GeneID geneLength Means-control2 Means-sample1 log2Ratio(sample1/control2) Up-Down-Regulation(sample1/control2) Probability Symbol Description KEGG Orthology GO Component GO Function GO Process 36275 2211.00 16.585 4.02 -2.04461160560909 Down 0.728140272090873 CG13183 CG13183 K04676|1|6e-06|53.1|cbr:CBG06922|SMAD, mothers against DPP 1/5/8 GO:0044464//cell part - GO:0006351//transcription, DNA-dependent 3772317 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33889 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 40637 904.00 20.675 19.24 -0.103778530288595 Down 0.208228767666094 CG11999 CG11999 K00728|1|2e-11|69.3|tgu:100227792|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] GO:0044464//cell part - - 42368 3501.54 10.27 10.025 -0.0348339449759123 Down 0.0799762250693435 CG4733 CG4733, isoform E K11583|1|0.0|1472|dme:Dmel_CG4733|protein phosphatase 2 (formerly 2A), regulatory subunit B'' - GO:0046872//metal ion binding - 42517 1356.00 7.63 7.805 0.0327155751433783 Up 0.0722493726059966 CG3353 CG3353 K11426|1|6e-11|68.9|ptr:457870|SET and MYND domain-containing protein - GO:0046914//transition metal ion binding - 47251 2056.00 29.035 26.235 -0.146300244059881 Down 0.299894333641527 Gtp-bp GTP-binding protein K13431|1|0.0|1076|dme:Dmel_CG2522|signal recognition particle receptor subunit alpha GO:0030867//rough endoplasmic reticulum membrane GO:0017111//nucleoside-triphosphatase activity;GO:0043021//ribonucleoprotein complex binding;GO:0046914//transition metal ion binding;GO:0032561//guanyl ribonucleotide binding GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0051046//regulation of secretion;GO:0006613//cotranslational protein targeting to membrane 38756 3501.43 281.025 362.925 0.368972961547685 Up 0.586184123629639 CG10077 CG10077, isoform D K12823|1|0.0|795|dme:Dmel_CG10077|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0042623//ATPase activity, coupled;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0032559 - 31922 840.37 66.3 56.82 -0.222610038810409 Down 0.425208030643244 CG9689 CG9689, isoform B - - - - 42291 726.69 537.09 521.51 -0.0424689436017235 Down 0.139578655395588 ATPsyn-d ATP synthase, subunit d, isoform C K02138|1|9e-100|362|dme:Dmel_CG6030|F-type H+-transporting ATPase subunit d [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0015630//microtubule cytoskeleton;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0015630//microtubule cytoskeleton GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 38255 2757.83 25.32 29.15 0.203218478659517 Up 0.364912164839519 CG5687 CG5687, isoform B K03307|1|2e-96|353|ptr:467108|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport 34047 1927.00 5.165 5.095 -0.0196862026992457 Down 0.0542200501915203 CG13793 CG13793 K05040|1|9e-32|138|ptr:471694|solute carrier family 6 (neurotransmitter transporter, L-proline) member 7 GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport 42345 3356.27 20.5 24.395 0.250961573533219 Up 0.403282261260071 CG6184 CG6184, isoform F - - - - 19835935 198.00 0.255 0.01 -4.6724253419715 Down 0.24085325584467 35097 3059.49 42.31 35.005 -0.27343767906508 Down 0.458393871351209 Fas3 fasciclin 3, isoform G K06783|1|2e-06|55.1|ptr:456096|immunoglobulin superfamily, member 4C GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0016337//cell-cell adhesion;GO:0006935//chemotaxis;GO:0019538//protein metabolic process;GO:0007409//axonogenesis;GO:0008039//synaptic target recognition;GO:0003006//developmental process involved in reproduction;GO:0008306//associative learning;GO:0016337//cell-cell adhesion;GO:0006935//chemotaxis;GO:0019538//protein metabolic process;GO:0007409//axonogenesis;GO:0008039//synaptic target recognition;GO:0003006//developmental process involved in reproduction;GO:0008306//associative learning;GO:0016337//cell-cell adhesion;GO:0006935//chemotaxis;GO:0019538//protein metabolic process;GO:0007409//axonogenesis;GO:0008039//synaptic target recognition;GO:0003006//developmental process involved in reproduction;GO:0008306//associative learning;GO:0016337//cell-cell adhesion;GO:0006935//chemotaxis;GO:0019538//protein metabolic process;GO:0007409//axonogenesis;GO:0008039//synaptic target recognition;GO:0003006//developmental process involved in reproduction;GO:0008306//associative learning;GO:0016337//cell-cell adhesion;GO:0006935//chemotaxis;GO:0019538//protein metabolic process;GO:0007409//axonogenesis;GO:0008039//synaptic target recognition;GO:0003006//developmental process involved in reproduction;GO:0008306//associative learning 14462500 618.00 0.125 0.295 1.23878685958712 Up 0.142220314357416 40145 1501.00 67.455 39.01 -0.79008138636561 Down 0.687722889974904 Oat ornithine aminotransferase precursor K00819|1|0.0|862|dme:Dmel_CG8782|ornithine--oxo-acid transaminase [EC:2.6.1.13] GO:0031980 GO:0048037//cofactor binding;GO:0008483//transaminase activity GO:0006520//cellular amino acid metabolic process 19834734 1286.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 318655 1399.00 5.66 0.01 -9.14465824283188 Down 0.848335754854048 CG31274 CG31274 - - GO:0005488//binding - 40392 2439.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 CG7173 CG7173 - - - - 38720 920.00 43.185 39.85 -0.115950565406757 Down 0.270109628846916 CG13298 CG13298 K12833|1|3e-66|251|dya:Dyak_GE20495|pre-mRNA branch site protein p14 GO:0005681//spliceosomal complex GO:0005488//binding GO:0000278//mitotic cell cycle;GO:0000377 318995 1623.00 1.03 1.485 0.527818593617547 Up 0.205422005019152 CG31874 CG31874 K01679|1|0.0|977|dme:Dmel_CG31874|fumarate hydratase, class II [EC:4.2.1.2] GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0044424//intracellular part GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0016836//hydro-lyase activity;GO:0032559 GO:0006810//transport;GO:0043648//dicarboxylic acid metabolic process;GO:0009060//aerobic respiration 47765 2594.00 2.615 3.37 0.365937644934917 Up 0.252047285695417 c(3)G crossover suppressor on 3 of gowen, isoform C K12478|1|4e-27|123|cfa:475424|early endosome antigen 1 GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome - - 39513 4453.06 11.695 11.435 -0.0324354959407551 Down 0.0823537181349888 CG10732 CG10732, isoform D - - - - 33919 647.00 2 1.61 -0.312939311660108 Down 0.173623035266147 CG11043 CG11043 K02265|1|8e-76|282|dme:Dmel_CG11043|cytochrome c oxidase subunit Vb [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0022904//respiratory electron transport chain 43350 3184.15 66.805 52.765 -0.340374804276363 Down 0.538931448949941 CG5508 minotaur, isoform E K00629|1|0.0|1497|dme:Dmel_CG5508|glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups GO:0016044//cellular membrane organization;GO:0006644//phospholipid metabolic process;GO:0016044//cellular membrane organization;GO:0006644//phospholipid metabolic process;GO:0016044//cellular membrane organization;GO:0006644//phospholipid metabolic process 36053 3870.00 19.87 23.06 0.214800640402102 Up 0.360817593448686 CG1371 CG1371 - - GO:0005488//binding;GO:0008238//exopeptidase activity - 42503 1000.00 16.08 15.675 -0.0368019634895272 Down 0.101769911504425 CG17282 bride of doubletime - - - - 43492 1044.00 75.705 75.005 -0.0134018152854312 Down 0.067956676793026 CG7582 CG7582, isoform B - GO:0031224//intrinsic to membrane - GO:0007166//cell surface receptor signaling pathway 40717 1897.00 84.74 53.185 -0.672023715249752 Down 0.669858671245542 Rpn5 regulatory particle non-ATPase 5 K03035|1|0.0|885|dse:Dsec_GM10840|26S proteasome regulatory subunit N5 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 41183 1560.00 6.795 3.195 -1.0886576198204 Down 0.561715757495707 alphaTub85E alpha-Tubulin at 85E K07374|1|0.0|859|dya:Dyak_GE24741|tubulin alpha GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0043623//cellular protein complex assembly;GO:0007017//microtubule-based process 41261 1001.00 6.44 7.19 0.158931082324681 Up 0.201756703209616 CG12818 CG12818 - - - - 42537 1449.00 0.535 0.39 -0.456064767538899 Down 0.114119667150971 bap bagpipe K09995|1|7e-172|603|dme:Dmel_CG7902|homeobox protein Nkx-3.2 GO:0030130//clathrin coat of trans-Golgi network vesicle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0022892;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006901//vesicle coating;GO:0048333//mesodermal cell differentiation;GO:0007517//muscle organ development;GO:0001708//cell fate specification;GO:0015031//protein transport;GO:0048565//digestive tract development;GO:0001505//regulation of neurotransmitter levels 36506 2230.39 43.835 38.61 -0.183108693685911 Down 0.36075155197464 CG6145 CG6145, isoform F K00858|1|0.0|815|dsi:Dsim_GD25753|NAD+ kinase [EC:2.7.1.23] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding - 38504 3753.71 23.735 28.65 0.271519089214835 Up 0.434784044379871 tipE temperature-induced paralytic E, isoform B - GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016247//channel regulator activity;GO:0005272//sodium channel activity;GO:0016247//channel regulator activity;GO:0005272//sodium channel activity GO:0008049//male courtship behavior;GO:0009408//response to heat;GO:0010765//positive regulation of sodium ion transport;GO:0008049//male courtship behavior;GO:0009408//response to heat;GO:0010765//positive regulation of sodium ion transport 37957 1451.00 2.325 0.45 -2.36923380966572 Down 0.508486329414873 CG3880 CG3880 - - - - 3885597 633.00 0.075 0.145 0.951090399519054 Up 0.0885616166952846 CG34005 CG34005, isoform C - - - - 40155 3826.19 80.86 72.435 -0.158739239377883 Down 0.351208558975036 HLH106 helix loop helix protein 106, isoform D K07197|1|4e-119|429|bfo:BRAFLDRAFT_117231|sterol regulatory element-binding transcription factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006633//fatty acid biosynthetic process;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0055088//lipid homeostasis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0055088//lipid homeostasis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0055088//lipid homeostasis;GO:0010557//positive regulation of macromolecule biosynthetic process 4379911 1483.00 0.315 0.415 0.397759507847009 Up 0.0941421212521464 CG17672 CG17672 - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 44703 1457.51 80.895 74.81 -0.112819403679625 Down 0.26888786157707 lolal lola like, isoform H K02174|1|1e-32|140|dme:Dmel_CG11491|broad;K09237|2|7e-32|137|nvi:100122117|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0016458//gene silencing;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0016458//gene silencing;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0016458//gene silencing;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0016458//gene silencing;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0016458//gene silencing;GO:0007431//salivary gland development;GO:0007424//open tracheal system development 49260 2203.00 125.455 131.83 0.0715087453650398 Up 0.196770571919165 Pp1-87B protein phosphatase 1 at 87B K06269|1|4e-179|628|dya:Dyak_GE24518|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0044424//intracellular part GO:0004722//protein serine/threonine phosphatase activity GO:0048731;GO:0006909//phagocytosis;GO:0007626//locomotory behavior;GO:0007052//mitotic spindle organization;GO:0007632//visual behavior;GO:0008306//associative learning;GO:0000070//mitotic sister chromatid segregation;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process 12798088 1040.00 18.015 11.68 -0.625158377546773 Down 0.580900805705983 CG43341 CG43341 - - - - 38711 595.00 0.855 0.59 -0.535209465524057 Down 0.152985074626866 CG13297 CG13297 - - - - 42292 6526.00 34.315 16.31 -1.0730825726317 Down 0.698454629507331 CG6040 CG6040 - - - - 35309 2519.82 31.63 24.405 -0.37411680412371 Down 0.522322018227447 CG10947 CG10947, isoform D - - - - 40682 3187.00 1.92 1.625 -0.240666592805339 Down 0.136870954959715 asl asterless K10352|1|4e-28|127|mmu:17880|myosin heavy chain GO:0005813//centrosome - GO:0031023//microtubule organizing center organization;GO:0007600//sensory perception;GO:0009566//fertilization;GO:0042384//cilium assembly;GO:0003006//developmental process involved in reproduction 40037 1629.54 18.445 10.105 -0.868160467315083 Down 0.635880332849029 Cyp12c1 Cyp12c1, isoform B K00517|1|3e-130|465|dme:Dmel_CG6042| [EC:1.14.-.-];K07436|5|1e-49|197|ecb:100053452|cytochrome P450, family 24, subfamily A (25-hydroxyvitamin D3 24-hydroxylase) GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0009636//response to toxic substance 37725 1200.00 0.01 0.115 3.52356195605701 Up 0.142748646149782 Gr59e gustatory receptor 59e K08471|1|0.0|762|dme:Dmel_CG33151|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 42066 6012.31 25.585 23.095 -0.147717687161005 Down 0.292926958129705 cher cheerio, isoform N K04437|1|0.0|2031|spu:579510|filamin GO:0035324//female germline ring canal;GO:0035324//female germline ring canal GO:0008092//cytoskeletal protein binding;GO:0030246//carbohydrate binding;GO:0008092//cytoskeletal protein binding GO:0007293//germarium-derived egg chamber formation;GO:0007015//actin filament organization;GO:0035171//lamellocyte differentiation;GO:0010259//multicellular organismal aging;GO:0043063//intercellular bridge organization;GO:0033036;GO:0008306//associative learning;GO:0007293//germarium-derived egg chamber formation;GO:0007015//actin filament organization;GO:0035171//lamellocyte differentiation;GO:0010259//multicellular organismal aging;GO:0043063//intercellular bridge organization;GO:0033036;GO:0008306//associative learning 12798226 978.01 3.585 3.055 -0.230800738883175 Down 0.186104873860785 39508 2534.00 8.505 8.365 -0.0239456956250321 Down 0.063333773609827 CG10713 CG10713 - - - - 39588 2784.30 65.595 37.475 -0.807657370967142 Down 0.689241843877955 CG9238 CG9238, isoform C K07189|1|9e-62|238|aga:AgaP_AGAP001520|protein phosphatase 1, regulatory (inhibitor) subunit 3 - GO:0019888//protein phosphatase regulator activity;GO:0019888//protein phosphatase regulator activity - 35717 3116.00 0.05 0.095 0.925999418556223 Up 0.0698718795403513 tor torso, isoform D K12378|1|0.0|1768|dme:Dmel_CG1389|tyrosine-protein kinase receptor torso [EC:2.7.10.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0045165//cell fate commitment;GO:0045137//development of primary sexual characteristics;GO:0010259//multicellular organismal aging;GO:0006796//phosphate-containing compound metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0045927//positive regulation of growth;GO:0016197//endosomal transport;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0048598//embryonic morphogenesis;GO:0007584//response to nutrient;GO:0042254//ribosome biogenesis;GO:0044248//cellular catabolic process;GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0045165//cell fate commitment;GO:0045137//development of primary sexual characteristics;GO:0010259//multicellular organismal aging;GO:0006796//phosphate-containing compound metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0045927//positive regulation of growth;GO:0016197//endosomal transport;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0048598//embryonic morphogenesis;GO:0007584//response to nutrient;GO:0042254//ribosome biogenesis;GO:0044248//cellular catabolic process 36581 1774.00 5.545 5.385 -0.0422411156175024 Down 0.0744617619865275 CG8503 CG8503 K11848|1|1e-179|630|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15];K11426|2|2e-10|67.8|rno:498295|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding GO:0019941//modification-dependent protein catabolic process;GO:0006350 3885620 967.00 0.405 0.315 -0.362570079384708 Down 0.0902126535464272 CG34049 CG34049 - - - - 42123 1383.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 CG14325 CG14325 K09257|1|1e-05|51.6|cin:100180616|nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 - - - 40472 998.00 29.555 17.405 -0.763900406527208 Down 0.648527275128781 CG11425 CG11425 K01080|1|1e-152|538|dme:Dmel_CG11425|phosphatidate phosphatase [EC:3.1.3.4] GO:0044464//cell part GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process 43573 524.46 808.6 822.315 0.024264941982325 Up 0.0939109760929864 RpL32 ribosomal protein L32, isoform D K02912|1|9e-74|276|dvi:Dvir_GJ10385|large subunit ribosomal protein L32e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 2768983 410.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 CG33269 CG33269, isoform B - - - - 39685 1423.85 34.815 32.18 -0.113544697342192 Down 0.248580108308017 CG7427 CG7427, isoform E - - GO:0046872//metal ion binding - 32523 1243.00 22.275 22.93 0.0418109231715093 Up 0.114482895258222 mRpL3 mitochondrial ribosomal protein L3 - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 14462392 381.00 0.46 0.4 -0.20163386116965 Down 0.0688812574296658 42996 807.00 88.41 87.01 -0.0230283427350673 Down 0.0898164047021529 bai baiser K01529|1|5e-07|54.7|mcc:709884| [EC:3.6.1.-] GO:0031224//intrinsic to membrane - GO:0007310//oocyte dorsal/ventral axis specification;GO:0006810//transport 19834930 3099.00 1.165 1.595 0.453226469110589 Up 0.19554880464932 - pre-mod(mdg4)-I - - - - 33244 2549.00 0.09 0.1 0.15200309344505 Up 0.045238409721305 CG2839 CG2839 K06560|1|4e-09|63.9|gga:771876|mannose receptor, C type;K06563|3|4e-09|63.9|mmu:170780|CD209 antigen - - - 46158 2469.00 9.31 9.525 0.0329379248218908 Up 0.0771364416853784 l(3)04053 lethal (3) 04053 - - - - 7354418 1983.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 Ir7f ionotropic receptor 7f - - - - 19836155 1182.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 34494 1263.00 0.04 0.045 0.169925001442312 Up 0.0382380134724607 CG17134 CG17134 K01379|1|9e-123|440|dme:Dmel_CG6508|cathepsin D [EC:3.4.23.5];K06002|1|9e-123|440|dme:Dmel_CG6508|pepsin A [EC:3.4.23.1] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 317880 913.00 1.915 2.23 0.219699317995348 Up 0.140470215295205 CG32141 CG32141 - - - - 42355 1831.00 0.74 0.89 0.266280065337448 Up 0.102232201822745 CG11453 CG11453 K01904|1|8e-49|195|spu:581911|4-coumarate--CoA ligase [EC:6.2.1.12];K01896|5|8e-25|115|gga:426992|medium-chain acyl-CoA synthetase [EC:6.2.1.2] - - - 42399 2188.00 0.075 0.175 1.22239242133645 Up 0.108506141857086 CG10887 CG10887 - - - - 33505 6351.50 17.275 19.5 0.174788413361352 Up 0.302569013340378 Chd1 Chromodomain-helicase-DNA-binding protein 1, isoform C K11367|1|0.0|2877|dme:Dmel_CG3733|chromodomain-helicase-DNA-binding protein 1 [EC:3.6.1.-] GO:0044427//chromosomal part;GO:0005700//polytene chromosome GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0000166//nucleotide binding GO:0007472//wing disc morphogenesis;GO:0007292//female gamete generation;GO:0043486//histone exchange;GO:0010467//gene expression 32854 3357.97 12.485 14.65 0.230704843381398 Up 0.338990886276582 CG6659 CG6659, isoform B K13145|1|2e-07|58.5|ptr:464291|integrator complex subunit 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 38815 653.00 27.89 31.03 0.153915762500407 Up 0.305904107779686 Srp19 signal recognition particle protein 19 K03105|1|2e-80|297|dme:Dmel_CG4457|signal recognition particle subunit SRP19 GO:0048500//signal recognition particle GO:0003723//RNA binding GO:0006613//cotranslational protein targeting to membrane 33090 1338.63 0.82 1.585 0.950787025521323 Up 0.301215163122441 CG1503 CG1503, isoform B K08597|1|6e-12|72.0|nve:NEMVE_v1g238848|sentrin-specific protease 8 [EC:3.4.22.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 10178957 422.00 8.74 2.19 -1.99670240989943 Down 0.677882710342095 CG42751 CG42751 - - - - 31359 1039.26 121.805 86.045 -0.501410089901418 Down 0.63310659093911 cib ciboulot, isoform E - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding GO:0002165//instar larval or pupal development;GO:0006996//organelle organization;GO:0002165//instar larval or pupal development;GO:0006996//organelle organization;GO:0002165//instar larval or pupal development;GO:0006996//organelle organization 39238 2221.87 12.945 16.565 0.355743238180903 Up 0.457667415136706 Mocs1 molybdenum cofactor synthesis 1 ortholog, isoform C K03637|1|2e-69|264|dya:Dyak_GE21784|molybdenum cofactor biosynthesis protein C GO:0043234//protein complex;GO:0043234//protein complex GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding GO:0009108//coenzyme biosynthetic process;GO:0009108//coenzyme biosynthetic process 5740714 848.00 201.515 61.745 -1.70649301174118 Down 0.777043983621714 CG34327 CG34327 - - - - 318574 2073.00 1.47 1.41 -0.0601209924375709 Down 0.0576872275789196 CG31055 CG31055, isoform C - - - - 31038 602.00 22.85 22.565 -0.018107386732945 Down 0.0758156122044644 MED22 mediator complex subunit 22 - - - - 37727 1607.02 74.195 41.98 -0.821619800293411 Down 0.693897767798177 wmd wing morphogenesis defect, isoform B K13137|1|0.0|653|dse:Dsec_GM15531|serine-threonine kinase receptor-associated protein GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0004871//signal transducer activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0004871//signal transducer activity;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis 19835712 512.00 0.885 0.52 -0.767165831941905 Down 0.196275260863822 40117 1674.66 12.88 12.045 -0.0966981998761463 Down 0.176892088231409 CG9449 CG9449, isoform K K01078|1|7e-134|477|dme:Dmel_CG9452|acid phosphatase [EC:3.1.3.2] - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity GO:0006909//phagocytosis;GO:0006909//phagocytosis 44498 1055.00 10 10.825 0.114367024952 Up 0.182472592788271 Surf1 surfeit 1 - - GO:0051184 GO:0043623//cellular protein complex assembly;GO:0002164//larval development;GO:0007610//behavior;GO:0009416//response to light stimulus 19835545 451.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 32552 7386.29 39.945 48.92 0.292409474595616 Up 0.485041606128649 CG8909 CG8909, isoform D K03068|1|0.0|915|cfa:477692|low density lipoprotein receptor-related protein 5/6 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding - 34468 648.59 57.28 47.485 -0.270559639016314 Down 0.471569145423326 CG7299 CG7299, isoform C - - - - 31326 1777.11 4.075 4.23 0.0538576040015098 Up 0.0768722757891956 CG2875 CG2875, isoform C - - - - 38813 1875.00 32.715 23 -0.508318409530169 Down 0.590047549861313 CG8596 CG8596, isoform C K12307|1|0.0|1045|dme:Dmel_CG8596|MFS transporter, ceroid-lipofuscinosis neuronal protein 7 - - GO:0006810//transport 39205 334.00 42.085 65.405 0.636094811956781 Up 0.657244749702813 CG18628 CG18628 - - - - 40737 823.00 0.43 1.85 2.10511670581421 Up 0.448223484348171 Obp83a Odorant-binding protein 83a, isoform C - GO:0044421//extracellular region part GO:0008144//drug binding;GO:0005549//odorant binding GO:0051234//establishment of localization 3772323 141.00 0.445 0.01 -5.4757334309664 Down 0.335292563730022 12798381 608.00 0.595 0.89 0.580915667658454 Up 0.168042530709285 CG43183 CG43183 - - - - 31274 1106.00 0.285 0.045 -2.66296501272243 Down 0.192048606524898 CG14417 CG14417 - - - - 36643 4061.61 60.57 66.515 0.135076312461342 Up 0.315315017831198 Spred Sprouty-related protein with EVH-1 domain, isoform C K04703|1|0.0|864|dan:Dana_GF13513|sprouty-related, EVH1 domain containing GO:0044464//cell part - GO:0032501//multicellular organismal process;GO:0007165//signal transduction 36858 2200.00 18.25 11.295 -0.692212193261657 Down 0.597279091269317 CG8303 CG8303, isoform D K13356|1|5e-69|262|ame:551233|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 37371 462.00 1.79 0.865 -1.04918754962753 Down 0.335292563730022 CG15649 CG15649, isoform B - - - - 318904 1710.00 0.12 0.07 -0.777607578663552 Down 0.0762779025227843 CG31702 CG31702 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0006464//cellular protein modification process 37635 888.00 38.09 37.265 -0.03159102824189 Down 0.104345528992207 CG3501 CG3501 - GO:0015630//microtubule cytoskeleton - - 42267 2879.69 119.11 134.8 0.178525955317935 Up 0.39040417382116 Xrp1 Xrp1, isoform G - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0007635//chemosensory behavior;GO:0006996//organelle organization;GO:0008283//cell proliferation;GO:0007635//chemosensory behavior;GO:0006996//organelle organization;GO:0008283//cell proliferation;GO:0007635//chemosensory behavior;GO:0006996//organelle organization;GO:0008283//cell proliferation;GO:0007635//chemosensory behavior;GO:0006996//organelle organization;GO:0008283//cell proliferation;GO:0007635//chemosensory behavior;GO:0006996//organelle organization;GO:0008283//cell proliferation 318840 933.00 0.34 0.325 -0.0650950282218847 Down 0.042365605600317 CG33062 CG33062, isoform B - - - - 34348 4324.66 0.085 2.05 4.59201725825511 Up 0.586877559107119 CG4839 CG4839, isoform B K07376|1|0.0|1875|dme:Dmel_CG4839|protein kinase, cGMP-dependent [EC:2.7.11.12] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 317976 1211.00 0.385 0.32 -0.266786540694901 Down 0.0726126007132479 CG32319 CG32319 K00670|1|3e-42|171|isc:IscW_ISCW015138|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0016407//acetyltransferase activity GO:0043543 40979 5490.25 2.44 1.495 -0.706735663364781 Down 0.315182934883107 CG9626 CG9626, isoform D - - - - 35177 4323.83 10.33 12.19 0.238857871755153 Up 0.32703737947431 CG10492 CG10492, isoform B - - GO:0005488//binding;GO:0005488//binding - 19835724 829.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 40366 2185.00 0.91 1.125 0.305986551018341 Up 0.125478800686831 CG32437 CG32437 - - - - 43071 4288.00 0.365 0.875 1.26138655295231 Up 0.258156122044644 rha rha K10352|1|4e-07|58.2|dre:561431|myosin heavy chain;K11135|2|9e-07|57.0|dsi:Dsim_GD25264|Pin2-interacting protein X1;K05763|3|1e-06|56.2|mcc:711712|moesin - - - 10178878 1114.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 39494 223.00 19.19 23.515 0.293226620662601 Up 0.439506009774138 Acp70A Sex peptide - - GO:0005102//receptor binding GO:0046662//regulation of oviposition;GO:0007292//female gamete generation;GO:0045297//post-mating behavior;GO:0006718//juvenile hormone biosynthetic process;GO:0007621//negative regulation of female receptivity;GO:0007631//feeding behavior 32409 606.00 0.485 0.755 0.638491897137951 Up 0.15998547087571 CG14410 CG14410 - - - - 31978 1234.00 0.16 0.075 -1.09310940439148 Down 0.0978734645357284 CG2887 CG2887 K09507|1|3e-69|262|tca:661242|DnaJ homolog subfamily B member 1;K09510|2|5e-69|261|cqu:CpipJ_CPIJ018848|DnaJ homolog subfamily B member 4 GO:0015630//microtubule cytoskeleton GO:0005515//protein binding GO:0044267//cellular protein metabolic process 2768659 661.00 4.38 5 0.190997225060914 Up 0.192874124950469 CG33293 CG33293 - - - - 48903 1322.00 15.025 17.44 0.215035049178378 Up 0.344109100515124 l(3)73Ah lethal (3) 73Ah, isoform B K11488|1|9e-131|467|dvi:Dvir_GJ12822|polycomb group RING finger protein 3 - GO:0046914//transition metal ion binding - 32897 734.00 48.085 33.26 -0.53179875030565 Down 0.616596222427685 Obp18a Odorant-binding protein 18a - - GO:0005488//binding GO:0051234//establishment of localization 33266 745.10 0.445 0.495 0.153623189113212 Up 0.0638290846651697 CG13949 CG13949, isoform C - - - - 246412 3082.00 0.04 0.135 1.75488750216347 Up 0.112336547351737 CG30043 CG30043 - - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 37284 2572.00 1.955 0.585 -1.74066007772395 Down 0.431944260995905 Efhc1.2 EFHC1 homologue 2 - - - - 14462567 953.00 1.7 0.835 -1.02568664366365 Down 0.32588165367851 318977 707.00 12.835 15.625 0.283772893861393 Up 0.393442081627262 mRpS23 mitochondrial ribosomal protein S23 K03574|1|2e-16|85.5|ame:410765|7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] - GO:0005198//structural molecule activity - 43067 1463.00 28.585 20.55 -0.476119896364708 Down 0.5683529256373 CHKov1 CHKov1 - - GO:0003676//nucleic acid binding;GO:0034061 - 36084 3810.65 57.815 82.53 0.513474794395254 Up 0.628219521859728 CAP CAP, isoform Y K06086|1|2e-56|222|ssc:100153151|sorbin and SH3 domain containing 1 GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559;GO:0032559 GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation;GO:0007059//chromosome segregation 5740872 654.00 0.01 0.14 3.8073549220576 Up 0.163848897107383 CG40551 CG40551 - - GO:0046872//metal ion binding - 39196 820.00 1.24 1.545 0.317266717517499 Up 0.153348302734117 CG32061 CG32061 - - - - 33649 1863.00 7.745 8.175 0.0779534915958764 Up 0.12696473385286 Elp3 elongator complex protein 3 K07739|1|0.0|1118|dme:Dmel_CG15433|elongator complex protein 3 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0043169//cation binding;GO:0004468//lysine N-acetyltransferase activity;GO:0051540;GO:0019887//protein kinase regulator activity GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0043954//cellular component maintenance 5740205 796.00 3.795 4.055 0.0956020288018066 Up 0.106425835424647 CG34261 CG34261 - - - - 39906 567.00 0.29 1.47 2.34169134970879 Up 0.42342491084401 a10 antennal protein 10 K04352|1|4e-22|103|dan:Dana_GF20186|Ras GTPase-activating protein 1;K11321|2|6e-12|70.1|tca:661106|bromodomain-containing protein 8 - GO:0005549//odorant binding - 31444 952.00 0.5 0.455 -0.136061549576028 Down 0.0587769119006736 dhd deadhead, isoform B K03671|1|7e-22|103|aga:AgaP_AGAP009584|thioredoxin 1 GO:0043231//intracellular membrane-bounded organelle GO:0016667//oxidoreductase activity, acting on a sulfur group of donors GO:0051234//establishment of localization;GO:0033554//cellular response to stress;GO:0007126//meiosis;GO:0007275//multicellular organismal development;GO:0019725//cellular homeostasis;GO:0006091//generation of precursor metabolites and energy 251610 644.00 11.665 12.58 0.10894561489509 Up 0.189902258618412 CG31142 CG31142 - - - - 39084 1455.00 5 10.6 1.08406426478847 Up 0.61643111874257 CG3982 CG3982 - - - - 46719 4000.00 2.605 1.915 -0.443938980353551 Down 0.248547087570995 dlt discs lost - GO:0044424//intracellular part - GO:0007444//imaginal disc development;GO:0008283//cell proliferation;GO:0007635//chemosensory behavior;GO:0051320//S phase;GO:0002009//morphogenesis of an epithelium 34359 1035.39 93.28 56.645 -0.719619172184734 Down 0.683562277110025 Pros35 proteasome alpha6 subunit, isoform B K02725|1|4e-143|507|dme:Dmel_CG4904|20S proteasome subunit alpha 6 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process 41739 1843.00 0.715 0.76 0.0880561766651961 Up 0.0575221238938053 CG3259 CG3259 - - - - 19834723 414.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 41629 2173.00 55.48 35.645 -0.638268066703588 Down 0.651168934090609 CG8630 CG8630 K00507|1|0.0|817|dsi:Dsim_GD18893|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] - - - 33097 843.00 0.19 0.57 1.58496250072116 Up 0.231475366530181 CG1724 CG1724 K10836|1|7e-77|286|dme:Dmel_CG1724|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic to membrane GO:0008565//protein transporter activity GO:0015031//protein transport 34540 3287.06 6.115 6.14 0.00588615684279288 Up 0.0453704926693964 CG4705 CG4705, isoform D K10752|1|1e-11|72.4|hmg:100199460|histone-binding protein RBBP4 - - - 42749 2869.00 15.905 15.045 -0.0801962652061765 Down 0.162891295733721 EloA elongin A, isoform B K03145|1|2e-06|55.1|ame:410020|transcription elongation factor S-II GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0008135//translation factor activity, nucleic acid binding;GO:0003711//transcription elongation regulator activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003711//transcription elongation regulator activity GO:0006354//DNA-dependent transcription, elongation;GO:0010468//regulation of gene expression;GO:0006354//DNA-dependent transcription, elongation;GO:0010468//regulation of gene expression 50107 437.13 12.525 11.695 -0.0989187417301431 Down 0.176892088231409 CG4186 CG4186, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0015002//heme-copper terminal oxidase activity - 42723 1469.30 6.05 3.98 -0.604166711618308 Down 0.429830933826443 CG17119 CG17119, isoform C K12386|1|0.0|652|dme:Dmel_CG17119|cystinosin GO:0005764//lysosome;GO:0005764//lysosome GO:0005488//binding;GO:0005275//amine transmembrane transporter activity;GO:0005488//binding;GO:0005275//amine transmembrane transporter activity GO:0000101//sulfur amino acid transport;GO:0023060;GO:0000101//sulfur amino acid transport;GO:0023060 43359 1701.00 86.85 41.06 -1.08079222148915 Down 0.727281732928279 betaTub97EF beta-Tubulin at 97EF, isoform C K07375|1|0.0|1005|dse:Dsec_GM16302|tubulin beta GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0043623//cellular protein complex assembly;GO:0007017//microtubule-based process;GO:0016477//cell migration;GO:0043623//cellular protein complex assembly;GO:0030154//cell differentiation;GO:0007017//microtubule-based process 318103 699.00 11.99 12.12 0.0155580400587272 Up 0.0624091929731872 CG32590 CG32590 - - - - 42947 1258.02 38.035 41.44 0.123696397975247 Up 0.270869105798441 Ast allatostatin A, isoform B - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation;GO:0002164//larval development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 2768852 5342.07 102.99 103.315 0.00454546691701501 Up 0.0468564258354246 par-1 par-1, isoform X K08798|1|0.0|1568|der:Dere_GG21978|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466;GO:0006959//humoral immune response;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0051235;GO:0006464//cellular protein modification process;GO:0035466 32837 1132.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 Rad51D Rad51D K10879|1|3e-08|59.7|gga:420438|DNA-repair protein XRCC2 - GO:0042623//ATPase activity, coupled GO:0006259//DNA metabolic process 33796 2146.39 4.05 7.075 0.804808239947258 Up 0.512613921542729 Hsp60C Hsp60C, isoform C K04077|1|0.0|1048|dse:Dsec_GM18564|chaperonin GroEL GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0007293//germarium-derived egg chamber formation;GO:0006457//protein folding;GO:0060541//respiratory system development;GO:0006605//protein targeting;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0007293//germarium-derived egg chamber formation;GO:0006457//protein folding;GO:0060541//respiratory system development;GO:0006605//protein targeting;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0007293//germarium-derived egg chamber formation;GO:0006457//protein folding;GO:0060541//respiratory system development;GO:0006605//protein targeting;GO:0048232//male gamete generation;GO:0006950//response to stress 37977 3322.00 4.095 4.85 0.244121295433481 Up 0.224243825122177 CG16896 CG16896 K11515|1|6e-07|57.0|xla:398822|inner centromere protein;K10392|3|8e-07|56.6|bfo:BRAFLDRAFT_227179|kinesin family member 1/13/14 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 37051 773.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG5084 CG5084, isoform B - - - - 35934 1196.00 14.875 14.875 0 - 0.0382380134724607 Prp38 pre-mRNA processing factor 38 K12849|1|2e-124|445|dme:Dmel_CG30342|pre-mRNA-splicing factor 38A GO:0005681//spliceosomal complex GO:0005488//binding GO:0000377;GO:0000086//G2/M transition of mitotic cell cycle 37376 3291.00 0.035 0.055 0.652076696579693 Up 0.0550785893541144 CG3216 CG3216, isoform D K12323|1|0.0|2302|dse:Dsec_GM15763|atrial natriuretic peptide receptor A [EC:4.6.1.2] - - - 37739 1052.26 277.525 278.99 0.00759567349339092 Up 0.0694756306960771 CG4019 CG4019, isoform F K09884|1|3e-133|474|dme:Dmel_CG4019|aquaporin rerated protein, invertebrate GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0022803;GO:0022803;GO:0022803;GO:0022803 GO:0003008;GO:0006810//transport;GO:0003008;GO:0006810//transport;GO:0003008;GO:0006810//transport;GO:0003008;GO:0006810//transport 326116 2234.92 113.98 138.81 0.284330806944861 Up 0.50475498613129 tau tau, isoform M K04380|1|5e-135|481|dme:Dmel_CG31057|microtubule-associated protein tau GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding GO:0007019//microtubule depolymerization 318778 1158.00 0.18 0.865 2.26470322619441 Up 0.325485404834236 Or82a odorant receptor 82a K08471|1|0.0|709|dme:Dmel_CG31519|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 35267 6999.05 10.465 10.135 -0.0462262227888103 Down 0.100944393078854 CdGAPr Cd GTPase activating protein-related, isoform D K08878|1|1e-25|120|cin:100176232|breakpoint cluster region protein [EC:2.7.11.1];K05732|4|1e-22|110|xla:414634|glucocorticoid receptor DNA-binding factor 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - GO:0007411//axon guidance;GO:0023060;GO:0007411//axon guidance;GO:0023060;GO:0007411//axon guidance;GO:0023060 36749 1057.00 24.755 20.865 -0.246635028698765 Down 0.403282261260071 CG8297 CG8297 - - - GO:0019725//cellular homeostasis 39351 1502.00 1.8 1.89 0.070389327891398 Up 0.0656122044644036 Rpt4R regulatory particle triple-A ATPase 4-related, isoform B K03064|1|0.0|787|dme:Dmel_CG7257|26S proteasome regulatory subunit T4 GO:0043234//protein complex;GO:0044424//intracellular part GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0033554//cellular response to stress 117486 1173.00 0.04 0.165 2.04439411935845 Up 0.1267335886937 Gr36c gustatory receptor 36c K08471|1|8e-91|333|dme:Dmel_CG31744|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 37690 1107.00 1.115 1.51 0.437504839404774 Up 0.185510500594373 Prosbeta5R proteasome beta5 subunit-related 1 K02737|1|2e-180|631|dme:Dmel_CG9868|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0006508//proteolysis 41310 1791.00 15.795 14.505 -0.122917641548876 Down 0.221899352793554 Tsp86D tetraspanin 86D, isoform C K10303|1|1e-50|201|dre:324950|F-box protein 23 GO:0031224//intrinsic to membrane - GO:0048731;GO:0006909//phagocytosis 34036 1821.00 95.745 60.13 -0.671112189980874 Down 0.67250033020737 Cyp4d21 Cyp4d21 K00517|1|0.0|970|dme:Dmel_CG6730| [EC:1.14.-.-] GO:0044424//intracellular part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0022414//reproductive process 31095 3382.00 9.315 11.805 0.341770367287005 Up 0.40721172896579 CG14786 CG14786 - - - - 37480 905.62 306.015 307.7 0.00792207214167411 Up 0.0698058380663056 HmgZ HMG protein Z, isoform D K09272|1|2e-26|119|tca:661780|structure-specific recognition protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding GO:0051276//chromosome organization;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0051276//chromosome organization;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 44059 482.00 759.795 682.2 -0.155415463107239 Down 0.373233390569278 RpL30 ribosomal protein L30, isoform E K02908|1|9e-57|218|dsi:Dsim_GD21790|large subunit ribosomal protein L30e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0007399//nervous system development;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0007399//nervous system development;GO:0010467//gene expression 43367 1066.00 4.49 8.505 0.921595790922238 Up 0.563168669924713 Mst98Cb Male-specific RNA 98Cb - - - - 32015 2424.00 0.745 1.08 0.535718981701307 Up 0.177783648131026 feo fascetto - GO:0044430//cytoskeletal part - GO:0022402//cell cycle process;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0032506 37296 2708.00 5.3 6.945 0.389982334530831 Up 0.362567692510897 CG9143 CG9143 K01529|1|7e-55|216|dpo:Dpse_GA21647| [EC:3.6.1.-] - - - 37027 1078.00 0.255 0.135 -0.917537839808027 Down 0.113492273147537 HLH54F HLH54F K09072|1|2e-07|57.0|xtr:100124790|musculin (activated B-cell factor-1) - - - 35806 1258.00 0.95 1.32 0.474538511027506 Up 0.181977281732928 CG30371 CG30371 K01324|1|4e-31|135|hsa:3818|plasma kallikrein [EC:3.4.21.34];K09641|2|6e-30|131|mcc:711510|transmembrane protease, serine 11D [EC:3.4.21.-];K01323|5|9e-29|127|ptr:461643|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40179 1492.59 198.11 228.915 0.208510295761368 Up 0.436369039756967 RhoGDI RhoGDI, isoform B K12462|1|4e-103|375|dsi:Dsim_GD14840|Rho GDP-dissociation inhibitor GO:0044424//intracellular part GO:0005092//GDP-dissociation inhibitor activity - 34486 2581.00 34.69 42.61 0.296672210891837 Up 0.487650244353454 CG6495 CG6495 K06233|1|2e-06|55.1|ecb:100062836|low density lipoprotein-related protein 2 - - - 12798078 570.00 0.01 0.24 4.58496250072116 Up 0.234975564654603 CG43441 CG43441 - - - - 41195 1433.61 65.78 57.735 -0.188202836303407 Down 0.387993660018492 CG8481 CG8481, isoform B - - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 36788 5506.00 11.14 12.015 0.109087415789835 Up 0.186666226390173 lbk lambik K13023|1|6e-25|117|mcc:707574|carboxypeptidase N regulatory subunit - GO:0005488//binding GO:0009451//RNA modification 42206 4933.34 10.42 13.93 0.418839980322745 Up 0.47219653942676 CG15803 CG15803, isoform C K06095|1|1e-41|172|tgu:100230229|multiple PDZ domain protein - - - 40873 1894.00 2.03 2.33 0.198850227469104 Up 0.135186897371549 CG10050 CG10050 - - GO:0008144//drug binding;GO:0005549//odorant binding - 12798426 2190.63 4.27 2.195 -0.960015130085132 Down 0.464304583278299 40442 4506.07 0.365 0.245 -0.575114714764809 Down 0.106161669528464 CS-2 chitin synthase 2, isoform D K00698|1|0.0|2727|dme:Dmel_CG7464|chitin synthase [EC:2.4.1.16] - GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity - 45875 3352.52 133.22 136.265 0.0326043629341915 Up 0.113591335358605 Hex-A hexokinase A, isoform C K00844|1|0.0|1003|dme:Dmel_CG3001|hexokinase [EC:2.7.1.1] - GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559 GO:0040011//locomotion;GO:0006007//glucose catabolic process;GO:0040011//locomotion;GO:0006007//glucose catabolic process 37534 1664.00 31.99 30.285 -0.0790175810630444 Down 0.190793818518029 CG11275 CG11275 K10481|1|2e-10|67.8|hmg:100203646|BTB/POZ domain-containing protein 9 - GO:0005488//binding - 36279 2316.00 13.4 12.26 -0.128274021654353 Down 0.221205917316075 CG33145 CG33145, isoform B K07819|1|0.0|462|dme:Dmel_CG33145|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 38492 1127.00 8.21 9.04 0.138940550637383 Up 0.201525558050456 RfC4 replication factor C subunit 4 K10755|1|0.0|636|dme:Dmel_CG14999|replication factor C subunit 2/4 GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton;GO:0005657//replication fork GO:0032559;GO:0003677//DNA binding;GO:0003678//DNA helicase activity GO:0006261//DNA-dependent DNA replication;GO:0007143//female meiosis;GO:0009207;GO:0007165//signal transduction;GO:0000070//mitotic sister chromatid segregation;GO:0031570 39400 2169.00 7.36 7.07 -0.057995551247614 Down 0.100184916127328 CG32100 CG32100 - - - - 41774 6745.00 0.25 0.165 -0.599462070416271 Down 0.0941091005151235 Cad88C cadherin 88C K06813|1|2e-170|600|dre:407978|cadherin 23 - - - 32042 2036.15 12.95 15.335 0.243876068693103 Up 0.354048342359001 CG2061 CG2061, isoform D - - - GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway 35499 2638.81 49.045 44.705 -0.133669867565716 Down 0.293290186236957 CG11665 CG11665, isoform B K08189|1|2e-35|151|mcc:713985|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13;K08186|5|1e-34|148|ecb:100062703|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 9 - - GO:0006810//transport 40590 3946.40 13 13.075 0.00829932321848684 Up 0.0513802668075551 CG44098 CG44098, isoform E K08202|1|2e-34|148|bfo:BRAFLDRAFT_67944|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5;K08204|5|3e-29|131|mdo:100011322|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 7 - GO:0005488//binding GO:0006810//transport 35865 3108.54 133.98 158.57 0.243102195099792 Up 0.465460309074099 stmA stambha A, isoform D - GO:0005624//membrane fraction;GO:0005624//membrane fraction;GO:0005624//membrane fraction - GO:0006887//exocytosis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0006897//endocytosis;GO:0051301//cell division;GO:0006887//exocytosis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0006897//endocytosis;GO:0051301//cell division;GO:0006887//exocytosis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0006897//endocytosis;GO:0051301//cell division 36394 1763.00 2.015 1.815 -0.150810290532217 Down 0.105204068154801 CG8646 CG8646 K01135|1|0.0|1175|dme:Dmel_CG8646|arylsulfatase B [EC:3.1.6.12];K12375|4|6e-96|351|mmu:545260|arylsulfatase I/J [EC:3.1.6.-] - GO:0016788//hydrolase activity, acting on ester bonds - 32781 1710.00 2.045 1.515 -0.432783049468798 Down 0.21651697265883 CG12672 CG12672 - - - - 41610 1557.00 45.935 21.57 -1.09056765218565 Down 0.712125214634791 CG7966 CG7966 K01090|1|3e-32|139|cel:F42G8.8|protein phosphatase [EC:3.1.3.16] - - - 42778 3272.88 18.93 18.785 -0.0110932950619342 Down 0.0576542068418967 beat-IV beat-IV, isoform B - GO:0044464//cell part - - 38173 3251.63 75.785 92.175 0.282463184916116 Up 0.496598864086646 pUf68 poly U binding factor 68kD, isoform J K12838|1|2e-176|577|dya:Dyak_GE20955|poly(U)-binding-splicing factor PUF60 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development;GO:0007049//cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0007281//germ cell development 41777 1185.00 45.21 24.525 -0.882388781212379 Down 0.68732664113063 CG3505 CG3505 K01362|1|3e-67|255|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|3|3e-51|202|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - - - 41873 2802.85 28.7 38.46 0.422308025776847 Up 0.561088363492273 CG34404 CG34404, isoform E K08282|1|1e-09|65.5|ecb:100050621|non-specific serine/threonine protein kinase [EC:2.7.11.1] - - - 36168 2376.02 6.485 5.4 -0.264147167200869 Down 0.270571919165236 CG13229 CG13229, isoform C K04282|1|1e-11|71.2|xla:373632|thyrotropin-releasing hormone receptor;K08428|2|3e-10|66.6|ecb:100049812|G protein-coupled receptor 139 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway 38643 1946.79 258.9 136.71 -0.921276188843078 Down 0.725432571654999 DnaJ-1 DnaJ-like-1, isoform B K09510|1|0.0|650|dme:Dmel_CG10578|DnaJ homolog subfamily B member 4 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 34013 1898.00 31.31 30.46 -0.0397075666513777 Down 0.11966715097081 CG5149 CG5149 - GO:0043296//apical junction complex - - 34662 2743.00 0.115 0.14 0.283792966000592 Up 0.0592061814819707 Oatp33Eb organic anion transporting polypeptide 33Eb - GO:0044464//cell part GO:0008509//anion transmembrane transporter activity GO:0006820//anion transport 43651 5803.00 14.97 15.205 0.0224715949723811 Up 0.0722823933430194 wts warts K08791|1|0.0|1460|dme:Dmel_CG12072|LATS, large tumor suppressor [EC:2.7.11.1] - GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0016564//transcription repressor activity GO:0007444//imaginal disc development;GO:0045926//negative regulation of growth;GO:0008283//cell proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0043704//photoreceptor cell fate specification;GO:0001654//eye development;GO:0022402//cell cycle process;GO:0006464//cellular protein modification process;GO:0060446//branching involved in open tracheal system development;GO:0009314//response to radiation;GO:0046620//regulation of organ growth 31083 2460.00 4.225 3.845 -0.13596774320772 Down 0.141460837405891 CG11417 CG11417 - - - - 41007 1173.00 0.04 0.08 1 Up 0.0725795799762251 Or85b odorant receptor 85b K08471|1|0.0|757|dme:Dmel_CG11735|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 31031 6999.90 20.605 19.85 -0.0538554562501791 Down 0.128945978074231 CG43867 CG43867, isoform L K12559|1|2e-14|82.8|nve:NEMVE_v1g162932|myosin X;K10359|4|2e-11|72.8|spu:373219|myosin VII - - - 32517 4350.00 5.155 6.125 0.248737416521825 Up 0.253731343283582 CG8944 CG8944 K09228|1|1e-25|119|mmu:212281|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 14462678 476.00 0.265 0.1 -1.40599235967584 Down 0.140173028662 CG43851 CG43851 - - - - 41238 1413.31 74.89 62.395 -0.263342665772658 Down 0.469984150046229 CG3940 CG3940, isoform C K01672|1|2e-177|622|dme:Dmel_CG3940|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 32694 2433.00 25.27 24.75 -0.0299971390904407 Down 0.0974111742174085 CG16700 CG16700 K13576|1|6e-09|63.2|xla:444254|sodium-coupled neutral amino acid transporter 3 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity GO:0006865//amino acid transport 34452 2144.00 15.365 12.59 -0.287369483873946 Down 0.39816404702153 CG18302 CG18302 K01046|1|7e-73|275|dpo:Dpse_GA20265|triacylglycerol lipase [EC:3.1.1.3];K01066|3|3e-70|266|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|5|1e-54|214|ecb:100071626|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - - GO:0044238//primary metabolic process 32442 7634.44 31.155 41.08 0.398972464752391 Up 0.553559635451063 rab3-GEF Rab3 GDP-GTP exchange factor, isoform H - GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle GO:0005488//binding;GO:0016746//transferase activity, transferring acyl groups;GO:0005488//binding GO:0006810//transport;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0000165//MAPK cascade;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0000165//MAPK cascade;GO:0001505//regulation of neurotransmitter levels 40660 4018.01 12.19 14.07 0.20692420261632 Up 0.313796063928147 ksr kinase suppressor of ras, isoform D K02644|1|5e-48|193|dpo:Dpse_GA15481|pole hole;K04366|3|9e-48|192|mmu:110157|RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] - GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0032559 GO:0007472//wing disc morphogenesis;GO:0007264//small GTPase mediated signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007424//open tracheal system development;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process 35519 7712.00 0.09 0.105 0.222392421336448 Up 0.0521727644961036 CG43366 CG43366 K13963|1|6e-21|104|dre:568898|serpin B - GO:0004866//endopeptidase inhibitor activity - 41723 3292.00 1.905 2.89 0.601278495007357 Up 0.310493990225862 CG14355 CG14355 - - - - 36028 3398.58 48.355 52.255 0.111904012672864 Up 0.260302469951129 CG1513 CG1513, isoform C K08283|1|7e-10|67.0|bfo:BRAFLDRAFT_118505|Goodpasture-antigen-binding protein kinase [EC:2.7.11.9] - - GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process 33642 2920.00 223.505 177.73 -0.330619883948762 Down 0.555805045568617 Tps1 Trehalose-6-phosphate synthase 1 K00697|1|0.0|1621|dme:Dmel_CG4104|alpha,alpha-trehalose-phosphate synthase (UDP-forming) [EC:2.4.1.15] GO:0044444//cytoplasmic part GO:0035251//UDP-glucosyltransferase activity GO:0005991//trehalose metabolic process 31422 2723.00 10.85 11.355 0.0656326633750464 Up 0.129804517236825 CG4041 CG4041 K04416|1|2e-12|74.7|nve:NEMVE_v1g120549|mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25];K08824|2|9e-12|72.8|phu:Phum_PHUM420100|cyclin-dependent kinase-like [EC:2.7.11.22];K02091|3|1e-11|72.4|nve:NEMVE_v1g244885|cyclin-dependent kinase 6 [EC:2.7.11.22];K07198|4|3e-11|71.2|bfo:BRAFLDRAFT_239705|5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11];K08857|5|3e-11|70.9|cin:100186341|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0016301//kinase activity;GO:0032559 GO:0032318//regulation of Ras GTPase activity;GO:0006464//cellular protein modification process 31016 980.46 181.16 185.395 0.0333378913048781 Up 0.114515915995245 skpA skpA, isoform I K03094|1|8e-91|333|dsi:Dsim_GD16521|S-phase kinase-associated protein 1 - - - 38614 858.00 10.02 8.775 -0.191411478003286 Down 0.263637564390437 membrin membrin K08496|1|1e-105|382|dme:Dmel_CG4780|golgi SNAP receptor complex member 2 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0006909//phagocytosis;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 42393 1824.00 8.385 8.095 -0.0507797032617802 Down 0.0960903447364945 CG4936 CG4936 K09228|1|6e-38|159|mmu:235907|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 39004 5619.67 19.85 24.965 0.330767899299772 Up 0.477512878087439 Fhos formin homology 2 domain containing ortholog, isoform J K05740|1|2e-23|112|mdo:100027799|diaphanous 1;K05745|4|4e-21|105|bta:525628|diaphanous 3 - GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization 33389 3910.00 6.03 6.725 0.157376265543902 Up 0.194128912957337 CG7261 CG7261 K12864|1|1e-127|458|bmy:Bm1_49395|beta-catenin-like protein 1 - GO:0005488//binding - 39516 5097.15 2.58 3.105 0.267222202797227 Up 0.191817461365738 CG10738 CG10738, isoform F K12323|1|0.0|1297|phu:Phum_PHUM100000|atrial natriuretic peptide receptor A [EC:4.6.1.2];K01769|2|0.0|862|tca:657050|guanylate cyclase, other [EC:4.6.1.2] GO:0016020//membrane;GO:0016020//membrane GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0001653//peptide receptor activity;GO:0016301//kinase activity;GO:0032559;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0001653//peptide receptor activity;GO:0016301//kinase activity;GO:0032559 GO:0023060;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023060;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0006464//cellular protein modification process 12798391 407.92 1.9 3.68 0.953706347726065 Up 0.43894465724475 CG43172 CG43172, isoform B - - - - 326167 2264.00 0.49 0.64 0.385290155884792 Up 0.111610091137234 CG31860 zinc transporter 33D, isoform C K03295|1|3e-38|121|mmu:22785|cation efflux system protein, CDF family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0015075//ion transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0006811//ion transport;GO:0023060;GO:0010038//response to metal ion;GO:0007166//cell surface receptor signaling pathway;GO:0006811//ion transport;GO:0023060;GO:0010038//response to metal ion 34165 984.00 1.13 0.57 -0.987288948250446 Down 0.258783516048078 CG13386 CG13386 - - - - 42339 2889.51 45.91 33.84 -0.440078863592416 Down 0.578985602958658 CG6231 CG6231, isoform F K08202|1|9e-53|209|aag:AaeL_AAEL012443|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 35342 1092.00 79.97 72.055 -0.150360343339029 Down 0.336217144366662 Pomp pomp K11599|1|1e-73|276|dme:Dmel_CG9324|proteasome maturation protein - - GO:0019538//protein metabolic process;GO:0007052//mitotic spindle organization 8674069 1225.00 0.27 0.42 0.637429920615292 Up 0.118181217804781 CG42585 CG42585 - GO:0044464//cell part GO:0046914//transition metal ion binding - 2768687 3462.46 61.05 60.455 -0.0141296310584308 Down 0.0672302205785233 LpR1 lipophorin receptor 1, isoform S K12473|1|2e-171|603|xla:373644|low-density lipoprotein receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis 12798360 800.00 0.24 0.285 0.247927513443586 Up 0.0625742966583014 32453 1055.00 0.26 0.25 -0.0565835283663676 Down 0.0422335226522256 PPYR1 protein phosphatase Y regulator 1 K13199|1|2e-13|76.6|dpe:Dper_GL25726|plasminogen activator inhibitor 1 RNA-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome - GO:0034968//histone lysine methylation;GO:0035194//posttranscriptional gene silencing by RNA 19834875 741.00 0.11 0.125 0.184424571137428 Up 0.0511161009113723 43347 1246.00 6.54 6.01 -0.121925644786897 Down 0.157541936336019 CG12259 CG12259 K13119|1|1e-155|549|dme:Dmel_CG12259|protein FAM50 GO:0043231//intracellular membrane-bounded organelle - - 33638 2361.00 6.055 4.4 -0.460623436169669 Down 0.37488442742042 Traf4 TNF-receptor-associated factor 4, isoform E K09848|1|0.0|907|der:Dere_GG24997|TNF receptor-associated factor 4 GO:0044448//cell cortex part;GO:0044448//cell cortex part GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0007166//cell surface receptor signaling pathway;GO:0006909//phagocytosis;GO:0007423//sensory organ development;GO:0043410//positive regulation of MAPK cascade;GO:0002164//larval development;GO:0009886//post-embryonic morphogenesis;GO:0048102//autophagic cell death;GO:0008105//asymmetric protein localization;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0006909//phagocytosis;GO:0007423//sensory organ development;GO:0043410//positive regulation of MAPK cascade;GO:0002164//larval development;GO:0009886//post-embryonic morphogenesis;GO:0048102//autophagic cell death;GO:0008105//asymmetric protein localization;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0006950//response to stress 3772624 821.09 5.585 9.19 0.71850758080572 Up 0.528926165632017 36401 631.00 0.115 0.36 1.6463630453853 Up 0.178080834764232 wuc Wake-up-call, isoform B - - - - 2768962 509.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 CG6244 CG6244 - - - - 43562 1792.30 330.24 377.745 0.193897783492621 Up 0.414839519218069 CG7920 CG7920, isoform C - GO:0044444//cytoplasmic part GO:0016787//hydrolase activity GO:0006732//coenzyme metabolic process 33774 2168.00 12.425 15.64 0.331994660857704 Up 0.433430194161934 CG7371 CG7371 - - - - 4379891 4457.00 5.445 5.515 0.0184288368744757 Up 0.0542200501915203 CG34106 CG34106, isoform B - - - - 37232 2617.35 47.005 46.995 -0.000306956392836166 Down 0.0401862369568089 CalpA Calpain-A, isoform D K08585|1|0.0|1131|dme:Dmel_CG7563|calpain, invertebrate [EC:3.4.22.-] - - - 31581 3588.04 77.6 82.015 0.0798311408127994 Up 0.211365737683265 Marf mitochondrial assembly regulatory factor, isoform D K06030|1|0.0|1553|dme:Dmel_CG3869| [EC:3.6.5.-] - - - 40181 916.95 11.29 10.43 -0.114306328253235 Down 0.185576542068419 CG14182 CG14182, isoform D - - - - 38783 429.00 3.02 0.115 -4.71484278326807 Down 0.661669528463875 CG8628 CG8628, isoform B K08762|1|2e-17|87.0|xla:444376|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) - GO:0008144//drug binding;GO:0030234//enzyme regulator activity;GO:0005504//fatty acid binding;GO:0008144//drug binding;GO:0030234//enzyme regulator activity;GO:0005504//fatty acid binding GO:0055082//cellular chemical homeostasis;GO:0055082//cellular chemical homeostasis 3885612 1598.00 0.465 0.19 -1.29123129766445 Down 0.183859463743231 ppk16 pickpocket 16 K04832|1|2e-23|110|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|2|3e-11|70.1|spu:575477|amiloride-sensitive cation channel 2, neuronal;K04831|4|2e-06|54.3|dre:407668|amiloride-sensitive cation channel 4, pituitary GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 35877 4115.40 18.955 19.79 0.0621931558768681 Up 0.14377228899749 sec31 Sec31 ortholog, isoform D K14005|1|0.0|2166|dme:Dmel_CG8266|protein transport protein SEC31 GO:0044431//Golgi apparatus part;GO:0030529//ribonucleoprotein complex;GO:0030133//transport vesicle;GO:0044431//Golgi apparatus part;GO:0030529//ribonucleoprotein complex;GO:0030133//transport vesicle - GO:0006396//RNA processing;GO:0006396//RNA processing 326130 2102.00 1.26 1.82 0.53051471669878 Up 0.230847972526747 CG31272 CG31272 K06258|1|9e-68|258|tca:660155|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 - GO:0016788//hydrolase activity, acting on ester bonds GO:0006810//transport;GO:0044238//primary metabolic process 38420 3427.65 63.67 67.775 0.0901394438412374 Up 0.22787610619469 YT521-B YT521-B, isoform B - - - - 34218 1935.00 1.695 0.315 -2.42786153963643 Down 0.452912429005415 CG32984 CG32984 - - - - 10178853 403.00 0.84 1.295 0.624490864907794 Up 0.210110949676397 CG42866 CG42866 - - - - 318143 1250.00 1.805 2.485 0.461247014675115 Up 0.24861312904504 CG32655 CG32655 - - GO:0003824//catalytic activity GO:0008152//metabolic process 42636 3080.01 0.065 0.09 0.46948528330122 Up 0.0547483819838859 CG13847 CG13847, isoform C - - - - 33036 1072.00 1.19 1.645 0.467126010427298 Up 0.204398362171444 CG15459 CG15459 - - - - 246493 3894.42 29.195 38.555 0.401196656855438 Up 0.550323603222824 prom prominin, isoform E K06532|1|2e-19|99.0|mdo:100015509|prominin GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 38603 1451.00 22.46 22.01 -0.029198782509044 Down 0.0950336811517633 CG4603 CG4603, isoform C K13719|1|2e-175|615|dme:Dmel_CG4603|ubiquitin thioesterase OTU1 [EC:3.1.2.-] - GO:0016790//thiolester hydrolase activity;GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0044237//cellular metabolic process 33654 586.85 1228.65 1068.555 -0.201412832774517 Down 0.432208426892088 RpL27A ribosomal protein L27A, isoform D K02900|1|8e-71|266|dya:Dyak_GE14714|large subunit ribosomal protein L27Ae GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 32759 531.00 0.08 0.01 -3 Down 0.110718531237617 CG12986 CG12986 - - - - 35599 1315.59 0.08 0.265 1.7279204545632 Up 0.153348302734117 Spn42Db serpin 42Db, isoform D K13963|1|4e-74|278|dgr:Dgri_GH19862|serpin B - GO:0004866//endopeptidase inhibitor activity GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing 12798229 687.00 0.175 0.43 1.29698173775713 Up 0.179665830141329 31328 1044.00 0.825 0.465 -0.827163403137784 Down 0.198355567296262 Ilp7 Insulin-like peptide 7 - - - - 42807 897.71 13.685 12.19 -0.166897308744744 Down 0.269515255580505 Plip PTEN-like phosphatase, isoform B K06639|1|8e-09|60.8|tad:TRIADDRAFT_27920|cell division cycle 14 [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 31667 3487.00 3.985 3.225 -0.305280563679856 Down 0.24385814291375 Dok downstream of kinase K12461|1|3e-07|58.2|dre:436931|fibroblast growth factor receptor substrate 2 - - - 42819 8143.43 14.395 18.045 0.326031354333798 Up 0.446638488971074 eIF4G2 eukaryotic translation initiation factor 4G2, isoform C K03260|1|5e-78|294|dse:Dsec_GM26760|translation initiation factor eIF-4F - GO:0003723//RNA binding GO:0044260;GO:0007052//mitotic spindle organization 32196 2960.17 50.915 59.275 0.219333008330245 Up 0.420519085985999 CG42258 CG42258, isoform F - - - - 43836 3576.56 34.325 36.36 0.083092479159644 Up 0.196143177915731 CG32016 eIF4E-Transporter, isoform H - - - - 42494 978.00 0.05 0.145 1.53605290024021 Up 0.110223220182274 dmrt93B doublesex-Mab related 93B - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction 36810 3718.00 47.305 46.06 -0.0384782691351678 Down 0.12650244353454 Khc kinesin heavy chain K10396|1|0.0|1763|dme:Dmel_CG7765|kinesin family member 5 GO:0043231//intracellular membrane-bounded organelle;GO:0005875//microtubule associated complex GO:0003777//microtubule motor activity;GO:0032559;GO:0015631//tubulin binding GO:0010970//microtubule-based transport;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006935//chemotaxis;GO:0046530//photoreceptor cell differentiation;GO:0007005//mitochondrion organization;GO:0001505//regulation of neurotransmitter levels;GO:0007300//ovarian nurse cell to oocyte transport 38832 659.00 1.21 2.5 1.04692104738749 Up 0.392286355831462 CG14835 CG14835 - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39808 3472.79 0.555 0.415 -0.419376435003181 Down 0.109562805441817 CG4998 CG4998, isoform B K01312|1|8e-47|189|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|2|2e-41|171|hsa:3818|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 37195 1445.00 1.58 3.775 1.25655208603534 Up 0.493230748910316 CG15109 CG15109, isoform E - - - - 37435 4914.94 89.96 65.65 -0.454488649997567 Down 0.607614581957469 CG9485 CG9485, isoform F K01196|1|0.0|3145|dme:Dmel_CG9485|glycogen debranching enzyme [EC:2.4.1.25 3.2.1.33] - GO:0043167//ion binding;GO:0004133//glycogen debranching enzyme activity;GO:0043167//ion binding;GO:0004133//glycogen debranching enzyme activity GO:0005977//glycogen metabolic process;GO:0005977//glycogen metabolic process 40999 1411.21 59.675 65.21 0.127966558427841 Up 0.299432043323207 stck steamer duck, isoform D K05760|1|5e-39|162|phu:Phum_PHUM437870|paxillin GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0043409//negative regulation of MAPK cascade;GO:0001700//embryonic development via the syncytial blastoderm;GO:0043409//negative regulation of MAPK cascade;GO:0001700//embryonic development via the syncytial blastoderm;GO:0043409//negative regulation of MAPK cascade;GO:0001700//embryonic development via the syncytial blastoderm 31203 893.00 0.05 0.17 1.76553474636298 Up 0.123794743098666 CG14052 CG14052 - - - - 33147 2644.00 0.13 0.225 0.791413378188582 Up 0.0976092986395456 CG12446 CG12446 - - - - 38974 917.12 72.82 66.395 -0.133260139975435 Down 0.302635054814423 GstO2 glutathione S transferase O2, isoform B K00310|1|2e-58|226|dme:Dmel_CG6781|pyrimidodiazepine synthase [EC:1.5.4.1];K00799|1|2e-58|226|dme:Dmel_CG6781|glutathione S-transferase [EC:2.5.1.18] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016648;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0016648;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0010259//multicellular organismal aging;GO:0006950//response to stress;GO:0010259//multicellular organismal aging;GO:0006950//response to stress 38004 2237.00 0.35 0.175 -1 Down 0.14377228899749 gsb-n gooseberry-neuro K09381|1|0.0|746|dme:Dmel_CG2692|paired box protein 3/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0007365//periodic partitioning;GO:0006351//transcription, DNA-dependent 50161 608.00 22.045 7.6 -1.5363801532848 Down 0.71605468234051 CG12483 CG12483 - - - - 50315 445.00 0.48 0.715 0.574908836057233 Up 0.14400343415665 CG15212 CG15212 - - - - 3355093 2990.00 25.645 29.04 0.179363882018433 Up 0.339155989961696 CG40470 CG40470 K11140|1|2e-95|350|ame:412808|aminopeptidase N [EC:3.4.11.2] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 35578 5117.35 13.645 11.52 -0.244231677831828 Down 0.341764628186501 CG3409 CG3409, isoform C K08190|1|2e-31|139|mdo:100014050|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14 - - GO:0006810//transport;GO:0006810//transport 41132 913.00 10.115 6.755 -0.582468645232598 Down 0.50069343547748 GstZ1 glutathione S transferase Z1 K00799|1|4e-143|507|dme:Dmel_CG9362|glutathione S-transferase [EC:2.5.1.18];K01800|1|4e-143|507|dme:Dmel_CG9362|maleylacetoacetate isomerase [EC:5.2.1.2] GO:0044424//intracellular part GO:0016859//cis-trans isomerase activity GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process 31007 1175.00 23.97 20.695 -0.211947660418842 Down 0.361940298507463 CG13369 CG13369 K00852|1|5e-161|566|dme:Dmel_CG13369|ribokinase [EC:2.7.1.15] - - - 35128 1134.00 76.665 76.07 -0.0112404870100585 Down 0.0672302205785233 Jwa Jwa ortholog - - GO:0015075//ion transmembrane transporter activity GO:0006810//transport 35754 1632.54 18.185 17.935 -0.0199711804980924 Down 0.0730088495575221 CG2915 CG2915, isoform B K01290|1|2e-74|280|dpo:Dpse_GA20041|carboxypeptidase A, invertebrate [EC:3.4.17.-] GO:0043226//organelle;GO:0043226//organelle GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 19835872 1121.00 1.11 1.5 0.434402824145775 Up 0.184684982168802 40565 1108.00 11.095 12.28 0.146400893173168 Up 0.237650244353454 CG9804 CG9804 K03801|1|7e-136|483|dme:Dmel_CG9804|lipoyl(octanoyl) transferase [EC:2.3.1.181] GO:0044424//intracellular part GO:0008415 GO:0009105;GO:0043412//macromolecule modification 35379 1669.00 19.845 21.73 0.13091261218145 Up 0.256538105930524 CG9253 CG9253 K01529|1|0.0|801|dpo:Dpse_GA21647| [EC:3.6.1.-] - GO:0032559;GO:0042623//ATPase activity, coupled - 7354452 1265.00 0.125 0.17 0.443606651475615 Up 0.0738343679830934 35372 1353.00 1.38 2.17 0.65302677566631 Up 0.283747193237353 CG9259 CG9259, isoform C - - - - 43450 4933.01 13.485 10.88 -0.309676964985264 Down 0.4013010170387 CG11897 CG11897, isoform B K10835|1|0.0|1260|dme:Dmel_CG11898|xenobiotic-transporting ATPase [EC:3.6.3.44];K05673|2|0.0|1075|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|3|0.0|971|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015405;GO:0005253//anion channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport;GO:0006810//transport 39346 1671.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG5897 CG5897 K01873|1|1e-07|58.2|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 41286 2849.14 3.17 3.64 0.199455610059289 Up 0.169990754193634 Takr86C Tachykinin-like receptor at 86C, isoform B K04225|1|0.0|1022|dsi:Dsim_GD20709|tachykinin receptor, invertebrate GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 14462484 722.00 4.66 3.545 -0.394544327414764 Down 0.306927750627394 Rpb4 Rpb4 K03012|1|7e-74|276|dme:Dmel_CG33520|DNA-directed RNA polymerase II subunit D;K11314|5|9e-61|233|dsi:Dsim_GD20190|transcriptional adapter 2-alpha GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter 36521 5883.04 15.175 17.21 0.181550580897159 Up 0.302535992603355 fas faint sausage, isoform B K06578|1|5e-14|81.6|dre:767689|Lutheran blood group glycoprotein;K06780|2|5e-11|71.6|mdo:100030156|immunoglobulin superfamily, member 4B;K06782|4|1e-10|70.5|oaa:100084847|immunoglobulin superfamily, member 4D GO:0044464//cell part - - 43873 2431.52 59.445 63.16 0.0874557031710969 Up 0.226291110817593 ras raspberry, isoform E K00088|1|0.0|1029|der:Dere_GG18365|IMP dehydrogenase [EC:1.1.1.205] - GO:0043169//cation binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0043169//cation binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0043169//cation binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006909//phagocytosis;GO:0006935//chemotaxis;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006909//phagocytosis;GO:0006935//chemotaxis;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006909//phagocytosis;GO:0006935//chemotaxis;GO:0009168//purine ribonucleoside monophosphate biosynthetic process 43400 2150.00 10.32 10.67 0.0481172054011709 Up 0.103123761722362 CG1523 CG1523 K11802|1|0.0|1146|dme:Dmel_CG1523|WD repeat-containing protein 32 - - - 3771982 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 42433 1154.16 25.895 25.35 -0.0306878112401454 Down 0.0982036719059569 TFAM mitochondrial transcription factor A, isoform B K11830|1|2e-137|488|dme:Dmel_CG4217|transcription factor A, mitochondrial GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0006261//DNA-dependent DNA replication;GO:0006355//regulation of transcription, DNA-dependent;GO:0006261//DNA-dependent DNA replication 318892 3974.89 0.46 0.695 0.595379116666495 Up 0.148263109232598 CG33125 CG33125, isoform C - - - - 31267 1804.00 2.775 2.9 0.0635651287774661 Up 0.0714238541804253 CG2712 CG2712 K09228|1|1e-49|197|cfa:484460|KRAB domain-containing zinc finger protein - - - 40822 725.00 1.525 1.365 -0.159908291530396 Down 0.096420552106723 Ccp84Ad Ccp84Ad - - GO:0042302//structural constituent of cuticle - 326159 2493.00 1.45 2.25 0.633872101202103 Up 0.284044379870559 CG31773 CG31773 K01930|1|0.0|1352|dme:Dmel_CG31773|folylpolyglutamate synthase [EC:6.3.2.17] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0006760//folic acid-containing compound metabolic process 39530 2429.00 55.875 43.29 -0.368169125745688 Down 0.550488706907938 CG8745 CG8745 K00837|1|2e-146|520|xla:446472| [EC:2.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0008483//transaminase activity;GO:0048037//cofactor binding GO:0006527//arginine catabolic process 42129 1176.00 8.33 9.97 0.259277009032648 Up 0.320829480914014 CG31249 CG31249 - - - - 36015 1090.91 62.09 63.11 0.0235076916942569 Up 0.0881653678510104 CG1599 Vesicle-associated membrane protein 7, isoform C K08515|1|2e-121|435|dme:Dmel_CG1599|vesicle-associated membrane protein 7 GO:0031224//intrinsic to membrane GO:0005515//protein binding GO:0006810//transport 40092 1729.53 7.58 6.985 -0.117937732761629 Down 0.166292431647074 rept reptin, isoform C K11338|1|0.0|864|dsi:Dsim_GD14791|RuvB-like protein 2 [EC:3.6.1.-] GO:0015630//microtubule cytoskeleton;GO:0043189//H4/H2A histone acetyltransferase complex;GO:0035097//histone methyltransferase complex;GO:0000790//nuclear chromatin;GO:0031519//PcG protein complex GO:0003712//transcription cofactor activity;GO:0004468//lysine N-acetyltransferase activity;GO:0004386//helicase activity;GO:0032559 GO:0016458//gene silencing;GO:0016570//histone modification;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0006259//DNA metabolic process;GO:0035466 33460 1730.00 5.695 6.205 0.123735368422245 Up 0.154933298111214 Cwc25 Cwc25 K08823|1|2e-08|60.8|cel:F52C9.7|CDC-like kinase [EC:2.7.12.1] - GO:0046914//transition metal ion binding GO:0015031//protein transport 31535 1391.14 7.905 9.52 0.268196110949573 Up 0.323074891031568 rux roughex, isoform B - - - - 37185 4415.24 23.04 17.495 -0.397198052202463 Down 0.513241315546163 sano serrano, isoform F - - - - 41643 1434.00 0.74 1.69 1.19142607065323 Up 0.345363888521992 Lip3 Lip3 K01046|1|2e-106|385|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01052|5|1e-73|277|ssc:100142668|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - - - 33079 765.00 4.185 4.53 0.114283427495891 Up 0.125148593316603 CG15449 CG15449 - - - - 43729 6616.00 14.07 17.4 0.306464977499558 Up 0.427420420023775 kek6 kek6, isoform B K07523|1|6e-45|182|dme:Dmel_CG4192|netrin-G1 ligand;K08462|2|5e-15|83.6|tgu:100222766|G protein-coupled receptor 125;K06850|4|1e-14|82.4|xtr:780195|slit 3 - - - 39527 8720.66 30.225 38.015 0.330826451597623 Up 0.506406022982433 bru-3 bruno-3, isoform O K13207|1|0.0|738|dya:Dyak_GE20053|CUG-BP- and ETR3-like factor GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0005488//binding;GO:0005488//binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0005488//binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding - 8674106 333.00 0.705 0.01 -6.13955135239879 Down 0.42887333245278 CG42578 CG42578 - - - - 41472 1375.00 3.305 0.855 -1.95065394662179 Down 0.54101175538238 CG4702 CG4702, isoform D - - - - 19835814 705.00 0.23 0.72 1.6463630453853 Up 0.264694227975168 39801 513.00 9.46 3.47 -1.44690452076113 Down 0.645258222163519 CG13041 CG13041 - - - - 64872 1390.00 7.545 8.05 0.0934678824752962 Up 0.141394795931845 MESK4 misexpression suppressor of KSR 4, isoform B - - GO:0005488//binding - 37521 3718.55 24.47 24.465 -0.00029481864634914 Down 0.0382380134724607 Vrp1 verprolin 1, isoform L - GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part;GO:0030175//filopodium;GO:0044424//intracellular part GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0030041//actin filament polymerization 37935 2248.00 5.52 5.04 -0.131244533278253 Down 0.155065381059305 CG4707 CG4707 K09228|1|4e-39|163|mcc:702737|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 43483 1623.00 102.13 91.8 -0.153840651674325 Down 0.342226918504821 CG1907 CG1907 K13577|1|5e-47|189|dwi:Dwil_GK13938|mitochondrial dicarboxylate carrier GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part GO:0005215//transporter activity GO:0046907//intracellular transport;GO:0015740//C4-dicarboxylate transport 35732 1961.00 10.295 12.08 0.230676624692825 Up 0.318914278166689 CG1550 CG1550 K06047|1|1e-08|62.0|ecb:100052052|tubulin---tyrosine ligase [EC:6.3.2.25];K05755|4|5e-08|59.7|ecb:100058358|actin related protein 2/3 complex, subunit 4 - GO:0016881//acid-amino acid ligase activity GO:0043412//macromolecule modification 42211 1136.57 84.52 94.535 0.16155579463163 Up 0.355402192576938 CG7675 CG7675, isoform E K11162|1|1e-62|240|mcc:700458|retinol dehydrogenase 14 [EC:1.1.1.-];K11153|4|2e-62|239|tgu:100226769|retinol dehydrogenase 12 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 43258 1513.90 177.87 55.38 -1.68338624374403 Down 0.774072117289658 Cpr97Ea cuticular protein 97Ea, isoform B - - - - 19836127 450.00 0.39 0.01 -5.28540221886225 Down 0.314984810460969 42133 3186.76 9.65 10.01 0.052841126680551 Up 0.104411570466253 Lgr1 Leucine-rich repeat-containing G protein-coupled receptor 1, isoform B K04248|1|0.0|1571|dme:Dmel_CG7665|luteinizing hormone/choriogonadotropin receptor;K04249|5|3e-101|370|mdo:100021427|thyroid stimulating hormone receptor - - - 19835261 370.00 1.085 0.86 -0.335286477742381 Down 0.130861180821556 31193 1822.00 5.905 8.56 0.535673737003989 Up 0.460705322942808 Cyp4ae1 cytochrome P450-4ae1 K00517|1|0.0|960|dme:Dmel_CG10755| [EC:1.14.-.-] - - - 40283 2245.00 8.195 5.705 -0.522517062810777 Down 0.446968696341302 Rcd2 reduction in Cnn dots 2 K08706|1|7e-150|531|dya:Dyak_GE22392|nuclear receptor subfamily 0 group A;K06236|2|6e-08|59.7|cfa:478836|collagen, type I/II/III/V/XI, alpha - GO:0005488//binding GO:0006350 249663 3383.32 135.315 154.29 0.189322785057298 Up 0.406551314225334 hoe1 hoepel1, isoform J - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006842//tricarboxylic acid transport;GO:0006842//tricarboxylic acid transport;GO:0006842//tricarboxylic acid transport;GO:0006842//tricarboxylic acid transport;GO:0006842//tricarboxylic acid transport;GO:0006842//tricarboxylic acid transport 326198 1354.00 22.785 22.685 -0.00634571087249529 Down 0.0547483819838859 Krn keren K02447|1|3e-08|59.7|dpo:Dpse_GA25451|protein gruken precursor;K05455|2|1e-07|58.2|rno:112400|neuregulin 1 GO:0043231//intracellular membrane-bounded organelle GO:0070851//growth factor receptor binding GO:0001654//eye development;GO:0007243//intracellular protein kinase cascade;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007297//ovarian follicle cell migration;GO:0007389//pattern specification process 37496 790.00 0.155 0.3 0.952694285221644 Up 0.12696473385286 CG13488 CG13488, isoform C - - - - 319021 905.00 0.515 1.11 1.10791533916689 Up 0.274633469819046 CG31910 CG31910 - - - - 326189 701.00 86.935 72.35 -0.264944105743756 Down 0.474640073966451 CG32068 CG32068 K08967|1|1e-109|395|dme:Dmel_CG32068|1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54] - GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0043102 36771 6078.81 25.075 29.085 0.214025603328406 Up 0.375775987320037 SP2353 SP2353, isoform B K06254|1|4e-56|221|dre:565373|agrin - - - 37382 1853.00 45.56 35.76 -0.349421010524794 Down 0.52965262184652 CG3295 CG3295 K12842|1|5e-06|53.1|dsi:Dsim_GD11555|U2-associated protein SR140 - - - 40856 513.00 0.245 0.185 -0.405256478486259 Down 0.0775326905296526 CG14610 CG14610 - - - - 31145 561.04 56.105 55.72 -0.00993408961089941 Down 0.0657442874124951 CG14817 CG14817, isoform B - - - - 37795 4608.00 4.985 5.25 0.0747239181552889 Up 0.0983027341170255 Lpt lost PHDs of trr, isoform B K09188|1|3e-133|477|spu:591084|myeloid/lymphoid or mixed-lineage leukemia protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0006909//phagocytosis;GO:0023033 42750 2744.00 4.68 4.715 0.010749241091692 Up 0.0472856954167217 wda will decrease acetylation K03130|1|2e-127|457|aag:AaeL_AAEL002802|transcription initiation factor TFIID subunit D4 GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression;GO:0016570//histone modification 5740103 1590.00 0.075 0.215 1.51937415909358 Up 0.13079513934751 CG34216 CG34216 - - - - 35520 1949.57 5.71 1.2 -2.25045633975432 Down 0.640833443402457 CG7882 CG7882, isoform C K07299|1|6e-69|261|mdo:100026702|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1;K08142|3|5e-68|258|bta:282358|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3 GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity GO:0006810//transport 39756 1149.00 0.67 0.21 -1.67377176767901 Down 0.256240919297319 CG13075 CG13075 - - GO:0030247//polysaccharide binding GO:0006022 41346 1250.00 19.615 20.21 0.0431119863026398 Up 0.111742174085326 CG6693 CG6693, isoform B K09529|1|9e-148|523|dme:Dmel_CG6693|DnaJ homolog subfamily C member 9 - GO:0005515//protein binding - 35218 2291.41 8.705 8.365 -0.0574787576127484 Down 0.106987187954035 CG16771 CG16771, isoform E K01077|1|0.0|1193|dme:Dmel_CG16771|alkaline phosphatase [EC:3.1.3.1] - GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity - 36562 1475.00 5.97 6.59 0.142547533743247 Up 0.177882710342095 CG13016 CG13016 - - - - 36570 546.00 25.845 32.025 0.309313368282905 Up 0.47926297714965 mRpS16 mitochondrial ribosomal protein S16, isoform C - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 42235 1846.00 10.485 4.795 -1.12872414107846 Down 0.621351208558975 CG14301 CG14301 - - GO:0030247//polysaccharide binding GO:0006022 42627 1435.00 1.33 3.27 1.29786438999689 Up 0.476192048606525 CG13857 CG13857 - - - - 318953 584.00 0.21 0.08 -1.39231742277876 Down 0.12534671773874 CG31807 CG31807, isoform B K08849|1|3e-08|58.5|gga:415684|mixed lineage kinase domain-like [EC:2.7.11.1] - GO:0046914//transition metal ion binding - 38138 1083.00 2.735 4.59 0.746953320621251 Up 0.431085721833311 CG9129 CG9129 - - - - 43667 2608.00 0.16 0.37 1.20945336562895 Up 0.157971205917316 CG15548 CG15548 - - - - 317967 3495.00 0.02 0.085 2.08746284125034 Up 0.0908070268128385 CG32305 CG32305 K01768|1|0.0|2173|dme:Dmel_CG32305|adenylate cyclase [EC:4.6.1.1];K03458|5|1e-149|531|der:Dere_GG23802|nucleobase:cation symporter-2, NCS2 family GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0006164//purine nucleotide biosynthetic process;GO:0009124//nucleoside monophosphate biosynthetic process 5740380 740.00 61.51 73.515 0.257217671527302 Up 0.468927486461498 34481 2715.00 6.41 6.72 0.0681368761600193 Up 0.106557918372738 Nup107 nucleoporin 107kD - GO:0005635//nuclear envelope - GO:0051234//establishment of localization 39834 3436.00 3.285 3.72 0.179409250785702 Up 0.160249636771893 CG33158 CG33158 K03234|1|0.0|1947|dme:Dmel_CG33158|elongation factor EF-2 [EC:3.6.5.3] - GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding - 43152 978.00 11.73 10.57 -0.150227636645825 Down 0.235239730550786 E(spl)mbeta-HLH enhancer of split mbeta, helix-loop-helix K09090|1|1e-107|389|dme:Dmel_CG14548|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0001654//eye development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007166//cell surface receptor signaling pathway 31938 1553.00 54.645 28.695 -0.92929012139667 Down 0.700336811517633 Yp2 yolk protein 2, isoform B K01059|1|2e-29|130|dpo:Dpse_GA19044|lipoprotein lipase [EC:3.1.1.34];K01046|4|1e-14|81.6|dme:Dmel_CG5966|triacylglycerol lipase [EC:3.1.1.3] GO:0005678//chromatin assembly complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton - GO:0007028//cytoplasm organization;GO:0003006//developmental process involved in reproduction;GO:0044238//primary metabolic process 36556 477.00 1.315 1.8 0.452934107037372 Up 0.20783251882182 CG18371 CG18371 K01512|1|6e-59|225|dme:Dmel_CG18371|acylphosphatase [EC:3.6.1.7] - GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides - 41289 3990.49 8.035 9.015 0.166029467757248 Up 0.229428080834764 Cap-H2 chromosome associated protein H2, isoform G K11490|1|1e-07|58.9|xla:447709|condensin-2 complex subunit H2 GO:0000793//condensed chromosome;GO:0000793//condensed chromosome;GO:0000793//condensed chromosome;GO:0000793//condensed chromosome - GO:0051322//anaphase;GO:0007140//male meiosis;GO:0007135//meiosis II;GO:0006996//organelle organization;GO:0051322//anaphase;GO:0007140//male meiosis;GO:0007135//meiosis II;GO:0006996//organelle organization;GO:0051322//anaphase;GO:0007140//male meiosis;GO:0007135//meiosis II;GO:0006996//organelle organization;GO:0051322//anaphase;GO:0007140//male meiosis;GO:0007135//meiosis II;GO:0006996//organelle organization 19835557 599.00 0.48 0.165 -1.5405683813627 Down 0.207766477347774 318000 1870.71 1.4 2.22 0.665132849405139 Up 0.289492801479329 CG32373 CG32373, isoform C K06825|1|1e-26|121|gga:373992|fibrillin 1 - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 39065 2144.28 246.88 206.97 -0.254388300687136 Down 0.480847972526747 UGP UGP, isoform E K00963|1|0.0|1034|dsi:Dsim_GD12937|UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups - 39383 469.00 33.29 22.515 -0.564202392798418 Down 0.608175934486858 Atg12 Autophagy-specific gene 12 K08336|1|6e-61|233|dme:Dmel_CG10861|autophagy-related protein 12 GO:0044424//intracellular part - GO:0048102//autophagic cell death;GO:0044248//cellular catabolic process;GO:0007033//vacuole organization 318189 1603.00 0.05 0.03 -0.736965594166206 Down 0.0552767137762515 CG32751 CG32751, isoform B K01435|1|0.0|771|dme:Dmel_CG32754|biotinidase [EC:3.5.1.12];K08069|4|9e-38|158|ecb:100067672|pantetheine hydrolase [EC:3.5.1.92] GO:0044425//membrane part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0008152//metabolic process 36679 2000.00 1.87 1.17 -0.676529740304232 Down 0.269251089684322 CG8089 CG8089 K10513|1|1e-17|91.7|rno:289052|zinc finger and BTB domain-containing protein 41;K10519|3|2e-17|91.3|mcc:704628|zinc finger and BTB domain-containing protein 48 GO:0044464//cell part GO:0046914//transition metal ion binding - 317944 803.00 0.25 0.39 0.641546029087524 Up 0.114681019680359 CG32263 CG32263 K13348|1|2e-20|99.0|tgu:100229975|protein Mpv17;K13347|2|6e-13|74.3|rno:29533|peroxisomal membrane protein 2 GO:0031224//intrinsic to membrane - - 35437 1107.00 0.385 0.74 0.942666824934048 Up 0.204464403645489 ttm3 tiny tim 3 K01090|1|6e-18|91.7|bta:516199|protein phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization 5740879 1172.37 5.445 4.295 -0.342273917578443 Down 0.302205785233126 CG34367 CG34367, isoform E K09331|1|1e-40|167|dre:394171|short stature homeobox protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048513//organ development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048513//organ development 19834810 922.00 0.145 0.19 0.389946518316013 Up 0.0673292827895919 19834994 535.00 0.17 0.375 1.14135584924554 Up 0.152985074626866 41425 5086.50 28.56 32.055 0.166553429351868 Up 0.331528199709417 CG17360 CG17360, isoform B K05750|1|2e-14|82.4|cqu:CpipJ_CPIJ002287|NCK-associated protein 1 - - - 42508 1038.00 11.56 13.84 0.259702545136046 Up 0.359959054286092 CG7009 CG7009 K00599|1|7e-175|612|dme:Dmel_CG7009| [EC:2.1.1.-];K02427|3|2e-110|398|dvi:Dvir_GJ22540|ribosomal RNA large subunit methyltransferase E [EC:2.1.1.-] GO:0044424//intracellular part GO:0005488//binding;GO:0008171//O-methyltransferase activity GO:0006730//one-carbon metabolic process;GO:0000154//rRNA modification 19835076 423.00 0.105 0.14 0.415037499278844 Up 0.0678576145819575 34250 1147.00 0.66 0.505 -0.386182636606659 Down 0.115605600316999 Cks30A Cyclin-dependent kinase subunit 30A K02219|1|2e-30|133|dya:Dyak_GE18832|cyclin-dependent kinase regulatory subunit CKS1 GO:0031981//nuclear lumen GO:0004674//protein serine/threonine kinase activity;GO:0019887//protein kinase regulator activity;GO:0005488//binding GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0016310//phosphorylation;GO:0007056//spindle assembly involved in female meiosis;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process;GO:0007560//imaginal disc morphogenesis;GO:0030071//regulation of mitotic metaphase/anaphase transition 31603 2790.00 2.635 2.64 0.00273496772123889 Up 0.0401862369568089 Mcm6 minichromosome maintenance 6 K02542|1|0.0|1570|dme:Dmel_CG4039|minichromosome maintenance protein 6 - - - 14462411 1224.00 0.39 0.275 -0.504042505337589 Down 0.10460969488839 CG43843 CG43843 - - - - 32752 3032.00 21.935 27.39 0.320414559686148 Up 0.477677981772553 par-6 par-6, isoform B K06093|1|8e-164|578|dme:Dmel_CG5884|partitioning defective protein 6 GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part GO:0005488//binding GO:0006909//phagocytosis;GO:0007043//cell-cell junction assembly;GO:0033673//negative regulation of kinase activity;GO:0065008;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030010//establishment of cell polarity;GO:0007399//nervous system development 34748 2288.56 7.975 8.02 0.00811771780268865 Up 0.0472856954167217 CG9305 CG9305, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - 33006 1129.00 0.14 0.305 1.12338241550528 Up 0.136573768326509 CG17003 CG17003 - - - - 33690 4756.90 20.37 23.965 0.234482959653075 Up 0.384130233786818 pog poor gastrulation, isoform F K08469|1|7e-42|173|bfo:BRAFLDRAFT_66969|G protein-coupled receptor 158 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 31737 1155.00 1.645 1.165 -0.497757629080961 Down 0.211431779157311 CG2120 CG2120 K09228|1|1e-38|161|cfa:484247|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 42802 1360.62 144.85 71.91 -1.01029536978748 Down 0.730517765156518 Rpn9 regulatory particle non-ATPase 9, isoform B K03039|1|0.0|728|dme:Dmel_CG10230|26S proteasome regulatory subunit N9 GO:0005838//proteasome regulatory particle;GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0007346//regulation of mitotic cell cycle;GO:0019538//protein metabolic process;GO:0007346//regulation of mitotic cell cycle 32754 5846.74 16.045 17.945 0.16145813353427 Up 0.282228239334302 CG42684 CG42684, isoform I K04352|1|1e-40|169|bfo:BRAFLDRAFT_206850|Ras GTPase-activating protein 1 - - GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction 42718 1076.00 106.425 84.725 -0.328977453297714 Down 0.544511953506802 CG13833 CG13833 K11151|1|2e-25|116|gga:420183|retinol dehydrogenase 10 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 5740782 860.00 1.045 1.67 0.67634516039317 Up 0.252608638224805 whip whipple - - - - 19835701 5961.81 1.37 0.365 -1.90820752408051 Down 0.381224408928807 31588 1030.29 940.575 1073.745 0.191036521601393 Up 0.418967111345925 RpL7A ribosomal protein L7A, isoform G K02936|1|1e-132|472|dya:Dyak_GE16459|large subunit ribosomal protein L7Ae - - - 33927 2418.00 0.24 0.15 -0.678071905112638 Down 0.0954299299960375 Oatp26F organic anion transporting polypeptide 26F - GO:0044464//cell part GO:0008509//anion transmembrane transporter activity GO:0051234//establishment of localization 33943 1703.00 6.62 7.345 0.149931273749062 Up 0.195713908334434 CG11188 apoptosis antagonizing transcription factor ortholog - GO:0043231//intracellular membrane-bounded organelle - - 12798081 358.00 1.085 2.595 1.2580394959134 Up 0.428741249504689 CG43267 CG43267 - - - - 36272 3063.14 9.74 9.18 -0.0854276186685343 Down 0.146843217540615 MCPH1 microcephalin, isoform D K10605|1|9e-07|56.6|gga:373983|breast cancer type 1 susceptibility protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0000087//M phase of mitotic cell cycle;GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0000087//M phase of mitotic cell cycle;GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0000087//M phase of mitotic cell cycle;GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0000087//M phase of mitotic cell cycle 37206 988.03 7.57 7.355 -0.0415679587309015 Down 0.0819904900277374 wbl windbeutel, isoform B K09586|1|7e-28|124|gga:416882|endoplasmic reticulum protein 29 - - - 39044 1306.00 4.115 4.14 0.00873833707769959 Up 0.0453704926693964 CG4942 CG4942 K03217|1|1e-24|114|tad:TRIADDRAFT_23561|preprotein translocase subunit YidC GO:0031224//intrinsic to membrane GO:0030247//polysaccharide binding GO:0043623//cellular protein complex assembly;GO:0006022;GO:0034613//cellular protein localization 35034 1464.47 0.65 1.01 0.63584366972334 Up 0.187987055871087 CG12620 CG12620, isoform B - - GO:0019212//phosphatase inhibitor activity GO:0007165//signal transduction;GO:0010921//regulation of phosphatase activity 33123 643.00 0.125 0.09 -0.473931188332412 Down 0.0617157574957073 CG10918 CG10918 - - - - 39737 6707.00 9.405 10.675 0.182736220984657 Up 0.260368511425175 l(3)72Ab lethal (3) 72Ab K12854|1|0.0|4078|dme:Dmel_CG5931|pre-mRNA-splicing helicase BRR2 [EC:3.6.1.-] GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0000380//alternative mRNA splicing, via spliceosome 40767 679.00 2.715 1.73 -0.650180160167637 Down 0.314225333509444 CG15597 CG15597 - - - - 37872 713.00 23.09 18.765 -0.299223882887139 Down 0.446638488971074 mRpS17 mitochondrial ribosomal protein S17 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0006810//transport;GO:0010467//gene expression 39647 3450.01 3.175 4.2 0.403632736006594 Up 0.294412891295734 Cep135 Cep135, isoform C K10362|1|1e-18|95.9|cfa:480630|myosin XVIII;K10352|4|1e-16|89.4|smm:Smp_085540.6|myosin heavy chain GO:0005813//centrosome;GO:0005813//centrosome - GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction 39843 2723.00 0.785 0.985 0.327431070564749 Up 0.124686302998283 nxf2 nuclear RNA export factor 2, isoform C - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - GO:0006405//RNA export from nucleus;GO:0006405//RNA export from nucleus 38868 2522.98 8.715 8.215 -0.0852400891756107 Down 0.140503236032228 Snmp2 sensory neuron membrane protein 2, isoform D K06259|1|6e-37|156|mdo:100012876|CD36 antigen GO:0016020//membrane;GO:0016020//membrane GO:0004872//receptor activity;GO:0004872//receptor activity GO:0009987//cellular process;GO:0009987//cellular process 39231 2234.87 53.13 41.055 -0.371968777386958 Down 0.548969753004887 CG43693 CG43693, isoform G K13576|1|1e-10|68.6|dre:436921|sodium-coupled neutral amino acid transporter 3 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 33600 5777.48 3.49 4.965 0.508566681318722 Up 0.364449874521199 CG10019 CG10019, isoform C K08187|1|2e-28|128|nve:NEMVE_v1g88648|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10;K08190|4|6e-26|120|rno:316578|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14;K08184|5|2e-25|118|bta:614573|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 7 - - GO:0006810//transport 35885 2014.00 8.145 8.165 0.0035381870361772 Up 0.0416061286487914 CG30349 CG30349 - - - GO:0048856//anatomical structure development 36718 8273.69 32.41 34.435 0.0874366563739695 Up 0.210210011887465 Khc-73 kinesin heavy chain 73, isoform F K10392|1|0.0|3404|dme:Dmel_CG8183|kinesin family member 1/13/14 GO:0005818//aster;GO:0005875//microtubule associated complex;GO:0005818//aster;GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032559;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032559 GO:0051293//establishment of spindle localization;GO:0051293//establishment of spindle localization 33117 3373.21 159.555 201.655 0.337835358269376 Up 0.562012944128913 slgA sluggish A, isoform N K00318|1|0.0|1242|dme:Dmel_CG1417|proline dehydrogenase [EC:1.5.99.8] GO:0031980;GO:0031980;GO:0031980;GO:0031980;GO:0031980;GO:0031980;GO:0031980;GO:0031980 GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process;GO:0009416//response to light stimulus;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process 34323 1901.51 6.52 6.965 0.0952513883701754 Up 0.13832386738872 CG13126 CG13126, isoform B - - GO:0016741;GO:0046914//transition metal ion binding GO:0010467//gene expression 32234 2246.39 22.915 21.01 -0.125216123701267 Down 0.257165499933959 CG3775 CG3775, isoform B K01389|1|0.0|1189|dme:Dmel_CG3775|neprilysin [EC:3.4.24.11];K01415|2|8e-26|119|dme:Dmel_CG9565|endothelin-converting enzyme [EC:3.4.24.71] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37561 1943.72 21.79 23.06 0.0817263165358649 Up 0.180920618148197 qkr58E-1 quaking related 58E-1, isoform D K13198|1|3e-40|166|oaa:100074961|KH domain-containing, RNA-binding, signal transduction-associated protein 1 GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding GO:0000377 44079 849.00 0.605 2.16 1.83602426488887 Up 0.45667679302602 Ag5r2 antigen 5-related 2 K02330|1|4e-06|52.0|tca:656359|DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-] - - - 12798106 342.00 0.01 0.29 4.85798099512757 Up 0.265024435345397 CG43288 CG43288 - - - - 246581 788.00 200.545 237.315 0.242877294785235 Up 0.470083212257298 GstE9 glutathione S transferase E9 K00799|1|3e-120|431|dme:Dmel_CG17534|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0042221//response to chemical stimulus 32843 1372.00 0.79 1.965 1.3146047540815 Up 0.38809272222956 CG6481 CG6481 - - - - 19835029 1470.00 21.135 20.065 -0.0749529562507975 Down 0.162792233522652 43268 1526.00 5.01 4.445 -0.172627184365438 Down 0.178708228767666 CG5880 CG5880 - - GO:0046914//transition metal ion binding - 31044 2155.00 2.67 3.455 0.371845968700705 Up 0.258024039096553 mus81 mus81 K08991|1|0.0|756|dme:Dmel_CG3026|crossover junction endonuclease MUS81 [EC:3.1.22.-] - - - 19836105 637.00 0.075 0.155 1.04730571477836 Up 0.0978734645357284 31020 1236.64 65.74 67.01 0.0276049507026036 Up 0.108737287016246 CG5254 CG5254, isoform B K03454|1|1e-27|124|nve:NEMVE_v1g237474|mitochondrial carrier protein, MC family - - - 33695 2731.00 102.525 78.84 -0.378976062171093 Down 0.575584467045304 CG3036 CG3036, isoform B K08193|1|0.0|947|dme:Dmel_CG3036|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other GO:0031224//intrinsic to membrane - GO:0015698//inorganic anion transport 37804 1116.00 379.455 263.6 -0.525578434593243 Down 0.656452252014265 Tal Tal K00616|1|0.0|640|dme:Dmel_CG2827|transaldolase [EC:2.2.1.2] GO:0044424//intracellular part GO:0016744 GO:0006098//pentose-phosphate shunt;GO:0051017//actin filament bundle assembly;GO:0060541//respiratory system development;GO:0030855//epithelial cell differentiation;GO:0009653//anatomical structure morphogenesis;GO:0009790//embryo development 41865 1520.00 18.845 21.26 0.173959801866748 Up 0.308942015585788 CG31301 CG31301 - - - - 34879 1523.66 153.185 90.05 -0.766476853061091 Down 0.700667018887862 yellow-c yellow-c, isoform B - - - - 36003 3809.96 302.33 625.395 1.04864354132322 Up 0.742603354906882 trpl transient receptor potential-like, isoform D K13803|1|0.0|1984|dme:Dmel_CG18345|transient-receptor-potential-like protein GO:0016028//rhabdomere;GO:0016021//integral to membrane;GO:0016028//rhabdomere;GO:0016021//integral to membrane;GO:0016028//rhabdomere;GO:0016021//integral to membrane GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding GO:0009314//response to radiation;GO:0046903//secretion;GO:0019932//second-messenger-mediated signaling;GO:0070838//divalent metal ion transport;GO:0009314//response to radiation;GO:0046903//secretion;GO:0019932//second-messenger-mediated signaling;GO:0070838//divalent metal ion transport;GO:0009314//response to radiation;GO:0046903//secretion;GO:0019932//second-messenger-mediated signaling;GO:0070838//divalent metal ion transport 19834883 299.00 0.01 1.31 7.03342300153745 Up 0.564984810460969 40408 463.00 0.01 0.125 3.64385618977472 Up 0.151697265882974 Cpr78E cuticular protein 78E - - GO:0005198//structural molecule activity - 31806 1307.00 6.735 6.76 0.00534530081988121 Up 0.0453704926693964 Ogg1 Ogg1 K03660|1|0.0|686|dme:Dmel_CG1795|N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0000702//oxidized base lesion DNA N-glycosylase activity;GO:0016835//carbon-oxygen lyase activity GO:0006281//DNA repair 36269 1295.00 0.06 0.07 0.222392421336448 Up 0.0461960110949676 cuff cutoff - GO:0044444//cytoplasmic part - GO:0003002//regionalization;GO:0051276//chromosome organization;GO:0007293//germarium-derived egg chamber formation 41885 1595.00 83.185 27.555 -1.59400927647711 Down 0.761920486065249 Act88F actin 88F K05692|1|0.0|762|dya:Dyak_GE24312|actin beta/gamma 1 - - - 318991 1068.00 2.595 2.485 -0.0624886867955946 Down 0.0690463611147801 Ada1-1 transcriptional adaptor 1-1, isoform B K11317|1|2e-149|528|dme:Dmel_CG31866|transcriptional adapter 1-like protein - GO:0003676//nucleic acid binding - 33937 1587.00 0.275 0.425 0.628031222613042 Up 0.11781798969753 cort cortex, isoform B K03364|1|8e-13|75.5|api:100168994|cell division cycle 20-like protein 1, cofactor of APC complex;K03363|2|4e-12|73.2|cin:100179065|cell division cycle 20, cofactor of APC complex;K12602|5|5e-10|66.2|cin:100182087|WD repeat-containing protein 61 GO:0044424//intracellular part GO:0032403//protein complex binding GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0001775//cell activation;GO:0007143//female meiosis;GO:0051441;GO:0007275//multicellular organismal development 39549 1352.00 2.83 2.755 -0.0387497342607248 Down 0.0603288865407476 CG17359 CG17359 K09228|1|5e-33|142|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 36024 906.00 0.975 0.925 -0.0759488532332988 Down 0.0567956676793026 CG12744 CG12744, isoform B K09299|1|2e-07|56.6|dgr:Dgri_GH14214|zinc finger homeobox protein 1;K09228|2|6e-07|54.7|cfa:484968|KRAB domain-containing zinc finger protein;K10498|3|8e-07|54.3|oaa:100089499|zinc finger and BTB domain-containing protein 11 GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 37855 500.00 2.68 1.27 -1.07740450368561 Down 0.407707040021133 CG13564 CG13564 - - - - 34545 1623.00 0.87 1.545 0.828519532055646 Up 0.276449610355303 Gr32a gustatory receptor 32a K08471|1|0.0|861|dme:Dmel_CG14916|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 36184 953.00 0.125 0.14 0.16349873228288 Up 0.0504556861709153 CG13226 CG13226 - - - - 31002 5950.56 164.665 161.73 -0.0259466234355666 Down 0.113492273147537 Appl beta amyloid protein precursor-like, isoform F K04520|1|7e-89|330|ame:551733|amyloid beta (A4) protein - - - 35026 16318.88 12.775 15.785 0.305230969488002 Up 0.417084929335623 tweek tweek, isoform K - - - - 12798364 1078.00 0.36 0.925 1.361456459074 Up 0.27734117025492 CG43168 CG43168 - - - - 37886 3426.00 12.06 13.465 0.158984322601587 Up 0.257660810989301 nvy nervy, isoform D K10053|1|3e-54|214|bfo:BRAFLDRAFT_201173|runt-related transcription factor 1; translocated to, 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent 42951 1837.00 0.595 0.31 -0.940621452921068 Down 0.177849689605072 CG13634 CG13634 - - - - 45268 1396.00 242.725 177.875 -0.448458952967362 Down 0.623332452780346 cathD cathD K01379|1|0.0|744|dme:Dmel_CG1548|cathepsin D [EC:3.4.23.5] GO:0000323//lytic vacuole;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0048102//autophagic cell death 3885642 1163.00 0.04 0.115 1.52356195605701 Up 0.0933166028265751 CG33966 CG33966 K10693|1|2e-18|93.2|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K01104|2|8e-06|51.6|xla:379146|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part - GO:0051234//establishment of localization 36731 659.00 247.385 234.57 -0.0767395125447636 Down 0.221602166160349 Vha14-1 vacuolar H[+] ATPase 14kD subunit 1 K02151|1|9e-67|252|dya:Dyak_GE14140|V-type H+-transporting ATPase subunit F [EC:3.6.3.14] GO:0033176 GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 14462633 1952.00 12.245 2.9 -2.07806796854904 Down 0.710771364416854 14462761 836.00 1.61 2.08 0.369522840026475 Up 0.198421608770308 CG43779 CG43779 - - - - 19835790 2592.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 318599 1450.00 4.055 3.855 -0.0729710543022385 Down 0.0883304715361247 CG31125 CG31125 - - - - 43551 2879.49 5 7.02 0.489542935642474 Up 0.410381719719984 Takr99D Tachykinin-like receptor at 99D, isoform C K04225|1|0.0|997|dsi:Dsim_GD17519|tachykinin receptor, invertebrate GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 43582 1140.56 482.565 492.9 0.0305716990185553 Up 0.11643111874257 Tpi triose phosphate isomerase, isoform C K01803|1|3e-149|528|dme:Dmel_CG2171|triosephosphate isomerase (TIM) [EC:5.3.1.1] - GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0006007//glucose catabolic process;GO:0006631//fatty acid metabolic process;GO:0003008;GO:0010259//multicellular organismal aging;GO:0009605//response to external stimulus;GO:0006007//glucose catabolic process;GO:0006631//fatty acid metabolic process;GO:0003008;GO:0010259//multicellular organismal aging;GO:0009605//response to external stimulus;GO:0006007//glucose catabolic process;GO:0006631//fatty acid metabolic process;GO:0003008;GO:0010259//multicellular organismal aging;GO:0009605//response to external stimulus 32256 5270.12 13.605 16.675 0.293549804822268 Up 0.40882974507991 hep hemipterous, isoform F K04431|1|0.0|771|dme:Dmel_CG4353|mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] GO:0043005//neuron projection;GO:0043005//neuron projection GO:0004708//MAP kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004708//MAP kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0009611//response to wounding;GO:0022617//extracellular matrix disassembly;GO:0006582//melanin metabolic process;GO:0055088//lipid homeostasis;GO:0006355//regulation of transcription, DNA-dependent;GO:0030035//microspike assembly;GO:0010259//multicellular organismal aging;GO:0007297//ovarian follicle cell migration;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0043406//positive regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0048588//developmental cell growth;GO:0007560//imaginal disc morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0002682//regulation of immune system process;GO:0000165//MAPK cascade;GO:0009611//response to wounding;GO:0022617//extracellular matrix disassembly;GO:0006582//melanin metabolic process;GO:0055088//lipid homeostasis;GO:0006355//regulation of transcription, DNA-dependent;GO:0030035//microspike assembly;GO:0010259//multicellular organismal aging;GO:0007297//ovarian follicle cell migration;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0043406//positive regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0048588//developmental cell growth;GO:0007560//imaginal disc morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0002682//regulation of immune system process;GO:0000165//MAPK cascade 40724 2397.11 21.34 17.905 -0.2531976575039 Down 0.392880729097873 CG2023 CG2023, isoform B K08497|1|1e-106|385|dpo:Dpse_GA15191|protein transport protein SEC20 - - - 34853 406.52 36.405 19.53 -0.898444659985498 Down 0.680524369303923 CG15282 CG15282, isoform C - - - - 33105 1404.00 131.15 82.595 -0.667091453697098 Down 0.678080834764232 Pros45 regulatory particle triple-A ATPase 6 K03066|1|0.0|729|dme:Dmel_CG1489|26S proteasome regulatory subunit T6 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0005838//proteasome regulatory particle GO:0017111//nucleoside-triphosphatase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0032559 GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process 35369 2158.20 15.57 19.635 0.33465865358736 Up 0.456874917448157 CG9265 CG9265, isoform D K11151|1|2e-48|194|cfa:486998|retinol dehydrogenase 10 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 31244 1795.17 6.885 7.825 0.184634097685016 Up 0.229362039360719 Tsp3A tetraspanin 3A, isoform B K10303|1|1e-45|184|dre:324950|F-box protein 23 - - - 3772375 2037.00 0.035 0.035 0 - 0.0382380134724607 CG32270 CG32270 K01312|1|3e-41|170|dme:Dmel_CG18211|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36235 767.00 1.955 1.01 -0.952813314555558 Down 0.331363096024303 CG7763 CG7763, isoform B K10065|1|5e-10|64.7|gga:420281|collectin sub-family member 10;K06560|2|6e-10|64.3|cin:100186027|mannose receptor, C type - - - 14462445 1964.44 1.94 1.96 0.0147970019280805 Up 0.0432901862369568 CG43675 CG43675, isoform D K12163|1|2e-11|71.6|tca:663257|AN1-type zinc finger and ubiquitin domain-containing protein 1 - GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 326229 2385.00 6.68 9.915 0.569764669754796 Up 0.49316470743627 CG32669 CG32669 K03307|1|7e-96|352|ptr:467108|solute:Na+ symporter, SSS family GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0015370//solute:sodium symporter activity GO:0050658//RNA transport;GO:0030001//metal ion transport 19835960 342.00 0.905 0.15 -2.59295529147469 Down 0.353123761722362 38415 1636.00 16.59 20.37 0.296132094010025 Up 0.434817065116893 CG14969 CG14969 - - - - 19835443 796.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 38058 2060.96 14.485 11.615 -0.318570530461596 Down 0.417349095231806 mth methuselah, isoform E K04599|1|0.0|978|dme:Dmel_CG6936|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0010259//multicellular organismal aging;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0006887//exocytosis;GO:0023060;GO:0010259//multicellular organismal aging;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0006887//exocytosis;GO:0023060 43275 5673.69 0.985 0.545 -0.85386749467945 Down 0.22173424910844 Ser serrate, isoform B K06052|1|0.0|2770|dme:Dmel_CG6127|jagged GO:0031224//intrinsic to membrane GO:0046872//metal ion binding GO:0007166//cell surface receptor signaling pathway;GO:0032501//multicellular organismal process;GO:0009987//cellular process 42476 3138.62 7.8 7.58 -0.041276275578519 Down 0.0830141328754458 CG5621 CG5621, isoform D K05313|1|0.0|763|dme:Dmel_CG31201|glutamate receptor, ionotropic, invertebrate GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport 42074 2170.00 1.055 1.365 0.371657952212667 Up 0.160018491612733 CG5265 CG5265 K00624|1|0.0|1290|dme:Dmel_CG5265|carnitine O-acetyltransferase [EC:2.3.1.7] - - - 31218 1201.54 1.265 0.77 -0.716207033999409 Down 0.230319640734381 CG14050 CG14050, isoform B - - - - 32240 1303.12 20.67 20.595 -0.00524426255719091 Down 0.0526350548144235 CG4407 CG4407, isoform B K00953|1|6e-180|630|dme:Dmel_CG4407|FAD synthetase [EC:2.7.7.2] - GO:0003824//catalytic activity;GO:0003824//catalytic activity - 43589 2063.75 1.02 1.68 0.719892080807265 Up 0.265420684189671 CG15530 CG15530, isoform C - - - - 39554 1205.85 109.34 101.545 -0.106702076494105 Down 0.272982432967904 endos endosulfine, isoform F - - - GO:0048878//chemical homeostasis;GO:0000278//mitotic cell cycle;GO:0007292//female gamete generation;GO:0031667//response to nutrient levels;GO:0051726//regulation of cell cycle;GO:0048878//chemical homeostasis;GO:0000278//mitotic cell cycle;GO:0007292//female gamete generation;GO:0031667//response to nutrient levels;GO:0051726//regulation of cell cycle 317846 587.00 0.01 0.16 4 Up 0.178939373926826 Vha16-3 vacuolar H[+] ATPase 16kD subunit 3, isoform B K02155|1|5e-67|253|dsi:Dsim_GD14307|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] GO:0031224//intrinsic to membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0031224//intrinsic to membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 38463 1089.00 296.065 346.875 0.228501917242827 Up 0.462422401267996 CG10863 CG10863 K00011|1|0.0|655|dme:Dmel_CG10863|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity GO:0008152//metabolic process 38542 701.80 36.69 31.21 -0.233378547329332 Down 0.410579844142121 CG15019 CG15019, isoform B - - - - 19836133 1602.00 28.075 37.66 0.423746977326265 Up 0.560097741381588 34319 2717.00 0.425 0.225 -0.917537839808027 Down 0.146975300488707 CG42366 CG42366, isoform B K08829|1|2e-131|470|ame:409409|male germ cell-associated kinase [EC:2.7.11.22];K08828|4|3e-122|439|ecb:100056645|intestinal cell (MAK-like) kinase [EC:2.7.11.22] - GO:0004672//protein kinase activity;GO:0032559;GO:0005198//structural molecule activity GO:0006464//cellular protein modification process 36546 1433.16 560.005 357.74 -0.646528268835551 Down 0.687623827763836 Cp1 cysteine proteinase-1, isoform E K01365|1|0.0|644|dme:Dmel_CG6692|cathepsin L [EC:3.4.22.15] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole;GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0032501//multicellular organismal process;GO:0048869//cellular developmental process;GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0032501//multicellular organismal process;GO:0048869//cellular developmental process;GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0032501//multicellular organismal process;GO:0048869//cellular developmental process;GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0032501//multicellular organismal process;GO:0048869//cellular developmental process 14462344 738.00 3.18 4.805 0.595509665489395 Up 0.390536256769251 CG43676 CG43676 - - - - 32633 1499.00 0.28 0.66 1.23703919730085 Up 0.220446440364549 CG9777 CG9777 K04514|1|5e-110|398|dse:Dsec_GM13385|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - GO:0005488//binding;GO:0016301//kinase activity - 32471 1646.93 71.4 47.835 -0.577857475943045 Down 0.646479989433364 Ahcy13 adenosylhomocysteinase at 13, isoform C K01251|1|0.0|863|dme:Dmel_CG11654|adenosylhomocysteinase [EC:3.3.1.1] - GO:0016802 GO:0044237//cellular metabolic process 318170 1335.00 0.375 0.355 -0.0790715709911988 Down 0.0463611147800819 CG32720 CG32720 - - - - 40468 2316.00 30.335 35.52 0.227648270317189 Up 0.407541936336019 laza lazaro K01080|1|2e-148|526|dme:Dmel_CG11440|phosphatidate phosphatase [EC:3.1.3.4] GO:0044464//cell part GO:0016791//phosphatase activity GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0009416//response to light stimulus;GO:0009266//response to temperature stimulus 5740196 844.00 1.25 1.345 0.105678077894537 Up 0.0709285431250826 CG34292 CG34292 - - - - 45816 6389.62 46.06 61.51 0.417306564810765 Up 0.581131950865143 onecut onecut, isoform B K08026|1|2e-65|252|xtr:100101763|one cut domain, family member 1, hepatocyte nuclear factor 6 - - - 35383 993.58 15.055 18.09 0.264949699896564 Up 0.389314489499406 CG9249 CG9249, isoform B K00591|1|6e-168|589|dme:Dmel_CG9249|hexaprenyldihydroxybenzoate methyltransferase [EC:2.1.1.114] - GO:0030580//quinone cofactor methyltransferase activity;GO:0030580//quinone cofactor methyltransferase activity GO:0006743//ubiquinone metabolic process;GO:0006743//ubiquinone metabolic process 32514 1347.00 14.265 15.44 0.114193005686361 Up 0.206247523444723 Arp6 Actin-related protein 6 K11662|1|0.0|810|dme:Dmel_CG11678|actin-related protein 6 GO:0015629//actin cytoskeleton GO:0005488//binding GO:0006996//organelle organization 37263 2011.00 1.605 2.385 0.571415968883208 Up 0.276614714040417 CG15128 CG15128 - - - - 12798184 1119.00 0.38 1.075 1.50026533614587 Up 0.312277110025096 CG43050 CG43050 - - - - 34352 901.72 870.685 853.12 -0.0294021835324105 Down 0.117223616431119 RpL7 ribosomal protein L7, isoform B K02937|1|3e-131|467|dme:Dmel_CG4897|large subunit ribosomal protein L7e GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 37581 774.05 39.86 38.955 -0.0331331954394944 Down 0.105237088891824 Vps20 vacuolar protein sorting 20, isoform C K12195|1|5e-76|283|dse:Dsec_GM15925|charged multivesicular body protein 6 - - GO:0006810//transport 32838 3938.07 8.14 8.48 0.0590354702969521 Up 0.106987187954035 Wnt5 Wnt oncogene analog 5, isoform B K00444|1|2e-118|427|cqu:CpipJ_CPIJ015288|wingless-type MMTV integration site family, member 5 GO:0031012//extracellular matrix GO:0060089;GO:0005102//receptor binding GO:0007411//axon guidance;GO:0003002//regionalization;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0048588//developmental cell growth;GO:0007431//salivary gland development 19836064 809.00 0.395 0.755 0.934623991147976 Up 0.204101175538238 38180 1697.00 45.51 60.33 0.406691996058319 Up 0.575023114515916 Cct2 CTP:phosphocholine cytidylyltransferase 2 K00968|1|0.0|730|dme:Dmel_CG18330|choline-phosphate cytidylyltransferase [EC:2.7.7.15] GO:0043231//intracellular membrane-bounded organelle GO:0070567 GO:0016192//vesicle-mediated transport;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0046470//phosphatidylcholine metabolic process;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0001736//establishment of planar polarity 41176 1263.00 42.37 28.305 -0.581986205042289 Down 0.6267335886937 CG18542 CG18542 - - GO:0016407//acetyltransferase activity - 35404 2760.94 0.475 0.485 0.0300572338561799 Up 0.0416391493858143 dimm dimmed, isoform B K08040|1|3e-112|405|dpo:Dpse_GA21247|class B basic helix-loop-helix protein 8;K08898|2|2e-22|107|tgu:100218381|lemur tyrosine kinase 2 [EC:2.7.10.1] GO:0043231//intracellular membrane-bounded organelle - GO:0006355//regulation of transcription, DNA-dependent;GO:0046879//hormone secretion;GO:0002790//peptide secretion 35137 1680.00 5.77 5.125 -0.171019314252674 Down 0.190364548936732 CG17324 CG17324 K00699|1|1e-125|450|dme:Dmel_CG17323|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups GO:0002118//aggressive behavior 40345 3909.96 16.235 22.385 0.463424933617456 Up 0.542959978866728 Eip78C Ecdysone-induced protein 78C, isoform E K08701|1|0.0|1003|dme:Dmel_CG18023|nuclear receptor subfamily 1 group D member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0010468//regulation of gene expression;GO:0009791//post-embryonic development;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0009791//post-embryonic development;GO:0006351//transcription, DNA-dependent 3772154 340.00 10.805 31.23 1.53123349716107 Up 0.731904636111478 CG6555 accessory gland-specific peptide 33A - - - - 40741 1170.53 6.62 8.78 0.407389722728141 Up 0.404834235900145 CG11459 CG11459, isoform B K01365|1|0.0|662|dme:Dmel_CG11459|cathepsin L [EC:3.4.22.15] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41680 1737.00 12.82 10.16 -0.335495859846575 Down 0.41566503764364 Adgf-C adenosine deaminase-related growth factor C K01488|1|1e-119|430|dvi:Dvir_GJ14281|adenosine deaminase [EC:3.5.4.4] - - - 37750 783.00 22.265 18.05 -0.30277877466837 Down 0.444525161801611 mRpL43 mitochondrial ribosomal protein L43 K03946|1|1e-26|120|cel:C25A1.13|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2 [EC:1.6.5.3 1.6.99.3] GO:0000315//organellar large ribosomal subunit - GO:0010467//gene expression 41396 1200.94 4.87 5.62 0.206648358138584 Up 0.217045304451195 CG6813 CG6813, isoform D K09228|1|1e-24|114|hsa:148198|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 33552 5865.79 28.72 32.62 0.183701032888833 Up 0.34708096684718 CG34394 CG34394, isoform H - - - - 34378 8431.00 50.205 54.27 0.112323856934711 Up 0.261161009113723 CG5604 CG5604 K12231|1|0.0|5135|dme:Dmel_CG5604|E3 ubiquitin-protein ligase HECTD1 [EC:6.3.2.19] GO:0044464//cell part GO:0019787//small conjugating protein ligase activity;GO:0043169//cation binding GO:0032446//protein modification by small protein conjugation 34530 4315.76 3.5 3.145 -0.15429490495304 Down 0.140668339717342 Samuel SAM-motif ubiquitously expressed punctatedly localized protein, isoform D K11456|1|5e-11|71.2|dme:Dmel_CG18412|polyhomeotic-like protein 1;K11457|5|3e-09|65.1|spu:585003|polyhomeotic-like protein 2 - - - 12798004 475.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 CG43406 CG43406, isoform B - - - - 19835691 1377.00 0.035 0.08 1.1926450779424 Up 0.0725795799762251 8674008 538.00 5.125 3.97 -0.368412997249851 Down 0.309272222956016 Sfp51E seminal fluid protein 51E - - - - 3771916 1981.86 1.065 1 -0.0908534304511135 Down 0.0601637828556333 Gr64e gustatory receptor 64e, isoform B K08471|1|0.0|862|dme:Dmel_CG32258|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity - 33404 1114.00 0.385 0.77 1 Up 0.215262184651961 Tengl3 testis EndoG-Like 3 K01173|1|1e-17|90.5|aga:AgaP_AGAP007845|endonuclease [EC:3.1.30.-] - GO:0004519//endonuclease activity;GO:0043169//cation binding - 19835371 1353.00 1.845 1.895 0.0385770321106955 Up 0.0540219257693832 38511 961.00 0.245 0.14 -0.807354922057604 Down 0.106789063531898 Cpr64Ad cuticular protein 64Ad - - GO:0005198//structural molecule activity - 41095 1736.39 48.5 49.12 0.0183258134083271 Up 0.0849293356227711 D1 D1 chromosomal protein, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding - 39393 1740.00 1.465 1.06 -0.466836399859048 Down 0.190034341566504 Est-P esterase P K01044|1|0.0|1091|dme:Dmel_CG17148|carboxylesterase [EC:3.1.1.1];K03927|3|2e-55|217|api:100162163|carboxylesterase type B [EC:3.1.1.1] - GO:0016788//hydrolase activity, acting on ester bonds - 34358 4176.99 61.545 62.475 0.0216373413603748 Up 0.0877691190067362 Npc1a Niemann-Pick type C-1a, isoform G K12385|1|0.0|2422|dme:Dmel_CG5722|Niemann-Pick C1 protein GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0015918//sterol transport;GO:0015918//sterol transport;GO:0015918//sterol transport;GO:0015918//sterol transport 246602 621.99 456.66 428.205 -0.0928187842896857 Down 0.244848765024435 CG30415 CG30415, isoform B - - - - 35663 574.00 0.425 0.87 1.03355255971103 Up 0.231871615374455 CG11145 CG11145 - - - - 37701 4537.00 1.865 1.8 -0.0511787239255634 Down 0.0588099326376965 Ice1 interacts with the C terminus of ELL 1 - - - - 19836024 768.00 0.115 0.41 1.83399004856107 Up 0.205851274600449 32026 1305.00 31.63 31.725 0.00432660821107477 Up 0.0452714304583278 v vermilion K00453|1|0.0|717|dme:Dmel_CG2155|tryptophan 2,3-dioxygenase [EC:1.13.11.11] - GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding GO:0006569//tryptophan catabolic process;GO:0006726//eye pigment biosynthetic process 37470 2260.92 10.745 11.355 0.0796622232791043 Up 0.145654471007793 CG9865 CG9865, isoform B K05284|1|0.0|845|dme:Dmel_CG9865|phosphatidylinositol glycan, class M [EC:2.4.1.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups GO:0006497//protein lipidation;GO:0006497//protein lipidation 43062 1445.00 0.215 0.34 0.661198086548241 Up 0.107284374587241 CG31087 CG31087, isoform B - - - - 38529 858.00 136.185 97.755 -0.478325406692906 Down 0.627592127856294 CG15012 CG15012 - - - - 14462595 9258.65 0.37 0.5 0.434402824145775 Up 0.106623959846784 42720 672.00 0.01 0.37 5.20945336562895 Up 0.306333377360983 CG13837 CG13837 - - GO:0030247//polysaccharide binding GO:0006022 32094 1432.00 11.96 10.995 -0.121369785343137 Down 0.199940562673359 CG1749 CG1749 K12164|1|0.0|727|dme:Dmel_CG1749|ubiquitin-like modifier-activating enzyme 5 - GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0043169//cation binding;GO:0032559 - 19835417 500.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 5740440 1100.00 0.25 0.33 0.400537929583729 Up 0.0869105798441421 CG34190 CG34190 K02155|1|2e-16|84.0|dan:Dana_GF13441|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] GO:0044425//membrane part - GO:0006810//transport 7354471 2026.01 72.85 56.585 -0.364509309580115 Down 0.554979527143046 CG42240 CG42240, isoform C - - - - 38657 5102.00 2.96 3.265 0.141485815917481 Up 0.125610883634923 vn vein, isoform C K05456|1|2e-13|79.3|rno:432361|neuregulin 2;K05455|5|4e-08|61.6|dre:796461|neuregulin 1 - - - 40916 1361.00 32.89 37.625 0.194042573699024 Up 0.367025492008982 pyd3 pyd3 K01431|1|0.0|796|dme:Dmel_CG3027|beta-ureidopropionase [EC:3.5.1.6] - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0019856//pyrimidine nucleobase biosynthetic process 8673994 1818.00 0.04 2.05 5.67948009950545 Up 0.620327565711267 Ir75b ionotropic receptor 75b K05202|1|2e-09|64.3|bfo:BRAFLDRAFT_128813|glutamate receptor, ionotropic, kainate 2;K05200|2|1e-07|58.5|gga:396137|glutamate receptor, ionotropic, AMPA 4 GO:0016020//membrane GO:0005216//ion channel activity;GO:0004872//receptor activity GO:0006810//transport 36508 1065.00 38.48 28.13 -0.451999246455342 Down 0.575683529256373 Roe1 Roe1 K03687|1|2e-116|418|dme:Dmel_CG6155|molecular chaperone GrpE GO:0031980 GO:0030554//adenyl nucleotide binding;GO:0042802//identical protein binding GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion 41403 640.00 29.16 3.89 -2.90614865934075 Down 0.788502179368644 CG14715 CG14715 K09569|1|2e-64|244|dme:Dmel_CG14715|FK506-binding protein 2 [EC:5.2.1.8] - GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 32225 14438.49 5.43 6.19 0.188987211409903 Up 0.213313961167613 Smr smrter, isoform G K04650|1|8e-59|231|spu:588549|nuclear receptor co-repressor 1;K06065|5|1e-57|227|tgu:100219945|nuclear receptor co-repressor 2 - GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0050794//regulation of cellular process;GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0050794//regulation of cellular process;GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0050794//regulation of cellular process 326208 2694.00 5.16 5.74 0.153679671252434 Up 0.175868445383701 CG32344 CG32344 K01529|1|0.0|1484|dme:Dmel_CG32344| [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0003724//RNA helicase activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559 - 38298 3544.00 6.39 6.175 -0.0493767944749546 Down 0.0863162065777308 DmsR-1 myosuppressin receptor 1, isoform B K04233|1|3e-08|61.6|cel:ZK455.3|galanin receptor, invertebrate;K08428|2|8e-07|56.6|cfa:489988|G protein-coupled receptor 139;K04194|5|1e-06|55.8|gga:422801|cholecystokinin A receptor GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0006937//regulation of muscle contraction;GO:0007166//cell surface receptor signaling pathway 19835361 1371.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 41837 1754.09 5.655 5.48 -0.0453511310292934 Down 0.0784572711662924 Art3 arginine methyltransferase 3, isoform B K11436|1|0.0|947|dme:Dmel_CG6563|protein arginine N-methyltransferase 3 [EC:2.1.1.-] - - - 38396 1684.00 14.81 14.405 -0.0400019801289775 Down 0.102595429929996 CG12034 CG12034 K12351|1|0.0|803|dme:Dmel_CG12034|sphingomyelin phosphodiesterase 2 [EC:3.1.4.12] GO:0043231//intracellular membrane-bounded organelle GO:0004620//phospholipase activity GO:0006644//phospholipid metabolic process;GO:0006672//ceramide metabolic process 41762 587.00 0.01 0.19 4.24792751344359 Up 0.201558578787479 CG14850 CG14850 - - - - 36579 3183.67 29.985 35.97 0.262553186669596 Up 0.439208823140933 CG8485 CG8485, isoform C K08802|1|0.0|1474|dme:Dmel_CG8485|SNF related kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 33686 2759.58 60.27 65.335 0.116415986689826 Up 0.281204596486594 CG2950 mextli, isoform G - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0044260;GO:0044260;GO:0044260;GO:0044260 37395 2319.00 19.455 22.825 0.230473879898729 Up 0.378714832915071 CG4030 Rabaptin-5 K12480|1|8e-105|381|tca:660676|Rab GTPase-binding effector protein 1 - - - 43471 3479.00 12.29 13.555 0.14134019746505 Up 0.236923788138951 CG2321 CG2321, isoform B - - - - 3772044 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 30980 2038.00 0.75 0.045 -4.05889368905357 Down 0.374917448157443 y yellow - - - - 5740828 1994.00 100.21 105.63 0.0759931501449393 Up 0.21374323074891 33395 1963.00 0.025 0.07 1.48542682717024 Up 0.0803064324395721 CG31668 CG31668 K03307|1|6e-96|351|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0016020//membrane - GO:0006811//ion transport 33898 2327.54 35.445 29.865 -0.247126408253344 Down 0.427255316338661 CG9527 CG9527, isoform D K00232|1|0.0|1409|dme:Dmel_CG9527|acyl-CoA oxidase [EC:1.3.3.6] GO:0042579//microbody;GO:0042579//microbody GO:0030554//adenyl nucleotide binding;GO:0016634;GO:0030554//adenyl nucleotide binding;GO:0016634 GO:0009062//fatty acid catabolic process;GO:0006909//phagocytosis;GO:0009062//fatty acid catabolic process;GO:0006909//phagocytosis 33459 1438.02 1.175 1.53 0.380870896127652 Up 0.171047417778365 CG9961 CG9961, isoform B K00927|1|0.0|848|dme:Dmel_CG9961|phosphoglycerate kinase [EC:2.7.2.3] GO:0044424//intracellular part GO:0016301//kinase activity GO:0006007//glucose catabolic process 41689 1117.00 15.78 17.305 0.133091736151989 Up 0.241876898692379 CG9288 CG9288 - - - - 13084069 637.90 37.24 47.17 0.341016527970803 Up 0.525326905296526 CG43346 CG43346, isoform C - - - - 39255 3483.20 124.76 153.28 0.297014008362028 Up 0.526548672566372 CG42575 CG42575, isoform B K03306|1|0.0|1132|dme:Dmel_CG42575|inorganic phosphate transporter, PiT family GO:0044464//cell part GO:0015291//secondary active transmembrane transporter activity GO:0015698//inorganic anion transport 19834763 501.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 2768732 751.00 10.145 10.27 0.0176673165615362 Up 0.0611544049663188 CG33228 CG33228, isoform C - - - - 31292 5116.04 8.135 8.58 0.076835301827018 Up 0.129375247655528 kirre kin of irre, isoform G K12567|1|6e-16|87.0|rno:84015|titin [EC:2.7.11.1] - - - 36095 2982.00 0.06 0.045 -0.415037499278844 Down 0.0547483819838859 Ir47a ionotropic receptor 47a - - - - 34227 644.00 0.995 1.275 0.357728816315209 Up 0.150508519350152 CG9568 CG9568 - - - - 42625 1471.00 1.48 1.055 -0.488354176921765 Down 0.198223484348171 CG5379 CG5379, isoform B K01672|1|2e-180|631|dme:Dmel_CG5379|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 12798281 777.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 CG43125 CG43125 - - - - 38746 3161.75 197.51 131.155 -0.590652891019037 Down 0.667217012283714 ple pale, isoform C K00501|1|0.0|1039|dsi:Dsim_GD13115|tyrosine 3-monooxygenase [EC:1.14.16.2] - GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding GO:0007626//locomotory behavior;GO:0006520//cellular amino acid metabolic process;GO:0042069//regulation of catecholamine metabolic process;GO:0042417//dopamine metabolic process;GO:0007619//courtship behavior;GO:0032502//developmental process;GO:0007626//locomotory behavior;GO:0006520//cellular amino acid metabolic process;GO:0042069//regulation of catecholamine metabolic process;GO:0042417//dopamine metabolic process;GO:0007619//courtship behavior;GO:0032502//developmental process 39744 5340.11 16.055 16.7 0.0568254376356448 Up 0.133998150838727 brm brahma, isoform F K11647|1|0.0|2404|dse:Dsec_GM24456|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.1.-] GO:0070603//SWI/SNF superfamily-type complex;GO:0070603//SWI/SNF superfamily-type complex;GO:0070603//SWI/SNF superfamily-type complex;GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled GO:0006909//phagocytosis;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0035468;GO:0003002//regionalization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006338//chromatin remodeling;GO:0007292//female gamete generation;GO:0002376//immune system process;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0006909//phagocytosis;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0035468;GO:0003002//regionalization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006338//chromatin remodeling;GO:0007292//female gamete generation;GO:0002376//immune system process;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0006909//phagocytosis;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0035468;GO:0003002//regionalization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006338//chromatin remodeling;GO:0007292//female gamete generation;GO:0002376//immune system process;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0006909//phagocytosis;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0035468;GO:0003002//regionalization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006338//chromatin remodeling;GO:0007292//female gamete generation;GO:0002376//immune system process;GO:0007476//imaginal disc-derived wing morphogenesis 43715 3229.00 0.225 0.055 -2.03242147769238 Down 0.152093514727249 mey morpheyus, isoform B - - - - 40336 1609.00 8.05 11.18 0.473859499841211 Up 0.471106855105006 park parkin, isoform C K04556|1|0.0|1031|dme:Dmel_CG10523|parkin [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity GO:0043409//negative regulation of MAPK cascade;GO:0016567//protein ubiquitination;GO:0048232//male gamete generation;GO:0007005//mitochondrion organization;GO:0006950//response to stress;GO:0043409//negative regulation of MAPK cascade;GO:0016567//protein ubiquitination;GO:0048232//male gamete generation;GO:0007005//mitochondrion organization;GO:0006950//response to stress 33865 1602.00 4.07 4.83 0.246994394569526 Up 0.227711002509576 WDR79 WD repeat domain 79 homolog, isoform C - - - - 37412 1081.00 6.875 8.685 0.337166135411008 Up 0.364978206313565 CG9437 hinge1 - - - - 5740370 718.00 0.28 0.495 0.822001698022005 Up 0.147437590807027 CG34307 CG34307 - - - - 41319 3109.86 8.26 10.485 0.344113174677147 Up 0.392088231409325 CG6621 CG6621, isoform B - - - - 34681 1461.00 19.46 25.42 0.385452320223848 Up 0.516246202615242 spict spichthyin, isoform B - - - GO:0008582//regulation of synaptic growth at neuromuscular junction 3771872 639.53 1.585 2.575 0.700089591931174 Up 0.320235107647603 Hsp67Bb heat shock gene 67Bb, isoform D K01010|1|1e-29|130|dme:Dmel_CG12279|thiosulfate sulfurtransferase [EC:2.8.1.1] - GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity GO:0006457//protein folding;GO:0006950//response to stress;GO:0010259//multicellular organismal aging 39863 2187.00 0.795 1.125 0.500898235932682 Up 0.173061682736759 CG13032 CG13032 K10352|1|4e-16|87.0|oaa:100086990|myosin heavy chain - - - 39899 4099.84 215.465 243.59 0.177001370229271 Up 0.396843217540616 Nc73EF neural conserved at 73EF, isoform J K00164|1|0.0|1981|dsi:Dsim_GD14681|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration 35917 1670.00 9.3 9.51 0.0322146248651695 Up 0.0771364416853784 Dbp45A DEAD box protein 45A K01529|1|2e-74|280|nve:NEMVE_v1g192845| [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0000380//alternative mRNA splicing, via spliceosome 39894 1792.00 0.935 0.565 -0.726715497472449 Down 0.196110157178708 CG13023 CG13023, isoform B - - - - 37156 2418.00 10.57 11.85 0.164911682402939 Up 0.250429269581297 CG15087 CG15087 - - - - 3771959 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33806 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 36825 2393.00 4.585 4.705 0.0372729891334825 Up 0.0677255316338661 CG4282 CG4282 K09228|1|7e-34|145|mmu:69930|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 38998 649.00 1.035 1.215 0.231325546106456 Up 0.107218333113195 Cp18 chorion protein 18 - - - - 41398 4560.50 30.775 30.035 -0.0351141928453498 Down 0.116992471271959 Csk C-terminal Src kinase, isoform L K05728|1|0.0|925|dme:Dmel_CG42317|c-src tyrosine kinase [EC:2.7.10.2] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0040008//regulation of growth;GO:0012501//programmed cell death;GO:0023060;GO:0001894//tissue homeostasis;GO:0023033;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0034331;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0012501//programmed cell death;GO:0023060;GO:0001894//tissue homeostasis;GO:0023033;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0034331;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0012501//programmed cell death;GO:0023060;GO:0001894//tissue homeostasis;GO:0023033;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0034331;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0012501//programmed cell death;GO:0023060;GO:0001894//tissue homeostasis;GO:0023033;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0034331;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0012501//programmed cell death;GO:0023060;GO:0001894//tissue homeostasis;GO:0023033;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0034331;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0012501//programmed cell death;GO:0023060;GO:0001894//tissue homeostasis;GO:0023033;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0034331;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process 32986 6761.09 26.725 32.485 0.281583757238562 Up 0.453407740060758 CG12531 CG12531, isoform B K13871|1|0.0|1420|dme:Dmel_CG12531|solute carrier family 7 (cationic amino acid transporter), member 14 GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity GO:0015837//amine transport 33267 1073.00 0.73 1.155 0.66192448253604 Up 0.206511689340906 CG13950 CG13950 - - GO:0030246//carbohydrate binding - 41830 2086.00 5.065 4.69 -0.110974346285762 Down 0.132049927354379 CG4203 CG4203 K11266|1|0.0|1185|dme:Dmel_CG4203|MAternally affected uncoordination - - - 40479 1373.42 1.805 1.495 -0.271853352689066 Down 0.146975300488707 CG14457 CG14457, isoform C - - - - 40428 1800.00 0.9 0.39 -1.20645087746743 Down 0.255745608241976 eg eagle, isoform C K08706|1|0.0|677|dme:Dmel_CG7383|nuclear receptor subfamily 0 group A GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 41592 3953.12 16.18 18.585 0.19992708043178 Up 0.331693303394532 CG31342 CG31342, isoform C - - - - 33056 2739.24 6.06 6.23 0.0399143695510509 Up 0.0758816536785101 Cyp6v1 Cyp6v1, isoform C K00517|1|0.0|1013|dme:Dmel_CG1829| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 39421 3174.00 2.855 1.78 -0.681613504396445 Down 0.330735702020869 CG10663 CG10663, isoform D K01324|1|1e-44|182|bta:533547|plasma kallikrein [EC:3.4.21.34];K01316|2|3e-44|180|oaa:100079480|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K09633|3|2e-43|177|mcc:715138|transmembrane protease, serine 2 [EC:3.4.21.-];K01320|4|3e-43|177|dre:114423|coagulation factor VII [EC:3.4.21.21];K09614|5|5e-43|176|bta:527107|corin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 12798334 390.00 7.02 9.465 0.431131475399145 Up 0.427816668868049 CG43202 CG43202 - - - - 318032 380.80 35.1 37.04 0.0776130680683133 Up 0.194789327697794 CG32448 CG32448, isoform C - - - - 34799 906.40 2.71 1.97 -0.460097221897495 Down 0.259939241843878 CG8997 CG8997, isoform B - - - - 19835190 367.00 0.01 0.165 4.04439411935845 Up 0.184883106590939 31594 2217.00 0.475 1.14 1.26303440583379 Up 0.294115704662528 Apc7 anaphase promoting complex subunit 7, isoform B K03354|1|0.0|1093|dme:Dmel_CG14444|anaphase-promoting complex subunit 7 - - - 34124 928.00 0.925 1.775 0.940293753875732 Up 0.316206577730815 CG8349 CG8349 K01489|1|4e-135|480|dme:Dmel_CG8349|cytidine deaminase [EC:3.5.4.5] - GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding GO:0046131 39172 1534.00 13.325 14.945 0.165527364031556 Up 0.276218465196143 CG6685 CG6685, isoform B - - - - 31800 6666.73 18.52 18.34 -0.014090459665182 Down 0.0600977413815876 Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein, isoform D - GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome GO:0030695//GTPase regulator activity;GO:0030695//GTPase regulator activity;GO:0030695//GTPase regulator activity GO:0008104//protein localization;GO:0071711//basement membrane organization;GO:0008104//protein localization;GO:0071711//basement membrane organization;GO:0008104//protein localization;GO:0071711//basement membrane organization 40832 2739.00 15.235 12.43 -0.293563203634001 Down 0.399187689869238 Dfd deformed K09304|1|0.0|744|dme:Dmel_CG2189|homeobox protein HoxA/B/C/D4 - GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0012502//induction of programmed cell death;GO:0009653//anatomical structure morphogenesis;GO:0007275//multicellular organismal development 32009 10157.07 4.905 5.31 0.114458724584915 Up 0.137069079381852 Imp IGF-II mRNA-binding protein, isoform M K13197|1|7e-85|316|xla:379623|insulin-like growth factor 2 mRNA-binding protein 3 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation;GO:0007416//synapse assembly;GO:0000377;GO:0048232//male gamete generation 43188 1452.00 0.25 0.275 0.137503523749935 Up 0.049861312904504 CG14239 pickpocket 15 K04832|1|3e-16|86.7|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|2|5e-07|55.8|dre:407672|amiloride-sensitive cation channel 2, neuronal GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 10178954 527.00 0.465 0.18 -1.36923380966572 Down 0.19323735305772 CG42798 CG42798, isoform B - - - - 318098 1402.98 0.175 11.905 6.08806888832537 Up 0.861279883767006 CG32581 CG32581, isoform B K10666|1|7e-124|444|dme:Dmel_CG8974|E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 37445 2327.09 22.29 18.065 -0.303199361827309 Down 0.444756306960771 Acox57D-p acyl-Coenzyme A oxidase at 57D proximal, isoform B K00232|1|0.0|1338|dme:Dmel_CG9707|acyl-CoA oxidase [EC:1.3.3.6] - - - 39071 987.00 40.43 74.995 0.891368209123387 Up 0.704200237749307 Hsp67Bc heat shock gene 67Bc K09542|1|2e-20|99.4|dme:Dmel_CG4533|crystallin, alpha B;K09541|2|1e-16|87.4|dre:100000769|crystallin, alpha A - - GO:0006950//response to stress 43744 1996.00 0.395 0.525 0.41046476948902 Up 0.10553427552503 Smvt Sodium-dependent multivitamin transporter K03307|1|7e-94|345|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport 5740248 396.00 0.01 0.15 3.90689059560852 Up 0.171410645885616 robls54B roadblock similar 54B, isoform B K10419|1|3e-12|69.7|phu:Phum_PHUM551150|dynein light chain roadblock-type GO:0005875//microtubule associated complex GO:0016887//ATPase activity - 318243 1182.00 1.735 0.96 -0.853829351857105 Down 0.295997886672831 CG32845 CG32845 K09578|1|7e-28|124|api:100166101|peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8] - GO:0045309//protein phosphorylated amino acid binding;GO:0016859//cis-trans isomerase activity;GO:0016597//amino acid binding GO:0001932//regulation of protein phosphorylation;GO:0031398//positive regulation of protein ubiquitination;GO:0007179//transforming growth factor beta receptor signaling pathway 35258 2062.00 8.53 9.34 0.130876808391372 Up 0.19462422401268 CG10366 CG10366 K09228|1|9e-41|168|ptr:455885|KRAB domain-containing zinc finger protein GO:0044421//extracellular region part;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 43722 1741.50 32.705 31.015 -0.0765450895223062 Down 0.190562673358869 CG1774 CG1774, isoform B K12417|1|3e-10|67.4|tgu:100227949|acyl-CoA thioesteraes 11 [EC:3.1.2.-] - - GO:0008152//metabolic process 35822 1783.00 63.5 60.665 -0.0658921823182108 Down 0.188317263241316 Cyp4e2 cytochrome P450-4e2, isoform B K00517|1|0.0|999|dme:Dmel_CG2060| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 38708 505.00 27.335 13.015 -1.07057406379547 Down 0.688086118082156 Lcp65Ac Lcp65Ac - - GO:0042302//structural constituent of cuticle GO:0051234//establishment of localization 64879 1814.00 2.105 3.165 0.588385266361945 Up 0.321787082287677 Msi Male-specific insect derived growth factor, isoform C K01488|1|2e-88|326|dpo:Dpse_GA19282|adenosine deaminase [EC:3.5.4.4] GO:0005626//insoluble fraction;GO:0031224//intrinsic to membrane;GO:0044421//extracellular region part;GO:0005626//insoluble fraction;GO:0031224//intrinsic to membrane;GO:0044421//extracellular region part;GO:0005626//insoluble fraction;GO:0031224//intrinsic to membrane;GO:0044421//extracellular region part GO:0030371//translation repressor activity;GO:0003723//RNA binding;GO:0005102//receptor binding;GO:0003824//catalytic activity;GO:0030371//translation repressor activity;GO:0003723//RNA binding;GO:0005102//receptor binding;GO:0003824//catalytic activity;GO:0030371//translation repressor activity;GO:0003723//RNA binding;GO:0005102//receptor binding;GO:0003824//catalytic activity GO:0006412//translation;GO:0006396//RNA processing;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0045165//cell fate commitment;GO:0007281//germ cell development;GO:0006412//translation;GO:0006396//RNA processing;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0045165//cell fate commitment;GO:0007281//germ cell development;GO:0006412//translation;GO:0006396//RNA processing;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0045165//cell fate commitment;GO:0007281//germ cell development 44207 819.00 235.28 252.62 0.102590172901872 Up 0.262580900805706 ND23 NADH:ubiquinone reductase 23kD subunit precursor K03941|1|3e-125|447|dme:Dmel_CG3944|NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain 37355 3887.00 1.99 1.575 -0.33741660215637 Down 0.181845198784837 insc inscuteable - - - - 35671 1986.00 199.7 212.895 0.0923077346226437 Up 0.241348566900013 Inos inos K01858|1|0.0|1129|dme:Dmel_CG11143|myo-inositol-1-phosphate synthase [EC:5.5.1.4] GO:0044424//intracellular part GO:0016872//intramolecular lyase activity GO:0006644//phospholipid metabolic process;GO:0006020//inositol metabolic process 3772083 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33876 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 5740547 1873.00 6.005 2.675 -1.16662535441713 Down 0.556168273675868 CG34461 CG34461, isoform B - - GO:0042302//structural constituent of cuticle - 35090 6634.02 11.245 14.315 0.348244009221536 Up 0.435840707964602 CG42750 CG42750, isoform C K01273|1|0.0|1182|dme:Dmel_CG42400|membrane dipeptidase [EC:3.4.13.19];K06776|2|1e-172|608|dpo:Dpse_GA20160|protein tyrosine phosphatase, receptor type, K [EC:3.1.3.48] - GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process 36621 8483.51 6.405 6.42 0.00337472678065657 Up 0.0401862369568089 Su(var)2-HP2 Su(var)2-HP2, isoform B K04574|1|2e-06|56.2|ssc:100156492|neurofilament heavy polypeptide GO:0000785//chromatin;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000070//mitotic sister chromatid segregation;GO:0006338//chromatin remodeling;GO:0000070//mitotic sister chromatid segregation;GO:0006338//chromatin remodeling 38081 1457.40 11.945 10.765 -0.150058534289098 Down 0.236758684453837 CG3386 CG3386, isoform D - - - - 38408 333.00 0.415 1.005 1.276012259832 Up 0.278827103420948 Drsl2 Drosomycin-like 2 - - - GO:0050832//defense response to fungus;GO:0042742//defense response to bacterium 33024 2785.00 5.635 5.475 -0.0415566456836854 Down 0.0744617619865275 CG17068 CG17068 K10478|1|2e-32|141|phu:Phum_PHUM452460|BTB/POZ domain-containing protein 3/6;K10477|3|2e-31|138|spu:578095|BTB/POZ domain-containing protein 1/2 - GO:0005488//binding - 33201 1325.50 15.785 13.975 -0.175705977582433 Down 0.293026020340774 U2af38 U2 small nuclear riboprotein auxiliary factor 38, isoform B K12836|1|2e-105|382|dvi:Dvir_GJ17240|splicing factor U2AF 35 kDa subunit GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0003727//single-stranded RNA binding;GO:0046914//transition metal ion binding GO:0000278//mitotic cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome 32612 1697.31 35.375 31.28 -0.177489635299255 Down 0.349425439175802 Anxb11 annexin B11, isoform G - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0003676//nucleic acid binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0003676//nucleic acid binding;GO:0008092//cytoskeletal protein binding GO:0065008;GO:0006355//regulation of transcription, DNA-dependent;GO:0065008;GO:0006355//regulation of transcription, DNA-dependent 3772560 1278.90 45.695 47.76 0.0637665240511774 Up 0.167382115968828 CG33714 CG33714, isoform B K06270|1|5e-12|72.4|dre:445393|protein phosphatase 1 regulatory subunit 12A - GO:0005504//fatty acid binding;GO:0005504//fatty acid binding - 14462712 375.00 0.58 1.665 1.52139737194369 Up 0.38195086514331 CG43922 CG43922 - - - - 36915 7848.79 22.935 22.445 -0.0311568111664159 Down 0.0964535728437459 RhoGEF2 Rho guanine nucleotide exchange factor 2, isoform H K12331|1|1e-55|219|ssc:100157291|Rho guanine nucleotide exchange factor 11 - - - 42179 1606.00 20.905 20.84 -0.00449276576562933 Down 0.0447430986659622 CG14314 CG14314 - - - - 37364 2976.68 3.19 4.71 0.562170635847914 Up 0.376370360586448 otp orthopedia, isoform K K09452|1|3e-15|84.7|dpo:Dpse_GA17785|homeobox protein aristaless-related - - - 45233 2352.26 47.33 52.355 0.145572401722469 Up 0.324065513142253 capt capulet, isoform C - GO:0044424//intracellular part;GO:0044424//intracellular part GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0065008;GO:0001654//eye development;GO:0007015//actin filament organization;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032989;GO:0007292//female gamete generation;GO:0009887//organ morphogenesis;GO:0007017//microtubule-based process;GO:0065008;GO:0001654//eye development;GO:0007015//actin filament organization;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032989;GO:0007292//female gamete generation;GO:0009887//organ morphogenesis;GO:0007017//microtubule-based process 38287 1149.00 12.59 13.25 0.0737140766189073 Up 0.141956148461234 CG2034 CG2034, isoform B - - - - 41247 5803.00 85.63 106.05 0.308556390289024 Up 0.527407211728966 Syn synapsin, isoform F - GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle GO:0032559;GO:0032559;GO:0032559;GO:0032559 GO:0001505//regulation of neurotransmitter levels;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006887//exocytosis 317924 1606.00 11.215 13.42 0.258955051113911 Up 0.35599656584335 CG32221 CG32221 - - - - 35625 889.00 0.725 0.99 0.449447530064675 Up 0.149286752080306 Tsp42Eo tetraspanin 42Eo K06497|1|5e-06|51.6|aga:AgaP_AGAP007209|CD63 antigen GO:0031224//intrinsic to membrane - - 36040 3024.41 131.91 96.43 -0.451999985176943 Down 0.615770704002113 TER94 TER94, isoform E K13525|1|0.0|1459|dsi:Dsim_GD10706|transitional endoplasmic reticulum ATPase GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0004175//endopeptidase activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0004175//endopeptidase activity;GO:0032559;GO:0042623//ATPase activity, coupled GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0048284//organelle fusion;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0042051//compound eye photoreceptor development;GO:0019538//protein metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0048284//organelle fusion;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0042051//compound eye photoreceptor development;GO:0019538//protein metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0048284//organelle fusion;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0042051//compound eye photoreceptor development;GO:0019538//protein metabolic process 39876 2010.00 11.295 9.27 -0.285043026767554 Down 0.361411966715097 CG9706 CG9706, isoform B K03372|1|0.0|808|dpo:Dpse_GA21979|MFS transporter, PAT family, solute carrier family 33 (acetyl-CoA transportor), member 1 [EC:2.3.1.-] - - GO:0006810//transport;GO:0006810//transport 2768860 979.00 0.24 0.365 0.604862058158861 Up 0.106161669528464 CG33225 CG33225, isoform C K01312|1|1e-27|124|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01310|2|2e-27|122|oaa:100082597|chymotrypsin [EC:3.4.21.1];K01335|3|4e-27|122|spu:373308|component factor B [EC:3.4.21.47];K01321|4|4e-27|122|xla:100049721|coagulation factor IX (Christmas factor) [EC:3.4.21.22] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835576 419.00 8.495 4.34 -0.968918904739741 Down 0.571192709021265 40526 1462.00 4.875 2.36 -1.04661535927513 Down 0.504721965394268 CG14636 CG14636, isoform B - - - - 40505 644.00 81 87.245 0.107150545022424 Up 0.26911900673623 CG11137 CG11137 - - - - 246452 675.00 13.485 16.135 0.258838056251339 Up 0.376139215427288 CG30094 CG30094 - - GO:0046914//transition metal ion binding - 36251 1038.00 15.645 18.115 0.211483147212366 Up 0.340146612072381 Buffy buffy K02561|1|8e-22|104|xla:100271896|BCL2-related ovarian killer protein - - GO:0012502//induction of programmed cell death;GO:0043066//negative regulation of apoptotic process 32211 1494.91 14.37 18.81 0.388439787065859 Up 0.488376700567957 CG1463 CG1463, isoform C - - - - 44856 1798.00 4.02 5.96 0.568116829283233 Up 0.41682076343944 ru roughoid K02857|1|1e-65|251|dse:Dsec_GM14413|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral to membrane GO:0004175//endopeptidase activity GO:0035272//exocrine system development;GO:0051605;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0007424//open tracheal system development;GO:0001742//oenocyte differentiation;GO:0030534//adult behavior;GO:0001708//cell fate specification;GO:0051301//cell division;GO:0008306//associative learning;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0010669//epithelial structure maintenance;GO:0042675//compound eye cone cell differentiation;GO:0007165//signal transduction;GO:0007445;GO:0035466;GO:0007476//imaginal disc-derived wing morphogenesis 19834792 539.00 0.38 0.375 -0.0191088229477047 Down 0.0413749834896315 31408 2788.72 10.84 13.14 0.277600518968458 Up 0.372044644036455 Proc-R proctolin receptor, isoform E K04282|1|2e-12|75.9|mmu:22045|thyrotropin-releasing hormone receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 32708 1497.00 0.05 1.44 4.84799690655495 Up 0.524006075815612 CG18258 CG18258 K01059|1|2e-67|256|dpo:Dpse_GA19044|lipoprotein lipase [EC:3.1.1.34];K01046|3|3e-23|109|ssc:100155399|triacylglycerol lipase [EC:3.1.1.3] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 32435 1176.51 10.595 10.85 0.0343114549596722 Up 0.0823537181349888 opm opossum, isoform C K05409|1|1e-13|76.6|mdo:100029323|TRIF-related adaptor molecule;K01529|3|6e-10|64.7|mcc:709884| [EC:3.6.1.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0051234//establishment of localization;GO:0051234//establishment of localization 41741 740.12 24.645 20.985 -0.231936517785321 Down 0.385517104741778 RpII15 RNA polymerase II 15kD subunit, isoform C K03017|1|9e-76|282|dya:Dyak_GE24228|DNA-directed RNA polymerase II subunit I - - - 35848 1431.00 5.055 5.345 0.080478855817476 Up 0.106260731739532 beta3GalTII galactosyltransferase II K00734|1|3e-44|179|ame:552538|galactosylxylosylprotein 3-beta-galactosyltransferase [EC:2.4.1.134] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0030166//proteoglycan biosynthetic process;GO:0006024//glycosaminoglycan biosynthetic process 3771738 1590.40 90.47 61.475 -0.557439641640406 Down 0.647107383436798 CG9510 CG9510, isoform D K01755|1|0.0|930|dme:Dmel_CG9510|argininosuccinate lyase [EC:4.3.2.1] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016842;GO:0016842 GO:0006526//arginine biosynthetic process;GO:0006526//arginine biosynthetic process 318996 1047.43 0.385 0.84 1.12553088208386 Up 0.240159820367191 CG31875 CG31875, isoform D - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 35200 3187.00 11.045 14.085 0.350766145019656 Up 0.434651961431779 pigeon pigeon, isoform B - - - GO:0007612//learning;GO:0007612//learning 19835628 331.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 318066 7087.52 60.21 36.075 -0.739003722705213 Down 0.677123233390569 CG34120 CG34120, isoform E K05643|1|2e-90|335|gga:416386|ATP-binding cassette, subfamily A (ABC1), member 3 GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 35993 1750.92 43.42 48.375 0.15590193530399 Up 0.335754854048342 CG1902 CG1902, isoform C - - - - 37853 493.70 662.995 381.995 -0.795444235549242 Down 0.714337604015322 Mlp60A muscle LIM protein at 60A, isoform F K09377|1|6e-40|166|mdo:100016597|cysteine and glycine-rich protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0048869//cellular developmental process;GO:0014706//striated muscle tissue development 33832 1196.00 0.485 0.965 0.992544195080953 Up 0.238772949412231 Ucp4C Ucp4C K03454|1|2e-43|176|bfo:BRAFLDRAFT_277098|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006818//hydrogen transport 43284 1587.50 40.32 38.745 -0.05748549466076 Down 0.161966715097081 TfIIA-L transcription factor IIA L, isoform C K03122|1|4e-124|444|dme:Dmel_CG5930|transcription initiation factor TFIIA large subunit GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003702//RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 5740515 622.93 1.67 1.42 -0.23395717296937 Down 0.125643904371946 CG34178 CG34178, isoform C - - - - 14462580 737.00 0.14 0.2 0.514573172829758 Up 0.0790516444327037 38405 3235.00 0.06 0.03 -1 Down 0.0654471007792894 CG12009 CG12009, isoform B - - - - 2768901 607.00 0.11 0.38 1.78849589480629 Up 0.192676000528332 Ste:CG33239 Ste:CG33239 K08282|1|1e-95|348|dme:Dmel_CG33241|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 40359 2980.01 29.375 33.405 0.185475207169221 Up 0.358869369964338 Rab26 Rab26, isoform G K07914|1|2e-72|273|cfa:483298|Ras-related protein Rab-37;K07913|2|1e-71|271|gga:416554|Ras-related protein Rab-26 GO:0031224//intrinsic to membrane;GO:0031410//cytoplasmic vesicle;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0006887//exocytosis;GO:0035556//intracellular signal transduction;GO:0006887//exocytosis;GO:0035556//intracellular signal transduction;GO:0006887//exocytosis 19836150 334.00 0.135 0.15 0.15200309344505 Up 0.045238409721305 326141 581.00 26.525 27.265 0.0396974043171463 Up 0.116992471271959 mRpS18A mitochondrial ribosomal protein S18A - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 40787 2280.23 28.925 21.36 -0.437405312307298 Down 0.552337868181218 CG1041 CG1041, isoform D K00624|1|0.0|1285|dme:Dmel_CG1041|carnitine O-acetyltransferase [EC:2.3.1.7] GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0019866//organelle inner membrane;GO:0042579//microbody GO:0016406;GO:0016406 GO:0032787//monocarboxylic acid metabolic process;GO:0006577;GO:0032787//monocarboxylic acid metabolic process;GO:0006577 12798283 535.00 0.875 1.16 0.406769883295243 Up 0.15315017831198 53503 1773.00 0.26 0.17 -0.612976876890753 Down 0.094208162726192 Ugt86Dh Ugt86Dh, isoform B K00699|1|0.0|1037|dme:Dmel_CG4772|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 31166 3619.99 140.435 102.535 -0.453786083804225 Down 0.616761326112799 Actn alpha actinin, isoform J K05699|1|0.0|1777|dvi:Dvir_GJ16390|actinin alpha GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0031674//I band GO:0046872//metal ion binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0003779//actin binding GO:0007015//actin filament organization;GO:0007015//actin filament organization 43191 1569.00 1.595 2.84 0.832334505739813 Up 0.368907674019284 Hex-t2 Hex-t2 K00844|1|0.0|958|dme:Dmel_CG32849|hexokinase [EC:2.7.1.1] - GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559 GO:0006007//glucose catabolic process 32624 4373.21 24.74 27.85 0.170831827251024 Up 0.325980715889579 Pp2B-14D protein phosphatase 2B at 14D, isoform C K04348|1|0.0|1040|dse:Dsec_GM13390|protein phosphatase 3, catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding GO:0007126//meiosis;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0007444//imaginal disc development;GO:0006464//cellular protein modification process 40370 3736.95 20.485 20.885 0.0278992506824916 Up 0.0926231673490952 Aef1 adult enhancer factor 1, isoform D K09228|1|7e-35|149|bta:525942|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter 41039 1141.00 0.1 0.21 1.0703893278914 Up 0.11236956808876 CG11762 CG11762 K09228|1|2e-34|145|rno:684006|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 33241 700.57 8.03 6.64 -0.27421674617039 Down 0.305705983357549 CG13689 CG13689, isoform B - - - - 31139 3411.60 1.235 1.845 0.579109774475719 Up 0.244914806498481 CG14814 CG14814, isoform D - - - - 32935 5318.68 8.395 9.365 0.157748669306015 Up 0.223748514066834 pcm pacman, isoform B K12618|1|0.0|2938|dme:Dmel_CG3291|5'-3' exoribonuclease 1 [EC:3.1.13.-] GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0008409//5'-3' exonuclease activity;GO:0005488//binding;GO:0008409//5'-3' exonuclease activity;GO:0005488//binding GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0009611//response to wounding;GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048232//male gamete generation;GO:0035194//posttranscriptional gene silencing by RNA;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0009611//response to wounding;GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048232//male gamete generation;GO:0035194//posttranscriptional gene silencing by RNA 43683 2072.69 51.655 148.37 1.52221950439001 Up 0.76482631092326 stops slow termination of phototransduction, isoform C K10339|1|0.0|930|dsi:Dsim_GD16578|ankyrin repeat and SOCS box protein 17 - - GO:0009586;GO:0009586;GO:0009586 39816 1447.00 31.67 145.035 2.19521232247367 Up 0.792761854444591 Cpr72Ec cuticular protein 72Ec - - GO:0005198//structural molecule activity;GO:0005488//binding - 3772702 1023.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 His1:CG33846 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 2768910 2632.00 0.205 0.46 1.16600995143893 Up 0.172995641262713 CG33310 CG33310 K01540|1|4e-13|77.4|tca:662497|sodium/potassium-transporting ATPase subunit beta GO:0044464//cell part - GO:0009206;GO:0030001//metal ion transport 318886 6113.49 5.16 6.61 0.357279206084437 Up 0.33862765816933 CG31687 CG31687, isoform C K03355|1|0.0|709|dme:Dmel_CG31687|anaphase-promoting complex subunit 8 GO:0000152//nuclear ubiquitin ligase complex - GO:0006909//phagocytosis;GO:0007088//regulation of mitosis 35228 1560.16 5.97 5.03 -0.247172531459278 Down 0.25023114515916 CG10195 CG10195, isoform C K13355|1|3e-114|412|dmo:Dmoj_GI19813|nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-] - GO:0003824//catalytic activity - 3772013 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33906 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 44510 1535.43 51.29 38.935 -0.39760994504744 Down 0.562739400343416 cv crossveinless, isoform C K01810|1|2e-32|140|bmy:Bm1_47625|glucose-6-phosphate isomerase [EC:5.3.1.9] - - GO:0008344//adult locomotory behavior 32593 2739.83 12.035 11.805 -0.0278381002458544 Down 0.0789195614846123 CG9915 CG9915, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0008135//translation factor activity, nucleic acid binding;GO:0030528//transcription regulator activity GO:0006351//transcription, DNA-dependent 36333 2830.00 128.195 160.85 0.327375942488573 Up 0.551908598599921 CG17739 CG17739 K04659|1|3e-09|64.3|dre:794881|thrombospondin - GO:0004866//endopeptidase inhibitor activity - 37224 3100.43 1.235 2.53 1.03462634310963 Up 0.392814687623828 CG10062 CG10062, isoform D - - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 40377 710.00 16.925 15.97 -0.0837915210511267 Down 0.168042530709285 CG7519 CG7519, isoform B - - - - 33011 609.00 54.165 49.585 -0.127457165284974 Down 0.294743098665962 CG34331 CG34331, isoform C - - - - 10178918 390.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG42689 CG42689 - - - - 40169 6270.60 21.71 27.5 0.34107189268424 Up 0.492108043851539 CG8334 CG8334, isoform E - - - - 32170 1523.00 22.395 26.535 0.244719882555917 Up 0.400706643772289 Cyp311a1 Cyp311a1 K00517|1|6e-60|232|dme:Dmel_CG3466| [EC:1.14.-.-];K07427|2|6e-60|232|xtr:780124|cytochrome P450, family 4, subfamily V GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 36720 1698.00 21.245 22.25 0.0666819924278363 Up 0.160282657508916 CG8187 CG8187 - - - GO:0002526//acute inflammatory response 32575 2006.00 0.515 0.825 0.679821687062597 Up 0.174679698850878 CG8958 CG8958 - - - - 42890 2292.03 1.225 3.235 1.40098396298994 Up 0.485768062343152 Orct2 organic cation transporter 2, isoform B K08202|1|0.0|793|dme:Dmel_CG6331|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane GO:0008324//cation transmembrane transporter activity GO:0001700//embryonic development via the syncytial blastoderm;GO:0035264//multicellular organism growth;GO:0016049//cell growth;GO:0006812//cation transport;GO:0012501//programmed cell death 37317 473.41 74.92 42.855 -0.805887362585517 Down 0.692907145687492 CG13428 CG13428, isoform B - - - - 3355069 1186.02 113.725 109.035 -0.0607581232853578 Down 0.176561880861181 CG17691 CG17691, isoform F K00167|1|0.0|757|dme:Dmel_CG17691|2-oxoisovalerate dehydrogenase E1 component, beta subunit [EC:1.2.4.4] - GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0035337;GO:0035337;GO:0035337 14462665 1006.00 0.045 0.135 1.58496250072116 Up 0.107218333113195 35103 2079.22 16.04 12.55 -0.353986777616786 Down 0.449709417514199 CG10176 CG10176, isoform C - - - - 39297 3268.00 6.92 4.96 -0.48043191724985 Down 0.404636111478008 rt rotated abdomen K00728|1|0.0|1664|dme:Dmel_CG6097|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0000030//mannosyltransferase activity GO:0006486//protein glycosylation;GO:0048513//organ development;GO:0035292//specification of segmental identity, trunk;GO:0030258//lipid modification 59128 1113.61 7.455 6.975 -0.0960151355668926 Down 0.142583542464668 CG15107 CG15107, isoform B - GO:0000785//chromatin - GO:0050789//regulation of biological process 12798125 483.00 0.09 0.1 0.15200309344505 Up 0.045238409721305 CG43308 CG43308, isoform B - - - - 42547 2670.00 2.02 2.665 0.399780240007381 Up 0.234876502443535 slou slouch, isoform B K09309|1|4e-156|552|dme:Dmel_CG6534|homeobox protein Nkx-1 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048856//anatomical structure development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007275//multicellular organismal development 12798164 498.00 0.17 0.315 0.889817082249577 Up 0.121648395192181 14462573 1200.00 1.455 1.84 0.338686613148729 Up 0.174910844010038 318982 860.00 0.275 0.255 -0.108934371553164 Down 0.0478470479461102 CG31851 CG31851, isoform B K00670|1|4e-99|360|dme:Dmel_CG31851|peptide alpha-N-acetyltransferase [EC:2.3.1.88] GO:0044464//cell part GO:0016407//acetyltransferase activity - 40197 1397.00 0.31 0.29 -0.0962153152593032 Down 0.0473847576277902 CG14185 CG14185 K11092|1|2e-07|57.0|aag:AaeL_AAEL006840|U2 small nuclear ribonucleoprotein A';K05956|4|2e-06|53.9|oaa:100087390|geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] - - - 41412 1277.34 0.57 1.085 0.928661218279738 Up 0.247523444723286 CG14717 CG14717, isoform B K13703|1|6e-32|138|aag:AaeL_AAEL007243|abhydrolase domain-containing protein 11 - - - 7354425 1950.00 25.825 23.88 -0.112965512487617 Down 0.235074626865672 CG42306 CG42306, isoform C K14011|1|0.0|751|dme:Dmel_CG5469|UBX domain-containing protein 6 - - - 33470 1460.73 68.745 78.575 0.192815580590644 Up 0.394201558578787 colt congested-like trachea, isoform D K03454|1|5e-109|394|dpo:Dpse_GA17470|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0015300;GO:0015300 GO:0006909//phagocytosis;GO:0046907//intracellular transport;GO:0051181//cofactor transport;GO:0006865//amino acid transport;GO:0006909//phagocytosis;GO:0046907//intracellular transport;GO:0051181//cofactor transport;GO:0006865//amino acid transport 38880 1301.00 9.065 10.245 0.176541059267089 Up 0.252641658961828 CG8281 CG8281 - - - - 59151 495.00 27.595 26.71 -0.0470269095565858 Down 0.132908466516973 mRpL36 mitochondrial ribosomal protein L36 - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 53557 4053.08 5.25 6.915 0.397411828597009 Up 0.365176330735702 esn espinas, isoform D K04511|1|0.0|1389|dme:Dmel_CG12833|prickle GO:0016020//membrane;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0009798//axis specification;GO:0001738//morphogenesis of a polarized epithelium;GO:0009798//axis specification;GO:0001738//morphogenesis of a polarized epithelium 31239 3415.07 32.99 37.04 0.167055320695305 Up 0.338924844802536 egh egghead, isoform D K02359|1|0.0|884|dme:Dmel_CG9659|egghead protein (zeste-white 4 protein) - - - 37283 753.00 31.13 29.655 -0.0700302050188154 Down 0.172896579051644 CG13869 CG13869 - - - - 34684 3478.00 12.6 12.715 0.0131077283028274 Up 0.0563994188350284 CG5787 CG5787, isoform B K12898|1|1e-08|62.8|dya:Dyak_GE10080|heterogeneous nuclear ribonucleoprotein F/H;K13092|3|6e-06|53.9|nvi:100122789|nuclear protein NHN1 - - - 36462 1768.00 34.415 34.725 0.0129371842540506 Up 0.0641923127724211 Pex13 peroxin 13 K13344|1|3e-167|588|dme:Dmel_CG4663|peroxin-13 GO:0031224//intrinsic to membrane;GO:0042579//microbody - GO:0016558//protein import into peroxisome matrix 246599 1072.23 55.975 36.18 -0.629590215118719 Down 0.649022586184124 Rpi Ribose-5-phosphate isomerase, isoform C K01807|1|2e-158|558|dse:Dsec_GM16000|ribose 5-phosphate isomerase A [EC:5.3.1.6] - GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0006098//pentose-phosphate shunt 318225 1803.22 19.605 9.285 -1.07824782658117 Down 0.669660546823405 CG32816 CG32816, isoform F - - - - 44672 5700.05 162.44 175.45 0.111153015365203 Up 0.27965262184652 Lk6 Lk6, isoform B K04372|1|1e-153|545|tca:658754|MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0012505//endomembrane system;GO:0005815//microtubule organizing center;GO:0012505//endomembrane system GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006412//translation;GO:0050896//response to stimulus;GO:0040007//growth;GO:0006464//cellular protein modification process;GO:0006412//translation;GO:0050896//response to stimulus;GO:0040007//growth;GO:0006464//cellular protein modification process 19835064 829.00 0.73 0.585 -0.319459839296613 Down 0.108440100383041 42733 4160.73 187.335 209.295 0.159917381384393 Up 0.366001849161273 CG13830 CG13830, isoform E K08136|1|1e-44|181|isc:IscW_ISCW022173|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0046872//metal ion binding;GO:0046872//metal ion binding - 41539 733.00 1.19 1.255 0.0767257906428285 Up 0.0592061814819707 CG5509 CG5509 - - - - 12798292 568.00 0.29 0.01 -4.85798099512757 Down 0.265024435345397 CG43181 CG43181 - - - - 326196 3038.00 1.235 0.01 -6.94836723158468 Down 0.549564126271298 CG32088 CG32088 K05315|1|3e-90|333|dwi:Dwil_GK18110|voltage-dependent calcium channel alpha 1, invertebrate - GO:0005216//ion channel activity GO:0006810//transport 40315 883.00 1.235 1.385 0.165374934464511 Up 0.0943402456742835 Sems seminase K01312|1|6e-28|124|dme:Dmel_CG12386|trypsin [EC:3.4.21.4];K09635|4|9e-27|120|mdo:100031528|transmembrane protease, serine 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 45784 2350.26 42.06 46.73 0.15190018713302 Up 0.321291771232334 Aats-thr Threonyl-tRNA synthetase, isoform D K01868|1|0.0|1335|dme:Dmel_CG5353|threonyl-tRNA synthetase [EC:6.1.1.3] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0007033//vacuole organization;GO:0006418//tRNA aminoacylation for protein translation;GO:0007033//vacuole organization;GO:0006418//tRNA aminoacylation for protein translation;GO:0007033//vacuole organization 35139 1807.00 16.615 3.5 -2.2470594658597 Down 0.735900145291243 CG17322 CG17322, isoform D K00699|1|3e-172|605|dme:Dmel_CG17323|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior 45959 2115.78 179.195 176.415 -0.0225571492364917 Down 0.0919957733456611 mts microtubule star, isoform C K04382|1|0.0|653|dya:Dyak_GE14639|protein phosphatase 2 (formerly 2A), catalytic subunit [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle;GO:0044430//cytoskeletal part;GO:0044427//chromosomal part;GO:0008287//protein serine/threonine phosphatase complex GO:0004721//phosphoprotein phosphatase activity;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0030234//enzyme regulator activity GO:0006909//phagocytosis;GO:0010467//gene expression;GO:0016055//Wnt receptor signaling pathway;GO:0046578//regulation of Ras protein signal transduction;GO:0007051//spindle organization;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0007405//neuroblast proliferation;GO:0000302//response to reactive oxygen species;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030036//actin cytoskeleton organization;GO:0006915//apoptotic process;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0030010//establishment of cell polarity;GO:0009314//response to radiation;GO:0008589//regulation of smoothened signaling pathway;GO:0000087//M phase of mitotic cell cycle 41585 968.00 0.165 0.395 1.25938662881865 Up 0.167018887861577 Spc25 Spc25 - - - - 246393 446.00 1.22 0.77 -0.663950796867985 Down 0.211695945053494 CG30016 CG30016 K07127|1|2e-61|233|dme:Dmel_CG30016|5-hydroxyisourate hydrolase [EC:3.5.2.17] - - GO:0051234//establishment of localization 38562 3799.90 98.405 106.49 0.113914433278234 Up 0.273477744023247 CG42540 CG42540, isoform K K03364|1|1e-15|85.9|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 37607 689.00 0.355 0.135 -1.39485961734121 Down 0.1658961828028 Obp58b Odorant-binding protein 58b - - GO:0005488//binding GO:0051234//establishment of localization 19834823 818.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 - CG45544, isoform B - - - - 326135 1681.00 33.83 29.16 -0.214312457467051 Down 0.384394399683001 CG31357 CG31357 - - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 19835222 1098.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 37247 2804.00 16.675 14.99 -0.153686378124088 Down 0.265882974507991 hpo hippo, isoform B K04412|1|8e-145|514|ame:410208|serine/threonine kinase 3 [EC:2.7.11.5];K04411|3|2e-130|467|spu:576378|serine/threonine kinase 4 [EC:2.7.11.6] - - - 318741 869.00 0.365 0.055 -2.73039294024272 Down 0.223253203011491 CG31446 CG31446, isoform B - - - - 36227 2065.37 13.665 15.745 0.204408297612203 Up 0.318187821952186 CG13204 CG13204, isoform B - GO:0044464//cell part;GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 19835007 594.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 3772077 1023.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 His1:CG33837 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 32427 815.00 0.195 0.27 0.46948528330122 Up 0.088264430062079 CG9030 CG9030 - - - GO:0006519 34750 1972.00 6.475 5.655 -0.195353168584096 Down 0.222823933430194 CG9302 CG9302 K09583|1|0.0|962|dme:Dmel_CG9302|protein disulfide isomerase family A, member 5 [EC:5.3.4.1] - GO:0003824//catalytic activity GO:0019725//cellular homeostasis 35851 5521.00 1.505 1.49 -0.0144511562975404 Down 0.041044776119403 ptc patched K06225|1|0.0|2326|dme:Dmel_CG2411|patched 1 GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral to membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0000278//mitotic cell cycle;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0035161;GO:0048878//chemical homeostasis;GO:0006796//phosphate-containing compound metabolic process;GO:0048592//eye morphogenesis;GO:0006935//chemotaxis;GO:0007281//germ cell development;GO:0007292//female gamete generation;GO:0007445;GO:0007399//nervous system development;GO:0008589//regulation of smoothened signaling pathway;GO:0006606//protein import into nucleus;GO:0007472//wing disc morphogenesis;GO:0019538//protein metabolic process 35055 599.48 39.24 40.845 0.0578344415457133 Up 0.162395984678378 CG5110 CG5110, isoform B K04370|1|2e-65|247|dsi:Dsim_GD24112|mitogen-activated protein kinase kinase 1 interacting protein 1 GO:0000267//cell fraction GO:0030674//protein binding, bridging - 14462779 428.00 0.01 0.24 4.58496250072116 Up 0.234975564654603 36881 3419.66 20.105 23.285 0.211846546019968 Up 0.360586448289526 CG5522 CG5522, isoform F K04349|1|6e-30|133|mdo:100014099|Ras-specific guanine nucleotide-releasing factor 1;K03099|4|4e-29|130|isc:IscW_ISCW006011|son of sevenless - - - 42145 1645.00 8.815 9.455 0.10111688862958 Up 0.160777968564258 CG7357 CG7357 K09228|1|8e-23|108|cfa:484323|KRAB domain-containing zinc finger protein - - - 40436 7252.26 91.13 116.325 0.352163214492894 Up 0.559932637696473 mub mushroom-body expressed, isoform M K13162|1|0.0|691|dme:Dmel_CG7437|poly(rC)-binding protein 2/3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 38843 678.00 0.955 0.21 -2.18511140525699 Down 0.337405890899485 CG7548 CG7548 - - - - 5740662 420.00 1.625 0.605 -1.42543267064122 Down 0.367520803064324 CG34296 CG34296 - - - - 117460 602.00 9.08 10.32 0.184678768132339 Up 0.258057059833575 TotX turandot X - GO:0044421//extracellular region part - GO:0051707//response to other organism;GO:0006952//defense response 34192 9565.94 15.735 19.56 0.31392919165381 Up 0.440892880729098 Sema-1a Sema-1a, isoform I K06842|1|0.0|1658|dya:Dyak_GE18787|semaphorin 6 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0004871//signal transducer activity;GO:0004871//signal transducer activity;GO:0004871//signal transducer activity GO:0032501//multicellular organismal process;GO:0032501//multicellular organismal process;GO:0032501//multicellular organismal process;GO:0032501//multicellular organismal process 39114 1354.00 0.96 1.95 1.02236781302845 Up 0.34546295073306 CG3222 CG3222 - - - - 42313 5278.00 4.915 3.505 -0.487776972329957 Down 0.355633337736098 Dl delta, isoform C K06051|1|0.0|1633|dme:Dmel_CG3619|delta GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development;GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development 42669 3193.00 6.6 9.585 0.538312407422335 Up 0.477975168405759 CG31156 CG31156 K11292|1|1e-14|82.8|nvi:100122614|transcription elongation factor SPT6 GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0016787//hydrolase activity GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process 36913 2634.26 44.07 41.03 -0.103117742384901 Down 0.238211596882842 CG8963 CG8963, isoform E K03260|1|9e-06|52.8|tca:656935|translation initiation factor eIF-4F - GO:0005488//binding GO:0007635//chemosensory behavior;GO:0044260;GO:0002118//aggressive behavior;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0009605//response to external stimulus 44266 1930.49 70.8 51.095 -0.47056723995041 Down 0.608572183331132 Inx3 innexin 3, isoform C - GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane GO:0022829//wide pore channel activity - 318833 3058.00 1.325 1.235 -0.101481317865884 Down 0.0693105270109629 CG33057 CG33057, isoform B K10669|1|8e-34|146|dre:503604|2'-phosphotransferase [EC:2.7.1.160] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation 32722 1923.86 39.2 32.41 -0.27441463368473 Down 0.454794611015718 CG5445 CG5445, isoform G K09442|1|6e-20|99.4|cfa:481751|SAM pointed domain-containing ETS transcription factor - - - 41069 4429.00 0.015 0.015 0 - 0.0382380134724607 CG11966 CG11966, isoform B K10519|1|1e-12|75.5|dre:567773|zinc finger and BTB domain-containing protein 48;K09229|5|1e-12|75.5|ecb:100054788|KRAB and SCAN domains-containing zinc finger protein - GO:0005488//binding - 19835236 607.00 0.465 0.55 0.242200902416628 Up 0.0815612204464404 - CG45154 - - - - 19836245 796.00 2.825 1.96 -0.527397213187342 Down 0.287445515783912 40423 1022.00 11.705 4.335 -1.43302103589018 Down 0.663353586052041 CG14565 CG14565 - - - - 44072 1272.88 103.76 94.615 -0.133109557017372 Down 0.310163782855633 ran Ran, isoform D K07936|1|5e-119|428|dya:Dyak_GE17316|GTP-binding nuclear protein Ran GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0005874//microtubule;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding GO:0065008;GO:0023060;GO:0030036//actin cytoskeleton organization;GO:0051169//nuclear transport;GO:0015031//protein transport;GO:0065008;GO:0023060;GO:0030036//actin cytoskeleton organization;GO:0051169//nuclear transport;GO:0015031//protein transport 19834743 300.00 0.3 0.81 1.43295940727611 Up 0.263703605864483 19835267 290.00 0.09 0.355 1.97982211806237 Up 0.189572051248184 38714 7109.34 13.395 15.22 0.184273777661166 Up 0.293422269185048 CG10289 CG10289, isoform D - - - - 41482 914.00 5.58 0.59 -3.24147826246735 Down 0.68778893144895 CG17404 CG17404 K01345|1|5e-28|124|xla:447029|pancreatic endopeptidase E [EC:3.4.21.70];K09632|2|2e-27|122|mcc:701625|chymotrypsin-like protease [EC:3.4.21.-];K01310|3|2e-27|122|cfa:479649|chymotrypsin [EC:3.4.21.1];K01312|5|6e-27|121|dpo:Dpse_GA11597|trypsin [EC:3.4.21.4] - - - 19835772 831.00 14.06 14.485 0.0429630901978681 Up 0.103321886144499 33271 871.00 128.26 209.415 0.707293471196058 Up 0.693369436005812 ninaA neither inactivation nor afterpotential A K01802|1|5e-139|493|dme:Dmel_CG3966|peptidylprolyl isomerase [EC:5.2.1.8];K03768|4|4e-48|191|rno:64367|peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] GO:0005626//insoluble fraction;GO:0044432//endoplasmic reticulum part;GO:0016021//integral to membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0005635//nuclear envelope GO:0008144//drug binding;GO:0016859//cis-trans isomerase activity GO:0006915//apoptotic process;GO:0006457//protein folding;GO:0046907//intracellular transport;GO:0007165//signal transduction;GO:0006726//eye pigment biosynthetic process 14462706 1407.97 8.09 7.895 -0.0352004365697407 Down 0.080768722757892 40542 1114.00 64.46 66.315 0.040931046615677 Up 0.130861180821556 vps24 vacuolar protein sorting 24 K12193|1|8e-93|340|dme:Dmel_CG9779|charged multivesicular body protein 3 - - GO:0006810//transport 32915 2455.00 11.2 11.37 0.0217335219472815 Up 0.0666688680491349 CG14196 CG14196 K08189|1|9e-16|85.9|mdo:100016751|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13;K08188|5|2e-13|78.2|ptr:468446|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 11 - - GO:0008219//cell death;GO:0003006//developmental process involved in reproduction;GO:0006810//transport 33548 1565.00 0.44 0.385 -0.192645077942396 Down 0.0653810593052437 CG15408 CG15408 K08145|1|3e-46|186|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane - GO:0006810//transport 50466 823.32 934.67 795.085 -0.233347986073001 Down 0.467045304451195 CG10570 CG10570, isoform C - - - - 5740143 526.00 15.805 13.45 -0.232774862460512 Down 0.347642319376568 CG34207 CG34207 - GO:0005737//cytoplasm - GO:0009987//cellular process;GO:0007276//gamete generation;GO:0003006//developmental process involved in reproduction 3772205 558.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 CG33772 CG33772 - - - - 37248 1070.00 0.895 0.425 -1.07442484112655 Down 0.241183463214899 CG15120 CG15120 - - - - 40273 2252.79 65.3 82.945 0.345072025062024 Up 0.551413287544578 CG32425 CG32425, isoform F - - - - 41804 2497.00 4.265 2.965 -0.524513636772287 Down 0.34708096684718 CG7262 nucleoporin 93kD-2 - - - - 2768993 654.00 0.065 1.455 4.48443562476719 Up 0.514430062078986 CG33290 CG33290 - - - - 36262 2020.00 15.4 13.38 -0.202852234940803 Down 0.315381059305244 S2P site-2 protease K07765|1|0.0|989|dme:Dmel_CG8988|S2P endopeptidase [EC:3.4.24.85] GO:0044464//cell part GO:0004175//endopeptidase activity GO:0051605 40212 1377.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG6996 CG6996, isoform C - - GO:0030247//polysaccharide binding GO:0006022 10178846 2562.28 0.065 0.175 1.42884329880387 Up 0.115473517368908 CG42661 CG42661, isoform B - GO:0031224//intrinsic to membrane - - 19834955 560.00 0.01 0.18 4.16992500144231 Up 0.1939307885352 19835954 503.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 19835674 958.50 0.125 0.185 0.565597175854225 Up 0.0792497688548408 36380 1171.00 0.04 0.185 2.20945336562895 Up 0.137036058644829 stil stand still - GO:0000785//chromatin - GO:0007548//sex differentiation;GO:0007275//multicellular organismal development 36951 883.90 149.74 97.06 -0.625510894346013 Down 0.672467309470347 Prosalpha5 proteasome alpha5 subunit, isoform B K02729|1|4e-136|483|dme:Dmel_CG10938|20S proteasome subunit alpha 5 [EC:3.4.25.1] - - - 14462851 778.00 1.97 2.65 0.427796729994185 Up 0.245674283450007 CG43638 CG43638 - - - - 37079 871.00 26.085 22.27 -0.228118875239954 Down 0.387795535596354 MED9 mediator complex subunit 9 - - - - 41300 2022.00 8.115 7.02 -0.209120064243411 Down 0.256901334037776 CG4089 CG4089 K06047|1|3e-08|60.5|spu:582881|tubulin---tyrosine ligase [EC:6.3.2.25];K05755|2|9e-06|52.4|tgu:100190205|actin related protein 2/3 complex, subunit 4 - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0043412//macromolecule modification 117406 1649.00 0.575 1.25 1.12029423371771 Up 0.293059041077797 CG32396 CG32396 K07375|1|0.0|830|dme:Dmel_CG32396|tubulin beta GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0042995//cell projection GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0050906//detection of stimulus involved in sensory perception;GO:0048729//tissue morphogenesis;GO:0002164//larval development;GO:0035264//multicellular organism growth;GO:0000226//microtubule cytoskeleton organization;GO:0043623//cellular protein complex assembly;GO:0048806//genitalia development;GO:0009790//embryo development;GO:0009612//response to mechanical stimulus 43095 5486.00 14.505 17.485 0.269567500499719 Up 0.39400343415665 tankyrase tankyrase, isoform B K10799|1|0.0|2234|dme:Dmel_CG4719|tankyrase [EC:2.4.2.30] - GO:0016763//transferase activity, transferring pentosyl groups GO:0007010//cytoskeleton organization 31228 691.92 24.065 23.615 -0.0272328878143071 Down 0.0950336811517633 tko technical knockout, isoform C K02973|1|9e-09|60.1|ame:552272|small subunit ribosomal protein S23e - - - 33339 5073.65 9.105 7.615 -0.257814980489546 Down 0.309404305904108 haf hattifattener, isoform F K13023|1|9e-20|100|mcc:707574|carboxypeptidase N regulatory subunit GO:0031224//intrinsic to membrane GO:0005488//binding - 10178969 494.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 CG42715 CG42715 - - - - 43004 868.00 10.28 10.98 0.0950377898113205 Up 0.166919825650509 PQBP1 Poly-glutamine tract binding protein 1 K12865|1|2e-25|115|aga:AgaP_AGAP011757|polyglutamine-binding protein 1 GO:0005681//spliceosomal complex GO:0005488//binding GO:0000377 12798319 1355.91 7.275 6.935 -0.0690513654720436 Down 0.110718531237617 34175 3410.39 8.07 6.62 -0.285737456470563 Down 0.318782195218597 U26 U26, isoform D K00142|1|7e-47|189|hsa:132949|aminoadipate-semialdehyde dehydrogenase [EC:1.2.1.31] - - - 42497 3171.00 7.095 6.395 -0.149858325178914 Down 0.192213710210012 CG7044 CG7044 - - - - 38292 1175.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 CG13806 CG13806 - - GO:0030247//polysaccharide binding GO:0006022 32989 625.62 711.13 761.845 0.0993841866422903 Up 0.266345264826311 CoVIb cytochrome c oxidase subunit VIb, isoform D K02267|1|3e-44|177|dme:Dmel_CG14235|cytochrome c oxidase subunit VIb [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity - 8674035 379.61 11.365 5.475 -1.05366681432931 Down 0.61989829612997 CG42489 CG42489, isoform C - - - - 32548 1450.74 157.595 130.89 -0.267866883738254 Down 0.495839387135121 MSBP membrane steroid binding protein, isoform C - GO:0016020//membrane;GO:0016020//membrane GO:0004871//signal transducer activity;GO:0005506//iron ion binding;GO:0005496//steroid binding;GO:0004871//signal transducer activity;GO:0005506//iron ion binding;GO:0005496//steroid binding - 38337 6358.28 41.35 48.3 0.224135859664498 Up 0.413188482366926 CG43955 fife, isoform G K05702|1|3e-06|55.1|api:100169483|afadin - GO:0046914//transition metal ion binding - 3771864 587.00 0.01 0.165 4.04439411935845 Up 0.184883106590939 CG33669 CG33669 - - - - 33275 3004.00 0.755 1.16 0.619576255802493 Up 0.197893276977942 GluRIIC glutamate receptor IIC K05313|1|0.0|1899|dme:Dmel_CG4226|glutamate receptor, ionotropic, invertebrate;K05203|4|8e-107|388|mmu:14807|glutamate receptor, ionotropic, kainate 3 GO:0031224//intrinsic to membrane;GO:0030313;GO:0044459//plasma membrane part;GO:0045202//synapse;GO:0044430//cytoskeletal part GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0050804//regulation of synaptic transmission 19834831 205.00 0.245 0.01 -4.61470984411521 Down 0.239499405626734 41279 3101.58 136.285 77.97 -0.805635743214697 Down 0.704101175538238 pug pugilist, isoform E K00288|1|0.0|1816|dme:Dmel_CG4067|methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0019238//cyclohydrolase activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0019238//cyclohydrolase activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0019238//cyclohydrolase activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0019238//cyclohydrolase activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559 GO:0006760//folic acid-containing compound metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0006547//histidine metabolic process;GO:0006163//purine nucleotide metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0006547//histidine metabolic process;GO:0006163//purine nucleotide metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0006547//histidine metabolic process;GO:0006163//purine nucleotide metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0006547//histidine metabolic process;GO:0006163//purine nucleotide metabolic process 12798401 812.00 0.29 0.28 -0.0506260730699681 Down 0.0419363360190199 40653 4376.91 14.65 14.98 0.0321369591491411 Up 0.0886276581693303 PEK pancreatic eIF-2alpha kinase, isoform C K08860|1|0.0|2115|dme:Dmel_CG2087|eukaryotic translation initiation factor 2-alpha kinase [EC:2.7.11.1] GO:0044432//endoplasmic reticulum part GO:0004683//calmodulin-dependent protein kinase activity;GO:0032559 GO:0006446//regulation of translational initiation;GO:0006950//response to stress;GO:0006984//ER-nucleus signaling pathway;GO:0006464//cellular protein modification process 43698 704.00 16.645 15.56 -0.0972468101540712 Down 0.193171311583675 mRpL32 mitochondrial ribosomal protein L32 - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity - 7354407 1691.73 3.895 5.14 0.400145031132209 Up 0.324758948619733 CG42362 CG42362, isoform B - - - - 318042 882.00 0.445 0.595 0.419084332341546 Up 0.112732796196011 CG32461 CG32461 - - - - 42874 1241.00 12.23 10.1 -0.276069110888229 Down 0.362930920618148 CHORD CHORD K12795|1|2e-06|53.9|nve:NEMVE_v1g107214|suppressor of G2 allele of SKP1 - - - 326264 2322.00 123.115 117.465 -0.0677755927836241 Down 0.195680887597411 CG33138 1,4-Alpha-Glucan branching enzyme K00700|1|0.0|1429|dme:Dmel_CG33138|1,4-alpha-glucan branching enzyme [EC:2.4.1.18] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process 34115 1368.00 7.83 5.865 -0.416881199262532 Down 0.39377228899749 CG8460 CG8460 - - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding GO:0006026 41292 1005.00 2.87 2.285 -0.328856571617618 Down 0.216087703077533 Desi desiccate - - - - 14462772 1897.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 31761 1544.01 14.59 18.25 0.322916580736851 Up 0.4427750627394 sni sniffer, isoform B - - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0008152//metabolic process 35059 773.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 CG15142 CG15142 - - - - 13084062 638.44 0.365 1.61 2.1410923192346 Up 0.425108968432175 CG43210 CG43210, isoform D - - - - 3771934 5316.69 8.78 7.335 -0.259423973861968 Down 0.305639941883503 cana CENP-ana, isoform C K11498|1|0.0|3595|dme:Dmel_CG33694|centromeric protein E GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 33753 3116.87 30.945 31.28 0.0155341906997114 Up 0.0782921674811782 tkv thickveins, isoform D K13579|1|0.0|974|dme:Dmel_CG14026|bone morphogenetic protein receptor type-1, invertebrate GO:0016020//membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0005770//late endosome GO:0019838//growth factor binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559;GO:0016564//transcription repressor activity;GO:0019838//growth factor binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559;GO:0016564//transcription repressor activity;GO:0019838//growth factor binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559;GO:0016564//transcription repressor activity;GO:0019838//growth factor binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559;GO:0016564//transcription repressor activity GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0019827//stem cell maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0030703//eggshell formation;GO:0060541//respiratory system development;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0019827//stem cell maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0030703//eggshell formation;GO:0060541//respiratory system development;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0019827//stem cell maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0030703//eggshell formation;GO:0060541//respiratory system development;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0019827//stem cell maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0030703//eggshell formation;GO:0060541//respiratory system development;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis 32777 2087.91 45.3 46.725 0.044683613698923 Up 0.127988376700568 Vps4 vacuolar protein sorting 4, isoform B K12196|1|0.0|771|dsi:Dsim_GD17375|vacuolar protein-sorting-associated protein 4 - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006909//phagocytosis;GO:0007010//cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity 38933 1365.00 2.21 1.385 -0.674160393342243 Down 0.289492801479329 CG7194 CG7194 - - - - 33016 1131.00 39.545 34.41 -0.200667402339614 Down 0.381290450402853 CG9577 CG9577 K12663|1|2e-168|591|dme:Dmel_CG9577|delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase [EC:5.3.3.-] GO:0044444//cytoplasmic part - - 42422 979.00 0.125 0.38 1.60407132366886 Up 0.18617091533483 CG10881 CG10881 K03248|1|2e-156|551|dme:Dmel_CG10881|translation initiation factor eIF-3 subunit 4 GO:0043234//protein complex;GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding;GO:0046914//transition metal ion binding GO:0007052//mitotic spindle organization;GO:0006412//translation 38620 1268.00 0.185 0.64 1.79054663437105 Up 0.258750495311055 blanks blanks K13194|1|7e-06|52.0|aag:AaeL_AAEL002522|double stranded RNA-specific editase 1 [EC:3.5.-.-] GO:0043229//intracellular organelle GO:0003723//RNA binding - 38738 8230.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 ndl nudel K09614|1|8e-38|160|dpo:Dpse_GA15245|corin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0001775//cell activation;GO:0007310//oocyte dorsal/ventral axis specification;GO:0051604//protein maturation;GO:0007166//cell surface receptor signaling pathway 19835542 227.00 5.375 5.7 0.0846971645752813 Up 0.11121384229296 42641 1393.00 84.01 56.81 -0.564416164099056 Down 0.645060097741382 Rpn7 regulatory particle non-ATPase 7 K03037|1|0.0|772|dsi:Dsim_GD18456|26S proteasome regulatory subunit N7 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 39884 3189.18 16.18 15.295 -0.081151500871775 Down 0.163650772685246 sina seven in absentia, isoform C K04506|1|4e-140|499|dvi:Dvir_GJ12342|E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity GO:0046532//regulation of photoreceptor cell differentiation;GO:0032446//protein modification by small protein conjugation;GO:0050953//sensory perception of light stimulus;GO:0019941//modification-dependent protein catabolic process;GO:0001752//compound eye photoreceptor fate commitment;GO:0046532//regulation of photoreceptor cell differentiation;GO:0032446//protein modification by small protein conjugation;GO:0050953//sensory perception of light stimulus;GO:0019941//modification-dependent protein catabolic process;GO:0001752//compound eye photoreceptor fate commitment 32907 1230.00 1.16 1.74 0.584962500721156 Up 0.238541804253071 CG7914 CG7914 K00326|1|1e-09|63.9|spu:580078|cytochrome-b5 reductase [EC:1.6.2.2] - GO:0003824//catalytic activity GO:0008152//metabolic process 32606 1808.54 50.34 42.43 -0.246620537870243 Down 0.444723286223749 CG4239 CG4239, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005216//ion channel activity;GO:0005216//ion channel activity;GO:0005216//ion channel activity GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport 31567 1465.00 88.35 57.365 -0.623059358281916 Down 0.661009113723418 Rpt4 regulatory particle triple-A ATPase 4 K03064|1|0.0|773|dya:Dyak_GE16469|26S proteasome regulatory subunit T4 - - - 35678 2222.98 16.645 14.105 -0.238882204554692 Down 0.360091137234183 CG1620 CG1620, isoform C K11660|1|1e-09|65.9|mdo:100012010|metastasis-associated protein MTA - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 39132 1979.30 176.685 155.895 -0.180604907415528 Down 0.39423457931581 CG6767 CG6767, isoform J K00948|1|0.0|772|dya:Dyak_GE21218|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] - GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778 GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009124//nucleoside monophosphate biosynthetic process 5740215 639.00 3.45 4.815 0.480939436177928 Up 0.348533879276185 CG13177 CG13177, isoform B - - - - 32274 1371.88 37.12 36.65 -0.0183835121063979 Down 0.0822216351868974 REG REG, isoform B K06698|1|4e-136|484|dme:Dmel_CG1591|proteasome activator subunit 3 (PA28 gamma) GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0022624//proteasome accessory complex GO:0061135 GO:0010498//proteasomal protein catabolic process;GO:0000377 33290 1767.00 22.215 25.965 0.225034084077791 Up 0.387003037907806 Iris iris - - - - 35161 1390.00 0.45 0.185 -1.28239973070072 Down 0.17910447761194 CG15169 CG15169 - - - - 38764 827.00 1.09 0.865 -0.333556097140201 Down 0.13033284902919 CG10063 CG10063 - - - - 40052 1317.49 4.975 6.665 0.421908349657962 Up 0.371912561088364 dysb dysbindin ortholog, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0044446//intracellular organelle part;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005488//binding GO:0009987//cellular process;GO:0016043//cellular component organization 32189 1980.00 0.1 0.09 -0.15200309344505 Down 0.045238409721305 Ir11a ionotropic receptor 11a - GO:0030313 - GO:0051234//establishment of localization 33251 1426.00 1.715 0.1 -4.10013667128545 Down 0.532261260071325 Gr21a gustatory receptor 21a, isoform B K08471|1|1e-36|154|dme:Dmel_CG14979|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0010035//response to inorganic substance;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38146 1805.00 39.04 35.075 -0.154509949055625 Down 0.315447100779289 Rac1 Rac1, isoform B K04392|1|1e-108|394|dvi:Dvir_GJ13209|Ras-related C3 botulinum toxin substrate 1 GO:0048770;GO:0042995//cell projection;GO:0005884//actin filament;GO:0005626//insoluble fraction;GO:0012505//endomembrane system;GO:0030427//site of polarized growth;GO:0019898//extrinsic to membrane;GO:0031252//cell leading edge;GO:0044297//cell body GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding GO:0007017//microtubule-based process;GO:0001894//tissue homeostasis;GO:0010591//regulation of lamellipodium assembly;GO:0031589//cell-substrate adhesion;GO:0045806//negative regulation of endocytosis;GO:0007409//axonogenesis;GO:0001736//establishment of planar polarity;GO:0050905//neuromuscular process;GO:0048588//developmental cell growth;GO:0008283//cell proliferation;GO:0019094//pole plasm mRNA localization;GO:0042051//compound eye photoreceptor development;GO:0007392;GO:0007266//Rho protein signal transduction;GO:0021795//cerebral cortex cell migration;GO:0007297//ovarian follicle cell migration;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0006935//chemotaxis;GO:0006917//induction of apoptosis;GO:0042386//hemocyte differentiation;GO:0006970//response to osmotic stress;GO:0030041//actin filament polymerization;GO:0034331;GO:0006275//regulation of DNA replication;GO:0006952//defense response;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0002252;GO:0002682//regulation of immune system process;GO:0055002//striated muscle cell development;GO:0021843;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0042743//hydrogen peroxide metabolic process;GO:0009207;GO:0000768//syncytium formation by plasma membrane fusion;GO:0033554//cellular response to stress;GO:0000165//MAPK cascade;GO:0006909//phagocytosis;GO:0007424//open tracheal system development;GO:0007431//salivary gland development 19835968 1049.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 34572 2954.00 0.49 0.48 -0.0297473433940521 Down 0.0416391493858143 spz4 spatzle 4 - - - - 41017 6333.00 3.79 4.92 0.376460467168148 Up 0.307059833575485 CG42796 5-hydroxytryptamine (serotonin) receptor 2B, isoform F K04159|1|3e-45|184|mdo:100011052|5-hydroxytryptamine (serotonin) receptor 2C GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0023060;GO:0007166//cell surface receptor signaling pathway 34815 1335.00 16.63 14.05 -0.24321803817898 Down 0.36167613261128 nimB5 nimrod B5, isoform C K06252|1|5e-17|89.0|bta:282654|tenascin - - - 34836 774.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 Send2 spermathecal endopeptidase 2 K01312|1|8e-43|173|dpo:Dpse_GA14937|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40710 3501.00 14.175 15.47 0.126124461619444 Up 0.231277242108044 Madm MLF1-adaptor molecule K08875|1|0.0|1058|dme:Dmel_CG1098|nuclear receptor-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0016301//kinase activity;GO:0032559 GO:0032535//regulation of cellular component size;GO:0048193//Golgi vesicle transport;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process 38062 3219.00 7.05 7.38 0.0659975587742401 Up 0.109298639545635 CG6905 cell division cycle 5 ortholog, isoform B K12860|1|0.0|1533|dme:Dmel_CG6905|pre-mRNA-splicing factor CDC5/CEF1 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0000377;GO:0010468//regulation of gene expression;GO:0000377 39774 2314.00 3.265 2.83 -0.206280938714548 Down 0.163617751948223 l(3)72Dn lethal (3) 72Dn, isoform B K02084|1|4e-07|57.0|oaa:100073402|apoptotic protease-activating factor;K12602|2|3e-06|54.3|api:100164117|WD repeat-containing protein 61 - - - 43227 1184.00 2.75 2.45 -0.166649869409451 Down 0.131158367454762 IntS12 integrator 12 K13149|1|1e-97|356|dme:Dmel_CG5491|integrator complex subunit 12 - GO:0046872//metal ion binding - 38330 1687.70 0.495 0.525 0.084888897586513 Up 0.0499273543785497 CG1246 CG1246, isoform E - - - - 36464 2375.88 47.275 25.88 -0.869239840844616 Down 0.687755910711927 CG4670 CG4670, isoform B K10758|1|1e-71|271|dre:100004382|thiol oxidase [EC:1.8.3.2] - GO:0016972//thiol oxidase activity GO:0008152//metabolic process;GO:0019725//cellular homeostasis 32661 5679.14 23.285 21.63 -0.106367216858349 Down 0.226126007132479 if inflated, isoform F K06584|1|1e-117|425|mdo:100027090|integrin alpha 8;K06487|2|3e-115|417|mdo:100028127|integrin alpha V;K06484|3|4e-115|417|dre:386787|integrin alpha 5 GO:0043232;GO:0005887//integral to plasma membrane;GO:0043232;GO:0005887//integral to plasma membrane;GO:0043232;GO:0005887//integral to plasma membrane;GO:0043232;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0007166//cell surface receptor signaling pathway;GO:0007424//open tracheal system development;GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0010669//epithelial structure maintenance;GO:0051235;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006935//chemotaxis;GO:0048565//digestive tract development;GO:0010927;GO:0007431//salivary gland development;GO:0007606//sensory perception of chemical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007424//open tracheal system development;GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0010669//epithelial structure maintenance;GO:0051235;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006935//chemotaxis;GO:0048565//digestive tract development;GO:0010927;GO:0007431//salivary gland development;GO:0007606//sensory perception of chemical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007424//open tracheal system development;GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0010669//epithelial structure maintenance;GO:0051235;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006935//chemotaxis;GO:0048565//digestive tract development;GO:0010927;GO:0007431//salivary gland development;GO:0007606//sensory perception of chemical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007424//open tracheal system development;GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0010669//epithelial structure maintenance;GO:0051235;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006935//chemotaxis;GO:0048565//digestive tract development;GO:0010927;GO:0007431//salivary gland development;GO:0007606//sensory perception of chemical stimulus 59142 1487.00 0.055 0.09 0.710493382805015 Up 0.0690133403777572 CG18746 CG18746 - - - - 42464 564.00 564.575 535.18 -0.0771410434825304 Down 0.225069343547748 RpS20 ribosomal protein S20 K02969|1|1e-63|241|dme:Dmel_CG15693|small subunit ribosomal protein S20e GO:0015935//small ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0010467//gene expression 33131 3258.01 13.64 13.535 -0.0111487568092087 Down 0.0555739004094571 CG14614 wings apart, isoform D K11805|1|0.0|722|dpe:Dper_GL13429|WD repeat-containing protein 68 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004468//lysine N-acetyltransferase activity GO:0032501//multicellular organismal process;GO:0009888//tissue development;GO:0032446//protein modification by small protein conjugation 36146 1664.85 97.855 122.41 0.323003946650442 Up 0.539756967375512 CG7686 CG7686, isoform B - - - - 35004 4686.04 26.69 33.985 0.34859881733483 Up 0.513010170387003 CG17912 CG17912, isoform G - GO:0044464//cell part;GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 42934 2896.15 56.695 48.03 -0.239285699197511 Down 0.440034341566504 atl atlastin, isoform C - GO:0005789//endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0048741//skeletal muscle fiber development;GO:0048638//regulation of developmental growth;GO:0048284//organelle fusion;GO:0007019//microtubule depolymerization;GO:0048741//skeletal muscle fiber development;GO:0048638//regulation of developmental growth;GO:0048284//organelle fusion;GO:0007019//microtubule depolymerization 5740633 1722.00 0.29 0.18 -0.68805599368526 Down 0.103652093514727 nvd neverland - - GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0003824//catalytic activity GO:0006694//steroid biosynthetic process;GO:0009653//anatomical structure morphogenesis;GO:0040007//growth;GO:0002164//larval development 36319 5896.00 9.37 8.885 -0.0766772716305086 Down 0.132908466516973 CG8858 CG8858 K11886|1|0.0|3627|dme:Dmel_CG8858|proteasome component ECM29 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0009057//macromolecule catabolic process 31419 1868.00 0.435 0.145 -1.58496250072116 Down 0.198916919825651 CG6927 CG6927 K05195|1|3e-45|183|dre:192124|glycine receptor alpha-3;K05193|2|9e-45|181|dre:30676|glycine receptor alpha-1 GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0005237//inhibitory extracellular ligand-gated ion channel activity GO:0006909//phagocytosis 45328 2451.00 0.205 0.48 1.22741049610307 Up 0.18187821952186 sens senseless K10631|1|4e-51|203|nvi:100116176|E3 ubiquitin-protein ligase Topors [EC:6.3.2.19];K09223|2|7e-48|192|spu:589099|growth factor independent 1 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0008134//transcription factor binding GO:0042461//photoreceptor cell development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043704//photoreceptor cell fate specification;GO:0006915//apoptotic process;GO:0001709//cell fate determination;GO:0006935//chemotaxis 38233 1242.00 0.465 0.725 0.640750278906903 Up 0.156155065381059 CG12020 CG12020 K09519|1|1e-46|187|bfo:BRAFLDRAFT_114430|DnaJ homolog subfamily B member 13 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process 31506 3578.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG3108 CG3108 K08637|1|4e-67|257|mcc:702856|carboxypeptidase A4 [EC:3.4.17.-];K08779|2|8e-67|256|dre:246092|carboxypeptidase A1 [EC:3.4.17.1];K01290|4|4e-65|250|dgr:Dgri_GH10071|carboxypeptidase A, invertebrate [EC:3.4.17.-] - - - 12798523 1563.00 111.09 137.55 0.308227184310787 Up 0.53232730154537 8673972 600.00 0.14 0.08 -0.807354922057604 Down 0.0821225729758288 CG42531 CG42531, isoform B - - - - 33798 1550.25 1.765 2.02 0.194687109480614 Up 0.121648395192181 CG7236 CG7236, isoform E K08824|1|0.0|773|dya:Dyak_GE25570|cyclin-dependent kinase-like [EC:2.7.11.22] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 38343 1296.00 21.125 20.675 -0.0310640119982721 Down 0.0950336811517633 CG12093 CG12093 - - - - 12798439 936.00 0.255 0.28 0.134929580086109 Up 0.0538238013472461 33167 2551.00 15.07 16.835 0.159784304229822 Up 0.277043983621714 Nhe1 Na[+]/H[+] hydrogen exchanger 1 K03316|1|1e-157|557|spu:578765|monovalent cation:H+ antiporter, CPA1 family;K12041|2|7e-70|265|mcc:710429|solute carrier family 9, member 6 GO:0031224//intrinsic to membrane GO:0005451//monovalent cation:hydrogen antiporter activity GO:0055067;GO:0030001//metal ion transport 31449 2744.07 1.63 1.065 -0.614018534005239 Down 0.23586712455422 Mcm3 minichromosome maintenance 3, isoform B K02541|1|0.0|1572|dme:Dmel_CG4206|minichromosome maintenance protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0032993//protein-DNA complex GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0006261//DNA-dependent DNA replication 34720 1420.00 3.705 4.315 0.219887016873121 Up 0.198157442874125 CG5705 CG5705 K02835|1|0.0|721|dme:Dmel_CG5705|peptide chain release factor RF-1 GO:0044424//intracellular part GO:0003747//translation release factor activity GO:0006412//translation 39769 582.00 26.17 28.635 0.129865679077059 Up 0.27189274864615 l(3)72Dh TRAPP subunit 20 ortholog - GO:0044464//cell part - GO:0048193//Golgi vesicle transport;GO:0050658//RNA transport 39095 3375.03 6.915 6.88 -0.0073206864483963 Down 0.0472856954167217 phol pleiohomeotic like, isoform B K09201|1|0.0|1161|dme:Dmel_CG3445|transcription factor YY GO:0000790//nuclear chromatin;GO:0005700//polytene chromosome GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003682//chromatin binding GO:0016458//gene silencing 39935 2130.00 0.055 0.01 -2.4594316186373 Down 0.0874058908994849 tap target of poxn K09081|1|4e-20|100|dre:30239|neurogenin 1;K09082|2|5e-20|99.8|xla:398061|neurogenin 2 GO:0043231//intracellular membrane-bounded organelle - GO:0048513//organ development;GO:0006355//regulation of transcription, DNA-dependent 43508 4554.69 17.3 18.945 0.131045101984621 Up 0.246730947034738 yata yata, isoform B K08876|1|0.0|1413|dme:Dmel_CG1973|SCY1-like - GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process 36601 2475.00 9.51 11.385 0.259617045276059 Up 0.337471932373531 Dh44-R1 diuretic hormone 44 receptor 1 K04578|1|0.0|966|dme:Dmel_CG8422|corticotropin releasing hormone receptor 1 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0005179//hormone activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 34893 979.13 6.47 5.985 -0.112414465049006 Down 0.148131026284507 l(2)35Cc lethal (2) 35Cc, isoform B - GO:0043234//protein complex;GO:0044430//cytoskeletal part GO:0005515//protein binding GO:0031023//microtubule organizing center organization;GO:0044267//cellular protein metabolic process;GO:0003006//developmental process involved in reproduction 40186 899.00 271.155 288.715 0.090528290430887 Up 0.242999603751156 Nca neurocalcin, isoform A K13764|1|7e-55|213|bta:281447|recoverin - GO:0046872//metal ion binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor GO:0016310//phosphorylation 318053 1904.10 48.99 35.325 -0.471797731061549 Down 0.595297847047946 CG32495 CG32495, isoform I K01920|1|0.0|657|dme:Dmel_CG6835|glutathione synthase [EC:6.3.2.3] - GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process 12798248 2341.20 28.82 30.695 0.0909333343275896 Up 0.207799498084797 3772566 1640.97 2.255 1.6 -0.495055528368019 Down 0.248315942411835 CG11714 CG11714, isoform C K10478|1|8e-07|55.5|tgu:100223888|BTB/POZ domain-containing protein 3/6;K10523|3|1e-06|54.7|xtr:394599|speckle-type POZ protein - GO:0005488//binding - 40885 756.00 0.835 2.16 1.37118320968942 Up 0.412429005415401 CG17944 CG17944 - - - - 38696 1067.00 2.505 5.135 1.03555367312299 Up 0.512085589750363 CG10469 CG10469 K01310|1|4e-29|128|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K09634|2|5e-28|125|gga:427988|transmembrane protease, serine 3 [EC:3.4.21.-];K01340|3|6e-28|124|ssc:397389|tryptase [EC:3.4.21.59];K01362|5|8e-28|124|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39403 1981.59 40.11 38.835 -0.0466045001932416 Down 0.142088231409325 CG4300 CG4300, isoform D K00802|1|0.0|738|dse:Dsec_GM24668|spermine synthase [EC:2.5.1.22] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0006596//polyamine biosynthetic process;GO:0006596//polyamine biosynthetic process 41913 5400.45 29.585 39.235 0.407275305113017 Up 0.556168273675868 alpha-Man-IIb alpha-Man-IIb, isoform C K01191|1|0.0|2382|dme:Dmel_CG4606|alpha-mannosidase [EC:3.2.1.24] - - - 246531 965.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 CG30288 CG30288 K01362|1|3e-26|118|dme:Dmel_CG4920| [EC:3.4.21.-];K01316|3|1e-24|113|tgu:100220466|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K01312|4|4e-23|108|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01324|5|2e-22|106|rno:25048|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33953 2118.37 302.075 267.335 -0.176258059971824 Down 0.398395192180689 nrv2 nervana 2, isoform G K01540|1|1e-175|616|dme:Dmel_CG9261|sodium/potassium-transporting ATPase subunit beta GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane GO:0008556//potassium-transporting ATPase activity;GO:0008556//potassium-transporting ATPase activity;GO:0008556//potassium-transporting ATPase activity;GO:0008556//potassium-transporting ATPase activity;GO:0008556//potassium-transporting ATPase activity GO:0007043//cell-cell junction assembly;GO:0035151//regulation of tube size, open tracheal system;GO:0009206;GO:0021782//glial cell development;GO:0030001//metal ion transport;GO:0007043//cell-cell junction assembly;GO:0035151//regulation of tube size, open tracheal system;GO:0009206;GO:0021782//glial cell development;GO:0030001//metal ion transport;GO:0007043//cell-cell junction assembly;GO:0035151//regulation of tube size, open tracheal system;GO:0009206;GO:0021782//glial cell development;GO:0030001//metal ion transport;GO:0007043//cell-cell junction assembly;GO:0035151//regulation of tube size, open tracheal system;GO:0009206;GO:0021782//glial cell development;GO:0030001//metal ion transport;GO:0007043//cell-cell junction assembly;GO:0035151//regulation of tube size, open tracheal system;GO:0009206;GO:0021782//glial cell development;GO:0030001//metal ion transport 31350 8938.70 18.86 22.755 0.270853910293093 Up 0.417646281865011 lva lava lamp, isoform D K11498|1|4e-09|65.9|mcc:711186|centromeric protein E;K04648|2|5e-09|65.5|bfo:BRAFLDRAFT_126882|dynactin 1;K06102|3|5e-09|65.5|ssc:100157963|cingulin;K12478|5|5e-09|65.5|bta:516259|early endosome antigen 1 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding GO:0031345//negative regulation of cell projection organization;GO:0007275//multicellular organismal development;GO:0051649//establishment of localization in cell 31380 3429.35 52.68 62 0.235012869905086 Up 0.443039228635583 CG3556 CG3556, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0051180//vitamin transport 37972 1126.00 0.075 0.345 2.20163386116965 Up 0.197959318451988 CG3611 CG3611, isoform C - - - - 42526 1059.24 20.715 23.96 0.209952087809579 Up 0.361610091137234 CG5919 CG5919, isoform B K01823|1|2e-149|528|dme:Dmel_CG5919|isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2] - GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds GO:0006720//isoprenoid metabolic process;GO:0006720//isoprenoid metabolic process 42832 2162.73 353.395 502.02 0.506463212820649 Up 0.650937788931449 Gdh glutamate dehydrogenase, isoform F K00261|1|0.0|1101|dme:Dmel_CG5320|glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] GO:0031980;GO:0031980;GO:0031980 GO:0005515//protein binding;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor GO:0046692//sperm competition;GO:0006103//2-oxoglutarate metabolic process;GO:0006734//NADH metabolic process;GO:0045333//cellular respiration;GO:0006519;GO:0046692//sperm competition;GO:0006103//2-oxoglutarate metabolic process;GO:0006734//NADH metabolic process;GO:0045333//cellular respiration;GO:0006519;GO:0046692//sperm competition;GO:0006103//2-oxoglutarate metabolic process;GO:0006734//NADH metabolic process;GO:0045333//cellular respiration;GO:0006519 39139 1073.00 2.355 2.955 0.327431070564749 Up 0.219852067098138 CG14174 CG14174 - - - - 326178 1293.94 4.875 6.5 0.415037499278844 Up 0.365176330735702 CG31948 CG31948, isoform B - - - - 33161 3922.28 17.465 17.47 0.000412965521894814 Up 0.0382380134724607 dbr debra, isoform F - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 37832 1701.00 104.595 89.165 -0.230264463180348 Down 0.447860256240919 CG3907 CG3907, isoform B K10352|1|7e-07|55.8|tgu:100230210|myosin heavy chain;K09291|3|4e-06|53.1|gga:424457|nucleoprotein TPR - - - 39472 1065.00 0.15 0.74 2.30256277002043 Up 0.303361511028926 CG11263 CG11263, isoform B - GO:0044464//cell part;GO:0044464//cell part GO:0004527//exonuclease activity;GO:0005488//binding;GO:0004527//exonuclease activity;GO:0005488//binding GO:0034641//cellular nitrogen compound metabolic process;GO:0034641//cellular nitrogen compound metabolic process 19836250 1729.97 2.22 1.755 -0.339088646045545 Down 0.192940166424515 - Cyp6a16, isoform C - - - - 39454 4047.24 43.635 44.3 0.0218209016209181 Up 0.0854576674151367 Atg1 Autophagy-specific gene 1, isoform B K08269|1|0.0|1394|dme:Dmel_CG10967|unc51-like kinase [EC:2.7.11.1] - GO:0008092//cytoskeletal protein binding;GO:0004672//protein kinase activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0004672//protein kinase activity;GO:0032559 GO:0044248//cellular catabolic process;GO:0009968//negative regulation of signal transduction;GO:0016049//cell growth;GO:0007416//synapse assembly;GO:0007552//metamorphosis;GO:0051969;GO:0010970//microtubule-based transport;GO:0006464//cellular protein modification process;GO:0044248//cellular catabolic process;GO:0009968//negative regulation of signal transduction;GO:0016049//cell growth;GO:0007416//synapse assembly;GO:0007552//metamorphosis;GO:0051969;GO:0010970//microtubule-based transport;GO:0006464//cellular protein modification process 2768877 2477.93 16.405 13.68 -0.262067363632522 Down 0.379078061022322 CG5541 CG5541, isoform B - - - - 3772241 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 36031 2279.39 57.185 56.44 -0.0189187803346085 Down 0.0867784968960507 Etf-QO electron transfer flavoprotein-ubiquinone oxidoreductase, isoform B K00311|1|0.0|1254|dme:Dmel_CG12140|electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1] GO:0015630//microtubule cytoskeleton;GO:0031304//intrinsic to mitochondrial inner membrane GO:0048038//quinone binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor GO:0006091//generation of precursor metabolites and energy;GO:0006635//fatty acid beta-oxidation;GO:0051234//establishment of localization;GO:0006950//response to stress 38921 559.00 0.305 0.18 -0.760812336120574 Down 0.109926033549069 CG13674 CG13674, isoform B - - - - 318166 704.00 0.665 1.255 0.916261118449582 Up 0.263505481442346 CG32713 CG32713, isoform B - - - - 38681 1078.00 0.045 0.045 0 - 0.0382380134724607 CG6462 CG6462 K01310|1|2e-36|152|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|4|1e-32|140|dme:Dmel_CG31039| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 3354922 1223.27 92.68 39.22 -1.24066850867267 Down 0.740126799630168 CG40198 CG40198, isoform C - - - - 38655 1139.18 29.82 34.375 0.205079455903304 Up 0.383073570202087 CG5537 CG5537, isoform C K00761|1|4e-118|424|dme:Dmel_CG5537|uracil phosphoribosyltransferase [EC:2.4.2.9] GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity GO:0055086//nucleobase-containing small molecule metabolic process 36286 4675.78 12.105 12.58 0.0555288428803525 Up 0.121186104873861 pds5 pds5, isoform B K11267|1|0.0|2302|dme:Dmel_CG17509|sister chromatid cohesion protein PDS5 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome - GO:0007059//chromosome segregation;GO:0051276//chromosome organization 19835895 466.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 45830 3053.37 31.705 31.265 -0.020161859594443 Down 0.0815281997094175 bur burgundy, isoform C K01951|1|0.0|1353|dme:Dmel_CG9242|GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] - GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0032559 GO:0006935//chemotaxis;GO:0009064//glutamine family amino acid metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0016570//histone modification 31250 946.00 0.415 0.805 0.955877446767692 Up 0.214106458856162 CG2652 CG2652 K11341|1|3e-07|55.8|smm:Smp_070760|YEATS domain-containing protein 4 - - - 41607 1399.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 snk snake, isoform C K01312|1|1e-36|154|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4];K01320|2|1e-33|144|tgu:100223776|coagulation factor VII [EC:3.4.21.21];K09641|3|7e-33|141|ptr:471225|transmembrane protease, serine 11D [EC:3.4.21.-];K01324|4|2e-32|140|gga:422723|plasma kallikrein [EC:3.4.21.34] - - - 41192 1410.00 61.31 61.15 -0.00376990589401834 Down 0.0462620525690133 CG8417 CG8417 K01809|1|0.0|794|dme:Dmel_CG8417|mannose-6-phosphate isomerase [EC:5.3.1.8] - GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0046914//transition metal ion binding GO:0044238//primary metabolic process 37342 3660.00 5.18 4.315 -0.263591538507599 Down 0.243660018491613 Lrt Leucine-rich tendon-specific protein, isoform C K13023|1|5e-23|110|mcc:707574|carboxypeptidase N regulatory subunit;K06838|5|1e-22|108|cfa:486818|slit 1 - - - 34094 1265.00 1.58 0.105 -3.91146332539834 Down 0.50845330867785 CG7367 CG7367, isoform D K01046|1|3e-36|152|oaa:100079831|triacylglycerol lipase [EC:3.1.1.3];K01059|2|1e-35|151|dpo:Dpse_GA19044|lipoprotein lipase [EC:3.1.1.34] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:0006909//phagocytosis;GO:0044238//primary metabolic process;GO:0006909//phagocytosis 41037 1619.85 3.015 4.15 0.460953334334202 Up 0.319079381851803 CG8136 CG8136, isoform D - - - - 37068 2795.05 22.595 23.53 0.0584977635532942 Up 0.147602694492141 Hsf heat shock factor, isoform D K09418|1|0.0|1203|dme:Dmel_CG5748|heat shock transcription factor, invertebrate - - - 41209 5551.54 14.19 13.31 -0.0923640181486598 Down 0.17203803988905 FBX011 FBX011 ortholog, isoform B K10297|1|0.0|1771|dme:Dmel_CG9461|F-box protein 11 - GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding - 37998 1726.00 77.545 81.23 0.0669788832062215 Up 0.191850482102761 CG2736 CG2736 K12384|1|4e-25|116|dre:192340|lysosome membrane protein 2;K13885|2|5e-24|112|gga:416814|scavenger receptor class B, member 1 GO:0016021//integral to membrane;GO:0044444//cytoplasmic part - GO:0006950//response to stress;GO:0009987//cellular process 318825 530.31 34.175 49.69 0.540014204056688 Up 0.621615374455158 mRpL27 mitochondrial ribosomal protein L27, isoform C - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 14462450 1239.00 11.58 8.835 -0.39033321343762 Down 0.433958525954299 42585 1316.00 2.305 2.935 0.348593752680715 Up 0.227909126931713 CG6332 CG6332 - - - - 33575 2275.00 0.645 1.24 0.942969054963621 Up 0.266774534407608 CG8851 CG8851, isoform C K10352|1|7e-13|76.3|cin:100176948|myosin heavy chain;K10381|3|2e-11|71.6|dre:324023|desmoplakin - - - 32818 2331.00 5.8 6.115 0.0762995985124524 Up 0.11121384229296 por porcupine, isoform C K00181|1|0.0|833|dme:Dmel_CG6205|porcupine GO:0016020//membrane GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups GO:0006464//cellular protein modification process;GO:0035466 42185 1335.00 579.37 583.145 0.00936967337599199 Up 0.0706973979659226 Mdh2 malate dehydrogenase 2 K00026|1|0.0|654|dse:Dsec_GM15290|malate dehydrogenase [EC:1.1.1.37] - - - 40996 2494.02 39.86 32.935 -0.275320160052917 Down 0.464238541804253 DppIII dipeptidyl aminopeptidase III, isoform C K01277|1|0.0|1476|dme:Dmel_CG7415|dipeptidyl-peptidase III [EC:3.4.14.4] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 46059 2043.98 32.085 29.96 -0.0988613594274495 Down 0.225795799762251 Sply Sphingosine-1-phosphate lyase, isoform B K01634|1|0.0|1112|dme:Dmel_CG8946|sphinganine-1-phosphate aldolase [EC:4.1.2.27] GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0031227//intrinsic to endoplasmic reticulum membrane GO:0048037//cofactor binding;GO:0016832//aldehyde-lyase activity;GO:0048037//cofactor binding;GO:0016832//aldehyde-lyase activity GO:0043436;GO:0006665//sphingolipid metabolic process;GO:0043436;GO:0006665//sphingolipid metabolic process 42135 3135.93 1.38 1.5 0.120294233717712 Up 0.0806696605468234 TyrRII tyramine receptor II, isoform D K04135|1|3e-44|180|api:100163236|adrenergic receptor alpha-1A;K04155|3|6e-23|109|gga:769107|5-hydroxytryptamine (serotonin) receptor 1D - - - 37159 1073.00 0.145 0.53 1.86993945943563 Up 0.235503896446969 CG17821 CG17821 K00680|1|1e-54|213|dme:Dmel_CG8534| [EC:2.3.1.-];K10249|5|5e-42|171|dre:393769|elongation of very long chain fatty acids protein 4 - - - 34329 778.75 757.68 757.43 -0.000476102413020179 Down 0.0466252806762647 RpL13 ribosomal protein L13, isoform C K02873|1|2e-109|395|dme:Dmel_CG4651|large subunit ribosomal protein L13e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 50305 687.26 71.44 17.275 -2.0480463698456 Down 0.778860124157971 CG8012 CG8012, isoform B - - - - 37349 1633.00 1.25 1.725 0.464668267003444 Up 0.2085259542993 CG13442 CG13442 K10658|1|2e-15|84.0|nve:NEMVE_v1g25775|E3 ubiquitin-protein ligase MARCH3 [EC:6.3.2.19];K10656|4|4e-14|79.7|dwi:Dwil_GK17579|E3 ubiquitin-protein ligase MARCH1/8 [EC:6.3.2.19] - - - 12797933 621.00 0.325 0.01 -5.02236781302845 Down 0.285233126403381 36429 1796.00 0.11 0.12 0.125530882083859 Up 0.0444459120327566 CG3884 CG44251, isoform B - - - - 19835997 267.00 0.525 0.01 -5.71424551766612 Down 0.371153084136838 41922 1773.00 4.07 6.675 0.713739042308669 Up 0.47926297714965 CG4546 CG4546 K00934|1|0.0|894|dme:Dmel_CG4546|arginine kinase [EC:2.7.3.3];K00933|2|8e-85|314|ame:550932|creatine kinase [EC:2.7.3.2] - - - 32203 817.76 42.395 23.32 -0.862326337085897 Down 0.681085721833311 Cpr11B cuticular protein 11B, isoform B - - GO:0042302//structural constituent of cuticle - 39284 5838.35 63.895 72.2 0.17629579729286 Up 0.376700567956677 chrb charybde, isoform E K08270|1|3e-09|65.1|dre:378866|DNA-damage-inducible transcript 4 GO:0044424//intracellular part - GO:0001700//embryonic development via the syncytial blastoderm;GO:0006950//response to stress;GO:0009966//regulation of signal transduction;GO:0012501//programmed cell death;GO:0040008//regulation of growth 44227 2472.57 130.705 110.005 -0.248745231858806 Down 0.472757891956148 Fatp fatty acid (long chain) transport protein, isoform E K08745|1|0.0|1352|dme:Dmel_CG7400|solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0015245//fatty acid transporter activity;GO:0015245//fatty acid transporter activity;GO:0015245//fatty acid transporter activity GO:0015908//fatty acid transport;GO:0015908//fatty acid transport;GO:0015908//fatty acid transport 43317 5687.10 12.7 17.335 0.448859339543305 Up 0.51159027869502 Tusp tusp, isoform G K09448|1|4e-15|85.1|cfa:481758|TEA domain family member 1/3/4 - - - 45848 503.00 12.825 13.215 0.0432175991471535 Up 0.101175538238013 e(y)2 enhancer of yellow 2 K11368|1|7e-42|169|dme:Dmel_CG15191|enhancer of yellow 2 transcription factor GO:0044427//chromosomal part;GO:0070461//SAGA-type complex;GO:0005635//nuclear envelope GO:0003712//transcription cofactor activity;GO:0019904//protein domain specific binding;GO:0031490//chromatin DNA binding GO:0006406//mRNA export from nucleus;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006342//chromatin silencing;GO:0006325//chromatin organization 37982 1165.00 0.62 0.69 0.154328146391294 Up 0.0705653150178312 CG9083 CG9083 - - - - 40282 950.00 24.355 27.735 0.187489742284904 Up 0.348566900013208 CG4858 CG4858 K03593|1|2e-36|152|hmg:100198387|ATP-binding protein involved in chromosome partitioning - GO:0051536//iron-sulfur cluster binding;GO:0016462//pyrophosphatase activity;GO:0043169//cation binding;GO:0032559 - 33174 1446.83 26.72 27.605 0.0470095933178869 Up 0.133271694624224 CG31974 CG31974, isoform D - - - - 38447 1479.00 321.905 301.325 -0.0953146118700294 Down 0.263406419231277 Scsalpha succinyl coenzyme A synthetase alpha subunit, isoform B K01899|1|5e-164|577|dya:Dyak_GE21380|succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex;GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0009060//aerobic respiration;GO:0009060//aerobic respiration 33207 1972.00 33.855 27.335 -0.308619543713409 Down 0.482697133800026 Ent1 equilibrative nucleoside transporter 1, isoform C K03323|1|0.0|892|dme:Dmel_CG11907|equilibrative nucleoside transporter, ENT family GO:0044464//cell part;GO:0044464//cell part GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0051234//establishment of localization;GO:0051234//establishment of localization 36327 1544.49 2.2 3.67 0.738276539318553 Up 0.390767401928411 CG13168 CG13168, isoform D - - - - 33178 1699.00 2.115 2.08 -0.0240741349788576 Down 0.0488046493197728 CG3709 CG3709 - - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0009451//RNA modification 43315 5704.80 17.64 18.82 0.093416067171016 Up 0.187590807026813 dsd distracted, isoform C K05637|1|2e-13|79.3|ecb:100059860|laminin, alpha 1 GO:0031224//intrinsic to membrane GO:0005488//binding - 47894 1798.00 5.4 6.05 0.163975735111126 Up 0.188449346189407 hbn homeobrain K09452|1|2e-26|120|dre:30657|homeobox protein aristaless-related - GO:0005488//binding GO:0006350 34410 1649.00 1.845 1.35 -0.450661409009565 Down 0.212290318319905 CG5096 CG5096 K06260|1|5e-20|99.4|xla:446839|platelet glycoprotein V - GO:0005488//binding - 33446 596.12 18.035 14.665 -0.298422352030615 Down 0.423689076740193 CG15394 CG15394, isoform D - - - - 36068 3329.00 3.94 4.07 0.046833164809871 Up 0.0716219786025624 CG18011 CG18011 K09228|1|2e-39|165|ecb:100060075|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0051540 - 19835644 801.00 0.105 0.06 -0.807354922057604 Down 0.07657508915599 19834870 350.00 0.25 0.145 -0.785875194647152 Down 0.101637828556333 12798580 341.00 0.64 0.315 -1.02272007650008 Down 0.195879012019548 43512 1154.00 0.475 0.385 -0.303069067636046 Down 0.0869105798441421 sro shroud K00019|1|0.0|637|dme:Dmel_CG12068|3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] - GO:0003824//catalytic activity GO:0008152//metabolic process 36294 782.00 0.455 1.29 1.50343261522456 Up 0.337769119006736 CG13186 CG13186 - - - - 41587 1993.93 32.08 22.29 -0.525277525195168 Down 0.595628054418175 grsm granny smith, isoform F K09611|1|0.0|1116|dya:Dyak_GE24479|probable aminopeptidase NPEPL1 [EC:3.4.11.-] - - - 31577 2134.00 19.745 21.455 0.119826533288037 Up 0.238772949412231 CG3847 CG3847 K09228|1|4e-22|106|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein - - - 36722 1548.00 16.16 15.085 -0.0993125016050924 Down 0.19208162726192 eIF2B-gamma eIF2B-gamma K03241|1|0.0|911|dme:Dmel_CG8190|translation initiation factor eIF-2B gamma subunit GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0030695//GTPase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006412//translation 36936 453.00 78.985 53.725 -0.555985120189287 Down 0.643243957205125 Gbp Growth-blocking peptide - - - - 33334 616.00 0.07 0.095 0.440572591385981 Up 0.0547483819838859 halo halo - - - GO:0050789//regulation of biological process;GO:0016310//phosphorylation;GO:0010970//microtubule-based transport 19835855 495.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 5740402 1777.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 CG34345 CG34345 K00472|1|0.0|1026|dme:Dmel_CG34345|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0019471 40239 1853.00 5.315 5.775 0.119751254772316 Up 0.148064984810461 Rbbp5 Rbbp5 K12857|1|3e-12|73.6|tad:TRIADDRAFT_37206|Prp8 binding protein;K04508|4|8e-12|72.4|mdo:100031835|transducin (beta)-like 1 - - - 38022 1117.00 14.085 13.245 -0.0887117200053085 Down 0.170122837141725 CG7049 CG7049 K13444|1|0.0|698|dme:Dmel_CG7049|sulfatase modifying factor 1 - - - 35792 1767.49 0.28 0.88 1.65207669657969 Up 0.292893937392683 CG8708 CG8708, isoform D K00731|1|1e-171|602|dvi:Dvir_GJ14139|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part GO:0008378//galactosyltransferase activity GO:0006464//cellular protein modification process 34777 1370.45 1.585 2.165 0.449884184587318 Up 0.228668603883239 CG9014 CG9014, isoform B K11981|1|0.0|635|dme:Dmel_CG9014|E3 ubiquitin-protein ligase NRDP1 [EC:6.3.2.19] GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation 33121 392.95 20.025 55.905 1.48117507715393 Up 0.746796988508784 CG1678 CG1678, isoform B - - - - 42574 463.00 0.47 0.205 -1.19703684705955 Down 0.176726984546295 Cby chibby, isoform D - - - GO:0007365//periodic partitioning;GO:0016055//Wnt receptor signaling pathway 41708 636.97 23 25.34 0.139782663309072 Up 0.279025227843085 CG9922 CG9922, isoform B - - - - 38841 1573.00 21.615 6.325 -1.77289545131423 Down 0.729163914938581 Cyp4d8 cytochrome P450-4d8 K00517|1|0.0|929|dme:Dmel_CG4321| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 37427 2261.83 13.645 12.13 -0.16979284415363 Down 0.270472856954167 MFS16 major facilitator superfamily transporter 16, isoform D K13783|1|0.0|1020|dse:Dsec_GM15825|MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2 - - - 36953 2025.14 14.735 13.64 -0.111403416099828 Down 0.201591599524501 l(2)k01209 lethal (2) k01209, isoform D K00876|1|0.0|1049|dsi:Dsim_GD11264|uridine kinase [EC:2.7.1.48] - - - 36814 456.00 11.57 27.7 1.25949711182906 Up 0.7062145027077 CG15704 CG15704 - - GO:0003824//catalytic activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process 35440 3279.82 10.645 11.615 0.125813204356514 Up 0.208228767666094 CG3651 CG3651, isoform D - - - - 14462377 428.00 1.105 0.96 -0.202940058670275 Down 0.093778893144895 14462773 1861.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 43309 1239.00 0.19 0.255 0.42449782852791 Up 0.0781931052701096 Gr98d gustatory receptor 98d K08471|1|0.0|790|dme:Dmel_CG31061|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33034 1282.00 20.5 20.1 -0.0284284083265173 Down 0.0926231673490952 Syx16 syntaxin 16 K08489|1|0.0|661|dme:Dmel_CG1467|syntaxin 16 GO:0031224//intrinsic to membrane;GO:0000323//lytic vacuole;GO:0012505//endomembrane system GO:0005515//protein binding GO:0001505//regulation of neurotransmitter levels;GO:0046907//intracellular transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport 5740176 2830.45 7.13 8.59 0.268756054694576 Up 0.311451591599525 CG34340 CG34340, isoform F K09330|1|3e-25|117|xtr:100124329|paired mesoderm homeobox protein 2 - - GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 42845 2968.37 27.01 27.64 0.0332639758792916 Up 0.100482102760534 Miro mitochondrial Rho, isoform F K07870|1|0.0|655|spu:586242|Ras homolog gene family, member T1 GO:0031306//intrinsic to mitochondrial outer membrane;GO:0031306//intrinsic to mitochondrial outer membrane;GO:0031306//intrinsic to mitochondrial outer membrane GO:0046872//metal ion binding;GO:0032561//guanyl ribonucleotide binding;GO:0003824//catalytic activity;GO:0046872//metal ion binding;GO:0032561//guanyl ribonucleotide binding;GO:0003824//catalytic activity;GO:0046872//metal ion binding;GO:0032561//guanyl ribonucleotide binding;GO:0003824//catalytic activity GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0035556//intracellular signal transduction;GO:0051640//organelle localization;GO:0007267//cell-cell signaling;GO:0000226//microtubule cytoskeleton organization;GO:0010970//microtubule-based transport;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0035556//intracellular signal transduction;GO:0051640//organelle localization;GO:0007267//cell-cell signaling;GO:0000226//microtubule cytoskeleton organization;GO:0010970//microtubule-based transport;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0035556//intracellular signal transduction;GO:0051640//organelle localization;GO:0007267//cell-cell signaling;GO:0000226//microtubule cytoskeleton organization;GO:0010970//microtubule-based transport 40661 2334.73 37.965 44.93 0.243009053691598 Up 0.430887597411174 CG31550 CG31550, isoform D K13096|1|0.0|1136|dsi:Dsim_GD19790|splicing factor 4 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding - 37610 3761.00 0.065 0.225 1.79141337818858 Up 0.144102496367719 CG30268 CG30268 - - - - 45682 1195.73 104.09 98.23 -0.0835958703515028 Down 0.214403645489367 eIF-3p40 eukaryotic initiation factor 3 p40 subunit, isoform B K03247|1|0.0|651|dme:Dmel_CG9124|translation initiation factor eIF-3 subunit 3 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0006412//translation 38282 5265.00 0.48 0.425 -0.175571564583454 Down 0.0649848104609695 osm-1 outer segment 2 - GO:0044464//cell part GO:0005488//binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007389//pattern specification process 43088 1044.11 2.815 5.795 1.04167373892624 Up 0.531765949015982 ymp yellow-emperor, isoform D K14015|1|2e-65|248|dse:Dsec_GM10234|nuclear protein localization protein 4 homolog GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - GO:0000377;GO:0000377 14462346 2488.00 0.625 0.07 -3.15842936260448 Down 0.310989301281205 34701 8461.45 44.095 40.6 -0.119135348232605 Down 0.271826707172104 CG9932 CG9932, isoform E K09222|1|5e-13|78.6|dre:564772|RE1-silencing transcription factor;K09228|4|1e-12|77.4|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 38246 2363.97 87.15 79.3 -0.136179798421707 Down 0.322018227446837 CG12025 CG12025, isoform C - - - - 43437 1373.85 285.295 289.24 0.0198126184999006 Up 0.0925901466120724 CG11876 CG11876, isoform D K00162|1|7e-119|426|dan:Dana_GF23287|pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0004738//pyruvate dehydrogenase activity;GO:0004738//pyruvate dehydrogenase activity GO:0032787//monocarboxylic acid metabolic process;GO:0000226//microtubule cytoskeleton organization;GO:0032787//monocarboxylic acid metabolic process;GO:0000226//microtubule cytoskeleton organization;GO:0032787//monocarboxylic acid metabolic process;GO:0000226//microtubule cytoskeleton organization;GO:0032787//monocarboxylic acid metabolic process;GO:0000226//microtubule cytoskeleton organization 39678 1034.00 0.46 0.215 -1.09729720135491 Down 0.167316074494783 yellow-k yellow-k - - - - 39971 5104.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG6052 CG6052 K05643|1|0.0|892|hmg:100197302|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 33841 1662.00 0.87 0.365 -1.25311893696871 Down 0.254920089816405 H2.0 homeodomain protein 2.0 K09339|1|9e-158|556|dme:Dmel_CG11607|homeobox protein HLX1 GO:0043231//intracellular membrane-bounded organelle GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0045622//regulation of T-helper cell differentiation;GO:0006350;GO:0048522//positive regulation of cellular process 41144 3028.73 34.085 29.145 -0.225888581398759 Down 0.404801215163122 by blistery, isoform D K00665|1|1e-84|315|dpe:Dper_GL12292|fatty acid synthase, animal type [EC:2.3.1.85];K08890|2|8e-06|53.1|tgu:100223292|B lymphoid tyrosine kinase [EC:2.7.10.2] GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0007472//wing disc morphogenesis;GO:0007010//cytoskeleton organization;GO:0007472//wing disc morphogenesis;GO:0007010//cytoskeleton organization;GO:0007472//wing disc morphogenesis;GO:0007010//cytoskeleton organization 19835383 1787.50 4.655 5.29 0.184486554555232 Up 0.192940166424515 - phosphatidylinositol glycan anchor biosynthesis, class V ortholog, isoform C - - - - 117353 2519.60 57.09 49.48 -0.206392562018808 Down 0.407112666754722 Cct1 CTP:phosphocholine cytidylyltransferase 1, isoform F K00968|1|0.0|851|dme:Dmel_CG1049|choline-phosphate cytidylyltransferase [EC:2.7.7.15] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0070567;GO:0070567;GO:0070567;GO:0070567 GO:0016192//vesicle-mediated transport;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0046470//phosphatidylcholine metabolic process;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0046470//phosphatidylcholine metabolic process;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0046470//phosphatidylcholine metabolic process;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0046470//phosphatidylcholine metabolic process;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0001736//establishment of planar polarity 38167 3219.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 SA-2 Stromalin-2 K06671|1|0.0|1747|dme:Dmel_CG13916|cohesin complex subunit SA-1/2 GO:0044427//chromosomal part - GO:0009987//cellular process 43421 625.00 2.175 0.605 -1.8460083534615 Down 0.458459912825254 CG14518 CG14518 K12602|1|2e-33|142|dpo:Dpse_GA17766|WD repeat-containing protein 61;K09255|2|2e-11|68.6|dpe:Dper_GL18753|Rel/ankyrin family, other - GO:0019842//vitamin binding;GO:0016491//oxidoreductase activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process 42984 2853.00 20.725 21.925 0.0812047409489824 Up 0.178543125082552 CG11771 CG11771 K01414|1|0.0|1431|dme:Dmel_CG11771|oligopeptidase A [EC:3.4.24.70] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38165 2273.00 0.81 0.97 0.260062839302503 Up 0.10484084004755 CG9173 CG9173 - - - - 32490 2159.00 4.445 4.55 0.0336831262562886 Up 0.0618808611808216 CG9213 CG9213, isoform B - - - - 10178956 3022.00 0.04 0.01 -2 Down 0.0694426099590543 19835334 904.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 31613 856.44 554.42 625.44 0.173892187927814 Up 0.388356888125743 RpL17 ribosomal protein L17, isoform E K02880|1|6e-95|347|dse:Dsec_GM12554|large subunit ribosomal protein L17e - - - 33410 764.00 0.725 0.76 0.0680184234286512 Up 0.0525359926033549 CG4271 CG4271 K01362|1|9e-25|113|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|7e-24|110|dpo:Dpse_GA15051|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19836100 583.00 0.295 0.325 0.139724763666613 Up 0.0546823405098402 41608 1337.00 0.06 0.105 0.807354922057604 Up 0.07657508915599 CG11670 CG11670 K01312|1|1e-33|144|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4];K08664|2|4e-25|115|hsa:5652|protease, serine, 8 (prostasin) [EC:3.4.21.-];K01324|3|5e-25|115|ssc:397144|plasma kallikrein [EC:3.4.21.34] - - - 14462651 658.00 0.245 0.01 -4.61470984411521 Down 0.239499405626734 42093 4358.59 28.515 30.2 0.0828275168427333 Up 0.190562673358869 Sur-8 Sur-8, isoform F K01768|1|9e-47|189|dpo:Dpse_GA10197|adenylate cyclase [EC:4.6.1.1] - - - 37710 1067.43 5.36 4.35 -0.301217599721682 Down 0.275128780874389 CG9815 CG9815, isoform D - - - - 40812 1409.00 8.12 2.125 -1.93401688616011 Down 0.665070664377229 CG1315 CG1315, isoform B K01940|1|0.0|845|dme:Dmel_CG1315|argininosuccinate synthase [EC:6.3.4.5] GO:0044424//intracellular part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559 GO:0006525//arginine metabolic process;GO:0019627//urea metabolic process 37450 2753.00 6.655 5.96 -0.15912633544973 Down 0.194128912957337 CG10496 TATA box-binding protein-associated factor RNA polymerase I subunit C-like - - - - 39263 668.00 64.835 64.525 -0.00691459985785156 Down 0.0641923127724211 CG7607 CG7607 - - - - 42852 2231.00 154.66 156.465 0.0167398554601077 Up 0.0908070268128385 Hsp68 heat shock protein 68 K03283|1|0.0|1162|dme:Dmel_CG5436|heat shock 70kDa protein 1/8 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0032559 GO:0010259//multicellular organismal aging;GO:0006950//response to stress;GO:0044267//cellular protein metabolic process 46068 3452.58 221.155 200.775 -0.139478220188362 Down 0.335622771100251 Acsl Acyl-CoA synthetase long-chain, isoform J K01897|1|0.0|1383|dme:Dmel_CG8732|long-chain acyl-CoA synthetase [EC:6.2.1.3] - GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 40430 1049.00 45.02 39.65 -0.183245190862815 Down 0.361775194822348 CG7407 CG7407 - - - - 31176 923.00 10.835 10.86 0.0033249497106877 Up 0.0416061286487914 CG4045 CG4045 K03439|1|4e-150|530|dme:Dmel_CG4045|tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] - - - 33412 475.00 0.28 1.075 1.94083792753186 Up 0.344010038304055 robl22E robl22E, isoform B K10419|1|2e-25|114|cqu:CpipJ_CPIJ002048|dynein light chain roadblock-type GO:0005875//microtubule associated complex GO:0016887//ATPase activity GO:0048812//neuron projection morphogenesis;GO:0007017//microtubule-based process;GO:0007420//brain development 19836118 249.00 0.96 0.43 -1.15869774601906 Down 0.259807158895787 35821 1386.11 0.375 0.125 -1.58496250072116 Down 0.182406551314225 Cyp4ad1 Cyp4ad1, isoform B K00517|1|0.0|1006|dme:Dmel_CG2110| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 42037 3935.00 0.115 0.07 -0.716207033999408 Down 0.0690133403777572 abd-A abdominal A, isoform D K09311|1|2e-117|424|dme:Dmel_CG10325|Antp family, other;K09307|3|5e-24|114|xla:373643|homeobox protein HoxA/B7 - GO:0030528//transcription regulator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0035051//cardiocyte differentiation;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0008354//germ cell migration;GO:0012501//programmed cell death;GO:0001742//oenocyte differentiation;GO:0014706//striated muscle tissue development;GO:0045137//development of primary sexual characteristics;GO:0001708//cell fate specification;GO:0014016//neuroblast differentiation;GO:0010551;GO:0001709//cell fate determination;GO:0048565//digestive tract development;GO:0007445;GO:0048634 35398 4399.64 13.485 12.45 -0.11520977928016 Down 0.205917316074495 Hr39 hormone receptor-like in 39, isoform D K08705|1|0.0|1424|dme:Dmel_CG8676|nuclear receptor subfamily 5 group A member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding GO:0035071//salivary gland cell autophagic cell death;GO:0010468//regulation of gene expression;GO:0009887//organ morphogenesis;GO:0007143//female meiosis;GO:0006351//transcription, DNA-dependent;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0010468//regulation of gene expression;GO:0009887//organ morphogenesis;GO:0007143//female meiosis;GO:0006351//transcription, DNA-dependent;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0010468//regulation of gene expression;GO:0009887//organ morphogenesis;GO:0007143//female meiosis;GO:0006351//transcription, DNA-dependent;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0010468//regulation of gene expression;GO:0009887//organ morphogenesis;GO:0007143//female meiosis;GO:0006351//transcription, DNA-dependent;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 32068 779.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 sisA sisterless A - GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0007494//midgut development;GO:0009888//tissue development;GO:0003006//developmental process involved in reproduction 43209 810.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 TwdlS TweedleS - - - - 39322 1650.79 15.755 11.445 -0.461092291461853 Down 0.50683529256373 Bmcp bmcp, isoform B K03454|1|5e-158|557|dpo:Dpse_GA20254|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0008152//metabolic process;GO:0006810//transport;GO:0008152//metabolic process 40620 7644.83 24.1 27.46 0.188298479029777 Up 0.348170651168934 cno canoe, isoform I K05702|1|0.0|2742|dan:Dana_GF16070|afadin GO:0005913//cell-cell adherens junction;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0005913//cell-cell adherens junction;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0005913//cell-cell adherens junction;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0001654//eye development;GO:0007264//small GTPase mediated signal transduction;GO:0007392;GO:0043408//regulation of MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0007389//pattern specification process;GO:0001654//eye development;GO:0007264//small GTPase mediated signal transduction;GO:0007392;GO:0043408//regulation of MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0007389//pattern specification process;GO:0001654//eye development;GO:0007264//small GTPase mediated signal transduction;GO:0007392;GO:0043408//regulation of MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0007389//pattern specification process 36473 991.24 75.415 81.595 0.113629245810473 Up 0.268953903051116 CG42319 CG42319, isoform F K05631|1|7e-06|53.1|dre:474349|atrophin-1 interacting protein 3 (BAI1-associated protein 1) - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 43326 976.00 4.785 4.03 -0.247739085958058 Down 0.227711002509576 CG12883 CG12883 - - - - 43935 1876.00 10.33 12.055 0.222791396737467 Up 0.309833575485405 NtR NtR, isoform B K05312|1|2e-09|64.7|cin:100183680|nicotinic acetylcholine receptor, invertebrate;K04808|3|3e-07|57.4|rno:81721|nicotinic acetylcholine receptor alpha-6 GO:0031224//intrinsic to membrane GO:0015276//ligand-gated ion channel activity GO:0006810//transport 31987 5456.56 21.52 17.405 -0.306176263832941 Down 0.447695152555805 spri sprint, isoform R - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007297//ovarian follicle cell migration;GO:0016192//vesicle-mediated transport;GO:0023060;GO:0007297//ovarian follicle cell migration;GO:0016192//vesicle-mediated transport;GO:0023060;GO:0007297//ovarian follicle cell migration;GO:0016192//vesicle-mediated transport;GO:0023060;GO:0007297//ovarian follicle cell migration;GO:0016192//vesicle-mediated transport;GO:0023060 37319 668.46 65.49 63.495 -0.0446316416723709 Down 0.131620657773081 Cpr57A cuticular protein 57A, isoform B - - - - 33222 6681.10 5.12 6.085 0.249113452713728 Up 0.252905824858011 CG4297 CG4297, isoform D - - - - 38381 1363.70 4.945 7.63 0.62571253607542 Up 0.473880597014925 CG14962 ASCIZ homolog, isoform B K09228|1|4e-07|57.0|mmu:24132|KRAB domain-containing zinc finger protein;K00383|4|7e-06|52.8|spu:589396|glutathione reductase (NADPH) [EC:1.8.1.7] GO:0044464//cell part GO:0046914//transition metal ion binding - 38662 1633.00 0.03 0.03 0 - 0.0382380134724607 CG5592 CG5592 K08204|1|8e-58|224|mdo:100011322|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 7;K08209|2|1e-56|220|mmu:102570|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13 GO:0031224//intrinsic to membrane - GO:0006810//transport 44010 1843.00 223.53 243.86 0.125584665623327 Up 0.319112402588826 Pgm phosphoglucose mutase K01835|1|0.0|1122|dme:Dmel_CG5165|phosphoglucomutase [EC:5.4.2.2] - GO:0046872//metal ion binding;GO:0016868//intramolecular transferase activity, phosphotransferases GO:0040011//locomotion;GO:0005977//glycogen metabolic process 39630 3903.76 13.045 16.56 0.344205728681873 Up 0.446737551182142 Sytbeta synaptotagmin beta, isoform D K01104|1|1e-45|185|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|2|2e-20|102|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10];K02677|3|7e-11|70.5|nve:NEMVE_v1g93932|classical protein kinase C [EC:2.7.11.13] GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle - GO:0001505//regulation of neurotransmitter levels;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006887//exocytosis 19835096 534.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 39964 981.46 71.785 56.235 -0.35221408752821 Down 0.547913089420156 CG6259 CG6259, isoform B K12198|1|3e-105|381|dme:Dmel_CG6259|charged multivesicular body protein 5 - - GO:0006810//transport 40456 4866.00 25.28 25.885 0.0341198546838242 Up 0.099524501386871 Rich RIC1 homolog - GO:0044464//cell part GO:0008047//enzyme activator activity GO:0009966//regulation of signal transduction 19836195 601.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 38413 870.61 180.65 184.645 0.0315569415783675 Up 0.114383833047154 PHGPx PHGPx, isoform D K00432|1|4e-96|350|dme:Dmel_CG12013|glutathione peroxidase [EC:1.11.1.9] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004601//peroxidase activity;GO:0004601//peroxidase activity;GO:0004601//peroxidase activity GO:0033194//response to hydroperoxide;GO:0008152//metabolic process;GO:0033194//response to hydroperoxide;GO:0008152//metabolic process;GO:0033194//response to hydroperoxide;GO:0008152//metabolic process 42593 2012.00 7.33 7.82 0.0933554091735404 Up 0.139050323603223 CG6015 CG6015 K12816|1|0.0|1167|dme:Dmel_CG6015|pre-mRNA-processing factor 17 GO:0005681//spliceosomal complex GO:0004468//lysine N-acetyltransferase activity GO:0000377 8674114 3113.00 175.315 209.795 0.259030856112125 Up 0.489565447100779 inaF-B inaF-B - GO:0031253//cell projection membrane GO:0005488//binding;GO:0016247//channel regulator activity GO:0009314//response to radiation;GO:0016057//regulation of membrane potential in photoreceptor cell 39612 2644.00 14.58 14.01 -0.057533763896119 Down 0.128945978074231 CG13472 tudor domain containing 3 ortholog K10990|1|8e-10|66.2|oaa:100073619|protein RMI1 homolog GO:0044424//intracellular part - - 43628 1782.00 0.955 0.59 -0.694785778673907 Down 0.189968300092458 PH4alphaNE2 prolyl-4-hydroxylase-alpha NE2 K00472|1|0.0|994|dme:Dmel_CG9720|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 19835672 350.00 0.14 0.305 1.12338241550528 Up 0.140668339717342 33350 2152.67 42.445 39.215 -0.114189014606338 Down 0.254920089816405 CG18317 Rim2 ortholog, isoform D K13354|1|3e-33|143|nvi:100116581|solute carrier family 25 member 17;K03454|2|8e-24|112|xla:100137670|mitochondrial carrier protein, MC family GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005215//transporter activity GO:0046907//intracellular transport 34630 1218.76 75.425 92.42 0.29316229813247 Up 0.506571126667547 Pex19 peroxin 19, isoform C K13337|1|1e-132|473|dme:Dmel_CG5325|peroxin-19 GO:0042579//microbody;GO:0042579//microbody - GO:0048731;GO:0048731 35002 2265.00 0.78 0.22 -1.82597060022495 Down 0.287148329150707 ChLD3 ChLD3 K04550|1|2e-07|57.8|spu:582052|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor);K06233|2|9e-07|55.8|dre:568184|low density lipoprotein-related protein 2;K12473|3|2e-06|55.1|ecb:100057389|low-density lipoprotein receptor - GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity GO:0006022 33593 571.00 10.415 3.06 -1.76705928134799 Down 0.67887333245278 CG3604 CG3604, isoform B K03909|1|6e-12|70.5|mdo:100028266|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 38031 1337.00 6.635 7.46 0.169079164885045 Up 0.214271562541276 CG13876 CG13876 - - GO:0003676//nucleic acid binding;GO:0048037//cofactor binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0034061 GO:0006260//DNA replication 14462781 509.00 0.405 0.01 -5.33985000288463 Down 0.322183331131951 36345 852.00 9.105 2.315 -1.9756468237166 Down 0.678047814027209 Cpr49Ab cuticular protein 49Ab - - GO:0005198//structural molecule activity - 36981 2564.99 95.02 86.97 -0.127713372628291 Down 0.307357020208691 eIF3-S9 eIF3-S9, isoform B K03253|1|0.0|1332|dme:Dmel_CG4878|translation initiation factor eIF-3 subunit 9 - - - 37572 1955.00 1.15 1.275 0.148863385914483 Up 0.0855237088891824 CG6018 CG6018 K01044|1|0.0|742|dme:Dmel_CG1031|carboxylesterase [EC:3.1.1.1];K03927|2|0.0|734|dse:Dsec_GM10467|carboxylesterase type B [EC:3.1.1.1] - GO:0004091//carboxylesterase activity - 36772 4114.74 29.425 32.5 0.143397302877373 Up 0.293950600977414 CG8405 CG8405, isoform B - - - - 19834877 1027.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 12798491 558.90 0.08 0.25 1.64385618977472 Up 0.147833839651301 38773 540.00 0.085 0.21 1.30485458152842 Up 0.119601109496764 Cpr65Ea cuticular protein 65Ea - - GO:0005198//structural molecule activity - 12798056 1043.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 CG43060 CG43060, isoform B - - - - 19835325 382.00 0.115 0.255 1.14886338591448 Up 0.127228899749042 43592 1158.00 2.385 3.195 0.421826664941483 Up 0.266774534407608 CG15531 CG15531 K00507|1|3e-176|617|dse:Dsec_GM12171|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] GO:0031224//intrinsic to membrane GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0006631//fatty acid metabolic process 19834953 1188.00 0.135 0.09 -0.584962500721156 Down 0.0687491744815744 3885569 459.81 7.125 2.55 -1.48239276708061 Down 0.615176330735702 CG34026 CG34026, isoform B - - - - 34564 1191.00 43.225 33.325 -0.375261088553308 Down 0.545733720776648 Ppt2 Palmitoyl-protein thioesterase 2 K01074|1|7e-167|586|dme:Dmel_CG4851|palmitoyl-protein thioesterase [EC:3.1.2.22] - GO:0016790//thiolester hydrolase activity GO:0043412//macromolecule modification 34234 799.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 CG12439 CG12439, isoform B - - - - 37742 1206.00 56.545 44.445 -0.347378332311962 Down 0.538337075683529 St1 sulfotransferase 1 K01018|1|5e-50|198|dme:Dmel_CG5431|tyrosine-ester sulfotransferase [EC:2.8.2.9];K01025|2|6e-38|158|tgu:100190592| [EC:2.8.2.