photoreceptor cell differentiation ( 0.00652444933905316 ); GO:0008539 proteasome inhibitor activity ( 0.00652444933905316 ); GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor ( 0.00652444933905316 ); GO:0032879 regulation of localization ( 0.0065666517984193 ); GO:0051050 positive regulation of transport ( 0.00664499507810193 ); GO:0002541 activation of plasma proteins during acute inflammatory response ( 0.00685101286605026 ); GO:0050708 regulation of protein secretion ( 0.00685101286605026 ); GO:0032787 monocarboxylic acid metabolic process ( 0.0084499687675716 ); GO:0048584 positive regulation of response to stimulus ( 0.00943688106615378 ); GO:0051222 positive regulation of protein transport ( 0.00950750150961826 ); GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus ( 0.00977093824322917 ); GO:0002885 positive regulation of hypersensitivity ( 0.00977093824322917 ); GO:0044240 multicellular organismal lipid catabolic process ( 0.00977093824322917 ); GO:0046653 tetrahydrofolate metabolic process ( 0.00977093824322917 ); GO:0032449 CBM complex ( 0.00977093824322917 ); ----------------KEGG-------------- hsa05332 Graft-versus-host disease ( 0.00720621598472584 ); hsa00590 Arachidonic acid metabolism ( 0.0134864777055175 ); hsa04610 Complement and coagulation cascades ( 0.0208513855681577 ); hsa00791 Atrazine degradation ( 0.0290316555950969 ); hsa04512 ECM-receptor interaction ( 0.0301930680028318 ); hsa05222 Small cell lung cancer ( 0.0322278560523948 ); hsa05060 Prion disease ( 0.0416667110851552 ); ----------------CARTA-------------- ceramidepathway ( 0.000290648338335635 ); cacampathway ( 0.00652444933905316 ); mbdpathway ( 0.00652444933905316 ); metpathway ( 0.00910398330465386 ); tercpathway ( 0.00977093824322917 ); egfpathway ( 0.00977093824322917 ); fcer1pathway ( 0.0111996446902602 ); relapathway ( 0.0162326104847262 ); il3pathway ( 0.0416667110851552 ); hespathway ( 0.0416667110851552 ); melanocytepathway ( 0.0416667110851552 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2994 ========================= ----------------C2-------------- REACTOME_CELL_CELL_ADHESION_SYSTEMS ( 0.000827634364442199 ); REACTOME_CELL_JUNCTION_ORGANIZATION ( 0.00221830703882004 ); REACTOME_TIGHT_JUNCTION_INTERACTIONS ( 0.00393029304218469 ); KEGG_TIGHT_JUNCTION ( 0.00812079542299248 ); ----------------C3-------------- ( 0.000570727568407036 ); ----------------C4-------------- MORF_LTK ( 0.00778859629151206 ); module_195 ( 0.00863459208966724 ); module_356 ( 0.00916711898897208 ); ----------------C5-------------- TRANSCRIPTION_REPRESSOR_ACTIVITY ( 9.48951513462193e-05 ); EARLY_ENDOSOME ( 0.00141601918871158 ); MESODERM_DEVELOPMENT ( 0.00212083054772676 ); TRANSCRIPTION_COREPRESSOR_ACTIVITY ( 0.00297230577574984 ); TRANSCRIPTION__DNA_DEPENDENT ( 0.00313144743740161 ); RNA_BIOSYNTHETIC_PROCESS ( 0.00318749254238922 ); NEGATIVE_REGULATION_OF_NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 0.00383188610414541 ); SKELETAL_DEVELOPMENT ( 0.00397532886026958 ); COENZYME_METABOLIC_PROCESS ( 0.00593377939360951 ); CELL_MATRIX_ADHESION ( 0.00593377939360951 ); CELL_SUBSTRATE_ADHESION ( 0.00625093379696639 ); NEGATIVE_REGULATION_OF_TRANSCRIPTION__DNA_DEPENDENT ( 0.00730567884223029 ); NEGATIVE_REGULATION_OF_RNA_METABOLIC_PROCESS ( 0.00730567884223029 ); TRANSCRIPTION ( 0.00776007318956238 ); NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.00789579413940076 ); NEGATIVE_REGULATION_OF_METABOLIC_PROCESS ( 0.00811361358046007 ); ----------------GOSLIM-------------- GO:0007498 mesoderm development ( ); GO:0048332 mesoderm morphogenesis ( ); GO:0007423 sensory organ development ( ); GO:0001654 eye development ( ); GO:0008301 DNA bending activity ( ); GO:0016564 transcription repressor activity ( ); GO:0000146 microfilament motor activity ( ); GO:0043010 camera-type eye development ( ); GO:0048010 vascular endothelial growth factor receptor signaling pathway ( ); GO:0001501 skeletal system development ( ); GO:0001657 ureteric bud development ( ); GO:0030048 actin filament-based movement ( ); GO:0042475 odontogenesis of dentine-containing tooth ( ); GO:0014009 glial cell proliferation ( ); GO:0014010 Schwann cell proliferation ( ); GO:0021512 spinal cord anterior/posterior patterning ( ); GO:0032808 lacrimal gland development ( ); GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein ( ); GO:0005749 mitochondrial respiratory chain complex II ( ); GO:0045257 succinate dehydrogenase complex (ubiquinone) ( ); GO:0045281 succinate dehydrogenase complex ( ); GO:0045283 fumarate reductase complex ( ); GO:0008265 Mo-molybdopterin cofactor sulfurase activity ( ); GO:0001707 mesoderm formation ( ); GO:0048598 embryonic morphogenesis ( ); GO:0009888 tissue development ( ); GO:0001656 metanephros development ( ); GO:0001704 formation of primary germ layer ( ); GO:0048729 tissue morphogenesis ( ); GO:0009790 embryonic development ( ); GO:0042476 odontogenesis ( ); GO:0009887 organ morphogenesis ( ); GO:0003714 transcription corepressor activity ( ); GO:0046545 development of primary female sexual characteristics ( ); GO:0046660 female sex differentiation ( ); GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( ); GO:0001957 intramembranous ossification ( ); GO:0001958 endochondral ossification ( ); GO:0002063 chondrocyte development ( ); GO:0006423 cysteinyl-tRNA aminoacylation ( ); GO:0032275 luteinizing hormone secretion ( ); GO:0032703 negative regulation of interleukin-2 production ( ); GO:0060349 bone morphogenesis ( ); GO:0060350 endochondral bone morphogenesis ( ); GO:0045273 respiratory chain complex II ( ); GO:0004421 hydroxymethylglutaryl-CoA synthase activity ( ); GO:0004756 selenide, water dikinase activity ( ); GO:0004817 cysteine-tRNA ligase activity ( ); GO:0008177 succinate dehydrogenase (ubiquinone) activity ( ); GO:0008327 methyl-CpG binding ( ); GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor ( ); GO:0016781 phosphotransferase activity, paired acceptors ( ); GO:0030705 cytoskeleton-dependent intracellular transport ( ); GO:0010558 negative regulation of macromolecule biosynthetic process ( ); GO:0031327 negative regulation of cellular biosynthetic process ( ); GO:0042127 regulation of cell proliferation ( ); GO:0009890 negative regulation of biosynthetic process ( ); GO:0048731 system development ( ); GO:0030540 female genitalia development ( ); GO:0032233 positive regulation of actin filament bundle formation ( ); GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein ( ); GO:0051496 positive regulation of stress fiber formation ( ); GO:0031082 BLOC complex ( ); GO:0031083 BLOC-1 complex ( ); GO:0000104 succinate dehydrogenase activity ( ); GO:0008285 negative regulation of cell proliferation ( ); ----------------GO-------------- GO:0007498 mesoderm development ( 2.78222867672829e-05 ); GO:0048332 mesoderm morphogenesis ( 9.94240410093521e-05 ); GO:0007423 sensory organ development ( 0.000104379204872343 ); GO:0001654 eye development ( 0.000186624249024601 ); GO:0008301 DNA bending activity ( 0.000423220539657563 ); GO:0016564 transcription repressor activity ( 0.000720015722659234 ); GO:0000146 microfilament motor activity ( 0.000848996396561887 ); GO:0043010 camera-type eye development ( 0.00119819902706271 ); GO:0048010 vascular endothelial growth factor receptor signaling pathway ( 0.00126121178192291 ); GO:0001501 skeletal system development ( 0.00143107790280235 ); GO:0001657 ureteric bud development ( 0.00212083054772676 ); GO:0030048 actin filament-based movement ( 0.00212083054772676 ); GO:0042475 odontogenesis of dentine-containing tooth ( 0.00296003380694377 ); GO:0014009 glial cell proliferation ( 0.00311667420700745 ); GO:0014010 Schwann cell proliferation ( 0.00311667420700745 ); GO:0021512 spinal cord anterior/posterior patterning ( 0.00311667420700745 ); GO:0032808 lacrimal gland development ( 0.00311667420700745 ); GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein ( 0.00311667420700745 ); GO:0005749 mitochondrial respiratory chain complex II ( 0.00311667420700745 ); GO:0045257 succinate dehydrogenase complex (ubiquinone) ( 0.00311667420700745 ); GO:0045281 succinate dehydrogenase complex ( 0.00311667420700745 ); GO:0045283 fumarate reductase complex ( 0.00311667420700745 ); GO:0008265 Mo-molybdopterin cofactor sulfurase activity ( 0.00311667420700745 ); GO:0001707 mesoderm formation ( 0.00319044110642683 ); GO:0048598 embryonic morphogenesis ( 0.00326474080514426 ); GO:0009888 tissue development ( 0.00359405260579355 ); GO:0001656 metanephros development ( 0.00367562191194207 ); GO:0001704 formation of primary germ layer ( 0.00393029304218469 ); GO:0048729 tissue morphogenesis ( 0.00478622593079778 ); GO:0009790 embryonic development ( 0.00495478006514089 ); GO:0042476 odontogenesis ( 0.00502833212625243 ); GO:0009887 organ morphogenesis ( 0.00527732897328832 ); GO:0003714 transcription corepressor activity ( 0.00582719265870846 ); GO:0046545 development of primary female sexual characteristics ( 0.00593377939360951 ); GO:0046660 female sex differentiation ( 0.00593377939360951 ); GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00608914807129315 ); GO:0001957 intramembranous ossification ( 0.00622379094736358 ); GO:0001958 endochondral ossification ( 0.00622379094736358 ); GO:0002063 chondrocyte development ( 0.00622379094736358 ); GO:0006423 cysteinyl-tRNA aminoacylation ( 0.00622379094736358 ); GO:0032275 luteinizing hormone secretion ( 0.00622379094736358 ); GO:0032703 negative regulation of interleukin-2 production ( 0.00622379094736358 ); GO:0060349 bone morphogenesis ( 0.00622379094736358 ); GO:0060350 endochondral bone morphogenesis ( 0.00622379094736358 ); GO:0045273 respiratory chain complex II ( 0.00622379094736358 ); GO:0004421 hydroxymethylglutaryl-CoA synthase activity ( 0.00622379094736358 ); GO:0004756 selenide, water dikinase activity ( 0.00622379094736358 ); GO:0004817 cysteine-tRNA ligase activity ( 0.00622379094736358 ); GO:0008177 succinate dehydrogenase (ubiquinone) activity ( 0.00622379094736358 ); GO:0008327 methyl-CpG binding ( 0.00622379094736358 ); GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor ( 0.00622379094736358 ); GO:0016781 phosphotransferase activity, paired acceptors ( 0.00622379094736358 ); GO:0030705 cytoskeleton-dependent intracellular transport ( 0.00684107128231018 ); GO:0010558 negative regulation of macromolecule biosynthetic process ( 0.00724171832690003 ); GO:0031327 negative regulation of cellular biosynthetic process ( 0.0080351714856062 ); GO:0042127 regulation of cell proliferation ( 0.00818373949982463 ); GO:0009890 negative regulation of biosynthetic process ( 0.00836889460972696 ); GO:0048731 system development ( 0.00898431143394926 ); GO:0030540 female genitalia development ( 0.00932137905058905 ); GO:0032233 positive regulation of actin filament bundle formation ( 0.00932137905058905 ); GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein ( 0.00932137905058905 ); GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein ( 0.00932137905058905 ); GO:0051496 positive regulation of stress fiber formation ( 0.00932137905058905 ); GO:0031082 BLOC complex ( 0.00932137905058905 ); GO:0031083 BLOC-1 complex ( 0.00932137905058905 ); GO:0000104 succinate dehydrogenase activity ( 0.00932137905058905 ); GO:0008285 negative regulation of cell proliferation ( 0.00999971536429806 ); ----------------KEGG-------------- hsa04530 Tight junction ( 0.00812079542299248 ); hsa05218 Melanoma ( 0.0206915856049315 ); hsa00072 Synthesis and degradation of ketone bodies ( 0.0277084099995377 ); hsa04810 Regulation of actin cytoskeleton ( 0.0278146326300746 ); hsa00272 Cysteine metabolism ( 0.0397794667100284 ); hsa04010 MAPK signaling pathway ( 0.0497681059285933 ); ----------------CARTA-------------- ( 0.0487358812875214 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0476213803615418 ); ----------------ARE-------------- ( ); ============================ group2740 ========================= ----------------C2-------------- REACTOME_HEMOSTASIS ( 0.000104290366401329 ); REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS ( 0.000770087911722535 ); REACTOME_FORMATION_OF_PLATELET_PLUG ( 0.00170580760050307 ); REACTOME_INTEGRIN_ALPHAIIBBETA3_SIGNALING ( 0.0018294195599898 ); REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION ( 0.00233759469179194 ); ----------------C3-------------- TGTTTGY_V$HNF3_Q6 ( 0.000822890680090026 ); STTTCRNTTT_V$IRF_Q6 ( 0.00783376172025377 ); ----------------C4-------------- module_41 ( 0.00346078719064488 ); GNF2_CYP2B6 ( 0.00812175862536618 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0033292 T-tubule organization ( ); GO:0060299 negative regulation of sarcomere organization ( ); GO:0060306 regulation of membrane repolarization ( ); GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization ( ); GO:0004782 sulfinoalanine decarboxylase activity ( ); GO:0050528 acyloxyacyl hydrolase activity ( ); GO:0030141 secretory granule ( ); GO:0007308 oocyte construction ( ); GO:0007309 oocyte axis specification ( ); GO:0009256 10-formyltetrahydrofolate metabolic process ( ); GO:0009258 10-formyltetrahydrofolate catabolic process ( ); GO:0009397 folic acid and derivative catabolic process ( ); GO:0014819 regulation of skeletal muscle contraction ( ); GO:0004466 long-chain-acyl-CoA dehydrogenase activity ( ); GO:0031091 platelet alpha granule ( ); GO:0010614 negative regulation of cardiac muscle hypertrophy ( ); GO:0010616 negative regulation of cardiac muscle adaptation ( ); GO:0014741 negative regulation of muscle hypertrophy ( ); GO:0048601 oocyte morphogenesis ( ); GO:0051001 negative regulation of nitric-oxide synthase activity ( ); GO:0060297 regulation of sarcomere organization ( ); GO:0004465 lipoprotein lipase activity ( ); GO:0016155 formyltetrahydrofolate dehydrogenase activity ( ); GO:0031177 phosphopantetheine binding ( ); ----------------GO-------------- GO:0033292 T-tubule organization ( 0.00276479163524901 ); GO:0060299 negative regulation of sarcomere organization ( 0.00276479163524901 ); GO:0060306 regulation of membrane repolarization ( 0.00276479163524901 ); GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization ( 0.00276479163524901 ); GO:0004782 sulfinoalanine decarboxylase activity ( 0.00276479163524901 ); GO:0050528 acyloxyacyl hydrolase activity ( 0.00276479163524901 ); GO:0030141 secretory granule ( 0.00377729641809753 ); GO:0007308 oocyte construction ( 0.00552207780356095 ); GO:0007309 oocyte axis specification ( 0.00552207780356095 ); GO:0009256 10-formyltetrahydrofolate metabolic process ( 0.00552207780356095 ); GO:0009258 10-formyltetrahydrofolate catabolic process ( 0.00552207780356095 ); GO:0009397 folic acid and derivative catabolic process ( 0.00552207780356095 ); GO:0014819 regulation of skeletal muscle contraction ( 0.00552207780356095 ); GO:0004466 long-chain-acyl-CoA dehydrogenase activity ( 0.00552207780356095 ); GO:0031091 platelet alpha granule ( 0.00688558372999438 ); GO:0010614 negative regulation of cardiac muscle hypertrophy ( 0.00827187850341526 ); GO:0010616 negative regulation of cardiac muscle adaptation ( 0.00827187850341526 ); GO:0014741 negative regulation of muscle hypertrophy ( 0.00827187850341526 ); GO:0048601 oocyte morphogenesis ( 0.00827187850341526 ); GO:0051001 negative regulation of nitric-oxide synthase activity ( 0.00827187850341526 ); GO:0060297 regulation of sarcomere organization ( 0.00827187850341526 ); GO:0004465 lipoprotein lipase activity ( 0.00827187850341526 ); GO:0016155 formyltetrahydrofolate dehydrogenase activity ( 0.00827187850341526 ); GO:0031177 phosphopantetheine binding ( 0.00827187850341526 ); ----------------KEGG-------------- hsa04510 Focal adhesion ( 0.0174407781957247 ); hsa00430 Taurine and hypotaurine metabolism ( 0.0273125592119863 ); ----------------CARTA-------------- ( 0.0353625471913852 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2953 ========================= ----------------C2-------------- KEGG_RIBOFLAVIN_METABOLISM ( 0.00061490561110911 ); KEGG_O_GLYCAN_BIOSYNTHESIS ( 0.00218358787711866 ); ----------------C3-------------- TCCCCAC,MIR-491 ( 0.00644473738276132 ); V$NFY_C ( 0.00794132396588367 ); AGTCTTA,MIR-499 ( 0.00850253612463227 ); ----------------C4-------------- GCM_TEC ( 0.00248248510589313 ); module_257 ( 0.00390694945449086 ); GCM_SUPT4H1 ( 0.00796377736615434 ); ----------------C5-------------- MACROMOLECULAR_COMPLEX_DISASSEMBLY ( 0.00053883550943189 ); HYDROLASE_ACTIVITY__ACTING_ON_CARBON_NITROGEN__BUT_NOT_PEPTIDE__BONDS__IN_LINEAR_AMIDES ( 0.00087237817746628 ); REGULATION_OF_TRANSLATIONAL_INITIATION ( 0.00233075219192604 ); CELLULAR_COMPONENT_DISASSEMBLY ( 0.00263876563783974 ); REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION_AND_BIOGENESIS ( 0.00281868515788469 ); TRANSLATIONAL_INITIATION ( 0.00367078252296444 ); REGULATION_OF_GENE_EXPRESSION ( 0.00391838074524131 ); HYDROLASE_ACTIVITY__ACTING_ON_CARBON_NITROGEN__BUT_NOT_PEPTIDE__BONDS ( 0.00465206227832047 ); PROTEIN_METABOLIC_PROCESS ( 0.00552921272150708 ); REGULATION_OF_PROTEIN_METABOLIC_PROCESS ( 0.00711026476467287 ); PROTEIN_IMPORT ( 0.00823115346765459 ); REGULATION_OF_METABOLIC_PROCESS ( 0.0085644025186747 ); PROTEIN_RNA_COMPLEX_ASSEMBLY ( 0.00962775079881166 ); ----------------GOSLIM-------------- GO:0016568 chromatin modification ( 0.00811092678086246 ); GO:0006917 induction of apoptosis ( 0.00811092678086246 ); GO:0012502 induction of programmed cell death ( 0.00811092678086246 ); GO:0016043 cellular component organization ( 0.00811092678086246 ); GO:0008611 ether lipid biosynthetic process ( 0.00811092678086246 ); GO:0019244 lactate biosynthetic process from pyruvate ( 0.00811092678086246 ); GO:0019249 lactate biosynthetic process ( 0.00811092678086246 ); GO:0032790 ribosome disassembly ( 0.00811092678086246 ); GO:0032968 positive regulation of RNA elongation from RNA polymerase II promoter ( 0.00811092678086246 ); GO:0032988 ribonucleoprotein complex disassembly ( 0.00811092678086246 ); GO:0034243 regulation of RNA elongation from RNA polymerase II promoter ( 0.00811092678086246 ); GO:0046485 ether lipid metabolic process ( 0.00811092678086246 ); GO:0005053 peroxisome matrix targeting signal-2 binding ( 0.00811092678086246 ); GO:0050809 diazepam binding ( 0.00811092678086246 ); GO:0017038 protein import ( 0.00811092678086246 ); GO:0043065 positive regulation of apoptosis ( 0.00811092678086246 ); GO:0043068 positive regulation of programmed cell death ( 0.00811092678086246 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00811092678086246 ); GO:0006446 regulation of translational initiation ( 0.00811092678086246 ); GO:0030145 manganese ion binding ( 0.00811092678086246 ); GO:0002378 immunoglobulin biosynthetic process ( 0.00811092678086246 ); GO:0006089 lactate metabolic process ( 0.00811092678086246 ); GO:0006478 peptidyl-tyrosine sulfation ( 0.00811092678086246 ); GO:0021990 neural plate formation ( 0.00811092678086246 ); GO:0032784 regulation of RNA elongation ( 0.00811092678086246 ); GO:0032786 positive regulation of RNA elongation ( 0.00811092678086246 ); GO:0000268 peroxisome targeting sequence binding ( 0.00811092678086246 ); GO:0008148 negative transcription elongation factor activity ( 0.00811092678086246 ); GO:0008476 protein-tyrosine sulfotransferase activity ( 0.00811092678086246 ); GO:0019807 aspartoacylase activity ( 0.00811092678086246 ); GO:0042903 tubulin deacetylase activity ( 0.00811092678086246 ); GO:0043024 ribosomal small subunit binding ( 0.00811092678086246 ); GO:0010608 posttranscriptional regulation of gene expression ( 0.00811092678086246 ); GO:0010605 negative regulation of macromolecule metabolic process ( 0.00811092678086246 ); GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ( 0.00811092678086246 ); GO:0007029 endoplasmic reticulum organization ( 0.00811092678086246 ); GO:0018242 protein amino acid O-linked glycosylation via serine ( 0.00811092678086246 ); GO:0018243 protein amino acid O-linked glycosylation via threonine ( 0.00811092678086246 ); GO:0019805 quinolinate biosynthetic process ( 0.00811092678086246 ); GO:0021988 olfactory lobe development ( 0.00811092678086246 ); GO:0043090 amino acid import ( 0.00811092678086246 ); GO:0043092 L-amino acid import ( 0.00811092678086246 ); GO:0051938 L-glutamate import ( 0.00811092678086246 ); GO:0004406 H3/H4 histone acetyltransferase activity ( 0.00811092678086246 ); GO:0009892 negative regulation of metabolic process ( 0.00811092678086246 ); GO:0006865 amino acid transport ( 0.00811092678086246 ); GO:0006531 aspartate metabolic process ( 0.00811092678086246 ); GO:0006533 aspartate catabolic process ( 0.00811092678086246 ); GO:0031053 primary microRNA processing ( 0.00811092678086246 ); GO:0047496 vesicle transport along microtubule ( 0.00811092678086246 ); GO:0000900 translation repressor activity, nucleic acid binding ( 0.00811092678086246 ); GO:0030676 Rac guanyl-nucleotide exchange factor activity ( 0.00811092678086246 ); GO:0034623 cellular macromolecular complex disassembly ( 0.00811092678086246 ); GO:0051276 chromosome organization ( 0.00811092678086246 ); GO:0006413 translational initiation ( 0.00811092678086246 ); ----------------GO-------------- GO:0016568 chromatin modification ( 0.000980611755191668 ); GO:0006917 induction of apoptosis ( 0.00141647595762067 ); GO:0012502 induction of programmed cell death ( 0.0014412933487339 ); GO:0016043 cellular component organization ( 0.00150154033896772 ); GO:0008611 ether lipid biosynthetic process ( 0.00231237118584426 ); GO:0019244 lactate biosynthetic process from pyruvate ( 0.00231237118584426 ); GO:0019249 lactate biosynthetic process ( 0.00231237118584426 ); GO:0032790 ribosome disassembly ( 0.00231237118584426 ); GO:0032968 positive regulation of RNA elongation from RNA polymerase II promoter ( 0.00231237118584426 ); GO:0032988 ribonucleoprotein complex disassembly ( 0.00231237118584426 ); GO:0034243 regulation of RNA elongation from RNA polymerase II promoter ( 0.00231237118584426 ); GO:0046485 ether lipid metabolic process ( 0.00231237118584426 ); GO:0005053 peroxisome matrix targeting signal-2 binding ( 0.00231237118584426 ); GO:0050809 diazepam binding ( 0.00231237118584426 ); GO:0017038 protein import ( 0.0029512725290116 ); GO:0043065 positive regulation of apoptosis ( 0.00341602439035277 ); GO:0043068 positive regulation of programmed cell death ( 0.00355395648403318 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.003695641280346 ); GO:0006446 regulation of translational initiation ( 0.00405022905946484 ); GO:0030145 manganese ion binding ( 0.00440454627220106 ); GO:0002378 immunoglobulin biosynthetic process ( 0.00461951128867211 ); GO:0006089 lactate metabolic process ( 0.00461951128867211 ); GO:0006478 peptidyl-tyrosine sulfation ( 0.00461951128867211 ); GO:0021990 neural plate formation ( 0.00461951128867211 ); GO:0032784 regulation of RNA elongation ( 0.00461951128867211 ); GO:0032786 positive regulation of RNA elongation ( 0.00461951128867211 ); GO:0000268 peroxisome targeting sequence binding ( 0.00461951128867211 ); GO:0008148 negative transcription elongation factor activity ( 0.00461951128867211 ); GO:0008476 protein-tyrosine sulfotransferase activity ( 0.00461951128867211 ); GO:0019807 aspartoacylase activity ( 0.00461951128867211 ); GO:0042903 tubulin deacetylase activity ( 0.00461951128867211 ); GO:0043024 ribosomal small subunit binding ( 0.00461951128867211 ); GO:0010608 posttranscriptional regulation of gene expression ( 0.00571020655916227 ); GO:0010605 negative regulation of macromolecule metabolic process ( 0.00591480355004861 ); GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ( 0.00644473738276132 ); GO:0007029 endoplasmic reticulum organization ( 0.00692143187993066 ); GO:0018242 protein amino acid O-linked glycosylation via serine ( 0.00692143187993066 ); GO:0018243 protein amino acid O-linked glycosylation via threonine ( 0.00692143187993066 ); GO:0019805 quinolinate biosynthetic process ( 0.00692143187993066 ); GO:0021988 olfactory lobe development ( 0.00692143187993066 ); GO:0043090 amino acid import ( 0.00692143187993066 ); GO:0043092 L-amino acid import ( 0.00692143187993066 ); GO:0051938 L-glutamate import ( 0.00692143187993066 ); GO:0004406 H3/H4 histone acetyltransferase activity ( 0.00692143187993066 ); GO:0009892 negative regulation of metabolic process ( 0.00763223535798961 ); GO:0006865 amino acid transport ( 0.00905724467622987 ); GO:0006531 aspartate metabolic process ( 0.00921814450605041 ); GO:0006533 aspartate catabolic process ( 0.00921814450605041 ); GO:0031053 primary microRNA processing ( 0.00921814450605041 ); GO:0047496 vesicle transport along microtubule ( 0.00921814450605041 ); GO:0000900 translation repressor activity, nucleic acid binding ( 0.00921814450605041 ); GO:0030676 Rac guanyl-nucleotide exchange factor activity ( 0.00921814450605041 ); GO:0034623 cellular macromolecular complex disassembly ( 0.0093405325154067 ); GO:0051276 chromosome organization ( 0.00937473677751325 ); GO:0006413 translational initiation ( 0.00962775079881166 ); ----------------KEGG-------------- hsa00740 Riboflavin metabolism ( 0.00053883550943189 ); hsa00512 O-Glycan biosynthesis ( 0.00233075219192604 ); hsa00730 Thiamine metabolism ( 0.016077149683752 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0304736237607091 ); hsa00361 gamma-Hexachlorocyclohexane degradation ( 0.0408316918454881 ); ----------------CARTA-------------- wnvpathway ( 0.00692143187993066 ); npp1pathway ( 0.016077149683752 ); telpathway ( 0.0296560925557611 ); ----------------RBP-------------- ( 0.0205161946310071 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2761 ========================= ----------------C2-------------- REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE ( 0.00549987478012663 ); KEGG_RETINOL_METABOLISM ( 0.00713039339792743 ); ----------------C3-------------- V$AP1_Q4_01 ( 0.001130692745465 ); ARGGGTTAA_UNKNOWN ( 0.00133429565835702 ); V$CREB_Q4_01 ( 0.00546383646733655 ); V$FOXD3_01 ( 0.00575594775536506 ); V$SMAD3_Q6 ( 0.00724238715110439 ); V$SP1_01 ( 0.00782337878297193 ); V$LFA1_Q6 ( 0.00843123595776283 ); V$AP4_01 ( 0.00880896123093076 ); ----------------C4-------------- GNF2_TST ( 0.00158835577752988 ); GNF2_GSTM1 ( 0.00182174357273608 ); GNF2_LCAT ( 0.00264660011458114 ); GNF2_HPN ( 0.00323611349566708 ); GNF2_HPX ( 0.00337716131130956 ); GNF2_CEBPA ( 0.00922814275233519 ); ----------------C5-------------- LIPID_METABOLIC_PROCESS ( 0.000691191556603798 ); RHO_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00316877901294798 ); PROTEIN_BINDING__BRIDGING ( 0.00788821455486079 ); RAS_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00950750150961825 ); ----------------GOSLIM-------------- GO:0005789 endoplasmic reticulum membrane ( ); GO:0044432 endoplasmic reticulum part ( ); GO:0042175 nuclear envelope-endoplasmic reticulum network ( ); GO:0002315 marginal zone B cell differentiation ( ); GO:0006369 termination of RNA polymerase II transcription ( ); GO:0045415 negative regulation of interleukin-8 biosynthetic process ( ); GO:0032996 Bcl3-Bcl10 complex ( ); GO:0034366 spherical high-density lipoprotein particle ( ); GO:0002266 follicular dendritic cell activation ( ); GO:0002268 follicular dendritic cell differentiation ( ); GO:0016264 gap junction assembly ( ); GO:0042091 interleukin-10 biosynthetic process ( ); GO:0042832 defense response to protozoan ( ); GO:0045074 regulation of interleukin-10 biosynthetic process ( ); GO:0045082 positive regulation of interleukin-10 biosynthetic process ( ); GO:0033257 Bcl3/NF-kappaB2 complex ( ); GO:0004605 phosphatidate cytidylyltransferase activity ( ); GO:0008393 fatty acid (omega-1)-hydroxylase activity ( ); GO:0018685 alkane 1-monooxygenase activity ( ); GO:0006898 receptor-mediated endocytosis ( ); GO:0001562 response to protozoan ( ); GO:0019730 antimicrobial humoral response ( ); GO:0031648 protein destabilization ( ); GO:0034653 retinoic acid catabolic process ( ); GO:0042363 fat-soluble vitamin catabolic process ( ); GO:0042536 negative regulation of tumor necrosis factor biosynthetic process ( ); GO:0045717 negative regulation of fatty acid biosynthetic process ( ); GO:0045922 negative regulation of fatty acid metabolic process ( ); GO:0004142 diacylglycerol cholinephosphotransferase activity ( ); GO:0005094 Rho GDP-dissociation inhibitor activity ( ); GO:0008401 retinoic acid 4-hydroxylase activity ( ); GO:0043025 cell soma ( ); GO:0002312 B cell activation during immune response ( ); GO:0002313 mature B cell differentiation during immune response ( ); GO:0002335 mature B cell differentiation ( ); GO:0009111 vitamin catabolic process ( ); GO:0034375 high-density lipoprotein particle remodeling ( ); GO:0034447 very-low-density lipoprotein particle clearance ( ); GO:0045064 T-helper 2 cell differentiation ( ); GO:0048387 negative regulation of retinoic acid receptor signaling pathway ( ); GO:0051005 negative regulation of lipoprotein lipase activity ( ); GO:0051930 regulation of sensory perception of pain ( ); GO:0051931 regulation of sensory perception ( ); GO:0033256 I-kappaB/NF-kappaB complex ( ); GO:0034363 intermediate-density lipoprotein particle ( ); GO:0001972 retinoic acid binding ( ); ----------------GO-------------- GO:0005789 endoplasmic reticulum membrane ( 0.00103129507624291 ); GO:0044432 endoplasmic reticulum part ( 0.00108373353423005 ); GO:0042175 nuclear envelope-endoplasmic reticulum network ( 0.00118328265990366 ); GO:0002315 marginal zone B cell differentiation ( 0.00226210224702206 ); GO:0006369 termination of RNA polymerase II transcription ( 0.00226210224702206 ); GO:0045415 negative regulation of interleukin-8 biosynthetic process ( 0.00226210224702206 ); GO:0032996 Bcl3-Bcl10 complex ( 0.00226210224702206 ); GO:0034366 spherical high-density lipoprotein particle ( 0.00226210224702206 ); GO:0002266 follicular dendritic cell activation ( 0.00451920084941915 ); GO:0002268 follicular dendritic cell differentiation ( 0.00451920084941915 ); GO:0016264 gap junction assembly ( 0.00451920084941915 ); GO:0042091 interleukin-10 biosynthetic process ( 0.00451920084941915 ); GO:0042832 defense response to protozoan ( 0.00451920084941915 ); GO:0045074 regulation of interleukin-10 biosynthetic process ( 0.00451920084941915 ); GO:0045082 positive regulation of interleukin-10 biosynthetic process ( 0.00451920084941915 ); GO:0033257 Bcl3/NF-kappaB2 complex ( 0.00451920084941915 ); GO:0004605 phosphatidate cytidylyltransferase activity ( 0.00451920084941915 ); GO:0008393 fatty acid (omega-1)-hydroxylase activity ( 0.00451920084941915 ); GO:0018685 alkane 1-monooxygenase activity ( 0.00451920084941915 ); GO:0006898 receptor-mediated endocytosis ( 0.00664470302422145 ); GO:0001562 response to protozoan ( 0.00677130662397929 ); GO:0019730 antimicrobial humoral response ( 0.00677130662397929 ); GO:0031648 protein destabilization ( 0.00677130662397929 ); GO:0034653 retinoic acid catabolic process ( 0.00677130662397929 ); GO:0042363 fat-soluble vitamin catabolic process ( 0.00677130662397929 ); GO:0042536 negative regulation of tumor necrosis factor biosynthetic process ( 0.00677130662397929 ); GO:0045717 negative regulation of fatty acid biosynthetic process ( 0.00677130662397929 ); GO:0045922 negative regulation of fatty acid metabolic process ( 0.00677130662397929 ); GO:0004142 diacylglycerol cholinephosphotransferase activity ( 0.00677130662397929 ); GO:0005094 Rho GDP-dissociation inhibitor activity ( 0.00677130662397929 ); GO:0008401 retinoic acid 4-hydroxylase activity ( 0.00677130662397929 ); GO:0043025 cell soma ( 0.00713039339792743 ); GO:0002312 B cell activation during immune response ( 0.00901843036464867 ); GO:0002313 mature B cell differentiation during immune response ( 0.00901843036464867 ); GO:0002335 mature B cell differentiation ( 0.00901843036464867 ); GO:0009111 vitamin catabolic process ( 0.00901843036464867 ); GO:0034375 high-density lipoprotein particle remodeling ( 0.00901843036464867 ); GO:0034447 very-low-density lipoprotein particle clearance ( 0.00901843036464867 ); GO:0045064 T-helper 2 cell differentiation ( 0.00901843036464867 ); GO:0048387 negative regulation of retinoic acid receptor signaling pathway ( 0.00901843036464867 ); GO:0051005 negative regulation of lipoprotein lipase activity ( 0.00901843036464867 ); GO:0051930 regulation of sensory perception of pain ( 0.00901843036464867 ); GO:0051931 regulation of sensory perception ( 0.00901843036464867 ); GO:0033256 I-kappaB/NF-kappaB complex ( 0.00901843036464867 ); GO:0034363 intermediate-density lipoprotein particle ( 0.00901843036464867 ); GO:0001972 retinoic acid binding ( 0.00901843036464867 ); ----------------KEGG-------------- hsa00830 Retinol metabolism ( 0.00713039339792743 ); hsa03320 PPAR signaling pathway ( 0.0103680055016386 ); ----------------CARTA-------------- ( 0.0157300169811556 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0376916512782805 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.04584505752644 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group17 ========================= ----------------C2-------------- REACTOME_FORMATION_OF_PLATELET_PLUG ( 0.000509377318155317 ); REACTOME_HEMOSTASIS ( 0.00215021968785637 ); REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS ( 0.002512533110351 ); REACTOME_PLATELET_ACTIVATION ( 0.00449539157797709 ); REACTOME_PLATELET_ACTIVATION_TRIGGERS ( 0.0062741739690785 ); REACTOME_GPCR_LIGAND_BINDING ( 0.00728655568441996 ); REACTOME_SIGNALING_BY_PDGF ( 0.00734598282718316 ); KEGG_CARDIAC_MUSCLE_CONTRACTION ( 0.00873337715251606 ); ----------------C3-------------- GGARNTKYCCA_UNKNOWN ( 0.000288208553929629 ); V$OLF1_01 ( 0.00732004320222178 ); ----------------C4-------------- module_92 ( 0.00301678303814767 ); module_55 ( 0.00501419884078821 ); module_88 ( 0.00510549809255276 ); module_2 ( 0.0063469530895641 ); ----------------C5-------------- CELL_SURFACE_RECEPTOR_LINKED_SIGNAL_TRANSDUCTION_GO_0007166 ( 0.00133583281280601 ); G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY ( 0.00389125037537181 ); CELL_CELL_SIGNALING ( 0.00810151402468099 ); ----------------GOSLIM-------------- GO:0004960 thromboxane receptor activity ( 0.00113660002906207 ); GO:0004961 thromboxane A2 receptor activity ( 0.00113660002906207 ); GO:0005576 extracellular region ( 0.00113660002906207 ); GO:0005581 collagen ( 0.00113660002906207 ); GO:0010511 regulation of phosphatidylinositol biosynthetic process ( 0.00113660002906207 ); GO:0010512 negative regulation of phosphatidylinositol biosynthetic process ( 0.00113660002906207 ); GO:0005584 collagen type I ( 0.00113660002906207 ); GO:0031089 platelet dense granule lumen ( 0.00113660002906207 ); GO:0016020 membrane ( 0.00113660002906207 ); GO:0007166 cell surface receptor linked signal transduction ( 0.00113660002906207 ); GO:0008628 induction of apoptosis by hormones ( 0.00113660002906207 ); GO:0035081 induction of programmed cell death by hormones ( 0.00113660002906207 ); GO:0043589 skin morphogenesis ( 0.00113660002906207 ); GO:0004938 alpha2-adrenergic receptor activity ( 0.00113660002906207 ); GO:0005201 extracellular matrix structural constituent ( 0.00113660002906207 ); GO:0010544 negative regulation of platelet activation ( 0.00113660002906207 ); GO:0050919 negative chemotaxis ( 0.00113660002906207 ); ----------------GO-------------- GO:0004960 thromboxane receptor activity ( 0.00201075755290792 ); GO:0004961 thromboxane A2 receptor activity ( 0.00201075755290792 ); GO:0005576 extracellular region ( 0.0021142650326757 ); GO:0005581 collagen ( 0.00224923070423553 ); GO:0010511 regulation of phosphatidylinositol biosynthetic process ( 0.00401757284035464 ); GO:0010512 negative regulation of phosphatidylinositol biosynthetic process ( 0.00401757284035464 ); GO:0005584 collagen type I ( 0.00401757284035464 ); GO:0031089 platelet dense granule lumen ( 0.00401757284035464 ); GO:0016020 membrane ( 0.00406404968297249 ); GO:0007166 cell surface receptor linked signal transduction ( 0.00594068562233901 ); GO:0008628 induction of apoptosis by hormones ( 0.00602045339368973 ); GO:0035081 induction of programmed cell death by hormones ( 0.00602045339368973 ); GO:0043589 skin morphogenesis ( 0.00602045339368973 ); GO:0004938 alpha2-adrenergic receptor activity ( 0.00602045339368973 ); GO:0005201 extracellular matrix structural constituent ( 0.00690795607745281 ); GO:0010544 negative regulation of platelet activation ( 0.00801940673025325 ); GO:0050919 negative chemotaxis ( 0.00801940673025325 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- tidpathway ( 0.0120055617525298 ); sppapathway ( 0.0258344954633349 ); ranklpathway ( 0.0277945870217589 ); myosinpathway ( 0.0394746388724456 ); her2pathway ( 0.0414079662233796 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group19 ========================= ----------------C2-------------- KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION ( 0.00539487223955345 ); KEGG_GLYCEROPHOSPHOLIPID_METABOLISM ( 0.00925459301697247 ); ----------------C3-------------- AAGCAAT,MIR-137 ( 0.00469452803109816 ); CAGTATT,MIR-200B,MIR-200C,MIR-429 ( 0.00665761975171149 ); V$HAND1E47_01 ( 0.00672603689282404 ); ATGGYGGA_UNKNOWN ( 0.0078630916151489 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0016199 axon midline choice point recognition ( ); GO:0045171 intercellular bridge ( ); GO:0004306 ethanolamine-phosphate cytidylyltransferase activity ( ); GO:0008187 poly-pyrimidine tract binding ( ); GO:0019782 ISG15 activating enzyme activity ( ); GO:0032028 myosin head/neck binding ( ); GO:0001956 positive regulation of neurotransmitter secretion ( ); GO:0017077 oxidative phosphorylation uncoupler activity ( ); GO:0031386 protein tag ( ); GO:0043008 ATP-dependent protein binding ( ); GO:0015992 proton transport ( ); GO:0006420 arginyl-tRNA aminoacylation ( ); GO:0009629 response to gravity ( ); GO:0016081 synaptic vesicle docking during exocytosis ( ); GO:0016198 axon choice point recognition ( ); GO:0042641 actomyosin ( ); GO:0004814 arginine-tRNA ligase activity ( ); GO:0019855 calcium channel inhibitor activity ( ); GO:0006818 hydrogen transport ( ); GO:0019992 diacylglycerol binding ( ); GO:0032020 ISG15-protein conjugation ( ); GO:0051590 positive regulation of neurotransmitter transport ( ); GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism ( ); GO:0007411 axon guidance ( ); GO:0000303 response to superoxide ( ); GO:0006930 substrate-bound cell migration, cell extension ( ); GO:0005546 phosphatidylinositol-4,5-bisphosphate binding ( ); GO:0032036 myosin heavy chain binding ( ); ----------------GO-------------- GO:0016199 axon midline choice point recognition ( 0.00196048861408538 ); GO:0045171 intercellular bridge ( 0.00196048861408538 ); GO:0004306 ethanolamine-phosphate cytidylyltransferase activity ( 0.00196048861408538 ); GO:0008187 poly-pyrimidine tract binding ( 0.00196048861408538 ); GO:0019782 ISG15 activating enzyme activity ( 0.00196048861408538 ); GO:0032028 myosin head/neck binding ( 0.00196048861408538 ); GO:0001956 positive regulation of neurotransmitter secretion ( 0.00391723207598194 ); GO:0017077 oxidative phosphorylation uncoupler activity ( 0.00391723207598194 ); GO:0031386 protein tag ( 0.00391723207598194 ); GO:0043008 ATP-dependent protein binding ( 0.00391723207598194 ); GO:0015992 proton transport ( 0.00577646978037832 ); GO:0006420 arginyl-tRNA aminoacylation ( 0.00587023735218917 ); GO:0009629 response to gravity ( 0.00587023735218917 ); GO:0016081 synaptic vesicle docking during exocytosis ( 0.00587023735218917 ); GO:0016198 axon choice point recognition ( 0.00587023735218917 ); GO:0042641 actomyosin ( 0.00587023735218917 ); GO:0004814 arginine-tRNA ligase activity ( 0.00587023735218917 ); GO:0019855 calcium channel inhibitor activity ( 0.00587023735218917 ); GO:0006818 hydrogen transport ( 0.00617010263351795 ); GO:0019992 diacylglycerol binding ( 0.00742226397553004 ); GO:0032020 ISG15-protein conjugation ( 0.00781951139659631 ); GO:0051590 positive regulation of neurotransmitter transport ( 0.00781951139659631 ); GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism ( 0.00781951139659631 ); GO:0007411 axon guidance ( 0.00877934843737351 ); GO:0000303 response to superoxide ( 0.00976506115050746 ); GO:0006930 substrate-bound cell migration, cell extension ( 0.00976506115050746 ); GO:0005546 phosphatidylinositol-4,5-bisphosphate binding ( 0.00976506115050746 ); GO:0032036 myosin heavy chain binding ( 0.00976506115050746 ); ----------------KEGG-------------- hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0044941622411704 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0044941622411704 ); hsa00440 Aminophosphonate metabolism ( 0.0213605367061442 ); ----------------CARTA-------------- stat3pathway ( 0.00976506115050746 ); gata3pathway ( 0.0290172408436036 ); gcrpathway ( 0.0479045343109433 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group40 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_147 ( 0.00091508256726992 ); module_195 ( 0.00216735580369208 ); module_356 ( 0.0023071164890543 ); ----------------C5-------------- HYDRO_LYASE_ACTIVITY ( 0.00121010616247225 ); CARBON_OXYGEN_LYASE_ACTIVITY ( 0.00159543219492968 ); BIOSYNTHETIC_PROCESS ( 0.00168165164086668 ); NUCLEAR_CHROMOSOME_PART ( 0.00191787666659279 ); RESPONSE_TO_STRESS ( 0.00236198733704596 ); CELLULAR_BIOSYNTHETIC_PROCESS ( 0.00281261173382941 ); GOLGI_VESICLE_TRANSPORT ( 0.0036382868641533 ); HELICASE_ACTIVITY ( 0.00394852952340981 ); NUCLEAR_CHROMOSOME ( 0.00477596160422546 ); LYASE_ACTIVITY ( 0.00747624970610343 ); ----------------GOSLIM-------------- GO:0006890 retrograde vesicle-mediated transport, Golgi to ER ( 0.00358990882469892 ); GO:0006950 response to stress ( 0.00641556174990039 ); GO:0033554 cellular response to stress ( 0.00358990882469892 ); GO:0051716 cellular response to stimulus ( 0.00641556174990039 ); GO:0004655 porphobilinogen synthase activity ( 0.00358990882469892 ); GO:0005524 ATP binding ( 0.00641556174990039 ); GO:0009451 RNA modification ( 0.00358990882469892 ); GO:0032559 adenyl ribonucleotide binding ( 0.00641556174990039 ); GO:0016836 hydro-lyase activity ( 0.00358990882469892 ); GO:0000166 nucleotide binding ( 0.00641556174990039 ); GO:0030554 adenyl nucleotide binding ( 0.00358990882469892 ); GO:0034067 protein localization in Golgi apparatus ( 0.00641556174990039 ); GO:0043200 response to amino acid stimulus ( 0.00358990882469892 ); GO:0000248 C-5 sterol desaturase activity ( 0.00641556174990039 ); GO:0047134 protein-disulfide reductase activity ( 0.00358990882469892 ); GO:0016835 carbon-oxygen lyase activity ( 0.00641556174990039 ); GO:0006419 alanyl-tRNA aminoacylation ( 0.00358990882469892 ); GO:0004813 alanine-tRNA ligase activity ( 0.00641556174990039 ); GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity ( 0.00358990882469892 ); GO:0006986 response to unfolded protein ( 0.00641556174990039 ); GO:0006636 unsaturated fatty acid biosynthetic process ( 0.00358990882469892 ); GO:0006972 hyperosmotic response ( 0.00641556174990039 ); GO:0031167 rRNA methylation ( 0.00358990882469892 ); GO:0033559 unsaturated fatty acid metabolic process ( 0.00641556174990039 ); GO:0005662 DNA replication factor A complex ( 0.00358990882469892 ); GO:0004791 thioredoxin-disulfide reductase activity ( 0.00641556174990039 ); GO:0051789 response to protein stimulus ( 0.00358990882469892 ); GO:0032553 ribonucleotide binding ( 0.00641556174990039 ); GO:0032555 purine ribonucleotide binding ( 0.00358990882469892 ); GO:0044454 nuclear chromosome part ( 0.00641556174990039 ); GO:0001101 response to acid ( 0.00358990882469892 ); GO:0048873 homeostasis of number of cells within a tissue ( 0.00641556174990039 ); GO:0008526 phosphatidylinositol transporter activity ( 0.00358990882469892 ); GO:0006730 one-carbon compound metabolic process ( 0.00641556174990039 ); ----------------GO-------------- GO:0006890 retrograde vesicle-mediated transport, Golgi to ER ( 0.000533231701010403 ); GO:0006950 response to stress ( 0.000865393002937981 ); GO:0033554 cellular response to stress ( 0.00102917938172837 ); GO:0051716 cellular response to stimulus ( 0.00136692468029948 ); GO:0004655 porphobilinogen synthase activity ( 0.00191021967526228 ); GO:0005524 ATP binding ( 0.00195160248834649 ); GO:0009451 RNA modification ( 0.00214859029344829 ); GO:0032559 adenyl ribonucleotide binding ( 0.00214928849331605 ); GO:0016836 hydro-lyase activity ( 0.00264739583022623 ); GO:0000166 nucleotide binding ( 0.00299501162354494 ); GO:0030554 adenyl nucleotide binding ( 0.00303317932678792 ); GO:0034067 protein localization in Golgi apparatus ( 0.00381688625742305 ); GO:0043200 response to amino acid stimulus ( 0.00381688625742305 ); GO:0000248 C-5 sterol desaturase activity ( 0.00381688625742305 ); GO:0047134 protein-disulfide reductase activity ( 0.00381688625742305 ); GO:0016835 carbon-oxygen lyase activity ( 0.0041081156352618 ); GO:0006419 alanyl-tRNA aminoacylation ( 0.005720006177096 ); GO:0004813 alanine-tRNA ligase activity ( 0.005720006177096 ); GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity ( 0.005720006177096 ); GO:0006986 response to unfolded protein ( 0.00705664429878446 ); GO:0006636 unsaturated fatty acid biosynthetic process ( 0.00761958585358036 ); GO:0006972 hyperosmotic response ( 0.00761958585358036 ); GO:0031167 rRNA methylation ( 0.00761958585358036 ); GO:0033559 unsaturated fatty acid metabolic process ( 0.00761958585358036 ); GO:0005662 DNA replication factor A complex ( 0.00761958585358036 ); GO:0004791 thioredoxin-disulfide reductase activity ( 0.00761958585358036 ); GO:0051789 response to protein stimulus ( 0.00834852906410622 ); GO:0032553 ribonucleotide binding ( 0.0085635627524749 ); GO:0032555 purine ribonucleotide binding ( 0.0085635627524749 ); GO:0044454 nuclear chromosome part ( 0.00903133652186926 ); GO:0001101 response to acid ( 0.0095156316948779 ); GO:0048873 homeostasis of number of cells within a tissue ( 0.0095156316948779 ); GO:0008526 phosphatidylinositol transporter activity ( 0.0095156316948779 ); GO:0006730 one-carbon compound metabolic process ( 0.00973833811457639 ); ----------------KEGG-------------- hsa01040 Biosynthesis of unsaturated fatty acids ( 0.0393769490130574 ); hsa03430 Mismatch repair ( 0.0430474090405675 ); hsa00910 Nitrogen metabolism ( 0.0448775146498503 ); ----------------CARTA-------------- mta3pathway ( 0.030140724265507 ); her2pathway ( 0.0393769490130574 ); mef2dpathway ( 0.0448775146498503 ); ----------------RBP-------------- ( 0.00203993346510271 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3089 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$GRE_C ( 0.000728737836167072 ); TTGCCAA,MIR-182 ( 0.00162630030809976 ); TAATGTG,MIR-323 ( 0.00192253162176876 ); TCCATTKW_UNKNOWN ( 0.00444614164580768 ); CAGNYGKNAAA_UNKNOWN ( 0.00453244404364764 ); TACAATC,MIR-508 ( 0.00469799393592385 ); V$STAT6_01 ( 0.00540314727869703 ); CAGTATT,MIR-200B,MIR-200C,MIR-429 ( 0.00550985329873892 ); V$AFP1_Q6 ( 0.00572062243628978 ); GTTTGTT,MIR-495 ( 0.00638872790771694 ); GTCGATC,MIR-369-5P ( 0.00741963009816127 ); ----------------C4-------------- module_8 ( 0.000860191240098935 ); GNF2_HAT1 ( 0.00345197660906478 ); module_17 ( 0.0038163314464303 ); module_18 ( 0.00828940784994182 ); GNF2_SMC4L1 ( 0.00879834348784957 ); ----------------C5-------------- RNA_POLYMERASE_II_TRANSCRIPTION_MEDIATOR_ACTIVITY ( 0.000259188592477628 ); PROTEIN_METABOLIC_PROCESS ( 0.000261066011041594 ); PROTEIN_MODIFICATION_PROCESS ( 0.000817390128745063 ); BIOPOLYMER_MODIFICATION ( 0.000943518411744853 ); POST_TRANSLATIONAL_PROTEIN_MODIFICATION ( 0.00153160253399884 ); GENERAL_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00161190307927336 ); CELLULAR_PROTEIN_METABOLIC_PROCESS ( 0.00335089411208867 ); CELLULAR_MACROMOLECULE_METABOLIC_PROCESS ( 0.0035993302940879 ); RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00458602499106542 ); N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION ( 0.00926615197891767 ); ----------------GOSLIM-------------- GO:0006508 proteolysis ( 0.000949394524039715 ); GO:0016455 RNA polymerase II transcription mediator activity ( 0.000949394524039715 ); GO:0006511 ubiquitin-dependent protein catabolic process ( 0.000949394524039715 ); GO:0019941 modification-dependent protein catabolic process ( 0.000949394524039715 ); GO:0043632 modification-dependent macromolecule catabolic process ( 0.000949394524039715 ); GO:0051603 proteolysis involved in cellular protein catabolic process ( 0.000949394524039715 ); GO:0034962 cellular biopolymer catabolic process ( 0.000949394524039715 ); GO:0044257 cellular protein catabolic process ( 0.000949394524039715 ); GO:0016874 ligase activity ( 0.000949394524039715 ); GO:0030163 protein catabolic process ( 0.000949394524039715 ); GO:0043412 biopolymer modification ( 0.000949394524039715 ); GO:0043285 biopolymer catabolic process ( 0.000949394524039715 ); GO:0044265 cellular macromolecule catabolic process ( 0.000949394524039715 ); GO:0016251 general RNA polymerase II transcription factor activity ( 0.000949394524039715 ); GO:0009057 macromolecule catabolic process ( 0.000949394524039715 ); GO:0043414 biopolymer methylation ( 0.000949394524039715 ); GO:0044267 cellular protein metabolic process ( 0.000949394524039715 ); GO:0006464 protein modification process ( 0.000949394524039715 ); GO:0019538 protein metabolic process ( 0.000949394524039715 ); GO:0043687 post-translational protein modification ( 0.000949394524039715 ); GO:0044260 cellular macromolecule metabolic process ( 0.000949394524039715 ); GO:0032259 methylation ( 0.000949394524039715 ); GO:0003960 NADPH:quinone reductase activity ( 0.000949394524039715 ); GO:0003963 RNA-3'-phosphate cyclase activity ( 0.000949394524039715 ); GO:0004905 type I interferon receptor activity ( 0.000949394524039715 ); GO:0016426 tRNA (adenine)-methyltransferase activity ( 0.000949394524039715 ); GO:0016429 tRNA (adenine-N1-)-methyltransferase activity ( 0.000949394524039715 ); GO:0019962 type I interferon binding ( 0.000949394524039715 ); GO:0043170 macromolecule metabolic process ( 0.000949394524039715 ); GO:0008150 biological_process ( 0.000949394524039715 ); GO:0016881 acid-amino acid ligase activity ( 0.000949394524039715 ); GO:0004702 receptor signaling protein serine/threonine kinase activity ( 0.000949394524039715 ); GO:0018206 peptidyl-methionine modification ( 0.000949394524039715 ); GO:0030488 tRNA methylation ( 0.000949394524039715 ); GO:0045116 protein neddylation ( 0.000949394524039715 ); GO:0048935 peripheral nervous system neuron development ( 0.000949394524039715 ); GO:0016879 ligase activity, forming carbon-nitrogen bonds ( 0.000949394524039715 ); GO:0034960 cellular biopolymer metabolic process ( 0.000949394524039715 ); GO:0003702 RNA polymerase II transcription factor activity ( 0.000949394524039715 ); GO:0043283 biopolymer metabolic process ( 0.000949394524039715 ); GO:0006358 regulation of transcription from RNA polymerase II promoter, global ( 0.000949394524039715 ); GO:0048934 peripheral nervous system neuron differentiation ( 0.000949394524039715 ); GO:0004904 interferon receptor activity ( 0.000949394524039715 ); GO:0019961 interferon binding ( 0.000949394524039715 ); GO:0034235 GPI anchor binding ( 0.000949394524039715 ); GO:0008757 S-adenosylmethionine-dependent methyltransferase activity ( 0.000949394524039715 ); GO:0044248 cellular catabolic process ( 0.000949394524039715 ); GO:0006730 one-carbon compound metabolic process ( 0.000949394524039715 ); GO:0042765 GPI-anchor transamidase complex ( 0.000949394524039715 ); GO:0003923 GPI-anchor transamidase activity ( 0.000949394524039715 ); GO:0016886 ligase activity, forming phosphoric ester bonds ( 0.000949394524039715 ); ----------------GO-------------- GO:0006508 proteolysis ( 0.000346048656660559 ); GO:0016455 RNA polymerase II transcription mediator activity ( 0.000397351886047663 ); GO:0006511 ubiquitin-dependent protein catabolic process ( 0.000404365826126419 ); GO:0019941 modification-dependent protein catabolic process ( 0.000408428088255603 ); GO:0043632 modification-dependent macromolecule catabolic process ( 0.000408428088255603 ); GO:0051603 proteolysis involved in cellular protein catabolic process ( 0.000408428088255603 ); GO:0034962 cellular biopolymer catabolic process ( 0.000416648716477467 ); GO:0044257 cellular protein catabolic process ( 0.000416648716477467 ); GO:0016874 ligase activity ( 0.000530766820836735 ); GO:0030163 protein catabolic process ( 0.000530789243998535 ); GO:0043412 biopolymer modification ( 0.000896496135557693 ); GO:0043285 biopolymer catabolic process ( 0.00123096658337175 ); GO:0044265 cellular macromolecule catabolic process ( 0.00192162669028651 ); GO:0016251 general RNA polymerase II transcription factor activity ( 0.00226863695764693 ); GO:0009057 macromolecule catabolic process ( 0.00239381236080633 ); GO:0043414 biopolymer methylation ( 0.00251124379540524 ); GO:0044267 cellular protein metabolic process ( 0.00280395739792232 ); GO:0006464 protein modification process ( 0.00290764167148704 ); GO:0019538 protein metabolic process ( 0.00301197508508531 ); GO:0043687 post-translational protein modification ( 0.00306725269045932 ); GO:0044260 cellular macromolecule metabolic process ( 0.00320714481426415 ); GO:0032259 methylation ( 0.00330894673064847 ); GO:0003960 NADPH:quinone reductase activity ( 0.00371653538467775 ); GO:0003963 RNA-3'-phosphate cyclase activity ( 0.00371653538467775 ); GO:0004905 type I interferon receptor activity ( 0.00371653538467775 ); GO:0016426 tRNA (adenine)-methyltransferase activity ( 0.00371653538467775 ); GO:0016429 tRNA (adenine-N1-)-methyltransferase activity ( 0.00371653538467775 ); GO:0019962 type I interferon binding ( 0.00371653538467775 ); GO:0043170 macromolecule metabolic process ( 0.00378278213210081 ); GO:0008150 biological_process ( 0.00393447360360697 ); GO:0016881 acid-amino acid ligase activity ( 0.0040422430162166 ); GO:0004702 receptor signaling protein serine/threonine kinase activity ( 0.00469799393592385 ); GO:0018206 peptidyl-methionine modification ( 0.00556975986764852 ); GO:0030488 tRNA methylation ( 0.00556975986764852 ); GO:0045116 protein neddylation ( 0.00556975986764852 ); GO:0048935 peripheral nervous system neuron development ( 0.00556975986764852 ); GO:0016879 ligase activity, forming carbon-nitrogen bonds ( 0.00621752551286884 ); GO:0034960 cellular biopolymer metabolic process ( 0.00690573610396466 ); GO:0003702 RNA polymerase II transcription factor activity ( 0.00691920882522937 ); GO:0043283 biopolymer metabolic process ( 0.00733133052961187 ); GO:0006358 regulation of transcription from RNA polymerase II promoter, global ( 0.00741963009816127 ); GO:0048934 peripheral nervous system neuron differentiation ( 0.00741963009816127 ); GO:0004904 interferon receptor activity ( 0.00741963009816127 ); GO:0019961 interferon binding ( 0.00741963009816127 ); GO:0034235 GPI anchor binding ( 0.00741963009816127 ); GO:0008757 S-adenosylmethionine-dependent methyltransferase activity ( 0.00835779892800481 ); GO:0044248 cellular catabolic process ( 0.00845985467316269 ); GO:0006730 one-carbon compound metabolic process ( 0.00924911830767498 ); GO:0042765 GPI-anchor transamidase complex ( 0.00926615197891767 ); GO:0003923 GPI-anchor transamidase activity ( 0.00926615197891767 ); GO:0016886 ligase activity, forming phosphoric ester bonds ( 0.00926615197891767 ); ----------------KEGG-------------- ( 0.041937647048329 ); ----------------CARTA-------------- fbw7pathway ( 0.0111093314025291 ); p27pathway ( 0.0129491742515311 ); ptc1pathway ( 0.016618873705582 ); pkcpathway ( 0.0202752972005094 ); nthipathway ( 0.0329689040373871 ); raccycdpathway ( 0.0455024375100628 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 4.1269011727326e-07 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 1.23724851621829e-05 ); ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 0.00224492515102717 ); QKI_PAR-CLIP_(Hafner_2010) ( 0.00351184705653995 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.00596314912361483 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0218644353149257 ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_ALL ( 0.00659492375539335 ); ARE_C3 ( 0.00766631708438945 ); ============================ group2999 ========================= ----------------C2-------------- BIOCARTA_VEGF_PATHWAY ( 0.0012536211695132 ); BIOCARTA_NO1_PATHWAY ( 0.0013416393083473 ); KEGG_VEGF_SIGNALING_PATHWAY ( 0.00813289170174883 ); ----------------C3-------------- SNACANNNYSYAGA_UNKNOWN ( 0.0042948859082696 ); AACYNNNNTTCCS_UNKNOWN ( 0.00598246998625206 ); ----------------C4-------------- module_522 ( 0.00152630321331872 ); module_7 ( 0.0076500185692983 ); ----------------C5-------------- SULFOTRANSFERASE_ACTIVITY ( 0.00100694386603201 ); TRANSFERASE_ACTIVITY__TRANSFERRING_SULFUR_CONTAINING_GROUPS ( 0.0013416393083473 ); SULFUR_METABOLIC_PROCESS ( 0.00182471667607684 ); ----------------GOSLIM-------------- GO:0016358 dendrite development ( ); GO:0022602 ovulation cycle process ( ); GO:0042698 ovulation cycle ( ); GO:0008585 female gonad development ( ); GO:0014738 regulation of muscle hyperplasia ( ); GO:0014740 negative regulation of muscle hyperplasia ( ); GO:0014900 muscle hyperplasia ( ); GO:0031284 positive regulation of guanylate cyclase activity ( ); GO:0034504 protein localization in nucleus ( ); GO:0046545 development of primary female sexual characteristics ( ); GO:0046660 female sex differentiation ( ); GO:0000267 cell fraction ( ); GO:0008146 sulfotransferase activity ( ); GO:0014806 smooth muscle hyperplasia ( ); GO:0031282 regulation of guanylate cyclase activity ( ); GO:0003912 DNA nucleotidylexotransferase activity ( ); GO:0005624 membrane fraction ( ); GO:0016782 transferase activity, transferring sulfur-containing groups ( ); GO:0005626 insoluble fraction ( ); GO:0030324 lung development ( ); GO:0032504 multicellular organism reproduction ( ); GO:0048609 reproductive process in a multicellular organism ( ); GO:0043267 negative regulation of potassium ion transport ( ); GO:0050773 regulation of dendrite development ( ); GO:0042641 actomyosin ( ); GO:0004517 nitric-oxide synthase activity ( ); GO:0034617 tetrahydrobiopterin binding ( ); GO:0034618 arginine binding ( ); GO:0047756 chondroitin 4-sulfotransferase activity ( ); GO:0030323 respiratory tube development ( ); GO:0008406 gonad development ( ); GO:0048608 reproductive structure development ( ); GO:0010544 negative regulation of platelet activation ( ); GO:0014745 negative regulation of muscle adaptation ( ); GO:0014805 smooth muscle adaptation ( ); GO:0043113 receptor clustering ( ); GO:0043129 surfactant homeostasis ( ); GO:0048875 chemical homeostasis within a tissue ( ); GO:0045137 development of primary sexual characteristics ( ); GO:0048511 rhythmic process ( ); GO:0003100 regulation of systemic arterial blood pressure by endothelin ( ); GO:0030177 positive regulation of Wnt receptor signaling pathway ( ); GO:0030823 regulation of cGMP metabolic process ( ); GO:0030826 regulation of cGMP biosynthetic process ( ); GO:0014701 junctional sarcoplasmic reticulum membrane ( ); GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity ( ); GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity ( ); GO:0034481 chondroitin sulfotransferase activity ( ); GO:0065009 regulation of molecular function ( ); GO:0006790 sulfur metabolic process ( ); ----------------GO-------------- GO:0016358 dendrite development ( 0.000718968898672833 ); GO:0022602 ovulation cycle process ( 0.0013416393083473 ); GO:0042698 ovulation cycle ( 0.00143253669726872 ); GO:0008585 female gonad development ( 0.00172240326216572 ); GO:0014738 regulation of muscle hyperplasia ( 0.0018096817976172 ); GO:0014740 negative regulation of muscle hyperplasia ( 0.0018096817976172 ); GO:0014900 muscle hyperplasia ( 0.0018096817976172 ); GO:0031284 positive regulation of guanylate cyclase activity ( 0.0018096817976172 ); GO:0034504 protein localization in nucleus ( 0.0018096817976172 ); GO:0046545 development of primary female sexual characteristics ( 0.0020378201753854 ); GO:0046660 female sex differentiation ( 0.0020378201753854 ); GO:0000267 cell fraction ( 0.00230281714504926 ); GO:0008146 sulfotransferase activity ( 0.00313468416269651 ); GO:0014806 smooth muscle hyperplasia ( 0.00361617945774662 ); GO:0031282 regulation of guanylate cyclase activity ( 0.00361617945774662 ); GO:0003912 DNA nucleotidylexotransferase activity ( 0.00361617945774662 ); GO:0005624 membrane fraction ( 0.00369676158076491 ); GO:0016782 transferase activity, transferring sulfur-containing groups ( 0.00398878439967497 ); GO:0005626 insoluble fraction ( 0.00415026594705579 ); GO:0030324 lung development ( 0.0052763236041672 ); GO:0032504 multicellular organism reproduction ( 0.0052763236041672 ); GO:0048609 reproductive process in a multicellular organism ( 0.0052763236041672 ); GO:0043267 negative regulation of potassium ion transport ( 0.00541949842308331 ); GO:0050773 regulation of dendrite development ( 0.00541949842308331 ); GO:0042641 actomyosin ( 0.00541949842308331 ); GO:0004517 nitric-oxide synthase activity ( 0.00541949842308331 ); GO:0034617 tetrahydrobiopterin binding ( 0.00541949842308331 ); GO:0034618 arginine binding ( 0.00541949842308331 ); GO:0047756 chondroitin 4-sulfotransferase activity ( 0.00541949842308331 ); GO:0030323 respiratory tube development ( 0.00562426144295888 ); GO:0008406 gonad development ( 0.00635087464682484 ); GO:0048608 reproductive structure development ( 0.0067294012165563 ); GO:0010544 negative regulation of platelet activation ( 0.00721964412729514 ); GO:0014745 negative regulation of muscle adaptation ( 0.00721964412729514 ); GO:0014805 smooth muscle adaptation ( 0.00721964412729514 ); GO:0043113 receptor clustering ( 0.00721964412729514 ); GO:0043129 surfactant homeostasis ( 0.00721964412729514 ); GO:0048875 chemical homeostasis within a tissue ( 0.00721964412729514 ); GO:0045137 development of primary sexual characteristics ( 0.00855605861934845 ); GO:0048511 rhythmic process ( 0.00855605861934845 ); GO:0003100 regulation of systemic arterial blood pressure by endothelin ( 0.00901662199503217 ); GO:0030177 positive regulation of Wnt receptor signaling pathway ( 0.00901662199503217 ); GO:0030823 regulation of cGMP metabolic process ( 0.00901662199503217 ); GO:0030826 regulation of cGMP biosynthetic process ( 0.00901662199503217 ); GO:0014701 junctional sarcoplasmic reticulum membrane ( 0.00901662199503217 ); GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity ( 0.00901662199503217 ); GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity ( 0.00901662199503217 ); GO:0034481 chondroitin sulfotransferase activity ( 0.00901662199503217 ); GO:0065009 regulation of molecular function ( 0.00942805573785377 ); GO:0006790 sulfur metabolic process ( 0.00943148207391666 ); ----------------KEGG-------------- hsa04370 VEGF signaling pathway ( 0.00771951740417165 ); hsa00232 Caffeine metabolism ( 0.0126010958746927 ); hsa00920 Sulfur metabolism ( 0.0232790508182448 ); hsa03450 Non-homologous end-joining ( 0.0232790508182448 ); hsa00532 Chondroitin sulfate biosynthesis ( 0.0355948109769735 ); ----------------CARTA-------------- ranklpathway ( 0.0250477607865824 ); fibrinolysispathway ( 0.0320915130536014 ); rac1pathway ( 0.0355948109769735 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group8 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- G_PROTEIN_SIGNALING__COUPLED_TO_CAMP_NUCLEOTIDE_SECOND_MESSENGER ( 0.00532242919549093 ); CAMP_MEDIATED_SIGNALING ( 0.00549089261481656 ); ----------------GOSLIM-------------- GO:0007194 negative regulation of adenylate cyclase activity ( ); GO:0031280 negative regulation of cyclase activity ( ); GO:0051350 negative regulation of lyase activity ( ); GO:0019227 action potential propagation ( ); GO:0030273 melanin-concentrating hormone receptor activity ( ); GO:0004473 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity ( ); GO:0004938 alpha2-adrenergic receptor activity ( ); GO:0019763 immunoglobulin receptor activity ( ); GO:0045761 regulation of adenylate cyclase activity ( ); GO:0031279 regulation of cyclase activity ( ); GO:0051339 regulation of lyase activity ( ); GO:0004470 malic enzyme activity ( ); GO:0032190 acrosin binding ( ); GO:0030817 regulation of cAMP biosynthetic process ( ); GO:0030814 regulation of cAMP metabolic process ( ); GO:0030802 regulation of cyclic nucleotide biosynthetic process ( ); GO:0030808 regulation of nucleotide biosynthetic process ( ); GO:0030799 regulation of cyclic nucleotide metabolic process ( ); GO:0006140 regulation of nucleotide metabolic process ( ); GO:0006171 cAMP biosynthetic process ( ); ----------------GO-------------- GO:0007194 negative regulation of adenylate cyclase activity ( 0.00144295519905206 ); GO:0031280 negative regulation of cyclase activity ( 0.00144295519905206 ); GO:0051350 negative regulation of lyase activity ( 0.00144295519905206 ); GO:0019227 action potential propagation ( 0.00175941285879455 ); GO:0030273 melanin-concentrating hormone receptor activity ( 0.00175941285879455 ); GO:0004473 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity ( 0.00351581847662741 ); GO:0004938 alpha2-adrenergic receptor activity ( 0.00526922184263856 ); GO:0019763 immunoglobulin receptor activity ( 0.00526922184263856 ); GO:0045761 regulation of adenylate cyclase activity ( 0.00618898345923011 ); GO:0031279 regulation of cyclase activity ( 0.00655245162870666 ); GO:0051339 regulation of lyase activity ( 0.00692544438007268 ); GO:0004470 malic enzyme activity ( 0.0070196279379382 ); GO:0032190 acrosin binding ( 0.0070196279379382 ); GO:0030817 regulation of cAMP biosynthetic process ( 0.00711549136145469 ); GO:0030814 regulation of cAMP metabolic process ( 0.00750264449310383 ); GO:0030802 regulation of cyclic nucleotide biosynthetic process ( 0.00810089660835348 ); GO:0030808 regulation of nucleotide biosynthetic process ( 0.00810089660835348 ); GO:0030799 regulation of cyclic nucleotide metabolic process ( 0.0085113158317363 ); GO:0006140 regulation of nucleotide metabolic process ( 0.00914415590403145 ); GO:0006171 cAMP biosynthetic process ( 0.00914415590403145 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.0277925161886522 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2967 ========================= ----------------C2-------------- BIOCARTA_VIP_PATHWAY ( 1.26166538740379e-05 ); KEGG_APOPTOSIS ( 0.000477904217702365 ); BIOCARTA_NOS1_PATHWAY ( 0.00061839260111485 ); REACTOME_DARPP32_EVENTS ( 0.000951766523057527 ); BIOCARTA_GPCR_PATHWAY ( 0.00162845512027639 ); BIOCARTA_FMLP_PATHWAY ( 0.00172524530144103 ); BIOCARTA_TCR_PATHWAY ( 0.002839104268989 ); KEGG_CALCIUM_SIGNALING_PATHWAY ( 0.00367701437966119 ); BIOCARTA_NFAT_PATHWAY ( 0.0039171367795741 ); KEGG_LONG_TERM_POTENTIATION ( 0.00673776165937865 ); KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY ( 0.0076997338887285 ); REACTOME_OPIOID_SIGNALLING ( 0.00914415590403145 ); ----------------C3-------------- AGGTGCA,MIR-500 ( 0.00871997593422605 ); AGTGCGT,MIR-521 ( 0.0087670417356237 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0045083 negative regulation of interleukin-12 biosynthetic process ( ); GO:0004333 fumarate hydratase activity ( ); GO:0042835 BRE binding ( ); GO:0046625 sphingolipid binding ( ); GO:0048155 S100 alpha binding ( ); GO:0006106 fumarate metabolic process ( ); GO:0016246 RNA interference ( ); GO:0032372 negative regulation of sterol transport ( ); GO:0032375 negative regulation of cholesterol transport ( ); GO:0048038 quinone binding ( ); GO:0032232 negative regulation of actin filament bundle formation ( ); GO:0051497 negative regulation of stress fiber formation ( ); GO:0033256 I-kappaB/NF-kappaB complex ( ); GO:0000900 translation repressor activity, nucleic acid binding ( ); GO:0005499 vitamin D binding ( ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( ); GO:0042090 interleukin-12 biosynthetic process ( ); GO:0042769 DNA damage response, detection of DNA damage ( ); GO:0045075 regulation of interleukin-12 biosynthetic process ( ); GO:0045822 negative regulation of heart contraction ( ); GO:0048873 homeostasis of number of cells within a tissue ( ); GO:0045239 tricarboxylic acid cycle enzyme complex ( ); GO:0008131 amine oxidase activity ( ); GO:0046790 virion binding ( ); ----------------GO-------------- GO:0045083 negative regulation of interleukin-12 biosynthetic process ( 0.00175941285879455 ); GO:0004333 fumarate hydratase activity ( 0.00175941285879455 ); GO:0042835 BRE binding ( 0.00175941285879455 ); GO:0046625 sphingolipid binding ( 0.00175941285879455 ); GO:0048155 S100 alpha binding ( 0.00351581847662741 ); GO:0006106 fumarate metabolic process ( 0.00526922184263856 ); GO:0016246 RNA interference ( 0.00526922184263856 ); GO:0032372 negative regulation of sterol transport ( 0.00526922184263856 ); GO:0032375 negative regulation of cholesterol transport ( 0.00526922184263856 ); GO:0048038 quinone binding ( 0.00526922184263856 ); GO:0032232 negative regulation of actin filament bundle formation ( 0.0070196279379382 ); GO:0051497 negative regulation of stress fiber formation ( 0.0070196279379382 ); GO:0033256 I-kappaB/NF-kappaB complex ( 0.0070196279379382 ); GO:0000900 translation repressor activity, nucleic acid binding ( 0.0070196279379382 ); GO:0005499 vitamin D binding ( 0.0070196279379382 ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( 0.00787631882804472 ); GO:0042090 interleukin-12 biosynthetic process ( 0.0087670417356237 ); GO:0042769 DNA damage response, detection of DNA damage ( 0.0087670417356237 ); GO:0045075 regulation of interleukin-12 biosynthetic process ( 0.0087670417356237 ); GO:0045822 negative regulation of heart contraction ( 0.0087670417356237 ); GO:0048873 homeostasis of number of cells within a tissue ( 0.0087670417356237 ); GO:0045239 tricarboxylic acid cycle enzyme complex ( 0.0087670417356237 ); GO:0008131 amine oxidase activity ( 0.0087670417356237 ); GO:0046790 virion binding ( 0.0087670417356237 ); ----------------KEGG-------------- hsa04210 Apoptosis ( 0.000494176511031686 ); hsa04020 Calcium signaling pathway ( 0.00373557008264924 ); hsa04662 B cell receptor signaling pathway ( 0.00583510772479384 ); hsa04720 Long-term potentiation ( 0.00692544438007268 ); hsa04010 MAPK signaling pathway ( 0.0111706315152822 ); hsa04660 T cell receptor signaling pathway ( 0.0118778832448227 ); hsa00720 Reductive carboxylate cycle (CO2 fixation) ( 0.0174593997588282 ); hsa04310 Wnt signaling pathway ( 0.0289163574269708 ); hsa05010 Alzheimer's disease ( 0.0317940718369219 ); hsa00220 Urea cycle and metabolism of amino groups ( 0.0498200742195269 ); ----------------CARTA-------------- raspathway ( 0.0105114682007912 ); plcepathway ( 0.0139913789540207 ); sppapathway ( 0.0226392235398692 ); her2pathway ( 0.0363227372002584 ); malpathway ( 0.0397144288952402 ); ----------------RBP-------------- ( ); ----------------immu-------------- BCR_signalling_pathway ( 0.00750264449310383 ); TCR_signalling_pathway ( 0.0126108172376082 ); ----------------ARE-------------- ( 0.0464652220272697 ); ============================ group2718 ========================= ----------------C2-------------- REACTOME_PEPTIDE_CHAIN_ELONGATION ( 1.24550084736401e-05 ); REACTOME_VIRAL_MRNA_TRANSLATION ( 1.24550084736401e-05 ); KEGG_RIBOSOME ( 1.43163313085131e-05 ); REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS ( 1.94485909822394e-05 ); REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION ( 2.48277629472002e-05 ); REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS ( 2.48277629472002e-05 ); REACTOME_METABOLISM_OF_PROTEINS ( 2.96718624198364e-05 ); REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT ( 3.00846634633196e-05 ); REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT ( 3.87595112277041e-05 ); REACTOME_TRANSLATION ( 4.91387591632115e-05 ); REACTOME_INSULIN_SYNTHESIS_AND_SECRETION ( 6.53027758288106e-05 ); REACTOME_INFLUENZA_LIFE_CYCLE ( 8.26564415695514e-05 ); REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX ( 0.00304461586276548 ); REACTOME_DIABETES_PATHWAYS ( 0.0034468178478783 ); REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION ( 0.00397835228702289 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING ( 0.00412129674818568 ); REACTOME_GENE_EXPRESSION ( 0.00564438282187155 ); REACTOME_TELOMERE_MAINTENANCE ( 0.00727739946953276 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE ( 0.00804552612138348 ); ----------------C3-------------- V$E2F_Q6 ( 0.000178386791882608 ); V$E2F1_Q6_01 ( 0.000228062607995001 ); TTTNNANAGCYR_UNKNOWN ( 0.00103876832540644 ); SGCGSSAAA_V$E2F1DP2_01 ( 0.00117212891007358 ); V$E2F1DP1RB_01 ( 0.00282397496093916 ); V$E2F_02 ( 0.00287229381628203 ); V$E2F_Q4 ( 0.00287229381628203 ); V$E2F1_Q6 ( 0.00287229381628203 ); V$E2F1DP1_01 ( 0.00287229381628203 ); V$E2F1DP2_01 ( 0.00287229381628203 ); V$E2F4DP2_01 ( 0.00287229381628203 ); V$E2F1_Q4_01 ( 0.00287229381628203 ); V$E2F_Q3_01 ( 0.00307067540220314 ); V$E2F4DP1_01 ( 0.00312155621872756 ); KRCTCNNNNMANAGC_UNKNOWN ( 0.00456428334742094 ); GTGACGY_V$E4F1_Q6 ( 0.00750278045206499 ); ----------------C4-------------- GCM_TPT1 ( 5.68231090669385e-06 ); GCM_NPM1 ( 3.48441238214659e-05 ); GNF2_EIF3S6 ( 3.61154070796852e-05 ); MORF_NME2 ( 0.000105947175453494 ); MORF_NPM1 ( 0.00013036131465336 ); module_392 ( 0.000426436522707319 ); GCM_CSNK2B ( 0.000484119837136066 ); GNF2_DAP3 ( 0.000697727662541883 ); module_29 ( 0.00104232625390443 ); GNF2_FBL ( 0.00117212891007358 ); GNF2_GLTSCR2 ( 0.00127811635490502 ); MORF_ACTG1 ( 0.00153502016560133 ); MORF_EI24 ( 0.00160158731170202 ); module_83 ( 0.0016061249942766 ); module_151 ( 0.0016061249942766 ); module_114 ( 0.00196674903116521 ); module_98 ( 0.00386476179940797 ); MORF_RPA1 ( 0.00397835228702289 ); GNF2_ST13 ( 0.00426660541654777 ); GNF2_NPM1 ( 0.00441427028047649 ); MORF_JUND ( 0.00518765846003043 ); MORF_UBE2I ( 0.00545346382554601 ); MORF_UNG ( 0.00567945711548478 ); MORF_EIF3S2 ( 0.00628006370192136 ); module_252 ( 0.0066792446652947 ); module_32 ( 0.00700928427176594 ); module_54 ( 0.007966511988488 ); MORF_RAN ( 0.00833283410769198 ); MORF_SOD1 ( 0.00861402107458002 ); MORF_CSNK2B ( 0.00959154638380433 ); ----------------C5-------------- STRUCTURAL_CONSTITUENT_OF_RIBOSOME ( 0.000342541128182077 ); RNA_BINDING ( 0.000698823741985829 ); NUCLEOLUS ( 0.00103876832540644 ); NUCLEUS ( 0.00163132843742217 ); NUCLEAR_PART ( 0.00216809421993272 ); INTRACELLULAR_ORGANELLE_PART ( 0.00279497856573333 ); ORGANELLE_PART ( 0.00286433382963961 ); NUCLEAR_LUMEN ( 0.0034468178478783 ); NUCLEASE_ACTIVITY ( 0.00369958812846795 ); ORGANELLE_LUMEN ( 0.00632526265582647 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00632526265582647 ); STRUCTURAL_MOLECULE_ACTIVITY ( 0.00805717459672914 ); ----------------GOSLIM-------------- GO:0032991 macromolecular complex ( 6.33384030793542e-05 ); GO:0022626 cytosolic ribosome ( 0.000264568577883596 ); GO:0044446 intracellular organelle part ( 0.000310371577085403 ); GO:0044422 organelle part ( 0.000317140672953123 ); GO:0006414 translational elongation ( 0.000386077465726792 ); GO:0033279 ribosomal subunit ( 0.00137013811033203 ); GO:0030529 ribonucleoprotein complex ( 0.00219669388783244 ); GO:0044445 cytosolic part ( 0.00231157485785832 ); GO:0003735 structural constituent of ribosome ( 0.00243992968533022 ); GO:0044428 nuclear part ( 0.0050146265533714 ); GO:0005840 ribosome ( 0.00596349169472661 ); GO:0044424 intracellular part ( 6.33384030793542e-05 ); GO:0006364 rRNA processing ( 0.000264568577883596 ); GO:0016072 rRNA metabolic process ( 0.000310371577085403 ); GO:0043229 intracellular organelle ( 0.000317140672953123 ); GO:0043226 organelle ( 0.000386077465726792 ); GO:0005575 cellular_component ( 0.00137013811033203 ); GO:0005622 intracellular ( 0.00219669388783244 ); GO:0042254 ribosome biogenesis ( 0.00231157485785832 ); GO:0003676 nucleic acid binding ( 0.00243992968533022 ); GO:0022627 cytosolic small ribosomal subunit ( 0.0050146265533714 ); GO:0004518 nuclease activity ( 0.00596349169472661 ); GO:0004334 fumarylacetoacetase activity ( 6.33384030793542e-05 ); GO:0008995 ribonuclease E activity ( 0.000264568577883596 ); GO:0022625 cytosolic large ribosomal subunit ( 0.000310371577085403 ); GO:0005198 structural molecule activity ( 0.000317140672953123 ); GO:0034470 ncRNA processing ( 0.000386077465726792 ); GO:0031981 nuclear lumen ( 0.00137013811033203 ); GO:0044464 cell part ( 0.00219669388783244 ); GO:0005623 cell ( 0.00231157485785832 ); GO:0006412 translation ( 0.00243992968533022 ); GO:0004531 deoxyribonuclease II activity ( 0.0050146265533714 ); GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds ( 0.00596349169472661 ); GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances ( 6.33384030793542e-05 ); GO:0015935 small ribosomal subunit ( 0.000264568577883596 ); GO:0015934 large ribosomal subunit ( 0.000310371577085403 ); GO:0003723 RNA binding ( 0.000317140672953123 ); GO:0034660 ncRNA metabolic process ( 0.000386077465726792 ); GO:0006271 DNA strand elongation during DNA replication ( 0.00137013811033203 ); GO:0045618 positive regulation of keratinocyte differentiation ( 0.00219669388783244 ); GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters ( 0.00231157485785832 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.00243992968533022 ); GO:0006572 tyrosine catabolic process ( 0.0050146265533714 ); GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger ( 0.00596349169472661 ); GO:0005432 calcium:sodium antiporter activity ( 6.33384030793542e-05 ); GO:0005737 cytoplasm ( 0.000264568577883596 ); GO:0043228 non-membrane-bounded organelle ( 0.000310371577085403 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.000317140672953123 ); GO:0005634 nucleus ( 0.000386077465726792 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00137013811033203 ); GO:0043227 membrane-bounded organelle ( 0.00219669388783244 ); GO:0070013 intracellular organelle lumen ( 0.00231157485785832 ); GO:0021520 spinal cord motor neuron cell fate specification ( 0.00243992968533022 ); GO:0022616 DNA strand elongation ( 0.0050146265533714 ); GO:0045616 regulation of keratinocyte differentiation ( 0.00596349169472661 ); GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex ( 6.33384030793542e-05 ); GO:0032040 small-subunit processome ( 0.000264568577883596 ); GO:0003689 DNA clamp loader activity ( 0.000310371577085403 ); GO:0004865 protein serine/threonine phosphatase inhibitor activity ( 0.000317140672953123 ); GO:0033170 DNA-protein loading ATPase activity ( 0.000386077465726792 ); GO:0004519 endonuclease activity ( 0.00137013811033203 ); GO:0043233 organelle lumen ( 0.00219669388783244 ); GO:0016607 nuclear speck ( 0.00231157485785832 ); GO:0006396 RNA processing ( 0.00243992968533022 ); ----------------GO-------------- GO:0032991 macromolecular complex ( 5.47450148141957e-06 ); GO:0022626 cytosolic ribosome ( 7.11973379163319e-06 ); GO:0044446 intracellular organelle part ( 1.66380923700825e-05 ); GO:0044422 organelle part ( 1.77056816307956e-05 ); GO:0006414 translational elongation ( 2.38634225933672e-05 ); GO:0033279 ribosomal subunit ( 3.36059524763312e-05 ); GO:0030529 ribonucleoprotein complex ( 6.01253413279115e-05 ); GO:0044445 cytosolic part ( 6.73112403731858e-05 ); GO:0003735 structural constituent of ribosome ( 0.000100404539108383 ); GO:0044428 nuclear part ( 0.00011397168883527 ); GO:0005840 ribosome ( 0.000281248848734076 ); GO:0044424 intracellular part ( 0.000309405891704979 ); GO:0006364 rRNA processing ( 0.000330080531691204 ); GO:0016072 rRNA metabolic process ( 0.000368363903153765 ); GO:0043229 intracellular organelle ( 0.00055406355760724 ); GO:0043226 organelle ( 0.000557612855003262 ); GO:0005575 cellular_component ( 0.000643155787400132 ); GO:0005622 intracellular ( 0.00073102755098541 ); GO:0042254 ribosome biogenesis ( 0.000759112956384881 ); GO:0003676 nucleic acid binding ( 0.000774806189804844 ); GO:0022627 cytosolic small ribosomal subunit ( 0.00153704390721461 ); GO:0004518 nuclease activity ( 0.0017047939814116 ); GO:0004334 fumarylacetoacetase activity ( 0.0017091439199719 ); GO:0008995 ribonuclease E activity ( 0.0017091439199719 ); GO:0022625 cytosolic large ribosomal subunit ( 0.0018188799114458 ); GO:0005198 structural molecule activity ( 0.0019670397385881 ); GO:0034470 ncRNA processing ( 0.00228316673308309 ); GO:0031981 nuclear lumen ( 0.00254324322259024 ); GO:0044464 cell part ( 0.00293133067411294 ); GO:0005623 cell ( 0.0029365838819046 ); GO:0006412 translation ( 0.00315445834856358 ); GO:0004531 deoxyribonuclease II activity ( 0.00341545244132369 ); GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds ( 0.00341545244132369 ); GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances ( 0.00341545244132369 ); GO:0015935 small ribosomal subunit ( 0.00369958812846795 ); GO:0015934 large ribosomal subunit ( 0.00397835228702289 ); GO:0003723 RNA binding ( 0.00416022027061407 ); GO:0034660 ncRNA metabolic process ( 0.00437486597390013 ); GO:0006271 DNA strand elongation during DNA replication ( 0.00511893012555176 ); GO:0045618 positive regulation of keratinocyte differentiation ( 0.00511893012555176 ); GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters ( 0.00511893012555176 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.00574590477239357 ); GO:0006572 tyrosine catabolic process ( 0.00681958152704698 ); GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger ( 0.00681958152704698 ); GO:0005432 calcium:sodium antiporter activity ( 0.00681958152704698 ); GO:0005737 cytoplasm ( 0.00684952795144127 ); GO:0043228 non-membrane-bounded organelle ( 0.0071256683722787 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.0071256683722787 ); GO:0005634 nucleus ( 0.0073516872590343 ); GO:0043231 intracellular membrane-bounded organelle ( 0.0076296012721126 ); GO:0043227 membrane-bounded organelle ( 0.0076692035600548 ); GO:0070013 intracellular organelle lumen ( 0.00821013805077426 ); GO:0021520 spinal cord motor neuron cell fate specification ( 0.00851741119309768 ); GO:0022616 DNA strand elongation ( 0.00851741119309768 ); GO:0045616 regulation of keratinocyte differentiation ( 0.00851741119309768 ); GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex ( 0.00851741119309768 ); GO:0032040 small-subunit processome ( 0.00851741119309768 ); GO:0003689 DNA clamp loader activity ( 0.00851741119309768 ); GO:0004865 protein serine/threonine phosphatase inhibitor activity ( 0.00851741119309768 ); GO:0033170 DNA-protein loading ATPase activity ( 0.00851741119309768 ); GO:0004519 endonuclease activity ( 0.00864458721482829 ); GO:0043233 organelle lumen ( 0.00925814622032646 ); GO:0016607 nuclear speck ( 0.00926310647595364 ); GO:0006396 RNA processing ( 0.00952841182233403 ); ----------------KEGG-------------- hsa03010 Ribosome ( 6.73773674856097e-06 ); hsa00643 Styrene degradation ( 0.00511893012555176 ); hsa05322 Systemic lupus erythematosus ( 0.0195626046371065 ); hsa05060 Prion disease ( 0.0219990093861869 ); hsa03430 Mismatch repair ( 0.0386009701265666 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00014723810561389 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000282259369801915 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00325533081631307 ); TIAL1_iCLIP_(Wang_2010) ( 0.00667377809755647 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0124265996677445 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0187570884096084 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0303832777960087 ); TIA1_iCLIP_(Wang_2010) ( 0.0374568289078514 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2984 ========================= ----------------C2-------------- ( 0.00412129674818568 ); ----------------C3-------------- ( ); ----------------C4-------------- module_148 ( 0.000218567110210453 ); module_165 ( 0.00785019838493558 ); MORF_JAK3 ( 0.00905478391685257 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0006692 prostanoid metabolic process ( ); GO:0006693 prostaglandin metabolic process ( ); GO:0019371 cyclooxygenase pathway ( ); GO:0006690 icosanoid metabolic process ( ); GO:0006497 protein amino acid lipidation ( ); GO:0042158 lipoprotein biosynthetic process ( ); GO:0006427 histidyl-tRNA aminoacylation ( ); GO:0004666 prostaglandin-endoperoxide synthase activity ( ); GO:0004821 histidine-tRNA ligase activity ( ); GO:0004839 ubiquitin activating enzyme activity ( ); GO:0042157 lipoprotein metabolic process ( ); GO:0019369 arachidonic acid metabolic process ( ); GO:0045578 negative regulation of B cell differentiation ( ); GO:0003997 acyl-CoA oxidase activity ( ); GO:0031116 positive regulation of microtubule polymerization ( ); GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity ( ); ----------------GO-------------- GO:0006692 prostanoid metabolic process ( 0.000218567110210453 ); GO:0006693 prostaglandin metabolic process ( 0.000218567110210453 ); GO:0019371 cyclooxygenase pathway ( 0.0017091439199719 ); GO:0006690 icosanoid metabolic process ( 0.0018188799114458 ); GO:0006497 protein amino acid lipidation ( 0.00268071535201894 ); GO:0042158 lipoprotein biosynthetic process ( 0.00317078493677139 ); GO:0006427 histidyl-tRNA aminoacylation ( 0.00341545244132369 ); GO:0004666 prostaglandin-endoperoxide synthase activity ( 0.00341545244132369 ); GO:0004821 histidine-tRNA ligase activity ( 0.00341545244132369 ); GO:0004839 ubiquitin activating enzyme activity ( 0.00341545244132369 ); GO:0042157 lipoprotein metabolic process ( 0.00672453757118312 ); GO:0019369 arachidonic acid metabolic process ( 0.00681958152704698 ); GO:0045578 negative regulation of B cell differentiation ( 0.00681958152704698 ); GO:0003997 acyl-CoA oxidase activity ( 0.00681958152704698 ); GO:0031116 positive regulation of microtubule polymerization ( 0.00851741119309768 ); GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity ( 0.00851741119309768 ); ----------------KEGG-------------- hsa00592 alpha-Linolenic acid metabolism ( 0.0270085964315093 ); hsa01040 Biosynthesis of unsaturated fatty acids ( 0.0353026130688544 ); hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis ( 0.0386009701265666 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0187570884096084 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2973 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ATCMNTCCGY_UNKNOWN ( 0.00162292875898878 ); TTAYRTAA_V$E4BP4_01 ( 0.00346341377039249 ); ----------------C4-------------- ( 0.000841367662632043 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0008095 inositol-1,4,5-triphosphate receptor activity ( 0.000136294665880838 ); GO:0004869 cysteine-type endopeptidase inhibitor activity ( 0.004795641266763 ); GO:0000822 inositol hexakisphosphate binding ( 0.000136294665880838 ); GO:0004092 carnitine O-acetyltransferase activity ( 0.004795641266763 ); GO:0030729 acetoacetate-CoA ligase activity ( 0.000136294665880838 ); GO:0031929 TOR signaling pathway ( 0.004795641266763 ); GO:0048630 skeletal muscle growth ( 0.000136294665880838 ); GO:0050916 sensory perception of sweet taste ( 0.004795641266763 ); GO:0070050 neuron maintenance ( 0.000136294665880838 ); GO:0005220 inositol 1,4,5-triphosphate-sensitive calcium-release channel activity ( 0.004795641266763 ); GO:0016413 O-acetyltransferase activity ( 0.000136294665880838 ); GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding ( 0.004795641266763 ); GO:0016407 acetyltransferase activity ( 0.000136294665880838 ); GO:0050917 sensory perception of umami taste ( 0.004795641266763 ); GO:0017150 tRNA dihydrouridine synthase activity ( 0.000136294665880838 ); GO:0043178 alcohol binding ( 0.004795641266763 ); GO:0035091 phosphoinositide binding ( 0.000136294665880838 ); GO:0016406 carnitine O-acyltransferase activity ( 0.004795641266763 ); ----------------GO-------------- GO:0008095 inositol-1,4,5-triphosphate receptor activity ( 1.59784095144616e-05 ); GO:0004869 cysteine-type endopeptidase inhibitor activity ( 0.00136440464169385 ); GO:0000822 inositol hexakisphosphate binding ( 0.00165887498114958 ); GO:0004092 carnitine O-acetyltransferase activity ( 0.00165887498114958 ); GO:0030729 acetoacetate-CoA ligase activity ( 0.00165887498114958 ); GO:0031929 TOR signaling pathway ( 0.00331508135183189 ); GO:0048630 skeletal muscle growth ( 0.00496862327106151 ); GO:0050916 sensory perception of sweet taste ( 0.00496862327106151 ); GO:0070050 neuron maintenance ( 0.00496862327106151 ); GO:0005220 inositol 1,4,5-triphosphate-sensitive calcium-release channel activity ( 0.00496862327106151 ); GO:0016413 O-acetyltransferase activity ( 0.00496862327106151 ); GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding ( 0.00496862327106151 ); GO:0016407 acetyltransferase activity ( 0.00535677866752772 ); GO:0050917 sensory perception of umami taste ( 0.00661950489157725 ); GO:0017150 tRNA dihydrouridine synthase activity ( 0.00661950489157725 ); GO:0043178 alcohol binding ( 0.00661950489157725 ); GO:0035091 phosphoinositide binding ( 0.00815775054943567 ); GO:0016406 carnitine O-acyltransferase activity ( 0.00991330381611566 ); ----------------KEGG-------------- hsa04710 Circadian rhythm ( 0.0213584081427759 ); hsa00252 Alanine and aspartate metabolism ( 0.0454532620959657 ); ----------------CARTA-------------- tertpathway ( 0.00496862327106151 ); vdrpathway ( 0.00496862327106151 ); mcalpainpathway ( 0.0213584081427759 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0308751802115013 ); TIA1_iCLIP_(Wang_2010) ( 0.0334149572970108 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2995 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00316992363824272 ); ----------------C4-------------- ( ); ----------------C5-------------- INTEGRAL_TO_MEMBRANE ( 0.00378961529206443 ); INTRINSIC_TO_MEMBRANE ( 0.00409241266148884 ); DEFENSE_RESPONSE ( 0.00818848566451082 ); ----------------GOSLIM-------------- GO:0006879 cellular iron ion homeostasis ( ); GO:0055072 iron ion homeostasis ( ); GO:0006826 iron ion transport ( ); GO:0042581 specific granule ( ); GO:0016403 dimethylargininase activity ( ); GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity ( ); GO:0004995 tachykinin receptor activity ( ); GO:0000041 transition metal ion transport ( ); GO:0030815 negative regulation of cAMP metabolic process ( ); GO:0030818 negative regulation of cAMP biosynthetic process ( ); GO:0030800 negative regulation of cyclic nucleotide metabolic process ( ); GO:0030803 negative regulation of cyclic nucleotide biosynthetic process ( ); GO:0030809 negative regulation of nucleotide biosynthetic process ( ); ----------------GO-------------- GO:0006879 cellular iron ion homeostasis ( 0.00051648516635586 ); GO:0055072 iron ion homeostasis ( 0.000734878279298592 ); GO:0006826 iron ion transport ( 0.00079531928671225 ); GO:0042581 specific granule ( 0.00321470520815392 ); GO:0016403 dimethylargininase activity ( 0.00321470520815392 ); GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity ( 0.00321470520815392 ); GO:0004995 tachykinin receptor activity ( 0.00481830127840388 ); GO:0000041 transition metal ion transport ( 0.00504286675504207 ); GO:0030815 negative regulation of cAMP metabolic process ( 0.00641939802848401 ); GO:0030818 negative regulation of cAMP biosynthetic process ( 0.00641939802848401 ); GO:0030800 negative regulation of cyclic nucleotide metabolic process ( 0.0080179992282976 ); GO:0030803 negative regulation of cyclic nucleotide biosynthetic process ( 0.0080179992282976 ); GO:0030809 negative regulation of nucleotide biosynthetic process ( 0.0080179992282976 ); ----------------KEGG-------------- hsa00030 Pentose phosphate pathway ( 0.0410187707263026 ); hsa05216 Thyroid cancer ( 0.0456454688390616 ); ----------------CARTA-------------- tcrapathway ( 0.00641939802848401 ); mef2dpathway ( 0.0379222414368067 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0124114481582742 ); ----------------ARE-------------- ( ); ============================ group2972 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$ETS_Q4 ( 0.00231873570253963 ); AACTGGA,MIR-145 ( 0.00283721704628957 ); CAAGGAT,MIR-362 ( 0.00299654242202855 ); GTACTGT,MIR-101 ( 0.00440170423142528 ); TCTGATA,MIR-361 ( 0.00555125171445166 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005731 nucleolus organizer region ( 0.00697490105572735 ); GO:0016442 RNA-induced silencing complex ( 0.00726235266629702 ); GO:0030874 nucleolar chromatin ( 0.00697490105572735 ); GO:0031332 RNAi effector complex ( 0.00726235266629702 ); GO:0015382 sodium:sulfate symporter activity ( 0.00697490105572735 ); GO:0016034 maleylacetoacetate isomerase activity ( 0.00726235266629702 ); GO:0000354 cis assembly of pre-catalytic spliceosome ( 0.00697490105572735 ); GO:0003920 GMP reductase activity ( 0.00726235266629702 ); GO:0004373 glycogen (starch) synthase activity ( 0.00697490105572735 ); GO:0016657 oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor ( 0.00726235266629702 ); GO:0016246 RNA interference ( 0.00697490105572735 ); GO:0016973 poly(A)+ mRNA export from nucleus ( 0.00726235266629702 ); GO:0045292 nuclear mRNA cis splicing, via spliceosome ( 0.00697490105572735 ); GO:0015698 inorganic anion transport ( 0.00726235266629702 ); GO:0006572 tyrosine catabolic process ( 0.00697490105572735 ); GO:0005682 snRNP U5 ( 0.00726235266629702 ); GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity ( 0.00697490105572735 ); GO:0002011 morphogenesis of an epithelial sheet ( 0.00726235266629702 ); GO:0015081 sodium ion transmembrane transporter activity ( 0.00697490105572735 ); GO:0034637 cellular carbohydrate biosynthetic process ( 0.00726235266629702 ); GO:0035251 UDP-glucosyltransferase activity ( 0.00697490105572735 ); ----------------GO-------------- GO:0005731 nucleolus organizer region ( 0.00150806816468096 ); GO:0016442 RNA-induced silencing complex ( 0.00150806816468096 ); GO:0030874 nucleolar chromatin ( 0.00150806816468096 ); GO:0031332 RNAi effector complex ( 0.00150806816468096 ); GO:0015382 sodium:sulfate symporter activity ( 0.00150806816468096 ); GO:0016034 maleylacetoacetate isomerase activity ( 0.00150806816468096 ); GO:0000354 cis assembly of pre-catalytic spliceosome ( 0.00301393775823899 ); GO:0003920 GMP reductase activity ( 0.00301393775823899 ); GO:0004373 glycogen (starch) synthase activity ( 0.00301393775823899 ); GO:0016657 oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor ( 0.00301393775823899 ); GO:0016246 RNA interference ( 0.00451761187554089 ); GO:0016973 poly(A)+ mRNA export from nucleus ( 0.00451761187554089 ); GO:0045292 nuclear mRNA cis splicing, via spliceosome ( 0.00451761187554089 ); GO:0015698 inorganic anion transport ( 0.00599687018830848 ); GO:0006572 tyrosine catabolic process ( 0.00601909360725195 ); GO:0005682 snRNP U5 ( 0.00601909360725195 ); GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity ( 0.00601909360725195 ); GO:0002011 morphogenesis of an epithelial sheet ( 0.00751838603984234 ); GO:0015081 sodium ion transmembrane transporter activity ( 0.00751838603984234 ); GO:0034637 cellular carbohydrate biosynthetic process ( 0.00759603336057414 ); GO:0035251 UDP-glucosyltransferase activity ( 0.00901549225559073 ); ----------------KEGG-------------- hsa00643 Styrene degradation ( 0.00451761187554089 ); hsa04650 Natural killer cell mediated cytotoxicity ( 0.0165958367824993 ); hsa00534 Heparan sulfate biosynthesis ( 0.0282803221725775 ); hsa00790 Folate biosynthesis ( 0.0486221188574546 ); ----------------CARTA-------------- fibrinolysispathway ( 0.0268113581849319 ); rac1pathway ( 0.0297471426583787 ); ----------------RBP-------------- ( 0.0106392949641313 ); ----------------immu-------------- ( 0.0165958367824993 ); ----------------ARE-------------- ( ); ============================ group22 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$E2F_Q6 ( 0.00177779752533607 ); V$E2F_Q4 ( 0.00180855125680317 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0003968 RNA-directed RNA polymerase activity ( ); GO:0006685 sphingomyelin catabolic process ( ); ----------------GO-------------- GO:0003968 RNA-directed RNA polymerase activity ( 0.00145779922585865 ); GO:0006685 sphingomyelin catabolic process ( 0.00726850396774414 ); ----------------KEGG-------------- hsa00040 Pentose and glucuronate interconversions ( 0.0245054002993803 ); hsa03020 RNA polymerase ( 0.0358357412891984 ); hsa00860 Porphyrin and chlorophyll metabolism ( 0.0470389677265131 ); ----------------CARTA-------------- pmlpathway ( 0.0144859857535541 ); ghpathway ( 0.0442500026259999 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2985 ========================= ----------------C2-------------- REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION ( 0.000383581918991837 ); REACTOME_TRNA_AMINOACYLATION ( 0.00154650698756394 ); KEGG_AMINOACYL_TRNA_BIOSYNTHESIS ( 0.00162434804824497 ); REACTOME_GENE_EXPRESSION ( 0.00314196464563336 ); ----------------C3-------------- ( ); ----------------C4-------------- GCM_TPT1 ( 0.000136796292789226 ); GCM_NPM1 ( 0.000527077303578963 ); GNF2_EIF3S6 ( 0.000541325432974685 ); MORF_PSMF1 ( 0.00138132825252637 ); GCM_CRKL ( 0.0024069899848909 ); MORF_ATRX ( 0.00245736301990514 ); MORF_REV3L ( 0.00270030162433126 ); GNF2_ST13 ( 0.00311623016808761 ); MORF_JAG1 ( 0.00710970911536872 ); GCM_CSNK2B ( 0.00759092882232301 ); module_83 ( 0.00911678217457177 ); module_151 ( 0.00911678217457177 ); MORF_TPT1 ( 0.00929809253453055 ); GNF2_DAP3 ( 0.00965828110890967 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005759 mitochondrial matrix ( 0.00183621645059088 ); GO:0031980 mitochondrial lumen ( 0.00215370176496956 ); GO:0044429 mitochondrial part ( 0.00183621645059088 ); GO:0006520 amino acid metabolic process ( 0.00215370176496956 ); GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain ( 0.00183621645059088 ); GO:0006519 cellular amino acid and derivative metabolic process ( 0.00215370176496956 ); GO:0055085 transmembrane transport ( 0.00183621645059088 ); GO:0009308 cellular amine metabolic process ( 0.00215370176496956 ); GO:0015985 energy coupled proton transport, down electrochemical gradient ( 0.00183621645059088 ); GO:0015986 ATP synthesis coupled proton transport ( 0.00215370176496956 ); GO:0034220 transmembrane ion transport ( 0.00183621645059088 ); GO:0014889 muscle atrophy ( 0.00215370176496956 ); GO:0048936 peripheral nervous system neuron axonogenesis ( 0.00183621645059088 ); GO:0070189 kynurenine metabolic process ( 0.00215370176496956 ); GO:0004502 kynurenine 3-monooxygenase activity ( 0.00183621645059088 ); GO:0034722 gamma-glutamyl-peptidase activity ( 0.00215370176496956 ); GO:0034641 cellular nitrogen compound metabolic process ( 0.00183621645059088 ); GO:0016469 proton-transporting two-sector ATPase complex ( 0.00215370176496956 ); GO:0006807 nitrogen compound metabolic process ( 0.00183621645059088 ); GO:0006418 tRNA aminoacylation for protein translation ( 0.00215370176496956 ); GO:0043038 amino acid activation ( 0.00183621645059088 ); GO:0043039 tRNA aminoacylation ( 0.00215370176496956 ); GO:0004812 aminoacyl-tRNA ligase activity ( 0.00183621645059088 ); GO:0016875 ligase activity, forming carbon-oxygen bonds ( 0.00215370176496956 ); GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds ( 0.00183621645059088 ); GO:0030554 adenyl nucleotide binding ( 0.00215370176496956 ); GO:0005739 mitochondrion ( 0.00183621645059088 ); GO:0006421 asparaginyl-tRNA aminoacylation ( 0.00215370176496956 ); GO:0006437 tyrosyl-tRNA aminoacylation ( 0.00183621645059088 ); GO:0004658 propionyl-CoA carboxylase activity ( 0.00215370176496956 ); GO:0004831 tyrosine-tRNA ligase activity ( 0.00183621645059088 ); GO:0015992 proton transport ( 0.00215370176496956 ); GO:0006818 hydrogen transport ( 0.00183621645059088 ); GO:0048935 peripheral nervous system neuron development ( 0.00215370176496956 ); GO:0008242 omega peptidase activity ( 0.00183621645059088 ); GO:0016527 brain-specific angiogenesis inhibitor activity ( 0.00215370176496956 ); GO:0019752 carboxylic acid metabolic process ( 0.00183621645059088 ); GO:0006082 organic acid metabolic process ( 0.00215370176496956 ); GO:0009165 nucleotide biosynthetic process ( 0.00183621645059088 ); GO:0048934 peripheral nervous system neuron differentiation ( 0.00215370176496956 ); GO:0000931 gamma-tubulin large complex ( 0.00183621645059088 ); GO:0008274 gamma-tubulin ring complex ( 0.00215370176496956 ); GO:0004815 aspartate-tRNA ligase activity ( 0.00183621645059088 ); GO:0006119 oxidative phosphorylation ( 0.00215370176496956 ); GO:0006754 ATP biosynthetic process ( 0.00183621645059088 ); GO:0015078 hydrogen ion transmembrane transporter activity ( 0.00215370176496956 ); GO:0007025 beta-tubulin folding ( 0.00183621645059088 ); GO:0009374 biotin binding ( 0.00215370176496956 ); GO:0016174 NAD(P)H oxidase activity ( 0.00183621645059088 ); GO:0005524 ATP binding ( 0.00215370176496956 ); GO:0017076 purine nucleotide binding ( 0.00183621645059088 ); GO:0046034 ATP metabolic process ( 0.00215370176496956 ); GO:0032559 adenyl ribonucleotide binding ( 0.00183621645059088 ); GO:0009145 purine nucleoside triphosphate biosynthetic process ( 0.00215370176496956 ); GO:0009206 purine ribonucleoside triphosphate biosynthetic process ( 0.00183621645059088 ); GO:0009142 nucleoside triphosphate biosynthetic process ( 0.00215370176496956 ); GO:0009201 ribonucleoside triphosphate biosynthetic process ( 0.00183621645059088 ); GO:0009651 response to salt stress ( 0.00215370176496956 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00183621645059088 ); GO:0016421 CoA carboxylase activity ( 0.00215370176496956 ); GO:0015077 monovalent inorganic cation transmembrane transporter activity ( 0.00183621645059088 ); ----------------GO-------------- GO:0005759 mitochondrial matrix ( 6.70201938013269e-06 ); GO:0031980 mitochondrial lumen ( 6.70201938013269e-06 ); GO:0044429 mitochondrial part ( 8.01336343052074e-05 ); GO:0006520 amino acid metabolic process ( 0.000241614276576384 ); GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain ( 0.000423575832927053 ); GO:0006519 cellular amino acid and derivative metabolic process ( 0.000700675529005251 ); GO:0055085 transmembrane transport ( 0.000767284270169374 ); GO:0009308 cellular amine metabolic process ( 0.00121675579587714 ); GO:0015985 energy coupled proton transport, down electrochemical gradient ( 0.00132406050314066 ); GO:0015986 ATP synthesis coupled proton transport ( 0.00132406050314066 ); GO:0034220 transmembrane ion transport ( 0.00139635804155678 ); GO:0014889 muscle atrophy ( 0.00145779922585865 ); GO:0048936 peripheral nervous system neuron axonogenesis ( 0.00145779922585865 ); GO:0070189 kynurenine metabolic process ( 0.00145779922585865 ); GO:0004502 kynurenine 3-monooxygenase activity ( 0.00145779922585865 ); GO:0034722 gamma-glutamyl-peptidase activity ( 0.00145779922585865 ); GO:0034641 cellular nitrogen compound metabolic process ( 0.00161342059786274 ); GO:0016469 proton-transporting two-sector ATPase complex ( 0.00170402661985999 ); GO:0006807 nitrogen compound metabolic process ( 0.00180562496413696 ); GO:0006418 tRNA aminoacylation for protein translation ( 0.00195403597287766 ); GO:0043038 amino acid activation ( 0.00195403597287766 ); GO:0043039 tRNA aminoacylation ( 0.00195403597287766 ); GO:0004812 aminoacyl-tRNA ligase activity ( 0.0021298023243431 ); GO:0016875 ligase activity, forming carbon-oxygen bonds ( 0.0021298023243431 ); GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds ( 0.0021298023243431 ); GO:0030554 adenyl nucleotide binding ( 0.00240611886940494 ); GO:0005739 mitochondrion ( 0.0024068460861716 ); GO:0006421 asparaginyl-tRNA aminoacylation ( 0.00291354645200204 ); GO:0006437 tyrosyl-tRNA aminoacylation ( 0.00291354645200204 ); GO:0004658 propionyl-CoA carboxylase activity ( 0.00291354645200204 ); GO:0004831 tyrosine-tRNA ligase activity ( 0.00291354645200204 ); GO:0015992 proton transport ( 0.00322461571068152 ); GO:0006818 hydrogen transport ( 0.00344663594339593 ); GO:0048935 peripheral nervous system neuron development ( 0.00436724446381076 ); GO:0008242 omega peptidase activity ( 0.00436724446381076 ); GO:0016527 brain-specific angiogenesis inhibitor activity ( 0.00436724446381076 ); GO:0019752 carboxylic acid metabolic process ( 0.00485589887164624 ); GO:0006082 organic acid metabolic process ( 0.00500088649568135 ); GO:0009165 nucleotide biosynthetic process ( 0.00556720984933401 ); GO:0048934 peripheral nervous system neuron differentiation ( 0.0058188960430241 ); GO:0000931 gamma-tubulin large complex ( 0.0058188960430241 ); GO:0008274 gamma-tubulin ring complex ( 0.0058188960430241 ); GO:0004815 aspartate-tRNA ligase activity ( 0.0058188960430241 ); GO:0006119 oxidative phosphorylation ( 0.00664298866288632 ); GO:0006754 ATP biosynthetic process ( 0.00679694327708954 ); GO:0015078 hydrogen ion transmembrane transporter activity ( 0.00695251833274412 ); GO:0007025 beta-tubulin folding ( 0.00726850396774414 ); GO:0009374 biotin binding ( 0.00726850396774414 ); GO:0016174 NAD(P)H oxidase activity ( 0.00726850396774414 ); GO:0005524 ATP binding ( 0.00773265699426539 ); GO:0017076 purine nucleotide binding ( 0.00807958218867004 ); GO:0046034 ATP metabolic process ( 0.00825489091879618 ); GO:0032559 adenyl ribonucleotide binding ( 0.00831585527485629 ); GO:0009145 purine nucleoside triphosphate biosynthetic process ( 0.00842483892983593 ); GO:0009206 purine ribonucleoside triphosphate biosynthetic process ( 0.00842483892983593 ); GO:0009142 nucleoside triphosphate biosynthetic process ( 0.00859636066209523 ); GO:0009201 ribonucleoside triphosphate biosynthetic process ( 0.00859636066209523 ); GO:0009651 response to salt stress ( 0.00871607101244076 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00871607101244076 ); GO:0016421 CoA carboxylase activity ( 0.00871607101244076 ); GO:0015077 monovalent inorganic cation transmembrane transporter activity ( 0.00876945149515054 ); ----------------KEGG-------------- hsa00970 Aminoacyl-tRNA biosynthesis ( 0.00162434804824497 ); hsa00190 Oxidative phosphorylation ( 0.0119476357887272 ); hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis ( 0.0130465545567197 ); hsa00252 Alanine and aspartate metabolism ( 0.0400517732344084 ); hsa00790 Folate biosynthesis ( 0.0470389677265131 ); hsa00640 Propanoate metabolism ( 0.0498200742195271 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.000773498114038354 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0442500026259999 ); ============================ group26 ========================= ----------------C2-------------- ( ); ----------------C3-------------- CCTNTMAGA_UNKNOWN ( 0.000288379051406916 ); V$E4BP4_01 ( 0.00134193344977428 ); V$LBP1_Q6 ( 0.00149543179350707 ); V$AP4_Q6 ( 0.00163145218249268 ); V$MYOD_01 ( 0.00215115919933237 ); TTAYRTAA_V$E4BP4_01 ( 0.00215115919933237 ); V$SF1_Q6 ( 0.00221829468230734 ); CTGYNNCTYTAA_UNKNOWN ( 0.00311068096865453 ); ATCTTGC,MIR-31 ( 0.00311068096865453 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0007043 cell-cell junction assembly ( ); GO:0034329 cell junction assembly ( ); GO:0045216 cell-cell junction organization ( ); GO:0034330 cell junction organization ( ); GO:0006123 mitochondrial electron transport, cytochrome c to oxygen ( ); GO:0006784 heme a biosynthetic process ( ); GO:0043297 apical junction assembly ( ); GO:0046160 heme a metabolic process ( ); GO:0004045 aminoacyl-tRNA hydrolase activity ( ); GO:0004145 diamine N-acetyltransferase activity ( ); GO:0017162 aryl hydrocarbon receptor binding ( ); GO:0005737 cytoplasm ( ); GO:0032352 positive regulation of hormone metabolic process ( ); GO:0042789 mRNA transcription from RNA polymerase II promoter ( ); GO:0046886 positive regulation of hormone biosynthetic process ( ); GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ( ); GO:0005954 calcium- and calmodulin-dependent protein kinase complex ( ); GO:0035253 ciliary rootlet ( ); GO:0004091 carboxylesterase activity ( ); GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress ( ); GO:0043620 regulation of transcription in response to stress ( ); GO:0046885 regulation of hormone biosynthetic process ( ); GO:0016298 lipase activity ( ); GO:0045821 positive regulation of glycolysis ( ); GO:0009103 lipopolysaccharide biosynthetic process ( ); GO:0010575 positive regulation vascular endothelial growth factor production ( ); GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway ( ); GO:0045648 positive regulation of erythrocyte differentiation ( ); GO:0016494 C-X-C chemokine receptor activity ( ); GO:0017166 vinculin binding ( ); ----------------GO-------------- GO:0007043 cell-cell junction assembly ( 0.000147595928068239 ); GO:0034329 cell junction assembly ( 0.000256451694095927 ); GO:0045216 cell-cell junction organization ( 0.000321889183140706 ); GO:0034330 cell junction organization ( 0.000474589731509737 ); GO:0006123 mitochondrial electron transport, cytochrome c to oxygen ( 0.00281315009157812 ); GO:0006784 heme a biosynthetic process ( 0.00281315009157812 ); GO:0043297 apical junction assembly ( 0.00281315009157812 ); GO:0046160 heme a metabolic process ( 0.00281315009157812 ); GO:0004045 aminoacyl-tRNA hydrolase activity ( 0.00281315009157812 ); GO:0004145 diamine N-acetyltransferase activity ( 0.00281315009157812 ); GO:0017162 aryl hydrocarbon receptor binding ( 0.00281315009157812 ); GO:0005737 cytoplasm ( 0.00327290262893657 ); GO:0032352 positive regulation of hormone metabolic process ( 0.00421686191086512 ); GO:0042789 mRNA transcription from RNA polymerase II promoter ( 0.00421686191086512 ); GO:0046886 positive regulation of hormone biosynthetic process ( 0.00421686191086512 ); GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ( 0.00561866823899482 ); GO:0005954 calcium- and calmodulin-dependent protein kinase complex ( 0.00561866823899482 ); GO:0035253 ciliary rootlet ( 0.00561866823899482 ); GO:0004091 carboxylesterase activity ( 0.00634569699408011 ); GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress ( 0.0070185715669302 ); GO:0043620 regulation of transcription in response to stress ( 0.0070185715669302 ); GO:0046885 regulation of hormone biosynthetic process ( 0.0070185715669302 ); GO:0016298 lipase activity ( 0.00739565490286539 ); GO:0045821 positive regulation of glycolysis ( 0.00841657438250343 ); GO:0009103 lipopolysaccharide biosynthetic process ( 0.00981267917042006 ); GO:0010575 positive regulation vascular endothelial growth factor production ( 0.00981267917042006 ); GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway ( 0.00981267917042006 ); GO:0045648 positive regulation of erythrocyte differentiation ( 0.00981267917042006 ); GO:0016494 C-X-C chemokine receptor activity ( 0.00981267917042006 ); GO:0017166 vinculin binding ( 0.00981267917042006 ); ----------------KEGG-------------- hsa04530 Tight junction ( 0.0147560322941403 ); hsa00220 Urea cycle and metabolism of amino groups ( 0.0400517732344082 ); hsa00860 Porphyrin and chlorophyll metabolism ( 0.0454532620959651 ); ----------------CARTA-------------- cftrpathway ( 0.00281315009157812 ); cskpathway ( 0.00281315009157812 ); chrebppathway ( 0.00281315009157812 ); raccpathway ( 0.0139896301684388 ); fibrinolysispathway ( 0.0250452695183732 ); igf1mtorpathway ( 0.0359813267923259 ); il1rpathway ( 0.0373399880320612 ); gleevecpathway ( 0.0454532620959651 ); ----------------RBP-------------- ( 0.0216619354483928 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2722 ========================= ----------------C2-------------- ( 0.00851875975774888 ); ----------------C3-------------- CGTCTTA,MIR-208 ( 0.00841657438250343 ); GGCACTT,MIR-519E ( 0.00989004071473459 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005858 axonemal dynein complex ( ); GO:0044447 axoneme part ( ); GO:0005930 axoneme ( ); GO:0030286 dynein complex ( ); GO:0002536 respiratory burst during acute inflammatory response ( ); GO:0002679 respiratory burst during defense response ( ); GO:0015920 lipopolysaccharide transport ( ); GO:0034123 positive regulation of toll-like receptor signaling pathway ( ); GO:0034142 toll-like receptor 4 signaling pathway ( ); GO:0034143 regulation of toll-like receptor 4 signaling pathway ( ); GO:0034145 positive regulation of toll-like receptor 4 signaling pathway ( ); GO:0060264 regulation of respiratory burst during acute inflammatory response ( ); GO:0060265 positive regulation of respiratory burst during acute inflammatory response ( ); GO:0031433 telethonin binding ( ); GO:0051636 Gram-negative bacterial cell surface binding ( ); GO:0002275 myeloid cell activation during immune response ( ); GO:0002281 macrophage activation during immune response ( ); GO:0002532 production of molecular mediator of acute inflammatory response ( ); GO:0006710 androgen catabolic process ( ); GO:0030241 muscle thick filament assembly ( ); GO:0031033 myosin filament assembly or disassembly ( ); GO:0031034 myosin filament assembly ( ); GO:0032490 detection of molecule of bacterial origin ( ); GO:0034121 regulation of toll-like receptor signaling pathway ( ); GO:0060267 positive regulation of respiratory burst ( ); GO:0004944 C5a anaphylatoxin receptor activity ( ); GO:0008368 Gram-negative bacterial binding ( ); GO:0042805 actinin binding ( ); GO:0051393 alpha-actinin binding ( ); GO:0051637 Gram-positive bacterial cell surface binding ( ); GO:0044463 cell projection part ( ); GO:0006702 androgen biosynthetic process ( ); GO:0032757 positive regulation of interleukin-8 production ( ); GO:0004942 anaphylatoxin receptor activity ( ); GO:0051076 Gram-positive bacterial binding ( ); GO:0051635 bacterial cell surface binding ( ); GO:0003777 microtubule motor activity ( ); GO:0014866 skeletal myofibril assembly ( ); GO:0030240 muscle thin filament assembly ( ); GO:0043032 positive regulation of macrophage activation ( ); GO:0048739 cardiac muscle fiber development ( ); GO:0035085 cilium axoneme ( ); GO:0050327 testosterone 17-beta-dehydrogenase activity ( ); GO:0055003 cardiac myofibril assembly ( ); GO:0042056 chemoattractant activity ( ); GO:0002221 pattern recognition receptor signaling pathway ( ); GO:0002224 toll-like receptor signaling pathway ( ); GO:0008228 opsonization ( ); GO:0060263 regulation of respiratory burst ( ); GO:0002218 activation of innate immune response ( ); GO:0002758 innate immune response-activating signal transduction ( ); GO:0032720 negative regulation of tumor necrosis factor production ( ); GO:0032755 positive regulation of interleukin-6 production ( ); GO:0032760 positive regulation of tumor necrosis factor production ( ); GO:0005875 microtubule associated complex ( ); ----------------GO-------------- GO:0005858 axonemal dynein complex ( 6.83590184627826e-05 ); GO:0044447 axoneme part ( 0.000104255549274723 ); GO:0005930 axoneme ( 0.000226478065410161 ); GO:0030286 dynein complex ( 0.000757627943604901 ); GO:0002536 respiratory burst during acute inflammatory response ( 0.00140753028703566 ); GO:0002679 respiratory burst during defense response ( 0.00140753028703566 ); GO:0015920 lipopolysaccharide transport ( 0.00140753028703566 ); GO:0034123 positive regulation of toll-like receptor signaling pathway ( 0.00140753028703566 ); GO:0034142 toll-like receptor 4 signaling pathway ( 0.00140753028703566 ); GO:0034143 regulation of toll-like receptor 4 signaling pathway ( 0.00140753028703566 ); GO:0034145 positive regulation of toll-like receptor 4 signaling pathway ( 0.00140753028703566 ); GO:0060264 regulation of respiratory burst during acute inflammatory response ( 0.00140753028703566 ); GO:0060265 positive regulation of respiratory burst during acute inflammatory response ( 0.00140753028703566 ); GO:0031433 telethonin binding ( 0.00140753028703566 ); GO:0051636 Gram-negative bacterial cell surface binding ( 0.00140753028703566 ); GO:0002275 myeloid cell activation during immune response ( 0.00281315009157812 ); GO:0002281 macrophage activation during immune response ( 0.00281315009157812 ); GO:0002532 production of molecular mediator of acute inflammatory response ( 0.00281315009157812 ); GO:0006710 androgen catabolic process ( 0.00281315009157812 ); GO:0030241 muscle thick filament assembly ( 0.00281315009157812 ); GO:0031033 myosin filament assembly or disassembly ( 0.00281315009157812 ); GO:0031034 myosin filament assembly ( 0.00281315009157812 ); GO:0032490 detection of molecule of bacterial origin ( 0.00281315009157812 ); GO:0034121 regulation of toll-like receptor signaling pathway ( 0.00281315009157812 ); GO:0060267 positive regulation of respiratory burst ( 0.00281315009157812 ); GO:0004944 C5a anaphylatoxin receptor activity ( 0.00281315009157812 ); GO:0008368 Gram-negative bacterial binding ( 0.00281315009157812 ); GO:0042805 actinin binding ( 0.00281315009157812 ); GO:0051393 alpha-actinin binding ( 0.00281315009157812 ); GO:0051637 Gram-positive bacterial cell surface binding ( 0.00281315009157812 ); GO:0044463 cell projection part ( 0.00410928908059996 ); GO:0006702 androgen biosynthetic process ( 0.00421686191086512 ); GO:0032757 positive regulation of interleukin-8 production ( 0.00421686191086512 ); GO:0004942 anaphylatoxin receptor activity ( 0.00421686191086512 ); GO:0051076 Gram-positive bacterial binding ( 0.00421686191086512 ); GO:0051635 bacterial cell surface binding ( 0.00421686191086512 ); GO:0003777 microtubule motor activity ( 0.00459480173190686 ); GO:0014866 skeletal myofibril assembly ( 0.00561866823899482 ); GO:0030240 muscle thin filament assembly ( 0.00561866823899482 ); GO:0043032 positive regulation of macrophage activation ( 0.00561866823899482 ); GO:0048739 cardiac muscle fiber development ( 0.00561866823899482 ); GO:0035085 cilium axoneme ( 0.00561866823899482 ); GO:0050327 testosterone 17-beta-dehydrogenase activity ( 0.00561866823899482 ); GO:0055003 cardiac myofibril assembly ( 0.0070185715669302 ); GO:0042056 chemoattractant activity ( 0.0070185715669302 ); GO:0002221 pattern recognition receptor signaling pathway ( 0.00841657438250343 ); GO:0002224 toll-like receptor signaling pathway ( 0.00841657438250343 ); GO:0008228 opsonization ( 0.00841657438250343 ); GO:0060263 regulation of respiratory burst ( 0.00841657438250343 ); GO:0002218 activation of innate immune response ( 0.00981267917042006 ); GO:0002758 innate immune response-activating signal transduction ( 0.00981267917042006 ); GO:0032720 negative regulation of tumor necrosis factor production ( 0.00981267917042006 ); GO:0032755 positive regulation of interleukin-6 production ( 0.00981267917042006 ); GO:0032760 positive regulation of tumor necrosis factor production ( 0.00981267917042006 ); GO:0005875 microtubule associated complex ( 0.00989004071473459 ); ----------------KEGG-------------- hsa04620 Toll-like receptor signaling pathway ( 0.00868509078969635 ); hsa00910 Nitrogen metabolism ( 0.0332584549362636 ); hsa04060 Cytokine-cytokine receptor interaction ( 0.049727259467572 ); ----------------CARTA-------------- ( 0.0153781676303548 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3051 ========================= ----------------C2-------------- REACTOME_M_G1_TRANSITION ( 8.50943521870688e-05 ); REACTOME_ORC1_REMOVAL_FROM_CHROMATIN ( 9.37155462188618e-05 ); REACTOME_UNWINDING_OF_DNA ( 0.000104255549274723 ); REACTOME_DNA_REPLICATION_PRE_INITIATION ( 0.000163885161845565 ); REACTOME_SYNTHESIS_OF_DNA ( 0.000261523167331045 ); BIOCARTA_MCM_PATHWAY ( 0.000288257015211883 ); REACTOME_G1_S_TRANSITION ( 0.000379463778870457 ); REACTOME_S_PHASE ( 0.000401934475345564 ); REACTOME_CELL_CYCLE_CHECKPOINTS ( 0.000474437440301839 ); REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX ( 0.000811038229692884 ); REACTOME_DNA_STRAND_ELONGATION ( 0.000866217926744964 ); KEGG_DNA_REPLICATION ( 0.00116849242923043 ); REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS ( 0.00123418962920218 ); REACTOME_MITOTIC_M_M_G1_PHASES ( 0.00136679016703733 ); REACTOME_G2_M_CHECKPOINTS ( 0.00158863006786582 ); REACTOME_METABLISM_OF_NUCLEOTIDES ( 0.00434887104297896 ); KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION ( 0.00538150355262607 ); REACTOME_CELL_CYCLE_MITOTIC ( 0.00864778464204639 ); ----------------C3-------------- V$E2F_Q3 ( 0.00146911816962719 ); GKCGCNNNNNNNTGAYG_UNKNOWN ( 0.00151429689348903 ); V$E2F_Q6_01 ( 0.00163145218249268 ); V$E2F_Q4_01 ( 0.00174568493774636 ); V$E2F_03 ( 0.00177500550698341 ); V$E2F1_Q3 ( 0.00180463341758666 ); CACGTG_V$MYC_Q2 ( 0.00319714781558686 ); GGGYGTGNY_UNKNOWN ( 0.00436167611062753 ); GGAANCGGAANY_UNKNOWN ( 0.00537033683383134 ); ----------------C4-------------- MORF_BUB3 ( 2.76855844260963e-05 ); module_17 ( 0.000110838770641312 ); MORF_PCNA ( 0.000151404209612084 ); MORF_FBL ( 0.000674957393387028 ); MORF_RFC4 ( 0.000942409177144995 ); MORF_RAD23A ( 0.000957740498283789 ); MORF_RPA2 ( 0.0016879610572841 ); MORF_DAP3 ( 0.00189537300563988 ); module_259 ( 0.00190304931558529 ); MORF_AATF ( 0.00195742431259776 ); MORF_SMC1L1 ( 0.00207044639691021 ); GNF2_FEN1 ( 0.00215667574524428 ); GNF2_MCM4 ( 0.00224458620520589 ); GNF2_MCM5 ( 0.00233417321759288 ); module_85 ( 0.00233417321759288 ); MORF_MSH2 ( 0.00251835870638739 ); module_57 ( 0.00261294810790121 ); GNF2_CENPF ( 0.00280709760298208 ); GNF2_RFC4 ( 0.00290664867363979 ); module_199 ( 0.00290664867363979 ); MORF_ESPL1 ( 0.0030078446254937 ); MORF_FEN1 ( 0.00311068096865453 ); MORF_CDK2 ( 0.00342898757601567 ); GNF2_CCNA2 ( 0.00342898757601567 ); GNF2_PCNA ( 0.00342898757601567 ); MORF_DDB1 ( 0.00356437335502586 ); MORF_EIF3S2 ( 0.00361003665121888 ); MORF_HDAC1 ( 0.00379628339424597 ); MORF_DEK ( 0.00403724404517273 ); GNF2_PA2G4 ( 0.00472013690618277 ); MORF_RAN ( 0.00481550212134896 ); GNF2_SMC4L1 ( 0.00510556942540739 ); MORF_HDAC2 ( 0.00538150355262607 ); MORF_CSNK2B ( 0.00555880169113588 ); MORF_PRDX3 ( 0.00564131377563278 ); GNF2_RRM1 ( 0.00591846578662542 ); MORF_GNB1 ( 0.006898812431671 ); MORF_RAD54L ( 0.00755165366190529 ); module_170 ( 0.00835389227896259 ); module_177 ( 0.00885288123435949 ); MORF_ERH ( 0.0093649677605817 ); MORF_DNMT1 ( 0.00971358029428759 ); GCM_APEX1 ( 0.00971358029428759 ); module_376 ( 0.00981267917042006 ); ----------------C5-------------- CHROMATIN ( 1.58586799326278e-05 ); INTRACELLULAR_ORGANELLE_PART ( 0.000128974172705233 ); ORGANELLE_PART ( 0.000132948837700237 ); CHROMOSOMAL_PART ( 0.000326873569259688 ); DNA_REPLICATION ( 0.000368539192323107 ); INTERLEUKIN_BINDING ( 0.000517283769907633 ); CHROMOSOME ( 0.000674957393387028 ); GROWTH_FACTOR_BINDING ( 0.000866217926744964 ); NUCLEAR_CHROMOSOME_PART ( 0.00104232625390442 ); MITOCHONDRION ( 0.00113670208713695 ); CYTOPLASM ( 0.00138055757627467 ); NON_MEMBRANE_BOUND_ORGANELLE ( 0.00150260509231818 ); INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE ( 0.00150260509231818 ); CYTOKINE_BINDING ( 0.00190304931558529 ); NUCLEAR_CHROMOSOME ( 0.00261294810790121 ); LIGASE_ACTIVITY__FORMING_CARBON_NITROGEN_BONDS ( 0.00410928908059996 ); DNA_METABOLIC_PROCESS ( 0.00515050986093382 ); NUCLEAR_PART ( 0.00672512820587858 ); MITOCHONDRIAL_ENVELOPE ( 0.00770914098617887 ); LIGASE_ACTIVITY ( 0.00819049250182764 ); PROTEIN_TARGETING ( 0.00919282384019519 ); ----------------GOSLIM-------------- GO:0019955 cytokine binding ( 0.00304403731529335 ); GO:0000785 chromatin ( 0.0057431698126293 ); GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor ( 0.00860231935026803 ); GO:0006268 DNA unwinding during replication ( 0.00998214513016433 ); GO:0006261 DNA-dependent DNA replication ( 0.00304403731529335 ); GO:0044454 nuclear chromosome part ( 0.0057431698126293 ); GO:0032392 DNA geometric change ( 0.00860231935026803 ); GO:0032508 DNA duplex unwinding ( 0.00998214513016433 ); GO:0006541 glutamine metabolic process ( 0.00304403731529335 ); GO:0005575 cellular_component ( 0.0057431698126293 ); GO:0043229 intracellular organelle ( 0.00860231935026803 ); GO:0043226 organelle ( 0.00998214513016433 ); GO:0044424 intracellular part ( 0.00304403731529335 ); GO:0043228 non-membrane-bounded organelle ( 0.0057431698126293 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.00860231935026803 ); GO:0000228 nuclear chromosome ( 0.00998214513016433 ); GO:0006270 DNA replication initiation ( 0.00304403731529335 ); GO:0044427 chromosomal part ( 0.0057431698126293 ); GO:0044464 cell part ( 0.00860231935026803 ); GO:0005623 cell ( 0.00998214513016433 ); GO:0005622 intracellular ( 0.00304403731529335 ); GO:0043231 intracellular membrane-bounded organelle ( 0.0057431698126293 ); GO:0043227 membrane-bounded organelle ( 0.00860231935026803 ); GO:0005694 chromosome ( 0.00998214513016433 ); GO:0042555 MCM complex ( 0.00304403731529335 ); GO:0001532 interleukin-21 receptor activity ( 0.0057431698126293 ); GO:0004070 aspartate carbamoyltransferase activity ( 0.00860231935026803 ); GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ( 0.00998214513016433 ); GO:0004151 dihydroorotase activity ( 0.00304403731529335 ); GO:0004642 phosphoribosylformylglycinamidine synthase activity ( 0.0057431698126293 ); GO:0019977 interleukin-21 binding ( 0.00860231935026803 ); GO:0009064 glutamine family amino acid metabolic process ( 0.00998214513016433 ); GO:0005739 mitochondrion ( 0.00304403731529335 ); GO:0004896 cytokine receptor activity ( 0.0057431698126293 ); GO:0004086 carbamoyl-phosphate synthase activity ( 0.00860231935026803 ); GO:0004912 interleukin-3 receptor activity ( 0.00998214513016433 ); GO:0005019 platelet-derived growth factor beta-receptor activity ( 0.00304403731529335 ); GO:0005093 Rab GDP-dissociation inhibitor activity ( 0.0057431698126293 ); GO:0016743 carboxyl- or carbamoyltransferase activity ( 0.00860231935026803 ); GO:0019978 interleukin-3 binding ( 0.00998214513016433 ); GO:0005737 cytoplasm ( 0.00304403731529335 ); GO:0006260 DNA replication ( 0.0057431698126293 ); GO:0006334 nucleosome assembly ( 0.00860231935026803 ); GO:0006259 DNA metabolic process ( 0.00998214513016433 ); GO:0006189 'de novo' IMP biosynthetic process ( 0.00304403731529335 ); GO:0006207 'de novo' pyrimidine base biosynthetic process ( 0.0057431698126293 ); GO:0019856 pyrimidine base biosynthetic process ( 0.00860231935026803 ); GO:0004992 platelet activating factor receptor activity ( 0.00998214513016433 ); GO:0005017 platelet-derived growth factor receptor activity ( 0.00304403731529335 ); GO:0031497 chromatin assembly ( 0.0057431698126293 ); GO:0034728 nucleosome organization ( 0.00860231935026803 ); GO:0006188 IMP biosynthetic process ( 0.00998214513016433 ); GO:0008053 mitochondrial fusion ( 0.00304403731529335 ); GO:0046040 IMP metabolic process ( 0.0057431698126293 ); GO:0046580 negative regulation of Ras protein signal transduction ( 0.00860231935026803 ); GO:0051058 negative regulation of small GTPase mediated signal transduction ( 0.00998214513016433 ); GO:0005664 nuclear origin of replication recognition complex ( 0.00304403731529335 ); GO:0004095 carnitine O-palmitoyltransferase activity ( 0.0057431698126293 ); GO:0016416 O-palmitoyltransferase activity ( 0.00860231935026803 ); GO:0005515 protein binding ( 0.00998214513016433 ); GO:0002507 tolerance induction ( 0.00304403731529335 ); GO:0000808 origin recognition complex ( 0.0057431698126293 ); GO:0019838 growth factor binding ( 0.00860231935026803 ); GO:0006323 DNA packaging ( 0.00998214513016433 ); GO:0003688 DNA replication origin binding ( 0.00304403731529335 ); GO:0005092 GDP-dissociation inhibitor activity ( 0.0057431698126293 ); GO:0016406 carnitine O-acyltransferase activity ( 0.00860231935026803 ); GO:0006310 DNA recombination ( 0.00998214513016433 ); GO:0042254 ribosome biogenesis ( 0.00304403731529335 ); GO:0006206 pyrimidine base metabolic process ( 0.0057431698126293 ); GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ( 0.00860231935026803 ); ----------------GO-------------- GO:0019955 cytokine binding ( 1.26120118647453e-05 ); GO:0000785 chromatin ( 2.97052031326322e-05 ); GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor ( 8.53743488961253e-05 ); GO:0006268 DNA unwinding during replication ( 0.000124997709328498 ); GO:0006261 DNA-dependent DNA replication ( 0.000139558924583945 ); GO:0044454 nuclear chromosome part ( 0.000157564292885291 ); GO:0032392 DNA geometric change ( 0.000198340983963368 ); GO:0032508 DNA duplex unwinding ( 0.000198340983963368 ); GO:0006541 glutamine metabolic process ( 0.000256451694095927 ); GO:0005575 cellular_component ( 0.000294959514695904 ); GO:0043229 intracellular organelle ( 0.000325850598795169 ); GO:0043226 organelle ( 0.000327814295980522 ); GO:0044424 intracellular part ( 0.000354237509656665 ); GO:0043228 non-membrane-bounded organelle ( 0.000359735215973846 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.000359735215973846 ); GO:0000228 nuclear chromosome ( 0.000368539192323107 ); GO:0006270 DNA replication initiation ( 0.000474589731509737 ); GO:0044427 chromosomal part ( 0.000533057511283122 ); GO:0044464 cell part ( 0.000548964656014135 ); GO:0005623 cell ( 0.000549952940190149 ); GO:0005622 intracellular ( 0.000766321414233737 ); GO:0043231 intracellular membrane-bounded organelle ( 0.000865156975106071 ); GO:0043227 membrane-bounded organelle ( 0.000870208982373582 ); GO:0005694 chromosome ( 0.00135227506196664 ); GO:0042555 MCM complex ( 0.00140753028703566 ); GO:0001532 interleukin-21 receptor activity ( 0.00140753028703566 ); GO:0004070 aspartate carbamoyltransferase activity ( 0.00140753028703566 ); GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ( 0.00140753028703566 ); GO:0004151 dihydroorotase activity ( 0.00140753028703566 ); GO:0004642 phosphoribosylformylglycinamidine synthase activity ( 0.00140753028703566 ); GO:0019977 interleukin-21 binding ( 0.00140753028703566 ); GO:0009064 glutamine family amino acid metabolic process ( 0.00198590272813339 ); GO:0005739 mitochondrion ( 0.00198992750929433 ); GO:0004896 cytokine receptor activity ( 0.00251835870638739 ); GO:0004086 carbamoyl-phosphate synthase activity ( 0.00281315009157812 ); GO:0004912 interleukin-3 receptor activity ( 0.00281315009157812 ); GO:0005019 platelet-derived growth factor beta-receptor activity ( 0.00281315009157812 ); GO:0005093 Rab GDP-dissociation inhibitor activity ( 0.00281315009157812 ); GO:0016743 carboxyl- or carbamoyltransferase activity ( 0.00281315009157812 ); GO:0019978 interleukin-3 binding ( 0.00281315009157812 ); GO:0005737 cytoplasm ( 0.00327290262893657 ); GO:0006260 DNA replication ( 0.00347411849108606 ); GO:0006334 nucleosome assembly ( 0.00387609097935412 ); GO:0006259 DNA metabolic process ( 0.00404792299577207 ); GO:0006189 'de novo' IMP biosynthetic process ( 0.00421686191086512 ); GO:0006207 'de novo' pyrimidine base biosynthetic process ( 0.00421686191086512 ); GO:0019856 pyrimidine base biosynthetic process ( 0.00421686191086512 ); GO:0004992 platelet activating factor receptor activity ( 0.00421686191086512 ); GO:0005017 platelet-derived growth factor receptor activity ( 0.00421686191086512 ); GO:0031497 chromatin assembly ( 0.004471044987259 ); GO:0034728 nucleosome organization ( 0.00497552510268208 ); GO:0006188 IMP biosynthetic process ( 0.00561866823899482 ); GO:0008053 mitochondrial fusion ( 0.00561866823899482 ); GO:0046040 IMP metabolic process ( 0.00561866823899482 ); GO:0046580 negative regulation of Ras protein signal transduction ( 0.00561866823899482 ); GO:0051058 negative regulation of small GTPase mediated signal transduction ( 0.00561866823899482 ); GO:0005664 nuclear origin of replication recognition complex ( 0.00561866823899482 ); GO:0004095 carnitine O-palmitoyltransferase activity ( 0.00561866823899482 ); GO:0016416 O-palmitoyltransferase activity ( 0.00561866823899482 ); GO:0005515 protein binding ( 0.0057437302899517 ); GO:0002507 tolerance induction ( 0.0070185715669302 ); GO:0000808 origin recognition complex ( 0.0070185715669302 ); GO:0019838 growth factor binding ( 0.00708813987676548 ); GO:0006323 DNA packaging ( 0.00835389227896259 ); GO:0003688 DNA replication origin binding ( 0.00841657438250343 ); GO:0005092 GDP-dissociation inhibitor activity ( 0.00841657438250343 ); GO:0016406 carnitine O-acyltransferase activity ( 0.00841657438250343 ); GO:0006310 DNA recombination ( 0.00851875975774888 ); GO:0042254 ribosome biogenesis ( 0.00953855461208555 ); GO:0006206 pyrimidine base metabolic process ( 0.00981267917042006 ); GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ( 0.00981267917042006 ); ----------------KEGG-------------- hsa03030 DNA replication ( 0.00116849242923043 ); hsa04060 Cytokine-cytokine receptor interaction ( 0.00538150355262607 ); hsa04110 Cell cycle ( 0.0107937212107607 ); hsa04630 Jak-STAT signaling pathway ( 0.0194890495020382 ); hsa00251 Glutamate metabolism ( 0.0332584549362636 ); hsa00252 Alanine and aspartate metabolism ( 0.0386968027071392 ); ----------------CARTA-------------- longevitypathway ( 0.000656134559216271 ); il7pathway ( 0.0181495880674649 ); il6pathway ( 0.0195324759715956 ); nkcellspathway ( 0.0305281677431948 ); hdacpathway ( 0.0318942394709986 ); g2pathway ( 0.0373399880320612 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.000859773741730313 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00113994324117838 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00169613692277109 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.00733001535081775 ); TIAL1_iCLIP_(Wang_2010) ( 0.0219405099593624 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0316572289568323 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0399692723933927 ); ----------------immu-------------- ( 0.00857017884541265 ); ----------------ARE-------------- ( ); ============================ group3193 ========================= ----------------C2-------------- KEGG_P53_SIGNALING_PATHWAY ( 0.000112627808807358 ); KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION ( 0.00605934670932718 ); KEGG_SMALL_CELL_LUNG_CANCER ( 0.00620175853539602 ); REACTOME_DNA_REPAIR ( 0.00902212695932432 ); ----------------C3-------------- ( 0.00211807373547229 ); ----------------C4-------------- module_379 ( 0.00242749686387545 ); module_242 ( 0.00280266820920986 ); module_411 ( 0.00497552510268208 ); module_341 ( 0.00550505127018847 ); module_181 ( 0.00759891579561857 ); ----------------C5-------------- DAMAGED_DNA_BINDING ( 0.000394614722836035 ); TRANSLATION_FACTOR_ACTIVITY__NUCLEIC_ACID_BINDING ( 0.00137078888488894 ); TRANSLATION_REGULATOR_ACTIVITY ( 0.00151429689348903 ); ----------------GOSLIM-------------- GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ( ); GO:0030887 positive regulation of myeloid dendritic cell activation ( ); GO:0031117 positive regulation of microtubule depolymerization ( ); GO:0008352 katanin complex ( ); GO:0004686 elongation factor-2 kinase activity ( ); GO:0010302 2-oxoglutarate-dependent dioxygenase activity ( ); GO:0051747 DNA demethylase activity ( ); GO:0016491 oxidoreductase activity ( ); GO:0003684 damaged DNA binding ( ); GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ( ); GO:0051213 dioxygenase activity ( ); GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen ( ); GO:0030885 regulation of myeloid dendritic cell activation ( ); GO:0001766 membrane raft polarization ( ); GO:0016925 protein sumoylation ( ); GO:0031580 membrane raft distribution ( ); GO:0043243 positive regulation of protein complex disassembly ( ); GO:0051665 membrane raft localization ( ); GO:0051865 protein autoubiquitination ( ); GO:0019789 SUMO ligase activity ( ); GO:0006290 pyrimidine dimer repair ( ); GO:0008568 microtubule-severing ATPase activity ( ); GO:0032451 demethylase activity ( ); GO:0005506 iron ion binding ( ); GO:0031579 membrane raft organization ( ); GO:0045502 dynein binding ( ); GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity ( ); GO:0008135 translation factor activity, nucleic acid binding ( ); GO:0055114 oxidation reduction ( ); GO:0022836 gated channel activity ( ); GO:0005829 cytosol ( ); GO:0003824 catalytic activity ( ); GO:0031112 positive regulation of microtubule polymerization or depolymerization ( ); GO:0032446 protein modification by small protein conjugation ( ); GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ( ); GO:0005123 death receptor binding ( ); GO:0015277 kainate selective glutamate receptor activity ( ); ----------------GO-------------- GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ( 0.000474589731509737 ); GO:0030887 positive regulation of myeloid dendritic cell activation ( 0.00140753028703566 ); GO:0031117 positive regulation of microtubule depolymerization ( 0.00140753028703566 ); GO:0008352 katanin complex ( 0.00140753028703566 ); GO:0004686 elongation factor-2 kinase activity ( 0.00140753028703566 ); GO:0010302 2-oxoglutarate-dependent dioxygenase activity ( 0.00140753028703566 ); GO:0051747 DNA demethylase activity ( 0.00140753028703566 ); GO:0016491 oxidoreductase activity ( 0.00161368684869076 ); GO:0003684 damaged DNA binding ( 0.00166467651345231 ); GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ( 0.00207044639691021 ); GO:0051213 dioxygenase activity ( 0.00207044639691021 ); GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen ( 0.00215667574524428 ); GO:0030885 regulation of myeloid dendritic cell activation ( 0.00281315009157812 ); GO:0001766 membrane raft polarization ( 0.00421686191086512 ); GO:0016925 protein sumoylation ( 0.00421686191086512 ); GO:0031580 membrane raft distribution ( 0.00421686191086512 ); GO:0043243 positive regulation of protein complex disassembly ( 0.00421686191086512 ); GO:0051665 membrane raft localization ( 0.00421686191086512 ); GO:0051865 protein autoubiquitination ( 0.00421686191086512 ); GO:0019789 SUMO ligase activity ( 0.00421686191086512 ); GO:0006290 pyrimidine dimer repair ( 0.00561866823899482 ); GO:0008568 microtubule-severing ATPase activity ( 0.00561866823899482 ); GO:0032451 demethylase activity ( 0.00561866823899482 ); GO:0005506 iron ion binding ( 0.0062389465069844 ); GO:0031579 membrane raft organization ( 0.0070185715669302 ); GO:0045502 dynein binding ( 0.0070185715669302 ); GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity ( 0.0070185715669302 ); GO:0008135 translation factor activity, nucleic acid binding ( 0.00739565490286539 ); GO:0055114 oxidation reduction ( 0.00757777112215446 ); GO:0022836 gated channel activity ( 0.00789035850684483 ); GO:0005829 cytosol ( 0.00806235871589667 ); GO:0003824 catalytic activity ( 0.0081171235458686 ); GO:0031112 positive regulation of microtubule polymerization or depolymerization ( 0.00841657438250343 ); GO:0032446 protein modification by small protein conjugation ( 0.00885288123435949 ); GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ( 0.0093649677605817 ); GO:0005123 death receptor binding ( 0.00981267917042006 ); GO:0015277 kainate selective glutamate receptor activity ( 0.00981267917042006 ); ----------------KEGG-------------- hsa04115 p53 signaling pathway ( 0.000112627808807358 ); hsa05222 Small cell lung cancer ( 0.00649115782287193 ); hsa04120 Ubiquitin mediated proteolysis ( 0.014545010429453 ); hsa04630 Jak-STAT signaling pathway ( 0.0194890495020382 ); ----------------CARTA-------------- pitx2pathway ( 0.000321889183140706 ); wntpathway ( 0.000394614722836035 ); ps1pathway ( 0.000608060960915165 ); gsk3pathway ( 0.000705991804951034 ); hespathway ( 0.0181495880674649 ); telpathway ( 0.0181495880674649 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2621 ========================= ----------------C2-------------- ( ); ----------------C3-------------- RYAAAKNNNNNNTTGW_UNKNOWN ( 0.00416124677140607 ); V$EN1_01 ( 0.00577452305718952 ); TMTCGCGANR_UNKNOWN ( 0.00778199305899028 ); AAAGGAT,MIR-501 ( 0.00954919144030242 ); ----------------C4-------------- module_285 ( 0.00162024502990792 ); MORF_RAB1A ( 0.00170330034982541 ); MORF_DDB1 ( 0.00320839961420677 ); MORF_RAF1 ( 0.00703351492652274 ); MORF_PHB ( 0.00988801944151588 ); ----------------C5-------------- ( 0.00831492515670834 ); ----------------GOSLIM-------------- GO:0048037 cofactor binding ( 0.00407049607839048 ); GO:0004386 helicase activity ( 0.00886956853133141 ); GO:0050662 coenzyme binding ( 0.00407049607839048 ); GO:0003978 UDP-glucose 4-epimerase activity ( 0.00886956853133141 ); GO:0008470 isovaleryl-CoA dehydrogenase activity ( 0.00407049607839048 ); GO:0009439 cyanate metabolic process ( 0.00886956853133141 ); GO:0009440 cyanate catabolic process ( 0.00407049607839048 ); GO:0019754 one-carbon compound catabolic process ( 0.00886956853133141 ); GO:0005736 DNA-directed RNA polymerase I complex ( 0.00407049607839048 ); GO:0004792 thiosulfate sulfurtransferase activity ( 0.00886956853133141 ); GO:0008184 glycogen phosphorylase activity ( 0.00407049607839048 ); GO:0005771 multivesicular body ( 0.00886956853133141 ); GO:0004645 phosphorylase activity ( 0.00407049607839048 ); GO:0016783 sulfurtransferase activity ( 0.00886956853133141 ); GO:0003824 catalytic activity ( 0.00407049607839048 ); GO:0008026 ATP-dependent helicase activity ( 0.00886956853133141 ); GO:0070035 purine NTP-dependent helicase activity ( 0.00407049607839048 ); GO:0005980 glycogen catabolic process ( 0.00886956853133141 ); GO:0030976 thiamin pyrophosphate binding ( 0.00407049607839048 ); GO:0009251 glucan catabolic process ( 0.00886956853133141 ); GO:0006012 galactose metabolic process ( 0.00407049607839048 ); GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives ( 0.00886956853133141 ); GO:0003723 RNA binding ( 0.00407049607839048 ); ----------------GO-------------- GO:0048037 cofactor binding ( 0.000168748550755192 ); GO:0004386 helicase activity ( 0.000793504604637489 ); GO:0050662 coenzyme binding ( 0.00101529679757264 ); GO:0003978 UDP-glucose 4-epimerase activity ( 0.0013572613482129 ); GO:0008470 isovaleryl-CoA dehydrogenase activity ( 0.0013572613482129 ); GO:0009439 cyanate metabolic process ( 0.00271274867696791 ); GO:0009440 cyanate catabolic process ( 0.00271274867696791 ); GO:0019754 one-carbon compound catabolic process ( 0.00271274867696791 ); GO:0005736 DNA-directed RNA polymerase I complex ( 0.00271274867696791 ); GO:0004792 thiosulfate sulfurtransferase activity ( 0.00271274867696791 ); GO:0008184 glycogen phosphorylase activity ( 0.0040664642159417 ); GO:0005771 multivesicular body ( 0.00541841019211919 ); GO:0004645 phosphorylase activity ( 0.00541841019211919 ); GO:0016783 sulfurtransferase activity ( 0.00541841019211919 ); GO:0003824 catalytic activity ( 0.00555854813042716 ); GO:0008026 ATP-dependent helicase activity ( 0.00660115036352409 ); GO:0070035 purine NTP-dependent helicase activity ( 0.00660115036352409 ); GO:0005980 glycogen catabolic process ( 0.00676858882979903 ); GO:0030976 thiamin pyrophosphate binding ( 0.00676858882979903 ); GO:0009251 glucan catabolic process ( 0.00811700235059531 ); GO:0006012 galactose metabolic process ( 0.00946365297344076 ); GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives ( 0.00946365297344076 ); GO:0003723 RNA binding ( 0.00995901740871366 ); ----------------KEGG-------------- hsa00520 Nucleotide sugars metabolism ( 0.00811700235059531 ); hsa00052 Galactose metabolism ( 0.0334044222539536 ); hsa03020 RNA polymerase ( 0.0334044222539536 ); hsa00790 Folate biosynthesis ( 0.0438649979729967 ); ----------------CARTA-------------- melanocytepathway ( 0.0175066597767723 ); gabapathway ( 0.0215045429720881 ); mef2dpathway ( 0.0320891273946076 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.000183249647355437 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00793743377832356 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0287254272137548 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0364027919459981 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3002 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0003989 acetyl-CoA carboxylase activity ( ); GO:0007099 centriole replication ( ); GO:0005784 translocon complex ( ); GO:0004075 biotin carboxylase activity ( ); GO:0051798 positive regulation of hair follicle development ( ); GO:0015379 potassium:chloride symporter activity ( ); GO:0042634 regulation of hair cycle ( ); GO:0045684 positive regulation of epidermis development ( ); GO:0051299 centrosome separation ( ); GO:0051797 regulation of hair follicle development ( ); GO:0009374 biotin binding ( ); GO:0016421 CoA carboxylase activity ( ); GO:0015377 cation:chloride symporter activity ( ); GO:0016885 ligase activity, forming carbon-carbon bonds ( ); GO:0046875 ephrin receptor binding ( ); ----------------GO-------------- GO:0003989 acetyl-CoA carboxylase activity ( 0.00271274867696791 ); GO:0007099 centriole replication ( 0.0040664642159417 ); GO:0005784 translocon complex ( 0.0040664642159417 ); GO:0004075 biotin carboxylase activity ( 0.0040664642159417 ); GO:0051798 positive regulation of hair follicle development ( 0.00541841019211919 ); GO:0015379 potassium:chloride symporter activity ( 0.00541841019211919 ); GO:0042634 regulation of hair cycle ( 0.00676858882979903 ); GO:0045684 positive regulation of epidermis development ( 0.00676858882979903 ); GO:0051299 centrosome separation ( 0.00676858882979903 ); GO:0051797 regulation of hair follicle development ( 0.00676858882979903 ); GO:0009374 biotin binding ( 0.00676858882979903 ); GO:0016421 CoA carboxylase activity ( 0.00811700235059531 ); GO:0015377 cation:chloride symporter activity ( 0.00946365297344076 ); GO:0016885 ligase activity, forming carbon-carbon bonds ( 0.00946365297344076 ); GO:0046875 ephrin receptor binding ( 0.00946365297344076 ); ----------------KEGG-------------- hsa00625 Tetrachloroethene degradation ( 0.0040664642159417 ); hsa00363 Bisphenol A degradation ( 0.00676858882979903 ); hsa00061 Fatty acid biosynthesis ( 0.00811700235059531 ); hsa00591 Linoleic acid metabolism ( 0.0373399880320606 ); hsa00120 Bile acid biosynthesis ( 0.0425634125613438 ); hsa00051 Fructose and mannose metabolism ( 0.0464630589745387 ); hsa00640 Propanoate metabolism ( 0.0464630589745387 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3100 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$MZF1_02 ( 0.00147478741330243 ); V$GR_Q6_01 ( 0.00210245399657841 ); GTGTTGA,MIR-505 ( 0.00536140591003485 ); CGTSACG_V$PAX3_B ( 0.00722860109304256 ); CYTAGCAAY_UNKNOWN ( 0.00795714896260929 ); V$PR_01 ( 0.008562903799168 ); V$PR_02 ( 0.00887334728503136 ); ----------------C4-------------- GNF2_CKS1B ( 0.00100694386603201 ); module_3 ( 0.00131169205956702 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0001301 progressive alteration of chromatin during cell aging ( 0.00164939671331869 ); GO:0001304 progressive alteration of chromatin during replicative cell aging ( 0.00806832053460303 ); GO:0001309 age-dependent telomere shortening ( 0.00164939671331869 ); GO:0031627 telomeric loop formation ( 0.00806832053460303 ); GO:0003937 IMP cyclohydrolase activity ( 0.00164939671331869 ); GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity ( 0.00806832053460303 ); GO:0015320 phosphate carrier activity ( 0.00164939671331869 ); GO:0016971 flavin-linked sulfhydryl oxidase activity ( 0.00806832053460303 ); GO:0032201 telomere maintenance via semi-conservative replication ( 0.00164939671331869 ); GO:0032213 regulation of telomere maintenance via semi-conservative replication ( 0.00806832053460303 ); GO:0032214 negative regulation of telomere maintenance via semi-conservative replication ( 0.00164939671331869 ); GO:0016312 inositol bisphosphate phosphatase activity ( 0.00806832053460303 ); GO:0001302 replicative cell aging ( 0.00164939671331869 ); GO:0010834 telomere maintenance via telomere shortening ( 0.00806832053460303 ); GO:0031848 protection from non-homologous end joining at telomere ( 0.00164939671331869 ); GO:0043247 telomere maintenance in response to DNA damage ( 0.00806832053460303 ); GO:0016972 thiol oxidase activity ( 0.00164939671331869 ); GO:0006188 IMP biosynthetic process ( 0.00806832053460303 ); GO:0016233 telomere capping ( 0.00164939671331869 ); GO:0046040 IMP metabolic process ( 0.00806832053460303 ); GO:0030870 Mre11 complex ( 0.00164939671331869 ); GO:0031143 pseudopodium ( 0.00806832053460303 ); GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity ( 0.00164939671331869 ); GO:0031100 organ regeneration ( 0.00806832053460303 ); GO:0032206 positive regulation of telomere maintenance ( 0.00164939671331869 ); GO:0070198 protein localization to telomere ( 0.00806832053460303 ); GO:0003691 double-stranded telomeric DNA binding ( 0.00164939671331869 ); GO:0019238 cyclohydrolase activity ( 0.00806832053460303 ); GO:0044446 intracellular organelle part ( 0.00164939671331869 ); GO:0044422 organelle part ( 0.00806832053460303 ); GO:0006467 protein thiol-disulfide exchange ( 0.00164939671331869 ); GO:0034502 protein localization to chromosome ( 0.00806832053460303 ); GO:0016670 oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor ( 0.00164939671331869 ); GO:0016742 hydroxymethyl-, formyl- and related transferase activity ( 0.00806832053460303 ); GO:0010149 senescence ( 0.00164939671331869 ); GO:0004029 aldehyde dehydrogenase (NAD) activity ( 0.00806832053460303 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.00164939671331869 ); GO:0015280 amiloride-sensitive sodium channel activity ( 0.00806832053460303 ); GO:0017166 vinculin binding ( 0.00164939671331869 ); GO:0042577 lipid phosphatase activity ( 0.00806832053460303 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.00164939671331869 ); ----------------GO-------------- GO:0001301 progressive alteration of chromatin during cell aging ( 0.00130699240938992 ); GO:0001304 progressive alteration of chromatin during replicative cell aging ( 0.00130699240938992 ); GO:0001309 age-dependent telomere shortening ( 0.00130699240938992 ); GO:0031627 telomeric loop formation ( 0.00130699240938992 ); GO:0003937 IMP cyclohydrolase activity ( 0.00130699240938992 ); GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity ( 0.00130699240938992 ); GO:0015320 phosphate carrier activity ( 0.00130699240938992 ); GO:0016971 flavin-linked sulfhydryl oxidase activity ( 0.00130699240938992 ); GO:0032201 telomere maintenance via semi-conservative replication ( 0.00261234220817141 ); GO:0032213 regulation of telomere maintenance via semi-conservative replication ( 0.00261234220817141 ); GO:0032214 negative regulation of telomere maintenance via semi-conservative replication ( 0.00261234220817141 ); GO:0016312 inositol bisphosphate phosphatase activity ( 0.00261234220817141 ); GO:0001302 replicative cell aging ( 0.00391605137827788 ); GO:0010834 telomere maintenance via telomere shortening ( 0.00391605137827788 ); GO:0031848 protection from non-homologous end joining at telomere ( 0.00391605137827788 ); GO:0043247 telomere maintenance in response to DNA damage ( 0.00391605137827788 ); GO:0016972 thiol oxidase activity ( 0.00391605137827788 ); GO:0006188 IMP biosynthetic process ( 0.00521812189935222 ); GO:0016233 telomere capping ( 0.00521812189935222 ); GO:0046040 IMP metabolic process ( 0.00521812189935222 ); GO:0030870 Mre11 complex ( 0.00521812189935222 ); GO:0031143 pseudopodium ( 0.00521812189935222 ); GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity ( 0.00521812189935222 ); GO:0031100 organ regeneration ( 0.00651855574874682 ); GO:0032206 positive regulation of telomere maintenance ( 0.00651855574874682 ); GO:0070198 protein localization to telomere ( 0.00651855574874682 ); GO:0003691 double-stranded telomeric DNA binding ( 0.00651855574874682 ); GO:0019238 cyclohydrolase activity ( 0.00651855574874682 ); GO:0044446 intracellular organelle part ( 0.00711175380682028 ); GO:0044422 organelle part ( 0.00735530646634831 ); GO:0006467 protein thiol-disulfide exchange ( 0.00781735490152935 ); GO:0034502 protein localization to chromosome ( 0.00781735490152935 ); GO:0016670 oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor ( 0.00781735490152935 ); GO:0016742 hydroxymethyl-, formyl- and related transferase activity ( 0.00781735490152935 ); GO:0010149 senescence ( 0.00911452133048107 ); GO:0004029 aldehyde dehydrogenase (NAD) activity ( 0.00911452133048107 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.00911452133048107 ); GO:0015280 amiloride-sensitive sodium channel activity ( 0.00911452133048107 ); GO:0017166 vinculin binding ( 0.00911452133048107 ); GO:0042577 lipid phosphatase activity ( 0.00911452133048107 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.00911452133048107 ); ----------------KEGG-------------- hsa00053 Ascorbate and aldarate metabolism ( 0.0117039638966145 ); hsa05322 Systemic lupus erythematosus ( 0.0117117250373154 ); hsa00641 3-Chloroacrylic acid degradation ( 0.0181491353010632 ); hsa00670 One carbon pool by folate ( 0.0207158710002756 ); hsa00903 Limonene and pinene degradation ( 0.0232761542128824 ); hsa00410 beta-Alanine metabolism ( 0.0309184444866537 ); hsa00220 Urea cycle and metabolism of amino groups ( 0.0372430678194287 ); hsa00120 Bile acid biosynthesis ( 0.0410187707263031 ); hsa00340 Histidine metabolism ( 0.0422741713587546 ); hsa00640 Propanoate metabolism ( 0.0447802335945524 ); hsa00650 Butanoate metabolism ( 0.0485275079899226 ); ----------------CARTA-------------- ifnapathway ( 0.0168633428923708 ); nkcellspathway ( 0.0283774254365068 ); ----------------RBP-------------- ( 0.0298155509805573 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2990 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$BRN2_01 ( 0.00154131479042389 ); TTCYRGAA_UNKNOWN ( 0.00256414601396872 ); CYTAGCAAY_UNKNOWN ( 0.00736978386483024 ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00320180082763438 ); ----------------GOSLIM-------------- GO:0002684 positive regulation of immune system process ( ); GO:0050778 positive regulation of immune response ( ); GO:0002682 regulation of immune system process ( ); GO:0032649 regulation of interferon-gamma production ( ); GO:0032609 interferon-gamma production ( ); GO:0048584 positive regulation of response to stimulus ( ); GO:0042102 positive regulation of T cell proliferation ( ); GO:0002252 immune effector process ( ); GO:0050776 regulation of immune response ( ); GO:0050671 positive regulation of lymphocyte proliferation ( ); GO:0032946 positive regulation of mononuclear cell proliferation ( ); GO:0065001 specification of axis polarity ( ); GO:0042129 regulation of T cell proliferation ( ); GO:0050670 regulation of lymphocyte proliferation ( ); GO:0032944 regulation of mononuclear cell proliferation ( ); GO:0042098 T cell proliferation ( ); GO:0050870 positive regulation of T cell activation ( ); GO:0009986 cell surface ( ); GO:0002639 positive regulation of immunoglobulin production ( ); GO:0009597 detection of virus ( ); GO:0032753 positive regulation of interleukin-4 production ( ); GO:0051251 positive regulation of lymphocyte activation ( ); GO:0048583 regulation of response to stimulus ( ); GO:0046651 lymphocyte proliferation ( ); GO:0002696 positive regulation of leukocyte activation ( ); GO:0032943 mononuclear cell proliferation ( ); GO:0050867 positive regulation of cell activation ( ); GO:0005121 Toll binding ( ); GO:0050863 regulation of T cell activation ( ); GO:0042113 B cell activation ( ); GO:0032608 interferon-beta production ( ); GO:0032648 regulation of interferon-beta production ( ); GO:0043372 positive regulation of CD4-positive, alpha beta T cell differentiation ( ); GO:0045350 interferon-beta biosynthetic process ( ); GO:0045356 positive regulation of interferon-alpha biosynthetic process ( ); GO:0045357 regulation of interferon-beta biosynthetic process ( ); GO:0045359 positive regulation of interferon-beta biosynthetic process ( ); GO:0050901 leukocyte tethering or rolling ( ); GO:0004430 1-phosphatidylinositol 4-kinase activity ( ); GO:0002449 lymphocyte mediated immunity ( ); GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains ( ); GO:0002250 adaptive immune response ( ); GO:0030098 lymphocyte differentiation ( ); GO:0002726 positive regulation of T cell cytokine production ( ); GO:0022614 membrane to membrane docking ( ); GO:0032733 positive regulation of interleukin-10 production ( ); GO:0032743 positive regulation of interleukin-2 production ( ); GO:0045349 interferon-alpha biosynthetic process ( ); GO:0045354 regulation of interferon-alpha biosynthetic process ( ); GO:0048873 homeostasis of number of cells within a tissue ( ); GO:0002443 leukocyte mediated immunity ( ); GO:0051249 regulation of lymphocyte activation ( ); GO:0002369 T cell cytokine production ( ); GO:0002724 regulation of T cell cytokine production ( ); GO:0032479 regulation of type I interferon production ( ); GO:0032607 interferon-alpha production ( ); GO:0032633 interleukin-4 production ( ); GO:0032647 regulation of interferon-alpha production ( ); GO:0032673 regulation of interleukin-4 production ( ); GO:0045416 positive regulation of interleukin-8 biosynthetic process ( ); GO:0046622 positive regulation of organ growth ( ); GO:0032729 positive regulation of interferon-gamma production ( ); GO:0032760 positive regulation of tumor necrosis factor production ( ); GO:0043370 regulation of CD4-positive, alpha beta T cell differentiation ( ); GO:0031519 PcG protein complex ( ); GO:0002694 regulation of leukocyte activation ( ); GO:0050865 regulation of cell activation ( ); ----------------GO-------------- GO:0002684 positive regulation of immune system process ( 3.47273191247218e-05 ); GO:0050778 positive regulation of immune response ( 0.000217929327009953 ); GO:0002682 regulation of immune system process ( 0.000321417776350195 ); GO:0032649 regulation of interferon-gamma production ( 0.000344897456811546 ); GO:0032609 interferon-gamma production ( 0.000377453985998193 ); GO:0048584 positive regulation of response to stimulus ( 0.000603368100083047 ); GO:0042102 positive regulation of T cell proliferation ( 0.000645493224089234 ); GO:0002252 immune effector process ( 0.00074495950134099 ); GO:0050776 regulation of immune response ( 0.00074495950134099 ); GO:0050671 positive regulation of lymphocyte proliferation ( 0.000879524225428028 ); GO:0032946 positive regulation of mononuclear cell proliferation ( 0.000930544468067339 ); GO:0065001 specification of axis polarity ( 0.0012567234705676 ); GO:0042129 regulation of T cell proliferation ( 0.00132661555799001 ); GO:0050670 regulation of lymphocyte proliferation ( 0.00179000878287171 ); GO:0032944 regulation of mononuclear cell proliferation ( 0.00186163828155708 ); GO:0042098 T cell proliferation ( 0.00193461567975959 ); GO:0050870 positive regulation of T cell activation ( 0.00200893775203221 ); GO:0009986 cell surface ( 0.00249866268479287 ); GO:0002639 positive regulation of immunoglobulin production ( 0.00251193068518807 ); GO:0009597 detection of virus ( 0.00251193068518807 ); GO:0032753 positive regulation of interleukin-4 production ( 0.00251193068518807 ); GO:0051251 positive regulation of lymphocyte activation ( 0.00273781721399345 ); GO:0048583 regulation of response to stimulus ( 0.00320180082763438 ); GO:0046651 lymphocyte proliferation ( 0.00328295294186272 ); GO:0002696 positive regulation of leukocyte activation ( 0.00347504879914701 ); GO:0032943 mononuclear cell proliferation ( 0.00347504879914701 ); GO:0050867 positive regulation of cell activation ( 0.00367229480383888 ); GO:0005121 Toll binding ( 0.00376562339711195 ); GO:0050863 regulation of T cell activation ( 0.00462296739267681 ); GO:0042113 B cell activation ( 0.00496253155093794 ); GO:0032608 interferon-beta production ( 0.00501780335764856 ); GO:0032648 regulation of interferon-beta production ( 0.00501780335764856 ); GO:0043372 positive regulation of CD4-positive, alpha beta T cell differentiation ( 0.00501780335764856 ); GO:0045350 interferon-beta biosynthetic process ( 0.00501780335764856 ); GO:0045356 positive regulation of interferon-alpha biosynthetic process ( 0.00501780335764856 ); GO:0045357 regulation of interferon-beta biosynthetic process ( 0.00501780335764856 ); GO:0045359 positive regulation of interferon-beta biosynthetic process ( 0.00501780335764856 ); GO:0050901 leukocyte tethering or rolling ( 0.00501780335764856 ); GO:0004430 1-phosphatidylinositol 4-kinase activity ( 0.00501780335764856 ); GO:0002449 lymphocyte mediated immunity ( 0.0050782122403148 ); GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains ( 0.00592256131614644 ); GO:0002250 adaptive immune response ( 0.00604808686055164 ); GO:0030098 lymphocyte differentiation ( 0.00604808686055164 ); GO:0002726 positive regulation of T cell cytokine production ( 0.00626847231617111 ); GO:0022614 membrane to membrane docking ( 0.00626847231617111 ); GO:0032733 positive regulation of interleukin-10 production ( 0.00626847231617111 ); GO:0032743 positive regulation of interleukin-2 production ( 0.00626847231617111 ); GO:0045349 interferon-alpha biosynthetic process ( 0.00626847231617111 ); GO:0045354 regulation of interferon-alpha biosynthetic process ( 0.00626847231617111 ); GO:0048873 homeostasis of number of cells within a tissue ( 0.00626847231617111 ); GO:0002443 leukocyte mediated immunity ( 0.00643195354573312 ); GO:0051249 regulation of lymphocyte activation ( 0.00682669237939868 ); GO:0002369 T cell cytokine production ( 0.00751763202011813 ); GO:0002724 regulation of T cell cytokine production ( 0.00751763202011813 ); GO:0032479 regulation of type I interferon production ( 0.00751763202011813 ); GO:0032607 interferon-alpha production ( 0.00751763202011813 ); GO:0032633 interleukin-4 production ( 0.00751763202011813 ); GO:0032647 regulation of interferon-alpha production ( 0.00751763202011813 ); GO:0032673 regulation of interleukin-4 production ( 0.00751763202011813 ); GO:0045416 positive regulation of interleukin-8 biosynthetic process ( 0.00751763202011813 ); GO:0046622 positive regulation of organ growth ( 0.00751763202011813 ); GO:0032729 positive regulation of interferon-gamma production ( 0.00876528421499356 ); GO:0032760 positive regulation of tumor necrosis factor production ( 0.00876528421499356 ); GO:0043370 regulation of CD4-positive, alpha beta T cell differentiation ( 0.00876528421499356 ); GO:0031519 PcG protein complex ( 0.00876528421499356 ); GO:0002694 regulation of leukocyte activation ( 0.00896066330560041 ); GO:0050865 regulation of cell activation ( 0.00988756836009968 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.023955999164899 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group21 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$GATA6_01 ( 0.00149725466990569 ); GTGGGTGK_UNKNOWN ( 0.00236402698532855 ); V$CDP_02 ( 0.00479292275776134 ); V$PBX1_02 ( 0.00706074810231173 ); ----------------C4-------------- GNF2_CEBPA ( 0.00268672245845603 ); GNF2_TST ( 0.00667582946703267 ); GNF2_GSTM1 ( 0.00732286017628301 ); GNF2_LCAT ( 0.00942673488735472 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0034633 retinol transport ( ); GO:0048807 female genitalia morphogenesis ( ); GO:0060059 embryonic retina morphogenesis in camera-type eye ( ); GO:0060065 uterus development ( ); GO:0060068 vagina development ( ); GO:0034632 retinol transporter activity ( ); GO:0048646 anatomical structure formation ( ); GO:0030277 maintenance of gastrointestinal epithelium ( ); GO:0035112 genitalia morphogenesis ( ); GO:0060157 urinary bladder development ( ); GO:0009887 organ morphogenesis ( ); GO:0030540 female genitalia development ( ); GO:0051024 positive regulation of immunoglobulin secretion ( ); GO:0051023 regulation of immunoglobulin secretion ( ); GO:0060044 negative regulation of cardiac muscle cell proliferation ( ); GO:0060343 trabecula formation ( ); GO:0060347 heart trabecula formation ( ); GO:0048305 immunoglobulin secretion ( ); GO:0004969 histamine receptor activity ( ); GO:0032024 positive regulation of insulin secretion ( ); GO:0042572 retinol metabolic process ( ); GO:0060043 regulation of cardiac muscle cell proliferation ( ); ----------------GO-------------- GO:0034633 retinol transport ( 0.00120645453174484 ); GO:0048807 female genitalia morphogenesis ( 0.00120645453174484 ); GO:0060059 embryonic retina morphogenesis in camera-type eye ( 0.00120645453174484 ); GO:0060065 uterus development ( 0.00120645453174484 ); GO:0060068 vagina development ( 0.00120645453174484 ); GO:0034632 retinol transporter activity ( 0.00120645453174484 ); GO:0048646 anatomical structure formation ( 0.00239422651192996 ); GO:0030277 maintenance of gastrointestinal epithelium ( 0.00241151410801876 ); GO:0035112 genitalia morphogenesis ( 0.00241151410801876 ); GO:0060157 urinary bladder development ( 0.00241151410801876 ); GO:0009887 organ morphogenesis ( 0.00312572933656425 ); GO:0030540 female genitalia development ( 0.00361518027168106 ); GO:0051024 positive regulation of immunoglobulin secretion ( 0.00361518027168106 ); GO:0051023 regulation of immunoglobulin secretion ( 0.0048174545639631 ); GO:0060044 negative regulation of cardiac muscle cell proliferation ( 0.0048174545639631 ); GO:0060343 trabecula formation ( 0.0048174545639631 ); GO:0060347 heart trabecula formation ( 0.0048174545639631 ); GO:0048305 immunoglobulin secretion ( 0.00601833852446687 ); GO:0004969 histamine receptor activity ( 0.00721783369117057 ); GO:0032024 positive regulation of insulin secretion ( 0.00841594160042869 ); GO:0042572 retinol metabolic process ( 0.00841594160042869 ); GO:0060043 regulation of cardiac muscle cell proliferation ( 0.00841594160042869 ); ----------------KEGG-------------- ( 0.0494875647565171 ); ----------------CARTA-------------- ( 0.0191367388952013 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2980 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00569827740853914 ); ----------------C4-------------- module_426 ( 0.00426434730260134 ); module_121 ( 0.00605647187028615 ); ----------------C5-------------- ( 0.00786018959692495 ); ----------------GOSLIM-------------- GO:0048477 oogenesis ( 0.00137697907234962 ); GO:0007276 gamete generation ( 0.00137697907234962 ); GO:0019953 sexual reproduction ( 0.00137697907234962 ); GO:0007292 female gamete generation ( 0.00137697907234962 ); GO:0001555 oocyte growth ( 0.00137697907234962 ); GO:0030704 vitelline membrane formation ( 0.00137697907234962 ); GO:0048588 developmental cell growth ( 0.00137697907234962 ); GO:0008316 structural constituent of vitelline membrane ( 0.00137697907234962 ); GO:0031282 regulation of guanylate cyclase activity ( 0.00137697907234962 ); GO:0048601 oocyte morphogenesis ( 0.00137697907234962 ); GO:0022414 reproductive process ( 0.00137697907234962 ); GO:0000003 reproduction ( 0.00137697907234962 ); GO:0030823 regulation of cGMP metabolic process ( 0.00137697907234962 ); GO:0030826 regulation of cGMP biosynthetic process ( 0.00137697907234962 ); GO:0008048 calcium sensitive guanylate cyclase activator activity ( 0.00137697907234962 ); GO:0010853 cyclase activator activity ( 0.00137697907234962 ); GO:0030250 guanylate cyclase activator activity ( 0.00137697907234962 ); GO:0010851 cyclase regulator activity ( 0.00137697907234962 ); GO:0030249 guanylate cyclase regulator activity ( 0.00137697907234962 ); ----------------GO-------------- GO:0048477 oogenesis ( 0.000261547395282677 ); GO:0007276 gamete generation ( 0.000292812858244385 ); GO:0019953 sexual reproduction ( 0.00060090793619583 ); GO:0007292 female gamete generation ( 0.00105802069260869 ); GO:0001555 oocyte growth ( 0.00120645453174484 ); GO:0030704 vitelline membrane formation ( 0.00120645453174484 ); GO:0048588 developmental cell growth ( 0.00120645453174484 ); GO:0008316 structural constituent of vitelline membrane ( 0.00120645453174484 ); GO:0031282 regulation of guanylate cyclase activity ( 0.00241151410801876 ); GO:0048601 oocyte morphogenesis ( 0.00361518027168106 ); GO:0022414 reproductive process ( 0.00363174651574604 ); GO:0000003 reproduction ( 0.00372941913910369 ); GO:0030823 regulation of cGMP metabolic process ( 0.00601833852446687 ); GO:0030826 regulation of cGMP biosynthetic process ( 0.00601833852446687 ); GO:0008048 calcium sensitive guanylate cyclase activator activity ( 0.00601833852446687 ); GO:0010853 cyclase activator activity ( 0.00721783369117057 ); GO:0030250 guanylate cyclase activator activity ( 0.00721783369117057 ); GO:0010851 cyclase regulator activity ( 0.00841594160042869 ); GO:0030249 guanylate cyclase regulator activity ( 0.00841594160042869 ); ----------------KEGG-------------- hsa03440 Homologous recombination ( 0.0332584549362637 ); hsa04130 SNARE interactions in vesicular transport ( 0.0448775146498515 ); ----------------CARTA-------------- ( 0.0131945313333193 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0188672844235665 ); ----------------ARE-------------- ( ); ============================ group2719 ========================= ----------------C2-------------- REACTOME_PACKAGING_OF_TELOMERE_ENDS ( 1.84442299801701e-05 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING ( 3.13282796745876e-05 ); REACTOME_TELOMERE_MAINTENANCE ( 7.52830070282694e-05 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE ( 8.79122192885802e-05 ); REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION ( 0.000281423231829007 ); KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS ( 0.00036642245890532 ); REACTOME_INFLUENZA_LIFE_CYCLE ( 0.000437610744937399 ); REACTOME_TRANSCRIPTION ( 0.00122671387085299 ); REACTOME_PEPTIDE_CHAIN_ELONGATION ( 0.00385262148942395 ); REACTOME_VIRAL_MRNA_TRANSLATION ( 0.00385262148942395 ); KEGG_RIBOSOME ( 0.00412616360487954 ); REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS ( 0.00479854431899742 ); REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION ( 0.0054124565602251 ); REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS ( 0.0054124565602251 ); REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT ( 0.0059502154280247 ); REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT ( 0.00674252861001494 ); REACTOME_DIABETES_PATHWAYS ( 0.00744841348423904 ); REACTOME_TRANSLATION ( 0.00758024435527908 ); REACTOME_INSULIN_SYNTHESIS_AND_SECRETION ( 0.00872292404627319 ); REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION ( 0.00991131773973541 ); ----------------C3-------------- ( 0.0072157077535044 ); ----------------C4-------------- MORF_DEK ( 4.43670804615714e-06 ); MORF_EIF3S6 ( 5.9952662179885e-06 ); MORF_ANP32B ( 3.90973536321869e-05 ); MORF_UBE2I ( 7.60451772917271e-05 ); GCM_PSME1 ( 8.46343792365421e-05 ); module_32 ( 0.000108116176911567 ); MORF_RAN ( 0.000137915814702315 ); GCM_APEX1 ( 0.000210362105928428 ); GCM_NPM1 ( 0.000228423126303638 ); GCM_ACTG1 ( 0.000267498480399207 ); MORF_FBL ( 0.000325988926744248 ); MORF_ACTG1 ( 0.000419046957248269 ); MORF_NME2 ( 0.000527690156558479 ); MORF_NPM1 ( 0.000617074333509178 ); module_126 ( 0.000837888658269311 ); MORF_ACP1 ( 0.00100444661283199 ); module_87 ( 0.0010738288084085 ); MORF_AP2M1 ( 0.00128205821625634 ); MORF_SART1 ( 0.00167330091326523 ); GCM_MAP1B ( 0.00167330091326523 ); MORF_HDAC1 ( 0.00187580369675943 ); MORF_JUND ( 0.00218890185619098 ); GCM_TPT1 ( 0.00261884608376771 ); MORF_BUB3 ( 0.00279733983104402 ); module_83 ( 0.00415001685299723 ); module_151 ( 0.00415001685299723 ); GCM_CSNK2B ( 0.00440850317855631 ); module_114 ( 0.00484500484524865 ); MORF_RAD23A ( 0.00493112450864097 ); MORF_TPT1 ( 0.0054124565602251 ); MORF_ERH ( 0.0058407742748983 ); GNF2_EIF3S6 ( 0.00651149048246136 ); MORF_CDC10 ( 0.00795299477930185 ); MORF_EIF4A2 ( 0.00795299477930185 ); MORF_PRKAR1A ( 0.00925413539106283 ); ----------------C5-------------- TRANSLATION ( 0.000926353187796073 ); STRUCTURAL_CONSTITUENT_OF_RIBOSOME ( 0.00350168065888313 ); CELLULAR_BIOSYNTHETIC_PROCESS ( 0.00463374518912624 ); MACROMOLECULE_BIOSYNTHETIC_PROCESS ( 0.00471755846565159 ); NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 0.0087815480934953 ); MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS ( 0.00991131773973541 ); ----------------GOSLIM-------------- GO:0022625 cytosolic large ribosomal subunit ( 0.00993884657993712 ); GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process ( 0.00993884657993712 ); GO:0046080 dUTP metabolic process ( 0.00993884657993712 ); GO:0004170 dUTP diphosphatase activity ( 0.00993884657993712 ); GO:0015934 large ribosomal subunit ( 0.00993884657993712 ); GO:0006436 tryptophanyl-tRNA aminoacylation ( 0.00993884657993712 ); GO:0046125 pyrimidine deoxyribonucleoside metabolic process ( 0.00993884657993712 ); GO:0003878 ATP citrate synthase activity ( 0.00993884657993712 ); GO:0004776 succinate-CoA ligase (GDP-forming) activity ( 0.00993884657993712 ); GO:0004830 tryptophan-tRNA ligase activity ( 0.00993884657993712 ); GO:0022626 cytosolic ribosome ( 0.00993884657993712 ); GO:0009200 deoxyribonucleoside triphosphate metabolic process ( 0.00993884657993712 ); GO:0004775 succinate-CoA ligase (ADP-forming) activity ( 0.00993884657993712 ); GO:0009120 deoxyribonucleoside metabolic process ( 0.00993884657993712 ); GO:0004774 succinate-CoA ligase activity ( 0.00993884657993712 ); GO:0047429 nucleoside-triphosphate diphosphatase activity ( 0.00993884657993712 ); GO:0006414 translational elongation ( 0.00993884657993712 ); GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer ( 0.00993884657993712 ); GO:0033279 ribosomal subunit ( 0.00993884657993712 ); GO:0006412 translation ( 0.00993884657993712 ); GO:0016405 CoA-ligase activity ( 0.00993884657993712 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.00993884657993712 ); GO:0044445 cytosolic part ( 0.00993884657993712 ); ----------------GO-------------- GO:0022625 cytosolic large ribosomal subunit ( 0.000759544163330741 ); GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process ( 0.00110591665409943 ); GO:0046080 dUTP metabolic process ( 0.00110591665409943 ); GO:0004170 dUTP diphosphatase activity ( 0.00110591665409943 ); GO:0015934 large ribosomal subunit ( 0.00167330091326523 ); GO:0006436 tryptophanyl-tRNA aminoacylation ( 0.00221066579111973 ); GO:0046125 pyrimidine deoxyribonucleoside metabolic process ( 0.00221066579111973 ); GO:0003878 ATP citrate synthase activity ( 0.00221066579111973 ); GO:0004776 succinate-CoA ligase (GDP-forming) activity ( 0.00221066579111973 ); GO:0004830 tryptophan-tRNA ligase activity ( 0.00221066579111973 ); GO:0022626 cytosolic ribosome ( 0.00292581066885928 ); GO:0009200 deoxyribonucleoside triphosphate metabolic process ( 0.00331424858497587 ); GO:0004775 succinate-CoA ligase (ADP-forming) activity ( 0.00331424858497587 ); GO:0009120 deoxyribonucleoside metabolic process ( 0.00441666620846182 ); GO:0004774 succinate-CoA ligase activity ( 0.00441666620846182 ); GO:0047429 nucleoside-triphosphate diphosphatase activity ( 0.00441666620846182 ); GO:0006414 translational elongation ( 0.00530774900269066 ); GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer ( 0.0055179198332499 ); GO:0033279 ribosomal subunit ( 0.00628417466382816 ); GO:0006412 translation ( 0.00695833879327492 ); GO:0016405 CoA-ligase activity ( 0.00771693976783094 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.00881470841537724 ); GO:0044445 cytosolic part ( 0.00885438933335115 ); ----------------KEGG-------------- hsa05322 Systemic lupus erythematosus ( 0.000349882288349012 ); hsa03010 Ribosome ( 0.00284755397004702 ); hsa00020 Citrate cycle (TCA cycle) ( 0.0337457624702439 ); hsa00640 Propanoate metabolism ( 0.0380200351168235 ); hsa00970 Aminoacyl-tRNA biosynthesis ( 0.0443976199400919 ); ----------------CARTA-------------- bcellsurvivalpathway ( 0.00441666620846182 ); fbw7pathway ( 0.00661801062989475 ); npp1pathway ( 0.00771693976783094 ); p27pathway ( 0.00771693976783094 ); p35alzheimerspathway ( 0.0121010630821186 ); mitochondriapathway ( 0.0175552197719616 ); nthipathway ( 0.0197288241525042 ); raccycdpathway ( 0.0273003471013058 ); igf1mtorpathway ( 0.0283774254365063 ); mtorpathway ( 0.0454566191523285 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0118290340401296 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.014216898188055 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0184136333494508 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3101 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00842923976799893 ); ----------------C4-------------- module_303 ( 0.000402989807055146 ); MORF_SP3 ( 0.00254463794173993 ); module_40 ( 0.003587932964926 ); MORF_PRKAR1A ( 0.00925413539106283 ); ----------------C5-------------- SENSORY_PERCEPTION_OF_CHEMICAL_STIMULUS ( 0.000219167955595044 ); ELECTRON_CARRIER_ACTIVITY ( 0.00316661331196859 ); NUCLEOTIDE_SUGAR_METABOLIC_PROCESS ( 0.00991131773973541 ); ----------------GOSLIM-------------- GO:0009593 detection of chemical stimulus ( ); GO:0006065 UDP-glucuronate biosynthetic process ( ); GO:0015942 formate metabolic process ( ); GO:0046399 glucuronate biosynthetic process ( ); GO:0003979 UDP-glucose 6-dehydrogenase activity ( ); GO:0009055 electron carrier activity ( ); GO:0003032 detection of oxygen ( ); GO:0006011 UDP-glucose metabolic process ( ); GO:0046398 UDP-glucuronate metabolic process ( ); GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity ( ); GO:0032787 monocarboxylic acid metabolic process ( ); GO:0006063 uronic acid metabolic process ( ); GO:0019585 glucuronate metabolic process ( ); GO:0008339 MP kinase activity ( ); GO:0016882 cyclo-ligase activity ( ); GO:0051606 detection of stimulus ( ); GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste ( ); GO:0016174 NAD(P)H oxidase activity ( ); GO:0020037 heme binding ( ); GO:0046906 tetrapyrrole binding ( ); GO:0016909 SAP kinase activity ( ); GO:0050912 detection of chemical stimulus involved in sensory perception of taste ( ); GO:0050913 sensory perception of bitter taste ( ); GO:0004128 cytochrome-b5 reductase activity ( ); GO:0050907 detection of chemical stimulus involved in sensory perception ( ); GO:0008253 5'-nucleotidase activity ( ); GO:0016653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ( ); GO:0009396 folic acid and derivative biosynthetic process ( ); GO:0050664 oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor ( ); ----------------GO-------------- GO:0009593 detection of chemical stimulus ( 0.000344897456811545 ); GO:0006065 UDP-glucuronate biosynthetic process ( 0.00110591665409943 ); GO:0015942 formate metabolic process ( 0.00110591665409943 ); GO:0046399 glucuronate biosynthetic process ( 0.00110591665409943 ); GO:0003979 UDP-glucose 6-dehydrogenase activity ( 0.00110591665409943 ); GO:0009055 electron carrier activity ( 0.00137776359793965 ); GO:0003032 detection of oxygen ( 0.00221066579111973 ); GO:0006011 UDP-glucose metabolic process ( 0.00221066579111973 ); GO:0046398 UDP-glucuronate metabolic process ( 0.00221066579111973 ); GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity ( 0.00221066579111973 ); GO:0032787 monocarboxylic acid metabolic process ( 0.00239002425618746 ); GO:0006063 uronic acid metabolic process ( 0.00331424858497587 ); GO:0019585 glucuronate metabolic process ( 0.00331424858497587 ); GO:0008339 MP kinase activity ( 0.00331424858497587 ); GO:0016882 cyclo-ligase activity ( 0.00331424858497587 ); GO:0051606 detection of stimulus ( 0.0054124565602251 ); GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste ( 0.0055179198332499 ); GO:0016174 NAD(P)H oxidase activity ( 0.0055179198332499 ); GO:0020037 heme binding ( 0.00651149048246136 ); GO:0046906 tetrapyrrole binding ( 0.00651149048246136 ); GO:0016909 SAP kinase activity ( 0.00661801062989475 ); GO:0050912 detection of chemical stimulus involved in sensory perception of taste ( 0.00771693976783094 ); GO:0050913 sensory perception of bitter taste ( 0.00771693976783094 ); GO:0004128 cytochrome-b5 reductase activity ( 0.00771693976783094 ); GO:0050907 detection of chemical stimulus involved in sensory perception ( 0.00881470841537724 ); GO:0008253 5'-nucleotidase activity ( 0.00881470841537724 ); GO:0016653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ( 0.00881470841537724 ); GO:0009396 folic acid and derivative biosynthetic process ( 0.00991131773973541 ); GO:0050664 oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor ( 0.00991131773973541 ); ----------------KEGG-------------- hsa00520 Nucleotide sugars metabolism ( 0.00661801062989475 ); hsa00053 Ascorbate and aldarate metabolism ( 0.00991131773973541 ); hsa00670 One carbon pool by folate ( 0.0175552197719616 ); hsa00040 Pentose and glucuronate interconversions ( 0.018642596396453 ); hsa00760 Nicotinate and nicotinamide metabolism ( 0.0262221291155262 ); hsa00500 Starch and sucrose metabolism ( 0.0465144980691911 ); ----------------CARTA-------------- ( 0.0142861851103071 ); ----------------RBP-------------- IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.00384722992599639 ); ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 0.0283030018482727 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3118 ========================= ----------------C2-------------- REACTOME_HIV_INFECTION ( 0.00102055037686578 ); REACTOME_TOLL_LIKE_RECEPTOR_3_CASCADE ( 0.00173411471450933 ); KEGG_VEGF_SIGNALING_PATHWAY ( 0.00308534245401069 ); KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY ( 0.00308534245401069 ); KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY ( 0.00333215441079344 ); REACTOME_TOLL_RECEPTOR_CASCADES ( 0.00376340546984528 ); KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY ( 0.00530774900269066 ); REACTOME_INNATE_IMMUNITY_SIGNALING ( 0.0058407742748983 ); REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS ( 0.00758024435527908 ); KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY ( 0.00952507180813345 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_MTA1 ( 0.000147424530000968 ); GNF2_INPP5D ( 0.00080120451388376 ); GCM_PFN1 ( 0.00127699890050924 ); GNF2_CD53 ( 0.00161353256106903 ); GCM_CBFB ( 0.00205378955127205 ); GCM_PSME1 ( 0.00333215441079344 ); MORF_PRDX3 ( 0.00350168065888313 ); module_151 ( 0.00415001685299723 ); GCM_CSNK2B ( 0.00440850317855631 ); module_114 ( 0.00484500484524865 ); GCM_APEX1 ( 0.0060605972226804 ); GCM_NPM1 ( 0.00639736628135199 ); GCM_ACTG1 ( 0.00709603009671127 ); MORF_MAP2K2 ( 0.00820603195559869 ); ----------------C5-------------- ( 0.00520399426271682 ); ----------------GOSLIM-------------- GO:0044444 cytoplasmic part ( 0.00176710486611734 ); GO:0005737 cytoplasm ( 0.00176710486611734 ); GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration ( 0.00176710486611734 ); GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core ( 0.00176710486611734 ); GO:0045267 proton-transporting ATP synthase, catalytic core ( 0.00176710486611734 ); GO:0016206 catechol O-methyltransferase activity ( 0.00176710486611734 ); GO:0015760 glucose-6-phosphate transport ( 0.00176710486611734 ); GO:0042420 dopamine catabolic process ( 0.00176710486611734 ); GO:0042424 catecholamine catabolic process ( 0.00176710486611734 ); GO:0008537 proteasome activator complex ( 0.00176710486611734 ); GO:0004346 glucose-6-phosphatase activity ( 0.00176710486611734 ); GO:0010310 regulation of hydrogen peroxide metabolic process ( 0.00176710486611734 ); GO:0004032 aldehyde reductase activity ( 0.00176710486611734 ); GO:0008538 proteasome activator activity ( 0.00176710486611734 ); GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism ( 0.00176710486611734 ); GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ( 0.00176710486611734 ); GO:0042135 neurotransmitter catabolic process ( 0.00176710486611734 ); GO:0060263 regulation of respiratory burst ( 0.00176710486611734 ); GO:0080010 regulation of oxygen and reactive oxygen species metabolic process ( 0.00176710486611734 ); GO:0010860 proteasome regulator activity ( 0.00176710486611734 ); GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) ( 0.00176710486611734 ); GO:0008171 O-methyltransferase activity ( 0.00176710486611734 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00176710486611734 ); GO:0043227 membrane-bounded organelle ( 0.00176710486611734 ); ----------------GO-------------- GO:0044444 cytoplasmic part ( 0.00045870699007647 ); GO:0005737 cytoplasm ( 0.00105946945152127 ); GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration ( 0.00110591665409943 ); GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core ( 0.00110591665409943 ); GO:0045267 proton-transporting ATP synthase, catalytic core ( 0.00110591665409943 ); GO:0016206 catechol O-methyltransferase activity ( 0.00110591665409943 ); GO:0015760 glucose-6-phosphate transport ( 0.00331424858497587 ); GO:0042420 dopamine catabolic process ( 0.00331424858497587 ); GO:0042424 catecholamine catabolic process ( 0.00331424858497587 ); GO:0008537 proteasome activator complex ( 0.00331424858497587 ); GO:0004346 glucose-6-phosphatase activity ( 0.00331424858497587 ); GO:0010310 regulation of hydrogen peroxide metabolic process ( 0.00441666620846182 ); GO:0004032 aldehyde reductase activity ( 0.00441666620846182 ); GO:0008538 proteasome activator activity ( 0.00441666620846182 ); GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism ( 0.00441666620846182 ); GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ( 0.0055179198332499 ); GO:0042135 neurotransmitter catabolic process ( 0.00661801062989475 ); GO:0060263 regulation of respiratory burst ( 0.00661801062989475 ); GO:0080010 regulation of oxygen and reactive oxygen species metabolic process ( 0.00661801062989475 ); GO:0010860 proteasome regulator activity ( 0.00661801062989475 ); GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) ( 0.00771693976783094 ); GO:0008171 O-methyltransferase activity ( 0.00771693976783094 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00983878009185244 ); GO:0043227 membrane-bounded organelle ( 0.0098787618680728 ); ----------------KEGG-------------- hsa04370 VEGF signaling pathway ( 0.00292581066885928 ); hsa04664 Fc epsilon RI signaling pathway ( 0.00316661331196859 ); hsa04620 Toll-like receptor signaling pathway ( 0.0054124565602251 ); hsa04650 Natural killer cell mediated cytotoxicity ( 0.00911999695308285 ); hsa04810 Regulation of actin cytoskeleton ( 0.0223010800439452 ); hsa05216 Thyroid cancer ( 0.0316018340059504 ); hsa04010 MAPK signaling pathway ( 0.0342750064427558 ); hsa03022 Basal transcription factors ( 0.0358851598000928 ); hsa05219 Bladder cancer ( 0.0454566191523285 ); hsa03050 Proteasome ( 0.0475712578194422 ); hsa00350 Tyrosine metabolism ( 0.0486268995307615 ); ----------------CARTA-------------- g1pathway ( 0.000176724543579161 ); vobesitypathway ( 0.00661801062989475 ); rhodopsinpathway ( 0.0121010630821186 ); no2il12pathway ( 0.0131942014289747 ); gabapathway ( 0.0175552197719616 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00688988929089916 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0487390245408255 ); ----------------immu-------------- ( 0.00911999695308285 ); ----------------ARE-------------- ( ); ============================ group3185 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$MTF1_Q4 ( 4.74450854405533e-05 ); V$STAT3_02 ( 0.000234659421446226 ); V$FOXJ2_01 ( 0.000538375059510696 ); GGAANCGGAANY_UNKNOWN ( 0.00333215441079344 ); TGCGCANK_UNKNOWN ( 0.0070655140528663 ); RTTTNNNYTGGM_UNKNOWN ( 0.00745781686784492 ); V$NCX_01 ( 0.00872292404627319 ); ----------------C4-------------- MORF_PRKACA ( 0.0058407742748983 ); module_152 ( 0.00770358448768464 ); ----------------C5-------------- SIGNAL_TRANSDUCTION ( 0.0062121301271684 ); RIBONUCLEOPROTEIN_COMPLEX ( 0.00885438933335115 ); ----------------GOSLIM-------------- GO:0050806 positive regulation of synaptic transmission ( ); GO:0051971 positive regulation of transmission of nerve impulse ( ); GO:0031646 positive regulation of neurological system process ( ); GO:0051240 positive regulation of multicellular organismal process ( ); GO:0015758 glucose transport ( ); GO:0008645 hexose transport ( ); GO:0015749 monosaccharide transport ( ); GO:0002090 regulation of receptor internalization ( ); GO:0002092 positive regulation of receptor internalization ( ); GO:0007559 histolysis ( ); GO:0010533 regulation of activation of Janus kinase activity ( ); GO:0010534 regulation of activation of JAK2 kinase activity ( ); GO:0010535 positive regulation of activation of JAK2 kinase activity ( ); GO:0010536 positive regulation of activation of Janus kinase activity ( ); GO:0010702 regulation of histolysis ( ); GO:0010703 negative regulation of histolysis ( ); GO:0010710 regulation of collagen catabolic process ( ); GO:0010711 negative regulation of collagen catabolic process ( ); GO:0010715 regulation of extracellular matrix disassembly ( ); GO:0010716 negative regulation of extracellular matrix disassembly ( ); GO:0016271 tissue death ( ); GO:0031547 brain-derived neurotrophic factor receptor signaling pathway ( ); GO:0060309 elastin catabolic process ( ); GO:0060310 regulation of elastin catabolic process ( ); GO:0060311 negative regulation of elastin catabolic process ( ); GO:0060312 regulation of blood vessel remodeling ( ); GO:0060313 negative regulation of blood vessel remodeling ( ); GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity ( ); GO:0048403 brain-derived neurotrophic factor binding ( ); GO:0070186 growth hormone activity ( ); GO:0010647 positive regulation of cell communication ( ); GO:0008643 carbohydrate transport ( ); GO:0050804 regulation of synaptic transmission ( ); GO:0010713 negative regulation of collagen metabolic process ( ); GO:0022617 extracellular matrix disassembly ( ); GO:0044252 negative regulation of multicellular organismal metabolic process ( ); GO:0051541 elastin metabolic process ( ); GO:0051968 positive regulation of synaptic transmission, glutamatergic ( ); GO:0060076 excitatory synapse ( ); GO:0001632 leukotriene B4 receptor activity ( ); GO:0005148 prolactin receptor binding ( ); GO:0051969 regulation of transmission of nerve impulse ( ); GO:0045761 regulation of adenylate cyclase activity ( ); GO:0051049 regulation of transport ( ); GO:0031644 regulation of neurological system process ( ); GO:0031279 regulation of cyclase activity ( ); GO:0051339 regulation of lyase activity ( ); GO:0030817 regulation of cAMP biosynthetic process ( ); GO:0030814 regulation of cAMP metabolic process ( ); GO:0030802 regulation of cyclic nucleotide biosynthetic process ( ); GO:0030808 regulation of nucleotide biosynthetic process ( ); GO:0002036 regulation of L-glutamate transport ( ); GO:0002037 negative regulation of L-glutamate transport ( ); GO:0032891 negative regulation of organic acid transport ( ); GO:0042976 activation of Janus kinase activity ( ); GO:0042977 activation of JAK2 kinase activity ( ); GO:0046548 retinal rod cell development ( ); GO:0050773 regulation of dendrite development ( ); GO:0051953 negative regulation of amine transport ( ); GO:0051956 negative regulation of amino acid transport ( ); GO:0048786 presynaptic active zone ( ); GO:0005030 neurotrophin receptor activity ( ); GO:0043295 glutathione binding ( ); GO:0030799 regulation of cyclic nucleotide metabolic process ( ); GO:0006140 regulation of nucleotide metabolic process ( ); GO:0006171 cAMP biosynthetic process ( ); GO:0051239 regulation of multicellular organismal process ( ); GO:0046058 cAMP metabolic process ( ); GO:0051955 regulation of amino acid transport ( ); GO:0043195 terminal button ( ); GO:0004974 leukotriene receptor activity ( ); GO:0009190 cyclic nucleotide biosynthetic process ( ); GO:0050790 regulation of catalytic activity ( ); GO:0014047 glutamate secretion ( ); GO:0043206 fibril organization ( ); GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway ( ); GO:0048535 lymph node development ( ); GO:0005131 growth hormone receptor binding ( ); GO:0009187 cyclic nucleotide metabolic process ( ); GO:0010712 regulation of collagen metabolic process ( ); GO:0032890 regulation of organic acid transport ( ); GO:0046325 negative regulation of glucose import ( ); GO:0048260 positive regulation of receptor-mediated endocytosis ( ); GO:0051546 keratinocyte migration ( ); GO:0032879 regulation of localization ( ); GO:0051050 positive regulation of transport ( ); GO:0065009 regulation of molecular function ( ); GO:0010829 negative regulation of glucose transport ( ); GO:0014066 regulation of phosphoinositide 3-kinase cascade ( ); GO:0014068 positive regulation of phosphoinositide 3-kinase cascade ( ); GO:0031330 negative regulation of cellular catabolic process ( ); GO:0031623 receptor internalization ( ); GO:0051966 regulation of synaptic transmission, glutamatergic ( ); GO:0060396 growth hormone receptor signaling pathway ( ); GO:0060416 response to growth hormone stimulus ( ); GO:0043525 positive regulation of neuron apoptosis ( ); GO:0033267 axon part ( ); GO:0043121 neurotrophin binding ( ); GO:0016043 cellular component organization ( ); GO:0010740 positive regulation of protein kinase cascade ( ); GO:0032355 response to estradiol stimulus ( ); GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein ( ); GO:0043567 regulation of insulin-like growth factor receptor signaling pathway ( ); GO:0044246 regulation of multicellular organismal metabolic process ( ); GO:0004602 glutathione peroxidase activity ( ); ----------------GO-------------- GO:0050806 positive regulation of synaptic transmission ( 9.03972529903781e-05 ); GO:0051971 positive regulation of transmission of nerve impulse ( 0.000105392803543882 ); GO:0031646 positive regulation of neurological system process ( 0.000121525610635201 ); GO:0051240 positive regulation of multicellular organismal process ( 0.000400998484384147 ); GO:0015758 glucose transport ( 0.000718968898672834 ); GO:0008645 hexose transport ( 0.000759544163330741 ); GO:0015749 monosaccharide transport ( 0.000759544163330741 ); GO:0002090 regulation of receptor internalization ( 0.00110591665409943 ); GO:0002092 positive regulation of receptor internalization ( 0.00110591665409943 ); GO:0007559 histolysis ( 0.00110591665409943 ); GO:0010533 regulation of activation of Janus kinase activity ( 0.00110591665409943 ); GO:0010534 regulation of activation of JAK2 kinase activity ( 0.00110591665409943 ); GO:0010535 positive regulation of activation of JAK2 kinase activity ( 0.00110591665409943 ); GO:0010536 positive regulation of activation of Janus kinase activity ( 0.00110591665409943 ); GO:0010702 regulation of histolysis ( 0.00110591665409943 ); GO:0010703 negative regulation of histolysis ( 0.00110591665409943 ); GO:0010710 regulation of collagen catabolic process ( 0.00110591665409943 ); GO:0010711 negative regulation of collagen catabolic process ( 0.00110591665409943 ); GO:0010715 regulation of extracellular matrix disassembly ( 0.00110591665409943 ); GO:0010716 negative regulation of extracellular matrix disassembly ( 0.00110591665409943 ); GO:0016271 tissue death ( 0.00110591665409943 ); GO:0031547 brain-derived neurotrophic factor receptor signaling pathway ( 0.00110591665409943 ); GO:0060309 elastin catabolic process ( 0.00110591665409943 ); GO:0060310 regulation of elastin catabolic process ( 0.00110591665409943 ); GO:0060311 negative regulation of elastin catabolic process ( 0.00110591665409943 ); GO:0060312 regulation of blood vessel remodeling ( 0.00110591665409943 ); GO:0060313 negative regulation of blood vessel remodeling ( 0.00110591665409943 ); GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity ( 0.00110591665409943 ); GO:0048403 brain-derived neurotrophic factor binding ( 0.00110591665409943 ); GO:0070186 growth hormone activity ( 0.00110591665409943 ); GO:0010647 positive regulation of cell communication ( 0.00178218831465529 ); GO:0008643 carbohydrate transport ( 0.00205378955127205 ); GO:0050804 regulation of synaptic transmission ( 0.00205378955127205 ); GO:0010713 negative regulation of collagen metabolic process ( 0.00221066579111973 ); GO:0022617 extracellular matrix disassembly ( 0.00221066579111973 ); GO:0044252 negative regulation of multicellular organismal metabolic process ( 0.00221066579111973 ); GO:0051541 elastin metabolic process ( 0.00221066579111973 ); GO:0051968 positive regulation of synaptic transmission, glutamatergic ( 0.00221066579111973 ); GO:0060076 excitatory synapse ( 0.00221066579111973 ); GO:0001632 leukotriene B4 receptor activity ( 0.00221066579111973 ); GO:0005148 prolactin receptor binding ( 0.00221066579111973 ); GO:0051969 regulation of transmission of nerve impulse ( 0.00232812681270813 ); GO:0045761 regulation of adenylate cyclase activity ( 0.00247144725916427 ); GO:0051049 regulation of transport ( 0.00247395732354804 ); GO:0031644 regulation of neurological system process ( 0.00254463794173993 ); GO:0031279 regulation of cyclase activity ( 0.00261884608376771 ); GO:0051339 regulation of lyase activity ( 0.00277030622447287 ); GO:0030817 regulation of cAMP biosynthetic process ( 0.00284755397004702 ); GO:0030814 regulation of cAMP metabolic process ( 0.00300507420209116 ); GO:0030802 regulation of cyclic nucleotide biosynthetic process ( 0.00324888466639455 ); GO:0030808 regulation of nucleotide biosynthetic process ( 0.00324888466639455 ); GO:0002036 regulation of L-glutamate transport ( 0.00331424858497587 ); GO:0002037 negative regulation of L-glutamate transport ( 0.00331424858497587 ); GO:0032891 negative regulation of organic acid transport ( 0.00331424858497587 ); GO:0042976 activation of Janus kinase activity ( 0.00331424858497587 ); GO:0042977 activation of JAK2 kinase activity ( 0.00331424858497587 ); GO:0046548 retinal rod cell development ( 0.00331424858497587 ); GO:0050773 regulation of dendrite development ( 0.00331424858497587 ); GO:0051953 negative regulation of amine transport ( 0.00331424858497587 ); GO:0051956 negative regulation of amino acid transport ( 0.00331424858497587 ); GO:0048786 presynaptic active zone ( 0.00331424858497587 ); GO:0005030 neurotrophin receptor activity ( 0.00331424858497587 ); GO:0043295 glutathione binding ( 0.00331424858497587 ); GO:0030799 regulation of cyclic nucleotide metabolic process ( 0.00341642044174162 ); GO:0006140 regulation of nucleotide metabolic process ( 0.00367517526563847 ); GO:0006171 cAMP biosynthetic process ( 0.00367517526563847 ); GO:0051239 regulation of multicellular organismal process ( 0.00375107523621888 ); GO:0046058 cAMP metabolic process ( 0.00403400263744841 ); GO:0051955 regulation of amino acid transport ( 0.00441666620846182 ); GO:0043195 terminal button ( 0.00441666620846182 ); GO:0004974 leukotriene receptor activity ( 0.00441666620846182 ); GO:0009190 cyclic nucleotide biosynthetic process ( 0.00499935139757328 ); GO:0050790 regulation of catalytic activity ( 0.00502880046409625 ); GO:0014047 glutamate secretion ( 0.0055179198332499 ); GO:0043206 fibril organization ( 0.0055179198332499 ); GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway ( 0.0055179198332499 ); GO:0048535 lymph node development ( 0.0055179198332499 ); GO:0005131 growth hormone receptor binding ( 0.0055179198332499 ); GO:0009187 cyclic nucleotide metabolic process ( 0.00562472198379345 ); GO:0010712 regulation of collagen metabolic process ( 0.00661801062989475 ); GO:0032890 regulation of organic acid transport ( 0.00661801062989475 ); GO:0046325 negative regulation of glucose import ( 0.00661801062989475 ); GO:0048260 positive regulation of receptor-mediated endocytosis ( 0.00661801062989475 ); GO:0051546 keratinocyte migration ( 0.00661801062989475 ); GO:0032879 regulation of localization ( 0.0071194715623102 ); GO:0051050 positive regulation of transport ( 0.00733630400605528 ); GO:0065009 regulation of molecular function ( 0.0076171352483128 ); GO:0010829 negative regulation of glucose transport ( 0.00771693976783094 ); GO:0014066 regulation of phosphoinositide 3-kinase cascade ( 0.00771693976783094 ); GO:0014068 positive regulation of phosphoinositide 3-kinase cascade ( 0.00771693976783094 ); GO:0031330 negative regulation of cellular catabolic process ( 0.00771693976783094 ); GO:0031623 receptor internalization ( 0.00771693976783094 ); GO:0051966 regulation of synaptic transmission, glutamatergic ( 0.00771693976783094 ); GO:0060396 growth hormone receptor signaling pathway ( 0.00771693976783094 ); GO:0060416 response to growth hormone stimulus ( 0.00771693976783094 ); GO:0043525 positive regulation of neuron apoptosis ( 0.00881470841537724 ); GO:0033267 axon part ( 0.00881470841537724 ); GO:0043121 neurotrophin binding ( 0.00881470841537724 ); GO:0016043 cellular component organization ( 0.00922412795896025 ); GO:0010740 positive regulation of protein kinase cascade ( 0.00938916098946352 ); GO:0032355 response to estradiol stimulus ( 0.00991131773973541 ); GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein ( 0.00991131773973541 ); GO:0043567 regulation of insulin-like growth factor receptor signaling pathway ( 0.00991131773973541 ); GO:0044246 regulation of multicellular organismal metabolic process ( 0.00991131773973541 ); GO:0004602 glutathione peroxidase activity ( 0.00991131773973541 ); ----------------KEGG-------------- hsa04080 Neuroactive ligand-receptor interaction ( 0.0317135488068107 ); hsa04060 Cytokine-cytokine receptor interaction ( 0.0319430876798805 ); hsa04940 Type I diabetes mellitus ( 0.0433374993026393 ); ----------------CARTA-------------- pparpathway ( 0.00991131773973541 ); ptc1pathway ( 0.00991131773973541 ); il10pathway ( 0.0262221291155262 ); ----------------RBP-------------- AGO2_PAR-CLIP_(Kishore_2011) ( 0.00224820117393945 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00314772579474682 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0150352848292822 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0211769478461968 ); ----------------immu-------------- ( 0.0119622783342216 ); ----------------ARE-------------- ( 0.0243274511397336 ); ============================ group2508 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00296093492590371 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0043438 acetoacetic acid metabolic process ( ); GO:0043437 butanoic acid metabolic process ( ); GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ( ); GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen ( ); GO:0006583 melanin biosynthetic process from tyrosine ( ); GO:0035019 somatic stem cell maintenance ( ); GO:0046473 phosphatidic acid metabolic process ( ); GO:0034374 low-density lipoprotein particle remodeling ( ); GO:0042438 melanin biosynthetic process ( ); GO:0047498 calcium-dependent phospholipase A2 activity ( ); GO:0006582 melanin metabolic process ( ); GO:0032438 melanosome organization ( ); GO:0048753 pigment granule organization ( ); GO:0033162 melanosome membrane ( ); GO:0045009 chitosome ( ); GO:0007342 fusion of sperm to egg plasma membrane ( ); ----------------GO-------------- GO:0043438 acetoacetic acid metabolic process ( 0.00105564771527678 ); GO:0043437 butanoic acid metabolic process ( 0.00211023405139066 ); GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ( 0.00211023405139066 ); GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen ( 0.00316376002217755 ); GO:0006583 melanin biosynthetic process from tyrosine ( 0.00526763491852522 ); GO:0035019 somatic stem cell maintenance ( 0.00526763491852522 ); GO:0046473 phosphatidic acid metabolic process ( 0.00526763491852522 ); GO:0034374 low-density lipoprotein particle remodeling ( 0.00631798586717325 ); GO:0042438 melanin biosynthetic process ( 0.00631798586717325 ); GO:0047498 calcium-dependent phospholipase A2 activity ( 0.00631798586717325 ); GO:0006582 melanin metabolic process ( 0.00736728049666979 ); GO:0032438 melanosome organization ( 0.00736728049666979 ); GO:0048753 pigment granule organization ( 0.00841551981626987 ); GO:0033162 melanosome membrane ( 0.00841551981626987 ); GO:0045009 chitosome ( 0.00841551981626987 ); GO:0007342 fusion of sperm to egg plasma membrane ( 0.00946270483431655 ); ----------------KEGG-------------- hsa00592 alpha-Linolenic acid metabolism ( 0.0167635640264117 ); hsa00534 Heparan sulfate biosynthesis ( 0.0198767896130104 ); hsa00591 Linoleic acid metabolism ( 0.0291602373207401 ); hsa04010 MAPK signaling pathway ( 0.03143039220992 ); hsa00565 Ether lipid metabolism ( 0.0332592786128635 ); hsa00350 Tyrosine metabolism ( 0.0464676323939728 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2987 ========================= ----------------C2-------------- ( ); ----------------C3-------------- AAGTCCA,MIR-422B,MIR-422A ( 0.00146939986476133 ); YAATNRNNNYNATT_UNKNOWN ( 0.00327036765631363 ); CCAGGGG,MIR-331 ( 0.00334999941752836 ); AACTGAC,MIR-223 ( 0.00343053697215594 ); V$DR3_Q4 ( 0.00474606751281482 ); TGCTGAY_UNKNOWN ( 0.00883131278775693 ); ----------------C4-------------- ( 0.000583426906807939 ); ----------------C5-------------- AMINO_ACID_AND_DERIVATIVE_METABOLIC_PROCESS ( 0.00474606751281482 ); AMINE_METABOLIC_PROCESS ( 0.00907527728131249 ); ----------------GOSLIM-------------- GO:0046203 spermidine catabolic process ( ); GO:0050983 spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase ( ); GO:0000125 PCAF complex ( ); GO:0008907 integrase activity ( ); GO:0034038 deoxyhypusine synthase activity ( ); GO:0006598 polyamine catabolic process ( ); GO:0032237 activation of store-operated calcium channel activity ( ); GO:0008525 phosphatidylcholine transmembrane transporter activity ( ); GO:0008216 spermidine metabolic process ( ); GO:0032236 positive regulation of calcium ion transport via store-operated calcium channel activity ( ); GO:0008076 voltage-gated potassium channel complex ( ); GO:0034705 potassium channel complex ( ); GO:0042578 phosphoric ester hydrolase activity ( ); GO:0008612 peptidyl-lysine modification to hypusine ( ); GO:0046516 hypusine metabolic process ( ); GO:0008113 peptide-methionine-(S)-S-oxide reductase activity ( ); GO:0005249 voltage-gated potassium channel activity ( ); GO:0032234 regulation of calcium ion transport via store-operated calcium channel activity ( ); GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ( ); GO:0008526 phosphatidylinositol transporter activity ( ); GO:0034595 phosphoinositide 5-phosphatase activity ( ); GO:0032411 positive regulation of transporter activity ( ); GO:0032414 positive regulation of ion transmembrane transporter activity ( ); GO:0035267 NuA4 histone acetyltransferase complex ( ); GO:0034703 cation channel complex ( ); GO:0005267 potassium channel activity ( ); GO:0043189 H4/H2A histone acetyltransferase complex ( ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( ); GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor ( ); GO:0046030 inositol trisphosphate phosphatase activity ( ); GO:0034593 phosphatidylinositol bisphosphate phosphatase activity ( ); GO:0034702 ion channel complex ( ); GO:0022843 voltage-gated cation channel activity ( ); GO:0005513 detection of calcium ion ( ); GO:0006595 polyamine metabolic process ( ); ----------------GO-------------- GO:0046203 spermidine catabolic process ( 0.00105564771527678 ); GO:0050983 spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase ( 0.00105564771527678 ); GO:0000125 PCAF complex ( 0.00105564771527678 ); GO:0008907 integrase activity ( 0.00105564771527678 ); GO:0034038 deoxyhypusine synthase activity ( 0.00105564771527678 ); GO:0006598 polyamine catabolic process ( 0.00211023405139066 ); GO:0032237 activation of store-operated calcium channel activity ( 0.00211023405139066 ); GO:0008525 phosphatidylcholine transmembrane transporter activity ( 0.00211023405139066 ); GO:0008216 spermidine metabolic process ( 0.00316376002217755 ); GO:0032236 positive regulation of calcium ion transport via store-operated calcium channel activity ( 0.00316376002217755 ); GO:0008076 voltage-gated potassium channel complex ( 0.00327036765631363 ); GO:0034705 potassium channel complex ( 0.00327036765631363 ); GO:0042578 phosphoric ester hydrolase activity ( 0.00404809182976771 ); GO:0008612 peptidyl-lysine modification to hypusine ( 0.00421622664055576 ); GO:0046516 hypusine metabolic process ( 0.00421622664055576 ); GO:0008113 peptide-methionine-(S)-S-oxide reductase activity ( 0.00421622664055576 ); GO:0005249 voltage-gated potassium channel activity ( 0.00428533317948915 ); GO:0032234 regulation of calcium ion transport via store-operated calcium channel activity ( 0.00526763491852522 ); GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ( 0.00526763491852522 ); GO:0008526 phosphatidylinositol transporter activity ( 0.00526763491852522 ); GO:0034595 phosphoinositide 5-phosphatase activity ( 0.00526763491852522 ); GO:0032411 positive regulation of transporter activity ( 0.00631798586717325 ); GO:0032414 positive regulation of ion transmembrane transporter activity ( 0.00631798586717325 ); GO:0035267 NuA4 histone acetyltransferase complex ( 0.00631798586717325 ); GO:0034703 cation channel complex ( 0.00669495120839834 ); GO:0005267 potassium channel activity ( 0.00691802294597615 ); GO:0043189 H4/H2A histone acetyltransferase complex ( 0.00736728049666979 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.00736728049666979 ); GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor ( 0.00736728049666979 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.00736728049666979 ); GO:0034593 phosphatidylinositol bisphosphate phosphatase activity ( 0.00841551981626987 ); GO:0034702 ion channel complex ( 0.00844930476318295 ); GO:0022843 voltage-gated cation channel activity ( 0.00869725136714388 ); GO:0005513 detection of calcium ion ( 0.00946270483431655 ); GO:0006595 polyamine metabolic process ( 0.00946270483431655 ); ----------------KEGG-------------- ( 0.0494912127466919 ); ----------------CARTA-------------- ( 0.0167635640264117 ); ----------------RBP-------------- TDP-43_iCLIP_(Tollervey_2011) ( 0.000559520168800772 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00395047206176691 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3016 ========================= ----------------C2-------------- ( 0.00513045277028997 ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_FGR ( 0.000484513005130878 ); GNF2_ITGB2 ( 0.00146939986476133 ); GNF2_TNFRSF1B ( 0.00181057944644698 ); GNF2_HCK ( 0.00384674822258078 ); GNF2_CASP1 ( 0.00465215941173526 ); ----------------C5-------------- ( 0.00946270483431655 ); ----------------GOSLIM-------------- GO:0021932 hindbrain radial glia guided cell migration ( ); GO:0021933 radial glia guided migration of granule cell ( ); GO:0048668 collateral sprouting ( ); GO:0048670 regulation of collateral sprouting ( ); GO:0048671 negative regulation of collateral sprouting ( ); GO:0019103 pyrimidine nucleotide binding ( ); GO:0021535 cell migration in hindbrain ( ); GO:0021681 cerebellar granular layer development ( ); GO:0021683 cerebellar granular layer morphogenesis ( ); GO:0021684 cerebellar granular layer formation ( ); GO:0021707 cerebellar granule cell differentiation ( ); GO:0010506 regulation of autophagy ( ); GO:0051001 negative regulation of nitric-oxide synthase activity ( ); GO:0051386 regulation of nerve growth factor receptor signaling pathway ( ); GO:0032769 negative regulation of monooxygenase activity ( ); GO:0004430 1-phosphatidylinositol 4-kinase activity ( ); GO:0000012 single strand break repair ( ); GO:0007094 mitotic cell cycle spindle assembly checkpoint ( ); GO:0031577 spindle checkpoint ( ); GO:0050771 negative regulation of axonogenesis ( ); GO:0051354 negative regulation of oxidoreductase activity ( ); GO:0009223 pyrimidine deoxyribonucleotide catabolic process ( ); GO:0021697 cerebellar cortex formation ( ); GO:0031345 negative regulation of cell projection organization ( ); GO:0031623 receptor internalization ( ); GO:0004703 G-protein coupled receptor kinase activity ( ); GO:0006244 pyrimidine nucleotide catabolic process ( ); GO:0006661 phosphatidylinositol biosynthetic process ( ); GO:0021533 cell differentiation in hindbrain ( ); GO:0008253 5'-nucleotidase activity ( ); GO:0021696 cerebellar cortex morphogenesis ( ); GO:0042994 cytoplasmic sequestering of transcription factor ( ); GO:0048011 nerve growth factor receptor signaling pathway ( ); ----------------GO-------------- GO:0021932 hindbrain radial glia guided cell migration ( 0.00105564771527678 ); GO:0021933 radial glia guided migration of granule cell ( 0.00105564771527678 ); GO:0048668 collateral sprouting ( 0.00105564771527678 ); GO:0048670 regulation of collateral sprouting ( 0.00105564771527678 ); GO:0048671 negative regulation of collateral sprouting ( 0.00105564771527678 ); GO:0019103 pyrimidine nucleotide binding ( 0.00105564771527678 ); GO:0021535 cell migration in hindbrain ( 0.00211023405139066 ); GO:0021681 cerebellar granular layer development ( 0.00211023405139066 ); GO:0021683 cerebellar granular layer morphogenesis ( 0.00211023405139066 ); GO:0021684 cerebellar granular layer formation ( 0.00211023405139066 ); GO:0021707 cerebellar granule cell differentiation ( 0.00211023405139066 ); GO:0010506 regulation of autophagy ( 0.00316376002217755 ); GO:0051001 negative regulation of nitric-oxide synthase activity ( 0.00316376002217755 ); GO:0051386 regulation of nerve growth factor receptor signaling pathway ( 0.00316376002217755 ); GO:0032769 negative regulation of monooxygenase activity ( 0.00421622664055576 ); GO:0004430 1-phosphatidylinositol 4-kinase activity ( 0.00421622664055576 ); GO:0000012 single strand break repair ( 0.00526763491852522 ); GO:0007094 mitotic cell cycle spindle assembly checkpoint ( 0.00631798586717325 ); GO:0031577 spindle checkpoint ( 0.00631798586717325 ); GO:0050771 negative regulation of axonogenesis ( 0.00631798586717325 ); GO:0051354 negative regulation of oxidoreductase activity ( 0.00631798586717325 ); GO:0009223 pyrimidine deoxyribonucleotide catabolic process ( 0.00736728049666979 ); GO:0021697 cerebellar cortex formation ( 0.00736728049666979 ); GO:0031345 negative regulation of cell projection organization ( 0.00736728049666979 ); GO:0031623 receptor internalization ( 0.00736728049666979 ); GO:0004703 G-protein coupled receptor kinase activity ( 0.00736728049666979 ); GO:0006244 pyrimidine nucleotide catabolic process ( 0.00841551981626987 ); GO:0006661 phosphatidylinositol biosynthetic process ( 0.00841551981626987 ); GO:0021533 cell differentiation in hindbrain ( 0.00841551981626987 ); GO:0008253 5'-nucleotidase activity ( 0.00841551981626987 ); GO:0021696 cerebellar cortex morphogenesis ( 0.00946270483431655 ); GO:0042994 cytoplasmic sequestering of transcription factor ( 0.00946270483431655 ); GO:0048011 nerve growth factor receptor signaling pathway ( 0.00946270483431655 ); ----------------KEGG-------------- hsa00760 Nicotinate and nicotinamide metabolism ( 0.0250446468049043 ); hsa04140 Regulation of autophagy ( 0.0332592786128635 ); hsa03410 Base excision repair ( 0.0353026130688546 ); hsa04150 mTOR signaling pathway ( 0.0484843686340907 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.01563801379405 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3017 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00946058996532925 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0045454 cell redox homeostasis ( ); GO:0008140 cAMP response element binding protein binding ( ); GO:0004791 thioredoxin-disulfide reductase activity ( ); GO:0043285 biopolymer catabolic process ( ); GO:0000090 mitotic anaphase ( ); GO:0051322 anaphase ( ); GO:0044265 cellular macromolecule catabolic process ( ); GO:0009057 macromolecule catabolic process ( ); GO:0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor ( ); GO:0019787 small conjugating protein ligase activity ( ); ----------------GO-------------- GO:0045454 cell redox homeostasis ( 0.00181057944644698 ); GO:0008140 cAMP response element binding protein binding ( 0.00316376002217755 ); GO:0004791 thioredoxin-disulfide reductase activity ( 0.00421622664055576 ); GO:0043285 biopolymer catabolic process ( 0.00450762220190862 ); GO:0000090 mitotic anaphase ( 0.00526763491852522 ); GO:0051322 anaphase ( 0.00526763491852522 ); GO:0044265 cellular macromolecule catabolic process ( 0.00613958776191469 ); GO:0009057 macromolecule catabolic process ( 0.00715427066414326 ); GO:0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor ( 0.00841551981626987 ); GO:0019787 small conjugating protein ligase activity ( 0.00882244755872115 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.0219470553226894 ); ----------------RBP-------------- ( 0.0375809061151665 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2949 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$MEF2_03 ( 0.000777961444206372 ); V$RORA2_01 ( 0.0055865942664614 ); TTTNNANAGCYR_UNKNOWN ( 0.00608058365235245 ); ----------------C4-------------- ( ); ----------------C5-------------- CARBOHYDRATE_BIOSYNTHETIC_PROCESS ( 0.000926359293694178 ); GOLGI_APPARATUS ( 0.00134103924744995 ); ACTIN_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.00483687405413727 ); ACTIN_FILAMENT_BASED_PROCESS ( 0.00578185915238834 ); ----------------GOSLIM-------------- GO:0003839 gamma-glutamylcyclotransferase activity ( ); GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity ( ); GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity ( ); GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity ( ); GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity ( ); GO:0018271 biotin-protein ligase activity ( ); GO:0005915 zonula adherens ( ); GO:0003960 NADPH:quinone reductase activity ( ); GO:0017162 aryl hydrocarbon receptor binding ( ); GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity ( ); GO:0005332 gamma-aminobutyric acid:sodium symporter activity ( ); GO:0016051 carbohydrate biosynthetic process ( ); GO:0015185 L-gamma-aminobutyric acid transmembrane transporter activity ( ); GO:0000139 Golgi membrane ( ); GO:0051879 Hsp90 protein binding ( ); GO:0044431 Golgi apparatus part ( ); GO:0005283 sodium:amino acid symporter activity ( ); GO:0009312 oligosaccharide biosynthetic process ( ); GO:0030032 lamellipodium assembly ( ); GO:0017119 Golgi transport complex ( ); ----------------GO-------------- GO:0003839 gamma-glutamylcyclotransferase activity ( 0.00100537877645412 ); GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity ( 0.00100537877645412 ); GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity ( 0.00100537877645412 ); GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity ( 0.00100537877645412 ); GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity ( 0.00100537877645412 ); GO:0018271 biotin-protein ligase activity ( 0.00100537877645412 ); GO:0005915 zonula adherens ( 0.0020097972574753 ); GO:0003960 NADPH:quinone reductase activity ( 0.0020097972574753 ); GO:0017162 aryl hydrocarbon receptor binding ( 0.0020097972574753 ); GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity ( 0.00301325631206484 ); GO:0005332 gamma-aminobutyric acid:sodium symporter activity ( 0.00401575680848321 ); GO:0016051 carbohydrate biosynthetic process ( 0.00465733938191289 ); GO:0015185 L-gamma-aminobutyric acid transmembrane transporter activity ( 0.00501729961424713 ); GO:0000139 Golgi membrane ( 0.00533089891451081 ); GO:0051879 Hsp90 protein binding ( 0.00601788559613115 ); GO:0044431 Golgi apparatus part ( 0.0078407514316077 ); GO:0005283 sodium:amino acid symporter activity ( 0.00801619055165981 ); GO:0009312 oligosaccharide biosynthetic process ( 0.00901391125515327 ); GO:0030032 lamellipodium assembly ( 0.00901391125515327 ); GO:0017119 Golgi transport complex ( 0.00901391125515327 ); ----------------KEGG-------------- hsa00780 Biotin metabolism ( 0.00401575680848321 ); hsa04710 Circadian rhythm ( 0.0129952690544001 ); hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series ( 0.0258300005124468 ); hsa00480 Glutathione metabolism ( 0.0491094395621167 ); ----------------CARTA-------------- ( 0.0307240875884921 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2952 ========================= ----------------C2-------------- ( 0.00397114789624934 ); ----------------C3-------------- AGGGCCA,MIR-328 ( 0.00204163914516453 ); V$EN1_01 ( 0.0031862123718894 ); ----------------C4-------------- GNF2_CCNA1 ( 0.0015346750043264 ); GNF2_MLF1 ( 0.00261747538083675 ); MORF_IL9 ( 0.0031862123718894 ); MORF_RAB3A ( 0.00326102627668084 ); module_538 ( 0.00801619055165981 ); module_450 ( 0.00901391125515327 ); ----------------C5-------------- AMINO_ACID_AND_DERIVATIVE_METABOLIC_PROCESS ( 0.00430782970777685 ); CYTOKINE_ACTIVITY ( 0.00511211656284586 ); AMINE_METABOLIC_PROCESS ( 0.00824792434768926 ); EPITHELIAL_TO_MESENCHYMAL_TRANSITION ( 0.00901391125515327 ); NITROGEN_COMPOUND_METABOLIC_PROCESS ( 0.00981690178848873 ); ----------------GOSLIM-------------- GO:0010692 regulation of alkaline phosphatase activity ( ); GO:0010693 negative regulation of alkaline phosphatase activity ( ); GO:0048818 positive regulation of hair follicle maturation ( ); GO:0048819 regulation of hair follicle maturation ( ); GO:0051794 regulation of catagen ( ); GO:0051795 positive regulation of catagen ( ); GO:0010385 double-stranded methylated DNA binding ( ); GO:0006335 DNA replication-dependent nucleosome assembly ( ); GO:0010631 epithelial cell migration ( ); GO:0010632 regulation of epithelial cell migration ( ); GO:0010634 positive regulation of epithelial cell migration ( ); GO:0010718 positive regulation of epithelial to mesenchymal transition ( ); GO:0010770 positive regulation of cell morphogenesis involved in differentiation ( ); GO:0032872 regulation of stress-activated MAPK cascade ( ); GO:0032874 positive regulation of stress-activated MAPK cascade ( ); GO:0034723 DNA replication-dependent nucleosome organization ( ); GO:0042637 catagen ( ); GO:0045726 positive regulation of integrin biosynthetic process ( ); GO:0005176 ErbB-2 class receptor binding ( ); GO:0006924 activation-induced cell death of T cells ( ); GO:0010717 regulation of epithelial to mesenchymal transition ( ); GO:0033630 positive regulation of cell adhesion mediated by integrin ( ); GO:0045113 regulation of integrin biosynthetic process ( ); GO:0051890 regulation of cardioblast differentiation ( ); GO:0051891 positive regulation of cardioblast differentiation ( ); GO:0060317 cardiac epithelial to mesenchymal transition ( ); GO:0070231 T cell apoptosis ( ); GO:0030197 extracellular matrix constituent, lubricant activity ( ); GO:0007435 salivary gland morphogenesis ( ); GO:0010002 cardioblast differentiation ( ); GO:0032906 transforming growth factor-beta2 production ( ); GO:0032909 regulation of transforming growth factor-beta2 production ( ); GO:0045112 integrin biosynthetic process ( ); GO:0051403 stress-activated MAPK cascade ( ); GO:0051798 positive regulation of hair follicle development ( ); GO:0043495 protein anchor ( ); GO:0008347 glial cell migration ( ); GO:0033628 regulation of cell adhesion mediated by integrin ( ); GO:0042634 regulation of hair cycle ( ); GO:0045684 positive regulation of epidermis development ( ); GO:0051797 regulation of hair follicle development ( ); GO:0006658 phosphatidylserine metabolic process ( ); GO:0007431 salivary gland development ( ); GO:0022612 gland morphogenesis ( ); GO:0030212 hyaluronan metabolic process ( ); GO:0005678 chromatin assembly complex ( ); GO:0005114 type II transforming growth factor beta receptor binding ( ); GO:0030506 ankyrin binding ( ); GO:0014066 regulation of phosphoinositide 3-kinase cascade ( ); GO:0014068 positive regulation of phosphoinositide 3-kinase cascade ( ); GO:0043209 myelin sheath ( ); GO:0043525 positive regulation of neuron apoptosis ( ); GO:0048820 hair follicle maturation ( ); GO:0033627 cell adhesion mediated by integrin ( ); GO:0045682 regulation of epidermis development ( ); GO:0045823 positive regulation of heart contraction ( ); GO:0070227 lymphocyte apoptosis ( ); ----------------GO-------------- GO:0010692 regulation of alkaline phosphatase activity ( 0.00100537877645412 ); GO:0010693 negative regulation of alkaline phosphatase activity ( 0.00100537877645412 ); GO:0048818 positive regulation of hair follicle maturation ( 0.00100537877645412 ); GO:0048819 regulation of hair follicle maturation ( 0.00100537877645412 ); GO:0051794 regulation of catagen ( 0.00100537877645412 ); GO:0051795 positive regulation of catagen ( 0.00100537877645412 ); GO:0010385 double-stranded methylated DNA binding ( 0.00100537877645412 ); GO:0006335 DNA replication-dependent nucleosome assembly ( 0.0020097972574753 ); GO:0010631 epithelial cell migration ( 0.0020097972574753 ); GO:0010632 regulation of epithelial cell migration ( 0.0020097972574753 ); GO:0010634 positive regulation of epithelial cell migration ( 0.0020097972574753 ); GO:0010718 positive regulation of epithelial to mesenchymal transition ( 0.0020097972574753 ); GO:0010770 positive regulation of cell morphogenesis involved in differentiation ( 0.0020097972574753 ); GO:0032872 regulation of stress-activated MAPK cascade ( 0.0020097972574753 ); GO:0032874 positive regulation of stress-activated MAPK cascade ( 0.0020097972574753 ); GO:0034723 DNA replication-dependent nucleosome organization ( 0.0020097972574753 ); GO:0042637 catagen ( 0.0020097972574753 ); GO:0045726 positive regulation of integrin biosynthetic process ( 0.0020097972574753 ); GO:0005176 ErbB-2 class receptor binding ( 0.0020097972574753 ); GO:0006924 activation-induced cell death of T cells ( 0.00301325631206484 ); GO:0010717 regulation of epithelial to mesenchymal transition ( 0.00301325631206484 ); GO:0033630 positive regulation of cell adhesion mediated by integrin ( 0.00301325631206484 ); GO:0045113 regulation of integrin biosynthetic process ( 0.00301325631206484 ); GO:0051890 regulation of cardioblast differentiation ( 0.00301325631206484 ); GO:0051891 positive regulation of cardioblast differentiation ( 0.00301325631206484 ); GO:0060317 cardiac epithelial to mesenchymal transition ( 0.00301325631206484 ); GO:0070231 T cell apoptosis ( 0.00301325631206484 ); GO:0030197 extracellular matrix constituent, lubricant activity ( 0.00301325631206484 ); GO:0007435 salivary gland morphogenesis ( 0.00401575680848321 ); GO:0010002 cardioblast differentiation ( 0.00401575680848321 ); GO:0032906 transforming growth factor-beta2 production ( 0.00401575680848321 ); GO:0032909 regulation of transforming growth factor-beta2 production ( 0.00401575680848321 ); GO:0045112 integrin biosynthetic process ( 0.00401575680848321 ); GO:0051403 stress-activated MAPK cascade ( 0.00401575680848321 ); GO:0051798 positive regulation of hair follicle development ( 0.00401575680848321 ); GO:0043495 protein anchor ( 0.00401575680848321 ); GO:0008347 glial cell migration ( 0.00501729961424713 ); GO:0033628 regulation of cell adhesion mediated by integrin ( 0.00501729961424713 ); GO:0042634 regulation of hair cycle ( 0.00501729961424713 ); GO:0045684 positive regulation of epidermis development ( 0.00501729961424713 ); GO:0051797 regulation of hair follicle development ( 0.00501729961424713 ); GO:0006658 phosphatidylserine metabolic process ( 0.00601788559613115 ); GO:0007431 salivary gland development ( 0.00601788559613115 ); GO:0022612 gland morphogenesis ( 0.00601788559613115 ); GO:0030212 hyaluronan metabolic process ( 0.00601788559613115 ); GO:0005678 chromatin assembly complex ( 0.00601788559613115 ); GO:0005114 type II transforming growth factor beta receptor binding ( 0.00601788559613115 ); GO:0030506 ankyrin binding ( 0.00601788559613115 ); GO:0014066 regulation of phosphoinositide 3-kinase cascade ( 0.00701751562017083 ); GO:0014068 positive regulation of phosphoinositide 3-kinase cascade ( 0.00701751562017083 ); GO:0043209 myelin sheath ( 0.00701751562017083 ); GO:0043525 positive regulation of neuron apoptosis ( 0.00801619055165981 ); GO:0048820 hair follicle maturation ( 0.00801619055165981 ); GO:0033627 cell adhesion mediated by integrin ( 0.00901391125515327 ); GO:0045682 regulation of epidermis development ( 0.00901391125515327 ); GO:0045823 positive regulation of heart contraction ( 0.00901391125515327 ); GO:0070227 lymphocyte apoptosis ( 0.00901391125515327 ); ----------------KEGG-------------- hsa00790 Folate biosynthesis ( 0.0326751746575416 ); hsa00562 Inositol phosphate metabolism ( 0.0471898547750316 ); ----------------CARTA-------------- tffpathway ( 0.0149802450101924 ); lis1pathway ( 0.0169614281781392 ); gcrpathway ( 0.0248483701219921 ); gpcrpathway ( 0.0307240875884921 ); ----------------RBP-------------- ( 0.0265943968075663 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2991 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00895664854168189 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0016287 glycerone-phosphate O-acyltransferase activity ( 0.00549013176611169 ); GO:0030502 negative regulation of bone mineralization ( 0.00549013176611169 ); GO:0051382 kinetochore assembly ( 0.00549013176611169 ); GO:0070168 negative regulation of biomineral formation ( 0.00549013176611169 ); GO:0016413 O-acetyltransferase activity ( 0.00549013176611169 ); GO:0034508 centromere complex assembly ( 0.00549013176611169 ); GO:0051383 kinetochore organization ( 0.00549013176611169 ); GO:0000444 MIS12/MIND type complex ( 0.00549013176611169 ); GO:0032407 MutSalpha complex binding ( 0.00549013176611169 ); GO:0006108 malate metabolic process ( 0.00549013176611169 ); GO:0032404 mismatch repair complex binding ( 0.00549013176611169 ); GO:0016615 malate dehydrogenase activity ( 0.00549013176611169 ); GO:0008509 anion transmembrane transporter activity ( 0.00549013176611169 ); ----------------GO-------------- GO:0016287 glycerone-phosphate O-acyltransferase activity ( 0.00100537877645412 ); GO:0030502 negative regulation of bone mineralization ( 0.00301325631206484 ); GO:0051382 kinetochore assembly ( 0.00301325631206484 ); GO:0070168 negative regulation of biomineral formation ( 0.00301325631206484 ); GO:0016413 O-acetyltransferase activity ( 0.00301325631206484 ); GO:0034508 centromere complex assembly ( 0.00401575680848321 ); GO:0051383 kinetochore organization ( 0.00401575680848321 ); GO:0000444 MIS12/MIND type complex ( 0.00401575680848321 ); GO:0032407 MutSalpha complex binding ( 0.00401575680848321 ); GO:0006108 malate metabolic process ( 0.00601788559613115 ); GO:0032404 mismatch repair complex binding ( 0.00701751562017083 ); GO:0016615 malate dehydrogenase activity ( 0.00801619055165981 ); GO:0008509 anion transmembrane transporter activity ( 0.00801761489858161 ); ----------------KEGG-------------- ( 0.022882289559482 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3000 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005903 brush border ( 0.0020097972574753 ); GO:0016568 chromatin modification ( 0.0020097972574753 ); GO:0042940 D-amino acid transport ( 0.0020097972574753 ); GO:0042941 D-alanine transport ( 0.0020097972574753 ); GO:0042942 D-serine transport ( 0.0020097972574753 ); GO:0045836 positive regulation of meiosis ( 0.0020097972574753 ); GO:0000789 cytoplasmic chromatin ( 0.0020097972574753 ); GO:0000229 cytoplasmic chromosome ( 0.0020097972574753 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.0020097972574753 ); GO:0032329 serine transport ( 0.0020097972574753 ); GO:0015194 L-serine transmembrane transporter activity ( 0.0020097972574753 ); GO:0022889 serine transmembrane transporter activity ( 0.0020097972574753 ); GO:0015889 cobalamin transport ( 0.0020097972574753 ); GO:0015087 cobalt ion transmembrane transporter activity ( 0.0020097972574753 ); GO:0016324 apical plasma membrane ( 0.0020097972574753 ); GO:0006824 cobalt ion transport ( 0.0020097972574753 ); GO:0032328 alanine transport ( 0.0020097972574753 ); GO:0040020 regulation of meiosis ( 0.0020097972574753 ); GO:0051276 chromosome organization ( 0.0020097972574753 ); GO:0045177 apical part of cell ( 0.0020097972574753 ); GO:0051445 regulation of meiotic cell cycle ( 0.0020097972574753 ); GO:0031419 cobalamin binding ( 0.0020097972574753 ); GO:0042995 cell projection ( 0.0020097972574753 ); ----------------GO-------------- GO:0005903 brush border ( 0.000261547395282677 ); GO:0016568 chromatin modification ( 0.000880601459043767 ); GO:0042940 D-amino acid transport ( 0.00100537877645412 ); GO:0042941 D-alanine transport ( 0.00100537877645412 ); GO:0042942 D-serine transport ( 0.00100537877645412 ); GO:0045836 positive regulation of meiosis ( 0.00100537877645412 ); GO:0000789 cytoplasmic chromatin ( 0.00100537877645412 ); GO:0000229 cytoplasmic chromosome ( 0.0020097972574753 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.0025026771028518 ); GO:0032329 serine transport ( 0.00301325631206484 ); GO:0015194 L-serine transmembrane transporter activity ( 0.00301325631206484 ); GO:0022889 serine transmembrane transporter activity ( 0.00301325631206484 ); GO:0015889 cobalamin transport ( 0.00401575680848321 ); GO:0015087 cobalt ion transmembrane transporter activity ( 0.00401575680848321 ); GO:0016324 apical plasma membrane ( 0.00413787918046641 ); GO:0006824 cobalt ion transport ( 0.00501729961424713 ); GO:0032328 alanine transport ( 0.00501729961424713 ); GO:0040020 regulation of meiosis ( 0.00501729961424713 ); GO:0051276 chromosome organization ( 0.00528986010395856 ); GO:0045177 apical part of cell ( 0.00598023386333063 ); GO:0051445 regulation of meiotic cell cycle ( 0.00601788559613115 ); GO:0031419 cobalamin binding ( 0.00701751562017083 ); GO:0042995 cell projection ( 0.00748222914123851 ); ----------------KEGG-------------- hsa04614 Renin-angiotensin system ( 0.0169614281781392 ); hsa00310 Lysine degradation ( 0.0491094395621167 ); ----------------CARTA-------------- ( 0.022882289559482 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group39 ========================= ----------------C2-------------- ( ); ----------------C3-------------- TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 ( 0.00123596386942486 ); V$XBP1_01 ( 0.00445030698752531 ); ----------------C4-------------- ( 0.00666764511175721 ); ----------------C5-------------- MITOCHONDRION ( 0.00366062299241927 ); REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION ( 0.00761672057906437 ); CELL_SOMA ( 0.00951229492480954 ); GROWTH_CONE ( 0.00951229492480954 ); ENDOTHELIAL_CELL_PROLIFERATION ( 0.00951229492480954 ); ----------------GOSLIM-------------- GO:0032268 regulation of cellular protein metabolic process ( 0.0023315959368718 ); GO:0051246 regulation of protein metabolic process ( 0.0023315959368718 ); GO:0032148 activation of protein kinase B activity ( 0.0023315959368718 ); GO:0019895 kinesin-associated mitochondrial adaptor activity ( 0.0023315959368718 ); GO:0031325 positive regulation of cellular metabolic process ( 0.0023315959368718 ); GO:0009893 positive regulation of metabolic process ( 0.0023315959368718 ); GO:0032311 angiogenin-PRI complex ( 0.0023315959368718 ); GO:0004449 isocitrate dehydrogenase (NAD+) activity ( 0.0023315959368718 ); GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity ( 0.0023315959368718 ); GO:0006102 isocitrate metabolic process ( 0.0023315959368718 ); GO:0006651 diacylglycerol biosynthetic process ( 0.0023315959368718 ); GO:0032431 activation of phospholipase A2 activity ( 0.0023315959368718 ); GO:0004448 isocitrate dehydrogenase activity ( 0.0023315959368718 ); GO:0006417 regulation of translation ( 0.0023315959368718 ); GO:0001556 oocyte maturation ( 0.0023315959368718 ); GO:0032429 regulation of phospholipase A2 activity ( 0.0023315959368718 ); GO:0032430 positive regulation of phospholipase A2 activity ( 0.0023315959368718 ); GO:0019894 kinesin binding ( 0.0023315959368718 ); GO:0050811 GABA receptor binding ( 0.0023315959368718 ); GO:0032270 positive regulation of cellular protein metabolic process ( 0.0023315959368718 ); GO:0051247 positive regulation of protein metabolic process ( 0.0023315959368718 ); GO:0042787 protein ubiquitination during ubiquitin-dependent protein catabolic process ( 0.0023315959368718 ); GO:0046339 diacylglycerol metabolic process ( 0.0023315959368718 ); GO:0048662 negative regulation of smooth muscle cell proliferation ( 0.0023315959368718 ); GO:0031398 positive regulation of protein ubiquitination ( 0.0023315959368718 ); GO:0001938 positive regulation of endothelial cell proliferation ( 0.0023315959368718 ); GO:0030279 negative regulation of ossification ( 0.0023315959368718 ); GO:0046460 neutral lipid biosynthetic process ( 0.0023315959368718 ); GO:0046463 acylglycerol biosynthetic process ( 0.0023315959368718 ); GO:0048185 activin binding ( 0.0023315959368718 ); GO:0010608 posttranscriptional regulation of gene expression ( 0.0023315959368718 ); ----------------GO-------------- GO:0032268 regulation of cellular protein metabolic process ( 0.000239435929495198 ); GO:0051246 regulation of protein metabolic process ( 0.000446460542707245 ); GO:0032148 activation of protein kinase B activity ( 0.000955109837631363 ); GO:0019895 kinesin-associated mitochondrial adaptor activity ( 0.000955109837631363 ); GO:0031325 positive regulation of cellular metabolic process ( 0.00162027743623657 ); GO:0009893 positive regulation of metabolic process ( 0.00190664812841279 ); GO:0032311 angiogenin-PRI complex ( 0.00190935540937276 ); GO:0004449 isocitrate dehydrogenase (NAD+) activity ( 0.00190935540937276 ); GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity ( 0.00190935540937276 ); GO:0006102 isocitrate metabolic process ( 0.00286273745387677 ); GO:0006651 diacylglycerol biosynthetic process ( 0.0038152567091998 ); GO:0032431 activation of phospholipase A2 activity ( 0.0038152567091998 ); GO:0004448 isocitrate dehydrogenase activity ( 0.0038152567091998 ); GO:0006417 regulation of translation ( 0.00461704070922556 ); GO:0001556 oocyte maturation ( 0.0047669139128057 ); GO:0032429 regulation of phospholipase A2 activity ( 0.0047669139128057 ); GO:0032430 positive regulation of phospholipase A2 activity ( 0.0047669139128057 ); GO:0019894 kinesin binding ( 0.00571770980156561 ); GO:0050811 GABA receptor binding ( 0.00571770980156561 ); GO:0032270 positive regulation of cellular protein metabolic process ( 0.00605332654380506 ); GO:0051247 positive regulation of protein metabolic process ( 0.00644046989285718 ); GO:0042787 protein ubiquitination during ubiquitin-dependent protein catabolic process ( 0.00666764511175721 ); GO:0046339 diacylglycerol metabolic process ( 0.00761672057906437 ); GO:0048662 negative regulation of smooth muscle cell proliferation ( 0.00761672057906437 ); GO:0031398 positive regulation of protein ubiquitination ( 0.00856493693858129 ); GO:0001938 positive regulation of endothelial cell proliferation ( 0.00951229492480954 ); GO:0030279 negative regulation of ossification ( 0.00951229492480954 ); GO:0046460 neutral lipid biosynthetic process ( 0.00951229492480954 ); GO:0046463 acylglycerol biosynthetic process ( 0.00951229492480954 ); GO:0048185 activin binding ( 0.00951229492480954 ); GO:0010608 posttranscriptional regulation of gene expression ( 0.00969121083072345 ); ----------------KEGG-------------- hsa00062 Fatty acid elongation in mitochondria ( 0.00951229492480954 ); hsa00020 Citrate cycle (TCA cycle) ( 0.0292098229468173 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2484 ========================= ----------------C2-------------- KEGG_PHENYLALANINE_METABOLISM ( 0.000116539826180391 ); KEGG_HISTIDINE_METABOLISM ( 0.000345536010544149 ); KEGG_TYROSINE_METABOLISM ( 0.000693129160615851 ); KEGG_GLYCOLYSIS_GLUCONEOGENESIS ( 0.00157943807966035 ); KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 ( 0.00157943807966035 ); KEGG_DRUG_METABOLISM_CYTOCHROME_P450 ( 0.00168192871966028 ); ----------------C3-------------- ( ); ----------------C4-------------- module_464 ( 7.81122383201296e-05 ); module_194 ( 9.00781732374664e-05 ); GNF2_SERPINB5 ( 0.000255904423804892 ); module_6 ( 0.000482039177591252 ); module_247 ( 0.000504662010064592 ); module_154 ( 0.00212276629705095 ); module_297 ( 0.00242315451529807 ); module_357 ( 0.00242315451529807 ); module_55 ( 0.00626209558112704 ); module_88 ( 0.00634486601095896 ); module_428 ( 0.00761672057906437 ); module_471 ( 0.00856493693858129 ); module_528 ( 0.00951229492480954 ); ----------------C5-------------- OXIDOREDUCTASE_ACTIVITY__ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS__NAD_OR_NADP_AS_ACCEPTOR ( 0.000102887853360856 ); OXIDOREDUCTASE_ACTIVITY__ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS ( 0.00019738336580746 ); AMINO_ACID_METABOLIC_PROCESS ( 0.00230071893727964 ); ALCOHOL_METABOLIC_PROCESS ( 0.00280858494502325 ); AMINO_ACID_AND_DERIVATIVE_METABOLIC_PROCESS ( 0.00388948289559383 ); AMINE_METABOLIC_PROCESS ( 0.00745656323676618 ); NITROGEN_COMPOUND_METABOLIC_PROCESS ( 0.00887881105744916 ); ----------------GOSLIM-------------- GO:0004028 3-chloroallyl aldehyde dehydrogenase activity ( ); GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity ( ); GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ( ); GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors ( ); GO:0002072 optic cup morphogenesis involved in camera-type eye development ( ); GO:0007352 zygotic determination of dorsal/ventral axis ( ); GO:0021768 nucleus accumbens development ( ); GO:0003941 L-serine ammonia-lyase activity ( ); GO:0060166 olfactory pit development ( ); GO:0016403 dimethylargininase activity ( ); GO:0006066 cellular alcohol metabolic process ( ); GO:0016841 ammonia-lyase activity ( ); GO:0047961 glycine N-acyltransferase activity ( ); GO:0009950 dorsal/ventral axis specification ( ); GO:0048857 neural nucleus development ( ); GO:0005498 sterol carrier activity ( ); GO:0005496 steroid binding ( ); GO:0043584 nose development ( ); GO:0000578 embryonic axis specification ( ); GO:0016840 carbon-nitrogen lyase activity ( ); GO:0006527 arginine catabolic process ( ); GO:0006563 L-serine metabolic process ( ); GO:0021756 striatum development ( ); GO:0042573 retinoic acid metabolic process ( ); GO:0021544 subpallium development ( ); GO:0048048 embryonic eye morphogenesis ( ); ----------------GO-------------- GO:0004028 3-chloroallyl aldehyde dehydrogenase activity ( 8.62789477461713e-06 ); GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity ( 1.29344690065441e-05 ); GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ( 0.000162535002070399 ); GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors ( 0.000345536010544149 ); GO:0002072 optic cup morphogenesis involved in camera-type eye development ( 0.000955109837631363 ); GO:0007352 zygotic determination of dorsal/ventral axis ( 0.000955109837631363 ); GO:0021768 nucleus accumbens development ( 0.000955109837631363 ); GO:0003941 L-serine ammonia-lyase activity ( 0.000955109837631363 ); GO:0060166 olfactory pit development ( 0.00190935540937276 ); GO:0016403 dimethylargininase activity ( 0.00190935540937276 ); GO:0006066 cellular alcohol metabolic process ( 0.00280303475896232 ); GO:0016841 ammonia-lyase activity ( 0.00286273745387677 ); GO:0047961 glycine N-acyltransferase activity ( 0.00286273745387677 ); GO:0009950 dorsal/ventral axis specification ( 0.0038152567091998 ); GO:0048857 neural nucleus development ( 0.0047669139128057 ); GO:0005498 sterol carrier activity ( 0.0047669139128057 ); GO:0005496 steroid binding ( 0.00504640426450298 ); GO:0043584 nose development ( 0.00571770980156561 ); GO:0000578 embryonic axis specification ( 0.00666764511175721 ); GO:0016840 carbon-nitrogen lyase activity ( 0.00666764511175721 ); GO:0006527 arginine catabolic process ( 0.00761672057906437 ); GO:0006563 L-serine metabolic process ( 0.00761672057906437 ); GO:0021756 striatum development ( 0.00761672057906437 ); GO:0042573 retinoic acid metabolic process ( 0.00761672057906437 ); GO:0021544 subpallium development ( 0.00856493693858129 ); GO:0048048 embryonic eye morphogenesis ( 0.00856493693858129 ); ----------------KEGG-------------- hsa00360 Phenylalanine metabolism ( 0.000162535002070399 ); hsa00340 Histidine metabolism ( 0.00044834474185735 ); hsa00350 Tyrosine metabolism ( 0.000834923713230978 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.00157943807966035 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.00157943807966035 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.00168192871966028 ); hsa00053 Ascorbate and aldarate metabolism ( 0.00856493693858129 ); hsa00272 Cysteine metabolism ( 0.0123492259799178 ); hsa00641 3-Chloroacrylic acid degradation ( 0.0132931578061943 ); hsa00903 Limonene and pinene degradation ( 0.0170603453216108 ); hsa00410 beta-Alanine metabolism ( 0.0226855874537061 ); hsa00220 Urea cycle and metabolism of amino groups ( 0.0273499783137352 ); hsa00120 Bile acid biosynthesis ( 0.0301384813580553 ); hsa00640 Propanoate metabolism ( 0.0329194096210524 ); hsa00650 Butanoate metabolism ( 0.0356927825389143 ); hsa00260 Glycine, serine and threonine metabolism ( 0.0384586195008807 ); hsa00620 Pyruvate metabolism ( 0.0393788938424828 ); hsa00071 Fatty acid metabolism ( 0.0430516537159338 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0430516537159338 ); hsa00310 Lysine degradation ( 0.0467111078418841 ); hsa00380 Tryptophan metabolism ( 0.0467111078418841 ); hsa00561 Glycerolipid metabolism ( 0.0467111078418841 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2691 ========================= ----------------C2-------------- REACTOME_ELECTRON_TRANSPORT_CHAIN ( 2.82894689014718e-05 ); KEGG_PARKINSONS_DISEASE ( 0.000153505775422953 ); KEGG_OXIDATIVE_PHOSPHORYLATION ( 0.000161837008535475 ); REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION ( 0.000344265328660586 ); REACTOME_DIABETES_PATHWAYS ( 0.000358355805284005 ); KEGG_ALZHEIMERS_DISEASE ( 0.000410199555414819 ); KEGG_HUNTINGTONS_DISEASE ( 0.000537236260847734 ); REACTOME_REGULATION_OF_INSULIN_SECRETION ( 0.000824521377258413 ); REACTOME_INTEGRATION_OF_ENERGY_METABOLISM ( 0.00104741687056592 ); ----------------C3-------------- CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I ( 0.00353803379233615 ); WTGAAAT_UNKNOWN ( 0.00856142532519015 ); ----------------C4-------------- ( ); ----------------C5-------------- SENSORY_PERCEPTION ( 2.79319941411297e-05 ); NEUROLOGICAL_SYSTEM_PROCESS ( 0.0003887918276728 ); SYSTEM_PROCESS ( 0.00168604473803124 ); U12_DEPENDENT_SPLICEOSOME ( 0.00666764511175721 ); PHOTORECEPTOR_CELL_MAINTENANCE ( 0.00951229492480954 ); ----------------GOSLIM-------------- GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( 0.00598550659047899 ); GO:0005747 mitochondrial respiratory chain complex I ( 0.00598550659047899 ); GO:0030964 NADH dehydrogenase complex ( 0.00598550659047899 ); GO:0045271 respiratory chain complex I ( 0.00598550659047899 ); GO:0003954 NADH dehydrogenase activity ( 0.00598550659047899 ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( 0.00598550659047899 ); GO:0050136 NADH dehydrogenase (quinone) activity ( 0.00598550659047899 ); GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor ( 0.00598550659047899 ); GO:0042773 ATP synthesis coupled electron transport ( 0.00598550659047899 ); GO:0042775 mitochondrial ATP synthesis coupled electron transport ( 0.00598550659047899 ); GO:0022904 respiratory electron transport chain ( 0.00598550659047899 ); GO:0005746 mitochondrial respiratory chain ( 0.00598550659047899 ); GO:0016651 oxidoreductase activity, acting on NADH or NADPH ( 0.00598550659047899 ); GO:0006119 oxidative phosphorylation ( 0.00598550659047899 ); GO:0022900 electron transport chain ( 0.00598550659047899 ); GO:0044455 mitochondrial membrane part ( 0.00598550659047899 ); GO:0045839 negative regulation of mitosis ( 0.00598550659047899 ); GO:0007601 visual perception ( 0.00598550659047899 ); GO:0050953 sensory perception of light stimulus ( 0.00598550659047899 ); GO:0005743 mitochondrial inner membrane ( 0.00598550659047899 ); GO:0019866 organelle inner membrane ( 0.00598550659047899 ); GO:0006091 generation of precursor metabolites and energy ( 0.00598550659047899 ); GO:0018344 protein geranylgeranylation ( 0.00598550659047899 ); GO:0004663 Rab-protein geranylgeranyltransferase activity ( 0.00598550659047899 ); GO:0031966 mitochondrial membrane ( 0.00598550659047899 ); GO:0005740 mitochondrial envelope ( 0.00598550659047899 ); GO:0007600 sensory perception ( 0.00598550659047899 ); GO:0016310 phosphorylation ( 0.00598550659047899 ); GO:0018346 protein amino acid prenylation ( 0.00598550659047899 ); GO:0032420 stereocilium ( 0.00598550659047899 ); GO:0004661 protein geranylgeranyltransferase activity ( 0.00598550659047899 ); GO:0018342 protein prenylation ( 0.00598550659047899 ); GO:0032421 stereocilium bundle ( 0.00598550659047899 ); GO:0050890 cognition ( 0.00598550659047899 ); GO:0007605 sensory perception of sound ( 0.00598550659047899 ); GO:0050954 sensory perception of mechanical stimulus ( 0.00598550659047899 ); GO:0050957 equilibrioception ( 0.00598550659047899 ); GO:0008318 protein prenyltransferase activity ( 0.00598550659047899 ); GO:0006793 phosphorus metabolic process ( 0.00598550659047899 ); GO:0006796 phosphate metabolic process ( 0.00598550659047899 ); ----------------GO-------------- GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( 5.16997819016906e-06 ); GO:0005747 mitochondrial respiratory chain complex I ( 5.16997819016906e-06 ); GO:0030964 NADH dehydrogenase complex ( 5.16997819016906e-06 ); GO:0045271 respiratory chain complex I ( 5.16997819016906e-06 ); GO:0003954 NADH dehydrogenase activity ( 5.62275839733729e-06 ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( 5.62275839733729e-06 ); GO:0050136 NADH dehydrogenase (quinone) activity ( 5.62275839733729e-06 ); GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor ( 7.69550684749505e-06 ); GO:0042773 ATP synthesis coupled electron transport ( 9.54361503355266e-06 ); GO:0042775 mitochondrial ATP synthesis coupled electron transport ( 9.54361503355266e-06 ); GO:0022904 respiratory electron transport chain ( 1.32363180764347e-05 ); GO:0005746 mitochondrial respiratory chain ( 2.69586156470608e-05 ); GO:0016651 oxidoreductase activity, acting on NADH or NADPH ( 3.88314963133147e-05 ); GO:0006119 oxidative phosphorylation ( 6.70239571429661e-05 ); GO:0022900 electron transport chain ( 0.000106086146280042 ); GO:0044455 mitochondrial membrane part ( 0.000153505775422953 ); GO:0045839 negative regulation of mitosis ( 0.000955109837631363 ); GO:0007601 visual perception ( 0.00100559816465365 ); GO:0050953 sensory perception of light stimulus ( 0.00100559816465365 ); GO:0005743 mitochondrial inner membrane ( 0.001637376255658 ); GO:0019866 organelle inner membrane ( 0.00208302894315704 ); GO:0006091 generation of precursor metabolites and energy ( 0.0027249818547448 ); GO:0018344 protein geranylgeranylation ( 0.0038152567091998 ); GO:0004663 Rab-protein geranylgeranyltransferase activity ( 0.0038152567091998 ); GO:0031966 mitochondrial membrane ( 0.00401114381244727 ); GO:0005740 mitochondrial envelope ( 0.00462789056718241 ); GO:0007600 sensory perception ( 0.00530051780026831 ); GO:0016310 phosphorylation ( 0.00532509148161463 ); GO:0018346 protein amino acid prenylation ( 0.00571770980156561 ); GO:0032420 stereocilium ( 0.00571770980156561 ); GO:0004661 protein geranylgeranyltransferase activity ( 0.00571770980156561 ); GO:0018342 protein prenylation ( 0.00666764511175721 ); GO:0032421 stereocilium bundle ( 0.00666764511175721 ); GO:0050890 cognition ( 0.00674089650823556 ); GO:0007605 sensory perception of sound ( 0.00693995053176075 ); GO:0050954 sensory perception of mechanical stimulus ( 0.00735187767672859 ); GO:0050957 equilibrioception ( 0.00761672057906437 ); GO:0008318 protein prenyltransferase activity ( 0.00761672057906437 ); GO:0006793 phosphorus metabolic process ( 0.00991125683796663 ); GO:0006796 phosphate metabolic process ( 0.00991125683796663 ); ----------------KEGG-------------- hsa05012 Parkinson's disease ( 0.000161837008535475 ); hsa00190 Oxidative phosphorylation ( 0.00016611071010805 ); hsa05010 Alzheimer's disease ( 0.000441933519409448 ); hsa04140 Regulation of autophagy ( 0.0301384813580553 ); hsa04150 mTOR signaling pathway ( 0.0439677628800091 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO2_PAR-CLIP_(Kishore_2011) ( 0.00835701227385098 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0141522587542421 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.041965127495931 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0147927956675494 ); ============================ group2741 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0016064 immunoglobulin mediated immune response ( ); GO:0019724 B cell mediated immunity ( ); GO:0002449 lymphocyte mediated immunity ( ); GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains ( ); GO:0002250 adaptive immune response ( ); GO:0002443 leukocyte mediated immunity ( ); GO:0004126 cytidine deaminase activity ( ); GO:0005579 membrane attack complex ( ); GO:0002252 immune effector process ( ); ----------------GO-------------- GO:0016064 immunoglobulin mediated immune response ( 0.00133683914858607 ); GO:0019724 B cell mediated immunity ( 0.00143153567345449 ); GO:0002449 lymphocyte mediated immunity ( 0.00294306718131725 ); GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains ( 0.00343719099852151 ); GO:0002250 adaptive immune response ( 0.00351073839171756 ); GO:0002443 leukocyte mediated immunity ( 0.003735788860811 ); GO:0004126 cytidine deaminase activity ( 0.00571770980156561 ); GO:0005579 membrane attack complex ( 0.00666764511175721 ); GO:0002252 immune effector process ( 0.0080988919330372 ); ----------------KEGG-------------- ( 0.0329194096210524 ); ----------------CARTA-------------- ( 0.0319932739750243 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2951 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$NFMUE1_Q6 ( 0.000565333729432339 ); V$SF1_Q6 ( 0.000697959194439737 ); GCTCTTG,MIR-335 ( 0.0020079474783278 ); V$GRE_C ( 0.00366003864266611 ); ACTGTAG,MIR-139 ( 0.00504640426450298 ); TCCCRNNRTGC_UNKNOWN ( 0.00693995053176075 ); V$GR_01 ( 0.00910762938606702 ); ----------------C4-------------- MORF_SNRP70 ( 0.00111384612544999 ); MORF_PPP2CA ( 0.00470148410033463 ); MORF_CDC10 ( 0.00595827921799333 ); ----------------C5-------------- ORGANELLE_ORGANIZATION_AND_BIOGENESIS ( 0.000816664818541037 ); ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE ( 0.00212276629705095 ); CHROMOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.0055850821860658 ); HISTONE_DEACETYLASE_BINDING ( 0.00761672057906437 ); LYSOSOMAL_MEMBRANE ( 0.00951229492480954 ); REGULATION_OF_CELLULAR_PH ( 0.00951229492480954 ); STEROID_HORMONE_RECEPTOR_BINDING ( 0.00951229492480954 ); ----------------GOSLIM-------------- GO:0006325 establishment or maintenance of chromatin architecture ( 0.00198030925686799 ); GO:0051276 chromosome organization ( 0.00424725467088667 ); GO:0016568 chromatin modification ( 0.00198030925686799 ); GO:0006768 biotin metabolic process ( 0.00424725467088667 ); GO:0005854 nascent polypeptide-associated complex ( 0.00198030925686799 ); GO:0016580 Sin3 complex ( 0.00424725467088667 ); GO:0006552 leucine catabolic process ( 0.00198030925686799 ); GO:0021524 visceral motor neuron differentiation ( 0.00424725467088667 ); GO:0004485 methylcrotonoyl-CoA carboxylase activity ( 0.00198030925686799 ); GO:0016922 ligand-dependent nuclear receptor binding ( 0.00424725467088667 ); GO:0006551 leucine metabolic process ( 0.00198030925686799 ); GO:0018242 protein amino acid O-linked glycosylation via serine ( 0.00424725467088667 ); GO:0018243 protein amino acid O-linked glycosylation via threonine ( 0.00198030925686799 ); GO:0048471 perinuclear region of cytoplasm ( 0.00424725467088667 ); GO:0016043 cellular component organization ( 0.00198030925686799 ); GO:0007042 lysosomal lumen acidification ( 0.00424725467088667 ); GO:0006996 organelle organization ( 0.00198030925686799 ); GO:0044249 cellular biosynthetic process ( 0.00424725467088667 ); GO:0005775 vacuolar lumen ( 0.00198030925686799 ); GO:0009374 biotin binding ( 0.00424725467088667 ); GO:0009058 biosynthetic process ( 0.00198030925686799 ); GO:0006350 transcription ( 0.00424725467088667 ); GO:0016421 CoA carboxylase activity ( 0.00198030925686799 ); GO:0034645 cellular macromolecule biosynthetic process ( 0.00424725467088667 ); GO:0009059 macromolecule biosynthetic process ( 0.00198030925686799 ); GO:0016885 ligase activity, forming carbon-carbon bonds ( 0.00424725467088667 ); GO:0010467 gene expression ( 0.00198030925686799 ); GO:0008152 metabolic process ( 0.00424725467088667 ); GO:0009083 branched chain family amino acid catabolic process ( 0.00198030925686799 ); GO:0051452 intracellular pH reduction ( 0.00424725467088667 ); GO:0031290 retinal ganglion cell axon guidance ( 0.00198030925686799 ); GO:0045851 pH reduction ( 0.00424725467088667 ); GO:0018210 peptidyl-threonine modification ( 0.00198030925686799 ); ----------------GO-------------- GO:0006325 establishment or maintenance of chromatin architecture ( 0.000117581914854286 ); GO:0051276 chromosome organization ( 0.000326208042664164 ); GO:0016568 chromatin modification ( 0.000753817234713585 ); GO:0006768 biotin metabolic process ( 0.000955109837631363 ); GO:0005854 nascent polypeptide-associated complex ( 0.000955109837631363 ); GO:0016580 Sin3 complex ( 0.000955109837631363 ); GO:0006552 leucine catabolic process ( 0.00190935540937276 ); GO:0021524 visceral motor neuron differentiation ( 0.00190935540937276 ); GO:0004485 methylcrotonoyl-CoA carboxylase activity ( 0.00190935540937276 ); GO:0016922 ligand-dependent nuclear receptor binding ( 0.00190935540937276 ); GO:0006551 leucine metabolic process ( 0.00286273745387677 ); GO:0018242 protein amino acid O-linked glycosylation via serine ( 0.00286273745387677 ); GO:0018243 protein amino acid O-linked glycosylation via threonine ( 0.00286273745387677 ); GO:0048471 perinuclear region of cytoplasm ( 0.00358502137997105 ); GO:0016043 cellular component organization ( 0.00370689861651879 ); GO:0007042 lysosomal lumen acidification ( 0.0038152567091998 ); GO:0006996 organelle organization ( 0.0042230540945352 ); GO:0044249 cellular biosynthetic process ( 0.00429919533890754 ); GO:0005775 vacuolar lumen ( 0.0047669139128057 ); GO:0009374 biotin binding ( 0.0047669139128057 ); GO:0009058 biosynthetic process ( 0.00495882574942213 ); GO:0006350 transcription ( 0.00545280978202395 ); GO:0016421 CoA carboxylase activity ( 0.00571770980156561 ); GO:0034645 cellular macromolecule biosynthetic process ( 0.00586993876101051 ); GO:0009059 macromolecule biosynthetic process ( 0.00604585782330771 ); GO:0016885 ligase activity, forming carbon-carbon bonds ( 0.00666764511175721 ); GO:0010467 gene expression ( 0.00725867208147849 ); GO:0008152 metabolic process ( 0.00740197100459823 ); GO:0009083 branched chain family amino acid catabolic process ( 0.00761672057906437 ); GO:0051452 intracellular pH reduction ( 0.00761672057906437 ); GO:0031290 retinal ganglion cell axon guidance ( 0.00856493693858129 ); GO:0045851 pH reduction ( 0.00856493693858129 ); GO:0018210 peptidyl-threonine modification ( 0.00951229492480954 ); ----------------KEGG-------------- hsa00512 O-Glycan biosynthesis ( 0.0292098229468173 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0430516537159338 ); hsa00310 Lysine degradation ( 0.0467111078418841 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0451422276186555 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2982 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00724787237162084 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0047560 3-dehydrosphinganine reductase activity ( ); GO:0006420 arginyl-tRNA aminoacylation ( ); GO:0004814 arginine-tRNA ligase activity ( ); GO:0034341 response to interferon-gamma ( ); GO:0034708 methyltransferase complex ( ); GO:0035097 histone methyltransferase complex ( ); ----------------GO-------------- GO:0047560 3-dehydrosphinganine reductase activity ( 0.000955109837631363 ); GO:0006420 arginyl-tRNA aminoacylation ( 0.00286273745387677 ); GO:0004814 arginine-tRNA ligase activity ( 0.00286273745387677 ); GO:0034341 response to interferon-gamma ( 0.00571770980156561 ); GO:0034708 methyltransferase complex ( 0.00761672057906437 ); GO:0035097 histone methyltransferase complex ( 0.00761672057906437 ); ----------------KEGG-------------- hsa00330 Arginine and proline metabolism ( 0.0329194096210524 ); hsa00600 Sphingolipid metabolism ( 0.0366155645651927 ); hsa00970 Aminoacyl-tRNA biosynthesis ( 0.0384586195008807 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0198699048333756 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3005 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$GRE_C ( 0.00366003864266611 ); V$AR_Q2 ( 0.00366003864266611 ); ----------------C4-------------- MORF_PTPRR ( 0.0038122707170364 ); MORF_CDH4 ( 0.00693995053176075 ); MORF_STK17A ( 0.00922302977169107 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0051150 regulation of smooth muscle cell differentiation ( ); GO:0042692 muscle cell differentiation ( ); GO:0051145 smooth muscle cell differentiation ( ); GO:0051147 regulation of muscle cell differentiation ( ); GO:0045445 myoblast differentiation ( ); GO:0048741 skeletal muscle fiber development ( ); GO:0014707 branchiomeric skeletal muscle development ( ); GO:0032074 negative regulation of nuclease activity ( ); GO:0048747 muscle fiber development ( ); GO:0001560 regulation of cell growth by extracellular stimulus ( ); GO:0032069 regulation of nuclease activity ( ); GO:0019870 potassium channel inhibitor activity ( ); GO:0007519 skeletal muscle development ( ); GO:0043267 negative regulation of potassium ion transport ( ); GO:0032002 interleukin-28 receptor complex ( ); GO:0048625 myoblast cell fate commitment ( ); GO:0050691 regulation of defense response to virus by host ( ); GO:0051151 negative regulation of smooth muscle cell differentiation ( ); GO:0043266 regulation of potassium ion transport ( ); GO:0014706 striated muscle development ( ); GO:0045661 regulation of myoblast differentiation ( ); GO:0045987 positive regulation of smooth muscle contraction ( ); GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity ( ); GO:0045933 positive regulation of muscle contraction ( ); GO:0051148 negative regulation of muscle cell differentiation ( ); GO:0043271 negative regulation of ion transport ( ); ----------------GO-------------- GO:0051150 regulation of smooth muscle cell differentiation ( 1.29344690065441e-05 ); GO:0042692 muscle cell differentiation ( 4.05201898357001e-05 ); GO:0051145 smooth muscle cell differentiation ( 5.67174229419617e-05 ); GO:0051147 regulation of muscle cell differentiation ( 0.000146364848654571 ); GO:0045445 myoblast differentiation ( 0.000162535002070399 ); GO:0048741 skeletal muscle fiber development ( 0.000949684287438512 ); GO:0014707 branchiomeric skeletal muscle development ( 0.000955109837631363 ); GO:0032074 negative regulation of nuclease activity ( 0.000955109837631363 ); GO:0048747 muscle fiber development ( 0.0009895331371986 ); GO:0001560 regulation of cell growth by extracellular stimulus ( 0.00190935540937276 ); GO:0032069 regulation of nuclease activity ( 0.00190935540937276 ); GO:0019870 potassium channel inhibitor activity ( 0.00190935540937276 ); GO:0007519 skeletal muscle development ( 0.00280858494502325 ); GO:0043267 negative regulation of potassium ion transport ( 0.00286273745387677 ); GO:0032002 interleukin-28 receptor complex ( 0.00286273745387677 ); GO:0048625 myoblast cell fate commitment ( 0.0038152567091998 ); GO:0050691 regulation of defense response to virus by host ( 0.0038152567091998 ); GO:0051151 negative regulation of smooth muscle cell differentiation ( 0.0038152567091998 ); GO:0043266 regulation of potassium ion transport ( 0.00571770980156561 ); GO:0014706 striated muscle development ( 0.00663819621694931 ); GO:0045661 regulation of myoblast differentiation ( 0.00761672057906437 ); GO:0045987 positive regulation of smooth muscle contraction ( 0.00761672057906437 ); GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity ( 0.00761672057906437 ); GO:0045933 positive regulation of muscle contraction ( 0.00856493693858129 ); GO:0051148 negative regulation of muscle cell differentiation ( 0.00856493693858129 ); GO:0043271 negative regulation of ion transport ( 0.00951229492480954 ); ----------------KEGG-------------- hsa00512 O-Glycan biosynthesis ( 0.0292098229468173 ); hsa03410 Base excision repair ( 0.0319932739750243 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3012 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- CATION_TRANSPORT ( 0.00831838695013337 ); HETEROPHILIC_CELL_ADHESION ( 0.00951229492480954 ); BODY_FLUID_SECRETION ( 0.00951229492480954 ); COFACTOR_TRANSPORTER_ACTIVITY ( 0.00951229492480954 ); ----------------GOSLIM-------------- GO:0008513 secondary active organic cation transmembrane transporter activity ( ); GO:0048730 epidermis morphogenesis ( ); GO:0015697 quaternary ammonium group transport ( ); GO:0045475 locomotor rhythm ( ); GO:0015226 carnitine transporter activity ( ); GO:0007218 neuropeptide signaling pathway ( ); GO:0032190 acrosin binding ( ); GO:0009437 carnitine metabolic process ( ); GO:0015879 carnitine transport ( ); GO:0001515 opioid peptide activity ( ); GO:0048729 tissue morphogenesis ( ); GO:0048512 circadian behavior ( ); GO:0007622 rhythmic behavior ( ); GO:0015695 organic cation transport ( ); GO:0015101 organic cation transmembrane transporter activity ( ); GO:0051183 vitamin transporter activity ( ); GO:0008544 epidermis development ( ); GO:0031069 hair follicle morphogenesis ( ); GO:0045843 negative regulation of striated muscle development ( ); GO:0046330 positive regulation of JNK cascade ( ); ----------------GO-------------- GO:0008513 secondary active organic cation transmembrane transporter activity ( 0.000955109837631363 ); GO:0048730 epidermis morphogenesis ( 0.00152935809695024 ); GO:0015697 quaternary ammonium group transport ( 0.00190935540937276 ); GO:0045475 locomotor rhythm ( 0.00190935540937276 ); GO:0015226 carnitine transporter activity ( 0.00286273745387677 ); GO:0007218 neuropeptide signaling pathway ( 0.00287545228619106 ); GO:0032190 acrosin binding ( 0.0038152567091998 ); GO:0009437 carnitine metabolic process ( 0.0047669139128057 ); GO:0015879 carnitine transport ( 0.0047669139128057 ); GO:0001515 opioid peptide activity ( 0.0047669139128057 ); GO:0048729 tissue morphogenesis ( 0.00478664344704444 ); GO:0048512 circadian behavior ( 0.00571770980156561 ); GO:0007622 rhythmic behavior ( 0.00761672057906437 ); GO:0015695 organic cation transport ( 0.00856493693858129 ); GO:0015101 organic cation transmembrane transporter activity ( 0.00856493693858129 ); GO:0051183 vitamin transporter activity ( 0.00856493693858129 ); GO:0008544 epidermis development ( 0.00887881105744916 ); GO:0031069 hair follicle morphogenesis ( 0.00951229492480954 ); GO:0045843 negative regulation of striated muscle development ( 0.00951229492480954 ); GO:0046330 positive regulation of JNK cascade ( 0.00951229492480954 ); ----------------KEGG-------------- hsa00592 alpha-Linolenic acid metabolism ( 0.0151784580607991 ); hsa00591 Linoleic acid metabolism ( 0.0264187906481081 ); hsa00565 Ether lipid metabolism ( 0.0301384813580553 ); ----------------CARTA-------------- stresspathway ( 2.41168406045897e-05 ); il1rpathway ( 0.0254867584529307 ); tollpathway ( 0.0282803221725771 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group12 ========================= ----------------C2-------------- ( 0.00991082138664157 ); ----------------C3-------------- ACACTGG,MIR-199A,MIR-199B ( 0.000216641860866367 ); ACACTCC,MIR-122A ( 0.00165121540865019 ); STTTCRNTTT_V$IRF_Q6 ( 0.00767852311873194 ); ----------------C4-------------- module_46 ( 0.0045594563224292 ); module_75 ( 0.0047289017012081 ); ----------------C5-------------- ( 0.00901368545837367 ); ----------------GOSLIM-------------- GO:0048856 anatomical structure development ( ); GO:0048241 epinephrine transport ( ); GO:0048242 epinephrine secretion ( ); GO:0005046 KDEL sequence binding ( ); GO:0042415 norepinephrine metabolic process ( ); GO:0070327 thyroid hormone transport ( ); GO:0008190 eukaryotic initiation factor 4E binding ( ); GO:0030492 hemoglobin binding ( ); GO:0046923 ER retention sequence binding ( ); GO:0048731 system development ( ); GO:0008967 phosphoglycolate phosphatase activity ( ); GO:0031369 translation initiation factor binding ( ); GO:0048513 organ development ( ); GO:0006621 protein retention in ER lumen ( ); GO:0030325 adrenal gland development ( ); GO:0016461 unconventional myosin complex ( ); GO:0010257 NADH dehydrogenase complex assembly ( ); GO:0032981 mitochondrial respiratory chain complex I assembly ( ); GO:0033108 mitochondrial respiratory chain complex assembly ( ); GO:0045947 negative regulation of translational initiation ( ); GO:0020027 hemoglobin metabolic process ( ); GO:0010608 posttranscriptional regulation of gene expression ( ); GO:0005833 hemoglobin complex ( ); GO:0050432 catecholamine secretion ( ); ----------------GO-------------- GO:0048856 anatomical structure development ( 0.0017665237847007 ); GO:0048241 epinephrine transport ( 0.00180890850708437 ); GO:0048242 epinephrine secretion ( 0.00180890850708437 ); GO:0005046 KDEL sequence binding ( 0.00180890850708437 ); GO:0042415 norepinephrine metabolic process ( 0.00271220344684953 ); GO:0070327 thyroid hormone transport ( 0.00271220344684953 ); GO:0008190 eukaryotic initiation factor 4E binding ( 0.00361472633965776 ); GO:0030492 hemoglobin binding ( 0.00361472633965776 ); GO:0046923 ER retention sequence binding ( 0.00361472633965776 ); GO:0048731 system development ( 0.00393150184418358 ); GO:0008967 phosphoglycolate phosphatase activity ( 0.00451647780659314 ); GO:0031369 translation initiation factor binding ( 0.00451647780659314 ); GO:0048513 organ development ( 0.00488095141734553 ); GO:0006621 protein retention in ER lumen ( 0.00541745846827302 ); GO:0030325 adrenal gland development ( 0.00541745846827302 ); GO:0016461 unconventional myosin complex ( 0.00541745846827302 ); GO:0010257 NADH dehydrogenase complex assembly ( 0.00631766894484442 ); GO:0032981 mitochondrial respiratory chain complex I assembly ( 0.00631766894484442 ); GO:0033108 mitochondrial respiratory chain complex assembly ( 0.00631766894484442 ); GO:0045947 negative regulation of translational initiation ( 0.00631766894484442 ); GO:0020027 hemoglobin metabolic process ( 0.00721710985598756 ); GO:0010608 posttranscriptional regulation of gene expression ( 0.0087159124263607 ); GO:0005833 hemoglobin complex ( 0.00901368545837367 ); GO:0050432 catecholamine secretion ( 0.00991082138664157 ); ----------------KEGG-------------- hsa00630 Glyoxylate and dicarboxylate metabolism ( 0.013491700357066 ); hsa03050 Proteasome ( 0.0390896414455114 ); hsa04150 mTOR signaling pathway ( 0.0417015981057178 ); hsa05221 Acute myeloid leukemia ( 0.0494972943346854 ); ----------------CARTA-------------- mcmpathway ( 0.00361472633965776 ); flumazenilpathway ( 0.00541745846827302 ); ----------------RBP-------------- ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000125330852164217 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.000661306374450653 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.000846003239685757 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2485 ========================= ----------------C2-------------- REACTOME_OLFACTORY_SIGNALING_PATHWAY ( 0.00333752969558932 ); KEGG_OLFACTORY_TRANSDUCTION ( 0.00469470922117456 ); REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS ( 0.00991082138664157 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00728047398201294 ); ----------------GOSLIM-------------- GO:0007600 sensory perception ( 0.0050770657507953 ); GO:0050890 cognition ( 0.00570793689533557 ); GO:0003058 hormonal regulation of the force of heart contraction ( 0.0050770657507953 ); GO:0004988 mu-opioid receptor activity ( 0.00570793689533557 ); GO:0003008 system process ( 0.0050770657507953 ); GO:0050896 response to stimulus ( 0.00570793689533557 ); GO:0032501 multicellular organismal process ( 0.0050770657507953 ); GO:0050877 neurological system process ( 0.00570793689533557 ); GO:0003099 positive regulation of the force of heart contraction by chemical signal ( 0.0050770657507953 ); GO:0001674 female germ cell nucleus ( 0.00570793689533557 ); GO:0031705 bombesin receptor binding ( 0.0050770657507953 ); GO:0031708 endothelin B receptor binding ( 0.00570793689533557 ); GO:0003057 regulation of the force of heart contraction by chemical signal ( 0.0050770657507953 ); GO:0014820 tonic smooth muscle contraction ( 0.00570793689533557 ); GO:0014824 artery smooth muscle contraction ( 0.0050770657507953 ); GO:0014826 vein smooth muscle contraction ( 0.00570793689533557 ); GO:0004984 olfactory receptor activity ( 0.0050770657507953 ); GO:0007608 sensory perception of smell ( 0.00570793689533557 ); GO:0003100 regulation of systemic arterial blood pressure by endothelin ( 0.0050770657507953 ); GO:0010043 response to zinc ion ( 0.00570793689533557 ); GO:0004930 G-protein coupled receptor activity ( 0.0050770657507953 ); GO:0014829 vascular smooth muscle contraction ( 0.00570793689533557 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.0050770657507953 ); GO:0005886 plasma membrane ( 0.00570793689533557 ); GO:0007606 sensory perception of chemical stimulus ( 0.0050770657507953 ); GO:0002688 regulation of leukocyte chemotaxis ( 0.00570793689533557 ); GO:0002690 positive regulation of leukocyte chemotaxis ( 0.0050770657507953 ); GO:0010460 positive regulation of heart rate ( 0.00570793689533557 ); GO:0048246 macrophage chemotaxis ( 0.0050770657507953 ); GO:0014821 phasic smooth muscle contraction ( 0.00570793689533557 ); GO:0045987 positive regulation of smooth muscle contraction ( 0.0050770657507953 ); GO:0048016 inositol phosphate-mediated signaling ( 0.00570793689533557 ); GO:0004985 opioid receptor activity ( 0.0050770657507953 ); GO:0045823 positive regulation of heart contraction ( 0.00570793689533557 ); GO:0045933 positive regulation of muscle contraction ( 0.0050770657507953 ); GO:0002687 positive regulation of leukocyte migration ( 0.00570793689533557 ); GO:0002685 regulation of leukocyte migration ( 0.0050770657507953 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00570793689533557 ); ----------------GO-------------- GO:0007600 sensory perception ( 0.000468300367431736 ); GO:0050890 cognition ( 0.00063968275794097 ); GO:0003058 hormonal regulation of the force of heart contraction ( 0.000904840898808157 ); GO:0004988 mu-opioid receptor activity ( 0.000904840898808157 ); GO:0003008 system process ( 0.000949016993008613 ); GO:0050896 response to stimulus ( 0.00154471762063123 ); GO:0032501 multicellular organismal process ( 0.00181724231004961 ); GO:0050877 neurological system process ( 0.00230276956847004 ); GO:0003099 positive regulation of the force of heart contraction by chemical signal ( 0.00271220344684953 ); GO:0001674 female germ cell nucleus ( 0.00271220344684953 ); GO:0031705 bombesin receptor binding ( 0.00271220344684953 ); GO:0031708 endothelin B receptor binding ( 0.00271220344684953 ); GO:0003057 regulation of the force of heart contraction by chemical signal ( 0.00361472633965776 ); GO:0014820 tonic smooth muscle contraction ( 0.00361472633965776 ); GO:0014824 artery smooth muscle contraction ( 0.00361472633965776 ); GO:0014826 vein smooth muscle contraction ( 0.00361472633965776 ); GO:0004984 olfactory receptor activity ( 0.00388871012449568 ); GO:0007608 sensory perception of smell ( 0.00439378757379201 ); GO:0003100 regulation of systemic arterial blood pressure by endothelin ( 0.00451647780659314 ); GO:0010043 response to zinc ion ( 0.00451647780659314 ); GO:0004930 G-protein coupled receptor activity ( 0.00460254851409351 ); GO:0014829 vascular smooth muscle contraction ( 0.00541745846827302 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00541745846827302 ); GO:0005886 plasma membrane ( 0.00552821726290864 ); GO:0007606 sensory perception of chemical stimulus ( 0.00574879702526792 ); GO:0002688 regulation of leukocyte chemotaxis ( 0.00631766894484442 ); GO:0002690 positive regulation of leukocyte chemotaxis ( 0.00631766894484442 ); GO:0010460 positive regulation of heart rate ( 0.00631766894484442 ); GO:0048246 macrophage chemotaxis ( 0.00631766894484442 ); GO:0014821 phasic smooth muscle contraction ( 0.00721710985598756 ); GO:0045987 positive regulation of smooth muscle contraction ( 0.00721710985598756 ); GO:0048016 inositol phosphate-mediated signaling ( 0.00721710985598756 ); GO:0004985 opioid receptor activity ( 0.00721710985598756 ); GO:0045823 positive regulation of heart contraction ( 0.00811578182091532 ); GO:0045933 positive regulation of muscle contraction ( 0.00811578182091532 ); GO:0002687 positive regulation of leukocyte migration ( 0.00901368545837367 ); GO:0002685 regulation of leukocyte migration ( 0.00991082138664157 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00991082138664157 ); ----------------KEGG-------------- ( 0.0044596035872581 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2744 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$AP2REP_01 ( 0.00632820846438329 ); CTTTGA_V$LEF1_Q2 ( 0.00713798637949853 ); V$MSX1_01 ( 0.00718248436868634 ); ----------------C4-------------- module_455 ( 0.000452038851910095 ); module_426 ( 0.00240162728801627 ); ----------------C5-------------- HORMONE_ACTIVITY ( 0.000683101001986661 ); GROWTH_FACTOR_ACTIVITY ( 0.0010761623706457 ); NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.00142388144713456 ); NEGATIVE_REGULATION_OF_METABOLIC_PROCESS ( 0.00145654112610737 ); NEGATIVE_REGULATION_OF_CELLULAR_PROCESS ( 0.00205384852532504 ); NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS ( 0.00242450429599916 ); RECEPTOR_BINDING ( 0.00410501478830473 ); TRANSCRIPTION_REPRESSOR_ACTIVITY ( 0.00767852311873194 ); XENOBIOTIC_METABOLIC_PROCESS ( 0.00811578182091532 ); CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00901368545837367 ); RESPONSE_TO_XENOBIOTIC_STIMULUS ( 0.00901368545837367 ); NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION ( 0.00901368545837367 ); REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS ( 0.00991082138664157 ); B_CELL_DIFFERENTIATION ( 0.00991082138664157 ); NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS ( 0.00991082138664157 ); ----------------GOSLIM-------------- GO:0043509 activin A complex ( 0.00663988233940878 ); GO:0048180 activin complex ( 0.00663988233940878 ); GO:0045518 interleukin-22 receptor binding ( 0.00663988233940878 ); GO:0032504 multicellular organism reproduction ( 0.00663988233940878 ); GO:0048609 reproductive process in a multicellular organism ( 0.00663988233940878 ); GO:0001958 endochondral ossification ( 0.00663988233940878 ); GO:0045077 negative regulation of interferon-gamma biosynthetic process ( 0.00663988233940878 ); GO:0060349 bone morphogenesis ( 0.00663988233940878 ); GO:0060350 endochondral bone morphogenesis ( 0.00663988233940878 ); GO:0043511 inhibin complex ( 0.00663988233940878 ); GO:0043512 inhibin A complex ( 0.00663988233940878 ); GO:0048184 follistatin binding ( 0.00663988233940878 ); GO:0032276 regulation of gonadotropin secretion ( 0.00663988233940878 ); GO:0032277 negative regulation of gonadotropin secretion ( 0.00663988233940878 ); GO:0032278 positive regulation of gonadotropin secretion ( 0.00663988233940878 ); GO:0046880 regulation of follicle-stimulating hormone secretion ( 0.00663988233940878 ); GO:0046881 positive regulation of follicle-stimulating hormone secretion ( 0.00663988233940878 ); GO:0046882 negative regulation of follicle-stimulating hormone secretion ( 0.00663988233940878 ); GO:0004802 transketolase activity ( 0.00663988233940878 ); GO:0005179 hormone activity ( 0.00663988233940878 ); GO:0032331 negative regulation of chondrocyte differentiation ( 0.00663988233940878 ); GO:0042541 hemoglobin biosynthetic process ( 0.00663988233940878 ); GO:0043129 surfactant homeostasis ( 0.00663988233940878 ); GO:0045578 negative regulation of B cell differentiation ( 0.00663988233940878 ); GO:0048875 chemical homeostasis within a tissue ( 0.00663988233940878 ); GO:0016744 transferase activity, transferring aldehyde or ketonic groups ( 0.00663988233940878 ); GO:0005102 receptor binding ( 0.00663988233940878 ); GO:0032274 gonadotropin secretion ( 0.00663988233940878 ); GO:0046884 follicle-stimulating hormone secretion ( 0.00663988233940878 ); GO:0042325 regulation of phosphorylation ( 0.00663988233940878 ); GO:0010558 negative regulation of macromolecule biosynthetic process ( 0.00663988233940878 ); GO:0019220 regulation of phosphate metabolic process ( 0.00663988233940878 ); GO:0051174 regulation of phosphorus metabolic process ( 0.00663988233940878 ); GO:0031327 negative regulation of cellular biosynthetic process ( 0.00663988233940878 ); GO:0009890 negative regulation of biosynthetic process ( 0.00663988233940878 ); GO:0045596 negative regulation of cell differentiation ( 0.00663988233940878 ); GO:0032330 regulation of chondrocyte differentiation ( 0.00663988233940878 ); GO:0032925 regulation of activin receptor signaling pathway ( 0.00663988233940878 ); GO:0045648 positive regulation of erythrocyte differentiation ( 0.00663988233940878 ); GO:0002076 osteoblast development ( 0.00663988233940878 ); GO:0020027 hemoglobin metabolic process ( 0.00663988233940878 ); GO:0045620 negative regulation of lymphocyte differentiation ( 0.00663988233940878 ); GO:0048286 alveolus development ( 0.00663988233940878 ); GO:0031324 negative regulation of cellular metabolic process ( 0.00663988233940878 ); GO:0010605 negative regulation of macromolecule metabolic process ( 0.00663988233940878 ); GO:0032924 activin receptor signaling pathway ( 0.00663988233940878 ); GO:0045577 regulation of B cell differentiation ( 0.00663988233940878 ); ----------------GO-------------- GO:0043509 activin A complex ( 0.000904840898808157 ); GO:0048180 activin complex ( 0.000904840898808157 ); GO:0045518 interleukin-22 receptor binding ( 0.000904840898808157 ); GO:0032504 multicellular organism reproduction ( 0.00132683211109542 ); GO:0048609 reproductive process in a multicellular organism ( 0.00132683211109542 ); GO:0001958 endochondral ossification ( 0.00180890850708437 ); GO:0045077 negative regulation of interferon-gamma biosynthetic process ( 0.00180890850708437 ); GO:0060349 bone morphogenesis ( 0.00180890850708437 ); GO:0060350 endochondral bone morphogenesis ( 0.00180890850708437 ); GO:0043511 inhibin complex ( 0.00180890850708437 ); GO:0043512 inhibin A complex ( 0.00180890850708437 ); GO:0048184 follistatin binding ( 0.00180890850708437 ); GO:0032276 regulation of gonadotropin secretion ( 0.00271220344684953 ); GO:0032277 negative regulation of gonadotropin secretion ( 0.00271220344684953 ); GO:0032278 positive regulation of gonadotropin secretion ( 0.00271220344684953 ); GO:0046880 regulation of follicle-stimulating hormone secretion ( 0.00271220344684953 ); GO:0046881 positive regulation of follicle-stimulating hormone secretion ( 0.00271220344684953 ); GO:0046882 negative regulation of follicle-stimulating hormone secretion ( 0.00271220344684953 ); GO:0004802 transketolase activity ( 0.00271220344684953 ); GO:0005179 hormone activity ( 0.0035613094776566 ); GO:0032331 negative regulation of chondrocyte differentiation ( 0.00361472633965776 ); GO:0042541 hemoglobin biosynthetic process ( 0.00361472633965776 ); GO:0043129 surfactant homeostasis ( 0.00361472633965776 ); GO:0045578 negative regulation of B cell differentiation ( 0.00361472633965776 ); GO:0048875 chemical homeostasis within a tissue ( 0.00361472633965776 ); GO:0016744 transferase activity, transferring aldehyde or ketonic groups ( 0.00361472633965776 ); GO:0005102 receptor binding ( 0.00398102633360087 ); GO:0032274 gonadotropin secretion ( 0.00451647780659314 ); GO:0046884 follicle-stimulating hormone secretion ( 0.00451647780659314 ); GO:0042325 regulation of phosphorylation ( 0.00461098527724747 ); GO:0010558 negative regulation of macromolecule biosynthetic process ( 0.00486719492884083 ); GO:0019220 regulation of phosphate metabolic process ( 0.00509956711974213 ); GO:0051174 regulation of phosphorus metabolic process ( 0.00509956711974213 ); GO:0031327 negative regulation of cellular biosynthetic process ( 0.00522366318092291 ); GO:0009890 negative regulation of biosynthetic process ( 0.00537057850672043 ); GO:0045596 negative regulation of cell differentiation ( 0.00596462389424925 ); GO:0032330 regulation of chondrocyte differentiation ( 0.00631766894484442 ); GO:0032925 regulation of activin receptor signaling pathway ( 0.00631766894484442 ); GO:0045648 positive regulation of erythrocyte differentiation ( 0.00631766894484442 ); GO:0002076 osteoblast development ( 0.00721710985598756 ); GO:0020027 hemoglobin metabolic process ( 0.00721710985598756 ); GO:0045620 negative regulation of lymphocyte differentiation ( 0.00721710985598756 ); GO:0048286 alveolus development ( 0.00901368545837367 ); GO:0031324 negative regulation of cellular metabolic process ( 0.00977619980698121 ); GO:0010605 negative regulation of macromolecule metabolic process ( 0.0098827944767122 ); GO:0032924 activin receptor signaling pathway ( 0.00991082138664157 ); GO:0045577 regulation of B cell differentiation ( 0.00991082138664157 ); ----------------KEGG-------------- hsa04060 Cytokine-cytokine receptor interaction ( 0.021876470068423 ); hsa00030 Pentose phosphate pathway ( 0.0232761542128824 ); ----------------CARTA-------------- erk5pathway ( 0.00451647780659314 ); il4pathway ( 0.013491700357066 ); ----------------RBP-------------- ( ); ----------------immu-------------- Cytokines ( 3.41941122591913e-05 ); Cytokine_receptors ( 0.0299449458211532 ); ----------------ARE-------------- ( 0.0461724590993838 ); ============================ group2966 ========================= ----------------C2-------------- KEGG_NOTCH_SIGNALING_PATHWAY ( 0.000816003874916545 ); KEGG_WNT_SIGNALING_PATHWAY ( 0.00798342566334936 ); KEGG_JAK_STAT_SIGNALING_PATHWAY ( 0.0082937529821922 ); REACTOME_A_THIRD_PROTEOLYTIC_CLEAVAGE_RELEASES_NICD ( 0.00901368545837367 ); BIOCARTA_SET_PATHWAY ( 0.00991082138664157 ); REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR ( 0.00991082138664157 ); ----------------C3-------------- ( ); ----------------C4-------------- module_411 ( 0.00206356500791292 ); module_341 ( 0.00228621529100647 ); module_467 ( 0.00631766894484442 ); ----------------C5-------------- N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION ( 0.00451647780659314 ); ENDOPEPTIDASE_ACTIVITY ( 0.00461098527724747 ); EXTRACELLULAR_REGION ( 0.0064694462771319 ); POST_TRANSLATIONAL_PROTEIN_MODIFICATION ( 0.00774057351031132 ); PROTEIN_MATURATION ( 0.00901368545837367 ); AMYLOID_PRECURSOR_PROTEIN_METABOLIC_PROCESS ( 0.00901368545837367 ); INTEGRAL_TO_PLASMA_MEMBRANE ( 0.00941497056192071 ); INTRINSIC_TO_PLASMA_MEMBRANE ( 0.00990062420879432 ); INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHATASE_ACTIVITY ( 0.00991082138664157 ); ----------------GOSLIM-------------- GO:0008173 RNA methyltransferase activity ( ); GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity ( ); GO:0043426 MRF binding ( ); GO:0051577 MyoD binding ( ); GO:0032469 endoplasmic reticulum calcium ion homeostasis ( ); GO:0004438 phosphatidylinositol-3-phosphatase activity ( ); GO:0004809 tRNA (guanine-N2-)-methyltransferase activity ( ); GO:0004905 type I interferon receptor activity ( ); GO:0008174 mRNA methyltransferase activity ( ); GO:0019962 type I interferon binding ( ); GO:0008757 S-adenosylmethionine-dependent methyltransferase activity ( ); GO:0018076 N-terminal peptidyl-lysine acetylation ( ); GO:0018394 peptidyl-lysine acetylation ( ); GO:0004904 interferon receptor activity ( ); GO:0016423 tRNA (guanine) methyltransferase activity ( ); GO:0019961 interferon binding ( ); GO:0005639 integral to nuclear inner membrane ( ); GO:0031229 intrinsic to nuclear inner membrane ( ); GO:0044453 nuclear membrane part ( ); GO:0043425 bHLH transcription factor binding ( ); GO:0006474 N-terminal protein amino acid acetylation ( ); GO:0007220 Notch receptor processing ( ); GO:0042577 lipid phosphatase activity ( ); GO:0001510 RNA methylation ( ); GO:0018409 peptide or protein amino-terminal blocking ( ); GO:0042987 amyloid precursor protein catabolic process ( ); GO:0008175 tRNA methyltransferase activity ( ); GO:0008168 methyltransferase activity ( ); GO:0016741 transferase activity, transferring one-carbon groups ( ); GO:0018205 peptidyl-lysine modification ( ); GO:0031365 N-terminal protein amino acid modification ( ); GO:0000123 histone acetyltransferase complex ( ); ----------------GO-------------- GO:0008173 RNA methyltransferase activity ( 0.00011730260590478 ); GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity ( 0.000904840898808157 ); GO:0043426 MRF binding ( 0.000904840898808157 ); GO:0051577 MyoD binding ( 0.000904840898808157 ); GO:0032469 endoplasmic reticulum calcium ion homeostasis ( 0.00180890850708437 ); GO:0004438 phosphatidylinositol-3-phosphatase activity ( 0.00180890850708437 ); GO:0004809 tRNA (guanine-N2-)-methyltransferase activity ( 0.00180890850708437 ); GO:0004905 type I interferon receptor activity ( 0.00180890850708437 ); GO:0008174 mRNA methyltransferase activity ( 0.00180890850708437 ); GO:0019962 type I interferon binding ( 0.00180890850708437 ); GO:0008757 S-adenosylmethionine-dependent methyltransferase activity ( 0.00200961195005022 ); GO:0018076 N-terminal peptidyl-lysine acetylation ( 0.00271220344684953 ); GO:0018394 peptidyl-lysine acetylation ( 0.00271220344684953 ); GO:0004904 interferon receptor activity ( 0.00361472633965776 ); GO:0016423 tRNA (guanine) methyltransferase activity ( 0.00361472633965776 ); GO:0019961 interferon binding ( 0.00361472633965776 ); GO:0005639 integral to nuclear inner membrane ( 0.00451647780659314 ); GO:0031229 intrinsic to nuclear inner membrane ( 0.00451647780659314 ); GO:0044453 nuclear membrane part ( 0.00451647780659314 ); GO:0043425 bHLH transcription factor binding ( 0.00451647780659314 ); GO:0006474 N-terminal protein amino acid acetylation ( 0.00541745846827302 ); GO:0007220 Notch receptor processing ( 0.00541745846827302 ); GO:0042577 lipid phosphatase activity ( 0.00631766894484442 ); GO:0001510 RNA methylation ( 0.00721710985598756 ); GO:0018409 peptide or protein amino-terminal blocking ( 0.00721710985598756 ); GO:0042987 amyloid precursor protein catabolic process ( 0.00811578182091532 ); GO:0008175 tRNA methyltransferase activity ( 0.00811578182091532 ); GO:0008168 methyltransferase activity ( 0.00850363765903724 ); GO:0016741 transferase activity, transferring one-carbon groups ( 0.0088229434890725 ); GO:0018205 peptidyl-lysine modification ( 0.00901368545837367 ); GO:0031365 N-terminal protein amino acid modification ( 0.00991082138664157 ); GO:0000123 histone acetyltransferase complex ( 0.00991082138664157 ); ----------------KEGG-------------- hsa04330 Notch signaling pathway ( 0.000748112704761355 ); hsa04310 Wnt signaling pathway ( 0.00808626674848511 ); hsa04630 Jak-STAT signaling pathway ( 0.0082937529821922 ); hsa04060 Cytokine-cytokine receptor interaction ( 0.021876470068423 ); hsa05040 Huntington's disease ( 0.0285744250864959 ); ----------------CARTA-------------- il2rbpathway ( 0.000651677913490096 ); ccr3pathway ( 0.00180890850708437 ); smpathway ( 0.00541745846827302 ); mitrpathway ( 0.00631766894484442 ); prionpathway ( 0.00721710985598756 ); pparpathway ( 0.00811578182091532 ); insulinpathway ( 0.00991082138664157 ); ranbp2pathway ( 0.013491700357066 ); ndkdynaminpathway ( 0.0143850069972492 ); g1pathway ( 0.0161693288647338 ); nthipathway ( 0.0161693288647338 ); myosinpathway ( 0.0179505996128563 ); ghpathway ( 0.0276932690520044 ); no1pathway ( 0.034721433037568 ); mtorpathway ( 0.0373446031926254 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0084524776797958 ); ----------------ARE-------------- ( ); ============================ group2442 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_152 ( 0.00462548141406742 ); module_560 ( 0.00936257165269994 ); ----------------C5-------------- REGULATION_OF_NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 0.00141684557691037 ); REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.00345956371831974 ); REGULATION_OF_METABOLIC_PROCESS ( 0.00364197245471925 ); POSITIVE_REGULATION_OF_TRANSCRIPTION__DNA_DEPENDENT ( 0.0042571614122018 ); POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS ( 0.00440276780078606 ); NUCLEUS ( 0.00443989554140269 ); ORGANELLE_LUMEN ( 0.00569272928934032 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00569272928934032 ); POSITIVE_REGULATION_OF_TRANSCRIPTION ( 0.00606890463291804 ); REGULATION_OF_TRANSCRIPTION__DNA_DEPENDENT ( 0.00625095098632236 ); REGULATION_OF_RNA_METABOLIC_PROCESS ( 0.00644410754051974 ); POSITIVE_REGULATION_OF_NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 0.00685839562069042 ); EPITHELIAL_TO_MESENCHYMAL_TRANSITION ( 0.00766644583845111 ); REGULATION_OF_GENE_SPECIFIC_TRANSCRIPTION ( 0.00851485010423025 ); ----------------GOSLIM-------------- GO:0045893 positive regulation of transcription, DNA-dependent ( 0.00284923519431394 ); GO:0051254 positive regulation of RNA metabolic process ( 0.00540072944189906 ); GO:0045941 positive regulation of transcription ( 0.00822472803819343 ); GO:0010638 positive regulation of organelle organization ( 0.00918971794997359 ); GO:0010628 positive regulation of gene expression ( 0.00284923519431394 ); GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00540072944189906 ); GO:0044446 intracellular organelle part ( 0.00822472803819343 ); GO:0044422 organelle part ( 0.00918971794997359 ); GO:0043193 positive regulation of gene-specific transcription ( 0.00284923519431394 ); GO:0010557 positive regulation of macromolecule biosynthetic process ( 0.00540072944189906 ); GO:0031328 positive regulation of cellular biosynthetic process ( 0.00822472803819343 ); GO:0009891 positive regulation of biosynthetic process ( 0.00918971794997359 ); GO:0042773 ATP synthesis coupled electron transport ( 0.00284923519431394 ); GO:0042775 mitochondrial ATP synthesis coupled electron transport ( 0.00540072944189906 ); GO:0022904 respiratory electron transport chain ( 0.00822472803819343 ); GO:0031060 regulation of histone methylation ( 0.00918971794997359 ); GO:0031062 positive regulation of histone methylation ( 0.00284923519431394 ); GO:0008490 arsenite secondary active transmembrane transporter activity ( 0.00540072944189906 ); GO:0015245 fatty acid transporter activity ( 0.00822472803819343 ); GO:0015446 arsenite transmembrane-transporting ATPase activity ( 0.00918971794997359 ); GO:0043225 anion transmembrane-transporting ATPase activity ( 0.00284923519431394 ); GO:0010604 positive regulation of macromolecule metabolic process ( 0.00540072944189906 ); GO:0032583 regulation of gene-specific transcription ( 0.00822472803819343 ); GO:0031325 positive regulation of cellular metabolic process ( 0.00918971794997359 ); GO:0043228 non-membrane-bounded organelle ( 0.00284923519431394 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.00540072944189906 ); GO:0009893 positive regulation of metabolic process ( 0.00822472803819343 ); GO:0005746 mitochondrial respiratory chain ( 0.00918971794997359 ); GO:0044427 chromosomal part ( 0.00284923519431394 ); GO:0002051 osteoblast fate commitment ( 0.00540072944189906 ); GO:0051781 positive regulation of cell division ( 0.00822472803819343 ); GO:0060135 maternal process involved in pregnancy ( 0.00918971794997359 ); GO:0000403 Y-form DNA binding ( 0.00284923519431394 ); GO:0015105 arsenite transmembrane transporter activity ( 0.00540072944189906 ); GO:0045926 negative regulation of growth ( 0.00822472803819343 ); GO:0006119 oxidative phosphorylation ( 0.00918971794997359 ); GO:0006996 organelle organization ( 0.00284923519431394 ); GO:0031058 positive regulation of histone modification ( 0.00540072944189906 ); GO:0046621 negative regulation of organ growth ( 0.00822472803819343 ); GO:0000400 four-way junction DNA binding ( 0.00918971794997359 ); GO:0051130 positive regulation of cellular component organization ( 0.00284923519431394 ); GO:0005694 chromosome ( 0.00540072944189906 ); GO:0022900 electron transport chain ( 0.00822472803819343 ); GO:0031056 regulation of histone modification ( 0.00918971794997359 ); GO:0046329 negative regulation of JNK cascade ( 0.00284923519431394 ); GO:0051974 negative regulation of telomerase activity ( 0.00540072944189906 ); GO:0032154 cleavage furrow ( 0.00822472803819343 ); GO:0003682 chromatin binding ( 0.00918971794997359 ); GO:0043229 intracellular organelle ( 0.00284923519431394 ); GO:0043226 organelle ( 0.00540072944189906 ); GO:0044455 mitochondrial membrane part ( 0.00822472803819343 ); GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c ( 0.00918971794997359 ); GO:0006390 transcription from mitochondrial promoter ( 0.00284923519431394 ); GO:0031116 positive regulation of microtubule polymerization ( 0.00540072944189906 ); GO:0046685 response to arsenic ( 0.00822472803819343 ); GO:0051972 regulation of telomerase activity ( 0.00918971794997359 ); GO:0032270 positive regulation of cellular protein metabolic process ( 0.00284923519431394 ); GO:0070013 intracellular organelle lumen ( 0.00540072944189906 ); GO:0031112 positive regulation of microtubule polymerization or depolymerization ( 0.00822472803819343 ); GO:0031113 regulation of microtubule polymerization ( 0.00918971794997359 ); GO:0032153 cell division site ( 0.00284923519431394 ); GO:0032155 cell division site part ( 0.00540072944189906 ); GO:0008121 ubiquinol-cytochrome-c reductase activity ( 0.00822472803819343 ); GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors ( 0.00918971794997359 ); GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor ( 0.00284923519431394 ); GO:0051247 positive regulation of protein metabolic process ( 0.00540072944189906 ); GO:0000785 chromatin ( 0.00822472803819343 ); GO:0033043 regulation of organelle organization ( 0.00918971794997359 ); GO:0043233 organelle lumen ( 0.00284923519431394 ); GO:0000076 DNA replication checkpoint ( 0.00540072944189906 ); GO:0006030 chitin metabolic process ( 0.00822472803819343 ); GO:0006032 chitin catabolic process ( 0.00918971794997359 ); GO:0006046 N-acetylglucosamine catabolic process ( 0.00284923519431394 ); GO:0016571 histone methylation ( 0.00540072944189906 ); GO:0032297 negative regulation of DNA replication initiation ( 0.00822472803819343 ); GO:0000217 DNA secondary structure binding ( 0.00918971794997359 ); GO:0004568 chitinase activity ( 0.00284923519431394 ); GO:0031974 membrane-enclosed lumen ( 0.00540072944189906 ); GO:0002076 osteoblast development ( 0.00822472803819343 ); GO:0006043 glucosamine catabolic process ( 0.00918971794997359 ); GO:0007090 regulation of S phase of mitotic cell cycle ( 0.00284923519431394 ); GO:0046348 amino sugar catabolic process ( 0.00540072944189906 ); GO:0046785 microtubule polymerization ( 0.00822472803819343 ); GO:0034708 methyltransferase complex ( 0.00918971794997359 ); GO:0035097 histone methyltransferase complex ( 0.00284923519431394 ); GO:0001578 microtubule bundle formation ( 0.00540072944189906 ); GO:0030174 regulation of DNA replication initiation ( 0.00822472803819343 ); GO:0043409 negative regulation of MAPKKK cascade ( 0.00918971794997359 ); GO:0045668 negative regulation of osteoblast differentiation ( 0.00284923519431394 ); GO:0051302 regulation of cell division ( 0.00540072944189906 ); GO:0034961 cellular biopolymer biosynthetic process ( 0.00822472803819343 ); GO:0043284 biopolymer biosynthetic process ( 0.00918971794997359 ); GO:0006351 transcription, DNA-dependent ( 0.00284923519431394 ); GO:0032774 RNA biosynthetic process ( 0.00540072944189906 ); GO:0045736 negative regulation of cyclin-dependent protein kinase activity ( 0.00822472803819343 ); GO:0044429 mitochondrial part ( 0.00918971794997359 ); GO:0016043 cellular component organization ( 0.00284923519431394 ); GO:0015908 fatty acid transport ( 0.00540072944189906 ); GO:0000315 organellar large ribosomal subunit ( 0.00822472803819343 ); GO:0005762 mitochondrial large ribosomal subunit ( 0.00918971794997359 ); GO:0030496 midbody ( 0.00284923519431394 ); ----------------GO-------------- GO:0045893 positive regulation of transcription, DNA-dependent ( 0.000140684914749168 ); GO:0051254 positive regulation of RNA metabolic process ( 0.000144044717230357 ); GO:0045941 positive regulation of transcription ( 0.000271886650409537 ); GO:0010638 positive regulation of organelle organization ( 0.000294826515025917 ); GO:0010628 positive regulation of gene expression ( 0.000296839790527272 ); GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.000354887168298044 ); GO:0044446 intracellular organelle part ( 0.00043878290550143 ); GO:0044422 organelle part ( 0.000455189456164044 ); GO:0043193 positive regulation of gene-specific transcription ( 0.000474555344313159 ); GO:0010557 positive regulation of macromolecule biosynthetic process ( 0.000478513838405835 ); GO:0031328 positive regulation of cellular biosynthetic process ( 0.000550697110932619 ); GO:0009891 positive regulation of biosynthetic process ( 0.000577938060895125 ); GO:0042773 ATP synthesis coupled electron transport ( 0.000636668864751358 ); GO:0042775 mitochondrial ATP synthesis coupled electron transport ( 0.000636668864751358 ); GO:0022904 respiratory electron transport chain ( 0.000789476236244289 ); GO:0031060 regulation of histone methylation ( 0.000854571959985506 ); GO:0031062 positive regulation of histone methylation ( 0.000854571959985506 ); GO:0008490 arsenite secondary active transmembrane transporter activity ( 0.000854571959985506 ); GO:0015245 fatty acid transporter activity ( 0.000854571959985506 ); GO:0015446 arsenite transmembrane-transporting ATPase activity ( 0.000854571959985506 ); GO:0043225 anion transmembrane-transporting ATPase activity ( 0.000854571959985506 ); GO:0010604 positive regulation of macromolecule metabolic process ( 0.000984513403678173 ); GO:0032583 regulation of gene-specific transcription ( 0.000993915579085401 ); GO:0031325 positive regulation of cellular metabolic process ( 0.00103959137226142 ); GO:0043228 non-membrane-bounded organelle ( 0.0010612428457077 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.0010612428457077 ); GO:0009893 positive regulation of metabolic process ( 0.00122578157271162 ); GO:0005746 mitochondrial respiratory chain ( 0.00126121178192291 ); GO:0044427 chromosomal part ( 0.00147592490514283 ); GO:0002051 osteoblast fate commitment ( 0.00170845655060892 ); GO:0051781 positive regulation of cell division ( 0.00170845655060892 ); GO:0060135 maternal process involved in pregnancy ( 0.00170845655060892 ); GO:0000403 Y-form DNA binding ( 0.00170845655060892 ); GO:0015105 arsenite transmembrane transporter activity ( 0.00170845655060892 ); GO:0045926 negative regulation of growth ( 0.00183876060015168 ); GO:0006119 oxidative phosphorylation ( 0.00229947108066108 ); GO:0006996 organelle organization ( 0.00248143249137685 ); GO:0031058 positive regulation of histone modification ( 0.00256165429022182 ); GO:0046621 negative regulation of organ growth ( 0.00256165429022182 ); GO:0000400 four-way junction DNA binding ( 0.00256165429022182 ); GO:0051130 positive regulation of cellular component organization ( 0.0027501508198332 ); GO:0005694 chromosome ( 0.00300805170000174 ); GO:0022900 electron transport chain ( 0.00311327786090834 ); GO:0031056 regulation of histone modification ( 0.00341416569681119 ); GO:0046329 negative regulation of JNK cascade ( 0.00341416569681119 ); GO:0051974 negative regulation of telomerase activity ( 0.00341416569681119 ); GO:0032154 cleavage furrow ( 0.00341416569681119 ); GO:0003682 chromatin binding ( 0.00349770862512649 ); GO:0043229 intracellular organelle ( 0.003653396177002 ); GO:0043226 organelle ( 0.00366744583744601 ); GO:0044455 mitochondrial membrane part ( 0.0039728681191448 ); GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c ( 0.00426599128800031 ); GO:0006390 transcription from mitochondrial promoter ( 0.00426599128800031 ); GO:0031116 positive regulation of microtubule polymerization ( 0.00426599128800031 ); GO:0046685 response to arsenic ( 0.00426599128800031 ); GO:0051972 regulation of telomerase activity ( 0.00426599128800031 ); GO:0032270 positive regulation of cellular protein metabolic process ( 0.00485333791142098 ); GO:0070013 intracellular organelle lumen ( 0.00507937543553541 ); GO:0031112 positive regulation of microtubule polymerization or depolymerization ( 0.00511713158104643 ); GO:0031113 regulation of microtubule polymerization ( 0.00511713158104643 ); GO:0032153 cell division site ( 0.00511713158104643 ); GO:0032155 cell division site part ( 0.00511713158104643 ); GO:0008121 ubiquinol-cytochrome-c reductase activity ( 0.00511713158104643 ); GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors ( 0.00511713158104643 ); GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor ( 0.00511713158104643 ); GO:0051247 positive regulation of protein metabolic process ( 0.00516510406930878 ); GO:0000785 chromatin ( 0.00524446052986726 ); GO:0033043 regulation of organelle organization ( 0.00532438114524433 ); GO:0043233 organelle lumen ( 0.00559676981327536 ); GO:0000076 DNA replication checkpoint ( 0.00596758709284451 ); GO:0006030 chitin metabolic process ( 0.00596758709284451 ); GO:0006032 chitin catabolic process ( 0.00596758709284451 ); GO:0006046 N-acetylglucosamine catabolic process ( 0.00596758709284451 ); GO:0016571 histone methylation ( 0.00596758709284451 ); GO:0032297 negative regulation of DNA replication initiation ( 0.00596758709284451 ); GO:0000217 DNA secondary structure binding ( 0.00596758709284451 ); GO:0004568 chitinase activity ( 0.00596758709284451 ); GO:0031974 membrane-enclosed lumen ( 0.00613330511103183 ); GO:0002076 osteoblast development ( 0.00681735833992358 ); GO:0006043 glucosamine catabolic process ( 0.00681735833992358 ); GO:0007090 regulation of S phase of mitotic cell cycle ( 0.00681735833992358 ); GO:0046348 amino sugar catabolic process ( 0.00681735833992358 ); GO:0046785 microtubule polymerization ( 0.00681735833992358 ); GO:0034708 methyltransferase complex ( 0.00681735833992358 ); GO:0035097 histone methyltransferase complex ( 0.00681735833992358 ); GO:0001578 microtubule bundle formation ( 0.00766644583845111 ); GO:0030174 regulation of DNA replication initiation ( 0.00766644583845111 ); GO:0043409 negative regulation of MAPKKK cascade ( 0.00766644583845111 ); GO:0045668 negative regulation of osteoblast differentiation ( 0.00766644583845111 ); GO:0051302 regulation of cell division ( 0.00766644583845111 ); GO:0034961 cellular biopolymer biosynthetic process ( 0.00799591616551126 ); GO:0043284 biopolymer biosynthetic process ( 0.00799591616551126 ); GO:0006351 transcription, DNA-dependent ( 0.00802491132073898 ); GO:0032774 RNA biosynthetic process ( 0.00809553210585277 ); GO:0045736 negative regulation of cyclin-dependent protein kinase activity ( 0.00851485010423025 ); GO:0044429 mitochondrial part ( 0.0087614819860832 ); GO:0016043 cellular component organization ( 0.00907545645917931 ); GO:0015908 fatty acid transport ( 0.00936257165269994 ); GO:0000315 organellar large ribosomal subunit ( 0.00936257165269994 ); GO:0005762 mitochondrial large ribosomal subunit ( 0.00936257165269994 ); GO:0030496 midbody ( 0.00936257165269994 ); ----------------KEGG-------------- hsa05012 Parkinson's disease ( 0.00411385906662518 ); hsa00190 Oxidative phosphorylation ( 0.00418522177471653 ); hsa05010 Alzheimer's disease ( 0.00797987737079686 ); ----------------CARTA-------------- malpathway ( 0.0194821654096508 ); longevitypathway ( 0.022833686069122 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.000494389985116945 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00063369924622614 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000900398728887999 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000984513403678173 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00107218170598597 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3080 ========================= ----------------C2-------------- ( 0.00769220422452601 ); ----------------C3-------------- ( ); ----------------C4-------------- GCM_RAB10 ( 0.00650200094280725 ); MORF_PSMF1 ( 0.00731619265514056 ); module_65 ( 0.00851485010423025 ); ----------------C5-------------- RNA_BINDING ( 0.00101576112328093 ); PHOSPHORUS_OXYGEN_LYASE_ACTIVITY ( 0.00851485010423025 ); RRNA_PROCESSING ( 0.00936257165269994 ); CYCLASE_ACTIVITY ( 0.00936257165269994 ); ----------------GOSLIM-------------- GO:0009451 RNA modification ( ); GO:0006401 RNA catabolic process ( ); GO:0007624 ultradian rhythm ( ); GO:0043522 leucine zipper domain binding ( ); GO:0004540 ribonuclease activity ( ); GO:0004535 poly(A)-specific ribonuclease activity ( ); GO:0030275 LRR domain binding ( ); GO:0003723 RNA binding ( ); GO:0007252 I-kappaB phosphorylation ( ); GO:0003720 telomerase activity ( ); GO:0003964 RNA-directed DNA polymerase activity ( ); GO:0005697 telomerase holoenzyme complex ( ); GO:0004523 ribonuclease H activity ( ); GO:0000287 magnesium ion binding ( ); GO:0008385 IkappaB kinase complex ( ); GO:0017110 nucleoside-diphosphatase activity ( ); GO:0004518 nuclease activity ( ); GO:0003730 mRNA 3'-UTR binding ( ); GO:0004383 guanylate cyclase activity ( ); GO:0042147 retrograde transport, endosome to Golgi ( ); GO:0003824 catalytic activity ( ); ----------------GO-------------- GO:0009451 RNA modification ( 0.000425704748064777 ); GO:0006401 RNA catabolic process ( 0.000665946762270336 ); GO:0007624 ultradian rhythm ( 0.000854571959985506 ); GO:0043522 leucine zipper domain binding ( 0.000854571959985506 ); GO:0004540 ribonuclease activity ( 0.00114288018537141 ); GO:0004535 poly(A)-specific ribonuclease activity ( 0.00170845655060892 ); GO:0030275 LRR domain binding ( 0.00170845655060892 ); GO:0003723 RNA binding ( 0.00173640917675975 ); GO:0007252 I-kappaB phosphorylation ( 0.00256165429022182 ); GO:0003720 telomerase activity ( 0.00341416569681119 ); GO:0003964 RNA-directed DNA polymerase activity ( 0.00341416569681119 ); GO:0005697 telomerase holoenzyme complex ( 0.00426599128800031 ); GO:0004523 ribonuclease H activity ( 0.00426599128800031 ); GO:0000287 magnesium ion binding ( 0.00467012049338244 ); GO:0008385 IkappaB kinase complex ( 0.00511713158104643 ); GO:0017110 nucleoside-diphosphatase activity ( 0.00511713158104643 ); GO:0004518 nuclease activity ( 0.00615441717765559 ); GO:0003730 mRNA 3'-UTR binding ( 0.00681735833992358 ); GO:0004383 guanylate cyclase activity ( 0.00681735833992358 ); GO:0042147 retrograde transport, endosome to Golgi ( 0.00851485010423025 ); GO:0003824 catalytic activity ( 0.00962150189913753 ); ----------------KEGG-------------- hsa00230 Purine metabolism ( 0.00685839562069042 ); hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis ( 0.0194821654096508 ); hsa03030 DNA replication ( 0.0303352274926096 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0369019098452359 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2190 ========================= ----------------C2-------------- KEGG_PATHWAYS_IN_CANCER ( 0.00206605424942391 ); KEGG_PYRIMIDINE_METABOLISM ( 0.0026464059504915 ); KEGG_NEUROTROPHIN_SIGNALING_PATHWAY ( 0.00450652417568688 ); REACTOME_JNK_PHOSPHORYLATION_AND__ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 ( 0.00721692892746628 ); REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL ( 0.00801578877141951 ); REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES ( 0.00801578877141951 ); REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION ( 0.00801578877141951 ); REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR ( 0.00881404594486668 ); REACTOME_RNA_POLYMERASE_III_CHAIN_ELONGATION ( 0.00961170087218177 ); REACTOME_HUMAN_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX ( 0.00961170087218177 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_DNMT1 ( 0.00321456965718757 ); module_376 ( 0.00561739952916296 ); module_538 ( 0.00641746598835713 ); MORF_HAT1 ( 0.00682214762541374 ); module_450 ( 0.00721692892746628 ); MORF_RPA2 ( 0.00796196687176169 ); module_21 ( 0.00801578877141951 ); MORF_AATF ( 0.00879812487148027 ); module_56 ( 0.00961170087218177 ); module_272 ( 0.00961170087218177 ); ----------------C5-------------- REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE ( 0.00208256087480037 ); I_KAPPAB_KINASE_NF_KAPPAB_CASCADE ( 0.00315539468407901 ); POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY ( 0.00682214762541374 ); PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00721692892746628 ); S_PHASE_OF_MITOTIC_CELL_CYCLE ( 0.00801578877141951 ); PROTEIN_POLYUBIQUITINATION ( 0.00881404594486668 ); INTERLEUKIN_2_PRODUCTION ( 0.00881404594486668 ); PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE ( 0.00961170087218177 ); ----------------GOSLIM-------------- GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00166957276913441 ); GO:0000115 regulation of transcription during S-phase of mitotic cell cycle ( 0.00235876374804965 ); GO:0004588 orotate phosphoribosyltransferase activity ( 0.00477748820632813 ); GO:0004590 orotidine-5'-phosphate decarboxylase activity ( 0.00856903244626776 ); GO:0006350 transcription ( 0.00166957276913441 ); GO:0010467 gene expression ( 0.00235876374804965 ); GO:0006207 'de novo' pyrimidine base biosynthetic process ( 0.00477748820632813 ); GO:0006222 UMP biosynthetic process ( 0.00856903244626776 ); GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process ( 0.00166957276913441 ); GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process ( 0.00235876374804965 ); GO:0019856 pyrimidine base biosynthetic process ( 0.00477748820632813 ); GO:0046049 UMP metabolic process ( 0.00856903244626776 ); GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade ( 0.00166957276913441 ); GO:0009129 pyrimidine nucleoside monophosphate metabolic process ( 0.00235876374804965 ); GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process ( 0.00477748820632813 ); GO:0002726 positive regulation of T cell cytokine production ( 0.00856903244626776 ); GO:0032743 positive regulation of interleukin-2 production ( 0.00166957276913441 ); GO:0034960 cellular biopolymer metabolic process ( 0.00235876374804965 ); GO:0044249 cellular biosynthetic process ( 0.00477748820632813 ); GO:0043283 biopolymer metabolic process ( 0.00856903244626776 ); GO:0003677 DNA binding ( 0.00166957276913441 ); GO:0002369 T cell cytokine production ( 0.00235876374804965 ); GO:0002724 regulation of T cell cytokine production ( 0.00477748820632813 ); GO:0042110 T cell activation ( 0.00856903244626776 ); GO:0044260 cellular macromolecule metabolic process ( 0.00166957276913441 ); GO:0005634 nucleus ( 0.00235876374804965 ); GO:0009058 biosynthetic process ( 0.00477748820632813 ); GO:0034961 cellular biopolymer biosynthetic process ( 0.00856903244626776 ); GO:0043284 biopolymer biosynthetic process ( 0.00166957276913441 ); GO:0007249 I-kappaB kinase/NF-kappaB cascade ( 0.00235876374804965 ); GO:0003676 nucleic acid binding ( 0.00477748820632813 ); GO:0044238 primary metabolic process ( 0.00856903244626776 ); GO:0006206 pyrimidine base metabolic process ( 0.00166957276913441 ); GO:0043170 macromolecule metabolic process ( 0.00235876374804965 ); GO:0002720 positive regulation of cytokine production during immune response ( 0.00477748820632813 ); GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade ( 0.00856903244626776 ); GO:0044237 cellular metabolic process ( 0.00166957276913441 ); GO:0005730 nucleolus ( 0.00235876374804965 ); GO:0002702 positive regulation of production of molecular mediator of immune response ( 0.00477748820632813 ); GO:0010627 regulation of protein kinase cascade ( 0.00856903244626776 ); GO:0034645 cellular macromolecule biosynthetic process ( 0.00166957276913441 ); GO:0009059 macromolecule biosynthetic process ( 0.00235876374804965 ); GO:0046112 nucleobase biosynthetic process ( 0.00477748820632813 ); GO:0005095 GTPase inhibitor activity ( 0.00856903244626776 ); GO:0002711 positive regulation of T cell mediated immunity ( 0.00166957276913441 ); GO:0007250 activation of NF-kappaB-inducing kinase activity ( 0.00235876374804965 ); GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process ( 0.00477748820632813 ); GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process ( 0.00856903244626776 ); ----------------GO-------------- GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.000723955852643211 ); GO:0000115 regulation of transcription during S-phase of mitotic cell cycle ( 0.000804303021162744 ); GO:0004588 orotate phosphoribosyltransferase activity ( 0.000804303021162744 ); GO:0004590 orotidine-5'-phosphate decarboxylase activity ( 0.000804303021162744 ); GO:0006350 transcription ( 0.00172605242824164 ); GO:0010467 gene expression ( 0.00196286738149315 ); GO:0006207 'de novo' pyrimidine base biosynthetic process ( 0.00241108998323147 ); GO:0006222 UMP biosynthetic process ( 0.00241108998323147 ); GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process ( 0.00241108998323147 ); GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process ( 0.00241108998323147 ); GO:0019856 pyrimidine base biosynthetic process ( 0.00241108998323147 ); GO:0046049 UMP metabolic process ( 0.00241108998323147 ); GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade ( 0.00270085443430996 ); GO:0009129 pyrimidine nucleoside monophosphate metabolic process ( 0.00321357477761419 ); GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process ( 0.00321357477761419 ); GO:0002726 positive regulation of T cell cytokine production ( 0.00401545434941519 ); GO:0032743 positive regulation of interleukin-2 production ( 0.00401545434941519 ); GO:0034960 cellular biopolymer metabolic process ( 0.00451921130313377 ); GO:0044249 cellular biosynthetic process ( 0.00468888957360193 ); GO:0043283 biopolymer metabolic process ( 0.00471440229747471 ); GO:0003677 DNA binding ( 0.00474632119179325 ); GO:0002369 T cell cytokine production ( 0.00481672912467734 ); GO:0002724 regulation of T cell cytokine production ( 0.00481672912467734 ); GO:0042110 T cell activation ( 0.0050803249253981 ); GO:0044260 cellular macromolecule metabolic process ( 0.00519007403653276 ); GO:0005634 nucleus ( 0.00531536133854704 ); GO:0009058 biosynthetic process ( 0.00534477471078332 ); GO:0034961 cellular biopolymer biosynthetic process ( 0.00538901604965384 ); GO:0043284 biopolymer biosynthetic process ( 0.00538901604965384 ); GO:0007249 I-kappaB kinase/NF-kappaB cascade ( 0.00545522637068381 ); GO:0003676 nucleic acid binding ( 0.00550359756084057 ); GO:0044238 primary metabolic process ( 0.00554618785732082 ); GO:0006206 pyrimidine base metabolic process ( 0.00561739952916296 ); GO:0043170 macromolecule metabolic process ( 0.00576725283804214 ); GO:0002720 positive regulation of cytokine production during immune response ( 0.00641746598835713 ); GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade ( 0.00641746598835713 ); GO:0044237 cellular metabolic process ( 0.00690047218874987 ); GO:0005730 nucleolus ( 0.00692553934535489 ); GO:0002702 positive regulation of production of molecular mediator of immune response ( 0.00721692892746628 ); GO:0010627 regulation of protein kinase cascade ( 0.0076917590816763 ); GO:0034645 cellular macromolecule biosynthetic process ( 0.00773009652738656 ); GO:0009059 macromolecule biosynthetic process ( 0.00793710797686933 ); GO:0046112 nucleobase biosynthetic process ( 0.00801578877141951 ); GO:0005095 GTPase inhibitor activity ( 0.00801578877141951 ); GO:0002711 positive regulation of T cell mediated immunity ( 0.00881404594486668 ); GO:0007250 activation of NF-kappaB-inducing kinase activity ( 0.00961170087218177 ); GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process ( 0.00961170087218177 ); GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process ( 0.00961170087218177 ); ----------------KEGG-------------- hsa00240 Pyrimidine metabolism ( 0.00238211471827582 ); hsa03020 RNA polymerase ( 0.0199266031147225 ); hsa00983 Drug metabolism - other enzymes ( 0.0348211975620552 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0402549839542866 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0402549839542866 ); ----------------CARTA-------------- lectinpathway ( 0.00641746598835713 ); plcepathway ( 0.00641746598835713 ); eif4pathway ( 0.019136738895201 ); igf1mtorpathway ( 0.0207158710002752 ); ptenpathway ( 0.0207158710002752 ); metpathway ( 0.0348211975620552 ); ----------------RBP-------------- ( 0.00691819735385876 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2743 ========================= ----------------C2-------------- KEGG_PATHWAYS_IN_CANCER ( 0.00206605424942391 ); REACTOME_OPSINS ( 0.00801578877141951 ); ----------------C3-------------- V$E2F_Q2 ( 0.00416432123820044 ); V$ZF5_01 ( 0.00898910232468805 ); ----------------C4-------------- module_33 ( 0.00298526945349916 ); module_113 ( 0.00309674178524664 ); module_211 ( 0.00881404594486668 ); ----------------C5-------------- POLYSACCHARIDE_BINDING ( 0.00037604973007873 ); PATTERN_BINDING ( 0.000588446445308338 ); CARBOHYDRATE_BINDING ( 0.00145916654304065 ); PROTEINACEOUS_EXTRACELLULAR_MATRIX ( 0.00270085443430996 ); EXTRACELLULAR_MATRIX ( 0.00281133541720273 ); N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS ( 0.00961170087218177 ); ----------------GOSLIM-------------- GO:0021965 spinal cord ventral commissure morphogenesis ( 0.00178884343993313 ); GO:0005600 collagen type XIII ( 0.00281977410715544 ); GO:0030936 transmembrane collagen ( 0.00370160808135018 ); GO:0004167 dopachrome isomerase activity ( 0.00178884343993313 ); GO:0033981 D-dopachrome decarboxylase activity ( 0.00281977410715544 ); GO:0005578 proteinaceous extracellular matrix ( 0.00370160808135018 ); GO:0005042 netrin receptor activity ( 0.00178884343993313 ); GO:0008061 chitin binding ( 0.00281977410715544 ); GO:0031012 extracellular matrix ( 0.00370160808135018 ); GO:0022011 myelination in the peripheral nervous system ( 0.00178884343993313 ); GO:0032292 ensheathment of axons in the peripheral nervous system ( 0.00281977410715544 ); GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity ( 0.00370160808135018 ); GO:0030247 polysaccharide binding ( 0.00178884343993313 ); GO:0044421 extracellular region part ( 0.00281977410715544 ); GO:0014044 Schwann cell development ( 0.00370160808135018 ); GO:0006583 melanin biosynthetic process from tyrosine ( 0.00178884343993313 ); GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine ( 0.00281977410715544 ); GO:0019240 citrulline biosynthetic process ( 0.00370160808135018 ); GO:0021952 central nervous system projection neuron axonogenesis ( 0.00178884343993313 ); GO:0021955 central nervous system neuron axonogenesis ( 0.00281977410715544 ); GO:0030319 cellular di-, tri-valent inorganic anion homeostasis ( 0.00370160808135018 ); GO:0030643 cellular phosphate ion homeostasis ( 0.00178884343993313 ); GO:0055061 di-, tri-valent inorganic anion homeostasis ( 0.00281977410715544 ); GO:0055062 phosphate ion homeostasis ( 0.00370160808135018 ); GO:0004668 protein-arginine deiminase activity ( 0.00178884343993313 ); GO:0001871 pattern binding ( 0.00281977410715544 ); GO:0000052 citrulline metabolic process ( 0.00370160808135018 ); GO:0014037 Schwann cell differentiation ( 0.00178884343993313 ); GO:0030002 cellular anion homeostasis ( 0.00281977410715544 ); GO:0042438 melanin biosynthetic process ( 0.00370160808135018 ); GO:0055081 anion homeostasis ( 0.00178884343993313 ); GO:0006030 chitin metabolic process ( 0.00281977410715544 ); GO:0006032 chitin catabolic process ( 0.00370160808135018 ); GO:0006046 N-acetylglucosamine catabolic process ( 0.00178884343993313 ); GO:0006582 melanin metabolic process ( 0.00281977410715544 ); GO:0004568 chitinase activity ( 0.00370160808135018 ); GO:0000272 polysaccharide catabolic process ( 0.00178884343993313 ); GO:0006043 glucosamine catabolic process ( 0.00281977410715544 ); GO:0018195 peptidyl-arginine modification ( 0.00370160808135018 ); GO:0046348 amino sugar catabolic process ( 0.00178884343993313 ); GO:0007275 multicellular organismal development ( 0.00281977410715544 ); GO:0019794 nonprotein amino acid metabolic process ( 0.00370160808135018 ); GO:0006570 tyrosine metabolic process ( 0.00178884343993313 ); GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds ( 0.00281977410715544 ); GO:0009881 photoreceptor activity ( 0.00370160808135018 ); GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines ( 0.00178884343993313 ); ----------------GO-------------- GO:0021965 spinal cord ventral commissure morphogenesis ( 0.000804303021162744 ); GO:0005600 collagen type XIII ( 0.000804303021162744 ); GO:0030936 transmembrane collagen ( 0.000804303021162744 ); GO:0004167 dopachrome isomerase activity ( 0.000804303021162744 ); GO:0033981 D-dopachrome decarboxylase activity ( 0.000804303021162744 ); GO:0005578 proteinaceous extracellular matrix ( 0.00149164939522353 ); GO:0005042 netrin receptor activity ( 0.00160799953994761 ); GO:0008061 chitin binding ( 0.00160799953994761 ); GO:0031012 extracellular matrix ( 0.00170731914807532 ); GO:0022011 myelination in the peripheral nervous system ( 0.00241108998323147 ); GO:0032292 ensheathment of axons in the peripheral nervous system ( 0.00241108998323147 ); GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity ( 0.00241108998323147 ); GO:0030247 polysaccharide binding ( 0.00298100529517975 ); GO:0044421 extracellular region part ( 0.00302316549953127 ); GO:0014044 Schwann cell development ( 0.00321357477761419 ); GO:0006583 melanin biosynthetic process from tyrosine ( 0.00401545434941519 ); GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine ( 0.00401545434941519 ); GO:0019240 citrulline biosynthetic process ( 0.00401545434941519 ); GO:0021952 central nervous system projection neuron axonogenesis ( 0.00401545434941519 ); GO:0021955 central nervous system neuron axonogenesis ( 0.00401545434941519 ); GO:0030319 cellular di-, tri-valent inorganic anion homeostasis ( 0.00401545434941519 ); GO:0030643 cellular phosphate ion homeostasis ( 0.00401545434941519 ); GO:0055061 di-, tri-valent inorganic anion homeostasis ( 0.00401545434941519 ); GO:0055062 phosphate ion homeostasis ( 0.00401545434941519 ); GO:0004668 protein-arginine deiminase activity ( 0.00401545434941519 ); GO:0001871 pattern binding ( 0.00403100366065498 ); GO:0000052 citrulline metabolic process ( 0.00481672912467734 ); GO:0014037 Schwann cell differentiation ( 0.00481672912467734 ); GO:0030002 cellular anion homeostasis ( 0.00481672912467734 ); GO:0042438 melanin biosynthetic process ( 0.00481672912467734 ); GO:0055081 anion homeostasis ( 0.00481672912467734 ); GO:0006030 chitin metabolic process ( 0.00561739952916296 ); GO:0006032 chitin catabolic process ( 0.00561739952916296 ); GO:0006046 N-acetylglucosamine catabolic process ( 0.00561739952916296 ); GO:0006582 melanin metabolic process ( 0.00561739952916296 ); GO:0004568 chitinase activity ( 0.00561739952916296 ); GO:0000272 polysaccharide catabolic process ( 0.00641746598835713 ); GO:0006043 glucosamine catabolic process ( 0.00641746598835713 ); GO:0018195 peptidyl-arginine modification ( 0.00641746598835713 ); GO:0046348 amino sugar catabolic process ( 0.00641746598835713 ); GO:0007275 multicellular organismal development ( 0.00724170505575761 ); GO:0019794 nonprotein amino acid metabolic process ( 0.00801578877141951 ); GO:0006570 tyrosine metabolic process ( 0.00881404594486668 ); GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds ( 0.00881404594486668 ); GO:0009881 photoreceptor activity ( 0.00961170087218177 ); GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines ( 0.00961170087218177 ); ----------------KEGG-------------- hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series ( 0.0207158710002752 ); hsa00530 Aminosugars metabolism ( 0.0238669876032404 ); hsa05217 Basal cell carcinoma ( 0.0433471147066282 ); hsa04340 Hedgehog signaling pathway ( 0.0448896753561558 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0495033779291125 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0246532801168762 ); ============================ group3054 ========================= ----------------C2-------------- REACTOME_TRANSLATION ( 0.00403100366065498 ); BIOCARTA_RANMS_PATHWAY ( 0.00801578877141951 ); BIOCARTA_EPONFKB_PATHWAY ( 0.00881404594486668 ); ----------------C3-------------- V$OCT1_Q6 ( 0.000516463915341117 ); TTTNNANAGCYR_UNKNOWN ( 0.00389973152728013 ); MGGAAGTG_V$GABP_B ( 0.00727480197288792 ); V$E2F_Q6_01 ( 0.00778135283468406 ); V$E2F1_Q4_01 ( 0.00778135283468406 ); V$YY1_02 ( 0.00787142233927688 ); V$CART1_01 ( 0.00796196687176169 ); V$E2F_Q3_01 ( 0.00814447812929141 ); V$E2F_Q4_01 ( 0.00814447812929141 ); V$OCT1_02 ( 0.00832888083234604 ); V$E2F1_Q6_01 ( 0.00870333753367106 ); V$GATA1_04 ( 0.00977161111115976 ); V$FREAC3_01 ( 0.00977161111115976 ); V$SRF_Q4 ( 0.00987150534793309 ); V$MYCMAX_01 ( 0.00997185958307883 ); ----------------C4-------------- module_54 ( 0.00087509827854122 ); module_274 ( 0.00189360069413856 ); module_441 ( 0.00321357477761419 ); module_9 ( 0.00358053997660592 ); ----------------C5-------------- CELLULAR_BIOSYNTHETIC_PROCESS ( 0.00180543679271411 ); GTPASE_REGULATOR_ACTIVITY ( 0.00389973152728013 ); CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.00416432123820044 ); BIOSYNTHETIC_PROCESS ( 0.00539793961150609 ); XENOBIOTIC_METABOLIC_PROCESS ( 0.00721692892746628 ); RESPONSE_TO_TOXIN ( 0.00801578877141951 ); RESPONSE_TO_XENOBIOTIC_STIMULUS ( 0.00801578877141951 ); RESPONSE_TO_HEAT ( 0.00801578877141951 ); CHROMOSOME_CONDENSATION ( 0.00801578877141951 ); TRANSLATION ( 0.00860901874335771 ); GLIOGENESIS ( 0.00881404594486668 ); TRANSMISSION_OF_NERVE_IMPULSE ( 0.00957320546728538 ); RESPONSE_TO_CARBOHYDRATE_STIMULUS ( 0.00961170087218177 ); ORGAN_DEVELOPMENT ( 0.0097319897519899 ); ----------------GOSLIM-------------- GO:0015785 UDP-galactose transport ( 0.000360513768626079 ); GO:0021757 caudate nucleus development ( 0.0045896547224614 ); GO:0021758 putamen development ( 0.000360513768626079 ); GO:0046602 regulation of mitotic centrosome separation ( 0.0045896547224614 ); GO:0046604 positive regulation of mitotic centrosome separation ( 0.000360513768626079 ); GO:0046607 positive regulation of centrosome cycle ( 0.0045896547224614 ); GO:0003955 NAD(P)H dehydrogenase (quinone) activity ( 0.000360513768626079 ); GO:0004348 glucosylceramidase activity ( 0.0045896547224614 ); GO:0005459 UDP-galactose transmembrane transporter activity ( 0.000360513768626079 ); GO:0044444 cytoplasmic part ( 0.0045896547224614 ); GO:0042391 regulation of membrane potential ( 0.000360513768626079 ); GO:0007080 mitotic metaphase plate congression ( 0.0045896547224614 ); GO:0007100 mitotic centrosome separation ( 0.000360513768626079 ); GO:0046605 regulation of centrosome cycle ( 0.0045896547224614 ); GO:0015781 pyrimidine nucleotide-sugar transport ( 0.000360513768626079 ); GO:0051310 metaphase plate congression ( 0.0045896547224614 ); GO:0016595 glutamate binding ( 0.000360513768626079 ); GO:0015780 nucleotide-sugar transport ( 0.0045896547224614 ); GO:0048857 neural nucleus development ( 0.000360513768626079 ); GO:0051299 centrosome separation ( 0.0045896547224614 ); GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex ( 0.000360513768626079 ); GO:0015165 pyrimidine nucleotide sugar transmembrane transporter activity ( 0.0045896547224614 ); GO:0050000 chromosome localization ( 0.000360513768626079 ); GO:0051303 establishment of chromosome localization ( 0.0045896547224614 ); GO:0005851 eukaryotic translation initiation factor 2B complex ( 0.000360513768626079 ); GO:0008278 cohesin complex ( 0.0045896547224614 ); GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity ( 0.000360513768626079 ); GO:0005092 GDP-dissociation inhibitor activity ( 0.0045896547224614 ); GO:0016594 glycine binding ( 0.000360513768626079 ); GO:0006012 galactose metabolic process ( 0.0045896547224614 ); GO:0004128 cytochrome-b5 reductase activity ( 0.000360513768626079 ); GO:0005338 nucleotide-sugar transmembrane transporter activity ( 0.0045896547224614 ); GO:0021756 striatum development ( 0.000360513768626079 ); GO:0008536 Ran GTPase binding ( 0.0045896547224614 ); GO:0016653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ( 0.000360513768626079 ); GO:0017040 ceramidase activity ( 0.0045896547224614 ); GO:0043229 intracellular organelle ( 0.000360513768626079 ); GO:0043226 organelle ( 0.0045896547224614 ); GO:0021544 subpallium development ( 0.000360513768626079 ); GO:0042274 ribosomal small subunit biogenesis ( 0.0045896547224614 ); GO:0008328 ionotropic glutamate receptor complex ( 0.000360513768626079 ); GO:0014003 oligodendrocyte development ( 0.0045896547224614 ); GO:0044424 intracellular part ( 0.000360513768626079 ); GO:0043231 intracellular membrane-bounded organelle ( 0.0045896547224614 ); GO:0043227 membrane-bounded organelle ( 0.000360513768626079 ); ----------------GO-------------- GO:0015785 UDP-galactose transport ( 0.000804303021162744 ); GO:0021757 caudate nucleus development ( 0.000804303021162744 ); GO:0021758 putamen development ( 0.000804303021162744 ); GO:0046602 regulation of mitotic centrosome separation ( 0.000804303021162744 ); GO:0046604 positive regulation of mitotic centrosome separation ( 0.000804303021162744 ); GO:0046607 positive regulation of centrosome cycle ( 0.000804303021162744 ); GO:0003955 NAD(P)H dehydrogenase (quinone) activity ( 0.000804303021162744 ); GO:0004348 glucosylceramidase activity ( 0.00160799953994761 ); GO:0005459 UDP-galactose transmembrane transporter activity ( 0.00160799953994761 ); GO:0044444 cytoplasmic part ( 0.00182223915306659 ); GO:0042391 regulation of membrane potential ( 0.00208256087480037 ); GO:0007080 mitotic metaphase plate congression ( 0.00241108998323147 ); GO:0007100 mitotic centrosome separation ( 0.00241108998323147 ); GO:0046605 regulation of centrosome cycle ( 0.00241108998323147 ); GO:0015781 pyrimidine nucleotide-sugar transport ( 0.00321357477761419 ); GO:0051310 metaphase plate congression ( 0.00321357477761419 ); GO:0016595 glutamate binding ( 0.00321357477761419 ); GO:0015780 nucleotide-sugar transport ( 0.00401545434941519 ); GO:0048857 neural nucleus development ( 0.00401545434941519 ); GO:0051299 centrosome separation ( 0.00401545434941519 ); GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex ( 0.00401545434941519 ); GO:0015165 pyrimidine nucleotide sugar transmembrane transporter activity ( 0.00401545434941519 ); GO:0050000 chromosome localization ( 0.00481672912467734 ); GO:0051303 establishment of chromosome localization ( 0.00481672912467734 ); GO:0005851 eukaryotic translation initiation factor 2B complex ( 0.00481672912467734 ); GO:0008278 cohesin complex ( 0.00481672912467734 ); GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity ( 0.00481672912467734 ); GO:0005092 GDP-dissociation inhibitor activity ( 0.00481672912467734 ); GO:0016594 glycine binding ( 0.00481672912467734 ); GO:0006012 galactose metabolic process ( 0.00561739952916296 ); GO:0004128 cytochrome-b5 reductase activity ( 0.00561739952916296 ); GO:0005338 nucleotide-sugar transmembrane transporter activity ( 0.00561739952916296 ); GO:0021756 striatum development ( 0.00641746598835713 ); GO:0008536 Ran GTPase binding ( 0.00641746598835713 ); GO:0016653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ( 0.00641746598835713 ); GO:0017040 ceramidase activity ( 0.00641746598835713 ); GO:0043229 intracellular organelle ( 0.00685920750379316 ); GO:0043226 organelle ( 0.00688315118052202 ); GO:0021544 subpallium development ( 0.00721692892746628 ); GO:0042274 ribosomal small subunit biogenesis ( 0.00721692892746628 ); GO:0008328 ionotropic glutamate receptor complex ( 0.00721692892746628 ); GO:0014003 oligodendrocyte development ( 0.00881404594486668 ); GO:0044424 intracellular part ( 0.0092384908058058 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00976319944004535 ); GO:0043227 membrane-bounded organelle ( 0.00979719353097262 ); ----------------KEGG-------------- hsa00460 Cyanoamino acid metabolism ( 0.00721692892746628 ); hsa00592 alpha-Linolenic acid metabolism ( 0.0127963065978743 ); hsa04010 MAPK signaling pathway ( 0.018758611901891 ); hsa00100 Biosynthesis of steroids ( 0.019136738895201 ); hsa00591 Linoleic acid metabolism ( 0.0222926194501127 ); hsa01032 Glycan structures - degradation ( 0.0246532801168762 ); hsa00565 Ether lipid metabolism ( 0.0254389788137914 ); hsa00600 Sphingolipid metabolism ( 0.0309222779503094 ); hsa00500 Starch and sucrose metabolism ( 0.0340425920947263 ); hsa00590 Arachidonic acid metabolism ( 0.0425749588187856 ); hsa05014 Amyotrophic lateral sclerosis (ALS) ( 0.0433471147066282 ); ----------------CARTA-------------- p35alzheimerspathway ( 0.00881404594486668 ); mhcpathway ( 0.0104087539774609 ); mitochondriapathway ( 0.0127963065978743 ); hsp27pathway ( 0.0143850069972495 ); ----------------RBP-------------- AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000769361669108104 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00435558026000205 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00573599704571953 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0265764398879261 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3117 ========================= ----------------C2-------------- ( 0.00961170087218177 ); ----------------C3-------------- GGGCGGR_V$SP1_Q6 ( 0.00447442658503924 ); TGCCTTA,MIR-124A ( 0.00590464169927805 ); V$ZID_01 ( 0.00796196687176169 ); ----------------C4-------------- MORF_THPO ( 0.00423174517022629 ); MORF_PRKCA ( 0.00805298570917681 ); MORF_MAP2K7 ( 0.00842178967447303 ); MORF_CTSB ( 0.00889338004037942 ); MORF_IL4 ( 0.00918194538043532 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0033037 polysaccharide localization ( ); GO:0042335 cuticle development ( ); GO:0002063 chondrocyte development ( ); GO:0035121 tail morphogenesis ( ); GO:0047756 chondroitin 4-sulfotransferase activity ( ); GO:0048703 embryonic viscerocranium morphogenesis ( ); GO:0050665 hydrogen peroxide biosynthetic process ( ); GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity ( ); GO:0016174 NAD(P)H oxidase activity ( ); GO:0034481 chondroitin sulfotransferase activity ( ); GO:0030204 chondroitin sulfate metabolic process ( ); GO:0030206 chondroitin sulfate biosynthetic process ( ); GO:0016021 integral to membrane ( ); GO:0031224 intrinsic to membrane ( ); GO:0050650 chondroitin sulfate proteoglycan biosynthetic process ( ); GO:0050664 oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor ( ); GO:0048701 embryonic cranial skeleton morphogenesis ( ); GO:0050654 chondroitin sulfate proteoglycan metabolic process ( ); GO:0051591 response to cAMP ( ); GO:0042554 superoxide release ( ); ----------------GO-------------- GO:0033037 polysaccharide localization ( 0.000804303021162744 ); GO:0042335 cuticle development ( 0.000804303021162744 ); GO:0002063 chondrocyte development ( 0.00160799953994761 ); GO:0035121 tail morphogenesis ( 0.00241108998323147 ); GO:0047756 chondroitin 4-sulfotransferase activity ( 0.00241108998323147 ); GO:0048703 embryonic viscerocranium morphogenesis ( 0.00321357477761419 ); GO:0050665 hydrogen peroxide biosynthetic process ( 0.00321357477761419 ); GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity ( 0.00401545434941519 ); GO:0016174 NAD(P)H oxidase activity ( 