-];K01014|4|9e-37|154|dme:Dmel_CG16733|aryl sulfotransferase [EC:2.8.2.1];K01016|5|4e-36|152|dpo:Dpse_GA14114|estrone sulfotransferase [EC:2.8.2.4] - GO:0016782//transferase activity, transferring sulfur-containing groups - 38201 1534.00 8.185 6.45 -0.343683256163537 Down 0.358175934486858 CG17249 CG17249 K13105|1|0.0|672|dme:Dmel_CG17249|proline-rich protein PRCC - - - 38193 2482.20 33.96 35.95 0.0821553117736216 Up 0.195713908334434 ABCB7 ABCB7, isoform B K05663|1|0.0|1126|dme:Dmel_CG7955|mitochondrial ABC transporter ATM;K05662|2|0.0|689|oaa:100075231|ATP-binding cassette, subfamily B (MDR/TAP), member 7 GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0019866//organelle inner membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0051184;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0051184;GO:0032559 GO:0051181//cofactor transport;GO:0031163;GO:0051181//cofactor transport;GO:0031163 41525 1194.00 28.95 37.835 0.386158096915655 Up 0.543653414344208 Scgbeta sarcoglycan beta K12566|1|0.0|657|dme:Dmel_CG5657|beta-sarcoglycan - - - 42326 1188.00 1.165 2.53 1.11880743004003 Up 0.403513406419231 CG6255 CG6255 K01899|1|4e-166|583|dme:Dmel_CG6255|succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0009060//aerobic respiration 31265 2002.00 6.855 7.25 0.0808243291230708 Up 0.122308809932638 dwg deformed wings K09228|1|2e-62|240|mmu:212281|KRAB domain-containing zinc finger protein - - - 35250 3555.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 Tep5 Thioester-containing protein 5 K06530|1|2e-87|324|dme:Dmel_CG7052|CD109 antigen GO:0044421//extracellular region part GO:0061135;GO:0005488//binding - 36764 1889.63 15.69 11.215 -0.484415731881825 Down 0.514859331660283 CG8389 CG8389, isoform B K11810|1|2e-19|97.4|bfo:BRAFLDRAFT_210112|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 12;K08190|2|5e-13|76.3|mdo:100014050|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14;K08184|3|7e-13|75.9|mcc:716540|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 7;K08183|4|9e-13|75.5|cfa:490900|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 6 - - GO:0006810//transport;GO:0006810//transport 14462815 393.00 0.22 0.265 0.268488835925902 Up 0.0687821952185973 36637 788.00 30.145 38.94 0.369334154682528 Up 0.534341566503764 AttB Attacin-B, isoform B - GO:0044421//extracellular region part;GO:0044421//extracellular region part - GO:0042742//defense response to bacterium;GO:0042742//defense response to bacterium 37086 568.00 0.715 0.01 -6.15987133677839 Down 0.4293356227711 CG14499 CG14499 - - - - 38016 944.42 0.9 1.35 0.584962500721156 Up 0.208393871351209 CG13405 CG13405, isoform B - - - - 10178795 593.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 CG42762 CG42762 - - - - 33705 1258.96 13.62 13.795 0.0184187533412019 Up 0.0677585523708889 jet jetlag, isoform B K10281|1|8e-176|616|dsi:Dsim_GD22679|F-box and leucine-rich repeat protein 15 - - GO:0009648//photoperiodism;GO:0007622//rhythmic behavior;GO:0009648//photoperiodism;GO:0007622//rhythmic behavior 37109 839.00 0.82 1.845 1.16992500144231 Up 0.357911768590675 GstE4 glutathione S transferase E4 K00799|1|2e-125|447|dme:Dmel_CG17525|glutathione S-transferase [EC:2.5.1.18] - - - 33976 1973.00 1.98 1.74 -0.186413124230881 Down 0.118544445912033 CG3430 CG3430 - - - - 41671 3927.19 18.59 22.79 0.293874154345815 Up 0.437425703341699 Task6 TWIK-related acid-sensitive K[+] channel 6, isoform F K05323|1|0.0|809|dme:Dmel_CG9637|potassium channel subfamily K, invertebrate - - - 39377 2311.90 76.46 76.86 0.00752777622815376 Up 0.0658103288865407 yps ypsilon schachtel, isoform B K09276|1|5e-30|132|spu:580680|Y-box-binding protein 1;K06099|2|3e-29|130|rno:83807|cold shock domain protein A GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 7354436 851.00 0.43 0.845 0.974614681580086 Up 0.219786025624092 CG42395 CG42395 - - - - 12797885 2763.00 0.065 0.11 0.758991900496205 Up 0.0694426099590543 3772098 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 33822 724.00 8.95 10.895 0.283706608964288 Up 0.352001056663585 CG9016 CG9016, isoform B - - - - 36682 1780.00 14.59 12.605 -0.210983765059351 Down 0.31881521595562 CG8090 golgi pH regulator - - - - 43545 907.00 2.87 0.975 -1.55757661292608 Down 0.482763175274072 Jon99Ci jonah 99Ci K01362|1|2e-162|571|dme:Dmel_CG31039| [EC:3.4.21.-];K01310|2|2e-78|291|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1] - GO:0004175//endopeptidase activity GO:0032501//multicellular organismal process;GO:0019538//protein metabolic process 19835147 413.00 1.73 0.12 -3.84966572691557 Down 0.522255976753401 19834915 1225.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 12798347 553.00 1.685 1.82 0.111189859016838 Up 0.0833443402456743 CG43111 CG43111 - - - - 33989 2529.30 65.185 72.395 0.151350042329964 Up 0.333839651301017 CG11266 CG11266, isoform L K13091|1|0.0|673|dme:Dmel_CG11266|RNA-binding protein 39 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 41571 6420.00 1.19 1.745 0.552265462901709 Up 0.232201822744684 mus308 mutagen-sensitive 308 K02349|1|0.0|3920|dme:Dmel_CG6019|DNA polymerase theta subunit [EC:2.7.7.7] - - - 48805 1698.00 22.09 23.105 0.0648116708112595 Up 0.150475498613129 Catsup catecholamines up - GO:0016020//membrane - GO:0006584//catecholamine metabolic process 35346 659.00 3.435 2.255 -0.607182665562719 Down 0.341533483027341 CheB38c chemosensory protein B 38c - GO:0044421//extracellular region part - GO:0009593//detection of chemical stimulus 37161 5609.71 23.6 33.685 0.513319439738077 Up 0.592392022189935 Hs3st-A heparan sulfate 3-O sulfotransferase-A, isoform B K08104|1|0.0|845|dme:Dmel_CG33147|[heparan sulfate]-glucosamine 3-sulfotransferase 5 [EC:2.8.2.23] - - - 39993 698.00 0.29 0.22 -0.398549376490275 Down 0.0821555937128517 CG16775 CG16775 - - - - 318875 632.00 3.335 3.555 0.0921627984348302 Up 0.0958591995773346 CG31659 CG31659, isoform B K05128|1|1e-05|50.1|ame:410190|RYK receptor-like tyrosine kinase [EC:2.7.10.1] - GO:0005488//binding;GO:0005488//binding - 43912 2523.41 28.555 35.16 0.300191685887057 Up 0.477314753665302 SF1 splicing factor 1, isoform C K13095|1|0.0|965|dme:Dmel_CG5836|splicing factor 1 GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0000377;GO:0002118//aggressive behavior 19835159 425.00 0.73 0.375 -0.961005868384136 Down 0.204860652489764 41370 7465.00 7.905 6.75 -0.227877960420177 Down 0.269152027473253 CG5270 CG5270 - - GO:0046914//transition metal ion binding - 36548 1081.00 0.22 0.21 -0.0671141958585369 Down 0.042365605600317 St4 sulfotransferase 4, isoform B K01025|1|2e-38|159|bta:783020| [EC:2.8.2.-] - GO:0016782//transferase activity, transferring sulfur-containing groups - 32344 715.00 0.225 0.13 -0.791413378188582 Down 0.101637828556333 CG10993 CG10993 - - GO:0005488//binding - 42755 1959.00 1.035 2.005 0.953971468955595 Up 0.336151102892617 CG17083 CG17083 K12478|1|2e-07|58.2|cin:751565|early endosome antigen 1;K11498|2|1e-06|55.5|dse:Dsec_GM18973|centromeric protein E;K10421|3|1e-06|55.1|oaa:100075022|CAP-Gly domain-containing linker protein 1;K11499|4|7e-06|52.8|spu:592172|centromere protein F - - - 14462809 381.00 0.23 0.13 -0.823122237915921 Down 0.102397305507859 14462516 549.00 3.43 1.77 -0.954459216089815 Down 0.426726984546295 34279 1822.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 CG4382 CG4382 K03927|1|8e-83|308|dpe:Dper_GL18918|carboxylesterase type B [EC:3.1.1.1] - - - 35414 2703.13 1.745 1.5 -0.218264535713771 Down 0.124785365209351 nompB no mechanoreceptor potential B, isoform D - - - - 32622 4943.73 3.92 4.62 0.237039197300849 Up 0.216417910447761 CG9902 CG9902, isoform B - - - - 5740528 4401.99 20.815 27.56 0.404952329564073 Up 0.52872804120988 CG34354 CG34354, isoform F K13201|1|2e-62|241|dre:394107|nucleolysin TIAR - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 31967 1668.00 43.925 41.105 -0.0957283926560321 Down 0.23632941487254 Psf3 Psf3, isoform C K10734|1|2e-121|435|dme:Dmel_CG2222|GINS complex subunit 3 GO:0043231//intracellular membrane-bounded organelle GO:0003678//DNA helicase activity GO:0006259//DNA metabolic process 19835088 592.00 0.01 0.08 3 Up 0.110718531237617 32073 3177.84 17.7 20.495 0.211522629664419 Up 0.350416061286488 CG1597 CG1597, isoform C K01228|1|0.0|1635|dme:Dmel_CG1597|mannosyl-oligosaccharide glucosidase [EC:3.2.1.106] - GO:0015926//glucosidase activity GO:0005975//carbohydrate metabolic process 39829 1771.00 38.46 39.865 0.0517639064258189 Up 0.143640206049399 Aats-tyr Tyrosyl-tRNA synthetase K01866|1|0.0|954|dme:Dmel_CG4561|tyrosyl-tRNA synthetase [EC:6.1.1.1] GO:0044424//intracellular part GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0007033//vacuole organization;GO:0006418//tRNA aminoacylation for protein translation 41201 1695.00 8.53 7.36 -0.212839975261277 Down 0.264000792497689 CG12947 CG12947 - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 39982 1982.00 0.04 2.585 6.01402047031493 Up 0.672533350944393 Ir75a ionotropic receptor 75a - GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 318744 1736.00 0.16 0.315 0.977279923499916 Up 0.132148989565447 CG31454 CG31454 K02354|1|6e-16|85.5|spu:583340|frizzled 4 - - - 44005 689.61 16.115 12.65 -0.349266803477873 Down 0.449214106458856 NHP2 NHP2, isoform B K11129|1|1e-75|282|dse:Dsec_GM24527|H/ACA ribonucleoprotein complex subunit 2 GO:0030529//ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0030556//rRNA modification guide activity GO:0000154//rRNA modification 5740630 486.00 1.115 0.575 -0.95540984897593 Down 0.253203011491216 CG34204 CG34204, isoform B - - - - 50274 358.00 0.01 0.14 3.8073549220576 Up 0.163848897107383 CG13053 CG13053, isoform B - - - - 34773 1684.00 3.585 5.55 0.630514652535563 Up 0.424976885484084 CG9254 CG9254 K08193|1|0.0|980|dme:Dmel_CG9254|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0006810//transport;GO:0023060 326222 1448.00 0.3 0.24 -0.321928094887363 Down 0.0761127988376701 CG32564 CG32564 - - - - 38645 1692.74 66.005 56.09 -0.234831732390492 Down 0.436435081231013 CG10576 CG10576, isoform D K05084|1|1e-104|380|mcc:711407|receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1];K01265|2|7e-24|112|xla:443662|methionyl aminopeptidase [EC:3.4.11.18] - GO:0003824//catalytic activity;GO:0003824//catalytic activity - 41701 1402.00 200.015 260.98 0.383831053144441 Up 0.589122969224673 Ipp inositol polyphosphate 1-phosphatase K01107|1|0.0|739|dme:Dmel_CG3028|inositol polyphosphate 1-phosphatase [EC:3.1.3.57] - - - 32997 713.00 0.01 0.155 3.95419631038688 Up 0.171410645885616 skpE skpE K03094|1|2e-92|337|dme:Dmel_CG11942|S-phase kinase-associated protein 1 GO:0005815//microtubule organizing center;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding GO:0051276//chromosome organization;GO:0019941//modification-dependent protein catabolic process;GO:0006261//DNA-dependent DNA replication;GO:0046605//regulation of centrosome cycle 246514 2877.00 3.22 3.655 0.18281071783782 Up 0.160249636771893 CG30203 CG30203 K04598|1|1e-07|59.3|mdo:100015832|brain-specific angiogenesis inhibitor 3 - GO:0004866//endopeptidase inhibitor activity - 7354402 1725.00 0.045 0.085 0.917537839808027 Up 0.0698718795403513 Ir60d ionotropic receptor 60d - - - - 14462400 622.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 33409 4352.09 24.14 24.21 0.00417740324391492 Up 0.0447430986659622 gho Sec24CD ortholog, isoform C K14007|1|0.0|1561|dme:Dmel_CG10882|protein transport protein SEC24 GO:0012507//ER to Golgi transport vesicle membrane GO:0046914//transition metal ion binding GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 317866 1785.00 1.25 2.51 1.00575926928868 Up 0.386903975696738 CG32119 CG32119 - - - - 41307 1369.00 21.295 9.365 -1.18516383030729 Down 0.685543521331396 CG14694 CG14694 - GO:0044464//cell part GO:0015291//secondary active transmembrane transporter activity;GO:0016597//amino acid binding GO:0051234//establishment of localization 5740702 898.00 0.305 0.15 -1.02384674195437 Down 0.135748249900938 CG34433 CG34433, isoform B - - - - 37336 631.42 86.3 97.055 0.169441979030765 Up 0.370888918240655 maf-S maf-S, isoform B K09037|1|6e-70|263|dan:Dana_GF12187|transcription factor MAFF/G/K - - - 3885656 581.00 1.155 0.42 -1.4594316186373 Down 0.319079381851803 CG34045 CG34045 - - - - 39001 522.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 Cp16 chorion protein 16 - - - - 43642 2038.00 0.285 0.115 -1.30932805810773 Down 0.143210936468102 Spn100A serpin 100A K13963|1|1e-25|118|bfo:BRAFLDRAFT_66649|serpin B - GO:0004866//endopeptidase inhibitor activity - 36594 1328.00 13.31 13.475 0.0177747017279762 Up 0.0666688680491349 CG8617 CG8617 - - - - 3772091 238.00 0.2 0.455 1.18586654531133 Up 0.176627922335227 36447 1067.31 46.785 30.51 -0.616763873516652 Down 0.640007924976886 GLaz glial lazarillo, isoform F K05128|1|1e-14|80.5|ame:410190|RYK receptor-like tyrosine kinase [EC:2.7.10.1] GO:0044421//extracellular region part - GO:0006950//response to stress;GO:0010259//multicellular organismal aging;GO:0051234//establishment of localization 19836163 1547.00 117.79 69.135 -0.768728890593865 Down 0.696671509708097 38068 1097.00 15.88 15.62 -0.0238164590009784 Down 0.0738343679830934 CG17180 CG17180, isoform B - - - - 260693 1164.00 0.1 1.105 3.46597446450407 Up 0.419891691982565 Or19b odorant receptor 19b K08471|1|0.0|707|dme:Dmel_CG32825|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 32418 3099.00 0.97 0.965 -0.00745580491904707 Down 0.0382380134724607 CG9514 CG9514 K00108|1|0.0|1393|dme:Dmel_CG9514|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 4379864 2859.00 0.355 0.455 0.358047520694014 Up 0.0935147272487122 lobo lost boys - - - - 261620 965.70 4.355 7.05 0.694950538687291 Up 0.481508387267204 CG31709 CG31709, isoform B - - - - 38516 5332.00 16.78 17.195 0.0352464000869674 Up 0.102595429929996 ago archipelago, isoform C K10260|1|0.0|2150|dme:Dmel_CG15010|F-box and WD-40 domain protein 7 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0040008//regulation of growth;GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0006935//chemotaxis;GO:0006261//DNA-dependent DNA replication;GO:0007067//mitosis;GO:0007346//regulation of mitotic cell cycle;GO:0040008//regulation of growth;GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0006935//chemotaxis;GO:0006261//DNA-dependent DNA replication;GO:0007067//mitosis;GO:0007346//regulation of mitotic cell cycle;GO:0040008//regulation of growth;GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0006935//chemotaxis;GO:0006261//DNA-dependent DNA replication;GO:0007067//mitosis;GO:0007346//regulation of mitotic cell cycle 38984 1565.35 22.365 23.37 0.0634149757782267 Up 0.149914146083741 CG5989 CG5989, isoform C - - - - 36868 1541.38 188.7 217.78 0.206777046150035 Up 0.43593977017567 CG5210 CG5210, isoform B K01183|1|5e-46|185|dpe:Dper_GL10147|chitinase [EC:3.2.1.14] - - - 14462563 500.00 0.18 0.28 0.637429920615292 Up 0.0984678378021397 19835988 1321.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 36358 1287.21 13.2 8.8 -0.584962500721156 Down 0.53440760797781 CG8525 CG8525, isoform D K01619|1|0.0|640|dme:Dmel_CG8525|deoxyribose-phosphate aldolase [EC:4.1.2.4] GO:0044424//intracellular part GO:0016832//aldehyde-lyase activity GO:0009166//nucleotide catabolic process 38675 1509.00 0.48 0.425 -0.175571564583454 Down 0.0649848104609695 alphaKap4 alpha Karyopherin-4 - - GO:0008565//protein transporter activity;GO:0005488//binding GO:0042993//positive regulation of transcription factor import into nucleus;GO:0009416//response to light stimulus 41377 3026.22 17.255 17.705 0.0371423699554001 Up 0.105204068154801 sals sarcomere length short, isoform H - - - - 34577 2393.85 188.815 142.67 -0.404291377705557 Down 0.595991282525426 CG31705 CG31705, isoform E K05741|1|7e-10|66.6|gga:374040|diaphanous 2;K05740|2|5e-07|57.0|ecb:100072186|diaphanous 1;K10385|3|3e-06|54.7|bta:505154|loricrin - - - 36143 973.00 28.455 27.42 -0.0534536083534058 Down 0.137267203803989 CG12343 CG12343 K12868|1|1e-115|416|dsi:Dsim_GD25952|pre-mRNA-splicing factor SYF2 GO:0005684//U2-type spliceosomal complex - GO:0000377 31486 1146.00 0.205 0.425 1.05183893151962 Up 0.159622242768459 CG42449 CG42449, isoform B - - - - 37098 1033.00 0.305 0.505 0.727474145188909 Up 0.140140007924977 CG14505 CG14505, isoform C - - - - 42797 1000.00 0.28 0.325 0.21501289097085 Up 0.0618148197067759 CG10301 CG10301 K10693|1|5e-06|51.6|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0044464//cell part - GO:0051234//establishment of localization 14462476 752.00 0.21 0.355 0.757429696725922 Up 0.118214238541804 CG44013 CG44013, isoform C - - - - 5740368 1155.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 CG34201 CG34201 - - - - 36838 822.00 9.45 9.34 -0.016891779398773 Down 0.0598335754854048 CG4398 CG4398 - - - - 5740442 5634.50 10.31 11.325 0.135466717565489 Up 0.218267071721041 CG34356 CG34356, isoform F K08876|1|4e-30|134|phu:Phum_PHUM420270|SCY1-like - GO:0003676//nucleic acid binding;GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006305 19835517 1105.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 19835428 543.00 2.475 1.625 -0.606988807051155 Down 0.291308942015586 38296 2699.44 2.995 2.96 -0.016958827159836 Down 0.0488046493197728 DmsR-2 myosuppressin receptor 2, isoform C K04233|1|3e-10|67.8|cel:ZK455.3|galanin receptor, invertebrate;K08428|2|5e-10|67.0|cfa:489988|G protein-coupled receptor 139 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0008528//G-protein coupled peptide receptor activity GO:0006937//regulation of muscle contraction;GO:0007166//cell surface receptor signaling pathway;GO:0006937//regulation of muscle contraction;GO:0007166//cell surface receptor signaling pathway 40580 2518.00 0.075 0.17 1.18057224564182 Up 0.108076872275789 rpk ripped pocket, isoform B K04832|1|3e-51|203|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|2|4e-17|90.5|spu:575477|amiloride-sensitive cation channel 2, neuronal;K04831|3|9e-14|79.3|dre:407667|amiloride-sensitive cation channel 4, pituitary GO:0031224//intrinsic to membrane GO:0005272//sodium channel activity GO:0030001//metal ion transport 34423 1134.00 2.78 2.97 0.0953780480772581 Up 0.0928543125082552 RfC3 replication factor C subunit 3 K10756|1|0.0|647|dsi:Dsim_GD23698|replication factor C subunit 3/5 GO:0015630//microtubule cytoskeleton;GO:0005657//replication fork GO:0003677//DNA binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0006259//DNA metabolic process 32279 1586.86 8.61 7.56 -0.187627003175771 Down 0.244650640602298 CG15743 CG15743, isoform C K12850|1|2e-94|346|dsi:Dsim_GD17111|pre-mRNA-splicing factor 38B;K01092|2|5e-57|222|dre:641570|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25];K01082|3|2e-35|150|tca:663948|3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] GO:0031224//intrinsic to membrane;GO:0044424//intracellular part GO:0004437//inositol or phosphatidylinositol phosphatase activity;GO:0043169//cation binding GO:0046488//phosphatidylinositol metabolic process;GO:0006793//phosphorus metabolic process;GO:0023060 36058 948.00 20.185 15.3 -0.399751933900496 Down 0.500957601373663 RpLP0-like ribosomal protein LP0-like K02941|1|1e-09|63.9|cin:100180640|large subunit ribosomal protein LP0 GO:0030529//ribonucleoprotein complex - GO:0022613//ribonucleoprotein complex biogenesis 38326 5070.26 28.62 32.62 0.188733109985217 Up 0.358374058908995 Pxn peroxidasin, isoform E K00431|1|4e-162|573|bfo:BRAFLDRAFT_67515|thyroid peroxidase [EC:1.11.1.8] - GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress 19835658 893.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 39634 544.00 0.08 0.84 3.39231742277876 Up 0.370294544974244 CG12310 CG12310 - - - - 41939 1647.68 37.39 34.56 -0.1135492536947 Down 0.25138687095496 CG4287 CG4287, isoform B - - - - 41943 6417.73 18.915 22.165 0.228752586115889 Up 0.375610883634923 Hel89B helicase 89B, isoform C K10841|1|9e-72|273|spu:575402|DNA excision repair protein ERCC-6 - - - 19835915 526.00 10.045 7.8 -0.364931534983681 Down 0.398824461761987 40448 3469.06 16.955 17.035 0.00679116307091583 Up 0.0526350548144235 CG7139 CG7139, isoform B K01567|1|9e-18|92.8|ptr:471175| [EC:3.-.-.-] - GO:0032559;GO:0032559 - 43756 2158.00 25.835 25.4 -0.0244983867653323 Down 0.0815281997094175 CG11576 CG11576 - - - - 37022 1905.00 0.1 0.115 0.20163386116965 Up 0.045898824461762 Ir54a ionotropic receptor 54a - - - - 34341 7274.25 5.525 7.165 0.374992239983352 Up 0.357713644168538 CG44153 CG44153, isoform B - GO:0044464//cell part GO:0004888//transmembrane signaling receptor activity - 33331 1565.00 0.57 1.21 1.08597322310985 Up 0.283053757759873 CG18131 CG18131, isoform H - - - - 34927 4066.89 15.89 11.665 -0.44593281736432 Down 0.501948223484348 Gli gliotactin, isoform F K07378|1|8e-76|286|dre:100002407|neuroligin GO:0043296//apical junction complex;GO:0043296//apical junction complex;GO:0043296//apical junction complex;GO:0043296//apical junction complex;GO:0043296//apical junction complex - GO:0009954//proximal/distal pattern formation;GO:0007043//cell-cell junction assembly;GO:0001885//endothelial cell development;GO:0007143//female meiosis;GO:0035150//regulation of tube size;GO:0009954//proximal/distal pattern formation;GO:0007043//cell-cell junction assembly;GO:0001885//endothelial cell development;GO:0007143//female meiosis;GO:0035150//regulation of tube size;GO:0009954//proximal/distal pattern formation;GO:0007043//cell-cell junction assembly;GO:0001885//endothelial cell development;GO:0007143//female meiosis;GO:0035150//regulation of tube size;GO:0009954//proximal/distal pattern formation;GO:0007043//cell-cell junction assembly;GO:0001885//endothelial cell development;GO:0007143//female meiosis;GO:0035150//regulation of tube size;GO:0009954//proximal/distal pattern formation;GO:0007043//cell-cell junction assembly;GO:0001885//endothelial cell development;GO:0007143//female meiosis;GO:0035150//regulation of tube size 19835373 394.00 0.555 0.385 -0.527629325655204 Down 0.123530577202483 33299 2028.66 106.015 87.14 -0.282861386937808 Down 0.499603751155726 CG5080 CG5080, isoform C K10352|1|1e-09|65.1|isc:IscW_ISCW001340|myosin heavy chain;K12478|2|4e-08|60.1|bta:516259|early endosome antigen 1;K11498|3|1e-07|58.9|aga:AgaP_AGAP006472|centromeric protein E - - - 37150 2491.00 0.32 0.92 1.52356195605701 Up 0.289294677057192 CG15086 CG44433 - - - - 40343 627.00 18.9 22.325 0.24027394090015 Up 0.386408664641395 CG12975 CG12975 - - - - 3772715 1023.00 0.07 0.025 -1.48542682717024 Down 0.0803064324395721 His1:CG33825 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 42826 1091.00 18.175 17.57 -0.0488411727985803 Down 0.121879540351341 CG13601 CG13601, isoform B - - - - 12798588 548.28 0.66 0.83 0.330645311988471 Up 0.115539558842953 CG43089 CG43089, isoform C - - - - 2768720 1812.00 7.95 0.01 -9.63481105017172 Down 0.886309602430326 Cyp12d1-d Cyp12d1-d K00517|1|5e-124|444|dme:Dmel_CG6042| [EC:1.14.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 42429 1831.84 29.895 30.515 0.0296143795131766 Up 0.100184916127328 att-ORFA alternative testis transcripts open reading frame A, isoform F K05863|1|4e-23|109|spu:575225|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 38909 1812.00 14.17 10.865 -0.383151583736736 Down 0.454002113327169 Nmt N-myristoyl transferase K00671|1|0.0|958|dme:Dmel_CG7436|glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97] - GO:0016410//N-acyltransferase activity;GO:0016407//acetyltransferase activity GO:0001700//embryonic development via the syncytial blastoderm;GO:0006498//N-terminal protein lipidation 40201 5795.00 12.455 11.91 -0.0645516083767226 Down 0.126931713115837 gig gigas, isoform B K07207|1|0.0|3140|dme:Dmel_CG6975|tuberous sclerosis 2 GO:0044424//intracellular part GO:0008047//enzyme activator activity;GO:0019899//enzyme binding GO:0043087//regulation of GTPase activity;GO:0006909//phagocytosis;GO:0045926//negative regulation of growth;GO:0008283//cell proliferation;GO:0010259//multicellular organismal aging;GO:0009966//regulation of signal transduction;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035467;GO:0007049//cell cycle;GO:0031667//response to nutrient levels 36481 1458.00 0.525 0.13 -2.01380579952503 Down 0.24547615902787 CG10814 CG10814 K00471|1|0.0|841|dme:Dmel_CG10814|gamma-butyrobetaine dioxygenase [EC:1.14.11.1] - GO:0003824//catalytic activity GO:0008152//metabolic process 41891 6970.00 2.785 3.07 0.140561328030147 Up 0.121219125610884 CG5205 CG5205 K01529|1|0.0|4206|dme:Dmel_CG5205| [EC:3.6.1.-] - - - 43529 1758.19 9.005 9.76 0.11615487165661 Up 0.183000924580637 dgt1 dim gamma-tubulin 1, isoform C K11668|1|1e-05|52.0|tad:TRIADDRAFT_60586|INO80 complex subunit D GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0016462//pyrophosphatase activity - 8674059 363.00 0.945 3.375 1.83650126771712 Up 0.535860520406816 Sfp24C1 seminal fluid protein 24C1 - - - - 246509 1606.00 0.83 0.645 -0.363812175923671 Down 0.120558710870427 CG30187 CG30187, isoform D K01321|1|8e-25|115|oaa:100082935|coagulation factor IX (Christmas factor) [EC:3.4.21.22];K09632|3|2e-24|113|hsa:1506|chymotrypsin-like protease [EC:3.4.21.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides - 31834 1232.00 13.715 12.58 -0.124622699968988 Down 0.212059173160745 HP1b heterochromatin protein 1b, isoform C K11585|1|9e-107|386|dsi:Dsim_GD16926|chromobox protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0005488//binding;GO:0005488//binding GO:0006325//chromatin organization;GO:0006325//chromatin organization 37685 1219.00 0.16 0.04 -2 Down 0.1267335886937 CG12782 CG12782 K02180|1|9e-26|117|dre:403012|cell cycle arrest protein BUB3 GO:0043231//intracellular membrane-bounded organelle - - 40651 1889.00 0.305 0.315 0.0465425859370302 Up 0.0419363360190199 CG12147 CG12147 K08957|1|2e-102|373|xtr:407897|casein kinase 1, alpha [EC:2.7.11.1] GO:0005856//cytoskeleton;GO:0000776//kinetochore;GO:0044444//cytoplasmic part;GO:0000267//cell fraction GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0032559 GO:0023060;GO:0007049//cell cycle;GO:0032989;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process 12798049 488.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 12797899 361.00 0.125 0.14 0.16349873228288 Up 0.0504556861709153 34640 944.00 2.135 1.905 -0.164445072127168 Down 0.112534671773874 rho-6 rhomboid-6, isoform C K02857|1|2e-27|122|dan:Dana_GF24766|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity - 38488 3365.77 34.665 33.51 -0.0488880739843161 Down 0.140073966450931 Fit1 fermitin 1, isoform B K06271|1|5e-10|67.4|ecb:100055501|talin - - - 317838 1722.00 0.07 0.035 -1 Down 0.0725795799762251 Ir67c ionotropic receptor 67c - - - - 34208 968.00 0.245 0.315 0.362570079384708 Up 0.0818253863426232 CG32986 CG32986 - - - - 40754 3056.30 3.575 4.475 0.323944440485867 Up 0.266609430722494 NPFR1 neuropeptide F receptor, isoform D K04209|1|0.0|879|dme:Dmel_CG1147|neuropeptide Y receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0030537//larval behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 31618 6015.28 14.23 20.33 0.51467455331825 Up 0.554913485669 C3G C3G ortholog, isoform L K06277|1|0.0|2027|der:Dere_GG17655|Rap guanine nucleotide exchange factor (GEF) 1 - - - 36301 1573.00 3.12 2.66 -0.230119783361059 Down 0.17296262052569 Hen1 Hen1 - - - - 35587 1674.00 96.305 40.765 -1.24027968739168 Down 0.740754193633602 Cyp6a2 cytochrome P450-6a2 K00517|1|0.0|992|dme:Dmel_CG9438| [EC:1.14.-.-] GO:0042598 GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0014074//response to purine-containing compound 48373 820.00 6.39 5.625 -0.183962834842595 Down 0.20991282525426 l(2)k10201 lethal (2) k10201 - GO:0044464//cell part GO:0046914//transition metal ion binding - 36087 1031.00 3.87 3.735 -0.0512253233551731 Down 0.0716219786025624 CG12909 CG12909 - - - - 12798208 722.00 0.06 0.08 0.415037499278844 Up 0.0547483819838859 35602 1311.00 0.88 0.625 -0.49364733397521 Down 0.151201954827632 Spn42De serpin 42De, isoform B K13963|1|2e-67|256|dgr:Dgri_GH19862|serpin B - GO:0004866//endopeptidase inhibitor activity - 35744 2022.00 4.375 4.865 0.153156788061421 Up 0.162693171311584 Kdm4A histone demethylase 4A, isoform B K06709|1|5e-161|568|cqu:CpipJ_CPIJ011492|jumonji domain-containing protein 2 [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity GO:0070076//histone lysine demethylation 39535 3002.00 4.02 4.01 -0.00359326472400822 Down 0.0401862369568089 CG8833 CG8833 K13123|1|0.0|1462|dme:Dmel_CG8833|G patch domain-containing protein 1 GO:0005681//spliceosomal complex GO:0005488//binding GO:0000377 40099 2948.00 0.225 0.28 0.31550182572793 Up 0.0761127988376701 CG14085 CG14085 - - - - 36849 3040.00 11.215 11.87 0.0818903145556344 Up 0.149220710606261 DAT dopamine transporter, isoform B K05336|1|0.0|1266|dme:Dmel_CG8380|solute carrier family 6 (neurotransmitter transporter), invertebrate - - - 14462827 423.00 0.2 0.47 1.23266075679027 Up 0.18187821952186 36495 1015.00 0.155 1.745 3.49288691582278 Up 0.508255184255713 cid centromere identifier K11253|1|4e-16|85.5|aag:AaeL_AAEL009296|histone H3;K11495|2|4e-12|72.4|mdo:100030899|histone H3-like centromeric protein A GO:0000786//nucleosome;GO:0000778//condensed nuclear chromosome kinetochore GO:0003676//nucleic acid binding;GO:0003774//motor activity GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0043623//cellular protein complex assembly;GO:0034728//nucleosome organization 38382 845.00 96.2 118.43 0.299925783285739 Up 0.522189935279355 CG32278 CG32278 - - - - 46008 2813.76 166.385 156.4 -0.0892848643370347 Down 0.239235239730551 Gel gelsolin, isoform L K05768|1|0.0|1528|dme:Dmel_CG1106|gelsolin GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis 246616 406.00 1.83 2.08 0.18473987985705 Up 0.120426627922335 CG30441 CG30441 - - - - 38177 1841.91 111.03 108.695 -0.0306639639504295 Down 0.112435609562805 CG12091 CG12091, isoform B - - GO:0016791//phosphatase activity - 43121 378.00 25.155 16.87 -0.576385215997937 Down 0.595760137366266 Mst57Dc Male-specific transcript 57Dc - - - GO:0019098//reproductive behavior 31154 3550.23 10.93 12.75 0.222203846074316 Up 0.316008453308678 Edem1 Edem1, isoform E K10085|1|0.0|1812|dme:Dmel_CG3810|ER degradation enhancer, mannosidase alpha-like 2 - - - 42082 2435.71 17.465 21.685 0.312230800468238 Up 0.450039624884427 beat-IIb beat-IIb, isoform C - - - - 14462405 544.00 0.3 0.255 -0.234465253637023 Down 0.062012944128913 CG43997 CG43997 - - - - 32316 2200.00 0.525 0.415 -0.339206086319198 Down 0.0962224276845859 Ndc80 Ndc80 K11547|1|2e-25|117|aag:AaeL_AAEL011220|kinetochore protein NDC80;K10388|4|2e-14|81.3|mdo:100014955|plectin GO:0000775//chromosome, centromeric region - GO:0000070//mitotic sister chromatid segregation 43689 2932.00 10.375 11.42 0.138451314241193 Up 0.219951129309206 CG1544 CG1544 K08471|1|0.0|1664|dpo:Dpse_GA13730|gustatory receptor;K10956|3|0.0|700|mcc:696445|protein transport protein SEC61 subunit alpha;K00164|4|1e-164|580|cel:T22B11.5|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] - GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding GO:0006007//glucose catabolic process 2768665 1323.00 0.355 0.735 1.04992522533168 Up 0.215955620129441 CG17207 CG17207 - - - - 40199 438.00 0.27 0.135 -1 Down 0.126172236164311 CG14187 CG14187, isoform B - - GO:0016787//hydrolase activity GO:0044238//primary metabolic process 34970 1063.00 10.635 10.855 0.029539692654472 Up 0.0779949808479725 CG4278 CG4278 - - - - 42028 1811.00 4.485 4.855 0.114363310499931 Up 0.130068683133008 CG10324 CG10324 K13101|1|0.0|706|dme:Dmel_CG10324|G patch domain and KOW motifs-containing protein - - - 19835464 393.00 0.01 0.265 4.7279204545632 Up 0.2511557257958 32666 2673.31 15.21 14.155 -0.10370840381875 Down 0.190826839255052 CG4768 CG4768, isoform B - - - - 43011 1088.00 0.84 0.585 -0.521952703195356 Down 0.15222559767534 fd96Cb forkhead domain 96Cb K09411|1|3e-161|566|dme:Dmel_CG11922|forkhead box protein, other GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0043566//structure-specific DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction 19834785 1449.00 0.035 0.135 1.94753258010586 Up 0.11260071324792 40940 4460.76 11.105 10.375 -0.0980980564253313 Down 0.169330339453177 dsx doublesex, isoform F - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0003723//RNA binding GO:0007423//sensory organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016198//axon choice point recognition;GO:0008049//male courtship behavior;GO:0000377;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0007560//imaginal disc morphogenesis;GO:0007484//imaginal disc-derived genitalia development;GO:0007487//analia development;GO:0048070//regulation of developmental pigmentation;GO:0046620//regulation of organ growth;GO:0007423//sensory organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016198//axon choice point recognition;GO:0008049//male courtship behavior;GO:0000377;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0007560//imaginal disc morphogenesis;GO:0007484//imaginal disc-derived genitalia development;GO:0007487//analia development;GO:0048070//regulation of developmental pigmentation;GO:0046620//regulation of organ growth;GO:0007423//sensory organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016198//axon choice point recognition;GO:0008049//male courtship behavior;GO:0000377;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0007560//imaginal disc morphogenesis;GO:0007484//imaginal disc-derived genitalia development;GO:0007487//analia development;GO:0048070//regulation of developmental pigmentation;GO:0046620//regulation of organ growth 33514 2431.75 16.385 16.48 0.00834056964045885 Up 0.0547483819838859 CG3605 CG3605, isoform B K12829|1|0.0|1167|dme:Dmel_CG3605|splicing factor 3B subunit 2 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex - GO:0000377 43614 1529.82 38.65 49.995 0.371315404019195 Up 0.546295073306036 CG15537 CG15537, isoform C - - - - 32478 3484.00 3.115 3.445 0.145271819680289 Up 0.13426231673491 Grip128 Grip128 - GO:0000931//gamma-tubulin large complex GO:0015631//tubulin binding GO:0048610//cellular process involved in reproduction;GO:0007056//spindle assembly involved in female meiosis;GO:0000087//M phase of mitotic cell cycle;GO:0033206//cytokinesis after meiosis 19834777 633.00 3.155 3.32 0.0735432363643758 Up 0.0821225729758288 39651 2083.62 202.825 172.305 -0.235270921658965 Down 0.468168009509972 Pdi protein disulfide isomerase, isoform E K09580|1|0.0|880|dme:Dmel_CG6988|protein disulfide-isomerase A1 [EC:5.3.4.1] GO:0031967;GO:0012505//endomembrane system;GO:0044432//endoplasmic reticulum part;GO:0044297//cell body GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis 32334 902.72 20.845 17.675 -0.237991157111628 Down 0.380233786818122 CG11134 CG11134, isoform B K08964|1|2e-133|474|dsi:Dsim_GD17142|methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109] GO:0044424//intracellular part GO:0043169//cation binding;GO:0005515//protein binding;GO:0016836//hydro-lyase activity GO:0071265;GO:0012501//programmed cell death 42377 2062.00 0.325 0.23 -0.498805856971442 Down 0.0928543125082552 CG4459 CG4459 K08202|1|5e-21|102|ame:412399|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5;K08209|2|1e-20|101|gga:420423|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13;K08210|3|3e-20|100|cfa:485588|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 14;K08204|4|3e-20|100|rno:89776|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 7;K08200|5|8e-20|99.0|cfa:476261|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3 - - GO:0006810//transport 14462409 308.00 0.15 0.2 0.415037499278844 Up 0.073702285035002 38251 1413.00 3.01 2.85 -0.0788015677075979 Down 0.0821886144498745 Tmhs tetraspan membrane protein in hair cell stereocilia ortholog, isoform B - - - - 42895 978.00 0.045 0.1 1.15200309344505 Up 0.0796790384361379 CG5715 CG5715 K08076|1|6e-41|169|cel:C05D11.6|astacin [EC:3.4.24.21];K08606|5|3e-36|153|cfa:490497|meprin A, beta [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006909//phagocytosis 43557 1794.66 11.415 13.08 0.196431681273381 Up 0.296592259939242 CG11504 CG11504, isoform C K00738|1|6e-09|62.8|tca:654917|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145] - - - 19835614 446.00 0.19 0.11 -0.788495894806288 Down 0.0929533747193237 34143 1842.86 229.475 268.53 0.226746285426476 Up 0.460507198520671 CG7781 CG7781, isoform B - - - - 41491 3637.41 11.47 12.07 0.0735602847391965 Up 0.137333245278035 svp seven up, isoform E K14032|1|0.0|638|dya:Dyak_GE26169|nuclear receptor subfamily 2 group F member 3 - - - 19835521 752.00 6.815 8.425 0.305963029264011 Up 0.339122969224673 35080 1317.00 0.035 0.035 0 - 0.0382380134724607 CG15153 CG15153 - - - - 31024 2840.00 6.665 5.425 -0.296981737757131 Down 0.302965262184652 tw protein O-mannosyltransferase 2, isoform B K00728|1|0.0|1507|dme:Dmel_CG12311|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] - - - 33214 604.96 848.615 955.17 0.170647345387563 Up 0.389743759080703 RpLP1 ribosomal protein LP1, isoform B K02942|1|1e-35|149|dya:Dyak_GE16802|large subunit ribosomal protein LP1 GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation 32640 6897.63 4.175 3.21 -0.379202900239111 Down 0.284308545766742 r rudimentary, isoform D K11540|1|0.0|4360|dme:Dmel_CG18572|carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] GO:0044444//cytoplasmic part GO:0032561//guanyl ribonucleotide binding;GO:0016597//amino acid binding;GO:0004086;GO:0032559;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016743//carboxyl- or carbamoyltransferase activity GO:0001751//compound eye photoreceptor cell differentiation;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0008360//regulation of cell shape;GO:0006220//pyrimidine nucleotide metabolic process;GO:0043408//regulation of MAPK cascade;GO:0006929//substrate-dependent cell migration;GO:0009064//glutamine family amino acid metabolic process;GO:0019827//stem cell maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000904//cell morphogenesis involved in differentiation 38527 1050.08 21.935 22.15 0.0140719924231502 Up 0.0612864879144102 TfIIEbeta transcription factor IIEbeta, isoform B K03137|1|7e-124|443|dsi:Dsim_GD13833|transcription initiation factor TFIIE beta subunit GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0030528//transcription regulator activity GO:0006352//DNA-dependent transcription, initiation;GO:0006352//DNA-dependent transcription, initiation 14462667 996.00 0.045 0.265 2.55799545312089 Up 0.180458327829877 34781 1179.00 16.35 15.005 -0.123847316787157 Down 0.2242768458592 CG16890 CG16890, isoform D K13121|1|4e-89|326|dme:Dmel_CG16890|protein FRA10AC1 - - - 3885607 2583.24 12.48 18.08 0.534776743552939 Up 0.551248183859464 CG33995 CG33995, isoform C K10380|1|2e-13|78.6|dya:Dyak_GE14529|ankyrin - - - 19836084 3758.00 1.035 1.09 0.0746973672776008 Up 0.0561022322018227 49580 3610.00 54.93 47.44 -0.21149028197249 Down 0.406584334962356 Invadolysin invadolysin K13539|1|0.0|1417|dme:Dmel_CG3953|leishmanolysin-like peptidase [EC:3.4.24.-] GO:0044424//intracellular part GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0016568//chromatin modification;GO:0007276//gamete generation;GO:0007417//central nervous system development;GO:0000070//mitotic sister chromatid segregation;GO:0051297//centrosome organization;GO:0019538//protein metabolic process;GO:0007051//spindle organization;GO:0048513//organ development;GO:0045137//development of primary sexual characteristics;GO:0030071//regulation of mitotic metaphase/anaphase transition 3772236 553.00 27.765 16.475 -0.752988930696316 Down 0.643739268260468 38311 1817.00 34.315 20.025 -0.777037112047512 Down 0.659886408664641 Cyp4d20 Cyp4d20 K00517|1|0.0|652|dme:Dmel_CG6730| [EC:1.14.-.-] GO:0044424//intracellular part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0022414//reproductive process 44131 2884.00 29.97 30.39 0.02007759100872 Up 0.0811319508651433 Mkrn1 makorin 1, isoform C - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 40901 2017.00 146.835 124.39 -0.239325385447894 Down 0.464304583278299 alpha-Est7 alpha-Esterase-7 K01044|1|0.0|1181|dme:Dmel_CG1112|carboxylesterase [EC:3.1.1.1];K03927|2|0.0|1008|dmo:Dmoj_GI23478|carboxylesterase type B [EC:3.1.1.1];K01066|5|3e-153|542|dpo:Dpse_GA10843|esterase / lipase [EC:3.1.1.-] GO:0044444//cytoplasmic part GO:0016788//hydrolase activity, acting on ester bonds - 10178824 448.01 8.915 12.92 0.53529936706893 Up 0.515552767137763 CG42688 CG42688, isoform B - - - - 34322 2381.22 47.36 31.365 -0.594513518318214 Down 0.634130233786818 CG5853 CG5853, isoform C K05680|1|4e-139|495|mdo:100031232|ATP-binding cassette, subfamily G (WHITE), member 4 GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006909//phagocytosis 14462628 400.00 0.11 0.24 1.12553088208386 Up 0.122407872143706 43852 4738.12 6.86 8.83 0.364204861475654 Up 0.38171971998415 a arc, isoform D K06095|1|4e-16|88.2|tgu:100230229|multiple PDZ domain protein GO:0044459//plasma membrane part;GO:0044459//plasma membrane part;GO:0044459//plasma membrane part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0001654//eye development;GO:0001654//eye development;GO:0001654//eye development 42835 1099.93 71.805 68.65 -0.0648245864064595 Down 0.173094703473782 AP-1sigma adaptor protein complex 1, sigma subunit, isoform D K12394|1|6e-87|320|dpe:Dper_GL23383|AP-1 complex subunit sigma 1/2 GO:0012510//trans-Golgi network transport vesicle membrane;GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding;GO:0022892 GO:0006900//membrane budding;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport 317829 2382.00 1.16 1.535 0.404113850242607 Up 0.179863954563466 CG32026 CG32026 K00030|1|0.0|667|dme:Dmel_CG32026|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0009060//aerobic respiration 40959 2375.00 14.795 14.905 0.0106866787972475 Up 0.0555739004094571 CG7878 CG7878 K12823|1|1e-137|490|ssc:100155174|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13];K13178|2|2e-96|353|xtr:549535|ATP-dependent RNA helicase DDX17 [EC:3.6.1.-] - GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled - 19836171 5259.00 0.365 0.79 1.11395618929709 Up 0.230616827367587 - CG44434 - - - - 14462464 334.00 1.045 5.55 2.40898482915659 Up 0.647140404173821 CG44142 CG44142 - - - - 38900 1734.00 1.2 1.08 -0.15200309344505 Down 0.0855237088891824 ldbr lariat debranching enzyme - GO:0043231//intracellular membrane-bounded organelle GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters GO:0008380//RNA splicing 34601 1137.00 0.04 0.01 -2 Down 0.0694426099590543 Or33a odorant receptor 33a K08471|1|0.0|726|dme:Dmel_CG16960|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 42000 1194.79 19.2 17.065 -0.170065896509654 Down 0.299266939638093 CSN5 COP9 complex homolog subunit 5, isoform B K09613|1|1e-180|632|dse:Dsec_GM15160|COP9 signalosome complex subunit 5 [EC:3.4.-.-] - - - 38887 643.00 15.77 20.165 0.354670745615366 Up 0.472526746796989 HP4 heterochromatin protein 4, isoform B - GO:0005700//polytene chromosome;GO:0000781//chromosome, telomeric region;GO:0031981//nuclear lumen;GO:0005700//polytene chromosome;GO:0000781//chromosome, telomeric region;GO:0031981//nuclear lumen - GO:0051276//chromosome organization;GO:0051276//chromosome organization 33527 855.00 0.825 0.92 0.157239741811197 Up 0.0800752872804121 CG15403 CG15403 - - - - 39353 1514.00 0.285 0.155 -0.878693703777866 Down 0.117058512746004 CG7252 CG7252 K01873|1|1e-16|87.8|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K01183|3|2e-07|57.4|dme:Dmel_CG18140|chitinase [EC:3.2.1.14];K05030|5|1e-06|55.1|cin:100175971|calcium-activated chloride channel family member 4 - GO:0030247//polysaccharide binding GO:0006022 19835287 504.00 0.17 0.095 -0.839535327806754 Down 0.0879012019548276 32051 558.73 9.94 11.61 0.22405021530328 Up 0.306267335886937 CG15199 CG15199, isoform B - - - - 35695 1757.00 1.47 2.025 0.462105752935623 Up 0.225531633866068 CG1360 CG1360 - - - - 40643 1260.00 10.395 10.69 0.040372094862121 Up 0.0932175406155065 CG14667 CG14667 K09228|1|1e-21|104|bta:515089|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0046914//transition metal ion binding;GO:0051287//NAD binding GO:0016458//gene silencing;GO:0006464//cellular protein modification process 14462683 1241.00 0.23 0.145 -0.66558096092944 Down 0.0905428609166557 41452 1131.00 20.77 25.045 0.270021395413254 Up 0.424646678113855 CG18547 CG18547 K04884|1|2e-11|70.1|xtr:779823|potassium voltage-gated channel Shaker-related subfamily A, beta member 3;K04883|2|3e-10|66.2|bfo:BRAFLDRAFT_67317|potassium voltage-gated channel Shaker-related subfamily A, beta member 2 - GO:0003824//catalytic activity GO:0030001//metal ion transport;GO:0008152//metabolic process 41214 900.00 1.085 1.99 0.87507338809917 Up 0.321555937128517 CG9458 CG9458 K00680|1|2e-91|335|dme:Dmel_CG9459| [EC:2.3.1.-];K10250|4|1e-34|146|dre:327274|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane - - 40513 2011.66 6.66 7.79 0.226101150990407 Up 0.267104741777836 CG12768 CG12768, isoform D - - - - 19835433 718.00 0.065 0.08 0.299560281858908 Up 0.053394531765949 36875 723.00 3.26 4.05 0.313049943540909 Up 0.24791969356756 CG5267 CG5267 - - - - 43015 3361.56 13.84 7.74 -0.838438471492314 Down 0.603883238673887 CG31108 CG31108, isoform B K05755|1|6e-21|103|ecb:100058358|actin related protein 2/3 complex, subunit 4;K06047|2|4e-16|87.8|cfa:483065|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0043412//macromolecule modification 37703 1751.00 16.6 18.69 0.171083327510871 Up 0.297318716153745 yellow-d yellow-d - - - - 5740436 548.00 0.375 1.08 1.52606881166759 Up 0.313201690661736 CG34298 CG34298 - - - - 41443 2875.00 47.92 65.585 0.452737984458664 Up 0.598071588957865 CG31211 CG31211, isoform C K13170|1|4e-151|291|dme:Dmel_CG31211|splicing factor, arginine/serine-rich 18 - - - 32990 1803.11 41.27 36.585 -0.173841179489694 Down 0.345132743362832 parvin parvin, isoform B K06275|1|0.0|689|dme:Dmel_CG32528|parvin - - - 32378 2894.00 50.075 79.445 0.665865908039328 Up 0.668141592920354 Fbxl4 F box and leucine-rich-repeat gene 4 K10270|1|0.0|1283|dme:Dmel_CG1839|F-box and leucine-rich repeat protein 4 - - - 49803 1297.00 7.79 8.46 0.119034335058281 Up 0.17434949148065 Spn55B serpin 55B K13963|1|0.0|641|dse:Dsec_GM21844|serpin B - GO:0004866//endopeptidase inhibitor activity - 14462757 417.00 1.11 0.455 -1.28662122615141 Down 0.293488310659094 32108 2160.00 205.695 301.99 0.553994051903553 Up 0.661537445515784 CG1561 CG1561 - - - - 326257 872.69 7.43 10.395 0.484455642319774 Up 0.464998018755779 CG33108 CG33108, isoform B K12622|1|4e-44|177|dwi:Dwil_GK14178|U6 snRNA-associated Sm-like protein LSm3 - - - 34221 1433.97 11.23 9.08 -0.306593725109686 Down 0.377394003434157 CG13101 CG13101, isoform B - - - - 40691 999.00 1.525 1.565 0.0373534144823696 Up 0.050752872804121 CG31546 CG31546 K11147|1|2e-24|112|aag:AaeL_AAEL006224|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 19835001 451.00 0.205 0.01 -4.35755200461808 Down 0.213941355171047 40602 2962.28 13.06 14.21 0.12175165769635 Up 0.21328094043059 CG14657 CG14657, isoform D K12811|1|9e-06|52.8|hmg:100202415|ATP-dependent RNA helicase DDX46/PRP5 [EC:3.6.4.13] - - - 40952 1124.00 9.51 7.985 -0.252152933449331 Down 0.307819310527011 CG10903 CG10903, isoform B K00599|1|5e-89|327|mdo:100018676| [EC:2.1.1.-] - GO:0016741 - 34956 4117.63 22.625 25.56 0.175970044089064 Up 0.330570598335755 crp cropped, isoform B K09108|1|2e-23|112|dre:100318080|transcription factor AP-4 - GO:0030528//transcription regulator activity;GO:0005488//binding - 19835300 3167.00 1.595 1.45 -0.137503523749935 Down 0.0911702549200898 42359 991.00 11.72 11.58 -0.017337316433011 Down 0.063333773609827 CG11447 CG11447 K02427|1|2e-142|505|dme:Dmel_CG11447|ribosomal RNA large subunit methyltransferase E [EC:2.1.1.-] GO:0044424//intracellular part GO:0005488//binding;GO:0008171//O-methyltransferase activity GO:0006730//one-carbon metabolic process;GO:0000154//rRNA modification 33889 2309.00 2.945 2.48 -0.247927513443586 Down 0.178014793290186 CG9505 CG9505 K01389|1|3e-27|124|dme:Dmel_CG3775|neprilysin [EC:3.4.24.11];K08635|2|1e-19|98.6|cqu:CpipJ_CPIJ002051|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 3354988 1569.50 14.79 18.98 0.359857939922042 Up 0.472526746796989 CG17163 CG17163, isoform B - - - - 44095 3874.20 32.035 22.07 -0.537562360884645 Down 0.599887729494122 fus fusilli, isoform H K12898|1|4e-31|137|tad:TRIADDRAFT_29141|heterogeneous nuclear ribonucleoprotein F/H - GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 14462578 649.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 34270 711.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 Cpr30B cuticular protein 30B - - GO:0042302//structural constituent of cuticle - 38929 1633.00 0.165 0.03 -2.4594316186373 Down 0.135318980319641 CG7201 CG7201, isoform B - - - - 42467 2191.31 102.52 112.765 0.137413969793915 Up 0.327829877162858 Synd syndapin, isoform D K10408|1|4e-120|432|tca:664324|dynein heavy chain, axonemal;K12804|3|3e-13|77.4|dre:571331|proline-serine-threonine phosphatase interacting protein 1 - - GO:0006897//endocytosis 40805 1398.00 0.305 0.185 -0.721283971933937 Down 0.108869369964338 CG1138 CG1138 - - - - 34503 1949.00 22.045 28.535 0.372281086060703 Up 0.514991414608374 Dnz1 DNZDHHC/NEW1 zinc finger protein 11 - - GO:0046914//transition metal ion binding - 41557 1774.00 4.765 3.43 -0.474267637737129 Down 0.345661075155197 CG6753 CG6753 K01046|1|0.0|814|dme:Dmel_CG6753|triacylglycerol lipase [EC:3.1.1.3] - - - 32146 1466.59 32.36 16.81 -0.94489188319381 Down 0.680821555937129 CG15739 CG15739, isoform B K01101|1|3e-163|575|dme:Dmel_CG15739|4-nitrophenyl phosphatase [EC:3.1.3.41] - GO:0016791//phosphatase activity - 32642 812.93 14.85 13.91 -0.0943405111458889 Down 0.175802403909655 CG13012 CG13012, isoform E - - - - 43165 1202.00 151.31 154.93 0.0341091909594465 Up 0.114152687887994 Dak1 Dak1 K13800|1|2e-131|468|dme:Dmel_CG6092|UMP-CMP kinase [EC:2.7.4.- 2.7.4.14] GO:0044424//intracellular part GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019201//nucleotide kinase activity;GO:0032559 GO:0009117//nucleotide metabolic process 14462866 840.00 0.535 0.895 0.74234879086311 Up 0.195251618016114 38451 2095.18 2.68 2.815 0.0709019216224572 Up 0.0762779025227843 Awh arrowhead, isoform D K09375|1|4e-110|399|aga:AgaP_AGAP006540|LIM homeobox protein 6/8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 39144 1834.00 2.085 1.46 -0.514079014564647 Down 0.24154669132215 CG6749 CG6749 K13023|1|1e-34|147|oaa:100081004|carboxypeptidase N regulatory subunit - GO:0005488//binding - 42228 1287.00 0.065 0.235 1.85414913353655 Up 0.148890503236032 CG7691 CG7691 K09218|1|2e-16|87.0|spu:378469|snail, invertebrate;K09219|4|5e-16|85.5|mdo:100012171|scratch GO:0044464//cell part GO:0046914//transition metal ion binding - 37756 1139.00 0.47 0.455 -0.0467942114789409 Down 0.0419363360190199 CG18128 CG18128 K03783|1|0.0|632|dme:Dmel_CG18128|purine-nucleoside phosphorylase [EC:2.4.2.1] - GO:0016763//transferase activity, transferring pentosyl groups GO:0055086//nucleobase-containing small molecule metabolic process 39362 4246.00 0.125 0.175 0.485426827170242 Up 0.0743296790384361 CG6938 CG6938, isoform C K13982|1|2e-26|121|dgr:Dgri_GH10918|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13];K05169|2|3e-17|91.7|ptr:743996|single Ig IL-1R-related molecule - - - 14462353 1652.00 1.99 2.41 0.276264715686313 Up 0.174151367058513 39696 1769.36 9.38 5.665 -0.727511966694861 Down 0.534539690925901 comm3 comm3, isoform E - - - GO:0012501//programmed cell death;GO:0012501//programmed cell death 41636 3094.59 27.18 22.39 -0.279690927914794 Down 0.440496631884824 CG32473 CG32473, isoform C K11141|1|0.0|1757|dme:Dmel_CG32473|glutamyl aminopeptidase [EC:3.4.11.7] - - - 43692 1135.00 3.55 3.08 -0.204888673697143 Down 0.169990754193634 CG15561 CG15561 K11135|1|3e-08|59.3|cqu:CpipJ_CPIJ017220|Pin2-interacting protein X1 GO:0044464//cell part GO:0005488//binding - 19834772 1620.00 0.145 0.185 0.351472370501378 Up 0.0666688680491349 40081 3846.08 22.27 29.52 0.406591163272606 Up 0.537511557257958 Mkp3 Mitogen-activated protein kinase phosphatase 3, isoform D K04459|1|7e-141|501|dme:Dmel_CG14080|dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 19835045 871.00 0.05 0.105 1.0703893278914 Up 0.0856557918372738 42769 1680.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 Ir94h ionotropic receptor 94h - GO:0044464//cell part GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity - 117331 615.99 17.895 19.065 0.0913699873097306 Up 0.187260599656584 ventrally-expressed-protein-D ventrally-expressed-protein-D, isoform C - - - - 50287 513.00 0.64 1.52 1.24792751344359 Up 0.335919957733457 CG14113 CG14113 - - - - 39117 6226.00 0.79 0.645 -0.292553492753849 Down 0.104939902258618 CG3280 CG3280 - - - - 46121 819.00 41.3 45.63 0.143840872138845 Up 0.30653150178312 l(3)01239 lethal (3) 01239, isoform B K09549|1|4e-75|281|dme:Dmel_CG6302|prefoldin subunit 2 GO:0043234//protein complex GO:0005515//protein binding GO:0006457//protein folding;GO:0006909//phagocytosis 40548 2412.00 5.37 6.215 0.210832303067073 Up 0.229560163782856 Skp2 Skp2, isoform E K03875|1|0.0|858|dsi:Dsim_GD19685|F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2) - - GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 41462 2133.47 0.09 0.265 1.55799545312089 Up 0.150112270505878 CG31358 CG31358, isoform B K03364|1|2e-12|75.5|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0044464//cell part - - 42916 1139.00 0.04 0.01 -2 Down 0.0694426099590543 CG13615 CG13615 - - - - 49780 1327.00 0.09 0.07 -0.362570079384708 Down 0.0544181746136574 PpD6 protein phosphatase D6 K01090|1|0.0|688|dme:Dmel_CG8822|protein phosphatase [EC:3.1.3.16];K06269|2|2e-112|405|oaa:100074395|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 246383 1327.00 0.625 0.79 0.337996463515016 Up 0.116034869898296 CG30001 CG30001 - - - - 38556 765.00 3.845 0.63 -2.60955986446191 Down 0.607614581957469 CG13721 CG13721 - - - - 39644 2457.00 17.415 15.705 -0.149106529934758 Down 0.266774534407608 Aats-gly Glycyl-tRNA synthetase, isoform C K01880|1|0.0|1410|dya:Dyak_GE22046|glycyl-tRNA synthetase [EC:6.1.1.14] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 31075 5234.30 21.075 23.24 0.141077437575084 Up 0.273940034341566 DAAM dishevelled associated activator of morphogenesis, isoform G K04512|1|0.0|2281|der:Dere_GG12709|dishevelled associated activator of morphogenesis GO:0008287//protein serine/threonine phosphatase complex;GO:0030426//growth cone GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0004722//protein serine/threonine phosphatase activity GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0060491//regulation of cell projection assembly;GO:0007424//open tracheal system development;GO:0006464//cellular protein modification process 34524 2825.00 0.57 0.94 0.721698837512895 Up 0.195614846123365 aub aubergine, isoform C K02156|1|0.0|1603|dme:Dmel_CG6137|aubergine GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006413//translational initiation;GO:0016246//RNA interference;GO:0007315//pole plasm assembly;GO:0010528;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0045727//positive regulation of translation;GO:0044087;GO:0000377;GO:0051237//maintenance of RNA location;GO:0006413//translational initiation;GO:0016246//RNA interference;GO:0007315//pole plasm assembly;GO:0010528;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0045727//positive regulation of translation;GO:0044087;GO:0000377;GO:0051237//maintenance of RNA location 40819 1097.00 4.725 12.85 1.44338212497281 Up 0.672632413155462 Ccp84Ag Ccp84Ag - - GO:0042302//structural constituent of cuticle - 41547 1033.00 48.175 63.2 0.391639891881382 Up 0.567395324263638 hug hugin - - - - 43385 2011.37 103.645 107.365 0.0508732444661098 Up 0.154966318848237 Hrb98DE heterogeneous nuclear ribonucleoprotein at 98DE, isoform F K12741|1|4e-105|382|der:Dere_GG11603|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0005875//microtubule associated complex;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0005875//microtubule associated complex;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0005875//microtubule associated complex;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0005875//microtubule associated complex;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0005875//microtubule associated complex;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0005875//microtubule associated complex;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003774//motor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003774//motor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003774//motor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003774//motor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003774//motor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003774//motor activity GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007017//microtubule-based process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007017//microtubule-based process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007017//microtubule-based process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007017//microtubule-based process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007017//microtubule-based process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007017//microtubule-based process 50358 554.71 1.98 2.06 0.0571439071036088 Up 0.0625412759212786 Diedel3 diedel 3, isoform B - - - - 34755 825.00 0.855 1.485 0.796466605914868 Up 0.264727248712191 CG16957 CG16957, isoform B - - GO:0005506//iron ion binding - 5740676 1274.00 1.53 5.405 1.820762965042 Up 0.607482499009378 inaF-A inaF-A - GO:0044464//cell part GO:0016247//channel regulator activity;GO:0005488//binding GO:0016057//regulation of membrane potential in photoreceptor cell 19836048 249.00 13.595 6.19 -1.1350648368105 Down 0.64723946638489 3772502 595.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 His2B:CG33894 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 12798042 836.00 0.245 0.48 0.970252656605948 Up 0.162561088363492 3772337 192.00 14.29 23.265 0.703155270661431 Up 0.620096420552107 40929 2748.00 5.88 6.245 0.0868854167715925 Up 0.121681415929204 CG10092 CG10092, isoform B K01887|1|0.0|1095|dme:Dmel_CG10092|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0043231//intracellular membrane-bounded organelle GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 36670 4298.57 7.21 8.84 0.294047110150609 Up 0.333377360982697 Lap1 Lap1, isoform B K01768|1|0.0|1544|dme:Dmel_CG10255|adenylate cyclase [EC:4.6.1.1];K12796|3|8e-110|399|ame:410256|erbb2-interacting protein GO:0070161;GO:0070161 GO:0005488//binding;GO:0005488//binding GO:0009987//cellular process;GO:0006810//transport;GO:0009987//cellular process;GO:0006810//transport 36524 2050.41 11.25 17.945 0.673656921711678 Up 0.590972130497953 S-Lap7 Sperm-Leucylaminopeptidase 7, isoform B K01255|1|0.0|1017|dme:Dmel_CG13340|leucyl aminopeptidase [EC:3.4.11.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 34477 1184.00 17.675 18.595 0.0732045329152266 Up 0.156089023907014 CG6443 CG6443 - - - - 40589 2840.08 121.555 122.725 0.0138199288137148 Up 0.0689472989037115 tacc transforming acidic coiled-coil protein, isoform N K12478|1|8e-06|52.4|mcc:710381|early endosome antigen 1 GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome;GO:0005818//aster;GO:0005813//centrosome GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0007019//microtubule depolymerization;GO:0007097//nuclear migration;GO:0007126//meiosis;GO:0000741//karyogamy;GO:0000087//M phase of mitotic cell cycle;GO:0033036 14462626 484.00 0.995 0.495 -1.00726800046404 Down 0.247985735041606 12797874 832.00 0.475 0.475 0 - 0.0382380134724607 246389 873.00 17.17 17.905 0.0604724793183902 Up 0.138984282129177 CG30010 CG30010, isoform B - - - - 44873 1490.00 0.44 0.45 0.0324214776923774 Up 0.0416391493858143 Gr5a gustatory receptor 5a K08471|1|0.0|818|dme:Dmel_CG15779|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0050909//sensory perception of taste;GO:0034285 43195 1910.00 0.105 0.07 -0.584962500721156 Down 0.0687491744815744 CG14238 CG14238 - - - - 32353 12571.36 15.6 16.345 0.0673033480176551 Up 0.147338528595958 mamo maternal gene required for meiosis, isoform I K09237|1|2e-34|149|tca:659978|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0005488//binding;GO:0046914//transition metal ion binding - 40241 1941.26 81.885 76.96 -0.0894903986975318 Down 0.230847972526747 CG5618 CG5618, isoform E K01594|1|0.0|888|dpo:Dpse_GA19009|sulfinoalanine decarboxylase [EC:4.1.1.29] GO:0044424//intracellular part GO:0048037//cofactor binding;GO:0016830//carbon-carbon lyase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0043436 34406 1255.00 23.28 19.045 -0.289678770344944 Down 0.437755910711927 CG5056 CG5056 - - - - 40677 831.00 6.845 8.565 0.3234027048261 Up 0.352034077400608 rev7 rev7 K13728|1|7e-100|363|dme:Dmel_CG2948|mitotic spindle assembly checkpoint protein MAD2B - - GO:0043085//positive regulation of catalytic activity;GO:0000087//M phase of mitotic cell cycle 32467 2581.75 14.84 17.57 0.243623099387573 Up 0.367190595694096 CG9164 CG9164, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups - 41348 921.17 13.35 19.41 0.539960376138747 Up 0.561913881917844 scpr-C SCP-containing protein C, isoform B K00747|1|2e-08|60.1|tca:656110|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] - - - 32920 4429.74 12.29 16.225 0.400733562513839 Up 0.479362039360719 vav Vav ortholog, isoform D K05730|1|0.0|1540|dya:Dyak_GE15839|vav oncogene GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005099//Ras GTPase activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005099//Ras GTPase activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005099//Ras GTPase activator activity GO:0065008;GO:0007266//Rho protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0065008;GO:0007266//Rho protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0065008;GO:0007266//Rho protein signal transduction;GO:0030036//actin cytoskeleton organization 39174 843.00 13.725 13.52 -0.0217109976103766 Down 0.0702351076476027 CG6674 CG6674, isoform B - - - - 12798344 740.00 0.06 0.065 0.115477217419936 Up 0.0441487253995509 42922 2710.20 91.2 76.135 -0.260473997227744 Down 0.475531633866068 Pp1alpha-96A protein phosphatase 1alpha at 96A, isoform B K06269|1|0.0|644|dse:Dsec_GM26605|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 39959 1452.00 8.435 2.205 -1.93560941273004 Down 0.668967111345925 Jon74E jonah 74E, isoform B K01310|1|2e-133|474|dme:Dmel_CG6298|chymotrypsin [EC:3.4.21.1];K01362|5|3e-35|148|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 41030 1254.00 12.5 14.83 0.246590502905181 Up 0.35622771100251 CG8043 CG8043 K06980|1|0.0|695|dme:Dmel_CG8043| GO:0044424//intracellular part GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process 31772 2521.00 18.83 18.87 0.00306142298621708 Up 0.0434552899220711 CG11190 CG11190 K05292|1|0.0|1207|dme:Dmel_CG11190|phosphatidylinositol glycan, class T GO:0030176//integral to endoplasmic reticulum membrane - - 38634 1075.00 0.04 0.01 -2 Down 0.0694426099590543 CG10591 CG10591 - - - - 41078 1191.15 26.7 23.72 -0.170735732028913 Down 0.323405098401796 CG11980 CG11980, isoform C - - - - 43838 5646.22 24.565 31.775 0.371287886141303 Up 0.522288997490424 mGluRA metabotropic glutamate receptor, isoform D K04611|1|0.0|1912|dme:Dmel_CG11144|glutamate receptor, metabotropic, invertebrate - - - 35784 1907.00 7.985 8.23 0.0436000230103931 Up 0.0868445383700964 Nup50 nucleoporin 50kD - - - - 19835105 205.00 0.245 0.01 -4.61470984411521 Down 0.239499405626734 38587 1536.00 1.04 0.655 -0.667016716603642 Down 0.194360058116497 CG13705 CG13705 - - - - 14462879 1204.00 1.435 2.73 0.927850214244165 Up 0.385318980319641 CG44004 CG44004, isoform C - - - - 19836072 601.00 0.28 1.785 2.6724253419715 Up 0.474078721437062 3346238 6096.32 32.55 29.12 -0.160647187854302 Down 0.319871879540351 form3 formin 3, isoform B K04512|1|8e-41|170|mdo:100026517|dishevelled associated activator of morphogenesis GO:0044423;GO:0044423 GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding GO:0060541//respiratory system development;GO:0007010//cytoskeleton organization;GO:0019063;GO:0035146;GO:0060541//respiratory system development;GO:0007010//cytoskeleton organization;GO:0019063;GO:0035146 318781 1689.48 0.275 0.375 0.447458976971221 Up 0.0956610751551975 CG31524 CG31524, isoform B K00472|1|0.0|1013|dme:Dmel_CG31524|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process;GO:0008152//metabolic process 44274 4884.00 10.725 12.465 0.216905235104593 Up 0.311154404966319 disp dispatched K06225|1|3e-06|55.5|cqu:CpipJ_CPIJ003243|patched 1 GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0008354//germ cell migration;GO:0016192//vesicle-mediated transport 50402 1085.00 2.445 1.765 -0.470166281681053 Down 0.249702813366794 CG15345 CG15345 - - - - 33230 5307.45 9.4 9.395 -0.000767595144944381 Down 0.0401862369568089 rempA reduced mechanoreceptor potential A, isoform C K05770|1|3e-100|244|dsi:Dsim_GD23032|benzodiazapine receptor - - GO:0010970//microtubule-based transport;GO:0042384//cilium assembly;GO:0010970//microtubule-based transport;GO:0042384//cilium assembly 43466 2746.28 0.505 0.53 0.0697089718114045 Up 0.049432043323207 stg string, isoform B K01104|1|0.0|833|dme:Dmel_CG1395|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0004725//protein tyrosine phosphatase activity GO:0009888//tissue development;GO:0048598//embryonic morphogenesis;GO:0060541//respiratory system development;GO:0007399//nervous system development;GO:0007017//microtubule-based process;GO:0007067//mitosis;GO:0006464//cellular protein modification process 3772547 1413.07 157.42 162.235 0.0434662500521759 Up 0.136243560956281 37894 1456.00 94.9 64.725 -0.552085027120998 Down 0.645819574692907 Mov34 regulatory particle non-ATPase 8, isoform C K03038|1|3e-159|561|dya:Dyak_GE14400|26S proteasome regulatory subunit N8 GO:0043005//neuron projection;GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process;GO:0007052//mitotic spindle organization 31682 2688.00 9.78 9.785 0.000737385674570083 Up 0.0382380134724607 CG12155 CG12155 - - - - 19835653 296.00 0.155 0.21 0.438121112391885 Up 0.0738343679830934 31107 6461.60 13.305 17.545 0.399091437379947 Up 0.486923788138951 Nmdar2 NMDA receptor 2, isoform G K05314|1|0.0|2052|dme:Dmel_CG33513|glutamate receptor, ionotropic, N-methyl-D-aspartate 2, invertebrate GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 37304 3567.67 37.16 47.235 0.346105756473913 Up 0.531336679434685 CG8920 CG8920, isoform F - GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 326165 4820.14 54.73 63.8 0.221224567444743 Up 0.423358869369964 CG42784 CG42784, isoform I - - - - 19834945 574.00 0.01 0.16 4 Up 0.178939373926826 37252 1899.00 0.105 0.135 0.362570079384708 Up 0.0611874257033417 Ir56d ionotropic receptor 56d K05331|1|1e-08|61.6|tca:663613|chloride channel, invertebrate - - - 42787 773.00 33.75 23.505 -0.521919821631819 Down 0.595562012944129 CG13822 CG13822 K08059|1|4e-10|65.1|bta:615930|interferon, gamma-inducible protein 30 - - - 31696 2581.00 0.155 0.39 1.33120590847537 Up 0.172467309470347 Nek2 Nek2 K08857|1|0.0|1147|dme:Dmel_CG17256|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] - - - 32651 813.00 1.94 0.45 -2.10805974585745 Down 0.457007000396249 CG9672 CG9672 K01362|1|2e-31|135|dme:Dmel_CG2071| [EC:3.4.21.-];K09636|2|4e-21|101|mdo:100032186|transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-];K08668|3|5e-21|101|bta:506380|kallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117];K01312|4|6e-21|100|dpo:Dpse_GA11574|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway 43845 1749.00 0.115 0.135 0.231325546106456 Up 0.0521727644961036 CG11231 CG11231 - - - - 19836068 347.00 1.265 0.31 -2.02879726430743 Down 0.376997754589882 35087 908.66 2.48 2.055 -0.271201726705192 Down 0.171509708096685 CG15155 CG15155, isoform B - - GO:0016407//acetyltransferase activity - 32366 589.00 0.25 0.415 0.7311832415722 Up 0.129144102496368 CG13403 CG13403, isoform B - - - - 42632 2902.36 31.46 34.82 0.146397532235414 Up 0.308578787478537 lqfR liquid facets-Related, isoform D K12471|1|3e-32|141|xtr:448199|epsin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0001505//regulation of neurotransmitter levels;GO:0001505//regulation of neurotransmitter levels 31690 1968.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 Ir7b ionotropic receptor 7b - - - - 4379852 611.00 2.62 4.265 0.70297892978084 Up 0.402390701360454 CG34107 CG34107 - - - - 12798159 583.00 0.075 0.39 2.37851162325373 Up 0.222790912693171 CG43167 CG43167 - - - - 326126 1421.00 0.115 0.24 1.06140054466414 Up 0.117487782327302 CG31220 CG31220 K01362|1|7e-54|211|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|2e-46|186|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 319012 1172.00 3.315 2.955 -0.165850739935055 Down 0.144201558578787 CG31898 CG31898 - - - - 34964 2262.00 0.715 0.755 0.0785334025466893 Up 0.0531303658697662 c(2)M crossover suppressor on 2 of manheim - GO:0000794//condensed nuclear chromosome - GO:0007131//reciprocal meiotic recombination 246609 1060.00 0.55 0.57 0.0515303006400818 Up 0.0451063267732136 CG30429 CG30429 K04575|1|2e-12|73.6|spu:580872|amyotrophic lateral sclerosis 2 (juvenile) - - - 31678 6885.08 10.415 10.565 0.020629927894294 Up 0.0642253335094439 CHES-1-like checkpoint suppressor homologue, isoform D K09407|1|4e-49|198|tca:100141565|forkhead box protein N - - - 318139 2012.00 0.095 0.025 -1.92599941855622 Down 0.095099722625809 Mur11Da mucin related 11Da - - - - 35239 4586.05 26.57 26.53 -0.00217355226181082 Down 0.0434552899220711 CG10132 CG10132, isoform B K07972|1|1e-07|59.7|ame:551950|guanine nucleotide binding protein (G protein), beta, other;K01062|2|8e-06|53.9|bfo:BRAFLDRAFT_59218|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - GO:0016462//pyrophosphatase activity;GO:0032559 GO:0030908//protein splicing 32565 969.67 235.39 246.855 0.06861083476788 Up 0.201294412891296 CG9172 CG9172, isoform C K03940|1|4e-115|414|dme:Dmel_CG9172|NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0051536//iron-sulfur cluster binding;GO:0046914//transition metal ion binding;GO:0048037//cofactor binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0051536//iron-sulfur cluster binding;GO:0046914//transition metal ion binding;GO:0048037//cofactor binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0006979//response to oxidative stress;GO:0010257;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain;GO:0006979//response to oxidative stress;GO:0010257;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain 14462671 676.02 0.01 0.295 4.88264304936184 Up 0.269251089684322 50428 427.00 165.395 104.745 -0.65903424298929 Down 0.679764892352397 CG13779 Sem1 ortholog - - - - 41676 1204.00 5.025 6.15 0.291462814160311 Up 0.285629375247656 CG14367 CG14367 - - - - 33285 4498.56 7.035 8.355 0.248089404824655 Up 0.292035398230089 mtRNApol mitochondrial RNA polymerase, isoform B K10908|1|0.0|2534|dme:Dmel_CG4644|DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6] - GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0010467//gene expression 41254 1114.00 3.195 3.11 -0.0389013508163918 Down 0.0603288865407476 Sirt6 Sirt6 K11416|1|0.0|646|dme:Dmel_CG6284|mono-ADP-ribosyltransferase sirtuin 6 [EC:2.4.2.31] - GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0046914//transition metal ion binding;GO:0051287//NAD binding GO:0016458//gene silencing;GO:0010259//multicellular organismal aging;GO:0006464//cellular protein modification process 36364 2299.03 0.285 0.765 1.42449782852791 Up 0.255382380134725 dgt5 dim gamma-tubulin 5, isoform B - GO:0015630//microtubule cytoskeleton GO:0005488//binding GO:0007067//mitosis;GO:0008152//metabolic process 37034 2314.00 5.26 4.435 -0.246128694991238 Down 0.235338792761854 aft adrift K02427|1|7e-10|66.2|tad:TRIADDRAFT_62287|ribosomal RNA large subunit methyltransferase E [EC:2.1.1.-] - - - 43030 1621.00 52.935 52.81 -0.00341078942944192 Down 0.0456016378285563 CG31103 CG31103 K06258|1|8e-46|184|tca:662982|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 GO:0044464//cell part - GO:0006810//transport 12798513 1097.00 3.145 1.88 -0.742327355201652 Down 0.36735569937921 33905 2026.40 83.04 73.21 -0.181765719161186 Down 0.381455554087967 Sec61alpha Sec61 alpha subunit, isoform B K10956|1|0.0|940|dya:Dyak_GE18437|protein transport protein SEC61 subunit alpha GO:0031224//intrinsic to membrane;GO:0005783//endoplasmic reticulum GO:0008320//protein transmembrane transporter activity GO:0001700//embryonic development via the syncytial blastoderm;GO:0007033//vacuole organization;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006914//autophagy;GO:0006984//ER-nucleus signaling pathway 40976 681.00 0.875 0.01 -6.45121111183233 Down 0.471371021001189 CG11671 CG11671 - - - - 39270 2783.87 91.135 68.895 -0.403605936916649 Down 0.583113195086514 scyl scylla, isoform C K08270|1|3e-08|60.8|xtr:394782|DNA-damage-inducible transcript 4 GO:0044424//intracellular part - GO:0001700//embryonic development via the syncytial blastoderm;GO:0033554//cellular response to stress;GO:0009966//regulation of signal transduction;GO:0012501//programmed cell death;GO:0040008//regulation of growth 40441 2166.00 3.175 2.72 -0.223149940409189 Down 0.171509708096685 CG7458 CG7458 K08202|1|1e-68|261|isc:IscW_ISCW020957|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 36882 1429.00 0.265 0.01 -4.7279204545632 Down 0.2511557257958 CG15615 CG15615 - - - - 3346206 5298.00 11.435 14.06 0.298140228660863 Up 0.39747061154405 CG42313 CG42313, isoform B K06491|1|2e-18|95.5|hsa:4685|neural cell adhesion molecule;K06467|3|1e-17|93.2|cfa:476485|CD22 antigen GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane - GO:0006810//transport 19835573 2095.00 0.075 0.11 0.552541023028779 Up 0.0683529256373002 37849 288.00 1846.455 1764.685 -0.0653474206499553 Down 0.205752212389381 RpL39 ribosomal protein L39 K02924|1|3e-25|112|dgr:Dgri_GH21710|large subunit ribosomal protein L39e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 49427 1708.00 20.185 19.105 -0.079333329122999 Down 0.173986263373398 l(2)37Bb lethal (2) 37Bb - - GO:0003824//catalytic activity - 35505 3082.03 60.835 42.82 -0.506616787785529 Down 0.618115176330736 scaf scarface, isoform B K01312|1|1e-18|96.3|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09640|2|2e-16|89.0|bta:518647|transmembrane protease, serine 9 [EC:3.4.21.-];K01324|5|3e-16|88.2|hsa:3818|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 37276 1325.00 18.035 21.465 0.251186749660254 Up 0.392880729097873 CG16898 CG16898 - - - - 43714 715.00 0.115 0.25 1.12029423371771 Up 0.122308809932638 CG11333 CG11333 - - - - 31142 3419.00 2.785 2.93 0.0732233370822161 Up 0.0780610223220182 CG14803 CG14803, isoform B K13342|1|4e-13|77.8|dse:Dsec_GM18948|peroxin-5 - - - 318934 1086.00 212.5 113.85 -0.900328549775804 Down 0.721007792893937 CG31769 CG31769 - - - - 42319 1566.00 0.56 1.145 1.03184886603934 Up 0.267831197992339 CG18493 CG18493 K01285|1|6e-63|241|dme:Dmel_CG11626|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2];K09649|2|7e-50|198|mmu:54373|protease, serine, 16 (thymus) [EC:3.4.-.-] - GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 5740627 614.00 0.01 0.225 4.49185309632967 Up 0.222989037115308 14462524 1848.00 8.735 8.935 0.0326600261247309 Up 0.0763109232598072 19835943 605.00 0.07 0.155 1.14684138832927 Up 0.0982366926429798 42089 3557.20 38.535 35.48 -0.119163381320909 Down 0.267269845462951 lute lute, isoform D K10478|1|0.0|1078|dya:Dyak_GE10124|BTB/POZ domain-containing protein 3/6 - - - 19835273 885.00 0.835 0.865 0.0509239351626725 Up 0.0483423590014529 41560 3938.00 0.04 0.055 0.459431618637297 Up 0.0547483819838859 CG14395 CG14395, isoform J - - - - 246458 1997.28 13.49 7.61 -0.825921989444722 Down 0.598566900013208 NT5E-2 Ecto-5'-nucleotidase 2, isoform B K01081|1|0.0|1151|dme:Dmel_CG30104|5'-nucleotidase [EC:3.1.3.5] - GO:0016787//hydrolase activity;GO:0043169//cation binding;GO:0016787//hydrolase activity;GO:0043169//cation binding GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 35374 3471.00 3.94 3.795 -0.0540957440409102 Down 0.0745938449346189 CG12050 CG12050 - - - - 35828 2044.51 40.69 50.295 0.30574070344123 Up 0.503599260335491 Mal-A5 maltase A5, isoform C K01187|1|0.0|724|dme:Dmel_CG8693|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding;GO:0043167//ion binding GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 39348 2148.00 0.405 0.68 0.747612838365715 Up 0.170023774930656 CG5718 CG5718 K00234|1|0.0|1285|dme:Dmel_CG5718|succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] - GO:0030554//adenyl nucleotide binding;GO:0000104//succinate dehydrogenase activity GO:0009060//aerobic respiration 41650 1122.00 105.835 87.715 -0.27092132877073 Down 0.488772949412231 CG9796 CG9796 K08059|1|6e-21|101|dre:336503|interferon, gamma-inducible protein 30 - - - 14462872 995.00 0.605 0.49 -0.304153393159386 Down 0.0972460705322943 33966 1813.00 11.19 7.995 -0.485040097496062 Down 0.47741381587637 nop5 nop5 K12844|1|6e-30|132|dwi:Dwil_GK20402|U4/U6 small nuclear ribonucleoprotein PRP31 - - GO:0042254//ribosome biogenesis 31284 1570.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG14420 CG14420 - - - - 37563 1440.00 13.435 17.725 0.399789306113713 Up 0.488112534671774 mRpS29 mitochondrial ribosomal protein S29 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0012501//programmed cell death 43263 995.00 24.145 11.305 -1.09476347142113 Down 0.682538634262317 CG17189 CG17189 - - - - 42925 1514.00 17.985 14.925 -0.269063227983212 Down 0.396446968696341 CG6607 CG6607 K10352|1|3e-12|73.2|rno:29605|myosin heavy chain - - - 43814 26508.87 23.535 17.22 -0.45072271029241 Down 0.541969356756043 bt bent, isoform J K12567|1|0.0|2002|cfa:478819|titin [EC:2.7.11.1] GO:0031674//I band GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005198//structural molecule activity GO:0006464//cellular protein modification process;GO:0009888//tissue development 33195 2220.76 11.285 12.105 0.101196660807101 Up 0.176132611279884 CG17078 CG17078, isoform E - - - - 39484 978.65 807.335 812.695 0.00954658078646174 Up 0.070829480914014 RpS4 ribosomal protein S4, isoform C K02987|1|5e-149|526|dsi:Dsim_GD14426|small subunit ribosomal protein S4e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 31526 1995.72 7.28 7.905 0.118827012159675 Up 0.170056795667679 CG12728 CG12728, isoform B - - - - 37748 1230.00 10.22 9.665 -0.0805535587263856 Down 0.140106987187954 angel angel K12603|1|4e-09|62.8|spu:580732|CCR4-NOT transcription complex subunit 6 [EC:3.1.-.-] - - - 19834900 822.00 3.93 4.37 0.153103967241992 Up 0.154371945581825 36907 1464.00 0.845 1.375 0.702408372129838 Up 0.234579315810329 ste24b ste24b prenyl protease type I K06013|1|8e-78|291|dwi:Dwil_GK19569|STE24 endopeptidase [EC:3.4.24.84] - - - 30990 630.65 10.355 12.165 0.232408766717917 Up 0.320169066173557 CG3176 CG3176, isoform D - - - - 36376 2334.00 5.825 6.65 0.19109629084691 Up 0.221371021001189 CG8569 CG8569 - - GO:0046914//transition metal ion binding - 3772418 299.00 11.185 5.61 -0.995492580450326 Down 0.612006339981508 41361 3306.22 0.595 0.79 0.40896298486916 Up 0.128384625544842 KP78b KP78b, isoform B K08286|1|0.0|1221|dme:Dmel_CG6715|protein-serine/threonine kinase [EC:2.7.11.-];K08798|5|0.0|1028|dsi:Dsim_GD20665|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 12798374 2901.00 9.565 10.095 0.0778040369853608 Up 0.138125742966583 12798466 250.40 4.575 17.175 1.90846645053406 Up 0.722724871219126 CG43236 CG43236, isoform B - - - - 41164 845.25 73.76 93.605 0.34374693902587 Up 0.548606524897636 CG9427 CG9427, isoform B K08059|1|2e-15|82.8|dre:336503|interferon, gamma-inducible protein 30 - - - 39202 2511.00 6.525 6.345 -0.0403577376161408 Down 0.0776317527407212 hay haywire, isoform B K10843|1|0.0|1472|dme:Dmel_CG8019|DNA excision repair protein ERCC-3 [EC:3.6.1.-] GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0003702//RNA polymerase II transcription factor activity;GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0003702//RNA polymerase II transcription factor activity GO:0006281//DNA repair;GO:0006352//DNA-dependent transcription, initiation;GO:0009416//response to light stimulus;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006281//DNA repair;GO:0006352//DNA-dependent transcription, initiation;GO:0009416//response to light stimulus;GO:0000380//alternative mRNA splicing, via spliceosome 31121 6017.70 33.25 46.095 0.471255927038204 Up 0.592028794082684 CG32809 CG32809, isoform M - - - - 42883 1516.00 3.05 2.84 -0.102918312945567 Down 0.0966847180029058 CG13609 CG13609 - - - GO:0048731 32887 1888.00 0.915 1.975 1.11000900478042 Up 0.360091137234183 CG7349 CG7349, isoform C K00235|1|8e-177|620|dme:Dmel_CG7349|succinate dehydrogenase (ubiquinone) iron-sulfur protein [EC:1.3.5.1] GO:0015630//microtubule cytoskeleton;GO:0005746//mitochondrial respiratory chain GO:0051540;GO:0000104//succinate dehydrogenase activity GO:0022904//respiratory electron transport chain;GO:0009060//aerobic respiration 39952 834.00 1.2 0.775 -0.630766190334281 Down 0.205322942808083 qjt quijote, isoform B - - - - 44843 4956.11 7.18 6.565 -0.129188832930165 Down 0.173986263373398 nkd naked cuticle, isoform C K03213|1|0.0|1365|dme:Dmel_CG11614|naked cuticle GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0001708//cell fate specification 31052 2214.00 6.91 6.115 -0.176333211860872 Down 0.214502707700436 CDC45L CDC45L K06628|1|0.0|1010|dme:Dmel_CG3658|cell division control protein 45 - - - 36438 997.00 55.095 53.44 -0.0440013889787617 Down 0.129705455025756 CG3955 CG3955 - - - - 31375 1643.00 0.37 0.98 1.40525647848626 Up 0.288006868313301 CG12693 CG12693 - - - - 36381 2647.00 20.155 16.66 -0.274749382485532 Down 0.40836745476159 ClC-b chloride channel-b K05331|1|0.0|1555|dme:Dmel_CG8594|chloride channel, invertebrate GO:0031224//intrinsic to membrane GO:0005254//chloride channel activity GO:0015698//inorganic anion transport 39649 3284.00 0.265 0.27 0.0269670476002694 Up 0.0416391493858143 CG13457 CG13457, isoform B - - - - 43535 3374.58 55.845 63.05 0.175068253642913 Up 0.372308809932638 CG31038 CG31038, isoform H - - - - 35043 516.00 15.605 21.925 0.490568485412885 Up 0.552866199973583 Rpb11 Rpb11 K03008|1|3e-62|236|dvi:Dvir_GJ16235|DNA-directed RNA polymerase II subunit J GO:0016591//DNA-directed RNA polymerase II, holoenzyme GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0016301//kinase activity;GO:0019904//protein domain specific binding GO:0006396//RNA processing;GO:0006354//DNA-dependent transcription, elongation;GO:0006352//DNA-dependent transcription, initiation 39306 1275.00 7.005 6.465 -0.115734680620564 Down 0.158862765816933 PCID2 PCI domain-containing protein 2 K03033|1|3e-06|53.1|smm:Smp_085310.2|26S proteasome regulatory subunit N3 GO:0030529//ribonucleoprotein complex GO:0004623//phospholipase A2 activity - 31586 1709.00 4.79 5.48 0.194150237224347 Up 0.203407740060758 CG3342 CG3342 - - - - 36156 4586.13 8.855 9.5 0.101435206466396 Up 0.160777968564258 CG30020 CG30020, isoform C K09228|1|2e-20|102|rno:499056|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 33072 3971.00 0.14 0.15 0.0995356735509147 Up 0.0433232069739797 Npc1b Niemann-Pick type C-1b K12385|1|0.0|2451|dme:Dmel_CG12092|Niemann-Pick C1 protein GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0015918//sterol transport 39279 1395.00 0.82 0.52 -0.657112286476991 Down 0.170519085985999 CG12289 CG12289 K00846|1|0.0|737|dme:Dmel_CG12289|ketohexokinase [EC:2.7.1.3] - - - 35672 2709.07 9.805 9.38 -0.0639297076767725 Down 0.11689340906089 CG11141 CG11141, isoform C - - GO:0016872//intramolecular lyase activity;GO:0016872//intramolecular lyase activity GO:0006020//inositol metabolic process;GO:0006644//phospholipid metabolic process;GO:0006020//inositol metabolic process;GO:0006644//phospholipid metabolic process 41569 2622.25 52.45 46.67 -0.168447305500486 Down 0.353090740985339 Past1 putative achaete scute target 1, isoform B K12483|1|0.0|1090|dsi:Dsim_GD18857|EH domain-containing protein 1 - - - 39459 2838.58 20.525 25.13 0.292028449215488 Up 0.444227975168406 CG10948 CG10948, isoform D - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 4379912 796.00 5.75 5.92 0.0420352197972122 Up 0.0758816536785101 CG34116 CG34116 - - GO:0003676//nucleic acid binding - 41717 2683.00 1.15 1.135 -0.0189415636534601 Down 0.0413749834896315 Kif19A kinesin family member 19A ortholog K10401|1|0.0|1257|dme:Dmel_CG9913|kinesin family member 18/19 - - - 36650 883.28 147.615 112.5 -0.391914327856218 Down 0.587967243428873 CG10205 CG10205, isoform B - - - - 3346221 548.00 2 0.845 -1.24297675349254 Down 0.381752740721173 lectin-37Db lectin-37Db, isoform B K06560|1|1e-09|62.4|cin:100186027|mannose receptor, C type;K10065|2|1e-08|59.3|gga:420281|collectin sub-family member 10 - - - 33994 2102.00 2.5 1.575 -0.666576266274808 Down 0.306036190727777 Pvf2 PDGF- and VEGF-related factor 2 - GO:0044464//cell part GO:0005126//cytokine receptor binding GO:0007431//salivary gland development;GO:0016477//cell migration;GO:0002376//immune system process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 43391 3529.05 114.44 83.535 -0.454138704305015 Down 0.613393210936468 CG9990 CG9990, isoform G K05648|1|2e-26|121|xtr:100216156|ATP-binding cassette, subfamily A (ABC1), member 5 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 38277 1183.00 0.035 0.26 2.89308479608349 Up 0.187491744815744 CG15820 CG15820 K01175|1|4e-29|129|mmu:68607| [EC:3.1.-.-];K13699|2|2e-07|56.6|nve:NEMVE_v1g125604|abhydrolase domain-containing protein 5 [EC:2.3.1.51];K13700|3|2e-07|56.6|dre:799085|abhydrolase domain-containing protein 6 [EC:3.1.1.23] - - - 31100 753.00 13.445 14.895 0.147758368376657 Up 0.254094571390833 CG14778 CG14778 K13348|1|4e-58|224|dmo:Dmoj_GI16042|protein Mpv17 - - - 35941 2020.84 46.505 45.715 -0.0247182165037436 Down 0.0871087042662792 CG8026 CG8026, isoform D K13354|1|4e-111|402|nvi:100116581|solute carrier family 25 member 17 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity GO:0046907//intracellular transport;GO:0006865//amino acid transport;GO:0046907//intracellular transport;GO:0006865//amino acid transport;GO:0046907//intracellular transport;GO:0006865//amino acid transport 8674072 823.32 934.67 795.085 -0.233347986073001 Down 0.467045304451195 CG42502 CG42502, isoform C - - - - 14462455 985.00 0.125 0.23 0.879705766282288 Up 0.103255844670453 CG44037 CG44037 - - - - 3772307 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 3355040 7608.75 29.355 32.37 0.141051108861213 Up 0.292761854444591 CG17514 CG17514, isoform G K11886|1|2e-12|76.6|oaa:100081437|proteasome component ECM29 - GO:0005488//binding - 8674099 2268.00 0.1 0.095 -0.0740005814437769 Down 0.042365605600317 CG41056 CG41056 - - - - 12798517 310.00 2.09 5.27 1.33430001955633 Up 0.559239202218993 CG43094 CG43094 - - - - 35908 3757.62 1.735 1.635 -0.0856450270801782 Down 0.0702351076476027 CG8170 CG8170, isoform B K01312|1|1e-46|189|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01316|2|4e-41|171|tgu:100220466|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K09626|3|5e-41|170|bta:510394|protease, serine, 22 [EC:3.4.21.-] GO:0044464//cell part;GO:0044464//cell part GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity;GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 39845 995.00 88.555 57.605 -0.620379726671037 Down 0.660976092986395 Rpn12 regulatory particle non-ATPase 12 K03031|1|5e-134|477|dme:Dmel_CG4157|26S proteasome regulatory subunit N12 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0007052//mitotic spindle organization 19836241 698.00 0.06 0.13 1.11547721741994 Up 0.0918306696605468 40396 887.87 86.615 98.08 0.179342086274628 Up 0.384625544842161 CG32441 CG32441, isoform D - - - - 40232 2324.00 0.485 0.645 0.411314413236127 Up 0.115935807687228 polo polo, isoform B K06631|1|0.0|1147|dse:Dsec_GM22270|polo-like kinase 1 [EC:2.7.11.21] GO:0005815//microtubule organizing center;GO:0000777//condensed chromosome kinetochore;GO:0005815//microtubule organizing center;GO:0000777//condensed chromosome kinetochore GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559 GO:0033036;GO:0006909//phagocytosis;GO:0007097//nuclear migration;GO:0000741//karyogamy;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0007056//spindle assembly involved in female meiosis;GO:0006464//cellular protein modification process;GO:0007140//male meiosis;GO:0000087//M phase of mitotic cell cycle;GO:0033036;GO:0006909//phagocytosis;GO:0007097//nuclear migration;GO:0000741//karyogamy;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0007056//spindle assembly involved in female meiosis;GO:0006464//cellular protein modification process;GO:0007140//male meiosis;GO:0000087//M phase of mitotic cell cycle 19835867 697.00 28.565 31.555 0.143620093468977 Up 0.292596750759477 32382 1367.00 23.18 27.74 0.259087221317131 Up 0.421608770307753 CG13404 CG13404 - - - - 5740817 567.00 0.145 0.01 -3.85798099512757 Down 0.168967111345925 CG34283 CG34283 K02728|1|1e-11|68.2|ame:413757|20S proteasome subunit alpha 3 [EC:3.4.25.1] - - - 43379 14238.00 0.08 0.305 1.93073733756289 Up 0.172896579051644 Dhc98D dynein heavy chain at 89D, isoform D K01509|1|0.0|8286|dpo:Dpse_GA14931|adenosinetriphosphatase [EC:3.6.1.3];K10408|4|0.0|2146|rno:303242|dynein heavy chain, axonemal GO:0030286//dynein complex;GO:0030286//dynein complex GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0032559;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 39086 2425.45 62.405 62.11 -0.00683605723589278 Down 0.0639611676132611 CG3967 CG3967, isoform F - - - - 31188 1652.63 0.395 3.47 3.13501110440116 Up 0.614813102628451 Cyp4d1 cytochrome P450-4d1, isoform B K00517|1|0.0|761|dme:Dmel_CG3656| [EC:1.14.-.-] - - - 38378 976.00 204.635 209.92 0.0367867057527186 Up 0.136342623167349 CG12079 NADH dehydrogenase (ubiquinone) Fe-S protein 3 K03936|1|5e-137|486|dme:Dmel_CG12079|NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0006091//generation of precursor metabolites and energy 41450 1590.00 74.965 64.28 -0.221847251767413 Down 0.428741249504689 Tango9 transport and golgi organization 9 - GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity GO:0006810//transport 32335 733.78 181.75 173.385 -0.0679762715924568 Down 0.199214106458856 CG11151 CG11151, isoform B K12405|1|1e-42|172|aag:AaeL_AAEL007023|3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase [EC:1.1.1.35 4.2.1.107] GO:0044444//cytoplasmic part GO:0003824//catalytic activity;GO:0005496//steroid binding GO:0008152//metabolic process 43430 1076.00 64.215 65.64 0.031664902595637 Up 0.109397701756703 CG11841 CG11841 K09641|1|1e-24|114|mmu:231382|transmembrane protease, serine 11D [EC:3.4.21.-];K01324|2|3e-24|112|gga:422723|plasma kallikrein [EC:3.4.21.34];K01312|4|7e-24|111|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19836018 458.00 0.105 0.21 1 Up 0.107350416061286 37385 712.00 252.675 278.25 0.139098758386408 Up 0.337240787214371 CG9350 CG9350 K03956|1|5e-78|290|dme:Dmel_CG9350|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11 [EC:1.6.5.3] - - - 43875 4723.61 1.62 2.37 0.548893246013634 Up 0.270109628846916 Ret Ret oncogene, isoform C K05126|1|0.0|2424|dme:Dmel_CG14396|proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1] GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0016337//cell-cell adhesion;GO:0006464//cellular protein modification process;GO:0016337//cell-cell adhesion;GO:0006464//cellular protein modification process;GO:0016337//cell-cell adhesion;GO:0006464//cellular protein modification process 43266 2302.00 8.16 8.06 -0.0177893134435285 Down 0.0586448289525822 CG5815 CG5815, isoform C - - - - 34062 2834.00 10.185 10.595 0.0569376074062818 Up 0.115044247787611 CG7154 CG7154 K11723|1|0.0|1272|dme:Dmel_CG7154|bromodomain-containing protein 7/9 GO:0043231//intracellular membrane-bounded organelle - - 37200 1634.86 47.04 54.375 0.209055435674451 Up 0.405725795799762 CG15111 CG15111, isoform B K13704|1|6e-62|238|mmu:76192|abhydrolase domain-containing protein 12 [EC:3.1.1.23] - - - 38669 2190.91 13.265 13.13 -0.0147577593358089 Down 0.0570268128384626 Bj1 regulator of chromosome condensation 1 ortholog, isoform C K11493|1|0.0|939|dme:Dmel_CG10480|regulator of chromosome condensation GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0051960//regulation of nervous system development;GO:0000070//mitotic sister chromatid segregation;GO:0032386//regulation of intracellular transport;GO:0051960//regulation of nervous system development;GO:0000070//mitotic sister chromatid segregation;GO:0032386//regulation of intracellular transport;GO:0051960//regulation of nervous system development;GO:0000070//mitotic sister chromatid segregation;GO:0032386//regulation of intracellular transport 42008 1111.00 0.555 0.35 -0.66513284940514 Down 0.140668339717342 decay death executioner caspase related to Apopain/Yama K04489|1|1e-45|184|aga:AgaP_AGAP000830|caspase invertebrate, apoptosis-related cysteine protease [EC:3.4.22.-] - - - 3885596 1084.00 1.69 0.53 -1.67295898171898 Down 0.399451855765421 CG34038 CG34038, isoform C - - - - 10178948 386.00 0.335 0.395 0.23769155771933 Up 0.0707634394399683 CG42787 CG42787 - - - - 19835294 658.00 0.245 0.085 -1.52724700286487 Down 0.14109760929864 34067 3842.16 28 27.425 -0.0299352065417738 Down 0.0990291903315282 cdc14 cdc14, isoform E K06639|1|0.0|1427|dsi:Dsim_GD22466|cell division cycle 14 [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 19835863 344.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 35681 1711.00 15.16 17.77 0.229173927857586 Up 0.357449478272355 CG12736 CG12736 K02358|1|0.0|875|dme:Dmel_CG12736|elongation factor EF-Tu [EC:3.6.5.3] GO:0043231//intracellular membrane-bounded organelle GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006412//translation 41997 1838.00 12.625 10.64 -0.24678523702533 Down 0.338528595958262 CG14883 CG14883 - - - - 32678 1094.99 12.65 16.21 0.357746705935869 Up 0.456049399022586 Rcp receptor component protein, isoform C - - GO:0034062//RNA polymerase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0006412//translation 19835316 1401.00 0.035 0.035 0 - 0.0382380134724607 36431 6140.66 3.025 2.875 -0.0733731863302194 Down 0.0780610223220182 Psc posterior sex combs, isoform C K11459|1|0.0|2093|dme:Dmel_CG3886|polycomb group RING finger protein 4 GO:0031519//PcG protein complex;GO:0005720//nuclear heterochromatin GO:0046872//metal ion binding GO:0016568//chromatin modification;GO:0016458//gene silencing;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0006935//chemotaxis 38769 4449.24 34.285 26.81 -0.354806302883304 Down 0.51436402060494 mp multiplexin, isoform U K08135|1|4e-50|200|hsa:1306|collagen, type XV, alpha GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix - GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance;GO:0007411//axon guidance 19835214 1523.00 0.34 0.3 -0.180572245641821 Down 0.0605270109628847 36194 2191.95 12.54 11.425 -0.134343182856607 Down 0.219422797516841 Cpr47Ef cuticular protein 47Ef, isoform D - - GO:0042302//structural constituent of cuticle;GO:0042302//structural constituent of cuticle - 43352 3673.13 11 13.865 0.333944092627457 Up 0.421014397041342 CG5514 CG5514, isoform E - - - - 38186 8335.79 47.595 54.665 0.199807401757443 Up 0.394498745211993 CG13917 CG13917, isoform C K10480|1|3e-32|142|ptr:469383|BTB/POZ domain-containing protein 8 - GO:0005488//binding;GO:0005488//binding - 43213 6138.00 14.735 19.59 0.410870337143587 Up 0.503401135913354 beat-VII beat-VII - GO:0044464//cell part - - 31157 3682.30 19.84 22.09 0.1549813929684 Up 0.28602562409193 Ocrl oculocerebrorenal syndrome of lowe ortholog, isoform B K01099|1|5e-160|565|aag:AaeL_AAEL003143|phosphatidylinositol-bisphosphatase [EC:3.1.3.36] - - - 34806 2222.00 5.145 0.785 -2.71240651800234 Down 0.652027473253203 Ance-2 Ance-2 K01283|1|0.0|1246|dme:Dmel_CG16869|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0044464//cell part GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 36239 2296.51 2.245 2.595 0.209019093616734 Up 0.147635715229164 inv invected, isoform E K09319|1|1e-48|195|dpo:Dpse_GA21479|homeobox protein engrailed - GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding GO:0048731;GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0009952//anterior/posterior pattern specification;GO:0048731;GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0009952//anterior/posterior pattern specification;GO:0048731;GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0009952//anterior/posterior pattern specification 35324 634.00 8.32 9.32 0.163746426513188 Up 0.226918504821028 CG2611 CG2611 - - - - 3772681 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 35664 2122.00 5.48 5.25 -0.0618584704070419 Down 0.09047681944261 CG11123 CG11123 - - GO:0003676//nucleic acid binding - 41972 1287.00 0.975 1.395 0.516790998079577 Up 0.197530048870691 Mst89B Mst89B - - - - 44183 1883.00 85.31 66.91 -0.350493019288661 Down 0.552502971866332 ScpX sterol carrier protein X-related thiolase K08764|1|0.0|1091|dme:Dmel_CG17320|sterol carrier protein 2 [EC:2.3.1.176] GO:0042579//microbody GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0005319//lipid transporter activity;GO:0005496//steroid binding GO:0006869//lipid transport 19835835 823.00 3.57 2.2 -0.69842055050444 Down 0.373431514991415 41152 1486.42 14.555 12.705 -0.196118464069411 Down 0.3072249372606 CG9393 CG9393, isoform B - GO:0031966//mitochondrial membrane - GO:0006605//protein targeting 38532 1378.69 27.22 30.725 0.174745943756029 Up 0.331759344868577 CG32250 CG32250, isoform B K13354|1|9e-166|583|dme:Dmel_CG32250|solute carrier family 25 member 17 GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport 48785 1886.37 5.925 6.11 0.0443572260331081 Up 0.0795799762250693 wek weckle, isoform B K09228|1|6e-35|149|ptr:455898|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding GO:0010468//regulation of gene expression;GO:0007310//oocyte dorsal/ventral axis specification;GO:0007166//cell surface receptor signaling pathway 32268 1936.00 16.4 15.285 -0.101579262618476 Down 0.194260995905429 Bap60 brahma associated protein 60kD K11650|1|0.0|862|dsi:Dsim_GD15903|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 42143 1706.00 2.935 3.755 0.35545240440422 Up 0.260995905428609 CG17802 CG17802 K09228|1|1e-26|121|hsa:7711|KRAB domain-containing zinc finger protein - - - 19835778 1107.00 4.355 4.43 0.0246339799561534 Up 0.0542200501915203 5740743 853.00 0.095 0.16 0.752072486556414 Up 0.0813630960243033 CG34436 CG34436 K01344|1|2e-16|85.9|mdo:100026692|protein C (activated) [EC:3.4.21.69];K01323|4|6e-14|77.8|mmu:109821|coagulation factor XI [EC:3.4.21.27];K01314|5|2e-13|75.9|rno:29243|coagulation factor X [EC:3.4.21.6] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42703 6643.75 54.755 60.65 0.147516933675955 Up 0.328457271166292 CG7029 CG7029, isoform I - - - - 31593 3700.82 15.595 17.3 0.149688485149935 Up 0.266576409985471 Pat1 protein interacting with APP tail-1, isoform C K10407|1|1e-05|53.1|cbr:CBG09366|kinesin light chain - - - 42402 5890.95 9.87 11.88 0.267412846344368 Up 0.350283978338397 CG34139 neuroligin 4, isoform E K01044|1|0.0|1868|dme:Dmel_CG34139|carboxylesterase [EC:3.1.1.1];K07378|2|0.0|1341|der:Dere_GG23789|neuroligin - GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding - 19836076 323.00 0.15 0.01 -3.90689059560852 Down 0.171410645885616 34371 530.99 106.41 99.045 -0.103477684322475 Down 0.254127592127856 CG18619 CG18619, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 37551 1959.00 8.865 11.995 0.436240621394746 Up 0.464370624752344 T3dh type III alcohol dehydrogenase K11173|1|0.0|899|dme:Dmel_CG3425|hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24] GO:0043231//intracellular membrane-bounded organelle GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0043169//cation binding GO:0006818//hydrogen transport;GO:0008152//metabolic process 318965 950.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 CG31827 CG31827 K01312|1|3e-28|125|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09628|2|5e-27|121|xtr:595077|protease, serine 27 [EC:3.4.21.-];K09636|3|1e-26|120|dre:569688|transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-];K01324|4|3e-25|115|gga:422723|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835242 509.00 0.085 0.095 0.160464672193246 Up 0.045238409721305 33659 3203.46 33.51 28.1 -0.254021556096183 Down 0.425604279487518 ine inebriated, isoform F K05046|1|2e-134|480|mmu:14412|solute carrier family 6 (neurotransmitter transporter, GABA) member 13;K05045|2|3e-134|479|mdo:100016965|solute carrier family 6 (neurotransmitter transporter, betaine/GABA) member 12;K05041|3|1e-133|478|dre:567544|solute carrier family 6 (neurotransmitter transporter, creatine) member 8 GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity GO:0006810//transport;GO:0080134//regulation of response to stress;GO:0007154//cell communication;GO:0042065;GO:0006810//transport;GO:0080134//regulation of response to stress;GO:0007154//cell communication;GO:0042065;GO:0006810//transport;GO:0080134//regulation of response to stress;GO:0007154//cell communication;GO:0042065;GO:0006810//transport;GO:0080134//regulation of response to stress;GO:0007154//cell communication;GO:0042065;GO:0006810//transport;GO:0080134//regulation of response to stress;GO:0007154//cell communication;GO:0042065 35143 1566.00 0.265 0.355 0.421826664941483 Up 0.0914674415532955 CG31752 CG31752 - - - - 42440 1463.57 6.49 5.415 -0.261257140390812 Down 0.270571919165236 CG4159 CG4159, isoform B K06173|1|0.0|763|dme:Dmel_CG4159|tRNA pseudouridine synthase A [EC:5.4.99.12] - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0009451//RNA modification;GO:0006399//tRNA metabolic process;GO:0009451//RNA modification;GO:0006399//tRNA metabolic process 246650 1577.00 12.01 10.48 -0.196597434168184 Down 0.287874785365209 CG30493 CG30493 - - - GO:0006743//ubiquinone metabolic process 33370 4294.00 4.795 6.695 0.48155324030618 Up 0.399749042398626 CG15356 CG15356 - - GO:0016769//transferase activity, transferring nitrogenous groups;GO:0005488//binding GO:0008152//metabolic process 19836107 1920.00 0.365 0.58 0.668156436247555 Up 0.143904371945582 3772192 192.00 0.995 0.205 -2.27907261592556 Down 0.349788667283054 40707 1595.60 7.5 8.755 0.223216583050314 Up 0.276053361511029 CG2100 CG2100, isoform B K00974|1|0.0|965|dme:Dmel_CG2100|tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.25 2.7.7.21 3.1.3.- 3.1.4.-] - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0003676//nucleic acid binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0003676//nucleic acid binding GO:0010467//gene expression;GO:0010467//gene expression 43731 1060.00 52.95 61.885 0.224959079857478 Up 0.422863558314622 CG11550 CG11550 K10693|1|1e-24|114|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0044464//cell part - GO:0051234//establishment of localization 38912 2119.00 15.445 16.71 0.11357186243355 Up 0.212125214634791 ERR estrogen-related receptor, isoform B K08703|1|0.0|766|dme:Dmel_CG7404|estrogen-related receptor ERR GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009792//embryo development ending in birth or egg hatching;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 32503 3370.00 0.015 0.105 2.8073549220576 Up 0.120030379078061 CG15599 CG15599 - - - - 31722 9422.64 16.905 20.72 0.293573986793176 Up 0.428807290978735 fs(1)h female sterile (1) homeotic, isoform I K11721|1|6e-76|286|ame:551826|bromodomain-containing protein 3 - GO:0003676//nucleic acid binding;GO:0016301//kinase activity GO:0009880//embryonic pattern specification;GO:0032583 3346162 7177.74 19.715 23.61 0.260104331120826 Up 0.41021661603487 mun glial cell line-derived neurotrophic family receptor-like, isoform N - - GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0009437//carnitine metabolic process 31212 2010.37 22.795 26.9 0.238888763579221 Up 0.399815083872672 l(1)G0144 tempura, isoform B K05955|1|2e-10|68.2|bmy:Bm1_24725|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59];K05956|3|4e-10|67.0|tad:TRIADDRAFT_23729|geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] - - - 37104 1495.00 21.965 18.355 -0.259033384993214 Down 0.404272883370757 Idgf5 imaginal disc growth factor 5 K01183|1|4e-35|149|dme:Dmel_CG2989|chitinase [EC:3.2.1.14] - - - 43077 2091.00 7.255 6.605 -0.135417052819917 Down 0.181481970677586 Vps33B vacuolar protein sorting 33B - - - GO:0048278//vesicle docking 34436 3176.16 4.775 5.805 0.281795333942455 Up 0.271529520538898 CG5322 CG5322, isoform B K12311|1|0.0|1935|dsi:Dsim_GD22254|lysosomal alpha-mannosidase [EC:3.2.1.24] GO:0000323//lytic vacuole GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0019318//hexose metabolic process 43052 1358.00 12.77 4.72 -1.43589976034088 Down 0.671740853255845 CG10514 CG10514 - - - - 19835625 6301.00 0.01 0.02 1 Up 0.0497292299564126 32790 2747.23 2.98 3.325 0.15804200992639 Up 0.138059701492537 RhoGAP16F Rho GTPase activating protein at 16F, isoform F K08878|1|1e-11|72.4|mdo:100011712|breakpoint cluster region protein [EC:2.7.11.1] GO:0044464//cell part;GO:0044464//cell part - GO:0023060;GO:0023060 35901 1203.00 91.285 115.76 0.342687106605366 Up 0.55352661471404 CG8216 CG8216 - - - GO:0010468//regulation of gene expression 42048 2558.00 8.745 9.665 0.144311348289583 Up 0.209813763043191 CG16941 CG16941 K12825|1|0.0|1244|dme:Dmel_CG16941|splicing factor 3A subunit 1 - - - 19835258 411.00 0.855 1.89 1.14438990933518 Up 0.358274996697926 - CG45676 - - - - 36889 4972.31 23.74 26.62 0.165190636269985 Up 0.32112666754722 Psi P-element somatic inhibitor, isoform C K13210|1|0.0|664|dme:Dmel_CG8912|far upstream element-binding protein - - - 5740866 307.00 1.175 1.04 -0.176077228423908 Down 0.0926231673490952 CG34301 CG34301 - - - - 31470 3442.13 2.57 2.8 0.123658467751088 Up 0.104807819310527 Vsx1 visual system homeobox 1 ortholog, isoform B K09336|1|2e-49|197|dpe:Dper_GL16530|visual system homeobox protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0032501//multicellular organismal process 31920 735.00 118.21 128.755 0.123276372429202 Up 0.294313829084665 CG1468 CG1468 - - - - 246419 1088.00 2.805 2.885 0.0405705480366897 Up 0.0603288865407476 CG30053 CG30053 - - - - 19835152 1487.00 0.105 0.04 -1.39231742277876 Down 0.0864152687887994 36411 3796.00 9.83 11.24 0.193378713880345 Up 0.275161801611412 sca scabrous, isoform B K10104|1|4e-34|147|bfo:BRAFLDRAFT_252169|ficolin;K05467|3|2e-33|145|bta:617915|angiopoietin 4;K06252|4|4e-33|144|bfo:BRAFLDRAFT_124749|tenascin GO:0005615//extracellular space;GO:0005615//extracellular space GO:0060089;GO:0005515//protein binding;GO:0060089;GO:0005515//protein binding GO:0023060;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0007143//female meiosis;GO:0007389//pattern specification process;GO:0023060;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0007143//female meiosis;GO:0007389//pattern specification process 38390 587.00 10.46 12.635 0.272542812697834 Up 0.359034473649452 CG14966 CG14966 K09131|1|3e-71|266|dme:Dmel_CG14966|hypothetical protein - - - 34992 2080.71 12.875 14.98 0.218465191500808 Up 0.331164971602166 her hermaphrodite, isoform B K09228|1|3e-11|70.5|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0018993//somatic sex determination 19836035 1680.00 35.56 34.205 -0.0560480941455446 Down 0.158796724342887 34283 13330.00 19.16 21.525 0.167915676548026 Up 0.307125875049531 CG15828 apolipoprotein lipid transfer particle K03900|1|7e-07|58.9|gga:419031|von Willebrand factor;K13908|3|4e-06|56.6|rno:309114|mucin-5B GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0022892 GO:0006810//transport 8673980 357.26 91.87 67.935 -0.43543878857484 Down 0.603288865407476 Sfp60F seminal fluid protein 60F, isoform B - - - - 43599 386.00 7.25 7.405 0.0305187403865507 Up 0.06927750627394 CecC cecropin C - GO:0044421//extracellular region part - GO:0042742//defense response to bacterium 19835685 1112.00 0.04 0.355 3.14974711950468 Up 0.234645357284375 37130 2352.12 2.06 2.155 0.0650435319058799 Up 0.0677255316338661 CG10924 CG10924, isoform B K01596|1|0.0|1243|dsi:Dsim_GD11391|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] - - - 38029 1527.00 17.68 15.33 -0.205760577732654 Down 0.335457667415137 NitFhit nitrilase and fragile histidine triad fusion protein K01506|1|3e-74|279|cfa:478977| [EC:3.5.-.-] - GO:0016815//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles;GO:0005488//binding;GO:0004551//nucleotide diphosphatase activity GO:0034641//cellular nitrogen compound metabolic process 50320 4370.24 48.515 61.14 0.333685679567476 Up 0.528430854576674 dpr12 dpr12, isoform E K06762|1|7e-08|60.1|dre:571349|contactin 4;K06774|2|4e-07|57.8|xla:444598|neurotrimin;K06764|3|8e-07|56.6|cfa:484686|contactin 6;K04910|4|1e-06|56.2|spu:578213|potassium voltage-gated channel Eag-related subfamily H member 7;K06550|5|1e-06|56.2|mdo:100028028|L1 cell adhesion molecule - - - 5740777 1942.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 35837 1649.00 23.87 16.93 -0.495616593186135 Down 0.562739400343416 Cyp6a13 Cyp6a13 K00517|1|0.0|967|dme:Dmel_CG2397| [EC:1.14.-.-];K07424|2|0.0|936|dse:Dsec_GM21045|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 43779 1504.00 53.03 31.04 -0.772680190953618 Down 0.677651565182935 yellow-h yellow-h - - - - 35808 935.00 1.455 2.36 0.697767706453558 Up 0.308182538634262 CG11635 CG11635 - - - - 39431 2770.00 15.97 15.8 -0.0154397543467672 Down 0.0666688680491349 Pcaf Gcn5 ortholog K06062|1|0.0|1533|dme:Dmel_CG4107|histone acetyltransferase [EC:2.3.1.48] GO:0070461//SAGA-type complex;GO:0005694//chromosome GO:0004468//lysine N-acetyltransferase activity GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006351//transcription, DNA-dependent;GO:0016573//histone acetylation;GO:0007154//cell communication 3772276 595.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 His2B:CG33882 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 31773 9909.03 11.055 12.04 0.123136366943476 Up 0.201492537313433 Trf2 TATA box binding protein-related factor 2, isoform J K03120|1|8e-77|290|ame:412919|transcription initiation factor TFIID TATA-box-binding protein GO:0005667//transcription factor complex;GO:0043073//germ cell nucleus;GO:0005694//chromosome;GO:0005667//transcription factor complex;GO:0043073//germ cell nucleus;GO:0005694//chromosome GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity GO:0002165//instar larval or pupal development;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0002165//instar larval or pupal development;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0048102//autophagic cell death 33879 657.00 0.245 0.485 0.985202998071919 Up 0.162561088363492 CG13984 CG13984 - - GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process 35896 722.00 3.375 0.795 -2.08586073665384 Down 0.554583278298772 CG13748 CG13748 K08117|1|1e-12|73.2|dre:796801|amyloid beta (A4) precursor-like protein 2;K03909|3|2e-11|69.3|tgu:100228168|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 34677 1790.03 20.67 24.385 0.23845558361042 Up 0.393012812045965 PICK1 PICK1 ortholog, isoform F - - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding - 31175 2045.88 4.82 7.375 0.613609902906604 Up 0.463908334434025 CG4061 CG4061, isoform B K01974|1|0.0|719|dme:Dmel_CG4061|RNA 3'-terminal phosphate cyclase [EC:6.5.1.4] - - - 34921 7815.15 23.155 31.04 0.422804800483434 Up 0.547318716153745 CG4587 CG4587, isoform O K05316|1|0.0|2214|dme:Dmel_CG4587|voltage-dependent calcium channel alpha-2/delta, invertebrate GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - - 36107 2481.00 1.64 1.895 0.208502033553008 Up 0.123464535728437 Caf1-105 Caf1-105 K10751|1|0.0|1444|dme:Dmel_CG12892|chromatin assembly factor 1 subunit B GO:0043234//protein complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 43633 2949.58 293.07 193.58 -0.598315388482133 Down 0.673722097477216 tmod tropomodulin, isoform Q K10370|1|1e-177|624|dse:Dsec_GM12892|tropomodulin GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding - 42906 1676.00 8.87 3.69 -1.26531328824067 Down 0.61943600581165 CG18528 CG18528 K03650|1|0.0|937|dme:Dmel_CG18528|tRNA modification GTPase GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0008033//tRNA processing 35841 764.00 2345.94 1006.59 -1.22068994480379 Down 0.755349359397702 CG8736 CG8736 - - - - 36564 1463.85 9.57 9.905 0.0496380504034606 Up 0.100944393078854 O-fut1 O-fucosyltransferase 1, isoform B K03691|1|0.0|852|dme:Dmel_CG12366|peptide-O-fucosyltransferase [EC:2.4.1.221] GO:0031982//vesicle;GO:0031228//intrinsic to Golgi membrane GO:0008417//fucosyltransferase activity;GO:0005102//receptor binding GO:0016192//vesicle-mediated transport;GO:0048731;GO:0008593//regulation of Notch signaling pathway;GO:0007155//cell adhesion;GO:0006486//protein glycosylation;GO:0009057//macromolecule catabolic process 8674024 1095.00 15.22 14.31 -0.0889446867768777 Down 0.174250429269581 CG42558 CG42558 - - - - 36298 877.00 17.11 12.025 -0.508802865832009 Down 0.536421872936204 skpB skpB K03094|1|8e-89|326|dme:Dmel_CG8881|S-phase kinase-associated protein 1 - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding GO:0019941//modification-dependent protein catabolic process 43649 641.24 153.6 165.965 0.111700810751826 Up 0.279025227843085 Npc2h Niemann-Pick type C-2h, isoform C K13443|1|3e-49|194|dse:Dsec_GM12131|Niemann-Pick C2 protein - - - 50296 2820.55 6.15 7.42 0.270832776394201 Up 0.294809140140008 dpr6 dpr6, isoform F K06550|1|7e-09|63.2|mdo:100028028|L1 cell adhesion molecule;K06774|3|1e-08|62.4|mdo:100017555|neurotrimin - - - 2768917 1326.00 1.765 8.205 2.21683515024253 Up 0.68210936468102 CG33301 CG33301, isoform B - - - - 37861 1533.00 8.54 9.01 0.0772910361930484 Up 0.132082948091401 CG3253 CG3253, isoform B K00741|1|0.0|783|dme:Dmel_CG3253|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149] - GO:0016740//transferase activity - 19834909 538.00 0.305 0.58 0.927243657564686 Up 0.173722097477216 35300 1809.85 1.795 1.875 0.0629067515601919 Up 0.0625412759212786 Kua Kua, isoform D K10704|1|0.0|654|dme:Dmel_CG10723|ubiquitin-conjugating enzyme E2 variant - - - 36897 2351.00 304.955 450.945 0.564355114006148 Up 0.666490556069211 inaC inactivation no afterpotential C K02677|1|0.0|1385|dme:Dmel_CG6518|classical protein kinase C [EC:2.7.11.13] - - - 47218 644.00 780.5 925.565 0.245935678135549 Up 0.4877162858275 RpS14a ribosomal protein S14a, isoform B K02955|1|7e-58|223|dya:Dyak_GE15748|small subunit ribosomal protein S14e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 19835839 553.00 0.08 0.01 -3 Down 0.110718531237617 32975 2395.13 3.55 4.27 0.266417045228446 Up 0.226225069343548 et eye transformer, isoform C K01104|1|2e-21|104|dpe:Dper_GL18308|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part GO:0004888//transmembrane signaling receptor activity - 3772666 412.00 0.01 0.645 6.01122725542325 Up 0.410513802668076 His4:CG33907 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 31446 1883.00 0.025 0.03 0.263034405833794 Up 0.0467903843613789 CG15930 CG15930 - - - - 41540 1746.00 28.905 33.67 0.220144648810769 Up 0.394267600052833 trus toys are us - - - - 40793 9091.28 13.72 16.625 0.277073859103102 Up 0.397635715229164 gpp grappa, isoform F K11427|1|0.0|2514|dme:Dmel_CG10272|histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43] - GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity - 36583 2793.65 103.51 114.56 0.146333245898423 Up 0.342953374719324 Hsc70-5 heat shock protein cognate 5, isoform B K04043|1|0.0|1229|dme:Dmel_CG8542|molecular chaperone DnaK GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006950//response to stress;GO:0044267//cellular protein metabolic process 40292 3996.55 71.03 92.235 0.376885822218578 Up 0.573107911768591 Pitslre pitslre, isoform G K08818|1|0.0|1260|dme:Dmel_CG4268|cell division cycle 2-like [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0065008;GO:0006464//cellular protein modification process;GO:0007049//cell cycle;GO:0065008;GO:0006464//cellular protein modification process;GO:0007049//cell cycle 42653 1921.00 22.095 21.545 -0.0363668326466226 Down 0.11028926165632 CG5346 CG5346 K06892|1|4e-31|136|spu:760899| - GO:0003824//catalytic activity GO:0008152//metabolic process 43485 1647.00 0.19 0.34 0.839535327806754 Up 0.124025888257826 ppk21 pickpocket 21, isoform B K04832|1|2e-09|64.3|mmu:58170|amiloride-sensitive cation channel 5, intestinal;K04828|2|2e-08|60.8|gga:419945|amiloride-sensitive cation channel 1, neuronal (degenerin) GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 38461 1491.14 14.91 15.555 0.0610981372509395 Up 0.133998150838727 CG10866 CG10866, isoform B - - - - 31990 1540.98 17.4 12.365 -0.492825066346153 Down 0.531105534275525 CG1628 CG1628, isoform C K03454|1|1e-38|161|tad:TRIADDRAFT_25969|mitochondrial carrier protein, MC family GO:0031224//intrinsic to membrane - GO:0006810//transport 5740313 458.26 13.165 11.4 -0.207673696993959 Down 0.307588165367851 CG34423 CG34423, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0016882//cyclo-ligase activity;GO:0030234//enzyme regulator activity;GO:0032559 GO:0006760//folic acid-containing compound metabolic process;GO:0006140 117300 1844.00 15.96 17.59 0.140294831249615 Up 0.254490820235108 clt cricklet K01044|1|0.0|1115|dme:Dmel_CG9858|carboxylesterase [EC:3.1.1.1];K03927|2|1e-76|287|dmo:Dmoj_GI23478|carboxylesterase type B [EC:3.1.1.1] - GO:0016788//hydrolase activity, acting on ester bonds - 40613 1116.00 181.4 80.27 -1.17624165314922 Down 0.745377096816801 CG1124 CG1124 - - - - 2768847 914.00 0.09 0.86 3.25633975325979 Up 0.369006736230353 CG33459 CG33459 K09632|1|3e-26|119|hsa:1506|chymotrypsin-like protease [EC:3.4.21.-];K01323|2|1e-25|117|ptr:461643|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 53561 7008.00 0.1 0.205 1.03562390973072 Up 0.112336547351737 cmet CENP-meta, isoform F K11498|1|0.0|3790|dme:Dmel_CG6392|centromeric protein E GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 34016 1158.89 58.195 60.69 0.0605636156810329 Up 0.170221899352794 CG5171 CG5171, isoform F K01087|1|7e-156|550|dme:Dmel_CG5171|trehalose-phosphatase [EC:3.1.3.12] - - GO:0005991//trehalose metabolic process;GO:0005991//trehalose metabolic process;GO:0005991//trehalose metabolic process;GO:0005991//trehalose metabolic process 37830 1748.00 1.065 1.015 -0.069373703040662 Down 0.0561022322018227 CG4324 CG4324, isoform C K06258|1|5e-34|145|tad:TRIADDRAFT_36521|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 GO:0031224//intrinsic to membrane - GO:0006810//transport 37989 941.95 64.82 57.705 -0.167742690300069 Down 0.359992075023115 Tina-1 troponin C-akin-1, isoform B - - GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0048513//organ development;GO:0048513//organ development 31717 3300.11 36.73 45.55 0.310492157957755 Up 0.499636771892749 sn singed, isoform G - GO:0005884//actin filament GO:0046914//transition metal ion binding;GO:0003779//actin binding GO:0016477//cell migration;GO:0003002//regionalization;GO:0048858//cell projection morphogenesis;GO:0051017//actin filament bundle assembly;GO:0009611//response to wounding;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007292//female gamete generation 33975 2142.00 2.18 2.165 -0.00996111005020131 Down 0.041044776119403 CG13775 CG13775, isoform C - - GO:0005515//protein binding;GO:0003676//nucleic acid binding - 34363 916.58 115.505 111.895 -0.0458097333316457 Down 0.154669132215031 eEF1delta eEF1delta, isoform B K03232|1|5e-94|343|dme:Dmel_CG4912|elongation factor EF-1 beta subunit GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding;GO:0030695//GTPase regulator activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0030695//GTPase regulator activity GO:0006412//translation;GO:0006412//translation 43560 926.85 40.785 44.895 0.138516127473341 Up 0.304847444194954 Nlp nucleoplasmin, isoform B K11278|1|1e-56|219|dme:Dmel_CG7917|nucleophosmin 3;K11276|5|5e-09|62.0|hmg:100215712|nucleophosmin 1 GO:0031981//nuclear lumen GO:0016887//ATPase activity;GO:0005515//protein binding GO:0034728//nucleosome organization 19835473 438.00 2.965 3.055 0.0431402752727258 Up 0.0622440892880729 41982 1379.73 0.985 2.565 1.38076319615068 Up 0.442907145687492 CG14879 CG14879, isoform D - - - - 47877 3255.75 38.515 38.07 -0.0167658554149137 Down 0.081858407079646 tws twins, isoform I K04354|1|0.0|881|dsi:Dsim_GD20732|protein phosphatase 2 (formerly 2A), regulatory subunit B GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0023060;GO:0030011//maintenance of cell polarity;GO:0048513//organ development;GO:0007067//mitosis;GO:0007405//neuroblast proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process 33379 4129.70 29.59 27.815 -0.0892465909403088 Down 0.205719191652358 Su(dx) suppressor of deltex, isoform F K05633|1|0.0|1700|dme:Dmel_CG4244|atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:6.3.2.19] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005102//receptor binding;GO:0019787//small conjugating protein ligase activity;GO:0005102//receptor binding;GO:0019787//small conjugating protein ligase activity;GO:0005102//receptor binding;GO:0019787//small conjugating protein ligase activity GO:0007480//imaginal disc-derived leg morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0010876//lipid localization;GO:0006898//receptor-mediated endocytosis;GO:0043412//macromolecule modification;GO:0008104//protein localization;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0010876//lipid localization;GO:0006898//receptor-mediated endocytosis;GO:0043412//macromolecule modification;GO:0008104//protein localization;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0010876//lipid localization;GO:0006898//receptor-mediated endocytosis;GO:0043412//macromolecule modification;GO:0008104//protein localization 35639 1432.00 7.32 6.065 -0.271336003163532 Down 0.294082683925505 Spn43Ad serpin 43Ad K13963|1|1e-26|121|dvi:Dvir_GJ18486|serpin B - GO:0004866//endopeptidase inhibitor activity - 39730 5027.30 19.09 24.47 0.358196998675452 Up 0.495839387135121 pHCl pHCl, isoform R K05273|1|1e-43|179|cbr:CBG03919|glutamate receptor, anionic, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005253//anion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005253//anion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005253//anion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005253//anion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005253//anion channel activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 14462727 345.00 0.93 0.43 -1.11289405640593 Down 0.250297186633206 2768957 267.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 CG33500 CG33500 - - - - 38828 1483.00 0.105 1.54 3.87446911791614 Up 0.49953770968168 CG8562 CG8562 K01290|1|1e-55|217|dan:Dana_GF14014|carboxypeptidase A, invertebrate [EC:3.4.17.-];K01291|2|9e-53|207|mmu:76703|carboxypeptidase B [EC:3.4.17.2] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 33857 575.00 31.42 35.615 0.180801809655494 Up 0.350911372341831 CG13993 CG13993, isoform B K09548|1|7e-54|209|dme:Dmel_CG13993|prefoldin subunit 1 GO:0043234//protein complex GO:0005515//protein binding GO:0044267//cellular protein metabolic process 32531 2427.87 10.495 10.51 0.00206050267002399 Up 0.0401862369568089 Rhp rhophilin, isoform B K01104|1|2e-30|134|dre:100007322|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part;GO:0044464//cell part GO:0017048//Rho GTPase binding;GO:0017048//Rho GTPase binding GO:0023060;GO:0023060 41437 4630.00 4.51 4.815 0.0944083645880784 Up 0.111180821555937 CG31368 CG31368, isoform D K12874|1|0.0|2805|dme:Dmel_CG31368|intron-binding protein aquarius GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377;GO:0000377 14462548 553.26 0.745 0.595 -0.324350757154218 Down 0.108440100383041 42842 515.29 12.39 10.945 -0.178904232959655 Down 0.272487121912561 LSm3 LSm3, isoform B K12622|1|2e-40|164|dme:Dmel_CG31184|U6 snRNA-associated Sm-like protein LSm3 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000377;GO:0022618//ribonucleoprotein complex assembly;GO:0000377;GO:0022618//ribonucleoprotein complex assembly 31130 5946.04 52.04 60.115 0.208104057591406 Up 0.409093910976093 Adar adenosine deaminase acting on RNA, isoform P K13194|1|0.0|1204|dya:Dyak_GE16707|double stranded RNA-specific editase 1 [EC:3.5.-.-] - - - 34652 1119.93 363.17 393.29 0.114948471650575 Up 0.284539690925901 vir-1 virus-induced RNA 1, isoform H - - - - 34304 7026.70 19.14 12.645 -0.598023792822787 Down 0.579084665169727 nAcRalpha-30D nicotinic acetylcholine receptor alpha6, isoform H K04809|1|1e-127|457|gga:374001|nicotinic acetylcholine receptor alpha-7 GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0009636//response to toxic substance;GO:0006810//transport;GO:0009636//response to toxic substance;GO:0006810//transport;GO:0009636//response to toxic substance;GO:0006810//transport;GO:0009636//response to toxic substance;GO:0006810//transport;GO:0009636//response to toxic substance;GO:0006810//transport;GO:0009636//response to toxic substance;GO:0006810//transport 44701 1397.36 10.34 13.39 0.372919775009376 Up 0.44208162726192 Coprox coproporphyrinogen oxidase, isoform B K00228|1|0.0|813|dme:Dmel_CG3433|coproporphyrinogen III oxidase [EC:1.3.3.3] GO:0043231//intracellular membrane-bounded organelle GO:0016634 GO:0006779//porphyrin-containing compound biosynthetic process 40630 867.00 22.335 26.24 0.232461465314828 Up 0.389743759080703 CG12173 CG12173 K09880|1|3e-144|510|dme:Dmel_CG12173|enolase-phosphatase E1 [EC:3.1.3.77] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016791//phosphatase activity GO:0043102;GO:0000097//sulfur amino acid biosynthetic process 12798445 455.00 0.28 0.31 0.146841388329271 Up 0.0552767137762515 CG43058 CG43058 - - - - 31605 1724.25 176.29 161.6 -0.125523442424408 Down 0.316272619204861 l(1)G0255 lethal (1) G0255, isoform B K01679|1|0.0|894|dse:Dsec_GM12511|fumarate hydratase, class II [EC:4.2.1.2] - - - 34623 2189.03 94.03 55.53 -0.759853721990174 Down 0.690991942940166 CG14945 CG14945, isoform B - - GO:0004620//phospholipase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0004620//phospholipase activity;GO:0042578//phosphoric ester hydrolase activity GO:0023033;GO:0006644//phospholipid metabolic process;GO:0023033;GO:0006644//phospholipid metabolic process 42529 495.00 141.79 41.57 -1.77014113437458 Down 0.776350548144235 CG17298 CG17298 - - - - 34711 1557.00 30.82 35.375 0.198863286091822 Up 0.374554220050192 CG5287 CG5287 K01001|1|0.0|772|dme:Dmel_CG5287|UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] GO:0031224//intrinsic to membrane GO:0016780//phosphotransferase activity, for other substituted phosphate groups - 45280 4329.00 8.945 7.46 -0.261905851796671 Down 0.309404305904108 cv-2 crossveinless 2 K03900|1|7e-35|150|gga:419031|von Willebrand factor - - - 8674020 330.00 1.19 0.9 -0.402964666978269 Down 0.155494650640602 CG42471 CG42471 - - - - 44839 6524.70 0.28 0.61 1.12338241550528 Up 0.200964205521067 mud mushroom body defect, isoform L K12478|1|3e-34|149|bta:516259|early endosome antigen 1 GO:0005815//microtubule organizing center;GO:0044448//cell cortex part;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044448//cell cortex part;GO:0043231//intracellular membrane-bounded organelle;GO:0044448//cell cortex part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016209//antioxidant activity;GO:0043169//cation binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016209//antioxidant activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0043169//cation binding;GO:0016209//antioxidant activity GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0007420//brain development;GO:0007056//spindle assembly involved in female meiosis;GO:0045165//cell fate commitment;GO:0006351//transcription, DNA-dependent;GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0007420//brain development;GO:0007056//spindle assembly involved in female meiosis;GO:0045165//cell fate commitment;GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0007056//spindle assembly involved in female meiosis;GO:0007420//brain development;GO:0006800//oxygen and reactive oxygen species metabolic process 19835299 263.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 33386 3003.41 508.155 387.77 -0.39006742922726 Down 0.59893012812046 GlyP glycogen phosphorylase, isoform B K00688|1|0.0|1643|dme:Dmel_CG7254|starch phosphorylase [EC:2.4.1.1] GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0042802//identical protein binding;GO:0004645//phosphorylase activity;GO:0048037//cofactor binding;GO:0042802//identical protein binding;GO:0004645//phosphorylase activity;GO:0048037//cofactor binding GO:0040011//locomotion;GO:0005977//glycogen metabolic process;GO:0040011//locomotion;GO:0005977//glycogen metabolic process 3355097 681.19 18.07 17.545 -0.0425365584624328 Down 0.10890239070136 Gpb5 glycoprotein hormone beta 5 ortholog, isoform D - - GO:0046983//protein dimerization activity;GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0005102//receptor binding - 117346 1135.76 1.86 1.97 0.0828930083483448 Up 0.0714238541804253 Gr39a gustatory receptor 39a, isoform D K08471|1|6e-16|85.1|dme:Dmel_CG14916|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity GO:0007606//sensory perception of chemical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 2768865 1362.69 117.555 130.67 0.15259205374344 Up 0.345793158103289 dpr7 dpr7, isoform G K06768|1|8e-08|58.2|dre:100002762|Down syndrome cell adhesion molecule like 1;K06765|2|4e-07|55.8|mmu:13176|deleted in colorectal carcinoma;K12567|4|6e-07|55.1|hsa:7273|titin [EC:2.7.11.1] - - - 38830 1464.16 1.22 2.67 1.12995859412467 Up 0.414773477744023 CG8560 CG8560, isoform B K01298|1|3e-60|233|rno:296959|carboxypeptidase A2 [EC:3.4.17.15] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 40982 1085.00 38.72 36.56 -0.0828128822165246 Down 0.197662131818782 Sgt1 suppressor-of-G2-allele-of-skp1 K12795|1|1e-89|329|dme:Dmel_CG9617|suppressor of G2 allele of SKP1 - - GO:0031023//microtubule organizing center organization 44879 1570.00 0.275 0.09 -1.61143471208235 Down 0.157343811913882 rhi rhino K11585|1|8e-10|65.5|xla:444708|chromobox protein 1;K11587|2|1e-09|64.7|rno:300266|chromobox protein 5 GO:0043231//intracellular membrane-bounded organelle - GO:0003002//regionalization;GO:0009987//cellular process 35225 4952.15 9.855 9.625 -0.0340693305738597 Down 0.0789195614846123 Top2 topoisomerase 2, isoform B K03164|1|0.0|2471|dme:Dmel_CG10223|DNA topoisomerase II [EC:5.99.1.3] GO:0016585//chromatin remodeling complex;GO:0000267//cell fraction;GO:0005678//chromatin assembly complex;GO:0043232 GO:0003916//DNA topoisomerase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0032559;GO:0043565//sequence-specific DNA binding;GO:0000217//DNA secondary structure binding;GO:0003723//RNA binding GO:0006351//transcription, DNA-dependent;GO:0016458//gene silencing;GO:0051303//establishment of chromosome localization;GO:0006259//DNA metabolic process;GO:0000070//mitotic sister chromatid segregation 43127 3343.00 27.215 28.825 0.0829185718140405 Up 0.188515387663453 Tsp96F tetraspanin 96F, isoform C K06508|1|1e-144|514|dme:Dmel_CG6120|CD81 antigen GO:0031224//intrinsic to membrane - - 3355138 1804.00 32.265 33.175 0.0401264401133383 Up 0.120855897503632 CG17486 CG17486 K01953|1|3e-06|53.9|cbr:CBG01494|asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] - GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0046914//transition metal ion binding GO:0006528//asparagine metabolic process 260659 7203.00 0.96 0.44 -1.12553088208386 Down 0.256042794875182 CG31817 CG31817 - - - - 47137 2674.00 17.455 4.73 -1.88372826821336 Down 0.722163518689737 knk knickkopf - - GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0035151//regulation of tube size, open tracheal system;GO:0016331//morphogenesis of embryonic epithelium;GO:0040003//chitin-based cuticle development;GO:0006031//chitin biosynthetic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006547//histidine metabolic process 14462553 808.00 0.155 0.25 0.68965987938785 Up 0.0993593977017567 14462434 538.00 1.735 1.135 -0.612243365287346 Down 0.244287412495047 CG44088 CG44088 - - - - 35195 708.00 21.095 22.575 0.0978249001488696 Up 0.209747721569145 l(2)37Ce lethal (2) 37Ce K10428|1|3e-103|374|dme:Dmel_CG17347|dynactin 6 GO:0005875//microtubule associated complex GO:0005515//protein binding;GO:0003824//catalytic activity GO:0007017//microtubule-based process;GO:0008152//metabolic process 43289 784.00 39.08 38.4 -0.0253241563598668 Down 0.101604807819311 CG5934 CG5934 - - - - 5740535 559.00 0.01 1.76 7.4594316186373 Up 0.632016906617356 35399 938.46 30.305 32.865 0.116996142502924 Up 0.260434552899221 l(2)k14505 lethal (2) k14505, isoform B K07556|1|3e-158|557|dme:Dmel_CG8674|ATP synthase mitochondrial F1 complex assembly factor 2 - GO:0005488//binding GO:0070071 33357 541.00 0.305 0.255 -0.258311995591391 Down 0.0686501122705059 CG17648 CG17648 - - - - 36042 3329.04 9.06 8.895 -0.0265164447790755 Down 0.0722493726059966 CG12128 CG12128, isoform B K09142|1|0.0|840|dme:Dmel_CG12128|hypothetical protein - - - 42169 3321.40 68.475 80.155 0.227215156332695 Up 0.440859859992075 PP2A-B' PP2A-B', isoform Q K11584|1|0.0|927|dme:Dmel_CG7913|protein phosphatase 2 (formerly 2A), regulatory subunit B' GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex GO:0019888//protein phosphatase regulator activity;GO:0019888//protein phosphatase regulator activity;GO:0019888//protein phosphatase regulator activity GO:0048741//skeletal muscle fiber development;GO:0007268//synaptic transmission;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0048741//skeletal muscle fiber development;GO:0007268//synaptic transmission;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0048741//skeletal muscle fiber development;GO:0007268//synaptic transmission;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process 36706 4454.78 34.235 38.49 0.169011658718703 Up 0.34117025492009 SRPK SRPK, isoform D K08831|1|0.0|925|dme:Dmel_CG8174|SFRS protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 19834932 784.00 0.01 0.125 3.64385618977472 Up 0.151697265882974 36061 2488.73 20.81 21.77 0.0650644424528722 Up 0.15790516444327 CG11866 dampened, isoform B K10306|1|0.0|832|dan:Dana_GF13725|F-box protein 28 - - - 42629 2337.00 0.375 0.475 0.341036917835067 Up 0.0924250429269581 CG13855 CG13855 - - - - 40852 1657.00 18.795 17.78 -0.0800935912132468 Down 0.171212521463479 CG10068 CG10068 - GO:0043232 - GO:0006897//endocytosis;GO:0051301//cell division 5740166 668.00 420.47 479.01 0.1880529048463 Up 0.4158961828028 33765 2697.47 15.9 17.45 0.134200270925297 Up 0.243098665962224 fusl fuseless, isoform F - GO:0016020//membrane;GO:0033267//axon part;GO:0016020//membrane;GO:0033267//axon part - GO:0007268//synaptic transmission;GO:0007268//synaptic transmission 3346227 2616.85 7.87 9.115 0.211879020531648 Up 0.270704002113327 dpr2 dpr2, isoform G K06772|1|1e-06|55.1|mdo:100011758|limbic system-associated membrane protein;K06775|2|1e-06|54.7|oaa:100077955|neuronal growth regulator 1 - - - 36551 2956.00 0.97 1.325 0.449935707263434 Up 0.178807290978735 Ctf4 Ctf4 K11274|1|0.0|1697|dme:Dmel_CG13350|chromosome transmission fidelity protein 4 - - - 43767 4944.39 13.945 10.905 -0.354758164387562 Down 0.434651961431779 ci cubitus interruptus, isoform C K06230|1|0.0|2514|dme:Dmel_CG2125|zinc finger protein GLI - - - 19835847 2897.00 0.055 0.15 1.44745897697122 Up 0.105204068154801 14462530 702.00 0.01 0.38 5.24792751344359 Up 0.310130762118611 19834756 326.00 1.53 0.48 -1.6724253419715 Down 0.381158367454762 35987 493.00 9.625 11.07 0.201796776311926 Up 0.282525425967508 CG12929 CG12929, isoform B - - - - 37528 3965.63 21.83 22.54 0.04617538518143 Up 0.127360982697134 Fmr1 Fmr1, isoform I - GO:0031332;GO:0044444//cytoplasmic part;GO:0031332;GO:0044444//cytoplasmic part;GO:0031332;GO:0044444//cytoplasmic part;GO:0031332;GO:0044444//cytoplasmic part;GO:0031332;GO:0044444//cytoplasmic part;GO:0031332;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0007420//brain development;GO:0007613//memory;GO:0008306//associative learning;GO:0001505//regulation of neurotransmitter levels;GO:0009416//response to light stimulus;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0022410;GO:0000278//mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0008283//cell proliferation;GO:0006338//chromatin remodeling;GO:0006412//translation;GO:0031345//negative regulation of cell projection organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0007420//brain development;GO:0007613//memory;GO:0008306//associative learning;GO:0001505//regulation of neurotransmitter levels;GO:0009416//response to light stimulus;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0022410;GO:0000278//mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0008283//cell proliferation;GO:0006338//chromatin remodeling;GO:0006412//translation;GO:0031345//negative regulation of cell projection organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0007420//brain development;GO:0007613//memory;GO:0008306//associative learning;GO:0001505//regulation of neurotransmitter levels;GO:0009416//response to light stimulus;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0022410;GO:0000278//mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0008283//cell proliferation;GO:0006338//chromatin remodeling;GO:0006412//translation;GO:0031345//negative regulation of cell projection organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0007420//brain development;GO:0007613//memory;GO:0008306//associative learning;GO:0001505//regulation of neurotransmitter levels;GO:0009416//response to light stimulus;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0022410;GO:0000278//mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0008283//cell proliferation;GO:0006338//chromatin remodeling;GO:0006412//translation;GO:0031345//negative regulation of cell projection organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0007420//brain development;GO:0007613//memory;GO:0008306//associative learning;GO:0001505//regulation of neurotransmitter levels;GO:0009416//response to light stimulus;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0022410;GO:0000278//mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0008283//cell proliferation;GO:0006338//chromatin remodeling;GO:0006412//translation;GO:0031345//negative regulation of cell projection organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0007420//brain development;GO:0007613//memory;GO:0008306//associative learning;GO:0001505//regulation of neurotransmitter levels;GO:0009416//response to light stimulus;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0022410;GO:0000278//mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0008283//cell proliferation;GO:0006338//chromatin remodeling;GO:0006412//translation;GO:0031345//negative regulation of cell projection organization;GO:0010769//regulation of cell morphogenesis involved in differentiation 33171 2842.84 294.965 213.895 -0.463641018589392 Down 0.62987055871087 CG3164 CG3164, isoform D K05680|1|7e-154|545|cin:100179107|ATP-binding cassette, subfamily G (WHITE), member 4;K05679|2|7e-154|545|bfo:BRAFLDRAFT_82876|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559 - 38013 3413.00 11.37 20.955 0.882062267238371 Up 0.647437590807027 mthl8 methuselah-like 8, isoform B K04599|1|3e-23|111|dme:Dmel_CG6936|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0010259//multicellular organismal aging 45460 3275.00 6.515 4.745 -0.457357091547025 Down 0.385913353586052 Pex1 peroxin 1 K13338|1|0.0|1921|dme:Dmel_CG6760|peroxin-1 GO:0031224//intrinsic to membrane;GO:0042579//microbody GO:0004871//signal transducer activity;GO:0004672//protein kinase activity;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006996//organelle organization 12798275 534.00 0.08 0.175 1.12928301694497 Up 0.107647602694492 CG43447 CG43447 - - - - 43259 1054.00 322.64 111.515 -1.53268752923004 Down 0.771100250957601 Cpr97Eb cuticular protein 97Eb - - GO:0005198//structural molecule activity - 41648 1273.68 60.115 81.425 0.437746794974064 Up 0.600416061286488 CCHa2 CCHamide-2, isoform C - - - - 35532 2080.00 29.15 35.065 0.266535844585167 Up 0.446638488971074 tbce Tubulin-specific chaperone E, isoform C K10392|1|1e-07|58.9|tgu:100229907|kinesin family member 1/13/14;K10421|4|7e-06|52.8|ssc:100153677|CAP-Gly domain-containing linker protein 1 - - - 37943 1557.00 0.295 0.28 -0.075288127304237 Down 0.0426627922335227 CG4781 CG4781 K13023|1|1e-16|88.2|oaa:100081004|carboxypeptidase N regulatory subunit;K10161|2|1e-14|81.6|ecb:100009693|toll-like receptor 9 - GO:0005488//binding - 30975 3523.34 25 27.765 0.151339301042281 Up 0.299332981112138 ewg erect wing, isoform N K11831|1|0.0|1036|der:Dere_GG12766|nuclear respiratory factor 1 - - - 31745 1586.00 4.09 3.725 -0.134860417592225 Down 0.136606789063532 CG18262 CG18262 K09228|1|4e-47|189|ptr:469069|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 32036 717.00 36.085 33.48 -0.108099726875368 Down 0.248117817989698 CG1545 CG1545 - - - - 39797 544.00 16.96 7.495 -1.17813578661534 Down 0.670519085985999 CG13063 CG13063 - - - - 3772509 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33887 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 43217 1498.56 19.93 17.88 -0.15659497365574 Down 0.287544577994981 CG5484 CG5484, isoform C - - - - 32209 7499.32 18.155 19.59 0.10975046746738 Up 0.218597279091269 Sec16 Sec16 ortholog, isoform J - GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane - GO:0006996//organelle organization;GO:0006886//intracellular protein transport;GO:0006996//organelle organization;GO:0006886//intracellular protein transport 34003 4145.93 50.07 43.3 -0.209579430469668 Down 0.402720908730683 CG13784 CG13784, isoform F - - - - 38580 14293.43 14.58 21.04 0.529143984965365 Up 0.565017831197992 Dhc64C dynein heavy chain 64C, isoform I K10413|1|0.0|9031|dme:Dmel_CG7507|dynein heavy chain 1, cytosolic GO:0005875//microtubule associated complex;GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 38963 7644.74 36.34 43.675 0.265249283570006 Up 0.458492933562277 Unr upstream of N-ras, isoform E K01490|1|5e-09|64.3|oaa:100074630|AMP deaminase [EC:3.5.4.6] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0006412//translation;GO:0006351//transcription, DNA-dependent;GO:0007549//dosage compensation;GO:0006412//translation;GO:0006351//transcription, DNA-dependent;GO:0007549//dosage compensation 246667 653.81 0.32 0.345 0.108524456778169 Up 0.052073702285035 Obp56i Odorant-binding protein 56i, isoform B - - GO:0005488//binding;GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization;GO:0007600//sensory perception;GO:0051234//establishment of localization 14462896 533.00 0.01 0.19 4.24792751344359 Up 0.201558578787479 35981 1686.00 1.715 2.355 0.457518483439971 Up 0.24108440100383 CG1809 CG1809 K01077|1|0.0|1036|dme:Dmel_CG1809|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 37964 863.00 8.085 6.71 -0.268935007273478 Down 0.304814423457932 Eap Exu-associated protein K11294|1|8e-06|50.8|xla:397919|nucleolin - GO:0005488//binding;GO:0016780//phosphotransferase activity, for other substituted phosphate groups GO:0006464//cellular protein modification process 38434 1690.16 16.43 8.835 -0.895030440398457 Down 0.630398890503236 CG10359 CG10359, isoform G K10104|1|4e-35|149|dwi:Dwil_GK15354|ficolin;K05465|3|7e-33|142|xla:444230|angiopoietin 1;K05467|4|3e-32|140|cfa:609626|angiopoietin 4 - GO:0005515//protein binding;GO:0005515//protein binding GO:0023060;GO:0023060 41710 837.26 321.645 142.23 -1.17724346313863 Down 0.749933958525954 Npc2b Niemann-Pick type C-2b, isoform B K13443|1|5e-29|127|phu:Phum_PHUM074050|Niemann-Pick C2 protein - - - 39315 952.00 14.73 12.315 -0.258340802536888 Down 0.365803724739136 pallidin pallidin ortholog - - - - 44263 4621.00 23.505 21.81 -0.107977910552986 Down 0.228536520935147 Sara smad anchor for receptor activation K04679|1|0.0|2296|dme:Dmel_CG15667|MAD, mothers against decapentaplegic interacting protein GO:0005768//endosome GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding GO:0033036 14462735 1087.00 17.465 14.73 -0.245709212359015 Down 0.372903183199049 33631 1595.00 0.665 0.4 -0.733354340613827 Down 0.160844010038304 Art2 arginine methyltransferase 2, isoform B K11434|1|5e-82|305|dsi:Dsim_GD20702|protein arginine N-methyltransferase 1 [EC:2.1.1.-] GO:0044424//intracellular part GO:0008168//methyltransferase activity GO:0008213 19835249 702.00 1.48 1.65 0.156868848616866 Up 0.098632941487254 19835921 2496.00 0.03 0.035 0.222392421336448 Up 0.0461960110949676 3355130 3073.13 30.5 39.91 0.387941036173661 Up 0.547021529520539 lt light, isoform F - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0050658//RNA transport;GO:0010259//multicellular organismal aging;GO:0042441//eye pigment metabolic process;GO:0007034//vacuolar transport;GO:0006996//organelle organization;GO:0015031//protein transport;GO:0050658//RNA transport;GO:0010259//multicellular organismal aging;GO:0042441//eye pigment metabolic process;GO:0007034//vacuolar transport;GO:0006996//organelle organization;GO:0015031//protein transport;GO:0050658//RNA transport;GO:0010259//multicellular organismal aging;GO:0042441//eye pigment metabolic process;GO:0007034//vacuolar transport;GO:0006996//organelle organization;GO:0015031//protein transport 19835584 1275.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 41662 568.00 0.095 0.895 3.23588826382067 Up 0.375247655527671 CG9757 CG9757, isoform B - - - - 38095 911.00 6.435 7.555 0.231491606944127 Up 0.266081098930128 CG13901 CG13901, isoform B - - - - 31395 2526.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 CG3081 CG3081, isoform B - - - - 19834864 282.00 0.67 0.22 -1.60665757182047 Down 0.252014264958394 43054 1382.00 1.74 1.15 -0.597453444904353 Down 0.241183463214899 CG31104 CG31104 - - - - 34010 2853.96 9.545 10.46 0.132065748843004 Up 0.204398362171444 Wnt6 Wnt oncogene analog 6, isoform C K00445|1|0.0|755|dme:Dmel_CG4969|wingless-type MMTV integration site family, member 6 GO:0031012//extracellular matrix;GO:0016020//membrane GO:0060089;GO:0005102//receptor binding GO:0003002//regionalization;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032583 33237 1093.00 29.57 25.095 -0.236734297360815 Down 0.405692775062739 cold coiled, isoform B - - - - 38103 7346.39 6.55 6.37 -0.0402015341685125 Down 0.0776317527407212 CG32479 CG32479, isoform C K11841|1|0.0|1767|dme:Dmel_CG32479|ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process 8674092 3806.00 9.325 8.73 -0.0951220715131599 Down 0.154900277374191 CG42507 CG42507, isoform B K02174|1|6e-25|117|dme:Dmel_CG11491|broad;K09237|2|3e-19|98.2|dvi:Dvir_GJ23100|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly 318008 6142.00 4.86 3.77 -0.366391790337116 Down 0.300587769119007 jv javelin, isoform D - - GO:0016787//hydrolase activity - 32017 7117.00 10.43 11.55 0.147153693783654 Up 0.232333905692775 CG2186 CG2186, isoform B - - - - 318727 1815.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 Ir94c ionotropic receptor 94c - - - - 2768903 819.00 0.385 0.12 -1.68182403997375 Down 0.186732267864219 CG33252 CG33252 - - - - 14462908 952.00 0.165 0.29 0.813586875769118 Up 0.111279883767006 32261 1438.00 11.455 4.89 -1.22807108835244 Down 0.641725003302074 CG42237 CG42237, isoform B K01047|1|1e-21|104|dme:Dmel_CG3009|phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 5740129 857.00 0.105 0.175 0.736965594166206 Up 0.0868115176330736 CG34206 CG34206 - - - - 326211 1238.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 CG32379 CG32379 K01290|1|2e-53|209|dmo:Dmoj_GI16514|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 32103 934.00 0.585 0.605 0.0484985176911901 Up 0.0451063267732136 CG11697 CG11697, isoform B K11449|1|2e-10|66.6|cfa:474695|jumonji domain-containing protein 1 [EC:1.14.11.-] - - - 40948 1822.00 16.745 16.69 -0.00474642134411693 Down 0.0441487253995509 CG10435 CG10435 - - - - 35610 1675.41 7.97 7.705 -0.0487847674756863 Down 0.0921278562937525 CG17002 CG17002, isoform D - - - - 43539 3320.22 3.38 8.28 1.29260752121714 Up 0.614416853784176 CG31036 CG31036, isoform D - - - - 19835012 636.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 32874 8395.81 36.165 43.88 0.27896937407951 Up 0.469653942676001 CG42450 CG42450, isoform B K13765|1|1e-105|385|oaa:100078978|regulator of G-protein signaling 9 GO:0019897//extrinsic to plasma membrane;GO:0044424//intracellular part GO:0008047//enzyme activator activity;GO:0060089 GO:0007166//cell surface receptor signaling pathway 34288 977.91 24.51 21.17 -0.21134921485925 Down 0.363624356095628 CG13116 CG13116, isoform B - - - - 39764 3714.52 34.595 36.925 0.0940343801355652 Up 0.214568749174482 Zn72D Zinc-finger protein at 72D, isoform F K13203|1|0.0|1414|dsi:Dsim_GD12514|zinc finger RNA-binding protein GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0000377;GO:0006909//phagocytosis;GO:0000377;GO:0006909//phagocytosis 37209 2289.00 5.025 5.335 0.0863646747581338 Up 0.113129045040285 CG11906 CG11906 K09228|1|1e-07|58.5|rno:499143|KRAB domain-containing zinc finger protein;K10519|2|2e-07|58.2|dre:567773|zinc finger and BTB domain-containing protein 48 - - - 40639 1028.52 136.365 91.285 -0.579023683472587 Down 0.660480781931053 Prosbeta7 proteasome beta7 subunit, isoform B K02736|1|4e-156|550|dme:Dmel_CG12000|20S proteasome subunit beta 7 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0031023//microtubule organizing center organization;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007052//mitotic spindle organization;GO:0031023//microtubule organizing center organization;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007052//mitotic spindle organization 36316 2061.18 576.71 47.065 -3.61511953851666 Down 0.848368775591071 Cyp6g1 Cyp6g1, isoform B K00517|1|0.0|974|dme:Dmel_CG8453| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0017085//response to insecticide 36661 1761.00 15.445 10.695 -0.530203388462593 Down 0.533152819970942 Cyp6a23 Cyp6a23 K00517|1|0.0|989|dme:Dmel_CG10242| [EC:1.14.-.-] GO:0042598 GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 33183 1290.00 3.96 3.625 -0.127519435177313 Down 0.131290450402853 CG11617 CG11617, isoform B K09355|1|5e-06|52.4|cqu:CpipJ_CPIJ008039|pre-B-cell leukemia transcription factor GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 33665 3532.00 1.575 1.76 0.160223600250018 Up 0.101142517500991 CG15635 CG15635 K13911|1|3e-34|147|spu:577326|basic salivary proline-rich protein 1/2 - - - 36668 3018.62 54.05 51.1 -0.0809713267970291 Down 0.205322942808083 CG10249 CG10249, isoform J K10380|1|1e-13|78.2|tca:100142605|ankyrin - - - 35630 757.00 0.645 1.255 0.960316298527518 Up 0.269746400739664 CG12836 CG12836, isoform B K11262|1|4e-08|58.5|aag:AaeL_AAEL006307|acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14] - - - 246565 1892.00 5.005 1.4 -1.83794324189103 Down 0.597675340113591 Mal-A6 maltase A6, isoform D K01187|1|0.0|693|dme:Dmel_CG11669|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding GO:0044238//primary metabolic process 33424 1869.00 12.985 12.38 -0.0688346994641428 Down 0.138290846651697 Eogt EGF-domain O-GlcNAc transferase, isoform B - - GO:0016740//transferase activity - 37501 1239.00 0.04 0.045 0.169925001442312 Up 0.0382380134724607 Gr58c gustatory receptor 58c K08471|1|0.0|833|dme:Dmel_CG13491|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0009987//cellular process;GO:0023060 34183 2285.61 5.4 5.275 -0.0337883134562834 Down 0.0651829348831066 CG13096 CG13096, isoform B K06670|1|2e-141|503|dpo:Dpse_GA12044|cohesin complex subunit SCC1 GO:0030529//ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0010467//gene expression 41875 1844.00 23.665 26.765 0.17759273057663 Up 0.334202879408268 CG14868 CG14868 - - - - 318610 1788.00 0.05 0.055 0.137503523749935 Up 0.0448421608770308 Ir94a ionotropic receptor 94a - - - - 32718 5234.80 0.915 0.7 -0.386416821339076 Down 0.133932109364681 f forked, isoform K K10380|1|4e-17|91.7|ecb:100062775|ankyrin GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament;GO:0005884//actin filament GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0003002//regionalization;GO:0007015//actin filament organization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis 31944 1200.00 7.345 7 -0.0694075687239513 Down 0.112072381455554 CG2974 CG2974 K12615|1|8e-06|51.6|bfo:BRAFLDRAFT_61746|enhancer of mRNA-decapping protein 3 - - - 33009 1226.00 2.025 2.44 0.268959239790899 Up 0.171509708096685 CG9570 CG9570 - - - - 33363 3671.47 15.775 17.565 0.15506357135246 Up 0.277935543521331 CG31663 CG31663, isoform C K10316|1|6e-11|70.5|cin:100179677|F-box protein 41 - - GO:0006810//transport 37558 1508.75 148.125 159.07 0.102846620487275 Up 0.259047681944261 CG6044 CG6044, isoform G - - - - 41900 1009.51 5.49 10.445 0.92793443806191 Up 0.590509840179633 CG5399 CG5399, isoform B - - - - 42431 2655.01 39.075 37.575 -0.0564727690832998 Down 0.160844010038304 CG5191 CG5191, isoform F K01426|1|3e-68|260|dpo:Dpse_GA20678|amidase [EC:3.5.1.4];K01175|3|1e-13|79.0|tgu:100230788| [EC:3.1.-.-] - GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds - 31645 1875.00 0.01 0.16 4 Up 0.178939373926826 Inx6 innexin 6 - - - - 32797 5675.72 35.275 39.88 0.177019326913569 Up 0.354939902258618 Frq1 frequenin 1, isoform E K13764|1|2e-42|173|cfa:489500|recoverin GO:0044297//cell body;GO:0030136//clathrin-coated vesicle;GO:0044297//cell body;GO:0030136//clathrin-coated vesicle GO:0030250//guanylate cyclase activator activity;GO:0046872//metal ion binding;GO:0030250//guanylate cyclase activator activity;GO:0046872//metal ion binding GO:0048741//skeletal muscle fiber development;GO:0031175//neuron projection development;GO:0035239//tube morphogenesis;GO:0050804//regulation of synaptic transmission;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0048741//skeletal muscle fiber development;GO:0031175//neuron projection development;GO:0035239//tube morphogenesis;GO:0050804//regulation of synaptic transmission;GO:0032413//negative regulation of ion transmembrane transporter activity 37600 577.00 11.415 14.08 0.302716474412596 Up 0.399848104609695 CG30269 CG30269 - - - - 326113 1633.00 0.14 0.03 -2.22239242133645 Down 0.120954959714701 CG31016 CG31016, isoform C K00472|1|0.0|1078|dme:Dmel_CG31016|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 50268 509.00 10.85 5.81 -0.901084973927313 Down 0.590080570598336 CG13038 CG13038 - - - - 31257 1181.00 30.72 28.35 -0.115829480891565 Down 0.256505085193502 CG2680 CG2680 K01101|1|1e-174|612|dme:Dmel_CG2680|4-nitrophenyl phosphatase [EC:3.1.3.41] - - - 33900 2097.00 60.665 65.615 0.113161252103846 Up 0.265618808611808 frj farjavit, isoform B K13516|1|0.0|915|dme:Dmel_CG9526|lysophospholipid acyltransferase 7 [EC:2.3.1.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 34763 1960.00 1.065 1.515 0.508464363247112 Up 0.204134196275261 Hsp60D Hsp60D, isoform B K04077|1|2e-115|416|dvi:Dvir_GJ15640|chaperonin GroEL - GO:0032559;GO:0032559 GO:0006457//protein folding;GO:0006950//response to stress;GO:0006605//protein targeting;GO:0012501//programmed cell death;GO:0006457//protein folding;GO:0006950//response to stress;GO:0006605//protein targeting;GO:0012501//programmed cell death 12798251 701.00 2.76 3.655 0.405203139174268 Up 0.279355435213314 41474 2853.00 227.31 289.92 0.350993706771895 Up 0.57158895786554 Cpn calphotin, isoform B K12567|1|1e-06|55.8|rno:84015|titin [EC:2.7.11.1];K04006|2|6e-06|53.5|ssc:396743|decay accelerating factor GO:0044424//intracellular part;GO:0044464//cell part GO:0005488//binding GO:0042051//compound eye photoreceptor development;GO:0042051//compound eye photoreceptor development 3354888 2118.64 81.855 81.715 -0.00246961368276887 Down 0.0458658037247391 rl rolled, isoform I K04371|1|3e-66|251|dme:Dmel_CG12559|extracellular signal-regulated kinase 1/2 [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part;GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part;GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part;GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part;GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part;GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part GO:0016909//SAP kinase activity;GO:0032559;GO:0016909//SAP kinase activity;GO:0032559;GO:0016909//SAP kinase activity;GO:0032559;GO:0016909//SAP kinase activity;GO:0032559;GO:0016909//SAP kinase activity;GO:0032559;GO:0016909//SAP kinase activity;GO:0032559 GO:0006351//transcription, DNA-dependent;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0030534//adult behavior;GO:0034331;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0045666//positive regulation of neuron differentiation;GO:0051969;GO:0033554//cellular response to stress;GO:0000087//M phase of mitotic cell cycle;GO:0042051//compound eye photoreceptor development;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-dependent;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0030534//adult behavior;GO:0034331;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0045666//positive regulation of neuron differentiation;GO:0051969;GO:0033554//cellular response to stress;GO:0000087//M phase of mitotic cell cycle;GO:0042051//compound eye photoreceptor development;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-dependent;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0030534//adult behavior;GO:0034331;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0045666//positive regulation of neuron differentiation;GO:0051969;GO:0033554//cellular response to stress;GO:0000087//M phase of mitotic cell cycle;GO:0042051//compound eye photoreceptor development;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-dependent;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0030534//adult behavior;GO:0034331;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0045666//positive regulation of neuron differentiation;GO:0051969;GO:0033554//cellular response to stress;GO:0000087//M phase of mitotic cell cycle;GO:0042051//compound eye photoreceptor development;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-dependent;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0030534//adult behavior;GO:0034331;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0045666//positive regulation of neuron differentiation;GO:0051969;GO:0033554//cellular response to stress;GO:0000087//M phase of mitotic cell cycle;GO:0042051//compound eye photoreceptor development;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-dependent;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0030534//adult behavior;GO:0034331;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0045666//positive regulation of neuron differentiation;GO:0051969;GO:0033554//cellular response to stress;GO:0000087//M phase of mitotic cell cycle;GO:0042051//compound eye photoreceptor development;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process 43241 2221.63 97.045 114.03 0.232687642307488 Up 0.449709417514199 Tsp97E tetraspanin 97E, isoform H K06497|1|3e-06|53.1|nve:NEMVE_v1g236446|CD63 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 19834829 697.25 2.425 1.61 -0.590924058959873 Down 0.284539690925901 326206 1253.00 8.375 8.3 -0.0129778539982098 Down 0.0513802668075551 CG11583 CG11583 - GO:0031981//nuclear lumen GO:0016876//ligase activity, forming aminoacyl-tRNA and related compounds;GO:0032559 GO:0042254//ribosome biogenesis;GO:0010467//gene expression 41054 1964.00 25.305 24.03 -0.0745858258788555 Down 0.169033152819971 Tcp-1eta Tcp-1eta K09499|1|0.0|1021|dme:Dmel_CG8351|T-complex protein 1 subunit eta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0044267//cellular protein metabolic process 38785 4144.81 5.56 4.69 -0.245496960208131 Down 0.241612732796196 melt melted, isoform D - GO:0016020//membrane;GO:0016020//membrane GO:0016564//transcription repressor activity;GO:0035091//phosphatidylinositol binding;GO:0016564//transcription repressor activity;GO:0035091//phosphatidylinositol binding GO:0043704//photoreceptor cell fate specification;GO:0009888//tissue development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019915//lipid storage;GO:0043704//photoreceptor cell fate specification;GO:0009888//tissue development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019915//lipid storage 37786 1499.74 411.145 386.38 -0.089626865562042 Down 0.244419495443138 TM4SF transmembrane 4 superfamily, isoform C K06497|1|1e-12|74.7|dme:Dmel_CG8666|CD63 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 33000 8329.35 17.84 21.665 0.280250621351564 Up 0.42273147536653 Hers histone gene-specific epigenetic repressor in late S phase, isoform I - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 37463 1809.00 1.965 1.87 -0.0714910423709697 Down 0.0656122044644036 CG15674 CG15674, isoform B - - - - 40383 2023.23 30.54 26.97 -0.179344540561248 Down 0.34232598071589 M6 M6, isoform G - - - - 19835803 6900.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 34942 1293.00 0.855 1.235 0.53051471669878 Up 0.188317263241316 CG12448 CG12448 - - - - 37168 1829.15 18.825 27.88 0.566580696309133 Up 0.599953770968168 MFS15 major facilitator superfamily transporter 15, isoform B K08193|1|3e-95|349|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|2|3e-90|332|spu:574944|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - - 47141 4143.54 12.325 13.745 0.15731926024768 Up 0.25891559899617 Exp6 ellipsoid body open, isoform C - - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0022892 GO:0044260;GO:0015031//protein transport 34153 1089.00 21.525 21.08 -0.0301383706469917 Down 0.0950336811517633 Wdr82 Wdr82 K08870|1|6e-135|480|dre:321614|PTK9 protein tyrosine kinase 9;K13124|2|1e-20|100|tad:TRIADDRAFT_21018|mitogen-activated protein kinase organizer 1;K12857|5|3e-18|92.8|nve:NEMVE_v1g239937|Prp8 binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0034708 GO:0018024//histone-lysine N-methyltransferase activity;GO:0004683//calmodulin-dependent protein kinase activity GO:0034968//histone lysine methylation;GO:0007017//microtubule-based process 41440 939.00 0.745 0.74 -0.00971515483321178 Down 0.041044776119403 CG6971 CG6971 K10410|1|3e-138|491|dya:Dyak_GE10075|dynein light intermediate chain, axonemal GO:0005875//microtubule associated complex GO:0016887//ATPase activity - 41743 3758.15 11.55 9.015 -0.357493454871078 Down 0.415698058380663 pr-set7 pr-set7, isoform D K11428|1|0.0|1199|dme:Dmel_CG3307|histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43] - - - 19835282 910.00 8.75 4.46 -0.972239306799387 Down 0.574527803460573 31005 499.00 29.8 40.635 0.447410563573647 Up 0.577598732003698 CG13365 CG13365 - - - - 35997 3603.94 36.605 31.075 -0.236286333256847 Down 0.419198256505085 Mmp2 matrix metalloproteinase 2, isoform D K07763|1|5e-51|203|xla:407753|matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80] GO:0043005//neuron projection;GO:0016020//membrane;GO:0044421//extracellular region part GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0022617//extracellular matrix disassembly;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0007292//female gamete generation;GO:0019538//protein metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007560//imaginal disc morphogenesis;GO:0007424//open tracheal system development 14462577 3036.57 1.285 4.88 1.92511278836901 Up 0.600548144234579 pre-lola-G pre-lola-G, isoform B - - - - 37278 537.00 0.535 0.75 0.487351704094734 Up 0.138819178444063 CG11041 CG11041 K12042|1|9e-15|79.3|dre:58082|troponin C, skeletal muscle;K05865|2|1e-14|79.0|dre:100002038|troponin C, slow skeletal and cardiac muscles;K02183|3|1e-14|79.0|tgu:100231595|calmodulin - - - 38605 6988.54 92.5 107.34 0.214662522482028 Up 0.425703341698587 shep alan shepard, isoform I K13208|1|1e-25|119|mdo:100015949|ELAV like protein 2/3/4 - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0009629//response to gravity;GO:0009629//response to gravity;GO:0009629//response to gravity;GO:0009629//response to gravity;GO:0009629//response to gravity 40183 1384.00 0.61 1.44 1.23918766387943 Up 0.326773213578127 hale hale-bopp - - - - 38514 1605.00 18.205 17.93 -0.02195925257614 Down 0.0745278034605732 CG14997 CG14997, isoform B K00540|1|0.0|894|dme:Dmel_CG14997| [EC:1.-.-.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 19835188 301.00 1.07 0.17 -2.65400414515081 Down 0.38125742966583 40820 580.00 0.075 0.085 0.180572245641821 Up 0.045667679302602 Ccp84Af Ccp84Af - - GO:0042302//structural constituent of cuticle - 40803 1366.00 1.03 1.55 0.589623878091019 Up 0.225399550917976 CG1137 CG1137 - - - - 40727 2184.58 31.675 13.815 -1.19710905721568 Down 0.706610751551975 CG1208 CG1208, isoform C K08145|1|3e-63|243|gga:378802|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity GO:0006810//transport;GO:0006810//transport 33939 3177.79 81.935 89.39 0.125633590590711 Up 0.305805045568617 Nhe3 Na[+]/H[+] hydrogen exchanger 3, isoform J K12041|1|0.0|791|tca:661189|solute carrier family 9, member 6 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport 19834958 422.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 19835020 578.00 1.14 2.345 1.04055409835063 Up 0.379210143970413 19835224 3214.92 7.88 9.94 0.33505022210591 Up 0.381983885880333 33567 2611.00 0.945 0.55 -0.780882710696413 Down 0.20829480914014 CG3238 CG3238, isoform B K01529|1|3e-133|476|dre:326729| [EC:3.6.1.-] - GO:0016462//pyrophosphatase activity;GO:0032559 - 35995 997.00 32.255 23.7 -0.444635757724857 Down 0.560626073173953 GstT1 glutathione S transferase T1 K00799|1|1e-58|226|dme:Dmel_CG1702|glutathione S-transferase [EC:2.5.1.18] - - - 42812 970.88 27.455 29.79 0.117759212305266 Up 0.255877691190067 CG10375 CG10375, isoform B K09528|1|8e-90|330|dsi:Dsim_GD21038|DnaJ homolog subfamily C member 8 - GO:0005515//protein binding - 41641 1170.94 34.385 31.98 -0.104609406774786 Down 0.230517765156518 poly poly, isoform B - - - - 40255 7031.00 1.965 1.75 -0.167174390426278 Down 0.109727909126932 zye zye K10955|1|2e-10|70.1|hsa:4583|intestinal mucin-2 - - - 3355158 1354.35 35.07 38.695 0.141909729028796 Up 0.30038964469687 CG13865 CG13865, isoform C - - - - 42827 1140.50 0.305 0.25 -0.286881147788162 Down 0.0739334301941619 - CG43999, isoform C - - - - 33169 1124.00 0.305 0.45 0.561115758766789 Up 0.116332056531502 CG13694 CG13694, isoform B - - - - 42665 6946.51 27.685 33.255 0.264466749058067 Up 0.435147272487122 Efa6 exchange factor for Arf 6 ortholog, isoform I K12494|1|0.0|1947|dme:Dmel_CG31158|PH and SEC7 domain-containing protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity GO:0032011//ARF protein signal transduction;GO:0032011//ARF protein signal transduction;GO:0032011//ARF protein signal transduction 34931 6001.00 0.245 0.46 0.908852111941804 Up 0.15060758156122 CG18109 CG18109 - GO:0015630//microtubule cytoskeleton;GO:0044430//cytoskeletal part - GO:0007010//cytoskeleton organization 14462676 340.00 0.395 0.18 -1.13385574673479 Down 0.160777968564258 39321 752.00 22.725 20.675 -0.136392965022833 Down 0.270406815480122 crim crimpled - - - - 40161 1801.00 38.78 29.11 -0.413797963984027 Down 0.556234315149914 Cyp305a1 Cyp305a1 K00517|1|4e-73|275|dpo:Dpse_GA17998| [EC:1.14.-.-];K07418|3|2e-62|240|cfa:610195|cytochrome P450, family 2, subfamily J [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 42945 3359.00 1.395 1.2 -0.217230716220669 Down 0.109694888389909 tld tolloid K13045|1|0.0|2216|dme:Dmel_CG6868|tolloid [EC:3.4.24.-];K13046|5|0.0|2049|dse:Dsec_GM26621|tolkin [EC:3.4.24.-] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37884 3313.84 27.09 22.97 -0.238009536824091 Down 0.400244353453969 CG3376 CG3376, isoform D K12350|1|0.0|1394|dme:Dmel_CG3376|sphingomyelin phosphodiesterase [EC:3.1.4.12] - GO:0004620//phospholipase activity;GO:0004620//phospholipase activity GO:0006684//sphingomyelin metabolic process;GO:0006684//sphingomyelin metabolic process 19836009 647.00 3.25 2.27 -0.517747420624902 Down 0.302833179236561 42152 714.00 0.445 0.25 -0.831877241191673 Down 0.140536256769251 CG12347 CG12347, isoform B - - - - 36403 4055.23 15.125 11.96 -0.338717752851214 Down 0.435906749438647 CG42663 CG42663, isoform D - - - - 42820 4955.84 29.36 27.645 -0.0868333964913434 Down 0.203903051116101 CG34355 CG34355, isoform F - - GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0006547//histidine metabolic process 34441 2141.00 8.285 8.915 0.105733100403543 Up 0.164938581429138 Grip75 Grip75 K01769|1|6e-09|63.2|tca:657050|guanylate cyclase, other [EC:4.6.1.2] GO:0000931//gamma-tubulin large complex GO:0005198//structural molecule activity GO:0007056//spindle assembly involved in female meiosis;GO:0000087//M phase of mitotic cell cycle;GO:0033206//cytokinesis after meiosis 41344 1187.00 4.625 4.665 0.0124237154480841 Up 0.0472856954167217 CG4820 CG4820 K09228|1|2e-17|89.7|ptr:468778|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 3355150 2773.00 0.39 0.26 -0.584962500721156 Down 0.11005811649716 AGO3 argonaute 3, isoform G K02156|1|0.0|1699|dme:Dmel_CG40300|aubergine GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0007276//gamete generation;GO:0044238//primary metabolic process;GO:0044260;GO:0016441//posttranscriptional gene silencing;GO:0030154//cell differentiation;GO:0007276//gamete generation;GO:0044238//primary metabolic process;GO:0044260;GO:0016441//posttranscriptional gene silencing;GO:0030154//cell differentiation;GO:0007276//gamete generation;GO:0044238//primary metabolic process;GO:0044260;GO:0016441//posttranscriptional gene silencing;GO:0030154//cell differentiation;GO:0007276//gamete generation;GO:0044238//primary metabolic process;GO:0044260;GO:0016441//posttranscriptional gene silencing;GO:0030154//cell differentiation 31205 3797.66 2.56 3.045 0.250298417906332 Up 0.179929996037512 kz kurz, isoform B K12815|1|9e-51|202|aga:AgaP_AGAP008528|pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 [EC:3.6.4.13] - - - 41268 3628.00 6.16 6.365 0.0472301632064565 Up 0.0851935015189539 CG6325 CG6325 K11791|1|0.0|1607|dme:Dmel_CG6325|DDB1- and CUL4-associated factor 15 - - - 39063 1971.50 36.355 31.545 -0.204742444692053 Down 0.377922335226522 PGRP-LC peptidoglycan recognition protein LC, isoform H K01446|1|6e-155|547|dme:Dmel_CG4432|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0051635//bacterial cell surface binding;GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0051635//bacterial cell surface binding;GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0051635//bacterial cell surface binding;GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0051635//bacterial cell surface binding;GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0051635//bacterial cell surface binding;GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0051635//bacterial cell surface binding;GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0002812;GO:0006897//endocytosis;GO:0002252;GO:0000270//peptidoglycan metabolic process;GO:0002812;GO:0006897//endocytosis;GO:0002252;GO:0000270//peptidoglycan metabolic process;GO:0002812;GO:0006897//endocytosis;GO:0002252;GO:0000270//peptidoglycan metabolic process;GO:0002812;GO:0006897//endocytosis;GO:0002252;GO:0000270//peptidoglycan metabolic process;GO:0002812;GO:0006897//endocytosis;GO:0002252;GO:0000270//peptidoglycan metabolic process;GO:0002812;GO:0006897//endocytosis;GO:0002252 34519 2878.79 39.955 42.725 0.0967044374631653 Up 0.235768062343152 SCAR SCAR, isoform F K06220|1|0.0|943|dme:Dmel_CG4636|WAS protein family - GO:0008092//cytoskeletal protein binding GO:0006909//phagocytosis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0048592//eye morphogenesis;GO:0007409//axonogenesis;GO:0045010//actin nucleation;GO:0007300//ovarian nurse cell to oocyte transport 34485 1914.26 77.555 91.465 0.237999991911214 Up 0.455025756174878 CG17124 CG17124, isoform C - GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005488//binding;GO:0005488//binding GO:0016310//phosphorylation;GO:0016310//phosphorylation 8674108 2082.72 33.825 33.575 -0.0107025345490949 Down 0.0625742966583014 CG42514 CG42514, isoform C - - - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 43717 3064.35 27.22 25.915 -0.0708796731192953 Down 0.169858671245542 gammaCop coat protein (coatomer) gamma, isoform D K10300|1|2e-53|211|tgu:100221878|F-box protein, helicase, 18 [EC:3.6.1.-];K12401|2|8e-12|73.2|mmu:67489|AP-4 complex subunit beta-1;K12391|5|1e-10|69.3|nve:NEMVE_v1g102295|AP-1 complex subunit gamma-1 GO:0030120//vesicle coat;GO:0044431//Golgi apparatus part;GO:0030120//vesicle coat;GO:0044431//Golgi apparatus part;GO:0030120//vesicle coat;GO:0044431//Golgi apparatus part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0043062//extracellular structure organization;GO:0035151//regulation of tube size, open tracheal system;GO:0006909//phagocytosis;GO:0035148//tube formation;GO:0002168//instar larval development;GO:0040003//chitin-based cuticle development;GO:0051301//cell division;GO:0019915//lipid storage;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport;GO:0035146;GO:0043062//extracellular structure organization;GO:0035151//regulation of tube size, open tracheal system;GO:0006909//phagocytosis;GO:0035148//tube formation;GO:0002168//instar larval development;GO:0040003//chitin-based cuticle development;GO:0051301//cell division;GO:0019915//lipid storage;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport;GO:0035146;GO:0043062//extracellular structure organization;GO:0035151//regulation of tube size, open tracheal system;GO:0006909//phagocytosis;GO:0035148//tube formation;GO:0002168//instar larval development;GO:0040003//chitin-based cuticle development;GO:0051301//cell division;GO:0019915//lipid storage;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport;GO:0035146 19835238 1222.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 33776 898.00 12.73 12.56 -0.0193959550097309 Down 0.0666688680491349 CG31648 CG31648 K02258|1|1e-139|495|dme:Dmel_CG31648|cytochrome c oxidase subunit XI assembly protein GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0015002//heme-copper terminal oxidase activity GO:0032501//multicellular organismal process;GO:0043623//cellular protein complex assembly 32292 2382.49 227.1 214.335 -0.0834602507879156 Down 0.221602166160349 CG1640 CG1640, isoform G K00814|1|0.0|1029|dme:Dmel_CG1640|alanine transaminase [EC:2.6.1.2] - GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 32995 656.00 0.185 0.01 -4.20945336562895 Down 0.199412230880993 skpD skpD K03094|1|1e-86|318|dme:Dmel_CG12700|S-phase kinase-associated protein 1 GO:0005815//microtubule organizing center;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding GO:0051276//chromosome organization;GO:0019941//modification-dependent protein catabolic process;GO:0006261//DNA-dependent DNA replication;GO:0046605//regulation of centrosome cycle 37183 496.00 84.95 59.22 -0.520529456894029 Down 0.632380134724607 Dpt diptericin - - - - 36996 3595.00 0.395 0.67 0.762308442280669 Up 0.16658961828028 RhoGAP54D Rho GTPase activating protein at 54D, isoform C K10360|1|2e-08|62.4|ecb:100069995|myosin IX - - - 19834798 665.00 0.565 0.76 0.427748551028398 Up 0.12696473385286 41991 491.00 38.29 45.71 0.255542158753874 Up 0.45053493593977 mRpS33 mitochondrial ribosomal protein S33 - - - - 50007 370.00 41.15 43.48 0.0794595097183209 Up 0.199676396777176 CG11985 CG11985 K12832|1|3e-46|182|dya:Dyak_GE24804|splicing factor 3B subunit 5 GO:0005681//spliceosomal complex - GO:0000278//mitotic cell cycle;GO:0000377 31541 1127.79 10.605 11.475 0.113749532770615 Up 0.186038832386739 CG4666 CG4666, isoform B - - - - 34198 1816.59 2.865 3.91 0.448633468550447 Up 0.304087967243429 CG9314 CG9314, isoform C K03781|1|0.0|1028|dme:Dmel_CG9314|catalase [EC:1.11.1.6] GO:0016020//membrane;GO:0042579//microbody GO:0005506//iron ion binding;GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0010259//multicellular organismal aging;GO:0016337//cell-cell adhesion;GO:0000302//response to reactive oxygen species 33652 1224.00 14.29 14.945 0.064656980582278 Up 0.134823669264298 CG15440 CG15440 K13208|1|2e-12|73.6|cbr:CBG00948|ELAV like protein 2/3/4;K12831|2|3e-12|72.8|dre:192318|splicing factor 3B subunit 4 - GO:0005488//binding - 39645 2410.00 20.025 20.46 0.0310039024492563 Up 0.0945053493593977 CTPsyn CTP synthase, isoform C K01937|1|0.0|1134|dme:Dmel_CG6854|CTP synthase [EC:6.3.4.2] - GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559 GO:0009209;GO:0009064//glutamine family amino acid metabolic process;GO:0009209;GO:0009064//glutamine family amino acid metabolic process 3772101 2694.00 32.59 34.39 0.0775597637882269 Up 0.192808083476423 Ext2 Ext2 K02367|1|0.0|1399|dme:Dmel_CG8433|glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] GO:0005789//endoplasmic reticulum membrane GO:0015020//glucuronosyltransferase activity;GO:0005488//binding;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0008375//acetylglucosaminyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0006818//hydrogen transport;GO:0006041//glucosamine metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 39418 2390.86 3.375 5.58 0.725377619890994 Up 0.456412627129838 toe twin of eyg, isoform B K09381|1|4e-27|123|tad:TRIADDRAFT_3502|paired box protein 3/7;K09383|3|6e-26|119|spu:583610|paired box protein 2/5 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0032501//multicellular organismal process 42435 1207.00 75.62 77.105 0.0280565677712528 Up 0.109727909126932 Elongin-B elongin B K03873|1|5e-61|234|dsi:Dsim_GD20055|transcription elongation factor B, polypeptide 2 GO:0015630//microtubule cytoskeleton GO:0030528//transcription regulator activity;GO:0008135//translation factor activity, nucleic acid binding - 36017 972.00 2.55 2.06 -0.307852909675639 Down 0.195119535068023 Orc6 origin recognition complex subunit 6 K02608|1|5e-122|437|dme:Dmel_CG1584|origin recognition complex subunit 6 GO:0000808//origin recognition complex GO:0003676//nucleic acid binding GO:0016458//gene silencing;GO:0006260//DNA replication;GO:0000087//M phase of mitotic cell cycle 38852 2391.00 0.575 0.82 0.512061953673708 Up 0.145522388059701 CG7716 CG7716 K01769|1|3e-07|57.8|tca:657050|guanylate cyclase, other [EC:4.6.1.2] GO:0015630//microtubule cytoskeleton;GO:0044430//cytoskeletal part GO:0015631//tubulin binding GO:0007051//spindle organization 36523 3427.00 0.835 0.16 -2.38370429247405 Down 0.330108308017435 Cpr50Ca cuticular protein 50Ca - - GO:0005198//structural molecule activity - 33191 7557.00 7.05 8.735 0.309184445630603 Up 0.345396909259015 CG17075 CG17075, isoform B - - GO:0046914//transition metal ion binding - 5740408 3791.00 16.145 4.12 -1.97037119843076 Down 0.721635186897371 CG17707 CG17707, isoform C K00680|1|2e-19|99.0|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 40094 711.75 26.505 26.38 -0.00681997602122842 Down 0.0563994188350284 Bet1 BET1 ortholog, isoform B K08504|1|4e-45|181|dme:Dmel_CG14084|blocked early in transport 1 - GO:0005515//protein binding;GO:0005515//protein binding - 36577 3492.14 28.445 22.505 -0.33792951630921 Down 0.494254391758024 CG8468 CG8468, isoform C K08190|1|2e-35|151|mdo:100014050|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14 - - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 31707 8365.00 16.87 19.27 0.191896598008155 Up 0.324362699775459 CG10777 CG10777, isoform C K13093|1|8e-166|585|tca:655826|HIV Tat-specific factor 1;K12823|2|2e-163|577|tca:100141769|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13];K13178|4|3e-161|570|ame:412313|ATP-dependent RNA helicase DDX17 [EC:3.6.1.-] - - - 40990 2566.00 0.955 0.765 -0.320040985343097 Down 0.121714436666226 Poxm Pox meso K09382|1|1e-81|305|dme:Dmel_CG9610|paired box protein 1/9 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0002164//larval development 19834740 701.00 0.285 0.07 -2.02553509210714 Down 0.17573636243561 19835874 802.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 40668 953.89 51.795 48.555 -0.0931929686442135 Down 0.223220182274468 Pcmt Protein-L-isoaspartate (D-aspartate) O-methyltransferase, isoform C K00573|1|5e-129|460|dme:Dmel_CG2152|protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] GO:0044424//intracellular part GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0044267//cellular protein metabolic process;GO:0043412//macromolecule modification 34598 1955.89 127.515 67.17 -0.924778031904903 Down 0.717507594769515 Mal-B2 maltase B2, isoform D K01187|1|0.0|1151|dme:Dmel_CG14935|alpha-glucosidase [EC:3.2.1.20] - GO:0015926//glucosidase activity;GO:0043167//ion binding;GO:0015926//glucosidase activity;GO:0043167//ion binding;GO:0015926//glucosidase activity;GO:0043167//ion binding GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 19835703 500.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 31971 791.00 0.11 0.12 0.125530882083859 Up 0.0444459120327566 RabX2 RabX2 K07976|1|1e-101|369|dme:Dmel_CG2885|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 31571 3232.00 5.37 4.935 -0.121872003529015 Down 0.144894994056267 CG3815 CG3815 K11642|1|8e-12|73.2|rno:303241|chromodomain-helicase-DNA-binding protein 3 [EC:3.6.1.-];K11643|3|1e-11|72.8|xtr:100124711|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.1.-] - - - 43974 6152.59 69.355 73.485 0.0834498980384904 Up 0.210540219257694 trio trio, isoform F K08810|1|0.0|964|dme:Dmel_CG18214|triple functional domain protein [EC:2.7.11.-] GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007010//cytoskeleton organization;GO:0007266//Rho protein signal transduction;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0048675//axon extension;GO:0007420//brain development;GO:0006917//induction of apoptosis;GO:0006935//chemotaxis;GO:0007010//cytoskeleton organization;GO:0007266//Rho protein signal transduction;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0048675//axon extension;GO:0007420//brain development;GO:0006917//induction of apoptosis;GO:0006935//chemotaxis;GO:0048675//axon extension;GO:0007420//brain development;GO:0007010//cytoskeleton organization;GO:0006935//chemotaxis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0048675//axon extension;GO:0007420//brain development;GO:0007010//cytoskeleton organization;GO:0006935//chemotaxis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0048675//axon extension;GO:0007420//brain development;GO:0007010//cytoskeleton organization;GO:0006935//chemotaxis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0048675//axon extension;GO:0007420//brain development;GO:0007010//cytoskeleton organization;GO:0006935//chemotaxis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction 32143 4054.00 7.585 8.005 0.0777522222692234 Up 0.125875049531106 CG2025 CG2025 K01411|1|0.0|2114|dme:Dmel_CG2025|nardilysin [EC:3.4.24.61] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835719 371.00 0.49 0.525 0.0995356735509144 Up 0.0546823405098402 34388 2080.00 27.305 28.99 0.0863901765871334 Up 0.203572843745872 CG4972 CG4972 - - - - 31524 1668.07 187.22 83.59 -1.16333229485422 Down 0.74408928807291 CG3011 CG3011, isoform C K00600|1|0.0|981|dya:Dyak_GE15684|glycine hydroxymethyltransferase [EC:2.1.2.1] - - - 19835592 1161.00 0.105 0.125 0.251538766995964 Up 0.0524039096552635 5740789 566.00 71.73 98.525 0.457913213592412 Up 0.614218729362039 246435 1648.00 0.09 0.145 0.68805599368526 Up 0.080537577598732 Obp50b Odorant-binding protein 50b - - GO:0005488//binding GO:0051234//establishment of localization 32757 2931.02 1.08 1.275 0.239465934695389 Up 0.111114780081891 unc-4 unc-4, isoform D K09328|1|1e-121|438|dme:Dmel_CG6269|homeobox protein Unc-4 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 19836111 531.00 0.08 0.19 1.24792751344359 Up 0.113789459780742 44432 2488.00 7.595 5.565 -0.448668277160124 Down 0.404603090740985 ird5 immune response deficient 5 K07209|1|0.0|1486|dme:Dmel_CG4201|inhibitor of nuclear factor kappa-B kinase beta subunit [EC:2.7.11.10] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 40650 1868.89 1.53 1.72 0.168876912009446 Up 0.105237088891824 Orco odorant receptor co-receptor, isoform B K08471|1|0.0|929|dme:Dmel_CG10609|gustatory receptor GO:0043005//neuron projection;GO:0031224//intrinsic to membrane;GO:0043005//neuron projection;GO:0031224//intrinsic to membrane GO:0042802//identical protein binding;GO:0004930//G-protein coupled receptor activity;GO:0042802//identical protein binding;GO:0004930//G-protein coupled receptor activity GO:0010033//response to organic substance;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007635//chemosensory behavior;GO:0010033//response to organic substance;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007635//chemosensory behavior 34875 726.00 16.45 16.12 -0.0292358400946363 Down 0.0886276581693303 NC2beta negative cofactor 2beta K08065|1|3e-13|75.1|tca:658226|nuclear transcription factor Y, beta GO:0017053//transcriptional repressor complex GO:0016564//transcription repressor activity;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter 326216 903.00 107.3 116.09 0.113593627618431 Up 0.275062739400343 Atox1 Atox1, isoform B K04569|1|5e-06|51.6|cin:100184995|copper chaperone for superoxide dismutase - GO:0005507//copper ion binding GO:0006950//response to stress;GO:0030001//metal ion transport 41083 1262.00 4.255 4.95 0.218269393281009 Up 0.212356359793951 CG11986 CG11986 - - - - 319023 863.00 1.085 1.92 0.823411268276677 Up 0.30653150178312 CG31913 CG31913 - - - - 2768672 576.00 0.285 0.24 -0.247927513443585 Down 0.0625742966583014 CG33333 CG33333 - - - - 34828 1181.54 231.99 226.89 -0.0320695941301367 Down 0.114912164839519 CG15293 CG15293, isoform C - - - - 36569 807.18 161.845 161.36 -0.00432980690291914 Down 0.0470545502575618 CG8331 CG8331, isoform D K11449|1|9e-16|84.0|cfa:474695|jumonji domain-containing protein 1 [EC:1.14.11.-];K00939|2|9e-08|57.4|bmy:Bm1_13790|adenylate kinase [EC:2.7.4.3] - - - 41449 1074.53 4.465 2.795 -0.675811892278033 Down 0.40315017831198 CG12201 glutamate carrier 2, isoform D K03454|1|6e-26|118|mdo:100027250|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0051183//vitamin transporter activity GO:0006810//transport 35016 3237.00 6.935 6.805 -0.0273007208196082 Down 0.0667349095231806 Cas CAS/CSE1 segregation protein - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0022892;GO:0005049//nuclear export signal receptor activity GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0007420//brain development;GO:0014016//neuroblast differentiation;GO:0001709//cell fate determination;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0050793//regulation of developmental process 34805 2008.41 45.72 32.055 -0.512275994833511 Down 0.607086250165104 Ance angiotensin converting enzyme, isoform C K01283|1|0.0|1226|dme:Dmel_CG8827|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0044421//extracellular region part;GO:0044464//cell part;GO:0044421//extracellular region part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0009608//response to symbiont;GO:0006997//nucleus organization;GO:0009653//anatomical structure morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0019538//protein metabolic process;GO:0009608//response to symbiont;GO:0006997//nucleus organization;GO:0009653//anatomical structure morphogenesis;GO:0003006//developmental process involved in reproduction 32516 1029.56 95.275 97.365 0.0313055538595546 Up 0.11190727777044 CG8206 CG8206, isoform B - - - - 19835319 315.00 0.01 0.195 4.28540221886225 Up 0.201558578787479 35314 6457.14 17.385 17.79 0.0332234435395316 Up 0.0926231673490952 CG31688 CG31688, isoform G - - - - 59167 788.00 6.56 7.715 0.233970341952651 Up 0.269152027473253 OS9 Olfactory-specific 9 - GO:0043231//intracellular membrane-bounded organelle - - 40672 1414.30 33.45 35.185 0.0729543021489668 Up 0.177750627394003 CG12746 CG12746, isoform E K01080|1|0.0|696|dme:Dmel_CG12746|phosphatidate phosphatase [EC:3.1.3.4] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 14462442 384.00 0.01 0.255 4.6724253419715 Up 0.24085325584467 CG44227 CG44227 - - - - 318150 884.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 CG32679 CG32679 K00747|1|9e-09|60.5|tca:656110|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226];K02330|2|1e-08|60.1|tca:656359|DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-] - - - 32869 1894.00 9.02 7.67 -0.233900855752448 Down 0.287874785365209 CG6961 CG6961 K12881|1|2e-06|54.3|dgr:Dgri_GH18594|THO complex subunit 4 - GO:0005488//binding - 34462 2737.00 0.915 1.32 0.528694281074411 Up 0.193501518953903 CG17098 CG17098 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 246603 1847.44 0.35 0.73 1.06054154193505 Up 0.216186765288601 CG30416 CG30416, isoform C - - - - 36816 1317.00 1.305 1.45 0.15200309344505 Up 0.0925571258750495 CG7755 CG7755 K00030|1|2e-34|146|ame:410396|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] - GO:0046872//metal ion binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding GO:0008152//metabolic process 36022 1053.00 13.195 14.135 0.0992805325049068 Up 0.183859463743231 Ntmt N-terminal methyltransferase - - GO:0016741 - 19835037 331.00 0.16 0.01 -4 Down 0.178939373926826 42064 2476.00 28.75 31.47 0.130415222579324 Up 0.277043983621714 GckIII germinal centre kinase III K08839|1|8e-123|441|nve:NEMVE_v1g135318|serine/threonine kinase 25 [EC:2.7.11.22];K08838|2|2e-120|433|spu:591674|serine/threonine kinase 24 [EC:2.7.11.1] - - - 35089 1517.00 5.45 6.44 0.240804458450328 Up 0.254061550653811 CG7200 CG7200, isoform B K10276|1|2e-06|54.3|smm:Smp_127230|F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] - - - 38182 1487.00 12.195 12.485 0.0339060631320282 Up 0.0854246466781138 Pex10 peroxin 10, isoform B K13346|1|1e-172|606|dme:Dmel_CG7864|peroxin-10 GO:0044439 GO:0046914//transition metal ion binding GO:0006996//organelle organization 8674033 2326.00 12.27 9.775 -0.32796664146819 Down 0.404371945581825 CG42456 CG42456 K10524|1|1e-14|82.0|ame:100187709|nicotinamide riboside kinase 1 [EC:2.7.1.-];K09658|3|1e-14|82.0|aga:AgaP_AGAP006740|dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit GO:0031227//intrinsic to endoplasmic reticulum membrane - GO:0009058//biosynthetic process 40302 3368.52 17.375 16.98 -0.0331765189451939 Down 0.0926231673490952 CG3680 CG3680, isoform D K13239|1|2e-15|85.5|hmg:100214797|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8];K00653|2|2e-14|81.6|mdo:100028261|histone acetyltransferase [EC:2.3.1.48] - - - 31382 1117.23 65.17 67.68 0.0545215735035522 Up 0.151697265882974 CHOp24 CHOp24, isoform B K01529|1|3e-61|235|mcc:709884| [EC:3.6.1.-];K05409|2|7e-20|98.2|ptr:471605|TRIF-related adaptor molecule GO:0031224//intrinsic to membrane - GO:0051234//establishment of localization 12798020 833.00 0.145 0.01 -3.85798099512757 Down 0.168967111345925 35452 1272.09 55.955 61.365 0.133148985335156 Up 0.298936732267864 CG3262 CG3262, isoform F K03593|1|6e-148|523|dse:Dsec_GM18803|ATP-binding protein involved in chromosome partitioning - GO:0032559 - 36005 4116.00 10.615 11.06 0.0592470143293294 Up 0.119105798441421 CG1688 CG1688 K05323|1|3e-10|68.6|cel:C52B9.6|potassium channel subfamily K, invertebrate;K04925|3|7e-09|63.9|gga:421423|potassium channel subfamily K member 17 - - - 37217 2043.03 114.655 92.13 -0.315556352758178 Down 0.538304054946506 CG7461 CG7461, isoform C K09479|1|0.0|1231|dme:Dmel_CG7461|very long chain acyl-CoA dehydrogenase [EC:1.3.99.-] - - - 38428 1478.00 2.505 2.615 0.062000343051733 Up 0.0690463611147801 CycJ cyclin J, isoform B K06627|1|8e-12|61.2|dpo:Dpse_GA19247|cyclin A GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity GO:0000087//M phase of mitotic cell cycle;GO:0000087//M phase of mitotic cell cycle 19835368 367.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 3771879 1023.00 0.07 0.025 -1.48542682717024 Down 0.0803064324395721 His1:CG33810 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 40769 1518.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 Osi13 osiris 13 - - - - 36960 1930.00 1.505 1.43 -0.0737483399813123 Down 0.0606590939109761 mthl4 methuselah-like 4 K04599|1|0.0|1009|dme:Dmel_CG6536|G protein-coupled receptor Mth (Methuselah protein) - - - 35146 2145.59 32.21 25.22 -0.352940385054595 Down 0.510368511425175 CG10602 CG10602, isoform E K01254|1|0.0|1232|dme:Dmel_CG10602|leukotriene-A4 hydrolase [EC:3.3.2.6] - GO:0016803;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016803;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016803;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0006691//leukotriene metabolic process;GO:0019538//protein metabolic process;GO:0006691//leukotriene metabolic process;GO:0019538//protein metabolic process;GO:0006691//leukotriene metabolic process 31022 1100.00 563.195 567.05 0.00984142544201573 Up 0.0706973979659226 RpL22 ribosomal protein L22 K02891|1|2e-39|162|dya:Dyak_GE16569|large subunit ribosomal protein L22e - - - 5740855 569.00 25.755 27.445 0.0916907992512674 Up 0.203572843745872 41284 1104.00 0.285 1.205 2.07999932206522 Up 0.370822876766609 CG4073 CG4073 - - - - 40133 7600.00 7.725 8.36 0.113968009289146 Up 0.164938581429138 ash1 absent, small, or homeotic discs 1, isoform C K06101|1|0.0|3517|dme:Dmel_CG8887|histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0016279//protein-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 31310 7250.20 4.115 3.82 -0.107319792385877 Down 0.117487782327302 dm diminutive, isoform B K04377|1|6e-08|60.5|bfo:BRAFLDRAFT_60197|Myc proto-oncogene protein - - - 42450 1858.00 93.21 11.67 -2.99768018113565 Down 0.817758552370889 Cpr92F cuticular protein 92F - - - - 14462604 1494.00 54.725 52.39 -0.0629085873992489 Down 0.169165235768062 41287 1708.00 0.23 0.495 1.1057946640226 Up 0.179434684982169 CG14691 CG14691, isoform C K06258|1|4e-52|206|aag:AaeL_AAEL005849|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 38898 1956.25 24.415 22.225 -0.135584358920331 Down 0.274798573504161 Arp3 Actin-related protein 3, isoform B K05692|1|5e-62|239|smm:Smp_046590|actin beta/gamma 1 GO:0015629//actin cytoskeleton;GO:0031252//cell leading edge GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0032559 GO:0006909//phagocytosis;GO:0007409//axonogenesis;GO:0008064//regulation of actin polymerization or depolymerization;GO:0000768//syncytium formation by plasma membrane fusion;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007300//ovarian nurse cell to oocyte transport 19835938 713.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 37235 714.67 839.63 746.57 -0.169476178204771 Down 0.38947959318452 RpL11 ribosomal protein L11, isoform B K02868|1|1e-103|375|dya:Dyak_GE12050|large subunit ribosomal protein L11e - - - 36990 3169.00 6.125 4.925 -0.314586119546194 Down 0.301512349755647 POSH plenty of SH3s K12171|1|5e-62|239|oaa:100077176|E3 ubiquitin-protein ligase SH3RF1 [EC:6.3.2.19] - - - 36976 692.00 11.26 10.475 -0.104256583493516 Down 0.174283450006604 CG4866 CG4866 K02997|1|1e-06|53.1|smm:Smp_180000|small subunit ribosomal protein S9e - - - 40913 5752.73 2.68 1.34 -1 Down 0.396612072381456 Nlg1 neuroligin 1, isoform E K07378|1|1e-107|392|tca:659852|neuroligin - GO:0005515//protein binding;GO:0003824//catalytic activity - 19836257 665.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 34080 521.00 27.52 31.275 0.184529414351084 Up 0.345099722625809 SmE small ribonucleoprotein particle protein SmE K11097|1|3e-48|190|dme:Dmel_CG18591|small nuclear ribonucleoprotein E GO:0030532//small nuclear ribonucleoprotein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0000398//mRNA splicing, via spliceosome 39739 1004.00 32.02 29.265 -0.129797029186075 Down 0.277638356888126 CG17026 CG17026 K01092|1|8e-165|579|dme:Dmel_CG17026|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] - GO:0004437//inositol or phosphatidylinositol phosphatase activity GO:0006796//phosphate-containing compound metabolic process 19835446 566.00 0.075 0.085 0.180572245641821 Up 0.045667679302602 19835962 1524.00 7.615 6.26 -0.282681379554674 Down 0.3072249372606 42117 593.00 1.185 1.815 0.615082489097492 Up 0.251287808743891 Edg91 Ecdysone-dependent gene 91, isoform B - - - - 39281 1667.91 1.995 2.595 0.379345792135535 Up 0.225894861973319 CG6140 CG6140, isoform B K01679|1|0.0|910|dme:Dmel_CG6140|fumarate hydratase, class II [EC:4.2.1.2] GO:0043234//protein complex;GO:0044424//intracellular part GO:0016836//hydro-lyase activity GO:0009060//aerobic respiration;GO:0043648//dicarboxylic acid metabolic process 35875 2804.00 7.545 8.205 0.120982432987029 Up 0.173226786421873 CG8272 CG8272, isoform B K10275|1|0.0|1323|dme:Dmel_CG8272|F-box and leucine-rich repeat protein 9 - GO:0005488//binding - 37797 1299.94 1.54 1.405 -0.132360220473975 Down 0.0871087042662792 CG13562 CG13562, isoform C - - - - 31804 2015.38 26.245 20.035 -0.389520087779979 Down 0.519317131158367 CG11284 CG11284, isoform E K01672|1|5e-148|525|dsi:Dsim_GD16911|carbonic anhydrase [EC:4.2.1.1] - - - 3772658 1801.57 15.51 11.725 -0.403610763633352 Down 0.475069343547748 CG33722 CG33722, isoform E K14011|1|4e-13|76.3|xtr:448295|UBX domain-containing protein 6 GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding;GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019798;GO:0004871//signal transducer activity GO:0023060;GO:0019471;GO:0023060 50203 624.00 0.39 0.01 -5.28540221886225 Down 0.314984810460969 CG15127 CG15127 - - - - 33260 1650.91 634.215 635.41 0.00271579573963356 Up 0.0473847576277902 CG3662 CG3662, isoform D - - - - 37874 6876.22 5.595 7.71 0.46259272893864 Up 0.413188482366926 CG3363 over compensating males, isoform C - - - - 2768934 595.00 0.14 0.08 -0.807354922057604 Down 0.0821225729758288 CheB38a chemosensory protein B 38a - GO:0044421//extracellular region part - GO:0009593//detection of chemical stimulus 40287 2100.00 8.98 8.21 -0.129333222963342 Down 0.190991942940166 kni knirps, isoform B K08706|1|2e-167|589|dme:Dmel_CG4717|nuclear receptor subfamily 0 group A GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0004872//receptor activity;GO:0005488//binding;GO:0016564//transcription repressor activity GO:0009888//tissue development;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0035150//regulation of tube size;GO:0048513//organ development;GO:0007067//mitosis;GO:0008595//anterior/posterior axis specification, embryo;GO:0001709//cell fate determination 42389 3509.00 7.335 8.375 0.191292224559107 Up 0.24362699775459 psidin phagocyte signaling impaired - GO:0000323//lytic vacuole - GO:0006909//phagocytosis;GO:0006952//defense response;GO:0006955//immune response 41467 902.00 1.17 2.115 0.854149133536545 Up 0.324362699775459 CG14739 CG14739 K10576|1|6e-105|380|dme:Dmel_CG14739|ubiquitin-conjugating enzyme E2 H [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation;GO:0060255 40899 2646.00 59.84 48.905 -0.291128202758828 Down 0.492999603751156 alpha-Est8 alpha-Esterase-8 K01066|1|0.0|1198|dme:Dmel_CG1121|esterase / lipase [EC:3.1.1.-];K01044|3|6e-159|561|dme:Dmel_CG2505|carboxylesterase [EC:3.1.1.1];K01050|5|4e-154|545|dpo:Dpse_GA10907|cholinesterase [EC:3.1.1.8] - GO:0004091//carboxylesterase activity - 40760 1846.00 0.315 0.37 0.232173442129033 Up 0.0666688680491349 Osi6 osiris 6, isoform B - - - - 43150 1013.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 E(spl)mdelta-HLH enhancer of split mdelta, helix-loop-helix K09090|1|4e-96|351|dme:Dmel_CG8328|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation 5740359 1767.00 0.045 0.03 -0.584962500721156 Down 0.047450799101836 spok spookier K00517|1|0.0|648|dme:Dmel_CG10594| [EC:1.14.-.-];K07419|2|3e-40|166|gga:423065|cytochrome P450, family 2, subfamily R;K00512|3|1e-38|160|dre:399692|cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase) [EC:1.14.99.9];K07410|4|2e-38|160|bta:511470|cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008205//ecdysone metabolic process;GO:0048565//digestive tract development;GO:0007292//female gamete generation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development 19835074 401.00 4.41 3.48 -0.341691349708792 Down 0.273642847708361 246583 966.00 0.05 0.095 0.925999418556223 Up 0.0768722757891956 CG30383 CG30383 - - - - 39385 2204.63 42.285 36.15 -0.226150331453097 Down 0.416325452384097 RhoGAP68F Rho GTPase activating protein at 68F, isoform E K05732|1|8e-21|102|mdo:100016706|glucocorticoid receptor DNA-binding factor 1 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0010004//gastrulation involving germ band extension;GO:0023060 32557 2575.00 9.885 12.895 0.383498902060006 Up 0.443435477479857 CG8924 CG8924 K02174|1|4e-28|127|dme:Dmel_CG11491|broad;K09237|2|9e-28|125|api:100161247|Cys2His2 zinc finger developmental/cell cycle regulator, other - GO:0003676//nucleic acid binding - 2768940 2420.55 114.51 101.415 -0.175202539403526 Down 0.387234183066966 Pp2A-29B protein phosphatase 2A at 29B, isoform E K03456|1|0.0|1102|dse:Dsec_GM16909|protein phosphatase 2 (formerly 2A), regulatory subunit A GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity;GO:0046983//protein dimerization activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0046983//protein dimerization activity;GO:0019888//protein phosphatase regulator activity GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0007243//intracellular protein kinase cascade;GO:0010467//gene expression;GO:0040007//growth;GO:0007051//spindle organization;GO:0090304;GO:0016310//phosphorylation;GO:0034645//cellular macromolecule biosynthetic process;GO:0065003;GO:0012502//induction of programmed cell death;GO:0006464//cellular protein modification process;GO:0035466;GO:0060255;GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0007243//intracellular protein kinase cascade;GO:0010467//gene expression;GO:0040007//growth;GO:0007051//spindle organization;GO:0090304;GO:0016310//phosphorylation;GO:0034645//cellular macromolecule biosynthetic process;GO:0065003;GO:0012502//induction of programmed cell death;GO:0006464//cellular protein modification process;GO:0035466;GO:0060255 37857 3873.85 12.8 14.265 0.156335936694357 Up 0.261326112798838 snama something that sticks like glue, isoform B K13171|1|9e-08|60.1|gga:428216|serine/arginine repetitive matrix protein 1;K13172|3|2e-07|58.9|cin:100187419|serine/arginine repetitive matrix protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 37818 1719.82 11.94 13.465 0.173411393236867 Up 0.271067230220579 CG3065 CG3065, isoform C K09200|1|0.0|719|dme:Dmel_CG3065|transcription factor Sp, invertebrate GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 19835816 549.00 0.155 0.105 -0.561878887608115 Down 0.0745938449346189 33613 6338.12 7.96 9.87 0.310281653912749 Up 0.362435609562805 fred friend of echinoid, isoform H K06768|1|4e-30|134|dpo:Dpse_GA14672|Down syndrome cell adhesion molecule like 1 GO:0044464//cell part;GO:0044464//cell part - - 318597 981.00 1.77 2.345 0.405838562432379 Up 0.222130497952714 CG31115 CG31115 K00772|1|9e-85|313|dwi:Dwil_GK15951|5'-methylthioadenosine phosphorylase [EC:2.4.2.28] - GO:0016763//transferase activity, transferring pentosyl groups GO:0055086//nucleobase-containing small molecule metabolic process;GO:0006796//phosphate-containing compound metabolic process 36904 1253.00 1.435 1.835 0.354729326167525 Up 0.180293224144763 CG9010 CG9010 K00134|1|0.0|664|dme:Dmel_CG9010|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] - - - 36554 2704.66 35.09 32.75 -0.0995650410899918 Down 0.229560163782856 RN-tre related to the N terminus of tre oncogene, isoform F K11837|1|1e-43|178|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K13136|2|2e-06|54.7|nvi:100114269|gem associated protein 8 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 40406 1280.00 258.03 90.075 -1.51834015936868 Down 0.769713380002642 CG32444 CG32444 K01785|1|0.0|765|dme:Dmel_CG32444|aldose 1-epimerase [EC:5.1.3.3] - GO:0005488//binding;GO:0003824//catalytic activity GO:0005996//monosaccharide metabolic process 19835304 807.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 36124 858.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 CG12934 CG12934, isoform B - - - - 43769 6809.62 50.385 65.6 0.380701518549791 Up 0.56359793950601 pan pangolin, isoform S K04491|1|2e-45|184|hsa:6934|transcription factor 7-like 2 - - - 43065 1367.00 16.905 36.65 1.1163631821278 Up 0.705917316074495 CG10560 CG10560 - - - - 34446 764.99 12.07 14.9 0.303886654594502 Up 0.405956940958922 CG6094 CG6094, isoform B - - GO:0008079//translation termination factor activity GO:0006412//translation 37602 4033.00 13.545 10.115 -0.421264073643731 Down 0.469422797516841 ppa partner of paired, isoform C K10280|1|0.0|927|dse:Dsec_GM15616|F-box and leucine-rich repeat protein 14 GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding GO:0019941//modification-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation 42079 1415.12 8.535 10.91 0.354188043295869 Up 0.403645489367323 CG5292 CG5292, isoform B K01500|1|8e-30|131|dre:100034610| [EC:3.5.4.-] - - - 43728 2644.97 6.645 6.75 0.0226183026620187 Up 0.0598335754854048 pasha partner of drosha, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0007444//imaginal disc development 39721 1585.00 3.235 3.605 0.156233547248315 Up 0.143673226786422 CkIIalpha-i1 CKII-alpha subunit interactor-1 K10498|1|1e-12|75.1|ecb:100072181|zinc finger and BTB domain-containing protein 11 GO:0044464//cell part GO:0046914//transition metal ion binding - 32339 1493.47 86.675 79.225 -0.1296601768206 Down 0.305805045568617 Yp3 yolk protein 3, isoform B K01059|1|1e-29|131|dpo:Dpse_GA19044|lipoprotein lipase [EC:3.1.1.34];K13618|3|1e-14|81.6|ssc:100154368|phospholipase A1 member A [EC:3.1.1.-] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton - GO:0007275//multicellular organismal development;GO:0007028//cytoplasm organization;GO:0003006//developmental process involved in reproduction;GO:0044238//primary metabolic process 4379905 1275.00 0.74 0.62 -0.255257055242075 Down 0.0930524369303923 36307 1652.16 907.475 1009.03 0.1530392645961 Up 0.358440100383041 Oda ornithine decarboxylase antizyme, isoform C - - GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity GO:0048869//cellular developmental process;GO:0048869//cellular developmental process;GO:0048869//cellular developmental process 38499 3654.02 0.02 0.01 -1 Down 0.0497292299564126 mas masquerade, isoform C K01310|1|1e-40|169|xla:379495|chymotrypsin [EC:3.4.21.1];K08664|3|4e-40|167|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-];K01316|5|2e-39|164|dre:100148042|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32544 4578.83 89.74 96.47 0.104329182405685 Up 0.252971866332057 Gbeta13F G protein beta-subunit 13F, isoform G K04536|1|0.0|700|dya:Dyak_GE17230|guanine nucleotide binding protein (G protein), beta 1 GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0017111//nucleoside-triphosphatase activity GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway 40023 1995.35 0.495 0.77 0.637429920615292 Up 0.163386606789064 CG4174 CG4174, isoform F K00472|1|0.0|792|dse:Dsec_GM14934|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0019471;GO:0019471;GO:0019471 37312 418.00 0.51 0.57 0.160464672193246 Up 0.0673292827895919 CG13426 CG13426 K07342|1|3e-16|83.2|bmy:Bm1_05280|protein transport protein SEC61 subunit gamma and related proteins - - - 49892 680.11 162.255 198.375 0.289967286505941 Up 0.51935015189539 Fis1 Fis1, isoform G - - - - 32127 2494.00 0.915 0.895 -0.0318840610197861 Down 0.0445449742438251 CG15221 CG15221 K06258|1|3e-50|200|tca:660155|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 - - GO:0006810//transport 33781 1796.69 33.12 31.71 -0.0627647953954859 Down 0.159589222031436 Hel25E helicase at 25E, isoform D K12812|1|0.0|754|dya:Dyak_GE18993|ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0030529//ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0030529//ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0030529//ribonucleoprotein complex GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus;GO:0000278//mitotic cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus;GO:0000278//mitotic cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus 2768716 5700.48 25.82 34.77 0.429354066420437 Up 0.559734513274336 mim missing-in-metastasis, isoform N K05627|1|3e-10|69.3|xtr:100158528|BAI1-associated protein 2 GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding GO:0030035//microspike assembly;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0045806//negative regulation of endocytosis;GO:0030035//microspike assembly;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0045806//negative regulation of endocytosis;GO:0030035//microspike assembly;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0045806//negative regulation of endocytosis;GO:0030035//microspike assembly;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0045806//negative regulation of endocytosis;GO:0030035//microspike assembly;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0045806//negative regulation of endocytosis;GO:0030035//microspike assembly;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0045806//negative regulation of endocytosis 44052 1600.00 16.815 15.485 -0.11887739585192 Down 0.223946638488971 Shc SHC-adaptor protein K06279|1|0.0|761|dsi:Dsim_GD14181|src homology 2 domain-containing transforming protein C - GO:0005488//binding GO:0007424//open tracheal system development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 32477 413.00 0.72 1.1 0.611434712082347 Up 0.192147668735966 CG15641 CG15641 - - - GO:0051234//establishment of localization 37402 1103.00 21.575 17.11 -0.334520799576904 Down 0.465394267600053 mago mago nashi K12877|1|2e-82|306|dvi:Dvir_GJ20538|protein mago nashi - - - 47408 851.99 45.37 47.595 0.0690713622880493 Up 0.183364152687888 Vps28 vacuolar protein sorting 28, isoform B K12184|1|1e-116|419|dsi:Dsim_GD10195|ESCRT-I complex subunit VPS28 - GO:0005488//binding GO:0009790//embryo development;GO:0010796//regulation of multivesicular body size;GO:0007010//cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0001654//eye development 37950 1973.69 10.36 11.46 0.145583041070351 Up 0.230748910315678 ST6Gal sialyltransferase, isoform B K00778|1|0.0|857|dme:Dmel_CG4871|beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.99.1];K00779|3|1e-53|211|dre:403116|beta-galactoside alpha2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.99.-] GO:0031228//intrinsic to Golgi membrane;GO:0031228//intrinsic to Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process 41023 701.78 29.865 29.895 0.00144848911855547 Up 0.0427618544445912 CG11753 CG11753, isoform C - GO:0012505//endomembrane system - - 32194 1180.00 0.04 0.05 0.321928094887362 Up 0.047219653942676 CG15731 CG15731 - - - - 32169 5598.43 38.425 39.48 0.0390767298782642 Up 0.124091929731872 Usp7 Ubiquitin-specific protease 7, isoform C K11838|1|0.0|2277|dme:Dmel_CG1490|ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15] GO:0043231//intracellular membrane-bounded organelle GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process 35928 884.32 27.12 34.96 0.366348006364255 Up 0.52734117025492 GstE13 glutathione S transferase E13, isoform B K00799|1|2e-128|458|dme:Dmel_CG11784|glutathione S-transferase [EC:2.5.1.18] - - - 37047 5271.59 9.77 12.195 0.319859290827799 Up 0.397569673755118 elk Eag-like K[+] channel, isoform B K04911|1|0.0|741|rno:246325|potassium voltage-gated channel Eag-related subfamily H member 8 - - - 43231 2871.27 21.56 25.645 0.250320393224812 Up 0.406419231277242 Rb97D ribonuclear protein at 97D, isoform I K12741|1|3e-62|240|dya:Dyak_GE23791|heterogeneous nuclear ribonucleoprotein A1/A3 - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 19835312 466.00 0.095 0.105 0.144389909335175 Up 0.0448421608770308 34051 2731.12 29.86 15.015 -0.991809690577392 Down 0.681514991414608 CG13796 CG13796, isoform D K05034|1|4e-35|150|tgu:100222137|solute carrier family 6 (neurotransmitter transporter, GABA) member 1;K05042|2|6e-35|149|spu:577731|solute carrier family 6 (neurotransmitter transporter, glycine) member 9 GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 36009 1212.18 248.875 242.49 -0.0374960624517031 Down 0.137069079381852 CG1648 CG1648, isoform C - - - - 43222 5129.00 27.835 25.59 -0.121319935826387 Down 0.253632281072514 Tl toll, isoform D K13023|1|9e-28|127|mcc:707574|carboxypeptidase N regulatory subunit GO:0016021//integral to membrane;GO:0043234//protein complex;GO:0016021//integral to membrane;GO:0043234//protein complex GO:0019904//protein domain specific binding;GO:0004872//receptor activity;GO:0019904//protein domain specific binding;GO:0004872//receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0048534;GO:0051301//cell division;GO:0002783;GO:0023060;GO:0000578//embryonic axis specification;GO:0002780;GO:0007399//nervous system development;GO:0035006//melanization defense response;GO:0002682//regulation of immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0048534;GO:0051301//cell division;GO:0002783;GO:0023060;GO:0000578//embryonic axis specification;GO:0002780;GO:0007399//nervous system development;GO:0035006//melanization defense response;GO:0002682//regulation of immune system process 246644 3102.00 0.17 0.19 0.160464672193246 Up 0.0504556861709153 CG30485 CG30485 - - - - 12798215 2017.19 10.745 10.255 -0.0673379909479317 Down 0.127889314489499 42054 2086.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 CG4009 CG4009, isoform C K00430|1|4e-47|189|cel:F09F3.5|peroxidase [EC:1.11.1.7];K10789|2|2e-45|184|xla:394386|myeloperoxidase [EC:1.11.1.7];K12550|3|4e-45|182|bta:280844|lactoperoxidase [EC:1.11.1.7];K10788|4|3e-44|180|ecb:100070907|eosinophil peroxidase [EC:1.11.1.7] - - - 41911 5818.72 19.935 23.635 0.245621259361319 Up 0.399583938713512 wah non-specific lethal 1, isoform P - - - - 43481 2620.62 46.57 46.16 -0.0127576581748456 Down 0.0659424118346321 alph alphabet, isoform F K01090|1|4e-113|409|dme:Dmel_CG6036|protein phosphatase [EC:3.1.3.16];K04461|2|1e-108|394|rno:24667|protein phosphatase 1B (formerly 2C) [EC:3.1.3.16] GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0043405//regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007472//wing disc morphogenesis;GO:0007049//cell cycle;GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0043405//regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007472//wing disc morphogenesis;GO:0007049//cell cycle;GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0043405//regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007472//wing disc morphogenesis;GO:0007049//cell cycle;GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0043405//regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007472//wing disc morphogenesis;GO:0007049//cell cycle;GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0043405//regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007472//wing disc morphogenesis;GO:0007049//cell cycle 3772047 567.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 CG33767 CG33767 - - - - 34591 1596.00 1.57 1.745 0.152462477318025 Up 0.100250957601374 CG14937 CG14937 - - - - 37393 1160.00 210.1 224.405 0.0950286591890519 Up 0.261392154272883 CG10527 CG10527 - - - - 41303 866.00 3.215 4.335 0.431213255893888 Up 0.31244221371021 CG4565 CG4565 K11433|1|2e-162|570|dme:Dmel_CG4565|histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity GO:0006325//chromatin organization 50192 485.00 0.26 0.29 0.15754127698648 Up 0.0554418174613657 CG15357 CG15357, isoform B - - - - 40887 362.58 9.1 15.7 0.786826108692931 Up 0.607152291639149 Mst84Dc Male-specific RNA 84Dc, isoform B - - - - 42390 1258.00 2.925 2.825 -0.0501857571682166 Down 0.0653810593052437 CG4424 CG4424 K09228|1|2e-36|153|api:100159445|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 14462900 1486.00 0.075 0.035 -1.09953567355091 Down 0.0725795799762251 CG43938 CG43938 - - - - 34911 1013.17 1.555 0.925 -0.74938930961429 Down 0.262580900805706 CG15256 CG15256, isoform C - - - - 45588 5839.67 69.95 77.075 0.139938926942421 Up 0.319772817329283 Pdp1 PAR-domain protein 1, isoform P K09057|1|2e-125|451|dpo:Dpse_GA28498|hepatic leukemia factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent;GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent;GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent;GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent;GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent;GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent;GO:0031667//response to nutrient levels;GO:0006261//DNA-dependent DNA replication;GO:0000087//M phase of mitotic cell cycle;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-dependent 32393 772.00 0.115 0.21 0.868755466721748 Up 0.103255844670453 CG12540 CG12540 - - - - 37373 1152.00 0.27 0.12 -1.16992500144231 Down 0.131851802932241 CG15650 CG15650, isoform B - - - - 34537 1200.82 67.915 84.505 0.315306455923521 Up 0.530973451327434 Ast-C allatostatin C, isoform B - GO:0016020//membrane;GO:0016020//membrane GO:0004872//receptor activity;GO:0005179//hormone activity;GO:0004872//receptor activity;GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0044057;GO:0007186//G-protein coupled receptor signaling pathway;GO:0044057 37014 1402.00 6.535 3.835 -0.7689606582925 Down 0.492636375643904 CG10933 CG10933 K05703|1|2e-06|53.9|mcc:574214|proto-oncogene tyrosine-protein kinase Fyn [EC:2.7.10.2];K05704|2|3e-06|53.5|xla:373647|proto-oncogene tyrosine-protein kinase Src [EC:2.7.10.2] - - - 37102 522.33 211.54 194.335 -0.122384731993631 Down 0.29923391890107 CG15067 CG15067, isoform B - - - - 3772159 2950.40 0.555 0.835 0.589288426123946 Up 0.16160348698983 CG33934 CG33934, isoform E - GO:0016021//integral to membrane;GO:0016020//membrane;GO:0016021//integral to membrane GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0010259//multicellular organismal aging;GO:0006842//tricarboxylic acid transport;GO:0015711//organic anion transport;GO:0030001//metal ion transport;GO:0046942//carboxylic acid transport;GO:0015711//organic anion transport;GO:0030001//metal ion transport;GO:0010259//multicellular organismal aging;GO:0006842//tricarboxylic acid transport;GO:0015711//organic anion transport;GO:0030001//metal ion transport 34450 1693.87 30.825 18.05 -0.772102057515668 Down 0.65222559767534 Lip4 lipase 4, isoform C K01046|1|9e-96|350|dme:Dmel_CG7329|triacylglycerol lipase [EC:3.1.1.3];K01066|3|7e-88|324|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|5|5e-78|291|ecb:100071626|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - - GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 43457 1293.00 0.925 1.045 0.17597767156457 Up 0.0874719323735306 CG14508 CG14508 K00413|1|3e-163|574|dme:Dmel_CG14508|ubiquinol-cytochrome c reductase cytochrome c1 subunit [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain GO:0009055//electron carrier activity;GO:0005506//iron ion binding GO:0022904//respiratory electron transport chain 39687 2046.00 13.07 11.875 -0.138331627689761 Down 0.232234843481707 CG16979 CG16979 K01376|1|2e-77|290|dre:336782| [EC:3.4.22.-] - GO:0008234//cysteine-type peptidase activity;GO:0016788//hydrolase activity, acting on ester bonds - 35347 1243.89 112.24 132.675 0.241309634679078 Up 0.462884691586316 CG9331 CG9331, isoform M K00049|1|1e-136|486|dme:Dmel_CG31674|glyoxylate reductase (NADP+) [EC:1.1.1.79];K00015|2|1e-69|264|hsa:9380|glyoxylate reductase [EC:1.1.1.26];K00058|4|3e-30|133|gga:424381|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] - GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding - 318907 876.74 19.41 14.605 -0.410337759884485 Down 0.5023114515916 CG31710 CG31710, isoform D - - - - 41775 3436.00 1.685 2.94 0.803067563654506 Up 0.370030379078061 CG7886 CG7886 K10165|1|7e-06|53.5|mmu:257632|nucleotide-binding oligomerization domain-containing protein 2 - - - 43569 676.13 30.745 22.945 -0.422172000068215 Down 0.54646017699115 janA janus A, isoform C K01112|1|8e-24|110|dre:445172| [EC:3.1.3.-] - - GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process;GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process;GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process 47729 4447.60 21.17 25.095 0.245378676751919 Up 0.4036124686303 CG16833 CG16833, isoform N K05755|1|3e-21|105|ecb:100058358|actin related protein 2/3 complex, subunit 4;K06047|2|6e-21|103|ssc:445530|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 34499 1128.00 4.04 4.89 0.275479172200439 Up 0.248877294941223 Porin2 Porin2, isoform B K05862|1|2e-160|565|dme:Dmel_CG17137|voltage-dependent anion channel GO:0031224//intrinsic to membrane;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity GO:0006811//ion transport;GO:0046907//intracellular transport;GO:0007165//signal transduction 19835906 458.00 0.46 0.25 -0.879705766282288 Down 0.149616959450535 31036 645.00 0.745 0.98 0.395541323653047 Up 0.140073966450931 CG11663 CG11663, isoform B - - - - 42362 6245.59 7.115 8.38 0.236086487172869 Up 0.28348302734117 CG4562 CG4562, isoform E K05673|1|0.0|2384|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|4|0.0|1550|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0031224//intrinsic to membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0015405;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport;GO:0043623//cellular protein complex assembly;GO:0007017//microtubule-based process;GO:0006810//transport 38821 1848.25 58.535 55.32 -0.081498360982214 Down 0.206709813763043 akirin akirin, isoform F - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0042742//defense response to bacterium;GO:0031349//positive regulation of defense response;GO:0048513//organ development;GO:0042742//defense response to bacterium;GO:0031349//positive regulation of defense response;GO:0048513//organ development;GO:0042742//defense response to bacterium;GO:0031349//positive regulation of defense response;GO:0048513//organ development;GO:0042742//defense response to bacterium;GO:0031349//positive regulation of defense response;GO:0048513//organ development;GO:0042742//defense response to bacterium;GO:0031349//positive regulation of defense response;GO:0048513//organ development 42298 2472.83 20.115 20.37 0.0181742423402574 Up 0.0730088495575221 CG11779 CG11779, isoform E K10836|1|0.0|814|dme:Dmel_CG11779|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane GO:0008320//protein transmembrane transporter activity;GO:0008320//protein transmembrane transporter activity;GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting;GO:0006605//protein targeting;GO:0006605//protein targeting 43295 14788.00 0.21 0.225 0.0995356735509144 Up 0.0473847576277902 CG3339 CG3339 K10408|1|0.0|1912|tad:TRIADDRAFT_23475|dynein heavy chain, axonemal GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 36856 1897.00 20.925 24.33 0.217508697500723 Up 0.372539955091798 CG8311 CG8311 K00902|1|0.0|837|dme:Dmel_CG8311|dolichol kinase [EC:2.7.1.108] - - - 36560 3458.17 21.11 22.465 0.0897524831762822 Up 0.194591203275657 Rcd1 reduction in Cnn dots 1, isoform H - - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0007017//microtubule-based process;GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 41729 1449.00 34.675 21.46 -0.692245806454443 Down 0.640602298243297 CG9631 CG9631 K01362|1|3e-29|129|dpo:Dpse_GA13461| [EC:3.4.21.-];K01316|3|3e-22|106|cfa:487700|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - - - 43490 1348.72 12.875 12.965 0.0100497738953517 Up 0.053625676925109 Bub3 Bub3, isoform B K02180|1|0.0|672|dme:Dmel_CG7581|cell cycle arrest protein BUB3 GO:0015630//microtubule cytoskeleton;GO:0000775//chromosome, centromeric region - GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition 19835547 771.00 1.42 1.47 0.0499252253316823 Up 0.0546493197728173 37149 1454.00 9.405 4.71 -0.997700883910412 Down 0.59140140007925 edl ETS-domain lacking - - - - 42397 1419.00 2.6 1.91 -0.444938984992706 Down 0.248547087570995 CG4973 midlife crisis K13127|1|3e-171|601|dme:Dmel_CG4973|RING finger protein 113A - GO:0046914//transition metal ion binding - 37879 3812.00 9.955 10.73 0.108156855036019 Up 0.179500726456215 CG30419 CG30419 - - - - 19835730 285.00 0.01 0.185 4.20945336562895 Up 0.199412230880993 42979 1764.00 9.185 9.975 0.119037119998359 Up 0.186468101968036 CG31120 phosphatidylinositol glycan anchor biosynthesis, class S ortholog K05291|1|0.0|1050|dme:Dmel_CG31120|phosphatidylinositol glycan, class S - GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019842//vitamin binding GO:0008152//metabolic process 42487 831.00 43.1 20.83 -1.04902502993581 Down 0.707271166292432 CG31189 CG31189 K12347|1|5e-23|107|dan:Dana_GF18523|natural resistance-associated macrophage protein GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding GO:0015031//protein transport 14462557 441.00 0.885 0.01 -6.467605550083 Down 0.475498613129045 CG43647 CG43647 - - - - 33917 1470.00 0.505 0.275 -0.876851769227135 Down 0.156617355699379 osm-6 Osm-6 ortholog - GO:0005875//microtubule associated complex GO:0003774//motor activity GO:0010927;GO:0007275//multicellular organismal development 40684 2351.00 7.71 7.195 -0.0997361731747364 Down 0.146248844274204 Atu another transcription unit - - - - 44910 3236.00 8.67 9.08 0.0666603040690799 Up 0.11943600581165 unc-45 unc-45 K04460|1|2e-14|81.6|tca:660052|protein phosphatase 5 [EC:3.1.3.16];K09553|5|4e-12|74.3|hmg:100203295|stress-induced-phosphoprotein 1 - - - 36244 3260.84 48.465 35.97 -0.43014909185114 Down 0.576244881785761 CG9003 CG9003, isoform G K10268|1|0.0|964|dme:Dmel_CG9003|F-box and leucine-rich repeat protein 2/20 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 3772576 968.00 96.225 51.57 -0.899879720498984 Down 0.710342094835557 Hsp22 heat shock protein 22, isoform B K01010|1|3e-29|130|dme:Dmel_CG12279|thiosulfate sulfurtransferase [EC:2.8.1.1];K09542|2|4e-13|76.6|dme:Dmel_CG4533|crystallin, alpha B;K04455|3|4e-12|73.6|tgu:100225266|heat shock 27kDa protein 1 - - GO:0006457//protein folding;GO:0006950//response to stress;GO:0010259//multicellular organismal aging;GO:0006457//protein folding;GO:0006950//response to stress;GO:0010259//multicellular organismal aging 41383 725.00 0.115 0.62 2.43063435432986 Up 0.283582089552239 CG14708 CG14708 - - - - 43440 3181.76 35.37 28.955 -0.288713722211165 Down 0.467573636243561 CG11880 CG11880, isoform C K12819|1|5e-73|276|spu:593044|pre-mRNA-processing factor SLU7;K06515|2|2e-40|167|mcc:715816|CDW92 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 38595 3233.00 8.96 9.125 0.0263258265971375 Up 0.071060626073174 Aats-ala-m mitochondrial alanyl-tRNA synthetase K01872|1|0.0|2033|dme:Dmel_CG4633|alanyl-tRNA synthetase [EC:6.1.1.7] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 36072 2239.07 105.855 98.17 -0.108735295374912 Down 0.272652225597675 CG12214 mulet, isoform C - - - - 31011 1680.71 13.865 13.355 -0.0540676404043685 Down 0.116695284638753 Dredd death related ced-3/Nedd2-like protein, isoform G K02187|1|9e-21|102|mdo:654275|caspase 3 [EC:3.4.22.56];K04400|2|1e-20|101|xtr:548432|caspase 10 [EC:3.4.22.63] - - - 43598 425.00 1.67 2.855 0.773642642888791 Up 0.358308017434949 CecB cecropin B - GO:0044421//extracellular region part - GO:0042742//defense response to bacterium;GO:0048102//autophagic cell death 31018 1686.00 0.55 0.44 -0.321928094887362 Down 0.0955620129441289 CG13362 CG13362 - - - - 31357 1178.00 8.125 7.695 -0.0784464864749689 Down 0.12696473385286 Xpac xeroderma pigmentosum group A-like K10847|1|2e-165|581|dme:Dmel_CG6358|DNA-repair protein complementing XP-A cells GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding GO:0006281//DNA repair 40985 935.00 0.255 0.19 -0.42449782852791 Down 0.0781931052701096 CG11694 CG11694 - - - - 5740299 1484.00 1.575 1.605 0.0272214687350242 Up 0.0473517368907674 CG34314 CG34314 K02830|1|5e-149|527|dme:Dmel_CG3240|cell cycle checkpoint protein [EC:3.1.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0003677//DNA binding GO:0006259//DNA metabolic process 37692 2848.00 0.905 1.6 0.822082207804157 Up 0.280610223220182 CG9861 CG9861 - - - - 39242 2062.32 3.265 3.895 0.254540336515238 Up 0.206973979659226 CG6279 CG6279, isoform B - GO:0016020//membrane;GO:0016020//membrane GO:0016491//oxidoreductase activity;GO:0016491//oxidoreductase activity - 3355163 1063.67 18.53 19.995 0.109776399782864 Up 0.219587901201955 Rab21 Rab21, isoform D K07890|1|1e-60|231|tca:658631|Ras-related protein Rab-21 - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0006810//transport 12798027 151.00 0.01 0.25 4.64385618977472 Up 0.24085325584467 32063 6316.33 13.755 13.54 -0.0227284007412138 Down 0.0702351076476027 CG42683 CG44422, isoform F K13764|1|3e-26|120|bta:281447|recoverin GO:0043005//neuron projection;GO:0005626//insoluble fraction;GO:0044297//cell body;GO:0016020//membrane;GO:0043005//neuron projection;GO:0005626//insoluble fraction;GO:0044297//cell body;GO:0016020//membrane GO:0046872//metal ion binding;GO:0005216//ion channel activity;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0005216//ion channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport 47901 819.08 57.04 21.13 -1.43268121450895 Down 0.74385814291375 betaTry betaTrypsin, isoform B K01312|1|3e-92|337|dme:Dmel_CG18211|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19834774 1032.00 0.04 0.13 1.70043971814109 Up 0.107350416061286 34823 2036.00 0.245 0.265 0.113210610447991 Up 0.0478470479461102 CG18095 CG18095, isoform C K04309|1|2e-23|110|rno:286994|leucine-rich repeat-containing G protein-coupled receptor 4 - GO:0005488//binding;GO:0005488//binding - 34177 2076.49 4.755 5.105 0.102465620017238 Up 0.123398494254392 fu2 fu2, isoform B K09228|1|8e-42|172|xla:397958|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity - 42265 3588.09 141.775 155.58 0.134053455722742 Up 0.315777308149518 endoA endophilin A, isoform C K11247|1|0.0|667|dya:Dyak_GE25564|endophilin-A GO:0005737//cytoplasm;GO:0005737//cytoplasm GO:0071617//lysophospholipid acyltransferase activity;GO:0005488//binding;GO:0071617//lysophospholipid acyltransferase activity;GO:0005488//binding GO:0065008;GO:0006897//endocytosis;GO:0065008;GO:0006897//endocytosis 32982 1752.63 6.36 6.485 0.028079808967344 Up 0.0651829348831066 CG14231 CG14231, isoform B K01409|1|0.0|784|dme:Dmel_CG14231|O-sialoglycoprotein endopeptidase [EC:3.4.24.57] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38653 1544.26 1.185 1.515 0.354430734574692 Up 0.163287544577995 Tektin-C tektin C, isoform D K04688|1|6e-49|195|cqu:CpipJ_CPIJ003064|p70 ribosomal S6 kinase [EC:2.7.11.1];K11499|3|4e-08|59.7|bta:533089|centromere protein F GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization 40030 2528.14 8.1 7.96 -0.0251534772283384 Down 0.0680227182670717 not non-stop, isoform C K11366|1|0.0|1079|dya:Dyak_GE22066|ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.1.2.15] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process 36395 1973.01 25.115 22.575 -0.153823287303609 Down 0.294148725399551 nemy no extended memory, isoform M K05891|1|5e-142|504|dme:Dmel_CG8776|carbon-monoxide dehydrogenase (cytochrome b-561) [EC:1.2.2.4];K08360|2|4e-27|123|xtr:448092|cytochrome b-561;K08370|5|2e-24|114|oaa:100083870|cytochrome b reductase 1 - - - 34834 1814.00 0.89 1.665 0.903644936104864 Up 0.302040681548012 CG15286 CG15286, isoform B - GO:0044464//cell part - - 39258 4797.69 38.12 49.005 0.362380836249277 Up 0.539261656320169 CG32082 CG32082, isoform E K05627|1|1e-39|166|mmu:108100|BAI1-associated protein 2 - GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding GO:0030035//microspike assembly;GO:0023060;GO:0030035//microspike assembly;GO:0023060;GO:0030035//microspike assembly;GO:0023060 39275 984.00 0.24 0.4 0.736965594166206 Up 0.126634526482631 CG11726 CG11726 K03258|1|6e-09|61.6|dgr:Dgri_GH18041|translation initiation factor eIF-4B - GO:0003723//RNA binding - 41058 4553.17 68.495 57.975 -0.240567763151042 Down 0.447298903711531 CG9821 CG9821, isoform D - - - - 35860 1836.00 0.025 0.03 0.263034405833794 Up 0.0467903843613789 CG14743 CG14743 K13754|1|7e-132|471|dan:Dana_GF12568|solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 GO:0031224//intrinsic to membrane - GO:0006810//transport 40122 1581.14 15.535 3.88 -2.00139368393471 Down 0.722956016378286 Cpr76Bc cuticular protein 76Bc, isoform D - - GO:0005198//structural molecule activity - 19834816 446.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 3885622 634.00 0.01 0.215 4.4262647547021 Up 0.216153744551578 42515 4326.47 47.145 51.34 0.122978523055511 Up 0.276779817725532 SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit, isoform S K07200|1|1e-153|544|api:100164866|5'-AMP-activated protein kinase, regulatory gamma subunit - GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle;GO:0055092//sterol homeostasis;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle 50170 1586.00 26.45 35.205 0.412512620242938 Up 0.550191520274733 Teh3 tipE homolog 3 - GO:0031224//intrinsic to membrane GO:0005198//structural molecule activity GO:0010765//positive regulation of sodium ion transport;GO:0010467//gene expression 39257 1073.00 0.255 0.44 0.787006276665802 Up 0.139545634658566 CG6216 CG6216 - - - - 37811 1071.00 16.955 20.17 0.250500299587531 Up 0.387597411174217 CG16787 CG16787 - - - - 35299 767.40 10.775 11.32 0.0711860888554221 Up 0.133469819046361 mRpS18B mitochondrial ribosomal protein S18B, isoform B - GO:0000314//organellar small ribosomal subunit;GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 36747 4448.12 9.7 8.055 -0.268100158367921 Down 0.325386342623167 bdg bedraggled, isoform D K05040|1|3e-21|105|bfo:BRAFLDRAFT_117178|solute carrier family 6 (neurotransmitter transporter, L-proline) member 7;K05034|4|1e-16|89.7|dre:492490|solute carrier family 6 (neurotransmitter transporter, GABA) member 1 GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006810//transport;GO:0001752//compound eye photoreceptor fate commitment;GO:0006810//transport;GO:0001752//compound eye photoreceptor fate commitment;GO:0006810//transport;GO:0001752//compound eye photoreceptor fate commitment 3772396 4418.65 8.12 11.26 0.471655194895053 Up 0.471569145423326 seq sequoia, isoform B K09237|1|2e-24|115|dwi:Dwil_GK12114|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0030308//negative regulation of cell growth;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 36248 2675.55 126.755 96.68 -0.390753278936984 Down 0.585391625941091 Tret1-1 trehalose transporter 1-1, isoform B K08145|1|2e-83|310|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015151//alpha-glucoside transmembrane transporter activity;GO:0015151//alpha-glucoside transmembrane transporter activity GO:0015766;GO:0000017//alpha-glucoside transport;GO:0000017//alpha-glucoside transport 41620 971.00 0.76 0.935 0.298966946444051 Up 0.115902786950205 CG8508 CG8508 - - - - 50061 835.00 24.475 16.1 -0.604248171489078 Down 0.599788667283054 CG13841 CG13841 - - - - 117342 1116.00 0.04 0.01 -2 Down 0.0694426099590543 CG32395 CG32395 - GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 39681 915.00 0.13 0.16 0.299560281858908 Up 0.0597675340113591 obst-H obstructor-H K01873|1|4e-09|62.0|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K01183|5|9e-06|50.8|dme:Dmel_CG18140|chitinase [EC:3.2.1.14] - GO:0030247//polysaccharide binding GO:0006022 19835743 696.00 0.345 0.01 -5.10852445677817 Down 0.295898824461762 31363 9424.18 15.015 16 0.0916674302175748 Up 0.178146876238278 tyf twenty-four, isoform N - - - - 33882 4455.00 5.86 4.64 -0.336775859294676 Down 0.310956280544182 Pez Pez, isoform B K01104|1|0.0|2060|dme:Dmel_CG9493|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043232 GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process 318096 1279.58 10.975 7.18 -0.612165190599669 Down 0.520010566635847 CG32579 CG32579, isoform C - - - - 40157 1991.00 2.355 0.395 -2.57580250143568 Down 0.523147536653018 Ir76a ionotropic receptor 76a, isoform E - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 12798498 1364.00 0.435 0.17 -1.35548065459839 Down 0.185543521331396 CG43446 CG43446, isoform B - - - - 39466 1427.00 1.11 0.875 -0.343204754517777 Down 0.133469819046361 CG12520 CG12520, isoform C - - GO:0016769//transferase activity, transferring nitrogenous groups;GO:0005488//binding GO:0008152//metabolic process 39776 650.00 25.695 25.53 -0.0092941143980362 Down 0.0592722229560164 PDCD-5 programmed cell death 5 K06875|1|1e-46|185|dme:Dmel_CG13072| - - - 31854 871.74 1.865 8.52 2.1916777999706 Up 0.683496235635979 CG12057 CG12057, isoform B - - - - 19835710 305.00 0.32 0.17 -0.912537158749661 Down 0.126238277638357 39194 2295.00 0.02 0.025 0.321928094887362 Up 0.047219653942676 Ir67b ionotropic receptor 67b - - - GO:0006810//transport 42191 1847.00 0.85 1.205 0.50349840009226 Up 0.181581032888654 CG18599 CG18599 K09311|1|6e-20|99.4|dre:30260|Antp family, other;K09317|2|1e-14|81.6|dre:30537|homeobox protein EMX - - - 140439 1634.00 9.38 6.305 -0.573091552187156 Down 0.48632941487254 Tre1 trapped in endoderm 1, isoform C K04286|1|6e-28|125|dre:30668|melatonin receptor 1B;K04285|2|1e-25|118|mcc:702686|melatonin receptor 1A GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity;GO:0004930//G-protein coupled receptor activity GO:0023060;GO:0008354//germ cell migration;GO:0050909//sensory perception of taste;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction;GO:0007166//cell surface receptor signaling pathway 33924 2052.49 82.055 87.2 0.0877368883390895 Up 0.23134328358209 CG11050 CG11050, isoform C K07023|1|0.0|692|dme:Dmel_CG11050|putative hydrolases of HD superfamily - - - 3772605 654.00 3.835 6.53 0.767856414043497 Up 0.492636375643904 14462453 851.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 41961 1340.26 6.665 7.005 0.071780175341845 Up 0.110718531237617 Fer2 48 related 2, isoform E K09073|1|5e-16|85.5|dre:368662|pancreas-specific transcription factor 1a - - - 45307 3817.00 7.285 7.015 -0.0544858684446135 Down 0.0935807687227579 fz frizzled, isoform C K02378|1|4e-149|529|dre:30369|frizzled 7;K02432|3|4e-148|526|bta:445417|frizzled 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral to membrane;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity GO:0007163//establishment or maintenance of cell polarity;GO:0016055//Wnt receptor signaling pathway;GO:0051017//actin filament bundle assembly;GO:0001752//compound eye photoreceptor fate commitment;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0051301//cell division;GO:0001737//establishment of imaginal disc-derived wing hair orientation;GO:0035151//regulation of tube size, open tracheal system;GO:0023060;GO:0008104//protein localization;GO:0001709//cell fate determination;GO:0030859//polarized epithelial cell differentiation;GO:0048588//developmental cell growth;GO:0007431//salivary gland development 35936 2063.73 0.77 0.76 -0.0188590272513159 Down 0.0413749834896315 CG8046 CG8046, isoform B - GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor GO:0006071//glycerol metabolic process;GO:0006810//transport;GO:0006071//glycerol metabolic process;GO:0006810//transport 37378 973.00 131.32 82.56 -0.669571779149726 Down 0.678113855501255 Pros29 proteasome alpha3 subunit K02728|1|6e-139|493|dme:Dmel_CG9327|20S proteasome subunit alpha 3 [EC:3.4.25.1] - - - 41772 3353.28 29.67 28.68 -0.0489599027783624 Down 0.136177519482235 put punt, isoform C K13597|1|0.0|1051|dme:Dmel_CG7904|activin receptor type-2, invertebrate - - - 2768925 909.00 1.925 1.575 -0.289506617194985 Down 0.160645885616167 CG33308 CG33308 - - - - 36519 3859.00 0.185 0.525 1.50479215203717 Up 0.214271562541276 CG18368 CG18368 K00134|1|2e-11|72.4|dwi:Dwil_GK21310|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12];K01900|4|4e-07|57.8|dwi:Dwil_GK11971|succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity GO:0005975//carbohydrate metabolic process 50024 431.99 77.965 63.965 -0.285543900081887 Down 0.501188746532823 CG11686 CG11686, isoform B - - - - 37029 2201.00 21.53 18.175 -0.244392955360277 Down 0.384823669264298 OstDelta oligosaccharide transferase delta subunit, isoform B K12667|1|0.0|1174|dme:Dmel_CG6370|oligosaccharyltransferase complex subunit delta (ribophorin II) - - - 37663 1670.00 2.555 3.76 0.557409370740016 Up 0.340807026812838 CG3085 CG3085, isoform B K11438|1|6e-07|55.8|dme:Dmel_CG9882|protein arginine N-methyltransferase 7 [EC:2.1.1.-];K10352|2|7e-06|52.4|cel:K12F2.1|myosin heavy chain;K04688|3|7e-06|52.4|aag:AaeL_AAEL000743|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization 37851 1461.47 21.21 21.525 0.021268616753651 Up 0.0771694624224013 yki yorkie, isoform G K10591|1|3e-09|63.2|rno:25489|E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19];K05630|5|2e-08|60.8|dre:564527|atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:6.3.2.19] - GO:0005488//binding;GO:0005488//binding - 12798428 250.00 1.85 2.355 0.348201789096471 Up 0.204431382908467 CG43251 CG43251 - - - - 31276 729.00 96.395 36.35 -1.40700295178877 Down 0.752344472328622 CG14419 CG14419 - - - - 326118 1755.50 15.345 8.43 -0.864164109524402 Down 0.61781798969753 CG31102 CG31102, isoform B - - - - 42553 4624.00 0.815 0.58 -0.490747159103505 Down 0.141658961828028 DNApol-alpha180 DNA polymerase alpha 180kD K02320|1|0.0|2845|dme:Dmel_CG6349|DNA polymerase alpha subunit A [EC:2.7.7.7] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0034061 GO:0006259//DNA metabolic process 43537 525.00 0.16 0.49 1.61470984411521 Up 0.21397437590807 CG15517 CG15517 - - - - 19834968 835.00 0.41 0.59 0.525091044743758 Up 0.126931713115837 318101 677.00 0.18 0.395 1.13385574673479 Up 0.160777968564258 CG32588 CG32588 - - - - 38155 528.00 18.79 1.295 -3.8589410637335 Down 0.808215559371285 msd1 mitotic spindle density 1 - GO:0015630//microtubule cytoskeleton - GO:0000226//microtubule cytoskeleton organization 38070 10237.76 33.38 27.715 -0.268316947075624 Down 0.444591203275657 hipk homeodomain interacting protein kinase, isoform C K08826|1|0.0|1882|dme:Dmel_CG17090|homeodomain interacting protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0032559;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0032559 GO:0001654//eye development;GO:0016055//Wnt receptor signaling pathway;GO:0008593//regulation of Notch signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0031647//regulation of protein stability;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0016055//Wnt receptor signaling pathway;GO:0008593//regulation of Notch signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0031647//regulation of protein stability;GO:0006464//cellular protein modification process 31798 2662.85 31.99 27.19 -0.234544841090914 Down 0.402852991678774 CG12065 CG12065, isoform F - - - GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process 36288 1304.00 18.37 18.575 0.0160105843146089 Up 0.0696077136441685 128up upstream of RpIII128 K06944|1|3e-153|541|mcc:716791| GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding - 40973 2898.00 1.28 1.065 -0.265290379774162 Down 0.122110685510501 Mcm2 minichromosome maintenance 2 K02540|1|0.0|1626|dme:Dmel_CG7538|minichromosome maintenance protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044427//chromosomal part;GO:0032993//protein-DNA complex GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0051276//chromosome organization;GO:0060255;GO:0006270//DNA replication initiation;GO:0010467//gene expression 35921 3791.00 6.705 7.09 0.0805482953350421 Up 0.120657773081495 CG8777 CG8777 K12600|1|0.0|2369|dme:Dmel_CG8777|superkiller protein 3 - - GO:0006402//mRNA catabolic process 2768725 1125.52 0.47 0.895 0.929226925586619 Up 0.223517368907674 CG33474 CG33474, isoform B K13353|1|6e-41|166|dsi:Dsim_GD21009|peroxin-11C GO:0044439 - - 35938 885.00 5.4 5.725 0.0843162859334753 Up 0.11121384229296 CG42382 CG42382 - - GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0044260 36026 1838.00 2.02 1.52 -0.410283969308209 Down 0.208195746929071 CG12923 CG12923, isoform B - - - GO:0006629//lipid metabolic process 39579 714.00 0.255 0.62 1.28177096841538 Up 0.21582353718135 CG13481 CG13481, isoform C K08849|1|1e-06|53.1|gga:415684|mixed lineage kinase domain-like [EC:2.7.11.1] - GO:0046914//transition metal ion binding - 33930 4644.44 25.88 28.345 0.131256651826919 Up 0.27189274864615 Tango1 transport and golgi organization 1, isoform D K10352|1|2e-11|72.8|oaa:100086990|myosin heavy chain;K10421|3|6e-11|70.9|cfa:477461|CAP-Gly domain-containing linker protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - 43256 1970.54 21.41 20.545 -0.059497465217853 Down 0.144564786686039 spz spatzle, isoform L - GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042802//identical protein binding GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0008063//Toll signaling pathway;GO:0006461//protein complex assembly;GO:0042742//defense response to bacterium;GO:0007310//oocyte dorsal/ventral axis specification;GO:0002783 8674067 451.74 1.615 2.545 0.65613149138177 Up 0.307158895786554 CG42560 CG42560, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0030234//enzyme regulator activity GO:0006140 36665 1631.00 11.23 15.555 0.470020467133781 Up 0.509212785629375 Cyp6a21 Cyp6a21 K00517|1|0.0|961|dme:Dmel_CG10247| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 45338 7816.74 20.95 24.22 0.209248621107614 Up 0.361940298507463 na narrow abdomen, isoform G K05315|1|2e-50|202|spu:578128|voltage-dependent calcium channel alpha 1, invertebrate GO:0033267//axon part;GO:0031224//intrinsic to membrane;GO:0044297//cell body;GO:0033267//axon part;GO:0031224//intrinsic to membrane;GO:0044297//cell body GO:0005216//ion channel activity;GO:0005216//ion channel activity GO:0006810//transport;GO:0007626//locomotory behavior;GO:0050789//regulation of biological process;GO:0007622//rhythmic behavior;GO:0006810//transport;GO:0007626//locomotory behavior;GO:0050789//regulation of biological process;GO:0007622//rhythmic behavior 41033 1904.17 33.195 18.72 -0.826385516938763 Down 0.665070664377229 CG8112 CG8112, isoform D - - - - 40264 1100.08 39.47 35.15 -0.167231829933205 Down 0.341962752608638 CG5910 CG5910, isoform B - - - - 39411 546.00 0.7 1.45 1.05062607306997 Up 0.305507858935411 Obp69a Odorant-binding protein 69a - - GO:0008144//drug binding;GO:0005549//odorant binding GO:0051234//establishment of localization 19834765 773.00 0.105 0.12 0.192645077942396 Up 0.0514463082816008 34496 4499.39 45.745 51.04 0.158014265911832 Up 0.337835160480782 CG6700 CG6700, isoform B - - - - 42310 8614.27 56.705 72.815 0.36075972705428 Up 0.554913485669 unc79 unc79, isoform F - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 39867 460.00 0.01 0.345 5.10852445677817 Up 0.295898824461762 CG13031 CG13031 - - - - 36801 3367.00 0.855 1.165 0.446333629768382 Up 0.16520274732532 CG15701 CG15701 K04574|1|1e-07|59.7|gga:417020|neurofilament heavy polypeptide - - - 42258 9780.07 4.77 9.94 1.05925658555677 Up 0.606723022057852 CG18208 CG18208, isoform C K04140|1|2e-48|194|dre:266752|adrenergic receptor alpha-2C;K04138|5|1e-47|192|mcc:695684|adrenergic receptor alpha-2A GO:0031224//intrinsic to membrane GO:0004936//alpha-adrenergic receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 32444 2288.00 21.195 11.03 -0.942291175463713 Down 0.657310791176859 Cyp4s3 Cyp4s3 K00517|1|0.0|941|dme:Dmel_CG9081| [EC:1.14.-.-];K07427|5|3e-95|349|dre:562008|cytochrome P450, family 4, subfamily V GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 39518 2872.81 61.775 56.09 -0.139279522534362 Down 0.314126271298375 stv starvin, isoform G K09558|1|7e-11|69.7|mcc:703953|BCL2-associated athanogene 4 GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band GO:0031072//heat shock protein binding;GO:0031072//heat shock protein binding;GO:0031072//heat shock protein binding;GO:0031072//heat shock protein binding;GO:0031072//heat shock protein binding - 50109 954.38 22.435 22.56 0.00801588372244856 Up 0.0563994188350284 CG13255 CG13255, isoform B - - - - 14462899 479.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 34096 4366.54 47.58 45.37 -0.0686166120743903 Down 0.183331131950865 Cka connector of kinase to AP-1, isoform G K01062|1|1e-20|102|dgr:Dgri_GH22777|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0043410//positive regulation of MAPK cascade;GO:0006909//phagocytosis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001751//compound eye photoreceptor cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0006909//phagocytosis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001751//compound eye photoreceptor cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0006909//phagocytosis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001751//compound eye photoreceptor cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0006909//phagocytosis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001751//compound eye photoreceptor cell differentiation 5740764 838.00 129.965 163.47 0.330902743686539 Up 0.552205785233126 32862 1883.00 0.305 0.365 0.259087221317131 Up 0.0724144762911108 CG12609 CG12609 - - - - 45249 814.18 262.31 256.085 -0.0346500577157332 Down 0.115275392946771 Ef1beta elongation factor 1 beta, isoform C K03232|1|2e-123|441|dme:Dmel_CG6341|elongation factor EF-1 beta subunit GO:0043234//protein complex GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 31321 1829.00 0.085 0.395 2.21631790692676 Up 0.215196143177916 Gas8 growth arrest specific protein 8, isoform D K11498|1|5e-08|60.1|dwi:Dwil_GK14900|centromeric protein E;K08286|3|7e-07|56.2|bta:538392|protein-serine/threonine kinase [EC:2.7.11.-];K10362|4|2e-06|55.1|ecb:100059638|myosin XVIII - - - 34490 3733.01 14.62 16.85 0.204805280116784 Up 0.324626865671642 CG31869 CG31869, isoform C K06236|1|6e-06|53.9|dre:562496|collagen, type I/II/III/V/XI, alpha;K07371|2|7e-06|53.5|tgu:100230399|B-cell linker - - - 43707 3009.40 62.925 63.825 0.0204883212461394 Up 0.0877030775326905 CG1607 CG1607, isoform D K03450|1|0.0|924|dme:Dmel_CG1607|solute carrier family 7 (L-type amino acid transporter), other;K13872|5|2e-129|464|bta:530661|solute carrier family 7 (L-type amino acid transporter), member 6 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0006865//amino acid transport;GO:0006865//amino acid transport 31163 1203.00 19.24 25.185 0.388455931888144 Up 0.515915995245014 CG4406 CG4406 K01567|1|0.0|715|dme:Dmel_CG4406| [EC:3.-.-.-];K05290|2|9e-122|436|bfo:BRAFLDRAFT_66566|phosphatidylinositol glycan, class K [EC:2.6.-.