0.00401545434941519 ); GO:0034481 chondroitin sulfotransferase activity ( 0.00401545434941519 ); GO:0030204 chondroitin sulfate metabolic process ( 0.00561739952916296 ); GO:0030206 chondroitin sulfate biosynthetic process ( 0.00561739952916296 ); GO:0016021 integral to membrane ( 0.0060675234766425 ); GO:0031224 intrinsic to membrane ( 0.00701343382062334 ); GO:0050650 chondroitin sulfate proteoglycan biosynthetic process ( 0.00721692892746628 ); GO:0050664 oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor ( 0.00721692892746628 ); GO:0048701 embryonic cranial skeleton morphogenesis ( 0.00801578877141951 ); GO:0050654 chondroitin sulfate proteoglycan metabolic process ( 0.00801578877141951 ); GO:0051591 response to cAMP ( 0.00881404594486668 ); GO:0042554 superoxide release ( 0.00961170087218177 ); ----------------KEGG-------------- hsa00920 Sulfur metabolism ( 0.0104087539774609 ); hsa00603 Glycosphingolipid biosynthesis - globo series ( 0.0112052056845209 ); hsa00532 Chondroitin sulfate biosynthesis ( 0.0159713102632257 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0495033779291125 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0473512448164191 ); ----------------ARE-------------- ( ); ============================ group3181 ========================= ----------------C2-------------- ( 0.00881404594486668 ); ----------------C3-------------- V$GR_01 ( 0.00648780747002508 ); V$HNF1_C ( 0.00823644341060483 ); V$MYOD_Q6_01 ( 0.00889338004037942 ); WCAANNNYCAG_UNKNOWN ( 0.00898910232468805 ); V$LMO2COM_01 ( 0.00987150534793309 ); ----------------C4-------------- ( ); ----------------C5-------------- COFACTOR_TRANSPORT ( 0.00881404594486668 ); VITAMIN_BINDING ( 0.00961170087218177 ); ----------------GOSLIM-------------- GO:0051216 cartilage development ( ); GO:0048705 skeletal system morphogenesis ( ); GO:0003986 acetyl-CoA hydrolase activity ( ); GO:0042415 norepinephrine metabolic process ( ); GO:0006651 diacylglycerol biosynthetic process ( ); GO:0032331 negative regulation of chondrocyte differentiation ( ); GO:0035117 embryonic arm morphogenesis ( ); GO:0035140 arm morphogenesis ( ); GO:0043129 surfactant homeostasis ( ); GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ( ); GO:0045880 positive regulation of smoothened signaling pathway ( ); GO:0048875 chemical homeostasis within a tissue ( ); GO:0050847 progesterone receptor signaling pathway ( ); GO:0003846 2-acylglycerol O-acyltransferase activity ( ); GO:0004144 diacylglycerol O-acyltransferase activity ( ); GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress ( ); GO:0043620 regulation of transcription in response to stress ( ); GO:0035035 histone acetyltransferase binding ( ); GO:0015884 folic acid transport ( ); GO:0032330 regulation of chondrocyte differentiation ( ); GO:0008589 regulation of smoothened signaling pathway ( ); GO:0046339 diacylglycerol metabolic process ( ); GO:0046847 filopodium formation ( ); GO:0009887 organ morphogenesis ( ); GO:0030035 microspike assembly ( ); GO:0035115 embryonic forelimb morphogenesis ( ); GO:0046460 neutral lipid biosynthetic process ( ); GO:0046463 acylglycerol biosynthetic process ( ); GO:0045017 glycerolipid biosynthetic process ( ); GO:0046504 glycerol ether biosynthetic process ( ); GO:0060070 Wnt receptor signaling pathway through beta-catenin ( ); GO:0043009 chordate embryonic development ( ); GO:0035136 forelimb morphogenesis ( ); GO:0005542 folic acid binding ( ); GO:0009792 embryonic development ending in birth or egg hatching ( ); ----------------GO-------------- GO:0051216 cartilage development ( 0.000755718654780942 ); GO:0048705 skeletal system morphogenesis ( 0.00115108950885259 ); GO:0003986 acetyl-CoA hydrolase activity ( 0.00160799953994761 ); GO:0042415 norepinephrine metabolic process ( 0.00241108998323147 ); GO:0006651 diacylglycerol biosynthetic process ( 0.00321357477761419 ); GO:0032331 negative regulation of chondrocyte differentiation ( 0.00321357477761419 ); GO:0035117 embryonic arm morphogenesis ( 0.00321357477761419 ); GO:0035140 arm morphogenesis ( 0.00321357477761419 ); GO:0043129 surfactant homeostasis ( 0.00321357477761419 ); GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ( 0.00321357477761419 ); GO:0045880 positive regulation of smoothened signaling pathway ( 0.00321357477761419 ); GO:0048875 chemical homeostasis within a tissue ( 0.00321357477761419 ); GO:0050847 progesterone receptor signaling pathway ( 0.00321357477761419 ); GO:0003846 2-acylglycerol O-acyltransferase activity ( 0.00321357477761419 ); GO:0004144 diacylglycerol O-acyltransferase activity ( 0.00321357477761419 ); GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress ( 0.00401545434941519 ); GO:0043620 regulation of transcription in response to stress ( 0.00401545434941519 ); GO:0035035 histone acetyltransferase binding ( 0.00401545434941519 ); GO:0015884 folic acid transport ( 0.00481672912467734 ); GO:0032330 regulation of chondrocyte differentiation ( 0.00561739952916296 ); GO:0008589 regulation of smoothened signaling pathway ( 0.00641746598835713 ); GO:0046339 diacylglycerol metabolic process ( 0.00641746598835713 ); GO:0046847 filopodium formation ( 0.00721692892746628 ); GO:0009887 organ morphogenesis ( 0.00751342705173051 ); GO:0030035 microspike assembly ( 0.00801578877141951 ); GO:0035115 embryonic forelimb morphogenesis ( 0.00801578877141951 ); GO:0046460 neutral lipid biosynthetic process ( 0.00801578877141951 ); GO:0046463 acylglycerol biosynthetic process ( 0.00801578877141951 ); GO:0045017 glycerolipid biosynthetic process ( 0.00881404594486668 ); GO:0046504 glycerol ether biosynthetic process ( 0.00881404594486668 ); GO:0060070 Wnt receptor signaling pathway through beta-catenin ( 0.00881404594486668 ); GO:0043009 chordate embryonic development ( 0.00937664832776413 ); GO:0035136 forelimb morphogenesis ( 0.00961170087218177 ); GO:0005542 folic acid binding ( 0.00961170087218177 ); GO:0009792 embryonic development ending in birth or egg hatching ( 0.00967217758121774 ); ----------------KEGG-------------- hsa00620 Pyruvate metabolism ( 0.0332633978155989 ); hsa05217 Basal cell carcinoma ( 0.0433471147066282 ); hsa04340 Hedgehog signaling pathway ( 0.0448896753561558 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3215 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_243 ( 0.00150015381893835 ); GCM_ACTG1 ( 0.00377051092333085 ); module_540 ( 0.00801578877141951 ); MORF_ACP1 ( 0.00908529100945049 ); ----------------C5-------------- ( 0.00881404594486668 ); ----------------GOSLIM-------------- GO:0006710 androgen catabolic process ( ); GO:0006880 intracellular sequestering of iron ion ( ); GO:0008043 intracellular ferritin complex ( ); GO:0070288 ferritin complex ( ); GO:0004322 ferroxidase activity ( ); GO:0016724 oxidoreductase activity, oxidizing metal ions, oxygen as acceptor ( ); GO:0016722 oxidoreductase activity, oxidizing metal ions ( ); GO:0042447 hormone catabolic process ( ); GO:0008199 ferric iron binding ( ); GO:0008209 androgen metabolic process ( ); GO:0004303 estradiol 17-beta-dehydrogenase activity ( ); ----------------GO-------------- GO:0006710 androgen catabolic process ( 0.00160799953994761 ); GO:0006880 intracellular sequestering of iron ion ( 0.00160799953994761 ); GO:0008043 intracellular ferritin complex ( 0.00160799953994761 ); GO:0070288 ferritin complex ( 0.00160799953994761 ); GO:0004322 ferroxidase activity ( 0.00241108998323147 ); GO:0016724 oxidoreductase activity, oxidizing metal ions, oxygen as acceptor ( 0.00241108998323147 ); GO:0016722 oxidoreductase activity, oxidizing metal ions ( 0.00561739952916296 ); GO:0042447 hormone catabolic process ( 0.00641746598835713 ); GO:0008199 ferric iron binding ( 0.00641746598835713 ); GO:0008209 androgen metabolic process ( 0.00721692892746628 ); GO:0004303 estradiol 17-beta-dehydrogenase activity ( 0.00801578877141951 ); ----------------KEGG-------------- hsa00860 Porphyrin and chlorophyll metabolism ( 0.0262240841125669 ); hsa03050 Proteasome ( 0.0348211975620552 ); ----------------CARTA-------------- nkcellspathway ( 0.0175552197719616 ); no1pathway ( 0.0309222779503094 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0104155322661365 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0265764398879261 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0305802626105246 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0372653353247618 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group1236 ========================= ----------------C2-------------- REACTOME_TELOMERE_MAINTENANCE ( 0.00142657813093427 ); REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND ( 0.00751650136894899 ); REACTOME_TRANSFORMATION_OF_LANOSTEROL_TO_CHOLESTEROL ( 0.00751650136894899 ); REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE ( 0.00826524413812157 ); ----------------C3-------------- ( 0.00757667396081684 ); ----------------C4-------------- ( ); ----------------C5-------------- CHROMOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00348293398824351 ); ENDONUCLEASE_ACTIVITY_GO_0016893 ( 0.00826524413812157 ); ENDORIBONUCLEASE_ACTIVITY ( 0.00976114832942221 ); ----------------GOSLIM-------------- GO:0044446 intracellular organelle part ( 0.000195405981681663 ); GO:0044422 organelle part ( 0.00224029534214385 ); GO:0034470 ncRNA processing ( 0.00354093096422227 ); GO:0034660 ncRNA metabolic process ( 0.00425178663461325 ); GO:0006396 RNA processing ( 0.00493038776455509 ); GO:0044424 intracellular part ( 0.00541958512844189 ); GO:0043229 intracellular organelle ( 0.00639175024213058 ); GO:0043226 organelle ( 0.00871774116086932 ); GO:0044428 nuclear part ( 0.000195405981681663 ); GO:0005622 intracellular ( 0.00224029534214385 ); GO:0033617 mitochondrial respiratory chain complex IV assembly ( 0.00354093096422227 ); GO:0060380 regulation of single-stranded telomeric DNA binding ( 0.00425178663461325 ); GO:0060381 positive regulation of single-stranded telomeric DNA binding ( 0.00493038776455509 ); GO:0005750 mitochondrial respiratory chain complex III ( 0.00541958512844189 ); GO:0045275 respiratory chain complex III ( 0.00639175024213058 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00871774116086932 ); GO:0043227 membrane-bounded organelle ( 0.000195405981681663 ); GO:0004540 ribonuclease activity ( 0.00224029534214385 ); GO:0044427 chromosomal part ( 0.00354093096422227 ); GO:0008033 tRNA processing ( 0.00425178663461325 ); GO:0051973 positive regulation of telomerase activity ( 0.00493038776455509 ); GO:0003680 AT DNA binding ( 0.00541958512844189 ); GO:0050613 delta14-sterol reductase activity ( 0.00639175024213058 ); GO:0070182 DNA polymerase binding ( 0.00871774116086932 ); GO:0005694 chromosome ( 0.000195405981681663 ); GO:0031848 protection from non-homologous end joining at telomere ( 0.00224029534214385 ); GO:0043247 telomere maintenance in response to DNA damage ( 0.00354093096422227 ); GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00425178663461325 ); GO:0000228 nuclear chromosome ( 0.00493038776455509 ); GO:0006399 tRNA metabolic process ( 0.00541958512844189 ); GO:0070013 intracellular organelle lumen ( 0.00639175024213058 ); GO:0043228 non-membrane-bounded organelle ( 0.00871774116086932 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.000195405981681663 ); GO:0016233 telomere capping ( 0.00224029534214385 ); GO:0032202 telomere assembly ( 0.00354093096422227 ); GO:0032211 negative regulation of telomere maintenance via telomerase ( 0.00425178663461325 ); GO:0008429 phosphatidylethanolamine binding ( 0.00493038776455509 ); GO:0043233 organelle lumen ( 0.00541958512844189 ); GO:0031974 membrane-enclosed lumen ( 0.00639175024213058 ); GO:0051972 regulation of telomerase activity ( 0.00871774116086932 ); GO:0070198 protein localization to telomere ( 0.000195405981681663 ); GO:0032210 regulation of telomere maintenance via telomerase ( 0.00224029534214385 ); GO:0034502 protein localization to chromosome ( 0.00354093096422227 ); GO:0005655 nucleolar ribonuclease P complex ( 0.00425178663461325 ); GO:0030677 ribonuclease P complex ( 0.00493038776455509 ); GO:0030681 multimeric ribonuclease P complex ( 0.00541958512844189 ); GO:0004518 nuclease activity ( 0.00639175024213058 ); GO:0010257 NADH dehydrogenase complex assembly ( 0.00871774116086932 ); GO:0032981 mitochondrial respiratory chain complex I assembly ( 0.000195405981681663 ); GO:0033108 mitochondrial respiratory chain complex assembly ( 0.00224029534214385 ); GO:0008535 respiratory chain complex IV assembly ( 0.00354093096422227 ); GO:0032205 negative regulation of telomere maintenance ( 0.00425178663461325 ); GO:0000782 telomere cap complex ( 0.00493038776455509 ); GO:0000783 nuclear telomere cap complex ( 0.00541958512844189 ); GO:0000175 3'-5'-exoribonuclease activity ( 0.00639175024213058 ); GO:0004526 ribonuclease P activity ( 0.00871774116086932 ); GO:0005689 U12-dependent spliceosome ( 0.000195405981681663 ); GO:0044452 nucleolar part ( 0.00224029534214385 ); GO:0031981 nuclear lumen ( 0.00354093096422227 ); GO:0032204 regulation of telomere maintenance ( 0.00425178663461325 ); GO:0000178 exosome (RNase complex) ( 0.00493038776455509 ); GO:0004549 tRNA-specific ribonuclease activity ( 0.00541958512844189 ); GO:0004532 exoribonuclease activity ( 0.00639175024213058 ); GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters ( 0.00871774116086932 ); GO:0006996 organelle organization ( 0.000195405981681663 ); ----------------GO-------------- GO:0044446 intracellular organelle part ( 1.08188272473676e-05 ); GO:0044422 organelle part ( 1.13028941158717e-05 ); GO:0034470 ncRNA processing ( 0.000193343621395337 ); GO:0034660 ncRNA metabolic process ( 0.000381117834794936 ); GO:0006396 RNA processing ( 0.000406156824717174 ); GO:0044424 intracellular part ( 0.000408840757548174 ); GO:0043229 intracellular organelle ( 0.000420939468251065 ); GO:0043226 organelle ( 0.000422745334067892 ); GO:0044428 nuclear part ( 0.000437411514787843 ); GO:0005622 intracellular ( 0.00070843048256427 ); GO:0033617 mitochondrial respiratory chain complex IV assembly ( 0.000754034082340427 ); GO:0060380 regulation of single-stranded telomeric DNA binding ( 0.000754034082340427 ); GO:0060381 positive regulation of single-stranded telomeric DNA binding ( 0.000754034082340427 ); GO:0005750 mitochondrial respiratory chain complex III ( 0.000754034082340427 ); GO:0045275 respiratory chain complex III ( 0.000754034082340427 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00083480071986351 ); GO:0043227 membrane-bounded organelle ( 0.000838379439982481 ); GO:0004540 ribonuclease activity ( 0.000885742534555137 ); GO:0044427 chromosomal part ( 0.00100766676919158 ); GO:0008033 tRNA processing ( 0.00100926084694163 ); GO:0051973 positive regulation of telomerase activity ( 0.00150753747509946 ); GO:0003680 AT DNA binding ( 0.00150753747509946 ); GO:0050613 delta14-sterol reductase activity ( 0.00150753747509946 ); GO:0070182 DNA polymerase binding ( 0.00150753747509946 ); GO:0005694 chromosome ( 0.00206556648894525 ); GO:0031848 protection from non-homologous end joining at telomere ( 0.00226051052511589 ); GO:0043247 telomere maintenance in response to DNA damage ( 0.00226051052511589 ); GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00228082287970962 ); GO:0000228 nuclear chromosome ( 0.00251717294527712 ); GO:0006399 tRNA metabolic process ( 0.00271889643712913 ); GO:0070013 intracellular organelle lumen ( 0.00277224128805513 ); GO:0043228 non-membrane-bounded organelle ( 0.00291694847202488 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.00291694847202488 ); GO:0016233 telomere capping ( 0.00301295357901865 ); GO:0032202 telomere assembly ( 0.00301295357901865 ); GO:0032211 negative regulation of telomere maintenance via telomerase ( 0.00301295357901865 ); GO:0008429 phosphatidylethanolamine binding ( 0.00301295357901865 ); GO:0043233 organelle lumen ( 0.00306296771647239 ); GO:0031974 membrane-enclosed lumen ( 0.00336547977877537 ); GO:0051972 regulation of telomerase activity ( 0.00376486698322753 ); GO:0070198 protein localization to telomere ( 0.00376486698322753 ); GO:0032210 regulation of telomere maintenance via telomerase ( 0.00451625108395437 ); GO:0034502 protein localization to chromosome ( 0.00451625108395437 ); GO:0005655 nucleolar ribonuclease P complex ( 0.00451625108395437 ); GO:0030677 ribonuclease P complex ( 0.00451625108395437 ); GO:0030681 multimeric ribonuclease P complex ( 0.00451625108395437 ); GO:0004518 nuclease activity ( 0.0047951857328524 ); GO:0010257 NADH dehydrogenase complex assembly ( 0.00526710622720084 ); GO:0032981 mitochondrial respiratory chain complex I assembly ( 0.00526710622720084 ); GO:0033108 mitochondrial respiratory chain complex assembly ( 0.00526710622720084 ); GO:0008535 respiratory chain complex IV assembly ( 0.0060174327587601 ); GO:0032205 negative regulation of telomere maintenance ( 0.0060174327587601 ); GO:0000782 telomere cap complex ( 0.00676723102421728 ); GO:0000783 nuclear telomere cap complex ( 0.00676723102421728 ); GO:0000175 3'-5'-exoribonuclease activity ( 0.00751650136894899 ); GO:0004526 ribonuclease P activity ( 0.00751650136894899 ); GO:0005689 U12-dependent spliceosome ( 0.00826524413812157 ); GO:0044452 nucleolar part ( 0.00826524413812157 ); GO:0031981 nuclear lumen ( 0.00840580980333076 ); GO:0032204 regulation of telomere maintenance ( 0.00901345967669576 ); GO:0000178 exosome (RNase complex) ( 0.00901345967669576 ); GO:0004549 tRNA-specific ribonuclease activity ( 0.00901345967669576 ); GO:0004532 exoribonuclease activity ( 0.00976114832942221 ); GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters ( 0.00976114832942221 ); GO:0006996 organelle organization ( 0.00995507160008122 ); ----------------KEGG-------------- hsa03430 Mismatch repair ( 0.0172091318316675 ); hsa00100 Biosynthesis of steroids ( 0.0179510474342097 ); hsa03440 Homologous recombination ( 0.0209134856135691 ); hsa03410 Base excision repair ( 0.0253415077537568 ); hsa03030 DNA replication ( 0.0268133566722748 ); hsa03420 Nucleotide excision repair ( 0.0319485074695727 ); ----------------CARTA-------------- ( 0.0334110416211668 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.00277871716167146 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00338267351472557 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00446729076610416 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00720401715112665 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0212541257166892 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2660 ========================= ----------------C2-------------- ( 0.00174334116572763 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00676723102421728 ); ----------------GOSLIM-------------- GO:0015747 urate transport ( ); GO:0015143 urate transmembrane transporter activity ( ); GO:0005589 collagen type VI ( ); GO:0004909 interleukin-1, Type I, activating receptor activity ( ); GO:0019967 interleukin-1, Type I, activating binding ( ); GO:0019236 response to pheromone ( ); GO:0016503 pheromone receptor activity ( ); GO:0004908 interleukin-1 receptor activity ( ); GO:0030934 anchoring collagen ( ); GO:0019966 interleukin-1 binding ( ); GO:0031092 platelet alpha granule membrane ( ); GO:0031526 brush border membrane ( ); GO:0007043 cell-cell junction assembly ( ); ----------------GO-------------- GO:0015747 urate transport ( 0.000754034082340427 ); GO:0015143 urate transmembrane transporter activity ( 0.000754034082340427 ); GO:0005589 collagen type VI ( 0.00150753747509946 ); GO:0004909 interleukin-1, Type I, activating receptor activity ( 0.00150753747509946 ); GO:0019967 interleukin-1, Type I, activating binding ( 0.00150753747509946 ); GO:0019236 response to pheromone ( 0.00376486698322753 ); GO:0016503 pheromone receptor activity ( 0.00376486698322753 ); GO:0004908 interleukin-1 receptor activity ( 0.00526710622720084 ); GO:0030934 anchoring collagen ( 0.00676723102421728 ); GO:0019966 interleukin-1 binding ( 0.00676723102421728 ); GO:0031092 platelet alpha granule membrane ( 0.00751650136894899 ); GO:0031526 brush border membrane ( 0.00751650136894899 ); GO:0007043 cell-cell junction assembly ( 0.00976114832942221 ); ----------------KEGG-------------- ( 0.00174334116572763 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2983 ========================= ----------------C2-------------- REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY ( 0.00751650136894899 ); REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY ( 0.00901345967669576 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- MICROTUBULE_BINDING ( 0.000259803875827709 ); TUBULIN_BINDING ( 0.00053883550943189 ); CYTOSKELETAL_PROTEIN_BINDING ( 0.00615009009664355 ); ----------------GOSLIM-------------- GO:0008017 microtubule binding ( ); GO:0032239 regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport ( ); GO:0032241 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport ( ); GO:0046831 regulation of RNA export from nucleus ( ); GO:0046833 positive regulation of RNA export from nucleus ( ); GO:0015631 tubulin binding ( ); GO:0006408 snRNA export from nucleus ( ); GO:0051030 snRNA transport ( ); GO:0005845 mRNA cap binding complex ( ); GO:0034518 RNA cap binding complex ( ); GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity ( ); GO:0006290 pyrimidine dimer repair ( ); GO:0008092 cytoskeletal protein binding ( ); GO:0046686 response to cadmium ion ( ); GO:0046688 response to copper ion ( ); GO:0000339 RNA cap binding ( ); GO:0008171 O-methyltransferase activity ( ); GO:0006878 cellular copper ion homeostasis ( ); GO:0042147 retrograde transport, endosome to Golgi ( ); GO:0055070 copper ion homeostasis ( ); GO:0031201 SNARE complex ( ); GO:0006916 anti-apoptosis ( ); ----------------GO-------------- GO:0008017 microtubule binding ( 0.00053883550943189 ); GO:0032239 regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport ( 0.000754034082340427 ); GO:0032241 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport ( 0.000754034082340427 ); GO:0046831 regulation of RNA export from nucleus ( 0.000754034082340427 ); GO:0046833 positive regulation of RNA export from nucleus ( 0.000754034082340427 ); GO:0015631 tubulin binding ( 0.00104136419473703 ); GO:0006408 snRNA export from nucleus ( 0.00150753747509946 ); GO:0051030 snRNA transport ( 0.00150753747509946 ); GO:0005845 mRNA cap binding complex ( 0.00150753747509946 ); GO:0034518 RNA cap binding complex ( 0.00150753747509946 ); GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity ( 0.00226051052511589 ); GO:0006290 pyrimidine dimer repair ( 0.00301295357901865 ); GO:0008092 cytoskeletal protein binding ( 0.00361479614542447 ); GO:0046686 response to cadmium ion ( 0.00376486698322753 ); GO:0046688 response to copper ion ( 0.00376486698322753 ); GO:0000339 RNA cap binding ( 0.00526710622720084 ); GO:0008171 O-methyltransferase activity ( 0.00526710622720084 ); GO:0006878 cellular copper ion homeostasis ( 0.00676723102421728 ); GO:0042147 retrograde transport, endosome to Golgi ( 0.00751650136894899 ); GO:0055070 copper ion homeostasis ( 0.00751650136894899 ); GO:0031201 SNARE complex ( 0.00751650136894899 ); GO:0006916 anti-apoptosis ( 0.00757667396081684 ); ----------------KEGG-------------- hsa05060 Prion disease ( 0.00976114832942221 ); hsa03410 Base excision repair ( 0.0253415077537568 ); hsa04130 SNARE interactions in vesicular transport ( 0.0282831308946448 ); hsa00480 Glutathione metabolism ( 0.0370583594674845 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0457595805527525 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0472026296759908 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0196389731235503 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3049 ========================= ----------------C2-------------- KEGG_HUNTINGTONS_DISEASE ( 0.00708591056164108 ); BIOCARTA_ETC_PATHWAY ( 0.00826524413812157 ); REACTOME_UNWINDING_OF_DNA ( 0.00826524413812157 ); ----------------C3-------------- CAGCAGG,MIR-370 ( 0.00420866213931768 ); V$LFA1_Q6 ( 0.00834102529007705 ); V$ERR1_Q2 ( 0.0087801530407231 ); V$ER_Q6_02 ( 0.0096891038535967 ); ----------------C4-------------- GNF2_CDC2 ( 0.000798262040819534 ); GNF2_CENPF ( 0.000798262040819534 ); MORF_EIF4E ( 0.00146449672782771 ); module_18 ( 0.0038347621916221 ); MORF_RPA2 ( 0.00700559024739092 ); MORF_DAP3 ( 0.00757667396081684 ); ----------------C5-------------- NUCLEAR_LUMEN ( 0.00242161807661699 ); ORGANELLE_LUMEN ( 0.00393511571732543 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00393511571732543 ); NUCLEAR_PART ( 0.00724067280794122 ); INTRACELLULAR_ORGANELLE_PART ( 0.00891188462958628 ); DNA_DIRECTED_RNA_POLYMERASE_II__CORE_COMPLEX ( 0.00901345967669576 ); ORGANELLE_PART ( 0.0090483707504084 ); ----------------GOSLIM-------------- GO:0004161 dimethylallyltranstransferase activity ( ); GO:0004337 geranyltranstransferase activity ( ); GO:0047134 protein-disulfide reductase activity ( ); GO:0000320 re-entry into mitotic cell cycle ( ); GO:0048096 chromatin-mediated maintenance of transcription ( ); GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c ( ); GO:0008121 ubiquinol-cytochrome-c reductase activity ( ); GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors ( ); GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor ( ); GO:0045815 positive regulation of gene expression, epigenetic ( ); GO:0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor ( ); GO:0033209 tumor necrosis factor-mediated signaling pathway ( ); GO:0016514 SWI/SNF complex ( ); ----------------GO-------------- GO:0004161 dimethylallyltranstransferase activity ( 0.00150753747509946 ); GO:0004337 geranyltranstransferase activity ( 0.00150753747509946 ); GO:0047134 protein-disulfide reductase activity ( 0.00150753747509946 ); GO:0000320 re-entry into mitotic cell cycle ( 0.00301295357901865 ); GO:0048096 chromatin-mediated maintenance of transcription ( 0.00301295357901865 ); GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c ( 0.00376486698322753 ); GO:0008121 ubiquinol-cytochrome-c reductase activity ( 0.00451625108395437 ); GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors ( 0.00451625108395437 ); GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor ( 0.00451625108395437 ); GO:0045815 positive regulation of gene expression, epigenetic ( 0.00526710622720084 ); GO:0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor ( 0.0060174327587601 ); GO:0033209 tumor necrosis factor-mediated signaling pathway ( 0.00676723102421728 ); GO:0016514 SWI/SNF complex ( 0.00901345967669576 ); ----------------KEGG-------------- hsa00900 Terpenoid biosynthesis ( 0.00451625108395437 ); hsa00100 Biosynthesis of steroids ( 0.0179510474342097 ); hsa03020 RNA polymerase ( 0.0186924402717202 ); ----------------CARTA-------------- il2pathway ( 0.0142362349228341 ); rac1pathway ( 0.014980245010193 ); eif4pathway ( 0.0179510474342097 ); ptenpathway ( 0.019433310686252 ); mtorpathway ( 0.0312164661110346 ); il2rbpathway ( 0.0312164661110346 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.000155499774277609 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0256631346698016 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0313535843974414 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3090 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$GATA1_03 ( 0.00034221861700215 ); GTTAAAG,MIR-302B ( 0.000885742534555137 ); ATATGCA,MIR-448 ( 0.00661033970394564 ); V$TCF1P_Q6 ( 0.00782771283832003 ); ----------------C4-------------- ( 0.00218208340012046 ); ----------------C5-------------- ANTIPORTER_ACTIVITY ( 0.00751650136894899 ); PROTEIN_POLYUBIQUITINATION ( 0.00826524413812157 ); ----------------GOSLIM-------------- GO:0006566 threonine metabolic process ( ); GO:0009088 threonine biosynthetic process ( ); GO:0004795 threonine synthase activity ( ); GO:0008747 N-acetylneuraminate lyase activity ( ); GO:0009309 amine biosynthetic process ( ); GO:0004765 shikimate kinase activity ( ); GO:0016838 carbon-oxygen lyase activity, acting on phosphates ( ); GO:0042978 ornithine decarboxylase activator activity ( ); GO:0044271 nitrogen compound biosynthetic process ( ); GO:0008073 ornithine decarboxylase inhibitor activity ( ); GO:0016833 oxo-acid-lyase activity ( ); GO:0006596 polyamine biosynthetic process ( ); GO:0042979 ornithine decarboxylase regulator activity ( ); GO:0016829 lyase activity ( ); GO:0006595 polyamine metabolic process ( ); GO:0005451 monovalent cation:proton antiporter activity ( ); GO:0015385 sodium:hydrogen antiporter activity ( ); ----------------GO-------------- GO:0006566 threonine metabolic process ( 0.000754034082340427 ); GO:0009088 threonine biosynthetic process ( 0.000754034082340427 ); GO:0004795 threonine synthase activity ( 0.000754034082340427 ); GO:0008747 N-acetylneuraminate lyase activity ( 0.000754034082340427 ); GO:0009309 amine biosynthetic process ( 0.00114060079307206 ); GO:0004765 shikimate kinase activity ( 0.00150753747509946 ); GO:0016838 carbon-oxygen lyase activity, acting on phosphates ( 0.00150753747509946 ); GO:0042978 ornithine decarboxylase activator activity ( 0.00226051052511589 ); GO:0044271 nitrogen compound biosynthetic process ( 0.00246790296198645 ); GO:0008073 ornithine decarboxylase inhibitor activity ( 0.00301295357901865 ); GO:0016833 oxo-acid-lyase activity ( 0.00376486698322753 ); GO:0006596 polyamine biosynthetic process ( 0.00451625108395437 ); GO:0042979 ornithine decarboxylase regulator activity ( 0.00451625108395437 ); GO:0016829 lyase activity ( 0.00486256670327533 ); GO:0006595 polyamine metabolic process ( 0.00676723102421728 ); GO:0005451 monovalent cation:proton antiporter activity ( 0.00676723102421728 ); GO:0015385 sodium:hydrogen antiporter activity ( 0.00676723102421728 ); ----------------KEGG-------------- ( 0.0223915749484692 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.011426747319934 ); ============================ group2997 ========================= ----------------C2-------------- KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION ( 0.002930331373038 ); KEGG_TIGHT_JUNCTION ( 0.00377411684039092 ); REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS ( 0.0098109591368496 ); ----------------C3-------------- ( 0.00789213553208199 ); ----------------C4-------------- module_26 ( 0.00675061517774531 ); module_389 ( 0.00697233587830485 ); module_379 ( 0.00781348616863882 ); module_207 ( 0.00797114636986265 ); module_242 ( 0.00861618959146791 ); ----------------C5-------------- INTERCELLULAR_JUNCTION ( 0.000932725716290043 ); CELL_JUNCTION ( 0.00140850859256253 ); NEGATIVE_REGULATION_OF_CELL_PROLIFERATION ( 0.0049693894861896 ); SECRETIN_LIKE_RECEPTOR_ACTIVITY ( 0.00701698780579418 ); PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.00841488724583639 ); EXTRINSIC_TO_PLASMA_MEMBRANE ( 0.0091131514970586 ); ----------------GOSLIM-------------- GO:0004512 inositol-3-phosphate synthase activity ( ); GO:0016872 intramolecular lyase activity ( ); GO:0050201 fucokinase activity ( ); GO:0021938 smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation ( ); GO:0016527 brain-specific angiogenesis inhibitor activity ( ); GO:0006021 inositol biosynthetic process ( ); GO:0021937 Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation ( ); GO:0005883 neurofilament ( ); GO:0030054 cell junction ( ); GO:0046173 polyol biosynthetic process ( ); GO:0060053 neurofilament cytoskeleton ( ); GO:0002052 positive regulation of neuroblast proliferation ( ); GO:0021936 regulation of granule cell precursor proliferation ( ); GO:0021940 positive regulation of granule cell precursor proliferation ( ); GO:0021534 cell proliferation in hindbrain ( ); GO:0021924 cell proliferation in the external granule layer ( ); GO:0021930 granule cell precursor proliferation ( ); GO:0021696 cerebellar cortex morphogenesis ( ); GO:0042127 regulation of cell proliferation ( ); GO:0006020 inositol metabolic process ( ); GO:0021587 cerebellum morphogenesis ( ); GO:0004926 non-G-protein coupled 7TM receptor activity ( ); GO:0021575 hindbrain morphogenesis ( ); GO:0021695 cerebellar cortex development ( ); GO:0001755 neural crest cell migration ( ); GO:0042307 positive regulation of protein import into nucleus ( ); ----------------GO-------------- GO:0004512 inositol-3-phosphate synthase activity ( 0.000703765143517776 ); GO:0016872 intramolecular lyase activity ( 0.000703765143517776 ); GO:0050201 fucokinase activity ( 0.000703765143517776 ); GO:0021938 smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation ( 0.00210991591511245 ); GO:0016527 brain-specific angiogenesis inhibitor activity ( 0.00210991591511245 ); GO:0006021 inositol biosynthetic process ( 0.00281230209797756 ); GO:0021937 Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation ( 0.00281230209797756 ); GO:0005883 neurofilament ( 0.00351422918182487 ); GO:0030054 cell junction ( 0.0037432000660514 ); GO:0046173 polyol biosynthetic process ( 0.00421569744366379 ); GO:0060053 neurofilament cytoskeleton ( 0.00421569744366379 ); GO:0002052 positive regulation of neuroblast proliferation ( 0.00491670716035253 ); GO:0021936 regulation of granule cell precursor proliferation ( 0.00491670716035253 ); GO:0021940 positive regulation of granule cell precursor proliferation ( 0.00491670716035253 ); GO:0021534 cell proliferation in hindbrain ( 0.00561725860859474 ); GO:0021924 cell proliferation in the external granule layer ( 0.00561725860859474 ); GO:0021930 granule cell precursor proliferation ( 0.00561725860859474 ); GO:0021696 cerebellar cortex morphogenesis ( 0.00631735206494322 ); GO:0042127 regulation of cell proliferation ( 0.00656619172561789 ); GO:0006020 inositol metabolic process ( 0.00771616610739456 ); GO:0021587 cerebellum morphogenesis ( 0.00771616610739456 ); GO:0004926 non-G-protein coupled 7TM receptor activity ( 0.00771616610739456 ); GO:0021575 hindbrain morphogenesis ( 0.00841488724583639 ); GO:0021695 cerebellar cortex development ( 0.00841488724583639 ); GO:0001755 neural crest cell migration ( 0.0098109591368496 ); GO:0042307 positive regulation of protein import into nucleus ( 0.0098109591368496 ); ----------------KEGG-------------- hsa04670 Leukocyte transendothelial migration ( 0.002930331373038 ); hsa04530 Tight junction ( 0.00377411684039092 ); hsa00051 Fructose and mannose metabolism ( 0.0243599291322284 ); hsa00562 Inositol phosphate metabolism ( 0.0332666941618391 ); hsa05217 Basal cell carcinoma ( 0.0380313127801409 ); hsa04340 Hedgehog signaling pathway ( 0.0393886218534578 ); hsa04115 p53 signaling pathway ( 0.0461485326015025 ); ----------------CARTA-------------- gata3pathway ( 0.0105083104408434 ); her2pathway ( 0.0146828506293769 ); pgc1apathway ( 0.0167639824701413 ); il10pathway ( 0.0167639824701413 ); hcmvpathway ( 0.0209140066703924 ); mtorpathway ( 0.0291653037163513 ); mapkpathway ( 0.0312180143383668 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3057 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.0091131514970586 ); ----------------C5-------------- ( 0.00701698780579418 ); ----------------GOSLIM-------------- GO:0006419 alanyl-tRNA aminoacylation ( ); GO:0004813 alanine-tRNA ligase activity ( ); GO:0050785 advanced glycation end-product receptor activity ( ); GO:0005451 monovalent cation:proton antiporter activity ( ); GO:0015385 sodium:hydrogen antiporter activity ( ); GO:0007420 brain development ( ); ----------------GO-------------- GO:0006419 alanyl-tRNA aminoacylation ( 0.00210991591511245 ); GO:0004813 alanine-tRNA ligase activity ( 0.00210991591511245 ); GO:0050785 advanced glycation end-product receptor activity ( 0.00210991591511245 ); GO:0005451 monovalent cation:proton antiporter activity ( 0.00631735206494322 ); GO:0015385 sodium:hydrogen antiporter activity ( 0.00631735206494322 ); GO:0007420 brain development ( 0.00697233587830485 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3095 ========================= ----------------C2-------------- BIOCARTA_P35ALZHEIMERS_PATHWAY ( 0.00771616610739456 ); BIOCARTA_CDK5_PATHWAY ( 0.00771616610739456 ); BIOCARTA_RB_PATHWAY ( 0.00841488724583639 ); ----------------C3-------------- GGGYGTGNY_UNKNOWN ( 0.000278661764802494 ); V$CREB_Q3 ( 0.00734920743281539 ); ----------------C4-------------- ( ); ----------------C5-------------- NEURITE_DEVELOPMENT ( 0.000620918738470302 ); NEURON_DEVELOPMENT ( 0.000821939742188436 ); NEURON_DIFFERENTIATION ( 0.00127237583690095 ); GENERATION_OF_NEURONS ( 0.00151499357339963 ); NEUROGENESIS ( 0.00189690035936443 ); CELL_PROLIFERATION_GO_0008283 ( 0.00449179881346929 ); TRANSCRIPTION_ACTIVATOR_ACTIVITY ( 0.00603557810312095 ); CELL_SOMA ( 0.00701698780579418 ); GROWTH_CONE ( 0.00701698780579418 ); REGULATION_OF_SYNAPSE_STRUCTURE_AND_ACTIVITY ( 0.00701698780579418 ); INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_BINDING ( 0.00701698780579418 ); STEROID_HORMONE_RECEPTOR_BINDING ( 0.00701698780579418 ); SITE_OF_POLARIZED_GROWTH ( 0.00771616610739456 ); AXON ( 0.00841488724583639 ); INTRA_GOLGI_VESICLE_MEDIATED_TRANSPORT ( 0.00841488724583639 ); REGULATION_OF_NEURON_APOPTOSIS ( 0.00841488724583639 ); G1_PHASE_OF_MITOTIC_CELL_CYCLE ( 0.0091131514970586 ); POSITIVE_REGULATION_OF_CELLULAR_PROCESS ( 0.00925500529664731 ); REGULATION_OF_NEUROGENESIS ( 0.0098109591368496 ); ----------------GOSLIM-------------- GO:0006713 glucocorticoid catabolic process ( ); GO:0009794 regulation of mitotic cell cycle, embryonic ( ); GO:0031914 negative regulation of synaptic plasticity ( ); GO:0033136 serine phosphorylation of STAT3 protein ( ); GO:0042501 serine phosphorylation of STAT protein ( ); GO:0045448 mitotic cell cycle, embryonic ( ); GO:0045956 positive regulation of calcium ion-dependent exocytosis ( ); GO:0021801 cerebral cortex radial glia guided migration ( ); GO:0021819 layer formation in the cerebral cortex ( ); GO:0022038 corpus callosum development ( ); GO:0046826 negative regulation of protein export from nucleus ( ); GO:0017158 regulation of calcium ion-dependent exocytosis ( ); GO:0014044 Schwann cell development ( ); GO:0021799 cerebral cortex radially oriented cell migration ( ); GO:0043113 receptor clustering ( ); GO:0060079 regulation of excitatory postsynaptic membrane potential ( ); GO:0035259 glucocorticoid receptor binding ( ); GO:0014073 response to tropane ( ); GO:0031397 negative regulation of protein ubiquitination ( ); GO:0032801 receptor catabolic process ( ); GO:0042220 response to cocaine ( ); GO:0046825 regulation of protein export from nucleus ( ); GO:0048148 behavioral response to cocaine ( ); GO:0014037 Schwann cell differentiation ( ); GO:0021795 cerebral cortex cell migration ( ); GO:0045921 positive regulation of exocytosis ( ); GO:0060078 regulation of postsynaptic membrane potential ( ); GO:0002039 p53 binding ( ); GO:0021697 cerebellar cortex formation ( ); GO:0031958 corticosteroid receptor signaling pathway ( ); GO:0042921 glucocorticoid receptor signaling pathway ( ); GO:0045176 apical protein localization ( ); GO:0045995 regulation of embryonic development ( ); GO:0022029 telencephalon cell migration ( ); GO:0042447 hormone catabolic process ( ); GO:0048813 dendrite morphogenesis ( ); GO:0008045 motor axon guidance ( ); GO:0008306 associative learning ( ); GO:0021696 cerebellar cortex morphogenesis ( ); GO:0021885 forebrain cell migration ( ); GO:0007420 brain development ( ); GO:0008105 asymmetric protein localization ( ); GO:0008211 glucocorticoid metabolic process ( ); GO:0021587 cerebellum morphogenesis ( ); GO:0035249 synaptic transmission, glutamatergic ( ); GO:0001963 synaptic transmission, dopaminergic ( ); GO:0007172 signal complex assembly ( ); GO:0021575 hindbrain morphogenesis ( ); GO:0021695 cerebellar cortex development ( ); GO:0021766 hippocampus development ( ); GO:0000080 G1 phase of mitotic cell cycle ( ); GO:0017157 regulation of exocytosis ( ); GO:0030175 filopodium ( ); ----------------GO-------------- GO:0006713 glucocorticoid catabolic process ( 0.000703765143517776 ); GO:0009794 regulation of mitotic cell cycle, embryonic ( 0.000703765143517776 ); GO:0031914 negative regulation of synaptic plasticity ( 0.000703765143517776 ); GO:0033136 serine phosphorylation of STAT3 protein ( 0.000703765143517776 ); GO:0042501 serine phosphorylation of STAT protein ( 0.000703765143517776 ); GO:0045448 mitotic cell cycle, embryonic ( 0.000703765143517776 ); GO:0045956 positive regulation of calcium ion-dependent exocytosis ( 0.000703765143517776 ); GO:0021801 cerebral cortex radial glia guided migration ( 0.00140707035606513 ); GO:0021819 layer formation in the cerebral cortex ( 0.00140707035606513 ); GO:0022038 corpus callosum development ( 0.00140707035606513 ); GO:0046826 negative regulation of protein export from nucleus ( 0.00140707035606513 ); GO:0017158 regulation of calcium ion-dependent exocytosis ( 0.00210991591511245 ); GO:0014044 Schwann cell development ( 0.00281230209797756 ); GO:0021799 cerebral cortex radially oriented cell migration ( 0.00281230209797756 ); GO:0043113 receptor clustering ( 0.00281230209797756 ); GO:0060079 regulation of excitatory postsynaptic membrane potential ( 0.00281230209797756 ); GO:0035259 glucocorticoid receptor binding ( 0.00281230209797756 ); GO:0014073 response to tropane ( 0.00351422918182487 ); GO:0031397 negative regulation of protein ubiquitination ( 0.00351422918182487 ); GO:0032801 receptor catabolic process ( 0.00351422918182487 ); GO:0042220 response to cocaine ( 0.00351422918182487 ); GO:0046825 regulation of protein export from nucleus ( 0.00351422918182487 ); GO:0048148 behavioral response to cocaine ( 0.00351422918182487 ); GO:0014037 Schwann cell differentiation ( 0.00421569744366379 ); GO:0021795 cerebral cortex cell migration ( 0.00421569744366379 ); GO:0045921 positive regulation of exocytosis ( 0.00421569744366379 ); GO:0060078 regulation of postsynaptic membrane potential ( 0.00421569744366379 ); GO:0002039 p53 binding ( 0.00421569744366379 ); GO:0021697 cerebellar cortex formation ( 0.00491670716035253 ); GO:0031958 corticosteroid receptor signaling pathway ( 0.00491670716035253 ); GO:0042921 glucocorticoid receptor signaling pathway ( 0.00491670716035253 ); GO:0045176 apical protein localization ( 0.00491670716035253 ); GO:0045995 regulation of embryonic development ( 0.00491670716035253 ); GO:0022029 telencephalon cell migration ( 0.00561725860859474 ); GO:0042447 hormone catabolic process ( 0.00561725860859474 ); GO:0048813 dendrite morphogenesis ( 0.00561725860859474 ); GO:0008045 motor axon guidance ( 0.00631735206494322 ); GO:0008306 associative learning ( 0.00631735206494322 ); GO:0021696 cerebellar cortex morphogenesis ( 0.00631735206494322 ); GO:0021885 forebrain cell migration ( 0.00631735206494322 ); GO:0007420 brain development ( 0.00697233587830485 ); GO:0008105 asymmetric protein localization ( 0.00701698780579418 ); GO:0008211 glucocorticoid metabolic process ( 0.00771616610739456 ); GO:0021587 cerebellum morphogenesis ( 0.00771616610739456 ); GO:0035249 synaptic transmission, glutamatergic ( 0.00771616610739456 ); GO:0001963 synaptic transmission, dopaminergic ( 0.00841488724583639 ); GO:0007172 signal complex assembly ( 0.00841488724583639 ); GO:0021575 hindbrain morphogenesis ( 0.00841488724583639 ); GO:0021695 cerebellar cortex development ( 0.00841488724583639 ); GO:0021766 hippocampus development ( 0.00841488724583639 ); GO:0000080 G1 phase of mitotic cell cycle ( 0.0098109591368496 ); GO:0017157 regulation of exocytosis ( 0.0098109591368496 ); GO:0030175 filopodium ( 0.0098109591368496 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- p38mapkpathway ( 0.000389681102439087 ); classicpathway ( 0.00281230209797756 ); s1ppathway ( 0.00421569744366379 ); lectinpathway ( 0.00561725860859474 ); mprpathway ( 0.0105083104408434 ); myosinpathway ( 0.0139882315603812 ); g2pathway ( 0.0188410320195301 ); il2rbpathway ( 0.0291653037163513 ); fcer1pathway ( 0.0339486929666634 ); ----------------RBP-------------- ( 0.0117608646190868 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3140 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00697233587830485 ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.0091131514970586 ); ----------------GOSLIM-------------- GO:0006730 one-carbon compound metabolic process ( ); GO:0031167 rRNA methylation ( ); GO:0000154 rRNA modification ( ); GO:0001510 RNA methylation ( ); GO:0050690 regulation of defense response to virus by virus ( ); GO:0050684 regulation of mRNA processing ( ); GO:0042101 T cell receptor complex ( ); GO:0042288 MHC class I protein binding ( ); GO:0050688 regulation of defense response to virus ( ); ----------------GO-------------- GO:0006730 one-carbon compound metabolic process ( 0.00133960516423991 ); GO:0031167 rRNA methylation ( 0.00281230209797756 ); GO:0000154 rRNA modification ( 0.00421569744366379 ); GO:0001510 RNA methylation ( 0.00561725860859474 ); GO:0050690 regulation of defense response to virus by virus ( 0.00561725860859474 ); GO:0050684 regulation of mRNA processing ( 0.00841488724583639 ); GO:0042101 T cell receptor complex ( 0.00841488724583639 ); GO:0042288 MHC class I protein binding ( 0.0091131514970586 ); GO:0050688 regulation of defense response to virus ( 0.0098109591368496 ); ----------------KEGG-------------- hsa00910 Nitrogen metabolism ( 0.0167639824701413 ); hsa05340 Primary immunodeficiency ( 0.0243599291322284 ); ----------------CARTA-------------- ( 0.00140707035606513 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3161 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$GATA_C ( 0.00861618959146791 ); V$LYF1_01 ( 0.0087810321931554 ); ----------------C4-------------- module_560 ( 0.00771616610739456 ); module_190 ( 0.00841488724583639 ); ----------------C5-------------- CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.00318313701633802 ); BILE_ACID_METABOLIC_PROCESS ( 0.00771616610739456 ); NEGATIVE_REGULATION_OF_PHOSPHORYLATION ( 0.00841488724583639 ); PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.00841488724583639 ); NEGATIVE_REGULATION_OF_CELLULAR_PROCESS ( 0.00859665006093658 ); NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS ( 0.0091131514970586 ); NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS ( 0.00973732872772897 ); STRIATED_MUSCLE_CONTRACTION_GO_0006941 ( 0.0098109591368496 ); ----------------GOSLIM-------------- GO:0006680 glucosylceramide catabolic process ( 0.00637480045131413 ); GO:0016140 O-glycoside metabolic process ( 0.00637480045131413 ); GO:0016142 O-glycoside catabolic process ( 0.00637480045131413 ); GO:0050827 toxin receptor binding ( 0.00637480045131413 ); GO:0042692 muscle cell differentiation ( 0.00637480045131413 ); GO:0048523 negative regulation of cellular process ( 0.00637480045131413 ); GO:0016137 glycoside metabolic process ( 0.00637480045131413 ); GO:0016139 glycoside catabolic process ( 0.00637480045131413 ); GO:0004348 glucosylceramidase activity ( 0.00637480045131413 ); GO:0008160 protein tyrosine phosphatase activator activity ( 0.00637480045131413 ); GO:0048519 negative regulation of biological process ( 0.00637480045131413 ); GO:0009404 toxin metabolic process ( 0.00637480045131413 ); GO:0014912 negative regulation of smooth muscle cell migration ( 0.00637480045131413 ); GO:0045663 positive regulation of myoblast differentiation ( 0.00637480045131413 ); GO:0046477 glycosylceramide catabolic process ( 0.00637480045131413 ); GO:0008422 beta-glucosidase activity ( 0.00637480045131413 ); GO:0019211 phosphatase activator activity ( 0.00637480045131413 ); GO:0006678 glucosylceramide metabolic process ( 0.00637480045131413 ); GO:0046514 ceramide catabolic process ( 0.00637480045131413 ); GO:0016942 insulin-like growth factor binding protein complex ( 0.00637480045131413 ); GO:0004500 dopamine beta-monooxygenase activity ( 0.00637480045131413 ); GO:0001558 regulation of cell growth ( 0.00637480045131413 ); GO:0046521 sphingoid catabolic process ( 0.00637480045131413 ); GO:0051149 positive regulation of muscle cell differentiation ( 0.00637480045131413 ); GO:0055003 cardiac myofibril assembly ( 0.00637480045131413 ); GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ( 0.00637480045131413 ); GO:0031994 insulin-like growth factor I binding ( 0.00637480045131413 ); GO:0032036 myosin heavy chain binding ( 0.00637480045131413 ); GO:0014706 striated muscle development ( 0.00637480045131413 ); GO:0031324 negative regulation of cellular metabolic process ( 0.00637480045131413 ); GO:0010605 negative regulation of macromolecule metabolic process ( 0.00637480045131413 ); GO:0006677 glycosylceramide metabolic process ( 0.00637480045131413 ); GO:0019377 glycolipid catabolic process ( 0.00637480045131413 ); GO:0003785 actin monomer binding ( 0.00637480045131413 ); GO:0016049 cell growth ( 0.00637480045131413 ); GO:0016042 lipid catabolic process ( 0.00637480045131413 ); GO:0014910 regulation of smooth muscle cell migration ( 0.00637480045131413 ); GO:0045661 regulation of myoblast differentiation ( 0.00637480045131413 ); GO:0048662 negative regulation of smooth muscle cell proliferation ( 0.00637480045131413 ); GO:0005790 smooth endoplasmic reticulum ( 0.00637480045131413 ); GO:0015926 glucosidase activity ( 0.00637480045131413 ); GO:0017040 ceramidase activity ( 0.00637480045131413 ); GO:0008361 regulation of cell size ( 0.00637480045131413 ); GO:0009892 negative regulation of metabolic process ( 0.00637480045131413 ); GO:0006548 histidine catabolic process ( 0.00637480045131413 ); GO:0009077 histidine family amino acid catabolic process ( 0.00637480045131413 ); GO:0014909 smooth muscle cell migration ( 0.00637480045131413 ); GO:0055013 cardiac muscle cell development ( 0.00637480045131413 ); GO:0014812 muscle cell migration ( 0.00637480045131413 ); GO:0006547 histidine metabolic process ( 0.00637480045131413 ); GO:0009075 histidine family amino acid metabolic process ( 0.00637480045131413 ); GO:0007517 muscle development ( 0.00637480045131413 ); GO:0001933 negative regulation of protein amino acid phosphorylation ( 0.00637480045131413 ); GO:0048742 regulation of skeletal muscle fiber development ( 0.00637480045131413 ); GO:0008206 bile acid metabolic process ( 0.00637480045131413 ); ----------------GO-------------- GO:0006680 glucosylceramide catabolic process ( 0.000703765143517776 ); GO:0016140 O-glycoside metabolic process ( 0.000703765143517776 ); GO:0016142 O-glycoside catabolic process ( 0.000703765143517776 ); GO:0050827 toxin receptor binding ( 0.000703765143517776 ); GO:0042692 muscle cell differentiation ( 0.00111165408223902 ); GO:0048523 negative regulation of cellular process ( 0.00115412871133651 ); GO:0016137 glycoside metabolic process ( 0.00140707035606513 ); GO:0016139 glycoside catabolic process ( 0.00140707035606513 ); GO:0004348 glucosylceramidase activity ( 0.00140707035606513 ); GO:0008160 protein tyrosine phosphatase activator activity ( 0.00140707035606513 ); GO:0048519 negative regulation of biological process ( 0.00163183016288298 ); GO:0009404 toxin metabolic process ( 0.00210991591511245 ); GO:0014912 negative regulation of smooth muscle cell migration ( 0.00210991591511245 ); GO:0045663 positive regulation of myoblast differentiation ( 0.00210991591511245 ); GO:0046477 glycosylceramide catabolic process ( 0.00210991591511245 ); GO:0008422 beta-glucosidase activity ( 0.00210991591511245 ); GO:0019211 phosphatase activator activity ( 0.00210991591511245 ); GO:0006678 glucosylceramide metabolic process ( 0.00281230209797756 ); GO:0046514 ceramide catabolic process ( 0.00281230209797756 ); GO:0016942 insulin-like growth factor binding protein complex ( 0.00281230209797756 ); GO:0004500 dopamine beta-monooxygenase activity ( 0.00281230209797756 ); GO:0001558 regulation of cell growth ( 0.0033925222704781 ); GO:0046521 sphingoid catabolic process ( 0.00351422918182487 ); GO:0051149 positive regulation of muscle cell differentiation ( 0.00351422918182487 ); GO:0055003 cardiac myofibril assembly ( 0.00351422918182487 ); GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ( 0.00351422918182487 ); GO:0031994 insulin-like growth factor I binding ( 0.00351422918182487 ); GO:0032036 myosin heavy chain binding ( 0.00351422918182487 ); GO:0014706 striated muscle development ( 0.00360822009017299 ); GO:0031324 negative regulation of cellular metabolic process ( 0.00469878535454646 ); GO:0010605 negative regulation of macromolecule metabolic process ( 0.00475143046371682 ); GO:0006677 glycosylceramide metabolic process ( 0.00491670716035253 ); GO:0019377 glycolipid catabolic process ( 0.00491670716035253 ); GO:0003785 actin monomer binding ( 0.00491670716035253 ); GO:0016049 cell growth ( 0.00503318815054671 ); GO:0016042 lipid catabolic process ( 0.0051619270594062 ); GO:0014910 regulation of smooth muscle cell migration ( 0.00561725860859474 ); GO:0045661 regulation of myoblast differentiation ( 0.00561725860859474 ); GO:0048662 negative regulation of smooth muscle cell proliferation ( 0.00561725860859474 ); GO:0005790 smooth endoplasmic reticulum ( 0.00561725860859474 ); GO:0015926 glucosidase activity ( 0.00561725860859474 ); GO:0017040 ceramidase activity ( 0.00561725860859474 ); GO:0008361 regulation of cell size ( 0.0056244486360143 ); GO:0009892 negative regulation of metabolic process ( 0.00564336487347788 ); GO:0006548 histidine catabolic process ( 0.00631735206494322 ); GO:0009077 histidine family amino acid catabolic process ( 0.00631735206494322 ); GO:0014909 smooth muscle cell migration ( 0.00631735206494322 ); GO:0055013 cardiac muscle cell development ( 0.00631735206494322 ); GO:0014812 muscle cell migration ( 0.00701698780579418 ); GO:0006547 histidine metabolic process ( 0.00771616610739456 ); GO:0009075 histidine family amino acid metabolic process ( 0.00771616610739456 ); GO:0007517 muscle development ( 0.00781348616863882 ); GO:0001933 negative regulation of protein amino acid phosphorylation ( 0.0091131514970586 ); GO:0048742 regulation of skeletal muscle fiber development ( 0.0091131514970586 ); GO:0008206 bile acid metabolic process ( 0.0098109591368496 ); ----------------KEGG-------------- hsa05050 Dentatorubropallidoluysian atrophy (DRPLA) ( 0.0098109591368496 ); hsa00561 Glycerolipid metabolism ( 0.0346302449873479 ); hsa04115 p53 signaling pathway ( 0.0461485326015025 ); ----------------CARTA-------------- p53pathway ( 0.00561725860859474 ); mta3pathway ( 0.0112052056845211 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3305 ========================= ----------------C2-------------- ( ); ----------------C3-------------- GCAAAAA,MIR-129 ( 0.00014676770902812 ); V$HFH3_01 ( 0.000158561548158406 ); V$HFH1_01 ( 0.000280032558141778 ); CTCAGGG,MIR-125B,MIR-125A ( 0.000858597542396104 ); TCTGGAC,MIR-198 ( 0.00105031697991553 ); ATGCAGT,MIR-217 ( 0.00181721639514901 ); CTCTGGA,MIR-520A,MIR-525 ( 0.00349958411026115 ); V$FOXJ2_01 ( 0.00459461938333023 ); V$RSRFC4_Q2 ( 0.00589703616725478 ); V$FOX_Q2 ( 0.00596612019045175 ); V$HNF3B_01 ( 0.00624619035381494 ); V$MEF2_03 ( 0.00712198632548189 ); V$IPF1_Q4 ( 0.00712198632548189 ); V$STAT5B_01 ( 0.00742567801528243 ); V$RSRFC4_01 ( 0.00765727375484107 ); V$AREB6_04 ( 0.00797114636986265 ); V$FREAC2_01 ( 0.00805051820996742 ); AAAYWAACM_V$HFH4_01 ( 0.00821034301111664 ); V$HNF4ALPHA_Q6 ( 0.00845277595316452 ); V$CEBP_01 ( 0.0087810321931554 ); ----------------C4-------------- ( ); ----------------C5-------------- FUCOSYLTRANSFERASE_ACTIVITY ( 0.00701698780579418 ); OLIGOSACCHARIDE_METABOLIC_PROCESS ( 0.00771616610739456 ); ----------------GOSLIM-------------- GO:0033578 protein amino acid glycosylation in Golgi ( ); GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity ( ); GO:0046921 alpha(1,6)-fucosyltransferase activity ( ); GO:0017124 SH3 domain binding ( ); GO:0004499 flavin-containing monooxygenase activity ( ); GO:0032580 Golgi cisterna membrane ( ); GO:0006491 N-glycan processing ( ); GO:0009312 oligosaccharide biosynthetic process ( ); GO:0019317 fucose catabolic process ( ); GO:0042355 L-fucose catabolic process ( ); GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor ( ); GO:0042354 L-fucose metabolic process ( ); GO:0004198 calcium-dependent cysteine-type endopeptidase activity ( ); GO:0008417 fucosyltransferase activity ( ); GO:0019904 protein domain specific binding ( ); ----------------GO-------------- GO:0033578 protein amino acid glycosylation in Golgi ( 0.000703765143517776 ); GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity ( 0.000703765143517776 ); GO:0046921 alpha(1,6)-fucosyltransferase activity ( 0.000703765143517776 ); GO:0017124 SH3 domain binding ( 0.00155132111384024 ); GO:0004499 flavin-containing monooxygenase activity ( 0.00351422918182487 ); GO:0032580 Golgi cisterna membrane ( 0.00561725860859474 ); GO:0006491 N-glycan processing ( 0.00631735206494322 ); GO:0009312 oligosaccharide biosynthetic process ( 0.00631735206494322 ); GO:0019317 fucose catabolic process ( 0.00631735206494322 ); GO:0042355 L-fucose catabolic process ( 0.00631735206494322 ); GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor ( 0.00701698780579418 ); GO:0042354 L-fucose metabolic process ( 0.00771616610739456 ); GO:0004198 calcium-dependent cysteine-type endopeptidase activity ( 0.0098109591368496 ); GO:0008417 fucosyltransferase activity ( 0.0098109591368496 ); GO:0019904 protein domain specific binding ( 0.00988708202380397 ); ----------------KEGG-------------- hsa00533 Keratan sulfate biosynthesis ( 0.0112052056845211 ); hsa00510 N-Glycan biosynthesis ( 0.0291653037163513 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0441252119772407 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group25 ========================= ----------------C2-------------- ( ); ----------------C3-------------- MGGAAGTG_V$GABP_B ( 0.00393314440136946 ); V$NRF2_01 ( 0.00514204648517372 ); V$AP2GAMMA_01 ( 0.00569407379732279 ); ----------------C4-------------- ( 0.00586729198586211 ); ----------------C5-------------- ( 0.00716681172756617 ); ----------------GOSLIM-------------- GO:0021570 rhombomere 4 development ( ); GO:0021754 facial nucleus development ( ); GO:0006853 carnitine shuttle ( ); GO:0021561 facial nerve development ( ); GO:0021569 rhombomere 3 development ( ); GO:0021604 cranial nerve structural organization ( ); GO:0021610 facial nerve morphogenesis ( ); GO:0021612 facial nerve structural organization ( ); GO:0021548 pons development ( ); GO:0021571 rhombomere 5 development ( ); GO:0021783 preganglionic parasympathetic nervous system development ( ); GO:0031371 ubiquitin conjugating enzyme complex ( ); GO:0004095 carnitine O-palmitoyltransferase activity ( ); GO:0016416 O-palmitoyltransferase activity ( ); GO:0015879 carnitine transport ( ); GO:0048486 parasympathetic nervous system development ( ); GO:0048532 anatomical structure arrangement ( ); GO:0048857 neural nucleus development ( ); GO:0021546 rhombomere development ( ); GO:0016406 carnitine O-acyltransferase activity ( ); GO:0015909 long-chain fatty acid transport ( ); GO:0021602 cranial nerve morphogenesis ( ); GO:0006282 regulation of DNA repair ( ); GO:0032365 intracellular lipid transport ( ); GO:0008045 motor axon guidance ( ); GO:0015908 fatty acid transport ( ); GO:0048483 autonomic nervous system development ( ); GO:0046320 regulation of fatty acid oxidation ( ); GO:0016409 palmitoyltransferase activity ( ); GO:0051181 cofactor transport ( ); GO:0021545 cranial nerve development ( ); GO:0008603 cAMP-dependent protein kinase regulator activity ( ); ----------------GO-------------- GO:0021570 rhombomere 4 development ( 0.00130659818284429 ); GO:0021754 facial nucleus development ( 0.00130659818284429 ); GO:0006853 carnitine shuttle ( 0.00195930615245954 ); GO:0021561 facial nerve development ( 0.00195930615245954 ); GO:0021569 rhombomere 3 development ( 0.00195930615245954 ); GO:0021604 cranial nerve structural organization ( 0.00195930615245954 ); GO:0021610 facial nerve morphogenesis ( 0.00195930615245954 ); GO:0021612 facial nerve structural organization ( 0.00195930615245954 ); GO:0021548 pons development ( 0.00261162033144524 ); GO:0021571 rhombomere 5 development ( 0.00261162033144524 ); GO:0021783 preganglionic parasympathetic nervous system development ( 0.00261162033144524 ); GO:0031371 ubiquitin conjugating enzyme complex ( 0.00261162033144524 ); GO:0004095 carnitine O-palmitoyltransferase activity ( 0.00261162033144524 ); GO:0016416 O-palmitoyltransferase activity ( 0.00261162033144524 ); GO:0015879 carnitine transport ( 0.00326354093759373 ); GO:0048486 parasympathetic nervous system development ( 0.00326354093759373 ); GO:0048532 anatomical structure arrangement ( 0.00326354093759373 ); GO:0048857 neural nucleus development ( 0.00326354093759373 ); GO:0021546 rhombomere development ( 0.00391506818859 ); GO:0016406 carnitine O-acyltransferase activity ( 0.00391506818859 ); GO:0015909 long-chain fatty acid transport ( 0.0045662023020081 ); GO:0021602 cranial nerve morphogenesis ( 0.0045662023020081 ); GO:0006282 regulation of DNA repair ( 0.00521694349531387 ); GO:0032365 intracellular lipid transport ( 0.00521694349531387 ); GO:0008045 motor axon guidance ( 0.00586729198586211 ); GO:0015908 fatty acid transport ( 0.00716681172756617 ); GO:0048483 autonomic nervous system development ( 0.00716681172756617 ); GO:0046320 regulation of fatty acid oxidation ( 0.00781598341288636 ); GO:0016409 palmitoyltransferase activity ( 0.00781598341288636 ); GO:0051181 cofactor transport ( 0.00846476326378098 ); GO:0021545 cranial nerve development ( 0.00911315149705938 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00976114832942221 ); ----------------KEGG-------------- hsa00071 Fatty acid metabolism ( 0.029656092555761 ); hsa05110 Vibrio cholerae infection ( 0.0372578041160895 ); hsa05120 Epithelial cell signaling in Helicobacter pylori infection ( 0.0429229711864871 ); hsa03320 PPAR signaling pathway ( 0.0435505310258184 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- PUM2_PAR-CLIP_(Hafner_2010) ( 0.0037195137450917 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.024676628913418 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.039554478088315 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2661 ========================= ----------------C2-------------- KEGG_CARDIAC_MUSCLE_CONTRACTION ( 0.000928488183233162 ); KEGG_LONG_TERM_POTENTIATION ( 0.000928488183233162 ); KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC ( 0.00100926326169553 ); KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM ( 0.00127118169881094 ); KEGG_DILATED_CARDIOMYOPATHY ( 0.001495069047304 ); KEGG_GNRH_SIGNALING_PATHWAY ( 0.0018821906625075 ); KEGG_CALCIUM_SIGNALING_PATHWAY ( 0.00575702905174348 ); BIOCARTA_CACAM_PATHWAY ( 0.00846476326378098 ); ----------------C3-------------- ( 0.00520208315109049 ); ----------------C4-------------- ( 0.00395722377023458 ); ----------------C5-------------- VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY ( 5.99618692375976e-05 ); CALCIUM_CHANNEL_ACTIVITY ( 0.000205786069682905 ); VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY ( 0.000825898641487694 ); VOLTAGE_GATED_CHANNEL_ACTIVITY ( 0.00100926326169553 ); CATION_CHANNEL_ACTIVITY ( 0.00256420291862378 ); GATED_CHANNEL_ACTIVITY ( 0.0027392725571125 ); METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00385201665041748 ); ION_CHANNEL_ACTIVITY ( 0.00395722377023458 ); SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY ( 0.0043359598900727 ); STEROID_DEHYDROGENASE_ACTIVITY__ACTING_ON_THE_CH_OH_GROUP_OF_DONORS__NAD_OR_NADP_AS_ACCEPTOR ( 0.00651724799090103 ); RESPONSE_TO_STEROID_HORMONE_STIMULUS ( 0.00716681172756617 ); STEROID_DEHYDROGENASE_ACTIVITY ( 0.00716681172756617 ); CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00801313874234222 ); SYNAPSE_PART ( 0.00846476326378098 ); N_METHYLTRANSFERASE_ACTIVITY ( 0.00846476326378098 ); CYTOSKELETAL_PART ( 0.00962544346942638 ); VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX ( 0.00976114832942221 ); ----------------GOSLIM-------------- GO:0006816 calcium ion transport ( ); GO:0005245 voltage-gated calcium channel activity ( ); GO:0015674 di-, tri-valent inorganic cation transport ( ); GO:0035238 vitamin A biosynthetic process ( ); GO:0042362 fat-soluble vitamin biosynthetic process ( ); GO:0042904 9-cis-retinoic acid biosynthetic process ( ); GO:0042905 9-cis-retinoic acid metabolic process ( ); GO:0008112 nicotinamide N-methyltransferase activity ( ); GO:0035254 glutamate receptor binding ( ); GO:0047035 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity ( ); GO:0005262 calcium channel activity ( ); GO:0030001 metal ion transport ( ); GO:0005516 calmodulin binding ( ); GO:0022843 voltage-gated cation channel activity ( ); GO:0042448 progesterone metabolic process ( ); GO:0006812 cation transport ( ); GO:0042572 retinol metabolic process ( ); GO:0043034 costamere ( ); GO:0015270 dihydropyridine-sensitive calcium channel activity ( ); GO:0005882 intermediate filament ( ); GO:0045111 intermediate filament cytoskeleton ( ); GO:0042573 retinoic acid metabolic process ( ); GO:0004022 alcohol dehydrogenase activity ( ); GO:0008209 androgen metabolic process ( ); GO:0004745 retinol dehydrogenase activity ( ); GO:0005244 voltage-gated ion channel activity ( ); GO:0022832 voltage-gated channel activity ( ); GO:0046928 regulation of neurotransmitter secretion ( ); GO:0045214 sarcomere organization ( ); GO:0016854 racemase and epimerase activity ( ); GO:0001523 retinoid metabolic process ( ); GO:0016101 diterpenoid metabolic process ( ); GO:0014069 postsynaptic density ( ); GO:0006721 terpenoid metabolic process ( ); GO:0048168 regulation of neuronal synaptic plasticity ( ); GO:0006811 ion transport ( ); ----------------GO-------------- GO:0006816 calcium ion transport ( 8.31724004888171e-05 ); GO:0005245 voltage-gated calcium channel activity ( 0.000107927496752941 ); GO:0015674 di-, tri-valent inorganic cation transport ( 0.000153474531772805 ); GO:0035238 vitamin A biosynthetic process ( 0.000653496204695458 ); GO:0042362 fat-soluble vitamin biosynthetic process ( 0.000653496204695458 ); GO:0042904 9-cis-retinoic acid biosynthetic process ( 0.000653496204695458 ); GO:0042905 9-cis-retinoic acid metabolic process ( 0.000653496204695458 ); GO:0008112 nicotinamide N-methyltransferase activity ( 0.000653496204695458 ); GO:0035254 glutamate receptor binding ( 0.000653496204695458 ); GO:0047035 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity ( 0.000653496204695458 ); GO:0005262 calcium channel activity ( 0.000981974023087663 ); GO:0030001 metal ion transport ( 0.00269060497428652 ); GO:0005516 calmodulin binding ( 0.00296585104998705 ); GO:0022843 voltage-gated cation channel activity ( 0.00334615098336977 ); GO:0042448 progesterone metabolic process ( 0.00391506818859 ); GO:0006812 cation transport ( 0.00413176632780688 ); GO:0042572 retinol metabolic process ( 0.0045662023020081 ); GO:0043034 costamere ( 0.0045662023020081 ); GO:0015270 dihydropyridine-sensitive calcium channel activity ( 0.0045662023020081 ); GO:0005882 intermediate filament ( 0.00473094508395179 ); GO:0045111 intermediate filament cytoskeleton ( 0.0047886902389396 ); GO:0042573 retinoic acid metabolic process ( 0.00521694349531387 ); GO:0004022 alcohol dehydrogenase activity ( 0.00521694349531387 ); GO:0008209 androgen metabolic process ( 0.00586729198586211 ); GO:0004745 retinol dehydrogenase activity ( 0.00586729198586211 ); GO:0005244 voltage-gated ion channel activity ( 0.0062067210550971 ); GO:0022832 voltage-gated channel activity ( 0.0062067210550971 ); GO:0046928 regulation of neurotransmitter secretion ( 0.00716681172756617 ); GO:0045214 sarcomere organization ( 0.00781598341288636 ); GO:0016854 racemase and epimerase activity ( 0.00781598341288636 ); GO:0001523 retinoid metabolic process ( 0.00846476326378098 ); GO:0016101 diterpenoid metabolic process ( 0.00846476326378098 ); GO:0014069 postsynaptic density ( 0.00846476326378098 ); GO:0006721 terpenoid metabolic process ( 0.00976114832942221 ); GO:0048168 regulation of neuronal synaptic plasticity ( 0.00976114832942221 ); GO:0006811 ion transport ( 0.00998227532939844 ); ----------------KEGG-------------- hsa04720 Long-term potentiation ( 0.000955048859106439 ); hsa04912 GnRH signaling pathway ( 0.00184522655779007 ); hsa04020 Calcium signaling pathway ( 0.00582030668275143 ); hsa04010 MAPK signaling pathway ( 0.0125169504785284 ); hsa00760 Nicotinate and nicotinamide metabolism ( 0.015575542481185 ); hsa04740 Olfactory transduction ( 0.0243387348238841 ); hsa04930 Type II diabetes mellitus ( 0.0264723915777242 ); hsa00830 Retinol metabolism ( 0.0359946818262533 ); hsa05214 Glioma ( 0.0410380104010674 ); ----------------CARTA-------------- ( 0.00521694349531387 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2894 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$SREBP_Q3 ( 0.00614151715774623 ); V$E2F1_Q3_01 ( 0.00640424952090116 ); V$HOXA3_01 ( 0.00716681172756617 ); ----------------C4-------------- module_231 ( 0.00586729198586211 ); module_402 ( 0.00781598341288636 ); ----------------C5-------------- CARBOXYPEPTIDASE_ACTIVITY ( 0.00781598341288636 ); METALLOEXOPEPTIDASE_ACTIVITY ( 0.00846476326378098 ); ----------------GOSLIM-------------- GO:0033327 Leydig cell differentiation ( ); GO:0017121 phospholipid scrambling ( ); GO:0017128 phospholipid scramblase activity ( ); GO:0008233 peptidase activity ( ); GO:0030238 male sex determination ( ); GO:0050810 regulation of steroid biosynthetic process ( ); GO:0001892 embryonic placenta development ( ); GO:0007009 plasma membrane organization ( ); ----------------GO-------------- GO:0033327 Leydig cell differentiation ( 0.00130659818284429 ); GO:0017121 phospholipid scrambling ( 0.00261162033144524 ); GO:0017128 phospholipid scramblase activity ( 0.00261162033144524 ); GO:0008233 peptidase activity ( 0.00440606965100215 ); GO:0030238 male sex determination ( 0.00586729198586211 ); GO:0050810 regulation of steroid biosynthetic process ( 0.00846476326378098 ); GO:0001892 embryonic placenta development ( 0.00911315149705938 ); GO:0007009 plasma membrane organization ( 0.00911315149705938 ); ----------------KEGG-------------- ( 0.0366264340638022 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2899 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$CEBP_Q3 ( 0.00667207914852313 ); V$HNF1_Q6 ( 0.00673983016834846 ); ----------------C4-------------- ( ); ----------------C5-------------- ANATOMICAL_STRUCTURE_DEVELOPMENT ( 0.00313882032494494 ); POSITIVE_REGULATION_OF_ANGIOGENESIS ( 0.00586729198586211 ); POSITIVE_REGULATION_OF_CELL_MIGRATION ( 0.00651724799090103 ); REGULATION_OF_LIPID_METABOLIC_PROCESS ( 0.00781598341288636 ); NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY ( 0.00911315149705938 ); POSITIVE_REGULATION_OF_METABOLIC_PROCESS ( 0.00930795850196337 ); REGULATION_OF_CATABOLIC_PROCESS ( 0.00976114832942221 ); ----------------GOSLIM-------------- GO:0010519 negative regulation of phospholipase activity ( ); GO:0004996 thyroid-stimulating hormone receptor activity ( ); GO:0055090 acylglycerol homeostasis ( ); GO:0050996 positive regulation of lipid catabolic process ( ); GO:0051005 negative regulation of lipoprotein lipase activity ( ); GO:0055091 phospholipid homeostasis ( ); GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome ( ); GO:0060192 negative regulation of lipase activity ( ); GO:0016042 lipid catabolic process ( ); GO:0000380 alternative nuclear mRNA splicing, via spliceosome ( ); GO:0048024 regulation of nuclear mRNA splicing, via spliceosome ( ); GO:0048844 artery morphogenesis ( ); GO:0050994 regulation of lipid catabolic process ( ); GO:0043484 regulation of RNA splicing ( ); GO:0004622 lysophospholipase activity ( ); GO:0004859 phospholipase inhibitor activity ( ); GO:0016500 protein-hormone receptor activity ( ); GO:0050684 regulation of mRNA processing ( ); GO:0051004 regulation of lipoprotein lipase activity ( ); GO:0055102 lipase inhibitor activity ( ); ----------------GO-------------- GO:0010519 negative regulation of phospholipase activity ( 0.000653496204695458 ); GO:0004996 thyroid-stimulating hormone receptor activity ( 0.00130659818284429 ); GO:0055090 acylglycerol homeostasis ( 0.00195930615245954 ); GO:0050996 positive regulation of lipid catabolic process ( 0.00261162033144524 ); GO:0051005 negative regulation of lipoprotein lipase activity ( 0.00261162033144524 ); GO:0055091 phospholipid homeostasis ( 0.00261162033144524 ); GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome ( 0.00326354093759373 ); GO:0060192 negative regulation of lipase activity ( 0.00326354093759373 ); GO:0016042 lipid catabolic process ( 0.00444716055779937 ); GO:0000380 alternative nuclear mRNA splicing, via spliceosome ( 0.0045662023020081 ); GO:0048024 regulation of nuclear mRNA splicing, via spliceosome ( 0.0045662023020081 ); GO:0048844 artery morphogenesis ( 0.00586729198586211 ); GO:0050994 regulation of lipid catabolic process ( 0.00651724799090103 ); GO:0043484 regulation of RNA splicing ( 0.00716681172756617 ); GO:0004622 lysophospholipase activity ( 0.00716681172756617 ); GO:0004859 phospholipase inhibitor activity ( 0.00716681172756617 ); GO:0016500 protein-hormone receptor activity ( 0.00716681172756617 ); GO:0050684 regulation of mRNA processing ( 0.00781598341288636 ); GO:0051004 regulation of lipoprotein lipase activity ( 0.00846476326378098 ); GO:0055102 lipase inhibitor activity ( 0.00911315149705938 ); ----------------KEGG-------------- ( 0.0187921279796281 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0160440099353936 ); ----------------ARE-------------- ( ); ============================ group2950 ========================= ----------------C2-------------- REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION ( 0.00586729198586211 ); KEGG_FOLATE_BIOSYNTHESIS ( 0.00716681172756617 ); REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX ( 0.00716681172756617 ); REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS ( 0.00716681172756617 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_GMPS ( 0.00045564637751238 ); MORF_PTPN11 ( 0.00170090448228941 ); module_8 ( 0.00204348482614374 ); module_52 ( 0.00214612386868374 ); module_18 ( 0.00248960135016252 ); GCM_MYST2 ( 0.00349436858936858 ); module_31 ( 0.0045662023020081 ); module_376 ( 0.0045662023020081 ); module_140 ( 0.00521694349531387 ); module_538 ( 0.00521694349531387 ); module_450 ( 0.00586729198586211 ); module_21 ( 0.00651724799090103 ); module_56 ( 0.00781598341288636 ); ----------------C5-------------- ( 0.000126994864046695 ); ----------------GOSLIM-------------- GO:0015790 UDP-xylose transport ( ); GO:0003874 6-pyruvoyltetrahydropterin synthase activity ( ); GO:0003921 GMP synthase activity ( ); GO:0003922 GMP synthase (glutamine-hydrolyzing) activity ( ); GO:0005464 UDP-xylose transmembrane transporter activity ( ); GO:0015788 UDP-N-acetylglucosamine transport ( ); GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity ( ); GO:0016838 carbon-oxygen lyase activity, acting on phosphates ( ); GO:0006177 GMP biosynthetic process ( ); GO:0046037 GMP metabolic process ( ); GO:0006725 cellular aromatic compound metabolic process ( ); GO:0015781 pyrimidine nucleotide-sugar transport ( ); GO:0005664 nuclear origin of replication recognition complex ( ); GO:0015780 nucleotide-sugar transport ( ); GO:0000808 origin recognition complex ( ); GO:0015165 pyrimidine nucleotide sugar transmembrane transporter activity ( ); GO:0006729 tetrahydrobiopterin biosynthetic process ( ); GO:0009113 purine base biosynthetic process ( ); GO:0046146 tetrahydrobiopterin metabolic process ( ); GO:0005338 nucleotide-sugar transmembrane transporter activity ( ); GO:0006558 L-phenylalanine metabolic process ( ); GO:0006559 L-phenylalanine catabolic process ( ); GO:0046112 nucleobase biosynthetic process ( ); GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor ( ); GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process ( ); GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process ( ); GO:0042559 pteridine and derivative biosynthetic process ( ); GO:0006520 amino acid metabolic process ( ); GO:0009074 aromatic amino acid family catabolic process ( ); GO:0019438 aromatic compound biosynthetic process ( ); GO:0006144 purine base metabolic process ( ); GO:0042558 pteridine and derivative metabolic process ( ); ----------------GO-------------- GO:0015790 UDP-xylose transport ( 0.000653496204695458 ); GO:0003874 6-pyruvoyltetrahydropterin synthase activity ( 0.000653496204695458 ); GO:0003921 GMP synthase activity ( 0.000653496204695458 ); GO:0003922 GMP synthase (glutamine-hydrolyzing) activity ( 0.000653496204695458 ); GO:0005464 UDP-xylose transmembrane transporter activity ( 0.000653496204695458 ); GO:0015788 UDP-N-acetylglucosamine transport ( 0.00130659818284429 ); GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity ( 0.00130659818284429 ); GO:0016838 carbon-oxygen lyase activity, acting on phosphates ( 0.00130659818284429 ); GO:0006177 GMP biosynthetic process ( 0.00195930615245954 ); GO:0046037 GMP metabolic process ( 0.00195930615245954 ); GO:0006725 cellular aromatic compound metabolic process ( 0.00203356928288962 ); GO:0015781 pyrimidine nucleotide-sugar transport ( 0.00261162033144524 ); GO:0005664 nuclear origin of replication recognition complex ( 0.00261162033144524 ); GO:0015780 nucleotide-sugar transport ( 0.00326354093759373 ); GO:0000808 origin recognition complex ( 0.00326354093759373 ); GO:0015165 pyrimidine nucleotide sugar transmembrane transporter activity ( 0.00326354093759373 ); GO:0006729 tetrahydrobiopterin biosynthetic process ( 0.00391506818859 ); GO:0009113 purine base biosynthetic process ( 0.0045662023020081 ); GO:0046146 tetrahydrobiopterin metabolic process ( 0.0045662023020081 ); GO:0005338 nucleotide-sugar transmembrane transporter activity ( 0.0045662023020081 ); GO:0006558 L-phenylalanine metabolic process ( 0.00521694349531387 ); GO:0006559 L-phenylalanine catabolic process ( 0.00521694349531387 ); GO:0046112 nucleobase biosynthetic process ( 0.00651724799090103 ); GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor ( 0.00651724799090103 ); GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process ( 0.00781598341288636 ); GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process ( 0.00781598341288636 ); GO:0042559 pteridine and derivative biosynthetic process ( 0.00781598341288636 ); GO:0006520 amino acid metabolic process ( 0.00816085634465429 ); GO:0009074 aromatic amino acid family catabolic process ( 0.00846476326378098 ); GO:0019438 aromatic compound biosynthetic process ( 0.00846476326378098 ); GO:0006144 purine base metabolic process ( 0.00911315149705938 ); GO:0042558 pteridine and derivative metabolic process ( 0.00976114832942221 ); ----------------KEGG-------------- hsa00251 Glutamate metabolism ( 0.015575542481185 ); hsa00790 Folate biosynthesis ( 0.0213584081427761 ); hsa00983 Drug metabolism - other enzymes ( 0.0283837672291989 ); ----------------CARTA-------------- malpathway ( 0.0149310585235009 ); longevitypathway ( 0.0175066597767723 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2970 ========================= ----------------C2-------------- ( 0.00651724799090103 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- POSITIVE_REGULATION_OF_CYTOKINE_SECRETION ( 0.00586729198586211 ); INTERLEUKIN_1_SECRETION ( 0.00651724799090103 ); POSITIVE_REGULATION_OF_PROTEIN_SECRETION ( 0.00716681172756617 ); AXON ( 0.00781598341288636 ); REGULATION_OF_CYTOKINE_SECRETION ( 0.00976114832942221 ); ----------------GOSLIM-------------- GO:0033693 neurofilament bundle assembly ( ); GO:0008090 retrograde axon cargo transport ( ); GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity ( ); GO:0032090 Pyrin domain binding ( ); GO:0019896 axon transport of mitochondrion ( ); GO:0033596 TSC1-TSC2 complex ( ); GO:0004069 aspartate transaminase activity ( ); GO:0016882 cyclo-ligase activity ( ); GO:0008089 anterograde axon cargo transport ( ); GO:0045110 intermediate filament bundle assembly ( ); GO:0019642 anaerobic glycolysis ( ); GO:0060052 neurofilament cytoskeleton organization ( ); GO:0005883 neurofilament ( ); GO:0004459 L-lactate dehydrogenase activity ( ); GO:0060053 neurofilament cytoskeleton ( ); GO:0004457 lactate dehydrogenase activity ( ); GO:0045109 intermediate filament organization ( ); GO:0009396 folic acid and derivative biosynthetic process ( ); GO:0050718 positive regulation of interleukin-1 beta secretion ( ); GO:0008088 axon cargo transport ( ); GO:0050706 regulation of interleukin-1 beta secretion ( ); GO:0050716 positive regulation of interleukin-1 secretion ( ); GO:0050704 regulation of interleukin-1 secretion ( ); GO:0050702 interleukin-1 beta secretion ( ); GO:0050701 interleukin-1 secretion ( ); GO:0006760 folic acid and derivative metabolic process ( ); GO:0045104 intermediate filament cytoskeleton organization ( ); ----------------GO-------------- GO:0033693 neurofilament bundle assembly ( 0.000653496204695458 ); GO:0008090 retrograde axon cargo transport ( 0.00130659818284429 ); GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity ( 0.00130659818284429 ); GO:0032090 Pyrin domain binding ( 0.00130659818284429 ); GO:0019896 axon transport of mitochondrion ( 0.00195930615245954 ); GO:0033596 TSC1-TSC2 complex ( 0.00195930615245954 ); GO:0004069 aspartate transaminase activity ( 0.00195930615245954 ); GO:0016882 cyclo-ligase activity ( 0.00195930615245954 ); GO:0008089 anterograde axon cargo transport ( 0.00261162033144524 ); GO:0045110 intermediate filament bundle assembly ( 0.00261162033144524 ); GO:0019642 anaerobic glycolysis ( 0.00326354093759373 ); GO:0060052 neurofilament cytoskeleton organization ( 0.00326354093759373 ); GO:0005883 neurofilament ( 0.00326354093759373 ); GO:0004459 L-lactate dehydrogenase activity ( 0.00326354093759373 ); GO:0060053 neurofilament cytoskeleton ( 0.00391506818859 ); GO:0004457 lactate dehydrogenase activity ( 0.00391506818859 ); GO:0045109 intermediate filament organization ( 0.00521694349531387 ); GO:0009396 folic acid and derivative biosynthetic process ( 0.00586729198586211 ); GO:0050718 positive regulation of interleukin-1 beta secretion ( 0.00651724799090103 ); GO:0008088 axon cargo transport ( 0.00716681172756617 ); GO:0050706 regulation of interleukin-1 beta secretion ( 0.00716681172756617 ); GO:0050716 positive regulation of interleukin-1 secretion ( 0.00716681172756617 ); GO:0050704 regulation of interleukin-1 secretion ( 0.00781598341288636 ); GO:0050702 interleukin-1 beta secretion ( 0.00846476326378098 ); GO:0050701 interleukin-1 secretion ( 0.00911315149705938 ); GO:0006760 folic acid and derivative metabolic process ( 0.00976114832942221 ); GO:0045104 intermediate filament cytoskeleton organization ( 0.00976114832942221 ); ----------------KEGG-------------- hsa00272 Cysteine metabolism ( 0.00846476326378098 ); hsa00640 Propanoate metabolism ( 0.0226392235398694 ); hsa00620 Pyruvate metabolism ( 0.0271099021010718 ); hsa00562 Inositol phosphate metabolism ( 0.0309268797870798 ); hsa05014 Amyotrophic lateral sclerosis (ALS) ( 0.035362547191385 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.0397794667100285 ); hsa04070 Phosphatidylinositol signaling system ( 0.0485573524840712 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2989 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$ETF_Q6 ( 0.00112205270379444 ); V$AREB6_01 ( 0.0070139973893108 ); V$AML_Q6 ( 0.0070139973893108 ); V$EFC_Q6 ( 0.00772142596931898 ); V$IK1_01 ( 0.00779388792869068 ); TGCACGA,MIR-517A,MIR-517C ( 0.00911315149705938 ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00781598341288636 ); ----------------GOSLIM-------------- GO:0001829 trophectodermal cell differentiation ( ); GO:0001825 blastocyst formation ( ); GO:0001892 embryonic placenta development ( ); ----------------GO-------------- GO:0001829 trophectodermal cell differentiation ( 0.00716681172756617 ); GO:0001825 blastocyst formation ( 0.00846476326378098 ); GO:0001892 embryonic placenta development ( 0.00911315149705938 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2996 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0045163 clustering of voltage-gated potassium channels ( ); GO:0005250 A-type (transient outward) potassium channel activity ( ); GO:0008140 cAMP response element binding protein binding ( ); GO:0015271 outward rectifier potassium channel activity ( ); GO:0046923 ER retention sequence binding ( ); GO:0045161 neuronal ion channel clustering ( ); GO:0005513 detection of calcium ion ( ); GO:0043020 NADPH oxidase complex ( ); GO:0042554 superoxide release ( ); GO:0042551 neuron maturation ( ); GO:0045730 respiratory burst ( ); ----------------GO-------------- GO:0045163 clustering of voltage-gated potassium channels ( 0.000653496204695458 ); GO:0005250 A-type (transient outward) potassium channel activity ( 0.00130659818284429 ); GO:0008140 cAMP response element binding protein binding ( 0.00195930615245954 ); GO:0015271 outward rectifier potassium channel activity ( 0.00195930615245954 ); GO:0046923 ER retention sequence binding ( 0.00261162033144524 ); GO:0045161 neuronal ion channel clustering ( 0.00391506818859 ); GO:0005513 detection of calcium ion ( 0.00586729198586211 ); GO:0043020 NADPH oxidase complex ( 0.00586729198586211 ); GO:0042554 superoxide release ( 0.00781598341288636 ); GO:0042551 neuron maturation ( 0.00976114832942221 ); GO:0045730 respiratory burst ( 0.00976114832942221 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3064 ========================= ----------------C2-------------- ( ); ----------------C3-------------- AGGTGCA,MIR-500 ( 0.00121044735520581 ); CAGTATT,MIR-200B,MIR-200C,MIR-429 ( 0.00178065231050792 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0010389 regulation of G2/M transition of mitotic cell cycle ( ); GO:0004862 cAMP-dependent protein kinase inhibitor activity ( ); GO:0043565 sequence-specific DNA binding ( ); GO:0030299 cholesterol absorption ( ); GO:0008158 hedgehog receptor activity ( ); GO:0044241 lipid digestion ( ); GO:0042308 negative regulation of protein import into nucleus ( ); GO:0050892 intestinal absorption ( ); GO:0000086 G2/M transition of mitotic cell cycle ( ); GO:0046823 negative regulation of nucleocytoplasmic transport ( ); ----------------GO-------------- GO:0010389 regulation of G2/M transition of mitotic cell cycle ( 0.00130659818284429 ); GO:0004862 cAMP-dependent protein kinase inhibitor activity ( 0.00261162033144524 ); GO:0043565 sequence-specific DNA binding ( 0.00397675998119679 ); GO:0030299 cholesterol absorption ( 0.00586729198586211 ); GO:0008158 hedgehog receptor activity ( 0.00586729198586211 ); GO:0044241 lipid digestion ( 0.00716681172756617 ); GO:0042308 negative regulation of protein import into nucleus ( 0.00846476326378098 ); GO:0050892 intestinal absorption ( 0.00846476326378098 ); GO:0000086 G2/M transition of mitotic cell cycle ( 0.00976114832942221 ); GO:0046823 negative regulation of nucleocytoplasmic transport ( 0.00976114832942221 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3091 ========================= ----------------C2-------------- ( 0.00846476326378098 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00911315149705938 ); ----------------GOSLIM-------------- GO:0043490 malate-aspartate shuttle ( ); GO:0015810 aspartate transport ( ); GO:0015183 L-aspartate transmembrane transporter activity ( ); GO:0004176 ATP-dependent peptidase activity ( ); GO:0005313 L-glutamate transmembrane transporter activity ( ); GO:0015172 acidic amino acid transmembrane transporter activity ( ); GO:0015800 acidic amino acid transport ( ); GO:0015813 L-glutamate transport ( ); ----------------GO-------------- GO:0043490 malate-aspartate shuttle ( 0.00130659818284429 ); GO:0015810 aspartate transport ( 0.00195930615245954 ); GO:0015183 L-aspartate transmembrane transporter activity ( 0.00195930615245954 ); GO:0004176 ATP-dependent peptidase activity ( 0.0045662023020081 ); GO:0005313 L-glutamate transmembrane transporter activity ( 0.00716681172756617 ); GO:0015172 acidic amino acid transmembrane transporter activity ( 0.00716681172756617 ); GO:0015800 acidic amino acid transport ( 0.00911315149705938 ); GO:0015813 L-glutamate transport ( 0.00911315149705938 ); ----------------KEGG-------------- ( 0.0479328256263228 ); ----------------CARTA-------------- pcafpathway ( 0.00651724799090103 ); fibrinolysispathway ( 0.0117027925863891 ); igf1pathway ( 0.0149310585235009 ); pdgfpathway ( 0.0290201222609904 ); fcer1pathway ( 0.0315616971497789 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00582177547155401 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0396036649494864 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3217 ========================= ----------------C2-------------- BIOCARTA_P38MAPK_PATHWAY ( 0.000288163965803141 ); KEGG_LEISHMANIA_INFECTION ( 0.000850997223805812 ); BIOCARTA_MAPK_PATHWAY ( 0.00139696659341563 ); REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION ( 0.00651724799090103 ); BIOCARTA_ERYTH_PATHWAY ( 0.00976114832942221 ); REACTOME_SIGNALING_BY_TGF_BETA ( 0.00976114832942221 ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_STAT6 ( 0.00106493231044165 ); module_152 ( 0.00269498785684813 ); module_195 ( 0.00339521833048076 ); module_356 ( 0.00354445071406457 ); ----------------C5-------------- MUSCLE_DEVELOPMENT ( 0.00159638534466046 ); POSITIVE_REGULATION_OF_TRANSCRIPTION__DNA_DEPENDENT ( 0.00247874125144887 ); POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS ( 0.00256420291862378 ); POSITIVE_REGULATION_OF_TRANSCRIPTION ( 0.00354445071406457 ); POSITIVE_REGULATION_OF_NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS ( 0.00401032903370021 ); EPITHELIAL_TO_MESENCHYMAL_TRANSITION ( 0.00586729198586211 ); POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS ( 0.00651724799090103 ); PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE ( 0.00781598341288636 ); POSITIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.00876406559977926 ); REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY ( 0.00911315149705938 ); POSITIVE_REGULATION_OF_METABOLIC_PROCESS ( 0.00930795850196337 ); ----------------GOSLIM-------------- GO:0009814 defense response, incompatible interaction ( ); GO:0009817 defense response to fungus, incompatible interaction ( ); GO:0010799 regulation of peptidyl-threonine phosphorylation ( ); GO:0010800 positive regulation of peptidyl-threonine phosphorylation ( ); GO:0048290 isotype switching to IgA isotypes ( ); GO:0048296 regulation of isotype switching to IgA isotypes ( ); GO:0048298 positive regulation of isotype switching to IgA isotypes ( ); GO:0051280 negative regulation of release of sequestered calcium ion into cytosol ( ); GO:0033961 cis-stilbene-oxide hydrolase activity ( ); GO:0002513 tolerance induction to self antigen ( ); GO:0010523 negative regulation of calcium ion transport into cytosol ( ); GO:0010718 positive regulation of epithelial to mesenchymal transition ( ); GO:0010761 fibroblast cell migration ( ); GO:0010762 regulation of fibroblast cell migration ( ); GO:0010763 positive regulation of fibroblast cell migration ( ); GO:0010770 positive regulation of cell morphogenesis involved in differentiation ( ); GO:0019049 evasion of host defenses by virus ( ); GO:0032620 interleukin-17 production ( ); GO:0032660 regulation of interleukin-17 production ( ); GO:0032740 positive regulation of interleukin-17 production ( ); GO:0043551 regulation of phosphoinositide 3-kinase activity ( ); GO:0043552 positive regulation of phosphoinositide 3-kinase activity ( ); GO:0043932 ossification involved in bone remodeling ( ); GO:0044413 avoidance of host defenses ( ); GO:0044415 evasion or tolerance of host defenses ( ); GO:0050765 negative regulation of phagocytosis ( ); GO:0051832 avoidance of defenses of other organism during symbiotic interaction ( ); GO:0051834 evasion or tolerance of defenses of other organism during symbiotic interaction ( ); GO:0009145 purine nucleoside triphosphate biosynthetic process ( ); GO:0009206 purine ribonucleoside triphosphate biosynthetic process ( ); GO:0009142 nucleoside triphosphate biosynthetic process ( ); GO:0009201 ribonucleoside triphosphate biosynthetic process ( ); GO:0001667 ameboidal cell migration ( ); GO:0002248 connective tissue replacement during inflammatory response ( ); GO:0010717 regulation of epithelial to mesenchymal transition ( ); GO:0031536 positive regulation of exit from mitosis ( ); GO:0035306 positive regulation of dephosphorylation ( ); GO:0035307 positive regulation of protein amino acid dephosphorylation ( ); GO:0045066 regulatory T cell differentiation ( ); GO:0051279 regulation of release of sequestered calcium ion into cytosol ( ); GO:0051897 positive regulation of protein kinase B signaling cascade ( ); GO:0052173 response to defenses of other organism during symbiotic interaction ( ); GO:0052200 response to host defenses ( ); GO:0009205 purine ribonucleoside triphosphate metabolic process ( ); GO:0009144 purine nucleoside triphosphate metabolic process ( ); GO:0009199 ribonucleoside triphosphate metabolic process ( ); GO:0009141 nucleoside triphosphate metabolic process ( ); GO:0009152 purine ribonucleotide biosynthetic process ( ); GO:0006164 purine nucleotide biosynthetic process ( ); GO:0002246 healing during inflammatory response ( ); GO:0007435 salivary gland morphogenesis ( ); GO:0010714 positive regulation of collagen metabolic process ( ); GO:0032967 positive regulation of collagen biosynthetic process ( ); GO:0033160 positive regulation of protein import into nucleus, translocation ( ); GO:0035304 regulation of protein amino acid dephosphorylation ( ); GO:0060390 regulation of SMAD protein nuclear translocation ( ); GO:0060391 positive regulation of SMAD protein nuclear translocation ( ); GO:0004301 epoxide hydrolase activity ( ); GO:0009260 ribonucleotide biosynthetic process ( ); GO:0009150 purine ribonucleotide metabolic process ( ); GO:0009259 ribonucleotide metabolic process ( ); GO:0002507 tolerance induction ( ); GO:0032965 regulation of collagen biosynthetic process ( ); GO:0033158 regulation of protein import into nucleus, translocation ( ); GO:0045830 positive regulation of isotype switching ( ); GO:0045911 positive regulation of DNA recombination ( ); GO:0016803 ether hydrolase activity ( ); GO:0006163 purine nucleotide metabolic process ( ); GO:0007406 negative regulation of neuroblast proliferation ( ); GO:0007431 salivary gland development ( ); GO:0010712 regulation of collagen metabolic process ( ); GO:0022612 gland morphogenesis ( ); GO:0033135 regulation of peptidyl-serine phosphorylation ( ); GO:0033138 positive regulation of peptidyl-serine phosphorylation ( ); GO:0043011 myeloid dendritic cell differentiation ( ); GO:0043536 positive regulation of blood vessel endothelial cell migration ( ); GO:0043550 regulation of lipid kinase activity ( ); GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity ( ); GO:0005114 type II transforming growth factor beta receptor binding ( ); GO:0008354 germ cell migration ( ); GO:0018107 peptidyl-threonine phosphorylation ( ); GO:0035303 regulation of dephosphorylation ( ); GO:0044253 positive regulation of multicellular organismal metabolic process ( ); GO:0051896 regulation of protein kinase B signaling cascade ( ); GO:0051926 negative regulation of calcium ion transport ( ); GO:0001773 myeloid dendritic cell activation ( ); GO:0010595 positive regulation of endothelial cell migration ( ); GO:0043537 negative regulation of blood vessel endothelial cell migration ( ); GO:0016801 hydrolase activity, acting on ether bonds ( ); GO:0019048 virus-host interaction ( ); GO:0032964 collagen biosynthetic process ( ); GO:0044246 regulation of multicellular organismal metabolic process ( ); GO:0045191 regulation of isotype switching ( ); GO:0051209 release of sequestered calcium ion into cytosol ( ); GO:0051282 regulation of sequestering of calcium ion ( ); GO:0051283 negative regulation of sequestering of calcium ion ( ); GO:0005796 Golgi lumen ( ); GO:0006631 fatty acid metabolic process ( ); GO:0006183 GTP biosynthetic process ( ); GO:0006228 UTP biosynthetic process ( ); GO:0010522 regulation of calcium ion transport into cytosol ( ); GO:0018210 peptidyl-threonine modification ( ); GO:0030279 negative regulation of ossification ( ); GO:0035272 exocrine system development ( ); GO:0043271 negative regulation of ion transport ( ); GO:0046051 UTP metabolic process ( ); GO:0004550 nucleoside diphosphate kinase activity ( ); GO:0006241 CTP biosynthetic process ( ); GO:0007096 regulation of exit from mitosis ( ); GO:0007184 SMAD protein nuclear translocation ( ); GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process ( ); GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process ( ); GO:0043491 protein kinase B signaling cascade ( ); GO:0045806 negative regulation of endocytosis ( ); GO:0045930 negative regulation of mitotic cell cycle ( ); GO:0046036 CTP metabolic process ( ); GO:0046039 GTP metabolic process ( ); GO:0050764 regulation of phagocytosis ( ); GO:0009147 pyrimidine nucleoside triphosphate metabolic process ( ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( ); GO:0031575 G1/S transition checkpoint ( ); GO:0043535 regulation of blood vessel endothelial cell migration ( ); GO:0050832 defense response to fungus ( ); GO:0051208 sequestering of calcium ion ( ); GO:0006897 endocytosis ( ); GO:0010324 membrane invagination ( ); GO:0001933 negative regulation of protein amino acid phosphorylation ( ); GO:0010458 exit from mitosis ( ); GO:0010596 negative regulation of endothelial cell migration ( ); GO:0046851 negative regulation of bone remodeling ( ); GO:0050777 negative regulation of immune response ( ); GO:0002637 regulation of immunoglobulin production ( ); GO:0050680 negative regulation of epithelial cell proliferation ( ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( ); GO:0030501 positive regulation of bone mineralization ( ); GO:0032845 negative regulation of homeostatic process ( ); GO:0034104 negative regulation of tissue remodeling ( ); GO:0043029 T cell homeostasis ( ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( ); ----------------GO-------------- GO:0009814 defense response, incompatible interaction ( 0.000653496204695458 ); GO:0009817 defense response to fungus, incompatible interaction ( 0.000653496204695458 ); GO:0010799 regulation of peptidyl-threonine phosphorylation ( 0.000653496204695458 ); GO:0010800 positive regulation of peptidyl-threonine phosphorylation ( 0.000653496204695458 ); GO:0048290 isotype switching to IgA isotypes ( 0.000653496204695458 ); GO:0048296 regulation of isotype switching to IgA isotypes ( 0.000653496204695458 ); GO:0048298 positive regulation of isotype switching to IgA isotypes ( 0.000653496204695458 ); GO:0051280 negative regulation of release of sequestered calcium ion into cytosol ( 0.000653496204695458 ); GO:0033961 cis-stilbene-oxide hydrolase activity ( 0.000653496204695458 ); GO:0002513 tolerance induction to self antigen ( 0.00130659818284429 ); GO:0010523 negative regulation of calcium ion transport into cytosol ( 0.00130659818284429 ); GO:0010718 positive regulation of epithelial to mesenchymal transition ( 0.00130659818284429 ); GO:0010761 fibroblast cell migration ( 0.00130659818284429 ); GO:0010762 regulation of fibroblast cell migration ( 0.00130659818284429 ); GO:0010763 positive regulation of fibroblast cell migration ( 0.00130659818284429 ); GO:0010770 positive regulation of cell morphogenesis involved in differentiation ( 0.00130659818284429 ); GO:0019049 evasion of host defenses by virus ( 0.00130659818284429 ); GO:0032620 interleukin-17 production ( 0.00130659818284429 ); GO:0032660 regulation of interleukin-17 production ( 0.00130659818284429 ); GO:0032740 positive regulation of interleukin-17 production ( 0.00130659818284429 ); GO:0043551 regulation of phosphoinositide 3-kinase activity ( 0.00130659818284429 ); GO:0043552 positive regulation of phosphoinositide 3-kinase activity ( 0.00130659818284429 ); GO:0043932 ossification involved in bone remodeling ( 0.00130659818284429 ); GO:0044413 avoidance of host defenses ( 0.00130659818284429 ); GO:0044415 evasion or tolerance of host defenses ( 0.00130659818284429 ); GO:0050765 negative regulation of phagocytosis ( 0.00130659818284429 ); GO:0051832 avoidance of defenses of other organism during symbiotic interaction ( 0.00130659818284429 ); GO:0051834 evasion or tolerance of defenses of other organism during symbiotic interaction ( 0.00130659818284429 ); GO:0009145 purine nucleoside triphosphate biosynthetic process ( 0.00170090448228941 ); GO:0009206 purine ribonucleoside triphosphate biosynthetic process ( 0.00170090448228941 ); GO:0009142 nucleoside triphosphate biosynthetic process ( 0.00173645403896178 ); GO:0009201 ribonucleoside triphosphate biosynthetic process ( 0.00173645403896178 ); GO:0001667 ameboidal cell migration ( 0.00195930615245954 ); GO:0002248 connective tissue replacement during inflammatory response ( 0.00195930615245954 ); GO:0010717 regulation of epithelial to mesenchymal transition ( 0.00195930615245954 ); GO:0031536 positive regulation of exit from mitosis ( 0.00195930615245954 ); GO:0035306 positive regulation of dephosphorylation ( 0.00195930615245954 ); GO:0035307 positive regulation of protein amino acid dephosphorylation ( 0.00195930615245954 ); GO:0045066 regulatory T cell differentiation ( 0.00195930615245954 ); GO:0051279 regulation of release of sequestered calcium ion into cytosol ( 0.00195930615245954 ); GO:0051897 positive regulation of protein kinase B signaling cascade ( 0.00195930615245954 ); GO:0052173 response to defenses of other organism during symbiotic interaction ( 0.00195930615245954 ); GO:0052200 response to host defenses ( 0.00195930615245954 ); GO:0009205 purine ribonucleoside triphosphate metabolic process ( 0.00207229246859219 ); GO:0009144 purine nucleoside triphosphate metabolic process ( 0.0021113662597118 ); GO:0009199 ribonucleoside triphosphate metabolic process ( 0.0021113662597118 ); GO:0009141 nucleoside triphosphate metabolic process ( 0.00235314918094935 ); GO:0009152 purine ribonucleotide biosynthetic process ( 0.00235314918094935 ); GO:0006164 purine nucleotide biosynthetic process ( 0.00260745263888352 ); GO:0002246 healing during inflammatory response ( 0.00261162033144524 ); GO:0007435 salivary gland morphogenesis ( 0.00261162033144524 ); GO:0010714 positive regulation of collagen metabolic process ( 0.00261162033144524 ); GO:0032967 positive regulation of collagen biosynthetic process ( 0.00261162033144524 ); GO:0033160 positive regulation of protein import into nucleus, translocation ( 0.00261162033144524 ); GO:0035304 regulation of protein amino acid dephosphorylation ( 0.00261162033144524 ); GO:0060390 regulation of SMAD protein nuclear translocation ( 0.00261162033144524 ); GO:0060391 positive regulation of SMAD protein nuclear translocation ( 0.00261162033144524 ); GO:0004301 epoxide hydrolase activity ( 0.00261162033144524 ); GO:0009260 ribonucleotide biosynthetic process ( 0.00269498785684813 ); GO:0009150 purine ribonucleotide metabolic process ( 0.00278390145378154 ); GO:0009259 ribonucleotide metabolic process ( 0.00324903382379017 ); GO:0002507 tolerance induction ( 0.00326354093759373 ); GO:0032965 regulation of collagen biosynthetic process ( 0.00326354093759373 ); GO:0033158 regulation of protein import into nucleus, translocation ( 0.00326354093759373 ); GO:0045830 positive regulation of isotype switching ( 0.00326354093759373 ); GO:0045911 positive regulation of DNA recombination ( 0.00326354093759373 ); GO:0016803 ether hydrolase activity ( 0.00326354093759373 ); GO:0006163 purine nucleotide metabolic process ( 0.00334615098336977 ); GO:0007406 negative regulation of neuroblast proliferation ( 0.00391506818859 ); GO:0007431 salivary gland development ( 0.00391506818859 ); GO:0010712 regulation of collagen metabolic process ( 0.00391506818859 ); GO:0022612 gland morphogenesis ( 0.00391506818859 ); GO:0033135 regulation of peptidyl-serine phosphorylation ( 0.00391506818859 ); GO:0033138 positive regulation of peptidyl-serine phosphorylation ( 0.00391506818859 ); GO:0043011 myeloid dendritic cell differentiation ( 0.00391506818859 ); GO:0043536 positive regulation of blood vessel endothelial cell migration ( 0.00391506818859 ); GO:0043550 regulation of lipid kinase activity ( 0.00391506818859 ); GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity ( 0.00391506818859 ); GO:0005114 type II transforming growth factor beta receptor binding ( 0.00391506818859 ); GO:0008354 germ cell migration ( 0.0045662023020081 ); GO:0018107 peptidyl-threonine phosphorylation ( 0.0045662023020081 ); GO:0035303 regulation of dephosphorylation ( 0.0045662023020081 ); GO:0044253 positive regulation of multicellular organismal metabolic process ( 0.0045662023020081 ); GO:0051896 regulation of protein kinase B signaling cascade ( 0.0045662023020081 ); GO:0051926 negative regulation of calcium ion transport ( 0.0045662023020081 ); GO:0001773 myeloid dendritic cell activation ( 0.00521694349531387 ); GO:0010595 positive regulation of endothelial cell migration ( 0.00521694349531387 ); GO:0043537 negative regulation of blood vessel endothelial cell migration ( 0.00521694349531387 ); GO:0016801 hydrolase activity, acting on ether bonds ( 0.00521694349531387 ); GO:0019048 virus-host interaction ( 0.00586729198586211 ); GO:0032964 collagen biosynthetic process ( 0.00586729198586211 ); GO:0044246 regulation of multicellular organismal metabolic process ( 0.00586729198586211 ); GO:0045191 regulation of isotype switching ( 0.00586729198586211 ); GO:0051209 release of sequestered calcium ion into cytosol ( 0.00586729198586211 ); GO:0051282 regulation of sequestering of calcium ion ( 0.00586729198586211 ); GO:0051283 negative regulation of sequestering of calcium ion ( 0.00586729198586211 ); GO:0005796 Golgi lumen ( 0.00586729198586211 ); GO:0006631 fatty acid metabolic process ( 0.0062067210550971 ); GO:0006183 GTP biosynthetic process ( 0.00651724799090103 ); GO:0006228 UTP biosynthetic process ( 0.00651724799090103 ); GO:0010522 regulation of calcium ion transport into cytosol ( 0.00651724799090103 ); GO:0018210 peptidyl-threonine modification ( 0.00651724799090103 ); GO:0030279 negative regulation of ossification ( 0.00651724799090103 ); GO:0035272 exocrine system development ( 0.00651724799090103 ); GO:0043271 negative regulation of ion transport ( 0.00651724799090103 ); GO:0046051 UTP metabolic process ( 0.00651724799090103 ); GO:0004550 nucleoside diphosphate kinase activity ( 0.00651724799090103 ); GO:0006241 CTP biosynthetic process ( 0.00716681172756617 ); GO:0007096 regulation of exit from mitosis ( 0.00716681172756617 ); GO:0007184 SMAD protein nuclear translocation ( 0.00716681172756617 ); GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process ( 0.00716681172756617 ); GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process ( 0.00716681172756617 ); GO:0043491 protein kinase B signaling cascade ( 0.00716681172756617 ); GO:0045806 negative regulation of endocytosis ( 0.00716681172756617 ); GO:0045930 negative regulation of mitotic cell cycle ( 0.00716681172756617 ); GO:0046036 CTP metabolic process ( 0.00716681172756617 ); GO:0046039 GTP metabolic process ( 0.00716681172756617 ); GO:0050764 regulation of phagocytosis ( 0.00716681172756617 ); GO:0009147 pyrimidine nucleoside triphosphate metabolic process ( 0.00781598341288636 ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( 0.00781598341288636 ); GO:0031575 G1/S transition checkpoint ( 0.00781598341288636 ); GO:0043535 regulation of blood vessel endothelial cell migration ( 0.00781598341288636 ); GO:0050832 defense response to fungus ( 0.00781598341288636 ); GO:0051208 sequestering of calcium ion ( 0.00781598341288636 ); GO:0006897 endocytosis ( 0.00823517914937388 ); GO:0010324 membrane invagination ( 0.00823517914937388 ); GO:0001933 negative regulation of protein amino acid phosphorylation ( 0.00846476326378098 ); GO:0010458 exit from mitosis ( 0.00846476326378098 ); GO:0010596 negative regulation of endothelial cell migration ( 0.00846476326378098 ); GO:0046851 negative regulation of bone remodeling ( 0.00846476326378098 ); GO:0050777 negative regulation of immune response ( 0.00846476326378098 ); GO:0002637 regulation of immunoglobulin production ( 0.00911315149705938 ); GO:0050680 negative regulation of epithelial cell proliferation ( 0.00911315149705938 ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( 0.00911315149705938 ); GO:0030501 positive regulation of bone mineralization ( 0.00976114832942221 ); GO:0032845 negative regulation of homeostatic process ( 0.00976114832942221 ); GO:0034104 negative regulation of tissue remodeling ( 0.00976114832942221 ); GO:0043029 T cell homeostasis ( 0.00976114832942221 ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( 0.00978600070329349 ); ----------------KEGG-------------- hsa00281 Geraniol degradation ( 0.00261162033144524 ); hsa00930 Caprolactam degradation ( 0.0045662023020081 ); hsa00062 Fatty acid elongation in mitochondria ( 0.00651724799090103 ); hsa04010 MAPK signaling pathway ( 0.0125169504785284 ); hsa00650 Butanoate metabolism ( 0.0245575456062225 ); hsa00071 Fatty acid metabolism ( 0.029656092555761 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.029656092555761 ); hsa00310 Lysine degradation ( 0.0321961306277598 ); hsa00380 Tryptophan metabolism ( 0.0321961306277598 ); hsa05213 Endometrial cancer ( 0.0334638467806877 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0397794667100285 ); hsa05211 Renal cell carcinoma ( 0.0441777110054733 ); hsa05212 Pancreatic cancer ( 0.0460569738936297 ); hsa05220 Chronic myeloid leukemia ( 0.0473079203821105 ); ----------------CARTA-------------- tffpathway ( 0.00976114832942221 ); myosinpathway ( 0.0129952690544002 ); ptenpathway ( 0.0168633428923709 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0200760435285406 ); ============================ group2757 ========================= ----------------C2-------------- REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.0084148872458365 ); REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.0084148872458365 ); ----------------C3-------------- ( 0.00468656810489961 ); ----------------C4-------------- ( 0.00721674801105232 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0034230 enkephalin processing ( ); GO:0034231 islet amyloid polypeptide processing ( ); GO:0030070 insulin processing ( ); GO:0016540 protein autoprocessing ( ); GO:0030672 synaptic vesicle membrane ( ); GO:0016486 peptide hormone processing ( ); ----------------GO-------------- GO:0034230 enkephalin processing ( 0.000603227265872364 ); GO:0034231 islet amyloid polypeptide processing ( 0.000603227265872364 ); GO:0030070 insulin processing ( 0.0012061209554366 ); GO:0016540 protein autoprocessing ( 0.00301280224292078 ); GO:0030672 synaptic vesicle membrane ( 0.00481648737635654 ); GO:0016486 peptide hormone processing ( 0.0084148872458365 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2759 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$ATF_B ( 0.00336456569338907 ); V$CREB_Q4_01 ( 0.00392662246474981 ); TGACGTCA_V$ATF3_Q6 ( 0.00473947538364566 ); V$CREBP1_Q2 ( 0.00528383512336159 ); V$ATF1_Q6 ( 0.00545253595978805 ); V$CREB_Q4 ( 0.00550931992886285 ); V$CREB_Q2 ( 0.0057391997216974 ); V$ATF3_Q6 ( 0.0057391997216974 ); V$CREB_01 ( 0.00597345564797725 ); V$CREBP1CJUN_01 ( 0.0060327011959662 ); V$ATF_01 ( 0.00615200811812586 ); V$E4F1_Q6 ( 0.00633300367409797 ); ----------------C4-------------- ( 0.00484612615350782 ); ----------------C5-------------- CATION_TRANSPORTING_ATPASE_ACTIVITY ( 0.00661718087346452 ); REGULATION_OF_JAK_STAT_CASCADE ( 0.00721674801105232 ); REGULATION_OF_CATABOLIC_PROCESS ( 0.00901345967669531 ); ----------------GOSLIM-------------- GO:0008429 phosphatidylethanolamine binding ( ); GO:0046426 negative regulation of JAK-STAT cascade ( ); GO:0033179 proton-transporting V-type ATPase, V0 domain ( ); GO:0005773 vacuole ( ); GO:0005776 autophagic vacuole ( ); GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism ( ); ----------------GO-------------- GO:0008429 phosphatidylethanolamine binding ( 0.0024109082763728 ); GO:0046426 negative regulation of JAK-STAT cascade ( 0.0036143633035145 ); GO:0033179 proton-transporting V-type ATPase, V0 domain ( 0.0036143633035145 ); GO:0005773 vacuole ( 0.00597345564797725 ); GO:0005776 autophagic vacuole ( 0.00601728183317862 ); GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism ( 0.00721674801105232 ); ----------------KEGG-------------- hsa05110 Vibrio cholerae infection ( 0.0344409223443456 ); hsa05120 Epithelial cell signaling in Helicobacter pylori infection ( 0.0396866654970505 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2790 ========================= ----------------C2-------------- ( 0.00721674801105232 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- SMOOTH_MUSCLE_CONTRACTION_GO_0006939 ( 0.00721674801105232 ); INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHODIESTERASE_ACTIVITY ( 0.00781598341288636 ); CALCIUM_MEDIATED_SIGNALING ( 0.0084148872458365 ); PHOSPHOLIPASE_C_ACTIVITY ( 0.00901345967669531 ); ----------------GOSLIM-------------- GO:0010455 positive regulation of cell fate commitment ( ); GO:0032793 positive regulation of CREB transcription factor activity ( ); GO:0010453 regulation of cell fate commitment ( ); GO:0010454 negative regulation of cell fate commitment ( ); GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification ( ); GO:0022010 myelination in the central nervous system ( ); GO:0032291 ensheathment of axons in the central nervous system ( ); GO:0032835 glomerulus development ( ); GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification ( ); GO:0048644 muscle morphogenesis ( ); GO:0006651 diacylglycerol biosynthetic process ( ); GO:0010828 positive regulation of glucose transport ( ); GO:0021514 ventral spinal cord interneuron differentiation ( ); GO:0021521 ventral spinal cord interneuron specification ( ); GO:0046326 positive regulation of glucose import ( ); GO:0021520 spinal cord motor neuron cell fate specification ( ); GO:0021904 dorsoventral neural tube patterning ( ); GO:0043565 sequence-specific DNA binding ( ); GO:0014015 positive regulation of gliogenesis ( ); GO:0045687 positive regulation of glial cell differentiation ( ); GO:0014014 negative regulation of gliogenesis ( ); GO:0032024 positive regulation of insulin secretion ( ); GO:0045686 negative regulation of glial cell differentiation ( ); GO:0046339 diacylglycerol metabolic process ( ); GO:0048016 inositol phosphate-mediated signaling ( ); GO:0000122 negative regulation of transcription from RNA polymerase II promoter ( ); GO:0021532 neural tube patterning ( ); GO:0031532 actin cytoskeleton reorganization ( ); GO:0032869 cellular response to insulin stimulus ( ); GO:0046460 neutral lipid biosynthetic process ( ); GO:0046463 acylglycerol biosynthetic process ( ); GO:0008301 DNA bending activity ( ); GO:0002793 positive regulation of peptide secretion ( ); GO:0014003 oligodendrocyte development ( ); GO:0014013 regulation of gliogenesis ( ); GO:0021522 spinal cord motor neuron differentiation ( ); GO:0045017 glycerolipid biosynthetic process ( ); GO:0045685 regulation of glial cell differentiation ( ); GO:0046324 regulation of glucose import ( ); GO:0046504 glycerol ether biosynthetic process ( ); GO:0032502 developmental process ( ); GO:0010827 regulation of glucose transport ( ); GO:0021517 ventral spinal cord development ( ); GO:0046323 glucose import ( ); GO:0048665 neuron fate specification ( ); GO:0010646 regulation of cell communication ( ); GO:0000155 two-component sensor activity ( ); GO:0004673 protein histidine kinase activity ( ); GO:0004198 calcium-dependent cysteine-type endopeptidase activity ( ); GO:0007275 multicellular organismal development ( ); GO:0031018 endocrine pancreas development ( ); GO:0032870 cellular response to hormone stimulus ( ); GO:0045892 negative regulation of transcription, DNA-dependent ( ); GO:0021782 glial cell development ( ); GO:0051253 negative regulation of RNA metabolic process ( ); ----------------GO-------------- GO:0010455 positive regulation of cell fate commitment ( 0.000603227265872364 ); GO:0032793 positive regulation of CREB transcription factor activity ( 0.000603227265872364 ); GO:0010453 regulation of cell fate commitment ( 0.0012061209554366 ); GO:0010454 negative regulation of cell fate commitment ( 0.0012061209554366 ); GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification ( 0.0012061209554366 ); GO:0022010 myelination in the central nervous system ( 0.0012061209554366 ); GO:0032291 ensheathment of axons in the central nervous system ( 0.0012061209554366 ); GO:0032835 glomerulus development ( 0.0012061209554366 ); GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification ( 0.00180868123639466 ); GO:0048644 muscle morphogenesis ( 0.00180868123639466 ); GO:0006651 diacylglycerol biosynthetic process ( 0.0024109082763728 ); GO:0010828 positive regulation of glucose transport ( 0.0024109082763728 ); GO:0021514 ventral spinal cord interneuron differentiation ( 0.0024109082763728 ); GO:0021521 ventral spinal cord interneuron specification ( 0.0024109082763728 ); GO:0046326 positive regulation of glucose import ( 0.0024109082763728 ); GO:0021520 spinal cord motor neuron cell fate specification ( 0.00301280224292078 ); GO:0021904 dorsoventral neural tube patterning ( 0.00301280224292078 ); GO:0043565 sequence-specific DNA binding ( 0.00311808315311529 ); GO:0014015 positive regulation of gliogenesis ( 0.0036143633035145 ); GO:0045687 positive regulation of glial cell differentiation ( 0.0036143633035145 ); GO:0014014 negative regulation of gliogenesis ( 0.00421559162555196 ); GO:0032024 positive regulation of insulin secretion ( 0.00421559162555196 ); GO:0045686 negative regulation of glial cell differentiation ( 0.00421559162555196 ); GO:0046339 diacylglycerol metabolic process ( 0.00481648737635654 ); GO:0048016 inositol phosphate-mediated signaling ( 0.00481648737635654 ); GO:0000122 negative regulation of transcription from RNA polymerase II promoter ( 0.00489986904924639 ); GO:0021532 neural tube patterning ( 0.005417050723175 ); GO:0031532 actin cytoskeleton reorganization ( 0.00601728183317862 ); GO:0032869 cellular response to insulin stimulus ( 0.00601728183317862 ); GO:0046460 neutral lipid biosynthetic process ( 0.00601728183317862 ); GO:0046463 acylglycerol biosynthetic process ( 0.00601728183317862 ); GO:0008301 DNA bending activity ( 0.00601728183317862 ); GO:0002793 positive regulation of peptide secretion ( 0.00661718087346452 ); GO:0014003 oligodendrocyte development ( 0.00661718087346452 ); GO:0014013 regulation of gliogenesis ( 0.00661718087346452 ); GO:0021522 spinal cord motor neuron differentiation ( 0.00661718087346452 ); GO:0045017 glycerolipid biosynthetic process ( 0.00661718087346452 ); GO:0045685 regulation of glial cell differentiation ( 0.00661718087346452 ); GO:0046324 regulation of glucose import ( 0.00661718087346452 ); GO:0046504 glycerol ether biosynthetic process ( 0.00661718087346452 ); GO:0032502 developmental process ( 0.00689812028557193 ); GO:0010827 regulation of glucose transport ( 0.00721674801105232 ); GO:0021517 ventral spinal cord development ( 0.00721674801105232 ); GO:0046323 glucose import ( 0.00721674801105232 ); GO:0048665 neuron fate specification ( 0.00721674801105232 ); GO:0010646 regulation of cell communication ( 0.00731813153870822 ); GO:0000155 two-component sensor activity ( 0.00781598341288636 ); GO:0004673 protein histidine kinase activity ( 0.00781598341288636 ); GO:0004198 calcium-dependent cysteine-type endopeptidase activity ( 0.0084148872458365 ); GO:0007275 multicellular organismal development ( 0.00854781903506759 ); GO:0031018 endocrine pancreas development ( 0.00901345967669531 ); GO:0032870 cellular response to hormone stimulus ( 0.00901345967669531 ); GO:0045892 negative regulation of transcription, DNA-dependent ( 0.00933577734389132 ); GO:0021782 glial cell development ( 0.00961170087218188 ); GO:0051253 negative regulation of RNA metabolic process ( 0.00970209888573322 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.0285815205489298 ); hsa04070 Phosphatidylinositol signaling system ( 0.0449062723926186 ); ----------------CARTA-------------- ( 0.0220985450630776 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2902 ========================= ----------------C2-------------- BIOCARTA_NEUROTRANSMITTERS_PATHWAY ( 0.0036143633035145 ); REACTOME_AMINE_DERIVED_HORMONES ( 0.00721674801105232 ); REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.00721674801105232 ); ----------------C3-------------- ( 0.00639387706885688 ); ----------------C4-------------- module_49 ( 0.00897589670472518 ); module_141 ( 0.00961170087218188 ); ----------------C5-------------- BODY_FLUID_SECRETION ( 0.00601728183317862 ); PHOSPHOLIPASE_A2_ACTIVITY ( 0.00721674801105232 ); PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00781598341288636 ); ----------------GOSLIM-------------- GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity ( ); GO:0004500 dopamine beta-monooxygenase activity ( ); GO:0015321 sodium-dependent phosphate transmembrane transporter activity ( ); GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ( ); GO:0006817 phosphate transport ( ); GO:0006548 histidine catabolic process ( ); GO:0009077 histidine family amino acid catabolic process ( ); GO:0042423 catecholamine biosynthetic process ( ); GO:0006547 histidine metabolic process ( ); GO:0009075 histidine family amino acid metabolic process ( ); GO:0015114 phosphate transmembrane transporter activity ( ); GO:0004012 phospholipid-translocating ATPase activity ( ); GO:0015247 aminophospholipid transporter activity ( ); GO:0035250 UDP-galactosyltransferase activity ( ); ----------------GO-------------- GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity ( 0.000603227265872364 ); GO:0004500 dopamine beta-monooxygenase activity ( 0.0024109082763728 ); GO:0015321 sodium-dependent phosphate transmembrane transporter activity ( 0.00301280224292078 ); GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ( 0.00301280224292078 ); GO:0006817 phosphate transport ( 0.00481648737635654 ); GO:0006548 histidine catabolic process ( 0.005417050723175 ); GO:0009077 histidine family amino acid catabolic process ( 0.005417050723175 ); GO:0042423 catecholamine biosynthetic process ( 0.005417050723175 ); GO:0006547 histidine metabolic process ( 0.00661718087346452 ); GO:0009075 histidine family amino acid metabolic process ( 0.00661718087346452 ); GO:0015114 phosphate transmembrane transporter activity ( 0.00781598341288636 ); GO:0004012 phospholipid-translocating ATPase activity ( 0.00901345967669531 ); GO:0015247 aminophospholipid transporter activity ( 0.00901345967669531 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00961170087218188 ); ----------------KEGG-------------- hsa00592 alpha-Linolenic acid metabolism ( 0.00961170087218188 ); hsa00591 Linoleic acid metabolism ( 0.0167648194413575 ); hsa00565 Ether lipid metabolism ( 0.0191386477389445 ); hsa00350 Tyrosine metabolism ( 0.0268173548432519 ); hsa00590 Arachidonic acid metabolism ( 0.0321010604416693 ); hsa00564 Glycerophospholipid metabolism ( 0.0385232076647145 ); hsa04370 VEGF signaling pathway ( 0.0431693001351721 ); hsa04730 Long-term depression ( 0.0437486123651611 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0449062723926186 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2919 ========================= ----------------C2-------------- ( 0.00781598341288636 ); ----------------C3-------------- ( 0.00533979326162223 ); ----------------C4-------------- ( ); ----------------C5-------------- PEPTIDASE_ACTIVITY ( 0.00452952227002282 ); SMALL_CONJUGATING_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY ( 0.00601728183317862 ); ----------------GOSLIM-------------- GO:0010756 positive regulation of plasminogen activation ( 0.00126874577314142 ); GO:0051788 response to misfolded protein ( 0.00126874577314142 ); GO:0051787 misfolded protein binding ( 0.00126874577314142 ); GO:0002254 kinin cascade ( 0.00126874577314142 ); GO:0002353 plasma kallikrein-kinin cascade ( 0.00126874577314142 ); GO:0002542 Factor XII activation ( 0.00126874577314142 ); GO:0007597 blood coagulation, intrinsic pathway ( 0.00126874577314142 ); GO:0010755 regulation of plasminogen activation ( 0.00126874577314142 ); GO:0033872 [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity ( 0.00126874577314142 ); GO:0051919 positive regulation of fibrinolysis ( 0.00126874577314142 ); GO:0016540 protein autoprocessing ( 0.00126874577314142 ); GO:0030194 positive regulation of blood coagulation ( 0.00126874577314142 ); GO:0050820 positive regulation of coagulation ( 0.00126874577314142 ); GO:0031639 plasminogen activation ( 0.00126874577314142 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00126874577314142 ); GO:0031638 zymogen activation ( 0.00126874577314142 ); GO:0051917 regulation of fibrinolysis ( 0.00126874577314142 ); GO:0034483 heparan sulfate sulfotransferase activity ( 0.00126874577314142 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00126874577314142 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00126874577314142 ); GO:0043227 membrane-bounded organelle ( 0.00126874577314142 ); GO:0045892 negative regulation of transcription, DNA-dependent ( 0.00126874577314142 ); GO:0051253 negative regulation of RNA metabolic process ( 0.00126874577314142 ); ----------------GO-------------- GO:0010756 positive regulation of plasminogen activation ( 0.000603227265872364 ); GO:0051788 response to misfolded protein ( 0.000603227265872364 ); GO:0051787 misfolded protein binding ( 0.000603227265872364 ); GO:0002254 kinin cascade ( 0.0012061209554366 ); GO:0002353 plasma kallikrein-kinin cascade ( 0.0012061209554366 ); GO:0002542 Factor XII activation ( 0.0012061209554366 ); GO:0007597 blood coagulation, intrinsic pathway ( 0.0012061209554366 ); GO:0010755 regulation of plasminogen activation ( 0.0012061209554366 ); GO:0033872 [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity ( 0.0012061209554366 ); GO:0051919 positive regulation of fibrinolysis ( 0.0024109082763728 ); GO:0016540 protein autoprocessing ( 0.00301280224292078 ); GO:0030194 positive regulation of blood coagulation ( 0.00301280224292078 ); GO:0050820 positive regulation of coagulation ( 0.00301280224292078 ); GO:0031639 plasminogen activation ( 0.0036143633035145 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.0036143633035145 ); GO:0031638 zymogen activation ( 0.00481648737635654 ); GO:0051917 regulation of fibrinolysis ( 0.00481648737635654 ); GO:0034483 heparan sulfate sulfotransferase activity ( 0.00601728183317862 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00661718087346452 ); GO:0043231 intracellular membrane-bounded organelle ( 0.00838191937018058 ); GO:0043227 membrane-bounded organelle ( 0.00840775677906687 ); GO:0045892 negative regulation of transcription, DNA-dependent ( 0.00933577734389132 ); GO:0051253 negative regulation of RNA metabolic process ( 0.00970209888573322 ); ----------------KEGG-------------- hsa00534 Heparan sulfate biosynthesis ( 0.0114044387124531 ); hsa03030 DNA replication ( 0.0215072214319739 ); hsa04920 Adipocytokine signaling pathway ( 0.0391050979969726 ); hsa04610 Complement and coagulation cascades ( 0.0402679103277791 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.00032417786831526 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3003 ========================= ----------------C2-------------- ( 0.00354734765972743 ); ----------------C3-------------- TGAYRTCA_V$ATF3_Q6 ( 0.00156205084637265 ); TGACGTCA_V$ATF3_Q6 ( 0.00473947538364566 ); V$CREB_Q4 ( 0.00550931992886285 ); V$CREB_Q2 ( 0.0057391997216974 ); V$CREB_01 ( 0.00597345564797725 ); V$CREBP1CJUN_01 ( 0.0060327011959662 ); V$GATA_C ( 0.00633300367409797 ); GATAAGR_V$GATA_C ( 0.0081386744116943 ); ----------------C4-------------- ( ); ----------------C5-------------- POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.00601728183317862 ); SMALL_CONJUGATING_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY ( 0.00601728183317862 ); REGULATION_OF_PROTEIN_POLYMERIZATION ( 0.00661718087346452 ); REGULATION_OF_ACTIN_POLYMERIZATION_AND_OR_DEPOLYMERIZATION ( 0.00721674801105232 ); REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00781598341288636 ); REGULATION_OF_ACTIN_FILAMENT_LENGTH ( 0.00781598341288636 ); ACTIN_FILAMENT_POLYMERIZATION ( 0.0084148872458365 ); REGULATION_OF_CELLULAR_COMPONENT_SIZE ( 0.0084148872458365 ); REGULATION_OF_ENDOCYTOSIS ( 0.00901345967669531 ); ----------------GOSLIM-------------- GO:0016929 SUMO-specific protease activity ( ); GO:0018112 proline racemase activity ( ); GO:0016926 protein desumoylation ( ); GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives ( ); GO:0016055 Wnt receptor signaling pathway ( ); GO:0048261 negative regulation of receptor-mediated endocytosis ( ); GO:0030838 positive regulation of actin filament polymerization ( ); GO:0031529 ruffle organization ( ); GO:0001832 blastocyst growth ( ); GO:0035020 regulation of Rac protein signal transduction ( ); GO:0030866 cortical actin cytoskeleton organization ( ); GO:0030865 cortical cytoskeleton organization ( ); GO:0045806 negative regulation of endocytosis ( ); GO:0032273 positive regulation of protein polymerization ( ); GO:0048259 regulation of receptor-mediated endocytosis ( ); GO:0016854 racemase and epimerase activity ( ); GO:0016601 Rac protein signal transduction ( ); GO:0031334 positive regulation of protein complex assembly ( ); ----------------GO-------------- GO:0016929 SUMO-specific protease activity ( 0.000603227265872364 ); GO:0018112 proline racemase activity ( 0.000603227265872364 ); GO:0016926 protein desumoylation ( 0.0012061209554366 ); GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives ( 0.0012061209554366 ); GO:0016055 Wnt receptor signaling pathway ( 0.0026392538541617 ); GO:0048261 negative regulation of receptor-mediated endocytosis ( 0.00301280224292078 ); GO:0030838 positive regulation of actin filament polymerization ( 0.0036143633035145 ); GO:0031529 ruffle organization ( 0.0036143633035145 ); GO:0001832 blastocyst growth ( 0.00421559162555196 ); GO:0035020 regulation of Rac protein signal transduction ( 0.00421559162555196 ); GO:0030866 cortical actin cytoskeleton organization ( 0.00601728183317862 ); GO:0030865 cortical cytoskeleton organization ( 0.00661718087346452 ); GO:0045806 negative regulation of endocytosis ( 0.00661718087346452 ); GO:0032273 positive regulation of protein polymerization ( 0.00721674801105232 ); GO:0048259 regulation of receptor-mediated endocytosis ( 0.00721674801105232 ); GO:0016854 racemase and epimerase activity ( 0.00721674801105232 ); GO:0016601 Rac protein signal transduction ( 0.00781598341288636 ); GO:0031334 positive regulation of protein complex assembly ( 0.00901345967669531 ); ----------------KEGG-------------- hsa04310 Wnt signaling pathway ( 0.00359375902467358 ); hsa04340 Hedgehog signaling pathway ( 0.0338564434837793 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- TIAL1_iCLIP_(Wang_2010) ( 0.0293410064682329 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0499056682453975 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3007 ========================= ----------------C2-------------- KEGG_ENDOCYTOSIS ( 0.00500818837544879 ); BIOCARTA_RNA_PATHWAY ( 0.00601728183317862 ); REACTOME_ERKS_ARE_INACTIVATED ( 0.00721674801105232 ); KEGG_NON_HOMOLOGOUS_END_JOINING ( 0.00781598341288636 ); BIOCARTA_TALL1_PATHWAY ( 0.0084148872458365 ); KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE ( 0.00901345967669531 ); BIOCARTA_CD40_PATHWAY ( 0.00901345967669531 ); ----------------C3-------------- V$MTF1_Q4 ( 0.000166291881985281 ); V$USF_Q6_01 ( 0.00427338380047511 ); V$ZF5_B ( 0.00517274674710693 ); V$SREBP1_Q6 ( 0.00579735417608064 ); V$ROAZ_01 ( 0.00601728183317862 ); CTTTGCA,MIR-527 ( 0.00615200811812586 ); ----------------C4-------------- module_169 ( 0.00141379067532188 ); module_540 ( 0.00601728183317862 ); ----------------C5-------------- VESICLE_MEDIATED_TRANSPORT ( 0.00545253595978805 ); REGULATION_OF_RHO_GTPASE_ACTIVITY ( 0.00601728183317862 ); REGULATION_OF_RAS_GTPASE_ACTIVITY ( 0.00661718087346452 ); CDC42_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00721674801105232 ); REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00781598341288636 ); REGULATION_OF_GTPASE_ACTIVITY ( 0.0084148872458365 ); SH3_DOMAIN_BINDING ( 0.00901345967669531 ); GALACTOSYLTRANSFERASE_ACTIVITY ( 0.00901345967669531 ); RHO_GTPASE_ACTIVATOR_ACTIVITY ( 0.00961170087218188 ); ----------------GOSLIM-------------- GO:0019904 protein domain specific binding ( 0.00597550793046253 ); GO:0005515 protein binding ( 0.00883544988368029 ); GO:0000815 ESCRT III complex ( 0.00997066717373536 ); GO:0005488 binding ( 0.00597550793046253 ); GO:0002566 somatic diversification of immune receptors via somatic mutation ( 0.00883544988368029 ); GO:0016446 somatic hypermutation of immunoglobulin genes ( 0.00997066717373536 ); GO:0043089 positive regulation of Cdc42 GTPase activity ( 0.00597550793046253 ); GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity ( 0.00883544988368029 ); GO:0004461 lactose synthase activity ( 0.00997066717373536 ); GO:0032489 regulation of Cdc42 protein signal transduction ( 0.00597550793046253 ); GO:0043088 regulation of Cdc42 GTPase activity ( 0.00883544988368029 ); GO:0005916 fascia adherens ( 0.00997066717373536 ); GO:0003945 N-acetyllactosamine synthase activity ( 0.00597550793046253 ); GO:0010008 endosome membrane ( 0.00883544988368029 ); GO:0044440 endosomal part ( 0.00997066717373536 ); GO:0016192 vesicle-mediated transport ( 0.00597550793046253 ); GO:0030145 manganese ion binding ( 0.00883544988368029 ); GO:0014704 intercalated disc ( 0.00997066717373536 ); GO:0030675 Rac GTPase activator activity ( 0.00597550793046253 ); GO:0032321 positive regulation of Rho GTPase activity ( 0.00883544988368029 ); GO:0032488 Cdc42 protein signal transduction ( 0.00997066717373536 ); GO:0006878 cellular copper ion homeostasis ( 0.00597550793046253 ); GO:0030057 desmosome ( 0.00883544988368029 ); GO:0032320 positive regulation of Ras GTPase activity ( 0.00997066717373536 ); GO:0055070 copper ion homeostasis ( 0.00597550793046253 ); GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity ( 0.00883544988368029 ); GO:0033549 MAP kinase phosphatase activity ( 0.00997066717373536 ); GO:0043547 positive regulation of GTPase activity ( 0.00597550793046253 ); GO:0030496 midbody ( 0.00883544988368029 ); GO:0006897 endocytosis ( 0.00997066717373536 ); GO:0010324 membrane invagination ( 0.00597550793046253 ); GO:0032319 regulation of Rho GTPase activity ( 0.00883544988368029 ); GO:0009898 internal side of plasma membrane ( 0.00997066717373536 ); GO:0050699 WW domain binding ( 0.00597550793046253 ); GO:0005768 endosome ( 0.00883544988368029 ); GO:0004709 MAP kinase kinase kinase activity ( 0.00997066717373536 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00597550793046253 ); ----------------GO-------------- GO:0019904 protein domain specific binding ( 0.000261899781744525 ); GO:0005515 protein binding ( 0.000969718149710076 ); GO:0000815 ESCRT III complex ( 0.0012061209554366 ); GO:0005488 binding ( 0.00145488875157603 ); GO:0002566 somatic diversification of immune receptors via somatic mutation ( 0.00180868123639466 ); GO:0016446 somatic hypermutation of immunoglobulin genes ( 0.00180868123639466 ); GO:0043089 positive regulation of Cdc42 GTPase activity ( 0.00180868123639466 ); GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity ( 0.00180868123639466 ); GO:0004461 lactose synthase activity ( 0.00180868123639466 ); GO:0032489 regulation of Cdc42 protein signal transduction ( 0.0024109082763728 ); GO:0043088 regulation of Cdc42 GTPase activity ( 0.0024109082763728 ); GO:0005916 fascia adherens ( 0.0024109082763728 ); GO:0003945 N-acetyllactosamine synthase activity ( 0.0024109082763728 ); GO:0010008 endosome membrane ( 0.00267959433544673 ); GO:0044440 endosomal part ( 0.00272022696328311 ); GO:0016192 vesicle-mediated transport ( 0.00296502387390841 ); GO:0030145 manganese ion binding ( 0.00323049438287401 ); GO:0014704 intercalated disc ( 0.00421559162555196 ); GO:0030675 Rac GTPase activator activity ( 0.00421559162555196 ); GO:0032321 positive regulation of Rho GTPase activity ( 0.00481648737635654 ); GO:0032488 Cdc42 protein signal transduction ( 0.00481648737635654 ); GO:0006878 cellular copper ion homeostasis ( 0.005417050723175 ); GO:0030057 desmosome ( 0.005417050723175 ); GO:0032320 positive regulation of Ras GTPase activity ( 0.00601728183317862 ); GO:0055070 copper ion homeostasis ( 0.00601728183317862 ); GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity ( 0.00601728183317862 ); GO:0033549 MAP kinase phosphatase activity ( 0.00601728183317862 ); GO:0043547 positive regulation of GTPase activity ( 0.00661718087346452 ); GO:0030496 midbody ( 0.00661718087346452 ); GO:0006897 endocytosis ( 0.00701742857973733 ); GO:0010324 membrane invagination ( 0.00701742857973733 ); GO:0032319 regulation of Rho GTPase activity ( 0.00721674801105232 ); GO:0009898 internal side of plasma membrane ( 0.00721674801105232 ); GO:0050699 WW domain binding ( 0.00781598341288636 ); GO:0005768 endosome ( 0.00883375583705215 ); GO:0004709 MAP kinase kinase kinase activity ( 0.00901345967669531 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00961170087218188 ); ----------------KEGG-------------- hsa00791 Atrazine degradation ( 0.005417050723175 ); hsa03450 Non-homologous end-joining ( 0.00781598341288636 ); hsa00533 Keratan sulfate biosynthesis ( 0.00961170087218188 ); hsa04010 MAPK signaling pathway ( 0.0106844252237892 ); hsa00052 Galactose metabolism ( 0.0149809935109184 ); hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series ( 0.015575931505577 ); hsa03410 Base excision repair ( 0.0203235907495731 ); hsa00510 N-Glycan biosynthesis ( 0.0250502527179502 ); hsa05221 Acute myeloid leukemia ( 0.0332716403222059 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0373584578519528 ); hsa05120 Epithelial cell signaling in Helicobacter pylori infection ( 0.0396866654970505 ); ----------------CARTA-------------- ( 0.0167648194413575 ); ----------------RBP-------------- ( 0.00248737578522912 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3018 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$PBX1_01 ( 0.00539602697227046 ); TCCGTCC,MIR-184 ( 0.00601728183317862 ); CACTTTG,MIR-520G,MIR-520H ( 0.00633300367409797 ); ----------------C4-------------- module_107 ( 0.000951815129766999 ); module_209 ( 0.00118537533506062 ); module_172 ( 0.0013841737505539 ); module_231 ( 0.005417050723175 ); module_402 ( 0.00721674801105232 ); ----------------C5-------------- ANATOMICAL_STRUCTURE_DEVELOPMENT ( 0.00226230334599571 ); NEUTRAL_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00721674801105232 ); PLASMA_MEMBRANE ( 0.00730668938377586 ); REGULATION_OF_HOMEOSTATIC_PROCESS ( 0.00781598341288636 ); SOLUTE_SODIUM_SYMPORTER_ACTIVITY ( 0.00781598341288636 ); NUCLEOTIDE_KINASE_ACTIVITY ( 0.00781598341288636 ); ----------------GOSLIM-------------- GO:0030073 insulin secretion ( 0.00387821724291245 ); GO:0002790 peptide secretion ( 0.00387821724291245 ); GO:0030072 peptide hormone secretion ( 0.00387821724291245 ); GO:0046879 hormone secretion ( 0.00387821724291245 ); GO:0015833 peptide transport ( 0.00387821724291245 ); GO:0009914 hormone transport ( 0.00387821724291245 ); GO:0030900 forebrain development ( 0.00387821724291245 ); GO:0031017 exocrine pancreas development ( 0.00387821724291245 ); GO:0015375 glycine:sodium symporter activity ( 0.00387821724291245 ); GO:0003001 generation of a signal involved in cell-cell signaling ( 0.00387821724291245 ); GO:0045780 positive regulation of bone resorption ( 0.00387821724291245 ); GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity ( 0.00387821724291245 ); GO:0004977 melanocortin receptor activity ( 0.00387821724291245 ); GO:0015187 glycine transmembrane transporter activity ( 0.00387821724291245 ); GO:0007409 axonogenesis ( 0.00387821724291245 ); GO:0010817 regulation of hormone levels ( 0.00387821724291245 ); GO:0048812 neurite morphogenesis ( 0.00387821724291245 ); GO:0048667 cell morphogenesis involved in neuron differentiation ( 0.00387821724291245 ); GO:0032990 cell part morphogenesis ( 0.00387821724291245 ); GO:0048858 cell projection morphogenesis ( 0.00387821724291245 ); GO:0009653 anatomical structure morphogenesis ( 0.00387821724291245 ); GO:0000904 cell morphogenesis involved in differentiation ( 0.00387821724291245 ); GO:0031175 neurite development ( 0.00387821724291245 ); GO:0004017 adenylate kinase activity ( 0.00387821724291245 ); GO:0005283 sodium:amino acid symporter activity ( 0.00387821724291245 ); GO:0030280 structural constituent of epidermis ( 0.00387821724291245 ); GO:0007420 brain development ( 0.00387821724291245 ); GO:0045124 regulation of bone resorption ( 0.00387821724291245 ); GO:0048856 anatomical structure development ( 0.00387821724291245 ); GO:0032846 positive regulation of homeostatic process ( 0.00387821724291245 ); GO:0035272 exocrine system development ( 0.00387821724291245 ); GO:0005416 cation:amino acid symporter activity ( 0.00387821724291245 ); GO:0048666 neuron development ( 0.00387821724291245 ); GO:0007263 nitric oxide mediated signal transduction ( 0.00387821724291245 ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( 0.00387821724291245 ); GO:0019206 nucleoside kinase activity ( 0.00387821724291245 ); GO:0031018 endocrine pancreas development ( 0.00387821724291245 ); GO:0030030 cell projection organization ( 0.00387821724291245 ); ----------------GO-------------- GO:0030073 insulin secretion ( 0.000196294562747541 ); GO:0002790 peptide secretion ( 0.00032551492871616 ); GO:0030072 peptide hormone secretion ( 0.00032551492871616 ); GO:0046879 hormone secretion ( 0.00046909993966175 ); GO:0015833 peptide transport ( 0.000504493257569722 ); GO:0009914 hormone transport ( 0.000559948406945495 ); GO:0030900 forebrain development ( 0.00113132385442296 ); GO:0031017 exocrine pancreas development ( 0.0012061209554366 ); GO:0015375 glycine:sodium symporter activity ( 0.0012061209554366 ); GO:0003001 generation of a signal involved in cell-cell signaling ( 0.00124065028673827 ); GO:0045780 positive regulation of bone resorption ( 0.00180868123639466 ); GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity ( 0.00180868123639466 ); GO:0004977 melanocortin receptor activity ( 0.00301280224292078 ); GO:0015187 glycine transmembrane transporter activity ( 0.00301280224292078 ); GO:0007409 axonogenesis ( 0.00318637988386892 ); GO:0010817 regulation of hormone levels ( 0.0034098310545119 ); GO:0048812 neurite morphogenesis ( 0.00354734765972743 ); GO:0048667 cell morphogenesis involved in neuron differentiation ( 0.00364045613304516 ); GO:0032990 cell part morphogenesis ( 0.00378225889384282 ); GO:0048858 cell projection morphogenesis ( 0.00378225889384282 ); GO:0009653 anatomical structure morphogenesis ( 0.00382949966864457 ); GO:0000904 cell morphogenesis involved in differentiation ( 0.00468656810489961 ); GO:0031175 neurite development ( 0.00479266149911254 ); GO:0004017 adenylate kinase activity ( 0.00481648737635654 ); GO:0005283 sodium:amino acid symporter activity ( 0.00481648737635654 ); GO:0030280 structural constituent of epidermis ( 0.00481648737635654 ); GO:0007420 brain development ( 0.00511761710118073 ); GO:0045124 regulation of bone resorption ( 0.005417050723175 ); GO:0048856 anatomical structure development ( 0.00585941685545204 ); GO:0032846 positive regulation of homeostatic process ( 0.00601728183317862 ); GO:0035272 exocrine system development ( 0.00601728183317862 ); GO:0005416 cation:amino acid symporter activity ( 0.00661718087346452 ); GO:0048666 neuron development ( 0.00766771779856396 ); GO:0007263 nitric oxide mediated signal transduction ( 0.00781598341288636 ); GO:0045944 positive regulation of transcription from RNA polymerase II promoter ( 0.00834445584567968 ); GO:0019206 nucleoside kinase activity ( 0.0084148872458365 ); GO:0031018 endocrine pancreas development ( 0.00901345967669531 ); GO:0030030 cell projection organization ( 0.00999976983034982 ); ----------------KEGG-------------- hsa04950 Maturity onset diabetes of the young ( 0.0137901286386202 ); hsa04930 Type II diabetes mellitus ( 0.0244605653708031 ); hsa04330 Notch signaling pathway ( 0.0268173548432519 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3093 ========================= ----------------C2-------------- ( 0.00601728183317862 ); ----------------C3-------------- V$YY1_01 ( 0.00562371163146519 ); CACTTTG,MIR-520G,MIR-520H ( 0.00633300367409797 ); V$TFIIA_Q6 ( 0.00651643442003863 ); CCCNNGGGAR_V$OLF1_01 ( 0.00855259184308142 ); CTTTAAR_UNKNOWN ( 0.0085758951223419 ); ----------------C4-------------- ( 0.00901345967669531 ); ----------------C5-------------- KINASE_ACTIVITY ( 0.00111787172676701 ); TRANSFERASE_ACTIVITY__TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS ( 0.00168813897215505 ); ATP_BINDING ( 0.00354734765972743 ); ADENYL_RIBONUCLEOTIDE_BINDING ( 0.00387821724291245 ); ADENYL_NUCLEOTIDE_BINDING ( 0.00412307663876135 ); PURINE_RIBONUCLEOTIDE_BINDING ( 0.00615200811812586 ); PURINE_NUCLEOTIDE_BINDING ( 0.00645502074811248 ); NUCLEOTIDE_BINDING ( 0.00727435196493892 ); GLAND_DEVELOPMENT ( 0.00781598341288636 ); ----------------GOSLIM-------------- GO:0004618 phosphoglycerate kinase activity ( ); GO:0032448 DNA hairpin binding ( ); GO:0030277 maintenance of gastrointestinal epithelium ( ); GO:0033144 negative regulation of steroid hormone receptor signaling pathway ( ); GO:0033327 Leydig cell differentiation ( ); GO:0017163 basal transcription repressor activity ( ); GO:0033143 regulation of steroid hormone receptor signaling pathway ( ); GO:0060008 Sertoli cell differentiation ( ); GO:0016774 phosphotransferase activity, carboxyl group as acceptor ( ); GO:0042788 polysomal ribosome ( ); GO:0004111 creatine kinase activity ( ); GO:0021854 hypothalamus development ( ); GO:0030325 adrenal gland development ( ); GO:0000217 DNA secondary structure binding ( ); GO:0003706 ligand-regulated transcription factor activity ( ); GO:0006599 phosphagen metabolic process ( ); GO:0006600 creatine metabolic process ( ); GO:0030238 male sex determination ( ); GO:0016301 kinase activity ( ); GO:0005844 polysome ( ); GO:0021983 pituitary gland development ( ); ----------------GO-------------- GO:0004618 phosphoglycerate kinase activity ( 0.000603227265872364 ); GO:0032448 DNA hairpin binding ( 0.000603227265872364 ); GO:0030277 maintenance of gastrointestinal epithelium ( 0.0012061209554366 ); GO:0033144 negative regulation of steroid hormone receptor signaling pathway ( 0.0012061209554366 ); GO:0033327 Leydig cell differentiation ( 0.0012061209554366 ); GO:0017163 basal transcription repressor activity ( 0.0012061209554366 ); GO:0033143 regulation of steroid hormone receptor signaling pathway ( 0.00180868123639466 ); GO:0060008 Sertoli cell differentiation ( 0.00180868123639466 ); GO:0016774 phosphotransferase activity, carboxyl group as acceptor ( 0.00180868123639466 ); GO:0042788 polysomal ribosome ( 0.0024109082763728 ); GO:0004111 creatine kinase activity ( 0.0024109082763728 ); GO:0021854 hypothalamus development ( 0.0036143633035145 ); GO:0030325 adrenal gland development ( 0.0036143633035145 ); GO:0000217 DNA secondary structure binding ( 0.00421559162555196 ); GO:0003706 ligand-regulated transcription factor activity ( 0.00481648737635654 ); GO:0006599 phosphagen metabolic process ( 0.005417050723175 ); GO:0006600 creatine metabolic process ( 0.005417050723175 ); GO:0030238 male sex determination ( 0.005417050723175 ); GO:0016301 kinase activity ( 0.00779463977527295 ); GO:0005844 polysome ( 0.00781598341288636 ); GO:0021983 pituitary gland development ( 0.0084148872458365 ); ----------------KEGG-------------- hsa00330 Arginine and proline metabolism ( 0.0209155700491858 ); hsa05110 Vibrio cholerae infection ( 0.0344409223443456 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.036775598045415 ); hsa04640 Hematopoietic cell lineage ( 0.049524077173405 ); ----------------CARTA-------------- ( 0.00961170087218188 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3270 ========================= ----------------C2-------------- ( 0.00961170087218188 ); ----------------C3-------------- ( ); ----------------C4-------------- GCM_SMARCD1 ( 0.00162958511145743 ); GCM_HMGA2 ( 0.00228938688209095 ); module_65 ( 0.00601728183317862 ); module_454 ( 0.00601728183317862 ); module_335 ( 0.0084148872458365 ); module_445 ( 0.00901345967669531 ); ----------------C5-------------- CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.00232708419311333 ); SENSORY_PERCEPTION ( 0.00562371163146519 ); CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00601728183317862 ); HEME_BIOSYNTHETIC_PROCESS ( 0.00601728183317862 ); PHOSPHORUS_OXYGEN_LYASE_ACTIVITY ( 0.00601728183317862 ); HEME_METABOLIC_PROCESS ( 0.00661718087346452 ); CYCLASE_ACTIVITY ( 0.00661718087346452 ); CYTOCHROME_C_OXIDASE_ACTIVITY ( 0.00781598341288636 ); ----------------GOSLIM-------------- GO:0008495 protoheme IX farnesyltransferase activity ( ); GO:0006123 mitochondrial electron transport, cytochrome c to oxygen ( ); GO:0006784 heme a biosynthetic process ( ); GO:0017004 cytochrome complex assembly ( ); GO:0046160 heme a metabolic process ( ); GO:0009190 cyclic nucleotide biosynthetic process ( ); GO:0009187 cyclic nucleotide metabolic process ( ); GO:0000266 mitochondrial fission ( ); GO:0004311 farnesyltranstransferase activity ( ); GO:0001609 adenosine receptor activity, G-protein coupled ( ); GO:0007168 receptor guanylyl cyclase signaling pathway ( ); GO:0008535 respiratory chain complex IV assembly ( ); GO:0004383 guanylate cyclase activity ( ); GO:0006182 cGMP biosynthetic process ( ); GO:0004659 prenyltransferase activity ( ); GO:0006783 heme biosynthetic process ( ); GO:0046068 cGMP metabolic process ( ); GO:0009165 nucleotide biosynthetic process ( ); GO:0007600 sensory perception ( ); GO:0016310 phosphorylation ( ); ----------------GO-------------- GO:0008495 protoheme IX farnesyltransferase activity ( 0.000603227265872364 ); GO:0006123 mitochondrial electron transport, cytochrome c to oxygen ( 0.0012061209554366 ); GO:0006784 heme a biosynthetic process ( 0.0012061209554366 ); GO:0017004 cytochrome complex assembly ( 0.0012061209554366 ); GO:0046160 heme a metabolic process ( 0.0012061209554366 ); GO:0009190 cyclic nucleotide biosynthetic process ( 0.00147393423584277 ); GO:0009187 cyclic nucleotide metabolic process ( 0.00166161997068105 ); GO:0000266 mitochondrial fission ( 0.0024109082763728 ); GO:0004311 farnesyltranstransferase activity ( 0.0024109082763728 ); GO:0001609 adenosine receptor activity, G-protein coupled ( 0.00301280224292078 ); GO:0007168 receptor guanylyl cyclase signaling pathway ( 0.0036143633035145 ); GO:0008535 respiratory chain complex IV assembly ( 0.00481648737635654 ); GO:0004383 guanylate cyclase activity ( 0.00481648737635654 ); GO:0006182 cGMP biosynthetic process ( 0.0084148872458365 ); GO:0004659 prenyltransferase activity ( 0.0084148872458365 ); GO:0006783 heme biosynthetic process ( 0.00901345967669531 ); GO:0046068 cGMP metabolic process ( 0.00901345967669531 ); GO:0009165 nucleotide biosynthetic process ( 0.00948153503297737 ); GO:0007600 sensory perception ( 0.00960775738972064 ); GO:0016310 phosphorylation ( 0.00964221940618702 ); ----------------KEGG-------------- hsa00860 Porphyrin and chlorophyll metabolism ( 0.0197312833679226 ); hsa04730 Long-term depression ( 0.0437486123651611 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0102096109989385 ); ============================ group2720 ========================= ----------------C2-------------- KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION ( 0.000923130686742811 ); KEGG_OOCYTE_MEIOSIS ( 0.00161306894683454 ); REACTOME_INTEGRATION_OF_ENERGY_METABOLISM ( 0.00594294837155327 ); REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY ( 0.00606727341986968 ); REACTOME_MTORC1_MEDIATED_SIGNALLING ( 0.00606727341986968 ); REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION ( 0.00661718087346486 ); REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING ( 0.00716681172756606 ); REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS ( 0.00771616610739501 ); BIOCARTA_EIF_PATHWAY ( 0.00881404594486701 ); REACTOME_PHOSPHORYLATION_OF_THE_APC ( 0.00881404594486701 ); KEGG_PHENYLALANINE_METABOLISM ( 0.00936257165270038 ); REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B ( 0.00936257165270038 ); REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE ( 0.00936257165270038 ); REACTOME_PKA_ACTIVATION ( 0.00936257165270038 ); REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX ( 0.00991082138664212 ); ----------------C3-------------- V$DR1_Q3 ( 0.0040170306485539 ); V$PR_Q2 ( 0.00471593838608716 ); V$NMYC_01 ( 0.00516050165556377 ); V$GR_Q6 ( 0.00546728419130017 ); V$USF_C ( 0.00567640301830587 ); CGCTGCT,MIR-503 ( 0.00991082138664212 ); ----------------C4-------------- MORF_EI24 ( 4.95423080913704e-05 ); MORF_BUB1 ( 0.000335630173457464 ); MORF_ESPL1 ( 0.000451803504033351 ); MORF_RRM1 ( 0.00110817153995601 ); MORF_DNMT1 ( 0.00149917724486118 ); module_152 ( 0.00191536605710393 ); MORF_RFC4 ( 0.00252211540654903 ); MORF_PPP1CC ( 0.00304895942700519 ); MORF_HAT1 ( 0.00320821419480888 ); MORF_PRKDC ( 0.0038836084351466 ); MORF_HDAC2 ( 0.00834087248099378 ); MORF_CSNK2B ( 0.00853095059952927 ); MORF_BUB3 ( 0.0085947465173343 ); module_414 ( 0.00936257165270038 ); MORF_GNB1 ( 0.00991614215677779 ); ----------------C5-------------- INTEGRATOR_COMPLEX ( 0.00716681172756606 ); PROTEIN_COMPLEX ( 0.00824770857848503 ); PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX ( 0.00826524413812202 ); ----------------GOSLIM-------------- GO:0006532 aspartate biosynthetic process ( 0.00788735995371513 ); GO:0019550 glutamate catabolic process to aspartate ( 0.00788735995371513 ); GO:0019551 glutamate catabolic process to 2-oxoglutarate ( 0.00788735995371513 ); GO:0042776 mitochondrial ATP synthesis coupled proton transport ( 0.00788735995371513 ); GO:0006106 fumarate metabolic process ( 0.00788735995371513 ); GO:0004069 aspartate transaminase activity ( 0.00788735995371513 ); GO:0004768 stearoyl-CoA 9-desaturase activity ( 0.00788735995371513 ); GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity ( 0.00788735995371513 ); GO:0006531 aspartate metabolic process ( 0.00788735995371513 ); GO:0006533 aspartate catabolic process ( 0.00788735995371513 ); GO:0006103 2-oxoglutarate metabolic process ( 0.00788735995371513 ); GO:0006538 glutamate catabolic process ( 0.00788735995371513 ); GO:0007143 female meiosis ( 0.00788735995371513 ); GO:0009068 aspartate family amino acid catabolic process ( 0.00788735995371513 ); GO:0042180 cellular ketone metabolic process ( 0.00788735995371513 ); GO:0006200 ATP catabolic process ( 0.00788735995371513 ); GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ( 0.00788735995371513 ); GO:0006107 oxaloacetate metabolic process ( 0.00788735995371513 ); GO:0009203 ribonucleoside triphosphate catabolic process ( 0.00788735995371513 ); GO:0009207 purine ribonucleoside triphosphate catabolic process ( 0.00788735995371513 ); GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) ( 0.00788735995371513 ); GO:0009146 purine nucleoside triphosphate catabolic process ( 0.00788735995371513 ); GO:0016281 eukaryotic translation initiation factor 4F complex ( 0.00788735995371513 ); GO:0009154 purine ribonucleotide catabolic process ( 0.00788735995371513 ); GO:0016073 snRNA metabolic process ( 0.00788735995371513 ); GO:0016180 snRNA processing ( 0.00788735995371513 ); GO:0004016 adenylate cyclase activity ( 0.00788735995371513 ); GO:0009143 nucleoside triphosphate catabolic process ( 0.00788735995371513 ); GO:0009261 ribonucleotide catabolic process ( 0.00788735995371513 ); GO:0015908 fatty acid transport ( 0.00788735995371513 ); GO:0032039 integrator complex ( 0.00788735995371513 ); GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism ( 0.00788735995371513 ); GO:0006195 purine nucleotide catabolic process ( 0.00788735995371513 ); GO:0009165 nucleotide biosynthetic process ( 0.00788735995371513 ); GO:0005743 mitochondrial inner membrane ( 0.00788735995371513 ); GO:0006536 glutamate metabolic process ( 0.00788735995371513 ); GO:0009067 aspartate family amino acid biosynthetic process ( 0.00788735995371513 ); GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain ( 0.00788735995371513 ); GO:0019866 organelle inner membrane ( 0.00788735995371513 ); GO:0009065 glutamine family amino acid catabolic process ( 0.00788735995371513 ); GO:0005753 mitochondrial proton-transporting ATP synthase complex ( 0.00788735995371513 ); ----------------GO-------------- GO:0006532 aspartate biosynthetic process ( 0.00110563867384261 ); GO:0019550 glutamate catabolic process to aspartate ( 0.00110563867384261 ); GO:0019551 glutamate catabolic process to 2-oxoglutarate ( 0.00110563867384261 ); GO:0042776 mitochondrial ATP synthesis coupled proton transport ( 0.00110563867384261 ); GO:0006106 fumarate metabolic process ( 0.00165804116615509 ); GO:0004069 aspartate transaminase activity ( 0.00165804116615509 ); GO:0004768 stearoyl-CoA 9-desaturase activity ( 0.00165804116615509 ); GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity ( 0.00165804116615509 ); GO:0006531 aspartate metabolic process ( 0.00221016592971301 ); GO:0006533 aspartate catabolic process ( 0.00221016592971301 ); GO:0006103 2-oxoglutarate metabolic process ( 0.00276201309019242 ); GO:0006538 glutamate catabolic process ( 0.00276201309019242 ); GO:0007143 female meiosis ( 0.00276201309019242 ); GO:0009068 aspartate family amino acid catabolic process ( 0.00276201309019242 ); GO:0042180 cellular ketone metabolic process ( 0.00276201309019242 ); GO:0006200 ATP catabolic process ( 0.00331358277321803 ); GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ( 0.00331358277321803 ); GO:0006107 oxaloacetate metabolic process ( 0.00386487510436395 ); GO:0009203 ribonucleoside triphosphate catabolic process ( 0.00386487510436395 ); GO:0009207 purine ribonucleoside triphosphate catabolic process ( 0.00386487510436395 ); GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) ( 0.00386487510436395 ); GO:0009146 purine nucleoside triphosphate catabolic process ( 0.00441589020915334 ); GO:0016281 eukaryotic translation initiation factor 4F complex ( 0.00441589020915334 ); GO:0009154 purine ribonucleotide catabolic process ( 0.00496662821306104 ); GO:0016073 snRNA metabolic process ( 0.00551708924150907 ); GO:0016180 snRNA processing ( 0.00551708924150907 ); GO:0004016 adenylate cyclase activity ( 0.00551708924150907 ); GO:0009143 nucleoside triphosphate catabolic process ( 0.00606727341986968 ); GO:0009261 ribonucleotide catabolic process ( 0.00606727341986968 ); GO:0015908 fatty acid transport ( 0.00606727341986968 ); GO:0032039 integrator complex ( 0.00606727341986968 ); GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism ( 0.00661718087346486 ); GO:0006195 purine nucleotide catabolic process ( 0.00716681172756606 ); GO:0009165 nucleotide biosynthetic process ( 0.00796662897386954 ); GO:0005743 mitochondrial inner membrane ( 0.00802845397967281 ); GO:0006536 glutamate metabolic process ( 0.00826524413812202 ); GO:0009067 aspartate family amino acid biosynthetic process ( 0.00826524413812202 ); GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain ( 0.00936257165270038 ); GO:0019866 organelle inner membrane ( 0.00944384564278453 ); GO:0009065 glutamine family amino acid catabolic process ( 0.00991082138664212 ); GO:0005753 mitochondrial proton-transporting ATP synthase complex ( 0.00991082138664212 ); ----------------KEGG-------------- hsa00950 Alkaloid biosynthesis I ( 0.00276201309019242 ); hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis ( 0.00496662821306104 ); hsa00272 Cysteine metabolism ( 0.00716681172756606 ); hsa00360 Phenylalanine metabolism ( 0.0110064934326759 ); hsa01040 Biosynthesis of unsaturated fatty acids ( 0.0115539159945554 ); hsa00251 Glutamate metabolism ( 0.0131945313333189 ); hsa00252 Alanine and aspartate metabolism ( 0.0153781676303555 ); hsa00330 Arginine and proline metabolism ( 0.0191889637586496 ); hsa00350 Tyrosine metabolism ( 0.0246097015170407 ); hsa05110 Vibrio cholerae infection ( 0.0316159411849419 ); hsa03320 PPAR signaling pathway ( 0.0369741896203146 ); ----------------CARTA-------------- irespathway ( 0.00165804116615509 ); mcmpathway ( 0.00221016592971301 ); ionpathway ( 0.00441589020915334 ); hivnefpathway ( 0.016468337668869 ); il2rbpathway ( 0.0229863470029374 ); ----------------RBP-------------- AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000155517471502619 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.000767086758554701 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.000940804057906192 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00125664785721146 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0185811977978258 ); TIA1_iCLIP_(Wang_2010) ( 0.0198669942080915 ); TIAL1_iCLIP_(Wang_2010) ( 0.0212827642565239 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0273456646159053 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0284203197072275 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2742 ========================= ----------------C2-------------- KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES ( 0.00771616610739501 ); REACTOME_OTHER_SEMAPHORIN_INTERACTIONS ( 0.00826524413812202 ); ----------------C3-------------- V$EVI1_02 ( 0.00118179143130602 ); ACCTGTTG_UNKNOWN ( 0.00173098368295613 ); V$GATA_Q6 ( 0.00328928704389123 ); V$LFA1_Q6 ( 0.00447710529677059 ); V$GATA1_03 ( 0.00457193757097226 ); V$GATA1_04 ( 0.00461970441335757 ); V$LMO2COM_02 ( 0.00481310458090311 ); V$PAX4_01 ( 0.00516050165556377 ); V$EVI1_01 ( 0.00661718087346486 ); GCGCCTT,MIR-525,MIR-524 ( 0.00661718087346486 ); V$AHRARNT_02 ( 0.00716681172756606 ); ----------------C4-------------- ( ); ----------------C5-------------- NEUROTRANSMITTER_SECRETION ( 0.00716681172756606 ); REGULATED_SECRETORY_PATHWAY ( 0.00826524413812202 ); GALACTOSYLTRANSFERASE_ACTIVITY ( 0.00826524413812202 ); ----------------GOSLIM-------------- GO:0015819 lysine transport ( 0.00865876034947672 ); GO:0021557 oculomotor nerve development ( 0.00865876034947672 ); GO:0021558 trochlear nerve development ( 0.00865876034947672 ); GO:0005618 cell wall ( 0.00865876034947672 ); GO:0009505 plant-type cell wall ( 0.00865876034947672 ); GO:0009530 primary cell wall ( 0.00865876034947672 ); GO:0044426 cell wall part ( 0.00865876034947672 ); GO:0048196 middle lamella-containing extracellular matrix ( 0.00865876034947672 ); GO:0048222 glycoprotein network ( 0.00865876034947672 ); GO:0015189 L-lysine transmembrane transporter activity ( 0.00865876034947672 ); GO:0015326 cationic amino acid transmembrane transporter activity ( 0.00865876034947672 ); GO:0050512 lactosylceramide 4-alpha-galactosyltransferase activity ( 0.00865876034947672 ); GO:0021555 midbrain-hindbrain boundary morphogenesis ( 0.00865876034947672 ); GO:0045608 negative regulation of auditory receptor cell differentiation ( 0.00865876034947672 ); GO:0045632 negative regulation of mechanoreceptor differentiation ( 0.00865876034947672 ); GO:0060164 regulation of timing of neuron differentiation ( 0.00865876034947672 ); GO:0044462 external encapsulating structure part ( 0.00865876034947672 ); GO:0015181 arginine transmembrane transporter activity ( 0.00865876034947672 ); GO:0015809 arginine transport ( 0.00865876034947672 ); GO:0042668 auditory receptor cell fate determination ( 0.00865876034947672 ); GO:0045607 regulation of auditory receptor cell differentiation ( 0.00865876034947672 ); GO:0045631 regulation of mechanoreceptor differentiation ( 0.00865876034947672 ); GO:0030312 external encapsulating structure ( 0.00865876034947672 ); GO:0004687 myosin light chain kinase activity ( 0.00865876034947672 ); GO:0009912 auditory receptor cell fate commitment ( 0.00865876034947672 ); GO:0021783 preganglionic parasympathetic nervous system development ( 0.00865876034947672 ); GO:0021903 rostrocaudal neural tube patterning ( 0.00865876034947672 ); GO:0030917 midbrain-hindbrain boundary development ( 0.00865876034947672 ); GO:0040034 regulation of development, heterochronic ( 0.00865876034947672 ); GO:0048505 regulation of timing of cell differentiation ( 0.00865876034947672 ); GO:0060120 inner ear receptor cell fate commitment ( 0.00865876034947672 ); GO:0015802 basic amino acid transport ( 0.00865876034947672 ); GO:0048486 parasympathetic nervous system development ( 0.00865876034947672 ); GO:0048664 neuron fate determination ( 0.00865876034947672 ); GO:0004969 histamine receptor activity ( 0.00865876034947672 ); GO:0015174 basic amino acid transmembrane transporter activity ( 0.00865876034947672 ); GO:0006688 glycosphingolipid biosynthetic process ( 0.00865876034947672 ); GO:0021532 neural tube patterning ( 0.00865876034947672 ); GO:0042491 auditory receptor cell differentiation ( 0.00865876034947672 ); GO:0030901 midbrain development ( 0.00865876034947672 ); GO:0051291 protein heterooligomerization ( 0.00865876034947672 ); GO:0048483 autonomic nervous system development ( 0.00865876034947672 ); GO:0060113 inner ear receptor cell differentiation ( 0.00865876034947672 ); GO:0021575 hindbrain morphogenesis ( 0.00865876034947672 ); GO:0007009 plasma membrane organization ( 0.00865876034947672 ); GO:0009247 glycolipid biosynthetic process ( 0.00865876034947672 ); GO:0021545 cranial nerve development ( 0.00865876034947672 ); GO:0021983 pituitary gland development ( 0.00865876034947672 ); GO:0042490 mechanoreceptor differentiation ( 0.00865876034947672 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00865876034947672 ); GO:0006687 glycosphingolipid metabolic process ( 0.00865876034947672 ); ----------------GO-------------- GO:0015819 lysine transport ( 0.000552958327049713 ); GO:0021557 oculomotor nerve development ( 0.000552958327049713 ); GO:0021558 trochlear nerve development ( 0.000552958327049713 ); GO:0005618 cell wall ( 0.000552958327049713 ); GO:0009505 plant-type cell wall ( 0.000552958327049713 ); GO:0009530 primary cell wall ( 0.000552958327049713 ); GO:0044426 cell wall part ( 0.000552958327049713 ); GO:0048196 middle lamella-containing extracellular matrix ( 0.000552958327049713 ); GO:0048222 glycoprotein network ( 0.000552958327049713 ); GO:0015189 L-lysine transmembrane transporter activity ( 0.000552958327049713 ); GO:0015326 cationic amino acid transmembrane transporter activity ( 0.000552958327049713 ); GO:0050512 lactosylceramide 4-alpha-galactosyltransferase activity ( 0.000552958327049713 ); GO:0021555 midbrain-hindbrain boundary morphogenesis ( 0.00110563867384261 ); GO:0045608 negative regulation of auditory receptor cell differentiation ( 0.00110563867384261 ); GO:0045632 negative regulation of mechanoreceptor differentiation ( 0.00110563867384261 ); GO:0060164 regulation of timing of neuron differentiation ( 0.00110563867384261 ); GO:0044462 external encapsulating structure part ( 0.00110563867384261 ); GO:0015181 arginine transmembrane transporter activity ( 0.00110563867384261 ); GO:0015809 arginine transport ( 0.00165804116615509 ); GO:0042668 auditory receptor cell fate determination ( 0.00165804116615509 ); GO:0045607 regulation of auditory receptor cell differentiation ( 0.00165804116615509 ); GO:0045631 regulation of mechanoreceptor differentiation ( 0.00165804116615509 ); GO:0030312 external encapsulating structure ( 0.00165804116615509 ); GO:0004687 myosin light chain kinase activity ( 0.00165804116615509 ); GO:0009912 auditory receptor cell fate commitment ( 0.00221016592971301 ); GO:0021783 preganglionic parasympathetic nervous system development ( 0.00221016592971301 ); GO:0021903 rostrocaudal neural tube patterning ( 0.00221016592971301 ); GO:0030917 midbrain-hindbrain boundary development ( 0.00221016592971301 ); GO:0040034 regulation of development, heterochronic ( 0.00221016592971301 ); GO:0048505 regulation of timing of cell differentiation ( 0.00221016592971301 ); GO:0060120 inner ear receptor cell fate commitment ( 0.00221016592971301 ); GO:0015802 basic amino acid transport ( 0.00276201309019242 ); GO:0048486 parasympathetic nervous system development ( 0.00276201309019242 ); GO:0048664 neuron fate determination ( 0.00276201309019242 ); GO:0004969 histamine receptor activity ( 0.00331358277321803 ); GO:0015174 basic amino acid transmembrane transporter activity ( 0.00386487510436395 ); GO:0006688 glycosphingolipid biosynthetic process ( 0.00496662821306104 ); GO:0021532 neural tube patterning ( 0.00496662821306104 ); GO:0042491 auditory receptor cell differentiation ( 0.00496662821306104 ); GO:0030901 midbrain development ( 0.00551708924150907 ); GO:0051291 protein heterooligomerization ( 0.00551708924150907 ); GO:0048483 autonomic nervous system development ( 0.00606727341986968 ); GO:0060113 inner ear receptor cell differentiation ( 0.00606727341986968 ); GO:0021575 hindbrain morphogenesis ( 0.00661718087346486 ); GO:0007009 plasma membrane organization ( 0.00771616610739501 ); GO:0009247 glycolipid biosynthetic process ( 0.00771616610739501 ); GO:0021545 cranial nerve development ( 0.00771616610739501 ); GO:0021983 pituitary gland development ( 0.00771616610739501 ); GO:0042490 mechanoreceptor differentiation ( 0.00771616610739501 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00881404594486701 ); GO:0006687 glycosphingolipid metabolic process ( 0.00991082138664212 ); ----------------KEGG-------------- hsa00603 Glycosphingolipid biosynthesis - globo series ( 0.00771616610739501 ); hsa04950 Maturity onset diabetes of the young ( 0.0126479348201337 ); hsa04330 Notch signaling pathway ( 0.0246097015170407 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0342984438676286 ); ----------------CARTA-------------- ( 0.0148326707703162 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2763 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$FOXO3_01 ( 0.000104835060039267 ); V$NKX25_01 ( 0.00120684216412528 ); YTAATTAA_V$LHX3_01 ( 0.00274206500476837 ); V$SRY_01 ( 0.00277957692196941 ); TAATTA_V$CHX10_01 ( 0.00391996600436481 ); V$FOXO1_02 ( 0.00406197788904367 ); V$AREB6_03 ( 0.00415258076667528 ); V$PPAR_DR1_Q2 ( 0.00443004031441539 ); V$FOXO4_02 ( 0.00466770475985687 ); V$NFKAPPAB_01 ( 0.00471593838608716 ); V$HNF4_01 ( 0.00486203670141703 ); V$AP3_Q6 ( 0.00496059786951776 ); V$HNF4ALPHA_Q6 ( 0.00521105576856506 ); V$NFKB_C ( 0.00546728419130017 ); AACTTT_UNKNOWN ( 0.00578010179443095 ); CTTTGT_V$LEF1_Q2 ( 0.00607556818574252 ); TTGTTT_V$FOXO4_01 ( 0.00681033772112935 ); ----------------C4-------------- ( ); ----------------C5-------------- LIGAND_GATED_CHANNEL_ACTIVITY ( 0.000203696867752095 ); METAL_ION_TRANSPORT ( 0.0017914449832191 ); CATION_CHANNEL_ACTIVITY ( 0.00182205079430702 ); GATED_CHANNEL_ACTIVITY ( 0.00194696964030431 ); METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00274206500476837 ); CATION_TRANSPORT ( 0.00277957692196941 ); ION_CHANNEL_ACTIVITY ( 0.00281733212410539 ); SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY ( 0.00308841117988541 ); ION_TRANSPORT ( 0.00438320973509662 ); CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00572925533215594 ); VITAMIN_METABOLIC_PROCESS ( 0.00936257165270038 ); SODIUM_CHANNEL_ACTIVITY ( 0.00936257165270038 ); ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.0095777150259179 ); ----------------GOSLIM-------------- GO:0004991 parathyroid hormone receptor activity ( ); GO:0030001 metal ion transport ( ); GO:0015276 ligand-gated ion channel activity ( ); GO:0022834 ligand-gated channel activity ( ); GO:0006812 cation transport ( ); GO:0008266 poly(U) binding ( ); GO:0015279 store-operated calcium channel activity ( ); GO:0030005 cellular di-, tri-valent inorganic cation homeostasis ( ); GO:0015674 di-, tri-valent inorganic cation transport ( ); GO:0055066 di-, tri-valent inorganic cation homeostasis ( ); GO:0015280 amiloride-sensitive sodium channel activity ( ); GO:0030003 cellular cation homeostasis ( ); GO:0002076 osteoblast development ( ); GO:0008143 poly(A) binding ( ); GO:0008199 ferric iron binding ( ); GO:0055080 cation homeostasis ( ); GO:0031526 brush border membrane ( ); GO:0006811 ion transport ( ); GO:0019904 protein domain specific binding ( ); GO:0016918 retinal binding ( ); GO:0019841 retinol binding ( ); GO:0002062 chondrocyte differentiation ( ); GO:0050699 WW domain binding ( ); GO:0005261 cation channel activity ( ); GO:0042169 SH2 domain binding ( ); GO:0006873 cellular ion homeostasis ( ); GO:0005506 iron ion binding ( ); GO:0055082 cellular chemical homeostasis ( ); GO:0045453 bone resorption ( ); ----------------GO-------------- GO:0004991 parathyroid hormone receptor activity ( 0.00110563867384261 ); GO:0030001 metal ion transport ( 0.00160482564526209 ); GO:0015276 ligand-gated ion channel activity ( 0.00182205079430702 ); GO:0022834 ligand-gated channel activity ( 0.00182205079430702 ); GO:0006812 cation transport ( 0.00247797261236755 ); GO:0008266 poly(U) binding ( 0.00276201309019242 ); GO:0015279 store-operated calcium channel activity ( 0.00331358277321803 ); GO:0030005 cellular di-, tri-valent inorganic cation homeostasis ( 0.00341269800036019 ); GO:0015674 di-, tri-valent inorganic cation transport ( 0.00362317219308067 ); GO:0055066 di-, tri-valent inorganic cation homeostasis ( 0.00370903279505415 ); GO:0015280 amiloride-sensitive sodium channel activity ( 0.00386487510436395 ); GO:0030003 cellular cation homeostasis ( 0.00429025268602184 ); GO:0002076 osteoblast development ( 0.00441589020915334 ); GO:0008143 poly(A) binding ( 0.00441589020915334 ); GO:0008199 ferric iron binding ( 0.00441589020915334 ); GO:0055080 cation homeostasis ( 0.00546728419130017 ); GO:0031526 brush border membrane ( 0.00551708924150907 ); GO:0006811 ion transport ( 0.00607453343285486 ); GO:0019904 protein domain specific binding ( 0.00610560993440653 ); GO:0016918 retinal binding ( 0.00661718087346486 ); GO:0019841 retinol binding ( 0.00661718087346486 ); GO:0002062 chondrocyte differentiation ( 0.00716681172756606 ); GO:0050699 WW domain binding ( 0.00716681172756606 ); GO:0005261 cation channel activity ( 0.00760030794965364 ); GO:0042169 SH2 domain binding ( 0.00881404594486701 ); GO:0006873 cellular ion homeostasis ( 0.00898209071600656 ); GO:0005506 iron ion binding ( 0.00924465560535374 ); GO:0055082 cellular chemical homeostasis ( 0.0093108367953807 ); GO:0045453 bone resorption ( 0.00936257165270038 ); ----------------KEGG-------------- ( 0.026770359866658 ); ----------------CARTA-------------- ( 0.00661718087346486 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2765 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_360 ( 0.00716681172756606 ); module_464 ( 0.00771616610739501 ); module_194 ( 0.00826524413812202 ); ----------------C5-------------- LIGASE_ACTIVITY ( 0.0012577083566589 ); COENZYME_BIOSYNTHETIC_PROCESS ( 0.00551708924150907 ); LIGASE_ACTIVITY__FORMING_CARBON_OXYGEN_BONDS ( 0.00771616610739501 ); TRNA_METABOLIC_PROCESS ( 0.00991082138664212 ); OXYGEN_AND_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS ( 0.00991082138664212 ); ----------------GOSLIM-------------- GO:0006431 methionyl-tRNA aminoacylation ( ); GO:0019008 molybdopterin synthase complex ( ); GO:0004031 aldehyde oxidase activity ( ); GO:0004825 methionine-tRNA ligase activity ( ); GO:0004854 xanthine dehydrogenase activity ( ); GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor ( ); GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor ( ); GO:0021692 cerebellar Purkinje cell layer morphogenesis ( ); GO:0021694 cerebellar Purkinje cell layer formation ( ); GO:0021702 cerebellar Purkinje cell differentiation ( ); GO:0021937 Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation ( ); GO:0006777 Mo-molybdopterin cofactor biosynthetic process ( ); GO:0019720 Mo-molybdopterin cofactor metabolic process ( ); GO:0032324 molybdopterin cofactor biosynthetic process ( ); GO:0043545 molybdopterin cofactor metabolic process ( ); GO:0016725 oxidoreductase activity, acting on CH or CH2 groups ( ); GO:0021680 cerebellar Purkinje cell layer development ( ); GO:0021697 cerebellar cortex formation ( ); GO:0021936 regulation of granule cell precursor proliferation ( ); GO:0021940 positive regulation of granule cell precursor proliferation ( ); GO:0030151 molybdenum ion binding ( ); GO:0021533 cell differentiation in hindbrain ( ); GO:0021534 cell proliferation in hindbrain ( ); GO:0021924 cell proliferation in the external granule layer ( ); GO:0021930 granule cell precursor proliferation ( ); GO:0021696 cerebellar cortex morphogenesis ( ); GO:0021587 cerebellum morphogenesis ( ); GO:0021575 hindbrain morphogenesis ( ); GO:0021695 cerebellar cortex development ( ); GO:0042559 pteridine and derivative biosynthetic process ( ); GO:0019438 aromatic compound biosynthetic process ( ); GO:0042558 pteridine and derivative metabolic process ( ); GO:0006309 DNA fragmentation during apoptosis ( ); GO:0021549 cerebellum development ( ); GO:0051537 2 iron, 2 sulfur cluster binding ( ); ----------------GO-------------- GO:0006431 methionyl-tRNA aminoacylation ( 0.00110563867384261 ); GO:0019008 molybdopterin synthase complex ( 0.00110563867384261 ); GO:0004031 aldehyde oxidase activity ( 0.00110563867384261 ); GO:0004825 methionine-tRNA ligase activity ( 0.00110563867384261 ); GO:0004854 xanthine dehydrogenase activity ( 0.00110563867384261 ); GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor ( 0.00110563867384261 ); GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor ( 0.00110563867384261 ); GO:0021692 cerebellar Purkinje cell layer morphogenesis ( 0.00221016592971301 ); GO:0021694 cerebellar Purkinje cell layer formation ( 0.00221016592971301 ); GO:0021702 cerebellar Purkinje cell differentiation ( 0.00221016592971301 ); GO:0021937 Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation ( 0.00221016592971301 ); GO:0006777 Mo-molybdopterin cofactor biosynthetic process ( 0.00331358277321803 ); GO:0019720 Mo-molybdopterin cofactor metabolic process ( 0.00331358277321803 ); GO:0032324 molybdopterin cofactor biosynthetic process ( 0.00331358277321803 ); GO:0043545 molybdopterin cofactor metabolic process ( 0.00331358277321803 ); GO:0016725 oxidoreductase activity, acting on CH or CH2 groups ( 0.00331358277321803 ); GO:0021680 cerebellar Purkinje cell layer development ( 0.00386487510436395 ); GO:0021697 cerebellar cortex formation ( 0.00386487510436395 ); GO:0021936 regulation of granule cell precursor proliferation ( 0.00386487510436395 ); GO:0021940 positive regulation of granule cell precursor proliferation ( 0.00386487510436395 ); GO:0030151 molybdenum ion binding ( 0.00386487510436395 ); GO:0021533 cell differentiation in hindbrain ( 0.00441589020915334 ); GO:0021534 cell proliferation in hindbrain ( 0.00441589020915334 ); GO:0021924 cell proliferation in the external granule layer ( 0.00441589020915334 ); GO:0021930 granule cell precursor proliferation ( 0.00441589020915334 ); GO:0021696 cerebellar cortex morphogenesis ( 0.00496662821306104 ); GO:0021587 cerebellum morphogenesis ( 0.00606727341986968 ); GO:0021575 hindbrain morphogenesis ( 0.00661718087346486 ); GO:0021695 cerebellar cortex development ( 0.00661718087346486 ); GO:0042559 pteridine and derivative biosynthetic process ( 0.00661718087346486 ); GO:0019438 aromatic compound biosynthetic process ( 0.00716681172756606 ); GO:0042558 pteridine and derivative metabolic process ( 0.00826524413812202 ); GO:0006309 DNA fragmentation during apoptosis ( 0.00881404594486701 ); GO:0021549 cerebellum development ( 0.00881404594486701 ); GO:0051537 2 iron, 2 sulfur cluster binding ( 0.00881404594486701 ); ----------------KEGG-------------- hsa00750 Vitamin B6 metabolism ( 0.00276201309019242 ); hsa00271 Methionine metabolism ( 0.0115539159945554 ); hsa00760 Nicotinate and nicotinamide metabolism ( 0.0131945313333189 ); hsa00450 Selenoamino acid metabolism ( 0.0137408527463404 ); hsa00970 Aminoacyl-tRNA biosynthesis ( 0.0224446832670893 ); hsa00350 Tyrosine metabolism ( 0.0246097015170407 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0251502745361519 ); hsa00380 Tryptophan metabolism ( 0.027309844146111 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0348341330818219 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2766 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$SRY_01 ( 0.00277957692196941 ); V$AREB6_01 ( 0.00501022646986489 ); ----------------C4-------------- ( 0.00124130082967278 ); ----------------C5-------------- POSITIVE_REGULATION_OF_CYTOKINE_SECRETION ( 0.00496662821306104 ); POSITIVE_REGULATION_OF_DEFENSE_RESPONSE ( 0.00551708924150907 ); DETECTION_OF_BIOTIC_STIMULUS ( 0.00551708924150907 ); POSITIVE_REGULATION_OF_PROTEIN_SECRETION ( 0.00606727341986968 ); REGULATION_OF_CYTOKINE_SECRETION ( 0.00826524413812202 ); REGULATION_OF_IMMUNE_EFFECTOR_PROCESS ( 0.00826524413812202 ); CYTOKINE_SECRETION ( 0.00936257165270038 ); CELL_RECOGNITION ( 0.00991082138664212 ); ----------------GOSLIM-------------- GO:0030246 carbohydrate binding ( ); GO:0002355 detection of tumor cell ( ); GO:0005539 glycosaminoglycan binding ( ); GO:0030247 polysaccharide binding ( ); GO:0001871 pattern binding ( ); GO:0004252 serine-type endopeptidase activity ( ); GO:0001913 T cell mediated cytotoxicity ( ); GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target ( ); GO:0002423 natural killer cell mediated immune response to tumor cell ( ); GO:0002855 regulation of natural killer cell mediated immune response to tumor cell ( ); GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell ( ); GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target ( ); GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target ( ); GO:0008236 serine-type peptidase activity ( ); GO:0017171 serine hydrolase activity ( ); GO:0002833 positive regulation of response to biotic stimulus ( ); GO:0002834 regulation of response to tumor cell ( ); GO:0002836 positive regulation of response to tumor cell ( ); GO:0002837 regulation of immune response to tumor cell ( ); GO:0002839 positive regulation of immune response to tumor cell ( ); GO:0002418 immune response to tumor cell ( ); GO:0002717 positive regulation of natural killer cell mediated immunity ( ); GO:0045954 positive regulation of natural killer cell mediated cytotoxicity ( ); GO:0001912 positive regulation of leukocyte mediated cytotoxicity ( ); GO:0002347 response to tumor cell ( ); GO:0002715 regulation of natural killer cell mediated immunity ( ); GO:0042269 regulation of natural killer cell mediated cytotoxicity ( ); GO:0050798 activated T cell proliferation ( ); GO:0001910 regulation of leukocyte mediated cytotoxicity ( ); GO:0031343 positive regulation of cell killing ( ); GO:0009595 detection of biotic stimulus ( ); GO:0002228 natural killer cell mediated immunity ( ); GO:0002456 T cell mediated immunity ( ); GO:0031341 regulation of cell killing ( ); GO:0042267 natural killer cell mediated cytotoxicity ( ); GO:0050715 positive regulation of cytokine secretion ( ); ----------------GO-------------- GO:0030246 carbohydrate binding ( 0.000392940195839539 ); GO:0002355 detection of tumor cell ( 0.000552958327049713 ); GO:0005539 glycosaminoglycan binding ( 0.0013095926018128 ); GO:0030247 polysaccharide binding ( 0.00138932366728031 ); GO:0001871 pattern binding ( 0.00188401156559414 ); GO:0004252 serine-type endopeptidase activity ( 0.00266777194755698 ); GO:0001913 T cell mediated cytotoxicity ( 0.00276201309019242 ); GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target ( 0.00331358277321803 ); GO:0002423 natural killer cell mediated immune response to tumor cell ( 0.00331358277321803 ); GO:0002855 regulation of natural killer cell mediated immune response to tumor cell ( 0.00331358277321803 ); GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell ( 0.00331358277321803 ); GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target ( 0.00331358277321803 ); GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target ( 0.00331358277321803 ); GO:0008236 serine-type peptidase activity ( 0.00358059949209345 ); GO:0017171 serine hydrolase activity ( 0.00362317219308067 ); GO:0002833 positive regulation of response to biotic stimulus ( 0.00441589020915334 ); GO:0002834 regulation of response to tumor cell ( 0.00441589020915334 ); GO:0002836 positive regulation of response to tumor cell ( 0.00441589020915334 ); GO:0002837 regulation of immune response to tumor cell ( 0.00441589020915334 ); GO:0002839 positive regulation of immune response to tumor cell ( 0.00441589020915334 ); GO:0002418 immune response to tumor cell ( 0.00496662821306104 ); GO:0002717 positive regulation of natural killer cell mediated immunity ( 0.00606727341986968 ); GO:0045954 positive regulation of natural killer cell mediated cytotoxicity ( 0.00606727341986968 ); GO:0001912 positive regulation of leukocyte mediated cytotoxicity ( 0.00661718087346486 ); GO:0002347 response to tumor cell ( 0.00661718087346486 ); GO:0002715 regulation of natural killer cell mediated immunity ( 0.00661718087346486 ); GO:0042269 regulation of natural killer cell mediated cytotoxicity ( 0.00661718087346486 ); GO:0050798 activated T cell proliferation ( 0.00661718087346486 ); GO:0001910 regulation of leukocyte mediated cytotoxicity ( 0.00771616610739501 ); GO:0031343 positive regulation of cell killing ( 0.00771616610739501 ); GO:0009595 detection of biotic stimulus ( 0.00826524413812202 ); GO:0002228 natural killer cell mediated immunity ( 0.00936257165270038 ); GO:0002456 T cell mediated immunity ( 0.00936257165270038 ); GO:0031341 regulation of cell killing ( 0.00936257165270038 ); GO:0042267 natural killer cell mediated cytotoxicity ( 0.00936257165270038 ); GO:0050715 positive regulation of cytokine secretion ( 0.00936257165270038 ); ----------------KEGG-------------- hsa04512 ECM-receptor interaction ( 0.0449610383622608 ); hsa05222 Small cell lung cancer ( 0.0465511634536048 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.040176186946897 ); ----------------ARE-------------- ( ); ============================ group2937 ========================= ----------------C2-------------- ( ); ----------------C3-------------- GACAATC,MIR-219 ( 0.00207587021244941 ); SCGGAAGY_V$ELK1_02 ( 0.0078249071716526 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0006500 N-terminal protein palmitoylation ( ); GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation ( ); GO:0018318 protein amino acid palmitoylation ( ); GO:0031312 extrinsic to organelle membrane ( ); GO:0031315 extrinsic to mitochondrial outer membrane ( ); GO:0006498 N-terminal protein lipidation ( ); GO:0018198 peptidyl-cysteine modification ( ); GO:0018345 protein palmitoylation ( ); GO:0045932 negative regulation of muscle contraction ( ); GO:0005861 troponin complex ( ); GO:0018409 peptide or protein amino-terminal blocking ( ); GO:0003009 skeletal muscle contraction ( ); GO:0008180 signalosome ( ); GO:0031365 N-terminal protein amino acid modification ( ); GO:0005523 tropomyosin binding ( ); GO:0005865 striated muscle thin filament ( ); GO:0007026 negative regulation of microtubule depolymerization ( ); GO:0009746 response to hexose stimulus ( ); GO:0009749 response to glucose stimulus ( ); GO:0031114 regulation of microtubule depolymerization ( ); GO:0034284 response to monosaccharide stimulus ( ); GO:0050879 multicellular organismal movement ( ); GO:0050881 musculoskeletal movement ( ); GO:0007019 microtubule depolymerization ( ); GO:0031111 negative regulation of microtubule polymerization or depolymerization ( ); GO:0005801 cis-Golgi network ( ); GO:0043229 intracellular organelle ( ); GO:0043226 organelle ( ); GO:0009743 response to carbohydrate stimulus ( ); GO:0031110 regulation of microtubule polymerization or depolymerization ( ); ----------------GO-------------- GO:0006500 N-terminal protein palmitoylation ( 0.000552958327049713 ); GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation ( 0.000552958327049713 ); GO:0018318 protein amino acid palmitoylation ( 0.000552958327049713 ); GO:0031312 extrinsic to organelle membrane ( 0.000552958327049713 ); GO:0031315 extrinsic to mitochondrial outer membrane ( 0.000552958327049713 ); GO:0006498 N-terminal protein lipidation ( 0.00110563867384261 ); GO:0018198 peptidyl-cysteine modification ( 0.00165804116615509 ); GO:0018345 protein palmitoylation ( 0.00276201309019242 ); GO:0045932 negative regulation of muscle contraction ( 0.00331358277321803 ); GO:0005861 troponin complex ( 0.00386487510436395 ); GO:0018409 peptide or protein amino-terminal blocking ( 0.00441589020915334 ); GO:0003009 skeletal muscle contraction ( 0.00551708924150907 ); GO:0008180 signalosome ( 0.00551708924150907 ); GO:0031365 N-terminal protein amino acid modification ( 0.00606727341986968 ); GO:0005523 tropomyosin binding ( 0.00606727341986968 ); GO:0005865 striated muscle thin filament ( 0.00661718087346486 ); GO:0007026 negative regulation of microtubule depolymerization ( 0.00716681172756606 ); GO:0009746 response to hexose stimulus ( 0.00716681172756606 ); GO:0009749 response to glucose stimulus ( 0.00716681172756606 ); GO:0031114 regulation of microtubule depolymerization ( 0.00716681172756606 ); GO:0034284 response to monosaccharide stimulus ( 0.00716681172756606 ); GO:0050879 multicellular organismal movement ( 0.00716681172756606 ); GO:0050881 musculoskeletal movement ( 0.00716681172756606 ); GO:0007019 microtubule depolymerization ( 0.00771616610739501 ); GO:0031111 negative regulation of microtubule polymerization or depolymerization ( 0.00771616610739501 ); GO:0005801 cis-Golgi network ( 0.00771616610739501 ); GO:0043229 intracellular organelle ( 0.00780213380689005 ); GO:0043226 organelle ( 0.00782438320033526 ); GO:0009743 response to carbohydrate stimulus ( 0.00991082138664212 ); GO:0031110 regulation of microtubule polymerization or depolymerization ( 0.00991082138664212 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0284203197072275 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2971 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- HEME_BIOSYNTHETIC_PROCESS ( 0.00551708924150907 ); BETA_TUBULIN_BINDING ( 0.00551708924150907 ); HEME_METABOLIC_PROCESS ( 0.00606727341986968 ); SINGLE_STRANDED_RNA_BINDING ( 0.00661718087346486 ); CENTROSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00826524413812202 ); MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS ( 0.00881404594486701 ); MICROTUBULE_BASED_MOVEMENT ( 0.00881404594486701 ); PIGMENT_BIOSYNTHETIC_PROCESS ( 0.00936257165270038 ); ATP_DEPENDENT_RNA_HELICASE_ACTIVITY ( 0.00936257165270038 ); MITOCHONDRIAL_OUTER_MEMBRANE ( 0.00991082138664212 ); PIGMENT_METABOLIC_PROCESS ( 0.00991082138664212 ); RNA_DEPENDENT_ATPASE_ACTIVITY ( 0.00991082138664212 ); ----------------GOSLIM-------------- GO:0015853 adenine transport ( ); GO:0019718 rough microsome ( ); GO:0006863 purine transport ( ); GO:0015851 nucleobase transport ( ); GO:0034643 mitochondrion localization, microtubule-mediated ( ); GO:0047497 mitochondrion transport along microtubule ( ); GO:0051654 establishment of mitochondrion localization ( ); GO:0008143 poly(A) binding ( ); GO:0016805 dipeptidase activity ( ); GO:0048487 beta-tubulin binding ( ); GO:0001662 behavioral fear response ( ); GO:0002209 behavioral defense response ( ); GO:0051646 mitochondrion localization ( ); GO:0000930 gamma-tubulin complex ( ); GO:0016272 prefoldin complex ( ); GO:0042596 fear response ( ); GO:0006783 heme biosynthetic process ( ); GO:0004004 ATP-dependent RNA helicase activity ( ); GO:0006779 porphyrin biosynthetic process ( ); GO:0033014 tetrapyrrole biosynthetic process ( ); GO:0008186 RNA-dependent ATPase activity ( ); ----------------GO-------------- GO:0015853 adenine transport ( 0.000552958327049713 ); GO:0019718 rough microsome ( 0.000552958327049713 ); GO:0006863 purine transport ( 0.00110563867384261 ); GO:0015851 nucleobase transport ( 0.00221016592971301 ); GO:0034643 mitochondrion localization, microtubule-mediated ( 0.00276201309019242 ); GO:0047497 mitochondrion transport along microtubule ( 0.00276201309019242 ); GO:0051654 establishment of mitochondrion localization ( 0.00276201309019242 ); GO:0008143 poly(A) binding ( 0.00441589020915334 ); GO:0016805 dipeptidase activity ( 0.00441589020915334 ); GO:0048487 beta-tubulin binding ( 0.00496662821306104 ); GO:0001662 behavioral fear response ( 0.00551708924150907 ); GO:0002209 behavioral defense response ( 0.00551708924150907 ); GO:0051646 mitochondrion localization ( 0.00551708924150907 ); GO:0000930 gamma-tubulin complex ( 0.00551708924150907 ); GO:0016272 prefoldin complex ( 0.00551708924150907 ); GO:0042596 fear response ( 0.00716681172756606 ); GO:0006783 heme biosynthetic process ( 0.00826524413812202 ); GO:0004004 ATP-dependent RNA helicase activity ( 0.00936257165270038 ); GO:0006779 porphyrin biosynthetic process ( 0.00991082138664212 ); GO:0033014 tetrapyrrole biosynthetic process ( 0.00991082138664212 ); GO:0008186 RNA-dependent ATPase activity ( 0.00991082138664212 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.000767086758554701 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.000940804057906192 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00125664785721146 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0273456646159053 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2977 ========================= ----------------C2-------------- BIOCARTA_BLYMPHOCYTE_PATHWAY ( 0.00551708924150907 ); REACTOME_A_THIRD_PROTEOLYTIC_CLEAVAGE_RELEASES_NICD ( 0.00551708924150907 ); BIOCARTA_LYM_PATHWAY ( 0.00606727341986968 ); BIOCARTA_MONOCYTE_PATHWAY ( 0.00606727341986968 ); BIOCARTA_TCYTOTOXIC_PATHWAY ( 0.00716681172756606 ); BIOCARTA_THELPER_PATHWAY ( 0.00716681172756606 ); REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY ( 0.00716681172756606 ); BIOCARTA_GRANULOCYTES_PATHWAY ( 0.00771616610739501 ); BIOCARTA_CTL_PATHWAY ( 0.00771616610739501 ); REACTOME_SIGNALING_BY_NOTCH ( 0.00881404594486701 ); BIOCARTA_LAIR_PATHWAY ( 0.00936257165270038 ); ----------------C3-------------- ( 0.00826524413812202 ); ----------------C4-------------- module_412 ( 0.00716681172756606 ); module_275 ( 0.00881404594486701 ); ----------------C5-------------- POST_GOLGI_VESICLE_MEDIATED_TRANSPORT ( 2.52047897915134e-05 ); GOLGI_MEMBRANE ( 0.000247930415125999 ); GOLGI_VESICLE_TRANSPORT ( 0.000296444683543571 ); SECRETORY_PATHWAY ( 0.000879444197846727 ); GOLGI_APPARATUS_PART ( 0.00128352334132873 ); SECRETION_BY_CELL ( 0.00167152437732397 ); SECRETION ( 0.00397231984182802 ); VESICLE_MEDIATED_TRANSPORT ( 0.00457193757097226 ); INTEGRAL_TO_GOLGI_MEMBRANE ( 0.00551708924150907 ); COENZYME_BIOSYNTHETIC_PROCESS ( 0.00551708924150907 ); ENDOMEMBRANE_SYSTEM ( 0.00578233624567934 ); TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE ( 0.00606727341986968 ); GOLGI_APPARATUS ( 0.00632566973561869 ); CELL_FATE_COMMITMENT ( 0.00716681172756606 ); INTRINSIC_TO_GOLGI_MEMBRANE ( 0.00826524413812202 ); REGULATED_SECRETORY_PATHWAY ( 0.00826524413812202 ); INTRACELLULAR_TRANSPORT ( 0.00924465560535374 ); EARLY_ENDOSOME ( 0.00991082138664212 ); REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00991082138664212 ); ----------------GOSLIM-------------- GO:0006892 post-Golgi vesicle-mediated transport ( ); GO:0048193 Golgi vesicle transport ( ); GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell ( ); GO:0007029 endoplasmic reticulum organization ( ); GO:0006432 phenylalanyl-tRNA aminoacylation ( ); GO:0006893 Golgi to plasma membrane transport ( ); GO:0004826 phenylalanine-tRNA ligase activity ( ); GO:0031571 G1 DNA damage checkpoint ( ); GO:0008494 translation activator activity ( ); GO:0006895 Golgi to endosome transport ( ); GO:0006916 anti-apoptosis ( ); GO:0003706 ligand-regulated transcription factor activity ( ); GO:0006743 ubiquinone metabolic process ( ); GO:0006744 ubiquinone biosynthetic process ( ); GO:0042375 quinone cofactor metabolic process ( ); GO:0045426 quinone cofactor biosynthetic process ( ); GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis ( ); GO:0006917 induction of apoptosis ( ); GO:0012502 induction of programmed cell death ( ); GO:0008656 caspase activator activity ( ); GO:0002286 T cell activation during immune response ( ); GO:0031575 G1/S transition checkpoint ( ); GO:0019827 stem cell maintenance ( ); GO:0046579 positive regulation of Ras protein signal transduction ( ); GO:0048864 stem cell development ( ); GO:0016505 apoptotic protease activator activity ( ); GO:0051057 positive regulation of small GTPase mediated signal transduction ( ); GO:0002285 lymphocyte activation during immune response ( ); GO:0045055 regulated secretory pathway ( ); GO:0045768 positive regulation of anti-apoptosis ( ); GO:0000049 tRNA binding ( ); GO:0016504 protease activator activity ( ); GO:0043066 negative regulation of apoptosis ( ); GO:0043069 negative regulation of programmed cell death ( ); GO:0043065 positive regulation of apoptosis ( ); GO:0005506 iron ion binding ( ); GO:0002263 cell activation during immune response ( ); GO:0002366 leukocyte activation during immune response ( ); GO:0007157 heterophilic cell adhesion ( ); GO:0048863 stem cell differentiation ( ); GO:0043068 positive regulation of programmed cell death ( ); ----------------GO-------------- GO:0006892 post-Golgi vesicle-mediated transport ( 4.72914563049835e-05 ); GO:0048193 Golgi vesicle transport ( 0.000990593701981056 ); GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell ( 0.00110563867384261 ); GO:0007029 endoplasmic reticulum organization ( 0.00165804116615509 ); GO:0006432 phenylalanyl-tRNA aminoacylation ( 0.00221016592971301 ); GO:0006893 Golgi to plasma membrane transport ( 0.00276201309019242 ); GO:0004826 phenylalanine-tRNA ligase activity ( 0.00276201309019242 ); GO:0031571 G1 DNA damage checkpoint ( 0.00331358277321803 ); GO:0008494 translation activator activity ( 0.00331358277321803 ); GO:0006895 Golgi to endosome transport ( 0.00386487510436395 ); GO:0006916 anti-apoptosis ( 0.00406197788904367 ); GO:0003706 ligand-regulated transcription factor activity ( 0.00441589020915334 ); GO:0006743 ubiquinone metabolic process ( 0.00496662821306104 ); GO:0006744 ubiquinone biosynthetic process ( 0.00496662821306104 ); GO:0042375 quinone cofactor metabolic process ( 0.00496662821306104 ); GO:0045426 quinone cofactor biosynthetic process ( 0.00496662821306104 ); GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis ( 0.00551708924150907 ); GO:0006917 induction of apoptosis ( 0.00578233624567934 ); GO:0012502 induction of programmed cell death ( 0.00583564553753372 ); GO:0008656 caspase activator activity ( 0.00606727341986968 ); GO:0002286 T cell activation during immune response ( 0.00661718087346486 ); GO:0031575 G1/S transition checkpoint ( 0.00661718087346486 ); GO:0019827 stem cell maintenance ( 0.00716681172756606 ); GO:0046579 positive regulation of Ras protein signal transduction ( 0.00716681172756606 ); GO:0048864 stem cell development ( 0.00716681172756606 ); GO:0016505 apoptotic protease activator activity ( 0.00716681172756606 ); GO:0051057 positive regulation of small GTPase mediated signal transduction ( 0.00771616610739501 ); GO:0002285 lymphocyte activation during immune response ( 0.00826524413812202 ); GO:0045055 regulated secretory pathway ( 0.00826524413812202 ); GO:0045768 positive regulation of anti-apoptosis ( 0.00881404594486701 ); GO:0000049 tRNA binding ( 0.00881404594486701 ); GO:0016504 protease activator activity ( 0.00881404594486701 ); GO:0043066 negative regulation of apoptosis ( 0.00885210718575924 ); GO:0043069 negative regulation of programmed cell death ( 0.00917869018885798 ); GO:0043065 positive regulation of apoptosis ( 0.00924465560535374 ); GO:0005506 iron ion binding ( 0.00924465560535374 ); GO:0002263 cell activation during immune response ( 0.00936257165270038 ); GO:0002366 leukocyte activation during immune response ( 0.00936257165270038 ); GO:0007157 heterophilic cell adhesion ( 0.00936257165270038 ); GO:0048863 stem cell differentiation ( 0.00936257165270038 ); GO:0043068 positive regulation of programmed cell death ( 0.00944384564278453 ); ----------------KEGG-------------- hsa00130 Ubiquinone biosynthesis ( 0.00276201309019242 ); hsa04330 Notch signaling pathway ( 0.0246097015170407 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0482073310849375 ); ============================ group3164 ========================= ----------------C2-------------- BIOCARTA_FIBRINOLYSIS_PATHWAY ( 0.00661718087346486 ); BIOCARTA_EXTRINSIC_PATHWAY ( 0.00716681172756606 ); REACTOME_COMMON_PATHWAY ( 0.00771616610739501 ); REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ ( 0.00826524413812202 ); REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS ( 0.00826524413812202 ); ----------------C3-------------- V$IK2_01 ( 0.00557138507568271 ); V$LEF1_Q6 ( 0.00572925533215594 ); TGANNYRGCA_V$TCF11MAFG_01 ( 0.00605116206622376 ); TTCYNRGAA_V$STAT5B_01 ( 0.00778247523271141 ); WGGAATGY_V$TEF1_Q6 ( 0.00984802858944407 ); ----------------C4-------------- MORF_PTPRR ( 0.0012577083566589 ); MORF_CDH4 ( 0.00231098228967423 ); MORF_MAP2K7 ( 0.00397231984182802 ); MORF_CTSB ( 0.00419823595184666 ); MORF_IL4 ( 0.00433661378389283 ); MORF_IFNA1 ( 0.00486203670141703 ); MORF_MAGEA8 ( 0.00747996957107415 ); module_328 ( 0.00771616610739501 ); module_215 ( 0.00826524413812202 ); module_267 ( 0.00826524413812202 ); MORF_CAMK4 ( 0.00944384564278453 ); ----------------C5-------------- ( 0.00716681172756606 ); ----------------GOSLIM-------------- GO:0016973 poly(A)+ mRNA export from nucleus ( 0.00174309063675273 ); GO:0042405 nuclear inclusion body ( 0.00826524413812202 ); GO:0045211 postsynaptic membrane ( 0.00174309063675273 ); GO:0016933 extracellular-glycine-gated ion channel activity ( 0.00826524413812202 ); GO:0016934 extracellular-glycine-gated chloride channel activity ( 0.00174309063675273 ); GO:0044425 membrane part ( 0.00826524413812202 ); GO:0016234 inclusion body ( 0.00174309063675273 ); GO:0005577 fibrinogen complex ( 0.00826524413812202 ); GO:0005487 nucleocytoplasmic transporter activity ( 0.00174309063675273 ); GO:0044456 synapse part ( 0.00826524413812202 ); GO:0005886 plasma membrane ( 0.00174309063675273 ); GO:0003796 lysozyme activity ( 0.00826524413812202 ); GO:0016998 cell wall catabolic process ( 0.00174309063675273 ); GO:0042246 tissue regeneration ( 0.00826524413812202 ); GO:0043499 eukaryotic cell surface binding ( 0.00174309063675273 ); GO:0007047 cell wall organization ( 0.00826524413812202 ); GO:0044036 cell wall metabolic process ( 0.00174309063675273 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00826524413812202 ); GO:0004872 receptor activity ( 0.00174309063675273 ); GO:0045202 synapse ( 0.00826524413812202 ); GO:0004089 carbonate dehydratase activity ( 0.00174309063675273 ); GO:0016020 membrane ( 0.00826524413812202 ); GO:0045229 external encapsulating structure organization ( 0.00174309063675273 ); ----------------GO-------------- GO:0016973 poly(A)+ mRNA export from nucleus ( 0.00165804116615509 ); GO:0042405 nuclear inclusion body ( 0.00165804116615509 ); GO:0045211 postsynaptic membrane ( 0.00188401156559414 ); GO:0016933 extracellular-glycine-gated ion channel activity ( 0.00221016592971301 ); GO:0016934 extracellular-glycine-gated chloride channel activity ( 0.00221016592971301 ); GO:0044425 membrane part ( 0.00251484361505251 ); GO:0016234 inclusion body ( 0.00331358277321803 ); GO:0005577 fibrinogen complex ( 0.00386487510436395 ); GO:0005487 nucleocytoplasmic transporter activity ( 0.00386487510436395 ); GO:0044456 synapse part ( 0.00410716133710249 ); GO:0005886 plasma membrane ( 0.00474600257229313 ); GO:0003796 lysozyme activity ( 0.00496662821306104 ); GO:0016998 cell wall catabolic process ( 0.00771616610739501 ); GO:0042246 tissue regeneration ( 0.00771616610739501 ); GO:0043499 eukaryotic cell surface binding ( 0.00771616610739501 ); GO:0007047 cell wall organization ( 0.00826524413812202 ); GO:0044036 cell wall metabolic process ( 0.00826524413812202 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00826524413812202 ); GO:0004872 receptor activity ( 0.00843865984953434 ); GO:0045202 synapse ( 0.00878744089817184 ); GO:0004089 carbonate dehydratase activity ( 0.00881404594486701 ); GO:0016020 membrane ( 0.00903350570557703 ); GO:0045229 external encapsulating structure organization ( 0.00936257165270038 ); ----------------KEGG-------------- hsa00910 Nitrogen metabolism ( 0.0131945313333189 ); hsa04610 Complement and coagulation cascades ( 0.0369741896203146 ); ----------------CARTA-------------- proteasomepathway ( 0.00496662821306104 ); intrinsicpathway ( 0.00716681172756606 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3186 ========================= ----------------C2-------------- REACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENES_FAMILY ( 0.00551708924150907 ); KEGG_REGULATION_OF_ACTIN_CYTOSKELETON ( 0.00572925533215594 ); REACTOME_ZINC_TRANSPORTATION ( 0.00936257165270038 ); ----------------C3-------------- V$HNF3ALPHA_Q6 ( 0.00345431452070648 ); V$IPF1_Q4 ( 0.00438320973509662 ); V$NFY_Q6 ( 0.00447710529677059 ); V$EVI1_04 ( 0.00452440445722293 ); V$FREAC3_01 ( 0.00461970441335757 ); V$LYF1_01 ( 0.00541557820076729 ); V$AP1_Q2 ( 0.00594294837155327 ); AGCGCTT,MIR-518F,MIR-518E,MIR-518A ( 0.00881404594486701 ); CGCTGCT,MIR-503 ( 0.00991082138664212 ); ----------------C4-------------- module_26 ( 0.00415258076667528 ); module_49 ( 0.0075400279680789 ); ----------------C5-------------- SINGLE_STRANDED_RNA_BINDING ( 0.00661718087346486 ); EXTRINSIC_TO_PLASMA_MEMBRANE ( 0.00716681172756606 ); INSULIN_RECEPTOR_SIGNALING_PATHWAY ( 0.00991082138664212 ); ----------------GOSLIM-------------- GO:0065007 biological regulation ( ); GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening ( ); GO:0050779 RNA destabilization ( ); GO:0016342 catenin complex ( ); GO:0007165 signal transduction ( ); GO:0050794 regulation of cellular process ( ); GO:0006198 cAMP catabolic process ( ); GO:0021985 neurohypophysis development ( ); GO:0000156 two-component response regulator activity ( ); GO:0005093 Rab GDP-dissociation inhibitor activity ( ); GO:0017091 AU-rich element binding ( ); GO:0050789 regulation of biological process ( ); GO:0043087 regulation of GTPase activity ( ); GO:0007154 cell communication ( ); GO:0009214 cyclic nucleotide catabolic process ( ); GO:0021979 hypothalamus cell differentiation ( ); GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ( ); GO:0006882 cellular zinc ion homeostasis ( ); GO:0021854 hypothalamus development ( ); GO:0055069 zinc ion homeostasis ( ); GO:0005092 GDP-dissociation inhibitor activity ( ); GO:0030154 cell differentiation ( ); GO:0002052 positive regulation of neuroblast proliferation ( ); GO:0000160 two-component signal transduction system (phosphorelay) ( ); GO:0046847 filopodium formation ( ); GO:0030035 microspike assembly ( ); GO:0055038 recycling endosome membrane ( ); GO:0005385 zinc ion transmembrane transporter activity ( ); GO:0005096 GTPase activator activity ( ); GO:0007242 intracellular signaling cascade ( ); GO:0043487 regulation of RNA stability ( ); GO:0043488 regulation of mRNA stability ( ); GO:0048869 cellular developmental process ( ); GO:0008093 cytoskeletal adaptor activity ( ); GO:0005083 small GTPase regulator activity ( ); GO:0021983 pituitary gland development ( ); GO:0050728 negative regulation of inflammatory response ( ); GO:0007399 nervous system development ( ); GO:0031348 negative regulation of defense response ( ); GO:0051336 regulation of hydrolase activity ( ); GO:0055037 recycling endosome ( ); ----------------GO-------------- GO:0065007 biological regulation ( 0.000175437675473186 ); GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening ( 0.000552958327049713 ); GO:0050779 RNA destabilization ( 0.000552958327049713 ); GO:0016342 catenin complex ( 0.000552958327049713 ); GO:0007165 signal transduction ( 0.000812945762060195 ); GO:0050794 regulation of cellular process ( 0.000859324710911679 ); GO:0006198 cAMP catabolic process ( 0.00110563867384261 ); GO:0021985 neurohypophysis development ( 0.00110563867384261 ); GO:0000156 two-component response regulator activity ( 0.00110563867384261 ); GO:0005093 Rab GDP-dissociation inhibitor activity ( 0.00110563867384261 ); GO:0017091 AU-rich element binding ( 0.00110563867384261 ); GO:0050789 regulation of biological process ( 0.00114473282634923 ); GO:0043087 regulation of GTPase activity ( 0.0013095926018128 ); GO:0007154 cell communication ( 0.00141984073448765 ); GO:0009214 cyclic nucleotide catabolic process ( 0.00165804116615509 ); GO:0021979 hypothalamus cell differentiation ( 0.00165804116615509 ); GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ( 0.00221016592971301 ); GO:0006882 cellular zinc ion homeostasis ( 0.00276201309019242 ); GO:0021854 hypothalamus development ( 0.00331358277321803 ); GO:0055069 zinc ion homeostasis ( 0.00331358277321803 ); GO:0005092 GDP-dissociation inhibitor activity ( 0.00331358277321803 ); GO:0030154 cell differentiation ( 0.00368749606806123 ); GO:0002052 positive regulation of neuroblast proliferation ( 0.00386487510436395 ); GO:0000160 two-component signal transduction system (phosphorelay) ( 0.00496662821306104 ); GO:0046847 filopodium formation ( 0.00496662821306104 ); GO:0030035 microspike assembly ( 0.00551708924150907 ); GO:0055038 recycling endosome membrane ( 0.00551708924150907 ); GO:0005385 zinc ion transmembrane transporter activity ( 0.00551708924150907 ); GO:0005096 GTPase activator activity ( 0.00572925533215594 ); GO:0007242 intracellular signaling cascade ( 0.00594135712745553 ); GO:0043487 regulation of RNA stability ( 0.00606727341986968 ); GO:0043488 regulation of mRNA stability ( 0.00606727341986968 ); GO:0048869 cellular developmental process ( 0.00656958685569163 ); GO:0008093 cytoskeletal adaptor activity ( 0.00716681172756606 ); GO:0005083 small GTPase regulator activity ( 0.00742013297575119 ); GO:0021983 pituitary gland development ( 0.00771616610739501 ); GO:0050728 negative regulation of inflammatory response ( 0.00771616610739501 ); GO:0007399 nervous system development ( 0.0078249071716526 ); GO:0031348 negative regulation of defense response ( 0.00826524413812202 ); GO:0051336 regulation of hydrolase activity ( 0.00885210718575924 ); GO:0055037 recycling endosome ( 0.00991082138664212 ); ----------------KEGG-------------- hsa04810 Regulation of actin cytoskeleton ( 0.00572925533215594 ); hsa05050 Dentatorubropallidoluysian atrophy (DRPLA) ( 0.00771616610739501 ); hsa05213 Endometrial cancer ( 0.0283879971992282 ); hsa05217 Basal cell carcinoma ( 0.0300031898634638 ); hsa04520 Adherens junction ( 0.0407089111985536 ); hsa05210 Colorectal cancer ( 0.0454913477301566 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0146937940491693 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3224 ========================= ----------------C2-------------- BIOCARTA_VDR_PATHWAY ( 0.00661718087346486 ); BIOCARTA_RARRXR_PATHWAY ( 0.00826524413812202 ); ----------------C3-------------- TATCTGG,MIR-488 ( 0.000309240274847399 ); ATGTCAC,MIR-489 ( 0.000754592324300932 ); CTTTGTA,MIR-524 ( 0.000957284480347437 ); GACAATC,MIR-219 ( 0.00207587021244941 ); CATGTAA,MIR-496 ( 0.00300974934910112 ); ACTGAAA,MIR-30A-3P,MIR-30E-3P ( 0.00353826549452075 ); TGTGTGA,MIR-377 ( 0.00353826549452075 ); V$NRF2_Q4 ( 0.00457193757097226 ); V$ATF4_Q2 ( 0.00461970441335757 ); GTTTGTT,MIR-495 ( 0.00541557820076729 ); GTACTGT,MIR-101 ( 0.00632566973561869 ); CATTTCA,MIR-203 ( 0.00730112605927511 ); TATTATA,MIR-374 ( 0.00742013297575119 ); ATGTACA,MIR-493 ( 0.00853095059952927 ); ----------------C4-------------- ( ); ----------------C5-------------- PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY ( 0.00293205513664063 ); 3__5__CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY ( 0.00716681172756606 ); INSOLUBLE_FRACTION ( 0.00771616610739501 ); CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY ( 0.00771616610739501 ); HYDROLASE_ACTIVITY__ACTING_ON_ESTER_BONDS ( 0.00872299188127246 ); ----------------GOSLIM-------------- GO:0006797 polyphosphate metabolic process ( ); GO:0004446 multiple inositol-polyphosphate phosphatase activity ( ); GO:0034417 bisphosphoglycerate 3-phosphatase activity ( ); GO:0008969 phosphohistidine phosphatase activity ( ); GO:0004652 polynucleotide adenylyltransferase activity ( ); GO:0034416 bisphosphoglycerate phosphatase activity ( ); GO:0012507 ER to Golgi transport vesicle membrane ( ); GO:0030127 COPII vesicle coat ( ); GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity ( ); GO:0030134 ER to Golgi transport vesicle ( ); GO:0003993 acid phosphatase activity ( ); GO:0043631 RNA polyadenylation ( ); GO:0031123 RNA 3'-end processing ( ); GO:0000209 protein polyubiquitination ( ); ----------------GO-------------- GO:0006797 polyphosphate metabolic process ( 0.000552958327049713 ); GO:0004446 multiple inositol-polyphosphate phosphatase activity ( 0.000552958327049713 ); GO:0034417 bisphosphoglycerate 3-phosphatase activity ( 0.000552958327049713 ); GO:0008969 phosphohistidine phosphatase activity ( 0.00110563867384261 ); GO:0004652 polynucleotide adenylyltransferase activity ( 0.00276201309019242 ); GO:0034416 bisphosphoglycerate phosphatase activity ( 0.00276201309019242 ); GO:0012507 ER to Golgi transport vesicle membrane ( 0.00331358277321803 ); GO:0030127 COPII vesicle coat ( 0.00331358277321803 ); GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity ( 0.00386487510436395 ); GO:0030134 ER to Golgi transport vesicle ( 0.00441589020915334 ); GO:0003993 acid phosphatase activity ( 0.00551708924150907 ); GO:0043631 RNA polyadenylation ( 0.00606727341986968 ); GO:0031123 RNA 3'-end processing ( 0.00826524413812202 ); GO:0000209 protein polyubiquitination ( 0.00881404594486701 ); ----------------KEGG-------------- hsa03050 Proteasome ( 0.0240688560042213 ); hsa00562 Inositol phosphate metabolism ( 0.0262306035874679 ); hsa04742 Taste transduction ( 0.026770359866658 ); ----------------CARTA-------------- smrtepathway ( 0.00276201309019242 ); pyk2pathway ( 0.0208180536333654 ); p38mapkpathway ( 0.0229863470029374 ); ----------------RBP-------------- PUM2_PAR-CLIP_(Hafner_2010) ( 0.00222754716183724 ); ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.0031615614442466 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.00323755733180566 ); QKI_PAR-CLIP_(Hafner_2010) ( 0.0143863672822525 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0186059687253293 ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_C5 ( 0.0192465388969939 ); ARE_ALL ( 0.0482073310849375 ); ============================ group9 ========================= ----------------C2-------------- ( 0.00701698780579418 ); ----------------C3-------------- V$MYCMAX_B ( 0.00396307671590615 ); CTGAGCC,MIR-24 ( 0.00404411813318692 ); V$ZIC1_01 ( 0.00408492973498161 ); V$AP3_Q6 ( 0.00408492973498161 ); CTCAGGG,MIR-125B,MIR-125A ( 0.0080195255907171 ); ----------------C4-------------- ( ); ----------------C5-------------- PROTEIN_MODIFICATION_PROCESS ( 0.00288967111383011 ); BIOPOLYMER_MODIFICATION ( 0.00312549809685257 ); FUCOSYLTRANSFERASE_ACTIVITY ( 0.00501667012473783 ); SECRETIN_LIKE_RECEPTOR_ACTIVITY ( 0.00501667012473783 ); GOLGI_APPARATUS ( 0.00521354230307148 ); ADENYLATE_CYCLASE_ACTIVATION ( 0.00901368545837389 ); ----------------GOSLIM-------------- GO:0005042 netrin receptor activity ( 0.00778972347900239 ); GO:0015056 corticotrophin-releasing factor receptor activity ( 0.00985986361567313 ); GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity ( 0.00778972347900239 ); GO:0031127 alpha(1,2)-fucosyltransferase activity ( 0.00985986361567313 ); GO:0042801 polo kinase kinase activity ( 0.00778972347900239 ); GO:0007567 parturition ( 0.00985986361567313 ); GO:0004726 non-membrane spanning protein tyrosine phosphatase activity ( 0.00778972347900239 ); GO:0007420 brain development ( 0.00985986361567313 ); GO:0019317 fucose catabolic process ( 0.00778972347900239 ); GO:0042355 L-fucose catabolic process ( 0.00985986361567313 ); GO:0042354 L-fucose metabolic process ( 0.00778972347900239 ); GO:0007263 nitric oxide mediated signal transduction ( 0.00985986361567313 ); GO:0009746 response to hexose stimulus ( 0.00778972347900239 ); GO:0009749 response to glucose stimulus ( 0.00985986361567313 ); GO:0034284 response to monosaccharide stimulus ( 0.00778972347900239 ); GO:0008417 fucosyltransferase activity ( 0.00985986361567313 ); GO:0031018 endocrine pancreas development ( 0.00778972347900239 ); GO:0048562 embryonic organ morphogenesis ( 0.00985986361567313 ); GO:0003746 translation elongation factor activity ( 0.00778972347900239 ); GO:0006004 fucose metabolic process ( 0.00985986361567313 ); GO:0007417 central nervous system development ( 0.00778972347900239 ); GO:0009743 response to carbohydrate stimulus ( 0.00985986361567313 ); ----------------GO-------------- GO:0005042 netrin receptor activity ( 0.001005151338062 ); GO:0015056 corticotrophin-releasing factor receptor activity ( 0.001005151338062 ); GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity ( 0.00150738594097877 ); GO:0031127 alpha(1,2)-fucosyltransferase activity ( 0.00150738594097877 ); GO:0042801 polo kinase kinase activity ( 0.00150738594097877 ); GO:0007567 parturition ( 0.00301272658247664 ); GO:0004726 non-membrane spanning protein tyrosine phosphatase activity ( 0.00351405271181648 ); GO:0007420 brain development ( 0.00353127000677185 ); GO:0019317 fucose catabolic process ( 0.00451602439168231 ); GO:0042355 L-fucose catabolic process ( 0.00451602439168231 ); GO:0042354 L-fucose metabolic process ( 0.00551708924150862 ); GO:0007263 nitric oxide mediated signal transduction ( 0.00651724799090048 ); GO:0009746 response to hexose stimulus ( 0.00651724799090048 ); GO:0009749 response to glucose stimulus ( 0.00651724799090048 ); GO:0034284 response to monosaccharide stimulus ( 0.00651724799090048 ); GO:0008417 fucosyltransferase activity ( 0.00701698780579418 ); GO:0031018 endocrine pancreas development ( 0.00751650136894844 ); GO:0048562 embryonic organ morphogenesis ( 0.00751650136894844 ); GO:0003746 translation elongation factor activity ( 0.00751650136894844 ); GO:0006004 fucose metabolic process ( 0.00851485010423025 ); GO:0007417 central nervous system development ( 0.00893958832769736 ); GO:0009743 response to carbohydrate stimulus ( 0.00901368545837389 ); ----------------KEGG-------------- hsa00603 Glycosphingolipid biosynthesis - globo series ( 0.00701698780579418 ); hsa04950 Maturity onset diabetes of the young ( 0.0115044757315573 ); hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series ( 0.0129962439679628 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0312288576902144 ); hsa04730 Long-term depression ( 0.0365905964493483 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2745 ========================= ----------------C2-------------- ( 0.00851485010423025 ); ----------------C3-------------- V$PU1_Q6 ( 0.00308726765851081 ); TGCACGA,MIR-517A,MIR-517C ( 0.00701698780579418 ); ----------------C4-------------- ( ); ----------------C5-------------- REGULATION_OF_CELL_CELL_ADHESION ( 0.00501667012473783 ); APOPTOTIC_MITOCHONDRIAL_CHANGES ( 0.00551708924150862 ); NF_KAPPAB_BINDING ( 0.00551708924150862 ); NEGATIVE_REGULATION_OF_PHOSPHORYLATION ( 0.00601728183317907 ); AGING ( 0.00601728183317907 ); G2_M_TRANSITION_OF_MITOTIC_CELL_CYCLE ( 0.00651724799090048 ); DNA_FRAGMENTATION_DURING_APOPTOSIS ( 0.00651724799090048 ); NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS ( 0.00651724799090048 ); NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00751650136894844 ); NEGATIVE_REGULATION_OF_DNA_BINDING ( 0.00851485010423025 ); NEGATIVE_REGULATION_OF_CELL_ADHESION ( 0.00851485010423025 ); CELL_STRUCTURE_DISASSEMBLY_DURING_APOPTOSIS ( 0.00901368545837389 ); NEGATIVE_REGULATION_OF_BINDING ( 0.00901368545837389 ); TRANSCRIPTION_FACTOR_BINDING ( 0.00935649244341066 ); APOPTOTIC_NUCLEAR_CHANGES ( 0.00951229492480987 ); ----------------GOSLIM-------------- GO:0005550 pheromone binding ( ); GO:0055103 ligase regulator activity ( ); GO:0055104 ligase inhibitor activity ( ); GO:0055105 ubiquitin-protein ligase inhibitor activity ( ); GO:0055106 ubiquitin-protein ligase regulator activity ( ); GO:0010389 regulation of G2/M transition of mitotic cell cycle ( ); GO:0033079 immature T cell proliferation ( ); GO:0033080 immature T cell proliferation in the thymus ( ); GO:0033083 regulation of immature T cell proliferation ( ); GO:0033084 regulation of immature T cell proliferation in the thymus ( ); GO:0033087 negative regulation of immature T cell proliferation ( ); GO:0033088 negative regulation of immature T cell proliferation in the thymus ( ); GO:0005549 odorant binding ( ); GO:0017145 stem cell division ( ); GO:0030889 negative regulation of B cell proliferation ( ); GO:0048103 somatic stem cell division ( ); GO:0033081 regulation of T cell differentiation in the thymus ( ); GO:0010149 senescence ( ); GO:0032088 negative regulation of NF-kappaB transcription factor activity ( ); GO:0001953 negative regulation of cell-matrix adhesion ( ); GO:0010812 negative regulation of cell-substrate adhesion ( ); GO:0045736 negative regulation of cyclin-dependent protein kinase activity ( ); GO:0004861 cyclin-dependent protein kinase inhibitor activity ( ); GO:0050869 negative regulation of B cell activation ( ); GO:0030888 regulation of B cell proliferation ( ); GO:0000086 G2/M transition of mitotic cell cycle ( ); GO:0016538 cyclin-dependent protein kinase regulator activity ( ); GO:0006309 DNA fragmentation during apoptosis ( ); GO:0042130 negative regulation of T cell proliferation ( ); GO:0030291 protein serine/threonine kinase inhibitor activity ( ); GO:0032945 negative regulation of mononuclear cell proliferation ( ); GO:0050672 negative regulation of lymphocyte proliferation ( ); ----------------GO-------------- GO:0005550 pheromone binding ( 0.000502689388227062 ); GO:0055103 ligase regulator activity ( 0.000502689388227062 ); GO:0055104 ligase inhibitor activity ( 0.000502689388227062 ); GO:0055105 ubiquitin-protein ligase inhibitor activity ( 0.000502689388227062 ); GO:0055106 ubiquitin-protein ligase regulator activity ( 0.000502689388227062 ); GO:0010389 regulation of G2/M transition of mitotic cell cycle ( 0.001005151338062 ); GO:0033079 immature T cell proliferation ( 0.001005151338062 ); GO:0033080 immature T cell proliferation in the thymus ( 0.001005151338062 ); GO:0033083 regulation of immature T cell proliferation ( 0.001005151338062 ); GO:0033084 regulation of immature T cell proliferation in the thymus ( 0.001005151338062 ); GO:0033087 negative regulation of immature T cell proliferation ( 0.001005151338062 ); GO:0033088 negative regulation of immature T cell proliferation in the thymus ( 0.001005151338062 ); GO:0005549 odorant binding ( 0.00150738594097877 ); GO:0017145 stem cell division ( 0.0020093932884192 ); GO:0030889 negative regulation of B cell proliferation ( 0.0020093932884192 ); GO:0048103 somatic stem cell division ( 0.0020093932884192 ); GO:0033081 regulation of T cell differentiation in the thymus ( 0.00301272658247664 ); GO:0010149 senescence ( 0.00351405271181648 ); GO:0032088 negative regulation of NF-kappaB transcription factor activity ( 0.00451602439168231 ); GO:0001953 negative regulation of cell-matrix adhesion ( 0.00501667012473783 ); GO:0010812 negative regulation of cell-substrate adhesion ( 0.00501667012473783 ); GO:0045736 negative regulation of cyclin-dependent protein kinase activity ( 0.00501667012473783 ); GO:0004861 cyclin-dependent protein kinase inhibitor activity ( 0.00501667012473783 ); GO:0050869 negative regulation of B cell activation ( 0.00601728183317907 ); GO:0030888 regulation of B cell proliferation ( 0.00651724799090048 ); GO:0000086 G2/M transition of mitotic cell cycle ( 0.00751650136894844 ); GO:0016538 cyclin-dependent protein kinase regulator activity ( 0.00751650136894844 ); GO:0006309 DNA fragmentation during apoptosis ( 0.00801578877141895 ); GO:0042130 negative regulation of T cell proliferation ( 0.00801578877141895 ); GO:0030291 protein serine/threonine kinase inhibitor activity ( 0.00801578877141895 ); GO:0032945 negative regulation of mononuclear cell proliferation ( 0.00951229492480987 ); GO:0050672 negative regulation of lymphocyte proliferation ( 0.00951229492480987 ); ----------------KEGG-------------- hsa05219 Bladder cancer ( 0.0209181763751527 ); hsa05223 Non-small cell lung cancer ( 0.0268220213932411 ); hsa05214 Glioma ( 0.0317173958356051 ); hsa04115 p53 signaling pathway ( 0.0331816802014512 ); hsa05218 Melanoma ( 0.0351309591964324 ); hsa05212 Pancreatic cancer ( 0.0356177259408597 ); hsa05220 Chronic myeloid leukemia ( 0.0365905964493483 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2760 ========================= ----------------C2-------------- ( 0.00601728183317907 ); ----------------C3-------------- ( 0.00460538266149851 ); ----------------C4-------------- ( ); ----------------C5-------------- ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00501667012473783 ); NEGATIVE_REGULATION_OF_ANGIOGENESIS ( 0.00651724799090048 ); REGULATION_OF_NEUROGENESIS ( 0.00701698780579418 ); VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX ( 0.00751650136894844 ); ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00790775596590366 ); VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY ( 0.00901368545837389 ); ----------------GOSLIM-------------- GO:0001741 XY body ( ); GO:0004946 bombesin receptor activity ( ); GO:0009134 nucleoside diphosphate catabolic process ( ); GO:0000803 sex chromosome ( ); GO:0001739 sex chromatin ( ); GO:0017110 nucleoside-diphosphatase activity ( ); GO:0009132 nucleoside diphosphate metabolic process ( ); GO:0009143 nucleoside triphosphate catabolic process ( ); GO:0008514 organic anion transmembrane transporter activity ( ); GO:0005720 nuclear heterochromatin ( ); GO:0005452 inorganic anion exchanger activity ( ); GO:0015711 organic anion transport ( ); GO:0015380 anion exchanger activity ( ); GO:0015106 bicarbonate transmembrane transporter activity ( ); GO:0015108 chloride transmembrane transporter activity ( ); GO:0015301 anion:anion antiporter activity ( ); ----------------GO-------------- GO:0001741 XY body ( 0.000502689388227062 ); GO:0004946 bombesin receptor activity ( 0.00150738594097877 ); GO:0009134 nucleoside diphosphate catabolic process ( 0.0020093932884192 ); GO:0000803 sex chromosome ( 0.00301272658247664 ); GO:0001739 sex chromatin ( 0.00301272658247664 ); GO:0017110 nucleoside-diphosphatase activity ( 0.00301272658247664 ); GO:0009132 nucleoside diphosphate metabolic process ( 0.00451602439168231 ); GO:0009143 nucleoside triphosphate catabolic process ( 0.00551708924150862 ); GO:0008514 organic anion transmembrane transporter activity ( 0.00551708924150862 ); GO:0005720 nuclear heterochromatin ( 0.00601728183317907 ); GO:0005452 inorganic anion exchanger activity ( 0.00651724799090048 ); GO:0015711 organic anion transport ( 0.00751650136894844 ); GO:0015380 anion exchanger activity ( 0.00851485010423025 ); GO:0015106 bicarbonate transmembrane transporter activity ( 0.00901368545837389 ); GO:0015108 chloride transmembrane transporter activity ( 0.00901368545837389 ); GO:0015301 anion:anion antiporter activity ( 0.00951229492480987 ); ----------------KEGG-------------- hsa04930 Type II diabetes mellitus ( 0.0204247372946039 ); hsa04330 Notch signaling pathway ( 0.0223971516918701 ); hsa04742 Taste transduction ( 0.0243659909866273 ); hsa00240 Pyrimidine metabolism ( 0.0448244012277662 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2774 ========================= ----------------C2-------------- REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING ( 0.00651724799090048 ); REACTOME_SIGNALING_BY_TGF_BETA ( 0.00751650136894844 ); REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS ( 0.00801578877141895 ); ----------------C3-------------- CCTNTMAGA_UNKNOWN ( 0.000929350481239082 ); V$ALPHACP1_01 ( 0.00360802254688799 ); SCGGAAGY_V$ELK1_02 ( 0.00586011520679115 ); ----------------C4-------------- MORF_ERH ( 0.00118528503262949 ); MORF_PRKAR1A ( 0.00189904412641522 ); MORF_DAP3 ( 0.00334282204120725 ); MORF_RAN ( 0.00636907611868136 ); MORF_SOD1 ( 0.00652107914422828 ); MORF_CSNK2B ( 0.00703976246575418 ); module_151 ( 0.0092964023800455 ); ----------------C5-------------- GLUCAN_METABOLIC_PROCESS ( 0.00501667012473783 ); CELLULAR_POLYSACCHARIDE_METABOLIC_PROCESS ( 0.00701698780579418 ); POLYSACCHARIDE_METABOLIC_PROCESS ( 0.00801578877141895 ); FEMALE_GAMETE_GENERATION ( 0.00851485010423025 ); ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT ( 0.00851485010423025 ); ----------------GOSLIM-------------- GO:0005982 starch metabolic process ( 0.00172135653363622 ); GO:0005983 starch catabolic process ( 0.00172135653363622 ); GO:0004339 glucan 1,4-alpha-glucosidase activity ( 0.00172135653363622 ); GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity ( 0.00172135653363622 ); GO:0034616 response to laminar fluid shear stress ( 0.00172135653363622 ); GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ( 0.00172135653363622 ); GO:0042801 polo kinase kinase activity ( 0.00172135653363622 ); GO:0004558 alpha-glucosidase activity ( 0.00172135653363622 ); GO:0005057 receptor signaling protein activity ( 0.00172135653363622 ); GO:0009251 glucan catabolic process ( 0.00172135653363622 ); GO:0034405 response to fluid shear stress ( 0.00172135653363622 ); GO:0005868 cytoplasmic dynein complex ( 0.00172135653363622 ); GO:0000272 polysaccharide catabolic process ( 0.00172135653363622 ); GO:0015926 glucosidase activity ( 0.00172135653363622 ); GO:0017169 CDP-alcohol phosphatidyltransferase activity ( 0.00172135653363622 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00172135653363622 ); GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity ( 0.00172135653363622 ); GO:0005071 transmembrane receptor protein serine/threonine kinase signaling protein activity ( 0.00172135653363622 ); GO:0005753 mitochondrial proton-transporting ATP synthase complex ( 0.00172135653363622 ); GO:0016780 phosphotransferase activity, for other substituted phosphate groups ( 0.00172135653363622 ); GO:0045259 proton-transporting ATP synthase complex ( 0.00172135653363622 ); ----------------GO-------------- GO:0005982 starch metabolic process ( 0.000502689388227062 ); GO:0005983 starch catabolic process ( 0.000502689388227062 ); GO:0004339 glucan 1,4-alpha-glucosidase activity ( 0.000502689388227062 ); GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity ( 0.000502689388227062 ); GO:0034616 response to laminar fluid shear stress ( 0.001005151338062 ); GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ( 0.001005151338062 ); GO:0042801 polo kinase kinase activity ( 0.00150738594097877 ); GO:0004558 alpha-glucosidase activity ( 0.0020093932884192 ); GO:0005057 receptor signaling protein activity ( 0.00247482260572562 ); GO:0009251 glucan catabolic process ( 0.00301272658247664 ); GO:0034405 response to fluid shear stress ( 0.00301272658247664 ); GO:0005868 cytoplasmic dynein complex ( 0.00301272658247664 ); GO:0000272 polysaccharide catabolic process ( 0.00401515195112467 ); GO:0015926 glucosidase activity ( 0.00401515195112467 ); GO:0017169 CDP-alcohol phosphatidyltransferase activity ( 0.00401515195112467 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00551708924150862 ); GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity ( 0.00551708924150862 ); GO:0005071 transmembrane receptor protein serine/threonine kinase signaling protein activity ( 0.00601728183317907 ); GO:0005753 mitochondrial proton-transporting ATP synthase complex ( 0.00901368545837389 ); GO:0016780 phosphotransferase activity, for other substituted phosphate groups ( 0.00901368545837389 ); GO:0045259 proton-transporting ATP synthase complex ( 0.00951229492480987 ); ----------------KEGG-------------- hsa00052 Galactose metabolism ( 0.0124992131712907 ); hsa04130 SNARE interactions in vesicular transport ( 0.0189430768653164 ); hsa00500 Starch and sucrose metabolism ( 0.021411391741444 ); hsa00564 Glycerophospholipid metabolism ( 0.0322057122429704 ); hsa04115 p53 signaling pathway ( 0.0331816802014512 ); hsa04350 TGF-beta signaling pathway ( 0.0424092934761842 ); ----------------CARTA-------------- s1ppathway ( 0.00301272658247664 ); tgfbpathway ( 0.00651724799090048 ); ----------------RBP-------------- ( 0.0289448316912641 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2775 ========================= ----------------C2-------------- ( 0.00551708924150862 ); ----------------C3-------------- V$LBP1_Q6 ( 0.00284141667560656 ); V$GR_Q6_01 ( 0.00416713389981162 ); V$LEF1_Q6 ( 0.0047202566132 ); GTGCCAA,MIR-96 ( 0.00741376804717744 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005277 acetylcholine transmembrane transporter activity ( ); GO:0030899 calcium-dependent ATPase activity ( ); GO:0015870 acetylcholine transport ( ); GO:0030172 troponin C binding ( ); GO:0031013 troponin I binding ( ); GO:0005861 troponin complex ( ); GO:0003009 skeletal muscle contraction ( ); GO:0005523 tropomyosin binding ( ); GO:0005865 striated muscle thin filament ( ); GO:0050879 multicellular organismal movement ( ); GO:0050881 musculoskeletal movement ( ); GO:0043462 regulation of ATPase activity ( ); GO:0006942 regulation of striated muscle contraction ( ); GO:0048306 calcium-dependent protein binding ( ); ----------------GO-------------- GO:0005277 acetylcholine transmembrane transporter activity ( 0.000502689388227062 ); GO:0030899 calcium-dependent ATPase activity ( 0.000502689388227062 ); GO:0015870 acetylcholine transport ( 0.001005151338062 ); GO:0030172 troponin C binding ( 0.00150738594097877 ); GO:0031013 troponin I binding ( 0.00251117347179275 ); GO:0005861 troponin complex ( 0.00351405271181648 ); GO:0003009 skeletal muscle contraction ( 0.00501667012473783 ); GO:0005523 tropomyosin binding ( 0.00551708924150862 ); GO:0005865 striated muscle thin filament ( 0.00601728183317907 ); GO:0050879 multicellular organismal movement ( 0.00651724799090048 ); GO:0050881 musculoskeletal movement ( 0.00651724799090048 ); GO:0043462 regulation of ATPase activity ( 0.00701698780579418 ); GO:0006942 regulation of striated muscle contraction ( 0.00751650136894844 ); GO:0048306 calcium-dependent protein binding ( 0.00851485010423025 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2900 ========================= ----------------C2-------------- REACTOME_RNA_POLYMERASE_III_CHAIN_ELONGATION ( 0.00601728183317907 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION ( 0.00851485010423025 ); ----------------C3-------------- ( ); ----------------C4-------------- module_540 ( 0.00501667012473783 ); module_262 ( 0.00901368545837389 ); module_191 ( 0.00951229492480987 ); ----------------C5-------------- POSITIVE_REGULATION_OF_DEFENSE_RESPONSE ( 0.00501667012473783 ); DETECTION_OF_BIOTIC_STIMULUS ( 0.00501667012473783 ); ISOPRENOID_METABOLIC_PROCESS ( 0.00551708924150862 ); IMMUNE_RESPONSE ( 0.00558670611806421 ); T_CELL_DIFFERENTIATION ( 0.00751650136894844 ); OXIDOREDUCTASE_ACTIVITY__ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS__NAD_OR_NADP_AS_ACCEPTOR ( 0.00801578877141895 ); VITAMIN_METABOLIC_PROCESS ( 0.00851485010423025 ); ----------------GOSLIM-------------- GO:0009617 response to bacterium ( ); GO:0051707 response to other organism ( ); GO:0009607 response to biotic stimulus ( ); GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib ( ); GO:0030882 lipid antigen binding ( ); GO:0030884 exogenous lipid antigen binding ( ); GO:0002475 antigen processing and presentation via MHC class Ib ( ); GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib ( ); GO:0004947 bradykinin receptor activity ( ); GO:0030881 beta-2-microglobulin binding ( ); GO:0042574 retinal metabolic process ( ); GO:0043288 apocarotenoid metabolic process ( ); GO:0001758 retinal dehydrogenase activity ( ); GO:0004064 arylesterase activity ( ); GO:0051704 multi-organism process ( ); GO:0030005 cellular di-, tri-valent inorganic cation homeostasis ( ); GO:0055066 di-, tri-valent inorganic cation homeostasis ( ); GO:0030003 cellular cation homeostasis ( ); GO:0009987 cellular process ( ); GO:0019883 antigen processing and presentation of endogenous antigen ( ); GO:0042573 retinoic acid metabolic process ( ); GO:0008199 ferric iron binding ( ); GO:0055080 cation homeostasis ( ); GO:0016045 detection of bacterium ( ); GO:0045058 T cell selection ( ); GO:0001523 retinoid metabolic process ( ); GO:0016101 diterpenoid metabolic process ( ); GO:0006873 cellular ion homeostasis ( ); GO:0006721 terpenoid metabolic process ( ); GO:0009595 detection of biotic stimulus ( ); GO:0055082 cellular chemical homeostasis ( ); GO:0050801 ion homeostasis ( ); GO:0006776 vitamin A metabolic process ( ); GO:0032496 response to lipopolysaccharide ( ); ----------------GO-------------- GO:0009617 response to bacterium ( 2.13602087383114e-05 ); GO:0051707 response to other organism ( 0.000129913365619053 ); GO:0009607 response to biotic stimulus ( 0.000369383359334571 ); GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib ( 0.000502689388227062 ); GO:0030882 lipid antigen binding ( 0.000502689388227062 ); GO:0030884 exogenous lipid antigen binding ( 0.000502689388227062 ); GO:0002475 antigen processing and presentation via MHC class Ib ( 0.001005151338062 ); GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib ( 0.001005151338062 ); GO:0004947 bradykinin receptor activity ( 0.001005151338062 ); GO:0030881 beta-2-microglobulin binding ( 0.001005151338062 ); GO:0042574 retinal metabolic process ( 0.00150738594097877 ); GO:0043288 apocarotenoid metabolic process ( 0.00150738594097877 ); GO:0001758 retinal dehydrogenase activity ( 0.00150738594097877 ); GO:0004064 arylesterase activity ( 0.00150738594097877 ); GO:0051704 multi-organism process ( 0.00183752097955212 ); GO:0030005 cellular di-, tri-valent inorganic cation homeostasis ( 0.0028070905705681 ); GO:0055066 di-, tri-valent inorganic cation homeostasis ( 0.00305155066521582 ); GO:0030003 cellular cation homeostasis ( 0.00353127000677185 ); GO:0009987 cellular process ( 0.00370766743707925 ); GO:0019883 antigen processing and presentation of endogenous antigen ( 0.00401515195112467 ); GO:0042573 retinoic acid metabolic process ( 0.00401515195112467 ); GO:0008199 ferric iron binding ( 0.00401515195112467 ); GO:0055080 cation homeostasis ( 0.0045036725495511 ); GO:0016045 detection of bacterium ( 0.00451602439168231 ); GO:0045058 T cell selection ( 0.00601728183317907 ); GO:0001523 retinoid metabolic process ( 0.00651724799090048 ); GO:0016101 diterpenoid metabolic process ( 0.00651724799090048 ); GO:0006873 cellular ion homeostasis ( 0.00741376804717744 ); GO:0006721 terpenoid metabolic process ( 0.00751650136894844 ); GO:0009595 detection of biotic stimulus ( 0.00751650136894844 ); GO:0055082 cellular chemical homeostasis ( 0.00768638940380998 ); GO:0050801 ion homeostasis ( 0.00888074183166094 ); GO:0006776 vitamin A metabolic process ( 0.00951229492480987 ); GO:0032496 response to lipopolysaccharide ( 0.00951229492480987 ); ----------------KEGG-------------- hsa00363 Bisphenol A degradation ( 0.00251117347179275 ); hsa00361 gamma-Hexachlorocyclohexane degradation ( 0.00901368545837389 ); hsa04610 Complement and coagulation cascades ( 0.0336693319314011 ); hsa04640 Hematopoietic cell lineage ( 0.0414417125571345 ); ----------------CARTA-------------- ( 0.00901368545837389 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2918 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- SOLUBLE_FRACTION ( 0.0026717815268193 ); 3__5__CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY ( 0.00651724799090048 ); INSOLUBLE_FRACTION ( 0.00701698780579418 ); CIRCADIAN_RHYTHM ( 0.00701698780579418 ); CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY ( 0.00701698780579418 ); ----------------GOSLIM-------------- GO:0005578 proteinaceous extracellular matrix ( 0.00996710393881127 ); GO:0031012 extracellular matrix ( 0.00996710393881127 ); GO:0044421 extracellular region part ( 0.00996710393881127 ); GO:0018277 protein amino acid deamination ( 0.00996710393881127 ); GO:0008502 melatonin receptor activity ( 0.00996710393881127 ); GO:0007617 mating behavior ( 0.00996710393881127 ); GO:0004720 protein-lysine 6-oxidase activity ( 0.00996710393881127 ); GO:0019098 reproductive behavior ( 0.00996710393881127 ); GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity ( 0.00996710393881127 ); GO:0005625 soluble fraction ( 0.00996710393881127 ); GO:0007618 mating ( 0.00996710393881127 ); GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor ( 0.00996710393881127 ); GO:0051705 behavioral interaction between organisms ( 0.00996710393881127 ); GO:0033017 sarcoplasmic reticulum membrane ( 0.00996710393881127 ); GO:0005576 extracellular region ( 0.00996710393881127 ); GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors ( 0.00996710393881127 ); ----------------GO-------------- GO:0005578 proteinaceous extracellular matrix ( 0.000341054977601057 ); GO:0031012 extracellular matrix ( 0.000391600807693954 ); GO:0044421 extracellular region part ( 0.000421720628807723 ); GO:0018277 protein amino acid deamination ( 0.000502689388227062 ); GO:0008502 melatonin receptor activity ( 0.00150738594097877 ); GO:0007617 mating behavior ( 0.0020093932884192 ); GO:0004720 protein-lysine 6-oxidase activity ( 0.00251117347179275 ); GO:0019098 reproductive behavior ( 0.00301272658247664 ); GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity ( 0.00351405271181648 ); GO:0005625 soluble fraction ( 0.00416713389981162 ); GO:0007618 mating ( 0.00501667012473783 ); GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor ( 0.00701698780579418 ); GO:0051705 behavioral interaction between organisms ( 0.00801578877141895 ); GO:0033017 sarcoplasmic reticulum membrane ( 0.00801578877141895 ); GO:0005576 extracellular region ( 0.0084129957404383 ); GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors ( 0.00901368545837389 ); ----------------KEGG-------------- ( 0.0414417125571345 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2969 ========================= ----------------C2-------------- BIOCARTA_SODD_PATHWAY ( 0.00501667012473783 ); REACTOME_VIRAL_DSRNA_TLR3_TRIF_COMPLEX_ACTIVATES_RIP1 ( 0.00601728183317907 ); REACTOME_DEATH_RECEPTOR_SIGNALLING ( 0.00651724799090048 ); BIOCARTA_RELA_PATHWAY ( 0.00801578877141895 ); BIOCARTA_TNFR2_PATHWAY ( 0.00901368545837389 ); ----------------C3-------------- ( 0.00601728183317907 ); ----------------C4-------------- ( 0.00501667012473783 ); ----------------C5-------------- PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY ( 0.00425011158058009 ); REGULATION_OF_SIGNAL_TRANSDUCTION ( 0.00480823009452205 ); STRIATED_MUSCLE_CONTRACTION_GO_0006941 ( 0.00701698780579418 ); PROTEIN_KINASE_ACTIVITY ( 0.0080195255907171 ); REGULATION_OF_ACTION_POTENTIAL ( 0.00851485010423025 ); REGULATION_OF_MUSCLE_CONTRACTION ( 0.00951229492480987 ); ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CELL_POLARITY ( 0.00951229492480987 ); TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY ( 0.00951229492480987 ); ----------------GOSLIM-------------- GO:0006880 intracellular sequestering of iron ion ( ); GO:0030688 preribosome, small subunit precursor ( ); GO:0030684 preribosome ( ); GO:0005246 calcium channel regulator activity ( ); GO:0006942 regulation of striated muscle contraction ( ); GO:0051238 sequestering of metal ion ( ); GO:0005001 transmembrane receptor protein tyrosine phosphatase activity ( ); GO:0019198 transmembrane receptor protein phosphatase activity ( ); ----------------GO-------------- GO:0006880 intracellular sequestering of iron ion ( 0.001005151338062 ); GO:0030688 preribosome, small subunit precursor ( 0.001005151338062 ); GO:0030684 preribosome ( 0.00351405271181648 ); GO:0005246 calcium channel regulator activity ( 0.00651724799090048 ); GO:0006942 regulation of striated muscle contraction ( 0.00751650136894844 ); GO:0051238 sequestering of metal ion ( 0.00801578877141895 ); GO:0005001 transmembrane receptor protein tyrosine phosphatase activity ( 0.00851485010423025 ); GO:0019198 transmembrane receptor protein phosphatase activity ( 0.00851485010423025 ); ----------------KEGG-------------- hsa04210 Apoptosis ( 0.0433759952868593 ); hsa04620 Toll-like receptor signaling pathway ( 0.049157784602721 ); ----------------CARTA-------------- ptc1pathway ( 0.00451602439168231 ); pkcpathway ( 0.00551708924150862 ); il22bppathway ( 0.0100106785944665 ); hdacpathway ( 0.0115044757315573 ); pgc1apathway ( 0.0120019571227341 ); gpcrpathway ( 0.0154780223465801 ); keratinocytepathway ( 0.0169643921512707 ); fmlppathway ( 0.0204247372946039 ); metpathway ( 0.0219043834836399 ); tcrpathway ( 0.0223971516918701 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 0.0411113824630763 ); hnRNPC_iCLIP_(Koenig_2010) ( 0.0475781481744838 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2986 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00401515195112467 ); ----------------C4-------------- ( ); ----------------C5-------------- TRANSCRIPTION ( 0.00498063077010971 ); ATP_DEPENDENT_DNA_HELICASE_ACTIVITY ( 0.00551708924150862 ); ----------------GOSLIM-------------- GO:0034961 cellular biopolymer biosynthetic process ( 0.000132314164007824 ); GO:0043284 biopolymer biosynthetic process ( 0.00205068009179608 ); GO:0034645 cellular macromolecule biosynthetic process ( 0.00354887637248796 ); GO:0009059 macromolecule biosynthetic process ( 0.00877886182673887 ); GO:0010467 gene expression ( 0.000132314164007824 ); GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00205068009179608 ); GO:0010032 meiotic chromosome condensation ( 0.00354887637248796 ); GO:0033313 meiotic cell cycle checkpoint ( 0.00877886182673887 ); GO:0033315 meiotic cell cycle DNA replication checkpoint ( 0.000132314164007824 ); GO:0042138 meiotic DNA double-strand break formation ( 0.00205068009179608 ); GO:0044249 cellular biosynthetic process ( 0.00354887637248796 ); GO:0051276 chromosome organization ( 0.00877886182673887 ); GO:0009058 biosynthetic process ( 0.000132314164007824 ); GO:0007066 female meiosis sister chromatid cohesion ( 0.00205068009179608 ); GO:0051177 meiotic sister chromatid cohesion ( 0.00354887637248796 ); GO:0034960 cellular biopolymer metabolic process ( 0.00877886182673887 ); GO:0043283 biopolymer metabolic process ( 0.000132314164007824 ); GO:0044260 cellular macromolecule metabolic process ( 0.00205068009179608 ); GO:0043170 macromolecule metabolic process ( 0.00354887637248796 ); GO:0007143 female meiosis ( 0.00877886182673887 ); GO:0045132 meiotic chromosome segregation ( 0.000132314164007824 ); GO:0051445 regulation of meiotic cell cycle ( 0.00205068009179608 ); GO:0000076 DNA replication checkpoint ( 0.00354887637248796 ); GO:0000737 DNA catabolic process, endonucleolytic ( 0.00877886182673887 ); GO:0032297 negative regulation of DNA replication initiation ( 0.000132314164007824 ); GO:0016568 chromatin modification ( 0.00205068009179608 ); GO:0007062 sister chromatid cohesion ( 0.00354887637248796 ); GO:0007129 synapsis ( 0.00877886182673887 ); GO:0070192 chromosome organization involved in meiosis ( 0.000132314164007824 ); GO:0034708 methyltransferase complex ( 0.00205068009179608 ); GO:0035097 histone methyltransferase complex ( 0.00354887637248796 ); GO:0006350 transcription ( 0.00877886182673887 ); GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.000132314164007824 ); GO:0044238 primary metabolic process ( 0.00205068009179608 ); GO:0010556 regulation of macromolecule biosynthetic process ( 0.00354887637248796 ); GO:0030174 regulation of DNA replication initiation ( 0.00877886182673887 ); GO:0031326 regulation of cellular biosynthetic process ( 0.000132314164007824 ); GO:0009889 regulation of biosynthetic process ( 0.00205068009179608 ); GO:0044237 cellular metabolic process ( 0.00354887637248796 ); GO:0048599 oocyte development ( 0.00877886182673887 ); GO:0009994 oocyte differentiation ( 0.000132314164007824 ); GO:0006400 tRNA modification ( 0.00205068009179608 ); GO:0016070 RNA metabolic process ( 0.00354887637248796 ); GO:0046620 regulation of organ growth ( 0.00877886182673887 ); GO:0031323 regulation of cellular metabolic process ( 0.000132314164007824 ); GO:0060255 regulation of macromolecule metabolic process ( 0.00205068009179608 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00354887637248796 ); GO:0008152 metabolic process ( 0.00877886182673887 ); GO:0001541 ovarian follicle development ( 0.000132314164007824 ); GO:0035265 organ growth ( 0.00205068009179608 ); GO:0019222 regulation of metabolic process ( 0.00354887637248796 ); GO:0019843 rRNA binding ( 0.00877886182673887 ); ----------------GO-------------- GO:0034961 cellular biopolymer biosynthetic process ( 0.000128984692567923 ); GO:0043284 biopolymer biosynthetic process ( 0.000128984692567923 ); GO:0034645 cellular macromolecule biosynthetic process ( 0.000196015961006136 ); GO:0009059 macromolecule biosynthetic process ( 0.000202159885182689 ); GO:0010467 gene expression ( 0.0002449161385494 ); GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.000473618613704415 ); GO:0010032 meiotic chromosome condensation ( 0.000502689388227062 ); GO:0033313 meiotic cell cycle checkpoint ( 0.000502689388227062 ); GO:0033315 meiotic cell cycle DNA replication checkpoint ( 0.000502689388227062 ); GO:0042138 meiotic DNA double-strand break formation ( 0.000502689388227062 ); GO:0044249 cellular biosynthetic process ( 0.00057799635810648 ); GO:0051276 chromosome organization ( 0.000636523036233357 ); GO:0009058 biosynthetic process ( 0.000658733151147951 ); GO:0007066 female meiosis sister chromatid cohesion ( 0.001005151338062 ); GO:0051177 meiotic sister chromatid cohesion ( 0.001005151338062 ); GO:0034960 cellular biopolymer metabolic process ( 0.0010427090601465 ); GO:0043283 biopolymer metabolic process ( 0.00108411060332551 ); GO:0044260 cellular macromolecule metabolic process ( 0.00118464654286601 ); GO:0043170 macromolecule metabolic process ( 0.00130604544640635 ); GO:0007143 female meiosis ( 0.00251117347179275 ); GO:0045132 meiotic chromosome segregation ( 0.00301272658247664 ); GO:0051445 regulation of meiotic cell cycle ( 0.00301272658247664 ); GO:0000076 DNA replication checkpoint ( 0.00351405271181648 ); GO:0000737 DNA catabolic process, endonucleolytic ( 0.00351405271181648 ); GO:0032297 negative regulation of DNA replication initiation ( 0.00351405271181648 ); GO:0016568 chromatin modification ( 0.00392284723071534 ); GO:0007062 sister chromatid cohesion ( 0.00401515195112467 ); GO:0007129 synapsis ( 0.00401515195112467 ); GO:0070192 chromosome organization involved in meiosis ( 0.00401515195112467 ); GO:0034708 methyltransferase complex ( 0.00401515195112467 ); GO:0035097 histone methyltransferase complex ( 0.00401515195112467 ); GO:0006350 transcription ( 0.00408518379500557 ); GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00416008056982227 ); GO:0044238 primary metabolic process ( 0.00440655854761667 ); GO:0010556 regulation of macromolecule biosynthetic process ( 0.00442237973306574 ); GO:0030174 regulation of DNA replication initiation ( 0.00451602439168231 ); GO:0031326 regulation of cellular biosynthetic process ( 0.00510534049148098 ); GO:0009889 regulation of biosynthetic process ( 0.00519366577821032 ); GO:0044237 cellular metabolic process ( 0.00526827647939627 ); GO:0048599 oocyte development ( 0.00551708924150862 ); GO:0009994 oocyte differentiation ( 0.00601728183317907 ); GO:0006400 tRNA modification ( 0.00651724799090048 ); GO:0016070 RNA metabolic process ( 0.00695121354123317 ); GO:0046620 regulation of organ growth ( 0.00701698780579418 ); GO:0031323 regulation of cellular metabolic process ( 0.00756501456353287 ); GO:0060255 regulation of macromolecule metabolic process ( 0.00762378595927702 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00796355038137038 ); GO:0008152 metabolic process ( 0.00893020869558775 ); GO:0001541 ovarian follicle development ( 0.00901368545837389 ); GO:0035265 organ growth ( 0.00901368545837389 ); GO:0019222 regulation of metabolic process ( 0.00935388946222827 ); GO:0019843 rRNA binding ( 0.00951229492480987 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.00551708924150862 ); ----------------RBP-------------- AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0100880574420406 ); hnRNPC_iCLIP_(Koenig_2010) ( 0.0475781481744838 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2988 ========================= ----------------C2-------------- KEGG_CALCIUM_SIGNALING_PATHWAY ( 0.00338011858197418 ); KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS ( 0.00551708924150862 ); ----------------C3-------------- CTCCAAG,MIR-432 ( 0.000450954530599726 ); CGGTGTG,MIR-220 ( 0.00301272658247664 ); V$EVI1_06 ( 0.00951229492480987 ); ----------------C4-------------- ( ); ----------------C5-------------- 3__5__CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY ( 0.00651724799090048 ); CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY ( 0.00701698780579418 ); ----------------GOSLIM-------------- GO:0007343 egg activation ( ); GO:0033011 perinuclear theca ( ); GO:0035039 male pronucleus formation ( ); GO:0009416 response to light stimulus ( ); GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity ( ); GO:0004738 pyruvate dehydrogenase activity ( ); GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity ( ); GO:0009314 response to radiation ( ); GO:0004691 cAMP-dependent protein kinase activity ( ); GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor ( ); GO:0004690 cyclic nucleotide-dependent protein kinase activity ( ); GO:0009628 response to abiotic stimulus ( ); GO:0005452 inorganic anion exchanger activity ( ); GO:0050699 WW domain binding ( ); GO:0030552 cAMP binding ( ); GO:0008542 visual learning ( ); GO:0015380 anion exchanger activity ( ); GO:0007632 visual behavior ( ); GO:0015106 bicarbonate transmembrane transporter activity ( ); GO:0015108 chloride transmembrane transporter activity ( ); GO:0016208 AMP binding ( ); GO:0015301 anion:anion antiporter activity ( ); ----------------GO-------------- GO:0007343 egg activation ( 0.000502689388227062 ); GO:0033011 perinuclear theca ( 0.000502689388227062 ); GO:0035039 male pronucleus formation ( 0.001005151338062 ); GO:0009416 response to light stimulus ( 0.00118528503262949 ); GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity ( 0.00150738594097877 ); GO:0004738 pyruvate dehydrogenase activity ( 0.00150738594097877 ); GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity ( 0.00150738594097877 ); GO:0009314 response to radiation ( 0.00189904412641522 ); GO:0004691 cAMP-dependent protein kinase activity ( 0.00351405271181648 ); GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor ( 0.00351405271181648 ); GO:0004690 cyclic nucleotide-dependent protein kinase activity ( 0.00451602439168231 ); GO:0009628 response to abiotic stimulus ( 0.00558670611806421 ); GO:0005452 inorganic anion exchanger activity ( 0.00651724799090048 ); GO:0050699 WW domain binding ( 0.00651724799090048 ); GO:0030552 cAMP binding ( 0.00701698780579418 ); GO:0008542 visual learning ( 0.00801578877141895 ); GO:0015380 anion exchanger activity ( 0.00851485010423025 ); GO:0007632 visual behavior ( 0.00901368545837389 ); GO:0015106 bicarbonate transmembrane transporter activity ( 0.00901368545837389 ); GO:0015108 chloride transmembrane transporter activity ( 0.00901368545837389 ); GO:0016208 AMP binding ( 0.00901368545837389 ); GO:0015301 anion:anion antiporter activity ( 0.00951229492480987 ); ----------------KEGG-------------- hsa04020 Calcium signaling pathway ( 0.00341761181540652 ); hsa00290 Valine, leucine and isoleucine biosynthesis ( 0.00551708924150862 ); hsa04740 Olfactory transduction ( 0.0145767455140234 ); hsa00020 Citrate cycle (TCA cycle) ( 0.0154780223465801 ); hsa00650 Butanoate metabolism ( 0.0189430768653164 ); hsa00620 Pyruvate metabolism ( 0.0209181763751527 ); hsa04742 Taste transduction ( 0.0243659909866273 ); hsa00310 Lysine degradation ( 0.0248576428758699 ); hsa04340 Hedgehog signaling pathway ( 0.028292967305334 ); hsa05110 Vibrio cholerae infection ( 0.0287828377594047 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.0307400977173022 ); hsa04720 Long-term potentiation ( 0.0351309591964324 ); hsa04210 Apoptosis ( 0.0433759952868593 ); hsa04540 Gap junction ( 0.047234025639284 ); hsa04912 GnRH signaling pathway ( 0.0486771728885087 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.00851485010423025 ); ============================ group3058 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_110 ( 0.00751650136894844 ); module_133 ( 0.00751650136894844 ); module_160 ( 0.00751650136894844 ); module_35 ( 0.00801578877141895 ); ----------------C5-------------- ( 0.00701698780579418 ); ----------------GOSLIM-------------- GO:0004816 asparagine-tRNA ligase activity ( 0.000929747697235133 ); GO:0006421 asparaginyl-tRNA aminoacylation ( 0.000929747697235133 ); GO:0006422 aspartyl-tRNA aminoacylation ( 0.000929747697235133 ); GO:0004815 aspartate-tRNA ligase activity ( 0.000929747697235133 ); GO:0003676 nucleic acid binding ( 0.000929747697235133 ); ----------------GO-------------- GO:0004816 asparagine-tRNA ligase activity ( 0.000502689388227062 ); GO:0006421 asparaginyl-tRNA aminoacylation ( 0.001005151338062 ); GO:0006422 aspartyl-tRNA aminoacylation ( 0.00150738594097877 ); GO:0004815 aspartate-tRNA ligase activity ( 0.0020093932884192 ); GO:0003676 nucleic acid binding ( 0.00977095045953154 ); ----------------KEGG-------------- hsa00252 Alanine and aspartate metabolism ( 0.0139896301684387 ); hsa00970 Aminoacyl-tRNA biosynthesis ( 0.0204247372946039 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0411113824630763 ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_C2 ( 0.0154780223465801 ); ARE_ALL ( 0.0371575614350308 ); ============================ group3092 ========================= ----------------C2-------------- ( 0.00801578877141895 ); ----------------C3-------------- TCANNTGAY_V$SREBP1_01 ( 0.000611036054440016 ); V$SREBP1_01 ( 0.00192751994624104 ); V$USF_02 ( 0.00408492973498161 ); TGANTCA_V$AP1_C ( 0.00734788118925768 ); ----------------C4-------------- module_110 ( 0.00751650136894844 ); module_133 ( 0.00751650136894844 ); module_150 ( 0.00751650136894844 ); module_160 ( 0.00751650136894844 ); module_35 ( 0.00801578877141895 ); module_474 ( 0.00801578877141895 ); module_388 ( 0.00851485010423025 ); ----------------C5-------------- RNA_PROCESSING ( 0.00257239960031737 ); TRNA_PROCESSING ( 0.00501667012473783 ); LIGASE_ACTIVITY__FORMING_CARBON_OXYGEN_BONDS ( 0.00701698780579418 ); AEROBIC_RESPIRATION ( 0.00751650136894844 ); TRNA_METABOLIC_PROCESS ( 0.00901368545837389 ); CELLULAR_RESPIRATION ( 0.00951229492480987 ); ----------------GOSLIM-------------- GO:0006434 seryl-tRNA aminoacylation ( ); GO:0004828 serine-tRNA ligase activity ( ); GO:0046627 negative regulation of insulin receptor signaling pathway ( ); GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity ( ); GO:0046626 regulation of insulin receptor signaling pathway ( ); GO:0016307 phosphatidylinositol phosphate kinase activity ( ); GO:0046488 phosphatidylinositol metabolic process ( ); ----------------GO-------------- GO:0006434 seryl-tRNA aminoacylation ( 0.0020093932884192 ); GO:0004828 serine-tRNA ligase activity ( 0.0020093932884192 ); GO:0046627 negative regulation of insulin receptor signaling pathway ( 0.00301272658247664 ); GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity ( 0.00301272658247664 ); GO:0046626 regulation of insulin receptor signaling pathway ( 0.00351405271181648 ); GO:0016307 phosphatidylinositol phosphate kinase activity ( 0.00501667012473783 ); GO:0046488 phosphatidylinositol metabolic process ( 0.00801578877141895 ); ----------------KEGG-------------- hsa00260 Glycine, serine and threonine metabolism ( 0.0204247372946039 ); hsa00970 Aminoacyl-tRNA biosynthesis ( 0.0204247372946039 ); hsa04930 Type II diabetes mellitus ( 0.0204247372946039 ); hsa00562 Inositol phosphate metabolism ( 0.0238741160135927 ); hsa04920 Adipocytokine signaling pathway ( 0.0326938070017745 ); hsa04070 Phosphatidylinositol signaling system ( 0.037562583578607 ); ----------------CARTA-------------- tidpathway ( 0.00301272658247664 ); arfpathway ( 0.00351405271181648 ); p53hypoxiapathway ( 0.00551708924150862 ); il6pathway ( 0.00701698780579418 ); ----------------RBP-------------- TIAL1_iCLIP_(Wang_2010) ( 0.000184167775158538 ); ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 0.000611647391678563 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.00685212636775637 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00796580405185616 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00985986361567313 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0116068157678167 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0141631088708994 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0289448316912641 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3129 ========================= ----------------C2-------------- BIOCARTA_CELL2CELL_PATHWAY ( 0.00701698780579418 ); REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS ( 0.00751650136894844 ); KEGG_RIBOFLAVIN_METABOLISM ( 0.00801578877141895 ); BIOCARTA_PTEN_PATHWAY ( 0.00901368545837389 ); ----------------C3-------------- ( 0.00396307671590615 ); ----------------C4-------------- module_26 ( 0.00341761181540652 ); module_389 ( 0.00353127000677185 ); module_207 ( 0.00404411813318692 ); ----------------C5-------------- POSITIVE_REGULATION_OF_CELL_MIGRATION ( 0.00501667012473783 ); PROTEIN_PHOSPHATASE_BINDING ( 0.00501667012473783 ); FOCAL_ADHESION ( 0.00551708924150862 ); PHOSPHATASE_BINDING ( 0.00651724799090048 ); CELL_SUBSTRATE_ADHERENS_JUNCTION ( 0.00701698780579418 ); CELL_MATRIX_JUNCTION ( 0.00801578877141895 ); THIOLESTER_HYDROLASE_ACTIVITY ( 0.00801578877141895 ); ACTIVATION_OF_IMMUNE_RESPONSE ( 0.00851485010423025 ); INSULIN_RECEPTOR_SIGNALING_PATHWAY ( 0.00901368545837389 ); ----------------GOSLIM-------------- GO:0004416 hydroxyacylglutathione hydrolase activity ( 0.00201417138307129 ); GO:0033819 lipoyl(octanoyl) transferase activity ( 0.00201417138307129 ); GO:0000273 lipoic acid metabolic process ( 0.00201417138307129 ); GO:0009105 lipoic acid biosynthetic process ( 0.00201417138307129 ); GO:0009106 lipoate metabolic process ( 0.00201417138307129 ); GO:0009107 lipoate biosynthetic process ( 0.00201417138307129 ); GO:0050853 B cell receptor signaling pathway ( 0.00201417138307129 ); GO:0003993 acid phosphatase activity ( 0.00201417138307129 ); GO:0050852 T cell receptor signaling pathway ( 0.00201417138307129 ); ----------------GO-------------- GO:0004416 hydroxyacylglutathione hydrolase activity ( 0.000502689388227062 ); GO:0033819 lipoyl(octanoyl) transferase activity ( 0.000502689388227062 ); GO:0000273 lipoic acid metabolic process ( 0.001005151338062 ); GO:0009105 lipoic acid biosynthetic process ( 0.001005151338062 ); GO:0009106 lipoate metabolic process ( 0.001005151338062 ); GO:0009107 lipoate biosynthetic process ( 0.001005151338062 ); GO:0050853 B cell receptor signaling pathway ( 0.00351405271181648 ); GO:0003993 acid phosphatase activity ( 0.00501667012473783 ); GO:0050852 T cell receptor signaling pathway ( 0.00701698780579418 ); ----------------KEGG-------------- hsa00740 Riboflavin metabolism ( 0.00751650136894844 ); hsa00361 gamma-Hexachlorocyclohexane degradation ( 0.00901368545837389 ); hsa00620 Pyruvate metabolism ( 0.0209181763751527 ); ----------------CARTA-------------- ( 0.0110067689069923 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3131 ========================= ----------------C2-------------- REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS ( 3.46490837896554e-05 ); REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS ( 9.16737852100385e-05 ); REACTOME_GLUCOSE_AND_OTHER_SUGAR_SLC_TRANSPORTERS ( 0.000739288910951873 ); REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT ( 0.00308726765851081 ); REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES ( 0.0050315019893465 ); REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_FREE_FATTY_ACIDS ( 0.00951229492480987 ); ----------------C3-------------- TTTNNANAGCYR_UNKNOWN ( 0.00149651625819007 ); V$HIF1_Q5 ( 0.00338011858197418 ); V$NFAT_Q4_01 ( 0.00441838222092029 ); ----------------C4-------------- module_415 ( 0.00651724799090048 ); module_368 ( 0.00901368545837389 ); module_162 ( 0.00951229492480987 ); ----------------C5-------------- SYNAPTIC_TRANSMISSION ( 0.00315929556246113 ); TRANSMISSION_OF_NERVE_IMPULSE ( 0.00372461865321076 ); PHOSPHOLIPASE_C_ACTIVATION ( 0.00551708924150862 ); NEUTRAL_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00601728183317907 ); SOLUTE_SODIUM_SYMPORTER_ACTIVITY ( 0.00651724799090048 ); INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHODIESTERASE_ACTIVITY ( 0.00651724799090048 ); PHOSPHOLIPASE_C_ACTIVITY ( 0.00751650136894844 ); ----------------GOSLIM-------------- GO:0005283 sodium:amino acid symporter activity ( 0.000601439452945602 ); GO:0005416 cation:amino acid symporter activity ( 0.00283416905601961 ); GO:0005328 neurotransmitter:sodium symporter activity ( 0.000601439452945602 ); GO:0005326 neurotransmitter transporter activity ( 0.00283416905601961 ); GO:0005343 organic acid:sodium symporter activity ( 0.000601439452945602 ); GO:0015370 solute:sodium symporter activity ( 0.00283416905601961 ); GO:0015171 amino acid transmembrane transporter activity ( 0.000601439452945602 ); GO:0005275 amine transmembrane transporter activity ( 0.00283416905601961 ); GO:0006361 transcription initiation from RNA polymerase I promoter ( 0.000601439452945602 ); GO:0003716 RNA polymerase I transcription termination factor activity ( 0.00283416905601961 ); GO:0042134 rRNA primary transcript binding ( 0.000601439452945602 ); GO:0046943 carboxylic acid transmembrane transporter activity ( 0.00283416905601961 ); GO:0005342 organic acid transmembrane transporter activity ( 0.000601439452945602 ); GO:0006836 neurotransmitter transport ( 0.00283416905601961 ); GO:0015375 glycine:sodium symporter activity ( 0.000601439452945602 ); GO:0015294 solute:cation symporter activity ( 0.00283416905601961 ); GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity ( 0.000601439452945602 ); GO:0002080 acrosomal membrane ( 0.00283416905601961 ); GO:0003715 transcription termination factor activity ( 0.000601439452945602 ); GO:0005332 gamma-aminobutyric acid:sodium symporter activity ( 0.00283416905601961 ); GO:0015293 symporter activity ( 0.000601439452945602 ); GO:0065004 protein-DNA complex assembly ( 0.00283416905601961 ); GO:0015185 L-gamma-aminobutyric acid transmembrane transporter activity ( 0.000601439452945602 ); GO:0015187 glycine transmembrane transporter activity ( 0.00283416905601961 ); GO:0006353 transcription termination ( 0.000601439452945602 ); GO:0006360 transcription from RNA polymerase I promoter ( 0.00283416905601961 ); GO:0015291 secondary active transmembrane transporter activity ( 0.000601439452945602 ); GO:0007268 synaptic transmission ( 0.00283416905601961 ); GO:0015175 neutral amino acid transmembrane transporter activity ( 0.000601439452945602 ); GO:0030667 secretory granule membrane ( 0.00283416905601961 ); GO:0019843 rRNA binding ( 0.000601439452945602 ); GO:0019226 transmission of nerve impulse ( 0.00283416905601961 ); ----------------GO-------------- GO:0005283 sodium:amino acid symporter activity ( 6.35803665924767e-06 ); GO:0005416 cation:amino acid symporter activity ( 1.24789570305629e-05 ); GO:0005328 neurotransmitter:sodium symporter activity ( 3.87150625253163e-05 ); GO:0005326 neurotransmitter transporter activity ( 5.22572344283188e-05 ); GO:0005343 organic acid:sodium symporter activity ( 5.22572344283188e-05 ); GO:0015370 solute:sodium symporter activity ( 0.000222582321505622 ); GO:0015171 amino acid transmembrane transporter activity ( 0.000264117307950331 ); GO:0005275 amine transmembrane transporter activity ( 0.000396352364509227 ); GO:0006361 transcription initiation from RNA polymerase I promoter ( 0.000502689388227062 ); GO:0003716 RNA polymerase I transcription termination factor activity ( 0.000502689388227062 ); GO:0042134 rRNA primary transcript binding ( 0.000502689388227062 ); GO:0046943 carboxylic acid transmembrane transporter activity ( 0.000618904707712757 ); GO:0005342 organic acid transmembrane transporter activity ( 0.000635461381502082 ); GO:0006836 neurotransmitter transport ( 0.000686414595956196 ); GO:0015375 glycine:sodium symporter activity ( 0.001005151338062 ); GO:0015294 solute:cation symporter activity ( 0.00114053022309259 ); GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity ( 0.00150738594097877 ); GO:0002080 acrosomal membrane ( 0.0020093932884192 ); GO:0003715 transcription termination factor activity ( 0.0020093932884192 ); GO:0005332 gamma-aminobutyric acid:sodium symporter activity ( 0.0020093932884192 ); GO:0015293 symporter activity ( 0.00237905510057815 ); GO:0065004 protein-DNA complex assembly ( 0.00247482260572562 ); GO:0015185 L-gamma-aminobutyric acid transmembrane transporter activity ( 0.00251117347179275 ); GO:0015187 glycine transmembrane transporter activity ( 0.00251117347179275 ); GO:0006353 transcription termination ( 0.00351405271181648 ); GO:0006360 transcription from RNA polymerase I promoter ( 0.00451602439168231 ); GO:0015291 secondary active transmembrane transporter activity ( 0.00476414781354874 ); GO:0007268 synaptic transmission ( 0.00725238249565972 ); GO:0015175 neutral amino acid transmembrane transporter activity ( 0.00851485010423025 ); GO:0030667 secretory granule membrane ( 0.00951229492480987 ); GO:0019843 rRNA binding ( 0.00951229492480987 ); GO:0019226 transmission of nerve impulse ( 0.00953782417892728 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.0238741160135927 ); hsa04742 Taste transduction ( 0.0243659909866273 ); hsa04720 Long-term potentiation ( 0.0351309591964324 ); hsa04730 Long-term depression ( 0.0365905964493483 ); hsa04070 Phosphatidylinositol signaling system ( 0.037562583578607 ); hsa04540 Gap junction ( 0.047234025639284 ); hsa04912 GnRH signaling pathway ( 0.0486771728885087 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3137 ========================= ----------------C2-------------- REACTOME_APOPTOSIS ( 3.02119729449852e-05 ); REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS ( 0.00154751022767586 ); REACTOME_HIV_INFECTION ( 0.00356954834639119 ); KEGG_TAURINE_AND_HYPOTAURINE_METABOLISM ( 0.00501667012473783 ); BIOCARTA_SODD_PATHWAY ( 0.00501667012473783 ); REACTOME_DEATH_RECEPTOR_SIGNALLING ( 0.00651724799090048 ); BIOCARTA_RELA_PATHWAY ( 0.00801578877141895 ); ----------------C3-------------- V$TEL2_Q6 ( 0.00260532658601276 ); SCGGAAGY_V$ELK1_02 ( 0.00586011520679115 ); ----------------C4-------------- module_377 ( 0.00501667012473783 ); module_54 ( 0.00616900416445281 ); MORF_RAN ( 0.00636907611868136 ); module_431 ( 0.00751650136894844 ); module_311 ( 0.00901368545837389 ); module_151 ( 0.0092964023800455 ); ----------------C5-------------- POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS ( 0.00485250329261952 ); NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_AND_NUCLEIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00501667012473783 ); PROTEOGLYCAN_METABOLIC_PROCESS ( 0.00951229492480987 ); ----------------GOSLIM-------------- GO:0016250 N-sulfoglucosamine sulfohydrolase activity ( 0.00320004589459822 ); GO:0016826 hydrolase activity, acting on acid sulfur-nitrogen bonds ( 0.00320004589459822 ); GO:0015207 adenine transmembrane transporter activity ( 0.00320004589459822 ); GO:0005345 purine transmembrane transporter activity ( 0.00320004589459822 ); GO:0003840 gamma-glutamyltransferase activity ( 0.00320004589459822 ); GO:0015205 nucleobase transmembrane transporter activity ( 0.00320004589459822 ); GO:0005123 death receptor binding ( 0.00320004589459822 ); GO:0006750 glutathione biosynthetic process ( 0.00320004589459822 ); GO:0005838 proteasome regulatory particle ( 0.00320004589459822 ); GO:0006917 induction of apoptosis ( 0.00320004589459822 ); GO:0012502 induction of programmed cell death ( 0.00320004589459822 ); GO:0000299 integral to membrane of membrane fraction ( 0.00320004589459822 ); GO:0022624 proteasome accessory complex ( 0.00320004589459822 ); GO:0008625 induction of apoptosis via death domain receptors ( 0.00320004589459822 ); GO:0044419 interspecies interaction between organisms ( 0.00320004589459822 ); GO:0015932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity ( 0.00320004589459822 ); GO:0006915 apoptosis ( 0.00320004589459822 ); GO:0012501 programmed cell death ( 0.00320004589459822 ); GO:0044444 cytoplasmic part ( 0.00320004589459822 ); GO:0033116 ER-Golgi intermediate compartment membrane ( 0.00320004589459822 ); GO:0043065 positive regulation of apoptosis ( 0.00320004589459822 ); GO:0043068 positive regulation of programmed cell death ( 0.00320004589459822 ); GO:0008484 sulfuric ester hydrolase activity ( 0.00320004589459822 ); GO:0016755 transferase activity, transferring amino-acyl groups ( 0.00320004589459822 ); GO:0008219 cell death ( 0.00320004589459822 ); GO:0016265 death ( 0.00320004589459822 ); GO:0005164 tumor necrosis factor receptor binding ( 0.00320004589459822 ); GO:0032813 tumor necrosis factor receptor superfamily binding ( 0.00320004589459822 ); ----------------GO-------------- GO:0016250 N-sulfoglucosamine sulfohydrolase activity ( 0.000502689388227062 ); GO:0016826 hydrolase activity, acting on acid sulfur-nitrogen bonds ( 0.000502689388227062 ); GO:0015207 adenine transmembrane transporter activity ( 0.001005151338062 ); GO:0005345 purine transmembrane transporter activity ( 0.0020093932884192 ); GO:0003840 gamma-glutamyltransferase activity ( 0.00301272658247664 ); GO:0015205 nucleobase transmembrane transporter activity ( 0.00301272658247664 ); GO:0005123 death receptor binding ( 0.00351405271181648 ); GO:0006750 glutathione biosynthetic process ( 0.00401515195112467 ); GO:0005838 proteasome regulatory particle ( 0.00401515195112467 ); GO:0006917 induction of apoptosis ( 0.00476414781354874 ); GO:0012502 induction of programmed cell death ( 0.00480823009452205 ); GO:0000299 integral to membrane of membrane fraction ( 0.00551708924150862 ); GO:0022624 proteasome accessory complex ( 0.00551708924150862 ); GO:0008625 induction of apoptosis via death domain receptors ( 0.00601728183317907 ); GO:0044419 interspecies interaction between organisms ( 0.00602090488400706 ); GO:0015932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity ( 0.00701698780579418 ); GO:0006915 apoptosis ( 0.00708556563161024 ); GO:0012501 programmed cell death ( 0.00727576371321194 ); GO:0044444 cytoplasmic part ( 0.00737911672129413 ); GO:0033116 ER-Golgi intermediate compartment membrane ( 0.00751650136894844 ); GO:0043065 positive regulation of apoptosis ( 0.00763150132922996 ); GO:0043068 positive regulation of programmed cell death ( 0.00779671014863192 ); GO:0008484 sulfuric ester hydrolase activity ( 0.00851485010423025 ); GO:0016755 transferase activity, transferring amino-acyl groups ( 0.00851485010423025 ); GO:0008219 cell death ( 0.00856127327602485 ); GO:0016265 death ( 0.00869417746766286 ); GO:0005164 tumor necrosis factor receptor binding ( 0.00901368545837389 ); GO:0032813 tumor necrosis factor receptor superfamily binding ( 0.00951229492480987 ); ----------------KEGG-------------- hsa00460 Cyanoamino acid metabolism ( 0.00451602439168231 ); hsa00430 Taurine and hypotaurine metabolism ( 0.00501667012473783 ); hsa00531 Glycosaminoglycan degradation ( 0.00901368545837389 ); hsa00450 Selenoamino acid metabolism ( 0.0124992131712907 ); hsa01032 Glycan structures - degradation ( 0.0154780223465801 ); hsa03050 Proteasome ( 0.0219043834836399 ); hsa00480 Glutathione metabolism ( 0.0248576428758699 ); hsa00590 Arachidonic acid metabolism ( 0.0268220213932411 ); hsa04210 Apoptosis ( 0.0433759952868593 ); hsa04620 Toll-like receptor signaling pathway ( 0.049157784602721 ); ----------------CARTA-------------- notchpathway ( 0.00351405271181648 ); hswisnfpathway ( 0.00501667012473783 ); huntingtonpathway ( 0.00601728183317907 ); il22bppathway ( 0.0100106785944665 ); hdacpathway ( 0.0115044757315573 ); gcrpathway ( 0.0124992131712907 ); ps1pathway ( 0.0129962439679628 ); metpathway ( 0.0219043834836399 ); ----------------RBP-------------- ( 0.0289448316912641 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3203 ========================= ----------------C2-------------- ( 0.00951229492480987 ); ----------------C3-------------- V$FOXO1_01 ( 0.00384297153364158 ); V$MYCMAX_02 ( 0.00416713389981162 ); AAAYWAACM_V$HFH4_01 ( 0.00416713389981162 ); CAGGTG_V$E12_Q6 ( 0.00907256723369292 ); ----------------C4-------------- module_12 ( 0.000571642019056033 ); module_11 ( 0.00181724829918333 ); module_100 ( 0.00183752097955212 ); module_137 ( 0.00184771080686117 ); module_66 ( 0.0019096016590512 ); ----------------C5-------------- NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS ( 0.00551708924150862 ); ACUTE_INFLAMMATORY_RESPONSE ( 0.00551708924150862 ); NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00751650136894844 ); GLUTATHIONE_TRANSFERASE_ACTIVITY ( 0.00751650136894844 ); NEGATIVE_REGULATION_OF_DNA_BINDING ( 0.00851485010423025 ); NEGATIVE_REGULATION_OF_BINDING ( 0.00901368545837389 ); ----------------GOSLIM-------------- GO:0019898 extrinsic to membrane ( ); GO:0045079 negative regulation of chemokine biosynthetic process ( ); GO:0001957 intramembranous ossification ( ); GO:0001960 negative regulation of cytokine-mediated signaling pathway ( ); GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway ( ); GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway ( ); GO:0001959 regulation of cytokine-mediated signaling pathway ( ); GO:0043009 chordate embryonic development ( ); GO:0009792 embryonic development ending in birth or egg hatching ( ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( ); GO:0045073 regulation of chemokine biosynthetic process ( ); GO:0042033 chemokine biosynthetic process ( ); GO:0045668 negative regulation of osteoblast differentiation ( ); GO:0050755 chemokine metabolic process ( ); GO:0030866 cortical actin cytoskeleton organization ( ); GO:0030865 cortical cytoskeleton organization ( ); GO:0032642 regulation of chemokine production ( ); GO:0032602 chemokine production ( ); GO:0042036 negative regulation of cytokine biosynthetic process ( ); ----------------GO-------------- GO:0019898 extrinsic to membrane ( 0.000450954530599726 ); GO:0045079 negative regulation of chemokine biosynthetic process ( 0.000502689388227062 ); GO:0001957 intramembranous ossification ( 0.001005151338062 ); GO:0001960 negative regulation of cytokine-mediated signaling pathway ( 0.001005151338062 ); GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway ( 0.001005151338062 ); GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway ( 0.001005151338062 ); GO:0001959 regulation of cytokine-mediated signaling pathway ( 0.00301272658247664 ); GO:0043009 chordate embryonic development ( 0.00364669244217413 ); GO:0009792 embryonic development ending in birth or egg hatching ( 0.0037638746372336 ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( 0.00401515195112467 ); GO:0045073 regulation of chemokine biosynthetic process ( 0.00401515195112467 ); GO:0042033 chemokine biosynthetic process ( 0.00451602439168231 ); GO:0045668 negative regulation of osteoblast differentiation ( 0.00451602439168231 ); GO:0050755 chemokine metabolic process ( 0.00451602439168231 ); GO:0030866 cortical actin cytoskeleton organization ( 0.00501667012473783 ); GO:0030865 cortical cytoskeleton organization ( 0.00551708924150862 ); GO:0032642 regulation of chemokine production ( 0.00601728183317907 ); GO:0032602 chemokine production ( 0.00651724799090048 ); GO:0042036 negative regulation of cytokine biosynthetic process ( 0.00751650136894844 ); ----------------KEGG-------------- hsa04930 Type II diabetes mellitus ( 0.0204247372946039 ); hsa04742 Taste transduction ( 0.0243659909866273 ); hsa00480 Glutathione metabolism ( 0.0248576428758699 ); hsa05213 Endometrial cancer ( 0.0258402777627074 ); hsa05217 Basal cell carcinoma ( 0.0273125592119858 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0307400977173022 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0317173958356051 ); hsa04920 Adipocytokine signaling pathway ( 0.0326938070017745 ); hsa05210 Colorectal cancer ( 0.0414417125571345 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3318 ========================= ----------------C2-------------- REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES ( 0.00501667012473783 ); KEGG_PHENYLALANINE_METABOLISM ( 0.00851485010423025 ); ----------------C3-------------- ( ); ----------------C4-------------- module_117 ( 0.000259235792659145 ); module_324 ( 0.00187077258710907 ); module_140 ( 0.00401515195112467 ); module_354 ( 0.00901368545837389 ); ----------------C5-------------- AMINO_ACID_AND_DERIVATIVE_METABOLIC_PROCESS ( 0.00105353529608842 ); AMINE_METABOLIC_PROCESS ( 0.00204346261966841 ); NITROGEN_COMPOUND_METABOLIC_PROCESS ( 0.00244269882435161 ); AMINE_BIOSYNTHETIC_PROCESS ( 0.00751650136894844 ); BIOGENIC_AMINE_METABOLIC_PROCESS ( 0.00801578877141895 ); ----------------GOSLIM-------------- GO:0018958 phenol metabolic process ( ); GO:0006576 biogenic amine metabolic process ( ); GO:0006571 tyrosine biosynthetic process ( ); GO:0009073 aromatic amino acid family biosynthetic process ( ); GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway ( ); GO:0018126 protein amino acid hydroxylation ( ); GO:0046417 chorismate metabolic process ( ); GO:0070173 regulation of enamel mineralization ( ); GO:0006575 amino acid derivative metabolic process ( ); GO:0070166 enamel mineralization ( ); GO:0070170 regulation of tooth mineralization ( ); GO:0001520 outer dense fiber ( ); GO:0030314 junctional membrane complex ( ); GO:0006725 cellular aromatic compound metabolic process ( ); GO:0034505 tooth mineralization ( ); GO:0004505 phenylalanine 4-monooxygenase activity ( ); GO:0042481 regulation of odontogenesis ( ); GO:0004062 aryl sulfotransferase activity ( ); GO:0005218 intracellular ligand-gated calcium channel activity ( ); GO:0005219 ryanodine-sensitive calcium-release channel activity ( ); GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen ( ); GO:0046146 tetrahydrobiopterin metabolic process ( ); GO:0006558 L-phenylalanine metabolic process ( ); GO:0006559 L-phenylalanine catabolic process ( ); GO:0042136 neurotransmitter biosynthetic process ( ); GO:0015278 calcium-release channel activity ( ); GO:0042403 thyroid hormone metabolic process ( ); GO:0042423 catecholamine biosynthetic process ( ); GO:0006570 tyrosine metabolic process ( ); GO:0044447 axoneme part ( ); GO:0005217 intracellular ligand-gated ion channel activity ( ); GO:0009074 aromatic amino acid family catabolic process ( ); GO:0019438 aromatic compound biosynthetic process ( ); GO:0009434 microtubule-based flagellum ( ); GO:0042558 pteridine and derivative metabolic process ( ); GO:0042133 neurotransmitter metabolic process ( ); GO:0005930 axoneme ( ); GO:0006519 cellular amino acid and derivative metabolic process ( ); GO:0016597 amino acid binding ( ); GO:0006066 cellular alcohol metabolic process ( ); ----------------GO-------------- GO:0018958 phenol metabolic process ( 7.92974451699315e-05 ); GO:0006576 biogenic amine metabolic process ( 0.000450954530599726 ); GO:0006571 tyrosine biosynthetic process ( 0.000502689388227062 ); GO:0009073 aromatic amino acid family biosynthetic process ( 0.000502689388227062 ); GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway ( 0.000502689388227062 ); GO:0018126 protein amino acid hydroxylation ( 0.000502689388227062 ); GO:0046417 chorismate metabolic process ( 0.000502689388227062 ); GO:0070173 regulation of enamel mineralization ( 0.000502689388227062 ); GO:0006575 amino acid derivative metabolic process ( 0.00085078190296546 ); GO:0070166 enamel mineralization ( 0.001005151338062 ); GO:0070170 regulation of tooth mineralization ( 0.001005151338062 ); GO:0001520 outer dense fiber ( 0.001005151338062 ); GO:0030314 junctional membrane complex ( 0.001005151338062 ); GO:0006725 cellular aromatic compound metabolic process ( 0.00118528503262949 ); GO:0034505 tooth mineralization ( 0.00150738594097877 ); GO:0004505 phenylalanine 4-monooxygenase activity ( 0.00150738594097877 ); GO:0042481 regulation of odontogenesis ( 0.0020093932884192 ); GO:0004062 aryl sulfotransferase activity ( 0.0020093932884192 ); GO:0005218 intracellular ligand-gated calcium channel activity ( 0.00251117347179275 ); GO:0005219 ryanodine-sensitive calcium-release channel activity ( 0.00251117347179275 ); GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen ( 0.00301272658247664 ); GO:0046146 tetrahydrobiopterin metabolic process ( 0.00351405271181648 ); GO:0006558 L-phenylalanine metabolic process ( 0.00401515195112467 ); GO:0006559 L-phenylalanine catabolic process ( 0.00401515195112467 ); GO:0042136 neurotransmitter biosynthetic process ( 0.00401515195112467 ); GO:0015278 calcium-release channel activity ( 0.00401515195112467 ); GO:0042403 thyroid hormone metabolic process ( 0.00451602439168231 ); GO:0042423 catecholamine biosynthetic process ( 0.00451602439168231 ); GO:0006570 tyrosine metabolic process ( 0.00551708924150862 ); GO:0044447 axoneme part ( 0.00551708924150862 ); GO:0005217 intracellular ligand-gated ion channel activity ( 0.00601728183317907 ); GO:0009074 aromatic amino acid family catabolic process ( 0.00651724799090048 ); GO:0019438 aromatic compound biosynthetic process ( 0.00651724799090048 ); GO:0009434 microtubule-based flagellum ( 0.00651724799090048 ); GO:0042558 pteridine and derivative metabolic process ( 0.00751650136894844 ); GO:0042133 neurotransmitter metabolic process ( 0.00801578877141895 ); GO:0005930 axoneme ( 0.00801578877141895 ); GO:0006519 cellular amino acid and derivative metabolic process ( 0.00830210802226479 ); GO:0016597 amino acid binding ( 0.00951229492480987 ); GO:0006066 cellular alcohol metabolic process ( 0.00953782417892728 ); ----------------KEGG-------------- ( 0.00451602439168231 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3653 ========================= ----------------C2-------------- BIOCARTA_AKAP13_PATHWAY ( 0.00601728183317907 ); BIOCARTA_AKAPCENTROSOME_PATHWAY ( 0.00701698780579418 ); REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 ( 0.00701698780579418 ); BIOCARTA_CDC42RAC_PATHWAY ( 0.00801578877141895 ); BIOCARTA_UCALPAIN_PATHWAY ( 0.00851485010423025 ); REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE ( 0.00851485010423025 ); REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT ( 0.00851485010423025 ); REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK ( 0.00851485010423025 ); BIOCARTA_CARDIACEGF_PATHWAY ( 0.00901368545837389 ); BIOCARTA_MAL_PATHWAY ( 0.00951229492480987 ); ----------------C3-------------- V$MYB_Q6 ( 0.00341761181540652 ); V$PAX2_02 ( 0.00408492973498161 ); V$MMEF2_Q6 ( 0.00485250329261952 ); ----------------C4-------------- ( ); ----------------C5-------------- ION_BINDING ( 0.00730599503707846 ); DRUG_BINDING ( 0.00751650136894844 ); ADENYLATE_CYCLASE_ACTIVATION ( 0.00901368545837389 ); ----------------GOSLIM-------------- GO:0004940 beta1-adrenergic receptor activity ( ); GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine ( ); GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine ( ); GO:0002024 diet induced thermogenesis ( ); GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure ( ); GO:0003099 positive regulation of the force of heart contraction by chemical signal ( ); GO:0004939 beta-adrenergic receptor activity ( ); GO:0003057 regulation of the force of heart contraction by chemical signal ( ); GO:0031649 heat generation ( ); GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine ( ); GO:0040015 negative regulation of multicellular organism growth ( ); GO:0050873 brown fat cell differentiation ( ); GO:0010460 positive regulation of heart rate ( ); GO:0042346 positive regulation of NF-kappaB import into nucleus ( ); GO:0044253 positive regulation of multicellular organismal metabolic process ( ); GO:0003084 positive regulation of systemic arterial blood pressure ( ); GO:0003085 negative regulation of systemic arterial blood pressure ( ); GO:0005527 macrolide binding ( ); GO:0005528 FK506 binding ( ); GO:0002021 response to dietary excess ( ); GO:0043149 stress fiber formation ( ); GO:0044246 regulation of multicellular organismal metabolic process ( ); GO:0045823 positive regulation of heart contraction ( ); GO:0004935 adrenoceptor activity ( ); GO:0042993 positive regulation of transcription factor import into nucleus ( ); GO:0045776 negative regulation of blood pressure ( ); GO:0001659 temperature homeostasis ( ); GO:0002026 regulation of the force of heart contraction ( ); GO:0045777 positive regulation of blood pressure ( ); GO:0009409 response to cold ( ); GO:0042345 regulation of NF-kappaB import into nucleus ( ); GO:0042348 NF-kappaB import into nucleus ( ); GO:0042596 fear response ( ); GO:0042307 positive regulation of protein import into nucleus ( ); GO:0002027 regulation of heart rate ( ); GO:0046824 positive regulation of nucleocytoplasmic transport ( ); ----------------GO-------------- GO:0004940 beta1-adrenergic receptor activity ( 0.000502689388227062 ); GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine ( 0.001005151338062 ); GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine ( 0.00150738594097877 ); GO:0002024 diet induced thermogenesis ( 0.00150738594097877 ); GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure ( 0.00150738594097877 ); GO:0003099 positive regulation of the force of heart contraction by chemical signal ( 0.00150738594097877 ); GO:0004939 beta-adrenergic receptor activity ( 0.00150738594097877 ); GO:0003057 regulation of the force of heart contraction by chemical signal ( 0.0020093932884192 ); GO:0031649 heat generation ( 0.00251117347179275 ); GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine ( 0.00301272658247664 ); GO:0040015 negative regulation of multicellular organism growth ( 0.00301272658247664 ); GO:0050873 brown fat cell differentiation ( 0.00301272658247664 ); GO:0010460 positive regulation of heart rate ( 0.00351405271181648 ); GO:0042346 positive regulation of NF-kappaB import into nucleus ( 0.00351405271181648 ); GO:0044253 positive regulation of multicellular organismal metabolic process ( 0.00351405271181648 ); GO:0003084 positive regulation of systemic arterial blood pressure ( 0.00401515195112467 ); GO:0003085 negative regulation of systemic arterial blood pressure ( 0.00401515195112467 ); GO:0005527 macrolide binding ( 0.00401515195112467 ); GO:0005528 FK506 binding ( 0.00401515195112467 ); GO:0002021 response to dietary excess ( 0.00451602439168231 ); GO:0043149 stress fiber formation ( 0.00451602439168231 ); GO:0044246 regulation of multicellular organismal metabolic process ( 0.00451602439168231 ); GO:0045823 positive regulation of heart contraction ( 0.00451602439168231 ); GO:0004935 adrenoceptor activity ( 0.00451602439168231 ); GO:0042993 positive regulation of transcription factor import into nucleus ( 0.00551708924150862 ); GO:0045776 negative regulation of blood pressure ( 0.00551708924150862 ); GO:0001659 temperature homeostasis ( 0.00601728183317907 ); GO:0002026 regulation of the force of heart contraction ( 0.00601728183317907 ); GO:0045777 positive regulation of blood pressure ( 0.00601728183317907 ); GO:0009409 response to cold ( 0.00651724799090048 ); GO:0042345 regulation of NF-kappaB import into nucleus ( 0.00651724799090048 ); GO:0042348 NF-kappaB import into nucleus ( 0.00651724799090048 ); GO:0042596 fear response ( 0.00651724799090048 ); GO:0042307 positive regulation of protein import into nucleus ( 0.00701698780579418 ); GO:0002027 regulation of heart rate ( 0.00751650136894844 ); GO:0046824 positive regulation of nucleocytoplasmic transport ( 0.00901368545837389 ); ----------------KEGG-------------- hsa04150 mTOR signaling pathway ( 0.0233820178667958 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0253490717712604 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0253490717712604 ); hsa04920 Adipocytokine signaling pathway ( 0.0326938070017745 ); hsa04520 Adherens junction ( 0.0370767003918034 ); hsa04512 ECM-receptor interaction ( 0.0409575922099408 ); hsa04350 TGF-beta signaling pathway ( 0.0424092934761842 ); hsa04660 T cell receptor signaling pathway ( 0.0462708331666259 ); hsa04540 Gap junction ( 0.047234025639284 ); ----------------CARTA-------------- ( 0.00150738594097877 ); ----------------RBP-------------- ( ); ----------------immu-------------- Cytokine_receptors ( 0.00953782417892728 ); TCR_signalling_pathway ( 0.0477152934952019 ); ----------------ARE-------------- ( ); ============================ group3883 ========================= ----------------C2-------------- KEGG_NON_HOMOLOGOUS_END_JOINING ( 0.00651724799090048 ); REACTOME_POLYMERASE_SWITCHING ( 0.00701698780579418 ); REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE ( 0.00701698780579418 ); BIOCARTA_EIF_PATHWAY ( 0.00801578877141895 ); ----------------C3-------------- CTACTGT,MIR-199A ( 0.00228510164977391 ); V$TITF1_Q3 ( 0.00334282204120725 ); CTTTGCA,MIR-527 ( 0.00425011158058009 ); GTCAACC,MIR-380-5P ( 0.00951229492480987 ); ----------------C4-------------- module_244 ( 8.62194410314746e-05 ); module_197 ( 0.00312318268001195 ); module_252 ( 0.00544535409475451 ); module_429 ( 0.00701698780579418 ); module_198 ( 0.00888074183166094 ); module_372 ( 0.00951229492480987 ); ----------------C5-------------- HELICASE_ACTIVITY ( 0.000264117307950331 ); NUCLEOPLASM ( 0.000270521388954225 ); NUCLEAR_LUMEN ( 0.000684105770999329 ); ORGANELLE_LUMEN ( 0.00112617057260401 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00112617057260401 ); CHROMOSOME ( 0.00165197487629972 ); NUCLEAR_PART ( 0.00211419211514024 ); REGULATION_OF_GENE_EXPRESSION ( 0.00364807202049226 ); EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX ( 0.00501667012473783 ); NUCLEAR_REPLICATION_FORK ( 0.00501667012473783 ); NUCLEOSOME_ASSEMBLY ( 0.00501667012473783 ); S_PHASE_OF_MITOTIC_CELL_CYCLE ( 0.00501667012473783 ); NUCLEOTIDE_BINDING ( 0.0050315019893465 ); REGULATION_OF_CELLULAR_METABOLIC_PROCESS ( 0.005550380592936 ); REGULATION_OF_METABOLIC_PROCESS ( 0.00577650718964392 ); NUCLEAR_MATRIX ( 0.00601728183317907 ); PROTEIN_COMPLEX ( 0.00618024690092444 ); BIOPOLYMER_METABOLIC_PROCESS ( 0.00620971566466355 ); S_PHASE ( 0.00701698780579418 ); DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY ( 0.00701698780579418 ); DNA_REPLICATION_INITIATION ( 0.00751650136894844 ); CHROMATIN_ASSEMBLY ( 0.00801578877141895 ); RNA_POLYMERASE_ACTIVITY ( 0.00801578877141895 ); MACROMOLECULAR_COMPLEX_ASSEMBLY ( 0.0080195255907171 ); CHROMATIN_REMODELING_COMPLEX ( 0.00851485010423025 ); REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER ( 0.00853141217485797 ); MACROMOLECULAR_COMPLEX ( 0.00899093881720132 ); REPLICATION_FORK ( 0.00901368545837389 ); DNA_POLYMERASE_ACTIVITY ( 0.00901368545837389 ); CELLULAR_COMPONENT_ASSEMBLY ( 0.00905781552738061 ); ----------------GOSLIM-------------- GO:0000726 non-recombinational repair ( 4.70086781184865e-06 ); GO:0006303 double-strand break repair via nonhomologous end joining ( 0.000189018384796734 ); GO:0016585 chromatin remodeling complex ( 0.000892506073763808 ); GO:0003676 nucleic acid binding ( 0.00119184928250112 ); GO:0006302 double-strand break repair ( 0.00205068009179608 ); GO:0005654 nucleoplasm ( 0.00459550986679341 ); GO:0006272 leading strand elongation ( 0.00463304810882146 ); GO:0006273 lagging strand elongation ( 0.00832516233597287 ); GO:0043234 protein complex ( 4.70086781184865e-06 ); GO:0031213 RSF complex ( 0.000189018384796734 ); GO:0004677 DNA-dependent protein kinase activity ( 0.000892506073763808 ); GO:0031491 nucleosome binding ( 0.00119184928250112 ); GO:0003682 chromatin binding ( 0.00205068009179608 ); GO:0006271 DNA strand elongation during DNA replication ( 0.00459550986679341 ); GO:0031981 nuclear lumen ( 0.00463304810882146 ); GO:0004386 helicase activity ( 0.00832516233597287 ); GO:0016584 nucleosome positioning ( 4.70086781184865e-06 ); GO:0043044 ATP-dependent chromatin remodeling ( 0.000189018384796734 ); GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex ( 0.000892506073763808 ); GO:0070419 nonhomologous end joining complex ( 0.00119184928250112 ); GO:0003896 DNA primase activity ( 0.00205068009179608 ); GO:0003677 DNA binding ( 0.00459550986679341 ); GO:0032991 macromolecular complex ( 0.00463304810882146 ); GO:0022616 DNA strand elongation ( 0.00832516233597287 ); GO:0005634 nucleus ( 4.70086781184865e-06 ); GO:0005658 alpha DNA polymerase:primase complex ( 0.000189018384796734 ); GO:0070013 intracellular organelle lumen ( 0.000892506073763808 ); GO:0043233 organelle lumen ( 0.00119184928250112 ); GO:0016568 chromatin modification ( 0.00205068009179608 ); GO:0031974 membrane-enclosed lumen ( 0.00459550986679341 ); GO:0044428 nuclear part ( 0.00463304810882146 ); GO:0000731 DNA synthesis during DNA repair ( 0.00832516233597287 ); GO:0001882 nucleoside binding ( 4.70086781184865e-06 ); GO:0005852 eukaryotic translation initiation factor 3 complex ( 0.000189018384796734 ); GO:0016514 SWI/SNF complex ( 0.000892506073763808 ); GO:0030894 replisome ( 0.00119184928250112 ); GO:0043601 nuclear replisome ( 0.00205068009179608 ); GO:0000084 S phase of mitotic cell cycle ( 0.00459550986679341 ); GO:0006281 DNA repair ( 0.00463304810882146 ); GO:0043596 nuclear replication fork ( 0.00832516233597287 ); GO:0006325 establishment or maintenance of chromatin architecture ( 4.70086781184865e-06 ); GO:0051320 S phase ( 0.000189018384796734 ); GO:0042393 histone binding ( 0.000892506073763808 ); GO:0034984 cellular response to DNA damage stimulus ( 0.00119184928250112 ); GO:0016563 transcription activator activity ( 0.00205068009179608 ); GO:0003712 transcription cofactor activity ( 0.00459550986679341 ); GO:0034961 cellular biopolymer biosynthetic process ( 0.00463304810882146 ); GO:0043284 biopolymer biosynthetic process ( 0.00832516233597287 ); ----------------GO-------------- GO:0000726 non-recombinational repair ( 8.1724266632802e-06 ); GO:0006303 double-strand break repair via nonhomologous end joining ( 8.1724266632802e-06 ); GO:0016585 chromatin remodeling complex ( 7.92974451699315e-05 ); GO:0003676 nucleic acid binding ( 0.00013215339322236 ); GO:0006302 double-strand break repair ( 0.000158352951622034 ); GO:0005654 nucleoplasm ( 0.000253539460900586 ); GO:0006272 leading strand elongation ( 0.000502689388227062 ); GO:0006273 lagging strand elongation ( 0.000502689388227062 ); GO:0043234 protein complex ( 0.00083119680547956 ); GO:0031213 RSF complex ( 0.001005151338062 ); GO:0004677 DNA-dependent protein kinase activity ( 0.001005151338062 ); GO:0031491 nucleosome binding ( 0.001005151338062 ); GO:0003682 chromatin binding ( 0.00118528503262949 ); GO:0006271 DNA strand elongation during DNA replication ( 0.00150738594097877 ); GO:0031981 nuclear lumen ( 0.00162261381003981 ); GO:0004386 helicase activity ( 0.00198508374505401 ); GO:0016584 nucleosome positioning ( 0.0020093932884192 ); GO:0043044 ATP-dependent chromatin remodeling ( 0.0020093932884192 ); GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex ( 0.0020093932884192 ); GO:0070419 nonhomologous end joining complex ( 0.0020093932884192 ); GO:0003896 DNA primase activity ( 0.0020093932884192 ); GO:0003677 DNA binding ( 0.0022691062968712 ); GO:0032991 macromolecular complex ( 0.00242636230259896 ); GO:0022616 DNA strand elongation ( 0.00251117347179275 ); GO:0005634 nucleus ( 0.00260370147387531 ); GO:0005658 alpha DNA polymerase:primase complex ( 0.00301272658247664 ); GO:0070013 intracellular organelle lumen ( 0.00356962356344071 ); GO:0043233 organelle lumen ( 0.00387804095975918 ); GO:0016568 chromatin modification ( 0.00392284723071534 ); GO:0031974 membrane-enclosed lumen ( 0.00419407859523005 ); GO:0044428 nuclear part ( 0.00425725139871938 ); GO:0000731 DNA synthesis during DNA repair ( 0.00451602439168231 ); GO:0001882 nucleoside binding ( 0.00451602439168231 ); GO:0005852 eukaryotic translation initiation factor 3 complex ( 0.00501667012473783 ); GO:0016514 SWI/SNF complex ( 0.00601728183317907 ); GO:0030894 replisome ( 0.00601728183317907 ); GO:0043601 nuclear replisome ( 0.00601728183317907 ); GO:0000084 S phase of mitotic cell cycle ( 0.00651724799090048 ); GO:0006281 DNA repair ( 0.00667474797932872 ); GO:0043596 nuclear replication fork ( 0.00701698780579418 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00796355038137038 ); GO:0051320 S phase ( 0.00851485010423025 ); GO:0042393 histone binding ( 0.00851485010423025 ); GO:0034984 cellular response to DNA damage stimulus ( 0.00853141217485797 ); GO:0016563 transcription activator activity ( 0.009176753961415 ); GO:0003712 transcription cofactor activity ( 0.00947720349864284 ); GO:0034961 cellular biopolymer biosynthetic process ( 0.00961649347398384 ); GO:0043284 biopolymer biosynthetic process ( 0.00961649347398384 ); ----------------KEGG-------------- hsa03450 Non-homologous end-joining ( 0.00651724799090048 ); hsa03030 DNA replication ( 0.0179541830201035 ); hsa00240 Pyrimidine metabolism ( 0.0448244012277662 ); ----------------CARTA-------------- ionpathway ( 0.00401515195112467 ); mcalpainpathway ( 0.00651724799090048 ); hivnefpathway ( 0.0149821164494092 ); ----------------RBP-------------- TDP-43_iCLIP_(Tollervey_2011) ( 0.00169756992233302 ); ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.0113844338656412 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0116068157678167 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0141631088708994 ); TIAL1_iCLIP_(Wang_2010) ( 0.0147415161730222 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2 ========================= ----------------C2-------------- ( ); ----------------C3-------------- GTTATAT,MIR-410 ( 0.00065204622530591 ); ATACCTC,MIR-202 ( 0.00196386045326284 ); AAAYWAACM_V$HFH4_01 ( 0.00335551646983232 ); ----------------C4-------------- ( ); ----------------C5-------------- GTPASE_ACTIVATOR_ACTIVITY ( 0.000276675389676741 ); GTPASE_REGULATOR_ACTIVITY ( 0.00120183076327647 ); ENZYME_ACTIVATOR_ACTIVITY ( 0.00128457091305522 ); RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY ( 0.00811578182091532 ); ENZYME_REGULATOR_ACTIVITY ( 0.00825832068119497 ); ----------------GOSLIM-------------- GO:0019992 diacylglycerol binding ( ); GO:0000407 pre-autophagosomal structure ( ); GO:0034045 pre-autophagosomal structure membrane ( ); GO:0017034 Rap guanyl-nucleotide exchange factor activity ( ); GO:0046582 Rap GTPase activator activity ( ); GO:0000045 autophagic vacuole formation ( ); GO:0005096 GTPase activator activity ( ); GO:0005776 autophagic vacuole ( ); GO:0016236 macroautophagy ( ); GO:0042169 SH2 domain binding ( ); GO:0008047 enzyme activator activity ( ); GO:0009267 cellular response to starvation ( ); ----------------GO-------------- GO:0019992 diacylglycerol binding ( 0.000384465688052981 ); GO:0000407 pre-autophagosomal structure ( 0.000904658948094661 ); GO:0034045 pre-autophagosomal structure membrane ( 0.000904658948094661 ); GO:0017034 Rap guanyl-nucleotide exchange factor activity ( 0.000904658948094661 ); GO:0046582 Rap GTPase activator activity ( 0.00135671556010364 ); GO:0000045 autophagic vacuole formation ( 0.0036142725596775 ); GO:0005096 GTPase activator activity ( 0.00380255753436388 ); GO:0005776 autophagic vacuole ( 0.00451602439168164 ); GO:0016236 macroautophagy ( 0.0049666282130606 ); GO:0042169 SH2 domain binding ( 0.00721692892746606 ); GO:0008047 enzyme activator activity ( 0.00795546364144499 ); GO:0009267 cellular response to starvation ( 0.00991131773973564 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0379086668887737 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group20 ========================= ----------------C2-------------- REACTOME_PECAM1_INTERACTIONS ( 0.00541705072317444 ); BIOCARTA_IL3_PATHWAY ( 0.00676723102421728 ); BIOCARTA_EPO_PATHWAY ( 0.00856493693858129 ); BIOCARTA_NKCELLS_PATHWAY ( 0.00901391125515316 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY ( 0.00193813089733599 ); HYDROLASE_ACTIVITY__ACTING_ON_ESTER_BONDS ( 0.00580921463129915 ); G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY ( 0.00872236674910736 ); ----------------GOSLIM-------------- GO:0002031 G-protein coupled receptor internalization ( ); GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway ( ); GO:0022401 adaptation of signaling pathway ( ); GO:0070290 NAPE-specific phospholipase D activity ( ); GO:0031623 receptor internalization ( ); GO:0004630 phospholipase D activity ( ); GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway ( ); GO:0031526 brush border membrane ( ); GO:0042578 phosphoric ester hydrolase activity ( ); GO:0007186 G-protein coupled receptor protein signaling pathway ( ); GO:0031253 cell projection membrane ( ); ----------------GO-------------- GO:0002031 G-protein coupled receptor internalization ( 0.000904658948094661 ); GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway ( 0.00226028338010587 ); GO:0022401 adaptation of signaling pathway ( 0.00226028338010587 ); GO:0070290 NAPE-specific phospholipase D activity ( 0.00226028338010587 ); GO:0031623 receptor internalization ( 0.0031631244212782 ); GO:0004630 phospholipase D activity ( 0.0031631244212782 ); GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway ( 0.0036142725596775 ); GO:0031526 brush border membrane ( 0.00451602439168164 ); GO:0042578 phosphoric ester hydrolase activity ( 0.0081062394640593 ); GO:0007186 G-protein coupled receptor protein signaling pathway ( 0.00811985672545299 ); GO:0031253 cell projection membrane ( 0.00856493693858129 ); ----------------KEGG-------------- hsa00565 Ether lipid metabolism ( 0.0143875237307112 ); hsa00564 Glycerophospholipid metabolism ( 0.0290316555950966 ); hsa04662 B cell receptor signaling pathway ( 0.0290316555950966 ); hsa04520 Adherens junction ( 0.0334309208233938 ); hsa04660 T cell receptor signaling pathway ( 0.0417407401053659 ); hsa04912 GnRH signaling pathway ( 0.0439169525254034 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- BCR_signalling_pathway ( 0.0329917930236668 ); TCR_signalling_pathway ( 0.0430469952927979 ); ----------------ARE-------------- ( ); ============================ group23 ========================= ----------------C2-------------- ( ); ----------------C3-------------- RNGTGGGC_UNKNOWN ( 0.0016001241599052 ); V$IRF1_Q6 ( 0.00338895991422319 ); V$NFAT_Q4_01 ( 0.0035585420496368 ); ----------------C4-------------- ( 0.00268986764726141 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0009996 negative regulation of cell fate specification ( ); GO:0042659 regulation of cell fate specification ( ); GO:0042660 positive regulation of cell fate specification ( ); GO:0009021 tRNA (uracil-5-)-methyltransferase activity ( ); GO:0016300 tRNA (uracil) methyltransferase activity ( ); GO:0019975 interleukin-17 binding ( ); GO:0030368 interleukin-17 receptor activity ( ); GO:0010453 regulation of cell fate commitment ( ); GO:0010454 negative regulation of cell fate commitment ( ); GO:0000083 regulation of transcription of G1/S-phase of mitotic cell cycle ( ); GO:0042989 sequestering of actin monomers ( ); GO:0007638 mechanosensory behavior ( ); GO:0042491 auditory receptor cell differentiation ( ); GO:0008175 tRNA methyltransferase activity ( ); GO:0060113 inner ear receptor cell differentiation ( ); GO:0005452 inorganic anion exchanger activity ( ); GO:0042490 mechanoreceptor differentiation ( ); GO:0015380 anion exchanger activity ( ); GO:0008173 RNA methyltransferase activity ( ); GO:0015106 bicarbonate transmembrane transporter activity ( ); GO:0015108 chloride transmembrane transporter activity ( ); GO:0015301 anion:anion antiporter activity ( ); ----------------GO-------------- GO:0009996 negative regulation of cell fate specification ( 0.000452420449404412 ); GO:0042659 regulation of cell fate specification ( 0.000452420449404412 ); GO:0042660 positive regulation of cell fate specification ( 0.000452420449404412 ); GO:0009021 tRNA (uracil-5-)-methyltransferase activity ( 0.000452420449404412 ); GO:0016300 tRNA (uracil) methyltransferase activity ( 0.000452420449404412 ); GO:0019975 interleukin-17 binding ( 0.000452420449404412 ); GO:0030368 interleukin-17 receptor activity ( 0.000452420449404412 ); GO:0010453 regulation of cell fate commitment ( 0.000904658948094661 ); GO:0010454 negative regulation of cell fate commitment ( 0.000904658948094661 ); GO:0000083 regulation of transcription of G1/S-phase of mitotic cell cycle ( 0.00135671556010364 ); GO:0042989 sequestering of actin monomers ( 0.00271179471606597 ); GO:0007638 mechanosensory behavior ( 0.0036142725596775 ); GO:0042491 auditory receptor cell differentiation ( 0.00406523919517987 ); GO:0008175 tRNA methyltransferase activity ( 0.00406523919517987 ); GO:0060113 inner ear receptor cell differentiation ( 0.0049666282130606 ); GO:0005452 inorganic anion exchanger activity ( 0.00586729198586233 ); GO:0042490 mechanoreceptor differentiation ( 0.0063173520649431 ); GO:0015380 anion exchanger activity ( 0.00766644583845122 ); GO:0008173 RNA methyltransferase activity ( 0.00811578182091532 ); GO:0015106 bicarbonate transmembrane transporter activity ( 0.00811578182091532 ); GO:0015108 chloride transmembrane transporter activity ( 0.00811578182091532 ); GO:0015301 anion:anion antiporter activity ( 0.00856493693858129 ); ----------------KEGG-------------- ( 0.0148341534213827 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group30 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN ( 0.00451602439168164 ); REGULATION_OF_JAK_STAT_CASCADE ( 0.00541705072317444 ); ACTIN_FILAMENT_BUNDLE_FORMATION ( 0.00541705072317444 ); TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN ( 0.00586729198586233 ); POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION ( 0.00586729198586233 ); PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 0.0059833570552357 ); PHOSPHORYLATION ( 0.00736547438772435 ); REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION ( 0.00811578182091532 ); ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CELL_POLARITY ( 0.00856493693858129 ); POSITIVE_REGULATION_OF_PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 0.00901391125515316 ); ----------------GOSLIM-------------- GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0042503 tyrosine phosphorylation of Stat3 protein ( ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( ); GO:0046427 positive regulation of JAK-STAT cascade ( ); GO:0004190 aspartic-type endopeptidase activity ( ); GO:0070001 aspartic-type peptidase activity ( ); GO:0032268 regulation of cellular protein metabolic process ( ); GO:0051017 actin filament bundle formation ( ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( ); ----------------GO-------------- GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ( 0.00451602439168164 ); GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein ( 0.0063173520649431 ); GO:0042503 tyrosine phosphorylation of Stat3 protein ( 0.00676723102421728 ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( 0.00811578182091532 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00901391125515316 ); GO:0004190 aspartic-type endopeptidase activity ( 0.00901391125515316 ); GO:0070001 aspartic-type peptidase activity ( 0.00901391125515316 ); GO:0032268 regulation of cellular protein metabolic process ( 0.00919805372262227 ); GO:0051017 actin filament bundle formation ( 0.0094627048343161 ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( 0.00991131773973564 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2721 ========================= ----------------C2-------------- BIOCARTA_ACE2_PATHWAY ( 0.00586729198586233 ); KEGG_RENIN_ANGIOTENSIN_SYSTEM ( 0.00766644583845122 ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.0094627048343161 ); ----------------C5-------------- CARBOXYPEPTIDASE_ACTIVITY ( 0.00541705072317444 ); INTERACTION_WITH_HOST ( 0.00766644583845122 ); ----------------GOSLIM-------------- GO:0003051 angiotensin-mediated drinking behavior ( ); GO:0002005 angiotensin catabolic process in blood ( ); GO:0042756 drinking behavior ( ); GO:0044254 multicellular organismal protein catabolic process ( ); GO:0044256 protein digestion ( ); GO:0044266 multicellular organismal macromolecule catabolic process ( ); GO:0044268 multicellular organismal protein metabolic process ( ); GO:0001618 viral receptor activity ( ); GO:0016426 tRNA (adenine)-methyltransferase activity ( ); GO:0016429 tRNA (adenine-N1-)-methyltransferase activity ( ); GO:0002035 brain renin-angiotensin system ( ); GO:0030488 tRNA methylation ( ); GO:0046813 virion attachment, binding of host cell surface receptor ( ); GO:0008241 peptidyl-dipeptidase activity ( ); GO:0002016 regulation of blood volume by renin-angiotensin ( ); GO:0002002 regulation of angiotensin levels in blood ( ); GO:0060177 regulation of angiotensin metabolic process ( ); GO:0019062 virion attachment to host cell surface receptor ( ); GO:0001510 RNA methylation ( ); GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin ( ); GO:0032800 receptor biosynthetic process ( ); GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ( ); GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin ( ); GO:0008175 tRNA methyltransferase activity ( ); GO:0030260 entry into host cell ( ); GO:0044409 entry into host ( ); GO:0046718 entry of virus into host cell ( ); GO:0051806 entry into cell of other organism during symbiotic interaction ( ); GO:0051828 entry into other organism during symbiotic interaction ( ); GO:0052126 movement in host environment ( ); GO:0052192 movement in environment of other organism during symbiotic interaction ( ); GO:0006400 tRNA modification ( ); GO:0042312 regulation of vasodilation ( ); GO:0001948 glycoprotein binding ( ); GO:0001990 regulation of systemic arterial blood pressure by hormone ( ); GO:0019229 regulation of vasoconstriction ( ); GO:0050886 endocrine process ( ); GO:0005634 nucleus ( ); GO:0008173 RNA methyltransferase activity ( ); GO:0051701 interaction with host ( ); ----------------GO-------------- GO:0003051 angiotensin-mediated drinking behavior ( 0.000452420449404412 ); GO:0002005 angiotensin catabolic process in blood ( 0.000904658948094661 ); GO:0042756 drinking behavior ( 0.000904658948094661 ); GO:0044254 multicellular organismal protein catabolic process ( 0.000904658948094661 ); GO:0044256 protein digestion ( 0.000904658948094661 ); GO:0044266 multicellular organismal macromolecule catabolic process ( 0.000904658948094661 ); GO:0044268 multicellular organismal protein metabolic process ( 0.000904658948094661 ); GO:0001618 viral receptor activity ( 0.000904658948094661 ); GO:0016426 tRNA (adenine)-methyltransferase activity ( 0.000904658948094661 ); GO:0016429 tRNA (adenine-N1-)-methyltransferase activity ( 0.000904658948094661 ); GO:0002035 brain renin-angiotensin system ( 0.00135671556010364 ); GO:0030488 tRNA methylation ( 0.00135671556010364 ); GO:0046813 virion attachment, binding of host cell surface receptor ( 0.00135671556010364 ); GO:0008241 peptidyl-dipeptidase activity ( 0.00135671556010364 ); GO:0002016 regulation of blood volume by renin-angiotensin ( 0.0018085903494427 ); GO:0002002 regulation of angiotensin levels in blood ( 0.00226028338010587 ); GO:0060177 regulation of angiotensin metabolic process ( 0.00226028338010587 ); GO:0019062 virion attachment to host cell surface receptor ( 0.00271179471606597 ); GO:0001510 RNA methylation ( 0.0036142725596775 ); GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin ( 0.0036142725596775 ); GO:0032800 receptor biosynthetic process ( 0.0036142725596775 ); GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ( 0.00406523919517987 ); GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin ( 0.00406523919517987 ); GO:0008175 tRNA methyltransferase activity ( 0.00406523919517987 ); GO:0030260 entry into host cell ( 0.00541705072317444 ); GO:0044409 entry into host ( 0.00541705072317444 ); GO:0046718 entry of virus into host cell ( 0.00541705072317444 ); GO:0051806 entry into cell of other organism during symbiotic interaction ( 0.00541705072317444 ); GO:0051828 entry into other organism during symbiotic interaction ( 0.00541705072317444 ); GO:0052126 movement in host environment ( 0.00541705072317444 ); GO:0052192 movement in environment of other organism during symbiotic interaction ( 0.00541705072317444 ); GO:0006400 tRNA modification ( 0.00586729198586233 ); GO:0042312 regulation of vasodilation ( 0.00586729198586233 ); GO:0001948 glycoprotein binding ( 0.00721692892746606 ); GO:0001990 regulation of systemic arterial blood pressure by hormone ( 0.00766644583845122 ); GO:0019229 regulation of vasoconstriction ( 0.00766644583845122 ); GO:0050886 endocrine process ( 0.00766644583845122 ); GO:0005634 nucleus ( 0.00778271713386617 ); GO:0008173 RNA methyltransferase activity ( 0.00811578182091532 ); GO:0051701 interaction with host ( 0.00991131773973564 ); ----------------KEGG-------------- ( 0.00766644583845122 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2901 ========================= ----------------C2-------------- BIOCARTA_VITCB_PATHWAY ( 0.0049666282130606 ); BIOCARTA_ACE2_PATHWAY ( 0.00586729198586233 ); BIOCARTA_PLATELETAPP_PATHWAY ( 0.0063173520649431 ); BIOCARTA_AMI_PATHWAY ( 0.00856493693858129 ); ----------------C3-------------- ( 0.00538441300474091 ); ----------------C4-------------- ( ); ----------------C5-------------- EPITHELIAL_TO_MESENCHYMAL_TRANSITION ( 0.00406523919517987 ); REGULATION_OF_GENE_SPECIFIC_TRANSCRIPTION ( 0.00451602439168164 ); SPECIFIC_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY ( 0.0049666282130606 ); NEGATIVE_REGULATION_OF_ANGIOGENESIS ( 0.00586729198586233 ); ----------------GOSLIM-------------- GO:0048711 positive regulation of astrocyte differentiation ( 0.00229152655167058 ); GO:0030061 mitochondrial crista ( 0.00805583566455518 ); GO:0060317 cardiac epithelial to mesenchymal transition ( 0.00229152655167058 ); GO:0051345 positive regulation of hydrolase activity ( 0.00805583566455518 ); GO:0048710 regulation of astrocyte differentiation ( 0.00229152655167058 ); GO:0000904 cell morphogenesis involved in differentiation ( 0.00805583566455518 ); GO:0014015 positive regulation of gliogenesis ( 0.00229152655167058 ); GO:0045687 positive regulation of glial cell differentiation ( 0.00805583566455518 ); GO:0005587 collagen type IV ( 0.00229152655167058 ); GO:0030935 sheet-forming collagen ( 0.00805583566455518 ); GO:0032582 negative regulation of gene-specific transcription ( 0.00229152655167058 ); GO:0005102 receptor binding ( 0.00805583566455518 ); GO:0044421 extracellular region part ( 0.00229152655167058 ); GO:0048708 astrocyte differentiation ( 0.00805583566455518 ); GO:0008191 metalloendopeptidase inhibitor activity ( 0.00229152655167058 ); GO:0014013 regulation of gliogenesis ( 0.00805583566455518 ); GO:0045685 regulation of glial cell differentiation ( 0.00229152655167058 ); GO:0005743 mitochondrial inner membrane ( 0.00805583566455518 ); GO:0001658 ureteric bud branching ( 0.00229152655167058 ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( 0.00805583566455518 ); GO:0035051 cardiac cell differentiation ( 0.00229152655167058 ); GO:0051336 regulation of hydrolase activity ( 0.00805583566455518 ); GO:0008285 negative regulation of cell proliferation ( 0.00229152655167058 ); GO:0019866 organelle inner membrane ( 0.00805583566455518 ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( 0.00229152655167058 ); GO:0030501 positive regulation of bone mineralization ( 0.00805583566455518 ); GO:0005578 proteinaceous extracellular matrix ( 0.00229152655167058 ); GO:0070169 positive regulation of biomineral formation ( 0.00805583566455518 ); GO:0001837 epithelial to mesenchymal transition ( 0.00229152655167058 ); GO:0060389 pathway-restricted SMAD protein phosphorylation ( 0.00805583566455518 ); GO:0031012 extracellular matrix ( 0.00229152655167058 ); GO:0045669 positive regulation of osteoblast differentiation ( 0.00805583566455518 ); GO:0045778 positive regulation of ossification ( 0.00229152655167058 ); GO:0016566 specific transcriptional repressor activity ( 0.00805583566455518 ); GO:0016525 negative regulation of angiogenesis ( 0.00229152655167058 ); GO:0048699 generation of neurons ( 0.00805583566455518 ); GO:0031966 mitochondrial membrane ( 0.00229152655167058 ); GO:0001657 ureteric bud development ( 0.00805583566455518 ); GO:0046852 positive regulation of bone remodeling ( 0.00229152655167058 ); ----------------GO-------------- GO:0048711 positive regulation of astrocyte differentiation ( 0.000904658948094661 ); GO:0030061 mitochondrial crista ( 0.000904658948094661 ); GO:0060317 cardiac epithelial to mesenchymal transition ( 0.00135671556010364 ); GO:0051345 positive regulation of hydrolase activity ( 0.00152585980757399 ); GO:0048710 regulation of astrocyte differentiation ( 0.0018085903494427 ); GO:0000904 cell morphogenesis involved in differentiation ( 0.00260052406090237 ); GO:0014015 positive regulation of gliogenesis ( 0.00271179471606597 ); GO:0045687 positive regulation of glial cell differentiation ( 0.00271179471606597 ); GO:0005587 collagen type IV ( 0.00271179471606597 ); GO:0030935 sheet-forming collagen ( 0.0031631244212782 ); GO:0032582 negative regulation of gene-specific transcription ( 0.0036142725596775 ); GO:0005102 receptor binding ( 0.00375244495457 ); GO:0044421 extracellular region part ( 0.0043322628836783 ); GO:0048708 astrocyte differentiation ( 0.00451602439168164 ); GO:0008191 metalloendopeptidase inhibitor activity ( 0.00451602439168164 ); GO:0014013 regulation of gliogenesis ( 0.0049666282130606 ); GO:0045685 regulation of glial cell differentiation ( 0.0049666282130606 ); GO:0005743 mitochondrial inner membrane ( 0.00534276525094781 ); GO:0001658 ureteric bud branching ( 0.00541705072317444 ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( 0.00541705072317444 ); GO:0035051 cardiac cell differentiation ( 0.00586729198586233 ); GO:0051336 regulation of hydrolase activity ( 0.00589598519776553 ); GO:0008285 negative regulation of cell proliferation ( 0.00620441139014997 ); GO:0019866 organelle inner membrane ( 0.00629388062090985 ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( 0.0063173520649431 ); GO:0030501 positive regulation of bone mineralization ( 0.00676723102421728 ); GO:0005578 proteinaceous extracellular matrix ( 0.00712586988631389 ); GO:0070169 positive regulation of biomineral formation ( 0.00721692892746606 ); GO:0001837 epithelial to mesenchymal transition ( 0.00766644583845122 ); GO:0060389 pathway-restricted SMAD protein phosphorylation ( 0.00766644583845122 ); GO:0031012 extracellular matrix ( 0.00780599621475297 ); GO:0045669 positive regulation of osteoblast differentiation ( 0.00856493693858129 ); GO:0045778 positive regulation of ossification ( 0.00856493693858129 ); GO:0016566 specific transcriptional repressor activity ( 0.00856493693858129 ); GO:0016525 negative regulation of angiogenesis ( 0.0094627048343161 ); GO:0048699 generation of neurons ( 0.0098502722600811 ); GO:0031966 mitochondrial membrane ( 0.0098502722600811 ); GO:0001657 ureteric bud development ( 0.00991131773973564 ); GO:0046852 positive regulation of bone remodeling ( 0.00991131773973564 ); ----------------KEGG-------------- hsa05217 Basal cell carcinoma ( 0.024614601208892 ); hsa04340 Hedgehog signaling pathway ( 0.0254994382357013 ); hsa04350 TGF-beta signaling pathway ( 0.0382496409475928 ); hsa05012 Parkinson's disease ( 0.0499869951083636 ); ----------------CARTA-------------- mitrpathway ( 0.0031631244212782 ); mitochondriapathway ( 0.00721692892746606 ); nfatpathway ( 0.0166188737055817 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2903 ========================= ----------------C2-------------- KEGG_AXON_GUIDANCE ( 0.00145805905005397 ); BIOCARTA_GABA_PATHWAY ( 0.00451602439168164 ); ----------------C3-------------- V$TEF1_Q6 ( 0.0023976878225916 ); V$BACH1_01 ( 0.0035585420496368 ); V$AP1_Q2_01 ( 0.00416443660054718 ); WGGAATGY_V$TEF1_Q6 ( 0.00656586796622094 ); ----------------C4-------------- module_215 ( 0.00676723102421728 ); module_141 ( 0.00721692892746606 ); ----------------C5-------------- GAMETE_GENERATION ( 0.0010827472815447 ); SEXUAL_REPRODUCTION ( 0.00159515151234164 ); SPERMATID_DIFFERENTIATION ( 0.0049666282130606 ); SYSTEM_DEVELOPMENT ( 0.005363133317939 ); REPRODUCTION ( 0.00563748100776774 ); PHOSPHATASE_BINDING ( 0.00586729198586233 ); ION_BINDING ( 0.00589598519776553 ); DEAMINASE_ACTIVITY ( 0.0063173520649431 ); HYDROLASE_ACTIVITY__ACTING_ON_CARBON_NITROGEN__BUT_NOT_PEPTIDE__BONDS__IN_CYCLIC_AMIDINES ( 0.00721692892746606 ); ANATOMICAL_STRUCTURE_DEVELOPMENT ( 0.00844394050550074 ); MULTICELLULAR_ORGANISMAL_DEVELOPMENT ( 0.00921386109108225 ); ----------------GOSLIM-------------- GO:0008892 guanine deaminase activity ( ); GO:0008306 associative learning ( ); GO:0001662 behavioral fear response ( ); GO:0002209 behavioral defense response ( ); GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ( ); GO:0022884 macromolecule transmembrane transporter activity ( ); GO:0042596 fear response ( ); GO:0007214 gamma-aminobutyric acid signaling pathway ( ); GO:0008320 protein transmembrane transporter activity ( ); GO:0005003 ephrin receptor activity ( ); ----------------GO-------------- GO:0008892 guanine deaminase activity ( 0.000452420449404412 ); GO:0008306 associative learning ( 0.00406523919517987 ); GO:0001662 behavioral fear response ( 0.00451602439168164 ); GO:0002209 behavioral defense response ( 0.00451602439168164 ); GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ( 0.0049666282130606 ); GO:0022884 macromolecule transmembrane transporter activity ( 0.0049666282130606 ); GO:0042596 fear response ( 0.00586729198586233 ); GO:0007214 gamma-aminobutyric acid signaling pathway ( 0.00721692892746606 ); GO:0008320 protein transmembrane transporter activity ( 0.00721692892746606 ); GO:0005003 ephrin receptor activity ( 0.00766644583845122 ); ----------------KEGG-------------- hsa04360 Axon guidance ( 0.00145805905005397 ); hsa05014 Amyotrophic lateral sclerosis (ALS) ( 0.024614601208892 ); hsa05110 Vibrio cholerae infection ( 0.0259415891257939 ); hsa04662 B cell receptor signaling pathway ( 0.0290316555950966 ); hsa04720 Long-term potentiation ( 0.0316733454127016 ); hsa04370 VEGF signaling pathway ( 0.0325524878970817 ); hsa04512 ECM-receptor interaction ( 0.0369375669664392 ); hsa05222 Small cell lung cancer ( 0.0382496409475928 ); hsa04210 Apoptosis ( 0.0391234739484695 ); hsa04660 T cell receptor signaling pathway ( 0.0417407401053659 ); ----------------CARTA-------------- ifngpathway ( 0.0036142725596775 ); at1rpathway ( 0.00541705072317444 ); ifnapathway ( 0.00586729198586233 ); igf1pathway ( 0.010359750035057 ); bcrpathway ( 0.0112560730498985 ); tpopathway ( 0.0130465545567192 ); ngfpathway ( 0.0134937243618438 ); pdgfpathway ( 0.0201796947548332 ); fcer1pathway ( 0.0219558036187589 ); ----------------RBP-------------- ( ); ----------------immu-------------- BCR_signalling_pathway ( 0.0329917930236668 ); TCR_signalling_pathway ( 0.0430469952927979 ); ----------------ARE-------------- ( ); ============================ group2974 ========================= ----------------C2-------------- REACTOME_INTEGRATION_OF_ENERGY_METABOLISM ( 0.00394543867569669 ); BIOCARTA_RANMS_PATHWAY ( 0.00451602439168164 ); REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES ( 0.00451602439168164 ); REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK ( 0.00451602439168164 ); BIOCARTA_AKAP95_PATHWAY ( 0.0049666282130606 ); BIOCARTA_ETC_PATHWAY ( 0.0049666282130606 ); BIOCARTA_LEPTIN_PATHWAY ( 0.0049666282130606 ); BIOCARTA_AKAP13_PATHWAY ( 0.00541705072317444 ); BIOCARTA_AKAPCENTROSOME_PATHWAY ( 0.0063173520649431 ); REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 ( 0.0063173520649431 ); REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE ( 0.00766644583845122 ); REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK ( 0.00766644583845122 ); REACTOME_CITRIC_ACID_CYCLE ( 0.00856493693858129 ); ----------------C3-------------- V$RSRFC4_Q2 ( 0.0023976878225916 ); V$OCT1_02 ( 0.00260052406090237 ); V$POU1F1_Q6 ( 0.00284198014936346 ); V$SP3_Q3 ( 0.00290394467779667 ); V$EVI1_04 ( 0.00299808801576436 ); YATTNATC_UNKNOWN ( 0.00633883924714147 ); CTAWWWATA_V$RSRFC4_Q2 ( 0.00665772062107015 ); ----------------C4-------------- GCM_DPF2 ( 8.40332566582961e-05 ); module_427 ( 0.000862773039915533 ); module_192 ( 0.000880173940990805 ); GCM_RING1 ( 0.000933393457630815 ); GCM_FANCC ( 0.00124286636995826 ); module_279 ( 0.00139175249994872 ); module_257 ( 0.00164217267828789 ); module_334 ( 0.00186192441352196 ); MORF_RAB1A ( 0.00268986764726141 ); MORF_RAC1 ( 0.00328910349998497 ); module_294 ( 0.00811578182091532 ); ----------------C5-------------- COFACTOR_CATABOLIC_PROCESS ( 0.00451602439168164 ); PEROXISOMAL_MEMBRANE ( 0.00541705072317444 ); MICROBODY_MEMBRANE ( 0.00541705072317444 ); PEROXISOMAL_PART ( 0.00586729198586233 ); MICROBODY_PART ( 0.00586729198586233 ); SPINDLE_MICROTUBULE ( 0.00676723102421728 ); PEROXISOME_ORGANIZATION_AND_BIOGENESIS ( 0.00676723102421728 ); AEROBIC_RESPIRATION ( 0.00676723102421728 ); SPINDLE_POLE ( 0.00766644583845122 ); CELLULAR_RESPIRATION ( 0.00856493693858129 ); ----------------GOSLIM-------------- GO:0045273 respiratory chain complex II ( 0.00781282664598833 ); GO:0005148 prolactin receptor binding ( 0.00781282664598833 ); GO:0000104 succinate dehydrogenase activity ( 0.00781282664598833 ); GO:0000090 mitotic anaphase ( 0.00781282664598833 ); GO:0051322 anaphase ( 0.00781282664598833 ); GO:0004691 cAMP-dependent protein kinase activity ( 0.00781282664598833 ); GO:0004690 cyclic nucleotide-dependent protein kinase activity ( 0.00781282664598833 ); GO:0006110 regulation of glycolysis ( 0.00781282664598833 ); GO:0043470 regulation of carbohydrate catabolic process ( 0.00781282664598833 ); GO:0043471 regulation of cellular carbohydrate catabolic process ( 0.00781282664598833 ); GO:0006625 protein targeting to peroxisome ( 0.00781282664598833 ); GO:0007595 lactation ( 0.00781282664598833 ); GO:0043574 peroxisomal transport ( 0.00781282664598833 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00781282664598833 ); GO:0006091 generation of precursor metabolites and energy ( 0.00781282664598833 ); GO:0043467 regulation of generation of precursor metabolites and energy ( 0.00781282664598833 ); GO:0044248 cellular catabolic process ( 0.00781282664598833 ); GO:0005876 spindle microtubule ( 0.00781282664598833 ); GO:0010675 regulation of cellular carbohydrate metabolic process ( 0.00781282664598833 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00781282664598833 ); GO:0006109 regulation of carbohydrate metabolic process ( 0.00781282664598833 ); GO:0007031 peroxisome organization ( 0.00781282664598833 ); ----------------GO-------------- GO:0045273 respiratory chain complex II ( 0.000904658948094661 ); GO:0005148 prolactin receptor binding ( 0.000904658948094661 ); GO:0000104 succinate dehydrogenase activity ( 0.00135671556010364 ); GO:0000090 mitotic anaphase ( 0.00226028338010587 ); GO:0051322 anaphase ( 0.00226028338010587 ); GO:0004691 cAMP-dependent protein kinase activity ( 0.0031631244212782 ); GO:0004690 cyclic nucleotide-dependent protein kinase activity ( 0.00406523919517987 ); GO:0006110 regulation of glycolysis ( 0.00451602439168164 ); GO:0043470 regulation of carbohydrate catabolic process ( 0.0049666282130606 ); GO:0043471 regulation of cellular carbohydrate catabolic process ( 0.0049666282130606 ); GO:0006625 protein targeting to peroxisome ( 0.00586729198586233 ); GO:0007595 lactation ( 0.0063173520649431 ); GO:0043574 peroxisomal transport ( 0.0063173520649431 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00676723102421728 ); GO:0006091 generation of precursor metabolites and energy ( 0.00755979954879157 ); GO:0043467 regulation of generation of precursor metabolites and energy ( 0.00766644583845122 ); GO:0044248 cellular catabolic process ( 0.00780346221198076 ); GO:0005876 spindle microtubule ( 0.00811578182091532 ); GO:0010675 regulation of cellular carbohydrate metabolic process ( 0.00856493693858129 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00901391125515316 ); GO:0006109 regulation of carbohydrate metabolic process ( 0.0094627048343161 ); GO:0007031 peroxisome organization ( 0.0094627048343161 ); ----------------KEGG-------------- hsa00020 Citrate cycle (TCA cycle) ( 0.0139407140653497 ); hsa04920 Adipocytokine signaling pathway ( 0.0294723815936666 ); hsa05012 Parkinson's disease ( 0.0499869951083636 ); ----------------CARTA-------------- trkapathway ( 0.0036142725596775 ); nthipathway ( 0.00811578182091532 ); keratinocytepathway ( 0.0152806032007987 ); fmlppathway ( 0.0184007194661039 ); ----------------RBP-------------- ( 0.0384811641985671 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2992 ========================= ----------------C2-------------- REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS ( 0.00721692892746606 ); REACTOME_BOTULINUM_NEUROTOXICITY ( 0.00811578182091532 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_DDB1 ( 0.000106705129928754 ); MORF_AATF ( 0.00275023226031091 ); MORF_PRKAG1 ( 0.0034902366805755 ); ----------------C5-------------- INTERLEUKIN_8_BIOSYNTHETIC_PROCESS ( 0.00406523919517987 ); DETECTION_OF_BIOTIC_STIMULUS ( 0.00451602439168164 ); PROTEIN_POLYUBIQUITINATION ( 0.0049666282130606 ); INTERLEUKIN_8_PRODUCTION ( 0.0049666282130606 ); CASPASE_REGULATOR_ACTIVITY ( 0.00586729198586233 ); APICAL_PLASMA_MEMBRANE ( 0.0063173520649431 ); APICAL_PART_OF_CELL ( 0.00766644583845122 ); HISTONE_MODIFICATION ( 0.00991131773973564 ); ----------------GOSLIM-------------- GO:0015956 bis(5'-nucleosidyl) oligophosphate metabolic process ( 0.00940144038530285 ); GO:0015958 bis(5'-nucleosidyl) oligophosphate catabolic process ( 0.00940144038530285 ); GO:0015959 diadenosine polyphosphate metabolic process ( 0.00940144038530285 ); GO:0015961 diadenosine polyphosphate catabolic process ( 0.00940144038530285 ); GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity ( 0.00940144038530285 ); GO:0050544 arachidonic acid binding ( 0.00940144038530285 ); GO:0006152 purine nucleoside catabolic process ( 0.00940144038530285 ); GO:0046130 purine ribonucleoside catabolic process ( 0.00940144038530285 ); GO:0050542 icosanoid binding ( 0.00940144038530285 ); GO:0050543 icosatetraenoic acid binding ( 0.00940144038530285 ); GO:0042454 ribonucleoside catabolic process ( 0.00940144038530285 ); GO:0016574 histone ubiquitination ( 0.00940144038530285 ); GO:0009164 nucleoside catabolic process ( 0.00940144038530285 ); GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process ( 0.00940144038530285 ); GO:0034656 nucleobase, nucleoside and nucleotide catabolic process ( 0.00940144038530285 ); GO:0016045 detection of bacterium ( 0.00940144038530285 ); GO:0042228 interleukin-8 biosynthetic process ( 0.00940144038530285 ); GO:0042834 peptidoglycan binding ( 0.00940144038530285 ); GO:0042278 purine nucleoside metabolic process ( 0.00940144038530285 ); GO:0046128 purine ribonucleoside metabolic process ( 0.00940144038530285 ); GO:0031201 SNARE complex ( 0.00940144038530285 ); GO:0008656 caspase activator activity ( 0.00940144038530285 ); GO:0009119 ribonucleoside metabolic process ( 0.00940144038530285 ); GO:0016505 apoptotic protease activator activity ( 0.00940144038530285 ); GO:0009595 detection of biotic stimulus ( 0.00940144038530285 ); GO:0000209 protein polyubiquitination ( 0.00940144038530285 ); GO:0032637 interleukin-8 production ( 0.00940144038530285 ); GO:0016504 protease activator activity ( 0.00940144038530285 ); GO:0030426 growth cone ( 0.00940144038530285 ); GO:0005484 SNAP receptor activity ( 0.00940144038530285 ); GO:0043028 caspase regulator activity ( 0.00940144038530285 ); GO:0030427 site of polarized growth ( 0.00940144038530285 ); ----------------GO-------------- GO:0015956 bis(5'-nucleosidyl) oligophosphate metabolic process ( 0.000452420449404412 ); GO:0015958 bis(5'-nucleosidyl) oligophosphate catabolic process ( 0.000452420449404412 ); GO:0015959 diadenosine polyphosphate metabolic process ( 0.000452420449404412 ); GO:0015961 diadenosine polyphosphate catabolic process ( 0.000452420449404412 ); GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity ( 0.000452420449404412 ); GO:0050544 arachidonic acid binding ( 0.000904658948094661 ); GO:0006152 purine nucleoside catabolic process ( 0.00135671556010364 ); GO:0046130 purine ribonucleoside catabolic process ( 0.00135671556010364 ); GO:0050542 icosanoid binding ( 0.00135671556010364 ); GO:0050543 icosatetraenoic acid binding ( 0.00135671556010364 ); GO:0042454 ribonucleoside catabolic process ( 0.0018085903494427 ); GO:0016574 histone ubiquitination ( 0.00226028338010587 ); GO:0009164 nucleoside catabolic process ( 0.00271179471606597 ); GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process ( 0.0031631244212782 ); GO:0034656 nucleobase, nucleoside and nucleotide catabolic process ( 0.0031631244212782 ); GO:0016045 detection of bacterium ( 0.00406523919517987 ); GO:0042228 interleukin-8 biosynthetic process ( 0.00406523919517987 ); GO:0042834 peptidoglycan binding ( 0.00406523919517987 ); GO:0042278 purine nucleoside metabolic process ( 0.00451602439168164 ); GO:0046128 purine ribonucleoside metabolic process ( 0.00451602439168164 ); GO:0031201 SNARE complex ( 0.00451602439168164 ); GO:0008656 caspase activator activity ( 0.0049666282130606 ); GO:0009119 ribonucleoside metabolic process ( 0.00586729198586233 ); GO:0016505 apoptotic protease activator activity ( 0.00586729198586233 ); GO:0009595 detection of biotic stimulus ( 0.00676723102421728 ); GO:0000209 protein polyubiquitination ( 0.00721692892746606 ); GO:0032637 interleukin-8 production ( 0.00721692892746606 ); GO:0016504 protease activator activity ( 0.00721692892746606 ); GO:0030426 growth cone ( 0.00901391125515316 ); GO:0005484 SNAP receptor activity ( 0.00901391125515316 ); GO:0043028 caspase regulator activity ( 0.00901391125515316 ); GO:0030427 site of polarized growth ( 0.00991131773973564 ); ----------------KEGG-------------- hsa04130 SNARE interactions in vesicular transport ( 0.0170646044739466 ); hsa05120 Epithelial cell signaling in Helicobacter pylori infection ( 0.0299129297636195 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0389700391471244 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2993 ========================= ----------------C2-------------- BIOCARTA_FEEDER_PATHWAY ( 0.00406523919517987 ); REACTOME_OPSINS ( 0.00451602439168164 ); ----------------C3-------------- TNCATNTCCYR_UNKNOWN ( 0.000745724441638595 ); V$HNF4ALPHA_Q6 ( 0.00345632013658443 ); ----------------C4-------------- ( ); ----------------C5-------------- GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY ( 0.00126363508514103 ); CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS ( 0.00128457091305522 ); CARBOHYDRATE_METABOLIC_PROCESS ( 0.00260052406090237 ); PROTEIN_DIMERIZATION_ACTIVITY ( 0.00278065487883624 ); MEMBRANE_PART ( 0.00394548570837542 ); SPHINGOLIPID_BIOSYNTHETIC_PROCESS ( 0.00406523919517987 ); PROTEIN_DEACETYLASE_ACTIVITY ( 0.00406523919517987 ); INTEGRAL_TO_GOLGI_MEMBRANE ( 0.00451602439168164 ); DEACETYLASE_ACTIVITY ( 0.00451602439168164 ); CELLULAR_LIPID_METABOLIC_PROCESS ( 0.00517769341354458 ); N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS ( 0.00541705072317444 ); GLYCOSPHINGOLIPID_METABOLIC_PROCESS ( 0.00541705072317444 ); ANCHORED_TO_MEMBRANE ( 0.00586729198586233 ); ANCHORED_TO_PLASMA_MEMBRANE ( 0.00586729198586233 ); GLUCOSAMINE_METABOLIC_PROCESS ( 0.00586729198586233 ); PROTEIN_TRANSPORTER_ACTIVITY ( 0.0063173520649431 ); INTRINSIC_TO_GOLGI_MEMBRANE ( 0.00676723102421728 ); ENERGY_RESERVE_METABOLIC_PROCESS ( 0.00676723102421728 ); ORGANELLE_MEMBRANE ( 0.00703105823307291 ); GLYCOLIPID_METABOLIC_PROCESS ( 0.00721692892746606 ); ACETYLGLUCOSAMINYLTRANSFERASE_ACTIVITY ( 0.00721692892746606 ); COENZYME_BINDING ( 0.00721692892746606 ); MEMBRANE ( 0.00739129683145716 ); MITOCHONDRIAL_OUTER_MEMBRANE ( 0.00811578182091532 ); HISTONE_DEACETYLASE_COMPLEX ( 0.00811578182091532 ); AMINO_SUGAR_METABOLIC_PROCESS ( 0.00811578182091532 ); LIPID_METABOLIC_PROCESS ( 0.00830930398975994 ); HYDROLASE_ACTIVITY__ACTING_ON_CARBON_NITROGEN__BUT_NOT_PEPTIDE__BONDS__IN_LINEAR_AMIDES ( 0.00856493693858129 ); CYTOPLASM ( 0.00906437838950191 ); COFACTOR_BINDING ( 0.00991131773973564 ); ----------------GOSLIM-------------- GO:0005991 trehalose metabolic process ( ); GO:0005993 trehalose catabolic process ( ); GO:0046352 disaccharide catabolic process ( ); GO:0004555 alpha,alpha-trehalase activity ( ); GO:0015266 protein channel activity ( ); GO:0015927 trehalase activity ( ); GO:0005984 disaccharide metabolic process ( ); GO:0008020 G-protein coupled photoreceptor activity ( ); GO:0006688 glycosphingolipid biosynthetic process ( ); GO:0042752 regulation of circadian rhythm ( ); GO:0009881 photoreceptor activity ( ); GO:0016575 histone deacetylation ( ); GO:0009247 glycolipid biosynthetic process ( ); GO:0046658 anchored to plasma membrane ( ); GO:0018298 protein-chromophore linkage ( ); GO:0008320 protein transmembrane transporter activity ( ); GO:0006476 protein amino acid deacetylation ( ); GO:0006687 glycosphingolipid metabolic process ( ); GO:0004407 histone deacetylase activity ( ); GO:0033558 protein deacetylase activity ( ); GO:0006904 vesicle docking during exocytosis ( ); GO:0030148 sphingolipid biosynthetic process ( ); GO:0048278 vesicle docking ( ); GO:0019213 deacetylase activity ( ); ----------------GO-------------- GO:0005991 trehalose metabolic process ( 0.000452420449404412 ); GO:0005993 trehalose catabolic process ( 0.000452420449404412 ); GO:0046352 disaccharide catabolic process ( 0.000452420449404412 ); GO:0004555 alpha,alpha-trehalase activity ( 0.000452420449404412 ); GO:0015266 protein channel activity ( 0.000452420449404412 ); GO:0015927 trehalase activity ( 0.000452420449404412 ); GO:0005984 disaccharide metabolic process ( 0.00226028338010587 ); GO:0008020 G-protein coupled photoreceptor activity ( 0.00226028338010587 ); GO:0006688 glycosphingolipid biosynthetic process ( 0.00406523919517987 ); GO:0042752 regulation of circadian rhythm ( 0.00451602439168164 ); GO:0009881 photoreceptor activity ( 0.00541705072317444 ); GO:0016575 histone deacetylation ( 0.00586729198586233 ); GO:0009247 glycolipid biosynthetic process ( 0.0063173520649431 ); GO:0046658 anchored to plasma membrane ( 0.0063173520649431 ); GO:0018298 protein-chromophore linkage ( 0.00721692892746606 ); GO:0008320 protein transmembrane transporter activity ( 0.00721692892746606 ); GO:0006476 protein amino acid deacetylation ( 0.00811578182091532 ); GO:0006687 glycosphingolipid metabolic process ( 0.00811578182091532 ); GO:0004407 histone deacetylase activity ( 0.00856493693858129 ); GO:0033558 protein deacetylase activity ( 0.00856493693858129 ); GO:0006904 vesicle docking during exocytosis ( 0.00901391125515316 ); GO:0030148 sphingolipid biosynthetic process ( 0.0094627048343161 ); GO:0048278 vesicle docking ( 0.00991131773973564 ); GO:0019213 deacetylase activity ( 0.00991131773973564 ); ----------------KEGG-------------- ( 0.0192905656663911 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3001 ========================= ----------------C2-------------- BIOCARTA_DEATH_PATHWAY ( 8.96144391409027e-05 ); KEGG_APOPTOSIS ( 0.000667231804029507 ); REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS ( 0.0049666282130606 ); KEGG_RIBOFLAVIN_METABOLISM ( 0.00721692892746606 ); BIOCARTA_MITOCHONDRIA_PATHWAY ( 0.0094627048343161 ); BIOCARTA_CHEMICAL_PATHWAY ( 0.00991131773973564 ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00451602439168164 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0032797 SMN complex ( ); GO:0032266 phosphatidylinositol 3-phosphate binding ( ); GO:0045569 TRAIL binding ( ); GO:0009296 flagellum assembly ( ); GO:0043064 flagellum organization ( ); GO:0032402 melanosome transport ( ); GO:0051904 pigment granule transport ( ); GO:0034464 BBSome ( ); GO:0004726 non-membrane spanning protein tyrosine phosphatase activity ( ); GO:0032400 melanosome localization ( ); GO:0032401 establishment of melanosome localization ( ); GO:0051875 pigment granule localization ( ); GO:0051905 establishment of pigment granule localization ( ); GO:0006917 induction of apoptosis ( ); GO:0012502 induction of programmed cell death ( ); GO:0005932 microtubule basal body ( ); GO:0003993 acid phosphatase activity ( ); GO:0005035 death receptor activity ( ); GO:0007250 activation of NF-kappaB-inducing kinase activity ( ); GO:0008625 induction of apoptosis via death domain receptors ( ); GO:0043065 positive regulation of apoptosis ( ); GO:0043068 positive regulation of programmed cell death ( ); GO:0033059 cellular pigmentation ( ); GO:0001947 heart looping ( ); GO:0042384 cilium assembly ( ); GO:0005737 cytoplasm ( ); ----------------GO-------------- GO:0032797 SMN complex ( 0.000452420449404412 ); GO:0032266 phosphatidylinositol 3-phosphate binding ( 0.000904658948094661 ); GO:0045569 TRAIL binding ( 0.000904658948094661 ); GO:0009296 flagellum assembly ( 0.00271179471606597 ); GO:0043064 flagellum organization ( 0.00271179471606597 ); GO:0032402 melanosome transport ( 0.0031631244212782 ); GO:0051904 pigment granule transport ( 0.0031631244212782 ); GO:0034464 BBSome ( 0.0031631244212782 ); GO:0004726 non-membrane spanning protein tyrosine phosphatase activity ( 0.0031631244212782 ); GO:0032400 melanosome localization ( 0.0036142725596775 ); GO:0032401 establishment of melanosome localization ( 0.0036142725596775 ); GO:0051875 pigment granule localization ( 0.0036142725596775 ); GO:0051905 establishment of pigment granule localization ( 0.0036142725596775 ); GO:0006917 induction of apoptosis ( 0.00383804348619042 ); GO:0012502 induction of programmed cell death ( 0.00387368573788803 ); GO:0005932 microtubule basal body ( 0.00406523919517987 ); GO:0003993 acid phosphatase activity ( 0.00451602439168164 ); GO:0005035 death receptor activity ( 0.00451602439168164 ); GO:0007250 activation of NF-kappaB-inducing kinase activity ( 0.00541705072317444 ); GO:0008625 induction of apoptosis via death domain receptors ( 0.00541705072317444 ); GO:0043065 positive regulation of apoptosis ( 0.00615990101188942 ); GO:0043068 positive regulation of programmed cell death ( 0.00629388062090985 ); GO:0033059 cellular pigmentation ( 0.00676723102421728 ); GO:0001947 heart looping ( 0.00766644583845122 ); GO:0042384 cilium assembly ( 0.00766644583845122 ); GO:0005737 cytoplasm ( 0.00914459950477733 ); ----------------KEGG-------------- hsa04210 Apoptosis ( 0.000682588529830192 ); hsa00740 Riboflavin metabolism ( 0.00676723102421728 ); hsa00361 gamma-Hexachlorocyclohexane degradation ( 0.00811578182091532 ); hsa05040 Huntington's disease ( 0.0143875237307112 ); hsa04520 Adherens junction ( 0.0334309208233938 ); ----------------CARTA-------------- cblpathway ( 0.00135671556010364 ); rarpathway ( 0.00135671556010364 ); sprypathway ( 0.0036142725596775 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3050 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- MITOCHONDRIAL_PART ( 2.71938884780132e-05 ); MITOCHONDRIAL_MATRIX ( 0.000186384415036466 ); MITOCHONDRIAL_LUMEN ( 0.000186384415036466 ); MITOCHONDRION ( 0.000359137569217278 ); PROTEIN_COMPLEX ( 0.0044576617860562 ); HETEROPHILIC_CELL_ADHESION ( 0.00451602439168164 ); ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT ( 0.0049666282130606 ); MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT ( 0.0049666282130606 ); SMALL_RIBOSOMAL_SUBUNIT ( 0.0049666282130606 ); EMBRYO_IMPLANTATION ( 0.00586729198586233 ); MACROMOLECULAR_COMPLEX ( 0.00651324970031246 ); RIBOSOMAL_SUBUNIT ( 0.00901391125515316 ); ORGANELLAR_RIBOSOME ( 0.00991131773973564 ); MITOCHONDRIAL_RIBOSOME ( 0.00991131773973564 ); ----------------GOSLIM-------------- GO:0047323 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity ( 0.00322332320315644 ); GO:0051155 positive regulation of striated muscle cell differentiation ( 0.00322332320315644 ); GO:0033279 ribosomal subunit ( 0.00322332320315644 ); GO:0044429 mitochondrial part ( 0.00322332320315644 ); GO:0043415 positive regulation of skeletal muscle regeneration ( 0.00322332320315644 ); GO:0043416 regulation of skeletal muscle regeneration ( 0.00322332320315644 ); GO:0003735 structural constituent of ribosome ( 0.00322332320315644 ); GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex ( 0.00322332320315644 ); GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex ( 0.00322332320315644 ); GO:0045240 dihydrolipoyl dehydrogenase complex ( 0.00322332320315644 ); GO:0018106 peptidyl-histidine phosphorylation ( 0.00322332320315644 ); GO:0048639 positive regulation of developmental growth ( 0.00322332320315644 ); GO:0051149 positive regulation of muscle cell differentiation ( 0.00322332320315644 ); GO:0051153 regulation of striated muscle cell differentiation ( 0.00322332320315644 ); GO:0045239 tricarboxylic acid cycle enzyme complex ( 0.00322332320315644 ); GO:0018202 peptidyl-histidine modification ( 0.00322332320315644 ); GO:0043403 skeletal muscle regeneration ( 0.00322332320315644 ); GO:0045039 protein import into mitochondrial inner membrane ( 0.00322332320315644 ); GO:0042719 mitochondrial intermembrane space protein transporter complex ( 0.00322332320315644 ); GO:0005759 mitochondrial matrix ( 0.00322332320315644 ); GO:0031980 mitochondrial lumen ( 0.00322332320315644 ); GO:0005840 ribosome ( 0.00322332320315644 ); GO:0007007 inner mitochondrial membrane organization ( 0.00322332320315644 ); GO:0009083 branched chain family amino acid catabolic process ( 0.00322332320315644 ); GO:0048638 regulation of developmental growth ( 0.00322332320315644 ); GO:0044267 cellular protein metabolic process ( 0.00322332320315644 ); GO:0019538 protein metabolic process ( 0.00322332320315644 ); GO:0048286 alveolus development ( 0.00322332320315644 ); GO:0001829 trophectodermal cell differentiation ( 0.00322332320315644 ); GO:0005744 mitochondrial inner membrane presequence translocase complex ( 0.00322332320315644 ); GO:0001825 blastocyst formation ( 0.00322332320315644 ); GO:0016575 histone deacetylation ( 0.00322332320315644 ); GO:0043681 protein import into mitochondrion ( 0.00322332320315644 ); GO:0000155 two-component sensor activity ( 0.00322332320315644 ); GO:0004673 protein histidine kinase activity ( 0.00322332320315644 ); GO:0007566 embryo implantation ( 0.00322332320315644 ); GO:0009081 branched chain family amino acid metabolic process ( 0.00322332320315644 ); GO:0042246 tissue regeneration ( 0.00322332320315644 ); GO:0000314 organellar small ribosomal subunit ( 0.00322332320315644 ); GO:0005763 mitochondrial small ribosomal subunit ( 0.00322332320315644 ); GO:0007157 heterophilic cell adhesion ( 0.00322332320315644 ); GO:0016775 phosphotransferase activity, nitrogenous group as acceptor ( 0.00322332320315644 ); GO:0005739 mitochondrion ( 0.00322332320315644 ); GO:0006476 protein amino acid deacetylation ( 0.00322332320315644 ); GO:0051147 regulation of muscle cell differentiation ( 0.00322332320315644 ); ----------------GO-------------- GO:0047323 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity ( 0.000452420449404412 ); GO:0051155 positive regulation of striated muscle cell differentiation ( 0.000904658948094661 ); GO:0033279 ribosomal subunit ( 0.00102547469159387 ); GO:0044429 mitochondrial part ( 0.00126100174583531 ); GO:0043415 positive regulation of skeletal muscle regeneration ( 0.00135671556010364 ); GO:0043416 regulation of skeletal muscle regeneration ( 0.00135671556010364 ); GO:0003735 structural constituent of ribosome ( 0.00178719372216915 ); GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex ( 0.0018085903494427 ); GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex ( 0.0018085903494427 ); GO:0045240 dihydrolipoyl dehydrogenase complex ( 0.0018085903494427 ); GO:0018106 peptidyl-histidine phosphorylation ( 0.00226028338010587 ); GO:0048639 positive regulation of developmental growth ( 0.00226028338010587 ); GO:0051149 positive regulation of muscle cell differentiation ( 0.00226028338010587 ); GO:0051153 regulation of striated muscle cell differentiation ( 0.00226028338010587 ); GO:0045239 tricarboxylic acid cycle enzyme complex ( 0.00226028338010587 ); GO:0018202 peptidyl-histidine modification ( 0.00271179471606597 ); GO:0043403 skeletal muscle regeneration ( 0.00271179471606597 ); GO:0045039 protein import into mitochondrial inner membrane ( 0.00271179471606597 ); GO:0042719 mitochondrial intermembrane space protein transporter complex ( 0.00271179471606597 ); GO:0005759 mitochondrial matrix ( 0.00299808801576436 ); GO:0031980 mitochondrial lumen ( 0.00299808801576436 ); GO:0005840 ribosome ( 0.0030297877360064 ); GO:0007007 inner mitochondrial membrane organization ( 0.0036142725596775 ); GO:0009083 branched chain family amino acid catabolic process ( 0.0036142725596775 ); GO:0048638 regulation of developmental growth ( 0.0036142725596775 ); GO:0044267 cellular protein metabolic process ( 0.00371337077333803 ); GO:0019538 protein metabolic process ( 0.0038565605134359 ); GO:0048286 alveolus development ( 0.00451602439168164 ); GO:0001829 trophectodermal cell differentiation ( 0.0049666282130606 ); GO:0005744 mitochondrial inner membrane presequence translocase complex ( 0.0049666282130606 ); GO:0001825 blastocyst formation ( 0.00586729198586233 ); GO:0016575 histone deacetylation ( 0.00586729198586233 ); GO:0043681 protein import into mitochondrion ( 0.00586729198586233 ); GO:0000155 two-component sensor activity ( 0.00586729198586233 ); GO:0004673 protein histidine kinase activity ( 0.00586729198586233 ); GO:0007566 embryo implantation ( 0.0063173520649431 ); GO:0009081 branched chain family amino acid metabolic process ( 0.0063173520649431 ); GO:0042246 tissue regeneration ( 0.0063173520649431 ); GO:0000314 organellar small ribosomal subunit ( 0.00721692892746606 ); GO:0005763 mitochondrial small ribosomal subunit ( 0.00721692892746606 ); GO:0007157 heterophilic cell adhesion ( 0.00766644583845122 ); GO:0016775 phosphotransferase activity, nitrogenous group as acceptor ( 0.00766644583845122 ); GO:0005739 mitochondrion ( 0.00780346221198076 ); GO:0006476 protein amino acid deacetylation ( 0.00811578182091532 ); GO:0051147 regulation of muscle cell differentiation ( 0.00856493693858129 ); ----------------KEGG-------------- ( 0.0321130053809839 ); ----------------CARTA-------------- ( 0.00901391125515316 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00583781891322799 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00715111082192027 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3067 ========================= ----------------C2-------------- ( ); ----------------C3-------------- TCCGTCC,MIR-184 ( 0.00451602439168164 ); AGCGCAG,MIR-191 ( 0.00451602439168164 ); ----------------C4-------------- ( 0.0094627048343161 ); ----------------C5-------------- PROTEIN_EXPORT_FROM_NUCLEUS ( 0.00451602439168164 ); PROTEIN_TRANSPORTER_ACTIVITY ( 0.0063173520649431 ); ----------------GOSLIM-------------- GO:0051014 actin filament severing ( ); GO:0004427 inorganic diphosphatase activity ( ); GO:0043623 cellular protein complex assembly ( ); GO:0000059 protein import into nucleus, docking ( ); GO:0006611 protein export from nucleus ( ); GO:0006461 protein complex assembly ( ); GO:0070271 protein complex biogenesis ( ); ----------------GO-------------- GO:0051014 actin filament severing ( 0.0018085903494427 ); GO:0004427 inorganic diphosphatase activity ( 0.0018085903494427 ); GO:0043623 cellular protein complex assembly ( 0.0025417652725801 ); GO:0000059 protein import into nucleus, docking ( 0.00766644583845122 ); GO:0006611 protein export from nucleus ( 0.00856493693858129 ); GO:0006461 protein complex assembly ( 0.00996096014954709 ); GO:0070271 protein complex biogenesis ( 0.00996096014954709 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3116 ========================= ----------------C2-------------- KEGG_APOPTOSIS ( 6.65912955301257e-06 ); BIOCARTA_BAD_PATHWAY ( 5.88018820021398e-05 ); REACTOME_AXON_GUIDANCE ( 0.00220276951175339 ); BIOCARTA_P35ALZHEIMERS_PATHWAY ( 0.0049666282130606 ); BIOCARTA_IL3_PATHWAY ( 0.00676723102421728 ); BIOCARTA_P53_PATHWAY ( 0.00721692892746606 ); REACTOME_CELLEXTRACELLULAR_MATRIX_INTERACTIONS ( 0.00721692892746606 ); BIOCARTA_UCALPAIN_PATHWAY ( 0.00766644583845122 ); BIOCARTA_MITOCHONDRIA_PATHWAY ( 0.0094627048343161 ); BIOCARTA_CHEMICAL_PATHWAY ( 0.00991131773973564 ); BIOCARTA_CERAMIDE_PATHWAY ( 0.00991131773973564 ); BIOCARTA_P53HYPOXIA_PATHWAY ( 0.00991131773973564 ); ----------------C3-------------- V$LFA1_Q6 ( 6.37909686749749e-05 ); YNGTTNNNATT_UNKNOWN ( 0.00602726818430267 ); V$PAX3_01 ( 0.00676723102421728 ); ----------------C4-------------- ( 0.0094627048343161 ); ----------------C5-------------- RESPONSE_TO_TOXIN ( 0.00451602439168164 ); APOPTOTIC_MITOCHONDRIAL_CHANGES ( 0.0049666282130606 ); REGULATION_OF_NEURON_APOPTOSIS ( 0.00541705072317444 ); DNA_FRAGMENTATION_DURING_APOPTOSIS ( 0.00586729198586233 ); RESPIRATORY_GASEOUS_EXCHANGE ( 0.0063173520649431 ); SENSORY_ORGAN_DEVELOPMENT ( 0.0063173520649431 ); VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX ( 0.00676723102421728 ); REGULATION_OF_MEMBRANE_POTENTIAL ( 0.00676723102421728 ); NEURON_APOPTOSIS ( 0.00766644583845122 ); CELL_STRUCTURE_DISASSEMBLY_DURING_APOPTOSIS ( 0.00811578182091532 ); VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY ( 0.00811578182091532 ); APOPTOTIC_NUCLEAR_CHANGES ( 0.00856493693858129 ); INTERLEUKIN_RECEPTOR_ACTIVITY ( 0.00856493693858129 ); PROTEIN_HOMOOLIGOMERIZATION ( 0.00991131773973564 ); ----------------GOSLIM-------------- GO:0032976 release of matrix enzymes from mitochondria ( 0.0060443107508953 ); GO:0046670 positive regulation of retinal cell programmed cell death ( 0.00904853663517908 ); GO:0046674 induction of retinal programmed cell death ( 0.0060443107508953 ); GO:0005757 mitochondrial permeability transition pore complex ( 0.00904853663517908 ); GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex ( 0.0060443107508953 ); GO:0005262 calcium channel activity ( 0.00904853663517908 ); GO:0010248 establishment or maintenance of transmembrane electrochemical gradient ( 0.0060443107508953 ); GO:0030264 nuclear fragmentation during apoptosis ( 0.00904853663517908 ); GO:0043653 mitochondrial fragmentation during apoptosis ( 0.0060443107508953 ); GO:0004912 interleukin-3 receptor activity ( 0.00904853663517908 ); GO:0004914 interleukin-5 receptor activity ( 0.0060443107508953 ); GO:0008332 low voltage-gated calcium channel activity ( 0.00904853663517908 ); GO:0019978 interleukin-3 binding ( 0.0060443107508953 ); GO:0019980 interleukin-5 binding ( 0.00904853663517908 ); GO:0051400 BH domain binding ( 0.0060443107508953 ); GO:0051434 BH3 domain binding ( 0.00904853663517908 ); GO:0006922 cleavage of lamin ( 0.0060443107508953 ); GO:0006923 cleavage of cytoskeletal proteins during apoptosis ( 0.00904853663517908 ); GO:0006927 transformed cell apoptosis ( 0.0060443107508953 ); GO:0006816 calcium ion transport ( 0.00904853663517908 ); GO:0008053 mitochondrial fusion ( 0.0060443107508953 ); GO:0043497 regulation of protein heterodimerization activity ( 0.00904853663517908 ); GO:0010623 developmental programmed cell death ( 0.0060443107508953 ); GO:0043496 regulation of protein homodimerization activity ( 0.00904853663517908 ); GO:0046666 retinal cell programmed cell death ( 0.0060443107508953 ); GO:0046668 regulation of retinal cell programmed cell death ( 0.00904853663517908 ); GO:0015674 di-, tri-valent inorganic cation transport ( 0.0060443107508953 ); GO:0001783 B cell apoptosis ( 0.00904853663517908 ); GO:0005244 voltage-gated ion channel activity ( 0.0060443107508953 ); GO:0022832 voltage-gated channel activity ( 0.00904853663517908 ); GO:0008634 negative regulation of survival gene product expression ( 0.0060443107508953 ); GO:0008635 activation of caspase activity by cytochrome c ( 0.00904853663517908 ); GO:0043525 positive regulation of neuron apoptosis ( 0.0060443107508953 ); GO:0019904 protein domain specific binding ( 0.00904853663517908 ); GO:0007379 segment specification ( 0.0060443107508953 ); GO:0070227 lymphocyte apoptosis ( 0.00904853663517908 ); GO:0005261 cation channel activity ( 0.0060443107508953 ); GO:0005509 calcium ion binding ( 0.00904853663517908 ); GO:0051881 regulation of mitochondrial membrane potential ( 0.0060443107508953 ); GO:0001836 release of cytochrome c from mitochondria ( 0.00904853663517908 ); GO:0048284 organelle fusion ( 0.0060443107508953 ); GO:0004198 calcium-dependent cysteine-type endopeptidase activity ( 0.00904853663517908 ); GO:0006309 DNA fragmentation during apoptosis ( 0.0060443107508953 ); GO:0046873 metal ion transmembrane transporter activity ( 0.00904853663517908 ); GO:0022836 gated channel activity ( 0.0060443107508953 ); GO:0045884 regulation of survival gene product expression ( 0.00904853663517908 ); GO:0043393 regulation of protein binding ( 0.0060443107508953 ); GO:0006921 cell structure disassembly during apoptosis ( 0.00904853663517908 ); GO:0001756 somitogenesis ( 0.0060443107508953 ); GO:0005891 voltage-gated calcium channel complex ( 0.00904853663517908 ); GO:0030262 apoptotic nuclear changes ( 0.0060443107508953 ); ----------------GO-------------- GO:0032976 release of matrix enzymes from mitochondria ( 0.000452420449404412 ); GO:0046670 positive regulation of retinal cell programmed cell death ( 0.000452420449404412 ); GO:0046674 induction of retinal programmed cell death ( 0.000452420449404412 ); GO:0005757 mitochondrial permeability transition pore complex ( 0.000452420449404412 ); GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex ( 0.000452420449404412 ); GO:0005262 calcium channel activity ( 0.00045748766468051 ); GO:0010248 establishment or maintenance of transmembrane electrochemical gradient ( 0.000904658948094661 ); GO:0030264 nuclear fragmentation during apoptosis ( 0.000904658948094661 ); GO:0043653 mitochondrial fragmentation during apoptosis ( 0.000904658948094661 ); GO:0004912 interleukin-3 receptor activity ( 0.000904658948094661 ); GO:0004914 interleukin-5 receptor activity ( 0.000904658948094661 ); GO:0008332 low voltage-gated calcium channel activity ( 0.000904658948094661 ); GO:0019978 interleukin-3 binding ( 0.000904658948094661 ); GO:0019980 interleukin-5 binding ( 0.000904658948094661 ); GO:0051400 BH domain binding ( 0.000904658948094661 ); GO:0051434 BH3 domain binding ( 0.000904658948094661 ); GO:0006922 cleavage of lamin ( 0.00135671556010364 ); GO:0006923 cleavage of cytoskeletal proteins during apoptosis ( 0.00135671556010364 ); GO:0006927 transformed cell apoptosis ( 0.00135671556010364 ); GO:0006816 calcium ion transport ( 0.00159515151234164 ); GO:0008053 mitochondrial fusion ( 0.0018085903494427 ); GO:0043497 regulation of protein heterodimerization activity ( 0.0018085903494427 ); GO:0010623 developmental programmed cell death ( 0.00226028338010587 ); GO:0043496 regulation of protein homodimerization activity ( 0.00226028338010587 ); GO:0046666 retinal cell programmed cell death ( 0.00226028338010587 ); GO:0046668 regulation of retinal cell programmed cell death ( 0.00226028338010587 ); GO:0015674 di-, tri-valent inorganic cation transport ( 0.0023976878225916 ); GO:0001783 B cell apoptosis ( 0.00271179471606597 ); GO:0005244 voltage-gated ion channel activity ( 0.00293516636890903 ); GO:0022832 voltage-gated channel activity ( 0.00293516636890903 ); GO:0008634 negative regulation of survival gene product expression ( 0.0031631244212782 ); GO:0008635 activation of caspase activity by cytochrome c ( 0.0031631244212782 ); GO:0043525 positive regulation of neuron apoptosis ( 0.0036142725596775 ); GO:0019904 protein domain specific binding ( 0.00405423742536105 ); GO:0007379 segment specification ( 0.00406523919517987 ); GO:0070227 lymphocyte apoptosis ( 0.00406523919517987 ); GO:0005261 cation channel activity ( 0.00505548787484375 ); GO:0005509 calcium ion binding ( 0.0052924857557881 ); GO:0051881 regulation of mitochondrial membrane potential ( 0.00586729198586233 ); GO:0001836 release of cytochrome c from mitochondria ( 0.0063173520649431 ); GO:0048284 organelle fusion ( 0.0063173520649431 ); GO:0004198 calcium-dependent cysteine-type endopeptidase activity ( 0.0063173520649431 ); GO:0006309 DNA fragmentation during apoptosis ( 0.00721692892746606 ); GO:0046873 metal ion transmembrane transporter activity ( 0.00722127064343387 ); GO:0022836 gated channel activity ( 0.00726919165571675 ); GO:0045884 regulation of survival gene product expression ( 0.00766644583845122 ); GO:0043393 regulation of protein binding ( 0.00811578182091532 ); GO:0006921 cell structure disassembly during apoptosis ( 0.00901391125515316 ); GO:0001756 somitogenesis ( 0.0094627048343161 ); GO:0005891 voltage-gated calcium channel complex ( 0.0094627048343161 ); GO:0030262 apoptotic nuclear changes ( 0.00991131773973564 ); ----------------KEGG-------------- hsa04210 Apoptosis ( 6.89259460003546e-06 ); hsa05040 Huntington's disease ( 0.0143875237307112 ); hsa04930 Type II diabetes mellitus ( 0.0184007194661039 ); hsa05014 Amyotrophic lateral sclerosis (ALS) ( 0.024614601208892 ); hsa04115 p53 signaling pathway ( 0.0299129297636195 ); hsa05210 Colorectal cancer ( 0.0373751016407096 ); ----------------CARTA-------------- g2pathway ( 6.34911303092269e-05 ); il7pathway ( 0.00586729198586233 ); il6pathway ( 0.0063173520649431 ); integrinpathway ( 0.00991131773973564 ); nfatpathway ( 0.0166188737055817 ); mapkpathway ( 0.0201796947548332 ); ----------------RBP-------------- ( 0.0322650324378669 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3130 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$POU3F2_02 ( 0.00332223095937783 ); AAAYWAACM_V$HFH4_01 ( 0.00335551646983232 ); ----------------C4-------------- ( 0.00106348804876391 ); ----------------C5-------------- INTERCALATED_DISC ( 0.00406523919517987 ); NEUROPEPTIDE_RECEPTOR_ACTIVITY ( 0.00991131773973564 ); ----------------GOSLIM-------------- GO:0002432 granuloma formation ( ); GO:0043320 natural killer cell degranulation ( ); GO:0004995 tachykinin receptor activity ( ); GO:0002544 chronic inflammatory response ( ); GO:0007217 tachykinin receptor signaling pathway ( ); GO:0005154 epidermal growth factor receptor binding ( ); GO:0051707 response to other organism ( ); GO:0002467 germinal center formation ( ); GO:0030057 desmosome ( ); GO:0043299 leukocyte degranulation ( ); GO:0045055 regulated secretory pathway ( ); GO:0009607 response to biotic stimulus ( ); GO:0002228 natural killer cell mediated immunity ( ); GO:0042267 natural killer cell mediated cytotoxicity ( ); GO:0001909 leukocyte mediated cytotoxicity ( ); GO:0030101 natural killer cell activation ( ); ----------------GO-------------- GO:0002432 granuloma formation ( 0.000452420449404412 ); GO:0043320 natural killer cell degranulation ( 0.000452420449404412 ); GO:0004995 tachykinin receptor activity ( 0.00135671556010364 ); GO:0002544 chronic inflammatory response ( 0.00226028338010587 ); GO:0007217 tachykinin receptor signaling pathway ( 0.0036142725596775 ); GO:0005154 epidermal growth factor receptor binding ( 0.0036142725596775 ); GO:0051707 response to other organism ( 0.00376722799877577 ); GO:0002467 germinal center formation ( 0.00406523919517987 ); GO:0030057 desmosome ( 0.00406523919517987 ); GO:0043299 leukocyte degranulation ( 0.0049666282130606 ); GO:0045055 regulated secretory pathway ( 0.00676723102421728 ); GO:0009607 response to biotic stimulus ( 0.0075109985759033 ); GO:0002228 natural killer cell mediated immunity ( 0.00766644583845122 ); GO:0042267 natural killer cell mediated cytotoxicity ( 0.00766644583845122 ); GO:0001909 leukocyte mediated cytotoxicity ( 0.00856493693858129 ); GO:0030101 natural killer cell activation ( 0.00901391125515316 ); ----------------KEGG-------------- ( 0.0382496409475928 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3151 ========================= ----------------C2-------------- KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS ( 0.000794867391044177 ); KEGG_INSULIN_SIGNALING_PATHWAY ( 0.00161857950603624 ); KEGG_LIMONENE_AND_PINENE_DEGRADATION ( 0.00406523919517987 ); REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION ( 0.00451602439168164 ); REACTOME_PECAM1_INTERACTIONS ( 0.00541705072317444 ); REACTOME_RNA_POLYMERASE_III_CHAIN_ELONGATION ( 0.00541705072317444 ); REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS ( 0.0063173520649431 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION ( 0.00766644583845122 ); REACTOME_MICRORNA_BIOGENESIS ( 0.00811578182091532 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE ( 0.00901391125515316 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER ( 0.00901391125515316 ); REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_TERMINATION ( 0.0094627048343161 ); KEGG_BETA_ALANINE_METABOLISM ( 0.00991131773973564 ); KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS ( 0.00991131773973564 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER ( 0.00991131773973564 ); ----------------C3-------------- ( 0.00707839036563591 ); ----------------C4-------------- MORF_AP2M1 ( 0.00335551646983232 ); module_44 ( 0.00830930398975994 ); module_249 ( 0.0094627048343161 ); module_295 ( 0.0094627048343161 ); ----------------C5-------------- ( 0.0049666282130606 ); ----------------GOSLIM-------------- GO:0016507 fatty acid beta-oxidation multienzyme complex ( ); GO:0016508 long-chain-enoyl-CoA hydratase activity ( ); GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity ( ); GO:0003985 acetyl-CoA C-acetyltransferase activity ( ); GO:0003002 regionalization ( ); GO:0003988 acetyl-CoA C-acyltransferase activity ( ); GO:0016453 C-acetyltransferase activity ( ); GO:0060017 parathyroid gland development ( ); GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity ( ); GO:0004300 enoyl-CoA hydratase activity ( ); GO:0007389 pattern specification process ( ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( ); GO:0046030 inositol trisphosphate phosphatase activity ( ); GO:0030742 GTP-dependent protein binding ( ); GO:0007032 endosome organization ( ); GO:0009954 proximal/distal pattern formation ( ); GO:0048538 thymus development ( ); GO:0000062 acyl-CoA binding ( ); GO:0016408 C-acyltransferase activity ( ); GO:0006635 fatty acid beta-oxidation ( ); ----------------GO-------------- GO:0016507 fatty acid beta-oxidation multienzyme complex ( 0.000452420449404412 ); GO:0016508 long-chain-enoyl-CoA hydratase activity ( 0.000452420449404412 ); GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity ( 0.000452420449404412 ); GO:0003985 acetyl-CoA C-acetyltransferase activity ( 0.00135671556010364 ); GO:0003002 regionalization ( 0.00161857950603624 ); GO:0003988 acetyl-CoA C-acyltransferase activity ( 0.0018085903494427 ); GO:0016453 C-acetyltransferase activity ( 0.0018085903494427 ); GO:0060017 parathyroid gland development ( 0.00271179471606597 ); GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity ( 0.00271179471606597 ); GO:0004300 enoyl-CoA hydratase activity ( 0.00271179471606597 ); GO:0007389 pattern specification process ( 0.00284198014936346 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.0031631244212782 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.0031631244212782 ); GO:0030742 GTP-dependent protein binding ( 0.0036142725596775 ); GO:0007032 endosome organization ( 0.00451602439168164 ); GO:0009954 proximal/distal pattern formation ( 0.00541705072317444 ); GO:0048538 thymus development ( 0.00541705072317444 ); GO:0000062 acyl-CoA binding ( 0.00541705072317444 ); GO:0016408 C-acyltransferase activity ( 0.00541705072317444 ); GO:0006635 fatty acid beta-oxidation ( 0.00856493693858129 ); ----------------KEGG-------------- hsa04910 Insulin signaling pathway ( 0.00159515151234164 ); hsa00930 Caprolactam degradation ( 0.0031631244212782 ); hsa00062 Fatty acid elongation in mitochondria ( 0.00451602439168164 ); hsa00632 Benzoate degradation via CoA ligation ( 0.0063173520649431 ); hsa00903 Limonene and pinene degradation ( 0.00811578182091532 ); hsa01040 Biosynthesis of unsaturated fatty acids ( 0.0094627048343161 ); hsa00410 beta-Alanine metabolism ( 0.0108080017839093 ); hsa03020 RNA polymerase ( 0.0112560730498985 ); hsa00640 Propanoate metabolism ( 0.0157268731323761 ); hsa00650 Butanoate metabolism ( 0.0170646044739466 ); hsa00071 Fatty acid metabolism ( 0.0206239905401618 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0206239905401618 ); hsa00310 Lysine degradation ( 0.0223993834296551 ); hsa00380 Tryptophan metabolism ( 0.0223993834296551 ); hsa04662 B cell receptor signaling pathway ( 0.0290316555950966 ); hsa05211 Renal cell carcinoma ( 0.0307934928688005 ); hsa05220 Chronic myeloid leukemia ( 0.0329917930236668 ); hsa04070 Phosphatidylinositol signaling system ( 0.0338698713588964 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0338698713588964 ); hsa04012 ErbB signaling pathway ( 0.0382496409475928 ); hsa00240 Pyrimidine metabolism ( 0.0404329002179002 ); ----------------CARTA-------------- notchpathway ( 0.0031631244212782 ); hespathway ( 0.00586729198586233 ); ps1pathway ( 0.0117039638966141 ); ----------------RBP-------------- SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00583781891322799 ); ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.00651907937347988 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0446077680891479 ); ----------------immu-------------- ( 0.0329917930236668 ); ----------------ARE-------------- ( ); ============================ group3184 ========================= ----------------C2-------------- KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION ( 1.50149004798342e-05 ); KEGG_INOSITOL_PHOSPHATE_METABOLISM ( 0.000257213250063813 ); KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM ( 0.000509630660703222 ); KEGG_CALCIUM_SIGNALING_PATHWAY ( 0.00271996981039946 ); ----------------C3-------------- V$RORA2_01 ( 0.00110217472129003 ); AGTCTAG,MIR-151 ( 0.00901391125515316 ); ----------------C4-------------- ( ); ----------------C5-------------- PHOSPHORUS_OXYGEN_LYASE_ACTIVITY ( 0.00451602439168164 ); CYCLASE_ACTIVITY ( 0.0049666282130606 ); NEUROTRANSMITTER_SECRETION ( 0.00586729198586233 ); TUBE_MORPHOGENESIS ( 0.00676723102421728 ); REGULATED_SECRETORY_PATHWAY ( 0.00676723102421728 ); REGULATION_OF_MEMBRANE_POTENTIAL ( 0.00676723102421728 ); REGULATION_OF_ACTION_POTENTIAL ( 0.00766644583845122 ); TUBE_DEVELOPMENT ( 0.00811578182091532 ); DETECTION_OF_CHEMICAL_STIMULUS ( 0.00811578182091532 ); CYTOSOLIC_PART ( 0.00991131773973564 ); ----------------GOSLIM-------------- GO:0035150 regulation of tube size ( 0.00576605511618585 ); GO:0050880 regulation of blood vessel size ( 0.00576605511618585 ); GO:0003018 vascular process in circulatory system ( 0.00576605511618585 ); GO:0052551 response to defense-related nitric oxide production by other organism during symbiotic interaction ( 0.00576605511618585 ); GO:0052564 response to immune response of other organism during symbiotic interaction ( 0.00576605511618585 ); GO:0052565 response to defense-related host nitric oxide production ( 0.00576605511618585 ); GO:0052572 response to host immune response ( 0.00576605511618585 ); GO:0060087 relaxation of vascular smooth muscle ( 0.00576605511618585 ); GO:0030825 positive regulation of cGMP metabolic process ( 0.00576605511618585 ); GO:0030828 positive regulation of cGMP biosynthetic process ( 0.00576605511618585 ); GO:0008074 guanylate cyclase complex, soluble ( 0.00576605511618585 ); GO:0045986 negative regulation of smooth muscle contraction ( 0.00576605511618585 ); GO:0052173 response to defenses of other organism during symbiotic interaction ( 0.00576605511618585 ); GO:0052200 response to host defenses ( 0.00576605511618585 ); GO:0004687 myosin light chain kinase activity ( 0.00576605511618585 ); GO:0030823 regulation of cGMP metabolic process ( 0.00576605511618585 ); GO:0030826 regulation of cGMP biosynthetic process ( 0.00576605511618585 ); GO:0044057 regulation of system process ( 0.00576605511618585 ); GO:0045932 negative regulation of muscle contraction ( 0.00576605511618585 ); GO:0003013 circulatory system process ( 0.00576605511618585 ); GO:0008015 blood circulation ( 0.00576605511618585 ); GO:0030801 positive regulation of cyclic nucleotide metabolic process ( 0.00576605511618585 ); GO:0030804 positive regulation of cyclic nucleotide biosynthetic process ( 0.00576605511618585 ); GO:0030810 positive regulation of nucleotide biosynthetic process ( 0.00576605511618585 ); GO:0045981 positive regulation of nucleotide metabolic process ( 0.00576605511618585 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.00576605511618585 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.00576605511618585 ); GO:0004383 guanylate cyclase activity ( 0.00576605511618585 ); GO:0005513 detection of calcium ion ( 0.00576605511618585 ); GO:0046928 regulation of neurotransmitter secretion ( 0.00576605511618585 ); GO:0015269 calcium-activated potassium channel activity ( 0.00576605511618585 ); GO:0007263 nitric oxide mediated signal transduction ( 0.00576605511618585 ); GO:0022839 ion gated channel activity ( 0.00576605511618585 ); GO:0006182 cGMP biosynthetic process ( 0.00576605511618585 ); GO:0046068 cGMP metabolic process ( 0.00576605511618585 ); GO:0005227 calcium activated cation channel activity ( 0.00576605511618585 ); GO:0051588 regulation of neurotransmitter transport ( 0.00576605511618585 ); GO:0019229 regulation of vasoconstriction ( 0.00576605511618585 ); GO:0042578 phosphoric ester hydrolase activity ( 0.00576605511618585 ); GO:0016849 phosphorus-oxygen lyase activity ( 0.00576605511618585 ); GO:0009975 cyclase activity ( 0.00576605511618585 ); GO:0006940 regulation of smooth muscle contraction ( 0.00576605511618585 ); ----------------GO-------------- GO:0035150 regulation of tube size ( 0.000266856761005348 ); GO:0050880 regulation of blood vessel size ( 0.000266856761005348 ); GO:0003018 vascular process in circulatory system ( 0.000276675389676741 ); GO:0052551 response to defense-related nitric oxide production by other organism during symbiotic interaction ( 0.000452420449404412 ); GO:0052564 response to immune response of other organism during symbiotic interaction ( 0.000452420449404412 ); GO:0052565 response to defense-related host nitric oxide production ( 0.000452420449404412 ); GO:0052572 response to host immune response ( 0.000452420449404412 ); GO:0060087 relaxation of vascular smooth muscle ( 0.000452420449404412 ); GO:0030825 positive regulation of cGMP metabolic process ( 0.000904658948094661 ); GO:0030828 positive regulation of cGMP biosynthetic process ( 0.000904658948094661 ); GO:0008074 guanylate cyclase complex, soluble ( 0.000904658948094661 ); GO:0045986 negative regulation of smooth muscle contraction ( 0.00135671556010364 ); GO:0052173 response to defenses of other organism during symbiotic interaction ( 0.00135671556010364 ); GO:0052200 response to host defenses ( 0.00135671556010364 ); GO:0004687 myosin light chain kinase activity ( 0.00135671556010364 ); GO:0030823 regulation of cGMP metabolic process ( 0.00226028338010587 ); GO:0030826 regulation of cGMP biosynthetic process ( 0.00226028338010587 ); GO:0044057 regulation of system process ( 0.0025417652725801 ); GO:0045932 negative regulation of muscle contraction ( 0.00271179471606597 ); GO:0003013 circulatory system process ( 0.0030297877360064 ); GO:0008015 blood circulation ( 0.0030297877360064 ); GO:0030801 positive regulation of cyclic nucleotide metabolic process ( 0.0031631244212782 ); GO:0030804 positive regulation of cyclic nucleotide biosynthetic process ( 0.0031631244212782 ); GO:0030810 positive regulation of nucleotide biosynthetic process ( 0.0031631244212782 ); GO:0045981 positive regulation of nucleotide metabolic process ( 0.0031631244212782 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.0031631244212782 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.0031631244212782 ); GO:0004383 guanylate cyclase activity ( 0.0036142725596775 ); GO:0005513 detection of calcium ion ( 0.00406523919517987 ); GO:0046928 regulation of neurotransmitter secretion ( 0.0049666282130606 ); GO:0015269 calcium-activated potassium channel activity ( 0.00541705072317444 ); GO:0007263 nitric oxide mediated signal transduction ( 0.00586729198586233 ); GO:0022839 ion gated channel activity ( 0.00586729198586233 ); GO:0006182 cGMP biosynthetic process ( 0.0063173520649431 ); GO:0046068 cGMP metabolic process ( 0.00676723102421728 ); GO:0005227 calcium activated cation channel activity ( 0.00676723102421728 ); GO:0051588 regulation of neurotransmitter transport ( 0.00721692892746606 ); GO:0019229 regulation of vasoconstriction ( 0.00766644583845122 ); GO:0042578 phosphoric ester hydrolase activity ( 0.0081062394640593 ); GO:0016849 phosphorus-oxygen lyase activity ( 0.00856493693858129 ); GO:0009975 cyclase activity ( 0.00901391125515316 ); GO:0006940 regulation of smooth muscle contraction ( 0.0094627048343161 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.000203036661786702 ); hsa04070 Phosphatidylinositol signaling system ( 0.000509630660703222 ); hsa04020 Calcium signaling pathway ( 0.00275023226031091 ); hsa04730 Long-term depression ( 0.0329917930236668 ); hsa04540 Gap junction ( 0.0426117528710088 ); ----------------CARTA-------------- p53pathway ( 0.0036142725596775 ); gata3pathway ( 0.00676723102421728 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3191 ========================= ----------------C2-------------- REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA ( 0.00901391125515316 ); REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12 ( 0.0094627048343161 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00974014999593728 ); ----------------GOSLIM-------------- GO:0031593 polyubiquitin binding ( ); GO:0006703 estrogen biosynthetic process ( ); GO:0050327 testosterone 17-beta-dehydrogenase activity ( ); GO:0051117 ATPase binding ( ); GO:0008209 androgen metabolic process ( ); GO:0008210 estrogen metabolic process ( ); GO:0004303 estradiol 17-beta-dehydrogenase activity ( ); GO:0004886 retinoid-X receptor activity ( ); GO:0010861 thyroid hormone receptor activator activity ( ); GO:0030375 thyroid hormone receptor coactivator activity ( ); GO:0042974 retinoic acid receptor binding ( ); GO:0003708 retinoic acid receptor activity ( ); GO:0030546 receptor activator activity ( ); GO:0003712 transcription cofactor activity ( ); GO:0042809 vitamin D receptor binding ( ); GO:0043130 ubiquitin binding ( ); GO:0032182 small conjugating protein binding ( ); GO:0005544 calcium-dependent phospholipid binding ( ); ----------------GO-------------- GO:0031593 polyubiquitin binding ( 0.000904658948094661 ); GO:0006703 estrogen biosynthetic process ( 0.0018085903494427 ); GO:0050327 testosterone 17-beta-dehydrogenase activity ( 0.0018085903494427 ); GO:0051117 ATPase binding ( 0.0031631244212782 ); GO:0008209 androgen metabolic process ( 0.00406523919517987 ); GO:0008210 estrogen metabolic process ( 0.00406523919517987 ); GO:0004303 estradiol 17-beta-dehydrogenase activity ( 0.00451602439168164 ); GO:0004886 retinoid-X receptor activity ( 0.00451602439168164 ); GO:0010861 thyroid hormone receptor activator activity ( 0.00451602439168164 ); GO:0030375 thyroid hormone receptor coactivator activity ( 0.00451602439168164 ); GO:0042974 retinoic acid receptor binding ( 0.00541705072317444 ); GO:0003708 retinoic acid receptor activity ( 0.00586729198586233 ); GO:0030546 receptor activator activity ( 0.00586729198586233 ); GO:0003712 transcription cofactor activity ( 0.00765784018961607 ); GO:0042809 vitamin D receptor binding ( 0.00811578182091532 ); GO:0043130 ubiquitin binding ( 0.00811578182091532 ); GO:0032182 small conjugating protein binding ( 0.0094627048343161 ); GO:0005544 calcium-dependent phospholipid binding ( 0.00991131773973564 ); ----------------KEGG-------------- ( 0.0179555272908964 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.00494788982376985 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00576210053021998 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00583781891322799 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00715111082192027 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3192 ========================= ----------------C2-------------- KEGG_GLYCOSAMINOGLYCAN_DEGRADATION ( 0.0094627048343161 ); REACTOME_SHCMEDIATED_CASCADE ( 0.0094627048343161 ); ----------------C3-------------- V$TFIIA_Q6 ( 0.00362747634804666 ); CTTTGA_V$LEF1_Q2 ( 0.00596824135404136 ); TACGGGT,MIR-99A,MIR-100,MIR-99B ( 0.0094627048343161 ); ----------------C4-------------- module_390 ( 0.0036142725596775 ); module_543 ( 0.00721692892746606 ); module_414 ( 0.00766644583845122 ); ----------------C5-------------- ( 0.00766644583845122 ); ----------------GOSLIM-------------- GO:0003940 L-iduronidase activity ( 0.000698125661825648 ); GO:0019834 phospholipase A2 inhibitor activity ( 0.00229152655167058 ); GO:0005984 disaccharide metabolic process ( 0.00589598519776553 ); GO:0005007 fibroblast growth factor receptor activity ( 0.0081062394640593 ); GO:0007216 metabotropic glutamate receptor signaling pathway ( 0.000698125661825648 ); GO:0004859 phospholipase inhibitor activity ( 0.00229152655167058 ); GO:0001501 skeletal system development ( 0.00589598519776553 ); GO:0055102 lipase inhibitor activity ( 0.0081062394640593 ); GO:0007215 glutamate signaling pathway ( 0.000698125661825648 ); GO:0007040 lysosome organization ( 0.00229152655167058 ); GO:0007033 vacuole organization ( 0.00589598519776553 ); GO:0005544 calcium-dependent phospholipid binding ( 0.0081062394640593 ); ----------------GO-------------- GO:0003940 L-iduronidase activity ( 0.000452420449404412 ); GO:0019834 phospholipase A2 inhibitor activity ( 0.00135671556010364 ); GO:0005984 disaccharide metabolic process ( 0.00226028338010587 ); GO:0005007 fibroblast growth factor receptor activity ( 0.00226028338010587 ); GO:0007216 metabotropic glutamate receptor signaling pathway ( 0.00271179471606597 ); GO:0004859 phospholipase inhibitor activity ( 0.0049666282130606 ); GO:0001501 skeletal system development ( 0.00602726818430267 ); GO:0055102 lipase inhibitor activity ( 0.0063173520649431 ); GO:0007215 glutamate signaling pathway ( 0.00856493693858129 ); GO:0007040 lysosome organization ( 0.00901391125515316 ); GO:0007033 vacuole organization ( 0.00991131773973564 ); GO:0005544 calcium-dependent phospholipid binding ( 0.00991131773973564 ); ----------------KEGG-------------- hsa00531 Glycosaminoglycan degradation ( 0.00811578182091532 ); hsa01032 Glycan structures - degradation ( 0.0139407140653497 ); hsa05219 Bladder cancer ( 0.0188457322368472 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3195 ========================= ----------------C2-------------- BIOCARTA_LECTIN_PATHWAY ( 0.0049666282130606 ); REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT ( 0.0063173520649431 ); REACTOME_ZINC_TRANSPORTATION ( 0.00766644583845122 ); BIOCARTA_COMP_PATHWAY ( 0.00811578182091532 ); REACTOME_COMPLEMENT_CASCADE ( 0.0094627048343161 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ENDOPEPTIDASE_ACTIVITY ( 0.00112177024619528 ); PEPTIDASE_ACTIVITY ( 0.00251262731449257 ); TUBE_MORPHOGENESIS ( 0.00676723102421728 ); EMBRYONIC_MORPHOGENESIS ( 0.00766644583845122 ); TUBE_DEVELOPMENT ( 0.00811578182091532 ); EXTRACELLULAR_REGION_PART ( 0.00909134362253378 ); ----------------GOSLIM-------------- GO:0007443 Malpighian tubule morphogenesis ( ); GO:0048619 embryonic hindgut morphogenesis ( ); GO:0007442 hindgut morphogenesis ( ); GO:0001867 complement activation, lectin pathway ( ); GO:0007439 ectodermal gut development ( ); GO:0048567 ectodermal gut morphogenesis ( ); GO:0005385 zinc ion transmembrane transporter activity ( ); GO:0046928 regulation of neurotransmitter secretion ( ); GO:0048546 digestive tract morphogenesis ( ); GO:0048547 gut morphogenesis ( ); GO:0055123 digestive system development ( ); GO:0051588 regulation of neurotransmitter transport ( ); GO:0019905 syntaxin binding ( ); GO:0000149 SNARE binding ( ); GO:0046915 transition metal ion transmembrane transporter activity ( ); GO:0048565 gut development ( ); ----------------GO-------------- GO:0007443 Malpighian tubule morphogenesis ( 0.000452420449404412 ); GO:0048619 embryonic hindgut morphogenesis ( 0.000452420449404412 ); GO:0007442 hindgut morphogenesis ( 0.00135671556010364 ); GO:0001867 complement activation, lectin pathway ( 0.0018085903494427 ); GO:0007439 ectodermal gut development ( 0.00226028338010587 ); GO:0048567 ectodermal gut morphogenesis ( 0.00226028338010587 ); GO:0005385 zinc ion transmembrane transporter activity ( 0.00451602439168164 ); GO:0046928 regulation of neurotransmitter secretion ( 0.0049666282130606 ); GO:0048546 digestive tract morphogenesis ( 0.0049666282130606 ); GO:0048547 gut morphogenesis ( 0.0049666282130606 ); GO:0055123 digestive system development ( 0.0049666282130606 ); GO:0051588 regulation of neurotransmitter transport ( 0.00721692892746606 ); GO:0019905 syntaxin binding ( 0.00721692892746606 ); GO:0000149 SNARE binding ( 0.0094627048343161 ); GO:0046915 transition metal ion transmembrane transporter activity ( 0.0094627048343161 ); GO:0048565 gut development ( 0.00991131773973564 ); ----------------KEGG-------------- ( 0.0303533001677417 ); ----------------CARTA-------------- nthipathway ( 0.00811578182091532 ); keratinocytepathway ( 0.0152806032007987 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3250 ========================= ----------------C2-------------- ( 0.00766644583845122 ); ----------------C3-------------- V$FOXM1_01 ( 0.00296654752082416 ); CGCTGCT,MIR-503 ( 0.00811578182091532 ); ----------------C4-------------- ( 0.00676723102421728 ); ----------------C5-------------- AMYLOID_PRECURSOR_PROTEIN_METABOLIC_PROCESS ( 0.00451602439168164 ); POSITIVE_REGULATION_OF_PROTEIN_SECRETION ( 0.0049666282130606 ); COLLAGEN_BINDING ( 0.00541705072317444 ); CARBOXY_LYASE_ACTIVITY ( 0.0063173520649431 ); SYNAPTOGENESIS ( 0.00811578182091532 ); CARBON_CARBON_LYASE_ACTIVITY ( 0.00811578182091532 ); POSITIVE_REGULATION_OF_SECRETION ( 0.00856493693858129 ); REGULATION_OF_PROTEIN_SECRETION ( 0.0094627048343161 ); ----------------GOSLIM-------------- GO:0032223 negative regulation of synaptic transmission, cholinergic ( ); GO:0001760 aminocarboxymuconate-semialdehyde decarboxylase activity ( ); GO:0003990 acetylcholinesterase activity ( ); GO:0005082 receptor signaling protein tyrosine phosphatase signaling protein activity ( ); GO:0001507 acetylcholine catabolic process in synaptic cleft ( ); GO:0006581 acetylcholine catabolic process ( ); GO:0032222 regulation of synaptic transmission, cholinergic ( ); GO:0004104 cholinesterase activity ( ); GO:0043237 laminin-1 binding ( ); GO:0008291 acetylcholine metabolic process ( ); GO:0008268 receptor signaling protein tyrosine kinase signaling protein activity ( ); GO:0046874 quinolinate metabolic process ( ); GO:0042135 neurotransmitter catabolic process ( ); GO:0042439 ethanolamine and derivative metabolic process ( ); GO:0050805 negative regulation of synaptic transmission ( ); GO:0043236 laminin binding ( ); GO:0051970 negative regulation of transmission of nerve impulse ( ); GO:0002076 osteoblast development ( ); GO:0031645 negative regulation of neurological system process ( ); GO:0050840 extracellular matrix binding ( ); GO:0001540 beta-amyloid binding ( ); GO:0005605 basal lamina ( ); GO:0007268 synaptic transmission ( ); GO:0007271 synaptic transmission, cholinergic ( ); GO:0042402 biogenic amine catabolic process ( ); GO:0042982 amyloid precursor protein metabolic process ( ); GO:0016254 preassembly of GPI anchor in ER membrane ( ); GO:0042133 neurotransmitter metabolic process ( ); GO:0019226 transmission of nerve impulse ( ); GO:0042219 amino acid derivative catabolic process ( ); GO:0042166 acetylcholine binding ( ); ----------------GO-------------- GO:0032223 negative regulation of synaptic transmission, cholinergic ( 0.000452420449404412 ); GO:0001760 aminocarboxymuconate-semialdehyde decarboxylase activity ( 0.000452420449404412 ); GO:0003990 acetylcholinesterase activity ( 0.000452420449404412 ); GO:0005082 receptor signaling protein tyrosine phosphatase signaling protein activity ( 0.000452420449404412 ); GO:0001507 acetylcholine catabolic process in synaptic cleft ( 0.000904658948094661 ); GO:0006581 acetylcholine catabolic process ( 0.000904658948094661 ); GO:0032222 regulation of synaptic transmission, cholinergic ( 0.000904658948094661 ); GO:0004104 cholinesterase activity ( 0.000904658948094661 ); GO:0043237 laminin-1 binding ( 0.000904658948094661 ); GO:0008291 acetylcholine metabolic process ( 0.00135671556010364 ); GO:0008268 receptor signaling protein tyrosine kinase signaling protein activity ( 0.00135671556010364 ); GO:0046874 quinolinate metabolic process ( 0.00226028338010587 ); GO:0042135 neurotransmitter catabolic process ( 0.00271179471606597 ); GO:0042439 ethanolamine and derivative metabolic process ( 0.00271179471606597 ); GO:0050805 negative regulation of synaptic transmission ( 0.00271179471606597 ); GO:0043236 laminin binding ( 0.00271179471606597 ); GO:0051970 negative regulation of transmission of nerve impulse ( 0.0031631244212782 ); GO:0002076 osteoblast development ( 0.0036142725596775 ); GO:0031645 negative regulation of neurological system process ( 0.00406523919517987 ); GO:0050840 extracellular matrix binding ( 0.00406523919517987 ); GO:0001540 beta-amyloid binding ( 0.0049666282130606 ); GO:0005605 basal lamina ( 0.00541705072317444 ); GO:0007268 synaptic transmission ( 0.00585252469637144 ); GO:0007271 synaptic transmission, cholinergic ( 0.00586729198586233 ); GO:0042402 biogenic amine catabolic process ( 0.0063173520649431 ); GO:0042982 amyloid precursor protein metabolic process ( 0.00676723102421728 ); GO:0016254 preassembly of GPI anchor in ER membrane ( 0.00721692892746606 ); GO:0042133 neurotransmitter metabolic process ( 0.00721692892746606 ); GO:0019226 transmission of nerve impulse ( 0.00770707963433731 ); GO:0042219 amino acid derivative catabolic process ( 0.00811578182091532 ); GO:0042166 acetylcholine binding ( 0.00901391125515316 ); ----------------KEGG-------------- hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis ( 0.010359750035057 ); hsa00380 Tryptophan metabolism ( 0.0223993834296551 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0281496698608656 ); hsa00564 Glycerophospholipid metabolism ( 0.0290316555950966 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3329 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_552 ( 0.00811578182091532 ); GNF2_MATK ( 0.00991131773973564 ); ----------------C5-------------- HISTONE_METHYLTRANSFERASE_ACTIVITY ( 0.0049666282130606 ); INSOLUBLE_FRACTION ( 0.0063173520649431 ); PROTEIN_METHYLTRANSFERASE_ACTIVITY ( 0.0063173520649431 ); DNA_DAMAGE_CHECKPOINT ( 0.00901391125515316 ); ----------------GOSLIM-------------- GO:0031574 S-M checkpoint ( ); GO:0019781 NEDD8 activating enzyme activity ( ); GO:0035098 ESC/E(Z) complex ( ); GO:0045116 protein neddylation ( ); GO:0000293 ferric-chelate reductase activity ( ); GO:0004500 dopamine beta-monooxygenase activity ( ); GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor ( ); GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ( ); GO:0008508 bile acid:sodium symporter activity ( ); GO:0031519 PcG protein complex ( ); GO:0004726 non-membrane spanning protein tyrosine phosphatase activity ( ); GO:0016722 oxidoreductase activity, oxidizing metal ions ( ); GO:0034708 methyltransferase complex ( ); GO:0035097 histone methyltransferase complex ( ); GO:0008641 small protein activating enzyme activity ( ); GO:0006548 histidine catabolic process ( ); GO:0009077 histidine family amino acid catabolic process ( ); GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity ( ); GO:0015125 bile acid transmembrane transporter activity ( ); GO:0006547 histidine metabolic process ( ); GO:0009075 histidine family amino acid metabolic process ( ); GO:0016411 acylglycerol O-acyltransferase activity ( ); GO:0003824 catalytic activity ( ); GO:0008028 monocarboxylic acid transmembrane transporter activity ( ); GO:0006406 mRNA export from nucleus ( ); GO:0005343 organic acid:sodium symporter activity ( ); ----------------GO-------------- GO:0031574 S-M checkpoint ( 0.000452420449404412 ); GO:0019781 NEDD8 activating enzyme activity ( 0.000452420449404412 ); GO:0035098 ESC/E(Z) complex ( 0.000904658948094661 ); GO:0045116 protein neddylation ( 0.00135671556010364 ); GO:0000293 ferric-chelate reductase activity ( 0.00135671556010364 ); GO:0004500 dopamine beta-monooxygenase activity ( 0.0018085903494427 ); GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor ( 0.0018085903494427 ); GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ( 0.00226028338010587 ); GO:0008508 bile acid:sodium symporter activity ( 0.00271179471606597 ); GO:0031519 PcG protein complex ( 0.0031631244212782 ); GO:0004726 non-membrane spanning protein tyrosine phosphatase activity ( 0.0031631244212782 ); GO:0016722 oxidoreductase activity, oxidizing metal ions ( 0.0031631244212782 ); GO:0034708 methyltransferase complex ( 0.0036142725596775 ); GO:0035097 histone methyltransferase complex ( 0.0036142725596775 ); GO:0008641 small protein activating enzyme activity ( 0.0036142725596775 ); GO:0006548 histidine catabolic process ( 0.00406523919517987 ); GO:0009077 histidine family amino acid catabolic process ( 0.00406523919517987 ); GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity ( 0.00406523919517987 ); GO:0015125 bile acid transmembrane transporter activity ( 0.00451602439168164 ); GO:0006547 histidine metabolic process ( 0.0049666282130606 ); GO:0009075 histidine family amino acid metabolic process ( 0.0049666282130606 ); GO:0016411 acylglycerol O-acyltransferase activity ( 0.00676723102421728 ); GO:0003824 catalytic activity ( 0.00824026926762367 ); GO:0008028 monocarboxylic acid transmembrane transporter activity ( 0.00901391125515316 ); GO:0006406 mRNA export from nucleus ( 0.00991131773973564 ); GO:0005343 organic acid:sodium symporter activity ( 0.00991131773973564 ); ----------------KEGG-------------- hsa00624 1- and 2-Methylnaphthalene degradation ( 0.00541705072317444 ); hsa00632 Benzoate degradation via CoA ligation ( 0.0063173520649431 ); hsa00960 Alkaloid biosynthesis II ( 0.0063173520649431 ); hsa00903 Limonene and pinene degradation ( 0.00811578182091532 ); hsa00360 Phenylalanine metabolism ( 0.00901391125515316 ); hsa00565 Ether lipid metabolism ( 0.0143875237307112 ); hsa00350 Tyrosine metabolism ( 0.0201796947548332 ); hsa00561 Glycerolipid metabolism ( 0.0223993834296551 ); hsa00564 Glycerophospholipid metabolism ( 0.0290316555950966 ); ----------------CARTA-------------- nfkbpathway ( 0.00766644583845122 ); ngfpathway ( 0.0134937243618438 ); pdgfpathway ( 0.0201796947548332 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.00651907937347988 ); QKI_PAR-CLIP_(Hafner_2010) ( 0.00963059423250543 ); ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 0.0305797516721658 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0446077680891479 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3349 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- NUCLEOLUS ( 0.00120183076327647 ); RIBOSOME_BIOGENESIS_AND_ASSEMBLY ( 0.0063173520649431 ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( 0.00271179471606597 ); ----------------KEGG-------------- hsa05218 Melanoma ( 0.0316733454127016 ); hsa05215 Prostate cancer ( 0.0391234739484695 ); hsa04540 Gap junction ( 0.0426117528710088 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0322650324378669 ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_C5 ( 0.0106334199713651 ); ARE_ALL ( 0.0275740251231838 ); ============================ group3352 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00656586796622094 ); ----------------C4-------------- MORF_MYL3 ( 0.000396202376772652 ); MORF_RUNX1 ( 0.00168985407686042 ); MORF_PSMF1 ( 0.00201580993884121 ); MORF_PPP2R5B ( 0.00217557277817385 ); MORF_IL13 ( 0.00390948417314326 ); MORF_IL16 ( 0.00416443660054718 ); MORF_MSH3 ( 0.00427603307098318 ); MORF_BRCA1 ( 0.00493465577716064 ); MORF_NOS2A ( 0.00615990101188942 ); MORF_ARL3 ( 0.00693683658118826 ); MORF_ERCC4 ( 0.00760874679057373 ); ----------------C5-------------- PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00406523919517987 ); INTEGRAL_TO_GOLGI_MEMBRANE ( 0.00451602439168164 ); RIBONUCLEOTIDE_METABOLIC_PROCESS ( 0.0063173520649431 ); INTRINSIC_TO_GOLGI_MEMBRANE ( 0.00676723102421728 ); ----------------GOSLIM-------------- GO:0006256 UDP catabolic process ( ); GO:0009140 pyrimidine nucleoside diphosphate catabolic process ( ); GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process ( ); GO:0009195 pyrimidine ribonucleoside diphosphate catabolic process ( ); GO:0009222 pyrimidine ribonucleotide catabolic process ( ); GO:0046048 UDP metabolic process ( ); GO:0045134 uridine-diphosphatase activity ( ); GO:0009138 pyrimidine nucleoside diphosphate metabolic process ( ); GO:0009191 ribonucleoside diphosphate catabolic process ( ); GO:0009134 nucleoside diphosphate catabolic process ( ); GO:0009185 ribonucleoside diphosphate metabolic process ( ); GO:0017110 nucleoside-diphosphatase activity ( ); GO:0006244 pyrimidine nucleotide catabolic process ( ); GO:0009132 nucleoside diphosphate metabolic process ( ); GO:0009261 ribonucleotide catabolic process ( ); GO:0030514 negative regulation of BMP signaling pathway ( ); GO:0009218 pyrimidine ribonucleotide metabolic process ( ); GO:0030510 regulation of BMP signaling pathway ( ); GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ( ); ----------------GO-------------- GO:0006256 UDP catabolic process ( 0.000452420449404412 ); GO:0009140 pyrimidine nucleoside diphosphate catabolic process ( 0.000452420449404412 ); GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process ( 0.000452420449404412 ); GO:0009195 pyrimidine ribonucleoside diphosphate catabolic process ( 0.000452420449404412 ); GO:0009222 pyrimidine ribonucleotide catabolic process ( 0.000452420449404412 ); GO:0046048 UDP metabolic process ( 0.000452420449404412 ); GO:0045134 uridine-diphosphatase activity ( 0.000452420449404412 ); GO:0009138 pyrimidine nucleoside diphosphate metabolic process ( 0.000904658948094661 ); GO:0009191 ribonucleoside diphosphate catabolic process ( 0.00135671556010364 ); GO:0009134 nucleoside diphosphate catabolic process ( 0.0018085903494427 ); GO:0009185 ribonucleoside diphosphate metabolic process ( 0.0018085903494427 ); GO:0017110 nucleoside-diphosphatase activity ( 0.00271179471606597 ); GO:0006244 pyrimidine nucleotide catabolic process ( 0.0036142725596775 ); GO:0009132 nucleoside diphosphate metabolic process ( 0.00406523919517987 ); GO:0009261 ribonucleotide catabolic process ( 0.0049666282130606 ); GO:0030514 negative regulation of BMP signaling pathway ( 0.00541705072317444 ); GO:0009218 pyrimidine ribonucleotide metabolic process ( 0.00766644583845122 ); GO:0030510 regulation of BMP signaling pathway ( 0.00856493693858129 ); GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ( 0.0094627048343161 ); ----------------KEGG-------------- ( 0.0404329002179002 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.00409081503559177 ); ============================ group777 ========================= ----------------C2-------------- BIOCARTA_ERYTH_PATHWAY ( 0.00601743275876021 ); BIOCARTA_STEM_PATHWAY ( 0.00601743275876021 ); REACTOME_DUAL_INCISION_REACTION_IN_GG_NER ( 0.00801619055166014 ); BIOCARTA_DC_PATHWAY ( 0.00881470841537757 ); ----------------C3-------------- V$GATA_C ( 0.0027595384667992 ); SCGGAAGY_V$ELK1_02 ( 0.00290036617249277 ); TCANNTGAY_V$SREBP1_01 ( 0.00823656524957225 ); ----------------C4-------------- ( ); ----------------C5-------------- REGULATION_OF_CELLULAR_PH ( 0.00401515195112445 ); REGULATION_OF_CHROMOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00401515195112445 ); CERAMIDE_METABOLIC_PROCESS ( 0.00401515195112445 ); AMYLOID_PRECURSOR_PROTEIN_METABOLIC_PROCESS ( 0.00401515195112445 ); LYSOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00441589020915356 ); CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS ( 0.00441589020915356 ); SPHINGOID_METABOLIC_PROCESS ( 0.00441589020915356 ); ENDODEOXYRIBONUCLEASE_ACTIVITY ( 0.00441589020915356 ); GLYCOPROTEIN_CATABOLIC_PROCESS ( 0.0048164873763562 ); VACUOLE_ORGANIZATION_AND_BIOGENESIS ( 0.0048164873763562 ); GLYCOSPHINGOLIPID_METABOLIC_PROCESS ( 0.0048164873763562 ); GOLGI_STACK ( 0.00521694349531354 ); REGULATION_OF_PH ( 0.00521694349531354 ); MONOVALENT_INORGANIC_CATION_HOMEOSTASIS ( 0.00561725860859519 ); SYNAPTIC_VESICLE ( 0.00601743275876021 ); GLYCOLIPID_METABOLIC_PROCESS ( 0.00641746598835713 ); NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS ( 0.00681735833992403 ); EARLY_ENDOSOME ( 0.00721710985598756 ); NEURON_PROJECTION ( 0.00801619055166014 ); NUCLEOTIDE_EXCISION_REPAIR ( 0.00801619055166014 ); TRANS_GOLGI_NETWORK ( 0.00841551981626976 ); DAMAGED_DNA_BINDING ( 0.00841551981626976 ); DEOXYRIBONUCLEASE_ACTIVITY ( 0.00841551981626976 ); DNA_CATABOLIC_PROCESS ( 0.00921375639145716 ); INTRINSIC_TO_ENDOPLASMIC_RETICULUM_MEMBRANE ( 0.00961266378697145 ); INTEGRAL_TO_ENDOPLASMIC_RETICULUM_MEMBRANE ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0001575 globoside metabolic process ( 0.00153579275624659 ); GO:0005129 granulocyte macrophage colony-stimulating factor receptor binding ( 0.00292278815263296 ); GO:0051052 regulation of DNA metabolic process ( 0.00153579275624659 ); GO:0045918 negative regulation of cytolysis ( 0.00292278815263296 ); GO:0005128 erythropoietin receptor binding ( 0.00153579275624659 ); GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion ( 0.00292278815263296 ); GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion ( 0.00153579275624659 ); GO:0006681 galactosylceramide metabolic process ( 0.00292278815263296 ); GO:0015809 arginine transport ( 0.00153579275624659 ); GO:0019374 galactolipid metabolic process ( 0.00292278815263296 ); GO:0000014 single-stranded DNA specific endodeoxyribonuclease activity ( 0.00153579275624659 ); GO:0006678 glucosylceramide metabolic process ( 0.00292278815263296 ); GO:0007042 lysosomal lumen acidification ( 0.00153579275624659 ); GO:0042268 regulation of cytolysis ( 0.00292278815263296 ); GO:0000109 nucleotide-excision repair complex ( 0.00153579275624659 ); GO:0015802 basic amino acid transport ( 0.00292278815263296 ); GO:0033683 nucleotide-excision repair, DNA incision ( 0.00153579275624659 ); GO:0043011 myeloid dendritic cell differentiation ( 0.00292278815263296 ); GO:0000737 DNA catabolic process, endonucleolytic ( 0.00153579275624659 ); GO:0006677 glycosylceramide metabolic process ( 0.00292278815263296 ); GO:0001773 myeloid dendritic cell activation ( 0.00153579275624659 ); GO:0006312 mitotic recombination ( 0.00292278815263296 ); GO:0032205 negative regulation of telomere maintenance ( 0.00153579275624659 ); GO:0051452 intracellular pH reduction ( 0.00292278815263296 ); GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein ( 0.00153579275624659 ); GO:0042987 amyloid precursor protein catabolic process ( 0.00292278815263296 ); GO:0045851 pH reduction ( 0.00153579275624659 ); GO:0045885 positive regulation of survival gene product expression ( 0.00292278815263296 ); GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein ( 0.00153579275624659 ); GO:0006684 sphingomyelin metabolic process ( 0.00292278815263296 ); GO:0016236 macroautophagy ( 0.00153579275624659 ); GO:0042506 tyrosine phosphorylation of Stat5 protein ( 0.00292278815263296 ); GO:0051453 regulation of intracellular pH ( 0.00153579275624659 ); GO:0043066 negative regulation of apoptosis ( 0.00292278815263296 ); GO:0043069 negative regulation of programmed cell death ( 0.00153579275624659 ); GO:0030641 regulation of cellular pH ( 0.00292278815263296 ); GO:0032204 regulation of telomere maintenance ( 0.00153579275624659 ); GO:0010744 positive regulation of foam cell differentiation ( 0.00292278815263296 ); GO:0030004 cellular monovalent inorganic cation homeostasis ( 0.00153579275624659 ); GO:0032845 negative regulation of homeostatic process ( 0.00292278815263296 ); GO:0042982 amyloid precursor protein metabolic process ( 0.00153579275624659 ); GO:0006516 glycoprotein catabolic process ( 0.00292278815263296 ); GO:0045651 positive regulation of macrophage differentiation ( 0.00153579275624659 ); GO:0045884 regulation of survival gene product expression ( 0.00292278815263296 ); GO:0004520 endodeoxyribonuclease activity ( 0.00153579275624659 ); GO:0006687 glycosphingolipid metabolic process ( 0.00292278815263296 ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( 0.00153579275624659 ); GO:0045740 positive regulation of DNA replication ( 0.00292278815263296 ); GO:0000784 nuclear chromosome, telomeric region ( 0.00153579275624659 ); GO:0007040 lysosome organization ( 0.00292278815263296 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00153579275624659 ); GO:0000718 nucleotide-excision repair, DNA damage removal ( 0.00292278815263296 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.00153579275624659 ); GO:0005901 caveola ( 0.00292278815263296 ); GO:0007033 vacuole organization ( 0.00153579275624659 ); GO:0009267 cellular response to starvation ( 0.00292278815263296 ); GO:0010743 regulation of foam cell differentiation ( 0.00153579275624659 ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( 0.00292278815263296 ); GO:0033044 regulation of chromosome organization ( 0.00153579275624659 ); GO:0019835 cytolysis ( 0.00292278815263296 ); ----------------GO-------------- GO:0001575 globoside metabolic process ( 0.00040215151058165 ); GO:0005129 granulocyte macrophage colony-stimulating factor receptor binding ( 0.00040215151058165 ); GO:0051052 regulation of DNA metabolic process ( 0.000451284889538312 ); GO:0045918 negative regulation of cytolysis ( 0.000804161503941581 ); GO:0005128 erythropoietin receptor binding ( 0.000804161503941581 ); GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion ( 0.00120603002276776 ); GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion ( 0.00120603002276776 ); GO:0006681 galactosylceramide metabolic process ( 0.00120603002276776 ); GO:0015809 arginine transport ( 0.00120603002276776 ); GO:0019374 galactolipid metabolic process ( 0.00120603002276776 ); GO:0000014 single-stranded DNA specific endodeoxyribonuclease activity ( 0.00120603002276776 ); GO:0006678 glucosylceramide metabolic process ( 0.00160775710973693 ); GO:0007042 lysosomal lumen acidification ( 0.00160775710973693 ); GO:0042268 regulation of cytolysis ( 0.00160775710973693 ); GO:0000109 nucleotide-excision repair complex ( 0.00160775710973693 ); GO:0015802 basic amino acid transport ( 0.00200934280751575 ); GO:0033683 nucleotide-excision repair, DNA incision ( 0.00241078715875964 ); GO:0043011 myeloid dendritic cell differentiation ( 0.00241078715875964 ); GO:0000737 DNA catabolic process, endonucleolytic ( 0.00281209020611339 ); GO:0006677 glycosylceramide metabolic process ( 0.00281209020611339 ); GO:0001773 myeloid dendritic cell activation ( 0.00321325199221201 ); GO:0006312 mitotic recombination ( 0.00321325199221201 ); GO:0032205 negative regulation of telomere maintenance ( 0.00321325199221201 ); GO:0051452 intracellular pH reduction ( 0.00321325199221201 ); GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein ( 0.00361427255967794 ); GO:0042987 amyloid precursor protein catabolic process ( 0.00361427255967794 ); GO:0045851 pH reduction ( 0.00361427255967794 ); GO:0045885 positive regulation of survival gene product expression ( 0.00361427255967794 ); GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein ( 0.00401515195112445 ); GO:0006684 sphingomyelin metabolic process ( 0.00441589020915356 ); GO:0016236 macroautophagy ( 0.00441589020915356 ); GO:0042506 tyrosine phosphorylation of Stat5 protein ( 0.00441589020915356 ); GO:0051453 regulation of intracellular pH ( 0.00441589020915356 ); GO:0043066 negative regulation of apoptosis ( 0.00462597276813825 ); GO:0043069 negative regulation of programmed cell death ( 0.004799035529206 ); GO:0030641 regulation of cellular pH ( 0.0048164873763562 ); GO:0032204 regulation of telomere maintenance ( 0.0048164873763562 ); GO:0010744 positive regulation of foam cell differentiation ( 0.00521694349531354 ); GO:0030004 cellular monovalent inorganic cation homeostasis ( 0.00601743275876021 ); GO:0032845 negative regulation of homeostatic process ( 0.00601743275876021 ); GO:0042982 amyloid precursor protein metabolic process ( 0.00601743275876021 ); GO:0006516 glycoprotein catabolic process ( 0.00681735833992403 ); GO:0045651 positive regulation of macrophage differentiation ( 0.00681735833992403 ); GO:0045884 regulation of survival gene product expression ( 0.00681735833992403 ); GO:0004520 endodeoxyribonuclease activity ( 0.00681735833992403 ); GO:0006687 glycosphingolipid metabolic process ( 0.00721710985598756 ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( 0.00721710985598756 ); GO:0045740 positive regulation of DNA replication ( 0.0076167205790646 ); GO:0000784 nuclear chromosome, telomeric region ( 0.0076167205790646 ); GO:0007040 lysosome organization ( 0.00801619055166014 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00801619055166014 ); GO:0000718 nucleotide-excision repair, DNA damage removal ( 0.00841551981626976 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.00841551981626976 ); GO:0005901 caveola ( 0.00841551981626976 ); GO:0007033 vacuole organization ( 0.00881470841537757 ); GO:0009267 cellular response to starvation ( 0.00881470841537757 ); GO:0010743 regulation of foam cell differentiation ( 0.00881470841537757 ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( 0.00881470841537757 ); GO:0033044 regulation of chromosome organization ( 0.00921375639145716 ); GO:0019835 cytolysis ( 0.00961266378697145 ); ----------------KEGG-------------- hsa03420 Nucleotide excision repair ( 0.0171652503919058 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0301631779479862 ); hsa04640 Hematopoietic cell lineage ( 0.0332914446808504 ); hsa04660 T cell receptor signaling pathway ( 0.0371893596581885 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0383560491912923 ); ----------------ARE-------------- ( 0.00681735833992403 ); ============================ group1963 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN ( 0.00401515195112445 ); REGULATION_OF_JAK_STAT_CASCADE ( 0.0048164873763562 ); TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN ( 0.00521694349531354 ); POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION ( 0.00521694349531354 ); MYELOID_LEUKOCYTE_DIFFERENTIATION ( 0.00601743275876021 ); REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION ( 0.00721710985598756 ); POSITIVE_REGULATION_OF_PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 0.00801619055166014 ); CYTOKINE_AND_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY ( 0.00881470841537757 ); ----------------GOSLIM-------------- GO:0043031 negative regulation of macrophage activation ( ); GO:0030224 monocyte differentiation ( ); GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein ( ); GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein ( ); GO:0043030 regulation of macrophage activation ( ); GO:0042506 tyrosine phosphorylation of Stat5 protein ( ); GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0042503 tyrosine phosphorylation of Stat3 protein ( ); GO:0042116 macrophage activation ( ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( ); GO:0046427 positive regulation of JAK-STAT cascade ( ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( ); ----------------GO-------------- GO:0043031 negative regulation of macrophage activation ( 0.000804161503941581 ); GO:0030224 monocyte differentiation ( 0.00281209020611339 ); GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein ( 0.00361427255967794 ); GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ( 0.00401515195112445 ); GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein ( 0.00401515195112445 ); GO:0043030 regulation of macrophage activation ( 0.00401515195112445 ); GO:0042506 tyrosine phosphorylation of Stat5 protein ( 0.00441589020915356 ); GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein ( 0.00561725860859519 ); GO:0042503 tyrosine phosphorylation of Stat3 protein ( 0.00601743275876021 ); GO:0042116 macrophage activation ( 0.00681735833992403 ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( 0.00721710985598756 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00801619055166014 ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( 0.00881470841537757 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2510 ========================= ----------------C2-------------- ( 0.00490431186380371 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- NICOTINIC_ACETYLCHOLINE_GATED_RECEPTOR_CHANNEL_COMPLEX ( 0.00441589020915356 ); NICOTINIC_ACETYLCHOLINE_ACTIVATED_CATION_SELECTIVE_CHANNEL_ACTIVITY ( 0.00441589020915356 ); VITAMIN_BINDING ( 0.0048164873763562 ); EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY ( 0.00841551981626976 ); EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY ( 0.00841551981626976 ); ----------------GOSLIM-------------- GO:0004736 pyruvate carboxylase activity ( ); GO:0004997 thyrotropin-releasing hormone receptor activity ( ); GO:0048630 skeletal muscle growth ( ); GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine ( ); GO:0019240 citrulline biosynthetic process ( ); GO:0004668 protein-arginine deiminase activity ( ); GO:0009374 biotin binding ( ); GO:0000052 citrulline metabolic process ( ); GO:0006107 oxaloacetate metabolic process ( ); GO:0016885 ligase activity, forming carbon-carbon bonds ( ); GO:0018195 peptidyl-arginine modification ( ); GO:0019794 nonprotein amino acid metabolic process ( ); GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines ( ); GO:0031406 carboxylic acid binding ( ); GO:0050879 multicellular organismal movement ( ); GO:0050881 musculoskeletal movement ( ); GO:0005892 nicotinic acetylcholine-gated receptor-channel complex ( ); GO:0004889 nicotinic acetylcholine-activated cation-selective channel activity ( ); GO:0042166 acetylcholine binding ( ); GO:0006094 gluconeogenesis ( ); GO:0043648 dicarboxylic acid metabolic process ( ); ----------------GO-------------- GO:0004736 pyruvate carboxylase activity ( 0.00040215151058165 ); GO:0004997 thyrotropin-releasing hormone receptor activity ( 0.00040215151058165 ); GO:0048630 skeletal muscle growth ( 0.00120603002276776 ); GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine ( 0.00200934280751575 ); GO:0019240 citrulline biosynthetic process ( 0.00200934280751575 ); GO:0004668 protein-arginine deiminase activity ( 0.00200934280751575 ); GO:0009374 biotin binding ( 0.00200934280751575 ); GO:0000052 citrulline metabolic process ( 0.00241078715875964 ); GO:0006107 oxaloacetate metabolic process ( 0.00281209020611339 ); GO:0016885 ligase activity, forming carbon-carbon bonds ( 0.00281209020611339 ); GO:0018195 peptidyl-arginine modification ( 0.00321325199221201 ); GO:0019794 nonprotein amino acid metabolic process ( 0.00401515195112445 ); GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines ( 0.0048164873763562 ); GO:0031406 carboxylic acid binding ( 0.0048164873763562 ); GO:0050879 multicellular organismal movement ( 0.00521694349531354 ); GO:0050881 musculoskeletal movement ( 0.00521694349531354 ); GO:0005892 nicotinic acetylcholine-gated receptor-channel complex ( 0.00521694349531354 ); GO:0004889 nicotinic acetylcholine-activated cation-selective channel activity ( 0.00601743275876021 ); GO:0042166 acetylcholine binding ( 0.00801619055166014 ); GO:0006094 gluconeogenesis ( 0.00881470841537757 ); GO:0043648 dicarboxylic acid metabolic process ( 0.00921375639145716 ); ----------------KEGG-------------- hsa00252 Alanine and aspartate metabolism ( 0.0112068884122597 ); hsa00020 Citrate cycle (TCA cycle) ( 0.0124010828643846 ); hsa00620 Pyruvate metabolism ( 0.016769005973377 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2585 ========================= ----------------C2-------------- REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION ( 0.00361427255967794 ); BIOCARTA_SRCRPTP_PATHWAY ( 0.00401515195112445 ); BIOCARTA_PTC1_PATHWAY ( 0.00401515195112445 ); REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES ( 0.00401515195112445 ); BIOCARTA_AKAP95_PATHWAY ( 0.00441589020915356 ); REACTOME_CYCLIN_A1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION ( 0.00561725860859519 ); REACTOME_PHOSPHORYLATION_OF_THE_APC ( 0.00641746598835713 ); REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B ( 0.00681735833992403 ); BIOCARTA_STATHMIN_PATHWAY ( 0.00721710985598756 ); BIOCARTA_CELLCYCLE_PATHWAY ( 0.00881470841537757 ); BIOCARTA_G2_PATHWAY ( 0.00921375639145716 ); ----------------C3-------------- ( 0.00721710985598756 ); ----------------C4-------------- module_83 ( 0.00589999096391577 ); module_439 ( 0.00801619055166014 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- ( 0.00878394218872406 ); ----------------GO-------------- ( 0.00846266329276749 ); ----------------KEGG-------------- hsa04115 p53 signaling pathway ( 0.0266332933873034 ); hsa03010 Ribosome ( 0.028595725634728 ); hsa04110 Cell cycle ( 0.0441709611824674 ); ----------------CARTA-------------- no2il12pathway ( 0.0048164873763562 ); stathminpathway ( 0.0048164873763562 ); hivnefpathway ( 0.0120031583447628 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.00340294947657301 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00396987243125361 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00493999687317193 ); TIAL1_iCLIP_(Wang_2010) ( 0.00582801082623543 ); TIA1_iCLIP_(Wang_2010) ( 0.00763566385523009 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0186711567637293 ); ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.0239577391041987 ); AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0319158813543042 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2622 ========================= ----------------C2-------------- REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA ( 0.00128303216734622 ); REACTOME_FURTHER_PLATELET_RELEASATE ( 0.00921375639145716 ); ----------------C3-------------- MGGAAGTG_V$GABP_B ( 0.0008472603119921 ); V$GABP_B ( 0.00174374366242167 ); V$YY1_Q6 ( 0.00183082538027867 ); V$ETS_Q4 ( 0.00210433993231834 ); V$ZF5_01 ( 0.00219958416718463 ); ----------------C4-------------- MORF_AP3D1 ( 0.000970469008840932 ); MORF_G22P1 ( 0.00149483987238232 ); MORF_ACP1 ( 0.00222371227489467 ); MORF_XRCC5 ( 0.00306225453876942 ); MORF_HDAC1 ( 0.00340961582101358 ); MORF_GNB1 ( 0.005190305832379 ); MORF_RAD23A ( 0.00665210797152454 ); ----------------C5-------------- ENVELOPE ( 0.00178702816025318 ); ORGANELLE_ENVELOPE ( 0.00178702816025318 ); U12_DEPENDENT_SPLICEOSOME ( 0.00281209020611339 ); RNA_BINDING ( 0.0038059366624902 ); ORGANELLE_MEMBRANE ( 0.00552115000148685 ); AEROBIC_RESPIRATION ( 0.00601743275876021 ); RNA_SPLICING_FACTOR_ACTIVITY__TRANSESTERIFICATION_MECHANISM ( 0.00641746598835713 ); ATP_DEPENDENT_RNA_HELICASE_ACTIVITY ( 0.00681735833992403 ); RNA_DEPENDENT_ATPASE_ACTIVITY ( 0.00721710985598756 ); RNA_EXPORT_FROM_NUCLEUS ( 0.0076167205790646 ); CELLULAR_RESPIRATION ( 0.0076167205790646 ); SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX ( 0.00801619055166014 ); INTRACELLULAR_ORGANELLE_PART ( 0.00853845187288038 ); ORGANELLE_PART ( 0.00864258529545872 ); MITOCHONDRIAL_RESPIRATORY_CHAIN ( 0.00921375639145716 ); ORGANELLE_OUTER_MEMBRANE ( 0.00961266378697145 ); RNA_HELICASE_ACTIVITY ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0008092 cytoskeletal protein binding ( 0.00252432741939815 ); GO:0000354 cis assembly of pre-catalytic spliceosome ( 0.00761629997621439 ); GO:0045292 nuclear mRNA cis splicing, via spliceosome ( 0.00252432741939815 ); GO:0005682 snRNP U5 ( 0.00761629997621439 ); GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c ( 0.00252432741939815 ); GO:0008121 ubiquinol-cytochrome-c reductase activity ( 0.00761629997621439 ); GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors ( 0.00252432741939815 ); GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor ( 0.00761629997621439 ); GO:0017110 nucleoside-diphosphatase activity ( 0.00252432741939815 ); GO:0005684 U2-dependent spliceosome ( 0.00761629997621439 ); GO:0005689 U12-dependent spliceosome ( 0.00252432741939815 ); GO:0003779 actin binding ( 0.00761629997621439 ); GO:0005640 nuclear outer membrane ( 0.00252432741939815 ); GO:0004004 ATP-dependent RNA helicase activity ( 0.00761629997621439 ); GO:0008186 RNA-dependent ATPase activity ( 0.00252432741939815 ); GO:0006406 mRNA export from nucleus ( 0.00761629997621439 ); GO:0005856 cytoskeleton ( 0.00252432741939815 ); GO:0030532 small nuclear ribonucleoprotein complex ( 0.00761629997621439 ); GO:0031202 RNA splicing factor activity, transesterification mechanism ( 0.00252432741939815 ); ----------------GO-------------- GO:0008092 cytoskeletal protein binding ( 0.000497159685742645 ); GO:0000354 cis assembly of pre-catalytic spliceosome ( 0.000804161503941581 ); GO:0045292 nuclear mRNA cis splicing, via spliceosome ( 0.00120603002276776 ); GO:0005682 snRNP U5 ( 0.00160775710973693 ); GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c ( 0.00200934280751575 ); GO:0008121 ubiquinol-cytochrome-c reductase activity ( 0.00241078715875964 ); GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors ( 0.00241078715875964 ); GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor ( 0.00241078715875964 ); GO:0017110 nucleoside-diphosphatase activity ( 0.00241078715875964 ); GO:0005684 U2-dependent spliceosome ( 0.00401515195112445 ); GO:0005689 U12-dependent spliceosome ( 0.00441589020915356 ); GO:0003779 actin binding ( 0.00563356359176319 ); GO:0005640 nuclear outer membrane ( 0.00681735833992403 ); GO:0004004 ATP-dependent RNA helicase activity ( 0.00681735833992403 ); GO:0008186 RNA-dependent ATPase activity ( 0.00721710985598756 ); GO:0006406 mRNA export from nucleus ( 0.00881470841537757 ); GO:0005856 cytoskeleton ( 0.00948141662894965 ); GO:0030532 small nuclear ribonucleoprotein complex ( 0.00961266378697145 ); GO:0031202 RNA splicing factor activity, transesterification mechanism ( 0.00961266378697145 ); ----------------KEGG-------------- hsa00790 Folate biosynthesis ( 0.0131965112222548 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0203301788791369 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0203301788791369 ); hsa00240 Pyrimidine metabolism ( 0.0360214317890752 ); hsa05012 Parkinson's disease ( 0.0445575256792341 ); hsa00190 Oxidative phosphorylation ( 0.0449439533736001 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0146468900881076 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2717 ========================= ----------------C2-------------- REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK ( 0.00401515195112445 ); BIOCARTA_LEPTIN_PATHWAY ( 0.00441589020915356 ); REACTOME_ERKS_ARE_INACTIVATED ( 0.0048164873763562 ); REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 ( 0.00561725860859519 ); BIOCARTA_NO2IL12_PATHWAY ( 0.00681735833992403 ); REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE ( 0.00681735833992403 ); REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK ( 0.00681735833992403 ); BIOCARTA_TH1TH2_PATHWAY ( 0.00721710985598756 ); REACTOME_ERK_MAPK_TARGETS ( 0.00841551981626976 ); BIOCARTA_IL12_PATHWAY ( 0.00881470841537757 ); REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION ( 0.00961266378697145 ); ----------------C3-------------- V$ER_Q6 ( 5.40163458430665e-05 ); V$E4BP4_01 ( 0.00165871540499915 ); TTAYRTAA_V$E4BP4_01 ( 0.0022968562395007 ); V$HLF_01 ( 0.00242129020600337 ); V$PAX2_02 ( 0.00257476885836422 ); V$ER_Q6_02 ( 0.00270612100091895 ); WTTGKCTG_UNKNOWN ( 0.00958707538499727 ); ----------------C4-------------- module_407 ( 0.00521694349531354 ); module_173 ( 0.00601743275876021 ); module_368 ( 0.00721710985598756 ); ----------------C5-------------- MONOCARBOXYLIC_ACID_TRANSPORT ( 0.00401515195112445 ); MONOSACCHARIDE_BINDING ( 0.00441589020915356 ); MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00441589020915356 ); ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT ( 0.00681735833992403 ); INTERLEUKIN_RECEPTOR_ACTIVITY ( 0.0076167205790646 ); INTERLEUKIN_BINDING ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0008330 protein tyrosine/threonine phosphatase activity ( ); GO:0030134 ER to Golgi transport vesicle ( ); GO:0004526 ribonuclease P activity ( ); GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity ( ); GO:0033549 MAP kinase phosphatase activity ( ); GO:0046320 regulation of fatty acid oxidation ( ); GO:0004549 tRNA-specific ribonuclease activity ( ); GO:0005537 mannose binding ( ); GO:0015718 monocarboxylic acid transport ( ); GO:0008028 monocarboxylic acid transmembrane transporter activity ( ); GO:0019217 regulation of fatty acid metabolic process ( ); GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters ( ); ----------------GO-------------- GO:0008330 protein tyrosine/threonine phosphatase activity ( 0.00160775710973693 ); GO:0030134 ER to Golgi transport vesicle ( 0.00321325199221201 ); GO:0004526 ribonuclease P activity ( 0.00401515195112445 ); GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity ( 0.00401515195112445 ); GO:0033549 MAP kinase phosphatase activity ( 0.00401515195112445 ); GO:0046320 regulation of fatty acid oxidation ( 0.0048164873763562 ); GO:0004549 tRNA-specific ribonuclease activity ( 0.0048164873763562 ); GO:0005537 mannose binding ( 0.00521694349531354 ); GO:0015718 monocarboxylic acid transport ( 0.00721710985598756 ); GO:0008028 monocarboxylic acid transmembrane transporter activity ( 0.00801619055166014 ); GO:0019217 regulation of fatty acid metabolic process ( 0.00881470841537757 ); GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters ( 0.00881470841537757 ); ----------------KEGG-------------- hsa04140 Regulation of autophagy ( 0.0127988671427596 ); hsa04150 mTOR signaling pathway ( 0.018748831152876 ); hsa04920 Adipocytokine signaling pathway ( 0.0262403909374875 ); ----------------CARTA-------------- epopathway ( 0.00241078715875964 ); il3pathway ( 0.00521694349531354 ); mhcpathway ( 0.00521694349531354 ); il2pathway ( 0.0076167205790646 ); keratinocytepathway ( 0.013594015145227 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2764 ========================= ----------------C2-------------- REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS ( 0.00401515195112445 ); BIOCARTA_FIBRINOLYSIS_PATHWAY ( 0.0048164873763562 ); BIOCARTA_EXTRINSIC_PATHWAY ( 0.00521694349531354 ); BIOCARTA_PLATELETAPP_PATHWAY ( 0.00561725860859519 ); REACTOME_COMMON_PATHWAY ( 0.00561725860859519 ); REACTOME_INTRINSIC_PATHWAY ( 0.00681735833992403 ); REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS ( 0.00681735833992403 ); BIOCARTA_AMI_PATHWAY ( 0.0076167205790646 ); BIOCARTA_SPPA_PATHWAY ( 0.00841551981626976 ); BIOCARTA_INTRINSIC_PATHWAY ( 0.00921375639145716 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- PROTEIN_IMPORT_INTO_NUCLEUS__TRANSLOCATION ( 0.00441589020915356 ); TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN ( 0.00521694349531354 ); FEEDING_BEHAVIOR ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0005927 muscle tendon junction ( 0.000480955253391048 ); GO:0030891 VCB complex ( 0.00309111381352753 ); GO:0034430 monolayer-surrounded lipid storage body outer lipid monolayer ( 0.00561725860859519 ); GO:0034646 organelle-enclosing lipid monolayer ( 0.00997008436002493 ); GO:0030354 melanin-concentrating hormone activity ( 0.000480955253391048 ); GO:0007262 STAT protein nuclear translocation ( 0.00309111381352753 ); GO:0000153 cytoplasmic ubiquitin ligase complex ( 0.00561725860859519 ); GO:0010714 positive regulation of collagen metabolic process ( 0.00997008436002493 ); GO:0032967 positive regulation of collagen biosynthetic process ( 0.000480955253391048 ); GO:0070053 thrombospondin receptor activity ( 0.00309111381352753 ); GO:0030194 positive regulation of blood coagulation ( 0.00561725860859519 ); GO:0032965 regulation of collagen biosynthetic process ( 0.00997008436002493 ); GO:0050820 positive regulation of coagulation ( 0.000480955253391048 ); GO:0012511 monolayer-surrounded lipid storage body ( 0.00309111381352753 ); GO:0010712 regulation of collagen metabolic process ( 0.00561725860859519 ); GO:0044253 positive regulation of multicellular organismal metabolic process ( 0.00997008436002493 ); GO:0005811 lipid particle ( 0.000480955253391048 ); GO:0032964 collagen biosynthetic process ( 0.00309111381352753 ); GO:0044246 regulation of multicellular organismal metabolic process ( 0.00561725860859519 ); GO:0051209 release of sequestered calcium ion into cytosol ( 0.00997008436002493 ); GO:0051282 regulation of sequestering of calcium ion ( 0.000480955253391048 ); GO:0051283 negative regulation of sequestering of calcium ion ( 0.00309111381352753 ); GO:0045214 sarcomere organization ( 0.00561725860859519 ); GO:0051208 sequestering of calcium ion ( 0.00997008436002493 ); GO:0004806 triacylglycerol lipase activity ( 0.000480955253391048 ); GO:0051238 sequestering of metal ion ( 0.00309111381352753 ); GO:0042730 fibrinolysis ( 0.00561725860859519 ); GO:0030239 myofibril assembly ( 0.00997008436002493 ); GO:0055002 striated muscle cell development ( 0.000480955253391048 ); GO:0055001 muscle cell development ( 0.00309111381352753 ); GO:0060402 calcium ion transport into cytosol ( 0.00561725860859519 ); GO:0060401 cytosolic calcium ion transport ( 0.00997008436002493 ); GO:0007275 multicellular organismal development ( 0.000480955253391048 ); GO:0030195 negative regulation of blood coagulation ( 0.00309111381352753 ); GO:0031032 actomyosin structure organization ( 0.00561725860859519 ); ----------------GO-------------- GO:0005927 muscle tendon junction ( 0.00040215151058165 ); GO:0030891 VCB complex ( 0.000804161503941581 ); GO:0034430 monolayer-surrounded lipid storage body outer lipid monolayer ( 0.000804161503941581 ); GO:0034646 organelle-enclosing lipid monolayer ( 0.000804161503941581 ); GO:0030354 melanin-concentrating hormone activity ( 0.000804161503941581 ); GO:0007262 STAT protein nuclear translocation ( 0.00120603002276776 ); GO:0000153 cytoplasmic ubiquitin ligase complex ( 0.00120603002276776 ); GO:0010714 positive regulation of collagen metabolic process ( 0.00160775710973693 ); GO:0032967 positive regulation of collagen biosynthetic process ( 0.00160775710973693 ); GO:0070053 thrombospondin receptor activity ( 0.00160775710973693 ); GO:0030194 positive regulation of blood coagulation ( 0.00200934280751575 ); GO:0032965 regulation of collagen biosynthetic process ( 0.00200934280751575 ); GO:0050820 positive regulation of coagulation ( 0.00200934280751575 ); GO:0012511 monolayer-surrounded lipid storage body ( 0.00200934280751575 ); GO:0010712 regulation of collagen metabolic process ( 0.00241078715875964 ); GO:0044253 positive regulation of multicellular organismal metabolic process ( 0.00281209020611339 ); GO:0005811 lipid particle ( 0.00281209020611339 ); GO:0032964 collagen biosynthetic process ( 0.00361427255967794 ); GO:0044246 regulation of multicellular organismal metabolic process ( 0.00361427255967794 ); GO:0051209 release of sequestered calcium ion into cytosol ( 0.00361427255967794 ); GO:0051282 regulation of sequestering of calcium ion ( 0.00361427255967794 ); GO:0051283 negative regulation of sequestering of calcium ion ( 0.00361427255967794 ); GO:0045214 sarcomere organization ( 0.0048164873763562 ); GO:0051208 sequestering of calcium ion ( 0.0048164873763562 ); GO:0004806 triacylglycerol lipase activity ( 0.00601743275876021 ); GO:0051238 sequestering of metal ion ( 0.00641746598835713 ); GO:0042730 fibrinolysis ( 0.00681735833992403 ); GO:0030239 myofibril assembly ( 0.00721710985598756 ); GO:0055002 striated muscle cell development ( 0.00721710985598756 ); GO:0055001 muscle cell development ( 0.00801619055166014 ); GO:0060402 calcium ion transport into cytosol ( 0.00841551981626976 ); GO:0060401 cytosolic calcium ion transport ( 0.00881470841537757 ); GO:0007275 multicellular organismal development ( 0.00889717319858865 ); GO:0030195 negative regulation of blood coagulation ( 0.00961266378697145 ); GO:0031032 actomyosin structure organization ( 0.00961266378697145 ); ----------------KEGG-------------- hsa00790 Folate biosynthesis ( 0.0131965112222548 ); hsa04610 Complement and coagulation cascades ( 0.0270260571143742 ); ----------------CARTA-------------- ( 0.00521694349531354 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2846 ========================= ----------------C2-------------- REACTOME_STEROID_HORMONE_BIOSYNTHESIS ( 0.00561725860859519 ); REACTOME_STEROID_HORMONES ( 0.00841551981626976 ); ----------------C3-------------- ( 0.00247194651149353 ); ----------------C4-------------- ( ); ----------------C5-------------- RIBONUCLEOPROTEIN_BINDING ( 0.00361427255967794 ); CENTROSOME_CYCLE ( 0.00441589020915356 ); CENTROSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00601743275876021 ); MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS ( 0.00641746598835713 ); ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT ( 0.00681735833992403 ); MICROTUBULE_ORGANIZING_CENTER_PART ( 0.0076167205790646 ); ----------------GOSLIM-------------- GO:0043024 ribosomal small subunit binding ( 0.00637010859225099 ); GO:0003924 GTPase activity ( 0.00637010859225099 ); GO:0005813 centrosome ( 0.00637010859225099 ); GO:0005815 microtubule organizing center ( 0.00637010859225099 ); GO:0000242 pericentriolar material ( 0.00637010859225099 ); GO:0007098 centrosome cycle ( 0.00637010859225099 ); GO:0005525 GTP binding ( 0.00637010859225099 ); GO:0043021 ribonucleoprotein binding ( 0.00637010859225099 ); GO:0032561 guanyl ribonucleotide binding ( 0.00637010859225099 ); GO:0019001 guanyl nucleotide binding ( 0.00637010859225099 ); GO:0031023 microtubule organizing center organization ( 0.00637010859225099 ); GO:0051297 centrosome organization ( 0.00637010859225099 ); ----------------GO-------------- GO:0043024 ribosomal small subunit binding ( 0.000804161503941581 ); GO:0003924 GTPase activity ( 0.00217558279927685 ); GO:0005813 centrosome ( 0.00244655538690318 ); GO:0005815 microtubule organizing center ( 0.00267959995436819 ); GO:0000242 pericentriolar material ( 0.00321325199221201 ); GO:0007098 centrosome cycle ( 0.00681735833992403 ); GO:0005525 GTP binding ( 0.00744613611869092 ); GO:0043021 ribonucleoprotein binding ( 0.0076167205790646 ); GO:0032561 guanyl ribonucleotide binding ( 0.00783673407616491 ); GO:0019001 guanyl nucleotide binding ( 0.00792478943565247 ); GO:0031023 microtubule organizing center organization ( 0.00921375639145716 ); GO:0051297 centrosome organization ( 0.00921375639145716 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2975 ========================= ----------------C2-------------- BIOCARTA_EGFR_SMRTE_PATHWAY ( 0.00441589020915356 ); BIOCARTA_VDR_PATHWAY ( 0.0048164873763562 ); BIOCARTA_CARM1_PATHWAY ( 0.00521694349531354 ); KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS ( 0.00601743275876021 ); BIOCARTA_RARRXR_PATHWAY ( 0.00601743275876021 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY ( 0.00561725860859519 ); VITAMIN_METABOLIC_PROCESS ( 0.00681735833992403 ); DNA_POLYMERASE_ACTIVITY ( 0.00721710985598756 ); DAMAGED_DNA_BINDING ( 0.00841551981626976 ); ----------------GOSLIM-------------- GO:0003985 acetyl-CoA C-acetyltransferase activity ( ); GO:0006290 pyrimidine dimer repair ( ); GO:0033119 negative regulation of RNA splicing ( ); GO:0016453 C-acetyltransferase activity ( ); GO:0010225 response to UV-C ( ); GO:0055012 ventricular cardiac muscle cell differentiation ( ); GO:0006282 regulation of DNA repair ( ); GO:0006301 postreplication repair ( ); GO:0003706 ligand-regulated transcription factor activity ( ); GO:0000731 DNA synthesis during DNA repair ( ); GO:0055007 cardiac muscle cell differentiation ( ); GO:0004886 retinoid-X receptor activity ( ); GO:0043484 regulation of RNA splicing ( ); GO:0048384 retinoic acid receptor signaling pathway ( ); GO:0014855 striated muscle cell proliferation ( ); GO:0060038 cardiac muscle cell proliferation ( ); GO:0016408 C-acyltransferase activity ( ); GO:0032526 response to retinoic acid ( ); GO:0035051 cardiac cell differentiation ( ); GO:0003708 retinoic acid receptor activity ( ); GO:0033189 response to vitamin A ( ); GO:0033273 response to vitamin ( ); GO:0055010 ventricular cardiac muscle morphogenesis ( ); GO:0004190 aspartic-type endopeptidase activity ( ); GO:0070001 aspartic-type peptidase activity ( ); GO:0055008 cardiac muscle tissue morphogenesis ( ); GO:0060415 muscle tissue morphogenesis ( ); ----------------GO-------------- GO:0003985 acetyl-CoA C-acetyltransferase activity ( 0.00120603002276776 ); GO:0006290 pyrimidine dimer repair ( 0.00160775710973693 ); GO:0033119 negative regulation of RNA splicing ( 0.00160775710973693 ); GO:0016453 C-acetyltransferase activity ( 0.00160775710973693 ); GO:0010225 response to UV-C ( 0.00200934280751575 ); GO:0055012 ventricular cardiac muscle cell differentiation ( 0.00281209020611339 ); GO:0006282 regulation of DNA repair ( 0.00321325199221201 ); GO:0006301 postreplication repair ( 0.00321325199221201 ); GO:0003706 ligand-regulated transcription factor activity ( 0.00321325199221201 ); GO:0000731 DNA synthesis during DNA repair ( 0.00361427255967794 ); GO:0055007 cardiac muscle cell differentiation ( 0.00361427255967794 ); GO:0004886 retinoid-X receptor activity ( 0.00401515195112445 ); GO:0043484 regulation of RNA splicing ( 0.00441589020915356 ); GO:0048384 retinoic acid receptor signaling pathway ( 0.00441589020915356 ); GO:0014855 striated muscle cell proliferation ( 0.0048164873763562 ); GO:0060038 cardiac muscle cell proliferation ( 0.0048164873763562 ); GO:0016408 C-acyltransferase activity ( 0.0048164873763562 ); GO:0032526 response to retinoic acid ( 0.00521694349531354 ); GO:0035051 cardiac cell differentiation ( 0.00521694349531354 ); GO:0003708 retinoic acid receptor activity ( 0.00521694349531354 ); GO:0033189 response to vitamin A ( 0.00561725860859519 ); GO:0033273 response to vitamin ( 0.00601743275876021 ); GO:0055010 ventricular cardiac muscle morphogenesis ( 0.0076167205790646 ); GO:0004190 aspartic-type endopeptidase activity ( 0.00801619055166014 ); GO:0070001 aspartic-type peptidase activity ( 0.00801619055166014 ); GO:0055008 cardiac muscle tissue morphogenesis ( 0.00921375639145716 ); GO:0060415 muscle tissue morphogenesis ( 0.00921375639145716 ); ----------------KEGG-------------- hsa00072 Synthesis and degradation of ketone bodies ( 0.00361427255967794 ); hsa00632 Benzoate degradation via CoA ligation ( 0.00561725860859519 ); hsa05216 Thyroid cancer ( 0.0116050935415175 ); hsa00640 Propanoate metabolism ( 0.0139913789540209 ); hsa00650 Butanoate metabolism ( 0.0151826301186295 ); hsa00620 Pyruvate metabolism ( 0.016769005973377 ); hsa00071 Fatty acid metabolism ( 0.0183531454151488 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0183531454151488 ); hsa00310 Lysine degradation ( 0.0199350511468974 ); hsa00380 Tryptophan metabolism ( 0.0199350511468974 ); hsa05223 Non-small cell lung cancer ( 0.0215147258688544 ); hsa04920 Adipocytokine signaling pathway ( 0.0262403909374875 ); hsa03320 PPAR signaling pathway ( 0.0270260571143742 ); hsa03010 Ribosome ( 0.028595725634728 ); hsa05222 Small cell lung cancer ( 0.0340721304228946 ); ----------------CARTA-------------- soddpathway ( 0.000804161503941581 ); p35alzheimerspathway ( 0.00441589020915356 ); nfkbpathway ( 0.00681735833992403 ); pgc1apathway ( 0.00961266378697145 ); raccycdpathway ( 0.0100114306443726 ); ghpathway ( 0.0124010828643846 ); nfatpathway ( 0.0147856863984033 ); p38mapkpathway ( 0.016769005973377 ); metpathway ( 0.0175613550768865 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0407311861764626 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0449807536141605 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3015 ========================= ----------------C2-------------- BIOCARTA_P27_PATHWAY ( 0.00521694349531354 ); REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS ( 0.00681735833992403 ); REACTOME_SIGNALING_BY_BMP ( 0.00921375639145716 ); ----------------C3-------------- V$E12_Q6 ( 4.56397999571543e-05 ); GGCCAGT,MIR-193A,MIR-193B ( 0.000462473899833438 ); V$AP2ALPHA_01 ( 0.00208084632172438 ); V$AP2GAMMA_01 ( 0.00210433993231834 ); V$LMO2COM_01 ( 0.00242129020600337 ); V$E47_01 ( 0.00265320413762381 ); CAGGTG_V$E12_Q6 ( 0.0035068511589574 ); ----------------C4-------------- module_190 ( 0.0048164873763562 ); module_470 ( 0.00561725860859519 ); module_474 ( 0.00641746598835713 ); module_362 ( 0.00801619055166014 ); module_4 ( 0.00841551981626976 ); module_233 ( 0.00881470841537757 ); module_82 ( 0.00961266378697145 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0018169 ribosomal S6-glutamic acid ligase activity ( 0.00271331221728396 ); GO:0004145 diamine N-acetyltransferase activity ( 0.00271331221728396 ); GO:0005615 extracellular space ( 0.00271331221728396 ); GO:0014912 negative regulation of smooth muscle cell migration ( 0.00271331221728396 ); GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway ( 0.00271331221728396 ); GO:0030008 TRAPP complex ( 0.00271331221728396 ); GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ( 0.00271331221728396 ); GO:0009968 negative regulation of signal transduction ( 0.00271331221728396 ); GO:0010648 negative regulation of cell communication ( 0.00271331221728396 ); GO:0016942 insulin-like growth factor binding protein complex ( 0.00271331221728396 ); GO:0005499 vitamin D binding ( 0.00271331221728396 ); GO:0031994 insulin-like growth factor I binding ( 0.00271331221728396 ); GO:0007389 pattern specification process ( 0.00271331221728396 ); GO:0042074 cell migration involved in gastrulation ( 0.00271331221728396 ); GO:0044421 extracellular region part ( 0.00271331221728396 ); GO:0014910 regulation of smooth muscle cell migration ( 0.00271331221728396 ); GO:0048662 negative regulation of smooth muscle cell proliferation ( 0.00271331221728396 ); GO:0009948 anterior/posterior axis specification ( 0.00271331221728396 ); GO:0014909 smooth muscle cell migration ( 0.00271331221728396 ); GO:0043567 regulation of insulin-like growth factor receptor signaling pathway ( 0.00271331221728396 ); GO:0014812 muscle cell migration ( 0.00271331221728396 ); GO:0016477 cell migration ( 0.00271331221728396 ); GO:0030514 negative regulation of BMP signaling pathway ( 0.00271331221728396 ); GO:0008285 negative regulation of cell proliferation ( 0.00271331221728396 ); GO:0048870 cell motility ( 0.00271331221728396 ); GO:0005801 cis-Golgi network ( 0.00271331221728396 ); GO:0048009 insulin-like growth factor receptor signaling pathway ( 0.00271331221728396 ); GO:0009798 axis specification ( 0.00271331221728396 ); GO:0017148 negative regulation of translation ( 0.00271331221728396 ); GO:0030510 regulation of BMP signaling pathway ( 0.00271331221728396 ); GO:0007167 enzyme linked receptor protein signaling pathway ( 0.00271331221728396 ); GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ( 0.00271331221728396 ); GO:0048660 regulation of smooth muscle cell proliferation ( 0.00271331221728396 ); GO:0005520 insulin-like growth factor binding ( 0.00271331221728396 ); GO:0051246 regulation of protein metabolic process ( 0.00271331221728396 ); ----------------GO-------------- GO:0018169 ribosomal S6-glutamic acid ligase activity ( 0.00040215151058165 ); GO:0004145 diamine N-acetyltransferase activity ( 0.000804161503941581 ); GO:0005615 extracellular space ( 0.000911715467695454 ); GO:0014912 negative regulation of smooth muscle cell migration ( 0.00120603002276776 ); GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway ( 0.00120603002276776 ); GO:0030008 TRAPP complex ( 0.00120603002276776 ); GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ( 0.00120603002276776 ); GO:0009968 negative regulation of signal transduction ( 0.00135823604679403 ); GO:0010648 negative regulation of cell communication ( 0.00149483987238232 ); GO:0016942 insulin-like growth factor binding protein complex ( 0.00160775710973693 ); GO:0005499 vitamin D binding ( 0.00160775710973693 ); GO:0031994 insulin-like growth factor I binding ( 0.00200934280751575 ); GO:0007389 pattern specification process ( 0.00222371227489467 ); GO:0042074 cell migration involved in gastrulation ( 0.00241078715875964 ); GO:0044421 extracellular region part ( 0.00297524329910855 ); GO:0014910 regulation of smooth muscle cell migration ( 0.00321325199221201 ); GO:0048662 negative regulation of smooth muscle cell proliferation ( 0.00321325199221201 ); GO:0009948 anterior/posterior axis specification ( 0.00361427255967794 ); GO:0014909 smooth muscle cell migration ( 0.00361427255967794 ); GO:0043567 regulation of insulin-like growth factor receptor signaling pathway ( 0.00361427255967794 ); GO:0014812 muscle cell migration ( 0.00401515195112445 ); GO:0016477 cell migration ( 0.004799035529206 ); GO:0030514 negative regulation of BMP signaling pathway ( 0.0048164873763562 ); GO:0008285 negative regulation of cell proliferation ( 0.00486910004233344 ); GO:0048870 cell motility ( 0.00537292180595671 ); GO:0005801 cis-Golgi network ( 0.00561725860859519 ); GO:0048009 insulin-like growth factor receptor signaling pathway ( 0.00601743275876021 ); GO:0009798 axis specification ( 0.00681735833992403 ); GO:0017148 negative regulation of translation ( 0.0076167205790646 ); GO:0030510 regulation of BMP signaling pathway ( 0.0076167205790646 ); GO:0007167 enzyme linked receptor protein signaling pathway ( 0.00837188471759895 ); GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ( 0.00841551981626976 ); GO:0048660 regulation of smooth muscle cell proliferation ( 0.00961266378697145 ); GO:0005520 insulin-like growth factor binding ( 0.00961266378697145 ); GO:0051246 regulation of protein metabolic process ( 0.00992713610661634 ); ----------------KEGG-------------- hsa00220 Urea cycle and metabolism of amino groups ( 0.0116050935415175 ); hsa04330 Notch signaling pathway ( 0.0179573200705576 ); ----------------CARTA-------------- ( 0.00601743275876021 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0407311861764626 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0449807536141605 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3021 ========================= ----------------C2-------------- ( 0.00561725860859519 ); ----------------C3-------------- V$POU3F2_01 ( 0.000462473899833438 ); RAAGNYNNCTTY_UNKNOWN ( 0.0007857636026286 ); V$AP4_Q6 ( 0.00189748115953865 ); V$RP58_01 ( 0.00205747985013858 ); V$CDPCR3HD_01 ( 0.0021517082509511 ); V$TAL1BETAE47_01 ( 0.00222371227489467 ); V$CHX10_01 ( 0.00222371227489467 ); V$POU1F1_Q6 ( 0.00222371227489467 ); V$GATA3_01 ( 0.00224796704265788 ); V$TAL1BETAITF2_01 ( 0.00239615104826742 ); V$CDC5_01 ( 0.0027595384667992 ); V$NFAT_Q4_01 ( 0.00278643472788476 ); TTCYNRGAA_V$STAT5B_01 ( 0.00406009920126417 ); AAAYRNCTG_UNKNOWN ( 0.00555850299777959 ); TATAAA_V$TATA_01 ( 0.00581316347467462 ); ----------------C4-------------- ( ); ----------------C5-------------- SMOOTH_MUSCLE_CONTRACTION_GO_0006939 ( 0.0048164873763562 ); REGULATION_OF_MUSCLE_CONTRACTION ( 0.0076167205790646 ); ----------------GOSLIM-------------- GO:0048511 rhythmic process ( 0.00415337693562182 ); GO:0051239 regulation of multicellular organismal process ( 0.0051045836664562 ); GO:0021533 cell differentiation in hindbrain ( 0.00917485109532006 ); GO:0045987 positive regulation of smooth muscle contraction ( 0.00415337693562182 ); GO:0002021 response to dietary excess ( 0.0051045836664562 ); GO:0045933 positive regulation of muscle contraction ( 0.00917485109532006 ); GO:0051591 response to cAMP ( 0.00415337693562182 ); GO:0009409 response to cold ( 0.0051045836664562 ); GO:0045666 positive regulation of neuron differentiation ( 0.00917485109532006 ); GO:0019953 sexual reproduction ( 0.00415337693562182 ); GO:0001541 ovarian follicle development ( 0.0051045836664562 ); GO:0032868 response to insulin stimulus ( 0.00917485109532006 ); GO:0005184 neuropeptide hormone activity ( 0.00415337693562182 ); GO:0048878 chemical homeostasis ( 0.0051045836664562 ); GO:0006940 regulation of smooth muscle contraction ( 0.00917485109532006 ); GO:0045665 negative regulation of neuron differentiation ( 0.00415337693562182 ); ----------------GO-------------- GO:0048511 rhythmic process ( 0.000407877559046298 ); GO:0051239 regulation of multicellular organismal process ( 0.00132594039384822 ); GO:0021533 cell differentiation in hindbrain ( 0.00321325199221201 ); GO:0045987 positive regulation of smooth muscle contraction ( 0.00321325199221201 ); GO:0002021 response to dietary excess ( 0.00361427255967794 ); GO:0045933 positive regulation of muscle contraction ( 0.00361427255967794 ); GO:0051591 response to cAMP ( 0.00441589020915356 ); GO:0009409 response to cold ( 0.00521694349531354 ); GO:0045666 positive regulation of neuron differentiation ( 0.00601743275876021 ); GO:0019953 sexual reproduction ( 0.00714875613343667 ); GO:0001541 ovarian follicle development ( 0.00721710985598756 ); GO:0032868 response to insulin stimulus ( 0.0076167205790646 ); GO:0005184 neuropeptide hormone activity ( 0.0076167205790646 ); GO:0048878 chemical homeostasis ( 0.00837188471759895 ); GO:0006940 regulation of smooth muscle contraction ( 0.00841551981626976 ); GO:0045665 negative regulation of neuron differentiation ( 0.00961266378697145 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.00721710985598756 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0124037234915922 ); ----------------ARE-------------- ( ); ============================ group3062 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( ); ----------------GO-------------- GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( 0.00841551981626976 ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( 0.00841551981626976 ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( 0.00841551981626976 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3096 ========================= ----------------C2-------------- REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION ( 0.00401515195112445 ); REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING ( 0.0048164873763562 ); REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS ( 0.00641746598835713 ); REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL ( 0.00681735833992403 ); REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS ( 0.00841551981626976 ); REACTOME_EGFR_DOWNREGULATION ( 0.00961266378697145 ); ----------------C3-------------- V$ELK1_02 ( 0.0019199554182128 ); V$MEF2_04 ( 0.00841551981626976 ); ----------------C4-------------- MORF_GPX4 ( 0.000164858096578013 ); MORF_PPP1CA ( 0.00147493646966026 ); MORF_SKP1A ( 0.00210433993231834 ); MORF_RAC1 ( 0.00257476885836422 ); MORF_AP2M1 ( 0.00262693362988407 ); module_39 ( 0.00401515195112445 ); MORF_RAN ( 0.00402790267061662 ); module_264 ( 0.00441589020915356 ); MORF_CSNK2B ( 0.00445591561468543 ); module_395 ( 0.00561725860859519 ); module_509 ( 0.00561725860859519 ); module_151 ( 0.00589999096391577 ); module_114 ( 0.00657095510264563 ); module_73 ( 0.00841551981626976 ); ----------------C5-------------- CARBOHYDRATE_METABOLIC_PROCESS ( 0.00203424059749427 ); HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX ( 0.00361427255967794 ); NUCLEOTIDE_SUGAR_METABOLIC_PROCESS ( 0.00361427255967794 ); ENDOCYTIC_VESICLE ( 0.00561725860859519 ); VESICLE_COAT ( 0.00601743275876021 ); COATED_VESICLE_MEMBRANE ( 0.00601743275876021 ); REGULATION_OF_ENDOCYTOSIS ( 0.00601743275876021 ); MEMBRANE_COAT ( 0.00641746598835713 ); COATED_MEMBRANE ( 0.00641746598835713 ); INTERLEUKIN_RECEPTOR_ACTIVITY ( 0.0076167205790646 ); INTERLEUKIN_BINDING ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity ( ); GO:0050577 GDP-L-fucose synthase activity ( ); GO:0006005 L-fucose biosynthetic process ( ); GO:0042350 GDP-L-fucose biosynthetic process ( ); GO:0042351 'de novo' GDP-L-fucose biosynthetic process ( ); GO:0042353 fucose biosynthetic process ( ); GO:0046368 GDP-L-fucose metabolic process ( ); GO:0016853 isomerase activity ( ); GO:0009226 nucleotide-sugar biosynthetic process ( ); GO:0004165 dodecenoyl-CoA delta-isomerase activity ( ); GO:0030122 AP-2 adaptor complex ( ); GO:0030128 clathrin coat of endocytic vesicle ( ); GO:0048268 clathrin coat assembly ( ); GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity ( ); GO:0030669 clathrin-coated endocytic vesicle membrane ( ); GO:0050690 regulation of defense response to virus by virus ( ); GO:0030132 clathrin coat of coated pit ( ); GO:0030666 endocytic vesicle membrane ( ); GO:0045334 clathrin-coated endocytic vesicle ( ); GO:0009225 nucleotide-sugar metabolic process ( ); GO:0042354 L-fucose metabolic process ( ); GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds ( ); GO:0050688 regulation of defense response to virus ( ); GO:0006901 vesicle coating ( ); GO:0030125 clathrin vesicle coat ( ); GO:0006900 membrane budding ( ); GO:0016254 preassembly of GPI anchor in ER membrane ( ); GO:0030530 heterogeneous nuclear ribonucleoprotein complex ( ); GO:0006004 fucose metabolic process ( ); GO:0006635 fatty acid beta-oxidation ( ); GO:0043900 regulation of multi-organism process ( ); GO:0007159 leukocyte adhesion ( ); GO:0002831 regulation of response to biotic stimulus ( ); GO:0019835 cytolysis ( ); ----------------GO-------------- GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity ( 0.00040215151058165 ); GO:0050577 GDP-L-fucose synthase activity ( 0.00040215151058165 ); GO:0006005 L-fucose biosynthetic process ( 0.000804161503941581 ); GO:0042350 GDP-L-fucose biosynthetic process ( 0.000804161503941581 ); GO:0042351 'de novo' GDP-L-fucose biosynthetic process ( 0.000804161503941581 ); GO:0042353 fucose biosynthetic process ( 0.000804161503941581 ); GO:0046368 GDP-L-fucose metabolic process ( 0.000804161503941581 ); GO:0016853 isomerase activity ( 0.00101961329241731 ); GO:0009226 nucleotide-sugar biosynthetic process ( 0.00120603002276776 ); GO:0004165 dodecenoyl-CoA delta-isomerase activity ( 0.00120603002276776 ); GO:0030122 AP-2 adaptor complex ( 0.00160775710973693 ); GO:0030128 clathrin coat of endocytic vesicle ( 0.00160775710973693 ); GO:0048268 clathrin coat assembly ( 0.00200934280751575 ); GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity ( 0.00200934280751575 ); GO:0030669 clathrin-coated endocytic vesicle membrane ( 0.00241078715875964 ); GO:0050690 regulation of defense response to virus by virus ( 0.00321325199221201 ); GO:0030132 clathrin coat of coated pit ( 0.00361427255967794 ); GO:0030666 endocytic vesicle membrane ( 0.00361427255967794 ); GO:0045334 clathrin-coated endocytic vesicle ( 0.00361427255967794 ); GO:0009225 nucleotide-sugar metabolic process ( 0.00441589020915356 ); GO:0042354 L-fucose metabolic process ( 0.00441589020915356 ); GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds ( 0.00441589020915356 ); GO:0050688 regulation of defense response to virus ( 0.00561725860859519 ); GO:0006901 vesicle coating ( 0.00601743275876021 ); GO:0030125 clathrin vesicle coat ( 0.00601743275876021 ); GO:0006900 membrane budding ( 0.00641746598835713 ); GO:0016254 preassembly of GPI anchor in ER membrane ( 0.00641746598835713 ); GO:0030530 heterogeneous nuclear ribonucleoprotein complex ( 0.00641746598835713 ); GO:0006004 fucose metabolic process ( 0.00681735833992403 ); GO:0006635 fatty acid beta-oxidation ( 0.0076167205790646 ); GO:0043900 regulation of multi-organism process ( 0.00841551981626976 ); GO:0007159 leukocyte adhesion ( 0.00881470841537757 ); GO:0002831 regulation of response to biotic stimulus ( 0.00921375639145716 ); GO:0019835 cytolysis ( 0.00961266378697145 ); ----------------KEGG-------------- hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis ( 0.00921375639145716 ); hsa00051 Fructose and mannose metabolism ( 0.0139913789540209 ); hsa00071 Fatty acid metabolism ( 0.0183531454151488 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0250608508315672 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00493999687317193 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0449807536141605 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3102 ========================= ----------------C2-------------- REACTOME_MITOTIC_M_M_G1_PHASES ( 0.00167977967602891 ); REACTOME_CELL_CYCLE_MITOTIC ( 0.0060938239245456 ); BIOCARTA_PROTEASOME_PATHWAY ( 0.0076167205790646 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_DEK ( 0.0035595926811061 ); MORF_RAN ( 0.00402790267061662 ); MORF_SOD1 ( 0.00412485681014262 ); module_50 ( 0.00521694349531354 ); ----------------C5-------------- CELL_SOMA ( 0.00401515195112445 ); DENDRITE ( 0.00641746598835713 ); ----------------GOSLIM-------------- GO:0042791 5S class rRNA transcription ( ); GO:0042797 tRNA transcription from RNA polymerase III promoter ( ); GO:0000127 transcription factor TFIIIC complex ( ); GO:0009304 tRNA transcription ( ); GO:0006656 phosphatidylcholine biosynthetic process ( ); GO:0003709 RNA polymerase III transcription factor activity ( ); GO:0009303 rRNA transcription ( ); GO:0046470 phosphatidylcholine metabolic process ( ); GO:0005839 proteasome core complex ( ); GO:0004298 threonine-type endopeptidase activity ( ); GO:0070003 threonine-type peptidase activity ( ); ----------------GO-------------- GO:0042791 5S class rRNA transcription ( 0.00241078715875964 ); GO:0042797 tRNA transcription from RNA polymerase III promoter ( 0.00241078715875964 ); GO:0000127 transcription factor TFIIIC complex ( 0.00241078715875964 ); GO:0009304 tRNA transcription ( 0.00281209020611339 ); GO:0006656 phosphatidylcholine biosynthetic process ( 0.00401515195112445 ); GO:0003709 RNA polymerase III transcription factor activity ( 0.00401515195112445 ); GO:0009303 rRNA transcription ( 0.00561725860859519 ); GO:0046470 phosphatidylcholine metabolic process ( 0.00601743275876021 ); GO:0005839 proteasome core complex ( 0.0076167205790646 ); GO:0004298 threonine-type endopeptidase activity ( 0.00801619055166014 ); GO:0070003 threonine-type peptidase activity ( 0.00801619055166014 ); ----------------KEGG-------------- hsa03050 Proteasome ( 0.0175613550768865 ); hsa03320 PPAR signaling pathway ( 0.0270260571143742 ); ----------------CARTA-------------- nkcellspathway ( 0.00881470841537757 ); no1pathway ( 0.015579433893953 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3119 ========================= ----------------C2-------------- BIOCARTA_IL6_PATHWAY ( 0.00881470841537757 ); BIOCARTA_HER2_PATHWAY ( 0.00881470841537757 ); ----------------C3-------------- ( 0.00521694349531354 ); ----------------C4-------------- ( 0.00841551981626976 ); ----------------C5-------------- MULTICELLULAR_ORGANISMAL_DEVELOPMENT ( 0.00638680883520556 ); INTERLEUKIN_RECEPTOR_ACTIVITY ( 0.0076167205790646 ); INTERLEUKIN_BINDING ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0002384 hepatic immune response ( ); GO:0004915 interleukin-6 receptor activity ( ); GO:0019981 interleukin-6 binding ( ); GO:0002548 monocyte chemotaxis ( ); GO:0005896 interleukin-6 receptor complex ( ); GO:0004897 ciliary neurotrophic factor receptor activity ( ); GO:0002251 organ or tissue specific immune response ( ); GO:0032722 positive regulation of chemokine production ( ); GO:0002688 regulation of leukocyte chemotaxis ( ); GO:0002690 positive regulation of leukocyte chemotaxis ( ); GO:0032755 positive regulation of interleukin-6 production ( ); GO:0050829 defense response to Gram-negative bacterium ( ); GO:0002687 positive regulation of leukocyte migration ( ); GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0002685 regulation of leukocyte migration ( ); GO:0032642 regulation of chemokine production ( ); GO:0032602 chemokine production ( ); GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein ( ); GO:0031018 endocrine pancreas development ( ); GO:0042503 tyrosine phosphorylation of Stat3 protein ( ); GO:0045768 positive regulation of anti-apoptosis ( ); GO:0048661 positive regulation of smooth muscle cell proliferation ( ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( ); GO:0040017 positive regulation of locomotion ( ); GO:0045669 positive regulation of osteoblast differentiation ( ); GO:0045767 regulation of anti-apoptosis ( ); GO:0050920 regulation of chemotaxis ( ); GO:0050921 positive regulation of chemotaxis ( ); GO:0046427 positive regulation of JAK-STAT cascade ( ); GO:0032675 regulation of interleukin-6 production ( ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( ); GO:0048520 positive regulation of behavior ( ); GO:0031016 pancreas development ( ); GO:0034097 response to cytokine stimulus ( ); GO:0050795 regulation of behavior ( ); GO:0048660 regulation of smooth muscle cell proliferation ( ); GO:0031901 early endosome membrane ( ); ----------------GO-------------- GO:0002384 hepatic immune response ( 0.000804161503941581 ); GO:0004915 interleukin-6 receptor activity ( 0.000804161503941581 ); GO:0019981 interleukin-6 binding ( 0.000804161503941581 ); GO:0002548 monocyte chemotaxis ( 0.00120603002276776 ); GO:0005896 interleukin-6 receptor complex ( 0.00120603002276776 ); GO:0004897 ciliary neurotrophic factor receptor activity ( 0.00160775710973693 ); GO:0002251 organ or tissue specific immune response ( 0.00200934280751575 ); GO:0032722 positive regulation of chemokine production ( 0.00200934280751575 ); GO:0002688 regulation of leukocyte chemotaxis ( 0.00281209020611339 ); GO:0002690 positive regulation of leukocyte chemotaxis ( 0.00281209020611339 ); GO:0032755 positive regulation of interleukin-6 production ( 0.00281209020611339 ); GO:0050829 defense response to Gram-negative bacterium ( 0.00361427255967794 ); GO:0002687 positive regulation of leukocyte migration ( 0.00401515195112445 ); GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ( 0.00401515195112445 ); GO:0002685 regulation of leukocyte migration ( 0.00441589020915356 ); GO:0032642 regulation of chemokine production ( 0.0048164873763562 ); GO:0032602 chemokine production ( 0.00521694349531354 ); GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein ( 0.00561725860859519 ); GO:0031018 endocrine pancreas development ( 0.00601743275876021 ); GO:0042503 tyrosine phosphorylation of Stat3 protein ( 0.00601743275876021 ); GO:0045768 positive regulation of anti-apoptosis ( 0.00641746598835713 ); GO:0048661 positive regulation of smooth muscle cell proliferation ( 0.00641746598835713 ); GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ( 0.00721710985598756 ); GO:0040017 positive regulation of locomotion ( 0.0076167205790646 ); GO:0045669 positive regulation of osteoblast differentiation ( 0.0076167205790646 ); GO:0045767 regulation of anti-apoptosis ( 0.0076167205790646 ); GO:0050920 regulation of chemotaxis ( 0.0076167205790646 ); GO:0050921 positive regulation of chemotaxis ( 0.0076167205790646 ); GO:0046427 positive regulation of JAK-STAT cascade ( 0.00801619055166014 ); GO:0032675 regulation of interleukin-6 production ( 0.00881470841537757 ); GO:0042509 regulation of tyrosine phosphorylation of STAT protein ( 0.00881470841537757 ); GO:0048520 positive regulation of behavior ( 0.00881470841537757 ); GO:0031016 pancreas development ( 0.00921375639145716 ); GO:0034097 response to cytokine stimulus ( 0.00921375639145716 ); GO:0050795 regulation of behavior ( 0.00921375639145716 ); GO:0048660 regulation of smooth muscle cell proliferation ( 0.00961266378697145 ); GO:0031901 early endosome membrane ( 0.00961266378697145 ); ----------------KEGG-------------- hsa03420 Nucleotide excision repair ( 0.0171652503919058 ); hsa04640 Hematopoietic cell lineage ( 0.0332914446808504 ); ----------------CARTA-------------- insulinpathway ( 0.00441589020915356 ); igf1pathway ( 0.00921375639145716 ); il1rpathway ( 0.0108085429145913 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3134 ========================= ----------------C2-------------- BIOCARTA_ERYTH_PATHWAY ( 0.00601743275876021 ); BIOCARTA_IL17_PATHWAY ( 0.00641746598835713 ); BIOCARTA_MCM_PATHWAY ( 0.00721710985598756 ); REACTOME_OLFACTORY_SIGNALING_PATHWAY ( 0.00761859181464929 ); KEGG_OLFACTORY_TRANSDUCTION ( 0.0096353225724933 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0045636 positive regulation of melanocyte differentiation ( ); GO:0050942 positive regulation of pigment cell differentiation ( ); GO:0048087 positive regulation of pigmentation during development ( ); GO:0045634 regulation of melanocyte differentiation ( ); GO:0050932 regulation of pigment cell differentiation ( ); GO:0048070 regulation of pigmentation during development ( ); GO:0030318 melanocyte differentiation ( ); GO:0046579 positive regulation of Ras protein signal transduction ( ); GO:0001755 neural crest cell migration ( ); GO:0050931 pigment cell differentiation ( ); GO:0051057 positive regulation of small GTPase mediated signal transduction ( ); GO:0045740 positive regulation of DNA replication ( ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( ); GO:0014032 neural crest cell development ( ); GO:0014033 neural crest cell differentiation ( ); GO:0004984 olfactory receptor activity ( ); GO:0007608 sensory perception of smell ( ); GO:0048066 pigmentation during development ( ); ----------------GO-------------- GO:0045636 positive regulation of melanocyte differentiation ( 0.00120603002276776 ); GO:0050942 positive regulation of pigment cell differentiation ( 0.00120603002276776 ); GO:0048087 positive regulation of pigmentation during development ( 0.00160775710973693 ); GO:0045634 regulation of melanocyte differentiation ( 0.00200934280751575 ); GO:0050932 regulation of pigment cell differentiation ( 0.00200934280751575 ); GO:0048070 regulation of pigmentation during development ( 0.00361427255967794 ); GO:0030318 melanocyte differentiation ( 0.00521694349531354 ); GO:0046579 positive regulation of Ras protein signal transduction ( 0.00521694349531354 ); GO:0001755 neural crest cell migration ( 0.00561725860859519 ); GO:0050931 pigment cell differentiation ( 0.00561725860859519 ); GO:0051057 positive regulation of small GTPase mediated signal transduction ( 0.00561725860859519 ); GO:0045740 positive regulation of DNA replication ( 0.0076167205790646 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.00841551981626976 ); GO:0014032 neural crest cell development ( 0.00841551981626976 ); GO:0014033 neural crest cell differentiation ( 0.00841551981626976 ); GO:0004984 olfactory receptor activity ( 0.00846266329276749 ); GO:0007608 sensory perception of smell ( 0.00920510613918962 ); GO:0048066 pigmentation during development ( 0.00961266378697145 ); ----------------KEGG-------------- hsa04740 Olfactory transduction ( 0.00929992937507883 ); hsa04640 Hematopoietic cell lineage ( 0.0332914446808504 ); hsa04916 Melanogenesis ( 0.0402977829454378 ); ----------------CARTA-------------- longevitypathway ( 0.0108085429145913 ); mapkpathway ( 0.0179573200705576 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3142 ========================= ----------------C2-------------- REACTOME_METABOLISM_OF_PROTEINS ( 0.00309052050387063 ); REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION ( 0.00441589020915356 ); REACTOME_GLUTATHIONE_CONJUGATION ( 0.00681735833992403 ); ----------------C3-------------- ( ); ----------------C4-------------- module_101 ( 0.00401515195112445 ); module_132 ( 0.00521694349531354 ); module_310 ( 0.00841551981626976 ); ----------------C5-------------- ANTI_APOPTOSIS ( 0.000860411026681424 ); NEGATIVE_REGULATION_OF_APOPTOSIS ( 0.00139661755474805 ); NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH ( 0.00141600291742381 ); NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS ( 0.00242129020600337 ); FEMALE_GAMETE_GENERATION ( 0.00681735833992403 ); REGULATION_OF_APOPTOSIS ( 0.0071908940175956 ); REGULATION_OF_PROGRAMMED_CELL_DEATH ( 0.00723314701739872 ); ----------------GOSLIM-------------- GO:0000054 ribosome export from nucleus ( 0.0047043122904375 ); GO:0000056 ribosomal small subunit export from nucleus ( 0.0047043122904375 ); GO:0033750 ribosome localization ( 0.0047043122904375 ); GO:0033753 establishment of ribosome localization ( 0.0047043122904375 ); GO:0044445 cytosolic part ( 0.0047043122904375 ); GO:0006916 anti-apoptosis ( 0.0047043122904375 ); GO:0042274 ribosomal small subunit biogenesis ( 0.0047043122904375 ); GO:0016272 prefoldin complex ( 0.0047043122904375 ); GO:0005829 cytosol ( 0.0047043122904375 ); GO:0043066 negative regulation of apoptosis ( 0.0047043122904375 ); GO:0043069 negative regulation of programmed cell death ( 0.0047043122904375 ); GO:0004364 glutathione transferase activity ( 0.0047043122904375 ); ----------------GO-------------- GO:0000054 ribosome export from nucleus ( 0.00040215151058165 ); GO:0000056 ribosomal small subunit export from nucleus ( 0.00040215151058165 ); GO:0033750 ribosome localization ( 0.00040215151058165 ); GO:0033753 establishment of ribosome localization ( 0.00040215151058165 ); GO:0044445 cytosolic part ( 0.00113887911531526 ); GO:0006916 anti-apoptosis ( 0.00210433993231834 ); GO:0042274 ribosomal small subunit biogenesis ( 0.00361427255967794 ); GO:0016272 prefoldin complex ( 0.00401515195112445 ); GO:0005829 cytosol ( 0.00448010374764657 ); GO:0043066 negative regulation of apoptosis ( 0.00462597276813825 ); GO:0043069 negative regulation of programmed cell death ( 0.004799035529206 ); GO:0004364 glutathione transferase activity ( 0.00881470841537757 ); ----------------KEGG-------------- hsa00480 Glutathione metabolism ( 0.0199350511468974 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0246673930707164 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0254541697016302 ); hsa03010 Ribosome ( 0.028595725634728 ); hsa05215 Prostate cancer ( 0.0348522644575099 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO2_PAR-CLIP_(Kishore_2011) ( 0.00396987243125361 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00493999687317193 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0186711567637293 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0407311861764626 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3157 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00401515195112445 ); HISTONE_METHYLTRANSFERASE_ACTIVITY ( 0.00441589020915356 ); N_METHYLTRANSFERASE_ACTIVITY ( 0.00521694349531354 ); PROTEIN_METHYLTRANSFERASE_ACTIVITY ( 0.00561725860859519 ); ACTIVATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR ( 0.00721710985598756 ); RECEPTOR_BINDING ( 0.00878394218872406 ); CHROMATIN_REMODELING ( 0.00921375639145716 ); S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY ( 0.00921375639145716 ); POSITIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0031856 parathyroid hormone receptor binding ( ); GO:0046974 histone methyltransferase activity (H3-K9 specific) ( ); GO:0008628 induction of apoptosis by hormones ( ); GO:0035081 induction of programmed cell death by hormones ( ); GO:0030816 positive regulation of cAMP metabolic process ( ); GO:0030819 positive regulation of cAMP biosynthetic process ( ); GO:0030801 positive regulation of cyclic nucleotide metabolic process ( ); GO:0030804 positive regulation of cyclic nucleotide biosynthetic process ( ); GO:0030810 positive regulation of nucleotide biosynthetic process ( ); GO:0045981 positive regulation of nucleotide metabolic process ( ); GO:0007186 G-protein coupled receptor protein signaling pathway ( ); GO:0045453 bone resorption ( ); GO:0005164 tumor necrosis factor receptor binding ( ); GO:0032813 tumor necrosis factor receptor superfamily binding ( ); GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( ); ----------------GO-------------- GO:0031856 parathyroid hormone receptor binding ( 0.00040215151058165 ); GO:0046974 histone methyltransferase activity (H3-K9 specific) ( 0.000804161503941581 ); GO:0008628 induction of apoptosis by hormones ( 0.00120603002276776 ); GO:0035081 induction of programmed cell death by hormones ( 0.00120603002276776 ); GO:0030816 positive regulation of cAMP metabolic process ( 0.00200934280751575 ); GO:0030819 positive regulation of cAMP biosynthetic process ( 0.00200934280751575 ); GO:0030801 positive regulation of cyclic nucleotide metabolic process ( 0.00281209020611339 ); GO:0030804 positive regulation of cyclic nucleotide biosynthetic process ( 0.00281209020611339 ); GO:0030810 positive regulation of nucleotide biosynthetic process ( 0.00281209020611339 ); GO:0045981 positive regulation of nucleotide metabolic process ( 0.00281209020611339 ); GO:0007186 G-protein coupled receptor protein signaling pathway ( 0.0056186166568174 ); GO:0045453 bone resorption ( 0.00681735833992403 ); GO:0005164 tumor necrosis factor receptor binding ( 0.00721710985598756 ); GO:0032813 tumor necrosis factor receptor superfamily binding ( 0.0076167205790646 ); GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( 0.00841551981626976 ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( 0.00841551981626976 ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( 0.00841551981626976 ); ----------------KEGG-------------- ( 0.0199350511468974 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3172 ========================= ----------------C2-------------- REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS ( 0.00401515195112445 ); BIOCARTA_CDK5_PATHWAY ( 0.00441589020915356 ); BIOCARTA_BARR_MAPK_PATHWAY ( 0.0048164873763562 ); REACTOME_SHC_MEDIATED_SIGNALLING ( 0.0048164873763562 ); REACTOME_ERKS_ARE_INACTIVATED ( 0.0048164873763562 ); BIOCARTA_ARENRF2_PATHWAY ( 0.00521694349531354 ); REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING ( 0.00521694349531354 ); REACTOME_SHC_RELATED_EVENTS ( 0.00521694349531354 ); REACTOME_SOS_MEDIATED_SIGNALLING ( 0.00521694349531354 ); REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN ( 0.00561725860859519 ); BIOCARTA_BARRESTIN_SRC_PATHWAY ( 0.00601743275876021 ); BIOCARTA_CDMAC_PATHWAY ( 0.00641746598835713 ); REACTOME_FRS2_MEDIATED_ACTIVATION ( 0.00641746598835713 ); BIOCARTA_HCMV_PATHWAY ( 0.00681735833992403 ); BIOCARTA_ERK5_PATHWAY ( 0.00681735833992403 ); BIOCARTA_PTEN_PATHWAY ( 0.00721710985598756 ); BIOCARTA_SPRY_PATHWAY ( 0.00721710985598756 ); BIOCARTA_MAL_PATHWAY ( 0.0076167205790646 ); BIOCARTA_ATRBRCA_PATHWAY ( 0.00801619055166014 ); BIOCARTA_SPPA_PATHWAY ( 0.00841551981626976 ); BIOCARTA_TFF_PATHWAY ( 0.00841551981626976 ); REACTOME_ERK_MAPK_TARGETS ( 0.00841551981626976 ); BIOCARTA_CERAMIDE_PATHWAY ( 0.00881470841537757 ); BIOCARTA_HER2_PATHWAY ( 0.00881470841537757 ); BIOCARTA_CCR3_PATHWAY ( 0.00921375639145716 ); BIOCARTA_ECM_PATHWAY ( 0.00921375639145716 ); BIOCARTA_IGF1R_PATHWAY ( 0.00921375639145716 ); KEGG_DORSO_VENTRAL_AXIS_FORMATION ( 0.00961266378697145 ); BIOCARTA_CXCR4_PATHWAY ( 0.00961266378697145 ); BIOCARTA_MCALPAIN_PATHWAY ( 0.00961266378697145 ); BIOCARTA_EIF4_PATHWAY ( 0.00961266378697145 ); REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION ( 0.00961266378697145 ); ----------------C3-------------- ( 0.00721710985598756 ); ----------------C4-------------- ( ); ----------------C5-------------- MAP_KINASE_ACTIVITY ( 0.0048164873763562 ); INACTIVATION_OF_MAPK_ACTIVITY ( 0.00561725860859519 ); NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY ( 0.00681735833992403 ); DNA_DAMAGE_CHECKPOINT ( 0.00801619055166014 ); DNA_INTEGRITY_CHECKPOINT ( 0.00921375639145716 ); PROTEIN_KINASE_INHIBITOR_ACTIVITY ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0000161 MAPKKK cascade during osmolarity sensing ( 0.00568582356953527 ); GO:0000173 inactivation of MAPK activity during osmolarity sensing ( 0.00851771756203085 ); GO:0016908 MAP kinase 2 activity ( 0.00568582356953527 ); GO:0007231 osmosensory signaling pathway ( 0.00851771756203085 ); GO:0019858 cytosine metabolic process ( 0.00568582356953527 ); GO:0001784 phosphotyrosine binding ( 0.00851771756203085 ); GO:0000165 MAPKKK cascade ( 0.00568582356953527 ); GO:0043330 response to exogenous dsRNA ( 0.00851771756203085 ); GO:0006206 pyrimidine base metabolic process ( 0.00568582356953527 ); GO:0050853 B cell receptor signaling pathway ( 0.00851771756203085 ); GO:0045309 protein phosphorylated amino acid binding ( 0.00568582356953527 ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( 0.00851771756203085 ); GO:0007049 cell cycle ( 0.00568582356953527 ); GO:0009628 response to abiotic stimulus ( 0.00851771756203085 ); GO:0043331 response to dsRNA ( 0.00568582356953527 ); GO:0051219 phosphoprotein binding ( 0.00851771756203085 ); GO:0031575 G1/S transition checkpoint ( 0.00568582356953527 ); GO:0004707 MAP kinase activity ( 0.00851771756203085 ); GO:0006970 response to osmotic stress ( 0.00568582356953527 ); GO:0050852 T cell receptor signaling pathway ( 0.00851771756203085 ); GO:0000724 double-strand break repair via homologous recombination ( 0.00568582356953527 ); GO:0000725 recombinational repair ( 0.00851771756203085 ); GO:0006974 response to DNA damage stimulus ( 0.00568582356953527 ); GO:0000188 inactivation of MAPK activity ( 0.00851771756203085 ); GO:0032496 response to lipopolysaccharide ( 0.00568582356953527 ); GO:0009112 nucleobase metabolic process ( 0.00851771756203085 ); GO:0050851 antigen receptor-mediated signaling pathway ( 0.00568582356953527 ); GO:0002237 response to molecule of bacterial origin ( 0.00851771756203085 ); GO:0008156 negative regulation of DNA replication ( 0.00568582356953527 ); GO:0004674 protein serine/threonine kinase activity ( 0.00851771756203085 ); ----------------GO-------------- GO:0000161 MAPKKK cascade during osmolarity sensing ( 0.00040215151058165 ); GO:0000173 inactivation of MAPK activity during osmolarity sensing ( 0.00040215151058165 ); GO:0016908 MAP kinase 2 activity ( 0.00040215151058165 ); GO:0007231 osmosensory signaling pathway ( 0.000804161503941581 ); GO:0019858 cytosine metabolic process ( 0.000804161503941581 ); GO:0001784 phosphotyrosine binding ( 0.00160775710973693 ); GO:0000165 MAPKKK cascade ( 0.00196528695300444 ); GO:0043330 response to exogenous dsRNA ( 0.00200934280751575 ); GO:0006206 pyrimidine base metabolic process ( 0.00281209020611339 ); GO:0050853 B cell receptor signaling pathway ( 0.00281209020611339 ); GO:0045309 protein phosphorylated amino acid binding ( 0.00281209020611339 ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( 0.00321325199221201 ); GO:0007049 cell cycle ( 0.00349762902705876 ); GO:0009628 response to abiotic stimulus ( 0.00352935141645545 ); GO:0043331 response to dsRNA ( 0.00441589020915356 ); GO:0051219 phosphoprotein binding ( 0.00441589020915356 ); GO:0031575 G1/S transition checkpoint ( 0.0048164873763562 ); GO:0004707 MAP kinase activity ( 0.00521694349531354 ); GO:0006970 response to osmotic stress ( 0.00561725860859519 ); GO:0050852 T cell receptor signaling pathway ( 0.00561725860859519 ); GO:0000724 double-strand break repair via homologous recombination ( 0.00601743275876021 ); GO:0000725 recombinational repair ( 0.00601743275876021 ); GO:0006974 response to DNA damage stimulus ( 0.00665210797152454 ); GO:0000188 inactivation of MAPK activity ( 0.00721710985598756 ); GO:0032496 response to lipopolysaccharide ( 0.0076167205790646 ); GO:0009112 nucleobase metabolic process ( 0.00801619055166014 ); GO:0050851 antigen receptor-mediated signaling pathway ( 0.00801619055166014 ); GO:0002237 response to molecule of bacterial origin ( 0.00961266378697145 ); GO:0008156 negative regulation of DNA replication ( 0.00961266378697145 ); GO:0004674 protein serine/threonine kinase activity ( 0.009878223455957 ); ----------------KEGG-------------- hsa05216 Thyroid cancer ( 0.0116050935415175 ); hsa04930 Type II diabetes mellitus ( 0.0163726217790504 ); hsa05219 Bladder cancer ( 0.016769005973377 ); hsa04150 mTOR signaling pathway ( 0.018748831152876 ); hsa05213 Endometrial cancer ( 0.0207251672154418 ); hsa05223 Non-small cell lung cancer ( 0.0215147258688544 ); hsa05221 Acute myeloid leukemia ( 0.0223037274442396 ); hsa05214 Glioma ( 0.0254541697016302 ); hsa05211 Renal cell carcinoma ( 0.0274186821606837 ); hsa04720 Long-term potentiation ( 0.0282035163789031 ); hsa05218 Melanoma ( 0.0282035163789031 ); hsa05212 Pancreatic cancer ( 0.028595725634728 ); hsa04370 VEGF signaling pathway ( 0.0289877963776229 ); hsa04730 Long-term depression ( 0.0293797286495191 ); hsa05220 Chronic myeloid leukemia ( 0.0293797286495191 ); hsa04520 Adherens junction ( 0.0297715224923372 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0301631779479862 ); hsa05210 Colorectal cancer ( 0.0332914446808504 ); hsa04012 ErbB signaling pathway ( 0.0340721304228946 ); hsa04350 TGF-beta signaling pathway ( 0.0340721304228946 ); hsa05215 Prostate cancer ( 0.0348522644575099 ); hsa04540 Gap junction ( 0.0379672902036493 ); hsa04912 GnRH signaling pathway ( 0.0391331548047936 ); hsa04620 Toll-like receptor signaling pathway ( 0.0395215015139767 ); hsa04916 Melanogenesis ( 0.0402977829454378 ); ----------------CARTA-------------- vifpathway ( 0.00200934280751575 ); gabapathway ( 0.00641746598835713 ); g2pathway ( 0.0108085429145913 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_C3 ( 0.00320482403222561 ); ARE_ALL ( 0.0194930816863581 ); ============================ group3183 ========================= ----------------C2-------------- REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING ( 0.0048164873763562 ); REACTOME_LYSOSOME_VESICLE_BIOGENESIS ( 0.00921375639145716 ); REACTOME_EGFR_DOWNREGULATION ( 0.00961266378697145 ); ----------------C3-------------- ( ); ----------------C4-------------- module_129 ( 0.00303411269790018 ); module_412 ( 0.00521694349531354 ); module_275 ( 0.00641746598835713 ); module_44 ( 0.00653055300204876 ); module_15 ( 0.00783673407616491 ); GNF2_TM4SF2 ( 0.00921375639145716 ); ----------------C5-------------- NEGATIVE_REGULATION_OF_CELL_ADHESION ( 0.00681735833992403 ); INTEGRIN_COMPLEX ( 0.00721710985598756 ); ----------------GOSLIM-------------- GO:0010872 regulation of cholesterol esterification ( ); GO:0010873 positive regulation of cholesterol esterification ( ); GO:0032372 negative regulation of sterol transport ( ); GO:0032375 negative regulation of cholesterol transport ( ); GO:0045717 negative regulation of fatty acid biosynthetic process ( ); GO:0045922 negative regulation of fatty acid metabolic process ( ); GO:0005094 Rho GDP-dissociation inhibitor activity ( ); GO:0034375 high-density lipoprotein particle remodeling ( ); GO:0034433 steroid esterification ( ); GO:0034434 sterol esterification ( ); GO:0034435 cholesterol esterification ( ); GO:0034447 very-low-density lipoprotein particle clearance ( ); GO:0051005 negative regulation of lipoprotein lipase activity ( ); GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity ( ); GO:0034379 very-low-density lipoprotein particle assembly ( ); GO:0048261 negative regulation of receptor-mediated endocytosis ( ); GO:0060192 negative regulation of lipase activity ( ); GO:0031210 phosphatidylcholine binding ( ); GO:0050995 negative regulation of lipid catabolic process ( ); GO:0005092 GDP-dissociation inhibitor activity ( ); GO:0034377 plasma lipoprotein particle assembly ( ); GO:0042304 regulation of fatty acid biosynthetic process ( ); GO:0045940 positive regulation of steroid metabolic process ( ); GO:0006897 endocytosis ( ); GO:0010324 membrane invagination ( ); GO:0032369 negative regulation of lipid transport ( ); GO:0051055 negative regulation of lipid biosynthetic process ( ); GO:0065005 protein-lipid complex assembly ( ); GO:0032371 regulation of sterol transport ( ); GO:0032374 regulation of cholesterol transport ( ); GO:0033700 phospholipid efflux ( ); GO:0050994 regulation of lipid catabolic process ( ); GO:0034361 very-low-density lipoprotein particle ( ); GO:0034385 triglyceride-rich lipoprotein particle ( ); GO:0034367 macromolecular complex remodeling ( ); GO:0034368 protein-lipid complex remodeling ( ); GO:0034369 plasma lipoprotein particle remodeling ( ); GO:0034381 lipoprotein particle clearance ( ); GO:0045806 negative regulation of endocytosis ( ); GO:0004859 phospholipase inhibitor activity ( ); GO:0048259 regulation of receptor-mediated endocytosis ( ); GO:0034364 high-density lipoprotein particle ( ); GO:0042627 chylomicron ( ); GO:0033344 cholesterol efflux ( ); GO:0051004 regulation of lipoprotein lipase activity ( ); GO:0032368 regulation of lipid transport ( ); GO:0055102 lipase inhibitor activity ( ); GO:0008047 enzyme activator activity ( ); GO:0045833 negative regulation of lipid metabolic process ( ); GO:0032994 protein-lipid complex ( ); GO:0034358 plasma lipoprotein particle ( ); GO:0016044 membrane organization ( ); GO:0009895 negative regulation of catabolic process ( ); GO:0019218 regulation of steroid metabolic process ( ); GO:0045834 positive regulation of lipid metabolic process ( ); GO:0032879 regulation of localization ( ); GO:0019217 regulation of fatty acid metabolic process ( ); GO:0046890 regulation of lipid biosynthetic process ( ); GO:0005504 fatty acid binding ( ); ----------------GO-------------- GO:0010872 regulation of cholesterol esterification ( 0.000804161503941581 ); GO:0010873 positive regulation of cholesterol esterification ( 0.000804161503941581 ); GO:0032372 negative regulation of sterol transport ( 0.00120603002276776 ); GO:0032375 negative regulation of cholesterol transport ( 0.00120603002276776 ); GO:0045717 negative regulation of fatty acid biosynthetic process ( 0.00120603002276776 ); GO:0045922 negative regulation of fatty acid metabolic process ( 0.00120603002276776 ); GO:0005094 Rho GDP-dissociation inhibitor activity ( 0.00120603002276776 ); GO:0034375 high-density lipoprotein particle remodeling ( 0.00160775710973693 ); GO:0034433 steroid esterification ( 0.00160775710973693 ); GO:0034434 sterol esterification ( 0.00160775710973693 ); GO:0034435 cholesterol esterification ( 0.00160775710973693 ); GO:0034447 very-low-density lipoprotein particle clearance ( 0.00160775710973693 ); GO:0051005 negative regulation of lipoprotein lipase activity ( 0.00160775710973693 ); GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity ( 0.00160775710973693 ); GO:0034379 very-low-density lipoprotein particle assembly ( 0.00200934280751575 ); GO:0048261 negative regulation of receptor-mediated endocytosis ( 0.00200934280751575 ); GO:0060192 negative regulation of lipase activity ( 0.00200934280751575 ); GO:0031210 phosphatidylcholine binding ( 0.00200934280751575 ); GO:0050995 negative regulation of lipid catabolic process ( 0.00241078715875964 ); GO:0005092 GDP-dissociation inhibitor activity ( 0.00241078715875964 ); GO:0034377 plasma lipoprotein particle assembly ( 0.00281209020611339 ); GO:0042304 regulation of fatty acid biosynthetic process ( 0.00281209020611339 ); GO:0045940 positive regulation of steroid metabolic process ( 0.00281209020611339 ); GO:0006897 endocytosis ( 0.00306225453876942 ); GO:0010324 membrane invagination ( 0.00306225453876942 ); GO:0032369 negative regulation of lipid transport ( 0.00321325199221201 ); GO:0051055 negative regulation of lipid biosynthetic process ( 0.00321325199221201 ); GO:0065005 protein-lipid complex assembly ( 0.00321325199221201 ); GO:0032371 regulation of sterol transport ( 0.00401515195112445 ); GO:0032374 regulation of cholesterol transport ( 0.00401515195112445 ); GO:0033700 phospholipid efflux ( 0.00401515195112445 ); GO:0050994 regulation of lipid catabolic process ( 0.00401515195112445 ); GO:0034361 very-low-density lipoprotein particle ( 0.00401515195112445 ); GO:0034385 triglyceride-rich lipoprotein particle ( 0.00401515195112445 ); GO:0034367 macromolecular complex remodeling ( 0.00441589020915356 ); GO:0034368 protein-lipid complex remodeling ( 0.00441589020915356 ); GO:0034369 plasma lipoprotein particle remodeling ( 0.00441589020915356 ); GO:0034381 lipoprotein particle clearance ( 0.00441589020915356 ); GO:0045806 negative regulation of endocytosis ( 0.00441589020915356 ); GO:0004859 phospholipase inhibitor activity ( 0.00441589020915356 ); GO:0048259 regulation of receptor-mediated endocytosis ( 0.0048164873763562 ); GO:0034364 high-density lipoprotein particle ( 0.0048164873763562 ); GO:0042627 chylomicron ( 0.0048164873763562 ); GO:0033344 cholesterol efflux ( 0.00521694349531354 ); GO:0051004 regulation of lipoprotein lipase activity ( 0.00521694349531354 ); GO:0032368 regulation of lipid transport ( 0.00561725860859519 ); GO:0055102 lipase inhibitor activity ( 0.00561725860859519 ); GO:0008047 enzyme activator activity ( 0.00625099959956006 ); GO:0045833 negative regulation of lipid metabolic process ( 0.00681735833992403 ); GO:0032994 protein-lipid complex ( 0.00721710985598756 ); GO:0034358 plasma lipoprotein particle ( 0.00721710985598756 ); GO:0016044 membrane organization ( 0.00757530615633847 ); GO:0009895 negative regulation of catabolic process ( 0.0076167205790646 ); GO:0019218 regulation of steroid metabolic process ( 0.00841551981626976 ); GO:0045834 positive regulation of lipid metabolic process ( 0.00841551981626976 ); GO:0032879 regulation of localization ( 0.00859967806156973 ); GO:0019217 regulation of fatty acid metabolic process ( 0.00881470841537757 ); GO:0046890 regulation of lipid biosynthetic process ( 0.00881470841537757 ); GO:0005504 fatty acid binding ( 0.00961266378697145 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3187 ========================= ----------------C2-------------- REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING ( 0.0048164873763562 ); REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS ( 0.00641746598835713 ); REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS ( 0.00841551981626976 ); REACTOME_EGFR_DOWNREGULATION ( 0.00961266378697145 ); ----------------C3-------------- V$PAX5_02 ( 0.0048164873763562 ); V$AHRARNT_02 ( 0.00521694349531354 ); ----------------C4-------------- module_253 ( 0.00841551981626976 ); module_196 ( 0.00921375639145716 ); ----------------C5-------------- NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.00401515195112445 ); REGULATION_OF_PROTEIN_POLYMERIZATION ( 0.00441589020915356 ); MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION ( 0.00441589020915356 ); PROTEIN_POLYMERIZATION ( 0.00721710985598756 ); CORTICAL_CYTOSKELETON ( 0.00801619055166014 ); CELL_CORTEX_PART ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0031115 negative regulation of microtubule polymerization ( ); GO:0030981 cortical microtubule cytoskeleton ( ); GO:0051010 microtubule plus-end binding ( ); GO:0031113 regulation of microtubule polymerization ( ); GO:0046785 microtubule polymerization ( ); GO:0050690 regulation of defense response to virus by virus ( ); GO:0031111 negative regulation of microtubule polymerization or depolymerization ( ); GO:0050688 regulation of defense response to virus ( ); GO:0031110 regulation of microtubule polymerization or depolymerization ( ); GO:0031109 microtubule polymerization or depolymerization ( ); GO:0043900 regulation of multi-organism process ( ); GO:0002831 regulation of response to biotic stimulus ( ); ----------------GO-------------- GO:0031115 negative regulation of microtubule polymerization ( 0.00040215151058165 ); GO:0030981 cortical microtubule cytoskeleton ( 0.000804161503941581 ); GO:0051010 microtubule plus-end binding ( 0.00120603002276776 ); GO:0031113 regulation of microtubule polymerization ( 0.00241078715875964 ); GO:0046785 microtubule polymerization ( 0.00321325199221201 ); GO:0050690 regulation of defense response to virus by virus ( 0.00321325199221201 ); GO:0031111 negative regulation of microtubule polymerization or depolymerization ( 0.00561725860859519 ); GO:0050688 regulation of defense response to virus ( 0.00561725860859519 ); GO:0031110 regulation of microtubule polymerization or depolymerization ( 0.00721710985598756 ); GO:0031109 microtubule polymerization or depolymerization ( 0.00841551981626976 ); GO:0043900 regulation of multi-organism process ( 0.00841551981626976 ); GO:0002831 regulation of response to biotic stimulus ( 0.00921375639145716 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0145981194654021 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3204 ========================= ----------------C2-------------- REACTOME_ETHANOL_OXIDATION ( 0.00401515195112445 ); REACTOME_PURINE_SALVAGE_REACTIONS ( 0.00441589020915356 ); BIOCARTA_EXTRINSIC_PATHWAY ( 0.00521694349531354 ); BIOCARTA_NUCLEARRS_PATHWAY ( 0.00561725860859519 ); REACTOME_COMMON_PATHWAY ( 0.00561725860859519 ); BIOCARTA_AMI_PATHWAY ( 0.0076167205790646 ); BIOCARTA_INTRINSIC_PATHWAY ( 0.00921375639145716 ); ----------------C3-------------- V$ARP1_01 ( 0.00098671888270403 ); V$TCF11MAFG_01 ( 0.00170097252957537 ); ----------------C4-------------- module_31 ( 0.00281209020611339 ); module_21 ( 0.00401515195112445 ); module_514 ( 0.00401515195112445 ); module_56 ( 0.0048164873763562 ); module_102 ( 0.00721710985598756 ); module_373 ( 0.00881470841537757 ); ----------------C5-------------- ALCOHOL_METABOLIC_PROCESS ( 0.000473797615495446 ); PURINE_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00441589020915356 ); BILE_ACID_METABOLIC_PROCESS ( 0.00441589020915356 ); PROTEIN_TETRAMERIZATION ( 0.00561725860859519 ); IDENTICAL_PROTEIN_BINDING ( 0.00593852278283656 ); BIOGENIC_AMINE_METABOLIC_PROCESS ( 0.00641746598835713 ); NUCLEOTIDE_BIOSYNTHETIC_PROCESS ( 0.00721710985598756 ); TRANSFERASE_ACTIVITY__TRANSFERRING_PENTOSYL_GROUPS ( 0.0076167205790646 ); PROTEIN_HOMOOLIGOMERIZATION ( 0.00881470841537757 ); AMINO_ACID_DERIVATIVE_METABOLIC_PROCESS ( 0.00921375639145716 ); REGULATION_OF_NEUROTRANSMITTER_LEVELS ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0010033 response to organic substance ( 0.0050293559368679 ); GO:0050896 response to stimulus ( 0.00531209660878121 ); GO:0006178 guanine salvage ( 0.0050293559368679 ); GO:0010430 fatty acid omega-oxidation ( 0.00531209660878121 ); GO:0033240 positive regulation of cellular amine metabolic process ( 0.0050293559368679 ); GO:0045915 positive regulation of catecholamine metabolic process ( 0.00531209660878121 ); GO:0045964 positive regulation of dopamine metabolic process ( 0.0050293559368679 ); GO:0046098 guanine metabolic process ( 0.00531209660878121 ); GO:0035276 ethanol binding ( 0.0050293559368679 ); GO:0006168 adenine salvage ( 0.00531209660878121 ); GO:0043096 purine base salvage ( 0.0050293559368679 ); GO:0046083 adenine metabolic process ( 0.00531209660878121 ); GO:0042587 glycogen granule ( 0.0050293559368679 ); GO:0004031 aldehyde oxidase activity ( 0.00531209660878121 ); GO:0004105 choline-phosphate cytidylyltransferase activity ( 0.0050293559368679 ); GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor ( 0.00531209660878121 ); GO:0046100 hypoxanthine metabolic process ( 0.0050293559368679 ); GO:0002054 nucleobase binding ( 0.00531209660878121 ); GO:0002060 purine binding ( 0.0050293559368679 ); GO:0004422 hypoxanthine phosphoribosyltransferase activity ( 0.00531209660878121 ); GO:0044255 cellular lipid metabolic process ( 0.0050293559368679 ); GO:0006067 ethanol metabolic process ( 0.00531209660878121 ); GO:0006069 ethanol oxidation ( 0.0050293559368679 ); GO:0006166 purine ribonucleoside salvage ( 0.00531209660878121 ); GO:0034308 monohydric alcohol metabolic process ( 0.0050293559368679 ); GO:0043174 nucleoside salvage ( 0.00531209660878121 ); GO:0043178 alcohol binding ( 0.0050293559368679 ); GO:0007625 grooming behavior ( 0.00531209660878121 ); GO:0042053 regulation of dopamine metabolic process ( 0.0050293559368679 ); GO:0042069 regulation of catecholamine metabolic process ( 0.00531209660878121 ); GO:0043101 purine salvage ( 0.0050293559368679 ); GO:0004024 alcohol dehydrogenase activity, zinc-dependent ( 0.00531209660878121 ); GO:0032052 bile acid binding ( 0.0050293559368679 ); GO:0042221 response to chemical stimulus ( 0.00531209660878121 ); GO:0021895 cerebral cortex neuron differentiation ( 0.0050293559368679 ); GO:0033238 regulation of cellular amine metabolic process ( 0.00531209660878121 ); GO:0006629 lipid metabolic process ( 0.0050293559368679 ); GO:0005625 soluble fraction ( 0.00531209660878121 ); GO:0001975 response to amphetamine ( 0.0050293559368679 ); GO:0021756 striatum development ( 0.00531209660878121 ); GO:0043094 cellular metabolic compound salvage ( 0.0050293559368679 ); GO:0048813 dendrite morphogenesis ( 0.00531209660878121 ); GO:0051289 protein homotetramerization ( 0.0050293559368679 ); GO:0004022 alcohol dehydrogenase activity ( 0.00531209660878121 ); GO:0009628 response to abiotic stimulus ( 0.0050293559368679 ); GO:0021544 subpallium development ( 0.00531209660878121 ); GO:0004745 retinol dehydrogenase activity ( 0.0050293559368679 ); GO:0006656 phosphatidylcholine biosynthetic process ( 0.00531209660878121 ); GO:0042278 purine nucleoside metabolic process ( 0.0050293559368679 ); GO:0046128 purine ribonucleoside metabolic process ( 0.00531209660878121 ); GO:0030547 receptor inhibitor activity ( 0.0050293559368679 ); GO:0048019 receptor antagonist activity ( 0.00531209660878121 ); GO:0032787 monocarboxylic acid metabolic process ( 0.0050293559368679 ); GO:0010243 response to organic nitrogen ( 0.00531209660878121 ); GO:0014075 response to amine stimulus ( 0.0050293559368679 ); GO:0019841 retinol binding ( 0.00531209660878121 ); GO:0031406 carboxylic acid binding ( 0.0050293559368679 ); GO:0001523 retinoid metabolic process ( 0.00531209660878121 ); GO:0009119 ribonucleoside metabolic process ( 0.0050293559368679 ); GO:0009746 response to hexose stimulus ( 0.00531209660878121 ); GO:0009749 response to glucose stimulus ( 0.0050293559368679 ); GO:0016101 diterpenoid metabolic process ( 0.00531209660878121 ); GO:0034284 response to monosaccharide stimulus ( 0.0050293559368679 ); GO:0006144 purine base metabolic process ( 0.00531209660878121 ); GO:0008206 bile acid metabolic process ( 0.0050293559368679 ); GO:0006721 terpenoid metabolic process ( 0.00531209660878121 ); GO:0042417 dopamine metabolic process ( 0.0050293559368679 ); GO:0046470 phosphatidylcholine metabolic process ( 0.00531209660878121 ); GO:0006066 cellular alcohol metabolic process ( 0.0050293559368679 ); GO:0051173 positive regulation of nitrogen compound metabolic process ( 0.00531209660878121 ); GO:0002020 protease binding ( 0.0050293559368679 ); GO:0009743 response to carbohydrate stimulus ( 0.00531209660878121 ); GO:0051262 protein tetramerization ( 0.0050293559368679 ); GO:0021954 central nervous system neuron development ( 0.00531209660878121 ); GO:0032496 response to lipopolysaccharide ( 0.0050293559368679 ); GO:0005501 retinoid binding ( 0.00531209660878121 ); GO:0019840 isoprenoid binding ( 0.0050293559368679 ); GO:0009112 nucleobase metabolic process ( 0.00531209660878121 ); GO:0045471 response to ethanol ( 0.0050293559368679 ); GO:0006109 regulation of carbohydrate metabolic process ( 0.00531209660878121 ); GO:0016358 dendrite development ( 0.0050293559368679 ); GO:0021953 central nervous system neuron differentiation ( 0.00531209660878121 ); GO:0048565 gut development ( 0.0050293559368679 ); GO:0002237 response to molecule of bacterial origin ( 0.00531209660878121 ); GO:0019835 cytolysis ( 0.0050293559368679 ); ----------------GO-------------- GO:0010033 response to organic substance ( 6.3772320363379e-06 ); GO:0050896 response to stimulus ( 0.000148137320501705 ); GO:0006178 guanine salvage ( 0.00040215151058165 ); GO:0010430 fatty acid omega-oxidation ( 0.00040215151058165 ); GO:0033240 positive regulation of cellular amine metabolic process ( 0.00040215151058165 ); GO:0045915 positive regulation of catecholamine metabolic process ( 0.00040215151058165 ); GO:0045964 positive regulation of dopamine metabolic process ( 0.00040215151058165 ); GO:0046098 guanine metabolic process ( 0.00040215151058165 ); GO:0035276 ethanol binding ( 0.00040215151058165 ); GO:0006168 adenine salvage ( 0.000804161503941581 ); GO:0043096 purine base salvage ( 0.000804161503941581 ); GO:0046083 adenine metabolic process ( 0.000804161503941581 ); GO:0042587 glycogen granule ( 0.000804161503941581 ); GO:0004031 aldehyde oxidase activity ( 0.000804161503941581 ); GO:0004105 choline-phosphate cytidylyltransferase activity ( 0.000804161503941581 ); GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor ( 0.000804161503941581 ); GO:0046100 hypoxanthine metabolic process ( 0.00120603002276776 ); GO:0002054 nucleobase binding ( 0.00120603002276776 ); GO:0002060 purine binding ( 0.00120603002276776 ); GO:0004422 hypoxanthine phosphoribosyltransferase activity ( 0.00120603002276776 ); GO:0044255 cellular lipid metabolic process ( 0.00124993333905196 ); GO:0006067 ethanol metabolic process ( 0.00160775710973693 ); GO:0006069 ethanol oxidation ( 0.00160775710973693 ); GO:0006166 purine ribonucleoside salvage ( 0.00160775710973693 ); GO:0034308 monohydric alcohol metabolic process ( 0.00160775710973693 ); GO:0043174 nucleoside salvage ( 0.00160775710973693 ); GO:0043178 alcohol binding ( 0.00160775710973693 ); GO:0007625 grooming behavior ( 0.00200934280751575 ); GO:0042053 regulation of dopamine metabolic process ( 0.00200934280751575 ); GO:0042069 regulation of catecholamine metabolic process ( 0.00200934280751575 ); GO:0043101 purine salvage ( 0.00200934280751575 ); GO:0004024 alcohol dehydrogenase activity, zinc-dependent ( 0.00200934280751575 ); GO:0032052 bile acid binding ( 0.00200934280751575 ); GO:0042221 response to chemical stimulus ( 0.00233462121012026 ); GO:0021895 cerebral cortex neuron differentiation ( 0.00241078715875964 ); GO:0033238 regulation of cellular amine metabolic process ( 0.00241078715875964 ); GO:0006629 lipid metabolic process ( 0.00243779900392181 ); GO:0005625 soluble fraction ( 0.00262693362988407 ); GO:0001975 response to amphetamine ( 0.00321325199221201 ); GO:0021756 striatum development ( 0.00321325199221201 ); GO:0043094 cellular metabolic compound salvage ( 0.00321325199221201 ); GO:0048813 dendrite morphogenesis ( 0.00321325199221201 ); GO:0051289 protein homotetramerization ( 0.00321325199221201 ); GO:0004022 alcohol dehydrogenase activity ( 0.00321325199221201 ); GO:0009628 response to abiotic stimulus ( 0.00352935141645545 ); GO:0021544 subpallium development ( 0.00361427255967794 ); GO:0004745 retinol dehydrogenase activity ( 0.00361427255967794 ); GO:0006656 phosphatidylcholine biosynthetic process ( 0.00401515195112445 ); GO:0042278 purine nucleoside metabolic process ( 0.00401515195112445 ); GO:0046128 purine ribonucleoside metabolic process ( 0.00401515195112445 ); GO:0030547 receptor inhibitor activity ( 0.00401515195112445 ); GO:0048019 receptor antagonist activity ( 0.00401515195112445 ); GO:0032787 monocarboxylic acid metabolic process ( 0.00402790267061662 ); GO:0010243 response to organic nitrogen ( 0.00441589020915356 ); GO:0014075 response to amine stimulus ( 0.00441589020915356 ); GO:0019841 retinol binding ( 0.0048164873763562 ); GO:0031406 carboxylic acid binding ( 0.0048164873763562 ); GO:0001523 retinoid