-] - - - 32521 1367.00 0.82 1.415 0.787106238213799 Up 0.25775987320037 CG8260 CG8260, isoform B - - - - 38811 1857.23 32.36 28.885 -0.163891113089852 Down 0.320598335754854 lark lark, isoform E K13187|1|1e-163|576|dme:Dmel_CG8597|RNA-binding protein 4 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding GO:0007563//regulation of eclosion;GO:0000377;GO:0007010//cytoskeleton organization;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0033036;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007563//regulation of eclosion;GO:0000377;GO:0007010//cytoskeleton organization;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0033036;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007563//regulation of eclosion;GO:0000377;GO:0007010//cytoskeleton organization;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0033036;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007563//regulation of eclosion;GO:0000377;GO:0007010//cytoskeleton organization;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0033036;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007563//regulation of eclosion;GO:0000377;GO:0007010//cytoskeleton organization;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0033036;GO:0007300//ovarian nurse cell to oocyte transport 36055 1686.00 1.03 2.04 0.985924814788277 Up 0.343712851670849 sut4 sugar transporter 4 K08145|1|2e-72|273|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity GO:0006810//transport 10178933 577.00 0.84 0.94 0.162271428898877 Up 0.0800752872804121 CG42841 CG42841, isoform B - - - - 36702 2089.00 2.065 2.32 0.167983023708127 Up 0.119270902126535 Hr51 hormone receptor 51 K08546|1|0.0|810|dme:Dmel_CG16801|nuclear receptor subfamily 2 group E member 3 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005506//iron ion binding GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0060560//developmental growth involved in morphogenesis;GO:0006351//transcription, DNA-dependent 40858 1888.04 53.175 32.815 -0.696392695084864 Down 0.662594109100515 gfzf GST-containing FLYWCH zinc-finger protein, isoform E K00799|1|2e-134|480|dme:Dmel_CG33546|glutathione S-transferase [EC:2.5.1.18] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0042277//peptide binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0042277//peptide binding - 31898 825.00 6.755 5.75 -0.232393813493947 Down 0.252773741909919 CG15317 CG15317 - - - - 35715 5355.95 15.455 17 0.13746109216684 Up 0.250825518425571 CG1399 CG1399, isoform G K12800|1|1e-08|63.5|rno:287362|NACHT, LRR and PYD domains-containing protein 3;K12798|2|2e-07|59.7|ptr:468451|NACHT, LRR and PYD domains-containing protein 1;K08727|4|5e-07|58.2|ptr:472336|nucleotide-binding oligomerization domain-containing protein 1 - GO:0004672//protein kinase activity;GO:0032559;GO:0005488//binding;GO:0005488//binding;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0010927;GO:0010927;GO:0010927;GO:0006464//cellular protein modification process;GO:0010927;GO:0006464//cellular protein modification process;GO:0010927 43571 1855.00 0.51 0.75 0.556393348524385 Up 0.14700832122573 Sry-alpha serendipity alpha - GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0008092//cytoskeletal protein binding GO:0007275//multicellular organismal development;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis 19836078 475.00 0.275 0.01 -4.78135971352466 Down 0.252509576013737 43549 1005.00 21.375 17.205 -0.313096527923641 Down 0.44914806498481 eIF2B-alpha eIF2B-alpha K03239|1|1e-171|602|der:Dere_GG11983|translation initiation factor eIF-2B alpha subunit GO:0043234//protein complex GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 40715 2242.09 21.435 21.44 0.000336488640799647 Up 0.0382380134724607 kat-60L1 katanin p60-like 1, isoform H K07767|1|2e-124|446|isc:IscW_ISCW015571|microtubule-severing ATPase [EC:3.6.4.3] GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559;GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0032559 GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process;GO:0042551//neuron maturation;GO:0007017//microtubule-based process 38175 3659.69 50.695 39.705 -0.352522767040581 Down 0.534209483555673 Psa puromycin sensitive aminopeptidase, isoform I K08776|1|0.0|1894|dse:Dsec_GM14417|puromycin-sensitive aminopeptidase [EC:3.4.11.-] - GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 45786 2455.00 13.415 12.21 -0.135783854273118 Down 0.232234843481707 Aats-gln Glutaminyl-tRNA synthetase K01886|1|0.0|1492|dme:Dmel_CG10506|glutaminyl-tRNA synthetase [EC:6.1.1.18] GO:0015630//microtubule cytoskeleton GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 34588 960.52 0.345 0.59 0.774118592583672 Up 0.156122044644036 CG14931 CG14931, isoform C - - - - 41140 1958.00 54.28 49.715 -0.12673951362489 Down 0.294611015717871 Ras85D Ras oncogene at 85D K07827|1|1e-83|310|dya:Dyak_GE24771|GTPase KRas GO:0016020//membrane GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0001883//purine nucleoside binding GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0002164//larval development;GO:0048534;GO:0006605//protein targeting;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0042065;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0022402//cell cycle process;GO:0000578//embryonic axis specification;GO:0045666//positive regulation of neuron differentiation;GO:0060446//branching involved in open tracheal system development;GO:0035264//multicellular organism growth;GO:0002682//regulation of immune system process;GO:0007472//wing disc morphogenesis;GO:0048598//embryonic morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0035556//intracellular signal transduction 43307 1347.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 CG13972 CG13972 - - - - 5740771 1761.00 0.17 0.215 0.338801913451758 Up 0.0665037643640206 CG34235 CG34235 - - - - 40402 1692.92 46.945 57.405 0.290204893674624 Up 0.491744815744287 CG11306 CG11306, isoform B K03844|1|0.0|924|dme:Dmel_CG11306|alpha-1,2-mannosyltransferase [EC:2.4.1.-] - GO:0016740//transferase activity GO:0008152//metabolic process 39076 1733.00 20.53 23.765 0.211104774193734 Up 0.361279883767006 Hsp67Ba heat shock gene 67Ba K04455|1|5e-18|92.8|cin:100177240|heat shock 27kDa protein 1;K09542|3|4e-17|89.7|dme:Dmel_CG4533|crystallin, alpha B - - GO:0006950//response to stress 40043 1640.00 1.9 2.145 0.174978229168598 Up 0.119270902126535 Nufip nufip - GO:0044464//cell part GO:0003723//RNA binding;GO:0046914//transition metal ion binding - 31347 3619.00 8.285 7.985 -0.0532092898102193 Down 0.0974772156914542 CG2938 CG2938, isoform D - - - - 40892 1878.00 0.325 1.115 1.77853208689185 Up 0.338561616695285 wa-cup walker cup - - - GO:0007126//meiosis 42776 1856.00 0.06 0.025 -1.26303440583379 Down 0.0654471007792894 CG10168 CG10168 K00699|1|8e-132|470|dpo:Dpse_GA18421|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 318227 2034.00 0.675 0.185 -1.86736223142188 Down 0.26911900673623 CG32819 CG32819, isoform B K04688|1|2e-19|97.4|aag:AaeL_AAEL000743|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization 34312 2134.00 26.64 26.665 0.00135324561173183 Up 0.0416061286487914 Srp54 Srp54 K13165|1|2e-160|566|dsi:Dsim_GD23635|splicing factor, arginine/serine-rich 12 GO:0005681//spliceosomal complex GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly 14462795 785.00 0.105 0.06 -0.807354922057604 Down 0.07657508915599 CG43814 CG43814 - - - - 44653 6729.18 6.405 5.225 -0.293767533373402 Down 0.292794875181614 wech wech, isoform E K12035|1|0.0|1439|dme:Dmel_CG42396|tripartite motif-containing protein 71 GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 2768685 6987.35 9.19 10.145 0.142632098467624 Up 0.212356359793951 mld molting defective, isoform F K10055|1|6e-15|84.7|cfa:489398|zinc finger and BTB domain-containing protein 16;K09228|3|1e-14|84.0|bta:508931|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0008205//ecdysone metabolic process;GO:0008205//ecdysone metabolic process 35969 1548.95 81.555 84.555 0.0521167393431102 Up 0.153414344208163 prel preli-like, isoform C - GO:0005743//mitochondrial inner membrane - GO:0007005//mitochondrion organization;GO:0048812//neuron projection morphogenesis 32692 1838.00 0.66 0.915 0.471305718925589 Up 0.150211332716946 CG4955 CG4955 - - - - 42019 1671.00 0.115 0.355 1.62618516344767 Up 0.178014793290186 CG12783 CG12783, isoform C K06258|1|2e-29|130|tca:662982|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 - - - 35580 1278.00 0.21 0.04 -2.39231742277876 Down 0.155890899484876 CG9430 Zinc/iron regulated transporter-related protein 42C.2 - GO:0044464//cell part GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport 32446 576.61 934.795 943.065 0.0127071934250818 Up 0.0711596882842425 RpL37a ribosomal protein L37a, isoform B K02922|1|7e-50|197|dme:Dmel_CG9091|large subunit ribosomal protein L37e GO:0015934//large ribosomal subunit GO:0043169//cation binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 53512 1620.00 0.1 0.6 2.58496250072116 Up 0.287379474309867 Ugt36Bb Ugt36Bb K00699|1|0.0|1053|dme:Dmel_CG13271|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 33038 645.00 31.13 28.29 -0.138013400072927 Down 0.290351340641923 Obp19b Odorant-binding protein 19b K10595|1|8e-37|153|dsi:Dsim_GD17489|E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19] - GO:0005506//iron ion binding GO:0007600//sensory perception;GO:0051234//establishment of localization 33539 2564.60 0.14 0.12 -0.222392421336448 Down 0.0521727644961036 CG3332 CG3332, isoform D - - - - 53442 3460.00 21.15 21.13 -0.0013648960723715 Down 0.0416061286487914 Spt5 Spt5 K13110|1|0.0|716|bmy:Bm1_19900|microfibrillar-associated protein 1 GO:0000178//exosome (RNase complex);GO:0005700//polytene chromosome GO:0030528//transcription regulator activity;GO:0016740//transferase activity GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0006368//transcription elongation from RNA polymerase II promoter 41071 1408.00 16.205 16.535 0.0290840248732746 Up 0.0886276581693303 RagA Ras-related GTP binding A/B ortholog - GO:0043231//intracellular membrane-bounded organelle GO:0032561//guanyl ribonucleotide binding GO:0016049//cell growth 317852 1057.00 8.365 9.825 0.232091867107616 Up 0.296295073306036 eap ebony activating protein K00142|1|7e-37|154|hsa:60496|aminoadipate-semialdehyde dehydrogenase [EC:1.2.1.31] GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0016780//phosphotransferase activity, for other substituted phosphate groups GO:0006464//cellular protein modification process;GO:0009058//biosynthetic process 41537 1328.00 5.825 6.935 0.25163783278196 Up 0.270538898428213 CG5538 CG5538 - - - - 39428 1583.38 23.075 24.15 0.0656925411899989 Up 0.162792233522652 CG10654 CG10654, isoform B K09228|1|1e-23|110|mcc:713528|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 41231 1245.00 0.22 0.14 -0.652076696579693 Down 0.09047681944261 Fancl fancl, isoform B K10606|1|0.0|763|dme:Dmel_CG12812|E3 ubiquitin-protein ligase FANCL [EC:6.3.2.19] - GO:0005488//binding - 41334 1781.00 15.82 7.33 -1.10986449633898 Down 0.657046625280676 Ugt35a UDP-glycosyltransferase 35a K00699|1|0.0|1018|dme:Dmel_CG6644|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 12798398 161.00 0.37 0.01 -5.20945336562895 Down 0.306333377360983 39226 2565.72 68.785 66.465 -0.0494991620187785 Down 0.150871747457403 Aps Aps, isoform C K07766|1|3e-81|303|dya:Dyak_GE20253|diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - 34211 1005.98 2.37 1.445 -0.713817566397581 Down 0.31244221371021 Tsp29Fa tetraspanin 29Fa, isoform C K06497|1|2e-118|425|dme:Dmel_CG9494|CD63 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 35264 1921.00 3.3 2.335 -0.499043474536154 Down 0.298111213842293 CG10463 CG10463 K05544|1|0.0|1215|dme:Dmel_CG10463|tRNA-dihydrouridine synthase 3 [EC:1.-.-.-] - GO:0030554//adenyl nucleotide binding;GO:0046914//transition metal ion binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0006399//tRNA metabolic process 42646 8072.11 56.31 68.985 0.292891547549059 Up 0.497787610619469 Nrx-1 neurexin 1, isoform I K07377|1|0.0|1817|cqu:CpipJ_CPIJ013638|neurexin GO:0016020//membrane;GO:0045202//synapse;GO:0016020//membrane;GO:0045202//synapse - GO:0043062//extracellular structure organization;GO:0007267//cell-cell signaling;GO:0043062//extracellular structure organization;GO:0007267//cell-cell signaling 42337 1716.00 0.685 1.04 0.602407635180565 Up 0.186269977545899 CG17752 CG17752 K08202|1|2e-48|194|der:Dere_GG11272|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 38328 934.00 1.15 0.71 -0.695742931439693 Down 0.212224276845859 CG14949 CG14949 - - - - 42838 1046.00 74.24 71.55 -0.0532449435135421 Down 0.152522784308546 CG13603 CG13603 - - - - 33830 1236.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 psd palisade, isoform B - - - - 37674 2499.00 0.795 1.13 0.507296007130832 Up 0.173523973055079 Klp59D Kinesin-like protein at 59D K10393|1|0.0|1326|dme:Dmel_CG12192|kinesin family member 2/24 GO:0005874//microtubule;GO:0005819//spindle GO:0003774//motor activity;GO:0032559 GO:0000226//microtubule cytoskeleton organization;GO:0007067//mitosis 14462768 987.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 14462474 281.00 0.01 0.22 4.4594316186373 Up 0.222989037115308 CG44094 CG44094 - - - - 48387 3059.91 31.505 37.505 0.251502132471711 Up 0.431382908466517 l(2)k14710 lethal (2) k14710, isoform B - - - - 40164 2692.62 25.195 27.07 0.103557431245211 Up 0.221404041738212 Deaf1 deformed epidermal autoregulatory factor-1, isoform E K10053|1|2e-07|58.2|gga:395503|runt-related transcription factor 1; translocated to, 1 GO:0005694//chromosome;GO:0005694//chromosome GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0002682//regulation of immune system process;GO:0009790//embryo development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0002682//regulation of immune system process;GO:0009790//embryo development 41197 947.85 29.045 30.665 0.0783031211201142 Up 0.188746532822613 CG9471 CG9471, isoform B K05901|1|1e-29|130|dre:436959|biliverdin reductase / flavin reductase [EC:1.3.1.24 1.5.1.30] - GO:0048037//cofactor binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0008152//metabolic process;GO:0008152//metabolic process 43799 4118.76 42.805 41 -0.0621554161921824 Down 0.164872539955092 Ephrin ephrin, isoform C K05463|1|4e-83|309|aga:AgaP_AGAP009426|ephrin-B - - - 44736 831.00 66.08 65.39 -0.0151436634728261 Down 0.0860850614185709 CG3719 CG3719 K03671|1|2e-20|100|xtr:493523|thioredoxin 1 GO:0043231//intracellular membrane-bounded organelle - GO:0019725//cellular homeostasis 37286 1625.00 0.075 0.16 1.09310940439148 Up 0.0978734645357284 ppk6 pickpocket 6 K04832|1|1e-14|81.3|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal - - - 14462714 854.00 0.235 0.13 -0.854149133536545 Down 0.107416457535332 CG43799 CG43799 - - - - 37347 1251.00 0.04 0.01 -2 Down 0.0694426099590543 Gr57a gustatory receptor 57a K08471|1|0.0|815|dme:Dmel_CG13441|gustatory receptor - - - 32841 2033.57 33.91 28.04 -0.274224435014808 Down 0.4462422401268 Aats-his Histidyl-tRNA synthetase, isoform E K01892|1|0.0|1010|der:Dere_GG19169|histidyl-tRNA synthetase [EC:6.1.1.21] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 34616 6470.00 5.55 6.72 0.275973461541292 Up 0.288469158631621 CG6734 CG6734 K03130|1|2e-08|63.2|dgr:Dgri_GH20712|transcription initiation factor TFIID subunit D4 - - - 43230 1142.96 255.01 257.82 0.0158103606947086 Up 0.0920287940826839 BM-40-SPARC BM-40-SPARC, isoform B K08136|1|1e-10|67.8|oaa:100077472|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) GO:0031012//extracellular matrix GO:0046872//metal ion binding GO:0007417//central nervous system development;GO:0048598//embryonic morphogenesis;GO:0032940//secretion by cell;GO:0009888//tissue development;GO:0023060;GO:0048513//organ development 50178 460.00 3.895 1.13 -1.78530055564648 Down 0.554979527143046 CG15434 CG15434 K03946|1|2e-49|193|dme:Dmel_CG15434|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain - GO:0022904//respiratory electron transport chain 36504 1072.00 1.01 1.06 0.0697089718114045 Up 0.0561022322018227 CG13332 CG13332 - - - - 3771889 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 19835723 334.99 2.945 4.245 0.527496919722578 Up 0.348566900013208 - CG45011, isoform B - - - - 31137 746.94 35.905 31.455 -0.190895400358401 Down 0.364053625676925 CG14812 CG14812, isoform B - - - - 35112 2656.00 11.89 13.99 0.234647247419098 Up 0.335853916259411 CG10333 CG10333 K12858|1|0.0|1309|dme:Dmel_CG10333|ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13] GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377 35226 1153.62 15.135 14.01 -0.111431719396695 Down 0.203473781534804 CG10026 CG10026, isoform D K01104|1|8e-09|61.6|aag:AaeL_AAEL005492|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005501//retinoid binding;GO:0005501//retinoid binding;GO:0005501//retinoid binding GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 35307 1623.00 0.265 0.28 0.0794344674944049 Up 0.0463611147800819 Ugt37a1 UDP-glycosyltransferase 37a1 K00699|1|0.0|868|dme:Dmel_CG11012|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 34741 1188.94 22.28 54.115 1.2802793137976 Up 0.733126403381324 CG16826 CG16826, isoform B - - - - 46391 1176.00 147.84 83.085 -0.83137671753158 Down 0.707403249240523 CG11899 CG11899 K00831|1|0.0|723|dsi:Dsim_GD21426|phosphoserine aminotransferase [EC:2.6.1.52] GO:0044424//intracellular part GO:0008483//transaminase activity;GO:0048037//cofactor binding GO:0006563//L-serine metabolic process;GO:0008614//pyridoxine metabolic process 43623 1683.00 0.115 0.08 -0.523561956057013 Down 0.0682868841632545 PH4alphaSG2 prolyl-4-hydroxylase-alpha SG2 K00472|1|0.0|1075|dme:Dmel_CG1546|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0007431//salivary gland development;GO:0019538//protein metabolic process 40655 1597.18 34.045 35.83 0.0737251103591741 Up 0.178675208030643 CG12162 CG12162, isoform B K10290|1|3e-08|60.5|tgu:100227808|F-box protein 3 - - - 246682 3998.83 19.855 25.235 0.345923725773958 Up 0.491249504688945 CG17724 CG17724, isoform F - GO:0005622//intracellular - GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0030308//negative regulation of cell growth;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 3771891 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33878 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 38716 3034.00 5.015 5.33 0.0878858321469952 Up 0.113129045040285 CG10274 CG10274 K09228|1|8e-49|196|dre:555539|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 42735 3321.09 19.435 20.27 0.0606889811277016 Up 0.143243957205125 cenB1A centaurin beta 1A, isoform B K12489|1|0.0|1220|dsi:Dsim_GD21002|Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein - GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding GO:0006909//phagocytosis;GO:0032012//regulation of ARF protein signal transduction;GO:0006909//phagocytosis;GO:0032012//regulation of ARF protein signal transduction 49070 3684.52 60.1 52.59 -0.192576494117853 Down 0.385748249900938 Mbs myosin binding subunit, isoform Q K06270|1|0.0|773|dpo:Dpse_GA16721|protein phosphatase 1 regulatory subunit 12A GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004722//protein serine/threonine phosphatase activity GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009888//tissue development;GO:0048675//axon extension;GO:0042478//regulation of eye photoreceptor cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm 5740629 5891.00 8.06 9.765 0.276840205358824 Up 0.335622771100251 CG43795 CG43795 K08469|1|7e-75|283|bfo:BRAFLDRAFT_66969|G protein-coupled receptor 158 GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 37226 2732.00 0.01 0.02 1 Up 0.0497292299564126 CG10081 CG10081, isoform B - - - - 31533 2673.00 8.805 8.99 0.0299981116832391 Up 0.0753203011491217 CG4766 CG4766 - - - - 42545 4167.58 27.195 28.165 0.0505620457742339 Up 0.135550125478801 CG7956 CG7956, isoform G K01099|1|3e-51|204|bmy:Bm1_02165|phosphatidylinositol-bisphosphatase [EC:3.1.3.36] - - - 32619 15107.57 22.765 31.45 0.466242557747452 Up 0.571489895654471 para paralytic, isoform Z K05388|1|0.0|1972|dme:Dmel_CG9907|voltage-gated sodium channel alpha, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity;GO:0005272//sodium channel activity GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport;GO:0008049//male courtship behavior;GO:0017085//response to insecticide;GO:0030001//metal ion transport 4379888 1399.13 7.245 7.875 0.120294233717712 Up 0.170056795667679 BG642163 BG642163, isoform B - - - - 5740417 366.00 20.825 15.795 -0.398848558506037 Down 0.504490820235108 CG34242 CG34242, isoform B - - - - 7354423 927.02 25.525 33.985 0.412987161711633 Up 0.547913089420156 CG42307 CG42307, isoform D K10484|1|3e-11|71.6|dre:100001183|BTB/POZ domain-containing protein 12 GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0005488//binding;GO:0005488//binding GO:0007059//chromosome segregation;GO:0051276//chromosome organization;GO:0006310//DNA recombination;GO:0007059//chromosome segregation;GO:0051276//chromosome organization;GO:0006310//DNA recombination 43892 9956.75 95.355 134.42 0.495367314641545 Up 0.634592524105138 sif still life, isoform P K01168|1|0.0|3353|dme:Dmel_CG34418|pancreatic ribonuclease [EC:3.1.27.5];K05731|2|0.0|3063|dpo:Dpse_GA18858|T-cell lymphoma invasion and metastasis GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007266//Rho protein signal transduction 33707 884.00 10.375 10.385 0.00138987972299804 Up 0.0401862369568089 Jon25Bii jonah 25Bii, isoform B K01310|1|1e-125|448|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|4e-82|304|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41511 972.00 0.44 0.47 0.09515723304034 Up 0.0512812045964866 CG10035 CG10035, isoform B - - - - 45318 3502.78 4.065 5.025 0.305868243991263 Up 0.271133271694624 kn knot, isoform E K09103|1|0.0|1073|dya:Dyak_GE12286|early B-cell factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006952//defense response;GO:0051707//response to other organism;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0035171//lamellocyte differentiation;GO:0007380//specification of segmental identity, head;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching;GO:0006952//defense response;GO:0051707//response to other organism;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0035171//lamellocyte differentiation;GO:0007380//specification of segmental identity, head;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching;GO:0006952//defense response;GO:0051707//response to other organism;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0035171//lamellocyte differentiation;GO:0007380//specification of segmental identity, head;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching;GO:0006952//defense response;GO:0051707//response to other organism;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0035171//lamellocyte differentiation;GO:0007380//specification of segmental identity, head;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching 34722 1721.00 13.475 12.225 -0.140450807800272 Down 0.235735041606129 CG16812 CG16812 - - - - 19835885 544.00 0.47 0.49 0.0601209924375709 Up 0.0455355963545106 - CG44257 - - - - 37422 4513.43 15.28 17.13 0.164880608048251 Up 0.280246995112931 ASPP Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform C K12329|1|8e-18|93.6|mdo:100011797|protein phosphatase 1 regulatory subunit 12B - - - 42110 3384.00 1.85 2.52 0.445898462983604 Up 0.245905428609167 Hmx H6-like-homeobox, isoform E K09349|1|6e-58|226|dme:Dmel_CG34419|homeobox protein Nkx-5 - - - 2768949 391.00 5.59 6.05 0.114086859318767 Up 0.144267600052833 CG33276 CG33276 K12161|1|6e-54|208|dme:Dmel_CG33276|ubiquitin related modifier 1 GO:0044424//intracellular part - GO:0006399//tRNA metabolic process 31560 951.00 13.755 12.085 -0.186738666550628 Down 0.291275921278563 CG3781 CG3781 K11863|1|6e-06|51.6|ptr:738729|Ataxin-3 [EC:3.4.22.-] - - - 34018 1214.00 11.28 13.285 0.236031160091713 Up 0.335193501518954 CG5181 CG5181 - - GO:0005488//binding - 38845 3951.71 47 40.72 -0.206923195376667 Down 0.399385814291375 ltl larval translucida, isoform B K05401|1|5e-22|107|dme:Dmel_CG5195|toll-like recepto 3;K04308|3|1e-21|106|ecb:100064565|leucine-rich repeat-containing G protein-coupled receptor 5;K08399|5|1e-21|105|ecb:100052322|leucine-rich repeat-containing G protein-coupled receptor 6 - GO:0005488//binding - 318141 888.00 6.26 10.245 0.710685422078629 Up 0.539558842953375 CG32652 CG32652 - - - - 35286 2447.00 79.475 87.815 0.143966281441438 Up 0.323603222823933 sNPF short neuropeptide F precursor - - GO:0005179//hormone activity GO:0043410//positive regulation of MAPK cascade;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035264//multicellular organism growth;GO:0010259//multicellular organismal aging;GO:0030537//larval behavior;GO:0005991//trehalose metabolic process;GO:0008361//regulation of cell size;GO:0006006//glucose metabolic process;GO:0032094//response to food;GO:0007631//feeding behavior 42499 2799.00 9.445 8.035 -0.233252772713276 Down 0.292530709285431 sec15 Sec15 ortholog - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0033267//axon part;GO:0031982//vesicle - GO:0006903//vesicle targeting;GO:0007423//sensory organ development;GO:0009416//response to light stimulus;GO:0006935//chemotaxis;GO:0001505//regulation of neurotransmitter levels;GO:0016197//endosomal transport;GO:0006904//vesicle docking involved in exocytosis 34570 1697.00 0.045 0.03 -0.584962500721156 Down 0.047450799101836 sala spalt-adjacent, isoform C - - - GO:0032501//multicellular organismal process 33636 4186.75 34.415 34.955 0.0224613250263009 Up 0.0837075683529256 Atet ABC transporter expressed in trachea, isoform D K05680|1|0.0|646|cin:100179107|ATP-binding cassette, subfamily G (WHITE), member 4;K05679|2|7e-106|385|bfo:BRAFLDRAFT_82876|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559 - 34021 2185.34 219.58 205.51 -0.0955380590313609 Down 0.261227050587769 CG5261 CG5261, isoform F K00627|1|0.0|710|dme:Dmel_CG5261|pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016418;GO:0005488//binding;GO:0016418 GO:0006085//acetyl-CoA biosynthetic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006085//acetyl-CoA biosynthetic process;GO:0032787//monocarboxylic acid metabolic process 14462777 521.00 0.475 0.53 0.158064846232252 Up 0.0673292827895919 CG43924 CG43924 - - - - 42784 3545.05 50.165 57.925 0.207504988802915 Up 0.407740060758156 CG31145 CG31145, isoform F - - - - 44115 4271.09 22.39 18.215 -0.297727533109815 Down 0.443963809272223 Rgl Ral guanine nucleotide dissociation stimulator-like ortholog, isoform E K08732|1|6e-81|303|xtr:100135084|ral guanine nucleotide dissociation stimulator GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction 36927 1470.11 145.73 121.75 -0.259376129089452 Down 0.484777440232466 GstS1 glutathione S transferase S1, isoform D K00799|1|3e-115|415|dme:Dmel_CG8938|glutathione S-transferase [EC:2.5.1.18];K01830|3|3e-77|289|aag:AaeL_AAEL011741|prostaglandin-H2 D-isomerase [EC:5.3.99.2] - - - 39621 858.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 Ocho ocho, isoform C - - - GO:0048513//organ development 41341 1036.00 486.835 452.71 -0.104845716458327 Down 0.265189539030511 Tctp translationally controlled tumor protein ortholog - GO:0043234//protein complex;GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0030695//GTPase regulator activity GO:0035264//multicellular organism growth;GO:0008361//regulation of cell size 5740457 3605.58 21.51 24.13 0.165820390792691 Up 0.315017831197992 CG17162 CG17162, isoform H - - - - 41072 5397.00 5.96 6.455 0.115104764845029 Up 0.153876634526483 CG11970 CG11970, isoform B K11671|1|0.0|2575|dme:Dmel_CG11970|nuclear factor related to kappa-B-binding protein GO:0043231//intracellular membrane-bounded organelle - - 42119 464.00 0.73 0.22 -1.73039294024272 Down 0.27212389380531 CG14324 CG14324 - - - - 39304 1156.46 324.9 210.44 -0.626586788482056 Down 0.680854576674151 CG6084 CG6084, isoform D K00011|1|0.0|650|dsi:Dsim_GD12789|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 31331 3605.16 17.39 20.56 0.241582331887291 Up 0.380233786818122 Mnt Mnt, isoform K K09115|1|8e-15|82.8|api:100166423|MAX-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding GO:0016049//cell growth;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0016049//cell growth;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0016049//cell growth;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0016049//cell growth;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression 318562 3002.00 2.52 4.07 0.691605060766331 Up 0.391559899616959 CG31029 CG31029 - - - - 34636 1841.30 31.985 29.22 -0.13043930512205 Down 0.277968564258354 Rab6 Rab6, isoform B K07976|1|4e-115|415|dpo:Dpse_GA19714|Rab family, other;K07893|5|6e-99|361|tgu:100190586|Ras-related protein Rab-6A - GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding GO:0016192//vesicle-mediated transport;GO:0035556//intracellular signal transduction;GO:0019094//pole plasm mRNA localization;GO:0048592//eye morphogenesis;GO:0007017//microtubule-based process 38786 5005.31 18.935 23.17 0.291202622980402 Up 0.437755910711927 corn cornetto, isoform E K13163|1|7e-08|60.8|dgr:Dgri_GH10167|male-specific lethal 1;K13172|2|5e-06|54.7|mdo:100018249|serine/arginine repetitive matrix protein 2;K11499|3|9e-06|53.9|oaa:100079351|centromere protein F GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0015631//tubulin binding - 43387 8682.00 14.185 16.28 0.198734548991888 Up 0.319145423325849 CG10011 CG10011 K10380|1|2e-68|262|ecb:100062775|ankyrin - - - 246449 1681.00 0.05 0.195 1.96347412397489 Up 0.139050323603223 CG30091 CG30091 K01321|1|2e-25|117|cfa:404015|coagulation factor IX (Christmas factor) [EC:3.4.21.22];K09637|3|6e-25|115|tgu:100220511|transmembrane protease, serine 6 [EC:3.4.21.-];K01320|4|2e-24|113|dre:114423|coagulation factor VII [EC:3.4.21.21];K09628|5|3e-24|113|xtr:595077|protease, serine 27 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835209 1064.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 39090 1125.00 28.925 26.665 -0.117369631311858 Down 0.254061550653811 Bet3 BET3 ortholog - GO:0044424//intracellular part GO:0009975//cyclase activity;GO:0005506//iron ion binding GO:0050658//RNA transport;GO:0006164//purine nucleotide biosynthetic process 12798142 1075.68 0.475 0.84 0.822461814447812 Up 0.198124422137102 34002 2067.21 56.07 38.92 -0.526717359685203 Down 0.622440892880729 CG4502 CG4502, isoform B K10582|1|8e-132|471|dme:Dmel_CG4502|ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process 46155 4001.00 14.43 10.24 -0.494855584491198 Down 0.510599656584335 CG31195 CG31195 K08469|1|2e-16|88.6|bfo:BRAFLDRAFT_66969|G protein-coupled receptor 158 - - - 32595 1227.00 336.85 294.055 -0.196020277575981 Down 0.427024171179501 Cyp1 cyclophilin 1 K09565|1|3e-127|454|dme:Dmel_CG9916|peptidyl-prolyl isomerase F (cyclophilin F) [EC:5.2.1.8] GO:0015630//microtubule cytoskeleton;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0008023//transcription elongation factor complex GO:0016859//cis-trans isomerase activity;GO:0019887//protein kinase regulator activity GO:0044267//cellular protein metabolic process;GO:0048102//autophagic cell death 19835646 1210.00 0.925 1.795 0.956458573306739 Up 0.32020208691058 39525 2637.00 1.93 1.415 -0.447798794436198 Down 0.214040417382116 CG10710 CG10710 - - - - 38113 942.59 43.69 47.8 0.129707512423893 Up 0.291639149385814 CG9205 CG9205, isoform B K08283|1|3e-09|62.4|gga:427209|Goodpasture-antigen-binding protein kinase [EC:2.7.11.9] - - GO:0006629//lipid metabolic process;GO:0006629//lipid metabolic process 36432 6472.86 10.34 12.145 0.23212630432093 Up 0.3195086514331 Su(z)2 suppressor of zeste 2, isoform C K11459|1|1e-35|153|aga:AgaP_AGAP006403|polycomb group RING finger protein 4 GO:0005720//nuclear heterochromatin;GO:0005720//nuclear heterochromatin GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 38879 3518.05 5.435 5.515 0.0210808505640735 Up 0.0559701492537313 pbl pebble, isoform F K10728|1|2e-16|89.0|nve:NEMVE_v1g112203|topoisomerase (DNA) II binding protein 1;K05730|2|2e-16|89.0|bmy:Bm1_13845|vav oncogene;K05723|4|2e-16|89.0|tgu:100222451|FYVE, RhoGEF and PH domain containing 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0051234//establishment of localization;GO:0007266//Rho protein signal transduction;GO:0007051//spindle organization;GO:0065008;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0007399//nervous system development;GO:0007509//mesoderm migration involved in gastrulation;GO:0051234//establishment of localization;GO:0007266//Rho protein signal transduction;GO:0007051//spindle organization;GO:0065008;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0007399//nervous system development;GO:0007509//mesoderm migration involved in gastrulation;GO:0051234//establishment of localization;GO:0007266//Rho protein signal transduction;GO:0007051//spindle organization;GO:0065008;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0007399//nervous system development;GO:0007509//mesoderm migration involved in gastrulation;GO:0051234//establishment of localization;GO:0007266//Rho protein signal transduction;GO:0007051//spindle organization;GO:0065008;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0007399//nervous system development;GO:0007509//mesoderm migration involved in gastrulation;GO:0051234//establishment of localization;GO:0007266//Rho protein signal transduction;GO:0007051//spindle organization;GO:0065008;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0007399//nervous system development;GO:0007509//mesoderm migration involved in gastrulation 43240 1882.90 144.185 176.52 0.291910567953444 Up 0.518194426099591 CG6330 CG6330, isoform B K00757|1|0.0|699|der:Dere_GG12162|uridine phosphorylase [EC:2.4.2.3] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 31046 839.00 200.775 77.01 -1.38246193795272 Down 0.760038304054947 CG3699 CG3699 K00079|1|1e-26|120|cel:R11D1.11|carbonyl reductase (NADPH) [EC:1.1.1.184];K11147|2|2e-26|119|api:100164938|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-];K00120|4|3e-25|115|dme:Dmel_CG7322| [EC:1.1.-.-];K03793|5|6e-25|114|bfo:BRAFLDRAFT_130700|pteridine reductase [EC:1.5.1.33] - - - 34042 1350.00 0.17 0.605 1.83140039602426 Up 0.249504688944657 CG7025 CG7025 K01290|1|0.0|842|dme:Dmel_CG7025|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 19835731 628.00 0.07 0.36 2.36257007938471 Up 0.210705322942808 33759 3775.72 16.305 8.7 -0.906227135012375 Down 0.631653678510104 vri vrille, isoform F K12114|1|0.0|1022|dme:Dmel_CG14029|vrille - GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-dependent;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-dependent;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-dependent 41647 2939.00 5.045 4.95 -0.0274257441393852 Down 0.0602958658037247 CG9799 CG9799 K10599|1|5e-09|63.9|nve:NEMVE_v1g199033|pre-mRNA-processing factor 19 [EC:6.3.2.19];K13111|2|6e-09|63.5|dvi:Dvir_GJ22777|WD40 repeat-containing protein SMU1 - - - 38144 2373.00 9.08 9.05 -0.00477450532034723 Down 0.0427618544445912 Rabex-5 Rabaptin-5-associated exchange factor for Rab5 ortholog - - GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 3771818 1023.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 His1:CG33804 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 41876 1589.00 51.77 57.165 0.143015790672397 Up 0.312937524765553 CG5073 cerebral cavernous malformation 3 ortholog - - - - 35628 1077.00 1.385 1.28 -0.113742166049188 Down 0.0734050984017963 Tsp42Eq tetraspanin 42Eq K06497|1|4e-14|79.0|dan:Dana_GF13154|CD63 antigen GO:0031224//intrinsic to membrane - - 41350 2322.00 19.565 23 0.233358750930944 Up 0.380134724607053 CG10703 GCC88 ortholog K02084|1|4e-77|289|spu:591503|apoptotic protease-activating factor;K12478|2|1e-18|95.5|ssc:100153403|early endosome antigen 1 - - - 32538 2646.00 1.14 2.005 0.814568412290179 Up 0.309305243693039 CG8565 CG8565 K08831|1|4e-99|362|nvi:100120098|SFRS protein kinase [EC:2.7.11.1];K08832|4|2e-91|337|dre:566605|serine/threonine kinase 23 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0022414//reproductive process;GO:0007275//multicellular organismal development 39904 3675.00 4.255 4.445 0.063024287143807 Up 0.0850614185708625 CG7728 CG7728 - GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0022613//ribonucleoprotein complex biogenesis 40195 3890.18 8.075 9.535 0.239770678731469 Up 0.299564126271298 sNPF-R short neuropeptide F receptor, isoform B K04209|1|0.0|1014|dme:Dmel_CG7395|neuropeptide Y receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 43290 1545.58 56.825 49.295 -0.205084457815678 Down 0.406848500858539 CG5938 CG5938, isoform F - - - - 10178911 368.00 0.235 0.395 0.749191896499465 Up 0.126898692378814 CG42870 CG42870 - - - - 41975 2011.00 13.425 7.255 -0.887874568806031 Down 0.611411966715097 Zip3 Zinc/iron regulated transporter-related protein 89B - - - - 42805 1627.00 90.415 51.865 -0.801800843370937 Down 0.69577994980848 Tbp-1 regulatory particle triple-A ATPase 5 K03065|1|0.0|835|dya:Dyak_GE10392|26S proteasome regulatory subunit T5 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process 33751 1116.00 4.95 4.23 -0.226770861847022 Down 0.217045304451195 CG14034 CG14034, isoform C K01046|1|1e-33|144|tca:657679|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:0019637//organophosphate metabolic process 7354379 710.90 8.075 8.25 0.0309318595518909 Up 0.073702285035002 CG42372 CG42372, isoform C K02835|1|9e-09|60.5|aga:AgaP_AGAP012082|peptide chain release factor RF-1 - GO:0008079//translation termination factor activity;GO:0008079//translation termination factor activity GO:0006412//translation;GO:0006412//translation 36911 1763.58 48.685 52.31 0.103609428078153 Up 0.242504292695813 CG6805 CG6805, isoform B K01106|1|5e-83|308|dme:Dmel_CG9784|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] - - - 42307 1278.00 0.48 0.235 -1.03037364904352 Down 0.166391493858143 CG11703 CG11703 K01540|1|3e-21|102|dwi:Dwil_GK24210|sodium/potassium-transporting ATPase subunit beta GO:0016020//membrane GO:0008556//potassium-transporting ATPase activity GO:0009206;GO:0030001//metal ion transport 32933 3508.00 4.59 4.425 -0.0528166984434478 Down 0.0768722757891956 CG32533 CG32533, isoform B K12813|1|3e-90|333|cbr:CBG20862|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377 47249 5738.74 13.87 13.425 -0.0470456994508276 Down 0.111742174085326 woc without children, isoform E - GO:0032991//macromolecular complex;GO:0000781//chromosome, telomeric region;GO:0005700//polytene chromosome;GO:0000785//chromatin;GO:0032991//macromolecular complex;GO:0000781//chromosome, telomeric region;GO:0005700//polytene chromosome;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0000723//telomere maintenance;GO:0006351//transcription, DNA-dependent;GO:0000723//telomere maintenance;GO:0006351//transcription, DNA-dependent 36726 1824.21 51.725 48.67 -0.0878289654688696 Down 0.22219653942676 Flo-1 flotillin 1, isoform B K07192|1|0.0|657|dme:Dmel_CG8200|flotillin GO:0005901//caveola;GO:0005901//caveola - - 37932 2218.00 12.525 14.54 0.215216665837023 Up 0.326013736626601 CG3548 CG3548 - - - - 31692 2135.00 0.18 0.165 -0.125530882083859 Down 0.0444459120327566 Ir7c ionotropic receptor 7c, isoform B K05207|1|1e-08|62.0|bfo:BRAFLDRAFT_75112|glutamate receptor, ionotropic, delta 2;K09884|2|3e-07|57.4|tca:663053|aquaporin rerated protein, invertebrate;K05206|3|1e-06|55.5|mdo:100013587|glutamate receptor, ionotropic, delta 1 - - - 35215 1761.76 85.545 90.48 0.0809153958989558 Up 0.212917712323339 Pax paxillin, isoform K K05760|1|4e-161|567|dsi:Dsim_GD21763|paxillin GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction;GO:0005924//cell-substrate adherens junction GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007010//cytoskeleton organization;GO:0007444//imaginal disc development;GO:0032318//regulation of Ras GTPase activity;GO:0007010//cytoskeleton organization;GO:0007444//imaginal disc development;GO:0032318//regulation of Ras GTPase activity;GO:0007010//cytoskeleton organization;GO:0007444//imaginal disc development;GO:0032318//regulation of Ras GTPase activity;GO:0007010//cytoskeleton organization;GO:0007444//imaginal disc development;GO:0032318//regulation of Ras GTPase activity;GO:0007010//cytoskeleton organization;GO:0007444//imaginal disc development;GO:0032318//regulation of Ras GTPase activity;GO:0007010//cytoskeleton organization;GO:0007444//imaginal disc development;GO:0032318//regulation of Ras GTPase activity 39025 1011.01 39.075 47.72 0.288348169808201 Up 0.483390569277506 CG5021 CG5021, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 41784 1652.48 56.36 50.945 -0.145731051697605 Down 0.326211861048739 CG7530 CG7530, isoform D K07297|1|5e-37|155|dya:Dyak_GE24027|adiponectin receptor - - - 42843 4410.56 38.07 41.065 0.109254728175584 Up 0.252905824858011 KrT95D krueppel target at 95D, isoform F - - - - 32021 4184.00 8.4 6.81 -0.302734529654051 Down 0.334367983093383 CG1582 CG1582, isoform B K13184|1|3e-122|440|dse:Dsec_GM16493|ATP-dependent RNA helicase A [EC:3.6.4.13] - GO:0046914//transition metal ion binding;GO:0032559;GO:0042623//ATPase activity, coupled - 19834869 331.00 1.055 0.155 -2.76690287832031 Down 0.382446176198653 12798500 599.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG43311 CG43311 - - - - 41312 2357.00 11.045 11.635 0.075077792050074 Up 0.143508123101308 CG4596 CG4596 - - - - 3771991 1023.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 His1:CG33855 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 37389 682.00 16.125 17.67 0.132002879353638 Up 0.243098665962224 mRpL54 mitochondrial ribosomal protein L54 - - - - 326137 774.00 1.475 1.25 -0.238786859587116 Down 0.118313300752873 CG31419 CG31419 - - - - 37553 569.00 1.435 1.365 -0.0721497857558354 Down 0.0606590939109761 CG11298 CG11298 - - - - 12798403 795.00 0.105 0.06 -0.807354922057604 Down 0.07657508915599 CG43188 CG43188 - - - - 42892 1548.00 0.77 1.555 1.0139842294357 Up 0.309899616959451 CG13611 CG13611 K00274|1|9e-178|623|dan:Dana_GF16121|monoamine oxidase [EC:1.4.3.4] - - GO:0016109 43270 2897.00 0.48 0.69 0.523561956057013 Up 0.136738872011623 CG6059 CG6059 K12478|1|9e-24|112|mcc:710381|early endosome antigen 1 - - - 36459 721.80 17.615 18.67 0.0839174527312382 Up 0.172698454629507 CG4646 CG4646, isoform B - - - - 45707 1681.00 1.07 2.875 1.42595115943059 Up 0.468101968035927 CG18031 CG18031 K13356|1|1e-56|221|api:100166286|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 36134 918.00 8.945 9.64 0.107951664178054 Up 0.17250033020737 CG12935 CG12935, isoform B - - - - 40033 1451.47 33.11 33.03 -0.00349004111147416 Down 0.0449742438251222 GNBP2 Gram-negative bacteria binding protein 2, isoform D - - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0051635//bacterial cell surface binding;GO:0004872//receptor activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0051635//bacterial cell surface binding;GO:0004872//receptor activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0051635//bacterial cell surface binding;GO:0004872//receptor activity GO:0044238//primary metabolic process;GO:0006950//response to stress;GO:0044238//primary metabolic process;GO:0006950//response to stress;GO:0044238//primary metabolic process;GO:0006950//response to stress 36229 2286.00 1.49 1.61 0.111748357652455 Up 0.0789195614846123 CG13203 CG13203, isoform D - - - - 40048 1993.00 325.095 270.38 -0.265872927916033 Down 0.503401135913354 Cat catalase K03781|1|0.0|1056|dme:Dmel_CG6871|catalase [EC:1.11.1.6] GO:0016020//membrane;GO:0042579//microbody GO:0005506//iron ion binding;GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0010259//multicellular organismal aging;GO:0016337//cell-cell adhesion;GO:0000302//response to reactive oxygen species 40648 1362.00 1.33 0.68 -0.96781959425085 Down 0.278364813102628 Or83a odorant receptor 83a K08471|1|0.0|886|dme:Dmel_CG10612|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 43555 1507.00 1.735 2.19 0.335995207022913 Up 0.192940166424515 sas-6 spindle assembly abnormal 6 ortholog K12478|1|3e-10|66.6|gga:417896|early endosome antigen 1;K14000|5|4e-10|66.2|dre:553448|ribosome-binding protein 1 - - - 41044 3460.49 17.03 17.09 0.00507396199759665 Up 0.0502575617487782 CG9801 CG9801, isoform C - - - - 37411 4443.83 18.235 19.755 0.115507646641559 Up 0.231475366530181 CG4266 CG4266, isoform D K13191|1|6e-168|592|dme:Dmel_CG4266|RNA-binding protein 16 - - - 2768912 825.00 0.055 0.195 1.82597060022495 Up 0.13380002641659 CG33299 CG33299, isoform C - - - - 37866 2537.48 9.74 10.28 0.0778465871115359 Up 0.139182406551314 CG4065 CG4065, isoform B - - - - 38886 2173.00 38.305 39.56 0.0465097048503959 Up 0.141989169198256 CG8042 CG8042 - - - - 32835 694.00 1.49 0.33 -2.17477440110371 Down 0.413353586052041 CG15043 CG15043, isoform B - - - - 34925 727.26 164.265 179.065 0.12445825856445 Up 0.297814027209087 l(2)35Di lethal (2) 35Di, isoform C K03962|1|4e-66|250|dme:Dmel_CG13240|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 6 [EC:1.6.5.3 1.6.99.3] - GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 43677 1784.00 8.51 1.975 -2.1073064786215 Down 0.680227182670717 CG15553 CG15553 - - - GO:0006810//transport 37624 1543.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG9825 CG9825 K08193|1|4e-71|268|tca:659046|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport 42105 1848.94 29.975 35.49 0.243652820759359 Up 0.419033152819971 CG5823 CG5823, isoform B K04554|1|4e-139|495|dme:Dmel_CG5823|ubiquitin-conjugating enzyme E2 J2 [EC:6.3.2.19] - - - 43345 1341.00 23.945 28.035 0.227504634230313 Up 0.392550521727645 mRpS22 mitochondrial ribosomal protein S22 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity - 19834745 1556.00 0.355 0.275 -0.368387405980022 Down 0.0865473517368908 37526 960.00 4.02 0.705 -2.51150033878013 Down 0.607185312376172 CG34205 CG34205 - - - - 39438 2260.69 15.63 15.54 -0.00833127459195425 Down 0.053625676925109 sowah sosondowah, isoform J K10329|1|3e-10|67.4|xtr:549908|ankyrin repeat and SOCS box protein 7 - - - 19835849 877.00 0.195 0.595 1.6094155444457 Up 0.237749306564523 34336 1149.00 105.005 39.935 -1.39473240722276 Down 0.753203011491216 obst-B obstructor-B K01873|1|1e-13|77.4|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K05030|5|4e-13|75.9|cin:100175971|calcium-activated chloride channel family member 4 - GO:0030247//polysaccharide binding GO:0006022 19835544 1501.00 0.15 0.42 1.48542682717024 Up 0.187590807026813 41019 2060.00 2.255 1.265 -0.833990048561071 Down 0.330933826443006 Cyp313b1 Cyp313b1, isoform B K00517|1|0.0|1020|dme:Dmel_CG9716| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 43093 1670.78 30.035 33.45 0.155361547002353 Up 0.319706775855237 jigr1 jing interacting gene regulatory 1, isoform G K09427|1|1e-08|61.2|dpo:Dpse_GA13983|Adh transcription factor 1 - - - 2768995 5001.39 2.355 1.15 -1.03409319866841 Down 0.380266807555145 CG43980 CG43980, isoform C K10521|1|0.0|2184|dme:Dmel_CG33291|ankyrin repeat and BTB/POZ domain-containing protein 2 GO:0043229//intracellular organelle GO:0003676//nucleic acid binding - 43501 7624.17 22.455 27.925 0.314520558591105 Up 0.470908730682869 Kul Kuzbanian-like, isoform C K06704|1|0.0|2533|dme:Dmel_CG1964|disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37340 785.29 12.34 17.565 0.509361182072953 Up 0.539327697794215 CG16799 CG16799, isoform B K01185|1|1e-105|382|dme:Dmel_CG16799|lysozyme [EC:3.2.1.17];K13915|5|1e-21|102|cqu:CpipJ_CPIJ005450|lysozyme C [EC:3.2.1.17] - - - 34549 4515.86 3.615 3.63 0.00597390104463287 Up 0.041044776119403 Nup160 nucleoporin 160kD, isoform B K10756|1|5e-59|230|dme:Dmel_CG6258|replication factor C subunit 3/5 - - - 33946 3017.00 1.28 2.285 0.83605035505807 Up 0.332882049927354 TTLL3B tubulin tyrosine ligase-like 3B K05755|1|2e-58|227|tgu:100190205|actin related protein 2/3 complex, subunit 4;K06047|4|1e-21|105|bta:514559|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0003006//developmental process involved in reproduction 37900 1340.00 1.14 1.675 0.555127271180393 Up 0.226026944921411 CG3483 CG3483 K00030|1|0.0|725|dme:Dmel_CG3483|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] - GO:0004448//isocitrate dehydrogenase activity;GO:0046872//metal ion binding;GO:0000166//nucleotide binding GO:0008152//metabolic process 31406 1740.80 300.94 286.44 -0.0712429056583637 Down 0.202450138687095 l(1)G0334 lethal (1) G0334, isoform D K00161|1|0.0|818|dse:Dsec_GM12361|pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] GO:0043234//protein complex;GO:0043227//membrane-bounded organelle;GO:0043234//protein complex;GO:0043227//membrane-bounded organelle;GO:0043234//protein complex;GO:0043227//membrane-bounded organelle;GO:0043234//protein complex;GO:0043227//membrane-bounded organelle GO:0004738//pyruvate dehydrogenase activity;GO:0004738//pyruvate dehydrogenase activity;GO:0004738//pyruvate dehydrogenase activity;GO:0004738//pyruvate dehydrogenase activity GO:0032787//monocarboxylic acid metabolic process;GO:0006007//glucose catabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006007//glucose catabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006007//glucose catabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006007//glucose catabolic process 36260 2823.00 3.2 3.535 0.143638309922037 Up 0.133899088627658 Sobp sine oculis-binding protein, isoform B - - - - 34705 1303.00 0.035 0.07 1 Up 0.0725795799762251 Pk34A Pk34A K08822|1|2e-58|226|mcc:707037|glycogen synthase kinase 3 alpha [EC:2.7.11.26] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 42747 6713.99 52.275 57.28 0.131910335787315 Up 0.297318716153745 CG4467 CG4467, isoform B K05324|1|9e-99|363|tca:660459|potassium voltage-gated channel KQT-like subfamily, invertebrate;K11141|3|2e-92|342|ame:412263|glutamyl aminopeptidase [EC:3.4.11.7];K11140|5|2e-72|275|cin:100187078|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 34184 2522.00 3.815 4.4 0.205820466690129 Up 0.19208162726192 CG13097 CG13097 K06670|1|0.0|694|dpo:Dpse_GA12044|cohesin complex subunit SCC1 GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex - GO:0010467//gene expression;GO:0009987//cellular process 44205 19033.53 24.21 25.22 0.0589651963292833 Up 0.150178311979923 spen split ends, isoform H K13190|1|2e-31|141|nve:NEMVE_v1g237983|RNA-binding protein 15 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0016477//cell migration;GO:0003002//regionalization;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0016477//cell migration;GO:0003002//regionalization;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0016477//cell migration;GO:0003002//regionalization;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development 246553 2217.00 17.755 16.34 -0.119817376875288 Down 0.226819442609959 CG30345 CG30345 - GO:0044464//cell part - GO:0006810//transport 117496 1581.29 1.855 1.47 -0.335603031784439 Down 0.174910844010038 Gr28b gustatory receptor 28b, isoform E K08471|1|0.0|796|dpo:Dpse_GA12528|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity GO:0023052//signaling;GO:0007606//sensory perception of chemical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007606//sensory perception of chemical stimulus 31317 4493.92 21.275 24.645 0.212135849097906 Up 0.364449874521199 CG10804 CG10804, isoform D K05336|1|1e-164|581|aag:AaeL_AAEL003860|solute carrier family 6 (neurotransmitter transporter), invertebrate - - - 41275 1165.00 70.665 74.51 0.0764382301933639 Up 0.209615638621054 CG14688 CG14688 K00477|1|9e-06|50.8|nve:NEMVE_v1g236889|phytanoyl-CoA hydroxylase [EC:1.14.11.18] - - - 42800 1864.00 0.295 0.435 0.560300446486887 Up 0.112897899881125 CG10232 CG10232 K01362|1|6e-42|171|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|1e-35|150|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32610 4769.10 1.995 2.09 0.067114195858537 Up 0.0656122044644036 CG4301 CG4301, isoform C K01530|1|0.0|1261|aag:AaeL_AAEL012549|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559 GO:0009206;GO:0006869//lipid transport 41687 2122.00 251.95 65.875 -1.93533449444518 Down 0.787148329150707 Cht5 Cht5 K01183|1|0.0|1044|dme:Dmel_CG9307|chitinase [EC:3.2.1.14] - - - 37112 765.00 33.125 14.755 -1.16671653379328 Down 0.706709813763043 GstE7 glutathione S transferase E7 K00799|1|4e-125|446|dme:Dmel_CG17531|glutathione S-transferase [EC:2.5.1.18] - - - 39452 1253.02 2.395 4.45 0.89377968011758 Up 0.459285431250825 CG17666 CG17666, isoform B - - - - 3346204 615.00 0.265 0.225 -0.236067358233525 Down 0.0623761722361643 CheB53b chemosensory protein B 53b - GO:0044421//extracellular region part - GO:0009593//detection of chemical stimulus 35279 738.67 920.985 1029.51 0.16070827887677 Up 0.374124950468894 CoIV cytochrome c oxidase subunit IV, isoform D K02263|1|5e-102|370|dme:Dmel_CG10664|cytochrome c oxidase subunit IV [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 43710 2777.90 5.915 6.06 0.0349396251331625 Up 0.06927750627394 CG11337 CG11337, isoform E K00962|1|0.0|1452|dsi:Dsim_GD16436|polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0016779//nucleotidyltransferase activity;GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0016779//nucleotidyltransferase activity;GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0016779//nucleotidyltransferase activity;GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0016779//nucleotidyltransferase activity GO:0006401//RNA catabolic process;GO:0010467//gene expression;GO:0006401//RNA catabolic process;GO:0010467//gene expression;GO:0006401//RNA catabolic process;GO:0010467//gene expression;GO:0006401//RNA catabolic process;GO:0010467//gene expression 19835985 382.00 0.805 0.13 -2.63047715997352 Down 0.33502839783384 5740541 376.00 62.49 123.345 0.981001989506285 Up 0.722130497952714 CG34180 CG34180 - - - - 19835676 1054.00 1.815 2 0.140030451778974 Up 0.101571787082288 38694 3716.83 11.235 14.14 0.331781995629492 Up 0.42226918504821 CG6619 short spindle 6, isoform B K08789|1|4e-07|57.8|dre:100001267|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - GO:0005488//binding - 37895 3285.27 13.42 12.755 -0.0733217725977113 Down 0.142649583938714 SerT serotonin transporter, isoform B K05037|1|0.0|1311|dya:Dyak_GE11465|solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 GO:0016021//integral to membrane;GO:0033267//axon part GO:0005326//neurotransmitter transporter activity;GO:0008504//monoamine transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005216//ion channel activity GO:0001504//neurotransmitter uptake;GO:0006909//phagocytosis;GO:0015844//monoamine transport 10178816 3436.00 1.37 1.955 0.512992714346825 Up 0.233522652225598 pre-mod(mdg4)-U pre-mod(mdg4)-U - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 39886 1047.00 0.33 0.86 1.38187063534364 Up 0.267996301677453 CG13029 CG13029, isoform D - - GO:0046914//transition metal ion binding - 33541 3062.00 10.915 6.61 -0.723589953483099 Down 0.551248183859464 CG9663 CG9663 K05680|1|6e-116|419|cin:100179107|ATP-binding cassette, subfamily G (WHITE), member 4;K05679|2|3e-115|416|bfo:BRAFLDRAFT_82876|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 35442 5625.43 47.2 51.65 0.129981489503218 Up 0.293851538766345 CG42748 CG42748, isoform M - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 41530 1623.00 0.555 0.755 0.443988872974973 Up 0.130167745344076 CG5245 CG5245 K09228|1|1e-116|420|mmu:630579|KRAB domain-containing zinc finger protein - - - 38622 2930.00 1.715 2.41 0.490824570057149 Up 0.255580504556862 Lkr leucokinin receptor K04225|1|0.0|1014|dme:Dmel_CG10626|tachykinin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 35050 1251.00 0.47 0.5 0.0892673380970873 Up 0.0504226654338925 CG18563 CG18563 K09615|1|2e-23|110|ecb:100067538|tryptase gamma 1 [EC:3.4.21.-];K08664|2|1e-21|104|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33125 4269.72 11.03 10.68 -0.0465211439038289 Down 0.103123761722362 CG42343 CG42343, isoform G K06774|1|9e-27|122|gga:395450|neurotrimin - - - 37137 783.00 18.87 19.87 0.0744974496492249 Up 0.15998547087571 CG5323 CG5323 - - - - 41941 2693.00 0.39 0.42 0.106915203916512 Up 0.052073702285035 Rbf2 Retinoblastoma-family protein 2 K04681|1|3e-66|253|dvi:Dvir_GJ19490|retinoblastoma-like - - - 19835171 416.00 0.115 0.12 0.0614005446641436 Up 0.0422335226522256 35167 626.87 0.64 1.58 1.3037807481771 Up 0.349722625809008 CG15172 CG15172, isoform D - - - - 46032 758.00 12.235 11.25 -0.12108909997499 Down 0.201492537313433 Bka bekka K07158|1|7e-107|386|dme:Dmel_CG4539| - GO:0030528//transcription regulator activity GO:0006338//chromatin remodeling 7354409 2259.00 10.43 10.87 0.0596127825075438 Up 0.118082155593713 CG42381 CG42381 K05284|1|0.0|845|dme:Dmel_CG9865|phosphatidylinositol glycan, class M [EC:2.4.1.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016757//transferase activity, transferring glycosyl groups GO:0006497//protein lipidation 38988 1324.34 340.625 257.83 -0.401764185463936 Down 0.601241579712059 Zasp66 Z band alternatively spliced PDZ-motif protein 66, isoform O - GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 12798083 159.00 0.705 0.01 -6.13955135239879 Down 0.42887333245278 39137 2175.06 213.105 235.53 0.144346388028727 Up 0.336448289525822 vsg visgun, isoform E K06546|1|8e-18|92.4|dme:Dmel_CG16707|CD164 antigen GO:0031982//vesicle;GO:0031982//vesicle;GO:0031982//vesicle;GO:0031982//vesicle - GO:0008306//associative learning;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0008283//cell proliferation 37245 4322.00 0.67 1.035 0.627397767041552 Up 0.187491744815744 Oseg6 outer segment 6 - - - - 14462571 618.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 33040 631.84 652.52 663.755 0.0246287020926334 Up 0.0938779553559635 Obp19d Odorant-binding protein 19d, isoform B - - GO:0008144//drug binding;GO:0005549//odorant binding;GO:0008144//drug binding;GO:0005549//odorant binding GO:0051234//establishment of localization;GO:0051234//establishment of localization 19835631 598.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 31673 1477.00 0.49 0.745 0.604458676346953 Up 0.154834235900145 CG15035 CG15035 - - - - 40085 1233.00 16.075 10.635 -0.595998704254637 Down 0.56151763307357 CG10424 CG10424 - - - - 32272 1195.13 10.55 10.92 0.049729857325305 Up 0.105270109628847 CG2453 CG2453, isoform C K06127|1|7e-167|586|dme:Dmel_CG2453|ubiquinone biosynthesis methyltransferase [EC:2.1.1.-] - GO:0016741 - 38981 7803.55 59.335 74.405 0.326516213457119 Up 0.535233126403381 CG43078 CG43078, isoform N - - - - 32536 4062.64 28.045 29.335 0.06487940898958 Up 0.157640998547088 sd scalloped, isoform T K09448|1|0.0|879|dse:Dsec_GM22588|TEA domain family member 1/3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0055001//muscle cell development 38437 1201.00 1.02 1.67 0.711278950502557 Up 0.261854444591203 CG10862 CG10862 K06689|1|0.0|643|dme:Dmel_CG10862|ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0000166//nucleotide binding;GO:0019787//small conjugating protein ligase activity GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 39097 1432.57 5.045 7.585 0.588294911140676 Up 0.460672302205785 CG3552 CG3552, isoform D - - - - 14462394 1520.00 8.65 8.7 0.00831526821200343 Up 0.0492999603751156 32172 1885.00 2.845 1.62 -0.812434839421957 Down 0.365374455157839 Cyp318a1 Cyp318a1 K00517|1|0.0|1050|dme:Dmel_CG1786| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 40138 3720.74 25.06 26.115 0.0594922890503966 Up 0.151565182934883 Lon Lon protease, isoform C K08675|1|0.0|1855|dme:Dmel_CG8798|Lon-like ATP-dependent protease [EC:3.4.21.-] GO:0005759//mitochondrial matrix;GO:0005759//mitochondrial matrix GO:0003723//RNA binding;GO:0004175//endopeptidase activity;GO:0010843;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0004175//endopeptidase activity;GO:0010843;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0043566//structure-specific DNA binding GO:0006979//response to oxidative stress;GO:0006996//organelle organization;GO:0051259//protein oligomerization;GO:0019941//modification-dependent protein catabolic process;GO:0051131//chaperone-mediated protein complex assembly;GO:0006979//response to oxidative stress;GO:0006996//organelle organization;GO:0051259//protein oligomerization;GO:0019941//modification-dependent protein catabolic process;GO:0051131//chaperone-mediated protein complex assembly 31782 1570.00 123.05 131.775 0.0988320342713724 Up 0.256637168141593 CG12116 CG12116 K00072|1|2e-144|512|dme:Dmel_CG12116|sepiapterin reductase [EC:1.1.1.153] - GO:0003824//catalytic activity - 34866 643.00 4.23 4.555 0.106793390682101 Up 0.121186104873861 Mst35Ba Male-specific-transcript-35Ba, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding - 40210 1323.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 CG7298 CG7298 - - GO:0030247//polysaccharide binding GO:0006022 10178926 669.00 0.42 0.67 0.673771767679012 Up 0.153711530841368 CG42682 CG42682 - - - - 40039 1144.00 0.17 0.455 1.42033179894836 Up 0.190562673358869 Dic4 dicarboxylate carrier 4, isoform C K13577|1|9e-60|230|dmo:Dmoj_GI24334|mitochondrial dicarboxylate carrier GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 31504 2087.00 0.03 0.045 0.584962500721156 Up 0.047450799101836 CG42264 CG42264, isoform B K01298|1|2e-47|191|gga:416682|carboxypeptidase A2 [EC:3.4.17.15];K08780|3|6e-44|179|mdo:100017752|carboxypeptidase A3 [EC:3.4.17.1];K01300|4|1e-43|177|mdo:100016398|carboxypeptidase B2 [EC:3.4.17.20] - - - 38935 1584.00 1.045 0.75 -0.478540441585002 Down 0.159952450138687 Gr66a gustatory receptor 66a K08471|1|0.0|953|dme:Dmel_CG7189|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 42899 4622.00 4.905 4.33 -0.179886111492514 Down 0.182472592788271 CG5728 CG5728 K12867|1|6e-06|54.3|xtr:100216162|pre-mRNA-splicing factor SYF1 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0042254//ribosome biogenesis 42173 2102.15 5.655 6.805 0.267068137514174 Up 0.281732928278959 Arp5 Actin-related protein 5, isoform B K11672|1|0.0|1291|dme:Dmel_CG7940|actin-related protein 5 - - - 19835348 3432.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 - pre-mod(mdg4)-P - - - - 10178844 1266.00 0.12 0.205 0.772589503896928 Up 0.0972790912693171 CG42831 CG42831 - - - - 38084 1286.00 14.475 13.21 -0.131932881629771 Down 0.230055474838198 RabX6 RabX6, isoform B K07881|1|2e-23|110|bmy:Bm1_20650|Ras-related protein Rab-14;K07976|2|2e-23|110|dwi:Dwil_GK17190|Rab family, other;K07917|4|4e-23|109|ame:412030|Ras-related protein Rab-30;K07876|5|4e-23|109|spu:575255|Ras-related protein Rab-35 - GO:0016787//hydrolase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 37433 5317.98 24.75 21.285 -0.217591435072627 Down 0.373662660150575 CG42672 CG42672, isoform P K12460|1|0.0|2550|dme:Dmel_CG30387|ankyrin repeat-rich membrane spanning protein - - - 40205 7495.42 12.345 13.535 0.132768051072182 Up 0.224574032492405 CG42674 CG42674, isoform G K13744|1|1e-12|77.0|rno:310460|SH3 domain-containing guanine exchange factor;K12331|4|3e-12|75.9|cfa:490402|Rho guanine nucleotide exchange factor 11 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 14462853 518.74 1.15 2.05 0.833990048561071 Up 0.317131158367455 33429 1790.00 5.165 3.73 -0.469592718609822 Down 0.355402192576938 CG18641 CG18641 K01046|1|7e-33|141|tca:657679|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 49806 1198.00 13.395 14.6 0.124273787925001 Up 0.217177387399287 Spn38F serpin 38F, isoform B K13963|1|0.0|728|dme:Dmel_CG9334|serpin B - GO:0004866//endopeptidase inhibitor activity - 35435 2342.00 0.865 1.12 0.37272669442088 Up 0.144762911108176 CG2528 CG2528 K01322|1|0.0|1504|dme:Dmel_CG2528|prolyl oligopeptidase [EC:3.4.21.26] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39470 1177.00 0.49 1.16 1.24327115101236 Up 0.295172368247259 CG10749 CG10749 K00026|1|0.0|649|dme:Dmel_CG10749|malate dehydrogenase [EC:1.1.1.37] GO:0031980 GO:0016615//malate dehydrogenase activity GO:0009060//aerobic respiration;GO:0043648//dicarboxylic acid metabolic process;GO:0006007//glucose catabolic process 246500 1529.00 0.52 0.635 0.288244968631074 Up 0.0960903447364945 CG30177 CG30177 K11449|1|6e-06|52.4|cfa:474695|jumonji domain-containing protein 1 [EC:1.14.11.-] - - - 35057 1051.00 9.65 8.965 -0.106225359287068 Down 0.170056795667679 CG5131 CG5131 - - - - 35382 810.69 7.895 9.81 0.313313870359001 Up 0.362435609562805 Mpp6 M-phase phosphoprotein 6, isoform B K12593|1|4e-79|294|dme:Dmel_CG9250|M-phase phosphoprotein 6, animal type - GO:0030580//quinone cofactor methyltransferase activity GO:0006743//ubiquinone metabolic process 14462770 919.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 32058 950.00 19.47 69.125 1.82795469128914 Up 0.767732135781271 antdh antdh K11166|1|5e-21|101|mmu:216820|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 35118 1921.06 46.86 46.29 -0.0176563915712442 Down 0.084070796460177 CG31751 CG31751, isoform C - - - - 10178900 631.00 0.955 1.135 0.249119659255166 Up 0.108638224805178 CG42758 CG42758 - - - - 38148 2075.61 29.37 28.85 -0.0257719467920062 Down 0.0974111742174085 CG2277 CG2277, isoform C K13702|1|7e-23|109|xtr:100135182|abhydrolase domain-containing protein 10;K11757|2|8e-18|92.4|ecb:100051687|protein polybromo-1;K01081|3|1e-16|88.6|dme:Dmel_CG32549|5'-nucleotidase [EC:3.1.3.5] - - - 32138 1665.00 3.52 4.88 0.471305718925589 Up 0.347510236428477 Cyp28c1 Cyp28c1, isoform B K00517|1|0.0|991|dme:Dmel_CG1895| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 32389 1012.00 0.12 0.045 -1.41503749927884 Down 0.0997556465460309 betaNACtes4 betaNACtes4 K01527|1|1e-10|67.0|bfo:BRAFLDRAFT_131258|nascent polypeptide-associated complex subunit beta - - - 19834973 518.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 3772243 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 44315 2003.00 0.805 0.96 0.254045622606539 Up 0.103321886144499 pie pineapple eye, isoform B - - GO:0046914//transition metal ion binding - 43916 7172.68 9.415 8.29 -0.183588993118478 Down 0.247226258090081 rok Rho kinase, isoform D K04514|1|0.0|2508|dme:Dmel_CG9774|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0043169//cation binding;GO:0019899//enzyme binding GO:0007265//Ras protein signal transduction;GO:0065008;GO:0051017//actin filament bundle assembly;GO:0007052//mitotic spindle organization;GO:0007389//pattern specification process;GO:0051301//cell division;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0001736//establishment of planar polarity;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007281//germ cell development;GO:0000090//mitotic anaphase;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007476//imaginal disc-derived wing morphogenesis 50042 402.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 - CG14310 - - - - 3772141 140.00 0.01 0.555 5.79441586635011 Up 0.38171971998415 2768714 2345.00 0.15 0.225 0.584962500721156 Up 0.0898494254391758 Ir41a ionotropic receptor 41a K05206|1|2e-08|61.2|xtr:100125089|glutamate receptor, ionotropic, delta 1 GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 34673 3449.24 1.745 2.15 0.301109623379808 Up 0.174283450006604 pdm2 POU domain protein 2, isoform D K09364|1|0.0|1297|dsi:Dsim_GD23847|POU domain transcription factor, class 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0014016//neuroblast differentiation;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 36961 2130.92 1.565 1.815 0.213806891063132 Up 0.123464535728437 mthl3 methuselah-like 3, isoform C K04599|1|0.0|1016|dme:Dmel_CG6530|G protein-coupled receptor Mth (Methuselah protein) - - - 40909 2123.00 50.585 34.85 -0.537550989027066 Down 0.622407872143706 alpha-Est1 alpha-Esterase-1 K01044|1|0.0|1175|dme:Dmel_CG1031|carboxylesterase [EC:3.1.1.1];K03927|2|0.0|1145|dse:Dsec_GM10467|carboxylesterase type B [EC:3.1.1.1];K01066|5|1e-151|536|dme:Dmel_CG1121|esterase / lipase [EC:3.1.1.-] - GO:0004091//carboxylesterase activity - 42939 1655.00 7.87 7.275 -0.11341638771184 Down 0.159853387927619 Ppox protoporphyrinogen oxidase K00231|1|0.0|937|dsi:Dsim_GD18277|protoporphyrinogen oxidase [EC:1.3.3.4] GO:0019866//organelle inner membrane GO:0016634 GO:0006779//porphyrin-containing compound biosynthetic process 36603 1200.80 48.305 47.675 -0.0189395901060798 Down 0.0850614185708625 CG17385 CG17385, isoform B K09228|1|3e-41|169|api:100159445|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 36648 749.38 112.145 57.715 -0.958347073158823 Down 0.719092590146612 CG10200 hase und igel, isoform B - - - - 45360 1694.00 0.25 0.08 -1.64385618977472 Down 0.147833839651301 shu shutdown K09572|1|0.0|833|dme:Dmel_CG4735|FK506-binding protein 6 [EC:5.2.1.8] GO:0044424//intracellular part - GO:0044267//cellular protein metabolic process 33318 746.00 0.06 0.065 0.115477217419936 Up 0.0441487253995509 CG5440 CG5440, isoform C K06689|1|6e-87|318|dme:Dmel_CG5440|ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0010876//lipid localization 38231 8222.29 75.44 86.32 0.19436518881292 Up 0.396380927222296 alpha-Spec alpha spectrin, isoform D K06114|1|0.0|4662|dme:Dmel_CG1977|spectrin alpha GO:0043231//intracellular membrane-bounded organelle;GO:0030864//cortical actin cytoskeleton;GO:0044459//plasma membrane part;GO:0045202//synapse GO:0046872//metal ion binding;GO:0015631//tubulin binding GO:0007155//cell adhesion;GO:0016044//cellular membrane organization;GO:0007269//neurotransmitter secretion;GO:0016198//axon choice point recognition;GO:0008283//cell proliferation;GO:0007015//actin filament organization;GO:0007019//microtubule depolymerization;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007293//germarium-derived egg chamber formation 44791 1674.65 341.33 324.02 -0.0750843550057353 Down 0.223253203011491 Ef1gamma Ef1gamma, isoform C K03233|1|0.0|765|dme:Dmel_CG11901|elongation factor EF-1 gamma subunit GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0048102//autophagic cell death 5740854 2214.00 1.495 1.365 -0.131244533278253 Down 0.0851274600449082 CG34409 CG34409 K03992|1|1e-26|121|dre:100002060|mannan-binding lectin serine protease 1 [EC:3.4.21.-];K01362|2|3e-26|120|dpo:Dpse_GA18526| [EC:3.4.21.-];K03993|4|9e-23|108|oaa:100079601|mannan-binding lectin serine protease 2 [EC:3.4.21.104];K08664|5|7e-22|105|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31451 2319.00 4.885 5.39 0.14192671078412 Up 0.162660150574561 XRCC1 XRCC1 K10803|1|0.0|977|dme:Dmel_CG4208|DNA-repair protein XRCC1 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding GO:0006284//base-excision repair 41433 1462.07 47.155 44.11 -0.0963049922890464 Down 0.238277638356888 CG6950 CG6950, isoform D K08079|1|7e-124|444|dre:393315|cysteine-S-conjugate beta-lyase [EC:4.4.1.13];K00816|2|5e-116|417|rno:311844|kynurenine-oxoglutarate transaminase [EC:2.6.1.7];K00834|2|5e-116|417|rno:311844|glutamine-phenylpyruvate transaminase [EC:2.6.1.64] - GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity;GO:0016769//transferase activity, transferring nitrogenous groups GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 32969 1398.09 27.82 27.1 -0.0378295683010051 Down 0.116398098005547 Arp10 Actin-related protein 10, isoform B K05692|1|3e-17|89.7|mcc:713687|actin beta/gamma 1 GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity - 318168 977.00 0.165 0.535 1.69707286704269 Up 0.229163914938581 CG32718 CG32718, isoform D - - - - 37974 1207.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG3650 CG3650 K01312|1|2e-31|135|dme:Dmel_CG18211|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33839 2344.76 13.21 13.24 0.00327265556038984 Up 0.0427618544445912 Gal beta galactosidase, isoform B K12309|1|0.0|1340|dme:Dmel_CG9092|beta-galactosidase [EC:3.2.1.23] GO:0000323//lytic vacuole GO:0043167//ion binding;GO:0015925 GO:0044238//primary metabolic process 40925 1311.42 44.25 31.935 -0.470539004684272 Down 0.590212653546427 CG31472 CG31472, isoform B K00275|1|2e-139|495|dme:Dmel_CG31472|pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] - GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0000166//nucleotide binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0000166//nucleotide binding GO:0008614//pyridoxine metabolic process;GO:0008614//pyridoxine metabolic process 37843 3133.43 28.65 31.49 0.136358618491143 Up 0.290351340641923 sei seizure, isoform C K05322|1|0.0|1581|dme:Dmel_CG3182|potassium voltage-gated channel Eag-related subfamily H, invertebrate;K04905|2|0.0|647|mdo:100017968|potassium voltage-gated channel Eag-related subfamily H member 2;K04909|5|0.0|644|tgu:100220710|potassium voltage-gated channel Eag-related subfamily H member 6 GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part GO:0060089;GO:0005267//potassium channel activity;GO:0060089;GO:0005267//potassium channel activity GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0030001//metal ion transport;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0030001//metal ion transport 34544 2308.00 5.415 6.29 0.216098679270962 Up 0.235702020869106 CG6201 CG6201 K01217|1|0.0|1276|dme:Dmel_CG6201|L-iduronidase [EC:3.2.1.76] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0009653//anatomical structure morphogenesis;GO:0044238//primary metabolic process 44620 1349.00 55.56 25.8 -1.10667553367078 Down 0.719356756042795 CG14630 CG14630 K00471|1|2e-117|422|dpo:Dpse_GA18803|gamma-butyrobetaine dioxygenase [EC:1.14.11.1] - GO:0003824//catalytic activity GO:0008152//metabolic process 3771847 145.00 0.43 0.01 -5.4262647547021 Down 0.33109893012812 14462447 1148.00 0.07 0.155 1.14684138832927 Up 0.0982366926429798 33493 861.00 11.35 10.935 -0.0537390771301842 Down 0.110025095760137 Prx6005 peroxiredoxin 6005 K11188|1|1e-126|452|dme:Dmel_CG3083|peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-] GO:0044444//cytoplasmic part GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0019725//cellular homeostasis 34958 665.00 0.9 0.87 -0.0489096004809462 Down 0.0483423590014529 CG17329 CG17329 K08849|1|3e-07|55.1|gga:415684|mixed lineage kinase domain-like [EC:2.7.11.1] - GO:0046872//metal ion binding - 31731 2114.50 4.31 4.04 -0.0933325763373035 Down 0.105732399947167 CG1575 CG1575, isoform B - - - - 14462449 976.00 1.19 1.055 -0.173718574600758 Down 0.0919627526086382 39567 2335.00 0.68 0.86 0.338801913451759 Up 0.119171839915467 Sox21a Sox21a, isoform B K09267|1|6e-89|328|dme:Dmel_CG7345|transcription factor SOX1/2/3/14/21 (SOX group B) GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - 32635 632.79 551.08 524.645 -0.0709202131373384 Down 0.204431382908467 RpS19a ribosomal protein S19a, isoform E K02966|1|3e-86|318|dsi:Dsim_GD17290|small subunit ribosomal protein S19e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression 41111 873.00 2.545 3.335 0.39002110510889 Up 0.260500594373266 CG16749 CG16749 K01312|1|7e-22|104|dpo:Dpse_GA11599|trypsin [EC:3.4.21.4];K01324|5|1e-18|93.6|bta:533547|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 48336 746.00 33.835 37.705 0.156239461124167 Up 0.325584467045304 GstD3 glutathione S transferase D3 K00799|1|4e-114|410|dme:Dmel_CG4381|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity - 5740513 4015.75 13.29 17.89 0.428812282775734 Up 0.504292695812971 CG34420 CG44837, isoform E K01273|1|0.0|1170|dme:Dmel_CG34420|membrane dipeptidase [EC:3.4.13.19] - GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process 44268 1592.00 0.36 0.505 0.488286481309482 Up 0.111742174085326 sut3 sugar transporter 3, isoform B K07299|1|2e-64|246|spu:590274|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1;K08142|2|5e-59|228|xla:379400|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3 GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity GO:0006810//transport 32770 1501.27 17.64 17.115 -0.0435892685476826 Down 0.10890239070136 CG6769 CG6769, isoform B K09506|1|6e-06|52.4|nvi:100118085|DnaJ homolog subfamily A member 5 GO:0044464//cell part GO:0046914//transition metal ion binding - 3355126 2095.08 63.465 65.325 0.0416740331298768 Up 0.130927222295602 CG17493 CG17493, isoform D K10840|1|4e-66|252|mdo:100026359|centrin-2 GO:0043232 GO:0046872//metal ion binding;GO:0042623//ATPase activity, coupled;GO:0032559 - 38056 2133.00 1.925 1.635 -0.235567810084181 Down 0.136870954959715 mthl9 methuselah-like 9 K04599|1|4e-31|136|dme:Dmel_CG6530|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0010259//multicellular organismal aging 39164 3858.00 3.63 3.7 0.0275557225205616 Up 0.0565975432571655 Taf2 TBP-associated factor 2, isoform B K03128|1|0.0|2305|dme:Dmel_CG6711|transcription initiation factor TFIID subunit D2 GO:0005667//transcription factor complex GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 34064 3264.00 13.675 12.045 -0.183106439441448 Down 0.282657508915599 LKR lysine ketoglutarate reductase, isoform B K00290|1|0.0|1869|dme:Dmel_CG7144|saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7];K00291|4|0.0|945|mmu:30956|saccharopine dehydrogenase (NADP+, L-lysine forming) [EC:1.5.1.8];K00292|4|0.0|945|mmu:30956|saccharopine dehydrogenase (NAD+, L-glutamate forming) [EC:1.5.1.9] - GO:0003824//catalytic activity GO:0008152//metabolic process 40225 5099.00 4.855 5.485 0.176020324984001 Up 0.191817461365738 gogo golden goal K04659|1|3e-13|79.0|dre:794881|thrombospondin;K08623|4|3e-11|72.0|tgu:100217683|a disintegrin and metalloproteinase with thrombospondin motifs 8 [EC:3.4.24.-] GO:0043005//neuron projection;GO:0031224//intrinsic to membrane;GO:0030427//site of polarized growth GO:0004871//signal transducer activity GO:0006935//chemotaxis 12798328 412.14 2.425 2.52 0.0554389864254266 Up 0.0667679302602034 CG43272 CG43272, isoform B - - - - 19835289 672.00 0.675 0.425 -0.667424660913129 Down 0.153711530841368 31119 829.00 26.695 26.69 -0.000270243522545337 Down 0.0401862369568089 CG3740 CG3740 - - - - 19835851 1105.00 0.29 0.305 0.0727563424353138 Up 0.042365605600317 19835226 876.00 0.095 0.155 0.70626879694329 Up 0.0806696605468234 42478 1715.68 37.08 28.825 -0.363320636086397 Down 0.525525029718663 CG5630 hadley, isoform C - - - - 42954 5119.00 5.92 6.45 0.123701984681667 Up 0.157541936336019 polybromo polybromo K11757|1|0.0|2795|dme:Dmel_CG11375|protein polybromo-1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0003006//developmental process involved in reproduction 19836230 411.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 31371 2383.00 0.645 0.91 0.496567384775442 Up 0.15153216219786 CG15572 CG15572 - - - - 37019 2736.22 15.61 16.15 0.0490636276033785 Up 0.118709549597147 CG6406 CG6406, isoform B - - - - 31954 1840.67 0.59 0.51 -0.210217707390346 Down 0.0766411306300357 Ipod interaction partner of Dnmt2, isoform C - - - - 34376 882.00 1.385 1.755 0.341585054255372 Up 0.172203143574165 trk trunk - - GO:0005102//receptor binding GO:0008595//anterior/posterior axis specification, embryo;GO:0045595//regulation of cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 38799 941.00 7.215 6.895 -0.0654488429772179 Down 0.107680623431515 MED4 mediator complex subunit 4 - GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 37654 3453.00 2.135 1.86 -0.198933448512459 Down 0.127757231541408 CG42741 CG42741 K09212|1|2e-99|363|dme:Dmel_CG9895|krueppel-like factor, other GO:0044464//cell part GO:0046914//transition metal ion binding - 39975 1694.00 0.56 0.68 0.280107919192735 Up 0.0949346189406948 Adgf-B adenosine deaminase-related growth factor B K01488|1|0.0|1034|dme:Dmel_CG5998|adenosine deaminase [EC:3.5.4.4] GO:0044421//extracellular region part GO:0005102//receptor binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0009127//purine nucleoside monophosphate biosynthetic process 41178 2784.00 20.295 0.21 -6.59459120191893 Down 0.903348302734117 Unc-115b Unc-115b, isoform E K07520|1|0.0|1450|dme:Dmel_CG31352|actin-binding LIM protein GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization 41139 1444.00 7.52 6.57 -0.194839291355308 Down 0.2342491084401 Rlb1 Rlb1 - - - - 19835039 682.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 32180 2187.00 0.02 0.195 3.28540221886225 Up 0.175009906221107 CG1924 CG1924 K08054|1|0.0|743|dsi:Dsim_GD17820|calnexin GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process 39586 1200.00 0.2 0.04 -2.32192809488736 Down 0.151135913353586 CG4613 CG4613, isoform C K01312|1|1e-42|173|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|2|2e-42|172|ssc:397144|plasma kallikrein [EC:3.4.21.34];K09634|4|2e-41|169|cfa:610987|transmembrane protease, serine 3 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40217 3681.00 3.475 4.725 0.443301351497565 Up 0.330933826443006 Su(var)3-3 suppressor of variegation 3-3, isoform C K11450|1|0.0|1661|dme:Dmel_CG17149|lysine-specific histone demethylase 1 [EC:1.-.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0030554//adenyl nucleotide binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0030554//adenyl nucleotide binding;GO:0043565//sequence-specific DNA binding GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021536//diencephalon development;GO:0031328//positive regulation of cellular biosynthetic process;GO:0006482//protein demethylation;GO:0043009//chordate embryonic development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021536//diencephalon development;GO:0031328//positive regulation of cellular biosynthetic process;GO:0006482//protein demethylation;GO:0043009//chordate embryonic development 12798288 3528.00 22.625 26.28 0.216047483464399 Up 0.378153480385682 33965 2529.43 15.5 19.675 0.344095420233249 Up 0.464337604015322 wee Wee1 ortholog, isoform B K06632|1|0.0|1221|dme:Dmel_CG4488|wee1-like protein kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0000075//cell cycle checkpoint;GO:0051640//organelle localization;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0007067//mitosis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process 50073 1583.00 50.78 55.26 0.121975167164986 Up 0.278331792365606 CG13631 CG13631, isoform B - - - - 5740622 1022.00 0.155 0.175 0.175086706558091 Up 0.0511161009113723 CG34426 CG34426 - - GO:0030247//polysaccharide binding GO:0006022 42072 1085.00 0.18 0.21 0.222392421336448 Up 0.0573900409457139 CG5246 CG5246 K11997|1|2e-36|152|ame:409206|tripartite motif-containing protein 2/3;K09633|2|1e-35|150|mmu:50528|transmembrane protease, serine 2 [EC:3.4.21.-] - - - 42159 1549.00 1.455 1.43 -0.0250040061298944 Down 0.0445449742438251 CG7794 CG7794 K07374|1|1e-131|470|bmy:Bm1_38680|tubulin alpha - - - 37290 1034.02 8.885 4.405 -1.01222975710826 Down 0.585919957733457 mus209 proliferating cell nuclear antigen, isoform B K04802|1|6e-137|486|dya:Dyak_GE13815|proliferating cell nuclear antigen - - - 44433 1652.00 19.935 17.13 -0.218778453913332 Down 0.357680623431515 Hs2st heparan sulfate 2-O-sulfotransferase K02513|1|0.0|729|dme:Dmel_CG10234|heparan sulfate 2-O-sulfotransferase HS2ST1 [EC:2.8.2.-] GO:0031224//intrinsic to membrane GO:0034483//heparan sulfate sulfotransferase activity GO:0060541//respiratory system development;GO:0005975//carbohydrate metabolic process;GO:0023060 3355109 3112.00 16.215 17.175 0.082981075249656 Up 0.168042530709285 Parp Poly-(ADP-ribose) polymerase K10798|1|0.0|1967|dme:Dmel_CG40411|poly [ADP-ribose] polymerase [EC:2.4.2.30] GO:0031981//nuclear lumen;GO:0005700//polytene chromosome;GO:0000790//nuclear chromatin GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0016763//transferase activity, transferring pentosyl groups GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0051276//chromosome organization;GO:0032507//maintenance of protein location in cell;GO:0008380//RNA splicing;GO:0006997//nucleus organization;GO:0006464//cellular protein modification process;GO:0034605//cellular response to heat;GO:0002780 44448 7923.23 32.975 33.96 0.0424637994141314 Up 0.122440892880729 scrib scribbled, isoform U K12796|1|5e-106|386|xtr:780049|erbb2-interacting protein GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0044444//cytoplasmic part;GO:0045202//synapse GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle;GO:0032989;GO:0008354//germ cell migration;GO:0007043//cell-cell junction assembly;GO:0045570//regulation of imaginal disc growth;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0045137//development of primary sexual characteristics;GO:0007635//chemosensory behavior;GO:0008285//negative regulation of cell proliferation;GO:0001736//establishment of planar polarity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0007560//imaginal disc morphogenesis;GO:0002780;GO:0007049//cell cycle 43277 3340.03 33.375 34.755 0.0584527081236992 Up 0.159093910976093 CG31064 CG31064, isoform G K12482|1|3e-93|343|bta:528153|RUN and FYVE domain-containing protein 1 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis 43803 4286.49 59.01 62.785 0.0894604668546107 Up 0.226489235239731 Eph Eph receptor tyrosine kinase, isoform F K05110|1|0.0|2018|dme:Dmel_CG1511|Eph receptor B1 [EC:2.7.10.1] GO:0016021//integral to membrane GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559 GO:0023060;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006351//transcription, DNA-dependent;GO:0006464//cellular protein modification process 34354 2205.00 32.01 33.605 0.070153226910446 Up 0.175439175802404 CG5734 CG5734 - - GO:0005543//phospholipid binding GO:0009987//cellular process 41010 2106.12 0.175 0.24 0.45567948377619 Up 0.0784572711662924 CG31259 CG31259, isoform B K02354|1|1e-20|101|spu:583340|frizzled 4 - - - 37514 1609.03 42.81 44.91 0.0690888865826532 Up 0.182208426892088 CG11474 CG11474, isoform C - - - - 32570 1906.00 0.18 0.545 1.59825932333461 Up 0.224673094703474 CG12698 CG12698 - - - - 38362 1586.00 40.44 34.71 -0.220431632074368 Down 0.404272883370757 scramb2 scramblase 2 - - GO:0005548//phospholipid transporter activity GO:0007267//cell-cell signaling 39969 657.00 55.585 67.45 0.279122829024412 Up 0.487320036983225 CG7484 CG7484 - GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0019725//cellular homeostasis 37633 3529.06 52.165 62.925 0.270551153291791 Up 0.474673094703474 PIP5K59B PIP5K59B, isoform I K00889|1|0.0|1077|dpo:Dpse_GA25087|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] - GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0030384;GO:0006796//phosphate-containing compound metabolic process;GO:0030384;GO:0006796//phosphate-containing compound metabolic process;GO:0030384;GO:0006796//phosphate-containing compound metabolic process 35509 3847.45 17.89 19.725 0.140871912848913 Up 0.26367058512746 ap apterous, isoform E K09373|1|1e-154|547|dsi:Dsim_GD10352|LIM homeobox protein 2/9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0048869//cellular developmental process;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0035110;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0048869//cellular developmental process;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0035110;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0048869//cellular developmental process;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0035110;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0048869//cellular developmental process;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0035110;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006351//transcription, DNA-dependent 40150 2240.36 267.13 90.805 -1.55669836274994 Down 0.771364416853784 serp serpentine, isoform C K04550|1|3e-07|57.8|gga:396170|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor);K06233|2|3e-07|57.8|ecb:100062836|low density lipoprotein-related protein 2 GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0030247//polysaccharide binding GO:0035151//regulation of tube size, open tracheal system;GO:0006022 32473 6481.00 2.335 2.365 0.0184176336297334 Up 0.046559239202219 shtd shattered K03348|1|0.0|3814|dme:Dmel_CG9198|anaphase-promoting complex subunit 1 GO:0044464//cell part GO:0046914//transition metal ion binding - 14462502 1122.00 0.08 0.355 2.14974711950468 Up 0.197728173292828 35075 637.00 0.165 0.565 1.77578484305673 Up 0.240423986263373 CG42635 CG42635, isoform B - - - - 35919 1933.00 0.845 1.165 0.463306708372096 Up 0.168174613657377 CG13741 CG13741 - - - - 42370 1150.00 7.7 6.66 -0.209336268511001 Down 0.250396248844274 Surf6 surfeit 6 - - GO:0051184 GO:0043623//cellular protein complex assembly;GO:0022613//ribonucleoprotein complex biogenesis 31809 1586.40 35.495 26.655 -0.413209631733985 Down 0.550950997226258 CG2004 CG2004, isoform G - - - - 36803 708.00 0.895 1.125 0.329965413952781 Up 0.132908466516973 CG3687 CG3687 - - - - 14462691 566.00 0.01 0.175 4.12928301694497 Up 0.187062475234447 40275 1515.00 0.515 1.955 1.92452427012413 Up 0.445251618016114 CG17637 CG17637 K08214|1|2e-06|54.3|bta:504885|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18 GO:0031224//intrinsic to membrane GO:0008493//tetracycline transporter activity GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus 43580 5592.53 34.41 30.425 -0.17757062913589 Down 0.347939506009774 sima similar, isoform D K08268|1|0.0|730|dme:Dmel_CG7951|hypoxia-inducible factor 1 alpha GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0060089;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0033554//cellular response to stress;GO:0023060;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0033554//cellular response to stress;GO:0023060 34818 2574.45 2.08 3.2 0.62148837674627 Up 0.333377360982697 nimC2 nimrod C2, isoform C K06252|1|2e-39|164|hsa:3371|tenascin - - - 35766 1253.00 28.27 14.09 -1.00460027152154 Down 0.683694360058116 Odc1 ornithine decarboxylase 1 K01581|1|0.0|775|dme:Dmel_CG8721|ornithine decarboxylase [EC:4.1.1.17] - GO:0016831//carboxy-lyase activity GO:0006595//polyamine metabolic process 37030 569.00 0.995 1.51 0.60178011878143 Up 0.223847576277903 CG14488 CG14488 - - - - 42287 5461.00 0.535 0.925 0.789914474115165 Up 0.206016378285563 CG6026 CG6026 - - - - 19835760 433.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 35915 2819.00 0.835 0.875 0.0675068193582768 Up 0.0525359926033549 CNT1 concentrative nucleoside transporter 1 K11536|1|1e-115|417|dya:Dyak_GE19248|pyrimidine nucleoside transport protein - - - 19835568 319.00 0.285 0.01 -4.83289001416474 Down 0.263802668075551 34645 1071.00 26.43 17.725 -0.576390797514691 Down 0.599458459912825 CG6583 CG6583 - - - - 36233 1356.00 23.405 28.105 0.264010049862964 Up 0.423490952318056 CG30022 CG30022 K01069|1|6e-19|95.5|tad:TRIADDRAFT_20939|hydroxyacylglutathione hydrolase [EC:3.1.2.6] - GO:0003824//catalytic activity;GO:0005488//binding - 317823 3594.19 99.33 125.765 0.340429064058792 Up 0.55514463082816 CG32017 CG32017, isoform D - - - - 42474 526.00 0.24 0.11 -1.12553088208386 Down 0.122407872143706 TotB turandot B - GO:0044421//extracellular region part - GO:0051707//response to other organism;GO:0009416//response to light stimulus;GO:0006952//defense response;GO:0009605//response to external stimulus 31610 2305.07 13.695 13.73 0.00368235944172234 Up 0.0434552899220711 CG14440 CG14440, isoform B - - - - 33058 1466.50 2.29 2.625 0.196969824456541 Up 0.144267600052833 hydra hydra, isoform J - - - - 31294 963.00 0.75 0.835 0.154885601978171 Up 0.0742636375643904 Fcp3C follicle cell protein 3C - - - - 36864 1551.00 0.03 0.085 1.50250034052918 Up 0.0866464139479593 Nach nach, isoform C K04832|1|2e-25|117|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04827|2|3e-18|93.2|xla:373658|nonvoltage-gated sodium channel 1 gamma;K04831|3|5e-18|92.8|dre:407668|amiloride-sensitive cation channel 4, pituitary;K04829|4|5e-17|89.4|mcc:713320|amiloride-sensitive cation channel 2, neuronal - - - 43060 1408.00 9.955 4.675 -1.0904549509455 Down 0.610124157971206 CG31370 CG31370 - - - - 37768 2163.00 4.425 4.995 0.174807222822058 Up 0.180062078985603 CG5543 CG5543 K02208|1|5e-97|355|bmy:Bm1_33825|cyclin-dependent kinase 8/11 [EC:2.7.11.22];K12857|2|3e-12|73.9|mdo:100027017|Prp8 binding protein - - - 38523 2487.00 20.26 20 -0.0186341741390509 Down 0.0738343679830934 CG1311 CG1311, isoform B K06515|1|0.0|1204|dme:Dmel_CG1311|CDW92 antigen GO:0031224//intrinsic to membrane - - 39391 1539.90 460.325 277.645 -0.729411381437343 Down 0.703605864482895 CG6910 CG6910, isoform C K00469|1|2e-169|595|dme:Dmel_CG6910|inositol oxygenase [EC:1.13.99.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0006020//inositol metabolic process 36917 1790.00 0.11 0.12 0.125530882083859 Up 0.0444459120327566 CG9642 CG9642 K11848|1|1e-17|91.3|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15];K11426|2|6e-11|68.9|mmu:69726|SET and MYND domain-containing protein - - - 261629 3463.50 66.6 50.295 -0.405107193443684 Down 0.578226126007133 Unc-115a Unc-115a, isoform I K07520|1|0.0|1450|dme:Dmel_CG31352|actin-binding LIM protein GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization;GO:0051234//establishment of localization;GO:0006996//organelle organization 8673961 412.00 0.01 0.69 6.10852445677817 Up 0.423094703473782 CG42580 CG42580 - - - - 34532 1716.00 0.045 0.055 0.289506617194985 Up 0.0467903843613789 CG14913 CG14913 - - - - 41832 682.00 8.43 6.565 -0.360737620049195 Down 0.374389116365077 CG4210 CG4210 K00657|1|7e-54|209|dwi:Dwil_GK11862|diamine N-acetyltransferase [EC:2.3.1.57] - - - 39479 1472.03 60.835 69.605 0.194289360727583 Up 0.390965526350548 CG11255 adenosine kinase, isoform C K00856|1|0.0|660|dme:Dmel_CG11255|adenosine kinase [EC:2.7.1.20] - GO:0019206//nucleoside kinase activity;GO:0019206//nucleoside kinase activity GO:0043101//purine-containing compound salvage;GO:0043101//purine-containing compound salvage 42086 2980.50 37.23 40.76 0.130688435314301 Up 0.286884163254524 beat-IIa beaten path IIa, isoform B - - - - 318714 981.00 0.2 0.31 0.632268215499513 Up 0.102397305507859 CG31404 CG31404 K11665|1|4e-52|204|dwi:Dwil_GK13479|DNA helicase INO80 [EC:3.6.1.-] - - - 34126 1812.21 46.845 39.48 -0.246773080285332 Down 0.441619336943601 Snx6 sorting nexin 6, isoform B - - GO:0005543//phospholipid binding GO:0009987//cellular process 14462597 238.00 1 1.205 0.269033146455237 Up 0.11966715097081 CG43789 CG43789 - - - - 31913 3714.69 3.405 2.965 -0.199622693466068 Down 0.163980980055475 Sp1 Sp1, isoform F K09199|1|3e-70|267|bfo:BRAFLDRAFT_123392|transcription factor Sp9;K09198|3|7e-67|256|bta:784504|transcription factor Sp8 - GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0005488//binding GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 42379 2893.00 0.25 0.245 -0.0291463456595165 Down 0.0416391493858143 mira miranda, isoform C K10362|1|1e-14|82.8|hsa:399687|myosin XVIII GO:0044448//cell cortex part;GO:0005819//spindle;GO:0044448//cell cortex part;GO:0005819//spindle GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0048699//generation of neurons;GO:0006403//RNA localization;GO:0044087;GO:0008105//asymmetric protein localization;GO:0001709//cell fate determination;GO:0000578//embryonic axis specification;GO:0007292//female gamete generation;GO:0006508//proteolysis;GO:0048699//generation of neurons;GO:0006403//RNA localization;GO:0044087;GO:0008105//asymmetric protein localization;GO:0001709//cell fate determination;GO:0000578//embryonic axis specification;GO:0007292//female gamete generation;GO:0006508//proteolysis 19835761 810.00 2.4 0.01 -7.90689059560852 Down 0.700799101835953 41839 8416.00 2.7 2.7 0 - 0.0382380134724607 tefu telomere fusion K04728|1|0.0|5448|dme:Dmel_CG6535|ataxia telangectasia mutated family protein [EC:2.7.11.1] - - - 41968 575.00 14.435 13.46 -0.100892697625665 Down 0.185807687227579 mtSSB mitochondrial single stranded DNA-binding protein K03111|1|2e-75|280|dme:Dmel_CG4337|single-strand DNA-binding protein - - - 8674055 16585.92 13.785 9.79 -0.493718502406496 Down 0.504788006868313 mgl megalin, isoform E K06233|1|0.0|8973|dpo:Dpse_GA11430|low density lipoprotein-related protein 2 GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046872//metal ion binding GO:0006629//lipid metabolic process 35240 810.00 25.1 22.09 -0.18429394548286 Down 0.332221635186897 CG10166 CG10166 K00721|1|1e-137|488|dme:Dmel_CG10166|dolichol-phosphate mannosyltransferase [EC:2.4.1.83] GO:0031090//organelle membrane GO:0000030//mannosyltransferase activity GO:0006497//protein lipidation;GO:0006493//protein O-linked glycosylation 19836153 288.00 0.9 0.56 -0.684498174272071 Down 0.183364152687888 41125 1727.00 25.635 27.2 0.0854917537404062 Up 0.199808479725267 Task7 TWIK-related acid-sensitive K[+] channel 7 K05323|1|9e-103|374|nvi:100120322|potassium channel subfamily K, invertebrate GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 42682 1872.00 7.35 5.85 -0.32930762525296 Down 0.335985999207502 Cyp6d4 Cyp6d4 K00517|1|0.0|1006|dme:Dmel_CG12800| [EC:1.14.-.-];K07424|5|1e-82|307|der:Dere_GG23366|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 37498 1776.00 0.045 0.075 0.736965594166206 Up 0.0626403381323471 CG34369 pickpocket 9, isoform B - GO:0044464//cell part GO:0005261//cation channel activity GO:0030001//metal ion transport 50396 316.00 3.755 3.175 -0.242056315854743 Down 0.196638488971074 CG15036 CG15036 - - - - 38748 4128.16 23.14 26.705 0.206721019784644 Up 0.368544445912033 velo veloren, isoform D K08595|1|2e-57|225|cin:100183329|sentrin-specific protease 6 [EC:3.4.22.-];K08596|3|3e-52|208|xla:100216311|sentrin-specific protease 7 [EC:3.4.22.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 19834910 411.00 0.01 0.235 4.55458885167764 Up 0.229362039360719 14462440 2025.00 0.075 0.025 -1.58496250072116 Down 0.081858407079646 35281 1063.30 149.185 220.52 0.563807021307152 Up 0.66114119667151 CG16772 CG16772, isoform B - - - - 33402 2333.58 75.725 70.905 -0.0948823076029287 Down 0.230484744419495 l(2)s5379 rotini, isoform E - GO:0005739//mitochondrion;GO:0044431//Golgi apparatus part;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0044431//Golgi apparatus part;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0044431//Golgi apparatus part;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0009967//positive regulation of signal transduction;GO:0007005//mitochondrion organization;GO:0009967//positive regulation of signal transduction;GO:0007005//mitochondrion organization;GO:0009967//positive regulation of signal transduction;GO:0007005//mitochondrion organization 35819 513.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 Lcp3 larval cuticle protein 3, isoform B - - GO:0042302//structural constituent of cuticle - 41736 981.00 0.16 0.225 0.491853096329674 Up 0.0788535200105666 CG14839 CG14839 - - - - 42562 909.00 1.35 1.53 0.180572245641821 Up 0.103090740985339 CG6800 CG6800 K08817|1|1e-63|243|nve:NEMVE_v1g236269|cell cycle related kinase [EC:2.7.11.22] GO:0044464//cell part GO:0004672//protein kinase activity;GO:0032559 GO:0048858//cell projection morphogenesis;GO:0006464//cellular protein modification process 117364 1507.00 0.18 0.145 -0.31194400631474 Down 0.0651499141460837 Hex-t1 Hex-t1 K00844|1|0.0|935|dme:Dmel_CG33102|hexokinase [EC:2.7.1.1] - GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559 GO:0006007//glucose catabolic process 318252 1059.00 36.105 53.495 0.567205411367065 Up 0.632941487253995 CG32857 CG32857 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0051540;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0031163 32961 1951.47 4.73 5.475 0.21101878114914 Up 0.215427288337076 CG14221 CG14221, isoform C - - - GO:0019725//cellular homeostasis 33454 994.00 0.16 0.01 -4 Down 0.178939373926826 CG15398 CG15398 K03120|1|5e-08|58.5|phu:Phum_PHUM375280|transcription initiation factor TFIID TATA-box-binding protein - GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0006352//DNA-dependent transcription, initiation 43395 1030.00 1.985 1.545 -0.361532169238583 Down 0.190331528199709 CG9997 CG9997, isoform B - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0048609//multicellular organismal reproductive process;GO:0045297//post-mating behavior 2768881 2263.96 52.615 61.6 0.22745619511766 Up 0.432439572051248 CG9132 CG9132, isoform C - GO:0012505//endomembrane system;GO:0030118//clathrin coat;GO:0012505//endomembrane system;GO:0030118//clathrin coat GO:0005488//binding;GO:0005488//binding GO:0016192//vesicle-mediated transport;GO:0016192//vesicle-mediated transport 45908 1633.00 127.275 113.955 -0.159484838524197 Down 0.360223220182274 nec necrotic K13963|1|3e-52|206|aag:AaeL_AAEL007765|serpin B - GO:0004866//endopeptidase inhibitor activity GO:0002376//immune system process;GO:0050832//defense response to fungus;GO:0006508//proteolysis;GO:0008592//regulation of Toll signaling pathway 12798369 377.00 0.81 0.765 -0.0824621601919728 Down 0.0531303658697662 CG43059 CG43059 - - - - 43445 1216.00 4.225 4.405 0.0601906777508669 Up 0.0826509047681944 CG14511 CG14511 - GO:0031224//intrinsic to membrane - GO:0006810//transport 43473 1090.29 10.515 6.115 -0.782024446204393 Down 0.561418570862502 CG2310 CG2310, isoform B - - - - 31793 3466.00 4.595 4.435 -0.0511307569879704 Down 0.0768722757891956 IntS4 integrator 4 K13141|1|0.0|1888|dme:Dmel_CG12113|integrator complex subunit 4 GO:0043234//protein complex GO:0005488//binding GO:0015031//protein transport 48481 3571.00 7.51 8.26 0.137328873905174 Up 0.193831726324132 l(1)dd4 Gamma-tubulin ring protein 91 K01769|1|3e-08|61.6|tca:657050|guanylate cyclase, other [EC:4.6.1.2] GO:0000930//gamma-tubulin complex GO:0008017//microtubule binding GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0007126//meiosis 34509 2093.00 0.895 1.44 0.686109224178056 Up 0.235305772024832 CG7309 CG7309 - GO:0044464//cell part GO:0005215//transporter activity GO:0030001//metal ion transport 38306 5187.98 78.16 103.48 0.404849586716356 Up 0.585754854048342 CG42669 CG45186, isoform Z K10369|1|8e-18|94.4|tca:664216|supervillin - GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0006996//organelle organization;GO:0006996//organelle organization;GO:0006996//organelle organization 34263 3328.62 35.235 39.215 0.154396386347832 Up 0.315579183727381 numb numb, isoform D K06057|1|0.0|862|dme:Dmel_CG3779|numb GO:0044448//cell cortex part;GO:0043231//intracellular membrane-bounded organelle;GO:0044448//cell cortex part;GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding;GO:0005102//receptor binding GO:0051960//regulation of nervous system development;GO:0016477//cell migration;GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0008593//regulation of Notch signaling pathway;GO:0008356//asymmetric cell division;GO:0033036;GO:0001708//cell fate specification;GO:0030100//regulation of endocytosis;GO:0007610//behavior;GO:0035051//cardiocyte differentiation;GO:0048699//generation of neurons;GO:0051960//regulation of nervous system development;GO:0016477//cell migration;GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0008593//regulation of Notch signaling pathway;GO:0008356//asymmetric cell division;GO:0033036;GO:0001708//cell fate specification;GO:0030100//regulation of endocytosis;GO:0007610//behavior;GO:0035051//cardiocyte differentiation;GO:0048699//generation of neurons 40608 10050.36 32.215 36.18 0.16745981319981 Up 0.337901201954828 Cdep Chondrocyte-derived ezrin-like domain containing protein ortholog, isoform G K06082|1|8e-87|322|tgu:100221501|FERM, RhoGEF and pleckstrin domain protein 2 GO:0043232;GO:0044425//membrane part;GO:0043232;GO:0044425//membrane part;GO:0043232 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008092//cytoskeletal protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008092//cytoskeletal protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 251645 744.44 200.335 180.835 -0.147740559116788 Down 0.350184916127328 CG32276 CG32276, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 19836152 1002.00 2.1 0.135 -3.95935801550265 Down 0.565414080042267 34983 1982.00 0.565 0.07 -3.01282404035758 Down 0.296063928146876 CG4580 CG4580 K01415|1|4e-20|99.8|nve:NEMVE_v1g229362|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|4e-20|99.8|mmu:27390|membrane metallo-endopeptidase-like 1;K09610|4|2e-16|87.4|xla:495020|endothelin-converting enzyme-like 1 [EC:3.4.24.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835128 4733.00 1.91 2.83 0.567229414796134 Up 0.299200898164047 32820 3203.00 39.965 36.585 -0.127484830379898 Down 0.285398230088496 betaCop coat protein (coatomer) beta K12392|1|2e-18|95.5|smm:Smp_034870|AP-1 complex subunit beta-1 GO:0030120//vesicle coat GO:0005488//binding GO:0006909//phagocytosis;GO:0019915//lipid storage;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 40357 1442.00 16.585 16.4 -0.016183197282576 Down 0.0677585523708889 CG7632 CG7632, isoform B K01175|1|2e-31|136|mmu:68607| [EC:3.1.-.-];K13703|2|1e-07|58.2|nvi:100122014|abhydrolase domain-containing protein 11 - - - 36950 1545.00 11.325 6.765 -0.74334921095706 Down 0.562343151499141 CG30101 CG30101 - - - - 41093 1525.00 0.285 0.335 0.233199176293031 Up 0.0666688680491349 CG11997 CG11997 - - - - 33626 2743.17 34.055 28.995 -0.232062493906324 Down 0.406221106855105 CG3714 CG3714, isoform H K00763|1|0.0|1272|dme:Dmel_CG3714|nicotinate phosphoribosyltransferase [EC:2.4.2.11] GO:0044444//cytoplasmic part GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019357//nicotinate nucleotide biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019357//nicotinate nucleotide biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019357//nicotinate nucleotide biosynthetic process;GO:0002164//larval development;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0006950//response to stress;GO:0048806//genitalia development;GO:0009790//embryo development;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019357//nicotinate nucleotide biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019357//nicotinate nucleotide biosynthetic process 318998 490.00 2.12 4.065 0.939191087511828 Up 0.453341698586712 CG42367 CG42367 - - - - 44291 1655.56 394.13 366.025 -0.106729377411482 Down 0.284242504292696 Idh isocitrate dehydrogenase, isoform K K00031|1|0.0|862|dse:Dsec_GM24945|isocitrate dehydrogenase [EC:1.1.1.42] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044262//cellular carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process 33107 3039.30 20.25 20.935 0.0479950100809527 Up 0.126601505745608 Dd dullard, isoform C K01090|1|1e-89|331|dre:492343|protein phosphatase [EC:3.1.3.16] GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process;GO:0006997//nucleus organization 8674082 643.00 3.595 3.675 0.031752479284429 Up 0.0585787874785365 CG42523 CG42523, isoform B - - - - 35910 2280.00 13.18 6.805 -0.953683303504057 Down 0.619072777704398 proPO45 prophenoloxidase 2 K00505|1|0.0|956|dme:Dmel_CG42640|tyrosinase [EC:1.14.18.1] - GO:0022892;GO:0003824//catalytic activity GO:0051234//establishment of localization 37261 2168.25 7.92 9.915 0.324112342149238 Up 0.371714436666226 isopeptidase-T-3 isopeptidase-T-3, isoform C K12174|1|0.0|795|dsi:Dsim_GD11475|Kip1 ubiquitination-promoting complex protein 2 - - - 8674006 508.00 0.165 0.185 0.165059246270496 Up 0.0510500594373266 CG42591 CG42591 - - - - 37053 541.59 95.75 163.985 0.77621946284357 Up 0.702912429005415 CG5773 CG5773, isoform C - - - - 34717 1042.00 0.045 1.075 4.57826784814715 Up 0.459285431250825 CG15482 CG15482 - - - - 42994 3310.00 39.26 39.155 -0.00386362481233878 Down 0.0454695548804649 Smg6 Smg6 K11124|1|0.0|1751|dme:Dmel_CG6369|EST1-like protein A [EC:3.1.-.-] - GO:0004518//nuclease activity GO:0035194//posttranscriptional gene silencing by RNA 35135 4265.65 3.1 3 -0.0473057147783565 Down 0.0653810593052437 ham hamlet, isoform F K04462|1|8e-64|246|tgu:100230662|ecotropic virus integration site 1 protein - GO:0005488//binding - 40903 948.00 0.86 1.485 0.788054366098668 Up 0.264562145027077 Rtnl2 Rtnl2, isoform C - GO:0043231//intracellular membrane-bounded organelle - - 33688 924.00 18.015 17.655 -0.0291218306671898 Down 0.0906419231277242 mRpS2 mitochondrial ribosomal protein S2 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 246621 791.92 0.105 0.83 2.98272200856816 Up 0.350250957601374 CG30447 CG30447, isoform C - - - - 31338 2721.00 0.03 0.14 2.22239242133645 Up 0.120954959714701 CG2901 CG2901 - GO:0031224//intrinsic to membrane - - 37536 3061.51 32.76 32.59 -0.00750600490244459 Down 0.0594703473781535 Vps35 vacuolar protein sorting 35, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0016192//vesicle-mediated transport;GO:0016192//vesicle-mediated transport 318207 3306.00 0.86 0.565 -0.60608579228691 Down 0.169000132082948 CG32783 CG32783 - - - - 41858 1432.80 13.975 11.325 -0.303337232796955 Down 0.398923523973055 ea easter, isoform B K01362|1|0.0|769|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|3|3e-65|249|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - - - 31499 1360.00 21.14 24.515 0.213689384903002 Up 0.364614978206314 lin-52 lin-52, isoform B - - - - 37979 3608.29 66.495 58.055 -0.195825538345991 Down 0.400508519350152 NKAIN Na,K-ATPase interacting, isoform L - - - - 12798336 2299.00 0.135 3.01 4.47873217459623 Up 0.652720908730683 317922 997.00 0.235 0.48 1.03037364904352 Up 0.166391493858143 CG32219 CG32219 K08042|1|1e-15|84.7|dme:Dmel_CG7978|adenylate cyclase 2 [EC:4.6.1.1] - GO:0005488//binding;GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process 31000 8766.79 18.695 23.255 0.314888468666442 Up 0.45598335754854 elav embryonic lethal abnormal vision, isoform D K13208|1|2e-178|626|dvi:Dvir_GJ14725|ELAV like protein 2/3/4 - - - 38257 4093.93 1.965 2.395 0.285496343477574 Up 0.178113855501255 mu2 mutator 2, isoform C - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - GO:0006281//DNA repair;GO:0006281//DNA repair;GO:0006281//DNA repair 19835607 657.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 39445 1843.68 73.74 76.255 0.0483845209830554 Up 0.151697265882974 Klc kinesin light chain, isoform C K10407|1|0.0|961|dme:Dmel_CG5433|kinesin light chain GO:0005875//microtubule associated complex GO:0003774//motor activity GO:0007017//microtubule-based process 39746 3440.00 2.73 2.655 -0.0401890901156989 Down 0.0603288865407476 DNApol-delta DNA-polymerase-delta K02327|1|0.0|2210|dme:Dmel_CG5949|DNA polymerase delta subunit 1 [EC:2.7.7.7] GO:0015630//microtubule cytoskeleton;GO:0042575 GO:0003676//nucleic acid binding;GO:0034061;GO:0008296//3'-5'-exodeoxyribonuclease activity GO:0033554//cellular response to stress;GO:0006271//DNA strand elongation involved in DNA replication 43398 3184.00 6.67 7.545 0.177834139342098 Up 0.222790912693171 wdn wings down K09228|1|5e-43|176|hsa:162962|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006351//transcription, DNA-dependent 14462582 1154.00 0.205 0.505 1.30065947813371 Up 0.195845991282525 19834947 3724.00 1.415 0.395 -1.84087749465478 Down 0.380663056399419 32402 967.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 CG5334 CG5334 - - GO:0046914//transition metal ion binding - 42018 576.32 43.975 53.875 0.292932386504499 Up 0.489796592259939 npf neuropeptide F, isoform C - - - - 3354990 1471.00 0.245 0.205 -0.257157839497124 Down 0.0637300224541012 CG12061 CG12061, isoform F K13753|1|2e-69|263|gga:415431|solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 39057 1499.00 0.03 0.09 1.58496250072116 Up 0.0883304715361247 CG4483 CG4483 - - GO:0046914//transition metal ion binding - 19834844 450.00 0.485 0.01 -5.59991284218713 Down 0.355831462158235 10178951 765.00 0.21 0.175 -0.263034405833794 Down 0.0589420155857879 CG42658 CG42658 - - - - 318215 931.00 0.255 0.05 -2.35049724708413 Down 0.170849293356228 CG32797 CG32797 - - - - 38872 4006.58 11.445 14.15 0.306084590163558 Up 0.405164443270374 Clk clock, isoform H K02223|1|0.0|1206|dsi:Dsim_GD13034|circadian locomoter output cycles kaput protein [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030534//adult behavior;GO:0006259//DNA metabolic process;GO:0042749//regulation of circadian sleep/wake cycle;GO:0023060;GO:0007562//eclosion;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030534//adult behavior;GO:0006259//DNA metabolic process;GO:0042749//regulation of circadian sleep/wake cycle;GO:0023060;GO:0007562//eclosion;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030534//adult behavior;GO:0006259//DNA metabolic process;GO:0042749//regulation of circadian sleep/wake cycle;GO:0023060;GO:0007562//eclosion 19835164 2790.00 0.1 0.145 0.53605290024021 Up 0.0683529256373002 19835578 553.00 0.08 0.01 -3 Down 0.110718531237617 326154 2603.96 50.09 58.82 0.231784172629162 Up 0.431713115836745 CG31689 CG31689, isoform H K05679|1|4e-118|426|mmu:11307|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 14462742 521.00 10.31 8.225 -0.325956748745505 Down 0.380960243032624 39331 1610.00 6.08 6.685 0.136856236649767 Up 0.17504292695813 CG10907 CG10907 K12737|1|0.0|862|dme:Dmel_CG10907|peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity GO:0000377;GO:0044267//cellular protein metabolic process 35842 1468.35 22.005 20.3 -0.116351644322008 Down 0.238772949412231 CG8735 CG8735, isoform B - - - - 42634 1596.75 19.125 14.13 -0.436698282133437 Down 0.517368907674019 mats mob as tumor suppressor, isoform C K06685|1|3e-127|454|dya:Dyak_GE10299|maintenance of ploidy protein MOB1 (MPS1 binder 1) GO:0043231//intracellular membrane-bounded organelle GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0019899//enzyme binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0012501//programmed cell death 3772542 4198.00 0.145 0.44 1.60145062350973 Up 0.203242636375644 Menl-1 malic enzyme like-1 K00029|1|0.0|1217|dme:Dmel_CG7964|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process 318555 1307.77 1.095 1.625 0.569508848314644 Up 0.226555276713776 CG31010 CG31010, isoform B - - - - 19835200 1405.00 0.115 0.095 -0.275634442613427 Down 0.0530973451327434 32626 1058.00 5.81 5.315 -0.128468471873425 Down 0.158103288865407 CG13014 CG13014 - - - - 44885 4061.27 43.52 31.535 -0.464724623379197 Down 0.586184123629639 mys myospheroid, isoform D K05719|1|0.0|1598|dme:Dmel_CG1560|integrin beta 1 GO:0005924//cell-substrate adherens junction;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0007166//cell surface receptor signaling pathway;GO:0007160//cell-matrix adhesion;GO:0007424//open tracheal system development;GO:0016337//cell-cell adhesion;GO:0006929//substrate-dependent cell migration;GO:0010259//multicellular organismal aging;GO:0019827//stem cell maintenance;GO:0010669//epithelial structure maintenance;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0048805;GO:0048565//digestive tract development;GO:0007606//sensory perception of chemical stimulus 40421 710.00 4.37 1.885 -1.21306875623193 Down 0.511788403117158 CG14566 CG14566, isoform B - - - - 33863 2479.10 127.94 127.775 -0.0018617970379767 Down 0.0462620525690133 stai stathmin, isoform E K04381|1|2e-94|346|dme:Dmel_CG31641|stathmin GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007276//gamete generation;GO:0048731;GO:0023033;GO:0009987//cellular process;GO:0007276//gamete generation;GO:0048731;GO:0023033;GO:0009987//cellular process;GO:0007276//gamete generation;GO:0048731;GO:0023033;GO:0009987//cellular process 42049 2369.53 80.665 84.595 0.068629561551738 Up 0.192444855369172 Irc Immune-regulated catalase, isoform B K00430|1|3e-36|154|cel:F09F3.5|peroxidase [EC:1.11.1.7];K00431|2|2e-35|151|dre:569363|thyroid peroxidase [EC:1.11.1.8];K12550|3|2e-35|151|ecb:100056877|lactoperoxidase [EC:1.11.1.7] - - - 39142 2234.68 16.435 15.02 -0.129886643566039 Down 0.237320036983225 Naa60 N(alpha)-acetyltransferase 60, isoform C - - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 35500 2835.73 15.57 15.53 -0.00371111469173578 Down 0.0434552899220711 CG1344 CG1344, isoform B K08876|1|3e-21|103|dre:793792|SCY1-like - - - 246538 4528.13 21.29 18.475 -0.204601585418781 Down 0.344142121252146 Sema-2b Semaphorin-2b, isoform D K06842|1|2e-93|344|dmo:Dmoj_GI21441|semaphorin 6 GO:0016020//membrane;GO:0016020//membrane GO:0005488//binding;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0004871//signal transducer activity GO:0006935//chemotaxis;GO:0007631//feeding behavior;GO:0008039//synaptic target recognition;GO:0035272//exocrine system development;GO:0006935//chemotaxis;GO:0007631//feeding behavior;GO:0008039//synaptic target recognition;GO:0035272//exocrine system development 39560 652.00 10.515 9.79 -0.103068085128085 Down 0.169330339453177 CG13484 CG13484 - - - - 36948 1779.93 9.135 8.42 -0.117584495561093 Down 0.179533747193237 CG6568 CG6568, isoform B - - - - 40524 3005.91 23.03 21.935 -0.0702797047736148 Down 0.163320565315018 CG12582 CG12582, isoform H K01192|1|0.0|1768|dme:Dmel_CG12582|beta-mannosidase [EC:3.2.1.25] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 3771736 1023.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 His1:CG33861 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 39386 1834.00 119.275 116.235 -0.0372471363113549 Down 0.134361378945978 CG5642 CG5642 - GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding GO:0010467//gene expression 19835112 375.00 0.23 0.39 0.761840262805235 Up 0.12696473385286 36093 587.57 1.705 2.145 0.331205908475373 Up 0.187161537445516 CG42733 CG42733, isoform D - - - - 3772081 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33870 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 32763 1224.00 3.435 2.575 -0.415737666747519 Down 0.274633469819046 CG8142 CG8142 K10755|1|0.0|712|dme:Dmel_CG8142|replication factor C subunit 2/4 GO:0015630//microtubule cytoskeleton;GO:0005657//replication fork GO:0003677//DNA binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0000226//microtubule cytoskeleton organization 31669 2185.00 1.645 2.035 0.306941210531006 Up 0.173623035266147 CBP sarcoplasmic calcium-binding protein, isoform C - - - - 35568 868.51 29.895 28.175 -0.0854886005006309 Down 0.204200237749307 CG9410 CG9410, isoform E - - - - 34049 2249.73 20.36 16.015 -0.346313763301012 Down 0.471437062475234 CG13795 CG13795, isoform C K05042|1|1e-31|138|xla:100126661|solute carrier family 6 (neurotransmitter transporter, glycine) member 9;K05034|2|2e-31|137|tgu:100222137|solute carrier family 6 (neurotransmitter transporter, GABA) member 1;K05038|3|4e-31|136|mdo:100030555|solute carrier family 6 (neurotransmitter transporter, glycine) member 5 GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport 36130 1213.00 10.255 9.755 -0.0721137138708256 Down 0.129045040285299 Mat1 menage a trois 1 ortholog K10842|1|2e-153|541|dme:Dmel_CG7614|CDK-activating kinase assembly factor MAT1 GO:0005667//transcription factor complex GO:0046914//transition metal ion binding GO:0006352//DNA-dependent transcription, initiation 5740693 705.00 3.225 1.5 -1.10433665981474 Down 0.443831726324132 CG34453 CG34453 - - - - 38456 2605.04 459.285 438.53 -0.0667141253384909 Down 0.203737947430987 Ubi-p63E Ubiquitin-63E, isoform D K08770|1|0.0|1477|dme:Dmel_CG11624|ubiquitin C GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton - GO:0006909//phagocytosis;GO:0051276//chromosome organization;GO:0002164//larval development;GO:0022613//ribonucleoprotein complex biogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0006351//transcription, DNA-dependent;GO:0043412//macromolecule modification;GO:0006950//response to stress;GO:0006909//phagocytosis;GO:0051276//chromosome organization;GO:0002164//larval development;GO:0022613//ribonucleoprotein complex biogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0006351//transcription, DNA-dependent;GO:0043412//macromolecule modification;GO:0006950//response to stress;GO:0006909//phagocytosis;GO:0051276//chromosome organization;GO:0002164//larval development;GO:0022613//ribonucleoprotein complex biogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0006351//transcription, DNA-dependent;GO:0043412//macromolecule modification;GO:0006950//response to stress 36110 864.00 11.21 14.43 0.364285021685771 Up 0.444789327697794 trsn translin - - GO:0004519//endonuclease activity;GO:0003677//DNA binding GO:0035194//posttranscriptional gene silencing by RNA 3771790 1009.80 19.355 17.435 -0.150719943515607 Down 0.275128780874389 318193 2232.45 7.92 9.56 0.271510187901139 Up 0.325386342623167 CG32756 CG32756, isoform B - - - - 35746 1106.11 10.375 11.44 0.14097571565674 Up 0.222625809008057 rnh1 ribonuclease H1, isoform B K03469|1|9e-174|609|dme:Dmel_CG8729|ribonuclease HI [EC:3.1.26.4] - GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters - 12798276 468.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 CG43139 CG43139, isoform B - - - - 43253 2175.00 0.94 1.265 0.428404723016673 Up 0.166193369436006 NepYr RYamide receptor, isoform C K04225|1|1e-57|224|spu:578108|tachykinin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 7354399 882.44 64.755 62.76 -0.0451462412145127 Down 0.149286752080306 CG17454 CG17454, isoform B K12839|1|1e-120|432|dme:Dmel_CG17454|survival of motor neuron-related-splicing factor 30 GO:0031224//intrinsic to membrane;GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0000380//alternative mRNA splicing, via spliceosome 42177 5160.70 19.725 20.9 0.083477642067424 Up 0.177189274864615 Ssdp Sequence-specific single-stranded DNA-binding protein, isoform D - - - - 43587 2286.00 1409.11 1089.33 -0.371343169663869 Down 0.590212653546427 Mlc2 myosin light chain 2 K12759|1|3e-27|124|spu:578403|myosin regulatory light chain, invertebrate;K12754|2|5e-27|123|dre:30592|myosin regulatory light chain 7;K12753|3|1e-25|118|mdo:100027358|myosin regulatory light chain 5;K12757|5|6e-25|116|tgu:100217641|myosin regulatory light chain 12 GO:0016460//myosin II complex GO:0046872//metal ion binding;GO:0016887//ATPase activity - 33732 2306.80 28.485 34.41 0.272625485866327 Up 0.446803592656188 CG9121 CG9121, isoform D K10380|1|2e-24|114|ssc:100155697|ankyrin - GO:0005198//structural molecule activity;GO:0005198//structural molecule activity - 41598 707.00 19.175 22.69 0.242830031282042 Up 0.388521991810857 CG17327 CG17327, isoform C K04794|1|6e-68|183|dwi:Dwil_GK22001|peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] - - - 246532 1164.00 0.17 0.405 1.25238716163429 Up 0.170122837141725 CG30289 CG30289 K01362|1|8e-32|137|dpo:Dpse_GA18526| [EC:3.4.21.-];K01312|3|2e-28|126|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K09633|5|1e-26|120|xla:779110|transmembrane protease, serine 2 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35033 897.00 0.22 0.775 1.81669278663694 Up 0.286917183991547 CG15136 CG15136, isoform B - - - - 38629 2700.44 780.445 531.295 -0.554783829574687 Down 0.665764099854709 Msr-110 Msr-110, isoform D - - - - 31859 2072.48 12.865 12.165 -0.0807151367953708 Down 0.153447364945186 CG12119 CG12119, isoform B K11426|1|3e-11|70.9|bfo:BRAFLDRAFT_124463|SET and MYND domain-containing protein;K11848|2|7e-11|69.3|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15] GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity - 19835107 943.00 1.37 0.995 -0.461407462416878 Down 0.184255712587505 34988 2668.00 1.385 2.81 1.02068415417174 Up 0.407773081495179 CG4631 CG4631 - - - - 37181 1621.80 107.965 102.225 -0.0788156336897404 Down 0.214271562541276 Jheh2 juvenile hormone epoxide hydrolase 2, isoform D K10719|1|6e-149|527|dme:Dmel_CG15102|juvenile hormone epoxide hydrolase - - - 35627 2884.00 9.88 8.93 -0.145850866463455 Down 0.217573636243561 pgant3 polypeptide GalNAc transferase 3 K00710|1|0.0|1293|dme:Dmel_CG4445|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation;GO:0030155//regulation of cell adhesion;GO:0009311//oligosaccharide metabolic process 53565 2420.05 22.505 19.82 -0.183288602199063 Down 0.32495707304187 bor belphegor, isoform B K08955|1|3e-11|70.9|cin:100179733|ATP-dependent metalloprotease [EC:3.4.24.-];K12196|2|2e-10|68.6|tca:663681|vacuolar protein-sorting-associated protein 4;K13525|3|2e-09|65.1|isc:IscW_ISCW008933|transitional endoplasmic reticulum ATPase;K03063|5|6e-09|63.2|dre:326884|26S proteasome regulatory subunit T3 - GO:0016462//pyrophosphatase activity;GO:0032559 - 14462719 404.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 36201 3295.34 19.05 18.9 -0.0114047632722495 Down 0.0581825386342623 fbl6 fbl6, isoform C K10272|1|0.0|1238|dme:Dmel_CG13213|F-box and leucine-rich repeat protein 6 - - - 37837 2156.00 21.775 21.65 -0.00830569387213969 Down 0.0563994188350284 Chi chip, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding;GO:0008134//transcription factor binding GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0009880//embryonic pattern specification;GO:0006935//chemotaxis;GO:0007562//eclosion;GO:0006928//cellular component movement;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0009880//embryonic pattern specification;GO:0006935//chemotaxis;GO:0007562//eclosion;GO:0006928//cellular component movement;GO:0010557//positive regulation of macromolecule biosynthetic process 37328 3375.57 16.82 12.095 -0.475766936275219 Down 0.520704002113327 Hil hillarin, isoform B - - - - 40507 1421.64 8.265 9.44 0.191772040069527 Up 0.256406022982433 CG11109 CG11109, isoform B K00599|1|1e-10|67.8|dre:553534| [EC:2.1.1.-] - GO:0003676//nucleic acid binding;GO:0008173//RNA methyltransferase activity;GO:0003676//nucleic acid binding;GO:0008173//RNA methyltransferase activity - 19834794 873.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 31585 1808.00 7.915 6.945 -0.188614656155789 Down 0.236164311187426 CG3918 CG3918 - - - - 35211 1970.03 138.03 157.69 0.192109311437201 Up 0.407145687491745 fon fondue, isoform D - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - GO:0006959//humoral immune response;GO:0009653//anatomical structure morphogenesis;GO:0006959//humoral immune response;GO:0009653//anatomical structure morphogenesis;GO:0006959//humoral immune response;GO:0009653//anatomical structure morphogenesis 36541 2036.00 22.065 24.195 0.132949191900813 Up 0.263274336283186 CG13344 CG13344, isoform C K10640|1|8e-39|162|ecb:100058790|E3 ubiquitin-protein ligase RNF25 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 4379900 887.00 1.675 0.54 -1.63312978318167 Down 0.395324263637564 CG34137 CG34137, isoform B - - - - 19836082 1174.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 - CG44569 - - - - 32581 3284.05 12.635 12.59 -0.0051473812257585 Down 0.0472856954167217 kat80 katanin 80, isoform C K03130|1|4e-25|117|bfo:BRAFLDRAFT_65485|transcription initiation factor TFIID subunit D4 GO:0005813//centrosome;GO:0005813//centrosome GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 32684 1786.00 6.065 7.29 0.265411169206427 Up 0.290945713908334 CG13001 CG13001 - - - - 14462669 794.00 39.825 41.94 0.0746524996839204 Up 0.182373530577202 39694 1680.00 10.935 9.635 -0.182596648752372 Down 0.26297714964998 CG7650 CG7650 K08327|1|6e-35|149|mdo:100024764|phosducin - - - 40611 1021.56 241.2 187.595 -0.362608531257494 Down 0.576641130630036 CG14661 CG14661, isoform B - - - - 42221 3265.73 17.64 19.145 0.11811709929264 Up 0.230947034737815 CG31122 CG31122, isoform C - - - - 3772455 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 35115 1658.00 0.12 0.055 -1.12553088208386 Down 0.0856557918372738 Cyp310a1 Cyp310a1 K00517|1|0.0|957|dme:Dmel_CG10391| [EC:1.14.-.-];K07424|5|8e-39|161|tca:659054|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0016055//Wnt receptor signaling pathway;GO:0008152//metabolic process 42023 1688.00 0.05 0.03 -0.736965594166206 Down 0.0552767137762515 CG14893 CG14893 K13356|1|1e-94|347|api:100166286|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 35433 2031.00 0.115 0.105 -0.131244533278252 Down 0.0444459120327566 CG1428 CG1428 - - - - 37672 1209.00 0.225 0.53 1.23606735823352 Up 0.197001717078325 CG3215 CG3215 K00006|1|0.0|729|dme:Dmel_CG3215|glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] GO:0043234//protein complex;GO:0044424//intracellular part GO:0042802//identical protein binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0000166//nucleotide binding GO:0006072//glycerol-3-phosphate metabolic process 34148 4553.80 10.145 13.865 0.45067875128282 Up 0.487650244353454 CG7627 CG7627, isoform B K05673|1|0.0|1671|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|2|0.0|1392|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 4379866 974.00 1.43 1.685 0.236733444403469 Up 0.12650244353454 CG34130 CG34130 K01312|1|7e-09|61.2|dme:Dmel_CG12385|trypsin [EC:3.4.21.4];K09640|2|7e-09|61.2|rno:314636|transmembrane protease, serine 9 [EC:3.4.21.-];K01333|3|5e-08|58.5|xla:379108|complement factor I [EC:3.4.21.45] - - - 43155 957.00 3 3.66 0.286881147788162 Up 0.222262580900806 E(spl)m2-BFM enhancer of split m2, bearded family member - - - - 5740219 198.00 0.255 0.29 0.185555653156076 Up 0.0565645225201427 CG34211 CG34211 - - - - 35326 2244.42 6.455 5.84 -0.144448726427174 Down 0.177882710342095 CG2614 CG2614, isoform C K01415|1|1e-23|112|mdo:100025935|endothelin-converting enzyme [EC:3.4.24.71] - GO:0016741 - 19835346 797.00 0.25 0.01 -4.64385618977472 Down 0.24085325584467 3885654 6084.11 15.495 19.67 0.344194202692314 Up 0.464337604015322 CG33981 CG33981, isoform C K00921|1|0.0|3282|dme:Dmel_CG6355|1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150] GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0046914//transition metal ion binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0032559 GO:0007041//lysosomal transport;GO:0023033;GO:0030384;GO:0019538//protein metabolic process;GO:0007041//lysosomal transport;GO:0023033;GO:0030384;GO:0019538//protein metabolic process 36440 4387.00 4.26 4.56 0.0981803939389033 Up 0.114350812310131 Cap-G Cap-G, isoform G K06678|1|0.0|2302|dme:Dmel_CG34438|condensin complex subunit 3 GO:0000793//condensed chromosome;GO:0000793//condensed chromosome - GO:0070193//synaptonemal complex organization;GO:0000070//mitotic sister chromatid segregation;GO:0051301//cell division;GO:0070193//synaptonemal complex organization;GO:0000070//mitotic sister chromatid segregation;GO:0051301//cell division 40501 1103.00 1.16 0.9 -0.366127898797898 Down 0.144762911108176 CG11226 CG11226 - - - - 36104 4580.42 109.85 128.965 0.231444713889853 Up 0.451591599524501 G-oalpha47A G protein alpha o subunit, isoform J K04534|1|0.0|713|dya:Dyak_GE19363|guanine nucleotide binding protein (G protein), alpha o polypeptide GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity 36639 2301.95 7.93 8.95 0.17456681644764 Up 0.233324527803461 CG10151 CG10151, isoform D - - - - 12797876 608.25 31.805 40.695 0.355597961819771 Up 0.529916787742702 CG43402 CG43402, isoform B - - - - 36991 340.44 387.54 387.615 0.000279175464015392 Up 0.0449742438251222 CG14482 CG14482, isoform B K00420|1|3e-19|92.8|dya:Dyak_GE13985|ubiquinol-cytochrome c reductase subunit 10 [EC:1.10.2.2] - - - 5740644 436.00 0.39 0.135 -1.53051471669878 Down 0.179863954563466 CG34288 CG34288 - - - - 19835664 653.00 0.445 0.515 0.210767096216821 Up 0.0727446836613393 246507 739.00 36.76 31.775 -0.210244641396713 Down 0.388621054021926 CG30185 CG30185 K03233|1|5e-08|57.8|api:100164654|elongation factor EF-1 gamma subunit GO:0044424//intracellular part GO:0005488//binding GO:0048522//positive regulation of cellular process 41426 1718.86 19.67 20.915 0.0885410403655047 Up 0.190661735569938 HisCl1 Histamine-gated chloride channel subunit 1, isoform D K05195|1|3e-64|246|mdo:100018475|glycine receptor alpha-3;K05194|2|6e-64|245|dre:83413|glycine receptor alpha-2 GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0015276//ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0015276//ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0015276//ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0015276//ligand-gated ion channel activity;GO:0005254//chloride channel activity GO:0006810//transport;GO:0009266//response to temperature stimulus;GO:0006810//transport;GO:0009266//response to temperature stimulus;GO:0006810//transport;GO:0009266//response to temperature stimulus;GO:0006810//transport;GO:0009266//response to temperature stimulus 3346177 1073.00 16.85 14.93 -0.174534425934679 Down 0.290714568749175 CG33506 CG33506 - - - - 36331 2243.53 0.225 0.53 1.23606735823352 Up 0.197001717078325 CG8850 CG8850, isoform B K05336|1|0.0|1167|dme:Dmel_CG8850|solute carrier family 6 (neurotransmitter transporter), invertebrate GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport;GO:0006810//transport 42524 1804.00 191.48 170.8 -0.164885736211914 Down 0.365341434420816 Rab1 Rab1 K07874|1|2e-114|412|dya:Dyak_GE25003|Ras-related protein Rab-1A GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032561//guanyl ribonucleotide binding;GO:0005515//protein binding;GO:0032559 GO:0006351//transcription, DNA-dependent;GO:0065008;GO:0015031//protein transport;GO:0030036//actin cytoskeleton organization;GO:0048193//Golgi vesicle transport;GO:0031345//negative regulation of cell projection organization;GO:0035556//intracellular signal transduction 19835799 771.00 0.105 0.175 0.736965594166206 Up 0.0868115176330736 19835477 612.00 0.46 0.32 -0.523561956057013 Down 0.112468630299828 35362 2930.00 22.105 22.345 0.0155793104409439 Up 0.0722823933430194 Mtp microsomal triacylglycerol transfer protein - - GO:0022892 GO:0006810//transport 10178861 1824.00 4.73 5.725 0.275435509644911 Up 0.266708492933562 pre-mod(mdg4)-T pre-mod(mdg4)-T - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 19834759 646.00 0.01 0.705 6.13955135239879 Up 0.42887333245278 - CG45487 - - - - 19835818 716.00 13.57 5.825 -1.22009076587721 Down 0.656254127592128 10178939 2562.28 0.065 0.175 1.42884329880387 Up 0.115473517368908 CG42660 CG42660, isoform B - GO:0031224//intrinsic to membrane - - 32425 2608.02 34.565 35.715 0.0472181956843106 Up 0.139974904239863 Flo-2 flotillin 2, isoform L K07192|1|2e-162|546|dme:Dmel_CG32593|flotillin GO:0005901//caveola;GO:0005901//caveola;GO:0005901//caveola;GO:0005901//caveola;GO:0005901//caveola;GO:0005901//caveola;GO:0005901//caveola;GO:0005901//caveola - GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process 33963 1081.00 3.75 3.59 -0.062906751560192 Down 0.0790186236956809 CG13773 CG13773 K03004|1|8e-125|446|dme:Dmel_CG13773|DNA-directed RNA polymerase I subunit A43 [EC:2.7.7.6] - GO:0034062//RNA polymerase activity - 33999 1921.89 38.96 39.995 0.0378259744276399 Up 0.123662660150575 CG4495 CG4495, isoform B - - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 36078 1253.00 0.255 0.445 0.803308088994902 Up 0.139545634658566 CG12914 CG12914, isoform C - - - - 19835421 432.00 0.11 0.22 1 Up 0.112336547351737 41934 442.00 0.15 0.11 -0.447458976971221 Down 0.067956676793026 CG34276 CG34276, isoform B K06238|1|4e-07|53.1|mdo:100017951|collagen, type VI, alpha;K03909|3|3e-06|50.1|mmu:21788|tissue factor pathway inhibitor - - - 37152 5811.84 13.41 13.57 0.0171114835143802 Up 0.0657773081495179 Sik3 Salt-inducible kinase 3, isoform F K08282|1|9e-104|379|dre:393513|non-specific serine/threonine protein kinase [EC:2.7.11.1];K08286|2|2e-93|345|dme:Dmel_CG4290|protein-serine/threonine kinase [EC:2.7.11.-] GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 39240 3714.00 5.125 5.49 0.0992541446123903 Up 0.126469422797517 CG7839 CG7839 - GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity - 50285 509.50 1.01 1.44 0.511713518690518 Up 0.199280147932902 CG8750 CG8750, isoform B - - - - 34886 5367.95 16.07 21.065 0.39047798688716 Up 0.500858539162594 CG15270 CG15270, isoform F K13982|1|0.0|1236|dgr:Dgri_GH10918|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13] - GO:0017111//nucleoside-triphosphatase activity;GO:0000166//nucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0000166//nucleotide binding - 36586 2673.67 68.78 63.86 -0.107076562956697 Down 0.265486725663717 CG8547 CG8547, isoform E - - - - 39820 1595.16 79.54 71.215 -0.15949941440097 Down 0.350911372341831 CG4729 CG4729, isoform E K13523|1|1e-79|295|dme:Dmel_CG4729|lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 117419 2149.00 3.38 3.77 0.15754127698648 Up 0.148098005547484 Irbp inverted repeat-binding protein, isoform B K10884|1|0.0|1271|dme:Dmel_CG5247|ATP-dependent DNA helicase 2 subunit 1 GO:0043234//protein complex;GO:0044428//nuclear part GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0004674//protein serine/threonine kinase activity GO:0000726 10178871 525.08 12.985 15.93 0.294900252846902 Up 0.404603090740985 36635 355.00 94.305 54.48 -0.791607560487544 Down 0.69554880464932 Dro drosocin, isoform B - - GO:0051635//bacterial cell surface binding GO:0002812 38239 856.00 2.26 2.56 0.179821037584813 Up 0.132479196935676 Cpr62Ba cuticular protein 62Ba, isoform C - - GO:0005198//structural molecule activity;GO:0005198//structural molecule activity - 37179 1077.00 0.145 0.17 0.229481846122767 Up 0.0521727644961036 CG18190 CG18190 K10436|1|3e-45|182|isc:IscW_ISCW006702|microtubule-associated protein, RP/EB family - - - 19835003 1042.00 0.195 0.13 -0.584962500721156 Down 0.0797781006472064 40582 2092.76 18.93 20.81 0.13660255403163 Up 0.265123497556465 CG12001 spartin, isoform B K10799|1|4e-66|253|cqu:CpipJ_CPIJ017909|tankyrase [EC:2.4.2.30] - - - 33818 1201.00 0.04 0.01 -2 Down 0.0694426099590543 CG9021 CG9021, isoform B - - - - 3771966 1251.00 8.435 9.055 0.102326572662602 Up 0.158631620657773 CG9960 CG9960 K00571|1|2e-31|136|hsa:29104|site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] - GO:0005488//binding;GO:0016741 GO:0016079//synaptic vesicle exocytosis;GO:0006730//one-carbon metabolic process 31103 1564.00 16.29 16.98 0.0598498550275208 Up 0.137003037907806 Rab27 Rab27, isoform C K07976|1|9e-129|460|dya:Dyak_GE16524|Rab family, other - - - 37135 1166.00 2.175 2.34 0.105493128847314 Up 0.0901796328094043 CG10927 CG10927 - - - - 39369 1770.00 0.65 0.1 -2.70043971814109 Down 0.302205785233126 CG6793 CG6793 K11515|1|2e-16|87.8|cin:100186162|inner centromere protein;K05702|4|5e-16|86.3|hmg:100201659|afadin - - - 12797911 430.00 0.2 0.135 -0.567040592723894 Down 0.0792497688548408 CG43083 CG43083 - - - - 34975 1528.00 13.555 7.155 -0.921801441111044 Down 0.617454761590279 CG4455 CG4455 - - - - 36044 1239.00 9.1 10.885 0.258402957102148 Up 0.331924448553692 CG12129 CG12129 - GO:0044424//intracellular part GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0044260 39977 4777.00 0.15 0.195 0.37851162325373 Up 0.0672302205785233 CG42816 CG42816 K05643|1|2e-157|557|gga:416386|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 31336 3007.00 0.36 0.38 0.0780025120012732 Up 0.0463611147800819 fd3F forkhead domain 3F - - - - 41549 6378.36 7.05 8.2 0.21800065221929 Up 0.265949015982037 Octbeta2R octopamine beta2 receptor, isoform F K04142|1|1e-56|221|mcc:710146|adrenergic receptor beta-2;K04141|5|3e-54|213|dre:557194|adrenergic receptor beta-1 GO:0031224//intrinsic to membrane GO:0008227//G-protein coupled amine receptor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0007166//cell surface receptor signaling pathway;GO:0023060 2768908 2341.00 7.45 14.405 0.951257329810347 Up 0.626997754589882 CG3857 CG3857 - - - - 14462848 527.00 0.41 1.145 1.48165178347886 Up 0.319772817329283 32199 2625.00 0.135 0.18 0.415037499278844 Up 0.0678576145819575 Lsp1alpha larval serum protein 1 alpha K00505|1|2e-38|161|dme:Dmel_CG42639|tyrosinase [EC:1.14.18.1] GO:0044444//cytoplasmic part GO:0022892 GO:0051234//establishment of localization 14462407 371.00 0.38 0.285 -0.415037499278844 Down 0.0914674415532955 43085 2005.00 0.415 0.525 0.339206086319198 Up 0.0962224276845859 CG5111 CG5111 - - - - 36805 943.00 0.455 0.555 0.28662122615141 Up 0.0890569277506274 CG15708 CG15708 - - GO:0003676//nucleic acid binding - 41893 846.00 52.375 44.895 -0.222323559254819 Down 0.416259410910052 CG44014 CG44014 - - - - 19835494 899.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 38986 2121.00 18.43 26.335 0.514925388523244 Up 0.575485404834236 S-Lap1 Sperm-Leucylaminopeptidase 1 K01255|1|0.0|1083|dme:Dmel_CG6372|leucyl aminopeptidase [EC:3.4.11.1];K11142|2|0.0|1002|dpo:Dpse_GA19547|cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process;GO:0007420//brain development 34551 4883.00 8.585 8.355 -0.0391783059409463 Down 0.084070796460177 CG4751 CG4751 K11865|1|3e-16|88.6|nve:NEMVE_v1g31202|protein MYSM1 - - - 41381 1794.18 15 16.59 0.14535138557262 Up 0.260863822480518 dpr5 dpr5, isoform B K06491|1|7e-10|65.5|xtr:100151722|neural cell adhesion molecule;K06774|2|3e-07|56.6|mdo:100017555|neurotrimin - - - 10178805 463.06 0.27 0.01 -4.75488750216347 Down 0.252509576013737 CG42654 CG42654, isoform C - - - - 39157 1529.00 2.455 2.855 0.21776772104815 Up 0.159787346453573 Cdk8 Cyclin-dependent kinase 8 K02208|1|0.0|794|dme:Dmel_CG10572|cyclin-dependent kinase 8/11 [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0022402//cell cycle process;GO:0010468//regulation of gene expression;GO:0006464//cellular protein modification process 42026 2605.11 7.38 11 0.575810802351626 Up 0.510599656584335 nonA-l nonA-like, isoform B K13219|1|3e-180|632|dya:Dyak_GE24585|splicing factor, proline- and glutamine-rich - - - 39119 2926.00 4.52 4.71 0.0594042871975955 Up 0.0850614185708625 CG3335 CG3335 K11294|1|7e-10|66.6|tgu:100232634|nucleolin;K12838|5|5e-09|63.9|smm:Smp_012900|poly(U)-binding-splicing factor PUF60 - GO:0003723//RNA binding - 5740555 502.64 19.99 18.53 -0.109415590717362 Down 0.219587901201955 CG34293 CG34293, isoform B - - - - 40849 2396.06 198.68 164.84 -0.269380283156739 Down 0.49907541936336 Mlp84B muscle LIM protein at 84B, isoform B K09377|1|6e-47|189|bfo:BRAFLDRAFT_269843|cysteine and glycine-rich protein GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity GO:0031032//actomyosin structure organization;GO:0048869//cellular developmental process;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0048869//cellular developmental process;GO:0014706//striated muscle tissue development 31385 888.00 7.09 9.1 0.360080917846543 Up 0.38426231673491 CG15912 CG15912 - - GO:0016791//phosphatase activity - 49895 4310.00 0.945 0.145 -2.7042614290935 Down 0.361874257033417 CG17018 CG17018, isoform F - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 33589 341.48 121.79 71.415 -0.770096645784832 Down 0.697166820763439 CG16704 CG16704, isoform B - - GO:0004866//endopeptidase inhibitor activity - 38486 1072.00 2.93 2.885 -0.0223293457767656 Down 0.0513472460705323 CG14990 CG14990 K09640|1|1e-28|127|xtr:448231|transmembrane protease, serine 9 [EC:3.4.21.-];K09634|3|7e-27|121|tgu:100220345|transmembrane protease, serine 3 [EC:3.4.21.-];K01312|4|3e-26|119|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01310|5|5e-26|118|mdo:100023625|chymotrypsin [EC:3.4.21.1] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39237 690.00 4.43 5.665 0.354769257265498 Up 0.315116893409061 CG6310 CG6310 - - - - 40313 1365.00 1.975 2.285 0.210341511993604 Up 0.138885219918109 CG10589 CG10589 - - - - 37545 2982.74 20.02 20.455 0.0310115630520526 Up 0.0940760797781006 Oatp58Dc organic anion transporting polypeptide 58Dc, isoform C - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 19835454 1719.36 0.68 0.84 0.304854581528421 Up 0.110223220182274 34603 1155.00 0.04 0.01 -2 Down 0.0694426099590543 Or33c odorant receptor 33c K08471|1|0.0|759|dme:Dmel_CG5006|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0007166//cell surface receptor signaling pathway;GO:0023060 31152 937.00 1.815 1.52 -0.255898224552165 Down 0.139611676132611 CG32801 CG32801 - - - - 45031 1977.88 22.445 19.07 -0.235089252602789 Down 0.385318980319641 Pp4-19C protein phosphatase 19C, isoform H K01090|1|0.0|641|dme:Dmel_CG32505|protein phosphatase [EC:3.1.3.16] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0000278//mitotic cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0006464//cellular protein modification process;GO:0000278//mitotic cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0006464//cellular protein modification process 40942 568.52 0.01 1.845 7.5274770060604 Up 0.643739268260468 Os-C Os-C, isoform D - - - - 40875 2899.00 11.115 7.275 -0.611488795231344 Down 0.521991810857218 Gld glucose dehydrogenase K00108|1|0.0|1216|dme:Dmel_CG1152|choline dehydrogenase [EC:1.1.99.1];K00115|2|0.0|1132|dpo:Dpse_GA11047|glucose dehydrogenase (acceptor) [EC:1.1.99.10] - GO:0030554//adenyl nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors GO:0035209//pupal development;GO:0046692//sperm competition;GO:0019318//hexose metabolic process 42006 6918.00 0.19 0.155 -0.29373120305671 Down 0.0645885616166953 Cad89D cadherin 89D K06813|1|1e-56|223|ecb:100146534|cadherin 23 - - - 40936 1053.35 66.145 53.11 -0.316648575707586 Down 0.523246598864087 CG2846 CG2846, isoform B K00861|1|1e-83|310|dme:Dmel_CG2846|riboflavin kinase [EC:2.7.1.26] GO:0044424//intracellular part GO:0016301//kinase activity GO:0006771//riboflavin metabolic process 43755 1125.77 4.225 3.42 -0.304955016283649 Down 0.247094175141989 CG1971 CG1971, isoform D - - - - 38889 846.00 5.89 7.05 0.259355623455695 Up 0.279619601109497 CG8038 CG8038 K03538|1|4e-117|420|dme:Dmel_CG8038|ribonuclease P subunit P29 [EC:3.1.26.5] GO:0030681;GO:0005732//small nucleolar ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0004518//nuclease activity GO:0006399//tRNA metabolic process;GO:0042254//ribosome biogenesis;GO:0006397//mRNA processing 41042 1519.00 18.015 13.815 -0.382963089614299 Down 0.480286619997358 CG9797 motif 1 binding protein K09228|1|2e-32|140|mmu:434377|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19835403 2479.00 0.085 0.065 -0.387023123109247 Down 0.0544181746136574 34141 2520.57 0.705 1.535 1.12254349297139 Up 0.322150310394928 mtsh mitoshell, isoform D - - - - 19835656 722.00 0.68 1.26 0.889817082249577 Up 0.259741117421741 12798367 505.00 0.41 0.64 0.642447995381916 Up 0.146248844274204 CG43292 CG43292 - - - - 34981 1692.92 72.91 67.975 -0.101112455284298 Down 0.248745211993132 Idgf3 imaginal disc growth factor 3, isoform D K01183|1|7e-38|158|ecb:100065255|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0070851//growth factor receptor binding;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0070851//growth factor receptor binding;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0070851//growth factor receptor binding;GO:0043167//ion binding GO:0048513//organ development;GO:0006026;GO:0048513//organ development;GO:0006026;GO:0048513//organ development;GO:0006026 33216 665.00 0.19 0.215 0.178337241258513 Up 0.0562343151499141 CG13692 CG13692 K07942|1|3e-06|51.2|cel:F54C9.10|ADP-ribosylation factor-like 1;K07944|2|3e-06|51.2|tca:655152|ADP-ribosylation factor-like 3 - GO:0032561//guanyl ribonucleotide binding;GO:0005083//small GTPase regulator activity - 34553 3760.00 0.835 1.025 0.295775807031394 Up 0.119369964337604 Gyc32E guanyl cyclase at 32E, isoform G K01769|1|0.0|2315|dme:Dmel_CG33114|guanylate cyclase, other [EC:4.6.1.2] GO:0016020//membrane;GO:0016020//membrane GO:0016829//lyase activity;GO:0004871//signal transducer activity;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0032559;GO:0016829//lyase activity;GO:0004871//signal transducer activity;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0032559 GO:0023060;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023060;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0006464//cellular protein modification process 31651 1167.00 0.01 0.08 3 Up 0.110718531237617 CG14427 CG14427 - - - - 31466 1269.09 29.24 29.26 0.00098645818604938 Up 0.0416061286487914 CG12730 CG12730, isoform B - GO:0044464//cell part - - 35297 628.00 30.455 29.205 -0.060463719642225 Down 0.156848500858539 Taf13 TBP-associated factor 13 K03127|1|3e-58|224|dya:Dyak_GE12606|transcription initiation factor TFIID subunit D11 GO:0005667//transcription factor complex GO:0008135//translation factor activity, nucleic acid binding;GO:0030528//transcription regulator activity GO:0006352//DNA-dependent transcription, initiation 37072 3014.05 9.855 9.77 -0.0124973090751006 Down 0.053625676925109 CG5742 CG5742, isoform C K10683|1|8e-06|53.1|tgu:100229796|BRCA1-associated RING domain protein 1 [EC:6.3.2.19] - - - 19835173 353.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 38518 2631.00 4.925 5.015 0.0261259762684423 Up 0.0602958658037247 CG15011 CG15011 K12236|1|2e-99|363|dan:Dana_GF14341|transcriptional repressor NF-X1 [EC:6.3.2.-] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent 40459 2604.17 160.75 166.8 0.0533005512293542 Up 0.15744287412495 Csp cysteine string protein, isoform F K09525|1|1e-97|357|der:Dere_GG16248|DnaJ homolog subfamily C member 5 GO:0005626//insoluble fraction;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0005626//insoluble fraction;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0005626//insoluble fraction;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006887//exocytosis;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0001505//regulation of neurotransmitter levels;GO:0048488//synaptic vesicle endocytosis;GO:0009605//response to external stimulus;GO:0044267//cellular protein metabolic process;GO:0006887//exocytosis;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0001505//regulation of neurotransmitter levels;GO:0048488//synaptic vesicle endocytosis;GO:0009605//response to external stimulus;GO:0044267//cellular protein metabolic process;GO:0006887//exocytosis;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0001505//regulation of neurotransmitter levels;GO:0048488//synaptic vesicle endocytosis;GO:0009605//response to external stimulus 33026 1589.24 28.935 36.62 0.339816147027077 Up 0.511227050587769 CG17065 CG17065, isoform D K01443|1|0.0|872|dme:Dmel_CG17065|N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0006041//glucosamine metabolic process;GO:0006041//glucosamine metabolic process 318988 764.00 0.625 0.98 0.648925559453121 Up 0.188317263241316 CG31861 CG31861 - - - - 35082 563.00 0.73 0.405 -0.849974555995393 Down 0.186963413023379 CG15152 CG15152, isoform B - - - - 39293 2904.48 100.75 159.465 0.662459971648366 Up 0.679302602034077 Mob2 Mob2, isoform E K06685|1|2e-34|148|spu:583788|maintenance of ploidy protein MOB1 (MPS1 binder 1) GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0042051//compound eye photoreceptor development;GO:0005975//carbohydrate metabolic process;GO:0032989;GO:0007610//behavior;GO:0042051//compound eye photoreceptor development;GO:0005975//carbohydrate metabolic process;GO:0032989;GO:0007610//behavior;GO:0042051//compound eye photoreceptor development;GO:0005975//carbohydrate metabolic process;GO:0032989;GO:0007610//behavior;GO:0042051//compound eye photoreceptor development;GO:0005975//carbohydrate metabolic process;GO:0032989;GO:0007610//behavior 32881 1695.00 5.505 6.17 0.164527925585049 Up 0.189836217144367 CG7288 CG7288 K12847|1|0.0|1021|dme:Dmel_CG7288|U4/U6.U5 tri-snRNP-associated protein 2 GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity GO:0000377;GO:0019941//modification-dependent protein catabolic process 31420 2571.80 23.2 21.315 -0.122255750050998 Down 0.244749702813367 CG32772 CG32772, isoform F K09228|1|4e-53|210|bta:532421|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 40629 1797.00 1.725 2.65 0.61939599778503 Up 0.304748381983886 CG1113 CG1113, isoform B - - - - 42897 3490.00 15.235 18.09 0.247802907934755 Up 0.377625148593317 Nab2 Nab2 K04573|1|7e-07|57.0|tgu:751981|neurofilament medium polypeptide (neurofilament 3) - GO:0046914//transition metal ion binding GO:0006909//phagocytosis 42912 1484.00 0.105 0.09 -0.222392421336448 Down 0.0521727644961036 CG17782 CG17782 - - - - 43028 3736.01 9.985 9.87 -0.0167123429875747 Down 0.0598335754854048 CG13654 CG13654, isoform C - GO:0031224//intrinsic to membrane - GO:0006810//transport 5740691 2871.50 3.365 3.78 0.167779729610756 Up 0.155098401796328 l(2)41Ab lethal (2) 41Ab, isoform B K04371|1|4e-130|466|der:Dere_GG23119|extracellular signal-regulated kinase 1/2 [EC:2.7.11.24];K10352|2|2e-20|101|gga:395350|myosin heavy chain - GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 32319 1463.31 5.745 5.195 -0.145183143741901 Down 0.171443666622639 Tango2 transport and golgi organization 2, isoform D K08282|1|2e-12|73.9|spu:575551|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0044444//cytoplasmic part - GO:0006996//organelle organization 34223 1246.00 0.155 0.29 0.903784684740697 Up 0.117454761590279 CG9555 CG9555, isoform C - - - - 31738 4521.00 29.85 30.56 0.0339136118835813 Up 0.102364284770836 Smox smad on X, isoform B K04500|1|0.0|854|dya:Dyak_GE17479|SMAD, mothers against DPP 2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0000278//mitotic cell cycle;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 47762 1508.96 55.165 65.525 0.248292223966302 Up 0.455587108704266 FKBP59 FK506-binding protein FKBP59, isoform B K09571|1|0.0|857|dme:Dmel_CG4535|FK506-binding protein 4/5 [EC:5.2.1.8] GO:0016028//rhabdomere GO:0016859//cis-trans isomerase activity;GO:0005527//macrolide binding GO:0044267//cellular protein metabolic process;GO:0009584//detection of visible light;GO:0007399//nervous system development;GO:0010959//regulation of metal ion transport 32822 2397.21 110.165 90.195 -0.288546580532781 Down 0.509972262580901 CG32549 CG32549, isoform H K01081|1|0.0|1137|dme:Dmel_CG32549|5'-nucleotidase [EC:3.1.3.5] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding - 37441 1033.00 13.12 5.72 -1.19768066783969 Down 0.65083872672038 CG17974 CG17974 - - - - 42492 1253.67 285.675 207.185 -0.463455231587169 Down 0.629738475762779 AnnIX annexin B9, isoform F - - GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007450//dorsal/ventral pattern formation, imaginal disc 34320 2806.43 60.795 87.71 0.528788660611468 Up 0.636342623167349 CG31712 CG31712, isoform B K13173|1|1e-57|224|dya:Dyak_GE10160|arginine and glutamate-rich protein 1 - - - 37839 884.38 16.805 18.335 0.125709723403664 Up 0.242306168273676 CG13567 Not11, isoform C - - - - 32876 2256.06 9.45 6.035 -0.646960558353413 Down 0.511127988376701 Pvf1 PDGF- and VEGF-related factor 1, isoform C K05448|1|4e-11|70.1|rno:83785|vascular endothelial growth factor A/B, PGF;K04359|2|1e-10|68.6|xtr:100038202|platelet derived growth factor A/B;K05449|4|1e-10|68.2|hsa:7424|vascular endothelial growth factor C/D GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005126//cytokine receptor binding;GO:0005539//glycosaminoglycan binding;GO:0005126//cytokine receptor binding;GO:0005539//glycosaminoglycan binding GO:0030030//cell projection organization;GO:0007297//ovarian follicle cell migration;GO:0048598//embryonic morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048522//positive regulation of cellular process;GO:0007431//salivary gland development;GO:0030030//cell projection organization;GO:0007297//ovarian follicle cell migration;GO:0048598//embryonic morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048522//positive regulation of cellular process;GO:0007431//salivary gland development 42767 5240.00 2.73 1.295 -1.0759488532333 Down 0.41137234183067 CG4374 CG4374, isoform C K10519|1|8e-12|73.6|mcc:704628|zinc finger and BTB domain-containing protein 48 - - - 2769007 440.00 2.395 2.3 -0.0583917947918052 Down 0.0667679302602034 Rdh Rdh - - - - 34306 393.00 5.39 5.555 0.0435016386365864 Up 0.0758816536785101 CG4537 CG4537 - - - - 43310 5462.77 19.255 20.42 0.0847497430808158 Up 0.176859067494386 Klp98A Kinesin-like protein at 98A, isoform B K10392|1|0.0|1310|aga:AgaP_AGAP003925|kinesin family member 1/13/14 GO:0015630//microtubule cytoskeleton GO:0005543//phospholipid binding;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 50300 589.70 384.7 262.705 -0.550290170439885 Down 0.663452648263109 CG13315 CG13315, isoform B - - - - 39994 1894.00 4.205 7.115 0.758757956271338 Up 0.502971866332056 CG7402 CG7402 K01135|1|0.0|1147|dme:Dmel_CG7402|arylsulfatase B [EC:3.1.6.12] - GO:0016788//hydrolase activity, acting on ester bonds - 32888 1589.44 92.265 102.775 0.155633990126533 Up 0.35622771100251 CG7378 CG7378, isoform C K04459|1|8e-35|147|spu:587147|dual specificity phosphatase [EC:3.1.3.16 3.1.3.48];K01090|2|8e-32|137|dre:664697|protein phosphatase [EC:3.1.3.16];K01104|3|1e-31|137|mcc:704480|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 32579 3102.44 4.425 5.15 0.218894977100221 Up 0.215097080966847 disco disconnected, isoform B - GO:0044464//cell part;GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0007417//central nervous system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007562//eclosion;GO:0007626//locomotory behavior;GO:0007417//central nervous system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007562//eclosion;GO:0007626//locomotory behavior 31647 1496.52 18.085 17.665 -0.0338998487651219 Down 0.0937458724078721 cm carmine, isoform B K12398|1|0.0|837|dme:Dmel_CG3035|AP-3 complex subunit mu - - - 32729 7805.85 9.64 9.48 -0.0241460873317026 Down 0.0657773081495179 CG43658 CG43658, isoform H K04436|1|3e-21|105|mmu:30957|mitogen-activated protein kinase 8 interacting protein 3 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 33438 1600.45 17.955 45.88 1.35347973835117 Up 0.733687755910712 Cyp309a1 Cyp309a1, isoform C K00517|1|3e-146|518|dme:Dmel_CG18559| [EC:1.14.-.-] - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 31429 6240.86 3.085 2.525 -0.288987101510261 Down 0.204794611015718 ovo ovo, isoform E K09216|1|5e-128|459|dme:Dmel_CG6824|ovo GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding GO:0007542;GO:0003002//regionalization;GO:0048066//developmental pigmentation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030030//cell projection organization;GO:0019748//secondary metabolic process;GO:0008544//epidermis development;GO:0007631//feeding behavior;GO:0007542;GO:0003002//regionalization;GO:0048066//developmental pigmentation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030030//cell projection organization;GO:0019748//secondary metabolic process;GO:0008544//epidermis development;GO:0007631//feeding behavior;GO:0007542;GO:0003002//regionalization;GO:0048066//developmental pigmentation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030030//cell projection organization;GO:0019748//secondary metabolic process;GO:0008544//epidermis development;GO:0007631//feeding behavior;GO:0007542;GO:0003002//regionalization;GO:0048066//developmental pigmentation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030030//cell projection organization;GO:0019748//secondary metabolic process;GO:0008544//epidermis development;GO:0007631//feeding behavior 19835363 814.00 0.1 0.885 3.14567745519564 Up 0.367520803064324 40372 1785.00 0.045 0.1 1.15200309344505 Up 0.0858869369964338 CG5656 CG5656, isoform B K01077|1|0.0|1048|dme:Dmel_CG5656|alkaline phosphatase [EC:3.1.3.1] - GO:0042578//phosphoric ester hydrolase activity - 42127 3638.02 33.605 30.8 -0.125745552873763 Down 0.27849689605072 alt aluminum tubes, isoform I K14000|1|7e-12|73.6|nvi:100123647|ribosome-binding protein 1 - - - 251324 563.00 1.13 0.965 -0.227721925147107 Down 0.102001056663585 CG30270 CG30270, isoform D - - - - 38198 1242.00 41.27 47.1 0.190633621493111 Up 0.37627129837538 Bgb Big brother, isoform B - GO:0005667//transcription factor complex GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity GO:0006357//regulation of transcription from RNA polymerase II promoter 14462469 1271.00 0.09 0.175 0.959358015502654 Up 0.0946374323074891 40698 2798.00 9.525 9.43 -0.0144613217055879 Down 0.0547483819838859 CG1109 CG1109, isoform B K03130|1|3e-23|110|mmu:102162|transcription initiation factor TFIID subunit D4 - - - 44353 3176.00 5.07 4.18 -0.278482804922458 Down 0.253731343283582 shark SH2 ankyrin repeat kinase K08253|1|0.0|1759|dme:Dmel_CG18247|non-specific protein-tyrosine kinase [EC:2.7.10.2] GO:0044444//cytoplasmic part GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0006909//phagocytosis;GO:0000165//MAPK cascade;GO:0007392;GO:0003006//developmental process involved in reproduction;GO:0006464//cellular protein modification process 318912 2203.00 0.14 0.185 0.402098443571346 Up 0.0673292827895919 Ir31a ionotropic receptor 31a, isoform D K05313|1|1e-11|71.6|cel:C06A8.9|glutamate receptor, ionotropic, invertebrate;K05204|3|9e-06|52.0|gga:419751|glutamate receptor, ionotropic, kainate 4 GO:0031224//intrinsic to membrane GO:0016301//kinase activity;GO:0008066//glutamate receptor activity;GO:0032559;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 33193 840.15 13.385 11.155 -0.262926625396637 Down 0.357053229428081 CG11555 CG11555, isoform B - - - - 318881 527.00 3.01 2.77 -0.119877510710514 Down 0.106855105005944 CG31680 CG31680 - - - - 41116 1282.00 1.65 1.02 -0.69389687227432 Down 0.255580504556862 CG18473 CG18473 K07048|1|0.0|712|dme:Dmel_CG18473| - GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process 3354863 2732.57 0.77 1.58 1.0369942074822 Up 0.315843349623564 klhl10 klhl10, isoform B K10448|1|0.0|1579|dme:Dmel_CG12423|kelch-like protein 10 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0032446//protein modification by small protein conjugation;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 39943 2053.85 24.09 25.02 0.054647395927349 Up 0.134460441157047 frc fringe connection, isoform B - GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0007472//wing disc morphogenesis;GO:0044267//cellular protein metabolic process;GO:0048592//eye morphogenesis;GO:0006743//ubiquinone metabolic process;GO:0015781//pyrimidine nucleotide-sugar transport;GO:0007365//periodic partitioning;GO:0007472//wing disc morphogenesis;GO:0044267//cellular protein metabolic process;GO:0048592//eye morphogenesis;GO:0015781//pyrimidine nucleotide-sugar transport;GO:0007365//periodic partitioning 42615 1510.22 182.83 138.8 -0.397495249198206 Down 0.595495971470083 sar1 Sar1 ortholog, isoform E K07953|1|4e-111|401|dya:Dyak_GE10286|GTP-binding protein SAR1 [EC:3.6.5.-] GO:0030133//transport vesicle;GO:0030133//transport vesicle;GO:0030133//transport vesicle;GO:0030133//transport vesicle GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0048079;GO:0008363//larval chitin-based cuticle development;GO:0015031//protein transport;GO:0006996//organelle organization;GO:0009790//embryo development;GO:0031345//negative regulation of cell projection organization;GO:0048079;GO:0008363//larval chitin-based cuticle development;GO:0015031//protein transport;GO:0006996//organelle organization;GO:0009790//embryo development;GO:0031345//negative regulation of cell projection organization;GO:0048079;GO:0008363//larval chitin-based cuticle development;GO:0015031//protein transport;GO:0006996//organelle organization;GO:0009790//embryo development;GO:0031345//negative regulation of cell projection organization;GO:0048079;GO:0008363//larval chitin-based cuticle development;GO:0015031//protein transport;GO:0006996//organelle organization;GO:0009790//embryo development;GO:0031345//negative regulation of cell projection organization 36216 947.00 0.33 0.825 1.32192809488736 Up 0.256174877823273 zetaTry zetaTrypsin K01312|1|5e-162|570|dme:Dmel_CG12387|trypsin [EC:3.4.21.4] GO:0044421//extracellular region part GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835379 366.00 0.12 0.165 0.459431618637297 Up 0.0679896975300489 246614 2373.27 13.24 8.83 -0.584417779158752 Down 0.534572711662924 CG30438 CG30438, isoform E K00699|1|4e-66|253|dpo:Dpse_GA19758|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups - 14462551 1229.00 2.06 1.86 -0.147341716075187 Down 0.105204068154801 40450 701.00 7.17 6.36 -0.172946353417549 Down 0.212092193897768 CG7130 CG7130 K09510|1|5e-26|117|dvi:Dvir_GJ11949|DnaJ homolog subfamily B member 4 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process 37483 569.00 2.2 2.62 0.252063288012791 Up 0.167448157442874 Grx-1 Grx-1 K03676|1|1e-61|235|dme:Dmel_CG7975|glutaredoxin 3 - GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis 5740807 590.00 0.08 0.01 -3 Down 0.110718531237617 CG34225 CG34225 - - - - 14462618 871.00 66.865 75.635 0.177802754084411 Up 0.378351604807819 35812 1070.00 12.065 18.18 0.591524283978356 Up 0.571919165235768 CG8701 CG8701 - - - - 318638 2241.00 0.79 0.855 0.114071766708795 Up 0.0625082551842557 CG31231 CG31231 - - - - 19834754 864.00 15.47 16.355 0.0802585626337426 Up 0.164344208162726 31873 2613.13 96.235 44.955 -1.09808010300999 Down 0.730451723682473 CG17754 CG17754, isoform G K10442|1|0.0|1214|dme:Dmel_CG17754|kelch-like protein 1/4/5 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis 5740575 427.00 2.25 2.09 -0.106422059136154 Down 0.0881653678510104 CG34241 CG34241 - - GO:0022892 GO:0051234//establishment of localization 36109 2898.52 97.295 79.98 -0.282726385517626 Down 0.497853652093515 whd withered, isoform D K08765|1|0.0|1595|dme:Dmel_CG12891|carnitine O-palmitoyltransferase 1 [EC:2.3.1.21] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 31287 1187.00 0.135 0.08 -0.754887502163469 Down 0.0813630960243033 CG14423 CG14423 - - - - 43167 657.00 11.985 8.385 -0.515347220084787 Down 0.498547087570995 CG14543 CG14543 - - - - 31700 960.06 831 840.415 0.0162534349350076 Up 0.0937128516708493 RpS6 ribosomal protein S6, isoform B K02991|1|1e-118|426|dme:Dmel_CG10944|small subunit ribosomal protein S6e - - - 43134 2202.00 0.085 0.065 -0.387023123109247 Down 0.0544181746136574 MCO3 multicopper oxidase 3 K00540|1|8e-26|119|cel:F21D5.3| [EC:1.-.-.-] - GO:0015082;GO:0046914//transition metal ion binding;GO:0016682//oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor GO:0008152//metabolic process 35151 511.77 52.98 54.44 0.0392192231343722 Up 0.128153480385682 Nedd8 Nedd8, isoform B K12158|1|2e-41|167|dme:Dmel_CG10679|ubiquitin-like protein Nedd8 - - GO:0007224//smoothened signaling pathway;GO:0006508//proteolysis;GO:0031396//regulation of protein ubiquitination 35158 1839.96 86.135 82.39 -0.0641303374197154 Down 0.174712719587901 CG10641 Swiprosin-1, isoform B K02183|1|5e-09|62.8|mmu:80796|calmodulin;K10840|2|6e-08|59.3|gga:422303|centrin-2 - GO:0046872//metal ion binding GO:0009888//tissue development 34292 2976.00 18.745 17.015 -0.139698674323082 Down 0.259344868577467 zf30C zinc finger protein 30C K09228|1|2e-41|171|bta:515089|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0048468//cell development 37012 5231.61 173.26 191.08 0.141238159521447 Up 0.334367983093383 CG6424 CG6424, isoform D - - - - 50139 469.55 29.99 35 0.222873399850951 Up 0.397569673755118 CG12848 CG12848, isoform B - - - - 39360 6474.00 0.01 0.01 0 - 0.0382380134724607 CG43896 CG43896, isoform D K01873|1|1e-18|96.3|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 246595 1268.00 3.135 2.235 -0.488190611618721 Down 0.288964469686963 CG30403 CG30403 - - GO:0003676//nucleic acid binding - 43825 4076.60 10.775 10.805 0.00401120288304673 Up 0.0427618544445912 sv shaven, isoform I K09383|1|3e-59|231|xla:379520|paired box protein 2/5 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0042675//compound eye cone cell differentiation;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis 40355 522.00 1.375 0.575 -1.25779775746765 Down 0.322678642187294 Cpr78Cc cuticular protein 78Cc - - GO:0005214//structural constituent of chitin-based cuticle - 41493 1767.00 0.11 0.13 0.241008099503795 Up 0.0524039096552635 CG4066 CG4066 - - - - 41978 1670.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 CG17929 CG17929 K08150|1|4e-07|56.6|mmu:239606|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 13;K08149|2|8e-07|55.5|bfo:BRAFLDRAFT_67586|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 12 - - - 38579 1958.00 4.725 4.145 -0.188942227612685 Down 0.18663320565315 CG7509 CG7509 K13023|1|2e-35|150|mcc:707574|carboxypeptidase N regulatory subunit - GO:0005488//binding - 38064 774.00 0.89 0.7 -0.346450414021431 Down 0.123167349095232 CG13884 CG13884 - - - - 318918 3470.50 11.6 13.81 0.251588514243116 Up 0.350581164971602 Kdm4B histone demethylase 4B, isoform E K06709|1|0.0|1028|dme:Dmel_CG33182|jumonji domain-containing protein 2 [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity;GO:0030528//transcription regulator activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity;GO:0030528//transcription regulator activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity;GO:0030528//transcription regulator activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity GO:0070076//histone lysine demethylation;GO:0070076//histone lysine demethylation;GO:0070076//histone lysine demethylation;GO:0070076//histone lysine demethylation 318948 1643.00 1.175 1.555 0.404253823565603 Up 0.179863954563466 Mst36Fa Male-specific transcript 36Fa - - - - 38228 1387.00 3.505 3.555 0.0204351156087922 Up 0.0513472460705323 CG12018 CG12018 K02328|1|0.0|874|dme:Dmel_CG12018|DNA polymerase delta subunit 2 GO:0015630//microtubule cytoskeleton;GO:0042575 GO:0003676//nucleic acid binding;GO:0034061 GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress 42560 640.00 0.955 0.285 -1.74453881387101 Down 0.312310130762119 burs bursicon - GO:0005615//extracellular space GO:0005179//hormone activity GO:0007564//regulation of chitin-based cuticle tanning;GO:0048066//developmental pigmentation 32644 2271.00 7.52 5.07 -0.568746914674297 Down 0.453110553427553 sing singles bar - GO:0031224//intrinsic to membrane - - 39827 1745.83 226.265 247.455 0.12915275583858 Up 0.3195086514331 TMS1 TMS1, isoform F - GO:0044464//cell part - - 19835441 493.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 44390 905.80 450.11 497.605 0.144723364795088 Up 0.34024567428345 RFeSP rieske iron-sulfur protein, isoform E K00411|1|2e-121|434|dse:Dsec_GM16602|ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044425//membrane part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044425//membrane part GO:0043169//cation binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051536//iron-sulfur cluster binding;GO:0016491//oxidoreductase activity;GO:0043169//cation binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051536//iron-sulfur cluster binding;GO:0016491//oxidoreductase activity GO:0022904//respiratory electron transport chain;GO:0007033//vacuole organization;GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain;GO:0007033//vacuole organization;GO:0051234//establishment of localization 35799 15772.02 8.755 9.37 0.0979418692256289 Up 0.157508915598996 LRP1 LDL receptor protein 1, isoform G K04550|1|0.0|9881|dme:Dmel_CG33087|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) GO:0031224//intrinsic to membrane GO:0046872//metal ion binding GO:0006897//endocytosis;GO:0050794//regulation of cellular process;GO:0008152//metabolic process 34404 932.00 0.445 0.44 -0.0163018123291004 Down 0.0382380134724607 pim pimples, isoform B - GO:0043231//intracellular membrane-bounded organelle - GO:0048731;GO:0000819//sister chromatid segregation;GO:0044260;GO:0051301//cell division;GO:0051297//centrosome organization;GO:0051304//chromosome separation;GO:0030855//epithelial cell differentiation;GO:0007067//mitosis 36526 5850.72 34.8 40.23 0.20918443188954 Up 0.392616563201691 stj straightjacket, isoform D K05316|1|0.0|2399|dme:Dmel_CG12295|voltage-dependent calcium channel alpha-2/delta, invertebrate GO:0034704//calcium channel complex - GO:0006906//vesicle fusion;GO:0008582//regulation of synaptic growth at neuromuscular junction 261603 1352.00 1.635 3.475 1.08772234211279 Up 0.454266279223352 CG32445 CG32445 K01785|1|0.0|758|dme:Dmel_CG32445|aldose 1-epimerase [EC:5.1.3.3] - GO:0005488//binding;GO:0003824//catalytic activity GO:0005996//monosaccharide metabolic process 36689 2347.28 13.95 15.12 0.116193017504523 Up 0.214502707700436 CG8079 CG8079, isoform E K13094|1|2e-06|55.1|dvi:Dvir_GJ16951|RNA-binding protein 5/10 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0005488//binding;GO:0005488//binding GO:0000377;GO:0000377 38552 1970.00 0.045 0.025 -0.84799690655495 Down 0.0552767137762515 CG11349 CG11349 - - - - 40390 410.96 544.17 599.33 0.139293167861901 Up 0.340972130497953 CoVIII cytochrome c oxidase subunit VIII, isoform B K02273|1|4e-33|139|dme:Dmel_CG7181|cytochrome c oxidase subunit VIII [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity - 34757 2963.49 3.76 5.29 0.492535060436388 Up 0.367884031171576 CG7110 CG7110, isoform C - - - - 31059 1638.00 0.785 0.825 0.0717014653541888 Up 0.0525359926033549 eIF4E-7 eIF4E-7 K03259|1|5e-73|275|dmo:Dmoj_GI14982|translation initiation factor eIF-4E - - - 33512 1714.00 18.535 19.72 0.0894074365587556 Up 0.187590807026813 alpha4GT1 alpha4GT1 K01988|1|0.0|727|dme:Dmel_CG17223|lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228] GO:0044431//Golgi apparatus part GO:0008376//acetylgalactosaminyltransferase activity GO:0008593//regulation of Notch signaling pathway;GO:0006687//glycosphingolipid metabolic process 37592 575.00 2.24 5.91 1.39965939811993 Up 0.582089552238806 CG30195 CG30195 - - - - 14462836 1430.00 12.835 12.385 -0.0514894273290551 Down 0.112567692510897 CG43781 CG43781, isoform B - - - - 42956 2690.00 8.62 8.185 -0.0747054526149447 Down 0.122771100250958 CG5807 CG5807, isoform B - - - - 32572 2630.00 25.435 24.185 -0.0727025564167662 Down 0.168570862501651 dpr18 dpr18 - - - - 37360 1981.11 4.22 8.455 1.0025617557028 Up 0.578688416325452 Ipk1 Ipk1, isoform D K10572|1|0.0|921|dme:Dmel_CG30295|inositol-pentakisphosphate 2-kinase [EC:2.7.1.158] - - - 14462624 682.00 0.235 0.135 -0.799701349514169 Down 0.101637828556333 44129 5194.67 5.775 5.715 -0.0150674480889418 Down 0.0528001584995377 hbs hibris, isoform C K06768|1|4e-34|147|dpo:Dpse_GA14672|Down syndrome cell adhesion molecule like 1 GO:0044464//cell part;GO:0044464//cell part - GO:0014706//striated muscle tissue development;GO:0048592//eye morphogenesis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0014706//striated muscle tissue development;GO:0048592//eye morphogenesis;GO:0000768//syncytium formation by plasma membrane fusion 37143 1376.81 24.39 27.165 0.15545928887514 Up 0.308743891163651 Eip55E Eip55E, isoform B K01758|1|0.0|775|dme:Dmel_CG5345|cystathionine gamma-lyase [EC:4.4.1.1] - - - 318553 758.00 1.35 2.435 0.850962365031512 Up 0.349062211068551 CG31007 CG31007 - - - - 50050 1934.00 17.915 21.595 0.269529272996286 Up 0.413023378681812 CG17278 CG17278 - - - - 32144 1776.00 18.98 19.525 0.040842556008232 Up 0.109859992075023 CG1847 CG1847, isoform C K09571|1|8e-14|79.0|bta:508535|FK506-binding protein 4/5 [EC:5.2.1.8] - - GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 36405 1452.27 55.975 47.465 -0.237918539923708 Down 0.439373926826047 Taz tafazzin, isoform D K13511|1|0.0|702|dme:Dmel_CG8766|monolysocardiolipin acyltransferase [EC:2.3.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032576;GO:0032576;GO:0032576;GO:0032576 GO:0003006//developmental process involved in reproduction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0003006//developmental process involved in reproduction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0003006//developmental process involved in reproduction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0003006//developmental process involved in reproduction;GO:0006655//phosphatidylglycerol biosynthetic process 40552 1332.01 131.915 118.725 -0.151984865976261 Down 0.34592524105138 CG11739 CG11739, isoform D K03351|1|4e-88|325|smm:Smp_136960|anaphase-promoting complex subunit 4 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport 36496 2402.82 60.42 58.58 -0.0446179908485741 Down 0.13079513934751 bbc bb in a boxcar, isoform E K00993|1|0.0|776|der:Dere_GG22487|ethanolaminephosphotransferase [EC:2.7.8.1] GO:0044464//cell part;GO:0044464//cell part GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process 5740715 479.00 35.905 31.61 -0.183803727271652 Down 0.351868973715493 CG34191 CG34191, isoform B K12162|1|4e-43|173|dme:Dmel_CG34191|ubiquitin-fold modifier 1 GO:0043231//intracellular membrane-bounded organelle - GO:0032446//protein modification by small protein conjugation 37640 1183.00 28.895 29.015 0.00597905897775212 Up 0.0563994188350284 CG3700 CG3700 K01320|1|8e-29|127|tgu:100223776|coagulation factor VII [EC:3.4.21.21];K01324|2|2e-27|123|bta:533547|plasma kallikrein [EC:3.4.21.34];K08648|5|5e-26|118|mmu:226243|hyaluronan binding protein 2 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 12798395 575.00 0.01 0.24 4.58496250072116 Up 0.234975564654603 CG43396 CG43396 - - - - 19836178 1591.00 1.09 2.1 0.946061192889196 Up 0.342590146612072 19834787 246.00 0.625 1.415 1.1788739581698 Up 0.317692510896843 2768870 1133.00 4.495 3.315 -0.43931224540186 Down 0.322051248183859 AlkB AlkB K10765|1|1e-56|220|bfo:BRAFLDRAFT_119815|alkylated DNA repair protein alkB homolog 1 - - - 39565 2210.11 0.875 0.865 -0.0165828841956042 Down 0.0413749834896315 CG8100 CG8100, isoform B - - GO:0022892 GO:0051234//establishment of localization 2768899 607.00 0.11 0.015 -2.87446911791614 Down 0.12511557257958 Ste:CG33241 Ste:CG33241 K08282|1|1e-95|348|dme:Dmel_CG33241|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 250710 1907.55 52.9 45.11 -0.229820436282035 Down 0.426826046757364 Proct proctolin, isoform B - - - - 12798044 529.00 8.455 8.015 -0.0771022342554351 Down 0.128285563333774 CG43448 CG43448 - - - - 39397 1491.00 1.48 1.53 0.047934477063702 Up 0.0546493197728173 CG5626 CG5626 - - GO:0016301//kinase activity;GO:0032559 GO:0006139//nucleobase-containing compound metabolic process 47216 2359.00 1.565 1.39 -0.171077774209111 Down 0.0996896050719852 Klp54D Kinesin-like protein at 54D, isoform C K10399|1|4e-78|293|mdo:100009978|kinesin family member 12 GO:0005875//microtubule associated complex;GO:0019897//extrinsic to plasma membrane GO:0060089;GO:0003774//motor activity;GO:0032559 GO:0007166//cell surface receptor signaling pathway;GO:0007017//microtubule-based process;GO:0023060 34471 1164.00 620.935 792.025 0.351103715387377 Up 0.576971338000264 CG17108 CG17108 - - - - 33176 5304.21 3.71 4.29 0.209558460878742 Up 0.190760797781006 CG42399 CG42399, isoform C - - - - 33361 5502.79 54.63 67.515 0.305514642408713 Up 0.514397041341963 wry weary, isoform D K06051|1|2e-70|268|bfo:BRAFLDRAFT_123438|delta;K02599|3|5e-69|264|tca:661022|Notch - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 34139 1320.00 10.555 10.32 -0.0324836079239018 Down 0.0789195614846123 CG7810 CG7810 - - - - 39928 901.00 1.295 1.83 0.498891550597489 Up 0.222163518689737 CG13725 CG13725 - - GO:0032559 - 43319 2097.00 16.89 15.835 -0.0930524607731958 Down 0.182076343943997 Mtl Mig-2-like, isoform C K04392|1|2e-101|369|cqu:CpipJ_CPIJ013262|Ras-related C3 botulinum toxin substrate 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding GO:0016477//cell migration;GO:0007015//actin filament organization;GO:0000165//MAPK cascade;GO:0033554//cellular response to stress;GO:0007392;GO:0007431//salivary gland development;GO:0030031//cell projection assembly;GO:0016477//cell migration;GO:0007015//actin filament organization;GO:0000165//MAPK cascade;GO:0033554//cellular response to stress;GO:0007392;GO:0007431//salivary gland development;GO:0030031//cell projection assembly;GO:0016477//cell migration;GO:0007015//actin filament organization;GO:0000165//MAPK cascade;GO:0033554//cellular response to stress;GO:0007392;GO:0007431//salivary gland development;GO:0030031//cell projection assembly 38806 1933.00 0.855 0.075 -3.51096191927738 Down 0.377394003434157 RhoGEF4 Rho guanine nucleotide exchange factor 4, isoform B K05723|1|8e-23|108|mmu:224014|FYVE, RhoGEF and PH domain containing 4 GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089 GO:0065008;GO:0007266//Rho protein signal transduction;GO:0065008;GO:0007266//Rho protein signal transduction 317938 619.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG32248 CG32248 - - - - 36488 4579.75 54.39 56.69 0.0597528433541123 Up 0.169000132082948 CG42321 CG42321, isoform S K01530|1|0.0|2058|dsi:Dsim_GD25762|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559 GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport 31435 2124.00 0.25 0.395 0.659924558402379 Up 0.118478404437987 CG5062 CG5062 - - - - 8674084 1950.27 0.53 1.02 0.944504887408296 Up 0.240589089948488 CG42524 CG42524, isoform C - - - - 44219 2043.00 0.045 0.065 0.53051471669878 Up 0.0549134856690001 Sr-CII scavenger receptor class C, type II, isoform B K01316|1|8e-12|72.4|oaa:100079480|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K05119|2|1e-08|62.0|ame:408718|anaplastic lymphoma kinase [EC:2.7.10.1];K06724|3|1e-08|62.0|dre:353246|neuropilin 1 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0001871;GO:0004888//transmembrane signaling receptor activity;GO:0001871;GO:0004888//transmembrane signaling receptor activity GO:0006950//response to stress;GO:0002376//immune system process;GO:0006950//response to stress;GO:0002376//immune system process 43056 1415.00 15.11 16.32 0.111137396806667 Up 0.208823140932506 CG11893 CG11893 - - - - 43305 1919.00 0.105 0.03 -1.8073549220576 Down 0.10183595297847 Gr98a gustatory receptor 98a K08471|1|0.0|782|dme:Dmel_CG13976|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33229 4324.35 3.125 2.6 -0.265344566520995 Down 0.191817461365738 Ets21C Ets at 21C, isoform D K09443|1|6e-180|630|dse:Dsec_GM16660|ETS-type family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent 38865 4429.00 1.575 1.075 -0.551015168797818 Down 0.219125610883635 CG7457 CG7457 K09257|1|0.0|2614|dme:Dmel_CG7457|nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39213 1575.00 17.28 17.26 -0.00167075298451375 Down 0.0416061286487914 CG11811 CG11811 K00942|1|3e-119|428|dme:Dmel_CG11811|guanylate kinase [EC:2.7.4.8] GO:0044424//intracellular part GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559 GO:0009117//nucleotide metabolic process 40840 2138.07 1.835 2.61 0.508269743726672 Up 0.26958129705455 CG1988 CG1988, isoform D - - - - 326176 2076.00 0.115 0.105 -0.131244533278252 Down 0.0444459120327566 CG31933 CG31933 - - - - 41706 1640.00 255.875 164.56 -0.636825498273201 Down 0.68118478404438 Cyp6d5 Cyp6d5 K00517|1|1e-140|499|dme:Dmel_CG12800| [EC:1.14.-.-];K07424|4|4e-85|315|tca:659054|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] - - - 31378 1489.00 0.53 0.125 -2.08406426478847 Down 0.245905428609167 CG12688 CG12688 - - - - 35786 1840.00 19.58 20.16 0.0421148738962217 Up 0.11144498745212 Socs44A suppressor of cytokine signaling at 44A K04700|1|4e-166|584|dme:Dmel_CG2160|suppressor of cytokine signaling, invertebrate - GO:0005488//binding GO:0035468;GO:0010741//negative regulation of intracellular protein kinase cascade 44811 8524.85 27.775 30.51 0.135495268302202 Up 0.288138951261392 E(bx) enhancer of bithorax, isoform J K11728|1|0.0|3291|dme:Dmel_CG32346|nucleosome-remodeling factor subunit BPTF GO:0031010;GO:0031010;GO:0031010;GO:0031010;GO:0031010 GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding GO:0016568//chromatin modification;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0048534;GO:0048812//neuron projection morphogenesis;GO:0034728//nucleosome organization;GO:0010467//gene expression;GO:0016568//chromatin modification;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0048534;GO:0048812//neuron projection morphogenesis;GO:0034728//nucleosome organization;GO:0010467//gene expression;GO:0016568//chromatin modification;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0048534;GO:0048812//neuron projection morphogenesis;GO:0034728//nucleosome organization;GO:0010467//gene expression;GO:0016568//chromatin modification;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0048534;GO:0048812//neuron projection morphogenesis;GO:0034728//nucleosome organization;GO:0010467//gene expression;GO:0016568//chromatin modification;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0048534;GO:0048812//neuron projection morphogenesis;GO:0034728//nucleosome organization;GO:0010467//gene expression 261599 1467.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 mthl12 methuselah-like 12 K04599|1|1e-83|310|dpo:Dpse_GA19967|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus 42187 2619.00 5.615 6.505 0.212263034317194 Up 0.233720776647735 CG7156 CG7156, isoform B K06069|1|2e-07|58.2|cqu:CpipJ_CPIJ013835|atypical protein kinase C [EC:2.7.11.13] - - - 19835068 543.00 0.08 0.09 0.169925001442312 Up 0.045667679302602 34268 5321.23 18.905 20.79 0.137121908871135 Up 0.265123497556465 Oatp30B organic anion transporting polypeptide 30B, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008509//anion transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity GO:0006820//anion transport;GO:0006820//anion transport;GO:0006820//anion transport;GO:0006820//anion transport 38088 1302.86 7.64 14.185 0.89272160723861 Up 0.616827367586845 CkIIalpha-i3 CKII-alpha subunit interactor-3, isoform C - - - - 317953 1539.00 6.005 4.335 -0.470132252483799 Down 0.378483687755911 CG32281 CG32281 K07055|1|0.0|904|dme:Dmel_CG32281| - GO:0008173//RNA methyltransferase activity GO:0000096//sulfur amino acid metabolic process 32492 1027.37 9.74 10.385 0.0925075387623054 Up 0.154735173689077 cerv cervantes, isoform D - - - - 43841 10327.97 112.18 144.51 0.365353841626348 Up 0.576740192841104 unc-13 unc-13, isoform G K08267|1|1e-35|154|spu:591989|rapamycin-insensitive companion of mTOR;K02677|2|7e-16|88.6|bta:282002|classical protein kinase C [EC:2.7.11.13] - - - 42587 2679.94 97.45 99.735 0.0334376929157164 Up 0.112270505877691 CG6455 CG6455, isoform E - GO:0031304//intrinsic to mitochondrial inner membrane - - 59184 667.00 0.07 0.205 1.55019708256048 Up 0.13079513934751 CG18823 CG18823 - GO:0016020//membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0009987//cellular process 36467 1008.00 80.875 47.43 -0.769893938687705 Down 0.689506009774138 GstE14 glutathione S transferase E14 K00799|1|5e-130|463|dme:Dmel_CG4688|glutathione S-transferase [EC:2.5.1.18] - - - 3885588 946.00 1.885 5.105 1.43734643760914 Up 0.564984810460969 CG33460 CG33460 K01314|1|7e-15|81.3|tgu:100221743|coagulation factor X [EC:3.4.21.6];K09632|2|2e-13|76.6|mdo:100021711|chymotrypsin-like protease [EC:3.4.21.-];K09634|4|4e-13|75.5|cfa:610987|transmembrane protease, serine 3 [EC:3.4.21.-];K01320|5|6e-13|74.7|xla:444394|coagulation factor VII [EC:3.4.21.21] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41194 2218.72 0.37 1.225 1.72718457337362 Up 0.350746268656716 CG8478 CG8478, isoform E - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 31511 1077.00 0.505 0.245 -1.04350163863659 Down 0.174151367058513 Prosbeta2R1 proteasome beta2 subunit-related 1 K02739|1|7e-176|616|dme:Dmel_CG18341|20S proteasome subunit beta 2 [EC:3.4.25.1] - - - 19835893 487.00 0.09 0.12 0.415037499278844 Up 0.0616827367586845 33465 3586.00 5.34 5.23 -0.0300287954406125 Down 0.0633998150838727 Trn-SR Transportin-Serine/Arginine rich, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0022892 GO:0043484//regulation of RNA splicing;GO:0006606//protein import into nucleus;GO:0006405//RNA export from nucleus 36663 1964.00 30.725 33.905 0.142085033952165 Up 0.295205388984282 Cyp6a9 cytochrome P450-6a9 K00517|1|0.0|991|dme:Dmel_CG10246| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 35421 5311.16 17.145 22.41 0.386354744574759 Up 0.505349359397702 CG2225 CG2225, isoform H - - - - 41566 1469.00 86.51 83.51 -0.0509179435724366 Down 0.153414344208163 Arp1 Actin-related protein 1 K05692|1|2e-118|426|smm:Smp_046590|actin beta/gamma 1 - - - 43057 1487.00 24.46 21.54 -0.183406153983179 Down 0.330240390965526 CG31098 CG31098 - - - - 5740730 1088.00 1.795 1.815 0.0159857041726994 Up 0.0440166424514595 19835157 936.00 0.92 0.705 -0.384010603658219 Down 0.130630035662396 42576 1542.00 54.25 109.935 1.01895572749036 Up 0.727083608506142 CG6656 CG6656 K01078|1|3e-158|558|dme:Dmel_CG6656|acid phosphatase [EC:3.1.3.2] - GO:0016791//phosphatase activity - 31686 1845.00 0.085 0.145 0.770518153877233 Up 0.0813630960243033 Ir7a ionotropic receptor 7a - - - - 36259 1343.00 8.97 10.82 0.270520608907554 Up 0.340377757231541 CG13192 CG13192 - - - - 37107 890.00 42.44 35.91 -0.241039003250107 Down 0.427552502971866 GstE2 glutathione S transferase E2 K00799|1|2e-125|448|dme:Dmel_CG17523|glutathione S-transferase [EC:2.5.1.18] - - - 42606 2876.32 29.12 28.265 -0.0429936585432791 Down 0.11966715097081 CG7084 CG7084, isoform F K08202|1|6e-50|199|bfo:BRAFLDRAFT_257702|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 31628 3686.66 12.22 13.865 0.182203331220749 Up 0.28325188218201 CG14435 CG14435, isoform C K10694|1|5e-56|220|dse:Dsec_GM12546|E3 ubiquitin-protein ligase ZNRF [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 34513 545.62 1.725 1.665 -0.0510741845942693 Down 0.0566966054682341 CG14072 CG14072, isoform C - - - - 50026 447.00 0.59 1.055 0.838456139345344 Up 0.226324131554616 CG14374 CG14374 - - - - 42095 1222.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 CG5860 CG5860 K01379|1|9e-61|234|dgr:Dgri_GH21578|cathepsin D [EC:3.4.23.5] - - - 43781 4549.62 8.325 9.7 0.220534475115865 Up 0.28648791441025 RhoGAP102A Rho GTPase activating protein at 102A, isoform F K08878|1|2e-18|95.1|nve:NEMVE_v1g239294|breakpoint cluster region protein [EC:2.7.11.1];K10360|2|3e-16|88.2|cin:100177964|myosin IX - - - 47384 1856.43 60.275 59.535 -0.0178216827688994 Down 0.0865803724739136 sra sarah, isoform B - - GO:0005488//binding GO:0060180//female mating behavior;GO:0007126//meiosis;GO:0001775//cell activation;GO:0007613//memory;GO:0019932//second-messenger-mediated signaling;GO:0045297//post-mating behavior;GO:0006997//nucleus organization;GO:0008306//associative learning 34784 2193.59 2.405 2.82 0.229658268628752 Up 0.164872539955092 CG16863 CG16863, isoform B K13354|1|8e-08|59.3|nvi:100116581|solute carrier family 25 member 17 GO:0044464//cell part;GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 37540 1737.00 0.07 0.195 1.47804729680464 Up 0.121054021925769 CG3264 CG3264, isoform B K01077|1|0.0|1042|dme:Dmel_CG3264|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 38468 6214.33 21.235 26.625 0.326337416653161 Up 0.482003698322547 CG12605 CG12605, isoform E K09219|1|3e-67|258|bfo:BRAFLDRAFT_115417|scratch GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 38203 1191.14 63.835 64.825 0.0222026469760459 Up 0.0880993263769647 CG13920 CG13920, isoform C - - - - 42986 4475.94 14.38 14.95 0.0560818086461697 Up 0.128945978074231 ssh slingshot, isoform D K05766|1|0.0|1832|dse:Dsec_GM23443|slingshot - GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity GO:0001654//eye development;GO:0030032//lamellipodium assembly;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0030832//regulation of actin filament length;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0030032//lamellipodium assembly;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0030832//regulation of actin filament length;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0030032//lamellipodium assembly;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0030832//regulation of actin filament length;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0030032//lamellipodium assembly;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0030832//regulation of actin filament length;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process 43161 769.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 E(spl)m8-HLH enhancer of split m8, helix-loop-helix K09090|1|3e-91|333|dme:Dmel_CG8365|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016564//transcription repressor activity GO:0009888//tissue development;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007389//pattern specification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001654//eye development;GO:0001709//cell fate determination;GO:0007476//imaginal disc-derived wing morphogenesis 33573 1695.44 37.785 36.62 -0.04518183165806 Down 0.140073966450931 CG17593 CG17593, isoform B - - - - 7354421 1498.00 10.995 8.935 -0.299307969813478 Down 0.368115176330736 CG42358 CG42358 - - - - 39102 1247.09 45.21 22.22 -1.02478310092989 Down 0.706610751551975 Uch-L3 ubiquitin carboxy-terminal hydrolase L5 ortholog, isoform B K05610|1|0.0|659|dme:Dmel_CG3431|ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12] GO:0022624//proteasome accessory complex GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process 40011 699.00 26.265 12.51 -1.07005979498889 Down 0.685807687227579 CheA75a chemosensory protein A 75a - - - - 4379870 2738.29 2.47 2.21 -0.160464672193246 Down 0.120030379078061 CG34141 CG34141, isoform E K06071|1|0.0|1078|dsi:Dsim_GD10089|protein kinase N [EC:2.7.11.13] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0023060;GO:0006464//cellular protein modification process;GO:0023060;GO:0006464//cellular protein modification process;GO:0023060 32701 1001.31 214.575 217.495 0.0195002367946577 Up 0.0920287940826839 CG5010 CG5010, isoform B K11837|1|4e-11|68.9|bfo:BRAFLDRAFT_121867|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K06975|2|2e-06|53.1|cfa:609617| - - - 19834881 357.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 34889 5933.89 14.315 19.945 0.47849945308781 Up 0.539558842953375 CG4168 CG4168, isoform C K05401|1|3e-36|155|dme:Dmel_CG5195|toll-like recepto 3 - GO:0005488//binding - 33554 838.29 13.55 13.27 -0.0301244808710406 Down 0.0846321489895654 CG9662 CG9662, isoform B - - - - 37746 1987.13 206.68 239.06 0.209973966731391 Up 0.436831330075287 Pal2 Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2, isoform E K00504|1|5e-60|232|ame:408568|peptidylglycine monooxygenase [EC:1.14.17.3] GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016842;GO:0046914//transition metal ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016842 GO:0007126//meiosis;GO:0044237//cellular metabolic process;GO:0007126//meiosis;GO:0044237//cellular metabolic process 39888 1826.00 9.96 8.99 -0.147824626553634 Down 0.219191652357681 CG9951 CG9951 K10352|1|7e-07|55.8|bmy:Bm1_50805|myosin heavy chain;K11498|2|1e-06|55.1|gga:422716|centromeric protein E - - - 326152 2941.98 5.775 5.71 -0.016330200940577 Down 0.0528001584995377 erm earmuff, isoform C K09228|1|1e-48|195|ptr:737637|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 326128 2279.26 6.215 7.49 0.269211327406266 Up 0.295865803724739 Ada2a transcriptional adaptor 2a, isoform G K11314|1|0.0|1073|dsi:Dsim_GD20190|transcriptional adapter 2-alpha GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter 43586 3775.00 4.025 1.995 -1.01260003677963 Down 0.467276449610355 CG31028 CG31028 K04565|1|5e-06|54.3|cel:C15F1.7|Cu/Zn superoxide dismutase [EC:1.15.1.1] GO:0033176 GO:0043169//cation binding;GO:0015078//hydrogen ion transmembrane transporter activity GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0006754//ATP biosynthetic process 44409 3099.66 13.605 11.59 -0.231256390243207 Down 0.331495178972395 Cbp80 cap binding protein 80, isoform B K12882|1|0.0|1522|dme:Dmel_CG7035|nuclear cap-binding protein subunit 1 GO:0031981//nuclear lumen;GO:0034518//RNA cap binding complex;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0034518//RNA cap binding complex;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0003723//RNA binding GO:0006413//translational initiation;GO:0016246//RNA interference;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0031124//mRNA 3'-end processing;GO:0000398//mRNA splicing, via spliceosome;GO:0045069//regulation of viral genome replication;GO:0006405//RNA export from nucleus;GO:0006413//translational initiation;GO:0016246//RNA interference;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0031124//mRNA 3'-end processing;GO:0000398//mRNA splicing, via spliceosome;GO:0045069//regulation of viral genome replication;GO:0006405//RNA export from nucleus 39865 1390.96 0.36 0.795 1.14295795384204 Up 0.234744419495443 CG9692 CG9692, isoform C - - - - 318961 438.26 10.12 12.83 0.342311880395372 Up 0.417712323339057 CG31820 CG31820, isoform B - - - - 35008 1506.27 422.51 352.82 -0.260053143608416 Down 0.495046889446572 Cyt-b5-r cytochrome b5-related, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005506//iron ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0006631//fatty acid metabolic process 39324 1170.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 Gr68a gustatory receptor 68a K08471|1|0.0|709|dme:Dmel_CG7303|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38093 4287.03 14.525 17.1 0.235458161481369 Up 0.36167613261128 CG13900 CG13900, isoform C K12830|1|0.0|2466|dse:Dsec_GM14250|splicing factor 3B subunit 3 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0005488//binding GO:0000278//mitotic cell cycle;GO:0000377 40331 1475.76 18.765 26.385 0.491673693306141 Up 0.567494386474706 CG10566 CG10566, isoform B - - - - 35064 2787.00 0.135 0.255 0.917537839808027 Up 0.113492273147537 CG15145 CG15145 - - - - 10178834 2591.00 0.035 0.075 1.09953567355091 Up 0.0725795799762251 40810 1013.00 1.07 1.49 0.477701534061015 Up 0.195119535068023 CG15177 CG15177, isoform B - - GO:0046872//metal ion binding - 41749 6181.65 22.735 21.23 -0.0988106328391622 Down 0.210540219257694 cv-c crossveinless c, isoform D K08878|1|5e-12|74.3|nve:NEMVE_v1g239294|breakpoint cluster region protein [EC:2.7.11.1];K08773|2|9e-12|73.6|tad:TRIADDRAFT_59627|RalA-binding protein 1;K13736|3|2e-11|72.8|bta:510704|Rho GTPase-activating protein 10 - - - 39973 1814.00 1.395 0.795 -0.811238356544832 Down 0.258750495311055 CG7460 CG7460, isoform C K12259|1|4e-47|189|tgu:100232049|spermine oxidase [EC:1.5.3.16] - - - 33829 641.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 Vm26Aa vitelline membrane 26Aa, isoform B - GO:0030312//external encapsulating structure - - 34788 1326.12 5.84 6.505 0.155580687837778 Up 0.189836217144367 CG16865 CG16865, isoform B - GO:0005681//spliceosomal complex - GO:0000377 14462360 601.00 10.765 0.905 -3.57228671708403 Down 0.762911108175934 33414 1742.22 4 2.575 -0.635427567704144 Down 0.373200369832255 CG9967 CG9967, isoform C K03495|1|8e-10|65.5|ame:410941|glucose inhibited division protein A - - - 37775 1565.22 51.135 45.88 -0.156445708845278 Down 0.337570994584599 CG5554 CG5554, isoform B K13984|1|3e-14|80.1|tgu:100230544|thioredoxin domain-containing protein 5;K09585|3|9e-14|78.6|cin:100185726|thioredoxin domain-containing protein 10 [EC:5.3.4.1] GO:0031224//intrinsic to membrane GO:0016853//isomerase activity GO:0019725//cellular homeostasis 36010 3509.00 0.315 0.495 0.652076696579693 Up 0.129804517236825 dila dilatory, isoform E K11498|1|6e-17|90.5|mdo:100013897|centromeric protein E;K10352|4|9e-17|89.7|mcc:721979|myosin heavy chain GO:0005737//cytoplasm;GO:0005737//cytoplasm - - 34241 936.00 29.52 34.13 0.209347693038469 Up 0.383866067890635 CG9586 CG9586, isoform C - - - - 5740346 345.00 1.535 0.01 -7.26209484537018 Down 0.599821688020077 38558 1861.13 0.235 0.195 -0.269186632815389 Down 0.0637300224541012 NT1 neurotrophin 1, isoform H - - - - 40847 1923.33 17.905 19.26 0.105245184522935 Up 0.215328226126007 CG1091 CG1091, isoform C K13291|1|3e-16|87.0|mmu:214290|terminal uridylyltransferase [EC:2.7.7.52] - - - 38169 2101.12 0.67 0.775 0.210035214816465 Up 0.0858208955223881 stet stem cell tumor, isoform B K02857|1|1e-178|626|dme:Dmel_CG33166|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0004175//endopeptidase activity GO:0023060;GO:0023060 43178 2161.00 2.89 0.49 -2.56021583838547 Down 0.555177651565183 CG6142 CG6142 K00108|1|4e-159|561|dme:Dmel_CG9518|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 32078 2844.00 12.96 14.05 0.116504412223664 Up 0.209648659358077 dsh dishevelled K02353|1|0.0|877|dme:Dmel_CG18361|dishevelled GO:0070161;GO:0044424//intracellular part GO:0005102//receptor binding;GO:0005543//phospholipid binding GO:0033036;GO:0003129;GO:0007166//cell surface receptor signaling pathway;GO:0048073//regulation of eye pigmentation;GO:0051017//actin filament bundle assembly;GO:0001752//compound eye photoreceptor fate commitment;GO:0030035//microspike assembly;GO:0008406//gonad development;GO:0035151//regulation of tube size, open tracheal system;GO:0019827//stem cell maintenance;GO:0003002//regionalization;GO:0007392;GO:0007292//female gamete generation;GO:0030859//polarized epithelial cell differentiation;GO:0048588//developmental cell growth;GO:0007431//salivary gland development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048104//establishment of body hair or bristle planar orientation 318040 621.00 2.6 1.485 -0.808048692227689 Down 0.350515123497556 CG32457 CG32457, isoform C - - - - 37741 4633.81 18.15 20.51 0.176357943596739 Up 0.314819706775855 Pde8 phosphodiesterase 8, isoform O K01120|1|0.0|1393|dpo:Dpse_GA18863|3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17] - GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004871//signal transducer activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0023060 3355011 1894.43 36.665 36.81 0.00569421034357908 Up 0.0581825386342623 CG17683 CG17683, isoform E - - GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding GO:0031163;GO:0031163;GO:0031163;GO:0031163 35488 1241.00 43.275 41.625 -0.0560835474080142 Down 0.162957337207766 CG10465 CG10465 - GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005267//potassium channel activity;GO:0004112//cyclic-nucleotide phosphodiesterase activity GO:0030001//metal ion transport 36457 988.00 9.735 7.905 -0.300415516361924 Down 0.353156782459384 CG4627 CG4627 - GO:0044464//cell part - - 3772166 595.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 His2B:CG33892 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 38076 1570.32 134.2 84.605 -0.66556983993545 Down 0.678278959186369 Gale UDP-galactose 4'-epimerase, isoform B K01784|1|0.0|721|dme:Dmel_CG12030|UDP-glucose 4-epimerase [EC:5.1.3.2] - GO:0048037//cofactor binding;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives GO:0019318//hexose metabolic process 31812 860.00 14.325 14.745 0.0416906834174696 Up 0.103321886144499 CG1789 CG1789 - GO:0043234//protein complex;GO:0030684//preribosome GO:0005488//binding;GO:0004842//ubiquitin-protein ligase activity GO:0019941//modification-dependent protein catabolic process;GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0032446//protein modification by small protein conjugation 37570 8425.00 1.615 1.6 -0.0134622598065624 Down 0.041044776119403 CG4554 CG4554 - - - - 33220 1488.00 33.605 28.915 -0.216857801672538 Down 0.393012812045965 CG4164 CG4164 K09517|1|0.0|665|dme:Dmel_CG4164|DnaJ homolog subfamily B member 11 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process 39583 5157.71 13.995 10.94 -0.355298748780358 Down 0.438845595033681 bbg big bang, isoform K K06092|1|6e-14|81.6|dre:368723|InaD-like protein GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 38660 1787.00 0.65 0.655 0.0110551885089957 Up 0.041044776119403 CG13287 CG13287, isoform B - - GO:0005488//binding - 33787 1179.00 0.33 0.37 0.165059246270496 Up 0.0603288865407476 CG14017 CG14017 - - - - 41605 4337.00 14.67 15.84 0.11070346440622 Up 0.206247523444723 ry rosy K00106|1|0.0|2674|dme:Dmel_CG7642|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] - - - 318942 349.00 5.92 13.115 1.14754872663603 Up 0.646281865011227 CG31788 CG31788, isoform B - - - - 35180 571.00 8.245 9.015 0.128807997994874 Up 0.190991942940166 CG17343 CG17343 - - - - 37996 959.68 40.605 39.83 -0.0278019085719339 Down 0.10345396909259 CG3776 CG3776, isoform C - - - - 38163 1952.00 0.43 0.155 -1.47206844431522 Down 0.191355171047418 CG9168 CG9168 - - - - 41817 6684.25 24.745 26.6 0.104289203521549 Up 0.220941751419892 CG42788 CG42788, isoform C K05404|1|1e-40|169|dre:403129|toll-like receptor 7;K05633|2|1e-11|73.6|nve:NEMVE_v1g158690|atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:6.3.2.19];K06112|3|2e-11|72.8|ecb:100064709|membrane-associated guanylate kinase-related GO:0043232 GO:0005488//binding GO:0023060 32747 2330.00 0.9 1.13 0.328325866085513 Up 0.132908466516973 CG12990 CG12990 - - GO:0016746//transferase activity, transferring acyl groups - 37946 677.75 179.64 189.85 0.0797513717268786 Up 0.22011623299432 CG3683 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, isoform D K03952|1|7e-102|369|dsi:Dsim_GD11890|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 8 [EC:1.6.5.3 1.6.99.3] - GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 37466 407.15 467.56 389.4 -0.263898627783065 Down 0.495938449346189 CG10320 CG10320, isoform E K03959|1|2e-46|183|dme:Dmel_CG10320|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 39984 4071.00 5.41 5.265 -0.0391950628010985 Down 0.0723484348170651 Grd glycine receptor K05180|1|6e-69|262|ptr:471725|gamma-aminobutyric acid (GABA) A receptor alpha-6;K05270|2|8e-58|225|dpo:Dpse_GA24024|gamma-aminobutyric acid (GABA) receptor, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0016917//GABA receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 40298 1135.00 0.24 0.42 0.807354922057604 Up 0.135979395060098 CG3698 CG3698 - - - - 34385 1878.97 119.16 130.32 0.129158480275988 Up 0.31290450402853 Cdk5alpha Cdk5 activator-like protein, isoform B K11716|1|0.0|838|dme:Dmel_CG5387|cyclin-dependent kinase 5 activator 1 GO:0043005//neuron projection;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0044297//cell body;GO:0030427//site of polarized growth GO:0043539//protein serine/threonine kinase activator activity GO:0007411//axon guidance;GO:0010259//multicellular organismal aging;GO:0007626//locomotory behavior;GO:0006464//cellular protein modification process 7354400 1774.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 Ir60b ionotropic receptor 60b - - - - 3885584 637.00 6.875 15.12 1.13702652092169 Up 0.656848500858539 CG34034 CG34034 - - - - 41851 479.04 23.88 26.395 0.144461829405823 Up 0.283615110289262 l(3)neo43 lethal (3) neo43, isoform C - - - - 33681 3923.06 49.74 55.85 0.167150773153771 Up 0.35507198520671 CG15628 CG15628, isoform B - - GO:0016407//acetyltransferase activity - 34771 1293.00 0.505 0.595 0.236606280556149 Up 0.0815612204464404 CG16853 CG16853, isoform B - - - - 2768722 1362.00 0.375 1.29 1.78240856492737 Up 0.362633733984943 ppk25 pickpocket 25 K04832|1|2e-07|57.0|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04831|4|1e-06|54.3|dre:407668|amiloride-sensitive cation channel 4, pituitary GO:0044464//cell part GO:0005261//cation channel activity GO:0010033//response to organic substance;GO:0030001//metal ion transport;GO:0007619//courtship behavior 35773 1105.21 12.4 12.07 -0.0389144445192161 Down 0.0959582617884031 slv saliva, isoform C - GO:0031224//intrinsic to membrane - GO:0035272//exocrine system development 41550 2616.88 343.04 350.495 0.0310170526523796 Up 0.115704662528068 Vha55 vacuolar H[+]-ATPase 55kD subunit, isoform C K02147|1|0.0|973|dmo:Dmoj_GI24752|V-type H+-transporting ATPase subunit B [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005768//endosome GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport 40008 3755.00 0.495 0.3 -0.722466024471091 Down 0.140007924976885 CG13699 CG13699 - - - - 36033 2057.85 37.745 32.8 -0.202589731502696 Down 0.379540351340642 Pal1 Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 1, isoform D K00504|1|1e-87|325|ame:408568|peptidylglycine monooxygenase [EC:1.14.17.3] GO:0044297//cell body;GO:0044297//cell body GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0016842;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0016842 GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process 33209 4339.26 15.02 7.595 -0.983762943012188 Down 0.634229295997887 CG4213 CG4213, isoform B - - - - 43423 3224.00 12.87 13.55 0.074280798020532 Up 0.143409060890239 CG1951 CG1951 K08876|1|2e-23|111|api:100161775|SCY1-like - GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process 3772054 549.00 0.225 0.01 -4.49185309632967 Down 0.222989037115308 CG33775 CG33775 K09255|1|3e-12|71.2|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|3e-10|64.3|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 37088 2676.00 1.115 1.365 0.291857240999548 Up 0.134229295997887 CG33958 CG33958 K01769|1|2e-71|270|tca:657050|guanylate cyclase, other [EC:4.6.1.2];K12323|2|1e-70|268|bta:533048|atrial natriuretic peptide receptor A [EC:4.6.1.2] - - - 32045 2357.00 165.86 183.055 0.142311182787655 Up 0.334235900145291 Hsp60 heat shock protein 60, isoform B K04077|1|0.0|1004|dme:Dmel_CG12101|chaperonin GroEL GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding;GO:0032559 GO:0006457//protein folding;GO:0006605//protein targeting;GO:0006950//response to stress;GO:0006457//protein folding;GO:0006605//protein targeting;GO:0006950//response to stress 43261 1072.00 163.445 81.365 -1.00632500103606 Down 0.731805573900409 CG14259 CG14259 - - - - 33987 1245.00 11.45 9.9 -0.209847168017334 Down 0.293224144762911 CG3476 CG3476 K03454|1|2e-131|468|dpo:Dpse_GA17470|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0022891//substrate-specific transmembrane transporter activity;GO:0015300 GO:0046907//intracellular transport;GO:0051181//cofactor transport;GO:0006865//amino acid transport 43328 1894.00 7.915 1.875 -2.07769875475394 Down 0.672104081363096 CG12880 CG12880 - - - - 3355174 2233.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 Ory Occludin-Related Y K10352|1|8e-13|75.5|dre:58142|myosin heavy chain - - - 38082 2329.00 13.75 13.625 -0.0131753887477332 Down 0.0563994188350284 ebd1 earthbound 1 - GO:0044427//chromosomal part GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression 42103 7883.35 8.125 12.58 0.63069220407611 Up 0.542200501915203 Dscam3 down syndrome cell adhesion molecule 3, isoform F K06767|1|0.0|823|rno:171119|Down syndrome cell adhesion molecule - - - 53439 1659.00 10.355 10.555 0.0275990251266439 Up 0.0763109232598072 pont pontin K04499|1|0.0|855|dme:Dmel_CG4003|RuvB-like protein 1 (pontin 52) GO:0035097//histone methyltransferase complex;GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity;GO:0004386//helicase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0006325//chromatin organization;GO:0035466;GO:0008283//cell proliferation 37070 3314.42 367.13 311.01 -0.239330040451671 Down 0.47335226522256 pAbp pAbp, isoform C K13126|1|0.0|720|nvi:100113726|polyadenylate-binding protein 1 - - - 40083 1750.84 12.89 8.675 -0.571316600896028 Down 0.527407211728966 MESR6 misexpression suppressor of ras 6, isoform B - - GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0043169//cation binding - 37929 2748.34 117.295 86.31 -0.442541889192438 Down 0.609331660282658 pio piopio, isoform E - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - GO:0007591//molting cycle, chitin-based cuticle;GO:0040003//chitin-based cuticle development;GO:0060541//respiratory system development;GO:0007591//molting cycle, chitin-based cuticle;GO:0040003//chitin-based cuticle development;GO:0060541//respiratory system development;GO:0007591//molting cycle, chitin-based cuticle;GO:0040003//chitin-based cuticle development;GO:0060541//respiratory system development 41309 1392.05 120.515 126.765 0.0729437463950411 Up 0.196572447497028 SelR selenoprotein R, isoform J K00391|1|1e-89|330|dme:Dmel_CG6584| [EC:1.8.4.-];K07305|2|2e-30|134|bmy:Bm1_44650|peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] - GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor GO:0018193//peptidyl-amino acid modification;GO:0018193//peptidyl-amino acid modification;GO:0018193//peptidyl-amino acid modification;GO:0018193//peptidyl-amino acid modification;GO:0018193//peptidyl-amino acid modification;GO:0018193//peptidyl-amino acid modification;GO:0018193//peptidyl-amino acid modification 7354476 691.00 23.205 25.765 0.150976894982837 Up 0.294677057191917 CG42371 CG42371 - - - - 38285 3503.00 0.07 0.1 0.514573172829758 Up 0.0619138819178444 CG32301 CG32301, isoform D K01768|1|0.0|2009|dme:Dmel_CG32301|adenylate cyclase [EC:4.6.1.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity;GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process 41379 1134.45 13.435 11.105 -0.274786928466185 Down 0.367256637168142 PGRP-LB peptidoglycan recognition protein LB, isoform F K01446|1|4e-128|457|dme:Dmel_CG14704|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0042742//defense response to bacterium;GO:0002376//immune system process;GO:0009581//detection of external stimulus;GO:0000270//peptidoglycan metabolic process;GO:0042742//defense response to bacterium;GO:0002376//immune system process;GO:0009581//detection of external stimulus;GO:0000270//peptidoglycan metabolic process;GO:0042742//defense response to bacterium;GO:0002376//immune system process;GO:0009581//detection of external stimulus 8673966 670.00 0.775 0.865 0.158503822362487 Up 0.0773675868445384 Skadu skadu - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0005488//binding GO:0006325//chromatin organization 19834989 860.00 0.205 0.16 -0.357552004618084 Down 0.0729097873464536 19835878 1200.00 0.01 0.115 3.52356195605701 Up 0.142748646149782 2768679 1184.00 0.695 0.935 0.427953387164129 Up 0.141725003302074 p38c p38c MAP kinase K04441|1|0.0|733|dme:Dmel_CG33338|p38 MAP kinase [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle GO:0004707//MAP kinase activity;GO:0032559 GO:0002759//regulation of antimicrobial humoral response;GO:0007243//intracellular protein kinase cascade;GO:0002251;GO:0006950//response to stress;GO:0006464//cellular protein modification process 40491 1796.00 8.22 8.585 0.0626797403204512 Up 0.110619469026549 CG11367 CG11367 - GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part GO:0043565//sequence-specific DNA binding GO:0006355//regulation of transcription, DNA-dependent;GO:0060147//regulation of posttranscriptional gene silencing;GO:0007292//female gamete generation;GO:0022403;GO:0019827//stem cell maintenance;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process 318949 823.00 1.71 2.49 0.542149417182183 Up 0.274369303922864 CG31802 CG31802 K10840|1|1e-48|192|gga:422303|centrin-2 GO:0005815//microtubule organizing center GO:0046872//metal ion binding;GO:0042623//ATPase activity, coupled;GO:0032559 - 8673976 651.00 3.67 0.825 -2.1533140385974 Down 0.571159688284242 CG42397 CG42397 K01873|1|2e-11|68.6|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K01183|5|1e-08|59.3|dme:Dmel_CG18140|chitinase [EC:3.2.1.14] - - - 19835093 559.00 1.93 5.11 1.40472244366954 Up 0.56174877823273 14462462 594.00 1.075 0.97 -0.148280007402333 Down 0.0795799762250693 35099 4231.00 7.55 7.095 -0.0896739601518895 Down 0.133932109364681 ncm nucampholin K13100|1|0.0|1043|dme:Dmel_CG12750|pre-mRNA-splicing factor CWC22 - GO:0005488//binding GO:0006909//phagocytosis;GO:0044260 41727 1713.00 65.655 55.27 -0.248408272146042 Down 0.455719191652358 CG9649 CG9649 K01362|1|1e-26|121|dpo:Dpse_GA13461| [EC:3.4.21.-];K01316|3|3e-26|120|mmu:19146|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - - - 32368 730.00 9.195 7.615 -0.272005537924645 Down 0.320697397965923 CG11590 CG11590 K03926|1|6e-88|323|dme:Dmel_CG11590|periplasmic divalent cation tolerance protein - - GO:0010035//response to inorganic substance 38047 1902.58 260.955 320.655 0.297220858589229 Up 0.534044379870559 miple miple, isoform C - - GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding - 38195 2587.00 143.07 172.885 0.273091513471511 Up 0.497523444723286 CG13928 CG13928 - - GO:0046914//transition metal ion binding - 33488 3024.70 52.155 52.145 -0.00027664334521768 Down 0.0401862369568089 CG2991 CG2991, isoform C K03871|1|3e-166|585|tca:657278|von Hippel-Lindau disease tumor supressor;K10658|2|1e-08|62.4|gga:768965|E3 ubiquitin-protein ligase MARCH3 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 33595 542.00 8.34 7.88 -0.0818517539882875 Down 0.130894201558579 CG2816 CG2816 K06238|1|2e-08|58.2|oaa:100083924|collagen, type VI, alpha;K03909|5|1e-07|55.5|mmu:21788|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 318746 1014.00 1.14 2.8 1.29639300278022 Up 0.448388588033285 CG31459 CG31459 - - - - 38684 833.00 0.01 1.525 7.25266543245025 Up 0.598302734117026 Jon65Aii jonah 65Aii K01310|1|3e-72|271|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|1e-66|253|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38375 2779.00 16.63 14.31 -0.216764496560601 Down 0.340344736494519 CG12082 CG12082, isoform B K11836|1|0.0|1630|dme:Dmel_CG12082|ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.1.2.15] - GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding GO:0019941//modification-dependent protein catabolic process 14462783 812.68 3.35 5.53 0.723118384889572 Up 0.452879408268393 CG43816 CG43816, isoform B - - - - 41578 2906.01 12.465 13.245 0.0875649608781216 Up 0.166259410910052 beat-Va beat-Va, isoform C - - - - 32071 3655.58 29.37 31.835 0.116270498558986 Up 0.258849557522124 Kap3 kinesin associated protein 3, isoform N - GO:0005871//kinesin complex;GO:0005871//kinesin complex;GO:0005871//kinesin complex;GO:0005871//kinesin complex GO:0008092//cytoskeletal protein binding;GO:0003774//motor activity;GO:0008092//cytoskeletal protein binding;GO:0003774//motor activity;GO:0008092//cytoskeletal protein binding;GO:0003774//motor activity;GO:0008092//cytoskeletal protein binding;GO:0003774//motor activity GO:0008088//axon cargo transport;GO:0042384//cilium assembly;GO:0003006//developmental process involved in reproduction;GO:0008088//axon cargo transport;GO:0042384//cilium assembly;GO:0003006//developmental process involved in reproduction;GO:0008088//axon cargo transport;GO:0042384//cilium assembly;GO:0003006//developmental process involved in reproduction;GO:0008088//axon cargo transport;GO:0042384//cilium assembly;GO:0003006//developmental process involved in reproduction 5740241 561.00 0.01 0.955 6.57742882803575 Up 0.490126799630168 33971 1547.83 15.635 16.09 0.0413851067984057 Up 0.105204068154801 CG10158 CG10158, isoform B K12656|1|8e-11|68.6|mmu:66641|suppressor of IKK-epsilon - - - 43514 1927.00 23.115 16.335 -0.500862907797878 Down 0.561121384229296 Ice Ice K04489|1|0.0|652|dme:Dmel_CG7788|caspase invertebrate, apoptosis-related cysteine protease [EC:3.4.22.-] GO:0043234//protein complex GO:0004175//endopeptidase activity GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0010212//response to ionizing radiation;GO:0007435//salivary gland morphogenesis;GO:0051605;GO:0003006//developmental process involved in reproduction 41207 3180.00 34.695 28.91 -0.263159157880297 Down 0.437161537445516 CG9467 CG9467 K04891|1|2e-06|50.1|dre:100001681|potassium voltage-gated channel Shal-related subfamily D member 1;K04893|3|3e-06|54.7|oaa:100076092|potassium voltage-gated channel Shal-related subfamily D member 3;K04892|4|4e-06|54.3|dre:570188|potassium voltage-gated channel Shal-related subfamily D member 2 GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005267//potassium channel activity GO:0030001//metal ion transport 37578 904.09 4.74 5.675 0.259733333280018 Up 0.252476555276714 CG4269 CG4269, isoform C - - - - 32742 2647.00 3.535 3.295 -0.101431749801347 Down 0.101935015189539 CG5800 CG5800 K13179|1|5e-154|545|oaa:100078673|ATP-dependent RNA helicase DDX18 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled - 41984 1048.29 64.635 61.88 -0.0628424023825033 Down 0.171773873992868 CG10311 CG10311, isoform B - - - - 32266 1464.00 0.055 0.12 1.12553088208386 Up 0.0856557918372738 CG4318 CG4318 K09228|1|2e-21|103|mmu:69930|KRAB domain-containing zinc finger protein - GO:0046914//transition metal ion binding - 246631 1791.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 Ir52b ionotropic receptor 52b - - - - 318633 386.48 21.015 28.77 0.453145764587313 Up 0.557423061682737 CG31226 CG31226, isoform B - - - - 37599 616.06 80.14 186.705 1.22016614888316 Up 0.74815083872672 CG4250 CG4250, isoform B - - - - 36680 1585.00 2.795 2.055 -0.443709889161507 Down 0.257957997622507 CG7544 CG7544, isoform B K11393|1|9e-173|606|dme:Dmel_CG7544|methyltransferase [EC:2.1.1.-] - GO:0005488//binding;GO:0016741;GO:0005488//binding;GO:0016741 GO:0006730//one-carbon metabolic process;GO:0006730//one-carbon metabolic process 37093 788.00 2.77 1.11 -1.31932629969908 Down 0.449907541936336 CG18536 CG18536 - - - - 3885594 589.00 0.08 0.34 2.08746284125034 Up 0.192576938317263 CG33998 CG33998 - - - - 19835486 551.00 0.99 2.61 1.39854937649027 Up 0.447728173292828 317908 826.00 11.455 6.39 -0.842089622357681 Down 0.583542464667811 CG32196 CG32196, isoform C K00682|1|4e-26|118|bta:533374|gamma-glutamylcyclotransferase [EC:2.3.2.4] - - - 32408 3231.14 13.76 13.32 -0.0468863876308357 Down 0.111742174085326 CG14411 CG14411, isoform D K01104|1|1e-34|149|oaa:100081312|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 35546 4756.48 8.475 6.29 -0.430153351144417 Down 0.411405362567693 Ptr Patched-related, isoform E K12385|1|7e-47|190|tad:TRIADDRAFT_28666|Niemann-Pick C1 protein GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity - 34277 1911.00 0.3 0.41 0.450661409009565 Up 0.0996896050719852 gcm glial cells missing, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007411//axon guidance;GO:0002682//regulation of immune system process;GO:0010468//regulation of gene expression;GO:0042688//crystal cell differentiation;GO:0035163//embryonic hemocyte differentiation;GO:0021782//glial cell development;GO:0006351//transcription, DNA-dependent;GO:0035168//larval lymph gland hemocyte differentiation;GO:0006950//response to stress 38923 1040.00 1.15 2.605 1.17964951133413 Up 0.418868049134857 eIF4E-3 eukaryotic translation initiation factor 4E-3 K03259|1|7e-146|516|dme:Dmel_CG8023|translation initiation factor eIF-4E GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death 37922 1149.97 164.215 178.64 0.121469242085288 Up 0.297681944260996 Nurf-38 nucleosome remodeling factor - 38kD, isoform C K01507|1|3e-172|604|dsi:Dsim_GD24942|inorganic pyrophosphatase [EC:3.6.1.1];K11726|3|3e-172|604|dme:Dmel_CG4634|nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1] GO:0031010;GO:0031010 GO:0046872//metal ion binding;GO:0016462//pyrophosphatase activity;GO:0046872//metal ion binding;GO:0016462//pyrophosphatase activity GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006793//phosphorus metabolic process;GO:0034728//nucleosome organization;GO:0010467//gene expression;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006793//phosphorus metabolic process;GO:0034728//nucleosome organization;GO:0010467//gene expression 3355064 1815.00 16.975 20.015 0.237670041255444 Up 0.3767335886937 Haspin haspin K08253|1|0.0|1145|dme:Dmel_CG40080|non-specific protein-tyrosine kinase [EC:2.7.10.2];K08286|2|9e-74|278|gga:427834|protein-serine/threonine kinase [EC:2.7.11.-] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 3354995 532.00 15.285 24.165 0.660802442540755 Up 0.613029982829217 CG17169 CG17169 - - - - 19835391 558.00 0.45 0.455 0.0159415438690215 Up 0.0413749834896315 3355114 1373.71 23.13 22.725 -0.0254849715547209 Down 0.0926231673490952 Spf45 Spf45, isoform C K12840|1|0.0|706|dsi:Dsim_GD17712|splicing factor 45 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006259//DNA metabolic process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006259//DNA metabolic process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006259//DNA metabolic process;GO:0000380//alternative mRNA splicing, via spliceosome 34281 813.73 341.87 317.165 -0.108214253409559 Down 0.283780213974376 Trx-2 thioredoxin-2, isoform B K03671|1|2e-54|213|dme:Dmel_CG31884|thioredoxin 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0015036//disulfide oxidoreductase activity;GO:0015036//disulfide oxidoreductase activity GO:0051234//establishment of localization;GO:0010259//multicellular organismal aging;GO:0018904;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0010259//multicellular organismal aging;GO:0018904;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis;GO:0006091//generation of precursor metabolites and energy 43543 873.84 9.005 15.61 0.793672356071633 Up 0.607350416061286 Jon99Ciii jonah 99Ciii, isoform B K01310|1|3e-129|461|dme:Dmel_CG31362|chymotrypsin [EC:3.4.21.1];K01362|2|3e-129|461|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0032501//multicellular organismal process;GO:0019538//protein metabolic process 19836033 401.00 0.22 0.595 1.43538614467065 Up 0.226456214502708 14462519 1978.00 36.71 33.235 -0.143469760541856 Down 0.298804649319773 318677 531.04 468.495 272.52 -0.781671538964892 Down 0.711563862105402 CG31313 CG31313, isoform C K01373|1|2e-12|72.0|dpe:Dper_GL22196|cathepsin F [EC:3.4.22.41] - GO:0004866//endopeptidase inhibitor activity - 31909 2443.00 0.435 0.595 0.451874267459215 Up 0.117917051908599 CG3106 CG3106, isoform B K00680|1|4e-96|352|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 43377 3540.00 21.065 23.215 0.140209365004408 Up 0.273543785497292 beat-VI beat-VI, isoform B - GO:0044464//cell part - - 5740131 8583.39 19.47 24.9 0.354892858235148 Up 0.491810857218333 CG34383 CG34383, isoform L K12489|1|1e-07|60.5|isc:IscW_ISCW017663|Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein;K06082|2|9e-06|54.3|cin:100177029|FERM, RhoGEF and pleckstrin domain protein 2 - - - 326220 1040.00 0.34 0.375 0.141355849245541 Up 0.0546823405098402 CG32488 CG32488, isoform B K01101|1|4e-64|244|der:Dere_GG22174|4-nitrophenyl phosphatase [EC:3.1.3.41] - GO:0042578//phosphoric ester hydrolase activity - 33978 1120.00 7.875 5.405 -0.542985305539991 Down 0.450039624884427 CG10399 CG10399, isoform B K01640|1|3e-169|594|dme:Dmel_CG10399|hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] GO:0031980;GO:0015630//microtubule cytoskeleton GO:0016829//lyase activity GO:0009081//branched-chain amino acid metabolic process 42857 618.45 32.065 46.455 0.534834476558026 Up 0.61550653810593 CG18428 CG18428, isoform C - - - - 14462738 3138.00 48.86 44.75 -0.126766181228275 Down 0.291639149385814 34775 2201.80 34.68 34.055 -0.026237266383119 Down 0.100184916127328 CG18507 CG18507, isoform E - - - - 40795 1463.00 22.58 22.655 0.00478400474038851 Up 0.0449742438251222 Zif Zinc-finger protein, isoform C K09228|1|2e-29|130|mmu:212281|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 41249 855.00 0.56 0.21 -1.41503749927884 Down 0.215559371285167 CG12420 CG12420 - - - - 326232 2219.88 52.535 57.15 0.121474599423548 Up 0.279124290054154 Tango5 transport and golgi organization 5, isoform F - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization;GO:0006996//organelle organization;GO:0006996//organelle organization;GO:0006996//organelle organization 38771 3264.00 14.045 14.76 0.0716360969339979 Up 0.146116761326113 CG8641 CG8641, isoform B K07843|1|2e-63|244|spu:574758|RAS, dexamethasone-induced 1 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 31414 5967.00 0.12 0.335 1.48112668973662 Up 0.162891295733721 CG2861 CG2861, isoform E - - GO:0004872//receptor activity GO:0023052//signaling 32080 5055.00 7.655 8.025 0.0680990145098775 Up 0.114614978206314 hop hopscotch K04447|1|0.0|2301|dme:Dmel_CG1594|Janus kinase 2 [EC:2.7.10.2] GO:0043232 GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0035168//larval lymph gland hemocyte differentiation;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0008360//regulation of cell shape;GO:0048859//formation of anatomical boundary;GO:0001745//compound eye morphogenesis;GO:0003382//epithelial cell morphogenesis;GO:0006955//immune response;GO:0042074//cell migration involved in gastrulation;GO:0007478//leg disc morphogenesis;GO:0007259//JAK-STAT cascade;GO:0007297//ovarian follicle cell migration;GO:0001736//establishment of planar polarity;GO:0003002//regionalization;GO:0002252;GO:0000060//protein import into nucleus, translocation;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0002682//regulation of immune system process;GO:0060541//respiratory system development;GO:0006952//defense response;GO:0007472//wing disc morphogenesis 8673955 679.00 0.24 0.655 1.44846050081629 Up 0.238112534671774 CG42592 CG42592 - - - - 12797918 2138.00 0.395 0.675 0.773034848873728 Up 0.170585127460045 32922 887.00 5.945 6.005 0.014487435959978 Up 0.0502575617487782 CG32536 CG32536 - - - GO:0006810//transport 36930 1723.24 23.665 19.23 -0.299396159398466 Down 0.448421608770308 CG15611 CG15611, isoform B K08810|1|1e-14|81.6|ptr:460643|triple functional domain protein [EC:2.7.11.-] - - - 37547 3029.80 7.6 4.81 -0.659962524560906 Down 0.482697133800026 CG5819 CG5819, isoform C K13023|1|2e-21|105|rno:303861|carboxypeptidase N regulatory subunit - GO:0005488//binding;GO:0005488//binding - 50075 813.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG14545 CG14545 - - - - 38411 2112.80 40.84 28.66 -0.510944256615656 Down 0.601406683397173 CG12016 CG12016, isoform B K10524|1|1e-14|82.0|ame:100187709|nicotinamide riboside kinase 1 [EC:2.7.1.-] GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0031227//intrinsic to endoplasmic reticulum membrane - GO:0009058//biosynthetic process;GO:0009058//biosynthetic process 5740876 1027.00 0.545 0.245 -1.15347448066172 Down 0.191784440628715 CG34452 CG34452, isoform C K00731|1|9e-40|164|cel:C38H2.2|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part GO:0016757//transferase activity, transferring glycosyl groups GO:0006486//protein glycosylation 3772282 476.00 8.57 2.66 -1.68786895861131 Down 0.654140800422665 His2A:CG33808 histone H2A K11251|1|1e-53|208|dan:Dana_GF18864|histone H2A GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 36342 2849.00 0.045 0.12 1.41503749927884 Up 0.0997556465460309 CG33012 CG33012 - - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 33324 921.51 119.225 66.44 -0.843562804319344 Down 0.705190859859992 NLaz neural lazarillo, isoform C K05128|1|7e-27|120|ame:410190|RYK receptor-like tyrosine kinase [EC:2.7.10.1];K03098|2|4e-10|65.5|aga:AgaP_AGAP002593|outer membrane lipoprotein Blc GO:0044421//extracellular region part GO:0005488//binding GO:0051234//establishment of localization;GO:0010259//multicellular organismal aging;GO:0055088//lipid homeostasis;GO:0006950//response to stress 35454 2140.00 27.755 26.65 -0.0586121601150444 Down 0.15315017831198 Tif-IA Tif-IA - - GO:0030528//transcription regulator activity GO:0022613//ribonucleoprotein complex biogenesis;GO:0006355//regulation of transcription, DNA-dependent 37166 1246.57 87.415 92.615 0.0833650118556272 Up 0.213413023378682 CG15093 CG15093, isoform E K00020|1|0.0|640|dme:Dmel_CG15093|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31];K00033|1|0.0|640|dme:Dmel_CG15093|6-phosphogluconate dehydrogenase [EC:1.1.1.44] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0000166//nucleotide binding GO:0009081//branched-chain amino acid metabolic process;GO:0006007//glucose catabolic process 32481 3584.00 0.035 0.075 1.09953567355091 Up 0.0725795799762251 CG6324 CG6324, isoform B K04574|1|7e-12|73.2|mmu:380684|neurofilament heavy polypeptide - - - 32892 812.00 0.31 0.225 -0.4623432140572 Down 0.0881323471139876 CG7406 CG7406 - - - - 41542 1650.00 3.9 3.75 -0.0565835283663676 Down 0.0767401928411042 CG12267 CG12267, isoform B K03023|1|0.0|1006|dme:Dmel_CG12267|DNA-directed RNA polymerase III subunit C3 [EC:2.7.7.6] - GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006351//transcription, DNA-dependent 35049 1587.00 0.535 2.095 1.9693394472982 Up 0.460474177783648 CG6639 CG6639 K08664|1|8e-28|125|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-];K01317|2|1e-27|124|mdo:100010132|acrosin [EC:3.4.21.10];K09630|3|1e-27|124|cfa:489924|protease, serine, 36 [EC:3.4.21.-];K01312|5|1e-27|124|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 2768955 780.00 0.105 0.075 -0.485426827170242 Down 0.0618808611808216 Obp73a Odorant-binding protein 73a - - GO:0005488//binding GO:0051234//establishment of localization 19835683 890.00 2.715 4.405 0.698189821116052 Up 0.408070268128385 8674090 676.00 0.3 0.4 0.415037499278844 Up 0.0948685774666491 CG42597 CG42597 - - - - 31173 1097.00 0.335 0.29 -0.2081081953302 Down 0.0611874257033417 CG4194 CG4194 - - - - 31259 1952.00 7.135 7.09 -0.00912780223624738 Down 0.0472856954167217 CG2685 CG2685 K12866|1|1e-113|410|dme:Dmel_CG2685|WW domain-binding protein 11 - - - 318651 921.00 0.425 0.66 0.635003183220752 Up 0.149517897239466 CG31267 CG31267 K11997|1|2e-28|126|ame:409206|tripartite motif-containing protein 2/3;K01312|2|5e-28|124|dme:Dmel_CG18681|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41330 1826.60 27.945 26.285 -0.0883504400909181 Down 0.202549200898164 CG4757 CG4757, isoform B K03927|1|1e-81|304|dse:Dsec_GM17558|carboxylesterase type B [EC:3.1.1.1] - GO:0003824//catalytic activity - 43415 4003.06 113.46 84.265 -0.429178340926268 Down 0.603387927618544 Doa darkener of apricot, isoform Z K08823|1|0.0|737|dpe:Dper_GL24199|CDC-like kinase [EC:2.7.12.1];K10750|4|1e-169|598|tca:659421|chromatin assembly factor 1 subunit A GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance;GO:0040003//chitin-based cuticle development;GO:0009880//embryonic pattern specification;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007243//intracellular protein kinase cascade;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051276//chromosome organization;GO:0048102//autophagic cell death;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0043954//cellular component maintenance 35894 897.00 2.275 0.39 -2.54432051622381 Down 0.512316734909523 CG13749 CG13749 - - - - 39874 3145.00 6.02 7.595 0.335286477742382 Up 0.345429929996037 CG13025 CG13025, isoform B K08849|1|2e-42|174|rno:361409|mixed lineage kinase domain-like [EC:2.7.11.1] - GO:0046914//transition metal ion binding - 19835466 263.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 32980 815.40 12.285 14.605 0.249564500467014 Up 0.355864482895258 CG14229 CG14229, isoform C - - - - 38584 2948.00 0.08 0.115 0.523561956057013 Up 0.0682868841632545 CG32237 CG32237 - - - - 42885 1174.10 61.915 65.18 0.0741403819905018 Up 0.190100383040549 Spase22-23 spase 22/23-subunit, isoform B K12948|1|8e-102|369|dme:Dmel_CG5677|signal peptidase complex subunit 3 [EC:3.4.-.-];K01423|3|2e-78|291|cqu:CpipJ_CPIJ016903| [EC:3.4.-.-] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane GO:0016787//hydrolase activity GO:0051605 43321 604.00 0.88 0.775 -0.18330721336306 Down 0.0812640338132347 RpS10a ribosomal protein S10a K02947|1|2e-81|300|dme:Dmel_CG12275|small subunit ribosomal protein S10e GO:0015630//microtubule cytoskeleton;GO:0015935//small ribosomal subunit - - 319019 1470.00 1.875 2.01 0.100304905795685 Up 0.0794478932769779 CG31907 CG31907, isoform B K10436|1|6e-19|95.5|dmo:Dmoj_GI16249|microtubule-associated protein, RP/EB family GO:0005874//microtubule - GO:0000278//mitotic cell cycle;GO:0032501//multicellular organismal process;GO:0007051//spindle organization 33855 1366.15 10.66 15.11 0.503296222405653 Up 0.518788799366002 CG9147 CG9147, isoform D K00626|1|2e-29|130|cqu:CpipJ_CPIJ019232|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] - GO:0016746//transferase activity, transferring acyl groups;GO:0016746//transferase activity, transferring acyl groups - 34161 2377.00 1.025 1.365 0.413277041414407 Up 0.170023774930656 CG42820 CG42820 - - - - 32799 3849.30 23.96 37.965 0.664042100043055 Up 0.639413551710474 Frq2 frequenin 2, isoform D K13764|1|9e-42|172|cfa:489500|recoverin GO:0044297//cell body;GO:0030136//clathrin-coated vesicle;GO:0044297//cell body;GO:0030136//clathrin-coated vesicle;GO:0044297//cell body;GO:0030136//clathrin-coated vesicle GO:0030250//guanylate cyclase activator activity;GO:0046872//metal ion binding;GO:0030250//guanylate cyclase activator activity;GO:0046872//metal ion binding;GO:0030250//guanylate cyclase activator activity;GO:0046872//metal ion binding GO:0006810//transport;GO:0048741//skeletal muscle fiber development;GO:0050804//regulation of synaptic transmission;GO:0006810//transport;GO:0048741//skeletal muscle fiber development;GO:0050804//regulation of synaptic transmission;GO:0006810//transport;GO:0048741//skeletal muscle fiber development;GO:0050804//regulation of synaptic transmission 35980 1191.00 1.96 2.795 0.511994628727982 Up 0.281369700171708 Or45b odorant receptor 45b K08471|1|0.0|780|dme:Dmel_CG12931|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0007166//cell surface receptor signaling pathway;GO:0023060 37132 4655.46 12.465 16.105 0.369625777891314 Up 0.461728965790516 Rgk2 Rad, Gem/Kir family member 2, isoform C K07847|1|0.0|1216|dme:Dmel_CG34390|Rad and Gem related GTP binding protein 1 - - - 36309 1124.00 7.01 6.9 -0.0228180823450916 Down 0.0598335754854048 EndoG endonuclease G K01173|1|2e-170|598|dme:Dmel_CG8862|endonuclease [EC:3.1.30.-] GO:0043231//intracellular membrane-bounded organelle GO:0004519//endonuclease activity;GO:0043169//cation binding GO:0006260//DNA replication 36257 1686.00 0.135 0.155 0.199308808223407 Up 0.0514463082816008 Tango3 ionotropic receptor 48c - - - GO:0006996//organelle organization 19834907 614.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 - CG44477 - - - - 32546 3852.31 29.635 34.395 0.214896798134337 Up 0.385847312112006 CG16952 CG16952, isoform E K10479|1|0.0|919|dpo:Dpse_GA14232|BTB/POZ domain-containing protein 7 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 37255 384.00 12.075 7.37 -0.712286664628066 Down 0.559932637696473 CG18367 CG18367 - - - - 318736 680.00 0.475 0.42 -0.177538185552187 Down 0.0649848104609695 CheB93b chemosensory protein B 93b - - - GO:0009593//detection of chemical stimulus 117338 1305.00 0.07 0.185 1.40209844357135 Up 0.120525690133404 Gr97a gustatory receptor 97a, isoform B K08471|1|7e-08|58.5|dme:Dmel_CG13417|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38961 4168.46 15.785 20.56 0.381286003880893 Up 0.492504292695813 Cbl Cbl, isoform B K04707|1|0.0|902|dya:Dyak_GE20742|E3 ubiquitin-protein ligase CBL [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0060089;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0060089;GO:0003824//catalytic activity GO:0001752//compound eye photoreceptor fate commitment;GO:0008283//cell proliferation;GO:0007297//ovarian follicle cell migration;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007472//wing disc morphogenesis;GO:0019538//protein metabolic process;GO:0001752//compound eye photoreceptor fate commitment;GO:0008283//cell proliferation;GO:0007297//ovarian follicle cell migration;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007472//wing disc morphogenesis;GO:0019538//protein metabolic process 39663 7182.64 7.255 8.595 0.244522025411317 Up 0.290219257693832 Toll-6 Toll-6, isoform C K05401|1|7e-44|180|dme:Dmel_CG5195|toll-like recepto 3;K06839|5|7e-44|180|dre:80353|slit 2 GO:0031224//intrinsic to membrane GO:0004872//receptor activity;GO:0005488//binding GO:0006952//defense response;GO:0023060 31355 3046.05 8.985 10.005 0.155130758395799 Up 0.228536520935147 CG6379 CG6379, isoform B K02427|1|4e-09|64.3|spu:593523|ribosomal RNA large subunit methyltransferase E [EC:2.1.1.-] GO:0044464//cell part GO:0005488//binding;GO:0016741 GO:0006730//one-carbon metabolic process 34307 1965.00 1.145 1.355 0.242945253256928 Up 0.115935807687228 CG5924 mitochondrial DNA helicase - GO:0005759//mitochondrial matrix GO:0003678//DNA helicase activity;GO:0032559;GO:0043566//structure-specific DNA binding GO:0051259//protein oligomerization;GO:0006261//DNA-dependent DNA replication;GO:0007005//mitochondrion organization 53563 5408.97 6.045 6.5 0.104697378666693 Up 0.140106987187954 gukh GUK-holder, isoform E K06220|1|3e-11|71.6|dpe:Dper_GL19132|WAS protein family GO:0033267//axon part;GO:0033267//axon part;GO:0033267//axon part;GO:0033267//axon part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006935//chemotaxis;GO:0033036;GO:0006935//chemotaxis;GO:0033036;GO:0006935//chemotaxis;GO:0033036;GO:0006935//chemotaxis;GO:0033036 14462561 1199.00 2.845 3.025 0.0885064898553749 Up 0.088033284902919 31775 3145.85 8.89 11.025 0.310523331615113 Up 0.376238277638357 CG12125 CG12125, isoform C - - - - 32177 472.00 0.355 0.69 0.958777337273487 Up 0.198388588033285 CG15734 CG15734, isoform D - - - - 36122 2503.00 11.475 10.185 -0.172048173335282 Down 0.256967375511821 Git G protein-coupled receptor kinase interacting ArfGAP K12487|1|3e-113|409|mmu:26431|G protein-coupled receptor kinase interactor 2 GO:0044424//intracellular part GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding GO:0032012//regulation of ARF protein signal transduction;GO:0061061//muscle structure development 250811 3198.48 9.455 10.805 0.192549708909746 Up 0.271034209483556 bru-2 bruno-2, isoform M K13207|1|8e-171|601|dvi:Dvir_GJ17718|CUG-BP- and ETR3-like factor - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 3772105 3037.64 1.78 3.285 0.884016129355932 Up 0.404933298111214 CG9130 CG9130, isoform B - - - - 53425 9093.30 24.5 25.12 0.0360547150016942 Up 0.1132941487254 Alk Alk, isoform B K05119|1|0.0|3089|dme:Dmel_CG8250|anaplastic lymphoma kinase [EC:2.7.10.1] GO:0016021//integral to membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0009888//tissue development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007517//muscle organ development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0002682//regulation of immune system process;GO:0000165//MAPK cascade 34425 1623.00 47.14 43.385 -0.11975542942478 Down 0.273940034341566 CG5168 CG5168, isoform B K03130|1|1e-11|71.2|bfo:BRAFLDRAFT_65485|transcription initiation factor TFIID subunit D4;K12182|2|3e-10|67.0|xtr:549267|hepatocyte growth factor-regulated tyrosine kinase substrate - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 35857 1970.23 0.43 0.87 1.01667874114663 Up 0.231673490952318 CG12376 CG12376, isoform B K13754|1|0.0|644|dwi:Dwil_GK21735|solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 GO:0031224//intrinsic to membrane - GO:0006810//transport 33607 1425.00 8.58 9.67 0.172538241977296 Up 0.240291903315282 slp1 sloppy paired 1 K09385|1|4e-50|199|tca:662507|forkhead box protein G GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0007380//specification of segmental identity, head;GO:0006351//transcription, DNA-dependent;GO:0048645//organ formation;GO:0000578//embryonic axis specification;GO:0001704//formation of primary germ layer 35483 11515.00 8.65 10.94 0.33884070026847 Up 0.39631488574825 Nipped-A Nipped-A, isoform E K08874|1|0.0|6905|dme:Dmel_CG33554|transformation/transcription domain-associated protein GO:0070461//SAGA-type complex;GO:0015630//microtubule cytoskeleton;GO:0005700//polytene chromosome;GO:0070461//SAGA-type complex;GO:0015630//microtubule cytoskeleton;GO:0005700//polytene chromosome GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0007447//imaginal disc pattern formation;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0008593//regulation of Notch signaling pathway;GO:0051301//cell division;GO:0007447//imaginal disc pattern formation;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0008593//regulation of Notch signaling pathway;GO:0051301//cell division 3771944 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 12798456 918.00 0.085 0.05 -0.765534746362977 Down 0.0626403381323471 38735 3885.00 5.745 6.15 0.098279517580489 Up 0.133139611676133 CG10144 CG10144 - - GO:0046914//transition metal ion binding - 43330 2892.00 52.925 48.13 -0.137012940930079 Down 0.309800554748382 ALiX ALG-2 interacting protein X K12200|1|0.0|1406|dme:Dmel_CG12876|programmed cell death 6-interacting protein - - GO:0012501//programmed cell death;GO:0043410//positive regulation of MAPK cascade;GO:0008154//actin polymerization or depolymerization 19835739 438.00 0.1 0.11 0.137503523749935 Up 0.0448421608770308 34770 751.00 0.735 1.88 1.35491650684127 Up 0.386606789063532 CG9263 CG9263 - - - - 42253 5382.56 9.555 12.28 0.361982782392723 Up 0.424910844010038 Mekk1 Mekk1, isoform D K11230|1|0.0|1351|aag:AaeL_AAEL010466|mitogen-activated protein kinase kinase kinase [EC:2.7.11.25];K04428|2|6e-119|429|rno:308106|mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25] - GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559 GO:0002251;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007243//intracellular protein kinase cascade;GO:0002251;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0007243//intracellular protein kinase cascade 38500 2100.00 17.555 17.165 -0.0324121389234984 Down 0.0922599392418439 Ero1L endoplasmic reticulum oxidoreductin-1-like K10950|1|2e-115|416|tgu:100222902|ERO1-like protein alpha [EC:1.8.4.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0030554//adenyl nucleotide binding;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors GO:0051084//'de novo' posttranslational protein folding 39714 1681.00 0.275 0.01 -4.78135971352466 Down 0.252509576013737 CG7579 CG7579 K00710|1|0.0|1019|dme:Dmel_CG7579|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process 19834722 986.00 0.275 0.09 -1.61143471208235 Down 0.152423722097477 45325 3654.00 5.225 4.96 -0.0750909165813698 Down 0.101043455289922 lin lines - GO:0043231//intracellular membrane-bounded organelle - GO:0007444//imaginal disc development;GO:0009653//anatomical structure morphogenesis;GO:0009888//tissue development;GO:0008152//metabolic process;GO:0009798//axis specification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 50454 641.00 0.44 0.49 0.155278225477911 Up 0.0640932505613525 CG15283 CG15283 - - - - 31026 3612.79 9.79 9.255 -0.0810758697331207 Down 0.138125742966583 CG16989 CG16989, isoform B - - - - 318134 642.00 0.065 0.28 2.10691520391651 Up 0.175934486857747 CG32639 CG32639 - - - - 40381 1827.00 23.67 10.865 -1.12337153155333 Down 0.684453837009642 Est-Q esterase Q K03927|1|5e-54|212|dmo:Dmoj_GI23478|carboxylesterase type B [EC:3.1.1.1];K01050|4|3e-51|203|dpo:Dpse_GA10907|cholinesterase [EC:3.1.1.8];K01044|5|3e-50|199|dpo:Dpse_GA10768|carboxylesterase [EC:3.1.1.1] - GO:0003824//catalytic activity - 53543 974.00 0.6 0.28 -1.09953567355091 Down 0.197133800026417 lectin-24A lectin-24A K10068|1|1e-09|63.9|mmu:20390|surfactant, pulmonary-associated protein D;K10065|4|2e-08|59.7|gga:420281|collectin sub-family member 10 - GO:0005488//binding - 44087 2527.00 7.08 6.68 -0.0839012576089453 Down 0.123464535728437 Rs1 Rs1, isoform B K13181|1|0.0|1179|dme:Dmel_CG2173|ATP-dependent RNA helicase DDX27 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity GO:0022613//ribonucleoprotein complex biogenesis 36627 1791.00 0.55 0.87 0.661583782324069 Up 0.176495839387135 Adgf-E adenosine deaminase-related growth factor E K01488|1|0.0|1056|dme:Dmel_CG10143|adenosine deaminase [EC:3.5.4.4] GO:0044421//extracellular region part GO:0005102//receptor binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0009127//purine nucleoside monophosphate biosynthetic process 37960 887.42 373.18 362.08 -0.0435631795537026 Down 0.138852199181086 GstE12 glutathione S transferase E12, isoform D K00799|1|1e-48|192|dme:Dmel_CG17525|glutathione S-transferase [EC:2.5.1.18] - - - 40069 1328.00 0.39 0.27 -0.53051471669878 Down 0.105105005943733 CG3819 CG3819, isoform B - - GO:0043169//cation binding;GO:0003824//catalytic activity - 32567 2619.80 82.5 81.58 -0.0161786122280172 Down 0.0877030775326905 exd extradenticle, isoform E K09355|1|4e-180|631|dsi:Dsim_GD17261|pre-B-cell leukemia transcription factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007417//central nervous system development;GO:0007423//sensory organ development;GO:0006355//regulation of transcription, DNA-dependent;GO:0006606//protein import into nucleus;GO:0001742//oenocyte differentiation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007431//salivary gland development;GO:0007417//central nervous system development;GO:0007423//sensory organ development;GO:0006355//regulation of transcription, DNA-dependent;GO:0006606//protein import into nucleus;GO:0001742//oenocyte differentiation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007431//salivary gland development 41226 1102.00 13.495 13.195 -0.0324336261405832 Down 0.0864152687887994 CG3909 CG3909 K12602|1|0.0|680|dme:Dmel_CG3909|WD repeat-containing protein 61 GO:0043231//intracellular membrane-bounded organelle GO:0004866//endopeptidase inhibitor activity - 36365 2949.00 5.16 5.21 0.0139123068552541 Up 0.0492999603751156 CG8545 CG8545 K00599|1|3e-12|74.3|dre:553534| [EC:2.1.1.-] - GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0042254//ribosome biogenesis 35197 10561.01 11.04 9.865 -0.16234921605461 Down 0.242438251221767 brat brain tumor, isoform F K11997|1|0.0|659|dya:Dyak_GE13236|tripartite motif-containing protein 2/3 GO:0044448//cell cortex part;GO:0044448//cell cortex part;GO:0044448//cell cortex part;GO:0044448//cell cortex part GO:0046914//transition metal ion binding;GO:0045182//translation regulator activity;GO:0046914//transition metal ion binding;GO:0045182//translation regulator activity;GO:0046914//transition metal ion binding;GO:0045182//translation regulator activity;GO:0046914//transition metal ion binding;GO:0045182//translation regulator activity GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0006412//translation;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0003002//regionalization;GO:0034660//ncRNA metabolic process;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007049//cell cycle;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0006412//translation;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0003002//regionalization;GO:0034660//ncRNA metabolic process;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007049//cell cycle;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0006412//translation;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0003002//regionalization;GO:0034660//ncRNA metabolic process;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007049//cell cycle;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0006412//translation;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0003002//regionalization;GO:0034660//ncRNA metabolic process;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007049//cell cycle 39014 2451.00 1.815 1.27 -0.515141051223585 Down 0.225333509443931 Mcm7 minichromosome maintenance 7 K02210|1|0.0|1345|dme:Dmel_CG4978|minichromosome maintenance protein 7 (cell division control protein 47) GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044427//chromosomal part;GO:0032993//protein-DNA complex GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0060255;GO:0006270//DNA replication initiation;GO:0010467//gene expression 33675 1992.89 0.845 1.325 0.648969113168377 Up 0.219686963413023 CG15631 CG15631, isoform B - - - - 33959 1552.00 5.88 6.135 0.0612471888265405 Up 0.0939439968300092 Rca1 regulator of cyclin A1 - GO:0043231//intracellular membrane-bounded organelle - GO:0048592//eye morphogenesis;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0051319;GO:0007067//mitosis 31516 1014.00 0.615 0.64 0.0574854946607603 Up 0.0489697530048871 CG15764 CG15764, isoform B - - - - 46260 718.43 313.285 291.425 -0.104351050687227 Down 0.263736626601506 l(3)neo18 lethal (3) neo18, isoform B K03961|1|2e-106|385|dme:Dmel_CG9762|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0010259//multicellular organismal aging;GO:0006979//response to oxidative stress;GO:0022904//respiratory electron transport chain 35985 2358.00 2.605 3.74 0.521754897609129 Up 0.325848632941487 CG1868 CG1868, isoform C K11426|1|1e-06|55.5|cfa:480101|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006350;GO:0006350 36475 3271.41 11.975 11.035 -0.117939026343928 Down 0.198256505085193 Dh31-R1 diuretic hormone 31 receptor, isoform C K04577|1|0.0|884|dme:Dmel_CG32843|calcitonin receptor-like GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 38021 2792.99 25.97 30.505 0.232199716659223 Up 0.399253731343284 p130CAS p130CAS, isoform G K05726|1|1e-41|172|xtr:447979|breast cancer anti-estrogen resistance 1 - - GO:0007409//axonogenesis;GO:0007010//cytoskeleton organization;GO:0007409//axonogenesis;GO:0007010//cytoskeleton organization;GO:0007409//axonogenesis;GO:0007010//cytoskeleton organization;GO:0007409//axonogenesis;GO:0007010//cytoskeleton organization;GO:0007409//axonogenesis;GO:0007010//cytoskeleton organization 59158 476.68 510.86 389.165 -0.392546012570209 Down 0.598963148857482 Cpr65Au cuticular protein 65Au, isoform B - - GO:0005198//structural molecule activity - 42840 2966.38 8.355 10.03 0.263609872550993 Up 0.324197596090345 CG13604 CG13604, isoform E K12470|1|2e-06|55.5|gga:418608|SH3 domain-containing kinase-binding protein 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0044260;GO:0044260;GO:0044260;GO:0044260 19836037 701.00 0.12 0.195 0.700439718141092 Up 0.0912362963941355 33359 1998.76 1.28 1.73 0.434628227636725 Up 0.198487650244353 CG31664 CG31664, isoform C - - - - 33670 1446.00 0.03 0.065 1.11547721741994 Up 0.0725795799762251 CG15634 early boundary activity 3 - - - - 40291 951.00 20.095 20.58 0.0344064048352233 Up 0.0960903447364945 CG4042 CG4042, isoform B K07554|1|2e-08|59.7|dre:393187|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s - GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity - 41800 1632.00 475.58 495.935 0.0604629999773403 Up 0.183958525954299 CG3731 CG3731, isoform B K01412|1|0.0|902|dsi:Dsim_GD18983|mitochondrial processing peptidase [EC:3.4.24.64] - - - 35617 1010.00 9.165 11.325 0.305304264393712 Up 0.377922335226522 Tsp42Eh tetraspanin 42Eh K06497|1|4e-16|85.1|dme:Dmel_CG18817|CD63 antigen;K06537|5|3e-08|59.3|hsa:977|CD151 antigen GO:0031224//intrinsic to membrane - - 38351 1631.00 0.585 0.83 0.50467471176352 Up 0.14515915995245 CG9970 CG9970 K10456|1|2e-07|57.4|hmg:100208712|kelch-like protein 19;K10471|2|5e-06|52.8|oaa:100078114|kelch repeat and BTB domain-containing protein 3 - - - 36847 2026.71 12.435 20.81 0.742870457518428 Up 0.622870162462026 loopin-1 loopin-1, isoform C K01255|1|0.0|1009|dme:Dmel_CG4750|leucyl aminopeptidase [EC:3.4.11.1] - - - 14462863 416.00 2.92 1.945 -0.586198213893825 Down 0.307852331264034 39334 11198.00 0.04 0.03 -0.415037499278844 Down 0.0473847576277902 CG42255 CG42255 K02599|1|5e-52|208|dse:Dsec_GM19264|Notch - GO:0046872//metal ion binding;GO:0016453;GO:0048037//cofactor binding GO:0008152//metabolic process 37008 482.00 7.17 5.055 -0.50426202679889 Down 0.419627526086382 CG42562 CG42562 - - - - 117475 1194.00 0.04 0.04 0 - 0.0382380134724607 Gr85a gustatory receptor 85a K08471|1|0.0|787|dme:Dmel_CG31405|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 318905 1727.00 0.09 0.205 1.18762700317577 Up 0.118445383700964 CG31703 CG31703 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0006464//cellular protein modification process 31255 2039.75 7.515 7.105 -0.0809384546735843 Down 0.124686302998283 Csat csat, isoform C - - - - 35835 2959.00 16.915 11.18 -0.597382988950798 Down 0.566569805838066 Cyp6a14 Cyp6a14, isoform E - - - - 19835582 645.00 0.755 1.5 0.990413951170802 Up 0.298045172368247 246659 686.00 0.175 0.2 0.192645077942396 Up 0.0514463082816008 CheA29a chemosensory protein A 29a - - - - 37629 2295.03 321.73 510.885 0.667148110011918 Up 0.690430590410778 inaD inactivation no afterpotential D, isoform B K13804|1|0.0|1169|dme:Dmel_CG3504|inactivation no afterpotential D protein GO:0016020//membrane;GO:0016028//rhabdomere GO:0032947//protein complex scaffold;GO:0017022//myosin binding GO:0009583//detection of light stimulus;GO:0033036;GO:0007165//signal transduction 43639 1734.00 2.7 3.865 0.517509006874017 Up 0.330372473913618 CG2267 CG2267, isoform B - - - - 246490 844.00 1.845 1.445 -0.352551323559718 Down 0.180293224144763 CG30160 CG30160 K06497|1|2e-128|457|dme:Dmel_CG30160|CD63 antigen GO:0031224//intrinsic to membrane - - 326187 2187.24 6.32 10.79 0.771698401310914 Up 0.562244089288073 S-Lap3 Sperm-Leucylaminopeptidase 3, isoform D K01255|1|0.0|1001|dme:Dmel_CG32063|leucyl aminopeptidase [EC:3.4.11.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 31149 8251.00 4.725 5.87 0.313046174001617 Up 0.295139347510236 trr trithorax-related, isoform D K09188|1|0.0|3710|dme:Dmel_CG3848|myeloid/lymphoid or mixed-lineage leukemia protein 3 - - - 36588 3673.21 11.125 5.17 -1.10556915042619 Down 0.624950468894466 conv convoluted, isoform B K05401|1|7e-52|206|dme:Dmel_CG5195|toll-like recepto 3 - GO:0005488//binding GO:0035151//regulation of tube size, open tracheal system;GO:0007411//axon guidance 19835612 1740.00 0.34 0.2 -0.765534746362977 Down 0.118544445912033 318605 961.00 0.57 1.17 1.03747470541866 Up 0.272751287808744 CG31141 CG31141 K00680|1|1e-53|209|dme:Dmel_CG8534| [EC:2.3.1.-];K10249|4|7e-28|124|spu:593296|elongation of very long chain fatty acids protein 4 GO:0031224//intrinsic to membrane - - 36056 3638.77 224.475 274.965 0.292693211662022 Up 0.522652225597675 CG2269 CG2269, isoform D - - - - 31448 3223.87 12.185 12.89 0.0811460126383104 Up 0.153447364945186 Rnp4F RNA-binding protein 4F, isoform F K12890|1|1e-06|55.8|nve:NEMVE_v1g202761|splicing factor, arginine/serine-rich 1/9;K13091|2|2e-06|55.5|dya:Dyak_GE14328|RNA-binding protein 39 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0010467//gene expression;GO:0007399//nervous system development;GO:0010467//gene expression;GO:0007399//nervous system development;GO:0010467//gene expression;GO:0007399//nervous system development;GO:0010467//gene expression;GO:0007399//nervous system development 32909 3024.74 52.32 61.17 0.22546173523967 Up 0.432142385418043 CG7990 CG7990, isoform D - - - - 31849 1513.00 30.455 30.425 -0.00142184148258514 Down 0.0427618544445912 Ost48 oligosaccharyltransferase 48kD subunit K12670|1|0.0|876|dme:Dmel_CG9022|oligosaccharyltransferase complex subunit beta GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0004576//oligosaccharyl transferase activity GO:0006487//protein N-linked glycosylation 5740254 738.00 192.425 27.555 -2.80391021502121 Down 0.814456478668604 CG34217 CG34217 - - - - 33419 4059.51 10.37 11.025 0.0883627616316572 Up 0.155527671377625 Axud1 Axud1, isoform D - - - - 44097 8540.41 8.66 10.705 0.305845865658785 Up 0.370558710870427 sns sticks and stones, isoform C K12567|1|1e-36|157|dre:317731|titin [EC:2.7.11.1] GO:0016020//membrane;GO:0016020//membrane - GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0016337//cell-cell adhesion;GO:0002164//larval development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0016337//cell-cell adhesion;GO:0002164//larval development;GO:0000768//syncytium formation by plasma membrane fusion 14462759 314.00 0.435 0.01 -5.44294349584873 Down 0.334599128252543 CG43925 CG43925 - - - - 31965 2488.00 120.96 102.86 -0.233847985868616 Down 0.450667018887862 CG17841 CG17841 - GO:0031224//intrinsic to membrane - - 8674000 1845.11 40.195 38.8 -0.0509593981499888 Down 0.143607185312376 CG42542 CG42542, isoform G - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - - 40411 2980.96 12.545 15.29 0.285475935951632 Up 0.396876238277638 CG11248 CG11248, isoform C K10352|1|6e-20|100|dwi:Dwil_GK20720|myosin heavy chain - - - 41368 1990.00 37.02 19.09 -0.955487792466636 Down 0.688152159556201 CG6723 CG6723 K03307|1|0.0|1112|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport 43215 3991.00 82.4 94.585 0.198967070876333 Up 0.410414740457007 amon amontillado K01360|1|0.0|1294|dme:Dmel_CG6438|proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94] - GO:0004175//endopeptidase activity GO:0009791//post-embryonic development;GO:0051605;GO:0007610//behavior 32034 2134.44 4.495 5.85 0.380115508956319 Up 0.333245278034606 CG11160 CG11160, isoform C K11848|1|2e-12|75.1|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15];K11426|2|1e-09|65.9|cin:778761|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0006350;GO:0006350 43982 3753.43 17.775 19.65 0.144679752639191 Up 0.265123497556465 Oamb octopamine receptor in mushroom bodies, isoform F K04165|1|0.0|1187|dsi:Dsim_GD20042|Octopamine receptor GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0008227//G-protein coupled amine receptor activity;GO:0008227//G-protein coupled amine receptor activity;GO:0008227//G-protein coupled amine receptor activity GO:0007292//female gamete generation;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007292//female gamete generation;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007292//female gamete generation;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 42482 1674.00 0.12 0.28 1.22239242133645 Up 0.137993660018492 CG10827 CG10827 K01077|1|0.0|1044|dme:Dmel_CG10827|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 42462 1331.67 17.325 19.83 0.194829325204272 Up 0.327664773477744 CG17270 CG17270, isoform B - GO:0031224//intrinsic to membrane - - 38015 2501.00 0.76 1.055 0.4731716752636 Up 0.159655263505481 Lsp1gamma larval serum protein 1 gamma K00505|1|6e-36|152|dya:Dyak_GE14257|tyrosinase [EC:1.14.18.1] GO:0044444//cytoplasmic part;GO:0044421//extracellular region part GO:0022892 GO:0051234//establishment of localization 41189 3376.00 2.715 3.035 0.160744318451321 Up 0.133634922731475 CG16908 CG16908 - - - - 32672 2910.87 30.28 28.705 -0.0770631497144616 Down 0.187854972922996 CG4829 CG4829, isoform F K00681|1|6e-126|452|aga:AgaP_AGAP000853|gamma-glutamyltranspeptidase [EC:2.3.2.2] - GO:0016755;GO:0016755;GO:0016755;GO:0016755;GO:0016755 - 19835909 904.00 0.52 0.245 -1.08572987402588 Down 0.183066966054682 38979 1514.00 12.695 16.625 0.389093945628408 Up 0.476654338924845 CG6638 CG6638 K00253|1|0.0|850|dme:Dmel_CG6638|isovaleryl-CoA dehydrogenase [EC:1.3.99.10] GO:0031980 GO:0030554//adenyl nucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity GO:0006551//leucine metabolic process 40965 3072.17 6.02 6.495 0.109566038688179 Up 0.146942279751684 DNApol-iota DNApol-iota, isoform C K03510|1|0.0|1204|dme:Dmel_CG7602|DNA polymerase iota subunit [EC:2.7.7.7] - GO:0003677//DNA binding;GO:0034061;GO:0003677//DNA binding;GO:0034061 GO:0006301//postreplication repair;GO:0006301//postreplication repair 14462648 552.00 2.665 1.88 -0.503402871081539 Down 0.272024831594241 39313 1622.00 15.01 13.625 -0.139667747069037 Down 0.242801479329019 TfIIEalpha transcription factor IIEalpha K03136|1|0.0|742|dme:Dmel_CG10415|transcription initiation factor TFIIE alpha subunit GO:0005667//transcription factor complex GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 40078 1201.00 8.845 12.42 0.489731125530023 Up 0.491810857218333 Acp76A accessory gland protein 76A, isoform B K13963|1|3e-12|72.8|dan:Dana_GF13146|serpin B - GO:0005488//binding;GO:0004866//endopeptidase inhibitor activity GO:0030162//regulation of proteolysis 50415 494.00 0.17 0.01 -4.08746284125034 Down 0.187062475234447 CG15308 CG15308, isoform C - - - - 8674060 279.00 0.01 0.19 4.24792751344359 Up 0.201558578787479 CG42587 CG42587 - - - - 50005 441.05 860.8 1031.95 0.261623088045125 Up 0.498547087570995 CG8369 CG8369, isoform C - - - GO:0051234//establishment of localization 41902 1171.00 0.56 1.06 0.920565532505595 Up 0.24247127195879 CG4520 CG4520, isoform B K11518|1|5e-19|95.5|nvi:100124015|mitochondrial import receptor subunit TOM40 - - - 34116 1559.68 9.385 11.81 0.331580314566283 Up 0.400079249768855 CG8455 Post-GPI attachment to proteins 5 ortholog, isoform C - - GO:0003824//catalytic activity;GO:0003824//catalytic activity - 31747 1235.98 47.15 35.82 -0.396492433576498 Down 0.559041077796856 GIIIspla2 GIIIspla2, isoform C K01047|1|2e-143|508|dme:Dmel_CG1583|phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 19836248 1146.00 0.04 0.01 -2 Down 0.0694426099590543 39078 1225.35 54.675 41.885 -0.384447641757396 Down 0.556003169990754 Hsp27 heat shock protein 27, isoform B K09542|1|2e-23|110|dme:Dmel_CG4533|crystallin, alpha B;K04455|2|6e-17|88.6|bta:516099|heat shock 27kDa protein 1 GO:0015630//microtubule cytoskeleton - GO:0006457//protein folding;GO:0010259//multicellular organismal aging;GO:0006950//response to stress 318161 855.00 9.85 8.83 -0.157710286695273 Down 0.228536520935147 CG32708 CG32708 - - GO:0005488//binding - 40992 616.00 0.01 0.15 3.90689059560852 Up 0.171410645885616 CG7443 CG7443, isoform B - - - - 32946 3375.68 8.86 10.07 0.184685079451766 Up 0.255547483819839 Grip84 Gamma-tubulin ring protein 84, isoform F K01769|1|1e-11|72.4|tca:657050|guanylate cyclase, other [EC:4.6.1.2] GO:0000930//gamma-tubulin complex;GO:0000930//gamma-tubulin complex;GO:0000930//gamma-tubulin complex;GO:0000930//gamma-tubulin complex;GO:0000930//gamma-tubulin complex GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding GO:0031023//microtubule organizing center organization;GO:0000087//M phase of mitotic cell cycle;GO:0007051//spindle organization;GO:0048232//male gamete generation;GO:0031023//microtubule organizing center organization;GO:0000087//M phase of mitotic cell cycle;GO:0007051//spindle organization;GO:0048232//male gamete generation;GO:0031023//microtubule organizing center organization;GO:0000087//M phase of mitotic cell cycle;GO:0007051//spindle organization;GO:0048232//male gamete generation;GO:0031023//microtubule organizing center organization;GO:0000087//M phase of mitotic cell cycle;GO:0007051//spindle organization;GO:0048232//male gamete generation;GO:0031023//microtubule organizing center organization;GO:0000087//M phase of mitotic cell cycle;GO:0007051//spindle organization;GO:0048232//male gamete generation 2768923 1103.00 0.365 0.435 0.253118936968711 Up 0.0749900937788931 CG18636 CG18636 K01344|1|1e-27|123|gga:395085|protein C (activated) [EC:3.4.21.69];K01310|2|1e-24|113|xtr:496968|chymotrypsin [EC:3.4.21.1];K09632|3|3e-24|112|mdo:100021711|chymotrypsin-like protease [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36698 4211.00 12.84 13.51 0.0733824722033813 Up 0.142649583938714 CG8155 CG8155 K13136|1|1e-40|169|nvi:100114269|gem associated protein 8;K12813|2|4e-17|91.3|nvi:100117259|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 3772232 724.75 1356.925 1531.74 0.174830450401977 Up 0.390371153084137 fabp fatty acid bindin protein, isoform C K08752|1|1e-17|90.5|bta:281758|fatty acid-binding protein 3, muscle and heart GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0005488//binding GO:0006810//transport;GO:0051234//establishment of localization;GO:0051234//establishment of localization 14462436 249.00 0.375 0.01 -5.22881869049588 Down 0.306333377360983 192508 1358.86 9.465 9.615 0.022684351636192 Up 0.0642253335094439 CG5180 CG5180, isoform C - - - - 38541 1566.00 31.395 29.75 -0.0776451438941969 Down 0.189043719455818 Syx17 syntaxin 17, isoform B K08491|1|9e-165|580|dme:Dmel_CG7452|syntaxin 17 GO:0016020//membrane GO:0005488//binding GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis 31493 3236.49 32.48 37.385 0.20290790051946 Up 0.379078061022322 CG32758 CG32758, isoform D K13365|1|5e-10|67.8|gga:422108|Na(+)/H(+) exchange regulatory cofactor NHE-RF1;K02374|3|2e-09|65.9|rno:498331|protein tyrosin phosphatase, non-receptor type 13 (PTPN13);K08789|4|1e-08|62.8|tad:TRIADDRAFT_57859|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - - - 319045 652.96 7.55 7.675 0.0236901060451004 Up 0.0611544049663188 CG31955 CG31955, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - 42676 6435.93 13.08 12.815 -0.0295290622065051 Down 0.0834434024567428 CG6954 wide awake, isoform H - - - GO:0023060;GO:0023060 12798316 745.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 40868 4222.00 6.84 1.875 -1.86710572950265 Down 0.641460837405891 CG14608 CG14608 - - GO:0030247//polysaccharide binding GO:0006022 43104 1337.51 27.975 27.24 -0.038411427851685 Down 0.116728305375776 CLS cardiolipin synthase, isoform D K08744|1|2e-48|193|xtr:780303|cardiolipin synthase [EC:2.7.8.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0016780//phosphotransferase activity, for other substituted phosphate groups GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process 32164 2000.00 11.11 13.81 0.313854502868959 Up 0.405164443270374 CG1492 CG1492 K00681|1|0.0|1053|dme:Dmel_CG1492|gamma-glutamyltranspeptidase [EC:2.3.2.2] - GO:0016755 - 32734 2566.97 53.23 53.2 -0.000813320536933985 Down 0.0427618544445912 CG12991 CG12991, isoform F - - - - 40632 991.00 0.78 0.61 -0.354664881299362 Down 0.116497160216616 Tim17a2 Tim17a2 K10836|1|2e-125|448|dme:Dmel_CG14666|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0031224//intrinsic to membrane;GO:0005743//mitochondrial inner membrane GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 42736 2335.00 6.2 6.16 -0.00933786457933622 Down 0.0472856954167217 CG31365 CG31365 K09228|1|5e-26|119|cfa:484324|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 31393 4368.00 1.84 2.28 0.309328058107729 Up 0.184123629639414 CG12179 CG12179, isoform D - - - - 33014 2542.05 23.155 22.655 -0.0314942661903042 Down 0.0969158631620658 Rab35 Rab35, isoform D K07976|1|4e-104|379|dme:Dmel_CG9575|Rab family, other;K07876|3|3e-74|280|xla:379665|Ras-related protein Rab-35 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity GO:0035556//intracellular signal transduction;GO:0006909//phagocytosis;GO:0051301//cell division;GO:0035556//intracellular signal transduction;GO:0006909//phagocytosis;GO:0051301//cell division 36424 1346.00 12.475 12.19 -0.0333416896044106 Down 0.0846321489895654 sug sugarbabe, isoform B K09233|1|3e-58|226|rno:302946|zinc finger protein GLIS2 GO:0016604//nuclear body GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006810//transport;GO:0006350;GO:0010557//positive regulation of macromolecule biosynthetic process 33304 3359.95 21.475 27.73 0.368789485013653 Up 0.511953506802272 CG4887 CG4887, isoform B K13094|1|0.0|1429|dme:Dmel_CG4887|RNA-binding protein 5/10 GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding GO:0000377 38009 1371.77 79.115 61.235 -0.369594764117403 Down 0.562970545502576 Peb protein ejaculatory bulb, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity GO:0042461//photoreceptor cell development;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009880//embryonic pattern specification;GO:0043409//negative regulation of MAPK cascade;GO:0007424//open tracheal system development;GO:0007320//insemination;GO:0010468//regulation of gene expression;GO:0001736//establishment of planar polarity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010669//epithelial structure maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0035028 10178782 1929.00 311.175 333.435 0.0996793911332463 Up 0.263868709549597 CG31808 CG31808 - - - - 31558 1643.00 5.3 5.535 0.0625909573309909 Up 0.0920948355567296 Spx spliceosomal protein on the X K12831|1|8e-125|447|dme:Dmel_CG3780|splicing factor 3B subunit 4 - - - 14462733 1318.00 0.09 0.035 -1.36257007938471 Down 0.0864152687887994 36318 1694.00 2.545 5.24 1.04190115546176 Up 0.515915995245014 Cyp6t3 Cyp6t3 K00517|1|0.0|989|dme:Dmel_CG8457| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 5740419 140.00 0.405 0.01 -5.33985000288463 Down 0.322183331131951 19835801 393.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 3355132 665.67 61.76 69.4 0.168262910197543 Up 0.362072381455554 CG14464 CG14464, isoform D - - - - 37965 1540.00 9.15 12.885 0.493848888688215 Up 0.497061154404966 CG16912 mitochondrial tyrosyl-tRNA synthetase K01866|1|0.0|929|dme:Dmel_CG16912|tyrosyl-tRNA synthetase [EC:6.1.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0004812//aminoacyl-tRNA ligase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 33719 1794.79 7.56 7.43 -0.0250240236824766 Down 0.0667349095231806 CG8892 CG8892, isoform E - - - - 40559 2691.00 102.72 104.32 0.0222986671087743 Up 0.0904107779685643 lost lost K01934|1|5e-65|249|tca:654948|5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0016882//cyclo-ligase activity;GO:0032559 GO:0007309//oocyte axis specification;GO:0006760//folic acid-containing compound metabolic process;GO:0000377 39637 789.00 0.01 0.17 4.08746284125034 Up 0.187062475234447 CG13463 CG13463 - - - - 34257 870.14 0.83 0.91 0.132755208851772 Up 0.0716219786025624 CG4438 CG4438, isoform B - - - - 19835431 2012.00 7.33 7.82 0.0933554091735404 Up 0.139050323603223 - CG45099 - - - - 3771935 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33901 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 5740488 258.00 1.49 1.815 0.284657217533589 Up 0.151466120723815 CG34263 CG34263 - - - - 32902 2140.97 17.07 17.095 0.00211136440565632 Up 0.0416061286487914 CG7556 CG7556, isoform B K09521|1|0.0|794|dme:Dmel_CG7556|DnaJ homolog subfamily C member 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0010468//regulation of gene expression;GO:0044267//cellular protein metabolic process 31099 903.51 53.81 62.075 0.206138049609429 Up 0.410084533086779 CG14777 CG14777, isoform F K13348|1|2e-111|401|dme:Dmel_CG14777|protein Mpv17 GO:0031224//intrinsic to membrane - - 38242 1797.31 1.15 0.92 -0.321928094887362 Down 0.132347113987584 CG13936 CG13936, isoform D - - - - 38280 1016.00 0.08 0.09 0.169925001442312 Up 0.045667679302602 CG8960 CG8960, isoform B - - - - 34995 837.00 69.185 54.655 -0.340105797134035 Down 0.540252278430855 Cyt-c-d cytochrome c distal, isoform B K08738|1|1e-54|213|dsi:Dsim_GD24072|cytochrome c GO:0031980;GO:0019866//organelle inner membrane;GO:0044425//membrane part GO:0009055//electron carrier activity;GO:0005506//iron ion binding GO:0006091//generation of precursor metabolites and energy;GO:0046668//regulation of retinal cell programmed cell death;GO:0051234//establishment of localization;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 42501 1650.24 154.89 152.465 -0.0227659095968784 Down 0.0916325452384097 Rab11 Rab11, isoform B K07904|1|6e-118|424|dvi:Dvir_GJ23499|Ras-related protein Rab-11A GO:0033267//axon part;GO:0031967;GO:0012505//endomembrane system;GO:0032155;GO:0005798//Golgi-associated vesicle;GO:0010008//endosome membrane;GO:0005815//microtubule organizing center;GO:0033267//axon part;GO:0031967;GO:0012505//endomembrane system;GO:0032155;GO:0005798//Golgi-associated vesicle;GO:0010008//endosome membrane;GO:0005815//microtubule organizing center GO:0032561//guanyl ribonucleotide binding;GO:0000149//SNARE binding;GO:0017111//nucleoside-triphosphatase activity;GO:0001883//purine nucleoside binding;GO:0032561//guanyl ribonucleotide binding;GO:0000149//SNARE binding;GO:0017111//nucleoside-triphosphatase activity;GO:0001883//purine nucleoside binding GO:0006906//vesicle fusion;GO:0051049//regulation of transport;GO:0007017//microtubule-based process;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0044087;GO:0009207;GO:0042051//compound eye photoreceptor development;GO:0006886//intracellular protein transport;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007281//germ cell development;GO:0035556//intracellular signal transduction;GO:0030036//actin cytoskeleton organization;GO:0032506;GO:0048168//regulation of neuronal synaptic plasticity;GO:0033206//cytokinesis after meiosis;GO:0006959//humoral immune response;GO:0006906//vesicle fusion;GO:0051049//regulation of transport;GO:0007017//microtubule-based process;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0044087;GO:0009207;GO:0042051//compound eye photoreceptor development;GO:0006886//intracellular protein transport;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007281//germ cell development;GO:0035556//intracellular signal transduction;GO:0030036//actin cytoskeleton organization;GO:0032506;GO:0048168//regulation of neuronal synaptic plasticity;GO:0033206//cytokinesis after meiosis;GO:0006959//humoral immune response 43621 913.00 0.455 9.51 4.38550689066187 Up 0.791573107911769 Jon99Fii jonah 99Fii K01310|1|3e-125|447|dme:Dmel_CG31362|chymotrypsin [EC:3.4.21.1];K01362|2|3e-125|447|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0032501//multicellular organismal process;GO:0019538//protein metabolic process 38823 2591.00 11.035 12.83 0.217434540810069 Up 0.314852727512878 SMSr SMSr K04714|1|1e-58|228|bfo:BRAFLDRAFT_104157|shingomyelin synthase [EC:2.7.8.27] GO:0031224//intrinsic to membrane - GO:0006684//sphingomyelin metabolic process 39766 3798.43 8.08 14.945 0.8872356989263 Up 0.621087042662792 CG12272 CG12272, isoform C - - - - 246521 2879.00 0.44 0.455 0.0483630215613991 Up 0.0451063267732136 CG30274 CG30274 K00933|1|1e-21|104|tca:660479|creatine kinase [EC:2.7.3.2] - GO:0016772//transferase activity, transferring phosphorus-containing groups - 246431 673.00 0.655 0.6 -0.126532405928932 Down 0.0650508519350152 CG30065 CG30065 - - - - 31390 887.00 0.445 0.495 0.153623189113212 Up 0.0638290846651697 CG12684 CG12684 - - - - 41841 1773.00 0.615 0.53 -0.214594050776041 Down 0.0766411306300357 CG6499 CG6499 K06580|1|7e-06|52.4|oaa:100079743|Rhesus blood group-associated glycoprotein - - - 3771756 1812.44 4.04 6.28 0.636409266139832 Up 0.447331924448554 CG10097 CG10097, isoform C K13356|1|6e-86|320|aga:AgaP_AGAP011736|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 33172 2003.39 204.57 213.4 0.0609655854516273 Up 0.180689472989037 Gs1 glutamine synthetase 1, isoform D K01915|1|0.0|820|dme:Dmel_CG2718|glutamine synthetase [EC:6.3.1.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0016211;GO:0032559;GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0016211;GO:0032559;GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0016211;GO:0032559 GO:0006541//glutamine metabolic process;GO:0006541//glutamine metabolic process;GO:0006541//glutamine metabolic process 19836053 390.00 0.22 0.01 -4.4594316186373 Down 0.222989037115308 34693 1030.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 CG16800 CG16800 - - - - 10178828 488.00 0.51 0.945 0.889817082249577 Up 0.22173424910844 CG42703 CG42703 - - - - 14462750 763.92 34.24 12.55 -1.44799533756301 Down 0.730022454101175 CG44008 CG44008, isoform B - - - - 53510 1994.00 50.72 36.265 -0.483976896569923 Down 0.600746268656716 Ugt86Da Ugt86Da K00699|1|7e-160|564|dpo:Dpse_GA19758|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 31093 1508.00 0.13 0.175 0.428843298803874 Up 0.073702285035002 Gr2a gustatory receptor 2a, isoform C K08471|1|0.0|804|dme:Dmel_CG18531|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 31943 1655.13 9.355 9.44 0.0130492061210574 Up 0.053625676925109 CG2972 CG2972, isoform B K11883|1|0.0|785|dme:Dmel_CG2972|RNA-binding protein NOB1 - - - 48973 4359.95 7.105 7.255 0.0301409648239639 Up 0.06927750627394 Src64B Src oncogene at 64B, isoform K K08253|1|0.0|1094|dme:Dmel_CG7524|non-specific protein-tyrosine kinase [EC:2.7.10.2];K05704|2|0.0|924|aag:AaeL_AAEL004592|proto-oncogene tyrosine-protein kinase Src [EC:2.7.10.2];K05703|4|5e-144|511|tgu:100228220|proto-oncogene tyrosine-protein kinase Fyn [EC:2.7.10.2] GO:0045171//intercellular bridge;GO:0045171//intercellular bridge;GO:0045171//intercellular bridge;GO:0045171//intercellular bridge;GO:0045171//intercellular bridge;GO:0045171//intercellular bridge GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0030832//regulation of actin filament length;GO:0051017//actin filament bundle assembly;GO:0051276//chromosome organization;GO:0008306//associative learning;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007431//salivary gland development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0030832//regulation of actin filament length;GO:0051017//actin filament bundle assembly;GO:0051276//chromosome organization;GO:0008306//associative learning;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007431//salivary gland development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0030832//regulation of actin filament length;GO:0051017//actin filament bundle assembly;GO:0051276//chromosome organization;GO:0008306//associative learning;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007431//salivary gland development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0030832//regulation of actin filament length;GO:0051017//actin filament bundle assembly;GO:0051276//chromosome organization;GO:0008306//associative learning;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007431//salivary gland development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0030832//regulation of actin filament length;GO:0051017//actin filament bundle assembly;GO:0051276//chromosome organization;GO:0008306//associative learning;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007431//salivary gland development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0030832//regulation of actin filament length;GO:0051017//actin filament bundle assembly;GO:0051276//chromosome organization;GO:0008306//associative learning;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007431//salivary gland development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade 12798372 416.00 1.525 1.495 -0.0286637582521434 Down 0.0473517368907674 CG43169 CG43169 - - - - 32285 2675.33 22.375 22.22 -0.0100288656498892 Down 0.0592722229560164 IP3K2 inositol 1,4,5-triphosphate kinase 2, isoform H K00911|1|0.0|880|dsi:Dsim_GD17114|1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] - GO:0051766//inositol trisphosphate kinase activity;GO:0005515//protein binding;GO:0051766//inositol trisphosphate kinase activity;GO:0005515//protein binding;GO:0051766//inositol trisphosphate kinase activity;GO:0005515//protein binding GO:0006020//inositol metabolic process;GO:0006020//inositol metabolic process;GO:0006020//inositol metabolic process 36575 3651.00 1.24 1.175 -0.0776793638218758 Down 0.0616497160216616 Sox15 Sox box protein 15 K04495|1|3e-36|154|rno:312936|transcription factor SOX17 (SOX group F) GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding GO:0007423//sensory organ development;GO:0007444//imaginal disc development;GO:0031647//regulation of protein stability;GO:0006355//regulation of transcription, DNA-dependent;GO:0008283//cell proliferation;GO:0003348;GO:0030178//negative regulation of Wnt receptor signaling pathway;GO:0003143//embryonic heart tube morphogenesis;GO:0006915//apoptotic process;GO:0001709//cell fate determination;GO:0016049//cell growth;GO:0001704//formation of primary germ layer 37785 3070.00 15.02 9.105 -0.722153890537433 Down 0.587901201954828 ken ken and barbie K09230|1|2e-13|78.6|mmu:332221|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007618//mating;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0007487//analia development;GO:0046546//development of primary male sexual characteristics;GO:0007484//imaginal disc-derived genitalia development;GO:0006351//transcription, DNA-dependent;GO:0046545//development of primary female sexual characteristics;GO:0010741//negative regulation of intracellular protein kinase cascade 19835845 296.00 0.315 0.01 -4.97727992349992 Down 0.276482631092326 50266 417.00 760.43 678.715 -0.164009551510597 Down 0.373365473517369 CG7630 CG7630 - - - - 43499 725.00 88.215 81.99 -0.105576030638725 Down 0.26911900673623 Pcd pterin-4a-carbinolamine dehydratase K01724|1|1e-85|315|dme:Dmel_CG1963|4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] - GO:0016836//hydro-lyase activity GO:0042559//pteridine-containing compound biosynthetic process 35223 2033.33 6.57 6.47 -0.0221276583298222 Down 0.0586448289525822 RanGap Ran GTPase activating protein, isoform C K12800|1|8e-11|69.3|dre:561595|NACHT, LRR and PYD domains-containing protein 3;K10165|3|2e-10|68.2|mmu:257632|nucleotide-binding oligomerization domain-containing protein 2 GO:0044424//intracellular part GO:0005488//binding;GO:0005099//Ras GTPase activator activity GO:0007059//chromosome segregation;GO:0051169//nuclear transport;GO:0023060 36899 1524.00 0.15 0.115 -0.383328639551506 Down 0.0672302205785233 CG15614 CG15614 K02155|1|2e-53|211|dme:Dmel_CG9013|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] - - - 40385 4650.04 12.125 13.075 0.108826199172451 Up 0.191982565050852 Cdk12 Cdk12, isoform C K08819|1|0.0|1713|dme:Dmel_CG7597|Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22] - GO:0004674//protein serine/threonine kinase activity;GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0000166//nucleotide binding GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process 41798 3083.79 6.12 6.775 0.146689293548582 Up 0.186732267864219 Rrp6 Rrp6, isoform C K12591|1|0.0|1648|dme:Dmel_CG7292|exosome complex exonuclease RRP6 [EC:3.1.13.-] - - - 10178789 587.00 0.345 0.235 -0.553935605100532 Down 0.101142517500991 36700 439.30 43.485 39.29 -0.146355666323866 Down 0.31789063531898 CG8157 CG8157, isoform B - - - - 3772557 532.97 8.78 10.175 0.212735949618251 Up 0.282360322282393 39031 1930.35 139.34 112.22 -0.312279650483881 Down 0.532624488178576 Galk galactokinase, isoform D K00849|1|0.0|937|dme:Dmel_CG5288|galactokinase [EC:2.7.1.6] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559 GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process 19835150 301.00 0.615 1.3 1.07985330768921 Up 0.291606128648791 37465 3785.51 70.835 79.67 0.169574194135808 Up 0.366266015057456 CG10082 CG10082, isoform B K07756|1|3e-43|177|dre:564478|inositol-hexakisphosphate kinase [EC:2.7.4.21] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0051766//inositol trisphosphate kinase activity;GO:0004428//inositol or phosphatidylinositol kinase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 36399 780.00 186.735 128.865 -0.53513188128975 Down 0.653183199049003 Obp49a Odorant-binding protein 49a - - GO:0005488//binding GO:0051234//establishment of localization 40321 664.59 0.47 0.01 -5.55458885167764 Down 0.34823669264298 CG12984 CG12984, isoform B - - - - 19834982 486.00 0.27 0.63 1.22239242133645 Up 0.213644168537842 14462510 440.00 0.475 0.215 -1.14359085362885 Down 0.175868445383701 34944 692.00 0.63 0.515 -0.290779396316698 Down 0.0960903447364945 CG10839 CG10839, isoform C K10411|1|2e-100|364|dme:Dmel_CG10839|dynein light chain 1, axonemal GO:0005875//microtubule associated complex GO:0016887//ATPase activity;GO:0005488//binding GO:0007017//microtubule-based process 41401 5541.00 17.815 17.17 -0.053202444131165 Down 0.124257033416986 CG42327 CG42327 K04458|1|4e-38|161|tgu:100230601|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 33002 6401.00 3.435 3.285 -0.0644167284957703 Down 0.0767401928411042 Nup205 nucleoporin 205kD, isoform B - - - - 35590 1219.00 231.165 253.765 0.134570122002898 Up 0.319838858803328 SdhB succinate dehydrogenase B K00235|1|2e-164|578|dsi:Dsim_GD10425|succinate dehydrogenase (ubiquinone) iron-sulfur protein [EC:1.3.5.1] GO:0015630//microtubule cytoskeleton;GO:0005746//mitochondrial respiratory chain GO:0051540;GO:0000104//succinate dehydrogenase activity GO:0022904//respiratory electron transport chain;GO:0009060//aerobic respiration 42900 3117.63 3.76 3.345 -0.168726451036176 Down 0.155098401796328 Dis3 Dis3, isoform B K12585|1|0.0|1910|dme:Dmel_CG6413|exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] GO:0000178//exosome (RNase complex);GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0006396//RNA processing 12797948 769.00 0.055 0.385 2.8073549220576 Up 0.234645357284375 50442 845.66 217.495 146.82 -0.566933727925813 Down 0.663320565315018 CG14933 CG14933, isoform C - - GO:0004866//endopeptidase inhibitor activity - 3772668 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 38445 1051.00 19.29 18.75 -0.0409625477784978 Down 0.109859992075023 CG32262 CG32262 K13348|1|9e-29|127|tgu:100229975|protein Mpv17;K13347|2|1e-15|84.0|xtr:448721|peroxisomal membrane protein 2 GO:0031224//intrinsic to membrane - - 8674016 564.00 2.575 1.685 -0.611823840888722 Down 0.297516840575882 Sfp24F seminal fluid protein 24F, isoform B K06560|1|3e-13|74.3|nve:NEMVE_v1g238062|mannose receptor, C type - - - 40067 1325.00 0.265 0.07 -1.9205655325056 Down 0.163683793422269 CG6839 CG6839 - - GO:0043169//cation binding;GO:0003824//catalytic activity - 41615 4337.00 0.93 0.405 -1.19930880822341 Down 0.258255184255713 timeout timeout K03155|1|0.0|2168|dme:Dmel_CG7855|timeless - - - 3772704 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 19834926 4064.45 2.13 3.355 0.655459335974345 Up 0.351968035926562 31539 806.00 0.54 0.605 0.163975735111126 Up 0.0673292827895919 CG5928 CG5928, isoform C - - - - 35104 7916.78 4.8 3.89 -0.303264250622327 Down 0.26251485933166 kon kon-tiki, isoform D K08115|1|0.0|751|dre:567783|chondroitin sulfate proteoglycan 4 - - - 38244 2726.58 40.485 41.11 0.0221018943759298 Up 0.0849293356227711 R roughened, isoform C K04353|1|4e-90|333|dya:Dyak_GE20907|Ras-related protein Rap-1A GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0030054//cell junction;GO:0044444//cytoplasmic part GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0016597//amino acid binding;GO:0004086;GO:0032559;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016743//carboxyl- or carbamoyltransferase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0016597//amino acid binding;GO:0004086;GO:0032559;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016743//carboxyl- or carbamoyltransferase activity GO:0001751//compound eye photoreceptor cell differentiation;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0008360//regulation of cell shape;GO:0043408//regulation of MAPK cascade;GO:0006929//substrate-dependent cell migration;GO:0009064//glutamine family amino acid metabolic process;GO:0019827//stem cell maintenance;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000904//cell morphogenesis involved in differentiation;GO:0001751//compound eye photoreceptor cell differentiation;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0008360//regulation of cell shape;GO:0043408//regulation of MAPK cascade;GO:0006929//substrate-dependent cell migration;GO:0009064//glutamine family amino acid metabolic process;GO:0019827//stem cell maintenance;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000904//cell morphogenesis involved in differentiation 318842 690.00 15.53 2.205 -2.81620726882978 Down 0.758288204992735 CG31606 CG31606 - - - - 43431 1118.00 31.09 32.98 0.0851407820964034 Up 0.207964601769911 CG11842 CG11842 K01312|1|6e-29|128|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K09628|3|1e-25|117|xla:397795|protease, serine 27 [EC:3.4.21.-];K09635|4|3e-24|112|bta:513343|transmembrane protease, serine 4 [EC:3.4.21.-];K01323|5|1e-23|110|ptr:461643|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31750 1242.00 0.105 0.195 0.893084796083488 Up 0.0991942940166425 Or7a odorant receptor 7a K08471|1|0.0|798|dme:Dmel_CG10759|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 14462910 604.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG43895 CG43895 - - - - 19836029 1300.66 7.905 8.84 0.161280907033061 Up 0.22104081363096 33557 640.00 1.31 1.255 -0.0618794475866781 Down 0.0554748381983886 CG8840 CG8840 - - - - 318930 2309.64 1.45 0.97 -0.579996247827807 Down 0.216549993395853 nimA nimrod A, isoform F K01125|1|1e-19|98.6|nve:NEMVE_v1g117798|N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45] GO:0044464//cell part GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 39272 1523.00 0.57 0.505 -0.174678531412947 Down 0.0715889578655396 CG7573 CG7573 K06013|1|2e-28|127|dmo:Dmoj_GI21207|STE24 endopeptidase [EC:3.4.24.84] GO:0044464//cell part GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 44870 2123.00 0.075 0.26 1.79354912253257 Up 0.153711530841368 sub subito, isoform B K10402|1|3e-47|190|xla:446474|kinesin family member 20/23 GO:0005875//microtubule associated complex;GO:0005819//spindle GO:0003774//motor activity;GO:0032559 GO:0051255//spindle midzone assembly;GO:0007143//female meiosis;GO:0007067//mitosis 34790 5637.00 15.325 15.92 0.0549532619655052 Up 0.121879540351341 Sos Son of sevenless K03099|1|0.0|2789|dme:Dmel_CG7793|son of sevenless GO:0043229//intracellular organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003676//nucleic acid binding GO:0007266//Rho protein signal transduction;GO:0007424//open tracheal system development;GO:0065008;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0009966//regulation of signal transduction;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0000578//embryonic axis specification 35021 1487.93 14.92 15.515 0.0564161612734813 Up 0.130993263769647 CG13284 CG13284, isoform E K10251|1|9e-59|227|mcc:714962|beta-keto reductase [EC:1.1.1.-];K00044|2|2e-54|213|xtr:549988|estradiol 17beta-dehydrogenase [EC:1.1.1.62] - GO:0016491//oxidoreductase activity;GO:0016491//oxidoreductase activity GO:0008152//metabolic process;GO:0006909//phagocytosis;GO:0008152//metabolic process;GO:0006909//phagocytosis 33661 500.00 0.25 0.555 1.15055967657538 Up 0.195284638753137 HP6 heterochromatin protein 6 K11586|1|2e-17|88.2|isc:IscW_ISCW000122|chromobox protein 3;K11585|2|2e-17|87.8|xtr:549904|chromobox protein 1 GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0031981//nuclear lumen;GO:0000781//chromosome, telomeric region;GO:0045120//pronucleus;GO:0000775//chromosome, centromeric region;GO:0005700//polytene chromosome GO:0030528//transcription regulator activity;GO:0005515//protein binding GO:0007126//meiosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0000723//telomere maintenance;GO:0006325//chromatin organization 40228 903.00 14.405 15.54 0.10941684324784 Up 0.203936071853124 CG6480 FSHD region gene 1 ortholog K13122|1|1e-126|452|dme:Dmel_CG6480|protein FRG1 - - - 43709 5737.00 5.295 5.52 0.0600375827858326 Up 0.0892220314357416 Gcn2 Gcn2, isoform C K08860|1|0.0|3009|dme:Dmel_CG1609|eukaryotic translation initiation factor 2-alpha kinase [EC:2.7.11.1] GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part GO:0004683//calmodulin-dependent protein kinase activity;GO:0032559 GO:0006412//translation;GO:0000377;GO:0006464//cellular protein modification process 35659 453.00 0.46 0.62 0.430634354329862 Up 0.117091533483027 CG11113 CG11113 - - - - 40112 641.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 CG14095 CG14095 - - - - 41652 1571.00 0.12 0.03 -2 Down 0.110091137234183 yellow-e2 yellow-e2 - - - - 41000 2146.00 6.675 5.725 -0.22149214359061 Down 0.244155329546955 CG9684 CG9684 - - GO:0046914//transition metal ion binding - 43091 2268.00 50 46.68 -0.0991235338421013 Down 0.240291903315282 Npl4 Npl4 ortholog, isoform D K14015|1|0.0|1209|dya:Dyak_GE10682|nuclear protein localization protein 4 homolog GO:0005635//nuclear envelope;GO:0005635//nuclear envelope;GO:0005635//nuclear envelope GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 36284 1968.00 2.915 3.155 0.114144121782053 Up 0.104477611940299 CG8964 CG8964 K05127|1|6e-103|375|dme:Dmel_CG8967|PTK7 protein tyrosine kinase 7 [EC:2.7.10.1] GO:0031224//intrinsic to membrane GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0032559 GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0006464//cellular protein modification process 318721 2107.84 21.41 14.34 -0.578239771683605 Down 0.583443402456743 CG31414 CG31414, isoform C K01201|1|0.0|1180|dme:Dmel_CG31414|glucosylceramidase [EC:3.2.1.45] GO:0000323//lytic vacuole GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding GO:0006643//membrane lipid metabolic process;GO:0007033//vacuole organization 3772580 1631.00 14.98 16.96 0.179098546104448 Up 0.300356623959847 CG13430 CG13430, isoform B K01312|1|3e-45|182|dme:Dmel_CG18444|trypsin [EC:3.4.21.4];K09635|4|2e-43|177|mmu:214523|transmembrane protease, serine 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 10178889 660.00 1.5 1.375 -0.125530882083859 Down 0.0824858010830802 CG42763 CG42763 - - - - 14462526 500.00 0.17 0.01 -4.08746284125034 Down 0.187062475234447 42274 687.00 15.875 16.865 0.0872757264712363 Up 0.178840311715757 snRNP-U1-C small ribonucleoprotein particle U1 subunit C K11095|1|2e-39|161|dya:Dyak_GE25158|U1 small nuclear ribonucleoprotein C GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 38968 2042.00 15.82 18.96 0.261209364425467 Up 0.392583542464668 ZC3H3 ZC3H3 K06093|1|4e-18|93.6|hmg:100206476|partitioning defective protein 6 - GO:0046914//transition metal ion binding GO:0031124//mRNA 3'-end processing;GO:0006913//nucleocytoplasmic transport 41559 2733.88 17.71 15.985 -0.147845467971394 Down 0.267302866199974 CG6225 CG6225, isoform B K01262|1|0.0|1407|dme:Dmel_CG6225|X-Pro aminopeptidase [EC:3.4.11.9] - - - 42400 789.00 98.035 105.525 0.106216018712941 Up 0.272388059701493 CG5023 CG5023 K06084|1|4e-13|75.1|bfo:BRAFLDRAFT_117217|F-box protein 20 - GO:0008092//cytoskeletal protein binding GO:0030036//actin cytoskeleton organization 32033 2354.00 13.7 15.795 0.205292043898984 Up 0.324560824197596 CG42339 CG42339, isoform B K03995|1|1e-08|62.0|cin:100183313|complement component 6;K08619|5|1e-07|58.9|rno:305253|a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-] - GO:0001871;GO:0004888//transmembrane signaling receptor activity GO:0002376//immune system process 37487 9183.00 0.335 0.38 0.181838322985813 Up 0.0605270109628847 CG13492 CG13492 K08654|1|3e-13|79.7|xla:446297|proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-];K02599|3|4e-10|69.3|tca:661022|Notch - - - 38273 4147.70 2.895 1.895 -0.611365499818145 Down 0.314357416457535 CG15822 CG15822, isoform G K08810|1|3e-22|108|xtr:100170157|triple functional domain protein [EC:2.7.11.-] - - - 42693 6913.00 2.38 2.655 0.15775028749621 Up 0.124818385946374 Dcr-1 Dicer-1 K11592|1|0.0|4153|dme:Dmel_CG4792|endoribonuclease Dicer [EC:3.1.26.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031332 GO:0004525//ribonuclease III activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0003723//RNA binding GO:0000278//mitotic cell cycle;GO:0016246//RNA interference;GO:0050658//RNA transport;GO:0048812//neuron projection morphogenesis;GO:0007365//periodic partitioning;GO:0007281//germ cell development;GO:0035196//production of miRNAs involved in gene silencing by miRNA 43928 2933.67 5.335 6.105 0.194503024162978 Up 0.214304583278299 chm chameau, isoform C K11307|1|0.0|1280|dme:Dmel_CG5229|histone acetyltransferase MYST2 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0016746//transferase activity, transferring acyl groups GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 35539 3237.91 24.245 26.265 0.115454330758384 Up 0.248348963148857 Ars2 Ars2, isoform G - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035196//production of miRNAs involved in gene silencing by miRNA 12798575 3061.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 40904 1980.00 86.205 107.96 0.324653426910287 Up 0.537610619469027 alphaTub84D alpha-Tubulin at 84D K07374|1|0.0|855|dvi:Dvir_GJ24568|tubulin alpha GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0015405;GO:0005198//structural molecule activity;GO:0032559 GO:0006810//transport;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0043623//cellular protein complex assembly;GO:0006959//humoral immune response;GO:0007017//microtubule-based process 36774 3133.00 3.09 2.925 -0.0791702134336077 Down 0.0839717342491084 CG8414 CG8414 - - - - 41159 2940.74 4.905 4.695 -0.0631279785654643 Down 0.088033284902919 CG8273 CG8273, isoform B - - GO:0003723//RNA binding - 42794 833.00 16.49 23 0.480042462394271 Up 0.552569013340378 CG10252 CG10252 - - - - 38904 4905.31 4.825 8.905 0.884086668946176 Up 0.56151763307357 CG7504 CG7504, isoform C K10706|1|4e-45|184|mdo:100017004|senataxin [EC:3.6.1.-] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0032559;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0032559 - 44150 693.87 842.535 786.79 -0.0987579977042107 Down 0.266543389248448 RpS15Aa ribosomal protein S15Aa, isoform F K02957|1|5e-71|266|dvi:Dvir_GJ15828|small subunit ribosomal protein S15Ae GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 8674097 1335.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 CG42525 CG42525, isoform B - - GO:0030247//polysaccharide binding GO:0006022 32715 4230.36 2.965 3.085 0.0572383846034142 Up 0.0714238541804253 CG8915 CG8915, isoform B K13184|1|1e-96|355|smm:Smp_035030|ATP-dependent RNA helicase A [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled - 37824 3184.00 11.05 14.755 0.417157551153213 Up 0.478272355038964 Pask PAS kinase K08801|1|0.0|1924|dme:Dmel_CG3105|PAS domain containing serine/threonine kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0060089;GO:0032559 GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0006464//cellular protein modification process 43079 743.00 15.035 15.335 0.0285032986930165 Up 0.0864152687887994 MED28 mediator complex subunit 28 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent 41521 1576.00 46.325 25.55 -0.858467685089645 Down 0.685147272487122 CG5167 CG5167 - - - - 318783 632.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 CG31526 CG31526, isoform C - - - - 12798546 766.00 0.06 0.12 1 Up 0.0856557918372738 34526 767.56 738.24 721.47 -0.0331505029840196 Down 0.117223616431119 RpL9 ribosomal protein L9, isoform C K02940|1|3e-103|374|dsi:Dsim_GD22204|large subunit ribosomal protein L9e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 41674 3228.42 5.7 5.825 0.0312961304895388 Up 0.0667349095231806 omd oocyte maintenance defects, isoform C K13142|1|0.0|1932|dme:Dmel_CG9591|integrator complex subunit 5 - - - 43210 965.00 0.05 0.05 0 - 0.0382380134724607 TwdlD TweedleD - - - - 38703 517.00 0.87 0.01 -6.44294349584873 Down 0.471371021001189 Lcp65Ag1 Lcp65Ag1 - - GO:0005214//structural constituent of chitin-based cuticle GO:0002168//instar larval development 41503 825.07 399.105 290.9 -0.456245056653057 Down 0.631884823669264 GstD1 glutathione S transferase D1, isoform B K00799|1|2e-120|431|dme:Dmel_CG10045|glutathione S-transferase [EC:2.5.1.18] - - - 19835244 1051.00 0.04 0.045 0.169925001442312 Up 0.0382380134724607 3772231 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33857 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 39850 3686.00 2.045 2.275 0.15376570214431 Up 0.111411966715097 spd-2 spindle defective 2 - GO:0005813//centrosome - GO:0007051//spindle organization 39486 669.53 18.295 19.465 0.089432929008196 Up 0.187260599656584 CG11279 CG11279, isoform C - - - - 39950 444.90 653.865 619.025 -0.0789951255309058 Down 0.225399550917976 CG7580 CG7580, isoform D K00418|1|2e-45|181|dsi:Dsim_GD14709|ubiquinol-cytochrome c reductase subunit 8 [EC:1.10.2.2] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0048038//quinone binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0048038//quinone binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity;GO:0048038//quinone binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0003824//catalytic activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 318795 4182.00 0.05 0.035 -0.514573172829758 Down 0.0549134856690001 CG31551 CG31551 K06084|1|8e-13|77.0|spu:591791|F-box protein 20 - - - 32205 5145.50 25.385 29.065 0.195306648502263 Up 0.363029982829217 CG11138 CG11138, isoform E - - - - 246456 809.00 2.97 1 -1.57046293102604 Down 0.489532426363756 CG30098 CG30098 K01344|1|2e-22|105|xla:380116|protein C (activated) [EC:3.4.21.69];K09625|2|1e-21|103|cfa:479874|protease, serine, 21 (testisin) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 53506 1739.00 3.73 5.125 0.458376374137571 Up 0.350680227182671 Ugt86De Ugt86De K00699|1|0.0|1044|dme:Dmel_CG6653|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 31373 3491.00 2.08 2.555 0.296739762796529 Up 0.189472989037115 mei-9 meiotic 9, isoform B K10848|1|0.0|1801|dme:Dmel_CG3697|DNA excision repair protein ERCC-4 [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0004519//endonuclease activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0007059//chromosome segregation;GO:0007131//reciprocal meiotic recombination;GO:0006281//DNA repair 33282 2745.00 3.555 2.825 -0.331598692316865 Down 0.242801479329019 ast asteroid - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0002164//larval development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation 12798379 445.00 0.19 0.215 0.178337241258512 Up 0.0511161009113723 CG43296 CG43296 - - - - 37040 2707.25 23.755 22.27 -0.0931296486230539 Down 0.197728173292828 olf186-F olf186-F, isoform G - - - - 44272 5594.00 3.17 3.565 0.169419236304481 Up 0.151664245145952 tio tiptop, isoform B K09236|1|8e-75|282|dwi:Dwil_GK18714|teashirt - GO:0005488//binding - 35144 2554.98 27.255 30.795 0.176175207874486 Up 0.341500462290318 CG17321 CG17321, isoform B - - - - 4379854 6766.47 15.395 19.885 0.369218694760394 Up 0.482399947166821 CG34114 CG34114, isoform C K06491|1|3e-20|100|dre:767777|neural cell adhesion molecule;K06768|3|1e-18|95.9|dpo:Dpse_GA14672|Down syndrome cell adhesion molecule like 1 GO:0044464//cell part;GO:0044464//cell part - - 38636 2035.00 3.28 2.345 -0.484107892102707 Down 0.29286091665566 mthl2 methuselah-like 2 K04599|1|0.0|1022|dme:Dmel_CG17795|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0010259//multicellular organismal aging;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0006887//exocytosis;GO:0023060 31050 2462.00 34.065 37.7 0.146274316727983 Up 0.312343151499141 CG11638 CG11638 K02183|1|1e-29|132|rno:307100|calmodulin - - - 32089 2616.00 7.765 7.565 -0.0376458421705642 Down 0.080768722757892 Sk1 sphingosine kinase 1, isoform B K04718|1|0.0|1209|dme:Dmel_CG1747|sphingosine kinase [EC:2.7.1.91] - GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006643//membrane lipid metabolic process;GO:0008344//adult locomotory behavior;GO:0033057;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0006643//membrane lipid metabolic process;GO:0008344//adult locomotory behavior;GO:0033057;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process 43464 1152.00 0.495 0.555 0.165059246270496 Up 0.0680227182670717 CG31427 CG31427, isoform F K11140|1|2e-69|262|dme:Dmel_CG11951|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 19836217 395.00 0.01 0.125 3.64385618977472 Up 0.151697265882974 35394 3340.53 3.515 3.23 -0.12199052437861 Down 0.116001849161273 clumsy clumsy, isoform B K05313|1|1e-159|515|dme:Dmel_CG6992|glutamate receptor, ionotropic, invertebrate;K05202|3|2e-153|528|oaa:100074816|glutamate receptor, ionotropic, kainate 2 GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport 41252 9760.81 36.375 47.47 0.384068801746424 Up 0.550026416589618 CG42795 CG42795, isoform G K04574|1|7e-21|105|cfa:442940|neurofilament heavy polypeptide;K11657|4|3e-17|93.2|dre:327618|remodeling and spacing factor 1 GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 41954 1583.00 126.115 71.51 -0.818522970243644 Down 0.703969092590147 sxe2 sex-specific enzyme 2, isoform B K01059|1|8e-34|145|dpo:Dpse_GA18274|lipoprotein lipase [EC:3.1.1.34];K01046|2|3e-32|139|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|2|3e-32|139|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32] - - - 326160 1688.89 15.615 4.83 -1.6928374751848 Down 0.704761590278695 ninaD neither inactivation nor afterpotential D, isoform B K13885|1|1e-51|204|mmu:20778|scavenger receptor class B, member 1 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0046866;GO:0007602//phototransduction;GO:0006726//eye pigment biosynthetic process;GO:0006950//response to stress;GO:0046866;GO:0007602//phototransduction;GO:0006726//eye pigment biosynthetic process;GO:0006950//response to stress 42201 1414.00 6.165 6.71 0.122211871797344 Up 0.158862765816933 CG18600 CG18600 K03005|1|0.0|742|dme:Dmel_CG18600|DNA-directed RNA polymerase I subunit A49 [EC:2.7.7.6] - - - 12798069 1351.00 0.155 0.1 -0.632268215499513 Down 0.075023114515916 43566 1631.00 5.85 5.2 -0.169925001442312 Down 0.191685378417646 CG7928 CG7928 K09228|1|5e-32|139|rno:365214|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 10178932 367.17 1.52 2.685 0.820850764541827 Up 0.358638224805178 MtnE metallothionein E, isoform B - - GO:0046914//transition metal ion binding - 318192 1347.00 1.435 1.08 -0.410019424512219 Down 0.175406155065381 CG32755 CG32755 K01362|1|5e-41|168|dpo:Dpse_GA13240| [EC:3.4.21.-];K01312|2|5e-41|168|gga:396345|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39440 4317.00 1.895 2.85 0.588764070881012 Up 0.306696605468234 caup caupolican - GO:0043231//intracellular membrane-bounded organelle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0003002//regionalization;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006909//phagocytosis;GO:0048592//eye morphogenesis;GO:0048859//formation of anatomical boundary 31105 2093.30 43.42 41.53 -0.0642058541903494 Down 0.165863162065777 rush rush hour, isoform B K05724|1|8e-29|129|dre:556459|FYVE, RhoGEF and PH domain containing 5/6 - - - 38958 1092.00 0.29 0.175 -0.728697978182606 Down 0.108869369964338 mtrm matrimony K07195|1|7e-48|191|dpo:Dpse_GA23958|exocyst complex component 7 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0051726//regulation of cell cycle;GO:0016192//vesicle-mediated transport;GO:0007143//female meiosis;GO:0045132//meiotic chromosome segregation 33074 893.00 0.265 0.49 0.886789389552009 Up 0.153876634526483 CG1304 CG1304 K01362|1|2e-118|424|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|2e-34|146|dme:Dmel_CG18444|trypsin [EC:3.4.21.4];K11997|4|6e-34|144|ame:409206|tripartite motif-containing protein 2/3 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39794 512.00 0.09 0.29 1.68805599368526 Up 0.161636507726852 CG4982 CG4982 - - - - 31762 2569.62 198.76 209.235 0.0740967530686604 Up 0.200865143309999 ND75 NADH:ubiquinone reductase 75kD subunit precursor, isoform B K03934|1|0.0|1393|dme:Dmel_CG2286|NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 3772539 1748.00 7.855 7.9 0.0082413777702688 Up 0.0472856954167217 Spec2 Spec2 - GO:0044464//cell part - - 38808 2463.56 84.325 68.835 -0.29281810577206 Down 0.504127592127856 CG8602 CG8602, isoform B - - - GO:0006810//transport 39409 3238.00 9.9 7.34 -0.431648462123759 Down 0.433727380795139 GRHRII corazonin receptor, isoform B K04280|1|2e-44|181|api:100161233|gonadotropin-releasing hormone receptor GO:0016021//integral to membrane GO:0008188//neuropeptide receptor activity;GO:0016500//protein-hormone receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 39656 531.00 39.75 56.175 0.49897335900819 Up 0.611577070400211 CG6878 CG6878 - GO:0005740//mitochondrial envelope;GO:0031224//intrinsic to membrane - GO:0008283//cell proliferation;GO:0007569//cell aging;GO:0000302//response to reactive oxygen species;GO:0006800//oxygen and reactive oxygen species metabolic process 19834895 957.00 7.875 9.005 0.193446352631635 Up 0.252575617487782 38418 13298.97 17.725 23.88 0.430017209137927 Up 0.53278959186369 kst karst, isoform H K06115|1|0.0|7367|dme:Dmel_CG12008|spectrin beta GO:0044459//plasma membrane part;GO:0030864//cortical actin cytoskeleton;GO:0044459//plasma membrane part;GO:0030864//cortical actin cytoskeleton;GO:0044459//plasma membrane part;GO:0030864//cortical actin cytoskeleton;GO:0044459//plasma membrane part;GO:0030864//cortical actin cytoskeleton;GO:0044459//plasma membrane part;GO:0030864//cortical actin cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007043//cell-cell junction assembly;GO:0016044//cellular membrane organization;GO:0016192//vesicle-mediated transport;GO:0051301//cell division;GO:0007043//cell-cell junction assembly;GO:0016044//cellular membrane organization;GO:0016192//vesicle-mediated transport;GO:0051301//cell division;GO:0007043//cell-cell junction assembly;GO:0016044//cellular membrane organization;GO:0016192//vesicle-mediated transport;GO:0051301//cell division;GO:0007043//cell-cell junction assembly;GO:0016044//cellular membrane organization;GO:0016192//vesicle-mediated transport;GO:0051301//cell division;GO:0007043//cell-cell junction assembly;GO:0016044//cellular membrane organization;GO:0016192//vesicle-mediated transport;GO:0051301//cell division 39957 4062.00 8.375 7.285 -0.201160218167984 Down 0.252674679698851 Edc3 enhancer of decapping 3 K12615|1|0.0|1044|dme:Dmel_CG6311|enhancer of mRNA-decapping protein 3 GO:0015630//microtubule cytoskeleton - - 34731 2672.00 1.315 0.215 -2.6126542345902 Down 0.416160348698983 CG31728 CG31728 K09628|1|7e-42|172|xla:397795|protease, serine 27 [EC:3.4.21.-];K09640|2|3e-41|170|ecb:100146332|transmembrane protease, serine 9 [EC:3.4.21.-];K01310|5|4e-41|169|hsa:1504|chymotrypsin [EC:3.4.21.1] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42960 1416.00 41.235 44.65 0.114790767774476 Up 0.25660414740457 RabX4 RabX4 K07976|1|2e-111|402|dya:Dyak_GE10770|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 41458 2126.03 17.23 20.92 0.279960150021993 Up 0.420188878615771 KLHL18 KLHL18, isoform C K10455|1|0.0|1077|dme:Dmel_CG3571|kelch-like protein 18 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding;GO:0005488//binding GO:0009886//post-embryonic morphogenesis;GO:0009886//post-embryonic morphogenesis 33907 1137.99 59.675 45.655 -0.386353792769168 Down 0.56452252014265 KFase kynurenine formamidase, isoform B K01432|1|3e-27|122|mmu:71562|arylformamidase [EC:3.5.1.9] - GO:0003824//catalytic activity - 35237 5239.44 18.535 23.22 0.325115857046411 Up 0.469158631620658 CG10188 CG10188, isoform C K12791|1|4e-57|224|xla:398353|Rho guanine nucleotide exchange factor 2 GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 14462874 1131.00 0.765 0.65 -0.235020029664197 Down 0.0878681812178048 35705 1293.00 0.06 0.04 -0.584962500721156 Down 0.0550785893541144 CG1339 CG1339 - - GO:0004930//G-protein coupled receptor activity;GO:0005488//binding - 19835633 348.00 0.25 0.01 -4.64385618977472 Down 0.24085325584467 12797990 1000.00 0.275 0.65 1.24100809950379 Up 0.220446440364549 CG43077 CG43077 - - - - 43286 1004.00 0.695 1.03 0.567559454459711 Up 0.175901466120724 CG14262 CG14262 - - GO:0005488//binding - 39107 1888.00 2.885 3.79 0.393626529525609 Up 0.278628978998811 CG3408 CG3408, isoform B K10641|1|5e-13|76.3|oaa:100075388|E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19];K12603|4|4e-11|70.1|ecb:100057912|CCR4-NOT transcription complex subunit 6 [EC:3.1.-.-] GO:0044464//cell part GO:0005488//binding - 41880 7538.78 23.635 33.155 0.488301590294588 Up 0.583146215823537 Rbp RIM-binding protein, isoform J K13738|1|4e-06|55.1|xtr:100158527|CD2-associated protein - - - 37274 554.00 0.225 0.66 1.55254102302878 Up 0.246598864086646 CG10822 CG10822 K10419|1|5e-17|86.3|phu:Phum_PHUM551150|dynein light chain roadblock-type - - - 19834961 802.00 0.055 0.115 1.06413033741972 Up 0.0856557918372738 19835889 440.00 0.57 0.01 -5.83289001416474 Down 0.385946374323075 - CG45546 - - - - 37202 3225.86 70.965 64.915 -0.128555779260359 Down 0.301413287544578 CG10737 CG10737, isoform X K06069|1|6e-06|53.9|ptr:450143|atypical protein kinase C [EC:2.7.11.13] - - - 40599 1668.57 19.995 16.415 -0.284624531237149 Down 0.417250033020737 CG1129 CG1129, isoform E K00966|1|7e-134|478|dme:Dmel_CG1129|mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] - GO:0032561//guanyl ribonucleotide binding;GO:0008905;GO:0032561//guanyl ribonucleotide binding;GO:0008905;GO:0032561//guanyl ribonucleotide binding;GO:0008905 GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 34327 3489.01 19.245 16.495 -0.222454893245908 Down 0.356062607317395 CG5850 CG5850, isoform G - - - - 19835883 1459.00 1.745 0.95 -0.877227617878705 Down 0.303889842821292 40511 949.00 0.305 0.14 -1.12338241550528 Down 0.136573768326509 CG11131 CG11131, isoform B - - - - 36829 1727.23 33.745 32.985 -0.0328636488171729 Down 0.103354906881522 CG7997 CG7997, isoform B K01189|1|0.0|834|dme:Dmel_CG7997|alpha-galactosidase [EC:3.2.1.22] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 41920 1370.00 1.415 2.225 0.653003283021878 Up 0.28695020472857 Pbp45 PSEA-binding protein 45kD - - - - 19835505 862.00 0.415 0.485 0.224873410840203 Up 0.0736032228239334 41098 1137.00 1.05 0.775 -0.438121112391885 Down 0.155263505481442 St2 sulfotransferase 2, isoform B K01014|1|0.0|658|dme:Dmel_CG16733|aryl sulfotransferase [EC:2.8.2.1];K01016|2|7e-159|559|dpo:Dpse_GA14114|estrone sulfotransferase [EC:2.8.2.4];K01025|3|6e-41|167|spu:578298| [EC:2.8.2.-] - GO:0016836//hydro-lyase activity;GO:0016782//transferase activity, transferring sulfur-containing groups - 41158 2305.34 109.98 100.04 -0.136664229080072 Down 0.327367586844538 Kap-alpha3 karyopherin alpha3, isoform D - GO:0005635//nuclear envelope;GO:0005635//nuclear envelope;GO:0005635//nuclear envelope;GO:0005635//nuclear envelope GO:0008565//protein transporter activity;GO:0005488//binding;GO:0008565//protein transporter activity;GO:0005488//binding;GO:0008565//protein transporter activity;GO:0005488//binding;GO:0008565//protein transporter activity;GO:0005488//binding GO:0042993//positive regulation of transcription factor import into nucleus;GO:0009416//response to light stimulus;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0009416//response to light stimulus;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0009416//response to light stimulus;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0009416//response to light stimulus 59226 854.19 0.235 6.615 4.81500849460104 Up 0.774369303922864 CG17242 CG17242, isoform B K01312|1|3e-33|141|dpo:Dpse_GA14937|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 246560 443.00 2.095 1.75 -0.259595321867023 Down 0.154636111478008 CG30354 CG30354, isoform B K00416|1|8e-45|177|dme:Dmel_CG30354|ubiquinol-cytochrome c reductase subunit 6 [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity GO:0022904//respiratory electron transport chain 37565 1190.00 1.07 2.025 0.92031111137084 Up 0.333707568352926 CG10344 CG10344, isoform B - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 40953 871.00 18.745 27.375 0.546353139087808 Up 0.592524105138027 CG11035 CG11035 K09504|1|2e-13|76.3|tca:662253|DnaJ homolog subfamily A member 3;K09502|2|5e-13|74.7|bta:784704|DnaJ homolog subfamily A member 1 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006950//response to stress 31724 5078.00 7.645 7.615 -0.00567246487351234 Down 0.0453704926693964 Upf2 Upf2 - - - - 33657 1411.00 1.415 1.76 0.314773375805415 Up 0.161735569937921 CG15436 CG15436 K09228|1|3e-59|229|ptr:742511|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 37668 1384.00 1.97 0.98 -1.00734197534117 Down 0.3452318055739 CG9876 CG9876 K09329|1|9e-28|124|mcc:702704|paired mesoderm homeobox protein GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048704//embryonic skeletal system morphogenesis;GO:0048514//blood vessel morphogenesis;GO:0009888//tissue development;GO:0042471//ear morphogenesis;GO:0010468//regulation of gene expression;GO:0008589//regulation of smoothened signaling pathway;GO:0035108//limb morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0008284//positive regulation of cell proliferation 34687 1382.00 0.525 0.435 -0.271302021817394 Down 0.0839717342491084 CG15483 CG15483 K00741|1|0.0|820|dme:Dmel_CG15483|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149] - - GO:0002118//aggressive behavior 38534 3375.97 46.025 45.1 -0.0292902880945254 Down 0.105402192576938 Cip4 Cdc42-interacting protein 4, isoform K K07196|1|4e-88|326|mmu:106628|thyroid hormone receptor interactor 10 GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0005488//binding GO:0007010//cytoskeleton organization;GO:0009888//tissue development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0009888//tissue development;GO:0023060 43946 9233.48 3.81 2.765 -0.462511517258615 Down 0.305276713776251 wb wing blister, isoform G K05637|1|0.0|732|mmu:16772|laminin, alpha 1 GO:0043256//laminin complex;GO:0005605//basal lamina;GO:0005605//basal lamina;GO:0005605//basal lamina;GO:0005605//basal lamina GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:2000026//regulation of multicellular organismal development;GO:0016477//cell migration;GO:0007155//cell adhesion;GO:0007154//cell communication;GO:0007155//cell adhesion;GO:0007154//cell communication;GO:0050789//regulation of biological process;GO:0007155//cell adhesion;GO:0007154//cell communication;GO:0050789//regulation of biological process;GO:0007155//cell adhesion;GO:0007154//cell communication;GO:0050789//regulation of biological process;GO:0007155//cell adhesion;GO:0007154//cell communication;GO:0050789//regulation of biological process 33803 2908.41 82.075 75.9 -0.112842959157514 Down 0.268953903051116 CG11147 CG11147, isoform B K05643|1|2e-27|125|mdo:100013281|ATP-binding cassette, subfamily A (ABC1), member 3 GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0051234//establishment of localization 41612 3180.88 1.195 1.225 0.0357711310218219 Up 0.0480451723682473 sim single-minded, isoform D K09100|1|0.0|964|dme:Dmel_CG7771|single-minded - - - 43726 737.00 5.415 5.385 -0.00801499306411973 Down 0.0453704926693964 CG11539 CG11539, isoform B - - GO:0016407//acetyltransferase activity - 33372 2130.00 20.605 19.94 -0.0473290538823034 Down 0.124917448157443 CG7289 CG7289 - - - - 34392 2577.00 2.88 2 -0.526068811667588 Down 0.288832386738872 RnrL ribonucleoside diphosphate reductase large subunit K10807|1|0.0|1652|dme:Dmel_CG5371|ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] GO:0043234//protein complex GO:0016728;GO:0032559 GO:0006259//DNA metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0051262//protein tetramerization;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 37032 1875.00 0.635 0.67 0.0774045036856068 Up 0.0531303658697662 CG6362 CG6362 - - - - 40666 5625.65 34.375 35.58 0.0497067970804132 Up 0.14086646413948 CG2519 CG2519, isoform C - - - - 12797888 584.00 1.73 1.11 -0.640212361286618 Down 0.250198124422137 CG43062 CG43062 - - - - 40574 1785.00 0.07 0.265 1.9205655325056 Up 0.163683793422269 Mur82C mucin related 82C - - - - 12798535 136.00 0.01 0.575 5.84549005094437 Up 0.385946374323075 19834779 522.00 2.225 2.75 0.305626282558262 Up 0.201129309206181 42813 4332.00 6.975 6.01 -0.214828226005364 Down 0.241744815744287 tst twister, isoform B K12599|1|0.0|2320|dme:Dmel_CG10210|antiviral helicase SKI2 [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000380//alternative mRNA splicing, via spliceosome 34710 1829.00 16.55 12.84 -0.366186014572277 Down 0.46374323074891 CG5439 CG5439 K10392|1|9e-13|75.5|mdo:100033264|kinesin family member 1/13/14 - GO:0005543//phospholipid binding GO:0009987//cellular process 5740583 388.00 0.23 0.01 -4.52356195605701 Down 0.229362039360719 CG13051 CG13051 - - - - 19835086 1035.58 33.195 32 -0.0528940467474431 Down 0.14086646413948 318937 1483.00 1.085 0.475 -1.19169562411353 Down 0.280213974375908 CG31780 CG31780 K01312|1|1e-29|131|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|2|7e-26|118|cfa:475624|plasma kallikrein [EC:3.4.21.34];K01316|3|3e-25|116|mmu:19146|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K09628|4|5e-25|115|xla:397795|protease, serine 27 [EC:3.4.21.-];K09614|5|8e-25|115|dpo:Dpse_GA15245|corin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37121 2985.68 35.01 33.785 -0.0513842066466523 Down 0.141460837405891 slim scruin like at the midline, isoform C K10450|1|5e-08|60.5|dre:492362|kelch-like protein 12 - - - 44380 1650.87 171.63 117.19 -0.550452282543821 Down 0.655527671377625 fok fledgling of Klp38B, isoform E - - - - 261626 1500.00 1.885 2.105 0.159255709797732 Up 0.110553427552503 CG31495 CG31495, isoform B K06027|1|6e-58|225|dme:Dmel_CG33101|vesicle-fusing ATPase [EC:3.6.4.6] - GO:0016462//pyrophosphatase activity;GO:0032559 GO:0016192//vesicle-mediated transport;GO:0065008;GO:0048638//regulation of developmental growth;GO:0007268//synaptic transmission;GO:0051649//establishment of localization in cell 33483 1073.00 0.625 0.135 -2.21089678249862 Down 0.275326905296526 CG18557 CG18557 K01310|1|8e-26|117|xtr:496968|chymotrypsin [EC:3.4.21.1];K08664|2|1e-25|117|rno:192107|protease, serine, 8 (prostasin) [EC:3.4.21.-];K09626|3|2e-25|116|rno:302971|protease, serine, 22 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34432 1198.00 10.785 10.55 -0.0317831775659064 Down 0.0789195614846123 holn1 hole-in-one K13099|1|3e-156|551|dme:Dmel_CG5198|CD2 antigen cytoplasmic tail-binding protein 2 - - GO:0006909//phagocytosis 37306 2548.68 45.28 52.06 0.20130135357223 Up 0.392979791308942 CG8929 CG8929, isoform D - - - - 32110 772.00 1.445 1.84 0.348636273556334 Up 0.180293224144763 CG2533 CG2533 - - - - 33853 589.00 14.55 15.52 0.0931094043914815 Up 0.177420420023775 CG13994 CG13994, isoform B - - - - 31214 2728.44 42.53 41.86 -0.0229085433700545 Down 0.0855567296262053 CG2924 CG2924, isoform E K10582|1|0.0|746|dme:Dmel_CG2924|ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19] - - - 32119 5960.95 37.33 46.875 0.328483181854898 Up 0.517401928411042 bif bifocal, isoform F - - GO:0019903//protein phosphatase binding;GO:0003779//actin binding;GO:0015631//tubulin binding;GO:0019903//protein phosphatase binding;GO:0003779//actin binding;GO:0015631//tubulin binding GO:0030308//negative regulation of cell growth;GO:0006935//chemotaxis;GO:0007143//female meiosis;GO:0030308//negative regulation of cell growth;GO:0006935//chemotaxis;GO:0007143//female meiosis 36196 421.00 0.525 0.14 -1.90689059560852 Down 0.23586712455422 Cpr47Eg cuticular protein 47Eg - - GO:0042302//structural constituent of cuticle GO:0051234//establishment of localization 12798413 846.00 1.035 0.33 -1.64909283814087 Down 0.316734909523181 CG43335 CG43335 - - - - 40534 1235.00 0.415 0.01 -5.37503943134692 Down 0.323239994716682 TwdlF TweedleF - - - - 42341 715.03 534.265 465.675 -0.198232076076751 Down 0.429500726456215 Vha13 vacuolar H[+] ATPase 13kD subunit, isoform B K02152|1|1e-40|166|dsi:Dsim_GD20107|V-type H+-transporting ATPase subunit G [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006818//hydrogen transport 43812 3273.98 12.95 17.52 0.436050677027257 Up 0.507000396248844 ey eyeless, isoform D K08031|1|7e-66|252|xtr:448447|paired box protein 6 - - - 12798323 1526.00 0.415 0.79 0.928741316830178 Up 0.210309074098534 CG43327 CG43327 - - - - 5740185 426.33 518.42 459.39 -0.174401924203022 Down 0.387498348963149 Ucrh Ubiquinol-cytochrome C reductase complex 11 kDa protein, isoform F K00416|1|3e-34|143|dme:Dmel_CG30354|ubiquinol-cytochrome c reductase subunit 6 [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 35041 4274.34 13.235 13.485 0.0269973267402049 Up 0.081197992339189 Lrch Leucine-rich-repeats and calponin homology domain protein, isoform C K10130|1|3e-14|81.3|tgu:100225786|leucine-rich repeats and death domain-containing protein - GO:0005488//binding;GO:0005488//binding - 31181 5789.35 11.175 12.43 0.153551464981805 Up 0.242372209747722 ph-p polyhomeotic proximal, isoform D K11456|1|0.0|767|dme:Dmel_CG18412|polyhomeotic-like protein 1 GO:0031981//nuclear lumen;GO:0031519//PcG protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0016458//gene silencing;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0002165//instar larval or pupal development;GO:0021953//central nervous system neuron differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007293//germarium-derived egg chamber formation 19836210 346.00 0.01 0.31 4.95419631038688 Up 0.276482631092326 19836167 507.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 12798449 441.00 1.37 0.68 -1.01056924171019 Down 0.291771232333906 CG43175 CG43175, isoform B - - - - 318936 368.48 14.94 12.53 -0.253793733467376 Down 0.36005811649716 Acp24A4 accessory gland protein 24A4, isoform C K03909|1|2e-09|60.1|cfa:403921|tissue factor pathway inhibitor;K06238|2|3e-09|59.7|cfa:403582|collagen, type VI, alpha;K04520|3|4e-09|59.3|dre:58083|amyloid beta (A4) protein;K08117|5|4e-09|59.3|tgu:100222411|amyloid beta (A4) precursor-like protein 2 - GO:0004866//endopeptidase inhibitor activity - 40508 3846.98 19.44 19.29 -0.0111750755566776 Down 0.0581825386342623 Chro chromator, isoform E K01873|1|2e-06|55.8|bmy:Bm1_32860|valyl-tRNA synthetase [EC:6.1.1.9] GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006325//chromatin organization;GO:0006325//chromatin organization;GO:0006325//chromatin organization 43149 9485.81 17.33 21.32 0.298935783599006 Up 0.439274864614978 Nf1 neurofibromin 1, isoform F K08052|1|0.0|5338|dme:Dmel_CG8318|neurofibromin 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity GO:0007613//memory;GO:0035264//multicellular organism growth;GO:0010259//multicellular organismal aging;GO:0007626//locomotory behavior;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008306//associative learning;GO:0042065;GO:0006950//response to stress;GO:0007613//memory;GO:0035264//multicellular organism growth;GO:0010259//multicellular organismal aging;GO:0007626//locomotory behavior;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008306//associative learning;GO:0042065;GO:0006950//response to stress;GO:0007613//memory;GO:0035264//multicellular organism growth;GO:0010259//multicellular organismal aging;GO:0007626//locomotory behavior;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008306//associative learning;GO:0042065;GO:0006950//response to stress 36791 2746.03 164.29 177.43 0.111005293212165 Up 0.279685642583542 Lis-1 Lissencephaly-1, isoform G K01062|1|0.0|783|dsi:Dsim_GD11168|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0043005//neuron projection;GO:0044297//cell body;GO:0000775//chromosome, centromeric region;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0044444//cytoplasmic part;GO:0000922//spindle pole;GO:0043005//neuron projection;GO:0044297//cell body;GO:0000775//chromosome, centromeric region;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0044444//cytoplasmic part;GO:0000922//spindle pole;GO:0043005//neuron projection;GO:0044297//cell body;GO:0000775//chromosome, centromeric region;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0044444//cytoplasmic part;GO:0000922//spindle pole GO:0005515//protein binding;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0016887//ATPase activity GO:0007097//nuclear migration;GO:0000075//cell cycle checkpoint;GO:0051297//centrosome organization;GO:0048812//neuron projection morphogenesis;GO:0007051//spindle organization;GO:0010970//microtubule-based transport;GO:0051276//chromosome organization;GO:0015031//protein transport;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006403//RNA localization;GO:0003002//regionalization;GO:0007420//brain development;GO:0008105//asymmetric protein localization;GO:0001709//cell fate determination;GO:0009887//organ morphogenesis;GO:0019222//regulation of metabolic process;GO:0000087//M phase of mitotic cell cycle;GO:0043954//cellular component maintenance;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007097//nuclear migration;GO:0000075//cell cycle checkpoint;GO:0051297//centrosome organization;GO:0048812//neuron projection morphogenesis;GO:0007051//spindle organization;GO:0010970//microtubule-based transport;GO:0051276//chromosome organization;GO:0015031//protein transport;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006403//RNA localization;GO:0003002//regionalization;GO:0007420//brain development;GO:0008105//asymmetric protein localization;GO:0001709//cell fate determination;GO:0009887//organ morphogenesis;GO:0019222//regulation of metabolic process;GO:0000087//M phase of mitotic cell cycle;GO:0043954//cellular component maintenance;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007097//nuclear migration;GO:0000075//cell cycle checkpoint;GO:0051297//centrosome organization;GO:0048812//neuron projection morphogenesis;GO:0007051//spindle organization;GO:0010970//microtubule-based transport;GO:0051276//chromosome organization;GO:0015031//protein transport;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006403//RNA localization;GO:0003002//regionalization;GO:0007420//brain development;GO:0008105//asymmetric protein localization;GO:0001709//cell fate determination;GO:0009887//organ morphogenesis;GO:0019222//regulation of metabolic process;GO:0000087//M phase of mitotic cell cycle;GO:0043954//cellular component maintenance;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation 31770 3426.00 0.27 0.71 1.39485961734121 Up 0.24270241711795 CG1387 CG1387 - - - - 36383 2932.08 101.92 98.22 -0.0533484550609908 Down 0.154966318848237 Amph amphiphysin, isoform C K12562|1|0.0|946|dme:Dmel_CG8604|amphiphysin GO:0044424//intracellular part;GO:0016020//membrane GO:0005488//binding GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0001505//regulation of neurotransmitter levels;GO:0033036;GO:0006897//endocytosis;GO:0006936//muscle contraction 32832 1645.00 25.565 20.66 -0.307329771821884 Down 0.462356359793951 psh persephone K01312|1|6e-103|374|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4];K01343|3|1e-27|124|gga:426791|tissue plasminogen activator [EC:3.4.21.68];K09628|4|2e-27|124|xla:397795|protease, serine 27 [EC:3.4.21.-] GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0008063//Toll signaling pathway 43810 6471.12 18.34 24.83 0.437090622581786 Up 0.54101175538238 CG11360 CG11360, isoform E - - - - 31825 557.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG12662 CG12662 - - - - 38727 3547.00 32.61 24.885 -0.390038054071446 Down 0.534737815348039 Best2 bestrophin 2 K13878|1|4e-88|327|tgu:100229562|bestrophin-1;K13880|3|7e-87|322|mdo:100015513|bestrophin-3 - - - 36887 1378.00 2.32 2.18 -0.0897966703506459 Down 0.0794148725399551 Fen1 flap endonuclease 1 K04799|1|0.0|666|dme:Dmel_CG8648|flap endonuclease-1 [EC:3.-.-.-] - - - 3772173 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33863 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 40863 4392.91 82.19 89.815 0.127993536652232 Up 0.306168273675868 lap like-AP180, isoform J - GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0012505//endomembrane system GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding GO:0006901//vesicle coating;GO:0009416//response to light stimulus;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0006901//vesicle coating;GO:0009416//response to light stimulus;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0006901//vesicle coating;GO:0009416//response to light stimulus;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis 41391 4338.00 13.635 15.23 0.159601241572029 Up 0.268293488310659 CG6791 CG6791, isoform B K09228|1|5e-13|77.4|rno:499056|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 39008 568.00 0.145 0.165 0.186413124230881 Up 0.0514463082816008 CG13311 CG13311 - - GO:0042578//phosphoric ester hydrolase activity - 39180 3323.90 14.275 16.88 0.24182415845698 Up 0.362897899881125 dpr10 dpr10, isoform D - - - - 41060 2448.73 14.52 14.9 0.0372708773537734 Up 0.100250957601374 CG8379 CG8379, isoform B - - - - 31642 1070.00 28.695 28.775 0.00401655395232426 Up 0.0449742438251222 CG3040 CG3040 K10130|1|1e-12|74.3|rno:293625|leucine-rich repeats and death domain-containing protein;K12796|5|7e-12|71.6|api:100161448|erbb2-interacting protein - - - 34434 1132.82 6.195 7.09 0.194681345098915 Up 0.227843085457667 CG13142 CG13142, isoform C - - - - 32348 1121.00 8.075 7.86 -0.0389329473226807 Down 0.0819904900277374 CG11095 CG11095 K01529|1|6e-22|105|mmu:66387| [EC:3.6.1.-] - GO:0003824//catalytic activity - 42969 542.00 19.88 17.405 -0.191815942838603 Down 0.326938317263241 CG13641 CG13641 - - - - 41694 2649.02 18.57 17.02 -0.125742778249458 Down 0.243098665962224 Nsf2 N-ethylmaleimide-sensitive factor 2, isoform C K06027|1|0.0|1447|dme:Dmel_CG33101|vesicle-fusing ATPase [EC:3.6.4.6] - - - 38509 552.00 0.08 0.01 -3 Down 0.110718531237617 Cpr64Ab cuticular protein 64Ab - - GO:0005198//structural molecule activity - 5740834 407.00 0.845 0.49 -0.786169592166976 Down 0.197133800026417 CG16824 CG16824 - - - - 35906 1824.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 CG13744 CG13744 K01312|1|4e-47|188|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01315|2|2e-38|160|ptr:463117|plasminogen [EC:3.4.21.7];K01324|3|6e-38|158|cfa:475624|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43375 1154.00 0.11 0.05 -1.13750352374993 Down 0.0858869369964338 Or98b odorant receptor 98b K08471|1|1e-135|482|dme:Dmel_CG1867|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 326245 1391.00 7.88 7.43 -0.08483341891778 Down 0.129375247655528 CG33052 CG33052 - GO:0044424//intracellular part GO:0005488//binding - 45826 3422.54 63.63 59.32 -0.101188523797081 Down 0.246037511557258 bel belle, isoform B K11594|1|0.0|1125|dme:Dmel_CG9748|ATP-dependent RNA helicase [EC:3.6.4.13] GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0031332;GO:0044444//cytoplasmic part GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0002164//larval development;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0035194//posttranscriptional gene silencing by RNA 35683 2346.36 5.92 5.545 -0.0944097154672399 Down 0.124455157839123 CG1603 CG1603, isoform B K09228|1|2e-25|117|mmu:630579|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 36192 634.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 Cpr47Ed cuticular protein 47Ed - - GO:0042302//structural constituent of cuticle - 33501 1850.00 15.295 19.99 0.386218365186425 Up 0.493990225861841 gammaTub23C gamma-Tubulin at 23C K10389|1|0.0|954|dme:Dmel_CG3157|tubulin gamma GO:0000931//gamma-tubulin large complex GO:0017111//nucleoside-triphosphatase activity;GO:0008017//microtubule binding;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0000278//mitotic cell cycle;GO:0043623//cellular protein complex assembly;GO:0051297//centrosome organization;GO:0051304//chromosome separation 40300 6083.00 0.19 0.145 -0.389946518316013 Down 0.0673292827895919 Spc105R Spc105-related, isoform B - - - - 42328 1413.00 0.675 1.17 0.793549122532573 Up 0.232300884955752 CG15025 CG15025 - - GO:0003824//catalytic activity - 31684 1299.25 42.36 36.995 -0.195372290552049 Down 0.383271694624224 Rab39 Rab39, isoform B K07976|1|1e-123|442|dya:Dyak_GE15730|Rab family, other - - - 19835438 860.00 7.535 2.21 -1.76956114220639 Down 0.646579051644433 35127 843.00 17.445 15.44 -0.176140844926294 Down 0.301050059437327 CG10343 CG10343 - - - - 12798256 615.00 6.59 6.465 -0.0276280951977974 Down 0.0651829348831066 CG43273 CG43273, isoform B - - - - 318034 821.00 2.285 2.925 0.356242459412697 Up 0.230781931052701 CG32450 CG32450 - - - - 19836123 322.00 9.885 7.55 -0.388764321516767 Down 0.41183463214899 19835332 1291.00 0.33 1.07 1.69707286704269 Up 0.326773213578127 39218 2723.00 14.425 16.255 0.172312237157511 Up 0.287214370624752 CG6418 CG6418 K12835|1|0.0|1306|dme:Dmel_CG6418|ATP-dependent RNA helicase DDX42 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled - 41052 2139.00 5.215 4.71 -0.146940192906983 Down 0.164410249636772 Ir85a ionotropic receptor 85a K05331|1|8e-11|68.9|tca:663613|chloride channel, invertebrate;K00683|2|2e-07|57.4|tca:659407|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] GO:0044464//cell part GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity - 49425 1012.00 29.9 30.295 0.0189342211414747 Up 0.0805045568617092 mRpL4 mitochondrial ribosomal protein L4 K02926|1|2e-26|119|isc:IscW_ISCW020778|large subunit ribosomal protein L4 GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression 35273 2008.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 CG10481 CG10481 - GO:0031224//intrinsic to membrane - - 19835861 963.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 - CG44532 - - - - 39447 1032.00 18.915 16.64 -0.184875342908284 Down 0.311847840443799 CG10973 CG10973 K09562|1|2e-152|538|dme:Dmel_CG10973|hsp70-interacting protein - - - 42630 1876.00 19.92 22.345 0.165734397326929 Up 0.309206181481971 CG13850 CG13850, isoform B - - GO:0016301//kinase activity;GO:0032559 GO:0012501//programmed cell death 246652 2379.00 1.67 1.925 0.205010343108212 Up 0.125908070268128 CG30496 CG30496 - - - - 39040 1286.00 2.625 3.29 0.325770161181757 Up 0.230451723682473 CG5144 CG5144 K00934|1|0.0|731|dme:Dmel_CG5144|arginine kinase [EC:2.7.3.3];K00933|2|0.0|712|dsi:Dsim_GD14150|creatine kinase [EC:2.7.3.2] - GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559 GO:0006796//phosphate-containing compound metabolic process 39846 1537.38 420.49 426.855 0.0216745874591204 Up 0.0931845198784837 CG4169 CG4169, isoform B K00415|1|0.0|762|dme:Dmel_CG4169|ubiquinol-cytochrome c reductase core subunit 2 [EC:1.10.2.2] GO:0015630//microtubule cytoskeleton;GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0022904//respiratory electron transport chain 41820 1428.00 33.185 8.285 -2.00195767167137 Down 0.758948619733192 CG6912 CG6912 - - - - 53446 3014.00 1.465 1.035 -0.501269896922922 Down 0.198685774666491 HGTX HGTX K08030|1|3e-46|187|dre:436748|homeobox protein Nkx-6.1;K09350|4|7e-43|176|dre:565782|homeobox protein Nkx-6.2 - GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0006350 41988 4912.72 1.05 0.9 -0.222392421336448 Down 0.0979395060097741 ss spineless, isoform D K09093|1|8e-94|346|dre:554265|aryl hydrocarbon receptor GO:0043231//intracellular membrane-bounded organelle GO:0004871//signal transducer activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009886//post-embryonic morphogenesis;GO:0023060;GO:0010468//regulation of gene expression;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0035110;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006351//transcription, DNA-dependent 42705 1696.00 0.895 2.79 1.64030553456493 Up 0.486626601505746 CG13840 CG13840 - - - GO:0006810//transport 33711 1041.00 23.115 25.225 0.126024906757778 Up 0.262878087438912 Scox synthesis of cytochrome c oxidase K07152|1|8e-137|486|dse:Dsec_GM18054| GO:0019866//organelle inner membrane GO:0046914//transition metal ion binding GO:0000041//transition metal ion transport;GO:0043623//cellular protein complex assembly;GO:0030005 5740648 1975.00 62.905 95.885 0.608130447247675 Up 0.660810989301281 19835865 468.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 - CG44253 K08745|1|7e-13|63.2|dya:Dyak_GE14256|solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] - GO:0015245//fatty acid transporter activity - 32792 1341.00 3.74 3.51 -0.0915672395830762 Down 0.0974111742174085 Taf8 TBP-associated factor 8 - GO:0005667//transcription factor complex GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding - 3771771 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33815 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 318594 1676.00 0.5 0.505 0.0143552929770701 Up 0.041044776119403 CG31106 CG31106 K06258|1|8e-64|244|tca:662982|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 GO:0031224//intrinsic to membrane - GO:0006810//transport 32384 10025.00 0.08 0.16 1 Up 0.0978734645357284 Muc12Ea mucin 12Ea K10955|1|0.0|1093|hsa:4583|intestinal mucin-2 - - - 34618 2218.30 16.755 18.9 0.173794547903964 Up 0.299266939638093 Tom70 translocase of outer membrane 70, isoform C K09667|1|5e-12|73.2|nve:NEMVE_v1g239520|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - GO:0008320//protein transmembrane transporter activity;GO:0008320//protein transmembrane transporter activity;GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting;GO:0006605//protein targeting;GO:0006605//protein targeting 19836161 1276.00 0.12 0.22 0.874469117916141 Up 0.103255844670453 31219 1643.00 0.915 0.945 0.0465425859370306 Up 0.0483423590014529 CG2854 CG2854 - - - - 31591 8393.11 50.525 46.785 -0.11095136317179 Down 0.25937788931449 CG34417 CG34417, isoform Y K04574|1|4e-16|90.1|gga:417020|neurofilament heavy polypeptide;K12567|4|1e-13|81.6|mmu:22138|titin [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0009888//tissue development;GO:0009888//tissue development;GO:0009888//tissue development;GO:0009888//tissue development 37762 4783.48 35.39 12.045 -1.55490736818676 Down 0.737782327301545 CG9850 CG9850, isoform F K08617|1|5e-18|94.4|gga:418479|a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-];K08630|3|1e-16|90.1|oaa:100080561|a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 19835927 430.00 1.1 0.96 -0.196397212803504 Down 0.093778893144895 38677 2919.00 20.925 22.59 0.110456647955379 Up 0.227017567032096 CG32406 PVR adaptor protein K00665|1|9e-07|56.2|dpe:Dper_GL12292|fatty acid synthase, animal type [EC:2.3.1.85];K08895|2|9e-07|56.2|ecb:100060563|src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites [EC:2.7.10.2];K06619|3|3e-06|54.7|dan:Dana_GF10512|proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2] - GO:0005488//binding - 32337 2737.35 87.33 98.72 0.176865054305496 Up 0.384493461894069 Pdcd4 programmed cell death 4 ortholog, isoform D K03260|1|1e-06|55.8|bfo:BRAFLDRAFT_122212|translation initiation factor eIF-4F - - - 36356 1832.00 2.975 1.615 -0.881355503501381 Down 0.388455950336812 CG8834 CG8834, isoform B K01904|1|1e-45|184|spu:581911|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 19835314 576.00 0.23 0.01 -4.52356195605701 Down 0.229362039360719 41513 2077.00 5.415 6.335 0.226383281532482 Up 0.243428873332453 CG34402 CG34402, isoform E K09608|1|5e-12|73.2|dre:474335|tolloid-like protein 1 [EC:3.4.24.-];K13047|2|2e-11|70.9|tgu:100224187|tolloid-like protein 2 [EC:3.4.24.-] - - - 318237 675.00 1.65 2.76 0.742202242532353 Up 0.344769515255581 CG32832 CG32832, isoform B - - - - 42084 717.00 1.985 1.305 -0.605089200573073 Down 0.260467573636244 CG31418 CG31418 - - - - 12798515 722.00 117.02 46.6 -1.32835326327763 Down 0.751783119799234 CG43092 CG43092 - - - - 39433 1128.00 59.48 53.065 -0.164644028828014 Down 0.343646810196804 eIF-2beta eukaryotic initiation factor 2beta K03238|1|5e-134|477|dme:Dmel_CG4153|translation initiation factor eIF-2 beta subunit GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding GO:0006413//translational initiation;GO:0007052//mitotic spindle organization;GO:0016198//axon choice point recognition 38401 935.00 0.255 0.19 -0.42449782852791 Down 0.0781931052701096 CG12078 CG12078, isoform B K01090|1|1e-39|163|dre:492343|protein phosphatase [EC:3.1.3.16] GO:0016020//membrane GO:0016791//phosphatase activity - 36172 1066.04 0.17 0.505 1.57074864150146 Up 0.215262184651961 CG9084 CG9084, isoform E - - - - 36099 670.96 4.075 4.335 0.0892319341033949 Up 0.103751155725796 CG11825 CG11825, isoform D - GO:0031224//intrinsic to membrane - - 31085 690.00 22.415 4.895 -2.19508373444699 Down 0.749900937788931 CG14770 CG14770 - - - - 37489 788.00 10.6 4.765 -1.15351614554062 Down 0.625445779949808 CG4377 CG4377 - - - - 41835 1450.00 40.72 23.75 -0.777810047970023 Down 0.667910447761194 CG31344 CG31344 - - - - 39301 2713.53 4.885 5.02 0.0393288019823867 Up 0.0695086514331 CG7368 CG7368, isoform C K09228|1|1e-22|108|mmu:22698|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding GO:0006909//phagocytosis 42877 2810.00 9.04 9.33 0.0455543084365713 Up 0.0960903447364945 CG6204 CG6204 K10742|1|4e-24|114|bta:540969|DNA replication ATP-dependent helicase Dna2 [EC:3.6.1.-] - GO:0004386//helicase activity;GO:0000166//nucleotide binding - 40862 2422.00 11.615 10.45 -0.152486211840563 Down 0.23609826971338 CG10055 CG10055 - - - - 46662 1669.45 6.915 6.64 -0.0585460098035692 Down 0.09731211200634 l(2)09851 lethal (2) 09851, isoform B K10752|1|2e-31|137|mdo:100018407|histone-binding protein RBBP4 - - - 326329 1169.00 260.915 262.255 0.00739039158320354 Up 0.0694095892220314 CG33199 CG33199, isoform B - - - - 33384 1216.00 0.16 0.43 1.4262647547021 Up 0.18663320565315 CG12674 CG12674, isoform B - - - - 19835232 6450.00 0.015 0.025 0.736965594166206 Up 0.047450799101836 33043 2334.00 6.405 6.68 0.0606495321324054 Up 0.09731211200634 cactin cactin - - - - 32637 5083.00 5.255 5.345 0.0244991837583121 Up 0.0573900409457139 mthl1 methuselah-like 1, isoform B K04599|1|0.0|1257|dme:Dmel_CG4521|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0010259//multicellular organismal aging 19836130 908.00 0.355 0.26 -0.44930740136359 Down 0.0921278562937525 39550 2305.87 7.73 8.53 0.142077327393443 Up 0.198652753929468 CG8783 CG8783, isoform C - - - - 35353 1150.00 13.93 12.395 -0.168436986514531 Down 0.27212389380531 CG9335 target of wit - - - - 36922 3410.00 1.055 1.02 -0.0486738467356894 Down 0.0483423590014529 CG6967 CG6967, isoform D K13983|1|2e-69|264|bfo:BRAFLDRAFT_215302|putative helicase MOV10L1 [EC:3.6.4.13] - - - 19836137 1106.00 0.2 0.385 0.944858445807539 Up 0.139908862765817 49168 1326.96 67.46 78.5 0.218660335648225 Up 0.4293356227711 l(2)37Cc lethal (2) 37Cc, isoform D K09655|1|4e-08|59.3|cfa:491067|beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-] GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0031967;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0031967;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0031967;GO:0043231//intracellular membrane-bounded organelle - GO:0009791//post-embryonic development;GO:0009791//post-embryonic development;GO:0009791//post-embryonic development 35365 1357.00 3.88 7.19 0.88993511825217 Up 0.534341566503764 CG9272 CG9272 K10773|1|0.0|748|dme:Dmel_CG9272|endonuclease III [EC:4.2.99.18] - GO:0003676//nucleic acid binding;GO:0051536//iron-sulfur cluster binding;GO:0004518//nuclease activity GO:0006281//DNA repair 38007 4452.18 5.21 6.24 0.26026265658374 Up 0.264463082816008 CG16778 jim lovell, isoform F K09237|1|6e-24|114|dme:Dmel_CG1856|Cys2His2 zinc finger developmental/cell cycle regulator, other - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0009629//response to gravity;GO:0009629//response to gravity;GO:0009629//response to gravity;GO:0009629//response to gravity 261616 1080.81 39.26 32.295 -0.281749352577781 Down 0.464799894333642 CG31778 CG31778, isoform B - - GO:0004866//endopeptidase inhibitor activity - 38593 2015.00 35.8 33.3 -0.104437410192994 Down 0.232135781270638 Srp54k signal recognition particle protein 54k K03106|1|0.0|957|dme:Dmel_CG4659|signal recognition particle subunit SRP54 GO:0030529//ribonucleoprotein complex GO:0042277//peptide binding;GO:0003723//RNA binding;GO:0032561//guanyl ribonucleotide binding;GO:0016462//pyrophosphatase activity GO:0007033//vacuole organization;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006914//autophagy 10178964 5470.38 685.95 845.655 0.301965790400985 Up 0.539030511161009 34923 950.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 CG18478 CG18478 K01312|1|3e-28|125|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09628|2|5e-27|121|xtr:595077|protease, serine 27 [EC:3.4.21.-];K09636|3|1e-26|120|dre:569688|transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-];K01324|4|3e-25|115|gga:422723|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36542 16672.50 54.08 52.415 -0.0451154137349451 Down 0.14631488574825 shot short stop, isoform Z K10382|1|0.0|2127|ecb:100056885|dystonin GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part;GO:0030427//site of polarized growth;GO:0005818//aster;GO:0070161;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development;GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0016198//axon choice point recognition;GO:0007420//brain development;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0035148//tube formation;GO:0035146;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007019//microtubule depolymerization;GO:0060541//respiratory system development 38412 3777.78 25.225 23.85 -0.0808650031008458 Down 0.183595297847048 CG11526 CG11526, isoform C - - - - 36266 964.00 0.605 0.6 -0.0119726416660766 Down 0.041044776119403 Damm death associated molecule related to Mch2 K04396|1|4e-17|88.6|gga:395477|caspase 6 [EC:3.4.22.59] GO:0044424//intracellular part GO:0004175//endopeptidase activity GO:0012502//induction of programmed cell death;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007435//salivary gland morphogenesis;GO:0019538//protein metabolic process 34315 1013.91 53.865 53.15 -0.0192784619673471 Down 0.0862171443666623 CG4598 CG4598, isoform B K13238|1|2e-145|514|dme:Dmel_CG4598|3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8] GO:0043231//intracellular membrane-bounded organelle GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds - 40720 4309.85 6.32 6.745 0.0938938847711647 Up 0.130167745344076 CG10979 CG10979, isoform B K09220|1|8e-07|56.6|cin:778824|IKAROS family zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 31313 1155.00 2.735 4.705 0.78265388993598 Up 0.442940166424515 CG16782 CG16782 - - - - 41091 1882.00 16.22 17.505 0.109993242211231 Up 0.21304979527143 beag beag K13109|1|0.0|742|dme:Dmel_CG18005|IK cytokine GO:0005681//spliceosomal complex - - 7354414 636.13 21.245 24.265 0.191753516450912 Up 0.34140140007925 CG42308 CG42308, isoform B - - - - 48440 2188.00 0.105 0.17 0.695145418471579 Up 0.0806696605468234 Kebab kinetochore and EB1 associated basic protein, isoform B - - - - 33542 1646.00 0.395 1.115 1.4971191517432 Up 0.316470743626998 CG15406 CG15406 K08145|1|3e-43|176|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8;K08144|5|2e-39|164|bta:510658|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6 GO:0031224//intrinsic to membrane - GO:0006810//transport 5740564 898.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 CG41020 CG41020 - - GO:0046872//metal ion binding - 41456 1564.12 43.825 59.02 0.429449829785107 Up 0.58502839783384 Tk tachykinin, isoform B - GO:0044421//extracellular region part GO:0005179//hormone activity;GO:0022857//transmembrane transporter activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0050896//response to stimulus 41420 4607.42 10.165 10.8 0.0874210972060986 Up 0.154735173689077 CG6923 CG6923, isoform D K10629|1|2e-09|65.5|gga:422382|E3 ubiquitin-protein ligase RNF128 [EC:6.3.2.19];K11980|3|7e-09|63.9|tad:TRIADDRAFT_28983|E3 ubiquitin-protein ligase RNF11 - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 40333 5669.18 6.505 4.435 -0.552614952416731 Down 0.423788138951261 Ac78C adenylyl cyclase 78C, isoform F K01768|1|0.0|3060|dme:Dmel_CG10564|adenylate cyclase [EC:4.6.1.1];K08048|2|4e-105|384|dre:100148976|adenylate cyclase 8 [EC:4.6.1.1] GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process 34429 943.00 16.845 17.235 0.0330208702455121 Up 0.0922599392418439 CG5343 CG5343 - GO:0005681//spliceosomal complex GO:0001071//nucleic acid binding transcription factor activity GO:0000377;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 326131 594.00 1.355 1.14 -0.24925902718913 Down 0.119072777704398 CG31275 CG31275 K10419|1|2e-07|55.1|bmy:Bm1_24930|dynein light chain roadblock-type GO:0005875//microtubule associated complex GO:0016887//ATPase activity GO:0007017//microtubule-based process 3772140 548.00 20.845 7.12 -1.54975222584199 Down 0.713346981904636 CG14246 CG14246, isoform C - - - - 246519 1699.00 0.205 0.225 0.134301091711591 Up 0.0491348566900013 CG30272 CG30272 K08193|1|2e-80|299|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|3|2e-76|286|nve:NEMVE_v1g228652|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - GO:0006810//transport 45906 2555.00 8.005 8.03 0.00449858500105758 Up 0.0427618544445912 mr morula K03349|1|0.0|1548|dme:Dmel_CG3060|anaphase-promoting complex subunit 2 GO:0000152//nuclear ubiquitin ligase complex GO:0019899//enzyme binding GO:0007049//cell cycle;GO:0051969;GO:0019941//modification-dependent protein catabolic process;GO:0008582//regulation of synaptic growth at neuromuscular junction 43428 5187.85 51.22 53.82 0.0714351380429489 Up 0.186600184916127 Pkc98E protein C kinase 98E, isoform D K06068|1|0.0|1113|dme:Dmel_CG1954|novel protein kinase C [EC:2.7.11.13] - GO:0043169//cation binding;GO:0008289//lipid binding;GO:0004697//protein kinase C activity;GO:0032559;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0004697//protein kinase C activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023033 43396 1236.00 2.565 3.06 0.254572827085598 Up 0.183925505217276 CG14061 aquarius K09628|1|1e-06|54.7|ecb:100068526|protease, serine 27 [EC:3.4.21.-];K01352|3|4e-06|52.8|ecb:100062497|granzyme A [EC:3.4.21.78] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40307 908.00 1.19 0.605 -0.975954526033349 Down 0.263043191124026 CG3288 CG3288, isoform B - - - - 36871 1298.00 0.765 0.235 -1.70279899101501 Down 0.277077004358737 CG15617 CG15617 - - - - 40843 2545.85 17.475 16.19 -0.110189469960233 Down 0.21304979527143 CG1104 CG1104, isoform C - - GO:0003824//catalytic activity - 32439 521.00 86.095 95.52 0.149873381613154 Up 0.340641923127724 CG9065 CG9065 K02260|1|8e-24|108|dme:Dmel_CG9065|cytochrome c oxidase subunit XVII assembly protein GO:0005740//mitochondrial envelope GO:0005507//copper ion binding GO:0000041//transition metal ion transport 38126 487.00 18.335 0.61 -4.90964721314878 Down 0.849029190331528 LysC lysozyme C K01185|1|7e-42|169|dme:Dmel_CG9111|lysozyme [EC:3.2.1.17];K01183|3|1e-40|164|dme:Dmel_CG9118|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 32776 843.00 31.16 42.86 0.459936616614878 Up 0.58502839783384 CG7772 CG7772 - - GO:0016836//hydro-lyase activity;GO:0046914//transition metal ion binding - 35000 1075.00 25.535 23.33 -0.130289751728217 Down 0.265618808611808 CG17904 CG17904 K03593|1|3e-37|155|hmg:100198387|ATP-binding protein involved in chromosome partitioning GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0031163 42870 600.00 22.38 22.345 -0.0022579915813842 Down 0.0434552899220711 mRpS24 mitochondrial ribosomal protein S24 - GO:0000314//organellar small ribosomal subunit;GO:0000315//organellar large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity - 8674001 1064.00 14.82 16.85 0.185203143763387 Up 0.309602430326245 CG42496 CG42496, isoform B K01598|1|3e-108|391|dme:Dmel_CG30290|phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] - - - 44887 2078.64 28.315 30.63 0.113378837111376 Up 0.243131686699247 mdy midway, isoform D K11155|1|0.0|1099|der:Dere_GG22776|diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.76] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0042981//regulation of apoptotic process;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage;GO:0042981//regulation of apoptotic process;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage;GO:0042981//regulation of apoptotic process;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage;GO:0042981//regulation of apoptotic process;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage 39740 1005.37 60.93 60.105 -0.0196677298653551 Down 0.0874058908994849 CG17029 CG17029, isoform B K01092|1|1e-162|572|dme:Dmel_CG17029|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] - GO:0004437//inositol or phosphatidylinositol phosphatase activity GO:0006796//phosphate-containing compound metabolic process 118436 3816.24 26.16 28.765 0.136951929386156 Up 0.285860520406815 Ranbp16 Ranbp16, isoform H K05270|1|7e-72|273|dvi:Dvir_GJ19199|gamma-aminobutyric acid (GABA) receptor, invertebrate GO:0005635//nuclear envelope;GO:0005635//nuclear envelope;GO:0005635//nuclear envelope;GO:0005635//nuclear envelope;GO:0005635//nuclear envelope GO:0003676//nucleic acid binding;GO:0022892;GO:0017016//Ras GTPase binding;GO:0003676//nucleic acid binding;GO:0022892;GO:0017016//Ras GTPase binding;GO:0003676//nucleic acid binding;GO:0022892;GO:0017016//Ras GTPase binding;GO:0003676//nucleic acid binding;GO:0022892;GO:0017016//Ras GTPase binding;GO:0003676//nucleic acid binding;GO:0022892;GO:0017016//Ras GTPase binding GO:0010468//regulation of gene expression;GO:0006605//protein targeting;GO:0010468//regulation of gene expression;GO:0006605//protein targeting;GO:0010468//regulation of gene expression;GO:0006605//protein targeting;GO:0010468//regulation of gene expression;GO:0006605//protein targeting;GO:0010468//regulation of gene expression;GO:0006605//protein targeting 34646 1033.00 15.34 10.17 -0.592978803645433 Down 0.55445119535068 crok crooked - - - - 3346222 638.00 2.19 0.915 -1.25908722131713 Down 0.399220710606261 lectin-37Da lectin-37Da, isoform B K06561|1|1e-08|59.7|mmu:246278|CD207 antigen;K06560|2|2e-08|58.5|cin:100186027|mannose receptor, C type;K06468|4|3e-08|58.2|ssc:100037942|Fc receptor, IgE, low affinity II - GO:0048029//monosaccharide binding;GO:0004871//signal transducer activity;GO:0051635//bacterial cell surface binding;GO:0048029//monosaccharide binding;GO:0004871//signal transducer activity;GO:0051635//bacterial cell surface binding GO:0019731//antibacterial humoral response;GO:0019731//antibacterial humoral response 10178841 622.00 0.24 0.725 1.59494658929378 Up 0.261623299432043 8674014 233.00 3.03 3.23 0.0922163712209742 Up 0.0923590014529124 Sfp79B seminal fluid protein 79 - - - - 41838 724.75 19.275 22.515 0.224155617539448 Up 0.368643508123101 mRpS10 mitochondrial ribosomal protein S10, isoform B - - - - 19835537 966.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 40827 935.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 zen2 zerknullt-related, isoform B K09311|1|4e-110|397|dme:Dmel_CG1048|Antp family, other;K09304|5|1e-15|84.0|phu:Phum_PHUM266770|homeobox protein HoxA/B/C/D4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007447//imaginal disc pattern formation;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007447//imaginal disc pattern formation 19836136 1101.00 0.045 0.29 2.68805599368526 Up 0.196737551182142 42437 2813.00 74.78 73.775 -0.0195204555387992 Down 0.0881323471139876 CG16953 CG16953 - - - - 35254 1366.00 0.14 0.25 0.836501267717121 Up 0.107119270902127 msb1l msb1l - - - - 5740624 927.00 7.615 8.485 0.156070623055371 Up 0.214040417382116 l(3)72Do heat shock protein cognate 20 K04082|1|4e-124|444|dme:Dmel_CG34246|molecular chaperone HscB GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006355//regulation of transcription, DNA-dependent 44021 1357.00 27.535 29.23 0.0861832206551744 Up 0.203803988905032 nmd no mitochondrial derivative, isoform C K13254|1|1e-51|203|dre:405851|spastin [EC:3.6.4.3] GO:0031966//mitochondrial membrane GO:0016462//pyrophosphatase activity;GO:0032559 GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007033//vacuole organization;GO:0007281//germ cell development;GO:0006914//autophagy 35208 664.14 25.3 12.345 -1.03521054843889 Down 0.680458327829877 CG13086 CG13086, isoform C - - - - 3771985 4831.17 20.78 34.98 0.751334635017441 Up 0.656485272751288 Pif1B PFTAIRE-interacting factor 1B, isoform D K09291|1|3e-08|62.4|cin:100185005|nucleoprotein TPR;K11499|2|5e-08|61.6|cfa:610263|centromere protein F;K10382|3|2e-07|60.1|hsa:667|dystonin;K04648|4|3e-07|59.3|dre:407638|dynactin 1;K11498|5|6e-07|58.2|dpo:Dpse_GA25699|centromeric protein E - GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005488//binding - 33443 618.50 243.365 262.835 0.11103570357633 Up 0.282591467441553 CG3214 CG3214, isoform C K11352|1|2e-84|311|dme:Dmel_CG3214|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 12 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 12797878 2447.00 3.315 3.47 0.0659267924656729 Up 0.0780610223220182 36179 504.00 0.095 0.115 0.275634442613427 Up 0.0530973451327434 CG13227 CG13227 - - - - 45401 331.00 370.815 383.46 0.0483764889806335 Up 0.160645885616167 ox oxen K00419|1|1e-24|111|dsi:Dsim_GD25813|ubiquinol-cytochrome c reductase subunit 9 [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity GO:0022904//respiratory electron transport chain 41096 4147.27 11.57 13.145 0.184125277510556 Up 0.279586580372474 ird1 immune response deficient 1, isoform C K08333|1|0.0|2580|dsi:Dsim_GD20813|phosphoinositide-3-kinase, regulatory subunit 4, p150 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0009267//cellular response to starvation;GO:0002700;GO:0006914//autophagy;GO:0006464//cellular protein modification process;GO:0009267//cellular response to starvation;GO:0002700;GO:0006914//autophagy;GO:0006464//cellular protein modification process 33604 10113.21 4.755 3.415 -0.477559762570473 Down 0.346684718002906 CG3921 CG3921, isoform C K00280|1|2e-12|77.0|cin:100179074| [EC:1.4.3.-] GO:0044464//cell part GO:0004888//transmembrane signaling receptor activity - 19834835 323.00 5.55 3.915 -0.503475463946428 Down 0.378813895126139 8674058 227.00 43.975 41.48 -0.0842676835460976 Down 0.201426495839387 CG42481 CG42481, isoform B - - - - 36675 1834.00 22.825 29.705 0.380090928327577 Up 0.523180557390041 CG7639 CG7639 - GO:0016020//membrane - - 39882 367.00 30.455 27 -0.173719697145483 Down 0.331065909391098 CG9669 CG9669, isoform B - GO:0016020//membrane - - 318148 889.00 0.09 0.105 0.222392421336448 Up 0.0521727644961036 Rab9E Rab at 9E K07976|1|1e-113|408|dme:Dmel_CG32673|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 39049 5265.70 46.44 52.425 0.174886984118388 Up 0.354345528992207 bol boule, isoform G K12741|1|6e-08|58.9|cin:100182977|heterogeneous nuclear ribonucleoprotein A1/A3;K13195|2|1e-07|57.8|bfo:BRAFLDRAFT_71461|cold-inducible RNA-binding protein;K12894|4|2e-06|54.3|mdo:100013568|heterogeneous nuclear ribonucleoprotein A0 GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0006412//translation;GO:0048610//cellular process involved in reproduction;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0040020//regulation of meiosis;GO:0006412//translation;GO:0048610//cellular process involved in reproduction;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0040020//regulation of meiosis;GO:0006412//translation;GO:0048610//cellular process involved in reproduction;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0040020//regulation of meiosis;GO:0006412//translation;GO:0048610//cellular process involved in reproduction;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0040020//regulation of meiosis;GO:0006412//translation;GO:0048610//cellular process involved in reproduction;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0040020//regulation of meiosis 35641 2312.00 0.2 0.405 1.01792190799726 Up 0.151334037775723 CG11060 CG11060 - - - - 5740646 1030.00 0.145 0.205 0.499571009490512 Up 0.0789525822216352 32301 7583.00 8.385 9.54 0.186178482441165 Up 0.254391758024039 Set2 Set2, isoform B K11423|1|0.0|3632|dme:Dmel_CG1716|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0005515//protein binding GO:0034968//histone lysine methylation;GO:0002164//larval development;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0007444//imaginal disc development;GO:0006351//transcription, DNA-dependent;GO:0034968//histone lysine methylation;GO:0002164//larval development;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0007444//imaginal disc development;GO:0006351//transcription, DNA-dependent 40152 3070.00 12.59 12.105 -0.05667520372008 Down 0.121879540351341 trpml transient receptor potential cation channel, mucolipin ortholog K04994|1|2e-107|390|mmu:171166|mucolipin 3 - GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity GO:0006022 33847 4284.68 51.775 25.225 -1.03740137911415 Down 0.711861048738608 ade2 adenosine 2, isoform C K01952|1|0.0|2624|dme:Dmel_CG9127|phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] - GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0006188//IMP biosynthetic process;GO:0006188//IMP biosynthetic process;GO:0006188//IMP biosynthetic process 33869 855.00 1.095 0.615 -0.832272554261933 Down 0.231409325056135 CG13989 CG13989 - - - - 41481 1448.00 0.79 1.08 0.451106753986365 Up 0.158631620657773 CG10014 CG10014 - - - - 246425 1683.00 5.4 2.41 -1.16392626082087 Down 0.538997490423986 CG30059 CG30059 K01137|1|0.0|1037|dme:Dmel_CG30059|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14] GO:0000323//lytic vacuole GO:0008484//sulfuric ester hydrolase activity GO:0006041//glucosamine metabolic process;GO:0006022 42380 2980.70 15.31 15.615 0.0284582865207857 Up 0.0874389116365077 Hs6st heparan sulfate 6-O-sulfotransferase, isoform B K02514|1|0.0|898|dme:Dmel_CG4451|heparan sulfate 6-O-sulfotransferase HS6ST1 [EC:2.8.2.-];K08103|2|3e-97|356|dre:569353|heparan sulfate 6-O-sulfotransferase HS6ST3 [EC:2.8.2.-] GO:0031224//intrinsic to membrane GO:0016782//transferase activity, transferring sulfur-containing groups GO:0005975//carbohydrate metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060446//branching involved in open tracheal system development 38050 6670.94 29.085 35.575 0.290588452585896 Up 0.468267071721041 RhoGEF3 Rho guanine nucleotide exchange factor 3, isoform M K05769|1|5e-47|190|rno:301334|Rho guanine nucleotide exchange factor 4 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089 GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 32891 2489.00 0.02 0.24 3.58496250072116 Up 0.202681283846255 CG14190 CG14190 - - - - 31626 1218.00 0.065 0.11 0.758991900496205 Up 0.0760797781006472 CG12796 CG12796 K04141|1|3e-29|129|dre:557194|adrenergic receptor beta-1;K04136|2|3e-28|125|tgu:100218481|adrenergic receptor alpha-1B - - - 43577 1279.00 7.475 8.37 0.163154043464876 Up 0.217870822876767 spn-A spindle A, isoform B K04482|1|1e-166|585|dme:Dmel_CG7948|DNA repair protein RAD51 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042623//ATPase activity, coupled;GO:0003677//DNA binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003677//DNA binding;GO:0032559 GO:0009948//anterior/posterior axis specification;GO:0007050//cell cycle arrest;GO:0065001//specification of axis polarity;GO:0010038//response to metal ion;GO:0007126//meiosis;GO:0051276//chromosome organization;GO:0000724//double-strand break repair via homologous recombination;GO:0007292//female gamete generation;GO:0003006//developmental process involved in reproduction;GO:0006403//RNA localization;GO:0010033//response to organic substance;GO:0009948//anterior/posterior axis specification;GO:0007050//cell cycle arrest;GO:0065001//specification of axis polarity;GO:0010038//response to metal ion;GO:0007126//meiosis;GO:0051276//chromosome organization;GO:0000724//double-strand break repair via homologous recombination;GO:0007292//female gamete generation;GO:0003006//developmental process involved in reproduction;GO:0006403//RNA localization;GO:0010033//response to organic substance 38780 2069.00 0.225 0.065 -1.79141337818858 Down 0.144102496367719 BBS1 Bardet-Biedl syndrome 1 ortholog K01277|1|4e-66|253|ecb:100058485|dipeptidyl-peptidase III [EC:3.4.14.4] - - GO:0007275//multicellular organismal development;GO:0010927;GO:0002009//morphogenesis of an epithelium 38938 960.00 8.285 12.595 0.604277519512789 Up 0.534473649451856 CG13670 CG13670 - - GO:0005198//structural molecule activity - 50391 3628.58 3.525 3.125 -0.173767067736706 Down 0.151664245145952 Grip glutamate receptor binding protein, isoform C K12076|1|4e-13|77.8|dre:497648|disks large protein 1 GO:0045202//synapse;GO:0033267//axon part;GO:0016023//cytoplasmic membrane-bounded vesicle GO:0005515//protein binding GO:0043062//extracellular structure organization;GO:0006606//protein import into nucleus;GO:0009887//organ morphogenesis 19834837 1300.00 1.945 1.815 -0.0998006069904412 Down 0.0794478932769779 31404 5574.65 9.05 10.225 0.176111145858544 Up 0.252641658961828 Pp2C1 protein phosphatase 2C, isoform B K01090|1|0.0|1733|dme:Dmel_CG2984|protein phosphatase [EC:3.1.3.16];K03364|2|0.0|689|dse:Dsec_GM12670|cell division cycle 20-like protein 1, cofactor of APC complex;K10147|3|9e-70|266|xla:443988|protein phosphatase 1D (formerly 2C) [EC:3.1.3.16] GO:0043234//protein complex GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 34118 3240.00 7.4 14.24 0.944351970450086 Up 0.625049531105534 CG8419 CG8419 K12021|1|0.0|1588|dme:Dmel_CG8419|tripartite motif-containing protein 45 GO:0044464//cell part GO:0046914//transition metal ion binding - 34674 1916.00 29.775 25.915 -0.200314114366777 Down 0.365473517368908 CG5525 CG5525 K09496|1|0.0|1015|dme:Dmel_CG5525|T-complex protein 1 subunit delta GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0044267//cellular protein metabolic process 37100 361.00 297.705 375.67 0.335582458759371 Up 0.567131158367455 IM1 immune induced molecule 1 - - - - 38797 996.00 0.045 0.055 0.289506617194985 Up 0.0467903843613789 mei-P22 meiotic P22 - - - GO:0007127//meiosis I;GO:0006310//DNA recombination 31049 590.00 0.345 0.385 0.158262083916732 Up 0.0596684718002906 CG14631 CG14631 - - - - 31064 1413.00 0.96 0.585 -0.714597781137752 Down 0.197827235503896 CG14626 CG14626 - - - - 19835830 955.00 0.085 0.265 1.64045761331286 Up 0.152423722097477 53554 3851.73 20.185 19.31 -0.0639354225298598 Down 0.145093118478404 krz kurtz, isoform B K04439|1|0.0|773|dme:Dmel_CG1487|beta-arrestin - - GO:0050877//neurological system process;GO:0050896//response to stimulus;GO:0008593//regulation of Notch signaling pathway;GO:0023060 4379815 1020.33 1.235 1.14 -0.115477217419936 Down 0.0725465592392022 19836159 974.00 0.085 0.18 1.08246216019197 Up 0.103024699511293 41738 2146.57 57.265 46.36 -0.304773076055034 Down 0.501915202747325 CG12207 CG12207, isoform G - - - - 34619 1882.00 48.03 49.29 0.0373591724338174 Up 0.126601505745608 CG6766 CG6766 K14008|1|0.0|1021|dme:Dmel_CG6766|endoplasmic reticulum lectin 1 - GO:0005488//binding - 12798000 923.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 37902 1515.00 1.6 1.895 0.24412594328373 Up 0.139776779817726 CG3492 CG3492 K12739|1|2e-07|57.4|gga:421764|peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8] - GO:0005515//protein binding;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 34796 970.00 10.275 9.83 -0.0638750722284648 Down 0.119105798441421 RpII33 RNA polymerase II 33kD subunit K03011|1|2e-159|561|dme:Dmel_CG7885|DNA-directed RNA polymerase II subunit C GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0015630//microtubule cytoskeleton GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0006351//transcription, DNA-dependent 53542 1268.25 10.86 17.96 0.725763246936786 Up 0.60669000132083 lectin-28C lectin-28C, isoform C K05328|1|2e-10|65.9|dan:Dana_GF15877|transient receptor potential cation channel subfamily C, invertebrate;K03991|2|8e-09|60.8|dre:566971|mannose-binding lectin;K10068|3|1e-08|60.5|oaa:100075971|surfactant, pulmonary-associated protein D;K06560|4|2e-08|59.3|mdo:100026773|mannose receptor, C type - - - 32475 1299.75 28.925 30.035 0.0543277045316177 Up 0.139116365077269 CG6299 CG6299, isoform E K08051|1|4e-78|293|dpo:Dpse_GA19499|pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005319//lipid transporter activity;GO:0008289//lipid binding;GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0006869//lipid transport;GO:0006869//lipid transport 37716 1399.00 0.085 0.035 -1.28010791919273 Down 0.0799432043323207 Or59c odorant receptor 59c K08471|1|0.0|837|dme:Dmel_CG17226|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 37918 725.49 142.4 138.325 -0.0418872225235733 Down 0.135550125478801 CG13585 CG13585, isoform D - - - - 12797947 874.00 0.94 1.785 0.925191412351462 Up 0.315744287412495 CG43278 CG43278, isoform B - - - - 35793 1558.00 33.835 35.585 0.072752847420238 Up 0.178146876238278 RagC Ras-related GTP binding C/D ortholog - GO:0043231//intracellular membrane-bounded organelle GO:0032561//guanyl ribonucleotide binding - 38453 1470.00 0.135 0.335 1.3112016882943 Up 0.155923920221899 Gr63a gustatory receptor 63a K08471|1|0.0|882|dme:Dmel_CG14979|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0010035//response to inorganic substance;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0009593//detection of chemical stimulus 34121 817.64 32.26 32.69 0.0191029386116229 Up 0.0812310130762119 CG8372 CG8372, isoform B - - - - 326179 1199.26 0.945 1.815 0.941583313774678 Up 0.3195086514331 CG31952 CG31952, isoform B - - - - 19834842 411.00 0.31 0.01 -4.95419631038687 Down 0.276482631092326 19834760 1725.07 80.715 74.305 -0.119377514212948 Down 0.285497292299564 - CG45076, isoform I - - - - 32768 896.99 13.145 15.325 0.221372931960098 Up 0.334136837934223 CG6762 CG6762, isoform D K12260|1|7e-88|323|dme:Dmel_CG6762|sulfiredoxin [EC:1.8.98.2] - GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0003676//nucleic acid binding;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0003676//nucleic acid binding;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0003676//nucleic acid binding;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0003676//nucleic acid binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 42993 2834.00 11.68 13.105 0.1660770794484 Up 0.266015057456082 Hr96 hormone receptor-like in 96 K14035|1|0.0|1385|dme:Dmel_CG11783|nuclear receptor subfamily 1 group I GO:0043231//intracellular membrane-bounded organelle GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 38750 1454.48 36.185 33.225 -0.123122572106317 Down 0.266444327037379 CG10103 CG10103, isoform F - - - - 35913 2417.68 8.695 9.405 0.113241916216608 Up 0.17319376568485 ana anachronism, isoform C - - GO:0005102//receptor binding;GO:0005102//receptor binding GO:0007405//neuroblast proliferation;GO:0007405//neuroblast proliferation 12798331 746.00 68.565 93.95 0.454420841982227 Up 0.608803328490292 CG43324 CG43324 - - - - 4379879 306.00 5.935 19.495 1.71578421975573 Up 0.720611544049663 Acp54A1 accessory gland protein 54A1 - - - - 31837 875.00 24.185 25.555 0.079493053554347 Up 0.183298111213842 CG6999 CG6999 - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0000380//alternative mRNA splicing, via spliceosome 42102 887.00 0.225 0.2 -0.169925001442312 Down 0.0510500594373266 CG14330 CG14330 - - - - 39020 1531.00 48.575 37.18 -0.385687225553225 Down 0.55560692114648 GNBP3 Gram-negative bacteria binding protein 3 - - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0051635//bacterial cell surface binding;GO:0004872//receptor activity GO:0044238//primary metabolic process;GO:0051707//response to other organism;GO:0006950//response to stress 45247 1351.96 177.415 195.09 0.137011838514332 Up 0.334268920882314 VhaPPA1-1 vacuolar H[+] ATPase PPA1 subunit 1, isoform B K03661|1|9e-100|363|dya:Dyak_GE26419|V-type H+-transporting ATPase 21kDa proteolipid subunit [EC:3.6.3.14] GO:0031224//intrinsic to membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0000278//mitotic cell cycle;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 43927 2043.61 10.295 8.115 -0.343280830084283 Down 0.389446572447497 fal falten, isoform C - - - GO:0048598//embryonic morphogenesis;GO:0048598//embryonic morphogenesis 42300 3258.00 4.355 4.74 0.122214340299394 Up 0.135385021793686 sqz squeeze K09228|1|2e-35|151|rno:308420|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0014016//neuroblast differentiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006928//cellular component movement 40905 1848.09 5.99 6.255 0.0624538813770342 Up 0.09731211200634 alpha-Est5 alpha-Esterase-5, isoform B K01044|1|0.0|1125|dme:Dmel_CG1089|carboxylesterase [EC:3.1.1.1];K03927|2|0.0|944|dan:Dana_GF17295|carboxylesterase type B [EC:3.1.1.1] - GO:0016788//hydrolase activity, acting on ester bonds - 36703 5177.61 9.725 10.49 0.109244522703713 Up 0.178675208030643 unc-5 unc-5, isoform B K07521|1|0.0|2010|dme:Dmel_CG8166|netrin receptor unc-5 - GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007431//salivary gland development;GO:0016477//cell migration;GO:0007411//axon guidance;GO:0023060 64875 5154.63 5.415 5.655 0.0625656863814933 Up 0.0920948355567296 disco-r disco-related, isoform D - - - - 38760 2275.00 21.18 19.59 -0.11258519172475 Down 0.224342887333245 sgl sugarless K00012|1|0.0|949|dsi:Dsim_GD13103|UDPglucose 6-dehydrogenase [EC:1.1.1.22] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0048037//cofactor binding GO:0007635//chemosensory behavior;GO:0006024//glycosaminoglycan biosynthetic process;GO:0002118//aggressive behavior;GO:0007420//brain development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0060446//branching involved in open tracheal system development;GO:0001707//mesoderm formation 35764 1687.00 0.345 0.245 -0.493814612662961 Down 0.0962884691586316 Hey Hairy/E(spl)-related with YRPW motif K09091|1|2e-116|419|dme:Dmel_CG11194|hairy and enhancer of split related with YRPW motif GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016874//ligase activity;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0008593//regulation of Notch signaling pathway;GO:0006351//transcription, DNA-dependent 33810 2535.73 1.615 2.14 0.406076631707222 Up 0.211927090212654 CG11034 CG11034, isoform D K01278|1|0.0|1526|dme:Dmel_CG11034|dipeptidyl-peptidase 4 [EC:3.4.14.5] GO:0044464//cell part GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 12798528 370.28 22.635 36.335 0.682804599736443 Up 0.641328754457799 CG43222 CG43222, isoform B - - - - 40475 1794.00 0.3 0.655 1.12653240592893 Up 0.211299696209219 Trxr-2 thioredoxin reductase 2 K00384|1|0.0|1014|dme:Dmel_CG11401|thioredoxin reductase (NADPH) [EC:1.8.1.9] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0042802//identical protein binding;GO:0030554//adenyl nucleotide binding;GO:0016209//antioxidant activity;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0010259//multicellular organismal aging;GO:0033554//cellular response to stress;GO:0008152//metabolic process;GO:0019725//cellular homeostasis 318235 865.00 0.055 0.11 1 Up 0.0856557918372738 CG32829 CG32829 - - - - 36992 1275.56 85.89 80.3 -0.0970901833158323 Down 0.250297186633206 Rab4 Rab4, isoform B K07881|1|1e-117|423|der:Dere_GG21802|Ras-related protein Rab-14;K07976|2|1e-117|423|dpo:Dpse_GA18527|Rab family, other;K07880|4|8e-92|337|dre:445498|Ras-related protein Rab-4B - - - 12798338 416.00 1.11 0.685 -0.696383783389579 Down 0.207073041870295 CG43069 CG43069 - - - - 40424 3611.78 26.59 28.17 0.083275786517263 Up 0.187854972922996 Syn1 Syntrophin-like 1, isoform E K12076|1|1e-09|66.2|gga:424890|disks large protein 1 GO:0016010//dystrophin-associated glycoprotein complex;GO:0016010//dystrophin-associated glycoprotein complex GO:0005515//protein binding;GO:0005515//protein binding - 59241 1170.00 0.265 0.19 -0.479992941119614 Down 0.088264430062079 CG18530 CG18530 K01046|1|2e-61|236|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|3|3e-58|225|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|4|4e-53|208|xla:734759|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 319025 2487.00 5.615 5.38 -0.0616798498439768 Down 0.09047681944261 CG31915 CG31915 K11703|1|0.0|1151|dme:Dmel_CG31915|collagen beta-1,O-galactosyltransferase [EC:2.4.1.50] - GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016740//transferase activity GO:0008610//lipid biosynthetic process;GO:0006041//glucosamine metabolic process 32245 7159.86 48.71 63.18 0.375249953906425 Up 0.56151763307357 fne found in neurons, isoform J K13208|1|0.0|658|dme:Dmel_CG4396|ELAV like protein 2/3/4 - GO:0003723//RNA binding;GO:0003723//RNA binding - 37267 531.83 521.76 386.585 -0.432600686004875 Down 0.619039756967376 Obp56e Odorant-binding protein 56e, isoform B - - - - 19835182 1326.00 0.06 0.07 0.222392421336448 Up 0.0461960110949676 19835219 455.00 0.095 0.13 0.452512204697507 Up 0.067956676793026 32221 2330.52 213.24 218.79 0.0370687127212068 Up 0.136441685378418 CkIalpha casein kinase ialpha, isoform G K02218|1|0.0|694|dme:Dmel_CG2028|casein kinase 1 [EC:2.7.11.1];K08957|4|5e-149|528|tca:662101|casein kinase 1, alpha [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0008589//regulation of smoothened signaling pathway;GO:0006508//proteolysis;GO:0009057//macromolecule catabolic process;GO:0006464//cellular protein modification process;GO:0006259//DNA metabolic process;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0008589//regulation of smoothened signaling pathway;GO:0006508//proteolysis;GO:0009057//macromolecule catabolic process;GO:0006464//cellular protein modification process;GO:0006259//DNA metabolic process;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0008589//regulation of smoothened signaling pathway;GO:0006508//proteolysis;GO:0009057//macromolecule catabolic process;GO:0006464//cellular protein modification process;GO:0006259//DNA metabolic process;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0008589//regulation of smoothened signaling pathway;GO:0006508//proteolysis;GO:0009057//macromolecule catabolic process;GO:0006464//cellular protein modification process 31791 4089.00 61.69 99.78 0.693714023077901 Up 0.677651565182935 PIP82 PIP82 - - - - 326253 1056.12 8.755 5.32 -0.718680932932368 Down 0.522090873068287 CG33098 CG33098, isoform F K12759|1|5e-22|104|ame:550973|myosin regulatory light chain, invertebrate - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - 8673987 168.00 4.035 3.95 -0.0307160202133153 Down 0.0602958658037247 Sfp96F seminal fluid protein 96F - - - - 33455 3248.00 9.755 11.145 0.192182838650726 Up 0.273741909919429 CG31690 CG31690 K09667|1|3e-18|94.7|dre:337685|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - - - 35962 759.00 0.44 0.255 -0.787006276665802 Down 0.135318980319641 CG8800 CG8800 K10411|1|3e-103|374|dya:Dyak_GE22335|dynein light chain 1, axonemal - GO:0005488//binding - 3771792 529.00 0.01 0.01 0 - 0.0382380134724607 His3:CG33830 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 34091 1792.00 26.235 19.56 -0.423586419690575 Down 0.535365209351473 Spn28Dc serpin 28Dc K13963|1|1e-34|147|dre:494155|serpin B - GO:0004866//endopeptidase inhibitor activity - 38766 2412.00 0.02 0.035 0.807354922057604 Up 0.0552767137762515 bin biniou K09399|1|1e-29|131|mmu:14238|forkhead box protein F GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0048333//mesodermal cell differentiation;GO:0010551;GO:0007431//salivary gland development 50446 409.00 208.235 93.3 -1.15826359004932 Down 0.745311055342755 CG16978 CG16978 - - - - 2768883 2310.33 10.4 0.07 -7.21501289097085 Down 0.881422533350944 Sdic2 Sperm-specific dynein intermediate chain 2, isoform C K10415|1|0.0|1039|dme:Dmel_CG33497|dynein intermediate chain, cytosolic GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0045502//dynein binding GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport 37345 2621.81 4.555 10.375 1.1875883773196 Up 0.627261920486065 exu exuperantia, isoform D - GO:0005681//spliceosomal complex - GO:0006810//transport;GO:0000377;GO:0019094//pole plasm mRNA localization;GO:0044087;GO:0045450//bicoid mRNA localization;GO:0048232//male gamete generation 37359 1294.00 0.095 0.105 0.144389909335175 Up 0.0448421608770308 CG15227 CG15227 K01672|1|9e-30|130|dpo:Dpse_GA21631|carbonic anhydrase [EC:4.2.1.1] - - - 318632 1677.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 Ir94f ionotropic receptor 94f - - - - 3772266 143.00 0.435 0.01 -5.44294349584873 Down 0.33109893012812 38304 1018.00 5.975 5.51 -0.116886394296953 Down 0.148064984810461 CG15877 CG15877 K04456|1|4e-07|55.5|tca:656423|RAC serine/threonine-protein kinase [EC:2.7.11.1] - - - 5740740 1008.00 90.46 134.28 0.569892541066139 Up 0.65721172896579 43662 3436.91 352.02 260.05 -0.436868359908958 Down 0.621945581825386 Sap-r Saposin-related, isoform B K12382|1|0.0|1884|dme:Dmel_CG12070|saposin GO:0000323//lytic vacuole;GO:0000323//lytic vacuole - GO:0050658//RNA transport;GO:0006643//membrane lipid metabolic process;GO:0050658//RNA transport;GO:0006643//membrane lipid metabolic process 39939 3462.45 17.68 18.55 0.0693009121167341 Up 0.153711530841368 blot bloated tubules, isoform E K05047|1|2e-11|72.0|ssc:431671|solute carrier family 6 (neurotransmitter transporter) member 14;K05038|2|3e-11|71.2|cin:100185022|solute carrier family 6 (neurotransmitter transporter, glycine) member 5;K05034|4|7e-11|70.1|gga:415960|solute carrier family 6 (neurotransmitter transporter, GABA) member 1 GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0048729//tissue morphogenesis;GO:0006810//transport;GO:0048729//tissue morphogenesis;GO:0006810//transport;GO:0048729//tissue morphogenesis;GO:0006810//transport;GO:0048729//tissue morphogenesis;GO:0006810//transport 35688 830.00 364.43 288.185 -0.338646481832449 Down 0.566966054682341 Cyt-b5 cytochrome b5, isoform B K10595|1|5e-13|74.7|bfo:BRAFLDRAFT_73255|E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19];K00326|2|5e-11|68.2|dre:553685|cytochrome-b5 reductase [EC:1.6.2.2];K10226|4|2e-10|65.9|ssc:444997|fatty acid desaturase 2 (delta-6 desaturase) [EC:1.14.19.-] GO:0042598;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0042598;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part GO:0005506//iron ion binding;GO:0005506//iron ion binding GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy 8674021 1420.00 6.575 6.065 -0.116483249059155 Down 0.154933298111214 CG42503 CG42503 - GO:0044444//cytoplasmic part GO:0003824//catalytic activity GO:0009108//coenzyme biosynthetic process 5740727 549.00 47.045 62.525 0.410391752694077 Up 0.57657508915599 43344 2491.00 9.295 10.045 0.11195079381381 Up 0.177156254127592 CG5003 CG5003 - - - - 38467 584.27 108.525 68.935 -0.654718856672631 Down 0.671839915466913 CG14984 CG14984, isoform C - - - - 5740660 448.00 1.115 1.46 0.388924658959713 Up 0.169231277242108 CG12828 CG12828 - - - - 36434 511.00 0.085 0.63 2.88981708224958 Up 0.30653150178312 CG13324 CG13324 - - - - 40057 741.00 2.985 2.795 -0.0948826484216151 Down 0.0906419231277242 NijB ninjurin B - GO:0031224//intrinsic to membrane - GO:0009987//cellular process;GO:0009888//tissue development 3355107 892.16 148.07 157.545 0.0894845980216129 Up 0.238772949412231 Tim17b Tim17b, isoform B K10836|1|4e-53|208|dme:Dmel_CG15257|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0022892 GO:0006810//transport 40051 1149.00 4.12 3.695 -0.157069973037067 Down 0.153018095363889 CG14074 CG14074 - - - - 36428 4085.94 14.425 19.645 0.445590848925842 Up 0.524468366133932 Mdr49 multi drug resistance 49, isoform B K05658|1|0.0|1730|dwi:Dwil_GK20875|ATP-binding cassette, subfamily B (MDR/TAP), member 1 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015405;GO:0016887//ATPase activity;GO:0032559;GO:0015405;GO:0016887//ATPase activity;GO:0032559 GO:0007276//gamete generation;GO:0006950//response to stress;GO:0006810//transport;GO:0007276//gamete generation;GO:0006950//response to stress;GO:0006810//transport 43251 1085.00 2.27 1.305 -0.798642490721031 Down 0.325782591467442 CG6277 CG6277 K01046|1|2e-119|428|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|1|2e-119|428|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32];K01059|4|7e-40|164|dpo:Dpse_GA18274|lipoprotein lipase [EC:3.1.1.34] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 39569 3062.14 8.25 9.335 0.178255903093024 Up 0.244716682076344 Sox21b Sox21b, isoform C K09267|1|2e-101|370|dan:Dana_GF25205|transcription factor SOX1/2/3/14/21 (SOX group B) GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding - 43475 2120.47 26.02 17.685 -0.557094743016877 Down 0.59232598071589 CG2010 CG2010, isoform C K10268|1|2e-13|77.8|dgr:Dgri_GH20493|F-box and leucine-rich repeat protein 2/20 - - - 43671 2153.00 38.77 48.115 0.31154599366772 Up 0.502278430854577 Aph-4 alkaline phosphatase 4, isoform B K01077|1|0.0|1088|dme:Dmel_CG1462|alkaline phosphatase [EC:3.1.3.1] GO:0031225//anchored to membrane;GO:0031225//anchored to membrane GO:0016791//phosphatase activity;GO:0016791//phosphatase activity GO:0048731;GO:0042044//fluid transport;GO:0048731;GO:0042044//fluid transport 36478 1654.39 0.21 0.79 1.91146332539834 Up 0.293884559503368 CG17047 CG17047, isoform B - - - - 34610 872.05 6.3 5.08 -0.310523331615113 Down 0.303625676925109 dgt2 dim gamma-tubulin 2, isoform B - GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization 40404 674.00 25.465 21.865 -0.219892368816326 Down 0.376799630167745 ORMDL ORMDL K12667|1|1e-20|99.4|smm:Smp_144800|oligosaccharyltransferase complex subunit delta (ribophorin II) GO:0031224//intrinsic to membrane - - 39115 836.00 521.02 947.235 0.862383635817702 Up 0.72219653942676 CG3088 CG3088 K01310|1|8e-64|243|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|4e-57|221|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42004 470.00 22.365 23.85 0.0927465078882752 Up 0.197728173292828 CG14898 CG14898 - - - - 36466 2159.00 16.345 18.69 0.193417191977892 Up 0.322084268920882 CG4679 CG4679 - - - - 246578 888.00 0.05 0.16 1.67807190511264 Up 0.117784968960507 CG30379 CG30379 K06890|1|1e-41|169|dpe:Dper_GL17451| GO:0008328//ionotropic glutamate receptor complex - - 40890 3262.00 0.31 0.435 0.488747185461853 Up 0.108241975960903 MstProx MstProx K10160|1|1e-17|92.8|dre:795671|toll-like receptor 4;K05404|3|5e-17|90.5|gga:418638|toll-like receptor 7 GO:0031224//intrinsic to membrane GO:0004872//receptor activity GO:0006952//defense response;GO:0023060 37292 590.35 1151.895 1130.735 -0.0267483574199262 Down 0.117388720116233 RpS18 ribosomal protein S18, isoform B K02964|1|6e-71|266|dya:Dyak_GE12097|small subunit ribosomal protein S18e - - - 32055 2302.91 20.14 15.31 -0.395589400506997 Down 0.499867917051909 Lint-1 l(3)mbt interacting protein 1, isoform E K03538|1|6e-07|56.6|cqu:CpipJ_CPIJ000727|ribonuclease P subunit P29 [EC:3.1.26.5] - GO:0005488//binding - 19836255 544.00 0.155 0.51 1.71822903158462 Up 0.226390173028662 37123 1757.00 13.015 12.92 -0.0105692417101875 Down 0.0547483819838859 Prp19 Prp19 K10599|1|0.0|936|dme:Dmel_CG5519|pre-mRNA-processing factor 19 [EC:6.3.2.19] - - - 36091 979.94 3.34 5.315 0.670221589057052 Up 0.429500726456215 CG12907 CG12907, isoform B - - - - 33499 1294.43 2.855 1.59 -0.844463980078488 Down 0.373431514991415 Ts Ts, isoform B K00560|1|0.0|666|dme:Dmel_CG3181|thymidylate synthase [EC:2.1.1.45] - GO:0042083//5,10-methylenetetrahydrofolate-dependent methyltransferase activity GO:0009177 318680 3431.00 1.005 1.165 0.213134453475352 Up 0.100250957601374 CG31320 CG31320 - - - - 32656 1243.40 30.21 20.35 -0.569997389574331 Down 0.605633337736098 CG34325 CG34325, isoform C K05760|1|8e-41|167|tca:658324|paxillin - GO:0046914//transition metal ion binding - 39887 1349.00 850.975 1019.645 0.260878296292402 Up 0.498514066833972 Rh4 rhodopsin 4 K13802|1|4e-55|216|dvi:Dvir_GJ10183|opsin Rh1 GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007602//phototransduction;GO:0009411//response to UV 38775 566.00 0.075 0.255 1.76553474636298 Up 0.153711530841368 Cpr65Ec cuticular protein 65Ec - - GO:0005198//structural molecule activity - 35410 1006.00 0.045 0.055 0.289506617194985 Up 0.0467903843613789 CG17570 CG17570 - - - - 43243 1950.18 11.64 10.435 -0.157660457748449 Down 0.245178972394664 CG14253 CG14253, isoform F - - - - 39167 1331.00 4.21 2.77 -0.603934257017208 Down 0.372143706247523 CG14164 CG14164, isoform B - - - - 34897 594.92 261.69 106.03 -1.30338627857608 Down 0.757396645093118 UK114 UK114, isoform B - - - GO:0044267//cellular protein metabolic process 8674064 368.00 2.09 6.015 1.52506179509519 Up 0.597741381587637 Sfp35C seminal fluid protein 35C - - - - 44900 2049.00 4.43 3.995 -0.149111195627041 Down 0.152588825782591 Larp7 La related protein 7 K11090|1|5e-17|89.7|nve:NEMVE_v1g236578|lupus La protein GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0003676//nucleic acid binding GO:0044260;GO:0019538//protein metabolic process;GO:0010467//gene expression 42109 1017.00 74.855 72.9 -0.0381798709269924 Down 0.131422533350944 Prx3 peroxiredoxin 3 K03386|1|1e-132|472|dme:Dmel_CG5826|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] - - - 39340 2762.68 1.045 1.04 -0.00691941393979047 Down 0.0382380134724607 CycA cyclin A, isoform C K06627|1|0.0|976|dme:Dmel_CG5940|cyclin A GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0043232;GO:0044444//cytoplasmic part GO:0019887//protein kinase regulator activity GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0045165//cell fate commitment;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition 44339 1325.72 30.545 13.845 -1.14157118671331 Down 0.700237749306565 imd immune deficiency, isoform B K02861|1|2e-07|57.4|ptr:462397|receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1] GO:0044464//cell part GO:0005488//binding GO:0048731;GO:0023060;GO:0023033;GO:0002780;GO:0031349//positive regulation of defense response 42525 751.00 123.515 131.63 0.0918020761526658 Up 0.236857746664906 AP-2sigma adaptor protein complex 2, sigma subunit K11827|1|2e-78|291|dvi:Dvir_GJ14442|AP-2 complex subunit sigma-1 GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030128//clathrin coat of endocytic vesicle GO:0005515//protein binding;GO:0022892 GO:0009653//anatomical structure morphogenesis;GO:0006901//vesicle coating;GO:0002164//larval development;GO:0015031//protein transport;GO:0009790//embryo development;GO:0050688//regulation of defense response to virus;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels 7354429 3245.00 1.025 1.125 0.134301091711591 Up 0.0767401928411042 CG42303 snurportin K13151|1|0.0|872|dsi:Dsim_GD13702|snurportin-1 - - - 32788 1625.41 24.74 28.82 0.220224835198378 Up 0.384658565579184 CG7206 CG7206, isoform C - - - - 48421 4182.99 22.31 23.68 0.085978567384809 Up 0.194954431382908 CG3558 CG3558, isoform D - - - - 19836061 1925.00 18.5 15.94 -0.214873641413203 Down 0.342953374719324 - CG45078 - - - - 33748 1673.00 1.275 1.13 -0.17417447444367 Down 0.0943402456742835 Cyp28d2 Cyp28d2 K00517|1|0.0|942|dme:Dmel_CG6081| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 32019 1844.34 112.85 82.47 -0.452465105845089 Down 0.613096024303262 CG1637 CG1637, isoform E - - GO:0043169//cation binding;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0016791//phosphatase activity - 36942 1904.00 0.32 0.555 0.794415866350106 Up 0.156815480121516 CG10950 CG10950 - - - - 34328 2780.67 15.815 15.42 -0.0364907906023593 Down 0.101175538238013 Dref DNA replication-related element factor, isoform B - GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0006355//regulation of transcription, DNA-dependent 41172 2197.00 4.32 3.035 -0.509334795907787 Down 0.344736494518558 CG8358 CG8358 K01389|1|0.0|1430|dme:Dmel_CG8358|neprilysin [EC:3.4.24.11];K08635|2|3e-59|230|nvi:100118995|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38404 2477.00 0.825 0.565 -0.546143251830628 Down 0.153282261260071 CG12017 CG12017, isoform D - - - - 41108 592.00 0.14 0.08 -0.807354922057604 Down 0.0821225729758288 HP1e heterochromatin protein 1e K11585|1|2e-100|363|dme:Dmel_CG8120|chromobox protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0005488//binding GO:0006325//chromatin organization 3771946 2245.00 2.145 2.045 -0.0688768045577966 Down 0.0677255316338661 CG13175 CG13175 K10903|1|4e-08|60.5|bfo:BRAFLDRAFT_84669|HUS1 checkpoint protein - - - 35213 2543.71 19.875 27.06 0.445206978917457 Up 0.552403909655264 CG17544 CG17544, isoform D K00232|1|0.0|1389|dme:Dmel_CG17544|acyl-CoA oxidase [EC:1.3.3.6] GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody GO:0030554//adenyl nucleotide binding;GO:0016634;GO:0030554//adenyl nucleotide binding;GO:0016634;GO:0030554//adenyl nucleotide binding;GO:0016634;GO:0030554//adenyl nucleotide binding;GO:0016634 GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process 35031 3249.00 22.34 27.1 0.278663665757919 Up 0.440067362303527 beat-IIIb beat-IIIb, isoform D - - - - 35592 396.00 19.665 17.06 -0.20501253962462 Down 0.344472328622375 ubl ubiquitin like K13113|1|6e-38|155|dsi:Dsim_GD10297|ubiquitin-like protein 5 GO:0044424//intracellular part - - 33495 2121.21 63.135 49.15 -0.361248593834268 Down 0.549762250693435 NTPase NTPase, isoform F K01511|1|4e-136|485|cqu:CpipJ_CPIJ005468|ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0017110//nucleoside-diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity - 36337 6585.69 15.465 17.76 0.199624748260841 Up 0.327301545370493 garz gartenzwerg, isoform C K12495|1|1e-29|133|dvi:Dvir_GJ11748|IQ motif and SEC7 domain-containing protein GO:0044464//cell part;GO:0044464//cell part GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity GO:0006909//phagocytosis;GO:0048193//Golgi vesicle transport;GO:0032011//ARF protein signal transduction;GO:0006909//phagocytosis;GO:0048193//Golgi vesicle transport;GO:0032011//ARF protein signal transduction 10178913 817.00 1.58 1.66 0.0712586831698219 Up 0.0633007528728041 CG42847 CG42847 - - - - 318582 615.00 1.45 0.86 -0.753644335312837 Down 0.253335094439308 CG31076 CG31076 K11092|1|6e-07|53.5|phu:Phum_PHUM308180|U2 small nuclear ribonucleoprotein A' - GO:0004091//carboxylesterase activity;GO:0005488//binding GO:0044238//primary metabolic process 43504 1241.45 42.99 33.195 -0.373035158461134 Down 0.540219257693832 CG1969 CG1969, isoform H K00621|1|3e-120|431|dya:Dyak_GE23878|glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4] - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 38788 8967.24 21.635 30.92 0.515173198502956 Up 0.58978338396513 Dscam2 down syndrome cell adhesion molecule 2, isoform R K06767|1|0.0|829|xtr:100216449|Down syndrome cell adhesion molecule;K06768|2|0.0|828|mmu:114873|Down syndrome cell adhesion molecule like 1 - - - 41416 3387.40 15.14 21.37 0.497221702674079 Up 0.553724739136177 CG12594 CG12594, isoform B K06236|1|2e-06|55.5|rno:60379|collagen, type I/II/III/V/XI, alpha - - GO:0042723//thiamine-containing compound metabolic process 40373 1787.46 65.77 74.805 0.185705033451844 Up 0.391658961828028 Syx6 syntaxin 6, isoform E K08498|1|2e-155|549|der:Dere_GG20169|syntaxin 6 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis 318603 1228.00 0.285 0.12 -1.24792751344359 Down 0.142385418042531 CG31131 CG31131 - - - - 53437 4748.89 38.405 28.32 -0.439472884213488 Down 0.571093646810197 Sulf1 sulfated, isoform C K01138|1|0.0|1894|dme:Dmel_CG6725| [EC:3.1.6.-] GO:0044431//Golgi apparatus part GO:0008484//sulfuric ester hydrolase activity GO:0007275//multicellular organismal development 40250 1523.00 19.61 18.535 -0.0813374203729932 Down 0.173623035266147 CG5498 CG5498 K12195|1|2e-08|60.8|api:100168253|charged multivesicular body protein 6 - - GO:0006810//transport 246551 1091.05 22.805 25.55 0.163973120967229 Up 0.308215559371285 CG30343 CG30343, isoform B - - - - 34883 1427.48 23.665 27.3 0.206146029068851 Up 0.36989829612997 TfIIS RNA polymerase II elongation factor, isoform B K03145|1|5e-119|428|dme:Dmel_CG3710|transcription elongation factor S-II GO:0043231//intracellular membrane-bounded organelle GO:0008135//translation factor activity, nucleic acid binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006354//DNA-dependent transcription, elongation;GO:0006355//regulation of transcription, DNA-dependent 3772111 678.00 0.535 0.695 0.377474086322361 Up 0.115308413683793 CG33792 CG33792 - - - - 43135 1408.00 1.8 0.845 -1.09097366004749 Down 0.341137234183067 CG31089 CG31089 K01046|1|9e-85|313|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3] - - GO:0044238//primary metabolic process 40920 1864.00 0.225 0.225 3.20342650381492e-16 Up 0.0382380134724607 CG10086 CG10086 - - - GO:0050877//neurological system process;GO:0023060 31536 1004.58 21.115 21.07 -0.00307793298399596 Down 0.0441487253995509 CG5941 CG5941, isoform B K07575|1|1e-101|370|dme:Dmel_CG5941|PUA domain protein - - - 31811 3247.19 2.34 2.875 0.297053426248333 Up 0.203110553427552 l(1)G0020 lethal (1) G0020, isoform B K06957|1|0.0|879|mcc:717452| - GO:0016407//acetyltransferase activity - 50001 1542.00 1.87 1.065 -0.812184839661799 Down 0.300521727644961 CG15864 CG15864 K00472|1|0.0|866|dme:Dmel_CG18749|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0019471 39034 4858.74 11.27 12.14 0.107280906083461 Up 0.186038832386739 smg smaug, isoform E - GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 49821 589.25 3366.98 2863.18 -0.233836780192241 Down 0.467705719191652 PebIII ejaculatory bulb protein III, isoform C K11321|1|7e-14|76.6|tca:661106|bromodomain-containing protein 8;K04352|2|6e-09|60.5|dan:Dana_GF20186|Ras GTPase-activating protein 1 - GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0051707//response to other organism 42861 1786.00 11.225 11.25 0.00320955647589006 Up 0.0427618544445912 CG5463 CG5463 K02434|1|3e-119|429|mmu:229487|aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] - GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0010467//gene expression 40562 4471.32 2.625 2.5 -0.070389327891398 Down 0.0725795799762251 Spargel spargel, isoform E K07202|1|3e-17|91.7|gga:422815|peroxisome proliferative activated receptor, gamma, coactivator 1, alpha - GO:0005488//binding;GO:0005488//binding - 38995 2155.12 18.08 17.21 -0.0711475803749839 Down 0.153711530841368 h hairy, isoform B K09090|1|4e-110|399|dsi:Dsim_GD14118|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016564//transcription repressor activity;GO:0003676//nucleic acid binding;GO:0016564//transcription repressor activity GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007423//sensory organ development;GO:0032989;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007365//periodic partitioning;GO:0001709//cell fate determination;GO:0006950//response to stress;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0035287//head segmentation;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007423//sensory organ development;GO:0032989;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007365//periodic partitioning;GO:0001709//cell fate determination;GO:0006950//response to stress;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0035287//head segmentation;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway 31544 2458.00 9.355 11.17 0.255819627242531 Up 0.333905692775063 Mipp2 multiple inositol polyphosphate phosphatase 2 K03103|1|0.0|862|dme:Dmel_CG4317|multiple inositol-polyphosphate phosphatase [EC:3.1.3.62];K07204|2|5e-121|435|dya:Dyak_GE16484|regulatory associated protein of mTOR - - - 31656 1973.00 40.405 42.95 0.0881242980682814 Up 0.217705719191652 CG4615 CG4615 K11064|1|0.0|663|dme:Dmel_CG4615|monocyte to macrophage differentiation protein - - - 318838 1268.00 0.76 0.51 -0.57550217147209 Down 0.15153216219786 CG33061 CG33061, isoform C - GO:0044464//cell part GO:0005216//ion channel activity GO:0006812//cation transport 31698 2763.70 10.59 10.03 -0.0783809833801556 Down 0.14109760929864 p115 p115, isoform B - - - - 31140 842.00 17.56 16.45 -0.0942052609127547 Down 0.184949148064985 MED18 mediator complex subunit 18, isoform C - - - - 41616 8905.00 17.695 22.275 0.332083669984054 Up 0.467375511821424 2mit 2mit, isoform D K06850|1|2e-17|92.8|gga:374173|slit 3;K13023|3|3e-17|91.7|ecb:100069043|carboxypeptidase N regulatory subunit - - - 40729 958.00 0.61 0.635 0.0579473492092795 Up 0.0489697530048871 CG14676 CG14676 - - - - 2768997 1456.00 23.745 28.195 0.247815586755034 Up 0.412561088363492 CG12038 CG12038 - - - - 38092 625.00 2.37 2.76 0.21978120787991 Up 0.158037247391362 CG13898 CG13898 K02183|1|2e-27|121|mdo:100015768|calmodulin GO:0042995//cell projection GO:0046872//metal ion binding - 50068 2279.33 11.485 9.63 -0.254143153534464 Down 0.330570598335755 CG33111 CG33111, isoform E K14000|1|2e-08|61.2|bfo:BRAFLDRAFT_66351|ribosome-binding protein 1;K11498|2|7e-08|59.7|nvi:100121143|centromeric protein E;K04648|3|3e-07|57.4|dre:100003026|dynactin 1;K06267|4|6e-07|56.6|cin:493183|hyaluronan-mediated motility receptor;K10421|5|8e-07|56.2|tgu:100219895|CAP-Gly domain-containing linker protein 1 - GO:0046872//metal ion binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003824//catalytic activity;GO:0005515//protein binding - 40621 1319.00 0.415 0.915 1.14066040693712 Up 0.251452912429005 Prosbeta2R2 proteasome beta2 subunit-related 2 K02739|1|7e-167|586|dme:Dmel_CG12161|20S proteasome subunit beta 2 [EC:3.4.25.1] GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0006508//proteolysis 41486 1561.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 Cyp313a5 Cyp313a5 K00517|1|0.0|904|dme:Dmel_CG15807| [EC:1.14.-.-] - - - 37822 3195.56 30.35 17.175 -0.821386417437582 Down 0.65882974507991 Sox14 Sox box protein 14, isoform C K09268|1|7e-40|166|nvi:100123293|transcription factor SOX4/11/12 (SOX group C) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis 37524 2721.00 19.215 14.95 -0.362087491977335 Down 0.474078721437062 GM130 golgi matrix protein 130 kD ortholog K10421|1|4e-12|73.9|tgu:100219895|CAP-Gly domain-containing linker protein 1;K12478|3|1e-11|72.4|bta:516259|early endosome antigen 1 - - - 39902 5532.57 10.8 11.23 0.0563266153497702 Up 0.11689340906089 CG3764 CG3764, isoform C - - GO:0005198//structural molecule activity - 5740610 318.00 0.425 0.16 -1.4093909361377 Down 0.181481970677586 CG34254 CG34254 - - GO:0016798//hydrolase activity, acting on glycosyl bonds GO:0044238//primary metabolic process 39337 1506.98 3.555 4.105 0.20753266215839 Up 0.185576542068419 CG11597 CG11597, isoform C K01090|1|9e-178|623|dme:Dmel_CG11597|protein phosphatase [EC:3.1.3.16] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0000278//mitotic cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0006464//cellular protein modification process;GO:0000278//mitotic cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0006464//cellular protein modification process;GO:0000278//mitotic cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0006464//cellular protein modification process 251270 1545.00 1.01 1.035 0.0352754747475305 Up 0.0480451723682473 CG33191 CG33191 - - - - 33957 3627.69 1.505 1.86 0.305539134348329 Up 0.166787742702417 sens-2 senseless-2, isoform B K09223|1|7e-76|286|spu:589099|growth factor independent 1 - GO:0005488//binding - 39458 2811.76 114.36 111.51 -0.0364094310481843 Down 0.13403117157575 CG10960 CG10960, isoform C K08145|1|8e-90|332|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 37113 769.71 17.205 14.395 -0.257260103173547 Down 0.381851802932241 GstE8 glutathione S transferase E8, isoform B K00799|1|6e-89|326|dme:Dmel_CG17531|glutathione S-transferase [EC:2.5.1.18] - - - 19834929 516.00 0.72 0.535 -0.428458015041166 Down 0.12696473385286 - CG45428 - - - - 41787 2654.00 0.54 0.94 0.799701349514169 Up 0.208790120195483 CG7362 CG7362 K00873|1|0.0|1745|dme:Dmel_CG7362|pyruvate kinase [EC:2.7.1.40] - - - 41713 2421.96 8.455 3.3 -1.35733873016417 Down 0.62465328226126 Pk1r pyrokinin 1 receptor, isoform E K05052|1|6e-53|208|dre:557276|neuromedin U receptor 1 - - - 19835964 821.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 41119 1179.00 1.01 0.5 -1.01435529297707 Down 0.250330207370228 Or85f odorant receptor 85f K08471|1|0.0|765|dme:Dmel_CG16755|gustatory receptor GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004930//G-protein coupled receptor activity GO:0007606//sensory perception of chemical stimulus 33256 1462.80 6.105 6.26 0.0361713619452149 Up 0.0723484348170651 Pex12 peroxin 12, isoform B K13345|1|8e-153|539|dme:Dmel_CG3639|peroxin-12 GO:0044439 GO:0046914//transition metal ion binding GO:0006996//organelle organization 33837 6762.76 19.765 23.14 0.227440909287876 Up 0.378912957337208 lid little imaginal discs, isoform F K11446|1|0.0|3024|dme:Dmel_CG9088|histone demethylase JARID1 [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032453//histone demethylase activity (H3-K4 specific);GO:0003676//nucleic acid binding;GO:0010484//H3 histone acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0032453//histone demethylase activity (H3-K4 specific);GO:0003676//nucleic acid binding;GO:0010484//H3 histone acetyltransferase activity;GO:0046914//transition metal ion binding GO:0070076//histone lysine demethylation;GO:0043966//histone H3 acetylation;GO:0070076//histone lysine demethylation;GO:0043966//histone H3 acetylation 43563 3119.63 48.04 47.35 -0.0208717253498871 Down 0.0860850614185709 Mgat2 Mgat2, isoform C K00736|1|0.0|1068|der:Dere_GG11975|alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0009311//oligosaccharide metabolic process;GO:0006487//protein N-linked glycosylation;GO:0009311//oligosaccharide metabolic process;GO:0006487//protein N-linked glycosylation 37699 703.48 89.52 79.275 -0.175344063985192 Down 0.382512217672698 CG34424 CG34424, isoform B K01934|1|5e-95|347|dpo:Dpse_GA10745|5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] GO:0043231//intracellular membrane-bounded organelle GO:0016882//cyclo-ligase activity;GO:0030234//enzyme regulator activity;GO:0032559 GO:0006760//folic acid-containing compound metabolic process;GO:0006140 41993 1025.67 29.915 26.935 -0.15138699781586 Down 0.303196407343812 CG14894 CG14894, isoform B K09527|1|9e-15|80.9|dre:406579|DnaJ homolog subfamily C member 7;K09553|5|4e-14|78.6|dpe:Dper_GL25924|stress-induced-phosphoprotein 1 - - - 19834827 334.00 0.66 1.85 1.48698734115786 Up 0.398098005547484 33709 2411.00 2.625 3.06 0.221214230139167 Up 0.167382115968828 Marcal1 Marcal1 K11727|1|7e-32|139|oaa:100078663|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:3.6.1.-];K10841|5|8e-31|135|ame:724695|DNA excision repair protein ERCC-6 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006325//chromatin organization 12798160 5108.80 0.035 0.055 0.652076696579693 Up 0.0550785893541144 42175 2060.00 6.24 5.2 -0.263034405833794 Down 0.265849953770968 MED17 mediator complex subunit 17 - - - - 45524 1680.00 102.405 35.59 -1.5247423197516 Down 0.760401532162198 Cyp4p1 cytochrome P450-4p1 K00517|1|0.0|968|dme:Dmel_CG10842| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 43528 5795.00 17.43 10.93 -0.67327916845378 Down 0.58839651301017 Cad99C cadherin 99C, isoform B K06813|1|1e-73|279|gga:423718|cadherin 23 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//cell-cell adhesion;GO:0016337//cell-cell adhesion 38718 3233.00 10.185 9.07 -0.167271524437366 Down 0.242801479329019 D19A D19A K09228|1|9e-41|169|ptr:469069|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 34367 2271.00 6.01 6.855 0.189791675068041 Up 0.22381455554088 Ror Ror K05122|1|0.0|1298|dme:Dmel_CG4926|receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1] GO:0016021//integral to membrane GO:0004713//protein tyrosine kinase activity;GO:0004888//transmembrane signaling receptor activity;GO:0032559 GO:0023060;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007399//nervous system development;GO:0006464//cellular protein modification process 31713 9365.57 14.585 15.685 0.104900142945425 Up 0.19369964337604 CG42593 CG42593, isoform C K11978|1|0.0|2226|dan:Dana_GF21293|E3 ubiquitin-protein ligase UBR3 [EC:6.3.2.19] - - - 42690 1531.00 4.2 3.805 -0.142492874162577 Down 0.145192180689473 CG4813 CG4813 - - GO:0046872//metal ion binding - 246534 1655.00 19.285 18.555 -0.0556711449312359 Down 0.138984282129177 CG30291 CG30291 - - - GO:0051726//regulation of cell cycle 35140 1360.81 20.84 12.43 -0.745528981226023 Down 0.62419099194294 CG17597 CG17597, isoform B K08764|1|0.0|820|dme:Dmel_CG17597|sterol carrier protein 2 [EC:2.3.1.176] GO:0042579//microbody GO:0005319//lipid transporter activity;GO:0016408;GO:0005496//steroid binding GO:0006869//lipid transport 34196 1133.00 36.54 40.7 0.155552160526121 Up 0.328952582221635 PrBP Prenyl-binding protein K13758|1|5e-82|304|dya:Dyak_GE10828|retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004112//cyclic-nucleotide phosphodiesterase activity GO:0050953//sensory perception of light stimulus;GO:0007420//brain development 14462383 470.00 0.185 0.105 -0.817135942850189 Down 0.0935147272487122 19835957 266.00 15.34 1.54 -3.31629622680803 Down 0.777473253203012 - CG43920, isoform C - - - - 31295 747.00 14.685 16.09 0.131821060398595 Up 0.236758684453837 CG3939 CG3939, isoform B K00771|1|8e-09|60.8|smm:Smp_128310.1|protein xylosyltransferase [EC:2.4.2.26] - - - 19835721 509.00 0.01 0.365 5.18982455888002 Up 0.305408796724343 43719 6479.00 1.06 1.25 0.237863830098888 Up 0.111114780081891 rod rough deal K11577|1|0.0|4006|dme:Dmel_CG1569|kinetochore-associated protein 1 - - - 38624 2689.26 43.89 9.505 -2.20713373821109 Down 0.774072117289658 CG10625 CG10625, isoform K - - GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity - 33013 1662.43 95.785 70.225 -0.447815027215439 Down 0.60913353586052 CG9572 CG9572, isoform D K02599|1|7e-26|118|aag:AaeL_AAEL010210|Notch - - - 43185 1184.00 0.425 0.8 0.912537158749661 Up 0.209417514198917 CG6036 CG6036 K01090|1|0.0|745|dme:Dmel_CG6036|protein phosphatase [EC:3.1.3.16];K04461|2|7e-103|374|mdo:100033369|protein phosphatase 1B (formerly 2C) [EC:3.1.3.16] GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 40836 1196.14 292.135 161.39 -0.856084024849237 Down 0.718399154669132 Sodh-1 sorbitol dehydrogenase 1, isoform B K00008|1|0.0|695|dme:Dmel_CG1982|L-iditol 2-dehydrogenase [EC:1.1.1.14] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046914//transition metal ion binding GO:0008152//metabolic process 38610 3237.16 34.27 38.385 0.163596456241428 Up 0.328391229692247 lama lamina ancestor, isoform D - - - - 7354381 1540.00 8.12 10.95 0.43137923730336 Up 0.447397965922599 tal-1A tal-1A - - - - 33677 1485.76 4.12 5.265 0.353789193842499 Up 0.303889842821292 CG3294 CG3294, isoform B K12836|1|1e-13|77.8|tgu:100190246|splicing factor U2AF 35 kDa subunit GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0000377;GO:0000377 33033 955.00 13.45 10.2 -0.399037020585129 Down 0.457568352925637 l(1)G0004 lethal (1) G0004 K11884|1|5e-114|410|dme:Dmel_CG11738|RNA-binding protein PNO1 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding - 32005 6499.62 14.62 17.875 0.289999930600677 Up 0.414014000792498 CG32676 CG32676, isoform B - - - - 8674054 322.00 1.225 1.72 0.489626815699528 Up 0.215427288337076 Sfp23F seminal fluid protein 23F - - - - 117464 553.00 0.345 0.33 -0.0641303374197154 Down 0.0422335226522256 He hemese, isoform C - - - GO:0002376//immune system process 7354398 2497.72 18.565 30.345 0.708873505424699 Up 0.638918240655131 CG42238 CG42238, isoform D - - - - 42689 2882.00 20.57 22.44 0.125530882083859 Up 0.255976753401136 Irp-1A iron regulatory protein 1A K01681|1|0.0|1734|dme:Dmel_CG4900|aconitate hydratase 1 [EC:4.2.1.3] - GO:0003729//mRNA binding;GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0016836//hydro-lyase activity GO:0006446//regulation of translational initiation 19835737 495.00 0.255 0.295 0.210217707390346 Up 0.0611874257033417 38436 3526.00 3.09 2.025 -0.609684930132387 Down 0.323735305772025 dar1 dendritic arbor reduction 1 K09206|1|2e-49|198|dre:562670|krueppel-like factor 5 GO:0044464//cell part GO:0046914//transition metal ion binding - 318866 500.48 7.65 8.335 0.123722451406403 Up 0.176859067494386 CG31639 CG31639, isoform B - - - - 41887 6339.93 9.38 5.86 -0.678687258093128 Down 0.51888786157707 CG14869 ADAM metallopeptidase with thrombospondin type 1 motif A, isoform E K09609|1|9e-168|592|bta:536137|a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-] - - - 33736 784.20 144.685 184.07 0.347339152900505 Up 0.567395324263638 His3.3A histone H3.3A, isoform D K11253|1|2e-55|214|nvi:100117018|histone H3 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0065008;GO:0007417//central nervous system development;GO:0007126//meiosis;GO:0009719;GO:0002164//larval development;GO:0033554//cellular response to stress;GO:0010259//multicellular organismal aging;GO:0040009//regulation of growth rate;GO:0009653//anatomical structure morphogenesis;GO:0034728//nucleosome organization;GO:0009790//embryo development;GO:0065008;GO:0007417//central nervous system development;GO:0007126//meiosis;GO:0009719;GO:0034728//nucleosome organization 43712 1435.00 0.52 0.725 0.479469371873842 Up 0.131785761458196 lox lysyl oxidase-like K00277|1|0.0|731|dme:Dmel_CG11335|protein-lysine 6-oxidase [EC:1.4.3.13];K00280|2|1e-64|247|dre:565508| [EC:1.4.3.-] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0004888//transmembrane signaling receptor activity GO:0043412//macromolecule modification;GO:0009987//cellular process 32215 1200.30 7.835 8.97 0.195174710446681 Up 0.257396645093118 Aven aven ortholog, isoform B - - - - 50246 423.13 624.51 619.89 -0.010712442483075 Down 0.0707964601769911 CoVIIc cytochrome c oxidase subunit VIIc, isoform D K02272|1|9e-33|138|dsi:Dsim_GD10709|cytochrome c oxidase subunit VIIc [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0005488//binding;GO:0015002//heme-copper terminal oxidase activity;GO:0005488//binding;GO:0015002//heme-copper terminal oxidase activity - 32597 2687.00 7.105 5.175 -0.457275786856093 Down 0.399352793554352 CalpC calpain C K08585|1|3e-94|346|nvi:100119123|calpain, invertebrate [EC:3.4.22.-];K08578|3|2e-92|340|tgu:100225062|calpain-9 [EC:3.4.22.-] GO:0044464//cell part GO:0046872//metal ion binding;GO:0004197//cysteine-type endopeptidase activity GO:0019538//protein metabolic process 40794 6313.00 8.77 9.42 0.10315021716805 Up 0.161669528463875 CG9727 CG9727, isoform C K08061|1|2e-26|122|dre:562498|regulatory factor X 5 - - - 40354 546.00 0.54 0.105 -2.36257007938471 Down 0.264165896182803 Edg78E Ecdysone-dependent gene 78E, isoform B - - GO:0005214//structural constituent of chitin-based cuticle - 38743 1031.00 2.02 2.17 0.103339749692685 Up 0.0833113195086514 eIF4E-4 eIF4E-4 K03259|1|8e-124|443|dme:Dmel_CG10124|translation initiation factor eIF-4E GO:0044424//intracellular part;GO:0043234//protein complex GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 41645 1535.00 1.19 1.235 0.053549468276734 Up 0.051182142385418 CG8870 CG8870 K01362|1|7e-45|181|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|9e-32|137|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - - - 41853 1449.61 538.785 388.78 -0.47075568179829 Down 0.636903975696738 Tm2 tropomyosin 2, isoform G K10373|1|3e-139|495|dpo:Dpse_GA18472|tropomyosin 1;K10374|2|1e-132|473|dme:Dmel_CG4843|tropomyosin 2 - - - 36688 594.00 25.405 24.555 -0.0490956416024032 Down 0.132248051776516 mRpL41 mitochondrial ribosomal protein L41 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 31065 2721.38 6.995 3.66 -0.934480408880711 Down 0.538898428212918 CG11380 CG11380, isoform B - - - - 43125 1894.00 7 8.2 0.228268987673117 Up 0.275029718663321 CG5886 CG5886 K11423|1|5e-13|76.3|dgr:Dgri_GH16034|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43];K10381|2|8e-12|72.4|mdo:100027776|desmoplakin;K10352|4|2e-11|71.2|gga:374069|myosin heavy chain - - - 318108 1233.00 0.42 0.11 -1.93288580414146 Down 0.210804385153877 CG32599 CG32599 - - - - 35381 1485.00 11.945 14.075 0.236728068511259 Up 0.342127856293752 E2f2 E2F transcription factor 2, isoform B K04682|1|7e-162|570|dya:Dyak_GE13001|E2F transcription factor 4/5 GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043234//protein complex GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0000278//mitotic cell cycle;GO:0006261//DNA-dependent DNA replication;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048513//organ development;GO:0007309//oocyte axis specification;GO:0022402//cell cycle process 33861 4462.42 18.705 22.915 0.292868319823486 Up 0.437524765552767 Kr-h1 kruppel homolog 1, isoform B K09228|1|5e-59|230|api:100159445|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0009653//anatomical structure morphogenesis;GO:0002165//instar larval or pupal development;GO:0010468//regulation of gene expression;GO:0009653//anatomical structure morphogenesis;GO:0002165//instar larval or pupal development 8674039 841.46 39.72 41.81 0.0739824205157638 Up 0.182142385418043 CG42518 CG42518, isoform B - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0016251//general RNA polymerase II transcription factor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent 318593 1142.18 3.66 4.285 0.227451555828457 Up 0.201591599524501 CG31105 pickpocket 22, isoform C K04832|1|3e-11|70.5|mmu:58170|amiloride-sensitive cation channel 5, intestinal;K04827|5|2e-08|60.8|bta:617802|nonvoltage-gated sodium channel 1 gamma GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 33689 1882.00 13.62 17.23 0.339195998212877 Up 0.449742438251222 CG11926 Mon1 ortholog - - - - 33910 3155.70 28.48 29.245 0.0382408427742595 Up 0.118016114119667 CG31638 CG31638, isoform B K10352|1|6e-23|110|dre:555454|myosin heavy chain - - - 246596 1657.58 47.305 51.63 0.126216917833346 Up 0.293125082551843 Tango11 transport and golgi organization 11, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - 35494 3558.70 56.17 22.8 -1.30076597852651 Down 0.735933166028266 laccase2 laccase 2, isoform G K00540|1|1e-25|119|cel:F21D5.3| [EC:1.-.-.-] - GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 3771893 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33909 histone H4 K11254|1|4e-40|163|dan:Dana_GF20391|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 35047 3287.44 23.75 21.075 -0.172394882276228 Down 0.316734909523181 dl dorsal, isoform F K09255|1|0.0|1006|dme:Dmel_CG6667|Rel/ankyrin family, other GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0070161;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045202//synapse GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019955//cytokine binding;GO:0003677//DNA binding GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development;GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development;GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development;GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development;GO:0035110;GO:0001752//compound eye photoreceptor fate commitment;GO:0007309//oocyte axis specification;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0008595//anterior/posterior axis specification, embryo;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051301//cell division;GO:0046666//retinal cell programmed cell death;GO:0002682//regulation of immune system process;GO:0000904//cell morphogenesis involved in differentiation;GO:0048666//neuron development;GO:0060541//respiratory system development;GO:0001703//gastrulation with mouth forming first;GO:0009996//negative regulation of cell fate specification;GO:0007297//ovarian follicle cell migration;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007293//germarium-derived egg chamber formation;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0042675//compound eye cone cell differentiation;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis;GO:0042386//hemocyte differentiation;GO:0010721//negative regulation of cell development 42141 2019.00 4.43 6.16 0.475623652139883 Up 0.385054814423458 CG17803 CG17803 K09228|1|4e-35|149|cfa:483055|KRAB domain-containing zinc finger protein - - - 42697 1099.00 7.525 7.24 -0.055701884563859 Down 0.100184916127328 CG17141 CG17141 K00308|1|2e-67|255|gga:395580|N1-acetylpolyamine oxidase [EC:1.5.3.13] GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding - 32448 7765.98 16.83 19.835 0.237013220815331 Up 0.375676925108968 CG43737 CG43737, isoform C - - - - 33110 4827.00 8.9 9.005 0.0169209400525156 Up 0.0586448289525822 fliI flightless I K05768|1|7e-61|236|hsa:85477|gelsolin - GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0001703//gastrulation with mouth forming first;GO:0010927 40204 1398.00 5.975 3.95 -0.597086059803645 Down 0.426132611279884 CG7328 CG7328 K00846|1|0.0|633|dme:Dmel_CG7328|ketohexokinase [EC:2.7.1.3] - - - 34953 1376.24 29.685 28.11 -0.0786506593883254 Down 0.187854972922996 EndoGI endonuclease G inhibitor, isoform C K10885|1|2e-07|57.0|dsi:Dsim_GD21940|ATP-dependent DNA helicase 2 subunit 2 GO:0043231//intracellular membrane-bounded organelle GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0004857//enzyme inhibitor activity GO:0060699//regulation of endoribonuclease activity;GO:0000726 47173 2395.72 289.35 317.94 0.13593888910687 Up 0.337967243428873 Men malic enzyme, isoform C K00029|1|0.0|1316|dme:Dmel_CG10120|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] - GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0043169//cation binding GO:0043648//dicarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process 246624 614.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG30458 CG30458 - - - - 31765 948.00 2.565 3.835 0.580267751895879 Up 0.350746268656716 CG15343 CG15343 K00275|1|3e-06|52.4|nve:NEMVE_v1g231487|pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] - GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0000166//nucleotide binding GO:0008614//pyridoxine metabolic process 3771817 313.00 8.595 9.435 0.134524878122385 Up 0.197662131818782 43498 1471.00 21.135 6.96 -1.60247490118206 Down 0.718498216880201 CG15506 CG15506 - - - - 34170 2816.99 87.84 65.82 -0.416352027880849 Down 0.592425042926958 Akap200 A kinase anchor protein 200, isoform G - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - GO:0046578//regulation of Ras protein signal transduction;GO:0048102//autophagic cell death;GO:0046578//regulation of Ras protein signal transduction;GO:0048102//autophagic cell death;GO:0046578//regulation of Ras protein signal transduction;GO:0048102//autophagic cell death;GO:0046578//regulation of Ras protein signal transduction;GO:0048102//autophagic cell death 43775 1185.92 88.905 95.365 0.101195320254805 Up 0.252278430854577 Crk Crk, isoform H K04438|1|1e-144|512|dme:Dmel_CG1587|proto-oncogene C-crk - - - 35052 1285.02 51.26 51.57 0.0086985669076397 Up 0.0641923127724211 Sgt small glutamine-rich tetratricopeptide containing protein, isoform B K09553|1|3e-21|102|bmy:Bm1_55560|stress-induced-phosphoprotein 1 - - GO:0007268//synaptic transmission 37783 774.00 23.98 24.87 0.0525748488026829 Up 0.133271694624224 CG5569 CG5569 K09008|1|3e-109|394|dme:Dmel_CG5569|hypothetical protein - - - 12798260 353.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 42237 6762.41 22.39 21.345 -0.068956365604959 Down 0.161933694360058 CG31224 CG31224, isoform C K09228|1|1e-60|236|cfa:484247|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 39896 623.00 4.295 2.785 -0.624980803798432 Down 0.381554616299036 CG13022 CG13022 - - - - 14462591 444.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 CG43829 CG43829 - - - - 45655 9772.94 16.72 16.905 0.0158751688124947 Up 0.0688152159556201 dom domino, isoform G K11320|1|0.0|2563|dpo:Dpse_GA24314|E1A-binding protein p400 [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0003702//RNA polymerase II transcription factor activity GO:0007447//imaginal disc pattern formation;GO:0051276//chromosome organization;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0002683//negative regulation of immune system process;GO:0008593//regulation of Notch signaling pathway;GO:0007292//female gamete generation;GO:0048534;GO:0009791//post-embryonic development;GO:0007447//imaginal disc pattern formation;GO:0051276//chromosome organization;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0002683//negative regulation of immune system process;GO:0008593//regulation of Notch signaling pathway;GO:0007292//female gamete generation;GO:0048534;GO:0009791//post-embryonic development;GO:0007447//imaginal disc pattern formation;GO:0051276//chromosome organization;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0002683//negative regulation of immune system process;GO:0008593//regulation of Notch signaling pathway;GO:0007292//female gamete generation;GO:0048534;GO:0009791//post-embryonic development 4379844 8500.00 9.55 11.275 0.239554795219632 Up 0.318220842689209 CG34113 CG34113, isoform P K00907|1|3e-16|88.6|cin:100176083|myosin-light-chain kinase [EC:2.7.11.18];K06467|4|1e-15|87.0|mmu:12483|CD22 antigen GO:0044464//cell part;GO:0044464//cell part - - 31136 3574.37 7.125 4.785 -0.574371089453441 Down 0.445680887597411 CG42666 CG42666, isoform K K01175|1|2e-48|194|hsa:254958| [EC:3.1.-.-];K12579|4|8e-15|83.2|oaa:100093227|interferon-stimulated gene 20 kDa protein [EC:3.1.13.1] GO:0044464//cell part;GO:0044464//cell part GO:0004518//nuclease activity;GO:0005488//binding;GO:0004518//nuclease activity;GO:0005488//binding - 3772116 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 3354884 610.00 0.135 0.225 0.736965594166206 Up 0.0970149253731343 CG40245 CG40245 - - GO:0046872//metal ion binding - 38859 2674.00 26.42 26.905 0.0262438402079463 Up 0.0960903447364945 CG7492 CG7492 - - - - 14462705 561.00 0.365 0.245 -0.575114714764809 Down 0.106161669528464 40547 1327.50 14.345 11.165 -0.361564716946191 Down 0.443567560427949 CG1103 CG1103, isoform B - - - - 33962 5209.25 22.8 26.56 0.220221322294821 Up 0.379573372077665 neuroligin neuroligin 2, isoform C K01044|1|0.0|2036|dme:Dmel_CG13772|carboxylesterase [EC:3.1.1.1];K07378|3|0.0|722|aga:AgaP_AGAP002090|neuroligin - GO:0005515//protein binding - 43292 3558.00 9.695 9.175 -0.0795327403762173 Down 0.137135120855897 CG3368 CG3368 - - - - 3346141 2570.11 71.64 59.48 -0.268360689933542 Down 0.478536520935147 CG33521 CG33521, isoform G K00920|1|5e-14|80.1|dya:Dyak_GE14484|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149];K00889|4|5e-14|80.1|dme:Dmel_CG17471|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] - - - 42425 1234.00 0.035 0.04 0.192645077942396 Up 0.0382380134724607 Or92a odorant receptor 92a K08471|1|0.0|801|dme:Dmel_CG17916|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 31384 3185.79 14.19 17.025 0.262780208838882 Up 0.382611279883767 Usf Usf, isoform C K09106|1|3e-11|71.2|rno:81817|upstream stimulatory factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity - 34338 2577.00 7.34 12.52 0.770382594089405 Up 0.580405494650641 Pen pendulin - GO:0015630//microtubule cytoskeleton;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0008565//protein transporter activity;GO:0003676//nucleic acid binding GO:0009629//response to gravity;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0006606//protein import into nucleus;GO:0007293//germarium-derived egg chamber formation 42849 1930.07 59.025 102.725 0.799389288939014 Up 0.698355567296262 CG5991 CG5991, isoform C K01613|1|0.0|887|dme:Dmel_CG5991|phosphatidylserine decarboxylase [EC:4.1.1.65] - GO:0016831//carboxy-lyase activity;GO:0016831//carboxy-lyase activity;GO:0016831//carboxy-lyase activity GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process 34846 813.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 Cpr35B cuticular protein 35B - - GO:0005198//structural molecule activity - 7354377 1540.00 8.12 10.95 0.43137923730336 Up 0.447397965922599 tal-AA tal-AA - - - - 41025 2837.00 28.53 30.095 0.0770440698196089 Up 0.187392682604676 p pink - GO:0044424//intracellular part GO:0005488//binding GO:0006623//protein targeting to vacuole;GO:0050953//sensory perception of light stimulus;GO:0042441//eye pigment metabolic process 31917 1413.00 61.64 52.555 -0.230038835399703 Down 0.432967903843614 Ser7 Ser7 K01312|1|9e-137|486|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4];K01362|2|2e-64|246|dme:Dmel_CG4920| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43413 2323.00 32.985 22.965 -0.52237332135518 Down 0.594637432307489 CG14526 CG14526 K01415|1|0.0|1166|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|3|2e-78|293|nvi:100118995|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 44118 1464.00 28.725 28.775 0.00250903548611707 Up 0.0441487253995509 vih vihar K06688|1|4e-96|352|dme:Dmel_CG10682|ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity;GO:0032559 GO:0060255;GO:0007049//cell cycle;GO:0032446//protein modification by small protein conjugation 33611 4142.03 19.445 25.97 0.417446779244199 Up 0.533780213974376 capu cappuccino, isoform J K02184|1|0.0|931|dme:Dmel_CG3399|formin 2 GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0007015//actin filament organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation 318701 1335.00 2.58 2.04 -0.338801913451759 Down 0.209582617884031 CG31380 CG31380 - - - - 36223 818.00 0.34 0.695 1.03147823147317 Up 0.205851274600449 iotaTry iotaTrypsin K01312|1|2e-133|474|dme:Dmel_CG7754|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36397 5786.00 2.465 2.415 -0.0295644575421382 Down 0.0530643243957205 CG8771 CG8771, isoform C - - - - 32940 1887.29 273.94 281.59 0.0397361610282863 Up 0.137663452648263 l(1)G0156 lethal (1) G0156, isoform D K00030|1|0.0|748|dsi:Dsim_GD15579|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0009060//aerobic respiration;GO:0009060//aerobic respiration 42943 1301.00 18.575 17.755 -0.0651368504049873 Down 0.15153216219786 CG13630 CG13630 K01265|1|0.0|793|dme:Dmel_CG13630|methionyl aminopeptidase [EC:3.4.11.18] - GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 326172 2267.00 0.865 1.165 0.429557917017556 Up 0.160744947827236 CG31918 CG31918 - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 318867 2938.00 3.14 2.925 -0.10232793442086 Down 0.0966847180029058 CG31643 CG31643, isoform B K08290|1|1e-09|65.9|mmu:66587|Fas-activated serine/threonine kinase [EC:2.7.11.8] - GO:0016301//kinase activity;GO:0032559 GO:0012501//programmed cell death 37220 3245.00 2.135 3.55 0.733582954771554 Up 0.383238673887201 CG9975 CG9975, isoform B - - - - 39099 4409.83 33.79 32.94 -0.0367557954374467 Down 0.11966715097081 CG32043 CG44838, isoform I - - - - 19836052 919.00 0.13 0.21 0.691877704637668 Up 0.0911042134460441 36324 1648.50 11.94 6.84 -0.803734606378907 Down 0.581131950865143 CG8854 CG8854, isoform C - - - - 46085 2258.82 20.315 19.2 -0.0814390536225693 Down 0.175108968432175 l(2)08717 lethal (2) 08717, isoform C K08193|1|1e-80|301|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|4|3e-71|270|cfa:474969|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 GO:0016020//membrane;GO:0016020//membrane - GO:0006950//response to stress;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006810//transport;GO:0006950//response to stress;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006810//transport 46187 2065.00 17.98 14.405 -0.319823360354577 Down 0.440232465988641 sinu sinuous - GO:0043296//apical junction complex - GO:0035150//regulation of tube size;GO:0021782//glial cell development;GO:0007043//cell-cell junction assembly 42197 2040.00 2.94 4.67 0.667606394873298 Up 0.407574957073042 CG7131 CG7131 - - - - 39628 1034.00 119.105 80.38 -0.567325495963867 Down 0.655032360322282 Prosbeta2 proteasome beta2 subunit K02739|1|1e-146|519|dme:Dmel_CG3329|20S proteasome subunit beta 2 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0006508//proteolysis 19835826 410.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 3772543 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 35325 4892.00 11.17 12.025 0.106407708174089 Up 0.184949148064985 bru brunelleschi - - - - 42171 3405.37 32.74 34.72 0.0847126259703261 Up 0.195482763175274 cdm cadmus, isoform B - - - - 43679 889.00 0.18 0.35 0.959358015502654 Up 0.136144498745212 Prosalpha3T proteasome alpha3 subunit, Testis-specific K02728|1|4e-144|511|dme:Dmel_CG1736|20S proteasome subunit alpha 3 [EC:3.4.25.1] GO:0015630//microtubule cytoskeleton;GO:0043073//germ cell nucleus;GO:0005839//proteasome core complex GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0007052//mitotic spindle organization 19835649 361.00 0.365 1.02 1.48260078309148 Up 0.301809536388852 14462410 357.00 6.27 4.255 -0.559306311116076 Down 0.421377625148593 CG43841 CG43841 - - - - 38836 1467.53 0.525 0.69 0.394278939112046 Up 0.118544445912033 Tsp66A tetraspanin 66A, isoform F - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 33702 1318.00 1.595 1.575 -0.0182045953775903 Down 0.0440166424514595 CG14044 CG14044 - - - - 43782 4621.24 38.065 45.23 0.248814917767181 Up 0.440793818518029 NfI nuclear factor I, isoform C K09172|1|0.0|1436|dme:Dmel_CG2380|nuclear factor I, invertebrate - - - 31519 2279.54 25.265 26.115 0.0477385237543047 Up 0.132248051776516 CG3016 CG3016, isoform B K11851|1|0.0|1046|dme:Dmel_CG3016|ubiquitin carboxyl-terminal hydrolase 30 [EC:3.1.2.15] - - - 37138 2136.00 24.64 21.41 -0.202717460309392 Down 0.353850217936864 CG5327 CG5327 K00456|1|1e-131|470|dme:Dmel_CG5493|cysteine dioxygenase [EC:1.13.11.20] - - - 8673984 522.00 5.53 11.09 1.003907979927 Up 0.611742174085326 Sfp24Ba seminal fluid protein 24Ba - - - - 42246 3108.01 0.15 0.17 0.180572245641821 Up 0.0511161009113723 Muc91C mucin 91C, isoform B - - - - 33948 2425.86 13.735 12.635 -0.120431246131081 Down 0.210276053361511 CG11221 CG11221, isoform B K08858|1|0.0|818|dpo:Dpse_GA10851|SH3-binding domain kinase 1 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 40433 3013.07 10.125 9.76 -0.0529688550964632 Down 0.105270109628847 Nopp140 Nopp140, isoform F - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - 38184 3764.82 7 7.2 0.0406419844973461 Up 0.080768722757892 CG7879 CG7879, isoform B K12898|1|4e-08|61.2|ecb:100050002|heterogeneous nuclear ribonucleoprotein F/H GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 46194 8863.21 20.845 26.235 0.33179141783442 Up 0.482003698322547 Spn spinophilin, isoform T K06095|1|5e-13|78.6|rno:29365|multiple PDZ domain protein - - - 37897 1177.00 1.575 2.385 0.598637437618233 Up 0.283681151763307 CG42383 CG42383 K14012|1|3e-40|166|dya:Dyak_GE23981|UBX domain-containing protein 1 - - - 33391 1038.00 6.205 6.455 0.056985885176834 Up 0.0939439968300092 CG15382 CG15382 - - - - 34939 2607.39 16.75 21.49 0.359504387195287 Up 0.483753797384758 beat-Ib beaten path Ib, isoform B - - GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process;GO:0007414//axonal defasciculation;GO:0007411//axon guidance;GO:0019538//protein metabolic process;GO:0007414//axonal defasciculation;GO:0007411//axon guidance 43262 3301.00 3.08 3.275 0.0885645557299111 Up 0.0906419231277242 eater eater K06825|1|2e-63|244|bta:281154|fibrillin 1 - - - 40020 2912.00 4.255 4.935 0.213890952770435 Up 0.206313564918769 star1 allatostatin C receptor 1 K04218|1|7e-61|236|bfo:BRAFLDRAFT_90879|somatostatin receptor 2 GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 19834767 671.00 0.125 0.135 0.111031312388744 Up 0.0437194558182539 33137 5718.16 56.845 74.64 0.392915528759718 Up 0.572315414080042 l(1)G0196 lethal (1) G0196, isoform P K13024|1|0.0|2148|dya:Dyak_GE17941|inositol hexakisphosphate/diphosphoinositol-pentakisphosphate kinase [EC:2.7.4.21 2.7.4.24] - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity - 43086 1758.00 0.05 0.035 -0.514573172829758 Down 0.0473847576277902 CG4582 CG4582 K01059|1|0.0|870|dme:Dmel_CG4582|lipoprotein lipase [EC:3.1.1.34];K01046|3|1e-36|154|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|3|1e-36|154|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 35674 1432.00 50.46 42.25 -0.256188864919391 Down 0.454893673226786 p47 p47 K14012|1|0.0|645|dme:Dmel_CG11139|UBX domain-containing protein 1 - - GO:0006998//nuclear envelope organization 31153 3459.00 6.985 6.945 -0.00828542142807031 Down 0.0472856954167217 mip130 Myb-interacting protein 130 - - - - 34982 4961.58 9.505 9.765 0.0389334172382398 Up 0.0883634922731475 dac dachshund, isoform G - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0046552//photoreceptor cell fate commitment;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0007560//imaginal disc morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0046552//photoreceptor cell fate commitment;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0007560//imaginal disc morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0046552//photoreceptor cell fate commitment;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0007560//imaginal disc morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0046552//photoreceptor cell fate commitment;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0007560//imaginal disc morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0046552//photoreceptor cell fate commitment;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0007560//imaginal disc morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0046552//photoreceptor cell fate commitment;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0007560//imaginal disc morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation 33163 1378.00 1.51 2.68 0.827684451132693 Up 0.359100515123498 CG11374 CG11374 K10091|1|2e-14|80.5|xtr:496937|galectin-4;K06832|2|2e-14|80.5|tgu:100227037|galectin-8;K10093|3|2e-14|80.5|hsa:284194|galectin-9 GO:0044444//cytoplasmic part GO:0048029//monosaccharide binding - 34162 767.00 2.05 2.515 0.294934490300081 Up 0.184916127327962 Acp29AB accessory gland protein 29AB K05328|1|4e-07|55.1|dan:Dana_GF15877|transient receptor potential cation channel subfamily C, invertebrate - GO:0048029//monosaccharide binding GO:0019098//reproductive behavior;GO:0046692//sperm competition 7354422 433.00 15.885 15.13 -0.0702531024967553 Down 0.148064984810461 CG42239 CG42239 - - - - 43176 1210.00 0.8 0.905 0.177917792195843 Up 0.0812640338132347 CG14556 CG14556 - - - - 7354373 1350.00 0.035 0.035 0 - 0.0382380134724607 CG42357 CG42357 - - - - 34069 2382.67 29.21 28.345 -0.0433680890097525 Down 0.12012944128913 CG7115 CG7115, isoform E K01090|1|2e-24|114|nve:NEMVE_v1g167304|protein phosphatase [EC:3.1.3.16];K04461|5|2e-21|104|spu:585672|protein phosphatase 1B (formerly 2C) [EC:3.1.3.16] GO:0043234//protein complex;GO:0043234//protein complex GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0065008;GO:0006464//cellular protein modification process;GO:0065008;GO:0006464//cellular protein modification process 31914 1543.29 32.025 33.43 0.0619447843883944 Up 0.159589222031436 CG1354 CG1354, isoform E K06942|1|4e-176|617|dya:Dyak_GE17809| GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding - 14462862 354.00 4.61 4.355 -0.0820940318304734 Down 0.0990952318055739 CG43680 CG43680 - - - - 41690 999.00 14.135 11.315 -0.321035298564283 Down 0.41520274732532 CG9286 CG9286 - - - - 42763 425.00 1.585 1.835 0.211297222703805 Up 0.123464535728437 CG42827 CG42827, isoform D K08117|1|1e-08|59.3|tgu:100222411|amyloid beta (A4) precursor-like protein 2;K03909|2|1e-08|59.3|ssc:100155068|tissue factor pathway inhibitor;K04520|4|3e-08|57.8|rno:54226|amyloid beta (A4) protein - GO:0004866//endopeptidase inhibitor activity - 43099 1397.00 1.2 1.73 0.527737632028206 Up 0.224144762911108 CG4730 CG4730, isoform C K09228|1|9e-29|128|ecb:100064925|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19835783 419.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 34145 1608.00 35.87 33.785 -0.0863948901756725 Down 0.211068551050059 CG14274 CG14274 - - - - 35070 13256.49 13.215 17.56 0.410116419893788 Up 0.491909919429402 CadN Cadherin-N, isoform L K10414|1|0.0|2243|dmo:Dmoj_GI22290|dynein heavy chain 2, cytosolic GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization;GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization 37954 5187.07 19.175 18.825 -0.0265767128310053 Down 0.0899154669132215 CG30421 CG30421, isoform C K11852|1|0.0|1930|dme:Dmel_CG30421|ubiquitin carboxyl-terminal hydrolase 31 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process 38385 5166.07 12.26 11.905 -0.0423913584204475 Down 0.0987650244353454 Girdin girdin, isoform E K08408|1|1e-57|226|cfa:480418|G protein-coupled receptor 68;K12478|3|2e-24|115|mcc:710381|early endosome antigen 1 - GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding GO:0006022;GO:0006022 42738 5213.37 15.78 17.06 0.112520441304832 Up 0.212587504953111 unk unkempt, isoform F - GO:0044424//intracellular part;GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0001654//eye development;GO:0009887//organ morphogenesis;GO:0009791//post-embryonic development;GO:0001654//eye development;GO:0009887//organ morphogenesis;GO:0009791//post-embryonic development 42651 588.00 3.215 6.45 1.00448042298267 Up 0.542002377493066 CG7046 CG7046, isoform B K09272|1|3e-12|70.9|mdo:100025230|structure-specific recognition protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 32665 1647.00 5.28 5.315 0.00953176217265119 Up 0.0472856954167217 Rrp45 Rrp45, isoform B K03678|1|0.0|796|dme:Dmel_CG9606|exosome complex component RRP45 GO:0000178//exosome (RNase complex) GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0010467//gene expression 3772138 310.51 49.995 53.075 0.0862486479613357 Up 0.222394663848897 IM18 immune induced molecule 18, isoform B - - - - 38142 4006.88 14.24 23.22 0.705418825899169 Up 0.622044644036455 CG32333 CG32333, isoform C - - - - 12798144 455.00 0.095 0.21 1.14438990933517 Up 0.118082155593713 CG43207 CG43207 - - - - 40193 743.51 39.98 34.52 -0.211846007565673 Down 0.393012812045965 CG14184 CG14184, isoform B - - - - 4379886 668.00 29.625 30.08 0.0219894130046535 Up 0.081858407079646 CG34125 CG34125 - - - - 39054 8484.87 38.41 50.98 0.408449409491137 Up 0.567791573107912 Rdl resistant to dieldrin, isoform G K05270|1|9e-93|341|cel:F11H8.2|gamma-aminobutyric acid (GABA) receptor, invertebrate;K05181|5|3e-73|276|mdo:100014538|gamma-aminobutyric acid (GABA) A receptor beta-1 GO:0044459//plasma membrane part;GO:0030672//synaptic vesicle membrane;GO:0034702//ion channel complex;GO:0044459//plasma membrane part;GO:0030672//synaptic vesicle membrane;GO:0034702//ion channel complex;GO:0044459//plasma membrane part;GO:0030672//synaptic vesicle membrane;GO:0034702//ion channel complex GO:0030594//neurotransmitter receptor activity;GO:0005253//anion channel activity;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0005253//anion channel activity;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0005253//anion channel activity;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity GO:0006810//transport;GO:0050804//regulation of synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0022410;GO:0017085//response to insecticide;GO:0009605//response to external stimulus;GO:0006810//transport;GO:0050804//regulation of synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0022410;GO:0017085//response to insecticide;GO:0009605//response to external stimulus;GO:0006810//transport;GO:0050804//regulation of synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0022410;GO:0017085//response to insecticide;GO:0009605//response to external stimulus 39135 5907.99 14.13 16.9 0.258261780835607 Up 0.380597014925373 CG16711 CG16711, isoform C - - - - 41321 1408.00 0.705 0.575 -0.294061301454418 Down 0.0994584599128253 Tengl4 testis EndoG-Like 4 K01173|1|7e-39|161|aag:AaeL_AAEL002064|endonuclease [EC:3.1.30.-] - GO:0003824//catalytic activity;GO:0043169//cation binding - 33427 5828.66 65.73 67.41 0.036410640189685 Up 0.129771496499802 VGlut vesicular glutamate transporter, isoform C K12302|1|0.0|1187|dme:Dmel_CG9887|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8 - - GO:0006810//transport 40032 4210.02 15.575 16.935 0.120775823582793 Up 0.224673094703474 MYPT-75D MYPT-75D, isoform C K06270|1|2e-48|194|tgu:100220857|protein phosphatase 1 regulatory subunit 12A;K12329|2|2e-48|194|cfa:490230|protein phosphatase 1 regulatory subunit 12B - - GO:0007472//wing disc morphogenesis 33135 2394.07 58.995 44.36 -0.411333321502357 Down 0.574659886408665 CG12576 CG12576, isoform F - - - - 36057 1525.00 31.73 27.12 -0.226490342781294 Down 0.400178311979923 Jra Jun-related antigen, isoform C K04449|1|8e-102|370|dpo:Dpse_GA15338|transcription factor jun-D;K04448|2|1e-45|184|cqu:CpipJ_CPIJ000084|transcription factor AP-1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0006909//phagocytosis;GO:0002759//regulation of antimicrobial humoral response;GO:0003006//developmental process involved in reproduction;GO:0001752//compound eye photoreceptor fate commitment;GO:0006355//regulation of transcription, DNA-dependent;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0007416//synapse assembly;GO:0000165//MAPK cascade;GO:0006909//phagocytosis;GO:0002759//regulation of antimicrobial humoral response;GO:0003006//developmental process involved in reproduction;GO:0001752//compound eye photoreceptor fate commitment;GO:0006355//regulation of transcription, DNA-dependent;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0007416//synapse assembly;GO:0000165//MAPK cascade 39749 1277.00 15.19 18.17 0.258436549732032 Up 0.387663452648263 mRpS31 mitochondrial ribosomal protein S31 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity - 19835678 3725.00 0.07 1.26 4.16992500144231 Up 0.474937260599657 - pre-mod(mdg4)-K - - - - 39478 1205.44 3.225 2.79 -0.209034038481429 Down 0.163617751948223 ste14 isoprenylcysteine carboxylmethyltransferase, isoform B K00587|1|2e-177|622|dme:Dmel_CG11268|protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100] GO:0031224//intrinsic to membrane GO:0003880//protein C-terminal carboxyl O-methyltransferase activity GO:0006479//protein methylation 42032 2289.00 44.795 24.405 -0.87616095649387 Down 0.686666226390173 modSP modular serine protease K06233|1|3e-30|134|cin:100183506|low density lipoprotein-related protein 2 - - - 36918 2956.46 53.135 62.515 0.23453991833448 Up 0.434486857746665 CG9646 CG9646, isoform B - - - - 3772344 1245.00 3.645 3.175 -0.199162222667409 Down 0.169990754193634 CG33785 CG33785 K03019|1|9e-163|386|dpo:Dpse_GA17233|DNA-directed RNA polymerase III subunit C11 [EC:2.7.7.6] GO:0044451//nucleoplasm part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity GO:0010468//regulation of gene expression 40216 1136.00 0.28 0.085 -1.71989208080727 Down 0.162329943204332 CG17147 CG17147 - - - - 19836021 347.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 12798114 929.00 4.435 4.845 0.127562561114017 Up 0.144069475630696 3355123 2590.00 39.39 20.895 -0.914671658291634 Down 0.685411438383305 CG40006 CG40006 K13885|1|2e-51|204|bta:282346|scavenger receptor class B, member 1 GO:0044464//cell part - GO:0009987//cellular process 35974 7332.82 21.68 28.13 0.375744795960828 Up 0.519019944525162 Camta Calmodulin-binding transcription activator, isoform I - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009586;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009586;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009586;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009586;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009586;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process 44039 4215.21 20.635 23.21 0.169653084337448 Up 0.31359793950601 Pak PAK-kinase, isoform J K04409|1|0.0|1023|dsi:Dsim_GD19869|p21-activated kinase 1 [EC:2.7.11.1] GO:0043232;GO:0043232;GO:0043232;GO:0043232 GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0065008;GO:0007265//Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0006935//chemotaxis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process;GO:0065008;GO:0007265//Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0006935//chemotaxis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process;GO:0065008;GO:0007265//Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0006935//chemotaxis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process;GO:0065008;GO:0007265//Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0006935//chemotaxis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006464//cellular protein modification process 34044 4524.10 43.575 37.505 -0.216417722226473 Down 0.40721172896579 Tep2 Thioester-containing protein 2, isoform G K06530|1|0.0|2657|dme:Dmel_CG7052|CD109 antigen GO:0044421//extracellular region part;GO:0044421//extracellular region part;GO:0044421//extracellular region part;GO:0044421//extracellular region part;GO:0044421//extracellular region part GO:0005488//binding;GO:0061135;GO:0005488//binding;GO:0061135;GO:0005488//binding;GO:0061135;GO:0005488//binding;GO:0061135;GO:0005488//binding;GO:0061135 GO:0042742//defense response to bacterium;GO:0006909//phagocytosis;GO:0042742//defense response to bacterium;GO:0006909//phagocytosis;GO:0042742//defense response to bacterium;GO:0006909//phagocytosis;GO:0042742//defense response to bacterium;GO:0006909//phagocytosis;GO:0042742//defense response to bacterium;GO:0006909//phagocytosis 40401 3401.88 26.285 33.535 0.35142786714289 Up 0.512679963016775 CG7166 CG7166, isoform C K06772|1|5e-24|114|hsa:4045|limbic system-associated membrane protein GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent 40709 3986.00 3.81 4.32 0.181240314670147 Up 0.172665433892484 Sym symplekin K06100|1|0.0|687|bfo:BRAFLDRAFT_202268|symplekin GO:0005849//mRNA cleavage factor complex - GO:0008334//histone mRNA metabolic process;GO:0006397//mRNA processing 36503 1412.00 0.84 0.765 -0.134929580086109 Down 0.0716219786025624 CG13331 CG13331 - - - - 42543 4722.00 4.325 4.73 0.129140050815309 Up 0.144069475630696 CG7922 CG7922, isoform B K10896|1|0.0|2719|dme:Dmel_CG7922|fanconi anemia group M protein [EC:3.6.1.-] - GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled - 36142 724.00 28.53 35.595 0.319194854333385 Up 0.495211993131687 RpS15Ab ribosomal protein S15Ab K02957|1|8e-71|266|dme:Dmel_CG12324|small subunit ribosomal protein S15Ae GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 38170 622.79 3.66 6.315 0.78693908550351 Up 0.492042002377493 robl62A robl62A, isoform B K10419|1|7e-06|50.8|phu:Phum_PHUM551150|dynein light chain roadblock-type GO:0005875//microtubule associated complex GO:0016887//ATPase activity GO:0007017//microtubule-based process 35942 1690.00 0.315 0.245 -0.362570079384708 Down 0.0818253863426232 unpg unplugged K09321|1|0.0|739|dme:Dmel_CG1650|homeobox protein GBX GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007417//central nervous system development;GO:2000026//regulation of multicellular organismal development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007424//open tracheal system development 2768834 561.00 0.085 0.1 0.234465253637023 Up 0.0521727644961036 CG33467 CG33467, isoform B - - GO:0016301//kinase activity GO:0006464//cellular protein modification process 3772328 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 40120 781.00 0.055 0.075 0.447458976971221 Up 0.0547483819838859 Cpr76Ba cuticular protein 76Ba - - GO:0042302//structural constituent of cuticle - 31903 1760.00 9.04 8.23 -0.135430341993562 Down 0.199544313829085 Lst8 Lst8 K08266|1|0.0|659|dme:Dmel_CG3004|G protein beta subunit-like GO:0044424//intracellular part GO:0017111//nucleoside-triphosphatase activity - 35648 5335.27 4.235 4.74 0.16252508956606 Up 0.166688680491349 Br140 Br140, isoform B K11348|1|0.0|674|mmu:78783|bromodomain and PHD finger-containing protein 1 GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 42512 1855.00 13.09 6.975 -0.908199975228691 Down 0.612204464403646 CG10824 CG10824 K05401|1|1e-16|88.6|dme:Dmel_CG5195|toll-like recepto 3 - GO:0005488//binding - 2768693 728.00 0.245 0.15 -0.70781924850669 Down 0.0998877294941223 CG33483 CG33483, isoform B K09255|1|2e-27|122|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|5e-12|71.2|dpo:Dpse_GA17766|WD repeat-containing protein 61 - GO:0016746//transferase activity, transferring acyl groups;GO:0016746//transferase activity, transferring acyl groups - 35198 1839.00 8.315 7.64 -0.12214362525152 Down 0.17434949148065 CG17568 CG17568 K09228|1|5e-35|149|ptr:455898|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 41963 2206.00 4.945 1.29 -1.93859945533586 Down 0.603486989829613 CG8925 CG8925, isoform B K08202|1|4e-49|196|der:Dere_GG11272|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - - 19836056 386.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 37310 4094.81 33.84 30.47 -0.151340068433464 Down 0.308776911900674 CG12484 CG12484, isoform E K06491|1|2e-20|102|dre:767777|neural cell adhesion molecule - - - 41625 7614.39 56 63.035 0.170726276131551 Up 0.35959582617884 Ace acetylcholine esterase, isoform C K01049|1|0.0|1284|dme:Dmel_CG17907|acetylcholinesterase [EC:3.1.1.7] GO:0044424//intracellular part;GO:0016020//membrane GO:0042802//identical protein binding;GO:0004091//carboxylesterase activity GO:0019695//choline metabolic process;GO:0006581//acetylcholine catabolic process;GO:0017085//response to insecticide 43354 2841.00 73.26 57.395 -0.352100639919001 Down 0.548705587108704 Gp93 glycoprotein 93 K09487|1|0.0|1311|dme:Dmel_CG5520|heat shock protein 90kDa beta GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0032559 GO:0050896//response to stimulus;GO:0048546//digestive tract morphogenesis;GO:0044267//cellular protein metabolic process 31574 6845.84 10.375 13.775 0.40894098233687 Up 0.465262184651961 CG15894 CG15894, isoform D K04456|1|1e-37|159|tca:656423|RAC serine/threonine-protein kinase [EC:2.7.11.1] - - - 36271 2038.95 1566.8 1420.37 -0.14155423914091 Down 0.343085457667415 Ef1alpha48D elongation factor 1alpha48D, isoform E K03231|1|0.0|900|der:Dere_GG20229|elongation factor EF-1 alpha subunit [EC:3.6.5.3] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006412//translation;GO:0006412//translation 32911 2123.00 0.555 0.605 0.124447370924489 Up 0.0607251353850218 CG14195 CG14195, isoform B - - - - 35971 2513.24 128.265 100.9 -0.346201377783303 Down 0.561583674547616 ced-6 ced-6, isoform F K06972|1|4e-61|236|tca:663047|;K12474|2|7e-14|79.7|dre:100000284|low density lipoprotein receptor adapter protein 1 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007420//brain development;GO:0007420//brain development;GO:0007420//brain development 35709 1782.00 15.59 16.705 0.0996590546371855 Up 0.194260995905429 CG12042 CG12042 K10426|1|0.0|976|dme:Dmel_CG12042|dynactin 4 GO:0005875//microtubule associated complex - - 31433 1088.00 0.145 0.52 1.84245872301352 Up 0.234876502443535 CG6789 regulatory particle non-ATPase 13-related - GO:0043231//intracellular membrane-bounded organelle - - 19835393 1093.00 2.9 3.39 0.225232373121409 Up 0.178708228767666 - CG44437 - - - - 36018 976.00 104.855 67.185 -0.642184585813537 Down 0.669000132082948 Prosalpha7 proteasome alpha7 subunit K02727|1|2e-141|501|dme:Dmel_CG1519|20S proteasome subunit alpha 7 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 43583 3522.90 2.86 3.06 0.0975165059142625 Up 0.094670453044512 AdoR adenosine receptor, isoform B K04266|1|3e-57|223|bfo:BRAFLDRAFT_139336|adenosine receptor A2a GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 48340 756.00 0.21 0.355 0.757429696725922 Up 0.118214238541804 GstD7 glutathione S transferase D7 K00799|1|9e-127|452|dme:Dmel_CG4371|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity - 40088 3861.00 6.475 9.085 0.4886063216602 Up 0.449280147932902 CG14082 CG14082, isoform E - - - - 36000 1187.00 0.535 0.595 0.153350776906797 Up 0.0670320961563862 CG10459 CG10459 K13137|1|1e-172|605|dsi:Dsim_GD10677|serine-threonine kinase receptor-associated protein - - - 19835058 1569.00 0.125 0.06 -1.05889368905357 Down 0.0856557918372738 41187 1281.00 16.65 13.735 -0.277665266882768 Down 0.397635715229164 CG12948 CG12948, isoform B - - - - 39918 1418.00 30.44 17.195 -0.823979242976755 Down 0.659093910976093 CG7724 CG7724 K00070|1|0.0|784|dme:Dmel_CG7724|3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1] - GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0008202//steroid metabolic process 40072 2419.00 1.88 1.185 -0.665845602779378 Down 0.265651829348831 CG11619 CG11619 - - GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity GO:0023033;GO:0019400 31562 592.35 80.4 59.44 -0.435761385527695 Down 0.600085853916259 CG3566 CG3566, isoform D K10595|1|3e-13|77.0|bfo:BRAFLDRAFT_73255|E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19];K10226|4|2e-09|64.3|smm:Smp_132740|fatty acid desaturase 2 (delta-6 desaturase) [EC:1.14.19.-] - - - 35183 1753.00 0.11 0.075 -0.552541023028779 Down 0.0683529256373002 CG10700 CG10700 K00530|1|0.0|1090|dme:Dmel_CG10700| [EC:1.18.1.-];K04727|2|1e-16|88.2|mcc:702773|programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] GO:0044424//intracellular part GO:0030554//adenyl nucleotide binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0019725//cellular homeostasis 39524 2782.37 15.57 13.875 -0.166281172954206 Down 0.281105534275525 Liprin-beta Liprin-beta, isoform C - - - - 41931 1645.00 15.29 14.09 -0.117916795051168 Down 0.216649055606921 CG3303 CG3303 K08014|1|2e-32|140|gga:426888|Rap guanine nucleotide exchange factor (GEF) 3;K01362|2|2e-30|134|mmu:19011| [EC:3.4.21.-] - - - 5740297 762.00 1.175 1.19 0.0183008167429437 Up 0.0413749834896315 CG34256 CG34256 - - - - 5740640 499.00 0.085 0.28 1.71989208080726 Up 0.162329943204332 CG34289 CG34289, isoform C K12031|1|1e-06|51.2|dre:100149099|tripartite motif-containing protein 65;K12015|2|4e-06|49.3|ecb:100051513|tripartite motif-containing protein 39 - GO:0046914//transition metal ion binding - 40790 1938.00 14.73 14.255 -0.0472893910978966 Down 0.114714040417382 TfIIFalpha transcription factor IIFalpha K03138|1|1e-115|417|dya:Dyak_GE10218|transcription initiation factor TFIIF alpha subunit GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0010557//positive regulation of macromolecule biosynthetic process 12797978 757.00 0.42 0.525 0.321928094887362 Up 0.0955620129441289 CG43075 CG43075 - - - - 32450 992.00 0.195 0.22 0.174029399775049 Up 0.0510500594373266 CG5662 CG5662, isoform B - GO:0031966//mitochondrial membrane - - 32230 3211.33 30.025 29.51 -0.0249603251609893 Down 0.0832452780346057 CG3812 CG3812, isoform C K13509|1|2e-157|556|dme:Dmel_CG3812|lysophosphatidate acyltransferase [EC:2.3.1.51] GO:0044464//cell part;GO:0044464//cell part GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process 40129 3770.70 50.17 51.01 0.0239551626326462 Up 0.0874389116365077 Shal shaker cognate l, isoform C K05321|1|0.0|883|dse:Dsec_GM17707|potassium voltage-gated channel Shal-related subfamily D, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0015271//outward rectifier potassium channel activity;GO:0005488//binding;GO:0015271//outward rectifier potassium channel activity GO:0030001//metal ion transport;GO:0030001//metal ion transport 37314 811.92 382.865 946.345 1.30553044831746 Up 0.76182142385418 CG18067 CG18067, isoform B - - - - 40141 1155.68 17.03 16.65 -0.0325562577199181 Down 0.091566503764364 asf1 anti-silencing factor 1, isoform B K10753|1|2e-126|452|dme:Dmel_CG9383|histone chaperone ASF1 GO:0016585//chromatin remodeling complex;GO:0016585//chromatin remodeling complex GO:0005488//binding;GO:0005488//binding GO:0043484//regulation of RNA splicing;GO:0007049//cell cycle;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0034728//nucleosome organization;GO:0043484//regulation of RNA splicing;GO:0007049//cell cycle;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0034728//nucleosome organization 43248 1052.00 0.515 3.835 2.89658224031971 Up 0.620393607185312 CG17192 CG17192 K01046|1|3e-149|527|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|1|3e-149|527|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32];K01059|2|4e-36|152|dme:Dmel_CG4582|lipoprotein lipase [EC:3.1.1.34] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 117498 1170.00 0.17 0.05 -1.76553474636298 Down 0.123794743098666 Gr22e gustatory receptor 22e K08471|1|0.0|684|dme:Dmel_CG31936|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 40126 1595.13 4.265 5.65 0.40570512598426 Up 0.34117025492009 Rcd7 reduction in Cnn dots 7, isoform B - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 33520 871.00 12.95 15.775 0.284687907295995 Up 0.39469686963413 cnir cornichon related - GO:0044464//cell part - GO:0023033;GO:0006810//transport 37105 889.00 0.37 0.54 0.545434136534519 Up 0.123827763835689 GstE10 glutathione S transferase E10, isoform B K00799|1|2e-135|481|dme:Dmel_CG17522|glutathione S-transferase [EC:2.5.1.18] - - - 5740294 2642.82 16.51 16.39 -0.0105242658137993 Down 0.0563994188350284 CG41520 CG41520, isoform D K10104|1|9e-50|198|bfo:BRAFLDRAFT_252169|ficolin;K05467|2|3e-49|197|bta:617915|angiopoietin 4 - GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0023060;GO:0023060;GO:0023060;GO:0023060 32938 3081.89 78.845 63.97 -0.301623785336054 Down 0.512481838594637 Pfrx 6-phosphofructo-2-kinase, isoform N K00900|1|0.0|1237|dme:Dmel_CG3400|6-phosphofructo-2-kinase [EC:2.7.1.105];K01103|1|0.0|1237|dme:Dmel_CG3400|fructose-2,6-bisphosphatase [EC:3.1.3.46] - GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559;GO:0008443//phosphofructokinase activity;GO:0019203//carbohydrate phosphatase activity;GO:0032559 GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process;GO:0006000//fructose metabolic process 31190 533.37 170.985 170.735 -0.00211093190079524 Down 0.0466252806762647 CG3621 CG3621, isoform B K03951|1|2e-54|211|dme:Dmel_CG3621|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 7 [EC:1.6.5.3 1.6.99.3] - - - 37268 732.00 5.76 6.44 0.160991876672305 Up 0.192510896843218 CG8517 CG8517 K03671|1|3e-80|297|dme:Dmel_CG8517|thioredoxin 1 - - - 12798271 584.00 0.08 0.01 -3 Down 0.110718531237617 31322 7668.00 2.31 2.935 0.345467651693995 Up 0.225894861973319 CG32791 CG32791, isoform C K06774|1|4e-28|127|ecb:100064766|neurotrimin - - - 34445 3785.55 10.43 10.69 0.0355226952007251 Up 0.0883634922731475 Myo31DF myosin 31DF, isoform C K10356|1|0.0|2028|dme:Dmel_CG7438|myosin I GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0016887//ATPase activity;GO:0032559;GO:0016887//ATPase activity;GO:0032559;GO:0016887//ATPase activity;GO:0032559 GO:0009888//tissue development;GO:0009855//determination of bilateral symmetry;GO:0009888//tissue development;GO:0009855//determination of bilateral symmetry;GO:0009888//tissue development;GO:0009855//determination of bilateral symmetry 19835016 1660.00 6.59 5.665 -0.218202509187536 Down 0.240820235107648 - CG45100 - - - - 34056 713.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG14538 CG14538 - - - - 41843 1938.69 43.585 42.035 -0.0522406364648665 Down 0.145192180689473 eIF-2gamma eukaryotic initiation factor 2gamma, isoform D K03242|1|0.0|894|der:Dere_GG20759|translation initiation factor eIF-2 gamma subunit;K11419|3|0.0|764|dpo:Dpse_GA19622|histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43] - - - 34542 4795.51 11.21 11.25 0.00513872329897256 Up 0.0472856954167217 Reps reps, isoform B K12483|1|1e-07|60.1|api:100166389|EH domain-containing protein 1;K12472|3|4e-07|58.2|gga:424633|epidermal growth factor receptor substrate 15 - - - 19835609 494.00 0.09 0.1 0.15200309344505 Up 0.045238409721305 31309 6364.96 32.905 36.235 0.139077072455646 Up 0.296889446572447 dnc dunce, isoform U K01120|1|0.0|999|dme:Dmel_CG32498|3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17] - - - 43114 1038.00 0.04 0.21 2.39231742277876 Up 0.155890899484876 CG4956 CG4956 - - GO:0046914//transition metal ion binding - 32529 1499.75 13.155 13.585 0.0464033170560857 Up 0.110718531237617 Paf-AHalpha Platelet-activating factor acetylhydrolase alpha, isoform B K01062|1|1e-130|466|dme:Dmel_CG8962|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity - 33477 5335.38 16.61 9.73 -0.771540363181265 Down 0.608803328490292 Duox dual oxidase, isoform C K13411|1|0.0|1176|spu:588656|dual oxidase [EC:1.6.3.1 1.11.1.-] GO:0031224//intrinsic to membrane GO:0030554//adenyl nucleotide binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity GO:0010033//response to organic substance;GO:0007166//cell surface receptor signaling pathway;GO:0007275//multicellular organismal development;GO:0006950//response to stress;GO:0008152//metabolic process 32128 1035.00 40.71 32.65 -0.318300229706217 Down 0.502476555276714 CG9360 CG9360 K11539|1|2e-16|86.7|dre:402954|carbonyl reductase 4 [EC:1.1.1.-];K11166|2|3e-15|82.4|cfa:479531|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 33365 1154.00 0.995 1.04 0.0638150975974434 Up 0.0554748381983886 CG7295 CG7295, isoform B - - GO:0005506//iron ion binding - 37631 2228.00 6.275 6.87 0.130694639979965 Up 0.169627526086382 fd59A forkhead domain 59A K09397|1|0.0|746|dme:Dmel_CG3668|forkhead box protein D GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0016564//transcription repressor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048675//axon extension;GO:0021782//glial cell development 5740126 951.00 0.535 0.565 0.0787119760140405 Up 0.0499273543785497 CG34287 CG34287 - - - - 19836042 383.00 1.925 0.675 -1.51189903853143 Down 0.408004226654339 34904 707.00 0.84 1.315 0.646601566513542 Up 0.219686963413023 CG15258 CG15258 - - - - 34098 459.55 962.85 1030.14 0.0974574517301041 Up 0.266774534407608 RpL36A ribosomal protein L36A, isoform B K02929|1|5e-48|189|dya:Dyak_GE11210|large subunit ribosomal protein L44e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 19835779 691.00 3.41 3.23 -0.0782375743302475 Down 0.0860850614185709 19835696 1583.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 45285 2552.00 3.2 4.24 0.405992359675837 Up 0.298342359001453 Dr drop K09341|1|2e-146|520|dme:Dmel_CG1897|homeobox protein MSX GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007417//central nervous system development;GO:0007447//imaginal disc pattern formation;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0010001//glial cell differentiation;GO:0006351//transcription, DNA-dependent;GO:0001708//cell fate specification 19834731 769.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 41229 1002.00 24.97 25.795 0.0468956252244618 Up 0.131521595562013 CG12811 CG12811 - - - - 14462794 524.00 0.165 0.18 0.125530882083859 Up 0.0444459120327566 36243 5934.66 49.87 47.17 -0.0803026021355172 Down 0.203440760797781 CG9005 CG9005, isoform C - - - - 19835228 931.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 44100 3265.05 22.4 26.77 0.257118406695811 Up 0.41866992471272 Patj patj, isoform C K06095|1|1e-65|252|mmu:17475|multiple PDZ domain protein GO:0043296//apical junction complex;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0015630//microtubule cytoskeleton;GO:0012505//endomembrane system;GO:0043296//apical junction complex;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0015630//microtubule cytoskeleton;GO:0012505//endomembrane system;GO:0043296//apical junction complex;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0015630//microtubule cytoskeleton;GO:0012505//endomembrane system GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007043//cell-cell junction assembly;GO:0042461//photoreceptor cell development;GO:0007163//establishment or maintenance of cell polarity;GO:0008105//asymmetric protein localization;GO:0001738//morphogenesis of a polarized epithelium;GO:0043954//cellular component maintenance;GO:0007043//cell-cell junction assembly;GO:0042461//photoreceptor cell development;GO:0007163//establishment or maintenance of cell polarity;GO:0008105//asymmetric protein localization;GO:0001738//morphogenesis of a polarized epithelium;GO:0043954//cellular component maintenance;GO:0007043//cell-cell junction assembly;GO:0042461//photoreceptor cell development;GO:0007163//establishment or maintenance of cell polarity;GO:0008105//asymmetric protein localization;GO:0001738//morphogenesis of a polarized epithelium;GO:0043954//cellular component maintenance 39847 897.00 25.75 25.74 -0.000560378737241162 Down 0.0401862369568089 Syx8 syntaxin 8 K08501|1|2e-120|432|dme:Dmel_CG4109|syntaxin 8 GO:0016020//membrane - GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis 41768 4293.48 18.59 21.36 0.200384876768072 Up 0.343118478404438 CG7987 CG7987, isoform B K09228|1|2e-60|234|bta:512364|KRAB domain-containing zinc finger protein - - - 12798257 467.00 26.365 17.75 -0.570804972100426 Down 0.596255448421609 CG13639 CG13639 - - - - 34314 890.00 68.66 54.35 -0.337189822042585 Down 0.539657905164443 CG5885 CG5885 K13251|1|3e-103|374|dme:Dmel_CG5885|translocon-associated protein subunit gamma GO:0071256;GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0048500//signal recognition particle - GO:0006612//protein targeting to membrane 42680 3742.00 2.965 2.575 -0.203459672475423 Down 0.155032360322282 Nup133 nucleoporin 133kD - - GO:0005488//binding - 43521 1531.00 6.48 6.225 -0.0579199759291816 Down 0.0956940958922203 Vps16B vacuolar protein sorting 16B - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - 318716 764.00 2.105 2.53 0.265317151627914 Up 0.171509708096685 CG31407 CG31407, isoform B - - - - 42396 1018.26 46.815 36.71 -0.350797743540819 Down 0.531435741645754 CG4390 CG4390, isoform B K01070|1|0.0|657|dsi:Dsim_GD20081|S-formylglutathione hydrolase [EC:3.1.2.12] GO:0031410//cytoplasmic vesicle;GO:0031410//cytoplasmic vesicle GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity - 10178820 501.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 CG42704 CG42704 - - - - 37801 1325.00 4.42 2.95 -0.583331415142228 Down 0.373662660150575 CG2812 CG2812 K12857|1|7e-19|95.1|bfo:BRAFLDRAFT_276603|Prp8 binding protein - - - 36574 2700.00 63.87 63.285 -0.0132748622329431 Down 0.0672302205785233 VGAT vesicular GABA transporter - GO:0031224//intrinsic to membrane - - 42364 1418.00 32.795 31.05 -0.0788826066089473 Down 0.191718399154669 Arc42 Arc42 K00248|1|0.0|712|dme:Dmel_CG4703|butyryl-CoA dehydrogenase [EC:1.3.99.2] GO:0043234//protein complex GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0030554//adenyl nucleotide binding;GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis 50188 691.00 23.205 25.765 0.150976894982837 Up 0.294677057191917 CG15386 CG15386 - - - - 19835331 451.00 0.105 0.13 0.308122295362332 Up 0.053394531765949 32459 2344.00 0.16 0.09 -0.830074998557688 Down 0.0879012019548276 dah discontinuous actin hexagon, isoform B K10366|1|7e-13|76.3|bfo:BRAFLDRAFT_125744|dystrophin GO:0044425//membrane part GO:0046914//transition metal ion binding GO:0007275//multicellular organismal development 19835462 1115.00 0.04 0.08 1 Up 0.0725795799762251 36169 707.00 0.815 0.08 -3.34872815423108 Down 0.365374455157839 CG13231 CG13231 - - - - 39520 2500.00 19.925 18.51 -0.10627482900726 Down 0.218035926561881 CG10083 actin binding protein 1 K06106|1|4e-17|90.5|dvi:Dvir_GJ10159|cortactin GO:0043232 GO:0008092//cytoskeletal protein binding GO:0048870//cell motility 246447 926.00 0.345 0.15 -1.20163386116965 Down 0.150112270505878 CG30088 CG30088 K01312|1|3e-32|138|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01310|2|2e-30|132|dre:562139|chymotrypsin [EC:3.4.21.1];K01362|3|2e-29|129|dme:Dmel_CG4920| [EC:3.4.21.-];K09620|4|2e-28|125|mmu:56538|kallikrein 11 [EC:3.4.21.-];K08667|5|9e-28|124|cfa:476402|kallikrein 6 (neurosin, zyme) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37697 780.71 13.49 12.515 -0.108232057259936 Down 0.19323735305772 CG3500 CG3500, isoform B - - - - 40714 1649.00 51.82 43.66 -0.247196885189303 Down 0.445912032756571 jagn jagunal, isoform B - GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane - GO:0016192//vesicle-mediated transport;GO:0048869//cellular developmental process;GO:0006996//organelle organization;GO:0007423//sensory organ development;GO:0009887//organ morphogenesis;GO:0007017//microtubule-based process;GO:0003006//developmental process involved in reproduction;GO:0007028//cytoplasm organization;GO:0051649//establishment of localization in cell;GO:0007300//ovarian nurse cell to oocyte transport;GO:0016192//vesicle-mediated transport;GO:0048869//cellular developmental process;GO:0006996//organelle organization;GO:0007423//sensory organ development;GO:0009887//organ morphogenesis;GO:0007017//microtubule-based process;GO:0003006//developmental process involved in reproduction;GO:0007028//cytoplasm organization;GO:0051649//establishment of localization in cell;GO:0007300//ovarian nurse cell to oocyte transport 19835063 1705.00 6.26 14.27 1.18875077254315 Up 0.657244749702813 32167 1251.00 45.38 45.64 0.00824218261634415 Up 0.0628714832915071 CG15735 CG15735 - - - - 35344 1544.02 124.465 137.785 0.146678728863691 Up 0.346123365473517 CG9328 CG9328, isoform B - - - - 3354965 1784.80 43.01 32.55 -0.402014587891652 Down 0.55583806630564 CG40160 CG40160, isoform H K01312|1|5e-35|149|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09632|2|2e-34|147|mdo:100021711|chymotrypsin-like protease [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 19834983 244.00 0.4 0.44 0.137503523749935 Up 0.0587769119006736 34284 5102.37 86.87 89.94 0.0501048464810551 Up 0.153579447893277 Pka-C1 cAMP-dependent protein kinase 1, isoform D K04345|1|0.0|733|dya:Dyak_GE10413|protein kinase A [EC:2.7.11.11] GO:0016020//membrane;GO:0043234//protein complex;GO:0016020//membrane;GO:0043234//protein complex GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559 GO:0007626//locomotory behavior;GO:0007017//microtubule-based process;GO:0007613//memory;GO:0030534//adult behavior;GO:0045450//bicoid mRNA localization;GO:0007478//leg disc morphogenesis;GO:0007227//signal transduction downstream of smoothened;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0042749//regulation of circadian sleep/wake cycle;GO:0044087;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0051969;GO:0007447//imaginal disc pattern formation;GO:0008589//regulation of smoothened signaling pathway;GO:0007472//wing disc morphogenesis;GO:0007626//locomotory behavior;GO:0007017//microtubule-based process;GO:0007613//memory;GO:0030534//adult behavior;GO:0045450//bicoid mRNA localization;GO:0007478//leg disc morphogenesis;GO:0007227//signal transduction downstream of smoothened;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0042749//regulation of circadian sleep/wake cycle;GO:0044087;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0051969;GO:0007447//imaginal disc pattern formation;GO:0008589//regulation of smoothened signaling pathway;GO:0007472//wing disc morphogenesis 34355 1761.00 9.935 4.1 -1.27689605774422 Down 0.63333773609827 CG5731 CG5731 K01204|1|0.0|873|dme:Dmel_CG5731|alpha-N-acetylgalactosaminidase [EC:3.2.1.49];K01189|5|5e-146|518|dpo:Dpse_GA20753|alpha-galactosidase [EC:3.2.1.22] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process 32330 3113.00 26.855 25.96 -0.0489003381563952 Down 0.133271694624224 CG9941 CG9941 K10604|1|9e-96|352|mdo:100019390|E3 ubiquitin-protein ligase MGRN1 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 35866 4589.54 42.575 40.845 -0.0598470468009526 Down 0.164014000792498 CG8740 CG8740, isoform E K13171|1|6e-06|54.3|gga:428216|serine/arginine repetitive matrix protein 1;K13172|2|8e-06|53.9|mdo:100018249|serine/arginine repetitive matrix protein 2 - - - 33228 1532.00 11.81 8.58 -0.460959411897612 Down 0.472691850482103 nAcRbeta-21C nicotinic acetylcholine receptor beta3 K05312|1|1e-34|147|spu:581710|nicotinic acetylcholine receptor, invertebrate;K04806|4|2e-33|143|gga:395606|nicotinic acetylcholine receptor alpha-4;K04804|5|5e-33|142|gga:395607|nicotinic acetylcholine receptor alpha-2 (neuronal) GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 38870 760.00 276.8 346.455 0.323824034228047 Up 0.551479329018624 CG7409 CG7409 K09542|1|6e-15|80.9|dme:Dmel_CG4533|crystallin, alpha B;K09541|3|4e-12|71.6|xla:378668|crystallin, alpha A GO:0015630//microtubule cytoskeleton GO:0005515//protein binding GO:0010259//multicellular organismal aging;GO:0006950//response to stress 39245 840.00 0.105 0.115 0.131244533278252 Up 0.0444459120327566 Elo68beta elongase 68beta K10249|1|2e-159|561|dme:Dmel_CG11801|elongation of very long chain fatty acids protein 4 GO:0031224//intrinsic to membrane GO:0004312//fatty acid synthase activity GO:0042446//hormone biosynthetic process;GO:0030497//fatty acid elongation 12798309 360.00 1.31 1.345 0.038039361019174 Up 0.050752872804121 CG43350 CG43350, isoform B - - - - 45278 5681.65 51.485 66.615 0.371694903375835 Up 0.558149517897239 csw corkscrew, isoform D K07293|1|0.0|1139|dme:Dmel_CG3954|protein tyrosine phosphatase, non-receptor type 11 [EC:3.1.3.48] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding GO:0042478//regulation of eye photoreceptor cell development;GO:0007417//central nervous system development;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0060446//branching involved in open tracheal system development;GO:0007049//cell cycle;GO:0042478//regulation of eye photoreceptor cell development;GO:0007417//central nervous system development;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0060446//branching involved in open tracheal system development;GO:0007049//cell cycle;GO:0042478//regulation of eye photoreceptor cell development;GO:0007417//central nervous system development;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0060446//branching involved in open tracheal system development;GO:0007049//cell cycle 34075 1346.00 2.24 2.84 0.342392197447078 Up 0.221172896579052 TwdlE TweedleE - - - - 43035 1045.00 58.095 36.985 -0.651473726301829 Down 0.655791837273808 CG11852 CG11852 K12347|1|1e-10|67.0|dan:Dana_GF18523|natural resistance-associated macrophage protein - - - 246416 2796.00 0.055 0.065 0.241008099503795 Up 0.0461960110949676 CG30049 CG30049 - - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 19834850 393.00 8.04 8.655 0.10633831818771 Up 0.163749834896315 37372 474.00 10.665 10.785 0.0161422108198825 Up 0.0611544049663188 CG9344 CG9344 K12625|1|4e-40|163|dya:Dyak_GE12153|U6 snRNA-associated Sm-like protein LSm6 - - - 42357 2172.43 41.91 46.87 0.161370273348405 Up 0.335853916259411 CG4662 CG4662, isoform F - - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - 5740235 5015.68 26.31 34.8 0.403476057570201 Up 0.544412891295734 RhoGAP1A Rho GTPase activating protein at 1A, isoform F K08878|1|1e-78|295|cin:100176232|breakpoint cluster region protein [EC:2.7.11.1] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 40174 3041.00 74.985 43.855 -0.773860691025214 Down 0.687689869237881 Rpn1 regulatory particle non-ATPase 1 K03028|1|0.0|1535|dme:Dmel_CG7762|26S proteasome regulatory subunit N1 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0009894;GO:0007052//mitotic spindle organization 326261 1188.00 0.035 0.15 2.09953567355091 Up 0.1267335886937 Spn28Db serpin 28Db K13963|1|4e-56|218|dan:Dana_GF13146|serpin B - GO:0004866//endopeptidase inhibitor activity - 246437 703.00 0.115 0.13 0.176877762084079 Up 0.0511161009113723 CG30075 CG30075 K09572|1|2e-25|115|dpo:Dpse_GA18393|FK506-binding protein 6 [EC:5.2.1.8] GO:0044424//intracellular part - GO:0044267//cellular protein metabolic process 33126 1692.00 0.025 0.085 1.76553474636298 Up 0.0883304715361247 Ir20a ionotropic receptor 20a - - - - 41265 3860.00 1.615 2.545 0.65613149138177 Up 0.307158895786554 jumu jumeau K09407|1|2e-46|188|isc:IscW_ISCW008179|forkhead box protein N GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005700//polytene chromosome GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006351//transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0010468//regulation of gene expression;GO:0051276//chromosome organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0008104//protein localization;GO:0001709//cell fate determination;GO:0006997//nucleus organization;GO:0007472//wing disc morphogenesis 10178880 1001.00 1.005 1.08 0.10383581098454 Up 0.0638951261392154 CG42853 CG42853 - - - - 39594 3437.81 9.105 7.365 -0.305973491940989 Down 0.349887729494122 RecQ5 homolog of RecQ, isoform C K10902|1|0.0|1450|dpo:Dpse_GA18497|ATP-dependent DNA helicase Q5 [EC:3.6.1.-] - GO:0032561//guanyl ribonucleotide binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559;GO:0032561//guanyl ribonucleotide binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559;GO:0032561//guanyl ribonucleotide binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle 43408 2127.00 12.15 14.705 0.275350470393921 Up 0.383998150838727 CG14529 CG14529 K01415|1|9e-100|364|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|3e-54|213|dwi:Dwil_GK15832|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43794 5261.41 80.035 91.86 0.198805742508635 Up 0.409820367190596 Asator asator, isoform L K08815|1|0.0|1788|dme:Dmel_CG11533|tau tubulin kinase [EC:2.7.11.26] - - - 7354432 1507.00 4.845 4.92 0.0221616499241587 Up 0.0542200501915203 CG42231 CG42231 - - - - 38637 864.00 8.82 9.315 0.0787771133841172 Up 0.135153876634526 Eaf6 Eaf6 K11344|1|2e-98|358|dme:Dmel_CG12756|chromatin modification-related protein EAF6 GO:0043189//H4/H2A histone acetyltransferase complex - - 326127 1270.00 5.785 4.3 -0.42798029951803 Down 0.353949280147933 CG31223 CG31223 - - - - 34032 4836.68 32.725 36.295 0.149377624038227 Up 0.31128648791441 Rapgap1 Rap GTPase activating protein 1, isoform I K08013|1|5e-59|230|mmu:20469|signal-induced proliferation-associated gene 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0009966//regulation of signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0009966//regulation of signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0009966//regulation of signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0009966//regulation of signal transduction;GO:0007264//small GTPase mediated signal transduction 318050 1382.00 0.585 0.71 0.279382399921277 Up 0.0949346189406948 CG32483 CG32483 K01289|1|0.0|890|dme:Dmel_CG32483|carboxypeptidase [EC:3.4.16.-];K09646|2|0.0|880|dsi:Dsim_GD13517|serine carboxypeptidase 1 [EC:3.4.16.-] - GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process 36854 1637.78 12.24 10.27 -0.253167376374457 Down 0.338066305639942 Cdk4 Cyclin-dependent kinase 4, isoform E K02089|1|0.0|641|dme:Dmel_CG5072|cyclin-dependent kinase 4 [EC:2.7.11.22];K02091|5|2e-75|283|tgu:100229620|cyclin-dependent kinase 6 [EC:2.7.11.22] - - - 50172 495.00 17.66 6.64 -1.41123019630154 Down 0.692742042002378 CG15024 CG15024 - - - - 34493 1379.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 CG6508 CG6508 K01379|1|0.0|834|dme:Dmel_CG6508|cathepsin D [EC:3.4.23.5];K06002|1|0.0|834|dme:Dmel_CG6508|pepsin A [EC:3.4.23.1] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35925 2385.00 9.15 8.565 -0.0953184970874056 Down 0.15407475894862 Mys45A mystery 45A - GO:0031981//nuclear lumen - GO:0022613//ribonucleoprotein complex biogenesis 40464 11460.05 30.57 34.96 0.193588632613628 Up 0.363426231673491 Ten-m tenascin major, isoform E K06252|1|4e-64|248|rno:116640|tenascin GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0004620//phospholipase activity;GO:0016740//transferase activity;GO:0048037//cofactor binding;GO:0004620//phospholipase activity;GO:0016740//transferase activity;GO:0048037//cofactor binding GO:0065008;GO:0044238//primary metabolic process;GO:0042051//compound eye photoreceptor development;GO:0007365//periodic partitioning;GO:0065008;GO:0044238//primary metabolic process;GO:0042051//compound eye photoreceptor development;GO:0007365//periodic partitioning 35923 2443.00 25.565 17.745 -0.526757451625999 Down 0.579646017699115 Pmm45A phosphomannomutase 45A K01840|1|0.0|1281|dme:Dmel_CG8073|phosphomannomutase [EC:5.4.2.8];K01835|4|0.0|697|aag:AaeL_AAEL001480|phosphoglucomutase [EC:5.4.2.2] - GO:0046872//metal ion binding;GO:0016868//intramolecular transferase activity, phosphotransferases GO:0044238//primary metabolic process 39501 1669.70 8.33 8.715 0.0651841687601375 Up 0.116067890635319 CG10171 CG10171, isoform B - - - - 50403 896.00 3.935 3.28 -0.262667820889403 Down 0.212224276845859 CG12659 CG12659 - - - - 43031 2363.00 5.545 4.59 -0.272693306747902 Down 0.259179764892352 CG11851 CG11851 K03846|1|0.0|1274|dme:Dmel_CG11851|alpha-1,2-mannosyltransferase [EC:2.4.1.-] GO:0005789//endoplasmic reticulum membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006497//protein lipidation 35077 3801.56 24.5 21.24 -0.205997983085779 Down 0.361742174085326 rdo reduced ocelli, isoform B K06260|1|1e-31|139|gga:768872|platelet glycoprotein V;K13023|3|2e-28|129|ecb:100069043|carboxypeptidase N regulatory subunit - GO:0005488//binding GO:0035214//eye-antennal disc development 39732 6754.97 22.475 31.87 0.503877903376043 Up 0.584929335622771 sff sugar-free frosting, isoform C K08796|1|0.0|1414|dme:Dmel_CG6114|BR serine/threonine kinase [EC:2.7.11.1] GO:0043005//neuron projection GO:0004672//protein kinase activity;GO:0032559 GO:0016192//vesicle-mediated transport;GO:0043062//extracellular structure organization;GO:0006468//protein phosphorylation;GO:0001558//regulation of cell growth;GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0008104//protein localization 38000 2651.17 66.115 49.315 -0.422951090078733 Down 0.583839651301017 CG3829 CG3829, isoform B K12384|1|6e-55|216|dre:192340|lysosome membrane protein 2;K13885|2|2e-51|204|dre:387260|scavenger receptor class B, member 1 GO:0016021//integral to membrane GO:0004888//transmembrane signaling receptor activity GO:0048102//autophagic cell death 33916 3233.29 12.4 15.06 0.280381649397691 Up 0.388588033284903 eya eyes absent, isoform C K01104|1|0.0|1001|dse:Dsec_GM14165|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0009888//tissue development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0008354//germ cell migration;GO:0010467//gene expression;GO:0001708//cell fate specification;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0009314//response to radiation;GO:0007560//imaginal disc morphogenesis;GO:0007431//salivary gland development;GO:0001743//optic placode formation;GO:0009888//tissue development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0008354//germ cell migration;GO:0010467//gene expression;GO:0001708//cell fate specification;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0009314//response to radiation;GO:0007560//imaginal disc morphogenesis;GO:0007431//salivary gland development;GO:0001743//optic placode formation 42727 2959.00 45.135 24.75 -0.866818082200159 Down 0.685675604279487 CG17111 CG17111 - - - - 32603 3646.89 48.39 53.11 0.134274590216026 Up 0.295535596354511 nonA no on or off transient A, isoform D K13219|1|0.0|674|dme:Dmel_CG4211|splicing factor, proline- and glutamine-rich GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003727//single-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003727//single-stranded RNA binding GO:0009416//response to light stimulus;GO:0000377;GO:0050953//sensory perception of light stimulus;GO:0008049//male courtship behavior;GO:0009416//response to light stimulus;GO:0000377;GO:0050953//sensory perception of light stimulus;GO:0008049//male courtship behavior;GO:0009416//response to light stimulus;GO:0000377;GO:0050953//sensory perception of light stimulus;GO:0008049//male courtship behavior 318222 404.00 0.315 0.12 -1.39231742277876 Down 0.157343811913882 CG32811 CG32811 - - - - 36487 1677.00 9.16 2.97 -1.62488466729618 Down 0.657178708228768 CG18278 CG18278 K01137|1|0.0|1038|dme:Dmel_CG18278|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14] GO:0000323//lytic vacuole GO:0008484//sulfuric ester hydrolase activity GO:0006041//glucosamine metabolic process;GO:0006022 37229 497.00 107.955 82.315 -0.391202806752875 Down 0.582056531501783 cer crammer K01376|1|1e-09|62.0|gga:420160| [EC:3.4.22.-];K01365|2|5e-09|60.1|dre:30443|cathepsin L [EC:3.4.22.15];K01371|4|8e-09|59.3|xtr:448216|cathepsin K [EC:3.4.22.38] - - - 37652 2043.00 55.905 54.34 -0.0409627542280311 Down 0.129012019548276 CG9896 CG9896 - - - - 35515 936.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 Tsp42A tetraspanin 42A, isoform B - GO:0031224//intrinsic to membrane - - 33529 2823.52 21.045 18.485 -0.187122466153812 Down 0.329447893276978 Mad mothers against dpp, isoform B K04676|1|0.0|913|dse:Dsec_GM18164|SMAD, mothers against DPP 1/5/8 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0016564//transcription repressor activity;GO:0003677//DNA binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048592//eye morphogenesis;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0045704;GO:0010551;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0007350//blastoderm segmentation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0060541//respiratory system development;GO:0007281//germ cell development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0019827//stem cell maintenance;GO:0007478//leg disc morphogenesis 117500 1185.00 0.01 0.04 2 Up 0.0694426099590543 Gr22a gustatory receptor 22a K08471|1|0.0|690|dme:Dmel_CG31662|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 36604 2027.00 8.73 9.235 0.0811303073529979 Up 0.135153876634526 Sin1 SAPK-interacting protein 1 - GO:0044444//cytoplasmic part - GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0050789//regulation of biological process;GO:0048812//neuron projection morphogenesis 31970 5086.25 6.85 9.52 0.474857585460054 Up 0.448916919825651 CG32683 CG32683, isoform B K13805|1|1e-29|133|isc:IscW_ISCW006452|arrestin-2;K04439|2|1e-28|129|tgu:100230301|beta-arrestin - - - 41502 778.07 22.105 26.975 0.287250225421313 Up 0.448751816140536 GstD9 glutathione S transferase D9, isoform B K00799|1|5e-119|426|dme:Dmel_CG10091|glutathione S-transferase [EC:2.5.1.18] - - - 19834721 1933.00 0.145 0.135 -0.103093492964104 Down 0.0433232069739797 - CG44405 - - - - 246580 1177.00 5.83 6.2 0.0887723320737413 Up 0.122771100250958 CG30381 CG30381, isoform C K07541|1|8e-126|449|dme:Dmel_CG30381|phosphatidylinositol glycan, class X - - - 3355144 409.03 990.235 984.285 -0.00869483365672793 Down 0.0708955223880597 RpL38 ribosomal protein L38, isoform B K02923|1|1e-33|140|dwi:Dwil_GK21940|large subunit ribosomal protein L38e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 40748 1038.39 0.365 0.685 0.908207524080509 Up 0.190331528199709 Vha14-2 vacuolar H[+] ATPase 14kD subunit 2, isoform C K02151|1|3e-72|270|dme:Dmel_CG1076|V-type H+-transporting ATPase subunit F [EC:3.6.3.14] GO:0033176 GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process 14462802 588.00 0.075 0.08 0.0931094043914812 Up 0.0382380134724607 7354403 846.00 18.905 18.98 0.00571214303387482 Up 0.0513802668075551 Tfb5 TFB5 ortholog K11663|1|1e-77|289|dme:Dmel_CG31917|zinc finger HIT domain-containing protein 1 - - - 37704 1341.00 62.12 22.985 -1.4343651635705 Down 0.745938449346189 yellow-d2 yellow-d2 - - - - 31278 2412.94 42.73 19.35 -1.14291575064934 Down 0.714370624752344 CG3588 CG3588, isoform I - - - - 35712 782.00 29.19 39.61 0.440390490402352 Up 0.572216351868974 CG12107 CG12107 - - - - 39191 1176.00 0.345 0.165 -1.06413033741972 Down 0.144069475630696 Or67d odorant receptor 67d K08471|1|3e-06|52.8|dpo:Dpse_GA17168|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 3772574 1675.00 3.155 5.66 0.843162047849333 Up 0.485602958658037 Fuca alpha-L-fucosidase K01206|1|0.0|1051|dme:Dmel_CG6128|alpha-L-fucosidase [EC:3.2.1.51] - GO:0043167//ion binding;GO:0015928//fucosidase activity GO:0019318//hexose metabolic process;GO:0016139//glycoside catabolic process 39683 4007.65 88.61 87.8 -0.0132485822285557 Down 0.0682208426892088 AGO2 argonaute 2, isoform E K11593|1|8e-103|375|bfo:BRAFLDRAFT_81672|eukaryotic translation initiation factor 2C GO:0031332;GO:0031332 GO:0008135//translation factor activity, nucleic acid binding;GO:0004519//endonuclease activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0004519//endonuclease activity GO:0016246//RNA interference;GO:0050658//RNA transport;GO:0007365//periodic partitioning;GO:0003006//developmental process involved in reproduction;GO:0048102//autophagic cell death;GO:0002252;GO:0001700//embryonic development via the syncytial blastoderm;GO:0070828//heterochromatin organization;GO:0045069//regulation of viral genome replication;GO:0016246//RNA interference;GO:0050658//RNA transport;GO:0007365//periodic partitioning;GO:0003006//developmental process involved in reproduction;GO:0048102//autophagic cell death;GO:0002252;GO:0001700//embryonic development via the syncytial blastoderm;GO:0070828//heterochromatin organization;GO:0045069//regulation of viral genome replication 43700 1465.00 16.605 15.245 -0.12328157249296 Down 0.224673094703474 spn-F spn-F, isoform B - - GO:0003777//microtubule motor activity GO:0007308//oocyte construction 48572 2203.00 3.225 4.36 0.43502897446631 Up 0.316371681415929 Hsp60B heat shock protein 60 related K04077|1|0.0|674|dpo:Dpse_GA22684|chaperonin GroEL GO:0031980 GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0006457//protein folding;GO:0006605//protein targeting;GO:0006950//response to stress 38969 2770.00 1.19 2.18 0.873366561468983 Up 0.334698190463611 CG6745 CG6745 K01855|1|0.0|983|dpo:Dpse_GA19828| [EC:5.4.99.-] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0009451//RNA modification 37144 1743.65 58.825 54.115 -0.12040086897403 Down 0.279487518161405 CG5482 CG5482, isoform D K09574|1|0.0|759|dme:Dmel_CG5482|FK506-binding protein 8 [EC:5.2.1.8] - - - 35621 1203.00 15.92 10.035 -0.665799719181032 Down 0.578556333377361 Tsp42Ek tetraspanin 42Ek, isoform B K06497|1|3e-07|55.5|dan:Dana_GF13154|CD63 antigen GO:0031224//intrinsic to membrane - - 32860 3192.00 2.77 3.79 0.452311872121903 Up 0.301215163122441 CCKLR-17D1 Cholecystokinin-like receptor at 17D1 K04196|1|0.0|1095|dme:Dmel_CG42301|cholecystokinin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0004951//cholecystokinin receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 40686 955.19 8.36 8.12 -0.0420232148957063 Down 0.0853255844670453 CG2911 CG2911, isoform B K09531|1|2e-08|60.1|bfo:BRAFLDRAFT_283992|DnaJ homolog subfamily C member 11;K09530|2|4e-08|58.9|cfa:478826|DnaJ homolog subfamily C member 10 - GO:0005515//protein binding;GO:0005515//protein binding - 3355129 3120.98 57.13 61.79 0.113124843519054 Up 0.264165896182803 CG17715 CG17715, isoform H - - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005488//binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005488//binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding GO:0006026;GO:0006022;GO:0006026;GO:0006026;GO:0006022;GO:0006026 38152 876.00 0.095 0.26 1.45251220469751 Up 0.140602298243297 CG9184 CG9184, isoform B - - - - 37619 4170.15 3.03 2.935 -0.0459572903628989 Down 0.0653810593052437 stl stall, isoform E K08630|1|2e-53|212|bta:520133|a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-] - GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0000904//cell morphogenesis involved in differentiation 37401 3410.02 10.46 10.775 0.042805017729519 Up 0.0944723286223749 CG4050 CG4050, isoform B K09667|1|1e-24|115|dwi:Dwil_GK21381|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - - - 41168 3972.78 16.315 15.82 -0.0444493876190723 Down 0.107977810064721 Scm Sex comb on midleg, isoform B K11461|1|0.0|1336|dme:Dmel_CG9495|polycomb protein SCMH1;K11465|2|0.0|662|aag:AaeL_AAEL007360|sex comb on midleg-like protein 2 GO:0031519//PcG protein complex GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007293//germarium-derived egg chamber formation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0010468//regulation of gene expression 39512 928.08 54.34 50.11 -0.116916027792397 Down 0.276845859199577 CG14109 CG14109, isoform B - - - - 34482 725.00 0.17 0.37 1.12199052437861 Up 0.152522784308546 Vha16-5 vacuolar H[+] ATPase 16kD subunit 5 K02155|1|1e-75|283|dme:Dmel_CG6737|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport 32367 6274.00 0.01 0.01 0 - 0.0382380134724607 yl yolkless, isoform B K06233|1|0.0|667|ecb:100062836|low density lipoprotein-related protein 2 GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane GO:0004872//receptor activity;GO:0046872//metal ion binding;GO:0004872//receptor activity;GO:0046872//metal ion binding GO:0007292//female gamete generation;GO:0007028//cytoplasm organization;GO:0007292//female gamete generation;GO:0007028//cytoplasm organization 19834818 774.00 1.725 1.51 -0.192047812340453 Down 0.113954563465857 3772084 616.00 1.645 1.61 -0.0310268956206244 Down 0.0473517368907674 CG33668 CG33668 - - - - 31019 1565.00 0.105 0.12 0.192645077942396 Up 0.045898824461762 CG13361 CG13361 - - - - 318250 2013.00 3.385 2.57 -0.397387474381118 Down 0.26436402060494 CG32855 CG32855 - - - - 246510 373.00 1.145 1.55 0.436920617177294 Up 0.187854972922996 CG30192 CG30192 - - - - 38496 1933.84 50.3 30.9 -0.702951561901153 Down 0.660513802668076 CG1299 CG1299, isoform B K01316|1|2e-42|174|rno:288291|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K01312|2|2e-41|171|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09634|4|1e-38|161|gga:427988|transmembrane protease, serine 3 [EC:3.4.21.-];K01362|5|1e-38|161|dme:Dmel_CG4920| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31208 2332.00 12.81 11.935 -0.10207190925987 Down 0.179401664245146 crn crooked neck K12869|1|0.0|1332|dme:Dmel_CG3193|crooked neck - - - 33022 1405.72 197.67 71.575 -1.46556626226052 Down 0.764925373134328 obst-A obstructor-A, isoform B K01873|1|4e-15|83.2|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K05030|5|1e-09|65.1|cin:100175971|calcium-activated chloride channel family member 4 - GO:0030247//polysaccharide binding GO:0006022 41120 634.55 538.645 555.855 0.0453738295733825 Up 0.161339321093647 RpL34b ribosomal protein L34b, isoform D K02915|1|2e-58|224|dya:Dyak_GE24782|large subunit ribosomal protein L34e GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding GO:0010467//gene expression;GO:0010467//gene expression 37006 1154.00 38.7 41.45 0.0990385353513402 Up 0.235371813498877 P32 P32 - - - - 41955 5578.76 68.78 76.61 0.155543605381924 Up 0.349029190331528 Mhcl myosin heavy chain-like, isoform I K10362|1|0.0|660|dme:Dmel_CG31045|myosin XVIII - GO:0016887//ATPase activity;GO:0000166//nucleotide binding - 33932 3391.00 19.485 21.86 0.165929469502867 Up 0.307720248315942 CG11070 CG11070 K10596|1|0.0|1858|dme:Dmel_CG11070|ubiquitin conjugation factor E4 A [EC:6.3.2.19] GO:0043234//protein complex GO:0005488//binding;GO:0004842//ubiquitin-protein ligase activity GO:0019941//modification-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation 318857 796.00 2.775 1.81 -0.616498074154263 Down 0.309206181481971 CG33082 CG33082 K03540|1|2e-77|288|dme:Dmel_CG33082|ribonuclease P subunit RPR2 [EC:3.1.26.5] - - - 32698 4399.35 10.43 11.39 0.127028589188346 Up 0.207535332188614 CG5004 CG5004, isoform E K10392|1|4e-10|68.2|cqu:CpipJ_CPIJ001696|kinesin family member 1/13/14 - - - 37459 1143.00 15.555 13.795 -0.173232938181109 Down 0.284044379870559 CG15673 CG15673 - - - - 34465 1757.14 11.315 5.42 -1.06187182791302 Down 0.620789856029587 CG17104 CG17104, isoform C - - - - 50456 812.68 3.43 5.53 0.689070904061895 Up 0.441751419891692 CG13245 CG13245, isoform C - - - - 37791 2386.00 2 2.19 0.130930869826449 Up 0.0994914806498481 DNA-ligI DNA ligase I K10747|1|0.0|1401|dme:Dmel_CG5602|DNA ligase 1 [EC:6.5.1.1] - GO:0003676//nucleic acid binding;GO:0003909//DNA ligase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress 38097 1328.48 10.44 11.275 0.111005721572859 Up 0.183364152687888 CG13902 CG13902, isoform C K01047|1|3e-15|83.2|dme:Dmel_CG10133|phospholipase A2 [EC:3.1.1.4];K00476|2|3e-14|79.7|dre:373126|aspartate beta-hydroxylase [EC:1.14.11.16] - - GO:0009987//cellular process;GO:0008152//metabolic process 35930 2121.35 32.005 32.92 0.0406670271559517 Up 0.121186104873861 Hydr1 alpha/beta hydrolase 1, isoform E K13696|1|0.0|909|dme:Dmel_CG8058|abhydrolase domain-containing protein 1/3 - GO:0016788//hydrolase activity, acting on ester bonds;GO:0016788//hydrolase activity, acting on ester bonds;GO:0016788//hydrolase activity, acting on ester bonds - 40918 1426.04 42.825 39.62 -0.112224366081875 Down 0.254721965394268 Sp7 serine protease 7, isoform F K01312|1|2e-159|561|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|4e-65|248|dpo:Dpse_GA18526| [EC:3.4.21.