metabolic process ( 0.00521694349531354 ); GO:0009119 ribonucleoside metabolic process ( 0.00521694349531354 ); GO:0009746 response to hexose stimulus ( 0.00521694349531354 ); GO:0009749 response to glucose stimulus ( 0.00521694349531354 ); GO:0016101 diterpenoid metabolic process ( 0.00521694349531354 ); GO:0034284 response to monosaccharide stimulus ( 0.00521694349531354 ); GO:0006144 purine base metabolic process ( 0.00561725860859519 ); GO:0008206 bile acid metabolic process ( 0.00561725860859519 ); GO:0006721 terpenoid metabolic process ( 0.00601743275876021 ); GO:0042417 dopamine metabolic process ( 0.00601743275876021 ); GO:0046470 phosphatidylcholine metabolic process ( 0.00601743275876021 ); GO:0006066 cellular alcohol metabolic process ( 0.00605482271146932 ); GO:0051173 positive regulation of nitrogen compound metabolic process ( 0.00641746598835713 ); GO:0002020 protease binding ( 0.00641746598835713 ); GO:0009743 response to carbohydrate stimulus ( 0.00721710985598756 ); GO:0051262 protein tetramerization ( 0.00721710985598756 ); GO:0021954 central nervous system neuron development ( 0.0076167205790646 ); GO:0032496 response to lipopolysaccharide ( 0.0076167205790646 ); GO:0005501 retinoid binding ( 0.0076167205790646 ); GO:0019840 isoprenoid binding ( 0.0076167205790646 ); GO:0009112 nucleobase metabolic process ( 0.00801619055166014 ); GO:0045471 response to ethanol ( 0.00801619055166014 ); GO:0006109 regulation of carbohydrate metabolic process ( 0.00841551981626976 ); GO:0016358 dendrite development ( 0.00881470841537757 ); GO:0021953 central nervous system neuron differentiation ( 0.00881470841537757 ); GO:0048565 gut development ( 0.00881470841537757 ); GO:0002237 response to molecule of bacterial origin ( 0.00961266378697145 ); GO:0019835 cytolysis ( 0.00961266378697145 ); ----------------KEGG-------------- hsa00440 Aminophosphonate metabolism ( 0.00441589020915356 ); hsa00624 1- and 2-Methylnaphthalene degradation ( 0.0048164873763562 ); hsa00641 3-Chloroacrylic acid degradation ( 0.00561725860859519 ); hsa00120 Bile acid biosynthesis ( 0.0127988671427596 ); hsa00983 Drug metabolism - other enzymes ( 0.0175613550768865 ); hsa00350 Tyrosine metabolism ( 0.0179573200705576 ); hsa00071 Fatty acid metabolism ( 0.0183531454151488 ); hsa00830 Retinol metabolism ( 0.0223037274442396 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.0246673930707164 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0246673930707164 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0254541697016302 ); hsa00564 Glycerophospholipid metabolism ( 0.0258473497229316 ); hsa04610 Complement and coagulation cascades ( 0.0270260571143742 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3238 ========================= ----------------C2-------------- REACTOME_SIGNALING_IN_IMMUNE_SYSTEM ( 0.00714875613343667 ); REACTOME_MYD88_CASCADE ( 0.0076167205790646 ); REACTOME_TRANSLOCATION_OF_ZAP70_TO_IMMUNOLOGICAL_SYNAPSE ( 0.00801619055166014 ); REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS ( 0.00881470841537757 ); REACTOME_TOLL_LIKE_RECEPTOR_9_CASCADE ( 0.00921375639145716 ); REACTOME_SMOOTH_MUSCLE_CONTRACTION ( 0.00921375639145716 ); REACTOME_ACTIVATED_TLR4_SIGNALLING ( 0.00961266378697145 ); ----------------C3-------------- CACCAGC,MIR-138 ( 0.00203424059749427 ); TTTTGAG,MIR-373 ( 0.00242129020600337 ); V$TTF1_Q6 ( 0.00247194651149353 ); CCCNNGGGAR_V$OLF1_01 ( 0.00374361611710857 ); CATTGTYY_V$SOX9_B1 ( 0.00497509425144873 ); ----------------C4-------------- ( ); ----------------C5-------------- STRUCTURAL_MOLECULE_ACTIVITY ( 0.00393204310720248 ); UNFOLDED_PROTEIN_RESPONSE ( 0.00401515195112445 ); BETA_TUBULIN_BINDING ( 0.00401515195112445 ); REGULATION_OF_VIRAL_REPRODUCTION ( 0.0048164873763562 ); SARCOMERE ( 0.00561725860859519 ); ER_NUCLEAR_SIGNALING_PATHWAY ( 0.00641746598835713 ); INTERACTION_WITH_HOST ( 0.00681735833992403 ); MYOFIBRIL ( 0.0076167205790646 ); VIRAL_GENOME_REPLICATION ( 0.00841551981626976 ); CYTOSKELETON ( 0.00846266329276749 ); CONTRACTILE_FIBER_PART ( 0.00921375639145716 ); ----------------GOSLIM-------------- GO:0008092 cytoskeletal protein binding ( 0.000953369274137623 ); GO:0005198 structural molecule activity ( 0.00493999687317193 ); GO:0045070 positive regulation of viral genome replication ( 0.000953369274137623 ); GO:0007249 I-kappaB kinase/NF-kappaB cascade ( 0.00493999687317193 ); GO:0005862 muscle thin filament tropomyosin ( 0.000953369274137623 ); GO:0048524 positive regulation of viral reproduction ( 0.00493999687317193 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.000953369274137623 ); GO:0019048 virus-host interaction ( 0.00493999687317193 ); GO:0032395 MHC class II receptor activity ( 0.000953369274137623 ); GO:0048487 beta-tubulin binding ( 0.00493999687317193 ); GO:0045069 regulation of viral genome replication ( 0.000953369274137623 ); GO:0005865 striated muscle thin filament ( 0.00493999687317193 ); GO:0042613 MHC class II protein complex ( 0.000953369274137623 ); GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ( 0.00493999687317193 ); GO:0050792 regulation of viral reproduction ( 0.000953369274137623 ); GO:0015026 coreceptor activity ( 0.00493999687317193 ); GO:0030968 endoplasmic reticulum unfolded protein response ( 0.000953369274137623 ); GO:0034620 cellular response to unfolded protein ( 0.00493999687317193 ); GO:0051701 interaction with host ( 0.000953369274137623 ); ----------------GO-------------- GO:0008092 cytoskeletal protein binding ( 0.000497159685742645 ); GO:0005198 structural molecule activity ( 0.000963383068698091 ); GO:0045070 positive regulation of viral genome replication ( 0.00120603002276776 ); GO:0007249 I-kappaB kinase/NF-kappaB cascade ( 0.00132037403499766 ); GO:0005862 muscle thin filament tropomyosin ( 0.00160775710973693 ); GO:0048524 positive regulation of viral reproduction ( 0.00241078715875964 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.00321325199221201 ); GO:0019048 virus-host interaction ( 0.00361427255967794 ); GO:0032395 MHC class II receptor activity ( 0.00361427255967794 ); GO:0048487 beta-tubulin binding ( 0.00361427255967794 ); GO:0045069 regulation of viral genome replication ( 0.0048164873763562 ); GO:0005865 striated muscle thin filament ( 0.0048164873763562 ); GO:0042613 MHC class II protein complex ( 0.0048164873763562 ); GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ( 0.00641746598835713 ); GO:0050792 regulation of viral reproduction ( 0.00641746598835713 ); GO:0015026 coreceptor activity ( 0.00721710985598756 ); GO:0030968 endoplasmic reticulum unfolded protein response ( 0.0076167205790646 ); GO:0034620 cellular response to unfolded protein ( 0.0076167205790646 ); GO:0051701 interaction with host ( 0.00881470841537757 ); ----------------KEGG-------------- hsa05310 Asthma ( 0.0108085429145913 ); hsa05330 Allograft rejection ( 0.0139913789540209 ); hsa05332 Graft-versus-host disease ( 0.015579433893953 ); hsa04940 Type I diabetes mellitus ( 0.0159760977666663 ); hsa05320 Autoimmune thyroid disease ( 0.0195397839765594 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0203301788791369 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0203301788791369 ); hsa04612 Antigen processing and presentation ( 0.0329008948150514 ); hsa04620 Toll-like receptor signaling pathway ( 0.0395215015139767 ); hsa05322 Systemic lupus erythematosus ( 0.0495704302140182 ); ----------------CARTA-------------- il10pathway ( 0.00961266378697145 ); ptdinspathway ( 0.0112068884122597 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 0.0239577391041987 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0243342988662651 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0243613438251602 ); TIAL1_iCLIP_(Wang_2010) ( 0.042358967328839 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3248 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- INTERLEUKIN_RECEPTOR_ACTIVITY ( 0.0076167205790646 ); INTERLEUKIN_BINDING ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0004919 interleukin-9 receptor activity ( ); GO:0019983 interleukin-9 binding ( ); GO:0030280 structural constituent of epidermis ( ); ----------------GO-------------- GO:0004919 interleukin-9 receptor activity ( 0.00040215151058165 ); GO:0019983 interleukin-9 binding ( 0.00040215151058165 ); GO:0030280 structural constituent of epidermis ( 0.00321325199221201 ); ----------------KEGG-------------- ( 0.0332914446808504 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3445 ========================= ----------------C2-------------- REACTOME_HIV_INFECTION ( 0.00224796704265788 ); REACTOME_RNA_POLYMERASE_III_CHAIN_ELONGATION ( 0.0048164873763562 ); REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS ( 0.00561725860859519 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION ( 0.00681735833992403 ); REACTOME_MICRORNA_BIOGENESIS ( 0.00721710985598756 ); BIOCARTA_PROTEASOME_PATHWAY ( 0.0076167205790646 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER ( 0.00801619055166014 ); REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER ( 0.00881470841537757 ); REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT ( 0.00921375639145716 ); ----------------C3-------------- ( ); ----------------C4-------------- module_50 ( 0.00521694349531354 ); module_83 ( 0.00589999096391577 ); module_81 ( 0.0076167205790646 ); ----------------C5-------------- DNA_DIRECTED_RNA_POLYMERASE_II__CORE_COMPLEX ( 0.0048164873763562 ); RNA_POLYMERASE_ACTIVITY ( 0.00641746598835713 ); DNA_DIRECTED_RNA_POLYMERASE_COMPLEX ( 0.00681735833992403 ); RNA_POLYMERASE_COMPLEX ( 0.00681735833992403 ); NUCLEAR_DNA_DIRECTED_RNA_POLYMERASE_COMPLEX ( 0.00681735833992403 ); ----------------GOSLIM-------------- GO:0044419 interspecies interaction between organisms ( 0.00878394218872406 ); GO:0008380 RNA splicing ( 0.00878394218872406 ); GO:0005665 DNA-directed RNA polymerase II, core complex ( 0.00878394218872406 ); GO:0006397 mRNA processing ( 0.00878394218872406 ); GO:0016071 mRNA metabolic process ( 0.00878394218872406 ); GO:0005839 proteasome core complex ( 0.00878394218872406 ); GO:0004298 threonine-type endopeptidase activity ( 0.00878394218872406 ); GO:0070003 threonine-type peptidase activity ( 0.00878394218872406 ); GO:0000428 DNA-directed RNA polymerase complex ( 0.00878394218872406 ); GO:0055029 nuclear DNA-directed RNA polymerase complex ( 0.00878394218872406 ); GO:0030880 RNA polymerase complex ( 0.00878394218872406 ); ----------------GO-------------- GO:0044419 interspecies interaction between organisms ( 0.0038059366624902 ); GO:0008380 RNA splicing ( 0.004799035529206 ); GO:0005665 DNA-directed RNA polymerase II, core complex ( 0.00561725860859519 ); GO:0006397 mRNA processing ( 0.00570909647806328 ); GO:0016071 mRNA metabolic process ( 0.0071067334401918 ); GO:0005839 proteasome core complex ( 0.0076167205790646 ); GO:0004298 threonine-type endopeptidase activity ( 0.00801619055166014 ); GO:0070003 threonine-type peptidase activity ( 0.00801619055166014 ); GO:0000428 DNA-directed RNA polymerase complex ( 0.00881470841537757 ); GO:0055029 nuclear DNA-directed RNA polymerase complex ( 0.00881470841537757 ); GO:0030880 RNA polymerase complex ( 0.00961266378697145 ); ----------------KEGG-------------- hsa03020 RNA polymerase ( 0.0100114306443726 ); hsa03050 Proteasome ( 0.0175613550768865 ); hsa00240 Pyrimidine metabolism ( 0.0360214317890752 ); ----------------CARTA-------------- rhopathway ( 0.0048164873763562 ); nkcellspathway ( 0.00881470841537757 ); no1pathway ( 0.015579433893953 ); ----------------RBP-------------- AGO2_PAR-CLIP_(Kishore_2011) ( 7.97802769719759e-06 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 1.16456231663391e-05 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.000179832569054867 ); AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00102234920058351 ); TIAL1_iCLIP_(Wang_2010) ( 0.042358967328839 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3611 ========================= ----------------C2-------------- KEGG_RIBOFLAVIN_METABOLISM ( 0.00641746598835713 ); BIOCARTA_NDKDYNAMIN_PATHWAY ( 0.00721710985598756 ); REACTOME_EGFR_DOWNREGULATION ( 0.00961266378697145 ); ----------------C3-------------- V$SP1_Q6_01 ( 0.00183082538027867 ); V$SP1_Q6 ( 0.00210433993231834 ); V$STAT4_01 ( 0.00242129020600337 ); V$STAT6_02 ( 0.00244655538690318 ); V$MAF_Q6 ( 0.00270612100091895 ); V$MEF2_04 ( 0.00841551981626976 ); ----------------C4-------------- ( 0.00921375639145716 ); ----------------C5-------------- TRNA_PROCESSING ( 0.00401515195112445 ); PROTEIN_TARGETING_TO_MITOCHONDRION ( 0.00401515195112445 ); RNA_3__END_PROCESSING ( 0.00401515195112445 ); INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHATASE_ACTIVITY ( 0.00441589020915356 ); TRNA_METABOLIC_PROCESS ( 0.00721710985598756 ); MITOCHONDRIAL_TRANSPORT ( 0.00801619055166014 ); EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY ( 0.00881470841537757 ); ----------------GOSLIM-------------- GO:0042780 tRNA 3'-end processing ( ); GO:0043628 ncRNA 3'-end processing ( ); GO:0004810 tRNA adenylyltransferase activity ( ); GO:0050291 sphingosine N-acyltransferase activity ( ); GO:0046513 ceramide biosynthetic process ( ); GO:0046520 sphingoid biosynthetic process ( ); GO:0031123 RNA 3'-end processing ( ); GO:0000049 tRNA binding ( ); GO:0030148 sphingolipid biosynthetic process ( ); GO:0006626 protein targeting to mitochondrion ( ); GO:0004437 inositol or phosphatidylinositol phosphatase activity ( ); GO:0031901 early endosome membrane ( ); ----------------GO-------------- GO:0042780 tRNA 3'-end processing ( 0.00040215151058165 ); GO:0043628 ncRNA 3'-end processing ( 0.00040215151058165 ); GO:0004810 tRNA adenylyltransferase activity ( 0.00040215151058165 ); GO:0050291 sphingosine N-acyltransferase activity ( 0.00160775710973693 ); GO:0046513 ceramide biosynthetic process ( 0.00321325199221201 ); GO:0046520 sphingoid biosynthetic process ( 0.00361427255967794 ); GO:0031123 RNA 3'-end processing ( 0.00601743275876021 ); GO:0000049 tRNA binding ( 0.00641746598835713 ); GO:0030148 sphingolipid biosynthetic process ( 0.00841551981626976 ); GO:0006626 protein targeting to mitochondrion ( 0.00921375639145716 ); GO:0004437 inositol or phosphatidylinositol phosphatase activity ( 0.00921375639145716 ); GO:0031901 early endosome membrane ( 0.00961266378697145 ); ----------------KEGG-------------- hsa00730 Thiamine metabolism ( 0.00281209020611339 ); hsa00740 Riboflavin metabolism ( 0.00601743275876021 ); hsa00530 Aminosugars metabolism ( 0.0120031583447628 ); hsa00051 Fructose and mannose metabolism ( 0.0139913789540209 ); hsa04662 B cell receptor signaling pathway ( 0.0258473497229316 ); hsa04370 VEGF signaling pathway ( 0.0289877963776229 ); hsa04660 T cell receptor signaling pathway ( 0.0371893596581885 ); ----------------CARTA-------------- ( 0.00961266378697145 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Mukherjee_2011) ( 1.4867445788825e-05 ); ELAVL1_PAR-CLIP_(Lebedeva_2011) ( 0.000156038690883117 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.000300086645011286 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0033947394417412 ); TIAL1_iCLIP_(Wang_2010) ( 0.00582801082623543 ); ----------------immu-------------- BCR_signalling_pathway ( 0.0293797286495191 ); TCR_signalling_pathway ( 0.0383560491912923 ); ----------------ARE-------------- ( ); ============================ group3659 ========================= ----------------C2-------------- BIOCARTA_CFTR_PATHWAY ( 0.0048164873763562 ); BIOCARTA_PLCE_PATHWAY ( 0.0048164873763562 ); REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS ( 0.00540980113330542 ); BIOCARTA_GCR_PATHWAY ( 0.0076167205790646 ); REACTOME_GPCR_LIGAND_BINDING ( 0.00968368085457561 ); ----------------C3-------------- CAGGTA_V$AREB6_01 ( 0.00117677506302946 ); V$TGIF_01 ( 0.00196528695300444 ); V$P300_01 ( 0.00222371227489467 ); V$LHX3_01 ( 0.00227234839075581 ); ----------------C4-------------- module_289 ( 0.000922509690951717 ); module_454 ( 0.00401515195112445 ); module_196 ( 0.00921375639145716 ); ----------------C5-------------- LYSOSOMAL_TRANSPORT ( 0.00401515195112445 ); POSITIVE_REGULATION_OF_MAPKKK_CASCADE ( 0.00441589020915356 ); NEUROPEPTIDE_HORMONE_ACTIVITY ( 0.00441589020915356 ); VACUOLAR_TRANSPORT ( 0.00521694349531354 ); HORMONE_BINDING ( 0.00521694349531354 ); ADENYLATE_CYCLASE_ACTIVATION ( 0.00721710985598756 ); REGULATION_OF_MAPKKK_CASCADE ( 0.00801619055166014 ); REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY ( 0.00921375639145716 ); ENDOSOME_TRANSPORT ( 0.00921375639145716 ); AMINE_BINDING ( 0.00921375639145716 ); G_PROTEIN_SIGNALING__ADENYLATE_CYCLASE_ACTIVATING_PATHWAY ( 0.00961266378697145 ); ----------------GOSLIM-------------- GO:0021519 spinal cord association neuron specification ( ); GO:0021920 regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification ( ); GO:0048631 regulation of skeletal muscle growth ( ); GO:0048633 positive regulation of skeletal muscle growth ( ); GO:0004941 beta2-adrenergic receptor activity ( ); GO:0007519 skeletal muscle development ( ); GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin ( ); GO:0034204 lipid translocation ( ); GO:0045332 phospholipid translocation ( ); GO:0048643 positive regulation of skeletal muscle development ( ); GO:0008179 adenylate cyclase binding ( ); GO:0051380 norepinephrine binding ( ); GO:0014706 striated muscle development ( ); GO:0002024 diet induced thermogenesis ( ); GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure ( ); GO:0032091 negative regulation of protein binding ( ); GO:0045844 positive regulation of striated muscle development ( ); GO:0045986 negative regulation of smooth muscle contraction ( ); GO:0048630 skeletal muscle growth ( ); GO:0048636 positive regulation of muscle development ( ); GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity ( ); GO:0004939 beta-adrenergic receptor activity ( ); GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity ( ); GO:0021527 spinal cord association neuron differentiation ( ); GO:0032410 negative regulation of transporter activity ( ); GO:0032413 negative regulation of ion transmembrane transporter activity ( ); GO:0051930 regulation of sensory perception of pain ( ); GO:0051931 regulation of sensory perception ( ); GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway ( ); GO:0022401 adaptation of signaling pathway ( ); GO:0031649 heat generation ( ); GO:0048639 positive regulation of developmental growth ( ); GO:0048664 neuron fate determination ( ); GO:0001515 opioid peptide activity ( ); GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine ( ); GO:0040015 negative regulation of multicellular organism growth ( ); GO:0045932 negative regulation of muscle contraction ( ); GO:0050873 brown fat cell differentiation ( ); GO:0007517 muscle development ( ); GO:0008333 endosome to lysosome transport ( ); GO:0044253 positive regulation of multicellular organismal metabolic process ( ); GO:0045909 positive regulation of vasodilation ( ); GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity ( ); GO:0051926 negative regulation of calcium ion transport ( ); GO:0003085 negative regulation of systemic arterial blood pressure ( ); GO:0021516 dorsal spinal cord development ( ); GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway ( ); GO:0048638 regulation of developmental growth ( ); GO:0002021 response to dietary excess ( ); GO:0002028 regulation of sodium ion transport ( ); GO:0044246 regulation of multicellular organismal metabolic process ( ); GO:0045823 positive regulation of heart contraction ( ); GO:0004935 adrenoceptor activity ( ); GO:0030279 negative regulation of ossification ( ); GO:0043271 negative regulation of ion transport ( ); GO:0009165 nucleotide biosynthetic process ( ); GO:0045776 negative regulation of blood pressure ( ); GO:0000299 integral to membrane of membrane fraction ( ); GO:0001659 temperature homeostasis ( ); GO:0048665 neuron fate specification ( ); GO:0009409 response to cold ( ); GO:0042312 regulation of vasodilation ( ); GO:0046851 negative regulation of bone remodeling ( ); GO:0007339 binding of sperm to zona pellucida ( ); GO:0035036 sperm-egg recognition ( ); GO:0050728 negative regulation of inflammatory response ( ); GO:0007041 lysosomal transport ( ); GO:0030501 positive regulation of bone mineralization ( ); GO:0031348 negative regulation of defense response ( ); GO:0034104 negative regulation of tissue remodeling ( ); GO:0048641 regulation of skeletal muscle development ( ); GO:0004012 phospholipid-translocating ATPase activity ( ); GO:0015247 aminophospholipid transporter activity ( ); GO:0070169 positive regulation of biomineral formation ( ); GO:0006753 nucleoside phosphate metabolic process ( ); GO:0009117 nucleotide metabolic process ( ); GO:0001947 heart looping ( ); GO:0009988 cell-cell recognition ( ); GO:0045453 bone resorption ( ); GO:0021515 cell differentiation in spinal cord ( ); GO:0043393 regulation of protein binding ( ); GO:0055086 nucleobase, nucleoside and nucleotide metabolic process ( ); GO:0016044 membrane organization ( ); GO:0022898 regulation of transmembrane transporter activity ( ); GO:0032409 regulation of transporter activity ( ); GO:0032412 regulation of ion transmembrane transporter activity ( ); GO:0045778 positive regulation of ossification ( ); GO:0005184 neuropeptide hormone activity ( ); GO:0006940 regulation of smooth muscle contraction ( ); GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( ); GO:0005901 caveola ( ); GO:0015459 potassium channel regulator activity ( ); GO:0007034 vacuolar transport ( ); GO:0032102 negative regulation of response to external stimulus ( ); GO:0046852 positive regulation of bone remodeling ( ); GO:0030500 regulation of bone mineralization ( ); GO:0034105 positive regulation of tissue remodeling ( ); GO:0001708 cell fate specification ( ); GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ( ); GO:0045665 negative regulation of neuron differentiation ( ); ----------------GO-------------- GO:0021519 spinal cord association neuron specification ( 0.00040215151058165 ); GO:0021920 regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification ( 0.00040215151058165 ); GO:0048631 regulation of skeletal muscle growth ( 0.00040215151058165 ); GO:0048633 positive regulation of skeletal muscle growth ( 0.00040215151058165 ); GO:0004941 beta2-adrenergic receptor activity ( 0.00040215151058165 ); GO:0007519 skeletal muscle development ( 0.000473797615495446 ); GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin ( 0.000804161503941581 ); GO:0034204 lipid translocation ( 0.000804161503941581 ); GO:0045332 phospholipid translocation ( 0.000804161503941581 ); GO:0048643 positive regulation of skeletal muscle development ( 0.000804161503941581 ); GO:0008179 adenylate cyclase binding ( 0.000804161503941581 ); GO:0051380 norepinephrine binding ( 0.000804161503941581 ); GO:0014706 striated muscle development ( 0.00113887911531526 ); GO:0002024 diet induced thermogenesis ( 0.00120603002276776 ); GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure ( 0.00120603002276776 ); GO:0032091 negative regulation of protein binding ( 0.00120603002276776 ); GO:0045844 positive regulation of striated muscle development ( 0.00120603002276776 ); GO:0045986 negative regulation of smooth muscle contraction ( 0.00120603002276776 ); GO:0048630 skeletal muscle growth ( 0.00120603002276776 ); GO:0048636 positive regulation of muscle development ( 0.00120603002276776 ); GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity ( 0.00120603002276776 ); GO:0004939 beta-adrenergic receptor activity ( 0.00120603002276776 ); GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity ( 0.00160775710973693 ); GO:0021527 spinal cord association neuron differentiation ( 0.00160775710973693 ); GO:0032410 negative regulation of transporter activity ( 0.00160775710973693 ); GO:0032413 negative regulation of ion transmembrane transporter activity ( 0.00160775710973693 ); GO:0051930 regulation of sensory perception of pain ( 0.00160775710973693 ); GO:0051931 regulation of sensory perception ( 0.00160775710973693 ); GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway ( 0.00200934280751575 ); GO:0022401 adaptation of signaling pathway ( 0.00200934280751575 ); GO:0031649 heat generation ( 0.00200934280751575 ); GO:0048639 positive regulation of developmental growth ( 0.00200934280751575 ); GO:0048664 neuron fate determination ( 0.00200934280751575 ); GO:0001515 opioid peptide activity ( 0.00200934280751575 ); GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine ( 0.00241078715875964 ); GO:0040015 negative regulation of multicellular organism growth ( 0.00241078715875964 ); GO:0045932 negative regulation of muscle contraction ( 0.00241078715875964 ); GO:0050873 brown fat cell differentiation ( 0.00241078715875964 ); GO:0007517 muscle development ( 0.00249746350033168 ); GO:0008333 endosome to lysosome transport ( 0.00281209020611339 ); GO:0044253 positive regulation of multicellular organismal metabolic process ( 0.00281209020611339 ); GO:0045909 positive regulation of vasodilation ( 0.00281209020611339 ); GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity ( 0.00281209020611339 ); GO:0051926 negative regulation of calcium ion transport ( 0.00281209020611339 ); GO:0003085 negative regulation of systemic arterial blood pressure ( 0.00321325199221201 ); GO:0021516 dorsal spinal cord development ( 0.00321325199221201 ); GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway ( 0.00321325199221201 ); GO:0048638 regulation of developmental growth ( 0.00321325199221201 ); GO:0002021 response to dietary excess ( 0.00361427255967794 ); GO:0002028 regulation of sodium ion transport ( 0.00361427255967794 ); GO:0044246 regulation of multicellular organismal metabolic process ( 0.00361427255967794 ); GO:0045823 positive regulation of heart contraction ( 0.00361427255967794 ); GO:0004935 adrenoceptor activity ( 0.00361427255967794 ); GO:0030279 negative regulation of ossification ( 0.00401515195112445 ); GO:0043271 negative regulation of ion transport ( 0.00401515195112445 ); GO:0009165 nucleotide biosynthetic process ( 0.00415741773291867 ); GO:0045776 negative regulation of blood pressure ( 0.00441589020915356 ); GO:0000299 integral to membrane of membrane fraction ( 0.00441589020915356 ); GO:0001659 temperature homeostasis ( 0.0048164873763562 ); GO:0048665 neuron fate specification ( 0.0048164873763562 ); GO:0009409 response to cold ( 0.00521694349531354 ); GO:0042312 regulation of vasodilation ( 0.00521694349531354 ); GO:0046851 negative regulation of bone remodeling ( 0.00521694349531354 ); GO:0007339 binding of sperm to zona pellucida ( 0.00561725860859519 ); GO:0035036 sperm-egg recognition ( 0.00561725860859519 ); GO:0050728 negative regulation of inflammatory response ( 0.00561725860859519 ); GO:0007041 lysosomal transport ( 0.00601743275876021 ); GO:0030501 positive regulation of bone mineralization ( 0.00601743275876021 ); GO:0031348 negative regulation of defense response ( 0.00601743275876021 ); GO:0034104 negative regulation of tissue remodeling ( 0.00601743275876021 ); GO:0048641 regulation of skeletal muscle development ( 0.00601743275876021 ); GO:0004012 phospholipid-translocating ATPase activity ( 0.00601743275876021 ); GO:0015247 aminophospholipid transporter activity ( 0.00601743275876021 ); GO:0070169 positive regulation of biomineral formation ( 0.00641746598835713 ); GO:0006753 nucleoside phosphate metabolic process ( 0.0067337252262446 ); GO:0009117 nucleotide metabolic process ( 0.0067337252262446 ); GO:0001947 heart looping ( 0.00681735833992403 ); GO:0009988 cell-cell recognition ( 0.00681735833992403 ); GO:0045453 bone resorption ( 0.00681735833992403 ); GO:0021515 cell differentiation in spinal cord ( 0.00721710985598756 ); GO:0043393 regulation of protein binding ( 0.00721710985598756 ); GO:0055086 nucleobase, nucleoside and nucleotide metabolic process ( 0.00731799806300508 ); GO:0016044 membrane organization ( 0.00757530615633847 ); GO:0022898 regulation of transmembrane transporter activity ( 0.0076167205790646 ); GO:0032409 regulation of transporter activity ( 0.0076167205790646 ); GO:0032412 regulation of ion transmembrane transporter activity ( 0.0076167205790646 ); GO:0045778 positive regulation of ossification ( 0.0076167205790646 ); GO:0005184 neuropeptide hormone activity ( 0.0076167205790646 ); GO:0006940 regulation of smooth muscle contraction ( 0.00841551981626976 ); GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( 0.00841551981626976 ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( 0.00841551981626976 ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( 0.00841551981626976 ); GO:0005901 caveola ( 0.00841551981626976 ); GO:0015459 potassium channel regulator activity ( 0.00841551981626976 ); GO:0007034 vacuolar transport ( 0.00881470841537757 ); GO:0032102 negative regulation of response to external stimulus ( 0.00881470841537757 ); GO:0046852 positive regulation of bone remodeling ( 0.00881470841537757 ); GO:0030500 regulation of bone mineralization ( 0.00921375639145716 ); GO:0034105 positive regulation of tissue remodeling ( 0.00921375639145716 ); GO:0001708 cell fate specification ( 0.00961266378697145 ); GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ( 0.00961266378697145 ); GO:0045665 negative regulation of neuron differentiation ( 0.00961266378697145 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- aktpathway ( 0.00281209020611339 ); igf1rpathway ( 0.0048164873763562 ); gpcrpathway ( 0.0124010828643846 ); nfatpathway ( 0.0147856863984033 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3664 ========================= ----------------C2-------------- BIOCARTA_FEEDER_PATHWAY ( 0.00361427255967794 ); BIOCARTA_RANMS_PATHWAY ( 0.00401515195112445 ); BIOCARTA_ETC_PATHWAY ( 0.00441589020915356 ); REACTOME_CITRIC_ACID_CYCLE ( 0.0076167205790646 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_PRDX3 ( 0.000440230667437416 ); MORF_HAT1 ( 0.00165871540499915 ); MORF_HDAC1 ( 0.00340961582101358 ); module_457 ( 0.00401515195112445 ); MORF_CSNK2B ( 0.00445591561468543 ); MORF_BUB3 ( 0.00448968613310801 ); MORF_GNB1 ( 0.005190305832379 ); module_335 ( 0.00561725860859519 ); module_83 ( 0.00589999096391577 ); MORF_RAD23A ( 0.00665210797152454 ); module_392 ( 0.00721710985598756 ); ----------------C5-------------- COFACTOR_CATABOLIC_PROCESS ( 0.00401515195112445 ); NLS_BEARING_SUBSTRATE_IMPORT_INTO_NUCLEUS ( 0.0048164873763562 ); AEROBIC_RESPIRATION ( 0.00601743275876021 ); CARBOHYDRATE_KINASE_ACTIVITY ( 0.00601743275876021 ); SIGNAL_SEQUENCE_BINDING ( 0.00601743275876021 ); CELLULAR_RESPIRATION ( 0.0076167205790646 ); ----------------GOSLIM-------------- GO:0051187 cofactor catabolic process ( 0.00343936514376704 ); GO:0004454 ketohexokinase activity ( 0.00343936514376704 ); GO:0051538 3 iron, 4 sulfur cluster binding ( 0.00343936514376704 ); GO:0000072 M phase specific microtubule process ( 0.00343936514376704 ); GO:0006788 heme oxidation ( 0.00343936514376704 ); GO:0004392 heme oxygenase (decyclizing) activity ( 0.00343936514376704 ); GO:0008177 succinate dehydrogenase (ubiquinone) activity ( 0.00343936514376704 ); GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor ( 0.00343936514376704 ); GO:0051186 cofactor metabolic process ( 0.00343936514376704 ); GO:0000085 G2 phase of mitotic cell cycle ( 0.00343936514376704 ); GO:0006787 porphyrin catabolic process ( 0.00343936514376704 ); GO:0033015 tetrapyrrole catabolic process ( 0.00343936514376704 ); GO:0051319 G2 phase ( 0.00343936514376704 ); GO:0009055 electron carrier activity ( 0.00343936514376704 ); GO:0008139 nuclear localization sequence binding ( 0.00343936514376704 ); GO:0005506 iron ion binding ( 0.00343936514376704 ); GO:0006607 NLS-bearing substrate import into nucleus ( 0.00343936514376704 ); GO:0051537 2 iron, 2 sulfur cluster binding ( 0.00343936514376704 ); GO:0005048 signal sequence binding ( 0.00343936514376704 ); GO:0000018 regulation of DNA recombination ( 0.00343936514376704 ); GO:0019200 carbohydrate kinase activity ( 0.00343936514376704 ); GO:0042168 heme metabolic process ( 0.00343936514376704 ); GO:0006099 tricarboxylic acid cycle ( 0.00343936514376704 ); GO:0046356 acetyl-CoA catabolic process ( 0.00343936514376704 ); GO:0051539 4 iron, 4 sulfur cluster binding ( 0.00343936514376704 ); ----------------GO-------------- GO:0051187 cofactor catabolic process ( 6.54227561177883e-05 ); GO:0004454 ketohexokinase activity ( 0.00040215151058165 ); GO:0051538 3 iron, 4 sulfur cluster binding ( 0.00040215151058165 ); GO:0000072 M phase specific microtubule process ( 0.000804161503941581 ); GO:0006788 heme oxidation ( 0.000804161503941581 ); GO:0004392 heme oxygenase (decyclizing) activity ( 0.000804161503941581 ); GO:0008177 succinate dehydrogenase (ubiquinone) activity ( 0.000804161503941581 ); GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor ( 0.000804161503941581 ); GO:0051186 cofactor metabolic process ( 0.00176532178090029 ); GO:0000085 G2 phase of mitotic cell cycle ( 0.00200934280751575 ); GO:0006787 porphyrin catabolic process ( 0.00200934280751575 ); GO:0033015 tetrapyrrole catabolic process ( 0.00200934280751575 ); GO:0051319 G2 phase ( 0.00200934280751575 ); GO:0009055 electron carrier activity ( 0.0027595384667992 ); GO:0008139 nuclear localization sequence binding ( 0.00281209020611339 ); GO:0005506 iron ion binding ( 0.00483400790511698 ); GO:0006607 NLS-bearing substrate import into nucleus ( 0.00521694349531354 ); GO:0051537 2 iron, 2 sulfur cluster binding ( 0.00641746598835713 ); GO:0005048 signal sequence binding ( 0.00721710985598756 ); GO:0000018 regulation of DNA recombination ( 0.0076167205790646 ); GO:0019200 carbohydrate kinase activity ( 0.0076167205790646 ); GO:0042168 heme metabolic process ( 0.00801619055166014 ); GO:0006099 tricarboxylic acid cycle ( 0.00921375639145716 ); GO:0046356 acetyl-CoA catabolic process ( 0.00921375639145716 ); GO:0051539 4 iron, 4 sulfur cluster binding ( 0.00921375639145716 ); ----------------KEGG-------------- hsa00020 Citrate cycle (TCA cycle) ( 0.0124010828643846 ); hsa00860 Porphyrin and chlorophyll metabolism ( 0.0131965112222548 ); hsa00051 Fructose and mannose metabolism ( 0.0139913789540209 ); hsa05012 Parkinson's disease ( 0.0445575256792341 ); hsa00190 Oxidative phosphorylation ( 0.0449439533736001 ); ----------------CARTA-------------- mitochondriapathway ( 0.00641746598835713 ); nthipathway ( 0.00721710985598756 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3759 ========================= ----------------C2-------------- BIOCARTA_RAB_PATHWAY ( 0.0048164873763562 ); REACTOME_DUAL_INCISION_REACTION_IN_GG_NER ( 0.00801619055166014 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE ( 0.00801619055166014 ); REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_TERMINATION ( 0.00841551981626976 ); REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION ( 0.00961266378697145 ); ----------------C3-------------- ACTGCAG,MIR-17-3P ( 0.000544564087809775 ); TCANNTGAY_V$SREBP1_01 ( 0.00823656524957225 ); GTAGGCA,MIR-189 ( 0.00881470841537757 ); ----------------C4-------------- module_83 ( 0.000176263245538012 ); MORF_RAB11A ( 0.000193020124147184 ); module_159 ( 0.000440230667437416 ); MORF_PSMC2 ( 0.000659761768198904 ); module_32 ( 0.0035595926811061 ); module_114 ( 0.00657095510264563 ); module_81 ( 0.0076167205790646 ); ----------------C5-------------- EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX ( 0.00401515195112445 ); TRANS_GOLGI_NETWORK ( 0.00841551981626976 ); ----------------GOSLIM-------------- GO:0048227 plasma membrane to endosome transport ( ); GO:0008353 RNA polymerase subunit kinase activity ( ); GO:0005675 holo TFIIH complex ( ); GO:0005852 eukaryotic translation initiation factor 3 complex ( ); GO:0055038 recycling endosome membrane ( ); GO:0000315 organellar large ribosomal subunit ( ); GO:0005762 mitochondrial large ribosomal subunit ( ); GO:0019905 syntaxin binding ( ); GO:0055037 recycling endosome ( ); GO:0000718 nucleotide-excision repair, DNA damage removal ( ); GO:0000149 SNARE binding ( ); GO:0006412 translation ( ); ----------------GO-------------- GO:0048227 plasma membrane to endosome transport ( 0.000804161503941581 ); GO:0008353 RNA polymerase subunit kinase activity ( 0.00200934280751575 ); GO:0005675 holo TFIIH complex ( 0.00241078715875964 ); GO:0005852 eukaryotic translation initiation factor 3 complex ( 0.00401515195112445 ); GO:0055038 recycling endosome membrane ( 0.00401515195112445 ); GO:0000315 organellar large ribosomal subunit ( 0.00441589020915356 ); GO:0005762 mitochondrial large ribosomal subunit ( 0.00441589020915356 ); GO:0019905 syntaxin binding ( 0.00641746598835713 ); GO:0055037 recycling endosome ( 0.00721710985598756 ); GO:0000718 nucleotide-excision repair, DNA damage removal ( 0.00841551981626976 ); GO:0000149 SNARE binding ( 0.00841551981626976 ); GO:0006412 translation ( 0.00846266329276749 ); ----------------KEGG-------------- hsa03022 Basal transcription factors ( 0.0131965112222548 ); hsa03420 Nucleotide excision repair ( 0.0171652503919058 ); hsa03010 Ribosome ( 0.028595725634728 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0243342988662651 ); ----------------immu-------------- ( ); ----------------ARE-------------- ARE_C5 ( 0.00738627924237288 ); ARE_ALL ( 0.0194930816863581 ); ============================ group2013 ========================= ----------------C2-------------- ( 0.00666764511175721 ); ----------------C3-------------- ( ); ----------------C4-------------- module_83 ( 0.000111400174916273 ); MORF_JUND ( 0.000205177946076248 ); GCM_PSME1 ( 0.000314695656955393 ); GCM_APEX1 ( 0.000580442972317791 ); GCM_NPM1 ( 0.000613614916752099 ); GCM_ACTG1 ( 0.0006826700320624 ); MORF_ACP1 ( 0.0016778138379549 ); module_390 ( 0.00281209020611384 ); module_151 ( 0.00446905903432133 ); module_50 ( 0.00456620230200799 ); module_89 ( 0.00491670716035253 ); module_114 ( 0.00498012239164386 ); module_534 ( 0.0052671062272005 ); module_203 ( 0.0056173995291634 ); module_543 ( 0.0056173995291634 ); module_90 ( 0.0059675870928444 ); module_414 ( 0.0059675870928444 ); module_392 ( 0.00631766894484453 ); module_552 ( 0.00631766894484453 ); module_168 ( 0.00771693976783117 ); module_222 ( 0.00771693976783117 ); module_189 ( 0.00806649346022859 ); module_421 ( 0.00806649346022859 ); GNF2_CBFB ( 0.00911452133048107 ); module_127 ( 0.00911452133048107 ); ----------------C5-------------- ANTI_APOPTOSIS ( 0.000647691067951679 ); NEGATIVE_REGULATION_OF_APOPTOSIS ( 0.00105242280175865 ); NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH ( 0.00106706638926005 ); NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS ( 0.00182737760449181 ); MACROMOLECULAR_COMPLEX ( 0.00290727983894662 ); OLIGOSACCHARYL_TRANSFERASE_COMPLEX ( 0.00316312442127897 ); REGULATION_OF_APOPTOSIS ( 0.00545270629603915 ); REGULATION_OF_PROGRAMMED_CELL_DEATH ( 0.00548492915054463 ); REGULATION_OF_PROTEIN_STABILITY ( 0.00666764511175721 ); APOPTOSIS_GO ( 0.00862522270192727 ); PROGRAMMED_CELL_DEATH ( 0.00866512839926708 ); REGULATION_OF_DEVELOPMENTAL_PROCESS ( 0.00894685119242243 ); UBIQUITIN_LIGASE_COMPLEX ( 0.00911452133048107 ); ----------------GOSLIM-------------- GO:0032991 macromolecular complex ( 0.000629391417044095 ); GO:0006916 anti-apoptosis ( 0.000629391417044095 ); GO:0018196 peptidyl-asparagine modification ( 0.000629391417044095 ); GO:0018279 protein amino acid N-linked glycosylation via asparagine ( 0.000629391417044095 ); GO:0008250 oligosaccharyltransferase complex ( 0.000629391417044095 ); GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity ( 0.000629391417044095 ); GO:0004576 oligosaccharyl transferase activity ( 0.000629391417044095 ); GO:0043066 negative regulation of apoptosis ( 0.000629391417044095 ); GO:0043069 negative regulation of programmed cell death ( 0.000629391417044095 ); GO:0004859 phospholipase inhibitor activity ( 0.000629391417044095 ); GO:0005844 polysome ( 0.000629391417044095 ); GO:0043499 eukaryotic cell surface binding ( 0.000629391417044095 ); GO:0055102 lipase inhibitor activity ( 0.000629391417044095 ); GO:0005839 proteasome core complex ( 0.000629391417044095 ); GO:0004298 threonine-type endopeptidase activity ( 0.000629391417044095 ); GO:0070003 threonine-type peptidase activity ( 0.000629391417044095 ); GO:0005544 calcium-dependent phospholipid binding ( 0.000629391417044095 ); GO:0043498 cell surface binding ( 0.000629391417044095 ); GO:0030529 ribonucleoprotein complex ( 0.000629391417044095 ); GO:0051093 negative regulation of developmental process ( 0.000629391417044095 ); GO:0044267 cellular protein metabolic process ( 0.000629391417044095 ); GO:0001824 blastocyst development ( 0.000629391417044095 ); GO:0019538 protein metabolic process ( 0.000629391417044095 ); GO:0050819 negative regulation of coagulation ( 0.000629391417044095 ); ----------------GO-------------- GO:0032991 macromolecular complex ( 0.000268333590999038 ); GO:0006916 anti-apoptosis ( 0.00158748049925114 ); GO:0018196 peptidyl-asparagine modification ( 0.00281209020611384 ); GO:0018279 protein amino acid N-linked glycosylation via asparagine ( 0.00281209020611384 ); GO:0008250 oligosaccharyltransferase complex ( 0.00281209020611384 ); GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity ( 0.00281209020611384 ); GO:0004576 oligosaccharyl transferase activity ( 0.00316312442127897 ); GO:0043066 negative regulation of apoptosis ( 0.00349993207726248 ); GO:0043069 negative regulation of programmed cell death ( 0.00363147552215591 ); GO:0004859 phospholipase inhibitor activity ( 0.00386487510436373 ); GO:0005844 polysome ( 0.00456620230200799 ); GO:0043499 eukaryotic cell surface binding ( 0.00491670716035253 ); GO:0055102 lipase inhibitor activity ( 0.00491670716035253 ); GO:0005839 proteasome core complex ( 0.00666764511175721 ); GO:0004298 threonine-type endopeptidase activity ( 0.00701751562017117 ); GO:0070003 threonine-type peptidase activity ( 0.00701751562017117 ); GO:0005544 calcium-dependent phospholipid binding ( 0.00771693976783117 ); GO:0043498 cell surface binding ( 0.00806649346022859 ); GO:0030529 ribonucleoprotein complex ( 0.00826991307288477 ); GO:0051093 negative regulation of developmental process ( 0.00854566708827376 ); GO:0044267 cellular protein metabolic process ( 0.00864578663482751 ); GO:0001824 blastocyst development ( 0.00876528421499401 ); GO:0019538 protein metabolic process ( 0.00891460340114443 ); GO:0050819 negative regulation of coagulation ( 0.00911452133048107 ); ----------------KEGG-------------- hsa00510 N-Glycan biosynthesis ( 0.0146879889531635 ); hsa03050 Proteasome ( 0.0153827793094932 ); hsa03010 Ribosome ( 0.0250658423323008 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0407965536870063 ); hsa05322 Systemic lupus erythematosus ( 0.0435099987467595 ); ----------------CARTA-------------- nkcellspathway ( 0.00771693976783117 ); no1pathway ( 0.0136450154892503 ); ----------------RBP-------------- IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.00145871061531775 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00256434885703268 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00319956299693055 ); ELAVL1_CLIP-SEQ_(Kishore_2011) ( 0.00443981300170788 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0111239139895391 ); TIAL1_iCLIP_(Wang_2010) ( 0.0286598586403627 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0313991270014903 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2584 ========================= ----------------C2-------------- REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION ( 0.00351405271181626 ); BIOCARTA_BCELLSURVIVAL_PATHWAY ( 0.0052671062272005 ); BIOCARTA_EIF_PATHWAY ( 0.0056173995291634 ); REACTOME_DEADENYLATION_OF_MRNA ( 0.0073672804966699 ); BIOCARTA_MTOR_PATHWAY ( 0.00806649346022859 ); BIOCARTA_EIF4_PATHWAY ( 0.00841594160042891 ); ----------------C3-------------- ( ); ----------------C4-------------- MORF_EIF3S6 ( 0.000624873235258813 ); MORF_SKP1A ( 0.00158748049925114 ); MORF_AP2M1 ( 0.0019831100620413 ); MORF_HDAC1 ( 0.00257638059379259 ); MORF_DEK ( 0.00269015632239984 ); MORF_RAN ( 0.0030456085181893 ); module_185 ( 0.00316312442127897 ); MORF_CSNK2B ( 0.00337070609553378 ); MORF_RAD23A ( 0.00504196509700365 ); module_315 ( 0.0052671062272005 ); module_537 ( 0.0059675870928444 ); module_81 ( 0.00666764511175721 ); module_439 ( 0.00701751562017117 ); module_249 ( 0.0073672804966699 ); module_295 ( 0.0073672804966699 ); module_343 ( 0.00876528421499401 ); GNF2_MKI67 ( 0.00911452133048107 ); module_115 ( 0.00911452133048107 ); GNF2_H2AFX ( 0.00981267917042006 ); ----------------C5-------------- INTRACELLULAR_ORGANELLE_PART ( 0.000330970246308295 ); ORGANELLE_PART ( 0.000336590147320805 ); PROTEIN_COMPLEX ( 0.00197235786165659 ); MACROMOLECULAR_COMPLEX ( 0.00290727983894662 ); COENZYME_BIOSYNTHETIC_PROCESS ( 0.00351405271181626 ); FATTY_ACID_BETA_OXIDATION ( 0.00386487510436373 ); INTEGRATOR_COMPLEX ( 0.00456620230200799 ); G2_M_TRANSITION_OF_MITOTIC_CELL_CYCLE ( 0.00456620230200799 ); CASPASE_REGULATOR_ACTIVITY ( 0.00456620230200799 ); NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY ( 0.00491670716035253 ); SPINDLE_MICROTUBULE ( 0.0052671062272005 ); POSITIVE_REGULATION_OF_CELL_CYCLE ( 0.0056173995291634 ); ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION ( 0.0059675870928444 ); FATTY_ACID_OXIDATION ( 0.00631766894484453 ); MICROTUBULE_ORGANIZING_CENTER_PART ( 0.00666764511175721 ); CYTOKINESIS ( 0.00666764511175721 ); NUCLEAR_LUMEN ( 0.00673960601428551 ); CELL_DIVISION ( 0.0073672804966699 ); REGULATION_OF_MITOTIC_CELL_CYCLE ( 0.0073672804966699 ); COFACTOR_BIOSYNTHETIC_PROCESS ( 0.0073672804966699 ); MRNA_BINDING ( 0.00771693976783117 ); COFACTOR_BINDING ( 0.00771693976783117 ); ORGANELLE_LOCALIZATION ( 0.00841594160042891 ); CYTOPLASMIC_PART ( 0.00867146866822713 ); ORGANELLE_LUMEN ( 0.00939795437319487 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00939795437319487 ); HYDRO_LYASE_ACTIVITY ( 0.00946365297344109 ); ----------------GOSLIM-------------- GO:0070013 intracellular organelle lumen ( 0.00905713214400583 ); GO:0043233 organelle lumen ( 0.00905713214400583 ); GO:0031974 membrane-enclosed lumen ( 0.00905713214400583 ); GO:0004395 hexaprenyldihydroxybenzoate methyltransferase activity ( 0.00905713214400583 ); GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ( 0.00905713214400583 ); GO:0010420 polyprenyldihydroxybenzoate methyltransferase activity ( 0.00905713214400583 ); GO:0030580 quinone cofactor methyltransferase activity ( 0.00905713214400583 ); GO:0008169 C-methyltransferase activity ( 0.00905713214400583 ); GO:0031503 protein complex localization ( 0.00905713214400583 ); GO:0003988 acetyl-CoA C-acyltransferase activity ( 0.00905713214400583 ); GO:0005759 mitochondrial matrix ( 0.00905713214400583 ); GO:0031980 mitochondrial lumen ( 0.00905713214400583 ); GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity ( 0.00905713214400583 ); GO:0004300 enoyl-CoA hydratase activity ( 0.00905713214400583 ); GO:0000339 RNA cap binding ( 0.00905713214400583 ); GO:0008171 O-methyltransferase activity ( 0.00905713214400583 ); GO:0016281 eukaryotic translation initiation factor 4F complex ( 0.00905713214400583 ); GO:0006743 ubiquinone metabolic process ( 0.00905713214400583 ); GO:0006744 ubiquinone biosynthetic process ( 0.00905713214400583 ); GO:0042375 quinone cofactor metabolic process ( 0.00905713214400583 ); GO:0045426 quinone cofactor biosynthetic process ( 0.00905713214400583 ); GO:0016073 snRNA metabolic process ( 0.00905713214400583 ); GO:0016180 snRNA processing ( 0.00905713214400583 ); GO:0032039 integrator complex ( 0.00905713214400583 ); GO:0016408 C-acyltransferase activity ( 0.00905713214400583 ); GO:0044446 intracellular organelle part ( 0.00905713214400583 ); GO:0044422 organelle part ( 0.00905713214400583 ); GO:0031981 nuclear lumen ( 0.00905713214400583 ); GO:0006635 fatty acid beta-oxidation ( 0.00905713214400583 ); GO:0051087 chaperone binding ( 0.00905713214400583 ); GO:0006071 glycerol metabolic process ( 0.00905713214400583 ); GO:0009062 fatty acid catabolic process ( 0.00905713214400583 ); ----------------GO-------------- GO:0070013 intracellular organelle lumen ( 3.1158179416033e-05 ); GO:0043233 organelle lumen ( 3.48117499788787e-05 ); GO:0031974 membrane-enclosed lumen ( 3.86656476910787e-05 ); GO:0004395 hexaprenyldihydroxybenzoate methyltransferase activity ( 0.00035188257175911 ); GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ( 0.00035188257175911 ); GO:0010420 polyprenyldihydroxybenzoate methyltransferase activity ( 0.00035188257175911 ); GO:0030580 quinone cofactor methyltransferase activity ( 0.00035188257175911 ); GO:0008169 C-methyltransferase activity ( 0.000703659005601542 ); GO:0031503 protein complex localization ( 0.00105532932820795 ); GO:0003988 acetyl-CoA C-acyltransferase activity ( 0.00140689356625212 ); GO:0005759 mitochondrial matrix ( 0.00177056691230174 ); GO:0031980 mitochondrial lumen ( 0.00177056691230174 ); GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity ( 0.00210970389532661 ); GO:0004300 enoyl-CoA hydratase activity ( 0.00210970389532661 ); GO:0000339 RNA cap binding ( 0.00246095003967872 ); GO:0008171 O-methyltransferase activity ( 0.00246095003967872 ); GO:0016281 eukaryotic translation initiation factor 4F complex ( 0.00281209020611384 ); GO:0006743 ubiquinone metabolic process ( 0.00316312442127897 ); GO:0006744 ubiquinone biosynthetic process ( 0.00316312442127897 ); GO:0042375 quinone cofactor metabolic process ( 0.00316312442127897 ); GO:0045426 quinone cofactor biosynthetic process ( 0.00316312442127897 ); GO:0016073 snRNA metabolic process ( 0.00351405271181626 ); GO:0016180 snRNA processing ( 0.00351405271181626 ); GO:0032039 integrator complex ( 0.00386487510436373 ); GO:0016408 C-acyltransferase activity ( 0.00421559162555218 ); GO:0044446 intracellular organelle part ( 0.00439210634256454 ); GO:0044422 organelle part ( 0.00448045283848627 ); GO:0031981 nuclear lumen ( 0.00531583996324303 ); GO:0006635 fatty acid beta-oxidation ( 0.00666764511175721 ); GO:0051087 chaperone binding ( 0.00701751562017117 ); GO:0006071 glycerol metabolic process ( 0.00771693976783117 ); GO:0009062 fatty acid catabolic process ( 0.00946365297344109 ); ----------------KEGG-------------- hsa00130 Ubiquinone biosynthesis ( 0.00175835174640404 ); hsa00062 Fatty acid elongation in mitochondria ( 0.00351405271181626 ); hsa00120 Bile acid biosynthesis ( 0.0112077300292595 ); hsa00071 Fatty acid metabolism ( 0.0160771496837524 ); hsa00280 Valine, leucine and isoleucine degradation ( 0.0160771496837524 ); hsa05210 Colorectal cancer ( 0.0291906710899603 ); ----------------CARTA-------------- mcmpathway ( 0.00140689356625212 ); ionpathway ( 0.00281209020611384 ); gata3pathway ( 0.0052671062272005 ); hivnefpathway ( 0.0105104153325924 ); il2rbpathway ( 0.0146879889531635 ); ----------------RBP-------------- ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0111239139895391 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0313991270014903 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0347280333184338 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0400582084313673 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2633 ========================= ----------------C2-------------- ( 0.00456620230200799 ); ----------------C3-------------- ( ); ----------------C4-------------- module_151 ( 0.00446905903432133 ); module_114 ( 0.00498012239164386 ); GNF2_MATK ( 0.00771693976783117 ); GNF2_CDH3 ( 0.00841594160042891 ); GNF2_SERPINB5 ( 0.00876528421499401 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0006413 translational initiation ( ); GO:0022618 ribonucleoprotein complex assembly ( ); GO:0003723 RNA binding ( ); GO:0022613 ribonucleoprotein complex biogenesis ( ); GO:0005913 cell-cell adherens junction ( ); GO:0006412 translation ( ); GO:0030529 ribonucleoprotein complex ( ); GO:0019835 cytolysis ( ); GO:0034622 cellular macromolecular complex assembly ( ); ----------------GO-------------- GO:0006413 translational initiation ( 0.000211761060454096 ); GO:0022618 ribonucleoprotein complex assembly ( 0.000537622668448933 ); GO:0003723 RNA binding ( 0.00101980625771133 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.00233440593741325 ); GO:0005913 cell-cell adherens junction ( 0.0059675870928444 ); GO:0006412 translation ( 0.00642328312588736 ); GO:0030529 ribonucleoprotein complex ( 0.00826991307288477 ); GO:0019835 cytolysis ( 0.00841594160042891 ); GO:0034622 cellular macromolecular complex assembly ( 0.00862522270192727 ); ----------------KEGG-------------- hsa03010 Ribosome ( 0.0250658423323008 ); hsa04514 Cell adhesion molecules (CAMs) ( 0.0448642521813974 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0400582084313673 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2730 ========================= ----------------C2-------------- KEGG_OTHER_GLYCAN_DEGRADATION ( 0.0056173995291634 ); BIOCARTA_MITOCHONDRIA_PATHWAY ( 0.0073672804966699 ); BIOCARTA_CHEMICAL_PATHWAY ( 0.00771693976783117 ); BIOCARTA_RAS_PATHWAY ( 0.00806649346022859 ); BIOCARTA_BAD_PATHWAY ( 0.00911452133048107 ); ----------------C3-------------- ( ); ----------------C4-------------- module_537 ( 0.0059675870928444 ); GCM_BCL2L1 ( 0.00876528421499401 ); ----------------C5-------------- MITOCHONDRIAL_MEMBRANE_ORGANIZATION_AND_BIOGENESIS ( 0.00386487510436373 ); APOPTOTIC_MITOCHONDRIAL_CHANGES ( 0.00386487510436373 ); REGULATION_OF_MEMBRANE_POTENTIAL ( 0.0052671062272005 ); MITOCHONDRIAL_TRANSPORT ( 0.00701751562017117 ); ----------------GOSLIM-------------- GO:0046902 regulation of mitochondrial membrane permeability ( ); GO:0004559 alpha-mannosidase activity ( ); GO:0008634 negative regulation of survival gene product expression ( ); GO:0004176 ATP-dependent peptidase activity ( ); GO:0006510 ATP-dependent proteolysis ( ); GO:0006013 mannose metabolic process ( ); GO:0005041 low-density lipoprotein receptor activity ( ); GO:0030246 carbohydrate binding ( ); GO:0030228 lipoprotein receptor activity ( ); GO:0001502 cartilage condensation ( ); GO:0051881 regulation of mitochondrial membrane potential ( ); GO:0001836 release of cytochrome c from mitochondria ( ); GO:0015923 mannosidase activity ( ); GO:0045884 regulation of survival gene product expression ( ); GO:0030169 low-density lipoprotein binding ( ); GO:0008637 apoptotic mitochondrial changes ( ); GO:0007006 mitochondrial membrane organization ( ); GO:0008034 lipoprotein binding ( ); ----------------GO-------------- GO:0046902 regulation of mitochondrial membrane permeability ( 0.00210970389532661 ); GO:0004559 alpha-mannosidase activity ( 0.00210970389532661 ); GO:0008634 negative regulation of survival gene product expression ( 0.00246095003967872 ); GO:0004176 ATP-dependent peptidase activity ( 0.00246095003967872 ); GO:0006510 ATP-dependent proteolysis ( 0.00281209020611384 ); GO:0006013 mannose metabolic process ( 0.00316312442127897 ); GO:0005041 low-density lipoprotein receptor activity ( 0.00351405271181626 ); GO:0030246 carbohydrate binding ( 0.00379237804509815 ); GO:0030228 lipoprotein receptor activity ( 0.00386487510436373 ); GO:0001502 cartilage condensation ( 0.00456620230200799 ); GO:0051881 regulation of mitochondrial membrane potential ( 0.00456620230200799 ); GO:0001836 release of cytochrome c from mitochondria ( 0.00491670716035253 ); GO:0015923 mannosidase activity ( 0.0052671062272005 ); GO:0045884 regulation of survival gene product expression ( 0.0059675870928444 ); GO:0030169 low-density lipoprotein binding ( 0.00631766894484453 ); GO:0008637 apoptotic mitochondrial changes ( 0.00806649346022859 ); GO:0007006 mitochondrial membrane organization ( 0.00841594160042891 ); GO:0008034 lipoprotein binding ( 0.00981267917042006 ); ----------------KEGG-------------- hsa00511 N-Glycan degradation ( 0.0056173995291634 ); hsa01032 Glycan structures - degradation ( 0.010859125350851 ); hsa05014 Amyotrophic lateral sclerosis (ALS) ( 0.019196624760726 ); hsa03320 PPAR signaling pathway ( 0.0236875654342744 ); hsa05212 Pancreatic cancer ( 0.0250658423323008 ); hsa05220 Chronic myeloid leukemia ( 0.0257543551344811 ); hsa05222 Small cell lung cancer ( 0.0298766861408931 ); hsa04210 Apoptosis ( 0.0305622856350161 ); ----------------CARTA-------------- g2pathway ( 0.00946365297344109 ); p38mapkpathway ( 0.0146879889531635 ); mapkpathway ( 0.0157300169811558 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2731 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- CHAPERONE_BINDING ( 0.00421559162555218 ); G1_PHASE_OF_MITOTIC_CELL_CYCLE ( 0.00456620230200799 ); NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY ( 0.00491670716035253 ); G1_PHASE ( 0.0052671062272005 ); ----------------GOSLIM-------------- GO:0000114 regulation of transcription during G1 phase of mitotic cell cycle ( ); GO:0045210 FasL biosynthetic process ( ); GO:0001671 ATPase activator activity ( ); GO:0045109 intermediate filament organization ( ); GO:0045892 negative regulation of transcription, DNA-dependent ( ); GO:0051253 negative regulation of RNA metabolic process ( ); GO:0043154 negative regulation of caspase activity ( ); GO:0010466 negative regulation of peptidase activity ( ); GO:0000080 G1 phase of mitotic cell cycle ( ); GO:0045104 intermediate filament cytoskeleton organization ( ); GO:0016481 negative regulation of transcription ( ); GO:0051318 G1 phase ( ); GO:0045103 intermediate filament-based process ( ); GO:0010629 negative regulation of gene expression ( ); GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( ); GO:0051087 chaperone binding ( ); GO:0010558 negative regulation of macromolecule biosynthetic process ( ); GO:0031327 negative regulation of cellular biosynthetic process ( ); GO:0009890 negative regulation of biosynthetic process ( ); ----------------GO-------------- GO:0000114 regulation of transcription during G1 phase of mitotic cell cycle ( 0.00035188257175911 ); GO:0045210 FasL biosynthetic process ( 0.00035188257175911 ); GO:0001671 ATPase activator activity ( 0.00140689356625212 ); GO:0045109 intermediate filament organization ( 0.00281209020611384 ); GO:0045892 negative regulation of transcription, DNA-dependent ( 0.00309459678763218 ); GO:0051253 negative regulation of RNA metabolic process ( 0.00321870264592091 ); GO:0043154 negative regulation of caspase activity ( 0.00351405271181626 ); GO:0010466 negative regulation of peptidase activity ( 0.00456620230200799 ); GO:0000080 G1 phase of mitotic cell cycle ( 0.00491670716035253 ); GO:0045104 intermediate filament cytoskeleton organization ( 0.0052671062272005 ); GO:0016481 negative regulation of transcription ( 0.00548492915054463 ); GO:0051318 G1 phase ( 0.0056173995291634 ); GO:0045103 intermediate filament-based process ( 0.0059675870928444 ); GO:0010629 negative regulation of gene expression ( 0.00618218264193962 ); GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00691840952213503 ); GO:0051087 chaperone binding ( 0.00701751562017117 ); GO:0010558 negative regulation of macromolecule biosynthetic process ( 0.00750522989685887 ); GO:0031327 negative regulation of cellular biosynthetic process ( 0.00788326452601711 ); GO:0009890 negative regulation of biosynthetic process ( 0.00803689291769948 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2762 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00981267917042006 ); ----------------GOSLIM-------------- GO:0004986 delta-opioid receptor activity ( ); GO:0001503 ossification ( ); GO:0060348 bone development ( ); GO:0030345 structural constituent of tooth enamel ( ); GO:0030021 extracellular matrix structural constituent conferring compression resistance ( ); GO:0004985 opioid receptor activity ( ); GO:0045668 negative regulation of osteoblast differentiation ( ); GO:0001501 skeletal system development ( ); GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling ( ); GO:0045667 regulation of osteoblast differentiation ( ); ----------------GO-------------- GO:0004986 delta-opioid receptor activity ( 0.00035188257175911 ); GO:0001503 ossification ( 0.000718550416505297 ); GO:0060348 bone development ( 0.000730710619773211 ); GO:0030345 structural constituent of tooth enamel ( 0.00140689356625212 ); GO:0030021 extracellular matrix structural constituent conferring compression resistance ( 0.00175835174640404 ); GO:0004985 opioid receptor activity ( 0.00281209020611384 ); GO:0045668 negative regulation of osteoblast differentiation ( 0.00316312442127897 ); GO:0001501 skeletal system development ( 0.00357858044260411 ); GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling ( 0.00631766894484453 ); GO:0045667 regulation of osteoblast differentiation ( 0.00946365297344109 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2978 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_TTN ( 0.00911452133048107 ); module_202 ( 0.00981267917042006 ); ----------------C5-------------- LYSOSOMAL_TRANSPORT ( 0.00351405271181626 ); BILE_ACID_METABOLIC_PROCESS ( 0.00386487510436373 ); VACUOLAR_TRANSPORT ( 0.00456620230200799 ); SARCOMERE ( 0.00491670716035253 ); LIPID_HOMEOSTASIS ( 0.0056173995291634 ); MYOFIBRIL ( 0.00666764511175721 ); CONTRACTILE_FIBER_PART ( 0.00806649346022859 ); CONTRACTILE_FIBER ( 0.00876528421499401 ); LIPID_TRANSPORTER_ACTIVITY ( 0.00946365297344109 ); ----------------GOSLIM-------------- GO:0010507 negative regulation of autophagy ( ); GO:0016242 negative regulation of macroautophagy ( ); GO:0016241 regulation of macroautophagy ( ); GO:0007525 somatic muscle development ( ); GO:0010506 regulation of autophagy ( ); GO:0032105 negative regulation of response to extracellular stimulus ( ); GO:0032108 negative regulation of response to nutrient levels ( ); GO:0046686 response to cadmium ion ( ); GO:0031330 negative regulation of cellular catabolic process ( ); GO:0032104 regulation of response to extracellular stimulus ( ); GO:0032107 regulation of response to nutrient levels ( ); GO:0008158 hedgehog receptor activity ( ); GO:0016236 macroautophagy ( ); GO:0015248 sterol transporter activity ( ); GO:0033344 cholesterol efflux ( ); GO:0009895 negative regulation of catabolic process ( ); GO:0005737 cytoplasm ( ); GO:0009267 cellular response to starvation ( ); GO:0032102 negative regulation of response to external stimulus ( ); GO:0031329 regulation of cellular catabolic process ( ); GO:0030018 Z disc ( ); GO:0042594 response to starvation ( ); GO:0006914 autophagy ( ); GO:0031669 cellular response to nutrient levels ( ); ----------------GO-------------- GO:0010507 negative regulation of autophagy ( 0.00035188257175911 ); GO:0016242 negative regulation of macroautophagy ( 0.00035188257175911 ); GO:0016241 regulation of macroautophagy ( 0.000703659005601542 ); GO:0007525 somatic muscle development ( 0.00105532932820795 ); GO:0010506 regulation of autophagy ( 0.00105532932820795 ); GO:0032105 negative regulation of response to extracellular stimulus ( 0.00105532932820795 ); GO:0032108 negative regulation of response to nutrient levels ( 0.00105532932820795 ); GO:0046686 response to cadmium ion ( 0.00175835174640404 ); GO:0031330 negative regulation of cellular catabolic process ( 0.00246095003967872 ); GO:0032104 regulation of response to extracellular stimulus ( 0.00246095003967872 ); GO:0032107 regulation of response to nutrient levels ( 0.00246095003967872 ); GO:0008158 hedgehog receptor activity ( 0.00316312442127897 ); GO:0016236 macroautophagy ( 0.00386487510436373 ); GO:0015248 sterol transporter activity ( 0.00421559162555218 ); GO:0033344 cholesterol efflux ( 0.00456620230200799 ); GO:0009895 negative regulation of catabolic process ( 0.00666764511175721 ); GO:0005737 cytoplasm ( 0.00750460850916974 ); GO:0009267 cellular response to starvation ( 0.00771693976783117 ); GO:0032102 negative regulation of response to external stimulus ( 0.00771693976783117 ); GO:0031329 regulation of cellular catabolic process ( 0.00876528421499401 ); GO:0030018 Z disc ( 0.00876528421499401 ); GO:0042594 response to starvation ( 0.00946365297344109 ); GO:0006914 autophagy ( 0.00981267917042006 ); GO:0031669 cellular response to nutrient levels ( 0.00981267917042006 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2998 ========================= ----------------C2-------------- ( 0.00673960601428551 ); ----------------C3-------------- ( 0.00155202610512475 ); ----------------C4-------------- ( 0.00491670716035253 ); ----------------C5-------------- ADENYLATE_CYCLASE_ACTIVATION ( 0.00631766894484453 ); G_PROTEIN_SIGNALING__ADENYLATE_CYCLASE_ACTIVATING_PATHWAY ( 0.00841594160042891 ); ----------------GOSLIM-------------- GO:0019307 mannose biosynthetic process ( 0.00873507306864386 ); GO:0048539 bone marrow development ( 0.00873507306864386 ); GO:0004615 phosphomannomutase activity ( 0.00873507306864386 ); GO:0004967 glucagon receptor activity ( 0.00873507306864386 ); GO:0017145 stem cell division ( 0.00873507306864386 ); GO:0048103 somatic stem cell division ( 0.00873507306864386 ); GO:0002011 morphogenesis of an epithelial sheet ( 0.00873507306864386 ); GO:0060216 definitive hemopoiesis ( 0.00873507306864386 ); GO:0006013 mannose metabolic process ( 0.00873507306864386 ); GO:0044249 cellular biosynthetic process ( 0.00873507306864386 ); GO:0009058 biosynthetic process ( 0.00873507306864386 ); GO:0016868 intramolecular transferase activity, phosphotransferases ( 0.00873507306864386 ); GO:0048536 spleen development ( 0.00873507306864386 ); GO:0016866 intramolecular transferase activity ( 0.00873507306864386 ); GO:0019319 hexose biosynthetic process ( 0.00873507306864386 ); ----------------GO-------------- GO:0019307 mannose biosynthetic process ( 0.000703659005601542 ); GO:0048539 bone marrow development ( 0.000703659005601542 ); GO:0004615 phosphomannomutase activity ( 0.000703659005601542 ); GO:0004967 glucagon receptor activity ( 0.000703659005601542 ); GO:0017145 stem cell division ( 0.00140689356625212 ); GO:0048103 somatic stem cell division ( 0.00140689356625212 ); GO:0002011 morphogenesis of an epithelial sheet ( 0.00175835174640404 ); GO:0060216 definitive hemopoiesis ( 0.00175835174640404 ); GO:0006013 mannose metabolic process ( 0.00316312442127897 ); GO:0044249 cellular biosynthetic process ( 0.00349662029481275 ); GO:0009058 biosynthetic process ( 0.00384273872634355 ); GO:0016868 intramolecular transferase activity, phosphotransferases ( 0.00386487510436373 ); GO:0048536 spleen development ( 0.0056173995291634 ); GO:0016866 intramolecular transferase activity ( 0.00876528421499401 ); GO:0019319 hexose biosynthetic process ( 0.00946365297344109 ); ----------------KEGG-------------- hsa00051 Fructose and mannose metabolism ( 0.0122529122905473 ); hsa03010 Ribosome ( 0.0250658423323008 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3010 ========================= ----------------C2-------------- ( 0.00351405271181626 ); ----------------C3-------------- V$MEF2_03 ( 0.00171462505301568 ); V$HAND1E47_01 ( 0.0019831100620413 ); ----------------C4-------------- module_514 ( 0.00351405271181626 ); module_44 ( 0.00494933625107512 ); module_2 ( 0.00681086492164809 ); module_373 ( 0.00771693976783117 ); module_6 ( 0.0078450726577394 ); module_5 ( 0.00854566708827376 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0002358 B cell homeostatic proliferation ( ); GO:0002360 T cell lineage commitment ( ); GO:0002326 B cell lineage commitment ( ); GO:0004024 alcohol dehydrogenase activity, zinc-dependent ( ); GO:0046622 positive regulation of organ growth ( ); GO:0033151 V(D)J recombination ( ); GO:0004022 alcohol dehydrogenase activity ( ); GO:0046620 regulation of organ growth ( ); GO:0035265 organ growth ( ); GO:0042100 B cell proliferation ( ); GO:0033077 T cell differentiation in the thymus ( ); GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus ( ); GO:0016444 somatic cell DNA recombination ( ); GO:0002200 somatic diversification of immune receptors ( ); GO:0030018 Z disc ( ); GO:0003823 antigen binding ( ); ----------------GO-------------- GO:0002358 B cell homeostatic proliferation ( 0.00035188257175911 ); GO:0002360 T cell lineage commitment ( 0.00105532932820795 ); GO:0002326 B cell lineage commitment ( 0.00140689356625212 ); GO:0004024 alcohol dehydrogenase activity, zinc-dependent ( 0.00175835174640404 ); GO:0046622 positive regulation of organ growth ( 0.00210970389532661 ); GO:0033151 V(D)J recombination ( 0.00246095003967872 ); GO:0004022 alcohol dehydrogenase activity ( 0.00281209020611384 ); GO:0046620 regulation of organ growth ( 0.00491670716035253 ); GO:0035265 organ growth ( 0.00631766894484453 ); GO:0042100 B cell proliferation ( 0.0073672804966699 ); GO:0033077 T cell differentiation in the thymus ( 0.00771693976783117 ); GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus ( 0.00806649346022859 ); GO:0016444 somatic cell DNA recombination ( 0.00806649346022859 ); GO:0002200 somatic diversification of immune receptors ( 0.00841594160042891 ); GO:0030018 Z disc ( 0.00876528421499401 ); GO:0003823 antigen binding ( 0.00911452133048107 ); ----------------KEGG-------------- hsa00624 1- and 2-Methylnaphthalene degradation ( 0.00421559162555218 ); hsa00641 3-Chloroacrylic acid degradation ( 0.00491670716035253 ); hsa00120 Bile acid biosynthesis ( 0.0112077300292595 ); hsa05340 Primary immunodeficiency ( 0.0122529122905473 ); hsa00350 Tyrosine metabolism ( 0.0157300169811558 ); hsa00071 Fatty acid metabolism ( 0.0160771496837524 ); hsa00830 Retinol metabolism ( 0.0195427092262304 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.0216170186947268 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0216170186947268 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0223076187411271 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3011 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- LIPID_TRANSPORTER_ACTIVITY ( 0.00946365297344109 ); LIPID_TRANSPORT ( 0.00981267917042006 ); ----------------GOSLIM-------------- GO:0015132 prostaglandin transmembrane transporter activity ( ); GO:0015732 prostaglandin transport ( ); GO:0015718 monocarboxylic acid transport ( ); GO:0008028 monocarboxylic acid transmembrane transporter activity ( ); ----------------GO-------------- GO:0015132 prostaglandin transmembrane transporter activity ( 0.00035188257175911 ); GO:0015732 prostaglandin transport ( 0.00105532932820795 ); GO:0015718 monocarboxylic acid transport ( 0.00631766894484453 ); GO:0008028 monocarboxylic acid transmembrane transporter activity ( 0.00701751562017117 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3019 ========================= ----------------C2-------------- BIOCARTA_IL22BP_PATHWAY ( 0.0056173995291634 ); BIOCARTA_IL10_PATHWAY ( 0.0059675870928444 ); BIOCARTA_IL6_PATHWAY ( 0.00771693976783117 ); BIOCARTA_HER2_PATHWAY ( 0.00771693976783117 ); REACTOME_METAL_ION_SLC_TRANSPORTERS ( 0.00806649346022859 ); BIOCARTA_TPO_PATHWAY ( 0.00841594160042891 ); BIOCARTA_ERK_PATHWAY ( 0.00981267917042006 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER ( 0.00409597509650788 ); ANDROGEN_RECEPTOR_SIGNALING_PATHWAY ( 0.00421559162555218 ); TRANSCRIPTION_FACTOR_BINDING ( 0.00449839605067205 ); RNA_POLYMERASE_II_TRANSCRIPTION_MEDIATOR_ACTIVITY ( 0.00456620230200799 ); THYROID_HORMONE_RECEPTOR_BINDING ( 0.0056173995291634 ); MEDIATOR_COMPLEX ( 0.00631766894484453 ); STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY ( 0.00701751562017117 ); INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY ( 0.0073672804966699 ); NUCLEAR_HORMONE_RECEPTOR_BINDING ( 0.00946365297344109 ); HORMONE_RECEPTOR_BINDING ( 0.00981267917042006 ); TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER ( 0.0098592646084027 ); ----------------GOSLIM-------------- GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway ( 0.00337070609553378 ); GO:0070102 interleukin-6-mediated signaling pathway ( 0.00403994915663453 ); GO:0005062 hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity ( 0.00491670716035253 ); GO:0060396 growth hormone receptor signaling pathway ( 0.00337070609553378 ); GO:0060416 response to growth hormone stimulus ( 0.00403994915663453 ); GO:0032355 response to estradiol stimulus ( 0.00491670716035253 ); GO:0032870 cellular response to hormone stimulus ( 0.00337070609553378 ); GO:0016455 RNA polymerase II transcription mediator activity ( 0.00403994915663453 ); GO:0042809 vitamin D receptor binding ( 0.00491670716035253 ); GO:0000119 mediator complex ( 0.00337070609553378 ); GO:0008134 transcription factor binding ( 0.00403994915663453 ); GO:0046966 thyroid hormone receptor binding ( 0.00491670716035253 ); GO:0006826 iron ion transport ( 0.00337070609553378 ); GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity ( 0.00403994915663453 ); ----------------GO-------------- GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway ( 0.000703659005601542 ); GO:0070102 interleukin-6-mediated signaling pathway ( 0.000703659005601542 ); GO:0005062 hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity ( 0.00140689356625212 ); GO:0060396 growth hormone receptor signaling pathway ( 0.00246095003967872 ); GO:0060416 response to growth hormone stimulus ( 0.00246095003967872 ); GO:0032355 response to estradiol stimulus ( 0.00316312442127897 ); GO:0032870 cellular response to hormone stimulus ( 0.0052671062272005 ); GO:0016455 RNA polymerase II transcription mediator activity ( 0.0056173995291634 ); GO:0042809 vitamin D receptor binding ( 0.00631766894484453 ); GO:0000119 mediator complex ( 0.00841594160042891 ); GO:0008134 transcription factor binding ( 0.00862522270192727 ); GO:0046966 thyroid hormone receptor binding ( 0.00876528421499401 ); GO:0006826 iron ion transport ( 0.00911452133048107 ); GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity ( 0.00946365297344109 ); ----------------KEGG-------------- hsa05221 Acute myeloid leukemia ( 0.0195427092262304 ); hsa04920 Adipocytokine signaling pathway ( 0.0229978009174007 ); hsa05212 Pancreatic cancer ( 0.0250658423323008 ); ----------------CARTA-------------- pgc1apathway ( 0.00841594160042891 ); ptenpathway ( 0.00911452133048107 ); mapkpathway ( 0.0157300169811558 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0110344563714732 ); ----------------ARE-------------- ARE_C2 ( 0.010859125350851 ); ARE_ALL ( 0.0129225239401495 ); ============================ group3052 ========================= ----------------C2-------------- ( 0.00456620230200799 ); ----------------C3-------------- ( 0.00138059084757662 ); ----------------C4-------------- module_212 ( 0.00498012239164386 ); module_519 ( 0.0052671062272005 ); module_330 ( 0.00981267917042006 ); ----------------C5-------------- ENDOPLASMIC_RETICULUM_LUMEN ( 0.00421559162555218 ); PHOSPHOLIPID_TRANSPORTER_ACTIVITY ( 0.00421559162555218 ); LIPID_TRANSPORTER_ACTIVITY ( 0.00946365297344109 ); ----------------GOSLIM-------------- GO:0001921 positive regulation of receptor recycling ( ); GO:0034959 endothelin maturation ( ); GO:0031302 intrinsic to endosome membrane ( ); GO:0033093 Weibel-Palade body ( ); GO:0008525 phosphatidylcholine transmembrane transporter activity ( ); GO:0045116 protein neddylation ( ); GO:0001919 regulation of receptor recycling ( ); GO:0001881 receptor recycling ( ); GO:0002002 regulation of angiotensin levels in blood ( ); GO:0003100 regulation of systemic arterial blood pressure by endothelin ( ); GO:0060177 regulation of angiotensin metabolic process ( ); GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway ( ); GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin ( ); GO:0042447 hormone catabolic process ( ); GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin ( ); GO:0003756 protein disulfide isomerase activity ( ); GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds ( ); GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups ( ); GO:0016486 peptide hormone processing ( ); GO:0042733 embryonic digit morphogenesis ( ); GO:0017046 peptide hormone binding ( ); GO:0030530 heterogeneous nuclear ribonucleoprotein complex ( ); GO:0001990 regulation of systemic arterial blood pressure by hormone ( ); GO:0019229 regulation of vasoconstriction ( ); GO:0050886 endocrine process ( ); GO:0051605 protein maturation via proteolysis ( ); GO:0044424 intracellular part ( ); GO:0016023 cytoplasmic membrane-bounded vesicle ( ); GO:0031988 membrane-bounded vesicle ( ); GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ( ); GO:0042310 vasoconstriction ( ); GO:0005622 intracellular ( ); GO:0031323 regulation of cellular metabolic process ( ); GO:0060255 regulation of macromolecule metabolic process ( ); GO:0005515 protein binding ( ); GO:0043112 receptor metabolic process ( ); GO:0042562 hormone binding ( ); ----------------GO-------------- GO:0001921 positive regulation of receptor recycling ( 0.00035188257175911 ); GO:0034959 endothelin maturation ( 0.00035188257175911 ); GO:0031302 intrinsic to endosome membrane ( 0.00035188257175911 ); GO:0033093 Weibel-Palade body ( 0.000703659005601542 ); GO:0008525 phosphatidylcholine transmembrane transporter activity ( 0.000703659005601542 ); GO:0045116 protein neddylation ( 0.00105532932820795 ); GO:0001919 regulation of receptor recycling ( 0.00140689356625212 ); GO:0001881 receptor recycling ( 0.00175835174640404 ); GO:0002002 regulation of angiotensin levels in blood ( 0.00175835174640404 ); GO:0003100 regulation of systemic arterial blood pressure by endothelin ( 0.00175835174640404 ); GO:0060177 regulation of angiotensin metabolic process ( 0.00175835174640404 ); GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway ( 0.00210970389532661 ); GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin ( 0.00281209020611384 ); GO:0042447 hormone catabolic process ( 0.00281209020611384 ); GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin ( 0.00316312442127897 ); GO:0003756 protein disulfide isomerase activity ( 0.00316312442127897 ); GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds ( 0.00316312442127897 ); GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups ( 0.00351405271181626 ); GO:0016486 peptide hormone processing ( 0.00491670716035253 ); GO:0042733 embryonic digit morphogenesis ( 0.00491670716035253 ); GO:0017046 peptide hormone binding ( 0.0052671062272005 ); GO:0030530 heterogeneous nuclear ribonucleoprotein complex ( 0.0056173995291634 ); GO:0001990 regulation of systemic arterial blood pressure by hormone ( 0.0059675870928444 ); GO:0019229 regulation of vasoconstriction ( 0.0059675870928444 ); GO:0050886 endocrine process ( 0.0059675870928444 ); GO:0051605 protein maturation via proteolysis ( 0.00701751562017117 ); GO:0044424 intracellular part ( 0.00711490428931672 ); GO:0016023 cytoplasmic membrane-bounded vesicle ( 0.00807551500934966 ); GO:0031988 membrane-bounded vesicle ( 0.00830904987694093 ); GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ( 0.00841594160042891 ); GO:0042310 vasoconstriction ( 0.00876528421499401 ); GO:0005622 intracellular ( 0.00954063528864664 ); GO:0031323 regulation of cellular metabolic process ( 0.00969304333598891 ); GO:0060255 regulation of macromolecule metabolic process ( 0.00975577143933239 ); GO:0005515 protein binding ( 0.0097903237650084 ); GO:0043112 receptor metabolic process ( 0.00981267917042006 ); GO:0042562 hormone binding ( 0.00981267917042006 ); ----------------KEGG-------------- ( 0.0202345641482173 ); ----------------CARTA-------------- ( 0.0052671062272005 ); ----------------RBP-------------- AGO2-MNASE_PAR-CLIP_(Kishore_2011) ( 0.000652175839573101 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.00219428063625371 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.00256434885703268 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.00319956299693055 ); ELAVL1_CLIP-SEQ_(Kishore_2011) ( 0.00443981300170788 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.00500176232697693 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.0111239139895391 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0138620247160468 ); TIAL1_iCLIP_(Wang_2010) ( 0.0286598586403627 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3066 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_CDKN1C ( 0.00946365297344109 ); module_29 ( 0.00981267917042006 ); ----------------C5-------------- REPRODUCTIVE_PROCESS ( 0.00126639335706982 ); REPRODUCTION ( 0.00334513953687553 ); NEUROPEPTIDE_HORMONE_ACTIVITY ( 0.00386487510436373 ); LEARNING_AND_OR_MEMORY ( 0.00491670716035253 ); MICROTUBULE_MOTOR_ACTIVITY ( 0.0056173995291634 ); CELL_PROJECTION_PART ( 0.00666764511175721 ); MOTOR_ACTIVITY ( 0.00981267917042006 ); ----------------GOSLIM-------------- GO:0010840 regulation of circadian sleep/wake cycle, wakefulness ( 0.00365578985601685 ); GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness ( 0.00365578985601685 ); GO:0042746 circadian sleep/wake cycle, wakefulness ( 0.00365578985601685 ); GO:0042321 negative regulation of circadian sleep/wake cycle, sleep ( 0.00365578985601685 ); GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep ( 0.00365578985601685 ); GO:0042754 negative regulation of circadian rhythm ( 0.00365578985601685 ); GO:0043400 cortisol secretion ( 0.00365578985601685 ); GO:0048521 negative regulation of behavior ( 0.00365578985601685 ); GO:0051462 regulation of cortisol secretion ( 0.00365578985601685 ); GO:0051464 positive regulation of cortisol secretion ( 0.00365578985601685 ); GO:0042320 regulation of circadian sleep/wake cycle, REM sleep ( 0.00365578985601685 ); GO:0042747 circadian sleep/wake cycle, REM sleep ( 0.00365578985601685 ); GO:0042753 positive regulation of circadian rhythm ( 0.00365578985601685 ); GO:0022410 circadian sleep/wake cycle process ( 0.00365578985601685 ); GO:0042749 regulation of circadian sleep/wake cycle ( 0.00365578985601685 ); GO:0045187 regulation of circadian sleep/wake cycle, sleep ( 0.00365578985601685 ); GO:0050802 circadian sleep/wake cycle, sleep ( 0.00365578985601685 ); GO:0042745 circadian sleep/wake cycle ( 0.00365578985601685 ); GO:0006704 glucocorticoid biosynthetic process ( 0.00365578985601685 ); GO:0007567 parturition ( 0.00365578985601685 ); GO:0030325 adrenal gland development ( 0.00365578985601685 ); GO:0048512 circadian behavior ( 0.00365578985601685 ); GO:0007622 rhythmic behavior ( 0.00365578985601685 ); GO:0030431 sleep ( 0.00365578985601685 ); GO:0005858 axonemal dynein complex ( 0.00365578985601685 ); GO:0042752 regulation of circadian rhythm ( 0.00365578985601685 ); GO:0008211 glucocorticoid metabolic process ( 0.00365578985601685 ); GO:0044447 axoneme part ( 0.00365578985601685 ); GO:0005930 axoneme ( 0.00365578985601685 ); GO:0046887 positive regulation of hormone secretion ( 0.00365578985601685 ); GO:0005184 neuropeptide hormone activity ( 0.00365578985601685 ); GO:0048520 positive regulation of behavior ( 0.00365578985601685 ); GO:0050795 regulation of behavior ( 0.00365578985601685 ); ----------------GO-------------- GO:0010840 regulation of circadian sleep/wake cycle, wakefulness ( 0.00035188257175911 ); GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness ( 0.00035188257175911 ); GO:0042746 circadian sleep/wake cycle, wakefulness ( 0.00035188257175911 ); GO:0042321 negative regulation of circadian sleep/wake cycle, sleep ( 0.000703659005601542 ); GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep ( 0.000703659005601542 ); GO:0042754 negative regulation of circadian rhythm ( 0.000703659005601542 ); GO:0043400 cortisol secretion ( 0.000703659005601542 ); GO:0048521 negative regulation of behavior ( 0.000703659005601542 ); GO:0051462 regulation of cortisol secretion ( 0.000703659005601542 ); GO:0051464 positive regulation of cortisol secretion ( 0.000703659005601542 ); GO:0042320 regulation of circadian sleep/wake cycle, REM sleep ( 0.00105532932820795 ); GO:0042747 circadian sleep/wake cycle, REM sleep ( 0.00105532932820795 ); GO:0042753 positive regulation of circadian rhythm ( 0.00105532932820795 ); GO:0022410 circadian sleep/wake cycle process ( 0.00140689356625212 ); GO:0042749 regulation of circadian sleep/wake cycle ( 0.00140689356625212 ); GO:0045187 regulation of circadian sleep/wake cycle, sleep ( 0.00140689356625212 ); GO:0050802 circadian sleep/wake cycle, sleep ( 0.00140689356625212 ); GO:0042745 circadian sleep/wake cycle ( 0.00175835174640404 ); GO:0006704 glucocorticoid biosynthetic process ( 0.00210970389532661 ); GO:0007567 parturition ( 0.00210970389532661 ); GO:0030325 adrenal gland development ( 0.00210970389532661 ); GO:0048512 circadian behavior ( 0.00210970389532661 ); GO:0007622 rhythmic behavior ( 0.00281209020611384 ); GO:0030431 sleep ( 0.00316312442127897 ); GO:0005858 axonemal dynein complex ( 0.00316312442127897 ); GO:0042752 regulation of circadian rhythm ( 0.00351405271181626 ); GO:0008211 glucocorticoid metabolic process ( 0.00386487510436373 ); GO:0044447 axoneme part ( 0.00386487510436373 ); GO:0005930 axoneme ( 0.0056173995291634 ); GO:0046887 positive regulation of hormone secretion ( 0.0059675870928444 ); GO:0005184 neuropeptide hormone activity ( 0.00666764511175721 ); GO:0048520 positive regulation of behavior ( 0.00771693976783117 ); GO:0050795 regulation of behavior ( 0.00806649346022859 ); ----------------KEGG-------------- hsa03010 Ribosome ( 0.0250658423323008 ); hsa04730 Long-term depression ( 0.0257543551344811 ); hsa05322 Systemic lupus erythematosus ( 0.0435099987467595 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3068 ========================= ----------------C2-------------- BIOCARTA_ECM_PATHWAY ( 0.00806649346022859 ); REACTOME_FURTHER_PLATELET_RELEASATE ( 0.00806649346022859 ); ----------------C3-------------- ( 0.00421559162555218 ); ----------------C4-------------- GNF2_MSN ( 0.00841594160042891 ); GCM_MSN ( 0.00876528421499401 ); ----------------C5-------------- ( 0.0056173995291634 ); ----------------GOSLIM-------------- GO:0016337 cell-cell adhesion ( ); GO:0001843 neural tube closure ( ); GO:0014020 primary neural tube formation ( ); GO:0001841 neural tube formation ( ); GO:0001838 embryonic epithelial tube formation ( ); GO:0050839 cell adhesion molecule binding ( ); ----------------GO-------------- GO:0016337 cell-cell adhesion ( 0.0024429714555751 ); GO:0001843 neural tube closure ( 0.00421559162555218 ); GO:0014020 primary neural tube formation ( 0.00491670716035253 ); GO:0001841 neural tube formation ( 0.00666764511175721 ); GO:0001838 embryonic epithelial tube formation ( 0.00701751562017117 ); GO:0050839 cell adhesion molecule binding ( 0.00841594160042891 ); ----------------KEGG-------------- hsa04520 Adherens junction ( 0.0260984552159211 ); hsa04514 Cell adhesion molecules (CAMs) ( 0.0448642521813974 ); ----------------CARTA-------------- arfpathway ( 0.00246095003967872 ); p53pathway ( 0.00281209020611384 ); p53hypoxiapathway ( 0.00386487510436373 ); her2pathway ( 0.0073672804966699 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3097 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$YY1_Q6 ( 0.00138059084757662 ); GCCATNTTG_V$YY1_Q6 ( 0.00432373968355045 ); ----------------C4-------------- module_53 ( 0.00743066079975949 ); module_52 ( 0.00834827230161338 ); module_18 ( 0.00923273260484054 ); ----------------C5-------------- NUCLEOPLASM ( 0.00363147552215591 ); TRANSCRIPTION_FACTOR_TFIID_COMPLEX ( 0.00491670716035253 ); NUCLEAR_LUMEN ( 0.00673960601428551 ); ORGANELLE_LUMEN ( 0.00939795437319487 ); MEMBRANE_ENCLOSED_LUMEN ( 0.00939795437319487 ); ----------------GOSLIM-------------- GO:0005673 transcription factor TFIIE complex ( 0.00718492476932715 ); GO:0016986 transcription initiation factor activity ( 0.00718492476932715 ); GO:0005669 transcription factor TFIID complex ( 0.00718492476932715 ); ----------------GO-------------- GO:0005673 transcription factor TFIIE complex ( 0.00105532932820795 ); GO:0016986 transcription initiation factor activity ( 0.00140689356625212 ); GO:0005669 transcription factor TFIID complex ( 0.00701751562017117 ); ----------------KEGG-------------- ( 0.0115562293943366 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0356167680185723 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3122 ========================= ----------------C2-------------- REACTOME_PYRIMIDINE_CATABOLISM ( 0.00351405271181626 ); KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM ( 0.00771693976783117 ); REACTOME_PYRIMIDINE_METABOLISM ( 0.00771693976783117 ); ----------------C3-------------- ( ); ----------------C4-------------- module_237 ( 0.000128976796130054 ); module_547 ( 0.00491670716035253 ); module_313 ( 0.0056173995291634 ); module_240 ( 0.0059675870928444 ); module_156 ( 0.00631766894484453 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0008665 2'-phosphotransferase activity ( ); GO:0017150 tRNA dihydrouridine synthase activity ( ); GO:0006213 pyrimidine nucleoside metabolic process ( ); GO:0008253 5'-nucleotidase activity ( ); GO:0008252 nucleotidase activity ( ); GO:0051539 4 iron, 4 sulfur cluster binding ( ); ----------------GO-------------- GO:0008665 2'-phosphotransferase activity ( 0.000703659005601542 ); GO:0017150 tRNA dihydrouridine synthase activity ( 0.00140689356625212 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.00281209020611384 ); GO:0008253 5'-nucleotidase activity ( 0.00281209020611384 ); GO:0008252 nucleotidase activity ( 0.00351405271181626 ); GO:0051539 4 iron, 4 sulfur cluster binding ( 0.00806649346022859 ); ----------------KEGG-------------- hsa00760 Nicotinate and nicotinamide metabolism ( 0.00841594160042891 ); hsa00240 Pyrimidine metabolism ( 0.0315899061660799 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0136391130033434 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3127 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_99 ( 0.00577895133643972 ); GCM_ERCC4 ( 0.00981267917042006 ); ----------------C5-------------- SUPEROXIDE_METABOLIC_PROCESS ( 0.00281209020611384 ); RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY ( 0.00386487510436373 ); ACTIN_FILAMENT_POLYMERIZATION ( 0.00491670716035253 ); RHO_GTPASE_ACTIVATOR_ACTIVITY ( 0.0056173995291634 ); PROTEIN_POLYMERIZATION ( 0.00631766894484453 ); OXYGEN_AND_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS ( 0.00631766894484453 ); RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY ( 0.00631766894484453 ); ACTIN_POLYMERIZATION_AND_OR_DEPOLYMERIZATION ( 0.00806649346022859 ); RAS_GTPASE_ACTIVATOR_ACTIVITY ( 0.00911452133048107 ); HEMATOPOIETIN_INTERFERON_CLASS__D200_DOMAIN__CYTOKINE_RECEPTOR_BINDING ( 0.00946365297344109 ); ----------------GOSLIM-------------- GO:0007320 insemination ( ); GO:0007620 copulation ( ); GO:0042119 neutrophil activation ( ); GO:0007618 mating ( ); GO:0006801 superoxide metabolic process ( ); GO:0005100 Rho GTPase activator activity ( ); ----------------GO-------------- GO:0007320 insemination ( 0.00140689356625212 ); GO:0007620 copulation ( 0.00175835174640404 ); GO:0042119 neutrophil activation ( 0.00246095003967872 ); GO:0007618 mating ( 0.00351405271181626 ); GO:0006801 superoxide metabolic process ( 0.00631766894484453 ); GO:0005100 Rho GTPase activator activity ( 0.0073672804966699 ); ----------------KEGG-------------- hsa04140 Regulation of autophagy ( 0.0112077300292595 ); hsa05320 Autoimmune thyroid disease ( 0.0171179182415617 ); hsa04612 Antigen processing and presentation ( 0.0288475076651072 ); hsa04620 Toll-like receptor signaling pathway ( 0.0346671676491933 ); hsa04650 Natural killer cell mediated cytotoxicity ( 0.0452025586244847 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- Natural_killer_cell_cytotoxicity ( 0.0452025586244847 ); Antigen_processing_and_presentation ( 0.0485799780590499 ); ----------------ARE-------------- ( ); ============================ group3128 ========================= ----------------C2-------------- ( ); ----------------C3-------------- GGGYGTGNY_UNKNOWN ( 0.000457314064719373 ); TTANTCA_UNKNOWN ( 0.0012879436772093 ); V$POU1F1_Q6 ( 0.0016778138379549 ); ATGTACA,MIR-493 ( 0.00337070609553378 ); AAGCCAT,MIR-135A,MIR-135B ( 0.00390149020023385 ); TTTGTAG,MIR-520D ( 0.00395659824191409 ); TGCTGAY_UNKNOWN ( 0.00834827230161338 ); ----------------C4-------------- module_13 ( 0.000491573627907828 ); module_47 ( 0.00235592897980501 ); module_349 ( 0.0059675870928444 ); GCM_MYCL1 ( 0.00806649346022859 ); GNF2_CDH11 ( 0.00876528421499401 ); CAR_MYST2 ( 0.00946365297344109 ); GCM_ERCC4 ( 0.00981267917042006 ); ----------------C5-------------- NEUROPEPTIDE_HORMONE_ACTIVITY ( 0.00386487510436373 ); RESPIRATORY_GASEOUS_EXCHANGE ( 0.00491670716035253 ); CONDENSED_NUCLEAR_CHROMOSOME ( 0.00631766894484453 ); ADENYLATE_CYCLASE_ACTIVATION ( 0.00631766894484453 ); MEIOSIS_I ( 0.00701751562017117 ); G_PROTEIN_SIGNALING__ADENYLATE_CYCLASE_ACTIVATING_PATHWAY ( 0.00841594160042891 ); ----------------GOSLIM-------------- GO:0046539 histamine N-methyltransferase activity ( ); GO:0048645 organ formation ( ); GO:0007130 synaptonemal complex assembly ( ); GO:0070193 synaptonemal complex organization ( ); GO:0007129 synapsis ( ); GO:0070192 chromosome organization involved in meiosis ( ); GO:0042474 middle ear morphogenesis ( ); GO:0000795 synaptonemal complex ( ); GO:0048536 spleen development ( ); GO:0005184 neuropeptide hormone activity ( ); GO:0031016 pancreas development ( ); GO:0007368 determination of left/right symmetry ( ); GO:0009799 determination of symmetry ( ); GO:0009855 determination of bilateral symmetry ( ); GO:0007585 respiratory gaseous exchange ( ); ----------------GO-------------- GO:0046539 histamine N-methyltransferase activity ( 0.00035188257175911 ); GO:0048645 organ formation ( 0.00105532932820795 ); GO:0007130 synaptonemal complex assembly ( 0.00140689356625212 ); GO:0070193 synaptonemal complex organization ( 0.00140689356625212 ); GO:0007129 synapsis ( 0.00281209020611384 ); GO:0070192 chromosome organization involved in meiosis ( 0.00281209020611384 ); GO:0042474 middle ear morphogenesis ( 0.00316312442127897 ); GO:0000795 synaptonemal complex ( 0.00421559162555218 ); GO:0048536 spleen development ( 0.0056173995291634 ); GO:0005184 neuropeptide hormone activity ( 0.00666764511175721 ); GO:0031016 pancreas development ( 0.00806649346022859 ); GO:0007368 determination of left/right symmetry ( 0.00946365297344109 ); GO:0009799 determination of symmetry ( 0.00946365297344109 ); GO:0009855 determination of bilateral symmetry ( 0.00946365297344109 ); GO:0007585 respiratory gaseous exchange ( 0.00981267917042006 ); ----------------KEGG-------------- ( 0.0115562293943366 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3132 ========================= ----------------C2-------------- REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS ( 0.00631766894484453 ); KEGG_SELENOAMINO_ACID_METABOLISM ( 0.00911452133048107 ); KEGG_PENTOSE_PHOSPHATE_PATHWAY ( 0.00946365297344109 ); ----------------C3-------------- GAGCCAG,MIR-149 ( 0.000805769024084565 ); V$SEF1_C ( 0.00175835174640404 ); ----------------C4-------------- module_56 ( 0.00421559162555218 ); module_102 ( 0.00631766894484453 ); module_368 ( 0.00631766894484453 ); module_219 ( 0.00911452133048107 ); ----------------C5-------------- NEUTRAL_AMINO_ACID_TRANSPORT ( 0.00351405271181626 ); CARBOHYDRATE_KINASE_ACTIVITY ( 0.0052671062272005 ); AMINO_ACID_TRANSPORT ( 0.00911452133048107 ); ----------------GOSLIM-------------- GO:0015824 proline transport ( ); GO:0004749 ribose phosphate diphosphokinase activity ( ); GO:0016778 diphosphotransferase activity ( ); GO:0015804 neutral amino acid transport ( ); GO:0005328 neurotransmitter:sodium symporter activity ( ); GO:0009156 ribonucleoside monophosphate biosynthetic process ( ); GO:0009161 ribonucleoside monophosphate metabolic process ( ); GO:0005326 neurotransmitter transporter activity ( ); GO:0009123 nucleoside monophosphate metabolic process ( ); GO:0009124 nucleoside monophosphate biosynthetic process ( ); ----------------GO-------------- GO:0015824 proline transport ( 0.00140689356625212 ); GO:0004749 ribose phosphate diphosphokinase activity ( 0.00175835174640404 ); GO:0016778 diphosphotransferase activity ( 0.00210970389532661 ); GO:0015804 neutral amino acid transport ( 0.00456620230200799 ); GO:0005328 neurotransmitter:sodium symporter activity ( 0.00666764511175721 ); GO:0009156 ribonucleoside monophosphate biosynthetic process ( 0.00771693976783117 ); GO:0009161 ribonucleoside monophosphate metabolic process ( 0.00771693976783117 ); GO:0005326 neurotransmitter transporter activity ( 0.00771693976783117 ); GO:0009123 nucleoside monophosphate metabolic process ( 0.00806649346022859 ); GO:0009124 nucleoside monophosphate biosynthetic process ( 0.00806649346022859 ); ----------------KEGG-------------- hsa00340 Histidine metabolism ( 5.57503467938217e-05 ); hsa00440 Aminophosphonate metabolism ( 0.00386487510436373 ); hsa00450 Selenoamino acid metabolism ( 0.00876528421499401 ); hsa00030 Pentose phosphate pathway ( 0.00911452133048107 ); hsa00150 Androgen and estrogen metabolism ( 0.0139927784031002 ); hsa00350 Tyrosine metabolism ( 0.0157300169811558 ); hsa00380 Tryptophan metabolism ( 0.0174646313322848 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3154 ========================= ----------------C2-------------- KEGG_HUNTINGTONS_DISEASE ( 0.0014822834432328 ); REACTOME_XENOBIOTICS ( 0.0052671062272005 ); REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS ( 0.00631766894484453 ); KEGG_LINOLEIC_ACID_METABOLISM ( 0.00981267917042006 ); ----------------C3-------------- ( ); ----------------C4-------------- module_111 ( 0.00115699818317551 ); module_7 ( 0.0025539089930148 ); module_106 ( 0.00491670716035253 ); module_431 ( 0.0052671062272005 ); module_135 ( 0.00876528421499401 ); module_333 ( 0.00876528421499401 ); GNF2_IGF1 ( 0.00911452133048107 ); GCM_ERCC4 ( 0.00981267917042006 ); ----------------C5-------------- ( 0.00456620230200799 ); ----------------GOSLIM-------------- GO:0021997 neural plate pattern formation ( ); GO:0021999 neural plate anterioposterior pattern formation ( ); GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine ( ); GO:0018199 peptidyl-glutamine modification ( ); GO:0018262 isopeptide cross-linking ( ); GO:0008504 monoamine transmembrane transporter activity ( ); GO:0001840 neural plate development ( ); GO:0051482 elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) ( ); GO:0048813 dendrite morphogenesis ( ); GO:0018205 peptidyl-lysine modification ( ); GO:0015893 drug transport ( ); GO:0001974 blood vessel remodeling ( ); GO:0022407 regulation of cell-cell adhesion ( ); GO:0015238 drug transporter activity ( ); GO:0048661 positive regulation of smooth muscle cell proliferation ( ); GO:0009798 axis specification ( ); GO:0018149 peptide cross-linking ( ); GO:0050729 positive regulation of inflammatory response ( ); GO:0005669 transcription factor TFIID complex ( ); GO:0016358 dendrite development ( ); GO:0015844 monoamine transport ( ); GO:0048660 regulation of smooth muscle cell proliferation ( ); GO:0048659 smooth muscle cell proliferation ( ); ----------------GO-------------- GO:0021997 neural plate pattern formation ( 0.00035188257175911 ); GO:0021999 neural plate anterioposterior pattern formation ( 0.00035188257175911 ); GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine ( 0.000703659005601542 ); GO:0018199 peptidyl-glutamine modification ( 0.000703659005601542 ); GO:0018262 isopeptide cross-linking ( 0.000703659005601542 ); GO:0008504 monoamine transmembrane transporter activity ( 0.00175835174640404 ); GO:0001840 neural plate development ( 0.00210970389532661 ); GO:0051482 elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) ( 0.00246095003967872 ); GO:0048813 dendrite morphogenesis ( 0.00281209020611384 ); GO:0018205 peptidyl-lysine modification ( 0.00351405271181626 ); GO:0015893 drug transport ( 0.00386487510436373 ); GO:0001974 blood vessel remodeling ( 0.00491670716035253 ); GO:0022407 regulation of cell-cell adhesion ( 0.0052671062272005 ); GO:0015238 drug transporter activity ( 0.0052671062272005 ); GO:0048661 positive regulation of smooth muscle cell proliferation ( 0.0056173995291634 ); GO:0009798 axis specification ( 0.0059675870928444 ); GO:0018149 peptide cross-linking ( 0.00666764511175721 ); GO:0050729 positive regulation of inflammatory response ( 0.00701751562017117 ); GO:0005669 transcription factor TFIID complex ( 0.00701751562017117 ); GO:0016358 dendrite development ( 0.00771693976783117 ); GO:0015844 monoamine transport ( 0.00841594160042891 ); GO:0048660 regulation of smooth muscle cell proliferation ( 0.00841594160042891 ); GO:0048659 smooth muscle cell proliferation ( 0.00876528421499401 ); ----------------KEGG-------------- hsa00591 Linoleic acid metabolism ( 0.00981267917042006 ); hsa05040 Huntington's disease ( 0.0112077300292595 ); hsa03022 Basal transcription factors ( 0.0115562293943366 ); hsa00590 Arachidonic acid metabolism ( 0.0188504355903614 ); hsa00830 Retinol metabolism ( 0.0195427092262304 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.0216170186947268 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0223076187411271 ); hsa05012 Parkinson's disease ( 0.0390973021624058 ); ----------------CARTA-------------- ( 0.0129491742515314 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3170 ========================= ----------------C2-------------- KEGG_RENIN_ANGIOTENSIN_SYSTEM ( 0.0059675870928444 ); KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE ( 0.00771693976783117 ); KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE ( 0.00911452133048107 ); ----------------C3-------------- ( 0.00186573341189888 ); ----------------C4-------------- ( 0.00981267917042006 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ( ); GO:0001595 angiotensin receptor activity ( ); GO:0004945 angiotensin type II receptor activity ( ); GO:0006023 aminoglycan biosynthetic process ( ); GO:0006024 glycosaminoglycan biosynthetic process ( ); GO:0015020 glucuronosyltransferase activity ( ); ----------------GO-------------- GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ( 0.000703659005601542 ); GO:0001595 angiotensin receptor activity ( 0.00140689356625212 ); GO:0004945 angiotensin type II receptor activity ( 0.00140689356625212 ); GO:0006023 aminoglycan biosynthetic process ( 0.00666764511175721 ); GO:0006024 glycosaminoglycan biosynthetic process ( 0.00666764511175721 ); GO:0015020 glucuronosyltransferase activity ( 0.00666764511175721 ); ----------------KEGG-------------- hsa04614 Renin-angiotensin system ( 0.0059675870928444 ); hsa00532 Chondroitin sulfate biosynthesis ( 0.00701751562017117 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0407965536870063 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0356167680185723 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3182 ========================= ----------------C2-------------- ( ); ----------------C3-------------- GAGCCTG,MIR-484 ( 0.000382507314410278 ); V$DR1_Q3 ( 0.00156970475578505 ); V$NERF_Q2 ( 0.00169617107604503 ); V$PPAR_DR1_Q2 ( 0.00173317571836818 ); V$HFH1_01 ( 0.00180834425416679 ); CAGTATT,MIR-200B,MIR-200C,MIR-429 ( 0.00735643852936387 ); V$PAX8_01 ( 0.00981267917042006 ); ----------------C4-------------- ( ); ----------------C5-------------- 3__5__EXONUCLEASE_ACTIVITY ( 0.00386487510436373 ); PML_BODY ( 0.00491670716035253 ); HOMOPHILIC_CELL_ADHESION ( 0.0056173995291634 ); EXONUCLEASE_ACTIVITY ( 0.0059675870928444 ); DEOXYRIBONUCLEASE_ACTIVITY ( 0.0073672804966699 ); RNA_CATABOLIC_PROCESS ( 0.00771693976783117 ); DNA_CATABOLIC_PROCESS ( 0.00806649346022859 ); RIBONUCLEASE_ACTIVITY ( 0.00876528421499401 ); ----------------GOSLIM-------------- GO:0008310 single-stranded DNA specific 3'-5' exodeoxyribonuclease activity ( ); GO:0008859 exoribonuclease II activity ( ); GO:0007156 homophilic cell adhesion ( ); GO:0008296 3'-5'-exodeoxyribonuclease activity ( ); GO:0008297 single-stranded DNA specific exodeoxyribonuclease activity ( ); GO:0006537 glutamate biosynthetic process ( ); GO:0004657 proline dehydrogenase activity ( ); GO:0000738 DNA catabolic process, exonucleolytic ( ); GO:0006562 proline catabolic process ( ); GO:0016337 cell-cell adhesion ( ); GO:0004529 exodeoxyribonuclease activity ( ); GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters ( ); GO:0006560 proline metabolic process ( ); GO:0000175 3'-5'-exoribonuclease activity ( ); GO:0004532 exoribonuclease activity ( ); GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters ( ); GO:0009084 glutamine family amino acid biosynthetic process ( ); GO:0006536 glutamate metabolic process ( ); GO:0009065 glutamine family amino acid catabolic process ( ); GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters ( ); GO:0008408 3'-5' exonuclease activity ( ); GO:0016605 PML body ( ); GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors ( ); ----------------GO-------------- GO:0008310 single-stranded DNA specific 3'-5' exodeoxyribonuclease activity ( 0.00035188257175911 ); GO:0008859 exoribonuclease II activity ( 0.00035188257175911 ); GO:0007156 homophilic cell adhesion ( 0.000591399733617986 ); GO:0008296 3'-5'-exodeoxyribonuclease activity ( 0.000703659005601542 ); GO:0008297 single-stranded DNA specific exodeoxyribonuclease activity ( 0.000703659005601542 ); GO:0006537 glutamate biosynthetic process ( 0.00105532932820795 ); GO:0004657 proline dehydrogenase activity ( 0.00105532932820795 ); GO:0000738 DNA catabolic process, exonucleolytic ( 0.00140689356625212 ); GO:0006562 proline catabolic process ( 0.00140689356625212 ); GO:0016337 cell-cell adhesion ( 0.0024429714555751 ); GO:0004529 exodeoxyribonuclease activity ( 0.00246095003967872 ); GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters ( 0.00246095003967872 ); GO:0006560 proline metabolic process ( 0.00316312442127897 ); GO:0000175 3'-5'-exoribonuclease activity ( 0.00351405271181626 ); GO:0004532 exoribonuclease activity ( 0.00456620230200799 ); GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters ( 0.00456620230200799 ); GO:0009084 glutamine family amino acid biosynthetic process ( 0.00491670716035253 ); GO:0006536 glutamate metabolic process ( 0.0052671062272005 ); GO:0009065 glutamine family amino acid catabolic process ( 0.00631766894484453 ); GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters ( 0.00666764511175721 ); GO:0008408 3'-5' exonuclease activity ( 0.00806649346022859 ); GO:0016605 PML body ( 0.00841594160042891 ); GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors ( 0.00911452133048107 ); ----------------KEGG-------------- hsa00330 Arginine and proline metabolism ( 0.0122529122905473 ); hsa00564 Glycerophospholipid metabolism ( 0.0226527620498571 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3194 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00212441595498495 ); ----------------C4-------------- module_94 ( 0.00642328312588736 ); module_253 ( 0.0073672804966699 ); module_196 ( 0.00806649346022859 ); ----------------C5-------------- DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX ( 0.00491670716035253 ); BASAL_LAMINA ( 0.0073672804966699 ); CALMODULIN_BINDING ( 0.00876528421499401 ); INDUCTION_OF_APOPTOSIS_BY_EXTRACELLULAR_SIGNALS ( 0.00946365297344109 ); ----------------GOSLIM-------------- GO:0005516 calmodulin binding ( ); GO:0031013 troponin I binding ( ); GO:0004000 adenosine deaminase activity ( ); GO:0016010 dystrophin-associated glycoprotein complex ( ); GO:0019239 deaminase activity ( ); GO:0008092 cytoskeletal protein binding ( ); ----------------GO-------------- GO:0005516 calmodulin binding ( 0.000818627808782583 ); GO:0031013 troponin I binding ( 0.00175835174640404 ); GO:0004000 adenosine deaminase activity ( 0.00281209020611384 ); GO:0016010 dystrophin-associated glycoprotein complex ( 0.0052671062272005 ); GO:0019239 deaminase activity ( 0.00876528421499401 ); GO:0008092 cytoskeletal protein binding ( 0.00886593391460103 ); ----------------KEGG-------------- ( 0.0146879889531635 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO1-4_PAR-CLIP_(Hafner_2010) ( 0.0214164568040615 ); hnRNPC_iCLIP_(Koenig_2010) ( 0.0238348515334637 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0356167680185723 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3196 ========================= ----------------C2-------------- KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE ( 0.00771693976783117 ); REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC ( 0.00981267917042006 ); ----------------C3-------------- V$GABP_B ( 0.00131474811762104 ); CGCTGCT,MIR-503 ( 0.00631766894484453 ); ----------------C4-------------- GCM_NF2 ( 0.00271319466444038 ); GCM_CSNK1A1 ( 0.00981267917042006 ); ----------------C5-------------- ( 0.0059675870928444 ); ----------------GOSLIM-------------- GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity ( 0.0052671062272005 ); GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity ( 0.0052671062272005 ); GO:0035267 NuA4 histone acetyltransferase complex ( 0.0052671062272005 ); GO:0043189 H4/H2A histone acetyltransferase complex ( 0.0052671062272005 ); GO:0032580 Golgi cisterna membrane ( 0.0052671062272005 ); GO:0050998 nitric-oxide synthase binding ( 0.0052671062272005 ); GO:0000123 histone acetyltransferase complex ( 0.0052671062272005 ); GO:0016998 cell wall catabolic process ( 0.0052671062272005 ); GO:0007047 cell wall organization ( 0.0052671062272005 ); GO:0044036 cell wall metabolic process ( 0.0052671062272005 ); GO:0031985 Golgi cisterna ( 0.0052671062272005 ); GO:0045229 external encapsulating structure organization ( 0.0052671062272005 ); GO:0031984 organelle subcompartment ( 0.0052671062272005 ); GO:0015020 glucuronosyltransferase activity ( 0.0052671062272005 ); GO:0005795 Golgi stack ( 0.0052671062272005 ); ----------------GO-------------- GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity ( 0.00105532932820795 ); GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity ( 0.00140689356625212 ); GO:0035267 NuA4 histone acetyltransferase complex ( 0.00210970389532661 ); GO:0043189 H4/H2A histone acetyltransferase complex ( 0.00246095003967872 ); GO:0032580 Golgi cisterna membrane ( 0.00281209020611384 ); GO:0050998 nitric-oxide synthase binding ( 0.00281209020611384 ); GO:0000123 histone acetyltransferase complex ( 0.00386487510436373 ); GO:0016998 cell wall catabolic process ( 0.00491670716035253 ); GO:0007047 cell wall organization ( 0.0052671062272005 ); GO:0044036 cell wall metabolic process ( 0.0052671062272005 ); GO:0031985 Golgi cisterna ( 0.0056173995291634 ); GO:0045229 external encapsulating structure organization ( 0.0059675870928444 ); GO:0031984 organelle subcompartment ( 0.00631766894484453 ); GO:0015020 glucuronosyltransferase activity ( 0.00666764511175721 ); GO:0005795 Golgi stack ( 0.00946365297344109 ); ----------------KEGG-------------- hsa00532 Chondroitin sulfate biosynthesis ( 0.00701751562017117 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0178112395861112 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0178112395861112 ); hsa05110 Vibrio cholerae infection ( 0.0202345641482173 ); hsa04520 Adherens junction ( 0.0260984552159211 ); hsa04670 Leukocyte transendothelial migration ( 0.0401171624173481 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0407965536870063 ); hsa04530 Tight junction ( 0.0455407623533395 ); hsa01430 Cell junctions ( 0.0472302411935647 ); ----------------CARTA-------------- il2pathway ( 0.00666764511175721 ); eif4pathway ( 0.00841594160042891 ); ptenpathway ( 0.00911452133048107 ); mtorpathway ( 0.0146879889531635 ); il2rbpathway ( 0.0146879889531635 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3197 ========================= ----------------C2-------------- KEGG_INOSITOL_PHOSPHATE_METABOLISM ( 0.000150564902777667 ); KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM ( 0.00029876246127159 ); ----------------C3-------------- V$TCF1P_Q6 ( 0.00164138978048834 ); V$ATF3_Q6 ( 0.00188505576821623 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0035300 inositol-1,3,4-trisphosphate 5/6-kinase activity ( ); GO:0047325 inositol tetrakisphosphate 1-kinase activity ( ); GO:0051765 inositol tetrakisphosphate kinase activity ( ); GO:0032957 inositol trisphosphate metabolic process ( ); GO:0043647 inositol phosphate metabolic process ( ); GO:0004826 phenylalanine-tRNA ligase activity ( ); GO:0051766 inositol trisphosphate kinase activity ( ); GO:0005080 protein kinase C binding ( ); GO:0006020 inositol metabolic process ( ); GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( ); GO:0004435 phosphoinositide phospholipase C activity ( ); ----------------GO-------------- GO:0035300 inositol-1,3,4-trisphosphate 5/6-kinase activity ( 0.00035188257175911 ); GO:0047325 inositol tetrakisphosphate 1-kinase activity ( 0.00035188257175911 ); GO:0051765 inositol tetrakisphosphate kinase activity ( 0.000703659005601542 ); GO:0032957 inositol trisphosphate metabolic process ( 0.00140689356625212 ); GO:0043647 inositol phosphate metabolic process ( 0.00140689356625212 ); GO:0004826 phenylalanine-tRNA ligase activity ( 0.00175835174640404 ); GO:0051766 inositol trisphosphate kinase activity ( 0.00281209020611384 ); GO:0005080 protein kinase C binding ( 0.00316312442127897 ); GO:0006020 inositol metabolic process ( 0.00386487510436373 ); GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( 0.00876528421499401 ); GO:0004435 phosphoinositide phospholipase C activity ( 0.00876528421499401 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.000118803785507557 ); hsa04070 Phosphatidylinositol signaling system ( 0.00029876246127159 ); hsa04640 Hematopoietic cell lineage ( 0.0291906710899603 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3198 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_216 ( 0.00316312442127897 ); module_328 ( 0.00491670716035253 ); module_267 ( 0.0052671062272005 ); ----------------C5-------------- NICOTINIC_ACETYLCHOLINE_GATED_RECEPTOR_CHANNEL_COMPLEX ( 0.00386487510436373 ); NICOTINIC_ACETYLCHOLINE_ACTIVATED_CATION_SELECTIVE_CHANNEL_ACTIVITY ( 0.00386487510436373 ); RESPONSE_TO_TEMPERATURE_STIMULUS ( 0.0056173995291634 ); THIOLESTER_HYDROLASE_ACTIVITY ( 0.0056173995291634 ); ACETYLCHOLINE_BINDING ( 0.0059675870928444 ); EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY ( 0.0073672804966699 ); EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY ( 0.0073672804966699 ); AMINE_BINDING ( 0.00806649346022859 ); ----------------GOSLIM-------------- GO:0060084 synaptic transmission involved in micturition ( ); GO:0060073 micturition ( ); GO:0035095 behavioral response to nicotine ( ); GO:0016291 acyl-CoA thioesterase activity ( ); GO:0035094 response to nicotine ( ); GO:0005892 nicotinic acetylcholine-gated receptor-channel complex ( ); GO:0016289 CoA hydrolase activity ( ); GO:0007274 neuromuscular synaptic transmission ( ); GO:0004889 nicotinic acetylcholine-activated cation-selective channel activity ( ); GO:0015464 acetylcholine receptor activity ( ); GO:0003014 renal system process ( ); GO:0043279 response to alkaloid ( ); GO:0042166 acetylcholine binding ( ); GO:0014070 response to organic cyclic substance ( ); ----------------GO-------------- GO:0060084 synaptic transmission involved in micturition ( 0.000703659005601542 ); GO:0060073 micturition ( 0.00105532932820795 ); GO:0035095 behavioral response to nicotine ( 0.00281209020611384 ); GO:0016291 acyl-CoA thioesterase activity ( 0.00316312442127897 ); GO:0035094 response to nicotine ( 0.00386487510436373 ); GO:0005892 nicotinic acetylcholine-gated receptor-channel complex ( 0.00456620230200799 ); GO:0016289 CoA hydrolase activity ( 0.00456620230200799 ); GO:0007274 neuromuscular synaptic transmission ( 0.00491670716035253 ); GO:0004889 nicotinic acetylcholine-activated cation-selective channel activity ( 0.0052671062272005 ); GO:0015464 acetylcholine receptor activity ( 0.00631766894484453 ); GO:0003014 renal system process ( 0.00666764511175721 ); GO:0043279 response to alkaloid ( 0.00701751562017117 ); GO:0042166 acetylcholine binding ( 0.00701751562017117 ); GO:0014070 response to organic cyclic substance ( 0.00911452133048107 ); ----------------KEGG-------------- hsa00632 Benzoate degradation via CoA ligation ( 0.00491670716035253 ); hsa00903 Limonene and pinene degradation ( 0.00631766894484453 ); hsa01040 Biosynthesis of unsaturated fatty acids ( 0.0073672804966699 ); hsa05120 Epithelial cell signaling in Helicobacter pylori infection ( 0.0233427353700953 ); hsa04670 Leukocyte transendothelial migration ( 0.0401171624173481 ); hsa04514 Cell adhesion molecules (CAMs) ( 0.0448642521813974 ); hsa04120 Ubiquitin mediated proteolysis ( 0.0452025586244847 ); hsa04530 Tight junction ( 0.0455407623533395 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3199 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$ATF3_Q6 ( 0.00188505576821623 ); TGAYRTCA_V$ATF3_Q6 ( 0.00795990663253158 ); ----------------C4-------------- module_333 ( 0.00876528421499401 ); module_68 ( 0.00911452133048107 ); module_298 ( 0.00911452133048107 ); ----------------C5-------------- SINGLE_STRANDED_RNA_BINDING ( 0.00421559162555218 ); DEAMINASE_ACTIVITY ( 0.00491670716035253 ); HYDROLASE_ACTIVITY__ACTING_ON_CARBON_NITROGEN__BUT_NOT_PEPTIDE__BONDS__IN_CYCLIC_AMIDINES ( 0.0056173995291634 ); DOUBLE_STRANDED_RNA_BINDING ( 0.0059675870928444 ); ----------------GOSLIM-------------- GO:0004000 adenosine deaminase activity ( ); GO:0043190 ATP-binding cassette (ABC) transporter complex ( ); GO:0033700 phospholipid efflux ( ); GO:0016887 ATPase activity ( ); GO:0003727 single-stranded RNA binding ( ); GO:0019239 deaminase activity ( ); ----------------GO-------------- GO:0004000 adenosine deaminase activity ( 0.00281209020611384 ); GO:0043190 ATP-binding cassette (ABC) transporter complex ( 0.00316312442127897 ); GO:0033700 phospholipid efflux ( 0.00351405271181626 ); GO:0016887 ATPase activity ( 0.00441065800156651 ); GO:0003727 single-stranded RNA binding ( 0.0073672804966699 ); GO:0019239 deaminase activity ( 0.00876528421499401 ); ----------------KEGG-------------- hsa00790 Folate biosynthesis ( 0.0115562293943366 ); hsa02010 ABC transporters - General ( 0.0153827793094932 ); hsa01430 Cell junctions ( 0.0472302411935647 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3205 ========================= ----------------C2-------------- ( ); ----------------C3-------------- TCANNTGAY_V$SREBP1_01 ( 0.00625062734037582 ); TGCTGAY_UNKNOWN ( 0.00834827230161338 ); ----------------C4-------------- ( ); ----------------C5-------------- REGULATION_OF_JNK_CASCADE ( 0.00421559162555218 ); KINASE_ACTIVATOR_ACTIVITY ( 0.00421559162555218 ); REGULATION_OF_MAPKKK_CASCADE ( 0.00701751562017117 ); ----------------GOSLIM-------------- GO:0005078 MAP-kinase scaffold activity ( ); GO:0001540 beta-amyloid binding ( ); GO:0007172 signal complex assembly ( ); GO:0030295 protein kinase activator activity ( ); GO:0046328 regulation of JNK cascade ( ); GO:0045768 positive regulation of anti-apoptosis ( ); GO:0030159 receptor signaling complex scaffold activity ( ); GO:0019209 kinase activator activity ( ); GO:0032947 protein complex scaffold ( ); GO:0045767 regulation of anti-apoptosis ( ); GO:0005884 actin filament ( ); ----------------GO-------------- GO:0005078 MAP-kinase scaffold activity ( 0.000703659005601542 ); GO:0001540 beta-amyloid binding ( 0.00386487510436373 ); GO:0007172 signal complex assembly ( 0.00421559162555218 ); GO:0030295 protein kinase activator activity ( 0.00456620230200799 ); GO:0046328 regulation of JNK cascade ( 0.0052671062272005 ); GO:0045768 positive regulation of anti-apoptosis ( 0.0056173995291634 ); GO:0030159 receptor signaling complex scaffold activity ( 0.0056173995291634 ); GO:0019209 kinase activator activity ( 0.00631766894484453 ); GO:0032947 protein complex scaffold ( 0.00631766894484453 ); GO:0045767 regulation of anti-apoptosis ( 0.00666764511175721 ); GO:0005884 actin filament ( 0.00911452133048107 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3219 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$SMAD3_Q6 ( 2.28228230092739e-05 ); GTTRYCATRR_UNKNOWN ( 0.000730710619773211 ); CAGGTA_V$AREB6_01 ( 0.000751458938780347 ); V$NFMUE1_Q6 ( 0.00153444459789316 ); V$FOXO1_02 ( 0.00158748049925114 ); TGACCTTG_V$SF1_Q6 ( 0.00173317571836818 ); TGACCTY_V$ERR1_Q2 ( 0.00175863898070435 ); V$AREB6_04 ( 0.001923989134283 ); GATTGGY_V$NFY_Q6_01 ( 0.00220961376941537 ); ----------------C4-------------- module_493 ( 0.000198697691625207 ); module_19 ( 0.00461665297928142 ); module_1 ( 0.00621636082786979 ); module_60 ( 0.00795990663253158 ); GCM_BAG5 ( 0.00911452133048107 ); ----------------C5-------------- HISTONE_DEACETYLASE_COMPLEX ( 0.00631766894484453 ); CHROMATIN_REMODELING ( 0.00806649346022859 ); ----------------GOSLIM-------------- GO:0005826 contractile ring ( 0.00656299275179102 ); GO:0033033 negative regulation of myeloid cell apoptosis ( 0.00656299275179102 ); GO:0016986 transcription initiation factor activity ( 0.00656299275179102 ); GO:0033032 regulation of myeloid cell apoptosis ( 0.00656299275179102 ); GO:0043249 erythrocyte maturation ( 0.00656299275179102 ); GO:0032153 cell division site ( 0.00656299275179102 ); GO:0032155 cell division site part ( 0.00656299275179102 ); GO:0033028 myeloid cell apoptosis ( 0.00656299275179102 ); GO:0048821 erythrocyte development ( 0.00656299275179102 ); GO:0000118 histone deacetylase complex ( 0.00656299275179102 ); ----------------GO-------------- GO:0005826 contractile ring ( 0.00105532932820795 ); GO:0033033 negative regulation of myeloid cell apoptosis ( 0.00140689356625212 ); GO:0016986 transcription initiation factor activity ( 0.00140689356625212 ); GO:0033032 regulation of myeloid cell apoptosis ( 0.00210970389532661 ); GO:0043249 erythrocyte maturation ( 0.00210970389532661 ); GO:0032153 cell division site ( 0.00210970389532661 ); GO:0032155 cell division site part ( 0.00210970389532661 ); GO:0033028 myeloid cell apoptosis ( 0.00281209020611384 ); GO:0048821 erythrocyte development ( 0.00316312442127897 ); GO:0000118 histone deacetylase complex ( 0.00911452133048107 ); ----------------KEGG-------------- hsa03022 Basal transcription factors ( 0.0115562293943366 ); hsa05215 Prostate cancer ( 0.0305622856350161 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3274 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$YY1_02 ( 0.00144799598605562 ); V$TATA_01 ( 0.0024210683906478 ); ATTCTTT,MIR-186 ( 0.00264436268527345 ); GCCATNTTG_V$YY1_Q6 ( 0.00432373968355045 ); ----------------C4-------------- module_552 ( 0.00631766894484453 ); module_189 ( 0.00806649346022859 ); GNF2_MSH2 ( 0.00911452133048107 ); module_127 ( 0.00911452133048107 ); ----------------C5-------------- ( 0.00806649346022859 ); ----------------GOSLIM-------------- GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( ); GO:0004435 phosphoinositide phospholipase C activity ( ); ----------------GO-------------- GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( 0.00876528421499401 ); GO:0004435 phosphoinositide phospholipase C activity ( 0.00876528421499401 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3325 ========================= ----------------C2-------------- REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION ( 0.00351405271181626 ); BIOCARTA_LEPTIN_PATHWAY ( 0.00386487510436373 ); BIOCARTA_CTL_PATHWAY ( 0.00491670716035253 ); BIOCARTA_BCELLSURVIVAL_PATHWAY ( 0.0052671062272005 ); BIOCARTA_NKCELLS_PATHWAY ( 0.00701751562017117 ); REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS ( 0.0073672804966699 ); REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS ( 0.00981267917042006 ); ----------------C3-------------- ( ); ----------------C4-------------- module_334 ( 0.00109664952124828 ); module_144 ( 0.00281209020611384 ); module_293 ( 0.00386487510436373 ); module_143 ( 0.00456620230200799 ); GNF2_MBD4 ( 0.00771693976783117 ); GNF2_CDKN1C ( 0.00946365297344109 ); ----------------C5-------------- NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS ( 0.00386487510436373 ); ENERGY_RESERVE_METABOLIC_PROCESS ( 0.0052671062272005 ); REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS ( 0.0052671062272005 ); FEEDING_BEHAVIOR ( 0.00841594160042891 ); ----------------GOSLIM-------------- GO:0030300 regulation of cholesterol absorption ( ); GO:0032096 negative regulation of response to food ( ); GO:0032099 negative regulation of appetite ( ); GO:0045597 positive regulation of cell differentiation ( ); GO:0032105 negative regulation of response to extracellular stimulus ( ); GO:0032108 negative regulation of response to nutrient levels ( ); GO:0044058 regulation of digestive system process ( ); GO:0006111 regulation of gluconeogenesis ( ); GO:0032095 regulation of response to food ( ); GO:0032098 regulation of appetite ( ); GO:0032104 regulation of response to extracellular stimulus ( ); GO:0032107 regulation of response to nutrient levels ( ); GO:0042755 eating behavior ( ); GO:0002076 osteoblast development ( ); GO:0008343 adult feeding behavior ( ); GO:0002021 response to dietary excess ( ); GO:0030299 cholesterol absorption ( ); GO:0032094 response to food ( ); GO:0043255 regulation of carbohydrate biosynthetic process ( ); GO:0044241 lipid digestion ( ); GO:0045595 regulation of cell differentiation ( ); GO:0050810 regulation of steroid biosynthetic process ( ); GO:0050892 intestinal absorption ( ); GO:0008206 bile acid metabolic process ( ); GO:0032393 MHC class I receptor activity ( ); GO:0002474 antigen processing and presentation of peptide antigen via MHC class I ( ); GO:0010675 regulation of cellular carbohydrate metabolic process ( ); GO:0021954 central nervous system neuron development ( ); GO:0032868 response to insulin stimulus ( ); GO:0045669 positive regulation of osteoblast differentiation ( ); GO:0006109 regulation of carbohydrate metabolic process ( ); GO:0019218 regulation of steroid metabolic process ( ); GO:0006094 gluconeogenesis ( ); GO:0021953 central nervous system neuron differentiation ( ); GO:0032102 negative regulation of response to external stimulus ( ); GO:0046890 regulation of lipid biosynthetic process ( ); GO:0050796 regulation of insulin secretion ( ); GO:0048002 antigen processing and presentation of peptide antigen ( ); GO:0042612 MHC class I protein complex ( ); GO:0022600 digestive system process ( ); GO:0031901 early endosome membrane ( ); GO:0006090 pyruvate metabolic process ( ); GO:0051094 positive regulation of developmental process ( ); GO:0002791 regulation of peptide secretion ( ); GO:0019319 hexose biosynthetic process ( ); GO:0045667 regulation of osteoblast differentiation ( ); ----------------GO-------------- GO:0030300 regulation of cholesterol absorption ( 0.000703659005601542 ); GO:0032096 negative regulation of response to food ( 0.000703659005601542 ); GO:0032099 negative regulation of appetite ( 0.000703659005601542 ); GO:0045597 positive regulation of cell differentiation ( 0.00100908456654771 ); GO:0032105 negative regulation of response to extracellular stimulus ( 0.00105532932820795 ); GO:0032108 negative regulation of response to nutrient levels ( 0.00105532932820795 ); GO:0044058 regulation of digestive system process ( 0.00105532932820795 ); GO:0006111 regulation of gluconeogenesis ( 0.00175835174640404 ); GO:0032095 regulation of response to food ( 0.00175835174640404 ); GO:0032098 regulation of appetite ( 0.00210970389532661 ); GO:0032104 regulation of response to extracellular stimulus ( 0.00246095003967872 ); GO:0032107 regulation of response to nutrient levels ( 0.00246095003967872 ); GO:0042755 eating behavior ( 0.00246095003967872 ); GO:0002076 osteoblast development ( 0.00281209020611384 ); GO:0008343 adult feeding behavior ( 0.00281209020611384 ); GO:0002021 response to dietary excess ( 0.00316312442127897 ); GO:0030299 cholesterol absorption ( 0.00316312442127897 ); GO:0032094 response to food ( 0.00316312442127897 ); GO:0043255 regulation of carbohydrate biosynthetic process ( 0.00316312442127897 ); GO:0044241 lipid digestion ( 0.00386487510436373 ); GO:0045595 regulation of cell differentiation ( 0.00452782400204035 ); GO:0050810 regulation of steroid biosynthetic process ( 0.00456620230200799 ); GO:0050892 intestinal absorption ( 0.00456620230200799 ); GO:0008206 bile acid metabolic process ( 0.00491670716035253 ); GO:0032393 MHC class I receptor activity ( 0.0052671062272005 ); GO:0002474 antigen processing and presentation of peptide antigen via MHC class I ( 0.0059675870928444 ); GO:0010675 regulation of cellular carbohydrate metabolic process ( 0.00666764511175721 ); GO:0021954 central nervous system neuron development ( 0.00666764511175721 ); GO:0032868 response to insulin stimulus ( 0.00666764511175721 ); GO:0045669 positive regulation of osteoblast differentiation ( 0.00666764511175721 ); GO:0006109 regulation of carbohydrate metabolic process ( 0.0073672804966699 ); GO:0019218 regulation of steroid metabolic process ( 0.0073672804966699 ); GO:0006094 gluconeogenesis ( 0.00771693976783117 ); GO:0021953 central nervous system neuron differentiation ( 0.00771693976783117 ); GO:0032102 negative regulation of response to external stimulus ( 0.00771693976783117 ); GO:0046890 regulation of lipid biosynthetic process ( 0.00771693976783117 ); GO:0050796 regulation of insulin secretion ( 0.00771693976783117 ); GO:0048002 antigen processing and presentation of peptide antigen ( 0.00806649346022859 ); GO:0042612 MHC class I protein complex ( 0.00806649346022859 ); GO:0022600 digestive system process ( 0.00841594160042891 ); GO:0031901 early endosome membrane ( 0.00841594160042891 ); GO:0006090 pyruvate metabolic process ( 0.00911452133048107 ); GO:0051094 positive regulation of developmental process ( 0.00927391135007425 ); GO:0002791 regulation of peptide secretion ( 0.00946365297344109 ); GO:0019319 hexose biosynthetic process ( 0.00946365297344109 ); GO:0045667 regulation of osteoblast differentiation ( 0.00946365297344109 ); ----------------KEGG-------------- hsa05330 Allograft rejection ( 0.0122529122905473 ); hsa05332 Graft-versus-host disease ( 0.0136450154892503 ); hsa04940 Type I diabetes mellitus ( 0.0139927784031002 ); hsa05320 Autoimmune thyroid disease ( 0.0171179182415617 ); hsa04920 Adipocytokine signaling pathway ( 0.0229978009174007 ); hsa04612 Antigen processing and presentation ( 0.0288475076651072 ); hsa04670 Leukocyte transendothelial migration ( 0.0401171624173481 ); hsa04514 Cell adhesion molecules (CAMs) ( 0.0448642521813974 ); hsa04650 Natural killer cell mediated cytotoxicity ( 0.0452025586244847 ); hsa04530 Tight junction ( 0.0455407623533395 ); ----------------CARTA-------------- igf1mtorpathway ( 0.00911452133048107 ); metpathway ( 0.0153827793094932 ); mapkpathway ( 0.0157300169811558 ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0313991270014903 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0347280333184338 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0400582084313673 ); ----------------immu-------------- Antimicrobials ( 0.0110344563714732 ); Natural_killer_cell_cytotoxicity ( 0.0452025586244847 ); Antigen_processing_and_presentation ( 0.0485799780590499 ); ----------------ARE-------------- ( ); ============================ group3480 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_157 ( 0.000558831368687326 ); module_23 ( 0.000673455660992509 ); module_111 ( 0.00115699818317551 ); module_495 ( 0.00456620230200799 ); module_373 ( 0.00771693976783117 ); module_18 ( 0.00923273260484054 ); ----------------C5-------------- MONOSACCHARIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00351405271181626 ); SUGAR_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00386487510436373 ); SOLUTE_SODIUM_SYMPORTER_ACTIVITY ( 0.00456620230200799 ); HOMOPHILIC_CELL_ADHESION ( 0.0056173995291634 ); CARBOHYDRATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.0056173995291634 ); INTEGRAL_TO_MEMBRANE ( 0.00779613845795455 ); INTRINSIC_TO_MEMBRANE ( 0.00810466986040442 ); AMINO_ACID_CATABOLIC_PROCESS ( 0.00841594160042891 ); AMINE_CATABOLIC_PROCESS ( 0.00911452133048107 ); AROMATIC_COMPOUND_METABOLIC_PROCESS ( 0.00911452133048107 ); NITROGEN_COMPOUND_CATABOLIC_PROCESS ( 0.00981267917042006 ); ----------------GOSLIM-------------- GO:0007161 calcium-independent cell-matrix adhesion ( ); GO:0004411 homogentisate 1,2-dioxygenase activity ( ); GO:0005362 low-affinity glucose:sodium symporter activity ( ); GO:0005412 glucose:sodium symporter activity ( ); GO:0006572 tyrosine catabolic process ( ); GO:0005529 sugar binding ( ); GO:0006558 L-phenylalanine metabolic process ( ); GO:0006559 L-phenylalanine catabolic process ( ); GO:0031526 brush border membrane ( ); GO:0030246 carbohydrate binding ( ); GO:0006570 tyrosine metabolic process ( ); GO:0005355 glucose transmembrane transporter activity ( ); GO:0009074 aromatic amino acid family catabolic process ( ); GO:0015149 hexose transmembrane transporter activity ( ); GO:0015145 monosaccharide transmembrane transporter activity ( ); GO:0031253 cell projection membrane ( ); GO:0019439 aromatic compound catabolic process ( ); GO:0009072 aromatic amino acid family metabolic process ( ); GO:0005903 brush border ( ); ----------------GO-------------- GO:0007161 calcium-independent cell-matrix adhesion ( 0.00035188257175911 ); GO:0004411 homogentisate 1,2-dioxygenase activity ( 0.00035188257175911 ); GO:0005362 low-affinity glucose:sodium symporter activity ( 0.00035188257175911 ); GO:0005412 glucose:sodium symporter activity ( 0.000703659005601542 ); GO:0006572 tyrosine catabolic process ( 0.00140689356625212 ); GO:0005529 sugar binding ( 0.0014140983188647 ); GO:0006558 L-phenylalanine metabolic process ( 0.00281209020611384 ); GO:0006559 L-phenylalanine catabolic process ( 0.00281209020611384 ); GO:0031526 brush border membrane ( 0.00351405271181626 ); GO:0030246 carbohydrate binding ( 0.00379237804509815 ); GO:0006570 tyrosine metabolic process ( 0.00386487510436373 ); GO:0005355 glucose transmembrane transporter activity ( 0.00421559162555218 ); GO:0009074 aromatic amino acid family catabolic process ( 0.00456620230200799 ); GO:0015149 hexose transmembrane transporter activity ( 0.00491670716035253 ); GO:0015145 monosaccharide transmembrane transporter activity ( 0.0052671062272005 ); GO:0031253 cell projection membrane ( 0.00666764511175721 ); GO:0019439 aromatic compound catabolic process ( 0.00701751562017117 ); GO:0009072 aromatic amino acid family metabolic process ( 0.00771693976783117 ); GO:0005903 brush border ( 0.00841594160042891 ); ----------------KEGG-------------- hsa00643 Styrene degradation ( 0.00105532932820795 ); hsa00350 Tyrosine metabolism ( 0.0157300169811558 ); hsa04662 B cell receptor signaling pathway ( 0.0226527620498571 ); hsa04640 Hematopoietic cell lineage ( 0.0291906710899603 ); hsa04514 Cell adhesion molecules (CAMs) ( 0.0448642521813974 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0257543551344811 ); ----------------ARE-------------- ( ); ============================ group3529 ========================= ----------------C2-------------- BIOCARTA_CYTOKINE_PATHWAY ( 2.22180901967273e-05 ); BIOCARTA_ASBCELL_PATHWAY ( 0.00386487510436373 ); BIOCARTA_IL10_PATHWAY ( 0.0059675870928444 ); BIOCARTA_DC_PATHWAY ( 0.00771693976783117 ); KEGG_NITROGEN_METABOLISM ( 0.00806649346022859 ); KEGG_ASTHMA ( 0.00946365297344109 ); BIOCARTA_INFLAM_PATHWAY ( 0.00981267917042006 ); ----------------C3-------------- GCCNNNWTAAR_UNKNOWN ( 0.000659250478905132 ); V$TATA_01 ( 0.0024210683906478 ); WGTTNNNNNAAA_UNKNOWN ( 0.00838758029986029 ); ----------------C4-------------- MORF_TNFRSF6 ( 0.00125047104850597 ); MORF_SUPT3H ( 0.00476651543225913 ); module_294 ( 0.00631766894484453 ); module_354 ( 0.00631766894484453 ); MORF_RAD51L3 ( 0.00645807859266431 ); module_295 ( 0.0073672804966699 ); module_343 ( 0.00876528421499401 ); ----------------C5-------------- IMMUNE_RESPONSE ( 0.00266721231275327 ); EPITHELIAL_TO_MESENCHYMAL_TRANSITION ( 0.00316312442127897 ); LEUKOCYTE_CHEMOTAXIS ( 0.00386487510436373 ); LEUKOCYTE_MIGRATION ( 0.00456620230200799 ); CARBONATE_DEHYDRATASE_ACTIVITY ( 0.00456620230200799 ); IMMUNE_SYSTEM_PROCESS ( 0.00516673084819107 ); CELL_RECOGNITION ( 0.00631766894484453 ); NEGATIVE_REGULATION_OF_TRANSLATION ( 0.00771693976783117 ); ADAPTIVE_IMMUNE_RESPONSE_GO_0002460 ( 0.00806649346022859 ); ADAPTIVE_IMMUNE_RESPONSE ( 0.00841594160042891 ); HYDRO_LYASE_ACTIVITY ( 0.00946365297344109 ); NEGATIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS ( 0.00981267917042006 ); ----------------GOSLIM-------------- GO:0030886 negative regulation of myeloid dendritic cell activation ( ); GO:0045355 negative regulation of interferon-alpha biosynthetic process ( ); GO:0005141 interleukin-10 receptor binding ( ); GO:0030885 regulation of myeloid dendritic cell activation ( ); GO:0045347 negative regulation of MHC class II biosynthetic process ( ); GO:0045348 positive regulation of MHC class II biosynthetic process ( ); GO:0006935 chemotaxis ( ); GO:0042330 taxis ( ); GO:0002374 cytokine secretion during immune response ( ); GO:0002739 regulation of cytokine secretion during immune response ( ); GO:0002740 negative regulation of cytokine secretion during immune response ( ); GO:0007253 cytoplasmic sequestering of NF-kappaB ( ); GO:0032695 negative regulation of interleukin-12 production ( ); GO:0051045 negative regulation of membrane protein ectodomain proteolysis ( ); GO:0005125 cytokine activity ( ); GO:0032715 negative regulation of interleukin-6 production ( ); GO:0042347 negative regulation of NF-kappaB import into nucleus ( ); GO:0045342 MHC class II biosynthetic process ( ); GO:0045346 regulation of MHC class II biosynthetic process ( ); GO:0045349 interferon-alpha biosynthetic process ( ); GO:0045354 regulation of interferon-alpha biosynthetic process ( ); GO:0032479 regulation of type I interferon production ( ); GO:0032607 interferon-alpha production ( ); GO:0032647 regulation of interferon-alpha production ( ); GO:0007626 locomotory behavior ( ); GO:0050710 negative regulation of cytokine secretion ( ); GO:0001773 myeloid dendritic cell activation ( ); GO:0032800 receptor biosynthetic process ( ); GO:0045351 type I interferon biosynthetic process ( ); GO:0004985 opioid receptor activity ( ); GO:0032606 type I interferon production ( ); GO:0042994 cytoplasmic sequestering of transcription factor ( ); GO:0045191 regulation of isotype switching ( ); GO:0042092 T-helper 2 type immune response ( ); GO:0032615 interleukin-12 production ( ); GO:0032655 regulation of interleukin-12 production ( ); GO:0042992 negative regulation of transcription factor import into nucleus ( ); GO:0045861 negative regulation of proteolysis ( ); GO:0051220 cytoplasmic sequestering of protein ( ); GO:0050709 negative regulation of protein secretion ( ); GO:0042308 negative regulation of protein import into nucleus ( ); GO:0042345 regulation of NF-kappaB import into nucleus ( ); GO:0042348 NF-kappaB import into nucleus ( ); GO:0051043 regulation of membrane protein ectodomain proteolysis ( ); GO:0002637 regulation of immunoglobulin production ( ); GO:0008038 neuron recognition ( ); GO:0002718 regulation of cytokine production during immune response ( ); GO:0042036 negative regulation of cytokine biosynthetic process ( ); GO:0046823 negative regulation of nucleocytoplasmic transport ( ); GO:0002204 somatic recombination of immunoglobulin genes during immune response ( ); GO:0002208 somatic diversification of immunoglobulins during immune response ( ); GO:0042130 negative regulation of T cell proliferation ( ); GO:0045190 isotype switching ( ); GO:0004089 carbonate dehydratase activity ( ); GO:0001837 epithelial to mesenchymal transition ( ); GO:0002367 cytokine production during immune response ( ); GO:0002381 immunoglobulin production during immune response ( ); GO:0002712 regulation of B cell mediated immunity ( ); GO:0002889 regulation of immunoglobulin mediated immune response ( ); GO:0050715 positive regulation of cytokine secretion ( ); GO:0007610 behavior ( ); GO:0016447 somatic recombination of immunoglobulin gene segments ( ); GO:0032387 negative regulation of intracellular transport ( ); GO:0000018 regulation of DNA recombination ( ); GO:0016445 somatic diversification of immunoglobulins ( ); GO:0032945 negative regulation of mononuclear cell proliferation ( ); GO:0050672 negative regulation of lymphocyte proliferation ( ); GO:0042100 B cell proliferation ( ); GO:0050707 regulation of cytokine secretion ( ); GO:0001818 negative regulation of cytokine production ( ); GO:0032675 regulation of interleukin-6 production ( ); GO:0050868 negative regulation of T cell activation ( ); GO:0051384 response to glucocorticoid stimulus ( ); GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus ( ); GO:0016444 somatic cell DNA recombination ( ); GO:0040011 locomotion ( ); GO:0002200 somatic diversification of immune receptors ( ); GO:0002237 response to molecule of bacterial origin ( ); GO:0031960 response to corticosteroid stimulus ( ); GO:0042990 regulation of transcription factor import into nucleus ( ); GO:0042991 transcription factor import into nucleus ( ); GO:0050663 cytokine secretion ( ); GO:0006509 membrane protein ectodomain proteolysis ( ); GO:0033619 membrane protein proteolysis ( ); GO:0050714 positive regulation of protein secretion ( ); GO:0002700 regulation of production of molecular mediator of immune response ( ); GO:0032635 interleukin-6 production ( ); GO:0043112 receptor metabolic process ( ); GO:0051224 negative regulation of protein transport ( ); ----------------GO-------------- GO:0030886 negative regulation of myeloid dendritic cell activation ( 0.00035188257175911 ); GO:0045355 negative regulation of interferon-alpha biosynthetic process ( 0.00035188257175911 ); GO:0005141 interleukin-10 receptor binding ( 0.00035188257175911 ); GO:0030885 regulation of myeloid dendritic cell activation ( 0.000703659005601542 ); GO:0045347 negative regulation of MHC class II biosynthetic process ( 0.00105532932820795 ); GO:0045348 positive regulation of MHC class II biosynthetic process ( 0.00105532932820795 ); GO:0006935 chemotaxis ( 0.00114176334556899 ); GO:0042330 taxis ( 0.00114176334556899 ); GO:0002374 cytokine secretion during immune response ( 0.00140689356625212 ); GO:0002739 regulation of cytokine secretion during immune response ( 0.00140689356625212 ); GO:0002740 negative regulation of cytokine secretion during immune response ( 0.00140689356625212 ); GO:0007253 cytoplasmic sequestering of NF-kappaB ( 0.00140689356625212 ); GO:0032695 negative regulation of interleukin-12 production ( 0.00140689356625212 ); GO:0051045 negative regulation of membrane protein ectodomain proteolysis ( 0.00140689356625212 ); GO:0005125 cytokine activity ( 0.00173317571836818 ); GO:0032715 negative regulation of interleukin-6 production ( 0.00175835174640404 ); GO:0042347 negative regulation of NF-kappaB import into nucleus ( 0.00175835174640404 ); GO:0045342 MHC class II biosynthetic process ( 0.00175835174640404 ); GO:0045346 regulation of MHC class II biosynthetic process ( 0.00175835174640404 ); GO:0045349 interferon-alpha biosynthetic process ( 0.00175835174640404 ); GO:0045354 regulation of interferon-alpha biosynthetic process ( 0.00175835174640404 ); GO:0032479 regulation of type I interferon production ( 0.00210970389532661 ); GO:0032607 interferon-alpha production ( 0.00210970389532661 ); GO:0032647 regulation of interferon-alpha production ( 0.00210970389532661 ); GO:0007626 locomotory behavior ( 0.00231297802562602 ); GO:0050710 negative regulation of cytokine secretion ( 0.00246095003967872 ); GO:0001773 myeloid dendritic cell activation ( 0.00281209020611384 ); GO:0032800 receptor biosynthetic process ( 0.00281209020611384 ); GO:0045351 type I interferon biosynthetic process ( 0.00281209020611384 ); GO:0004985 opioid receptor activity ( 0.00281209020611384 ); GO:0032606 type I interferon production ( 0.00316312442127897 ); GO:0042994 cytoplasmic sequestering of transcription factor ( 0.00316312442127897 ); GO:0045191 regulation of isotype switching ( 0.00316312442127897 ); GO:0042092 T-helper 2 type immune response ( 0.00351405271181626 ); GO:0032615 interleukin-12 production ( 0.00386487510436373 ); GO:0032655 regulation of interleukin-12 production ( 0.00386487510436373 ); GO:0042992 negative regulation of transcription factor import into nucleus ( 0.00386487510436373 ); GO:0045861 negative regulation of proteolysis ( 0.00386487510436373 ); GO:0051220 cytoplasmic sequestering of protein ( 0.00386487510436373 ); GO:0050709 negative regulation of protein secretion ( 0.00421559162555218 ); GO:0042308 negative regulation of protein import into nucleus ( 0.00456620230200799 ); GO:0042345 regulation of NF-kappaB import into nucleus ( 0.00456620230200799 ); GO:0042348 NF-kappaB import into nucleus ( 0.00456620230200799 ); GO:0051043 regulation of membrane protein ectodomain proteolysis ( 0.00456620230200799 ); GO:0002637 regulation of immunoglobulin production ( 0.00491670716035253 ); GO:0008038 neuron recognition ( 0.00491670716035253 ); GO:0002718 regulation of cytokine production during immune response ( 0.0052671062272005 ); GO:0042036 negative regulation of cytokine biosynthetic process ( 0.0052671062272005 ); GO:0046823 negative regulation of nucleocytoplasmic transport ( 0.0052671062272005 ); GO:0002204 somatic recombination of immunoglobulin genes during immune response ( 0.0056173995291634 ); GO:0002208 somatic diversification of immunoglobulins during immune response ( 0.0056173995291634 ); GO:0042130 negative regulation of T cell proliferation ( 0.0056173995291634 ); GO:0045190 isotype switching ( 0.0056173995291634 ); GO:0004089 carbonate dehydratase activity ( 0.0056173995291634 ); GO:0001837 epithelial to mesenchymal transition ( 0.0059675870928444 ); GO:0002367 cytokine production during immune response ( 0.0059675870928444 ); GO:0002381 immunoglobulin production during immune response ( 0.0059675870928444 ); GO:0002712 regulation of B cell mediated immunity ( 0.0059675870928444 ); GO:0002889 regulation of immunoglobulin mediated immune response ( 0.0059675870928444 ); GO:0050715 positive regulation of cytokine secretion ( 0.0059675870928444 ); GO:0007610 behavior ( 0.00601261828815669 ); GO:0016447 somatic recombination of immunoglobulin gene segments ( 0.00631766894484453 ); GO:0032387 negative regulation of intracellular transport ( 0.00631766894484453 ); GO:0000018 regulation of DNA recombination ( 0.00666764511175721 ); GO:0016445 somatic diversification of immunoglobulins ( 0.00666764511175721 ); GO:0032945 negative regulation of mononuclear cell proliferation ( 0.00666764511175721 ); GO:0050672 negative regulation of lymphocyte proliferation ( 0.00666764511175721 ); GO:0042100 B cell proliferation ( 0.0073672804966699 ); GO:0050707 regulation of cytokine secretion ( 0.0073672804966699 ); GO:0001818 negative regulation of cytokine production ( 0.00771693976783117 ); GO:0032675 regulation of interleukin-6 production ( 0.00771693976783117 ); GO:0050868 negative regulation of T cell activation ( 0.00771693976783117 ); GO:0051384 response to glucocorticoid stimulus ( 0.00771693976783117 ); GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus ( 0.00806649346022859 ); GO:0016444 somatic cell DNA recombination ( 0.00806649346022859 ); GO:0040011 locomotion ( 0.00807551500934966 ); GO:0002200 somatic diversification of immune receptors ( 0.00841594160042891 ); GO:0002237 response to molecule of bacterial origin ( 0.00841594160042891 ); GO:0031960 response to corticosteroid stimulus ( 0.00841594160042891 ); GO:0042990 regulation of transcription factor import into nucleus ( 0.00841594160042891 ); GO:0042991 transcription factor import into nucleus ( 0.00841594160042891 ); GO:0050663 cytokine secretion ( 0.00841594160042891 ); GO:0006509 membrane protein ectodomain proteolysis ( 0.00876528421499401 ); GO:0033619 membrane protein proteolysis ( 0.00876528421499401 ); GO:0050714 positive regulation of protein secretion ( 0.00876528421499401 ); GO:0002700 regulation of production of molecular mediator of immune response ( 0.00911452133048107 ); GO:0032635 interleukin-6 production ( 0.00911452133048107 ); GO:0043112 receptor metabolic process ( 0.00981267917042006 ); GO:0051224 negative regulation of protein transport ( 0.00981267917042006 ); ----------------KEGG-------------- hsa00910 Nitrogen metabolism ( 0.00841594160042891 ); hsa05310 Asthma ( 0.00946365297344109 ); hsa05330 Allograft rejection ( 0.0122529122905473 ); hsa05320 Autoimmune thyroid disease ( 0.0171179182415617 ); hsa04660 T cell receptor signaling pathway ( 0.0326165928740267 ); hsa05322 Systemic lupus erythematosus ( 0.0435099987467595 ); ----------------CARTA-------------- no2il12pathway ( 0.00421559162555218 ); il2rbpathway ( 0.0146879889531635 ); ----------------RBP-------------- ( ); ----------------immu-------------- Cytokines ( 0.00943947082113285 ); TCR_signalling_pathway ( 0.0336423464661194 ); ----------------ARE-------------- ( ); ============================ group3547 ========================= ----------------C2-------------- REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL ( 0.0059675870928444 ); KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS ( 0.00876528421499401 ); REACTOME_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS ( 0.00911452133048107 ); KEGG_PENTOSE_PHOSPHATE_PATHWAY ( 0.00946365297344109 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0004139 deoxyribose-phosphate aldolase activity ( ); GO:0046121 deoxyribonucleoside catabolic process ( ); GO:0009120 deoxyribonucleoside metabolic process ( ); GO:0016832 aldehyde-lyase activity ( ); GO:0009164 nucleoside catabolic process ( ); GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process ( ); GO:0034656 nucleobase, nucleoside and nucleotide catabolic process ( ); GO:0009264 deoxyribonucleotide catabolic process ( ); GO:0016254 preassembly of GPI anchor in ER membrane ( ); GO:0009262 deoxyribonucleotide metabolic process ( ); ----------------GO-------------- GO:0004139 deoxyribose-phosphate aldolase activity ( 0.00035188257175911 ); GO:0046121 deoxyribonucleoside catabolic process ( 0.00105532932820795 ); GO:0009120 deoxyribonucleoside metabolic process ( 0.00140689356625212 ); GO:0016832 aldehyde-lyase activity ( 0.00175835174640404 ); GO:0009164 nucleoside catabolic process ( 0.00210970389532661 ); GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process ( 0.00246095003967872 ); GO:0034656 nucleobase, nucleoside and nucleotide catabolic process ( 0.00246095003967872 ); GO:0009264 deoxyribonucleotide catabolic process ( 0.00421559162555218 ); GO:0016254 preassembly of GPI anchor in ER membrane ( 0.0056173995291634 ); GO:0009262 deoxyribonucleotide metabolic process ( 0.00666764511175721 ); ----------------KEGG-------------- hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis ( 0.00806649346022859 ); hsa00030 Pentose phosphate pathway ( 0.00911452133048107 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0178112395861112 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0178112395861112 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0219623709648665 ); hsa04540 Gap junction ( 0.0333005322379875 ); ----------------CARTA-------------- ( 0.00281209020611384 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3645 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00946365297344109 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( ); ----------------KEGG-------------- hsa00510 N-Glycan biosynthesis ( 0.0146879889531635 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0407965536870063 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0214164568040615 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3713 ========================= ----------------C2-------------- REACTOME_HDL_MEDIATED_LIPID_TRANSPORT ( 0.00386487510436373 ); REACTOME_LIPOPROTEIN_METABOLISM ( 0.00946365297344109 ); ----------------C3-------------- V$CREB_Q4_01 ( 0.00128241367203276 ); V$CREB_Q2_01 ( 0.00138059084757662 ); TGACGTCA_V$ATF3_Q6 ( 0.00155202610512475 ); V$DR4_Q2 ( 0.00171462505301568 ); V$SRF_Q5_01 ( 0.00180834425416679 ); V$CREB_01 ( 0.00196330703604582 ); V$CREBP1CJUN_01 ( 0.0019831100620413 ); V$GFI1_01 ( 0.0019831100620413 ); TGGNNNNNNKCCAR_UNKNOWN ( 0.00485751925958995 ); TGAYRTCA_V$ATF3_Q6 ( 0.00795990663253158 ); ----------------C4-------------- ( ); ----------------C5-------------- CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00351405271181626 ); INTERLEUKIN_1_SECRETION ( 0.00351405271181626 ); LYSOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00386487510436373 ); VACUOLE_ORGANIZATION_AND_BIOGENESIS ( 0.00421559162555218 ); CDC42_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00421559162555218 ); MALE_GONAD_DEVELOPMENT ( 0.00421559162555218 ); PHOSPHOLIPID_TRANSPORTER_ACTIVITY ( 0.00421559162555218 ); ENDOCYTIC_VESICLE ( 0.00491670716035253 ); LIPID_HOMEOSTASIS ( 0.0056173995291634 ); CYTOKINE_SECRETION ( 0.0059675870928444 ); NUCLEOTIDE_BIOSYNTHETIC_PROCESS ( 0.00631766894484453 ); ENDOSOME_TRANSPORT ( 0.00806649346022859 ); DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS ( 0.00911452133048107 ); LIPID_TRANSPORTER_ACTIVITY ( 0.00946365297344109 ); LIPID_RAFT ( 0.00981267917042006 ); LIPID_TRANSPORT ( 0.00981267917042006 ); ----------------GOSLIM-------------- GO:0048627 myoblast development ( ); GO:0034188 apolipoprotein A-I receptor activity ( ); GO:0030226 apolipoprotein receptor activity ( ); GO:0030349 syntaxin-13 binding ( ); GO:0034186 apolipoprotein A-I binding ( ); GO:0033363 secretory granule organization ( ); GO:0055091 phospholipid homeostasis ( ); GO:0060155 platelet dense granule organization ( ); GO:0030816 positive regulation of cAMP metabolic process ( ); GO:0030819 positive regulation of cAMP biosynthetic process ( ); GO:0032366 intracellular sterol transport ( ); GO:0032367 intracellular cholesterol transport ( ); GO:0045335 phagocytic vesicle ( ); GO:0043403 skeletal muscle regeneration ( ); GO:0034185 apolipoprotein binding ( ); GO:0030801 positive regulation of cyclic nucleotide metabolic process ( ); GO:0030804 positive regulation of cyclic nucleotide biosynthetic process ( ); GO:0030810 positive regulation of nucleotide biosynthetic process ( ); GO:0045981 positive regulation of nucleotide metabolic process ( ); GO:0032365 intracellular lipid transport ( ); GO:0032488 Cdc42 protein signal transduction ( ); GO:0043691 reverse cholesterol transport ( ); GO:0033700 phospholipid efflux ( ); GO:0045843 negative regulation of striated muscle development ( ); GO:0004526 ribonuclease P activity ( ); GO:0017127 cholesterol transporter activity ( ); GO:0048635 negative regulation of muscle development ( ); GO:0004549 tRNA-specific ribonuclease activity ( ); GO:0015248 sterol transporter activity ( ); GO:0033344 cholesterol efflux ( ); GO:0050702 interleukin-1 beta secretion ( ); GO:0042246 tissue regeneration ( ); GO:0050701 interleukin-1 secretion ( ); GO:0015485 cholesterol binding ( ); GO:0019905 syntaxin binding ( ); GO:0007040 lysosome organization ( ); GO:0045445 myoblast differentiation ( ); GO:0045834 positive regulation of lipid metabolic process ( ); GO:0000149 SNARE binding ( ); GO:0007033 vacuole organization ( ); GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters ( ); GO:0032934 sterol binding ( ); GO:0031099 regeneration ( ); GO:0050663 cytokine secretion ( ); GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( ); GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters ( ); GO:0010742 foam cell differentiation ( ); GO:0008584 male gonad development ( ); ----------------GO-------------- GO:0048627 myoblast development ( 0.00035188257175911 ); GO:0034188 apolipoprotein A-I receptor activity ( 0.00035188257175911 ); GO:0030226 apolipoprotein receptor activity ( 0.000703659005601542 ); GO:0030349 syntaxin-13 binding ( 0.000703659005601542 ); GO:0034186 apolipoprotein A-I binding ( 0.000703659005601542 ); GO:0033363 secretory granule organization ( 0.00140689356625212 ); GO:0055091 phospholipid homeostasis ( 0.00140689356625212 ); GO:0060155 platelet dense granule organization ( 0.00140689356625212 ); GO:0030816 positive regulation of cAMP metabolic process ( 0.00175835174640404 ); GO:0030819 positive regulation of cAMP biosynthetic process ( 0.00175835174640404 ); GO:0032366 intracellular sterol transport ( 0.00175835174640404 ); GO:0032367 intracellular cholesterol transport ( 0.00175835174640404 ); GO:0045335 phagocytic vesicle ( 0.00175835174640404 ); GO:0043403 skeletal muscle regeneration ( 0.00210970389532661 ); GO:0034185 apolipoprotein binding ( 0.00210970389532661 ); GO:0030801 positive regulation of cyclic nucleotide metabolic process ( 0.00246095003967872 ); GO:0030804 positive regulation of cyclic nucleotide biosynthetic process ( 0.00246095003967872 ); GO:0030810 positive regulation of nucleotide biosynthetic process ( 0.00246095003967872 ); GO:0045981 positive regulation of nucleotide metabolic process ( 0.00246095003967872 ); GO:0032365 intracellular lipid transport ( 0.00281209020611384 ); GO:0032488 Cdc42 protein signal transduction ( 0.00281209020611384 ); GO:0043691 reverse cholesterol transport ( 0.00316312442127897 ); GO:0033700 phospholipid efflux ( 0.00351405271181626 ); GO:0045843 negative regulation of striated muscle development ( 0.00351405271181626 ); GO:0004526 ribonuclease P activity ( 0.00351405271181626 ); GO:0017127 cholesterol transporter activity ( 0.00351405271181626 ); GO:0048635 negative regulation of muscle development ( 0.00386487510436373 ); GO:0004549 tRNA-specific ribonuclease activity ( 0.00421559162555218 ); GO:0015248 sterol transporter activity ( 0.00421559162555218 ); GO:0033344 cholesterol efflux ( 0.00456620230200799 ); GO:0050702 interleukin-1 beta secretion ( 0.00456620230200799 ); GO:0042246 tissue regeneration ( 0.00491670716035253 ); GO:0050701 interleukin-1 secretion ( 0.00491670716035253 ); GO:0015485 cholesterol binding ( 0.0052671062272005 ); GO:0019905 syntaxin binding ( 0.0056173995291634 ); GO:0007040 lysosome organization ( 0.00701751562017117 ); GO:0045445 myoblast differentiation ( 0.00701751562017117 ); GO:0045834 positive regulation of lipid metabolic process ( 0.0073672804966699 ); GO:0000149 SNARE binding ( 0.0073672804966699 ); GO:0007033 vacuole organization ( 0.00771693976783117 ); GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters ( 0.00771693976783117 ); GO:0032934 sterol binding ( 0.00771693976783117 ); GO:0031099 regeneration ( 0.00806649346022859 ); GO:0050663 cytokine secretion ( 0.00841594160042891 ); GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( 0.00846645282898412 ); GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters ( 0.00876528421499401 ); GO:0010742 foam cell differentiation ( 0.00946365297344109 ); GO:0008584 male gonad development ( 0.00981267917042006 ); ----------------KEGG-------------- ( 0.0153827793094932 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3771 ========================= ----------------C2-------------- ( 0.00631766894484453 ); ----------------C3-------------- ( 0.00218641109974633 ); ----------------C4-------------- ( 0.00806649346022859 ); ----------------C5-------------- ( 0.00946365297344109 ); ----------------GOSLIM-------------- GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity ( ); GO:0008649 rRNA methyltransferase activity ( ); GO:0016433 rRNA (adenine) methyltransferase activity ( ); GO:0046541 saliva secretion ( ); GO:0000154 rRNA modification ( ); GO:0043550 regulation of lipid kinase activity ( ); GO:0015279 store-operated calcium channel activity ( ); GO:0043034 costamere ( ); GO:0017119 Golgi transport complex ( ); GO:0006891 intra-Golgi vesicle-mediated transport ( ); GO:0008173 RNA methyltransferase activity ( ); GO:0007589 body fluid secretion ( ); GO:0022600 digestive system process ( ); ----------------GO-------------- GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity ( 0.00105532932820795 ); GO:0008649 rRNA methyltransferase activity ( 0.00105532932820795 ); GO:0016433 rRNA (adenine) methyltransferase activity ( 0.00105532932820795 ); GO:0046541 saliva secretion ( 0.00140689356625212 ); GO:0000154 rRNA modification ( 0.00210970389532661 ); GO:0043550 regulation of lipid kinase activity ( 0.00210970389532661 ); GO:0015279 store-operated calcium channel activity ( 0.00210970389532661 ); GO:0043034 costamere ( 0.00246095003967872 ); GO:0017119 Golgi transport complex ( 0.00316312442127897 ); GO:0006891 intra-Golgi vesicle-mediated transport ( 0.0056173995291634 ); GO:0008173 RNA methyltransferase activity ( 0.00631766894484453 ); GO:0007589 body fluid secretion ( 0.00666764511175721 ); GO:0022600 digestive system process ( 0.00841594160042891 ); ----------------KEGG-------------- hsa04350 TGF-beta signaling pathway ( 0.0298766861408931 ); hsa04110 Cell cycle ( 0.0387571424129942 ); ----------------CARTA-------------- ( 0.00631766894484453 ); ----------------RBP-------------- ( 0.0138780416334507 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group24 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00127251495988553 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0043537 negative regulation of blood vessel endothelial cell migration ( ); GO:0016477 cell migration ( ); GO:0048870 cell motility ( ); GO:0030496 midbody ( ); GO:0022603 regulation of anatomical structure morphogenesis ( ); GO:0043535 regulation of blood vessel endothelial cell migration ( ); GO:0010596 negative regulation of endothelial cell migration ( ); GO:0030516 regulation of axon extension ( ); GO:0045727 positive regulation of translation ( ); GO:0001937 negative regulation of endothelial cell proliferation ( ); GO:0043534 blood vessel endothelial cell migration ( ); GO:0010594 regulation of endothelial cell migration ( ); GO:0040011 locomotion ( ); GO:0048675 axon extension ( ); GO:0016525 negative regulation of angiogenesis ( ); GO:0006928 cell motion ( ); GO:0051674 localization of cell ( ); GO:0001936 regulation of endothelial cell proliferation ( ); GO:0001709 cell fate determination ( ); GO:0001935 endothelial cell proliferation ( ); GO:0050770 regulation of axonogenesis ( ); GO:0010769 regulation of cell morphogenesis involved in differentiation ( ); GO:0043542 endothelial cell migration ( ); ----------------GO-------------- GO:0043537 negative regulation of blood vessel endothelial cell migration ( 0.00241078715875942 ); GO:0016477 cell migration ( 0.00261714182621017 ); GO:0048870 cell motility ( 0.00293324962280389 ); GO:0030496 midbody ( 0.00331358277321803 ); GO:0022603 regulation of anatomical structure morphogenesis ( 0.00341787860723127 ); GO:0043535 regulation of blood vessel endothelial cell migration ( 0.00361436330351461 ); GO:0010596 negative regulation of endothelial cell migration ( 0.00391506818858967 ); GO:0030516 regulation of axon extension ( 0.00391506818858967 ); GO:0045727 positive regulation of translation ( 0.00421569744366346 ); GO:0001937 negative regulation of endothelial cell proliferation ( 0.00451625108395437 ); GO:0043534 blood vessel endothelial cell migration ( 0.00481672912467745 ); GO:0010594 regulation of endothelial cell migration ( 0.00571770980156594 ); GO:0040011 locomotion ( 0.00584646857696773 ); GO:0048675 axon extension ( 0.00601788559613137 ); GO:0016525 negative regulation of angiogenesis ( 0.00631798586717336 ); GO:0006928 cell motion ( 0.00675095890488045 ); GO:0051674 localization of cell ( 0.00675095890488045 ); GO:0001936 regulation of endothelial cell proliferation ( 0.00721783369117057 ); GO:0001709 cell fate determination ( 0.0087160710124411 ); GO:0001935 endothelial cell proliferation ( 0.0087160710124411 ); GO:0050770 regulation of axonogenesis ( 0.0087160710124411 ); GO:0010769 regulation of cell morphogenesis involved in differentiation ( 0.00991330381611599 ); GO:0043542 endothelial cell migration ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group27 ========================= ----------------C2-------------- REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS ( 0.00481672912467745 ); REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS ( 0.0087160710124411 ); ----------------C3-------------- V$PTF1BETA_Q6 ( 0.00114054752067503 ); GGCGGCA,MIR-371 ( 0.00150731018915273 ); GATAAGR_V$GATA_C ( 0.00193628171972701 ); TTGCACT,MIR-130A,MIR-301,MIR-130B ( 0.00407925718790373 ); ----------------C4-------------- module_262 ( 0.00541745846827335 ); module_191 ( 0.00571770980156594 ); module_400 ( 0.00571770980156594 ); GNF2_SERPINI2 ( 0.00631798586717336 ); GNF2_SPINK1 ( 0.00721783369117057 ); module_382 ( 0.00841657438250376 ); ----------------C5-------------- ENDOTHELIAL_CELL_MIGRATION ( 0.00301272658247675 ); MYOSIN_COMPLEX ( 0.00481672912467745 ); RESPONSE_TO_NUTRIENT ( 0.00511713158104687 ); RESPONSE_TO_NUTRIENT_LEVELS ( 0.0087160710124411 ); RESPONSE_TO_EXTRACELLULAR_STIMULUS ( 0.00991330381611599 ); ----------------GOSLIM-------------- GO:0031638 zymogen activation ( ); GO:0030286 dynein complex ( ); GO:0005615 extracellular space ( ); GO:0043542 endothelial cell migration ( ); ----------------GO-------------- GO:0031638 zymogen activation ( 0.00241078715875942 ); GO:0030286 dynein complex ( 0.0087160710124411 ); GO:0005615 extracellular space ( 0.0096112244865944 ); GO:0043542 endothelial cell migration ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group28 ========================= ----------------C2-------------- ( 0.00451625108395437 ); ----------------C3-------------- CACCAGC,MIR-138 ( 0.00110233228682902 ); CCTGCTG,MIR-214 ( 0.00135507113779753 ); TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 ( 0.00925869683200967 ); CGGAARNGGCNG_UNKNOWN ( 0.00991330381611599 ); ----------------C4-------------- ( ); ----------------C5-------------- DRUG_BINDING ( 0.00451625108395437 ); NUCLEAR_BODY ( 0.00961410864225021 ); RNA_SPLICING__VIA_TRANSESTERIFICATION_REACTIONS ( 0.00961410864225021 ); ----------------GOSLIM-------------- GO:0016604 nuclear body ( 0.00482182493508466 ); GO:0006608 snRNP protein import into nucleus ( 0.00482182493508466 ); GO:0005681 spliceosome ( 0.00482182493508466 ); GO:0016018 cyclosporin A binding ( 0.00482182493508466 ); GO:0008380 RNA splicing ( 0.00482182493508466 ); GO:0006397 mRNA processing ( 0.00482182493508466 ); GO:0016071 mRNA metabolic process ( 0.00482182493508466 ); GO:0005086 ARF guanyl-nucleotide exchange factor activity ( 0.00482182493508466 ); GO:0030529 ribonucleoprotein complex ( 0.00482182493508466 ); GO:0044451 nucleoplasm part ( 0.00482182493508466 ); GO:0000387 spliceosomal snRNP biogenesis ( 0.00482182493508466 ); GO:0007264 small GTPase mediated signal transduction ( 0.00482182493508466 ); GO:0000245 spliceosome assembly ( 0.00482182493508466 ); GO:0006396 RNA processing ( 0.00482182493508466 ); GO:0008144 drug binding ( 0.00482182493508466 ); GO:0003755 peptidyl-prolyl cis-trans isomerase activity ( 0.00482182493508466 ); ----------------GO-------------- GO:0016604 nuclear body ( 0.000541678446918116 ); GO:0006608 snRNP protein import into nucleus ( 0.000603151453075101 ); GO:0005681 spliceosome ( 0.000634462285737334 ); GO:0016018 cyclosporin A binding ( 0.00180854491053573 ); GO:0008380 RNA splicing ( 0.00261714182621017 ); GO:0006397 mRNA processing ( 0.00311865652608249 ); GO:0016071 mRNA metabolic process ( 0.0038912364318254 ); GO:0005086 ARF guanyl-nucleotide exchange factor activity ( 0.00481672912467745 ); GO:0030529 ribonucleoprotein complex ( 0.00598821096135116 ); GO:0044451 nucleoplasm part ( 0.00627648737278352 ); GO:0000387 spliceosomal snRNP biogenesis ( 0.00781735490152924 ); GO:0007264 small GTPase mediated signal transduction ( 0.00784512957680962 ); GO:0000245 spliceosome assembly ( 0.00841657438250376 ); GO:0006396 RNA processing ( 0.00857200176943564 ); GO:0008144 drug binding ( 0.00901549225559073 ); GO:0003755 peptidyl-prolyl cis-trans isomerase activity ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group29 ========================= ----------------C2-------------- ( 0.00451625108395437 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0003774 motor activity ( ); GO:0003810 protein-glutamine gamma-glutamyltransferase activity ( ); GO:0003824 catalytic activity ( ); GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen ( ); GO:0005863 striated muscle thick filament ( ); GO:0032982 myosin filament ( ); GO:0016755 transferase activity, transferring amino-acyl groups ( ); GO:0018149 peptide cross-linking ( ); GO:0005859 muscle myosin complex ( ); GO:0016460 myosin II complex ( ); ----------------GO-------------- GO:0003774 motor activity ( 0.000673590860751732 ); GO:0003810 protein-glutamine gamma-glutamyltransferase activity ( 0.00241078715875942 ); GO:0003824 catalytic activity ( 0.00389207084963865 ); GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen ( 0.00481672912467745 ); GO:0005863 striated muscle thick filament ( 0.00511713158104687 ); GO:0032982 myosin filament ( 0.00511713158104687 ); GO:0016755 transferase activity, transferring amino-acyl groups ( 0.00511713158104687 ); GO:0018149 peptide cross-linking ( 0.00571770980156594 ); GO:0005859 muscle myosin complex ( 0.0069179598994944 ); GO:0016460 myosin II complex ( 0.0075176320201179 ); ----------------KEGG-------------- hsa00232 Caffeine metabolism ( 0.00210970389532639 ); hsa00983 Drug metabolism - other enzymes ( 0.0131994825443676 ); hsa00830 Retinol metabolism ( 0.0167740335021956 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0191510676438879 ); hsa04530 Tight junction ( 0.0391632063235058 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group41 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_103 ( 