-];K01344|5|1e-34|147|xla:380116|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006582//melanin metabolic process;GO:0006950//response to stress;GO:0009893//positive regulation of metabolic process;GO:0019538//protein metabolic process;GO:0006582//melanin metabolic process;GO:0006950//response to stress;GO:0009893//positive regulation of metabolic process;GO:0019538//protein metabolic process;GO:0006582//melanin metabolic process;GO:0006950//response to stress;GO:0009893//positive regulation of metabolic process 36932 1606.00 22.26 21.425 -0.0551583883420971 Down 0.143243957205125 Amy-d amylase distal K01176|1|0.0|894|dme:Dmel_CG17876|alpha-amylase [EC:3.2.1.1] - - - 2768867 716.55 0.46 1.715 1.8985028101158 Up 0.420320961563862 CG33223 CG33223, isoform B - - - - 19834727 1188.00 10.38 10.49 0.0152082342193871 Up 0.0598335754854048 38153 3457.79 1.855 1.99 0.101349243922846 Up 0.0813300752872804 Myo61F myosin 61F, isoform D K10356|1|0.0|1917|dme:Dmel_CG9155|myosin I GO:0015629//actin cytoskeleton;GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0042995//cell projection GO:0016887//ATPase activity;GO:0032559;GO:0016887//ATPase activity;GO:0032559;GO:0016887//ATPase activity;GO:0032559;GO:0016887//ATPase activity;GO:0032559 GO:0006952//defense response;GO:0009888//tissue development;GO:0030030//cell projection organization;GO:0009855//determination of bilateral symmetry;GO:0006952//defense response;GO:0009888//tissue development;GO:0030030//cell projection organization;GO:0009855//determination of bilateral symmetry;GO:0006952//defense response;GO:0009888//tissue development;GO:0030030//cell projection organization;GO:0009855//determination of bilateral symmetry;GO:0006952//defense response;GO:0009888//tissue development;GO:0030030//cell projection organization;GO:0009855//determination of bilateral symmetry 41149 1750.00 18.835 18.135 -0.054639287977113 Down 0.127030775326905 CG8199 CG8199 K00166|1|0.0|894|dme:Dmel_CG8199|2-oxoisovalerate dehydrogenase E1 component, alpha subunit [EC:1.2.4.4] - GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0035337 10178813 510.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 5740391 401.00 0.85 0.24 -1.82442843541655 Down 0.299299960375116 CG34176 CG34176 - - - - 33093 4663.59 0.095 0.465 2.29123129766445 Up 0.237419099194294 unc uncoordinated, isoform B - GO:0005813//centrosome - GO:0042384//cilium assembly;GO:0050954//sensory perception of mechanical stimulus;GO:0048232//male gamete generation 19835742 950.00 4.41 7.415 0.74966803689711 Up 0.507627790252278 39224 565.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 Cpr67Fa2 cuticular protein 67Fa2 - - GO:0042302//structural constituent of cuticle - 39805 706.00 0.175 0.535 1.61218396945618 Up 0.224706115440497 CG13039 CG13039 - - - - 43202 1025.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 TwdlB TweedleB - - - - 40162 1625.00 22.02 24.785 0.170652789905958 Up 0.318220842689209 cyc cycle K02296|1|0.0|759|dme:Dmel_CG8727|aryl hydrocarbon receptor nuclear translocator-like protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0023060;GO:0007562//eclosion;GO:0007626//locomotory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0006950//response to stress;GO:0030534//adult behavior 41274 1377.00 12.1 19.065 0.655919483564158 Up 0.593349623563598 CG6465 CG6465 K01436|1|0.0|824|dme:Dmel_CG6465|aminoacylase [EC:3.5.1.14] GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0006519 41314 1116.00 0.935 2.865 1.61549686886927 Up 0.488905032360322 CG14695 CG14695 K08056|1|3e-10|66.2|dpe:Dper_GL10245|protein disulfide isomerase family A, member 3 [EC:5.3.4.1] - - - 36499 3446.37 5.44 6.62 0.283224565556878 Up 0.289558842953375 mip120 Myb-interacting protein 120, isoform B - GO:0044427//chromosomal part;GO:0044427//chromosomal part GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048870//cell motility;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0006277//DNA amplification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048870//cell motility;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0006277//DNA amplification 32351 2792.01 8.17 6.81 -0.262681280133612 Down 0.29877162858275 jub ajuba LIM protein, isoform E K12792|1|7e-57|222|rno:686323|thyroid receptor-interacting protein 6 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 39461 3292.20 25.64 30.065 0.229688696577326 Up 0.39770175670321 Ent3 equilibrative nucleoside transporter 3, isoform C K03323|1|5e-13|77.0|dme:Dmel_CG11907|equilibrative nucleoside transporter, ENT family GO:0044464//cell part GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0051234//establishment of localization 32049 4359.76 23.575 26.635 0.176065509998691 Up 0.333377360982697 Klp10A Kinesin-like protein at 10A, isoform F K10393|1|0.0|1395|dme:Dmel_CG1453|kinesin family member 2/24 GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559 GO:0000819//sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0000090//mitotic anaphase;GO:0000819//sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0000090//mitotic anaphase;GO:0000819//sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0000090//mitotic anaphase;GO:0000819//sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0000090//mitotic anaphase;GO:0000819//sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0000090//mitotic anaphase 40289 2532.00 10 10.35 0.0496307677246004 Up 0.103123761722362 CG13252 CG13252 K08706|1|5e-07|57.0|dya:Dyak_GE22392|nuclear receptor subfamily 0 group A;K06052|2|6e-07|56.6|dre:140423|jagged;K04657|3|2e-06|54.7|dwi:Dwil_GK25623|chordin - - - 33656 1278.00 10.92 13.05 0.257076950537394 Up 0.352100118874653 CG15443 CG15443, isoform B - - - - 33062 11087.85 11.075 11.15 0.0097370113652866 Up 0.0526350548144235 shakB shaking B, isoform I - GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane GO:0004872//receptor activity;GO:0022829//wide pore channel activity;GO:0004872//receptor activity;GO:0022829//wide pore channel activity;GO:0004872//receptor activity;GO:0022829//wide pore channel activity;GO:0004872//receptor activity;GO:0022829//wide pore channel activity;GO:0004872//receptor activity;GO:0022829//wide pore channel activity GO:0007043//cell-cell junction assembly;GO:0009314//response to radiation;GO:0007165//signal transduction;GO:0007043//cell-cell junction assembly;GO:0009314//response to radiation;GO:0007165//signal transduction;GO:0007043//cell-cell junction assembly;GO:0009314//response to radiation;GO:0007165//signal transduction;GO:0007043//cell-cell junction assembly;GO:0009314//response to radiation;GO:0007165//signal transduction;GO:0007043//cell-cell junction assembly;GO:0009314//response to radiation;GO:0007165//signal transduction 37172 3021.59 9.72 12.455 0.357696802635056 Up 0.424910844010038 CG15097 CG15097, isoform E K10454|1|0.0|1212|dya:Dyak_GE13880|kelch-like protein 17 (actinfilin) - GO:0005488//binding - 43269 2601.00 0.07 0.05 -0.485426827170241 Down 0.0549134856690001 CG5882 CG5882 K10352|1|1e-28|128|bmy:Bm1_51435|myosin heavy chain;K06102|4|8e-26|119|xla:398149|cingulin - - - 40956 1881.12 4.615 6.755 0.54962512167991 Up 0.429203539823009 CG7910 CG7910, isoform B K01426|1|0.0|859|dpo:Dpse_GA20678|amidase [EC:3.5.1.4];K01175|3|6e-28|125|mdo:100023944| [EC:3.1.-.-] - GO:0016879//ligase activity, forming carbon-nitrogen bonds - 19835410 576.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 14462660 354.00 0.25 0.335 0.422233000683048 Up 0.0914674415532955 CG44072 CG44072 - - - - 41757 734.00 12.815 14.135 0.141438404539598 Up 0.240291903315282 mRpL11 mitochondrial ribosomal protein L11 - - - - 19834789 595.00 31.88 38.285 0.264127627981081 Up 0.443072249372606 43753 1812.00 0.22 0.3 0.447458976971221 Up 0.0880993263769647 Ir100a ionotropic receptor 100a - - - - 19835030 601.00 0.135 0.08 -0.754887502163469 Down 0.0813630960243033 42215 571.00 20.125 21.94 0.124574742513851 Up 0.24293356227711 CG44009 CG44009, isoform B K08493|1|2e-42|171|dme:Dmel_CG31232|vesicle transport through interaction with t-SNAREs 1 - - GO:0042078//germ-line stem cell division;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 36758 956.00 24.44 23.84 -0.0358600493565679 Down 0.112237485140668 Pex11 peroxin 11 K13352|1|4e-136|424|dse:Dsec_GM20102|peroxin-11B GO:0044439 - GO:0007031//peroxisome organization 42053 1835.00 0.19 0.2 0.0740005814437768 Up 0.042365605600317 CG5225 CG5225 - - - - 42504 3492.00 25.73 27.705 0.106694909969794 Up 0.23586712455422 slmb supernumerary limbs, isoform C K03362|1|0.0|1051|dme:Dmel_CG3412|F-box and WD-40 domain protein 1/11 GO:0031461//cullin-RING ubiquitin ligase complex GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0007297//ovarian follicle cell migration;GO:0008306//associative learning;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0007067//mitosis;GO:0000904//cell morphogenesis involved in differentiation;GO:0007224//smoothened signaling pathway;GO:0006508//proteolysis;GO:0030703//eggshell formation;GO:0035466;GO:0007293//germarium-derived egg chamber formation;GO:0043066//negative regulation of apoptotic process 34634 2466.00 14.955 18.035 0.270171512668218 Up 0.397074362699775 Patsas patsas K08803|1|3e-18|94.4|spu:575268|death-associated protein kinase [EC:2.7.11.1] - GO:0046914//transition metal ion binding - 43654 3055.93 56.52 63.84 0.175699185888407 Up 0.372672038039889 cindr CIN85 and CD2AP orthologue, isoform J K12470|1|2e-15|85.1|cfa:612797|SH3 domain-containing kinase-binding protein 1 - - - 39727 1777.42 1.185 1.595 0.42866936486661 Up 0.189506009774138 CG32150 CG32150, isoform D - - GO:0005488//binding - 44540 10936.24 9.25 11.745 0.344521442608523 Up 0.407839122969225 ct cut, isoform E K09313|1|0.0|1027|dme:Dmel_CG11387|homeobox protein cut-like GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0007423//sensory organ development;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006355//regulation of transcription, DNA-dependent;GO:0008406//gonad development;GO:0050954//sensory perception of mechanical stimulus;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048598//embryonic morphogenesis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0007423//sensory organ development;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006355//regulation of transcription, DNA-dependent;GO:0008406//gonad development;GO:0050954//sensory perception of mechanical stimulus;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048598//embryonic morphogenesis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway 19988923 1392.00 0.14 0.4 1.51457317282976 Up 0.183430194161934 - aldehyde reductase Y, isoform D K00011|1|2e-74|279|dme:Dmel_CG10863|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 31003 3412.00 0.12 0.215 0.841302253980942 Up 0.0983027341170255 vnd ventral nervous system defective, isoform B K08029|1|0.0|792|dsi:Dsim_GD16514|homeobox protein Nkx-2.2 - - - 19835820 792.00 0.55 1.485 1.43295940727611 Up 0.353982300884956 37889 2581.00 0.4 0.36 -0.15200309344505 Down 0.0594703473781535 slbo slow border cells, isoform B K10052|1|1e-142|507|dme:Dmel_CG4354|CCAAT/enhancer binding protein (C/EBP), invertebrate - GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0007297//ovarian follicle cell migration;GO:0045165//cell fate commitment;GO:0006350 36831 1663.00 3.605 3.9 0.113474864508788 Up 0.117487782327302 wcd wicked K11422|1|2e-55|217|bfo:BRAFLDRAFT_125552|histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43] - - - 41363 22540.52 24.17 32.46 0.425445526782389 Up 0.554748381983886 pros prospero, isoform M - GO:0044448//cell cortex part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044448//cell cortex part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044448//cell cortex part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0016564//transcription repressor activity GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0007409//axonogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0050767//regulation of neurogenesis;GO:0042675//compound eye cone cell differentiation;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0007409//axonogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0010468//regulation of gene expression;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0050767//regulation of neurogenesis;GO:0042675//compound eye cone cell differentiation;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0007417//central nervous system development;GO:0014017//neuroblast fate commitment;GO:0007409//axonogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0010468//regulation of gene expression;GO:0007405//neuroblast proliferation;GO:0051301//cell division;GO:0050767//regulation of neurogenesis;GO:0042675//compound eye cone cell differentiation;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior 3772181 552.00 1.96 3.705 0.918619888190626 Up 0.434486857746665 CG33784 CG33784 K09255|1|7e-10|63.2|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|1e-09|62.4|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 246496 478.40 121.335 134.545 0.149093011320043 Up 0.34592524105138 CG30172 CG30172, isoform B - - - - 40522 3539.72 49.42 35.46 -0.478902474430096 Down 0.599128252542597 CG12581 CG12581, isoform B - - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 37939 875.59 1.705 1.705 0 - 0.0382380134724607 CG4741 CG4741, isoform C - - - - 42137 7233.94 15.73 15.985 0.0232000733648335 Up 0.0730088495575221 CG43102 CG43102, isoform G K04436|1|2e-23|111|xtr:100170186|mitogen-activated protein kinase 8 interacting protein 3 - - - 32081 669.49 52.81 58.255 0.141570739527196 Up 0.313168669924713 Tim8 Tim8, isoform B K10836|1|7e-46|183|dme:Dmel_CG1728|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 35296 1541.00 13.465 14.37 0.0938458319556645 Up 0.17388720116233 CG10721 CG10721, isoform B - - - - 37842 1117.00 162.475 165.595 0.0274413645639315 Up 0.113690397569674 gammaSnap gamma soluble NSF attachment protein 1 - GO:0043231//intracellular membrane-bounded organelle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006691//leukotriene metabolic process;GO:0015031//protein transport 39159 1972.22 9.135 10.305 0.173867870911768 Up 0.247193237353058 CG10809 CG10809, isoform B K12271|1|3e-16|87.0|mdo:100012228|signal recognition particle 43 kDa protein;K06694|2|3e-12|73.9|gga:422351|26S proteasome non-ATPase regulatory subunit 10 - - GO:0009987//cellular process;GO:0009987//cellular process 31830 1143.72 0.565 0.795 0.492703992869168 Up 0.141658961828028 CG10970 CG10970, isoform B K01512|1|5e-51|202|dme:Dmel_CG10970|acylphosphatase [EC:3.6.1.7] - - - 19834857 403.00 0.55 0.54 -0.0264722113611911 Down 0.0416391493858143 19834780 521.41 3.835 2.705 -0.503597983676118 Down 0.322414476291111 35761 7845.29 90.85 81.715 -0.152885583710448 Down 0.339981508387267 ACC Acetyl-CoA carboxylase, isoform G K11262|1|0.0|4655|dse:Dsec_GM20735|acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding;GO:0016421//CoA carboxylase activity;GO:0032559;GO:0019842//vitamin binding;GO:0016421//CoA carboxylase activity;GO:0032559;GO:0019842//vitamin binding;GO:0016421//CoA carboxylase activity;GO:0032559;GO:0019842//vitamin binding;GO:0016421//CoA carboxylase activity;GO:0032559 GO:0006631//fatty acid metabolic process;GO:0010468//regulation of gene expression;GO:0006631//fatty acid metabolic process;GO:0010468//regulation of gene expression;GO:0006631//fatty acid metabolic process;GO:0010468//regulation of gene expression;GO:0006631//fatty acid metabolic process;GO:0010468//regulation of gene expression 36121 3405.46 25.895 27.845 0.104744734166163 Up 0.222790912693171 CG11883 CG11883, isoform D K01081|1|0.0|1261|dme:Dmel_CG11883|5'-nucleotidase [EC:3.1.3.5] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 35804 815.58 1.535 1.93 0.330362191897901 Up 0.178609166556598 CG2291 CG2291, isoform B - - - - 31807 1291.00 6.475 7.665 0.243405599084861 Up 0.276581693303395 CG11294 CG11294, isoform B K12373|1|3e-37|155|nvi:100119475|beta-hexosaminidase [EC:3.2.1.52];K09451|2|3e-17|89.4|spu:580069|homeobox protein aristaless-like 4;K09334|5|2e-16|86.7|xla:373650|cartilage homeoprotein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 35427 3433.00 1.1 0.905 -0.281513826441454 Down 0.118676528860124 CG31612 CG31612, isoform B K09228|1|2e-39|164|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 43895 4451.17 3.065 3.04 -0.0118157502471961 Down 0.0453704926693964 E23 early gene at 23, isoform E K05681|1|4e-58|227|spu:584842|ATP-binding cassette, subfamily G (WHITE), member 2;K05679|3|1e-54|216|bfo:BRAFLDRAFT_82876|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0050789//regulation of biological process;GO:0050789//regulation of biological process;GO:0050789//regulation of biological process 326145 1030.00 0.19 0.38 1 Up 0.14816404702153 CG31496 CG31496 - - - - 36985 635.00 725.24 693.585 -0.0643857998335259 Down 0.185015189539031 RpL18A ribosomal protein L18A K02882|1|4e-100|363|dya:Dyak_GE13987|large subunit ribosomal protein L18Ae - - - 39839 828.00 0.16 0.215 0.426264754702098 Up 0.073702285035002 CG13033 CG13033 - - - - 317897 2276.00 1.33 1.505 0.178337241258512 Up 0.103090740985339 CG32181 CG32181 - - - - 34079 2193.32 0.525 0.61 0.216491819896764 Up 0.080537577598732 CG7102 CG7102, isoform B K10481|1|3e-17|90.5|bfo:BRAFLDRAFT_93002|BTB/POZ domain-containing protein 9 - GO:0005488//binding - 40159 976.22 13.625 16.815 0.303492548974932 Up 0.418702945449742 CG15881 CG15881, isoform C - - GO:0003676//nucleic acid binding - 32412 2085.00 0.13 0.065 -1 Down 0.0856557918372738 CG12539 CG12539 K00115|1|0.0|1201|dme:Dmel_CG12539|glucose dehydrogenase (acceptor) [EC:1.1.99.10];K00108|2|6e-133|474|dme:Dmel_CG9519|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 39499 1160.00 0.83 3.84 2.20992306937423 Up 0.582551842557126 ImpL1 Ecdysone-inducible gene L1, isoform C - - - - 43764 1954.00 47.235 45.22 -0.062895266105037 Down 0.1670519085986 mod modulo, isoform C K13091|1|2e-08|61.2|tgu:100229956|RNA-binding protein 39 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003677//DNA binding;GO:0003723//RNA binding GO:0007281//germ cell development 43832 8339.19 36.865 39.97 0.116665815788635 Up 0.268029322414476 plexA plexin A, isoform F K06820|1|0.0|3029|dya:Dyak_GE14494|plexin A - - - 41476 1427.00 1.465 1.865 0.34827496583299 Up 0.180293224144763 CG3809 CG3809 K00856|1|0.0|806|dme:Dmel_CG3809|adenosine kinase [EC:2.7.1.20] - - - 43827 10386.46 284.11 258.855 -0.134305426549462 Down 0.320400211332717 Rfabg Retinoid- and fatty acid-binding glycoprotein, isoform D K03900|1|1e-08|64.7|gga:419031|von Willebrand factor - - - 5740597 420.00 0.615 0.605 -0.0236512680646453 Down 0.0413749834896315 RYamide RYamide - - - - 33351 1853.04 867.94 867.175 -0.0012721482758117 Down 0.0473187161537445 Eno enolase, isoform F K01689|1|0.0|821|dse:Dsec_GM16597|enolase [EC:4.2.1.11] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 38547 1001.00 3.015 1.185 -1.34727094300183 Down 0.468465196143178 CG12607 CG12607, isoform D - - - - 34169 2818.69 7.385 7.66 0.052746471160168 Up 0.0950667018887862 CG13398 CG13398, isoform B K12461|1|3e-11|71.2|dre:436931|fibroblast growth factor receptor substrate 2 - GO:0005102//receptor binding - 32534 1456.18 14.44 13.155 -0.134459493721282 Down 0.231277242108044 PGRP-LE peptidoglycan recognition protein LE, isoform B K01446|1|0.0|662|dme:Dmel_CG8995|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding GO:0023060;GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0010259//multicellular organismal aging;GO:0002376//immune system process;GO:0031349//positive regulation of defense response 39027 2222.18 111.62 100.235 -0.15520919556643 Down 0.357449478272355 pix pixie, isoform B K06174|1|0.0|1226|dsi:Dsim_GD12951|ATP-binding cassette, sub-family E, member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0043021//ribonucleoprotein complex binding;GO:0051540;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0043021//ribonucleoprotein complex binding;GO:0051540;GO:0032559 GO:0006412//translation;GO:0016070//RNA metabolic process;GO:0040007//growth;GO:0043066//negative regulation of apoptotic process;GO:0006412//translation;GO:0016070//RNA metabolic process;GO:0040007//growth;GO:0043066//negative regulation of apoptotic process 34743 1191.00 25.185 17.735 -0.505965400722998 Down 0.570862501651037 CG9377 CG9377 K01312|1|6e-24|111|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09626|2|8e-19|94.7|rno:302971|protease, serine, 22 [EC:3.4.21.-];K01324|3|1e-18|94.0|gga:422723|plasma kallikrein [EC:3.4.21.34];K09641|4|1e-17|90.5|ecb:100067298|transmembrane protease, serine 11D [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 326112 1708.00 0.115 0.465 2.01559685505102 Up 0.22833839651301 PH4alphaSG1 prolyl-4-hydroxylase-alpha SG1 K00472|1|0.0|1111|dme:Dmel_CG31014|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019798 GO:0008152//metabolic process;GO:0007431//salivary gland development 8674088 1028.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 CG42634 CG42634 - - - - 43220 596.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG6403 CG6403, isoform B - - GO:0030247//polysaccharide binding GO:0006022 42162 5619.39 7.905 6.405 -0.303566892016724 Down 0.326905296526218 sr stripe, isoform E K09203|1|2e-121|437|cqu:CpipJ_CPIJ010041|early growth response protein 1;K12497|5|4e-58|227|dre:436920|early growth response protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0005488//binding GO:0009888//tissue development;GO:0007267//cell-cell signaling;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development;GO:0007424//open tracheal system development;GO:0061061//muscle structure development 41797 2739.57 5.405 4.965 -0.122500900206276 Down 0.144894994056267 CG3631 CG3631, isoform E - - - - 38810 1430.00 12.835 12.385 -0.0514894273290551 Down 0.112567692510897 CG43780 CG43780, isoform B - - - - 38826 2121.00 0.875 0.28 -1.64385618977472 Down 0.292794875181614 CG8563 CG8563, isoform B K08637|1|1e-44|181|hsa:51200|carboxypeptidase A4 [EC:3.4.17.-];K08779|5|3e-43|176|tgu:100224866|carboxypeptidase A1 [EC:3.4.17.1] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 32833 1817.00 5.36 6.525 0.283744900999475 Up 0.288469158631621 CG15046 CG15046 - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 317963 1205.00 0.51 0.535 0.0690416444296514 Up 0.049432043323207 CG32298 CG32298 - - - - 10178961 640.00 145.25 103.335 -0.491209179764248 Down 0.632710342094836 CG42808 CG42808 - - - - 32419 2143.23 614.04 407.06 -0.593091178049904 Down 0.674910844010038 CG9512 CG9512, isoform B K00108|1|1e-121|437|dme:Dmel_CG9509|choline dehydrogenase [EC:1.1.99.1];K00115|5|3e-99|362|dme:Dmel_CG12398|glucose dehydrogenase (acceptor) [EC:1.1.99.10] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0009888//tissue development;GO:0044281//small molecule metabolic process 32122 2795.00 35.46 28.975 -0.291383875004855 Down 0.468168009509972 FucT6 alpha1,6-fucosyltransferase K00717|1|0.0|1263|dme:Dmel_CG2448|glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68] GO:0031228//intrinsic to Golgi membrane GO:0046921//alpha-(1->6)-fucosyltransferase activity GO:0006486//protein glycosylation;GO:0007166//cell surface receptor signaling pathway 35959 6552.84 9.505 9.82 0.0470363976661413 Up 0.0997556465460309 CG13954 CG13954, isoform D - - - - 37189 1589.00 0.12 0.11 -0.125530882083859 Down 0.0444459120327566 CG18605 CG18605 K10631|1|4e-23|109|dvi:Dvir_GJ19922|E3 ubiquitin-protein ligase Topors [EC:6.3.2.19] - GO:0005488//binding - 42056 1102.00 17.055 16.615 -0.0377084619213723 Down 0.104543653414344 CG5220 CG5220 K02427|1|3e-171|600|dme:Dmel_CG5220|ribosomal RNA large subunit methyltransferase E [EC:2.1.1.-] - - - 19835203 681.00 0.185 0.42 1.18286405714981 Up 0.168768986923788 14462659 1166.00 2.39 1.83 -0.385166969696706 Down 0.219191652357681 42663 1128.00 18.75 14.31 -0.389866923543938 Down 0.488376700567957 Dph5 diphthamide methyltransferase K00586|1|7e-153|540|dme:Dmel_CG31289|diphthine synthase [EC:2.1.1.98] - GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0017182 319027 2426.00 1.205 1.975 0.712819506834504 Up 0.285827499669793 CG31921 CG31921 - - - - 246605 655.00 103.265 95.235 -0.116787575163612 Down 0.289657905164443 CG30423 CG30423 - - - - 33184 2929.42 9.32 8.405 -0.149082135418113 Down 0.214998018755779 Tbc1d15-17 TBC1 domain family, member 15/17 ortholog, isoform C K13136|1|3e-120|433|nvi:100114269|gem associated protein 8;K11452|2|1e-19|99.0|tgu:100222038|chromobox protein 4 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 43792 2365.49 223.005 226.085 0.0197892199637396 Up 0.0921938977677982 CaMKI Calcium/calmodulin-dependent protein kinase I, isoform I K08794|1|0.0|635|dme:Dmel_CG1495|calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] - - - 35898 1498.21 43.505 43.23 -0.00914838221418523 Down 0.0631686699247127 CG8229 CG8229, isoform E - - - - 34803 3891.10 30.255 34.19 0.176400838099277 Up 0.347378153480386 cenG1A centaurin gamma 1A, isoform C K12491|1|0.0|1409|dme:Dmel_CG31811|Arf-GAP, GTPase, ANK repeat and PH domain-containing protein 1/2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0032561//guanyl ribonucleotide binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0032561//guanyl ribonucleotide binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0032561//guanyl ribonucleotide binding GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction 35420 2931.39 41.395 33.845 -0.290513801798236 Down 0.476720380398891 Cul-2 cullin 2, isoform B K03870|1|0.0|1501|dme:Dmel_CG1512|cullin 2 GO:0000151//ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 41903 450.00 1.2 1.245 0.0531113364595622 Up 0.051182142385418 CG12784 CG12784 - - - - 10178914 1167.46 3.61 3.635 0.00995652703242311 Up 0.0432901862369568 CG42876 CG42876, isoform B - - - - 36215 937.00 1.45 0.79 -0.876128341837831 Down 0.276317527407212 kappaTry kappaTry K01312|1|4e-51|201|dpo:Dpse_GA11598|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 318951 856.00 0.46 1.375 1.57972585235501 Up 0.358109893012812 CG31804 CG31804 - - - - 41217 9870.92 29.14 29.965 0.0402774965059175 Up 0.119006736230353 Glut4EF Glut4EF, isoform H - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 33921 2321.36 14.61 11.795 -0.308780759564036 Down 0.409622242768459 Ent2 equilibrative nucleoside transporter 2, isoform B K03323|1|1e-85|317|cel:ZK809.4|equilibrative nucleoside transporter, ENT family GO:0044464//cell part GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0051234//establishment of localization 37192 777.00 0.16 0.01 -4 Down 0.178939373926826 CG15115 CG15115 - - - - 42469 681.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG15696 CG15696 K09341|1|4e-12|70.5|bfo:BRAFLDRAFT_278777|homeobox protein MSX GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 34019 1321.00 0.26 0.23 -0.176877762084079 Down 0.0562343151499141 CG15818 CG15818 K05328|1|2e-11|70.5|dan:Dana_GF15877|transient receptor potential cation channel subfamily C, invertebrate;K06560|2|4e-08|59.3|nve:NEMVE_v1g238062|mannose receptor, C type;K10066|5|9e-08|58.2|dre:492459|collectin sub-family member 11 - - - 31197 1348.94 0.355 0.36 0.0201778819376303 Up 0.0413749834896315 CG14053 CG14053, isoform B - - - - 19834742 698.00 0.23 0.01 -4.52356195605701 Down 0.229362039360719 42490 2619.48 33.56 31.61 -0.0863616805353248 Down 0.208922203143574 Mvl malvolio, isoform H K12347|1|0.0|1092|dse:Dsec_GM15109|natural resistance-associated macrophage protein GO:0016021//integral to membrane;GO:0044424//intracellular part;GO:0016021//integral to membrane;GO:0044424//intracellular part;GO:0016021//integral to membrane;GO:0044424//intracellular part;GO:0016021//integral to membrane;GO:0044424//intracellular part GO:0015082;GO:0015291//secondary active transmembrane transporter activity;GO:0015082;GO:0015291//secondary active transmembrane transporter activity;GO:0015082;GO:0015291//secondary active transmembrane transporter activity;GO:0015082;GO:0015291//secondary active transmembrane transporter activity GO:0055066;GO:0055065//metal ion homeostasis;GO:0050909//sensory perception of taste;GO:0035434//copper ion transmembrane transport;GO:0055066;GO:0055065//metal ion homeostasis;GO:0050909//sensory perception of taste;GO:0035434//copper ion transmembrane transport;GO:0055066;GO:0055065//metal ion homeostasis;GO:0050909//sensory perception of taste;GO:0035434//copper ion transmembrane transport;GO:0055066;GO:0055065//metal ion homeostasis;GO:0050909//sensory perception of taste;GO:0035434//copper ion transmembrane transport 35172 1440.00 18.955 22.5 0.247346544933755 Up 0.395819574692907 Ttc19 tetratricopeptide repeat domain 19 K10407|1|2e-06|53.9|cbr:CBG09366|kinesin light chain - GO:0003824//catalytic activity - 19834991 380.00 10.01 7.665 -0.385084277177216 Down 0.412528067626469 34012 4053.92 1024.71 1381.19 0.430696119192865 Up 0.620723814555541 ninaC neither inactivation nor afterpotential C, isoform D K08834|1|0.0|2142|dme:Dmel_CG5125|myosin III [EC:2.7.11.1] GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0016028//rhabdomere;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0016028//rhabdomere GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0016887//ATPase activity GO:0050658//RNA transport;GO:0015031//protein transport;GO:0009586;GO:0006996//organelle organization;GO:0006464//cellular protein modification process;GO:0050658//RNA transport;GO:0015031//protein transport;GO:0009586;GO:0006996//organelle organization;GO:0006464//cellular protein modification process 32509 1171.95 4.175 5.36 0.360456803096358 Up 0.309998679170519 CG15601 CG15601, isoform D - - - - 35561 1663.00 30.75 30.785 0.00164115810112319 Up 0.0434552899220711 Fmo-2 Flavin-containing monooxygenase 2 K00485|1|0.0|895|dme:Dmel_CG3174|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0042598;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0030554//adenyl nucleotide binding GO:0008152//metabolic process 32645 2575.00 12.73 9.27 -0.457591175275827 Down 0.481541408004227 Axs abnormal X segregation K13982|1|1e-46|188|dgr:Dgri_GH10918|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13] GO:0031965//nuclear membrane;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton - GO:0007051//spindle organization;GO:0007143//female meiosis;GO:0045132//meiotic chromosome segregation 44149 2823.84 386.05 430.53 0.157326057372161 Up 0.370624752344472 Acon aconitase, isoform F K01681|1|0.0|1521|dse:Dsec_GM23397|aconitate hydratase 1 [EC:4.2.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0051536//iron-sulfur cluster binding;GO:0016836//hydro-lyase activity;GO:0051536//iron-sulfur cluster binding;GO:0016836//hydro-lyase activity;GO:0051536//iron-sulfur cluster binding;GO:0016836//hydro-lyase activity GO:0009060//aerobic respiration;GO:0009060//aerobic respiration;GO:0009060//aerobic respiration 19836207 602.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 326155 3963.54 12.21 13.98 0.195301160388033 Up 0.303031303658698 CG31739 CG31739, isoform C K01876|1|0.0|2024|dme:Dmel_CG31739|aspartyl-tRNA synthetase [EC:6.1.1.12] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 3354977 860.42 46.675 50.795 0.122036470014043 Up 0.276218465196143 MED21 mediator complex subunit 21, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 43610 664.00 7.65 9.66 0.336563441255759 Up 0.378912957337208 CG15536 CG15536 - - - - 37237 584.92 122.915 115.68 -0.0875215291397356 Down 0.235437854972923 Elongin-C elongin C, isoform B K03872|1|2e-63|241|dya:Dyak_GE13845|transcription elongation factor B, polypeptide 1 - - - 41861 4628.00 20.39 19.655 -0.0529654115925024 Down 0.128087438911637 Sra-1 specifically Rac1-associated protein 1 K05749|1|0.0|2605|dya:Dyak_GE24298|cytoplasmic FMR1 interacting protein - - - 31263 2235.00 0.14 0.19 0.440572591385981 Up 0.0738343679830934 fs(1)Ya female sterile (1) young arrest - - - - 41895 3950.00 0.135 0.055 -1.29545588352617 Down 0.0990291903315282 CG18519 CG18519 K00106|1|2e-139|497|dre:560486|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2];K00157|3|2e-138|493|ecb:100070976|aldehyde oxidase [EC:1.2.3.1] - - - 3772408 168.00 0.35 0.01 -5.12928301694497 Down 0.297120591731607 318737 2796.00 0.11 0.115 0.0641303374197159 Up 0.0422335226522256 Muc96D mucin 96D - - GO:0030247//polysaccharide binding GO:0006022 34395 3195.51 23.165 21.17 -0.129925413025682 Down 0.259542992999604 GATAd GATAd, isoform C K09183|1|3e-14|80.9|api:100164123|GATA-binding protein 4/5/6 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent 14462765 1860.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 37808 1450.00 1.04 1.38 0.408084738637077 Up 0.170023774930656 fzr2 fizzy-related 2 K03364|1|0.0|907|dme:Dmel_CG16783|cell division cycle 20-like protein 1, cofactor of APC complex GO:0005813//centrosome GO:0016787//hydrolase activity GO:0016477//cell migration;GO:0048592//eye morphogenesis;GO:0030154//cell differentiation;GO:0009057//macromolecule catabolic process;GO:0007096//regulation of exit from mitosis;GO:0007560//imaginal disc morphogenesis 35698 6378.56 62.53 86.23 0.463641362755617 Up 0.61121384229296 CG43340 CG43340, isoform Q K09880|1|1e-13|80.9|aag:AaeL_AAEL000109|enolase-phosphatase E1 [EC:3.1.3.77];K11974|2|3e-12|75.9|dan:Dana_GF14481|RING finger protein 31;K10429|3|2e-11|73.2|dse:Dsec_GM19138|microtubule-associated protein 1;K00944|4|8e-10|67.8|cfa:480491|nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior 40257 1370.36 6.71 6.62 -0.0194815493929658 Down 0.0573900409457139 CG5274 CG5274, isoform B - - - - 43401 4100.07 5.12 5.775 0.17367713630342 Up 0.193138290846652 CG1647 CG1647, isoform B K09228|1|2e-11|72.4|ptr:739406|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 45064 2444.00 6.45 5.59 -0.206450877467426 Down 0.230517765156518 Nsun2 NOP2-Sun domain family, member 2 ortholog K00599|1|6e-13|76.6|dre:553534| [EC:2.1.1.-] - GO:0003676//nucleic acid binding;GO:0016741 - 19836237 888.00 0.275 0.575 1.06413033741972 Up 0.190067362303527 12798225 2032.00 0.385 0.615 0.675727964644338 Up 0.147503632281073 39759 3600.16 42.535 41.48 -0.0362345599476168 Down 0.123860784572712 ClC-c chloride channel-c, isoform D K05331|1|0.0|1592|dse:Dsec_GM25583|chloride channel, invertebrate GO:0031224//intrinsic to membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0031224//intrinsic to membrane GO:0005254//chloride channel activity;GO:0005254//chloride channel activity GO:0006754//ATP biosynthetic process;GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport 42452 3682.00 6.845 8.16 0.253518610713596 Up 0.292035398230089 Oct-TyrR Octopamine-Tyramine receptor, isoform B K04139|1|1e-42|175|ecb:100051684|adrenergic receptor alpha-2B;K04165|5|2e-41|171|tca:658532|Octopamine receptor GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0008227//G-protein coupled amine receptor activity;GO:0008227//G-protein coupled amine receptor activity GO:0007606//sensory perception of chemical stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007606//sensory perception of chemical stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 50205 888.38 141.885 31.33 -2.17910540175459 Down 0.791308942015586 CG16926 CG16926, isoform B - - - - 5740704 274.00 4.145 10.89 1.39355994722116 Up 0.653975696737551 CG34212 CG34212, isoform B - - - - 39546 749.00 0.12 0.12 0 - 0.0382380134724607 CG9040 CG9040 - - - - 43451 4472.00 2.6 3.05 0.230297619421794 Up 0.170618148197068 CG11898 CG11898 K10835|1|0.0|2521|dme:Dmel_CG11898|xenobiotic-transporting ATPase [EC:3.6.3.44];K05673|2|0.0|944|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|3|0.0|869|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 31343 1997.00 0.155 0.14 -0.146841388329271 Down 0.045238409721305 CG15239 CG15239 - - - - 43900 1230.00 15.65 21.74 0.474189283207329 Up 0.544644036454894 Crg-1 circadianly regulated gene - GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006355//regulation of transcription, DNA-dependent 37988 649.17 23.885 28.165 0.237798594768283 Up 0.40268788799366 CG2811 CG2811, isoform C - - - - 31029 1427.00 0.08 0.075 -0.093109404391481 Down 0.0382380134724607 CG13358 CG13358 - - - - 35114 1643.00 0.64 0.365 -0.810175441119983 Down 0.172071060626073 CG15161 CG15161 - - - GO:0010927 36531 1312.00 0.24 0.215 -0.158697746019058 Down 0.0504556861709153 CG6347 CG6347 K01371|1|1e-76|286|dme:Dmel_CG4847|cathepsin K [EC:3.4.22.38];K01365|3|5e-65|248|dmo:Dmoj_GI21205|cathepsin L [EC:3.4.22.15] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42457 891.00 0.54 1.685 1.64171727901839 Up 0.397206445647867 Pros28.1A proteasome alpha4 subunit, Testis-specific 1 K02731|1|5e-138|490|dme:Dmel_CG17268|20S proteasome subunit alpha 4 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 37398 2860.60 4.73 5.355 0.179046391410861 Up 0.190265486725664 CG34396 CG34396, isoform D K05323|1|6e-29|130|cel:C52B9.6|potassium channel subfamily K, invertebrate;K04923|2|8e-17|89.7|bta:539593|potassium channel subfamily K member 15 - - - 40762 1135.00 0.04 0.51 3.6724253419715 Up 0.299597147008321 Osi8 osiris 8 K01759|1|3e-14|79.0|aag:AaeL_AAEL002957|lactoylglutathione lyase [EC:4.4.1.5] - - - 33922 1973.94 7.63 9.055 0.247031584115637 Up 0.299762250693435 CG13766 CG13766, isoform B - - - - 32859 1596.00 0.835 0.915 0.13199554580999 Up 0.0716219786025624 Cyp308a1 Cyp308a1 K07424|1|4e-48|192|ame:410490|cytochrome P450, family 3, subfamily A [EC:1.14.14.1];K00517|2|4e-44|179|dme:Dmel_CG1895| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0006805//xenobiotic metabolic process 33739 2359.36 111.415 138.15 0.310292083791999 Up 0.532492405230485 qtc quick-to-court, isoform N K10352|1|1e-05|52.4|dre:561431|myosin heavy chain;K12478|2|1e-05|52.4|tgu:100226301|early endosome antigen 1 - - GO:0007617//mating behavior;GO:0007617//mating behavior;GO:0007617//mating behavior;GO:0007617//mating behavior;GO:0007617//mating behavior;GO:0007617//mating behavior;GO:0007617//mating behavior;GO:0007617//mating behavior 40673 1114.00 15.36 18.005 0.229219383469124 Up 0.359067494386475 CG2931 CG2931 K13201|1|1e-09|64.3|tgu:100218641|nucleolysin TIAR GO:0005681//spliceosomal complex GO:0005488//binding GO:0000377 32866 2055.00 9.73 10.515 0.111937139950668 Up 0.180458327829877 CG18259 CG18259 K12881|1|2e-06|54.3|dgr:Dgri_GH18594|THO complex subunit 4 - GO:0005488//binding - 14462873 449.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 35810 765.00 8.315 9.625 0.211070277182357 Up 0.276779817725532 CG18449 CG18449 - - - - 19834919 801.00 0.21 0.12 -0.807354922057604 Down 0.0982366926429798 34402 1138.24 44.42 44.98 0.0180742682308361 Up 0.0839717342491084 CG5045 CG5045, isoform B K01358|1|4e-142|504|dme:Dmel_CG5045|ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 44128 3444.54 6.24 6.355 0.0263460961427106 Up 0.0651829348831066 lmgB lemming B, isoform D K03358|1|3e-132|303|dan:Dana_GF14365|anaphase-promoting complex subunit 11 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007067//mitosis;GO:0007067//mitosis 39417 2055.33 31.42 29.33 -0.0993061095372405 Down 0.225333509443931 Gap69C ADP-ribosylation factor GTPase activating protein 1, isoform B K12492|1|0.0|791|dme:Dmel_CG4237|ADP-ribosylation factor GTPase-activating protein 1 - GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0032561//guanyl ribonucleotide binding GO:0032012//regulation of ARF protein signal transduction 39945 1960.00 2.63 3.265 0.312020192254128 Up 0.223187161537446 CG12229 CG12229 K00873|1|0.0|1075|dme:Dmel_CG12229|pyruvate kinase [EC:2.7.1.40] - GO:0031420;GO:0016301//kinase activity GO:0006007//glucose catabolic process 41298 8592.00 0.595 0.49 -0.280107919192735 Down 0.088033284902919 CG14692 CG14692 K10429|1|1e-25|120|phu:Phum_PHUM399550|microtubule-associated protein 1;K11657|4|1e-16|90.5|tca:657224|remodeling and spacing factor 1 - GO:0019887//protein kinase regulator activity GO:0023060 5740774 537.00 0.085 0.595 2.8073549220576 Up 0.295040285299168 CG34214 CG34214 - - - - 12798085 6542.00 0.63 0.56 -0.169925001442312 Down 0.0715889578655396 36079 2426.46 15.1 14.425 -0.0659772306795965 Down 0.143409060890239 CG12913 CG12913, isoform B K00746|1|0.0|956|dme:Dmel_CG12913|N-acetylgalactosaminyltransferase I [EC:2.4.1.174] GO:0000139//Golgi membrane GO:0016757//transferase activity, transferring glycosyl groups GO:0006024//glycosaminoglycan biosynthetic process 37299 1259.00 4.365 1.295 -1.75302955594289 Down 0.57158895786554 Cpr56F cuticular protein 56F - - - - 32386 907.00 0.13 0.195 0.584962500721156 Up 0.0797781006472064 betaNACtes2 betaNACtes2 K01527|1|5e-09|61.6|dsi:Dsim_GD10924|nascent polypeptide-associated complex subunit beta - - - 10178862 451.00 0.37 0.21 -0.81713594285019 Down 0.128582749966979 CG42714 CG42714 - - - - 50433 361.00 2.025 0.675 -1.58496250072116 Down 0.424910844010038 Peritrophin-15a Peritrophin-15a - GO:0044421//extracellular region part GO:0030247//polysaccharide binding GO:0006022 2768680 5067.04 13.88 12.62 -0.137295657595712 Down 0.236461497820631 Myo95E myosin 95E, isoform J K10356|1|0.0|1163|aga:AgaP_AGAP004403|myosin I GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 37431 1131.00 1.365 1.47 0.106915203916512 Up 0.0734050984017963 CG9752 CG9752 - - - - 39198 5652.43 40.64 48.735 0.262057842278474 Up 0.454233258486329 A2bp1 Ataxin-2 binding protein 1, isoform M K13091|1|4e-09|64.7|ame:552289|RNA-binding protein 39 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 40148 1466.00 1036.225 1154.11 0.155443440390353 Up 0.374257033416986 Gbeta76C G protein beta-subunit 76C K07972|1|0.0|732|dya:Dyak_GE19620|guanine nucleotide binding protein (G protein), beta, other GO:0042995//cell projection;GO:0019897//extrinsic to plasma membrane;GO:0044424//intracellular part GO:0017111//nucleoside-triphosphatase activity GO:0009586;GO:0010863//positive regulation of phospholipase C activity;GO:0007186//G-protein coupled receptor signaling pathway 19835264 566.00 0.01 0.165 4.04439411935845 Up 0.184883106590939 32852 989.00 46.855 42.965 -0.125041114270398 Down 0.29008717474574 CG6617 CG6617 - - - - 50424 1670.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 Muc26B mucin 26B - - GO:0030247//polysaccharide binding GO:0006022 42334 1698.00 0.07 0.13 0.893084796083488 Up 0.0826178840311716 CG7333 CG7333 K08202|1|1e-51|204|aag:AaeL_AAEL012443|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 19835430 884.00 0.09 0.265 1.55799545312089 Up 0.150112270505878 3354991 2592.12 4.79 5.325 0.15275586937702 Up 0.170089816404702 CG17167 CG17167, isoform F K13752|1|5e-59|229|ssc:100156914|solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 42125 1134.00 24.775 18.54 -0.41824381344832 Down 0.529982829216748 CG7523 CG7523 - - - - 318637 416.00 0.61 1.155 0.921011703853171 Up 0.254424778761062 CG31230 CG31230 - - - - 40665 4170.00 22.195 27.65 0.317044771796976 Up 0.477545898824462 Nmdar1 NMDA receptor 1 K05208|1|0.0|1922|dme:Dmel_CG2902|glutamate receptor, ionotropic, N-methyl D-aspartate 1 GO:0030313;GO:0008328//ionotropic glutamate receptor complex;GO:0044430//cytoskeletal part GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0007613//memory;GO:0007267//cell-cell signaling;GO:0007215//glutamate receptor signaling pathway;GO:0055065//metal ion homeostasis;GO:0006873//cellular ion homeostasis;GO:0008306//associative learning 246585 1695.00 0.075 0.265 1.82102985895468 Up 0.158928807290979 CG30385 CG30385 - - - - 37859 7151.33 9.905 10.945 0.14404307429146 Up 0.219951129309206 enok enoki mushroom, isoform B K11306|1|0.0|3263|dme:Dmel_CG11290|histone acetyltransferase MYST4 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016746//transferase activity, transferring acyl groups GO:0010468//regulation of gene expression;GO:0034728//nucleosome organization 40063 1802.00 25.18 23.97 -0.0710483740698836 Down 0.167316074494783 CSN1b COP9 complex homolog subunit 1 b K12175|1|0.0|842|dse:Dsec_GM14913|COP9 signalosome complex subunit 1 GO:0044424//intracellular part;GO:0043234//protein complex - GO:0031647//regulation of protein stability 40495 5134.14 103.15 106.015 0.0395245840791293 Up 0.134064192312772 SPoCk secretory pathway calcium atpase, isoform G K01537|1|0.0|1619|dme:Dmel_CG32451|Ca2+-transporting ATPase [EC:3.6.3.8];K10830|1|0.0|1619|dme:Dmel_CG32451|manganese-transporting ATPase [EC:3.6.3.35] GO:0031224//intrinsic to membrane;GO:0042579//microbody;GO:0031224//intrinsic to membrane;GO:0042579//microbody;GO:0031224//intrinsic to membrane;GO:0042579//microbody;GO:0031224//intrinsic to membrane;GO:0042579//microbody;GO:0031224//intrinsic to membrane;GO:0042579//microbody GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0019932//second-messenger-mediated signaling;GO:0009206;GO:0006874//cellular calcium ion homeostasis;GO:0070838//divalent metal ion transport;GO:0019932//second-messenger-mediated signaling;GO:0009206;GO:0006874//cellular calcium ion homeostasis;GO:0070838//divalent metal ion transport;GO:0019932//second-messenger-mediated signaling;GO:0009206;GO:0006874//cellular calcium ion homeostasis;GO:0070838//divalent metal ion transport;GO:0019932//second-messenger-mediated signaling;GO:0009206;GO:0006874//cellular calcium ion homeostasis;GO:0070838//divalent metal ion transport;GO:0019932//second-messenger-mediated signaling;GO:0009206;GO:0006874//cellular calcium ion homeostasis;GO:0070838//divalent metal ion transport 40761 2690.00 0.14 0.105 -0.415037499278844 Down 0.0678576145819575 Osi7 osiris 7 - - - - 42115 1988.09 11.105 10.225 -0.11910854971787 Down 0.193369436005812 sll slalom, isoform B - - - - 38724 494.00 0.61 0.01 -5.93073733756289 Down 0.398659358076872 CG13299 CG13299 - - - - 43063 1435.00 2.51 2.385 -0.0736980979452604 Down 0.0725795799762251 CG10559 CG10559 - - - - 40759 889.00 0.18 0.155 -0.215728691055437 Down 0.0521727644961036 Osi5 osiris 5, isoform B - - - - 42240 2190.00 5.265 4.75 -0.148506017807407 Down 0.167183991546691 Cpsf73 cleavage and polyadenylation specificity factor 73 K13148|1|5e-96|352|cin:100186018|integrator complex subunit 11 [EC:3.1.27.-] GO:0005849//mRNA cleavage factor complex GO:0003824//catalytic activity GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing 31861 756.00 1.37 1.485 0.116287037840239 Up 0.0779949808479725 CG15368 CG15368 K12163|1|6e-15|79.7|xla:379323|AN1-type zinc finger and ubiquitin domain-containing protein 1 - GO:0046914//transition metal ion binding - 33950 7802.26 15.215 12.52 -0.281259771581978 Down 0.390106987187954 CG11321 CG11321, isoform K K11974|1|3e-72|271|dme:Dmel_CG11321|RING finger protein 31 GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - 35311 1941.00 24.14 22.21 -0.120216283208041 Down 0.246070532294281 Arpc2 Actin-related protein 2/3 complex, subunit 2, isoform B K05758|1|5e-163|574|dsi:Dsim_GD24255|actin related protein 2/3 complex, subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0034062//RNA polymerase activity GO:0030030//cell projection organization;GO:0030041//actin filament polymerization;GO:0008064//regulation of actin polymerization or depolymerization 14462722 2095.00 7.83 9.52 0.281949266016903 Up 0.334698190463611 42350 5442.67 55.965 63.63 0.185182260713775 Up 0.386408664641395 GluClalpha GluClalpha, isoform P K05273|1|0.0|860|dya:Dyak_GE25622|glutamate receptor, anionic, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 39531 550.17 5.07 6.605 0.381572814243487 Up 0.351241579712059 CG13737 CG13737, isoform B - - - - 3346202 526.00 89.35 100.52 0.169942941951803 Up 0.371483291507066 IFa SIFamide - - - - 39826 3387.13 134.295 111.995 -0.261971267294357 Down 0.483720776647735 fax failed axon connections, isoform F - - - GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048667//cell morphogenesis involved in neuron differentiation 3771963 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 38942 1569.00 2.17 1.8 -0.269698136114805 Down 0.160645885616167 DNApol-alpha50 DNA polymerase alpha 50kD K02684|1|0.0|900|dme:Dmel_CG7108|DNA primase small subunit [EC:2.7.7.-] GO:0043234//protein complex GO:0003899//DNA-directed RNA polymerase activity;GO:0034061 GO:0006259//DNA metabolic process 39017 2245.61 74.135 66.33 -0.160493290678406 Down 0.348897107383437 Tsp66E tetraspanin 66E, isoform C K06509|1|9e-140|497|dpo:Dpse_GA18582|kangai 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 2768718 5054.16 113.795 174.87 0.61984563853035 Up 0.672566371681416 qvr quiver, isoform C - GO:0009986//cell surface;GO:0005887//integral to plasma membrane GO:0035091//phosphatidylinositol binding GO:0042753//positive regulation of circadian rhythm;GO:0007271//synaptic transmission, cholinergic;GO:0042749//regulation of circadian sleep/wake cycle 19835113 896.47 22.54 15.495 -0.540684760586005 Down 0.574527803460573 36751 874.00 0.36 0.155 -1.21572869105544 Down 0.15430590410778 CG8299 CG8299 K01312|1|9e-33|140|mdo:100010951|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 318909 580.00 39.045 43.515 0.156374983793885 Up 0.331528199709417 CG31715 CG31715, isoform B K10380|1|5e-12|70.5|cel:B0350.2|ankyrin - - - 35594 2336.65 29.73 29.49 -0.0116936408459074 Down 0.0621120063399815 koi klaroid, isoform F K11498|1|6e-06|53.5|dmo:Dmoj_GI20661|centromeric protein E;K09291|2|8e-06|53.1|aag:AaeL_AAEL003882|nucleoprotein TPR - - - 40044 1221.00 45.755 37.505 -0.286846464246055 Down 0.481046096948884 Aut1 Autophagy-specific gene 3 K08343|1|1e-158|559|dme:Dmel_CG6877|autophagy-related protein 3 GO:0044424//intracellular part - GO:0044248//cellular catabolic process;GO:0006810//transport 32963 2290.95 10.59 11.815 0.15791703998151 Up 0.245806366398098 MKP-4 MAPK phosphatase 4, isoform C K01090|1|0.0|728|dme:Dmel_CG14211|protein phosphatase [EC:3.1.3.16];K01104|1|0.0|728|dme:Dmel_CG14211|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity GO:0043407//negative regulation of MAP kinase activity;GO:0006464//cellular protein modification process 34070 1118.75 624.72 616.17 -0.0198812752258767 Down 0.0936137894597807 Rack1 receptor of activated protein kinase C 1, isoform D K00567|1|3e-148|524|xla:446289|methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63];K01062|2|1e-30|134|bfo:BRAFLDRAFT_59218|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0004871//signal transducer activity GO:0033057;GO:0000377;GO:0007292//female gamete generation;GO:0007444//imaginal disc development 42449 3544.33 50.03 54.245 0.116696711813726 Up 0.276845859199577 Nep4 neprilysin 4, isoform C K08635|1|3e-163|576|tca:660501|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 38596 1849.00 18.59 18.33 -0.020319984379596 Down 0.0738343679830934 CG10671 CG10671, isoform B - GO:0031090//organelle membrane;GO:0031090//organelle membrane - GO:0010876//lipid localization;GO:0010876//lipid localization 250735 3429.03 27.5 24.11 -0.189799967696858 Down 0.3486989829613 fdl fused lobes, isoform F K12373|1|0.0|1341|dme:Dmel_CG8824|beta-hexosaminidase [EC:3.2.1.52] GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane GO:0004563//beta-N-acetylhexosaminidase activity;GO:0043167//ion binding;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0043167//ion binding GO:0007417//central nervous system development;GO:0006026;GO:0006487//protein N-linked glycosylation;GO:0007417//central nervous system development;GO:0006026;GO:0006487//protein N-linked glycosylation 246523 1001.71 1.35 1.765 0.38670877622035 Up 0.18848236692643 CG30278 CG30278, isoform C - - - - 36020 4285.56 132.125 123.64 -0.0957579122991844 Down 0.256075815612204 CG1516 CG1516, isoform M K01958|1|0.0|2206|dme:Dmel_CG1516|pyruvate carboxylase [EC:6.4.1.1] GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559;GO:0019842//vitamin binding;GO:0016885;GO:0032559 GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process 3885616 2029.03 0.595 0.505 -0.236606280556149 Down 0.0815612204464404 CG17140 CG17140, isoform B K05862|1|2e-24|114|dvi:Dvir_GJ17632|voltage-dependent anion channel GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0005244//voltage-gated ion channel activity;GO:0005244//voltage-gated ion channel activity GO:0006811//ion transport;GO:0006811//ion transport 12798102 249.00 271.165 1107.185 2.02965341972059 Up 0.794710077928939 32423 2045.00 0.04 0.025 -0.678071905112638 Down 0.0550785893541144 Eo ecdysone oxidase K00108|1|0.0|1182|dme:Dmel_CG9504|choline dehydrogenase [EC:1.1.99.1];K10724|2|0.0|702|dpo:Dpse_GA21839|ecdysone oxidase [EC:1.1.3.16] - GO:0030554//adenyl nucleotide binding;GO:0016899//oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor GO:0001703//gastrulation with mouth forming first;GO:0016125//sterol metabolic process;GO:0048513//organ development 37679 5760.00 11.355 12.405 0.127594029185543 Up 0.214700832122573 CG34371 CG34371, isoform B K06763|1|1e-15|87.0|dre:327429|contactin 5;K06255|2|2e-11|73.2|bta:444872|heparan sulfate proteoglycan 2 (perlecan);K06491|4|5e-11|71.6|gga:427968|neural cell adhesion molecule;K06756|5|2e-10|69.3|dre:556537|neuronal cell adhesion molecule GO:0044464//cell part - - 31787 1116.00 0.04 0.045 0.169925001442312 Up 0.0382380134724607 Cp36 chorion protein 36 - - GO:0005198//structural molecule activity GO:0003006//developmental process involved in reproduction 42295 4134.00 28.075 30.95 0.140653386813663 Up 0.290945713908334 Ppcs phosphopantothenoylcysteine synthetase, isoform C K01922|1|2e-80|300|bfo:BRAFLDRAFT_282135|phosphopantothenate-cysteine ligase [EC:6.3.2.5] - - GO:0016477//cell migration;GO:0007293//germarium-derived egg chamber formation;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0007010//cytoskeleton organization;GO:0055088//lipid homeostasis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0000904//cell morphogenesis involved in differentiation;GO:0016477//cell migration;GO:0007293//germarium-derived egg chamber formation;GO:0007472//wing disc morphogenesis;GO:0007423//sensory organ development;GO:0007010//cytoskeleton organization;GO:0055088//lipid homeostasis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0000904//cell morphogenesis involved in differentiation 5740222 141.00 0.445 0.01 -5.4757334309664 Down 0.335292563730022 14462698 647.00 0.125 0.235 0.910732661902913 Up 0.108440100383041 32898 3412.45 23.03 25.01 0.118990646388124 Up 0.247457403249241 RhoGAP18B Rho GTPase activating protein at 18B, isoform H K10360|1|1e-15|84.7|cel:F56A6.2|myosin IX GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0030534//adult behavior;GO:0023060;GO:0030036//actin cytoskeleton organization;GO:0030534//adult behavior;GO:0023060;GO:0030036//actin cytoskeleton organization;GO:0030534//adult behavior;GO:0023060;GO:0030036//actin cytoskeleton organization;GO:0030534//adult behavior;GO:0023060;GO:0030036//actin cytoskeleton organization 33308 1830.01 35.09 24.865 -0.496943516599405 Down 0.589915466913221 CG5001 CG5001, isoform D K09511|1|0.0|684|dme:Dmel_CG5001|DnaJ homolog subfamily B member 5 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process 40987 1481.00 31.98 31.285 -0.0316988347809938 Down 0.102199181085722 eIF4AIII eIF4AIII K13025|1|0.0|786|dme:Dmel_CG7483|translation initiation factor eIF-4A 3 [EC:3.6.1.-] GO:0043234//protein complex;GO:0005681//spliceosomal complex GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0006412//translation;GO:0000377;GO:0033554//cellular response to stress 36715 1800.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 Ir52a ionotropic receptor 52a - - - - 40246 3062.00 4.565 1.315 -1.79555206069192 Down 0.581032888654075 in inturned - GO:0016020//membrane GO:0005488//binding GO:0001736//establishment of planar polarity;GO:0009987//cellular process 39752 1512.00 49.575 42.715 -0.214869990067567 Down 0.403183199049003 CG5895 CG5895, isoform C - - GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 40146 3120.32 2.865 3.53 0.301133044514275 Up 0.224739136177519 tey teyrha-meyrha, isoform D - - - - 35574 1139.79 10.615 11.96 0.172113018292728 Up 0.260698718795404 CG9422 CG9422, isoform D - - GO:0005488//binding;GO:0005488//binding - 19836201 713.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 31928 1263.44 39.31 27.385 -0.521510483395557 Down 0.603189803196407 CG1889 CG1889, isoform E K06252|1|3e-35|149|gga:396213|tenascin;K10104|4|8e-35|147|cin:100180273|ficolin - GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0023060;GO:0023060;GO:0023060 33467 990.00 18.765 16.865 -0.154011971868849 Down 0.274468366133932 aph-1 anterior pharynx defective 1, isoform B K06172|1|2e-115|415|dme:Dmel_CG2855|anterior pharynx defective 1 GO:0016021//integral to membrane GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0044093 37845 2123.00 4.25 4.055 -0.0677609268077911 Down 0.0883304715361247 CG13563 CG13563 - - - - 31311 5934.00 1.245 1.075 -0.211809082478621 Down 0.102694492141065 CG12535 CG12535, isoform F - - - - 42044 837.54 51.46 35.24 -0.546237532813387 Down 0.626172236164311 CG18622 CG18622, isoform C - - - - 37721 849.00 2.395 4.585 0.936896077858874 Up 0.473055078589354 CG3906 CG3906 - - - - 42296 1344.00 20.825 23.505 0.174651184940826 Up 0.316734909523181 CG5835 CG5835 - - - - 34457 1717.00 0.375 0.515 0.457681836687337 Up 0.110883634922731 CG7329 CG7329, isoform B K01046|1|0.0|919|dme:Dmel_CG7329|triacylglycerol lipase [EC:3.1.1.3];K01066|3|6e-84|311|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - - GO:0044238//primary metabolic process 43447 1036.01 459.345 462.71 0.0105301535485926 Up 0.0705983357548541 Pglym78 phosphoglyceromutase, isoform C K01834|1|7e-139|493|dme:Dmel_CG1721|phosphoglycerate mutase [EC:5.4.2.1] - GO:0004619//phosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 35583 3336.00 34.34 37.44 0.12469039558127 Up 0.267798177255316 phtf phtf - - - - 32758 1289.00 0.185 0.22 0.249978253008348 Up 0.0625742966583014 OdsH Ods-site homeobox K09328|1|8e-57|221|tca:657741|homeobox protein Unc-4 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 32295 1156.93 38.13 35.63 -0.0978340475928157 Down 0.232135781270638 Yippee yippee, isoform B - - GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0043169//cation binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0043169//cation binding GO:0008152//metabolic process;GO:0008152//metabolic process 41074 1531.50 24.8 25.195 0.0227973356955154 Up 0.0805045568617092 CG11975 CG11975, isoform B - - - - 33779 836.00 0.39 0.67 0.780686971595524 Up 0.171146479989433 tomb tombola - GO:0044427//chromosomal part GO:0003676//nucleic acid binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048870//cell motility;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0006277//DNA amplification 3885645 1206.00 1.225 0.795 -0.623754983718215 Down 0.204959714700832 CG34057 CG34057, isoform B K00731|1|2e-71|269|dya:Dyak_GE10709|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part;GO:0044464//cell part GO:0008378//galactosyltransferase activity;GO:0008378//galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 32480 2349.00 1.27 0.99 -0.359328066692556 Down 0.150508519350152 CG9203 CG9203 - - GO:0003676//nucleic acid binding;GO:0016829//lyase activity GO:0006259//DNA metabolic process;GO:0009124//nucleoside monophosphate biosynthetic process 32561 6880.99 40.79 50.445 0.306495772455216 Up 0.503797384757628 mmd mind-meld, isoform J K06835|1|4e-105|383|xtr:677729|disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 40897 3299.70 28.905 30.11 0.0589236357078001 Up 0.155560692114648 alpha-Est9 alpha-Esterase-9, isoform D K01066|1|0.0|651|dpo:Dpse_GA10843|esterase / lipase [EC:3.1.1.-];K01044|3|3e-165|582|dme:Dmel_CG1131|carboxylesterase [EC:3.1.1.1];K01050|3|3e-165|582|dme:Dmel_CG1131|cholinesterase [EC:3.1.1.8] - GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity - 41826 4368.45 3.915 4.935 0.334037777165357 Up 0.28371417250033 CG6752 CG6752, isoform B K12169|1|0.0|2608|dme:Dmel_CG6752|Kip1 ubiquitination-promoting complex protein 1 [EC:6.3.2.19] - - - 41868 2665.00 15.26 14.285 -0.0952539258981585 Down 0.185807687227579 CG6194 Autophagy-specific gene 4b K08342|1|0.0|1292|dme:Dmel_CG6194|autophagy-related protein 4 [EC:3.4.22.-] - - - 42285 1304.00 8.38 6.91 -0.278264533311093 Down 0.316833971734249 Prp18 Prp18 K12817|1|0.0|682|dme:Dmel_CG6011|pre-mRNA-splicing factor 18 GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus GO:0008187//poly-pyrimidine tract binding GO:0000377 3771877 1064.38 7295.765 5978.21 -0.287345684090078 Down 0.529454497424383 Adh alcohol dehydrogenase, isoform I K00001|1|2e-144|511|dme:Dmel_CG3481|alcohol dehydrogenase [EC:1.1.1.1] GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process;GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process;GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process;GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process;GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process 34037 2714.10 19.21 9.16 -1.06843801556858 Down 0.667910447761194 CG6739 CG6739, isoform B K04550|1|2e-18|95.1|aga:AgaP_AGAP012372|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) - - - 43644 1349.00 0.625 0.885 0.50182126542091 Up 0.15153216219786 Pka-C2 cAMP-dependent protein kinase 2, isoform C K04345|1|0.0|730|dme:Dmel_CG12066|protein kinase A [EC:2.7.11.11] - GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 19835717 557.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 42880 3064.93 27.805 29.28 0.0745712164793453 Up 0.173061682736759 twin twin, isoform F K12603|1|0.0|1100|dme:Dmel_CG31137|CCR4-NOT transcription complex subunit 6 [EC:3.1.-.-] GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0005488//binding;GO:0016787//hydrolase activity;GO:0005488//binding;GO:0016787//hydrolase activity;GO:0005488//binding;GO:0016787//hydrolase activity;GO:0005488//binding;GO:0005488//binding;GO:0016787//hydrolase activity;GO:0005488//binding;GO:0016787//hydrolase activity GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007292//female gamete generation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007292//female gamete generation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007292//female gamete generation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007292//female gamete generation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007292//female gamete generation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007292//female gamete generation 44531 15695.16 15.035 20.17 0.423886216038959 Up 0.51320829480914 rg rugose, isoform R K07295|1|3e-22|109|dpe:Dper_GL19043|nuclear receptor subfamily 2 group A;K12602|2|3e-06|56.6|api:100164117|WD repeat-containing protein 61;K11127|3|8e-06|55.1|tad:TRIADDRAFT_52303|telomerase protein component 1 GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0033036;GO:0001745//compound eye morphogenesis;GO:0033036;GO:0001745//compound eye morphogenesis;GO:0033036;GO:0001745//compound eye morphogenesis;GO:0033036;GO:0001745//compound eye morphogenesis;GO:0033036;GO:0001745//compound eye morphogenesis 3771952 653.00 1.005 0.645 -0.639824435755674 Down 0.187987055871087 CG33665 CG33665 - - - - 38630 6602.00 4.95 5.315 0.102641166564133 Up 0.126469422797517 l(3)psg2 lethal (3) persistent salivary gland 2 K13172|1|3e-26|122|dvi:Dvir_GJ12538|serine/arginine repetitive matrix protein 2 - - - 32675 5230.49 10.375 6.63 -0.646030561009062 Down 0.523940034341567 CG13003 CG13003, isoform C - - - - 43287 919.00 0.09 0.485 2.42998784074482 Up 0.248877294941223 CG14260 CG14260, isoform B K10481|1|1e-06|53.9|nve:NEMVE_v1g209460|BTB/POZ domain-containing protein 9 - GO:0005488//binding - 59232 549.00 1.11 0.58 -0.936434871222534 Down 0.250429269581297 CG16741 CG16741 - - - - 39332 2996.34 25.005 28.225 0.17475697595279 Up 0.327367586844538 Klp68D Kinesin-like protein at 68D, isoform B K10394|1|0.0|1365|dme:Dmel_CG7293|kinesin family member 3/17 GO:0005871//kinesin complex GO:0003774//motor activity;GO:0032559 GO:0008088//axon cargo transport 32953 746.93 694.455 671.365 -0.0487838844589031 Down 0.162098798045172 RpS10b ribosomal protein S10b, isoform E K02947|1|6e-61|233|dme:Dmel_CG14206|small subunit ribosomal protein S10e GO:0015630//microtubule cytoskeleton;GO:0015935//small ribosomal subunit;GO:0015630//microtubule cytoskeleton;GO:0015935//small ribosomal subunit - - 14462904 751.00 1.055 0.705 -0.581547836308391 Down 0.182670717210408 19835662 1248.78 0.16 0.16 0 - 0.0382380134724607 19835948 465.00 0.01 0.205 4.35755200461808 Up 0.213941355171047 319016 3572.00 14.465 1.685 -3.10174582674774 Down 0.76390173028662 CG31904 CG31904, isoform D K05038|1|5e-19|96.3|gga:422974|solute carrier family 6 (neurotransmitter transporter, glycine) member 5;K05042|2|2e-18|94.4|spu:577731|solute carrier family 6 (neurotransmitter transporter, glycine) member 9 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport;GO:0006810//transport 37141 2350.63 8.335 8.695 0.0610038283201704 Up 0.10959582617884 Atg7 Autophagy-specific gene 7, isoform B K08337|1|0.0|857|dme:Dmel_CG5489|autophagy-related protein 7 - - - 14462736 715.00 0.525 0.545 0.0539388071108035 Up 0.0451063267732136 37205 5205.76 63.285 61.875 -0.0325069681988107 Down 0.109331660282658 cora coracle, isoform G K06107|1|0.0|802|dme:Dmel_CG11949|erythrocyte membrane protein band 4.1 - - - 14462498 939.00 0.045 0.095 1.07800251200127 Up 0.0796790384361379 41823 2534.85 156.25 118.78 -0.395564252035625 Down 0.593118478404438 CG6904 glycogen synthase, isoform D K00693|1|0.0|1312|dya:Dyak_GE26410|glycogen(starch) synthase [EC:2.4.1.11] - - - 32463 1616.00 14.915 16.235 0.122343406950876 Up 0.223550389644697 CG12608 CG12608 K03364|1|7e-06|52.4|api:100168994|cell division cycle 20-like protein 1, cofactor of APC complex;K12602|2|9e-06|52.0|tca:664186|WD repeat-containing protein 61 - - - 32153 5103.71 10.125 10.725 0.0830557397275583 Up 0.144597807423062 Upf1 Upf1, isoform B K10706|1|4e-49|197|gga:417170|senataxin [EC:3.6.1.-];K13983|3|1e-45|186|hmg:100201712|putative helicase MOV10L1 [EC:3.6.4.13] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0035194//posttranscriptional gene silencing by RNA;GO:0000956//nuclear-transcribed mRNA catabolic process 39206 2149.33 20.08 15.92 -0.334918933407123 Down 0.459549597147008 CG32066 CG32066, isoform C - - - - 34966 1822.70 40.15 40.445 0.0105613732298982 Up 0.0639611676132611 Syx5 syntaxin 5, isoform B K08490|1|0.0|769|dme:Dmel_CG4214|syntaxin 5 GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0006909//phagocytosis;GO:0051301//cell division;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0006909//phagocytosis;GO:0051301//cell division;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport 42281 989.00 4.905 6.855 0.482903529559987 Up 0.403810593052437 CG14285 CG14285 K10260|1|3e-06|52.4|cin:100178491|F-box and WD-40 domain protein 7 - - - 19835291 616.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 33047 899.58 20.94 20.8 -0.00967791390235378 Down 0.0576542068418967 GstT3 glutathione S transferase T3, isoform C K00799|1|2e-154|544|dme:Dmel_CG1702|glutathione S-transferase [EC:2.5.1.18] - - - 260645 1435.00 87.25 106.485 0.287423183220598 Up 0.509113723418307 nimB2 nimrod B2 K01691|1|1e-26|120|dgr:Dgri_GH24528|WNT inhibitory factor 1 - - - 12797889 281.00 0.805 0.91 0.176877762084079 Up 0.0812640338132347 CG43450 CG43450 - - - - 31733 2555.00 1.605 0.89 -0.850696056155905 Down 0.286586976621318 cyr cypher, isoform D - - - - 37834 1065.00 96.435 92.34 -0.0626011190694935 Down 0.175472196539427 Adk2 adenylate kinase-2 K00939|1|4e-134|477|dme:Dmel_CG3140|adenylate kinase [EC:2.7.4.3] GO:0005740//mitochondrial envelope GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0032559 GO:0009180 41654 2415.00 0.02 0.035 0.807354922057604 Up 0.0552767137762515 Ir87a ionotropic receptor 87a - - - - 47272 908.00 30.535 34.815 0.189245178222387 Up 0.3621384229296 cbx crossbronx, isoform C K10573|1|5e-06|52.0|dre:797853|ubiquitin-conjugating enzyme E2 A [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0003006//developmental process involved in reproduction;GO:0060255;GO:0006464//cellular protein modification process;GO:0003006//developmental process involved in reproduction 39786 677.00 60.33 6.645 -3.18253447775033 Down 0.817758552370889 CG13065 CG13065 - - - - 39150 670.00 118.995 178.52 0.585184756881391 Up 0.6658961828028 Ilp2 Insulin-like peptide 2 - - GO:0005102//receptor binding GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0060249//anatomical structure homeostasis;GO:0035264//multicellular organism growth;GO:0010259//multicellular organismal aging;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030537//larval behavior;GO:0055088//lipid homeostasis 42484 2517.91 35.48 40.835 0.202800218065236 Up 0.383172632413155 Rlip Ral interacting protein, isoform B K08773|1|6e-61|236|bta:523324|RalA-binding protein 1 GO:0044464//cell part GO:0005488//binding GO:0006897//endocytosis;GO:0023060 318037 1835.00 1.07 1.07 -3.20342650381492e-16 Down 0.0382380134724607 CG32454 CG32454 K01262|1|3e-30|133|der:Dere_GG18008|X-Pro aminopeptidase [EC:3.4.11.9] - GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity - 10178864 983.00 5.49 5.98 0.123339335192906 Up 0.15222559767534 CG42711 CG42711 - - - - 38484 3065.95 308.37 399.59 0.373858060756969 Up 0.586910579844142 Gad1 glutamic acid decarboxylase 1, isoform D K01580|1|0.0|1064|dsi:Dsim_GD13295|glutamate decarboxylase [EC:4.1.1.15] - GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0048741//skeletal muscle fiber development;GO:0043112//receptor metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0007626//locomotory behavior;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009605//response to external stimulus;GO:0048741//skeletal muscle fiber development;GO:0043112//receptor metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0007626//locomotory behavior;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009605//response to external stimulus;GO:0048741//skeletal muscle fiber development;GO:0043112//receptor metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0007626//locomotory behavior;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009605//response to external stimulus 39571 2847.01 0.15 0.155 0.0473057147783565 Up 0.0382380134724607 nan nanchung, isoform B K04974|1|7e-58|226|rno:116469|transient receptor potential cation channel subfamily V member 5;K04975|4|3e-55|217|rno:114246|transient receptor potential cation channel subfamily V member 6 GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0009415//response to water stimulus;GO:0006810//transport;GO:0050954//sensory perception of mechanical stimulus;GO:0050906//detection of stimulus involved in sensory perception 41316 2090.62 10.76 10.435 -0.0442474773967896 Down 0.0959582617884031 Tpc1 thiamine pyrophosphate carrier protein 1, isoform B K03454|1|3e-17|90.5|bfo:BRAFLDRAFT_277098|mitochondrial carrier protein, MC family;K05863|3|8e-16|85.9|cin:100177254|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator);K13354|4|1e-15|85.1|tad:TRIADDRAFT_21077|solute carrier family 25 member 17 GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport 10178944 825.00 4.025 4.285 0.0903064211105207 Up 0.103751155725796 49816 2185.54 25.605 28.535 0.156307003927556 Up 0.311814819706776 CycK cyclin K, isoform C - - - - 39177 2112.00 0.09 0.125 0.473931188332412 Up 0.0617157574957073 CG14160 CG14160 - GO:0031224//intrinsic to membrane - GO:0006810//transport 36723 1755.00 11.57 4.94 -1.22780591752281 Down 0.642616563201691 CG8192 CG8192 - - GO:0030247//polysaccharide binding GO:0006022 45881 727.00 11.945 8.785 -0.443292662447956 Down 0.465394267600053 ix intersex - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity;GO:0005515//protein binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0018993//somatic sex determination 246441 2791.00 0.105 0.015 -2.8073549220576 Down 0.120030379078061 CG30080 CG30080, isoform C - - GO:0004175//endopeptidase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0019538//protein metabolic process;GO:0006351//transcription, DNA-dependent 41250 1060.00 10.365 11.84 0.191948964519535 Up 0.280048870690794 CG12817 CG12817 - - GO:0046872//metal ion binding - 42621 2693.00 1.435 2.145 0.579926910823858 Up 0.264892352397306 CG7069 CG7069 K00873|1|0.0|1111|dse:Dsec_GM26421|pyruvate kinase [EC:2.7.1.40] GO:0044444//cytoplasmic part GO:0031420;GO:0016301//kinase activity GO:0006007//glucose catabolic process 35955 5689.51 13.575 16.635 0.293269668191142 Up 0.408532558446705 Drep-2 DNA fragmentation factor-related protein 2, isoform D K02310|1|1e-08|63.5|nve:NEMVE_v1g129698|DNA fragmentation factor, 45 kD, alpha subunit GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0005488//binding GO:0012501//programmed cell death;GO:0012501//programmed cell death 36385 1535.00 1.28 1.685 0.396604781181859 Up 0.184651961431779 CG17760 CG17760 K04634|1|0.0|677|dme:Dmel_CG17760|guanine nucleotide binding protein (G protein), alpha q polypeptide GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus 38102 3429.57 24.515 30.115 0.296817497297307 Up 0.466715097080967 CG12502 CG12502, isoform D - - - - 41048 1271.00 9.22 10 0.117161344232749 Up 0.18547747985735 CG13318 CG13318 K01312|1|1e-35|150|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09640|2|1e-35|150|xtr:448231|transmembrane protease, serine 9 [EC:3.4.21.-];K09639|4|9e-35|147|mdo:100018588|transmembrane protease, serine 8 [EC:3.4.21.-];K01324|5|3e-34|146|hsa:3818|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 3354883 546.00 0.08 0.185 1.20945336562895 Up 0.108142913749835 CG40249 CG40249 - - - - 32976 4875.00 9.835 9.96 0.0182206897895509 Up 0.0611544049663188 dome domeless K01104|1|0.0|1477|dpe:Dper_GL18308|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044459//plasma membrane part GO:0004872//receptor activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0001709//cell fate determination;GO:0007243//intracellular protein kinase cascade;GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0048729//tissue morphogenesis;GO:0060541//respiratory system development;GO:0002376//immune system process 44259 2593.00 6.975 7.37 0.07947140237852 Up 0.123464535728437 nbs nbs, isoform F K10867|1|0.0|1609|dme:Dmel_CG6754|nijmegen breakage syndrome protein 1 GO:0043229//intracellular organelle - GO:0044237//cellular metabolic process;GO:0050794//regulation of cellular process 39481 1497.00 0.335 0.575 0.779400860486603 Up 0.156584334962356 CG11253 ZMYND10 homolog - - GO:0046914//transition metal ion binding - 42203 3041.24 37.665 41.02 0.123102962487196 Up 0.270208691057984 PKD protein kinase D, isoform I K06070|1|0.0|1524|dme:Dmel_CG7125|protein kinase D [EC:2.7.11.13] GO:0044444//cytoplasmic part;GO:0016021//integral to membrane GO:0043169//cation binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0023033;GO:0023060 3346209 4665.35 8.08 8.975 0.151556645958619 Up 0.213578127063796 Ddr discoidin domain receptor, isoform G K05125|1|1e-50|201|xtr:779954|discoidin domain receptor family member 2 [EC:2.7.10.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0023060 3885567 3641.44 56.21 55.185 -0.0265506378807879 Down 0.106656980583807 Dyrk3 Dual-specificity tyrosine phosphorylation-regulated kinase 3, isoform E K08825|1|0.0|1508|dme:Dmel_CG40478|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase [EC:2.7.12.1] - - - 41041 1159.00 2.815 2.745 -0.0363287730750309 Down 0.0579183727380795 ranshi ranshi K09228|1|4e-32|139|mmu:630579|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 46017 5036.05 32.565 24.21 -0.427719147337364 Down 0.555309734513274 l(2)01289 lethal (2) 01289, isoform M K13984|1|2e-12|75.9|hmg:100208732|thioredoxin domain-containing protein 5;K09583|4|4e-10|68.2|ecb:100070524|protein disulfide isomerase family A, member 5 [EC:5.3.4.1] - GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis 5740483 840.00 0.145 0.365 1.33184356375244 Up 0.165169726588297 CG34308 CG34308 K03155|1|1e-62|140|dya:Dyak_GE26249|timeless - GO:0046872//metal ion binding - 318946 1643.00 1.02 1.75 0.778785769860833 Up 0.28463875313697 CG31798 CG31798, isoform B - - - - 14462523 372.00 3.21 3.845 0.260410300839523 Up 0.210705322942808 CG43935 CG43935 - - - - 326202 2987.00 0.05 0.2 2 Up 0.141658961828028 CG32228 CG32228 K09566|1|1e-10|68.9|ecb:100052595|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8] - - - 37730 2472.97 11.97 11.19 -0.0972131159671076 Down 0.173358869369964 pita pita, isoform B K09228|1|8e-47|189|api:100159445|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0006261//DNA-dependent DNA replication;GO:0006261//DNA-dependent DNA replication 50079 366.10 926.825 540.8 -0.777201808087148 Down 0.712950733060362 CG6503 CG6503, isoform C - - - - 31221 3252.83 14.685 14.555 -0.0128284262020855 Down 0.0570268128384626 phl pole hole, isoform E K02644|1|0.0|1379|dme:Dmel_CG2845|pole hole - - - 19835774 2748.00 9.715 9.685 -0.00446194698209091 Down 0.0427618544445912 37516 3394.00 10.665 8.85 -0.269134605370211 Down 0.338099326376965 GlcT-1 ceramide glucosyltransferase K00720|1|0.0|860|dme:Dmel_CG6437|ceramide glucosyltransferase [EC:2.4.1.80] GO:0012505//endomembrane system;GO:0031090//organelle membrane GO:0035251//UDP-glucosyltransferase activity GO:0006915//apoptotic process 42016 2200.00 3.68 2.385 -0.625716500051501 Down 0.357383436798309 CG14892 CG14892 K01324|1|2e-19|97.8|mmu:16621|plasma kallikrein [EC:3.4.21.34];K09640|5|1e-18|95.1|dre:562051|transmembrane protease, serine 9 [EC:3.4.21.-] - - - 14462878 1240.00 3.795 5.425 0.515523251916375 Up 0.381422533350944 CG44006 CG44006 - - - - 32951 2308.00 0.055 0.025 -1.13750352374993 Down 0.0654471007792894 CG14219 CG14219 K00680|1|9e-159|560|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 49241 4131.00 9.76 10.55 0.112289946031661 Up 0.180458327829877 rec recombination-defective, isoform B K10737|1|2e-99|364|aga:AgaP_AGAP002580|minichromosome maintenance protein 8 - GO:0003676//nucleic acid binding;GO:0032559 GO:0006259//DNA metabolic process 19836027 423.00 0.4 0.34 -0.234465253637023 Down 0.0703011491216484 38091 2049.00 93.25 107.135 0.200254241554633 Up 0.413188482366926 emc extra macrochaetae K04680|1|5e-81|302|dme:Dmel_CG1007|inhibitor of DNA binding, dominant negative helix-loop-helix protein GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001752//compound eye photoreceptor fate commitment;GO:0051100//negative regulation of binding;GO:0002118//aggressive behavior;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007281//germ cell development;GO:0048565//digestive tract development;GO:0007476//imaginal disc-derived wing morphogenesis 12798255 245.00 0.01 0.22 4.4594316186373 Up 0.222989037115308 CG43166 CG43166 - - - - 33236 1232.00 6.205 6.6 0.0890348141154592 Up 0.126403381323471 Ipk2 Ipk2 K00328|1|3e-31|135|dre:790916|inositol-polyphosphate multikinase [EC:2.7.1.151] - GO:0051766//inositol trisphosphate kinase activity - 34455 1872.46 5.51 8.975 0.703859620139256 Up 0.51958129705455 w-cup world cup, isoform B K04573|1|3e-07|57.0|ecb:100054129|neurofilament medium polypeptide (neurofilament 3);K11657|2|2e-06|54.3|tca:657224|remodeling and spacing factor 1;K10429|3|6e-06|52.8|tgu:100220659|microtubule-associated protein 1;K09880|4|8e-06|52.4|nvi:100117336|enolase-phosphatase E1 [EC:3.1.3.77];K12327|5|8e-06|52.4|tgu:100222084|caldesmon - - - 326169 1134.00 6.26 3.91 -0.678994049625266 Down 0.459186369039757 CG31883 CG31883 - - - - 50417 414.95 463.725 499.645 0.107633911285354 Up 0.28510104345529 Neb-cGP Neb-cGP, isoform B - - - - 40774 3762.00 0.13 0.1 -0.37851162325373 Down 0.0612534671773874 Osi17 osiris 17, isoform D K04209|1|8e-20|99.8|tca:656041|neuropeptide Y receptor, invertebrate - - - 37585 1924.00 5.365 5.32 -0.0121519252553323 Down 0.0472856954167217 CG17807 CG17807 K10770|1|0.0|1170|dme:Dmel_CG17807|alkylated DNA repair protein alkB homolog 8 - GO:0016741;GO:0005488//binding - 41597 1249.00 14.18 16.155 0.188123218025848 Up 0.307555144630828 CG7488 CG7488 K03979|1|8e-06|51.6|mcc:700182|GTP-binding protein - - - 19834824 3776.00 2.205 2.185 -0.0131453760569223 Down 0.0432901862369568 - CG45101 - - - - 19835100 1017.00 0.24 0.19 -0.337034987277571 Down 0.072150310394928 38945 4339.96 26.98 26.31 -0.0362790997823783 Down 0.114780081891428 GapcenA GTPase activating protein and centrosome-associated ortholog, isoform B K11837|1|1e-15|85.9|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15] GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 30976 4348.93 17.71 16.385 -0.112188539209155 Down 0.214998018755779 CG13375 CG13375, isoform C K07843|1|2e-32|140|dre:393504|RAS, dexamethasone-induced 1;K07844|4|3e-32|139|xla:444515|RASD family, member 2 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 40732 1330.00 6.565 8.63 0.394565548286068 Up 0.394267600052833 ECSIT ECSIT K04405|1|0.0|840|dme:Dmel_CG10610|evolutionarily conserved signaling intermediate in Toll pathways - - GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response;GO:0023060 43637 1646.21 56.64 66.37 0.228710008809823 Up 0.435774666490556 CG2246 CG2246, isoform P K00948|1|0.0|749|dme:Dmel_CG2246|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] - GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778 GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 5740846 3125.00 0.205 0.215 0.068712750084014 Up 0.042365605600317 CG40625 JYalpha K01539|1|0.0|1280|phu:Phum_PHUM361900|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane GO:0008556//potassium-transporting ATPase activity;GO:0032559 GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis 33289 2701.00 22.46 24.72 0.138320815503773 Up 0.27664773477744 CG4552 CG4552 K04707|1|2e-10|68.6|spu:583481|E3 ubiquitin-protein ligase CBL [EC:6.3.2.19] GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 36484 900.00 14.275 73.78 2.36973904344461 Up 0.79170519085986 AttC Attacin-C - GO:0044421//extracellular region part - GO:0042742//defense response to bacterium 3772676 2228.00 0.18 0.255 0.502500340529183 Up 0.0887597411174217 ste24c ste24c prenyl protease type I, isoform D K06013|1|3e-71|270|dmo:Dmoj_GI21207|STE24 endopeptidase [EC:3.4.24.84] GO:0044464//cell part;GO:0044464//cell part GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 53578 1015.31 263.46 258.24 -0.0288714565699171 Down 0.114945185576542 Jafrac1 thioredoxin peroxidase 1, isoform E K03386|1|3e-110|397|dsi:Dsim_GD17115|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis;GO:0042743//hydrogen peroxide metabolic process;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis 40182 2373.00 0.085 0.06 -0.502500340529183 Down 0.0618808611808216 CG17732 CG17732 - - - - 32047 1435.66 114.605 73.405 -0.64271974646859 Down 0.670717210408136 Rpt3 regulatory particle triple-A ATPase 3, isoform B K03063|1|0.0|784|dme:Dmel_CG16916|26S proteasome regulatory subunit T3 GO:0043073//germ cell nucleus;GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0033554//cellular response to stress;GO:0044267//cellular protein metabolic process 35069 636.00 0.82 1.125 0.456229186598953 Up 0.162660150574561 CG15147 CG15147 - - - - 5740310 4693.57 1.28 0.845 -0.599120563717816 Down 0.20667679302602 Nox NADPH oxidase, isoform E K13411|1|4e-46|187|ssc:397060|dual oxidase [EC:1.6.3.1 1.11.1.-] GO:0031224//intrinsic to membrane GO:0030554//adenyl nucleotide binding;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0008152//metabolic process 38160 2834.89 22.35 23.83 0.0925041201195907 Up 0.197728173292828 Ptp61F protein tyrosine phosphatase 61F, isoform E K05696|1|0.0|949|dme:Dmel_CG9181|protein tyrosine phosphatase, non-receptor type 1 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity GO:0010608//posttranscriptional regulation of gene expression;GO:0007049//cell cycle;GO:0006935//chemotaxis;GO:0010004//gastrulation involving germ band extension;GO:0001933//negative regulation of protein phosphorylation;GO:0007292//female gamete generation;GO:0008104//protein localization;GO:0010608//posttranscriptional regulation of gene expression;GO:0007049//cell cycle;GO:0006935//chemotaxis;GO:0010004//gastrulation involving germ band extension;GO:0001933//negative regulation of protein phosphorylation;GO:0007292//female gamete generation;GO:0008104//protein localization;GO:0010608//posttranscriptional regulation of gene expression;GO:0007049//cell cycle;GO:0006935//chemotaxis;GO:0010004//gastrulation involving germ band extension;GO:0001933//negative regulation of protein phosphorylation;GO:0007292//female gamete generation;GO:0008104//protein localization;GO:0010608//posttranscriptional regulation of gene expression;GO:0007049//cell cycle;GO:0006935//chemotaxis;GO:0010004//gastrulation involving germ band extension;GO:0001933//negative regulation of protein phosphorylation;GO:0007292//female gamete generation;GO:0008104//protein localization 14462916 1354.00 0.06 0.1 0.736965594166206 Up 0.0694426099590543 326185 1775.00 0.025 0.05 1 Up 0.0577202483159424 CG32054 CG32054 K07191|1|2e-08|60.8|bta:282359|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4;K07299|3|5e-08|59.7|xtr:779913|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1;K07593|5|6e-08|59.3|mdo:100010342|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2 GO:0031224//intrinsic to membrane - GO:0006810//transport 19835493 900.00 0.345 0.295 -0.225881407416328 Down 0.0666688680491349 31818 1266.10 5.96 5.715 -0.0605588322476835 Down 0.0939439968300092 Rbm13 RNA-binding motif protein 13, isoform B - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 37300 912.00 0.56 0.575 0.038135128886771 Up 0.0418702945449742 CkIIbeta2 casein kinase II beta2 subunit K03115|1|2e-130|464|dme:Dmel_CG8914|casein kinase 2, beta polypeptide - - - 12797916 504.00 0.335 0.185 -0.856635824828823 Down 0.124719323735306 CG43295 CG43295 - - - - 39075 958.00 392.42 227.425 -0.787007718394164 Down 0.712125214634791 Hsp26 heat shock protein 26, isoform B K09542|1|7e-23|107|dme:Dmel_CG4533|crystallin, alpha B;K09541|4|2e-17|89.7|gga:418546|crystallin, alpha A GO:0015630//microtubule cytoskeleton GO:0005488//binding GO:0006950//response to stress;GO:0010259//multicellular organismal aging 39082 3842.93 6.77 6.87 0.0211542652431036 Up 0.0586448289525822 CG4022 CG4022, isoform C - - - - 33851 3379.00 18.105 18.595 0.0385265711358102 Up 0.107350416061286 CG13995 CG13995 K04209|1|2e-08|62.0|dan:Dana_GF16373|neuropeptide Y receptor, invertebrate;K04204|3|8e-08|60.1|xtr:100127810|neuropeptide Y receptor Y1 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway 38824 3173.73 17.295 18.55 0.101064173135237 Up 0.201657640998547 smid smallminded, isoform I K13525|1|8e-97|355|bmy:Bm1_47170|transitional endoplasmic reticulum ATPase - GO:0016887//ATPase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016887//ATPase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016887//ATPase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides - 34430 1604.00 29.64 28.015 -0.0813459550756435 Down 0.188746532822613 TfIIB transcription factor IIB, isoform B K03124|1|2e-171|602|dwi:Dwil_GK14874|transcription initiation factor TFIIB GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006412//translation;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0051098//regulation of binding 41929 1478.00 0.425 0.51 0.263034405833794 Up 0.0834764231937657 CG14877 CG14877 K12323|1|3e-26|118|tca:100141543|atrial natriuretic peptide receptor A [EC:4.6.1.2];K12325|2|3e-13|75.5|xla:399384|atrial natriuretic peptide clearance receptor - - - 326121 589.00 27.255 33.84 0.312208648164678 Up 0.483192444855369 CG31126 CG31126 K05527|1|5e-70|263|dme:Dmel_CG31126|BolA protein - - - 31248 3894.57 112.115 130.24 0.216193293764363 Up 0.440265486725664 sgg shaggy, isoform R K03083|1|0.0|743|dse:Dsec_GM16104|glycogen synthase kinase 3 beta [EC:2.7.11.26] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0007472//wing disc morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0007292//female gamete generation;GO:0002682//regulation of immune system process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-dependent;GO:0009880//embryonic pattern specification;GO:0008306//associative learning;GO:0006508//proteolysis;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0006606//protein import into nucleus;GO:0043407//negative regulation of MAP kinase activity;GO:0048511//rhythmic process;GO:0046958//nonassociative learning;GO:0003002//regionalization;GO:0019827//stem cell maintenance;GO:0008589//regulation of smoothened signaling pathway;GO:0007472//wing disc morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0007292//female gamete generation;GO:0002682//regulation of immune system process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-dependent;GO:0009880//embryonic pattern specification;GO:0008306//associative learning;GO:0006508//proteolysis;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0006606//protein import into nucleus;GO:0043407//negative regulation of MAP kinase activity;GO:0048511//rhythmic process;GO:0046958//nonassociative learning;GO:0003002//regionalization;GO:0019827//stem cell maintenance;GO:0008589//regulation of smoothened signaling pathway 33156 5304.26 13.035 11.665 -0.160204275551357 Down 0.255778628978999 l(2)gl lethal (2) giant larvae, isoform K K06094|1|0.0|2125|dme:Dmel_CG2671|lethal giant larvae GO:0043296//apical junction complex;GO:0005578//proteinaceous extracellular matrix;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0043296//apical junction complex;GO:0005578//proteinaceous extracellular matrix;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0043296//apical junction complex;GO:0005578//proteinaceous extracellular matrix;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0043296//apical junction complex;GO:0005578//proteinaceous extracellular matrix;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0043296//apical junction complex;GO:0005578//proteinaceous extracellular matrix;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0043296//apical junction complex;GO:0005578//proteinaceous extracellular matrix;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle GO:0017022//myosin binding;GO:0017022//myosin binding;GO:0017022//myosin binding;GO:0017022//myosin binding;GO:0017022//myosin binding;GO:0017022//myosin binding GO:0007010//cytoskeleton organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0016079//synaptic vesicle exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0007010//cytoskeleton organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0016079//synaptic vesicle exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0007010//cytoskeleton organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0016079//synaptic vesicle exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0007010//cytoskeleton organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0016079//synaptic vesicle exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0007010//cytoskeleton organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0016079//synaptic vesicle exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0007010//cytoskeleton organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0016079//synaptic vesicle exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway 31621 3512.00 0.39 0.505 0.372809263889546 Up 0.101241579712059 iav inactive K04975|1|7e-51|202|mdo:100011069|transient receptor potential cation channel subfamily V member 6 - - - 35336 6375.65 18.955 21.88 0.207034281621913 Up 0.354213446044116 Fs(2)Ket female sterile (2) ketel, isoform E - GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope GO:0008565//protein transporter activity GO:0065008;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0030036//actin cytoskeleton organization 42756 1795.00 1.595 2.8 0.811870403180097 Up 0.362666754721965 CG4434 CG4434 K00261|1|0.0|1080|dme:Dmel_CG4434|glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] GO:0031980 GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors GO:0006519;GO:0006103//2-oxoglutarate metabolic process 12798151 541.00 0.085 0.655 2.94596016028711 Up 0.312145027077004 CG43133 CG43133 - - - - 36371 2184.00 3.685 4.275 0.214259800678191 Up 0.19208162726192 s-cup stanley-cup - - - - 326183 1690.03 2.065 0.58 -1.83201697629187 Down 0.446803592656188 CG32037 CG32037, isoform B - - - - 33789 2949.00 0.02 0.135 2.75488750216347 Up 0.133304715361247 GluRIIB glutamate receptor IIB K05313|1|0.0|729|dme:Dmel_CG6992|glutamate receptor, ionotropic, invertebrate;K05201|4|2e-104|380|dre:561540|glutamate receptor, ionotropic, kainate 1;K05202|5|1e-102|374|xla:100294518|glutamate receptor, ionotropic, kainate 2 GO:0031224//intrinsic to membrane;GO:0030313;GO:0044459//plasma membrane part;GO:0045202//synapse;GO:0044430//cytoskeletal part GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0050804//regulation of synaptic transmission 35332 7266.06 7.14 6.03 -0.243766072129015 Down 0.267864218729362 Hr38 hormone receptor-like in 38, isoform D K08558|1|0.0|741|dme:Dmel_CG1864|nuclear receptor subfamily 4 group A member 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0009888//tissue development;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007275//multicellular organismal development;GO:0009888//tissue development;GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007275//multicellular organismal development 39940 3109.00 10.855 11.735 0.112458115908026 Up 0.186666226390173 sec3 Sec3 ortholog - - - - 14462688 529.00 0.565 0.09 -2.65025396097288 Down 0.281997094175142 35157 3355.00 12.23 11.035 -0.148337774247773 Down 0.238739928675208 CG10431 CG10431, isoform B K09228|1|6e-18|93.6|bta:616883|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 32704 1630.00 0.1 0.34 1.76553474636298 Up 0.179731871615374 CG8918 CG8918 K05755|1|1e-25|117|ecb:100058358|actin related protein 2/3 complex, subunit 4;K06047|3|4e-20|99.8|xtr:100135000|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0043412//macromolecule modification 35652 8279.10 14.005 15.52 0.148186574112621 Up 0.257198520670981 Dscam down syndrome cell adhesion molecule 1, isoform Z K06768|1|0.0|2355|dpo:Dpse_GA14672|Down syndrome cell adhesion molecule like 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding;GO:0043498//cell surface binding;GO:0004888//transmembrane signaling receptor activity GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006897//endocytosis 251711 827.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 CG31517 CG31517, isoform B - - - - 30970 1731.00 4.835 2.945 -0.71524825564638 Down 0.429963016774534 CG3038 CG3038, isoform C K09664|1|4e-29|129|dpo:Dpse_GA10945|beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-];K07819|2|2e-21|103|tca:661600|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-];K03877|5|3e-20|100|tgu:100221638|beta-1,3-galactosyltransferase 5 [EC:2.4.1.-] - - - 19835469 679.00 0.79 0.29 -1.44579975304953 Down 0.261722361643112 19835907 3569.00 4.545 3.775 -0.267803649981666 Down 0.23401796328094 - pre-mod(mdg4)-L - - - - 43906 11254.47 11.65 13 0.158181668374174 Up 0.25452384097213 skd skuld, isoform F - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0016055//Wnt receptor signaling pathway;GO:0006352//DNA-dependent transcription, initiation;GO:0007423//sensory organ development;GO:0006355//regulation of transcription, DNA-dependent;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0016055//Wnt receptor signaling pathway;GO:0006352//DNA-dependent transcription, initiation;GO:0007423//sensory organ development;GO:0006355//regulation of transcription, DNA-dependent;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0016055//Wnt receptor signaling pathway;GO:0006352//DNA-dependent transcription, initiation;GO:0007423//sensory organ development;GO:0006355//regulation of transcription, DNA-dependent;GO:0007450//dorsal/ventral pattern formation, imaginal disc 44446 1660.00 6.59 5.665 -0.218202509187536 Down 0.240820235107648 Hdac3 histone deacetylase 3 K11404|1|0.0|913|dme:Dmel_CG2128|histone deacetylase 3 [EC:3.5.1.98] GO:0043231//intracellular membrane-bounded organelle GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0006476//protein deacetylation;GO:0006915//apoptotic process;GO:0016458//gene silencing 32647 964.00 209.2 359.19 0.77986433381928 Up 0.710243032624488 CG9676 CG9676 K01362|1|1e-50|200|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|5e-40|164|dme:Dmel_CG18444|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835072 398.00 3.09 3.09 0 - 0.0382380134724607 - CG44303 - - - - 19835052 237.00 1.06 0.01 -6.7279204545632 Down 0.514099854708757 40860 943.00 5.655 4.26 -0.408673593763982 Down 0.342292959978867 MAGE MAGE K12464|1|3e-11|69.3|mmu:94275|melanoma-associated antigen D1 - - - 19835189 865.00 0.095 0.22 1.21150410519371 Up 0.123068286884163 35905 1798.00 0.085 0.055 -0.628031222613042 Down 0.0622440892880729 CG8172 CG8172, isoform G K01312|1|2e-65|251|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|2|3e-44|180|xla:446603|plasma kallikrein [EC:3.4.21.34];K09626|3|2e-43|177|rno:302971|protease, serine, 22 [EC:3.4.21.-];K01344|4|2e-43|177|ecb:100051306|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 50302 3251.00 6.2 5.175 -0.26070935288755 Down 0.263373398494254 CG32354 CG32354 K06254|1|1e-40|168|spu:586604|agrin - - - 37728 555.74 615.93 646.625 0.0701628874427635 Up 0.204761590278695 levy levy, isoform B K02266|1|1e-60|231|dme:Dmel_CG17280|cytochrome c oxidase subunit VIa [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain;GO:0042598 GO:0015002//heme-copper terminal oxidase activity GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain 34066 1777.51 18.62 16.575 -0.167844202558843 Down 0.295304451195351 r2d2 r2d2, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0031332;GO:0043231//intracellular membrane-bounded organelle;GO:0031332 GO:0003723//RNA binding;GO:0003723//RNA binding GO:0070828//heterochromatin organization;GO:0002252;GO:0016246//RNA interference;GO:0000904//cell morphogenesis involved in differentiation;GO:0070828//heterochromatin organization;GO:0002252;GO:0016246//RNA interference;GO:0000904//cell morphogenesis involved in differentiation 37778 1686.00 20.59 15.95 -0.368387405980023 Down 0.485669000132083 gbb glass bottom boat, isoform B K04663|1|0.0|889|dme:Dmel_CG5562|bone morphogenetic protein 5/6/7/8 GO:0044421//extracellular region part GO:0005126//cytokine receptor binding GO:0007447//imaginal disc pattern formation;GO:0048634;GO:0050804//regulation of synaptic transmission;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0003006//developmental process involved in reproduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 37948 2070.00 12.195 11.11 -0.134430941407092 Down 0.218002905824858 CG4806 CG4806 K12876|1|3e-09|63.9|smm:Smp_002550.1|RNA-binding protein 8A - GO:0005488//binding - 19836094 1962.00 0.95 5.17 2.44416486198399 Up 0.640173028662 43070 4601.00 5.38 6.22 0.209308407573979 Up 0.228635583146216 CG11902 CG11902 K09228|1|0.0|1203|dpo:Dpse_GA11270|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0005488//binding - 38906 3262.56 35.73 16.185 -1.1424785483761 Down 0.707106062607317 CG13676 CG13676, isoform B - - - - 318720 1782.00 0.49 0.45 -0.122856747785533 Down 0.0565645225201427 CG31413 CG31413 K10758|1|0.0|1082|dme:Dmel_CG31413|thiol oxidase [EC:1.8.3.2] - GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor GO:0008152//metabolic process;GO:0019725//cellular homeostasis 42978 1933.00 0.895 1.555 0.796954992866346 Up 0.270637960639281 CG10845 CG10845 K10396|1|7e-21|102|aga:AgaP_AGAP000561|kinesin family member 5 GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 34715 5882.00 5.77 7.01 0.280843125365141 Up 0.296162990357945 CG16972 CG16972 - - - - 34951 5690.89 13.24 15.475 0.225036287294409 Up 0.34186369039757 CG42817 CG42817, isoform B K05316|1|0.0|676|aga:AgaP_AGAP005490|voltage-dependent calcium channel alpha-2/delta, invertebrate GO:0044464//cell part - - 39856 1412.00 31.49 27.2 -0.211287105997708 Down 0.380167745344076 Su(P) suppressor of ref(2)P sterility K05309|1|3e-124|445|dpe:Dper_GL12723|prostaglandin-E synthase [EC:5.3.99.3] - GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis 43333 3250.00 6.33 5.995 -0.0784457460141179 Down 0.114747061154405 CG12877 CG12877 K01175|1|7e-64|246|hsa:254958| [EC:3.1.-.-];K12579|2|1e-14|82.8|mdo:100016855|interferon-stimulated gene 20 kDa protein [EC:3.1.13.1] GO:0044464//cell part GO:0005488//binding;GO:0004518//nuclease activity - 35730 3528.79 27.865 25.895 -0.105780594947257 Down 0.23586712455422 Nop17l Nop17 like, isoform C - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part - - 35375 1579.00 22.9 24.315 0.0864989932543913 Up 0.195879012019548 CG9257 CG9257 - - - - 39956 6440.60 25.885 32.52 0.3292109392141 Up 0.496697926297715 CG7564 CG7564, isoform D K13212|1|2e-82|306|mdo:100017621|RNA-binding protein Luc7-like 2 GO:0005681//spliceosomal complex - GO:0000377 42654 1055.00 2.27 2.67 0.234147444396639 Up 0.161009113723418 CG33093 CG33093 K06892|1|2e-36|153|spu:760899| - GO:0003824//catalytic activity GO:0008152//metabolic process 32924 3781.14 21.37 18.475 -0.210012543626298 Down 0.353255844670453 CG8034 CG8034, isoform B K11810|1|5e-09|63.2|bfo:BRAFLDRAFT_210112|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 12;K08180|2|8e-08|59.3|dre:561627|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 3;K08190|4|4e-07|57.0|cin:100184819|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14 - - GO:0006810//transport;GO:0006810//transport 14462546 1001.00 0.235 0.435 0.888354644171091 Up 0.14608374058909 31866 2954.00 28.305 28.59 0.0144536963094964 Up 0.0636970017170783 CG12121 CG12121 K04574|1|1e-07|59.3|cfa:442940|neurofilament heavy polypeptide;K11294|2|3e-07|57.8|spu:593162|nucleolin;K04573|3|3e-07|57.8|tgu:751981|neurofilament medium polypeptide (neurofilament 3) GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity - 35771 5042.27 42.035 42.95 0.0310670582625878 Up 0.105402192576938 lig lingerer, isoform K - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part - GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating 37468 1310.71 9.275 8.64 -0.102315969344697 Down 0.159820367190596 pirk poor Imd response upon knock-in, isoform B - - - GO:0009608//response to symbiont;GO:0031348//negative regulation of defense response 42926 563.00 31.47 34.32 0.125072374201122 Up 0.279289393739268 CG13623 CG13623, isoform B - - GO:0051540 GO:0031163 40487 2594.37 22.4 22 -0.0259952085329444 Down 0.0926231673490952 ArfGAP3 ADP-ribosylation factor GTPase activating protein 3, isoform H K12493|1|0.0|1009|dme:Dmel_CG6838|ADP-ribosylation factor GTPase-activating protein 2/3 - GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction 41227 770.00 23.43 25.87 0.142923099821605 Up 0.281865011227051 CG11722 CG11722 - - - - 12798444 151.00 0.76 0.495 -0.618570893363976 Down 0.159391097609299 33481 1884.00 0.53 0.49 -0.113210610447991 Down 0.0557059833575485 CG2975 CG2975 K00731|1|1e-78|294|dan:Dana_GF15693|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0016020//membrane GO:0048531//beta-1,3-galactosyltransferase activity GO:0016266//O-glycan processing;GO:0009653//anatomical structure morphogenesis;GO:0006664//glycolipid metabolic process 36612 6427.14 11.565 13.53 0.226396573340347 Up 0.328721437062475 Asx additional sex combs, isoform D K11471|1|0.0|1058|dme:Dmel_CG8787|additional sex combs-like protein GO:0031519//PcG protein complex;GO:0005720//nuclear heterochromatin;GO:0031519//PcG protein complex;GO:0005720//nuclear heterochromatin GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0030234//enzyme regulator activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0030234//enzyme regulator activity GO:0016458//gene silencing;GO:0007423//sensory organ development;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0045165//cell fate commitment;GO:0035521;GO:0016458//gene silencing;GO:0007423//sensory organ development;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0045165//cell fate commitment;GO:0035521 33806 996.04 57.785 47.99 -0.267961229254668 Down 0.471569145423326 obst-E obstructor-E, isoform B K01873|1|3e-10|65.9|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding GO:0006022;GO:0006022 39872 2005.00 29.965 23.06 -0.377885860918659 Down 0.523477744023247 CG9701 CG9701 K01229|1|4e-131|468|tgu:100229941|lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62];K05350|4|3e-130|465|tca:664577|beta-glucosidase [EC:3.2.1.21] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process 2768958 267.00 0.175 0.235 0.425305834732671 Up 0.0781931052701096 CG33272 CG33272 - - - - 34583 3305.00 0.08 0.24 1.58496250072116 Up 0.143343019416193 CG6614 CG6614, isoform C - - - - 42250 953.00 6.87 2.775 -1.30782232758063 Down 0.593184519878484 CG7714 CG7714 - - - - 31925 1438.00 0.03 0.035 0.222392421336448 Up 0.0461960110949676 CG1986 CG1986, isoform B K01059|1|0.0|746|dme:Dmel_CG1986|lipoprotein lipase [EC:3.1.1.34];K01046|3|4e-33|142|api:100163959|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 246562 538.00 2.065 2.79 0.434123340409742 Up 0.255019152027473 CG30356 CG30356 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - 19834773 296.00 0.455 0.01 -5.5077946401987 Down 0.339420155857879 36886 3293.00 5.34 5.53 0.0504397385471531 Up 0.0824858010830802 IntS8 integrator 8 K13145|1|0.0|1970|dme:Dmel_CG5859|integrator complex subunit 8 - - - 37890 2650.20 7.05 7.275 0.0453239905094903 Up 0.0874719323735306 bs blistered, isoform C K04378|1|4e-113|409|dpo:Dpse_GA17433|serum response factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0035153//epithelial cell type specification, open tracheal system;GO:0006351//transcription, DNA-dependent;GO:0060446//branching involved in open tracheal system development;GO:0007610//behavior;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0010468//regulation of gene expression;GO:0035153//epithelial cell type specification, open tracheal system;GO:0006351//transcription, DNA-dependent;GO:0060446//branching involved in open tracheal system development;GO:0007610//behavior;GO:0008587//imaginal disc-derived wing margin morphogenesis 35696 4258.83 1.925 1.9 -0.0188590272513159 Down 0.0440166424514595 scra scraps, isoform C - GO:0045172//germline ring canal;GO:0015629//actin cytoskeleton;GO:0045172//germline ring canal;GO:0015629//actin cytoskeleton;GO:0045172//germline ring canal;GO:0015629//actin cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0043062//extracellular structure organization;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0016044//cellular membrane organization;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0033206//cytokinesis after meiosis;GO:0032185//septin cytoskeleton organization;GO:0031566//actomyosin contractile ring maintenance;GO:0043062//extracellular structure organization;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0016044//cellular membrane organization;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0033206//cytokinesis after meiosis;GO:0032185//septin cytoskeleton organization;GO:0031566//actomyosin contractile ring maintenance;GO:0043062//extracellular structure organization;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0016044//cellular membrane organization;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0033206//cytokinesis after meiosis;GO:0032185//septin cytoskeleton organization;GO:0031566//actomyosin contractile ring maintenance 46243 16174.30 24.925 24.14 -0.0461678285305366 Down 0.130035662395985 poe purity of essence, isoform B K10691|1|0.0|9548|dme:Dmel_CG14472|E3 ubiquitin-protein ligase UBR4 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity GO:0050953//sensory perception of light stimulus;GO:0042065;GO:0007281//germ cell development 39719 431.00 0.685 0.24 -1.51306958223937 Down 0.245806366398098 CG13445 CG13445 - - - - 34387 1566.28 78.97 45.67 -0.790057900647006 Down 0.691817461365738 CG5384 CG5384, isoform B K11843|1|0.0|957|dme:Dmel_CG5384|ubiquitin carboxyl-terminal hydrolase 14 [EC:3.1.2.15] GO:0015630//microtubule cytoskeleton GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process 37272 6396.00 8.085 9.045 0.161872729147579 Up 0.222989037115308 Toll-7 Toll-7 K05401|1|4e-46|188|dme:Dmel_CG5195|toll-like recepto 3;K06838|4|1e-42|176|ecb:100061086|slit 1 - - - 42803 3818.00 13.31 11.39 -0.22474282420378 Down 0.321555937128517 Hmgcr HMG coenzyme A reductase K00021|1|0.0|1632|dme:Dmel_CG10367|3-hydroxy-3-methylglutaryl-CoA reductase [EC:1.1.1.34] GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0048037//cofactor binding GO:0008354//germ cell migration;GO:0006732//coenzyme metabolic process;GO:0006720//isoprenoid metabolic process;GO:0045137//development of primary sexual characteristics;GO:0009790//embryo development 42967 507.00 2.075 0.995 -1.06034290569064 Down 0.361841236296394 CG13640 CG13640 - - - - 31090 3778.96 57.585 64.42 0.161815599814709 Up 0.34546295073306 CG11448 CG11448, isoform C K13883|1|4e-21|104|xtr:100127814|Rab-interacting lysosomal protein - - - 34656 1815.00 8.18 7.55 -0.115624198729307 Down 0.170056795667679 CG6388 CG6388 K00555|1|0.0|1140|dme:Dmel_CG6388|tRNA (guanine-N2-)-methyltransferase [EC:2.1.1.32] - GO:0003676//nucleic acid binding;GO:0008170//N-methyltransferase activity GO:0006399//tRNA metabolic process 33901 2203.13 7.8 8.01 0.0383281186590993 Up 0.0819904900277374 CG16947 CG16947, isoform B K10144|1|1e-91|337|ame:408590|ring finger and CHY zinc finger domain-containing protein 1 - GO:0046914//transition metal ion binding - 37942 994.00 1.28 1.44 0.169925001442312 Up 0.0974441949544314 CG3640 CG3640 - - - GO:0048609//multicellular organismal reproductive process 33075 2140.00 0.535 0.815 0.60726116782993 Up 0.162429005415401 r-cup ryder cup - - - GO:0007126//meiosis 40327 5138.16 39.715 43.58 0.133982193156085 Up 0.289789988112535 siz schizo, isoform D K12495|1|0.0|1574|dme:Dmel_CG32434|IQ motif and SEC7 domain-containing protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity GO:0002118//aggressive behavior;GO:0000768//syncytium formation by plasma membrane fusion;GO:0032011//ARF protein signal transduction;GO:0002118//aggressive behavior;GO:0000768//syncytium formation by plasma membrane fusion;GO:0032011//ARF protein signal transduction;GO:0002118//aggressive behavior;GO:0000768//syncytium formation by plasma membrane fusion;GO:0032011//ARF protein signal transduction;GO:0002118//aggressive behavior;GO:0000768//syncytium formation by plasma membrane fusion;GO:0032011//ARF protein signal transduction 35234 1317.00 6.91 7.16 0.0512738768759979 Up 0.0905758816536785 CG10189 CG10189, isoform B - GO:0044444//cytoplasmic part GO:0003723//RNA binding GO:0002097 33519 1288.00 6.855 7.75 0.177039644382374 Up 0.224078721437062 CG17260 CG17260, isoform C - - GO:0046914//transition metal ion binding - 37920 602.00 386.075 209.485 -0.882034192019163 Down 0.722922995641263 CG11413 CG11413 - - - - 31184 1870.41 150.925 82.435 -0.872502893513603 Down 0.713446044115705 CG3835 CG3835, isoform C K00100|1|5e-136|484|mcc:702028| [EC:1.1.1.-];K00102|3|3e-38|160|nve:NEMVE_v1g173328|D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] - - - 12798350 415.00 1.835 2.32 0.338344742284359 Up 0.197530048870691 CG43277 CG43277 - - - - 19836120 237.00 1.025 1.215 0.245332404100335 Up 0.111841236296394 12798570 471.54 0.895 1.375 0.619472031147765 Up 0.218333113195087 CG43185 CG43185, isoform D - - - - 32554 1903.00 39.36 42.34 0.10529104866835 Up 0.252806762646942 Lcch3 Ligand-gated chloride channel homolog 3 K05270|1|0.0|914|dsi:Dsim_GD24824|gamma-aminobutyric acid (GABA) receptor, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0015276//ligand-gated ion channel activity;GO:0016917//GABA receptor activity GO:0006810//transport 34127 5321.44 16.42 14.655 -0.164061159088263 Down 0.277043983621714 Pvr PDGF- and VEGF-receptor related, isoform O K05096|1|0.0|2806|dme:Dmel_CG8222|FMS-like tyrosine kinase 1 [EC:2.7.10.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis;GO:0007417//central nervous system development;GO:0065008;GO:0007052//mitotic spindle organization;GO:0006959//humoral immune response;GO:0048534;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0007431//salivary gland development;GO:0002682//regulation of immune system process;GO:0048598//embryonic morphogenesis 41695 688.00 0.12 0.07 -0.777607578663552 Down 0.0762779025227843 CG14362 CG14362 K06268|1|3e-08|58.5|cel:F59D6.7|protein phosphatase 3, regulatory subunit - - - 10178873 464.00 0.27 0.305 0.175849835399418 Up 0.0562343151499141 CG42824 CG42824 - - - - 318135 466.00 33.76 34.465 0.0298171112708888 Up 0.102199181085722 CG32640 CG32640 K09510|1|4e-16|83.2|tad:TRIADDRAFT_49929|DnaJ homolog subfamily B member 4;K09507|2|4e-15|79.7|xtr:493474|DnaJ homolog subfamily B member 1;K09515|4|7e-15|79.0|nve:NEMVE_v1g106836|DnaJ homolog subfamily B member 9 - GO:0005515//protein binding - 41552 2026.00 8.195 8.24 0.00790038808375941 Up 0.0472856954167217 CG18616 Not10 K12607|1|0.0|1088|dme:Dmel_CG18616|CCR4-NOT transcription complex subunit 10 - - - 7354474 1142.00 3.655 4.86 0.411084907653343 Up 0.319937921014397 CG42393 CG42393 - - - - 36615 2368.78 33.43 26.785 -0.319718058897764 Down 0.491249504688945 LamC lamin C, isoform B K07611|1|0.0|1104|dme:Dmel_CG10119|lamin B GO:0031967;GO:0005882//intermediate filament - GO:0000278//mitotic cell cycle;GO:0006997//nucleus organization 19835531 695.00 0.415 0.22 -0.915607812709627 Down 0.143805309734513 2768984 3294.00 0.58 0.415 -0.482941563780648 Down 0.121780478140272 CG33286 CG33286 - - - - 36939 1783.00 0.09 0.05 -0.84799690655495 Down 0.0698718795403513 CG17287 CG17287 - - - - 32740 924.23 145.875 163.5 0.164557979790734 Up 0.363690397569674 CG5703 CG5703, isoform B K03943|1|3e-130|464|dsi:Dsim_GD15675|NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0000166//nucleotide binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain;GO:0051234//establishment of localization 39780 1340.00 1.66 1.34 -0.308950240889153 Down 0.156716417910448 CG13054 CG13054 - - - - 41802 1510.00 14.325 12.24 -0.226931580951616 Down 0.335292563730022 CG7265 CG7265 - - - - 3772511 647.00 2.21 2.605 0.237237002887077 Up 0.162296922467309 CG33667 CG33667 - - - - 2768951 2227.00 8.985 10.635 0.243229624450731 Up 0.313102628450667 CG33217 CG33217 - - - - 35788 1638.00 19.035 16.58 -0.199210563066512 Down 0.333707568352926 Pabp2 Pabp2, isoform B K02163|1|2e-53|210|cfa:490611|apoptosis regulator BCL-W;K13044|3|4e-07|56.2|api:100165781|heterogeneous nuclear ribonucleoprotein A/B/D;K13195|4|5e-07|55.8|hmg:100201184|cold-inducible RNA-binding protein GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0003729//mRNA binding;GO:0005515//protein binding GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000377;GO:0031124//mRNA 3'-end processing;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000377;GO:0031124//mRNA 3'-end processing 40757 1129.00 0.04 0.425 3.4093909361377 Up 0.267071721040814 Osi3 osiris 3, isoform B - - - - 36354 990.00 0.755 0.365 -1.04858018044506 Down 0.218960507198521 Cpr49Ah cuticular protein 49Ah - - GO:0005198//structural molecule activity - 19834936 4982.00 0.695 0.665 -0.0636586372223179 Down 0.0489697530048871 36283 4671.00 1.5 1.815 0.27500704749987 Up 0.149253731343284 otk off-track, isoform B K05127|1|0.0|1920|dme:Dmel_CG8967|PTK7 protein tyrosine kinase 7 [EC:2.7.10.1] GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0005102//receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0007411//axon guidance;GO:0006464//cellular protein modification process 37840 6401.00 6.2 6.195 -0.00116393313363591 Down 0.0382380134724607 IntS1 integrator 1 K13138|1|0.0|4024|dme:Dmel_CG3173|integrator complex subunit 1 - - - 38733 2198.00 4.96 5.45 0.135916109277413 Up 0.15975432571655 CG10147 CG10147, isoform B K09228|1|6e-40|165|hsa:7639|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 33717 1194.00 32.25 35.09 0.121760787204188 Up 0.26505745608242 CG3792 CG3792 K09660|1|5e-128|457|dme:Dmel_CG3792|mannose-P-dolichol utilization defect 1 GO:0031224//intrinsic to membrane - - 41846 1740.42 1.54 3.875 1.3312659594667 Up 0.509708096684718 CG14864 CG14864, isoform B - - - - 19835512 790.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 41026 2461.75 20.19 21.975 0.122222254699293 Up 0.241876898692379 CG8032 CG8032, isoform B K12259|1|2e-81|303|tgu:100232049|spermine oxidase [EC:1.5.3.16] - GO:0003824//catalytic activity - 19835843 1035.00 0.225 0.09 -1.32192809488736 Down 0.129540351340642 31949 2236.60 46.495 39.4 -0.238879949699157 Down 0.431911240258883 CG15309 CG15309, isoform E - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - 19835435 555.00 0.525 0.72 0.455679483776189 Up 0.128384625544842 36199 2908.42 11.35 12.975 0.193042241066966 Up 0.288304054946506 CG9062 CG9062, isoform C K01062|1|2e-26|121|cqu:CpipJ_CPIJ001448|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0043231//intracellular membrane-bounded organelle - - 31741 2017.00 2.08 2.35 0.176077228423907 Up 0.125313697001717 CG2129 CG2129 K09228|1|9e-43|175|ptr:742564|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 41882 2198.05 27.93 24.24 -0.204425874806999 Down 0.363129045040285 CG6125 CG6125, isoform C K13962|1|4e-28|126|tgu:100223009|solute carrier family 26 (sulfate anion transporter), member 7;K03321|5|3e-15|84.0|rno:64076|sulfate permease, SulP family - - - 5740813 1353.01 0.91 0.91 3.20342650381492e-16 Up 0.0382380134724607 CG34447 CG34447, isoform B K01046|1|8e-33|141|tca:657679|triacylglycerol lipase [EC:3.1.1.3] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 37408 492.90 1.745 2.35 0.429433720355347 Up 0.230682868841633 CG15657 CG15657, isoform B - - - - 19834995 370.00 8.47 3.985 -1.08778224534173 Down 0.59001452912429 19834890 723.00 5.425 5.055 -0.101912045428827 Down 0.126469422797517 41034 1526.27 33.53 23.87 -0.490253916712008 Down 0.584202879408268 Cks85A Cyclin-dependent kinase subunit 85A, isoform C K02219|1|8e-38|156|dan:Dana_GF16842|cyclin-dependent kinase regulatory subunit CKS1 - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019887//protein kinase regulator activity GO:0000087//M phase of mitotic cell cycle 12797938 368.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 CG43407 CG43407, isoform B - - - - 33766 2054.00 24.325 32.825 0.432355206111775 Up 0.556366398098006 CG12512 CG12512 K01897|1|0.0|1186|dme:Dmel_CG12512|long-chain acyl-CoA synthetase [EC:6.2.1.3];K01904|4|5e-48|192|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12] GO:0015630//microtubule cytoskeleton GO:0003824//catalytic activity - 3354925 1450.21 107.985 118.38 0.132594437733927 Up 0.31221106855105 Maf1 Maf1, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0032559;GO:0003676//nucleic acid binding;GO:0032559;GO:0003676//nucleic acid binding;GO:0032559;GO:0003676//nucleic acid binding;GO:0032559 GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0006359//regulation of transcription from RNA polymerase III promoter 38221 2312.99 30.85 25.485 -0.275622136131404 Down 0.449049002773742 Gk glycerol kinase, isoform F K00864|1|0.0|1164|dme:Dmel_CG7995|glycerol kinase [EC:2.7.1.30] - GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process 31171 2664.00 11.75 11.855 0.0128349060296458 Up 0.0555739004094571 CG4281 CG4281 - - - - 42522 2329.00 0.065 0.11 0.758991900496205 Up 0.0694426099590543 CG5892 CG5892 K00680|1|9e-175|613|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 117336 1227.00 0.105 0.04 -1.39231742277876 Down 0.0864152687887994 Gr98c gustatory receptor 98c K08471|1|0.0|800|dme:Dmel_CG31060|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 19835626 1237.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 19835155 754.00 0.12 0.12 0 - 0.0382380134724607 19835553 1946.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 31056 4399.49 18.075 17.88 -0.0156489106551627 Down 0.0696077136441685 CG3655 CG3655, isoform D - - - - 41907 1578.00 20.55 21.12 0.0394714407894079 Up 0.111279883767006 CG9590 CG9590 - - - - 36128 1161.66 47.995 43.57 -0.139549004019622 Down 0.307125875049531 CG12338 CG12338, isoform B K00272|1|0.0|660|dme:Dmel_CG12338|D-aspartate oxidase [EC:1.4.3.1] - GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0008152//metabolic process 35449 1434.44 0.05 0.28 2.48542682717024 Up 0.184387795535596 Ir40a ionotropic receptor 40a, isoform G K05313|1|1e-08|62.0|cel:B0280.12|glutamate receptor, ionotropic, invertebrate GO:0044464//cell part GO:0005215//transporter activity - 33993 1513.00 0.085 0.04 -1.08746284125034 Down 0.0796790384361379 CG11289 CG11289 K00699|1|0.0|1031|dme:Dmel_CG11289|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 19836146 201.00 0.735 0.285 -1.36678233067162 Down 0.244947827235504 38438 4508.59 100.02 106.81 0.0947582143489163 Up 0.234645357284375 CG32264 CG32264, isoform M - - - - 32793 1518.00 23.87 45.62 0.934467880230361 Up 0.694657244749703 CG7135 CG7135 - - - - 38639 1152.00 0.38 0.165 -1.20353339408513 Down 0.161867652886012 lin-28 lin-28 K09276|1|2e-10|67.0|xla:379054|Y-box-binding protein 1;K09277|3|2e-10|66.6|ptr:455231|Y-box-binding protein 2 GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0045165//cell fate commitment;GO:0010586//miRNA metabolic process 34817 1766.00 90.715 66.605 -0.445710640803771 Down 0.607515519746401 Cyp28a5 Cyp28a5 K00517|1|0.0|998|dme:Dmel_CG8864| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding - 19835451 262.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 39812 944.71 2756.92 3453.675 0.325074923824889 Up 0.563928146876238 Pdh photoreceptor dehydrogenase, isoform D K00069|1|2e-36|152|rno:79242|15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006909//phagocytosis;GO:0001523//retinoid metabolic process;GO:0006909//phagocytosis;GO:0001523//retinoid metabolic process;GO:0006909//phagocytosis;GO:0001523//retinoid metabolic process;GO:0006909//phagocytosis;GO:0001523//retinoid metabolic process 19835942 807.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 38955 2414.60 10.3 11.01 0.0961701314937882 Up 0.167613261127988 mkg-p monkey king protein, isoform D K00970|1|8e-13|75.9|dme:Dmel_CG15737|poly(A) polymerase [EC:2.7.7.19];K13291|2|4e-12|73.6|ecb:100050669|terminal uridylyltransferase [EC:2.7.7.52] GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046914//transition metal ion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation;GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation 33875 877.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 CG13983 CG13983 - - - - 43516 1130.00 15.395 17.985 0.224332292090563 Up 0.350878351604808 CG7789 CG7789 K01082|1|2e-177|621|dme:Dmel_CG7789|3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] - GO:0016791//phosphatase activity - 43786 2834.04 40.615 40.82 0.00726353799017748 Up 0.0608572183331132 CG2177 Zinc/iron regulated transporter-related protein 102B, isoform F - - - - 31601 1825.39 33.635 26.525 -0.342610507029227 Down 0.506868313300753 Ctr1A copper transporter 1A, isoform D - - - - 19836112 537.00 0.55 1.27 1.20732497324751 Up 0.304781402720909 43312 6283.59 51.505 57.43 0.157092068747341 Up 0.341203275657113 wdb widerborst, isoform F K11584|1|0.0|771|dya:Dyak_GE10557|protein phosphatase 2 (formerly 2A), regulatory subunit B' GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0019888//protein phosphatase regulator activity GO:0007051//spindle organization;GO:0023060;GO:0007051//spindle organization;GO:0023060;GO:0007051//spindle organization;GO:0023060;GO:0007051//spindle organization;GO:0023060;GO:0007051//spindle organization;GO:0023060 33790 1482.00 0.44 0.63 0.517848304862619 Up 0.130530973451327 CG14011 CG14011, isoform C - - - - 38465 588.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG10853 CG10853 - - - - 43461 1233.00 0.79 0.59 -0.421137698815262 Down 0.129210143970413 CG14507 CG14507 K01047|1|0.0|721|dme:Dmel_CG14507|phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 246645 859.00 0.37 0.26 -0.509013647487857 Down 0.100779289393739 CG30486 CG30486, isoform B - - - - 318658 1491.00 1.55 2.78 0.84281666744927 Up 0.36828028001585 Tpl94D transition protein-like 94D, isoform B - - - - 34240 1021.00 17.815 26.1 0.550957323323948 Up 0.589684321754062 CG13108 CG13108 - - - - 35084 5476.00 9.775 9.015 -0.116769210762373 Down 0.184024567428345 kel kelch, isoform B K10443|1|0.0|1235|dme:Dmel_CG7210|kelch-like protein 2/3 GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal;GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0016477//cell migration;GO:0007293//germarium-derived egg chamber formation;GO:0051276//chromosome organization;GO:0007010//cytoskeleton organization;GO:0007275//multicellular organismal development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0016477//cell migration;GO:0007293//germarium-derived egg chamber formation;GO:0051276//chromosome organization;GO:0007010//cytoskeleton organization;GO:0007275//multicellular organismal development;GO:0007300//ovarian nurse cell to oocyte transport 317891 807.75 9.825 10.205 0.0547468698867505 Up 0.106392814687624 CG32163 CG32163, isoform B - - GO:0016407//acetyltransferase activity - 34259 871.00 1.42 1.44 0.02017788193763 Up 0.0440166424514595 Fbp2 Fat body protein 2, isoform C K00001|1|2e-25|116|dwi:Dwil_GK18290|alcohol dehydrogenase [EC:1.1.1.1] GO:0044444//cytoplasmic part GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0008152//metabolic process 43944 3280.00 28.505 35.76 0.327131735050256 Up 0.502443534539691 sbr small bristles K10411|1|9e-06|53.1|tad:TRIADDRAFT_56121|dynein light chain 1, axonemal GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0016020//membrane GO:0005488//binding GO:0007613//memory;GO:0006811//ion transport;GO:0031124//mRNA 3'-end processing;GO:0006406//mRNA export from nucleus 318228 2215.12 0.835 0.325 -1.3613364794456 Down 0.262184651961432 CG32820 CG32820, isoform B K04688|1|2e-19|97.4|aag:AaeL_AAEL000743|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization 32971 6587.85 4.015 6.565 0.709395023375572 Up 0.475927882710342 CG14215 CG14215, isoform B - - - - 12798533 700.53 13.195 13.32 0.0136027317449938 Up 0.0563994188350284 318572 818.00 1.46 1.285 -0.184200009686139 Down 0.100515123497556 CG31053 CG31053 - - GO:0046914//transition metal ion binding - 50438 867.57 9.745 13.19 0.436710473993655 Up 0.476225069343548 CG18661 CG18661, isoform B - - - - 38176 4811.69 25.665 26.86 0.0656570442168729 Up 0.1670519085986 CG12090 CG12090, isoform E - - - - 41871 1080.78 11.8 12.165 0.0439494606892252 Up 0.0987650244353454 Trax translin associated factor X, isoform B - - - - 43023 3384.92 2.76 3.645 0.401250547548768 Up 0.276218465196143 dan distal antenna, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0001654//eye development;GO:0010468//regulation of gene expression;GO:0007389//pattern specification process 31556 1561.78 3.825 3.535 -0.113749532770615 Down 0.115275392946771 CG14445 CG14445, isoform D - - - - 31273 915.00 0.085 0.305 1.84327449631255 Up 0.172071060626073 CG14416 CG14416 - - - - 33858 755.74 9.385 9.06 -0.0508456947846393 Down 0.100944393078854 CG9154 CG9154, isoform B - - GO:0005488//binding;GO:0016741 GO:0006730//one-carbon metabolic process 19835481 1162.00 5.535 6.225 0.169490520173891 Up 0.197596090344736 39657 1343.00 10.105 9.4 -0.104336659814736 Down 0.166919825650509 CG7011 CG7011 - GO:0044464//cell part - - 40111 3066.00 0.04 0.165 2.04439411935845 Up 0.1267335886937 Chd3 Chd3 K11643|1|0.0|1152|dme:Dmel_CG8103|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.1.-] GO:0044427//chromosomal part;GO:0000118//histone deacetylase complex GO:0003678//DNA helicase activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding;GO:0032559 GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0034728//nucleosome organization 8674019 1529.00 25.49 23.97 -0.0887014643730689 Down 0.198817857614582 mtTFB1 mitochondrial transcription factor B1 K02528|1|3e-14|80.1|mmu:66254|dimethyladenosine transferase [EC:2.1.1.-] GO:0031980 GO:0008173//RNA methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0008134//transcription factor binding GO:0006412//translation;GO:0006364//rRNA processing;GO:0006351//transcription, DNA-dependent 32543 2817.71 32.965 32.975 0.000437578117060542 Up 0.0401862369568089 Myb Myb oncogene-like, isoform E K09420|1|0.0|1271|dme:Dmel_CG9045|myb proto-oncogene protein;K09421|3|0.0|663|dvi:Dvir_GJ18431|myb-related protein GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0000790//nuclear chromatin GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0031023//microtubule organizing center organization;GO:0051276//chromosome organization;GO:0010468//regulation of gene expression;GO:0051301//cell division;GO:0007067//mitosis;GO:0006351//transcription, DNA-dependent;GO:0006277//DNA amplification;GO:0031023//microtubule organizing center organization;GO:0051276//chromosome organization;GO:0010468//regulation of gene expression;GO:0051301//cell division;GO:0007067//mitosis;GO:0006351//transcription, DNA-dependent;GO:0006277//DNA amplification;GO:0031023//microtubule organizing center organization;GO:0051276//chromosome organization;GO:0010468//regulation of gene expression;GO:0051301//cell division;GO:0007067//mitosis;GO:0006351//transcription, DNA-dependent;GO:0006277//DNA amplification;GO:0031023//microtubule organizing center organization;GO:0051276//chromosome organization;GO:0010468//regulation of gene expression;GO:0051301//cell division;GO:0007067//mitosis;GO:0006351//transcription, DNA-dependent;GO:0006277//DNA amplification 38583 1074.45 9.285 9.505 0.0337847167131312 Up 0.0779949808479725 CG13707 CG13707, isoform D - - - - 43434 3325.00 10.505 11.205 0.0930664868373474 Up 0.160348698982961 Cul-5 cullin 5 K10612|1|0.0|1281|dme:Dmel_CG1401|cullin 5 GO:0000151//ubiquitin ligase complex GO:0019899//enzyme binding GO:0001709//cell fate determination;GO:0048741//skeletal muscle fiber development;GO:0019941//modification-dependent protein catabolic process 19835401 302.00 1.065 0.865 -0.300081392589113 Down 0.121780478140272 12798222 337.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 37986 2012.07 22.32 15.195 -0.554740352306893 Down 0.578028001584995 CG30427 CG30427, isoform G K13356|1|0.0|787|dsi:Dsim_GD24908|fatty acyl-CoA reductase [EC:1.2.1.-] - - GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis 30986 2279.00 78.805 120.19 0.608957793056606 Up 0.665103685114252 Cyp4g1 cytochrome P450-4g1 K00517|1|0.0|1065|dme:Dmel_CG3972| [EC:1.14.-.-];K07427|3|2e-81|303|xtr:780124|cytochrome P450, family 4, subfamily V - - - 46038 1413.13 88.16 89.68 0.0246620542342693 Up 0.0903117157574957 l(2)03709 prohibitin 2, isoform F - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - - 318916 3492.54 33.42 36.475 0.126196244744065 Up 0.281699907541936 CG33181 CG33181, isoform J - - GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport 42866 1459.37 7.38 7.01 -0.0742063720497729 Down 0.114614978206314 Mpk2 p38a MAP kinase, isoform C K04441|1|0.0|746|dme:Dmel_CG5475|p38 MAP kinase [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004707//MAP kinase activity;GO:0032559;GO:0004707//MAP kinase activity;GO:0032559;GO:0004707//MAP kinase activity;GO:0032559 GO:0007472//wing disc morphogenesis;GO:0002759//regulation of antimicrobial humoral response;GO:0007243//intracellular protein kinase cascade;GO:0030509//BMP signaling pathway;GO:0006970//response to osmotic stress;GO:0031347//regulation of defense response;GO:0002251;GO:0006464//cellular protein modification process;GO:0007472//wing disc morphogenesis;GO:0002759//regulation of antimicrobial humoral response;GO:0007243//intracellular protein kinase cascade;GO:0030509//BMP signaling pathway;GO:0006970//response to osmotic stress;GO:0031347//regulation of defense response;GO:0002251;GO:0006464//cellular protein modification process;GO:0007472//wing disc morphogenesis;GO:0002759//regulation of antimicrobial humoral response;GO:0007243//intracellular protein kinase cascade;GO:0030509//BMP signaling pathway;GO:0006970//response to osmotic stress;GO:0031347//regulation of defense response;GO:0002251;GO:0006464//cellular protein modification process 39760 1533.00 0.535 0.765 0.515920856291505 Up 0.142616563201691 CG13074 CG13074 - - - - 39661 1694.00 0.025 0.18 2.84799690655495 Up 0.158037247391362 Best3 bestrophin 3 K13880|1|2e-95|350|xtr:100302039|bestrophin-3;K13879|2|3e-95|349|xtr:394571|bestrophin-2;K13881|4|4e-94|345|xtr:100144681|bestrophin-4 - - - 5740675 140.00 0.45 0.01 -5.49185309632967 Down 0.339420155857879 38479 2704.00 31.17 20.375 -0.613358095619566 Down 0.617685906749439 CG1136 CG1136 - - GO:0005198//structural molecule activity - 34792 3679.00 1.35 1.335 -0.0161196653632771 Down 0.0440166424514595 tam tamas K02332|1|0.0|2211|dme:Dmel_CG8987|DNA polymerase gamma 1 [EC:2.7.7.7] GO:0005759//mitochondrial matrix GO:0003676//nucleic acid binding;GO:0034061;GO:0008408//3'-5' exonuclease activity GO:0006261//DNA-dependent DNA replication;GO:0010259//multicellular organismal aging 33780 2148.00 20.295 20.72 0.0298996629888604 Up 0.0937458724078721 CG14015 CG14015 K01238|1|1e-30|134|dre:566679| [EC:3.2.1.-] - - - 30984 1310.00 0.415 0.315 -0.397759507847008 Down 0.0941421212521464 pcl pepsinogen-like K01379|1|6e-81|301|ame:409341|cathepsin D [EC:3.4.23.5] - - - 36597 902.00 2.86 5.745 1.00629174586772 Up 0.525128780874389 Arc2 Arc2 - - GO:0005488//binding GO:0042594//response to starvation 32813 2443.00 0.065 0.02 -1.70043971814109 Down 0.0744287412495047 os outstretched, isoform C - GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0005102//receptor binding;GO:0005102//receptor binding GO:0017145//stem cell division;GO:0008360//regulation of cell shape;GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0003382//epithelial cell morphogenesis;GO:0010740//positive regulation of intracellular protein kinase cascade;GO:0007281//germ cell development;GO:0042074//cell migration involved in gastrulation;GO:0007560//imaginal disc morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0006950//response to stress;GO:0017145//stem cell division;GO:0008360//regulation of cell shape;GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0003382//epithelial cell morphogenesis;GO:0010740//positive regulation of intracellular protein kinase cascade;GO:0007281//germ cell development;GO:0042074//cell migration involved in gastrulation;GO:0007560//imaginal disc morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0006950//response to stress 37556 2972.22 39.565 40.91 0.0482287800018822 Up 0.142979791308942 CG13506 CG13506, isoform B K12567|1|5e-14|80.5|rno:84015|titin [EC:2.7.11.1] - - - 40557 1533.42 26.365 26.925 0.0303223480517371 Up 0.0988310659093911 CG9853 CG9853, isoform C - - - - 33502 1868.84 17.075 18.625 0.125354847059433 Up 0.243098665962224 CG9641 CG9641, isoform B - - - - 35707 1206.03 15.27 9.78 -0.642793691844618 Down 0.5683529256373 CG2065 CG2065, isoform B K00100|1|3e-113|408|dme:Dmel_CG2070| [EC:1.1.1.-];K11153|2|7e-79|294|gga:423274|retinol dehydrogenase 12 [EC:1.1.1.-];K11161|5|5e-74|278|hsa:112724|retinol dehydrogenase 13 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 38357 3830.52 3.345 4.66 0.47832374401282 Up 0.34500066041474 FR FMRFamide receptor, isoform C K04282|1|8e-12|73.2|mdo:100024485|thyrotropin-releasing hormone receptor;K08430|3|9e-11|69.7|dre:100000501|G protein-coupled receptor 142 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway 42273 1235.27 11.31 10.44 -0.115477217419936 Down 0.192676000528332 dnk deoxyribonucleoside kinase, isoform B K05961|1|3e-143|508|dme:Dmel_CG5452| [EC:2.7.1.145];K00857|2|3e-142|504|dsi:Dsim_GD19261|thymidine kinase [EC:2.7.1.21] GO:0043231//intracellular membrane-bounded organelle GO:0032559;GO:0019136//deoxynucleoside kinase activity GO:0006796//phosphate-containing compound metabolic process;GO:0009174;GO:0009132//nucleoside diphosphate metabolic process 14462528 826.25 2.05 4.7 1.19703684705955 Up 0.522255976753401 32468 11059.18 19.235 26.05 0.437549542869256 Up 0.544875181614054 cngl cyclic nucleotide-gated ion channel-like, isoform J K04949|1|9e-117|422|spu:579326|cyclic nucleotide gated channel alpha 2;K04950|2|6e-116|420|tgu:100222773|cyclic nucleotide gated channel alpha 3 GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity GO:0006810//transport 34728 1044.00 708.485 425.765 -0.734679950858889 Down 0.704530445119535 CG5867 CG5867 - - - - 41242 3018.16 2.015 3.245 0.687438639471171 Up 0.354708757099458 CG6241 TATA box-binding protein-associated factor RNA polymerase I subunit B, isoform C K13051|1|4e-40|167|ame:552839|beta-aspartyl-peptidase (threonine type) [EC:3.4.19.5] - - - 34187 1540.00 7.625 6.685 -0.189809777244258 Down 0.233126403381323 CG13090 CG13090, isoform C K11996|1|0.0|904|dme:Dmel_CG13090|adenylyltransferase and sulfurtransferase MOCS3/UBA4 [EC:2.7.7.- 2.8.1.-] GO:0044444//cytoplasmic part GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding;GO:0016783//sulfurtransferase activity;GO:0032559 GO:0044267//cellular protein metabolic process;GO:0009108//coenzyme biosynthetic process;GO:0006400//tRNA modification 37708 3990.00 3.97 3.87 -0.0368054409985473 Down 0.0640272090873068 CG3520 CG3520 - - - - 36768 2317.53 45.38 32.105 -0.499258610308602 Down 0.602463346981905 CG8399 CG8399, isoform B K12589|1|1e-161|570|dse:Dsec_GM21652|exosome complex component RRP42 GO:0031224//intrinsic to membrane GO:0003676//nucleic acid binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0008408//3'-5' exonuclease activity GO:0010467//gene expression;GO:0006547//histidine metabolic process 12798545 13834.00 0.06 0.095 0.662965012722429 Up 0.0688152159556201 42647 684.21 39.155 41.795 0.0941338128152072 Up 0.218663320565315 CG7048 CG7048, isoform B K04797|1|7e-74|276|dme:Dmel_CG7048|prefoldin alpha subunit GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 19835192 564.00 1.515 0.595 -1.34835622016501 Down 0.348897107383437 40415 692.00 17.655 16.365 -0.109463218714837 Down 0.21304979527143 Rpb8 Rpb8 K03016|1|1e-83|308|dya:Dyak_GE19787|DNA-directed RNA polymerase II subunit H GO:0016591//DNA-directed RNA polymerase II, holoenzyme GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0016301//kinase activity GO:0006396//RNA processing;GO:0006354//DNA-dependent transcription, elongation;GO:0006352//DNA-dependent transcription, initiation 34627 1440.91 41.045 36.82 -0.156716860490646 Down 0.329414872539955 CG14946 CG14946, isoform E K11151|1|3e-40|167|cfa:486998|retinol dehydrogenase 10 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 42374 1917.00 0.06 0.725 3.59494658929378 Up 0.351736890767402 CG4465 CG4465 K08216|1|2e-13|77.4|mmu:381203|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 20;K08202|2|5e-13|76.3|bfo:BRAFLDRAFT_257702|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5;K08209|3|7e-13|75.9|gga:420422|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13 - - GO:0006810//transport 35737 1469.05 47.795 49.915 0.0626137254682367 Up 0.167712323339057 CG12822 CG12822, isoform B K01669|1|4e-83|308|dme:Dmel_CG18853|deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] - - - 251924 456.00 3.63 3.365 -0.109363043385434 Down 0.111312904504029 CG32148 CG32148 - - - - 42774 1764.00 0.09 0.195 1.11547721741994 Up 0.107647602694492 CG10170 CG10170 K00699|1|5e-121|434|dpo:Dpse_GA18421|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 5740170 444.00 32.385 4.04 -3.00289854599187 Down 0.797087570994585 CG34215 CG34215 - - - - 34874 800.00 9.58 11.925 0.315891705156694 Up 0.39330999867917 l(2)35Be lethal (2) 35Be K10380|1|7e-14|77.4|dvi:Dvir_GJ19213|ankyrin - - - 42971 2883.00 0.32 0.485 0.599912842187128 Up 0.121681415929204 CycB3 cyclin B3, isoform B K05868|1|0.0|1032|dme:Dmel_CG5814|cyclin B GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0033205//cell cycle cytokinesis;GO:0000087//M phase of mitotic cell cycle 43550 11469.00 2.4 3.35 0.481126689736616 Up 0.294412891295734 CG15523 CG15523, isoform B - - - - 43008 1496.00 5.53 6.235 0.173110079594963 Up 0.198982961299696 CG9996 CG9996 K13676|1|0.0|731|dme:Dmel_CG9996|UDP-xylose:glucoside alpha-1,3-xylosyltransferase [EC:2.4.1.-] - GO:0016740//transferase activity - 43980 1590.91 2.035 4.26 1.06582463595959 Up 0.485338792761854 Lip2 lipase 2, isoform B K01066|1|5e-45|182|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01046|2|6e-40|165|dpo:Dpse_GA20265|triacylglycerol lipase [EC:3.1.1.3] - - GO:0044238//primary metabolic process 12798530 596.00 0.07 0.08 0.192645077942396 Up 0.045898824461762 CG43403 CG43403 - - - - 35106 5187.00 16.26 8.5 -0.935792511049964 Down 0.635979395060098 CG10211 CG10211, isoform B K10789|1|2e-95|351|gga:417467|myeloperoxidase [EC:1.11.1.7];K00430|3|1e-93|345|cel:F09F3.5|peroxidase [EC:1.11.1.7] - GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0016740//transferase activity GO:0008152//metabolic process;GO:0006950//response to stress 35720 1189.00 0.495 0.405 -0.289506617194985 Down 0.0859199577334566 CG1946 CG1946 K11172|1|2e-47|189|mcc:694889|diacylglycerol O-acyltransferase 2-like protein 6 [EC:2.3.1.-];K11160|2|5e-47|188|mdo:100011089|diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.76] - GO:0016746//transferase activity, transferring acyl groups - 40224 4071.85 42.465 61.7 0.538996239409877 Up 0.629474309866596 rdgC retinal degeneration C, isoform H K13807|1|0.0|1274|dse:Dsec_GM22268|retinal degeneration C protein [EC:3.1.3.16] - GO:0046914//transition metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding GO:0009586;GO:0019932//second-messenger-mediated signaling;GO:0009266//response to temperature stimulus;GO:0043954//cellular component maintenance;GO:0006464//cellular protein modification process;GO:0009586;GO:0019932//second-messenger-mediated signaling;GO:0009266//response to temperature stimulus;GO:0043954//cellular component maintenance;GO:0006464//cellular protein modification process;GO:0009586;GO:0019932//second-messenger-mediated signaling;GO:0009266//response to temperature stimulus;GO:0043954//cellular component maintenance;GO:0006464//cellular protein modification process;GO:0009586;GO:0019932//second-messenger-mediated signaling;GO:0009266//response to temperature stimulus;GO:0043954//cellular component maintenance;GO:0006464//cellular protein modification process 41263 2407.00 0.465 0.045 -3.36923380966572 Down 0.276317527407212 CG12592 CG12592 - GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton - GO:0006997//nucleus organization 33348 699.83 21.34 25.895 0.279113382306424 Up 0.436798309338264 mRpL48 mitochondrial ribosomal protein L48, isoform B - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 34478 979.00 0.91 1.29 0.503432615224558 Up 0.18663320565315 CG17118 CG17118 - GO:0043231//intracellular membrane-bounded organelle - GO:0048812//neuron projection morphogenesis 41910 547.80 34.55 31.62 -0.12784834291725 Down 0.280180953638885 Acyp2 acylphosphatase 2, isoform B K01512|1|5e-55|212|dme:Dmel_CG18505|acylphosphatase [EC:3.6.1.7] - - - 31649 916.61 9.295 8.645 -0.1045889012772 Down 0.161669528463875 CG4593 CG4593, isoform B - - - - 30979 3376.02 34.205 11.275 -1.60107979654148 Down 0.740622110685511 CG3777 CG3777, isoform E - - - - 43800 2390.42 112.505 118.31 0.0725829009700868 Up 0.195879012019548 CG1909 CG1909, isoform B - - - - 8673971 640.00 0.75 0.91 0.278975949702815 Up 0.107416457535332 Sfp38D seminal fluid protein 38D, isoform B - - - - 12798311 428.00 0.01 0.225 4.49185309632967 Up 0.222989037115308 12798359 980.00 4.12 4.26 0.0482090930426198 Up 0.0730748910315678 40434 2772.69 227.865 263.34 0.208747331964295 Up 0.437590807026813 P5CDh1 delta-1-Pyrroline-5-carboxylate dehydrogenase 1, isoform F K00294|1|0.0|1117|dme:Dmel_CG7145|1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.1.12] GO:0031980;GO:0031980;GO:0031980;GO:0031980 GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0006560//proline metabolic process;GO:0006560//proline metabolic process;GO:0006560//proline metabolic process;GO:0006560//proline metabolic process 39109 1497.00 0.08 0.09 0.169925001442312 Up 0.045667679302602 Or67a odorant receptor 67a K08471|1|0.0|817|dme:Dmel_CG12526|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 2768969 742.00 1.94 4.335 1.15997534103471 Up 0.503566239598468 CG33267 CG33267 - - - - 42614 973.03 208.445 191.95 -0.118936206244389 Down 0.299035794478933 rdhB retinol dehydrogenase B, isoform B K11539|1|4e-16|85.5|xla:414681|carbonyl reductase 4 [EC:1.1.1.-];K11166|2|2e-15|83.2|mmu:216820|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-];K00120|3|2e-15|82.8|dme:Dmel_CG31937| [EC:1.1.-.-];K11150|4|7e-15|81.3|dre:280648|retinol dehydrogenase 8 [EC:1.1.1.-];K11165|5|7e-15|81.3|bta:514044|dehydrogenase/reductase SDR family member 7 [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 35615 1347.00 41.87 40.455 -0.0495988957835427 Down 0.143739268260468 Tsp42Ef tetraspanin 42Ef K06497|1|1e-15|84.3|dme:Dmel_CG18817|CD63 antigen GO:0031224//intrinsic to membrane - - 2768906 607.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 Ste:CG33245 Ste:CG33245 K08282|1|2e-95|347|dme:Dmel_CG33236|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 33672 591.00 0.55 0.58 0.0766212816029127 Up 0.0499273543785497 Taf12L TBP-associated factor 30kD subunit alpha-2 K03126|1|1e-05|49.7|dre:386637|transcription initiation factor TFIID subunit D10 GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007126//meiosis;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent 19835616 357.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 41441 7255.00 12.68 13.945 0.137193188888905 Up 0.236923788138951 Cad87A cadherin 87A K06813|1|1e-128|462|dre:407978|cadherin 23 GO:0031224//intrinsic to membrane GO:0046872//metal ion binding GO:0016337//cell-cell adhesion;GO:0032501//multicellular organismal process 31703 1705.00 79.24 89.91 0.182252704345244 Up 0.383304715361247 CG1444 CG1444 K00100|1|7e-166|583|dme:Dmel_CG1444| [EC:1.1.1.-];K00044|2|3e-62|239|xtr:549988|estradiol 17beta-dehydrogenase [EC:1.1.1.62];K10251|2|3e-62|239|xtr:549988|beta-keto reductase [EC:1.1.1.-] - - - 31777 1044.00 11.415 10.32 -0.145487888801447 Down 0.230055474838198 CG12123 CG12123 - - - - 36696 1204.00 6.76 7.775 0.201819428735781 Up 0.245112930920618 CG8152 CG8152 K10380|1|2e-08|60.5|dre:568926|ankyrin GO:0044464//cell part GO:0005488//binding - 31399 1187.75 22.685 22.16 -0.0337807783015562 Down 0.0979064852727513 Torsin torsin, isoform B K03695|1|8e-14|78.2|rno:65041|ATP-dependent Clp protease ATP-binding subunit ClpB GO:0044432//endoplasmic reticulum part GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0051084//'de novo' posttranslational protein folding 19836038 872.00 0.955 0.735 -0.377756483199384 Down 0.133436798309338 3355094 2075.25 47.295 43.885 -0.107959763409268 Down 0.25660414740457 CG12567 CG12567, isoform G K06672|1|8e-147|521|der:Dere_GG21418|cohesin loading factor subunit SCC2 GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0007064//mitotic sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion 40656 1122.00 19.5 20.48 0.070741591363027 Up 0.158763703605864 mRpL44 mitochondrial ribosomal protein L44 K03685|1|7e-07|55.1|nve:NEMVE_v1g10066|ribonuclease III [EC:3.1.26.3] GO:0005622//intracellular GO:0003723//RNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0005198//structural molecule activity GO:0010467//gene expression 31253 3051.59 13.205 14.28 0.112911677862007 Up 0.200369832254656 CG2658 CG2658, isoform C K09552|1|0.0|788|dme:Dmel_CG2658|spastic paraplegia 7 [EC:3.4.24.-] - - - 32739 1978.00 0.345 0.425 0.300866479359533 Up 0.0835094439307885 CG8316 CG8316, isoform B - - - - 37647 925.02 13.75 16.48 0.261284623883834 Up 0.379078061022322 CG9849 CG9849, isoform B K10086|1|4e-07|55.5|spu:579538|ER degradation enhancer, mannosidase alpha-like 3 - - GO:0001709//cell fate determination;GO:0001709//cell fate determination 19835296 1641.00 0.095 0.085 -0.160464672193246 Down 0.045238409721305 34661 1479.00 0.215 0.2 -0.104336659814736 Down 0.0473847576277902 CG5421 CG5421, isoform B K03662|1|9e-13|75.1|dme:Dmel_CG8029|V-type H+-transporting ATPase S1 subunit [EC:3.6.3.14] GO:0033176 GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process 39311 3030.00 25.075 26.32 0.0699097882356985 Up 0.168570862501651 CG32085 CG32085 K10282|1|0.0|1078|dme:Dmel_CG32085|F-box and leucine-rich repeat protein 16 - GO:0005488//binding - 246663 848.00 202.34 55.745 -1.85986723558016 Down 0.782723550389645 Prx2540-1 peroxiredoxin 2540-1 K00430|1|2e-128|457|dme:Dmel_CG12405|peroxidase [EC:1.11.1.7] GO:0044444//cytoplasmic part GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0019725//cellular homeostasis 41795 1695.00 0.63 0.795 0.335603031784439 Up 0.116034869898296 CG3610 CG3610 - - - - 38957 4766.00 2.77 2.42 -0.194878928774594 Down 0.145192180689473 Oseg1 outer segment 1, isoform B K02084|1|3e-12|74.7|oaa:100073402|apoptotic protease-activating factor GO:0042995//cell projection;GO:0044424//intracellular part - GO:0042384//cilium assembly 42671 1268.00 26.985 28.39 0.0732251617517533 Up 0.17180689472989 mRpL45 mitochondrial ribosomal protein L45 K10836|1|0.0|652|dme:Dmel_CG6949|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0030529//ribonucleoprotein complex GO:0008320//protein transmembrane transporter activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0015031//protein transport 31097 2046.78 9.41 11.1 0.238293048508931 Up 0.316305639941883 ns3 nucleostemin ortholog 3, isoform B - - - - 34811 1333.00 571.665 278.54 -1.03728544242222 Down 0.741612732796196 CG16885 CG16885 - - - - 31128 1115.00 0.205 0.35 0.771731012326883 Up 0.118544445912033 CG3795 CG3795, isoform B K01362|1|3e-173|607|dme:Dmel_CG3795| [EC:3.4.21.-];K01312|3|5e-30|131|mmu:436522|trypsin [EC:3.4.21.4] - - - 38740 2599.53 10.44 12.185 0.222984539153456 Up 0.311154404966319 CG8368 CG8368, isoform B K01175|1|3e-25|117|hsa:254958| [EC:3.1.-.-];K12579|3|4e-12|73.9|oaa:100093227|interferon-stimulated gene 20 kDa protein [EC:3.1.13.1] GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0004518//nuclease activity;GO:0005488//binding;GO:0004518//nuclease activity - 31694 1686.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 Ir7g ionotropic receptor 7g - - - - 12798121 688.00 0.235 0.21 -0.162271428898877 Down 0.0504556861709153 CG43115 CG43115 - - - - 36963 527.00 89.445 91.065 0.0258958364265841 Up 0.110388323867389 robl roadblock K10419|1|3e-48|190|dvi:Dvir_GJ20372|dynein light chain roadblock-type - - - 41278 1507.00 42.28 43.35 0.0360566167265143 Up 0.124224012679963 CG14683 CG14683 K00288|1|8e-06|52.0|dya:Dyak_GE26043|methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] GO:0044424//intracellular part GO:0004721//phosphoprotein phosphatase activity;GO:0008170//N-methyltransferase activity GO:0031167//rRNA methylation;GO:0006796//phosphate-containing compound metabolic process 33284 3074.55 33.715 36.21 0.102997579148099 Up 0.231970677585524 CG4629 CG4629, isoform F K08798|1|2e-58|228|dre:334300|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0065008;GO:0006464//cellular protein modification process;GO:0065008;GO:0006464//cellular protein modification process 35824 1826.00 9.435 6.535 -0.529835281805012 Down 0.471106855105006 Mal-A1 maltase A1 K01187|1|0.0|1207|dme:Dmel_CG8696|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding;GO:0015926//glucosidase activity GO:0019318//hexose metabolic process 12797926 1178.08 1.245 0.86 -0.533737177365983 Down 0.188317263241316 CG43085 CG43085, isoform B - - - - 19835807 567.00 0.36 0.01 -5.16992500144231 Down 0.301512349755647 42811 970.00 18.665 17.38 -0.10290742648867 Down 0.203440760797781 CG10214 CG10214 K13288|1|7e-121|433|dme:Dmel_CG10214|oligoribonuclease [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004518//nuclease activity - 44529 4525.48 23.5 23.875 0.0228399763581113 Up 0.079877162858275 ptr proximal to raf, isoform F K04574|1|7e-07|57.4|gga:417020|neurofilament heavy polypeptide;K14000|2|5e-06|54.7|xla:444366|ribosome-binding protein 1;K03626|3|6e-06|54.3|mmu:17938|nascent polypeptide-associated complex subunit alpha GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity - 33367 7066.55 42.98 40.505 -0.0855654752631296 Down 0.216715097080967 CG7337 CG7337, isoform H K03362|1|2e-16|89.4|nvi:100122997|F-box and WD-40 domain protein 1/11 - - - 37627 5636.58 8.05 6.91 -0.220303072613721 Down 0.264991414608374 CG13531 CG13531, isoform C - - - - 35511 2226.00 9.99 11.6 0.215568222222516 Up 0.302304847444195 CG7791 CG7791 K01410|1|0.0|1394|dme:Dmel_CG7791|mitochondrial intermediate peptidase [EC:3.4.24.59] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0051604//protein maturation 43442 2924.60 129.995 108.52 -0.2604951811834 Down 0.483126403381323 Vha100-1 vacuolar H[+] ATPase 100kD subunit 1, isoform K K02154|1|0.0|1606|dme:Dmel_CG1709|V-type H+-transporting ATPase subunit I [EC:3.6.3.14] GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex;GO:0016469//proton-transporting two-sector ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process 19834941 489.00 1.885 1.32 -0.514026593910211 Down 0.231310262845067 33294 999.00 4.115 3.215 -0.356073693093678 Down 0.273312640338132 Tfb4 TFB4 ortholog K03143|1|6e-166|583|dme:Dmel_CG5041|transcription initiation factor TFIIH subunit H3 GO:0005667//transcription factor complex;GO:0000441//SSL2-core TFIIH complex GO:0003702//RNA polymerase II transcription factor activity GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-dependent 36920 2168.00 3.715 2.815 -0.400227288458367 Down 0.278430854576674 tef teflon - - - - 3772206 543.00 0.23 0.09 -1.3536369546147 Down 0.129573372077665 CheA56a chemosensory protein A 56a - - - - 38078 1103.00 8.45 5.865 -0.526820233141038 Down 0.454266279223352 MED30 mediator complex subunit 30 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent 40994 1856.00 8.61 9.5 0.141914275821466 Up 0.207007000396249 CG9601 CG9601 K08073|1|0.0|1038|dme:Dmel_CG9601|bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] - - - 14462420 397.00 0.11 0.125 0.184424571137428 Up 0.0511161009113723 44132 1243.04 96.3 86.755 -0.150588890322144 Down 0.34093910976093 slmo slowmo, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0014821;GO:0007610//behavior;GO:0048232//male gamete generation;GO:0014821;GO:0007610//behavior;GO:0048232//male gamete generation;GO:0014821;GO:0007610//behavior;GO:0048232//male gamete generation;GO:0014821;GO:0007610//behavior;GO:0048232//male gamete generation 32726 2018.25 4.375 4.385 0.00329382572504181 Up 0.0401862369568089 CG5613 CG5613, isoform B K01227|1|8e-68|258|mdo:100030963|mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005488//binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005488//binding - 41365 946.00 26.075 26.69 0.0336320527348383 Up 0.0998547087570995 mgr merry-go-round - GO:0043234//protein complex GO:0005515//protein binding GO:0006457//protein folding 42678 559.00 0.82 0.68 -0.270089163367745 Down 0.0995575221238938 CG17625 CG17625 - - - - 19835910 629.00 0.195 0.155 -0.331205908475373 Down 0.0662726192048606 38573 641.00 0.45 0.85 0.917537839808027 Up 0.215856557918373 CG15876 CG15876 - - - - 38973 825.00 188.045 162.175 -0.213526507704977 Down 0.434486857746665 se sepia K00310|1|4e-133|473|dme:Dmel_CG6781|pyrimidodiazepine synthase [EC:1.5.4.1];K00799|1|4e-133|473|dme:Dmel_CG6781|glutathione S-transferase [EC:2.5.1.18] GO:0044424//intracellular part GO:0042802//identical protein binding;GO:0016648;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0019889//pteridine metabolic process;GO:0042441//eye pigment metabolic process 14462438 442.00 0.585 0.845 0.53051471669878 Up 0.15268788799366 33374 651.00 270.24 370.445 0.45501812812566 Up 0.631455554087967 Npc2a Niemann-Pick type C-2a K13443|1|2e-80|298|dme:Dmel_CG7291|Niemann-Pick C2 protein - - - 3355133 2142.36 39.48 45.245 0.196636379776817 Up 0.386243560956281 CG17082 conundrum, isoform I K08878|1|2e-10|67.8|bfo:BRAFLDRAFT_84243|breakpoint cluster region protein [EC:2.7.11.1];K12490|3|2e-09|64.7|cin:100169677|Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein;K10360|4|1e-08|62.4|cel:F56A6.2|myosin IX GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - GO:0023060;GO:0023060;GO:0023060;GO:0023060;GO:0023060 34171 1718.00 10.27 9.71 -0.0808929808990027 Down 0.14109760929864 grk gurken K02447|1|4e-139|494|dme:Dmel_CG17610|protein gruken precursor GO:0043231//intracellular membrane-bounded organelle GO:0005154//epidermal growth factor receptor binding GO:0007309//oocyte axis specification;GO:0003002//regionalization;GO:0040023//establishment of nucleus localization;GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0045165//cell fate commitment;GO:0007173//epidermal growth factor receptor signaling pathway 39435 2884.00 17.805 14.84 -0.26279134374226 Down 0.386970017170783 Tsf2 transferrin 2 K06569|1|5e-99|362|spu:581063|melanoma-associated antigen p97 - GO:0005506//iron ion binding GO:0030005;GO:0007043//cell-cell junction assembly;GO:0000041//transition metal ion transport 44482 242.00 40.145 89.73 1.16037009776708 Up 0.734282129177123 Met75Ca Met75Ca - - - - 246569 1302.04 0.535 1.34 1.32462220405663 Up 0.326641130630036 swif swift-tuttle, isoform B - - - - 40879 4124.86 5.765 6.465 0.165329762158483 Up 0.198982961299696 rn rotund, isoform G K09228|1|8e-41|169|mcc:720058|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0001654//eye development;GO:0010468//regulation of gene expression;GO:0006350;GO:0001654//eye development;GO:0010468//regulation of gene expression;GO:0006350;GO:0001654//eye development;GO:0010468//regulation of gene expression;GO:0006350 32732 3794.66 14.17 13.215 -0.100663333276449 Down 0.18524633469819 l(1)G0222 lethal (1) G0222, isoform G - - - - 32002 3050.83 17.555 17.63 0.00615047843942668 Up 0.0513802668075551 Rph rabphilin, isoform D K01104|1|3e-28|127|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K02677|3|9e-17|89.7|dya:Dyak_GE11833|classical protein kinase C [EC:2.7.11.13] GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle GO:0005083//small GTPase regulator activity;GO:0022892;GO:0046914//transition metal ion binding;GO:0005083//small GTPase regulator activity;GO:0022892;GO:0046914//transition metal ion binding GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport 35022 1041.00 0.585 0.78 0.415037499278844 Up 0.129210143970413 CG6012 CG6012 K10251|1|2e-41|169|mcc:714962|beta-keto reductase [EC:1.1.1.-];K10207|2|2e-39|162|ecb:100062795|testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64];K00100|5|2e-36|152|dme:Dmel_CG1444| [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0006909//phagocytosis 43130 3061.94 26.575 26.41 -0.0089853902513743 Down 0.0594703473781535 Lnk Lnk, isoform F K12459|1|2e-64|248|hsa:25970|SH2B adaptor protein 1/3 - GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding GO:0035468;GO:0035468;GO:0035468 2768931 5253.00 0.05 0.075 0.584962500721156 Up 0.0550785893541144 Muc30E mucin 30E - - - - 33684 2136.22 19.585 16.82 -0.219571422695602 Down 0.356855105005944 CG15626 tank, isoform B K10134|1|4e-61|236|nve:NEMVE_v1g97739|etoposide-induced 2.4 mRNA - - - 37164 1663.26 47.555 52.195 0.134314574937323 Up 0.295040285299168 CG42351 jabba, isoform I - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - - 40967 2774.49 43.16 47.305 0.132297815439997 Up 0.292002377493066 CG9636 CG9636, isoform D - - - - 3772662 738.94 10.195 15.545 0.608588841324468 Up 0.561352529388456 CG7215 CG7215, isoform B K02977|1|2e-07|55.5|cfa:474599|small subunit ribosomal protein S27Ae;K02927|2|2e-07|55.1|tad:TRIADDRAFT_33280|large subunit ribosomal protein L40e GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0006950//response to stress;GO:0019725//cellular homeostasis 42308 1060.00 0.295 0.165 -0.838248930003388 Down 0.115935807687228 CG5250 CG5250 K01540|1|1e-12|73.9|cqu:CpipJ_CPIJ007114|sodium/potassium-transporting ATPase subunit beta GO:0005887//integral to plasma membrane GO:0008556//potassium-transporting ATPase activity GO:0009206;GO:0030001//metal ion transport 31441 1448.00 5.665 6.265 0.145238553501345 Up 0.178708228767666 Cdk7 Cyclin-dependent kinase 7 K02202|1|0.0|705|dme:Dmel_CG3319|cyclin-dependent kinase 7 [EC:2.7.11.22] GO:0005626//insoluble fraction;GO:0005667//transcription factor complex;GO:0043232;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0035258//steroid hormone receptor binding;GO:0042623//ATPase activity, coupled GO:0006354//DNA-dependent transcription, elongation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006289//nucleotide-excision repair;GO:0051726//regulation of cell cycle;GO:0006464//cellular protein modification process;GO:0006352//DNA-dependent transcription, initiation;GO:0000087//M phase of mitotic cell cycle 38310 885.00 0.14 0.805 2.52356195605701 Up 0.32588165367851 CG16762 CG16762 - - - - 40514 2302.00 6.59 4.97 -0.407032613445765 Down 0.362897899881125 Mes2 Mesoderm-expressed 2, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0048513//organ development;GO:0007591//molting cycle, chitin-based cuticle;GO:0009792//embryo development ending in birth or egg hatching;GO:0002164//larval development;GO:0048513//organ development;GO:0007591//molting cycle, chitin-based cuticle;GO:0009792//embryo development ending in birth or egg hatching;GO:0002164//larval development 318260 1264.00 0.295 0.225 -0.390789953032167 Down 0.082089552238806 CG32939 CG32939 - - GO:0016407//acetyltransferase activity - 12798405 340.00 0.265 0.01 -4.7279204545632 Down 0.2511557257958 CG43112 CG43112 - - - - 31146 1704.00 12.295 13.42 0.126312936604101 Up 0.220017170783252 CG14805 CG14805 K02084|1|2e-11|70.9|bfo:BRAFLDRAFT_276588|apoptotic protease-activating factor;K03363|3|6e-10|65.9|der:Dere_GG25203|cell division cycle 20, cofactor of APC complex;K13124|5|1e-09|65.1|ame:551339|mitogen-activated protein kinase organizer 1 - - - 39792 1182.00 0.04 0.075 0.906890595608519 Up 0.0698718795403513 CG13045 CG13045 - - - - 5740165 865.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 CG34427 CG34427 - - GO:0030247//polysaccharide binding GO:0006022 38205 889.28 37.845 36.155 -0.0659075307747929 Down 0.177123233390569 CG7970 CG7970, isoform B K13347|1|2e-42|172|api:100168281|peroxisomal membrane protein 2 GO:0031224//intrinsic to membrane - - 326215 3288.23 5.51 5.93 0.105979785974846 Up 0.138389908862766 Smc5 Smc5, isoform H K06675|1|2e-14|82.0|phu:Phum_PHUM319270|structural maintenance of chromosome 4;K06636|2|5e-13|77.4|oaa:100081732|structural maintenance of chromosome 1 GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0032559;GO:0032559;GO:0032559 GO:0000819//sister chromatid segregation;GO:0000087//M phase of mitotic cell cycle;GO:0000819//sister chromatid segregation;GO:0000087//M phase of mitotic cell cycle;GO:0000819//sister chromatid segregation;GO:0000087//M phase of mitotic cell cycle 34932 1090.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG18518 CG18518 - - - - 19835272 7115.00 0.485 0.41 -0.242360837569044 Down 0.0744947827235504 37258 1071.00 0.435 0.205 -1.08539149123064 Down 0.163518689737155 CG15125 CG15125, isoform B - - - - 38915 1508.00 1.085 1.01 -0.103339749692685 Down 0.0668339717342491 CG7387 CG7387 K09504|1|1e-45|184|aag:AaeL_AAEL011055|DnaJ homolog subfamily A member 3;K09523|5|5e-45|182|dmo:Dmoj_GI19741|DnaJ homolog subfamily C member 3 - GO:0005515//protein binding;GO:0043169//cation binding GO:0044267//cellular protein metabolic process 34023 1707.06 173.485 137.425 -0.336166449357935 Down 0.559965658433496 CG5973 CG5973, isoform G K10693|1|1e-09|64.7|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K01104|2|5e-08|59.3|dya:Dyak_GE15440|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005501//retinoid binding;GO:0005501//retinoid binding;GO:0005501//retinoid binding;GO:0005501//retinoid binding GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 3355164 8235.31 56.345 69.985 0.312758147256935 Up 0.516609430722494 stnA stoned A, isoform F K03122|1|3e-50|202|gga:421307|transcription initiation factor TFIIA large subunit GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding;GO:0005488//binding GO:0008344//adult locomotory behavior;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0008344//adult locomotory behavior;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0015031//protein transport 3772559 3752.99 18.61 9.005 -1.04727987415288 Down 0.663551710474178 Skeletor skeletor, isoform E - GO:0015630//microtubule cytoskeleton;GO:0034399//nuclear periphery;GO:0005694//chromosome;GO:0015630//microtubule cytoskeleton;GO:0034399//nuclear periphery;GO:0005694//chromosome GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0006576//cellular biogenic amine metabolic process;GO:0007051//spindle organization;GO:0006547//histidine metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0007051//spindle organization;GO:0006547//histidine metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0006547//histidine metabolic process 34996 681.00 1131.065 1036.15 -0.126448968132248 Down 0.325518425571259 Cyt-c-p cytochrome c proximal, isoform B K08738|1|5e-59|227|dya:Dyak_GE12757|cytochrome c GO:0019866//organelle inner membrane;GO:0031980;GO:0044425//membrane part GO:0009055//electron carrier activity;GO:0005506//iron ion binding GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy 39961 5696.91 19.93 21.14 0.0850336665436252 Up 0.189208823140933 CycT cyclin T, isoform D - GO:0008023//transcription elongation factor complex;GO:0005700//polytene chromosome;GO:0008023//transcription elongation factor complex;GO:0005700//polytene chromosome GO:0004674//protein serine/threonine kinase activity;GO:0003711//transcription elongation regulator activity;GO:0019887//protein kinase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0003711//transcription elongation regulator activity;GO:0019887//protein kinase regulator activity GO:0065008;GO:0030036//actin cytoskeleton organization;GO:0010467//gene expression;GO:0006950//response to stress;GO:0065008;GO:0030036//actin cytoskeleton organization;GO:0010467//gene expression;GO:0006950//response to stress 31994 2914.00 0.1 0.055 -0.862496476250065 Down 0.0767071721040814 CG9806 CG9806 K11140|1|4e-147|522|der:Dere_GG12022|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 33578 2543.00 1.18 0.485 -1.28273020717471 Down 0.304517236824726 Spindly spindly K10352|1|4e-13|77.0|phu:Phum_PHUM344210|myosin heavy chain GO:0043229//intracellular organelle - GO:0009987//cellular process 35221 1604.00 24.445 22.275 -0.134113973598853 Down 0.264463082816008 Rab9 Rab9 K07976|1|6e-135|481|dme:Dmel_CG9994|Rab family, other;K07899|3|8e-58|224|spu:577515|Ras-related protein Rab-9A;K07900|5|2e-54|213|bfo:BRAFLDRAFT_121119|Ras-related protein Rab-9B - GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0016197//endosomal transport 42998 768.00 0.105 0.12 0.192645077942396 Up 0.0514463082816008 CG11786 CG11786 - - - - 35893 4050.84 21.465 19.46 -0.141474462666712 Down 0.269019944525162 CG8232 PAN2 ortholog, isoform B K01072|1|0.0|2403|dme:Dmel_CG8232|ubiquitin thiolesterase [EC:3.1.2.15];K12571|1|0.0|2403|dme:Dmel_CG8232|PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] GO:0044464//cell part GO:0005488//binding;GO:0004518//nuclease activity;GO:0016790//thiolester hydrolase activity GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0019941//modification-dependent protein catabolic process 39996 3553.00 12.965 12.02 -0.109185310142109 Down 0.191982565050852 Prestin prestin K04602|1|1e-84|314|gga:416011|cadherin EGF LAG seven-pass G-type receptor 3 (flamingo);K03321|2|1e-80|301|rno:64076|sulfate permease, SulP family;K13962|3|6e-61|235|mdo:100029542|solute carrier family 26 (sulfate anion transporter), member 7 GO:0031224//intrinsic to membrane GO:0015291//secondary active transmembrane transporter activity GO:0015698//inorganic anion transport 34884 2241.00 0.155 0.155 0 - 0.0382380134724607 vas vasa, isoform C K13982|1|0.0|1159|dya:Dyak_GE20836|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13] GO:0005737//cytoplasm;GO:0043232 GO:0004386//helicase activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003729//mRNA binding;GO:0032559;GO:0042623//ATPase activity, coupled GO:0007028//cytoplasm organization;GO:0008283//cell proliferation;GO:0051276//chromosome organization;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0006403//RNA localization;GO:0007309//oocyte axis specification;GO:0001709//cell fate determination 35780 3389.33 15.98 15.28 -0.0646228648922281 Down 0.137597411174217 Cul-4 cullin 4, isoform B K10609|1|0.0|1571|dme:Dmel_CG8711|cullin 4 GO:0000151//ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity;GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity GO:0042993//positive regulation of transcription factor import into nucleus;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination 3772248 595.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 His2B:CG33898 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 39803 572.00 9.715 5.915 -0.715835827245556 Down 0.535827499669793 CG13059 CG13059 - - - - 42279 1328.25 19.435 15.845 -0.294629447956964 Down 0.42365605600317 CG6005 CG6005, isoform B - - - - 43496 500.00 7.74 0.995 -2.95956513560076 Down 0.710044908202351 Obp99d Odorant-binding protein 99d - - GO:0005488//binding GO:0051234//establishment of localization;GO:0048102//autophagic cell death;GO:0002118//aggressive behavior 50356 13309.58 6.65 7.31 0.136517065563885 Up 0.182736758684454 CG34401 CG34401, isoform B - - GO:0046914//transition metal ion binding - 36863 1549.00 0.155 0.18 0.215728691055437 Up 0.0521727644961036 Amyrel amyrel K01176|1|0.0|1043|dme:Dmel_CG8221|alpha-amylase [EC:3.2.1.1] - - - 33814 2215.00 2.52 2.05 -0.297799823994471 Down 0.189472989037115 CG8965 rau, isoform B - - - GO:0023060 32574 6774.88 27.835 33.295 0.258405456951324 Up 0.434057588165368 Tob Tob, isoform F - - - - 53585 1724.00 19.41 17.45 -0.153573081616649 Down 0.276680755514463 debcl death executioner Bcl-2 homologue K02561|1|6e-22|105|oaa:100080424|BCL2-related ovarian killer protein GO:0031966//mitochondrial membrane - GO:0007006//mitochondrial membrane organization;GO:0008629;GO:0043066//negative regulation of apoptotic process 3772007 1295.47 17.48 18.4 0.0740005814437771 Up 0.156089023907014 Rpp20 Rpp20, isoform B K01164|1|6e-20|98.6|oaa:100088536|ribonuclease P [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle;GO:0030677//ribonuclease P complex GO:0005488//binding;GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process 3772367 829.00 18.215 17.59 -0.0503715122708211 Down 0.123068286884163 mRpL53 mitochondrial ribosomal protein L53 - - - - 12797900 701.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 318908 555.00 24.975 25.175 0.0115071002143664 Up 0.0608572183331132 Apf diadenosine tetraphosphate hydrolase K01518|1|4e-81|300|dme:Dmel_CG31713|bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] - GO:0004551//nucleotide diphosphatase activity - 39603 584.00 1.395 0.775 -0.84799690655495 Down 0.265486725663717 CG13473 CG13473 K03671|1|2e-62|237|dya:Dyak_GE22025|thioredoxin 1 - - GO:0008152//metabolic process;GO:0019725//cellular homeostasis 35453 615.39 1355.12 1148.405 -0.238789095301986 Down 0.478173292827896 RpL21 ribosomal protein L21, isoform C K02889|1|8e-89|325|dsi:Dsim_GD24352|large subunit ribosomal protein L21e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 32007 1639.65 2823.415 3071.78 0.12163369527405 Up 0.30630035662396 sesB stress-sensitive B, isoform E K05863|1|4e-164|578|dsi:Dsim_GD16013|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part GO:0015300;GO:0015300;GO:0015300;GO:0015300 GO:0016192//vesicle-mediated transport;GO:0015868//purine ribonucleotide transport;GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0010259//multicellular organismal aging;GO:0042391//regulation of membrane potential;GO:0009605//response to external stimulus;GO:0016192//vesicle-mediated transport;GO:0015868//purine ribonucleotide transport;GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0010259//multicellular organismal aging;GO:0042391//regulation of membrane potential;GO:0009605//response to external stimulus;GO:0016192//vesicle-mediated transport;GO:0015868//purine ribonucleotide transport;GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0010259//multicellular organismal aging;GO:0042391//regulation of membrane potential;GO:0009605//response to external stimulus;GO:0016192//vesicle-mediated transport;GO:0015868//purine ribonucleotide transport;GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0010259//multicellular organismal aging;GO:0042391//regulation of membrane potential;GO:0009605//response to external stimulus 5740829 135.00 0.01 0.585 5.8703647195834 Up 0.388852199181086 32500 735.00 0.22 0.245 0.155278225477911 Up 0.0554418174613657 CG8119 CG8119 K09427|1|6e-06|50.8|dpo:Dpse_GA13983|Adh transcription factor 1 - GO:0003676//nucleic acid binding - 39819 1357.79 23.25 20.375 -0.190430656876954 Down 0.338363492273148 CG4753 CG4753, isoform C K13523|1|0.0|750|dme:Dmel_CG4753|lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 44381 761.00 1.09 1.385 0.345557841272262 Up 0.151961431779157 Tim17b2 translocase inner membrane 17, isoform C K10836|1|1e-90|332|dme:Dmel_CG15257|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic to membrane GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting 32948 3938.17 40.385 51.385 0.347527738608387 Up 0.534209483555673 Tao Tao, isoform J K04429|1|0.0|937|dme:Dmel_CG14217|thousand and one amino acid protein kinase [EC:2.7.11.1] - GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0012501//programmed cell death;GO:0006464//cellular protein modification process;GO:0012501//programmed cell death;GO:0006464//cellular protein modification process;GO:0012501//programmed cell death;GO:0006464//cellular protein modification process;GO:0012501//programmed cell death;GO:0006464//cellular protein modification process;GO:0012501//programmed cell death;GO:0006464//cellular protein modification process;GO:0012501//programmed cell death 31572 2018.00 6.545 7.02 0.10107783835932 Up 0.141493858142914 CG12219 CG12219 K02215|1|1e-09|65.5|dme:Dmel_CG11924|chorion factor 2 - - - 19836181 735.56 0.11 0.27 1.29545588352617 Up 0.139050323603223 - CG43998, isoform D - - - - 39265 2613.19 17.57 16.48 -0.0923979488251578 Down 0.184024567428345 Plod procollagen lysyl hydroxylase, isoform B K13647|1|0.0|1462|dme:Dmel_CG6199|procollagen-lysine,2-oxoglutarate 5-dioxygenase, invertebrate [EC:1.14.11.4] - GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0019842//vitamin binding GO:0008152//metabolic process;GO:0008152//metabolic process 38917 1225.93 4.98 5.82 0.224873410840203 Up 0.231871615374455 CG8005 CG8005, isoform B K00809|1|0.0|728|dme:Dmel_CG8005|deoxyhypusine synthase [EC:2.5.1.46] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0046203//spermidine catabolic process;GO:0018205//peptidyl-lysine modification 32941 3191.04 20.435 21.86 0.0972511576512459 Up 0.208228767666094 CoRest CoRest, isoform K K11829|1|1e-54|216|gga:428911|REST corepressor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent 34999 787.80 123.47 65.43 -0.916136371188899 Down 0.716913221503104 CG17331 proteasome beta4 subunit, isoform B K02734|1|7e-112|402|dme:Dmel_CG17331|20S proteasome subunit beta 4 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0006508//proteolysis 35179 1371.00 4.355 3.285 -0.406779348276535 Down 0.302734117025492 CG10495 CG10495 K05545|1|0.0|767|dme:Dmel_CG10495|tRNA-dihydrouridine synthase 4 [EC:1.-.-.-] - GO:0030554//adenyl nucleotide binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0006399//tRNA metabolic process 45931 4154.43 48.59 56.23 0.210680614423518 Up 0.407277770439836 spir spire, isoform J K02098|1|0.0|1687|dme:Dmel_CG10076|spire GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0015631//tubulin binding GO:0006810//transport;GO:0007015//actin filament organization;GO:0051276//chromosome organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0006810//transport;GO:0007015//actin filament organization;GO:0051276//chromosome organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0006810//transport;GO:0007015//actin filament organization;GO:0051276//chromosome organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0006810//transport;GO:0007015//actin filament organization;GO:0051276//chromosome organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation;GO:0006810//transport;GO:0007015//actin filament organization;GO:0051276//chromosome organization;GO:0019094//pole plasm mRNA localization;GO:0030703//eggshell formation 246634 839.00 0.285 0.315 0.144389909335175 Up 0.0546823405098402 CG30472 CG30472 - - - - 37614 6856.07 15.085 17.665 0.22777905274395 Up 0.356293752476555 CG42260 CG42260, isoform D K05326|1|0.0|1436|dpo:Dpse_GA17508|cyclic nucleotide gated channel, invertebrate;K04950|3|7e-125|448|tgu:100222773|cyclic nucleotide gated channel alpha 3 - - - 19835324 1983.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 42581 2843.00 2.365 1.585 -0.577357343199988 Down 0.277869502047286 CG6678 CG6678 K10614|1|3e-22|107|gga:422514|E3 ubiquitin-protein ligase HERC3 [EC:6.3.2.19] - - - 35572 1465.00 2.135 2.68 0.327996930837282 Up 0.20829480914014 CG15909 CG15909 - - - - 5740700 1993.53 11.495 13.33 0.213670314370793 Up 0.311022322018227 CG34388 natalisin, isoform D - - - - 43843 2324.00 3.145 3.165 0.00914548254905215 Up 0.0432901862369568 fd102C forkhead domain 102C K09411|1|1e-26|121|tca:654864|forkhead box protein, other;K09396|2|9e-26|119|hmg:100202271|forkhead box protein C;K09399|3|1e-25|118|ptr:468057|forkhead box protein F - - - 35062 3513.00 0.24 0.37 0.624490864907794 Up 0.110454365341434 CG15143 CG15143 - - - - 40007 986.00 0.595 0.15 -1.98792716769943 Down 0.254655923920222 CG7330 CG7330, isoform B - - - - 42181 2132.61 7.3 7 -0.0605415419350507 Down 0.101802932241448 CG7183 CG7183, isoform B - - - - 31688 1764.00 0.455 0.765 0.749593202493956 Up 0.180359265618809 CG10920 CG10920 - - - - 33725 960.00 72.14 65.515 -0.138974166123025 Down 0.318022718267072 CG3887 CG3887, isoform C - - GO:0005488//binding GO:0019725//cellular homeostasis 33769 2926.00 0.985 0.75 -0.393233128960495 Down 0.13971073834368 H15 H15, isoform B K10185|1|2e-67|257|gga:373943|T-box protein 20 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007447//imaginal disc pattern formation;GO:0045595//regulation of cell differentiation;GO:0001709//cell fate determination;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:2000026//regulation of multicellular organismal development;GO:0010468//regulation of gene expression;GO:0014016//neuroblast differentiation;GO:0006935//chemotaxis;GO:0010002//cardioblast differentiation;GO:0006351//transcription, DNA-dependent;GO:0001708//cell fate specification;GO:0009790//embryo development 36445 3235.00 3.12 3.955 0.342131665610543 Up 0.261623299432043 Nrk neurospecific receptor kinase K05129|1|0.0|1486|dme:Dmel_CG4007|muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1] GO:0016020//membrane GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0023060 38966 7943.95 3.015 2.5 -0.270229907237998 Down 0.189803196407344 CG43163 CG43163, isoform D K09553|1|1e-21|107|api:100167947|stress-induced-phosphoprotein 1 - - - 14462839 853.00 0.14 0.055 -1.34792330342031 Down 0.104741777836481 35149 6146.00 7.29 7.235 -0.0109257977952126 Down 0.0502575617487782 ssp3 short spindle 3, isoform B - GO:0015630//microtubule cytoskeleton - GO:0007052//mitotic spindle organization 14462673 874.00 0.82 1.045 0.349807127462799 Up 0.131422533350944 CG43750 CG43750, isoform B - - - - 46813 600.00 93.205 57.63 -0.693587330881535 Down 0.676264694227975 CG6421 CG6421 - - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds - 8674081 2164.00 99.045 73.06 -0.439002392971851 Down 0.605567296262053 CG33655 CG33655, isoform C - - - - 42859 2129.00 22.92 17.8 -0.364729802903145 Down 0.491348566900013 CG13607 CG13607, isoform C - - GO:0032559;GO:0032559 - 33597 2669.65 17.385 17.68 0.0242752076638038 Up 0.0765090476819443 CG2818 CG2818, isoform B - - GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity GO:0023033;GO:0019400;GO:0023033;GO:0019400 50082 543.00 5.83 10.77 0.885450461343711 Up 0.586712455422005 CG3348 CG3348 - - GO:0030247//polysaccharide binding GO:0006022 35292 1073.00 136.755 66.57 -1.03864950804644 Down 0.731871615374455 pr purple K01737|1|2e-95|349|dse:Dsec_GM16965|6-pyruvoyl tetrahydrobiopterin synthase [EC:4.2.3.12] - GO:0016838//carbon-oxygen lyase activity, acting on phosphates;GO:0043169//cation binding GO:0042559//pteridine-containing compound biosynthetic process 38443 1572.00 7.56 6.56 -0.204690419602989 Down 0.243263769647339 ntc nutcracker - - - - 32395 641.00 40.905 44.27 0.114052172461446 Up 0.25614185708625 mRpS25 mitochondrial ribosomal protein S25 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 37089 3551.00 6.065 3.91 -0.633339037813158 Down 0.43917580240391 fj four-jointed - - - - 43541 695.00 59.36 95.09 0.679802538202025 Up 0.674514595165764 capa capability - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0042044//fluid transport;GO:0006811//ion transport 19835639 1320.00 6.3 7.155 0.183599938339389 Up 0.220215295205389 14462811 1650.00 18.72 19.92 0.0896372124846767 Up 0.188812574296658 41721 3787.91 14.515 12.62 -0.201832661644113 Down 0.309404305904108 RpII140 RNA polymerase II 140kD subunit, isoform B K03010|1|0.0|2319|dse:Dsec_GM24152|DNA-directed RNA polymerase II subunit B [EC:2.7.7.6] - - - 3885637 1829.22 5.75 7.015 0.286881147788162 Up 0.302370888918241 CG33993 CG33993, isoform B K07293|1|8e-07|55.1|dsi:Dsim_GD24731|protein tyrosine phosphatase, non-receptor type 11 [EC:3.1.3.48] - GO:0005488//binding;GO:0005488//binding - 19834967 601.00 0.07 0.08 0.192645077942396 Up 0.045898824461762 33198 1299.43 130.365 135.21 0.052645264723799 Up 0.156518293488311 CG3625 CG3625, isoform E - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 33341 1030.00 3.28 5.005 0.60967425421791 Up 0.401829348831066 CG14352 CG14352 - - - - 34107 2892.29 17.53 17.21 -0.0265788987193345 Down 0.0879672434288733 CG8668 CG8668, isoform B K07819|1|1e-98|361|dpe:Dper_GL24766|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process 37453 2156.10 17.34 17.325 -0.00124854619725902 Down 0.0416061286487914 CG10494 CG10494, isoform B - - - - 59178 1112.89 318.245 224.485 -0.503518800015539 Down 0.644498745211993 Tsp42Ea tetraspanin 42Ea, isoform C K06497|1|1e-125|449|dme:Dmel_CG18817|CD63 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 19835092 981.00 0.045 0.1 1.15200309344505 Up 0.0796790384361379 3355116 7096.00 1.065 1.22 0.196027717337048 Up 0.0996565843349624 Cht3 chitinase 3, isoform C K01183|1|0.0|4606|dme:Dmel_CG18140|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding GO:0006026 32824 1424.00 0.06 0.24 2 Up 0.157376832650905 CG15056 CG15056 K13125|1|5e-145|514|dsi:Dsim_GD17393|nitric oxide synthase-interacting protein - - - 41358 873.00 5.585 3.51 -0.670086250178754 Down 0.436666226390173 scpr-A SCP-containing protein A K00747|1|3e-08|58.9|tca:656110|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] - - - 326153 5402.49 10.755 12.39 0.204168662717541 Up 0.294644036454894 tho2 tho2, isoform C K12879|1|0.0|2776|dme:Dmel_CG31671|THO complex subunit 2 - - - 37542 3008.00 16.07 17.92 0.15720070838251 Up 0.280246995112931 ari-2 ariadne 2 K11969|1|0.0|943|dsi:Dsim_GD11654|ariadne-2 - GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding - 34786 1456.00 199.375 179.35 -0.15270677358207 Down 0.350482102760534 CAH1 carbonic anhydrase 1 K01672|1|6e-163|573|dme:Dmel_CG7820|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 31072 2890.00 1.295 1.5 0.212010402809327 Up 0.113228107251354 CG11403 CG11403 K11273|1|0.0|1561|dme:Dmel_CG11403|chromosome transmission fidelity protein 1 [EC:3.6.1.-] - - - 34111 491.00 60.115 55.045 -0.127113496780481 Down 0.297516840575882 CG8498 CG8498, isoform B K08762|1|1e-41|168|dpo:Dpse_GA21120|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) - GO:0005504//fatty acid binding GO:0055082//cellular chemical homeostasis 39318 1881.00 0.205 0.225 0.134301091711591 Up 0.0491348566900013 CG6053 CG6053, isoform C K11143|1|0.0|1142|dme:Dmel_CG6053|dynein intermediate chain 2, axonemal - - - 19835507 501.00 0.17 0.46 1.43609911480667 Up 0.19439307885352 19835630 2633.00 0.115 0.045 -1.3536369546147 Down 0.0929203539823009 38651 1604.00 12.725 12.48 -0.0280477221008092 Down 0.0799762250693435 Cralbp cellular retinaldehyde binding protein K10693|1|2e-07|57.0|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K01104|2|3e-07|56.2|dre:560176|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part - GO:0051234//establishment of localization 42489 810.00 2.24 1.45 -0.62744583204267 Down 0.282393343019416 CG17279 CG17279, isoform C K12347|1|4e-07|55.1|dan:Dana_GF18523|natural resistance-associated macrophage protein - - - 35634 1752.00 12.125 14.84 0.291506344658951 Up 0.395786553955884 Cyp9b1 cytochrome P450-9b1 K00517|1|0.0|811|dme:Dmel_CG4486| [EC:1.14.-.-];K07424|3|4e-125|448|dmo:Dmoj_GI24725|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 42608 5047.00 0.505 0.63 0.319068440748122 Up 0.102628450667019 CG34377 CG34377, isoform D K01106|1|3e-07|56.2|dre:325179|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] - - - 37852 1687.79 43.525 48.07 0.143292505599432 Up 0.30791837273808 CG3209 CG3209, isoform E K13506|1|0.0|826|dme:Dmel_CG3209|glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0008415;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups GO:0044255//cellular lipid metabolic process 33405 1351.05 43.52 15.675 -1.47321311356094 Down 0.739367322678642 CG4267 CG4267, isoform B K01059|1|4e-38|159|dme:Dmel_CG4582|lipoprotein lipase [EC:3.1.1.34];K01046|3|6e-34|145|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|3|6e-34|145|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 8674066 5088.79 97.42 150.335 0.625891038781625 Up 0.672467309470347 CG42492 CG42492, isoform G - - - - 318175 317.00 49.74 62.255 0.323783204092118 Up 0.52166160348699 CG32726 CG32726, isoform B - - - - 39778 1138.00 2.98 2.28 -0.38627850629742 Down 0.245443138290847 l(3)72Dr lethal (3) 72Dr K01307|1|4e-63|241|aga:AgaP_AGAP006670|gamma-glutamyl hydrolase [EC:3.4.19.9] - GO:0008238//exopeptidase activity GO:0009064//glutamine family amino acid metabolic process 8674044 993.00 71.515 83.07 0.21608168098314 Up 0.430689472989037 CG42596 CG42596 K06774|1|7e-08|57.8|rno:50864|neurotrimin - - - 39673 453.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 Z600 Z600 - GO:0044424//intracellular part - GO:0007088//regulation of mitosis;GO:0010004//gastrulation involving germ band extension 41200 517.65 1061.18 1008.295 -0.0737515961771079 Down 0.205686170915335 RpS29 ribosomal protein S29, isoform B K02980|1|1e-29|129|dya:Dyak_GE25988|small subunit ribosomal protein S29e GO:0030529//ribonucleoprotein complex GO:0043169//cation binding;GO:0005198//structural molecule activity GO:0048468//cell development;GO:0010467//gene expression 34528 1210.00 3.835 3.625 -0.0812455826006366 Down 0.0920618148197068 Art8 arginine methyltransferase 8 K11437|1|8e-51|201|dre:448867|protein arginine N-methyltransferase 6 [EC:2.1.1.-];K11435|2|2e-49|196|rno:499420|protein arginine N-methyltransferase 2 [EC:2.1.1.-] GO:0044424//intracellular part GO:0008168//methyltransferase activity - 12797864 1392.00 4.39 2.055 -1.09508254585368 Down 0.495641262712984 19835978 931.00 0.175 0.98 2.48542682717024 Up 0.357053229428081 12798573 1239.00 0.19 0.38 1 Up 0.14816404702153 40647 2381.42 13.595 13.065 -0.057369026704739 Down 0.126007132479197 CG1172 CG1172, isoform C - - - - 37931 557.79 725.745 682.83 -0.087936283201544 Down 0.246004490820235 CG4692 CG4692, isoform B K02130|1|3e-62|237|dme:Dmel_CG4692|F-type H+-transporting ATPase subunit f [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005753//mitochondrial proton-transporting ATP synthase complex - GO:0006818//hydrogen transport;GO:0006818//hydrogen transport 39986 1288.00 52.94 47.895 -0.144483141204149 Down 0.311319508651433 CG5567 CG5567 K01101|1|0.0|664|dme:Dmel_CG5567|4-nitrophenyl phosphatase [EC:3.1.3.41] - GO:0042578//phosphoric ester hydrolase activity - 32430 3244.04 11.77 10.645 -0.14493837058615 Down 0.226324131554616 be ben, isoform F - - - - 19835580 707.00 0.86 0.785 -0.131644005810471 Down 0.0682208426892088 33559 1338.00 1.15 1.44 0.324434950497937 Up 0.150046229031832 CG2772 CG2772 K01046|1|5e-71|268|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|3|1e-59|230|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - - GO:0044238//primary metabolic process 32713 1439.77 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 CG10598 CG10598, isoform C - - - - 34721 911.00 3.935 3.62 -0.120373938424281 Down 0.122473913617752 Ski6 Ski6, isoform B K11600|1|4e-136|483|dme:Dmel_CG15481|exosome complex component RRP41 GO:0005694//chromosome;GO:0000178//exosome (RNase complex);GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0016779//nucleotidyltransferase activity GO:0010467//gene expression 35544 631.00 871.615 1605.77 0.881502335700356 Up 0.725399550917976 CG8343 CG8343 K06560|1|1e-09|62.8|cin:100176419|mannose receptor, C type - GO:0030246//carbohydrate binding - 44000 6098.37 19.925 20.185 0.018703862602676 Up 0.0738343679830934 Spt6 Spt6, isoform B K11292|1|0.0|2920|dme:Dmel_CG12225|transcription elongation factor SPT6 GO:0000178//exosome (RNase complex);GO:0005700//polytene chromosome GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0016787//hydrolase activity GO:0006259//DNA metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0033554//cellular response to stress 34706 2364.00 0.905 0.875 -0.0486347752508766 Down 0.0483423590014529 CG5204 CG5204 K00383|1|9e-19|95.9|spu:589396|glutathione reductase (NADPH) [EC:1.8.1.7];K09228|4|1e-16|89.0|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 318093 1034.00 0.08 0.185 1.20945336562895 Up 0.108142913749835 TwdlY TweedleY - - - - 14462471 744.00 0.06 0.125 1.05889368905357 Up 0.0856557918372738 8674037 2158.00 4.415 5.06 0.196723947045844 Up 0.199511293092062 CG42488 CG42488 - - - - 33795 2881.00 16.62 19.055 0.197249226041824 Up 0.3329480914014 CG31646 CG31646 K06774|1|1e-34|149|mdo:100017555|neurotrimin;K06773|5|2e-33|145|tgu:100229124|opioid binding protein/cell adhesion molecule-like - - - 36290 2153.00 18.95 19.07 0.00910699525430222 Up 0.0563994188350284 Drep-1 DNA fragmentation factor-related protein 1, isoform B K02310|1|3e-07|57.4|nve:NEMVE_v1g129698|DNA fragmentation factor, 45 kD, alpha subunit GO:0044464//cell part GO:0005488//binding GO:0000737//DNA catabolic process, endonucleolytic;GO:0043066//negative regulation of apoptotic process 34638 886.00 1.27 1.48 0.220768678856784 Up 0.114416853784176 Phae2 phaedra 2, isoform C K01312|1|5e-35|147|bfo:BRAFLDRAFT_88359|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40782 1409.00 4.63 4.29 -0.110034545760691 Down 0.125148593316603 CG18048 CG18048 - - GO:0016741 - 19835136 1050.00 0.775 0.415 -0.901084973927313 Down 0.202747325320301 - CG45066 - - - - 37064 4100.00 0.175 0.13 -0.428843298803874 Down 0.0678576145819575 CG5756 CG5756, isoform C - - - - 37417 8829.89 51.52 52.33 0.0225056655000979 Up 0.0872738079513935 tud tudor, isoform B - - - - 42322 2517.48 13.55 16.935 0.321715135252923 Up 0.434817065116893 CG5316 CG5316, isoform D K10863|1|3e-60|231|dme:Dmel_CG5316|aprataxin [EC:3.-.-.-] GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0003677//DNA binding GO:0000377;GO:0006281//DNA repair;GO:0000377;GO:0006281//DNA repair;GO:0000377;GO:0006281//DNA repair 34325 2250.40 34.27 35.01 0.03082086990933 Up 0.102892616563202 CG4658 CG4658, isoform E - - - - 35748 1935.00 21.27 23.61 0.15057800826797 Up 0.288898428212918 CG8728 CG8728 K01412|1|0.0|990|dme:Dmel_CG8728|mitochondrial processing peptidase [EC:3.4.24.64] GO:0031980 GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0044281//small molecule metabolic process;GO:0051604//protein maturation 34245 1298.00 0.7 0.485 -0.529370174757839 Down 0.137135120855897 borr borealin-related, isoform B K11514|1|1e-15|84.3|aag:AaeL_AAEL011330|Borealin GO:0005875//microtubule associated complex;GO:0044427//chromosomal part;GO:0044444//cytoplasmic part;GO:0005875//microtubule associated complex;GO:0044427//chromosomal part;GO:0044444//cytoplasmic part - GO:0006468//protein phosphorylation;GO:0051301//cell division;GO:0048513//organ development;GO:0007067//mitosis;GO:0033036;GO:0006468//protein phosphorylation;GO:0048513//organ development;GO:0007067//mitosis;GO:0033036;GO:0033206//cytokinesis after meiosis;GO:0007140//male meiosis 32357 1270.00 0.875 1.68 0.941106310946432 Up 0.309272222956016 CG11068 CG11068 - - - - 33760 2610.54 20.025 21.035 0.070989575472717 Up 0.160282657508916 CG14024 CG14024, isoform B K01017|1|4e-29|129|oaa:100076609|chondroitin 4-sulfotransferase 11 [EC:2.8.2.5] GO:0031224//intrinsic to membrane GO:0016782//transferase activity, transferring sulfur-containing groups GO:0005975//carbohydrate metabolic process 42186 2196.06 363.035 405.39 0.159201857070693 Up 0.370426627922335 14-3-3epsilon 14-3-3epsilon, isoform D K06630|1|3e-142|504|dya:Dyak_GE25525|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein - - - 14462401 881.00 0.71 1.635 1.2033997059934 Up 0.341104213446044 CG43673 CG43673 - - - - 37590 1798.31 4.92 11.83 1.26571985300055 Up 0.649154669132215 Ugt58Fa Ugt58Fa, isoform B K00699|1|0.0|984|dme:Dmel_CG4414|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 35796 2071.00 1.56 1.435 -0.120495292186561 Down 0.0806696605468234 Mlh1 Mlh1, isoform B K08734|1|0.0|1249|dme:Dmel_CG11482|DNA mismatch repair protein MLH1 GO:0032300//mismatch repair complex;GO:0000794//condensed nuclear chromosome GO:0003690//double-stranded DNA binding;GO:0032559 GO:0006281//DNA repair 41156 681.00 92.155 66.295 -0.475162377737494 Down 0.619700171707833 CG9396 CG9396 - - - - 3772614 1031.00 12.075 17.32 0.520415741003589 Up 0.541969356756043 31740 1699.00 20.42 19.32 -0.0798877720420284 Down 0.174712719587901 CG2263 CG2263 K01889|1|0.0|932|dme:Dmel_CG2263|phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0003723//RNA binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 10178832 2084.00 0.795 1.315 0.726036034007947 Up 0.235437854972923 pre-mod(mdg4)-W pre-mod(mdg4)-W - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 42643 893.00 24.925 52.145 1.06493541981801 Up 0.71374323074891 CG7054 CG7054 - - - - 32627 4020.00 11.115 11.525 0.0522588022897102 Up 0.109166556597543 Cap Chromosome-associated protein K06669|1|0.0|2263|dme:Dmel_CG9802|structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0043232 GO:0032559 GO:0007059//chromosome segregation;GO:0006996//organelle organization 40013 1937.97 0.705 0.285 -1.30666133823405 Down 0.234843481706512 CG13700 CG13700, isoform E - - - - 31726 1404.00 225.485 186.705 -0.272270900113512 Down 0.500561352529388 CG2254 CG2254 K11151|1|5e-37|155|cfa:486998|retinol dehydrogenase 10 [EC:1.1.1.-] - - - 19836219 481.00 4.165 2.675 -0.638777604077039 Down 0.380960243032624 38002 2550.42 103.5 85.43 -0.276816080225407 Down 0.498712191256109 uzip unzipped, isoform B - GO:0031224//intrinsic to membrane - GO:0048667//cell morphogenesis involved in neuron differentiation 19835530 501.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 37075 2054.00 3.19 4.55 0.512310121321189 Up 0.352364284770836 CG10914 CG10914 - - - - 37597 2577.00 0.11 0.055 -1 Down 0.0856557918372738 CG13511 CG13511, isoform B - - - - 19834897 1157.00 0.04 0.305 2.93073733756289 Up 0.204794611015718 38329 1077.40 20.89 18.945 -0.1409953525584 Down 0.267434949148065 CG1143 CG1143, isoform B - - - - 32803 4561.43 12.215 11.8 -0.0498670040180526 Down 0.109166556597543 CG33639 CG33639, isoform D K04282|1|7e-06|53.1|dre:569382|thyrotropin-releasing hormone receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 19835858 1844.00 0.08 0.075 -0.0931094043914813 Down 0.0382380134724607 33474 2742.93 15.9 20.9 0.394476176796527 Up 0.501122705058777 daw dawdle, isoform C K04669|1|0.0|1000|dme:Dmel_CG16987|TGF-beta receptor, other - GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0006935//chemotaxis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006935//chemotaxis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 40816 693.00 8.1 9.93 0.293871809756387 Up 0.348665962224277 agt O-6-alkylguanine-DNA alkyltransferase K00567|1|7e-97|352|dme:Dmel_CG1303|methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0008172 GO:0006281//DNA repair 246611 880.00 0.36 0.3 -0.263034405833794 Down 0.0724144762911108 CG30432 CG30432 - - - - 36418 1009.86 3.285 4.12 0.326750966860889 Up 0.260071324791969 CG3814 CG3814, isoform D K06890|1|1e-127|456|dya:Dyak_GE13413| GO:0008328//ionotropic glutamate receptor complex;GO:0008328//ionotropic glutamate receptor complex - - 19836175 434.86 123.73 128.41 0.053562213998052 Up 0.156254127592128 - CG44242, isoform B K10105|1|3e-11|67.0|dme:Dmel_CG8446|lipoyltransferase 1 [EC:6.-.-.-] - - GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 41318 1181.88 36.46 26.955 -0.435761651808036 Down 0.567560427948752 Adk3 adenylate kinase-3, isoform D K00939|1|1e-121|435|dme:Dmel_CG6612|adenylate kinase [EC:2.7.4.3] GO:0031980;GO:0031980 GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0032559;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0032559 GO:0009180;GO:0009180 19835099 439.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 39104 1206.00 14.42 16.655 0.207884189433529 Up 0.330669660546823 pall pallbearer K10306|1|2e-159|561|dme:Dmel_CG3428|F-box protein 28 - - - 41468 1600.00 1.585 2.89 0.866586652361271 Up 0.380927222295602 CG14740 CG14740 K01647|1|0.0|920|dme:Dmel_CG14740|citrate synthase [EC:2.3.3.1] GO:0031980 GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0009060//aerobic respiration;GO:0005975//carbohydrate metabolic process;GO:0019752//carboxylic acid metabolic process 14462843 193.00 0.52 0.94 0.854149133536545 Up 0.216450931184784 CG43965 CG43965 - - - - 49090 15873.76 15.465 13.075 -0.242195886954961 Down 0.354048342359001 Rya-r44F ryanodine receptor, isoform J K05327|1|0.0|9409|dme:Dmel_CG10844|ryanodine receptor, invertebrate GO:0031224//intrinsic to membrane;GO:0015630//microtubule cytoskeleton;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0015630//microtubule cytoskeleton;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0015630//microtubule cytoskeleton;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0015630//microtubule cytoskeleton;GO:0031090//organelle membrane GO:0005218//intracellular ligand-gated calcium channel activity;GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0004871//signal transducer activity;GO:0046872//metal ion binding GO:0003012//muscle system process;GO:0006875//cellular metal ion homeostasis;GO:0070838//divalent metal ion transport;GO:0003012//muscle system process;GO:0006875//cellular metal ion homeostasis;GO:0070838//divalent metal ion transport;GO:0003012//muscle system process;GO:0006875//cellular metal ion homeostasis;GO:0070838//divalent metal ion transport;GO:0003012//muscle system process;GO:0006875//cellular metal ion homeostasis;GO:0070838//divalent metal ion transport 32494 1945.00 5.15 4.795 -0.10304161705245 Down 0.12534671773874 CG9215 CG9215 K09228|1|1e-37|158|api:100159445|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding - 40362 5407.00 1.585 3.27 1.04480779535868 Up 0.43640206049399 CG32436 CG32436 - - - - 37330 2443.83 4.075 3.07 -0.408561403748261 Down 0.29401664245146 CG11180 CG11180, isoform B K11135|1|0.0|1105|dme:Dmel_CG11180|Pin2-interacting protein X1 - - - 31376 6998.42 170.62 246.325 0.529776288538523 Up 0.653018095363889 norpA no receptor potential A, isoform F K05858|1|0.0|1932|dwi:Dwil_GK15712|phospholipase C, beta [EC:3.1.4.11] GO:0005626//insoluble fraction;GO:0016028//rhabdomere;GO:0005626//insoluble fraction;GO:0016028//rhabdomere;GO:0005626//insoluble fraction;GO:0016028//rhabdomere;GO:0005626//insoluble fraction;GO:0016028//rhabdomere GO:0004629//phospholipase C activity;GO:0060089;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding GO:0007626//locomotory behavior;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0002251;GO:0009586;GO:0006650//glycerophospholipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0043954//cellular component maintenance;GO:0019932//second-messenger-mediated signaling;GO:0007606//sensory perception of chemical stimulus;GO:0007626//locomotory behavior;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0002251;GO:0009586;GO:0006650//glycerophospholipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0043954//cellular component maintenance;GO:0019932//second-messenger-mediated signaling;GO:0007606//sensory perception of chemical stimulus;GO:0007626//locomotory behavior;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0002251;GO:0009586;GO:0006650//glycerophospholipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0043954//cellular component maintenance;GO:0019932//second-messenger-mediated signaling;GO:0007606//sensory perception of chemical stimulus;GO:0007626//locomotory behavior;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0002251;GO:0009586;GO:0006650//glycerophospholipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0043954//cellular component maintenance;GO:0019932//second-messenger-mediated signaling;GO:0007606//sensory perception of chemical stimulus 317901 349.00 0.33 0.145 -1.18641312423088 Down 0.145654471007793 CG32188 CG32188 - - - - 39671 1234.00 9.41 11.1 0.238293048508932 Up 0.316305639941883 CG7857 CG7857 K13349|1|2e-64|142|dse:Dsec_GM24491|Mpv17-like protein;K13717|3|2e-06|53.5|spu:589808|OTU domain-containing protein 3 - - - 37576 1077.00 0.88 1.06 0.268488835925902 Up 0.11144498745212 CG3927 CG3927 K13198|1|5e-39|161|bta:538775|KH domain-containing, RNA-binding, signal transduction-associated protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0012501//programmed cell death 35287 2601.50 2.175 3.01 0.468748086023611 Up 0.27780346057324 barr barren, isoform C K06676|1|0.0|1344|dme:Dmel_CG10726|condensin complex subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome - GO:0007439//ectodermal digestive tract development;GO:0000070//mitotic sister chromatid segregation;GO:0048598//embryonic morphogenesis;GO:0060541//respiratory system development;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development;GO:0009060//aerobic respiration;GO:0007439//ectodermal digestive tract development;GO:0000070//mitotic sister chromatid segregation;GO:0048598//embryonic morphogenesis;GO:0060541//respiratory system development;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development;GO:0009060//aerobic respiration 42554 2511.00 6.72 6.04 -0.153912683453682 Down 0.189307885352001 CG31176 CG31176 - - - - 37560 732.83 15.535 13.7 -0.181346348273952 Down 0.294181746136574 Mes4 Mesoderm-expressed 4, isoform B K03506|1|2e-60|231|dme:Dmel_CG11301|DNA polymerase epsilon subunit 4 [EC:2.7.7.7] GO:0000109//nucleotide-excision repair complex;GO:0000109//nucleotide-excision repair complex GO:0003677//DNA binding;GO:0003677//DNA binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress 44307 2847.58 476.2 457.485 -0.0578431794637684 Down 0.183661339321094 Vha16-1 vacuolar H[+] ATPase 16kD subunit 1, isoform D K02155|1|3e-81|303|dya:Dyak_GE24687|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033176;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033176;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033176;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033176;GO:0031090//organelle membrane GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 41766 728.95 31.81 27.97 -0.185600118063322 Down 0.356194690265487 CG8066 CG8066, isoform B K01373|1|5e-07|55.5|dgr:Dgri_GH22731|cathepsin F [EC:3.4.22.41] - - - 31150 898.87 29.065 28.16 -0.0456355745945886 Down 0.133700964205521 mRpL16 mitochondrial ribosomal protein L16, isoform B - - - - 35262 12133.00 8.795 11.005 0.323403662419596 Up 0.384922731475367 CG10631 CG10631 K09228|1|2e-11|73.9|mmu:22718|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 36200 688.42 77.425 72.22 -0.100401057613385 Down 0.249405626733589 CG13220 CG13220, isoform B - - - - 326258 1025.00 0.865 2.73 1.65812891328313 Up 0.482994320433232 CG33109 CG33109 - - - - 50074 3104.00 3.57 1.86 -0.940621452921068 Down 0.431779157310791 CG13643 CG13643, isoform E - - GO:0030247//polysaccharide binding GO:0006022 40346 1104.00 105.925 119.055 0.168585082613951 Up 0.374554220050192 CG9391 CG9391, isoform C K01092|1|2e-158|558|dme:Dmel_CG9391|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] - GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process 42765 1836.00 0.06 0.075 0.321928094887363 Up 0.0540219257693832 Ir94e ionotropic receptor 94e - - - - 38455 1531.00 11.55 12.465 0.109990031188081 Up 0.189373926826047 CG14980 Ccz1 ortholog - - - - 41112 1811.54 12.65 14.56 0.202872970617024 Up 0.310394928014793 CG8866 CG8866, isoform B K08269|1|0.0|962|dsi:Dsim_GD20804|unc51-like kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 38386 423.00 0.41 0.01 -5.35755200461808 Down 0.323239994716682 CG14957 CG14957 - - GO:0030247//polysaccharide binding GO:0006022 19835456 1275.00 0.045 0.23 2.3536369546147 Up 0.161207238145555 3772218 1570.00 12.835 13.63 0.086702266229791 Up 0.1670519085986 CG33649 CG33649 K02333|1|0.0|666|dme:Dmel_CG33650|DNA polymerase gamma 2;K12385|2|2e-21|104|cqu:CpipJ_CPIJ004884|Niemann-Pick C1 protein GO:0005759//mitochondrial matrix GO:0034061;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006448//regulation of translational elongation;GO:0006261//DNA-dependent DNA replication;GO:0007005//mitochondrion organization;GO:0006418//tRNA aminoacylation for protein translation 33581 2611.00 1.19 0.935 -0.347923303420307 Down 0.143210936468102 sob sister of odd and bowl K09215|1|3e-170|599|dme:Dmel_CG3242|odd-skipped GO:0044464//cell part GO:0046914//transition metal ion binding GO:0006909//phagocytosis;GO:0007480//imaginal disc-derived leg morphogenesis 14462629 698.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 41536 1357.00 0.345 0.225 -0.616671360448494 Down 0.106524897635715 desat2 desaturase 2 K00507|1|0.0|765|dme:Dmel_CG5925|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] - - - 19836220 5117.35 13.645 11.52 -0.244231677831828 Down 0.341764628186501 - CG45092, isoform F - - - - 36761 5064.72 6.805 7.155 0.0723566052226729 Up 0.112072381455554 CG8370 CG8370, isoform B - - - - 38819 2944.00 40.215 52.705 0.390206113415373 Up 0.559338264430062 sec63 Sec63 ortholog K09540|1|0.0|1276|dme:Dmel_CG8583|translocation protein SEC63 GO:0030867//rough endoplasmic reticulum membrane GO:0005515//protein binding GO:0044267//cellular protein metabolic process 39598 964.00 2.53 3.34 0.400710717779742 Up 0.26436402060494 CG5048 CG5048 - - - - 37095 549.00 0.375 0.365 -0.0389941316158637 Down 0.0418702945449742 CG18538 CG18538 - - - - 42955 927.00 2.945 1.01 -1.54391234107867 Down 0.485272751287809 CG6980 CG6980 K09553|1|2e-12|72.8|phu:Phum_PHUM345830|stress-induced-phosphoprotein 1 - - - 4379863 495.00 36.055 39.8 0.142569088778285 Up 0.301677453440761 CG34150 CG34150 - - - - 39978 2203.00 63.295 58.57 -0.111929643751023 Down 0.2645951657641 NUCB1 NUCB1 - - GO:0046872//metal ion binding GO:0044238//primary metabolic process 41603 2378.89 30.125 30.88 0.0357115112633942 Up 0.117851010434553 CG12360 CG12360, isoform C - - - - 43040 1132.98 3.075 3.315 0.108422459885986 Up 0.104477611940299 CG11875 nucleoporin 37kD, isoform B K08518|1|5e-06|52.0|phu:Phum_PHUM212560|syntaxin binding protein 5 (tomosyn) - - - 31934 3680.03 0.08 0.07 -0.192645077942396 Down 0.045898824461762 CG2990 CG2990, isoform C K10742|1|0.0|2050|dme:Dmel_CG2990|DNA replication ATP-dependent helicase Dna2 [EC:3.6.1.-] - GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032559;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process 38472 1213.00 10.465 11.56 0.14356908624497 Up 0.224177783648131 Mul1 mitochondrial E3 ubiquitin protein ligase 1 homologue K10641|1|2e-07|57.4|nve:NEMVE_v1g241634|E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19];K04725|2|2e-07|57.4|bfo:BRAFLDRAFT_203130|baculoviral IAP repeat-containing 2/3/4 - GO:0046914//transition metal ion binding - 3885577 715.00 1.075 1.02 -0.0757675076179646 Down 0.0567956676793026 CG34008 CG34008 - - - - 8674095 309.00 1.715 2.1 0.292180751493311 Up 0.170056795667679 Sfp26Ac seminal fluid protein 26Ac - - - - 318046 2091.00 1.065 0.745 -0.515541099763677 Down 0.171047417778365 mthl14 methuselah-like 14 - GO:0044464//cell part - GO:0007166//cell surface receptor signaling pathway 36065 1490.00 0.23 0.63 1.4537179674429 Up 0.232664113063004 CG12917 CG12917 - - GO:0043169//cation binding;GO:0003824//catalytic activity - 39616 5991.00 65.535 56.405 -0.21644255105161 Down 0.423755118214239 CG17839 CG17839, isoform C K06255|1|1e-09|67.0|bta:444872|heparan sulfate proteoglycan 2 (perlecan);K06771|3|5e-09|64.7|hsa:4099|myelin associated glycoprotein;K06773|4|7e-09|64.3|tgu:100229124|opioid binding protein/cell adhesion molecule-like - - - 41302 6954.91 4.715 3.17 -0.572774930535689 Down 0.379375247655528 Cad86C cadherin 86C, isoform G K06813|1|8e-42|174|gga:423718|cadherin 23 GO:0031224//intrinsic to membrane GO:0046872//metal ion binding GO:0016337//cell-cell adhesion 53522 1039.00 6.23 3.72 -0.74392954191597 Down 0.478998811253467 lectin-46Cb lectin-46Cb K06560|1|4e-06|52.4|nve:NEMVE_v1g238062|mannose receptor, C type;K10061|2|5e-06|52.0|oaa:100081235|C-type lectin superfamily 4, member G - GO:0030246//carbohydrate binding GO:0045297//post-mating behavior;GO:0048609//multicellular organismal reproductive process 31080 1002.00 1.66 1.635 -0.0218926058488423 Down 0.046559239202219 Tsp2A tetraspanin 2A, isoform B K06460|1|4e-132|470|dpo:Dpse_GA10989|CD9 antigen;K06508|4|1e-16|86.7|bta:511435|CD81 antigen GO:0031224//intrinsic to membrane - - 37082 3491.00 12.26 11.76 -0.0600709188544171 Down 0.123695680887597 CG5726 CG5726 - - - - 39089 3121.65 9.63 9.465 -0.024933292139754 Down 0.0657773081495179 MTF-1 metal response element-binding transcription Factor-1, isoform G K09228|1|8e-31|136|mmu:665211|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0030003//cellular cation homeostasis;GO:0010467//gene expression;GO:0010038//response to metal ion;GO:0030003//cellular cation homeostasis;GO:0010467//gene expression;GO:0010038//response to metal ion;GO:0030003//cellular cation homeostasis;GO:0010467//gene expression;GO:0010038//response to metal ion;GO:0030003//cellular cation homeostasis;GO:0010467//gene expression;GO:0010038//response to metal ion;GO:0030003//cellular cation homeostasis;GO:0010467//gene expression;GO:0010038//response to metal ion 43596 339.00 10.745 6.7 -0.681432482082649 Down 0.537214370624752 CecA1 cecropin A1 - - - GO:0042742//defense response to bacterium 42618 1165.00 22.505 20.33 -0.146635349540819 Down 0.28394531765949 CG5382 CG5382 - GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding GO:0050658//RNA transport 42121 914.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 CG14323 CG14323 - - - - 34147 1248.11 76.73 42.88 -0.839485849104892 Down 0.696770571919165 CG7778 CG7778, isoform B - - - - 14462887 785.00 0.74 0.405 -0.869603362744325 Down 0.194756306960771 19836199 440.00 0.395 1.465 1.89097610624514 Up 0.391658961828028 14462656 462.00 22.36 25.125 0.168203408110463 Up 0.318551050059437 34179 5116.55 4.075 2.94 -0.470983904282076 Down 0.320400211332717 d dachs, isoform E K10359|1|3e-73|278|ame:726683|myosin VII;K10357|2|6e-71|270|tca:663516|myosin V;K10361|3|6e-71|270|ame:408444|myosin XV GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton GO:0030528//transcription regulator activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032559;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0003729//mRNA binding;GO:0030528//transcription regulator activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032559;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0003729//mRNA binding GO:0008298//intracellular mRNA localization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0002164//larval development;GO:0001736//establishment of planar polarity;GO:0040008//regulation of growth;GO:0009798//axis specification;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008298//intracellular mRNA localization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0002164//larval development;GO:0001736//establishment of planar polarity;GO:0040008//regulation of growth;GO:0009798//axis specification;GO:0007476//imaginal disc-derived wing morphogenesis 34500 1380.69 936.44 1049.675 0.164684244759291 Up 0.374224012679963 porin porin, isoform E K05862|1|8e-161|566|dvi:Dvir_GJ17632|voltage-dependent anion channel GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0016021//integral to membrane;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0016021//integral to membrane;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0016021//integral to membrane GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity;GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity;GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity GO:0006811//ion transport;GO:0046907//intracellular transport;GO:0007165//signal transduction;GO:0006811//ion transport;GO:0046907//intracellular transport;GO:0007165//signal transduction;GO:0006811//ion transport;GO:0046907//intracellular transport;GO:0007165//signal transduction 32076 477.00 138.66 145.375 0.0682275260591559 Up 0.197232862237485 CG11752 CG11752 - - - - 43568 569.00 4.25 5.74 0.433587895650624 Up 0.354939902258618 janB janus B K01112|1|2e-10|65.1|gga:770750| [EC:3.1.3.-] - - GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process 44172 1648.00 11.925 15.775 0.403650738977037 Up 0.476852463346982 RabX1 RabX1 K07976|1|6e-146|517|dme:Dmel_CG3870|Rab family, other;K07889|4|3e-35|149|hmg:100197993|Ras-related protein Rab-5C - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction;GO:0006810//transport;GO:0007399//nervous system development 32014 3363.00 10.12 14.64 0.532706263589732 Up 0.527440232465989 CG2202 CG2202 K09228|1|4e-62|240|mmu:627914|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 37155 2046.79 3.715 5.485 0.562129409864597 Up 0.400739664509312 CG15073 CG15073, isoform B K09228|1|2e-33|144|api:100159445|KRAB domain-containing zinc finger protein - - - 19835360 747.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 33646 5842.16 10.025 12.69 0.340089832498823 Up 0.416259410910052 CG15431 CG15431, isoform B - - - - 34059 2226.00 0.04 0.01 -2 Down 0.0694426099590543 CG7179 CG7179 - - - - 14462829 382.00 61.345 70.445 0.19955155144735 Up 0.402852991678774 42988 1584.00 0.145 1.965 3.76040450713103 Up 0.542893937392683 CG13646 CG13646 - GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity - 14462805 2082.00 0.025 0.09 1.84799690655495 Up 0.0883634922731475 19835919 461.00 0.945 0.665 -0.506959988719883 Down 0.158763703605864 34907 1934.00 0.76 1.235 0.700439718141092 Up 0.220446440364549 CG4161 CG4161, isoform B - - - - 39131 1080.00 3.12 4.905 0.65270710735699 Up 0.41114119667151 CG16719 CG16719 - - - - 5740790 353.00 28.165 30.59 0.119156635318654 Up 0.25799101835953 Rpb12 Rpb12 K03009|1|6e-29|125|dya:Dyak_GE12262|DNA-directed RNA Polymerase II subunit K - GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0010467//gene expression 39326 4802.00 1.88 2.245 0.25598278306351 Up 0.158862765816933 Muc68D mucin 68D K01183|1|2e-14|82.4|dme:Dmel_CG18140|chitinase [EC:3.2.1.14];K01873|3|7e-13|77.4|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 43429 1103.00 5.305 4.19 -0.340402507215413 Down 0.298474441949544 CG11837 CG11837 K02528|1|3e-172|604|dsi:Dsim_GD21406|dimethyladenosine transferase [EC:2.1.1.-] GO:0044424//intracellular part GO:0008649//rRNA methyltransferase activity;GO:0008170//N-methyltransferase activity GO:0006364//rRNA processing 3772305 844.00 18.895 14.4 -0.391935706930287 Down 0.489598467837802 CG10731 CG10731, isoform C K02367|1|0.0|1399|dme:Dmel_CG8433|glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] GO:0005789//endoplasmic reticulum membrane GO:0015020//glucuronosyltransferase activity;GO:0005488//binding;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0008375//acetylglucosaminyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0006818//hydrogen transport;GO:0006041//glucosamine metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 39276 1107.00 21.27 20.88 -0.0266983213907879 Down 0.0922599392418439 CG7560 CG7560 K00297|1|0.0|667|dme:Dmel_CG7560|methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20] - GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0000096//sulfur amino acid metabolic process 19835993 428.00 0.815 0.97 0.25118468795605 Up 0.103321886144499 37055 854.00 1.055 1.885 0.837321524561479 Up 0.30537577598732 CG5767 CG5767 - - - - 39490 1389.00 0.635 0.735 0.210987658064198 Up 0.0824858010830802 CG11251 CG11251 - - - - 19835328 4516.00 1.78 1.89 0.086508993254675 Up 0.072810725135385 43426 2431.00 6.21 4.49 -0.467877823479334 Down 0.383205653150178 Cpsf100 cleavage and polyadenylation specificity factor 100 K13148|1|5e-36|153|dre:553648|integrator complex subunit 11 [EC:3.1.27.-] GO:0005849//mRNA cleavage factor complex GO:0003729//mRNA binding;GO:0003824//catalytic activity GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing 8673978 431.00 0.805 0.83 0.044122553232308 Up 0.0480451723682473 CG42621 CG42621 K10359|1|1e-36|150|rno:266714|myosin VII GO:0031513//nonmotile primary cilium;GO:0016461//unconventional myosin complex;GO:0005902//microvillus;GO:0005764//lysosome;GO:0048770;GO:0044459//plasma membrane part GO:0008092//cytoskeletal protein binding;GO:0032559;GO:0042623//ATPase activity, coupled GO:0051648//vesicle localization;GO:0030029//actin filament-based process;GO:0007033//vacuole organization;GO:0050953//sensory perception of light stimulus;GO:0006906//vesicle fusion;GO:0009207;GO:0050954//sensory perception of mechanical stimulus;GO:0060122//inner ear receptor stereocilium organization;GO:0006897//endocytosis;GO:0042471//ear morphogenesis 42410 829.00 0.055 0.12 1.12553088208386 Up 0.0856557918372738 CG4362 CG4362 - GO:0044423 - - 2768873 999.00 0.3 0.11 -1.44745897697122 Down 0.154173821159688 Ste:CG33236 Ste:CG33236 K08282|1|2e-95|347|dme:Dmel_CG33236|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 13084051 573.52 0.405 0.425 0.069540933253077 Up 0.045898824461762 CG43178 CG43178, isoform B - - - - 41205 1384.00 40.19 35.9 -0.162852733348331 Down 0.329910183595298 CG8507 CG8507 - GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0005539//glycosaminoglycan binding;GO:0070325//lipoprotein particle receptor binding - 41622 862.00 0.32 0.56 0.807354922057604 Up 0.157508915598996 CG8141 CG8141 K10666|1|1e-09|63.5|api:100165617|E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19] - - - 32222 3802.15 22.335 14.905 -0.583509879312087 Down 0.586811517633074 Tis11 Tis11 homolog, isoform D K13056|1|2e-24|114|dre:30114|CCCH zinc finger protein C3H-4 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0035194//posttranscriptional gene silencing by RNA;GO:0035194//posttranscriptional gene silencing by RNA 35522 4626.00 1.15 1.37 0.252542032016151 Up 0.119072777704398 BubR1 Bub1-related kinase K02178|1|0.0|2884|dme:Dmel_CG7838|checkpoint serine/threonine-protein kinase [EC:2.7.11.1] GO:0000777//condensed chromosome kinetochore GO:0004672//protein kinase activity;GO:0032559 GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0006464//cellular protein modification process 33081 1789.93 28.21 24.475 -0.204897806094514 Down 0.363723418306697 Cbs cystathionine beta-synthase, isoform C K01697|1|0.0|969|dme:Dmel_CG1753|cystathionine beta-synthase [EC:4.2.1.22] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity GO:0006563//L-serine metabolic process;GO:0019344//cysteine biosynthetic process;GO:0006563//L-serine metabolic process;GO:0019344//cysteine biosynthetic process 47757 1433.00 26.135 30.295 0.213096546267049 Up 0.378714832915071 betaggt-II beta subunit of type II geranylgeranyl transferase K05956|1|0.0|662|dme:Dmel_CG18627|geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] - GO:0003824//catalytic activity - 19835329 230.00 0.88 0.75 -0.230612928141416 Down 0.093547747985735 32437 2162.02 140.77 132.7 -0.0851715381054002 Down 0.236758684453837 Lsd-2 lipid storage droplet-2, isoform F K08768|1|2e-09|64.7|mcc:706465|perilipin GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0010970//microtubule-based transport;GO:0019915//lipid storage;GO:0044238//primary metabolic process;GO:0032879//regulation of localization;GO:0010970//microtubule-based transport;GO:0019915//lipid storage;GO:0044238//primary metabolic process;GO:0032879//regulation of localization;GO:0010970//microtubule-based transport;GO:0019915//lipid storage;GO:0044238//primary metabolic process;GO:0032879//regulation of localization 40170 6481.68 19.705 22.55 0.19456568400491 Up 0.337240787214371 Mi-2 Mi-2, isoform D K11643|1|0.0|3136|dme:Dmel_CG8103|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.1.-] GO:0044427//chromosomal part;GO:0000118//histone deacetylase complex;GO:0044427//chromosomal part;GO:0000118//histone deacetylase complex;GO:0044427//chromosomal part;GO:0000118//histone deacetylase complex GO:0003678//DNA helicase activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding;GO:0032559;GO:0003678//DNA helicase activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding;GO:0032559;GO:0003678//DNA helicase activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding;GO:0032559 GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0034728//nucleosome organization;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0034728//nucleosome organization;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0034728//nucleosome organization 326227 1167.00 0.73 1.77 1.27778099120298 Up 0.365275392946771 CG32650 CG32650 - - - - 317849 1526.00 6.095 6.86 0.170582355552601 Up 0.207634394399683 CG32095 CG32095 - - - - 40003 2816.00 1.505 1.29 -0.222392421336448 Down 0.114416853784176 mus304 mutagen-sensitive 304 K10905|1|5e-07|57.0|mdo:100023426|ATR interacting protein GO:0044424//intracellular part - GO:0006310//DNA recombination;GO:0009628//response to abiotic stimulus;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0033554//cellular response to stress;GO:0031570;GO:0007143//female meiosis;GO:0048513//organ development 41936 1035.00 0.57 0.59 0.0497530351970997 Up 0.0451063267732136 CG5478 CG5478 - - - - 45399 1683.00 15.57 15.015 -0.0523644695218873 Down 0.119303922863558 Aats-trp Tryptophanyl-tRNA synthetase K01867|1|0.0|824|dme:Dmel_CG9735|tryptophanyl-tRNA synthetase [EC:6.1.1.2] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0007033//vacuole organization 35533 2202.00 0.5 0.665 0.411426245726465 Up 0.118907674019284 CG7856 CG7856 - - - - 40130 835.92 57.36 69.49 0.276760356840665 Up 0.48794743098666 CG9231 CG9231, isoform B - GO:0031224//intrinsic to membrane - - 41055 2077.71 5.35 5.82 0.121480261619775 Up 0.149749042398626 CG9839 CG9839, isoform B - - - - 5740687 425.00 0.22 0.51 1.2129937233342 Up 0.18848236692643 CG34338 CG34338 - - - - 37039 1746.00 19.005 15.44 -0.299706272593885 Down 0.429665830141329 olf186-M olf186-M - - - - 41371 525.58 8.47 6.495 -0.383032443884318 Down 0.38739928675208 CG18643 CG18643, isoform C K07560|1|3e-85|313|dme:Dmel_CG18643|D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-] GO:0044424//intracellular part GO:0016787//hydrolase activity GO:0009063//cellular amino acid catabolic process 37420 1754.00 44.465 34.805 -0.353375610693681 Down 0.529025227843085 CG4302 CG4302 K00699|1|0.0|968|dme:Dmel_CG4302|glucuronosyltransferase [EC:2.4.1.17] - - - 2769006 1523.00 0.92 1.93 1.06889508121107 Up 0.350151895390305 CG33234 CG33234, isoform E K06258|1|2e-29|130|api:100167336|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 GO:0031224//intrinsic to membrane - GO:0006810//transport 40235 1161.00 1.35 8.565 2.66549383903317 Up 0.707964601769911 Spn77Bb serpin 77Bb K13963|1|2e-20|100|mcc:701189|serpin B - GO:0004866//endopeptidase inhibitor activity - 31644 703.00 33.88 21.39 -0.663497392167155 Down 0.633205653150178 bou boudin - - - - 31318 1468.03 20.255 26.84 0.406106586513747 Up 0.530246995112931 CG10802 CG10802, isoform B K07050|1|0.0|872|dme:Dmel_CG10802| - - - 38666 2238.00 18.625 18.69 0.00502614350827162 Up 0.0502575617487782 CG10483 CG10483 - GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity - 8673960 361.00 0.595 0.54 -0.139930261144475 Down 0.063102628450667 CG42467 CG42467 - - - - 41711 857.00 7.6 7.28 -0.0620609681322514 Down 0.104345528992207 CCHa1 CCHamide-1 - - - - 31386 1996.00 3.93 4.095 0.059334139382402 Up 0.0806696605468234 CG11436 CG11436 - - - - 33985 718.00 0.98 0.25 -1.97085365434048 Down 0.330141328754458 Pcp pupal cuticle protein - - GO:0005214//structural constituent of chitin-based cuticle - 33571 5107.38 25.74 21.635 -0.250644932798811 Down 0.407244749702813 tim timeless, isoform S K12074|1|0.0|1530|dme:Dmel_CG3234|timeless GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007618//mating;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042331//phototaxis;GO:0007562//eclosion;GO:0006606//protein import into nucleus 34568 4755.09 5.535 7.235 0.386409699750172 Up 0.367652886012416 salr spalt-related, isoform C K09228|1|1e-23|113|gga:776881|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007476//imaginal disc-derived wing morphogenesis 33203 4521.88 12.605 13.69 0.11912632839936 Up 0.209648659358077 Pi3K21B Pi3K21B, isoform E K02649|1|0.0|896|dme:Dmel_CG2699|phosphoinositide-3-kinase, regulatory subunit GO:0005942//phosphatidylinositol 3-kinase complex GO:0019207//kinase regulator activity;GO:0019899//enzyme binding GO:0040008//regulation of growth;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008361//regulation of cell size;GO:0016310//phosphorylation;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process 32682 3433.02 55.31 33.16 -0.738096335220175 Down 0.674547615902787 CG4928 CG4928, isoform C - GO:0016020//membrane;GO:0016020//membrane - GO:0006810//transport;GO:0006810//transport 41393 1458.00 5.885 5.205 -0.177144251739027 Down 0.198784836877559 CG14710 CG14710 K09228|1|2e-31|136|cfa:606925|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19835488 310.00 0.145 0.65 2.16438681790088 Up 0.277143045832783 - CG45122 - - - - 31489 2020.00 15.375 16.36 0.0895863378277841 Up 0.178146876238278 CG3149 CG3149 K06316|1|0.0|923|dme:Dmel_CG3149|oligosaccharidyl-lipid flippase family - - - 40026 1548.00 0.98 0.745 -0.395541323653046 Down 0.13693699643376 CG18231 CG18231 K00472|1|4e-81|302|dan:Dana_GF23629|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 40240 1811.74 88.48 87.285 -0.0196176387622278 Down 0.088924844802536 eRF1 eukaryotic release factor 1, isoform I K03265|1|0.0|839|dmo:Dmoj_GI13383|peptide chain release factor eRF subunit 1 GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0003747//translation release factor activity;GO:0003747//translation release factor activity;GO:0003747//translation release factor activity;GO:0003747//translation release factor activity;GO:0003747//translation release factor activity;GO:0003747//translation release factor activity GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006886//intracellular protein transport;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006886//intracellular protein transport;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006886//intracellular protein transport;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006886//intracellular protein transport;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006886//intracellular protein transport;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation;GO:0048102//autophagic cell death;GO:0006886//intracellular protein transport;GO:0007166//cell surface receptor signaling pathway 36348 1540.71 9.345 3.66 -1.35235101546112 Down 0.634988772949412 Cpr49Ac cuticular protein 49Ac, isoform G - - GO:0048037//cofactor binding;GO:0042302//structural constituent of cuticle;GO:0003824//catalytic activity;GO:0042302//structural constituent of cuticle;GO:0042302//structural constituent of cuticle - 37549 4220.40 203.45 137.82 -0.561889017861993 Down 0.660150574560824 Gp150 Gp150, isoform F K06260|1|7e-30|133|dre:100148153|platelet glycoprotein V - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0001654//eye development;GO:0002118//aggressive behavior;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0001654//eye development;GO:0002118//aggressive behavior;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0001654//eye development;GO:0002118//aggressive behavior;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0001654//eye development;GO:0002118//aggressive behavior;GO:0007167//enzyme linked receptor protein signaling pathway 38503 848.00 27.17 18.665 -0.541679056918905 Down 0.588990886276582 VhaM9.7-c vacuolar H[+] ATPase M9.7 subunit c K02153|1|2e-36|152|dme:Dmel_CG11589|V-type H+-transporting ATPase subunit H [EC:3.6.3.14] GO:0033176 GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient 37993 5430.65 10.73 13.29 0.308691028519653 Up 0.398758420287941 CG12851 CG12851, isoform D - - - - 5740605 688.00 0.645 0.53 -0.283306800860055 Down 0.0949346189406948 CG34279 CG34279, isoform C - - - - 117369 1996.92 913.3 950.49 0.057582615231481 Up 0.185378417646282 desat1 desaturase 1, isoform E K00507|1|0.0|724|dme:Dmel_CG5887|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part GO:0016215;GO:0016215;GO:0016215;GO:0016215;GO:0016215 GO:0042446//hormone biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0042446//hormone biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0042446//hormone biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0042446//hormone biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0042446//hormone biosynthetic process;GO:0006631//fatty acid metabolic process 19834815 436.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 39825 2345.05 0.615 0.39 -0.657112286476991 Down 0.143739268260468 CG13035 CG44836, isoform F - - - - 318826 1958.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 CG33003 CG33003, isoform B - - - - 31718 3771.90 13.35 19.675 0.559523893819932 Up 0.569706775855237 Tbh tyramine beta hydroxylase, isoform C K00503|1|0.0|1268|dme:Dmel_CG1543|dopamine beta-monooxygenase [EC:1.14.17.1] - - - 34362 2252.05 16.48 14.435 -0.191145134947237 Down 0.310427948751816 CG5694 CG5694, isoform B K11831|1|1e-08|62.4|dwi:Dwil_GK10971|nuclear respiratory factor 1 - - - 5740212 839.00 0.515 0.21 -1.29418310440446 Down 0.199181085721833 CG34274 CG34274 K09553|1|5e-08|58.2|dpe:Dper_GL25924|stress-induced-phosphoprotein 1 - - - 2768673 1336.00 0.16 0.175 0.129283016944966 Up 0.0491348566900013 att-ORFB alternative testis transcripts open reading frame B K05863|1|3e-23|109|spu:575225|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 19836223 601.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 36306 744.00 13.455 15.27 0.182557671156434 Up 0.293026020340774 SmD3 small ribonucleoprotein particle protein SmD3 K11088|1|8e-42|170|dvi:Dvir_GJ19907|small nuclear ribonucleoprotein D3 GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0005515//protein binding GO:0000278//mitotic cell cycle;GO:0048534;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0000398//mRNA splicing, via spliceosome 41136 1055.88 24.635 21.83 -0.174397341321393 Down 0.319244485536917 RhoL Rho-like, isoform B K04392|1|1e-52|206|hmg:100206675|Ras-related C3 botulinum toxin substrate 1 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding;GO:0032561//guanyl ribonucleotide binding GO:0065008;GO:0009888//tissue development;GO:0035556//intracellular signal transduction;GO:0007297//ovarian follicle cell migration;GO:0033554//cellular response to stress 12797890 612.00 15.4 11.58 -0.411295097593027 Down 0.478536520935147 CG14742 CG14742 - - - - 32586 523.00 637.18 670.54 0.0736224125585171 Up 0.204959714700832 CG3560 CG3560 K00417|1|3e-54|210|dya:Dyak_GE17257|ubiquinol-cytochrome c reductase subunit 7 [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity GO:0006979//response to oxidative stress;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain;GO:0017062//respiratory chain complex III assembly 41408 2781.00 8.92 7.86 -0.182514397661698 Down 0.241579712059173 CG6830 CG6830 - - - - 38032 3091.54 12.245 12.745 0.0577385994582238 Up 0.123695680887597 CG7028 CG7028, isoform E K08286|1|0.0|1475|dme:Dmel_CG7028|protein-serine/threonine kinase [EC:2.7.11.-];K08827|2|0.0|1454|dse:Dsec_GM14295|serine/threonine-protein kinase PRP4 [EC:2.7.11.1] GO:0005681//spliceosomal complex GO:0004672//protein kinase activity;GO:0032559 GO:0065008;GO:0000377;GO:0006464//cellular protein modification process 42595 2345.05 9.075 7.795 -0.219348620185328 Down 0.278595958261788 pit pitchoune, isoform C K13179|1|0.0|1070|dme:Dmel_CG6375|ATP-dependent RNA helicase DDX18 [EC:3.6.4.13] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559 - 31261 2425.00 15.115 20.025 0.405821263668365 Up 0.504556861709153 CG2701 CG2701 - - - - 34295 1662.00 0.325 0.035 -3.21501289097085 Down 0.225597675340114 CG44152 pickpocket 18 K04832|1|8e-07|55.1|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04827|2|3e-06|53.1|gga:416579|nonvoltage-gated sodium channel 1 gamma GO:0044464//cell part GO:0005261//cation channel activity GO:0030001//metal ion transport 317928 393.22 994.19 916.175 -0.11789839604324 Down 0.305408796724343 CG32230 CG32230, isoform C K03948|1|1e-44|177|dme:Dmel_CG32230|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H - 317835 1364.00 2.075 1.935 -0.100777770089877 Down 0.0813300752872804 CG32040 CG32040 - - - - 10178857 642.00 0.685 0.42 -0.705714660181767 Down 0.163452648263109 CG42692 CG42692, isoform B - - - - 33261 1533.00 10.805 10.45 -0.0481961298912622 Down 0.104411570466253 CG3862 CG3862 K10614|1|2e-27|124|gga:422514|E3 ubiquitin-protein ligase HERC3 [EC:6.3.2.19];K10615|4|3e-27|123|xla:446573|E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19] - - - 35553 1251.00 1.775 1.635 -0.118528388893962 Down 0.0851935015189539 tomboy40 tomboy40 K11518|1|0.0|634|der:Dere_GG23200|mitochondrial import receptor subunit TOM40 GO:0031966//mitochondrial membrane GO:0004871//signal transducer activity;GO:0008320//protein transmembrane transporter activity;GO:0005244//voltage-gated ion channel activity GO:0006811//ion transport;GO:0006605//protein targeting 40569 2418.00 9.255 7.8 -0.246758866120963 Down 0.302040681548012 Fip1 Fip1 K12824|1|9e-20|99.0|dwi:Dwil_GK10926|transcription elongation regulator 1 GO:0043231//intracellular membrane-bounded organelle - GO:0008334//histone mRNA metabolic process 34447 2261.00 4.665 3.5 -0.41452215901943 Down 0.315909391097609 CG7384 CG7384 - - - - 36833 2698.59 2.005 3.15 0.651749591932359 Up 0.339816404702153 CG6262 CG6262, isoform C K01194|1|2e-17|91.3|dme:Dmel_CG6262|alpha,alpha-trehalase [EC:3.2.1.28] - GO:0015927//trehalase activity;GO:0015927//trehalase activity;GO:0015927//trehalase activity GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process 19835340 2102.00 0.8 0.855 0.0959244199985353 Up 0.0586118082155594 10178801 916.37 4.14 7.065 0.771058792834614 Up 0.504490820235108 36584 2001.00 21.43 22.215 0.0519022913334563 Up 0.130464931977282 CG8531 CG8531 K09531|1|0.0|1002|dme:Dmel_CG8531|DnaJ homolog subfamily C member 11 - GO:0005515//protein binding - 31268 3837.00 5.72 5.88 0.0398010080579749 Up 0.0744617619865275 crm cramped, isoform B - - - - 318623 3444.00 1.22 1.135 -0.104188850271971 Down 0.0668339717342491 GluRIIE glutamate receptor IIE K05313|1|0.0|1712|dme:Dmel_CG31201|glutamate receptor, ionotropic, invertebrate;K05202|5|5e-133|476|xla:100294518|glutamate receptor, ionotropic, kainate 2 GO:0031224//intrinsic to membrane;GO:0030313;GO:0044459//plasma membrane part GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0060024//rhythmic synaptic transmission 12797873 376.00 1.47 1.025 -0.520192245330918 Down 0.204629507330604 CG43349 CG43349, isoform B - - - - 32104 2235.00 6.38 5.895 -0.114064610785107 Down 0.148131026284507 CG11696 CG11696 K09228|1|9e-31|135|cfa:612509|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 12797909 1179.00 0.305 0.7 1.19854567938208 Up 0.22242768458592 41373 1666.53 13 12.705 -0.033115247862462 Down 0.0854246466781138 CG5276 CG5276, isoform B K12304|1|0.0|860|dme:Dmel_CG5276|soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] - GO:0016462//pyrophosphatase activity;GO:0046872//metal ion binding - 43111 1958.00 0.105 0.14 0.415037499278844 Up 0.0678576145819575 CG17197 CG17197 - - GO:0046872//metal ion binding - 19835876 476.00 1.175 1.345 0.194945415991624 Up 0.101406683397173 - CG44261 - - - - 19834757 863.00 0.05 0.105 1.0703893278914 Up 0.0856557918372738 - CG44335 - - - - 38863 13938.41 83.15 128.285 0.625564321438105 Up 0.670155857878748 Ank2 ankyrin 2, isoform Z K10380|1|0.0|2927|dya:Dyak_GE20395|ankyrin GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0016020//membrane GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth;GO:0048741//skeletal muscle fiber development;GO:0023060;GO:0007010//cytoskeleton organization;GO:0048588//developmental cell growth 19835976 2349.00 20.885 22.015 0.0760197007741007 Up 0.17573636243561 35370 2656.00 26.82 40.245 0.585500318077204 Up 0.6255778628979 tadr torn and diminished rhabdomeres, isoform D K13871|1|2e-10|68.2|cfa:488161|solute carrier family 7 (cationic amino acid transporter), member 14;K13866|3|5e-10|67.0|dwi:Dwil_GK17226|solute carrier family 7 (cationic amino acid transporter), member 4 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0015837//amine transport;GO:0015837//amine transport 19835526 603.00 0.89 0.255 -1.8033080889949 Down 0.30583806630564 43718 4507.00 6.665 6.975 0.0655883416275766 Up 0.106557918372738 pygo pygopus - - GO:0046914//transition metal ion binding GO:0009987//cellular process;GO:0016055//Wnt receptor signaling pathway;GO:0007444//imaginal disc development;GO:0009653//anatomical structure morphogenesis 34605 589.00 0.62 0.7 0.175086706558091 Up 0.0756505085193502 CG16964 CG16964, isoform B - - - - 42387 3925.50 12 21.73 0.856653768685402 Up 0.646017699115044 CG4836 CG4836, isoform E K00008|1|1e-44|182|aag:AaeL_AAEL011112|L-iditol 2-dehydrogenase [EC:1.1.1.14] - GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 5740505 2870.00 1.765 2.12 0.264396081292019 Up 0.157178708228768 CG34411 CG34411, isoform C K04306|1|3e-105|383|bfo:BRAFLDRAFT_134702|leucine-rich repeat-containing G protein-coupled receptor 7;K04307|3|3e-95|350|mmu:140498|leucine-rich repeat-containing G protein-coupled receptor 8 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 14462622 1508.00 0.055 2.59 5.55737666904926 Up 0.660480781931053 CG43742 CG43742 - - - - 32252 1959.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 CG12715 CG12715, isoform B - - - - 34215 2052.15 23.91 27.8 0.217470752899242 Up 0.381983885880333 C1GalTA core 1 galactosyltransferase A, isoform C K00731|1|0.0|815|dme:Dmel_CG9520|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0048531//beta-1,3-galactosyltransferase activity;GO:0048531//beta-1,3-galactosyltransferase activity;GO:0048531//beta-1,3-galactosyltransferase activity GO:0016266//O-glycan processing;GO:0009653//anatomical structure morphogenesis;GO:0006664//glycolipid metabolic process;GO:0016266//O-glycan processing;GO:0009653//anatomical structure morphogenesis;GO:0006664//glycolipid metabolic process;GO:0016266//O-glycan processing;GO:0009653//anatomical structure morphogenesis;GO:0006664//glycolipid metabolic process 37535 2755.00 3.325 2.98 -0.15804200992639 Down 0.140106987187954 MED16 mediator complex subunit 16 - GO:0043231//intracellular membrane-bounded organelle GO:0016251//general RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding GO:0006352//DNA-dependent transcription, initiation 34751 1928.01 59.945 71.66 0.257528619784602 Up 0.468201030246995 loqs loquacious, isoform F - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0042078//germ-line stem cell division;GO:0007399//nervous system development;GO:0019827//stem cell maintenance;GO:0016246//RNA interference;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0042078//germ-line stem cell division;GO:0007399//nervous system development;GO:0019827//stem cell maintenance;GO:0016246//RNA interference;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0042078//germ-line stem cell division;GO:0007399//nervous system development;GO:0019827//stem cell maintenance;GO:0016246//RNA interference;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0042078//germ-line stem cell division;GO:0007399//nervous system development;GO:0019827//stem cell maintenance;GO:0016246//RNA interference 34507 655.47 0.76 0.975 0.359402800306025 Up 0.12963941355171 CG14071 CG14071, isoform C - - - - 40139 1035.00 15.11 16.87 0.158956313122737 Up 0.276548672566372 CG9376 CG9376 K05287|1|3e-12|72.8|bfo:BRAFLDRAFT_211692|phosphatidylinositol glycan, class F [EC:2.7.-.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane - GO:0006497//protein lipidation 40528 1590.00 65.26 37.615 -0.794890897064451 Down 0.686699247127196 DhpD dihydropterin deaminase K01487|1|0.0|833|dme:Dmel_CG18143|guanine deaminase [EC:3.5.4.3] - GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding - 37257 984.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 CG15905 CG15905, isoform C - - - - 326193 1529.00 4.6 5.22 0.182415945625509 Up 0.190265486725664 Alg10 alpha 3 glucosyltransferase K03850|1|0.0|832|dme:Dmel_CG32076|alpha-1,2-glucosyltransferase [EC:2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006486//protein glycosylation 43646 1213.00 0.255 0.01 -4.6724253419715 Down 0.24085325584467 CG11313 CG11313, isoform D K01312|1|2e-61|236|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|9e-42|171|dpo:Dpse_GA18526| [EC:3.4.21.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides - 34205 3063.00 0.32 1.745 2.44708322620965 Up 0.457766477347774 CG9466 CG9466, isoform B K12311|1|0.0|1954|dme:Dmel_CG9466|lysosomal alpha-mannosidase [EC:3.2.1.24] - GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0019318//hexose metabolic process 3772602 537.00 0.08 0.01 -3 Down 0.110718531237617 CG33757 CG33757 K12602|1|5e-14|77.0|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 43819 2237.22 46.745 49.05 0.0694410786309626 Up 0.184090608902391 pho pleiohomeotic, isoform B K09201|1|0.0|1062|dme:Dmel_CG17743|transcription factor YY - - - 32414 2265.00 11.735 5.76 -1.02667712508086 Down 0.620723814555541 CG9521 CG9521 K00108|1|0.0|816|dme:Dmel_CG9519|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 34427 1392.19 56.72 48.76 -0.218159406619304 Down 0.418405758816537 KdelR KDEL receptor, isoform C K10949|1|2e-117|422|dse:Dsec_GM18383|ER lumen protein retaining receptor GO:0005798//Golgi-associated vesicle;GO:0031224//intrinsic to membrane;GO:0005798//Golgi-associated vesicle;GO:0031224//intrinsic to membrane;GO:0005798//Golgi-associated vesicle;GO:0031224//intrinsic to membrane GO:0046923//ER retention sequence binding;GO:0004871//signal transducer activity;GO:0046923//ER retention sequence binding;GO:0004871//signal transducer activity;GO:0046923//ER retention sequence binding;GO:0004871//signal transducer activity GO:0048193//Golgi vesicle transport;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0048193//Golgi vesicle transport;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0048193//Golgi vesicle transport;GO:0035437//maintenance of protein localization in endoplasmic reticulum 36264 7606.00 8.065 8.415 0.0612887381743064 Up 0.108175934486858 Mtor megator, isoform B K09291|1|0.0|3725|dme:Dmel_CG8274|nucleoprotein TPR GO:0005635//nuclear envelope;GO:0044430//cytoskeletal part - GO:0006605//protein targeting;GO:0007051//spindle organization 43695 652.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 CG15563 CG15563 - - - - 59225 808.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 CG17234 CG17234 K01312|1|2e-41|168|dpo:Dpse_GA14937|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40084 1328.00 22.195 16.51 -0.426894588411835 Down 0.525822216351869 CG11577 CG11577 K00552|1|1e-35|150|gga:769542|glycine N-methyltransferase [EC:2.1.1.20] - - - 42588 751.00 22.045 19.66 -0.165188155275167 Down 0.308083476423194 mRpL35 mitochondrial ribosomal protein L35 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 33568 1964.00 0.175 0.09 -0.959358015502654 Down 0.0946374323074891 CG31776 CG31776 K00710|1|0.0|1254|dme:Dmel_CG31776|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process 59143 1408.00 0.14 0.135 -0.0524674198941354 Down 0.0382380134724607 CG18747 CG18747 - - - GO:0050877//neurological system process;GO:0023060 53580 691.27 5.145 4.64 -0.149046271766396 Down 0.164410249636772 Dip1 dorsal interacting protein 1, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding - 32992 3003.39 68.985 62.615 -0.139774388991578 Down 0.317263241315546 Pmp70 Pmp70, isoform D K05677|1|0.0|1300|dme:Dmel_CG12703|ATP-binding cassette, subfamily D (ALD), member 3 GO:0031231//intrinsic to peroxisomal membrane;GO:0043234//protein complex GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 49045 4643.17 28.255 27.62 -0.0327928695927155 Down 0.100746268656716 Gprk2 G protein-coupled receptor kinase 2, isoform B K08291|1|0.0|1231|dsi:Dsim_GD21578|G protein-coupled receptor kinase [EC:2.7.11.16] GO:0044424//intracellular part;GO:0016020//membrane GO:0004674//protein serine/threonine kinase activity;GO:0060089;GO:0032559 GO:0003002//regionalization;GO:0007224//smoothened signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007028//cytoplasm organization;GO:0006464//cellular protein modification process 37967 1418.38 43.58 35.915 -0.279079680932179 Down 0.469488838990886 key kenny, isoform B K07210|1|1e-08|61.2|ecb:100058432|inhibitor of nuclear factor kappa-B kinase gamma subunit GO:0044464//cell part GO:0046914//transition metal ion binding - 38262 1139.84 102.75 90.365 -0.185302389869036 Down 0.399253731343284 CG1927 CG1927, isoform B - - - - 14462395 394.00 0.12 0.01 -3.58496250072116 Down 0.14562145027077 40352 876.00 0.32 0.055 -2.5405683813627 Down 0.197596090344736 Cpr78Ca cuticular protein 78Ca - - GO:0005198//structural molecule activity - 32112 2992.60 15.515 13.635 -0.186348996613456 Down 0.302998282921675 CG1703 CG1703, isoform B K06184|1|0.0|1045|dme:Dmel_CG1703|ATP-binding cassette, sub-family F, member 1 GO:0043234//protein complex GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 36528 662.00 23.175 22.32 -0.0542323116837055 Down 0.132578259146744 CG13339 CG13339 - - - - 3772691 571.89 66.85 54.57 -0.292819516608072 Down 0.497028133667943 Kaz1-ORFB Kaz1-ORFB, isoform H - - - GO:0006508//proteolysis;GO:0006508//proteolysis;GO:0006508//proteolysis;GO:0006508//proteolysis 31841 1101.00 10.31 10.64 0.0454538181330812 Up 0.100944393078854 CG7039 ADP-ribosylation factor related protein 1 K07952|1|3e-113|408|dme:Dmel_CG7039|ADP-ribosylation factor related protein 1 GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 41081 1719.97 1.74 2.295 0.39940684756508 Up 0.217507594769515 CG11983 CG11983, isoform B - - - - 33210 3564.00 2.08 2.425 0.221401218933398 Up 0.147074362699775 RpI135 RNA polymerase I 135kD subunit K03002|1|0.0|2291|dme:Dmel_CG4033|DNA-directed RNA polymerase I subunit A2 [EC:2.7.7.6] GO:0044452 GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0001882//nucleoside binding GO:0006351//transcription, DNA-dependent 10178803 1344.07 24.955 27.96 0.164035456873944 Up 0.313399815083873 31101 1289.00 29.72 23.385 -0.345850687119655 Down 0.503731343283582 pck pickel, isoform D - - - - 19835344 1031.00 0.04 0.09 1.16992500144231 Up 0.0797781006472064 42551 1222.00 7.345 5.66 -0.375960437724398 Down 0.364912164839519 CG6353 CG6353 - - - - 3354861 1946.30 51.05 53.945 0.0795782857373371 Up 0.204992735437855 MFS17 major facilitator superfamily transporter 17, isoform J K08193|1|3e-74|280|tca:663951|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 37595 496.00 1.785 0.685 -1.38174818106857 Down 0.379903579447893 CG30196 CG30196 - - - - 19835175 727.00 0.06 0.135 1.16992500144231 Up 0.0983357548540483 37116 5415.34 55.06 42.85 -0.361709405595699 Down 0.544247787610619 Dp1 Dodeca-satellite-binding protein 1, isoform H K12886|1|1e-13|80.5|bmy:Bm1_48315|heterogeneous nuclear ribonucleoprotein K;K13210|2|1e-12|77.0|hmg:100213921|far upstream element-binding protein - - - 35417 2074.93 76.01 79.25 0.0602217008885762 Up 0.173292827895919 CG2201 CG2201, isoform G K00866|1|8e-127|454|dme:Dmel_CG2201|choline kinase [EC:2.7.1.32];K00894|1|8e-127|454|dme:Dmel_CG2201|ethanolamine kinase [EC:2.7.1.82] - GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 32680 1700.00 2.565 1.025 -1.32333491610161 Down 0.436732267864219 CG4880 CG4880, isoform B - - - - 38085 1370.00 19.615 21.46 0.129692740679426 Up 0.254854048342359 Vti1 VTI1 ortholog K08493|1|2e-108|392|dme:Dmel_CG3279|vesicle transport through interaction with t-SNAREs 1 GO:0016020//membrane GO:0005488//binding GO:0015031//protein transport 33757 4275.80 16.88 18.155 0.105052026093022 Up 0.212125214634791 Bsg25D Blastoderm-specific gene 25D, isoform H K00688|1|2e-16|89.0|tgu:100231603|starch phosphorylase [EC:2.4.1.1];K10352|2|3e-09|65.1|ecb:100054482|myosin heavy chain - - - 19835647 2782.00 1.83 1.81 -0.0158539512008371 Down 0.0440166424514595 32317 977.00 0.295 0.605 1.03622018791275 Up 0.193138290846652 BthD BthD selenoprotein - - - - 318788 2704.00 0.595 1.105 0.893084796083488 Up 0.243131686699247 CG31533 CG31533 - - - - 14462721 2541.00 18.55 19.93 0.103522523330892 Up 0.206643772288997 37177 3403.00 9.315 9.46 0.0222844143977574 Up 0.063333773609827 CG15100 CG15100 K01874|1|0.0|1868|dme:Dmel_CG15100|methionyl-tRNA synthetase [EC:6.1.1.10] - - - 43180 1564.00 7.62 4.585 -0.732869263898267 Down 0.505811649716022 CG6073 CG6073, isoform B - - - - 44011 5217.46 2.13 1.625 -0.390413712310021 Down 0.207040021133272 pwn pawn, isoform C K02599|1|7e-10|67.0|hsa:4854|Notch - - - 38373 3524.36 58.695 68.62 0.225391514935704 Up 0.436567164179104 CG11537 CG11537, isoform G K08214|1|2e-08|62.0|nve:NEMVE_v1g113330|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008493//tetracycline transporter activity;GO:0008493//tetracycline transporter activity;GO:0008493//tetracycline transporter activity;GO:0008493//tetracycline transporter activity;GO:0008493//tetracycline transporter activity GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus;GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus;GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus;GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus;GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus 39216 912.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 CG12523 CG12523, isoform B - - - - 37367 3267.00 2.765 3.035 0.134417036020975 Up 0.11666226390173 Rx retinal homeobox K09332|1|1e-36|155|dre:30474|retina and anterior neural fold homeobox protein - - - 33434 2256.74 18.89 17.86 -0.0808906212671469 Down 0.171674811781799 Slh SLY-1 homologous, isoform G K12479|1|1e-20|101|nve:NEMVE_v1g229729|vacuolar protein sorting-associated protein 45 GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005515//protein binding;GO:0005515//protein binding GO:0006909//phagocytosis;GO:0048278//vesicle docking;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0015031//protein transport;GO:0006909//phagocytosis;GO:0048278//vesicle docking;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0015031//protein transport 48309 4868.00 1.5 1.59 0.0840642647884743 Up 0.0667679302602034 mus101 mutagen-sensitive 101 K10728|1|0.0|2768|dme:Dmel_CG11156|topoisomerase (DNA) II binding protein 1 GO:0044464//cell part - GO:0007292//female gamete generation 43748 1317.00 9.14 10.115 0.146230249500213 Up 0.219191652357681 CG2126 CG2126, isoform B - - - - 39541 355.00 0.27 0.14 -0.947532580105864 Down 0.11828028001585 CG13738 CG13738 - - - - 14462630 2348.41 0.185 0.11 -0.750021746991652 Down 0.0923590014529124 CG43776 CG43776, isoform B - - - - 34394 1473.00 55.205 48.395 -0.189940938926841 Down 0.382479196935676 CG5037 CG5037 K02257|1|0.0|780|dme:Dmel_CG5037|protoheme IX farnesyltransferase [EC:2.5.1.-] GO:0005740//mitochondrial envelope;GO:0031224//intrinsic to membrane GO:0004311//farnesyltranstransferase activity GO:0006783//heme biosynthetic process 43043 1402.00 16.285 15.16 -0.103273966224812 Down 0.194756306960771 CG10425 CG10425 K04708|1|6e-146|517|dpo:Dpse_GA10311|3-dehydrosphinganine reductase [EC:1.1.1.102] - GO:0003824//catalytic activity GO:0008152//metabolic process 14462565 1134.00 0.77 0.735 -0.0671141958585371 Down 0.0525359926033549 35677 1464.28 10.185 5.965 -0.77185193727066 Down 0.55537577598732 Coop corepressor of pangolin, isoform B - - GO:0003676//nucleic acid binding - 43417 3105.00 16.125 19.01 0.237459371450573 Up 0.372308809932638 CG14521 CG14521 K06774|1|2e-23|111|ecb:100064766|neurotrimin - - - 42256 7607.00 11.355 10.26 -0.146296975099834 Down 0.230055474838198 CG14299 CG14299, isoform D - - - - 32361 774.00 0.57 0.305 -0.902152676601855 Down 0.168405758816537 CG1368 CG1368 - - - - 34082 1270.00 0.335 0.47 0.488499661219865 Up 0.111742174085326 Spn28Da serpin 28Da K13963|1|4e-76|285|dse:Dsec_GM20904|serpin B - GO:0004866//endopeptidase inhibitor activity - 40699 3263.21 40.015 50.48 0.335171001094271 Up 0.527374190991943 Xe7 Xe7, isoform E K13169|1|0.0|840|dsi:Dsim_GD19591|splicing factor, arginine/serine-rich 17 - - - 12798341 261.00 2.5 2.625 0.070389327891398 Up 0.0725795799762251 CG43109 CG43109 - - - - 38036 502.69 24.875 23.48 -0.0832641172083214 Down 0.183859463743231 CG13877 CG13877, isoform C - - - - 246505 929.85 0.715 1.565 1.13014751015423 Up 0.326013736626601 CG42559 CG42559, isoform C - - - - 35408 3374.81 800.19 904.095 0.17613177593603 Up 0.403777572315414 nrv3 nervana 3, isoform E K01540|1|0.0|665|dse:Dsec_GM23414|sodium/potassium-transporting ATPase subunit beta GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0008556//potassium-transporting ATPase activity;GO:0008556//potassium-transporting ATPase activity;GO:0008556//potassium-transporting ATPase activity GO:0009206;GO:0030001//metal ion transport;GO:0009206;GO:0030001//metal ion transport;GO:0009206;GO:0030001//metal ion transport 42139 831.93 13.155 10.77 -0.288592998621682 Down 0.381125346717739 CG7713 CG7713, isoform B - - - - 318983 1069.53 17.83 18.695 0.0683457682331742 Up 0.153711530841368 CG31855 CG31855, isoform B K11792|1|3e-43|175|dya:Dyak_GE18649|DET1- and DDB1-associated protein 1 - - - 39932 2367.00 0.01 0.04 2 Up 0.0694426099590543 brv2 brivido-2, isoform B K04988|1|3e-21|103|dre:497373|polycystin 1L2;K04989|3|1e-19|98.6|mmu:244646|polycystin 1L3 GO:0044464//cell part GO:0046872//metal ion binding;GO:0005261//cation channel activity - 3355013 2386.28 56.895 62.47 0.13486165755012 Up 0.299498084797253 Gprk1 G protein-coupled receptor kinase 1, isoform C K00910|1|0.0|1382|dme:Dmel_CG40129|beta-adrenergic-receptor kinase [EC:2.7.11.15] - GO:0004674//protein serine/threonine kinase activity;GO:0004871//signal transducer activity;GO:0005543//phospholipid binding;GO:0005102//receptor binding;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0004871//signal transducer activity;GO:0005543//phospholipid binding;GO:0005102//receptor binding;GO:0032559 GO:0003002//regionalization;GO:0006796//phosphate-containing compound metabolic process;GO:0016059//deactivation of rhodopsin mediated signaling;GO:0006464//cellular protein modification process;GO:0003002//regionalization;GO:0006796//phosphate-containing compound metabolic process;GO:0016059//deactivation of rhodopsin mediated signaling;GO:0006464//cellular protein modification process 35125 1873.00 6.495 4.385 -0.566752683003148 Down 0.42979791308942 CG10341 CG10341, isoform C K12398|1|8e-12|72.4|bmy:Bm1_30830|AP-3 complex subunit mu - - - 36958 1462.00 42.05 45.71 0.120404018461528 Up 0.273345661075155 CG18467 CG18467 - - - - 3885655 980.00 0.165 0.01 -4.04439411935845 Down 0.184883106590939 CG34040 CG34040 - - - - 37838 2225.88 11.5 11.925 0.0523554050611365 Up 0.110718531237617 MAN1 MAN1, isoform C - GO:0031229;GO:0031229 GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0030509//BMP signaling pathway;GO:0006396//RNA processing;GO:0030509//BMP signaling pathway;GO:0006396//RNA processing 318082 1606.71 37.6 43.78 0.219539292615947 Up 0.407839122969225 CG32544 CG32544, isoform B - - - - 40444 1548.69 857.205 457.015 -0.907398747414836 Down 0.72833839651301 Act79B actin 79B, isoform B K05692|1|0.0|748|nvi:100117792|actin beta/gamma 1 GO:0015629//actin cytoskeleton GO:0032559 GO:0006909//phagocytosis;GO:0030239//myofibril assembly 35357 690.33 69.185 114.875 0.731533675351438 Up 0.689605071985207 CG9338 CG9338, isoform B K06846|1|1e-06|53.1|dpo:Dpse_GA19698|lymphocyte antigen 6 complex GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity GO:0015837//amine transport 47942 3558.00 9.19 11.1 0.272422909948434 Up 0.344538370096421 scat scattered - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0006892//post-Golgi vesicle-mediated transport;GO:0003006//developmental process involved in reproduction;GO:0016197//endosomal transport 40266 4897.67 4.195 5.25 0.323646612113662 Up 0.285761458195747 CG5195 artichoke, isoform C K05401|1|0.0|2803|dme:Dmel_CG5195|toll-like recepto 3 - GO:0005488//binding - 50441 514.00 0.085 0.285 1.7454271729144 Up 0.162528067626469 CG18666 CG18666 - - - - 31369 921.00 0.55 0.755 0.457045025800419 Up 0.131125346717739 CG15576 CG15576 - - - - 47260 3144.96 19.14 19.27 0.00976574180969553 Up 0.0570268128384626 l(3)05822 lethal (3) 05822, isoform D K07364|1|9e-07|56.2|dre:571588|tec protein tyrosine kinase [EC:2.7.10.2];K11247|2|1e-06|55.5|api:100169394|endophilin-A;K04705|3|2e-06|54.7|nvi:100119432|signal transducing adaptor molecule;K07365|4|3e-06|54.3|cel:ZK470.5|NCK adaptor protein;K07366|5|3e-06|54.3|gga:770756|GRB2-related adaptor protein 2 - - - 19836246 609.00 0.535 0.56 0.0658879356564573 Up 0.049432043323207 32157 3776.00 18.68 22.905 0.294168107808346 Up 0.437755910711927 CG10362 CG10362 - GO:0044464//cell part GO:0043169//cation binding GO:0023033 43163 2243.00 13.72 13.34 -0.0405218149882272 Down 0.100250957601374 exo84 Exo84 ortholog, isoform B - GO:0043234//protein complex;GO:0043234//protein complex - GO:0006903//vesicle targeting;GO:0000212//meiotic spindle organization;GO:0035090//maintenance of apical/basal cell polarity;GO:0001505//regulation of neurotransmitter levels;GO:0032506;GO:0033206//cytokinesis after meiosis;GO:0006904//vesicle docking involved in exocytosis;GO:0006903//vesicle targeting;GO:0000212//meiotic spindle organization;GO:0035090//maintenance of apical/basal cell polarity;GO:0001505//regulation of neurotransmitter levels;GO:0032506;GO:0033206//cytokinesis after meiosis;GO:0006904//vesicle docking involved in exocytosis 31481 3805.41 12.275 12.36 0.00995571870231915 Up 0.0526350548144235 CG4119 CG4119, isoform B K12822|1|2e-155|550|dme:Dmel_CG4119|RNA-binding protein 25 - - - 43823 785.95 122.435 105.51 -0.214636293609683 Down 0.428345000660415 Arf102F ADP ribosylation factor at 102F, isoform B K07977|1|5e-100|363|dsi:Dsim_GD20493|Arf/Sar family, other - - - 36038 1526.00 5.81 3.86 -0.589937316136449 Down 0.419858671245542 CG12134 CG12134, isoform B - - - - 10178776 567.00 0.145 0.085 -0.770518153877233 Down 0.0813630960243033 37335 4123.00 4.155 5.06 0.284288907923966 Up 0.256868313300753 rig rigor mortis K13133|1|2e-55|218|aag:AaeL_AAEL004286|gem associated protein 5 - - - 3772334 543.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 CG33928 CG33928 K09255|1|2e-35|147|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|2e-11|68.2|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 40610 2166.00 114.445 110.485 -0.0508039188431756 Down 0.155296526218465 UbcD6 ubiquitin conjugating enzyme, isoform C K10573|1|8e-85|315|dvi:Dvir_GJ10109|ubiquitin-conjugating enzyme E2 A [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle GO:0019787//small conjugating protein ligase activity GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0051297//centrosome organization;GO:0060255;GO:0006464//cellular protein modification process 43169 604.84 167.46 178.575 0.0927135910916288 Up 0.239994716682076 RpL34a ribosomal protein L34a, isoform C K02915|1|2e-58|224|dsi:Dsim_GD18147|large subunit ribosomal protein L34e GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression 32373 3655.26 8.405 10.065 0.260027447685173 Up 0.322546559239202 l(1)G0007 lethal (1) G0007, isoform B K12815|1|0.0|1049|dme:Dmel_CG32604|pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 [EC:3.6.4.13] GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0002118//aggressive behavior;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0002118//aggressive behavior;GO:0000380//alternative mRNA splicing, via spliceosome 10178929 1824.00 4.73 5.725 0.275435509644911 Up 0.266708492933562 pre-mod(mdg4)-Z pre-mod(mdg4)-Z - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 33436 883.00 0.795 0.3 -1.40599235967584 Down 0.260335490688152 CG3528 CG3528 - - - - 44125 755.00 4.33 1.51 -1.51981847540165 Down 0.548111213842293 ETH ecdysis triggering hormone - - GO:0005184//neuropeptide hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007591//molting cycle, chitin-based cuticle 41415 654.00 0.75 0.01 -6.22881869049588 Down 0.440727777043984 CG14720 CG14720 - - - - 8674076 396.00 94.91 57.09 -0.733322039563968 Down 0.685873728701625 Sfp87B seminal fluid protein 87B - - - - 246399 821.00 13.135 14.995 0.191065321735108 Up 0.302007660810989 CG30026 CG30026 - - - - 41495 1143.35 9.635 10.275 0.0927818222733241 Up 0.154735173689077 CG10038 CG10038, isoform B - - - - 39367 2325.00 5.44 5.83 0.0998892319501569 Up 0.130266807555145 CG6928 CG6928, isoform D K13962|1|4e-16|87.0|tgu:100223009|solute carrier family 26 (sulfate anion transporter), member 7 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 36426 2105.00 16.565 14.855 -0.1571895982456 Down 0.273973055078589 CG13322 CG13322, isoform C - - - - 8673990 386.00 0.56 0.995 0.829269698486045 Up 0.220380398890503 Sfp24Bc seminal fluid protein 24Bc - - - - 3346150 4401.13 4.92 6.925 0.493155755597311 Up 0.40906089023907 CG32547 CG32547, isoform D K04205|1|5e-14|80.9|dre:795311|neuropeptide Y receptor Y2;K04209|2|6e-12|73.9|nvi:100117840|neuropeptide Y receptor, invertebrate;K04206|3|5e-11|70.9|dre:30717|neuropeptide Y receptor Y4;K04314|4|7e-11|70.5|ecb:100066425|prolactin releasing hormone receptor GO:0031224//intrinsic to membrane GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0007166//cell surface receptor signaling pathway 5740553 1487.13 0.47 1.025 1.12489124782781 Up 0.263076211861049 CG34277 CG34277, isoform E - - - - 3885664 964.00 1.25 2.19 0.809002774939086 Up 0.321985206709814 CG33258 CG33258 - - GO:0030247//polysaccharide binding GO:0006022 42611 782.00 0.92 0.525 -0.80931643839089 Down 0.209549597147008 CG5391 CG5391 - - - - 31491 2943.45 23.32 21.43 -0.121935938523949 Down 0.245046889446572 CG33080 CG33080, isoform D K01187|1|1e-52|208|dme:Dmel_CG11909|alpha-glucosidase [EC:3.2.1.20];K12047|2|1e-16|89.0|rno:312272|maltase-glucoamylase [EC:3.2.1.20 3.2.1.3];K05546|4|5e-13|77.0|nve:NEMVE_v1g238696|alpha 1,3-glucosidase [EC:3.2.1.84];K12316|5|5e-12|73.6|dre:100002366|lysosomal alpha-glucosidase [EC:3.2.1.20] - - - 44014 5466.76 21.59 26.19 0.278652816328091 Up 0.437425703341699 sol small optic lobes, isoform F K08582|1|0.0|2605|dme:Dmel_CG1391|calpain-15 [EC:3.4.22.-] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0004197//cysteine-type endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004197//cysteine-type endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004197//cysteine-type endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004197//cysteine-type endopeptidase activity GO:0019538//protein metabolic process;GO:0007610//behavior;GO:0019538//protein metabolic process;GO:0007610//behavior;GO:0019538//protein metabolic process;GO:0007610//behavior;GO:0019538//protein metabolic process;GO:0007610//behavior 19835567 2540.67 9.85 6.3 -0.644771895956459 Down 0.515387663452648 49807 1213.00 18.98 21.58 0.185214872466908 Up 0.330867784968961 Spn28F serpin 28F K13963|1|0.0|707|dme:Dmel_CG8137|serpin B - GO:0004866//endopeptidase inhibitor activity - 31880 2344.00 7.345 7.06 -0.0570943072850995 Down 0.0989961695945053 Cfp1 Cfp1, isoform B K11728|1|4e-13|77.0|dre:324479|nucleosome-remodeling factor subunit BPTF - GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 19834725 1099.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 39148 2740.58 1.44 0.76 -0.921997487998727 Down 0.283350944393079 CG14168 Zasp67, isoform H K06094|1|4e-07|57.0|bfo:BRAFLDRAFT_119030|lethal giant larvae - GO:0005488//binding - 42021 1674.00 0.795 1.18 0.569760094077486 Up 0.190067362303527 CG17562 CG17562 K13356|1|1e-89|330|dwi:Dwil_GK10652|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 8674062 1426.00 0.165 0.39 1.24100809950379 Up 0.162627129837538 CG43339 CG43339, isoform C - - - - 3771927 192.00 14.29 23.265 0.703155270661431 Up 0.620096420552107 38554 1497.00 1.18 0.625 -0.916858764699754 Down 0.25706643772289 CG11350 CG11350 - - - - 36082 1809.07 9.44 12.94 0.454978852630666 Up 0.480517765156518 CG12910 CG12910, isoform C K11885|1|2e-14|81.3|cbr:CBG05428|DNA damage-inducible protein 1 - - - 37688 1181.78 8.82 15.31 0.795623721942267 Up 0.606623959846784 CG3124 CG3124, isoform B - - - - 38322 1162.00 3.565 3.365 -0.0832955718335708 Down 0.0903117157574957 CG16984 CG16984 - - - - 41067 1891.29 325.005 294.925 -0.14011379231236 Down 0.338198388588033 skap skpA associated protein, isoform H K01900|1|0.0|834|dme:Dmel_CG11963|succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center GO:0004774//succinate-CoA ligase activity;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0046605//regulation of centrosome cycle;GO:0009060//aerobic respiration;GO:0000278//mitotic cell cycle;GO:0046605//regulation of centrosome cycle;GO:0009060//aerobic respiration;GO:0000278//mitotic cell cycle;GO:0046605//regulation of centrosome cycle;GO:0009060//aerobic respiration;GO:0000278//mitotic cell cycle;GO:0046605//regulation of centrosome cycle;GO:0009060//aerobic respiration;GO:0000278//mitotic cell cycle;GO:0046605//regulation of centrosome cycle;GO:0009060//aerobic respiration;GO:0000278//mitotic cell cycle;GO:0046605//regulation of centrosome cycle;GO:0009060//aerobic respiration 40690 1014.00 31.26 59.03 0.917130563447902 Up 0.70122837141725 CG12171 CG12171 K11147|1|2e-25|116|cbr:CBG09503|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-];K00079|2|8e-25|114|cel:R11D1.11|carbonyl reductase (NADPH) [EC:1.1.1.184] - GO:0003824//catalytic activity GO:0008152//metabolic process 50225 8105.82 19.88 19.04 -0.0622842782543429 Down 0.14377228899749 Prosap prosap, isoform E K08803|1|5e-18|95.1|spu:575268|death-associated protein kinase [EC:2.7.11.1];K10380|4|9e-18|94.4|gga:396309|ankyrin - GO:0005488//binding - 32958 567.00 8.795 5.81 -0.598145414067432 Down 0.48632941487254 CG14210 CG14210, isoform B - - - - 326235 11349.00 2.235 2.67 0.256564910504236 Up 0.17365605600317 CG32702 cubilin ortholog K09608|1|3e-63|246|ecb:100061477|tolloid-like protein 1 [EC:3.4.24.-] - GO:0046872//metal ion binding - 44233 3501.34 28.955 28.985 0.00149398878475794 Up 0.0427618544445912 fray frayed, isoform G K08282|1|0.0|941|dme:Dmel_CG7693|non-specific serine/threonine protein kinase [EC:2.7.11.1];K08835|4|1e-149|531|bfo:BRAFLDRAFT_115039|oxidative-stress responsive protein 1 [EC:2.7.11.1] - GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0001885//endothelial cell development;GO:0007272;GO:0007409//axonogenesis;GO:0006464//cellular protein modification process;GO:0001885//endothelial cell development;GO:0007272;GO:0007409//axonogenesis;GO:0006464//cellular protein modification process;GO:0001885//endothelial cell development;GO:0007272;GO:0007409//axonogenesis;GO:0006464//cellular protein modification process;GO:0001885//endothelial cell development;GO:0007272;GO:0007409//axonogenesis;GO:0006464//cellular protein modification process;GO:0001885//endothelial cell development;GO:0007272;GO:0007409//axonogenesis;GO:0006464//cellular protein modification process 192535 1072.00 69.59 63.415 -0.134055875784277 Down 0.301710474177784 CG32032 CG32032 - - - - 37683 788.00 0.155 0.17 0.133266530863464 Up 0.0491348566900013 yip3 yippee interacting protein 3, isoform B K02739|1|7e-07|55.1|dwi:Dwil_GK25153|20S proteasome subunit beta 2 [EC:3.4.25.1] GO:0000502//proteasome complex;GO:0000502//proteasome complex GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0006508//proteolysis;GO:0006508//proteolysis 14462467 500.00 1.02 4.97 2.28467669959079 Up 0.624983489631489 41783 5637.70 9.42 8.89 -0.0835436407830132 Down 0.138125742966583 kibra kibra ortholog, isoform B K06112|1|1e-17|93.2|mdo:100033161|membrane-associated guanylate kinase-related - - - 41461 1395.00 7.25 7.475 0.0440925841831705 Up 0.0830141328754458 Spt3 Spt3 K11313|1|0.0|733|dme:Dmel_CG3169|transcription initiation protein SPT3 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0010468//regulation of gene expression 48552 2260.73 168.87 168.11 -0.00650750839877 Down 0.0681548012151631 Sam-S S-adenosylmethionine synthetase, isoform L K00789|1|0.0|737|dme:Dmel_CG2674|S-adenosylmethionine synthetase [EC:2.5.1.6] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046872//metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559 GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process 36138 1523.00 36.635 33 -0.15075659120626 Down 0.312343151499141 CG7222 CG7222, isoform B - - - GO:0048598//embryonic morphogenesis 33225 4653.95 3.585 3.795 0.0821267667135616 Up 0.0920618148197068 ush u-shaped, isoform E K09216|1|4e-06|55.1|dre:792456|ovo;K09229|2|5e-06|54.7|mmu:235682|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0004872//receptor activity GO:0002164//larval development;GO:0006355//regulation of transcription, DNA-dependent;GO:0048534;GO:0001708//cell fate specification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0042688//crystal cell differentiation;GO:0035028;GO:0001894//tissue homeostasis 38749 901.99 17.22 16.34 -0.0756771592511604 Down 0.163650772685246 CG8549 CG8549, isoform B - - - - 31652 846.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 nullo nullo - - - - 31416 1594.00 0.335 0.56 0.741265731599832 Up 0.151730286619997 CG12681 CG12681 - - - - 40695 1220.05 145.215 131.86 -0.139183497907408 Down 0.331528199709417 elm ethanol sensitive with low memory, isoform B K06268|1|5e-104|377|dya:Dyak_GE24150|protein phosphatase 3, regulatory subunit - GO:0046872//metal ion binding - 4379817 4820.72 1.595 1.73 0.117215613871855 Up 0.0851935015189539 RunxA RunxA, isoform D K09280|1|1e-63|244|dme:Dmel_CG42267|runt-related transcription factor, other;K08367|4|5e-56|219|gga:396152|runt-related transcription factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032559 GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 3772287 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 14462838 556.00 0.08 0.345 2.10852445677817 Up 0.192676000528332 CG43880 CG43880 - - - - 34380 2056.37 32.015 33.02 0.0445921102878138 Up 0.122837141725003 CYLD cylindromatosis ortholog, isoform E K08601|1|0.0|1062|dme:Dmel_CG5603|ubiquitin thioesterase CYLD [EC:3.1.2.15] GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex GO:0016790//thiolester hydrolase activity;GO:0015631//tubulin binding;GO:0019783//small conjugating protein-specific protease activity;GO:0005198//structural molecule activity;GO:0016790//thiolester hydrolase activity;GO:0015631//tubulin binding;GO:0019783//small conjugating protein-specific protease activity;GO:0005198//structural molecule activity;GO:0016790//thiolester hydrolase activity;GO:0015631//tubulin binding;GO:0019783//small conjugating protein-specific protease activity;GO:0005198//structural molecule activity GO:0006952//defense response;GO:0019941//modification-dependent protein catabolic process;GO:0055088//lipid homeostasis;GO:0010467//gene expression;GO:0070646//protein modification by small protein removal;GO:0006952//defense response;GO:0019941//modification-dependent protein catabolic process;GO:0055088//lipid homeostasis;GO:0010467//gene expression;GO:0070646//protein modification by small protein removal;GO:0006952//defense response;GO:0019941//modification-dependent protein catabolic process;GO:0055088//lipid homeostasis;GO:0010467//gene expression;GO:0070646//protein modification by small protein removal 53515 3778.09 5.75 7.105 0.305272693411043 Up 0.31765949015982 Myo28B1 myosin 28B1, isoform D K10359|1|0.0|955|ame:726683|myosin VII GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0016887//ATPase activity;GO:0008092//cytoskeletal protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0008092//cytoskeletal protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0008092//cytoskeletal protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0008092//cytoskeletal protein binding;GO:0032559 - 40877 813.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 CG10032 CG10032 K06233|1|9e-12|70.5|bta:533181|low density lipoprotein-related protein 2 - - - 31079 2330.93 26.205 24.195 -0.115133169761117 Down 0.248084797252675 CG11412 CG11412, isoform D K00670|1|4e-171|602|dme:Dmel_CG11412|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - - - 40870 2572.00 5.08 5.48 0.109347396188361 Up 0.135484084004755 CG1234 CG1234 - - - - 19835352 1178.00 5.335 2.245 -1.24877282608328 Down 0.54854048342359 36819 1495.00 31.6 32.215 0.0278080363569655 Up 0.0998547087570995 JhI-26 juvenile hormone-inducible protein 26 - - - - 40477 758.00 0.42 1.045 1.31504170930212 Up 0.288799366001849 CG6914 CG6914 K03951|1|2e-73|275|dme:Dmel_CG6914|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 7 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain 45922 2610.00 16.91 18.565 0.134708655444757 Up 0.247094175141989 rap retina aberrant in pattern, isoform B K03364|1|0.0|987|dme:Dmel_CG3000|cell division cycle 20-like protein 1, cofactor of APC complex GO:0043234//protein complex;GO:0005813//centrosome;GO:0043234//protein complex;GO:0005813//centrosome GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0016477//cell migration;GO:0048592//eye morphogenesis;GO:0030154//cell differentiation;GO:0009057//macromolecule catabolic process;GO:0007096//regulation of exit from mitosis;GO:0007560//imaginal disc morphogenesis;GO:0006464//cellular protein modification process;GO:0016477//cell migration;GO:0048592//eye morphogenesis;GO:0030154//cell differentiation;GO:0009057//macromolecule catabolic process;GO:0007096//regulation of exit from mitosis;GO:0007560//imaginal disc morphogenesis;GO:0006464//cellular protein modification process 42130 10186.54 18.11 20.34 0.167533132907332 Up 0.302569013340378 osa osa, isoform F K11653|1|0.0|1435|dme:Dmel_CG7467|AT-rich interactive domain-containing protein 1 GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0006355//regulation of transcription, DNA-dependent;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007478//leg disc morphogenesis;GO:0030182//neuron differentiation;GO:0007173//epidermal growth factor receptor signaling pathway 43304 2033.38 0.015 0.27 4.16992500144231 Up 0.23609826971338 Cyp6a18 Cyp6a18, isoform B K00517|1|0.0|1019|dme:Dmel_CG13977| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 39691 1548.91 38.12 33.385 -0.191348079016962 Down 0.367025492008982 CG7656 CG7656, isoform F K02207|1|6e-115|414|dme:Dmel_CG7656|ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process 10178839 573.00 0.355 0.4 0.17218097538268 Up 0.0647866860388324 CG42690 CG42690 - - - - 41631 863.00 2.875 1.065 -1.4327085256059 Down 0.469290714568749 CG15887 CG15887 - - - - 38130 492.00 0.01 0.38 5.24792751344359 Up 0.310130762118611 LysS lysozyme S K01185|1|6e-73|272|dme:Dmel_CG1165|lysozyme [EC:3.2.1.17];K13915|3|2e-61|234|dwi:Dwil_GK12154|lysozyme C [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 36851 627.12 1057.58 982.475 -0.106274197048229 Down 0.287181349887729 RpS15 ribosomal protein S15, isoform B K02958|1|6e-61|233|dya:Dyak_GE14054|small subunit ribosomal protein S15e - - - 40839 1098.00 2.485 3.16 0.346678706614817 Up 0.236428477083609 djl don juan like - GO:0019861//flagellum;GO:0005739//mitochondrion - GO:0022414//reproductive process 38701 2321.00 36.605 11.515 -1.66852631340385 Down 0.744914806498481 l(3)mbn lethal (3) malignant blood neoplasm - GO:0044424//intracellular part GO:0042302//structural constituent of cuticle GO:0042386//hemocyte differentiation 34297 1350.00 0.875 3.64 2.05658352836637 Up 0.565612204464404 CG17633 CG17633 K01290|1|8e-82|304|dvi:Dvir_GJ16227|carboxypeptidase A, invertebrate [EC:3.4.17.-] GO:0044421//extracellular region part GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 40341 1732.00 0.33 0.9 1.44745897697122 Up 0.279454497424382 CG10510 CG10510 - - - - 32321 5914.90 18.29 20.255 0.14722300993772 Up 0.276680755514463 NFAT NFAT homolog, isoform H K04446|1|0.0|664|dse:Dsec_GM17623|nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0045449;GO:0006970//response to osmotic stress;GO:0006351//transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent;GO:0006970//response to osmotic stress;GO:0006355//regulation of transcription, DNA-dependent;GO:0006970//response to osmotic stress;GO:0006355//regulation of transcription, DNA-dependent;GO:0006970//response to osmotic stress;GO:0006355//regulation of transcription, DNA-dependent;GO:0006970//response to osmotic stress 19835694 3542.00 0.16 0.12 -0.415037499278844 Down 0.0678576145819575 40943 1974.00 94.925 57.74 -0.717216986270469 Down 0.683958525954299 CG2781 CG2781 K10250|1|5e-71|269|dre:327274|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane - - 34156 3153.00 16.88 13.385 -0.334697765066407 Down 0.441817461365738 Aats-ala Alanyl-tRNA synthetase, isoform B K01872|1|0.0|1904|dme:Dmel_CG13391|alanyl-tRNA synthetase [EC:6.1.1.7] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0003723//RNA binding;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0003723//RNA binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 318970 762.00 1.01 1.495 0.56579019144631 Up 0.217771760665698 CG31832 CG31832 K10104|1|2e-33|141|cqu:CpipJ_CPIJ000937|ficolin;K06252|3|2e-31|135|hsa:63923|tenascin GO:0044421//extracellular region part GO:0005515//protein binding GO:0023060 40319 3540.49 0.675 0.955 0.500613230984918 Up 0.158301413287545 CG12983 CG12983, isoform F - - - - 19835390 1394.00 11.95 13.165 0.139696903177952 Up 0.232895258222164 37772 6361.00 12.82 16.665 0.378425055491507 Up 0.471073834367983 CG5549 CG5549 K03308|1|0.0|1509|dme:Dmel_CG5549|neurotransmitter:Na+ symporter, NSS family GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport 40065 2312.00 0.695 0.735 0.0807312721128568 Up 0.0531303658697662 Ir75d ionotropic receptor 75d K12855|1|1e-37|158|dsi:Dsim_GD14782|pre-mRNA-processing factor 6 GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 42928 5117.47 13.835 18.295 0.403126771729133 Up 0.491579712059173 CG5789 CG5789, isoform B K05673|1|0.0|948|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|3|0.0|911|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 43673 3965.43 37.7 36.165 -0.0599703718323442 Down 0.161471404041738 dco discs overgrown, isoform D K02218|1|2e-177|623|dme:Dmel_CG2048|casein kinase 1 [EC:2.7.11.1];K08960|3|2e-156|553|gga:378891|casein kinase 1, epsilon [EC:2.7.11.1] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0007166//cell surface receptor signaling pathway;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007444//imaginal disc development;GO:0030534//adult behavior;GO:0001736//establishment of planar polarity;GO:0044060//regulation of endocrine process;GO:0006915//apoptotic process;GO:0031331;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007166//cell surface receptor signaling pathway;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007444//imaginal disc development;GO:0030534//adult behavior;GO:0001736//establishment of planar polarity;GO:0044060//regulation of endocrine process;GO:0006915//apoptotic process;GO:0031331;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0007562//eclosion;GO:0006606//protein import into nucleus;GO:0007166//cell surface receptor signaling pathway;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007444//imaginal disc development;GO:0030534//adult behavior;GO:0001736//establishment of planar polarity;GO:0044060//regulation of endocrine process;GO:0006915//apoptotic process;GO:0031331;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0007562//eclosion;GO:0006606//protein import into nucleus 36629 1177.00 10.07 18.23 0.85625087803235 Up 0.632215031039493 CG12860 CG12860 - - - - 53508 1595.00 0.345 2.995 3.11788773601062 Up 0.590873068286884 Ugt86Dc Ugt86Dc K00699|1|9e-152|536|dpo:Dpse_GA19758|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 192611 990.00 1.975 3.61 0.870146183822706 Up 0.41890106987188 CG32388 CG32388 - - - - 39926 843.00 0.56 0.785 0.487265826834023 Up 0.138819178444063 CG6485 CG6485 K00329|1|3e-137|487|dme:Dmel_CG6485|NADH dehydrogenase [EC:1.6.5.3];K00356|1|3e-137|487|dme:Dmel_CG6485|NADH dehydrogenase [EC:1.6.99.3];K03943|2|2e-69|261|dvi:Dvir_GJ13038|NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity;GO:0000166//nucleotide binding GO:0022904//respiratory electron transport chain 32814 1426.44 4.945 4.165 -0.247654025393563 Down 0.230253599260335 CG6023 CG6023, isoform C - - - - 39036 1671.00 0.185 0.24 0.375509135092206 Up 0.0729758288204993 Doc3 Dorsocross3 K10180|1|5e-110|395|dpo:Dpse_GA18682|T-box protein 6;K10177|4|3e-65|249|oaa:100078876|T-box protein 3;K10176|5|4e-65|249|xtr:619588|T-box protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009792//embryo development ending in birth or egg hatching;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007507//heart development 3772461 297.00 0.01 0.21 4.39231742277876 Up 0.216153744551578 10178915 1374.00 0.83 0.44 -0.915607812709627 Down 0.213082816008453 31427 797.00 0.17 0.06 -1.50250034052918 Down 0.115770704002113 CG12680 CG12680, isoform C - - - - 34829 4029.00 6.8 9.135 0.425869982489787 Up 0.420981376304319 CG17341 CG17341 - - - - 42314 5243.00 1.865 2.255 0.273951803000143 Up 0.165565975432572 Ino80 Ino80 K11665|1|0.0|2765|dme:Dmel_CG31212|DNA helicase INO80 [EC:3.6.1.-] - GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0032559 - 39916 985.36 8.57 12.16 0.504776119331086 Up 0.49432043323207 TpnC73F troponin C at 73F, isoform C K02183|1|1e-23|110|spu:585061|calmodulin - GO:0046872//metal ion binding - 40944 934.13 6.655 9.93 0.577355051616482 Up 0.496896050719852 CG14463 CG14463, isoform B K03858|1|4e-116|417|dme:Dmel_CG14463|phosphatidylinositol glycan, class H - - - 35184 2670.67 5.85 6.29 0.104623392408522 Up 0.13716814159292 Lim3 Lim3, isoform G K09374|1|0.0|753|dse:Dsec_GM17030|LIM homeobox protein 3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007411//axon guidance;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007411//axon guidance;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 3772569 1443.30 0.17 0.09 -0.917537839808027 Down 0.0946374323074891 CG32269 CG32269, isoform B K01312|1|3e-41|170|dme:Dmel_CG18211|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31988 4696.00 1.945 2.325 0.257460561009202 Up 0.16137234183067 Hmr hybrid male rescue K10955|1|4e-06|55.1|tgu:100220116|intestinal mucin-2 - GO:0001071//nucleic acid binding transcription factor activity - 41406 892.65 43.94 47.315 0.106762755557846 Up 0.256339981508387 Taf12 TBP-associated factor 12, isoform E K03126|1|2e-50|199|dme:Dmel_CG17358|transcription initiation factor TFIID subunit D10 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 42976 2038.00 13.395 6.28 -1.09285811695075 Down 0.640734381191388 CG11069 CG11069 K05683|1|0.0|1120|dpo:Dpse_GA10739|ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1) GO:0043234//protein complex;GO:0044464//cell part GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 59145 1687.00 0.445 0.36 -0.305808429524085 Down 0.0872077664773478 CG18754 CG18754, isoform C K01362|1|3e-51|202|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|3e-31|135|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process 19835813 1217.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 19835824 688.00 0.01 0.64 6 Up 0.408268392550522 36013 1067.00 2.51 2.845 0.18074128835581 Up 0.141295733720777 Lsm11 Lsm11 - GO:0044451//nucleoplasm part;GO:0030532//small nuclear ribonucleoprotein complex - GO:0008334//histone mRNA metabolic process;GO:0006396//RNA processing 31458 4419.48 9.84 10.27 0.0617059609789552 Up 0.11689340906089 CG4165 CG4165, isoform F K11844|1|0.0|1596|dme:Dmel_CG4165|ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.1.2.15] - GO:0008233//peptidase activity;GO:0046872//metal ion binding;GO:0008233//peptidase activity;GO:0046872//metal ion binding;GO:0008233//peptidase activity;GO:0046872//metal ion binding;GO:0008233//peptidase activity;GO:0046872//metal ion binding - 34725 718.00 0.17 0.08 -1.08746284125034 Down 0.103057720248316 CG16815 CG16815 - - - - 38612 1387.41 367.7 383.45 0.0605092930909134 Up 0.183199049002774 CG4769 CG4769, isoform B K00413|1|5e-158|557|dsi:Dsim_GD13884|ubiquinol-cytochrome c reductase cytochrome c1 subunit [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain GO:0005506//iron ion binding GO:0022904//respiratory electron transport chain 31801 4043.00 1.545 0.92 -0.747901071847362 Down 0.260335490688152 Caf1-180 Caf1-180 K10750|1|0.0|875|dme:Dmel_CG12109|chromatin assembly factor 1 subunit A GO:0043234//protein complex - GO:0034728//nucleosome organization 40294 1249.00 20.805 26.56 0.352324858302166 Up 0.496499801875578 Pex14 peroxin 14 K13343|1|3e-134|478|dme:Dmel_CG4289|peroxin-14 GO:0044439 - - 38993 1547.00 5329.9 7695.14 0.529839108896349 Up 0.659886408664641 Arr2 arrestin 2 K13805|1|0.0|749|dme:Dmel_CG5962|arrestin-2 GO:0005626//insoluble fraction;GO:0042995//cell projection;GO:0044424//intracellular part GO:0002046//opsin binding GO:0016059//deactivation of rhodopsin mediated signaling;GO:0043954//cellular component maintenance 5740115 338.59 30.875 36.74 0.250912489751947 Up 0.429863954563466 CG34250 CG34250, isoform B - - - - 40851 1532.00 39.745 40.725 0.035141320842358 Up 0.122440892880729 CG10098 CG10098 - - - GO:0008152//metabolic process 43506 2043.00 13.43 11.7 -0.198950774956676 Down 0.300521727644961 IntS11 integrator 11 K13148|1|0.0|1192|dme:Dmel_CG1972|integrator complex subunit 11 [EC:3.1.27.-] GO:0005849//mRNA cleavage factor complex GO:0003824//catalytic activity GO:0008380//RNA splicing;GO:0031124//mRNA 3'-end processing 19834865 1097.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 33835 1705.78 794.81 656.54 -0.275727113495745 Down 0.51865671641791 eIF-4a eukaryotic initiation factor 4a, isoform F K03257|1|0.0|772|dme:Dmel_CG9075|translation initiation factor eIF-4A GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032559;GO:0008135//translation factor activity, nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559;GO:0008135//translation factor activity, nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559;GO:0008135//translation factor activity, nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559;GO:0008135//translation factor activity, nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity GO:0006261//DNA-dependent DNA replication;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0002164//larval development;GO:0007052//mitotic spindle organization;GO:0042078//germ-line stem cell division;GO:0019827//stem cell maintenance;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006261//DNA-dependent DNA replication;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0002164//larval development;GO:0007052//mitotic spindle organization;GO:0042078//germ-line stem cell division;GO:0019827//stem cell maintenance;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006261//DNA-dependent DNA replication;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0002164//larval development;GO:0007052//mitotic spindle organization;GO:0042078//germ-line stem cell division;GO:0019827//stem cell maintenance;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006261//DNA-dependent DNA replication;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0002164//larval development;GO:0007052//mitotic spindle organization;GO:0042078//germ-line stem cell division;GO:0019827//stem cell maintenance;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0000380//alternative mRNA splicing, via spliceosome 5740593 386.07 274.54 299.12 0.123708013608416 Up 0.301380266807555 CG34439 CG34439, isoform B K05129|1|4e-27|121|dwi:Dwil_GK21680|muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 43741 3005.56 28.315 24.535 -0.206725258419354 Down 0.372242768458592 CG1910 CG1910, isoform D - - - - 40438 3067.00 1.525 1.685 0.14393934873161 Up 0.094208162726192 DNApol-eta DNApol-eta K03509|1|0.0|1538|dme:Dmel_CG7143|DNA polymerase eta subunit [EC:2.7.7.7] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0034061 GO:0006301//postreplication repair 48311 4057.59 52.395 80.365 0.61713818232462 Up 0.65813630960243 Pkc53E protein C kinase 53E, isoform F K02677|1|0.0|1392|der:Dere_GG20645|classical protein kinase C [EC:2.7.11.13] - GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0004697//protein kinase C activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0004697//protein kinase C activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0004697//protein kinase C activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023033 39476 594.00 110.85 120.89 0.125086139831859 Up 0.311781798969753 CG11267 CG11267 K04078|1|1e-46|185|dme:Dmel_CG11267|chaperonin GroES GO:0031980 GO:0032559 GO:0006457//protein folding;GO:0050896//response to stimulus 5740413 867.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 CG34295 CG34295 - - - - 39133 1393.48 46.22 44.66 -0.0495340086451576 Down 0.145291242900542 UbcD4 ubiquitin conjugating enzyme 4, isoform C K04649|1|5e-105|381|dya:Dyak_GE20867|ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process 318883 1108.00 1.12 1.005 -0.156303230878676 Down 0.0861841236296394 Tengl1 testis EndoG-Like 1 K01173|1|3e-22|105|aag:AaeL_AAEL002064|endonuclease [EC:3.1.30.-] - GO:0004519//endonuclease activity;GO:0043169//cation binding - 39456 992.00 13.885 14.655 0.0778657908706957 Up 0.157773081495179 CG10754 CG10754 K12826|1|3e-124|444|dme:Dmel_CG10754|splicing factor 3A subunit 2 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0046914//transition metal ion binding GO:0000278//mitotic cell cycle;GO:0000377 39113 342.00 0.695 0.15 -2.21205047711499 Down 0.289327697794215 CG14177 CG14177 - - - - 19834769 821.00 0.245 0.06 -2.02974734339405 Down 0.162495046889447 39999 6053.20 33.515 39.88 0.25085847589144 Up 0.434387795535596 Eip75B Ecdysone-induced protein 75B, isoform F K08701|1|0.0|1112|dya:Dyak_GE22099|nuclear receptor subfamily 1 group D member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005506//iron ion binding;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005506//iron ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005506//iron ion binding;GO:0003677//DNA binding;GO:0005506//iron ion binding;GO:0004872//receptor activity GO:0006351//transcription, DNA-dependent;GO:0010565//regulation of cellular ketone metabolic process;GO:0006959//humoral immune response;GO:0007591//molting cycle, chitin-based cuticle;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0006351//transcription, DNA-dependent;GO:0010565//regulation of cellular ketone metabolic process;GO:0006959//humoral immune response;GO:0007591//molting cycle, chitin-based cuticle;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0006351//transcription, DNA-dependent;GO:0010565//regulation of cellular ketone metabolic process;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0007591//molting cycle, chitin-based cuticle;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0010565//regulation of cellular ketone metabolic process;GO:0002165//instar larval or pupal development;GO:0006959//humoral immune response;GO:0007591//molting cycle, chitin-based cuticle;GO:0006350 318245 730.00 1.37 1.615 0.237358271733398 Up 0.123233390569278 CG32847 CG32847 K10666|1|7e-40|163|dpe:Dper_GL22918|E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 39010 1061.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 CG13312 CG13312 - - - - 33254 1732.00 4.875 5.09 0.0622634374387222 Up 0.088033284902919 KH1 DEAD box protein 21E2 K13982|1|3e-37|156|nvi:100120300|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13] - GO:0042623//ATPase activity, coupled;GO:0032559 GO:0006726//eye pigment biosynthetic process 31069 1744.00 0.05 0.105 1.0703893278914 Up 0.0856557918372738 CG11382 CG11382, isoform C - - - - 37702 5084.00 23.12 21.63 -0.0961077325387001 Down 0.210011887465328 CG3493 Golgin-245 ortholog K10352|1|3e-41|171|cqu:CpipJ_CPIJ015899|myosin heavy chain - - - 36253 1650.02 17.745 18.62 0.0694404984978491 Up 0.154107779685643 CG13197 CG13197, isoform B K01104|1|0.0|688|dme:Dmel_CG13197|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process 43469 6226.77 26.945 30.74 0.190099578301025 Up 0.355600316999075 Ptp99A protein tyrosine phosphatase 99A, isoform G K01104|1|0.0|1334|dpo:Dpse_GA15180|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043005//neuron projection;GO:0016020//membrane;GO:0043005//neuron projection;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044424//intracellular part;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044424//intracellular part;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044424//intracellular part;GO:0016020//membrane GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008170//N-methyltransferase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008170//N-methyltransferase activity;GO:0004725//protein tyrosine phosphatase activity GO:0007411//axon guidance;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0031167//rRNA methylation;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0031167//rRNA methylation;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0031167//rRNA methylation;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 46091 5334.00 5.705 6.4 0.165845018598681 Up 0.198982961299696 Nup214 nucleoporin 214kD - - - - 33602 3441.90 9.155 7.415 -0.304113193342707 Down 0.346453572843746 bowl brother of odd with entrails limited, isoform H K09215|1|0.0|835|dme:Dmel_CG10021|odd-skipped GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0007480//imaginal disc-derived leg morphogenesis;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0007480//imaginal disc-derived leg morphogenesis 12798476 781.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 CG43203 CG43203 - - - - 40375 1308.00 0.335 0.435 0.376854305390956 Up 0.093778893144895 Neu2 Neuroectoderm-expressed 2, isoform B K09228|1|8e-53|207|mmu:380850|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 43113 923.00 0.425 0.845 0.991488500144483 Up 0.22219653942676 CG17195 CG17195 - - GO:0046914//transition metal ion binding - 19836031 579.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 42423 1331.59 1.92 1.91 -0.00753367268540755 Down 0.041044776119403 Dic2 dicarboxylate carrier 2, isoform C K13577|1|5e-81|301|dpe:Dper_GL24469|mitochondrial dicarboxylate carrier GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport 31389 2246.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG3546 CG3546 - - - - 33895 2562.03 3.565 4.195 0.234768733995935 Up 0.20330867784969 CG13982 CG13982, isoform B - - - - 42731 1291.00 0.98 0.825 -0.248387629869392 Down 0.103321886144499 CG6733 CG6733 K01436|1|0.0|809|dme:Dmel_CG6733|aminoacylase [EC:3.5.1.14] GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding GO:0006519 44496 2329.00 13.915 11.86 -0.230536898785604 Down 0.333014132875446 Uba2 Smt3 activating enzyme 2 K10685|1|0.0|1185|dme:Dmel_CG7528|ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0008641//small protein activating enzyme activity;GO:0032559 GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process 41806 672.00 0.125 0.4 1.67807190511264 Up 0.195713908334434 VhaPPA1-2 vacuolar H[+] ATPase PPA1 subunit 2 K03661|1|6e-97|352|dme:Dmel_CG7026|V-type H+-transporting ATPase 21kDa proteolipid subunit [EC:3.6.3.14] - - - 19836190 833.00 5.45 1.705 -1.67648449064012 Down 0.597642319376569 39900 4105.94 70.44 49.31 -0.514514656330089 Down 0.62395984678378 Exn ephexin, isoform E K07525|1|0.0|1711|dme:Dmel_CG3799|neuronal guanine nucleotide exchange factor GO:0030532//small nuclear ribonucleoprotein complex;GO:0045202//synapse;GO:0016020//membrane;GO:0030532//small nuclear ribonucleoprotein complex;GO:0045202//synapse;GO:0016020//membrane;GO:0030532//small nuclear ribonucleoprotein complex;GO:0045202//synapse;GO:0016020//membrane;GO:0030532//small nuclear ribonucleoprotein complex;GO:0045202//synapse;GO:0016020//membrane;GO:0030532//small nuclear ribonucleoprotein complex;GO:0045202//synapse;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0050804//regulation of synaptic transmission;GO:0007266//Rho protein signal transduction;GO:0050804//regulation of synaptic transmission;GO:0007266//Rho protein signal transduction;GO:0050804//regulation of synaptic transmission;GO:0007266//Rho protein signal transduction;GO:0050804//regulation of synaptic transmission;GO:0007266//Rho protein signal transduction;GO:0050804//regulation of synaptic transmission;GO:0007266//Rho protein signal transduction 30995 1955.24 131.595 119.905 -0.134212854463995 Down 0.313564918768987 CG17896 CG17896, isoform B K00140|1|0.0|999|dme:Dmel_CG17896|methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.27] - - - 36609 4868.67 0.59 0.87 0.560300446486887 Up 0.160414740457007 Oaz O/E-associated zinc finger protein, isoform C K09228|1|1e-28|129|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 36878 887.04 176.15 189.68 0.106763093099682 Up 0.280048870690794 Sod2 superoxide dismutase 2 (Mn), isoform B K04564|1|2e-117|421|dme:Dmel_CG8905|superoxide dismutase, Fe-Mn family [EC:1.15.1.1] - - - 41889 1474.00 242.36 364.76 0.589795919906105 Up 0.672830537577599 Rh6 rhodopsin 6 K13802|1|3e-58|226|dvi:Dvir_GJ10183|opsin Rh1 - - - 36669 2358.18 17.28 18.325 0.0847099808577059 Up 0.172698454629507 CG10253 CG10253, isoform D K00803|1|0.0|1266|dme:Dmel_CG10253|alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26] GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody GO:0030554//adenyl nucleotide binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0030554//adenyl nucleotide binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0030554//adenyl nucleotide binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0030554//adenyl nucleotide binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups - 37532 2392.00 11.615 9.82 -0.242194224494115 Down 0.323537181349888 CG6758 CG6758 K10317|1|0.0|1149|dme:Dmel_CG6758|F-box protein 42 - GO:0005488//binding - 38697 1544.00 12.29 12.48 0.0221330184895868 Up 0.0688152159556201 CG10467 CG10467 K01785|1|0.0|750|dme:Dmel_CG10467|aldose 1-epimerase [EC:5.1.3.3] - GO:0005488//binding;GO:0003824//catalytic activity GO:0005996//monosaccharide metabolic process 39094 1028.00 4.78 3.055 -0.645838238162019 Down 0.406155065381059 CG3448 CG3448 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006281//DNA repair 50143 662.00 0.555 1.52 1.45351164709348 Up 0.359760929863955 e(y)2b enhancer of yellow 2b, isoform B K11368|1|6e-14|76.6|smm:Smp_038300|enhancer of yellow 2 transcription factor GO:0044427//chromosomal part;GO:0070461//SAGA-type complex;GO:0005635//nuclear envelope GO:0030528//transcription regulator activity;GO:0019904//protein domain specific binding;GO:0031490//chromatin DNA binding GO:0006406//mRNA export from nucleus;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006342//chromatin silencing 35756 3592.23 12.685 11.75 -0.110462762611577 Down 0.191091005151235 nito spenito, isoform C K13190|1|0.0|1303|dme:Dmel_CG2910|RNA-binding protein 15 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0005488//binding;GO:0005488//binding GO:0010468//regulation of gene expression;GO:0000377;GO:0010468//regulation of gene expression;GO:0000377 42244 2394.00 5.42 5.41 -0.00266425752705627 Down 0.0401862369568089 CG7706 CG7706 K13108|1|6e-09|63.2|cel:C32E8.5|smad nuclear-interacting protein 1 - - - 10178908 282.00 3.66 27.31 2.89951376048124 Up 0.786454893673227 CG42782 CG42782 - - - - 38399 9555.02 16.53 18.685 0.176793839088431 Up 0.307158895786554 CG11505 CG11505, isoform D K11090|1|8e-09|63.5|dre:321504|lupus La protein - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 37593 581.83 8.24 11.79 0.516847475796544 Up 0.496598864086646 CG3746 CG3746, isoform B - - - - 31665 3194.00 5.03 3.9 -0.367084276055916 Down 0.305177651565183 brk brinker - - - - 19835210 303.00 1.34 1.29 -0.0548619350345183 Down 0.0546493197728173 34650 1413.00 0.97 1.5 0.628905848308753 Up 0.229890371153084 CG17010 CG17010 K00852|1|0.0|786|dme:Dmel_CG17010|ribokinase [EC:2.7.1.15] - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding - 37970 1615.00 4.815 4.215 -0.192003166901377 Down 0.189671113459252 Orc4 origin recognition complex subunit 4 K02606|1|0.0|830|dme:Dmel_CG2917|origin recognition complex subunit 4 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0006259//DNA metabolic process 19834963 1400.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 12798437 665.00 8.22 15.465 0.911796534407582 Up 0.627757231541408 CG43219 CG43219 - - - - 31523 2839.85 8.45 8.74 0.048681938331052 Up 0.0960903447364945 CG12236 CG12236, isoform B K02174|1|2e-31|137|dme:Dmel_CG11491|broad;K09237|2|2e-27|124|aga:AgaP_AGAP003537|Cys2His2 zinc finger developmental/cell cycle regulator, other - - - 35957 8117.00 16.165 13.595 -0.249797356101325 Down 0.366596222427685 CG13739 CG13739 - - - - 42687 6186.23 15.07 16.175 0.102086295282046 Up 0.194260995905429 wge winged eye, isoform F - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 36360 2048.00 5.945 5.705 -0.0594499234569743 Down 0.0920948355567296 Nup54 nucleoporin 54kD - - - - 42780 2212.00 0.055 0.065 0.241008099503795 Up 0.0461960110949676 CG10182 CG10182 K00680|1|0.0|783|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 44111 5158.21 6.42 6.03 -0.0904152952222183 Down 0.126403381323471 slpr slipper, isoform D K04418|1|2e-131|471|dre:560932|mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25];K04417|2|3e-130|467|mmu:338372|mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 34756 2077.35 1.27 1.825 0.523067966995214 Up 0.230022454101176 CG10859 CG10859, isoform B K11143|1|2e-85|317|aga:AgaP_AGAP011539|dynein intermediate chain 2, axonemal GO:0030286//dynein complex GO:0016887//ATPase activity GO:0007017//microtubule-based process 41855 1806.00 17.2 18.71 0.121400993651324 Up 0.230947034737815 CG6276 CG6276 - - - - 41059 955.00 268.26 223.075 -0.266103111807691 Down 0.501915202747325 CG9836 CG9836 K04488|1|4e-57|221|xtr:394688|nitrogen fixation protein NifU and related proteins - GO:0046914//transition metal ion binding;GO:0051540 GO:0031163 43507 1189.83 557.735 535.975 -0.0574140992065266 Down 0.184189671113459 ATPsyn-gamma ATP synthase-gamma chain, isoform C K02136|1|2e-161|568|dme:Dmel_CG7610|F-type H+-transporting ATPase subunit gamma [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0006909//phagocytosis;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006909//phagocytosis;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006909//phagocytosis;GO:0006754//ATP biosynthetic process 42904 4394.60 27.185 29.34 0.110058042875288 Up 0.239499405626734 CG6454 CG6454, isoform E K02677|1|5e-06|54.3|aga:AgaP_AGAP012252|classical protein kinase C [EC:2.7.11.13] - - - 43294 2360.00 50.125 45.745 -0.131916268376607 Down 0.293422269185048 Hmu hemomucin K01774|1|0.0|827|dme:Dmel_CG3373| [EC:4.-.-.-];K01757|3|2e-128|460|dme:Dmel_CG11833|strictosidine synthase [EC:4.3.3.2] GO:0044444//cytoplasmic part GO:0016843;GO:0003723//RNA binding;GO:0004871//signal transducer activity;GO:0004175//endopeptidase activity GO:0008152//metabolic process 4379884 535.00 39.465 44.265 0.165592672266118 Up 0.346519614317792 CG34132 CG34132 K10836|1|3e-33|139|dme:Dmel_CG11611|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 31290 4970.85 3.82 3.155 -0.2759326330532 Down 0.219686963413023 rst roughest, isoform B K12567|1|2e-17|92.4|rno:84015|titin [EC:2.7.11.1] - - - 33755 1709.00 9.46 5.495 -0.783720702390164 Down 0.548474441949544 Cyp4ac2 Cyp4ac2 K00517|1|0.0|1026|dme:Dmel_CG17970| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0009407//toxin catabolic process 32719 712.00 0.06 0.065 0.115477217419936 Up 0.0441487253995509 CG8664 CG8664, isoform B - - - - 37057 1595.00 0.37 0.36 -0.0395283641866375 Down 0.0418702945449742 Muc55B mucin 55B, isoform B K01323|1|1e-13|78.2|mcc:702117|coagulation factor XI [EC:3.4.21.27] - - - 37911 837.00 1.26 1.41 0.162271428898877 Up 0.0933166028265751 CG13581 CG13581 - - - - 40560 2301.15 15.14 17.315 0.193657182211497 Up 0.315942411834632 CG32944 CG32944, isoform G K08793|1|0.0|845|dme:Dmel_CG32944|serine/threonine kinase 32 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 59239 1378.00 3.395 3.085 -0.138141085095314 Down 0.127988376700568 CG18764 CG18764 K09228|1|4e-33|142|mmu:237411|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 41718 2386.73 22.07 20.14 -0.132022946272829 Down 0.257693831726324 Abi abelson interacting protein, isoform F K05751|1|3e-75|283|dre:692331|abl interactor 2 - - - 38838 956.00 0.085 0.095 0.160464672193246 Up 0.045238409721305 CG8541 CG8541 - - - - 41101 908.00 0.215 0.15 -0.51937415909358 Down 0.0840047549861313 CG16736 CG16736 K13577|1|2e-19|95.9|bfo:BRAFLDRAFT_271717|mitochondrial dicarboxylate carrier GO:0031967;GO:0031224//intrinsic to membrane - GO:0006810//transport 2768999 1502.68 10.445 11.025 0.0779661633777745 Up 0.142748646149782 CG42676 CG42676, isoform F - - - - 39930 1853.14 4.09 4.57 0.160093322116321 Up 0.163386606789064 CG6479 CG6479, isoform C - - - - 40806 792.00 1.39 1.11 -0.324525206373402 Down 0.147668735966187 CG31482 CG31482 - - - - 33398 1284.81 5.075 5.78 0.18766167042814 Up 0.204926693963809 CG10880 CG10880, isoform B - - - - 3772247 1876.10 5.785 6.46 0.159217205586435 Up 0.191190067362304 CG33671 CG33671, isoform B K00869|1|0.0|725|dme:Dmel_CG33671|mevalonate kinase [EC:2.7.1.36] GO:0044424//intracellular part GO:0016301//kinase activity;GO:0032559 GO:0006720//isoprenoid metabolic process;GO:0006796//phosphate-containing compound metabolic process 5740612 1172.00 0.075 0.04 -0.906890595608519 Down 0.0698718795403513 CG34451 CG34451, isoform C K00731|1|8e-34|144|dgr:Dgri_GH25082|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] - - - 32599 689.31 64.915 74.94 0.20718409535665 Up 0.416952846387531 CG9921 CG9921, isoform C - - - - 41942 3829.54 16.885 17.975 0.0902495913191838 Up 0.184024567428345 mor moira, isoform B K11649|1|0.0|1696|dme:Dmel_CG18740|SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-dependent;GO:0007476//imaginal disc-derived wing morphogenesis 19835049 663.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 39966 1766.77 33.02 24.205 -0.448035026052403 Down 0.566503764364021 CG7497 CG7497, isoform C K04261|1|1e-12|75.1|nve:NEMVE_v1g91884|prostaglandin E receptor 4;K04258|2|4e-09|63.2|hsa:5731|prostaglandin E receptor 1 GO:0031224//intrinsic to membrane GO:0004672//protein kinase activity;GO:0004888//transmembrane signaling receptor activity GO:0065008;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0030036//actin cytoskeleton organization 246627 4390.89 18.855 14.695 -0.359621791490331 Down 0.471899352793554 CG30463 CG30463, isoform E K00710|1|0.0|1227|dme:Dmel_CG30463|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0030246//carbohydrate binding;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0016740//transferase activity - 41532 1167.00 16.95 14.175 -0.257936538194115 Down 0.380597014925373 Aos1 Aos1 K10684|1|3e-179|627|dme:Dmel_CG12276|ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] - - - 37650 1062.00 0.33 0.77 1.22239242133645 Up 0.236890767401928 CG32833 CG32833 K01362|1|7e-27|121|dme:Dmel_CG17240| [EC:3.4.21.-];K01312|2|2e-24|113|dpo:Dpse_GA20562|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 2768971 1620.00 0.425 0.47 0.145197915539936 Up 0.0638290846651697 CG33489 CG33489, isoform B - - - - 34072 811.00 0.485 0.81 0.739937160697497 Up 0.182769779421477 CG14537 CG14537 - - - - 34102 983.00 4.295 7.23 0.751337515812654 Up 0.504160612864879 Trf TBP-related factor K03120|1|8e-110|396|dme:Dmel_CG7562|transcription initiation factor TFIID TATA-box-binding protein GO:0005667//transcription factor complex;GO:0005694//chromosome GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation 37891 855.00 2.17 3.08 0.505235308250422 Up 0.292002377493066 CG13578 CG13578 - - - - 36705 3040.00 3.36 4.1 0.287162676726686 Up 0.235569937921014 Pms2 Pms2 K10858|1|0.0|1719|dme:Dmel_CG8169|DNA mismatch repair protein PMS2 GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0003690//double-stranded DNA binding;GO:0032559 GO:0006281//DNA repair 41296 2452.00 1.445 1.02 -0.502500340529183 Down 0.198685774666491 Mcm5 minichromosome maintenance 5 K02209|1|0.0|1415|dsi:Dsim_GD18709|minichromosome maintenance protein 5 (cell division control protein 46) GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0032559;GO:0003678//DNA helicase activity GO:0007131//reciprocal meiotic recombination;GO:0006270//DNA replication initiation;GO:0010468//regulation of gene expression;GO:0051276//chromosome organization;GO:0006915//apoptotic process 46074 1104.97 14.455 20.115 0.476703129148581 Up 0.540054154008717 l(2)06496 lethal (2) 06496, isoform B K10425|1|3e-102|372|dme:Dmel_CG9893|dynactin 3 GO:0005875//microtubule associated complex - - 40135 1893.49 28.63 30.52 0.0922272918351776 Up 0.207964601769911 CG9368 CG9368, isoform D - - - - 41423 5662.60 21.995 23.24 0.0794344674944049 Up 0.180326244881786 l(3)neo38 lethal (3) neo38, isoform L K09228|1|4e-22|106|ecb:100061107|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 45757 3066.00 28.17 24.615 -0.194621824140062 Down 0.351472724871219 beta'Cop coat protein (coatomer) beta' K05236|1|2e-70|267|aag:AaeL_AAEL013098|coatomer protein complex, subunit alpha (xenin) GO:0030120//vesicle coat GO:0005488//binding GO:0006900//membrane budding;GO:0019915//lipid storage;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 38128 580.00 1.305 2.03 0.637429920615292 Up 0.272421080438515 LysE lysozyme E K01185|1|4e-75|280|dme:Dmel_CG1180|lysozyme [EC:3.2.1.17];K01183|3|2e-73|274|dme:Dmel_CG9118|chitinase [EC:3.2.1.14];K13915|5|4e-68|256|dwi:Dwil_GK12154|lysozyme C [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 45021 1200.61 8.82 6.395 -0.463834296675884 Down 0.433265090476819 Zfrp8 zinc finger protein RP-8, isoform B - GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0017145//stem cell division;GO:0030097//hemopoiesis 31062 823.28 0.605 1.01 0.7393482454772 Up 0.206610751551975 CG11379 CG11379, isoform B - - - - 34181 1294.65 73.42 88.19 0.264441961205596 Up 0.474871219125611 Dh31 diuretic hormone 31, isoform C - - GO:0005179//hormone activity;GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0046903//secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0046903//secretion 36740 3628.37 119.645 128.93 0.107827887911323 Up 0.276053361511029 Zasp52 Z band alternatively spliced PDZ-motif protein 52, isoform W K07520|1|3e-06|53.5|nvi:100123688|actin-binding LIM protein GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding GO:0007160//cell-matrix adhesion;GO:0007160//cell-matrix adhesion;GO:0007160//cell-matrix adhesion 19835852 888.00 0.92 1.125 0.290219235160024 Up 0.120261524237221 34891 3992.67 11.865 15.535 0.388810140927893 Up 0.469455818253863 dao down and out, isoform C - - - - 42936 1438.86 19.05 21.505 0.174881133563965 Up 0.310659093910976 ash2 absent, small, or homeotic discs 2, isoform E K11485|1|1e-08|61.6|api:100167748|polycomb-like protein 2;K12169|2|3e-07|57.4|dvi:Dvir_GJ23222|Kip1 ubiquitination-promoting complex protein 1 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0003002//regionalization;GO:0007472//wing disc morphogenesis;GO:0003002//regionalization;GO:0007472//wing disc morphogenesis 12798034 1512.00 3.56 3.39 -0.0705919678300538 Down 0.0821225729758288 12798267 339.00 2.055 1.59 -0.370111628397328 Down 0.198421608770308 35647 2403.00 0.21 0.315 0.584962500721156 Up 0.0978074230616827 CG1850 CG1850 - - - - 319052 2206.00 0.32 0.14 -1.1926450779424 Down 0.145654471007793 CG31975 CG31975, isoform C - - - - 39836 2146.00 10.07 9.025 -0.158064846232252 Down 0.231310262845067 st scarlet K05681|1|2e-65|250|cin:100177505|ATP-binding cassette, subfamily G (WHITE), member 2;K05679|2|1e-64|248|tgu:100222171|ATP-binding cassette, subfamily G (WHITE), member 1;K05680|4|8e-64|245|cfa:610604|ATP-binding cassette, subfamily G (WHITE), member 4 GO:0043234//protein complex;GO:0016021//integral to membrane GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0032559 GO:0006810//transport;GO:0006726//eye pigment biosynthetic process 40743 2373.00 0.29 0.595 1.03683676818037 Up 0.189671113459252 CG15580 CG15580 - - - - 35563 945.88 15.865 12.14 -0.386079099661956 Down 0.470875709945846 geminin geminin, isoform B K10749|1|4e-95|347|dme:Dmel_CG3183|geminin GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0007173//epidermal growth factor receptor signaling pathway 34374 861.00 17.9 16.79 -0.0923573572145887 Down 0.184949148064985 CG4957 CG4957 - - - - 2768977 902.00 4.76 3.49 -0.447734537098291 Down 0.33456610751552 CG33260 CG33260 K01170|1|3e-15|82.0|cin:100186340|tRNA-intron endonuclease [EC:3.1.27.9] GO:0043234//protein complex GO:0005488//binding;GO:0004549//tRNA-specific ribonuclease activity GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation 31614 2097.14 45.555 49.845 0.129839384524572 Up 0.29286091665566 CG14439 CG14439, isoform C - - - GO:0006810//transport;GO:0006810//transport 35853 1053.78 0.225 0.645 1.51937415909358 Up 0.240159820367191 Jon44E jonah 44E, isoform B K01310|1|2e-92|338|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|5e-89|327|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33049 3229.00 7.03 11.295 0.684087676320549 Up 0.543587372870162 CG1812 CG1812 K10459|1|2e-54|214|hsa:84861|kelch-like protein 22;K10463|5|3e-53|211|dre:558035|kelch-like protein 26 - GO:0005488//binding - 8673992 3974.18 10.29 12.325 0.260344664371305 Up 0.346981904636112 CG42388 CG42388, isoform H K10356|1|4e-10|67.8|nvi:100122007|myosin I;K13738|2|1e-09|66.2|ecb:100068514|CD2-associated protein - - - 34188 1718.00 6.96 8.34 0.260960077595935 Up 0.300719852067098 CG13091 CG13091, isoform B K13356|1|2e-94|346|cqu:CpipJ_CPIJ018289|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 19836080 1120.00 0.175 0.045 -1.95935801550265 Down 0.129276185444459 38940 1001.00 0.08 0.095 0.247927513443586 Up 0.0524039096552635 Cpr66Cb cuticular protein 66Cb - - GO:0005198//structural molecule activity - 36606 1839.00 20.79 16.145 -0.364802317244389 Down 0.481673490952318 phyl phyllopod - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0001709//cell fate determination;GO:0007264//small GTPase mediated signal transduction;GO:0042051//compound eye photoreceptor development;GO:0007219//Notch signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0001752//compound eye photoreceptor fate commitment;GO:0035466 14462703 763.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 39626 2225.00 14.115 13.89 -0.0231825294683003 Down 0.0708625016510369 CG10006 Zinc/iron regulated transporter-related protein 71B - GO:0044464//cell part GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport 19835698 811.00 0.29 0.345 0.250543461650597 Up 0.0674943864747061 3772094 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33900 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 32608 7899.00 0.96 1.085 0.176588731723323 Up 0.0874719323735306 mei-41 meiotic 41 K06640|1|0.0|4916|dme:Dmel_CG4252|ataxia telangiectasia and Rad3 related [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0000726;GO:0065008;GO:0007143//female meiosis;GO:0000724//double-strand break repair via homologous recombination;GO:0051276//chromosome organization;GO:0006796//phosphate-containing compound metabolic process;GO:0048513//organ development;GO:0030036//actin cytoskeleton organization;GO:0009792//embryo development ending in birth or egg hatching;GO:0007067//mitosis;GO:0009628//response to abiotic stimulus;GO:0051322//anaphase;GO:0007292//female gamete generation;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0031570 35116 2097.99 25.725 24.43 -0.0745172135140745 Down 0.169858671245542 MESR3 misexpression suppressor of ras 3, isoform D - - - - 39029 1712.00 24.645 21.06 -0.226789544645514 Down 0.383634922731475 CG5644 CG5644 - - - - 34123 1011.00 7.25 6.92 -0.0672089572655722 Down 0.109298639545635 CG8353 CG8353, isoform B K01489|1|2e-93|341|dme:Dmel_CG8353|cytidine deaminase [EC:3.5.4.5] - GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding GO:0046131 42685 2504.00 0.185 0.22 0.249978253008348 Up 0.0625742966583014 CG13842 CG13842 - - - - 318590 696.00 0.525 1.155 1.13750352374994 Up 0.28325188218201 CG31088 CG31088 K12033|1|4e-07|53.9|mmu:101700|tripartite motif-containing protein 68;K12171|3|1e-06|52.8|xla:431855|E3 ubiquitin-protein ligase SH3RF1 [EC:6.3.2.19] GO:0044424//intracellular part GO:0005488//binding;GO:0003824//catalytic activity - 34689 3505.00 0.455 1.03 1.17870588698452 Up 0.272718267071721 ACXC ACXC, isoform B K01768|1|0.0|1415|dme:Dmel_CG17174|adenylate cyclase [EC:4.6.1.1];K03458|3|0.0|1063|dya:Dyak_GE18608|nucleobase:cation symporter-2, NCS2 family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0009975//cyclase activity;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0048232//male gamete generation;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0048232//male gamete generation 37222 2768.00 0.07 0.035 -1 Down 0.0654471007792894 CG10051 CG10051 - - - - 2768914 588.47 31.365 35.755 0.188989440663711 Up 0.363426231673491 CG33307 CG33307, isoform B - - - - 32137 484.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 CG15741 CG15741 - - - - 39052 4199.01 131.57 155.595 0.241965130751404 Up 0.465262184651961 nwk nervous wreck, isoform L K12470|1|3e-13|77.4|gga:418608|SH3 domain-containing kinase-binding protein 1;K07365|2|2e-12|74.7|dan:Dana_GF15078|NCK adaptor protein - - - 34226 932.00 1.69 1.54 -0.134092895587283 Down 0.0893210936468102 Try29F trypsin 29F, isoform D K01312|1|9e-153|539|dme:Dmel_CG9564|trypsin [EC:3.4.21.4] GO:0005576//extracellular region GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39608 4445.47 16.51 18.42 0.157932941178078 Up 0.282624488178576 CG9384 CG9384, isoform B K00738|1|0.0|1161|dme:Dmel_CG9384|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145] GO:0044464//cell part GO:0016757//transferase activity, transferring glycosyl groups GO:0044238//primary metabolic process 41349 1409.00 9.15 9.4 0.038889013393595 Up 0.0868445383700964 CG17726 CG17726 - - - - 36221 810.00 2.51 15.83 2.65690198618641 Up 0.751584995377097 gammaTry gammaTrypsin K01312|1|3e-107|387|dme:Dmel_CG30031|trypsin [EC:3.4.21.4] GO:0005576//extracellular region GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38561 3005.08 20.355 21.275 0.0637759104333147 Up 0.146843217540615 CG11357 CG11357, isoform D K09664|1|7e-107|388|dpo:Dpse_GA10945|beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-];K07819|2|3e-29|130|isc:IscW_ISCW003730|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-];K07820|5|2e-27|125|dre:798349|beta-1,3-galactosyltransferase 2 [EC:2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 40034 1785.00 12.755 20.19 0.662578011729001 Up 0.598566900013208 GNBP1 Gram-negative bacteria binding protein 1 - GO:0005626//insoluble fraction GO:0004872//receptor activity;GO:0051635//bacterial cell surface binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0042742//defense response to bacterium;GO:0002376//immune system process 43486 1764.00 0.055 0.075 0.447458976971221 Up 0.0547483819838859 ppk20 pickpocket 20, isoform C - GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport;GO:0007166//cell surface receptor signaling pathway 34745 837.00 59.24 47.135 -0.329772912539051 Down 0.527077004358737 CG6523 CG6523 K07390|1|5e-21|101|dvi:Dvir_GJ17033|monothiol glutaredoxin - GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis 39474 2215.00 1.93 1.475 -0.387885893018877 Down 0.195218597279091 CG11261 CG11261 K03347|1|1e-47|191|dwi:Dwil_GK21971|cullin 1 GO:0000151//ubiquitin ligase complex GO:0019899//enzyme binding GO:0019941//modification-dependent protein catabolic process 19835555 762.00 0.21 0.18 -0.222392421336448 Down 0.0573900409457139 5740264 662.00 0.545 0.275 -0.986824611252267 Down 0.174481574428741 CG34175 CG34175 - - - - 19835309 997.00 0.08 0.01 -3 Down 0.110718531237617 40029 3231.00 0.15 0.2 0.415037499278844 Up 0.073702285035002 CG13380 CG13380, isoform D K00472|1|0.0|640|dme:Dmel_CG4174|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0019471 39339 1412.00 0.84 0.63 -0.415037499278844 Down 0.132380134724607 CG7264 CG7264, isoform B K05702|1|1e-06|55.1|spu:589923|afadin - - - 19835115 619.00 0.075 0.075 0 - 0.0382380134724607 34046 2069.00 1.225 0.88 -0.477206320365274 Down 0.177354378549729 Ntl neurotransmitter transporter-like, isoform B K05040|1|1e-105|384|bfo:BRAFLDRAFT_117178|solute carrier family 6 (neurotransmitter transporter, L-proline) member 7;K05038|5|9e-104|377|cin:100185022|solute carrier family 6 (neurotransmitter transporter, glycine) member 5 GO:0005739//mitochondrion;GO:0016021//integral to membrane;GO:0005739//mitochondrion;GO:0016021//integral to membrane GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006810//transport;GO:0003006//developmental process involved in reproduction;GO:0006810//transport;GO:0003006//developmental process involved in reproduction 37723 3845.00 6.185 7.655 0.307628782523418 Up 0.327565711266675 mi minus - - - - 32397 3338.11 65.27 86.575 0.407530443120558 Up 0.586778496896051 CG9413 CG9413, isoform D K13868|1|0.0|1018|dse:Dsec_GM17545|solute carrier family 7 (L-type amino acid transporter), member 9 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0006865//amino acid transport;GO:0006865//amino acid transport 43742 2114.00 0.57 0.675 0.243925582886089 Up 0.0878681812178048 salt salty dog, isoform C K03307|1|3e-95|349|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport 40588 2799.20 28.075 20.325 -0.466030670325574 Down 0.563300752872804 Nep2 neprilysin 2, isoform C K08635|1|2e-155|550|tca:660501|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 318566 4122.28 11.3 11.07 -0.0296675505209979 Down 0.0789195614846123 CG34133 CG34133, isoform E K12602|1|2e-13|79.0|tca:664186|WD repeat-containing protein 61;K13124|2|1e-11|72.8|nve:NEMVE_v1g245850|mitogen-activated protein kinase organizer 1;K12857|3|5e-11|70.9|hmg:100208671|Prp8 binding protein - - - 19835715 874.00 0.565 0.45 -0.328325866085513 Down 0.0994254391758024 33621 2070.10 4.755 5.335 0.166042929963861 Up 0.181680095099723 Sr-CI scavenger receptor class C, type I, isoform B K01316|1|8e-10|65.9|oaa:100079480|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K06724|2|2e-09|64.3|dre:353246|neuropilin 1;K06819|3|3e-09|63.9|oaa:100076251|neuropilin 2;K04003|4|4e-09|63.5|rno:24236|complement component 4 binding protein, beta GO:0016021//integral to membrane GO:0001871;GO:0004888//transmembrane signaling receptor activity GO:0042742//defense response to bacterium;GO:0002376//immune system process;GO:0006897//endocytosis 31503 1983.00 12.7 12.735 0.00397046261466635 Up 0.0434552899220711 CG3097 CG3097 K01298|1|3e-67|256|gga:416682|carboxypeptidase A2 [EC:3.4.17.15];K01300|3|1e-65|251|oaa:100083738|carboxypeptidase B2 [EC:3.4.17.20];K08637|4|5e-64|245|mmu:71791|carboxypeptidase A4 [EC:3.4.17.-] - - - 12798140 463.00 2.035 2.065 0.0211129871531983 Up 0.046559239202219 CG43326 CG43326, isoform B - - - - 35827 1786.00 0.51 0.475 -0.102569733640548 Down 0.0512812045964866 Mal-A4 maltase A4 K01187|1|0.0|1191|dme:Dmel_CG8693|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding;GO:0015926//glucosidase activity GO:0019318//hexose metabolic process 38931 1339.00 24.215 20.51 -0.239573511121773 Down 0.393012812045965 CG7197 CG7197 K07977|1|1e-99|363|dya:Dyak_GE21319|Arf/Sar family, other GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 39909 867.00 1.29 0.27 -2.25633975325979 Down 0.391559899616959 Ilp8 Insulin-like peptide 8 - - GO:0003676//nucleic acid binding GO:0010467//gene expression 44851 3616.84 31.165 28.74 -0.116866650953548 Down 0.257594769515256 raw raw, isoform E - - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0065008;GO:0007439//ectodermal digestive tract development;GO:0007399//nervous system development;GO:0033036;GO:0007392;GO:0007431//salivary gland development;GO:0048102//autophagic cell death;GO:0043408//regulation of MAPK cascade;GO:0065008;GO:0007439//ectodermal digestive tract development;GO:0007399//nervous system development;GO:0033036;GO:0007392;GO:0007431//salivary gland development;GO:0048102//autophagic cell death;GO:0043408//regulation of MAPK cascade;GO:0065008;GO:0007439//ectodermal digestive tract development;GO:0007399//nervous system development;GO:0033036;GO:0007392;GO:0007431//salivary gland development;GO:0048102//autophagic cell death;GO:0043408//regulation of MAPK cascade 40214 1240.00 0.04 0.01 -2 Down 0.0694426099590543 CG6933 CG6933, isoform E - - GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding GO:0006022;GO:0006022;GO:0006022 36414 939.16 3.335 1.84 -0.857980995127572 Down 0.402952053889843 CG17575 CG17575, isoform B - - - GO:0045297//post-mating behavior;GO:0048609//multicellular organismal reproductive process;GO:0045297//post-mating behavior;GO:0048609//multicellular organismal reproductive process 3772136 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 35072 3218.75 10.21 11.19 0.132227170098592 Up 0.209153348302734 CG5674 CG5674, isoform E - - - - 32816 1878.00 1.815 1.45 -0.323916647980816 Down 0.168702945449742 CG6106 CG6106, isoform B K01466|1|0.0|927|dme:Dmel_CG6106|allantoinase [EC:3.5.2.5] - GO:0046914//transition metal ion binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0000255//allantoin metabolic process 318601 860.00 0.41 0.71 0.792195114886598 Up 0.178345000660415 CG31128 CG31128 - - - - 37337 752.00 12.62 13.245 0.0697359333870731 Up 0.139116365077269 CG11110 CG11110 K09648|1|2e-97|355|dse:Dsec_GM22032|mitochondrial inner membrane protease subunit 2 [EC:3.4.99.-] - - - 7354371 1253.78 8.18 7.86 -0.0575715306831423 Down 0.104345528992207 CG42374 CG42374, isoform B K07579|1|5e-121|434|dme:Dmel_CG9666|putative methylase - GO:0005488//binding;GO:0008168//methyltransferase activity GO:0006730//one-carbon metabolic process 34857 1301.00 0.59 0.72 0.287281952080471 Up 0.0994584599128253 CSN1a COP9 complex homolog subunit 1 a K12175|1|3e-68|259|bfo:BRAFLDRAFT_116394|COP9 signalosome complex subunit 1 GO:0043234//protein complex - GO:0031647//regulation of protein stability 44921 2324.00 125.43 0.085 -10.527131987515 Down 0.990655131422533 Hsp70Ba Heat-shock-protein-70Ba K03283|1|0.0|1147|dme:Dmel_CG31449|heat shock 70kDa protein 1/8 GO:0015630//microtubule cytoskeleton GO:0032559 GO:0034605//cellular response to heat 2768879 1084.00 1.635 9.495 2.53787736465142 Up 0.709978866728305 CG32500 CG32500 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0051540;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0031163 43477 715.00 0.17 0.5 1.55639334852439 Up 0.211497820631356 CG2014 CG2014, isoform B K03940|1|9e-117|419|dme:Dmel_CG2014|NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0051536//iron-sulfur cluster binding;GO:0046914//transition metal ion binding;GO:0048037//cofactor binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0006979//response to oxidative stress;GO:0010257;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain 33133 1565.86 13.77 14.03 0.0269864494849351 Up 0.0823537181349888 CG14613 CG14613, isoform B - - - - 42541 1815.59 3.32 3.465 0.0616721107902891 Up 0.0767401928411042 lbl ladybird late, isoform C K09353|1|4e-141|501|dme:Dmel_CG6570|homeobox protein LBX GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0006351//transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0014706//striated muscle tissue development;GO:0010468//regulation of gene expression;GO:0001708//cell fate specification;GO:0048870//cell motility;GO:0000768//syncytium formation by plasma membrane fusion;GO:0050767//regulation of neurogenesis;GO:0007560//imaginal disc morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0048666//neuron development;GO:0014706//striated muscle tissue development;GO:0010468//regulation of gene expression;GO:0001708//cell fate specification;GO:0048870//cell motility;GO:0000768//syncytium formation by plasma membrane fusion;GO:0050767//regulation of neurogenesis;GO:0007560//imaginal disc morphogenesis 7354405 795.00 0.265 0.595 1.16689730874474 Up 0.20238409721305 CG42391 CG42391 - - GO:0005543//phospholipid binding GO:0009987//cellular process 34844 3323.76 16.605 13.765 -0.270613112907147 Down 0.389149385814291 elB elbow B, isoform D - GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity GO:0007166//cell surface receptor signaling pathway;GO:0007444//imaginal disc development;GO:0060541//respiratory system development;GO:0007166//cell surface receptor signaling pathway;GO:0007444//imaginal disc development;GO:0060541//respiratory system development 35247 1297.00 4.61 5.395 0.226856209058679 Up 0.227314753665302 CG10337 CG10337 - - - - 35660 3683.85 19.91 19.865 -0.00326442763240365 Down 0.0434552899220711 Eaf ELL-associated factor, isoform D - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010468//regulation of gene expression;GO:0032501//multicellular organismal process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010468//regulation of gene expression;GO:0010557//positive regulation of macromolecule biosynthetic process 37869 822.00 30.46 26.895 -0.179577952897761 Down 0.34232598071589 DnaJ-60 DnaJ-like-60, isoform C K09524|1|2e-09|64.3|hsa:3338|DnaJ homolog subfamily C member 4;K09504|4|3e-08|60.1|gga:416671|DnaJ homolog subfamily A member 3 - GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation;GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation 31042 1681.73 32.84 25.21 -0.381458008919265 Down 0.530213974375908 TRAM TRAM, isoform E K14010|1|1e-176|619|dme:Dmel_CG11642|translocating chain-associated membrane protein 1 - - - 39294 725.34 38.065 34.595 -0.137901537347644 Down 0.298705587108704 CG7394 CG7394, isoform D K09539|1|5e-61|233|dme:Dmel_CG7394|DnaJ homolog subfamily C member 19 - GO:0005515//protein binding;GO:0005515//protein binding - 40105 7272.00 11.285 13.335 0.24081140635909 Up 0.337670056795668 CG32206 CG32206, isoform E K13046|1|1e-06|57.0|dmo:Dmoj_GI24022|tolkin [EC:3.4.24.-] - - - 31132 849.00 0.285 0.105 -1.44057259138598 Down 0.149385814291375 CG14811 CG14811 - - - - 42740 810.00 0.1 0.225 1.16992500144231 Up 0.118379342226919 CG13829 CG13829 - - - - 31513 4113.22 92.61 111.345 0.26579688588881 Up 0.489433364152688 CG15765 CG15765, isoform B - - - - 37933 899.00 0.825 1.31 0.667100787291635 Up 0.222526746796989 CG3565 CG3565 - - GO:0046872//metal ion binding - 41399 3970.73 7.065 6.92 -0.0299175226972146 Down 0.0680227182670717 Elp1 elongator complex protein 1, isoform C K11373|1|0.0|2376|dme:Dmel_CG10535|elongator complex protein 1 - - - 36533 2710.00 138.23 138.39 0.00166894101861326 Up 0.0462620525690133 synaptogyrin synaptogyrin K04403|1|8e-29|129|tgu:100223478|TAK1-binding protein 1 GO:0031224//intrinsic to membrane - GO:0006887//exocytosis 42034 3903.71 0.375 0.2 -0.906890595608518 Down 0.139050323603223 Ubx ultrabithorax, isoform F K09311|1|1e-108|395|dme:Dmel_CG10388|Antp family, other;K09307|3|1e-16|90.1|tgu:100231939|homeobox protein HoxA/B7;K09306|4|2e-16|89.4|rno:497986|homeobox protein HoxA/B/C6 - - - 5740243 535.00 0.385 0.175 -1.13750352374993 Down 0.157244749702813 CG34203 CG34203 - - - - 40922 2381.39 0.82 0.67 -0.291462814160311 Down 0.104939902258618 CG3014 CG3014, isoform C - - - - 5740769 1406.00 0.01 0.155 3.95419631038688 Up 0.171410645885616 CG44005 CG44005, isoform B - - - - 38881 1340.00 14.53 13.86 -0.0681074454956278 Down 0.142649583938714 CG8111 CG8111 - - - - 37544 2181.00 0.26 0.175 -0.571156701196126 Down 0.0892550521727645 Oatp58Db organic anion transporting polypeptide 58Db - GO:0044464//cell part - GO:0006820//anion transport 32541 2048.57 76.83 79.53 0.0498294172697904 Up 0.152522784308546 UBL3 UBL3, isoform C K01530|1|2e-20|101|bfo:BRAFLDRAFT_69708|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 3771910 1023.00 0.07 0.025 -1.48542682717024 Down 0.0803064324395721 His1:CG33828 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 34839 2321.00 3.91 5.045 0.367685661799005 Up 0.305177651565183 l(2)34Fd lethal (2) 34Fd - GO:0043231//intracellular membrane-bounded organelle - - 41986 2597.95 11.93 8.87 -0.427588033394164 Down 0.458327829877163 CG14880 CG14880, isoform B - - - - 35054 2421.73 17.035 20.38 0.258652104069467 Up 0.39723946638489 fws four way stop, isoform I - - - GO:0033206//cytokinesis after meiosis;GO:0000212//meiotic spindle organization;GO:0032506;GO:0033206//cytokinesis after meiosis;GO:0000212//meiotic spindle organization;GO:0032506 34317 1027.03 11.48 11.715 0.0292343121874477 Up 0.0789195614846123 CG4592 CG4592, isoform B K13238|1|2e-84|312|dwi:Dwil_GK18281|3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8] GO:0043231//intracellular membrane-bounded organelle - - 33088 1259.59 0.265 0.43 0.698344300138899 Up 0.124290054154009 CG15446 CG15446, isoform D - GO:0044464//cell part GO:0046914//transition metal ion binding - 3346220 788.00 0.055 0.23 2.06413033741972 Up 0.157376832650905 CG33552 CG33552 - - GO:0046914//transition metal ion binding - 43422 676.50 0.43 0.895 1.05755102256216 Up 0.238277638356888 eIF4E-6 eIF4E-6, isoform C K03259|1|8e-104|375|dme:Dmel_CG1442|translation initiation factor eIF-4E GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death 14462586 448.00 0.465 0.315 -0.561878887608115 Down 0.116332056531502 36046 1012.00 23.495 17.325 -0.43949841537654 Down 0.53671905956941 sel seele K01647|1|5e-14|78.6|mcc:709604|citrate synthase [EC:2.3.3.1] - - - 40184 1917.00 1.335 2.31 0.791053109728504 Up 0.327400607581561 schuy schumacher-levy - - - - 49808 1195.00 57.41 40.8 -0.492732903412412 Down 0.609265618808612 Spn42Dd serpin 42Dd K13963|1|0.0|705|dme:Dmel_CG9456|serpin B - GO:0004866//endopeptidase inhibitor activity - 35816 1186.00 43.455 41.99 -0.0494763971565426 Down 0.144267600052833 CSN7 COP9 complex homolog subunit 7 K12180|1|9e-146|516|dme:Dmel_CG2038|COP9 signalosome complex subunit 7 - GO:0008135//translation factor activity, nucleic acid binding GO:0010467//gene expression 14462390 991.00 0.06 0.31 2.36923380966572 Up 0.193336415268789 19835281 605.00 0.01 0.225 4.49185309632967 Up 0.222989037115308 42068 909.00 0.175 0.385 1.13750352374993 Up 0.157244749702813 CG31265 CG31265 K11997|1|3e-44|178|ame:409206|tripartite motif-containing protein 2/3;K01312|2|4e-35|148|mcc:698352|trypsin [EC:3.4.21.4] - - - 33469 664.00 32.135 33.805 0.073091174775413 Up 0.176594901598204 Taf10 TBP-associated factor 10 K03134|1|3e-85|314|dme:Dmel_CG2859|transcription initiation factor TFIID subunit D8 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 40143 4352.15 23.43 26.795 0.193606861848158 Up 0.348401796328094 wnd wallenda, isoform D K04422|1|0.0|643|ame:410119|mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 317828 743.00 0.275 0.36 0.388565287917652 Up 0.0868115176330736 CG32024 CG32024 - - GO:0030247//polysaccharide binding GO:0006022 19836172 470.00 12.215 14.48 0.245407738815949 Up 0.353850217936864 3772032 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33839 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 5740694 540.00 35.79 41.465 0.212337548579993 Up 0.39492801479329 19835623 5443.00 0.065 0.035 -0.893084796083488 Down 0.0629375247655528 38331 1513.63 5.05 4.35 -0.215267986903067 Down 0.212356359793951 Aats-pro Prolyl-tRNA synthetase, isoform B K01881|1|0.0|907|dme:Dmel_CG12186|prolyl-tRNA synthetase [EC:6.1.1.15] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0007033//vacuole organization 32806 841.00 0.235 0.42 0.837728571101123 Up 0.136375643904372 CG15059 CG15059, isoform C - - - - 39015 3876.49 1.2 1.145 -0.0676868075115745 Down 0.0561022322018227 TrpA1 transient receptor potential cation channel A1 ortholog, isoform K K04984|1|0.0|2394|dme:Dmel_CG5751|transient receptor potential cation channel subfamily A member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006810//transport;GO:0006810//transport 31463 3287.71 15.985 18.535 0.213533371038635 Up 0.342656188086118 SPR Sex peptide receptor, isoform C K08430|1|7e-13|76.6|dre:100000501|G protein-coupled receptor 142;K08428|2|3e-11|71.2|gga:431418|G protein-coupled receptor 139 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0016491//oxidoreductase activity GO:0046662//regulation of oviposition;GO:0008152//metabolic process;GO:0007621//negative regulation of female receptivity;GO:0007166//cell surface receptor signaling pathway 12798284 5339.00 2.27 1.555 -0.545777717160312 Down 0.262316734909523 246489 927.00 1.69 1.675 -0.0128621509370494 Down 0.041044776119403 CG30157 CG30157, isoform B K01376|1|1e-22|107|dre:336782| [EC:3.4.22.-] - GO:0016788//hydrolase activity, acting on ester bonds - 34843 2462.00 2.01 2.31 0.200697350237129 Up 0.135186897371549 ppk pickpocket K04832|1|7e-43|176|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|2|1e-11|72.0|dre:407670|amiloride-sensitive cation channel 2, neuronal;K04830|4|5e-11|70.1|ecb:100063408|amiloride-sensitive cation channel 3 GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0007626//locomotory behavior;GO:0030001//metal ion transport 318210 3307.00 0.58 1.105 0.92992156426386 Up 0.247523444723286 CG32786 CG32786 - - - - 14462403 321.00 1.3 0.315 -2.04508788952854 Down 0.382512217672698 38121 2183.00 14.22 17.895 0.331635078796969 Up 0.447596090344737 Trh tryptophan hydroxylase K00502|1|0.0|1070|dse:Dsec_GM14234|tryptophan 5-monooxygenase [EC:1.14.16.4] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0001071//nucleic acid binding transcription factor activity;GO:0031406//carboxylic acid binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0048812//neuron projection morphogenesis;GO:0042428//serotonin metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0042749//regulation of circadian sleep/wake cycle;GO:0006520//cellular amino acid metabolic process;GO:0001709//cell fate determination;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0048598//embryonic morphogenesis 246576 941.00 5.845 6.47 0.146562687460851 Up 0.181581032888654 CG30376 CG30376 - - - - 39506 1101.00 0.365 0.355 -0.0400774393753352 Down 0.0418702945449742 CG14106 CG14106 - - - - 19836208 1129.00 0.04 0.01 -2 Down 0.0694426099590543 40260 1873.03 29.23 23.445 -0.318169550085232 Down 0.48157442874125 Psn presenilin, isoform E K06060|1|0.0|847|dse:Dsec_GM22291|presenilin, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part - GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0033619//membrane protein proteolysis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006996//organelle organization;GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0033619//membrane protein proteolysis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006996//organelle organization;GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0033619//membrane protein proteolysis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006996//organelle organization 41764 483.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 CG8087 CG8087 - - - - 14462399 313.00 0.01 0.165 4.04439411935845 Up 0.184883106590939 41619 795.00 1.04 0.72 -0.53051471669878 Down 0.17157574957073 CG8138 CG8138 - - - - 12798521 423.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 36820 1696.00 8.82 8.1 -0.122856747785534 Down 0.179533747193237 CG7747 CG7747 K10598|1|0.0|975|dme:Dmel_CG7747|peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity GO:0000377;GO:0044267//cellular protein metabolic process 31565 3028.70 9.02 10.005 0.14952182865036 Up 0.22011623299432 Top3beta topoisomerase 3beta, isoform B K03165|1|0.0|1696|dme:Dmel_CG3458|DNA topoisomerase III [EC:5.99.1.2] - - - 32133 3028.14 127.915 111.755 -0.19484607223143 Down 0.40453704926694 Hsc70-3 heat shock 70-kDa protein cognate 3, isoform E K09490|1|0.0|1174|dme:Dmel_CG4147|heat shock 70kDa protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0035194//posttranscriptional gene silencing by RNA;GO:0006950//response to stress;GO:0007610//behavior;GO:0035194//posttranscriptional gene silencing by RNA;GO:0006950//response to stress;GO:0007610//behavior;GO:0035194//posttranscriptional gene silencing by RNA;GO:0006950//response to stress;GO:0007610//behavior;GO:0035194//posttranscriptional gene silencing by RNA;GO:0006950//response to stress;GO:0007610//behavior 33313 2103.71 77.585 41.285 -0.91016004877408 Down 0.706940958922203 CG5397 CG5397, isoform B K01044|1|9e-44|178|mmu:13897|carboxylesterase [EC:3.1.1.1];K03927|3|1e-42|174|mmu:72361|carboxylesterase type B [EC:3.1.1.1] - - - 34899 814.00 0.82 1.395 0.766569307211104 Up 0.249834896314886 CG15260 CG15260 - - - - 35710 717.00 0.06 0.135 1.16992500144231 Up 0.0983357548540483 CG12826 CG12826 - - - - 33845 2105.02 21.465 20.02 -0.10054419861183 Down 0.208691057984414 mtm myotubularin, isoform B K01112|1|0.0|1148|dpo:Dpse_GA21553| [EC:3.1.3.-] - GO:0004721//phosphoprotein phosphatase activity GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 36544 7672.50 48.545 50.8 0.0655057872783213 Up 0.183463214898957 AGO1 Argonaute-1, isoform D K11593|1|0.0|1857|dan:Dana_GF11153|eukaryotic translation initiation factor 2C GO:0043231//intracellular membrane-bounded organelle;GO:0031332;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031332;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031332;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0008135//translation factor activity, nucleic acid binding GO:0016246//RNA interference;GO:0006401//RNA catabolic process;GO:0006379//mRNA cleavage;GO:0007365//periodic partitioning;GO:0035195//gene silencing by miRNA;GO:0007399//nervous system development;GO:0016246//RNA interference;GO:0006401//RNA catabolic process;GO:0006379//mRNA cleavage;GO:0007365//periodic partitioning;GO:0035195//gene silencing by miRNA;GO:0007399//nervous system development;GO:0016246//RNA interference;GO:0006401//RNA catabolic process;GO:0006379//mRNA cleavage;GO:0007365//periodic partitioning;GO:0035195//gene silencing by miRNA;GO:0007399//nervous system development 40866 1863.00 0.065 0.67 3.36564947231668 Up 0.330603619072778 CG14606 CG14606, isoform B K08145|1|5e-33|142|spu:582285|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane - GO:0006909//phagocytosis 42789 2012.00 50.655 53.065 0.0670559384957714 Up 0.185081231013076 eIF-3p66 eukaryotic initiation factor 3 p66 subunit K03251|1|0.0|1072|dme:Dmel_CG10161|translation initiation factor eIF-3 subunit 7 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding GO:0006413//translational initiation 33071 2531.00 0.26 0.285 0.13245029602365 Up 0.0538238013472461 CG11227 CG11227, isoform C - - - - 318211 2054.00 22.89 22.865 -0.00157654374872323 Down 0.0427618544445912 HIP Hsc/Hsp70-interacting protein K09560|1|3e-63|243|dre:564225|suppressor of tumorigenicity protein 13 - - - 19836157 1087.00 0.185 0.16 -0.20945336562895 Down 0.0516774534407608 40841 1796.00 20.565 20.225 -0.024051369183042 Down 0.0782921674811782 CG1105 CG1105 K01277|1|3e-09|63.5|tca:661730|dipeptidyl-peptidase III [EC:3.4.14.4] - - - 318128 595.00 0.49 0.44 -0.155278225477911 Down 0.0640932505613525 CG32625 CG32625 K02728|1|2e-06|51.6|ame:413757|20S proteasome subunit alpha 3 [EC:3.4.25.1] - - - 31201 3767.43 45.59 45.515 -0.0023753285222454 Down 0.0449742438251222 Vinc vinculin, isoform C K05700|1|0.0|1643|dme:Dmel_CG3299|vinculin - - - 38722 2805.00 0.445 0.76 0.772194082477188 Up 0.183760401532162 CG8219 CG8219 - GO:0005635//nuclear envelope;GO:0016020//membrane GO:0008565//protein transporter activity;GO:0005488//binding GO:0007411//axon guidance;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0015031//protein transport;GO:0035146 19836253 946.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 - CG44341 - - - - 38494 1620.00 36.17 34.235 -0.0793215855636384 Down 0.194789327697794 Ras64B Ras oncogene at 64B K07830|1|1e-100|367|dme:Dmel_CG1167|Ras-related protein R-Ras2 GO:0044464//cell part GO:0001883//purine nucleoside binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction 44522 6206.00 4.455 4.265 -0.0628796902036317 Down 0.0850614185708625 lea leak, isoform B K06754|1|7e-138|493|mdo:100027033|roundabout, axon guidance receptor 2;K06753|4|1e-134|482|ptr:460518|roundabout, axon guidance receptor 1 - - - 5740194 752.00 0.455 0.34 -0.420331798948357 Down 0.102628450667019 42658 1722.00 5.195 3.03 -0.777805955431261 Down 0.458360850614186 CG5278 CG5278 K10250|1|8e-62|237|hsa:79993|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane - - 12798324 565.00 0.43 0.485 0.17364808748503 Up 0.0680227182670717 CG43371 CG43371 - - - - 35820 527.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 Lcp4 larval cuticle protein 4, isoform B - - GO:0042302//structural constituent of cuticle - 12798430 1733.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 261618 606.00 14.465 22.94 0.665299068086225 Up 0.610652489763572 CG31740 CG31740 - - - - 43342 649.00 0.19 0.555 1.54648835290652 Up 0.225069343547748 CG12426 CG12426 - - - - 32325 919.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 CG11162 CG11162 K07750|1|7e-68|256|tca:654920|methylsterol monooxygenase [EC:1.14.13.72] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0006631//fatty acid metabolic process 36330 2755.14 14.48 12.905 -0.166131460989235 Down 0.273741909919429 CG42700 CG42700, isoform J - - - - 41294 1350.65 36.585 43.345 0.244613324182665 Up 0.429599788667283 Rbp1 RNA-binding protein 1, isoform D K12896|1|7e-26|118|tca:657225|splicing factor, arginine/serine-rich 7;K12892|2|3e-25|116|cin:100180129|splicing factor, arginine/serine-rich 3 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000245//spliceosomal complex assembly;GO:0000245//spliceosomal complex assembly 34934 2055.56 0.865 1.42 0.715118891867957 Up 0.241480649848105 Tektin-A tektin A, isoform B K04688|1|9e-14|79.0|aag:AaeL_AAEL000743|p70 ribosomal S6 kinase [EC:2.7.11.1];K10352|3|3e-07|57.4|bmy:Bm1_00655|myosin heavy chain GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding GO:0007010//cytoskeleton organization 32601 5678.00 4.32 3.95 -0.129178659099003 Down 0.136606789063532 sl small wing K05859|1|0.0|2361|dme:Dmel_CG4200|phospholipase C, gamma [EC:3.1.4.11] - GO:0060089;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity GO:0007297//ovarian follicle cell migration;GO:0006644//phospholipid metabolic process;GO:0023033;GO:0023060 117294 3337.54 34.355 36.32 0.0802441195896099 Up 0.195218597279091 Dsp1 dorsal switch protein 1, isoform G K10802|1|6e-133|475|dme:Dmel_CG12223|high mobility group protein B1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding GO:0016568//chromatin modification;GO:0002759//regulation of antimicrobial humoral response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051099//positive regulation of binding;GO:0007444//imaginal disc development;GO:0007389//pattern specification process;GO:0016568//chromatin modification;GO:0002759//regulation of antimicrobial humoral response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051099//positive regulation of binding;GO:0007444//imaginal disc development;GO:0007389//pattern specification process;GO:0016568//chromatin modification;GO:0002759//regulation of antimicrobial humoral response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051099//positive regulation of binding;GO:0007444//imaginal disc development;GO:0007389//pattern specification process;GO:0016568//chromatin modification;GO:0002759//regulation of antimicrobial humoral response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051099//positive regulation of binding;GO:0007444//imaginal disc development;GO:0007389//pattern specification process;GO:0016568//chromatin modification;GO:0002759//regulation of antimicrobial humoral response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051099//positive regulation of binding;GO:0007444//imaginal disc development;GO:0007389//pattern specification process;GO:0016568//chromatin modification;GO:0002759//regulation of antimicrobial humoral response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051099//positive regulation of binding;GO:0007444//imaginal disc development;GO:0007389//pattern specification process 32630 7929.51 12.08 13.425 0.152301633547696 Up 0.248315942411835 Nup153 nucleoporin 153kD, isoform D K03348|1|6e-75|284|dgr:Dgri_GH24489|anaphase-promoting complex subunit 1;K12172|5|6e-43|177|hsa:5903|E3 SUMO-protein ligase RanBP2 - - GO:0006606//protein import into nucleus;GO:0006997//nucleus organization;GO:0006606//protein import into nucleus;GO:0006997//nucleus organization;GO:0006606//protein import into nucleus;GO:0006997//nucleus organization 32243 1323.00 19.14 17.11 -0.161751069996612 Down 0.286917183991547 CG4400 BRMS1 ortholog - - - - 31315 1518.00 0.305 0.365 0.259087221317131 Up 0.0724144762911108 CG16781 CG16781, isoform B K10660|1|0.0|741|dme:Dmel_CG16781|E3 ubiquitin-protein ligase MARCH5 [EC:6.3.2.19] - - - 19835950 934.00 0.1 0.13 0.37851162325373 Up 0.0612534671773874 44018 2845.00 0.035 0.02 -0.807354922057604 Down 0.0552767137762515 cas castor, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0005049//nuclear export signal receptor activity GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0007420//brain development;GO:0014016//neuroblast differentiation;GO:0001709//cell fate determination;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0050793//regulation of developmental process 43002 3627.76 9.25 11.355 0.295802435303213 Up 0.371483291507066 CG34349 Unc-13 ortholog 4B, isoform E K02677|1|7e-10|67.0|spu:578578|classical protein kinase C [EC:2.7.11.13] - - - 19834943 4902.00 0.175 0.255 0.543142325026529 Up 0.0890899484876502 38060 1243.00 6.14 6.045 -0.0224963161210558 Down 0.0573900409457139 CG1231 CG1231 K10137|1|3e-10|66.6|dre:561535|zinc finger, matrin type 3;K13203|4|8e-07|55.1|aag:AaeL_AAEL008171|zinc finger RNA-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0046914//transition metal ion binding - 31789 3227.00 0.075 0.18 1.26303440583379 Up 0.108836349227315 otu ovarian tumor, isoform E K13718|1|0.0|1533|dme:Dmel_CG12743|OTU domain-containing protein 4 GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007542;GO:0006996//organelle organization;GO:0032875//regulation of DNA endoreduplication;GO:0008283//cell proliferation;GO:0007542;GO:0006996//organelle organization;GO:0032875//regulation of DNA endoreduplication;GO:0008283//cell proliferation;GO:0007542;GO:0006996//organelle organization;GO:0032875//regulation of DNA endoreduplication;GO:0008283//cell proliferation 19836121 673.00 1.6 2.04 0.350497247084133 Up 0.189109760929864 34648 3447.41 27.1 23.95 -0.178267195617691 Down 0.335259542993 aret arrest, isoform K K02177|1|0.0|819|dme:Dmel_CG31762|bruno GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0017148//negative regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0002118//aggressive behavior;GO:0007096//regulation of exit from mitosis;GO:0007281//germ cell development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007293//germarium-derived egg chamber formation;GO:0017148//negative regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0002118//aggressive behavior;GO:0007096//regulation of exit from mitosis;GO:0007281//germ cell development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007293//germarium-derived egg chamber formation;GO:0017148//negative regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0002118//aggressive behavior;GO:0007096//regulation of exit from mitosis;GO:0007281//germ cell development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007293//germarium-derived egg chamber formation;GO:0017148//negative regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0002118//aggressive behavior;GO:0007096//regulation of exit from mitosis;GO:0007281//germ cell development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007293//germarium-derived egg chamber formation;GO:0017148//negative regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0002118//aggressive behavior;GO:0007096//regulation of exit from mitosis;GO:0007281//germ cell development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007293//germarium-derived egg chamber formation 31919 2108.00 3.46 3.475 0.00624093997414496 Up 0.041044776119403 CG15247 CG15247 - - - - 32964 897.00 0.54 0.755 0.48351723716161 Up 0.135087835160481 CG14212 CG14212 K01112|1|3e-36|152|dpo:Dpse_GA11499| [EC:3.1.3.-];K13248|2|3e-27|122|mmu:73373|pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74] - GO:0042578//phosphoric ester hydrolase activity - 39947 7737.25 2.32 2.615 0.17268614111937 Up 0.131158367454762 CG18265 CG18265, isoform C - - - - 38073 5507.00 8.285 8.155 -0.0228168205095677 Down 0.0624091929731872 MED14 mediator complex subunit 14, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0016251//general RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 42539 2616.00 0.05 0.115 1.20163386116965 Up 0.0859859992075023 CG7907 CG7907, isoform C K12882|1|0.0|1269|dsi:Dsim_GD19424|nuclear cap-binding protein subunit 1 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000377;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000377;GO:0035194//posttranscriptional gene silencing by RNA 40617 1853.00 12.755 13.715 0.104691723245805 Up 0.18524633469819 CG12007 CG12007 K05956|1|3e-40|166|hmg:100204907|geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60];K05955|4|1e-11|72.0|cel:R02D3.5|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59] GO:0043234//protein complex GO:0004659//prenyltransferase activity GO:0009987//cellular process;GO:0065008 33141 1287.86 12.235 18.71 0.612795457161394 Up 0.580405494650641 CG17600 CG17600, isoform D - GO:0031224//intrinsic to membrane GO:0016301//kinase activity - 33490 998.00 3.195 3.98 0.316952499596655 Up 0.250561352529388 CG8813 CG8813 - - - - 32639 1729.00 5.79 4.11 -0.494424954307554 Down 0.38264430062079 CG9723 CG9723 - - - - 42353 1800.00 0.69 2.95 2.09604668747103 Up 0.532294280808348 CG11391 CG11391 K01904|1|4e-41|169|spu:581911|4-coumarate--CoA ligase [EC:6.2.1.12];K01896|5|6e-20|99.4|rno:353317|medium-chain acyl-CoA synthetase [EC:6.2.1.2] - - - 33867 1290.00 0.86 1.615 0.909125599991827 Up 0.299266939638093 CG9222 CG9222 K08811|1|0.0|682|dme:Dmel_CG9222|testis-specific serine kinase [EC:2.7.11.1] - GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0048869//cellular developmental process 34676 881.00 1.72 1.265 -0.443271180007788 Down 0.202053889842821 CG5780 CG5780 - - - - 19835317 729.00 11.76 8.33 -0.497499659470817 Down 0.488310659093911 36150 1549.00 12.4 19.82 0.676616841912251 Up 0.601241579712059 nclb no child left behind K10143|1|1e-12|74.7|tca:663449|E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19] GO:0005667//transcription factor complex - - 37491 1115.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 CG9294 CG9294 K09637|1|3e-45|182|mmu:71753|transmembrane protease, serine 6 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 5740421 208.00 57.785 81.735 0.500258949326821 Up 0.624091929731872 41411 836.00 1.27 0.995 -0.352060066228517 Down 0.149517897239466 Fer3 48 related 3 K09073|1|9e-09|60.5|bfo:BRAFLDRAFT_121333|pancreas-specific transcription factor 1a - GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression 33337 2227.00 2.55 4.025 0.658491536143122 Up 0.381224408928807 CG10869 CG10869 - - - - 31624 890.00 0.36 0.33 -0.125530882083859 Down 0.0538238013472461 Atx-1 ataxin 1 - - - - 40309 1763.15 9.68 8.835 -0.131776912722978 Down 0.197662131818782 CG11456 CG11456, isoform C K09228|1|2e-16|73.6|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 42711 1164.00 0.14 0.165 0.237039197300849 Up 0.0524039096552635 Or94a odorant receptor 94a K08471|1|0.0|751|dme:Dmel_CG17241|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0007166//cell surface receptor signaling pathway;GO:0023060 53556 3466.89 28.49 32.845 0.205218143886423 Up 0.380861180821556 dbo diablo, isoform B K10457|1|0.0|1200|dan:Dana_GF24095|kelch-like protein 20 - GO:0008092//cytoskeletal protein binding GO:0050794//regulation of cellular process;GO:0040007//growth 37265 571.00 0.745 1.23 0.723345984877078 Up 0.225432571654999 Obp56b Odorant-binding protein 56b - - - - 43394 2597.00 0.03 0.025 -0.263034405833794 Down 0.0467903843613789 CG10000 CG10000 K00710|1|0.0|1152|dme:Dmel_CG10000|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0030246//carbohydrate binding;GO:0016740//transferase activity - 36390 3543.05 12.9 15.285 0.244745486576354 Up 0.35368511425175 Iswi imitation SWI, isoform C K11654|1|0.0|1781|dme:Dmel_CG8625|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.1.-] GO:0070603//SWI/SNF superfamily-type complex;GO:0005678//chromatin assembly complex;GO:0005694//chromosome;GO:0031010;GO:0070603//SWI/SNF superfamily-type complex;GO:0005678//chromatin assembly complex;GO:0005694//chromosome;GO:0031010;GO:0070603//SWI/SNF superfamily-type complex;GO:0005678//chromatin assembly complex;GO:0005694//chromosome;GO:0031010 GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003682//chromatin binding GO:0032583;GO:0048812//neuron projection morphogenesis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0034728//nucleosome organization;GO:0048513//organ development;GO:0006338//chromatin remodeling;GO:0032583;GO:0048812//neuron projection morphogenesis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0034728//nucleosome organization;GO:0048513//organ development;GO:0006338//chromatin remodeling;GO:0032583;GO:0048812//neuron projection morphogenesis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0034728//nucleosome organization;GO:0048513//organ development;GO:0006338//chromatin remodeling 40394 1892.00 1 2.23 1.15704371014558 Up 0.389083344340246 CG7634 CG7634 - - - - 44392 981.00 4.665 4.2 -0.151487753185636 Down 0.159721304979527 Rpp30 RNaseP protein p30, isoform B K03539|1|8e-162|569|dme:Dmel_CG11606|ribonuclease P subunit Rpp30 [EC:3.1.26.5] GO:0030529//ribonucleoprotein complex GO:0004518//nuclease activity GO:0006399//tRNA metabolic process 19835579 580.00 0.285 0.435 0.610053481683987 Up 0.117454761590279 40054 1440.00 2.27 2.335 0.0407302524187468 Up 0.0559371285167085 Rad9 Rad9, isoform B K10994|1|7e-34|145|cin:100175771|cell cycle checkpoint control protein RAD9A [EC:3.1.11.2];K10995|2|6e-32|139|mdo:100020133|cell cycle checkpoint control protein RAD9B GO:0044464//cell part;GO:0044464//cell part - GO:0030001//metal ion transport;GO:0006259//DNA metabolic process;GO:0030001//metal ion transport;GO:0006259//DNA metabolic process 35079 2046.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 CG31741 CG31741 K13885|1|4e-53|209|bta:282346|scavenger receptor class B, member 1 GO:0044464//cell part - GO:0009987//cellular process 43383 4252.35 5.31 6.84 0.365284464081744 Up 0.347939506009774 fkh fork head, isoform D K08035|1|0.0|677|dya:Dyak_GE10507|forkhead box protein A2, hepatocyte nuclear factor 3-beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035071//salivary gland cell autophagic cell death;GO:0048565//digestive tract development;GO:0043066//negative regulation of apoptotic process;GO:0001704//formation of primary germ layer;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035071//salivary gland cell autophagic cell death;GO:0048565//digestive tract development;GO:0043066//negative regulation of apoptotic process;GO:0001704//formation of primary germ layer 32190 896.00 1.04 1.02 -0.028014376169597 Down 0.0445449742438251 CG2574 CG2574 K06689|1|2e-121|434|dme:Dmel_CG2574|ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process 19834971 322.00 1.025 2.09 1.02787903257544 Up 0.357185312376172 35529 5110.00 21.21 15.22 -0.47877626202701 Down 0.545601637828556 SCAP SREBP cleavage activating protein K10260|1|1e-17|93.2|api:100166211|F-box and WD-40 domain protein 7 GO:0031224//intrinsic to membrane - - 318146 368.00 234.55 160.625 -0.546199046527378 Down 0.659325056135253 CG32667 short spindle 7 - - - - 38410 1103.00 2.61 2.08 -0.327466278428792 Down 0.206412627129838 CG12077 phosphatidylinositol glycan anchor biosynthesis, class C ortholog K03859|1|5e-158|556|dme:Dmel_CG12077|phosphatidylinositol glycan, class C GO:0031224//intrinsic to membrane GO:0008375//acetylglucosaminyltransferase activity GO:0006497//protein lipidation 38544 2744.00 1.61 1.03 -0.644416350931398 Down 0.241579712059173 CG15020 CG15020 - - - - 41174 1392.00 0.77 1.655 1.10390086611232 Up 0.329811121384229 nmdyn-D7 nmdyn-D7 K00940|1|0.0|744|dme:Dmel_CG8362|nucleoside-diphosphate kinase [EC:2.7.4.6] - GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559 GO:0009209;GO:0009206 36170 2378.00 12.905 14.33 0.151108468168176 Up 0.252443534539691 CG12391 CG12391 K09228|1|1e-11|72.4|mdo:100014233|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 246515 628.00 0.325 0.425 0.387023123109247 Up 0.0939770175670321 CG43325 CG43325, isoform C - - - - 31471 1084.00 0.215 0.28 0.381090167355506 Up 0.0819904900277374 CG34435 CG34435 K12752|1|2e-11|69.3|tca:662551|myosin light chain, invertebrate GO:0015629//actin cytoskeleton GO:0046872//metal ion binding - 37767 2507.00 7.905 8.29 0.0686066391373795 Up 0.116067890635319 Ssrp structure specific recognition protein K09272|1|0.0|943|dme:Dmel_CG4817|structure-specific recognition protein 1 GO:0008023//transcription elongation factor complex GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0006333//chromatin assembly or disassembly;GO:0051098//regulation of binding 33564 1511.00 53.885 40.115 -0.425741927716973 Down 0.580900805705983 CG3246 CG3246 - - - - 32691 2050.67 1.725 2.005 0.217005874789389 Up 0.132776383568881 CG4949 CG4949, isoform C - - GO:0005488//binding;GO:0005488//binding - 35623 1029.00 19.115 21.1 0.142537798759899 Up 0.26842557125875 lbm late bloomer, isoform B K06497|1|2e-13|76.6|dan:Dana_GF13154|CD63 antigen GO:0031224//intrinsic to membrane - GO:0007399//nervous system development 37199 2706.26 44.37 55.49 0.322643249830907 Up 0.517170783251882 CG15118 CG15118, isoform E - - - - 36673 4222.55 23.88 22.5 -0.0858778351604056 Down 0.195251618016114 ckn caskin, isoform F K05102|1|1e-06|56.2|mdo:100011941|Eph receptor A1 [EC:2.7.10.1];K05106|2|4e-06|54.7|gga:395997|Eph receptor A5 [EC:2.7.10.1] - - - 40502 1376.00 0.805 1.815 1.17290885988113 Up 0.354774798573504 CG32459 CG32459 - - - - 43193 680.00 79.585 119.125 0.581907768515645 Up 0.658268392550522 Pdf Pigment-dispersing factor - - GO:0005179//hormone activity GO:0009648//photoperiodism;GO:0007562//eclosion;GO:0022410;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007626//locomotory behavior;GO:0009629//response to gravity 36944 766.00 18.185 31.51 0.793060828561923 Up 0.657013604543653 CG12699 CG12699 - - - - 39734 1029.67 23.59 23.02 -0.0352875851072322 Down 0.111279883767006 GXIVsPLA2 GXIVsPLA2, isoform D K01047|1|1e-123|442|dpo:Dpse_GA14287|phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity;GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process;GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 40270 1896.92 10.04 9.925 -0.0166202619204517 Down 0.0598335754854048 isoQC iso glutaminyl cyclase, isoform B K00683|1|8e-174|610|dme:Dmel_CG5976|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016755;GO:0016787//hydrolase activity;GO:0016755;GO:0016787//hydrolase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 47186 6750.00 2.27 2.645 0.220575424823111 Up 0.155692775062739 mus205 mutagen-sensitive 205 K02350|1|0.0|3875|dme:Dmel_CG1925|DNA polymerase zeta subunit [EC:2.7.7.7] GO:0042575 GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding;GO:0034061 GO:0006301//postreplication repair 50290 894.00 57.55 48.365 -0.250852529462671 Down 0.450964205521067 CG14132 CG14132 - - - - 34093 2646.25 17.645 14.495 -0.283704096718327 Down 0.405791837273808 Tg transglutaminase, isoform B K00680|1|0.0|1468|dme:Dmel_CG7356| [EC:2.3.1.-];K00686|1|0.0|1468|dme:Dmel_CG7356|protein-glutamine gamma-glutamyltransferase [EC:2.3.2.13];K05619|2|1e-123|444|rno:60335|transglutaminase 1 [EC:2.3.2.13] - GO:0016755;GO:0016755 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 43829 1697.43 1929.535 1888.785 -0.0307947238863335 Down 0.117520803064324 ATPsyn-beta ATP synthase-beta, isoform D K02133|1|0.0|891|der:Dere_GG16404|F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] - - - 14462741 565.00 0.225 0.355 0.657894023175007 Up 0.11121384229296 36086 2707.00 3.305 3.71 0.166768915113112 Up 0.153447364945186 JhI-1 juvenile hormone-inducible protein 1 K00784|1|0.0|1472|dme:Dmel_CG3298|ribonuclease Z [EC:3.1.26.11] GO:0043231//intracellular membrane-bounded organelle GO:0004521//endoribonuclease activity GO:0042780//tRNA 3'-end processing;GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation 5740847 2036.00 0.04 0.205 2.35755200461808 Up 0.151135913353586 CG17636 CG17636, isoform C K00681|1|1e-170|599|dan:Dana_GF22409|gamma-glutamyltranspeptidase [EC:2.3.2.2] - GO:0016755 - 19835310 651.00 0.07 0.14 1 Up 0.0917316074494783 42791 1267.00 136.56 111.265 -0.295535119832158 Down 0.524270241711795 SPE Spatzle-Processing enzyme K01362|1|4e-89|328|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|3|6e-58|224|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0008592//regulation of Toll signaling pathway;GO:0051605;GO:0002812 42100 3081.00 11.615 2.445 -2.24808278385657 Down 0.713446044115705 CG5873 CG5873 K00431|1|5e-85|316|oaa:100080616|thyroid peroxidase [EC:1.11.1.8] - - - 246647 917.00 1.025 0.995 -0.0428554789617971 Down 0.0480451723682473 CG30488 antares, isoform B - - - - 34488 1535.00 6.99 8.285 0.245209241846015 Up 0.288964469686963 CG6724 CG6724, isoform B K01062|1|5e-22|105|bta:282513|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0043234//protein complex;GO:0031981//nuclear lumen - GO:0000470//maturation of LSU-rRNA 33083 3518.03 24.975 31.875 0.351940663953802 Up 0.509311847840444 bves bves, isoform D - GO:0044464//cell part;GO:0044464//cell part - - 117462 530.00 10.125 13.91 0.45820051188289 Up 0.492306168273676 TotC turandot C - GO:0044421//extracellular region part - GO:0051707//response to other organism;GO:0009416//response to light stimulus;GO:0006952//defense response;GO:0009605//response to external stimulus 12798279 169.00 15.69 13.525 -0.21421675825392 Down 0.327598732003698 Acp98AB accessory gland protein 98AB - - - - 34768 488.00 0.845 1.04 0.299560281858908 Up 0.119369964337604 CG15638 CG15638 - - - - 19835587 487.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 38295 1431.00 0.16 0.21 0.39231742277876 Up 0.0730748910315678 yellow-g2 yellow-g2 - - - - 8674051 337.00 2.575 0.585 -2.13806390248718 Down 0.510566635847312 Sfp33A2 seminal fluid protein 33A2 - - - - 36335 1452.75 6.98 7.75 0.150969273951948 Up 0.200204728569542 CG13163 CG13163, isoform B K02520|1|3e-108|391|dme:Dmel_CG13163|translation initiation factor IF-3 - GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 40883 1380.00 0.695 0.72 0.0509839287188049 Up 0.0483423590014529 CG10029 CG10029, isoform B K08056|1|1e-21|104|cbr:CBG10789|protein disulfide isomerase family A, member 3 [EC:5.3.4.1];K09582|3|1e-20|100|hmg:100204811|protein disulfide-isomerase A4 [EC:5.3.4.1] - - GO:0019725//cellular homeostasis 40221 1113.61 129.36 123.91 -0.0620989608666921 Down 0.177486461497821 Clc clathrin light chain, isoform D K04645|1|5e-20|98.6|cin:100178066|clathrin, light polypeptide B;K04644|2|1e-19|97.4|ecb:100055375|clathrin, light polypeptide A GO:0030118//clathrin coat;GO:0005905//coated pit;GO:0030665//clathrin-coated vesicle membrane;GO:0030118//clathrin coat;GO:0005905//coated pit;GO:0030665//clathrin-coated vesicle membrane;GO:0030118//clathrin coat;GO:0005905//coated pit;GO:0030665//clathrin-coated vesicle membrane GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels 318663 1425.00 3.875 3.865 -0.00372789623675249 Down 0.0401862369568089 CG31287 CG31287, isoform B - - GO:0005515//protein binding GO:0044267//cellular protein metabolic process 34411 1082.00 0.655 1.075 0.71476984805201 Up 0.208228767666094 cdc2 cdc2 K02087|1|3e-172|604|dya:Dyak_GE26009|cyclin-dependent kinase 1 [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0048136;GO:0007127//meiosis I;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment;GO:0007282//cystoblast division;GO:0006464//cellular protein modification process;GO:0007140//male meiosis;GO:0033554//cellular response to stress 43680 801.00 3.97 2.015 -0.97835916861499 Down 0.45690793818518 CG15554 CG15554 - - - - 5740472 4859.00 5.315 6.525 0.295908209926142 Up 0.299729229956413 Fili Fish-lips, isoform D K08129|1|4e-25|118|dre:568821|nyctalopin;K04308|2|5e-25|117|rno:299802|leucine-rich repeat-containing G protein-coupled receptor 5 - GO:0005488//binding - 14462850 390.00 0.22 0.37 0.750021746991653 Up 0.122176726984546 CG43993 CG43993 - - - - 19834840 324.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 251690 911.00 12.66 10.49 -0.271262726851074 Down 0.359034473649452 CG32147 CG32147 K01304|1|2e-127|454|dme:Dmel_CG32147|pyroglutamyl-peptidase [EC:3.4.19.3] - GO:0008242//omega peptidase activity GO:0019538//protein metabolic process 35624 1003.62 9.755 9 -0.116216871391989 Down 0.183000924580637 Tsp42En tetraspanin 42En, isoform B - GO:0031224//intrinsic to membrane - - 34350 7237.00 0.64 0.915 0.515699838284042 Up 0.15906089023907 Sur sulfonylurea receptor K05032|1|1e-50|203|rno:25559|ATP-binding cassette subfamily C (CFTR/MRP) member 8 GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0016829//lyase activity;GO:0032559 GO:0006810//transport;GO:0009987//cellular process 33269 1185.00 10.585 9.61 -0.139412933233839 Down 0.214865935807687 dbe dribble K06961|1|8e-171|599|dme:Dmel_CG4258| GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis 3771875 543.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 CG33920 CG33920 K09255|1|8e-22|102|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|4e-10|63.9|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 48445 1944.00 10.635 10.37 -0.0364041391474467 Down 0.0896182802800159 Acph-1 acid phosphatase 1, isoform B K01078|1|0.0|877|dme:Dmel_CG7899|acid phosphatase [EC:3.1.3.2] - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity - 261614 775.27 0.57 0.63 0.144389909335175 Up 0.0661405362567692 CG31867 CG31867, isoform B - - - - 31168 3478.08 30.215 23.34 -0.372460380992323 Down 0.518788799366002 moody moody, isoform F K08421|1|1e-30|135|oaa:100084002|G protein-coupled receptor 84 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0009987//cellular process;GO:0023060;GO:0007399//nervous system development;GO:0065007//biological regulation;GO:0007166//cell surface receptor signaling pathway;GO:0009987//cellular process;GO:0023060;GO:0007399//nervous system development;GO:0065007//biological regulation;GO:0007166//cell surface receptor signaling pathway;GO:0009987//cellular process;GO:0023060;GO:0007399//nervous system development;GO:0065007//biological regulation;GO:0007166//cell surface receptor signaling pathway 32248 1359.00 0.5 1.02 1.02856915219677 Up 0.253236032228239 CG12716 CG12716 - - - - 38795 1260.00 10.125 8.385 -0.272039219095003 Down 0.332981112138423 Neos neosin, isoform B K13189|1|7e-06|52.0|dre:402858|RNA-binding protein 14 GO:0005681//spliceosomal complex GO:0016876//ligase activity, forming aminoacyl-tRNA and related compounds;GO:0032559 GO:0000377 39022 1394.00 0.595 0.92 0.628744192749069 Up 0.178477083608506 CG13313 CG13313 - - - - 36455 3137.68 3.225 3.335 0.0483876008739685 Up 0.0674943864747061 FLASH FLASH ortholog, isoform B K04574|1|2e-08|62.4|cfa:442940|neurofilament heavy polypeptide - - - 43660 2640.00 24.1 34.165 0.503485980357314 Up 0.589255052172765 CG12071 CG12071, isoform E K09228|1|1e-11|72.0|mmu:245368|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0046914//transition metal ion binding;GO:0032559;GO:0046914//transition metal ion binding GO:0009209;GO:0006909//phagocytosis;GO:0009206;GO:0006909//phagocytosis;GO:0009201;GO:0046483//heterocycle metabolic process 37357 1691.00 0.18 0.055 -1.71049338280501 Down 0.12349755646546 CG17999 CG17999 K01904|1|1e-46|187|spu:581911|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 35351 1085.30 34.625 51.82 0.581694944356181 Up 0.635285959582618 CG31676 CG31676, isoform B - - - - 31958 2018.00 5.08 4.335 -0.228796503550331 Down 0.222064456478669 CG2909 CG2909 - - - - 37119 2235.47 138.645 188.54 0.443475044268134 Up 0.616100911372342 CG30118 CG30118, isoform C - - - - 32296 1593.50 20.56 16.425 -0.323946893984186 Down 0.454332320697398 CG1662 CG1662, isoform B K13348|1|2e-34|146|tgu:100229975|protein Mpv17;K13347|2|2e-15|84.0|dre:447868|peroxisomal membrane protein 2;K13349|4|4e-15|82.4|mmu:93734|Mpv17-like protein GO:0031224//intrinsic to membrane - - 317926 1293.00 89.99 92.695 0.0427268283985134 Up 0.133667943468498 CG32225 CG32225 K06528|1|4e-10|65.9|phu:Phum_PHUM465120|lysosomal-associated membrane protein 1/2 GO:0044464//cell part - - 37020 1687.52 3.325 3.655 0.136517065563885 Up 0.131752740721173 CG6401 CG6401, isoform B K03857|1|0.0|882|dme:Dmel_CG6401|phosphatidylinositol glycan, class A [EC:2.4.1.198] - - - 37125 1726.00 0.305 0.52 0.769702380578206 Up 0.149484876502444 CG17669 CG17669 - - - - 39742 1395.31 32.845 28.585 -0.200415475276521 Down 0.371186104873861 CG17027 CG17027, isoform B K01092|1|2e-128|459|dya:Dyak_GE22871|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] - GO:0004437//inositol or phosphatidylinositol phosphatase activity GO:0006796//phosphate-containing compound metabolic process 42958 3642.41 34.505 48.53 0.492071427123208 Up 0.602562409192973 Saf-B scaffold attachment factor B, isoform D K13195|1|2e-06|55.5|bfo:BRAFLDRAFT_71461|cold-inducible RNA-binding protein - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 43282 2472.00 1.75 2.45 0.485426827170242 Up 0.255580504556862 CG5987 CG5987 K06047|1|2e-14|81.3|xtr:100135000|tubulin---tyrosine ligase [EC:6.3.2.25];K05755|4|1e-13|78.6|ecb:100058358|actin related protein 2/3 complex, subunit 4 - GO:0016881//acid-amino acid ligase activity GO:0043412//macromolecule modification 317952 1143.60 65.56 36.835 -0.831738611812752 Down 0.691817461365738 CG32280 CG32280, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 35701 1515.00 111.09 72.84 -0.608926127915948 Down 0.663716814159292 Rpt1 regulatory particle triple-A ATPase 1 K03061|1|0.0|799|dme:Dmel_CG1341|26S proteasome regulatory subunit T1 GO:0043231//intracellular membrane-bounded organelle;GO:0005838//proteasome regulatory particle GO:0017111//nucleoside-triphosphatase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0032559 GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051704;GO:0033554//cellular response to stress 38752 4731.30 20.865 15.37 -0.440967755572624 Down 0.526482631092326 vvl ventral veins lacking, isoform D K09365|1|0.0|858|dme:Dmel_CG10037|POU domain transcription factor, class 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007411//axon guidance;GO:0001709//cell fate determination;GO:0007420//brain development;GO:0006351//transcription, DNA-dependent;GO:0007411//axon guidance;GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0006351//transcription, DNA-dependent 41236 1486.00 0.05 0.06 0.263034405833794 Up 0.0467903843613789 CG5361 CG5361 K01077|1|0.0|869|dme:Dmel_CG5361|alkaline phosphatase [EC:3.1.3.1] - GO:0042578//phosphoric ester hydrolase activity - 326133 3004.00 1.055 3.62 1.77874669837602 Up 0.542563730022454 CG31343 CG31343 K11140|1|0.0|900|dvi:Dvir_GJ23067|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 36468 879.00 321.165 229.69 -0.48362663148508 Down 0.637267203803989 Mp20 muscle protein 20, isoform C K06084|1|2e-07|56.6|tgu:100225324|F-box protein 20 GO:0043232;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion;GO:0065008;GO:0000768//syncytium formation by plasma membrane fusion 42439 2149.00 15.72 12.805 -0.295893964661138 Down 0.409159952450139 Srp72 signal recognition particle protein 72 K03108|1|0.0|1082|dme:Dmel_CG5434|signal recognition particle subunit SRP72 GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding GO:0050658//RNA transport;GO:0006613//cotranslational protein targeting to membrane 3772264 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33874 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 44437 1343.00 42.525 40.53 -0.0693210605039069 Down 0.181514991414608 sec13 Sec13 ortholog, isoform B K14004|1|0.0|644|dme:Dmel_CG6773|protein transport protein SEC13 - - GO:0008363//larval chitin-based cuticle development 39441 3615.69 3.605 4.59 0.348494894172985 Up 0.281798969753005 mirr mirror, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006351//transcription, DNA-dependent;GO:0007166//cell surface receptor signaling pathway;GO:0048859//formation of anatomical boundary;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0003006//developmental process involved in reproduction;GO:0010468//regulation of gene expression;GO:0009792//embryo development ending in birth or egg hatching;GO:0048592//eye morphogenesis;GO:0007399//nervous system development;GO:0007472//wing disc morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0007166//cell surface receptor signaling pathway;GO:0048859//formation of anatomical boundary;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0003006//developmental process involved in reproduction;GO:0010468//regulation of gene expression;GO:0009792//embryo development ending in birth or egg hatching;GO:0048592//eye morphogenesis;GO:0007399//nervous system development;GO:0007472//wing disc morphogenesis 35385 2335.00 16.865 17.475 0.0512601372446722 Up 0.122539955091798 Nbr nibbler K12591|1|3e-06|54.3|phu:Phum_PHUM247920|exosome complex exonuclease RRP6 [EC:3.1.13.-] GO:0044464//cell part GO:0005488//binding;GO:0004527//exonuclease activity GO:0034641//cellular nitrogen compound metabolic process 37288 1624.87 26.09 30.53 0.226730645389328 Up 0.397833839651301 Ate1 Ate1, isoform D K00685|1|0.0|875|dme:Dmel_CG9204|arginine-tRNA-protein transferase [EC:2.3.2.8] - - - 39214 597.00 167.725 170.195 0.0210909103658239 Up 0.0917646281865011 CG6463 CG6463 K03949|1|3e-66|250|dya:Dyak_GE20262|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 5 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0022904//respiratory electron transport chain 41014 4542.80 1.43 1.55 0.116253068495848 Up 0.0806696605468234 Cenp-C Cenp-C, isoform B - - - - 7354427 526.00 0.315 2.88 3.1926450779424 Up 0.588066305639942 CG42287 CG42287 - - - - 318559 2087.00 0.39 0.405 0.0544477840223765 Up 0.0451063267732136 spdo sanpodo - GO:0031224//intrinsic to membrane;GO:0005856//cytoskeleton;GO:0005768//endosome;GO:0031982//vesicle GO:0016491//oxidoreductase activity;GO:0005102//receptor binding GO:0008593//regulation of Notch signaling pathway;GO:0009887//organ morphogenesis;GO:0007399//nervous system development;GO:0008356//asymmetric cell division 12798007 255.00 1.175 2.055 0.806477637116683 Up 0.312277110025096 36352 557.03 1.09 2.635 1.27347482686029 Up 0.433793422269185 Cpr49Af cuticular protein 49Af, isoform B - - GO:0005198//structural molecule activity - 35256 1710.91 7.285 6.81 -0.0972741740524413 Down 0.141493858142914 Hakai hakai, isoform F - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 43271 4493.96 24.36 22.565 -0.110427354693845 Down 0.23134328358209 CG6051 CG6051, isoform D K04679|1|7e-13|77.0|ecb:100065363|MAD, mothers against decapentaplegic interacting protein - GO:0046872//metal ion binding - 2768858 3398.23 15.245 17.63 0.209696324310433 Up 0.336448289525822 dpr defective proboscis extension response, isoform B K05116|1|3e-07|58.2|rno:25232|TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1];K06772|3|3e-06|54.7|dre:664692|limbic system-associated membrane protein;K06550|4|4e-06|54.3|mmu:16728|L1 cell adhesion molecule - - GO:0007631//feeding behavior;GO:0050909//sensory perception of taste 42743 4682.50 52.85 40.495 -0.384159685104951 Down 0.554715361246863 cnc cap-n-collar, isoform P K09041|1|0.0|678|dme:Dmel_CG17894|nuclear factor erythroid 2, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006350;GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006350;GO:0006351//transcription, DNA-dependent;GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006351//transcription, DNA-dependent;GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006351//transcription, DNA-dependent;GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006351//transcription, DNA-dependent;GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006351//transcription, DNA-dependent;GO:0007017//microtubule-based process;GO:0045450//bicoid mRNA localization;GO:0010468//regulation of gene expression;GO:0044087;GO:0019094//pole plasm mRNA localization 59149 1241.00 0.225 0.11 -1.03242147769238 Down 0.117388720116233 CG18765 CG18765 - - - - 10178792 1691.06 1.23 0.655 -0.909091503801789 Down 0.258354246466781 CG42694 CG42694, isoform B K01334|1|4e-11|69.7|rno:54249|component factor D [EC:3.4.21.46];K08664|2|4e-11|69.7|rno:192107|protease, serine, 8 (prostasin) [EC:3.4.21.-];K09632|4|7e-11|68.9|gga:427531|chymotrypsin-like protease [EC:3.4.21.-];K09643|5|7e-11|68.9|rno:300682|transmembrane protease, serine 13 [EC:3.4.21.-] - GO:0016787//hydrolase activity - 36361 3816.82 17.755 18.92 0.0916867283184234 Up 0.186897371549333 CG8830 deubiquitinating apoptotic inhibitor, isoform B K11854|1|0.0|1523|dme:Dmel_CG8830|ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 37686 528.00 0.235 0.35 0.574694165267329 Up 0.101241579712059 CG13540 CG13540 - - - - 42991 1099.00 7 5.495 -0.349235440883098 Down 0.341599524501387 beta4GalT7 beta-4-galactosyltransferase 7 K00733|1|0.0|637|dme:Dmel_CG11780|xylosylprotein 4-beta-galactosyltransferase [EC:2.4.1.133] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016462//pyrophosphatase activity;GO:0035250//UDP-galactosyltransferase activity;GO:0032559 GO:0006024//glycosaminoglycan biosynthetic process;GO:0030166//proteoglycan biosynthetic process 3771726 1288.38 0.185 0.64 1.79054663437105 Up 0.258750495311055 39024 1463.00 30.275 4 -2.92005505480697 Down 0.790021133271695 CG5653 CG5653 K12259|1|1e-46|187|gga:422934|spermine oxidase [EC:1.5.3.16] - - - 36945 7423.52 45.025 67.005 0.573542479230774 Up 0.641758024039097 mbl mbl, isoform T - - - - 39189 1215.00 0.04 0.27 2.75488750216347 Up 0.187689869237881 Or67c odorant receptor 67c K08471|1|0.0|820|dme:Dmel_CG14156|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33544 2292.00 0.64 1.29 1.01122725542325 Up 0.282987716285827 CG3326 CG3326, isoform B K13254|1|3e-72|273|dre:405851|spastin [EC:3.6.4.3] - GO:0016462//pyrophosphatase activity;GO:0032559 - 249170 1463.00 1.04 0.895 -0.216623940876835 Down 0.0953969092590147 CG32236 CG32236 - - GO:0016859//cis-trans isomerase activity - 43602 1624.66 0.405 0.6 0.567040592723894 Up 0.131422533350944 CG9682 CG9682, isoform C - - - - 3354896 2300.12 40.36 39.935 -0.0152724607600715 Down 0.0811319508651433 vtd verthandi, isoform B K06670|1|0.0|1424|dme:Dmel_CG17436|cohesin complex subunit SCC1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000775//chromosome, centromeric region;GO:0005700//polytene chromosome;GO:0000793//condensed chromosome - GO:0000070//mitotic sister chromatid segregation;GO:0042551//neuron maturation;GO:0010467//gene expression 14462857 516.00 0.4 1.065 1.41278152533848 Up 0.299299960375116 33278 793.00 2.915 3.095 0.0864435260137682 Up 0.088033284902919 CG4375 CG4375 - - - - 48450 1895.21 110.735 133.13 0.265724423380365 Up 0.493230748910316 Dip-B dipeptidase B, isoform D K01255|1|0.0|1008|dme:Dmel_CG9285|leucyl aminopeptidase [EC:3.4.11.1] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 33734 1605.00 11 10.285 -0.0969617298870879 Down 0.167613261127988 CG14040 CG14040 - GO:0012505//endomembrane system;GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity;GO:0015144//carbohydrate transmembrane transporter activity GO:0008643//carbohydrate transport 3771957 595.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 His2B:CG33896 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 50191 350.00 27.975 37.62 0.427361717659439 Up 0.564588561616695 CG15353 CG15353 - - - - 19835104 603.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 35206 1175.00 0.365 0.55 0.591535154644643 Up 0.13218201030247 CG10750 CG10750, isoform B - - - - 41244 2006.00 8.685 9.65 0.15200309344505 Up 0.219191652357681 CG6254 CG6254 K09228|1|1e-40|167|cfa:484242|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 3772393 3798.00 1.41 1.97 0.482500467057582 Up 0.227215691454233 CG11566 CG11566 K04870|1|7e-11|70.5|dre:797409|voltage-dependent calcium channel gamma-5;K04872|4|2e-09|65.5|dre:100034540|voltage-dependent calcium channel gamma-7 GO:0031224//intrinsic to membrane - - 33217 2259.00 0.29 0.25 -0.214124805352848 Down 0.0611874257033417 BBS8 Bardet-Biedl syndrome 8 ortholog - - - GO:0051179//localization;GO:0010927 39394 1187.35 8.405 7.98 -0.0748590730138218 Down 0.121516312244089 thoc6 thoc6, isoform B K13175|1|0.0|671|dme:Dmel_CG5632|THO complex subunit 6 - - GO:0006405//RNA export from nucleus 8674030 793.34 86.13 83.71 -0.041115853787495 Down 0.132908466516973 CG17931 CG17931, isoform D - - - - 326150 1619.18 36.65 45.48 0.311419055871074 Up 0.499669792629772 CG31650 CG31650, isoform G K02183|1|1e-07|58.5|mdo:100022649|calmodulin - GO:0060089;GO:0046872//metal ion binding;GO:0060089;GO:0046872//metal ion binding;GO:0060089;GO:0046872//metal ion binding;GO:0060089;GO:0046872//metal ion binding;GO:0060089;GO:0046872//metal ion binding;GO:0060089;GO:0046872//metal ion binding - 35846 6894.43 70.295 60.395 -0.218992959550099 Down 0.426660943072249 Cirl Calcium-independent receptor for alpha-latrotoxin, isoform K K04593|1|5e-67|257|tgu:100223245|latrophilin 2;K04592|3|2e-64|249|oaa:100088198|latrophilin 1 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0007186//G-protein coupled receptor signaling pathway 32936 768.00 145.835 163.99 0.169270838878533 Up 0.378912957337208 CG12203 CG12203 K03937|1|5e-83|306|dme:Dmel_CG12203|NADH dehydrogenase (ubiquinone) Fe-S protein 4 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0016491//oxidoreductase activity GO:0006091//generation of precursor metabolites and energy 40279 1124.00 14.1 13.285 -0.0858969347956493 Down 0.168075551446308 mTerf3 mTerf3 - - - GO:0006261//DNA-dependent DNA replication;GO:0006351//transcription, DNA-dependent 35426 1593.44 41.38 36.525 -0.180049372169149 Down 0.357713644168538 CG1416 CG1416, isoform C - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding GO:0050896//response to stimulus;GO:0050896//response to stimulus;GO:0050896//response to stimulus 37887 2317.61 9.875 9.13 -0.113165887967606 Down 0.177156254127592 CG3394 CG3394, isoform B K08745|1|0.0|719|aag:AaeL_AAEL008144|solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] - - - 32771 4842.45 14.2 11.86 -0.259786919846041 Down 0.362468630299828 mnb minibrain, isoform I K08825|1|0.0|864|dya:Dyak_GE15563|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase [EC:2.7.12.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0007417//central nervous system development;GO:0008306//associative learning;GO:0006464//cellular protein modification process;GO:0048511//rhythmic process;GO:0007417//central nervous system development;GO:0008306//associative learning;GO:0006464//cellular protein modification process;GO:0048511//rhythmic process;GO:0007417//central nervous system development;GO:0008306//associative learning;GO:0006464//cellular protein modification process;GO:0048511//rhythmic process;GO:0007417//central nervous system development;GO:0008306//associative learning;GO:0006464//cellular protein modification process;GO:0048511//rhythmic process 38745 1303.00 3.635 2.78 -0.386870481196087 Down 0.271298375379738 CG8519 CG8519, isoform B K07974|1|4e-115|413|dme:Dmel_CG8519|Ras family, other;K07855|2|6e-31|133|spu:580352|Ras-like, estrogen-regulated, growth inhibitor GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 32774 1357.00 0.23 0.16 -0.523561956057013 Down 0.0840047549861313 CG12985 CG12985 - - - - 19835124 1305.00 0.305 0.365 0.259087221317131 Up 0.0724144762911108 33231 853.00 90.585 107.735 0.250142937302516 Up 0.468927486461498 CG2789 CG2789 K05770|1|1e-102|372|dsi:Dsim_GD23032|benzodiazapine receptor GO:0031224//intrinsic to membrane;GO:0031967 - - 39160 3269.00 31.11 28.395 -0.13174148310952 Down 0.276845859199577 iPLA2-VIA calcium-independent phospholipase A2 VIA, isoform D K01047|1|0.0|1652|dsi:Dsim_GD12885|phospholipase A2 [EC:3.1.1.4] - GO:0004623//phospholipase A2 activity;GO:0004623//phospholipase A2 activity;GO:0004623//phospholipase A2 activity;GO:0004623//phospholipase A2 activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 19834762 774.00 0.925 0.12 -2.94641895979516 Down 0.367091533483027 35968 1493.00 0.495 0.25 -0.985500430304885 Down 0.162561088363492 CG13955 CG13955 K05746|1|6e-06|51.6|xla:444086|enabled - - - 36208 1706.13 8.635 9.41 0.123998545199612 Up 0.18547747985735 CG7741 CG7741, isoform C - - - - 40907 1769.83 14.885 13.24 -0.168956099430819 Down 0.277737419099194 alpha-Est3 alpha-Esterase-3, isoform D K01044|1|0.0|1116|dme:Dmel_CG1257|carboxylesterase [EC:3.1.1.1];K03927|4|6e-136|484|dan:Dana_GF17295|carboxylesterase type B [EC:3.1.1.1];K01050|5|2e-130|466|dpo:Dpse_GA10907|cholinesterase [EC:3.1.1.8] - GO:0016788//hydrolase activity, acting on ester bonds;GO:0016788//hydrolase activity, acting on ester bonds - 32720 677.00 2.64 0.79 -1.74061337118135 Down 0.485702020869106 CG8661 CG8661 - - - - 19836212 1078.00 30.825 21.29 -0.533924944837908 Down 0.594076079778101 19835869 492.00 0.095 0.62 2.70626879694329 Up 0.296955488046493 31658 1060.00 18.83 26.29 0.481481142003818 Up 0.562871483291507 CG8300 CG8300 - - - - 34941 2832.00 0.03 0.14 2.22239242133645 Up 0.120954959714701 CG4793 CG4793 K09614|1|3e-22|107|dme:Dmel_CG2105|corin [EC:3.4.21.-];K01324|3|6e-22|106|mmu:16621|plasma kallikrein [EC:3.4.21.34];K09632|4|8e-21|102|gga:427531|chymotrypsin-like protease [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462542 1602.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 43084 681.00 6.81 4.685 -0.539605750352884 Down 0.426528860124158 CG5107 CG5107 - - - - 5740840 5675.95 7.935 8.36 0.0752727192457007 Up 0.125875049531106 Shawl Shaw-like, isoform D K05320|1|0.0|973|dse:Dsec_GM12484|potassium voltage-gated channel Shaw-related subfamily C, invertebrate GO:0005887//integral to plasma membrane GO:0046914//transition metal ion binding;GO:0005267//potassium channel activity GO:0030001//metal ion transport;GO:0007610//behavior 37472 644.00 0.375 0.775 1.04730571477836 Up 0.221767269845463 CG15676 CG15676, isoform B - GO:0043234//protein complex GO:0005515//protein binding GO:0044267//cellular protein metabolic process 53427 3557.00 0.065 0.145 1.15754127698648 Up 0.0982366926429798 ACXB ACXB K01768|1|0.0|2121|dme:Dmel_CG17174|adenylate cyclase [EC:4.6.1.1];K03458|3|0.0|978|dya:Dyak_GE18608|nucleobase:cation symporter-2, NCS2 family GO:0031224//intrinsic to membrane GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process;GO:0048232//male gamete generation 40267 1477.00 1.105 4.175 1.91772982796998 Up 0.576707172104081 mag magro K01046|1|9e-79|294|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|3|5e-71|268|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - - GO:0044238//primary metabolic process 38840 1455.00 1.185 0.17 -2.80128040764792 Down 0.403579447893277 Cyp316a1 Cyp316a1 K00517|1|0.0|949|dme:Dmel_CG8540| [EC:1.14.-.-] - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 37384 2340.58 90.875 93.365 0.0389983651026657 Up 0.133172632413155 RIC-3 RIC-3, isoform V - - - - 43656 1965.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 tll tailless K08545|1|0.0|814|dme:Dmel_CG1378|nuclear receptor subfamily 2 group E member 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0035270//endocrine system development;GO:0007049//cell cycle;GO:0009880//embryonic pattern specification;GO:0048598//embryonic morphogenesis;GO:0010468//regulation of gene expression;GO:0045165//cell fate commitment;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009798//axis specification;GO:0048103//somatic stem cell division;GO:0006351//transcription, DNA-dependent 37882 2817.00 5.635 6.89 0.29008837253207 Up 0.300521727644961 nord nord - GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 40167 2472.48 15.985 20.91 0.387474317809059 Up 0.499108440100383 Papss PAPS synthetase, isoform H K13811|1|0.0|1245|dme:Dmel_CG8363|3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] - GO:0016301//kinase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032559;GO:0016301//kinase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032559;GO:0016301//kinase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032559;GO:0016301//kinase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032559;GO:0016301//kinase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032559;GO:0016301//kinase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032559 GO:0006790//sulfur compound metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006790//sulfur compound metabolic process 36439 2778.00 0.315 0.705 1.16227142889888 Up 0.22173424910844 CG13326 CG13326 - - - - 41272 1621.00 13.095 13.215 0.0131603652909735 Up 0.0563994188350284 Cyp12e1 Cyp12e1 K00517|1|7e-117|421|dme:Dmel_CG11821| [EC:1.14.-.-];K10723|5|1e-46|187|dme:Dmel_CG13478|CYP314A1; ecdysone 20-monooxygenase [EC:1.14.99.22] - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 32955 1263.54 234.115 187.86 -0.317559458124751 Down 0.548672566371681 CG14207 CG14207, isoform D K09542|1|6e-18|92.0|bfo:BRAFLDRAFT_130908|crystallin, alpha B;K04455|2|1e-16|87.4|cin:100177240|heat shock 27kDa protein 1 - - GO:0006950//response to stress;GO:0006950//response to stress 37281 2041.00 7.83 4.585 -0.772090573695986 Down 0.52027473253203 CG11044 CG11044 K10314|1|0.0|1014|dme:Dmel_CG11044|F-box protein 39 - - - 34695 2445.00 1.18 1.8 0.609210046967833 Up 0.248547087570995 Vha68-3 vacuolar H[+] ATPase 68kD subunit 3 K02145|1|0.0|1477|dme:Dmel_CG5075|V-type H+-transporting ATPase subunit A [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport 318071 891.00 43.595 156.975 1.84830022836629 Up 0.780048870690794 CG32523 CG32523 K01362|1|2e-37|155|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|2e-27|122|dpo:Dpse_GA11574|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40252 1663.75 8.37 9.8 0.227554126452227 Up 0.294214766873597 CG33969 CG33969, isoform C K10262|1|0.0|841|dme:Dmel_CG33969|F-box and WD-40 domain protein 4 GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0016301//kinase activity;GO:0032559 GO:0007472//wing disc morphogenesis;GO:0009108//coenzyme biosynthetic process;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0051301//cell division;GO:0055088//lipid homeostasis 44289 3325.45 89.305 103.935 0.218868705876367 Up 0.436369039756967 flw flapwing, isoform C K06269|1|0.0|760|der:Dere_GG18356|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006810//transport;GO:0009888//tissue development;GO:0005980//glycogen catabolic process;GO:0043409//negative regulation of MAPK cascade;GO:0002164//larval development;GO:0005978//glycogen biosynthetic process;GO:0006464//cellular protein modification process;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation;GO:0006810//transport;GO:0009888//tissue development;GO:0043409//negative regulation of MAPK cascade;GO:0002164//larval development;GO:0006006//glucose metabolic process;GO:0006464//cellular protein modification process;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation 34390 1367.49 1.41 2.335 0.727727387310868 Up 0.313333773609827 CG4995 CG4995, isoform D K03454|1|4e-58|225|cel:C54G10.4|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 48224 818.41 24.135 15.46 -0.642586507519755 Down 0.608539162594109 Aprt adenine phosphoribosyltransferase, isoform D K00759|1|3e-83|308|dme:Dmel_CG18315|adenine phosphoribosyltransferase [EC:2.4.2.7] GO:0044424//intracellular part GO:0016763//transferase activity, transferring pentosyl groups GO:0043096//purine nucleobase salvage 40096 1253.78 8.18 7.86 -0.0575715306831423 Down 0.104345528992207 CG9666 CG9666, isoform D K07579|1|3e-121|434|dme:Dmel_CG9666|putative methylase - GO:0005488//binding;GO:0008168//methyltransferase activity;GO:0005488//binding;GO:0016741 GO:0006730//one-carbon metabolic process;GO:0006730//one-carbon metabolic process 31805 1165.00 5.785 6.655 0.202121706804402 Up 0.228536520935147 Ppt1 Palmitoyl-protein thioesterase 1, isoform B K01074|1|7e-172|603|dme:Dmel_CG12108|palmitoyl-protein thioesterase [EC:3.1.2.22] GO:0000323//lytic vacuole GO:0016790//thiolester hydrolase activity GO:0010259//multicellular organismal aging;GO:0006464//cellular protein modification process 42160 3768.07 7.72 5.225 -0.563169810299836 Down 0.454662528067626 htl heartless, isoform C K05094|1|0.0|1323|dme:Dmel_CG7223|fibroblast growth factor receptor 3 [EC:2.7.10.1];K04362|2|0.0|1027|dpo:Dpse_GA20192|fibroblast growth factor receptor 1 [EC:2.7.10.1];K13338|3|0.0|636|dmo:Dmoj_GI13761|peroxin-1;K05093|5|6e-175|615|dme:Dmel_CG32134|fibroblast growth factor receptor 2 [EC:2.7.10.1] - - - 46717 1243.00 7.815 5.22 -0.58219606642978 Down 0.463247919693568 arg arginase K01476|1|0.0|674|dme:Dmel_CG18104|arginase [EC:3.5.3.1] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0006527//arginine catabolic process 32293 1969.91 102.69 122.51 0.254603817263328 Up 0.471536124686303 Rbp1-like Rbp1-like, isoform C K12896|1|2e-26|121|tca:657225|splicing factor, arginine/serine-rich 7 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000245//spliceosomal complex assembly;GO:0000245//spliceosomal complex assembly 39924 1503.00 0.625 1.275 1.02856915219677 Up 0.28348302734117 CG6497 CG6497, isoform B - - - - 326114 1627.00 0.445 0.52 0.224706287174695 Up 0.0774996697926298 PH4alphaNE3 prolyl-4-hydroxylase-alpha NE3 K00472|1|0.0|990|dme:Dmel_CG31017|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 34955 1083.00 3.64 3.855 0.082792409716338 Up 0.0936137894597807 CG4935 CG4935 K13124|1|2e-180|631|dme:Dmel_CG4935|mitogen-activated protein kinase organizer 1 GO:0005681//spliceosomal complex GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0030908//protein splicing;GO:0000377 33005 4304.67 25.105 30.845 0.29706192126266 Up 0.468267071721041 Nep3 neprilysin 3, isoform C K01415|1|0.0|1624|dme:Dmel_CG9565|endothelin-converting enzyme [EC:3.4.24.71] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42213 857.00 0.37 0.565 0.610725596786238 Up 0.135748249900938 cona corona - GO:0000794//condensed nuclear chromosome - GO:0007127//meiosis I 31341 2853.62 10.255 13.485 0.395028029755752 Up 0.456874917448157 CG2930 CG2930, isoform F K03305|1|7e-164|578|tca:661253|proton-dependent oligopeptide transporter, POT family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0015833//peptide transport;GO:0015833//peptide transport;GO:0015833//peptide transport 34801 1092.00 1.34 2.05 0.613390909047674 Up 0.266708492933562 CG7953 CG7953, isoform B - - - - 14462776 434.00 92.01 48.59 -0.92113123487089 Down 0.712191256108836 CG44140 CG44140 - - - - 3772183 1897.92 3.365 6.59 0.969671960397735 Up 0.536223748514067 CG10096 CG10096, isoform B K13356|1|6e-86|320|aga:AgaP_AGAP011736|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 39405 1968.00 8.02 6.83 -0.23171665816483 Down 0.273774930656452 CG4328 CG4328 K09371|1|0.0|658|dpo:Dpse_GA18112|LIM homeobox transcription factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006909//phagocytosis;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent 19835032 2376.00 7.235 8.295 0.197248964424139 Up 0.249339585259543 261613 2037.69 23.875 18.55 -0.364081546302308 Down 0.494881785761458 CG31908 CG31908, isoform C - - - - 34581 1091.00 0.04 0.055 0.459431618637297 Up 0.0547483819838859 spag4 sperm-associated antigen 4 - - - - 40957 1879.00 7.7 1.25 -2.62293035092018 Down 0.696803592656188 CG7900 CG7900 K01426|1|0.0|650|dpo:Dpse_GA20671|amidase [EC:3.5.1.4];K01175|4|3e-12|73.6|ecb:100051756| [EC:3.1.-.-] - GO:0016879//ligase activity, forming carbon-nitrogen bonds - 42432 1582.00 2.07 2.715 0.391321430305036 Up 0.234150046229032 CG10877 CG10877 K01796|1|4e-38|159|mcc:698365|alpha-methylacyl-CoA racemase [EC:5.1.99.4] - GO:0003824//catalytic activity - 32147 1491.00 20.65 16.79 -0.298539551369778 Down 0.43663320565315 CG10352 CG10352 - - - - 39424 1128.45 17.88 28.185 0.656580830957894 Up 0.62303526614714 CG10638 CG10638, isoform D K00011|1|2e-83|309|dme:Dmel_CG10863|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process 39537 2741.69 20.47 18.81 -0.122011253500215 Down 0.236758684453837 CG32137 CG32137, isoform B K10352|1|5e-14|80.1|cin:100176948|myosin heavy chain - - - 50209 310.74 1088.785 769.93 -0.499919905471251 Down 0.648758420287941 IM3 immune induced molecule 3, isoform B - - - - 34379 713.00 0.45 0.895 0.991962680934582 Up 0.227545898824462 Hand hand K09071|1|3e-98|356|dme:Dmel_CG18144|heart-and neural crest derivatives-expressed protein GO:0043231//intracellular membrane-bounded organelle - GO:0035270//endocrine system development;GO:0003015//heart process;GO:0010468//regulation of gene expression;GO:0009887//organ morphogenesis;GO:0030855//epithelial cell differentiation;GO:0035051//cardiocyte differentiation 50252 3563.28 1.15 1.04 -0.145050332803283 Down 0.0827829877162858 CG30377 CG30377, isoform B - - - - 14462569 921.00 0.61 0.235 -1.37614848588525 Down 0.225366530180954 42367 1588.00 10718.05 13881.96 0.373168825650955 Up 0.590509840179633 ninaE neither inactivation nor afterpotential E K13802|1|0.0|743|der:Dere_GG15786|opsin Rh1 GO:0005790//smooth endoplasmic reticulum;GO:0016028//rhabdomere;GO:0005764//lysosome;GO:0005770//late endosome;GO:0031224//intrinsic to membrane;GO:0031410//cytoplasmic vesicle GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007626//locomotory behavior;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0050953//sensory perception of light stimulus;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0009416//response to light stimulus;GO:0042051//compound eye photoreceptor development 36565 1386.77 101.37 104.2 0.0397245212809127 Up 0.13403117157575 Tango7 transport and golgi organization 7, isoform B K03039|1|2e-07|57.8|cel:T06D8.8|26S proteasome regulatory subunit N9;K12180|2|4e-07|56.6|api:100159984|COP9 signalosome complex subunit 7 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding GO:0010467//gene expression;GO:0006996//organelle organization;GO:0015031//protein transport 317942 731.00 0.67 0.77 0.200697350237129 Up 0.0821555937128517 CG32259 CG32259, isoform D - - - - 19835923 481.00 8.865 9.57 0.110398293587337 Up 0.17250033020737 33486 2212.20 23.425 23.705 0.0171423451798461 Up 0.0753203011491217 CG3104 CG3104, isoform C K10380|1|8e-40|164|ecb:100055459|ankyrin - - - 36081 1154.00 0.135 0.12 -0.169925001442312 Down 0.0510500594373266 CG12911 CG12911, isoform F - - - - 42204 1643.57 6.48 5.815 -0.156214621411407 Down 0.191190067362304 CG31235 CG31235, isoform B K11161|1|1e-43|177|oaa:100078920|retinol dehydrogenase 13 [EC:1.1.1.-];K11153|5|4e-42|172|gga:423274|retinol dehydrogenase 12 [EC:1.1.1.-] - - - 2768677 1577.00 6.125 6.51 0.0879476992757024 Up 0.124455157839123 p53 p53, isoform E K10148|1|7e-22|105|tca:655327|tumor protein p73;K10149|2|3e-14|80.5|spu:756859|tumor protein p73-like;K04451|4|1e-10|68.6|xtr:431679|tumor protein p53 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009888//tissue development;GO:0051726//regulation of cell cycle;GO:0009416//response to light stimulus;GO:0010259//multicellular organismal aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032583;GO:0009888//tissue development;GO:0051726//regulation of cell cycle;GO:0009416//response to light stimulus;GO:0010259//multicellular organismal aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032583;GO:0009888//tissue development;GO:0051726//regulation of cell cycle;GO:0009416//response to light stimulus;GO:0010259//multicellular organismal aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032583 42824 5635.99 15.49 16.255 0.0695464119007877 Up 0.148989565447101 sba six-banded, isoform I - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 37213 744.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 CG18607 CG18607 K00669|1|1e-13|76.3|dme:Dmel_CG3318|arylalkylamine N-acetyltransferase [EC:2.3.1.87] - - - 12798219 2088.00 0.335 0.99 1.56326742962184 Up 0.30398890503236 326147 469.00 1.67 0.89 -0.907970861507654 Down 0.302635054814423 CG31515 CG31515 K03909|1|2e-08|57.8|mcc:613026|tissue factor pathway inhibitor;K06238|4|1e-07|55.1|oaa:100083924|collagen, type VI, alpha - GO:0004866//endopeptidase inhibitor activity - 31001 1732.62 10.83 10.725 -0.0140555952214192 Down 0.0555739004094571 CG4293 CG4293, isoform E - - - - 37638 1116.00 5.205 5.08 -0.0350696665272513 Down 0.0677255316338661 Gmer GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase K02377|1|1e-166|585|dme:Dmel_CG3495|GDP-L-fucose synthase [EC:1.1.1.271] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding GO:0050658//RNA transport;GO:0006005//L-fucose biosynthetic process 3772288 310.00 13.8 16.36 0.245504481276217 Up 0.366100911372342 CG33774 CG33774 - GO:0005789//endoplasmic reticulum membrane GO:0004576//oligosaccharyl transferase activity GO:0006486//protein glycosylation 246525 1007.00 7.245 1.03 -2.81434135237371 Down 0.699808479725267 CG30281 CG30281 K10104|1|3e-57|221|dwi:Dwil_GK15354|ficolin;K06252|3|2e-43|176|tgu:100221864|tenascin GO:0044421//extracellular region part GO:0005515//protein binding GO:0023060 35142 5207.02 15.965 14.845 -0.104935459583438 Down 0.194756306960771 CG10600 CG10600, isoform C - - - - 32727 1875.00 0.145 0.47 1.69660785655007 Up 0.211728965790516 p-cup presidents-cup - - - - 36655 1186.00 29 24.815 -0.224840445605177 Down 0.38693699643376 Ciao1 Ciao1 K01062|1|2e-26|120|cqu:CpipJ_CPIJ001448|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - - GO:0031163 46415 1276.69 558.225 500.985 -0.156079328361111 Down 0.371780478140272 Fer1HCH ferritin 1 heavy chain homologue, isoform J K00522|1|1e-93|207|dme:Dmel_CG2216|ferritin heavy chain [EC:1.16.3.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport 19835802 385.00 0.125 0.13 0.0565835283663675 Up 0.0422335226522256 37605 1011.00 0.01 0.515 5.68650052718322 Up 0.364020604939902 Obp59a Odorant-binding protein 59a - - GO:0005488//binding GO:0051234//establishment of localization 318958 3507.37 11.06 14.66 0.406533717899105 Up 0.472031435741646 CG31814 CG31814, isoform B K06774|1|1e-32|142|xla:444598|neurotrimin - - - 42708 1112.00 0.66 0.735 0.155278225477911 Up 0.0708955223880597 CG6660 CG6660 K00680|1|2e-159|561|dme:Dmel_CG6660| [EC:2.3.1.-];K10249|2|1e-46|186|isc:IscW_ISCW010886|elongation of very long chain fatty acids protein 4;K10250|4|7e-43|174|dre:327274|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane - - 5740599 1211.00 4.415 6.655 0.592025228263426 Up 0.441388191784441 pgc polar granule component, isoform D K11173|1|2e-91|336|dme:Dmel_CG3425|hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24] GO:0043232;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0043169//cation binding GO:0007276//gamete generation;GO:0003006//developmental process involved in reproduction;GO:0006350;GO:0006818//hydrogen transport;GO:0008152//metabolic process 33616 566.00 1.54 0.165 -3.22239242133645 Down 0.474375908070268 CG15423 CG15423 - - - - 41634 3145.00 0.455 0.555 0.28662122615141 Up 0.0890569277506274 CG8773 CG8773 K11141|1|0.0|1905|dme:Dmel_CG8773|glutamyl aminopeptidase [EC:3.4.11.7] - - - 50207 218.00 92.69 166.23 0.84269516783977 Up 0.710044908202351 CG15065 CG15065 - - - GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress 37190 4381.63 100.185 45.715 -1.13192699506547 Down 0.733753797384758 abba thin, isoform F K12035|1|0.0|999|dsi:Dsim_GD11426|tripartite motif-containing protein 71 - - - 33170 2619.38 22.88 23.925 0.0644318725949987 Up 0.151565182934883 CG4822 CG4822, isoform I K05679|1|2e-116|420|dre:556979|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 40893 1230.00 3.66 2.485 -0.558597796721756 Down 0.336712455422005 CG14598 CG14598 - - - - 41369 1936.34 15.21 24.21 0.67058292627444 Up 0.615011227050588 ninaG ninaG, isoform B K00115|1|4e-51|202|dme:Dmel_CG12539|glucose dehydrogenase (acceptor) [EC:1.1.99.10];K00108|2|5e-48|192|dpo:Dpse_GA21849|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0016101//diterpenoid metabolic process;GO:0051234//establishment of localization;GO:0050953//sensory perception of light stimulus;GO:0044281//small molecule metabolic process;GO:0042441//eye pigment metabolic process 39592 2305.32 1.435 1.01 -0.506695443923893 Down 0.199280147932902 shd shade, isoform D K10723|1|0.0|1032|dme:Dmel_CG13478|CYP314A1; ecdysone 20-monooxygenase [EC:1.14.99.22];K00517|3|1e-45|185|dme:Dmel_CG6042| [EC:1.14.-.-];K10721|5|5e-45|183|dpo:Dpse_GA11350|CYP302A1; ecdysteroid 22-hydroxylase GO:0043231//intracellular membrane-bounded organelle GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity GO:0048565//digestive tract development;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development;GO:0006694//steroid biosynthetic process;GO:0003006//developmental process involved in reproduction 43358 3123.00 4.61 5.35 0.214772140859171 Up 0.215427288337076 CG4849 CG4849 K12852|1|0.0|1932|dme:Dmel_CG4849|116 kDa U5 small nuclear ribonucleoprotein component GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding GO:0006412//translation;GO:0000377 19835151 4983.13 0.045 0.08 0.830074998557688 Up 0.0629375247655528 19835550 901.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 35802 1818.00 0.045 0.1 1.15200309344505 Up 0.0796790384361379 CG14760 CG14760 K09751|1|3e-24|113|mmu:319875|transmembrane protease, serine 11B [EC:3.4.21.-];K01320|2|2e-23|110|dre:114423|coagulation factor VII [EC:3.4.21.21];K09615|4|2e-22|107|hsa:25823|tryptase gamma 1 [EC:3.4.21.-];K01316|5|5e-22|105|oaa:100079480|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36852 1449.00 1.5 1.785 0.250961573533219 Up 0.137795535596355 CG4927 CG4927 K01320|1|2e-28|126|tgu:100223776|coagulation factor VII [EC:3.4.21.21];K01344|2|9e-28|124|xla:380116|protein C (activated) [EC:3.4.21.69];K09633|3|4e-26|119|oaa:100080302|transmembrane protease, serine 2 [EC:3.4.21.-];K01362|5|9e-26|118|dme:Dmel_CG4920| [EC:3.4.21.-] - - - 33306 1667.00 9.015 7.585 -0.249178311185308 Down 0.300686831330075 CG5126 CG5126 - - - - 41905 1881.00 0.305 0.455 0.57705730263581 Up 0.117157574957073 CG4525 CG4525 - - - - 36400 1210.00 29.305 23.265 -0.332985650241449 Down 0.490655131422533 CG8768 CG8768 K07071|1|7e-177|619|dme:Dmel_CG8768| - GO:0048037//cofactor binding GO:0008152//metabolic process 35230 1145.00 0.04 0.125 1.64385618977472 Up 0.101736890767402 CG13083 CG13083 K10352|1|4e-06|52.4|hmg:100205834|myosin heavy chain;K06674|2|4e-06|52.4|dre:321452|structural maintenance of chromosome 2 - - - 37187 1597.00 16.715 18.05 0.11085548215713 Up 0.215097080966847 prod proliferation disrupter - - - - 318020 1908.51 2.13 2.63 0.304209369066464 Up 0.195647866860388 CG42272 CG42272, isoform E - - - - 31528 1158.00 0.07 0.04 -0.807354922057604 Down 0.0629375247655528 CG6048 CG6048 K01362|1|1e-45|183|dpo:Dpse_GA13240| [EC:3.4.21.-];K01312|3|1e-36|154|dpo:Dpse_GA11599|trypsin [EC:3.4.21.4] - - - 35880 758.00 26.275 25.08 -0.0671534160475018 Down 0.1670519085986 MrgBP MrgBP K11343|1|2e-86|318|dme:Dmel_CG13746|MRG-binding protein GO:0000123//histone acetyltransferase complex - GO:0010468//regulation of gene expression 36077 1268.00 0.42 0.575 0.453172628165615 Up 0.117917051908599 CG12209 CG12209 - - - - 39725 746.42 52.105 44.275 -0.234929513301844 Down 0.427024171179501 CG18081 CG18081, isoform C - GO:0044464//cell part GO:0046914//transition metal ion binding - 32158 10349.56 22.9 32.615 0.510188030198995 Up 0.590047549861313 cac cacophony, isoform P K04851|1|0.0|1224|dre:403310|voltage-dependent calcium channel L type alpha-1D;K05315|4|0.0|1196|bmy:Bm1_39550|voltage-dependent calcium channel alpha 1, invertebrate GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0044456//synapse part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0008049//male courtship behavior;GO:0009584//detection of visible light;GO:0016192//vesicle-mediated transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0042044//fluid transport 5740831 661.00 0.305 0.275 -0.149377624038226 Down 0.0552767137762515 CG34167 CG34167 - - - - 3771862 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 2768670 4826.00 26.13 30.65 0.230179949258123 Up 0.398890503236032 dpr9 dpr9, isoform B K06774|1|6e-10|67.0|bta:534414|neurotrimin - - - 3885647 3512.37 21.795 19.335 -0.17278243927119 Down 0.310659093910976 Mitf mitf, isoform D K09455|1|2e-33|145|ssc:414902|microphthalmia-associated transcription factor - - - 38658 1911.00 0.01 0.315 4.97727992349992 Up 0.276482631092326 CG5568 CG5568 K01904|1|2e-40|167|cel:F11A3.1|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 36539 1481.00 10.415 11.79 0.178900878939116 Up 0.267930260203408 Uba3 ubiquitin activating enzyme 3 K10686|1|0.0|884|dme:Dmel_CG13343|ubiquitin-activating enzyme E1 C [EC:6.3.2.19] - GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559 GO:0032446//protein modification by small protein conjugation 40447 1229.11 1.455 1.995 0.455369593314062 Up 0.22104081363096 CG14561 CG14561, isoform B - - - - 43444 3510.78 6.345 6.645 0.0666490354350687 Up 0.104906881521596 CG14516 CG14516, isoform C K11140|1|0.0|1979|dme:Dmel_CG14516|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 318608 1319.00 2.05 0.645 -1.66825284408219 Down 0.432538634262317 CG31157 CG31157, isoform D - - GO:0000166//nucleotide binding - 39233 1594.00 9.555 11.045 0.209065640377818 Up 0.289492801479329 CG6321 CG6321 K00816|1|2e-23|110|oaa:100076580|kynurenine-oxoglutarate transaminase [EC:2.6.1.7];K00825|1|2e-23|110|oaa:100076580|2-aminoadipate transaminase [EC:2.6.1.39] - GO:0048037//cofactor binding;GO:0016740//transferase activity GO:0008152//metabolic process 53581 3540.49 26.815 30.725 0.196372757236424 Up 0.366332056531502 Gclc Glutamate-cysteine ligase catalytic subunit, isoform D K11204|1|0.0|1289|dme:Dmel_CG2259|glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016881//acid-amino acid ligase activity;GO:0005488//binding;GO:0016881//acid-amino acid ligase activity GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process 326157 5806.00 22.2 24.335 0.132473098041034 Up 0.263274336283186 mon2 mon2, isoform C - - - GO:0006810//transport 246640 3071.84 0.315 0.11 -1.51784830486262 Down 0.158730682868842 CG30480 CG30480, isoform B - - - - 42953 1435.64 20.82 32.325 0.6346803013982 Up 0.624224012679963 Ude Uracil-DNA degrading factor, isoform D - - - - 34383 1374.39 126.205 95.67 -0.399630564838733 Down 0.589981508387267 CG5390 CG5390, isoform B K01312|1|3e-35|149|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09751|2|9e-33|141|bta:528256|transmembrane protease, serine 11B [EC:3.4.21.-];K09614|4|5e-32|139|dme:Dmel_CG2105|corin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19836203 2160.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 33448 1144.00 0.04 0.04 0 - 0.0382380134724607 CG9962 CG9962 K02218|1|5e-79|294|cel:C03C10.1|casein kinase 1 [EC:2.7.11.1];K08957|2|1e-78|293|nve:NEMVE_v1g161273|casein kinase 1, alpha [EC:2.7.11.1] GO:0005815//microtubule organizing center GO:0004672//protein kinase activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0040009//regulation of growth rate;GO:0009790//embryo development;GO:0006464//cellular protein modification process 40046 7795.83 8.095 7.42 -0.125611893681763 Down 0.18095363888522 CG14073 CG14073, isoform C K10683|1|3e-15|85.9|isc:IscW_ISCW006139|BRCA1-associated RING domain protein 1 [EC:6.3.2.19] GO:0005819//spindle - GO:0007450//dorsal/ventral pattern formation, imaginal disc 43453 4086.27 63.92 74.115 0.21349814824069 Up 0.417250033020737 CG14509 CG14509, isoform E - - - - 318986 718.00 0.885 1.11 0.326810316267108 Up 0.13033284902919 t-cup tetleys-cup - - GO:0005506//iron ion binding - 36303 669.86 2.31 3.8 0.71810656691489 Up 0.390106987187954 CG8407 CG8407, isoform B K10412|1|2e-40|165|dya:Dyak_GE12408|dynein light chain 4, axonemal GO:0005875//microtubule associated complex;GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0003774//motor activity GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 42894 1762.84 27.31 25.95 -0.0736947755200433 Down 0.170849293356228 CG6364 CG6364, isoform E K00876|1|3e-176|617|dme:Dmel_CG6364|uridine kinase [EC:2.7.1.48] - GO:0019206//nucleoside kinase activity;GO:0032559;GO:0019206//nucleoside kinase activity;GO:0032559 GO:0006909//phagocytosis;GO:0006909//phagocytosis 33441 1610.62 1.93 1.905 -0.0188098497747585 Down 0.046559239202219 insv insensitive, isoform B - - - - 43575 1032.00 10.79 11.39 0.0780728822200951 Up 0.144597807423062 CG15528 CG15528 K04459|1|5e-122|437|dsi:Dsim_GD17377|dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 32482 1819.99 44.79 48.985 0.129163374083225 Up 0.292332584863294 CG6340 CG6340, isoform F K02087|1|1e-12|74.7|ame:409590|cyclin-dependent kinase 1 [EC:2.7.11.22] - - - 32028 10417.45 7.17 5 -0.520045024039818 Down 0.426132611279884 Myo10A myosin 10A, isoform F K10361|1|0.0|4752|dme:Dmel_CG2174|myosin XV GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 14462537 901.48 0.52 0.54 0.0544477840223765 Up 0.0451063267732136 CG44102 CG44102, isoform C - - - - 261607 1836.15 12.425 17.81 0.51944166465197 Up 0.544842160877031 CG32174 CG32174, isoform D - GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0007472//wing disc morphogenesis;GO:0044267//cellular protein metabolic process;GO:0048592//eye morphogenesis;GO:0006743//ubiquinone metabolic process;GO:0015781//pyrimidine nucleotide-sugar transport;GO:0007365//periodic partitioning;GO:0006743//ubiquinone metabolic process 39581 3746.88 2.845 2.775 -0.0359408810691135 Down 0.0579183727380795 stwl stonewall, isoform C - - GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0007293//germarium-derived egg chamber formation;GO:0051276//chromosome organization;GO:0010468//regulation of gene expression;GO:0019827//stem cell maintenance;GO:0033036 42078 983.00 5.87 7.23 0.300635143841066 Up 0.314621582353718 CG5285 CG5285 K10800|1|6e-165|579|dme:Dmel_CG5285|single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] - - - 59140 1336.00 0.175 0.07 -1.32192809488736 Down 0.114747061154405 CG18744 CG18744 - - - - 35801 2463.52 44.055 46.265 0.0706154244799203 Up 0.183331131950865 pnut peanut, isoform B K04557|1|1e-91|338|xtr:100125069|peanut-like protein 1 (cell division control related protein 1) GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0032156;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0044459//plasma membrane part;GO:0032156 GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0015631//tubulin binding GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0006915//apoptotic process;GO:0048278//vesicle docking;GO:0001751//compound eye photoreceptor cell differentiation;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0006915//apoptotic process;GO:0048278//vesicle docking;GO:0001751//compound eye photoreceptor cell differentiation 32864 2230.00 7.265 7.095 -0.0341601135722898 Down 0.0722493726059966 CCKLR-17D3 Cholecystokinin-like receptor at 17D3 K04196|1|0.0|787|dme:Dmel_CG32540|cholecystokinin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 3885640 587.00 2.26 2.22 -0.0257630960650815 Down 0.0499603751155726 CG34001 CG34001, isoform C K11270|1|1e-80|298|dme:Dmel_CG34001|chromosome transmission fidelity protein 8 - - - 14462662 403.00 0.01 0.4 5.32192809488736 Up 0.31904636111478 40950 7183.53 38.275 40.135 0.0684585198795149 Up 0.17979791308942 CG2747 CG2747, isoform F - - - - 43669 4387.51 5.25 6.61 0.332332848954207 Up 0.323239994716682 5-HT7 5-hydroxytryptamine (serotonin) receptor 7, isoform B K04164|1|0.0|871|dme:Dmel_CG12073|5-hydroxytryptamine (serotonin) receptor, invertebrate GO:0016021//integral to membrane GO:0008227//G-protein coupled amine receptor activity GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway 14462486 5507.00 12.52 12.275 -0.0285115377305629 Down 0.0799762250693435 CG43732 CG43732 - - - - 33354 3249.10 36.185 46.475 0.36106309353699 Up 0.537346453572844 CG17646 CG17646, isoform B K05679|1|5e-117|422|mmu:11307|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559 - 41087 3017.68 38.27 34.205 -0.16200667098427 Down 0.327697794214767 Rel relish, isoform D K09255|1|0.0|1826|dme:Dmel_CG11992|Rel/ankyrin family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007166//cell surface receptor signaling pathway;GO:0048666//neuron development;GO:0002812;GO:0031328//positive regulation of cellular biosynthetic process;GO:0002783;GO:0002252;GO:0023060;GO:0010551;GO:0031349//positive regulation of defense response;GO:0009267//cellular response to starvation;GO:0007166//cell surface receptor signaling pathway;GO:0048666//neuron development;GO:0002812;GO:0031328//positive regulation of cellular biosynthetic process;GO:0002783;GO:0002252;GO:0023060;GO:0010551;GO:0031349//positive regulation of defense response;GO:0009267//cellular response to starvation;GO:0007166//cell surface receptor signaling pathway;GO:0048666//neuron development;GO:0002812;GO:0031328//positive regulation of cellular biosynthetic process;GO:0002783;GO:0002252;GO:0023060;GO:0010551;GO:0031349//positive regulation of defense response;GO:0009267//cellular response to starvation;GO:0007166//cell surface receptor signaling pathway;GO:0048666//neuron development;GO:0002812;GO:0031328//positive regulation of cellular biosynthetic process;GO:0002783;GO:0002252;GO:0023060;GO:0010551;GO:0031349//positive regulation of defense response;GO:0009267//cellular response to starvation 43411 2099.00 6.85 3.44 -0.993695423145791 Down 0.545040285299168 CG14523 CG14523 K01415|1|3e-92|339|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|3e-44|180|dmo:Dmoj_GI16188|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41219 2971.05 6.54 7.86 0.265238676760524 Up 0.300026416589618 Art4 arginine methyltransferase 4, isoform B K05931|1|0.0|1036|dme:Dmel_CG5358|histone-arginine methyltransferase CARM1 [EC:2.1.1.125] GO:0043231//intracellular membrane-bounded organelle;GO:0034708 GO:0016274//protein-arginine N-methyltransferase activity GO:0016568//chromatin modification;GO:0010468//regulation of gene expression;GO:0035075//response to ecdysone;GO:0035247//peptidyl-arginine omega-N-methylation 32850 3200.45 38.41 39.255 0.031394461238126 Up 0.104411570466253 Rip11 Rab11 interacting protein, isoform E K12484|1|0.0|671|dme:Dmel_CG6606|Rab11 family-interacting protein 1/2/5 GO:0043227//membrane-bounded organelle;GO:0043227//membrane-bounded organelle - GO:0006810//transport;GO:0042051//compound eye photoreceptor development;GO:0006810//transport;GO:0042051//compound eye photoreceptor development 34409 1939.15 4.62 3.54 -0.38414349133306 Down 0.300785893541144 gny garnysstan, isoform B K03848|1|0.0|834|dme:Dmel_CG5091|alpha-1,3-glucosyltransferase [EC:2.4.1.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0016758//transferase activity, transferring hexosyl groups GO:0006486//protein glycosylation 3771732 1540.15 0.775 0.51 -0.603699063302742 Down 0.154834235900145 - CG30461, isoform K - - - - 34831 4524.87 77.58 56.55 -0.456157751654228 Down 0.608043851538766 smi35A Dual-specificity tyrosine phosphorylation-regulated kinase 2, isoform G K08825|1|0.0|1094|dme:Dmel_CG4551|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase [EC:2.7.12.1] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0007635//chemosensory behavior;GO:0006464//cellular protein modification process;GO:0007635//chemosensory behavior;GO:0006464//cellular protein modification process;GO:0007635//chemosensory behavior;GO:0006464//cellular protein modification process;GO:0007635//chemosensory behavior;GO:0006464//cellular protein modification process;GO:0007635//chemosensory behavior 36752 2108.00 14.99 7.725 -0.956393545156123 Down 0.631785761458196 Cyp4aa1 Cyp4aa1 K00517|1|0.0|967|dme:Dmel_CG8302| [EC:1.14.-.-];K07427|3|4e-76|286|xtr:780124|cytochrome P450, family 4, subfamily V - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding - 34135 1577.82 32.41 32.13 -0.0125180398464285 Down 0.0634658565579184 Scgalpha sarcoglycan alpha, isoform C K12565|1|1e-19|98.2|oaa:100087291|alpha-sarcoglycan GO:0016011//dystroglycan complex GO:0046872//metal ion binding;GO:0005198//structural molecule activity - 39548 865.00 3.84 3.09 -0.313499472816782 Down 0.242273147536653 CG17361 CG17361 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 36873 501.03 37.17 40.295 0.116462145026835 Up 0.268062343151499 Acp53C14b accessory gland protein 53C14b, isoform B - - - - 19835748 647.00 0.065 0.145 1.15754127698648 Up 0.0982366926429798 33941 2303.28 78.075 61.89 -0.335154342300295 Down 0.543653414344208 Tsp thrombospondin, isoform H K04659|1|0.0|739|cqu:CpipJ_CPIJ011343|thrombospondin GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding GO:0007155//cell adhesion;GO:0048513//organ development;GO:0007155//cell adhesion;GO:0048513//organ development;GO:0007155//cell adhesion;GO:0048513//organ development;GO:0007155//cell adhesion;GO:0048513//organ development;GO:0007155//cell adhesion;GO:0048513//organ development;GO:0007155//cell adhesion;GO:0048513//organ development 19835792 346.00 0.01 0.99 6.62935662007961 Up 0.499141460837406 40872 1185.37 7.775 7.305 -0.0899584022144665 Down 0.137003037907806 CG1227 CG1227, isoform B K08856|1|0.0|642|dme:Dmel_CG1227|serine/threonine kinase 16 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 41952 7366.33 32.39 36.99 0.191586832328808 Up 0.365671641791045 msps mini spindles, isoform F - GO:0005815//microtubule organizing center GO:0015631//tubulin binding GO:0007126//meiosis;GO:0000741//karyogamy;GO:0007308//oocyte construction;GO:0000087//M phase of mitotic cell cycle;GO:0007052//mitotic spindle organization 39415 3050.11 56.61 58.02 0.0354933718763961 Up 0.127757231541408 CG32103 CG32103, isoform E K05863|1|2e-27|125|bfo:BRAFLDRAFT_280633|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0005215//transporter activity;GO:0046872//metal ion binding;GO:0005215//transporter activity;GO:0046872//metal ion binding;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 42729 1617.57 0.235 0.6 1.35230174393088 Up 0.217936864350812 CG17110 CG17110, isoform C K01436|1|0.0|793|dme:Dmel_CG17110|aminoacylase [EC:3.5.1.14] GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding GO:0006519 246462 2052.00 0.205 0.575 1.48793804632629 Up 0.22381455554088 CG30110 CG30110 - - - - 5740485 1266.00 26.985 29.675 0.13709034255663 Up 0.287643640206049 41810 1265.00 0.97 1.615 0.735477512506797 Up 0.263802668075551 CG14861 CG14861 - - - - 31118 3161.00 8.095 8.395 0.052499244634464 Up 0.0974772156914542 dor deep orange - - - - 35122 1216.00 1.775 1.035 -0.778188256892719 Down 0.286686038832387 CG10336 CG10336, isoform C K10904|1|9e-156|549|dme:Dmel_CG10336|TIMELESS-interacting protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0045005//maintenance of fidelity involved in DNA-dependent DNA replication;GO:0033554//cellular response to stress;GO:0045005//maintenance of fidelity involved in DNA-dependent DNA replication;GO:0033554//cellular response to stress 44642 8441.00 19.28 21.915 0.184813627294693 Up 0.323339056927751 Apc APC-like, isoform B K02085|1|0.0|4128|dme:Dmel_CG1451|adenomatosis polyposis coli protein GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0032155;GO:0044459//plasma membrane part GO:0015631//tubulin binding GO:0044260;GO:0080090//regulation of primary metabolic process;GO:0048699//generation of neurons;GO:0007155//cell adhesion;GO:0016055//Wnt receptor signaling pathway;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0031323//regulation of cellular metabolic process;GO:0030902//hindbrain development;GO:0008363//larval chitin-based cuticle development;GO:0003002//regionalization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0035466;GO:0007293//germarium-derived egg chamber formation;GO:0060255 246587 1134.08 31.405 28.945 -0.117680112771261 Down 0.258651433099987 CG30392 CG30392, isoform B - GO:0044424//intracellular part GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0006869//lipid transport 36727 1604.00 20.665 21.12 0.0314204709839134 Up 0.095330867784969 Cdk5 Cyclin-dependent kinase 5 K02090|1|2e-170|598|dya:Dyak_GE14145|cyclin-dependent kinase 5 [EC:2.7.11.22] GO:0030427//site of polarized growth;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0031252//cell leading edge;GO:0043232;GO:0045202//synapse;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0032559;GO:0030546//receptor activator activity GO:0007172//signal complex assembly;GO:0007270//neuron-neuron synaptic transmission;GO:0009057//macromolecule catabolic process;GO:0014037//Schwann cell differentiation;GO:0048167//regulation of synaptic plasticity;GO:0007411//axon guidance;GO:0030534//adult behavior;GO:0051899//membrane depolarization;GO:0043065//positive regulation of apoptotic process;GO:0021543//pallium development;GO:0014706//striated muscle tissue development;GO:0016567//protein ubiquitination;GO:0015031//protein transport;GO:0010259//multicellular organismal aging;GO:0051726//regulation of cell cycle;GO:0001505//regulation of neurotransmitter levels;GO:0033674//positive regulation of kinase activity;GO:0016477//cell migration;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0007600//sensory perception;GO:0007612//learning;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0042501//serine phosphorylation of STAT protein;GO:0006897//endocytosis;GO:0031589//cell-substrate adhesion;GO:0021953//central nervous system neuron differentiation;GO:0046823;GO:0007632//visual behavior;GO:0030036//actin cytoskeleton organization;GO:0006950//response to stress;GO:0021549//cerebellum development;GO:0014073 3771960 5450.00 2.88 3.065 0.0898182622484692 Up 0.0906419231277242 waw waclaw K03596|1|0.0|664|nve:NEMVE_v1g106275|GTP-binding protein LepA;K03234|2|5e-26|121|dme:Dmel_CG33158|elongation factor EF-2 [EC:3.6.5.3] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006351//transcription, DNA-dependent 19834833 641.00 0.9 0.91 0.0159415438690215 Up 0.0413749834896315 - CG45488 - - - - 35692 907.86 55.365 35.355 -0.647059978995441 Down 0.653414344208163 CG30499 CG30499, isoform B K01783|1|3e-119|427|dsi:Dsim_GD10239|ribulose-phosphate 3-epimerase [EC:5.1.3.1] - GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives GO:0044238//primary metabolic process 41740 3328.43 8.585 7.455 -0.203609781718692 Down 0.256439043719456 su(Hw) suppressor of hairy wing, isoform C K09228|1|2e-57|224|api:100159445|KRAB domain-containing zinc finger protein - - - 42239 1446.00 4.68 4.51 -0.0533810963280236 Down 0.0784572711662924 CstF-64 cleavage stimulation factor 64 kilodalton subunit K13107|1|7e-14|79.0|hmg:100204213|RNA-binding motif protein, X-linked 2 GO:0005849//mRNA cleavage factor complex GO:0003723//RNA binding GO:0006397//mRNA processing 19835262 496.79 112.84 117.17 0.0543246609123474 Up 0.155857878747854 - CG45089, isoform C - - - - 43449 3346.99 69.815 42.9 -0.702559390152596 Down 0.671476687359662 Rpn2 regulatory particle non-ATPase 2, isoform C K03032|1|0.0|1781|dme:Dmel_CG11888|26S proteasome regulatory subunit N2 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0009894;GO:0033554//cellular response to stress 32120 2387.69 65.085 66.905 0.0397889447032719 Up 0.130729097873465 PhKgamma phosphorylase kinase gamma, isoform H K00871|1|0.0|884|dme:Dmel_CG1830|phosphorylase kinase gamma subunit [EC:2.7.11.19] GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0032559;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0032559;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0032559 GO:0009653//anatomical structure morphogenesis;GO:0005977//glycogen metabolic process;GO:0006464//cellular protein modification process;GO:0009653//anatomical structure morphogenesis;GO:0005977//glycogen metabolic process;GO:0006464//cellular protein modification process;GO:0009653//anatomical structure morphogenesis;GO:0005977//glycogen metabolic process;GO:0006464//cellular protein modification process 36299 2474.00 7.61 7.92 0.0576039765760644 Up 0.103420948355567 CG8378 CG8378 K11426|1|2e-09|64.7|nve:NEMVE_v1g214071|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006350 48986 704.00 32.8 37.02 0.174609080365128 Up 0.341005151234976 boca boca - GO:0044432//endoplasmic reticulum part - GO:0007292//female gamete generation;GO:0048193//Golgi vesicle transport;GO:0007166//cell surface receptor signaling pathway;GO:0043112//receptor metabolic process;GO:0006605//protein targeting 38422 905.58 33.54 26.965 -0.314794655053786 Down 0.482994320433232 CG12012 CG12012, isoform C - - - - 19835330 955.00 1.71 1.325 -0.368003965435336 Down 0.177684585919958 33934 4057.43 0.69 2.115 1.61598939634178 Up 0.435279355435213 cup cup, isoform C - - - - 33194 1756.00 3.725 2.965 -0.32920832080352 Down 0.248084797252675 mbm mushroom body miniature - - - GO:0008344//adult locomotory behavior;GO:0007420//brain development 43081 2306.06 13.345 15.115 0.179681673485741 Up 0.290879672434289 CG5116 CG5116, isoform B - GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding - 35576 1415.18 37.28 38.51 0.0468312631427056 Up 0.141460837405891 Mob4 Mob4, isoform B K06685|1|7e-09|62.0|cin:100185307|maintenance of ploidy protein MOB1 (MPS1 binder 1) GO:0000139//Golgi membrane;GO:0005815//microtubule organizing center GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0051234//establishment of localization 3354987 3541.94 13.895 3.105 -2.16190066098008 Down 0.721602166160349 tyn trynity, isoform F - - - - 32848 6138.00 0.065 0.17 1.38702312310925 Up 0.115143309998679 CG15040 CG15040 K13168|1|6e-09|64.7|nvi:100169978|splicing factor, arginine/serine-rich 16;K10876|2|7e-09|64.3|der:Dere_GG19952|RAD54-like protein 2 [EC:3.6.1.-];K13172|4|2e-08|63.2|dmo:Dmoj_GI16794|serine/arginine repetitive matrix protein 2 - - GO:0043170 45039 2049.00 0.155 0.175 0.175086706558091 Up 0.0511161009113723 Sox100B Sox100B K09270|1|0.0|752|dme:Dmel_CG15552|transcription factor SOX7/8/9/10/18 (SOX group E/F) - - - 36277 1141.10 59.35 62.295 0.0698683426166821 Up 0.188812574296658 PI31 PI31, isoform F K06700|1|5e-151|533|dme:Dmel_CG8979|proteasome inhibitor subunit 1 (PI31) - - GO:0033554//cellular response to stress;GO:0033554//cellular response to stress;GO:0033554//cellular response to stress 47767 1979.88 654.6 507.65 -0.366779430761692 Down 0.589122969224673 crc cryptocephal, isoform F K04374|1|9e-16|85.9|ame:410226|activating transcription factor 4 GO:0044432//endoplasmic reticulum part;GO:0044432//endoplasmic reticulum part GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0007635//chemosensory behavior;GO:0018988;GO:0044267//cellular protein metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0007399//nervous system development;GO:0009605//response to external stimulus;GO:0007635//chemosensory behavior;GO:0018988;GO:0044267//cellular protein metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0007399//nervous system development;GO:0009605//response to external stimulus 32999 3953.00 0.205 0.43 1.06871275008401 Up 0.163221503103949 amn amnesiac - - GO:0005179//hormone activity GO:0007613//memory;GO:0006959//humoral immune response;GO:0045762//positive regulation of adenylate cyclase activity;GO:0030534//adult behavior;GO:0044057;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0042065;GO:0007619//courtship behavior;GO:0007186//G-protein coupled receptor signaling pathway 35007 6773.32 564.51 431.54 -0.387504846945265 Down 0.59916127327962 Mhc myosin heavy chain, isoform U K10352|1|0.0|3167|dme:Dmel_CG17927|myosin heavy chain GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0030017//sarcomere GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005198//structural molecule activity;GO:0032559 GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development;GO:0003012//muscle system process;GO:0014866//skeletal myofibril assembly;GO:0007424//open tracheal system development 39068 2899.00 0.17 0.675 1.98935275580049 Up 0.27304847444195 Klp67A Kinesin-like protein at 67A, isoform C K10401|1|0.0|1502|dme:Dmel_CG10923|kinesin family member 18/19 GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle GO:0003774//motor activity;GO:0032559 GO:0007080//mitotic metaphase plate congression;GO:0031109//microtubule polymerization or depolymerization;GO:0051301//cell division;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0007060//male meiosis chromosome segregation 37170 1797.08 118.32 107.585 -0.137217012872065 Down 0.328358208955224 CG15096 CG15096, isoform C K08193|1|7e-92|338|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|2|8e-91|334|bfo:BRAFLDRAFT_274979|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - - 2768690 1096.00 1.615 1.33 -0.280107919192735 Down 0.143343019416193 CG33346 CG33346 K01173|1|9e-06|51.2|mdo:100013530|endonuclease [EC:3.1.30.-] - GO:0043169//cation binding;GO:0003824//catalytic activity - 317973 732.00 1.08 1.49 0.464281018298693 Up 0.191817461365738 CG32313 CG32313, isoform C - - - - 31352 1876.00 0.205 0.33 0.686842114740369 Up 0.107977810064721 CG6414 CG6414 K03927|1|1e-87|323|api:100162163|carboxylesterase type B [EC:3.1.1.1];K01044|4|5e-70|265|dme:Dmel_CG9858|carboxylesterase [EC:3.1.1.1] - GO:0003824//catalytic activity - 40932 1293.00 60.17 65.435 0.121018156933741 Up 0.281798969753005 mRpS9 mitochondrial ribosomal protein S9 K02960|1|2e-08|60.1|bmy:Bm1_14095|small subunit ribosomal protein S16e GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 19836139 641.00 0.9 0.91 0.0159415438690215 Up 0.0413749834896315 - CG45494 - - - - 35596 2807.47 32.71 26.21 -0.319614405754361 Down 0.489928675208031 coro coro, isoform G K13882|1|2e-151|536|xtr:448298|coronin-1A;K13887|2|5e-150|532|ecb:100059852|coronin-1C GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton - - 39757 1980.17 5.47 5.63 0.0415940892876729 Up 0.0744617619865275 Taspase1 taspase 1, isoform B K08657|1|0.0|746|dme:Dmel_CG5241|taspase, threonine aspartase, 1 [EC:3.4.25.-] - GO:0016787//hydrolase activity - 32663 1834.00 8.59 11.33 0.399417824682052 Up 0.435873728701625 CG9609 CG9609 K09191|1|3e-34|146|mdo:100024994|general transcription factor IIIA;K09228|5|6e-34|145|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 34848 1017.07 4.065 4.35 0.0977600486610628 Up 0.112204464403645 CG4218 CG4218, isoform D - - - - 39558 5722.00 7.435 8.095 0.122698338250147 Up 0.173226786421873 blue bluestreak K01931|1|8e-178|625|nve:NEMVE_v1g208895|protein neuralized - - GO:0007017//microtubule-based process;GO:0019094//pole plasm mRNA localization 37218 2221.50 66.29 73.6 0.150914513418386 Up 0.334169858671246 endoB endophilin B, isoform D K11248|1|0.0|738|dya:Dyak_GE13854|endophilin-B - - - 41080 1575.00 22.41 23.075 0.0421879990227434 Up 0.114780081891428 CG11982 CG11982 K11982|1|0.0|642|dme:Dmel_CG11982|E3 ubiquitin-protein ligase RNF115/126 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 59163 1386.00 7.28 7.095 -0.0371357661381446 Down 0.0776317527407212 CG18787 CG18787 - - GO:0005488//binding - 7354455 820.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 33148 3693.18 17.575 16.665 -0.0767033718496495 Down 0.165499933958526 fog folded gastrulation, isoform F - - - GO:0065008;GO:0050793//regulation of developmental process;GO:0010004//gastrulation involving germ band extension;GO:0002009//morphogenesis of an epithelium;GO:0009880//embryonic pattern specification;GO:0065008;GO:0050793//regulation of developmental process;GO:0010004//gastrulation involving germ band extension;GO:0002009//morphogenesis of an epithelium;GO:0009880//embryonic pattern specification 40983 1063.00 4.715 3.79 -0.315059922504005 Down 0.268755778628979 tex tex K12880|1|0.0|662|dsi:Dsim_GD20876|THO complex subunit 3 - - - 41212 980.00 6.86 9.53 0.47426763773713 Up 0.448916919825651 CG16904 CG16904 K00680|1|1e-64|246|dme:Dmel_CG8534| [EC:2.3.1.-];K10249|5|6e-32|137|spu:593296|elongation of very long chain fatty acids protein 4 GO:0031224//intrinsic to membrane - - 40259 1373.00 28.45 30.97 0.122442730480719 Up 0.259609034473649 Las lipoic acid synthase K03644|1|0.0|771|dme:Dmel_CG5231|lipoic acid synthetase [EC:2.8.1.8] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016783//sulfurtransferase activity GO:0009105 326140 3038.41 13.775 12.135 -0.182878210307386 Down 0.28325188218201 CG31445 CG31445, isoform B K11140|1|0.0|1766|dsi:Dsim_GD17862|aminopeptidase N [EC:3.4.11.2] GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 34443 1553.00 22.705 29.465 0.375992229427273 Up 0.52212389380531 CG6144 CG6144, isoform C K10768|1|2e-121|436|dme:Dmel_CG6144|alkylated DNA repair protein alkB homolog 6 - GO:0003824//catalytic activity;GO:0003824//catalytic activity - 43369 503.00 0.98 0.46 -1.0911478880582 Down 0.254655923920222 CG17856 CG17856 K00417|1|1e-56|218|dme:Dmel_CG17856|ubiquinol-cytochrome c reductase subunit 7 [EC:1.10.2.2] GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity GO:0006979//response to oxidative stress;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain;GO:0017062//respiratory chain complex III assembly 19834782 1222.94 8.88 18.735 1.07710439597901 Up 0.66682076343944 34827 2150.00 0.17 0.105 -0.695145418471579 Down 0.0806696605468234 CG16879 CG16879, isoform B - - - - 35889 2119.00 1.41 1.25 -0.173767067736707 Down 0.0974441949544314 CG8247 spitting image - GO:0044424//intracellular part - GO:0007275//multicellular organismal development 35411 1583.00 309.84 259.605 -0.255205236524981 Down 0.492867520803064 Lamp1 Lamp1 K06528|1|1e-139|496|dme:Dmel_CG3305|lysosomal-associated membrane protein 1/2 - - - 35168 2188.00 19.16 21.61 0.173601511123327 Up 0.310328886540748 Side similar to deadpan K09090|1|6e-24|112|dsi:Dsim_GD14118|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0007411//axon guidance;GO:0006357//regulation of transcription from RNA polymerase II promoter 53433 1309.00 16.725 18.345 0.133380693719719 Up 0.245872407872144 Vhl von Hippel-Lindau, isoform B K03871|1|2e-92|339|dme:Dmel_CG13221|von Hippel-Lindau disease tumor supressor GO:0000153//cytoplasmic ubiquitin ligase complex GO:0005488//binding;GO:0019787//small conjugating protein ligase activity GO:0007019//microtubule depolymerization;GO:0007163//establishment or maintenance of cell polarity;GO:0032446//protein modification by small protein conjugation 35858 2645.00 0.105 0.085 -0.304854581528421 Down 0.053394531765949 CG14744 CG14744, isoform E K13754|1|0.0|1166|dme:Dmel_CG14744|solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 GO:0031224//intrinsic to membrane GO:0042578//phosphoric ester hydrolase activity GO:0006810//transport 37806 595.63 66.8 90.2 0.433279330781329 Up 0.598137630431911 CG13565 CG13565, isoform C - - - - 3355180 1377.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 Ppr-Y Ppr-Y K11293|1|5e-16|85.9|cel:K10D2.1|protein HIRA/HIR1;K01768|5|2e-14|80.5|mcc:700574|adenylate cyclase [EC:4.6.1.1] - - - 4379909 539.30 12.45 20.56 0.723694522238435 Up 0.616464139479593 BG642312 BG642312, isoform B - - - - 19834720 1073.00 0.85 0.89 0.0663424948286958 Up 0.0525359926033549 - CG44385 - - - - 34334 4130.00 0.12 0.125 0.0588936890535683 Up 0.0382380134724607 CG13131 CG13131 - - - - 34397 1356.26 28.8 26.45 -0.122801089328287 Down 0.256273940034342 Sps2 selenophosphate synthetase 2, isoform D K01008|1|3e-172|559|dme:Dmel_CG5025|selenide, water dikinase [EC:2.7.9.3] GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0046914//transition metal ion binding;GO:0032559;GO:0016301//kinase activity;GO:0032559 - 5740550 603.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG40948 CG40948 - - - - 32421 667.00 2.69 0.01 -8.07146236255662 Down 0.724474970281337 CG14406 CG14406, isoform B - - - - 38086 2193.00 3.385 2.455 -0.463432809260304 Down 0.289723946638489 CG13894 CG13894 - - GO:0003676//nucleic acid binding - 47906 3220.74 47.34 45.61 -0.0537095358768602 Down 0.147041341962753 Dek Dek, isoform E - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 36789 1148.00 8.515 8.595 0.0134911097995183 Up 0.0526350548144235 CG8435 CG8435 K13115|1|1e-15|84.3|cin:100175929|coiled-coil domain-containing protein 130 - - - 40061 892.00 5.195 5.255 0.0165670150579666 Up 0.0528001584995377 CG3893 asterix K02728|1|4e-10|65.1|ame:413757|20S proteasome subunit alpha 3 [EC:3.4.25.1] - - - 35585 565.24 43.98 43.2 -0.0258162918041372 Down 0.103751155725796 CG3420 CG3420, isoform B - GO:0043227//membrane-bounded organelle GO:0051536//iron-sulfur cluster binding - 36174 2321.96 12.655 10.6 -0.255643242660123 Down 0.348071588957866 CG7737 CG7737, isoform B K12259|1|2e-50|201|gga:422934|spermine oxidase [EC:1.5.3.16] - - - 43593 1733.00 24.495 20.955 -0.225192770152232 Down 0.382446176198653 CG9743 CG9743 K00507|1|0.0|846|dme:Dmel_CG9743|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] GO:0031224//intrinsic to membrane GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0006631//fatty acid metabolic process 31839 4736.93 41.025 38.69 -0.084542604957859 Down 0.199808479725267 CG7766 CG7766, isoform I K07190|1|0.0|2355|dya:Dyak_GE17417|phosphorylase kinase alpha/beta subunit - GO:0015926//glucosidase activity;GO:0019887//protein kinase regulator activity;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0015926//glucosidase activity;GO:0019887//protein kinase regulator activity;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0015926//glucosidase activity;GO:0019887//protein kinase regulator activity;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0015926//glucosidase activity;GO:0019887//protein kinase regulator activity;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006006//glucose metabolic process;GO:0006006//glucose metabolic process;GO:0006006//glucose metabolic process;GO:0006006//glucose metabolic process 33119 2197.96 1.925 1.925 -1.60171325190746e-16 Down 0.0382380134724607 mst misato, isoform B - GO:0032991//macromolecular complex GO:0032561//guanyl ribonucleotide binding GO:0043623//cellular protein complex assembly 37238 1596.70 425.28 424.72 -0.00190096315244326 Down 0.0470545502575618 betaTub56D beta-Tubulin at 56D, isoform B K07375|1|0.0|844|der:Dere_GG20906|tubulin beta - - - 37659 1460.00 6.85 7.1 0.0517150365441554 Up 0.0905758816536785 CG9890 CG9890 K11436|1|7e-07|55.5|tad:TRIADDRAFT_52302|protein arginine N-methyltransferase 3 [EC:2.1.1.-] GO:0044464//cell part GO:0046914//transition metal ion binding - 36186 485.00 274.695 120.415 -1.18981553205265 Down 0.749273543785497 CG34227 CG34227 - - - - 31461 1982.37 16.44 24.73 0.589051940708255 Up 0.59708096684718 CG15784 CG15784, isoform B - - - - 47399 3490.05 46.275 44.605 -0.0530275519033661 Down 0.146380927222296 Reph regulator of eph expression, isoform B - - - - 40431 2366.52 94.285 103.395 0.133066248285579 Up 0.310064720644565 CG7414 CG7414, isoform E K03253|1|1e-17|92.0|bfo:BRAFLDRAFT_131352|translation initiation factor eIF-3 subunit 9 GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part GO:0043021//ribonucleoprotein complex binding;GO:0004175//endopeptidase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0004175//endopeptidase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0004175//endopeptidase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0004175//endopeptidase activity;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0042254//ribosome biogenesis;GO:0006412//translation;GO:0042254//ribosome biogenesis;GO:0006412//translation;GO:0042254//ribosome biogenesis;GO:0006412//translation;GO:0042254//ribosome biogenesis 40712 3363.00 17.7 23.49 0.408297353041837 Up 0.51981244221371 sec8 Sec8 ortholog K06111|1|0.0|1815|dme:Dmel_CG2095|exocyst complex component 4 GO:0043234//protein complex - GO:0048278//vesicle docking 5740537 825.00 0.05 0.11 1.13750352374994 Up 0.0858869369964338 CG34302 CG34302 - - - - 37814 1454.00 34.255 23.855 -0.522022898794002 Down 0.596189406947563 Fmo-1 Flavin-containing monooxygenase 1 K00485|1|0.0|857|dme:Dmel_CG3006|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0042598;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0030554//adenyl nucleotide binding GO:0008152//metabolic process 19835253 3734.00 0.02 0.01 -1 Down 0.0497292299564126 36157 1025.00 11.89 12.83 0.109772455344027 Up 0.191091005151235 cag cag, isoform B K11496|1|4e-15|82.8|mdo:100031122|centromere protein B GO:0044427//chromosomal part GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression 317860 1841.00 19.98 22.82 0.191742208496263 Up 0.337240787214371 CG32112 CG32112, isoform E - - - - 5740386 642.00 0.815 0.535 -0.60726116782993 Down 0.162429005415401 CG40813 CG40813 - - GO:0005488//binding - 39005 337.00 3.345 4.07 0.283022583624786 Up 0.231277242108044 CG5804 CG5804 K08762|1|3e-11|66.2|xla:444376|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) - GO:0005504//fatty acid binding;GO:0008144//drug binding;GO:0030234//enzyme regulator activity - 40719 893.00 31.12 24.14 -0.36641638423117 Down 0.520010566635847 CG2046 CG2046 K11875|1|5e-18|91.7|ame:552102|proteasome assembly chaperone 1 - - - 42558 2786.00 0.04 0.065 0.700439718141092 Up 0.0550785893541144 CG42335 CG42335 K11140|1|2e-94|347|nvi:100124286|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 43118 1224.00 0.68 0.845 0.313416595031845 Up 0.110784572711663 CG17770 CG17770 K02183|1|7e-71|267|dsi:Dsim_GD21235|calmodulin GO:0016461//unconventional myosin complex;GO:0043231//intracellular membrane-bounded organelle GO:0032028//myosin head/neck binding;GO:0046872//metal ion binding GO:0009593//detection of chemical stimulus 31961 1606.00 1.275 1.78 0.48137999410754 Up 0.21443666622639 CG15306 CG15306, isoform B K10436|1|3e-30|133|dmo:Dmoj_GI16249|microtubule-associated protein, RP/EB family - - - 38847 777.00 2.265 0.915 -1.30766740176219 Down 0.413056399418835 CG16998 CG16998 K01312|1|1e-34|146|bfo:BRAFLDRAFT_88359|trypsin [EC:3.4.21.4];K01362|2|2e-34|145|dme:Dmel_CG17240| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38217 1258.00 0.73 0.815 0.15890359535106 Up 0.0773675868445384 CG12035 CG12035 - - - - 5740128 694.00 2.235 0.51 -2.13170567921182 Down 0.484612336547352 CG34199 CG34199 - - - - 19836044 654.00 0.065 0.075 0.206450877467427 Up 0.045898824461762 2768989 1132.00 3.085 4.085 0.405065588996265 Up 0.292662792233523 CG33284 CG33284 - - - - 45970 2095.95 37.35 39.465 0.0794655062104461 Up 0.197133800026417 Pk17E protein kinase-like 17E, isoform C K08286|1|0.0|897|dme:Dmel_CG7001|protein-serine/threonine kinase [EC:2.7.11.-];K04688|2|2e-37|157|phu:Phum_PHUM176660|p70 ribosomal S6 kinase [EC:2.7.11.1];K04445|3|3e-37|157|xla:100037253|mitogen-,stress activated protein kinases [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 318993 547.04 4.65 5.72 0.298784430782996 Up 0.283152819970942 CG31870 CG31870, isoform E - - - - 319020 619.46 0.39 1.32 1.7589919004962 Up 0.364053625676925 CG31909 CG31909, isoform C - - - - 33059 2444.81 1.18 1.29 0.128584206061413 Up 0.0797781006472064 run runt, isoform C K09280|1|1e-177|624|dsi:Dsim_GD17500|runt-related transcription factor, other GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0032559;GO:0003677//DNA binding GO:0010004//gastrulation involving germ band extension;GO:0007417//central nervous system development;GO:0048812//neuron projection morphogenesis;GO:0007365//periodic partitioning;GO:0003006//developmental process involved in reproduction;GO:0010551;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis 33320 1008.00 0.655 0.9 0.458430094792225 Up 0.143343019416193 CG5556 CG5556, isoform B - - GO:0003824//catalytic activity - 14462514 650.00 6.945 5.79 -0.262411345992156 Down 0.279619601109497 38598 1082.00 61.475 63.595 0.0489135118082751 Up 0.149914146083741 CG10672 CG10672 K11147|1|3e-153|541|dme:Dmel_CG10672|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 39522 7873.68 4.995 5.525 0.145489786486376 Up 0.168636903975697 Spt20 Spt20, isoform D - - - - 32239 2280.00 13.045 12.255 -0.0901264599506125 Down 0.1670519085986 CG32649 CG32649 K08869|1|0.0|1218|dme:Dmel_CG32649|aarF domain-containing kinase GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity - 39552 8068.00 2.955 2.725 -0.116901900513244 Down 0.104807819310527 ptip ptip K10728|1|3e-06|55.8|aga:AgaP_AGAP002760|topoisomerase (DNA) II binding protein 1 GO:0044464//cell part - - 32512 618.00 6.45 8.09 0.326840542119361 Up 0.347972526746797 CG12379 CG12379 - - - - 32406 8906.89 22.755 29.895 0.393720624592024 Up 0.529982829216748 rut rutabaga, isoform G K01768|1|0.0|3242|dme:Dmel_CG9533|adenylate cyclase [EC:4.6.1.1];K08041|2|6e-133|476|tgu:100226080|adenylate cyclase 1 [EC:4.6.1.1] GO:0016021//integral to membrane GO:0004016//adenylate cyclase activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007613//memory;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0030534//adult behavior;GO:0010259//multicellular organismal aging;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0007268//synaptic transmission;GO:0048588//developmental cell growth;GO:0006164//purine nucleotide biosynthetic process;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0018988;GO:0007617//mating behavior 19834912 680.00 0.575 0.345 -0.736965594166206 Down 0.151730286619997 19835256 790.00 0.945 0.725 -0.382333334206138 Down 0.133436798309338 40700 6282.48 21.28 20.605 -0.0465036872206903 Down 0.125842028794083 CG1347 Autophagy-specific gene 17, isoform C - - - - 31781 1143.00 20.605 19.68 -0.0662642429412593 Down 0.156089023907014 Sptr sepiapterin reductase K00072|1|1e-142|506|dme:Dmel_CG12117|sepiapterin reductase [EC:1.1.1.153] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0042559//pteridine-containing compound biosynthetic process 31931 1783.00 0.03 0.06 1 Up 0.0654471007792894 CG15252 CG15252, isoform C - - - - 38429 2419.00 12.675 12.28 -0.0456751865205233 Down 0.107548540483424 CG14971 CG14971 - GO:0031224//intrinsic to membrane - - 36743 4105.94 15.39 19.66 0.35327009001237 Up 0.470017170783252 tun tungus, isoform D - - GO:0003824//catalytic activity GO:0008306//associative learning 261329 4578.01 27.04 30.22 0.160408508882645 Up 0.316503764364021 CG8176 CG8176, isoform G K12804|1|4e-06|54.7|dre:571331|proline-serine-threonine phosphatase interacting protein 1 GO:0030119//AP-type membrane coat adaptor complex;GO:0030119//AP-type membrane coat adaptor complex;GO:0030119//AP-type membrane coat adaptor complex;GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0015031//protein transport;GO:0015031//protein transport;GO:0015031//protein transport;GO:0015031//protein transport 7354420 627.26 40.935 38.955 -0.0715263805957333 Down 0.181217804781403 CG42376 CG42376, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity - 39492 2232.00 0.07 0.08 0.192645077942396 Up 0.045898824461762 snky sneaky - GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding - 40771 1232.00 0.35 0.825 1.23703919730085 Up 0.24907541936336 Osi15 osiris 15 - - - - 59172 3918.87 31.04 27.32 -0.184171073897037 Down 0.344670453044512 Capr caprin, isoform B - - GO:0016787//hydrolase activity - 32161 2344.00 0.66 1.15 0.801095931585922 Up 0.232432967903844 CG18130 CG18130 - - - GO:0019725//cellular homeostasis 19834985 952.00 10.195 13.635 0.419452924898667 Up 0.469753004887069 41996 929.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 CG10405 CG10405 K01312|1|7e-42|170|dme:Dmel_CG9564|trypsin [EC:3.4.21.4] - - - 318735 836.00 0.095 0.055 -0.788495894806288 Down 0.0694426099590543 CG31437 CG31437 - - - - 41897 3832.00 0.04 0.11 1.4594316186373 Up 0.0933166028265751 CG18516 CG18516 K00106|1|1e-136|488|phu:Phum_PHUM299090|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] - - - 32525 902.00 1.295 1.305 0.0110977088833309 Up 0.041044776119403 CG8952 CG8952 K01310|1|3e-36|152|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K09634|5|1e-28|126|mdo:100023782|transmembrane protease, serine 3 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42269 6108.20 135.005 145.33 0.106319705129484 Up 0.277374190991943 CG42613 CG42613, isoform H K13047|1|2e-32|142|rno:365460|tolloid-like protein 2 [EC:3.4.24.-];K05502|3|8e-32|140|dre:572452|bone morphogenetic protein 1 [EC:3.4.24.19] - - - 42519 708.00 17.61 19.025 0.111501544559699 Up 0.217606656980584 CG3337 CG3337 - - GO:0016741 - 2768980 9524.00 0.135 0.08 -0.754887502163469 Down 0.0813630960243033 Muc68Ca mucin 68Ca - - - - 43627 1599.25 0.565 1.625 1.52411694550063 Up 0.378351604807819 CG15539 CG15539, isoform C K00472|1|0.0|806|dme:Dmel_CG15539|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process;GO:0008152//metabolic process 3885627 876.00 1.235 0.615 -1.00585272624544 Down 0.276746796988509 CG34010 CG34010 - - GO:0016407//acetyltransferase activity - 41779 1823.00 3.35 3.27 -0.0348704598470523 Down 0.0585787874785365 Rad17 Rad17 K06662|1|0.0|960|dme:Dmel_CG7825|cell cycle checkpoint protein - - - 49077 641.00 23.18 19.925 -0.218300842128638 Down 0.368841632545238 CSN8 COP9 complex homolog subunit 8 K12181|1|8e-73|272|dme:Dmel_CG42522|COP9 signalosome complex subunit 8 GO:0008287//protein serine/threonine phosphatase complex GO:0004721//phosphoprotein phosphatase activity GO:0000278//mitotic cell cycle;GO:0006952//defense response;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0007292//female gamete generation;GO:0048592//eye morphogenesis;GO:0031647//regulation of protein stability;GO:0007051//spindle organization;GO:0006464//cellular protein modification process 3355089 1353.23 227.93 245.52 0.107249727222984 Up 0.281898031964073 mRpS5 mitochondrial ribosomal protein S5, isoform D - GO:0000314//organellar small ribosomal subunit;GO:0000314//organellar small ribosomal subunit;GO:0000314//organellar small ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity - 40797 4690.94 6 6.69 0.15704371014558 Up 0.194128912957337 CG15186 CG15186, isoform M - - - - 64874 1841.00 11.345 9.86 -0.202397057294426 Down 0.284704794611016 ligatin ligatin K07575|1|8e-11|68.9|tca:658422|PUA domain protein - GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 34593 2426.00 26.515 25.5 -0.0563115013945257 Down 0.150475498613129 CycY cyclin Y, isoform B - - - - 42195 494.00 15.035 17.865 0.248811046011267 Up 0.376304319112403 CG14312 CG14312 - - - - 3355079 747.87 127.33 131.735 0.0490663286469886 Up 0.155923920221899 CG40045 CG40045, isoform D K10575|1|5e-86|317|dvi:Dvir_GJ11187|ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process 33639 1961.00 3.53 3.005 -0.232303192559995 Down 0.186104873860785 CG17612 CG17612, isoform B K09228|1|2e-40|167|mmu:380850|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 37732 3207.00 0.08 0.21 1.39231742277876 Up 0.12534671773874 alphaPS5 integrin alphaPS5 subunit K06487|1|1e-61|238|dre:100151255|integrin alpha V;K06584|2|7e-58|226|mdo:100027090|integrin alpha 8 GO:0005924//cell-substrate adherens junction;GO:0005887//integral to plasma membrane GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity GO:0048565//digestive tract development;GO:0016337//cell-cell adhesion;GO:0007613//memory;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0006935//chemotaxis;GO:0007160//cell-matrix adhesion;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0008306//associative learning;GO:0035272//exocrine system development 12798457 318.00 13.485 12 -0.168321115739723 Down 0.269515255580505 CG43392 CG43392 - - - - 14462804 784.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 37025 1998.00 10.235 4.27 -1.26120312740292 Down 0.63426231673491 CG5002 CG5002 K13962|1|2e-22|107|cfa:487043|solute carrier family 26 (sulfate anion transporter), member 7 - - - 32845 911.00 0.19 0.105 -0.855610090664825 Down 0.0938779553559635 CG15047 CG15047 - - - - 32916 1468.00 3.41 3.31 -0.0429405222169547 Down 0.0640272090873068 CG7889 CG7889 - - - - 37905 3725.00 5.725 7.18 0.326708150838745 Up 0.332683925505217 CG13579 CG13579, isoform B K05051|1|4e-13|77.0|rno:113914|trace amine associated receptor;K04280|2|2e-12|74.7|aga:AgaP_AGAP002156|gonadotropin-releasing hormone receptor;K04153|3|2e-12|74.7|mdo:100032349|5-hydroxytryptamine (serotonin) receptor 1A - - - 39750 3766.94 20.87 20.335 -0.0374656096977018 Down 0.109463743230749 mib1 mind bomb 1, isoform B K10645|1|0.0|2024|dme:Dmel_CG5841|E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19] GO:0044448//cell cortex part GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation;GO:0008593//regulation of Notch signaling pathway;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0033036;GO:0030100//regulation of endocytosis 5740709 244.00 0.215 0.735 1.77340759013427 Up 0.275789195614846 CG41518 CG41518 - - - - 32258 1063.73 16.585 17.04 0.0390463234378159 Up 0.105204068154801 CG2200 CG2200, isoform B K05995|1|2e-127|455|dme:Dmel_CG2200|dipeptidase E [EC:3.4.13.21] GO:0044424//intracellular part GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 32053 489.00 408.795 623.115 0.608120896066332 Up 0.679896975300489 CG15201 CG15201 - - - - 38817 2892.00 10.135 15.035 0.568978779107104 Up 0.544842160877031 CTCF CTCF K09228|1|9e-61|235|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0031490//chromatin DNA binding GO:0006350;GO:0007389//pattern specification process 37793 1875.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 CG17658 CG17658 - - GO:0046914//transition metal ion binding - 246445 4605.00 2.265 2.25 -0.00958604882919808 Down 0.0432901862369568 Rif1 Rap1 interacting factor 1 homolog K11138|1|2e-15|85.5|dre:567001|telomere-associated protein RIF1 - - - 36515 2074.00 0.885 1.19 0.427212213224946 Up 0.160744947827236 S-Lap5 Sperm-Leucylaminopeptidase 5 K01255|1|0.0|813|dpo:Dpse_GA14907|leucyl aminopeptidase [EC:3.4.11.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 40545 2625.22 23.525 24.3 0.0467615908772443 Up 0.130035662395985 CG9795 CG9795, isoform F - - - - 32263 2499.48 15.595 12.62 -0.305371642391603 Down 0.415995245013869 MFS10 major facilitator superfamily transporter 10, isoform C K12301|1|2e-110|399|nve:NEMVE_v1g228652|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5;K08193|4|2e-105|383|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport 36845 2375.00 0.95 1.645 0.792088165404294 Up 0.279289393739268 CG7813 CG7813 K02138|1|6e-22|106|aga:AgaP_AGAP011131|F-type H+-transporting ATPase subunit d [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex - GO:0006754//ATP biosynthetic process 35095 2422.00 1.085 2.69 1.30991113011214 Up 0.442345793158103 CG5790 CG5790, isoform B K02214|1|0.0|1209|dme:Dmel_CG5790|cell division control protein 7 [EC:2.7.11.1] - GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0065008;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process 32761 1947.67 48.98 35.28 -0.473342213006458 Down 0.595396909259015 CG6398 CG6398, isoform B - - - GO:0021782//glial cell development 246653 5172.90 23.065 20.275 -0.186003377961021 Down 0.335886936996434 CG30497 CG30497, isoform D - - - - 33264 1256.90 7.99 7.73 -0.0477270890031294 Down 0.0921278562937525 CG4291 CG4291, isoform B K13220|1|2e-152|538|dme:Dmel_CG4291|WW domain-binding protein 4 GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding GO:0000377 33609 3437.00 1.595 2.6 0.704955199263585 Up 0.323107911768591 CG3964 CG3964, isoform C K05755|1|1e-23|112|ecb:100058358|actin related protein 2/3 complex, subunit 4;K06047|2|4e-20|100|ssc:445530|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 42510 1516.34 20.935 17.835 -0.23120570227349 Down 0.372341830669661 CG5802 medial glomeruli, isoform B - GO:0042598;GO:0031224//intrinsic to membrane;GO:0042598;GO:0031224//intrinsic to membrane GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity GO:0006810//transport;GO:0006810//transport 43735 831.00 10.355 9.555 -0.115999775243055 Down 0.18709549597147 CG11563 CG11563 - - - - 318224 2899.61 25.07 29.655 0.242313375616425 Up 0.407244749702813 CG32815 CG32815, isoform D - - - - 36501 2129.00 71.455 82.585 0.20884480107436 Up 0.419099194294017 CG13330 CG13330 - - - - 5740825 300.00 8.94 26.865 1.5873811015238 Up 0.729560163782856 CG34305 CG34305 - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19834755 406.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 34058 1634.83 6.735 8.085 0.263569828011359 Up 0.298144234579316 CG7191 CG7191, isoform B - - - - 40070 1309.00 18.2 24.115 0.405992359675837 Up 0.521595562012944 CG6836 CG6836 - - - - 40189 762.59 156.56 154.69 -0.0173357249026681 Down 0.0909391097609299 Tom20 translocase of outer membrane 20, isoform B - GO:0005741//mitochondrial outer membrane GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting 40440 920.00 0.2 0.255 0.350497247084133 Up 0.0768062343151499 CG7448 CG7448, isoform C K08211|1|1e-16|87.8|hsa:55356|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 15 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 32856 997.00 0.915 1.38 0.592824618494126 Up 0.211431779157311 CG6696 CG6696 K08076|1|2e-43|176|cel:F09E8.6|astacin [EC:3.4.24.21];K08606|4|5e-38|158|dre:100151009|meprin A, beta [EC:3.4.24.18] GO:0016021//integral to membrane GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39849 862.00 16.585 14.955 -0.14925110166867 Down 0.26251485933166 tra transformer, isoform B - GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus - GO:0002118//aggressive behavior;GO:0008049//male courtship behavior;GO:0000398//mRNA splicing, via spliceosome;GO:0007275//multicellular organismal development;GO:0003006//developmental process involved in reproduction;GO:0006412//translation;GO:0007548//sex differentiation;GO:0002118//aggressive behavior;GO:0008049//male courtship behavior;GO:0000398//mRNA splicing, via spliceosome;GO:0007275//multicellular organismal development 41965 669.00 12.97 18.565 0.517406835603041 Up 0.54877162858275 Bin1 bicoid interacting protein 1 - - - - 12798023 724.00 0.315 0.01 -4.97727992349992 Down 0.276482631092326 33475 1930.00 0.55 1.13 1.03881924889053 Up 0.268095363888522 CG2964 CG2964 K00873|1|0.0|1057|dme:Dmel_CG2964|pyruvate kinase [EC:2.7.1.40] - GO:0031420;GO:0016301//kinase activity GO:0006007//glucose catabolic process 40462 3777.00 11.42 11.84 0.0521064302661069 Up 0.110025095760137 Hem HEM-protein K05750|1|0.0|2168|dme:Dmel_CG5837|NCK-associated protein 1 GO:0044424//intracellular part;GO:0016020//membrane GO:0005488//binding;GO:0016491//oxidoreductase activity GO:0065008;GO:0048741//skeletal muscle fiber development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006909//phagocytosis;GO:0030030//cell projection organization;GO:0000768//syncytium formation by plasma membrane fusion;GO:0009887//organ morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0003006//developmental process involved in reproduction 49968 5376.39 124.17 148.555 0.258680509194817 Up 0.484975564654603 Caps calcium activated protein for secretion, isoform F - - - - 42941 2270.00 0.195 0.05 -1.96347412397489 Down 0.139050323603223 CG13627 CG13627, isoform C - - - - 5740784 397.14 2.86 9.68 1.7589919004962 Up 0.671872936203936 CG11741 CG11741, isoform B - - - - 38869 3209.00 23.51 26.72 0.184645468821031 Up 0.336019019944525 CG13685 CG13685, isoform C - - - - 40124 4569.21 27.225 32.02 0.234041258911988 Up 0.40268788799366 CG9279 CG9279, isoform C K04648|1|5e-169|596|aga:AgaP_AGAP004194|dynactin 1 - - GO:0007017//microtubule-based process 42192 2915.00 7.83 5.285 -0.567108835908358 Down 0.458129705455026 CG7146 vacuolar protein sorting 39 - - - - 32093 2581.24 31.85 31.025 -0.0378621621259439 Down 0.119237881389513 Cyp4g15 Cyp4g15, isoform C K00517|1|2e-102|373|dme:Dmel_CG3972| [EC:1.14.-.-];K07427|4|1e-53|210|spu:579739|cytochrome P450, family 4, subfamily V GO:0044464//cell part;GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008202//steroid metabolic process;GO:0008202//steroid metabolic process 36994 1590.00 3.585 2.535 -0.499987371698564 Down 0.311088363492273 CG6484 CG6484 K08145|1|1e-73|277|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 - - - 50105 1501.68 21.11 17.735 -0.251327248411967 Down 0.391758024039097 CG32428 CG32428, isoform C - - - - 2768886 1820.00 3.1 6.795 1.13220533549315 Up 0.56765949015982 Sdic4 Sperm-specific dynein intermediate chain 4 - - - - 31844 4267.00 6.175 7.145 0.210494874623776 Up 0.242537313432836 CG7065 CG7065 - - - - 44790 1607.00 14.14 21.74 0.62056982021791 Up 0.594934618940695 TwdlT TweedleT - - - - 32099 753.65 18.155 18.065 -0.00716967536776374 Down 0.053625676925109 PGRP-SA peptidoglycan recognition protein SA, isoform B K01446|1|9e-110|396|dme:Dmel_CG11709|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0008329//pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0042834//peptidoglycan binding GO:0002815;GO:0000270//peptidoglycan metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0008063//Toll signaling pathway 36051 1251.00 10.35 11.625 0.167599948496069 Up 0.256273940034342 cdc2rk cdc2-related-kinase K02449|1|0.0|647|dpo:Dpse_GA12412|cyclin-dependent kinase 10 [EC:2.7.11.22] GO:0005681//spliceosomal complex GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0000377;GO:0006464//cellular protein modification process 39514 1097.00 6.145 5.715 -0.104659512158183 Down 0.135583146215824 CG10133 CG10133 K01047|1|0.0|655|dme:Dmel_CG10133|phospholipase A2 [EC:3.1.1.4] - - - 35538 1877.00 2.715 1.72 -0.658543633102263 Down 0.316239598467838 CG14590 CG14590 K11848|1|4e-25|116|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15];K11426|2|4e-11|70.1|cel:T22A3.4|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006350 40059 1585.00 224.63 193.435 -0.215701758076807 Down 0.447728173292828 CG3902 CG3902 K09478|1|0.0|791|dme:Dmel_CG3902|short/branched chain acyl-CoA dehydrogenase [EC:1.3.99.12] - GO:0030554//adenyl nucleotide binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0008152//metabolic process 19836142 665.00 0.185 0.345 0.899071091149219 Up 0.130828160084533 32696 673.00 2.195 16.595 2.91845578454294 Up 0.764661207238146 Arpc3B Actin-related protein 2/3 complex, subunit 3B, isoform C K05756|1|3e-98|357|dsi:Dsim_GD15703|actin related protein 2/3 complex, subunit 3 GO:0015629//actin cytoskeleton;GO:0045171//intercellular bridge;GO:0015629//actin cytoskeleton;GO:0045171//intercellular bridge GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0008064//regulation of actin polymerization or depolymerization;GO:0008064//regulation of actin polymerization or depolymerization 43805 2894.72 115.405 84.26 -0.453785910067106 Down 0.613657376832651 CG1732 CG1732, isoform B K05034|1|0.0|952|dme:Dmel_CG1732|solute carrier family 6 (neurotransmitter transporter, GABA) member 1 - - - 34573 7148.04 11.915 10.865 -0.133090777008988 Down 0.214700832122573 CG6509 CG6509, isoform D K12076|1|2e-36|156|gga:424890|disks large protein 1;K11828|3|1e-35|153|dre:100000823|discs large protein 4;K12075|5|3e-35|152|dre:497638|discs large protein - GO:0005488//binding;GO:0005488//binding GO:0006959//humoral immune response;GO:0006959//humoral immune response 43796 8895.09 29.04 30.07 0.0502834145782523 Up 0.137267203803989 Thd1 Thd1, isoform C K03649|1|0.0|3068|dme:Dmel_CG1981|TDG/mug DNA glycosylase family protein [EC:3.2.2.-] - - - 2768945 3731.00 6.735 7.73 0.198790468462545 Up 0.243263769647339 CG42458 CG42458 K12884|1|2e-25|118|xla:397793|heterogeneous nuclear ribonucleoprotein C1/C2;K12895|5|3e-24|114|dre:402903|heterogeneous nuclear ribonucleoprotein C-like 2 GO:0044464//cell part GO:0046914//transition metal ion binding - 36645 1211.26 26.24 24.625 -0.0916439953869829 Down 0.201426495839387 BEAF-32 boundary element-associated factor of 32kD, isoform C - GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0031490//chromatin DNA binding;GO:0031490//chromatin DNA binding GO:0051276//chromosome organization;GO:0007292//female gamete generation;GO:0051276//chromosome organization;GO:0007292//female gamete generation 32455 3220.48 4.79 5.1 0.0904715911226776 Up 0.113129045040285 CG5877 CG5877, isoform D - GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - - 31014 809.40 130.495 114.29 -0.191295352072088 Down 0.404570070003963 Roc1a Roc1a, isoform D K03868|1|2e-63|243|dsi:Dsim_GD16520|RING-box protein 1 - - - 37737 1056.64 2.77 2.87 0.0511647606264999 Up 0.0653810593052437 CG17664 CG17664, isoform C K09884|1|1e-152|538|dme:Dmel_CG17664|aquaporin rerated protein, invertebrate GO:0031224//intrinsic to membrane GO:0022803 GO:0003008;GO:0006810//transport 34461 3392.00 11.495 18.675 0.700101776958419 Up 0.602562409192973 CG17097 CG17097 K01046|1|1e-70|268|dpo:Dpse_GA20265|triacylglycerol lipase [EC:3.1.1.3];K01066|3|3e-67|257|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 40778 706.00 1.025 0.69 -0.570955642727277 Down 0.178840311715757 CG17917 CG17917 - - - - 49165 2787.00 2.355 2.57 0.126041299581095 Up 0.103652093514727 Cyp303a1 Cyp303a1, isoform B K00517|1|0.0|1034|dme:Dmel_CG4163| [EC:1.14.-.-];K07412|3|7e-58|225|ssc:403104|cytochrome P450, family 2, subfamily B [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0048513//organ development;GO:0008152//metabolic process 246630 1800.00 0.025 0.05 1 Up 0.0577202483159424 Ir52c ionotropic receptor 52c - - - - 36287 1027.70 62.065 57.785 -0.103084883765645 Down 0.245872407872144 CG8321 CG8321, isoform B - - - - 42261 1365.00 154.79 246.24 0.66975286566088 Up 0.685840707964602 Rh2 rhodopsin 2 K13802|1|4e-152|537|dvi:Dvir_GJ10183|opsin Rh1 GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction 40172 2132.16 15.555 16.82 0.112799310720762 Up 0.212125214634791 Prp3 precursor RNA processing 3, isoform B K12843|1|0.0|1045|dme:Dmel_CG7757|U4/U6 small nuclear ribonucleoprotein PRP3 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex - GO:0000377;GO:0000377 38779 1970.00 7.35 9.25 0.331709115679948 Up 0.368478404437987 msl-3 male-specific lethal 3 K11339|1|4e-10|66.6|spu:585759|mortality factor 4-like protein 1 GO:0000805//X chromosome;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0006325//chromatin organization;GO:0007549//dosage compensation 38792 1257.00 0.035 0.04 0.192645077942396 Up 0.0382380134724607 CG14829 CG14829 - - - - 326166 1335.00 11.175 11.5 0.0413590297610575 Up 0.0951327433628319 Tap42 Two A-associated protein of 42kDa - - - GO:0050896//response to stimulus;GO:0007165//signal transduction 35132 3640.29 10.51 5.475 -0.940831799473643 Down 0.593415665037644 CG10348 CG10348, isoform C K04462|1|2e-49|197|oaa:100084365|ecotropic virus integration site 1 protein GO:0044464//cell part GO:0046914//transition metal ion binding - 39889 2598.15 146.57 126.405 -0.213536311331764 Down 0.431151763307357 Lmpt limpet, isoform N K05760|1|2e-34|148|dmo:Dmoj_GI17221|paxillin GO:0031672//A band;GO:0031672//A band;GO:0031672//A band;GO:0031672//A band GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding - 37789 920.00 79.27 87.59 0.143991192816086 Up 0.323537181349888 CG5597 CG5597 - - - - 38590 5029.15 33.37 37.38 0.163714882562839 Up 0.326971338000264 Con connectin, isoform B K06260|1|1e-16|89.7|mmu:14729|platelet glycoprotein V GO:0016020//membrane GO:0005488//binding GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0008039//synaptic target recognition 14462507 2692.27 0.45 0.365 -0.302028537449657 Down 0.0869105798441421 19836003 3221.00 2.885 3.655 0.341300087306955 Up 0.25069343547748 - CG45069, isoform B - - - - 12798119 704.00 0.23 0.255 0.148863385914483 Up 0.0503566239598468 CG43136 CG43136 - - - - 33913 1298.00 1.175 2.03 0.788818970620176 Up 0.30630035662396 CG9550 CG9550 K01025|1|2e-48|192|dpo:Dpse_GA16353| [EC:2.8.2.-];K04746|3|3e-10|66.6|mcc:708116|carbohydrate 6-sulfotransferase 4 [EC:2.8.2.-] - GO:0016782//transferase activity, transferring sulfur-containing groups - 12798557 303.00 0.89 0.17 -2.38827058971606 Down 0.339651301017039 CG43056 CG43056 - - - - 246414 2809.00 0.32 0.26 -0.299560281858908 Down 0.0747259278827103 CG30047 CG30047 - - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 42360 1760.04 44.175 30.625 -0.528520290661684 Down 0.612435609562805 CG4572 CG4572, isoform D K09645|1|0.0|1010|dme:Dmel_CG4572|vitellogenic carboxypeptidase-like protein [EC:3.4.16.-] - GO:0004180//carboxypeptidase activity;GO:0004180//carboxypeptidase activity;GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process;GO:0050658//RNA transport;GO:0019538//protein metabolic process;GO:0050658//RNA transport;GO:0019538//protein metabolic process;GO:0050658//RNA transport 34077 2552.00 15.005 8 -0.907371413823564 Down 0.624554220050192 spz3 spatzle 3 - - - - 37485 1729.00 37.74 33.65 -0.165487918102766 Down 0.339420155857879 lox2 lysyl oxidase-like 2 K00280|1|1e-106|387|hsa:4017| [EC:1.4.3.-] GO:0044464//cell part GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0046914//transition metal ion binding;GO:0004888//transmembrane signaling receptor activity GO:0043412//macromolecule modification;GO:0009987//cellular process 318894 1001.00 1.085 0.69 -0.65302677566631 Down 0.196572447497028 CG33136 CG33136, isoform C - - - - 41627 5051.00 8.64 8.585 -0.00921317816133434 Down 0.0492999603751156 Su(var)3-7 suppressor of variegation 3-7, isoform B - GO:0000785//chromatin;GO:0005700//polytene chromosome GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0007549//dosage compensation 3885603 223.00 165.265 178.405 0.110374827502921 Up 0.279685642583542 IM14 immune induced molecule 14 - - - GO:0006950//response to stress 36241 10383.47 15.635 17.01 0.121603921738344 Up 0.225201426495839 tou toutatis, isoform G K11655|1|7e-18|92.8|tad:TRIADDRAFT_61269|bromodomain adjacent to zinc finger domain protein 1A GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0048731;GO:0048731;GO:0048731 19835061 585.00 68.43 95.57 0.481928871215819 Up 0.620525690133404 3772104 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33888 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 2768990 5578.00 0.175 0.17 -0.0418201756946271 Down 0.0418702945449742 Muc68E mucin 68E K01873|1|3e-16|89.0|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K10955|5|3e-16|88.6|hsa:4583|intestinal mucin-2 - - - 3885611 466.00 13.35 18.525 0.47263380061828 Up 0.528926165632017 nimB3 nimrod B3 - - - - 3772474 164.00 1.03 1 -0.0426443374084937 Down 0.0480451723682473 33462 1560.43 340.015 336.125 -0.0166005431714906 Down 0.0925571258750495 CG9894 bacchus, isoform D - - - - 3772572 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 33258 1370.00 14.455 14.895 0.0432595147724807 Up 0.104543653414344 CG3876 CG3876 - GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0022892 GO:0006497//protein lipidation 38768 926.00 0.63 0.985 0.64477189595646 Up 0.187987055871087 CG17744 CG17744 - - - - 44831 2632.00 16.615 16.135 -0.0422927152050898 Down 0.106855105005944 L lobe - - - GO:0007444//imaginal disc development;GO:0043409//negative regulation of MAPK cascade;GO:0016055//Wnt receptor signaling pathway;GO:0001654//eye development;GO:0012501//programmed cell death 35513 2155.05 11.305 11.5 0.0246728690802086 Up 0.0696077136441685 CG11163 zinc transporter 41F, isoform D K03295|1|3e-26|120|xtr:100124729|cation efflux system protein, CDF family GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport 38136 692.00 1.25 5.71 2.19156265070076 Up 0.637564390437195 Psf1 Psf1 K10732|1|1e-114|412|dme:Dmel_CG9187|GINS complex subunit 1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0003678//DNA helicase activity GO:0006259//DNA metabolic process 33644 4836.05 11.39 11.29 -0.0127222609351112 Down 0.0547483819838859 l(2)k05819 lethal (2) k05819, isoform D - GO:0044464//cell part;GO:0044464//cell part GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0042625//ATPase activity, coupled to transmembrane movement of ions GO:0009206;GO:0006811//ion transport;GO:0009206;GO:0006811//ion transport 35013 3251.00 0.9 0.86 -0.0655883416275767 Down 0.0525359926033549 CG13272 CG13272, isoform B - - - - 38209 922.00 8.34 7.165 -0.219080679182518 Down 0.268326509047682 RabX5 RabX5 K07976|1|6e-140|496|dme:Dmel_CG7980|Rab family, other;K07922|3|5e-46|184|dre:780839|Ras-related protein Rab-36;K07921|4|1e-44|179|dre:450074|Ras-related protein Rab-34 GO:0030529//ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0035556//intracellular signal transduction;GO:0010467//gene expression 39252 3289.00 28.815 30.215 0.0684449223129882 Up 0.171773873992868 fd68A forkhead domain 68A, isoform P K09404|1|3e-60|234|nvi:100123931|forkhead box protein K - GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding - 41134 12272.14 10.62 13.225 0.316483956197234 Up 0.405560692114648 CG16779 CG16779, isoform E K09228|1|2e-15|86.3|mmu:22698|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 42834 4674.26 15.055 13.06 -0.205087811178247 Down 0.319772817329283 Aats-glupro Glutamyl-prolyl-tRNA synthetase, isoform B K01881|1|0.0|1587|dme:Dmel_CG5394|prolyl-tRNA synthetase [EC:6.1.1.15];K01885|1|0.0|1587|dme:Dmel_CG5394|glutamyl-tRNA synthetase [EC:6.1.1.17] GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 32457 5169.27 18.125 19.14 0.0786098346963665 Up 0.171212521463479 gce germ cell-expressed bHLH-PAS, isoform G K09099|1|1e-18|96.3|dre:58099|aryl hydrocarbon receptor nuclear translocator-like protein 2;K02296|2|3e-18|94.7|bta:530705|aryl hydrocarbon receptor nuclear translocator-like protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0060089;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0023060;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0023060 12798058 329.00 0.14 4.565 5.02711612792662 Up 0.735041606128649 CG43061 CG43061 - - - - 38520 1075.32 25.715 30.74 0.257507011338314 Up 0.429071456874917 CG11586 CG11586, isoform B K12848|1|4e-70|265|dya:Dyak_GE20629|U4/U6.U5 tri-snRNP component SNU23 GO:0044464//cell part GO:0046914//transition metal ion binding - 19836187 765.00 0.055 0.12 1.12553088208386 Up 0.0856557918372738 50405 391.67 183.385 191.065 0.0591878859248215 Up 0.17979791308942 CG9034 CG9034, isoform B - - - - 36794 2147.00 4.965 6.21 0.322799550692108 Up 0.310196803592656 calypso calypso, isoform B K08588|1|0.0|825|dme:Dmel_CG8445|ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12] GO:0031519//PcG protein complex;GO:0000785//chromatin;GO:0031519//PcG protein complex;GO:0000785//chromatin GO:0005488//binding;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0005488//binding;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity GO:0016458//gene silencing;GO:0019941//modification-dependent protein catabolic process;GO:0035521;GO:0016458//gene silencing;GO:0019941//modification-dependent protein catabolic process;GO:0035521 40176 682.37 62.84 54.66 -0.20119772077099 Down 0.399253731343284 CG7770 CG7770, isoform B K04798|1|3e-58|224|dme:Dmel_CG7770|prefoldin beta subunit GO:0043234//protein complex GO:0005515//protein binding GO:0044267//cellular protein metabolic process 46246 1085.00 2.34 3.8 0.699490888747544 Up 0.383667943468498 Pglym87 Pglym87 K01834|1|0.0|586|dsi:Dsim_GD20588|phosphoglycerate mutase [EC:5.4.2.1] - GO:0004619//phosphoglycerate mutase activity GO:0006007//glucose catabolic process 49953 3141.46 115.95 124.12 0.0982327819953532 Up 0.255514463082816 CG14476 CG14476, isoform E K05546|1|0.0|1917|dme:Dmel_CG14476|alpha 1,3-glucosidase [EC:3.2.1.84] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0015926//glucosidase activity;GO:0005488//binding;GO:0015926//glucosidase activity;GO:0005488//binding;GO:0015926//glucosidase activity;GO:0005488//binding;GO:0015926//glucosidase activity;GO:0005488//binding;GO:0015926//glucosidase activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 19835727 3560.80 77.015 94.385 0.293418136650254 Up 0.50706643772289 - CG44247, isoform B K04450|1|7e-09|63.5|dre:100006516|activating transcription factor 2 GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0000165//MAPK cascade;GO:0006970//response to osmotic stress;GO:0019432//triglyceride biosynthetic process;GO:0002251;GO:0007610//behavior;GO:0010551;GO:0000165//MAPK cascade;GO:0006970//response to osmotic stress;GO:0019432//triglyceride biosynthetic process;GO:0002251;GO:0007610//behavior;GO:0010551 5740177 1005.00 110.87 146.325 0.400307235137095 Up 0.592425042926958 31081 2230.65 5.975 5.5 -0.119507094456089 Down 0.149749042398626 CG11418 CG11418, isoform C K13291|1|1e-06|54.7|tgu:100221843|terminal uridylyltransferase [EC:2.7.7.52] - - - 318575 1266.00 0.095 0.18 0.921997487998727 Up 0.0946374323074891 CG31065 pickpocket 31 - GO:0016020//membrane GO:0004175//endopeptidase activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0005261//cation channel activity;GO:0032559 GO:0044260;GO:0019538//protein metabolic process;GO:0030001//metal ion transport 33928 7430.53 23.17 21.43 -0.112626194188274 Down 0.229758288204993 CG31635 CG31635, isoform H K12653|1|1e-07|60.8|cfa:489370|NLR family member X1;K08727|5|3e-06|55.8|mcc:695655|nucleotide-binding oligomerization domain-containing protein 1 - - - 19835070 468.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 34633 2586.00 10.205 9.15 -0.157432533861314 Down 0.231310262845067 Ced-12 Ced-12 K12366|1|0.0|1426|dme:Dmel_CG5336|engulfment and cell motility protein 1 GO:0015630//microtubule cytoskeleton - GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0006897//endocytosis 33886 1722.00 0.135 0.105 -0.362570079384708 Down 0.0611874257033417 ppk7 pickpocket 7 K04831|1|4e-14|79.7|mmu:241118|amiloride-sensitive cation channel 4, pituitary;K04829|4|3e-13|77.0|dre:407670|amiloride-sensitive cation channel 2, neuronal GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 31060 1216.47 63.385 49.45 -0.358170947361299 Down 0.549729229956413 CG11378 CG11378, isoform C - - - - 37990 1295.33 2.01 1.87 -0.104157231291292 Down 0.0813300752872804 CG15861 CG15861, isoform B K01691|1|3e-11|69.3|dre:30476|WNT inhibitory factor 1 - - - 43570 1260.00 6.735 7.345 0.125084545093977 Up 0.172632413155462 Sry-beta serendipity beta K09228|1|5e-25|115|ptr:468662|KRAB domain-containing zinc finger protein GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 38619 3735.00 0.17 0.015 -3.50250034052918 Down 0.170155857878748 CG4835 CG4835 K01873|1|6e-19|97.1|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - - - 32558 854.74 15.665 19.33 0.303296867840182 Up 0.432142385418043 Rrp47 Rrp47, isoform B - - - - 41725 860.00 1.68 1.975 0.233391420285705 Up 0.135946374323075 CG3199 CG3199 - - - - 33770 2685.33 2.76 2.24 -0.301169534720565 Down 0.199313168669925 mid midline, isoform B K10185|1|4e-85|316|tgu:100225521|T-box protein 20 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007447//imaginal disc pattern formation;GO:0045595//regulation of cell differentiation;GO:0001709//cell fate determination;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:2000026//regulation of multicellular organismal development;GO:0010468//regulation of gene expression;GO:0014016//neuroblast differentiation;GO:0006935//chemotaxis;GO:0010002//cardioblast differentiation;GO:0006351//transcription, DNA-dependent;GO:0001708//cell fate specification;GO:0009790//embryo development 33035 15917.00 8.52 11.35 0.413766961952439 Up 0.441949544313829 HERC2 HECT and RLD domain containing protein 2 ortholog K10595|1|0.0|8514|dme:Dmel_CG11734|E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19] GO:0000152//nuclear ubiquitin ligase complex GO:0019787//small conjugating protein ligase activity;GO:0005506//iron ion binding GO:0032446//protein modification by small protein conjugation;GO:0007088//regulation of mitosis 50003 6335.90 18.36 22.94 0.321299332602017 Up 0.462554484216088 CG43462 CG45263, isoform E K06255|1|2e-17|92.0|cfa:403440|heparan sulfate proteoglycan 2 (perlecan) GO:0044464//cell part - - 317996 1046.00 0.83 1.425 0.779778677705179 Up 0.257330603619073 CG32364 CG32364 - - GO:0005488//binding - 3772015 2077.26 0.25 0.33 0.400537929583729 Up 0.0869105798441421 CG43164 CG43164, isoform E - - GO:0030246//carbohydrate binding;GO:0030246//carbohydrate binding;GO:0030246//carbohydrate binding - 19836149 400.00 0.215 0.01 -4.4262647547021 Down 0.216153744551578 43356 2346.00 6.63 6.19 -0.0990694608983232 Down 0.13716814159292 CG5527 CG5527 K01389|1|0.0|737|dme:Dmel_CG8358|neprilysin [EC:3.4.24.11];K08635|2|4e-70|266|cqu:CpipJ_CPIJ002051|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40567 2705.87 111.15 86.215 -0.366497146757334 Down 0.57135781270638 CG31522 CG31522, isoform I K03254|1|3e-136|367|dse:Dsec_GM10701|translation initiation factor eIF-3 subunit 10;K10250|3|5e-78|293|dre:327274|elongation of very long chain fatty acids protein 7 GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006413//translational initiation;GO:0006631//fatty acid metabolic process;GO:0006413//translational initiation;GO:0006631//fatty acid metabolic process;GO:0006413//translational initiation;GO:0006631//fatty acid metabolic process 35991 1814.00 10.21 11.89 0.219765848867854 Up 0.307257957997623 Map60 Microtubule-associated protein 60 - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0015631//tubulin binding GO:0009987//cellular process 44355 3104.00 12.575 13.31 0.0819521712190023 Up 0.155296526218465 drl derailed, isoform B K05128|1|0.0|1157|dme:Dmel_CG17348|RYK receptor-like tyrosine kinase [EC:2.7.10.1] GO:0016021//integral to membrane GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0032559 GO:0023060;GO:0035216;GO:0016198//axon choice point recognition;GO:0007431//salivary gland development;GO:0007166//cell surface receptor signaling pathway;GO:0008306//associative learning;GO:0006464//cellular protein modification process 19835749 2017.00 39.29 41.79 0.0889955908637223 Up 0.216913221503104 - CG44245, isoform B - - - - 39463 4206.00 0.425 0.29 -0.55140994101013 Down 0.112798837670057 CG14120 CG14120 - - GO:0043169//cation binding;GO:0003824//catalytic activity - 14462710 546.00 0.85 0.53 -0.681470481574503 Down 0.177420420023775 35170 3941.79 21.33 22.31 0.0648065479035692 Up 0.149088627658169 mib2 mind bomb 2, isoform C K10645|1|0.0|1910|dme:Dmel_CG17492|E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19] GO:0043234//protein complex;GO:0031672//A band;GO:0031982//vesicle;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0032036//myosin heavy chain binding;GO:0032027//myosin light chain binding;GO:0019787//small conjugating protein ligase activity GO:0050931//pigment cell differentiation;GO:0000768//syncytium formation by plasma membrane fusion;GO:0019725//cellular homeostasis;GO:0016567//protein ubiquitination 34902 948.00 0.125 0.14 0.16349873228288 Up 0.0504556861709153 nht no hitter K03129|1|1e-10|67.4|dya:Dyak_GE19522|transcription initiation factor TFIID subunit D3 GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0048232//male gamete generation 40281 1927.43 39.155 50.09 0.355326063604069 Up 0.539393739268261 CG4825 CG4825, isoform B K08729|1|0.0|944|dme:Dmel_CG4825|phosphatidylserine synthase 1 [EC:2.7.8.-] - - GO:0006658//phosphatidylserine metabolic process 317987 2844.00 12.285 13.49 0.134992490586103 Up 0.226225069343548 CG32350 CG32350 - - GO:0046914//transition metal ion binding - 31033 881.00 0.4 0.2 -1 Down 0.151334037775723 CG11664 CG11664 K01312|1|1e-17|90.1|dme:Dmel_CG18211|trypsin [EC:3.4.21.4] - - - 42058 4285.00 9.495 8.765 -0.11541390938996 Down 0.18072249372606 Patr-1 protein associated with topo II related - 1, isoform B K12617|1|0.0|1380|dme:Dmel_CG5208|DNA topoisomerase 2-associated protein PAT1 - - - 31508 1433.00 0.11 0.095 -0.211504105193712 Down 0.0516774534407608 CG15767 CG15767 K09564|1|9e-07|55.1|smm:Smp_094810|peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8];K03767|2|3e-06|53.1|ptr:473924|peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8];K09565|3|6e-06|52.4|aag:AaeL_AAEL011758|peptidyl-prolyl isomerase F (cyclophilin F) [EC:5.2.1.8] - - - 38971 3397.81 12.495 14.045 0.168705723039695 Up 0.27258618412363 CG6765 CG6765, isoform C K09237|1|2e-09|65.5|nvi:100122117|Cys2His2 zinc finger developmental/cell cycle regulator, other - GO:0046914//transition metal ion binding - 36449 623.00 0.985 0.88 -0.162620200819079 Down 0.0800752872804121 CG33137 CG33137 - - - - 37414 2797.00 3.53 3.74 0.0833700866164565 Up 0.0920618148197068 Xpd xeroderma pigmentosum D ortholog K10844|1|0.0|1511|dsi:Dsim_GD11571|DNA excision repair protein ERCC-2 [EC:3.6.1.-] - - - 37374 2818.37 1.51 2.21 0.549497820066353 Up 0.260566635847312 CG9313 CG9313, isoform C K10409|1|0.0|1297|dme:Dmel_CG9313|dynein intermediate chain 1, axonemal - - - 44858 1773.00 0.44 0.475 0.110423989693651 Up 0.0557059833575485 sad shadow K10722|1|0.0|988|dme:Dmel_CG14728|CYP315A1; ecdysteroid 2-hydroxylase GO:0043231//intracellular membrane-bounded organelle GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity GO:0008205//ecdysone metabolic process;GO:0048565//digestive tract development;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development 2768682 1152.00 11.065 18.515 0.742691098370618 Up 0.612732796196011 CG33340 CG33340 - - - - 33128 2114.36 17.135 18.32 0.0964733115777698 Up 0.198355567296262 CG14621 CG14621, isoform D - GO:0031224//intrinsic to membrane - - 41028 1036.00 17.35 17.985 0.0518584966697564 Up 0.12372870162462 mRpL19 mitochondrial ribosomal protein L19 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity GO:0010467//gene expression 12798076 1708.15 1.905 2.15 0.174545662096138 Up 0.119270902126535 40417 826.00 1.81 0.775 -1.22372148180897 Down 0.361874257033417 CG14569 CG14569 - - - - 35832 5372.60 8.79 11.415 0.376995789081298 Up 0.426000528331792 mtt mangetout, isoform G K04611|1|0.0|1445|dme:Dmel_CG30361|glutamate receptor, metabotropic, invertebrate GO:0043005//neuron projection;GO:0031224//intrinsic to membrane;GO:0043005//neuron projection;GO:0031224//intrinsic to membrane;GO:0043005//neuron projection;GO:0031224//intrinsic to membrane;GO:0043005//neuron projection;GO:0031224//intrinsic to membrane GO:0016597//amino acid binding;GO:0004888//transmembrane signaling receptor activity;GO:0016597//amino acid binding;GO:0004888//transmembrane signaling receptor activity;GO:0016597//amino acid binding;GO:0004888//transmembrane signaling receptor activity;GO:0016597//amino acid binding;GO:0004888//transmembrane signaling receptor activity GO:0007631//feeding behavior;GO:0009636//response to toxic substance;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007631//feeding behavior;GO:0009636//response to toxic substance;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007631//feeding behavior;GO:0009636//response to toxic substance;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007631//feeding behavior;GO:0009636//response to toxic substance;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 117414 496.61 40.41 40.51 0.00356573350297756 Up 0.0452714304583278 mRpS14 mitochondrial ribosomal protein S14, isoform B K11984|1|2e-18|90.9|hmg:100212671|U4/U6.U5 tri-snRNP-associated protein 1 GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 33820 1363.00 0.17 0.285 0.745427172914402 Up 0.109926033549069 CG14000 CG14000 - - - - 318846 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG31611 histone H4 K11254|1|4e-40|163|dan:Dana_GF20391|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 317936 1767.00 0.025 0.03 0.263034405833794 Up 0.0467903843613789 CG32246 CG32246 - - - GO:0051234//establishment of localization 43171 1432.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 CG14551 CG14551, isoform B - - - - 37991 1380.48 3.68 2.415 -0.60768257722124 Down 0.352265222559768 CG3770 CG3770, isoform B - GO:0043296//apical junction complex - GO:0021782//glial cell development 39003 1179.00 0.59 0.66 0.161751069996612 Up 0.0708955223880597 CG6576 CG6576 K12605|1|2e-14|80.1|ame:552826|CCR4-NOT transcription complex subunit 2 - - - 43234 1169.00 0.07 0.165 1.23703919730085 Up 0.103949280147933 ro rough, isoform B K09362|1|3e-134|478|dme:Dmel_CG6348|homeo domain only family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0043704//photoreceptor cell fate specification;GO:0010468//regulation of gene expression;GO:0045679;GO:0001752//compound eye photoreceptor fate commitment;GO:0006351//transcription, DNA-dependent;GO:0043704//photoreceptor cell fate specification;GO:0010468//regulation of gene expression;GO:0045679;GO:0001752//compound eye photoreceptor fate commitment;GO:0006351//transcription, DNA-dependent 40537 1067.00 0.37 0.315 -0.232173442129033 Down 0.0666688680491349 TwdlV TweedleV - - - - 40746 899.00 4.715 3.03 -0.637939977202146 Down 0.400904768194426 Obp83cd Odorant-binding protein 83cd - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 42080 7331.27 0.19 0.28 0.559427408614019 Up 0.0934156650376436 Mur89F mucin related 89F, isoform C K01183|1|2e-07|59.7|dme:Dmel_CG2989|chitinase [EC:3.2.1.14];K08827|5|8e-06|54.3|ame:725406|serine/threonine-protein kinase PRP4 [EC:2.7.11.1] - - - 31589 3828.00 2.545 2.675 0.0718732352128141 Up 0.0746598864086646 dx deltex K06058|1|0.0|1137|dme:Dmel_CG3929|deltex - - - 36973 1315.81 178.125 111.455 -0.676428675149852 Down 0.684618940694756 CG4847 CG4847, isoform E K01371|1|0.0|716|dme:Dmel_CG4847|cathepsin K [EC:3.4.22.38];K01365|3|7e-67|254|dmo:Dmoj_GI21205|cathepsin L [EC:3.4.22.15] - - - 48338 840.00 0.33 0.435 0.398549376490275 Up 0.0941421212521464 GstD5 glutathione S transferase D5 K00799|1|8e-124|442|dme:Dmel_CG12242|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity - 44261 4108.89 25.68 26.62 0.0518653687895887 Up 0.134658565579184 eIF5B eIF5B, isoform F K03243|1|0.0|1325|dme:Dmel_CG10840|translation initiation factor IF-2 unclassified subunit - GO:0017111//nucleoside-triphosphatase activity;GO:0004779//sulfate adenylyltransferase activity;GO:0032561//guanyl ribonucleotide binding;GO:0008135//translation factor activity, nucleic acid binding - 33764 511.00 2.88 2.03 -0.504589084257136 Down 0.281633866067891 TotM turandot M, isoform B - GO:0044421//extracellular region part - GO:0006952//defense response 19835837 814.00 5.525 6.91 0.322711246109465 Up 0.323008849557522 36779 1758.00 1.04 0.7 -0.571156701196126 Down 0.178840311715757 Jhedup juvenile hormone esterase duplication K01044|1|0.0|1138|dme:Dmel_CG8424|carboxylesterase [EC:3.1.1.1];K01063|3|2e-104|379|dme:Dmel_CG8425|juvenile-hormone esterase [EC:3.1.1.59];K03927|4|2e-65|250|api:100162163|carboxylesterase type B [EC:3.1.1.1] - GO:0003824//catalytic activity - 42466 1951.00 65.135 61.505 -0.0827292794907643 Down 0.208823140932506 CG17273 adenylosuccinate synthetase K01939|1|0.0|872|dme:Dmel_CG17273|adenylosuccinate synthase [EC:6.3.4.4] GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032561//guanyl ribonucleotide binding GO:0006163//purine nucleotide metabolic process 43103 543.47 909.05 1030.275 0.180597918053958 Up 0.404206841896711 RpL27 ribosomal protein L27, isoform D K02901|1|6e-59|227|dya:Dyak_GE10675|large subunit ribosomal protein L27e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 33824 1689.75 686.335 525.39 -0.385524186293969 Down 0.599854708757099 Gpdh glycerol 3 phosphate dehydrogenase, isoform G K00006|1|0.0|656|dya:Dyak_GE25734|glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0048037//cofactor binding GO:0008344//adult locomotory behavior;GO:0006072//glycerol-3-phosphate metabolic process;GO:0022904//respiratory electron transport chain;GO:0006639//acylglycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0006072//glycerol-3-phosphate metabolic process;GO:0022904//respiratory electron transport chain;GO:0006639//acylglycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0006072//glycerol-3-phosphate metabolic process;GO:0022904//respiratory electron transport chain;GO:0006639//acylglycerol metabolic process 39050 925.12 87.575 88.565 0.0162175897648876 Up 0.0880993263769647 Dhpr dihydropteridine reductase, isoform B K00357|1|1e-120|432|dme:Dmel_CG4665|dihydropteridine reductase [EC:1.5.1.34] - GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0008152//metabolic process;GO:0008152//metabolic process 42864 712.00 1.465 0.21 -2.80243943164349 Down 0.443831726324132 Npc2f Niemann-Pick type C-2f K13443|1|7e-08|57.4|bfo:BRAFLDRAFT_264236|Niemann-Pick C2 protein - - - 12798015 511.00 0.335 0.01 -5.06608919045777 Down 0.286388852199181 39818 5343.13 18.215 17.1 -0.0911306699695218 Down 0.184949148064985 roq roquin, isoform C - - GO:0046914//transition metal ion binding - 43370 975.00 0.48 0.225 -1.09310940439148 Down 0.17481178179897 CG12516 CG12516 - - - - 43518 6905.70 11.205 13.065 0.221564475809628 Up 0.318187821952186 ca claret, isoform C K11494|1|3e-13|79.0|oaa:100083518|RCC1 and BTB domain-containing protein - - GO:0048753//pigment granule organization;GO:0006810//transport 32114 5039.42 8.385 8.885 0.0835609924643319 Up 0.135153876634526 Met Methoprene-tolerant, isoform B K02296|1|3e-13|78.2|mdo:100021673|aryl hydrocarbon receptor nuclear translocator-like protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0060089;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0019840//isoprenoid binding GO:0023060;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 43116 585.00 0.35 0.39 0.156119201917282 Up 0.0596684718002906 CG31093 CG31093 - - - - 32616 2213.34 15.41 14.415 -0.0962960250198789 Down 0.18802007660811 rngo rings lost, isoform B K11885|1|0.0|831|dme:Dmel_CG4420|DNA damage-inducible protein 1 - - GO:0019538//protein metabolic process 38045 3411.00 35.475 29.335 -0.274179692276549 Down 0.449049002773742 Tudor-SN Tudor-SN, isoform B K13221|1|2e-70|268|spu:594312|methylosome protein 50;K08286|3|4e-14|80.9|bfo:BRAFLDRAFT_118019|protein-serine/threonine kinase [EC:2.7.11.