0.00361436330351461 ); module_307 ( 0.00721783369117057 ); ----------------C5-------------- CYTOCHROME_C_OXIDASE_ACTIVITY ( 0.00391506818858967 ); RESPIRATORY_GASEOUS_EXCHANGE ( 0.00421569744366346 ); HYDROGEN_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.0081170023505952 ); MONOVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00991330381611599 ); ----------------GOSLIM-------------- GO:0031966 mitochondrial membrane ( ); GO:0005740 mitochondrial envelope ( ); GO:0004129 cytochrome-c oxidase activity ( ); GO:0015002 heme-copper terminal oxidase activity ( ); GO:0016675 oxidoreductase activity, acting on heme group of donors ( ); GO:0016676 oxidoreductase activity, acting on heme group of donors, oxygen as acceptor ( ); GO:0007585 respiratory gaseous exchange ( ); GO:0044429 mitochondrial part ( ); ----------------GO-------------- GO:0031966 mitochondrial membrane ( 0.00424723971303218 ); GO:0005740 mitochondrial envelope ( 0.0046939722662892 ); GO:0004129 cytochrome-c oxidase activity ( 0.0069179598994944 ); GO:0015002 heme-copper terminal oxidase activity ( 0.0069179598994944 ); GO:0016675 oxidoreductase activity, acting on heme group of donors ( 0.0069179598994944 ); GO:0016676 oxidoreductase activity, acting on heme group of donors, oxygen as acceptor ( 0.0069179598994944 ); GO:0007585 respiratory gaseous exchange ( 0.00841657438250376 ); GO:0044429 mitochondrial part ( 0.00922377972686812 ); ----------------KEGG-------------- hsa05012 Parkinson's disease ( 0.0336061519219054 ); hsa00190 Oxidative phosphorylation ( 0.0338992946462974 ); hsa05010 Alzheimer's disease ( 0.0470142461849546 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0394194920662926 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group42 ========================= ----------------C2-------------- ( ); ----------------C3-------------- CCANNAGRKGGC_UNKNOWN ( 0.00026765399877913 ); V$NFKAPPAB65_01 ( 0.00127251495988553 ); V$OCT1_05 ( 0.00146907128577526 ); V$OCT1_Q6 ( 0.00148363606922915 ); V$OCT_Q6 ( 0.00149827070328985 ); V$CREL_01 ( 0.00151297515882745 ); V$OCT_C ( 0.00155750716310295 ); V$OCT1_Q5_01 ( 0.00158754373959111 ); TGGAAA_V$NFAT_Q4_01 ( 0.00570508396397849 ); GTCAACC,MIR-380-5P ( 0.00571770980156594 ); ----------------C4-------------- ( ); ----------------C5-------------- SIALYLTRANSFERASE_ACTIVITY ( 0.00301272658247675 ); OLIGOSACCHARIDE_METABOLIC_PROCESS ( 0.00331358277321803 ); BIOGENIC_AMINE_METABOLIC_PROCESS ( 0.00481672912467745 ); CELL_RECOGNITION ( 0.00541745846827335 ); BASAL_LAMINA ( 0.00631798586717336 ); AMINO_ACID_DERIVATIVE_METABOLIC_PROCESS ( 0.0069179598994944 ); REGULATION_OF_NEUROTRANSMITTER_LEVELS ( 0.00721783369117057 ); AMINE_CATABOLIC_PROCESS ( 0.00781735490152924 ); NITROGEN_COMPOUND_CATABOLIC_PROCESS ( 0.00841657438250376 ); ----------------GOSLIM-------------- GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity ( ); GO:0001507 acetylcholine catabolic process in synaptic cleft ( ); GO:0006581 acetylcholine catabolic process ( ); GO:0008291 acetylcholine metabolic process ( ); GO:0042135 neurotransmitter catabolic process ( ); GO:0042439 ethanolamine and derivative metabolic process ( ); GO:0008105 asymmetric protein localization ( ); GO:0005605 basal lamina ( ); GO:0007271 synaptic transmission, cholinergic ( ); GO:0008038 neuron recognition ( ); GO:0042402 biogenic amine catabolic process ( ); GO:0042133 neurotransmitter metabolic process ( ); GO:0009311 oligosaccharide metabolic process ( ); GO:0042219 amino acid derivative catabolic process ( ); GO:0008373 sialyltransferase activity ( ); GO:0016339 calcium-dependent cell-cell adhesion ( ); GO:0030054 cell junction ( ); ----------------GO-------------- GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity ( 0.000301613632936237 ); GO:0001507 acetylcholine catabolic process in synaptic cleft ( 0.000603151453075101 ); GO:0006581 acetylcholine catabolic process ( 0.000603151453075101 ); GO:0008291 acetylcholine metabolic process ( 0.000904613475662286 ); GO:0042135 neurotransmitter catabolic process ( 0.00180854491053573 ); GO:0042439 ethanolamine and derivative metabolic process ( 0.00180854491053573 ); GO:0008105 asymmetric protein localization ( 0.00301272658247675 ); GO:0005605 basal lamina ( 0.00361436330351461 ); GO:0007271 synaptic transmission, cholinergic ( 0.00391506818858967 ); GO:0008038 neuron recognition ( 0.00421569744366346 ); GO:0042402 biogenic amine catabolic process ( 0.00421569744366346 ); GO:0042133 neurotransmitter metabolic process ( 0.00481672912467745 ); GO:0009311 oligosaccharide metabolic process ( 0.00541745846827335 ); GO:0042219 amino acid derivative catabolic process ( 0.00541745846827335 ); GO:0008373 sialyltransferase activity ( 0.00571770980156594 ); GO:0016339 calcium-dependent cell-cell adhesion ( 0.00631798586717336 ); GO:0030054 cell junction ( 0.00758826757139606 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group1504 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00931483812713418 ); ----------------C4-------------- module_214 ( 0.0081170023505952 ); module_202 ( 0.00841657438250376 ); module_524 ( 0.00901549225559073 ); ----------------C5-------------- PHOTOTRANSDUCTION ( 0.00391506818858967 ); NEGATIVE_REGULATION_OF_CELL_MIGRATION ( 0.00421569744366346 ); MYOFIBRIL ( 0.00571770980156594 ); DETECTION_OF_ABIOTIC_STIMULUS ( 0.00571770980156594 ); DETECTION_OF_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION ( 0.00631798586717336 ); CONTRACTILE_FIBER_PART ( 0.0069179598994944 ); DETECTION_OF_EXTERNAL_STIMULUS ( 0.0069179598994944 ); CONTRACTILE_FIBER ( 0.0075176320201179 ); ACTIN_FILAMENT_BINDING ( 0.0075176320201179 ); REGULATION_OF_CELL_MIGRATION ( 0.0081170023505952 ); CALCIUM_ION_TRANSPORT ( 0.0081170023505952 ); SKELETAL_MUSCLE_DEVELOPMENT ( 0.00931483812713418 ); DI___TRI_VALENT_INORGANIC_CATION_TRANSPORT ( 0.00961410864225021 ); CALCIUM_CHANNEL_ACTIVITY ( 0.00991330381611599 ); ----------------GOSLIM-------------- GO:0030016 myofibril ( ); GO:0044449 contractile fiber part ( ); GO:0043292 contractile fiber ( ); GO:0033612 receptor serine/threonine kinase binding ( ); GO:0014706 striated muscle development ( ); GO:0010614 negative regulation of cardiac muscle hypertrophy ( ); GO:0010616 negative regulation of cardiac muscle adaptation ( ); GO:0014741 negative regulation of muscle hypertrophy ( ); GO:0055009 atrial cardiac muscle morphogenesis ( ); GO:0060045 positive regulation of cardiac muscle cell proliferation ( ); GO:0010613 positive regulation of cardiac muscle hypertrophy ( ); GO:0010615 positive regulation of cardiac muscle adaptation ( ); GO:0014742 positive regulation of muscle hypertrophy ( ); GO:0014744 positive regulation of muscle adaptation ( ); GO:0014745 negative regulation of muscle adaptation ( ); GO:0060343 trabecula formation ( ); GO:0060347 heart trabecula formation ( ); GO:0017025 TATA-binding protein binding ( ); GO:0007517 muscle development ( ); GO:0055015 ventricular cardiac muscle cell development ( ); GO:0030036 actin cytoskeleton organization ( ); GO:0010611 regulation of cardiac muscle hypertrophy ( ); GO:0010612 regulation of cardiac muscle adaptation ( ); GO:0014743 regulation of muscle hypertrophy ( ); GO:0014887 cardiac muscle adaptation ( ); GO:0014888 striated muscle adaptation ( ); GO:0014897 striated muscle hypertrophy ( ); GO:0014898 cardiac muscle hypertrophy ( ); GO:0015279 store-operated calcium channel activity ( ); GO:0030029 actin filament-based process ( ); GO:0043502 regulation of muscle adaptation ( ); GO:0055012 ventricular cardiac muscle cell differentiation ( ); GO:0060043 regulation of cardiac muscle cell proliferation ( ); GO:0043034 costamere ( ); GO:0014896 muscle hypertrophy ( ); GO:0055007 cardiac muscle cell differentiation ( ); GO:0055013 cardiac muscle cell development ( ); GO:0007512 adult heart development ( ); GO:0032924 activin receptor signaling pathway ( ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( ); GO:0014855 striated muscle cell proliferation ( ); GO:0043500 muscle adaptation ( ); GO:0045214 sarcomere organization ( ); GO:0060038 cardiac muscle cell proliferation ( ); GO:0010596 negative regulation of endothelial cell migration ( ); GO:0035051 cardiac cell differentiation ( ); GO:0032268 regulation of cellular protein metabolic process ( ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( ); GO:0002020 protease binding ( ); GO:0007010 cytoskeleton organization ( ); GO:0060389 pathway-restricted SMAD protein phosphorylation ( ); GO:0030239 myofibril assembly ( ); GO:0055002 striated muscle cell development ( ); GO:0051246 regulation of protein metabolic process ( ); GO:0010594 regulation of endothelial cell migration ( ); GO:0055010 ventricular cardiac muscle morphogenesis ( ); GO:0055001 muscle cell development ( ); GO:0051094 positive regulation of developmental process ( ); GO:0051016 barbed-end actin filament capping ( ); GO:0051693 actin filament capping ( ); GO:0055008 cardiac muscle tissue morphogenesis ( ); GO:0060415 muscle tissue morphogenesis ( ); GO:0031032 actomyosin structure organization ( ); GO:0030835 negative regulation of actin filament depolymerization ( ); GO:0030018 Z disc ( ); GO:0051128 regulation of cellular component organization ( ); GO:0030042 actin filament depolymerization ( ); GO:0030834 regulation of actin filament depolymerization ( ); GO:0007602 phototransduction ( ); GO:0030837 negative regulation of actin filament polymerization ( ); GO:0032272 negative regulation of protein polymerization ( ); GO:0051146 striated muscle cell differentiation ( ); GO:0031674 I band ( ); GO:0031333 negative regulation of protein complex assembly ( ); GO:0050908 detection of light stimulus involved in visual perception ( ); GO:0050962 detection of light stimulus involved in sensory perception ( ); GO:0009584 detection of visible light ( ); GO:0043542 endothelial cell migration ( ); ----------------GO-------------- GO:0030016 myofibril ( 0.000219607123961064 ); GO:0044449 contractile fiber part ( 0.000225355995196177 ); GO:0043292 contractile fiber ( 0.000249086031391523 ); GO:0033612 receptor serine/threonine kinase binding ( 0.000301613632936237 ); GO:0014706 striated muscle development ( 0.000615329318498954 ); GO:0010614 negative regulation of cardiac muscle hypertrophy ( 0.000904613475662286 ); GO:0010616 negative regulation of cardiac muscle adaptation ( 0.000904613475662286 ); GO:0014741 negative regulation of muscle hypertrophy ( 0.000904613475662286 ); GO:0055009 atrial cardiac muscle morphogenesis ( 0.000904613475662286 ); GO:0060045 positive regulation of cardiac muscle cell proliferation ( 0.000904613475662286 ); GO:0010613 positive regulation of cardiac muscle hypertrophy ( 0.00120599971594137 ); GO:0010615 positive regulation of cardiac muscle adaptation ( 0.00120599971594137 ); GO:0014742 positive regulation of muscle hypertrophy ( 0.00120599971594137 ); GO:0014744 positive regulation of muscle adaptation ( 0.00120599971594137 ); GO:0014745 negative regulation of muscle adaptation ( 0.00120599971594137 ); GO:0060343 trabecula formation ( 0.00120599971594137 ); GO:0060347 heart trabecula formation ( 0.00120599971594137 ); GO:0017025 TATA-binding protein binding ( 0.00120599971594137 ); GO:0007517 muscle development ( 0.00135507113779753 ); GO:0055015 ventricular cardiac muscle cell development ( 0.00150731018915273 ); GO:0030036 actin cytoskeleton organization ( 0.00164845242201023 ); GO:0010611 regulation of cardiac muscle hypertrophy ( 0.00180854491053573 ); GO:0010612 regulation of cardiac muscle adaptation ( 0.00180854491053573 ); GO:0014743 regulation of muscle hypertrophy ( 0.00180854491053573 ); GO:0014887 cardiac muscle adaptation ( 0.00180854491053573 ); GO:0014888 striated muscle adaptation ( 0.00180854491053573 ); GO:0014897 striated muscle hypertrophy ( 0.00180854491053573 ); GO:0014898 cardiac muscle hypertrophy ( 0.00180854491053573 ); GO:0015279 store-operated calcium channel activity ( 0.00180854491053573 ); GO:0030029 actin filament-based process ( 0.00191970307091327 ); GO:0043502 regulation of muscle adaptation ( 0.00210970389532639 ); GO:0055012 ventricular cardiac muscle cell differentiation ( 0.00210970389532639 ); GO:0060043 regulation of cardiac muscle cell proliferation ( 0.00210970389532639 ); GO:0043034 costamere ( 0.00210970389532639 ); GO:0014896 muscle hypertrophy ( 0.00241078715875942 ); GO:0055007 cardiac muscle cell differentiation ( 0.0027117947160662 ); GO:0055013 cardiac muscle cell development ( 0.0027117947160662 ); GO:0007512 adult heart development ( 0.00331358277321803 ); GO:0032924 activin receptor signaling pathway ( 0.00331358277321803 ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( 0.00361436330351461 ); GO:0014855 striated muscle cell proliferation ( 0.00361436330351461 ); GO:0043500 muscle adaptation ( 0.00361436330351461 ); GO:0045214 sarcomere organization ( 0.00361436330351461 ); GO:0060038 cardiac muscle cell proliferation ( 0.00361436330351461 ); GO:0010596 negative regulation of endothelial cell migration ( 0.00391506818858967 ); GO:0035051 cardiac cell differentiation ( 0.00391506818858967 ); GO:0032268 regulation of cellular protein metabolic process ( 0.00396124845892844 ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( 0.00421569744366346 ); GO:0002020 protease binding ( 0.00481672912467745 ); GO:0007010 cytoskeleton organization ( 0.00492527965680823 ); GO:0060389 pathway-restricted SMAD protein phosphorylation ( 0.00511713158104687 ); GO:0030239 myofibril assembly ( 0.00541745846827335 ); GO:0055002 striated muscle cell development ( 0.00541745846827335 ); GO:0051246 regulation of protein metabolic process ( 0.00545812279486251 ); GO:0010594 regulation of endothelial cell migration ( 0.00571770980156594 ); GO:0055010 ventricular cardiac muscle morphogenesis ( 0.00571770980156594 ); GO:0055001 muscle cell development ( 0.00601788559613137 ); GO:0051094 positive regulation of developmental process ( 0.00672082914558392 ); GO:0051016 barbed-end actin filament capping ( 0.0069179598994944 ); GO:0051693 actin filament capping ( 0.0069179598994944 ); GO:0055008 cardiac muscle tissue morphogenesis ( 0.0069179598994944 ); GO:0060415 muscle tissue morphogenesis ( 0.0069179598994944 ); GO:0031032 actomyosin structure organization ( 0.00721783369117057 ); GO:0030835 negative regulation of actin filament depolymerization ( 0.0075176320201179 ); GO:0030018 Z disc ( 0.0075176320201179 ); GO:0051128 regulation of cellular component organization ( 0.00755644066090075 ); GO:0030042 actin filament depolymerization ( 0.0081170023505952 ); GO:0030834 regulation of actin filament depolymerization ( 0.0081170023505952 ); GO:0007602 phototransduction ( 0.0087160710124411 ); GO:0030837 negative regulation of actin filament polymerization ( 0.0087160710124411 ); GO:0032272 negative regulation of protein polymerization ( 0.00901549225559073 ); GO:0051146 striated muscle cell differentiation ( 0.00931483812713418 ); GO:0031674 I band ( 0.00931483812713418 ); GO:0031333 negative regulation of protein complex assembly ( 0.00961410864225021 ); GO:0050908 detection of light stimulus involved in visual perception ( 0.00961410864225021 ); GO:0050962 detection of light stimulus involved in sensory perception ( 0.00961410864225021 ); GO:0009584 detection of visible light ( 0.00991330381611599 ); GO:0043542 endothelial cell migration ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- rhopathway ( 0.00361436330351461 ); myosinpathway ( 0.00601788559613137 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2033 ========================= ----------------C2-------------- ( 0.00931483812713418 ); ----------------C3-------------- ( 0.00991330381611599 ); ----------------C4-------------- module_249 ( 0.00631798586717336 ); module_489 ( 0.00901549225559073 ); ----------------C5-------------- ATP_DEPENDENT_RNA_HELICASE_ACTIVITY ( 0.00511713158104687 ); RNA_DEPENDENT_ATPASE_ACTIVITY ( 0.00541745846827335 ); RNA_HELICASE_ACTIVITY ( 0.00721783369117057 ); ATP_DEPENDENT_HELICASE_ACTIVITY ( 0.00781735490152924 ); PROTEIN_AMINO_ACID_N_LINKED_GLYCOSYLATION ( 0.0087160710124411 ); ----------------GOSLIM-------------- GO:0004758 serine C-palmitoyltransferase activity ( ); GO:0016454 C-palmitoyltransferase activity ( ); GO:0046527 glucosyltransferase activity ( ); GO:0016408 C-acyltransferase activity ( ); GO:0016409 palmitoyltransferase activity ( ); GO:0003824 catalytic activity ( ); GO:0004004 ATP-dependent RNA helicase activity ( ); GO:0008186 RNA-dependent ATPase activity ( ); GO:0003724 RNA helicase activity ( ); GO:0016769 transferase activity, transferring nitrogenous groups ( ); GO:0070011 peptidase activity, acting on L-amino acid peptides ( ); GO:0005789 endoplasmic reticulum membrane ( ); GO:0044432 endoplasmic reticulum part ( ); GO:0008233 peptidase activity ( ); GO:0042175 nuclear envelope-endoplasmic reticulum network ( ); ----------------GO-------------- GO:0004758 serine C-palmitoyltransferase activity ( 0.000904613475662286 ); GO:0016454 C-palmitoyltransferase activity ( 0.000904613475662286 ); GO:0046527 glucosyltransferase activity ( 0.00210970389532639 ); GO:0016408 C-acyltransferase activity ( 0.00361436330351461 ); GO:0016409 palmitoyltransferase activity ( 0.00361436330351461 ); GO:0003824 catalytic activity ( 0.00389207084963865 ); GO:0004004 ATP-dependent RNA helicase activity ( 0.00511713158104687 ); GO:0008186 RNA-dependent ATPase activity ( 0.00541745846827335 ); GO:0003724 RNA helicase activity ( 0.0075176320201179 ); GO:0016769 transferase activity, transferring nitrogenous groups ( 0.0087160710124411 ); GO:0070011 peptidase activity, acting on L-amino acid peptides ( 0.00929367504751739 ); GO:0005789 endoplasmic reticulum membrane ( 0.00943419847159822 ); GO:0044432 endoplasmic reticulum part ( 0.0096112244865944 ); GO:0008233 peptidase activity ( 0.00989762837633593 ); GO:0042175 nuclear envelope-endoplasmic reticulum network ( 0.00993370195306017 ); ----------------KEGG-------------- hsa00600 Sphingolipid metabolism ( 0.0117068935426602 ); hsa00510 N-Glycan biosynthesis ( 0.0126026725276674 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0350711246483632 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2639 ========================= ----------------C2-------------- BIOCARTA_LYM_PATHWAY ( 0.00331358277321803 ); REACTOME_CLASS_C3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS ( 0.00451625108395437 ); BIOCARTA_IL17_PATHWAY ( 0.00481672912467745 ); REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY ( 0.00571770980156594 ); REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC ( 0.00661801062989487 ); REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC ( 0.00841657438250376 ); ----------------C3-------------- ( 0.00107720876028592 ); ----------------C4-------------- ( ); ----------------C5-------------- LEUKOCYTE_MIGRATION ( 0.00391506818858967 ); INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHODIESTERASE_ACTIVITY ( 0.00391506818858967 ); PHOSPHOLIPASE_C_ACTIVITY ( 0.00451625108395437 ); DETECTION_OF_CHEMICAL_STIMULUS ( 0.00541745846827335 ); BONE_REMODELING ( 0.0087160710124411 ); TISSUE_REMODELING ( 0.00901549225559073 ); ----------------GOSLIM-------------- GO:0007635 chemosensory behavior ( ); GO:0032781 positive regulation of ATPase activity ( ); GO:0005513 detection of calcium ion ( ); GO:0043462 regulation of ATPase activity ( ); GO:0009593 detection of chemical stimulus ( ); GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( ); GO:0004435 phosphoinositide phospholipase C activity ( ); GO:0051924 regulation of calcium ion transport ( ); GO:0004629 phospholipase C activity ( ); GO:0051592 response to calcium ion ( ); ----------------GO-------------- GO:0007635 chemosensory behavior ( 0.00210970389532639 ); GO:0032781 positive regulation of ATPase activity ( 0.00241078715875942 ); GO:0005513 detection of calcium ion ( 0.0027117947160662 ); GO:0043462 regulation of ATPase activity ( 0.00421569744366346 ); GO:0009593 detection of chemical stimulus ( 0.0075176320201179 ); GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( 0.0075176320201179 ); GO:0004435 phosphoinositide phospholipase C activity ( 0.0075176320201179 ); GO:0051924 regulation of calcium ion transport ( 0.0087160710124411 ); GO:0004629 phospholipase C activity ( 0.00901549225559073 ); GO:0051592 response to calcium ion ( 0.00931483812713418 ); ----------------KEGG-------------- hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0152859508796624 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0152859508796624 ); hsa04640 Hematopoietic cell lineage ( 0.0250727099917203 ); hsa04540 Gap junction ( 0.0286113730795235 ); hsa04514 Cell adhesion molecules (CAMs) ( 0.0385795102055702 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2968 ========================= ----------------C2-------------- ( 0.00931483812713418 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0004034 aldose 1-epimerase activity ( 0.000540624745750649 ); GO:0070050 neuron maintenance ( 0.000540624745750649 ); GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives ( 0.000540624745750649 ); GO:0017040 ceramidase activity ( 0.000540624745750649 ); GO:0016854 racemase and epimerase activity ( 0.000540624745750649 ); GO:0005975 carbohydrate metabolic process ( 0.000540624745750649 ); GO:0006672 ceramide metabolic process ( 0.000540624745750649 ); ----------------GO-------------- GO:0004034 aldose 1-epimerase activity ( 0.000301613632936237 ); GO:0070050 neuron maintenance ( 0.000904613475662286 ); GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives ( 0.00210970389532639 ); GO:0017040 ceramidase activity ( 0.00241078715875942 ); GO:0016854 racemase and epimerase activity ( 0.00361436330351461 ); GO:0005975 carbohydrate metabolic process ( 0.00784512957680962 ); GO:0006672 ceramide metabolic process ( 0.00931483812713418 ); ----------------KEGG-------------- hsa00600 Sphingolipid metabolism ( 0.0117068935426602 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.0185572585514265 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3004 ========================= ----------------C2-------------- ( 0.00301272658247675 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0004996 thyroid-stimulating hormone receptor activity ( ); GO:0016500 protein-hormone receptor activity ( ); GO:0040018 positive regulation of multicellular organism growth ( ); GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( ); GO:0008344 adult locomotory behavior ( ); ----------------GO-------------- GO:0004996 thyroid-stimulating hormone receptor activity ( 0.000603151453075101 ); GO:0016500 protein-hormone receptor activity ( 0.00331358277321803 ); GO:0040018 positive regulation of multicellular organism growth ( 0.00571770980156594 ); GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway ( 0.00631798586717336 ); GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling ( 0.00631798586717336 ); GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway ( 0.00631798586717336 ); GO:0008344 adult locomotory behavior ( 0.00931483812713418 ); ----------------KEGG-------------- ( 0.0146901925632592 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3006 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_537 ( 0.00511713158104687 ); module_439 ( 0.00601788559613137 ); ----------------C5-------------- CELLULAR_CARBOHYDRATE_CATABOLIC_PROCESS ( 0.0069179598994944 ); CARBOHYDRATE_CATABOLIC_PROCESS ( 0.00721783369117057 ); ----------------GOSLIM-------------- GO:0016137 glycoside metabolic process ( ); GO:0016139 glycoside catabolic process ( ); GO:0008422 beta-glucosidase activity ( ); GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding ( ); GO:0043178 alcohol binding ( ); GO:0004565 beta-galactosidase activity ( ); GO:0003840 gamma-glutamyltransferase activity ( ); GO:0015925 galactosidase activity ( ); GO:0015926 glucosidase activity ( ); GO:0016755 transferase activity, transferring amino-acyl groups ( ); GO:0032312 regulation of ARF GTPase activity ( ); GO:0008060 ARF GTPase activator activity ( ); ----------------GO-------------- GO:0016137 glycoside metabolic process ( 0.000603151453075101 ); GO:0016139 glycoside catabolic process ( 0.000603151453075101 ); GO:0008422 beta-glucosidase activity ( 0.000904613475662286 ); GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding ( 0.000904613475662286 ); GO:0043178 alcohol binding ( 0.00120599971594137 ); GO:0004565 beta-galactosidase activity ( 0.00150731018915273 ); GO:0003840 gamma-glutamyltransferase activity ( 0.00180854491053573 ); GO:0015925 galactosidase activity ( 0.00180854491053573 ); GO:0015926 glucosidase activity ( 0.00241078715875942 ); GO:0016755 transferase activity, transferring amino-acyl groups ( 0.00511713158104687 ); GO:0032312 regulation of ARF GTPase activity ( 0.00781735490152924 ); GO:0008060 ARF GTPase activator activity ( 0.00781735490152924 ); ----------------KEGG-------------- hsa00460 Cyanoamino acid metabolism ( 0.0027117947160662 ); hsa00500 Starch and sucrose metabolism ( 0.0129011151232462 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3013 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0007400 neuroblast fate determination ( ); GO:0014016 neuroblast differentiation ( ); GO:0014017 neuroblast fate commitment ( ); GO:0060163 subpallium neuron fate commitment ( ); GO:0060165 regulation of timing of subpallium neuron differentiation ( ); GO:0009590 detection of gravity ( ); GO:0048865 stem cell fate commitment ( ); GO:0048867 stem cell fate determination ( ); GO:0060164 regulation of timing of neuron differentiation ( ); GO:0060166 olfactory pit development ( ); GO:0007423 sensory organ development ( ); GO:0009629 response to gravity ( ); GO:0021529 spinal cord oligodendrocyte cell differentiation ( ); GO:0021530 spinal cord oligodendrocyte cell fate specification ( ); GO:0021778 oligodendrocyte cell fate specification ( ); GO:0021779 oligodendrocyte cell fate commitment ( ); GO:0021780 glial cell fate specification ( ); GO:0021527 spinal cord association neuron differentiation ( ); GO:0040034 regulation of development, heterochronic ( ); GO:0045747 positive regulation of Notch signaling pathway ( ); GO:0048505 regulation of timing of cell differentiation ( ); GO:0021781 glial cell fate commitment ( ); GO:0043584 nose development ( ); GO:0008593 regulation of Notch signaling pathway ( ); GO:0021516 dorsal spinal cord development ( ); GO:0021544 subpallium development ( ); GO:0014003 oligodendrocyte development ( ); GO:0021782 glial cell development ( ); GO:0021987 cerebral cortex development ( ); GO:0048863 stem cell differentiation ( ); GO:0021515 cell differentiation in spinal cord ( ); GO:0048709 oligodendrocyte differentiation ( ); GO:0021954 central nervous system neuron development ( ); GO:0021543 pallium development ( ); GO:0021953 central nervous system neuron differentiation ( ); GO:0007405 neuroblast proliferation ( ); GO:0001708 cell fate specification ( ); GO:0021510 spinal cord development ( ); GO:0001709 cell fate determination ( ); GO:0048663 neuron fate commitment ( ); ----------------GO-------------- GO:0007400 neuroblast fate determination ( 0.000301613632936237 ); GO:0014016 neuroblast differentiation ( 0.000301613632936237 ); GO:0014017 neuroblast fate commitment ( 0.000301613632936237 ); GO:0060163 subpallium neuron fate commitment ( 0.000301613632936237 ); GO:0060165 regulation of timing of subpallium neuron differentiation ( 0.000301613632936237 ); GO:0009590 detection of gravity ( 0.000603151453075101 ); GO:0048865 stem cell fate commitment ( 0.000603151453075101 ); GO:0048867 stem cell fate determination ( 0.000603151453075101 ); GO:0060164 regulation of timing of neuron differentiation ( 0.000603151453075101 ); GO:0060166 olfactory pit development ( 0.000603151453075101 ); GO:0007423 sensory organ development ( 0.000830537377321579 ); GO:0009629 response to gravity ( 0.000904613475662286 ); GO:0021529 spinal cord oligodendrocyte cell differentiation ( 0.000904613475662286 ); GO:0021530 spinal cord oligodendrocyte cell fate specification ( 0.000904613475662286 ); GO:0021778 oligodendrocyte cell fate specification ( 0.000904613475662286 ); GO:0021779 oligodendrocyte cell fate commitment ( 0.000904613475662286 ); GO:0021780 glial cell fate specification ( 0.000904613475662286 ); GO:0021527 spinal cord association neuron differentiation ( 0.00120599971594137 ); GO:0040034 regulation of development, heterochronic ( 0.00120599971594137 ); GO:0045747 positive regulation of Notch signaling pathway ( 0.00120599971594137 ); GO:0048505 regulation of timing of cell differentiation ( 0.00120599971594137 ); GO:0021781 glial cell fate commitment ( 0.00180854491053573 ); GO:0043584 nose development ( 0.00180854491053573 ); GO:0008593 regulation of Notch signaling pathway ( 0.00210970389532639 ); GO:0021516 dorsal spinal cord development ( 0.00241078715875942 ); GO:0021544 subpallium development ( 0.0027117947160662 ); GO:0014003 oligodendrocyte development ( 0.00331358277321803 ); GO:0021782 glial cell development ( 0.00481672912467745 ); GO:0021987 cerebral cortex development ( 0.00511713158104687 ); GO:0048863 stem cell differentiation ( 0.00511713158104687 ); GO:0021515 cell differentiation in spinal cord ( 0.00541745846827335 ); GO:0048709 oligodendrocyte differentiation ( 0.00541745846827335 ); GO:0021954 central nervous system neuron development ( 0.00571770980156594 ); GO:0021543 pallium development ( 0.00661801062989487 ); GO:0021953 central nervous system neuron differentiation ( 0.00661801062989487 ); GO:0007405 neuroblast proliferation ( 0.0069179598994944 ); GO:0001708 cell fate specification ( 0.00721783369117057 ); GO:0021510 spinal cord development ( 0.00841657438250376 ); GO:0001709 cell fate determination ( 0.0087160710124411 ); GO:0048663 neuron fate commitment ( 0.00931483812713418 ); ----------------KEGG-------------- hsa02010 ABC transporters - General ( 0.0131994825443676 ); hsa04530 Tight junction ( 0.0391632063235058 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3020 ========================= ----------------C2-------------- ( 0.00931483812713418 ); ----------------C3-------------- ( ); ----------------C4-------------- module_571 ( 0.00451625108395437 ); module_349 ( 0.00511713158104687 ); GNF2_SPRR1B ( 0.00661801062989487 ); ----------------C5-------------- CORNIFIED_ENVELOPE ( 0.00391506818858967 ); S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY ( 0.0069179598994944 ); ----------------GOSLIM-------------- GO:0006521 regulation of amino acid metabolic process ( ); GO:0031335 regulation of sulfur amino acid metabolic process ( ); GO:0042762 regulation of sulfur metabolic process ( ); GO:0050666 regulation of homocysteine metabolic process ( ); GO:0050667 homocysteine metabolic process ( ); GO:0047150 betaine-homocysteine S-methyltransferase activity ( ); GO:0008898 homocysteine S-methyltransferase activity ( ); GO:0007017 microtubule-based process ( ); GO:0033238 regulation of cellular amine metabolic process ( ); GO:0008172 S-methyltransferase activity ( ); GO:0005874 microtubule ( ); GO:0009086 methionine biosynthetic process ( ); GO:0006555 methionine metabolic process ( ); GO:0000097 sulfur amino acid biosynthetic process ( ); GO:0009067 aspartate family amino acid biosynthetic process ( ); GO:0006479 protein amino acid methylation ( ); GO:0008213 protein amino acid alkylation ( ); GO:0000096 sulfur amino acid metabolic process ( ); GO:0009066 aspartate family amino acid metabolic process ( ); GO:0015630 microtubule cytoskeleton ( ); GO:0051171 regulation of nitrogen compound metabolic process ( ); GO:0005198 structural molecule activity ( ); ----------------GO-------------- GO:0006521 regulation of amino acid metabolic process ( 0.000301613632936237 ); GO:0031335 regulation of sulfur amino acid metabolic process ( 0.000301613632936237 ); GO:0042762 regulation of sulfur metabolic process ( 0.000301613632936237 ); GO:0050666 regulation of homocysteine metabolic process ( 0.000301613632936237 ); GO:0050667 homocysteine metabolic process ( 0.000603151453075101 ); GO:0047150 betaine-homocysteine S-methyltransferase activity ( 0.000603151453075101 ); GO:0008898 homocysteine S-methyltransferase activity ( 0.000904613475662286 ); GO:0007017 microtubule-based process ( 0.00149827070328985 ); GO:0033238 regulation of cellular amine metabolic process ( 0.00180854491053573 ); GO:0008172 S-methyltransferase activity ( 0.00180854491053573 ); GO:0005874 microtubule ( 0.00185407914022061 ); GO:0009086 methionine biosynthetic process ( 0.0027117947160662 ); GO:0006555 methionine metabolic process ( 0.00361436330351461 ); GO:0000097 sulfur amino acid biosynthetic process ( 0.00451625108395437 ); GO:0009067 aspartate family amino acid biosynthetic process ( 0.00451625108395437 ); GO:0006479 protein amino acid methylation ( 0.00571770980156594 ); GO:0008213 protein amino acid alkylation ( 0.00571770980156594 ); GO:0000096 sulfur amino acid metabolic process ( 0.00631798586717336 ); GO:0009066 aspartate family amino acid metabolic process ( 0.00631798586717336 ); GO:0015630 microtubule cytoskeleton ( 0.00733540383113857 ); GO:0051171 regulation of nitrogen compound metabolic process ( 0.0075176320201179 ); GO:0005198 structural molecule activity ( 0.00996983612662705 ); ----------------KEGG-------------- hsa00271 Methionine metabolism ( 0.00631798586717336 ); hsa00260 Glycine, serine and threonine metabolism ( 0.0123041547424798 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.0152859508796624 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.0152859508796624 ); hsa04540 Gap junction ( 0.0286113730795235 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3053 ========================= ----------------C2-------------- ( 0.00391506818858967 ); ----------------C3-------------- V$NRF2_01 ( 0.00102781067353379 ); V$PXR_Q2 ( 0.00139729614762568 ); ----------------C4-------------- module_423 ( 0.00210970389532639 ); module_478 ( 0.00571770980156594 ); GNF2_BUB1 ( 0.0075176320201179 ); GNF2_SMC2L1 ( 0.00901549225559073 ); ----------------C5-------------- ( 0.0027117947160662 ); ----------------GOSLIM-------------- GO:0008475 procollagen-lysine 5-dioxygenase activity ( ); GO:0030867 rough endoplasmic reticulum membrane ( ); GO:0005791 rough endoplasmic reticulum ( ); GO:0016538 cyclin-dependent protein kinase regulator activity ( ); GO:0031418 L-ascorbic acid binding ( ); GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ( ); ----------------GO-------------- GO:0008475 procollagen-lysine 5-dioxygenase activity ( 0.000904613475662286 ); GO:0030867 rough endoplasmic reticulum membrane ( 0.00301272658247675 ); GO:0005791 rough endoplasmic reticulum ( 0.00451625108395437 ); GO:0016538 cyclin-dependent protein kinase regulator activity ( 0.00451625108395437 ); GO:0031418 L-ascorbic acid binding ( 0.00601788559613137 ); GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ( 0.0069179598994944 ); ----------------KEGG-------------- hsa00310 Lysine degradation ( 0.0149881092556912 ); hsa05222 Small cell lung cancer ( 0.0256632320228238 ); ----------------CARTA-------------- ( 0.00451625108395437 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3065 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- EPITHELIAL_CELL_DIFFERENTIATION ( 0.00301272658247675 ); MORPHOGENESIS_OF_AN_EPITHELIUM ( 0.00481672912467745 ); ----------------GOSLIM-------------- GO:0007638 mechanosensory behavior ( ); GO:0009612 response to mechanical stimulus ( ); GO:0007272 ensheathment of neurons ( ); GO:0008366 axon ensheathment ( ); ----------------GO-------------- GO:0007638 mechanosensory behavior ( 0.00241078715875942 ); GO:0009612 response to mechanical stimulus ( 0.0087160710124411 ); GO:0007272 ensheathment of neurons ( 0.00901549225559073 ); GO:0008366 axon ensheathment ( 0.00901549225559073 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3094 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00571770980156594 ); ----------------C5-------------- ACUTE_INFLAMMATORY_RESPONSE ( 0.00331358277321803 ); REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS ( 0.00451625108395437 ); REGULATION_OF_ENDOCYTOSIS ( 0.00451625108395437 ); PHAGOCYTOSIS ( 0.00511713158104687 ); REGULATION_OF_DEFENSE_RESPONSE ( 0.00601788559613137 ); POSITIVE_REGULATION_OF_TRANSPORT ( 0.0069179598994944 ); BONE_REMODELING ( 0.0087160710124411 ); TISSUE_REMODELING ( 0.00901549225559073 ); NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS ( 0.00931483812713418 ); ----------------GOSLIM-------------- GO:0030292 protein tyrosine kinase inhibitor activity ( ); GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity ( ); GO:0045780 positive regulation of bone resorption ( ); GO:0006907 pinocytosis ( ); GO:0031100 organ regeneration ( ); GO:0046627 negative regulation of insulin receptor signaling pathway ( ); GO:0046626 regulation of insulin receptor signaling pathway ( ); GO:0000160 two-component signal transduction system (phosphorelay) ( ); GO:0045124 regulation of bone resorption ( ); GO:0050766 positive regulation of phagocytosis ( ); GO:0032846 positive regulation of homeostatic process ( ); GO:0032869 cellular response to insulin stimulus ( ); GO:0050764 regulation of phagocytosis ( ); GO:0000155 two-component sensor activity ( ); GO:0004673 protein histidine kinase activity ( ); GO:0032870 cellular response to hormone stimulus ( ); GO:0021987 cerebral cortex development ( ); GO:0045453 bone resorption ( ); GO:0016775 phosphotransferase activity, nitrogenous group as acceptor ( ); GO:0032868 response to insulin stimulus ( ); GO:0045807 positive regulation of endocytosis ( ); GO:0021543 pallium development ( ); GO:0046852 positive regulation of bone remodeling ( ); GO:0031099 regeneration ( ); GO:0034105 positive regulation of tissue remodeling ( ); GO:0008584 male gonad development ( ); GO:0006953 acute-phase response ( ); GO:0008286 insulin receptor signaling pathway ( ); GO:0004869 cysteine-type endopeptidase inhibitor activity ( ); GO:0005044 scavenger receptor activity ( ); ----------------GO-------------- GO:0030292 protein tyrosine kinase inhibitor activity ( 0.000301613632936237 ); GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity ( 0.000301613632936237 ); GO:0045780 positive regulation of bone resorption ( 0.000904613475662286 ); GO:0006907 pinocytosis ( 0.00150731018915273 ); GO:0031100 organ regeneration ( 0.00150731018915273 ); GO:0046627 negative regulation of insulin receptor signaling pathway ( 0.00180854491053573 ); GO:0046626 regulation of insulin receptor signaling pathway ( 0.00210970389532639 ); GO:0000160 two-component signal transduction system (phosphorelay) ( 0.0027117947160662 ); GO:0045124 regulation of bone resorption ( 0.0027117947160662 ); GO:0050766 positive regulation of phagocytosis ( 0.0027117947160662 ); GO:0032846 positive regulation of homeostatic process ( 0.00301272658247675 ); GO:0032869 cellular response to insulin stimulus ( 0.00301272658247675 ); GO:0050764 regulation of phagocytosis ( 0.00331358277321803 ); GO:0000155 two-component sensor activity ( 0.00391506818858967 ); GO:0004673 protein histidine kinase activity ( 0.00391506818858967 ); GO:0032870 cellular response to hormone stimulus ( 0.00451625108395437 ); GO:0021987 cerebral cortex development ( 0.00511713158104687 ); GO:0045453 bone resorption ( 0.00511713158104687 ); GO:0016775 phosphotransferase activity, nitrogenous group as acceptor ( 0.00511713158104687 ); GO:0032868 response to insulin stimulus ( 0.00571770980156594 ); GO:0045807 positive regulation of endocytosis ( 0.00631798586717336 ); GO:0021543 pallium development ( 0.00661801062989487 ); GO:0046852 positive regulation of bone remodeling ( 0.00661801062989487 ); GO:0031099 regeneration ( 0.0069179598994944 ); GO:0034105 positive regulation of tissue remodeling ( 0.0069179598994944 ); GO:0008584 male gonad development ( 0.00841657438250376 ); GO:0006953 acute-phase response ( 0.00901549225559073 ); GO:0008286 insulin receptor signaling pathway ( 0.00961410864225021 ); GO:0004869 cysteine-type endopeptidase inhibitor activity ( 0.00991330381611599 ); GO:0005044 scavenger receptor activity ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3112 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0031082 BLOC complex ( ); GO:0031083 BLOC-1 complex ( ); GO:0033363 secretory granule organization ( ); GO:0060155 platelet dense granule organization ( ); GO:0032438 melanosome organization ( ); GO:0048753 pigment granule organization ( ); GO:0043015 gamma-tubulin binding ( ); GO:0000930 gamma-tubulin complex ( ); GO:0033059 cellular pigmentation ( ); GO:0042802 identical protein binding ( ); GO:0044450 microtubule organizing center part ( ); ----------------GO-------------- GO:0031082 BLOC complex ( 0.000904613475662286 ); GO:0031083 BLOC-1 complex ( 0.000904613475662286 ); GO:0033363 secretory granule organization ( 0.00120599971594137 ); GO:0060155 platelet dense granule organization ( 0.00120599971594137 ); GO:0032438 melanosome organization ( 0.00210970389532639 ); GO:0048753 pigment granule organization ( 0.00241078715875942 ); GO:0043015 gamma-tubulin binding ( 0.00241078715875942 ); GO:0000930 gamma-tubulin complex ( 0.00301272658247675 ); GO:0033059 cellular pigmentation ( 0.00451625108395437 ); GO:0042802 identical protein binding ( 0.00746133504074856 ); GO:0044450 microtubule organizing center part ( 0.00961410864225021 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3138 ========================= ----------------C2-------------- ( 0.00361436330351461 ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00421569744366346 ); ----------------C5-------------- LYSOSOMAL_MEMBRANE ( 0.00301272658247675 ); VACUOLAR_MEMBRANE ( 0.00331358277321803 ); LYSOSOME_ORGANIZATION_AND_BIOGENESIS ( 0.00331358277321803 ); COFACTOR_TRANSPORT ( 0.00331358277321803 ); VACUOLE_ORGANIZATION_AND_BIOGENESIS ( 0.00361436330351461 ); VITAMIN_BINDING ( 0.00361436330351461 ); VACUOLAR_PART ( 0.00391506818858967 ); VITAMIN_TRANSPORT ( 0.00391506818858967 ); CALMODULIN_BINDING ( 0.0075176320201179 ); SYNAPSE ( 0.0081170023505952 ); RECEPTOR_MEDIATED_ENDOCYTOSIS ( 0.00991330381611599 ); ----------------GOSLIM-------------- GO:0046655 folic acid metabolic process ( 0.00739824416105136 ); GO:0001917 photoreceptor inner segment ( 0.00739824416105136 ); GO:0015884 folic acid transport ( 0.00739824416105136 ); GO:0050957 equilibrioception ( 0.00739824416105136 ); GO:0001750 photoreceptor outer segment ( 0.00739824416105136 ); GO:0005542 folic acid binding ( 0.00739824416105136 ); GO:0051181 cofactor transport ( 0.00739824416105136 ); GO:0000146 microfilament motor activity ( 0.00739824416105136 ); GO:0006760 folic acid and derivative metabolic process ( 0.00739824416105136 ); GO:0042558 pteridine and derivative metabolic process ( 0.00739824416105136 ); GO:0051180 vitamin transport ( 0.00739824416105136 ); GO:0007040 lysosome organization ( 0.00739824416105136 ); GO:0007033 vacuole organization ( 0.00739824416105136 ); GO:0030048 actin filament-based movement ( 0.00739824416105136 ); GO:0031513 nonmotile primary cilium ( 0.00739824416105136 ); GO:0006752 group transfer coenzyme metabolic process ( 0.00739824416105136 ); GO:0050885 neuromuscular process controlling balance ( 0.00739824416105136 ); ----------------GO-------------- GO:0046655 folic acid metabolic process ( 0.000603151453075101 ); GO:0001917 photoreceptor inner segment ( 0.00120599971594137 ); GO:0015884 folic acid transport ( 0.00180854491053573 ); GO:0050957 equilibrioception ( 0.00241078715875942 ); GO:0001750 photoreceptor outer segment ( 0.00301272658247675 ); GO:0005542 folic acid binding ( 0.00361436330351461 ); GO:0051181 cofactor transport ( 0.00391506818858967 ); GO:0000146 microfilament motor activity ( 0.00421569744366346 ); GO:0006760 folic acid and derivative metabolic process ( 0.00451625108395437 ); GO:0042558 pteridine and derivative metabolic process ( 0.00451625108395437 ); GO:0051180 vitamin transport ( 0.00541745846827335 ); GO:0007040 lysosome organization ( 0.00601788559613137 ); GO:0007033 vacuole organization ( 0.00661801062989487 ); GO:0030048 actin filament-based movement ( 0.00661801062989487 ); GO:0031513 nonmotile primary cilium ( 0.00661801062989487 ); GO:0006752 group transfer coenzyme metabolic process ( 0.0075176320201179 ); GO:0050885 neuromuscular process controlling balance ( 0.00781735490152924 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3139 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00361436330351461 ); ----------------C4-------------- module_15 ( 0.00429582717179565 ); module_219 ( 0.00781735490152924 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0021794 thalamus development ( ); GO:0047429 nucleoside-triphosphate diphosphatase activity ( ); GO:0035267 NuA4 histone acetyltransferase complex ( ); GO:0043189 H4/H2A histone acetyltransferase complex ( ); GO:0030901 midbrain development ( ); GO:0000123 histone acetyltransferase complex ( ); GO:0040007 growth ( ); GO:0016573 histone acetylation ( ); GO:0006473 protein amino acid acetylation ( ); GO:0021536 diencephalon development ( ); GO:0050681 androgen receptor binding ( ); GO:0004402 histone acetyltransferase activity ( ); GO:0004468 lysine N-acetyltransferase activity ( ); GO:0043543 protein amino acid acylation ( ); GO:0009791 post-embryonic development ( ); ----------------GO-------------- GO:0021794 thalamus development ( 0.000301613632936237 ); GO:0047429 nucleoside-triphosphate diphosphatase activity ( 0.00120599971594137 ); GO:0035267 NuA4 histone acetyltransferase complex ( 0.00180854491053573 ); GO:0043189 H4/H2A histone acetyltransferase complex ( 0.00210970389532639 ); GO:0030901 midbrain development ( 0.00301272658247675 ); GO:0000123 histone acetyltransferase complex ( 0.00331358277321803 ); GO:0040007 growth ( 0.00373019351444407 ); GO:0016573 histone acetylation ( 0.00421569744366346 ); GO:0006473 protein amino acid acetylation ( 0.00571770980156594 ); GO:0021536 diencephalon development ( 0.00571770980156594 ); GO:0050681 androgen receptor binding ( 0.00721783369117057 ); GO:0004402 histone acetyltransferase activity ( 0.0075176320201179 ); GO:0004468 lysine N-acetyltransferase activity ( 0.0075176320201179 ); GO:0043543 protein amino acid acylation ( 0.00781735490152924 ); GO:0009791 post-embryonic development ( 0.00901549225559073 ); ----------------KEGG-------------- hsa00983 Drug metabolism - other enzymes ( 0.0131994825443676 ); hsa05221 Acute myeloid leukemia ( 0.0167740335021956 ); hsa00240 Pyrimidine metabolism ( 0.0271382331746226 ); hsa00230 Purine metabolism ( 0.0435315214848334 ); hsa04630 Jak-STAT signaling pathway ( 0.0452742072258897 ); ----------------CARTA-------------- ( 0.00481672912467745 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.00511713158104687 ); ============================ group3144 ========================= ----------------C2-------------- REACTOME_TRANSFORMATION_OF_LANOSTEROL_TO_CHOLESTEROL ( 0.00301272658247675 ); KEGG_STEROID_BIOSYNTHESIS ( 0.00511713158104687 ); REACTOME_DUAL_INCISION_REACTION_IN_GG_NER ( 0.00601788559613137 ); REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE ( 0.00601788559613137 ); REACTOME_CHOLESTEROL_BIOSYNTHESIS ( 0.00631798586717336 ); REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_TERMINATION ( 0.00631798586717336 ); REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION ( 0.00721783369117057 ); REACTOME_RNA_POL_II_CTD_PHOSPHORYLATION_AND_INTERACTION_WITH_CE ( 0.00781735490152924 ); REACTOME_DUAL_INCISION_REACTION_IN_TC_NER ( 0.00841657438250376 ); REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX ( 0.00961410864225021 ); REACTOME_MRNA_PROCESSING ( 0.00961410864225021 ); REACTOME_GLOBAL_GENOMIC_NER ( 0.00991330381611599 ); REACTOME_RNA_POLYMERASE_I_CHAIN_ELONGATION ( 0.00991330381611599 ); ----------------C3-------------- ( ); ----------------C4-------------- module_93 ( 0.00119248916371707 ); module_500 ( 0.0087160710124411 ); ----------------C5-------------- RESPONSE_TO_OXIDATIVE_STRESS ( 7.46230245788897e-05 ); EPIDERMIS_DEVELOPMENT ( 0.000181425126002912 ); ECTODERM_DEVELOPMENT ( 0.000231178351516181 ); ORGAN_DEVELOPMENT ( 0.000429755417891114 ); TISSUE_DEVELOPMENT ( 0.000693585995054765 ); SYSTEM_DEVELOPMENT ( 0.0014061591594779 ); ANATOMICAL_STRUCTURE_DEVELOPMENT ( 0.0022523822523151 ); MULTICELLULAR_ORGANISMAL_DEVELOPMENT ( 0.00246681542435559 ); RESPONSE_TO_CHEMICAL_STIMULUS ( 0.00328803281942234 ); REGULATION_OF_APOPTOSIS ( 0.00393784495917129 ); REGULATION_OF_PROGRAMMED_CELL_DEATH ( 0.00396124845892844 ); TISSUE_MORPHOGENESIS ( 0.00421569744366346 ); NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY ( 0.00421569744366346 ); NUCLEOTIDE_EXCISION_REPAIR ( 0.00601788559613137 ); APOPTOSIS_GO ( 0.00624737281547936 ); PROGRAMMED_CELL_DEATH ( 0.00627648737278352 ); REGULATION_OF_DEVELOPMENTAL_PROCESS ( 0.00648207013536807 ); DNA_CATABOLIC_PROCESS ( 0.0069179598994944 ); STEROID_BIOSYNTHETIC_PROCESS ( 0.0069179598994944 ); OXIDOREDUCTASE_ACTIVITY__ACTING_ON_THE_CH_CH_GROUP_OF_DONORS ( 0.0069179598994944 ); DNA_HELICASE_ACTIVITY ( 0.00721783369117057 ); ANTIGEN_BINDING ( 0.00721783369117057 ); RESPONSE_TO_UV ( 0.0075176320201179 ); RESPONSE_TO_STRESS ( 0.0086395651024353 ); ----------------GOSLIM-------------- GO:0006979 response to oxidative stress ( 0.0024148352832836 ); GO:0006950 response to stress ( 0.0053602983460414 ); GO:0050614 delta24-sterol reductase activity ( 0.0062836693041719 ); GO:0043526 neuroprotection ( 0.00661393583624659 ); GO:0042221 response to chemical stimulus ( 0.0079925315459243 ); GO:0035315 hair cell differentiation ( 0.0024148352832836 ); GO:0043139 5'-3' DNA helicase activity ( 0.0053602983460414 ); GO:0006915 apoptosis ( 0.0062836693041719 ); GO:0012501 programmed cell death ( 0.00661393583624659 ); GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex ( 0.0079925315459243 ); GO:0008219 cell death ( 0.0024148352832836 ); GO:0016265 death ( 0.0053602983460414 ); GO:0006283 transcription-coupled nucleotide-excision repair ( 0.0062836693041719 ); GO:0031639 plasminogen activation ( 0.00661393583624659 ); GO:0033683 nucleotide-excision repair, DNA incision ( 0.0079925315459243 ); GO:0005675 holo TFIIH complex ( 0.0024148352832836 ); GO:0044248 cellular catabolic process ( 0.0053602983460414 ); GO:0000737 DNA catabolic process, endonucleolytic ( 0.0062836693041719 ); GO:0042605 peptide antigen binding ( 0.00661393583624659 ); GO:0051920 peroxiredoxin activity ( 0.0079925315459243 ); GO:0009650 UV protection ( 0.0024148352832836 ); GO:0031638 zymogen activation ( 0.0053602983460414 ); GO:0042987 amyloid precursor protein catabolic process ( 0.0062836693041719 ); GO:0009056 catabolic process ( 0.00661393583624659 ); GO:0030539 male genitalia development ( 0.0079925315459243 ); GO:0043154 negative regulation of caspase activity ( 0.0024148352832836 ); GO:0009888 tissue development ( 0.0053602983460414 ); GO:0010466 negative regulation of peptidase activity ( 0.0062836693041719 ); GO:0048806 genitalia development ( 0.00661393583624659 ); GO:0050896 response to stimulus ( 0.0079925315459243 ); GO:0042744 hydrogen peroxide catabolic process ( 0.0024148352832836 ); GO:0042982 amyloid precursor protein metabolic process ( 0.0053602983460414 ); GO:0006516 glycoprotein catabolic process ( 0.0062836693041719 ); GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor ( 0.00661393583624659 ); GO:0000718 nucleotide-excision repair, DNA damage removal ( 0.0079925315459243 ); GO:0004003 ATP-dependent DNA helicase activity ( 0.0024148352832836 ); GO:0042743 hydrogen peroxide metabolic process ( 0.0053602983460414 ); GO:0003823 antigen binding ( 0.0062836693041719 ); GO:0032502 developmental process ( 0.00661393583624659 ); GO:0042542 response to hydrogen peroxide ( 0.0079925315459243 ); GO:0006695 cholesterol biosynthetic process ( 0.0024148352832836 ); GO:0051346 negative regulation of hydrolase activity ( 0.0053602983460414 ); GO:0004601 peroxidase activity ( 0.0062836693041719 ); GO:0016684 oxidoreductase activity, acting on peroxide as acceptor ( 0.00661393583624659 ); GO:0005789 endoplasmic reticulum membrane ( 0.0079925315459243 ); GO:0044432 endoplasmic reticulum part ( 0.0024148352832836 ); GO:0042175 nuclear envelope-endoplasmic reticulum network ( 0.0053602983460414 ); ----------------GO-------------- GO:0006979 response to oxidative stress ( 3.16236377710705e-06 ); GO:0006950 response to stress ( 0.000295095199874936 ); GO:0050614 delta24-sterol reductase activity ( 0.000301613632936237 ); GO:0043526 neuroprotection ( 0.000603151453075101 ); GO:0042221 response to chemical stimulus ( 0.000880664113209897 ); GO:0035315 hair cell differentiation ( 0.000904613475662286 ); GO:0043139 5'-3' DNA helicase activity ( 0.000904613475662286 ); GO:0006915 apoptosis ( 0.00133983754853577 ); GO:0012501 programmed cell death ( 0.00137748306379472 ); GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex ( 0.00150731018915273 ); GO:0008219 cell death ( 0.0016335271057115 ); GO:0016265 death ( 0.00166015254509342 ); GO:0006283 transcription-coupled nucleotide-excision repair ( 0.00180854491053573 ); GO:0031639 plasminogen activation ( 0.00180854491053573 ); GO:0033683 nucleotide-excision repair, DNA incision ( 0.00180854491053573 ); GO:0005675 holo TFIIH complex ( 0.00180854491053573 ); GO:0044248 cellular catabolic process ( 0.00207484930851527 ); GO:0000737 DNA catabolic process, endonucleolytic ( 0.00210970389532639 ); GO:0042605 peptide antigen binding ( 0.00210970389532639 ); GO:0051920 peroxiredoxin activity ( 0.00210970389532639 ); GO:0009650 UV protection ( 0.00241078715875942 ); GO:0031638 zymogen activation ( 0.00241078715875942 ); GO:0042987 amyloid precursor protein catabolic process ( 0.0027117947160662 ); GO:0009056 catabolic process ( 0.00298017128416613 ); GO:0030539 male genitalia development ( 0.00301272658247675 ); GO:0043154 negative regulation of caspase activity ( 0.00301272658247675 ); GO:0009888 tissue development ( 0.00391450760737765 ); GO:0010466 negative regulation of peptidase activity ( 0.00391506818858967 ); GO:0048806 genitalia development ( 0.00391506818858967 ); GO:0050896 response to stimulus ( 0.00427048163404294 ); GO:0042744 hydrogen peroxide catabolic process ( 0.00451625108395437 ); GO:0042982 amyloid precursor protein metabolic process ( 0.00451625108395437 ); GO:0006516 glycoprotein catabolic process ( 0.00511713158104687 ); GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor ( 0.00571770980156594 ); GO:0000718 nucleotide-excision repair, DNA damage removal ( 0.00631798586717336 ); GO:0004003 ATP-dependent DNA helicase activity ( 0.00661801062989487 ); GO:0042743 hydrogen peroxide metabolic process ( 0.00721783369117057 ); GO:0003823 antigen binding ( 0.00781735490152924 ); GO:0032502 developmental process ( 0.00786332501361865 ); GO:0042542 response to hydrogen peroxide ( 0.00841657438250376 ); GO:0006695 cholesterol biosynthetic process ( 0.00901549225559073 ); GO:0051346 negative regulation of hydrolase activity ( 0.00931483812713418 ); GO:0004601 peroxidase activity ( 0.00931483812713418 ); GO:0016684 oxidoreductase activity, acting on peroxide as acceptor ( 0.00931483812713418 ); GO:0005789 endoplasmic reticulum membrane ( 0.00943419847159822 ); GO:0044432 endoplasmic reticulum part ( 0.0096112244865944 ); GO:0042175 nuclear envelope-endoplasmic reticulum network ( 0.00993370195306017 ); ----------------KEGG-------------- hsa00100 Biosynthesis of steroids ( 0.00721783369117057 ); hsa03420 Nucleotide excision repair ( 0.0129011151232462 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ELAVL1_CLIP-SEQ_(Kishore_2011) ( 0.00320280799570938 ); ELAVL1_PAR-CLIP_(Kishore_2011) ( 0.00807315263509296 ); AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0230548851828512 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0255384091866049 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0295271668786711 ); ----------------immu-------------- ( 0.00800769246789811 ); ----------------ARE-------------- ( ); ============================ group3160 ========================= ----------------C2-------------- ( 0.00901549225559073 ); ----------------C3-------------- V$PTF1BETA_Q6 ( 0.00114054752067503 ); GGCAGAC,MIR-346 ( 0.00961410864225021 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0021798 forebrain dorsal/ventral pattern formation ( ); GO:0021871 forebrain regionalization ( ); GO:0030878 thyroid gland development ( ); GO:0007492 endoderm development ( ); GO:0030426 growth cone ( ); GO:0005891 voltage-gated calcium channel complex ( ); GO:0005158 insulin receptor binding ( ); GO:0030427 site of polarized growth ( ); GO:0034704 calcium channel complex ( ); GO:0005245 voltage-gated calcium channel activity ( ); ----------------GO-------------- GO:0021798 forebrain dorsal/ventral pattern formation ( 0.000603151453075101 ); GO:0021871 forebrain regionalization ( 0.00180854491053573 ); GO:0030878 thyroid gland development ( 0.00301272658247675 ); GO:0007492 endoderm development ( 0.00361436330351461 ); GO:0030426 growth cone ( 0.00601788559613137 ); GO:0005891 voltage-gated calcium channel complex ( 0.00631798586717336 ); GO:0005158 insulin receptor binding ( 0.00631798586717336 ); GO:0030427 site of polarized growth ( 0.00661801062989487 ); GO:0034704 calcium channel complex ( 0.00721783369117057 ); GO:0005245 voltage-gated calcium channel activity ( 0.00721783369117057 ); ----------------KEGG-------------- ( 0.0446936062247032 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3165 ========================= ----------------C2-------------- REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX ( 0.00331358277321803 ); REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PREREPLICATIVE_COMPLEX ( 0.00361436330351461 ); REACTOME_G1_PHASE ( 0.00481672912467745 ); REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S ( 0.00631798586717336 ); REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION ( 0.00961410864225021 ); ----------------C3-------------- V$ISRE_01 ( 0.00106475307379579 ); V$ELF1_Q6 ( 0.00111500006822516 ); V$IRF7_01 ( 0.00144015138724121 ); RGAANNTTC_V$HSF1_01 ( 0.00370745276761774 ); GTAGGCA,MIR-189 ( 0.00661801062989487 ); MGGAAGTG_V$GABP_B ( 0.00915412895605736 ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.0087160710124411 ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( ); ----------------KEGG-------------- hsa05219 Bladder cancer ( 0.0126026725276674 ); hsa05223 Non-small cell lung cancer ( 0.016179025492135 ); hsa05214 Glioma ( 0.0191510676438879 ); hsa05218 Melanoma ( 0.0212270422708472 ); hsa05212 Pancreatic cancer ( 0.0215233109494052 ); hsa05220 Chronic myeloid leukemia ( 0.0221156241134317 ); hsa05222 Small cell lung cancer ( 0.0256632320228238 ); hsa05215 Prostate cancer ( 0.0262534559535107 ); hsa04110 Cell cycle ( 0.033312935077988 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3202 ========================= ----------------C2-------------- KEGG_PHENYLALANINE_METABOLISM ( 0.00511713158104687 ); KEGG_BETA_ALANINE_METABOLISM ( 0.00661801062989487 ); KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM ( 0.00931483812713418 ); REACTOME_MRNA_PROCESSING ( 0.00961410864225021 ); ----------------C3-------------- ( 0.00841657438250376 ); ----------------C4-------------- ( ); ----------------C5-------------- PROTEIN_STABILIZATION ( 0.00331358277321803 ); SINGLE_STRANDED_RNA_BINDING ( 0.00361436330351461 ); DOUBLE_STRANDED_RNA_BINDING ( 0.00511713158104687 ); REGULATION_OF_PROTEIN_STABILITY ( 0.00571770980156594 ); REGULATION_OF_BIOLOGICAL_QUALITY ( 0.00581831220992174 ); RESPONSE_TO_HORMONE_STIMULUS ( 0.00991330381611599 ); ----------------GOSLIM-------------- GO:0030895 apolipoprotein B mRNA editing enzyme complex ( ); GO:0048038 quinone binding ( ); GO:0008131 amine oxidase activity ( ); GO:0019003 GDP binding ( ); GO:0030331 estrogen receptor binding ( ); GO:0004522 pancreatic ribonuclease activity ( ); GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor ( ); GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters ( ); GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors ( ); GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters ( ); GO:0003727 single-stranded RNA binding ( ); GO:0050821 protein stabilization ( ); GO:0006584 catecholamine metabolic process ( ); GO:0018958 phenol metabolic process ( ); GO:0003725 double-stranded RNA binding ( ); ----------------GO-------------- GO:0030895 apolipoprotein B mRNA editing enzyme complex ( 0.000904613475662286 ); GO:0048038 quinone binding ( 0.000904613475662286 ); GO:0008131 amine oxidase activity ( 0.00150731018915273 ); GO:0019003 GDP binding ( 0.00180854491053573 ); GO:0030331 estrogen receptor binding ( 0.00241078715875942 ); GO:0004522 pancreatic ribonuclease activity ( 0.00421569744366346 ); GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor ( 0.00421569744366346 ); GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters ( 0.00511713158104687 ); GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors ( 0.00541745846827335 ); GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters ( 0.00601788559613137 ); GO:0003727 single-stranded RNA binding ( 0.00631798586717336 ); GO:0050821 protein stabilization ( 0.00721783369117057 ); GO:0006584 catecholamine metabolic process ( 0.00781735490152924 ); GO:0018958 phenol metabolic process ( 0.0081170023505952 ); GO:0003725 double-stranded RNA binding ( 0.00961410864225021 ); ----------------KEGG-------------- hsa00960 Alkaloid biosynthesis II ( 0.00421569744366346 ); hsa00360 Phenylalanine metabolism ( 0.00601788559613137 ); hsa00410 beta-Alanine metabolism ( 0.00721783369117057 ); hsa00260 Glycine, serine and threonine metabolism ( 0.0123041547424798 ); hsa00350 Tyrosine metabolism ( 0.013497774806181 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3216 ========================= ----------------C2-------------- BIOCARTA_EPONFKB_PATHWAY ( 0.00331358277321803 ); BIOCARTA_LONGEVITY_PATHWAY ( 0.00451625108395437 ); ----------------C3-------------- ( ); ----------------C4-------------- module_457 ( 0.00301272658247675 ); module_388 ( 0.00511713158104687 ); GNF2_MSH2 ( 0.00781735490152924 ); module_28 ( 0.00961410864225021 ); ----------------C5-------------- SUPEROXIDE_METABOLIC_PROCESS ( 0.00241078715875942 ); SPLICEOSOME_ASSEMBLY ( 0.00541745846827335 ); OXYGEN_AND_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS ( 0.00541745846827335 ); SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX ( 0.00601788559613137 ); RNA_SPLICING__VIA_TRANSESTERIFICATION_REACTIONS ( 0.00961410864225021 ); ----------------GOSLIM-------------- GO:0001315 age-dependent response to reactive oxygen species ( ); GO:0003068 regulation of systemic arterial blood pressure by acetylcholine ( ); GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure ( ); GO:0003070 regulation of systemic arterial blood pressure by neurotransmitter ( ); GO:0010260 organ senescence ( ); GO:0048773 erythrophore differentiation ( ); GO:0055093 response to hyperoxia ( ); GO:0001306 age-dependent response to oxidative stress ( ); GO:0003032 detection of oxygen ( ); GO:0007571 age-dependent general metabolic decline ( ); GO:0014823 response to activity ( ); GO:0019430 removal of superoxide radicals ( ); GO:0004784 superoxide dismutase activity ( ); GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor ( ); GO:0000303 response to superoxide ( ); GO:0032364 oxygen homeostasis ( ); GO:0045599 negative regulation of fat cell differentiation ( ); GO:0000305 response to oxygen radical ( ); GO:0033483 gas homeostasis ( ); GO:0048147 negative regulation of fibroblast proliferation ( ); GO:0048678 response to axon injury ( ); GO:0010149 senescence ( ); GO:0003085 negative regulation of systemic arterial blood pressure ( ); GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ( ); GO:0045598 regulation of fat cell differentiation ( ); GO:0045776 negative regulation of blood pressure ( ); GO:0010332 response to gamma radiation ( ); GO:0042554 superoxide release ( ); GO:0051881 regulation of mitochondrial membrane potential ( ); GO:0001836 release of cytochrome c from mitochondria ( ); GO:0050931 pigment cell differentiation ( ); GO:0045429 positive regulation of nitric oxide biosynthetic process ( ); GO:0051173 positive regulation of nitrogen compound metabolic process ( ); GO:0043229 intracellular organelle ( ); GO:0043226 organelle ( ); GO:0045428 regulation of nitric oxide biosynthetic process ( ); GO:0006801 superoxide metabolic process ( ); GO:0070013 intracellular organelle lumen ( ); GO:0043233 organelle lumen ( ); GO:0006749 glutathione metabolic process ( ); GO:0031974 membrane-enclosed lumen ( ); GO:0008637 apoptotic mitochondrial changes ( ); GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ( ); GO:0048066 pigmentation during development ( ); GO:0030532 small nuclear ribonucleoprotein complex ( ); GO:0009593 detection of chemical stimulus ( ); GO:0048144 fibroblast proliferation ( ); GO:0048145 regulation of fibroblast proliferation ( ); GO:0051171 regulation of nitrogen compound metabolic process ( ); GO:0055072 iron ion homeostasis ( ); GO:0000387 spliceosomal snRNP biogenesis ( ); GO:0006809 nitric oxide biosynthetic process ( ); GO:0042311 vasodilation ( ); GO:0043524 negative regulation of neuron apoptosis ( ); GO:0046209 nitric oxide metabolic process ( ); GO:0001889 liver development ( ); GO:0010212 response to ionizing radiation ( ); GO:0000245 spliceosome assembly ( ); GO:0042542 response to hydrogen peroxide ( ); GO:0003073 regulation of systemic arterial blood pressure ( ); GO:0009791 post-embryonic development ( ); ----------------GO-------------- GO:0001315 age-dependent response to reactive oxygen species ( 0.000301613632936237 ); GO:0003068 regulation of systemic arterial blood pressure by acetylcholine ( 0.000301613632936237 ); GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure ( 0.000301613632936237 ); GO:0003070 regulation of systemic arterial blood pressure by neurotransmitter ( 0.000301613632936237 ); GO:0010260 organ senescence ( 0.000301613632936237 ); GO:0048773 erythrophore differentiation ( 0.000301613632936237 ); GO:0055093 response to hyperoxia ( 0.000301613632936237 ); GO:0001306 age-dependent response to oxidative stress ( 0.000603151453075101 ); GO:0003032 detection of oxygen ( 0.000603151453075101 ); GO:0007571 age-dependent general metabolic decline ( 0.000603151453075101 ); GO:0014823 response to activity ( 0.000904613475662286 ); GO:0019430 removal of superoxide radicals ( 0.000904613475662286 ); GO:0004784 superoxide dismutase activity ( 0.000904613475662286 ); GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor ( 0.000904613475662286 ); GO:0000303 response to superoxide ( 0.00150731018915273 ); GO:0032364 oxygen homeostasis ( 0.00150731018915273 ); GO:0045599 negative regulation of fat cell differentiation ( 0.00150731018915273 ); GO:0000305 response to oxygen radical ( 0.00180854491053573 ); GO:0033483 gas homeostasis ( 0.00180854491053573 ); GO:0048147 negative regulation of fibroblast proliferation ( 0.00180854491053573 ); GO:0048678 response to axon injury ( 0.00180854491053573 ); GO:0010149 senescence ( 0.00210970389532639 ); GO:0003085 negative regulation of systemic arterial blood pressure ( 0.00241078715875942 ); GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ( 0.0027117947160662 ); GO:0045598 regulation of fat cell differentiation ( 0.00301272658247675 ); GO:0045776 negative regulation of blood pressure ( 0.00331358277321803 ); GO:0010332 response to gamma radiation ( 0.00361436330351461 ); GO:0042554 superoxide release ( 0.00361436330351461 ); GO:0051881 regulation of mitochondrial membrane potential ( 0.00391506818858967 ); GO:0001836 release of cytochrome c from mitochondria ( 0.00421569744366346 ); GO:0050931 pigment cell differentiation ( 0.00421569744366346 ); GO:0045429 positive regulation of nitric oxide biosynthetic process ( 0.00451625108395437 ); GO:0051173 positive regulation of nitrogen compound metabolic process ( 0.00481672912467745 ); GO:0043229 intracellular organelle ( 0.00505646649156603 ); GO:0043226 organelle ( 0.00506752155843727 ); GO:0045428 regulation of nitric oxide biosynthetic process ( 0.00511713158104687 ); GO:0006801 superoxide metabolic process ( 0.00541745846827335 ); GO:0070013 intracellular organelle lumen ( 0.00583489379174147 ); GO:0043233 organelle lumen ( 0.00622297704160533 ); GO:0006749 glutathione metabolic process ( 0.00631798586717336 ); GO:0031974 membrane-enclosed lumen ( 0.00661393583624659 ); GO:0008637 apoptotic mitochondrial changes ( 0.0069179598994944 ); GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ( 0.00721783369117057 ); GO:0048066 pigmentation during development ( 0.00721783369117057 ); GO:0030532 small nuclear ribonucleoprotein complex ( 0.00721783369117057 ); GO:0009593 detection of chemical stimulus ( 0.0075176320201179 ); GO:0048144 fibroblast proliferation ( 0.0075176320201179 ); GO:0048145 regulation of fibroblast proliferation ( 0.0075176320201179 ); GO:0051171 regulation of nitrogen compound metabolic process ( 0.0075176320201179 ); GO:0055072 iron ion homeostasis ( 0.0075176320201179 ); GO:0000387 spliceosomal snRNP biogenesis ( 0.00781735490152924 ); GO:0006809 nitric oxide biosynthetic process ( 0.00781735490152924 ); GO:0042311 vasodilation ( 0.00781735490152924 ); GO:0043524 negative regulation of neuron apoptosis ( 0.00781735490152924 ); GO:0046209 nitric oxide metabolic process ( 0.00781735490152924 ); GO:0001889 liver development ( 0.0081170023505952 ); GO:0010212 response to ionizing radiation ( 0.0081170023505952 ); GO:0000245 spliceosome assembly ( 0.00841657438250376 ); GO:0042542 response to hydrogen peroxide ( 0.00841657438250376 ); GO:0003073 regulation of systemic arterial blood pressure ( 0.0087160710124411 ); GO:0009791 post-embryonic development ( 0.00901549225559073 ); ----------------KEGG-------------- hsa03050 Proteasome ( 0.0131994825443676 ); hsa05322 Systemic lupus erythematosus ( 0.0374112314699058 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0131444047686057 ); ----------------immu-------------- ( 0.0417861857419388 ); ----------------ARE-------------- ( 0.0385606669142564 ); ============================ group3233 ========================= ----------------C2-------------- REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION ( 0.00601788559613137 ); REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION ( 0.0069179598994944 ); KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE ( 0.00781735490152924 ); ----------------C3-------------- ( ); ----------------C4-------------- module_110 ( 0.00451625108395437 ); module_133 ( 0.00451625108395437 ); module_160 ( 0.00451625108395437 ); module_35 ( 0.00481672912467745 ); GNF2_G22P1 ( 0.0087160710124411 ); ----------------C5-------------- CELLULAR_BIOSYNTHETIC_PROCESS ( 0.00348370368543105 ); MACROMOLECULE_BIOSYNTHETIC_PROCESS ( 0.00352792069213628 ); PROTEOGLYCAN_BIOSYNTHETIC_PROCESS ( 0.00391506818858967 ); LIGASE_ACTIVITY__FORMING_CARBON_OXYGEN_BONDS ( 0.00421569744366346 ); SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS ( 0.00481672912467745 ); TRNA_METABOLIC_PROCESS ( 0.00541745846827335 ); PROTEOGLYCAN_METABOLIC_PROCESS ( 0.00571770980156594 ); BIOSYNTHETIC_PROCESS ( 0.00742975829590128 ); SULFOTRANSFERASE_ACTIVITY ( 0.00781735490152924 ); TRANSFERASE_ACTIVITY__TRANSFERRING_SULFUR_CONTAINING_GROUPS ( 0.00901549225559073 ); ----------------GOSLIM-------------- GO:0006430 lysyl-tRNA aminoacylation ( ); GO:0004824 lysine-tRNA ligase activity ( ); GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification ( ); GO:0015012 heparan sulfate proteoglycan biosynthetic process ( ); GO:0005066 transmembrane receptor protein tyrosine kinase signaling protein activity ( ); GO:0048286 alveolus development ( ); GO:0030201 heparan sulfate proteoglycan metabolic process ( ); GO:0030166 proteoglycan biosynthetic process ( ); GO:0005158 insulin receptor binding ( ); GO:0006029 proteoglycan metabolic process ( ); GO:0001890 placenta development ( ); ----------------GO-------------- GO:0006430 lysyl-tRNA aminoacylation ( 0.000301613632936237 ); GO:0004824 lysine-tRNA ligase activity ( 0.000301613632936237 ); GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification ( 0.000904613475662286 ); GO:0015012 heparan sulfate proteoglycan biosynthetic process ( 0.0027117947160662 ); GO:0005066 transmembrane receptor protein tyrosine kinase signaling protein activity ( 0.0027117947160662 ); GO:0048286 alveolus development ( 0.00301272658247675 ); GO:0030201 heparan sulfate proteoglycan metabolic process ( 0.00361436330351461 ); GO:0030166 proteoglycan biosynthetic process ( 0.00601788559613137 ); GO:0005158 insulin receptor binding ( 0.00631798586717336 ); GO:0006029 proteoglycan metabolic process ( 0.0087160710124411 ); GO:0001890 placenta development ( 0.00931483812713418 ); ----------------KEGG-------------- hsa00300 Lysine biosynthesis ( 0.00150731018915273 ); hsa00534 Heparan sulfate biosynthesis ( 0.00571770980156594 ); hsa00970 Aminoacyl-tRNA biosynthesis ( 0.0123041547424798 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0350711246483632 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3247 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$GFI1_01 ( 0.0014257963304545 ); V$LYF1_01 ( 0.00152774940671871 ); MGGAAGTG_V$GABP_B ( 0.00915412895605736 ); ----------------C4-------------- ( ); ----------------C5-------------- MYOBLAST_DIFFERENTIATION ( 0.00511713158104687 ); POSITIVE_REGULATION_OF_PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 0.00601788559613137 ); MUSCLE_CELL_DIFFERENTIATION ( 0.00661801062989487 ); POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION ( 0.0075176320201179 ); POSITIVE_REGULATION_OF_PHOSPHORYLATION ( 0.00781735490152924 ); POSITIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS ( 0.00841657438250376 ); NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION ( 0.00841657438250376 ); BONE_REMODELING ( 0.0087160710124411 ); POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS ( 0.0087160710124411 ); REGULATION_OF_PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 0.00901549225559073 ); TISSUE_REMODELING ( 0.00901549225559073 ); SKELETAL_MUSCLE_DEVELOPMENT ( 0.00931483812713418 ); ----------------GOSLIM-------------- GO:0021978 telencephalon regionalization ( ); GO:0007500 mesodermal cell fate determination ( ); GO:0060235 lens induction in camera-type eye ( ); GO:0032331 negative regulation of chondrocyte differentiation ( ); GO:0033160 positive regulation of protein import into nucleus, translocation ( ); GO:0045662 negative regulation of myoblast differentiation ( ); GO:0060390 regulation of SMAD protein nuclear translocation ( ); GO:0060391 positive regulation of SMAD protein nuclear translocation ( ); GO:0021904 dorsoventral neural tube patterning ( ); GO:0033158 regulation of protein import into nucleus, translocation ( ); GO:0014701 junctional sarcoplasmic reticulum membrane ( ); GO:0002089 lens morphogenesis in camera-type eye ( ); GO:0021871 forebrain regionalization ( ); GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity ( ); GO:0001710 mesodermal cell fate commitment ( ); GO:0032330 regulation of chondrocyte differentiation ( ); GO:0048333 mesodermal cell differentiation ( ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( ); GO:0046030 inositol trisphosphate phosphatase activity ( ); GO:0051049 regulation of transport ( ); GO:0045661 regulation of myoblast differentiation ( ); GO:0021532 neural tube patterning ( ); GO:0051148 negative regulation of muscle cell differentiation ( ); GO:0002088 lens development in camera-type eye ( ); GO:0045843 negative regulation of striated muscle development ( ); GO:0007184 SMAD protein nuclear translocation ( ); GO:0048635 negative regulation of muscle development ( ); GO:0001658 ureteric bud branching ( ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( ); GO:0051145 smooth muscle cell differentiation ( ); GO:0002062 chondrocyte differentiation ( ); GO:0048742 regulation of skeletal muscle fiber development ( ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( ); GO:0030501 positive regulation of bone mineralization ( ); GO:0031128 induction ( ); GO:0045168 cell-cell signaling involved in cell fate commitment ( ); GO:0048641 regulation of skeletal muscle development ( ); GO:0032879 regulation of localization ( ); GO:0070169 positive regulation of biomineral formation ( ); GO:0033017 sarcoplasmic reticulum membrane ( ); GO:0060389 pathway-restricted SMAD protein phosphorylation ( ); GO:0022898 regulation of transmembrane transporter activity ( ); GO:0032409 regulation of transporter activity ( ); GO:0032412 regulation of ion transmembrane transporter activity ( ); GO:0045669 positive regulation of osteoblast differentiation ( ); GO:0045778 positive regulation of ossification ( ); GO:0051147 regulation of muscle cell differentiation ( ); GO:0045445 myoblast differentiation ( ); GO:0060402 calcium ion transport into cytosol ( ); GO:0001657 ureteric bud development ( ); GO:0046852 positive regulation of bone remodeling ( ); GO:0060401 cytosolic calcium ion transport ( ); GO:0030500 regulation of bone mineralization ( ); GO:0032388 positive regulation of intracellular transport ( ); GO:0034105 positive regulation of tissue remodeling ( ); GO:0004437 inositol or phosphatidylinositol phosphatase activity ( ); GO:0070167 regulation of biomineral formation ( ); GO:0042475 odontogenesis of dentine-containing tooth ( ); GO:0001707 mesoderm formation ( ); GO:0045667 regulation of osteoblast differentiation ( ); GO:0001656 metanephros development ( ); GO:0001709 cell fate determination ( ); GO:0048332 mesoderm morphogenesis ( ); GO:0016529 sarcoplasmic reticulum ( ); GO:0001704 formation of primary germ layer ( ); GO:0030282 bone mineralization ( ); GO:0000060 protein import into nucleus, translocation ( ); GO:0021915 neural tube development ( ); GO:0048593 camera-type eye morphogenesis ( ); GO:0048663 neuron fate commitment ( ); GO:0016528 sarcoplasm ( ); GO:0016202 regulation of striated muscle development ( ); GO:0031214 biomineral formation ( ); GO:0048634 regulation of muscle development ( ); ----------------GO-------------- GO:0021978 telencephalon regionalization ( 0.000603151453075101 ); GO:0007500 mesodermal cell fate determination ( 0.000904613475662286 ); GO:0060235 lens induction in camera-type eye ( 0.000904613475662286 ); GO:0032331 negative regulation of chondrocyte differentiation ( 0.00120599971594137 ); GO:0033160 positive regulation of protein import into nucleus, translocation ( 0.00120599971594137 ); GO:0045662 negative regulation of myoblast differentiation ( 0.00120599971594137 ); GO:0060390 regulation of SMAD protein nuclear translocation ( 0.00120599971594137 ); GO:0060391 positive regulation of SMAD protein nuclear translocation ( 0.00120599971594137 ); GO:0021904 dorsoventral neural tube patterning ( 0.00150731018915273 ); GO:0033158 regulation of protein import into nucleus, translocation ( 0.00150731018915273 ); GO:0014701 junctional sarcoplasmic reticulum membrane ( 0.00150731018915273 ); GO:0002089 lens morphogenesis in camera-type eye ( 0.00180854491053573 ); GO:0021871 forebrain regionalization ( 0.00180854491053573 ); GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity ( 0.00180854491053573 ); GO:0001710 mesodermal cell fate commitment ( 0.00210970389532639 ); GO:0032330 regulation of chondrocyte differentiation ( 0.00210970389532639 ); GO:0048333 mesodermal cell differentiation ( 0.00210970389532639 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.00210970389532639 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.00210970389532639 ); GO:0051049 regulation of transport ( 0.00224646984976035 ); GO:0045661 regulation of myoblast differentiation ( 0.00241078715875942 ); GO:0021532 neural tube patterning ( 0.0027117947160662 ); GO:0051148 negative regulation of muscle cell differentiation ( 0.0027117947160662 ); GO:0002088 lens development in camera-type eye ( 0.00301272658247675 ); GO:0045843 negative regulation of striated muscle development ( 0.00301272658247675 ); GO:0007184 SMAD protein nuclear translocation ( 0.00331358277321803 ); GO:0048635 negative regulation of muscle development ( 0.00331358277321803 ); GO:0001658 ureteric bud branching ( 0.00361436330351461 ); GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ( 0.00361436330351461 ); GO:0051145 smooth muscle cell differentiation ( 0.00361436330351461 ); GO:0002062 chondrocyte differentiation ( 0.00391506818858967 ); GO:0048742 regulation of skeletal muscle fiber development ( 0.00391506818858967 ); GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation ( 0.00421569744366346 ); GO:0030501 positive regulation of bone mineralization ( 0.00451625108395437 ); GO:0031128 induction ( 0.00451625108395437 ); GO:0045168 cell-cell signaling involved in cell fate commitment ( 0.00451625108395437 ); GO:0048641 regulation of skeletal muscle development ( 0.00451625108395437 ); GO:0032879 regulation of localization ( 0.00471941236306091 ); GO:0070169 positive regulation of biomineral formation ( 0.00481672912467745 ); GO:0033017 sarcoplasmic reticulum membrane ( 0.00481672912467745 ); GO:0060389 pathway-restricted SMAD protein phosphorylation ( 0.00511713158104687 ); GO:0022898 regulation of transmembrane transporter activity ( 0.00571770980156594 ); GO:0032409 regulation of transporter activity ( 0.00571770980156594 ); GO:0032412 regulation of ion transmembrane transporter activity ( 0.00571770980156594 ); GO:0045669 positive regulation of osteoblast differentiation ( 0.00571770980156594 ); GO:0045778 positive regulation of ossification ( 0.00571770980156594 ); GO:0051147 regulation of muscle cell differentiation ( 0.00571770980156594 ); GO:0045445 myoblast differentiation ( 0.00601788559613137 ); GO:0060402 calcium ion transport into cytosol ( 0.00631798586717336 ); GO:0001657 ureteric bud development ( 0.00661801062989487 ); GO:0046852 positive regulation of bone remodeling ( 0.00661801062989487 ); GO:0060401 cytosolic calcium ion transport ( 0.00661801062989487 ); GO:0030500 regulation of bone mineralization ( 0.0069179598994944 ); GO:0032388 positive regulation of intracellular transport ( 0.0069179598994944 ); GO:0034105 positive regulation of tissue remodeling ( 0.0069179598994944 ); GO:0004437 inositol or phosphatidylinositol phosphatase activity ( 0.0069179598994944 ); GO:0070167 regulation of biomineral formation ( 0.0075176320201179 ); GO:0042475 odontogenesis of dentine-containing tooth ( 0.00781735490152924 ); GO:0001707 mesoderm formation ( 0.0081170023505952 ); GO:0045667 regulation of osteoblast differentiation ( 0.0081170023505952 ); GO:0001656 metanephros development ( 0.0087160710124411 ); GO:0001709 cell fate determination ( 0.0087160710124411 ); GO:0048332 mesoderm morphogenesis ( 0.0087160710124411 ); GO:0016529 sarcoplasmic reticulum ( 0.0087160710124411 ); GO:0001704 formation of primary germ layer ( 0.00901549225559073 ); GO:0030282 bone mineralization ( 0.00901549225559073 ); GO:0000060 protein import into nucleus, translocation ( 0.00931483812713418 ); GO:0021915 neural tube development ( 0.00931483812713418 ); GO:0048593 camera-type eye morphogenesis ( 0.00931483812713418 ); GO:0048663 neuron fate commitment ( 0.00931483812713418 ); GO:0016528 sarcoplasm ( 0.00931483812713418 ); GO:0016202 regulation of striated muscle development ( 0.00961410864225021 ); GO:0031214 biomineral formation ( 0.00991330381611599 ); GO:0048634 regulation of muscle development ( 0.00991330381611599 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.014392200787231 ); hsa05217 Basal cell carcinoma ( 0.0164765669935737 ); hsa04340 Hedgehog signaling pathway ( 0.017071425033122 ); hsa04070 Phosphatidylinositol signaling system ( 0.0227076384538816 ); hsa04350 TGF-beta signaling pathway ( 0.0256632320228238 ); ----------------CARTA-------------- ( 0.00241078715875942 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3255 ========================= ----------------C2-------------- BIOCARTA_STEM_PATHWAY ( 0.00451625108395437 ); BIOCARTA_ETS_PATHWAY ( 0.00541745846827335 ); BIOCARTA_INFLAM_PATHWAY ( 0.00841657438250376 ); REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS ( 0.0087160710124411 ); ----------------C3-------------- ( ); ----------------C4-------------- module_346 ( 0.00511713158104687 ); module_408 ( 0.00541745846827335 ); ----------------C5-------------- ARYLSULFATASE_ACTIVITY ( 0.00361436330351461 ); MYELOID_LEUKOCYTE_DIFFERENTIATION ( 0.00451625108395437 ); SULFURIC_ESTER_HYDROLASE_ACTIVITY ( 0.00481672912467745 ); ATP_DEPENDENT_RNA_HELICASE_ACTIVITY ( 0.00511713158104687 ); RNA_DEPENDENT_ATPASE_ACTIVITY ( 0.00541745846827335 ); RNA_HELICASE_ACTIVITY ( 0.00721783369117057 ); ATP_DEPENDENT_HELICASE_ACTIVITY ( 0.00781735490152924 ); ----------------GOSLIM-------------- GO:0051597 response to methylmercury ( ); GO:0004098 cerebroside-sulfatase activity ( ); GO:0045655 regulation of monocyte differentiation ( ); GO:0045657 positive regulation of monocyte differentiation ( ); GO:0005157 macrophage colony stimulating factor receptor binding ( ); GO:0031232 extrinsic to external side of plasma membrane ( ); GO:0001954 positive regulation of cell-matrix adhesion ( ); GO:0009268 response to pH ( ); GO:0010811 positive regulation of cell-substrate adhesion ( ); GO:0042117 monocyte activation ( ); GO:0030224 monocyte differentiation ( ); GO:0000299 integral to membrane of membrane fraction ( ); GO:0004065 arylsulfatase activity ( ); GO:0010744 positive regulation of foam cell differentiation ( ); GO:0007339 binding of sperm to zona pellucida ( ); GO:0035036 sperm-egg recognition ( ); GO:0004835 tubulin-tyrosine ligase activity ( ); GO:0009988 cell-cell recognition ( ); GO:0045651 positive regulation of macrophage differentiation ( ); GO:0004004 ATP-dependent RNA helicase activity ( ); GO:0008484 sulfuric ester hydrolase activity ( ); GO:0008186 RNA-dependent ATPase activity ( ); GO:0045471 response to ethanol ( ); GO:0001952 regulation of cell-matrix adhesion ( ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( ); GO:0010810 regulation of cell-substrate adhesion ( ); GO:0010743 regulation of foam cell differentiation ( ); GO:0003724 RNA helicase activity ( ); GO:0045785 positive regulation of cell adhesion ( ); GO:0010742 foam cell differentiation ( ); GO:0006914 autophagy ( ); GO:0045649 regulation of macrophage differentiation ( ); GO:0045639 positive regulation of myeloid cell differentiation ( ); GO:0005615 extracellular space ( ); GO:0001669 acrosome ( ); ----------------GO-------------- GO:0051597 response to methylmercury ( 0.000301613632936237 ); GO:0004098 cerebroside-sulfatase activity ( 0.000301613632936237 ); GO:0045655 regulation of monocyte differentiation ( 0.000603151453075101 ); GO:0045657 positive regulation of monocyte differentiation ( 0.000603151453075101 ); GO:0005157 macrophage colony stimulating factor receptor binding ( 0.000603151453075101 ); GO:0031232 extrinsic to external side of plasma membrane ( 0.000904613475662286 ); GO:0001954 positive regulation of cell-matrix adhesion ( 0.00150731018915273 ); GO:0009268 response to pH ( 0.00150731018915273 ); GO:0010811 positive regulation of cell-substrate adhesion ( 0.00150731018915273 ); GO:0042117 monocyte activation ( 0.00150731018915273 ); GO:0030224 monocyte differentiation ( 0.00210970389532639 ); GO:0000299 integral to membrane of membrane fraction ( 0.00331358277321803 ); GO:0004065 arylsulfatase activity ( 0.00361436330351461 ); GO:0010744 positive regulation of foam cell differentiation ( 0.00391506818858967 ); GO:0007339 binding of sperm to zona pellucida ( 0.00421569744366346 ); GO:0035036 sperm-egg recognition ( 0.00421569744366346 ); GO:0004835 tubulin-tyrosine ligase activity ( 0.00421569744366346 ); GO:0009988 cell-cell recognition ( 0.00511713158104687 ); GO:0045651 positive regulation of macrophage differentiation ( 0.00511713158104687 ); GO:0004004 ATP-dependent RNA helicase activity ( 0.00511713158104687 ); GO:0008484 sulfuric ester hydrolase activity ( 0.00511713158104687 ); GO:0008186 RNA-dependent ATPase activity ( 0.00541745846827335 ); GO:0045471 response to ethanol ( 0.00601788559613137 ); GO:0001952 regulation of cell-matrix adhesion ( 0.00631798586717336 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.00631798586717336 ); GO:0010810 regulation of cell-substrate adhesion ( 0.00631798586717336 ); GO:0010743 regulation of foam cell differentiation ( 0.00661801062989487 ); GO:0003724 RNA helicase activity ( 0.0075176320201179 ); GO:0045785 positive regulation of cell adhesion ( 0.00781735490152924 ); GO:0010742 foam cell differentiation ( 0.0081170023505952 ); GO:0006914 autophagy ( 0.00841657438250376 ); GO:0045649 regulation of macrophage differentiation ( 0.00901549225559073 ); GO:0045639 positive regulation of myeloid cell differentiation ( 0.00931483812713418 ); GO:0005615 extracellular space ( 0.0096112244865944 ); GO:0001669 acrosome ( 0.00991330381611599 ); ----------------KEGG-------------- hsa00600 Sphingolipid metabolism ( 0.0117068935426602 ); hsa04640 Hematopoietic cell lineage ( 0.0250727099917203 ); ----------------CARTA-------------- ( 0.00541745846827335 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3288 ========================= ----------------C2-------------- BIOCARTA_GABA_PATHWAY ( 0.00301272658247675 ); KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM ( 0.00661801062989487 ); ----------------C3-------------- ( 0.00124555822910242 ); ----------------C4-------------- module_396 ( 0.00361436330351461 ); module_489 ( 0.00901549225559073 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0000309 nicotinamide-nucleotide adenylyltransferase activity ( ); GO:0008503 benzodiazepine receptor activity ( ); GO:0009435 NAD biosynthetic process ( ); GO:0019363 pyridine nucleotide biosynthetic process ( ); GO:0007214 gamma-aminobutyric acid signaling pathway ( ); GO:0019674 NAD metabolic process ( ); GO:0042364 water-soluble vitamin biosynthetic process ( ); GO:0009110 vitamin biosynthetic process ( ); GO:0004890 GABA-A receptor activity ( ); GO:0016917 GABA receptor activity ( ); GO:0006769 nicotinamide metabolic process ( ); GO:0019362 pyridine nucleotide metabolic process ( ); ----------------GO-------------- GO:0000309 nicotinamide-nucleotide adenylyltransferase activity ( 0.000904613475662286 ); GO:0008503 benzodiazepine receptor activity ( 0.00180854491053573 ); GO:0009435 NAD biosynthetic process ( 0.00241078715875942 ); GO:0019363 pyridine nucleotide biosynthetic process ( 0.00421569744366346 ); GO:0007214 gamma-aminobutyric acid signaling pathway ( 0.00481672912467745 ); GO:0019674 NAD metabolic process ( 0.00481672912467745 ); GO:0042364 water-soluble vitamin biosynthetic process ( 0.00601788559613137 ); GO:0009110 vitamin biosynthetic process ( 0.00661801062989487 ); GO:0004890 GABA-A receptor activity ( 0.0069179598994944 ); GO:0016917 GABA receptor activity ( 0.0081170023505952 ); GO:0006769 nicotinamide metabolic process ( 0.00841657438250376 ); GO:0019362 pyridine nucleotide metabolic process ( 0.00931483812713418 ); ----------------KEGG-------------- ( 0.00721783369117057 ); ----------------CARTA-------------- ifngpathway ( 0.00241078715875942 ); insulinpathway ( 0.00331358277321803 ); at1rpathway ( 0.00361436330351461 ); ifnapathway ( 0.00391506818858967 ); il6pathway ( 0.00421569744366346 ); igf1pathway ( 0.0069179598994944 ); bcrpathway ( 0.0075176320201179 ); tpopathway ( 0.0087160710124411 ); ngfpathway ( 0.00901549225559073 ); metpathway ( 0.0131994825443676 ); pdgfpathway ( 0.013497774806181 ); fcer1pathway ( 0.0146901925632592 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3296 ========================= ----------------C2-------------- REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA ( 0.00601788559613137 ); REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12 ( 0.00631798586717336 ); REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR ( 0.0069179598994944 ); REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1 ( 0.0075176320201179 ); REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA ( 0.0075176320201179 ); REACTOME_G_PROTEIN_ACTIVATION ( 0.0081170023505952 ); REACTOME_GS_ALPHA_MEDIATED_EVENTS_IN_GLUCAGON_SIGNALLING ( 0.0081170023505952 ); REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS ( 0.0081170023505952 ); REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING ( 0.00841657438250376 ); REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE ( 0.0087160710124411 ); REACTOME_SIGNAL_AMPLIFICATION ( 0.00931483812713418 ); REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING ( 0.00961410864225021 ); REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS ( 0.00991330381611599 ); ----------------C3-------------- ( 0.0046939722662892 ); ----------------C4-------------- module_216 ( 0.0027117947160662 ); module_328 ( 0.00421569744366346 ); module_267 ( 0.00451625108395437 ); GNF2_TM4SF2 ( 0.0069179598994944 ); ----------------C5-------------- POSITIVE_REGULATION_OF_ANGIOGENESIS ( 0.0027117947160662 ); NICOTINIC_ACETYLCHOLINE_GATED_RECEPTOR_CHANNEL_COMPLEX ( 0.00331358277321803 ); NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS ( 0.00331358277321803 ); NICOTINIC_ACETYLCHOLINE_ACTIVATED_CATION_SELECTIVE_CHANNEL_ACTIVITY ( 0.00331358277321803 ); REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS ( 0.00451625108395437 ); ACETYLCHOLINE_BINDING ( 0.00511713158104687 ); REGULATION_OF_DEFENSE_RESPONSE ( 0.00601788559613137 ); EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY ( 0.00631798586717336 ); EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY ( 0.00631798586717336 ); CHANNEL_REGULATOR_ACTIVITY ( 0.00661801062989487 ); REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY ( 0.0069179598994944 ); AMINE_BINDING ( 0.0069179598994944 ); ANTIGEN_BINDING ( 0.00721783369117057 ); AUXILIARY_TRANSPORT_PROTEIN_ACTIVITY ( 0.00721783369117057 ); REGULATION_OF_ANGIOGENESIS ( 0.0075176320201179 ); REGULATION_OF_CYTOKINE_PRODUCTION ( 0.0075176320201179 ); CALCIUM_ION_TRANSPORT ( 0.0081170023505952 ); RESPONSE_TO_HYPOXIA ( 0.00841657438250376 ); RESPONSE_TO_ORGANIC_SUBSTANCE ( 0.00901549225559073 ); NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS ( 0.00931483812713418 ); DI___TRI_VALENT_INORGANIC_CATION_TRANSPORT ( 0.00961410864225021 ); ----------------GOSLIM-------------- GO:0065008 regulation of biological quality ( 0.00147952180688376 ); GO:0001988 positive regulation of heart rate in baroreceptor response to decreased systemic arterial blood pressure ( 0.00487874759167023 ); GO:0014061 regulation of norepinephrine secretion ( 0.00147952180688376 ); GO:0060112 generation of ovulation cycle rhythm ( 0.00487874759167023 ); GO:0017081 chloride channel regulator activity ( 0.00147952180688376 ); GO:0001982 baroreceptor response to decreased systemic arterial blood pressure ( 0.00487874759167023 ); GO:0015874 norepinephrine transport ( 0.00147952180688376 ); GO:0048243 norepinephrine secretion ( 0.00487874759167023 ); GO:0032279 asymmetric synapse ( 0.00147952180688376 ); GO:0008179 adenylate cyclase binding ( 0.00487874759167023 ); GO:0010817 regulation of hormone levels ( 0.00147952180688376 ); GO:0032691 negative regulation of interleukin-1 beta production ( 0.00487874759167023 ); GO:0032692 negative regulation of interleukin-1 production ( 0.00147952180688376 ); GO:0048149 behavioral response to ethanol ( 0.00487874759167023 ); GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback ( 0.00147952180688376 ); GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback ( 0.00487874759167023 ); GO:0042416 dopamine biosynthetic process ( 0.00147952180688376 ); GO:0015379 potassium:chloride symporter activity ( 0.00487874759167023 ); GO:0015643 toxin binding ( 0.00147952180688376 ); GO:0032651 regulation of interleukin-1 beta production ( 0.00487874759167023 ); GO:0032715 negative regulation of interleukin-6 production ( 0.00147952180688376 ); GO:0043198 dendritic shaft ( 0.00487874759167023 ); GO:0032611 interleukin-1 beta production ( 0.00147952180688376 ); GO:0032652 regulation of interleukin-1 production ( 0.00487874759167023 ); GO:0040008 regulation of growth ( 0.00147952180688376 ); GO:0010460 positive regulation of heart rate ( 0.00487874759167023 ); GO:0032612 interleukin-1 production ( 0.00147952180688376 ); GO:0032720 negative regulation of tumor necrosis factor production ( 0.00487874759167023 ); GO:0015377 cation:chloride symporter activity ( 0.00147952180688376 ); GO:0003084 positive regulation of systemic arterial blood pressure ( 0.00487874759167023 ); GO:0032225 regulation of synaptic transmission, dopaminergic ( 0.00147952180688376 ); GO:0035095 behavioral response to nicotine ( 0.00487874759167023 ); GO:0006873 cellular ion homeostasis ( 0.00147952180688376 ); GO:0055082 cellular chemical homeostasis ( 0.00487874759167023 ); GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ( 0.00147952180688376 ); GO:0002021 response to dietary excess ( 0.00487874759167023 ); GO:0008306 associative learning ( 0.00147952180688376 ); GO:0032094 response to food ( 0.00487874759167023 ); GO:0042423 catecholamine biosynthetic process ( 0.00147952180688376 ); GO:0045823 positive regulation of heart contraction ( 0.00487874759167023 ); GO:0050433 regulation of catecholamine secretion ( 0.00147952180688376 ); GO:0050801 ion homeostasis ( 0.00487874759167023 ); GO:0035094 response to nicotine ( 0.00147952180688376 ); GO:0050432 catecholamine secretion ( 0.00487874759167023 ); GO:0001540 beta-amyloid binding ( 0.00147952180688376 ); GO:0022603 regulation of anatomical structure morphogenesis ( 0.00487874759167023 ); GO:0001963 synaptic transmission, dopaminergic ( 0.00147952180688376 ); GO:0045777 positive regulation of blood pressure ( 0.00487874759167023 ); GO:0043197 dendritic spine ( 0.00147952180688376 ); GO:0040007 growth ( 0.00487874759167023 ); GO:0007271 synaptic transmission, cholinergic ( 0.00147952180688376 ); GO:0009409 response to cold ( 0.00487874759167023 ); GO:0005892 nicotinic acetylcholine-gated receptor-channel complex ( 0.00147952180688376 ); GO:0014069 postsynaptic density ( 0.00487874759167023 ); GO:0016486 peptide hormone processing ( 0.00147952180688376 ); GO:0050728 negative regulation of inflammatory response ( 0.00487874759167023 ); GO:0019725 cellular homeostasis ( 0.00147952180688376 ); GO:0002027 regulation of heart rate ( 0.00487874759167023 ); GO:0007613 memory ( 0.00147952180688376 ); GO:0031348 negative regulation of defense response ( 0.00487874759167023 ); GO:0042417 dopamine metabolic process ( 0.00147952180688376 ); GO:0042734 presynaptic membrane ( 0.00487874759167023 ); GO:0004889 nicotinic acetylcholine-activated cation-selective channel activity ( 0.00147952180688376 ); GO:0048878 chemical homeostasis ( 0.00487874759167023 ); GO:0051952 regulation of amine transport ( 0.00147952180688376 ); GO:0030317 sperm motility ( 0.00487874759167023 ); GO:0045766 positive regulation of angiogenesis ( 0.00147952180688376 ); GO:0051937 catecholamine transport ( 0.00487874759167023 ); GO:0015464 acetylcholine receptor activity ( 0.00147952180688376 ); GO:0043279 response to alkaloid ( 0.00487874759167023 ); GO:0045471 response to ethanol ( 0.00147952180688376 ); GO:0030426 growth cone ( 0.00487874759167023 ); GO:0042166 acetylcholine binding ( 0.00147952180688376 ); GO:0032680 regulation of tumor necrosis factor production ( 0.00487874759167023 ); GO:0001818 negative regulation of cytokine production ( 0.00147952180688376 ); GO:0032102 negative regulation of response to external stimulus ( 0.00487874759167023 ); GO:0032640 tumor necrosis factor production ( 0.00147952180688376 ); GO:0032675 regulation of interleukin-6 production ( 0.00487874759167023 ); GO:0030427 site of polarized growth ( 0.00147952180688376 ); GO:0042401 biogenic amine biosynthetic process ( 0.00487874759167023 ); GO:0030001 metal ion transport ( 0.00147952180688376 ); GO:0015844 monoamine transport ( 0.00487874759167023 ); GO:0005834 heterotrimeric G-protein complex ( 0.00147952180688376 ); GO:0044425 membrane part ( 0.00487874759167023 ); GO:0006584 catecholamine metabolic process ( 0.00147952180688376 ); GO:0014070 response to organic cyclic substance ( 0.00487874759167023 ); GO:0032635 interleukin-6 production ( 0.00147952180688376 ); GO:0015296 anion:cation symporter activity ( 0.00487874759167023 ); GO:0018958 phenol metabolic process ( 0.00147952180688376 ); GO:0042398 amino acid derivative biosynthetic process ( 0.00487874759167023 ); GO:0005802 trans-Golgi network ( 0.00147952180688376 ); GO:0003073 regulation of systemic arterial blood pressure ( 0.00487874759167023 ); GO:0022602 ovulation cycle process ( 0.00147952180688376 ); GO:0008144 drug binding ( 0.00487874759167023 ); GO:0008324 cation transmembrane transporter activity ( 0.00147952180688376 ); GO:0007270 nerve-nerve synaptic transmission ( 0.00487874759167023 ); GO:0042698 ovulation cycle ( 0.00147952180688376 ); GO:0006812 cation transport ( 0.00487874759167023 ); GO:0007612 learning ( 0.00147952180688376 ); ----------------GO-------------- GO:0065008 regulation of biological quality ( 0.000148125777254208 ); GO:0001988 positive regulation of heart rate in baroreceptor response to decreased systemic arterial blood pressure ( 0.000301613632936237 ); GO:0014061 regulation of norepinephrine secretion ( 0.000301613632936237 ); GO:0060112 generation of ovulation cycle rhythm ( 0.000301613632936237 ); GO:0017081 chloride channel regulator activity ( 0.000301613632936237 ); GO:0001982 baroreceptor response to decreased systemic arterial blood pressure ( 0.000603151453075101 ); GO:0015874 norepinephrine transport ( 0.000603151453075101 ); GO:0048243 norepinephrine secretion ( 0.000603151453075101 ); GO:0032279 asymmetric synapse ( 0.000603151453075101 ); GO:0008179 adenylate cyclase binding ( 0.000603151453075101 ); GO:0010817 regulation of hormone levels ( 0.000797860674824979 ); GO:0032691 negative regulation of interleukin-1 beta production ( 0.000904613475662286 ); GO:0032692 negative regulation of interleukin-1 production ( 0.000904613475662286 ); GO:0048149 behavioral response to ethanol ( 0.000904613475662286 ); GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback ( 0.00120599971594137 ); GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback ( 0.00120599971594137 ); GO:0042416 dopamine biosynthetic process ( 0.00120599971594137 ); GO:0015379 potassium:chloride symporter activity ( 0.00120599971594137 ); GO:0015643 toxin binding ( 0.00120599971594137 ); GO:0032651 regulation of interleukin-1 beta production ( 0.00150731018915273 ); GO:0032715 negative regulation of interleukin-6 production ( 0.00150731018915273 ); GO:0043198 dendritic shaft ( 0.00150731018915273 ); GO:0032611 interleukin-1 beta production ( 0.00180854491053573 ); GO:0032652 regulation of interleukin-1 production ( 0.00180854491053573 ); GO:0040008 regulation of growth ( 0.00205426288122589 ); GO:0010460 positive regulation of heart rate ( 0.00210970389532639 ); GO:0032612 interleukin-1 production ( 0.00210970389532639 ); GO:0032720 negative regulation of tumor necrosis factor production ( 0.00210970389532639 ); GO:0015377 cation:chloride symporter activity ( 0.00210970389532639 ); GO:0003084 positive regulation of systemic arterial blood pressure ( 0.00241078715875942 ); GO:0032225 regulation of synaptic transmission, dopaminergic ( 0.00241078715875942 ); GO:0035095 behavioral response to nicotine ( 0.00241078715875942 ); GO:0006873 cellular ion homeostasis ( 0.0025598036156771 ); GO:0055082 cellular chemical homeostasis ( 0.00265570691624412 ); GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ( 0.0027117947160662 ); GO:0002021 response to dietary excess ( 0.0027117947160662 ); GO:0008306 associative learning ( 0.0027117947160662 ); GO:0032094 response to food ( 0.0027117947160662 ); GO:0042423 catecholamine biosynthetic process ( 0.0027117947160662 ); GO:0045823 positive regulation of heart contraction ( 0.0027117947160662 ); GO:0050433 regulation of catecholamine secretion ( 0.0027117947160662 ); GO:0050801 ion homeostasis ( 0.00307698386910608 ); GO:0035094 response to nicotine ( 0.00331358277321803 ); GO:0050432 catecholamine secretion ( 0.00331358277321803 ); GO:0001540 beta-amyloid binding ( 0.00331358277321803 ); GO:0022603 regulation of anatomical structure morphogenesis ( 0.00341787860723127 ); GO:0001963 synaptic transmission, dopaminergic ( 0.00361436330351461 ); GO:0045777 positive regulation of blood pressure ( 0.00361436330351461 ); GO:0043197 dendritic spine ( 0.00361436330351461 ); GO:0040007 growth ( 0.00373019351444407 ); GO:0007271 synaptic transmission, cholinergic ( 0.00391506818858967 ); GO:0009409 response to cold ( 0.00391506818858967 ); GO:0005892 nicotinic acetylcholine-gated receptor-channel complex ( 0.00391506818858967 ); GO:0014069 postsynaptic density ( 0.00391506818858967 ); GO:0016486 peptide hormone processing ( 0.00421569744366346 ); GO:0050728 negative regulation of inflammatory response ( 0.00421569744366346 ); GO:0019725 cellular homeostasis ( 0.00424723971303218 ); GO:0002027 regulation of heart rate ( 0.00451625108395437 ); GO:0007613 memory ( 0.00451625108395437 ); GO:0031348 negative regulation of defense response ( 0.00451625108395437 ); GO:0042417 dopamine metabolic process ( 0.00451625108395437 ); GO:0042734 presynaptic membrane ( 0.00451625108395437 ); GO:0004889 nicotinic acetylcholine-activated cation-selective channel activity ( 0.00451625108395437 ); GO:0048878 chemical homeostasis ( 0.00459286490615421 ); GO:0051952 regulation of amine transport ( 0.00481672912467745 ); GO:0030317 sperm motility ( 0.00511713158104687 ); GO:0045766 positive regulation of angiogenesis ( 0.00511713158104687 ); GO:0051937 catecholamine transport ( 0.00541745846827335 ); GO:0015464 acetylcholine receptor activity ( 0.00541745846827335 ); GO:0043279 response to alkaloid ( 0.00601788559613137 ); GO:0045471 response to ethanol ( 0.00601788559613137 ); GO:0030426 growth cone ( 0.00601788559613137 ); GO:0042166 acetylcholine binding ( 0.00601788559613137 ); GO:0032680 regulation of tumor necrosis factor production ( 0.00631798586717336 ); GO:0001818 negative regulation of cytokine production ( 0.00661801062989487 ); GO:0032102 negative regulation of response to external stimulus ( 0.00661801062989487 ); GO:0032640 tumor necrosis factor production ( 0.00661801062989487 ); GO:0032675 regulation of interleukin-6 production ( 0.00661801062989487 ); GO:0030427 site of polarized growth ( 0.00661801062989487 ); GO:0042401 biogenic amine biosynthetic process ( 0.0069179598994944 ); GO:0030001 metal ion transport ( 0.00705572879204007 ); GO:0015844 monoamine transport ( 0.00721783369117057 ); GO:0005834 heterotrimeric G-protein complex ( 0.00721783369117057 ); GO:0044425 membrane part ( 0.00764450645218451 ); GO:0006584 catecholamine metabolic process ( 0.00781735490152924 ); GO:0014070 response to organic cyclic substance ( 0.00781735490152924 ); GO:0032635 interleukin-6 production ( 0.00781735490152924 ); GO:0015296 anion:cation symporter activity ( 0.00781735490152924 ); GO:0018958 phenol metabolic process ( 0.0081170023505952 ); GO:0042398 amino acid derivative biosynthetic process ( 0.0081170023505952 ); GO:0005802 trans-Golgi network ( 0.0081170023505952 ); GO:0003073 regulation of systemic arterial blood pressure ( 0.0087160710124411 ); GO:0022602 ovulation cycle process ( 0.00901549225559073 ); GO:0008144 drug binding ( 0.00901549225559073 ); GO:0008324 cation transmembrane transporter activity ( 0.009084722951897 ); GO:0007270 nerve-nerve synaptic transmission ( 0.00931483812713418 ); GO:0042698 ovulation cycle ( 0.00931483812713418 ); GO:0006812 cation transport ( 0.00946948183278429 ); GO:0007612 learning ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3307 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.0012056508074008 ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00331358277321803 ); ----------------GOSLIM-------------- GO:0035110 leg morphogenesis ( ); GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ( ); GO:0034595 phosphoinositide 5-phosphatase activity ( ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( ); GO:0046030 inositol trisphosphate phosphatase activity ( ); GO:0034593 phosphatidylinositol bisphosphate phosphatase activity ( ); GO:0042578 phosphoric ester hydrolase activity ( ); GO:0004437 inositol or phosphatidylinositol phosphatase activity ( ); GO:0004629 phospholipase C activity ( ); ----------------GO-------------- GO:0035110 leg morphogenesis ( 0.000301613632936237 ); GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ( 0.00150731018915273 ); GO:0034595 phosphoinositide 5-phosphatase activity ( 0.00150731018915273 ); GO:0004445 inositol-polyphosphate 5-phosphatase activity ( 0.00210970389532639 ); GO:0046030 inositol trisphosphate phosphatase activity ( 0.00210970389532639 ); GO:0034593 phosphatidylinositol bisphosphate phosphatase activity ( 0.00241078715875942 ); GO:0042578 phosphoric ester hydrolase activity ( 0.00348370368543105 ); GO:0004437 inositol or phosphatidylinositol phosphatase activity ( 0.0069179598994944 ); GO:0004629 phospholipase C activity ( 0.00901549225559073 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.014392200787231 ); hsa04070 Phosphatidylinositol signaling system ( 0.0227076384538816 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3350 ========================= ----------------C2-------------- ( ); ----------------C3-------------- CAGCTTT,MIR-320 ( 0.00174190078130436 ); TTTGCAC,MIR-19A,MIR-19B ( 0.00687210981959569 ); V$PPARA_01 ( 0.0087160710124411 ); TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 ( 0.00925869683200967 ); ----------------C4-------------- module_205 ( 0.00242839579070082 ); GCM_PPM1D ( 0.00631798586717336 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005742 mitochondrial outer membrane translocase complex ( ); GO:0043681 protein import into mitochondrion ( ); GO:0050699 WW domain binding ( ); GO:0008320 protein transmembrane transporter activity ( ); GO:0004298 threonine-type endopeptidase activity ( ); GO:0070003 threonine-type peptidase activity ( ); GO:0006626 protein targeting to mitochondrion ( ); GO:0070011 peptidase activity, acting on L-amino acid peptides ( ); GO:0008233 peptidase activity ( ); ----------------GO-------------- GO:0005742 mitochondrial outer membrane translocase complex ( 0.00180854491053573 ); GO:0043681 protein import into mitochondrion ( 0.00391506818858967 ); GO:0050699 WW domain binding ( 0.00391506818858967 ); GO:0008320 protein transmembrane transporter activity ( 0.00481672912467745 ); GO:0004298 threonine-type endopeptidase activity ( 0.00601788559613137 ); GO:0070003 threonine-type peptidase activity ( 0.00601788559613137 ); GO:0006626 protein targeting to mitochondrion ( 0.0069179598994944 ); GO:0070011 peptidase activity, acting on L-amino acid peptides ( 0.00929367504751739 ); GO:0008233 peptidase activity ( 0.00989762837633593 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.00666131184574116 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0385606669142564 ); ============================ group3410 ========================= ----------------C2-------------- REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE ( 0.00721783369117057 ); REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING ( 0.0087160710124411 ); ----------------C3-------------- V$SEF1_C ( 0.00150731018915273 ); V$PPARG_01 ( 0.00991330381611599 ); ----------------C4-------------- ( 0.00961410864225021 ); ----------------C5-------------- TRANSFERASE_ACTIVITY__TRANSFERRING_PENTOSYL_GROUPS ( 0.00571770980156594 ); INTERMEDIATE_FILAMENT_CYTOSKELETON ( 0.00721783369117057 ); INTERMEDIATE_FILAMENT ( 0.00721783369117057 ); ----------------GOSLIM-------------- GO:0046108 uridine metabolic process ( ); GO:0045098 type III intermediate filament ( ); GO:0004850 uridine phosphorylase activity ( ); GO:0046131 pyrimidine ribonucleoside metabolic process ( ); GO:0008270 zinc ion binding ( ); GO:0006213 pyrimidine nucleoside metabolic process ( ); GO:0046914 transition metal ion binding ( ); GO:0009119 ribonucleoside metabolic process ( ); GO:0005801 cis-Golgi network ( ); GO:0009116 nucleoside metabolic process ( ); GO:0009166 nucleotide catabolic process ( ); ----------------GO-------------- GO:0046108 uridine metabolic process ( 0.000603151453075101 ); GO:0045098 type III intermediate filament ( 0.000603151453075101 ); GO:0004850 uridine phosphorylase activity ( 0.000603151453075101 ); GO:0046131 pyrimidine ribonucleoside metabolic process ( 0.000904613475662286 ); GO:0008270 zinc ion binding ( 0.0017201207149044 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.00241078715875942 ); GO:0046914 transition metal ion binding ( 0.00346512413593054 ); GO:0009119 ribonucleoside metabolic process ( 0.00391506818858967 ); GO:0005801 cis-Golgi network ( 0.00421569744366346 ); GO:0009116 nucleoside metabolic process ( 0.00931483812713418 ); GO:0009166 nucleotide catabolic process ( 0.00991330381611599 ); ----------------KEGG-------------- hsa00983 Drug metabolism - other enzymes ( 0.0131994825443676 ); hsa00240 Pyrimidine metabolism ( 0.0271382331746226 ); hsa04360 Axon guidance ( 0.0382875513565588 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3473 ========================= ----------------C2-------------- REACTOME_SMOOTH_MUSCLE_CONTRACTION ( 0.0069179598994944 ); REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS ( 0.00841657438250376 ); REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN ( 0.00841657438250376 ); REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY ( 0.00841657438250376 ); REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN ( 0.0087160710124411 ); REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA ( 0.00901549225559073 ); REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS ( 0.00901549225559073 ); REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA ( 0.00931483812713418 ); ----------------C3-------------- ATGCACG,MIR-517B ( 0.00391506818858967 ); V$PAX3_01 ( 0.00451625108395437 ); ----------------C4-------------- ( ); ----------------C5-------------- POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.00301272658247675 ); FOCAL_ADHESION ( 0.00331358277321803 ); ACTIN_FILAMENT_BUNDLE_FORMATION ( 0.00361436330351461 ); CELL_SUBSTRATE_ADHERENS_JUNCTION ( 0.00421569744366346 ); CELL_MATRIX_JUNCTION ( 0.00481672912467745 ); ADHERENS_JUNCTION ( 0.00631798586717336 ); TRANS_GOLGI_NETWORK ( 0.00631798586717336 ); ACTIN_FILAMENT_ORGANIZATION ( 0.0069179598994944 ); REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.0087160710124411 ); BASOLATERAL_PLASMA_MEMBRANE ( 0.00991330381611599 ); SMALL_GTPASE_BINDING ( 0.00991330381611599 ); ----------------GOSLIM-------------- GO:0030306 ADP-ribosylation factor binding ( ); GO:0032233 positive regulation of actin filament bundle formation ( ); GO:0051496 positive regulation of stress fiber formation ( ); GO:0033081 regulation of T cell differentiation in the thymus ( ); GO:0017166 vinculin binding ( ); GO:0032231 regulation of actin filament bundle formation ( ); GO:0051492 regulation of stress fiber formation ( ); GO:0043149 stress fiber formation ( ); GO:0006886 intracellular protein transport ( ); GO:0034613 cellular protein localization ( ); GO:0051495 positive regulation of cytoskeleton organization ( ); GO:0051017 actin filament bundle formation ( ); GO:0033077 T cell differentiation in the thymus ( ); GO:0030131 clathrin adaptor complex ( ); GO:0030119 AP-type membrane coat adaptor complex ( ); GO:0005802 trans-Golgi network ( ); GO:0043410 positive regulation of MAPKKK cascade ( ); GO:0010638 positive regulation of organelle organization ( ); GO:0045580 regulation of T cell differentiation ( ); GO:0030118 clathrin coat ( ); ----------------GO-------------- GO:0030306 ADP-ribosylation factor binding ( 0.000603151453075101 ); GO:0032233 positive regulation of actin filament bundle formation ( 0.000904613475662286 ); GO:0051496 positive regulation of stress fiber formation ( 0.000904613475662286 ); GO:0033081 regulation of T cell differentiation in the thymus ( 0.00180854491053573 ); GO:0017166 vinculin binding ( 0.00210970389532639 ); GO:0032231 regulation of actin filament bundle formation ( 0.00241078715875942 ); GO:0051492 regulation of stress fiber formation ( 0.00241078715875942 ); GO:0043149 stress fiber formation ( 0.0027117947160662 ); GO:0006886 intracellular protein transport ( 0.00537654705202212 ); GO:0034613 cellular protein localization ( 0.00587468901766473 ); GO:0051495 positive regulation of cytoskeleton organization ( 0.00601788559613137 ); GO:0051017 actin filament bundle formation ( 0.00631798586717336 ); GO:0033077 T cell differentiation in the thymus ( 0.00661801062989487 ); GO:0030131 clathrin adaptor complex ( 0.0075176320201179 ); GO:0030119 AP-type membrane coat adaptor complex ( 0.00781735490152924 ); GO:0005802 trans-Golgi network ( 0.0081170023505952 ); GO:0043410 positive regulation of MAPKKK cascade ( 0.00841657438250376 ); GO:0010638 positive regulation of organelle organization ( 0.00901549225559073 ); GO:0045580 regulation of T cell differentiation ( 0.00901549225559073 ); GO:0030118 clathrin coat ( 0.00991330381611599 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3531 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- B_CELL_DIFFERENTIATION ( 0.00331358277321803 ); SPECIFIC_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY ( 0.00331358277321803 ); INOSITOL_OR_PHOSPHATIDYLINOSITOL_KINASE_ACTIVITY ( 0.00511713158104687 ); HISTONE_DEACETYLASE_COMPLEX ( 0.00541745846827335 ); B_CELL_ACTIVATION ( 0.00541745846827335 ); LYMPHOCYTE_DIFFERENTIATION ( 0.0075176320201179 ); ----------------GOSLIM-------------- GO:0008440 inositol trisphosphate 3-kinase activity ( ); GO:0051766 inositol trisphosphate kinase activity ( ); GO:0045843 negative regulation of striated muscle development ( ); GO:0048635 negative regulation of muscle development ( ); GO:0016575 histone deacetylation ( ); GO:0006476 protein amino acid deacetylation ( ); GO:0004407 histone deacetylase activity ( ); GO:0016566 specific transcriptional repressor activity ( ); GO:0033558 protein deacetylase activity ( ); GO:0019213 deacetylase activity ( ); GO:0000118 histone deacetylase complex ( ); GO:0016202 regulation of striated muscle development ( ); GO:0048634 regulation of muscle development ( ); ----------------GO-------------- GO:0008440 inositol trisphosphate 3-kinase activity ( 0.00210970389532639 ); GO:0051766 inositol trisphosphate kinase activity ( 0.00241078715875942 ); GO:0045843 negative regulation of striated muscle development ( 0.00301272658247675 ); GO:0048635 negative regulation of muscle development ( 0.00331358277321803 ); GO:0016575 histone deacetylation ( 0.00391506818858967 ); GO:0006476 protein amino acid deacetylation ( 0.00541745846827335 ); GO:0004407 histone deacetylase activity ( 0.00571770980156594 ); GO:0016566 specific transcriptional repressor activity ( 0.00571770980156594 ); GO:0033558 protein deacetylase activity ( 0.00571770980156594 ); GO:0019213 deacetylase activity ( 0.00661801062989487 ); GO:0000118 histone deacetylase complex ( 0.00781735490152924 ); GO:0016202 regulation of striated muscle development ( 0.00961410864225021 ); GO:0048634 regulation of muscle development ( 0.00991330381611599 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.014392200787231 ); hsa04070 Phosphatidylinositol signaling system ( 0.0227076384538816 ); ----------------CARTA-------------- erkpathway ( 0.00150731018915273 ); npp1pathway ( 0.00210970389532639 ); cardiacegfpathway ( 0.00241078715875942 ); melanocytepathway ( 0.00391506818858967 ); tffpathway ( 0.00451625108395437 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0385606669142564 ); ============================ group3576 ========================= ----------------C2-------------- REACTOME_P2Y_RECEPTORS ( 0.00361436330351461 ); REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS ( 0.00451625108395437 ); REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS ( 0.00481672912467745 ); ----------------C3-------------- V$RFX1_02 ( 0.00128609877243903 ); TGATTTRY_V$GFI1_01 ( 0.00196964601410394 ); TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 ( 0.00925869683200967 ); ----------------C4-------------- ( 0.00841657438250376 ); ----------------C5-------------- CORTICAL_ACTIN_CYTOSKELETON ( 0.00391506818858967 ); CORTICAL_CYTOSKELETON ( 0.00601788559613137 ); CELL_CORTEX_PART ( 0.00721783369117057 ); ----------------GOSLIM-------------- GO:0001608 nucleotide receptor activity, G-protein coupled ( ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( ); GO:0001614 purinergic nucleotide receptor activity ( ); GO:0016502 nucleotide receptor activity ( ); GO:0030036 actin cytoskeleton organization ( ); GO:0030029 actin filament-based process ( ); GO:0030742 GTP-dependent protein binding ( ); GO:0008091 spectrin ( ); GO:0048536 spleen development ( ); GO:0007010 cytoskeleton organization ( ); GO:0030178 negative regulation of Wnt receptor signaling pathway ( ); GO:0030864 cortical actin cytoskeleton ( ); GO:0051016 barbed-end actin filament capping ( ); GO:0051693 actin filament capping ( ); GO:0001637 G-protein chemoattractant receptor activity ( ); GO:0004950 chemokine receptor activity ( ); GO:0030835 negative regulation of actin filament depolymerization ( ); GO:0019956 chemokine binding ( ); GO:0030042 actin filament depolymerization ( ); GO:0030834 regulation of actin filament depolymerization ( ); GO:0030837 negative regulation of actin filament polymerization ( ); GO:0030111 regulation of Wnt receptor signaling pathway ( ); GO:0032272 negative regulation of protein polymerization ( ); GO:0030863 cortical cytoskeleton ( ); GO:0031333 negative regulation of protein complex assembly ( ); ----------------GO-------------- GO:0001608 nucleotide receptor activity, G-protein coupled ( 2.65212258176928e-05 ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( 2.65212258176928e-05 ); GO:0001614 purinergic nucleotide receptor activity ( 4.23488390560726e-05 ); GO:0016502 nucleotide receptor activity ( 4.23488390560726e-05 ); GO:0030036 actin cytoskeleton organization ( 0.00164845242201023 ); GO:0030029 actin filament-based process ( 0.00191970307091327 ); GO:0030742 GTP-dependent protein binding ( 0.00241078715875942 ); GO:0008091 spectrin ( 0.0027117947160662 ); GO:0048536 spleen development ( 0.00481672912467745 ); GO:0007010 cytoskeleton organization ( 0.00492527965680823 ); GO:0030178 negative regulation of Wnt receptor signaling pathway ( 0.00511713158104687 ); GO:0030864 cortical actin cytoskeleton ( 0.00601788559613137 ); GO:0051016 barbed-end actin filament capping ( 0.0069179598994944 ); GO:0051693 actin filament capping ( 0.0069179598994944 ); GO:0001637 G-protein chemoattractant receptor activity ( 0.0069179598994944 ); GO:0004950 chemokine receptor activity ( 0.0069179598994944 ); GO:0030835 negative regulation of actin filament depolymerization ( 0.0075176320201179 ); GO:0019956 chemokine binding ( 0.0075176320201179 ); GO:0030042 actin filament depolymerization ( 0.0081170023505952 ); GO:0030834 regulation of actin filament depolymerization ( 0.0081170023505952 ); GO:0030837 negative regulation of actin filament polymerization ( 0.0087160710124411 ); GO:0030111 regulation of Wnt receptor signaling pathway ( 0.00901549225559073 ); GO:0032272 negative regulation of protein polymerization ( 0.00901549225559073 ); GO:0030863 cortical cytoskeleton ( 0.00901549225559073 ); GO:0031333 negative regulation of protein complex assembly ( 0.00961410864225021 ); ----------------KEGG-------------- ( 0.0391632063235058 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3587 ========================= ----------------C2-------------- BIOCARTA_TID_PATHWAY ( 0.00571770980156594 ); BIOCARTA_GLEEVEC_PATHWAY ( 0.0069179598994944 ); ----------------C3-------------- V$YY1_Q6 ( 0.000991505878547754 ); GCCATNTTG_V$YY1_Q6 ( 0.00311865652608249 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0019086 late viral mRNA transcription ( ); GO:0007266 Rho protein signal transduction ( ); GO:0000429 regulation of transcription from RNA polymerase II promoter by carbon catabolites ( ); GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose ( ); GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose ( ); GO:0000436 positive regulation of transcription from RNA polymerase II promoter by carbon catabolites ( ); GO:0045991 positive regulation of transcription by carbon catabolites ( ); GO:0046016 positive regulation of transcription by glucose ( ); GO:0045990 regulation of transcription by carbon catabolites ( ); GO:0046015 regulation of transcription by glucose ( ); GO:0019080 viral genome expression ( ); GO:0019083 viral transcription ( ); GO:0031670 cellular response to nutrient ( ); GO:0051918 negative regulation of fibrinolysis ( ); GO:0043425 bHLH transcription factor binding ( ); GO:0009299 mRNA transcription ( ); GO:0051917 regulation of fibrinolysis ( ); GO:0007265 Ras protein signal transduction ( ); GO:0042730 fibrinolysis ( ); GO:0010552 positive regulation of specific transcription from RNA polymerase II promoter ( ); GO:0030195 negative regulation of blood coagulation ( ); GO:0050819 negative regulation of coagulation ( ); GO:0007264 small GTPase mediated signal transduction ( ); GO:0031669 cellular response to nutrient levels ( ); GO:0003705 RNA polymerase II transcription factor activity, enhancer binding ( ); GO:0030193 regulation of blood coagulation ( ); GO:0050818 regulation of coagulation ( ); GO:0033500 carbohydrate homeostasis ( ); GO:0042593 glucose homeostasis ( ); ----------------GO-------------- GO:0019086 late viral mRNA transcription ( 0.000301613632936237 ); GO:0007266 Rho protein signal transduction ( 0.000497992280898689 ); GO:0000429 regulation of transcription from RNA polymerase II promoter by carbon catabolites ( 0.000603151453075101 ); GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose ( 0.000603151453075101 ); GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose ( 0.000603151453075101 ); GO:0000436 positive regulation of transcription from RNA polymerase II promoter by carbon catabolites ( 0.000603151453075101 ); GO:0045991 positive regulation of transcription by carbon catabolites ( 0.000603151453075101 ); GO:0046016 positive regulation of transcription by glucose ( 0.000603151453075101 ); GO:0045990 regulation of transcription by carbon catabolites ( 0.000904613475662286 ); GO:0046015 regulation of transcription by glucose ( 0.000904613475662286 ); GO:0019080 viral genome expression ( 0.00120599971594137 ); GO:0019083 viral transcription ( 0.00120599971594137 ); GO:0031670 cellular response to nutrient ( 0.00150731018915273 ); GO:0051918 negative regulation of fibrinolysis ( 0.00150731018915273 ); GO:0043425 bHLH transcription factor binding ( 0.00150731018915273 ); GO:0009299 mRNA transcription ( 0.00241078715875942 ); GO:0051917 regulation of fibrinolysis ( 0.00241078715875942 ); GO:0007265 Ras protein signal transduction ( 0.00269454343167052 ); GO:0042730 fibrinolysis ( 0.00511713158104687 ); GO:0010552 positive regulation of specific transcription from RNA polymerase II promoter ( 0.00661801062989487 ); GO:0030195 negative regulation of blood coagulation ( 0.00721783369117057 ); GO:0050819 negative regulation of coagulation ( 0.00781735490152924 ); GO:0007264 small GTPase mediated signal transduction ( 0.00784512957680962 ); GO:0031669 cellular response to nutrient levels ( 0.00841657438250376 ); GO:0003705 RNA polymerase II transcription factor activity, enhancer binding ( 0.00841657438250376 ); GO:0030193 regulation of blood coagulation ( 0.0087160710124411 ); GO:0050818 regulation of coagulation ( 0.00931483812713418 ); GO:0033500 carbohydrate homeostasis ( 0.00961410864225021 ); GO:0042593 glucose homeostasis ( 0.00961410864225021 ); ----------------KEGG-------------- ( 0.0221156241134317 ); ----------------CARTA-------------- proteasomepathway ( 0.0027117947160662 ); gata3pathway ( 0.00451625108395437 ); hbxpathway ( 0.0081170023505952 ); hcmvpathway ( 0.00901549225559073 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3601 ========================= ----------------C2-------------- ( 0.00781735490152924 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity ( ); GO:0048531 beta-1,3-galactosyltransferase activity ( ); GO:0009312 oligosaccharide biosynthetic process ( ); GO:0035250 UDP-galactosyltransferase activity ( ); GO:0009311 oligosaccharide metabolic process ( ); GO:0008378 galactosyltransferase activity ( ); ----------------GO-------------- GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity ( 0.00210970389532639 ); GO:0048531 beta-1,3-galactosyltransferase activity ( 0.00241078715875942 ); GO:0009312 oligosaccharide biosynthetic process ( 0.0027117947160662 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00481672912467745 ); GO:0009311 oligosaccharide metabolic process ( 0.00541745846827335 ); GO:0008378 galactosyltransferase activity ( 0.0087160710124411 ); ----------------KEGG-------------- hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series ( 0.00781735490152924 ); hsa01031 Glycan structures - biosynthesis 2 ( 0.0188542005336108 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3603 ========================= ----------------C2-------------- KEGG_PROTEIN_EXPORT ( 0.0069179598994944 ); REACTOME_PHOSPHOLIPASE_CMEDIATED_CASCADE ( 0.0069179598994944 ); REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION ( 0.0081170023505952 ); REACTOME_FRS2MEDIATED_CASCADE ( 0.0081170023505952 ); ----------------C3-------------- ( 0.00241078715875942 ); ----------------C4-------------- module_99 ( 0.00417485195251989 ); CAR_MYST2 ( 0.0081170023505952 ); CAR_TNFRSF25 ( 0.00901549225559073 ); ----------------C5-------------- HORMONE_BINDING ( 0.00391506818858967 ); AEROBIC_RESPIRATION ( 0.00451625108395437 ); CELLULAR_RESPIRATION ( 0.00571770980156594 ); NEUROPEPTIDE_RECEPTOR_ACTIVITY ( 0.00661801062989487 ); MITOCHONDRIAL_RESPIRATORY_CHAIN ( 0.0069179598994944 ); NEUROPEPTIDE_BINDING ( 0.0069179598994944 ); ----------------GOSLIM-------------- GO:0004978 adrenocorticotropin receptor activity ( ); GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly ( ); GO:0032780 negative regulation of ATPase activity ( ); GO:0043461 proton-transporting ATP synthase complex assembly ( ); GO:0070272 proton-transporting ATP synthase complex biogenesis ( ); GO:0070071 proton-transporting two-sector ATPase complex assembly ( ); GO:0004977 melanocortin receptor activity ( ); GO:0005007 fibroblast growth factor receptor activity ( ); GO:0051354 negative regulation of oxidoreductase activity ( ); GO:0010257 NADH dehydrogenase complex assembly ( ); GO:0032981 mitochondrial respiratory chain complex I assembly ( ); GO:0033108 mitochondrial respiratory chain complex assembly ( ); GO:0051205 protein insertion into membrane ( ); GO:0032592 integral to mitochondrial membrane ( ); GO:0015035 protein disulfide oxidoreductase activity ( ); GO:0043462 regulation of ATPase activity ( ); GO:0051668 localization within membrane ( ); GO:0015036 disulfide oxidoreductase activity ( ); GO:0051341 regulation of oxidoreductase activity ( ); GO:0042562 hormone binding ( ); GO:0008543 fibroblast growth factor receptor signaling pathway ( ); GO:0051346 negative regulation of hydrolase activity ( ); ----------------GO-------------- GO:0004978 adrenocorticotropin receptor activity ( 0.000301613632936237 ); GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly ( 0.000603151453075101 ); GO:0032780 negative regulation of ATPase activity ( 0.000904613475662286 ); GO:0043461 proton-transporting ATP synthase complex assembly ( 0.000904613475662286 ); GO:0070272 proton-transporting ATP synthase complex biogenesis ( 0.000904613475662286 ); GO:0070071 proton-transporting two-sector ATPase complex assembly ( 0.00120599971594137 ); GO:0004977 melanocortin receptor activity ( 0.00150731018915273 ); GO:0005007 fibroblast growth factor receptor activity ( 0.00150731018915273 ); GO:0051354 negative regulation of oxidoreductase activity ( 0.00180854491053573 ); GO:0010257 NADH dehydrogenase complex assembly ( 0.00210970389532639 ); GO:0032981 mitochondrial respiratory chain complex I assembly ( 0.00210970389532639 ); GO:0033108 mitochondrial respiratory chain complex assembly ( 0.00210970389532639 ); GO:0051205 protein insertion into membrane ( 0.00241078715875942 ); GO:0032592 integral to mitochondrial membrane ( 0.00301272658247675 ); GO:0015035 protein disulfide oxidoreductase activity ( 0.00391506818858967 ); GO:0043462 regulation of ATPase activity ( 0.00421569744366346 ); GO:0051668 localization within membrane ( 0.00421569744366346 ); GO:0015036 disulfide oxidoreductase activity ( 0.00511713158104687 ); GO:0051341 regulation of oxidoreductase activity ( 0.00721783369117057 ); GO:0042562 hormone binding ( 0.00841657438250376 ); GO:0008543 fibroblast growth factor receptor signaling pathway ( 0.00931483812713418 ); GO:0051346 negative regulation of hydrolase activity ( 0.00931483812713418 ); ----------------KEGG-------------- hsa03060 Protein export ( 0.00301272658247675 ); hsa05215 Prostate cancer ( 0.0262534559535107 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0033095065232927 ); ----------------ARE-------------- ( ); ============================ group3629 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- MALE_GONAD_DEVELOPMENT ( 0.00361436330351461 ); DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY ( 0.00421569744366346 ); DNA_POLYMERASE_ACTIVITY ( 0.00541745846827335 ); DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS ( 0.00781735490152924 ); ----------------GOSLIM-------------- GO:0000262 mitochondrial chromosome ( 0.000603151453075101 ); GO:0009295 nucleoid ( 0.000603151453075101 ); GO:0042645 mitochondrial nucleoid ( 0.000603151453075101 ); GO:0006426 glycyl-tRNA aminoacylation ( 0.000603151453075101 ); GO:0000229 cytoplasmic chromosome ( 0.000603151453075101 ); GO:0004820 glycine-tRNA ligase activity ( 0.000603151453075101 ); GO:0008584 male gonad development ( 0.000603151453075101 ); ----------------GO-------------- GO:0000262 mitochondrial chromosome ( 0.000301613632936237 ); GO:0009295 nucleoid ( 0.000301613632936237 ); GO:0042645 mitochondrial nucleoid ( 0.000301613632936237 ); GO:0006426 glycyl-tRNA aminoacylation ( 0.000603151453075101 ); GO:0000229 cytoplasmic chromosome ( 0.000603151453075101 ); GO:0004820 glycine-tRNA ligase activity ( 0.000603151453075101 ); GO:0008584 male gonad development ( 0.00841657438250376 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3654 ========================= ----------------C2-------------- REACTOME_TOLL_RECEPTOR_CASCADES ( 0.000255202028491208 ); KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY ( 0.000363011252926204 ); REACTOME_INNATE_IMMUNITY_SIGNALING ( 0.000400532390618158 ); REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES ( 0.00301272658247675 ); REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS ( 0.00331358277321803 ); REACTOME_SIGNALING_IN_IMMUNE_SYSTEM ( 0.00391450760737765 ); REACTOME_P75NTR_SIGNALS_VIA_NFKB ( 0.00391506818858967 ); REACTOME_MYD88_CASCADE ( 0.00571770980156594 ); BIOCARTA_NFKB_PATHWAY ( 0.00661801062989487 ); REACTOME_TOLL_LIKE_RECEPTOR_9_CASCADE ( 0.0069179598994944 ); BIOCARTA_NTHI_PATHWAY ( 0.00721783369117057 ); REACTOME_ACTIVATED_TLR4_SIGNALLING ( 0.00721783369117057 ); BIOCARTA_GSK3_PATHWAY ( 0.0081170023505952 ); REACTOME_TOLL_LIKE_RECEPTOR_4_CASCADE ( 0.00841657438250376 ); REACTOME_PURINE_METABOLISM ( 0.0087160710124411 ); BIOCARTA_IL1R_PATHWAY ( 0.00961410864225021 ); ----------------C3-------------- ( 0.00124555822910242 ); ----------------C4-------------- module_496 ( 0.00180854491053573 ); module_46 ( 0.00518846409990572 ); module_75 ( 0.00532248591200123 ); module_73 ( 0.00631798586717336 ); GNF2_LYN ( 0.0075176320201179 ); GNF2_PAK2 ( 0.0081170023505952 ); module_265 ( 0.0081170023505952 ); ----------------C5-------------- POSITIVE_REGULATION_OF_DEFENSE_RESPONSE ( 0.00301272658247675 ); REGULATION_OF_CELL_CELL_ADHESION ( 0.00301272658247675 ); LEUKOCYTE_CHEMOTAXIS ( 0.00331358277321803 ); POSITIVE_REGULATION_OF_CELL_ADHESION ( 0.00391506818858967 ); LEUKOCYTE_MIGRATION ( 0.00391506818858967 ); REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS ( 0.00451625108395437 ); RECEPTOR_BINDING ( 0.00482182493508466 ); REGULATION_OF_DEFENSE_RESPONSE ( 0.00601788559613137 ); CALCIUM_INDEPENDENT_CELL_CELL_ADHESION ( 0.00661801062989487 ); CYTOKINE_AND_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY ( 0.00661801062989487 ); ----------------GOSLIM-------------- GO:0031349 positive regulation of defense response ( 0.004857532445722 ); GO:0019221 cytokine-mediated signaling pathway ( 0.00657112954497519 ); GO:0031347 regulation of defense response ( 0.004857532445722 ); GO:0016338 calcium-independent cell-cell adhesion ( 0.00657112954497519 ); GO:0050902 leukocyte adhesive activation ( 0.004857532445722 ); GO:0051040 regulation of calcium-independent cell-cell adhesion ( 0.00657112954497519 ); GO:0051041 positive regulation of calcium-independent cell-cell adhesion ( 0.004857532445722 ); GO:0006357 regulation of transcription from RNA polymerase II promoter ( 0.00657112954497519 ); GO:0009615 response to virus ( 0.004857532445722 ); GO:0002238 response to molecule of fungal origin ( 0.00657112954497519 ); GO:0008063 Toll signaling pathway ( 0.004857532445722 ); GO:0003938 IMP dehydrogenase activity ( 0.00657112954497519 ); GO:0048584 positive regulation of response to stimulus ( 0.004857532445722 ); GO:0006366 transcription from RNA polymerase II promoter ( 0.00657112954497519 ); GO:0002755 MyD88-dependent toll-like receptor signaling pathway ( 0.004857532445722 ); GO:0006177 GMP biosynthetic process ( 0.00657112954497519 ); GO:0046037 GMP metabolic process ( 0.004857532445722 ); GO:0005121 Toll binding ( 0.00657112954497519 ); GO:0051707 response to other organism ( 0.004857532445722 ); GO:0002221 pattern recognition receptor signaling pathway ( 0.00657112954497519 ); GO:0002224 toll-like receptor signaling pathway ( 0.004857532445722 ); GO:0048583 regulation of response to stimulus ( 0.00657112954497519 ); GO:0002218 activation of innate immune response ( 0.004857532445722 ); GO:0002758 innate immune response-activating signal transduction ( 0.00657112954497519 ); GO:0022409 positive regulation of cell-cell adhesion ( 0.004857532445722 ); GO:0032760 positive regulation of tumor necrosis factor production ( 0.00657112954497519 ); GO:0045080 positive regulation of chemokine biosynthetic process ( 0.004857532445722 ); GO:0003785 actin monomer binding ( 0.00657112954497519 ); GO:0005123 death receptor binding ( 0.004857532445722 ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( 0.00657112954497519 ); GO:0045073 regulation of chemokine biosynthetic process ( 0.004857532445722 ); GO:0045123 cellular extravasation ( 0.00657112954497519 ); GO:0045351 type I interferon biosynthetic process ( 0.004857532445722 ); GO:0032606 type I interferon production ( 0.00657112954497519 ); GO:0042033 chemokine biosynthetic process ( 0.004857532445722 ); GO:0050755 chemokine metabolic process ( 0.00657112954497519 ); GO:0046330 positive regulation of JNK cascade ( 0.004857532445722 ); GO:0009607 response to biotic stimulus ( 0.00657112954497519 ); GO:0006954 inflammatory response ( 0.004857532445722 ); GO:0032642 regulation of chemokine production ( 0.00657112954497519 ); GO:0032602 chemokine production ( 0.004857532445722 ); GO:0050896 response to stimulus ( 0.00657112954497519 ); GO:0022407 regulation of cell-cell adhesion ( 0.004857532445722 ); GO:0046328 regulation of JNK cascade ( 0.00657112954497519 ); GO:0009126 purine nucleoside monophosphate metabolic process ( 0.004857532445722 ); GO:0009127 purine nucleoside monophosphate biosynthetic process ( 0.00657112954497519 ); GO:0009167 purine ribonucleoside monophosphate metabolic process ( 0.004857532445722 ); GO:0009168 purine ribonucleoside monophosphate biosynthetic process ( 0.00657112954497519 ); GO:0048661 positive regulation of smooth muscle cell proliferation ( 0.004857532445722 ); GO:0009620 response to fungus ( 0.00657112954497519 ); GO:0032496 response to lipopolysaccharide ( 0.004857532445722 ); GO:0050729 positive regulation of inflammatory response ( 0.00657112954497519 ); GO:0032680 regulation of tumor necrosis factor production ( 0.004857532445722 ); GO:0009156 ribonucleoside monophosphate biosynthetic process ( 0.00657112954497519 ); GO:0009161 ribonucleoside monophosphate metabolic process ( 0.004857532445722 ); GO:0032640 tumor necrosis factor production ( 0.00657112954497519 ); GO:0045089 positive regulation of innate immune response ( 0.004857532445722 ); GO:0009123 nucleoside monophosphate metabolic process ( 0.00657112954497519 ); GO:0009124 nucleoside monophosphate biosynthetic process ( 0.004857532445722 ); GO:0009611 response to wounding ( 0.00657112954497519 ); GO:0002237 response to molecule of bacterial origin ( 0.004857532445722 ); GO:0048660 regulation of smooth muscle cell proliferation ( 0.00657112954497519 ); GO:0048659 smooth muscle cell proliferation ( 0.004857532445722 ); GO:0045088 regulation of innate immune response ( 0.00657112954497519 ); GO:0045785 positive regulation of cell adhesion ( 0.004857532445722 ); GO:0043410 positive regulation of MAPKKK cascade ( 0.00657112954497519 ); GO:0051092 positive regulation of NF-kappaB transcription factor activity ( 0.004857532445722 ); GO:0002757 immune response-activating signal transduction ( 0.00657112954497519 ); GO:0002764 immune response-regulating signal transduction ( 0.004857532445722 ); GO:0051704 multi-organism process ( 0.00657112954497519 ); GO:0030595 leukocyte chemotaxis ( 0.004857532445722 ); GO:0060326 cell chemotaxis ( 0.00657112954497519 ); GO:0003704 specific RNA polymerase II transcription factor activity ( 0.004857532445722 ); ----------------GO-------------- GO:0031349 positive regulation of defense response ( 6.18421545143644e-05 ); GO:0019221 cytokine-mediated signaling pathway ( 0.000103757763017703 ); GO:0031347 regulation of defense response ( 0.000249086031391523 ); GO:0016338 calcium-independent cell-cell adhesion ( 0.000301613632936237 ); GO:0050902 leukocyte adhesive activation ( 0.000301613632936237 ); GO:0051040 regulation of calcium-independent cell-cell adhesion ( 0.000301613632936237 ); GO:0051041 positive regulation of calcium-independent cell-cell adhesion ( 0.000301613632936237 ); GO:0006357 regulation of transcription from RNA polymerase II promoter ( 0.000364124832705186 ); GO:0009615 response to virus ( 0.000377801344804649 ); GO:0002238 response to molecule of fungal origin ( 0.000603151453075101 ); GO:0008063 Toll signaling pathway ( 0.000603151453075101 ); GO:0003938 IMP dehydrogenase activity ( 0.000603151453075101 ); GO:0048584 positive regulation of response to stimulus ( 0.00065388287875183 ); GO:0006366 transcription from RNA polymerase II promoter ( 0.000781369692726637 ); GO:0002755 MyD88-dependent toll-like receptor signaling pathway ( 0.000904613475662286 ); GO:0006177 GMP biosynthetic process ( 0.000904613475662286 ); GO:0046037 GMP metabolic process ( 0.000904613475662286 ); GO:0005121 Toll binding ( 0.000904613475662286 ); GO:0051707 response to other organism ( 0.00160266651263745 ); GO:0002221 pattern recognition receptor signaling pathway ( 0.00180854491053573 ); GO:0002224 toll-like receptor signaling pathway ( 0.00180854491053573 ); GO:0048583 regulation of response to stimulus ( 0.00207139278871136 ); GO:0002218 activation of innate immune response ( 0.00210970389532639 ); GO:0002758 innate immune response-activating signal transduction ( 0.00210970389532639 ); GO:0022409 positive regulation of cell-cell adhesion ( 0.00210970389532639 ); GO:0032760 positive regulation of tumor necrosis factor production ( 0.00210970389532639 ); GO:0045080 positive regulation of chemokine biosynthetic process ( 0.00210970389532639 ); GO:0003785 actin monomer binding ( 0.00210970389532639 ); GO:0005123 death receptor binding ( 0.00210970389532639 ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( 0.00241078715875942 ); GO:0045073 regulation of chemokine biosynthetic process ( 0.00241078715875942 ); GO:0045123 cellular extravasation ( 0.00241078715875942 ); GO:0045351 type I interferon biosynthetic process ( 0.00241078715875942 ); GO:0032606 type I interferon production ( 0.0027117947160662 ); GO:0042033 chemokine biosynthetic process ( 0.0027117947160662 ); GO:0050755 chemokine metabolic process ( 0.0027117947160662 ); GO:0046330 positive regulation of JNK cascade ( 0.00301272658247675 ); GO:0009607 response to biotic stimulus ( 0.00322401364591989 ); GO:0006954 inflammatory response ( 0.00343975353783456 ); GO:0032642 regulation of chemokine production ( 0.00361436330351461 ); GO:0032602 chemokine production ( 0.00391506818858967 ); GO:0050896 response to stimulus ( 0.00427048163404294 ); GO:0022407 regulation of cell-cell adhesion ( 0.00451625108395437 ); GO:0046328 regulation of JNK cascade ( 0.00451625108395437 ); GO:0009126 purine nucleoside monophosphate metabolic process ( 0.00481672912467745 ); GO:0009127 purine nucleoside monophosphate biosynthetic process ( 0.00481672912467745 ); GO:0009167 purine ribonucleoside monophosphate metabolic process ( 0.00481672912467745 ); GO:0009168 purine ribonucleoside monophosphate biosynthetic process ( 0.00481672912467745 ); GO:0048661 positive regulation of smooth muscle cell proliferation ( 0.00481672912467745 ); GO:0009620 response to fungus ( 0.00541745846827335 ); GO:0032496 response to lipopolysaccharide ( 0.00571770980156594 ); GO:0050729 positive regulation of inflammatory response ( 0.00601788559613137 ); GO:0032680 regulation of tumor necrosis factor production ( 0.00631798586717336 ); GO:0009156 ribonucleoside monophosphate biosynthetic process ( 0.00661801062989487 ); GO:0009161 ribonucleoside monophosphate metabolic process ( 0.00661801062989487 ); GO:0032640 tumor necrosis factor production ( 0.00661801062989487 ); GO:0045089 positive regulation of innate immune response ( 0.00661801062989487 ); GO:0009123 nucleoside monophosphate metabolic process ( 0.0069179598994944 ); GO:0009124 nucleoside monophosphate biosynthetic process ( 0.0069179598994944 ); GO:0009611 response to wounding ( 0.00705572879204007 ); GO:0002237 response to molecule of bacterial origin ( 0.00721783369117057 ); GO:0048660 regulation of smooth muscle cell proliferation ( 0.00721783369117057 ); GO:0048659 smooth muscle cell proliferation ( 0.0075176320201179 ); GO:0045088 regulation of innate immune response ( 0.00781735490152924 ); GO:0045785 positive regulation of cell adhesion ( 0.00781735490152924 ); GO:0043410 positive regulation of MAPKKK cascade ( 0.00841657438250376 ); GO:0051092 positive regulation of NF-kappaB transcription factor activity ( 0.00841657438250376 ); GO:0002757 immune response-activating signal transduction ( 0.0087160710124411 ); GO:0002764 immune response-regulating signal transduction ( 0.00901549225559073 ); GO:0051704 multi-organism process ( 0.00946948183278429 ); GO:0030595 leukocyte chemotaxis ( 0.00961410864225021 ); GO:0060326 cell chemotaxis ( 0.00961410864225021 ); GO:0003704 specific RNA polymerase II transcription factor activity ( 0.00961410864225021 ); ----------------KEGG-------------- hsa04620 Toll-like receptor signaling pathway ( 0.000370369885126089 ); hsa00983 Drug metabolism - other enzymes ( 0.0131994825443676 ); hsa04210 Apoptosis ( 0.0262534559535107 ); hsa00230 Purine metabolism ( 0.0435315214848334 ); ----------------CARTA-------------- relapathway ( 0.00150731018915273 ); il3pathway ( 0.00391506818858967 ); mprpathway ( 0.00451625108395437 ); nfkbpathway ( 0.00511713158104687 ); il10pathway ( 0.00721783369117057 ); ptenpathway ( 0.00781735490152924 ); ptdinspathway ( 0.00841657438250376 ); metpathway ( 0.0131994825443676 ); fcer1pathway ( 0.0146901925632592 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3683 ========================= ----------------C2-------------- ( 0.00361436330351461 ); ----------------C3-------------- ( 0.00541745846827335 ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00331358277321803 ); ----------------GOSLIM-------------- GO:0051378 serotonin binding ( ); GO:0004993 serotonin receptor activity ( ); GO:0009636 response to toxin ( ); ----------------GO-------------- GO:0051378 serotonin binding ( 0.000301613632936237 ); GO:0004993 serotonin receptor activity ( 0.00361436330351461 ); GO:0009636 response to toxin ( 0.0087160710124411 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3695 ========================= ----------------C2-------------- REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS ( 0.00421569744366346 ); REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT ( 0.0069179598994944 ); REACTOME_RNA_POL_II_CTD_PHOSPHORYLATION_AND_INTERACTION_WITH_CE ( 0.00781735490152924 ); REACTOME_TAT_MEDIATED_HIV1_ELONGATION_ARREST_AND_RECOVERY ( 0.00901549225559073 ); REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX ( 0.00961410864225021 ); REACTOME_MRNA_PROCESSING ( 0.00961410864225021 ); ----------------C3-------------- ( 0.00661801062989487 ); ----------------C4-------------- module_318 ( 0.00841657438250376 ); module_229 ( 0.00931483812713418 ); ----------------C5-------------- RNA_ELONGATION ( 0.00301272658247675 ); TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER ( 0.0087160710124411 ); GENERAL_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY ( 0.00961410864225021 ); ----------------GOSLIM-------------- GO:0070013 intracellular organelle lumen ( ); GO:0043233 organelle lumen ( ); GO:0031974 membrane-enclosed lumen ( ); GO:0005674 transcription factor TFIIF complex ( ); GO:0042769 DNA damage response, detection of DNA damage ( ); GO:0043043 peptide biosynthetic process ( ); GO:0031981 nuclear lumen ( ); GO:0000314 organellar small ribosomal subunit ( ); GO:0005763 mitochondrial small ribosomal subunit ( ); GO:0044451 nucleoplasm part ( ); GO:0006518 peptide metabolic process ( ); GO:0044428 nuclear part ( ); ----------------GO-------------- GO:0070013 intracellular organelle lumen ( 0.000320242695331333 ); GO:0043233 organelle lumen ( 0.000349779573183575 ); GO:0031974 membrane-enclosed lumen ( 0.000380253390691227 ); GO:0005674 transcription factor TFIIF complex ( 0.000603151453075101 ); GO:0042769 DNA damage response, detection of DNA damage ( 0.00150731018915273 ); GO:0043043 peptide biosynthetic process ( 0.00241078715875942 ); GO:0031981 nuclear lumen ( 0.00317058205312197 ); GO:0000314 organellar small ribosomal subunit ( 0.00481672912467745 ); GO:0005763 mitochondrial small ribosomal subunit ( 0.00481672912467745 ); GO:0044451 nucleoplasm part ( 0.00627648737278352 ); GO:0006518 peptide metabolic process ( 0.00631798586717336 ); GO:0044428 nuclear part ( 0.0066913278871328 ); ----------------KEGG-------------- hsa03022 Basal transcription factors ( 0.00991330381611599 ); hsa04115 p53 signaling pathway ( 0.0200412198943029 ); hsa04120 Ubiquitin mediated proteolysis ( 0.0388713951895687 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3703 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00301272658247675 ); ----------------C4-------------- module_205 ( 0.00242839579070082 ); module_424 ( 0.00541745846827335 ); module_478 ( 0.00571770980156594 ); module_5 ( 0.00618933478431562 ); GNF2_TNFSF10 ( 0.00901549225559073 ); GCM_TEC ( 0.00961410864225021 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0045599 negative regulation of fat cell differentiation ( ); GO:0016564 transcription repressor activity ( ); GO:0019864 IgG binding ( ); GO:0045598 regulation of fat cell differentiation ( ); GO:0019865 immunoglobulin binding ( ); GO:0005730 nucleolus ( ); ----------------GO-------------- GO:0045599 negative regulation of fat cell differentiation ( 0.00150731018915273 ); GO:0016564 transcription repressor activity ( 0.00190319345960345 ); GO:0019864 IgG binding ( 0.00241078715875942 ); GO:0045598 regulation of fat cell differentiation ( 0.00301272658247675 ); GO:0019865 immunoglobulin binding ( 0.00451625108395437 ); GO:0005730 nucleolus ( 0.00884373260734779 ); ----------------KEGG-------------- ( 0.0374112314699058 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3732 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00616041136586394 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0032794 GTPase activating protein binding ( ); GO:0017048 Rho GTPase binding ( ); GO:0004693 cyclin-dependent protein kinase activity ( ); ----------------GO-------------- GO:0032794 GTPase activating protein binding ( 0.000603151453075101 ); GO:0017048 Rho GTPase binding ( 0.00721783369117057 ); GO:0004693 cyclin-dependent protein kinase activity ( 0.0087160710124411 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- TDP-43_iCLIP_(Tollervey_2011) ( 0.00678254722352805 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0137489068102899 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0295271668786711 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3791 ========================= ----------------C2-------------- ( 0.00721783369117057 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.0069179598994944 ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( 0.00631798586717336 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3884 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- INSOLUBLE_FRACTION ( 0.00421569744366346 ); PDZ_DOMAIN_BINDING ( 0.00421569744366346 ); REGULATION_OF_PROTEIN_STABILITY ( 0.00571770980156594 ); PROTEIN_HOMOOLIGOMERIZATION ( 0.00661801062989487 ); REGULATION_OF_PROTEIN_AMINO_ACID_PHOSPHORYLATION ( 0.00901549225559073 ); ----------------GOSLIM-------------- GO:0031648 protein destabilization ( ); GO:0004982 N-formyl peptide receptor activity ( ); GO:0043621 protein self-association ( ); GO:0004709 MAP kinase kinase kinase activity ( ); GO:0006464 protein modification process ( ); GO:0043412 biopolymer modification ( ); GO:0030165 PDZ domain binding ( ); ----------------GO-------------- GO:0031648 protein destabilization ( 0.000904613475662286 ); GO:0004982 N-formyl peptide receptor activity ( 0.00180854491053573 ); GO:0043621 protein self-association ( 0.00241078715875942 ); GO:0004709 MAP kinase kinase kinase activity ( 0.00451625108395437 ); GO:0006464 protein modification process ( 0.00534903686880501 ); GO:0043412 biopolymer modification ( 0.00605126756974802 ); GO:0030165 PDZ domain binding ( 0.0081170023505952 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group790 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_562 ( 0.00526763491852544 ); GNF2_CDKN1C ( 0.00676858882979892 ); GNF2_EGFR ( 0.00801799922829738 ); module_511 ( 0.00851741119309746 ); GNF2_IGFBP1 ( 0.00876704173562382 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0032695 negative regulation of interleukin-12 production ( ); GO:0009986 cell surface ( ); GO:0032733 positive regulation of interleukin-10 production ( ); GO:0032613 interleukin-10 production ( ); GO:0032653 regulation of interleukin-10 production ( ); GO:0008191 metalloendopeptidase inhibitor activity ( ); GO:0032615 interleukin-12 production ( ); GO:0032655 regulation of interleukin-12 production ( ); GO:0001818 negative regulation of cytokine production ( ); GO:0050868 negative regulation of T cell activation ( ); GO:0051250 negative regulation of lymphocyte activation ( ); GO:0051239 regulation of multicellular organismal process ( ); GO:0002695 negative regulation of leukocyte activation ( ); GO:0050866 negative regulation of cell activation ( ); ----------------GO-------------- GO:0032695 negative regulation of interleukin-12 production ( 0.00100507555575524 ); GO:0009986 cell surface ( 0.00116971303254507 ); GO:0032733 positive regulation of interleukin-10 production ( 0.00125621812814281 ); GO:0032613 interleukin-10 production ( 0.00200934280751552 ); GO:0032653 regulation of interleukin-10 production ( 0.00200934280751552 ); GO:0008191 metalloendopeptidase inhibitor activity ( 0.00251117347179275 ); GO:0032615 interleukin-12 production ( 0.00276201309019264 ); GO:0032655 regulation of interleukin-12 production ( 0.00276201309019264 ); GO:0001818 negative regulation of cytokine production ( 0.00551791983325034 ); GO:0050868 negative regulation of T cell activation ( 0.00551791983325034 ); GO:0051250 negative regulation of lymphocyte activation ( 0.00776821779082648 ); GO:0051239 regulation of multicellular organismal process ( 0.00838334269389571 ); GO:0002695 negative regulation of leukocyte activation ( 0.00851741119309746 ); GO:0050866 negative regulation of cell activation ( 0.00951563169487812 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.0105130480313538 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group1855 ========================= ----------------C2-------------- REACTOME_CLASS_C3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS ( 0.00376486698322764 ); REACTOME_SIGNALING_BY_ROBO_RECEPTOR ( 0.00776821779082648 ); KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM ( 0.00801799922829738 ); ----------------C3-------------- AGCYRWTTC_UNKNOWN ( 0.000154517326636129 ); V$HNF6_Q6 ( 0.000808607889608138 ); TTTGTAG,MIR-520D ( 0.0019195569499335 ); TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P ( 0.0057405370172841 ); GGCAGAC,MIR-346 ( 0.00801799922829738 ); ----------------C4-------------- GNF2_MATK ( 0.00551791983325034 ); GNF2_SNRK ( 0.00576815436602829 ); GNF2_CASP8 ( 0.00601833852446665 ); GNF2_ZAP70 ( 0.00601833852446665 ); GNF2_JAK1 ( 0.00701857156693042 ); module_202 ( 0.00701857156693042 ); GNF2_RAB7L1 ( 0.00726850396774359 ); GNF2_RAP1B ( 0.00801799922829738 ); GNF2_RAB3A ( 0.00851741119309746 ); GNF2_CD7 ( 0.00926615197891789 ); ----------------C5-------------- METABOTROPIC_GLUTAMATE__GABA_B_LIKE_RECEPTOR_ACTIVITY ( 0.00251117347179275 ); GLUTAMATE_RECEPTOR_ACTIVITY ( 0.00501729961424691 ); ----------------GOSLIM-------------- GO:0001640 adenylate cyclase inhibiting metabotropic glutamate receptor activity ( ); GO:0001641 group II metabotropic glutamate receptor activity ( ); GO:0043197 dendritic spine ( ); GO:0014069 postsynaptic density ( ); GO:0005246 calcium channel regulator activity ( ); GO:0042734 presynaptic membrane ( ); GO:0008066 glutamate receptor activity ( ); GO:0007194 negative regulation of adenylate cyclase activity ( ); GO:0031280 negative regulation of cyclase activity ( ); GO:0051350 negative regulation of lyase activity ( ); ----------------GO-------------- GO:0001640 adenylate cyclase inhibiting metabotropic glutamate receptor activity ( 0.000251344694113254 ); GO:0001641 group II metabotropic glutamate receptor activity ( 0.000251344694113254 ); GO:0043197 dendritic spine ( 0.003012802242921 ); GO:0014069 postsynaptic density ( 0.00326354093759351 ); GO:0005246 calcium channel regulator activity ( 0.00326354093759351 ); GO:0042734 presynaptic membrane ( 0.00376486698322764 ); GO:0008066 glutamate receptor activity ( 0.00751838603984234 ); GO:0007194 negative regulation of adenylate cyclase activity ( 0.00801799922829738 ); GO:0031280 negative regulation of cyclase activity ( 0.00801799922829738 ); GO:0051350 negative regulation of lyase activity ( 0.00801799922829738 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group2150 ========================= ----------------C2-------------- REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY ( 0.00476691391280593 ); REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC ( 0.00551791983325034 ); REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC ( 0.00701857156693042 ); ----------------C3-------------- ( 0.006268472316171 ); ----------------C4-------------- module_391 ( 0.00150731018915273 ); module_315 ( 0.00376486698322764 ); module_543 ( 0.00401545434941553 ); module_346 ( 0.00426599128800043 ); module_408 ( 0.00451647780659392 ); module_424 ( 0.00451647780659392 ); module_478 ( 0.00476691391280593 ); module_253 ( 0.00526763491852544 ); module_417 ( 0.00526763491852544 ); module_196 ( 0.00576815436602829 ); module_367 ( 0.00676858882979892 ); module_522 ( 0.00801799922829738 ); module_96 ( 0.00876704173562382 ); module_410 ( 0.00876704173562382 ); ----------------C5-------------- INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHODIESTERASE_ACTIVITY ( 0.00326354093759351 ); PHOSPHOLIPASE_C_ACTIVITY ( 0.00376486698322764 ); SUGAR_BINDING ( 0.00826773035985462 ); PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0032794 GTPase activating protein binding ( ); GO:0019863 IgE binding ( ); GO:0019865 immunoglobulin binding ( ); GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( ); GO:0004435 phosphoinositide phospholipase C activity ( ); GO:0004629 phospholipase C activity ( ); ----------------GO-------------- GO:0032794 GTPase activating protein binding ( 0.000502638846362036 ); GO:0019863 IgE binding ( 0.00125621812814281 ); GO:0019865 immunoglobulin binding ( 0.00376486698322764 ); GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity ( 0.006268472316171 ); GO:0004435 phosphoinositide phospholipase C activity ( 0.006268472316171 ); GO:0004629 phospholipase C activity ( 0.00751838603984234 ); ----------------KEGG-------------- hsa00562 Inositol phosphate metabolism ( 0.0120076657891357 ); hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.012754297075905 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.012754297075905 ); hsa04070 Phosphatidylinositol signaling system ( 0.0189586873395312 ); hsa04540 Gap junction ( 0.0238997063361746 ); hsa04020 Calcium signaling pathway ( 0.0439501834482882 ); ----------------CARTA-------------- ( 0.00926615197891789 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3014 ========================= ----------------C2-------------- REACTOME_STEROID_HORMONE_BIOSYNTHESIS ( 0.00351422918182454 ); REACTOME_STEROID_HORMONES ( 0.00526763491852544 ); ----------------C3-------------- ( ); ----------------C4-------------- module_120 ( 0.000128278119745175 ); module_557 ( 0.00251117347179275 ); module_470 ( 0.00351422918182454 ); module_489 ( 0.00751838603984234 ); ----------------C5-------------- ( 0.00751838603984234 ); ----------------GOSLIM-------------- GO:0010288 response to lead ion ( ); GO:0005415 nucleoside:sodium symporter activity ( ); GO:0006699 bile acid biosynthetic process ( ); GO:0005215 transporter activity ( ); GO:0015858 nucleoside transport ( ); GO:0005337 nucleoside transmembrane transporter activity ( ); GO:0001882 nucleoside binding ( ); GO:0032869 cellular response to insulin stimulus ( ); GO:0017127 cholesterol transporter activity ( ); GO:0008211 glucocorticoid metabolic process ( ); GO:0015248 sterol transporter activity ( ); GO:0016918 retinal binding ( ); GO:0019841 retinol binding ( ); GO:0050810 regulation of steroid biosynthetic process ( ); GO:0006700 C21-steroid hormone biosynthetic process ( ); GO:0008206 bile acid metabolic process ( ); GO:0015932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity ( ); GO:0032870 cellular response to hormone stimulus ( ); GO:0048168 regulation of neuronal synaptic plasticity ( ); GO:0015485 cholesterol binding ( ); GO:0045768 positive regulation of anti-apoptosis ( ); GO:0008289 lipid binding ( ); GO:0008207 C21-steroid hormone metabolic process ( ); GO:0032868 response to insulin stimulus ( ); GO:0045767 regulation of anti-apoptosis ( ); GO:0005501 retinoid binding ( ); GO:0019840 isoprenoid binding ( ); GO:0045471 response to ethanol ( ); GO:0019218 regulation of steroid metabolic process ( ); GO:0046890 regulation of lipid biosynthetic process ( ); GO:0032934 sterol binding ( ); GO:0048167 regulation of synaptic plasticity ( ); GO:0014070 response to organic cyclic substance ( ); GO:0042542 response to hydrogen peroxide ( ); GO:0050769 positive regulation of neurogenesis ( ); GO:0005758 mitochondrial intermembrane space ( ); GO:0010720 positive regulation of cell development ( ); GO:0031970 organelle envelope lumen ( ); GO:0042446 hormone biosynthetic process ( ); GO:0043434 response to peptide hormone stimulus ( ); ----------------GO-------------- GO:0010288 response to lead ion ( 0.000502638846362036 ); GO:0005415 nucleoside:sodium symporter activity ( 0.000753882464368472 ); GO:0006699 bile acid biosynthetic process ( 0.00125621812814281 ); GO:0005215 transporter activity ( 0.00165918768938662 ); GO:0015858 nucleoside transport ( 0.00175835174640371 ); GO:0005337 nucleoside transmembrane transporter activity ( 0.00200934280751552 ); GO:0001882 nucleoside binding ( 0.00226028338010609 ); GO:0032869 cellular response to insulin stimulus ( 0.00251117347179275 ); GO:0017127 cholesterol transporter activity ( 0.00251117347179275 ); GO:0008211 glucocorticoid metabolic process ( 0.00276201309019264 ); GO:0015248 sterol transporter activity ( 0.003012802242921 ); GO:0016918 retinal binding ( 0.003012802242921 ); GO:0019841 retinol binding ( 0.003012802242921 ); GO:0050810 regulation of steroid biosynthetic process ( 0.00326354093759351 ); GO:0006700 C21-steroid hormone biosynthetic process ( 0.00351422918182454 ); GO:0008206 bile acid metabolic process ( 0.00351422918182454 ); GO:0015932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity ( 0.00351422918182454 ); GO:0032870 cellular response to hormone stimulus ( 0.00376486698322764 ); GO:0048168 regulation of neuronal synaptic plasticity ( 0.00376486698322764 ); GO:0015485 cholesterol binding ( 0.00376486698322764 ); GO:0045768 positive regulation of anti-apoptosis ( 0.00401545434941553 ); GO:0008289 lipid binding ( 0.0044237441495251 ); GO:0008207 C21-steroid hormone metabolic process ( 0.00476691391280593 ); GO:0032868 response to insulin stimulus ( 0.00476691391280593 ); GO:0045767 regulation of anti-apoptosis ( 0.00476691391280593 ); GO:0005501 retinoid binding ( 0.00476691391280593 ); GO:0019840 isoprenoid binding ( 0.00476691391280593 ); GO:0045471 response to ethanol ( 0.00501729961424691 ); GO:0019218 regulation of steroid metabolic process ( 0.00526763491852544 ); GO:0046890 regulation of lipid biosynthetic process ( 0.00551791983325034 ); GO:0032934 sterol binding ( 0.00551791983325034 ); GO:0048167 regulation of synaptic plasticity ( 0.006268472316171 ); GO:0014070 response to organic cyclic substance ( 0.00651855574874693 ); GO:0042542 response to hydrogen peroxide ( 0.00701857156693042 ); GO:0050769 positive regulation of neurogenesis ( 0.00701857156693042 ); GO:0005758 mitochondrial intermembrane space ( 0.00701857156693042 ); GO:0010720 positive regulation of cell development ( 0.00776821779082648 ); GO:0031970 organelle envelope lumen ( 0.00801799922829738 ); GO:0042446 hormone biosynthetic process ( 0.00876704173562382 ); GO:0043434 response to peptide hormone stimulus ( 0.00951563169487812 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3056 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00976506115050757 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3098 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_563 ( 0.00351422918182454 ); module_186 ( 0.00501729961424691 ); module_284 ( 0.00901662199503184 ); GNF2_MAPT ( 0.00951563169487812 ); ----------------C5-------------- L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00426599128800043 ); REGULATION_OF_NEUROTRANSMITTER_LEVELS ( 0.00601833852446665 ); AMINO_ACID_TRANSPORT ( 0.00651855574874693 ); AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00726850396774359 ); AMINE_TRANSPORT ( 0.00951563169487812 ); ----------------GOSLIM-------------- GO:0031223 auditory behavior ( ); GO:0005314 high-affinity glutamate transmembrane transporter activity ( ); GO:0005641 nuclear envelope lumen ( ); GO:0016595 glutamate binding ( ); GO:0043205 fibril ( ); GO:0007638 mechanosensory behavior ( ); GO:0017153 sodium:dicarboxylate symporter activity ( ); GO:0005313 L-glutamate transmembrane transporter activity ( ); GO:0015172 acidic amino acid transmembrane transporter activity ( ); GO:0006835 dicarboxylic acid transport ( ); GO:0005310 dicarboxylic acid transmembrane transporter activity ( ); GO:0001504 neurotransmitter uptake ( ); GO:0050806 positive regulation of synaptic transmission ( ); GO:0015800 acidic amino acid transport ( ); GO:0015813 L-glutamate transport ( ); GO:0021545 cranial nerve development ( ); GO:0051971 positive regulation of transmission of nerve impulse ( ); GO:0006536 glutamate metabolic process ( ); GO:0031646 positive regulation of neurological system process ( ); GO:0016597 amino acid binding ( ); GO:0021675 nerve development ( ); GO:0005343 organic acid:sodium symporter activity ( ); GO:0050885 neuromuscular process controlling balance ( ); GO:0015296 anion:cation symporter activity ( ); GO:0009612 response to mechanical stimulus ( ); GO:0031970 organelle envelope lumen ( ); GO:0015179 L-amino acid transmembrane transporter activity ( ); ----------------GO-------------- GO:0031223 auditory behavior ( 0.000251344694113254 ); GO:0005314 high-affinity glutamate transmembrane transporter activity ( 0.000251344694113254 ); GO:0005641 nuclear envelope lumen ( 0.00100507555575524 ); GO:0016595 glutamate binding ( 0.00100507555575524 ); GO:0043205 fibril ( 0.00175835174640371 ); GO:0007638 mechanosensory behavior ( 0.00200934280751552 ); GO:0017153 sodium:dicarboxylate symporter activity ( 0.00200934280751552 ); GO:0005313 L-glutamate transmembrane transporter activity ( 0.00276201309019264 ); GO:0015172 acidic amino acid transmembrane transporter activity ( 0.00276201309019264 ); GO:0006835 dicarboxylic acid transport ( 0.003012802242921 ); GO:0005310 dicarboxylic acid transmembrane transporter activity ( 0.003012802242921 ); GO:0001504 neurotransmitter uptake ( 0.00326354093759351 ); GO:0050806 positive regulation of synaptic transmission ( 0.00326354093759351 ); GO:0015800 acidic amino acid transport ( 0.00351422918182454 ); GO:0015813 L-glutamate transport ( 0.00351422918182454 ); GO:0021545 cranial nerve development ( 0.00351422918182454 ); GO:0051971 positive regulation of transmission of nerve impulse ( 0.00351422918182454 ); GO:0006536 glutamate metabolic process ( 0.00376486698322764 ); GO:0031646 positive regulation of neurological system process ( 0.00376486698322764 ); GO:0016597 amino acid binding ( 0.00476691391280593 ); GO:0021675 nerve development ( 0.00501729961424691 ); GO:0005343 organic acid:sodium symporter activity ( 0.00551791983325034 ); GO:0050885 neuromuscular process controlling balance ( 0.00651855574874693 ); GO:0015296 anion:cation symporter activity ( 0.00651855574874693 ); GO:0009612 response to mechanical stimulus ( 0.00726850396774359 ); GO:0031970 organelle envelope lumen ( 0.00801799922829738 ); GO:0015179 L-amino acid transmembrane transporter activity ( 0.00851741119309746 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3099 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_25 ( 0.00326354093759351 ); module_42 ( 0.006268472316171 ); module_77 ( 0.00701857156693042 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005740 mitochondrial envelope ( ); GO:0048738 cardiac muscle development ( ); GO:0051537 2 iron, 2 sulfur cluster binding ( ); GO:0044429 mitochondrial part ( ); GO:0005758 mitochondrial intermembrane space ( ); GO:0031967 organelle envelope ( ); GO:0031975 envelope ( ); GO:0031970 organelle envelope lumen ( ); GO:0051287 NAD or NADH binding ( ); GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( ); GO:0005747 mitochondrial respiratory chain complex I ( ); GO:0030964 NADH dehydrogenase complex ( ); GO:0045271 respiratory chain complex I ( ); GO:0003954 NADH dehydrogenase activity ( ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( ); GO:0050136 NADH dehydrogenase (quinone) activity ( ); ----------------GO-------------- GO:0005740 mitochondrial envelope ( 0.0031672538000509 ); GO:0048738 cardiac muscle development ( 0.00351422918182454 ); GO:0051537 2 iron, 2 sulfur cluster binding ( 0.00401545434941553 ); GO:0044429 mitochondrial part ( 0.00625521314582036 ); GO:0005758 mitochondrial intermembrane space ( 0.00701857156693042 ); GO:0031967 organelle envelope ( 0.00734694124840342 ); GO:0031975 envelope ( 0.00737271275501804 ); GO:0031970 organelle envelope lumen ( 0.00801799922829738 ); GO:0051287 NAD or NADH binding ( 0.00826773035985462 ); GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( 0.00901662199503184 ); GO:0005747 mitochondrial respiratory chain complex I ( 0.00901662199503184 ); GO:0030964 NADH dehydrogenase complex ( 0.00901662199503184 ); GO:0045271 respiratory chain complex I ( 0.00901662199503184 ); GO:0003954 NADH dehydrogenase activity ( 0.00926615197891789 ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( 0.00926615197891789 ); GO:0050136 NADH dehydrogenase (quinone) activity ( 0.00926615197891789 ); ----------------KEGG-------------- hsa05012 Parkinson's disease ( 0.0280839013614591 ); hsa00190 Oxidative phosphorylation ( 0.0283295828828541 ); hsa05322 Systemic lupus erythematosus ( 0.0312738878389577 ); hsa05010 Alzheimer's disease ( 0.039333941311084 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3120 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- COENZYME_BINDING ( 0.00401545434941553 ); COFACTOR_BINDING ( 0.00551791983325034 ); ----------------GOSLIM-------------- GO:0030586 [methionine synthase] reductase activity ( ); GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor ( ); GO:0016722 oxidoreductase activity, oxidizing metal ions ( ); GO:0009086 methionine biosynthetic process ( ); GO:0006555 methionine metabolic process ( ); GO:0010181 FMN binding ( ); GO:0000097 sulfur amino acid biosynthetic process ( ); GO:0009067 aspartate family amino acid biosynthetic process ( ); GO:0000096 sulfur amino acid metabolic process ( ); GO:0009066 aspartate family amino acid metabolic process ( ); GO:0001608 nucleotide receptor activity, G-protein coupled ( ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( ); GO:0050661 NADP or NADPH binding ( ); GO:0001614 purinergic nucleotide receptor activity ( ); GO:0016502 nucleotide receptor activity ( ); ----------------GO-------------- GO:0030586 [methionine synthase] reductase activity ( 0.000251344694113254 ); GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor ( 0.00100507555575524 ); GO:0016722 oxidoreductase activity, oxidizing metal ions ( 0.00175835174640371 ); GO:0009086 methionine biosynthetic process ( 0.00226028338010609 ); GO:0006555 methionine metabolic process ( 0.003012802242921 ); GO:0010181 FMN binding ( 0.003012802242921 ); GO:0000097 sulfur amino acid biosynthetic process ( 0.00376486698322764 ); GO:0009067 aspartate family amino acid biosynthetic process ( 0.00376486698322764 ); GO:0000096 sulfur amino acid metabolic process ( 0.00526763491852544 ); GO:0009066 aspartate family amino acid metabolic process ( 0.00526763491852544 ); GO:0001608 nucleotide receptor activity, G-protein coupled ( 0.00676858882979892 ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( 0.00676858882979892 ); GO:0050661 NADP or NADPH binding ( 0.00701857156693042 ); GO:0001614 purinergic nucleotide receptor activity ( 0.00851741119309746 ); GO:0016502 nucleotide receptor activity ( 0.00851741119309746 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3136 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ACTWSNACTNY_UNKNOWN ( 8.89385152497431e-05 ); TGGTGCT,MIR-29A,MIR-29B,MIR-29C ( 0.00454601779457308 ); ----------------C4-------------- ( 0.00801799922829738 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0042627 chylomicron ( ); GO:0032994 protein-lipid complex ( ); GO:0034358 plasma lipoprotein particle ( ); GO:0001889 liver development ( ); ----------------GO-------------- GO:0042627 chylomicron ( 0.003012802242921 ); GO:0032994 protein-lipid complex ( 0.00451647780659392 ); GO:0034358 plasma lipoprotein particle ( 0.00451647780659392 ); GO:0001889 liver development ( 0.00676858882979892 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3141 ========================= ----------------C2-------------- ( 0.00476691391280593 ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_SPRR1B ( 0.00551791983325034 ); module_366 ( 0.00726850396774359 ); module_153 ( 0.00851741119309746 ); ----------------C5-------------- CORNIFIED_ENVELOPE ( 0.00326354093759351 ); POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION ( 0.00326354093759351 ); KERATINOCYTE_DIFFERENTIATION ( 0.00376486698322764 ); REGULATION_OF_T_CELL_PROLIFERATION ( 0.00401545434941553 ); T_CELL_PROLIFERATION ( 0.00476691391280593 ); POSITIVE_REGULATION_OF_T_CELL_ACTIVATION ( 0.00526763491852544 ); POSITIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION ( 0.00576815436602829 ); REGULATION_OF_T_CELL_ACTIVATION ( 0.00701857156693042 ); REGULATION_OF_LYMPHOCYTE_ACTIVATION ( 0.00851741119309746 ); ----------------GOSLIM-------------- GO:0006972 hyperosmotic response ( ); GO:0042104 positive regulation of activated T cell proliferation ( ); GO:0046006 regulation of activated T cell proliferation ( ); GO:0050798 activated T cell proliferation ( ); GO:0006970 response to osmotic stress ( ); GO:0001533 cornified envelope ( ); GO:0018149 peptide cross-linking ( ); GO:0042102 positive regulation of T cell proliferation ( ); GO:0050671 positive regulation of lymphocyte proliferation ( ); GO:0032946 positive regulation of mononuclear cell proliferation ( ); GO:0030216 keratinocyte differentiation ( ); ----------------GO-------------- GO:0006972 hyperosmotic response ( 0.00100507555575524 ); GO:0042104 positive regulation of activated T cell proliferation ( 0.00175835174640371 ); GO:0046006 regulation of activated T cell proliferation ( 0.00226028338010609 ); GO:0050798 activated T cell proliferation ( 0.003012802242921 ); GO:0006970 response to osmotic stress ( 0.00351422918182454 ); GO:0001533 cornified envelope ( 0.00451647780659392 ); GO:0018149 peptide cross-linking ( 0.00476691391280593 ); GO:0042102 positive regulation of T cell proliferation ( 0.00751838603984234 ); GO:0050671 positive regulation of lymphocyte proliferation ( 0.00876704173562382 ); GO:0032946 positive regulation of mononuclear cell proliferation ( 0.00901662199503184 ); GO:0030216 keratinocyte differentiation ( 0.00926615197891789 ); ----------------KEGG-------------- ( 0.0322537351436573 ); ----------------CARTA-------------- ( 0.00751838603984234 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0483070795264641 ); ============================ group3143 ========================= ----------------C2-------------- ( ); ----------------C3-------------- TGACATY_UNKNOWN ( 0.000150202319134112 ); V$PIT1_Q6 ( 0.000808607889608138 ); V$AREB6_02 ( 0.000871925264664222 ); V$AREB6_04 ( 0.000928058992789882 ); V$HEB_Q6 ( 0.000947151528491983 ); TGTTTGY_V$HNF3_Q6 ( 0.00739852669130702 ); ----------------C4-------------- ( 0.00876704173562382 ); ----------------C5-------------- NUCLEOTIDE_KINASE_ACTIVITY ( 0.00326354093759351 ); PHOSPHOTRANSFERASE_ACTIVITY__PHOSPHATE_GROUP_AS_ACCEPTOR ( 0.00451647780659392 ); NUCLEOBASE__NUCLEOSIDE__NUCLEOTIDE_KINASE_ACTIVITY ( 0.00601833852446665 ); ----------------GOSLIM-------------- GO:0004385 guanylate kinase activity ( ); GO:0019201 nucleotide kinase activity ( ); GO:0016776 phosphotransferase activity, phosphate group as acceptor ( ); ----------------GO-------------- GO:0004385 guanylate kinase activity ( 0.00226028338010609 ); GO:0019201 nucleotide kinase activity ( 0.00526763491852544 ); GO:0016776 phosphotransferase activity, phosphate group as acceptor ( 0.00776821779082648 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3145 ========================= ----------------C2-------------- ( 0.00726850396774359 ); ----------------C3-------------- ( ); ----------------C4-------------- module_389 ( 0.000808607889608138 ); module_207 ( 0.000928058992789882 ); ----------------C5-------------- PATTERN_RECOGNITION_RECEPTOR_ACTIVITY ( 0.00251117347179275 ); KINESIN_COMPLEX ( 0.00351422918182454 ); MICROTUBULE_MOTOR_ACTIVITY ( 0.00401545434941553 ); MOTOR_ACTIVITY ( 0.00701857156693042 ); ----------------GOSLIM-------------- GO:0008329 pattern recognition receptor activity ( ); GO:0007030 Golgi organization ( ); GO:0005871 kinesin complex ( ); GO:0004003 ATP-dependent DNA helicase activity ( ); GO:0005044 scavenger receptor activity ( ); GO:0003678 DNA helicase activity ( ); ----------------GO-------------- GO:0008329 pattern recognition receptor activity ( 0.00276201309019264 ); GO:0007030 Golgi organization ( 0.00326354093759351 ); GO:0005871 kinesin complex ( 0.00376486698322764 ); GO:0004003 ATP-dependent DNA helicase activity ( 0.00551791983325034 ); GO:0005044 scavenger receptor activity ( 0.00826773035985462 ); GO:0003678 DNA helicase activity ( 0.00951563169487812 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3147 ========================= ----------------C2-------------- REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS ( 0.00251117347179275 ); REACTOME_P2Y_RECEPTORS ( 0.003012802242921 ); REACTOME_SIGNALING_BY_TGF_BETA ( 0.00376486698322764 ); REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS ( 0.00401545434941553 ); REACTOME_SIGNALING_BY_NOTCH ( 0.00401545434941553 ); ----------------C3-------------- YTTCCNNNGGAMR_UNKNOWN ( 0.00926615197891789 ); CCTGAGT,MIR-510 ( 0.00951563169487812 ); ----------------C4-------------- ( ); ----------------C5-------------- PEPTIDE_METABOLIC_PROCESS ( 0.00251117347179275 ); TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE ( 0.00276201309019264 ); NEGATIVE_REGULATION_OF_TRANSLATION ( 0.00551791983325034 ); GOLGI_ASSOCIATED_VESICLE ( 0.00676858882979892 ); NEGATIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS ( 0.00701857156693042 ); TRANSPORT_VESICLE ( 0.00726850396774359 ); NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS ( 0.00726850396774359 ); CLATHRIN_COATED_VESICLE ( 0.00876704173562382 ); SERINE_TYPE_ENDOPEPTIDASE_ACTIVITY ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0032804 negative regulation of low-density lipoprotein receptor catabolic process ( ); GO:0032899 regulation of neurotrophin production ( ); GO:0032900 negative regulation of neurotrophin production ( ); GO:0032903 regulation of nerve growth factor production ( ); GO:0032904 negative regulation of nerve growth factor production ( ); GO:0032911 negative regulation of transforming growth factor-beta1 production ( ); GO:0032898 neurotrophin production ( ); GO:0032902 nerve growth factor production ( ); GO:0019067 viral assembly, maturation, egress, and release ( ); GO:0032802 low-density lipoprotein receptor catabolic process ( ); GO:0032803 regulation of low-density lipoprotein receptor catabolic process ( ); GO:0032905 transforming growth factor-beta1 production ( ); GO:0032908 regulation of transforming growth factor-beta1 production ( ); GO:0032455 nerve growth factor processing ( ); GO:0032801 receptor catabolic process ( ); GO:0048406 nerve growth factor binding ( ); GO:0006465 signal peptide processing ( ); GO:0031330 negative regulation of cellular catabolic process ( ); GO:0032799 low-density lipoprotein receptor metabolic process ( ); GO:0043043 peptide biosynthetic process ( ); GO:0043121 neurotrophin binding ( ); GO:0051044 positive regulation of membrane protein ectodomain proteolysis ( ); GO:0051043 regulation of membrane protein ectodomain proteolysis ( ); GO:0016486 peptide hormone processing ( ); GO:0045862 positive regulation of proteolysis ( ); GO:0002020 protease binding ( ); GO:0009895 negative regulation of catabolic process ( ); GO:0051605 protein maturation via proteolysis ( ); GO:0030140 trans-Golgi network transport vesicle ( ); GO:0006518 peptide metabolic process ( ); GO:0001818 negative regulation of cytokine production ( ); GO:0042176 regulation of protein catabolic process ( ); GO:0006509 membrane protein ectodomain proteolysis ( ); GO:0031329 regulation of cellular catabolic process ( ); GO:0033619 membrane protein proteolysis ( ); GO:0043524 negative regulation of neuron apoptosis ( ); GO:0005802 trans-Golgi network ( ); GO:0001608 nucleotide receptor activity, G-protein coupled ( ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( ); GO:0043112 receptor metabolic process ( ); GO:0051604 protein maturation ( ); GO:0030162 regulation of proteolysis ( ); GO:0001614 purinergic nucleotide receptor activity ( ); GO:0016502 nucleotide receptor activity ( ); GO:0043523 regulation of neuron apoptosis ( ); ----------------GO-------------- GO:0032804 negative regulation of low-density lipoprotein receptor catabolic process ( 0.000251344694113254 ); GO:0032899 regulation of neurotrophin production ( 0.000251344694113254 ); GO:0032900 negative regulation of neurotrophin production ( 0.000251344694113254 ); GO:0032903 regulation of nerve growth factor production ( 0.000251344694113254 ); GO:0032904 negative regulation of nerve growth factor production ( 0.000251344694113254 ); GO:0032911 negative regulation of transforming growth factor-beta1 production ( 0.000251344694113254 ); GO:0032898 neurotrophin production ( 0.000502638846362036 ); GO:0032902 nerve growth factor production ( 0.000502638846362036 ); GO:0019067 viral assembly, maturation, egress, and release ( 0.000753882464368472 ); GO:0032802 low-density lipoprotein receptor catabolic process ( 0.000753882464368472 ); GO:0032803 regulation of low-density lipoprotein receptor catabolic process ( 0.000753882464368472 ); GO:0032905 transforming growth factor-beta1 production ( 0.000753882464368472 ); GO:0032908 regulation of transforming growth factor-beta1 production ( 0.000753882464368472 ); GO:0032455 nerve growth factor processing ( 0.00100507555575524 ); GO:0032801 receptor catabolic process ( 0.00125621812814281 ); GO:0048406 nerve growth factor binding ( 0.00125621812814281 ); GO:0006465 signal peptide processing ( 0.00175835174640371 ); GO:0031330 negative regulation of cellular catabolic process ( 0.00175835174640371 ); GO:0032799 low-density lipoprotein receptor metabolic process ( 0.00200934280751552 ); GO:0043043 peptide biosynthetic process ( 0.00200934280751552 ); GO:0043121 neurotrophin binding ( 0.00200934280751552 ); GO:0051044 positive regulation of membrane protein ectodomain proteolysis ( 0.00226028338010609 ); GO:0051043 regulation of membrane protein ectodomain proteolysis ( 0.00326354093759351 ); GO:0016486 peptide hormone processing ( 0.00351422918182454 ); GO:0045862 positive regulation of proteolysis ( 0.00376486698322764 ); GO:0002020 protease binding ( 0.00401545434941553 ); GO:0009895 negative regulation of catabolic process ( 0.00476691391280593 ); GO:0051605 protein maturation via proteolysis ( 0.00501729961424691 ); GO:0030140 trans-Golgi network transport vesicle ( 0.00501729961424691 ); GO:0006518 peptide metabolic process ( 0.00526763491852544 ); GO:0001818 negative regulation of cytokine production ( 0.00551791983325034 ); GO:0042176 regulation of protein catabolic process ( 0.00601833852446665 ); GO:0006509 membrane protein ectodomain proteolysis ( 0.006268472316171 ); GO:0031329 regulation of cellular catabolic process ( 0.006268472316171 ); GO:0033619 membrane protein proteolysis ( 0.006268472316171 ); GO:0043524 negative regulation of neuron apoptosis ( 0.00651855574874693 ); GO:0005802 trans-Golgi network ( 0.00676858882979892 ); GO:0001608 nucleotide receptor activity, G-protein coupled ( 0.00676858882979892 ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( 0.00676858882979892 ); GO:0043112 receptor metabolic process ( 0.00701857156693042 ); GO:0051604 protein maturation ( 0.00726850396774359 ); GO:0030162 regulation of proteolysis ( 0.00776821779082648 ); GO:0001614 purinergic nucleotide receptor activity ( 0.00851741119309746 ); GO:0016502 nucleotide receptor activity ( 0.00851741119309746 ); GO:0043523 regulation of neuron apoptosis ( 0.00976506115050757 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3148 ========================= ----------------C2-------------- REACTOME_CITRIC_ACID_CYCLE ( 0.00476691391280593 ); KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM ( 0.00551791983325034 ); REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS ( 0.00726850396774359 ); REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE ( 0.00901662199503184 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- COFACTOR_CATABOLIC_PROCESS ( 0.00251117347179275 ); LYSOSOMAL_TRANSPORT ( 0.00251117347179275 ); VACUOLAR_TRANSPORT ( 0.00326354093759351 ); AEROBIC_RESPIRATION ( 0.00376486698322764 ); COENZYME_BINDING ( 0.00401545434941553 ); CELLULAR_RESPIRATION ( 0.00476691391280593 ); COFACTOR_BINDING ( 0.00551791983325034 ); MITOCHONDRIAL_RESPIRATORY_CHAIN ( 0.00576815436602829 ); OXIDOREDUCTASE_ACTIVITY__ACTING_ON_NADH_OR_NADPH ( 0.00601833852446665 ); HYDROGEN_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00676858882979892 ); MONOVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00826773035985462 ); COENZYME_METABOLIC_PROCESS ( 0.00926615197891789 ); ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity ( 0.00926615197891789 ); GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity ( 0.00926615197891789 ); GO:0008746 NAD(P) transhydrogenase activity ( 0.00926615197891789 ); GO:0016652 oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor ( 0.00926615197891789 ); GO:0006622 protein targeting to lysosome ( 0.00926615197891789 ); GO:0007041 lysosomal transport ( 0.00926615197891789 ); GO:0007034 vacuolar transport ( 0.00926615197891789 ); GO:0006099 tricarboxylic acid cycle ( 0.00926615197891789 ); GO:0046356 acetyl-CoA catabolic process ( 0.00926615197891789 ); GO:0006084 acetyl-CoA metabolic process ( 0.00926615197891789 ); GO:0030131 clathrin adaptor complex ( 0.00926615197891789 ); GO:0009109 coenzyme catabolic process ( 0.00926615197891789 ); GO:0030119 AP-type membrane coat adaptor complex ( 0.00926615197891789 ); GO:0050661 NADP or NADPH binding ( 0.00926615197891789 ); GO:0051187 cofactor catabolic process ( 0.00926615197891789 ); GO:0030118 clathrin coat ( 0.00926615197891789 ); GO:0051287 NAD or NADH binding ( 0.00926615197891789 ); GO:0009060 aerobic respiration ( 0.00926615197891789 ); ----------------GO-------------- GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity ( 0.000251344694113254 ); GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity ( 0.000251344694113254 ); GO:0008746 NAD(P) transhydrogenase activity ( 0.000502638846362036 ); GO:0016652 oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor ( 0.000502638846362036 ); GO:0006622 protein targeting to lysosome ( 0.00150731018915273 ); GO:0007041 lysosomal transport ( 0.00376486698322764 ); GO:0007034 vacuolar transport ( 0.00551791983325034 ); GO:0006099 tricarboxylic acid cycle ( 0.00576815436602829 ); GO:0046356 acetyl-CoA catabolic process ( 0.00576815436602829 ); GO:0006084 acetyl-CoA metabolic process ( 0.006268472316171 ); GO:0030131 clathrin adaptor complex ( 0.006268472316171 ); GO:0009109 coenzyme catabolic process ( 0.00651855574874693 ); GO:0030119 AP-type membrane coat adaptor complex ( 0.00651855574874693 ); GO:0050661 NADP or NADPH binding ( 0.00701857156693042 ); GO:0051187 cofactor catabolic process ( 0.00776821779082648 ); GO:0030118 clathrin coat ( 0.00826773035985462 ); GO:0051287 NAD or NADH binding ( 0.00826773035985462 ); GO:0009060 aerobic respiration ( 0.00851741119309746 ); ----------------KEGG-------------- ( 0.00601833852446665 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3159 ========================= ----------------C2-------------- BIOCARTA_GSK3_PATHWAY ( 0.00676858882979892 ); REACTOME_TOLL_LIKE_RECEPTOR_4_CASCADE ( 0.00701857156693042 ); BIOCARTA_TOLL_PATHWAY ( 0.00876704173562382 ); ----------------C3-------------- ( ); ----------------C4-------------- GNF2_CD14 ( 2.49932292304426e-05 ); GNF2_CD1D ( 4.12820433562874e-05 ); GNF2_CD33 ( 5.20797762556291e-05 ); GNF2_CARD15 ( 9.49993578599959e-05 ); module_12 ( 0.00291359511853682 ); module_1 ( 0.00303070044695511 ); module_328 ( 0.00351422918182454 ); module_84 ( 0.00642335165038737 ); module_300 ( 0.00801799922829738 ); GNF2_FOS ( 0.00876704173562382 ); module_247 ( 0.00876704173562382 ); ----------------C5-------------- NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION ( 0.00251117347179275 ); PATTERN_RECOGNITION_RECEPTOR_ACTIVITY ( 0.00251117347179275 ); SENSORY_ORGAN_DEVELOPMENT ( 0.00351422918182454 ); PHAGOCYTOSIS ( 0.00426599128800043 ); REGULATION_OF_MYELOID_CELL_DIFFERENTIATION ( 0.00476691391280593 ); HOMEOSTASIS_OF_NUMBER_OF_CELLS ( 0.00501729961424691 ); NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION ( 0.00701857156693042 ); MYELOID_CELL_DIFFERENTIATION ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0021572 rhombomere 6 development ( 0.00500793035823826 ); GO:0001847 opsonin receptor activity ( 0.00776821779082648 ); GO:0035283 central nervous system segmentation ( 0.00500793035823826 ); GO:0035284 brain segmentation ( 0.00776821779082648 ); GO:0045647 negative regulation of erythrocyte differentiation ( 0.00500793035823826 ); GO:0021571 rhombomere 5 development ( 0.00776821779082648 ); GO:0046696 lipopolysaccharide receptor complex ( 0.00500793035823826 ); GO:0001846 opsonin binding ( 0.00776821779082648 ); GO:0016019 peptidoglycan receptor activity ( 0.00500793035823826 ); GO:0021546 rhombomere development ( 0.00776821779082648 ); GO:0007379 segment specification ( 0.00500793035823826 ); GO:0042834 peptidoglycan binding ( 0.00776821779082648 ); GO:0008329 pattern recognition receptor activity ( 0.00500793035823826 ); GO:0045646 regulation of erythrocyte differentiation ( 0.00776821779082648 ); GO:0002237 response to molecule of bacterial origin ( 0.00500793035823826 ); GO:0007585 respiratory gaseous exchange ( 0.00776821779082648 ); GO:0045638 negative regulation of myeloid cell differentiation ( 0.00500793035823826 ); GO:0035282 segmentation ( 0.00776821779082648 ); GO:0009880 embryonic pattern specification ( 0.00500793035823826 ); GO:0042472 inner ear morphogenesis ( 0.00776821779082648 ); GO:0030902 hindbrain development ( 0.00500793035823826 ); ----------------GO-------------- GO:0021572 rhombomere 6 development ( 0.000251344694113254 ); GO:0001847 opsonin receptor activity ( 0.000251344694113254 ); GO:0035283 central nervous system segmentation ( 0.000753882464368472 ); GO:0035284 brain segmentation ( 0.000753882464368472 ); GO:0045647 negative regulation of erythrocyte differentiation ( 0.000753882464368472 ); GO:0021571 rhombomere 5 development ( 0.00100507555575524 ); GO:0046696 lipopolysaccharide receptor complex ( 0.00100507555575524 ); GO:0001846 opsonin binding ( 0.00100507555575524 ); GO:0016019 peptidoglycan receptor activity ( 0.00125621812814281 ); GO:0021546 rhombomere development ( 0.00150731018915273 ); GO:0007379 segment specification ( 0.00226028338010609 ); GO:0042834 peptidoglycan binding ( 0.00226028338010609 ); GO:0008329 pattern recognition receptor activity ( 0.00276201309019264 ); GO:0045646 regulation of erythrocyte differentiation ( 0.003012802242921 ); GO:0002237 response to molecule of bacterial origin ( 0.00601833852446665 ); GO:0007585 respiratory gaseous exchange ( 0.00701857156693042 ); GO:0045638 negative regulation of myeloid cell differentiation ( 0.00726850396774359 ); GO:0035282 segmentation ( 0.00801799922829738 ); GO:0009880 embryonic pattern specification ( 0.00826773035985462 ); GO:0042472 inner ear morphogenesis ( 0.00926615197891789 ); GO:0030902 hindbrain development ( 0.00951563169487812 ); ----------------KEGG-------------- hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.012754297075905 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.012754297075905 ); hsa04640 Hematopoietic cell lineage ( 0.0209374902199219 ); hsa04620 Toll-like receptor signaling pathway ( 0.0248855167880806 ); ----------------CARTA-------------- il10pathway ( 0.00601833852446665 ); ptenpathway ( 0.00651855574874693 ); ptdinspathway ( 0.00701857156693042 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3168 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00826773035985462 ); ----------------C4-------------- ( 0.00701857156693042 ); ----------------C5-------------- ( 0.00551791983325034 ); ----------------GOSLIM-------------- GO:0005833 hemoglobin complex ( ); GO:0004886 retinoid-X receptor activity ( ); GO:0010861 thyroid hormone receptor activator activity ( ); GO:0030375 thyroid hormone receptor coactivator activity ( ); GO:0015671 oxygen transport ( ); GO:0005344 oxygen transporter activity ( ); GO:0042974 retinoic acid receptor binding ( ); GO:0003708 retinoic acid receptor activity ( ); GO:0030546 receptor activator activity ( ); GO:0015669 gas transport ( ); GO:0042809 vitamin D receptor binding ( ); GO:0030545 receptor regulator activity ( ); GO:0046966 thyroid hormone receptor binding ( ); GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity ( ); GO:0019825 oxygen binding ( ); ----------------GO-------------- GO:0005833 hemoglobin complex ( 0.00251117347179275 ); GO:0004886 retinoid-X receptor activity ( 0.00251117347179275 ); GO:0010861 thyroid hormone receptor activator activity ( 0.00251117347179275 ); GO:0030375 thyroid hormone receptor coactivator activity ( 0.00251117347179275 ); GO:0015671 oxygen transport ( 0.003012802242921 ); GO:0005344 oxygen transporter activity ( 0.003012802242921 ); GO:0042974 retinoic acid receptor binding ( 0.003012802242921 ); GO:0003708 retinoic acid receptor activity ( 0.00326354093759351 ); GO:0030546 receptor activator activity ( 0.00326354093759351 ); GO:0015669 gas transport ( 0.00351422918182454 ); GO:0042809 vitamin D receptor binding ( 0.00451647780659392 ); GO:0030545 receptor regulator activity ( 0.006268472316171 ); GO:0046966 thyroid hormone receptor binding ( 0.006268472316171 ); GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity ( 0.00676858882979892 ); GO:0019825 oxygen binding ( 0.00801799922829738 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3225 ========================= ----------------C2-------------- REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION ( 2.77728779592239e-06 ); REACTOME_APOPTOTIC_EXECUTION_PHASE ( 5.43889576759431e-05 ); REACTOME_APOPTOSIS ( 0.000405624269656599 ); REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING ( 0.00326354093759351 ); REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES ( 0.00451647780659392 ); ----------------C3-------------- KRCTCNNNNMANAGC_UNKNOWN ( 8.5982555841101e-05 ); TTTNNANAGCYR_UNKNOWN ( 0.000339028266630128 ); V$TATA_01 ( 0.00116971303254507 ); CTAWWWATA_V$RSRFC4_Q2 ( 0.0019195569499335 ); RCGCANGCGY_V$NRF1_Q6 ( 0.00795039584592495 ); ----------------C4-------------- module_203 ( 6.05649040856098e-06 ); module_90 ( 6.8633320564972e-06 ); module_189 ( 1.27601121317443e-05 ); module_127 ( 1.63865017721149e-05 ); module_89 ( 0.00351422918182454 ); module_534 ( 0.00376486698322764 ); module_102 ( 0.00451647780659392 ); module_552 ( 0.00451647780659392 ); module_168 ( 0.00551791983325034 ); module_222 ( 0.00551791983325034 ); module_421 ( 0.00576815436602829 ); module_219 ( 0.00651855574874693 ); module_116 ( 0.00726850396774359 ); GNF2_PCAF ( 0.00801799922829738 ); GNF2_PPP6C ( 0.00851741119309746 ); GNF2_UBE2I ( 0.00851741119309746 ); module_278 ( 0.00851741119309746 ); GNF2_RFC3 ( 0.00951563169487812 ); ----------------C5-------------- PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS ( 0.00226028338010609 ); RIBONUCLEOTIDE_METABOLIC_PROCESS ( 0.00351422918182454 ); NUCLEOTIDE_BIOSYNTHETIC_PROCESS ( 0.00451647780659392 ); RESPONSE_TO_DRUG ( 0.00526763491852544 ); NUCLEOTIDE_METABOLIC_PROCESS ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0031497 chromatin assembly ( 0.00647177810185883 ); GO:0034728 nucleosome organization ( 0.00805762385164503 ); GO:0009142 nucleoside triphosphate biosynthetic process ( 0.00647177810185883 ); GO:0009201 ribonucleoside triphosphate biosynthetic process ( 0.00805762385164503 ); GO:0006323 DNA packaging ( 0.00647177810185883 ); GO:0009199 ribonucleoside triphosphate metabolic process ( 0.00805762385164503 ); GO:0006333 chromatin assembly or disassembly ( 0.00647177810185883 ); GO:0009141 nucleoside triphosphate metabolic process ( 0.00805762385164503 ); GO:0009260 ribonucleotide biosynthetic process ( 0.00647177810185883 ); GO:0009259 ribonucleotide metabolic process ( 0.00805762385164503 ); GO:0003883 CTP synthase activity ( 0.00647177810185883 ); GO:0016584 nucleosome positioning ( 0.00805762385164503 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00647177810185883 ); GO:0009165 nucleotide biosynthetic process ( 0.00805762385164503 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00647177810185883 ); GO:0006753 nucleoside phosphate metabolic process ( 0.00805762385164503 ); GO:0009117 nucleotide metabolic process ( 0.00647177810185883 ); GO:0055086 nucleobase, nucleoside and nucleotide metabolic process ( 0.00805762385164503 ); GO:0006241 CTP biosynthetic process ( 0.00647177810185883 ); GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process ( 0.00805762385164503 ); GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process ( 0.00647177810185883 ); GO:0046036 CTP metabolic process ( 0.00805762385164503 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00647177810185883 ); GO:0005694 chromosome ( 0.00805762385164503 ); GO:0009147 pyrimidine nucleoside triphosphate metabolic process ( 0.00647177810185883 ); GO:0051276 chromosome organization ( 0.00805762385164503 ); GO:0009220 pyrimidine ribonucleotide biosynthetic process ( 0.00647177810185883 ); GO:0006541 glutamine metabolic process ( 0.00805762385164503 ); GO:0009218 pyrimidine ribonucleotide metabolic process ( 0.00647177810185883 ); GO:0005753 mitochondrial proton-transporting ATP synthase complex ( 0.00805762385164503 ); GO:0045259 proton-transporting ATP synthase complex ( 0.00647177810185883 ); GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain ( 0.00805762385164503 ); GO:0006221 pyrimidine nucleotide biosynthetic process ( 0.00647177810185883 ); GO:0006220 pyrimidine nucleotide metabolic process ( 0.00805762385164503 ); GO:0015985 energy coupled proton transport, down electrochemical gradient ( 0.00647177810185883 ); GO:0015986 ATP synthesis coupled proton transport ( 0.00805762385164503 ); GO:0034220 transmembrane ion transport ( 0.00647177810185883 ); GO:0022607 cellular component assembly ( 0.00805762385164503 ); ----------------GO-------------- GO:0031497 chromatin assembly ( 0.000124727401495844 ); GO:0034728 nucleosome organization ( 0.000139227004940191 ); GO:0009142 nucleoside triphosphate biosynthetic process ( 0.000228300235096572 ); GO:0009201 ribonucleoside triphosphate biosynthetic process ( 0.000228300235096572 ); GO:0006323 DNA packaging ( 0.000237914977669676 ); GO:0009199 ribonucleoside triphosphate metabolic process ( 0.00027833569522307 ); GO:0006333 chromatin assembly or disassembly ( 0.000299721420768389 ); GO:0009141 nucleoside triphosphate metabolic process ( 0.000310707705091987 ); GO:0009260 ribonucleotide biosynthetic process ( 0.000356606187461715 ); GO:0009259 ribonucleotide metabolic process ( 0.000431300765906228 ); GO:0003883 CTP synthase activity ( 0.000502638846362036 ); GO:0016584 nucleosome positioning ( 0.00100507555575524 ); GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00150731018915273 ); GO:0009165 nucleotide biosynthetic process ( 0.0015221326155936 ); GO:0006325 establishment or maintenance of chromatin architecture ( 0.00185243033818052 ); GO:0006753 nucleoside phosphate metabolic process ( 0.00248279408634471 ); GO:0009117 nucleotide metabolic process ( 0.00248279408634471 ); GO:0055086 nucleobase, nucleoside and nucleotide metabolic process ( 0.0027020218355814 ); GO:0006241 CTP biosynthetic process ( 0.00276201309019264 ); GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process ( 0.00276201309019264 ); GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process ( 0.00276201309019264 ); GO:0046036 CTP metabolic process ( 0.00276201309019264 ); GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) ( 0.00276201309019264 ); GO:0005694 chromosome ( 0.00294682691306444 ); GO:0009147 pyrimidine nucleoside triphosphate metabolic process ( 0.003012802242921 ); GO:0051276 chromosome organization ( 0.00313284396808884 ); GO:0009220 pyrimidine ribonucleotide biosynthetic process ( 0.00401545434941553 ); GO:0006541 glutamine metabolic process ( 0.00426599128800043 ); GO:0009218 pyrimidine ribonucleotide metabolic process ( 0.00426599128800043 ); GO:0005753 mitochondrial proton-transporting ATP synthase complex ( 0.00451647780659392 ); GO:0045259 proton-transporting ATP synthase complex ( 0.00476691391280593 ); GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain ( 0.00526763491852544 ); GO:0006221 pyrimidine nucleotide biosynthetic process ( 0.00551791983325034 ); GO:0006220 pyrimidine nucleotide metabolic process ( 0.00876704173562382 ); GO:0015985 energy coupled proton transport, down electrochemical gradient ( 0.00926615197891789 ); GO:0015986 ATP synthesis coupled proton transport ( 0.00926615197891789 ); GO:0034220 transmembrane ion transport ( 0.00951563169487812 ); GO:0022607 cellular component assembly ( 0.00957071521494295 ); ----------------KEGG-------------- hsa00240 Pyrimidine metabolism ( 0.0226663222395764 ); hsa00190 Oxidative phosphorylation ( 0.0283295828828541 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO2_CLIP-SEQ_(Kishore_2011) ( 0.0158011636375619 ); AGO2_PAR-CLIP_(Kishore_2011) ( 0.0175304669253401 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0203163960251742 ); TIA1_iCLIP_(Wang_2010) ( 0.027267874956596 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3236 ========================= ----------------C2-------------- REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.00276201309019264 ); REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.003012802242921 ); REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.00351422918182454 ); REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.00351422918182454 ); REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.00376486698322764 ); REACTOME_BOTULINUM_NEUROTOXICITY ( 0.00451647780659392 ); REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE ( 0.00701857156693042 ); ----------------C3-------------- ( ); ----------------C4-------------- module_381 ( 0.003012802242921 ); GCM_CSNK1D ( 0.00601833852446665 ); GNF2_GLTSCR2 ( 0.00776821779082648 ); GNF2_RAB3A ( 0.00851741119309746 ); GNF2_MAPT ( 0.00951563169487812 ); ----------------C5-------------- NEUROTRANSMITTER_SECRETION ( 0.00326354093759351 ); REGULATED_SECRETORY_PATHWAY ( 0.00376486698322764 ); PHOSPHOINOSITIDE_BINDING ( 0.00376486698322764 ); DETECTION_OF_CHEMICAL_STIMULUS ( 0.00451647780659392 ); PROTEIN_HOMOOLIGOMERIZATION ( 0.00551791983325034 ); REGULATION_OF_NEUROTRANSMITTER_LEVELS ( 0.00601833852446665 ); EXOCYTOSIS ( 0.006268472316171 ); GENERATION_OF_A_SIGNAL_INVOLVED_IN_CELL_CELL_SIGNALING ( 0.00726850396774359 ); ----------------GOSLIM-------------- GO:0017075 syntaxin-1 binding ( ); GO:0030672 synaptic vesicle membrane ( ); GO:0005513 detection of calcium ion ( ); GO:0030666 endocytic vesicle membrane ( ); GO:0050750 low-density lipoprotein receptor binding ( ); GO:0070325 lipoprotein receptor binding ( ); GO:0005545 phosphatidylinositol binding ( ); GO:0017157 regulation of exocytosis ( ); GO:0042734 presynaptic membrane ( ); GO:0019905 syntaxin binding ( ); GO:0048306 calcium-dependent protein binding ( ); GO:0000149 SNARE binding ( ); GO:0009593 detection of chemical stimulus ( ); GO:0030665 clathrin coated vesicle membrane ( ); GO:0030139 endocytic vesicle ( ); GO:0007269 neurotransmitter secretion ( ); GO:0051592 response to calcium ion ( ); GO:0022625 cytosolic large ribosomal subunit ( ); GO:0030662 coated vesicle membrane ( ); ----------------GO-------------- GO:0017075 syntaxin-1 binding ( 0.000251344694113254 ); GO:0030672 synaptic vesicle membrane ( 0.00200934280751552 ); GO:0005513 detection of calcium ion ( 0.00226028338010609 ); GO:0030666 endocytic vesicle membrane ( 0.00226028338010609 ); GO:0050750 low-density lipoprotein receptor binding ( 0.00276201309019264 ); GO:0070325 lipoprotein receptor binding ( 0.00276201309019264 ); GO:0005545 phosphatidylinositol binding ( 0.00326354093759351 ); GO:0017157 regulation of exocytosis ( 0.00351422918182454 ); GO:0042734 presynaptic membrane ( 0.00376486698322764 ); GO:0019905 syntaxin binding ( 0.00401545434941553 ); GO:0048306 calcium-dependent protein binding ( 0.00426599128800043 ); GO:0000149 SNARE binding ( 0.00526763491852544 ); GO:0009593 detection of chemical stimulus ( 0.006268472316171 ); GO:0030665 clathrin coated vesicle membrane ( 0.00676858882979892 ); GO:0030139 endocytic vesicle ( 0.00751838603984234 ); GO:0007269 neurotransmitter secretion ( 0.00776821779082648 ); GO:0051592 response to calcium ion ( 0.00776821779082648 ); GO:0022625 cytosolic large ribosomal subunit ( 0.00926615197891789 ); GO:0030662 coated vesicle membrane ( 0.00951563169487812 ); ----------------KEGG-------------- ( 0.0179680868067102 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3252 ========================= ----------------C2-------------- REACTOME_GAP_JUNCTION_ASSEMBLY ( 0.00476691391280593 ); REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC ( 0.00701857156693042 ); REACTOME_GAP_JUNCTION_TRAFFICKING ( 0.00701857156693042 ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00551791983325034 ); ----------------C5-------------- INTERCALATED_DISC ( 0.00226028338010609 ); ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CELL_POLARITY ( 0.00476691391280593 ); ----------------GOSLIM-------------- GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity ( ); GO:0035088 establishment or maintenance of apical/basal cell polarity ( ); GO:0016272 prefoldin complex ( ); GO:0005922 connexon complex ( ); GO:0005921 gap junction ( ); GO:0007163 establishment or maintenance of cell polarity ( ); ----------------GO-------------- GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity ( 0.00200934280751552 ); GO:0035088 establishment or maintenance of apical/basal cell polarity ( 0.00251117347179275 ); GO:0016272 prefoldin complex ( 0.00251117347179275 ); GO:0005922 connexon complex ( 0.00501729961424691 ); GO:0005921 gap junction ( 0.00651855574874693 ); GO:0007163 establishment or maintenance of cell polarity ( 0.00801799922829738 ); ----------------KEGG-------------- ( 0.0339665599703324 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3260 ========================= ----------------C2-------------- BIOCARTA_TH1TH2_PATHWAY ( 0.00451647780659392 ); BIOCARTA_NKCELLS_PATHWAY ( 0.00501729961424691 ); BIOCARTA_CYTOKINE_PATHWAY ( 0.00526763491852544 ); BIOCARTA_IL12_PATHWAY ( 0.00551791983325034 ); ----------------C3-------------- ( ); ----------------C4-------------- module_14 ( 0.00351422918182454 ); module_516 ( 0.00376486698322764 ); module_178 ( 0.00401545434941553 ); module_444 ( 0.00426599128800043 ); module_362 ( 0.00501729961424691 ); module_300 ( 0.00801799922829738 ); module_511 ( 0.00851741119309746 ); ----------------C5-------------- INTERLEUKIN_2_PRODUCTION ( 0.00276201309019264 ); INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS ( 0.003012802242921 ); POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION ( 0.00326354093759351 ); INTERFERON_GAMMA_PRODUCTION ( 0.00351422918182454 ); REGULATION_OF_T_CELL_PROLIFERATION ( 0.00401545434941553 ); CYTOKINESIS ( 0.00476691391280593 ); T_CELL_PROLIFERATION ( 0.00476691391280593 ); CELL_DIVISION ( 0.00526763491852544 ); POSITIVE_REGULATION_OF_T_CELL_ACTIVATION ( 0.00526763491852544 ); ADAPTIVE_IMMUNE_RESPONSE_GO_0002460 ( 0.00576815436602829 ); POSITIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION ( 0.00576815436602829 ); ADAPTIVE_IMMUNE_RESPONSE ( 0.00601833852446665 ); REGULATION_OF_T_CELL_ACTIVATION ( 0.00701857156693042 ); CHROMOSOME__PERICENTRIC_REGION ( 0.00776821779082648 ); CHROMOSOME_SEGREGATION ( 0.00776821779082648 ); REGULATION_OF_CELL_ADHESION ( 0.00851741119309746 ); REGULATION_OF_LYMPHOCYTE_ACTIVATION ( 0.00851741119309746 ); CHROMATIN ( 0.00876704173562382 ); SPINDLE ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0042231 interleukin-13 biosynthetic process ( ); GO:0005721 centromeric heterochromatin ( ); GO:0032616 interleukin-13 production ( ); GO:0032604 granulocyte macrophage colony-stimulating factor production ( ); GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process ( ); GO:0042104 positive regulation of activated T cell proliferation ( ); GO:0030431 sleep ( ); GO:0042033 chemokine biosynthetic process ( ); GO:0046006 regulation of activated T cell proliferation ( ); GO:0050755 chemokine metabolic process ( ); GO:0042092 T-helper 2 type immune response ( ); GO:0042088 T-helper 1 type immune response ( ); GO:0050798 activated T cell proliferation ( ); GO:0009409 response to cold ( ); GO:0032602 chemokine production ( ); GO:0042095 interferon-gamma biosynthetic process ( ); GO:0005149 interleukin-1 receptor binding ( ); GO:0042094 interleukin-2 biosynthetic process ( ); GO:0000792 heterochromatin ( ); GO:0044249 cellular biosynthetic process ( ); GO:0009058 biosynthetic process ( ); GO:0032609 interferon-gamma production ( ); GO:0032623 interleukin-2 production ( ); GO:0042102 positive regulation of T cell proliferation ( ); GO:0050671 positive regulation of lymphocyte proliferation ( ); GO:0032946 positive regulation of mononuclear cell proliferation ( ); GO:0000910 cytokinesis ( ); ----------------GO-------------- GO:0042231 interleukin-13 biosynthetic process ( 0.000502638846362036 ); GO:0005721 centromeric heterochromatin ( 0.000753882464368472 ); GO:0032616 interleukin-13 production ( 0.00100507555575524 ); GO:0032604 granulocyte macrophage colony-stimulating factor production ( 0.00125621812814281 ); GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process ( 0.00125621812814281 ); GO:0042104 positive regulation of activated T cell proliferation ( 0.00175835174640371 ); GO:0030431 sleep ( 0.00226028338010609 ); GO:0042033 chemokine biosynthetic process ( 0.00226028338010609 ); GO:0046006 regulation of activated T cell proliferation ( 0.00226028338010609 ); GO:0050755 chemokine metabolic process ( 0.00226028338010609 ); GO:0042092 T-helper 2 type immune response ( 0.00251117347179275 ); GO:0042088 T-helper 1 type immune response ( 0.00276201309019264 ); GO:0050798 activated T cell proliferation ( 0.003012802242921 ); GO:0009409 response to cold ( 0.00326354093759351 ); GO:0032602 chemokine production ( 0.00326354093759351 ); GO:0042095 interferon-gamma biosynthetic process ( 0.00326354093759351 ); GO:0005149 interleukin-1 receptor binding ( 0.00351422918182454 ); GO:0042094 interleukin-2 biosynthetic process ( 0.00426599128800043 ); GO:0000792 heterochromatin ( 0.00501729961424691 ); GO:0044249 cellular biosynthetic process ( 0.00529029329202514 ); GO:0009058 biosynthetic process ( 0.00571911851215346 ); GO:0032609 interferon-gamma production ( 0.00576815436602829 ); GO:0032623 interleukin-2 production ( 0.00576815436602829 ); GO:0042102 positive regulation of T cell proliferation ( 0.00751838603984234 ); GO:0050671 positive regulation of lymphocyte proliferation ( 0.00876704173562382 ); GO:0032946 positive regulation of mononuclear cell proliferation ( 0.00901662199503184 ); GO:0000910 cytokinesis ( 0.00926615197891789 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.0110114547894771 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3266 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00726850396774359 ); ----------------C4-------------- module_205 ( 0.00163289696094969 ); module_68 ( 0.00651855574874693 ); module_298 ( 0.00651855574874693 ); ----------------C5-------------- DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX ( 0.00351422918182454 ); POST_GOLGI_VESICLE_MEDIATED_TRANSPORT ( 0.00351422918182454 ); BASAL_LAMINA ( 0.00526763491852544 ); INTERMEDIATE_FILAMENT_CYTOSKELETON ( 0.00601833852446665 ); INTERMEDIATE_FILAMENT ( 0.00601833852446665 ); BASEMENT_MEMBRANE ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0043000 Golgi to plasma membrane CFTR protein transport ( ); GO:0016013 syntrophin complex ( ); GO:0043001 Golgi to plasma membrane protein transport ( ); GO:0006893 Golgi to plasma membrane transport ( ); GO:0034451 centriolar satellite ( ); GO:0033209 tumor necrosis factor-mediated signaling pathway ( ); GO:0016010 dystrophin-associated glycoprotein complex ( ); GO:0006892 post-Golgi vesicle-mediated transport ( ); GO:0030165 PDZ domain binding ( ); GO:0044450 microtubule organizing center part ( ); ----------------GO-------------- GO:0043000 Golgi to plasma membrane CFTR protein transport ( 0.000502638846362036 ); GO:0016013 syntrophin complex ( 0.000502638846362036 ); GO:0043001 Golgi to plasma membrane protein transport ( 0.000753882464368472 ); GO:0006893 Golgi to plasma membrane transport ( 0.00125621812814281 ); GO:0034451 centriolar satellite ( 0.00175835174640371 ); GO:0033209 tumor necrosis factor-mediated signaling pathway ( 0.00226028338010609 ); GO:0016010 dystrophin-associated glycoprotein complex ( 0.00376486698322764 ); GO:0006892 post-Golgi vesicle-mediated transport ( 0.00476691391280593 ); GO:0030165 PDZ domain binding ( 0.00676858882979892 ); GO:0044450 microtubule organizing center part ( 0.00801799922829738 ); ----------------KEGG-------------- hsa05130 Pathogenic Escherichia coli infection - EHEC ( 0.012754297075905 ); hsa05131 Pathogenic Escherichia coli infection - EPEC ( 0.012754297075905 ); hsa01430 Cell junctions ( 0.0339665599703324 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3269 ========================= ----------------C2-------------- REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND ( 0.00251117347179275 ); REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE ( 0.00351422918182454 ); REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR ( 0.00376486698322764 ); REACTOME_PHASE_1_FUNCTIONALIZATION ( 0.00376486698322764 ); REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE ( 0.00376486698322764 ); KEGG_PHENYLALANINE_METABOLISM ( 0.00426599128800043 ); REACTOME_DUAL_INCISION_REACTION_IN_GG_NER ( 0.00501729961424691 ); REACTOME_LAGGING_STRAND_SYNTHESIS ( 0.00501729961424691 ); REACTOME_DOUBLE_STRAND_BREAK_REPAIR ( 0.00526763491852544 ); KEGG_MISMATCH_REPAIR ( 0.00576815436602829 ); KEGG_HOMOLOGOUS_RECOMBINATION ( 0.00701857156693042 ); REACTOME_EXTENSION_OF_TELOMERES ( 0.00701857156693042 ); KEGG_HISTIDINE_METABOLISM ( 0.00726850396774359 ); REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX ( 0.00751838603984234 ); KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM ( 0.00776821779082648 ); REACTOME_DNA_STRAND_ELONGATION ( 0.00776821779082648 ); REACTOME_GLOBAL_GENOMIC_NER ( 0.00826773035985462 ); KEGG_DNA_REPLICATION ( 0.00901662199503184 ); REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS ( 0.00926615197891789 ); KEGG_TRYPTOPHAN_METABOLISM ( 0.00976506115050757 ); ----------------C3-------------- ( 0.00594855760620817 ); ----------------C4-------------- module_557 ( 0.00251117347179275 ); module_98 ( 0.0035031484707678 ); module_168 ( 0.00551791983325034 ); module_222 ( 0.00551791983325034 ); module_373 ( 0.00551791983325034 ); module_371 ( 0.006268472316171 ); module_11 ( 0.00637509705113927 ); module_100 ( 0.00642335165038737 ); module_137 ( 0.00644754340163415 ); module_66 ( 0.00659359534509824 ); module_281 ( 0.00701857156693042 ); ----------------C5-------------- INTRACELLULAR_ORGANELLE_PART ( 0.00173765167865079 ); ORGANELLE_PART ( 0.00175986394343839 ); NUCLEAR_REPLICATION_FORK ( 0.00251117347179275 ); REPLICATION_FORK ( 0.00451647780659392 ); INORGANIC_ANION_TRANSPORT ( 0.00451647780659392 ); ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CELL_POLARITY ( 0.00476691391280593 ); CHLORIDE_CHANNEL_ACTIVITY ( 0.00476691391280593 ); ANION_CHANNEL_ACTIVITY ( 0.00501729961424691 ); ANION_TRANSPORT ( 0.00776821779082648 ); SINGLE_STRANDED_DNA_BINDING ( 0.00826773035985462 ); NUCLEAR_CHROMOSOME_PART ( 0.00851741119309746 ); MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS ( 0.00851741119309746 ); NON_MEMBRANE_BOUND_ORGANELLE ( 0.00893960341576746 ); INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE ( 0.00893960341576746 ); ----------------GOSLIM-------------- GO:0005662 DNA replication factor A complex ( ); GO:0008131 amine oxidase activity ( ); GO:0030894 replisome ( ); GO:0043601 nuclear replisome ( ); GO:0043596 nuclear replication fork ( ); GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor ( ); GO:0005247 voltage-gated chloride channel activity ( ); GO:0006297 nucleotide-excision repair, DNA gap filling ( ); GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors ( ); GO:0000718 nucleotide-excision repair, DNA damage removal ( ); GO:0008308 voltage-gated anion channel activity ( ); GO:0005657 replication fork ( ); GO:0007163 establishment or maintenance of cell polarity ( ); ----------------GO-------------- GO:0005662 DNA replication factor A complex ( 0.00100507555575524 ); GO:0008131 amine oxidase activity ( 0.00125621812814281 ); GO:0030894 replisome ( 0.003012802242921 ); GO:0043601 nuclear replisome ( 0.003012802242921 ); GO:0043596 nuclear replication fork ( 0.00351422918182454 ); GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor ( 0.00351422918182454 ); GO:0005247 voltage-gated chloride channel activity ( 0.00401545434941553 ); GO:0006297 nucleotide-excision repair, DNA gap filling ( 0.00426599128800043 ); GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors ( 0.00451647780659392 ); GO:0000718 nucleotide-excision repair, DNA damage removal ( 0.00526763491852544 ); GO:0008308 voltage-gated anion channel activity ( 0.00526763491852544 ); GO:0005657 replication fork ( 0.00726850396774359 ); GO:0007163 establishment or maintenance of cell polarity ( 0.00801799922829738 ); ----------------KEGG-------------- hsa00360 Phenylalanine metabolism ( 0.00501729961424691 ); hsa03430 Mismatch repair ( 0.00576815436602829 ); hsa03440 Homologous recombination ( 0.00701857156693042 ); hsa00220 Urea cycle and metabolism of amino groups ( 0.00726850396774359 ); hsa00340 Histidine metabolism ( 0.00826773035985462 ); hsa03030 DNA replication ( 0.00901662199503184 ); hsa00260 Glycine, serine and threonine metabolism ( 0.0102637693111522 ); hsa03420 Nucleotide excision repair ( 0.0107622765215984 ); hsa00350 Tyrosine metabolism ( 0.0112605828425807 ); hsa00380 Tryptophan metabolism ( 0.0125054701520912 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0159844851342638 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0483070795264641 ); ============================ group3278 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00551791983325034 ); ----------------C4-------------- ( ); ----------------C5-------------- POTASSIUM_ION_TRANSPORT ( 8.30762578460609e-05 ); MONOVALENT_INORGANIC_CATION_TRANSPORT ( 0.000209660115498295 ); METAL_ION_TRANSPORT ( 0.000333266517050282 ); CATION_TRANSPORT ( 0.000520110771665432 ); ION_TRANSPORT ( 0.000826459617934934 ); INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY ( 0.003012802242921 ); POTASSIUM_CHANNEL_REGULATOR_ACTIVITY ( 0.00326354093759351 ); CHANNEL_REGULATOR_ACTIVITY ( 0.00551791983325034 ); AUXILIARY_TRANSPORT_PROTEIN_ACTIVITY ( 0.00601833852446665 ); VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY ( 0.00901662199503184 ); ----------------GOSLIM-------------- GO:0005244 voltage-gated ion channel activity ( ); GO:0022832 voltage-gated channel activity ( ); GO:0005261 cation channel activity ( ); GO:0046873 metal ion transmembrane transporter activity ( ); GO:0022836 gated channel activity ( ); GO:0015672 monovalent inorganic cation transport ( ); GO:0005216 ion channel activity ( ); GO:0022838 substrate specific channel activity ( ); GO:0015267 channel activity ( ); GO:0022803 passive transmembrane transporter activity ( ); GO:0030001 metal ion transport ( ); GO:0008324 cation transmembrane transporter activity ( ); GO:0006812 cation transport ( ); GO:0005249 voltage-gated potassium channel activity ( ); GO:0005267 potassium channel activity ( ); GO:0030955 potassium ion binding ( ); GO:0015075 ion transmembrane transporter activity ( ); GO:0006811 ion transport ( ); GO:0022843 voltage-gated cation channel activity ( ); GO:0022891 substrate-specific transmembrane transporter activity ( ); GO:0006813 potassium ion transport ( ); GO:0022857 transmembrane transporter activity ( ); GO:0022892 substrate-specific transporter activity ( ); GO:0015467 G-protein activated inward rectifier potassium channel activity ( ); GO:0031420 alkali metal ion binding ( ); GO:0005215 transporter activity ( ); GO:0001539 ciliary or flagellar motility ( ); GO:0005227 calcium activated cation channel activity ( ); GO:0030317 sperm motility ( ); GO:0005242 inward rectifier potassium channel activity ( ); GO:0015459 potassium channel regulator activity ( ); GO:0001669 acrosome ( ); GO:0019861 flagellum ( ); ----------------GO-------------- GO:0005244 voltage-gated ion channel activity ( 7.67993815483941e-06 ); GO:0022832 voltage-gated channel activity ( 7.67993815483941e-06 ); GO:0005261 cation channel activity ( 1.76810995569242e-05 ); GO:0046873 metal ion transmembrane transporter activity ( 3.06284109747853e-05 ); GO:0022836 gated channel activity ( 3.0942898916378e-05 ); GO:0015672 monovalent inorganic cation transport ( 3.69744977919868e-05 ); GO:0005216 ion channel activity ( 5.91264410816509e-05 ); GO:0022838 substrate specific channel activity ( 6.35904982699805e-05 ); GO:0015267 channel activity ( 6.82715516123141e-05 ); GO:0022803 passive transmembrane transporter activity ( 6.82715516123141e-05 ); GO:0030001 metal ion transport ( 0.000107527835131711 ); GO:0008324 cation transmembrane transporter activity ( 0.000158401409519245 ); GO:0006812 cation transport ( 0.000168815508790251 ); GO:0005249 voltage-gated potassium channel activity ( 0.000214246437124665 ); GO:0005267 potassium channel activity ( 0.000350698116814638 ); GO:0030955 potassium ion binding ( 0.000386877397298869 ); GO:0015075 ion transmembrane transporter activity ( 0.000409685484355873 ); GO:0006811 ion transport ( 0.000432570187589328 ); GO:0022843 voltage-gated cation channel activity ( 0.000444430459083394 ); GO:0022891 substrate-specific transmembrane transporter activity ( 0.000559560730907034 ); GO:0006813 potassium ion transport ( 0.000578828261086398 ); GO:0022857 transmembrane transporter activity ( 0.000736238807229538 ); GO:0022892 substrate-specific transporter activity ( 0.000933860535418259 ); GO:0015467 G-protein activated inward rectifier potassium channel activity ( 0.00100507555575524 ); GO:0031420 alkali metal ion binding ( 0.00124533520005983 ); GO:0005215 transporter activity ( 0.00165918768938662 ); GO:0001539 ciliary or flagellar motility ( 0.00376486698322764 ); GO:0005227 calcium activated cation channel activity ( 0.00376486698322764 ); GO:0030317 sperm motility ( 0.00426599128800043 ); GO:0005242 inward rectifier potassium channel activity ( 0.00451647780659392 ); GO:0015459 potassium channel regulator activity ( 0.00526763491852544 ); GO:0001669 acrosome ( 0.00826773035985462 ); GO:0019861 flagellum ( 0.00926615197891789 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3283 ========================= ----------------C2-------------- REACTOME_UNWINDING_OF_DNA ( 0.00276201309019264 ); REACTOME_GLUTATHIONE_CONJUGATION ( 0.00426599128800043 ); KEGG_SELENOAMINO_ACID_METABOLISM ( 0.00651855574874693 ); KEGG_HISTIDINE_METABOLISM ( 0.00726850396774359 ); REACTOME_DNA_STRAND_ELONGATION ( 0.00776821779082648 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00326354093759351 ); ANION_CATION_SYMPORTER_ACTIVITY ( 0.00401545434941553 ); INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00476691391280593 ); SYMPORTER_ACTIVITY ( 0.00776821779082648 ); ----------------GOSLIM-------------- GO:0005315 inorganic phosphate transmembrane transporter activity ( ); GO:0005436 sodium:phosphate symporter activity ( ); GO:0006817 phosphate transport ( ); GO:0015114 phosphate transmembrane transporter activity ( ); GO:0004364 glutathione transferase activity ( ); GO:0015296 anion:cation symporter activity ( ); ----------------GO-------------- GO:0005315 inorganic phosphate transmembrane transporter activity ( 0.000753882464368472 ); GO:0005436 sodium:phosphate symporter activity ( 0.00175835174640371 ); GO:0006817 phosphate transport ( 0.00200934280751552 ); GO:0015114 phosphate transmembrane transporter activity ( 0.00326354093759351 ); GO:0004364 glutathione transferase activity ( 0.00551791983325034 ); GO:0015296 anion:cation symporter activity ( 0.00651855574874693 ); ----------------KEGG-------------- hsa00440 Aminophosphonate metabolism ( 0.00276201309019264 ); hsa00450 Selenoamino acid metabolism ( 0.006268472316171 ); hsa00340 Histidine metabolism ( 0.00826773035985462 ); hsa00150 Androgen and estrogen metabolism ( 0.0100144403534012 ); hsa00350 Tyrosine metabolism ( 0.0112605828425807 ); hsa00380 Tryptophan metabolism ( 0.0125054701520912 ); hsa00480 Glutathione metabolism ( 0.0125054701520912 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.015488084236395 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0159844851342638 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3289 ========================= ----------------C2-------------- ( 0.00601833852446665 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- STEROID_DEHYDROGENASE_ACTIVITY__ACTING_ON_THE_CH_OH_GROUP_OF_DONORS__NAD_OR_NADP_AS_ACCEPTOR ( 0.00251117347179275 ); STEROID_DEHYDROGENASE_ACTIVITY ( 0.00276201309019264 ); CELLULAR_LIPID_CATABOLIC_PROCESS ( 0.00826773035985462 ); LIPID_CATABOLIC_PROCESS ( 0.00901662199503184 ); ----------------GOSLIM-------------- GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity ( ); GO:0004303 estradiol 17-beta-dehydrogenase activity ( ); GO:0006706 steroid catabolic process ( ); GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ( ); GO:0016229 steroid dehydrogenase activity ( ); ----------------GO-------------- GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity ( 0.000753882464368472 ); GO:0004303 estradiol 17-beta-dehydrogenase activity ( 0.00251117347179275 ); GO:0006706 steroid catabolic process ( 0.00401545434941553 ); GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ( 0.00601833852446665 ); GO:0016229 steroid dehydrogenase activity ( 0.00676858882979892 ); ----------------KEGG-------------- ( 0.00576815436602829 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3300 ========================= ----------------C2-------------- BIOCARTA_SKP2E2F_PATHWAY ( 0.00251117347179275 ); BIOCARTA_RB_PATHWAY ( 0.003012802242921 ); BIOCARTA_P27_PATHWAY ( 0.00326354093759351 ); BIOCARTA_P53_PATHWAY ( 0.00401545434941553 ); REACTOME_CRMPS_IN_SEMA3A_SIGNALING ( 0.00401545434941553 ); BIOCARTA_MCM_PATHWAY ( 0.00451647780659392 ); BIOCARTA_CELLCYCLE_PATHWAY ( 0.00551791983325034 ); BIOCARTA_RACCYCD_PATHWAY ( 0.00651855574874693 ); BIOCARTA_G1_PATHWAY ( 0.00676858882979892 ); REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX ( 0.00751838603984234 ); REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS ( 0.00926615197891789 ); ----------------C3-------------- CATTGTYY_V$SOX9_B1 ( 0.0018259047414111 ); TTTGCAC,MIR-19A,MIR-19B ( 0.00464912685081165 ); CACGTTT,MIR-302A ( 0.00601833852446665 ); ----------------C4-------------- module_303 ( 0.00676858882979892 ); module_521 ( 0.00851741119309746 ); module_455 ( 0.00876704173562382 ); ----------------C5-------------- SPERM_MOTILITY ( 0.00276201309019264 ); G2_M_TRANSITION_OF_MITOTIC_CELL_CYCLE ( 0.00326354093759351 ); G1_PHASE_OF_MITOTIC_CELL_CYCLE ( 0.00326354093759351 ); G1_PHASE ( 0.00376486698322764 ); REGULATION_OF_DNA_REPLICATION ( 0.00476691391280593 ); REGULATION_OF_MITOTIC_CELL_CYCLE ( 0.00526763491852544 ); AXON_GUIDANCE ( 0.00551791983325034 ); RHO_PROTEIN_SIGNAL_TRANSDUCTION ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0019153 protein-disulfide reductase (glutathione) activity ( 0.00320184443535966 ); GO:0035173 histone kinase activity ( 0.00399118596242216 ); GO:0007089 traversing start control point of mitotic cell cycle ( 0.00320184443535966 ); GO:0051301 cell division ( 0.00399118596242216 ); GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor ( 0.00320184443535966 ); GO:0000307 cyclin-dependent protein kinase holoenzyme complex ( 0.00399118596242216 ); GO:0007342 fusion of sperm to egg plasma membrane ( 0.00320184443535966 ); GO:0007340 acrosome reaction ( 0.00399118596242216 ); GO:0000080 G1 phase of mitotic cell cycle ( 0.00320184443535966 ); GO:0000086 G2/M transition of mitotic cell cycle ( 0.00399118596242216 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00320184443535966 ); GO:0042995 cell projection ( 0.00399118596242216 ); GO:0051318 G1 phase ( 0.00320184443535966 ); GO:0030159 receptor signaling complex scaffold activity ( 0.00399118596242216 ); GO:0017156 calcium ion-dependent exocytosis ( 0.00320184443535966 ); GO:0030317 sperm motility ( 0.00399118596242216 ); GO:0045026 plasma membrane fusion ( 0.00320184443535966 ); GO:0005737 cytoplasm ( 0.00399118596242216 ); GO:0032947 protein complex scaffold ( 0.00320184443535966 ); GO:0006928 cell motion ( 0.00399118596242216 ); GO:0051674 localization of cell ( 0.00320184443535966 ); GO:0042802 identical protein binding ( 0.00399118596242216 ); GO:0004693 cyclin-dependent protein kinase activity ( 0.00320184443535966 ); GO:0016667 oxidoreductase activity, acting on sulfur group of donors ( 0.00399118596242216 ); GO:0000910 cytokinesis ( 0.00320184443535966 ); GO:0019861 flagellum ( 0.00399118596242216 ); ----------------GO-------------- GO:0019153 protein-disulfide reductase (glutathione) activity ( 0.000251344694113254 ); GO:0035173 histone kinase activity ( 0.000251344694113254 ); GO:0007089 traversing start control point of mitotic cell cycle ( 0.00125621812814281 ); GO:0051301 cell division ( 0.00147412098739802 ); GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor ( 0.00175835174640371 ); GO:0000307 cyclin-dependent protein kinase holoenzyme complex ( 0.00200934280751552 ); GO:0007342 fusion of sperm to egg plasma membrane ( 0.00226028338010609 ); GO:0007340 acrosome reaction ( 0.003012802242921 ); GO:0000080 G1 phase of mitotic cell cycle ( 0.00351422918182454 ); GO:0000086 G2/M transition of mitotic cell cycle ( 0.00376486698322764 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00376486698322764 ); GO:0042995 cell projection ( 0.00400834844351054 ); GO:0051318 G1 phase ( 0.00401545434941553 ); GO:0030159 receptor signaling complex scaffold activity ( 0.00401545434941553 ); GO:0017156 calcium ion-dependent exocytosis ( 0.00426599128800043 ); GO:0030317 sperm motility ( 0.00426599128800043 ); GO:0045026 plasma membrane fusion ( 0.00426599128800043 ); GO:0005737 cytoplasm ( 0.00446038045317404 ); GO:0032947 protein complex scaffold ( 0.00451647780659392 ); GO:0006928 cell motion ( 0.00456655135588172 ); GO:0051674 localization of cell ( 0.00456655135588172 ); GO:0042802 identical protein binding ( 0.00505097685073922 ); GO:0004693 cyclin-dependent protein kinase activity ( 0.00726850396774359 ); GO:0016667 oxidoreductase activity, acting on sulfur group of donors ( 0.00901662199503184 ); GO:0000910 cytokinesis ( 0.00926615197891789 ); GO:0019861 flagellum ( 0.00926615197891789 ); ----------------KEGG-------------- hsa00480 Glutathione metabolism ( 0.0125054701520912 ); hsa04115 p53 signaling pathway ( 0.0167287110265827 ); hsa05222 Small cell lung cancer ( 0.0214316916710394 ); hsa05215 Prostate cancer ( 0.0219256935355265 ); hsa04110 Cell cycle ( 0.0278381701471998 ); hsa04360 Axon guidance ( 0.0320088476835487 ); ----------------CARTA-------------- salmonellapathway ( 0.00451647780659392 ); igf1pathway ( 0.00576815436602829 ); malpathway ( 0.00576815436602829 ); bcrpathway ( 0.006268472316171 ); hbxpathway ( 0.00676858882979892 ); longevitypathway ( 0.00676858882979892 ); tpopathway ( 0.00726850396774359 ); ngfpathway ( 0.00751838603984234 ); mtorpathway ( 0.0105130480313538 ); pdgfpathway ( 0.0112605828425807 ); tcrpathway ( 0.0112605828425807 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3319 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_211 ( 0.00276201309019264 ); module_562 ( 0.00526763491852544 ); module_371 ( 0.006268472316171 ); module_210 ( 0.00676858882979892 ); ----------------C5-------------- PROTEINACEOUS_EXTRACELLULAR_MATRIX ( 0.000233083062009959 ); EXTRACELLULAR_MATRIX ( 0.000242795967050123 ); EXTRACELLULAR_REGION_PART ( 0.00263847148126201 ); DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX ( 0.00351422918182454 ); EXTRACELLULAR_REGION ( 0.0044846820886856 ); BASAL_LAMINA ( 0.00526763491852544 ); BASEMENT_MEMBRANE ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0016013 syntrophin complex ( 0.00233169757645826 ); GO:0005578 proteinaceous extracellular matrix ( 0.00233169757645826 ); GO:0031012 extracellular matrix ( 0.00233169757645826 ); GO:0008191 metalloendopeptidase inhibitor activity ( 0.00233169757645826 ); GO:0016010 dystrophin-associated glycoprotein complex ( 0.00233169757645826 ); GO:0030574 collagen catabolic process ( 0.00233169757645826 ); GO:0044243 multicellular organismal catabolic process ( 0.00233169757645826 ); GO:0032963 collagen metabolic process ( 0.00233169757645826 ); GO:0044259 multicellular organismal macromolecule metabolic process ( 0.00233169757645826 ); ----------------GO-------------- GO:0016013 syntrophin complex ( 0.000502638846362036 ); GO:0005578 proteinaceous extracellular matrix ( 0.00205728661961332 ); GO:0031012 extracellular matrix ( 0.00225787169457238 ); GO:0008191 metalloendopeptidase inhibitor activity ( 0.00251117347179275 ); GO:0016010 dystrophin-associated glycoprotein complex ( 0.00376486698322764 ); GO:0030574 collagen catabolic process ( 0.00526763491852544 ); GO:0044243 multicellular organismal catabolic process ( 0.00651855574874693 ); GO:0032963 collagen metabolic process ( 0.00801799922829738 ); GO:0044259 multicellular organismal macromolecule metabolic process ( 0.00851741119309746 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.0105130480313538 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3322 ========================= ----------------C2-------------- REACTOME_MICRORNA_BIOGENESIS ( 0.00451647780659392 ); REACTOME_SMOOTH_MUSCLE_CONTRACTION ( 0.00576815436602829 ); REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE ( 0.00601833852446665 ); REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING ( 0.00726850396774359 ); REACTOME_SPHINGOLIPID_METABOLISM ( 0.00776821779082648 ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00701857156693042 ); ----------------C5-------------- ACTIN_FILAMENT_BASED_MOVEMENT ( 0.00251117347179275 ); NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS ( 0.00276201309019264 ); DEFENSE_RESPONSE_TO_VIRUS ( 0.003012802242921 ); REGULATION_OF_VIRAL_REPRODUCTION ( 0.003012802242921 ); NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS ( 0.00351422918182454 ); REGULATION_OF_IMMUNE_EFFECTOR_PROCESS ( 0.00376486698322764 ); MYOSIN_COMPLEX ( 0.00401545434941553 ); INTERACTION_WITH_HOST ( 0.00426599128800043 ); DOUBLE_STRANDED_RNA_BINDING ( 0.00426599128800043 ); REGULATION_OF_DEFENSE_RESPONSE ( 0.00501729961424691 ); VIRAL_GENOME_REPLICATION ( 0.00526763491852544 ); CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT ( 0.00651855574874693 ); MOTOR_ACTIVITY ( 0.00701857156693042 ); REGULATION_OF_GENE_EXPRESSION__EPIGENETIC ( 0.00751838603984234 ); NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS ( 0.00776821779082648 ); SKELETAL_MUSCLE_DEVELOPMENT ( 0.00776821779082648 ); VIRAL_INFECTIOUS_CYCLE ( 0.00801799922829738 ); STRUCTURAL_CONSTITUENT_OF_MUSCLE ( 0.00801799922829738 ); NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY ( 0.00876704173562382 ); VIRAL_REPRODUCTIVE_PROCESS ( 0.00901662199503184 ); IMMUNE_EFFECTOR_PROCESS ( 0.00926615197891789 ); STRIATED_MUSCLE_DEVELOPMENT ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0050291 sphingosine N-acyltransferase activity ( ); GO:0016461 unconventional myosin complex ( ); GO:0030898 actin-dependent ATPase activity ( ); GO:0045815 positive regulation of gene expression, epigenetic ( ); GO:0046513 ceramide biosynthetic process ( ); GO:0046520 sphingoid biosynthetic process ( ); GO:0030049 muscle filament sliding ( ); GO:0033275 actin-myosin filament sliding ( ); GO:0070252 actin-mediated cell contraction ( ); GO:0030148 sphingolipid biosynthetic process ( ); GO:0030048 actin filament-based movement ( ); GO:0006672 ceramide metabolic process ( ); GO:0003725 double-stranded RNA binding ( ); GO:0046519 sphingoid metabolic process ( ); ----------------GO-------------- GO:0050291 sphingosine N-acyltransferase activity ( 0.00100507555575524 ); GO:0016461 unconventional myosin complex ( 0.00150731018915273 ); GO:0030898 actin-dependent ATPase activity ( 0.00150731018915273 ); GO:0045815 positive regulation of gene expression, epigenetic ( 0.00175835174640371 ); GO:0046513 ceramide biosynthetic process ( 0.00200934280751552 ); GO:0046520 sphingoid biosynthetic process ( 0.00226028338010609 ); GO:0030049 muscle filament sliding ( 0.003012802242921 ); GO:0033275 actin-myosin filament sliding ( 0.003012802242921 ); GO:0070252 actin-mediated cell contraction ( 0.003012802242921 ); GO:0030148 sphingolipid biosynthetic process ( 0.00526763491852544 ); GO:0030048 actin filament-based movement ( 0.00551791983325034 ); GO:0006672 ceramide metabolic process ( 0.00776821779082648 ); GO:0003725 double-stranded RNA binding ( 0.00801799922829738 ); GO:0046519 sphingoid metabolic process ( 0.00851741119309746 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.00310714701365914 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3336 ========================= ----------------C2-------------- BIOCARTA_SRCRPTP_PATHWAY ( 0.00251117347179275 ); BIOCARTA_TRKA_PATHWAY ( 0.003012802242921 ); BIOCARTA_AGPCR_PATHWAY ( 0.00326354093759351 ); BIOCARTA_CBL_PATHWAY ( 0.00326354093759351 ); BIOCARTA_ARENRF2_PATHWAY ( 0.00326354093759351 ); BIOCARTA_CDMAC_PATHWAY ( 0.00401545434941553 ); REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS ( 0.00401545434941553 ); BIOCARTA_CCR5_PATHWAY ( 0.00426599128800043 ); BIOCARTA_CALCINEURIN_PATHWAY ( 0.00451647780659392 ); BIOCARTA_CARDIACEGF_PATHWAY ( 0.00451647780659392 ); BIOCARTA_MEF2D_PATHWAY ( 0.00476691391280593 ); BIOCARTA_SPPA_PATHWAY ( 0.00526763491852544 ); BIOCARTA_NOS1_PATHWAY ( 0.00526763491852544 ); BIOCARTA_CHEMICAL_PATHWAY ( 0.00551791983325034 ); BIOCARTA_CCR3_PATHWAY ( 0.00576815436602829 ); BIOCARTA_CXCR4_PATHWAY ( 0.00601833852446665 ); BIOCARTA_EIF4_PATHWAY ( 0.00601833852446665 ); BIOCARTA_TPO_PATHWAY ( 0.00601833852446665 ); BIOCARTA_GH_PATHWAY ( 0.00676858882979892 ); BIOCARTA_EDG1_PATHWAY ( 0.00676858882979892 ); BIOCARTA_CREB_PATHWAY ( 0.00676858882979892 ); BIOCARTA_PYK2_PATHWAY ( 0.00701857156693042 ); REACTOME_TOLL_LIKE_RECEPTOR_4_CASCADE ( 0.00701857156693042 ); BIOCARTA_VEGF_PATHWAY ( 0.00726850396774359 ); REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS ( 0.00751838603984234 ); BIOCARTA_EGF_PATHWAY ( 0.00776821779082648 ); BIOCARTA_MYOSIN_PATHWAY ( 0.00776821779082648 ); BIOCARTA_AT1R_PATHWAY ( 0.00801799922829738 ); BIOCARTA_PDGF_PATHWAY ( 0.00801799922829738 ); BIOCARTA_BCR_PATHWAY ( 0.00851741119309746 ); BIOCARTA_GPCR_PATHWAY ( 0.00851741119309746 ); BIOCARTA_PAR1_PATHWAY ( 0.00926615197891789 ); BIOCARTA_FCER1_PATHWAY ( 0.00951563169487812 ); ----------------C3-------------- ( ); ----------------C4-------------- module_89 ( 0.00351422918182454 ); module_203 ( 0.00401545434941553 ); module_90 ( 0.00426599128800043 ); module_300 ( 0.00801799922829738 ); ----------------C5-------------- ( 0.00776821779082648 ); ----------------GOSLIM-------------- GO:0042953 lipoprotein transport ( 0.00282271214210976 ); GO:0004697 protein kinase C activity ( 0.00805762385164503 ); GO:0005246 calcium channel regulator activity ( 0.00282271214210976 ); GO:0007339 binding of sperm to zona pellucida ( 0.00805762385164503 ); GO:0035036 sperm-egg recognition ( 0.00282271214210976 ); GO:0009988 cell-cell recognition ( 0.00805762385164503 ); GO:0030317 sperm motility ( 0.00282271214210976 ); ----------------GO-------------- GO:0042953 lipoprotein transport ( 0.00200934280751552 ); GO:0004697 protein kinase C activity ( 0.003012802242921 ); GO:0005246 calcium channel regulator activity ( 0.00326354093759351 ); GO:0007339 binding of sperm to zona pellucida ( 0.00351422918182454 ); GO:0035036 sperm-egg recognition ( 0.00351422918182454 ); GO:0009988 cell-cell recognition ( 0.00426599128800043 ); GO:0030317 sperm motility ( 0.00426599128800043 ); ----------------KEGG-------------- hsa05223 Non-small cell lung cancer ( 0.0135004769077131 ); hsa05110 Vibrio cholerae infection ( 0.0144946814407505 ); hsa05214 Glioma ( 0.0159844851342638 ); hsa04662 B cell receptor signaling pathway ( 0.0162326104847266 ); hsa04720 Long-term potentiation ( 0.0177203116860579 ); hsa04370 VEGF signaling pathway ( 0.0182158119248157 ); hsa04730 Long-term depression ( 0.0184634870479424 ); hsa04070 Phosphatidylinositol signaling system ( 0.0189586873395312 ); hsa04664 Fc epsilon RI signaling pathway ( 0.0189586873395312 ); hsa04012 ErbB signaling pathway ( 0.0214316916710394 ); hsa04540 Gap junction ( 0.0238997063361746 ); hsa04912 GnRH signaling pathway ( 0.0246391388803511 ); hsa04916 Melanogenesis ( 0.0253781232383343 ); hsa04670 Leukocyte transendothelial migration ( 0.0288207968771993 ); hsa04650 Natural killer cell mediated cytotoxicity ( 0.0324985730389302 ); hsa04530 Tight junction ( 0.0327433613768923 ); hsa04310 Wnt signaling pathway ( 0.0373849339107717 ); hsa04020 Calcium signaling pathway ( 0.0439501834482882 ); hsa04510 Focal adhesion ( 0.0487901968957494 ); ----------------CARTA-------------- ( 0.00326354093759351 ); ----------------RBP-------------- ( ); ----------------immu-------------- BCR_signalling_pathway ( 0.0184634870479424 ); Natural_killer_cell_cytotoxicity ( 0.0324985730389302 ); ----------------ARE-------------- ( ); ============================ group3339 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00652037629294354 ); ----------------C4-------------- ( 0.00401545434941553 ); ----------------C5-------------- COLLAGEN_BINDING ( 0.003012802242921 ); INTEGRIN_COMPLEX ( 0.00451647780659392 ); CELL_MATRIX_ADHESION ( 0.00926615197891789 ); CELL_SUBSTRATE_ADHESION ( 0.00951563169487812 ); LIGAND_GATED_CHANNEL_ACTIVITY ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0019002 GMP binding ( ); GO:0030553 cGMP binding ( ); GO:0030551 cyclic nucleotide binding ( ); GO:0005518 collagen binding ( ); GO:0008305 integrin complex ( ); ----------------GO-------------- GO:0019002 GMP binding ( 0.00226028338010609 ); GO:0030553 cGMP binding ( 0.00226028338010609 ); GO:0030551 cyclic nucleotide binding ( 0.00551791983325034 ); GO:0005518 collagen binding ( 0.00651855574874693 ); GO:0008305 integrin complex ( 0.00676858882979892 ); ----------------KEGG-------------- hsa04512 ECM-receptor interaction ( 0.0206903146304798 ); hsa04510 Focal adhesion ( 0.0487901968957494 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3343 ========================= ----------------C2-------------- ( 0.00726850396774359 ); ----------------C3-------------- ( ); ----------------C4-------------- module_42 ( 0.006268472316171 ); module_77 ( 0.00701857156693042 ); ----------------C5-------------- NADH_DEHYDROGENASE_COMPLEX ( 0.00351422918182454 ); MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I ( 0.00351422918182454 ); RESPIRATORY_CHAIN_COMPLEX_I ( 0.00351422918182454 ); MITOCHONDRIAL_RESPIRATORY_CHAIN ( 0.00576815436602829 ); PROTEIN_AMINO_ACID_LIPIDATION ( 0.00601833852446665 ); LIPOPROTEIN_BIOSYNTHETIC_PROCESS ( 0.00651855574874693 ); TRANSFERASE_ACTIVITY__TRANSFERRING_ALKYL_OR_ARYL__OTHER_THAN_METHYL__GROUPS ( 0.00751838603984234 ); LIPOPROTEIN_METABOLIC_PROCESS ( 0.00826773035985462 ); ----------------GOSLIM-------------- GO:0018347 protein amino acid farnesylation ( ); GO:0004660 protein farnesyltransferase activity ( ); GO:0018343 protein farnesylation ( ); GO:0004311 farnesyltranstransferase activity ( ); GO:0004965 GABA-B receptor activity ( ); GO:0018346 protein amino acid prenylation ( ); GO:0018342 protein prenylation ( ); GO:0008318 protein prenyltransferase activity ( ); GO:0004659 prenyltransferase activity ( ); GO:0016740 transferase activity ( ); GO:0048146 positive regulation of fibroblast proliferation ( ); GO:0015020 glucuronosyltransferase activity ( ); GO:0048144 fibroblast proliferation ( ); GO:0048145 regulation of fibroblast proliferation ( ); GO:0016917 GABA receptor activity ( ); GO:0008066 glutamate receptor activity ( ); GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( ); GO:0005747 mitochondrial respiratory chain complex I ( ); GO:0030964 NADH dehydrogenase complex ( ); GO:0045271 respiratory chain complex I ( ); GO:0003954 NADH dehydrogenase activity ( ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( ); GO:0050136 NADH dehydrogenase (quinone) activity ( ); ----------------GO-------------- GO:0018347 protein amino acid farnesylation ( 0.000502638846362036 ); GO:0004660 protein farnesyltransferase activity ( 0.000502638846362036 ); GO:0018343 protein farnesylation ( 0.000753882464368472 ); GO:0004311 farnesyltranstransferase activity ( 0.00100507555575524 ); GO:0004965 GABA-B receptor activity ( 0.00100507555575524 ); GO:0018346 protein amino acid prenylation ( 0.00150731018915273 ); GO:0018342 protein prenylation ( 0.00175835174640371 ); GO:0008318 protein prenyltransferase activity ( 0.00200934280751552 ); GO:0004659 prenyltransferase activity ( 0.00351422918182454 ); GO:0016740 transferase activity ( 0.00442563747999745 ); GO:0048146 positive regulation of fibroblast proliferation ( 0.00451647780659392 ); GO:0015020 glucuronosyltransferase activity ( 0.00476691391280593 ); GO:0048144 fibroblast proliferation ( 0.006268472316171 ); GO:0048145 regulation of fibroblast proliferation ( 0.006268472316171 ); GO:0016917 GABA receptor activity ( 0.00676858882979892 ); GO:0008066 glutamate receptor activity ( 0.00751838603984234 ); GO:0006120 mitochondrial electron transport, NADH to ubiquinone ( 0.00901662199503184 ); GO:0005747 mitochondrial respiratory chain complex I ( 0.00901662199503184 ); GO:0030964 NADH dehydrogenase complex ( 0.00901662199503184 ); GO:0045271 respiratory chain complex I ( 0.00901662199503184 ); GO:0003954 NADH dehydrogenase activity ( 0.00926615197891789 ); GO:0008137 NADH dehydrogenase (ubiquinone) activity ( 0.00926615197891789 ); GO:0050136 NADH dehydrogenase (quinone) activity ( 0.00926615197891789 ); ----------------KEGG-------------- hsa03020 RNA polymerase ( 0.006268472316171 ); hsa00240 Pyrimidine metabolism ( 0.0226663222395764 ); hsa05012 Parkinson's disease ( 0.0280839013614591 ); hsa00190 Oxidative phosphorylation ( 0.0283295828828541 ); hsa05322 Systemic lupus erythematosus ( 0.0312738878389577 ); hsa00230 Purine metabolism ( 0.0364092446831654 ); hsa05010 Alzheimer's disease ( 0.039333941311084 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3345 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0015904 tetracycline transport ( ); GO:0015307 drug:hydrogen antiporter activity ( ); GO:0015520 tetracycline:hydrogen antiporter activity ( ); GO:0008493 tetracycline transporter activity ( ); GO:0042895 antibiotic transporter activity ( ); GO:0046677 response to antibiotic ( ); GO:0015893 drug transport ( ); GO:0015238 drug transporter activity ( ); GO:0015299 solute:hydrogen antiporter activity ( ); GO:0015298 solute:cation antiporter activity ( ); GO:0015300 solute:solute antiporter activity ( ); ----------------GO-------------- GO:0015904 tetracycline transport ( 0.00125621812814281 ); GO:0015307 drug:hydrogen antiporter activity ( 0.00125621812814281 ); GO:0015520 tetracycline:hydrogen antiporter activity ( 0.00125621812814281 ); GO:0008493 tetracycline transporter activity ( 0.00150731018915273 ); GO:0042895 antibiotic transporter activity ( 0.00150731018915273 ); GO:0046677 response to antibiotic ( 0.00251117347179275 ); GO:0015893 drug transport ( 0.00276201309019264 ); GO:0015238 drug transporter activity ( 0.00376486698322764 ); GO:0015299 solute:hydrogen antiporter activity ( 0.00476691391280593 ); GO:0015298 solute:cation antiporter activity ( 0.006268472316171 ); GO:0015300 solute:solute antiporter activity ( 0.00751838603984234 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.00597188741869525 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3361 ========================= ----------------C2-------------- REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS ( 0.00251117347179275 ); REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B ( 0.00426599128800043 ); REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE ( 0.00426599128800043 ); REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX ( 0.00451647780659392 ); ----------------C3-------------- ( 0.00251117347179275 ); ----------------C4-------------- module_315 ( 0.00376486698322764 ); GNF2_BUB1 ( 0.006268472316171 ); GNF2_MKI67 ( 0.00651855574874693 ); GNF2_H2AFX ( 0.00701857156693042 ); module_382 ( 0.00701857156693042 ); module_451 ( 0.00726850396774359 ); GNF2_SMC2L1 ( 0.00751838603984234 ); GNF2_TTK ( 0.00851741119309746 ); GNF2_ESPL1 ( 0.00876704173562382 ); GNF2_RRM2 ( 0.00901662199503184 ); GNF2_CKS1B ( 0.00901662199503184 ); GNF2_CENPE ( 0.00926615197891789 ); ----------------C5-------------- RIBONUCLEOPROTEIN_BINDING ( 0.00226028338010609 ); NUCLEAR_SPECK ( 0.00251117347179275 ); MITOCHONDRIAL_MEMBRANE_ORGANIZATION_AND_BIOGENESIS ( 0.00276201309019264 ); FEMALE_GAMETE_GENERATION ( 0.00426599128800043 ); PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY ( 0.00601833852446665 ); NUCLEAR_BODY ( 0.00801799922829738 ); SPINDLE ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0005744 mitochondrial inner membrane presequence translocase complex ( ); GO:0043021 ribonucleoprotein binding ( ); GO:0007006 mitochondrial membrane organization ( ); ----------------GO-------------- GO:0005744 mitochondrial inner membrane presequence translocase complex ( 0.00276201309019264 ); GO:0043021 ribonucleoprotein binding ( 0.00476691391280593 ); GO:0007006 mitochondrial membrane organization ( 0.00601833852446665 ); ----------------KEGG-------------- hsa04110 Cell cycle ( 0.0278381701471998 ); hsa04120 Ubiquitin mediated proteolysis ( 0.0324985730389302 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- AGO2_PAR-CLIP_(Kishore_2011) ( 0.0175304669253401 ); ELAVL1-MNASE_PAR-CLIP_(Kishore_2011) ( 0.0203163960251742 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3388 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00901662199503184 ); ----------------C4-------------- ( ); ----------------C5-------------- GLYCEROPHOSPHOLIPID_BIOSYNTHETIC_PROCESS ( 0.00751838603984234 ); PHOSPHOLIPID_BIOSYNTHETIC_PROCESS ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0004105 choline-phosphate cytidylyltransferase activity ( ); GO:0006656 phosphatidylcholine biosynthetic process ( ); GO:0046470 phosphatidylcholine metabolic process ( ); GO:0000781 chromosome, telomeric region ( ); ----------------GO-------------- GO:0004105 choline-phosphate cytidylyltransferase activity ( 0.000502638846362036 ); GO:0006656 phosphatidylcholine biosynthetic process ( 0.00251117347179275 ); GO:0046470 phosphatidylcholine metabolic process ( 0.00376486698322764 ); GO:0000781 chromosome, telomeric region ( 0.00651855574874693 ); ----------------KEGG-------------- hsa00440 Aminophosphonate metabolism ( 0.00276201309019264 ); hsa00564 Glycerophospholipid metabolism ( 0.0162326104847266 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3472 ========================= ----------------C2-------------- REACTOME_POLYMERASE_SWITCHING ( 0.00351422918182454 ); REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS ( 0.00376486698322764 ); REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE ( 0.00376486698322764 ); REACTOME_LAGGING_STRAND_SYNTHESIS ( 0.00501729961424691 ); KEGG_MISMATCH_REPAIR ( 0.00576815436602829 ); REACTOME_EXTENSION_OF_TELOMERES ( 0.00701857156693042 ); REACTOME_DNA_STRAND_ELONGATION ( 0.00776821779082648 ); REACTOME_GLOBAL_GENOMIC_NER ( 0.00826773035985462 ); KEGG_DNA_REPLICATION ( 0.00901662199503184 ); BIOCARTA_ALK_PATHWAY ( 0.00926615197891789 ); ----------------C3-------------- CTCTATG,MIR-368 ( 0.00901662199503184 ); TCTGATC,MIR-383 ( 0.00951563169487812 ); ----------------C4-------------- GNF2_MATK ( 0.00551791983325034 ); GNF2_CD7 ( 0.00926615197891789 ); ----------------C5-------------- ( 0.00451647780659392 ); ----------------GOSLIM-------------- GO:0001785 prostaglandin J receptor activity ( ); GO:0004956 prostaglandin D receptor activity ( ); GO:0019012 virion ( ); GO:0019028 viral capsid ( ); GO:0019031 viral envelope ( ); GO:0044423 virion part ( ); GO:0003689 DNA clamp loader activity ( ); GO:0033170 DNA-protein loading ATPase activity ( ); GO:0032196 transposition ( ); GO:0005663 DNA replication factor C complex ( ); GO:0030238 male sex determination ( ); GO:0004955 prostaglandin receptor activity ( ); GO:0004953 icosanoid receptor activity ( ); GO:0004954 prostanoid receptor activity ( ); GO:0006278 RNA-dependent DNA replication ( ); GO:0007004 telomere maintenance via telomerase ( ); GO:0010833 telomere maintenance via telomere lengthening ( ); GO:0006297 nucleotide-excision repair, DNA gap filling ( ); GO:0007530 sex determination ( ); GO:0000723 telomere maintenance ( ); GO:0032200 telomere organization ( ); GO:0005657 replication fork ( ); ----------------GO-------------- GO:0001785 prostaglandin J receptor activity ( 0.000502638846362036 ); GO:0004956 prostaglandin D receptor activity ( 0.000502638846362036 ); GO:0019012 virion ( 0.000753882464368472 ); GO:0019028 viral capsid ( 0.000753882464368472 ); GO:0019031 viral envelope ( 0.000753882464368472 ); GO:0044423 virion part ( 0.000753882464368472 ); GO:0003689 DNA clamp loader activity ( 0.00125621812814281 ); GO:0033170 DNA-protein loading ATPase activity ( 0.00125621812814281 ); GO:0032196 transposition ( 0.00150731018915273 ); GO:0005663 DNA replication factor C complex ( 0.00150731018915273 ); GO:0030238 male sex determination ( 0.00226028338010609 ); GO:0004955 prostaglandin receptor activity ( 0.00226028338010609 ); GO:0004953 icosanoid receptor activity ( 0.00251117347179275 ); GO:0004954 prostanoid receptor activity ( 0.00251117347179275 ); GO:0006278 RNA-dependent DNA replication ( 0.00376486698322764 ); GO:0007004 telomere maintenance via telomerase ( 0.00376486698322764 ); GO:0010833 telomere maintenance via telomere lengthening ( 0.00376486698322764 ); GO:0006297 nucleotide-excision repair, DNA gap filling ( 0.00426599128800043 ); GO:0007530 sex determination ( 0.00601833852446665 ); GO:0000723 telomere maintenance ( 0.00676858882979892 ); GO:0032200 telomere organization ( 0.00676858882979892 ); GO:0005657 replication fork ( 0.00726850396774359 ); ----------------KEGG-------------- hsa03430 Mismatch repair ( 0.00576815436602829 ); hsa03030 DNA replication ( 0.00901662199503184 ); hsa03420 Nucleotide excision repair ( 0.0107622765215984 ); ----------------CARTA-------------- ( 0.0102637693111522 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3488 ========================= ----------------C2-------------- REACTOME_DEPOLARIZATION_OF_THE_PRESYNAPTIC_TERMINAL_TRIGGERS_THE_OPENING_OF_CALCIUM_CHANNELS ( 0.003012802242921 ); REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE ( 0.00726850396774359 ); ----------------C3-------------- ( ); ----------------C4-------------- module_390 ( 0.00200934280751552 ); module_543 ( 0.00401545434941553 ); module_5 ( 0.00418397777166498 ); module_404 ( 0.00651855574874693 ); ----------------C5-------------- REPRODUCTIVE_PROCESS ( 0.000609345502625574 ); REPRODUCTION ( 0.0016204028201338 ); REGULATION_OF_LIPID_METABOLIC_PROCESS ( 0.003012802242921 ); MALE_GONAD_DEVELOPMENT ( 0.003012802242921 ); EMBRYO_IMPLANTATION ( 0.00326354093759351 ); STEROID_BIOSYNTHETIC_PROCESS ( 0.00576815436602829 ); DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS ( 0.00651855574874693 ); ----------------GOSLIM-------------- GO:0032696 negative regulation of interleukin-13 production ( 0.0078569449420589 ); GO:0032714 negative regulation of interleukin-5 production ( 0.00998275305329829 ); GO:0007538 primary sex determination ( 0.0078569449420589 ); GO:0032634 interleukin-5 production ( 0.00998275305329829 ); GO:0032674 regulation of interleukin-5 production ( 0.0078569449420589 ); GO:0032713 negative regulation of interleukin-4 production ( 0.00998275305329829 ); GO:0001553 luteinization ( 0.0078569449420589 ); GO:0032656 regulation of interleukin-13 production ( 0.00998275305329829 ); GO:0019834 phospholipase A2 inhibitor activity ( 0.0078569449420589 ); GO:0032616 interleukin-13 production ( 0.00998275305329829 ); GO:0032689 negative regulation of interferon-gamma production ( 0.0078569449420589 ); GO:0030325 adrenal gland development ( 0.00998275305329829 ); GO:0032633 interleukin-4 production ( 0.0078569449420589 ); GO:0032673 regulation of interleukin-4 production ( 0.00998275305329829 ); GO:0051457 maintenance of protein location in nucleus ( 0.0078569449420589 ); GO:0043487 regulation of RNA stability ( 0.00998275305329829 ); GO:0043488 regulation of mRNA stability ( 0.0078569449420589 ); GO:0004859 phospholipase inhibitor activity ( 0.00998275305329829 ); GO:0050810 regulation of steroid biosynthetic process ( 0.0078569449420589 ); GO:0007566 embryo implantation ( 0.00998275305329829 ); GO:0055102 lipase inhibitor activity ( 0.0078569449420589 ); GO:0042130 negative regulation of T cell proliferation ( 0.00998275305329829 ); GO:0032945 negative regulation of mononuclear cell proliferation ( 0.0078569449420589 ); GO:0050672 negative regulation of lymphocyte proliferation ( 0.00998275305329829 ); GO:0019218 regulation of steroid metabolic process ( 0.0078569449420589 ); GO:0001818 negative regulation of cytokine production ( 0.00998275305329829 ); GO:0032649 regulation of interferon-gamma production ( 0.0078569449420589 ); GO:0046890 regulation of lipid biosynthetic process ( 0.00998275305329829 ); GO:0050868 negative regulation of T cell activation ( 0.0078569449420589 ); GO:0032609 interferon-gamma production ( 0.00998275305329829 ); GO:0007530 sex determination ( 0.0078569449420589 ); GO:0007368 determination of left/right symmetry ( 0.00998275305329829 ); GO:0009799 determination of symmetry ( 0.0078569449420589 ); GO:0009855 determination of bilateral symmetry ( 0.00998275305329829 ); GO:0006357 regulation of transcription from RNA polymerase II promoter ( 0.0078569449420589 ); GO:0022414 reproductive process ( 0.00998275305329829 ); GO:0000003 reproduction ( 0.0078569449420589 ); GO:0008584 male gonad development ( 0.00998275305329829 ); GO:0022602 ovulation cycle process ( 0.0078569449420589 ); GO:0042698 ovulation cycle ( 0.00998275305329829 ); GO:0051250 negative regulation of lymphocyte activation ( 0.0078569449420589 ); GO:0032507 maintenance of protein location in cell ( 0.00998275305329829 ); GO:0002695 negative regulation of leukocyte activation ( 0.0078569449420589 ); GO:0008585 female gonad development ( 0.00998275305329829 ); GO:0046545 development of primary female sexual characteristics ( 0.0078569449420589 ); GO:0046546 development of primary male sexual characteristics ( 0.00998275305329829 ); GO:0046660 female sex differentiation ( 0.0078569449420589 ); GO:0051651 maintenance of location in cell ( 0.00998275305329829 ); GO:0045185 maintenance of protein location ( 0.0078569449420589 ); GO:0050866 negative regulation of cell activation ( 0.00998275305329829 ); ----------------GO-------------- GO:0032696 negative regulation of interleukin-13 production ( 0.000251344694113254 ); GO:0032714 negative regulation of interleukin-5 production ( 0.000251344694113254 ); GO:0007538 primary sex determination ( 0.000502638846362036 ); GO:0032634 interleukin-5 production ( 0.000502638846362036 ); GO:0032674 regulation of interleukin-5 production ( 0.000502638846362036 ); GO:0032713 negative regulation of interleukin-4 production ( 0.000502638846362036 ); GO:0001553 luteinization ( 0.000753882464368472 ); GO:0032656 regulation of interleukin-13 production ( 0.000753882464368472 ); GO:0019834 phospholipase A2 inhibitor activity ( 0.000753882464368472 ); GO:0032616 interleukin-13 production ( 0.00100507555575524 ); GO:0032689 negative regulation of interferon-gamma production ( 0.00100507555575524 ); GO:0030325 adrenal gland development ( 0.00150731018915273 ); GO:0032633 interleukin-4 production ( 0.00150731018915273 ); GO:0032673 regulation of interleukin-4 production ( 0.00150731018915273 ); GO:0051457 maintenance of protein location in nucleus ( 0.00200934280751552 ); GO:0043487 regulation of RNA stability ( 0.00276201309019264 ); GO:0043488 regulation of mRNA stability ( 0.00276201309019264 ); GO:0004859 phospholipase inhibitor activity ( 0.00276201309019264 ); GO:0050810 regulation of steroid biosynthetic process ( 0.00326354093759351 ); GO:0007566 embryo implantation ( 0.00351422918182454 ); GO:0055102 lipase inhibitor activity ( 0.00351422918182454 ); GO:0042130 negative regulation of T cell proliferation ( 0.00401545434941553 ); GO:0032945 negative regulation of mononuclear cell proliferation ( 0.00476691391280593 ); GO:0050672 negative regulation of lymphocyte proliferation ( 0.00476691391280593 ); GO:0019218 regulation of steroid metabolic process ( 0.00526763491852544 ); GO:0001818 negative regulation of cytokine production ( 0.00551791983325034 ); GO:0032649 regulation of interferon-gamma production ( 0.00551791983325034 ); GO:0046890 regulation of lipid biosynthetic process ( 0.00551791983325034 ); GO:0050868 negative regulation of T cell activation ( 0.00551791983325034 ); GO:0032609 interferon-gamma production ( 0.00576815436602829 ); GO:0007530 sex determination ( 0.00601833852446665 ); GO:0007368 determination of left/right symmetry ( 0.00676858882979892 ); GO:0009799 determination of symmetry ( 0.00676858882979892 ); GO:0009855 determination of bilateral symmetry ( 0.00676858882979892 ); GO:0006357 regulation of transcription from RNA polymerase II promoter ( 0.00684044291675657 ); GO:0022414 reproductive process ( 0.00689032556907774 ); GO:0000003 reproduction ( 0.00699060311302967 ); GO:0008584 male gonad development ( 0.00701857156693042 ); GO:0022602 ovulation cycle process ( 0.00751838603984234 ); GO:0042698 ovulation cycle ( 0.00776821779082648 ); GO:0051250 negative regulation of lymphocyte activation ( 0.00776821779082648 ); GO:0032507 maintenance of protein location in cell ( 0.00801799922829738 ); GO:0002695 negative regulation of leukocyte activation ( 0.00851741119309746 ); GO:0008585 female gonad development ( 0.00851741119309746 ); GO:0046545 development of primary female sexual characteristics ( 0.00926615197891789 ); GO:0046546 development of primary male sexual characteristics ( 0.00926615197891789 ); GO:0046660 female sex differentiation ( 0.00926615197891789 ); GO:0051651 maintenance of location in cell ( 0.00926615197891789 ); GO:0045185 maintenance of protein location ( 0.00951563169487812 ); GO:0050866 negative regulation of cell activation ( 0.00951563169487812 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3513 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00226028338010609 ); ----------------GOSLIM-------------- GO:0010165 response to X-ray ( ); GO:0015299 solute:hydrogen antiporter activity ( ); GO:0015298 solute:cation antiporter activity ( ); GO:0010212 response to ionizing radiation ( ); GO:0015300 solute:solute antiporter activity ( ); ----------------GO-------------- GO:0010165 response to X-ray ( 0.003012802242921 ); GO:0015299 solute:hydrogen antiporter activity ( 0.00476691391280593 ); GO:0015298 solute:cation antiporter activity ( 0.006268472316171 ); GO:0010212 response to ionizing radiation ( 0.00676858882979892 ); GO:0015300 solute:solute antiporter activity ( 0.00751838603984234 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3520 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$EGR1_01 ( 0.000918584180353436 ); V$STAT_01 ( 0.000956769222150505 ); V$LYF1_01 ( 0.00102542497841582 ); YCATTAA_UNKNOWN ( 0.00430306311332555 ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0021568 rhombomere 2 development ( ); GO:0021593 rhombomere morphogenesis ( ); GO:0021658 rhombomere 3 morphogenesis ( ); GO:0021569 rhombomere 3 development ( ); GO:0035283 central nervous system segmentation ( ); GO:0035284 brain segmentation ( ); GO:0048703 embryonic viscerocranium morphogenesis ( ); GO:0021546 rhombomere development ( ); GO:0002076 osteoblast development ( ); GO:0007379 segment specification ( ); GO:0008045 motor axon guidance ( ); GO:0042474 middle ear morphogenesis ( ); GO:0048701 embryonic cranial skeleton morphogenesis ( ); GO:0045665 negative regulation of neuron differentiation ( ); GO:0006357 regulation of transcription from RNA polymerase II promoter ( ); GO:0001709 cell fate determination ( ); GO:0035282 segmentation ( ); GO:0009880 embryonic pattern specification ( ); GO:0009953 dorsal/ventral pattern formation ( ); GO:0030902 hindbrain development ( ); ----------------GO-------------- GO:0021568 rhombomere 2 development ( 0.000502638846362036 ); GO:0021593 rhombomere morphogenesis ( 0.000502638846362036 ); GO:0021658 rhombomere 3 morphogenesis ( 0.000502638846362036 ); GO:0021569 rhombomere 3 development ( 0.000753882464368472 ); GO:0035283 central nervous system segmentation ( 0.000753882464368472 ); GO:0035284 brain segmentation ( 0.000753882464368472 ); GO:0048703 embryonic viscerocranium morphogenesis ( 0.00100507555575524 ); GO:0021546 rhombomere development ( 0.00150731018915273 ); GO:0002076 osteoblast development ( 0.00200934280751552 ); GO:0007379 segment specification ( 0.00226028338010609 ); GO:0008045 motor axon guidance ( 0.00226028338010609 ); GO:0042474 middle ear morphogenesis ( 0.00226028338010609 ); GO:0048701 embryonic cranial skeleton morphogenesis ( 0.00251117347179275 ); GO:0045665 negative regulation of neuron differentiation ( 0.00601833852446665 ); GO:0006357 regulation of transcription from RNA polymerase II promoter ( 0.00684044291675657 ); GO:0001709 cell fate determination ( 0.00726850396774359 ); GO:0035282 segmentation ( 0.00801799922829738 ); GO:0009880 embryonic pattern specification ( 0.00826773035985462 ); GO:0009953 dorsal/ventral pattern formation ( 0.00851741119309746 ); GO:0030902 hindbrain development ( 0.00951563169487812 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3546 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3549 ========================= ----------------C2-------------- BIOCARTA_RNA_PATHWAY ( 0.00251117347179275 ); REACTOME_ACTIVATION_OF_CHAPERONES_BY_IRE1_ALPHA ( 0.00251117347179275 ); REACTOME_UNFOLDED_PROTEIN_RESPONSE ( 0.00476691391280593 ); ----------------C3-------------- ( ); ----------------C4-------------- module_439 ( 0.00501729961424691 ); module_522 ( 0.00801799922829738 ); GNF2_DENR ( 0.00976506115050757 ); ----------------C5-------------- CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY ( 0.00326354093759351 ); PROTEIN_COMPLEX_DISASSEMBLY ( 0.00351422918182454 ); MACROMOLECULAR_COMPLEX_DISASSEMBLY ( 0.00376486698322764 ); PROTEIN_KINASE_INHIBITOR_ACTIVITY ( 0.00601833852446665 ); KINASE_INHIBITOR_ACTIVITY ( 0.006268472316171 ); DOUBLE_STRANDED_DNA_BINDING ( 0.00801799922829738 ); CELLULAR_COMPONENT_DISASSEMBLY ( 0.00826773035985462 ); CYTOPLASM ( 0.00915776190761601 ); PROTEIN_KINASE_REGULATOR_ACTIVITY ( 0.00976506115050757 ); ----------------GOSLIM-------------- GO:0006393 termination of mitochondrial transcription ( ); GO:0030338 CMP-N-acetylneuraminate monooxygenase activity ( ); GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen ( ); GO:0003715 transcription termination factor activity ( ); GO:0006390 transcription from mitochondrial promoter ( ); GO:0006353 transcription termination ( ); GO:0005732 small nucleolar ribonucleoprotein complex ( ); GO:0051537 2 iron, 2 sulfur cluster binding ( ); GO:0031202 RNA splicing factor activity, transesterification mechanism ( ); GO:0004860 protein kinase inhibitor activity ( ); GO:0019210 kinase inhibitor activity ( ); ----------------GO-------------- GO:0006393 termination of mitochondrial transcription ( 0.000251344694113254 ); GO:0030338 CMP-N-acetylneuraminate monooxygenase activity ( 0.000251344694113254 ); GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen ( 0.000753882464368472 ); GO:0003715 transcription termination factor activity ( 0.00100507555575524 ); GO:0006390 transcription from mitochondrial promoter ( 0.00125621812814281 ); GO:0006353 transcription termination ( 0.00175835174640371 ); GO:0005732 small nucleolar ribonucleoprotein complex ( 0.00376486698322764 ); GO:0051537 2 iron, 2 sulfur cluster binding ( 0.00401545434941553 ); GO:0031202 RNA splicing factor activity, transesterification mechanism ( 0.00601833852446665 ); GO:0004860 protein kinase inhibitor activity ( 0.00851741119309746 ); GO:0019210 kinase inhibitor activity ( 0.00876704173562382 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.00376486698322764 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3560 ========================= ----------------C2-------------- REACTOME_COMMON_PATHWAY ( 0.00351422918182454 ); REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE ( 0.00801799922829738 ); ----------------C3-------------- ( ); ----------------C4-------------- module_557 ( 0.00251117347179275 ); module_470 ( 0.00351422918182454 ); module_368 ( 0.00451647780659392 ); module_162 ( 0.00476691391280593 ); module_218 ( 0.00501729961424691 ); GCM_ERCC4 ( 0.00701857156693042 ); GCM_TEC ( 0.00801799922829738 ); GCM_CDH5 ( 0.00876704173562382 ); ----------------C5-------------- NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION ( 0.00251117347179275 ); LEUKOCYTE_CHEMOTAXIS ( 0.00276201309019264 ); NEGATIVE_REGULATION_OF_ANGIOGENESIS ( 0.00326354093759351 ); LEUKOCYTE_MIGRATION ( 0.00326354093759351 ); PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00326354093759351 ); ANION_CATION_SYMPORTER_ACTIVITY ( 0.00401545434941553 ); REGULATION_OF_MYELOID_CELL_DIFFERENTIATION ( 0.00476691391280593 ); INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00476691391280593 ); SODIUM_ION_TRANSPORT ( 0.00526763491852544 ); CYTOKINE_AND_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY ( 0.00551791983325034 ); HEPARIN_BINDING ( 0.00576815436602829 ); REGULATION_OF_ANGIOGENESIS ( 0.006268472316171 ); NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION ( 0.00701857156693042 ); SYMPORTER_ACTIVITY ( 0.00776821779082648 ); GLYCOSAMINOGLYCAN_BINDING ( 0.00851741119309746 ); POLYSACCHARIDE_BINDING ( 0.00901662199503184 ); MYELOID_CELL_DIFFERENTIATION ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0045653 negative regulation of megakaryocyte differentiation ( ); GO:0045652 regulation of megakaryocyte differentiation ( ); GO:0045918 negative regulation of cytolysis ( ); GO:0045347 negative regulation of MHC class II biosynthetic process ( ); GO:0042268 regulation of cytolysis ( ); GO:0030219 megakaryocyte differentiation ( ); GO:0045342 MHC class II biosynthetic process ( ); GO:0045346 regulation of MHC class II biosynthetic process ( ); GO:0032760 positive regulation of tumor necrosis factor production ( ); GO:0005436 sodium:phosphate symporter activity ( ); GO:0031069 hair follicle morphogenesis ( ); GO:0010744 positive regulation of foam cell differentiation ( ); GO:0015114 phosphate transmembrane transporter activity ( ); GO:0045651 positive regulation of macrophage differentiation ( ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( ); GO:0016525 negative regulation of angiogenesis ( ); GO:0032680 regulation of tumor necrosis factor production ( ); GO:0010743 regulation of foam cell differentiation ( ); GO:0032640 tumor necrosis factor production ( ); GO:0019835 cytolysis ( ); GO:0015296 anion:cation symporter activity ( ); GO:0001942 hair follicle development ( ); GO:0010742 foam cell differentiation ( ); GO:0022404 molting cycle process ( ); GO:0022405 hair cycle process ( ); GO:0042303 molting cycle ( ); GO:0042633 hair cycle ( ); GO:0030168 platelet activation ( ); GO:0045638 negative regulation of myeloid cell differentiation ( ); GO:0045649 regulation of macrophage differentiation ( ); GO:0045639 positive regulation of myeloid cell differentiation ( ); GO:0030595 leukocyte chemotaxis ( ); GO:0060326 cell chemotaxis ( ); GO:0031093 platelet alpha granule lumen ( ); GO:0031983 vesicle lumen ( ); GO:0060205 cytoplasmic membrane-bounded vesicle lumen ( ); ----------------GO-------------- GO:0045653 negative regulation of megakaryocyte differentiation ( 0.000251344694113254 ); GO:0045652 regulation of megakaryocyte differentiation ( 0.000502638846362036 ); GO:0045918 negative regulation of cytolysis ( 0.000502638846362036 ); GO:0045347 negative regulation of MHC class II biosynthetic process ( 0.000753882464368472 ); GO:0042268 regulation of cytolysis ( 0.00100507555575524 ); GO:0030219 megakaryocyte differentiation ( 0.00125621812814281 ); GO:0045342 MHC class II biosynthetic process ( 0.00125621812814281 ); GO:0045346 regulation of MHC class II biosynthetic process ( 0.00125621812814281 ); GO:0032760 positive regulation of tumor necrosis factor production ( 0.00175835174640371 ); GO:0005436 sodium:phosphate symporter activity ( 0.00175835174640371 ); GO:0031069 hair follicle morphogenesis ( 0.00251117347179275 ); GO:0010744 positive regulation of foam cell differentiation ( 0.00326354093759351 ); GO:0015114 phosphate transmembrane transporter activity ( 0.00326354093759351 ); GO:0045651 positive regulation of macrophage differentiation ( 0.00426599128800043 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.00526763491852544 ); GO:0016525 negative regulation of angiogenesis ( 0.00526763491852544 ); GO:0032680 regulation of tumor necrosis factor production ( 0.00526763491852544 ); GO:0010743 regulation of foam cell differentiation ( 0.00551791983325034 ); GO:0032640 tumor necrosis factor production ( 0.00551791983325034 ); GO:0019835 cytolysis ( 0.00601833852446665 ); GO:0015296 anion:cation symporter activity ( 0.00651855574874693 ); GO:0001942 hair follicle development ( 0.00676858882979892 ); GO:0010742 foam cell differentiation ( 0.00676858882979892 ); GO:0022404 molting cycle process ( 0.00676858882979892 ); GO:0022405 hair cycle process ( 0.00676858882979892 ); GO:0042303 molting cycle ( 0.00701857156693042 ); GO:0042633 hair cycle ( 0.00701857156693042 ); GO:0030168 platelet activation ( 0.00726850396774359 ); GO:0045638 negative regulation of myeloid cell differentiation ( 0.00726850396774359 ); GO:0045649 regulation of macrophage differentiation ( 0.00751838603984234 ); GO:0045639 positive regulation of myeloid cell differentiation ( 0.00776821779082648 ); GO:0030595 leukocyte chemotaxis ( 0.00801799922829738 ); GO:0060326 cell chemotaxis ( 0.00801799922829738 ); GO:0031093 platelet alpha granule lumen ( 0.00826773035985462 ); GO:0031983 vesicle lumen ( 0.00876704173562382 ); GO:0060205 cytoplasmic membrane-bounded vesicle lumen ( 0.00876704173562382 ); ----------------KEGG-------------- ( 0.0339665599703324 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3578 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( 0.00451647780659392 ); ----------------C4-------------- ( ); ----------------C5-------------- POTASSIUM_CHANNEL_REGULATOR_ACTIVITY ( 0.00326354093759351 ); REGULATION_OF_IMMUNE_EFFECTOR_PROCESS ( 0.00376486698322764 ); CHROMATIN_REMODELING_COMPLEX ( 0.00426599128800043 ); REGULATION_OF_DEFENSE_RESPONSE ( 0.00501729961424691 ); CHANNEL_REGULATOR_ACTIVITY ( 0.00551791983325034 ); INNATE_IMMUNE_RESPONSE ( 0.00576815436602829 ); AUXILIARY_TRANSPORT_PROTEIN_ACTIVITY ( 0.00601833852446665 ); REGULATION_OF_IMMUNE_RESPONSE ( 0.00826773035985462 ); IMMUNE_EFFECTOR_PROCESS ( 0.00926615197891789 ); ----------------GOSLIM-------------- GO:0002715 regulation of natural killer cell mediated immunity ( ); GO:0042269 regulation of natural killer cell mediated cytotoxicity ( ); GO:0015269 calcium-activated potassium channel activity ( ); GO:0022839 ion gated channel activity ( ); GO:0001910 regulation of leukocyte mediated cytotoxicity ( ); GO:0005227 calcium activated cation channel activity ( ); GO:0002228 natural killer cell mediated immunity ( ); GO:0031341 regulation of cell killing ( ); GO:0042267 natural killer cell mediated cytotoxicity ( ); GO:0001909 leukocyte mediated cytotoxicity ( ); GO:0030101 natural killer cell activation ( ); GO:0015459 potassium channel regulator activity ( ); GO:0001906 cell killing ( ); GO:0045088 regulation of innate immune response ( ); GO:0002706 regulation of lymphocyte mediated immunity ( ); ----------------GO-------------- GO:0002715 regulation of natural killer cell mediated immunity ( 0.003012802242921 ); GO:0042269 regulation of natural killer cell mediated cytotoxicity ( 0.003012802242921 ); GO:0015269 calcium-activated potassium channel activity ( 0.003012802242921 ); GO:0022839 ion gated channel activity ( 0.00326354093759351 ); GO:0001910 regulation of leukocyte mediated cytotoxicity ( 0.00351422918182454 ); GO:0005227 calcium activated cation channel activity ( 0.00376486698322764 ); GO:0002228 natural killer cell mediated immunity ( 0.00426599128800043 ); GO:0031341 regulation of cell killing ( 0.00426599128800043 ); GO:0042267 natural killer cell mediated cytotoxicity ( 0.00426599128800043 ); GO:0001909 leukocyte mediated cytotoxicity ( 0.00476691391280593 ); GO:0030101 natural killer cell activation ( 0.00501729961424691 ); GO:0015459 potassium channel regulator activity ( 0.00526763491852544 ); GO:0001906 cell killing ( 0.006268472316171 ); GO:0045088 regulation of innate immune response ( 0.00651855574874693 ); GO:0002706 regulation of lymphocyte mediated immunity ( 0.00926615197891789 ); ----------------KEGG-------------- ( 0.0324985730389302 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0324985730389302 ); ----------------ARE-------------- ( ); ============================ group3579 ========================= ----------------C2-------------- ( ); ----------------C3-------------- V$ARNT_02 ( 0.000782189093307707 ); V$CP2_02 ( 0.000782189093307707 ); V$ROAZ_01 ( 0.00251117347179275 ); ----------------C4-------------- ( 0.00351422918182454 ); ----------------C5-------------- NEUROTRANSMITTER_SECRETION ( 0.00326354093759351 ); REGULATED_SECRETORY_PATHWAY ( 0.00376486698322764 ); REGULATION_OF_NEUROTRANSMITTER_LEVELS ( 0.00601833852446665 ); GENERATION_OF_A_SIGNAL_INVOLVED_IN_CELL_CELL_SIGNALING ( 0.00726850396774359 ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( 0.00776821779082648 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3590 ========================= ----------------C2-------------- KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE ( 0.00551791983325034 ); KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE ( 0.00651855574874693 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00326354093759351 ); ANION_CATION_SYMPORTER_ACTIVITY ( 0.00401545434941553 ); INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ( 0.00476691391280593 ); SODIUM_ION_TRANSPORT ( 0.00526763491852544 ); SYMPORTER_ACTIVITY ( 0.00776821779082648 ); ----------------GOSLIM-------------- GO:0004305 ethanolamine kinase activity ( ); GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ( ); GO:0005436 sodium:phosphate symporter activity ( ); GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity ( ); GO:0048531 beta-1,3-galactosyltransferase activity ( ); GO:0015114 phosphate transmembrane transporter activity ( ); GO:0035250 UDP-galactosyltransferase activity ( ); GO:0015020 glucuronosyltransferase activity ( ); GO:0015296 anion:cation symporter activity ( ); GO:0008378 galactosyltransferase activity ( ); ----------------GO-------------- GO:0004305 ethanolamine kinase activity ( 0.000502638846362036 ); GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ( 0.000502638846362036 ); GO:0005436 sodium:phosphate symporter activity ( 0.00175835174640371 ); GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity ( 0.00175835174640371 ); GO:0048531 beta-1,3-galactosyltransferase activity ( 0.00200934280751552 ); GO:0015114 phosphate transmembrane transporter activity ( 0.00326354093759351 ); GO:0035250 UDP-galactosyltransferase activity ( 0.00401545434941553 ); GO:0015020 glucuronosyltransferase activity ( 0.00476691391280593 ); GO:0015296 anion:cation symporter activity ( 0.00651855574874693 ); GO:0008378 galactosyltransferase activity ( 0.00726850396774359 ); ----------------KEGG-------------- hsa00532 Chondroitin sulfate biosynthesis ( 0.00501729961424691 ); hsa00564 Glycerophospholipid metabolism ( 0.0162326104847266 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0293118121905235 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0483070795264641 ); ============================ group3631 ========================= ----------------C2-------------- REACTOME_PYRIMIDINE_CATABOLISM ( 0.00251117347179275 ); REACTOME_CLASS_C3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS ( 0.00376486698322764 ); REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT ( 0.00426599128800043 ); REACTOME_PYRIMIDINE_METABOLISM ( 0.00551791983325034 ); REACTOME_LIPOPROTEIN_METABOLISM ( 0.00676858882979892 ); REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN ( 0.00701857156693042 ); REACTOME_GLUCOSE_TRANSPORT ( 0.00926615197891789 ); ----------------C3-------------- ( ); ----------------C4-------------- module_236 ( 0.00426599128800043 ); GNF2_CDH3 ( 0.00601833852446665 ); GNF2_SERPINB5 ( 0.006268472316171 ); module_385 ( 0.00676858882979892 ); module_23 ( 0.00719320401577162 ); GCM_RAP2A ( 0.00751838603984234 ); GNF2_RAB3A ( 0.00851741119309746 ); module_96 ( 0.00876704173562382 ); module_410 ( 0.00876704173562382 ); GNF2_MAPT ( 0.00951563169487812 ); ----------------C5-------------- METABOTROPIC_GLUTAMATE__GABA_B_LIKE_RECEPTOR_ACTIVITY ( 0.00251117347179275 ); GABA_RECEPTOR_ACTIVITY ( 0.00276201309019264 ); TRANSFERASE_ACTIVITY__TRANSFERRING_PENTOSYL_GROUPS ( 0.00476691391280593 ); GLUTAMATE_RECEPTOR_ACTIVITY ( 0.00501729961424691 ); ----------------GOSLIM-------------- GO:0034359 mature chylomicron ( 0.000488122669767638 ); GO:0034360 chylomicron remnant ( 0.000488122669767638 ); GO:0006642 triglyceride mobilization ( 0.000488122669767638 ); GO:0046108 uridine metabolic process ( 0.000488122669767638 ); GO:0031904 endosome lumen ( 0.000488122669767638 ); GO:0004850 uridine phosphorylase activity ( 0.000488122669767638 ); GO:0046131 pyrimidine ribonucleoside metabolic process ( 0.000488122669767638 ); GO:0034383 low-density lipoprotein particle clearance ( 0.000488122669767638 ); GO:0034363 intermediate-density lipoprotein particle ( 0.000488122669767638 ); GO:0004965 GABA-B receptor activity ( 0.000488122669767638 ); GO:0001678 cellular glucose homeostasis ( 0.000488122669767638 ); GO:0034379 very-low-density lipoprotein particle assembly ( 0.000488122669767638 ); GO:0042159 lipoprotein catabolic process ( 0.000488122669767638 ); GO:0034362 low-density lipoprotein particle ( 0.000488122669767638 ); GO:0034374 low-density lipoprotein particle remodeling ( 0.000488122669767638 ); GO:0045540 regulation of cholesterol biosynthetic process ( 0.000488122669767638 ); GO:0030669 clathrin-coated endocytic vesicle membrane ( 0.000488122669767638 ); GO:0019433 triglyceride catabolic process ( 0.000488122669767638 ); GO:0034377 plasma lipoprotein particle assembly ( 0.000488122669767638 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.000488122669767638 ); GO:0042953 lipoprotein transport ( 0.000488122669767638 ); GO:0044269 glycerol ether catabolic process ( 0.000488122669767638 ); GO:0046461 neutral lipid catabolic process ( 0.000488122669767638 ); GO:0046464 acylglycerol catabolic process ( 0.000488122669767638 ); GO:0046503 glycerolipid catabolic process ( 0.000488122669767638 ); GO:0065005 protein-lipid complex assembly ( 0.000488122669767638 ); GO:0048844 artery morphogenesis ( 0.000488122669767638 ); GO:0030666 endocytic vesicle membrane ( 0.000488122669767638 ); GO:0045334 clathrin-coated endocytic vesicle ( 0.000488122669767638 ); GO:0006753 nucleoside phosphate metabolic process ( 0.000488122669767638 ); GO:0009117 nucleotide metabolic process ( 0.000488122669767638 ); GO:0034361 very-low-density lipoprotein particle ( 0.000488122669767638 ); GO:0034385 triglyceride-rich lipoprotein particle ( 0.000488122669767638 ); GO:0017127 cholesterol transporter activity ( 0.000488122669767638 ); GO:0055086 nucleobase, nucleoside and nucleotide metabolic process ( 0.000488122669767638 ); GO:0034367 macromolecular complex remodeling ( 0.000488122669767638 ); GO:0034368 protein-lipid complex remodeling ( 0.000488122669767638 ); GO:0034369 plasma lipoprotein particle remodeling ( 0.000488122669767638 ); GO:0034381 lipoprotein particle clearance ( 0.000488122669767638 ); GO:0050750 low-density lipoprotein receptor binding ( 0.000488122669767638 ); GO:0070325 lipoprotein receptor binding ( 0.000488122669767638 ); GO:0042627 chylomicron ( 0.000488122669767638 ); GO:0015248 sterol transporter activity ( 0.000488122669767638 ); GO:0048878 chemical homeostasis ( 0.000488122669767638 ); GO:0009119 ribonucleoside metabolic process ( 0.000488122669767638 ); GO:0010744 positive regulation of foam cell differentiation ( 0.000488122669767638 ); GO:0050810 regulation of steroid biosynthetic process ( 0.000488122669767638 ); GO:0007214 gamma-aminobutyric acid signaling pathway ( 0.000488122669767638 ); GO:0030317 sperm motility ( 0.000488122669767638 ); GO:0045651 positive regulation of macrophage differentiation ( 0.000488122669767638 ); GO:0005737 cytoplasm ( 0.000488122669767638 ); GO:0032994 protein-lipid complex ( 0.000488122669767638 ); GO:0034358 plasma lipoprotein particle ( 0.000488122669767638 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.000488122669767638 ); GO:0019218 regulation of steroid metabolic process ( 0.000488122669767638 ); GO:0045834 positive regulation of lipid metabolic process ( 0.000488122669767638 ); GO:0010743 regulation of foam cell differentiation ( 0.000488122669767638 ); GO:0046890 regulation of lipid biosynthetic process ( 0.000488122669767638 ); GO:0010742 foam cell differentiation ( 0.000488122669767638 ); GO:0030665 clathrin coated vesicle membrane ( 0.000488122669767638 ); GO:0016917 GABA receptor activity ( 0.000488122669767638 ); GO:0042632 cholesterol homeostasis ( 0.000488122669767638 ); GO:0055092 sterol homeostasis ( 0.000488122669767638 ); GO:0006695 cholesterol biosynthetic process ( 0.000488122669767638 ); GO:0009791 post-embryonic development ( 0.000488122669767638 ); GO:0045649 regulation of macrophage differentiation ( 0.000488122669767638 ); GO:0030139 endocytic vesicle ( 0.000488122669767638 ); GO:0008066 glutamate receptor activity ( 0.000488122669767638 ); GO:0000060 protein import into nucleus, translocation ( 0.000488122669767638 ); GO:0009116 nucleoside metabolic process ( 0.000488122669767638 ); GO:0045639 positive regulation of myeloid cell differentiation ( 0.000488122669767638 ); GO:0006641 triglyceride metabolic process ( 0.000488122669767638 ); GO:0007194 negative regulation of adenylate cyclase activity ( 0.000488122669767638 ); GO:0031280 negative regulation of cyclase activity ( 0.000488122669767638 ); GO:0033500 carbohydrate homeostasis ( 0.000488122669767638 ); GO:0042593 glucose homeostasis ( 0.000488122669767638 ); GO:0051350 negative regulation of lyase activity ( 0.000488122669767638 ); GO:0009166 nucleotide catabolic process ( 0.000488122669767638 ); GO:0042592 homeostatic process ( 0.000488122669767638 ); GO:0030301 cholesterol transport ( 0.000488122669767638 ); GO:0006220 pyrimidine nucleotide metabolic process ( 0.000488122669767638 ); GO:0015918 sterol transport ( 0.000488122669767638 ); GO:0055088 lipid homeostasis ( 0.000488122669767638 ); GO:0006638 neutral lipid metabolic process ( 0.000488122669767638 ); GO:0006639 acylglycerol metabolic process ( 0.000488122669767638 ); GO:0046486 glycerolipid metabolic process ( 0.000488122669767638 ); GO:0030662 coated vesicle membrane ( 0.000488122669767638 ); GO:0006662 glycerol ether metabolic process ( 0.000488122669767638 ); GO:0016126 sterol biosynthetic process ( 0.000488122669767638 ); ----------------GO-------------- GO:0034359 mature chylomicron ( 0.000251344694113254 ); GO:0034360 chylomicron remnant ( 0.000251344694113254 ); GO:0006642 triglyceride mobilization ( 0.000502638846362036 ); GO:0046108 uridine metabolic process ( 0.000502638846362036 ); GO:0031904 endosome lumen ( 0.000502638846362036 ); GO:0004850 uridine phosphorylase activity ( 0.000502638846362036 ); GO:0046131 pyrimidine ribonucleoside metabolic process ( 0.000753882464368472 ); GO:0034383 low-density lipoprotein particle clearance ( 0.00100507555575524 ); GO:0034363 intermediate-density lipoprotein particle ( 0.00100507555575524 ); GO:0004965 GABA-B receptor activity ( 0.00100507555575524 ); GO:0001678 cellular glucose homeostasis ( 0.00125621812814281 ); GO:0034379 very-low-density lipoprotein particle assembly ( 0.00125621812814281 ); GO:0042159 lipoprotein catabolic process ( 0.00125621812814281 ); GO:0034362 low-density lipoprotein particle ( 0.00125621812814281 ); GO:0034374 low-density lipoprotein particle remodeling ( 0.00150731018915273 ); GO:0045540 regulation of cholesterol biosynthetic process ( 0.00150731018915273 ); GO:0030669 clathrin-coated endocytic vesicle membrane ( 0.00150731018915273 ); GO:0019433 triglyceride catabolic process ( 0.00175835174640371 ); GO:0034377 plasma lipoprotein particle assembly ( 0.00175835174640371 ); GO:0006213 pyrimidine nucleoside metabolic process ( 0.00200934280751552 ); GO:0042953 lipoprotein transport ( 0.00200934280751552 ); GO:0044269 glycerol ether catabolic process ( 0.00200934280751552 ); GO:0046461 neutral lipid catabolic process ( 0.00200934280751552 ); GO:0046464 acylglycerol catabolic process ( 0.00200934280751552 ); GO:0046503 glycerolipid catabolic process ( 0.00200934280751552 ); GO:0065005 protein-lipid complex assembly ( 0.00200934280751552 ); GO:0048844 artery morphogenesis ( 0.00226028338010609 ); GO:0030666 endocytic vesicle membrane ( 0.00226028338010609 ); GO:0045334 clathrin-coated endocytic vesicle ( 0.00226028338010609 ); GO:0006753 nucleoside phosphate metabolic process ( 0.00248279408634471 ); GO:0009117 nucleotide metabolic process ( 0.00248279408634471 ); GO:0034361 very-low-density lipoprotein particle ( 0.00251117347179275 ); GO:0034385 triglyceride-rich lipoprotein particle ( 0.00251117347179275 ); GO:0017127 cholesterol transporter activity ( 0.00251117347179275 ); GO:0055086 nucleobase, nucleoside and nucleotide metabolic process ( 0.0027020218355814 ); GO:0034367 macromolecular complex remodeling ( 0.00276201309019264 ); GO:0034368 protein-lipid complex remodeling ( 0.00276201309019264 ); GO:0034369 plasma lipoprotein particle remodeling ( 0.00276201309019264 ); GO:0034381 lipoprotein particle clearance ( 0.00276201309019264 ); GO:0050750 low-density lipoprotein receptor binding ( 0.00276201309019264 ); GO:0070325 lipoprotein receptor binding ( 0.00276201309019264 ); GO:0042627 chylomicron ( 0.003012802242921 ); GO:0015248 sterol transporter activity ( 0.003012802242921 ); GO:0048878 chemical homeostasis ( 0.00309861505492276 ); GO:0009119 ribonucleoside metabolic process ( 0.00326354093759351 ); GO:0010744 positive regulation of foam cell differentiation ( 0.00326354093759351 ); GO:0050810 regulation of steroid biosynthetic process ( 0.00326354093759351 ); GO:0007214 gamma-aminobutyric acid signaling pathway ( 0.00401545434941553 ); GO:0030317 sperm motility ( 0.00426599128800043 ); GO:0045651 positive regulation of macrophage differentiation ( 0.00426599128800043 ); GO:0005737 cytoplasm ( 0.00446038045317404 ); GO:0032994 protein-lipid complex ( 0.00451647780659392 ); GO:0034358 plasma lipoprotein particle ( 0.00451647780659392 ); GO:0002763 positive regulation of myeloid leukocyte differentiation ( 0.00526763491852544 ); GO:0019218 regulation of steroid metabolic process ( 0.00526763491852544 ); GO:0045834 positive regulation of lipid metabolic process ( 0.00526763491852544 ); GO:0010743 regulation of foam cell differentiation ( 0.00551791983325034 ); GO:0046890 regulation of lipid biosynthetic process ( 0.00551791983325034 ); GO:0010742 foam cell differentiation ( 0.00676858882979892 ); GO:0030665 clathrin coated vesicle membrane ( 0.00676858882979892 ); GO:0016917 GABA receptor activity ( 0.00676858882979892 ); GO:0042632 cholesterol homeostasis ( 0.00726850396774359 ); GO:0055092 sterol homeostasis ( 0.00726850396774359 ); GO:0006695 cholesterol biosynthetic process ( 0.00751838603984234 ); GO:0009791 post-embryonic development ( 0.00751838603984234 ); GO:0045649 regulation of macrophage differentiation ( 0.00751838603984234 ); GO:0030139 endocytic vesicle ( 0.00751838603984234 ); GO:0008066 glutamate receptor activity ( 0.00751838603984234 ); GO:0000060 protein import into nucleus, translocation ( 0.00776821779082648 ); GO:0009116 nucleoside metabolic process ( 0.00776821779082648 ); GO:0045639 positive regulation of myeloid cell differentiation ( 0.00776821779082648 ); GO:0006641 triglyceride metabolic process ( 0.00801799922829738 ); GO:0007194 negative regulation of adenylate cyclase activity ( 0.00801799922829738 ); GO:0031280 negative regulation of cyclase activity ( 0.00801799922829738 ); GO:0033500 carbohydrate homeostasis ( 0.00801799922829738 ); GO:0042593 glucose homeostasis ( 0.00801799922829738 ); GO:0051350 negative regulation of lyase activity ( 0.00801799922829738 ); GO:0009166 nucleotide catabolic process ( 0.00826773035985462 ); GO:0042592 homeostatic process ( 0.00830134640080348 ); GO:0030301 cholesterol transport ( 0.00851741119309746 ); GO:0006220 pyrimidine nucleotide metabolic process ( 0.00876704173562382 ); GO:0015918 sterol transport ( 0.00876704173562382 ); GO:0055088 lipid homeostasis ( 0.00901662199503184 ); GO:0006638 neutral lipid metabolic process ( 0.00926615197891789 ); GO:0006639 acylglycerol metabolic process ( 0.00926615197891789 ); GO:0046486 glycerolipid metabolic process ( 0.00951563169487812 ); GO:0030662 coated vesicle membrane ( 0.00951563169487812 ); GO:0006662 glycerol ether metabolic process ( 0.00976506115050757 ); GO:0016126 sterol biosynthetic process ( 0.00976506115050757 ); ----------------KEGG-------------- hsa00983 Drug metabolism - other enzymes ( 0.0110114547894771 ); hsa00240 Pyrimidine metabolism ( 0.0226663222395764 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3641 ========================= ----------------C2-------------- REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL ( 0.00251117347179275 ); REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL ( 0.00376486698322764 ); KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS ( 0.00401545434941553 ); REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS ( 0.00476691391280593 ); REACTOME_PEROXISOMAL_LIPID_METABOLISM ( 0.00501729961424691 ); REACTOME_METABOLISM_OF_BILE_ACIDS_AND_BILE_SALTS ( 0.00676858882979892 ); ----------------C3-------------- YTTCCNNNGGAMR_UNKNOWN ( 0.00926615197891789 ); V$CDPCR3_01 ( 0.00951563169487812 ); ----------------C4-------------- GNF2_CDH3 ( 0.00601833852446665 ); GNF2_SERPINB5 ( 0.006268472316171 ); module_500 ( 0.00726850396774359 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0008111 alpha-methylacyl-CoA racemase activity ( ); GO:0016854 racemase and epimerase activity ( ); GO:0001608 nucleotide receptor activity, G-protein coupled ( ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( ); GO:0001614 purinergic nucleotide receptor activity ( ); GO:0016502 nucleotide receptor activity ( ); ----------------GO-------------- GO:0008111 alpha-methylacyl-CoA racemase activity ( 0.000251344694113254 ); GO:0016854 racemase and epimerase activity ( 0.003012802242921 ); GO:0001608 nucleotide receptor activity, G-protein coupled ( 0.00676858882979892 ); GO:0045028 purinergic nucleotide receptor activity, G-protein coupled ( 0.00676858882979892 ); GO:0001614 purinergic nucleotide receptor activity ( 0.00851741119309746 ); GO:0016502 nucleotide receptor activity ( 0.00851741119309746 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3652 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- POSITIVE_REGULATION_OF_MAPKKK_CASCADE ( 0.00276201309019264 ); REGULATION_OF_JNK_CASCADE ( 0.003012802242921 ); REGULATION_OF_MAPKKK_CASCADE ( 0.00501729961424691 ); ----------------GOSLIM-------------- GO:0032872 regulation of stress-activated MAPK cascade ( ); GO:0032874 positive regulation of stress-activated MAPK cascade ( ); GO:0051403 stress-activated MAPK cascade ( ); GO:0009967 positive regulation of signal transduction ( ); GO:0010647 positive regulation of cell communication ( ); GO:0042803 protein homodimerization activity ( ); GO:0050700 CARD domain binding ( ); GO:0004931 ATP-gated cation channel activity ( ); GO:0010524 positive regulation of calcium ion transport into cytosol ( ); GO:0010522 regulation of calcium ion transport into cytosol ( ); GO:0046330 positive regulation of JNK cascade ( ); GO:0050850 positive regulation of calcium-mediated signaling ( ); GO:0050848 regulation of calcium-mediated signaling ( ); GO:0051928 positive regulation of calcium ion transport ( ); GO:0043270 positive regulation of ion transport ( ); GO:0046328 regulation of JNK cascade ( ); GO:0046983 protein dimerization activity ( ); GO:0042802 identical protein binding ( ); GO:0060402 calcium ion transport into cytosol ( ); GO:0060401 cytosolic calcium ion transport ( ); GO:0043410 positive regulation of MAPKKK cascade ( ); GO:0051924 regulation of calcium ion transport ( ); GO:0008430 selenium binding ( ); GO:0001614 purinergic nucleotide receptor activity ( ); GO:0016502 nucleotide receptor activity ( ); GO:0009966 regulation of signal transduction ( ); GO:0019722 calcium-mediated signaling ( ); GO:0043269 regulation of ion transport ( ); ----------------GO-------------- GO:0032872 regulation of stress-activated MAPK cascade ( 0.000502638846362036 ); GO:0032874 positive regulation of stress-activated MAPK cascade ( 0.000502638846362036 ); GO:0051403 stress-activated MAPK cascade ( 0.00100507555575524 ); GO:0009967 positive regulation of signal transduction ( 0.00107588991819013 ); GO:0010647 positive regulation of cell communication ( 0.00120183910470069 ); GO:0042803 protein homodimerization activity ( 0.00132326938337888 ); GO:0050700 CARD domain binding ( 0.00150731018915273 ); GO:0004931 ATP-gated cation channel activity ( 0.00175835174640371 ); GO:0010524 positive regulation of calcium ion transport into cytosol ( 0.00200934280751552 ); GO:0010522 regulation of calcium ion transport into cytosol ( 0.00251117347179275 ); GO:0046330 positive regulation of JNK cascade ( 0.00251117347179275 ); GO:0050850 positive regulation of calcium-mediated signaling ( 0.00251117347179275 ); GO:0050848 regulation of calcium-mediated signaling ( 0.00276201309019264 ); GO:0051928 positive regulation of calcium ion transport ( 0.00351422918182454 ); GO:0043270 positive regulation of ion transport ( 0.00376486698322764 ); GO:0046328 regulation of JNK cascade ( 0.00376486698322764 ); GO:0046983 protein dimerization activity ( 0.00381743645120667 ); GO:0042802 identical protein binding ( 0.00505097685073922 ); GO:0060402 calcium ion transport into cytosol ( 0.00526763491852544 ); GO:0060401 cytosolic calcium ion transport ( 0.00551791983325034 ); GO:0043410 positive regulation of MAPKKK cascade ( 0.00701857156693042 ); GO:0051924 regulation of calcium ion transport ( 0.00726850396774359 ); GO:0008430 selenium binding ( 0.00751838603984234 ); GO:0001614 purinergic nucleotide receptor activity ( 0.00851741119309746 ); GO:0016502 nucleotide receptor activity ( 0.00851741119309746 ); GO:0009966 regulation of signal transduction ( 0.00905285695574933 ); GO:0019722 calcium-mediated signaling ( 0.00926615197891789 ); GO:0043269 regulation of ion transport ( 0.00976506115050757 ); ----------------KEGG-------------- ( 0.0439501834482882 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3667 ========================= ----------------C2-------------- ( 0.00601833852446665 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0007005 mitochondrion organization ( 0.000491912432025427 ); GO:0006851 mitochondrial calcium ion transport ( 0.000491912432025427 ); GO:0048312 intracellular distribution of mitochondria ( 0.000491912432025427 ); GO:0001306 age-dependent response to oxidative stress ( 0.000491912432025427 ); GO:0007571 age-dependent general metabolic decline ( 0.000491912432025427 ); GO:0048311 mitochondrion distribution ( 0.000491912432025427 ); GO:0051933 amino acid uptake during transmission of nerve impulse ( 0.000491912432025427 ); GO:0051935 glutamate uptake during transmission of nerve impulse ( 0.000491912432025427 ); GO:0043090 amino acid import ( 0.000491912432025427 ); GO:0043092 L-amino acid import ( 0.000491912432025427 ); GO:0051938 L-glutamate import ( 0.000491912432025427 ); GO:0060052 neurofilament cytoskeleton organization ( 0.000491912432025427 ); GO:0046513 ceramide biosynthetic process ( 0.000491912432025427 ); GO:0050884 neuromuscular process controlling posture ( 0.000491912432025427 ); GO:0008306 associative learning ( 0.000491912432025427 ); GO:0035176 social behavior ( 0.000491912432025427 ); GO:0046520 sphingoid biosynthetic process ( 0.000491912432025427 ); GO:0051646 mitochondrion localization ( 0.000491912432025427 ); GO:0021522 spinal cord motor neuron differentiation ( 0.000491912432025427 ); GO:0045861 negative regulation of proteolysis ( 0.000491912432025427 ); GO:0021517 ventral spinal cord development ( 0.000491912432025427 ); GO:0001504 neurotransmitter uptake ( 0.000491912432025427 ); GO:0007030 Golgi organization ( 0.000491912432025427 ); GO:0050879 multicellular organismal movement ( 0.000491912432025427 ); GO:0050881 musculoskeletal movement ( 0.000491912432025427 ); GO:0015800 acidic amino acid transport ( 0.000491912432025427 ); GO:0015813 L-glutamate transport ( 0.000491912432025427 ); GO:0007628 adult walking behavior ( 0.000491912432025427 ); GO:0045104 intermediate filament cytoskeleton organization ( 0.000491912432025427 ); GO:0033116 ER-Golgi intermediate compartment membrane ( 0.000491912432025427 ); GO:0015807 L-amino acid transport ( 0.000491912432025427 ); GO:0051705 behavioral interaction between organisms ( 0.000491912432025427 ); GO:0045103 intermediate filament-based process ( 0.000491912432025427 ); GO:0021515 cell differentiation in spinal cord ( 0.000491912432025427 ); GO:0007040 lysosome organization ( 0.000491912432025427 ); GO:0045494 photoreceptor cell maintenance ( 0.000491912432025427 ); GO:0030148 sphingolipid biosynthetic process ( 0.000491912432025427 ); GO:0007033 vacuole organization ( 0.000491912432025427 ); GO:0060041 retina development in camera-type eye ( 0.000491912432025427 ); GO:0007006 mitochondrial membrane organization ( 0.000491912432025427 ); GO:0050885 neuromuscular process controlling balance ( 0.000491912432025427 ); GO:0021510 spinal cord development ( 0.000491912432025427 ); GO:0048468 cell development ( 0.000491912432025427 ); GO:0006672 ceramide metabolic process ( 0.000491912432025427 ); GO:0008344 adult locomotory behavior ( 0.000491912432025427 ); GO:0030162 regulation of proteolysis ( 0.000491912432025427 ); GO:0007267 cell-cell signaling ( 0.000491912432025427 ); GO:0033500 carbohydrate homeostasis ( 0.000491912432025427 ); GO:0042593 glucose homeostasis ( 0.000491912432025427 ); GO:0007612 learning ( 0.000491912432025427 ); GO:0042592 homeostatic process ( 0.000491912432025427 ); GO:0046519 sphingoid metabolic process ( 0.000491912432025427 ); GO:0019722 calcium-mediated signaling ( 0.000491912432025427 ); ----------------GO-------------- GO:0007005 mitochondrion organization ( 0.00020512295778053 ); GO:0006851 mitochondrial calcium ion transport ( 0.000251344694113254 ); GO:0048312 intracellular distribution of mitochondria ( 0.000251344694113254 ); GO:0001306 age-dependent response to oxidative stress ( 0.000502638846362036 ); GO:0007571 age-dependent general metabolic decline ( 0.000502638846362036 ); GO:0048311 mitochondrion distribution ( 0.000502638846362036 ); GO:0051933 amino acid uptake during transmission of nerve impulse ( 0.000502638846362036 ); GO:0051935 glutamate uptake during transmission of nerve impulse ( 0.000502638846362036 ); GO:0043090 amino acid import ( 0.000753882464368472 ); GO:0043092 L-amino acid import ( 0.000753882464368472 ); GO:0051938 L-glutamate import ( 0.000753882464368472 ); GO:0060052 neurofilament cytoskeleton organization ( 0.00125621812814281 ); GO:0046513 ceramide biosynthetic process ( 0.00200934280751552 ); GO:0050884 neuromuscular process controlling posture ( 0.00200934280751552 ); GO:0008306 associative learning ( 0.00226028338010609 ); GO:0035176 social behavior ( 0.00226028338010609 ); GO:0046520 sphingoid biosynthetic process ( 0.00226028338010609 ); GO:0051646 mitochondrion localization ( 0.00251117347179275 ); GO:0021522 spinal cord motor neuron differentiation ( 0.00276201309019264 ); GO:0045861 negative regulation of proteolysis ( 0.00276201309019264 ); GO:0021517 ventral spinal cord development ( 0.003012802242921 ); GO:0001504 neurotransmitter uptake ( 0.00326354093759351 ); GO:0007030 Golgi organization ( 0.00326354093759351 ); GO:0050879 multicellular organismal movement ( 0.00326354093759351 ); GO:0050881 musculoskeletal movement ( 0.00326354093759351 ); GO:0015800 acidic amino acid transport ( 0.00351422918182454 ); GO:0015813 L-glutamate transport ( 0.00351422918182454 ); GO:0007628 adult walking behavior ( 0.00376486698322764 ); GO:0045104 intermediate filament cytoskeleton organization ( 0.00376486698322764 ); GO:0033116 ER-Golgi intermediate compartment membrane ( 0.00376486698322764 ); GO:0015807 L-amino acid transport ( 0.00401545434941553 ); GO:0051705 behavioral interaction between organisms ( 0.00401545434941553 ); GO:0045103 intermediate filament-based process ( 0.00426599128800043 ); GO:0021515 cell differentiation in spinal cord ( 0.00451647780659392 ); GO:0007040 lysosome organization ( 0.00501729961424691 ); GO:0045494 photoreceptor cell maintenance ( 0.00501729961424691 ); GO:0030148 sphingolipid biosynthetic process ( 0.00526763491852544 ); GO:0007033 vacuole organization ( 0.00551791983325034 ); GO:0060041 retina development in camera-type eye ( 0.00551791983325034 ); GO:0007006 mitochondrial membrane organization ( 0.00601833852446665 ); GO:0050885 neuromuscular process controlling balance ( 0.00651855574874693 ); GO:0021510 spinal cord development ( 0.00701857156693042 ); GO:0048468 cell development ( 0.00719320401577162 ); GO:0006672 ceramide metabolic process ( 0.00776821779082648 ); GO:0008344 adult locomotory behavior ( 0.00776821779082648 ); GO:0030162 regulation of proteolysis ( 0.00776821779082648 ); GO:0007267 cell-cell signaling ( 0.0079236941154784 ); GO:0033500 carbohydrate homeostasis ( 0.00801799922829738 ); GO:0042593 glucose homeostasis ( 0.00801799922829738 ); GO:0007612 learning ( 0.00826773035985462 ); GO:0042592 homeostatic process ( 0.00830134640080348 ); GO:0046519 sphingoid metabolic process ( 0.00851741119309746 ); GO:0019722 calcium-mediated signaling ( 0.00926615197891789 ); ----------------KEGG-------------- ( 0.00576815436602829 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3715 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( 0.00851741119309746 ); ----------------C5-------------- ( 0.00451647780659392 ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( 0.00251117347179275 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- PUM2_PAR-CLIP_(Hafner_2010) ( 0.00597188741869525 ); IGF2BP1-3_PAR-CLIP_(Hafner_2010) ( 0.0295305131132315 ); TDP-43_iCLIP_(Tollervey_2011) ( 0.0295566107048276 ); SF2/ASF_CLIP-SEQ_(Sanford_2009) ( 0.0368836102813566 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3730 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- module_560 ( 0.00276201309019264 ); module_465 ( 0.00376486698322764 ); module_455 ( 0.00876704173562382 ); ----------------C5-------------- ( 0.00120183910470069 ); ----------------GOSLIM-------------- GO:0000793 condensed chromosome ( 0.00647177810185883 ); GO:0000775 chromosome, centromeric region ( 0.00647177810185883 ); GO:0005721 centromeric heterochromatin ( 0.00647177810185883 ); GO:0044427 chromosomal part ( 0.00647177810185883 ); GO:0008105 asymmetric protein localization ( 0.00647177810185883 ); GO:0005694 chromosome ( 0.00647177810185883 ); GO:0042384 cilium assembly ( 0.00647177810185883 ); GO:0000792 heterochromatin ( 0.00647177810185883 ); GO:0007368 determination of left/right symmetry ( 0.00647177810185883 ); GO:0009799 determination of symmetry ( 0.00647177810185883 ); GO:0009855 determination of bilateral symmetry ( 0.00647177810185883 ); GO:0030286 dynein complex ( 0.00647177810185883 ); GO:0009953 dorsal/ventral pattern formation ( 0.00647177810185883 ); GO:0000777 condensed chromosome kinetochore ( 0.00647177810185883 ); GO:0043228 non-membrane-bounded organelle ( 0.00647177810185883 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.00647177810185883 ); GO:0016787 hydrolase activity ( 0.00647177810185883 ); ----------------GO-------------- GO:0000793 condensed chromosome ( 0.000162458705356162 ); GO:0000775 chromosome, centromeric region ( 0.000174740706787265 ); GO:0005721 centromeric heterochromatin ( 0.000753882464368472 ); GO:0044427 chromosomal part ( 0.00179956506179353 ); GO:0008105 asymmetric protein localization ( 0.00251117347179275 ); GO:0005694 chromosome ( 0.00294682691306444 ); GO:0042384 cilium assembly ( 0.00426599128800043 ); GO:0000792 heterochromatin ( 0.00501729961424691 ); GO:0007368 determination of left/right symmetry ( 0.00676858882979892 ); GO:0009799 determination of symmetry ( 0.00676858882979892 ); GO:0009855 determination of bilateral symmetry ( 0.00676858882979892 ); GO:0030286 dynein complex ( 0.00726850396774359 ); GO:0009953 dorsal/ventral pattern formation ( 0.00851741119309746 ); GO:0000777 condensed chromosome kinetochore ( 0.00951563169487812 ); GO:0043228 non-membrane-bounded organelle ( 0.00988888201141563 ); GO:0043232 intracellular non-membrane-bounded organelle ( 0.00988888201141563 ); GO:0016787 hydrolase activity ( 0.00994245070504235 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( 0.00501729961424691 ); ----------------RBP-------------- ( 0.0295305131132315 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3736 ========================= ----------------C2-------------- REACTOME_PHOSPHORYLATION_OF_THE_APC ( 0.00401545434941553 ); REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B ( 0.00426599128800043 ); REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE ( 0.00426599128800043 ); REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX ( 0.00451647780659392 ); REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES ( 0.00451647780659392 ); ----------------C3-------------- ( ); ----------------C4-------------- module_4 ( 0.00526763491852544 ); module_16 ( 0.0057405370172841 ); module_82 ( 0.00601833852446665 ); module_278 ( 0.00851741119309746 ); ----------------C5-------------- ( 0.00951563169487812 ); ----------------GOSLIM-------------- GO:0042254 ribosome biogenesis ( 0.000399326668245998 ); GO:0042296 ISG15 ligase activity ( 0.0057634771154976 ); GO:0015037 peptide disulfide oxidoreductase activity ( 0.00813789656587668 ); GO:0015038 glutathione disulfide oxidoreductase activity ( 0.000399326668245998 ); GO:0005829 cytosol ( 0.0057634771154976 ); GO:0032020 ISG15-protein conjugation ( 0.00813789656587668 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.000399326668245998 ); GO:0015035 protein disulfide oxidoreductase activity ( 0.0057634771154976 ); GO:0015036 disulfide oxidoreductase activity ( 0.00813789656587668 ); GO:0016667 oxidoreductase activity, acting on sulfur group of donors ( 0.000399326668245998 ); ----------------GO-------------- GO:0042254 ribosome biogenesis ( 0.000273111610322408 ); GO:0042296 ISG15 ligase activity ( 0.000502638846362036 ); GO:0015037 peptide disulfide oxidoreductase activity ( 0.000753882464368472 ); GO:0015038 glutathione disulfide oxidoreductase activity ( 0.000753882464368472 ); GO:0005829 cytosol ( 0.000887288904892929 ); GO:0032020 ISG15-protein conjugation ( 0.00100507555575524 ); GO:0022613 ribonucleoprotein complex biogenesis ( 0.00112754035922014 ); GO:0015035 protein disulfide oxidoreductase activity ( 0.00326354093759351 ); GO:0015036 disulfide oxidoreductase activity ( 0.00426599128800043 ); GO:0016667 oxidoreductase activity, acting on sulfur group of donors ( 0.00901662199503184 ); ----------------KEGG-------------- ( 0.0324985730389302 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3746 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0005797 Golgi medial cisterna ( ); GO:0007030 Golgi organization ( ); GO:0031985 Golgi cisterna ( ); GO:0031984 organelle subcompartment ( ); GO:0005795 Golgi stack ( ); ----------------GO-------------- GO:0005797 Golgi medial cisterna ( 0.000502638846362036 ); GO:0007030 Golgi organization ( 0.00326354093759351 ); GO:0031985 Golgi cisterna ( 0.00401545434941553 ); GO:0031984 organelle subcompartment ( 0.00451647780659392 ); GO:0005795 Golgi stack ( 0.00676858882979892 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3776 ========================= ----------------C2-------------- KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE ( 0.00376486698322764 ); BIOCARTA_IL1R_PATHWAY ( 0.00801799922829738 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( 0.00851741119309746 ); ----------------GOSLIM-------------- GO:0004704 NF-kappaB-inducing kinase activity ( ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( ); GO:0043433 negative regulation of transcription factor activity ( ); GO:0051092 positive regulation of NF-kappaB transcription factor activity ( ); GO:0008378 galactosyltransferase activity ( ); GO:0043392 negative regulation of DNA binding ( ); GO:0051100 negative regulation of binding ( ); GO:0051091 positive regulation of transcription factor activity ( ); ----------------GO-------------- GO:0004704 NF-kappaB-inducing kinase activity ( 0.00125621812814281 ); GO:0031663 lipopolysaccharide-mediated signaling pathway ( 0.00200934280751552 ); GO:0043433 negative regulation of transcription factor activity ( 0.00651855574874693 ); GO:0051092 positive regulation of NF-kappaB transcription factor activity ( 0.00701857156693042 ); GO:0008378 galactosyltransferase activity ( 0.00726850396774359 ); GO:0043392 negative regulation of DNA binding ( 0.00776821779082648 ); GO:0051100 negative regulation of binding ( 0.00851741119309746 ); GO:0051091 positive regulation of transcription factor activity ( 0.00901662199503184 ); ----------------KEGG-------------- hsa00533 Keratan sulfate biosynthesis ( 0.00401545434941553 ); hsa04210 Apoptosis ( 0.0219256935355265 ); hsa01030 Glycan structures - biosynthesis 1 ( 0.0293118121905235 ); ----------------CARTA-------------- ( 0.00326354093759351 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3792 ========================= ----------------C2-------------- ( 0.00651855574874693 ); ----------------C3-------------- ( 0.000664605465405503 ); ----------------C4-------------- ( ); ----------------C5-------------- OXIDOREDUCTASE_ACTIVITY__ACTING_ON_SULFUR_GROUP_OF_DONORS ( 0.00251117347179275 ); TRANSCRIPTION_FACTOR_ACTIVITY ( 0.0028313106920137 ); PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT ( 0.003012802242921 ); TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY ( 0.00476691391280593 ); DNA_BINDING ( 0.0081926052522265 ); ----------------GOSLIM-------------- GO:0021594 rhombomere formation ( ); GO:0021660 rhombomere 3 formation ( ); GO:0021664 rhombomere 5 morphogenesis ( ); GO:0021666 rhombomere 5 formation ( ); GO:0021593 rhombomere morphogenesis ( ); GO:0021658 rhombomere 3 morphogenesis ( ); GO:0000318 protein-methionine-R-oxide reductase activity ( ); GO:0021561 facial nerve development ( ); GO:0021569 rhombomere 3 development ( ); GO:0021604 cranial nerve structural organization ( ); GO:0021610 facial nerve morphogenesis ( ); GO:0021612 facial nerve structural organization ( ); GO:0030091 protein repair ( ); GO:0035283 central nervous system segmentation ( ); GO:0035284 brain segmentation ( ); GO:0021571 rhombomere 5 development ( ); GO:0021783 preganglionic parasympathetic nervous system development ( ); GO:0008113 peptide-methionine-(S)-S-oxide reductase activity ( ); GO:0048486 parasympathetic nervous system development ( ); GO:0048532 anatomical structure arrangement ( ); GO:0014037 Schwann cell differentiation ( ); GO:0021546 rhombomere development ( ); GO:0021602 cranial nerve morphogenesis ( ); GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor ( ); GO:0007622 rhythmic behavior ( ); GO:0007638 mechanosensory behavior ( ); GO:0008045 motor axon guidance ( ); GO:0048483 autonomic nervous system development ( ); GO:0021545 cranial nerve development ( ); GO:0048168 regulation of neuronal synaptic plasticity ( ); GO:0005001 transmembrane receptor protein tyrosine phosphatase activity ( ); GO:0019198 transmembrane receptor protein phosphatase activity ( ); GO:0032868 response to insulin stimulus ( ); GO:0021675 nerve development ( ); GO:0048167 regulation of synaptic plasticity ( ); GO:0042552 myelination ( ); GO:0007422 peripheral nervous system development ( ); GO:0009612 response to mechanical stimulus ( ); GO:0007272 ensheathment of neurons ( ); GO:0008366 axon ensheathment ( ); GO:0035282 segmentation ( ); GO:0019228 regulation of action potential in neuron ( ); GO:0016667 oxidoreductase activity, acting on sulfur group of donors ( ); GO:0030902 hindbrain development ( ); GO:0043434 response to peptide hormone stimulus ( ); ----------------GO-------------- GO:0021594 rhombomere formation ( 0.000251344694113254 ); GO:0021660 rhombomere 3 formation ( 0.000251344694113254 ); GO:0021664 rhombomere 5 morphogenesis ( 0.000251344694113254 ); GO:0021666 rhombomere 5 formation ( 0.000251344694113254 ); GO:0021593 rhombomere morphogenesis ( 0.000502638846362036 ); GO:0021658 rhombomere 3 morphogenesis ( 0.000502638846362036 ); GO:0000318 protein-methionine-R-oxide reductase activity ( 0.000502638846362036 ); GO:0021561 facial nerve development ( 0.000753882464368472 ); GO:0021569 rhombomere 3 development ( 0.000753882464368472 ); GO:0021604 cranial nerve structural organization ( 0.000753882464368472 ); GO:0021610 facial nerve morphogenesis ( 0.000753882464368472 ); GO:0021612 facial nerve structural organization ( 0.000753882464368472 ); GO:0030091 protein repair ( 0.000753882464368472 ); GO:0035283 central nervous system segmentation ( 0.000753882464368472 ); GO:0035284 brain segmentation ( 0.000753882464368472 ); GO:0021571 rhombomere 5 development ( 0.00100507555575524 ); GO:0021783 preganglionic parasympathetic nervous system development ( 0.00100507555575524 ); GO:0008113 peptide-methionine-(S)-S-oxide reductase activity ( 0.00100507555575524 ); GO:0048486 parasympathetic nervous system development ( 0.00125621812814281 ); GO:0048532 anatomical structure arrangement ( 0.00125621812814281 ); GO:0014037 Schwann cell differentiation ( 0.00150731018915273 ); GO:0021546 rhombomere development ( 0.00150731018915273 ); GO:0021602 cranial nerve morphogenesis ( 0.00175835174640371 ); GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor ( 0.00175835174640371 ); GO:0007622 rhythmic behavior ( 0.00200934280751552 ); GO:0007638 mechanosensory behavior ( 0.00200934280751552 ); GO:0008045 motor axon guidance ( 0.00226028338010609 ); GO:0048483 autonomic nervous system development ( 0.00276201309019264 ); GO:0021545 cranial nerve development ( 0.00351422918182454 ); GO:0048168 regulation of neuronal synaptic plasticity ( 0.00376486698322764 ); GO:0005001 transmembrane receptor protein tyrosine phosphatase activity ( 0.00426599128800043 ); GO:0019198 transmembrane receptor protein phosphatase activity ( 0.00426599128800043 ); GO:0032868 response to insulin stimulus ( 0.00476691391280593 ); GO:0021675 nerve development ( 0.00501729961424691 ); GO:0048167 regulation of synaptic plasticity ( 0.006268472316171 ); GO:0042552 myelination ( 0.00701857156693042 ); GO:0007422 peripheral nervous system development ( 0.00726850396774359 ); GO:0009612 response to mechanical stimulus ( 0.00726850396774359 ); GO:0007272 ensheathment of neurons ( 0.00751838603984234 ); GO:0008366 axon ensheathment ( 0.00751838603984234 ); GO:0035282 segmentation ( 0.00801799922829738 ); GO:0019228 regulation of action potential in neuron ( 0.00901662199503184 ); GO:0016667 oxidoreductase activity, acting on sulfur group of donors ( 0.00901662199503184 ); GO:0030902 hindbrain development ( 0.00951563169487812 ); GO:0043434 response to peptide hormone stimulus ( 0.00951563169487812 ); ----------------KEGG-------------- ( 0.0100144403534012 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3793 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- ( ); ----------------GO-------------- ( ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.026662093032415 ); ============================ group3798 ========================= ----------------C2-------------- REACTOME_ETHANOL_OXIDATION ( 0.00251117347179275 ); REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS ( 0.00426599128800043 ); ----------------C3-------------- ( 0.00555857882150881 ); ----------------C4-------------- module_514 ( 0.00251117347179275 ); module_373 ( 0.00551791983325034 ); GNF2_IGF1 ( 0.00651855574874693 ); module_200 ( 0.00676858882979892 ); module_382 ( 0.00701857156693042 ); module_23 ( 0.00719320401577162 ); module_524 ( 0.00751838603984234 ); GNF2_IGFBP1 ( 0.00876704173562382 ); module_286 ( 0.00926615197891789 ); ----------------C5-------------- INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_BINDING ( 0.00251117347179275 ); INSULIN_RECEPTOR_SIGNALING_PATHWAY ( 0.00451647780659392 ); REGULATION_OF_GENE_EXPRESSION__EPIGENETIC ( 0.00751838603984234 ); ----------------GOSLIM-------------- GO:0006349 genetic imprinting ( ); GO:0001881 receptor recycling ( ); GO:0004024 alcohol dehydrogenase activity, zinc-dependent ( ); GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ( ); GO:0004022 alcohol dehydrogenase activity ( ); GO:0005159 insulin-like growth factor receptor binding ( ); GO:0007167 enzyme linked receptor protein signaling pathway ( ); GO:0005158 insulin receptor binding ( ); GO:0043112 receptor metabolic process ( ); GO:0008286 insulin receptor signaling pathway ( ); GO:0007173 epidermal growth factor receptor signaling pathway ( ); ----------------GO-------------- GO:0006349 genetic imprinting ( 0.00100507555575524 ); GO:0001881 receptor recycling ( 0.00125621812814281 ); GO:0004024 alcohol dehydrogenase activity, zinc-dependent ( 0.00125621812814281 ); GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ( 0.00125632722071151 ); GO:0004022 alcohol dehydrogenase activity ( 0.00200934280751552 ); GO:0005159 insulin-like growth factor receptor binding ( 0.00251117347179275 ); GO:0007167 enzyme linked receptor protein signaling pathway ( 0.00309861505492276 ); GO:0005158 insulin receptor binding ( 0.00526763491852544 ); GO:0043112 receptor metabolic process ( 0.00701857156693042 ); GO:0008286 insulin receptor signaling pathway ( 0.00801799922829738 ); GO:0007173 epidermal growth factor receptor signaling pathway ( 0.00876704173562382 ); ----------------KEGG-------------- hsa00624 1- and 2-Methylnaphthalene degradation ( 0.003012802242921 ); hsa00641 3-Chloroacrylic acid degradation ( 0.00351422918182454 ); hsa00120 Bile acid biosynthesis ( 0.00801799922829738 ); hsa00350 Tyrosine metabolism ( 0.0112605828425807 ); hsa00071 Fatty acid metabolism ( 0.011509660688499 ); hsa00830 Retinol metabolism ( 0.0139976794217257 ); hsa00010 Glycolysis / Gluconeogenesis ( 0.015488084236395 ); hsa00980 Metabolism of xenobiotics by cytochrome P450 ( 0.015488084236395 ); hsa00982 Drug metabolism - cytochrome P450 ( 0.0159844851342638 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3812 ========================= ----------------C2-------------- BIOCARTA_CTCF_PATHWAY ( 0.00576815436602829 ); KEGG_THYROID_CANCER ( 0.00726850396774359 ); KEGG_BASE_EXCISION_REPAIR ( 0.00851741119309746 ); BIOCARTA_BCR_PATHWAY ( 0.00851741119309746 ); KEGG_DNA_REPLICATION ( 0.00901662199503184 ); ----------------C3-------------- ( 0.00101547441313893 ); ----------------C4-------------- module_33 ( 0.00332433381933917 ); module_404 ( 0.00651855574874693 ); module_489 ( 0.00751838603984234 ); ----------------C5-------------- DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY ( 0.00351422918182454 ); DNA_POLYMERASE_ACTIVITY ( 0.00451647780659392 ); LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY ( 0.006268472316171 ); ----------------GOSLIM-------------- GO:0004886 retinoid-X receptor activity ( ); GO:0003708 retinoic acid receptor activity ( ); GO:0043565 sequence-specific DNA binding ( ); GO:0003887 DNA-directed DNA polymerase activity ( ); GO:0034061 DNA polymerase activity ( ); ----------------GO-------------- GO:0004886 retinoid-X receptor activity ( 0.00251117347179275 ); GO:0003708 retinoic acid receptor activity ( 0.00326354093759351 ); GO:0043565 sequence-specific DNA binding ( 0.00625521314582036 ); GO:0003887 DNA-directed DNA polymerase activity ( 0.00726850396774359 ); GO:0034061 DNA polymerase activity ( 0.00826773035985462 ); ----------------KEGG-------------- hsa05216 Thyroid cancer ( 0.00726850396774359 ); hsa03410 Base excision repair ( 0.00851741119309746 ); hsa03030 DNA replication ( 0.00901662199503184 ); hsa03420 Nucleotide excision repair ( 0.0107622765215984 ); hsa05223 Non-small cell lung cancer ( 0.0135004769077131 ); hsa04662 B cell receptor signaling pathway ( 0.0162326104847266 ); hsa04920 Adipocytokine signaling pathway ( 0.0164806857796417 ); hsa03320 PPAR signaling pathway ( 0.0169766862331231 ); hsa05222 Small cell lung cancer ( 0.0214316916710394 ); hsa00240 Pyrimidine metabolism ( 0.0226663222395764 ); hsa00230 Purine metabolism ( 0.0364092446831654 ); ----------------CARTA-------------- gata3pathway ( 0.00376486698322764 ); hbxpathway ( 0.00676858882979892 ); hcmvpathway ( 0.00751838603984234 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0184634870479424 ); ----------------ARE-------------- ( ); ============================ group3817 ========================= ----------------C2-------------- REACTOME_RAS_ACTIVATION_UOPN_CA2+_INFUX_THROUGH_NMDA_RECEPTOR ( 0.00451647780659392 ); REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS ( 0.00651855574874693 ); REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS ( 0.00801799922829738 ); REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS ( 0.00901662199503184 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- ( 0.0078569449420589 ); ----------------GO-------------- ( 0.00451647780659392 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( 0.0483070795264641 ); ============================ group3818 ========================= ----------------C2-------------- KEGG_NON_HOMOLOGOUS_END_JOINING ( 0.00326354093759351 ); KEGG_PRIMARY_IMMUNODEFICIENCY ( 0.00876704173562382 ); ----------------C3-------------- ( ); ----------------C4-------------- module_396 ( 0.003012802242921 ); module_489 ( 0.00751838603984234 ); module_511 ( 0.00851741119309746 ); ----------------C5-------------- REGULATION_OF_CELLULAR_PH ( 0.00251117347179275 ); CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS ( 0.00276201309019264 ); REGULATION_OF_PH ( 0.00326354093759351 ); MONOVALENT_INORGANIC_CATION_HOMEOSTASIS ( 0.00351422918182454 ); PDZ_DOMAIN_BINDING ( 0.00351422918182454 ); CHLORIDE_CHANNEL_ACTIVITY ( 0.00476691391280593 ); ANION_CHANNEL_ACTIVITY ( 0.00501729961424691 ); VESICLE_MEMBRANE ( 0.00701857156693042 ); ----------------GOSLIM-------------- GO:0048388 endosomal lumen acidification ( ); GO:0051452 intracellular pH reduction ( ); GO:0045851 pH reduction ( ); GO:0007032 endosome organization ( ); GO:0051453 regulation of intracellular pH ( ); GO:0030641 regulation of cellular pH ( ); GO:0030004 cellular monovalent inorganic cation homeostasis ( ); GO:0005247 voltage-gated chloride channel activity ( ); GO:0008308 voltage-gated anion channel activity ( ); GO:0031901 early endosome membrane ( ); GO:0006885 regulation of pH ( ); GO:0030165 PDZ domain binding ( ); GO:0055067 monovalent inorganic cation homeostasis ( ); ----------------GO-------------- GO:0048388 endosomal lumen acidification ( 0.000502638846362036 ); GO:0051452 intracellular pH reduction ( 0.00200934280751552 ); GO:0045851 pH reduction ( 0.00226028338010609 ); GO:0007032 endosome organization ( 0.00251117347179275 ); GO:0051453 regulation of intracellular pH ( 0.00276201309019264 ); GO:0030641 regulation of cellular pH ( 0.003012802242921 ); GO:0030004 cellular monovalent inorganic cation homeostasis ( 0.00376486698322764 ); GO:0005247 voltage-gated chloride channel activity ( 0.00401545434941553 ); GO:0008308 voltage-gated anion channel activity ( 0.00526763491852544 ); GO:0031901 early endosome membrane ( 0.00601833852446665 ); GO:0006885 regulation of pH ( 0.00676858882979892 ); GO:0030165 PDZ domain binding ( 0.00676858882979892 ); GO:0055067 monovalent inorganic cation homeostasis ( 0.00826773035985462 ); ----------------KEGG-------------- hsa03450 Non-homologous end-joining ( 0.00326354093759351 ); hsa05340 Primary immunodeficiency ( 0.00876704173562382 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3844 ========================= ----------------C2-------------- REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS ( 0.00251117347179275 ); BIOCARTA_SET_PATHWAY ( 0.00276201309019264 ); BIOCARTA_D4GDI_PATHWAY ( 0.00326354093759351 ); BIOCARTA_CTL_PATHWAY ( 0.00351422918182454 ); BIOCARTA_CASPASE_PATHWAY ( 0.00576815436602829 ); KEGG_ALLOGRAFT_REJECTION ( 0.00876704173562382 ); KEGG_GRAFT_VERSUS_HOST_DISEASE ( 0.00976506115050757 ); ----------------C3-------------- ( 0.000773478566210962 ); ----------------C4-------------- module_379 ( 0.00090915702460193 ); module_242 ( 0.00100557135657938 ); module_181 ( 0.00204330537254419 ); module_104 ( 0.00268606580217745 ); module_575 ( 0.00276201309019264 ); GNF2_MATK ( 0.00551791983325034 ); module_41 ( 0.00681556566963876 ); GNF2_RAB7L1 ( 0.00726850396774359 ); module_45 ( 0.00734694124840342 ); module_153 ( 0.00851741119309746 ); GNF2_CD7 ( 0.00926615197891789 ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0004711 ribosomal protein S6 kinase activity ( ); GO:0048273 mitogen-activated protein kinase p38 binding ( ); GO:0051019 mitogen-activated protein kinase binding ( ); GO:0009405 pathogenesis ( ); GO:0004674 protein serine/threonine kinase activity ( ); GO:0004683 calmodulin-dependent protein kinase activity ( ); GO:0045471 response to ethanol ( ); GO:0019835 cytolysis ( ); GO:0004672 protein kinase activity ( ); GO:0044403 symbiosis, encompassing mutualism through parasitism ( ); GO:0007623 circadian rhythm ( ); GO:0006468 protein amino acid phosphorylation ( ); ----------------GO-------------- GO:0004711 ribosomal protein S6 kinase activity ( 0.000251344694113254 ); GO:0048273 mitogen-activated protein kinase p38 binding ( 0.000251344694113254 ); GO:0051019 mitogen-activated protein kinase binding ( 0.000502638846362036 ); GO:0009405 pathogenesis ( 0.00175835174640371 ); GO:0004674 protein serine/threonine kinase activity ( 0.00366792333483613 ); GO:0004683 calmodulin-dependent protein kinase activity ( 0.00451647780659392 ); GO:0045471 response to ethanol ( 0.00501729961424691 ); GO:0019835 cytolysis ( 0.00601833852446665 ); GO:0004672 protein kinase activity ( 0.00711690933418068 ); GO:0044403 symbiosis, encompassing mutualism through parasitism ( 0.00726850396774359 ); GO:0007623 circadian rhythm ( 0.00801799922829738 ); GO:0006468 protein amino acid phosphorylation ( 0.00957071521494295 ); ----------------KEGG-------------- hsa05330 Allograft rejection ( 0.00876704173562382 ); hsa05332 Graft-versus-host disease ( 0.00976506115050757 ); hsa04940 Type I diabetes mellitus ( 0.0100144403534012 ); hsa05320 Autoimmune thyroid disease ( 0.01225659305903 ); hsa04650 Natural killer cell mediated cytotoxicity ( 0.0324985730389302 ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( ); ----------------immu-------------- ( 0.0324985730389302 ); ----------------ARE-------------- ( ); ============================ group3861 ========================= ----------------C2-------------- ( ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0000145 exocyst ( ); GO:0005123 death receptor binding ( ); ----------------GO-------------- GO:0000145 exocyst ( 0.00125621812814281 ); GO:0005123 death receptor binding ( 0.00175835174640371 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ( ); ----------------RBP-------------- ( 0.0295305131132315 ); ----------------immu-------------- ( ); ----------------ARE-------------- ( ); ============================ group3886 ========================= ----------------C2-------------- BIOCARTA_ACH_PATHWAY ( 0.00401545434941553 ); REACTOME_SPHINGOLIPID_METABOLISM ( 0.00776821779082648 ); BIOCARTA_AGR_PATHWAY ( 0.00876704173562382 ); ----------------C3-------------- ( ); ----------------C4-------------- ( ); ----------------C5-------------- ( ); ----------------GOSLIM-------------- GO:0033130 acetylcholine receptor binding ( ); GO:0004758 serine C-palmitoyltransferase activity ( ); GO:0016454 C-palmitoyltransferase activity ( ); GO:0031594 neuromuscular junction ( ); GO:0016408 C-acyltransferase activity ( ); GO:0016409 palmitoyltransferase activity ( ); GO:0008603 cAMP-dependent protein kinase regulator activity ( ); GO:0016769 transferase activity, transferring nitrogenous groups ( ); ----------------GO-------------- GO:0033130 acetylcholine receptor binding ( 0.000502638846362036 ); GO:0004758 serine C-palmitoyltransferase activity ( 0.000753882464368472 ); GO:0016454 C-palmitoyltransferase activity ( 0.000753882464368472 ); GO:0031594 neuromuscular junction ( 0.00226028338010609 ); GO:0016408 C-acyltransferase activity ( 0.003012802242921 ); GO:0016409 palmitoyltransferase activity ( 0.003012802242921 ); GO:0008603 cAMP-dependent protein kinase regulator activity ( 0.00376486698322764 ); GO:0016769 transferase activity, transferring nitrogenous groups ( 0.00726850396774359 ); ----------------KEGG-------------- ( ); ----------------CARTA-------------- ceramidepathway ( 0.00200934280751552 ); melanocytepathway ( 0.00326354093759351 ); fibrinolysispathway ( 0.00451647780659392 ); metpathway ( 0.0110114547894771 ); fcer1pathway ( 0.01225659305903 ); ----------------RBP-------------- ( ); ----------------immu-------------- ( ); ----------------ARE-------------- ( );