-] GO:0044444//cytoplasmic part;GO:0031332;GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0016787//hydrolase activity GO:0035194//posttranscriptional gene silencing by RNA 41967 2126.00 52.36 55 0.0709665213541436 Up 0.18709549597147 CG6126 CG6126 K08202|1|6e-93|342|dan:Dana_GF16120|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - - 3355135 1841.54 33.755 29.78 -0.180757465011625 Down 0.347840443798706 Stlk Ste20-like kinase, isoform C K08271|1|8e-44|178|api:100167545|protein kinase LYK5 - GO:0004672//protein kinase activity;GO:0032559 GO:0031323//regulation of cellular metabolic process;GO:0016310//phosphorylation;GO:0006464//cellular protein modification process 3772619 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33848 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 14462379 428.00 1.105 0.96 -0.202940058670275 Down 0.093778893144895 44360 833.00 59.06 52.31 -0.175094586455958 Down 0.369931316866992 Rab18 Rab18 K07910|1|1e-100|365|dme:Dmel_CG3129|Ras-related protein Rab-18 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005515//protein binding;GO:0032559 GO:0065008;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0006351//transcription, DNA-dependent 39599 616.00 1.56 2.18 0.482782105914678 Up 0.239202218993528 CG13477 CG13477 - - - - 12798123 663.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 37562 2788.22 26.81 28.16 0.0708761146547363 Up 0.170783251882182 qkr58E-2 quaking related 58E-2, isoform C K13198|1|2e-32|141|mdo:100025483|KH domain-containing, RNA-binding, signal transduction-associated protein 1 - - - 40635 785.00 0.71 1.04 0.55069259863641 Up 0.17527407211729 Tim17b1 Tim17b1 K10836|1|4e-74|277|dme:Dmel_CG1158|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0016020//membrane GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting 38683 875.00 30.21 35.27 0.223415391698311 Up 0.397899881125347 Jon65Aiii jonah 65Aiii K01310|1|2e-82|305|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|4|3e-69|261|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32016 2272.00 0.825 1 0.277533975528909 Up 0.110091137234183 sofe sister of feo, isoform B - GO:0044430//cytoskeletal part - GO:0022402//cell cycle process;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0032506 32323 1209.00 1.855 2.59 0.481532911065751 Up 0.259873200369832 CG11164 CG11164, isoform B K10744|1|0.0|640|dme:Dmel_CG11164|ribonuclease H2 subunit B GO:0043231//intracellular membrane-bounded organelle - - 35631 1328.29 0.81 0.735 -0.14017765804826 Down 0.0730748910315678 CG12831 CG12831, isoform C - - - - 35219 1032.00 1.84 2.935 0.673654737053039 Up 0.332749966979263 CG13085 CG13085, isoform B - - - - 37196 5019.00 14.13 16.465 0.220641046261408 Up 0.34117025492009 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A K04164|1|0.0|1243|dme:Dmel_CG16720|5-hydroxytryptamine (serotonin) receptor, invertebrate - - - 38324 3393.96 3.65 4.495 0.300424651747068 Up 0.253335094439308 CG12182 CG12182, isoform C K11310|1|0.0|1347|dme:Dmel_CG12182|general transcription factor 3C polypeptide 4 [EC:2.3.1.48] - GO:0005488//binding - 4379907 1710.68 6.24 7.045 0.175053677447388 Up 0.214502707700436 Mkp MAP kinase-specific phosphatase, isoform D K01090|1|1e-109|396|dme:Dmel_CG34099|protein phosphatase [EC:3.1.3.16];K01104|2|8e-25|114|cfa:488433|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0016866//intramolecular transferase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process;GO:0006464//cellular protein modification process;GO:0001522//pseudouridine synthesis;GO:0006796//phosphate-containing compound metabolic process;GO:0006399//tRNA metabolic process;GO:0006464//cellular protein modification process;GO:0001522//pseudouridine synthesis;GO:0006796//phosphate-containing compound metabolic process 31251 4491.25 9.545 8.335 -0.195562998417521 Down 0.26436402060494 per period, isoform B K02633|1|0.0|1791|dme:Dmel_CG2647|period circadian protein - - - 36281 1373.60 19.92 21.03 0.0782312026636985 Up 0.175108968432175 rho-7 rhomboid-7, isoform B K09650|1|0.0|715|dme:Dmel_CG8972|rhomboid-like protein [EC:3.4.21.105] GO:0031224//intrinsic to membrane - GO:0006944//cellular membrane fusion 41375 1613.00 25.26 33.035 0.387140705589722 Up 0.535068022718267 CG5281 CG5281 - GO:0016020//membrane - - 19835153 543.00 0.305 0.435 0.512206158285842 Up 0.108671245542201 246541 2470.00 0.045 0.135 1.58496250072116 Up 0.107218333113195 CG30325 CG30325 K09566|1|5e-06|53.5|mmu:228005|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8] - - - 36311 1751.00 9.86 11.05 0.164386817900883 Up 0.243329811121384 wash washout, isoform B - GO:0044464//cell part - GO:0002165//instar larval or pupal development;GO:0007292//female gamete generation;GO:0045010//actin nucleation;GO:0009653//anatomical structure morphogenesis 32163 1625.54 16.73 12.705 -0.397041069984998 Down 0.481475366530181 CG1806 CG1806, isoform B - - - - 14462700 1398.00 0.085 0.215 1.33880191345176 Up 0.124917448157443 37875 1530.00 15.545 13.64 -0.188606972316891 Down 0.303790780610223 CG3362 cytosolic 5'-nucleotidase IIIB K01081|1|4e-156|551|dpo:Dpse_GA17406|5'-nucleotidase [EC:3.1.3.5] GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0008252//nucleotidase activity GO:0044238//primary metabolic process 41959 1017.10 189.18 214.02 0.177986045783477 Up 0.395753533218861 CG5903 CG5903, isoform B - - - - 40627 960.00 832.37 1168.785 0.489712694062406 Up 0.645456346585656 rtp retinophilin K04575|1|9e-12|70.9|tca:100142202|amyotrophic lateral sclerosis 2 (juvenile) - - - 19834980 811.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 39762 2900.00 3.415 4.225 0.307065762879456 Up 0.250726456214503 CG5414 CG5414 K01870|1|0.0|1889|dme:Dmel_CG5414|isoleucyl-tRNA synthetase [EC:6.1.1.5] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0046914//transition metal ion binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 39601 1407.30 0.875 1.085 0.31034012061215 Up 0.125478800686831 CG17177 CG17177, isoform B K11498|1|7e-22|107|mcc:711186|centromeric protein E - - - 47080 3846.80 3.575 3.85 0.106915203916512 Up 0.111312904504029 acj6 abnormal chemosensory jump 6, isoform N K09366|1|2e-179|629|dme:Dmel_CG9151|POU domain transcription factor, class 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004721//phosphoprotein phosphatase activity GO:0008038//neuron recognition;GO:0007630//jump response;GO:0010468//regulation of gene expression;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006351//transcription, DNA-dependent;GO:0008038//neuron recognition;GO:0007630//jump response;GO:0010468//regulation of gene expression;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006351//transcription, DNA-dependent;GO:0008038//neuron recognition;GO:0007630//jump response;GO:0010468//regulation of gene expression;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006351//transcription, DNA-dependent;GO:0008038//neuron recognition;GO:0007630//jump response;GO:0010468//regulation of gene expression;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006351//transcription, DNA-dependent;GO:0008038//neuron recognition;GO:0007630//jump response;GO:0010468//regulation of gene expression;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006928//cellular component movement;GO:0006351//transcription, DNA-dependent 33782 3161.94 10.26 12.455 0.279694290633782 Up 0.36596882842425 Lam lamin, isoform D K07611|1|0.0|965|dme:Dmel_CG6944|lamin B GO:0034399//nuclear periphery;GO:0015630//microtubule cytoskeleton;GO:0005882//intermediate filament;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0005488//binding GO:0000278//mitotic cell cycle;GO:0016458//gene silencing;GO:0003006//developmental process involved in reproduction;GO:0040023//establishment of nucleus localization;GO:0048592//eye morphogenesis;GO:0006997//nucleus organization;GO:0042335//cuticle development;GO:0060446//branching involved in open tracheal system development;GO:0007399//nervous system development 35989 1341.00 11.915 14.795 0.31233074500365 Up 0.412429005415401 CG1827 CG1827 K01444|1|0.0|778|dsi:Dsim_GD10667|N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26] GO:0000323//lytic vacuole GO:0004067//asparaginase activity GO:0006464//cellular protein modification process 36843 657.00 0.69 0.21 -1.71620703399941 Down 0.263802668075551 CG15712 CG15712 - - - - 5740811 1494.00 6.245 7.24 0.213288125475248 Up 0.246367718927486 CG34231 CG34231 - - GO:0005488//binding - 44484 7186.00 5.355 7.22 0.431112262136915 Up 0.387696473385286 Glu-RIB glutamate receptor IB, isoform C K05313|1|0.0|1884|dme:Dmel_CG4481|glutamate receptor, ionotropic, invertebrate GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 34339 1428.00 3.275 4.665 0.510382174426946 Up 0.355897503632281 Spn31A serpin 31A K13963|1|1e-32|140|dwi:Dwil_GK20885|serpin B - GO:0004866//endopeptidase inhibitor activity - 3772518 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33851 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 38027 11502.11 7.08 8.095 0.193281720219568 Up 0.240556069211465 rno rhinoceros, isoform D K11347|1|4e-135|484|mdo:100011405|protein Jade-1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046872//metal ion binding GO:0006351//transcription, DNA-dependent;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation;GO:0006351//transcription, DNA-dependent;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation 19835412 283.00 0.35 0.825 1.23703919730085 Up 0.24907541936336 31054 3972.20 61.86 70.98 0.19840574097168 Up 0.403084136837934 su(w[a]) suppressor of white-apricot, isoform M - - GO:0003676//nucleic acid binding GO:0010467//gene expression 14462478 1153.00 8.435 8.82 0.0643905872699549 Up 0.111940298507463 40538 1322.01 18.345 12.535 -0.549424908414603 Down 0.559470347378153 CG1092 CG1092, isoform D - - - - 34872 2215.38 33.89 15.35 -1.14262098122645 Down 0.704695548804649 mol moladietz, isoform G - GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0008104//protein localization;GO:0008306//associative learning;GO:0006810//transport;GO:0008104//protein localization;GO:0008306//associative learning;GO:0006810//transport;GO:0008104//protein localization;GO:0008306//associative learning;GO:0006810//transport;GO:0008104//protein localization;GO:0008306//associative learning;GO:0006810//transport;GO:0008104//protein localization;GO:0008306//associative learning;GO:0006810//transport 19835590 609.00 1.05 0.825 -0.347923303420307 Down 0.131422533350944 - CG45491 - - - - 33668 3034.00 0.385 0.965 1.32567049657318 Up 0.279157310791177 CG11929 CG11929, isoform B K11499|1|3e-07|58.2|bta:533089|centromere protein F - - - 33942 2116.91 18.96 14.365 -0.400400971365735 Down 0.49455157839123 GRHR adipokinetic hormone receptor, isoform D K04280|1|0.0|816|dya:Dyak_GE18412|gonadotropin-releasing hormone receptor GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016500//protein-hormone receptor activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity;GO:0008528//G-protein coupled peptide receptor activity GO:0006629//lipid metabolic process;GO:0055088//lipid homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0006629//lipid metabolic process;GO:0055088//lipid homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0006629//lipid metabolic process;GO:0055088//lipid homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0023060 19834938 290.00 0.175 0.355 1.02046410255972 Up 0.14377228899749 38223 1852.52 39.865 13.59 -1.55257721299832 Down 0.741513670585127 Cht2 chitinase 2, isoform C K01183|1|0.0|937|dme:Dmel_CG2054|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding GO:0006032//chitin catabolic process 43182 4453.00 13.405 10.9 -0.298443084318273 Down 0.392187293620394 CG12290 CG12290, isoform B K04150|1|2e-06|55.5|ecb:100058810|histamine receptor H2 GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway 43648 602.94 289.11 217.89 -0.408018525036272 Down 0.605138026680756 Npc2g Niemann-Pick type C-2g, isoform B K13443|1|4e-74|277|dse:Dsec_GM12131|Niemann-Pick C2 protein - - - 47121 2917.94 2.785 1.99 -0.484908896796383 Down 0.271694624224013 dup double parked, isoform B K10727|1|0.0|1296|dme:Dmel_CG8171|chromatin licensing and DNA replication factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex GO:0003676//nucleic acid binding GO:0006277//DNA amplification;GO:0006261//DNA-dependent DNA replication;GO:0051297//centrosome organization;GO:0006959//humoral immune response;GO:0051304//chromosome separation;GO:0051301//cell division;GO:0007165//signal transduction 35927 2450.63 24.41 24.585 0.010306060039461 Up 0.0600977413815876 Su(var)2-10 suppressor of variegation 2-10, isoform N K04706|1|0.0|942|dsi:Dsim_GD10632|protein inhibitor of activated STAT GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery;GO:0000781//chromosome, telomeric region;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0001654//eye development;GO:0051276//chromosome organization;GO:0009894;GO:0048534;GO:0007444//imaginal disc development;GO:0010741//negative regulation of intracellular protein kinase cascade 31940 3072.26 20.435 27.455 0.426026667923606 Up 0.542992999603751 CG15312 CG15312, isoform F - - - - 36126 2003.00 3.26 3.99 0.291516781991268 Up 0.233885880332849 CG12309 CG12309 K01672|1|0.0|905|dme:Dmel_CG12309|carbonic anhydrase [EC:4.2.1.1] - - - 5740443 967.00 0.165 0.17 0.0430687218918859 Up 0.0418702945449742 32872 2134.92 190.765 165.54 -0.204616639225727 Down 0.422170122837142 bnb bangles and beads, isoform D - - - GO:0022008//neurogenesis;GO:0022008//neurogenesis;GO:0022008//neurogenesis;GO:0022008//neurogenesis 3771806 5005.00 0.135 0.14 0.0524674198941355 Up 0.0419363360190199 mei-217 mei-217 - GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0032559 GO:0006310//DNA recombination 31474 1300.65 91.945 101.98 0.149443215437323 Up 0.341797648923524 Mlc-c myosin light chain cytoplasmic, isoform B K12752|1|5e-79|295|dya:Dyak_GE16807|myosin light chain, invertebrate - - - 3885601 545.00 6.64 15.51 1.22394353968917 Up 0.667778364813103 CG34054 CG34054 - - - - 36268 16988.00 1.14 1.16 0.0250909809628305 Up 0.0445449742438251 CG13185 CG13185 K10413|1|3e-08|63.9|aag:AaeL_AAEL007132|dynein heavy chain 1, cytosolic;K10414|5|4e-07|60.1|smm:Smp_165620|dynein heavy chain 2, cytosolic - GO:0004175//endopeptidase activity;GO:0016887//ATPase activity;GO:0032559 GO:0019538//protein metabolic process;GO:0012501//programmed cell death 40086 1008.00 0.395 0.53 0.424139706386096 Up 0.109562805441817 CG14079 CG14079 - - - - 41884 4502.07 0.02 0.03 0.584962500721156 Up 0.047450799101836 CG6118 CG6118, isoform D K09237|1|1e-26|122|dgr:Dgri_GH18647|Cys2His2 zinc finger developmental/cell cycle regulator, other - - - 35163 4237.00 0.09 0.095 0.0780025120012732 Up 0.0426627922335227 CG31792 CG31792, isoform C K05673|1|0.0|1373|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|2|0.0|1218|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane GO:0015405;GO:0005253//anion channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 40702 1615.65 0.265 0.265 0 - 0.0382380134724607 CG2104 CG2104, isoform B - - GO:0008047//enzyme activator activity - 5740168 627.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 CG34456 CG34456 - - - - 37805 1653.62 92.415 93.72 0.0202299178272984 Up 0.0895522388059701 G-salpha60A G protein alpha s subunit, isoform E K04632|1|0.0|740|dsi:Dsim_GD11812|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane;GO:0019897//extrinsic to plasma membrane GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0007166//cell surface receptor signaling pathway;GO:0048741//skeletal muscle fiber development;GO:0007267//cell-cell signaling;GO:0034285;GO:0045762//positive regulation of adenylate cyclase activity;GO:0050909//sensory perception of taste;GO:0030534//adult behavior;GO:0023060;GO:0007472//wing disc morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0048741//skeletal muscle fiber development;GO:0007267//cell-cell signaling;GO:0034285;GO:0045762//positive regulation of adenylate cyclase activity;GO:0050909//sensory perception of taste;GO:0030534//adult behavior;GO:0023060;GO:0007472//wing disc morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0048741//skeletal muscle fiber development;GO:0007267//cell-cell signaling;GO:0034285;GO:0045762//positive regulation of adenylate cyclase activity;GO:0050909//sensory perception of taste;GO:0030534//adult behavior;GO:0023060;GO:0007472//wing disc morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0048741//skeletal muscle fiber development;GO:0007267//cell-cell signaling;GO:0034285;GO:0045762//positive regulation of adenylate cyclase activity;GO:0050909//sensory perception of taste;GO:0030534//adult behavior;GO:0023060;GO:0007472//wing disc morphogenesis 34813 1286.79 6.38 6.585 0.0456270164916449 Up 0.0838726720380399 nimB1 nimrod B1, isoform B K06252|1|5e-20|99.0|oaa:100076692|tenascin - - - 40389 723.78 147.995 109.485 -0.434815208502281 Down 0.608109893012812 VhaM9.7-b vacuolar H[+] ATPase M9.7 subunit b, isoform B K02153|1|5e-49|194|dme:Dmel_CG7625|V-type H+-transporting ATPase subunit H [EC:3.6.3.14] GO:0033176 GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient 36652 2024.00 7.205 8.41 0.223107370080397 Up 0.272421080438515 CG10209 CG10209, isoform B - - - - 19835248 2969.00 6.1 5.215 -0.226141989930483 Down 0.238211596882842 42446 4439.70 16.615 15.6 -0.0909402639424209 Down 0.180425307092854 Pi3K92E Pi3K92E, isoform C K00922|1|0.0|2149|dme:Dmel_CG4141|phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153] GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005942//phosphatidylinositol 3-kinase complex GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035004//phosphatidylinositol 3-kinase activity GO:0022611//dormancy process;GO:0048812//neuron projection morphogenesis;GO:0045570//regulation of imaginal disc growth;GO:0006412//translation;GO:0030384;GO:0008283//cell proliferation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0021700//developmental maturation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0001700//embryonic development via the syncytial blastoderm;GO:0030537//larval behavior;GO:0007292//female gamete generation;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0019932//second-messenger-mediated signaling;GO:0044248//cellular catabolic process;GO:0022611//dormancy process;GO:0048812//neuron projection morphogenesis;GO:0045570//regulation of imaginal disc growth;GO:0006412//translation;GO:0030384;GO:0008283//cell proliferation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0021700//developmental maturation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0001700//embryonic development via the syncytial blastoderm;GO:0030537//larval behavior;GO:0007292//female gamete generation;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0019932//second-messenger-mediated signaling;GO:0044248//cellular catabolic process 35984 1925.75 52.42 60.08 0.196767459185854 Up 0.397140404173821 CG1814 CG1814, isoform C K11757|1|6e-114|411|ecb:100051687|protein polybromo-1;K01081|2|9e-49|194|cin:100183021|5'-nucleotidase [EC:3.1.3.5] - - - 8674093 685.00 0.755 0.455 -0.730610099126383 Down 0.175108968432175 Sfp84E seminal fluid protein 84E - - - - 47208 1469.00 0.01 0.04 2 Up 0.0694426099590543 term terminus - GO:0044464//cell part GO:0046914//transition metal ion binding - 36202 1346.00 1.53 1.8 0.234465253637023 Up 0.13102628450667 CG18335 CG18335 - - - - 37706 2034.00 14 9.41 -0.573160199103792 Down 0.537181349887729 eIF2B-delta eIF2B-delta, isoform D K03680|1|0.0|799|dse:Dsec_GM16009|translation initiation factor eIF-2B delta subunit GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 19834993 1215.00 3.82 6.375 0.738852703710472 Up 0.482036719059569 19835014 2186.00 16.86 16.445 -0.0359555281066799 Down 0.102595429929996 36471 819.77 852.655 877.74 0.0418315362432242 Up 0.140338132347114 CG4716 CG4716, isoform C - - - - 42146 1607.00 18.36 16.25 -0.176126340610629 Down 0.305639941883503 CG18012 CG18012, isoform C K03842|1|0.0|911|dme:Dmel_CG18012|beta-1,4-mannosyltransferase [EC:2.4.1.142] - - - 8674012 457.00 0.285 0.615 1.1096244911745 Up 0.200633998150839 CG42521 CG42521 - - - - 5740656 344.00 0.01 0.175 4.12928301694497 Up 0.187062475234447 CG34278 CG34278 - - - - 14462780 820.00 0.055 0.275 2.32192809488736 Up 0.18026020340774 31397 1424.00 0.635 0.645 0.0225425686510882 Up 0.0413749834896315 HLH4C helix loop helix protein 4C, isoform B K09075|1|9e-52|204|dpo:Dpse_GA15893|nescient helix-loop-helix protein GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity - 44786 3208.00 0.085 0.25 1.55639334852439 Up 0.14109760929864 nerfin-1 nervous fingers 1 K09228|1|5e-10|67.4|bta:517970|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006355//regulation of transcription, DNA-dependent;GO:0006935//chemotaxis;GO:0045165//cell fate commitment;GO:0048812//neuron projection morphogenesis 31721 1480.00 944.455 508.285 -0.893844402806636 Down 0.726423193765685 CG2233 CG2233 - - - - 39981 1585.38 14.4 13.465 -0.0968545818280029 Down 0.183859463743231 cln3 cln3, isoform B K12389|1|0.0|848|dme:Dmel_CG5582|battenin GO:0044464//cell part - GO:0007219//Notch signaling pathway;GO:0043408//regulation of MAPK cascade 117348 1417.00 0.085 0.04 -1.08746284125034 Down 0.0796790384361379 Gr28a gustatory receptor 28a K08471|1|0.0|754|dme:Dmel_CG13787|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33346 1636.36 26.445 23.955 -0.142668161908949 Down 0.282921674811782 cpb capping protein beta, isoform B K10365|1|1e-158|560|dya:Dyak_GE17670|capping protein (actin filament) muscle Z-line, beta GO:0033011//perinuclear theca;GO:0015629//actin cytoskeleton;GO:0031252//cell leading edge;GO:0043234//protein complex GO:0008092//cytoskeletal protein binding GO:0030032//lamellipodium assembly;GO:0007444//imaginal disc development;GO:0030835//negative regulation of actin filament depolymerization;GO:0007297//ovarian follicle cell migration;GO:0007300//ovarian nurse cell to oocyte transport 37461 5069.00 17.415 19.375 0.15386583746224 Up 0.276680755514463 PTP-ER protein tyrosine phosphatase-ERK/Enhancer of Ras1 K01104|1|0.0|2447|dme:Dmel_CG9856|protein-tyrosine phosphatase [EC:3.1.3.48] - - - 35193 1821.00 3.285 3.605 0.134105888918493 Up 0.127030775326905 l(2)37Cd lethal (2) 37Cd - - - - 38975 954.00 9.805 10.975 0.162631404230571 Up 0.241711795007265 GstO1 glutathione S transferase O1 K00310|1|5e-72|271|dme:Dmel_CG6781|pyrimidodiazepine synthase [EC:1.5.4.1];K00799|1|5e-72|271|dme:Dmel_CG6781|glutathione S-transferase [EC:2.5.1.18] GO:0044424//intracellular part GO:0042802//identical protein binding;GO:0016648;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0019889//pteridine metabolic process;GO:0042441//eye pigment metabolic process 36567 1026.44 6.93 9.02 0.380272081118167 Up 0.394663848897107 CG18327 CG18327, isoform B K03454|1|2e-125|448|dpo:Dpse_GA20987|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 49805 1520.96 37.075 38.32 0.0476508683941872 Up 0.141725003302074 Spn42Da serpin 42Da, isoform L K13963|1|2e-132|472|dgr:Dgri_GH19862|serpin B - GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing;GO:0010466//negative regulation of peptidase activity;GO:0010955//negative regulation of protein processing 5740544 21964.35 30.525 44.095 0.530623780430378 Up 0.612501651036851 futsch futsch, isoform F K10429|1|0.0|1626|dse:Dsec_GM19138|microtubule-associated protein 1 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0048638//regulation of developmental growth;GO:0048812//neuron projection morphogenesis;GO:0010970//microtubule-based transport;GO:0045104//intermediate filament cytoskeleton organization;GO:0008306//associative learning;GO:0048513//organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0043066//negative regulation of apoptotic process;GO:0048638//regulation of developmental growth;GO:0048812//neuron projection morphogenesis;GO:0010970//microtubule-based transport;GO:0045104//intermediate filament cytoskeleton organization;GO:0008306//associative learning;GO:0048513//organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0043066//negative regulation of apoptotic process 33292 2029.00 4.03 4.085 0.0195562396177159 Up 0.0513472460705323 MFS3 major facilitator superfamily transporter 3 K08193|1|0.0|933|dme:Dmel_CG4726|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport 43788 5569.25 28.025 28.8 0.0393544386368856 Up 0.118016114119667 Hcf host cell factor, isoform G K01787|1|1e-164|582|mcc:698140|N-acylglucosamine 2-epimerase [EC:5.1.3.8];K10317|2|2e-11|73.2|xla:447763|F-box protein 42 - - - 33961 2587.20 4.76 10.78 1.17932369944456 Up 0.631224408928807 Nha1 Na[+]/H[+] hydrogen antiporter 1, isoform B - GO:0042995//cell projection;GO:0031224//intrinsic to membrane;GO:0042995//cell projection;GO:0031224//intrinsic to membrane GO:0015298//solute:cation antiporter activity;GO:0015298//solute:cation antiporter activity GO:0006811//ion transport;GO:0006811//ion transport 38345 1144.00 24.235 23.36 -0.0530518082863829 Down 0.132908466516973 mRpS35 mitochondrial ribosomal protein S35 - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 3354930 1847.32 59.42 55.275 -0.104321485131826 Down 0.245278034605732 CG40191 CG40191, isoform E - - - - 34794 1687.00 1.74 1.845 0.0845335102116677 Up 0.0690133403777572 Orc5 origin recognition complex subunit 5 K02607|1|0.0|876|dme:Dmel_CG7833|origin recognition complex subunit 5 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0000070//mitotic sister chromatid segregation;GO:0016458//gene silencing;GO:0006260//DNA replication 40360 2844.00 10.8 10.73 -0.00938123629430906 Down 0.0513802668075551 CG7338 CG7338 - GO:0043231//intracellular membrane-bounded organelle - GO:0022613//ribonucleoprotein complex biogenesis 40974 1954.00 3.765 4.005 0.0891523777367822 Up 0.0993593977017567 CG9630 CG9630 K01529|1|0.0|1004|dpo:Dpse_GA21925| [EC:3.6.1.-] - GO:0032559;GO:0042623//ATPase activity, coupled - 8673973 491.00 18.33 21.885 0.255735598099161 Up 0.402522784308546 31608 1179.00 7.715 6.995 -0.141342099405982 Down 0.190100383040549 CG3184 CG3184 - - - - 251430 1158.71 18.905 17.55 -0.107296818795312 Down 0.215724474970281 pen-2 presenilin enhancer, isoform B K06170|1|6e-56|215|dme:Dmel_CG33198|presenilin enhancer 2 GO:0016021//integral to membrane;GO:0044446//intracellular organelle part;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0005794//Golgi apparatus GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding GO:0006917//induction of apoptosis;GO:0006516//glycoprotein catabolic process;GO:0051604//protein maturation;GO:0044093;GO:0033619//membrane protein proteolysis 33628 2254.21 39.315 36.03 -0.125881202622783 Down 0.284110421344604 CG3702 CG3702, isoform B - GO:0031224//intrinsic to membrane - - 34997 2205.85 189.015 184.41 -0.0355838386052633 Down 0.136078457271166 VhaSFD vacuolar H[+]-ATPase SFD subunit, isoform E K02144|1|0.0|897|dme:Dmel_CG17332|V-type H+-transporting ATPase 54 kD subunit [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0050658//RNA transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0050658//RNA transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process;GO:0050658//RNA transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process 35838 3928.33 7.37 9.545 0.373080578308868 Up 0.397074362699775 CG42326 CG42326, isoform E - - - - 32737 1901.44 48.28 50.69 0.0702754878344549 Up 0.185081231013076 CG8408 stasimon, isoform B - - - - 35691 8512.00 12.245 14.65 0.258707890745632 Up 0.365242372209748 Corin corin, isoform C K09614|1|0.0|2331|dme:Dmel_CG2105|corin [EC:3.4.21.-] GO:0044464//cell part GO:0004175//endopeptidase activity;GO:0004888//transmembrane signaling receptor activity GO:0019538//protein metabolic process 42751 974.78 7.91 4.235 -0.901315725140593 Down 0.54946506406023 CG13827 CG13827, isoform B K13353|1|4e-131|467|dme:Dmel_CG13827|peroxin-11C - - GO:0007031//peroxisome organization 42876 3590.00 8.03 7.1 -0.17758096312527 Down 0.228602562409193 CG5524 java no jive K10352|1|8e-24|113|aga:AgaP_AGAP007523|myosin heavy chain GO:0043232 GO:0032559 - 39221 629.00 29.945 33.17 0.147563879809635 Up 0.306696605468234 CG7949 CG7949 - - - - 35891 1220.00 13.795 15.685 0.18524007249033 Up 0.303460573239995 CG8237 CG8237 - - - - 38782 404.00 0.12 0.01 -3.58496250072116 Down 0.14562145027077 CG15829 CG15829, isoform B K08762|1|7e-13|72.0|xla:444376|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) - GO:0005504//fatty acid binding;GO:0008144//drug binding;GO:0030234//enzyme regulator activity - 12797999 1283.00 0.25 0.17 -0.556393348524385 Down 0.0892550521727645 36733 1483.00 0.16 0.175 0.129283016944966 Up 0.0491348566900013 CG8214 centrosomal protein 89kDa homolog - - - - 326136 661.00 0.125 0.07 -0.83650126771712 Down 0.07657508915599 Npc2e Niemann-Pick type C-2e K13443|1|1e-16|85.5|aga:AgaP_AGAP002851|Niemann-Pick C2 protein - GO:0046914//transition metal ion binding - 19834892 280.00 16.215 47.735 1.55771843552545 Up 0.747160216616035 - CG45080 - - - - 37754 1704.00 5.63 4.18 -0.429631979999347 Down 0.350944393078854 l(2)not lethal (2) neighbor of tid K03845|1|0.0|851|dme:Dmel_CG4084|alpha-1,3-mannosyltransferase [EC:2.4.1.130] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0016757//transferase activity, transferring glycosyl groups - 32943 4648.01 2.095 2.145 0.0340274038001941 Up 0.0530643243957205 CG32532 CG32532, isoform D K09452|1|7e-17|90.5|dre:30657|homeobox protein aristaless-related;K09329|2|5e-16|87.8|mmu:20204|paired mesoderm homeobox protein;K09451|3|6e-16|87.4|dre:100006399|homeobox protein aristaless-like 4;K09334|4|6e-16|87.4|cfa:482587|cartilage homeoprotein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 42302 1976.00 28.155 24.385 -0.207397178516163 Down 0.372176726984546 CG5555 CG5555, isoform B K10632|1|0.0|1122|dme:Dmel_CG5555|BRCA1-associated protein [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 37949 3113.46 99.9 38.69 -1.36852394923656 Down 0.751188746532823 Mmp1 matrix metalloproteinase 1, isoform L K07763|1|0.0|987|dpo:Dpse_GA18484|matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80] GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part;GO:0043005//neuron projection;GO:0044421//extracellular region part GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0022617//extracellular matrix disassembly;GO:0002164//larval development;GO:0060560//developmental growth involved in morphogenesis;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death;GO:0007560//imaginal disc morphogenesis 33856 870.00 11.48 12.065 0.0717052735400635 Up 0.135616166952846 CG9150 CG9150 K11539|1|4e-20|98.6|dre:402954|carbonyl reductase 4 [EC:1.1.1.-];K00069|4|4e-16|85.1|bfo:BRAFLDRAFT_59751|15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] - GO:0003824//catalytic activity GO:0008152//metabolic process 43951 1008.73 47.67 48.045 0.0113046734261645 Up 0.0656122044644036 e(r) enhancer of rudimentary, isoform E - - - GO:0006220//pyrimidine nucleotide metabolic process;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0006220//pyrimidine nucleotide metabolic process;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0006355//regulation of transcription, DNA-dependent 33343 12168.86 5.08 6.86 0.433380079400647 Up 0.381323471139876 chinmo chronologically inappropriate morphogenesis, isoform H K02174|1|3e-22|108|dme:Dmel_CG11491|broad;K09237|2|1e-21|106|api:100161247|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development 43494 579.98 1417.625 1232.165 -0.202280490162227 Down 0.43234050984018 Obp99c Odorant-binding protein 99c, isoform B - - GO:0005488//binding GO:0051234//establishment of localization 19835501 846.00 13.8 13 -0.0861566437497146 Down 0.167481178179897 34730 1574.00 28.045 23.29 -0.268032943470919 Down 0.432373530577202 CG16820 CG16820 - - - - 5740462 5859.46 25.5 19.94 -0.354831837348025 Down 0.493792101439704 CG34398 CG34398, isoform L - GO:0016020//membrane;GO:0016020//membrane;GO:0031224//intrinsic to membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane - - 19834903 576.00 0.01 0.32 5 Up 0.281666886804913 39771 1393.00 0.14 0.135 -0.0524674198941354 Down 0.0382380134724607 CG5157 CG5157 K10224|1|1e-08|61.2|ssc:444995|fatty acid desaturase 1 (delta-5 desaturase) [EC:1.14.19.-];K10595|2|1e-07|58.2|bfo:BRAFLDRAFT_73255|E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19] GO:0016020//membrane GO:0005506//iron ion binding - 36694 6954.08 17.005 19.22 0.176649330065908 Up 0.309371285167085 trpm transient receptor potential cation channel, subfamily M ortholog, isoform J K04978|1|0.0|1145|dre:565807|transient receptor potential cation channel subfamily M member 3 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 10178950 2818.00 4.615 4.56 -0.0172968234810327 Down 0.0528001584995377 pre-mod(mdg4)-V pre-mod(mdg4)-V - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 39316 974.70 14.965 15.485 0.0492791041765621 Up 0.117454761590279 CG14135 CG14135, isoform C - - GO:0005488//binding - 39267 3255.00 19.73 21.635 0.132976164698333 Up 0.256769251089684 CG7600 CG7600 - - GO:0005488//binding - 30988 775.69 4.71 4.985 0.0818664447854129 Up 0.104807819310527 CG13373 CG13373, isoform B - - - - 33031 759.00 0.73 1.1 0.591535154644642 Up 0.187987055871087 CG12679 CG12679 - - - - 38355 2352.00 18.765 18.515 -0.0193497407153461 Down 0.0730088495575221 CG2107 CG2107 K08766|1|0.0|1301|dme:Dmel_CG2107|carnitine O-palmitoyltransferase 2 [EC:2.3.1.21] GO:0044464//cell part GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 53502 1846.52 4.235 6.205 0.551069240798158 Up 0.416721701228371 Ugt86Di Ugt86Di, isoform B K00699|1|0.0|950|dme:Dmel_CG6658|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 2768933 695.00 1.575 1.54 -0.0324214776923773 Down 0.0473517368907674 CheB38b chemosensory protein B 38b - GO:0044421//extracellular region part GO:0005261//cation channel activity GO:0030001//metal ion transport;GO:0009593//detection of chemical stimulus 38315 1528.09 274.945 240.165 -0.195117132890192 Down 0.425439175802404 CG16758 CG16758, isoform H K03783|1|7e-172|604|dsi:Dsim_GD13387|purine-nucleoside phosphorylase [EC:2.4.2.1] - GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process 19835667 536.51 0.385 0.775 1.00933786457934 Up 0.218267071721041 39121 1398.12 14.065 12.84 -0.131464350192397 Down 0.226819442609959 CG8336 CG8336, isoform D K05864|1|0.0|728|dme:Dmel_CG8336|peptidyl-prolyl isomerase D (cyclophilin D) [EC:5.2.1.8] - GO:0016859//cis-trans isomerase activity;GO:0016859//cis-trans isomerase activity;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 31766 2012.27 31.45 31.18 -0.0124390890688669 Down 0.0631686699247127 CG1636 CG1636, isoform C - - - - 35308 2512.00 4.61 3.63 -0.344797202433587 Down 0.280246995112931 CG16798 CG16798 - - - - 40555 1672.10 12.575 12.025 -0.064521506035485 Down 0.127658169330339 CG14646 CG14646, isoform B - - - - 48581 2382.00 43.615 40.825 -0.0953715038922184 Down 0.23586712455422 Hsp70Aa Heat-shock-protein-70Aa K03283|1|0.0|1147|dme:Dmel_CG18743|heat shock 70kDa protein 1/8 GO:0015630//microtubule cytoskeleton GO:0032559 GO:0034605//cellular response to heat 34714 4077.11 20.555 18.705 -0.136065406013111 Down 0.264000792497689 Edem2 Edem2, isoform B K10086|1|0.0|1645|der:Dere_GG23820|ER degradation enhancer, mannosidase alpha-like 3 GO:0044464//cell part GO:0046872//metal ion binding;GO:0015924 GO:0043161//proteasomal ubiquitin-dependent protein catabolic process 19835298 372.00 0.12 0.285 1.24792751344359 Up 0.142385418042531 39204 816.01 16.755 15.055 -0.154348978479794 Down 0.266576409985471 CG8009 CG8009, isoform B - - - - 4379851 428.00 55.23 55.195 -0.000914545222948317 Down 0.0434552899220711 CG34117 CG34117 - - - - 3772009 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 38589 1960.72 65.83 59.31 -0.150469825968123 Down 0.331032888654075 Rh50 Rh50, isoform C K06579|1|0.0|709|dpo:Dpse_GA20395|Rhesus blood group glycoprotein;K06580|2|5e-86|318|mcc:574120|Rhesus blood group-associated glycoprotein GO:0031224//intrinsic to membrane GO:0015101//organic cation transmembrane transporter activity GO:0006810//transport 32831 1858.16 9.32 8.145 -0.194415256128763 Down 0.257330603619073 CG6361 hayan, isoform D K01312|1|2e-98|359|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4];K01362|3|2e-31|137|dme:Dmel_CG4920| [EC:3.4.21.-];K09628|4|4e-31|135|rno:287108|protease, serine 27 [EC:3.4.21.-];K01344|5|5e-30|132|ecb:100051306|protein C (activated) [EC:3.4.21.69] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0008063//Toll signaling pathway;GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0008063//Toll signaling pathway 19835109 417.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 37518 1062.00 1.215 0.98 -0.310102659490573 Down 0.133634922731475 CG13502 CG13502, isoform D K04460|1|2e-06|54.7|dre:541536|protein phosphatase 5 [EC:3.1.3.16] - - - 3355096 893.00 121.115 116.61 -0.0546860392627326 Down 0.156022982432968 CG40042 CG40042 - GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0022892 GO:0006810//transport 39653 3133.00 12.11 14.365 0.246359127838195 Up 0.353090740985339 FucTA FucTA, isoform B K00753|1|0.0|984|dme:Dmel_CG6869|glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214] GO:0000139//Golgi membrane;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process 32676 1283.00 17.13 9.385 -0.868096501253124 Down 0.629177123233391 CG4872 CG4872 - - - - 14462431 1748.00 0.11 0.125 0.184424571137427 Up 0.045667679302602 41473 3479.02 9.225 12.435 0.430785691269148 Up 0.464271562541276 dpr15 dpr15, isoform B K06550|1|2e-07|58.9|mdo:100028028|L1 cell adhesion molecule - - - 19835067 412.00 0.745 0.76 0.028758992981424 Up 0.0445449742438251 43324 10187.64 44.41 58.1 0.387653592324778 Up 0.563531898031964 CG18437 unc80, isoform G - - - - 246671 1488.00 0.705 0.835 0.244152940075258 Up 0.0941751419891692 Obp57d Odorant-binding protein 57d - - GO:0005198//structural molecule activity;GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 35355 677.74 415.11 401.64 -0.0475907300257918 Down 0.160844010038304 CG9336 CG9336, isoform B K06846|1|6e-06|50.8|dpo:Dpse_GA19698|lymphocyte antigen 6 complex - - - 19834922 239.00 0.2 0.23 0.20163386116965 Up 0.0565645225201427 326255 3755.52 61.45 73.465 0.257644078089734 Up 0.468960507198521 4EHP eIF4E-Homologous protein, isoform D K03259|1|3e-103|375|dse:Dsec_GM23515|translation initiation factor eIF-4E GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0002118//aggressive behavior;GO:0006412//translation;GO:0002118//aggressive behavior;GO:0006412//translation;GO:0002118//aggressive behavior;GO:0006412//translation;GO:0002118//aggressive behavior;GO:0006412//translation 32291 1282.00 0.37 0.26 -0.509013647487857 Down 0.100779289393739 dmrt11E doublesex-Mab related 11E - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction 19835805 313.00 4.77 7.66 0.683355125919446 Up 0.490589089948488 33007 5781.38 6.38 8.32 0.383027104376223 Up 0.384691586316207 D2R dopamine 2-like receptor, isoform J K14049|1|0.0|834|dme:Dmel_CG33517|dopamine D2-like receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004952//dopamine neurotransmitter receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0004952//dopamine neurotransmitter receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 43608 663.54 13.86 13.595 -0.0278511061124538 Down 0.0834434024567428 CG15535 CG15535, isoform B - - - - 14462492 980.00 0.48 0.05 -3.26303440583379 Down 0.277010962884692 31991 9295.10 11.15 15.23 0.449872231679625 Up 0.497985735041606 CG43347 CG43347, isoform D K12463|1|2e-23|112|oaa:100073611|PR domain zinc finger protein 4 GO:0016020//membrane;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding GO:0006810//transport;GO:0006810//transport 318645 1060.00 3.04 3.58 0.235888263820671 Up 0.189439968300092 CG31251 CG31251 - - - - 32588 1485.80 46.565 49.16 0.0782389371913817 Up 0.202549200898164 CG9911 CG9911, isoform D K09582|1|4e-29|129|cel:C14B9.2|protein disulfide-isomerase A4 [EC:5.3.4.1];K08056|5|9e-28|124|mdo:100011727|protein disulfide isomerase family A, member 3 [EC:5.3.4.1] - - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis 5740481 532.00 0.39 0.315 -0.308122295362332 Down 0.0837405890899485 CG34198 CG34198 - - - - 12797994 469.00 0.01 0.4 5.32192809488736 Up 0.31904636111478 326109 1817.00 52.38 57.89 0.144298096878283 Up 0.313498877294941 CG18858 CG18858, isoform B K00650|1|0.0|842|dme:Dmel_CG18858|lecithin-cholesterol acyltransferase [EC:2.3.1.43];K00680|1|0.0|842|dme:Dmel_CG18858| [EC:2.3.1.-];K06129|2|0.0|839|dme:Dmel_CG31683|lysophospholipase III [EC:3.1.1.5] - GO:0008374//O-acyltransferase activity GO:0044238//primary metabolic process 31126 898.00 1.315 1.18 -0.156275939930461 Down 0.0909721304979527 CG14798 CG14798 K10769|1|2e-42|145|dme:Dmel_CG14130|alkylated DNA repair protein alkB homolog 7 - - - 33715 1141.29 70.995 74.425 0.0680698936658787 Up 0.191057984414212 mRpL28 mitochondrial ribosomal protein L28, isoform B - GO:0000315//organellar large ribosomal subunit GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0005198//structural molecule activity GO:0010467//gene expression 38953 830.00 0.105 0.215 1.03394733192334 Up 0.112336547351737 Jon66Cii jonah 66Cii K01310|1|1e-86|319|dme:Dmel_CG31362|chymotrypsin [EC:3.4.21.1];K01362|2|1e-86|319|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31743 1836.00 2.27 2.865 0.33584284146599 Up 0.221172896579052 CG10959 CG10959, isoform B K09228|1|2e-51|203|cfa:474650|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 19835610 1023.00 0.41 0.44 0.101879614019213 Up 0.0512812045964866 319047 676.00 0.465 0.335 -0.473069620650259 Down 0.107647602694492 CG31960 CG31960 K02183|1|4e-38|157|bta:514457|calmodulin - GO:0046872//metal ion binding - 31779 925.60 6.81 12.21 0.842336496975332 Up 0.590740985338793 CG15347 CG15347, isoform B - - - - 42598 553.46 262.21 172.535 -0.603833654273153 Down 0.672929599788667 CG5778 CG5778, isoform C - - - - 33679 1432.00 21.98 25.935 0.238708983414207 Up 0.397305507858935 CG15629 CG15629 K11151|1|7e-44|178|cfa:486998|retinol dehydrogenase 10 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 40670 2985.46 22.05 25.02 0.182303133720937 Up 0.331693303394532 Pi4KIIalpha Pi4KIIalpha, isoform C K13711|1|0.0|1289|dme:Dmel_CG2929|phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67] - GO:0001727//lipid kinase activity;GO:0001727//lipid kinase activity;GO:0001727//lipid kinase activity GO:0030384;GO:0030384;GO:0030384 44279 6024.00 11.185 8.355 -0.420853522997931 Down 0.444888389908863 arr arrow K03068|1|0.0|3258|dme:Dmel_CG5912|low density lipoprotein receptor-related protein 5/6 GO:0031224//intrinsic to membrane - - 2768926 1779.00 0.32 0.52 0.700439718141092 Up 0.138521991810857 CG33309 CG33309 - - - - 36437 3441.39 2.09 3.035 0.5381935741748 Up 0.300719852067098 CG13325 CG13325, isoform D K00680|1|0.0|769|dme:Dmel_CG33337| [EC:2.3.1.-];K08252|2|2e-09|65.5|dme:Dmel_CG3915|receptor protein-tyrosine kinase [EC:2.7.10.1] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 41281 487.00 1.13 1.935 0.776010793729223 Up 0.298903711530841 CG14684 CG14684 - - - - 40961 1137.11 64.055 81.76 0.352084007540577 Up 0.551413287544578 Gie GTPase indispensable for equal segregation of chromosomes, isoform C K07977|1|6e-104|377|dme:Dmel_CG7891|Arf/Sar family, other;K07956|3|1e-94|345|dre:337424|ADP-ribosylation factor-like 8B GO:0005764//lysosome;GO:0005770//late endosome;GO:0044430//cytoskeletal part GO:0017111//nucleoside-triphosphatase activity;GO:0001883//purine nucleoside binding;GO:0032561//guanyl ribonucleotide binding;GO:0015631//tubulin binding GO:0035556//intracellular signal transduction;GO:0007059//chromosome segregation;GO:0000087//M phase of mitotic cell cycle 33018 1094.00 11.135 13.15 0.239961241391875 Up 0.335688812574297 CG9578 CG9578 - - - - 35613 912.35 33.93 17.135 -0.985615238191803 Down 0.687425703341699 Tsp42Ed tetraspanin 42Ed, isoform B K06497|1|5e-46|184|dan:Dana_GF13154|CD63 antigen GO:0031224//intrinsic to membrane - - 42091 1354.00 22.12 21.1 -0.0681083866401595 Down 0.16067890635319 sds22 sds22 K01768|1|5e-79|295|mcc:700574|adenylate cyclase [EC:4.6.1.1];K11293|3|2e-53|209|cbr:CBG03541|protein HIRA/HIR1 - - - 42889 4488.55 78.03 94.675 0.278954616107635 Up 0.496995112930921 jar jaguar, isoform N K10358|1|0.0|2376|dme:Dmel_CG5695|myosin VI GO:0005884//actin filament;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0005884//actin filament;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0005884//actin filament;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0005884//actin filament;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0005884//actin filament;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0005884//actin filament;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge GO:0003779//actin binding;GO:0032027//myosin light chain binding;GO:0032559;GO:0015631//tubulin binding;GO:0016887//ATPase activity;GO:0003779//actin binding;GO:0032027//myosin light chain binding;GO:0032559;GO:0015631//tubulin binding;GO:0016887//ATPase activity;GO:0003779//actin binding;GO:0032027//myosin light chain binding;GO:0032559;GO:0015631//tubulin binding;GO:0016887//ATPase activity;GO:0003779//actin binding;GO:0032027//myosin light chain binding;GO:0032559;GO:0015631//tubulin binding;GO:0016887//ATPase activity;GO:0003779//actin binding;GO:0032027//myosin light chain binding;GO:0032559;GO:0015631//tubulin binding;GO:0016887//ATPase activity;GO:0003779//actin binding;GO:0032027//myosin light chain binding;GO:0032559;GO:0015631//tubulin binding;GO:0016887//ATPase activity GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0007444//imaginal disc development;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0034331;GO:0002168//instar larval development;GO:0007303//cytoplasmic transport, nurse cell to oocyte;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048103//somatic stem cell division;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0007444//imaginal disc development;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0034331;GO:0002168//instar larval development;GO:0007303//cytoplasmic transport, nurse cell to oocyte;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048103//somatic stem cell division;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0007444//imaginal disc development;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0034331;GO:0002168//instar larval development;GO:0007303//cytoplasmic transport, nurse cell to oocyte;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048103//somatic stem cell division;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0007444//imaginal disc development;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0034331;GO:0002168//instar larval development;GO:0007303//cytoplasmic transport, nurse cell to oocyte;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048103//somatic stem cell division;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0007444//imaginal disc development;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0034331;GO:0002168//instar larval development;GO:0007303//cytoplasmic transport, nurse cell to oocyte;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048103//somatic stem cell division;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0007444//imaginal disc development;GO:0045165//cell fate commitment;GO:0007297//ovarian follicle cell migration;GO:0034331;GO:0002168//instar larval development;GO:0007303//cytoplasmic transport, nurse cell to oocyte;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048103//somatic stem cell division;GO:0007281//germ cell development;GO:0048232//male gamete generation 31996 1034.00 0.305 0.585 0.939627382020518 Up 0.177849689605072 CG12637 CG12637 - - - - 31705 1461.00 0.215 0.29 0.431716240425474 Up 0.0829150706643772 hdm hold'em - - - - 31394 2601.00 0.285 0.2 -0.510961919277379 Down 0.0930524369303923 pon partner of numb - GO:0044448//cell cortex part - GO:0045165//cell fate commitment 44783 514.32 688.44 748.925 0.121490325506869 Up 0.304649319772817 RpL37A ribosomal protein L37A, isoform C K02921|1|9e-39|159|dya:Dyak_GE11334|large subunit ribosomal protein L37Ae GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 43132 1532.00 9.98 9.92 -0.00869969495038533 Down 0.0502575617487782 CG5913 CG5913 - - - - 37961 3888.33 52.185 59.285 0.184031947637688 Up 0.371714436666226 Eps-15 epidermal growth factor receptor pathway substrate clone 15, isoform D K12472|1|5e-50|200|bta:535998|epidermal growth factor receptor substrate 15 GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0048638//regulation of developmental growth;GO:0008593//regulation of Notch signaling pathway;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0048638//regulation of developmental growth;GO:0008593//regulation of Notch signaling pathway;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0048638//regulation of developmental growth;GO:0008593//regulation of Notch signaling pathway;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis 38647 1711.00 13.81 16.325 0.241369672175742 Up 0.359232598071589 Ppat-Dpck bifunctional phosphopantetheine adenylyltransferase - Dephospho-CoA kinase K02318|1|0.0|923|dme:Dmel_CG10575|phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24] GO:0044424//intracellular part GO:0016301//kinase activity;GO:0032559 GO:0009108//coenzyme biosynthetic process 39802 539.00 1.19 0.84 -0.502500340529183 Down 0.17864218729362 CG13060 CG13060 - - - - 33504 763.00 13.115 13.765 0.069786802330577 Up 0.141361775194822 CG9643 CG9643, isoform B K01415|1|8e-07|54.3|mmu:107522|endothelin-converting enzyme [EC:3.4.24.71] - GO:0016741 - 32038 624.00 29.89 44.95 0.588658218723715 Up 0.63125742966583 CG15203 CG15203, isoform B - - - - 39905 2244.00 1.195 1.765 0.562657565290432 Up 0.234678378021397 CG6652 CG6652 - - - - 41122 1519.00 12.87 13.08 0.0233504872773808 Up 0.0702351076476027 CG9356 CG9356, isoform B - - - - 5740830 265.00 2.12 5.675 1.42055612761508 Up 0.578886540747589 14462868 382.00 0.45 0.01 -5.49185309632967 Down 0.339420155857879 34735 2514.28 13.185 13.21 0.00273289538226769 Up 0.0427618544445912 Uvrag UV-resistance associated gene, isoform B - - - - 10178946 468.00 1.19 0.44 -1.43538614467065 Down 0.320334169858671 CG42792 CG42792, isoform B - - - - 317855 4534.27 0.25 0.575 1.20163386116965 Up 0.199115044247788 CG32106 CG32106, isoform E - - - - 19835293 652.00 0.695 2.4 1.78794952288501 Up 0.471833311319509 38964 1692.19 126.09 184.465 0.548893246013634 Up 0.656386210540219 CG6983 CG6983, isoform B - - - - 19835642 521.00 0.945 0.79 -0.25846167604397 Down 0.101340641923128 - CG45603 - - - - 319014 1884.00 0.96 0.27 -1.83007499855769 Down 0.318220842689209 Mur29B mucin related 29B - - - - 36237 1260.34 23.59 13.71 -0.782946847460236 Down 0.63924844802536 CG7777 CG7777, isoform D K09884|1|8e-137|486|dsi:Dsim_GD10798|aquaporin rerated protein, invertebrate GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0022803;GO:0022803 GO:0006810//transport;GO:0006810//transport 45883 2203.98 41.77 33.695 -0.309932617683532 Down 0.494716682076344 kar karmoisin, isoform B K08187|1|0.0|993|dme:Dmel_CG12286|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10 GO:0016020//membrane;GO:0016020//membrane GO:0046943//carboxylic acid transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0006810//transport;GO:0006810//transport 38539 3860.06 84.45 107.785 0.351987089920058 Up 0.558578787478537 DopEcR Dopamine/Ecdysteroid receptor, isoform C K04141|1|4e-25|117|dre:557194|adrenergic receptor beta-1;K04142|2|5e-25|116|mmu:11555|adrenergic receptor beta-2;K08407|5|6e-25|116|mmu:620246|G protein-coupled receptor 52 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0016740//transferase activity;GO:0004930//G-protein coupled receptor activity;GO:0016740//transferase activity;GO:0004930//G-protein coupled receptor activity;GO:0016740//transferase activity GO:0007166//cell surface receptor signaling pathway;GO:0002165//instar larval or pupal development;GO:0007166//cell surface receptor signaling pathway;GO:0002165//instar larval or pupal development;GO:0007166//cell surface receptor signaling pathway;GO:0002165//instar larval or pupal development 42645 1253.00 13.6 14.27 0.0693786833380618 Up 0.142649583938714 CG5377 CG5377 K01175|1|5e-64|244|hsa:670| [EC:3.1.-.-] - - - 42701 2213.00 33.37 40.96 0.295664028817681 Up 0.485437854972923 CG4721 CG4721 K01415|1|4e-75|283|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|9e-44|178|dmo:Dmoj_GI16188|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 44007 899.00 41.25 49.065 0.250300140783394 Up 0.444029850746269 COQ7 COQ7 K06134|1|4e-105|380|dme:Dmel_CG14437|ubiquinone biosynthesis monooxygenase Coq7 [EC:1.14.13.-] - GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0006743//ubiquinone metabolic process;GO:0043170 2768848 4101.14 5.75 6.2 0.1087062594425 Up 0.142484480253599 mute muscle wasted, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 35535 2692.80 2.64 2.83 0.100264123473429 Up 0.0928543125082552 CCHa2r CCHamide-2 receptor, isoform B K04169|1|3e-44|180|tgu:100232773|gastrin-releasing peptide receptor;K04170|2|5e-44|179|oaa:100083667|bombesin-like receptor 3;K04168|3|1e-43|178|gga:428610|neuromedin B receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway 39784 450.00 3.44 1.785 -0.946484490672998 Down 0.426726984546295 CG13068 CG13068 - - - - 41580 1095.00 0.32 0.24 -0.415037499278844 Down 0.0875709945845991 d-cup davis-cup - - - - 33234 1584.00 5.81 7.05 0.279085093881627 Up 0.296162990357945 Nle notchless K04508|1|1e-35|150|dpe:Dper_GL13421|transducin (beta)-like 1;K01062|5|2e-33|143|cqu:CpipJ_CPIJ001448|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - GO:0008415;GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway 37478 703.99 47.985 56.405 0.233239562276934 Up 0.430161141196672 Tim10 translocase of inner membrane 10, isoform B - GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity;GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane;GO:0006612//protein targeting to membrane 43625 1737.00 0.45 1.65 1.87446911791614 Up 0.412098798045172 PH4alphaNE1 prolyl-4-hydroxylase-alpha NE1 K00472|1|0.0|1073|dme:Dmel_CG9728|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 14462880 601.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 19835207 1065.00 0.34 0.325 -0.065095028221885 Down 0.045898824461762 - CG45095 - - - - 43831 687.00 40.495 47.385 0.226686651302935 Up 0.421872936203936 CG11077 CG11077 K13348|1|4e-94|343|dme:Dmel_CG11077|protein Mpv17 - - - 246453 645.00 0.325 0.01 -5.02236781302845 Down 0.285233126403381 CG30095 CG30095 - - GO:0003824//catalytic activity - 38350 1996.00 16.425 6.8 -1.27228671907199 Down 0.677354378549729 spz5 spatzle 5 - - GO:0005102//receptor binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0007411//axon guidance 19835169 449.00 32.21 53.535 0.732973741387364 Up 0.670684189671113 3772641 1753.69 7.935 10.785 0.442724048325272 Up 0.451129309206181 Shawn shawn, isoform E K03454|1|6e-20|100|dre:406393|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 41656 3932.88 13.7 12.94 -0.0823382758553815 Down 0.157409853387928 yrt yurt, isoform D K06107|1|4e-71|270|mdo:100024567|erythrocyte membrane protein band 4.1 GO:0043296//apical junction complex;GO:0005913//cell-cell adherens junction;GO:0044424//intracellular part;GO:0043296//apical junction complex;GO:0005913//cell-cell adherens junction;GO:0043232;GO:0043296//apical junction complex;GO:0005913//cell-cell adherens junction;GO:0043232 GO:0005488//binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0001894//tissue homeostasis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0001754//eye photoreceptor cell differentiation;GO:0001894//tissue homeostasis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0001754//eye photoreceptor cell differentiation;GO:0001894//tissue homeostasis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0001754//eye photoreceptor cell differentiation 43601 1465.18 18.385 5.025 -1.87133367513701 Down 0.724838198388588 CG9733 CG9733, isoform B K01312|1|5e-85|315|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|3e-60|232|dme:Dmel_CG4920| [EC:3.4.21.-];K09626|5|9e-34|144|rno:302971|protease, serine, 22 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32489 1559.58 5.17 7.335 0.504632685358455 Up 0.422830537577599 CG15643 CG15643, isoform B - - - - 19835102 497.00 0.255 0.5 0.971430847803229 Up 0.162561088363492 19836070 904.00 11.885 13.33 0.165534877146538 Up 0.266576409985471 326119 1921.80 28.235 30.09 0.0917994753520475 Up 0.2073702285035 5PtaseI 5PtaseI, isoform F K01106|1|1e-151|537|aga:AgaP_AGAP000203|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] - GO:0046030//inositol trisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0019904//protein domain specific binding GO:0006020//inositol metabolic process;GO:0006020//inositol metabolic process;GO:0006020//inositol metabolic process 318725 1323.00 0.175 0.18 0.0406419844973458 Up 0.0382380134724607 Takl1 Tak1-like 1 K04427|1|7e-57|221|dvi:Dvir_GJ19194|mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] - GO:0032559;GO:0004709//MAP kinase kinase kinase activity GO:0000186//activation of MAPKK activity;GO:0012501//programmed cell death;GO:0007389//pattern specification process;GO:0009886//post-embryonic morphogenesis;GO:0002252;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0002780 31186 748.00 18.025 32.865 0.866552725583194 Up 0.671377625148593 bcn92 bcn92 - - - - 246608 977.49 19.45 17.46 -0.155716596244114 Down 0.285629375247656 CG30428 CG30428, isoform B - - - - 36325 415.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 CG13170 CG13170 - - - - 37386 6400.00 15.96 16.565 0.0536775518586683 Up 0.121879540351341 shg shotgun K10414|1|8e-125|449|dmo:Dmoj_GI22290|dynein heavy chain 2, cytosolic - - - 48317 4360.53 23.035 26.11 0.180774859708631 Up 0.333542464667811 ttk tramtrack, isoform H K09237|1|0.0|1048|dme:Dmel_CG1856|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007424//open tracheal system development;GO:0060560//developmental growth involved in morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035150//regulation of tube size;GO:0002118//aggressive behavior;GO:0035146;GO:0042335//cuticle development;GO:0042051//compound eye photoreceptor development 38538 965.00 2.505 2.45 -0.0320288541926377 Down 0.0530643243957205 CG11342 CG11342 - - GO:0016741 - 40874 663.00 0.825 0.845 0.0345572220363684 Up 0.0445449742438251 Obp84a Odorant-binding protein 84a, isoform C - - GO:0008144//drug binding;GO:0005549//odorant binding;GO:0008144//drug binding;GO:0005549//odorant binding GO:0051234//establishment of localization;GO:0051234//establishment of localization 12798253 588.00 0.14 0.31 1.14684138832927 Up 0.141196671509708 CG43246 CG43246 - - - - 7354386 1356.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 326164 1036.00 4.18 3.44 -0.281094377378785 Down 0.232961299696209 CG31826 CG31826, isoform C - GO:0044464//cell part - GO:0051234//establishment of localization 36824 4017.00 4.635 4.935 0.0904807458308671 Up 0.111180821555937 CG8060 CG8060 K10615|1|2e-13|79.0|aga:AgaP_AGAP006994|E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19];K11494|2|2e-11|72.4|dre:336007|RCC1 and BTB domain-containing protein - GO:0005488//binding - 35798 819.00 0.195 0.265 0.442518235700951 Up 0.0830471536124686 CG14756 CG14756 - - - - 326149 1950.00 1.015 1.09 0.10284840759175 Up 0.0638951261392154 CG31642 CG31642 - - GO:0046914//transition metal ion binding - 38919 489.00 0.615 0.395 -0.638733757162137 Down 0.143309998679171 CG13679 CG13679 - - - - 19835655 1397.00 0.575 0.49 -0.230780206829167 Down 0.077895918636904 - CG44403 - - - - 35060 1526.00 44.215 50.94 0.204263070664496 Up 0.392583542464668 CG6412 CG6412 K02357|1|0.0|653|dme:Dmel_CG6412|elongation factor EF-Ts GO:0043231//intracellular membrane-bounded organelle GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 19836023 353.00 0.01 0.17 4.08746284125034 Up 0.187062475234447 39388 2039.00 4.255 5.695 0.420536710022149 Up 0.348434817065117 CG9760 CG9760, isoform D - - - - 31553 1801.00 41.91 32.98 -0.345703122693152 Down 0.524765552767138 Efr ER GDP-fucose transporter, isoform B - - - - 19835757 328.00 0.15 0.51 1.76553474636298 Up 0.227248712191256 31178 1936.00 16.17 15.18 -0.0911478880581954 Down 0.178840311715757 CG16903 CG16903 - - - - 30972 1547.70 42.71 31.36 -0.445648338526934 Down 0.579877162858275 CG13377 CG13377, isoform B K00019|1|0.0|637|dme:Dmel_CG13377|3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] - - - 35953 2031.76 10.545 11.075 0.0707476036486892 Up 0.131686699247127 CG1968 CG1968, isoform B - - - - 36894 794.00 62.885 38.88 -0.693687712209192 Down 0.666028265750892 CG6435 CG6435 - - - - 38248 3658.90 10.135 9.815 -0.0462859160007281 Down 0.0997556465460309 dre4 dre4, isoform B - GO:0008023//transcription elongation factor complex;GO:0008023//transcription elongation factor complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006333//chromatin assembly or disassembly;GO:0006333//chromatin assembly or disassembly 34087 2945.84 22.355 20.21 -0.145528224162906 Down 0.282525425967508 pes peste, isoform H K12384|1|3e-52|207|cfa:478435|lysosome membrane protein 2;K13885|2|1e-50|201|mdo:100029588|scavenger receptor class B, member 1 GO:0016021//integral to membrane;GO:0016021//integral to membrane - GO:0006950//response to stress;GO:0009987//cellular process;GO:0006950//response to stress;GO:0009987//cellular process 43532 737.86 1187.07 1158.105 -0.0356389496560761 Down 0.140470215295205 RpS8 ribosomal protein S8, isoform G K02995|1|5e-105|380|dsi:Dsim_GD21475|small subunit ribosomal protein S8e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 4379919 2458.90 117.255 123.835 0.0787696834672618 Up 0.215559371285167 CG17698 CG17698, isoform F K07359|1|0.0|739|dme:Dmel_CG17698|calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17] - GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 39791 781.00 4.1 1.115 -1.87858019958514 Down 0.571291771232334 CG13046 CG13046 - - - - 14462452 935.00 4.225 5.44 0.364655310080793 Up 0.313763043191124 CG12256 CG12256 K11997|1|9e-33|140|ame:409206|tripartite motif-containing protein 2/3;K01312|2|1e-28|127|dpo:Dpse_GA11599|trypsin [EC:3.4.21.4];K01362|3|9e-28|124|dme:Dmel_CG2071| [EC:3.4.21.-];K01324|4|1e-26|120|bta:533547|plasma kallikrein [EC:3.4.21.34];K09628|5|1e-26|120|mcc:697848|protease, serine 27 [EC:3.4.21.-] - - - 39043 4775.00 31.82 33.58 0.0776683946059824 Up 0.191883502839783 CG4911 CG4911, isoform C K10310|1|0.0|914|dme:Dmel_CG4911|F-box protein 33 - - - 37864 4088.90 15.76 16.425 0.0596258357533159 Up 0.135352001056664 tamo tamo, isoform C - GO:0044424//intracellular part;GO:0044424//intracellular part GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0005048//signal sequence binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0005048//signal sequence binding GO:0032501//multicellular organismal process;GO:0006810//transport;GO:0032501//multicellular organismal process;GO:0006810//transport 42486 813.00 0.595 0.645 0.116409492115311 Up 0.0607251353850218 CG12278 CG12278 - - - - 33422 929.00 3.715 5.265 0.503071320487121 Up 0.371021001188747 CG15390 CG15390 - - - - 39152 804.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 Ilp4 Insulin-like peptide 4 - - GO:0005102//receptor binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030537//larval behavior 34620 3980.00 0.73 0.945 0.372417865341056 Up 0.13010170387003 CG6785 CG6785, isoform C - - - - 33547 1595.00 0.22 0.225 0.0324214776923774 Up 0.0416391493858143 CG3285 CG3285, isoform B K08145|1|4e-42|172|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane - GO:0006810//transport 5740860 1059.00 0.525 0.305 -0.783508180103236 Down 0.149881125346718 CG34251 CG34251, isoform B - - - - 10178970 623.00 0.195 0.075 -1.37851162325373 Down 0.120525690133404 14462898 486.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 38632 1749.00 1.105 0.34 -1.70043971814109 Down 0.331164971602166 CG10592 CG10592 K01077|1|0.0|1058|dme:Dmel_CG10592|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 43488 574.61 14.26 5.01 -1.50909147324868 Down 0.687392682604676 Obp99a Odorant-binding protein 99a, isoform B - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization;GO:0010033//response to organic substance;GO:0007635//chemosensory behavior 33808 1396.00 5.23 5.475 0.0660480182415941 Up 0.0944062871483291 CG14005 CG14005, isoform B - - - - 39556 1976.00 1.145 1.785 0.640576475932156 Up 0.254127592127856 CG6661 CG6661 K00294|1|0.0|1100|dme:Dmel_CG6661|1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.1.12] GO:0031980 GO:0003824//catalytic activity GO:0009064//glutamine family amino acid metabolic process 42401 1591.00 0.24 0.4 0.736965594166206 Up 0.126634526482631 CG17199 CG17199 - - GO:0003824//catalytic activity GO:0008152//metabolic process 32671 2190.00 0.765 0.43 -0.831123087990554 Down 0.192048606524898 ppk28 pickpocket 28 K04832|1|7e-84|311|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|2|1e-16|88.6|dre:407670|amiloride-sensitive cation channel 2, neuronal;K04831|3|1e-16|88.2|dre:407668|amiloride-sensitive cation channel 4, pituitary GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0007631//feeding behavior;GO:0009415//response to water stimulus;GO:0030001//metal ion transport 34962 1489.45 3.83 5.145 0.425826684969011 Up 0.336679434684982 CG17328 CG17328, isoform B K09228|1|4e-37|155|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 44154 2008.79 31.13 36.135 0.215091317490447 Up 0.397569673755118 Hmgs HMG coenzyme A synthase, isoform F K01641|1|0.0|923|dme:Dmel_CG4311|hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] - GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0006694//steroid biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006720//isoprenoid metabolic process 19835142 2171.00 0.06 0.12 1 Up 0.0856557918372738 36537 1145.00 6.995 3 -1.22136155666887 Down 0.58317923656056 CG6553 CG6553 K06233|1|8e-16|84.7|hsa:4036|low density lipoprotein-related protein 2 - - - 39443 5166.33 9.635 9.68 0.00672238097887319 Up 0.0472856954167217 Ptp69D protein tyrosine phosphatase 69D, isoform B K01104|1|0.0|2908|dme:Dmel_CG10975|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043005//neuron projection;GO:0016020//membrane;GO:0043005//neuron projection;GO:0016020//membrane GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0007411//axon guidance;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0007414//axonal defasciculation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 40154 1409.00 1.215 1.995 0.715432432616565 Up 0.289195614846123 CG14101 male sterile (3) 76Ca - - - - 42758 6849.00 0.865 0.78 -0.149226008774476 Down 0.0742636375643904 DNApol-epsilon DNA polymerase epsilon K02324|1|0.0|4247|dme:Dmel_CG6768|DNA polymerase epsilon subunit 1 [EC:2.7.7.7] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0034061 GO:0006259//DNA metabolic process 42591 1382.13 224.83 245.38 0.126183111961114 Up 0.319145423325849 ND42 NADH:ubiquinone reductase 42kD subunit precursor, isoform C K03954|1|0.0|797|dme:Dmel_CG6343|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10 [EC:1.6.5.3 1.6.99.3] GO:0031980;GO:0005746//mitochondrial respiratory chain;GO:0031980;GO:0005746//mitochondrial respiratory chain GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0032559;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0032559 GO:0034641//cellular nitrogen compound metabolic process;GO:0022904//respiratory electron transport chain;GO:0034641//cellular nitrogen compound metabolic process;GO:0022904//respiratory electron transport chain 32972 2756.10 4.97 3.21 -0.630672554439983 Down 0.407112666754722 CG14223 CG14223, isoform C - - - - 34683 1020.00 78.56 75.055 -0.0658467454158876 Down 0.191190067362304 CG6180 CG6180 - - - - 12798461 732.00 0.33 0.845 1.35648531692373 Up 0.262184651961432 CG43329 CG43329 - - - - 39381 1637.00 14.415 11.43 -0.334745433280428 Down 0.425406155065381 CG11534 CG11534 K00901|1|1e-07|58.5|dya:Dyak_GE23434|diacylglycerol kinase [EC:2.7.1.107] - GO:0046914//transition metal ion binding GO:0023033 41748 1037.00 2.42 2.575 0.089565384795986 Up 0.0813300752872804 soti scotti - - - - 43635 1445.00 2.74 1.855 -0.562756706339723 Down 0.293422269185048 Rpt6R regulatory particle triple-A ATPase 6-related K03066|1|0.0|750|dme:Dmel_CG2241|26S proteasome regulatory subunit T6 GO:0005838//proteasome regulatory particle;GO:0015630//microtubule cytoskeleton GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 318722 720.00 1.11 2.085 0.909487707094558 Up 0.336151102892617 CG31415 CG31415 - - - - 32000 3018.60 9.245 10.475 0.180205019182518 Up 0.257231541408004 BTBD9 BTB (POZ) domain containing 9 ortholog, isoform B K10481|1|0.0|1215|dme:Dmel_CG1826|BTB/POZ domain-containing protein 9 - GO:0005488//binding GO:0009987//cellular process 34105 1404.00 1.695 2.82 0.73440988926245 Up 0.344307224937261 CG8673 CG8673 K07819|1|8e-91|334|dpe:Dper_GL24766|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-];K03877|5|2e-34|147|mcc:715466|beta-1,3-galactosyltransferase 5 [EC:2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process 32178 777.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 CG11356 CG11356 K07961|1|7e-11|67.4|ptr:465755|ADP-ribosylation factor-like 13;K07962|3|1e-09|63.5|cin:100178782|ADP-ribosylation factor-like 2-like 1 - GO:0032561//guanyl ribonucleotide binding - 12797971 341.00 2.155 5.47 1.34385296370346 Up 0.565215955620129 47954 325.00 38.885 37.99 -0.0335940267816739 Down 0.105171047417778 Mst57Da Male-specific RNA 57Da - - - - 19835750 410.00 1.435 1.89 0.397335497545385 Up 0.198553691718399 - CG44296 - - - - 3772545 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 12798579 677.00 0.24 0.01 -4.58496250072116 Down 0.234975564654603 CG43074 CG43074 - - - - 41825 4584.21 8.38 10.08 0.266473489800565 Up 0.330504556861709 Gyc88E guanylyl cyclase at 88E, isoform F K12319|1|5e-146|519|smm:Smp_149980|guanylate cyclase soluble subunit beta [EC:4.6.1.2] - - - 19836102 971.98 18.345 3.52 -2.38173957061125 Down 0.749438647470612 3771947 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33883 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 39426 1377.00 9.565 8.855 -0.111272661594198 Down 0.17319376568485 CG10646 CG10646 K10752|1|2e-06|53.9|cbr:CBG03711|histone-binding protein RBBP4 - - - 41742 654.00 44.06 64.26 0.544451485770529 Up 0.63148857482499 Crz corazonin - - - - 43435 11882.15 11.045 12.765 0.208800119051844 Up 0.30445119535068 CG11873 CG11873, isoform D - - - - 8673988 1169.16 11.52 11.33 -0.0239928556217966 Down 0.0688152159556201 CG42455 CG42455, isoform C K00670|1|2e-98|359|dsi:Dsim_GD14230|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 41153 2055.00 10.27 12.025 0.227600712339209 Up 0.316966054682341 Vps45 vacuolar protein sorting 45 K12479|1|0.0|1102|dme:Dmel_CG8228|vacuolar protein sorting-associated protein 45 GO:0030136//clathrin-coated vesicle GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0006906//vesicle fusion;GO:0048278//vesicle docking;GO:0007033//vacuole organization;GO:0015031//protein transport 326123 1666.00 2.05 2.79 0.444641212323742 Up 0.257957997622507 CG31161 CG31161 K02355|1|2e-149|529|dsi:Dsim_GD20968|elongation factor EF-G [EC:3.6.5.3];K06267|2|2e-06|53.9|hsa:3161|hyaluronan-mediated motility receptor - GO:0017111//nucleoside-triphosphatase activity;GO:0046914//transition metal ion binding;GO:0032561//guanyl ribonucleotide binding GO:0023060 14462906 634.00 0.195 0.01 -4.28540221886225 Down 0.201558578787479 35044 1683.00 15.605 16.24 0.0575432752659661 Up 0.133998150838727 CG15141 CG15141 K11979|1|0.0|817|dme:Dmel_CG15141|E3 ubiquitin-protein ligase UBR7 - GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding - 32668 942.00 32.69 33.98 0.0558364754169548 Up 0.157640998547088 CG4789 CG4789 K07933|1|2e-147|521|dme:Dmel_CG4789|Rab-like protein 3 - GO:0032561//guanyl ribonucleotide binding GO:0009987//cellular process 33968 5529.24 90.305 88.29 -0.0325558259414782 Down 0.111610091137234 Hrb27C heterogeneous nuclear ribonucleoprotein at 27C, isoform H K13044|1|1e-39|165|mdo:100032003|heterogeneous nuclear ribonucleoprotein A/B/D GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding GO:0017148//negative regulation of translation;GO:0043484//regulation of RNA splicing;GO:0007297//ovarian follicle cell migration;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006935//chemotaxis;GO:0017148//negative regulation of translation;GO:0043484//regulation of RNA splicing;GO:0007297//ovarian follicle cell migration;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006935//chemotaxis;GO:0017148//negative regulation of translation;GO:0043484//regulation of RNA splicing;GO:0007297//ovarian follicle cell migration;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006935//chemotaxis;GO:0017148//negative regulation of translation;GO:0043484//regulation of RNA splicing;GO:0007297//ovarian follicle cell migration;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006935//chemotaxis;GO:0017148//negative regulation of translation;GO:0043484//regulation of RNA splicing;GO:0007297//ovarian follicle cell migration;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0006935//chemotaxis 12798486 261.00 0.88 1.6 0.862496476250065 Up 0.287445515783912 CG43176 CG43176 - - - - 12798550 532.00 1.835 1.46 -0.329811693963196 Down 0.174019284110421 CG43165 CG43165 - - - - 33356 1436.00 12.19 12.42 0.0269670476002694 Up 0.0789195614846123 CG17712 CG17712 - - GO:0003824//catalytic activity GO:0008152//metabolic process 33452 1147.00 0.24 0.265 0.142957953842043 Up 0.0546823405098402 CG9879 CG9879 K03120|1|2e-07|56.6|cqu:CpipJ_CPIJ001883|transcription initiation factor TFIID TATA-box-binding protein - GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0006352//DNA-dependent transcription, initiation 326142 1342.00 4.895 4.855 -0.0118375641845025 Down 0.0472856954167217 CG31457 CG31457 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 42882 3490.00 4.305 4.425 0.0396642175735158 Up 0.0677255316338661 Spps Sp1-like factor for pairing sensitive-silencing, isoform B K09200|1|0.0|1162|dme:Dmel_CG5669|transcription factor Sp, invertebrate - GO:0005488//binding - 33103 6321.54 19.985 23.055 0.206162092991481 Up 0.357845727116629 CG1718 CG1718, isoform D K05643|1|0.0|1070|bta:505787|ATP-binding cassette, subfamily A (ABC1), member 3 GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 35067 863.04 131.84 185.87 0.495505785916411 Up 0.638918240655131 CG6870 CG6870, isoform B K10595|1|2e-10|65.9|tad:TRIADDRAFT_56425|E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19];K10224|2|6e-10|64.7|hsa:3992|fatty acid desaturase 1 (delta-5 desaturase) [EC:1.14.19.-];K10226|3|7e-10|64.3|cfa:483792|fatty acid desaturase 2 (delta-6 desaturase) [EC:1.14.19.-] - GO:0005506//iron ion binding - 43723 966.92 752.64 742.49 -0.0195883697405969 Down 0.093778893144895 RpL6 ribosomal protein L6, isoform B K02934|1|9e-116|416|dse:Dsec_GM16427|large subunit ribosomal protein L6e GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 32518 1924.00 33.3 31.35 -0.087056734269223 Down 0.208922203143574 Tcp-1zeta T-cp1zeta K09498|1|0.0|944|dme:Dmel_CG8231|T-complex protein 1 subunit zeta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0000226//microtubule cytoskeleton organization 32281 1403.32 16.295 19.4 0.251627300335926 Up 0.384625544842161 CG1764 CG1764, isoform B K01482|1|1e-150|532|dme:Dmel_CG1764|dimethylargininase [EC:3.5.3.18] GO:0044424//intracellular part GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - 37302 3374.88 117.885 117.11 -0.00951588510664317 Down 0.068187821952186 CG13868 CG13868, isoform B - - - - 3772088 505.00 0.25 0.095 -1.39592867633114 Down 0.140173028662 41845 802.00 657.79 620.97 -0.083103504534123 Down 0.225597675340114 Oscp oligomycin sensitivity-conferring protein K02137|1|1e-100|365|dme:Dmel_CG4307|F-type H+-transporting ATPase oligomycin sensitivity conferral protein [EC:3.6.3.14] - - - 37926 2059.93 12.255 11.67 -0.0705659231594914 Down 0.135616166952846 CG3511 CG3511, isoform B K12736|1|0.0|1201|dme:Dmel_CG3511|peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8] - GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 40604 449.00 0.01 0.21 4.39231742277876 Up 0.216153744551578 CG14659 CG14659 - - - - 32507 1448.45 20.165 18.315 -0.138827704697317 Down 0.264000792497689 CG8134 CG8134, isoform B - - - - 37836 1239.00 8.38 9.065 0.113356776044806 Up 0.170056795667679 CG3163 CG3163 - - - - 36373 2132.00 3.76 4.8 0.352301743930881 Up 0.289922071060626 achi achintya, isoform D K11649|1|6e-12|73.2|tgu:100229325|SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C;K09355|2|6e-07|56.6|nve:NEMVE_v1g229018|pre-B-cell leukemia transcription factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010468//regulation of gene expression;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process 35396 2214.26 46.49 39.83 -0.223064946154778 Down 0.411273279619601 CG8678 Autophagy-specific gene 18b, isoform B - - - - 36188 829.00 21.28 13.04 -0.706554281270112 Down 0.615374455157839 Cpr47Ea cuticular protein 47Ea - - GO:0005198//structural molecule activity - 39854 1154.00 9.105 12.195 0.421558835819346 Up 0.456808875974112 CG4098 CG4098 K13988|1|3e-163|574|dme:Dmel_CG4098|ADP-ribose pyrophosphatase [EC:3.6.1.13] - GO:0003824//catalytic activity - 43730 5861.84 10.74 11.82 0.13823604219212 Up 0.223385285959583 CG1815 CG1815, isoform C K08883|1|3e-06|55.8|mmu:94093|tripartite motif-containing protein 33 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 35155 2859.00 5.84 7.585 0.377180811367016 Up 0.36966715097081 Tango6 transport and golgi organization 6 - GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization 40723 2311.00 8.86 8.925 0.010545470361444 Up 0.0513802668075551 Hpr1 Hpr1 K12878|1|0.0|1340|dme:Dmel_CG2031|THO complex subunit 1 - GO:0005488//binding GO:0006405//RNA export from nucleus;GO:0023060 35176 1692.00 103.37 54.385 -0.92653684822864 Down 0.714931977281733 Rpn3 regulatory particle non-ATPase 3, isoform B K03033|1|0.0|897|dme:Dmel_CG42641|26S proteasome regulatory subunit N3 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0009894 35879 377.00 42.72 41.67 -0.0359025469850051 Down 0.123860784572712 CG13751 CG13751 - - - - 41484 953.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 CG3916 CG3916 K11997|1|3e-30|132|ame:409206|tripartite motif-containing protein 2/3;K09632|2|5e-26|117|gga:427531|chymotrypsin-like protease [EC:3.4.21.-];K01312|3|7e-26|117|dpo:Dpse_GA15051|trypsin [EC:3.4.21.4];K01310|4|1e-25|116|bta:618826|chymotrypsin [EC:3.4.21.1];K01324|5|2e-24|112|bta:533547|plasma kallikrein [EC:3.4.21.34] - - - 35654 2614.33 16.58 18.185 0.133304918959866 Up 0.245509179764892 CG11107 CG11107, isoform B K12820|1|0.0|1398|dme:Dmel_CG11107|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:3.6.4.13] GO:0005681//spliceosomal complex GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377 31864 1252.00 0.065 0.115 0.823122237915921 Up 0.07657508915599 CG15370 CG15370 - - - - 8674104 1468.00 6.705 11.59 0.789571329101998 Up 0.575287280412099 CG42568 CG42568, isoform B K09524|1|2e-09|64.3|hsa:3338|DnaJ homolog subfamily C member 4;K09504|4|3e-08|60.1|gga:416671|DnaJ homolog subfamily A member 3 - GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation;GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation 40772 840.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 CG31560 CG31560 - - - - 12798153 932.00 0.6 0.955 0.67053823242723 Up 0.188812574296658 33077 2132.61 5.04 4.815 -0.0658879356564573 Down 0.0926231673490952 CG1529 CG1529, isoform D K09228|1|2e-21|105|rno:308232|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 36770 1053.00 8.32 12.55 0.593031930697042 Up 0.530643243957205 CG8401 CG8401 - - - - 7354434 8008.72 13.91 15.68 0.172803139572969 Up 0.284539690925901 CG42265 CG42265, isoform E - - - - 33325 755.00 0.565 0.935 0.726715497472449 Up 0.196110157178708 CG14346 CG14346, isoform D - - - - 43737 704.00 31.045 26.12 -0.249206034812237 Down 0.419693567560428 CG1890 CG1890 - GO:0015630//microtubule cytoskeleton GO:0005515//protein binding GO:0043623//cellular protein complex assembly 31797 1573.35 8.115 7.705 -0.0747961380331862 Down 0.11943600581165 spirit serine protease immune response integrator, isoform D K01312|1|1e-40|167|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4];K01324|2|4e-30|132|xla:446603|plasma kallikrein [EC:3.4.21.34];K01323|3|6e-30|132|mmu:109821|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway;GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway;GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway 3885632 551.00 1.105 1.005 -0.136850868212503 Down 0.078325188218201 CG34012 CG34012 - - - - 31245 2045.00 5.83 4.37 -0.415862603699898 Down 0.350383040549465 Seipin seipin - - - - 40981 1225.00 4.72 5.15 0.12578557270874 Up 0.146942279751684 Gfr neuronally altered carbohydrate - GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity GO:0015781//pyrimidine nucleotide-sugar transport;GO:0016192//vesicle-mediated transport;GO:0001654//eye development 19836214 860.00 9.32 9.895 0.0863697523932317 Up 0.147668735966187 37567 3656.08 23.25 28.58 0.29777520021306 Up 0.463214898956545 CG10384 CG10384, isoform E K13198|1|5e-33|142|gga:374071|KH domain-containing, RNA-binding, signal transduction-associated protein 1 - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 39543 4062.04 21.95 24.51 0.159149544444119 Up 0.303823801347246 CG17364 CG17364, isoform F - - - - 43950 2391.35 284.79 492.84 0.791220864162804 Up 0.712917712323339 CdsA CDP diglyceride synthetase, isoform B K00981|1|0.0|866|dme:Dmel_CG7962|phosphatidate cytidylyltransferase [EC:2.7.7.41] GO:0016021//integral to membrane;GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum GO:0070567 GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007165//signal transduction;GO:0060446//branching involved in open tracheal system development 19834867 515.00 0.165 0.195 0.241008099503795 Up 0.0577532690529653 39347 975.00 0.64 1.07 0.741466986401147 Up 0.213875313697002 CG11588 CG11588, isoform B - - - - 7354412 1782.00 0.305 0.32 0.0692626624371138 Up 0.045898824461762 Ir94d ionotropic receptor 94d - - - - 38505 9902.23 13.535 17.105 0.337723216552936 Up 0.448718795403513 CG43367 CG43367, isoform F - - - - 43246 2127.00 0.01 0.14 3.8073549220576 Up 0.163848897107383 CG6296 CG6296 K01046|1|2e-86|320|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|1|2e-86|320|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32];K01059|2|8e-35|149|dpo:Dpse_GA18274|lipoprotein lipase [EC:3.1.1.34] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 49080 830.00 10.39 6.73 -0.626517244293895 Down 0.517864218729362 epsilonTry epsilonTrypsin K01312|1|6e-132|469|dme:Dmel_CG18681|trypsin [EC:3.4.21.4] GO:0044421//extracellular region part GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35289 1310.00 5.1 6.04 0.244051302466221 Up 0.247985735041606 vls valois K06676|1|1e-98|360|dsi:Dsim_GD21719|condensin complex subunit 2;K13221|2|2e-31|136|cqu:CpipJ_CPIJ010038|methylosome protein 50 GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0005737//cytoplasm - GO:0051276//chromosome organization;GO:0000087//M phase of mitotic cell cycle;GO:0007028//cytoplasm organization;GO:0009790//embryo development 44793 1794.00 3.645 4.03 0.14486102420103 Up 0.143640206049399 abo abnormal oocyte K10571|1|0.0|1065|dme:Dmel_CG6093|de-etiolated-1 GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome GO:0005488//binding GO:0006357//regulation of transcription from RNA polymerase II promoter 19835597 1122.00 0.135 0.045 -1.58496250072116 Down 0.107218333113195 - CG45072 - - - - 12798139 679.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 42920 2197.62 39.905 47.88 0.262853628308228 Up 0.453704926693964 nAcRbeta-96A nicotinic acetylcholine receptor beta2, isoform B K05312|1|3e-130|467|tca:658018|nicotinic acetylcholine receptor, invertebrate GO:0044459//plasma membrane part;GO:0016021//integral to membrane;GO:0044459//plasma membrane part;GO:0016021//integral to membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport 43867 7025.00 7.4 7.49 0.0174404479424389 Up 0.0573900409457139 Atf3 activating transcription factor 3, isoform C K09032|1|8e-09|64.3|dre:393939|activating transcription factor 3;K09033|5|3e-08|62.4|ecb:100057649|jun dimerization protein 2 - - - 5740282 3315.00 0.25 0.38 0.604071323668861 Up 0.110091137234183 CG34315 CG34315 K02605|1|0.0|1313|dme:Dmel_CG4088|origin recognition complex subunit 3 GO:0000808//origin recognition complex GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0008306//associative learning;GO:0030537//larval behavior 41262 4723.70 3.17 4.275 0.431441579633853 Up 0.311253467177387 sle slender lobes, isoform B K04574|1|2e-09|66.2|bta:528842|neurofilament heavy polypeptide;K09880|2|3e-09|65.5|aag:AaeL_AAEL000109|enolase-phosphatase E1 [EC:3.1.3.77] GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton - GO:0006997//nucleus organization;GO:0006997//nucleus organization 49529 1127.00 0.275 0.61 1.14937762403823 Up 0.205355963545106 ms(2)35Ci male sterile (2) 35Ci, isoform C - - - - 35245 817.00 0.405 0.27 -0.584962500721156 Down 0.11005811649716 CG13081 CG13081, isoform B - - - - 7354447 615.00 0.205 0.715 1.80231933216031 Up 0.27304847444195 SteXh:CG42398 SteXh:CG42398 K08282|1|6e-91|332|dme:Dmel_CG33237|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 14462754 644.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 33893 2078.00 10.33 5.005 -1.04539828002907 Down 0.609397701756703 CG42370 CG42370 K08635|1|5e-22|106|api:100162251|membrane metallo-endopeptidase-like 1;K01415|3|6e-20|99.4|nve:NEMVE_v1g229362|endothelin-converting enzyme [EC:3.4.24.71];K08636|5|8e-20|99.0|oaa:100083093|phosphate-regulating neutral endopeptidase [EC:3.4.24.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31661 980.00 1.07 1.41 0.398084365997647 Up 0.169693567560428 CG1958 CG1958 - - - - 14462544 318.00 2.15 1.3 -0.725825036561005 Down 0.301743494914807 318137 1318.00 0.24 0.18 -0.415037499278844 Down 0.0781931052701096 CG32642 CG32642, isoform E K13208|1|1e-06|44.7|dsi:Dsim_GD17091|ELAV like protein 2/3/4 - - - 35684 1901.00 1.85 2.33 0.332804684137968 Up 0.1962422401268 CG1602 CG1602 K09228|1|5e-35|149|mmu:630579|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 326209 2093.00 6.22 10.645 0.775189464321691 Up 0.561880861180822 S-Lap2 Sperm-Leucylaminopeptidase 2 K11142|1|0.0|1100|dme:Dmel_CG32351|cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5];K01255|2|0.0|994|dme:Dmel_CG6372|leucyl aminopeptidase [EC:3.4.11.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process;GO:0007420//brain development 40324 1081.00 11.775 13.355 0.181652916134965 Up 0.279982829216748 CG10584 CG10584 - - - - 12798539 879.00 3.72 3.485 -0.0941439652396084 Down 0.0993593977017567 CG43149 CG43149 - - - - 37270 493.12 358.455 277.785 -0.367823318217079 Down 0.586151102892617 Obp56g Odorant-binding protein 56g, isoform B - - - - 31675 2478.00 0.425 0.59 0.473252113224139 Up 0.118478404437987 CG11369 CG11369 - - - - 36511 1041.06 14.1 7.2 -0.969626350956481 Down 0.627360982697134 CG42807 CG42807, isoform B - - - - 32654 2996.00 0.59 1.07 0.858823937039305 Up 0.233489631488575 CG13008 CG13008 - - - - 43142 1495.00 0.335 0.485 0.533823651729355 Up 0.11596882842425 CG14546 CG14546 - - - - 3885650 1033.00 0.585 0.895 0.613451057680852 Up 0.172170122837142 Cp7Fa chorion protein a at 7F - - - - 41994 1635.42 5.855 5.875 0.00491968095114693 Up 0.0416061286487914 CG14882 CG14882, isoform B K00597|1|0.0|905|dme:Dmel_CG14882|[methionine synthase] reductase [EC:1.16.1.8] - - - 3772254 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33903 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 19835604 766.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 31927 1179.15 19.905 16.265 -0.291360049050218 Down 0.425075947695153 CG1791 CG1791, isoform C K10104|1|1e-39|163|dwi:Dwil_GK15354|ficolin - GO:0005515//protein binding;GO:0005515//protein binding GO:0023060;GO:0023060 31596 6300.68 35.09 35.57 0.0196010266596834 Up 0.0824527803460573 pigs pickled eggs, isoform C K10382|1|3e-11|72.0|bta:535297|dystonin - - - 42656 2109.17 173.15 170.325 -0.0237321807691843 Down 0.0920287940826839 CG5315 adiponectin receptor, isoform E K07297|1|0.0|660|dse:Dsec_GM23638|adiponectin receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity GO:0023033;GO:0006631//fatty acid metabolic process;GO:0023033;GO:0006631//fatty acid metabolic process;GO:0023033;GO:0006631//fatty acid metabolic process 32918 2134.06 7.405 8.69 0.230856441525552 Up 0.282162197860256 Hs3st-B heparan sulfate 3-O sulfotransferase-B, isoform B K07809|1|3e-145|515|cqu:CpipJ_CPIJ008491|[heparan sulfate]-glucosamine 3-sulfotransferase 3 [EC:2.8.2.30] - GO:0034483//heparan sulfate sulfotransferase activity GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0032535//regulation of cellular component size;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048592//eye morphogenesis;GO:0007033//vacuole organization;GO:0007166//cell surface receptor signaling pathway;GO:0010721//negative regulation of cell development 32461 3785.03 57.645 54.565 -0.07921962702857 Down 0.206049399022586 HDAC6 HDAC6, isoform G K11407|1|0.0|2078|dya:Dyak_GE17180|histone deacetylase 6/10 [EC:3.5.1.98] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding GO:0022900//electron transport chain;GO:0006476//protein deacetylation;GO:0010468//regulation of gene expression;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0006476//protein deacetylation;GO:0010468//regulation of gene expression;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0006476//protein deacetylation;GO:0010468//regulation of gene expression;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0006476//protein deacetylation;GO:0010468//regulation of gene expression;GO:0009060//aerobic respiration 36387 457.00 19.03 18.405 -0.0481778118899607 Down 0.123068286884163 spt4 spt4 K00869|1|0.0|725|dme:Dmel_CG33671|mevalonate kinase [EC:2.7.1.36] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0016301//kinase activity;GO:0003711//transcription elongation regulator activity;GO:0032559 GO:0006796//phosphate-containing compound metabolic process;GO:0006720//isoprenoid metabolic process;GO:0006351//transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process 43276 957.00 56.665 61.31 0.113664496948597 Up 0.26413287544578 CG42813 CG42813 K08077|1|3e-37|155|gga:423501|UDP-sugar diphosphatase [EC:3.6.1.45] - GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0043169//cation binding - 2768987 1425.00 0.03 0.11 1.87446911791614 Up 0.101968035926562 CG33289 pickpocket 5, isoform C K04832|1|1e-58|227|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04831|2|4e-07|56.2|dre:407668|amiloride-sensitive cation channel 4, pituitary;K04828|3|4e-06|52.8|ecb:100058355|amiloride-sensitive cation channel 1, neuronal (degenerin) GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 33973 840.00 15.39 16.915 0.136309945465778 Up 0.249900937788931 Gas41 Gas41 K11341|1|9e-129|459|dme:Dmel_CG9207|YEATS domain-containing protein 4 GO:0005667//transcription factor complex - GO:0006352//DNA-dependent transcription, initiation 34217 2461.71 0.835 0.04 -4.38370429247405 Down 0.407046625280676 CG9525 CG9525, isoform B - - - - 41114 4328.48 180.245 132.52 -0.443749131099556 Down 0.615671641791045 CG43674 CG45050, isoform I K12163|1|2e-11|71.6|tca:663257|AN1-type zinc finger and ubiquitin domain-containing protein 1 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 32649 910.72 1.36 2.335 0.779815898459323 Up 0.32680623431515 CG9673 CG9673, isoform B K01362|1|1e-38|160|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|2e-27|122|dpo:Dpse_GA14937|trypsin [EC:3.4.21.4];K11997|5|2e-26|119|ame:409206|tripartite motif-containing protein 2/3 - GO:0004175//endopeptidase activity GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway 33158 5590.13 64.82 42.305 -0.615610836059707 Down 0.652621846519614 Cda5 chitin deacetylase-like 5, isoform J K01183|1|4e-06|55.5|dpo:Dpse_GA17825|chitinase [EC:3.2.1.14];K01873|2|7e-06|54.7|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity;GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity;GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity;GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity GO:0006022;GO:0006022;GO:0006022;GO:0006022 41731 550.00 4.57 0.465 -3.29689154395004 Down 0.662990357944789 CG9616 CG9616 - - - - 33903 1988.53 101.845 59.755 -0.769243813293051 Down 0.694260995905429 mmy mummy, isoform D K00972|1|0.0|1004|dme:Dmel_CG9535|UDP-N-acetylglucosamine pyrophosphorylase [EC:2.7.7.23] - GO:0070569//uridylyltransferase activity;GO:0070569//uridylyltransferase activity GO:0043062//extracellular structure organization;GO:0016331//morphogenesis of embryonic epithelium;GO:0060541//respiratory system development;GO:0040003//chitin-based cuticle development;GO:0006031//chitin biosynthetic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007409//axonogenesis;GO:0035150//regulation of tube size;GO:0043062//extracellular structure organization;GO:0016331//morphogenesis of embryonic epithelium;GO:0060541//respiratory system development;GO:0040003//chitin-based cuticle development;GO:0006031//chitin biosynthetic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007409//axonogenesis;GO:0035150//regulation of tube size 318030 633.00 1.325 1.835 0.469787703392651 Up 0.215658433496236 CG32440 CG32440 - - - - 37004 2642.00 2.085 3.035 0.541649132811018 Up 0.300719852067098 CCHa1r CCHamide-1 receptor K04169|1|8e-52|204|mmu:14829|gastrin-releasing peptide receptor;K04168|4|1e-50|200|tgu:100228908|neuromedin B receptor - - - 35932 1324.84 74.8 40.46 -0.886541950216716 Down 0.704002113327169 CG8788 CG8788, isoform C - - - - 36461 2470.21 32.095 29.39 -0.127023202001326 Down 0.27664773477744 Dp DP transcription factor, isoform C K09394|1|0.0|768|dme:Dmel_CG4654|transcription factor Dp, invertebrate GO:0005667//transcription factor complex;GO:0031012//extracellular matrix;GO:0005667//transcription factor complex;GO:0031012//extracellular matrix GO:0051536//iron-sulfur cluster binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0004518//nuclease activity;GO:0004866//endopeptidase inhibitor activity;GO:0051536//iron-sulfur cluster binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0004518//nuclease activity;GO:0004866//endopeptidase inhibitor activity GO:0000278//mitotic cell cycle;GO:0006277//DNA amplification;GO:0040003//chitin-based cuticle development;GO:0003006//developmental process involved in reproduction;GO:0006355//regulation of transcription, DNA-dependent;GO:0007591//molting cycle, chitin-based cuticle;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007292//female gamete generation;GO:0060541//respiratory system development;GO:0043065//positive regulation of apoptotic process;GO:0000278//mitotic cell cycle;GO:0006277//DNA amplification;GO:0040003//chitin-based cuticle development;GO:0003006//developmental process involved in reproduction;GO:0006355//regulation of transcription, DNA-dependent;GO:0007591//molting cycle, chitin-based cuticle;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007292//female gamete generation;GO:0060541//respiratory system development;GO:0043065//positive regulation of apoptotic process 36686 1453.89 0.43 0.67 0.639824435755675 Up 0.149517897239466 CG8093 CG8093, isoform B K01046|1|0.0|827|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01052|4|1e-72|273|xtr:548564|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 35334 2391.24 22.22 31.915 0.522375831066693 Up 0.592557125875049 CG9317 CG9317, isoform C K08202|1|5e-84|312|dwi:Dwil_GK11735|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 8673962 876.00 58.985 42.5 -0.472885279715983 Down 0.602628450667019 CG42486 CG42486, isoform B - - GO:0004866//endopeptidase inhibitor activity - 12798468 405.00 1.56 14.175 3.18373080096734 Up 0.767335886936996 CG43101 CG43101 - - - - 32183 14189.15 19.99 23.885 0.256826404726638 Up 0.41021661603487 Ten-a tenascin accessory, isoform P K06252|1|1e-64|250|mdo:100013925|tenascin GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning;GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning;GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning;GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning;GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning;GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning;GO:0031589//cell-substrate adhesion;GO:0007365//periodic partitioning 19835448 527.00 0.56 0.575 0.038135128886771 Up 0.0418702945449742 5740837 1754.00 0.905 0.695 -0.380904814359698 Down 0.130630035662396 CG34425 CG34425 K04514|1|3e-11|70.5|rno:25537|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - GO:0032559 - 32978 956.00 0.425 0.145 -1.55140994101013 Down 0.192742042002377 CG14227 CG14227 K01362|1|2e-17|89.4|dpo:Dpse_GA18526| [EC:3.4.21.-];K01312|2|2e-17|89.4|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K09635|4|3e-17|89.0|rno:367074|transmembrane protease, serine 4 [EC:3.4.21.-];K01344|5|4e-17|88.6|gga:395085|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42965 963.50 0.85 1.575 0.889817082249577 Up 0.290153216219786 CG10899 CG10899, isoform C K01672|1|4e-167|587|dme:Dmel_CG10899|carbonic anhydrase [EC:4.2.1.1];K01743|1|4e-167|587|dme:Dmel_CG10899| [EC:4.2.-.-] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 41451 1055.00 1.18 0.37 -1.67318968373289 Down 0.338759741117422 CG10005 CG10005, isoform B - - - - 318625 1634.00 1.16 1.93 0.734476042140508 Up 0.288171971998415 CG31204 CG31204 - - - - 41697 2478.00 2.17 1.815 -0.257725494448729 Down 0.157178708228768 ems empty spiracles K09317|1|2e-171|602|dme:Dmel_CG2988|homeobox protein EMX - - - 10178866 945.00 1.905 4.53 1.24972005255291 Up 0.522718267071721 CG42855 CG42855 - - - - 35338 1961.00 12.33 14.285 0.212328236533533 Up 0.317923656056003 ns4 nucleostemin ortholog 4 - GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding - 3885579 448.00 19.465 6.145 -1.66339742897462 Down 0.716219786025624 CG42821 CG42821 - - - - 19836016 903.00 2.07 3.095 0.580308641714939 Up 0.315315017831198 50374 639.58 13.435 33.43 1.31514703360424 Up 0.720677585523709 CG17777 CG17777, isoform C - - - - 32151 1115.21 13.815 15.395 0.156226305232325 Up 0.267170783251882 CG15738 severe impairment of CI with lengthened youth, isoform B - - GO:0003824//catalytic activity GO:0008152//metabolic process 41917 987.74 22.79 29.125 0.353857125163708 Up 0.503731343283582 Arpc3A Actin-related protein 2/3 complex, subunit 3A, isoform E K05756|1|2e-97|355|dsi:Dsim_GD19052|actin related protein 2/3 complex, subunit 3 - - - 40834 1774.00 0.025 0.05 1 Up 0.0577202483159424 ftz fushi tarazu K09311|1|0.0|661|dme:Dmel_CG2047|Antp family, other GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007276//gamete generation;GO:0006355//regulation of transcription, DNA-dependent;GO:0035287//head segmentation;GO:0045165//cell fate commitment;GO:0007399//nervous system development;GO:0007365//periodic partitioning 32505 910.56 20.375 24.56 0.269510501364377 Up 0.423325848632941 CG9240 CG9240, isoform B K09647|1|1e-93|343|dme:Dmel_CG9240|mitochondrial inner membrane protease subunit 1 [EC:3.4.99.-] GO:0031224//intrinsic to membrane GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process 37850 1000.10 81.375 74.105 -0.135014751187842 Down 0.320268128384626 Rap2l Ras-associated protein 2-like, isoform D K07974|1|3e-58|225|cel:C25D7.7|Ras family, other;K07839|2|2e-57|223|mdo:100022678|Ras-related protein Rap-2C;K07837|3|6e-57|221|tgu:100227479|Ras-related protein Rap-2A GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction;GO:0019827//stem cell maintenance 38530 863.00 39.6 26.2 -0.595933618542159 Down 0.627460044908202 CG1319 CG1319 - GO:0031980 GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding - 40577 807.42 30.2 33.26 0.139239619074828 Up 0.293587372870162 MED31 mediator complex subunit 31, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0000578//embryonic axis specification;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0000578//embryonic axis specification 19835270 402.00 5.44 6.14 0.17463200411984 Up 0.198982961299696 12798326 371.00 5.6 9.88 0.819084214639711 Up 0.560989301281205 CG43107 CG43107 - - - - 14462499 1368.00 1.62 1.32 -0.295455883526171 Down 0.15037643640206 3772552 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33833 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 50070 14002.51 22.49 26.205 0.220558447860099 Up 0.378912957337208 mask multiple ankyrin repeats single KH domain, isoform F K10380|1|3e-60|236|dre:794638|ankyrin GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - GO:0001745//compound eye morphogenesis;GO:0006959//humoral immune response;GO:0007010//cytoskeleton organization;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0001745//compound eye morphogenesis;GO:0006959//humoral immune response;GO:0007010//cytoskeleton organization;GO:0007167//enzyme linked receptor protein signaling pathway 41678 2164.00 59.635 39.065 -0.610282688072395 Down 0.647734777440232 ninaB neither inactivation nor afterpotential B K10252|1|1e-84|314|tgu:100220531|beta,beta-carotene 9',10'-dioxygenase [EC:1.14.99.-];K00515|2|2e-81|303|gga:395346|beta-carotene 15,15'-monooxygenase [EC:1.14.99.36] - - - 39954 3769.43 11.33 12.025 0.0858890328368886 Up 0.160348698982961 Oatp74D organic anion transporting polypeptide 74D, isoform E - GO:0044464//cell part;GO:0044464//cell part GO:0008509//anion transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity GO:0006820//anion transport;GO:0006820//anion transport 35727 575.00 0.48 1.165 1.27922364393312 Up 0.299828292167481 CG12824 CG12824, isoform B - - - - 38982 1227.00 13.485 14.415 0.096215315259303 Up 0.183430194161934 Nelf-E negative elongation factor E - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003723//RNA binding GO:0000122//negative regulation of transcription from RNA polymerase II promoter 19835177 887.00 0.54 0.395 -0.451106753986366 Down 0.113888521991811 40191 14274.05 13.475 15.4 0.192645077942396 Up 0.305111610091137 kug kugelei, isoform E K06813|1|0.0|775|gga:423718|cadherin 23 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//cell-cell adhesion;GO:0016337//cell-cell adhesion 31195 1791.00 16.65 16.285 -0.0319784575627211 Down 0.0906419231277242 Nmd3 Nonsense-mediated mRNA 3 K07562|1|0.0|977|dme:Dmel_CG3460|nonsense-mediated mRNA decay protein 3 - - - 14462686 1704.00 0.01 0.08 3 Up 0.110718531237617 317911 1773.00 0.215 0.215 0 - 0.0382380134724607 CG32201 CG32201 K00472|1|0.0|1043|dme:Dmel_CG32201|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 32084 1587.00 0.575 0.885 0.622115499138622 Up 0.172533350944393 CG15196 CG15196, isoform C - - - - 19835514 980.00 0.51 0.205 -1.31487333735341 Down 0.195945053493594 42002 2784.00 2.205 2.3 0.0608552053868546 Up 0.0647536653018095 Gyc-89Db guanylyl cyclase at 89Db K01769|1|0.0|1164|dwi:Dwil_GK14484|guanylate cyclase, other [EC:4.6.1.2] - - - 14462825 756.00 0.275 0.3 0.125530882083859 Up 0.0538238013472461 36182 621.00 2.04 0.67 -1.60633615151372 Down 0.427816668868049 CG13215 CG13215 - - - - 36105 2591.00 1.325 1.105 -0.26194599005913 Down 0.120657773081495 Cyp49a1 Cyp49a1, isoform E K00517|1|1e-124|447|dme:Dmel_CG8587| [EC:1.14.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 43050 1345.00 1.295 1.19 -0.12199052437861 Down 0.0750891559899617 CG11878 CG11878 - - - - 43018 3270.00 15.515 15.87 0.032638431306463 Up 0.0906419231277242 Clbn caliban, isoform C - - - - 33420 1223.13 88.795 66.63 -0.414306547853406 Down 0.587736098269713 CG3597 CG3597, isoform B K00078|1|3e-65|249|cin:100186038|dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179] - GO:0003824//catalytic activity GO:0008152//metabolic process 40615 902.00 32.855 18.125 -0.858131946996575 Down 0.669561484612337 CG2022 CG2022 K13349|1|1e-54|213|cqu:CpipJ_CPIJ004063|Mpv17-like protein;K13348|2|3e-45|182|dmo:Dmoj_GI16042|protein Mpv17 GO:0031224//intrinsic to membrane - - 32689 1067.00 0.115 0.085 -0.436099114806673 Down 0.0616827367586845 CG43996 CG43996 - - - - 12797898 1195.00 0.1 0.15 0.584962500721156 Up 0.075023114515916 42027 1179.94 63.37 84.825 0.420689509404489 Up 0.591698586712455 CG10326 CG10326, isoform B - - - - 3354915 396.00 0.01 1.2 6.90689059560852 Up 0.543752476555277 CG40204 CG40204 K10359|1|3e-06|50.1|cel:T10H10.1|myosin VII GO:0043232 GO:0005488//binding GO:0023060 42453 1376.69 5.78 6.835 0.241871845105381 Up 0.262250693435477 cdc2c cdc2c, isoform C K07760|1|4e-174|610|dme:Dmel_CG10498|cyclin-dependent kinase [EC:2.7.11.22];K02206|3|7e-108|390|nvi:100117828|cyclin-dependent kinase 2 [EC:2.7.11.22];K02088|5|3e-105|381|mdo:100027005|cyclin-dependent kinase 3 [EC:2.7.11.22] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0007243//intracellular protein kinase cascade;GO:0022402//cell cycle process;GO:0006464//cellular protein modification process;GO:0007243//intracellular protein kinase cascade;GO:0022402//cell cycle process;GO:0006464//cellular protein modification process;GO:0007243//intracellular protein kinase cascade;GO:0022402//cell cycle process;GO:0006464//cellular protein modification process 318956 1369.00 9.94 9.675 -0.0389841905305137 Down 0.0896182802800159 CG31812 CG31812 K01170|1|2e-133|475|dme:Dmel_CG31812|tRNA-intron endonuclease [EC:3.1.27.9] - GO:0005488//binding;GO:0004549//tRNA-specific ribonuclease activity GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation 19835585 649.00 2.78 1.305 -1.09103507615362 Down 0.416160348698983 34607 2300.00 7.32 3.4 -1.10630890214634 Down 0.574395720512482 CG16965 CG16965 - - - GO:0044238//primary metabolic process 48571 6252.64 42.635 47.75 0.163462476527996 Up 0.336745476159028 heph hephaestus, isoform Z K13218|1|0.0|1055|dme:Dmel_CG31000|polypyrimidine tract-binding protein 1 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0007017//microtubule-based process;GO:0000377;GO:0007476//imaginal disc-derived wing morphogenesis 53435 1246.00 19.89 14.3 -0.476028129167992 Down 0.538799366001849 c12.1 c12.1 K12863|1|2e-91|335|dme:Dmel_CG12135|protein CWC15 GO:0005681//spliceosomal complex - GO:0000278//mitotic cell cycle;GO:0000377 19836110 774.00 0.055 0.12 1.12553088208386 Up 0.0856557918372738 42597 1189.00 7.785 11.195 0.524085583773561 Up 0.491381587637036 CG13408 CG13408 - - - - 19835528 187.00 2.15 1.86 -0.209034038481429 Down 0.133535860520407 5740320 3145.39 45.265 42.585 -0.088050604613375 Down 0.219125610883635 uex unextended, isoform H - - - - 35438 443.00 0.845 0.53 -0.672958981718985 Down 0.173986263373398 CG10834 CG10834 K10419|1|6e-21|99.0|phu:Phum_PHUM551150|dynein light chain roadblock-type GO:0005875//microtubule associated complex GO:0016887//ATPase activity GO:0007017//microtubule-based process 38392 925.00 9.46 6.83 -0.469954605049305 Down 0.446605468234051 CG32271 CG32271 K01312|1|6e-39|160|dme:Dmel_CG18444|trypsin [EC:3.4.21.4];K09635|4|1e-37|156|dre:777630|transmembrane protease, serine 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835974 372.00 0.235 0.39 0.730813367184611 Up 0.125511821423854 34360 1392.15 9.175 11.355 0.307547642976313 Up 0.378879936600185 CG4908 CG4908, isoform B K08900|1|0.0|843|dse:Dsec_GM18016|mitochondrial chaperone BCS1 GO:0019866//organelle inner membrane;GO:0019866//organelle inner membrane GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 37118 3594.00 7.165 8.015 0.161735815892403 Up 0.212488442742042 CG12263 CG12263 K05288|1|0.0|1774|dpo:Dpse_GA11517|phosphatidylinositol glycan, class O - - - 40350 1523.10 0.765 0.56 -0.450032920635048 Down 0.130762118610487 CG12974 CG12974, isoform D - - - - 44631 1027.47 3.295 6.41 0.960045891610689 Up 0.531072513538502 Ag5r antigen 5-related, isoform C K02330|1|2e-06|53.5|tca:656359|DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-] - - - 32556 2212.47 49.72 47.31 -0.0716811355408184 Down 0.185081231013076 Stim stromal interaction molecule, isoform G K02084|1|3e-06|54.3|spu:591503|apoptotic protease-activating factor GO:0016020//membrane;GO:0016020//membrane GO:0005218//intracellular ligand-gated calcium channel activity;GO:0046872//metal ion binding;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0046872//metal ion binding GO:0032236;GO:0007472//wing disc morphogenesis;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0007423//sensory organ development;GO:0032236;GO:0007472//wing disc morphogenesis;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0007423//sensory organ development 32496 1569.00 0.195 0.4 1.03652587602511 Up 0.151466120723815 CG8105 CG8105 K01077|1|0.0|923|dme:Dmel_CG8105|alkaline phosphatase [EC:3.1.3.1] - GO:0042578//phosphoric ester hydrolase activity - 8674036 421.00 0.105 0.45 2.09953567355091 Up 0.225498613129045 CG42615 CG42615 - - - - 42637 6384.00 2.125 2.4 0.175571564583455 Up 0.127757231541408 CG12499 CG12499 - - - - 10178859 577.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 CG42728 CG42728 - - GO:0030247//polysaccharide binding GO:0006022 41925 2986.00 28.035 26.95 -0.0569437968264462 Down 0.1524567428345 Hmt-1 heavy metal tolerance factor 1 K05663|1|0.0|1558|dme:Dmel_CG4225|mitochondrial ABC transporter ATM;K05661|2|0.0|812|bfo:BRAFLDRAFT_76408|ATP-binding cassette, subfamily B (MDR/TAP), member 6 - - - 32315 3043.00 6.965 7.235 0.0548696639304718 Up 0.0935807687227579 CG11178 CG11178, isoform C - - - - 50458 384.00 0.01 0.155 3.95419631038688 Up 0.171410645885616 CG4440 CG4440, isoform B - - - - 31266 1728.00 19.51 20.55 0.074924615960019 Up 0.161537445515784 ttm50 tiny tim 50 K01090|1|6e-17|89.4|dre:553744|protein phosphatase [EC:3.1.3.16] - - - 43990 1704.00 0.34 0.71 1.06228427825434 Up 0.212521463479065 Sep5 septin 5, isoform B K04557|1|3e-69|263|xla:779425|peanut-like protein 1 (cell division control related protein 1) GO:0032156;GO:0045171//intercellular bridge;GO:0015630//microtubule cytoskeleton;GO:0032156;GO:0045171//intercellular bridge;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0007275//multicellular organismal development;GO:0051301//cell division;GO:0007275//multicellular organismal development;GO:0051301//cell division 35882 1904.00 29.86 29.03 -0.0406695935078795 Down 0.119237881389513 CG8258 CG8258 K09500|1|0.0|942|dme:Dmel_CG8258|T-complex protein 1 subunit theta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0044267//cellular protein metabolic process 40675 2587.24 49.51 52.315 0.0795047127150693 Up 0.204332320697398 CRMP collapsin response mediator protein, isoform E K01464|1|0.0|1107|dse:Dsec_GM10816|dihydropyrimidinase [EC:3.5.2.2] - GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0006351//transcription, DNA-dependent;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0023060;GO:0006351//transcription, DNA-dependent;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0023060 31681 2226.00 6.525 6.685 0.0349496586361061 Up 0.071060626073174 NELF-B NELF-B - - - - 12798586 479.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 8673999 418.00 0.09 0.345 1.93859945533586 Up 0.18940694756307 CG42577 CG42577 - - - - 37444 1613.00 3.435 2.725 -0.334053869153811 Down 0.239400343415665 EfSec EfSec K02358|1|2e-30|134|api:100160055|elongation factor EF-Tu [EC:3.6.5.3] - - - 326191 575.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG32073 CG32073, isoform B - - - - 32106 1749.07 6.9 7.85 0.186096292113458 Up 0.2342491084401 CG11695 CG11695, isoform B K09228|1|6e-32|139|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 40781 778.00 32.3 31.395 -0.0409993526044216 Down 0.120789856029587 SmD2 small ribonucleoprotein particle protein SmD2 K11096|1|5e-54|210|dpe:Dper_GL23477|small nuclear ribonucleoprotein D2 GO:0032991//macromolecular complex GO:0005488//binding - 36101 848.00 38.505 12.93 -1.57432352148632 Down 0.741051380266808 CG12896 CG12896 K00430|1|1e-127|455|dme:Dmel_CG12405|peroxidase [EC:1.11.1.7] GO:0044444//cytoplasmic part GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0019725//cellular homeostasis 39861 1825.00 0.68 0.69 0.0210616155278296 Up 0.0413749834896315 Galpha73B G protein alpha f subunit K04640|1|0.0|814|dme:Dmel_CG12232|guanine nucleotide binding protein (G protein), alpha, other GO:0019897//extrinsic to plasma membrane GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0007166//cell surface receptor signaling pathway;GO:0009888//tissue development;GO:0023060 36041 3789.11 80.4 75.85 -0.0840463209318953 Down 0.211828028001585 Pka-R2 cAMP-dependent protein kinase R2, isoform E K04739|1|0.0|692|dya:Dyak_GE21875|cAMP-dependent protein kinase regulator GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part GO:0005488//binding;GO:0019887//protein kinase regulator activity;GO:0005488//binding;GO:0019887//protein kinase regulator activity;GO:0005488//binding;GO:0019887//protein kinase regulator activity;GO:0005488//binding;GO:0019887//protein kinase regulator activity GO:0006468//protein phosphorylation;GO:0023060;GO:0006935//chemotaxis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0030534//adult behavior;GO:0006468//protein phosphorylation;GO:0023060;GO:0006935//chemotaxis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0030534//adult behavior;GO:0006468//protein phosphorylation;GO:0023060;GO:0006935//chemotaxis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0030534//adult behavior;GO:0006468//protein phosphorylation;GO:0023060;GO:0006935//chemotaxis;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0030534//adult behavior 5740214 314.00 1.26 1.27 0.0114047632722493 Up 0.041044776119403 CG34170 CG34170, isoform B - - - - 43314 5099.00 1.845 2.16 0.227410496103073 Up 0.14354114383833 CG5639 CG5639 K02599|1|9e-10|67.0|mdo:100025710|Notch;K06826|2|9e-10|67.0|ecb:100067227|nidogen (entactin);K10809|3|2e-09|66.2|cfa:482047|thyroglobulin - GO:0004866//endopeptidase inhibitor activity - 43991 2478.96 23.34 23.975 0.0387262541981453 Up 0.114020604939902 Pten pten, isoform H K01110|1|0.0|1011|dme:Dmel_CG5671|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase [EC:3.1.3.67] - GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process;GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process;GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process;GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process;GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process;GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process;GO:0006020//inositol metabolic process;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0012501//programmed cell death;GO:0045926//negative regulation of growth;GO:0030384;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0006796//phosphate-containing compound metabolic process;GO:0002168//instar larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051726//regulation of cell cycle;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006950//response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0042051//compound eye photoreceptor development;GO:0010876//lipid localization;GO:0016477//cell migration;GO:0044248//cellular catabolic process 36841 1527.00 0.35 0.505 0.528928465806829 Up 0.120261524237221 CG15925 CG15925 - - - - 317813 1389.00 2.545 2.595 0.0280688822821855 Up 0.0530643243957205 CG18789 CG18789 - - GO:0005488//binding - 35742 3550.82 67.825 63.8 -0.0882607185169966 Down 0.227578919561485 lin19 cullin 1, isoform D K03347|1|0.0|1584|der:Dere_GG23311|cullin 1 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 19834747 799.00 0.105 0.07 -0.584962500721156 Down 0.0687491744815744 33472 824.00 0.875 2.885 1.72121639681315 Up 0.499405626733589 CG15399 CG15399 K07976|1|8e-131|466|dme:Dmel_CG15399|Rab family, other GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 34629 2456.35 0.215 0.325 0.596103058326357 Up 0.102001056663585 prd paired, isoform B K09381|1|0.0|960|dsi:Dsim_GD22133|paired box protein 3/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006355//regulation of transcription, DNA-dependent;GO:0007365//periodic partitioning;GO:0006355//regulation of transcription, DNA-dependent;GO:0007365//periodic partitioning 19834790 412.00 0.525 0.37 -0.504792152037173 Down 0.115275392946771 14462713 471.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 31728 2637.58 92.395 94.39 0.0308192420117859 Up 0.111577070400211 Ubc-E2H Ubc-E2H, isoform C K10576|1|5e-91|335|dya:Dyak_GE17485|ubiquitin-conjugating enzyme E2 H [EC:6.3.2.19] - - - 14462724 267.00 2.495 3.29 0.399047768397981 Up 0.262911108175934 40471 1882.00 11.88 15.24 0.359328066692556 Up 0.449577334566107 CG11426 CG11426 K01080|1|2e-170|598|dme:Dmel_CG11426|phosphatidate phosphatase [EC:3.1.3.4] GO:0044464//cell part GO:0016791//phosphatase activity GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process 2768904 607.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 Ste:CG33247 Ste:CG33247 K08282|1|2e-95|347|dme:Dmel_CG33247|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 19834954 902.00 0.05 0.15 1.58496250072116 Up 0.1121384229296 37770 2106.00 33.775 34.365 0.0249841898127842 Up 0.0843019416193369 CG4797 CG4797 K08145|1|8e-56|218|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane - GO:0006810//transport 317903 2087.93 9.455 6.76 -0.484054211667577 Down 0.45169066173557 CG32191 CG32191, isoform C K01135|1|1e-143|510|dme:Dmel_CG7402|arylsulfatase B [EC:3.1.6.12] - GO:0016788//hydrolase activity, acting on ester bonds - 32416 3679.00 0.435 0.42 -0.0506260730699681 Down 0.0451063267732136 CG9518 CG9518, isoform C K00108|1|0.0|1308|dme:Dmel_CG9518|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 36213 5871.00 0.04 0.025 -0.678071905112638 Down 0.0550785893541144 sha shavenoid, isoform C - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - GO:0009987//cellular process;GO:0003002//regionalization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0009987//cellular process;GO:0003002//regionalization;GO:0008544//epidermis development;GO:0007476//imaginal disc-derived wing morphogenesis 59223 2706.05 14.19 15.015 0.0815298854965982 Up 0.160612864879144 CG18769 CG18769, isoform I - GO:0043231//intracellular membrane-bounded organelle - - 41351 1263.00 5.53 4.685 -0.23923043257552 Down 0.236626601505746 CG17187 CG17187 K09537|1|6e-143|507|dme:Dmel_CG17187|DnaJ homolog subfamily C member 17 GO:0005681//spliceosomal complex GO:0005515//protein binding GO:0000377;GO:0044267//cellular protein metabolic process 43697 2925.31 21.765 21.365 -0.026760703106789 Down 0.0926231673490952 qless qless, isoform B K12504|1|0.0|864|dme:Dmel_CG31005|decaprenyl diphosphate synthase subunit 1 [EC:2.5.1.-] - GO:0003824//catalytic activity;GO:0005488//binding GO:0006720//isoprenoid metabolic process 33884 1449.54 32.94 38.375 0.220326195418549 Up 0.401565182934883 CG9497 CG9497, isoform B - - - - 33432 3940.38 9.065 7.015 -0.369863916124259 Down 0.389050323603223 dpp decapentaplegic, isoform E K04662|1|0.0|932|dme:Dmel_CG9885|bone morphogenetic protein 2/4 GO:0044464//cell part;GO:0044421//extracellular region part;GO:0044464//cell part;GO:0044421//extracellular region part;GO:0044464//cell part;GO:0044421//extracellular region part;GO:0044464//cell part;GO:0044421//extracellular region part GO:0005126//cytokine receptor binding;GO:0016564//transcription repressor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0005126//cytokine receptor binding;GO:0016564//transcription repressor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0005126//cytokine receptor binding;GO:0016564//transcription repressor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0005126//cytokine receptor binding;GO:0016564//transcription repressor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0035167//larval lymph gland hemopoiesis;GO:0008595//anterior/posterior axis specification, embryo;GO:0006915//apoptotic process;GO:0001745//compound eye morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0051301//cell division;GO:0035028;GO:0030703//eggshell formation;GO:0007310//oocyte dorsal/ventral axis specification;GO:0035151//regulation of tube size, open tracheal system;GO:0045704;GO:0048634;GO:0035153//epithelial cell type specification, open tracheal system;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0008283//cell proliferation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0019827//stem cell maintenance;GO:0042386//hemocyte differentiation;GO:0035051//cardiocyte differentiation;GO:0035167//larval lymph gland hemopoiesis;GO:0008595//anterior/posterior axis specification, embryo;GO:0006915//apoptotic process;GO:0001745//compound eye morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0051301//cell division;GO:0035028;GO:0030703//eggshell formation;GO:0007310//oocyte dorsal/ventral axis specification;GO:0035151//regulation of tube size, open tracheal system;GO:0045704;GO:0048634;GO:0035153//epithelial cell type specification, open tracheal system;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0008283//cell proliferation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0019827//stem cell maintenance;GO:0042386//hemocyte differentiation;GO:0035051//cardiocyte differentiation;GO:0035167//larval lymph gland hemopoiesis;GO:0008595//anterior/posterior axis specification, embryo;GO:0006915//apoptotic process;GO:0001745//compound eye morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0051301//cell division;GO:0035028;GO:0030703//eggshell formation;GO:0007310//oocyte dorsal/ventral axis specification;GO:0035151//regulation of tube size, open tracheal system;GO:0045704;GO:0048634;GO:0035153//epithelial cell type specification, open tracheal system;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0008283//cell proliferation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0019827//stem cell maintenance;GO:0042386//hemocyte differentiation;GO:0035051//cardiocyte differentiation;GO:0035167//larval lymph gland hemopoiesis;GO:0008595//anterior/posterior axis specification, embryo;GO:0006915//apoptotic process;GO:0001745//compound eye morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0051301//cell division;GO:0035028;GO:0030703//eggshell formation;GO:0007310//oocyte dorsal/ventral axis specification;GO:0035151//regulation of tube size, open tracheal system;GO:0045704;GO:0048634;GO:0035153//epithelial cell type specification, open tracheal system;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0008283//cell proliferation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0019827//stem cell maintenance;GO:0042386//hemocyte differentiation;GO:0035051//cardiocyte differentiation 35549 1849.00 5.955 4.77 -0.320112241858603 Down 0.303328490291903 CG30431 CG30431 K09228|1|1e-34|147|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 32226 1966.48 9.71 9.745 0.00519088983869734 Up 0.0453704926693964 CG4004 CG4004, isoform E - - - - 39066 1590.00 31.46 40.97 0.381049222064614 Up 0.543521331396117 CG34455 pyridoxal kinase K00868|1|1e-171|603|dme:Dmel_CG34455|pyridoxine kinase [EC:2.7.1.35] - GO:0016301//kinase activity GO:0008614//pyridoxine metabolic process 117488 1176.00 0.01 0.04 2 Up 0.0694426099590543 Gr36a gustatory receptor 36a K08471|1|7e-97|353|dme:Dmel_CG31744|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 31904 1987.39 26.395 30.97 0.230606717004035 Up 0.399517897239466 Aats-lys Lysyl-tRNA synthetase, isoform C K04567|1|0.0|1086|dsi:Dsim_GD16054|lysyl-tRNA synthetase, class II [EC:6.1.1.6] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 40137 1693.00 73.205 48.015 -0.608457012282452 Down 0.653942676000528 CG9372 CG9372 K09637|1|1e-35|151|mmu:71753|transmembrane protease, serine 6 [EC:3.4.21.-];K01312|3|1e-34|147|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01344|4|2e-34|147|xtr:548476|protein C (activated) [EC:3.4.21.69];K09641|5|2e-34|147|bta:521615|transmembrane protease, serine 11D [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39169 2040.28 55.34 56.41 0.0276282929949083 Up 0.107251353850218 nudE nudE, isoform F K06560|1|2e-19|97.4|smm:Smp_169560|mannose receptor, C type;K04648|2|1e-06|55.1|dre:407638|dynactin 1;K10357|3|2e-06|54.7|mdo:100031389|myosin V;K06638|4|3e-06|53.9|ecb:100058904|mitotic spindle assembly checkpoint protein MAD1;K12478|5|4e-06|53.5|cin:751565|early endosome antigen 1 GO:0031967;GO:0000922//spindle pole;GO:0000775//chromosome, centromeric region;GO:0012505//endomembrane system;GO:0031967;GO:0000922//spindle pole;GO:0000775//chromosome, centromeric region;GO:0012505//endomembrane system;GO:0031967;GO:0000922//spindle pole;GO:0000775//chromosome, centromeric region;GO:0012505//endomembrane system;GO:0031967;GO:0000922//spindle pole;GO:0000775//chromosome, centromeric region;GO:0012505//endomembrane system GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0051640//organelle localization;GO:0000070//mitotic sister chromatid segregation;GO:0007051//spindle organization;GO:0007140//male meiosis;GO:0051640//organelle localization;GO:0000070//mitotic sister chromatid segregation;GO:0007051//spindle organization;GO:0007140//male meiosis;GO:0051640//organelle localization;GO:0000070//mitotic sister chromatid segregation;GO:0007051//spindle organization;GO:0007140//male meiosis;GO:0051640//organelle localization;GO:0000070//mitotic sister chromatid segregation;GO:0007051//spindle organization;GO:0007140//male meiosis 318914 2831.00 0.38 0.91 1.25986712675511 Up 0.263472460705323 mthl15 methuselah-like 15, isoform D K04599|1|1e-24|115|dme:Dmel_CG6530|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004672//protein kinase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding;GO:0004672//protein kinase activity;GO:0004888//transmembrane signaling receptor activity GO:0050896//response to stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0007166//cell surface receptor signaling pathway 43616 2833.53 81.74 78.3 -0.0620299358422554 Down 0.174019284110421 aralar1 aralar1, isoform F K04257|1|2e-44|181|cfa:485348|olfactory receptor;K03454|2|2e-25|118|nve:NEMVE_v1g242628|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0005215//transporter activity;GO:0046872//metal ion binding;GO:0005215//transporter activity;GO:0046872//metal ion binding;GO:0005215//transporter activity;GO:0046872//metal ion binding;GO:0005215//transporter activity GO:0046907//intracellular transport;GO:0046907//intracellular transport;GO:0046907//intracellular transport;GO:0046907//intracellular transport 32363 2116.00 0.055 0.065 0.241008099503795 Up 0.0461960110949676 CG11584 CG11584, isoform C K09993|1|3e-06|54.3|hsa:1028|cyclin-dependent kinase inhibitor 1C - - - 36071 2984.16 14.67 21.84 0.574103985246463 Up 0.582320697397966 KCNQ KCNQ potassium channel, isoform K K05324|1|0.0|1732|dse:Dsec_GM20548|potassium voltage-gated channel KQT-like subfamily, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005267//potassium channel activity;GO:0005267//potassium channel activity;GO:0005267//potassium channel activity;GO:0005267//potassium channel activity GO:0009792//embryo development ending in birth or egg hatching;GO:0006941//striated muscle contraction;GO:0030001//metal ion transport;GO:0008016//regulation of heart contraction;GO:0009792//embryo development ending in birth or egg hatching;GO:0006941//striated muscle contraction;GO:0030001//metal ion transport;GO:0008016//regulation of heart contraction;GO:0009792//embryo development ending in birth or egg hatching;GO:0006941//striated muscle contraction;GO:0030001//metal ion transport;GO:0008016//regulation of heart contraction;GO:0009792//embryo development ending in birth or egg hatching;GO:0006941//striated muscle contraction;GO:0030001//metal ion transport;GO:0008016//regulation of heart contraction 32213 1544.00 2.12 2.82 0.411630897835594 Up 0.246929071456875 CG11085 CG11085 K09360|1|2e-19|97.4|dre:553186|BarH-like GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 33219 2397.68 83.9 83.445 -0.00784520435241701 Down 0.0664377228899749 crq croquemort, isoform E K13885|1|1e-56|221|ssc:397018|scavenger receptor class B, member 1;K12384|5|6e-56|219|bta:533177|lysosome membrane protein 2 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0006909//phagocytosis;GO:0002252;GO:0048102//autophagic cell death;GO:0030100//regulation of endocytosis;GO:0002274;GO:0006950//response to stress;GO:0006909//phagocytosis;GO:0002252;GO:0048102//autophagic cell death;GO:0030100//regulation of endocytosis;GO:0002274;GO:0006950//response to stress 12797896 1940.00 4.1 4.675 0.189342455269553 Up 0.18663320565315 41927 5256.00 6.95 5.36 -0.374779977153098 Down 0.353387927618544 CG31183 CG31183, isoform B K12323|1|0.0|2645|dme:Dmel_CG31183|atrial natriuretic peptide receptor A [EC:4.6.1.2] - - - 41660 1026.00 0.12 0.01 -3.58496250072116 Down 0.14562145027077 CG14369 CG14369 - - - - 246513 481.00 1202.93 824.28 -0.54534629730279 Down 0.666292431647074 CG30197 CG30197 - - GO:0004857//enzyme inhibitor activity - 35778 1516.64 3.06 4.35 0.507483748043439 Up 0.344736494518558 CG8712 CG8712, isoform B - - - - 5740154 584.00 1.745 1.34 -0.38099403575188 Down 0.183232069739797 CG34222 CG34222 K06826|1|3e-28|124|dse:Dsec_GM21210|nidogen (entactin) GO:0044464//cell part GO:0046872//metal ion binding GO:0031589//cell-substrate adhesion;GO:0006464//cellular protein modification process 33388 1707.00 11.265 12.495 0.149503587851276 Up 0.240886276581693 CG11723 CG11723, isoform B - - GO:0003676//nucleic acid binding - 36048 2782.61 21.39 15.725 -0.443876465398393 Down 0.529091269317131 magu magu, isoform F K08136|1|5e-11|70.5|xtr:100124745|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican);K06254|4|1e-05|52.8|ame:408393|agrin - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - 19834750 417.00 0.51 0.01 -5.6724253419715 Down 0.364020604939902 19835751 1036.00 0.045 0.255 2.50250034052918 Up 0.175769383172632 37043 2084.38 94.495 87.605 -0.10922478115945 Down 0.270704002113327 Mapmodulin mapmodulin, isoform D K11092|1|2e-09|64.7|aga:AgaP_AGAP007670|U2 small nuclear ribonucleoprotein A' GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0004857//enzyme inhibitor activity GO:0051169//nuclear transport 45871 1894.00 12.63 12.325 -0.0352669925222783 Down 0.0932175406155065 grau grauzone K09228|1|6e-39|162|ptr:455885|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007126//meiosis;GO:0001775//cell activation;GO:0006355//regulation of transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction 31759 746.00 13.545 10.72 -0.337455487744242 Down 0.422434288733325 CG2147 CG2147 - - - - 42495 1267.00 0.065 0.04 -0.700439718141092 Down 0.0550785893541144 CG7056 HHEX ortholog K08024|1|2e-85|315|dpo:Dpse_GA20065|homeobox protein HEX GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 38480 550.00 2.575 3.155 0.293067572911968 Up 0.208426892088231 Dpy-30L2 Dpy-30-like 2, isoform B - - - - 37097 627.00 2.97 1.13 -1.39414015838558 Down 0.470314357416458 CG18540 CG18540 - - - - 38219 3878.00 0.365 0.355 -0.0400774393753352 Down 0.0418702945449742 Oseg4 outer segment 4, isoform B K10751|1|4e-06|54.7|nve:NEMVE_v1g112997|chromatin assembly factor 1 subunit B GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane GO:0016740//transferase activity GO:0042384//cilium assembly;GO:0006497//protein lipidation 40109 2332.00 0.07 0.055 -0.347923303420307 Down 0.0540219257693832 CG14087 male sterile (3) 76Ba - - GO:0003676//nucleic acid binding - 326240 815.78 8.87 13.485 0.604349511934539 Up 0.542431647074363 CG32803 CG32803, isoform D - - - - 19835342 603.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 42716 1778.00 0.49 0.545 0.153474480661718 Up 0.0638290846651697 CG6688 CG6688 K04506|1|9e-10|65.5|dsi:Dsim_GD14672|E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0019941//modification-dependent protein catabolic process;GO:0032501//multicellular organismal process 3771728 1278.90 45.695 47.76 0.0637665240511774 Up 0.167382115968828 CG33713 CG33713, isoform B K06270|1|5e-12|72.4|dre:445393|protein phosphatase 1 regulatory subunit 12A - GO:0005504//fatty acid binding;GO:0005504//fatty acid binding - 45961 2591.82 96.575 99.545 0.0436990808430404 Up 0.134229295997887 Pep protein on ecdysone puffs, isoform D - GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding GO:0043484//regulation of RNA splicing;GO:0000377;GO:0043484//regulation of RNA splicing;GO:0000377;GO:0043484//regulation of RNA splicing;GO:0000377 3772145 826.00 0.445 0.06 -2.89077093024524 Down 0.253533218861445 CheA86a chemosensory protein A 86a - - - - 41445 1870.00 8.31 8.59 0.0478096543681189 Up 0.0950667018887862 CG3281 CG3281 K09228|1|3e-53|209|dpo:Dpse_GA11270|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19835640 351.00 0.625 0.145 -2.10780328953451 Down 0.271067230220579 36984 986.00 15.035 13.605 -0.144187911324324 Down 0.245674283450007 cyp33 cyclophilin-33 K09564|1|7e-171|600|dme:Dmel_CG4886|peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8] - - - 32207 5381.42 12.545 14.13 0.171648994924767 Up 0.274105138026681 LIMK1 LIM-kinase1, isoform F K05743|1|0.0|1744|dme:Dmel_CG1848|LIM domain kinase 1 [EC:2.7.11.1] - GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0001736//establishment of planar polarity;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0007416//synapse assembly;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0001736//establishment of planar polarity;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0007416//synapse assembly;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0001736//establishment of planar polarity;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0007416//synapse assembly;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0001736//establishment of planar polarity;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0007416//synapse assembly;GO:0007010//cytoskeleton organization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0001736//establishment of planar polarity;GO:0001654//eye development;GO:0006464//cellular protein modification process;GO:0007416//synapse assembly 37588 1262.00 19.035 20.545 0.110132760605394 Up 0.221304979527143 CG3732 CG3732 - - - - 246669 667.24 75.04 47.51 -0.659428621104532 Down 0.664575353321886 Obp57b Odorant-binding protein 57b, isoform B - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 246618 1829.00 7.965 8.595 0.109823277952751 Up 0.164938581429138 Opbp Optix-binding protein K09228|1|1e-45|184|api:100159445|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 32371 3470.54 8.96 10.465 0.224001674198105 Up 0.295139347510236 l(1)G0469 lethal (1) G0469, isoform D - - - - 10178927 783.00 0.455 0.9 0.984058456130979 Up 0.227545898824462 CG42851 CG42851 - - - - 42772 1438.00 1.72 2.955 0.780749565475434 Up 0.364747061154405 CG10177 CG10177 K08805|1|1e-36|154|cin:100180743|doublecortin and CaM kinase-like 1 [EC:2.7.11.1] GO:0031224//intrinsic to membrane GO:0005249//voltage-gated potassium channel activity;GO:0004672//protein kinase activity;GO:0032559 GO:0023033;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process 2768669 1315.00 3.785 3.715 -0.0269310894471356 Down 0.0565975432571655 CG33332 CG33332 - - - - 36409 842.08 395.97 406.13 0.0365504690713666 Up 0.138654074758949 Nacalpha nascent polypeptide associated complex protein alpha subunit, isoform D K03626|1|6e-70|263|dsi:Dsim_GD25812|nascent polypeptide-associated complex subunit alpha GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0044087;GO:0044087;GO:0044087 14462355 2654.00 22.64 23.24 0.0377361105726465 Up 0.112237485140668 43690 4870.89 419.515 637.07 0.602729505710007 Up 0.677585523708889 chp chaoptin, isoform F K05401|1|1e-51|206|dme:Dmel_CG5195|toll-like recepto 3;K04308|5|3e-30|135|bta:520189|leucine-rich repeat-containing G protein-coupled receptor 5 GO:0016020//membrane GO:0005488//binding GO:0016337//cell-cell adhesion;GO:0042051//compound eye photoreceptor development 31425 6220.71 12.985 15.54 0.259140489729303 Up 0.371648395192181 Ptp4E protein tyrosine phosphatase 4E, isoform H K01104|1|0.0|3121|dme:Dmel_CG6899|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043005//neuron projection;GO:0044297//cell body;GO:0044459//plasma membrane part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044459//plasma membrane part GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0007411//axon guidance;GO:0006796//phosphate-containing compound metabolic process;GO:0060541//respiratory system development;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0006796//phosphate-containing compound metabolic process;GO:0060541//respiratory system development;GO:0006464//cellular protein modification process 36136 1138.00 0.28 0.19 -0.559427408614019 Down 0.0934156650376436 mms4 methyl methanesulfonate sensitivity 4 ortholog K10882|1|1e-21|104|tgu:100226337|crossover junction endonuclease EME1 [EC:3.1.22.-] - GO:0016788//hydrolase activity, acting on ester bonds;GO:0003676//nucleic acid binding GO:0044260 38034 3586.77 12.315 13.505 0.133077012010006 Up 0.224574032492405 CG16940 CG16940, isoform C K12585|1|1e-105|385|hmg:100211666|exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] GO:0000178//exosome (RNase complex);GO:0000178//exosome (RNase complex) GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity - 38371 2367.00 0.05 0.075 0.584962500721156 Up 0.0550785893541144 CG14955 CG45067 K06532|1|8e-39|162|dwi:Dwil_GK12310|prominin GO:0031224//intrinsic to membrane - - 40310 4477.60 43.255 52.285 0.273530203592623 Up 0.467936864350812 CG32432 CG32432, isoform B K06233|1|2e-08|62.4|bfo:BRAFLDRAFT_123381|low density lipoprotein-related protein 2 - - - 34808 3010.37 19.56 12.935 -0.596626316267493 Down 0.580603619072778 Ance-3 Ance-3, isoform C K01283|1|0.0|1531|dme:Dmel_CG17988|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0044464//cell part GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 31976 9361.50 24.04 27.69 0.203928157655745 Up 0.362435609562805 nocte no circadian temperature entrainment, isoform D - - - - 37316 440.00 0.1 0.11 0.137503523749935 Up 0.0448421608770308 CG13427 CG13427 - - - - 32576 5918.00 9.135 10.28 0.17036363056639 Up 0.245278034605732 CG42353 CG42353, isoform B - - - - 38575 1173.00 0.305 0.965 1.66171969970519 Up 0.307092854312508 CG12493 CG12493, isoform B K13194|1|6e-08|58.5|aag:AaeL_AAEL002522|double stranded RNA-specific editase 1 [EC:3.5.-.-] GO:0043229//intracellular organelle GO:0003723//RNA binding - 38755 2626.71 21.675 24.595 0.182333061614131 Up 0.330240390965526 tow target of wingless, isoform G - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0008589//regulation of smoothened signaling pathway;GO:0001738//morphogenesis of a polarized epithelium;GO:0008589//regulation of smoothened signaling pathway;GO:0001738//morphogenesis of a polarized epithelium 33576 1390.00 0.055 0.065 0.241008099503795 Up 0.0461960110949676 Sr-CIV scavenger receptor class C, type IV K06724|1|5e-10|65.5|xla:397804|neuropilin 1;K01316|4|3e-09|63.2|dre:100148042|protease, serine, 7 (enterokinase) [EC:3.4.21.9] GO:0016021//integral to membrane GO:0001871;GO:0004888//transmembrane signaling receptor activity GO:0006950//response to stress;GO:0002376//immune system process 10178809 1477.00 0.105 0.155 0.561878887608115 Up 0.0745938449346189 CG42854 CG42854 - - - - 33843 1117.14 5.005 5.525 0.1426043954428 Up 0.164179104477612 CG9107 CG9107, isoform B - - GO:0005488//binding;GO:0005488//binding - 38990 1104.00 3.705 3.17 -0.224990702166427 Down 0.18617091533483 Cpr66D cuticular protein 66D - - GO:0042302//structural constituent of cuticle - 50227 423.00 57.005 60.945 0.096419399366419 Up 0.244386474706115 CG17059 CG17059 - - - - 34203 3110.00 0.29 0.28 -0.0506260730699681 Down 0.0419363360190199 CG9463 CG9463, isoform B K12311|1|0.0|1995|dme:Dmel_CG9463|lysosomal alpha-mannosidase [EC:3.2.1.24] - GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0019318//hexose metabolic process 34980 1814.33 23.115 18.7 -0.305791092460942 Down 0.453473781534804 CG5888 CG5888, isoform B K13023|1|6e-17|89.4|ecb:100069043|carboxypeptidase N regulatory subunit - GO:0005488//binding - 31670 823.64 1.385 2.7 0.963073431001643 Up 0.387993660018492 CG15034 CG15034, isoform B - - - - 39092 788.00 2.395 0.245 -3.28917200162097 Down 0.557951393475102 CG33926 CG33926, isoform B K06793|1|5e-12|71.2|oaa:100080845|chondroitin sulfate proteoglycan 2 (versican);K04877|5|1e-11|69.7|oaa:100074063|potassium voltage-gated channel Shaker-related subfamily A member 4 - - - 19835933 878.00 1.6 1.615 0.0134622598065624 Up 0.041044776119403 34299 1551.00 0.13 0.21 0.691877704637668 Up 0.0911042134460441 ppk11 pickpocket 11 K04832|1|6e-18|92.4|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0007424//open tracheal system development;GO:0050909//sensory perception of taste;GO:0030001//metal ion transport 32341 1428.53 226.13 161.725 -0.483609690129676 Down 0.633932109364681 CtsB1 cathepsin B1, isoform C K01363|1|0.0|704|dme:Dmel_CG10992|cathepsin B [EC:3.4.22.1] - GO:0004175//endopeptidase activity GO:0019222//regulation of metabolic process;GO:0019538//protein metabolic process;GO:0048102//autophagic cell death 32141 1980.58 7.685 9.255 0.268187730179803 Up 0.320036983225466 CG10347 CG10347, isoform B - - - - 3772463 2572.00 0.165 0.125 -0.400537929583729 Down 0.0673292827895919 317826 792.00 11.32 13.54 0.258353780743114 Up 0.35669000132083 CG32022 CG32022, isoform B - GO:0031224//intrinsic to membrane - - 19835322 2492.00 9.375 10.58 0.17444903184342 Up 0.250759476951526 37147 1777.58 46.26 44.65 -0.0511050906276054 Down 0.145819574692907 SP2637 SP2637, isoform D K01463|1|1e-65|250|bfo:BRAFLDRAFT_200206| [EC:3.5.1.-] - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - 37207 2332.00 0.055 0.27 2.29545588352617 Up 0.176859067494386 CG7229 CG7229 K11721|1|2e-23|111|ame:551826|bromodomain-containing protein 3;K11724|3|5e-23|109|hsa:676|bromodomain testis-specific protein - - - 3771779 1322.00 81.265 41.745 -0.961030722755088 Down 0.713313961167613 CG18003 CG18003 K11517|1|0.0|664|dme:Dmel_CG18003|(S)-2-hydroxy-acid oxidase [EC:1.1.3.15] - GO:0000166//nucleotide binding;GO:0003824//catalytic activity GO:0008152//metabolic process 34753 6023.00 2.72 2.905 0.0949315121541896 Up 0.0906419231277242 CG7099 CG7099 - - - - 38235 805.28 16.055 13.51 -0.248994990400085 Down 0.365308413683793 JTBR JTBR, isoform C - GO:0031224//intrinsic to membrane - - 38313 1875.03 28.115 22.635 -0.312784740292965 Down 0.470941751419892 CG1146 CG1146, isoform D - - - - 33562 2973.00 9.15 10.93 0.2564497525005 Up 0.331164971602166 Cog3 Cog3 - GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0044431//Golgi apparatus part GO:0022892 GO:0050658//RNA transport;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 36640 477.00 207.56 180.755 -0.19949288578837 Down 0.423061682736759 CG12859 CG12859 K03960|1|9e-60|228|dme:Dmel_CG12859|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity - 37175 669.00 46.605 47.315 0.0218128831381258 Up 0.0862171443666623 CG15083 CG15083 - - - - 38207 1252.34 7.005 6.775 -0.0481641041895843 Down 0.0874719323735306 CG7974 CG7974, isoform B - - - - 5740498 1091.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG34202 CG34202 - - - - 38252 2478.42 27.14 30.365 0.161988648431219 Up 0.316866992471272 CG1887 CG1887, isoform G K12384|1|8e-55|215|mmu:12492|lysosome membrane protein 2 GO:0016021//integral to membrane GO:0004871//signal transducer activity GO:0006950//response to stress;GO:0009987//cellular process 43554 1514.56 27.53 30.64 0.154411687329396 Up 0.305441817461366 CG7903 CG7903, isoform B K13189|1|8e-11|68.6|dre:402858|RNA-binding protein 14;K13187|3|5e-10|65.9|tca:659335|RNA-binding protein 4 - GO:0005488//binding - 19835372 2151.00 0.325 0.085 -1.93490497177812 Down 0.18095363888522 34158 726.63 5.905 7.99 0.436258443530819 Up 0.406155065381059 Rcd4 reduction in Cnn dots 4, isoform B - - - - 50220 329.00 5.555 8.975 0.692125027321322 Up 0.516015057456082 CG12853 CG12853 - - - - 39365 4623.00 5.925 8.26 0.479326627633824 Up 0.429929996037512 Grip163 Grip163 K01769|1|1e-52|209|tca:657050|guanylate cyclase, other [EC:4.6.1.2] GO:0015630//microtubule cytoskeleton;GO:0044430//cytoskeletal part - GO:0007010//cytoskeleton organization 34614 1033.00 41.885 53.185 0.344585739936078 Up 0.530180953638885 CG6746 CG6746 K10703|1|1e-134|479|dme:Dmel_CG6746|3-hydroxy acyl-CoA dehydratase [EC:4.2.1.-] - - - 43197 7490.00 4.275 4.425 0.0497530351970997 Up 0.0745938449346189 CG6490 plum, isoform E K06763|1|3e-14|82.4|mcc:700826|contactin 5;K06765|4|4e-14|82.0|xla:378529|deleted in colorectal carcinoma;K06759|5|4e-14|82.0|mmu:12805|contactin 1 - - - 53513 1617.00 0.145 0.335 1.2081081953302 Up 0.150112270505878 Ugt36Ba Ugt36Ba, isoform B K00699|1|0.0|925|dme:Dmel_CG13270|glucuronosyltransferase [EC:2.4.1.17] - GO:0008194//UDP-glycosyltransferase activity - 32350 2786.00 5.095 4.115 -0.308189715744188 Down 0.273807951393475 CG11092 nucleoporin 93kD-1 - GO:0005635//nuclear envelope - GO:0051234//establishment of localization 33223 2592.00 8.63 9 0.0605644420380821 Up 0.110619469026549 MED15 mediator complex subunit 15 - GO:0043234//protein complex;GO:0044464//cell part GO:0016251//general RNA polymerase II transcription factor activity;GO:0005515//protein binding GO:0006355//regulation of transcription, DNA-dependent 41181 9077.00 23.09 22.705 -0.0242581363497813 Down 0.0802403909655263 hyd hyperplastic discs, isoform B K10593|1|0.0|4891|dme:Dmel_CG9484|E3 ubiquitin-protein ligase EDD1 [EC:6.3.2.19] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity GO:0043412//macromolecule modification 40946 1309.00 152.71 139.09 -0.134775838330013 Down 0.315678245938449 CG2767 CG2767 K00002|1|5e-176|617|dme:Dmel_CG2767|alcohol dehydrogenase (NADP+) [EC:1.1.1.2];K00011|2|2e-63|243|tca:657943|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity GO:0008152//metabolic process 31443 1108.00 3.57 4.705 0.398270648699437 Up 0.310527010962885 TrxT thioredoxin T, isoform B K03671|1|4e-31|135|dgr:Dgri_GH10676|thioredoxin 1 GO:0043231//intracellular membrane-bounded organelle GO:0015036//disulfide oxidoreductase activity GO:0010259//multicellular organismal aging;GO:0018904;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis 44679 2392.19 36.345 31.05 -0.227163637064659 Down 0.408664641394796 ergic53 ergic53, isoform B K10080|1|0.0|941|dme:Dmel_CG6822|lectin, mannose-binding 1 GO:0044464//cell part;GO:0044464//cell part - - 38884 2378.00 0.53 0.565 0.0922585078519884 Up 0.0504226654338925 exex extra-extra K08025|1|5e-24|113|dre:406206|homeobox protein HB9 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007154//cell communication;GO:0030182//neuron differentiation 43682 4066.00 32.005 35.76 0.160049427917643 Up 0.324296658301413 Gycbeta100B guanylyl cyclase beta-subunit at 100B K12319|1|0.0|1352|dme:Dmel_CG1470|guanylate cyclase soluble subunit beta [EC:4.6.1.2] GO:0043234//protein complex GO:0009975//cyclase activity;GO:0005506//iron ion binding;GO:0016829//lyase activity GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process 246567 1505.51 0.365 0.575 0.655665492064358 Up 0.140536256769251 hubl hug-bell, isoform B - - - - 261634 835.69 16.285 18.475 0.18203064463761 Up 0.308644828952582 CG31051 CG31051, isoform B - - - - 12798487 612.00 0.27 1.94 2.84502534002366 Up 0.499801875577863 32826 1382.00 1.785 2.875 0.687637881802638 Up 0.334896314885748 CG32548 CG32548, isoform C - - - - 2768938 1594.00 8.07 2.575 -1.6479962412072 Down 0.645324263637564 CG33281 CG33281 K08145|1|4e-41|169|nve:NEMVE_v1g204860|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane GO:0051119//sugar transmembrane transporter activity GO:0006810//transport 31829 3077.58 2.36 2.205 -0.0980082038043206 Down 0.0833113195086514 CG15365 CG15365, isoform C - GO:0044464//cell part - - 19836125 1316.00 3.41 3.335 -0.0320849778395876 Down 0.0585787874785365 8674074 376.00 0.805 1.38 0.777607578663552 Up 0.250495311055343 CG42537 CG42537 K06238|1|3e-06|49.7|ecb:100066356|collagen, type VI, alpha - GO:0004866//endopeptidase inhibitor activity - 317898 1442.00 0.97 1.17 0.270451877396277 Up 0.116959450534936 CG32182 CG32182 - - - - 31483 584.32 848.96 775.745 -0.130114087666407 Down 0.324891031567825 RpL35 ribosomal protein L35, isoform C K02918|1|1e-51|202|dme:Dmel_CG4111|large subunit ribosomal protein L35e - - - 19834872 455.00 0.095 0.105 0.144389909335175 Up 0.0448421608770308 41863 1784.82 61.69 69.2 0.165735391593563 Up 0.361511028926166 CG6218 CG6218, isoform B K00884|1|0.0|663|dme:Dmel_CG6218|N-acetylglucosamine kinase [EC:2.7.1.59] - - - 42312 2550.88 1.345 0.49 -1.45675251844142 Down 0.341797648923524 CG14280 CG14280, isoform B - - - - 19836058 1297.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 38124 1212.00 191.54 63.355 -1.59611531990776 Down 0.772024831594241 CG9119 CG9119 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity - 40317 913.00 2.72 3.65 0.42428981251704 Up 0.284803856822084 CG11037 CG11037 K01312|1|1e-30|133|dme:Dmel_CG12387|trypsin [EC:3.4.21.4];K09635|3|6e-29|127|dre:777630|transmembrane protease, serine 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42919 2371.52 34.245 35.705 0.0602327579511722 Up 0.160315678245938 nAcRalpha-96Ab nicotinic acetylcholine receptor alpha2, isoform B K05312|1|0.0|1073|dsi:Dsim_GD21103|nicotinic acetylcholine receptor, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport 46015 6984.50 68.66 79.21 0.206212719975539 Up 0.418075551446308 tutl turtle, isoform I K06766|1|6e-42|174|oaa:100076606|neogenin - - GO:0008344//adult locomotory behavior;GO:0016198//axon choice point recognition;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0008344//adult locomotory behavior;GO:0016198//axon choice point recognition;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0008344//adult locomotory behavior;GO:0016198//axon choice point recognition;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0008344//adult locomotory behavior;GO:0016198//axon choice point recognition;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0008344//adult locomotory behavior;GO:0016198//axon choice point recognition;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0008344//adult locomotory behavior;GO:0016198//axon choice point recognition;GO:0010769//regulation of cell morphogenesis involved in differentiation 33287 1030.00 8.285 8.925 0.10735047169501 Up 0.1658961828028 CG14340 CG14340 - - - - 34780 1821.00 26.365 24.025 -0.13408756571872 Down 0.268788799366002 p38b p38b MAP kinase K04441|1|0.0|739|dme:Dmel_CG7393|p38 MAP kinase [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle GO:0004707//MAP kinase activity;GO:0032559 GO:0007472//wing disc morphogenesis;GO:0002759//regulation of antimicrobial humoral response;GO:0007243//intracellular protein kinase cascade;GO:0030509//BMP signaling pathway;GO:0006970//response to osmotic stress;GO:0031347//regulation of defense response;GO:0002251;GO:0006464//cellular protein modification process 44324 936.19 197.955 219.7 0.150362361958203 Up 0.351241579712059 Dms myosuppressin, isoform C - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0008016//regulation of heart contraction 35758 3344.39 40 49.835 0.317159328453001 Up 0.512679963016775 CG8726 CG8726, isoform C K11322|1|2e-123|433|tca:660832|enhancer of polycomb-like protein;K08861|3|2e-06|55.8|dre:565576|polo-like kinase 2 [EC:2.7.11.21] - GO:0005543//phospholipid binding;GO:0016301//kinase activity;GO:0032559;GO:0005543//phospholipid binding;GO:0016301//kinase activity;GO:0032559;GO:0005543//phospholipid binding;GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 39038 1945.00 0.095 0.27 1.50695998871988 Up 0.149914146083741 Doc2 Dorsocross2 K10180|1|3e-114|412|dpo:Dpse_GA18682|T-box protein 6 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009792//embryo development ending in birth or egg hatching;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007507//heart development 44801 1555.98 129.67 145.915 0.170283458026809 Up 0.377889314489499 bsk basket, isoform F K04440|1|0.0|752|dya:Dyak_GE26274|c-Jun N-terminal kinase [EC:2.7.11.24] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0016909//SAP kinase activity;GO:0032559;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0016909//SAP kinase activity;GO:0032559;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0016909//SAP kinase activity;GO:0032559 GO:0007166//cell surface receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation;GO:0006582//melanin metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0042742//defense response to bacterium;GO:0005977//glycogen metabolic process;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0007391//dorsal closure;GO:0006468//protein phosphorylation;GO:0044319//wound healing, spreading of cells;GO:0006935//chemotaxis;GO:0048858//cell projection morphogenesis;GO:0048588//developmental cell growth;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation;GO:0006582//melanin metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0042742//defense response to bacterium;GO:0005977//glycogen metabolic process;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0007391//dorsal closure;GO:0006468//protein phosphorylation;GO:0044319//wound healing, spreading of cells;GO:0006935//chemotaxis;GO:0048858//cell projection morphogenesis;GO:0048588//developmental cell growth;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation;GO:0006582//melanin metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0042742//defense response to bacterium;GO:0005977//glycogen metabolic process;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0007391//dorsal closure;GO:0006468//protein phosphorylation;GO:0044319//wound healing, spreading of cells;GO:0006935//chemotaxis;GO:0048858//cell projection morphogenesis;GO:0048588//developmental cell growth;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade 33816 438.29 5.755 6.715 0.222571471295212 Up 0.245344076079778 Acp26Ab accessory gland protein 26Ab, isoform C - GO:0044421//extracellular region part;GO:0044421//extracellular region part - GO:0033057;GO:0007618//mating;GO:0033057;GO:0007618//mating 36517 2104.00 1.215 1.25 0.0409717810563064 Up 0.050752872804121 CG6209 CG6209 - GO:0005681//spliceosomal complex - - 31144 2543.00 27.835 27.875 0.00207172182919616 Up 0.0434552899220711 Vps26 vacuolar protein sorting 26 - - - - 31236 936.28 8.505 10.175 0.258645653490224 Up 0.323140932505614 CG13759 CG13759, isoform D K00669|1|6e-19|94.7|dme:Dmel_CG3318|arylalkylamine N-acetyltransferase [EC:2.3.1.87] - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 14462465 493.00 2.375 1.925 -0.303069067636047 Down 0.184552899220711 49228 2014.06 96.845 96.175 -0.0100156414835815 Down 0.0677585523708889 mod(mdg4) modifier of mdg4, isoform Z K09237|1|2e-24|114|dwi:Dwil_GK12114|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 34505 2854.00 37.105 36.46 -0.0252990456621546 Down 0.100746268656716 Stam signal transducing adaptor molecule K04705|1|0.0|968|dme:Dmel_CG6521|signal transducing adaptor molecule - GO:0008268 GO:0001505//regulation of neurotransmitter levels;GO:0010627//regulation of intracellular protein kinase cascade;GO:0006897//endocytosis;GO:0007424//open tracheal system development 44046 414.53 556.005 540.28 -0.0413905792708598 Down 0.139644696869634 sun stunted, isoform B K02135|1|9e-24|110|dya:Dyak_GE16014|F-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process;GO:0006950//response to stress;GO:0006818//hydrogen transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process;GO:0006950//response to stress 47457 2076.00 26.995 30.705 0.18578138629531 Up 0.354477611940299 ytr yantar, isoform B K12846|1|8e-34|145|dya:Dyak_GE11524|U4/U6.U5 tri-snRNP-associated protein 3 GO:0005681//spliceosomal complex - GO:0000377;GO:0048534 40693 4452.32 20.98 22.25 0.0847906581638549 Up 0.180920618148197 MTA1-like MTA1-like, isoform D K11660|1|0.0|1507|dme:Dmel_CG2244|metastasis-associated protein MTA GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006909//phagocytosis;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0006351//transcription, DNA-dependent 41574 1667.00 3.635 17.065 2.23101314517927 Up 0.737121912561088 CG5999 CG5999 K00699|1|0.0|908|dme:Dmel_CG5999|glucuronosyltransferase [EC:2.4.1.17] - - - 37681 1410.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 LS2 large subunit 2 K12837|1|2e-116|419|tca:663317|splicing factor U2AF 65 kDa subunit GO:0030532//small nuclear ribonucleoprotein complex GO:0003723//RNA binding GO:0006396//RNA processing 42413 3528.53 13.675 13.105 -0.0614234793515014 Down 0.128945978074231 CG4360 CG4360, isoform B K09228|1|1e-60|235|cfa:474650|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0005488//binding - 33510 1199.76 22.36 38.015 0.765648602890919 Up 0.663353586052041 CG17224 CG17224, isoform D K00757|1|3e-163|574|dme:Dmel_CG17224|uridine phosphorylase [EC:2.4.2.3] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 38291 2204.00 14.33 13.62 -0.0733119062500746 Down 0.14562145027077 ecd ecdysoneless - - - GO:0008205//ecdysone metabolic process;GO:0051707//response to other organism;GO:0006996//organelle organization;GO:0018988;GO:0002164//larval development;GO:0001745//compound eye morphogenesis;GO:0040003//chitin-based cuticle development;GO:0007292//female gamete generation;GO:0048534;GO:0001700//embryonic development via the syncytial blastoderm 42132 621.00 1.43 2.955 1.04714298339914 Up 0.420453044511954 Atg8b Autophagy-specific gene 8b K08341|1|2e-66|251|dme:Dmel_CG12334|GABA(A) receptor-associated protein (autophagy-related protein 8) - - - 326237 1920.84 1093.735 799.165 -0.452697925506973 Down 0.630266807555145 Ubi-p5E Ubiquitin-5E, isoform B K08770|1|0.0|1036|dan:Dana_GF20300|ubiquitin C GO:0030529//ribonucleoprotein complex;GO:0015630//microtubule cytoskeleton GO:0005488//binding GO:0019941//modification-dependent protein catabolic process;GO:0043412//macromolecule modification 33535 1273.00 2.44 2.26 -0.110558375147699 Down 0.092458063663981 CG44002 CG44002 - - - - 39990 2103.86 4.79 5.11 0.093297635201441 Up 0.114515915995245 CG5535 CG5535, isoform C K13864|1|5e-145|514|gga:422730|solute carrier family 7 (cationic amino acid transporter), member 2;K13865|5|9e-142|504|xla:380020|solute carrier family 7 (cationic amino acid transporter), member 3 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity GO:0006865//amino acid transport;GO:0044238//primary metabolic process;GO:0006865//amino acid transport;GO:0044238//primary metabolic process 43174 3970.20 0.515 0.61 0.244236810379668 Up 0.0845330867784969 dys dysfusion, isoform D K08268|1|1e-14|82.8|rno:29560|hypoxia-inducible factor 1 alpha;K09095|5|3e-13|78.6|xtr:448117|hypoxia-inducible factor 2 alpha GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551 14462763 537.00 0.08 0.09 0.169925001442312 Up 0.045667679302602 19835515 319.00 1.82 1.83 0.00790519808534616 Up 0.041044776119403 34413 3485.52 22.165 22.425 0.0168246226413589 Up 0.0738343679830934 da daughterless, isoform C K09063|1|0.0|839|dme:Dmel_CG5102|transcription factor 3/4/12 - GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0001745//compound eye morphogenesis;GO:0007292//female gamete generation;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0003006//developmental process involved in reproduction;GO:0006350;GO:0010557//positive regulation of macromolecule biosynthetic process 37579 4533.40 20.155 23.57 0.225813975399088 Up 0.379540351340642 CG4294 CG4294, isoform C K12478|1|7e-07|57.4|cfa:475424|early endosome antigen 1 GO:0044424//intracellular part GO:0046872//metal ion binding GO:0006793//phosphorus metabolic process 45380 3144.39 35.3 35.51 0.00855717686242933 Up 0.0612864879144102 spin spinster, isoform E K06258|1|1e-06|55.8|oaa:100078882|MFS transporter, VNT family, synaptic vesicle glycoprotein 2;K08171|2|4e-06|54.3|gga:419789|MFS transporter, OPA family, solute carrier family 37 (glycerol-6-phosphate transporter), member 4 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane - GO:0002165//instar larval or pupal development;GO:0048638//regulation of developmental growth;GO:0060180//female mating behavior;GO:0007041//lysosomal transport;GO:0042981//regulation of apoptotic process;GO:0007292//female gamete generation;GO:0006897//endocytosis;GO:0002165//instar larval or pupal development;GO:0048638//regulation of developmental growth;GO:0060180//female mating behavior;GO:0007041//lysosomal transport;GO:0042981//regulation of apoptotic process;GO:0007292//female gamete generation;GO:0006897//endocytosis;GO:0002165//instar larval or pupal development;GO:0048638//regulation of developmental growth;GO:0060180//female mating behavior;GO:0007041//lysosomal transport;GO:0042981//regulation of apoptotic process;GO:0007292//female gamete generation;GO:0006897//endocytosis;GO:0002165//instar larval or pupal development;GO:0048638//regulation of developmental growth;GO:0060180//female mating behavior;GO:0007041//lysosomal transport;GO:0042981//regulation of apoptotic process;GO:0007292//female gamete generation;GO:0006897//endocytosis;GO:0002165//instar larval or pupal development;GO:0048638//regulation of developmental growth;GO:0060180//female mating behavior;GO:0007041//lysosomal transport;GO:0042981//regulation of apoptotic process;GO:0007292//female gamete generation;GO:0006897//endocytosis 41397 4250.00 4.72 4.975 0.0759096660691697 Up 0.0990952318055739 CG14712 CG14712 - GO:0005622//intracellular GO:0005488//binding - 19835275 273.00 0.335 0.195 -0.780686971595524 Down 0.118841632545238 35424 5348.72 46.39 55.935 0.269937451644961 Up 0.470446440364549 CG31619 CG31619, isoform G K08624|1|9e-49|196|ecb:100049887|a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 14462375 2248.00 22.385 16.925 -0.403376484441185 Down 0.511887465328226 33336 1298.00 0.12 0.535 2.15650448567999 Up 0.252443534539691 Or22b odorant receptor 22b K08471|1|0.0|804|dme:Dmel_CG4231|gustatory receptor GO:0043005//neuron projection GO:0005488//binding;GO:0004930//G-protein coupled receptor activity GO:0007606//sensory perception of chemical stimulus 39879 1247.18 23.305 16.365 -0.510025910494181 Down 0.565447100779289 nudC nudC, isoform B - GO:0015630//microtubule cytoskeleton - GO:0007292//female gamete generation;GO:0040023//establishment of nucleus localization 33599 4083.49 26.47 31.725 0.26126196923307 Up 0.431548012151631 Shaw shaker cognate w, isoform E K05320|1|0.0|1031|dme:Dmel_CG2822|potassium voltage-gated channel Shaw-related subfamily C, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005267//potassium channel activity GO:0030001//metal ion transport;GO:0007610//behavior;GO:0030001//metal ion transport;GO:0007610//behavior;GO:0030001//metal ion transport;GO:0007610//behavior 44668 729.00 5.915 4.805 -0.299841737566038 Down 0.287775723154141 SmD1 small ribonucleoprotein particle protein SmD1 K11087|1|6e-40|161|dya:Dyak_GE20102|small nuclear ribonucleoprotein D1 GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0000398//mRNA splicing, via spliceosome 36667 3904.00 16.255 13.83 -0.233082399539862 Down 0.350746268656716 Cyp317a1 Cyp317a1, isoform C K00517|1|0.0|978|dme:Dmel_CG17453| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 42853 3924.00 16.04 14.895 -0.10684601820539 Down 0.204497424382512 SMC1 SMC1 K06636|1|0.0|2262|dme:Dmel_CG6057|structural maintenance of chromosome 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin GO:0032559 GO:0006996//organelle organization;GO:0007420//brain development;GO:0007059//chromosome segregation;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0010467//gene expression 19835491 488.00 0.09 0.1 0.15200309344505 Up 0.045238409721305 34704 415.52 194.245 346.115 0.833374003512338 Up 0.715295205388984 CG9928 CG9928, isoform B - - - - 19836173 294.00 0.01 20.985 11.0351427478859 Up 0.951888786157707 31858 3399.00 24.59 27.165 0.143677312075242 Up 0.284902919033153 su(r) suppressor of rudimentary K00207|1|0.0|2020|dme:Dmel_CG2194|dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] GO:0044424//intracellular part GO:0004152//dihydroorotate dehydrogenase activity;GO:0051540;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0009174 39179 1752.00 1.355 0.055 -4.62271742271657 Down 0.505481442345793 CG42825 CG42825 K07191|1|5e-07|56.2|cfa:403673|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4;K08145|3|2e-06|54.3|mdo:100020584|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8;K07593|5|7e-06|52.4|mdo:100010342|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2 GO:0016020//membrane - GO:0006810//transport 35340 4315.13 11.86 13.425 0.178818078326771 Up 0.279586580372474 dia diaphanous, isoform E K05740|1|5e-99|363|hsa:1729|diaphanous 1 GO:0032991//macromolecular complex;GO:0070161;GO:0015629//actin cytoskeleton;GO:0032155;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0070161;GO:0015629//actin cytoskeleton;GO:0032155;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding GO:0000278//mitotic cell cycle;GO:0008360//regulation of cell shape;GO:0007051//spindle organization;GO:0003006//developmental process involved in reproduction;GO:0003382//epithelial cell morphogenesis;GO:0015031//protein transport;GO:0045185//maintenance of protein location;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0060541//respiratory system development;GO:0000278//mitotic cell cycle;GO:0008360//regulation of cell shape;GO:0007051//spindle organization;GO:0003006//developmental process involved in reproduction;GO:0003382//epithelial cell morphogenesis;GO:0015031//protein transport;GO:0045185//maintenance of protein location;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0033206//cytokinesis after meiosis;GO:0060541//respiratory system development 41190 1432.00 0.825 1.06 0.361598240317384 Up 0.138026680755514 Rpt3R regulatory particle triple-A ATPase 3-related, isoform D K03063|1|0.0|797|dme:Dmel_CG9475|26S proteasome regulatory subunit T3 GO:0043073//germ cell nucleus;GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0033554//cellular response to stress;GO:0044267//cellular protein metabolic process 36924 5147.20 12.955 12.985 0.00333699849831295 Up 0.0427618544445912 CG30460 CG30460, isoform I - - - - 39668 620.00 0.455 0.295 -0.625151590836855 Down 0.122242768458592 CG7276 CG7276 K11806|1|1e-80|298|dsi:Dsim_GD14543|WD repeat and SOF domain-containing protein 1;K10420|2|8e-06|50.1|cin:723808|dynein light chain Tctex-type 1 - GO:0016887//ATPase activity GO:0007017//microtubule-based process 318044 1018.00 0.31 0.045 -2.78427130894456 Down 0.200931184784044 Tengl2 testis EndoG-Like 2 K01173|1|5e-70|264|dme:Dmel_CG8862|endonuclease [EC:3.1.30.-] GO:0043231//intracellular membrane-bounded organelle GO:0004519//endonuclease activity;GO:0043169//cation binding - 40009 4018.00 16.37 8.02 -1.02938018001923 Down 0.65153216219786 W wrinkled, isoform B - GO:0031982//vesicle;GO:0044425//membrane part GO:0042626//ATPase activity, coupled to transmembrane movement of substances GO:0006726//eye pigment biosynthetic process;GO:0009639//response to red or far red light;GO:0007611//learning or memory;GO:0006576//cellular biogenic amine metabolic process;GO:0009648//photoperiodism;GO:0040008//regulation of growth;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035071//salivary gland cell autophagic cell death;GO:0007619//courtship behavior;GO:0012502//induction of programmed cell death;GO:0032446//protein modification by small protein conjugation;GO:0006508//proteolysis;GO:0070729;GO:0046666//retinal cell programmed cell death;GO:0060541//respiratory system development;GO:0042981//regulation of apoptotic process 31887 5653.74 11.865 14.855 0.324236504641467 Up 0.421839915466913 CG34449 CG34449, isoform G K09409|1|4e-06|54.3|aga:AgaP_AGAP000569|forkhead box protein P GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding;GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding - 40825 765.00 4.3 20.96 2.28523015194799 Up 0.750066041474046 Ccp84Aa Ccp84Aa - - GO:0042302//structural constituent of cuticle - 42183 1093.00 10.015 11.155 0.155528092431433 Up 0.239103156782459 CG7993 putative nucleolar protein 3 - - - - 59260 2089.00 6.495 4.3 -0.594992865858421 Down 0.438416325452384 tatl trimethylguanosine synthase 1 ortholog - GO:0044427//chromosomal part GO:0016741 GO:0009451//RNA modification;GO:0006396//RNA processing;GO:0000723//telomere maintenance 42601 6527.78 11.425 9.69 -0.237625594530351 Down 0.319541672170123 SKIP shal K[+] channel interacting protein, isoform J K04438|1|2e-08|62.8|xtr:448023|proto-oncogene C-crk - - - 44747 3979.00 25.035 21.2 -0.239882190633193 Down 0.394828952582222 msk moleskin - GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0008565//protein transporter activity;GO:0017016//Ras GTPase binding GO:0001708//cell fate specification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0000060//protein import into nucleus, translocation;GO:0042051//compound eye photoreceptor development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0043066//negative regulation of apoptotic process 14462824 413.37 1.13 1.82 0.687615677783509 Up 0.267534011359134 31816 2802.29 151.395 183.91 0.280682368201787 Up 0.508849557522124 Moe moesin, isoform M K05762|1|0.0|655|bfo:BRAFLDRAFT_219565|radixin;K05763|2|0.0|653|ecb:100065348|moesin GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development;GO:0033036;GO:0048729//tissue morphogenesis;GO:0007315//pole plasm assembly;GO:0016056//rhodopsin mediated signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0007635//chemosensory behavior;GO:0030036//actin cytoskeleton organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044091//membrane biogenesis;GO:0042051//compound eye photoreceptor development 37574 765.00 2.435 3.595 0.562069998356956 Up 0.333773609826971 CG11362 CG11362 - - - - 42188 360.00 125.37 141.38 0.173385882516016 Up 0.377790252278431 CG18598 CG18598 - - - - 44750 2203.00 14.825 16.53 0.157054619858948 Up 0.273973055078589 Ady43A Ady43A K00856|1|0.0|700|dme:Dmel_CG1851|adenosine kinase [EC:2.7.1.20] - GO:0019206//nucleoside kinase activity GO:0043101//purine-containing compound salvage 43038 1894.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 bam bag of marbles - GO:0043232;GO:0044444//cytoplasmic part GO:0030371//translation repressor activity GO:0006996//organelle organization;GO:0007293//germarium-derived egg chamber formation;GO:0006903//vesicle targeting;GO:0007126//meiosis;GO:0048136;GO:0042078//germ-line stem cell division;GO:0045165//cell fate commitment 34112 9220.90 13.97 13.59 -0.039786564642072 Down 0.100250957601374 Piezo piezo, isoform N - - - - 36391 2079.88 26.85 8.87 -1.59791607857171 Down 0.729758288204993 CG8785 CG8785, isoform B - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity - 32101 640.00 45.595 42.085 -0.115569508134444 Down 0.271826707172104 CG11699 CG11699 - - - - 42583 1800.00 3.5 4.22 0.269888076874856 Up 0.226225069343548 CG17843 CG17843 K10758|1|1e-101|370|dme:Dmel_CG31413|thiol oxidase [EC:1.8.3.2] - GO:0016972//thiol oxidase activity GO:0008152//metabolic process;GO:0019725//cellular homeostasis 19834812 390.00 0.125 0.15 0.263034405833794 Up 0.0530973451327434 38688 936.00 4.205 12.43 1.56364859079734 Up 0.679302602034077 CG10472 CG10472 K01310|1|3e-65|248|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|5|6e-45|181|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 50123 477.00 16.055 12.455 -0.366297643484933 Down 0.460507198520671 CG15456 CG15456, isoform B K07401|1|7e-48|189|dse:Dsec_GM22669|selenoprotein W-related protein - GO:0005488//binding GO:0019725//cellular homeostasis 50432 331.00 0.64 0.3 -1.09310940439148 Down 0.203803988905032 Peritrophin-15b Peritrophin-15b, isoform C - GO:0044421//extracellular region part GO:0030247//polysaccharide binding GO:0006022 41673 2482.68 13.39 12.155 -0.139606067295582 Down 0.234348170651169 lkb1 lkb1, isoform J K07298|1|0.0|974|dme:Dmel_CG9374|serine/threonine-protein kinase 11 [EC:2.7.11.9] GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0016055//Wnt receptor signaling pathway;GO:0045165//cell fate commitment;GO:0043408//regulation of MAPK cascade;GO:0008285//negative regulation of cell proliferation;GO:0019094//pole plasm mRNA localization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0030707//ovarian follicle cell development;GO:0022402//cell cycle process;GO:0006915//apoptotic process;GO:0006464//cellular protein modification process 19835326 726.00 0.115 0.135 0.231325546106456 Up 0.0521727644961036 19836116 3359.00 0.035 0.15 2.09953567355091 Up 0.1267335886937 - CG45064 - - - - 36592 3614.74 27.48 23.81 -0.206814383547766 Down 0.370789856029587 Shroom shroom, isoform H - GO:0043296//apical junction complex;GO:0015629//actin cytoskeleton;GO:0043296//apical junction complex;GO:0015629//actin cytoskeleton;GO:0043296//apical junction complex;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0048870//cell motility;GO:0048753//pigment granule organization;GO:0048870//cell motility;GO:0048753//pigment granule organization;GO:0048870//cell motility;GO:0048753//pigment granule organization 41169 1177.00 0.265 0.345 0.38060400221497 Up 0.0866464139479593 Fst frost - - - GO:0006950//response to stress 19834804 1267.00 6.125 7.05 0.202913413396223 Up 0.235569937921014 19835478 903.00 0.135 0.1 -0.432959407276106 Down 0.0678576145819575 43548 1095.00 15.22 14.31 -0.0889446867768777 Down 0.174250429269581 CG42557 CG42557 - - - - 32629 2842.31 14.715 16.88 0.19802736176679 Up 0.322084268920882 CG9784 CG9784, isoform C K01106|1|0.0|997|dme:Dmel_CG9784|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] GO:0044464//cell part GO:0004437//inositol or phosphatidylinositol phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0048523//negative regulation of cellular process;GO:0051129 14462799 803.00 1.95 2.585 0.406690156565324 Up 0.235536917183992 CG43731 CG43731 - - - - 41046 7123.84 4.925 5.635 0.194291885828482 Up 0.206115440496632 CG11768 CG11768, isoform C - - - - 41147 1370.00 11.465 11.105 -0.0460269620338127 Down 0.104411570466253 RnpS1 RNA-binding protein S1 K12883|1|1e-07|58.2|isc:IscW_ISCW017479|nuclear cap-binding protein subunit 2;K12838|2|2e-06|53.9|tad:TRIADDRAFT_64128|poly(U)-binding-splicing factor PUF60;K12891|3|7e-06|52.0|smm:Smp_113620.3|splicing factor, arginine/serine-rich 2 GO:0016604//nuclear body GO:0003723//RNA binding GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006396//RNA processing 46066 1053.62 10.865 10.745 -0.0160226917534993 Down 0.0611544049663188 l(2)05714 lethal (2) 05714, isoform C - - - - 41589 2910.91 8.56 11.74 0.455749706708905 Up 0.471106855105006 CG7381 CG7381, isoform F K00924|1|1e-09|66.2|cel:D1044.3| [EC:2.7.1.-];K06826|2|2e-09|65.1|tca:661043|nidogen (entactin);K08023|3|6e-07|57.0|xla:398322|latent transforming growth factor beta binding protein - - - 34275 2291.30 14.14 13.485 -0.0684265985737954 Down 0.141956148461234 CG3838 CG3838, isoform B - - - - 34968 1996.00 0.5 0.695 0.475084882948783 Up 0.128978998811253 fzy fizzy K03363|1|0.0|1036|dme:Dmel_CG4274|cell division cycle 20, cofactor of APC complex GO:0005815//microtubule organizing center;GO:0000775//chromosome, centromeric region - GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0006909//phagocytosis;GO:0007143//female meiosis;GO:0019827//stem cell maintenance;GO:0007346//regulation of mitotic cell cycle 39988 1921.98 324.22 324.09 -0.000578582338169357 Down 0.0457337207766477 CG7430 CG7430, isoform B K00382|1|0.0|994|dme:Dmel_CG7430|dihydrolipoamide dehydrogenase [EC:1.8.1.4] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0030554//adenyl nucleotide binding;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor GO:0000273;GO:0006544//glycine metabolic process;GO:0019725//cellular homeostasis;GO:0009060//aerobic respiration 48531 1892.00 0.515 0.825 0.679821687062597 Up 0.174679698850878 Pp1-13C protein phosphatase 1 at 13C K06269|1|3e-177|621|dme:Dmel_CG9156|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0044424//intracellular part GO:0004722//protein serine/threonine phosphatase activity GO:0048731;GO:0006909//phagocytosis;GO:0007626//locomotory behavior;GO:0007052//mitotic spindle organization;GO:0007632//visual behavior;GO:0008306//associative learning;GO:0000070//mitotic sister chromatid segregation;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process 326267 471.93 124.3 104.63 -0.248529729262617 Down 0.471470083212257 CG33170 CG33170, isoform C - - - - 19835134 677.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 5740474 1204.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 CG34171 CG34171, isoform C K01362|1|1e-16|86.7|dme:Dmel_CG3795| [EC:3.4.21.-];K09463|2|2e-16|85.9|mmu:626834|kallikrein 13 [EC:3.4.21.-];K01350|3|2e-15|83.2|mdo:100030473|myeloblastin [EC:3.4.21.76] - GO:0008233//peptidase activity - 12798407 664.00 0.135 0.14 0.0524674198941355 Up 0.0419363360190199 CG43190 CG43190 - - - - 19835426 278.00 0.65 0.445 -0.546634382062057 Down 0.137564390437195 40335 3910.00 15.055 19.295 0.357984335816577 Up 0.473385285959583 CG42337 CG42337, isoform C - - - - 42348 1800.54 9.77 8.955 -0.125665129982424 Down 0.19462422401268 Naam nicotinamide amidase, isoform B - - GO:0046872//metal ion binding - 36620 688.00 15.64 18.73 0.260110386935693 Up 0.390833443402457 CG12868 CG12868 - - - - 42470 519.68 1202.02 1119.825 -0.102187607188676 Down 0.267170783251882 RpS30 ribosomal protein S30, isoform C K02983|1|3e-62|236|dme:Dmel_CG15697|small subunit ribosomal protein S30e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 12797866 897.00 0.235 0.255 0.117836490293858 Up 0.0484744419495443 CG43106 CG43106 - - - - 36809 2004.36 4.94 4.145 -0.253138940088927 Down 0.232961299696209 csul capsuleen, isoform B K02516|1|0.0|1216|dme:Dmel_CG3730|protein arginine N-methyltransferase 5 [EC:2.1.1.125] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0008168//methyltransferase activity;GO:0008168//methyltransferase activity GO:0007315//pole plasm assembly;GO:0006996//organelle organization;GO:0000087//M phase of mitotic cell cycle;GO:0006403//RNA localization;GO:0007315//pole plasm assembly;GO:0006996//organelle organization;GO:0000087//M phase of mitotic cell cycle;GO:0006403//RNA localization 38692 1638.00 20.64 15.505 -0.412709444810632 Down 0.509542992999604 CG13295 CG13295 - - - - 41162 1507.54 15.655 14.205 -0.140224676949129 Down 0.246499801875578 bocksbeutel bocksbeutel, isoform B - GO:0012505//endomembrane system;GO:0012505//endomembrane system - GO:0009987//cellular process;GO:0009987//cellular process 40579 903.00 15.485 12.2 -0.343990235224414 Down 0.43963809272223 Dip2 dorsal interacting protein 2 - - GO:0005488//binding - 36956 1473.00 13.31 14.34 0.107534452790013 Up 0.197397965922599 Bap55 brahma associated protein 55kD K11652|1|0.0|857|dsi:Dsim_GD25481|actin-like protein 6B - - - 12798392 573.52 0.405 0.425 0.069540933253077 Up 0.045898824461762 CG43201 CG43201, isoform B - - - - 318792 792.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 CG31544 CG31544 K06233|1|5e-08|43.9|mcc:705786|low density lipoprotein-related protein 2 - - - 36909 1482.00 4.915 6.385 0.377495203362143 Up 0.344901598203672 CG6796 CG6796 K01893|1|0.0|908|dme:Dmel_CG6796|asparaginyl-tRNA synthetase [EC:6.1.1.22] - - - 19836007 691.38 2.85 0.85 -1.7454271729144 Down 0.49976885484084 39268 5558.76 30.19 36.12 0.258727135967233 Up 0.438581429137498 CG42671 CG42671, isoform L - - - - 38600 744.00 9.925 10.79 0.120555857457697 Up 0.192147668735966 CG10673 p53-related protein kinase ortholog K08851|1|3e-126|450|dme:Dmel_CG10673|TP53 regulating kinase [EC:2.7.11.1] GO:0044464//cell part GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0008610//lipid biosynthetic process 40605 2939.00 1.385 1.56 0.17166005281306 Up 0.102232201822745 opa odd paired K09227|1|0.0|694|dme:Dmel_CG1133|zinc finger protein ZIC, invertebrate GO:0044464//cell part GO:0005488//binding GO:0007276//gamete generation;GO:0048565//digestive tract development;GO:0007560//imaginal disc morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 32563 4265.19 44.79 48.725 0.121485519289555 Up 0.275062739400343 CG9170 CG9170, isoform C - - GO:0005488//binding;GO:0005488//binding - 31282 840.00 0.1 0.055 -0.862496476250065 Down 0.0767071721040814 CG3592 CG3592 - - - - 37904 576.00 0.495 0.71 0.520390499425073 Up 0.139776779817726 CG16837 CG16837 K10419|1|2e-13|75.1|dre:394163|dynein light chain roadblock-type GO:0005875//microtubule associated complex - GO:0007017//microtubule-based process 19835090 424.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 50022 2347.00 335.76 125.375 -1.421180667499 Down 0.764991414608374 Hsp70Bbb Hsp70Bbb K03283|1|0.0|1147|dme:Dmel_CG5834|heat shock 70kDa protein 1/8 GO:0015630//microtubule cytoskeleton GO:0032559 GO:0034605//cellular response to heat 39328 2532.00 1.245 1.16 -0.102020936940509 Down 0.0668339717342491 CG14131 CG14131, isoform B - - - - 39809 709.00 22.515 25.835 0.198440406083016 Up 0.355864482895258 mRpS34 mitochondrial ribosomal protein S34 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity - 12798470 1740.19 2.265 3.455 0.609174660342024 Up 0.342920353982301 41944 3952.17 10.125 7.89 -0.359824702645891 Down 0.398230088495575 srp serpent, isoform G K09183|1|8e-21|103|tca:661909|GATA-binding protein 4/5/6 - - - 8674111 1044.30 7.405 10.255 0.469755851191004 Up 0.457667415136706 CG42445 CG42445, isoform B - - - - 246488 1457.06 3.215 4.05 0.33310317044404 Up 0.260071324791969 CG30156 CG30156, isoform B K09518|1|1e-35|150|dmo:Dmoj_GI21983|DnaJ homolog subfamily B member 12 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process 35608 1905.20 13.095 13.22 0.0137061171570955 Up 0.0563994188350284 Cyp6u1 Cyp6u1, isoform C K07424|1|7e-79|295|dgr:Dgri_GH21099|cytochrome P450, family 3, subfamily A [EC:1.14.14.1];K00517|4|3e-76|286|dme:Dmel_CG13977| [EC:1.14.-.-] - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 40369 2280.08 25.795 27.23 0.0781055358911221 Up 0.184684982168802 barc barricade, isoform C K13093|1|0.0|1008|dme:Dmel_CG6049|HIV Tat-specific factor 1 - GO:0005488//binding;GO:0005488//binding - 5740467 2387.00 8.535 15.005 0.81398026057055 Up 0.607515519746401 CG34220 CG34220 - GO:0031224//intrinsic to membrane GO:0030247//polysaccharide binding GO:0006022 39561 4902.75 23.14 13.655 -0.760959550342204 Down 0.634130233786818 CG32138 CG32138, isoform D K04512|1|3e-48|194|dre:557451|dishevelled associated activator of morphogenesis GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization 39261 2538.60 0.91 1.975 1.11791420286577 Up 0.360652489763572 CG14142 CG14142, isoform D - - - - 19835043 500.00 0.25 0.37 0.565597175854225 Up 0.105402192576938 43042 1801.00 62.34 60.555 -0.0419120674237018 Down 0.130530973451327 CG11857 CG11857 - GO:0031224//intrinsic to membrane - - 5740179 876.00 0.41 0.16 -1.35755200461808 Down 0.177321357812706 CG34437 CG34437 K09632|1|1e-18|93.6|gga:427531|chymotrypsin-like protease [EC:3.4.21.-];K01321|2|5e-16|84.7|gga:374258|coagulation factor IX (Christmas factor) [EC:3.4.21.22];K01344|3|3e-15|82.0|ssc:396954|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32620 2449.00 0.02 0.105 2.39231742277876 Up 0.107581561220446 Cnx14D calnexin 14D K08054|1|0.0|1111|dme:Dmel_CG9906|calnexin GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process 31663 1159.18 22.195 22.95 0.0482594449760771 Up 0.128945978074231 CG2059 CG2059, isoform B K13703|1|2e-51|203|aag:AaeL_AAEL007243|abhydrolase domain-containing protein 11 - - - 38075 883.00 62.405 46.005 -0.439870957694423 Down 0.59163254523841 Reg-2 rhythmically expressed gene 2 - - GO:0016791//phosphatase activity - 10178891 2650.00 0.145 0.13 -0.15754127698648 Down 0.045238409721305 CG42730 CG42730 - - - - 41304 1017.00 16.005 18.785 0.23105843909619 Up 0.3632941487254 CG6567 CG6567 K11433|1|4e-155|465|dme:Dmel_CG4565|histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43];K06999|3|1e-134|481|dme:Dmel_CG6567| GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity GO:0006325//chromatin organization 32200 2203.00 0.05 0.045 -0.15200309344505 Down 0.045238409721305 CG15730 meckel syndrome, type 1 homologue - - - - 36292 1719.91 20.795 24.1 0.212796461470968 Up 0.362666754721965 Drep-3 DNA fragmentation factor-related protein 3, isoform B K02310|1|5e-07|56.2|nve:NEMVE_v1g129698|DNA fragmentation factor, 45 kD, alpha subunit GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0005488//binding GO:0012501//programmed cell death;GO:0012501//programmed cell death 39106 2769.49 129.465 126.165 -0.0372503863268437 Down 0.134625544842161 path pathetic, isoform E - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0006865//amino acid transport;GO:0040007//growth;GO:0006865//amino acid transport;GO:0040007//growth 40015 901.00 6.395 5.965 -0.100422221186409 Down 0.135583146215824 rpr reaper - GO:0031966//mitochondrial membrane GO:0008289//lipid binding GO:0008629;GO:0006412//translation;GO:0009894;GO:0009792//embryo development ending in birth or egg hatching;GO:0035071//salivary gland cell autophagic cell death;GO:0032446//protein modification by small protein conjugation;GO:0010623//developmental programmed cell death;GO:0006508//proteolysis;GO:0033554//cellular response to stress 40422 908.00 11.03 5.43 -1.02240868778702 Down 0.6132941487254 CG14572 CG14572 - - - - 19835856 515.00 4.035 3.31 -0.285737456470563 Down 0.233885880332849 43659 1822.00 24.425 18.95 -0.366160713797294 Down 0.501551974640074 CG15546 CG15546 - - - - 5740319 1157.00 1.705 0.08 -4.41362792902417 Down 0.542497688548408 CG34462 CG34462 - - GO:0042302//structural constituent of cuticle - 33196 4008.00 5.085 5.43 0.0947044239468614 Up 0.118181217804781 smo smoothened K06226|1|0.0|1897|dme:Dmel_CG11561|smoothened GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0023060;GO:0009880//embryonic pattern specification;GO:0048592//eye morphogenesis;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0019827//stem cell maintenance;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0035161;GO:0003006//developmental process involved in reproduction;GO:0007560//imaginal disc morphogenesis;GO:0007166//cell surface receptor signaling pathway 37429 1027.00 10.98 9.845 -0.157414943103645 Down 0.239103156782459 Sgf29 SAGA-associated factor 29 ortholog, isoform B - - - - 40814 930.98 29.245 29.23 -0.000740159934604764 Down 0.0416061286487914 CG1307 CG1307, isoform E K04794|1|5e-91|334|dme:Dmel_CG1307|peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity GO:0034660//ncRNA metabolic process;GO:0010467//gene expression;GO:0034660//ncRNA metabolic process;GO:0010467//gene expression 14462359 3921.77 21.015 25.86 0.29930281865828 Up 0.455851274600449 38388 1870.00 1.865 2.13 0.1916777999706 Up 0.124058908994849 CG14965 CG14965 - - GO:0005488//binding - 39636 489.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 CG18649 CG18649, isoform B - - - - 12798198 303.00 0.15 0.17 0.180572245641821 Up 0.0511161009113723 CG43376 CG43376 - - - - 44637 3236.00 0.845 0.735 -0.20120709144582 Down 0.0854576674151367 cutlet cutlet K11269|1|0.0|1786|dme:Dmel_CG33122|chromosome transmission fidelity protein 18 - GO:0004175//endopeptidase activity;GO:0032559;GO:0042623//ATPase activity, coupled GO:0019538//protein metabolic process 41490 411.00 1.275 0.735 -0.794681092022493 Down 0.243990225861841 CG17738 CG17738 - - - - 33983 11558.07 18.545 8.82 -1.07217970694549 Down 0.665367851010435 uif uninflatable, isoform G K02599|1|2e-147|525|spu:575027|Notch - GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0004871//signal transducer activity GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process 33418 1948.02 184.205 173.745 -0.0843407611662074 Down 0.220314357416458 Rab5 Rab5, isoform I K07889|1|1e-122|440|dme:Dmel_CG3664|Ras-related protein Rab-5C GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0065008;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051276//chromosome organization;GO:0007297//ovarian follicle cell migration;GO:0000087//M phase of mitotic cell cycle;GO:0007143//female meiosis;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0006897//endocytosis;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0065008;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051276//chromosome organization;GO:0007297//ovarian follicle cell migration;GO:0000087//M phase of mitotic cell cycle;GO:0007143//female meiosis;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0006897//endocytosis;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0065008;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051276//chromosome organization;GO:0007297//ovarian follicle cell migration;GO:0000087//M phase of mitotic cell cycle;GO:0007143//female meiosis;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0006897//endocytosis;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0065008;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051276//chromosome organization;GO:0007297//ovarian follicle cell migration;GO:0000087//M phase of mitotic cell cycle;GO:0007143//female meiosis;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0006897//endocytosis;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0065008;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051276//chromosome organization;GO:0007297//ovarian follicle cell migration;GO:0000087//M phase of mitotic cell cycle;GO:0007143//female meiosis;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0006897//endocytosis;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0065008;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051276//chromosome organization;GO:0007297//ovarian follicle cell migration;GO:0000087//M phase of mitotic cell cycle;GO:0007143//female meiosis;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0006897//endocytosis;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation 31167 864.24 11.98 8.37 -0.517328380238442 Down 0.498778232730155 CG4325 CG4325, isoform B K11985|1|7e-09|60.1|ame:726290|TRAF-interacting protein - - - 42695 2328.00 0.18 0.19 0.0780025120012732 Up 0.0426627922335227 vret vreteno - - GO:0005488//binding - 36582 4256.00 1.175 0.165 -2.83212282720655 Down 0.405593712851671 Mdr50 multi drug resistance 50 K05658|1|0.0|2361|dme:Dmel_CG8523|ATP-binding cassette, subfamily B (MDR/TAP), member 1 GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 38489 4393.00 17.54 20.6 0.231995589625848 Up 0.371351208558975 Ack activated Cdc42 kinase K08252|1|0.0|1908|dme:Dmel_CG14992|receptor protein-tyrosine kinase [EC:2.7.10.1];K08886|2|8e-138|492|mmu:51789|tyrosine kinase, non-receptor, 2 [EC:2.7.10.1] GO:0016020//membrane;GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0006468//protein phosphorylation 36329 2055.92 1751.5 2398.81 0.453727904000278 Up 0.63056399418835 Cam calmodulin, isoform E K02183|1|2e-79|296|tca:660864|calmodulin GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0042995//cell projection;GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0042995//cell projection GO:0032028//myosin head/neck binding;GO:0046872//metal ion binding;GO:0032028//myosin head/neck binding;GO:0046872//metal ion binding GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0016059//deactivation of rhodopsin mediated signaling;GO:0051294//establishment of spindle orientation;GO:0032412//regulation of ion transmembrane transporter activity;GO:0051276//chromosome organization;GO:0040009//regulation of growth rate;GO:0048870//cell motility;GO:0009790//embryo development;GO:0006915//apoptotic process;GO:0006464//cellular protein modification process;GO:0009593//detection of chemical stimulus;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0000278//mitotic cell cycle;GO:0006909//phagocytosis;GO:0016059//deactivation of rhodopsin mediated signaling;GO:0051294//establishment of spindle orientation;GO:0032412//regulation of ion transmembrane transporter activity;GO:0051276//chromosome organization;GO:0040009//regulation of growth rate;GO:0048870//cell motility;GO:0009790//embryo development;GO:0006915//apoptotic process;GO:0006464//cellular protein modification process;GO:0009593//detection of chemical stimulus;GO:0042993//positive regulation of transcription factor import into nucleus 37066 4320.94 13.535 11.375 -0.250828342241543 Down 0.348170651168934 Sema-5c Semaphorin-5c, isoform B K06841|1|0.0|2105|dme:Dmel_CG5661|semaphorin 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0003676//nucleic acid binding;GO:0004871//signal transducer activity;GO:0003676//nucleic acid binding;GO:0004871//signal transducer activity GO:0007635//chemosensory behavior;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching;GO:0007635//chemosensory behavior;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-dependent;GO:0009792//embryo development ending in birth or egg hatching 41601 1318.00 24.17 17.555 -0.461335476884828 Down 0.548903711530841 CG8031 CG8031 K06990|1|4e-173|607|dme:Dmel_CG8031| - - - 19836197 816.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 - CG45073 - - - - 318652 1653.00 0.37 0.65 0.812914447399505 Up 0.172071060626073 CG31268 CG31268, isoform B - - - - 38024 1886.63 6.625 3.98 -0.735152023794275 Down 0.487386078457271 CG13875 CG13875, isoform B - - - - 42556 3042.00 3.27 2.7 -0.276331228447252 Down 0.204002113327169 CG5849 CG5849, isoform B K11140|1|5e-104|379|dgr:Dgri_GH19253|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 42573 1309.20 1.2 2.06 0.7796099315747 Up 0.307588165367851 CG6569 CG6569, isoform D K10352|1|1e-08|61.6|tgu:100230210|myosin heavy chain - - - 43061 1468.16 212.38 120.855 -0.813370751393647 Down 0.709582617884031 CG10550 CG10550, isoform D - - - - 50072 691.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG42812 CG42812 - - - - 33212 3327.00 14.235 16.105 0.178066167640549 Up 0.295700700039625 ebi ebi K04508|1|0.0|1083|dme:Dmel_CG4063|transducin (beta)-like 1 - GO:0032561//guanyl ribonucleotide binding GO:0042675//compound eye cone cell differentiation;GO:0007049//cell cycle;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006508//proteolysis 41554 1248.00 1.195 0.04 -4.90086680798075 Down 0.488244617619865 CG11598 CG11598 K01046|1|5e-62|238|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|3|2e-56|219|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|5|3e-53|209|xla:734759|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - - - 40663 3836.83 31.52 20.65 -0.610125753149568 Down 0.61804913485669 CG31547 CG31547, isoform B K10951|1|0.0|725|tgu:100230871|solute carrier family 12 member 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015377//cation:chloride symporter activity;GO:0005275//amine transmembrane transporter activity;GO:0015377//cation:chloride symporter activity;GO:0005275//amine transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0006865//amino acid transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0006865//amino acid transport;GO:0030001//metal ion transport 50363 435.00 26.145 25.76 -0.0214024767322244 Down 0.0802403909655263 ksh kish - GO:0031224//intrinsic to membrane - - 318878 1232.06 2.765 4.025 0.541709302767272 Up 0.345198784836878 CG31674 CG31674, isoform B K00049|1|0.0|644|dme:Dmel_CG31674|glyoxylate reductase (NADP+) [EC:1.1.1.79];K00015|2|2e-67|256|hsa:9380|glyoxylate reductase [EC:1.1.1.26];K00058|4|2e-34|146|gga:424381|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] - GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding - 33812 3508.75 6.16 7.275 0.240016897100745 Up 0.268788799366002 TrissinR trissin receptor, isoform E K08378|1|2e-23|111|bfo:BRAFLDRAFT_74637|G protein-coupled receptor 103;K04196|4|3e-22|107|cqu:CpipJ_CPIJ005574|cholecystokinin receptor, invertebrate;K04225|5|5e-22|107|dmo:Dmoj_GI21970|tachykinin receptor, invertebrate GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 34389 2218.81 25.29 25.375 0.00484078529666242 Up 0.0451393475102364 CG5381 CG5381, isoform D - - - - 32746 7693.79 101.195 110.605 0.128278596521143 Up 0.310725135385022 beta-Spec beta spectrin, isoform C K06115|1|0.0|4237|dme:Dmel_CG5870|spectrin beta GO:0043005//neuron projection;GO:0030864//cortical actin cytoskeleton;GO:0044459//plasma membrane part;GO:0045202//synapse GO:0035091//phosphatidylinositol binding;GO:0005198//structural molecule activity;GO:0016787//hydrolase activity;GO:0003779//actin binding;GO:0015631//tubulin binding GO:0016044//cellular membrane organization;GO:0007269//neurotransmitter secretion;GO:0016198//axon choice point recognition;GO:0007019//microtubule depolymerization;GO:0008582//regulation of synaptic growth at neuromuscular junction 36631 3460.00 0.27 0.08 -1.75488750216347 Down 0.158499537709682 CG30479 CG30479, isoform B - - - - 39580 1181.00 2.115 3.14 0.570106895771677 Up 0.313961167613261 CG3868 CG3868 - - - - 42649 1972.50 23.515 21.71 -0.115221606242837 Down 0.242339189010699 T-cp1 Tcp1-like, isoform B K09493|1|0.0|1058|dsi:Dsim_GD18453|T-complex protein 1 subunit alpha GO:0015630//microtubule cytoskeleton;GO:0005743//mitochondrial inner membrane;GO:0015630//microtubule cytoskeleton;GO:0005743//mitochondrial inner membrane GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0032559;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis;GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis 14462810 4863.00 6.84 5.185 -0.399652336072672 Down 0.363954563465857 CG43739 CG43739 - - - - 42324 1421.00 3.07 4.58 0.577108942726765 Up 0.378021397437591 CG3517 CG3517 - - - - 10178885 1894.00 1.675 0.96 -0.803054784623979 Down 0.283416985867125 pre-mod(mdg4)-Y pre-mod(mdg4)-Y - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 19835995 541.00 0.23 0.52 1.17687776208408 Up 0.188284242504293 41562 2566.00 4.54 4.8 0.0803421083176039 Up 0.101043455289922 mbo members only - - - - 42020 938.00 59.805 67.23 0.168839043513063 Up 0.361246863029983 CG10340 CG10340 K07555|1|1e-155|548|dme:Dmel_CG10340|ATP synthase mitochondrial F1 complex assembly factor 1 - - - 42073 914.00 1.485 0.1 -3.8923910259134 Down 0.493032624488179 CG5255 CG5255 K11997|1|3e-38|158|ame:409206|tripartite motif-containing protein 2/3;K01362|2|2e-26|119|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|3|1e-25|117|gga:396345|trypsin [EC:3.4.21.4] - - - 19835375 620.00 0.2 0.295 0.560714954474479 Up 0.0934156650376436 19835483 426.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 41703 1995.00 0.68 0.655 -0.0540398397128889 Down 0.0451063267732136 Orc2 origin recognition complex subunit 2 K02604|1|0.0|1010|dme:Dmel_CG3041|origin recognition complex subunit 2 - - - 41203 3431.00 52.84 66.55 0.332808199552426 Up 0.531831990490028 CG8500 CG8500 K07974|1|2e-112|407|dme:Dmel_CG8500|Ras family, other GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction 37309 960.00 0.045 0.145 1.68805599368526 Up 0.1121384229296 CG11192 CG11192 K01312|1|2e-43|176|dme:Dmel_CG30031|trypsin [EC:3.4.21.4] - - - 19836244 296.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 38664 2288.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 CG10486 CG10486, isoform C K08202|1|4e-50|199|dvi:Dvir_GJ24209|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 33561 1072.00 35.88 36.23 0.0140049155340262 Up 0.0648527275128781 CG12795 CG12795 K07059|1|6e-18|91.3|hsa:79752| - GO:0046914//transition metal ion binding - 37018 1184.00 6.745 7.08 0.0699309171347298 Up 0.110718531237617 CG34195 CG34195 K00599|1|9e-82|303|bta:535332| [EC:2.1.1.-] - - - 34005 4224.74 44.225 48.38 0.129548626402104 Up 0.292134460441157 Ndae1 Na[+]-driven anion exchanger 1, isoform J K13861|1|0.0|1015|dre:798983|solute carrier family 4 (sodium bicarbonate transporter), member 10;K13858|2|0.0|1009|xla:431976|solute carrier family 4 (sodium bicarbonate cotransporter), member 7;K13859|3|0.0|1009|mmu:59033|solute carrier family 4 (sodium bicarbonate cotransporter), member 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015081//sodium ion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity GO:0015698//inorganic anion transport;GO:0006818//hydrogen transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0006818//hydrogen transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0006818//hydrogen transport;GO:0030001//metal ion transport 31515 827.00 0.335 0.69 1.0424352663204 Up 0.209417514198917 CG12729 CG12729 K06700|1|1e-20|100|dpo:Dpse_GA21450|proteasome inhibitor subunit 1 (PI31) - - - 50379 415.00 0.41 0.685 0.740480078342443 Up 0.169594505349359 CG15578 CG15578 - - - - 33551 973.00 1.87 2.085 0.157009113557027 Up 0.110553427552503 CG8838 CG8838 - - - - 40398 2132.70 8.495 9.97 0.230979557213975 Up 0.297021529520539 AP-2 transcription factor AP-2, isoform F K09180|1|0.0|770|dse:Dsec_GM22388|transcription factor AP-2, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007480//imaginal disc-derived leg morphogenesis;GO:0010551;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0010551 31612 3436.48 43.625 59.115 0.438369118874613 Up 0.58978338396513 CG3168 CG3168, isoform G K06258|1|0.0|1148|dme:Dmel_CG3168|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 - - - 35662 2786.00 7.55 8.72 0.207851490564485 Up 0.264000792497689 so sine oculis - GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0016477//cell migration;GO:0001743//optic placode formation;GO:0035270//endocrine system development;GO:0010468//regulation of gene expression;GO:0048592//eye morphogenesis;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent;GO:0007560//imaginal disc morphogenesis;GO:0009605//response to external stimulus 33517 2854.01 0.185 0.37 1 Up 0.14377228899749 CG17258 CG17258, isoform D - - - - 34420 592.00 1244.055 1157.23 -0.104374639553984 Down 0.267203803988905 RpS27A ribosomal protein S27A K02977|1|3e-64|244|dvi:Dvir_GJ21841|small subunit ribosomal protein S27Ae GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0015935//small ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0050896//response to stimulus;GO:0051276//chromosome organization;GO:0022613//ribonucleoprotein complex biogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0006351//transcription, DNA-dependent 8674042 1158.00 0.08 0.115 0.523561956057013 Up 0.0619138819178444 CG42598 CG42598 - GO:0044423 - - 37037 4281.69 22.705 29.285 0.367151857685183 Up 0.515618808611808 CG5036 double hit, isoform C K07524|1|1e-26|122|mdo:100009962|regulator of G-protein signalling 3 - - - 35268 557.48 10.01 9.42 -0.0876430092232103 Down 0.149385814291375 CG10466 CG10466, isoform B K13107|1|3e-88|323|dme:Dmel_CG10466|RNA-binding motif protein, X-linked 2 GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding GO:0000377 53546 1412.00 7.64 8.01 0.0682296043729612 Up 0.114614978206314 CG3021 CG3021 K00566|1|0.0|740|dme:Dmel_CG3021|tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase [EC:2.1.1.61] GO:0044424//intracellular part GO:0003824//catalytic activity GO:0008033//tRNA processing 34881 2705.18 8.295 6.795 -0.287768430188472 Down 0.322909787346454 Su(H) suppressor of hairless, isoform C K06053|1|0.0|1004|dme:Dmel_CG3497|recombining binding protein suppressor of hairless GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016564//transcription repressor activity GO:0007166//cell surface receptor signaling pathway;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048534;GO:0009996//negative regulation of cell fate specification;GO:0051301//cell division;GO:0001709//cell fate determination;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0042386//hemocyte differentiation;GO:0007476//imaginal disc-derived wing morphogenesis 32403 1210.00 0.13 0.18 0.46948528330122 Up 0.0740655131422533 CG5347 CG5347 - - GO:0046914//transition metal ion binding - 36617 5078.00 4.42 4.37 -0.0164130898908331 Down 0.0513472460705323 RpI1 RNA polymerase I subunit K02999|1|0.0|2997|dme:Dmel_CG10122|DNA-directed RNA polymerase I subunit A1 [EC:2.7.7.6] GO:0044452 GO:0034062//RNA polymerase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 32074 746.00 0.745 0.685 -0.121136437501635 Down 0.0636309602430326 CG11756 CG11756 - - - - 3771970 721.00 0.175 0.155 -0.175086706558091 Down 0.0511161009113723 CG33641 CG33641 - - - - 3772037 164.00 1.03 1 -0.0426443374084937 Down 0.0480451723682473 19835485 1455.00 1.09 1.535 0.493910520593253 Up 0.20307753269053 42520 4648.00 13.225 14.645 0.147140470877979 Up 0.252443534539691 Nelf-A negative elongation factor A, isoform C - GO:0031224//intrinsic to membrane GO:0031420;GO:0005267//potassium channel activity GO:0030001//metal ion transport 318682 3310.96 11.32 14.705 0.377432826055182 Up 0.45713908334434 CG31323 CG31323, isoform B - - - - 41848 4118.52 20.95 22.125 0.0787272112710083 Up 0.177387399286752 Cp190 centrosomal protein 190kD, isoform B K10498|1|4e-07|58.2|oaa:100089499|zinc finger and BTB domain-containing protein 11;K10499|2|1e-06|56.6|dre:559081|zinc finger and BTB domain-containing protein 12;K10519|3|2e-06|55.8|bta:534608|zinc finger and BTB domain-containing protein 48 - - - 32148 4490.45 17.885 19.815 0.147842848972758 Up 0.275458988244618 CG10353 CG10353, isoform L K13982|1|7e-34|147|dgr:Dgri_GH10918|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13];K05169|2|4e-15|84.7|ptr:743996|single Ig IL-1R-related molecule - - - 34945 4606.98 9.685 12.13 0.324755596517256 Up 0.39816404702153 beat-Ic beaten path Ic, isoform C - GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0007414//axonal defasciculation;GO:0007411//axon guidance 34779 2032.59 25.095 23.535 -0.0925920930702551 Down 0.199808479725267 CG9008 CG9008, isoform E K01792|1|1e-144|513|dya:Dyak_GE11470|glucose-6-phosphate 1-epimerase [EC:5.1.3.15] - GO:0005488//binding;GO:0003824//catalytic activity;GO:0005488//binding;GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 40005 1739.00 4.25 3.46 -0.29669080338834 Down 0.245641262712984 Cyp312a1 Cyp312a1, isoform B K00517|1|0.0|1003|dme:Dmel_CG5137| [EC:1.14.-.-];K07427|5|1e-71|270|xla:444482|cytochrome P450, family 4, subfamily V GO:0044444//cytoplasmic part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding - 40348 2898.59 343.085 308.59 -0.152874739811707 Down 0.354246466781139 AcCoAS acetyl coenzyme A synthase, isoform D K01895|1|0.0|1338|dse:Dsec_GM22154|acetyl-CoA synthetase [EC:6.2.1.1] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016405//CoA-ligase activity;GO:0032559;GO:0016405//CoA-ligase activity;GO:0032559;GO:0016405//CoA-ligase activity;GO:0032559 - 246548 1039.00 2.52 2.335 -0.110001183790255 Down 0.0951327433628319 CG30338 CG30338 - - - - 42536 1664.00 0.03 0.065 1.11547721741994 Up 0.0725795799762251 tin tinman K09352|1|0.0|650|dme:Dmel_CG7895|homeobox protein Nkx, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009653//anatomical structure morphogenesis;GO:0009888//tissue development;GO:0008354//germ cell migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0048534;GO:0007517//muscle organ development;GO:0045137//development of primary sexual characteristics;GO:0001708//cell fate specification;GO:0009790//embryo development;GO:0042684//cardioblast cell fate commitment;GO:0007431//salivary gland development 33205 898.00 0.135 0.645 2.25633975325979 Up 0.281666886804913 CG11912 CG11912 K01310|1|1e-23|110|cfa:610373|chymotrypsin [EC:3.4.21.1];K01312|2|1e-22|106|dpo:Dpse_GA15051|trypsin [EC:3.4.21.4];K09632|3|1e-22|106|dre:447843|chymotrypsin-like protease [EC:3.4.21.-];K09641|4|2e-22|106|ptr:471225|transmembrane protease, serine 11D [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34228 708.32 0.565 0.405 -0.480328959530563 Down 0.118643508123101 CG13102 CG13102, isoform B - - - - 2768724 444.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 CG33475 CG33475 - - - - 37084 1601.00 23.02 16.12 -0.514036089604263 Down 0.564984810460969 CG5721 CG5721 - - - - 19835798 2914.00 16.915 7.08 -1.25648191171099 Down 0.677915731079118 326225 956.00 0.29 0.505 0.800230487624223 Up 0.150112270505878 CG32633 CG32633, isoform B - - - - 34837 1433.00 10.62 12.155 0.194766127224575 Up 0.283053757759873 mTTF mitochondrial transcription termination factor - GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0006353//DNA-dependent transcription, termination 42982 2511.00 1.175 0.67 -0.810427756107227 Down 0.235801083080174 CG11120 mitotic spindle and nuclear protein K13114|1|1e-07|58.9|dre:407733|pinin - - - 45556 1572.20 71.53 68.74 -0.0573985898153183 Down 0.171905956940959 Cyp6a17 cytochrome P450-6a17, isoform B K00517|1|0.0|975|dme:Dmel_CG10241| [EC:1.14.-.-] GO:0042598 GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 31070 1690.23 3.525 3.425 -0.0415192694382669 Down 0.0640272090873068 CG11398 CG11398, isoform D K09228|1|9e-26|118|mmu:78921|KRAB domain-containing zinc finger protein - - - 38910 1429.00 0.035 0.065 0.893084796083488 Up 0.0629375247655528 mthl7 methuselah-like 7, isoform B K04599|1|3e-90|332|dpo:Dpse_GA19967|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0010259//multicellular organismal aging;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0006887//exocytosis;GO:0010259//multicellular organismal aging;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress 41354 646.19 5.015 5.24 0.0633171109252695 Up 0.0892220314357416 CG17721 CG17721, isoform C - - GO:0046914//transition metal ion binding - 40679 2212.47 363.885 381.1 0.0666870262522717 Up 0.203176594901598 Vha26 vacuolar H[+]-ATPase 26kD subunit, isoform C K02150|1|2e-99|363|dme:Dmel_CG1088|V-type H+-transporting ATPase subunit E [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport;GO:0015986//ATP synthesis coupled proton transport 34915 825.00 0.1 0.585 2.54843662469604 Up 0.278463875313697 CG15254 CG15254, isoform B K08076|1|4e-37|154|cel:C05D11.6|astacin [EC:3.4.24.21];K01395|2|2e-36|152|cin:100181769|meprin A, alpha [EC:3.4.24.18];K08606|3|6e-36|150|dre:100151009|meprin A, beta [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 46006 9164.46 18.915 22.095 0.22418915470763 Up 0.367718927486462 east enhanced adult sensory threshold, isoform G - - - - 34521 3073.00 0.215 0.44 1.0331668639352 Up 0.162726192048607 piwi piwi, isoform B K02156|1|0.0|1629|dme:Dmel_CG6122|aubergine GO:0031981//nuclear lumen;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin GO:0003723//RNA binding GO:0000337;GO:0035194//posttranscriptional gene silencing by RNA;GO:0042078//germ-line stem cell division;GO:0045165//cell fate commitment;GO:0019827//stem cell maintenance 39308 2926.00 0.97 0.67 -0.533823651729355 Down 0.1658961828028 CG6071 CG6071 K11140|1|6e-86|319|dan:Dana_GF22895|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 40595 3093.00 0.315 0.61 0.95345741406297 Up 0.185213313961168 CG17387 CG17387 K10352|1|2e-19|98.2|tgu:100230210|myosin heavy chain - - - 40917 775.00 1.27 0.795 -0.67580173148781 Down 0.218564258354246 CG10919 CG10919 - - - - 40233 2070.00 262.895 250.855 -0.0676330096543252 Down 0.201492537313433 Snap alpha soluble NSF attachment protein - GO:0043231//intracellular membrane-bounded organelle;GO:0033267//axon part;GO:0044425//membrane part - GO:0016079//synaptic vesicle exocytosis;GO:0006909//phagocytosis;GO:0048592//eye morphogenesis;GO:0051301//cell division;GO:0060560//developmental growth involved in morphogenesis;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 14462385 1858.00 0.425 0.39 -0.123988717275453 Down 0.0565645225201427 35524 3259.31 41.15 43.04 0.0647856472476363 Up 0.165863162065777 Src42A Src oncogene at 42A, isoform B K08253|1|0.0|1060|dme:Dmel_CG7873|non-specific protein-tyrosine kinase [EC:2.7.10.2];K08892|2|6e-177|621|cel:F49B2.5|fyn-related kinase [EC:2.7.10.2] GO:0044464//cell part GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0006909//phagocytosis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007391//dorsal closure;GO:0006468//protein phosphorylation;GO:0007015//actin filament organization;GO:0001654//eye development;GO:0009060//aerobic respiration;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0000165//MAPK cascade 37667 989.00 0.475 0.92 0.953706347726065 Up 0.229593184519878 CG13538 CG13538 - - - - 38901 920.00 6.33 6.645 0.070063699847833 Up 0.106557918372738 CG7550 CG7550 K10712|1|9e-108|389|dpo:Dpse_GA20432|cysteamine dioxygenase [EC:1.13.11.19] - GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0008152//metabolic process 39974 1688.00 0.51 0.37 -0.462971976342546 Down 0.110883634922731 CG6034 CG6034 K12259|1|1e-51|204|tgu:100232049|spermine oxidase [EC:1.5.3.16] - - - 41306 1260.00 0.385 0.085 -2.17932369944456 Down 0.210804385153877 CG4570 CG4570 - - GO:0003676//nucleic acid binding;GO:0003824//catalytic activity GO:0006310//DNA recombination 35159 492.00 29.875 36.3 0.28103083512764 Up 0.460011887465328 CG15168 CG15168 - GO:0005769//early endosome;GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0046873//metal ion transmembrane transporter activity GO:0070838//divalent metal ion transport 41899 5086.00 2.755 2.94 0.0937638362652068 Up 0.0906419231277242 pxb pxb, isoform C - - - - 8674113 1023.00 0.115 0.24 1.06140054466414 Up 0.117487782327302 CG42571 CG42571 - - - - 36346 751.00 2.385 0.635 -1.90916076923335 Down 0.480484744419495 CG13155 CG13155 - - - - 38389 2715.07 831.12 553.265 -0.58708613277915 Down 0.675373134328358 Hsp83 heat shock protein 83, isoform B K04079|1|0.0|1202|dme:Dmel_CG1242|molecular chaperone HtpG GO:0005815//microtubule organizing center GO:0005515//protein binding;GO:0032559;GO:0016887//ATPase activity GO:0000278//mitotic cell cycle;GO:0065008;GO:0001752//compound eye photoreceptor fate commitment;GO:0044267//cellular protein metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0042749//regulation of circadian sleep/wake cycle;GO:0022402//cell cycle process;GO:0006950//response to stress;GO:0007316//pole plasm RNA localization 19834878 2301.00 0.02 0.025 0.321928094887362 Up 0.047219653942676 2768678 2127.00 0.1 0.025 -2 Down 0.104411570466253 CG33337 CG33337 K00680|1|0.0|1410|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 3771838 1023.00 0.5 0.025 -4.32192809488736 Down 0.323900409457139 His1:CG33813 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 38644 5415.41 33.04 32.855 -0.00810074463321084 Down 0.0605600316999075 Ubp64E Ubiquitin-specific protease 64E, isoform D K11857|1|0.0|2824|dme:Dmel_CG5486|ubiquitin carboxyl-terminal hydrolase 47 [EC:3.1.2.15] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 40211 1358.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG7290 CG7290, isoform B K01873|1|2e-15|84.0|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 43629 1644.00 0.14 0.055 -1.34792330342031 Down 0.099293356227711 CG9698 CG9698 K00472|1|0.0|1078|dme:Dmel_CG9698|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 38911 2093.00 14.42 12.895 -0.161259391451609 Down 0.264925373134328 CG7979 CG7979 K01710|1|0.0|864|dme:Dmel_CG7979|dTDP-glucose 4,6-dehydratase [EC:4.2.1.46];K08678|2|0.0|755|dpo:Dpse_GA20738|UDP-glucuronate decarboxylase [EC:4.1.1.35] - GO:0048037//cofactor binding GO:0008152//metabolic process 34278 2051.00 0.215 0.29 0.431716240425474 Up 0.0829150706643772 CG3841 CG3841, isoform B K03927|1|0.0|1088|dse:Dsec_GM17558|carboxylesterase type B [EC:3.1.1.1] - GO:0016802;GO:0016802 GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process 36472 592.00 60.22 127.845 1.08608112490718 Up 0.733984942543918 CG10799 CG10799 - - - - 5740677 1110.00 0.14 0.035 -2 Down 0.120855897503632 47091 3085.49 222.49 252.31 0.181456892515405 Up 0.397437590807027 comt comatose, isoform B K06027|1|0.0|1455|dme:Dmel_CG1618|vesicle-fusing ATPase [EC:3.6.4.6] GO:0044424//intracellular part GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0048638//regulation of developmental growth;GO:0006996//organelle organization;GO:0016079//synaptic vesicle exocytosis;GO:0006909//phagocytosis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048193//Golgi vesicle transport 37318 739.36 18.57 4.68 -1.98839338035202 Down 0.730286619997358 CG30148 CG30148, isoform B - - - - 8673967 763.00 0.315 0.52 0.723159794641176 Up 0.140007924976885 CG42536 CG42536 - - - - 4379867 2619.00 17.7 20.87 0.237681240189475 Up 0.380233786818122 CG34155 CG34155 - - - - 33085 2175.89 15.56 9.12 -0.77073633082145 Down 0.603156782459385 CG32512 CG32512, isoform D K07884|1|6e-08|59.7|mdo:100011001|Ras-related protein Rab-3D - - - 43558 2405.93 28.205 33.735 0.25829522489411 Up 0.434850085853916 Tace tace, isoform B K06059|1|0.0|1514|dan:Dana_GF18815|disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 38100 1210.00 20.74 25.21 0.281580224045314 Up 0.435345396909259 CG13890 CG13890 K13239|1|2e-146|518|dme:Dmel_CG13890|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8] GO:0044444//cytoplasmic part - - 36060 3473.48 119.215 133.42 0.162409174845173 Up 0.361048738607846 Pfk phosphofructokinase, isoform E K00850|1|0.0|1437|dwi:Dwil_GK21487|6-phosphofructokinase [EC:2.7.1.11] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005694//chromosome GO:0003676//nucleic acid binding;GO:0008443//phosphofructokinase activity;GO:0032559;GO:0003676//nucleic acid binding;GO:0008443//phosphofructokinase activity;GO:0032559;GO:0003676//nucleic acid binding;GO:0008443//phosphofructokinase activity;GO:0032559 GO:0006007//glucose catabolic process;GO:0016568//chromatin modification;GO:0006007//glucose catabolic process;GO:0016568//chromatin modification;GO:0006007//glucose catabolic process;GO:0016568//chromatin modification 10178872 827.00 0.16 0.225 0.491853096329675 Up 0.0788535200105666 41202 338.30 501.875 1132.35 1.17391996443726 Up 0.752212389380531 MtnA metallothionein A, isoform B - - GO:0043169//cation binding - 19835583 751.00 0.105 0.12 0.192645077942396 Up 0.0514463082816008 45894 3543.00 1.08 0.96 -0.169925001442312 Down 0.0870426627922335 lds lodestar K11727|1|5e-35|150|oaa:100078663|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:3.6.1.-];K11654|4|4e-34|147|nve:NEMVE_v1g226879|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0003715;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0006353//DNA-dependent transcription, termination 42836 4950.72 73.995 102.14 0.465048270996767 Up 0.61851142517501 CG31140 CG31140, isoform H K00901|1|0.0|1348|dse:Dsec_GM26543|diacylglycerol kinase [EC:2.7.1.107] - GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0006796//phosphate-containing compound metabolic process 40457 2470.00 7.05 7.33 0.0561899408476557 Up 0.0989961695945053 Ddx1 Dead-box-1 K13177|1|0.0|1428|dme:Dmel_CG9054|ATP-dependent RNA helicase DDX1 [EC:3.6.4.13] - GO:0042623//ATPase activity, coupled;GO:0032559 GO:0006413//translational initiation;GO:0022613//ribonucleoprotein complex biogenesis;GO:0000398//mRNA splicing, via spliceosome;GO:0009792//embryo development ending in birth or egg hatching 19835082 2626.83 1.97 2.235 0.182079201726942 Up 0.125313697001717 35194 1995.39 30.425 30.84 0.0195455023139436 Up 0.0811319508651433 Aats-asn Asparaginyl-tRNA synthetase, isoform B K01893|1|0.0|1105|dme:Dmel_CG10687|asparaginyl-tRNA synthetase [EC:6.1.1.22] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 38232 1611.00 29.7 28.98 -0.0354053361311989 Down 0.116398098005547 Cdc37 Cdc37 K09554|1|0.0|656|dme:Dmel_CG12019|cell division cycle protein 37 GO:0044424//intracellular part GO:0005515//protein binding;GO:0030295//protein kinase activator activity GO:0007167//enzyme linked receptor protein signaling pathway;GO:0023014//signal transduction by phosphorylation 14462816 354.42 0.685 1.4 1.03125093398444 Up 0.296757363624356 34422 3790.80 8.005 7.715 -0.0532352459455219 Down 0.0960903447364945 Klp31E Kinesin-like protein at 31E, isoform E K10395|1|0.0|1947|dme:Dmel_CG5300|kinesin family member 4/7/21/27 GO:0005875//microtubule associated complex;GO:0005875//microtubule associated complex;GO:0005875//microtubule associated complex;GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process;GO:0007017//microtubule-based process;GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 33988 1928.54 13.83 14.68 0.0860508116927185 Up 0.170651168934091 Rab30 Rab30, isoform D K07917|1|1e-97|357|dme:Dmel_CG9100|Ras-related protein Rab-30 - GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity GO:0035556//intracellular signal transduction;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0006810//transport 44632 1772.00 12.185 9.815 -0.312046078257169 Down 0.389512613921543 Cyp4e1 cytochrome P450-4e1 K00517|1|0.0|1032|dme:Dmel_CG2062| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 34913 988.00 1.45 0.745 -0.960740569552773 Down 0.289426760005283 CG15255 CG15255, isoform B K08076|1|2e-37|156|cel:C05D11.6|astacin [EC:3.4.24.21];K01395|5|9e-35|147|cin:100181769|meprin A, alpha [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39611 2301.79 66.42 42.675 -0.638226569587608 Down 0.657740060758156 bmm brummer, isoform B K13534|1|1e-62|241|mmu:116939|patatin-like phospholipase domain-containing protein 3 [EC:3.1.1.3 2.3.1.-] - GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity GO:0048878//chemical homeostasis;GO:0010259//multicellular organismal aging;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage;GO:0048878//chemical homeostasis;GO:0010259//multicellular organismal aging;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage 3355175 7947.00 0.02 0.045 1.16992500144231 Up 0.0577202483159424 kl-5 male fertility factor kl5 K10408|1|2e-159|564|hsa:146754|dynein heavy chain, axonemal GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 32707 630.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 CG12995 CG12995 - - - - 36600 755.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 Obp50e Odorant-binding protein 50e - - GO:0005488//binding GO:0051234//establishment of localization 32966 1602.16 42.97 49.475 0.203369930160936 Up 0.391196671509708 Rcd-1 required for cell differentiation 1 ortholog, isoform C K12606|1|2e-164|578|dme:Dmel_CG14213|CCR4-NOT transcription complex subunit 9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 38772 938.77 55.505 38.285 -0.535838480825217 Down 0.6255778628979 CG14823 CG14823, isoform D - - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds - 326262 3809.31 8.705 10.13 0.218717971150037 Up 0.289360718531238 CG33123 CG33123, isoform B K01869|1|0.0|2320|dme:Dmel_CG33123|leucyl-tRNA synthetase [EC:6.1.1.4] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 34641 1634.00 0.65 0.835 0.361336479445598 Up 0.124124950468894 Gr33a gustatory receptor 33a K08471|1|0.0|910|dme:Dmel_CG17213|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 3772053 220.00 1.39 0.75 -0.890122382227626 Down 0.273081495178972 32479 696.00 7.475 8.9 0.251731756768293 Up 0.300686831330075 CG6308 CG6308 K07441|1|3e-100|363|dme:Dmel_CG6308|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141] - - - 37016 1603.00 3.115 3.2 0.0388397418633604 Up 0.0603288865407476 CG4975 CG4975, isoform E - - - - 39269 2443.00 4.645 6.17 0.409591892766765 Up 0.35460969488839 Ir68a ionotropic receptor 68a, isoform B K05206|1|2e-07|57.8|dre:793756|glutamate receptor, ionotropic, delta 1 GO:0044464//cell part GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity - 19836242 452.00 0.095 0.11 0.211504105193712 Up 0.0516774534407608 34090 1482.74 17.37 15.345 -0.178829108243908 Down 0.302205785233126 Wwox WW domain containing oxidoreductase, isoform B K00100|1|4e-100|365|dre:393887| [EC:1.1.1.-];K11153|3|2e-41|170|mmu:77974|retinol dehydrogenase 12 [EC:1.1.1.-];K11152|4|4e-40|166|bta:505995|retinol dehydrogenase 11 [EC:1.1.1.-] GO:0044424//intracellular part GO:0003824//catalytic activity;GO:0005488//binding GO:0008152//metabolic process;GO:0010212//response to ionizing radiation 317817 1684.00 1.885 1.475 -0.35384956901946 Down 0.182604675736362 CG32006 CG32006 K09396|1|6e-10|65.9|cin:778609|forkhead box protein C;K09402|2|1e-09|65.1|bfo:BRAFLDRAFT_118651|forkhead box protein J1;K09406|3|1e-09|64.7|gga:430534|forkhead box protein M;K09397|4|2e-09|64.3|mdo:100013010|forkhead box protein D;K09405|5|2e-09|63.9|phu:Phum_PHUM246990|forkhead box protein L - - - 38194 2529.82 9.245 12.87 0.477266828816506 Up 0.490952318055739 GC gamma-glutamyl carboxylase, isoform B K10106|1|0.0|1389|dme:Dmel_CG13927|vitamin K-dependent gamma-carboxylase [EC:6.4.-.-] - GO:0016831//carboxy-lyase activity;GO:0016831//carboxy-lyase activity GO:0018200;GO:0018200 41389 2601.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG5342 CG5342 K05285|1|6e-84|312|dvi:Dvir_GJ20398|phosphatidylinositol glycan, class N [EC:2.7.-.-] GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559 GO:0006810//transport;GO:0006497//protein lipidation 39970 5883.50 10.425 10.775 0.0476404856444342 Up 0.103123761722362 Crtc CREB-regulated transcription coactivator, isoform C - GO:0044424//intracellular part - - 39949 2082.48 9.805 6.53 -0.586434638645718 Down 0.497787610619469 CG7589 CG7589, isoform B K05196|1|1e-45|184|dre:445193|glycine receptor beta;K05195|2|3e-45|183|mmu:110304|glycine receptor alpha-3 GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0005230//extracellular ligand-gated ion channel activity GO:0006909//phagocytosis 33752 647.18 1088.17 908.025 -0.261100036217435 Down 0.498646149782063 TpnC25D troponin C at 25D, isoform C K02183|1|6e-20|97.1|hmg:100200547|calmodulin - GO:0046872//metal ion binding - 43325 1492.00 42.275 74.805 0.823329949088925 Up 0.694227975168406 CG5590 CG5590 K13237|1|9e-15|81.6|cin:100185689|peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34];K11165|3|8e-14|78.6|spu:586029|dehydrogenase/reductase SDR family member 7 [EC:1.1.-.-];K11147|4|2e-13|77.0|aag:AaeL_AAEL006224|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-];K12405|5|2e-13|77.0|dme:Dmel_CG3415|3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase [EC:1.1.1.35 4.2.1.107] GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0003824//catalytic activity;GO:0005496//steroid binding GO:0008152//metabolic process 38200 517.00 6.575 7.55 0.199485750032777 Up 0.240919297318716 CG13919 CG13919 - - - - 44391 2882.00 7.8 8.53 0.12907161756868 Up 0.18686435081231 Nnp-1 Nnp-1 - GO:0043231//intracellular membrane-bounded organelle;GO:0030684//preribosome - GO:0034660//ncRNA metabolic process;GO:0007052//mitotic spindle organization;GO:0042254//ribosome biogenesis 43952 1037.00 5.94 5.8 -0.034410030785831 Down 0.0680227182670717 MED20 mediator complex subunit 20, isoform B K13528|1|8e-134|476|dme:Dmel_CG18780|mediator of RNA polymerase II transcription subunit 20 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0034062//RNA polymerase activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 33291 2547.97 225.27 222.6 -0.0172016049013222 Down 0.0919297318716154 CG4577 CG4577, isoform B - - - - 39633 660.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG18581 CG18581 - - - - 42659 2005.00 65.845 47.75 -0.463573159131757 Down 0.602694492141065 CG33110 CG33110 K10250|1|1e-65|251|cin:100184237|elongation of very long chain fatty acids protein 7;K10247|2|1e-62|241|dre:406725|elongation of very long chain fatty acids protein 1 GO:0031224//intrinsic to membrane - - 32643 681.00 0.76 0.795 0.0649554418407698 Up 0.0489697530048871 CG13010 CG13010 - - - - 19835358 1833.00 32.21 23.08 -0.480865436737332 Down 0.577466649055607 41355 1479.88 14.235 15.46 0.119097826182582 Up 0.218498216880201 CG31388 CG31388, isoform B K09228|1|3e-30|133|ptr:743475|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 34774 1158.22 40.075 35.695 -0.166980518405475 Down 0.342458063663981 ics icarus, isoform C K12796|1|1e-17|90.5|oaa:100091905|erbb2-interacting protein - GO:0005488//binding GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0008587//imaginal disc-derived wing margin morphogenesis 42333 1120.00 0.45 0.12 -1.90689059560852 Down 0.217837802139744 Cpr92A cuticular protein 92A - - GO:0042302//structural constituent of cuticle - 34859 964.00 0.375 0.435 0.214124805352848 Up 0.0691124025888258 CG4650 CG4650, isoform C K01344|1|9e-20|97.4|cfa:476104|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34293 777.00 11.97 11.05 -0.115376782664708 Down 0.196935675604279 Taf11 TBP-associated factor 11 K03135|1|8e-78|290|dme:Dmel_CG4079|transcription initiation factor TFIID subunit D9 GO:0005667//transcription factor complex GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 32648 1263.00 0.8 0.475 -0.752072486556415 Down 0.186203936071853 spheroide spheroide K01362|1|4e-35|149|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|1e-26|120|dme:Dmel_CG18211|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway 43862 2063.25 62.35 73.195 0.23135554034539 Up 0.438746532822613 bl bancal, isoform F K12886|1|5e-146|518|dme:Dmel_CG13425|heterogeneous nuclear ribonucleoprotein K GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0043229//intracellular organelle;GO:0044427//chromosomal part;GO:0016607//nuclear speck GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding GO:0048856//anatomical structure development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007275//multicellular organismal development;GO:0048856//anatomical structure development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007275//multicellular organismal development;GO:0048856//anatomical structure development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007275//multicellular organismal development;GO:0048856//anatomical structure development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007275//multicellular organismal development 33360 882.00 1.325 1.48 0.159604816178388 Up 0.096420552106723 c-cup calcutta cup - - GO:0005506//iron ion binding - 35330 2799.45 29.175 33.58 0.20286957434232 Up 0.373002245410118 Cen centrocortin, isoform B K10352|1|2e-08|62.0|ecb:100063003|myosin heavy chain;K12478|5|2e-07|58.5|mcc:710381|early endosome antigen 1 - - - 38928 2219.68 41.315 34.41 -0.263837775688598 Down 0.447034737815348 cert ceramide transfer protein, isoform C K08283|1|0.0|1149|dme:Dmel_CG7207|Goodpasture-antigen-binding protein kinase [EC:2.7.11.9] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0023060;GO:0033554//cellular response to stress;GO:0043009//chordate embryonic development;GO:0048878//chemical homeostasis;GO:0003012//muscle system process;GO:0032989;GO:0009887//organ morphogenesis;GO:0007005//mitochondrion organization;GO:0046519 326244 1962.00 1.695 0.54 -1.65025396097288 Down 0.397305507858935 CG32985 CG32985 - - - - 37587 981.00 25.2 29.845 0.244065520062524 Up 0.40790516444327 bonsai bonsai - GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 19835392 343.00 0.13 0.145 0.15754127698648 Up 0.0504556861709153 - CG44475 - - - - 36295 10378.00 15.545 18.915 0.283080159708312 Up 0.411504424778761 jeb jelly belly, isoform B - - - GO:0007431//salivary gland development;GO:0006935//chemotaxis;GO:0001707//mesoderm formation;GO:0001751//compound eye photoreceptor cell differentiation 251984 1486.00 74.285 54.33 -0.451321876939857 Down 0.602001056663585 Jheh1 juvenile hormone epoxide hydrolase 1 K10719|1|0.0|930|dme:Dmel_CG15101|juvenile hormone epoxide hydrolase GO:0044464//cell part GO:0004301//epoxide hydrolase activity GO:0006716;GO:0042221//response to chemical stimulus 34504 1183.00 0.305 0.755 1.30766740176219 Up 0.243131686699247 ial IplI-aurora-like kinase K08850|1|0.0|687|dsi:Dsim_GD22216|aurora kinase, other [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0000775//chromosome, centromeric region;GO:0044430//cytoskeletal part GO:0004672//protein kinase activity;GO:0032559 GO:0006468//protein phosphorylation;GO:0000070//mitotic sister chromatid segregation;GO:0051313;GO:0051301//cell division 35526 1626.00 45.78 30.485 -0.586617916899218 Down 0.632082948091401 Act42A actin 42A K05692|1|0.0|761|dwi:Dwil_GK21751|actin beta/gamma 1 GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part GO:0032559 GO:0006996//organelle organization;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0007420//brain development;GO:0051301//cell division;GO:0045185//maintenance of protein location;GO:0003006//developmental process involved in reproduction 36616 3181.37 0.33 0.725 1.13551497065648 Up 0.221172896579052 CG12869 CG12869, isoform C K03927|1|7e-36|152|hsa:8824|carboxylesterase type B [EC:3.1.1.1];K07378|3|2e-33|144|dre:561122|neuroligin - - - 49952 1884.16 1.175 3.1 1.39960745870924 Up 0.478173292827896 CG17450 CG17450, isoform C K04688|1|2e-19|97.4|aag:AaeL_AAEL000743|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization 38107 913.00 0.47 0.155 -1.60039254129076 Down 0.206973979659226 CG13905 CG13905 - - - - 318552 1772.00 1.515 1.845 0.284303022587445 Up 0.153942676000528 gskt gasket K03083|1|5e-152|538|dpo:Dpse_GA22660|glycogen synthase kinase 3 beta [EC:2.7.11.26] - GO:0004672//protein kinase activity;GO:0032559 GO:0007276//gamete generation;GO:0006464//cellular protein modification process;GO:0008406//gonad development 43439 4239.00 3.24 3.68 0.183711953172388 Up 0.160249636771893 yemalpha yemanuclein, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0007292//female gamete generation 36032 5041.91 25.96 27.33 0.0741950765240681 Up 0.171047417778365 Mef2 myocyte enhancer factor 2, isoform H K09263|1|0.0|776|dan:Dana_GF11300|MADS-box transcription enhancer factor 2, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007494//midgut development;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction;GO:0055002//striated muscle cell development;GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007494//midgut development;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction;GO:0055002//striated muscle cell development;GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007494//midgut development;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction;GO:0055002//striated muscle cell development;GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007494//midgut development;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction;GO:0055002//striated muscle cell development;GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007494//midgut development;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-dependent;GO:0003006//developmental process involved in reproduction;GO:0055002//striated muscle cell development 42071 993.00 0.24 0.48 1 Up 0.166325452384097 CG31266 CG31266 K11997|1|2e-29|129|ame:409206|tripartite motif-containing protein 2/3;K01316|2|5e-29|128|dre:100148042|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K09634|3|2e-28|126|bta:537914|transmembrane protease, serine 3 [EC:3.4.21.-];K09751|4|2e-28|126|mmu:319875|transmembrane protease, serine 11B [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33977 1230.00 4.6 3.42 -0.427637536058477 Down 0.320697397965923 Atac1 Ada2a-containing complex component 1 - GO:0000123//histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0016573//histone acetylation 38208 1016.00 731.615 617.045 -0.245708947962181 Down 0.487154933298111 RpL23A ribosomal protein L23A K02893|1|6e-68|257|dme:Dmel_CG7977|large subunit ribosomal protein L23Ae GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0035556//intracellular signal transduction;GO:0010467//gene expression 317913 2989.00 13.39 17.315 0.370866426872918 Up 0.469488838990886 CG32204 CG32204 - GO:0031224//intrinsic to membrane - - 12797919 432.00 0.485 0.545 0.168271482589799 Up 0.0680227182670717 CG43206 CG43206 - - - - 41726 13997.38 5.705 6.74 0.240521704893177 Up 0.259873200369832 DopR dopamine 1-like receptor 1, isoform E K04148|1|0.0|855|dme:Dmel_CG9652|dopamine receptor GO:0016021//integral to membrane GO:0004952//dopamine neurotransmitter receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 19835998 493.00 0.17 0.01 -4.08746284125034 Down 0.187062475234447 - CG45061 - - - - 36419 1698.91 153.535 158.68 0.0475527312308402 Up 0.156650376436402 Nmda1 N-methyl-D-aspartate receptor-associated protein, isoform I K06890|1|7e-137|487|dse:Dsec_GM20327| GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004970//ionotropic glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity - 43005 2703.00 26.84 23.785 -0.174332646237729 Down 0.324858010830802 OstStt3 oligosaccharyl transferase 3 K07151|1|0.0|1500|dme:Dmel_CG7748|dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.1.119] GO:0005789//endoplasmic reticulum membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process 19834718 1826.00 4 4.1 0.0356239097307212 Up 0.0640272090873068 - CG44254 - - GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019842//vitamin binding GO:0008152//metabolic process 38588 682.00 2.25 0.59 -1.9311381418552 Down 0.47127195879012 CG13704 CG13704 - - - - 19835097 1083.00 0.04 0.09 1.16992500144231 Up 0.0797781006472064 31249 1428.00 0.635 1.22 0.94205265079072 Up 0.262184651961432 HLH3B helix loop helix protein 3B K09068|1|2e-21|103|oaa:100079450|T-cell acute lymphocytic leukemia protein - - - 42531 7034.77 33.885 39.435 0.218829871224961 Up 0.402720908730683 CG16791 CG16791, isoform D K12386|1|5e-78|293|nvi:100114326|cystinosin - - - 36513 3501.53 39.1 42.86 0.132463242481833 Up 0.289129573372078 CG6191 CG6191, isoform C - - GO:0019887//protein kinase regulator activity GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0050794//regulation of cellular process 35229 1544.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 CG13084 CG13084 - - - - 40242 1453.00 11.46 11.275 -0.0234796106141616 Down 0.0688152159556201 kin17 kin17 K13102|1|0.0|741|dme:Dmel_CG5649|DNA/RNA-binding protein KIN17 GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding GO:0000377 38017 4185.49 47.86 49.05 0.0354327395681022 Up 0.125742966583014 Pdk1 Phosphoinositide-dependent kinase 1, isoform J K06276|1|0.0|920|dme:Dmel_CG1210|3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0040008//regulation of growth;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process 40678 1859.00 10.235 11.035 0.108575527256203 Up 0.181052701096288 noi noisette K12827|1|0.0|948|dme:Dmel_CG2925|splicing factor 3A subunit 3 GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding GO:0000278//mitotic cell cycle;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0000377;GO:0019953//sexual reproduction 37462 5297.73 6.115 5.945 -0.0406756887817307 Down 0.0758816536785101 mahj mahjong, isoform B K11789|1|0.0|2680|dme:Dmel_CG10080|HIV-1 Vpr-binding protein - - - 37671 2120.00 1.08 2.26 1.06529146025172 Up 0.37742702417118 Klp59C Kinesin-like protein at 59C K10393|1|0.0|1165|dme:Dmel_CG3219|kinesin family member 2/24 GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule GO:0003774//motor activity;GO:0032559 GO:0000819//sister chromatid segregation;GO:0007017//microtubule-based process 38131 3581.21 10.885 14.855 0.448607197647208 Up 0.494881785761458 mwh multiple wing hairs, isoform C - - GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding GO:0030041//actin filament polymerization;GO:0001737//establishment of imaginal disc-derived wing hair orientation;GO:0007166//cell surface receptor signaling pathway 41570 601.00 19.67 9.44 -1.05913819291669 Down 0.668372738079514 CG12279 CG12279 K01010|1|7e-52|202|dme:Dmel_CG12279|thiosulfate sulfurtransferase [EC:2.8.1.1];K02349|2|7e-20|96.7|dme:Dmel_CG6019|DNA polymerase theta subunit [EC:2.7.7.7] - - - 19835745 343.00 0.38 0.01 -5.24792751344359 Down 0.310130762118611 31258 2283.00 9.855 12.215 0.309726087223771 Up 0.389149385814291 CG2681 CG2681 K04506|1|4e-21|103|dvi:Dvir_GJ12343|E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19] - - - 5740749 2099.00 0.08 0.085 0.0874628412503397 Up 0.0429929996037512 31856 1372.00 13.855 14.125 0.0278441567084953 Up 0.0834434024567428 CG12106 CG12106 - - - - 326223 1354.00 0.315 0.475 0.592575684831031 Up 0.121516312244089 Twdlalpha tweedlealpha - - - - 41821 1731.00 27.41 14.035 -0.965673264313251 Down 0.674415532954696 CG3984 CG3984 K06237|1|9e-09|62.0|ptr:452661|collagen, type IV, alpha - - - 40669 2589.00 2.36 2.435 0.0451349127205006 Up 0.0588099326376965 Snm1 Snm1 K10887|1|8e-23|109|cqu:CpipJ_CPIJ014048|DNA cross-link repair 1C protein [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0005261//cation channel activity;GO:0005217//intracellular ligand-gated ion channel activity;GO:0003824//catalytic activity GO:0070838//divalent metal ion transport 19835987 1193.00 0.035 0.12 1.77760757866355 Up 0.101802932241448 39919 7644.09 76.905 93.45 0.281117265514069 Up 0.496863029982829 Rbp6 RNA-binding protein 6, isoform G K13044|1|5e-44|179|gga:396268|heterogeneous nuclear ribonucleoprotein A/B/D GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0005488//binding;GO:0008187//poly-pyrimidine tract binding;GO:0005488//binding;GO:0008187//poly-pyrimidine tract binding - 34269 1733.00 0.655 0.41 -0.675870996919367 Down 0.154338924844803 CG17855 CG17855 K10696|1|1e-06|55.1|nve:NEMVE_v1g247601|E3 ubiquitin-protein ligase BRE1 [EC:6.3.2.19];K04648|2|2e-06|53.9|bmy:Bm1_15810|dynactin 1;K10352|3|4e-06|53.1|cqu:CpipJ_CPIJ015899|myosin heavy chain;K11498|4|4e-06|53.1|rno:362044|centromeric protein E - - - 12797934 665.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 43316 1507.00 16.89 18.07 0.0974271780632139 Up 0.197662131818782 CG5612 CG5612 - - - - 31480 1124.00 27.91 26.595 -0.0696270874462226 Down 0.170453044511954 Sirt4 Sirt4, isoform C K11414|1|3e-156|551|dme:Dmel_CG3187|NAD-dependent deacetylase sirtuin 4 [EC:3.5.1.-] - - - 33401 2323.16 27.67 25.255 -0.131753602178752 Down 0.27073702285035 papi papi, isoform D K13210|1|8e-08|59.3|aag:AaeL_AAEL007042|far upstream element-binding protein;K13162|4|9e-07|55.8|nve:NEMVE_v1g236828|poly(rC)-binding protein 2/3/4 - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 117470 1146.00 0.135 0.23 0.768674453893544 Up 0.101241579712059 Gr93d gustatory receptor 93d K08471|1|0.0|732|dme:Dmel_CG31335|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 46058 852.00 91.815 67.29 -0.448337747720292 Down 0.607878747853652 Prosbeta1 proteasome beta1 subunit K02738|1|4e-114|410|dme:Dmel_CG8392|20S proteasome subunit beta 1 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0006508//proteolysis 31578 767.08 231.19 232.9 0.0106316433642505 Up 0.0698058380663056 CG3446 CG3446, isoform B K00356|1|5e-88|324|dme:Dmel_CG3446|NADH dehydrogenase [EC:1.6.99.3];K00329|2|1e-83|309|dpo:Dpse_GA17457|NADH dehydrogenase [EC:1.6.5.3];K11353|3|1e-15|83.6|xla:447186|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 13 [EC:1.6.5.3 1.6.99.3] - - - 3354921 2553.11 129.905 66.955 -0.956193259849776 Down 0.721371021001189 Gfat1 Glutamine:fructose-6-phosphate aminotransferase 1, isoform N K00820|1|0.0|1386|dme:Dmel_CG12449|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity;GO:0030246//carbohydrate binding;GO:0008483//transaminase activity GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process 43318 1270.02 10.1 13.15 0.380707506540507 Up 0.445383700964206 CG5611 CG5611, isoform C K01692|1|4e-75|281|aga:AgaP_AGAP001715|enoyl-CoA hydratase [EC:4.2.1.17] - - GO:0006909//phagocytosis 42567 5060.35 99.035 111.155 0.16656246159937 Up 0.373101307621186 CASK CASK ortholog, isoform H K06103|1|0.0|1481|aga:AgaP_AGAP001683|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0005856//cytoskeleton;GO:0044459//plasma membrane part;GO:0005624//membrane fraction;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0005856//cytoskeleton;GO:0044459//plasma membrane part;GO:0005624//membrane fraction;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019904//protein domain specific binding;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019904//protein domain specific binding;GO:0032559 GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0015031//protein transport;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0015031//protein transport;GO:0006464//cellular protein modification process 32934 3775.35 12.155 12.625 0.0547334944977906 Up 0.114119667150971 Nat1 NAT1 ortholog, isoform B K00670|1|0.0|1650|dme:Dmel_CG12202|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0008135//translation factor activity, nucleic acid binding;GO:0034212//peptide N-acetyltransferase activity GO:0044260;GO:0048102//autophagic cell death 36421 3463.00 1.26 1.875 0.573466861883327 Up 0.245773345661075 vg vestigial - - - GO:0000278//mitotic cell cycle;GO:0050789//regulation of biological process;GO:0007472//wing disc morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0048592//eye morphogenesis;GO:0007478//leg disc morphogenesis;GO:0035216;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0008283//cell proliferation;GO:0061061//muscle structure development 49638 2291.83 11.27 7.68 -0.553309299451065 Down 0.504688944657245 drm drumstick, isoform C K09215|1|1e-15|85.1|ame:725053|odd-skipped GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0042755//eating behavior;GO:0010468//regulation of gene expression;GO:0002164//larval development;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0040009//regulation of growth rate;GO:0007365//periodic partitioning;GO:0042755//eating behavior;GO:0010468//regulation of gene expression;GO:0002164//larval development;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0040009//regulation of growth rate;GO:0007365//periodic partitioning 43526 814.06 1.34 1.665 0.31328917661349 Up 0.156716417910448 CG15510 CG15510, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 42222 1552.00 1.585 1.255 -0.336795476188635 Down 0.162627129837538 CG10864 CG10864 K05323|1|4e-25|115|cel:C52B9.6|potassium channel subfamily K, invertebrate;K04913|2|5e-18|92.0|rno:170899|potassium channel subfamily K member 2 GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 39643 2854.00 4.435 5.18 0.22401799338549 Up 0.218234050984018 CG6945 CG6945 - - - - 318165 600.00 0.135 0.08 -0.754887502163469 Down 0.0813630960243033 CG32712 CG32712 - - - - 318943 472.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 CG31789 CG31789, isoform C - - - - 19835894 374.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 42184 1034.00 12.095 12.64 0.0635856941971783 Up 0.127658169330339 CG7168 CG7168 - - - - 34595 1704.00 4.19 8.665 1.04824950546082 Up 0.587736098269713 esc extra sexcombs K11462|1|0.0|773|dme:Dmel_CG14941|polycomb protein EED GO:0000785//chromatin;GO:0031519//PcG protein complex GO:0018024//histone-lysine N-methyltransferase activity;GO:0003676//nucleic acid binding GO:0016458//gene silencing;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006338//chromatin remodeling;GO:0034968//histone lysine methylation 19835970 563.00 0.15 0.255 0.765534746362977 Up 0.101241579712059 33208 1806.00 0.835 0.34 -1.29624145122371 Down 0.254920089816405 al aristaless K09452|1|0.0|637|dme:Dmel_CG3935|homeobox protein aristaless-related GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007447//imaginal disc pattern formation;GO:0007423//sensory organ development;GO:0010468//regulation of gene expression;GO:0008593//regulation of Notch signaling pathway;GO:0048800//antennal morphogenesis;GO:0007478//leg disc morphogenesis;GO:0006351//transcription, DNA-dependent 317900 421.00 28.175 1.055 -4.7391007063524 Down 0.859430722493726 edin elevated during infection - - - - 46069 491.23 577.105 572.235 -0.0122260895772661 Down 0.070829480914014 l(2)06225 lethal (2) 06225, isoform D K02140|1|2e-51|201|dan:Dana_GF14048|F-type H+-transporting ATPase subunit g [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 33411 914.00 2.04 2.18 0.0957589828054305 Up 0.0813300752872804 CG17237 CG17237 K12752|1|5e-19|94.7|aga:AgaP_AGAP007806|myosin light chain, invertebrate - GO:0046872//metal ion binding;GO:0016887//ATPase activity - 47895 1176.88 60.7 41.64 -0.543726447843627 Down 0.629177123233391 Nmdmc NAD-dependent methylenetetrahydrofolate dehydrogenase, isoform C K13403|1|5e-172|603|dme:Dmel_CG18466|methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0019238//cyclohydrolase activity;GO:0046872//metal ion binding;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0019238//cyclohydrolase activity GO:0046653//tetrahydrofolate metabolic process;GO:0044238//primary metabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0044238//primary metabolic process 39212 4461.61 15.12 17.005 0.169500866486769 Up 0.289823008849558 simj simjang, isoform E K10310|1|8e-51|202|nvi:100122742|F-box protein 33 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - 37997 559.73 31.81 36.93 0.2153128906661 Up 0.398527275128781 Phk-3 pherokine 3, isoform C K11321|1|8e-09|59.7|tca:661106|bromodomain-containing protein 8;K04352|2|3e-08|57.8|dan:Dana_GF20186|Ras GTPase-activating protein 1 GO:0019898//extrinsic to membrane;GO:0044424//intracellular part GO:0004672//protein kinase activity;GO:0008289//lipid binding GO:0051707//response to other organism;GO:0007264//small GTPase mediated signal transduction;GO:0048598//embryonic morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process 33175 905.00 19.78 14.75 -0.423327471622545 Down 0.511293092061815 CG11454 CG11454 K13188|1|8e-125|446|dme:Dmel_CG11454|RNA-binding protein 7 - GO:0005488//binding - 40614 2000.00 0.535 0.56 0.065887935656457 Up 0.045898824461762 CG14662 CG14662 - - - - 41938 5028.24 328.925 370.295 0.170916404673699 Up 0.385847312112006 Sap47 Synapse-associated protein 47kD, isoform K - - - - 32069 934.00 22.265 22.235 -0.00194520709139553 Down 0.0427618544445912 l(1)10Bb lethal (1) 10Bb K12873|1|2e-85|315|dsi:Dsim_GD15995|bud site selection protein 31 GO:0005681//spliceosomal complex - GO:0000377 35658 676.00 0.71 1.12 0.657607802552922 Up 0.201987848368776 CG11112 CG11112 - - - - 37456 2377.80 19.095 20.21 0.0818744017572213 Up 0.175439175802404 CG10440 CG10440, isoform B - - - - 10178837 3662.96 16.6 25.435 0.615631852628341 Up 0.606789063531898 CG42740 CG42740, isoform C - - - - 34991 4571.19 0.435 0.37 -0.233490130219778 Down 0.0703011491216484 trpgamma transient receptor potential cation channel gamma, isoform D K05328|1|0.0|2210|dme:Dmel_CG5996|transient receptor potential cation channel subfamily C, invertebrate GO:0031224//intrinsic to membrane;GO:0042995//cell projection;GO:0031224//intrinsic to membrane;GO:0042995//cell projection;GO:0031224//intrinsic to membrane;GO:0042995//cell projection GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity GO:0070838//divalent metal ion transport;GO:0009584//detection of visible light;GO:0070838//divalent metal ion transport;GO:0009584//detection of visible light;GO:0070838//divalent metal ion transport;GO:0009584//detection of visible light 42855 968.00 0.125 0.69 2.46466826700344 Up 0.30062078985603 CG10694 CG10694 K10839|1|5e-63|241|dgr:Dgri_GH18491|UV excision repair protein RAD23 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair 37513 1562.00 2.765 1.28 -1.11113567023471 Down 0.418240655131423 CG11475 CG11475 - - - - 34967 887.24 53.73 46.56 -0.206636779798833 Down 0.405131422533351 cni cornichon, isoform C - GO:0016021//integral to membrane;GO:0016021//integral to membrane - GO:0019094//pole plasm mRNA localization;GO:0048193//Golgi vesicle transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0019094//pole plasm mRNA localization;GO:0048193//Golgi vesicle transport;GO:0007173//epidermal growth factor receptor signaling pathway 3354980 642.00 0.32 1.1 1.78135971352466 Up 0.336712455422005 CG40155 CG40155 K12559|1|1e-32|139|tgu:100221738|myosin X - GO:0005488//binding - 37862 2911.00 56.29 61.915 0.137410321880245 Up 0.31406022982433 CG3257 CG3257 - - - - 43087 9729.98 18.105 27.215 0.588013859248916 Up 0.603949280147933 msi musashi, isoform H K13044|1|3e-41|171|gga:396268|heterogeneous nuclear ribonucleoprotein A/B/D GO:0005626//insoluble fraction;GO:0031224//intrinsic to membrane;GO:0005626//insoluble fraction;GO:0031224//intrinsic to membrane GO:0030371//translation repressor activity;GO:0003723//RNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0003723//RNA binding;GO:0005102//receptor binding GO:0006412//translation;GO:0006396//RNA processing;GO:0045165//cell fate commitment;GO:0007281//germ cell development;GO:0006412//translation;GO:0006396//RNA processing;GO:0045165//cell fate commitment;GO:0007281//germ cell development 34702 2041.00 2.315 1.615 -0.519478028566311 Down 0.25775987320037 CG5142 CG5142, isoform D - GO:0042995//cell projection;GO:0005874//microtubule - GO:0010970//microtubule-based transport;GO:0018200 34778 2463.49 28.93 32.79 0.180689578463461 Up 0.346321489895654 TM9SF4 TM9SF4, isoform B - GO:0031224//intrinsic to membrane - GO:0042742//defense response to bacterium;GO:0006909//phagocytosis;GO:0002252 14462550 599.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 41707 1981.00 71.805 86.435 0.267531312343167 Up 0.483885880332849 CG3061 CG3061 K09518|1|3e-180|632|dme:Dmel_CG3061|DnaJ homolog subfamily B member 12 - - - 19835148 382.00 0.56 0.755 0.431049817267475 Up 0.12696473385286 31487 3674.00 8.285 8.77 0.0820751452232811 Up 0.132908466516973 CG3160 CG3160 K05294|1|0.0|1785|dme:Dmel_CG3160|glycosylphosphatidylinositol deacylase [EC:3.-.-.-] - - - 38557 1645.00 13.28 1.73 -2.9404112037102 Down 0.751981244221371 CG13720 CG13720 - - - - 40813 6718.73 11.17 11.765 0.0748721347409828 Up 0.137333245278035 Taf1 TBP-associated factor 1, isoform F K03125|1|0.0|3556|dme:Dmel_CG17603|transcription initiation factor TFIID subunit D1 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006352//DNA-dependent transcription, initiation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006352//DNA-dependent transcription, initiation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006352//DNA-dependent transcription, initiation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006352//DNA-dependent transcription, initiation;GO:0000086//G2/M transition of mitotic cell cycle 33445 2734.49 39.69 42.37 0.0942675663640574 Up 0.219125610883635 Drp1 dynamin related protein 1, isoform B K01528|1|0.0|1409|dme:Dmel_CG3210|dynamin GTPase [EC:3.6.5.5] GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0048311//mitochondrion distribution;GO:0051301//cell division;GO:0007033//vacuole organization;GO:0048488//synaptic vesicle endocytosis;GO:0006914//autophagy 50373 375.75 35.395 46.145 0.382628758984688 Up 0.549068815215956 CG17776 CG17776, isoform B - - - - 34310 2937.12 92.65 83.925 -0.142690344329716 Down 0.324824990093779 CG13124 CG13124, isoform J - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0044260;GO:0044260;GO:0044260;GO:0044260;GO:0044260;GO:0044260;GO:0044260;GO:0044260;GO:0044260 36187 1359.00 0.115 0.295 1.35908109330483 Up 0.148461233654735 Or47a odorant receptor 47a K08471|1|0.0|751|dme:Dmel_CG13225|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 37225 2747.00 0.4 0.205 -0.964376090269279 Down 0.147635715229164 CG10073 CG10073, isoform C - - - - 38633 1796.00 1.2 0.305 -1.97615325804563 Down 0.363756439043719 CG5150 CG5150, isoform B K01077|1|0.0|1048|dme:Dmel_CG5150|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 5740441 577.00 1.435 1.565 0.125111920256931 Up 0.0851274600449082 CG34161 CG34161, isoform C K01512|1|6e-53|206|dya:Dyak_GE13517|acylphosphatase [EC:3.6.1.7] - GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides - 19835854 708.00 0.465 0.925 0.992222649408281 Up 0.233225465592392 32819 1276.00 11.29 11.9 0.0759160874223051 Up 0.145654471007793 CG6179 CG6179 K13125|1|8e-158|556|dme:Dmel_CG6179|nitric oxide synthase-interacting protein GO:0005681//spliceosomal complex GO:0005488//binding GO:0000377;GO:0044092//negative regulation of molecular function 42455 2635.83 38.28 87.07 1.185584893517 Up 0.73586712455422 CG42322 CG42322, isoform N - - GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 33888 1148.00 0.04 0.08 1 Up 0.0725795799762251 CG9500 CG9500 K10104|1|2e-68|258|dwi:Dwil_GK15354|ficolin - GO:0005515//protein binding GO:0023060 37981 12745.86 38.895 48.32 0.313035747750628 Up 0.502707700435874 NaCP60E Na channel protein 60E, isoform P K05388|1|0.0|762|spu:588616|voltage-gated sodium channel alpha, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005272//sodium channel activity;GO:0005272//sodium channel activity GO:0030001//metal ion transport;GO:0030001//metal ion transport 19835487 480.00 5.125 3.935 -0.381188368885322 Down 0.315017831197992 38459 1083.83 111.855 117.67 0.0731168043863764 Up 0.195879012019548 mge maggie, isoform C - GO:0005741//mitochondrial outer membrane;GO:0005741//mitochondrial outer membrane GO:0008320//protein transmembrane transporter activity;GO:0008320//protein transmembrane transporter activity GO:0015031//protein transport;GO:0015031//protein transport 19835044 482.00 0.01 0.305 4.93073733756289 Up 0.275194822348435 32687 6926.38 35.5 34.87 -0.0258326605027021 Down 0.100482102760534 CG9086 CG9086, isoform C K10626|1|0.0|3524|dme:Dmel_CG9086|E3 ubiquitin-protein ligase UBR2 [EC:6.3.2.19] GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0009057//macromolecule catabolic process;GO:0032446//protein modification by small protein conjugation 42575 1184.00 3.205 3.965 0.306996509085237 Up 0.24385814291375 CG31178 CG31178 - - - - 40342 2369.80 36.765 36.685 -0.00314269976611352 Down 0.0449742438251222 CG10508 CG10508, isoform L - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 34709 4350.28 11.645 12.425 0.0935352122387825 Up 0.166259410910052 Sfmbt Scm-related gene containing four mbt domains, isoform D K11465|1|3e-24|115|mcc:694404|sex comb on midleg-like protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding GO:0016458//gene silencing;GO:0007292//female gamete generation;GO:0007444//imaginal disc development;GO:0006325//chromatin organization;GO:0016458//gene silencing;GO:0007292//female gamete generation;GO:0007444//imaginal disc development;GO:0006325//chromatin organization;GO:0016458//gene silencing;GO:0007292//female gamete generation;GO:0007444//imaginal disc development 14462356 745.00 2.355 2.16 -0.124695747449315 Down 0.0972790912693171 33120 590.00 21.68 56.895 1.39193711566152 Up 0.741843877955356 lcs la costa - - - - 37451 2468.33 201.27 202.415 0.00818405564558179 Up 0.0689472989037115 MESK2 misexpression suppressor of KSR 2, isoform K - - - - 45683 4913.72 57.095 58.67 0.0392585825165942 Up 0.129210143970413 milt milton, isoform F - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007005//mitochondrion organization;GO:0003006//developmental process involved in reproduction;GO:0008088//axon cargo transport;GO:0007005//mitochondrion organization;GO:0003006//developmental process involved in reproduction;GO:0008088//axon cargo transport;GO:0007005//mitochondrion organization;GO:0003006//developmental process involved in reproduction;GO:0008088//axon cargo transport 41879 1545.00 2.19 3.17 0.533551970538234 Up 0.304087967243429 h-cup heineken-cup - - - - 42985 3248.00 27.905 24.885 -0.165247259373327 Down 0.323900409457139 Osbp oxysterol binding protein K08283|1|1e-15|85.9|aga:AgaP_AGAP007093|Goodpasture-antigen-binding protein kinase [EC:2.7.11.9] - GO:0032934//sterol binding GO:0006810//transport;GO:0006629//lipid metabolic process 40010 2023.00 0.04 0.01 -2 Down 0.0694426099590543 CG7320 CG7320 K00505|1|5e-13|76.3|dya:Dyak_GE14257|tyrosinase [EC:1.14.18.1] - GO:0022892 GO:0051234//establishment of localization 36043 2015.51 17.71 22.45 0.342151232876595 Up 0.475267467969885 CG1407 CG1407, isoform G - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 36989 2233.00 19.61 20.665 0.0755998281823912 Up 0.172698454629507 ns2 nucleostemin ortholog 2 - - - - 5740175 497.00 1.98 2.31 0.222392421336448 Up 0.144762911108176 CG34160 CG34160 - - - - 44359 4827.77 29.255 35.04 0.260319556781904 Up 0.43709549597147 sda slamdance, isoform D K11140|1|2e-155|550|nvi:100124286|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0009612//response to mechanical stimulus;GO:0019538//protein metabolic process;GO:0009612//response to mechanical stimulus 36465 1024.00 5.22 4.755 -0.134604465709321 Down 0.15199445251618 CG4676 CG4676 - - GO:0046914//transition metal ion binding - 14462419 1380.00 0.06 0.035 -0.777607578663552 Down 0.0552767137762515 45680 805.00 71.245 69.97 -0.0260522772023094 Down 0.108803328490292 Tapdelta Translocon-associated protein delta, isoform B K04571|1|2e-37|155|cqu:CpipJ_CPIJ002042|translocon-associated protein subunit delta GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0048500//signal recognition particle GO:0042277//peptide binding GO:0035437//maintenance of protein localization in endoplasmic reticulum 37621 2174.00 0.835 0.775 -0.107579887199815 Down 0.0625082551842557 CG42284 CG42284, isoform E K10380|1|2e-07|58.2|dse:Dsec_GM23234|ankyrin;K04469|3|2e-06|54.3|ecb:100069984|nuclear factor of kappa light polypeptide gene enhancer in B-cells 2;K10645|4|3e-06|53.9|spu:579155|E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19] - - - 39323 1467.00 0.265 0.32 0.272079545436801 Up 0.0687821952185973 CG32087 CG32087 - GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization 31335 2032.51 33.365 34.105 0.0316477587536193 Up 0.102892616563202 HIP-R Hsc/Hsp70-interacting protein related, isoform D K09560|1|3e-63|243|dre:564225|suppressor of tumorigenicity protein 13 - - - 33476 1194.00 7.01 8.67 0.306617549211212 Up 0.343613789459781 CG15400 Glucose-6-Phosphatase K01084|1|0.0|695|dme:Dmel_CG15400|glucose-6-phosphatase [EC:3.1.3.9];K00276|5|7e-18|91.7|tgu:100190280|primary-amine oxidase [EC:1.4.3.21] GO:0044464//cell part GO:0046872//metal ion binding;GO:0003824//catalytic activity - 36802 579.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG7786 CG7786 K09056|1|3e-16|84.7|ecb:100146301|albumin D box-binding protein GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent 318261 706.00 0.675 0.88 0.382616021586466 Up 0.127592127856294 CG32945 CG32945 - - - - 37684 1232.00 0.25 0.66 1.40053792958373 Up 0.234546295073306 RpL22-like ribosomal protein L22-like K02891|1|2e-34|146|der:Dere_GG12744|large subunit ribosomal protein L22e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization 40314 1959.00 38.14 31.445 -0.278474208061953 Down 0.462488442742042 fng fringe K05948|1|0.0|804|dse:Dsec_GM22178|fringe [EC:2.4.1.222] GO:0031228//intrinsic to Golgi membrane GO:0008375//acetylglucosaminyltransferase activity GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0003006//developmental process involved in reproduction;GO:0045165//cell fate commitment;GO:0035110;GO:0048592//eye morphogenesis;GO:0006486//protein glycosylation;GO:0019318//hexose metabolic process;GO:0007292//female gamete generation;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway 42846 3409.80 12.98 14.025 0.111710387497017 Up 0.198289525822216 spas spastin, isoform D K13254|1|0.0|1205|dme:Dmel_CG5977|spastin [EC:3.6.4.3] GO:0005815//microtubule organizing center;GO:0031224//intrinsic to membrane;GO:0033267//axon part;GO:0005815//microtubule organizing center;GO:0031224//intrinsic to membrane;GO:0033267//axon part GO:0042623//ATPase activity, coupled;GO:0015631//tubulin binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0015631//tubulin binding;GO:0032559 GO:0007019//microtubule depolymerization;GO:0048869//cellular developmental process;GO:0048731;GO:0050804//regulation of synaptic transmission;GO:0000087//M phase of mitotic cell cycle;GO:0007610//behavior;GO:0007019//microtubule depolymerization;GO:0048869//cellular developmental process;GO:0048731;GO:0050804//regulation of synaptic transmission;GO:0000087//M phase of mitotic cell cycle;GO:0007610//behavior 43039 687.68 481.085 491.795 0.0317652497814245 Up 0.116464139479593 RpS27 ribosomal protein S27, isoform B K02978|1|6e-47|187|dpo:Dpse_GA10310|small subunit ribosomal protein S27e GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex GO:0043169//cation binding;GO:0005198//structural molecule activity GO:0010467//gene expression 41143 2839.00 6.18 7 0.179748083927954 Up 0.216483951921807 JHDM2 JmjC domain-containing histone demethylase 2, isoform B K11449|1|0.0|1742|dme:Dmel_CG8165|jumonji domain-containing protein 1 [EC:1.14.11.-] - - - 40000 2259.99 19.36 13.705 -0.498376624448819 Down 0.544776119402985 CG13698 CG13698, isoform C - - - - 38888 1295.00 33.225 23.635 -0.491344334804887 Down 0.583773609826971 CG8209 CG8209 K14011|1|8e-06|52.0|nvi:100118419|UBX domain-containing protein 6 - - - 40272 1483.58 242.37 272.685 0.170024205513183 Up 0.383833047153612 CG6020 CG6020, isoform B K03953|1|0.0|814|dme:Dmel_CG6020|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 9 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0048037//cofactor binding GO:0022904//respiratory electron transport chain 326197 2094.00 51.785 51.735 -0.00139363905822689 Down 0.0441487253995509 Ndfip Nedd4 family interacting protein - - - - 38682 904.00 41.97 49.05 0.224894673220692 Up 0.414080042266543 Jon65Aiv jonah 65Aiv K01310|1|2e-105|382|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|4|3e-60|231|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19835654 540.00 1.12 0.185 -2.59790155642865 Down 0.387300224541012 44226 2134.10 162.36 170.54 0.0709139165847843 Up 0.198982961299696 Xbp1 X box binding protein-1, isoform E K09027|1|2e-130|466|dme:Dmel_CG9415|X box-binding protein 1 - GO:0003677//DNA binding - 40997 1522.00 1.015 1.465 0.529420937237072 Up 0.205422005019152 CG7352 CG7352, isoform C K06084|1|5e-19|95.9|spu:591791|F-box protein 20 - - - 37999 2356.38 294.715 181.23 -0.701498698236517 Down 0.694294016642451 emp epithelial membrane protein, isoform E K13885|1|5e-67|256|gga:416814|scavenger receptor class B, member 1;K12384|3|2e-65|251|bta:533177|lysosome membrane protein 2 GO:0000323//lytic vacuole;GO:0016021//integral to membrane;GO:0000323//lytic vacuole;GO:0016021//integral to membrane;GO:0000323//lytic vacuole;GO:0016021//integral to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0048102//autophagic cell death;GO:0006950//response to stress;GO:0048102//autophagic cell death;GO:0006950//response to stress;GO:0048102//autophagic cell death;GO:0006950//response to stress 43207 1088.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 TwdlN TweedleN - - - - 33333 684.00 1.745 0.92 -0.92352127015264 Down 0.310163782855633 CG18132 CG18132 K13984|1|7e-17|87.0|phu:Phum_PHUM126760|thioredoxin domain-containing protein 5 - - GO:0019725//cellular homeostasis 35669 1726.19 2.27 1.9 -0.256692878959967 Down 0.158862765816933 CG11125 CG11125, isoform C - - - - 38663 1141.00 49.06 23.95 -1.03452157793406 Down 0.709615638621054 QC glutaminyl cyclase K00683|1|1e-73|276|tca:659407|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] - GO:0016755;GO:0016787//hydrolase activity GO:0019538//protein metabolic process 49997 762.23 8.165 5.29 -0.626185163447669 Down 0.484381191388192 CG11052 CG11052, isoform D K01512|1|2e-71|268|dme:Dmel_CG11052|acylphosphatase [EC:3.6.1.7] - GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides - 43618 2589.14 33.25 30.38 -0.130232470773831 Down 0.279619601109497 CDase ceramidase, isoform F K12349|1|0.0|1439|dme:Dmel_CG1471|neutral ceramidase [EC:3.5.1.23] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0006906//vesicle fusion;GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0006672//ceramide metabolic process;GO:0007610//behavior;GO:0006906//vesicle fusion;GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0006672//ceramide metabolic process;GO:0007610//behavior;GO:0006906//vesicle fusion;GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0006672//ceramide metabolic process;GO:0007610//behavior;GO:0006906//vesicle fusion;GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0006672//ceramide metabolic process;GO:0007610//behavior;GO:0006906//vesicle fusion;GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0006672//ceramide metabolic process;GO:0007610//behavior 33200 748.00 15.5 20.8 0.424315312866854 Up 0.515816933033945 CG11562 CG11562 - - - - 33526 5463.72 36.475 42.77 0.229691229071081 Up 0.417613261127988 toc toucan, isoform J K10352|1|1e-10|69.7|mcc:717865|myosin heavy chain;K04514|3|6e-10|67.8|mmu:19877|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005635//nuclear envelope GO:0019900//kinase binding;GO:0004175//endopeptidase activity;GO:0019900//kinase binding;GO:0004175//endopeptidase activity;GO:0019900//kinase binding;GO:0004175//endopeptidase activity;GO:0019900//kinase binding;GO:0004175//endopeptidase activity;GO:0019900//kinase binding;GO:0004175//endopeptidase activity;GO:0019900//kinase binding;GO:0004175//endopeptidase activity GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction;GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction;GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction;GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction;GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction;GO:0000819//sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0019538//protein metabolic process;GO:0003006//developmental process involved in reproduction 35651 1404.00 0.805 0.695 -0.211975805391109 Down 0.0858208955223881 CG12164 CG12164, isoform B - - - - 39262 3410.76 35.945 43.535 0.276384619627225 Up 0.468960507198521 GlcAT-P GlcAT-P, isoform E K10812|1|0.0|636|dme:Dmel_CG6207|beta-1,3-glucuronyltransferase [EC:2.4.1.135 2.4.1.-] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0015020//glucuronosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0015020//glucuronosyltransferase activity GO:0006687//glycosphingolipid metabolic process;GO:0006029//proteoglycan metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006029//proteoglycan metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006029//proteoglycan metabolic process 34631 1336.00 5.215 5.24 0.0068995590176847 Up 0.0453704926693964 CG6712 CG6712 - - GO:0003676//nucleic acid binding;GO:0016876//ligase activity, forming aminoacyl-tRNA and related compounds;GO:0032559 GO:0010467//gene expression 41609 2174.00 4.66 3.165 -0.558124455225939 Down 0.374323074891032 Hsc70-2 heat shock protein cognate 2 K03283|1|0.0|1170|dme:Dmel_CG7756|heat shock 70kDa protein 1/8 - - - 40941 2123.45 135.735 133.1 -0.0282822041551175 Down 0.11306300356624 CD98hc CD98 heavy chain, isoform F K06519|1|0.0|846|dpo:Dpse_GA15464|solute carrier family 3, member 2 - GO:0043167//ion binding GO:0044238//primary metabolic process;GO:0015820//leucine transport 43936 3145.05 121.925 126.42 0.0522307476152326 Up 0.156022982432968 Men-b malic enzyme b, isoform C K00029|1|0.0|1198|dme:Dmel_CG5889|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding GO:0032787//monocarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process 40900 637.00 1.965 3.215 0.710289425069341 Up 0.360388323867389 Ubc84D ubiquitin conjugating enzyme 84D K04552|1|4e-85|313|dme:Dmel_CG12799|ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0006464//cellular protein modification process 40642 1927.00 1.66 1.03 -0.688538904163706 Down 0.255580504556862 hd humpty dumpty K00698|1|5e-71|268|dse:Dsec_GM10642|chitin synthase [EC:2.4.1.16] GO:0043231//intracellular membrane-bounded organelle GO:0016757//transferase activity, transferring glycosyl groups GO:0071897//DNA biosynthetic process;GO:0051320//S phase 14462619 1000.00 0.045 0.09 1 Up 0.0796790384361379 33439 1844.00 14.66 7.405 -0.985313462844964 Down 0.633172632413155 Cyp309a2 Cyp309a2 K00517|1|0.0|1011|dme:Dmel_CG18559| [EC:1.14.-.-] - GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 34386 936.00 28.535 23.72 -0.266628553130447 Down 0.433397173424911 CG5385 lethal (2) SH0834 - - - - 34812 1413.00 561.42 263.895 -1.08911644298533 Down 0.744617619865275 CG16884 CG16884 K03426|1|8e-06|52.0|oaa:100074267|NAD+ diphosphatase [EC:3.6.1.22] - - - 36876 7339.45 175.58 202.565 0.206256401536315 Up 0.434916127327962 unc-104 unc-104 ortholog, isoform H K10392|1|0.0|3161|dya:Dyak_GE14036|kinesin family member 1/13/14 - - - 37437 3041.15 8.115 7.59 -0.0964912091325052 Down 0.148692378813895 CG30394 CG30394, isoform B K13576|1|1e-16|89.4|oaa:100077697|sodium-coupled neutral amino acid transporter 3 - - - 34202 925.00 0.3 0.565 0.913288366806669 Up 0.173028661999736 CG12438 CG12438 - - - - 5740609 932.00 0.13 0.05 -1.37851162325373 Down 0.099524501386871 CG34290 CG34290 K09643|1|2e-26|119|mcc:698586|transmembrane protease, serine 13 [EC:3.4.21.-];K08664|2|3e-26|119|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-];K01317|4|2e-25|116|mdo:100010132|acrosin [EC:3.4.21.10];K08648|5|5e-25|114|ecb:100068293|hyaluronan binding protein 2 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39983 1872.00 0.025 0.025 0 - 0.0382380134724607 Ir75c ionotropic receptor 75c K05202|1|3e-08|60.5|bfo:BRAFLDRAFT_128813|glutamate receptor, ionotropic, kainate 2 GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 14462774 434.00 92.01 48.59 -0.92113123487089 Down 0.712191256108836 CG44141 CG44141 - - - - 42599 1335.00 0.06 0.105 0.807354922057604 Up 0.07657508915599 CG13407 CG13407 - - - - 41367 3243.00 5.11 5.145 0.00984778595634689 Up 0.0453704926693964 Ranbp9 Ranbp9, isoform D - - GO:0022892 GO:0015031//protein transport 42358 4034.00 24.97 25.435 0.0266192729344166 Up 0.095760137366266 Ire1 Inositol-requiring enzyme-1 K08852|1|0.0|2094|dme:Dmel_CG4583|serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] - GO:0004521//endoribonuclease activity;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006396//RNA processing 40798 1167.00 0.04 0.12 1.58496250072116 Up 0.101736890767402 CG15185 CG15185 - - - - 19836089 595.00 0.01 0.08 3 Up 0.110718531237617 - CG44329 - - - - 31617 1789.70 10.4 7.13 -0.544609546584566 Down 0.489895654471008 shf shifted, isoform D K01691|1|0.0|922|dme:Dmel_CG3135|WNT inhibitory factor 1 - - - 14462579 500.00 0.335 0.115 -1.54252723440076 Down 0.167844406287148 31264 719.00 0.17 0.45 1.40439025507934 Up 0.190166424514595 CG2709 CG2709 - - - - 14462511 565.00 0.01 0.165 4.04439411935845 Up 0.184883106590939 33192 2417.00 2.88 3.815 0.405614245392218 Up 0.28417646281865 CG3345 CG3345 - - - - 3355149 1161.00 7.33 3.865 -0.923344784208964 Down 0.543257165499934 CG40298 CG40298 - - - - 3772064 1570.00 12.835 13.63 0.086702266229791 Up 0.1670519085986 DNApol-gamma35 DNA polymerase gamma 35kD K02333|1|0.0|666|dme:Dmel_CG33650|DNA polymerase gamma 2;K12385|2|2e-21|104|cqu:CpipJ_CPIJ004884|Niemann-Pick C1 protein GO:0005759//mitochondrial matrix GO:0034061;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006448//regulation of translational elongation;GO:0006261//DNA-dependent DNA replication;GO:0007005//mitochondrion organization;GO:0006418//tRNA aminoacylation for protein translation 42007 1089.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 Gr89a gustatory receptor 89a K08471|1|0.0|659|dme:Dmel_CG14901|gustatory receptor - - - 246566 2074.00 0.16 0.365 1.18982455888002 Up 0.1536124686303 cola comas sola - - - - 33180 1263.53 27.525 29.475 0.0987492494153939 Up 0.222790912693171 CG3436 CG3436, isoform C K12857|1|0.0|717|dme:Dmel_CG3436|Prp8 binding protein GO:0005681//spliceosomal complex - GO:0000377 39864 3684.06 28.935 30.11 0.0574270639544177 Up 0.154636111478008 Lasp lasp, isoform D K10356|1|1e-07|59.7|isc:IscW_ISCW012705|myosin I;K04364|2|3e-07|58.5|nve:NEMVE_v1g229989|growth factor receptor-binding protein 2 GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding GO:0007317//regulation of pole plasm oskar mRNA localization;GO:0048232//male gamete generation;GO:0007317//regulation of pole plasm oskar mRNA localization;GO:0048232//male gamete generation 32050 1831.00 11.225 10.395 -0.11082568677014 Down 0.183364152687888 CG18292 CG18292, isoform B - - - - 35694 2630.45 16.035 13.11 -0.290556668219892 Down 0.403777572315414 blow blown fuse, isoform D - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part - GO:0014706//striated muscle tissue development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0014706//striated muscle tissue development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0014706//striated muscle tissue development;GO:0000768//syncytium formation by plasma membrane fusion 2768671 2461.57 61.05 19.665 -1.63436110893185 Down 0.757330603619073 Pxd peroxidase, isoform C K12550|1|8e-73|275|bta:280844|lactoperoxidase [EC:1.11.1.7];K00431|2|9e-71|268|bfo:BRAFLDRAFT_67515|thyroid peroxidase [EC:1.11.1.8];K10789|3|1e-70|268|tgu:100228147|myeloperoxidase [EC:1.11.1.7] GO:0030312//external encapsulating structure;GO:0030312//external encapsulating structure GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding GO:0006909//phagocytosis;GO:0008152//metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006950//response to stress;GO:0006909//phagocytosis;GO:0008152//metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006950//response to stress 38952 838.00 0.01 1.665 7.37937836707126 Up 0.618181217804781 Jon66Ci jonah 66Ci K01310|1|3e-70|265|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|3e-69|261|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43194 366.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 CG14237 CG14237 - - - - 38046 783.78 37.145 37.615 0.0181400642764757 Up 0.0822216351868974 mRpL17 mitochondrial ribosomal protein L17, isoform B - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 34152 1311.63 32.115 20.645 -0.637454877930488 Down 0.625941091005151 CG17292 CG17292, isoform D K01046|1|4e-25|115|bta:515764|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 19836004 493.00 0.255 0.47 0.882163509706142 Up 0.153315281997094 - CG44574 - - - - 33881 6152.07 15.575 18.915 0.280298613138012 Up 0.410579844142121 Gef26 PDZ domain-containing guanine nucleotide exchange factor, isoform D K08018|1|0.0|2432|dme:Dmel_CG9491|Rap guanine nucleotide exchange factor (GEF) 2 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding GO:0042478//regulation of eye photoreceptor cell development;GO:0007243//intracellular protein kinase cascade;GO:0008360//regulation of cell shape;GO:0006929//substrate-dependent cell migration;GO:0007154//cell communication;GO:0019827//stem cell maintenance;GO:0009966//regulation of signal transduction;GO:0007292//female gamete generation;GO:0007484//imaginal disc-derived genitalia development;GO:0007472//wing disc morphogenesis;GO:0042478//regulation of eye photoreceptor cell development;GO:0007243//intracellular protein kinase cascade;GO:0008360//regulation of cell shape;GO:0006929//substrate-dependent cell migration;GO:0007154//cell communication;GO:0019827//stem cell maintenance;GO:0009966//regulation of signal transduction;GO:0007292//female gamete generation;GO:0007484//imaginal disc-derived genitalia development;GO:0007472//wing disc morphogenesis;GO:0042478//regulation of eye photoreceptor cell development;GO:0007243//intracellular protein kinase cascade;GO:0008360//regulation of cell shape;GO:0006929//substrate-dependent cell migration;GO:0007154//cell communication;GO:0019827//stem cell maintenance;GO:0009966//regulation of signal transduction;GO:0007292//female gamete generation;GO:0007484//imaginal disc-derived genitalia development;GO:0007472//wing disc morphogenesis 10178806 255.00 3.11 4.625 0.572538785273072 Up 0.377360982697134 CG42656 CG42656 - - GO:0003824//catalytic activity - 43012 3548.32 8.6 7.93 -0.117015793885482 Down 0.17434949148065 CG33095 CG33095, isoform B - - - - 14462627 502.00 0.255 0.095 -1.42449782852791 Down 0.140569277506274 318922 1342.00 0.675 0.57 -0.243925582886089 Down 0.0878681812178048 CG31735 CG31735, isoform C - - GO:0017022//myosin binding;GO:0017022//myosin binding - 50259 389.00 3.42 5.815 0.76578286658732 Up 0.473187161537445 CG14104 CG14104 - - - - 14462782 537.00 0.38 0.175 -1.11864449649862 Down 0.152522784308546 19835529 598.00 1.45 0.255 -2.50748374804344 Down 0.426958129705455 318911 851.97 38.195 31.87 -0.26118477235647 Down 0.442510896843218 CG31717 CG31717, isoform B K01112|1|7e-12|70.9|dre:402958| [EC:3.1.3.-] GO:0044464//cell part - - 32796 3904.50 37.175 45.62 0.295333704372357 Up 0.491051380266808 ari-1 ariadne, isoform F K11968|1|0.0|1042|dme:Dmel_CG5659|ariadne-1 - GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0016564//transcription repressor activity GO:0006350;GO:0006350;GO:0006350 32568 2622.00 7.455 7.895 0.0827309135767944 Up 0.128285563333774 CG8939 CG8939 K02427|1|1e-34|148|tca:664604|ribosomal RNA large subunit methyltransferase E [EC:2.1.1.-] GO:0031981//nuclear lumen GO:0005488//binding;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity GO:0006730//one-carbon metabolic process;GO:0000154//rRNA modification 32109 2161.46 16.83 14.25 -0.240073257390483 Down 0.36167613261128 rho-4 rhomboid-4, isoform B K02857|1|1e-87|324|ame:412319|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0004175//endopeptidase activity GO:0023060;GO:0023060 33960 6472.00 2.06 2.085 0.0174030462614451 Up 0.0440166424514595 l(2)k09022 lethal (2) k09022 - - - - 33864 712.00 42.975 42.44 -0.0180729834506585 Down 0.0835424646678114 Arpc4 Actin-related protein 2/3 complex, subunit 4 K05755|1|7e-90|329|dme:Dmel_CG5972|actin related protein 2/3 complex, subunit 4 GO:0043232 - GO:0065008;GO:0006909//phagocytosis;GO:0030030//cell projection organization;GO:0008154//actin polymerization or depolymerization 35100 4457.00 17.835 21.305 0.256480835711407 Up 0.400541540087175 bsf bicoid stability factor - - - - 33179 522.96 313.9 303.75 -0.0474206202016094 Down 0.160018491612733 CG11455 CG11455, isoform K K03938|1|2e-56|218|dya:Dyak_GE16615|NADH dehydrogenase (ubiquinone) Fe-S protein 5 [EC:1.6.5.3 1.6.99.3] - GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 37157 1843.36 27.665 27.565 -0.00522432235171315 Down 0.0547483819838859 List Lithium-inducible SLC6 transporter, isoform D K05336|1|1e-172|426|dme:Dmel_CG8850|solute carrier family 6 (neurotransmitter transporter), invertebrate - - - 42616 1590.00 12.13 13.005 0.100486848822481 Up 0.179401664245146 PSR phosphatidylserine receptor, isoform B - GO:0043231//intracellular membrane-bounded organelle - GO:0006915//apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0007275//multicellular organismal development 42491 2411.24 16.615 19.035 0.196168276870231 Up 0.331990490027737 Cortactin cortactin, isoform D K06106|1|0.0|931|dme:Dmel_CG3637|cortactin GO:0032991//macromolecular complex;GO:0043232;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0065008;GO:0007293//germarium-derived egg chamber formation;GO:0045807//positive regulation of endocytosis;GO:0007297//ovarian follicle cell migration 41524 6722.14 8.955 9.85 0.137430292357777 Up 0.207007000396249 pps protein partner of snf, isoform B K13179|1|8e-49|197|api:100167834|ATP-dependent RNA helicase DDX18 [EC:3.6.4.13];K11728|3|3e-10|68.9|bfo:BRAFLDRAFT_126069|nucleosome-remodeling factor subunit BPTF - - - 41455 2789.30 128.49 132.93 0.0490106495949031 Up 0.155956940958922 mfas midline fasciclin, isoform Q - GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane - - 41395 1319.00 10.57 10.41 -0.0220053080832659 Down 0.0657773081495179 CG14711 CG14711 K09228|1|9e-38|157|mmu:434377|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 39451 2348.00 0.305 0.425 0.478653598574816 Up 0.103982300884956 CG10969 CG10969 - - - - 12798240 257.42 70.07 73.115 0.0613705182311148 Up 0.172764496103553 CG43147 CG43147, isoform C - - - - 326254 1248.00 0.95 0.77 -0.303069067636046 Down 0.115902786950205 CG33099 CG33099 K06892|1|5e-37|155|spu:760899| - GO:0003824//catalytic activity GO:0008152//metabolic process 5740323 5506.00 15.285 15.705 0.0391073907649944 Up 0.103321886144499 CG34380 CG34380, isoform E K05125|1|2e-64|248|cel:F11D5.3|discoidin domain receptor family member 2 [EC:2.7.10.1] - GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0000166//nucleotide binding GO:0009987//cellular process 43133 949.86 4.47 4.57 0.0319193338747521 Up 0.0618808611808216 CG5948 CG5948, isoform B K00518|1|2e-115|415|dme:Dmel_CG5948|superoxide dismutase [EC:1.15.1.1];K04565|3|8e-32|137|aag:AaeL_AAEL014091|Cu/Zn superoxide dismutase [EC:1.15.1.1] - GO:0016209//antioxidant activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0006801//superoxide metabolic process 19835474 606.00 0.465 0.45 -0.0473057147783568 Down 0.0451063267732136 32470 2394.67 31.45 31.8 0.0159667484050664 Up 0.0786553955884295 Scamp scamp, isoform D K08823|1|1e-49|198|tgu:100219962|CDC-like kinase [EC:2.7.12.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0007613//memory;GO:0006887//exocytosis;GO:0007613//memory;GO:0006887//exocytosis 38077 1035.00 9.83 10.81 0.137103201394069 Up 0.214865935807687 CG3402 CG3402 - - GO:0005488//binding GO:0060026//convergent extension 14462798 712.00 0.735 0.82 0.157879659781719 Up 0.0746268656716418 41579 880.25 34.3 41.985 0.291665411233897 Up 0.477545898824462 CG10126 CG10126, isoform B K12042|1|4e-11|68.6|bfo:BRAFLDRAFT_106363|troponin C, skeletal muscle;K02183|2|1e-10|66.6|cbr:CBG08342|calmodulin - - - 37591 894.63 299.57 293.285 -0.0305898677976879 Down 0.115308413683793 CG2852 CG2852, isoform D K03768|1|3e-93|341|dme:Dmel_CG2852|peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 43691 1207.00 10.34 9.145 -0.177181110566218 Down 0.254721965394268 CG1542 CG1542 - GO:0031981//nuclear lumen - - 41213 901.00 0.61 0.675 0.146078259487945 Up 0.0705653150178312 CG9459 CG9459 K00680|1|6e-133|473|dme:Dmel_CG9459| [EC:2.3.1.-];K10250|5|2e-26|119|smm:Smp_010770.2|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane - - 38687 1605.00 1.235 0.17 -2.86090439033434 Down 0.415037643640206 CG6592 CG6592 K01310|1|2e-46|186|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|5|8e-37|154|dme:Dmel_CG31039| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43055 1334.00 3.125 0.2 -3.96578428466209 Down 0.634922731475366 CG13658 CG13658 - - - - 39817 934.00 81.49 160.68 0.979495430696968 Up 0.725828820499274 CG4842 CG4842 K00001|1|1e-33|143|dwi:Dwil_GK18290|alcohol dehydrogenase [EC:1.1.1.1];K00069|4|1e-32|140|gga:422567|15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0044281//small molecule metabolic process 32623 2376.33 25.2 29.895 0.246480477172935 Up 0.415962224276846 Arp2 Actin-related protein 2, isoform C K10354|1|5e-99|362|dre:408256|actin, alpha skeletal muscle;K05692|3|6e-99|362|smm:Smp_046590|actin beta/gamma 1;K12314|5|8e-99|361|xtr:394698|actin, alpha cardiac muscle GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0032559;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0032559;GO:0005198//structural molecule activity GO:0030832//regulation of actin filament length;GO:0030832//regulation of actin filament length 12797884 4774.00 0.08 0.09 0.169925001442312 Up 0.045667679302602 42917 750.00 0.315 0.255 -0.304854581528421 Down 0.0747259278827103 CG13616 CG13616, isoform B - - - - 36636 790.00 51.35 47.985 -0.0977807833687274 Down 0.240721172896579 AttA Attacin-A - GO:0044421//extracellular region part - GO:0042742//defense response to bacterium 19835399 332.00 0.01 0.185 4.20945336562895 Up 0.199412230880993 38286 1402.26 201.7 200.07 -0.0117062290310214 Down 0.0697728173292828 CG1275 CG1275, isoform D K08360|1|2e-132|472|dme:Dmel_CG1275|cytochrome b-561 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 39877 1520.00 81.485 68.89 -0.24223993017934 Down 0.452119931316867 Int6 Int6 homologue K03250|1|0.0|880|dsi:Dsim_GD12442|translation initiation factor eIF-3 subunit 6 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding GO:0006909//phagocytosis;GO:0006412//translation 40202 1235.00 0.16 0.04 -2 Down 0.1267335886937 obst-J obstructor-J K01873|1|2e-12|73.9|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 39953 1517.62 0.72 0.595 -0.275107238134369 Down 0.0949346189406948 CG6333 CG6333, isoform B - - - - 40269 947.00 13.73 13.15 -0.0622688259674361 Down 0.129540351340642 CG5969 CG5969 K00683|1|1e-15|83.6|dme:Dmel_CG5976|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030134//ER to Golgi transport vesicle;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016787//hydrolase activity;GO:0016755 GO:0019538//protein metabolic process 14462918 1361.00 0.145 0.065 -1.15754127698648 Down 0.0982366926429798 19835089 889.00 21.695 27.09 0.320397807385272 Up 0.476555276713776 43105 4076.30 46.915 47.83 0.027866526030718 Up 0.105237088891824 LpR2 lipophorin receptor 2, isoform I K12473|1|1e-177|624|rno:300438|low-density lipoprotein receptor GO:0044464//cell part;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0016020//membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0030169//low-density lipoprotein particle binding GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis;GO:0016125//sterol metabolic process;GO:0006897//endocytosis 31714 2003.00 0.41 0.36 -0.187627003175772 Down 0.0653810593052437 CG15332 CG15332 - - - - 32587 1663.61 33.72 39.335 0.222209047324013 Up 0.403348302734117 caz cabeza, isoform E K13098|1|4e-95|348|dme:Dmel_CG3606|RNA-binding protein FUS GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding GO:0016070//RNA metabolic process;GO:0010467//gene expression 32991 1114.03 10.105 10.75 0.0892673380970873 Up 0.154735173689077 Alr augmenter of liver regeneration, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor GO:0008152//metabolic process;GO:0019725//cellular homeostasis 36103 593.00 32.315 31.22 -0.0497334543000301 Down 0.138654074758949 CG12895 CG12895, isoform B - GO:0043231//intracellular membrane-bounded organelle - GO:0018065//protein-cofactor linkage;GO:0022904//respiratory electron transport chain 41085 3862.94 6.49 5.69 -0.189789825692557 Down 0.218002905824858 neur neuralized, isoform E K01931|1|0.0|1217|dme:Dmel_CG11988|protein neuralized GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity GO:0033036;GO:0042478//regulation of eye photoreceptor cell development;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051301//cell division;GO:0007635//chemosensory behavior;GO:0002118//aggressive behavior;GO:0019827//stem cell maintenance;GO:0001709//cell fate determination;GO:0007472//wing disc morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0033036;GO:0042478//regulation of eye photoreceptor cell development;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051301//cell division;GO:0007635//chemosensory behavior;GO:0002118//aggressive behavior;GO:0019827//stem cell maintenance;GO:0001709//cell fate determination;GO:0007472//wing disc morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0033036;GO:0042478//regulation of eye photoreceptor cell development;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051301//cell division;GO:0007635//chemosensory behavior;GO:0002118//aggressive behavior;GO:0019827//stem cell maintenance;GO:0001709//cell fate determination;GO:0007472//wing disc morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0033036;GO:0042478//regulation of eye photoreceptor cell development;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051301//cell division;GO:0007635//chemosensory behavior;GO:0002118//aggressive behavior;GO:0019827//stem cell maintenance;GO:0001709//cell fate determination;GO:0007472//wing disc morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0033036;GO:0042478//regulation of eye photoreceptor cell development;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0003006//developmental process involved in reproduction;GO:0051301//cell division;GO:0007635//chemosensory behavior;GO:0002118//aggressive behavior;GO:0019827//stem cell maintenance;GO:0001709//cell fate determination;GO:0007472//wing disc morphogenesis;GO:0008593//regulation of Notch signaling pathway 32100 6736.00 9.76 10.05 0.042242448503405 Up 0.0919627526086382 RpII215 RNA polymerase II 215kD subunit K03006|1|0.0|3021|dme:Dmel_CG1554|DNA-directed RNA polymerase II subunit A [EC:2.7.7.6] GO:0016591//DNA-directed RNA polymerase II, holoenzyme GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 40091 828.03 15.965 15.87 -0.00861042473491156 Down 0.053625676925109 mRpL21 mitochondrial ribosomal protein L21, isoform C - GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression 39810 2559.00 8.23 7.52 -0.130159768743988 Down 0.184519878483688 CG4925 CG4925 K10352|1|9e-16|85.9|rno:29605|myosin heavy chain - - - 39376 1101.00 8.035 8.28 0.0433327438242316 Up 0.0868445383700964 CG11560 CG11560 - - GO:0003676//nucleic acid binding - 39145 4623.12 77.9 80.92 0.0548729916092513 Up 0.153447364945186 CG42268 CG42268, isoform M - - - - 38550 686.00 5.565 2.665 -1.06224615458278 Down 0.528232730154537 CG15023 CG15023, isoform D - - - - 40080 2062.00 32.695 43.335 0.406462681339153 Up 0.560659093910976 CG6812 CG6812 K03351|1|4e-62|239|smm:Smp_136960|anaphase-promoting complex subunit 4 GO:0044464//cell part GO:0015075//ion transmembrane transporter activity;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0006811//ion transport 35130 2276.00 5.39 2.87 -0.909234536076818 Down 0.493957205124818 Grip71 Grip71 - - - - 44030 5690.80 31.7 30.905 -0.0366425753206993 Down 0.11851142517501 msn misshapen, isoform I K08282|1|5e-165|582|cel:ZC504.4|non-specific serine/threonine protein kinase [EC:2.7.11.1];K04407|3|2e-152|541|gga:418714|mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0030695//GTPase regulator activity;GO:0032559;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0030695//GTPase regulator activity;GO:0032559;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0030695//GTPase regulator activity;GO:0032559;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0030695//GTPase regulator activity;GO:0032559;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0030695//GTPase regulator activity;GO:0032559;GO:0008349//MAP kinase kinase kinase kinase activity GO:0008360//regulation of cell shape;GO:0040023//establishment of nucleus localization;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade;GO:0008360//regulation of cell shape;GO:0040023//establishment of nucleus localization;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade;GO:0008360//regulation of cell shape;GO:0040023//establishment of nucleus localization;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade;GO:0008360//regulation of cell shape;GO:0040023//establishment of nucleus localization;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade;GO:0008360//regulation of cell shape;GO:0040023//establishment of nucleus localization;GO:0009886//post-embryonic morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0001738//morphogenesis of a polarized epithelium;GO:0000165//MAPK cascade 38281 1631.00 0.42 0.88 1.06711419585854 Up 0.238376700567957 CG15878 CG15878 - - - - 38178 5440.19 26.63 28.09 0.0770041959157841 Up 0.185279355435213 CG7852 CG7852, isoform C - - - - 42134 702.00 13.265 14.395 0.117943113334739 Up 0.212059173160745 CG14321 CG14321 - - - - 39995 1421.20 106.6 81.085 -0.394700479542304 Down 0.581891427816669 Tsp74F tetraspanin 74F, isoform B K06537|1|1e-33|144|tgu:100224798|CD151 antigen;K06497|2|2e-33|143|nve:NEMVE_v1g236446|CD63 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 38300 3790.60 60.315 61.04 0.0172381253130137 Up 0.0864152687887994 CG1317 CG1317, isoform D K10661|1|0.0|1137|dme:Dmel_CG1317|E3 ubiquitin-protein ligase MARCH6 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 38214 4073.00 4.6 6.02 0.388129625815327 Up 0.341500462290318 CG7991 CG7991, isoform C - - - - 32083 4483.76 67.275 89.585 0.413186703590902 Up 0.588033284902919 dlg1 discs large 1, isoform U K12075|1|3e-37|157|aga:AgaP_AGAP000255|discs large protein;K12076|2|1e-19|99.0|bta:785291|disks large protein 1 GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0043232;GO:0033267//axon part;GO:0045202//synapse GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0070851//growth factor receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization;GO:0030709//border follicle cell delamination;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0001700//embryonic development via the syncytial blastoderm;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007619//courtship behavior;GO:0042331//phototaxis;GO:0007399//nervous system development;GO:0051293//establishment of spindle localization 43156 1305.00 2.985 3.235 0.116034780727703 Up 0.109529784704795 E(spl)m3-HLH enhancer of split m3, helix-loop-helix K09090|1|2e-97|356|dme:Dmel_CG8346|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0001654//eye development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway 43349 1400.00 556.855 528.3 -0.0759443018505094 Down 0.224970281336679 RpL4 ribosomal protein L4 K02930|1|0.0|659|dme:Dmel_CG5502|large subunit ribosomal protein L4e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 40694 2711.26 56.81 55.83 -0.0251043468613829 Down 0.10622771100251 sec23 Sec23 ortholog, isoform H K14006|1|0.0|1511|dme:Dmel_CG1250|protein transport protein SEC23 GO:0012507//ER to Golgi transport vesicle membrane;GO:0044431//Golgi apparatus part;GO:0012507//ER to Golgi transport vesicle membrane;GO:0044431//Golgi apparatus part GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity GO:0048079;GO:0034613//cellular protein localization;GO:0007163//establishment or maintenance of cell polarity;GO:0065008;GO:0016337//cell-cell adhesion;GO:0008363//larval chitin-based cuticle development;GO:0015031//protein transport;GO:0006996//organelle organization;GO:0048193//Golgi vesicle transport;GO:0035148//tube formation;GO:0031345//negative regulation of cell projection organization;GO:0003330//regulation of extracellular matrix constituent secretion;GO:0048079;GO:0034613//cellular protein localization;GO:0007163//establishment or maintenance of cell polarity;GO:0065008;GO:0016337//cell-cell adhesion;GO:0008363//larval chitin-based cuticle development;GO:0015031//protein transport;GO:0006996//organelle organization;GO:0048193//Golgi vesicle transport;GO:0035148//tube formation;GO:0031345//negative regulation of cell projection organization;GO:0003330//regulation of extracellular matrix constituent secretion 318169 4045.00 0.165 0.255 0.628031222613042 Up 0.094439307885352 CG32719 CG32719 - GO:0044464//cell part GO:0046914//transition metal ion binding - 32145 1481.00 20.895 19.895 -0.0707518596286717 Down 0.15998547087571 CG11802 CG11802 - - - - 37363 947.00 0.64 0.595 -0.105182236692056 Down 0.0557059833575485 CG9236 CIB2 ortholog K06268|1|3e-25|114|bfo:BRAFLDRAFT_92996|protein phosphatase 3, regulatory subunit - - - 34943 1276.00 0.805 0.935 0.21597758177302 Up 0.0929863954563466 CG18063 CG18063, isoform E - - - - 19835561 1546.00 0.055 0.195 1.82597060022495 Up 0.13380002641659 39910 1198.00 8.675 10.295 0.247008167166631 Up 0.314621582353718 beg bad egg K00645|1|0.0|710|dme:Dmel_CG7842|[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] - GO:0004312//fatty acid synthase activity GO:0006631//fatty acid metabolic process 43016 1584.14 54.68 50.58 -0.112446205942822 Down 0.261392154272883 vig2 vig2, isoform D K13199|1|7e-155|547|dsi:Dsim_GD21176|plasminogen activator inhibitor 1 RNA-binding protein GO:0005700//polytene chromosome;GO:0005700//polytene chromosome;GO:0005700//polytene chromosome;GO:0005700//polytene chromosome - GO:0034968//histone lysine methylation;GO:0034968//histone lysine methylation;GO:0034968//histone lysine methylation;GO:0034968//histone lysine methylation 10178823 562.00 0.075 0.245 1.70781924850669 Up 0.148197067758552 CG42778 CG42778 - - - - 10178807 3175.00 2.47 2.405 -0.0384741478146353 Down 0.0559371285167085 42901 2267.00 0.375 0.59 0.65382435886596 Up 0.14040417382116 CG6432 CG6432, isoform B K01908|1|0.0|1341|dme:Dmel_CG6432|propionyl-CoA synthetase [EC:6.2.1.17] - - - 19836049 686.00 0.01 0.2 4.32192809488736 Up 0.209648659358077 33897 1918.00 10.74 11.015 0.0364755017154707 Up 0.0909391097609299 Fic Fic domain-containing protein - GO:0031224//intrinsic to membrane GO:0070566//adenylyltransferase activity GO:0018175 5740216 829.00 0.495 0.905 0.870489267003596 Up 0.215757495707304 CG34244 CG34244, isoform B - - - - 14462352 201.00 1.27 0.565 -1.16850572435698 Down 0.300059437326641 39577 540.00 1.06 0.595 -0.833102691255256 Down 0.228701624620262 CG13482 CG13482 - - - - 38517 828.00 58.745 55.37 -0.0853615420275711 Down 0.224243825122177 CG1265 CG1265 K09660|1|2e-15|82.8|nvi:100119954|mannose-P-dolichol utilization defect 1 - - - 42096 1573.00 0.055 0.06 0.125530882083859 Up 0.0444459120327566 CG5863 CG5863 K01379|1|0.0|770|dme:Dmel_CG5863|cathepsin D [EC:3.4.23.5];K06002|1|0.0|770|dme:Dmel_CG5863|pepsin A [EC:3.4.23.1] - - - 41586 1716.00 0.625 0.3 -1.05889368905357 Down 0.196572447497028 Cyp304a1 Cyp304a1 K00517|1|0.0|1005|dme:Dmel_CG7241| [EC:1.14.-.-];K07422|2|3e-50|199|dre:556280|cytochrome P450, family 2, subfamily U;K07412|4|3e-49|196|mmu:13088|cytochrome P450, family 2, subfamily B [EC:1.14.14.1] - - - 43020 1832.00 6.51 7.845 0.269115903802462 Up 0.301347246070532 danr distal antenna-related - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0001654//eye development;GO:0010468//regulation of gene expression;GO:0007389//pattern specification process 45840 8402.33 32.865 35.505 0.111470221744392 Up 0.248778232730155 cpo couch potato, isoform Y - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0032501//multicellular organismal process;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior;GO:0032501//multicellular organismal process;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior;GO:0032501//multicellular organismal process;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior;GO:0032501//multicellular organismal process;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior;GO:0032501//multicellular organismal process;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior;GO:0032501//multicellular organismal process;GO:0007267//cell-cell signaling;GO:0007635//chemosensory behavior 117339 1215.00 0.36 0.34 -0.082462160191973 Down 0.0463611147800819 Gr94a gustatory receptor 94a K08471|1|2e-12|73.9|dme:Dmel_CG13417|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 34578 1330.11 2.56 2.58 0.0112272554232541 Up 0.0432901862369568 Mst33A Mst33A, isoform C - - - - 12797875 570.46 0.01 0.635 5.98868468677217 Up 0.405263505481442 CG43401 CG43401, isoform B - - - - 32278 6253.67 17.67 21.19 0.262081547820552 Up 0.401796328094043 HDAC4 HDAC4, isoform J K11406|1|0.0|1890|dya:Dyak_GE16165|histone deacetylase 4/5 [EC:3.5.1.98] GO:0016585//chromatin remodeling complex;GO:0016585//chromatin remodeling complex;GO:0016585//chromatin remodeling complex GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0010468//regulation of gene expression;GO:0006325//chromatin organization;GO:0010468//regulation of gene expression;GO:0006325//chromatin organization;GO:0010468//regulation of gene expression;GO:0006325//chromatin organization 35565 1292.71 9.695 9.795 0.0148045941607944 Up 0.0547483819838859 Dpit47 DNA polymerase interacting tpr containing protein of 47kD, isoform B K09527|1|7e-10|65.5|smm:Smp_138680.2|DnaJ homolog subfamily C member 7;K09553|5|4e-06|52.8|tca:655405|stress-induced-phosphoprotein 1 - - - 43000 1733.89 60.035 41.485 -0.533214041306295 Down 0.624950468894466 CG11791 CG11791, isoform D - - - - 40581 4186.92 82.755 86.74 0.0678509620088533 Up 0.192609959054286 Karybeta3 karyopherin beta 3, isoform B - GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008565//protein transporter activity GO:0015031//protein transport 40755 2629.00 2.155 3.19 0.565868554675771 Up 0.317098137630432 Osi24 osiris 24 K04209|1|2e-58|227|tca:656041|neuropeptide Y receptor, invertebrate - - - 261621 1183.69 92.36 100.635 0.123792071299128 Up 0.290252278430855 CG31706 CG31706, isoform B - - - - 36754 1472.00 6.15 7.405 0.267913325062246 Up 0.292992999603751 CG8366 CG8366 - - GO:0003676//nucleic acid binding;GO:0016788//hydrolase activity, acting on ester bonds - 41551 1443.20 102.335 98.655 -0.0528355752387301 Down 0.154933298111214 Snx3 sorting nexin 3, isoform B - - - - 3354941 2630.30 121.55 155.765 0.357821206534996 Up 0.571721040813631 CG40178 CG40178, isoform C K09536|1|3e-80|300|cel:C56C10.13|DnaJ homolog subfamily C member 16 - GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis;GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis 37548 3013.13 30.785 22.925 -0.425305834732671 Down 0.550818914278167 wdp windpipe, isoform E - GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 19835079 380.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 42798 1484.00 0.31 0.185 -0.744742944757925 Down 0.109859992075023 CG10300 CG10300 K10693|1|2e-14|80.9|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0044464//cell part - GO:0051234//establishment of localization 14462828 262.00 0.355 0.4 0.17218097538268 Up 0.0647866860388324 43757 1409.09 27.215 28.405 0.0617428669165967 Up 0.155131422533351 ferrochelatase ferrochelatase, isoform C K01772|1|0.0|438|dme:Dmel_CG2098|ferrochelatase [EC:4.99.1.1] GO:0019866//organelle inner membrane;GO:0015630//microtubule cytoskeleton;GO:0019866//organelle inner membrane;GO:0015630//microtubule cytoskeleton;GO:0019866//organelle inner membrane;GO:0015630//microtubule cytoskeleton GO:0016829//lyase activity;GO:0016829//lyase activity;GO:0016829//lyase activity GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006779//porphyrin-containing compound biosynthetic process 42896 7746.21 16.25 17.04 0.0684856174226589 Up 0.150211332716946 crb crumbs, isoform D K02599|1|2e-174|614|spu:575027|Notch GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0042995//cell projection;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0042995//cell projection GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding GO:0033036;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0045217//cell-cell junction maintenance;GO:0007292//female gamete generation;GO:0035090//maintenance of apical/basal cell polarity;GO:0030859//polarized epithelial cell differentiation;GO:0007431//salivary gland development;GO:0042051//compound eye photoreceptor development;GO:0060541//respiratory system development;GO:0048598//embryonic morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0033036;GO:0007043//cell-cell junction assembly;GO:0008283//cell proliferation;GO:0045217//cell-cell junction maintenance;GO:0007292//female gamete generation;GO:0035090//maintenance of apical/basal cell polarity;GO:0030859//polarized epithelial cell differentiation;GO:0007431//salivary gland development;GO:0042051//compound eye photoreceptor development;GO:0060541//respiratory system development;GO:0048598//embryonic morphogenesis;GO:0008593//regulation of Notch signaling pathway 33585 508.00 2.15 2.22 0.046223016760646 Up 0.0588099326376965 CG15418 CG15418 K03909|1|4e-10|63.9|mmu:21788|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 35312 527.96 0.44 0.57 0.373458395527444 Up 0.10484084004755 CG15130 CG15130, isoform C - - - - 5740226 573.45 0.95 1.33 0.485426827170242 Up 0.18617091533483 CG34264 CG34264, isoform D - - - - 246543 2935.00 0.245 0.625 1.35107444054688 Up 0.224673094703474 Vha100-3 vacuolar H[+] ATPase 100kD subunit 3 K02154|1|0.0|1794|dme:Dmel_CG30329|V-type H+-transporting ATPase subunit I [EC:3.6.3.14] GO:0016469//proton-transporting two-sector ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006754//ATP biosynthetic process 34249 2133.98 0.58 1.155 0.993768046288485 Up 0.260797781006472 CG17005 CG17005, isoform E - - - - 33592 364.26 1391.615 711.335 -0.968159079040613 Down 0.734050984017963 CG16712 CG16712, isoform B K06238|1|9e-10|61.6|ptr:460045|collagen, type VI, alpha;K03909|4|6e-09|58.9|mmu:21788|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 14462560 351.00 0.5 0.28 -0.83650126771712 Down 0.151334037775723 326238 1645.00 0.635 0.29 -1.13070369164459 Down 0.204728569541672 CG32750 CG32750 K01435|1|2e-87|323|dpo:Dpse_GA17117|biotinidase [EC:3.5.1.12];K08069|3|3e-35|149|ssc:397246|pantetheine hydrolase [EC:3.5.1.92] GO:0044425//membrane part GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0008152//metabolic process 14462644 727.00 0.46 1.22 1.40717538150587 Up 0.32112666754722 31364 4051.41 39.01 36.64 -0.0904244949276184 Down 0.215064060229824 Fas2 fasciclin 2, isoform H K06491|1|0.0|1513|dme:Dmel_CG3665|neural cell adhesion molecule GO:0043005//neuron projection;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0043005//neuron projection;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0043005//neuron projection;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0045202//synapse GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0048741//skeletal muscle fiber development;GO:0048638//regulation of developmental growth;GO:0007613//memory;GO:0007409//axonogenesis;GO:0030534//adult behavior;GO:0016337//cell-cell adhesion;GO:0008306//associative learning;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035151//regulation of tube size, open tracheal system;GO:0007420//brain development;GO:0048592//eye morphogenesis;GO:0008037//cell recognition;GO:0048805;GO:0043062//extracellular structure organization;GO:0048741//skeletal muscle fiber development;GO:0048638//regulation of developmental growth;GO:0007613//memory;GO:0007409//axonogenesis;GO:0030534//adult behavior;GO:0016337//cell-cell adhesion;GO:0008306//associative learning;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035151//regulation of tube size, open tracheal system;GO:0007420//brain development;GO:0048592//eye morphogenesis;GO:0008037//cell recognition;GO:0048805;GO:0043062//extracellular structure organization;GO:0048741//skeletal muscle fiber development;GO:0048638//regulation of developmental growth;GO:0007613//memory;GO:0007409//axonogenesis;GO:0030534//adult behavior;GO:0016337//cell-cell adhesion;GO:0008306//associative learning;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035151//regulation of tube size, open tracheal system;GO:0007420//brain development;GO:0048592//eye morphogenesis;GO:0008037//cell recognition;GO:0048805;GO:0043062//extracellular structure organization 3885570 594.00 12.495 14.15 0.179451151632541 Up 0.283747193237353 CG34015 CG34015 K10863|1|4e-07|54.3|dvi:Dvir_GJ22721|aprataxin [EC:3.-.-.-] - - - 19834988 828.00 0.65 0.225 -1.53051471669878 Down 0.243098665962224 19835170 1073.00 0.075 0.475 2.66296501272243 Up 0.255778628978999 318824 41692.27 9.815 10.43 0.0876789850535944 Up 0.151664245145952 dp dumpy, isoform Z - - - - 38829 1480.00 0.185 0.145 -0.351472370501377 Down 0.0666688680491349 CG18417 CG18417 K01291|1|2e-58|226|tgu:100222062|carboxypeptidase B [EC:3.4.17.2];K01290|3|3e-57|223|dsi:Dsim_GD22481|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 318751 1694.00 0.965 1.335 0.468238894419474 Up 0.181977281732928 CG31467 CG31467 - - - - 37339 1584.00 14.93 15.97 0.0971501472766912 Up 0.190265486725664 DMAP1 DMAP1 K11324|1|0.0|816|dme:Dmel_CG11132|DNA methyltransferase 1-associated protein 1 - - - 44008 1493.00 89.025 58.445 -0.607130923859703 Down 0.659027869502047 Hex-C hexokinase C K00844|1|0.0|871|dme:Dmel_CG8094|hexokinase [EC:2.7.1.1] - GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032559 GO:0006007//glucose catabolic process 5740448 148.00 0.01 0.435 5.44294349584873 Up 0.33109893012812 37021 3503.00 13.9 13.38 -0.0550067669694091 Down 0.125280676264694 CG4996 CG4996 - - - - 33712 1153.00 10.275 8.53 -0.268520747250755 Down 0.333674547615903 CG3756 CG3756 K03027|1|0.0|650|dme:Dmel_CG3756|DNA-directed RNA Polymerase III subunit C5 [EC:2.7.7.6] GO:0044451//nucleoplasm part;GO:0044452;GO:0015630//microtubule cytoskeleton GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0006351//transcription, DNA-dependent 34007 3162.53 3.545 3.745 0.0791800912192351 Up 0.0903117157574957 Wnt4 Wnt oncogene analog 4, isoform B K01064|1|2e-61|238|xtr:100125200|wingless-type MMTV integration site family, member 9 GO:0016020//membrane;GO:0031012//extracellular matrix GO:0005102//receptor binding;GO:0060089 GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008406//gonad development;GO:0048870//cell motility;GO:0001736//establishment of planar polarity;GO:0007044//cell-substrate junction assembly;GO:0003002//regionalization;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0007431//salivary gland development 46000 1342.00 0.06 0.07 0.222392421336448 Up 0.0461960110949676 scw screw, isoform B K04669|1|0.0|793|dme:Dmel_CG31695|TGF-beta receptor, other - GO:0016564//transcription repressor activity;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity GO:0051239;GO:0003002//regionalization;GO:0010004//gastrulation involving germ band extension;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0045165//cell fate commitment;GO:0007268//synaptic transmission;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 34209 920.00 0.595 0.615 0.0476967420312965 Up 0.0451063267732136 CG9483 CG9483 - - - - 41595 1416.53 4.035 6.735 0.739109272184522 Up 0.490390965526351 yellow-f yellow-f, isoform C - - - - 12798301 678.00 0.885 1.91 1.10982327795275 Up 0.354708757099458 CG43235 CG43235 - - - - 43416 1556.00 1.505 0.735 -1.03394733192334 Down 0.308512746004491 CG11828 CG11828 K00472|1|0.0|999|dme:Dmel_CG11828|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 36357 1736.33 37.78 33.045 -0.19319070596633 Down 0.367025492008982 CG8520 CG8520, isoform B K06916|1|0.0|899|dme:Dmel_CG8520| - GO:0032559;GO:0032559 - 35550 1762.00 0.29 0.13 -1.15754127698648 Down 0.137102100118875 CG17994 CG17994 - - - - 39695 1043.34 1.405 1.34 -0.0683371297631536 Down 0.0583476423193766 CG13449 CG13449, isoform B - - - - 170876 887.00 1.185 2.11 0.832355939808926 Up 0.319937921014397 Pif2 PFTAIRE-interacting factor 2 - - - - 34342 1182.00 5.525 4.965 -0.15418074675042 Down 0.173028661999736 CG13133 CG13133 K04455|1|5e-09|62.4|mcc:715615|heat shock 27kDa protein 1;K09542|3|1e-08|61.2|gga:396089|crystallin, alpha B GO:0015630//microtubule cytoskeleton - GO:0010259//multicellular organismal aging 33066 1409.00 0.355 0.815 1.1989810347264 Up 0.242174085325584 CG1314 CG1314 - GO:0044464//cell part GO:0046914//transition metal ion binding - 36839 2103.00 0.57 0.605 0.0859732231098528 Up 0.0537247391361775 CG7848 CG7848 K00029|1|0.0|1199|dme:Dmel_CG7848|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] - GO:0016615//malate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0043169//cation binding GO:0043648//dicarboxylic acid metabolic process 34159 526.00 39.98 37.935 -0.0757489343602327 Down 0.196308281600845 l(2)k12914 lethal (2) k12914 K12668|1|4e-51|199|dya:Dyak_GE11027|oligosaccharyltransferase complex subunit epsilon GO:0016020//membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0043066//negative regulation of apoptotic process 37099 468.00 27.45 135.55 2.30394705883251 Up 0.794577994980848 IM23 immune induced molecule 23 - - - - 40285 3909.00 5.98 4.67 -0.356722934488443 Down 0.325320301149122 knrl knirps-like K08706|1|0.0|858|dme:Dmel_CG4761|nuclear receptor subfamily 0 group A GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0007067//mitosis;GO:0035150//regulation of tube size;GO:0006351//transcription, DNA-dependent;GO:0007424//open tracheal system development 32314 1535.33 911.6 611.94 -0.575010719309386 Down 0.67388720116233 up upheld, isoform T K12046|1|4e-136|484|dme:Dmel_CG7107|troponin T, fast skeletal muscle GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis;GO:0031032//actomyosin structure organization;GO:0009888//tissue development;GO:0007015//actin filament organization;GO:0010927;GO:0006875//cellular metal ion homeostasis 4379865 384.00 4.855 6.24 0.362074733443056 Up 0.333146215823537 BG642167 BG642167 - - - - 39870 623.00 108.015 150.725 0.480687056589296 Up 0.629144102496368 PGRP-SB1 PGRP-SB1 K01446|1|2e-98|357|dme:Dmel_CG9681|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane;GO:0015630//microtubule cytoskeleton GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0002376//immune system process;GO:0006950//response to stress 19835758 1498.00 29.845 34.83 0.222841219136919 Up 0.397074362699775 35588 6126.39 47.11 56.805 0.269984589937655 Up 0.47127195879012 Epac exchange protein directly activated by cAMP ortholog, isoform G K08282|1|0.0|1815|dme:Dmel_CG34392|non-specific serine/threonine protein kinase [EC:2.7.11.1];K04351|3|0.0|853|bta:537312|Rap guanine nucleotide exchange factor (GEF) 4 GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0019887//protein kinase regulator activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0019887//protein kinase regulator activity GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0009966//regulation of signal transduction;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0009966//regulation of signal transduction 33553 1863.57 9.38 9.345 -0.00539325877021859 Down 0.0472856954167217 CG15412 CG15412, isoform C - - - - 33981 743.00 90.51 73.06 -0.30899544350584 Down 0.523675868445384 smt3 smt3 K12160|1|1e-46|186|dsi:Dsim_GD22523|small ubiquitin-related modifier GO:0031981//nuclear lumen;GO:0000777//condensed chromosome kinetochore;GO:0000794//condensed nuclear chromosome GO:0005488//binding GO:0006909//phagocytosis;GO:0046578//regulation of Ras protein signal transduction;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0003006//developmental process involved in reproduction;GO:0006605//protein targeting;GO:0043412//macromolecule modification;GO:0003002//regionalization;GO:0043405//regulation of MAP kinase activity;GO:0009060//aerobic respiration 37073 2241.00 16.3 17.3 0.0859000734056469 Up 0.17956676793026 adp adipose, isoform B K11807|1|0.0|1300|dme:Dmel_CG5124|WD and tetratricopeptide repeats protein 1 - - - 40652 4325.94 20.63 28.53 0.467735925695235 Up 0.564885748249901 CG14669 CG14669, isoform C K07851|1|2e-32|141|dre:100004647|Ras-like, family 10, member B GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction 32641 3429.00 0.03 0.04 0.415037499278844 Up 0.0473847576277902 CG15865 CG15865 - - - - 37546 4469.92 5.145 8.23 0.677721353527657 Up 0.500825518425571 dve defective proventriculus, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043565//sequence-specific DNA binding GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0007472//wing disc morphogenesis;GO:0010468//regulation of gene expression;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0006351//transcription, DNA-dependent 40485 483.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 CG14452 CG14452 - - - - 44238 2675.09 3.19 3.375 0.0813310781733239 Up 0.088693699643376 sip1 septin interacting protein 1, isoform B K13103|1|0.0|1606|dme:Dmel_CG7238|tuftelin-interacting protein 11 GO:0005681//spliceosomal complex;GO:0031012//extracellular matrix GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007635//chemosensory behavior;GO:0000377;GO:0010468//regulation of gene expression 19834753 924.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 41045 1999.00 22.73 22.46 -0.0172397564172466 Down 0.0745278034605732 CG8223 CG8223 K11291|1|2e-46|187|aag:AaeL_AAEL005904|nuclear autoantigenic sperm protein - - - 34142 888.00 10.375 10.715 0.0465205135548982 Up 0.102100118874653 CG7787 CG7787 - - GO:0046914//transition metal ion binding;GO:0030695//GTPase regulator activity GO:0035556//intracellular signal transduction 34699 4489.42 60.5 29.12 -1.05492478685062 Down 0.717375511821424 CG9934 CG9934, isoform B K10597|1|0.0|2253|dme:Dmel_CG9934|ubiquitin conjugation factor E4 B [EC:6.3.2.19] GO:0043234//protein complex;GO:0043234//protein complex GO:0005488//binding;GO:0004842//ubiquitin-protein ligase activity;GO:0005488//binding;GO:0004842//ubiquitin-protein ligase activity GO:0019941//modification-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation 3772436 605.00 0.205 0.45 1.13430109171159 Up 0.167811385550125 CG33773 CG33773 K09255|1|1e-20|99.0|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|9e-12|69.7|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 41872 975.59 18.015 19.83 0.138486025802058 Up 0.262812045964866 CG6171 CG6171, isoform B K13295|1|2e-12|73.6|mmu:72103|aprataxin and PNK-like factor [EC:4.2.99.18] - - - 38023 1669.79 82.725 58.825 -0.491893971088241 Down 0.621054021925769 Vdup1 vitamin D[[3]] up-regulated protein 1, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0050877//neurological system process;GO:0023060;GO:0050877//neurological system process;GO:0023060;GO:0050877//neurological system process;GO:0023060;GO:0050877//neurological system process;GO:0023060 40628 1865.72 240.8 217.075 -0.149641808258047 Down 0.352001056663585 CG12163 CG12163, isoform C K01373|1|1e-67|257|dse:Dsec_GM10654|cathepsin F [EC:3.4.22.41] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0004866//endopeptidase inhibitor activity;GO:0004175//endopeptidase activity;GO:0004866//endopeptidase inhibitor activity;GO:0004175//endopeptidase activity;GO:0004866//endopeptidase inhibitor activity GO:0012501//programmed cell death;GO:0019538//protein metabolic process;GO:0012501//programmed cell death;GO:0019538//protein metabolic process;GO:0012501//programmed cell death;GO:0019538//protein metabolic process 19835374 1588.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 39675 978.36 93.55 126.515 0.435498886757375 Up 0.610421344604412 Eip71CD Ecdysone-induced protein 28/29kD, isoform G K07304|1|5e-132|470|dme:Dmel_CG7266|peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] - GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor GO:0048102//autophagic cell death;GO:0043412//macromolecule modification;GO:0048102//autophagic cell death;GO:0043412//macromolecule modification;GO:0048102//autophagic cell death;GO:0043412//macromolecule modification;GO:0048102//autophagic cell death;GO:0043412//macromolecule modification 318887 2128.73 0.635 0.865 0.445943540864559 Up 0.139776779817726 CG31693 CG31693, isoform B - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006842//tricarboxylic acid transport;GO:0006842//tricarboxylic acid transport 37571 2099.00 7.05 8.36 0.245879684794727 Up 0.290945713908334 CG4610 CG4610 K03495|1|0.0|1211|dme:Dmel_CG4610|glucose inhibited division protein A GO:0044424//intracellular part GO:0030554//adenyl nucleotide binding GO:0002097 19835574 582.00 40.945 48.68 0.249641880181045 Up 0.443666622639017 19835990 962.00 0.44 0.675 0.617383978413534 Up 0.148923523973055 35109 3660.10 7.485 7.885 0.0751084387320937 Up 0.123464535728437 CG15160 CG15160, isoform C - - - - 39536 4550.00 22.22 21.895 -0.0212573669364407 Down 0.0774666490556069 Gl glued K04648|1|0.0|2162|dme:Dmel_CG9206|dynactin 1 GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0005875//microtubule associated complex;GO:0005876//spindle microtubule;GO:0000922//spindle pole GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003774//motor activity GO:0000278//mitotic cell cycle;GO:0009605//response to external stimulus;GO:0009639//response to red or far red light;GO:0051297//centrosome organization;GO:0050658//RNA transport;GO:0007051//spindle organization;GO:0045165//cell fate commitment;GO:0051276//chromosome organization;GO:0015031//protein transport;GO:0009648//photoperiodism;GO:0007292//female gamete generation;GO:0030859//polarized epithelial cell differentiation;GO:0008088//axon cargo transport;GO:0035270//endocrine system development;GO:0042051//compound eye photoreceptor development 34978 1445.00 17.55 30.345 0.789987790087516 Up 0.654570070003963 Idgf1 imaginal disc growth factor 1 K01183|1|3e-35|149|dme:Dmel_CG9357|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0070851//growth factor receptor binding;GO:0043167//ion binding GO:0048513//organ development;GO:0006026 32135 3994.54 23.34 24.34 0.0605246070063803 Up 0.149914146083741 CG1578 CG1578, isoform C K13761|1|1e-09|66.2|smm:Smp_163100|high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] - - - 3771961 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 19836085 333.00 1.195 0.795 -0.587983852696393 Down 0.196341302337868 19835420 603.00 0.28 0.23 -0.283792966000591 Down 0.0694426099590543 43901 5721.11 18.77 19.965 0.0890444218021737 Up 0.188812574296658 chb chromosome bows, isoform C - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0045171//intercellular bridge;GO:0000922//spindle pole;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0045171//intercellular bridge;GO:0000922//spindle pole;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0045171//intercellular bridge;GO:0000922//spindle pole GO:0032561//guanyl ribonucleotide binding;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0015631//tubulin binding GO:0000819//sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007088//regulation of mitosis;GO:0007308//oocyte construction;GO:0006935//chemotaxis;GO:0007293//germarium-derived egg chamber formation;GO:0000819//sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007088//regulation of mitosis;GO:0007308//oocyte construction;GO:0006935//chemotaxis;GO:0007293//germarium-derived egg chamber formation;GO:0000819//sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007088//regulation of mitosis;GO:0007308//oocyte construction;GO:0006935//chemotaxis;GO:0007293//germarium-derived egg chamber formation 32162 4237.89 12.465 9.955 -0.324389661770998 Down 0.401267996301677 fw furrowed, isoform C K04012|1|2e-65|252|oaa:100084581|complement component (3d/Epstein Barr virus) receptor 2 - GO:0030246//carbohydrate binding;GO:0030246//carbohydrate binding GO:0009987//cellular process;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007472//wing disc morphogenesis 2768664 965.00 0.365 0.23 -0.666262602823004 Down 0.111279883767006 CG33325 CG33325 - - - - 35152 1309.56 64.78 41.755 -0.633599503042355 Down 0.654966318848237 CG10621 CG10621, isoform C K00547|1|0.0|640|dpo:Dpse_GA10443|homocysteine S-methyltransferase [EC:2.1.1.10] - GO:0008172 - 38842 1337.41 20.26 17.845 -0.183114272752115 Down 0.316668868049135 CG8539 CG8539, isoform B K01298|1|1e-39|164|mmu:232680|carboxypeptidase A2 [EC:3.4.17.15] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 35814 1910.00 18.045 13.395 -0.429904562054854 Down 0.505250297186633 CG2121 CG2121, isoform B - - - GO:0006810//transport;GO:0006810//transport 39062 1318.41 39.72 39.56 -0.00582319676926291 Down 0.0592722229560164 PGRP-LA peptidoglycan recognition protein LA, isoform G K01446|1|3e-132|472|dme:Dmel_CG32042|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0002376//immune system process;GO:0009581//detection of external stimulus;GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0002376//immune system process;GO:0009581//detection of external stimulus;GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0002376//immune system process;GO:0009581//detection of external stimulus;GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0002376//immune system process;GO:0009581//detection of external stimulus 35251 910.00 0.095 0.055 -0.788495894806288 Down 0.0694426099590543 CG13078 CG13078 K08371|1|9e-12|70.9|dpo:Dpse_GA10125|cytochrome b-561 domain containing 2 - - - 43029 802.00 16.945 9.98 -0.763747916146734 Down 0.608836349227315 CG13663 CG13663 - - - - 19835543 1132.58 6.33 6.095 -0.0545792788081293 Down 0.0889578655395588 34961 3130.00 7.485 6.86 -0.125793739885604 Down 0.173986263373398 heix heixuedian K02548|1|2e-156|553|dpo:Dpse_GA19197|1,4-dihydroxy-2-naphthoate octaprenyltransferase [EC:2.5.1.-] GO:0031224//intrinsic to membrane GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0009233 35743 1412.00 9.57 9.835 0.0394061277925047 Up 0.0896182802800159 Or43b odorant receptor 43b K08471|1|0.0|741|dme:Dmel_CG17853|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33369 1101.45 47.15 42.95 -0.134599639536633 Down 0.292332584863294 Der-1 Derlin-1, isoform B K11519|1|2e-144|511|dme:Dmel_CG10908|Derlin-1 - - - 31025 1603.00 70.645 88.04 0.317571689843226 Up 0.53232730154537 CG13360 CG13360 - - - - 36125 12900.33 4.87 6.075 0.318962636410801 Up 0.305705983357549 stan starry night, isoform G K04600|1|0.0|6806|dme:Dmel_CG11895|cadherin EGF LAG seven-pass G-type receptor 1 (flamingo) GO:0016021//integral to membrane;GO:0030054//cell junction;GO:0016021//integral to membrane;GO:0030054//cell junction;GO:0016021//integral to membrane;GO:0030054//cell junction GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity GO:0048812//neuron projection morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0001752//compound eye photoreceptor fate commitment;GO:0016337//cell-cell adhesion;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0035151//regulation of tube size, open tracheal system;GO:0001736//establishment of planar polarity;GO:0044087;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0023060;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042051//compound eye photoreceptor development;GO:0048812//neuron projection morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0001752//compound eye photoreceptor fate commitment;GO:0016337//cell-cell adhesion;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0035151//regulation of tube size, open tracheal system;GO:0001736//establishment of planar polarity;GO:0044087;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0023060;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042051//compound eye photoreceptor development;GO:0048812//neuron projection morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0001752//compound eye photoreceptor fate commitment;GO:0016337//cell-cell adhesion;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0035151//regulation of tube size, open tracheal system;GO:0001736//establishment of planar polarity;GO:0044087;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0023060;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042051//compound eye photoreceptor development 42025 3849.37 550.63 653.2 0.246441576403531 Up 0.486593580768723 Fas1 fasciclin 1, isoform G - GO:0016020//membrane;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0006935//chemotaxis;GO:0016337//cell-cell adhesion;GO:0008037//cell recognition;GO:0006935//chemotaxis;GO:0016337//cell-cell adhesion;GO:0008037//cell recognition 41951 973.00 4.815 4.865 0.0149040069376523 Up 0.0492999603751156 CG5013 CG5013 - - - - 34321 4136.00 17.04 13.94 -0.289694774357415 Down 0.409853387927619 CG4619 CG4619, isoform B - GO:0043234//protein complex;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0032559 GO:0006909//phagocytosis;GO:0006909//phagocytosis 43688 4794.15 0.55 0.34 -0.69389687227432 Down 0.141526878879937 CG31004 mesh, isoform E K06826|1|1e-07|59.7|dwi:Dwil_GK17793|nidogen (entactin);K03900|3|6e-06|54.3|rno:116669|von Willebrand factor - - GO:0031589//cell-substrate adhesion;GO:0031589//cell-substrate adhesion;GO:0031589//cell-substrate adhesion;GO:0031589//cell-substrate adhesion 43392 11637.97 8.715 10.93 0.32672083154622 Up 0.387993660018492 htt huntingtin, isoform B K04533|1|0.0|6090|dme:Dmel_CG9995|huntingtin GO:0043231//intracellular membrane-bounded organelle GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization 19835362 300.00 11.215 9.205 -0.284939993736366 Down 0.355930524369304 37092 770.40 6.47 3.33 -0.958243534921245 Down 0.532228239334302 CG14502 CG14502, isoform D - - - - 43080 4496.20 24.065 25.235 0.0684896633335543 Up 0.165797120591732 XNP XNP, isoform D K10779|1|0.0|638|tgu:100229394|transcriptional regulator ATRX [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0032559 GO:0048731;GO:0010467//gene expression;GO:0043408//regulation of MAPK cascade;GO:0006996//organelle organization;GO:0012502//induction of programmed cell death;GO:0006935//chemotaxis;GO:0016477//cell migration;GO:0048731;GO:0010467//gene expression;GO:0043408//regulation of MAPK cascade;GO:0006996//organelle organization;GO:0012502//induction of programmed cell death;GO:0006935//chemotaxis;GO:0016477//cell migration 37776 1056.00 18.505 17.96 -0.0431277855590736 Down 0.11028926165632 eIF6 eIF6 K03264|1|4e-134|477|dme:Dmel_CG17611|translation initiation factor eIF-6 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0005882//intermediate filament GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0042255//ribosome assembly 19835139 2593.00 0.035 0.07 1 Up 0.0725795799762251 - CG45062, isoform B - - - - 37760 581.00 0.08 0.1 0.321928094887362 Up 0.0540219257693832 CG11300 CG11300 - - - - 39161 3157.40 50.335 58.225 0.21007682015151 Up 0.408334434024567 CG8108 CG8108, isoform B - - - - 31964 2856.00 69.64 67.235 -0.0507037619279699 Down 0.151135913353586 l(1)G0289 lethal (1) G0289 K07960|1|9e-54|212|ptr:454623|ADP-ribosylation factor-like 12 GO:0031224//intrinsic to membrane - - 14462911 636.00 0.07 0.48 2.77760757866355 Up 0.259542992999604 31226 1537.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG12496 CG12496 - - - - 319046 714.41 9.05 8.09 -0.16177808954059 Down 0.222989037115308 CG31957 CG31957, isoform B - - GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 41161 2217.00 35.96 28.445 -0.338217939819686 Down 0.509906221106855 P58IPK P58IPK K09523|1|0.0|920|dme:Dmel_CG8286|DnaJ homolog subfamily C member 3 - GO:0005515//protein binding - 38849 2586.00 0.81 0.66 -0.295455883526172 Down 0.106326773213578 CG14837 CG14837 - - - - 39085 1529.00 223.765 165.435 -0.435719907774696 Down 0.61781798969753 aay astray K01079|1|2e-140|499|dme:Dmel_CG3705|phosphoserine phosphatase [EC:3.1.3.3] GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0016791//phosphatase activity GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0006563//L-serine metabolic process 42963 708.00 5.575 5.1 -0.128474557948809 Down 0.155065381059305 CG7006 CG7006 K07565|1|5e-91|333|dpo:Dpse_GA20024|60S ribosome subunit biogenesis protein NIP7 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis 39650 4080.28 5.335 6.56 0.298207543793659 Up 0.301908598599921 CG12316 CG12316, isoform B - - - - 40262 1860.25 6.95 8.28 0.252617789888456 Up 0.292761854444591 CG5872 CG5872, isoform B - - - - 38419 387.00 101.28 138.09 0.447259538516701 Up 0.616266015057456 Drs drosomycin - - - GO:0050832//defense response to fungus;GO:0042742//defense response to bacterium 19834896 1219.00 13.48 13.065 -0.0451133718618375 Down 0.109166556597543 41021 410.00 9.79 14.005 0.516561218470811 Up 0.517401928411042 CG8021 CG8021 K13044|1|4e-11|66.2|oaa:100073407|heterogeneous nuclear ribonucleoprotein A/B/D - GO:0005488//binding - 40299 1045.82 45.25 39.73 -0.187688998769831 Down 0.374224012679963 CG4365 CG4365, isoform C K01069|1|2e-158|558|dme:Dmel_CG4365|hydroxyacylglutathione hydrolase [EC:3.1.2.6] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding GO:0019852//L-ascorbic acid metabolic process 32037 869.00 20.945 15.085 -0.473491187719821 Down 0.540648527275129 CG1537 CG1537 - - - - 44029 1328.00 49.575 39.775 -0.3177508418978 Down 0.512448817857615 Ref1 RNA and export factor binding protein 1 K12881|1|6e-111|400|dme:Dmel_CG1101|THO complex subunit 4 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005635//nuclear envelope GO:0003723//RNA binding GO:0051276//chromosome organization;GO:0000377;GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0006351//transcription, DNA-dependent;GO:0007140//male meiosis 33852 1556.29 243.66 270.73 0.151985330530468 Up 0.352793554352133 CG9140 CG9140, isoform B K03942|1|0.0|900|dme:Dmel_CG9140|NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0000166//nucleotide binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain;GO:0051234//establishment of localization 34437 3499.00 62.165 74.98 0.270403279648997 Up 0.479890371153084 LM408 lysosomal alpha-mannosidase, isoform B K12311|1|0.0|2164|dme:Dmel_CG6206|lysosomal alpha-mannosidase [EC:3.2.1.24] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0016866//intramolecular transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0015923//mannosidase activity;GO:0016866//intramolecular transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0015923//mannosidase activity GO:0009451//RNA modification;GO:0019318//hexose metabolic process;GO:0009451//RNA modification;GO:0019318//hexose metabolic process 19835866 673.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 41499 1115.00 51.405 17.015 -1.59510154127532 Down 0.752575617487782 CG4115 CG4115 - - - - 14462456 1383.00 0.11 0.125 0.184424571137428 Up 0.0511161009113723 44505 5323.94 4.665 5.285 0.180026390530924 Up 0.190265486725664 br broad, isoform Q K02174|1|0.0|697|dme:Dmel_CG11491|broad;K09237|3|6e-35|150|aga:AgaP_AGAP003537|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051707//response to other organism;GO:0055002//striated muscle cell development;GO:0035071//salivary gland cell autophagic cell death;GO:0007292//female gamete generation;GO:0035112//genitalia morphogenesis;GO:0044248//cellular catabolic process;GO:0050793//regulation of developmental process 39844 894.90 10.695 10.335 -0.0493980937395967 Down 0.104411570466253 Smn survival motor neuron, isoform B K13129|1|2e-55|215|dan:Dana_GF10520|survival motor neuron protein GO:0031674//I band;GO:0016604//nuclear body;GO:0030529//ribonucleoprotein complex;GO:0045202//synapse GO:0042805//actinin binding GO:0048741//skeletal muscle fiber development;GO:0022613//ribonucleoprotein complex biogenesis;GO:0000398//mRNA splicing, via spliceosome;GO:0007015//actin filament organization 19835882 988.00 0.315 0.315 0 - 0.0382380134724607 48613 1230.65 7.75 7.565 -0.0348562279448628 Down 0.0753203011491217 CG5704 CG5704, isoform B K01175|1|1e-24|114|mmu:68607| [EC:3.1.-.-];K13700|2|2e-06|53.5|mdo:100014368|abhydrolase domain-containing protein 6 [EC:3.1.1.23];K13703|3|6e-06|52.0|nvi:100122014|abhydrolase domain-containing protein 11 - - - 3771851 549.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG33927 CG33927 K12602|1|1e-27|122|dpo:Dpse_GA17766|WD repeat-containing protein 61;K09255|2|3e-08|57.8|dpe:Dper_GL18753|Rel/ankyrin family, other - - - 35673 1484.00 15.59 15.95 0.0329354959544471 Up 0.0906419231277242 CG11127 CG11127 - - - - 7354384 1247.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 3885668 1026.00 0.235 1.51 2.68381588764744 Up 0.443996830009246 CG33965 CG33965 K10693|1|2e-12|72.8|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0044464//cell part - GO:0051234//establishment of localization 3346224 1566.00 0.25 1.05 2.0703893278914 Up 0.348104609694888 CG33510 CG33510 - - - - 32381 2100.82 209.485 158.585 -0.401590626617321 Down 0.59684982168802 CG1461 CG1461, isoform B K00815|1|0.0|956|dme:Dmel_CG1461|tyrosine aminotransferase [EC:2.6.1.5] - GO:0070547;GO:0048037//cofactor binding;GO:0016846//carbon-sulfur lyase activity GO:0006520//cellular amino acid metabolic process 36193 1386.00 40.16 30.515 -0.396240678877381 Down 0.552139743759081 Cpr47Ee cuticular protein 47Ee - - GO:0005198//structural molecule activity - 5740833 150.00 0.01 0.5 5.64385618977472 Up 0.36075155197464 48772 852.00 0.19 0.505 1.41028396930821 Up 0.204761590278695 nimC3 nimrod C3 - - GO:0015645//fatty acid ligase activity GO:0006631//fatty acid metabolic process 19835752 585.54 17.795 18.455 0.0525398047358229 Up 0.124917448157443 35035 3625.72 5.645 5.92 0.0686235948559491 Up 0.101868973715493 beat-IIIa beat-IIIa, isoform E - - - - 36197 548.00 21.16 26.105 0.302986531233902 Up 0.457733456610752 CG9067 CG9067 - GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle - GO:0048193//Golgi vesicle transport 37201 4098.86 16.095 15.51 -0.0534138904415873 Down 0.120756835292564 ena enabled, isoform G K05746|1|5e-41|170|mdo:100025688|enabled - - - 34222 1407.10 11.355 11.14 -0.0275784733668561 Down 0.0771364416853784 rost rolling stone, isoform C - GO:0031224//intrinsic to membrane - GO:0014706//striated muscle tissue development;GO:0000768//syncytium formation by plasma membrane fusion 34807 514.00 0.87 0.895 0.0408722814155282 Up 0.0480451723682473 Acyp acylphosphatase, isoform B K01512|1|6e-68|255|dme:Dmel_CG16870|acylphosphatase [EC:3.6.1.7] - GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides - 40231 1411.94 33.425 32.08 -0.0592534185257948 Down 0.158730682868842 CG6597 CG6597, isoform E - - - - 39648 2069.82 20.525 15.175 -0.435685705522123 Down 0.524072117289658 CG16959 CG16959, isoform E - - - - 33744 622.94 176.6 162.025 -0.124268908929985 Down 0.297781006472064 CG8680 CG8680, isoform C K03939|1|1e-73|275|dme:Dmel_CG8680|NADH dehydrogenase (ubiquinone) Fe-S protein 6 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain - - 5740108 806.00 0.295 0.5 0.761213140412884 Up 0.141725003302074 CG34188 CG34188 - - - - 40449 1456.00 12.89 13.14 0.0277130119606787 Up 0.081197992339189 CG7133 CG7133 K09519|1|2e-12|73.9|cin:445757|DnaJ homolog subfamily B member 13;K09515|2|3e-12|73.6|smm:Smp_078800|DnaJ homolog subfamily B member 9;K09502|4|4e-12|72.8|cbr:CBG19766|DnaJ homolog subfamily A member 1 GO:0044424//intracellular part GO:0043169//cation binding;GO:0005515//protein binding GO:0009790//embryo development;GO:0000278//mitotic cell cycle;GO:0010259//multicellular organismal aging;GO:0006950//response to stress;GO:0044267//cellular protein metabolic process 19835215 451.00 2.18 2.025 -0.106406227004939 Down 0.0853586052040682 31824 1074.00 8.835 9.245 0.065443184852579 Up 0.11943600581165 CG10962 CG10962 K11539|1|5e-15|82.0|mdo:100015144|carbonyl reductase 4 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 36656 2074.00 19.115 20.005 0.0656554285109531 Up 0.1547681944261 HPS1 Hermansky-Pudlak syndrome 1 ortholog - - - - 12798061 667.00 0.125 0.27 1.11103131238874 Up 0.13102628450667 31550 12622.47 31.24 43.42 0.474965272473165 Up 0.589882446176199 Ca-alpha1T Ca[2+]-channel protein alpha[[1]] subunit T, isoform F K05315|1|0.0|4023|dme:Dmel_CG15899|voltage-dependent calcium channel alpha 1, invertebrate - - - 43771 1008.32 93.435 93.3 -0.00208599206845543 Down 0.0457337207766477 CG2219 ADP ribosylation factor-like 4, isoform C K07977|1|3e-166|584|dme:Dmel_CG2219|Arf/Sar family, other;K07945|3|9e-52|203|gga:420589|ADP-ribosylation factor-like 4A - - - 31043 1515.00 12.25 11.895 -0.0424264774647983 Down 0.0987650244353454 CG3704 CG3704 K06883|1|0.0|696|dme:Dmel_CG3704| - - - 43750 2920.00 13.81 10.52 -0.392578614965749 Down 0.456478668603883 CG2118 CG2118, isoform D K01968|1|0.0|1366|dme:Dmel_CG2118|3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4] GO:0031980;GO:0031980 GO:0019842//vitamin binding;GO:0003824//catalytic activity;GO:0032559;GO:0019842//vitamin binding;GO:0003824//catalytic activity;GO:0032559 GO:0009081//branched-chain amino acid metabolic process;GO:0009081//branched-chain amino acid metabolic process 40222 951.95 7.38 6.83 -0.111735237770306 Down 0.155692775062739 CG6951 CG6951, isoform B K01493|1|9e-115|413|dme:Dmel_CG6951|dCMP deaminase [EC:3.5.4.12] - GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding - 8674071 691.00 44.785 48.82 0.12445668893577 Up 0.275624091929732 CG42497 CG42497 - GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 50224 379.00 10.49 12.8 0.287129132310095 Up 0.377327961960111 CG13018 CG13018 - - - - 40596 10175.76 24.825 28.285 0.188243453228038 Up 0.349887729494122 ctrip circadian trip, isoform M K10590|1|0.0|3197|dse:Dsec_GM10679|E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 38473 1937.90 116.13 77.29 -0.587387042114176 Down 0.659556201294413 CG11594 CG11594, isoform E K00875|1|4e-56|219|mcc:693720|D-ribulokinase [EC:2.7.1.47] - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 19835834 627.00 0.325 0.22 -0.562936194391157 Down 0.101241579712059 33802 1967.37 0.535 0.55 0.0398927271235128 Up 0.0449742438251222 CG14006 CG14006, isoform B - - - GO:0043101//purine-containing compound salvage 39041 1588.93 1510.96 1596.225 0.0791985564812363 Up 0.226456214502708 Argk arginine kinase, isoform H K00934|1|0.0|727|dme:Dmel_CG32031|arginine kinase [EC:2.7.3.3];K00933|2|0.0|723|dya:Dyak_GE21263|creatine kinase [EC:2.7.3.2] - GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559;GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559;GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559;GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559;GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559;GO:0016775//phosphotransferase activity, nitrogenous group as acceptor;GO:0032559 GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 31189 1932.10 56.645 34.385 -0.720169270760644 Down 0.670684189671113 CG3630 CG3630, isoform D - - - - 12798136 883.20 6.08 6.33 0.0581341759847559 Up 0.0939439968300092 31494 1676.00 0.26 0.25 -0.0565835283663676 Down 0.0422335226522256 CG15773 CG15773, isoform B - - - - 33371 813.00 6.13 4.94 -0.311376032106104 Down 0.300191520274733 CG15362 CG15362 K10863|1|1e-12|72.4|tca:658572|aprataxin [EC:3.-.-.-] - - - 43424 1519.00 0.175 0.15 -0.222392421336448 Down 0.0521727644961036 Ssl2 strictosidine synthase-like 2 K01757|1|0.0|777|dme:Dmel_CG11833|strictosidine synthase [EC:4.3.3.2];K01774|2|2e-129|462|dme:Dmel_CG3373| [EC:4.-.-.-] GO:0044444//cytoplasmic part GO:0016843;GO:0003723//RNA binding;GO:0004871//signal transducer activity;GO:0004175//endopeptidase activity GO:0008152//metabolic process 31211 3979.73 20.425 22.42 0.134450199772381 Up 0.259774138158764 CG3078 CG3078, isoform B - - - - 42968 1286.00 34.145 27.46 -0.314342708423358 Down 0.484216087703078 CG7016 CG7016 - - - - 35065 1412.00 0.65 0.99 0.606988807051155 Up 0.180755514463083 CG7094 CG7094 K02218|1|1e-108|393|dpo:Dpse_GA15193|casein kinase 1 [EC:2.7.11.1];K08957|2|7e-108|390|dre:192307|casein kinase 1, alpha [EC:2.7.11.1] GO:0044424//intracellular part GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 42869 1373.00 10.385 10.065 -0.0451540439233079 Down 0.0997556465460309 CG6182 CG6182 - GO:0000314//organellar small ribosomal subunit;GO:0000315//organellar large ribosomal subunit GO:0005099//Ras GTPase activator activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0032318//regulation of Ras GTPase activity 39439 2918.00 2.275 2.715 0.255085652718303 Up 0.17365605600317 ara araucan, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007472//wing disc morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048592//eye morphogenesis;GO:0001708//cell fate specification;GO:0048859//formation of anatomical boundary;GO:0007472//wing disc morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048592//eye morphogenesis;GO:0001708//cell fate specification;GO:0048859//formation of anatomical boundary 12798516 476.00 65.265 68.72 0.0744205188767779 Up 0.191091005151235 CG43093 CG43093 - - - - 32131 1384.73 9.92 9.185 -0.111060399275526 Down 0.175009906221107 Karl karl, isoform D - - - - 39713 1692.00 0.16 0.3 0.906890595608518 Up 0.122011623299432 CG7304 CG7304 K00710|1|0.0|1097|dme:Dmel_CG7304|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process 326181 1764.69 0.055 0.055 3.20342650381492e-16 Up 0.0382380134724607 CG31976 CG31976, isoform C - - - - 35797 739.00 89.355 63.515 -0.49245111405862 Down 0.623299432043323 CG14757 CG14757 - GO:0043231//intracellular membrane-bounded organelle - GO:0018065//protein-cofactor linkage;GO:0022904//respiratory electron transport chain 36593 2984.00 61.01 60.425 -0.0139001626846858 Down 0.0672302205785233 CG8613 CG8613 - - GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses - 42148 7066.43 12.85 15.19 0.241353510420843 Up 0.351968035926562 tinc tincar, isoform G K13280|1|9e-64|246|aga:AgaP_AGAP001696|signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-] - - - 3885575 425.00 23.85 19.77 -0.270676395163666 Down 0.420849293356228 CG33977 CG33977 K09659|1|2e-44|176|dme:Dmel_CG33977|dolichyl-phosphate mannosyltransferase polypeptide 3 - - - 10178940 351.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 CG42718 CG42718 - - - - 40156 2055.00 3.24 3.65 0.171902650882755 Up 0.153447364945186 CG14102 CG14102 - - - - 34372 912.00 26.59 28.99 0.124671556203729 Up 0.257231541408004 Mob3 Mob3 K06685|1|2e-85|315|xtr:496492|maintenance of ploidy protein MOB1 (MPS1 binder 1) - GO:0005488//binding - 19835472 534.00 1.355 0.11 -3.62271742271657 Down 0.464766873596619 32901 1814.00 0.21 0.29 0.465663572348812 Up 0.088264430062079 Inx5 innexin 5 - GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane GO:0022829//wide pore channel activity - 43351 4587.93 4.915 4.235 -0.214829447008382 Down 0.206313564918769 Mes-4 Mes-4, isoform B K11424|1|0.0|2679|dme:Dmel_CG4976|histone-lysine N-methyltransferase NSD1/2 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005515//protein binding GO:0007275//multicellular organismal development;GO:0009987//cellular process 35902 6171.00 0.775 0.155 -2.32192809488736 Down 0.314918768986924 CG8213 CG8213, isoform D K01312|1|1e-59|233|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K08670|2|1e-42|176|xla:394363|suppressor of tumorigenicity protein 14 [EC:3.4.21.109];K09640|3|2e-42|176|dre:562051|transmembrane protease, serine 9 [EC:3.4.21.-];K09641|5|5e-42|174|bta:521615|transmembrane protease, serine 11D [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 36732 3395.00 9.36 9.42 0.00921853002937863 Up 0.0502575617487782 Ranbp11 Ranbp11 - - GO:0022892 GO:0015031//protein transport 37787 1397.00 21.96 23.145 0.0758225082866924 Up 0.177387399286752 CG4882 CG4882, isoform B - - GO:0001071//nucleic acid binding transcription factor activity - 12798543 311.00 0.91 1.44 0.662130361243616 Up 0.231244221371021 53511 1936.51 36.555 45.55 0.317382302244916 Up 0.508156122044644 Ugt36Bc Ugt36Bc, isoform C K00699|1|0.0|1018|dme:Dmel_CG17932|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups - 33516 1488.69 35.695 39.805 0.157227660506501 Up 0.328325188218201 GABPI beta4GalNAcTB pilot, isoform D - - GO:0046914//transition metal ion binding - 31921 666.00 546.965 398.935 -0.455294816887599 Down 0.633403777572315 CG9686 CG9686 - - - - 38360 2194.85 46.93 53.435 0.187274558436017 Up 0.380729097873465 CG2162 CG2162, isoform F - - GO:0005488//binding;GO:0005488//binding - 35680 6377.11 19.13 26.27 0.457579326787519 Up 0.555408796724343 didum dilute class unconventional myosin, isoform C K10357|1|0.0|2288|dme:Dmel_CG2146|myosin V GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0017022//myosin binding;GO:0003779//actin binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0017022//myosin binding;GO:0003779//actin binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0017022//myosin binding;GO:0003779//actin binding;GO:0032559;GO:0042623//ATPase activity, coupled GO:0007317//regulation of pole plasm oskar mRNA localization;GO:0042051//compound eye photoreceptor development;GO:0007317//regulation of pole plasm oskar mRNA localization;GO:0042051//compound eye photoreceptor development;GO:0007317//regulation of pole plasm oskar mRNA localization;GO:0042051//compound eye photoreceptor development 33288 2064.01 132.975 118.27 -0.169070866407745 Down 0.37627129837538 Pino pinocchio, isoform C - - - GO:0007635//chemosensory behavior;GO:0007635//chemosensory behavior 19836124 1427.00 2.99 1.505 -0.990381997438403 Down 0.409655263505481 5740655 2145.00 0.675 1.285 0.928808952143047 Up 0.268788799366002 CG34431 CG34431 - - - - 43378 1425.00 0.03 0.035 0.222392421336448 Up 0.0461960110949676 CG1894 CG1894 K11308|1|0.0|823|dme:Dmel_CG1894|histone acetyltransferase MYST1 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0000805//X chromosome GO:0010485//H4 histone acetyltransferase activity;GO:0003723//RNA binding GO:0006473//protein acetylation;GO:0016570//histone modification;GO:0007549//dosage compensation 19835759 588.00 0.495 0.935 0.917537839808027 Up 0.226291110817593 19835453 371.00 0.235 0.44 0.90484276695966 Up 0.146149782063136 33995 4467.49 35.23 37.58 0.0931605919250917 Up 0.214964998018756 Pvf3 PDGF- and VEGF-related factor 3, isoform F K05448|1|7e-06|52.8|oaa:100077009|vascular endothelial growth factor A/B, PGF GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0007431//salivary gland development;GO:0016477//cell migration;GO:0007431//salivary gland development;GO:0016477//cell migration;GO:0007431//salivary gland development;GO:0016477//cell migration 14462893 610.00 1.225 2.02 0.721573543749224 Up 0.292530709285431 3355041 1555.55 138.41 144.53 0.0624208029197892 Up 0.178311979923392 eIF-4B eukaryotic initiation factor 4B, isoform F K03258|1|0.0|703|dme:Dmel_CG10837|translation initiation factor eIF-4B GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0006412//translation;GO:0006412//translation 37867 1471.66 232.475 273.83 0.236204933249625 Up 0.471205917316074 Dat dopamine N acetyltransferase, isoform B K00669|1|2e-138|492|dme:Dmel_CG3318|arylalkylamine N-acetyltransferase [EC:2.3.1.87] GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0008144//drug binding;GO:0008504//monoamine transmembrane transporter activity;GO:0008080//N-acetyltransferase activity;GO:0008144//drug binding;GO:0008504//monoamine transmembrane transporter activity;GO:0008080//N-acetyltransferase activity GO:0051937;GO:0042428//serotonin metabolic process;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042417//dopamine metabolic process;GO:0019336;GO:0032502//developmental process;GO:0051937;GO:0042428//serotonin metabolic process;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042417//dopamine metabolic process;GO:0019336;GO:0032502//developmental process 30998 3313.67 122.345 127.62 0.060899296624784 Up 0.177387399286752 svr silver, isoform N K07752|1|0.0|2539|dse:Dsec_GM19071|carboxypeptidase D [EC:3.4.17.22] - - - 38533 1155.00 6.795 6.175 -0.138034414295351 Down 0.177882710342095 CG15014 CG15014 K06963|1|8e-120|430|dme:Dmel_CG15014| - - - 53523 1105.00 4.875 2.485 -0.972156367074687 Down 0.489004094571391 lectin-46Ca lectin-46Ca - - GO:0030246//carbohydrate binding GO:0045297//post-mating behavior;GO:0048609//multicellular organismal reproductive process 32504 1554.77 60.395 42.27 -0.514795003840723 Down 0.618214238541804 CG8128 CG8128, isoform B - - GO:0003824//catalytic activity - 36285 1758.36 135.665 167.605 0.305016618088266 Up 0.53533218861445 Mppe metallophosphoesterase, isoform E - - GO:0003824//catalytic activity;GO:0003824//catalytic activity - 39659 3072.35 21.18 20.185 -0.0694190025118263 Down 0.15929203539823 Tak1 TGF-beta activated kinase 1, isoform B K04427|1|0.0|1122|dme:Dmel_CG18492|mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] - GO:0032559;GO:0004709//MAP kinase kinase kinase activity GO:0000186//activation of MAPKK activity;GO:0012501//programmed cell death;GO:0007389//pattern specification process;GO:0009886//post-embryonic morphogenesis;GO:0002252;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0002780 31074 980.00 0.45 0.83 0.88318633501725 Up 0.20783251882182 CG32812 CG32812, isoform B K06268|1|8e-119|427|dme:Dmel_CG32812|protein phosphatase 3, regulatory subunit - - - 19835257 327.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 43432 1113.43 2.04 1.16 -0.814444346843923 Down 0.312277110025096 CG11843 CG11843, isoform B K01312|1|2e-30|133|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01321|3|7e-26|117|dre:678552|coagulation factor IX (Christmas factor) [EC:3.4.21.22];K01315|4|1e-24|113|mdo:100028030|plasminogen [EC:3.4.21.7] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 5740723 420.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG34303 CG34303 K12602|1|5e-12|69.3|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 36238 10114.64 12.525 13.87 0.147157184241032 Up 0.248315942411835 E(Pc) enhancer of polycomb, isoform E K11322|1|0.0|2704|dme:Dmel_CG7776|enhancer of polycomb-like protein GO:0005720//nuclear heterochromatin;GO:0005700//polytene chromosome;GO:0005720//nuclear heterochromatin;GO:0005700//polytene chromosome - - 19836162 4754.00 0.58 0.95 0.711874613203376 Up 0.194492141064589 35952 1195.00 17.095 16.63 -0.0397862541461255 Down 0.105831462158235 CG2063 CG2063 - GO:0005681//spliceosomal complex - GO:0000377 40949 2649.00 4.315 4.905 0.184892577040284 Up 0.185279355435213 Pbp95 PSEA-binding protein 95kD K09453|1|1e-27|125|tgu:100222127|snRNA-activating protein complex subunit 4 GO:0005667//transcription factor complex GO:0043566//structure-specific DNA binding GO:0006383//transcription from RNA polymerase III promoter;GO:0010468//regulation of gene expression;GO:0034622 42702 2208.00 22.36 20.93 -0.095347876587481 Down 0.208228767666094 CG7023 Ubiquitin-specific protease 12/46 ortholog K11842|1|0.0|715|dse:Dsec_GM26467|ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process 12798427 2060.00 3.835 3.185 -0.267933205246633 Down 0.214502707700436 36382 7731.38 26.82 29.74 0.149095410147945 Up 0.301908598599921 Sin3A Sin3A, isoform I K11644|1|0.0|2881|dme:Dmel_CG8815|paired amphipathic helix protein Sin3a GO:0070822//Sin3-type complex;GO:0070822//Sin3-type complex;GO:0070822//Sin3-type complex;GO:0070822//Sin3-type complex;GO:0070822//Sin3-type complex;GO:0070822//Sin3-type complex GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 33823 3302.48 0.32 0.59 0.882643049361841 Up 0.171740853255845 dsf dissatisfaction, isoform B K07295|1|4e-154|545|dme:Dmel_CG9019|nuclear receptor subfamily 2 group A GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0060180//female mating behavior;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007275//multicellular organismal development;GO:0003006//developmental process involved in reproduction;GO:0007619//courtship behavior 32062 559.00 1.955 2.835 0.536180127634877 Up 0.290021133271695 CG11106 CG11106, isoform B - - - - 43620 2248.00 33.055 31.975 -0.0479241555794833 Down 0.138521991810857 PH4alphaEFB prolyl-4-hydroxylase-alpha EFB K00472|1|0.0|1056|dme:Dmel_CG31022|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0019471 35895 4523.00 0.655 0.645 -0.0221957461141962 Down 0.0413749834896315 FANCI fanconi anemia complementation group I homologue K10895|1|0.0|2689|dme:Dmel_CG13745|fanconi anemia group I protein - - - 43844 3046.40 27.88 27.11 -0.0404054480307115 Down 0.118016114119667 Sox102F Sox102F, isoform D K09269|1|1e-48|194|xtr:100144640|transcription factor SOX5/6/13 (SOX group D) - - - 42047 1979.00 33.665 23.08 -0.544606240845408 Down 0.602859595826179 CG3534 CG3534 K00854|1|0.0|1079|dme:Dmel_CG3534|xylulokinase [EC:2.7.1.17] - - - 41776 5602.03 23.315 25.075 0.104991271159649 Up 0.218465196143178 l(3)L1231 lethal (3) L1231, isoform D K11668|1|7e-14|80.5|ame:725795|INO80 complex subunit D - - - 37893 5788.53 36.05 43.015 0.254840578302081 Up 0.43917580240391 slik Sterile20-like kinase, isoform G K08836|1|0.0|2093|dpo:Dpse_GA18234|STE20-like kinase [EC:2.7.11.1];K12838|3|5e-146|520|tca:663345|poly(U)-binding-splicing factor PUF60 - GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0051301//cell division;GO:0001934//positive regulation of protein phosphorylation;GO:0051301//cell division;GO:0001934//positive regulation of protein phosphorylation;GO:0051301//cell division;GO:0001934//positive regulation of protein phosphorylation;GO:0051301//cell division;GO:0001934//positive regulation of protein phosphorylation;GO:0051301//cell division;GO:0001934//positive regulation of protein phosphorylation;GO:0051301//cell division;GO:0001934//positive regulation of protein phosphorylation 40229 4504.00 18.305 19.185 0.0677409912982478 Up 0.154107779685643 Pex23 peroxin 23 K06832|1|2e-11|72.8|tgu:100227037|galectin-8;K06831|2|5e-11|71.2|dre:327284|galectin-3 GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding - 31815 4092.88 20.485 17.56 -0.222275047944943 Down 0.361279883767006 CG12075 CG12075, isoform E - - - - 43078 1280.00 4.375 4.995 0.191201661072727 Up 0.192874124950469 CG4553 CG4553 - - - - 39125 901.00 47.965 30.945 -0.632275735038764 Down 0.643343019416193 CG18180 CG18180 K01310|1|7e-126|449|dme:Dmel_CG18179|chymotrypsin [EC:3.4.21.1];K01362|3|1e-57|223|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42788 712.00 48.67 46.25 -0.0735794089874655 Down 0.185081231013076 CG10157 CG10157 K08059|1|1e-15|82.8|oaa:100080212|interferon, gamma-inducible protein 30 - - - 43308 3015.00 0.61 0.605 -0.0118741002882918 Down 0.041044776119403 CG12885 CG12885, isoform B - - - - 246467 2533.00 1.17 1.61 0.460552158531212 Up 0.198718795403513 CG30120 CG30120 K10599|1|2e-20|101|dya:Dyak_GE13910|pre-mRNA-processing factor 19 [EC:6.3.2.19] - - - 19836169 448.00 1.72 2.92 0.763559804177919 Up 0.359001452912429 19835235 690.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 41890 551.00 39.39 55.84 0.503469524595609 Up 0.611709153348303 Trissin trissin, isoform C - - - - 5740619 506.00 297.005 295.63 -0.00669453960942464 Down 0.0694095892220314 31795 6308.58 11.325 11.555 0.0290062095340335 Up 0.0789195614846123 Trf4-1 Trf4-1, isoform J K03514|1|0.0|774|dme:Dmel_CG11265|DNA polymerase sigma subunit [EC:2.7.7.7] - GO:0070566//adenylyltransferase activity;GO:0034061;GO:0070566//adenylyltransferase activity;GO:0034061;GO:0070566//adenylyltransferase activity;GO:0034061;GO:0070566//adenylyltransferase activity;GO:0034061 GO:0007059//chromosome segregation;GO:0043629//ncRNA polyadenylation;GO:0007059//chromosome segregation;GO:0043629//ncRNA polyadenylation;GO:0007059//chromosome segregation;GO:0043629//ncRNA polyadenylation;GO:0007059//chromosome segregation;GO:0043629//ncRNA polyadenylation 3772417 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 39690 1059.45 27.86 26.85 -0.0532731697284779 Down 0.1367058512746 CG12304 CG12304, isoform B - - - - 59261 2141.00 12.79 12.035 -0.08778012240714 Down 0.164212125214635 CG3267 CG3267 K01969|1|0.0|1113|dme:Dmel_CG3267|3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4] GO:0031980 GO:0016421//CoA carboxylase activity GO:0006631//fatty acid metabolic process;GO:0006549//isoleucine metabolic process;GO:0006566//threonine metabolic process;GO:0006573//valine metabolic process;GO:0000098//sulfur amino acid catabolic process 33323 942.00 1.32 2.065 0.645603852060992 Up 0.276977942147669 CG5565 CG5565 - - GO:0016791//phosphatase activity - 32659 1818.00 0.185 0.335 0.856635824828823 Up 0.124719323735306 CG32568 CG32568, isoform C K11584|1|0.0|661|dme:Dmel_CG32568|protein phosphatase 2 (formerly 2A), regulatory subunit B' GO:0008287//protein serine/threonine phosphatase complex GO:0019888//protein phosphatase regulator activity GO:0007051//spindle organization;GO:0023060 47718 2253.74 6.135 5.815 -0.0772841521896867 Down 0.11121384229296 CG17829 CG17829, isoform C K09228|1|6e-21|102|rno:286979|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0031981//nuclear lumen;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0010556;GO:0048519//negative regulation of biological process;GO:0010468//regulation of gene expression;GO:0010604;GO:0006350;GO:0022402//cell cycle process;GO:0050794//regulation of cellular process 39763 2078.00 4.67 4.855 0.0560487457095305 Up 0.0850614185708625 IntS9 integrator 9 K13146|1|0.0|1334|dme:Dmel_CG5222|integrator complex subunit 9 GO:0005849//mRNA cleavage factor complex - GO:0006397//mRNA processing 40365 875.00 0.095 0.065 -0.547487795302493 Down 0.0619138819178444 CG12971 CG12971, isoform C - - - - 42076 3166.54 14.455 16.29 0.172417995048468 Up 0.287214370624752 m-cup mann-cup, isoform B K10349|1|7e-52|206|aag:AaeL_AAEL010108|Fem-1 homolog b - - - 43604 14807.00 3.15 3.655 0.214519577565159 Up 0.178675208030643 hdc headcase, isoform D - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0048675//axon extension;GO:0009996//negative regulation of cell fate specification;GO:0009266//response to temperature stimulus;GO:0043436;GO:0035194//posttranscriptional gene silencing by RNA;GO:0060446//branching involved in open tracheal system development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035146;GO:0048675//axon extension;GO:0009996//negative regulation of cell fate specification;GO:0009266//response to temperature stimulus;GO:0043436;GO:0035194//posttranscriptional gene silencing by RNA;GO:0060446//branching involved in open tracheal system development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035146;GO:0048675//axon extension;GO:0009996//negative regulation of cell fate specification;GO:0009266//response to temperature stimulus;GO:0043436;GO:0035194//posttranscriptional gene silencing by RNA;GO:0060446//branching involved in open tracheal system development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035146 36685 4286.05 11.78 12.22 0.052904745988269 Up 0.111742174085326 row relative of woc, isoform C K09229|1|8e-11|70.5|ptr:451633|KRAB and SCAN domains-containing zinc finger protein;K09228|2|1e-10|69.7|xla:397958|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0032991//macromolecular complex;GO:0044464//cell part;GO:0032991//macromolecular complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 36525 867.00 60.94 13.235 -2.20303130519109 Down 0.780709285431251 Cpr50Cb cuticular protein 50Cb - - - - 36379 711.00 6.735 7.24 0.104311751620902 Up 0.145324263637564 Ak6 adenylate kinase 6 K03133|1|2e-99|361|dse:Dsec_GM20351|transcription initiation factor TFIID subunit D7 - GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559 GO:0006464//cellular protein modification process 35086 1282.00 0.61 0.37 -0.721283971933937 Down 0.153645489367323 CG17681 CG17681 - - GO:0016407//acetyltransferase activity - 42521 3142.00 133.75 62.865 -1.08920996421146 Down 0.734876502443535 e ebony K00142|1|4e-25|117|hsa:132949|aminoadipate-semialdehyde dehydrogenase [EC:1.2.1.31];K01895|2|1e-15|85.9|tgu:100229569|acetyl-CoA synthetase [EC:6.2.1.1] GO:0044424//intracellular part GO:0005488//binding;GO:0022892;GO:0016874//ligase activity GO:0043041;GO:0048066//developmental pigmentation;GO:0006570//tyrosine metabolic process;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007564//regulation of chitin-based cuticle tanning;GO:0031327;GO:0006584//catecholamine metabolic process 38462 1075.00 3.11 6.965 1.16320877247065 Up 0.575485404834236 CG12766 CG12766 K00011|1|0.0|659|dme:Dmel_CG12766|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity GO:0008152//metabolic process 42752 6165.40 5.685 7.535 0.406447162705576 Up 0.382611279883767 orb oo18 RNA-binding protein, isoform G K02602|1|0.0|1124|dse:Dsec_GM23578|oo18 RNA-binding protein GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding GO:0008283//cell proliferation;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0019094//pole plasm mRNA localization;GO:0008283//cell proliferation;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0019094//pole plasm mRNA localization;GO:0008283//cell proliferation;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0019094//pole plasm mRNA localization;GO:0008283//cell proliferation;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0019094//pole plasm mRNA localization;GO:0008283//cell proliferation;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0019094//pole plasm mRNA localization;GO:0008283//cell proliferation;GO:0045727//positive regulation of translation;GO:0031124//mRNA 3'-end processing;GO:0019094//pole plasm mRNA localization 37825 2107.00 58.175 68.41 0.233807924391515 Up 0.437458724078721 CG3860 CG3860, isoform B - - - GO:0006810//transport;GO:0006629//lipid metabolic process 31521 1867.79 698.42 606.205 -0.204289121096413 Down 0.431019680359266 Act5C actin 5C, isoform E K05692|1|0.0|761|api:100145822|actin beta/gamma 1 - - - 36363 2156.00 70.275 50.585 -0.474301903484854 Down 0.608572183331132 Lac lachesin K06775|1|9e-28|125|mdo:100016404|neuronal growth regulator 1 GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane - GO:0010669//epithelial structure maintenance;GO:0060541//respiratory system development;GO:0035150//regulation of tube size;GO:0016337//cell-cell adhesion;GO:0002009//morphogenesis of an epithelium 53562 4131.83 11.81 11 -0.102505440985135 Down 0.175439175802404 tara taranis, isoform B - - - GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007450//dorsal/ventral pattern formation, imaginal disc 14462886 447.00 3.875 3.19 -0.28063988639673 Down 0.223022057852331 CG43885 CG43885 - - - - 42923 1201.00 0.505 0.715 0.501659854026595 Up 0.136111478008189 CG13622 CG13622 - - - - 38809 4021.27 3.245 4.095 0.33564497364187 Up 0.262779025227843 mus312 mutagen-sensitive 312, isoform E K10484|1|3e-11|71.6|dre:100001183|BTB/POZ domain-containing protein 12 GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0005488//binding;GO:0005488//binding GO:0007059//chromosome segregation;GO:0051276//chromosome organization;GO:0006310//DNA recombination;GO:0007059//chromosome segregation;GO:0051276//chromosome organization;GO:0006310//DNA recombination 39344 1912.70 0.765 1.035 0.436099114806673 Up 0.152060493990226 CG14128 CG14128, isoform F K12172|1|8e-09|62.4|dvi:Dvir_GJ24715|E3 SUMO-protein ligase RanBP2 - - - 44086 1358.00 49.86 50.17 0.00894205527279615 Up 0.0641923127724211 Dmn dynamitin K10424|1|0.0|705|dme:Dmel_CG8269|dynactin 2 GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity GO:0000226//microtubule cytoskeleton organization;GO:0051640//organelle localization;GO:0000087//M phase of mitotic cell cycle 46035 909.97 17.46 15.22 -0.198085200125895 Down 0.324990093778893 CCS copper chaperone for superoxide dismutase, isoform C K04569|1|1e-142|505|dme:Dmel_CG17753|copper chaperone for superoxide dismutase - GO:0016209//antioxidant activity;GO:0016531//copper chaperone activity;GO:0003824//catalytic activity;GO:0016209//antioxidant activity;GO:0016531//copper chaperone activity;GO:0003824//catalytic activity GO:0010259//multicellular organismal aging;GO:0006825//copper ion transport;GO:0006950//response to stress;GO:0031647//regulation of protein stability;GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0010259//multicellular organismal aging;GO:0006825//copper ion transport;GO:0006950//response to stress;GO:0031647//regulation of protein stability;GO:0006800//oxygen and reactive oxygen species metabolic process 36534 3274.00 0.17 0.12 -0.502500340529183 Down 0.0744287412495047 CG30484 CG30484 - - - - 43017 1420.00 6.575 6.065 -0.116483249059155 Down 0.154933298111214 Mocs2 molybdenum cofactor synthesis 2 - GO:0044444//cytoplasmic part GO:0003824//catalytic activity GO:0009108//coenzyme biosynthetic process 45880 1397.39 14.495 11.795 -0.297379914821934 Down 0.400805705983358 ImpL3 Ecdysone-inducible gene L3, isoform D K00016|1|2e-178|625|dme:Dmel_CG10160|L-lactate dehydrogenase [EC:1.1.1.27] GO:0044424//intracellular part GO:0004457//lactate dehydrogenase activity GO:0006007//glucose catabolic process 37253 2829.00 0.91 1.245 0.452207291869384 Up 0.170519085985999 CG16716 CG16716 K06047|1|1e-15|85.9|bta:514559|tubulin---tyrosine ligase [EC:6.3.2.25] - - - 14462672 868.85 0.135 0.755 2.48351723716161 Up 0.316041474045701 39173 2015.00 22.56 10.285 -1.13322527387386 Down 0.683066966054682 Nc Nedd2-like caspase K04489|1|0.0|924|dme:Dmel_CG8091|caspase invertebrate, apoptosis-related cysteine protease [EC:3.4.22.-] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0042802//identical protein binding GO:0051605;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0003006//developmental process involved in reproduction;GO:0010259//multicellular organismal aging;GO:0048102//autophagic cell death;GO:0001700//embryonic development via the syncytial blastoderm;GO:0012502//induction of programmed cell death;GO:0007399//nervous system development;GO:0042386//hemocyte differentiation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007435//salivary gland morphogenesis 41079 914.00 85.885 55.71 -0.624469867577901 Down 0.660513802668076 Prosbeta3 proteasome beta3 subunit K02735|1|1e-118|426|dya:Dyak_GE24806|20S proteasome subunit beta 3 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0006508//proteolysis 41253 3135.50 24.655 8.155 -1.59612347078923 Down 0.726059965658433 CG3999 CG3999, isoform B K00281|1|0.0|1925|dme:Dmel_CG3999|glycine dehydrogenase [EC:1.4.4.2] - GO:0048037//cofactor binding;GO:0016642 GO:0006546//glycine catabolic process 41653 1844.00 61.245 32.05 -0.934267711440204 Down 0.703704926693964 yellow-e yellow-e - - - - 36826 2121.09 189.8 192.155 0.017790524407834 Up 0.091566503764364 Vha44 vacuolar H[+] ATPase 44kD subunit, isoform F K02148|1|0.0|1247|dme:Dmel_CG8048|V-type H+-transporting ATPase subunit C [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006718//juvenile hormone biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006718//juvenile hormone biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006718//juvenile hormone biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006718//juvenile hormone biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006718//juvenile hormone biosynthetic process 34324 1602.00 5.14 4.62 -0.153875507777821 Down 0.167183991546691 CG4709 CG4709, isoform B K13103|1|1e-09|64.7|smm:Smp_139510|tuftelin-interacting protein 11 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0010468//regulation of gene expression 41522 1706.22 23.045 25.02 0.118628021829171 Up 0.247325320301149 CG5196 CG5196, isoform B - - - - 14462845 4558.43 8.34 12.905 0.629810852649306 Up 0.545337471932374 CG43783 CG43783, isoform G - - - - 36374 1910.00 2.805 3.29 0.230086813126449 Up 0.178708228767666 CG13151 CG13151 - - - - 34621 776.00 1502.785 1355.095 -0.149244624555856 Down 0.358869369964338 CG6770 CG6770 - - - - 3346239 1179.00 1.1 0.97 -0.181446871337532 Down 0.0903447364945186 CG33514 CG33514 K10693|1|1e-09|64.3|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0044464//cell part - GO:0051234//establishment of localization 12798068 539.00 0.39 0.105 -1.89308479608349 Down 0.202086910579844 36619 1410.83 12.805 13.58 0.0847762266472633 Up 0.158499537709682 tra2 transformer 2, isoform G K12897|1|4e-81|301|dse:Dsec_GM20203|transformer-2 protein GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0043484//regulation of RNA splicing;GO:0048869//cellular developmental process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048232//male gamete generation;GO:0018993//somatic sex determination 44254 5147.04 8.89 10.235 0.20325577819364 Up 0.274864614978206 bab2 bric a brac 2, isoform B K09237|1|3e-39|165|api:100161247|Cys2His2 zinc finger developmental/cell cycle regulator, other - GO:0005488//binding - 14462909 336.00 0.65 0.88 0.437063805608843 Up 0.139149385814291 35731 2445.41 19.65 20.01 0.0261918547597723 Up 0.0906419231277242 sax saxophone, isoform C K13595|1|0.0|1132|dme:Dmel_CG1891|activin receptor type-1, invertebrate GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559 GO:0006810//transport;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0019827//stem cell maintenance;GO:0048592//eye morphogenesis;GO:0008595//anterior/posterior axis specification, embryo;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007447//imaginal disc pattern formation;GO:0030703//eggshell formation;GO:0030509//BMP signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006810//transport;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0019827//stem cell maintenance;GO:0048592//eye morphogenesis;GO:0008595//anterior/posterior axis specification, embryo;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007447//imaginal disc pattern formation;GO:0030703//eggshell formation;GO:0030509//BMP signaling pathway;GO:0007472//wing disc morphogenesis 318709 2285.00 2.01 2.035 0.0178332930873187 Up 0.046559239202219 CG42726 CG42726 K09228|1|2e-34|147|mcc:713173|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 117476 1396.00 0.285 0.46 0.690671941892271 Up 0.130828160084533 Gr77a gustatory receptor 77a K08471|1|0.0|803|dme:Dmel_CG32433|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 19836019 285.00 0.16 0.01 -4 Down 0.178939373926826 12798232 690.23 3.16 0.985 -1.68172892872073 Down 0.511260071324792 CG14664 CG14664, isoform C - - - - 34622 2147.00 3.155 3.075 -0.0370535947559469 Down 0.0603288865407476 Plzf promyelocytic leukemia zinc finger ortholog, isoform B K09228|1|9e-33|142|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 19836073 403.00 0.785 1.74 1.1483227469571 Up 0.345793158103289 31771 5121.72 7.095 7.105 0.00203196518222888 Up 0.0401862369568089 CG10555 CG10555, isoform B - - - - 33906 5718.00 10.43 10.29 -0.0194961756257973 Down 0.063333773609827 DLP Daxx-like protein, isoform B K02308|1|6e-29|130|xla:446279|death-associated protein 6 - - - 12798512 503.00 0.165 0.185 0.165059246270496 Up 0.0510500594373266 41733 1879.26 3.75 5.03 0.423667804422284 Up 0.331396116761326 Aats-met Methionyl-tRNA synthetase, isoform B K01874|1|0.0|1156|dme:Dmel_CG31322|methionyl-tRNA synthetase [EC:6.1.1.10] - - - 42342 1820.00 5.18 4.915 -0.0757606813459732 Down 0.101043455289922 Nup58 nucleoporin 58kD - - GO:0005215//transporter activity GO:0051169//nuclear transport 36442 5535.99 14.51 15.885 0.130617570646748 Up 0.234909523180557 Ack-like activated Cdc42 kinase-like, isoform E K08252|1|0.0|2487|dme:Dmel_CG3969|receptor protein-tyrosine kinase [EC:2.7.10.1];K08886|3|2e-77|291|tgu:100228859|tyrosine kinase, non-receptor, 2 [EC:2.7.10.1] - GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process;GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process 8674098 6453.46 34.165 38.915 0.187807230310665 Up 0.367256637168142 CanA-14F calcineurin A at 14F, isoform D K04348|1|0.0|1003|dya:Dyak_GE15960|protein phosphatase 3, catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding GO:0007126//meiosis;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0007444//imaginal disc development;GO:0006464//cellular protein modification process;GO:0007126//meiosis;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0007444//imaginal disc development;GO:0006464//cellular protein modification process 40079 3046.51 14.02 14.495 0.0480689840507738 Up 0.114119667150971 CG3797 CG3797, isoform B K00699|1|0.0|1160|dme:Dmel_CG3797|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 37447 3143.23 97.155 106.705 0.135267629866433 Up 0.326740192841104 Sdc syndecan, isoform K K06257|1|1e-142|507|dme:Dmel_CG10497|syndecan GO:0031224//intrinsic to membrane;GO:0005924//cell-substrate adherens junction GO:0004872//receptor activity;GO:0005515//protein binding GO:0007411//axon guidance;GO:0009584//detection of visible light 19834944 646.26 2.07 2.865 0.46890437125758 Up 0.271001188746533 44275 4026.00 20.93 25.19 0.267278810478532 Up 0.424283450006604 SoxN SoxNeuro, isoform B K09267|1|7e-154|545|dme:Dmel_CG18024|transcription factor SOX1/2/3/14/21 (SOX group B) - GO:0005488//binding GO:0050789//regulation of biological process;GO:0007399//nervous system development 33213 1219.00 0.81 0.31 -1.38565369249775 Down 0.260236428477084 CG13690 CG13690 K10743|1|7e-178|623|dme:Dmel_CG13690|ribonuclease H2 subunit A [EC:3.1.26.4] - GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0003676//nucleic acid binding GO:0044260 19835429 2007.00 0.025 0.025 0 - 0.0382380134724607 36883 926.00 0.21 0.1 -1.0703893278914 Down 0.11236956808876 CG5550 CG5550, isoform B K10104|1|1e-49|196|dwi:Dwil_GK15354|ficolin;K06252|2|1e-44|179|oaa:100084981|tenascin - - - 33967 1717.25 24.05 25.91 0.10747212152269 Up 0.233159424118346 x16 x16, isoform B K12896|1|2e-58|227|dme:Dmel_CG10203|splicing factor, arginine/serine-rich 7 GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding GO:0000377 39271 3183.83 9.975 7.84 -0.3474631869945 Down 0.389083344340246 CG6175 CG6175, isoform D - - - - 44702 1064.00 248.225 248.35 0.000726322847183764 Up 0.0456016378285563 Vha36-1 vacuolar H[+] ATPase 36kD subunit 1 K02149|1|2e-131|468|dya:Dyak_GE11717|V-type H+-transporting ATPase subunit D [EC:3.6.3.14] GO:0016469//proton-transporting two-sector ATPase complex GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 10178798 1539.00 0.035 0.18 2.36257007938471 Up 0.140305111610091 36935 851.88 98.335 88.165 -0.157498956762025 Down 0.355666358473121 CG11400 CG11400, isoform B - - - - 40853 853.18 63.925 65.705 0.0396229050461756 Up 0.130530973451327 CG31248 CG31248, isoform B - - GO:0016407//acetyltransferase activity - 3772581 1023.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 His1:CG33858 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 35966 1730.19 49.5 35.365 -0.48510626388909 Down 0.60299167877427 wun wunen, isoform C K01080|1|9e-174|610|dme:Dmel_CG8804|phosphatidate phosphatase [EC:3.1.3.4] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0042802//identical protein binding;GO:0016791//phosphatase activity;GO:0042802//identical protein binding;GO:0016791//phosphatase activity GO:0009790//embryo development;GO:0008354//germ cell migration;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process;GO:0009790//embryo development;GO:0008354//germ cell migration;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process 42706 1835.65 0.275 0.31 0.172836596862216 Up 0.0603288865407476 CG4704 CG4704, isoform B - - GO:0046872//metal ion binding - 3771981 1023.00 0.07 0.025 -1.48542682717024 Down 0.0803064324395721 His1:CG33819 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 14462549 1001.00 0.155 0.22 0.505235308250422 Up 0.0790516444327037 31124 2139.00 19.98 9.225 -1.11493576684466 Down 0.673457931581033 b6 b6 K11453|1|7e-07|56.2|gga:427902|chromobox protein 6 - - - 12798155 446.00 0.19 0.11 -0.788495894806288 Down 0.0929533747193237 36375 1535.00 47.945 55.6 0.213704512988467 Up 0.407277770439836 CG8818 CG8818 - - - - 34219 2044.00 1.395 0.175 -2.99483829488422 Down 0.442444855369172 CG18088 CG18088, isoform C - - - - 5740375 951.00 196.58 244.345 0.313803033493129 Up 0.539756967375512 33577 2398.00 2.55 2.08 -0.293913718717766 Down 0.187260599656584 CG8852 CG8852 K10170|1|1e-09|65.5|ecb:100054367|toll-like receptor 8;K05401|3|2e-07|58.5|tgu:100232771|toll-like recepto 3 - GO:0005488//binding - 3771803 1023.00 0.16 0.03 -2.41503749927884 Down 0.135318980319641 His1:CG33852 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 40553 4742.00 27.265 22.77 -0.259915863982651 Down 0.420585127460045 Cont contactin K06761|1|2e-137|491|rno:54279|contactin 3 GO:0005918//septate junction - GO:0007043//cell-cell junction assembly;GO:0021675//nerve development;GO:0007272;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0021782//glial cell development 40419 690.00 0.23 0.595 1.37125580725093 Up 0.218267071721041 CG14573 CG14573 - - - - 33991 5079.19 47.3 47.53 0.00699821807557853 Up 0.0618808611808216 Mnn1 menin 1, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0009314//response to radiation;GO:0043410//positive regulation of MAPK cascade;GO:0006281//DNA repair;GO:0009886//post-embryonic morphogenesis;GO:0010259//multicellular organismal aging;GO:0043409//negative regulation of MAPK cascade;GO:0006970//response to osmotic stress;GO:0048513//organ development;GO:0009314//response to radiation;GO:0043410//positive regulation of MAPK cascade;GO:0006281//DNA repair;GO:0009886//post-embryonic morphogenesis;GO:0010259//multicellular organismal aging;GO:0043409//negative regulation of MAPK cascade;GO:0006970//response to osmotic stress;GO:0048513//organ development;GO:0009314//response to radiation;GO:0043410//positive regulation of MAPK cascade;GO:0006281//DNA repair;GO:0009886//post-embryonic morphogenesis;GO:0010259//multicellular organismal aging;GO:0043409//negative regulation of MAPK cascade;GO:0006970//response to osmotic stress;GO:0048513//organ development 53431 3053.51 20.275 21.09 0.0568571806890562 Up 0.142814687623828 Best1 bestrophin 1, isoform D K13879|1|1e-113|411|xtr:394571|bestrophin-2;K13878|2|2e-112|407|gga:423124|bestrophin-1 - - - 31374 2246.00 7.415 6.135 -0.273383348791725 Down 0.295865803724739 CG2982 CG2982, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0032452//histone demethylase activity;GO:0046914//transition metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0006355//regulation of transcription, DNA-dependent;GO:0070076//histone lysine demethylation 35329 2472.64 7.995 7.34 -0.123317970637119 Down 0.173226786421873 ik2 IkappaB kinase-like 2, isoform C K00935|1|0.0|1375|dme:Dmel_CG2615| [EC:2.7.3.9];K05410|2|0.0|1321|dpo:Dpse_GA15402|TANK-binding kinase 1 [EC:2.7.11.10] GO:0043234//protein complex;GO:0043234//protein complex GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0023060;GO:0042551//neuron maturation;GO:0032989;GO:0010669//epithelial structure maintenance;GO:0030036//actin cytoskeleton organization;GO:0008356//asymmetric cell division;GO:0010952//positive regulation of peptidase activity;GO:0006950//response to stress;GO:0006464//cellular protein modification process;GO:0023060;GO:0042551//neuron maturation;GO:0032989;GO:0010669//epithelial structure maintenance;GO:0030036//actin cytoskeleton organization;GO:0008356//asymmetric cell division;GO:0010952//positive regulation of peptidase activity;GO:0006950//response to stress;GO:0006464//cellular protein modification process 39037 1095.00 0.145 0.475 1.71187461320338 Up 0.215427288337076 CG5194 CG5194, isoform B - - - - 41600 1113.00 1.14 1.775 0.638785200227303 Up 0.254127592127856 CG11656 CG11656 - - - - 33784 1127.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG14014 CG14014 - - - - 36651 2079.31 1.39 1.585 0.1893979574159 Up 0.107086250165104 NaPi-T Na[+]-dependent inorganic phosphate cotransporter, isoform B K08193|1|2e-89|330|aag:AaeL_AAEL006514|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other GO:0031224//intrinsic to membrane GO:0005436//sodium:phosphate symporter activity GO:0015698//inorganic anion transport 19835811 1061.00 6.685 6.56 -0.0272317454752691 Down 0.0651829348831066 39798 571.00 2.675 0.805 -1.73247820317389 Down 0.487220974772157 CG13042 CG13042 - - - - 31348 3773.78 3.87 3.53 -0.13266538287323 Down 0.131290450402853 CG2941 CG2941, isoform B - - - - 40937 1866.14 1.16 2.28 0.97490901903717 Up 0.360883634922731 CG2678 CG2678, isoform B K09228|1|1e-29|131|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent 36350 1191.00 0.425 0.01 -5.4093909361377 Down 0.330372473913618 Or49a odorant receptor 49a K08471|1|0.0|768|dme:Dmel_CG13158|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 192507 2997.77 36.21 34.745 -0.0595827959336081 Down 0.160315678245938 CG4747 CG4747, isoform C K00020|1|0.0|1187|dme:Dmel_CG4747|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding GO:0034641//cellular nitrogen compound metabolic process;GO:0006007//glucose catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006007//glucose catabolic process 38197 1178.69 15.6 16.54 0.084413205421664 Up 0.166919825650509 metl methyltransferase-like, isoform B K00599|1|4e-146|517|dpo:Dpse_GA12634| [EC:2.1.1.-] - GO:0016741;GO:0016741 - 39314 3246.79 9.365 8.08 -0.212923701491251 Down 0.274930656452252 Sug Sug, isoform F K10316|1|4e-15|84.0|cin:100179677|F-box protein 41 GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006810//transport;GO:0006350;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006810//transport;GO:0006350;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006810//transport;GO:0006350;GO:0010557//positive regulation of macromolecule biosynthetic process 40964 2003.54 11.74 5.99 -0.970804500321267 Down 0.609463743230749 CG18249 CG18249, isoform C K06260|1|5e-19|96.3|ecb:100060025|platelet glycoprotein V;K13023|3|3e-18|93.6|oaa:100081004|carboxypeptidase N regulatory subunit - GO:0005488//binding;GO:0005488//binding - 3355072 3774.54 34.85 38.005 0.12503057826977 Up 0.282987716285827 CG41099 CG41099, isoform E K10380|1|1e-50|202|dan:Dana_GF23392|ankyrin - GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 19836196 331.00 0.01 0.155 3.95419631038688 Up 0.171410645885616 41362 4988.00 0.265 0.28 0.0794344674944049 Up 0.0463611147800819 KP78a KP78a K08286|1|0.0|1221|dme:Dmel_CG6715|protein-serine/threonine kinase [EC:2.7.11.-];K08798|5|0.0|1028|dsi:Dsim_GD20665|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 42814 1064.00 30.985 37.875 0.289675920276066 Up 0.471767269845463 CG10208 CG10208 - - - - 42592 2087.00 28.47 26.255 -0.116850297414026 Down 0.253070928543125 CG13409 CG13409 - - - - 7354449 1848.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 39228 4629.59 1.735 1.54 -0.172005311883359 Down 0.105237088891824 klu klumpfuss, isoform D K03364|1|1e-25|119|bfo:BRAFLDRAFT_118356|cell division cycle 20-like protein 1, cofactor of APC complex;K09228|4|1e-24|115|mdo:100026465|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0030537//larval behavior;GO:0009060//aerobic respiration 35988 509.66 830.535 735.54 -0.175237166830054 Down 0.4036124686303 RpL31 ribosomal protein L31, isoform C K02910|1|2e-66|250|dya:Dyak_GE19289|large subunit ribosomal protein L31e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 19835725 508.00 0.085 0.185 1.12199052437861 Up 0.107647602694492 19835586 550.00 9.195 9.18 -0.00235542099812976 Down 0.0416061286487914 33772 888.00 46.83 51.135 0.126878062162037 Up 0.292926958129705 CG7382 CG7382 - - - - 3355167 957.00 0.61 0.68 0.156725503687453 Up 0.0708955223880597 CG41106 CG41106 - - GO:0005488//binding - 37944 780.00 22.095 12.47 -0.825258465927335 Down 0.641824065513142 CG3663 CG3663 - - - - 33001 5353.10 1.91 2.58 0.433798427387505 Up 0.24385814291375 CG15618 CG15618, isoform C - - - - 31746 2788.00 8.045 9.765 0.279527623163345 Up 0.336745476159028 Traf6 TNF-receptor-associated factor 6 K03175|1|0.0|803|dme:Dmel_CG10961|TNF receptor-associated factor 6 GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0042742//defense response to bacterium;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation 31392 2876.00 0.18 0.485 1.42998784074482 Up 0.202119931316867 CG12184 CG12184, isoform C K12822|1|1e-08|62.8|dwi:Dwil_GK19968|RNA-binding protein 25;K09093|4|2e-06|55.1|spu:575350|aryl hydrocarbon receptor;K13172|5|7e-06|53.5|dsi:Dsim_GD13454|serine/arginine repetitive matrix protein 2 - - - 39697 4172.00 0.905 1.16 0.358135108044367 Up 0.141493858142914 CG7372 CG7372 K09228|1|2e-53|212|mcc:708389|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 318104 1742.38 1.675 2.665 0.669974437414041 Up 0.316701888786158 CG32591 CG32591, isoform B - - - - 43789 3989.64 25.665 29.99 0.224679261658171 Up 0.38855501254788 Lin29 Lin29, isoform D K05850|1|2e-71|271|dsi:Dsim_GD24384|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8];K09228|2|7e-37|156|cfa:476394|KRAB domain-containing zinc finger protein - - - 40535 1887.07 9.1 11.685 0.360719283696767 Up 0.417778364813103 TwdlG TweedleG, isoform C - - - - 36748 2106.00 54.39 45.83 -0.247049140091002 Down 0.448256505085193 Iap2 inhibitor of apoptosis 2, isoform B K04725|1|0.0|986|dme:Dmel_CG8293|baculoviral IAP repeat-containing 2/3/4 GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0042742//defense response to bacterium;GO:0010466//negative regulation of peptidase activity;GO:0006959//humoral immune response;GO:0048513//organ development;GO:0043066//negative regulation of apoptotic process;GO:0042742//defense response to bacterium;GO:0010466//negative regulation of peptidase activity;GO:0006959//humoral immune response;GO:0048513//organ development;GO:0043066//negative regulation of apoptotic process 34732 3980.12 48.765 44.025 -0.147523052692941 Down 0.321985206709814 CG44085 CG44085, isoform P - - - - 38581 3020.00 8.97 11.36 0.340782944585421 Up 0.401499141460837 Aats-leu Leucyl-tRNA synthetase K01869|1|0.0|1798|dme:Dmel_CG7479|leucyl-tRNA synthetase [EC:6.1.1.4] GO:0031980 GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0007033//vacuole organization;GO:0006418//tRNA aminoacylation for protein translation 42948 4808.07 1.3 1.46 0.167456745851563 Up 0.0974441949544314 CG42331 CG42331, isoform D K10789|1|1e-78|296|tgu:100228147|myeloperoxidase [EC:1.11.1.7];K10788|2|2e-78|295|mdo:100012462|eosinophil peroxidase [EC:1.11.1.7];K00431|3|7e-77|290|bfo:BRAFLDRAFT_67515|thyroid peroxidase [EC:1.11.1.8] - GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0005506//iron ion binding;GO:0016209//antioxidant activity GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress 53573 1754.19 36.66 35.52 -0.0455752041897795 Down 0.139677717606657 Ilk integrin linked kinase, isoform B K06272|1|0.0|925|dme:Dmel_CG10504|integrin-linked kinase [EC:2.7.11.1] GO:0005924//cell-substrate adherens junction GO:0004713//protein tyrosine kinase activity;GO:0004091//carboxylesterase activity;GO:0032559 GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006464//cellular protein modification process 5740501 484.00 29.67 32.6 0.135867037638173 Up 0.291606128648791 CG34253 CG34253 - - GO:0004620//phospholipase activity GO:0044238//primary metabolic process 14462479 352.00 0.625 0.17 -1.87832144341175 Down 0.256571126667547 CG44044 CG44044 - - - - 12797922 616.00 0.07 0.15 1.09953567355091 Up 0.0979064852727513 38243 1811.70 38.015 42.7 0.167667278773744 Up 0.345264826310923 CG12024 CG12024, isoform C - - - - 38897 2444.82 21.34 23.22 0.121807796041141 Up 0.244749702813367 CG7927 CG7927, isoform C - - - - 35909 1950.38 26.67 22.37 -0.253652568491807 Down 0.410282657508916 Ance-4 Ance-4, isoform B K01283|1|0.0|1221|dme:Dmel_CG8196|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0044464//cell part GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 31096 870.00 2.345 6.485 1.46751865173632 Up 0.602199181085722 CG14787 CG14787 K13239|1|3e-12|72.4|aga:AgaP_AGAP006651|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8] - - - 44920 2375.00 645.27 575.08 -0.16614028814058 Down 0.38832386738872 Hsp70Ab Heat-shock-protein-70Ab K03283|1|0.0|1147|dme:Dmel_CG18743|heat shock 70kDa protein 1/8 GO:0015630//microtubule cytoskeleton GO:0032559 GO:0034605//cellular response to heat 35478 1635.63 80.515 87.575 0.121261499679897 Up 0.287214370624752 gus gustavus, isoform M K10343|1|0.0|667|dsi:Dsim_GD16681|SPRY domain-containing SOCS box protein 1/4 - - GO:0007309//oocyte axis specification;GO:0023033;GO:0007309//oocyte axis specification;GO:0023033;GO:0007309//oocyte axis specification;GO:0023033;GO:0007309//oocyte axis specification;GO:0023033;GO:0007309//oocyte axis specification;GO:0023033;GO:0007309//oocyte axis specification;GO:0023033 38067 6056.01 26.265 29.59 0.171968112039208 Up 0.329084665169727 klar klarsicht, isoform I - GO:0031224//intrinsic to membrane;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0031224//intrinsic to membrane;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0031224//intrinsic to membrane;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system GO:0008092//cytoskeletal protein binding;GO:0016887//ATPase activity;GO:0008092//cytoskeletal protein binding;GO:0016887//ATPase activity;GO:0008092//cytoskeletal protein binding;GO:0016887//ATPase activity;GO:0016887//ATPase activity;GO:0005515//protein binding GO:0035148//tube formation;GO:0010970//microtubule-based transport;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035148//tube formation;GO:0010970//microtubule-based transport;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035148//tube formation;GO:0010970//microtubule-based transport;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035148//tube formation;GO:0010970//microtubule-based transport;GO:0001751//compound eye photoreceptor cell differentiation 14462634 715.00 3.81 3.77 -0.0152264742246578 Down 0.0488046493197728 37966 1772.00 14.99 11.23 -0.416642455547258 Down 0.479923391890107 CG3589 CG3589 - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33842 832.00 0.29 0.385 0.408805545567329 Up 0.0907740060758156 CG13996 CG13996 - - - - 32018 968.57 9.695 7.985 -0.27994849069556 Down 0.336019019944525 CG2157 CG2157, isoform B - - - - 19835533 779.00 8.375 10.565 0.335131671702443 Up 0.390140007924977 19835506 632.00 0.13 0.24 0.884522782580064 Up 0.108076872275789 37780 983.00 8.01 7.71 -0.0550713824936756 Down 0.101802932241448 wibg within bgcn - GO:0043234//protein complex;GO:0005634//nucleus GO:0003676//nucleic acid binding GO:0000956//nuclear-transcribed mRNA catabolic process 34998 529.00 31.09 32.875 0.0805402777259629 Up 0.192345793158103 CG17996 CG17996 K01170|1|6e-06|50.1|dme:Dmel_CG31812|tRNA-intron endonuclease [EC:3.1.27.9] - - - 37963 394.00 0.54 0.505 -0.0966760194116739 Down 0.0546823405098402 Lcp9 larval cuticle protein 9 - - GO:0005214//structural constituent of chitin-based cuticle GO:0002168//instar larval development;GO:0051234//establishment of localization 32260 751.00 0.635 0.655 0.0447383147652844 Up 0.0449742438251222 Fer3HCH ferritin 3 heavy chain homologue K00522|1|2e-105|381|dme:Dmel_CG4349|ferritin heavy chain [EC:1.16.3.1] GO:0044424//intracellular part GO:0005506//iron ion binding;GO:0003824//catalytic activity GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0009267//cellular response to starvation 40978 1275.00 0.035 0.14 2 Up 0.120855897503632 CG31463 CG31463 - - - - 40867 1528.00 0.845 0.94 0.153709415395453 Up 0.0795799762250693 CG14605 CG14605, isoform E K08144|1|1e-19|60.1|cfa:491274|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6;K08145|5|4e-13|76.3|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006909//phagocytosis;GO:0006909//phagocytosis;GO:0006909//phagocytosis 41649 603.08 3.845 3.155 -0.285343592979277 Down 0.227380795139348 CG14377 CG14377, isoform B - - - - 33676 2672.00 60.66 69.2 0.190026539899916 Up 0.390040945713908 CG15630 CG15630 K06491|1|8e-24|112|tca:664545|neural cell adhesion molecule GO:0044464//cell part - GO:0009987//cellular process 19835645 1147.00 98.385 99.16 0.0113198956487752 Up 0.068187821952186 14462433 634.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 43273 1319.65 54.58 37.14 -0.55539857933872 Down 0.630960243032624 grass Gram-positive specific serine protease, isoform B K01362|1|5e-49|195|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|3|3e-42|172|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01344|5|5e-32|139|xtr:548476|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity;GO:0043169//cation binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0004175//endopeptidase activity;GO:0043169//cation binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway;GO:0042742//defense response to bacterium;GO:0019538//protein metabolic process;GO:0008592//regulation of Toll signaling pathway 8674091 4902.18 5.695 6.65 0.22365849868044 Up 0.245344076079778 CG42594 CG42594, isoform D K04923|1|1e-09|66.2|gga:419191|potassium channel subfamily K member 15;K04916|2|1e-09|65.9|mdo:100026906|potassium channel subfamily K member 5 - - GO:0006811//ion transport;GO:0006811//ion transport 31592 1092.00 0.67 1.11 0.728326675892333 Up 0.21513010170387 CG17717 CG17717, isoform B K10657|1|9e-06|51.2|bta:508949|E3 ubiquitin-protein ligase MARCH2 [EC:6.3.2.19] - - - 246520 657.00 10.675 9.28 -0.202039359380281 Down 0.279124290054154 CG30273 CG30273 - - - - 40963 1778.00 7.53 6.45 -0.223350704361311 Down 0.258717474574032 CG7800 CG7800 K06260|1|9e-20|98.6|xla:446839|platelet glycoprotein V;K04308|2|2e-16|87.8|mmu:14160|leucine-rich repeat-containing G protein-coupled receptor 5 - GO:0005488//binding - 38264 1578.00 0.56 0.71 0.342392197447078 Up 0.109298639545635 CG1139 CG1139 - GO:0031224//intrinsic to membrane - GO:0006865//amino acid transport 40633 2420.67 28.47 35.74 0.328097141299225 Up 0.502608638224805 Hph HIF prolyl hydroxylase, isoform D K09592|1|6e-150|531|dsi:Dsim_GD19772|hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.-] - GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0019842//vitamin binding GO:0060541//respiratory system development;GO:0033554//cellular response to stress;GO:0033036;GO:0008152//metabolic process;GO:0060541//respiratory system development;GO:0033554//cellular response to stress;GO:0033036;GO:0008152//metabolic process;GO:0060541//respiratory system development;GO:0033554//cellular response to stress;GO:0033036;GO:0008152//metabolic process 37254 9124.82 37.66 42.015 0.157871484181435 Up 0.330504556861709 sm smooth, isoform Z K13159|1|0.0|650|der:Dere_GG20899|heterogeneous nuclear ribonucleoprotein L - - - 32875 1454.00 2.765 3.27 0.242011155263375 Up 0.182307489103157 CG7101 CG7101 K09228|1|2e-19|97.4|mdo:100026465|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding GO:0009987//cellular process 31679 1851.00 6.015 5.495 -0.130445256226845 Down 0.160711927090213 CG15478 CG15478, isoform B - - - - 3885598 3277.16 14.98 18.75 0.323852971811854 Up 0.445482763175274 dpr13 dpr13, isoform C K06550|1|4e-06|54.3|mdo:100028028|L1 cell adhesion molecule - - - 8674015 401.00 0.635 0.595 -0.0938669234642225 Down 0.0537247391361775 CG42465 CG42465 - - - - 35829 1925.00 2.17 0.03 -6.17658873172332 Down 0.64330999867917 Mal-A7 maltase A7, isoform B K01187|1|0.0|1172|dme:Dmel_CG11669|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding GO:0044238//primary metabolic process 42414 1534.52 35.545 28.4 -0.323755705149086 Down 0.496301677453441 Sirt2 Sirt2, isoform B K11412|1|0.0|733|dme:Dmel_CG5085|NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] - GO:0004407//histone deacetylase activity;GO:0046914//transition metal ion binding;GO:0051287//NAD binding GO:0016458//gene silencing;GO:0010259//multicellular organismal aging;GO:0048812//neuron projection morphogenesis;GO:0006464//cellular protein modification process 34870 5860.00 0.04 0.07 0.807354922057604 Up 0.0629375247655528 CG3491 CG3491 - - GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0032559 - 31683 1963.71 23.135 25.21 0.123919019293244 Up 0.249933958525954 Pdp pyruvate dehydrogenase phosphatase, isoform B K01090|1|0.0|931|dme:Dmel_CG12151|protein phosphatase [EC:3.1.3.16];K01102|3|8e-87|321|mdo:100029761|pyruvate dehydrogenase phosphatase [EC:3.1.3.43] - - - 10178829 1176.00 3.31 3.245 -0.0286127388080792 Down 0.0548144234579316 5740493 623.00 0.515 0.58 0.171480467944354 Up 0.0680227182670717 CG34258 CG34258 - - - - 38920 1733.00 0.635 0.85 0.420706249365536 Up 0.132380134724607 CG8006 CG8006 - - - - 32392 3684.00 0.075 0.01 -2.90689059560852 Down 0.100680227182671 CG9411 CG9411 - - - - 35243 657.00 1.045 1.315 0.33155985721142 Up 0.145357284374587 CG31697 CG31697 K00993|1|1e-72|271|dya:Dyak_GE13266|ethanolaminephosphotransferase [EC:2.7.8.1] GO:0044464//cell part GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006644//phospholipid metabolic process 326219 2594.00 14.51 13.52 -0.10195236778456 Down 0.187227578919561 Sk2 sphingosine kinase 2 K04718|1|2e-146|520|aag:AaeL_AAEL004285|sphingosine kinase [EC:2.7.1.91] - GO:0016301//kinase activity GO:0006643//membrane lipid metabolic process;GO:0008344//adult locomotory behavior;GO:0033057;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process 38104 4593.93 48.6 36.615 -0.408521517990833 Down 0.565909391097609 CG13907 CG13907, isoform B K08190|1|1e-39|166|mdo:100014050|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14 - - GO:0006810//transport 14462734 447.00 0.01 0.23 4.52356195605701 Up 0.229362039360719 41935 3176.00 9.975 6.965 -0.518193488508455 Down 0.474706115440497 CG4221 CG4221 K10273|1|0.0|1357|dme:Dmel_CG4221|F-box and leucine-rich repeat protein 7 - - - 7354437 3222.86 71.87 57.57 -0.320072473804784 Down 0.52664773477744 CG42354 CG42354, isoform F - - - - 34474 1254.00 62.105 73 0.233187041201931 Up 0.438845595033681 CG6415 CG6415 K00605|1|0.0|772|dme:Dmel_CG6415|aminomethyltransferase [EC:2.1.2.10] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0016769//transferase activity, transferring nitrogenous groups;GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process 39929 1215.00 0.035 0.075 1.09953567355091 Up 0.0725795799762251 Or74a odorant receptor 74a K08471|1|0.0|788|dme:Dmel_CG13726|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0007166//cell surface receptor signaling pathway;GO:0023060 41288 901.00 16.505 17.5 0.0844517834971548 Up 0.169726588297451 MED7 mediator complex subunit 7 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0016251//general RNA polymerase II transcription factor activity;GO:0005488//binding GO:0006355//regulation of transcription, DNA-dependent 3772667 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 12797929 1167.00 0.085 0.115 0.436099114806673 Up 0.0616827367586845 CG43173 CG43173 - - - - 34887 2122.00 0.025 0.045 0.84799690655495 Up 0.0552767137762515 CG15269 CG15269 K09228|1|2e-59|230|ecb:100060075|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 36328 1296.00 1.095 1.505 0.458832617158529 Up 0.191817461365738 Vha36-2 vacuolar H[+] ATPase 36kD subunit 2 K02149|1|0.0|724|dme:Dmel_CG13167|V-type H+-transporting ATPase subunit D [EC:3.6.3.14] GO:0016469//proton-transporting two-sector ATPase complex GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process 35445 2708.94 30.32 28.95 -0.0667064052944928 Down 0.171047417778365 CG1832 Chromatin-linked adaptor for MSL proteins, isoform B K09228|1|3e-55|217|mmu:630579|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 38784 420.00 361.9 293.805 -0.300732159692963 Down 0.534968960507199 Dbi Diazepam-binding inhibitor, isoform B K08762|1|6e-23|105|xtr:394469|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) - GO:0008144//drug binding;GO:0030234//enzyme regulator activity;GO:0005504//fatty acid binding;GO:0008144//drug binding;GO:0030234//enzyme regulator activity;GO:0005504//fatty acid binding GO:0055082//cellular chemical homeostasis;GO:0055082//cellular chemical homeostasis 36550 4946.36 14.77 12.455 -0.245944804523953 Down 0.35553427552503 CG6701 CG6701, isoform E K13983|1|1e-57|226|spu:590861|putative helicase MOV10L1 [EC:3.6.4.13] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process 38212 663.00 0.52 8.51 4.03257560354487 Up 0.765486725663717 CG13931 CG13931, isoform B - - - - 40638 964.94 104.685 97.995 -0.0952746920546552 Down 0.252905824858011 CG1161 CG1161, isoform C - - - - 53550 1162.00 10.355 9.175 -0.174547490489937 Down 0.247952714304583 lectin-24Db lectin-24Db K06496|1|3e-13|76.3|tgu:100231450|selectin, platele;K06560|2|6e-13|75.1|nve:NEMVE_v1g238062|mannose receptor, C type - GO:0048029//monosaccharide binding - 37502 1406.00 0.03 0.04 0.415037499278844 Up 0.0473847576277902 Gr58b gustatory receptor 58b K08471|1|0.0|815|dme:Dmel_CG13495|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 31423 2183.65 25.45 25.19 -0.0148145342288168 Down 0.0628714832915071 CG6903 CG6903, isoform B K10532|1|0.0|1053|dme:Dmel_CG6903|heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78] - - - 41983 847.00 49.005 41.695 -0.23305456721572 Down 0.42458063663981 Manf mesencephalic astrocyte-derived neurotrophic factor ortholog - - - - 33484 1217.00 2.01 0.505 -1.99284020842713 Down 0.453770968168009 CG3117 CG3117 K01312|1|9e-27|120|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09630|2|4e-25|115|ecb:100064863|protease, serine, 36 [EC:3.4.21.-];K09628|3|6e-25|114|xla:397795|protease, serine 27 [EC:3.4.21.-];K01340|5|2e-24|112|rno:54271|tryptase [EC:3.4.21.59] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40066 2307.90 1.16 1.445 0.316944687373106 Up 0.147668735966187 CG14077 CG14077, isoform C K02266|1|2e-119|431|dme:Dmel_CG14077|cytochrome c oxidase subunit VIa [EC:1.9.3.1];K12855|2|1e-37|158|dsi:Dsim_GD14782|pre-mRNA-processing factor 6 GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 37557 1130.20 133.255 86.53 -0.622917359090572 Down 0.668967111345925 babos babos, isoform B - - - - 38012 4133.08 1.445 1.65 0.191396531745137 Up 0.109199577334566 Kr kruppel, isoform B K09231|1|0.0|835|dme:Dmel_CG3340|krueppel-like family, other GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity GO:0016458//gene silencing;GO:0007417//central nervous system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001654//eye development;GO:0008595//anterior/posterior axis specification, embryo;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0048598//embryonic morphogenesis;GO:0050793//regulation of developmental process 33944 2682.78 74.815 88.57 0.243490567255525 Up 0.454662528067626 homer homer, isoform G K13166|1|2e-49|197|tgu:100218451|splicing factor, arginine/serine-rich 14;K06274|2|6e-07|56.2|xla:443914|vasodilator-stimulated phosphoprotein GO:0043005//neuron projection;GO:0043005//neuron projection;GO:0043005//neuron projection GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity GO:0043412//macromolecule modification;GO:0030534//adult behavior;GO:0010033//response to organic substance;GO:0043412//macromolecule modification;GO:0030534//adult behavior;GO:0010033//response to organic substance;GO:0043412//macromolecule modification;GO:0030534//adult behavior;GO:0010033//response to organic substance 19834828 637.00 0.195 0.425 1.12398871727545 Up 0.163980980055475 41103 955.08 8.085 5.44 -0.571641122223322 Down 0.46443666622639 CG8436 insulator binding factor 1, isoform B - - - - 42633 1746.00 13.55 11.58 -0.226657598251997 Down 0.329150706643772 Nop56 Nop56 K12844|1|1e-26|121|xla:495301|U4/U6 small nuclear ribonucleoprotein PRP31 GO:0031981//nuclear lumen - - 36507 1974.39 15.505 15.165 -0.0319880279884517 Down 0.0892880729097874 CG33156 CG33156, isoform F K00858|1|0.0|846|dya:Dyak_GE13352|NAD+ kinase [EC:2.7.1.23] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0016301//kinase activity;GO:0043169//cation binding - 5740238 754.00 0.11 0.065 -0.758991900496205 Down 0.0694426099590543 CG34238 CG34238 - - - - 32487 679.00 0.415 0.07 -2.56768450928932 Down 0.231244221371021 CG42299 CG42299 - - - - 41475 2232.00 0.29 1.085 1.90357023731691 Up 0.343250561352529 CG4810 CG4810 K03251|1|0.0|989|dme:Dmel_CG4810|translation initiation factor eIF-3 subunit 7 - - - 33423 3415.14 8.365 9.6 0.198668865570166 Up 0.266972658829745 CG9866 ataxin 7, isoform D - - - - 34149 614.73 891.58 815.365 -0.128918224638498 Down 0.325056135252939 RpS13 ribosomal protein S13, isoform C K02953|1|7e-82|302|dme:Dmel_CG13389|small subunit ribosomal protein S13e GO:0015935//small ribosomal subunit;GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0008380//RNA splicing;GO:0007052//mitotic spindle organization;GO:0006412//translation;GO:0008380//RNA splicing;GO:0007052//mitotic spindle organization 32174 4045.67 0.94 1.53 0.702798991015014 Up 0.247754589882446 Muc11A mucin 11A, isoform B K02184|1|1e-25|119|hsa:56776|formin 2 - GO:0030247//polysaccharide binding GO:0006022 19835825 296.00 2.005 0.855 -1.22960591156902 Down 0.37963941355171 41191 2527.00 18.52 22.05 0.251694557184646 Up 0.39539030511161 CG8412 CG8412 K03847|1|0.0|1209|dme:Dmel_CG8412|alpha-1,6-mannosyltransferase [EC:2.4.1.130] GO:0005789//endoplasmic reticulum membrane GO:0000030//mannosyltransferase activity GO:0006497//protein lipidation;GO:0006487//protein N-linked glycosylation 36692 4455.46 18.36 9.275 -0.985146871905642 Down 0.651796328094043 scb scab, isoform B K06487|1|3e-64|247|dre:100151255|integrin alpha V;K06483|2|1e-59|232|mmu:16401|integrin alpha 4;K06584|3|2e-58|228|ecb:100056217|integrin alpha 8 GO:0005924//cell-substrate adherens junction;GO:0005887//integral to plasma membrane;GO:0005924//cell-substrate adherens junction;GO:0005887//integral to plasma membrane GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity GO:0048565//digestive tract development;GO:0016337//cell-cell adhesion;GO:0007613//memory;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0006935//chemotaxis;GO:0007160//cell-matrix adhesion;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0008306//associative learning;GO:0035272//exocrine system development;GO:0048565//digestive tract development;GO:0016337//cell-cell adhesion;GO:0007613//memory;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0006935//chemotaxis;GO:0007160//cell-matrix adhesion;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway;GO:0008306//associative learning;GO:0035272//exocrine system development 38028 1702.36 29.15 23.835 -0.290414258018183 Down 0.455091797648924 mri mrityu, isoform E K00864|1|0.0|751|dme:Dmel_CG1216|glycerol kinase [EC:2.7.1.30];K10482|2|4e-115|415|dre:557247|BTB/POZ domain-containing protein 10 GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005267//potassium channel activity GO:0048102//autophagic cell death;GO:0030001//metal ion transport;GO:0048102//autophagic cell death;GO:0030001//metal ion transport 35236 3925.00 3.81 6.94 0.865144665084939 Up 0.524567428345001 Top3alpha topoisomerase 3alpha K03165|1|0.0|1572|dme:Dmel_CG10123|DNA topoisomerase III [EC:5.99.1.2] GO:0043232 GO:0046914//transition metal ion binding;GO:0003916//DNA topoisomerase activity GO:0006261//DNA-dependent DNA replication;GO:0000725//recombinational repair 19836077 489.00 0.17 0.1 -0.765534746362977 Down 0.0870756835292564 36052 1307.00 0.09 0.07 -0.362570079384708 Down 0.0544181746136574 CG12920 CG12920 - - - - 38354 1696.23 3.31 4.52 0.44949155560797 Up 0.327301545370493 Or63a odorant receptor 63a, isoform B K08471|1|0.0|667|dpo:Dpse_GA22157|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding;GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 3355160 9156.00 8.39 9.395 0.163222350980232 Up 0.226918504821028 CG42346 CG42346, isoform D K05401|1|2e-50|202|dme:Dmel_CG5195|toll-like recepto 3;K06838|5|7e-39|164|hsa:6585|slit 1 - GO:0005488//binding - 39432 724.00 2.64 2.975 0.172351738836852 Up 0.13763043191124 ver verrocchio, isoform B - - - - 32926 3163.28 15.53 11.125 -0.481252493646179 Down 0.513307357020209 out outsiders, isoform B K08189|1|2e-21|105|mcc:713985|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13 - - GO:0008219//cell death;GO:0003006//developmental process involved in reproduction;GO:0006810//transport 37131 2486.00 289.905 213.98 -0.438104256804111 Down 0.620492669396381 Pepck phosphoenolpyruvate carboxykinase K01596|1|0.0|1278|dme:Dmel_CG17725|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] - - - 19835276 223.00 0.01 0.25 4.64385618977472 Up 0.24085325584467 34138 1407.00 6.615 7.965 0.267933205246633 Up 0.302205785233126 CG7818 CG7818 K05925|1|2e-20|100|bfo:BRAFLDRAFT_217213|mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] GO:0043231//intracellular membrane-bounded organelle GO:0016741;GO:0001071//nucleic acid binding transcription factor activity GO:0034641//cellular nitrogen compound metabolic process 19836034 1087.31 1.34 0.835 -0.68238489798372 Down 0.225927882710342 - CG44250, isoform C - - - - 39907 2790.00 6.795 5.24 -0.374906739229941 Down 0.34962356359794 Fit2 fermitin 2 K06271|1|3e-10|67.8|mdo:100016699|talin - - - 35783 4608.24 27.56 26.79 -0.0408813068619122 Down 0.118016114119667 Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain, isoform D K12488|1|0.0|2087|dme:Dmel_CG30372|Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein - GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding;GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction 41805 879.00 5.665 5.39 -0.07179068306801 Down 0.100052833179237 CG3817 CG3817 - - - - 37117 1399.22 99.05 104.545 0.0778951845915457 Up 0.213842292959979 CG5174 CG5174, isoform P - - - - 34272 1530.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 CG13114 CG13114 - - - - 32032 1924.00 0.085 0.25 1.55639334852439 Up 0.14109760929864 C901 C901 K06052|1|3e-60|233|oaa:100084421|jagged GO:0044464//cell part - GO:0009987//cellular process 43511 1180.00 0.945 1.305 0.465663572348812 Up 0.179896975300489 fig fos intronic gene - - GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0006796//phosphate-containing compound metabolic process 37486 1510.00 0.15 0.035 -2.09953567355091 Down 0.1267335886937 CG4386 CG4386 K01316|1|4e-49|196|ptr:458478|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K01312|3|4e-48|192|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09636|5|2e-47|190|bta:615090|transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 45910 2158.00 21.93 14.85 -0.562442880985465 Down 0.579381851802932 ort ora transientless K05194|1|1e-58|228|tgu:100218394|glycine receptor alpha-2 GO:0005887//integral to plasma membrane GO:0015276//ligand-gated ion channel activity;GO:0005254//chloride channel activity GO:0006810//transport;GO:0007043//cell-cell junction assembly;GO:0007267//cell-cell signaling;GO:0009266//response to temperature stimulus;GO:0007610//behavior;GO:0010033//response to organic substance 35547 1048.00 0.155 0.295 0.928446738974966 Up 0.122341830669661 CG8335 CG8335 K03249|1|1e-62|239|dan:Dana_GF16095|translation initiation factor eIF-3 subunit 5 GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding GO:0010467//gene expression 319011 3369.00 0.855 1.24 0.536343795500977 Up 0.188845595033681 CG31897 CG31897 - - - - 31445 1865.24 0.69 2.085 1.59537911666649 Up 0.431217804781403 CG4198 CG4198, isoform B - - - - 40382 4391.96 21.355 20.835 -0.035564797939593 Down 0.10890239070136 Glg1 golgi complex-localized glycoprotein 1, isoform B K06816|1|0.0|802|isc:IscW_ISCW007750|golgi apparatus protein 1 GO:0012505//endomembrane system - - 41246 2443.99 34.465 34.725 0.0108426788906809 Up 0.0628714832915071 CG12814 CG12814, isoform E - - - - 31131 717.00 0.01 0.31 4.95419631038687 Up 0.276482631092326 CG14810 CG14810, isoform B - - - - 43617 2031.24 14.915 14.155 -0.0754522284294653 Down 0.157409853387928 CG2224 CG2224, isoform B K11866|1|0.0|791|dme:Dmel_CG2224|STAM-binding protein [EC:3.1.2.15] - - - 31459 4294.03 21.53 22.075 0.0360651183685944 Up 0.109859992075023 spoon spoonbill, isoform E - - GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0007613//memory;GO:0009060//aerobic respiration;GO:0007613//memory;GO:0009060//aerobic respiration;GO:0007613//memory;GO:0009060//aerobic respiration 33854 2285.00 7.075 7.28 0.0412083024794515 Up 0.0819904900277374 Fbw5 Fbw5 K10263|1|0.0|1270|dme:Dmel_CG9144|F-box and WD-40 domain protein 5 - GO:0005488//binding - 42320 1586.00 0.12 0.535 2.15650448567999 Up 0.252443534539691 CG3739 CG3739 K01285|1|3e-49|196|dme:Dmel_CG11626|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2];K09649|2|1e-42|174|mmu:54373|protease, serine, 16 (thymus) [EC:3.4.-.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 41347 1395.67 803.86 702.895 -0.193635071538295 Down 0.418306696605468 RpL3 ribosomal protein L3, isoform H K02925|1|3e-144|511|dya:Dyak_GE26079|large subunit ribosomal protein L3e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 33358 534.00 0.61 0.685 0.16729474539764 Up 0.0753533218861445 CG17650 CG17650 - - - - 19834908 1867.00 5.35 6.115 0.192813607238878 Up 0.214304583278299 - CG45071, isoform B K01937|1|0.0|736|dsi:Dsim_GD14523|CTP synthase [EC:6.3.4.2] - GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032559 GO:0009064//glutamine family amino acid metabolic process;GO:0009209 32827 744.00 25.105 20.055 -0.324012758853355 Down 0.471701228371417 CG6290 CG6290 - - - - 31174 2337.12 42.215 32.45 -0.379537235885233 Down 0.545040285299168 CG4199 CG4199, isoform I K00530|1|1e-173|610|dme:Dmel_CG10700| [EC:1.18.1.-];K04727|2|9e-13|75.9|tca:661587|programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] GO:0044424//intracellular part GO:0030554//adenyl nucleotide binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0019725//cellular homeostasis 19835890 1101.00 0.185 0.27 0.545434136534519 Up 0.0933166028265751 2768916 1620.04 23.135 24.65 0.0915105476999782 Up 0.198817857614582 CG33303 CG33303, isoform B K12666|1|0.0|882|dme:Dmel_CG33303|oligosaccharyltransferase complex subunit alpha (ribophorin I) GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane GO:0004576//oligosaccharyl transferase activity GO:0006464//cellular protein modification process 3772336 595.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 His2B:CG33890 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 35724 1790.00 0.395 0.145 -1.44579975304953 Down 0.178510104345529 cn cinnabar K00486|1|0.0|862|dme:Dmel_CG1555|kynurenine 3-monooxygenase [EC:1.14.13.9] GO:0031966//mitochondrial membrane GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0046496//nicotinamide nucleotide metabolic process 246418 676.00 9.05 10.235 0.177521405052843 Up 0.252641658961828 CG30051 CG30051 - - - - 32908 1940.00 20.665 20.975 0.0214814469526454 Up 0.0771694624224013 CG14194 CG14194, isoform B - - - - 38736 5766.45 15.045 17.69 0.233649941357122 Up 0.359067494386475 sfl sulfateless, isoform B K02577|1|0.0|2046|dme:Dmel_CG8339|heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.1.1.- 2.8.2.-] - GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0048513//organ development;GO:0006023;GO:0060446//branching involved in open tracheal system development;GO:0001707//mesoderm formation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0048513//organ development;GO:0006023;GO:0060446//branching involved in open tracheal system development;GO:0001707//mesoderm formation 37992 1757.00 13.265 13.84 0.0612192674080287 Up 0.128945978074231 CG2790 CG2790 K09506|1|0.0|830|dme:Dmel_CG2790|DnaJ homolog subfamily A member 5 GO:0044464//cell part GO:0046914//transition metal ion binding - 19836059 422.55 1.355 2.96 1.12730432427508 Up 0.431911240258883 41541 1658.00 21.905 22.05 0.00951844112193218 Up 0.0576542068418967 CG5961 CG5961, isoform C K10295|1|0.0|887|dme:Dmel_CG5961|F-box protein 9 - - - 42841 1513.02 249.63 208.01 -0.263138437588924 Down 0.49154669132215 Rab7 Rab7, isoform C K07897|1|6e-109|394|dme:Dmel_CG5915|Ras-related protein Rab-7A GO:0005768//endosome GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0016192//vesicle-mediated transport;GO:0035556//intracellular signal transduction;GO:0007041//lysosomal transport;GO:0050658//RNA transport;GO:0048102//autophagic cell death 42610 490.00 0.095 0.21 1.14438990933518 Up 0.118082155593713 CG13862 CG13862 - - - - 252479 5919.93 25.165 27.37 0.121176836868054 Up 0.252839783383965 DIP2 DISCO interacting protein 2, isoform E - GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0005515//protein binding - 43484 5061.14 5.8 6.815 0.232660756790275 Up 0.253797384757628 DopR2 dopamine 1-like receptor 2, isoform C K04138|1|3e-49|198|xtr:780304|adrenergic receptor alpha-2A;K04165|2|8e-47|190|tca:658532|Octopamine receptor GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0001588//dopamine neurotransmitter receptor activity, coupled via Gs;GO:0001588//dopamine neurotransmitter receptor activity, coupled via Gs GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway 3772106 1063.77 9.15 10.415 0.186819190869242 Up 0.264562145027077 34712 1262.00 10.645 6.76 -0.65508079817011 Down 0.529454497424383 CG5458 CG5458 K04575|1|5e-12|72.4|spu:580872|amyotrophic lateral sclerosis 2 (juvenile) - - - 32111 3595.14 6.92 7.47 0.110336205152512 Up 0.155692775062739 CG2247 CG2247, isoform D K03083|1|3e-66|254|dpe:Dper_GL26894|glycogen synthase kinase 3 beta [EC:2.7.11.26] - - - 39108 738.46 703.585 767.05 0.124595896813827 Up 0.304847444194954 RpS9 ribosomal protein S9, isoform E K02997|1|3e-71|268|dvi:Dvir_GJ13353|small subunit ribosomal protein S9e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 40207 850.60 27.585 19.02 -0.53636673427253 Down 0.589486197331924 Ssk snakeskin, isoform B - - - - 34282 2368.44 35.79 40.04 0.161885430419609 Up 0.329480914014001 GlcAT-S GlcAT-S, isoform C K10812|1|0.0|934|dme:Dmel_CG3881|beta-1,3-glucuronyltransferase [EC:2.4.1.135 2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0015020//glucuronosyltransferase activity;GO:0015036//disulfide oxidoreductase activity;GO:0015020//glucuronosyltransferase activity;GO:0015036//disulfide oxidoreductase activity;GO:0015020//glucuronosyltransferase activity;GO:0015036//disulfide oxidoreductase activity GO:0006029//proteoglycan metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis;GO:0010259//multicellular organismal aging;GO:0018904;GO:0006029//proteoglycan metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis;GO:0010259//multicellular organismal aging;GO:0018904;GO:0006029//proteoglycan metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis;GO:0010259//multicellular organismal aging;GO:0018904 35618 1178.42 42.995 33.675 -0.352490949135877 Down 0.52711002509576 Tsp42Ei tetraspanin 42Ei, isoform B K06497|1|8e-10|65.1|aga:AgaP_AGAP007209|CD63 antigen;K06489|4|2e-08|60.5|xla:495154|CD53 antigen GO:0031224//intrinsic to membrane - - 246426 670.00 0.9 1.02 0.180572245641821 Up 0.0874719323735306 CG30060 CG30060 - GO:0016020//membrane GO:0043492//ATPase activity, coupled to movement of substances;GO:0022892;GO:0016820//hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;GO:0000166//nucleotide binding GO:0008152//metabolic process 38726 4135.00 37.03 32.305 -0.196937074468252 Down 0.376667547219654 Mdr65 multiple drug resistance 65 K01509|1|0.0|2281|dpo:Dpse_GA10136|adenosinetriphosphatase [EC:3.6.1.3];K05658|2|0.0|1215|aag:AaeL_AAEL010379|ATP-binding cassette, subfamily B (MDR/TAP), member 1 GO:0016021//integral to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 42327 8593.86 26.48 29.13 0.137602579333131 Up 0.28695020472857 Dys dystrophin, isoform L K10366|1|0.0|854|spu:373242|dystrophin GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232 GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0005198//structural molecule activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding GO:0006810//transport;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0006810//transport;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0006810//transport;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0006810//transport;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0006810//transport;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048513//organ development;GO:0003002//regionalization;GO:0019725//cellular homeostasis;GO:0035146;GO:0010551 31156 2378.67 10.39 9.705 -0.0983955361905485 Down 0.165929203539823 eIF2B-epsilon eIF2B-epsilon, isoform B K03240|1|0.0|1281|dme:Dmel_CG3806|translation initiation factor eIF-2B epsilon subunit - - - 31706 1469.00 30.755 27.6 -0.156152708938079 Down 0.316206577730815 Ykt6 YKT6 ortholog K08516|1|8e-109|394|dya:Dyak_GE15747|synaptobrevin homolog YKT6 - - - 2768719 5904.22 2.43 3.29 0.437131270129461 Up 0.277176066569806 luna luna, isoform D K09207|1|0.0|722|dme:Dmel_CG33473|krueppel-like factor 6/7 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 19835838 1067.70 5.31 3.3 -0.686245836558338 Down 0.434684982168802 117345 1381.00 0.17 0.095 -0.839535327806754 Down 0.0879012019548276 Gr47b gustatory receptor 47b K08471|1|0.0|741|dme:Dmel_CG30030|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007606//sensory perception of chemical stimulus 40017 1029.00 20.24 33.485 0.726305678017845 Up 0.648824461761986 CG4306 CG4306 K00682|1|5e-27|121|bta:533374|gamma-glutamylcyclotransferase [EC:2.3.2.4] - - - 34189 2725.86 40.29 30.06 -0.422576796232234 Down 0.563399815083873 Acer Angiotensin-converting enzyme-related, isoform B K01283|1|0.0|1311|dme:Dmel_CG10593|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0009608//response to symbiont;GO:0006997//nucleus organization;GO:0009653//anatomical structure morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0048513//organ development 39483 3862.00 15.305 19.03 0.314272516747031 Up 0.438911636507727 SRm160 SRm160 K13171|1|0.0|742|dme:Dmel_CG11274|serine/arginine repetitive matrix protein 1 - - GO:0006396//RNA processing 10178897 373.00 0.355 0.16 -1.14974711950468 Down 0.149716021661603 CG42717 CG42717 K06238|1|8e-06|48.5|gga:396548|collagen, type VI, alpha - - - 43591 2140.68 75.19 49.91 -0.591211897561743 Down 0.649749042398626 CG9747 CG9747, isoform B K00507|1|0.0|934|dme:Dmel_CG9747|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] GO:0031224//intrinsic to membrane GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0006631//fatty acid metabolic process 19835634 310.00 1.46 0.705 -1.05027320648122 Down 0.305507858935411 31606 1647.00 0.695 1.055 0.602158115983678 Up 0.186269977545899 CG4095 CG4095 K01679|1|0.0|950|dme:Dmel_CG4095|fumarate hydratase, class II [EC:4.2.1.2] - - - 42628 943.00 25.785 12.395 -1.05677377411249 Down 0.683562277110025 CG13856 CG13856 - - - - 37009 3436.27 43.32 37.325 -0.214890982586424 Down 0.397437590807027 HPS4 Hermansky-Pudlak syndrome 4 ortholog, isoform B - - - - 19835770 686.00 0.185 0.35 0.919829651316017 Up 0.131587637036059 14462376 1645.00 1.12 1.435 0.357552004618084 Up 0.15929203539823 41431 2105.58 57.625 62.145 0.108943475496301 Up 0.263571522916392 glo glorund, isoform C K12898|1|9e-68|258|dsi:Dsim_GD20630|heterogeneous nuclear ribonucleoprotein F/H GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0006412//translation;GO:0006996//organelle organization;GO:0019094//pole plasm mRNA localization;GO:0007310//oocyte dorsal/ventral axis specification;GO:0006412//translation;GO:0006996//organelle organization;GO:0019094//pole plasm mRNA localization;GO:0007310//oocyte dorsal/ventral axis specification;GO:0006412//translation;GO:0006996//organelle organization;GO:0019094//pole plasm mRNA localization;GO:0007310//oocyte dorsal/ventral axis specification 2768909 6261.00 3.145 3.56 0.178817224087109 Up 0.15499933958526 CG15744 CG15744 K08462|1|7e-65|250|xla:399052|G protein-coupled receptor 125;K08461|2|3e-61|238|mdo:100032934|G protein-coupled receptor 124 GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 32673 1636.21 7.31 9.94 0.443374445609849 Up 0.440397569673755 CG13004 CG13004, isoform D - - - - 40247 1305.00 0.85 0.29 -1.55140994101013 Down 0.280379078061022 CG13247 CG13247 - - - - 43218 4092.66 13.37 14.165 0.0833311362847456 Up 0.159126931713116 CG6420 CG6420, isoform B K12602|1|2e-07|58.9|tca:664186|WD repeat-containing protein 61;K03130|3|3e-06|55.1|cin:100184951|transcription initiation factor TFIID subunit D4 - - - 41568 865.61 47.54 22.69 -1.0670852942701 Down 0.711398758420288 NijC ninjurin C, isoform G - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0009987//cellular process;GO:0009888//tissue development;GO:0009888//tissue development;GO:0009888//tissue development 5740713 660.00 0.365 0.41 0.167727445738067 Up 0.0647866860388324 CG34269 CG34269 - - - - 34256 1901.19 512.885 473.03 -0.116703694888384 Down 0.303361511028926 Aldh aldehyde dehydrogenase, isoform B K00128|1|0.0|1045|dme:Dmel_CG3752|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] GO:0031980 GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity GO:0010033//response to organic substance;GO:0032787//monocarboxylic acid metabolic process 318133 1573.00 38.83 40.84 0.072811158969324 Up 0.181581032888654 CG32638 CG32638 - - - - 3346207 2777.00 28.735 37.915 0.399959673743805 Up 0.54900277374191 CG33543 CG33543 K06491|1|3e-20|100|bfo:BRAFLDRAFT_122460|neural cell adhesion molecule - - - 37000 5377.00 25.71 10.145 -1.341560745077 Down 0.710210011887465 CG10936 CG10936 - - - - 33073 901.00 0.865 0.34 -1.34716538638639 Down 0.264562145027077 Ser6 serine protease 6 K01362|1|3e-132|471|dme:Dmel_CG2071| [EC:3.4.21.-];K11997|2|8e-31|134|ame:409206|tripartite motif-containing protein 2/3;K01312|3|8e-31|134|dpo:Dpse_GA14937|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40068 988.00 0.085 0.355 2.06228427825434 Up 0.197199841500462 CG18223 CG18223, isoform C K01362|1|5e-34|144|dme:Dmel_CG3795| [EC:3.4.21.-];K01312|4|8e-22|104|dpo:Dpse_GA11598|trypsin [EC:3.4.21.4];K09633|5|3e-21|102|gga:418528|transmembrane protease, serine 2 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36412 1617.00 11.085 14.41 0.37846156530744 Up 0.455091797648924 Cyp9h1 Cyp9h1 K00517|1|0.0|974|dme:Dmel_CG17577| [EC:1.14.-.-];K07424|3|2e-156|552|dvi:Dvir_GJ20172|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 3772538 1030.26 24.745 20.945 -0.240531158000479 Down 0.394366662263902 42245 4748.00 51.4 62.97 0.29289630793207 Up 0.495046889446572 CG7708 CG7708, isoform B K03307|1|2e-10|68.6|oaa:100073555|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0042136//neurotransmitter biosynthetic process;GO:0030001//metal ion transport;GO:0006865//amino acid transport;GO:0042136//neurotransmitter biosynthetic process;GO:0030001//metal ion transport;GO:0006865//amino acid transport 42528 832.08 107.485 74.56 -0.527661574379198 Down 0.641295733720777 CG3301 CG3301, isoform C K11166|1|8e-13|74.7|cfa:479531|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 59227 501.62 16.19 26.7 0.721736756272351 Up 0.634790648527275 CG17376 CG17376, isoform C - - - - 319030 819.00 0.625 0.695 0.15315678806142 Up 0.0705653150178312 CG31924 CG31924 - - - - 35393 834.02 1.29 1.395 0.112894056405934 Up 0.0762779025227843 CG31624 CG31624, isoform C K05760|1|3e-41|168|api:100162638|paxillin - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 38020 2616.00 0.59 1.115 0.918256850558463 Up 0.247226258090081 Dic61B dynein intermediate chain at 61B, isoform B K10409|1|4e-33|143|ptr:465060|dynein intermediate chain 1, axonemal GO:0030286//dynein complex;GO:0030286//dynein complex GO:0016887//ATPase activity;GO:0016887//ATPase activity GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 5740534 413.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 CG34194 CG34194, isoform B K09564|1|5e-39|159|dan:Dana_GF11346|peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8] GO:0044464//cell part GO:0005488//binding;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 8673975 808.00 27.51 10.775 -1.35226827033975 Down 0.714139479593184 7354415 395.67 22.46 17.79 -0.336291417133442 Down 0.473649451855765 CG42246 CG42246, isoform B - - - - 37476 1387.00 7.325 5.85 -0.324392134838843 Down 0.330933826443006 Tbp TATA binding protein K03120|1|3e-151|535|dme:Dmel_CG9874|transcription initiation factor TFIID TATA-box-binding protein GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006383//transcription from RNA polymerase III promoter;GO:0006355//regulation of transcription, DNA-dependent 39256 494.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 CG14143 CG14143 - - - - 36278 4184.38 10.355 11.8 0.188459306028692 Up 0.277935543521331 CG8290 CG8290, isoform E K10779|1|1e-18|96.3|cin:778547|transcriptional regulator ATRX [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 35911 3505.75 33.115 41.105 0.3118290353465 Up 0.494254391758024 CG13743 CG13743, isoform C K13576|1|5e-11|70.9|xla:444254|sodium-coupled neutral amino acid transporter 3 GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity - 42051 2341.00 35.105 13.38 -1.39159841202832 Down 0.727479857350416 CG3590 adenylosuccinate lyase K01756|1|0.0|914|dme:Dmel_CG3590|adenylosuccinate lyase [EC:4.3.2.2] - - - 170882 942.00 1.735 1.595 -0.121379238813392 Down 0.0851935015189539 Obp56c Odorant-binding protein 56c, isoform C - - GO:0005488//binding;GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization;GO:0007600//sensory perception;GO:0051234//establishment of localization 3772292 1393.00 0.345 0.335 -0.0424352663203966 Down 0.0418702945449742 45382 2160.93 90.46 69.78 -0.374466398437037 Down 0.567230220578523 ogre optic ganglion reduced, isoform F - GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane - GO:0048731;GO:0009314//response to radiation;GO:0007165//signal transduction;GO:0048731;GO:0009314//response to radiation;GO:0007165//signal transduction 19834969 736.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 36029 1865.50 33.855 21.995 -0.622193318002868 Down 0.62465328226126 CG1441 CG1441, isoform B K13356|1|3e-108|392|aga:AgaP_AGAP002279|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 38150 1428.00 62.445 26.655 -1.22817987711154 Down 0.731805573900409 CG9186 CG9186, isoform B - - - - 39529 11754.40 4.63 6.59 0.509266271747815 Up 0.40952318055739 Hml hemolectin, isoform B K03900|1|0.0|7715|dme:Dmel_CG7002|von Willebrand factor - GO:0030247//polysaccharide binding GO:0009987//cellular process;GO:0006022 38072 2825.00 18.74 7.255 -1.36907343359244 Down 0.694294016642451 CG17181 kahuli K09219|1|2e-53|211|dre:325372|scratch GO:0044464//cell part GO:0046914//transition metal ion binding - 32401 2705.00 15.835 11.435 -0.469660501616518 Down 0.511161009113723 CG15890 CG15890, isoform B - - GO:0005488//binding GO:0006810//transport 10178934 471.00 1.935 0.79 -1.29240900796731 Down 0.383700964205521 CG42828 CG42828 K06238|1|4e-09|60.1|ecb:100066356|collagen, type VI, alpha;K03909|4|6e-08|56.2|oaa:100086245|tissue factor pathway inhibitor - - - 43766 6742.47 30.7 34.45 0.166265327334112 Up 0.335424646678114 plexB plexin B, isoform B K06821|1|0.0|3994|dme:Dmel_CG17245|plexin B;K06820|2|0.0|3809|dse:Dsec_GM23238|plexin A - - - 32769 2289.00 2.7 3.285 0.282933963271499 Up 0.206016378285563 Arp8 Actin-related protein 8 K11673|1|0.0|1107|dme:Dmel_CG7846|actin-related protein 8 GO:0043234//protein complex;GO:0000790//nuclear chromatin GO:0005488//binding;GO:0005198//structural molecule activity GO:0016568//chromatin modification;GO:0010468//regulation of gene expression 12798315 1084.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 CG43265 CG43265 - - - - 36393 2536.17 31.745 34.53 0.12132095626726 Up 0.264264958393871 CG8632 zinc transporter 49B, isoform B - GO:0044464//cell part;GO:0044464//cell part GO:0015075//ion transmembrane transporter activity;GO:0005488//binding;GO:0015075//ion transmembrane transporter activity;GO:0005488//binding GO:0006811//ion transport;GO:0006811//ion transport 40972 2135.00 21.685 21.125 -0.0377461018061941 Down 0.110949676396777 RpA-70 replication protein A 70 K07466|1|0.0|1145|dme:Dmel_CG9633|replication factor A1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0043566//structure-specific DNA binding GO:0000278//mitotic cell cycle;GO:0006260//DNA replication 37377 1809.00 0.41 0.19 -1.1096244911745 Down 0.160348698982961 dgt3 dim gamma-tubulin 3 K10352|1|3e-09|63.9|gga:417309|myosin heavy chain - - - 35935 2690.69 20.205 11.455 -0.818734892878784 Down 0.633667943468498 CG8008 CG8008, isoform B - - - GO:0006810//transport;GO:0006810//transport 12798274 918.00 0.215 0.255 0.246160587269398 Up 0.0625742966583014 318591 2149.00 0.2 0.05 -2 Down 0.141658961828028 CG31091 CG31091, isoform C K01046|1|8e-77|288|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3] - - GO:0044238//primary metabolic process 33565 3733.79 11.425 15.065 0.399006507649031 Up 0.470875709945846 msl-2 male-specific lethal 2, isoform B K13164|1|0.0|1244|dme:Dmel_CG3241|male-specific lethal 2 GO:0000805//X chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0000805//X chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0009047//dosage compensation by hyperactivation of X chromosome;GO:0009047//dosage compensation by hyperactivation of X chromosome 37216 3240.26 18.96 21.51 0.182048560524802 Up 0.320862501651037 Tab2 TAK1-associated binding protein 2, isoform C - - - - 48343 810.00 0.81 3.9 2.26748031086499 Up 0.588561616695285 deltaTry deltaTrypsin K01312|1|3e-107|387|dme:Dmel_CG30031|trypsin [EC:3.4.21.4] GO:0005576//extracellular region GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34663 1196.00 0.3 0.2 -0.584962500721156 Down 0.0978074230616827 CG5418 CG5418 K01239|1|9e-41|167|xla:379157|purine nucleosidase [EC:3.2.2.1] - - - 318578 2419.00 1.77 2.15 0.280587299506463 Up 0.165731079117686 CG31068 CG31068, isoform C - - - - 41293 1356.00 16.86 18.075 0.100391110896398 Up 0.199511293092062 mRpL37 mitochondrial ribosomal protein L37 - GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 42338 2014.00 0.04 0.42 3.39231742277876 Up 0.26367058512746 CG16727 CG16727 K08202|1|7e-61|235|aag:AaeL_AAEL012443|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 40114 507.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 CG12519 CG12519, isoform B - - - - 33249 471.00 2.625 2.165 -0.27795039782676 Down 0.1828028001585 CG12506 CG12506 - - - - 40263 1312.50 317.875 226.26 -0.490478000602011 Down 0.641163650772685 CG11796 CG11796, isoform B K00457|1|0.0|740|dse:Dsec_GM22213|4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] - GO:0016846//carbon-sulfur lyase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0043169//cation binding;GO:0016846//carbon-sulfur lyase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0043169//cation binding GO:0006520//cellular amino acid metabolic process;GO:0006520//cellular amino acid metabolic process 19835619 633.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 34014 2252.00 0.285 0.535 0.908576972236405 Up 0.165400871747457 CG5155 gudu K10056|1|4e-08|60.5|dre:30415|junction plakoglobin - - - 34035 1186.00 1.795 0.795 -1.1749570785387 Down 0.353288865407476 Spn28B serpin 28B, isoform B K13963|1|2e-92|339|dya:Dyak_GE11095|serpin B - GO:0004866//endopeptidase inhibitor activity - 318151 4702.00 0.335 0.42 0.326228232320988 Up 0.0888257825914674 CG32681 CG32681 - - - - 31030 1743.09 39.405 39.73 0.011850092233311 Up 0.0646215823537181 Sec22 Sec22 ortholog, isoform B K08517|1|4e-116|418|dme:Dmel_CG7359|vesicle transport protein SEC22 - - - 31551 1864.00 0.1 0.23 1.20163386116965 Up 0.123068286884163 vanin-like vanin-like K01435|1|0.0|1104|dme:Dmel_CG32754|biotinidase [EC:3.5.1.12] - - - 19834724 507.00 0.485 0.095 -2.35198532874354 Down 0.248348963148857 35531 1738.31 137.175 177.025 0.367935540597272 Up 0.579546955488046 CG14591 CG14591, isoform D - - - - 34590 1111.00 0.21 0.195 -0.106915203916512 Down 0.0437194558182539 Tsp33B tetraspanin 33B K07607|1|6e-08|58.5|ame:724916|peripherin GO:0031224//intrinsic to membrane - - 39390 1830.00 72.61 65.59 -0.146692377806935 Down 0.333113195086514 CAH2 carbonic anhydrase 2, isoform B K01672|1|0.0|660|dme:Dmel_CG6906|carbonic anhydrase [EC:4.2.1.1] - GO:0016836//hydro-lyase activity - 3771883 739.00 0.545 0.79 0.535596423400176 Up 0.14654603090741 CG10332 CG10332 - - - - 318854 1023.00 0.5 0.025 -4.32192809488736 Down 0.323900409457139 His1:CG31617 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 42392 1525.00 4.08 5.71 0.484921593391347 Up 0.375742966583014 trem trade embargo K09228|1|3e-39|163|hsa:353088|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 31979 2420.29 24.29 27.4 0.173813403212024 Up 0.325980715889579 PPP4R2r protein phosphatase 4 regulatory subunit 2-related protein, isoform D K11294|1|4e-09|63.9|spu:577587|nucleolin;K04573|3|6e-09|63.2|ssc:100152282|neurofilament medium polypeptide (neurofilament 3) GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex - GO:0007049//cell cycle;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0006470//protein dephosphorylation 42609 1178.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 CG7080 CG7080 - - - - 33301 646.00 19.595 22.06 0.170947217989173 Up 0.310857218333113 CG14341 CG14341 - - - GO:0048232//male gamete generation 43250 1083.00 0.395 0.085 -2.21631790692676 Down 0.215196143177916 CG6283 CG6283 K01046|1|2e-147|521|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|1|2e-147|521|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32];K01059|2|2e-37|156|dme:Dmel_CG4582|lipoprotein lipase [EC:3.1.1.34] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 43926 912.00 1.885 2.57 0.447203835925214 Up 0.247721569145423 fan farinelli K06096|1|7e-19|94.4|dre:436819|vesicle-associated membrane protein-associated protein A GO:0016020//membrane - - 34166 1547.00 2.895 2.78 -0.0584784652657291 Down 0.0690463611147801 fy fuzzy, isoform B K12617|1|2e-23|111|bfo:BRAFLDRAFT_119484|DNA topoisomerase 2-associated protein PAT1 GO:0043232 - GO:0001736//establishment of planar polarity;GO:0009987//cellular process 43652 733.00 75.085 85.88 0.193797467039857 Up 0.396248844274204 dj-1beta dj-1beta K05687|1|2e-84|311|dpo:Dpse_GA12322|protein DJ-1;K03152|3|8e-57|219|aag:AaeL_AAEL004081|4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis - - GO:0006950//response to stress;GO:0007626//locomotory behavior 38145 1600.00 56.86 48.345 -0.234047409896826 Down 0.430623431514991 scf supercoiling factor, isoform B K02183|1|6e-08|58.9|ecb:100057133|calmodulin GO:0005694//chromosome;GO:0005694//chromosome GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding GO:0051276//chromosome organization;GO:0007549//dosage compensation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0051276//chromosome organization;GO:0007549//dosage compensation;GO:0010557//positive regulation of macromolecule biosynthetic process 41184 4429.00 21.2 25.82 0.284424735856629 Up 0.43778893144895 CG12950 CG12950, isoform B K06764|1|3e-16|88.2|ecb:100053098|contactin 6;K06491|2|6e-16|87.0|bta:535613|neural cell adhesion molecule;K06467|5|2e-15|85.1|ptr:450167|CD22 antigen GO:0044464//cell part - - 38839 1621.00 0.03 0.07 1.22239242133645 Up 0.0727446836613393 mthl6 methuselah-like 6 K04599|1|3e-98|358|dpo:Dpse_GA19967|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0010259//multicellular organismal aging 37522 981.14 1.92 0.96 -1 Down 0.340212653546427 CG30280 CG30280, isoform C K10104|1|3e-47|188|dwi:Dwil_GK15354|ficolin GO:0044421//extracellular region part;GO:0044421//extracellular region part GO:0005515//protein binding;GO:0005515//protein binding GO:0023060;GO:0023060 38613 1220.41 162.155 175.91 0.117463988847384 Up 0.297252674679699 Uev1A Uev1A, isoform C K10704|1|1e-74|280|dya:Dyak_GE20564|ubiquitin-conjugating enzyme E2 variant GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity GO:0048869//cellular developmental process;GO:0006281//DNA repair;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0006351//transcription, DNA-dependent;GO:0060255;GO:0006464//cellular protein modification process 32441 1872.00 12.44 12.59 0.0172917975884139 Up 0.0642253335094439 CG5599 CG5599 K09699|1|0.0|815|dme:Dmel_CG5599|2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] GO:0005759//mitochondrial matrix GO:0005488//binding;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups GO:0006909//phagocytosis;GO:0035337;GO:0009060//aerobic respiration 32041 1322.57 61.415 69.135 0.170825205916398 Up 0.362237485140668 CG2076 CG2076, isoform B K06890|1|2e-07|57.4|api:100165572| GO:0031224//intrinsic to membrane - - 2768889 1733.00 0.175 0.055 -1.66985139830767 Down 0.1232664113063 CG33253 CG33253, isoform C K03364|1|4e-18|93.2|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0031224//intrinsic to membrane - GO:0006909//phagocytosis 12798390 487.00 0.775 0.305 -1.34538706771135 Down 0.251122705058777 CG43200 CG43200 - - - - 31017 8967.96 7.97 9.02 0.178547709264909 Up 0.240490027737419 sdk sidekick, isoform I K06252|1|1e-97|360|bfo:BRAFLDRAFT_124749|tenascin GO:0016021//integral to membrane;GO:0016021//integral to membrane - GO:0001745//compound eye morphogenesis;GO:0045665//negative regulation of neuron differentiation;GO:0001745//compound eye morphogenesis;GO:0045665//negative regulation of neuron differentiation 42013 1644.00 0.555 0.465 -0.255257055242075 Down 0.0834764231937657 CG14891 CG14891 K13125|1|2e-42|174|dsi:Dsim_GD17393|nitric oxide synthase-interacting protein;K10280|2|2e-06|53.9|spu:579578|F-box and leucine-rich repeat protein 14;K10275|3|3e-06|53.5|aga:AgaP_AGAP011930|F-box and leucine-rich repeat protein 9;K10279|5|7e-06|52.4|mcc:695089|F-box and leucine-rich repeat protein 13 - - - 35843 3598.23 8.78 10.29 0.22895013735861 Up 0.299729229956413 rgr regular, isoform C K09228|1|9e-43|176|api:100159445|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 32088 5723.12 24.48 27.03 0.142957953842043 Up 0.28440760797781 Evi5 ecotropic viral integration site 5 ortholog, isoform E K11837|1|1e-13|79.3|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K11498|2|6e-09|63.9|aga:AgaP_AGAP006472|centromeric protein E;K10352|3|7e-09|63.5|spu:580674|myosin heavy chain;K09291|4|1e-08|62.8|phu:Phum_PHUM136010|nucleoprotein TPR;K06102|5|1e-08|62.8|xtr:100145755|cingulin GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 14462726 632.00 0.195 0.64 1.71459778113775 Up 0.250990622110686 CG43796 CG43796 - - - - 37601 2064.00 14.705 17.42 0.244437839711801 Up 0.366992471271959 RYBP ring and YY1 binding protein, isoform B K11468|1|2e-70|267|dme:Dmel_CG12190|YY1-associated factor 2 GO:0044451//nucleoplasm part GO:0046914//transition metal ion binding - 32532 1367.06 152.83 160.1 0.0670455406388328 Up 0.197860256240919 CG8974 CG8974, isoform E K10666|1|9e-144|509|dme:Dmel_CG8974|E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 2768859 879.00 0.1 0.28 1.48542682717024 Up 0.149716021661603 CG33226 CG33226 K09632|1|2e-19|95.9|hsa:1506|chymotrypsin-like protease [EC:3.4.21.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides - 246404 811.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 CG30031 CG30031 K01312|1|3e-107|387|dme:Dmel_CG30031|trypsin [EC:3.4.21.4] GO:0005576//extracellular region GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33037 643.00 3.34 3.38 0.0171751438081322 Up 0.0488046493197728 Obp19a Odorant-binding protein 19a - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization;GO:0010033//response to organic substance;GO:0007635//chemosensory behavior 41145 5799.09 44.11 52.525 0.251898496468191 Up 0.447464007396645 mura murashka, isoform C K11980|1|5e-10|67.8|cbr:CBG00875|E3 ubiquitin-protein ligase RNF11;K11982|3|2e-09|65.9|dme:Dmel_CG11982|E3 ubiquitin-protein ligase RNF115/126 [EC:6.3.2.19] - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0007611//learning or memory;GO:0007611//learning or memory;GO:0007611//learning or memory 53566 2583.54 19.145 16.33 -0.229442869288466 Down 0.364548936732268 Kat60 katanin 60, isoform B K07767|1|0.0|983|dme:Dmel_CG10229|microtubule-severing ATPase [EC:3.6.4.3] - GO:0016462//pyrophosphatase activity;GO:0032559 - 38134 1187.00 1.51 2.545 0.753117106750616 Up 0.332452780346057 CG9192 CG9192 - - - - 32784 3573.00 0.03 0.04 0.415037499278844 Up 0.0473847576277902 CG15373 CG15373, isoform B - - - - 36799 2247.61 13.49 12.065 -0.161062432732516 Down 0.25891559899617 CG15706 CG15706, isoform F K10316|1|3e-19|97.4|cin:100179677|F-box protein 41 - - - 40271 2277.00 5.825 6.765 0.215831884434895 Up 0.242834500066041 CG5130 zinc transporter 77C, isoform B K03295|1|4e-39|163|aag:AaeL_AAEL014902|cation efflux system protein, CDF family GO:0044464//cell part;GO:0044464//cell part GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0006811//ion transport 32399 1338.24 27.84 22.4 -0.313660478903762 Down 0.470446440364549 CG5321 CG5321, isoform C K00471|1|0.0|855|dme:Dmel_CG5321|gamma-butyrobetaine dioxygenase [EC:1.14.11.1] - GO:0003824//catalytic activity GO:0008152//metabolic process 35081 1553.00 0.59 0.765 0.374744793330811 Up 0.121021001188747 CG5755 CG5755 - GO:0031224//intrinsic to membrane - GO:0006810//transport 32454 1254.26 0.59 0.985 0.739408770094535 Up 0.206610751551975 CG9106 CG9106, isoform B - - - - 246582 952.00 108.125 138.23 0.354370624469387 Up 0.563663980980055 CG30382 CG30382, isoform B K02730|1|2e-136|484|dme:Dmel_CG30382|20S proteasome subunit alpha 1 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 42059 3729.76 12.94 14.09 0.122833994317129 Up 0.21328094043059 Dad daughters against dpp, isoform C K04677|1|0.0|1100|dme:Dmel_CG5201|SMAD, mothers against DPP 6/7 - - - 34876 1149.00 4.62 4.61 -0.0031261009867197 Down 0.0401862369568089 l(2)35Bc lethal (2) 35Bc, isoform B K10761|1|9e-166|582|dme:Dmel_CG4103|tRNA(His) guanylyltransferase [EC:2.7.7.-] - GO:0016740//transferase activity;GO:0016740//transferase activity - 39613 7944.48 15.415 16.845 0.127985539014582 Up 0.238013472460705 CG9425 CG9425, isoform D K13983|1|6e-50|201|nve:NEMVE_v1g93294|putative helicase MOV10L1 [EC:3.6.4.13] GO:0044464//cell part;GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0032559 - 53583 1743.00 0.115 0.065 -0.823122237915921 Down 0.07657508915599 Ugt37c1 UDP-glycosyltransferase 37c1 K00699|1|0.0|938|dme:Dmel_CG8652|glucuronosyltransferase [EC:2.4.1.17] - GO:0008194//UDP-glycosyltransferase activity - 40461 4256.16 22.785 23.155 0.0232393864804537 Up 0.0795139347510236 srpk79D serine-arginine protein kinase at 79D, isoform O K08832|1|0.0|939|dpo:Dpse_GA11029|serine/threonine kinase 23 [EC:2.7.11.1];K08831|2|3e-131|470|api:100158890|SFRS protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 37675 505.00 1.17 1.98 0.758991900496205 Up 0.297450799101836 CG13545 CG13545 - - - - 40998 3003.00 20.37 15.65 -0.380283323145907 Down 0.491216483951922 Atg13 Autophagy-specific gene 13 - - - GO:0044248//cellular catabolic process 36232 969.54 175.21 153.185 -0.193810083891207 Down 0.408796724342887 Sod3 superoxide dismutase 3, isoform E K04565|1|8e-105|379|dme:Dmel_CG9027|Cu/Zn superoxide dismutase [EC:1.15.1.1] - GO:0003824//catalytic activity;GO:0016209//antioxidant activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0016209//antioxidant activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0016209//antioxidant activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0016209//antioxidant activity;GO:0043169//cation binding GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0006800//oxygen and reactive oxygen species metabolic process;GO:0006800//oxygen and reactive oxygen species metabolic process 2768686 773.79 30.415 19.06 -0.674234884962062 Down 0.629474309866596 CG33494 CG33494, isoform B - - - - 14462605 3882.11 24.83 21.96 -0.177206207171642 Down 0.329381851802932 Rgk1 Rad, Gem/Kir family member 1, isoform C K07847|1|4e-07|57.4|tca:664242|Rad and Gem related GTP binding protein 1 - - - 3355111 7395.00 0.625 0.815 0.382943869568991 Up 0.125049531105534 CG17374 CG17374 K00665|1|0.0|4624|dme:Dmel_CG17374|fatty acid synthase, animal type [EC:2.3.1.85] - GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0022892 GO:0008152//metabolic process 326168 1300.00 14.075 14.85 0.0773280087205362 Up 0.158499537709682 Mulk Multi-substrate lipid kinase K09881|1|3e-32|139|dre:334270|acylglycerol kinase [EC:2.7.1.94] - GO:0016301//kinase activity GO:0007186//G-protein coupled receptor signaling pathway 12798214 491.00 0.17 0.19 0.160464672193246 Up 0.0504556861709153 CG43052 CG43052 - - - - 34052 858.00 4851.18 2950.11 -0.717566961943256 Down 0.704266279223352 Acp1 adult cuticle protein 1 - - - - 19835930 684.00 0.24 0.22 -0.125530882083859 Down 0.0491348566900013 42391 1220.00 1.66 1.82 0.132755208851771 Up 0.0922929599788667 CG4854 CG4854 K09230|1|2e-36|153|ptr:456317|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 45339 2113.33 3.835 3.76 -0.0284939158252961 Down 0.0585787874785365 net net, isoform C K09084|1|2e-18|94.7|mdo:100025431|atonal protein 8 GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression 41778 1530.90 13.325 14.295 0.10137508698456 Up 0.185807687227579 Hexim HEXIM ortholog, isoform B - - - - 32338 1301.00 6.725 6.99 0.0557581879314502 Up 0.09731211200634 Rtc1 Rtc1 K11108|1|0.0|743|dme:Dmel_CG11130|RNA 3'-terminal phosphate cyclase-like protein GO:0043231//intracellular membrane-bounded organelle - - 31362 2136.47 9.805 10.18 0.0541480258835465 Up 0.106392814687624 Tip60 Tip60, isoform C K11304|1|0.0|1030|dme:Dmel_CG6121|histone acetyltransferase HTATIP [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0046914//transition metal ion binding;GO:0016746//transferase activity, transferring acyl groups GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0006325//chromatin organization 38560 2910.00 0.295 0.26 -0.182203331220749 Down 0.0562343151499141 CG11353 CG11353, isoform B K00680|1|5e-17|90.5|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups;GO:0016746//transferase activity, transferring acyl groups - 12798361 1315.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 12798409 613.00 0.07 1.11 3.9870609442925 Up 0.441454233258486 38757 1394.00 9.92 9.425 -0.0738475022308484 Down 0.127889314489499 CG9948 CG9948, isoform C K09427|1|2e-07|57.4|dpo:Dpse_GA13983|Adh transcription factor 1 - - - 31907 4110.99 36.41 42.23 0.213933506356788 Up 0.395885616166953 l(1)G0232 lethal (1) G0232, isoform I K01104|1|0.0|914|dme:Dmel_CG32697|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process 3885608 939.00 0.25 0.165 -0.599462070416271 Down 0.0898494254391758 37392 1161.00 0.235 0.85 1.85480208446006 Up 0.302436930392286 Cht9 Cht9 K01183|1|0.0|708|dme:Dmel_CG10531|chitinase [EC:3.2.1.14] - - - 39807 468.00 1.85 2.235 0.272749560667006 Up 0.163188482366926 CG33060 CG33060 - - - - 41084 3108.00 14.775 16.01 0.115815177451362 Up 0.218498216880201 tgo tango, isoform B K09097|1|0.0|1112|dme:Dmel_CG11987|hypoxia-inducible factor 1 beta GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0023060;GO:0060541//respiratory system development;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0010551 42502 1477.00 5.945 4.68 -0.345168280162251 Down 0.3183529256373 ppan peter pan K08387|1|7e-74|278|ecb:100058380|purinergic receptor P2Y, G protein-coupled, 11 - - GO:0009791//post-embryonic development;GO:0007292//female gamete generation 12798425 641.00 0.26 0.475 0.869415890189856 Up 0.15291903315282 CG43204 CG43204 - - - - 37148 1950.00 25.825 23.88 -0.112965512487617 Down 0.235074626865672 Gint3 GDI interacting protein 3, isoform E K14011|1|0.0|751|dme:Dmel_CG5469|UBX domain-containing protein 6 - - - 3354994 2632.48 13.915 15.65 0.169521748488373 Up 0.282987716285827 su(f) suppressor of forked, isoform G K13217|1|4e-15|84.0|nvi:100123653|pre-mRNA-processing factor 39;K12869|5|8e-13|76.3|tca:661183|crooked neck GO:0005849//mRNA cleavage factor complex;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006396//RNA processing 39429 6072.00 0.07 0.14 1 Up 0.0917316074494783 sti sticky, isoform B K08282|1|0.0|3423|dme:Dmel_CG10522|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0015629//actin cytoskeleton GO:0043169//cation binding;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0032559 GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0051276//chromosome organization;GO:0023033;GO:0000920//cytokinetic cell separation;GO:0006464//cellular protein modification process 44748 1349.00 8.815 9.235 0.0671513916622563 Up 0.120525690133404 NiPp1 nuclear inhibitor of protein phosphatase 1 K13216|1|4e-94|345|tca:656775|nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-] GO:0016604//nuclear body GO:0003723//RNA binding;GO:0004864//protein phosphatase inhibitor activity GO:0006470//protein dephosphorylation;GO:0006935//chemotaxis 19835684 701.00 0.4 0.265 -0.594007640324163 Down 0.113723418306697 49809 3706.09 42.03 45.1 0.101707976990769 Up 0.238442742042002 Rbp2 RNA-binding protein 2, isoform E K03258|1|4e-09|63.9|tad:TRIADDRAFT_53556|translation initiation factor eIF-4B GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0006412//translation;GO:0006412//translation 38820 1536.29 72.445 63.285 -0.195022533192838 Down 0.403216219786026 Sh3beta Sh3beta, isoform E - - - - 14462677 252.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 14462840 347.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 CG43886 CG43886 - - - - 42946 6338.00 0.125 0.255 1.02856915219677 Up 0.121780478140272 asp abnormal spindle K10360|1|2e-10|69.7|dre:100006612|myosin IX;K10388|5|7e-10|67.8|cfa:482083|plectin GO:0015630//microtubule cytoskeleton;GO:0044430//cytoskeletal part GO:0016301//kinase activity;GO:0015631//tubulin binding;GO:0017022//myosin binding GO:0000278//mitotic cell cycle;GO:0007293//germarium-derived egg chamber formation;GO:0051640//organelle localization;GO:0007015//actin filament organization;GO:0022402//cell cycle process;GO:0051276//chromosome organization;GO:0042078//germ-line stem cell division;GO:0000226//microtubule cytoskeleton organization 40681 1577.03 25.745 30.425 0.240964992803634 Up 0.408301413287545 CG1427 CG1427, isoform E K03341|1|0.0|948|dme:Dmel_CG1427|O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] GO:0044424//intracellular part GO:0048037//cofactor binding GO:0006412//translation 43242 7734.55 9.74 10.25 0.0736302323104661 Up 0.129804517236825 CG5521 CG5521, isoform B K07207|1|8e-22|107|bfo:BRAFLDRAFT_64809|tuberous sclerosis 2 GO:0044464//cell part;GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0009966//regulation of signal transduction;GO:0009966//regulation of signal transduction 3772520 164.00 1.03 1 -0.0426443374084937 Down 0.0480451723682473 35830 1814.00 1.125 0.01 -6.81378119121704 Down 0.528695020472857 Mal-A8 maltase A8 K01187|1|0.0|1184|dme:Dmel_CG8690|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding GO:0044238//primary metabolic process 38710 615.00 24.555 9.075 -1.4360472743122 Down 0.714139479593184 Acp65Aa adult cuticle protein 65Aa - - GO:0042302//structural constituent of cuticle - 318893 991.00 0.55 0.88 0.678071905112637 Up 0.180392286355831 CG33127 CG33127 K01312|1|3e-24|112|ssc:100302368|trypsin [EC:3.4.21.4];K01324|2|3e-24|112|cfa:475624|plasma kallikrein [EC:3.4.21.34];K09634|3|6e-24|111|dre:100003261|transmembrane protease, serine 3 [EC:3.4.21.-];K01323|4|1e-23|110|mdo:100013939|coagulation factor XI [EC:3.4.21.27] - GO:0003824//catalytic activity GO:0019538//protein metabolic process 42369 3310.04 61.2 57.38 -0.0929836848113499 Down 0.226720380398891 CG4538 CG4538, isoform D K03544|1|0.0|1039|dme:Dmel_CG4538|ATP-dependent Clp protease ATP-binding subunit ClpX GO:0043234//protein complex;GO:0043234//protein complex GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 35840 540.00 31.745 9.755 -1.7023155999771 Down 0.742834500066041 CG14752 CG14752 - - - - 33303 1801.00 8.72 9.41 0.10986658795161 Up 0.171443666622639 CG5118 CG5118 K10380|1|6e-06|52.8|cin:100176624|ankyrin - - - 19836144 422.00 0.31 0.01 -4.95419631038687 Down 0.276482631092326 32188 1331.00 0.32 0.195 -0.714597781137752 Down 0.108605204068155 CG2577 CG2577 K02218|1|8e-108|390|dme:Dmel_CG2028|casein kinase 1 [EC:2.7.11.1];K08957|4|2e-106|385|xla:379624|casein kinase 1, alpha [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0008589//regulation of smoothened signaling pathway;GO:0006508//proteolysis;GO:0009057//macromolecule catabolic process;GO:0006464//cellular protein modification process 37916 3291.00 4.6 4.755 0.0478114799161883 Up 0.0768722757891956 Brca2 breast cancer 2, early onset homolog - GO:0043231//intracellular membrane-bounded organelle - GO:0000711//meiotic DNA repair synthesis;GO:0000724//double-strand break repair via homologous recombination;GO:0000087//M phase of mitotic cell cycle;GO:0033313 7354430 640.00 22.985 21.27 -0.111872632856132 Down 0.228701624620262 CG42392 CG42392 - - - - 35174 701.00 32.69 30.625 -0.0941395329899706 Down 0.21060626073174 CG10470 CG10470 - GO:0031224//intrinsic to membrane - - 42801 1511.48 35.555 30.325 -0.229544810925776 Down 0.408103288865407 CG10365 CG10365, isoform D K07232|1|7e-147|520|dse:Dsec_GM26525|cation transport protein ChaC GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding GO:0006732//coenzyme metabolic process;GO:0006732//coenzyme metabolic process;GO:0006732//coenzyme metabolic process;GO:0006732//coenzyme metabolic process 40160 2322.00 37.74 38.48 0.0280143761695968 Up 0.102892616563202 Kap-alpha1 karyopherin alpha1 K10590|1|1e-08|62.4|xtr:100158539|E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19] GO:0005635//nuclear envelope GO:0008565//protein transporter activity GO:0006605//protein targeting 31010 3680.00 3.92 3.375 -0.215966152177015 Down 0.18617091533483 l(1)1Bi lethal (1) 1Bi K02331|1|0.0|1955|dme:Dmel_CG6189|DNA polymerase phi subunit [EC:2.7.7.7] - - - 40254 2856.00 29.6 34.53 0.222253158337074 Up 0.396446968696341 CG13248 CG13248 K13866|1|0.0|1248|dme:Dmel_CG13248|solute carrier family 7 (cationic amino acid transporter), member 4 GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity GO:0006865//amino acid transport 41744 5111.00 14.755 16.845 0.19111650768975 Up 0.31221106855105 Afti aftiphilin, isoform D - - - - 12798227 1386.00 0.26 0.295 0.182203331220749 Up 0.0562343151499141 37636 2550.91 28.635 30.52 0.0919753587094367 Up 0.207964601769911 CG3499 CG3499, isoform D K08955|1|8e-146|518|ptr:450366|ATP-dependent metalloprotease [EC:3.4.24.-] GO:0019866//organelle inner membrane GO:0004175//endopeptidase activity;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0009987//cellular process 36580 3423.00 9.685 10.83 0.161209289005073 Up 0.239103156782459 CG8494 CG8494 K11848|1|0.0|1772|dme:Dmel_CG8494|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0048731;GO:0019941//modification-dependent protein catabolic process 19835539 385.00 6.945 4.17 -0.735927310536729 Down 0.494617619865275 5740776 1026.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 CG40992 CG40992 - GO:0043229//intracellular organelle - - 42293 1820.00 16.405 13.82 -0.247377978130161 Down 0.367487782327302 Cyp12a5 Cyp12a5 K00517|1|0.0|1045|dme:Dmel_CG11821| [EC:1.14.-.-];K10721|5|2e-45|184|dme:Dmel_CG12028|CYP302A1; ecdysteroid 22-hydroxylase GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0009636//response to toxic substance 19835780 983.00 2.985 3.365 0.172875573345512 Up 0.147833839651301 37877 2234.21 1.615 2.97 0.878928766106841 Up 0.387498348963149 CG11406 CG11406, isoform D K01046|1|5e-37|157|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|5|3e-34|148|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - - GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 42398 1391.00 524.475 714.15 0.445353123706316 Up 0.629837537973848 Rh3 rhodopsin 3 K13802|1|2e-55|216|dpe:Dper_GL12414|opsin Rh1 GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007602//phototransduction;GO:0016037;GO:0009411//response to UV 43590 1051.00 15.675 15.655 -0.00184193455073151 Down 0.0416061286487914 Bet5 BET5 ortholog - GO:0005801//cis-Golgi network - GO:0048193//Golgi vesicle transport 32855 3251.00 5.235 6.01 0.199175453780377 Up 0.218234050984018 fu fused K06228|1|0.0|1526|dme:Dmel_CG6551|fused [EC:2.7.11.1] GO:0044424//intracellular part;GO:0043234//protein complex GO:0004672//protein kinase activity;GO:0032559 GO:0007365//periodic partitioning;GO:0003006//developmental process involved in reproduction;GO:0007227//signal transduction downstream of smoothened;GO:0006464//cellular protein modification process;GO:0010608//posttranscriptional regulation of gene expression;GO:0006508//proteolysis;GO:0042307//positive regulation of protein import into nucleus 50257 466.00 0.01 0.205 4.35755200461808 Up 0.213941355171047 CG15323 karr - - - - 32751 2494.10 38.23 39.645 0.0524337255280772 Up 0.143640206049399 CG8188 CG8188, isoform D K10583|1|6e-94|345|dsi:Dsim_GD17343|ubiquitin-conjugating enzyme E2 S [EC:6.3.2.19] GO:0000152//nuclear ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex GO:0019787//small conjugating protein ligase activity;GO:0032559;GO:0019787//small conjugating protein ligase activity;GO:0032559 GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0010993//regulation of ubiquitin homeostasis;GO:0000087//M phase of mitotic cell cycle;GO:0051443//positive regulation of ubiquitin-protein ligase activity;GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0010993//regulation of ubiquitin homeostasis;GO:0000087//M phase of mitotic cell cycle;GO:0051443//positive regulation of ubiquitin-protein ligase activity 5740122 2556.00 0.075 0.09 0.263034405833794 Up 0.0530973451327434 CG34334 CG34334 K09564|1|1e-08|62.4|aga:AgaP_AGAP009810|peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8];K12897|3|6e-08|60.1|xla:444408|transformer-2 protein - GO:0005488//binding - 14462649 904.00 0.765 1.015 0.407948074492524 Up 0.143739268260468 12798097 1117.00 2.72 1.76 -0.628031222613042 Down 0.309734513274336 39064 1355.00 13.385 11.265 -0.24876982540535 Down 0.346321489895654 PGRP-LF peptidoglycan recognition protein LF K01446|1|0.0|770|dme:Dmel_CG4437|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response 41404 2946.00 5.165 5.745 0.153538543781054 Up 0.175868445383701 CG18476 CG18476 K09228|1|3e-177|622|dpo:Dpse_GA11270|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 43068 1450.00 27.105 23.415 -0.211125968886691 Down 0.371087042662792 CHKov2 CHKov2 - - - - 39868 605.23 17.545 35.225 1.00553975879483 Up 0.694426099590543 CG13026 CG13026, isoform C - - - - 5740101 1172.55 1.15 0.71 -0.695742931439693 Down 0.212224276845859 CG34459 CG34459, isoform C - - - - 35498 773.42 19.77 3.215 -2.62042222840126 Down 0.762679963016775 TpnC4 troponin C isoform 4, isoform B K02183|1|2e-24|112|dre:368217|calmodulin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 19835397 823.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 39195 3501.88 1.94 2.695 0.474228620565378 Up 0.264925373134328 Gem3 Gemin3, isoform B K13131|1|0.0|1763|dme:Dmel_CG6539|ATP-dependent RNA helicase DDX20 [EC:3.6.4.13] GO:0016604//nuclear body;GO:0030529//ribonucleoprotein complex GO:0042623//ATPase activity, coupled;GO:0004386//helicase activity;GO:0032559 GO:0048741//skeletal muscle fiber development;GO:0022613//ribonucleoprotein complex biogenesis 32906 816.00 0.2 0.395 0.981852653289741 Up 0.147635715229164 HP1D3csd heterochromatin protein 1D3 chromoshadow domain - - - - 39686 7245.66 24.28 28.005 0.205916006691676 Up 0.371681415929204 CG6498 CG6498, isoform B K08789|1|0.0|3047|dme:Dmel_CG6498|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 37715 1499.00 0.08 0.24 1.58496250072116 Up 0.143343019416193 Or59b odorant receptor 59b K08471|1|0.0|781|dme:Dmel_CG3569|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 40544 3871.00 11.4 13.65 0.259867126755111 Up 0.358142913749835 Syt14 synaptotagmin 14, isoform D K01104|1|1e-22|108|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|3|1e-14|82.4|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10];K00923|4|3e-06|54.7|nve:NEMVE_v1g90881|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] - - GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport 35074 2168.00 0.195 0.175 -0.156119201917282 Down 0.0504556861709153 CG5681 CG5681 K10352|1|2e-08|61.2|cbr:CBG21911|myosin heavy chain - - - 39505 2275.00 20.09 18.62 -0.109624491174498 Down 0.220017170783252 flr flare, isoform B K04539|1|4e-16|87.0|aga:AgaP_AGAP010318|guanine nucleotide binding protein (G protein), beta 5;K12662|2|6e-16|86.3|api:100163110|U4/U6 small nuclear ribonucleoprotein PRP4 - GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0006909//phagocytosis;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008154//actin polymerization or depolymerization;GO:0006909//phagocytosis;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008154//actin polymerization or depolymerization 19835922 559.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 318715 1010.00 0.5 0.475 -0.0740005814437769 Down 0.049432043323207 CG31406 CG31406, isoform B - - - - 10178965 395.00 0.01 0.605 5.91886323727459 Up 0.398197067758552 CG42833 CG42833 - - - - 34565 2013.00 4.82 6.45 0.420266014080655 Up 0.366067890635319 mre11 meiotic recombination 11 K10865|1|0.0|1140|dme:Dmel_CG16928|double-strand break repair protein MRE11 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0004518//nuclease activity GO:0006281//DNA repair;GO:0000723//telomere maintenance;GO:0022403;GO:0000077//DNA damage checkpoint 42447 7601.71 9.585 11.635 0.279620873737198 Up 0.358109893012812 Lrrk Leucine-rich repeat kinase, isoform D K08843|1|0.0|808|cel:T27C10.6|leucine-rich repeat kinase 1 [EC:2.7.11.1];K08844|3|5e-60|234|bfo:BRAFLDRAFT_119973|leucine-rich repeat kinase 2 [EC:2.7.11.1] GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding;GO:0004672//protein kinase activity;GO:0032559 GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process 42995 2941.55 28.91 28.35 -0.0282198736474583 Down 0.0988310659093911 CG6422 CG6422, isoform D - - - - 37028 2506.00 72.87 55.695 -0.387777174781125 Down 0.571324791969357 CG5009 CG5009 K00232|1|0.0|1255|dme:Dmel_CG5009|acyl-CoA oxidase [EC:1.3.3.6] - - - 32522 4151.55 26.195 26.39 0.0106998886572088 Up 0.0608572183331132 Graf GRAF ortholog, isoform J K13736|1|5e-131|469|bta:510704|Rho GTPase-activating protein 10 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding GO:0009987//cellular process;GO:0023060;GO:0009987//cellular process;GO:0023060;GO:0009987//cellular process;GO:0023060;GO:0009987//cellular process;GO:0023060;GO:0009987//cellular process;GO:0023060;GO:0009987//cellular process;GO:0023060 12798028 641.00 0.125 0.145 0.214124805352848 Up 0.0516774534407608 50167 491.00 1.17 2.08 0.830074998557688 Up 0.318518029322414 CG14974 CG14974, isoform A - - - - 32896 1319.00 0.115 0.07 -0.716207033999409 Down 0.0690133403777572 tgy twiggy, isoform E K00731|1|2e-78|292|dmo:Dmoj_GI12045|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0016020//membrane GO:0048531//beta-1,3-galactosyltransferase activity GO:0007444//imaginal disc development;GO:0016266//O-glycan processing;GO:0009653//anatomical structure morphogenesis;GO:0006664//glycolipid metabolic process 40031 2002.00 0.06 0.295 2.29768054864069 Up 0.185213313961168 bora aurora borealis - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0045860//positive regulation of protein kinase activity;GO:0007049//cell cycle;GO:0008105//asymmetric protein localization 39465 1637.00 5.89 1.19 -2.30730606052252 Down 0.647272487121913 CG14118 CG14118 - - GO:0043169//cation binding;GO:0003824//catalytic activity - 36642 1581.79 0.41 0.515 0.328948522565135 Up 0.0958591995773346 CG12857 CG12857, isoform B K10475|1|2e-11|70.5|ecb:100064087|kelch repeat and BTB domain-containing protein 8 - GO:0005488//binding - 318158 1026.00 0.125 0.29 1.21412480535285 Up 0.137432307489103 Gr9a gustatory receptor 9a K08471|1|4e-168|590|dme:Dmel_CG32693|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 5740766 2239.00 1.725 2.335 0.43682618804413 Up 0.233720776647735 CG34313 CG34313 K01025|1|0.0|635|dme:Dmel_CG31743| [EC:2.8.2.-];K01017|3|1e-53|211|api:100160220|chondroitin 4-sulfotransferase 11 [EC:2.8.2.5];K07779|4|5e-48|192|rno:500257|chondroitin 4-sulfotransferase 13 [EC:2.8.2.5] GO:0031224//intrinsic to membrane GO:0016782//transferase activity, transferring sulfur-containing groups GO:0005975//carbohydrate metabolic process 38256 1682.00 13.185 14.665 0.153479499892395 Up 0.255844670453044 Mfap1 Microfibril-associated protein 1 K13110|1|3e-143|508|dsi:Dsim_GD13659|microfibrillar-associated protein 1 GO:0005681//spliceosomal complex GO:0005488//binding GO:0000377;GO:0000086//G2/M transition of mitotic cell cycle 38814 1426.00 0.83 0.635 -0.386354744574759 Down 0.128021397437591 CG14834 CG14834 - - - - 36154 1044.00 11.255 11.835 0.0724936492804594 Up 0.135616166952846 CG18004 CG18004, isoform D K11669|1|3e-129|461|dme:Dmel_CG18004|INO80 complex subunit E - - - 35862 746.00 5.045 3.905 -0.369531720964378 Down 0.306465460309074 PGRP-SC2 PGRP-SC2 K01446|1|9e-106|381|dme:Dmel_CG14745|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0002376//immune system process 38227 3165.00 17.015 19.055 0.16336245684716 Up 0.287214370624752 CG13933 CG13933, isoform B K10380|1|4e-12|74.3|dse:Dsec_GM23234|ankyrin GO:0005875//microtubule associated complex GO:0003774//motor activity GO:0007017//microtubule-based process 33265 1259.06 41.635 47.765 0.198157040649335 Up 0.38878615770704 kraken kraken, isoform B K01175|1|5e-33|142|mmu:68607| [EC:3.1.-.-];K13703|2|4e-06|52.8|cin:100176416|abhydrolase domain-containing protein 11 - GO:0016787//hydrolase activity GO:0042221//response to chemical stimulus 5740394 1771.00 0.43 0.38 -0.178337241258512 Down 0.0649848104609695 CG34164 CG34164, isoform C K02937|1|1e-143|510|dme:Dmel_CG5317|large subunit ribosomal protein L7e GO:0033279 GO:0005198//structural molecule activity GO:0010467//gene expression 42207 2041.00 0.665 1.135 0.771266051789725 Up 0.226225069343548 CG7669 CG7669 - - - - 40776 1138.00 0.98 0.655 -0.581286842577758 Down 0.173854180425307 Osi19 osiris 19, isoform B - - - - 42266 1870.00 7.015 6.105 -0.200451808632496 Down 0.233621714436666 CG14291 CG14291 K01565|1|0.0|1089|dme:Dmel_CG14291|N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1] - GO:0016788//hydrolase activity, acting on ester bonds - 43703 2244.00 0.205 0.155 -0.403355694231209 Down 0.0730748910315678 CG11340 CG11340 K05195|1|3e-39|163|dre:192124|glycine receptor alpha-3 GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0005237//inhibitory extracellular ligand-gated ion channel activity GO:0006810//transport 8674085 359.00 1.08 1.235 0.193479729421209 Up 0.0990952318055739 Sfp33A1 seminal fluid protein 33A1 - - - - 37059 910.00 4.01 1.86 -1.10829961534689 Down 0.481442345793158 CG10912 CG10912 - - - - 38800 1776.53 44.105 26.715 -0.723292200216398 Down 0.660546823405098 CG14830 CG14830, isoform C - - - - 43597 355.00 13.975 12.845 -0.121641392829736 Down 0.212059173160745 CecA2 cecropin A2 - - - GO:0042742//defense response to bacterium 318627 843.09 2.33 1.705 -0.450558215630108 Down 0.238739928675208 CG31206 CG31206, isoform B - - - - 19835713 412.00 0.33 1.465 2.15036273506379 Up 0.409259014661207 - CG45081, isoform B - - - - 41621 920.00 0.175 0.43 1.29698173775713 Up 0.179665830141329 CG14380 CG14380 - - - - 43235 2449.00 11.63 8.75 -0.410496174753527 Down 0.444492141064589 T48 transcript 48, isoform B - GO:0044459//plasma membrane part - GO:0010004//gastrulation involving germ band extension 32652 1926.01 56.455 56.18 -0.00704473608684816 Down 0.0631686699247127 CG4678 CG4678, isoform L K01296|1|2e-105|383|tgu:100225708|carboxypeptidase M [EC:3.4.17.12] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 34835 3399.21 28.805 33.36 0.211800030965434 Up 0.383073570202087 CG33090 CG33090, isoform E - GO:0031224//intrinsic to membrane GO:0015926//glucosidase activity;GO:0004620//phospholipase activity GO:0006678//glucosylceramide metabolic process;GO:0008202//steroid metabolic process;GO:0016139//glycoside catabolic process 34176 1481.79 14.725 14.07 -0.0656453054812902 Down 0.141361775194822 fu12 fu12, isoform D K13509|1|2e-72|273|cqu:CpipJ_CPIJ004138|lysophosphatidate acyltransferase [EC:2.3.1.51] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process 37936 1001.00 63.9 71.125 0.15454081624695 Up 0.333905692775063 CG42361 CG42361 - - - - 34458 3356.99 8.505 13.515 0.66817837087131 Up 0.561847840443799 CG31872 CG31872, isoform B K01046|1|5e-68|259|dme:Dmel_CG7329|triacylglycerol lipase [EC:3.1.1.3];K01066|3|8e-66|252|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|4|1e-58|229|ssc:100142668|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 19835026 402.00 0.215 0.125 -0.782408564927373 Down 0.0974772156914542 36578 3205.36 54.07 65.235 0.270817853103225 Up 0.475696737551182 opa1-like optic atrophy 1 ortholog, isoform E K01528|1|2e-25|118|cel:C02C6.1|dynamin GTPase [EC:3.6.5.5] - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006944//cellular membrane fusion;GO:0032502//developmental process;GO:0006944//cellular membrane fusion;GO:0032502//developmental process 12798080 989.00 0.86 1.18 0.456378294659743 Up 0.168174613657377 CG43123 CG43123 - - - - 12798459 853.00 0.28 0.77 1.4594316186373 Up 0.259410910051512 CG43331 CG43331 - - - - 35946 1777.00 2.695 0.79 -1.7703607145754 Down 0.492372209747722 Cyp4p2 Cyp4p2 K00517|1|0.0|979|dme:Dmel_CG1944| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 37564 4068.00 3.95 4.77 0.272136612941046 Up 0.240820235107648 rad50 rad50, isoform E K10866|1|0.0|2470|dme:Dmel_CG6339|DNA repair protein RAD50 [EC:3.6.-.-] GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0016788//hydrolase activity, acting on ester bonds;GO:0032559 GO:0006259//DNA metabolic process 41628 2318.00 14.005 12.515 -0.162283692386174 Down 0.263010170387003 CG8449 CG8449 - - - - 34615 1347.59 154.47 142.17 -0.119709609164856 Down 0.295931845198785 Rh5 rhodopsin 5, isoform B K13802|1|1e-51|203|dpe:Dper_GL12414|opsin Rh1 GO:0031224//intrinsic to membrane;GO:0042995//cell projection GO:0004930//G-protein coupled receptor activity GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007602//phototransduction;GO:0016037 34357 2246.00 6.085 5.96 -0.0299449322515668 Down 0.0651829348831066 CG4901 CG4901 K13117|1|5e-122|438|ecb:100055664|ATP-dependent RNA helicase DDX35 [EC:3.6.4.13];K12818|5|3e-120|432|hmg:100204531|ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13] GO:0030529//ribonucleoprotein complex GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000398//mRNA splicing, via spliceosome 42950 2049.65 28.5 29.94 0.0711123021189504 Up 0.172434288733325 CG5805 CG5805, isoform B K05863|1|3e-08|60.8|cbr:CBG03436|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator);K13354|2|7e-08|59.3|bfo:BRAFLDRAFT_125172|solute carrier family 25 member 17;K03454|4|1e-07|58.5|dpo:Dpse_GA20987|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 35166 667.00 0.9 1.185 0.396890152568585 Up 0.155494650640602 robl37BC robl37BC K10419|1|4e-12|70.9|smm:Smp_056780|dynein light chain roadblock-type GO:0005875//microtubule associated complex - GO:0007017//microtubule-based process 40744 1194.00 0.035 0.04 0.192645077942396 Up 0.0382380134724607 Or83c odorant receptor 83c K08471|1|8e-08|58.2|dme:Dmel_CG1854|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 3346205 681.00 1.62 0.755 -1.10144526355955 Down 0.328127063796064 CheB53a chemosensory protein B 53a - GO:0044421//extracellular region part - GO:0009593//detection of chemical stimulus 14462600 492.00 0.42 0.47 0.162271428898877 Up 0.0640932505613525 35266 2012.00 2.65 2.285 -0.213798194392492 Down 0.149947166820763 bsh brain-specific homeobox, isoform C K09361|1|3e-17|90.5|ptr:745472|BarH-like homeobox GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007417//central nervous system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007417//central nervous system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 31587 1410.00 88.645 60.13 -0.559954300016517 Down 0.646711134592524 Spat serine pyruvate aminotransferase K00830|1|2e-104|379|xla:398137|alanine--glyoxylate transaminase / serine--pyruvate aminotransferase [EC:2.6.1.44 2.6.1.51] - - - 39736 1164.74 54.17 32.78 -0.724678236371594 Down 0.669198256505085 CG17032 CG17032, isoform B - - - - 31846 2668.00 8.77 8.64 -0.0215455302812643 Down 0.0624091929731872 dalao dalao K11651|1|2e-179|629|dme:Dmel_CG7055|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1 GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-dependent 45269 1136.01 129.455 82.545 -0.649197953687115 Down 0.67481178179897 Prosbeta5 proteasome beta5 subunit, isoform B K02737|1|1e-147|522|dme:Dmel_CG12323|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0031023//microtubule organizing center organization;GO:0007052//mitotic spindle organization;GO:0006508//proteolysis;GO:0031023//microtubule organizing center organization;GO:0007052//mitotic spindle organization;GO:0006508//proteolysis 318954 1186.00 6.61 0.715 -3.2086351247293 Down 0.705950336811518 CG31809 CG31809, isoform C K10251|1|9e-59|227|mcc:714962|beta-keto reductase [EC:1.1.1.-];K00100|2|9e-51|200|dme:Dmel_CG1444| [EC:1.1.1.-];K00044|3|3e-50|198|cin:445663|estradiol 17beta-dehydrogenase [EC:1.1.1.62] - GO:0016491//oxidoreductase activity GO:0008152//metabolic process;GO:0006909//phagocytosis 36800 2377.00 9.675 6.505 -0.572712604313977 Down 0.490886276581693 Tsf3 transferrin 3 K06569|1|1e-27|125|mdo:100032063|melanoma-associated antigen p97 - GO:0005506//iron ion binding GO:0030005;GO:0051707//response to other organism;GO:0000041//transition metal ion transport 36520 1427.00 0.06 0.39 2.70043971814109 Up 0.230748910315678 CG6220 CG6220 - - - GO:0009887//organ morphogenesis 43390 1214.00 4.33 0.955 -2.18079438669098 Down 0.599788667283054 CG9989 CG9989 - - GO:0043169//cation binding;GO:0003824//catalytic activity - 5740351 135.00 0.425 0.01 -5.4093909361377 Down 0.330372473913618 19835077 1210.00 14.305 13.355 -0.0991395216880729 Down 0.184618940694756 3772453 2071.41 4.755 9.335 0.973204681365638 Up 0.582782987716286 CG9133 CG9133, isoform D - - - - 39936 6542.71 2.86 1.51 -0.921466597453311 Down 0.390767401928411 Cad74A cadherin 74A, isoform C K06813|1|8e-148|526|dre:407978|cadherin 23 GO:0044459//plasma membrane part;GO:0016021//integral to membrane;GO:0042995//cell projection;GO:0044459//plasma membrane part;GO:0016021//integral to membrane;GO:0042995//cell projection GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//cell-cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0016337//cell-cell adhesion;GO:0003006//developmental process involved in reproduction 3772100 3529.85 7.9 8.87 0.167081451236599 Up 0.228239334301942 Pmi Pmi, isoform D K01446|1|1e-10|69.7|tca:658396|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding GO:0000270//peptidoglycan metabolic process;GO:0051234//establishment of localization;GO:0002376//immune system process;GO:0000270//peptidoglycan metabolic process;GO:0051234//establishment of localization;GO:0002376//immune system process 31803 3151.80 10.115 11.02 0.123627904012875 Up 0.19577994980848 CG12772 CG12772, isoform B - - - - 43446 1054.74 14.625 11.115 -0.395928676331139 Down 0.466682076343944 CG11882 CG11882, isoform B - - - - 192506 880.74 21.995 18.35 -0.261395538179549 Down 0.405065381059305 CG5986 CG5986, isoform B - - - - 42428 3763.79 76.42 64.245 -0.250366079745313 Down 0.460309074098534 Stat92E Signal-transducer and activator of transcription protein at 92E, isoform M K11224|1|0.0|1292|dme:Dmel_CG4257|signal transducer and activator of transcription 5B;K11223|5|6e-89|329|dre:445474|signal transducer and activator of transcription 5A GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding GO:0006351//transcription, DNA-dependent;GO:0035168//larval lymph gland hemocyte differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0010165//response to X-ray;GO:0007243//intracellular protein kinase cascade;GO:0016055//Wnt receptor signaling pathway;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0019827//stem cell maintenance;GO:0001654//eye development;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006950//response to stress;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation;GO:0006351//transcription, DNA-dependent;GO:0035168//larval lymph gland hemocyte differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0010165//response to X-ray;GO:0007243//intracellular protein kinase cascade;GO:0016055//Wnt receptor signaling pathway;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0019827//stem cell maintenance;GO:0001654//eye development;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006950//response to stress;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation;GO:0006351//transcription, DNA-dependent;GO:0035168//larval lymph gland hemocyte differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0010165//response to X-ray;GO:0007243//intracellular protein kinase cascade;GO:0016055//Wnt receptor signaling pathway;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0019827//stem cell maintenance;GO:0001654//eye development;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006950//response to stress;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation;GO:0006351//transcription, DNA-dependent;GO:0035168//larval lymph gland hemocyte differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0010165//response to X-ray;GO:0007243//intracellular protein kinase cascade;GO:0016055//Wnt receptor signaling pathway;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0019827//stem cell maintenance;GO:0001654//eye development;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006950//response to stress;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation;GO:0006351//transcription, DNA-dependent;GO:0035168//larval lymph gland hemocyte differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0010165//response to X-ray;GO:0007243//intracellular protein kinase cascade;GO:0016055//Wnt receptor signaling pathway;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0019827//stem cell maintenance;GO:0001654//eye development;GO:0000904//cell morphogenesis involved in differentiation;GO:0001709//cell fate determination;GO:0007281//germ cell development;GO:0006950//response to stress;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0007293//germarium-derived egg chamber formation 34548 940.00 6.595 6.84 0.0526236656343529 Up 0.0889578655395588 Csl4 Csl4 K07573|1|7e-113|407|dme:Dmel_CG6249|exosome complex component CSL4 GO:0005694//chromosome;GO:0000178//exosome (RNase complex) GO:0008408//3'-5' exonuclease activity GO:0006396//RNA processing 19835365 1376.00 13.23 10.755 -0.298805536855616 Down 0.390668339717342 35884 918.00 0.425 0.43 0.0168738185643961 Up 0.0413749834896315 CG8252 CG8252 - - - - 40021 1407.00 0.085 0.035 -1.28010791919273 Down 0.0799432043323207 CG7271 CG7271 - GO:0044464//cell part GO:0046914//transition metal ion binding - 40766 1755.00 0.265 0.18 -0.557995453120887 Down 0.0892550521727645 Osi12 osiris 12 K01759|1|5e-29|129|aag:AaeL_AAEL002957|lactoylglutathione lyase [EC:4.4.1.5] - - - 34193 3260.00 133.155 94.715 -0.491441774794452 Down 0.631323471139876 Glt glutactin, isoform D K01063|1|2e-39|164|dme:Dmel_CG8425|juvenile-hormone esterase [EC:3.1.1.59];K03927|2|9e-38|159|api:100168834|carboxylesterase type B [EC:3.1.1.1];K12298|4|1e-35|152|mmu:12613|bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13] GO:0005578//proteinaceous extracellular matrix GO:0046872//metal ion binding - 40409 2110.00 0.555 0.91 0.71337877384859 Up 0.192147668735966 CG11249 CG11249 K00873|1|0.0|1259|dme:Dmel_CG11249|pyruvate kinase [EC:2.7.1.40] - GO:0031420;GO:0016301//kinase activity GO:0006007//glucose catabolic process 37810 2035.00 7.93 7.86 -0.0127915534453719 Down 0.0513802668075551 thoc5 thoc5 K13174|1|0.0|1179|dme:Dmel_CG2980|THO complex subunit 5 - - GO:0006405//RNA export from nucleus 42434 1020.00 14.245 14.48 0.0236059807593541 Up 0.071489895654471 CG5412 CG5412 - - - - 5740259 1081.00 0.04 0.085 1.08746284125034 Up 0.0796790384361379 CG40583 CG40583 K12857|1|2e-09|63.5|aag:AaeL_AAEL007708|Prp8 binding protein;K10266|3|3e-09|62.8|spu:589839|F-box and WD-40 domain protein 10 - GO:0046872//metal ion binding - 36988 943.55 27.055 30.885 0.191011089370959 Up 0.355963545106327 CG14480 CG14480, isoform B - - - - 3771968 25228.53 21.74 25.81 0.24757820106666 Up 0.406287148329151 Msp-300 Muscle-specific protein 300 kDa, isoform M K10382|1|2e-88|331|ecb:100056885|dystonin GO:0031674//I band;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0005887//integral to plasma membrane;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0005887//integral to plasma membrane;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0005887//integral to plasma membrane;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0005887//integral to plasma membrane;GO:0044422;GO:0016021//integral to membrane;GO:0005737//cytoplasm;GO:0043232;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0005887//integral to plasma membrane GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0030528//transcription regulator activity;GO:0008092//cytoskeletal protein binding;GO:0003723//RNA binding;GO:0005099//Ras GTPase activator activity;GO:0008092//cytoskeletal protein binding;GO:0030528//transcription regulator activity;GO:0008092//cytoskeletal protein binding;GO:0003723//RNA binding;GO:0005099//Ras GTPase activator activity GO:0014706//striated muscle tissue development;GO:0051647//nucleus localization;GO:0006139//nucleobase-containing compound metabolic process;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0007300//ovarian nurse cell to oocyte transport;GO:0014706//striated muscle tissue development;GO:0051647//nucleus localization;GO:0006139//nucleobase-containing compound metabolic process;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0007300//ovarian nurse cell to oocyte transport;GO:0014706//striated muscle tissue development;GO:0051647//nucleus localization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0044238//primary metabolic process;GO:0007300//ovarian nurse cell to oocyte transport;GO:0006351//transcription, DNA-dependent;GO:0032318//regulation of Ras GTPase activity;GO:0014706//striated muscle tissue development;GO:0051647//nucleus localization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0007300//ovarian nurse cell to oocyte transport;GO:0009888//tissue development;GO:0051641//cellular localization;GO:0030036//actin cytoskeleton organization;GO:0007300//ovarian nurse cell to oocyte transport;GO:0006351//transcription, DNA-dependent;GO:0032318//regulation of Ras GTPase activity;GO:0014706//striated muscle tissue development;GO:0051647//nucleus localization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0007300//ovarian nurse cell to oocyte transport 37820 1597.00 94.685 102.79 0.118492120596398 Up 0.28985602958658 Gadd34 Gadd34 - - - - 39722 5627.89 34.585 37.075 0.100300236257594 Up 0.231970677585524 Dcp2 decapping protein 2, isoform E K12613|1|0.0|975|dse:Dsec_GM24463|mRNA-decapping enzyme subunit 2 [EC:3.-.-.-] GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0035194//posttranscriptional gene silencing by RNA;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000956//nuclear-transcribed mRNA catabolic process 37277 5422.00 21.355 15.335 -0.477745731375122 Down 0.546063928146876 18w 18 wheeler K06850|1|4e-41|171|tgu:100223926|slit 3 - - - 33064 1490.00 0.13 0.205 0.657112286476992 Up 0.0905428609166557 CG15450 CG15450 K13506|1|3e-85|315|dme:Dmel_CG3209|glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 32753 1643.00 3.765 3.9 0.0508242590776828 Up 0.0730748910315678 CG8173 CG8173 K08865|1|2e-53|210|cfa:477371|PDZ-binding kinase [EC:2.7.12.2] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 35029 2066.00 8.41 6.205 -0.438674590124788 Down 0.414806498481046 ApepP aminopeptidase P, isoform B K01262|1|0.0|1236|dme:Dmel_CG6291|X-Pro aminopeptidase [EC:3.4.11.9] GO:0044444//cytoplasmic part GO:0008238//exopeptidase activity - 34463 2332.00 2.63 1.465 -0.844162134870055 Down 0.359727909126932 CG31871 CG31871 K01066|1|7e-92|338|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01046|2|4e-91|336|dpo:Dpse_GA20265|triacylglycerol lipase [EC:3.1.1.3] - - GO:0044238//primary metabolic process 37871 4816.62 19.305 16.91 -0.191097894531875 Down 0.323900409457139 CG3328 CG3328, isoform C - - GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression 37035 999.00 95.845 93.235 -0.0398315341797444 Down 0.133469819046361 UbcD10 ubiquitin conjugating enzyme 10 K04552|1|3e-87|321|dme:Dmel_CG5788|ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19] - - - 44054 1562.87 50.95 47.515 -0.100699116959647 Down 0.241348566900013 crl courtless, isoform B K04555|1|8e-94|344|dme:Dmel_CG4443|ubiquitin-conjugating enzyme E2 G2 [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0007126//meiosis;GO:0048232//male gamete generation;GO:0007619//courtship behavior 35037 3454.77 12.455 11.905 -0.0651574009705026 Down 0.133469819046361 beat-IIIc beat-IIIc, isoform B - GO:0044464//cell part;GO:0044464//cell part - - 43666 514.00 0.805 0.195 -2.04551465925237 Down 0.305177651565183 CG15550 CG15550 - - - - 3772421 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33845 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 39410 4234.73 35.91 35.085 -0.0335312905910745 Down 0.104345528992207 Ncc69 sodium chloride cotransporter 69, isoform G K10951|1|0.0|848|cfa:481490|solute carrier family 12 member 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015296;GO:0005275//amine transmembrane transporter activity;GO:0015296;GO:0005275//amine transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0006865//amino acid transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0006865//amino acid transport;GO:0030001//metal ion transport 39227 761.00 0.06 0.075 0.321928094887363 Up 0.0540219257693832 CG14147 CG14147 - - - - 36002 2939.78 18.315 17.255 -0.0860112272730436 Down 0.182703737947431 sqa spaghetti-squash activator, isoform D K00907|1|0.0|730|dme:Dmel_CG42347|myosin-light-chain kinase [EC:2.7.11.18] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0065008;GO:0006464//cellular protein modification process;GO:0009967//positive regulation of signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0030036//actin cytoskeleton organization;GO:0065008;GO:0006464//cellular protein modification process;GO:0009967//positive regulation of signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0030036//actin cytoskeleton organization 41611 3881.00 11.405 11.845 0.0546117519280937 Up 0.111742174085326 pic piccolo K10610|1|0.0|2214|dme:Dmel_CG7769|DNA damage-binding protein 1 - - - 32515 1462.00 6.245 6.095 -0.0350753509877454 Down 0.0723484348170651 CG11679 CG11679 - - - - 37295 1429.00 3.33 3.305 -0.0108719055635705 Down 0.0432901862369568 CG11788 CG11788 K11271|1|0.0|849|dme:Dmel_CG11788|sister chromatid cohesion protein DCC1 - - - 246451 540.00 1.13 1.18 0.0624640869466536 Up 0.0554748381983886 CG30093 CG30093 K02266|1|6e-51|199|dme:Dmel_CG30093|cytochrome c oxidase subunit VIa [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity - 19835196 1980.00 1.125 1.12 -0.00642626915943315 Down 0.041044776119403 38137 2363.31 31.69 34.94 0.140851948534526 Up 0.295733720776648 Sac1 Sac1, isoform B K01099|1|5e-49|196|bfo:BRAFLDRAFT_62034|phosphatidylinositol-bisphosphatase [EC:3.1.3.36] - - GO:0043409//negative regulation of MAPK cascade;GO:0048598//embryonic morphogenesis;GO:0043409//negative regulation of MAPK cascade;GO:0048598//embryonic morphogenesis 36975 867.00 8.27 7.65 -0.11242758159126 Down 0.163749834896315 Apc10 anaphase promoting complex subunit 10 K03357|1|3e-111|400|dsi:Dsim_GD25470|anaphase-promoting complex subunit 10 - - - 31115 742.00 6.11 7.87 0.365191255688757 Up 0.367950072645621 CG11509 CG11509 - - - - 41221 2299.00 0.25 0.1 -1.32192809488736 Down 0.134130233786818 Spn85F serpin 85F K12602|1|1e-50|201|der:Dere_GG17291|WD repeat-containing protein 61;K13963|2|2e-10|67.8|bfo:BRAFLDRAFT_130749|serpin B - GO:0004866//endopeptidase inhibitor activity - 46156 8542.58 16.555 20.4 0.301302141461859 Up 0.436236956808876 Gug grunge, isoform J K01463|1|0.0|1671|dme:Dmel_CG6964| [EC:3.5.1.-];K05628|4|2e-57|226|bta:535394|arginine-glutamic acid dipeptide (RE) repeats GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0003002//regionalization;GO:0007423//sensory organ development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007478//leg disc morphogenesis;GO:0006350;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009790//embryo development;GO:0003002//regionalization;GO:0007423//sensory organ development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007478//leg disc morphogenesis;GO:0006350;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009790//embryo development;GO:0003002//regionalization;GO:0007423//sensory organ development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007478//leg disc morphogenesis;GO:0006350;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009790//embryo development;GO:0003002//regionalization;GO:0007423//sensory organ development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007478//leg disc morphogenesis;GO:0006350;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009790//embryo development 19835800 552.00 68.23 77 0.1744522295087 Up 0.366133932109365 14462715 505.00 3.82 3.23 -0.242038473341824 Down 0.197959318451988 CG43800 CG43800, isoform B - - - - 31204 12023.00 5.445 5.125 -0.0873800443240986 Down 0.114515915995245 pcx pecanex, isoform F - - - - 34311 3076.00 11.5 11.155 -0.0439433475875971 Down 0.0976753401135913 Etl1 Etl1 homologue K11647|1|2e-85|317|cbr:CBG08287|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.1.-];K11665|4|6e-84|312|smm:Smp_163620|DNA helicase INO80 [EC:3.6.1.-] - GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0032559 - 42719 429.00 1.75 1.535 -0.189116266462149 Down 0.113954563465857 CG13838 CG13838 - - - - 34258 3315.03 5.595 3.545 -0.658352503736878 Down 0.434387795535596 Mco1 multicopper oxidase-1, isoform C K00540|1|3e-25|117|cel:F21D5.3| [EC:1.-.-.-];K03900|3|3e-12|74.7|dpo:Dpse_GA20020|von Willebrand factor;K10955|5|1e-09|66.2|gga:771289|intestinal mucin-2 - GO:0015082;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0015082;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0015082;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 43265 2276.25 13.57 17.005 0.325538285288988 Up 0.440034341566504 gb genderblind, isoform B K03450|1|2e-135|483|dpo:Dpse_GA23621|solute carrier family 7 (L-type amino acid transporter), other;K13780|2|5e-116|419|bta:282369|solute carrier family 7 (L-type amino acid transporter), member 5 GO:0031224//intrinsic to membrane;GO:0045202//synapse GO:0005275//amine transmembrane transporter activity GO:0023061;GO:0015804//neutral amino acid transport;GO:0015718//monocarboxylic acid transport;GO:0015711//organic anion transport;GO:0007619//courtship behavior 42959 2791.00 0.35 0.72 1.04064198449735 Up 0.212092193897768 niki nimA-like kinase K08857|1|0.0|1657|dme:Dmel_CG10951|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] - GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0006464//cellular protein modification process 14462412 1866.00 0.8 1.135 0.504620392403553 Up 0.175868445383701 19835556 427.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 14462903 514.00 2.8 1.955 -0.518258219637614 Down 0.282129177123233 36532 1441.00 162.95 127.355 -0.355573750661457 Down 0.572150310394928 CG6357 CG6357 K01371|1|7e-07|55.5|tca:660669|cathepsin K [EC:3.4.22.38];K01365|2|7e-07|55.5|dya:Dyak_GE12574|cathepsin L [EC:3.4.22.15] - - - 32549 959.00 20.3 23.355 0.202251717727654 Up 0.350383040549465 CG15916 CG15916 - - - GO:0042254//ribosome biogenesis 5740514 152.00 0.36 0.42 0.222392421336448 Up 0.069937921014397 37405 732.00 1.24 1.325 0.0956522390636864 Up 0.0668339717342491 CG9406 CG9406 K12042|1|3e-12|72.0|dre:58082|troponin C, skeletal muscle;K02183|2|8e-12|70.5|cin:445635|calmodulin - - - 36183 450.00 126.37 156.495 0.308462552851662 Up 0.534605732399947 Listericin listericin - - - - 37817 996.56 12.47 12.575 0.0120969348632195 Up 0.0555739004094571 CG10904 CG10904, isoform B - - - - 35929 3254.02 32.87 28.13 -0.224661903765611 Down 0.393871351208559 CG18659 CG18659, isoform I K01289|1|0.0|671|dme:Dmel_CG18659|carboxypeptidase [EC:3.4.16.-] - - - 41295 1528.00 17.985 15.3 -0.233262506555366 Down 0.360223220182274 Art1 arginine methyltransferase 1 K11434|1|0.0|717|dme:Dmel_CG6554|protein arginine N-methyltransferase 1 [EC:2.1.1.-] GO:0044424//intracellular part GO:0016274//protein-arginine N-methyltransferase activity GO:0035247//peptidyl-arginine omega-N-methylation 19835406 600.00 0.14 0.305 1.12338241550528 Up 0.136573768326509 38302 597.66 40.035 41.275 0.044006408937498 Up 0.12650244353454 mRpL23 mitochondrial ribosomal protein L23, isoform D - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 40303 2580.63 48.485 62.375 0.363429426506031 Up 0.549630167745344 CG3618 CG3618, isoform B - - - GO:0065008;GO:0030036//actin cytoskeleton organization;GO:0065008;GO:0030036//actin cytoskeleton organization 47764 1624.23 22.745 5.955 -1.93337602142754 Down 0.738739928675208 Amy-p amylase proximal, isoform B K01176|1|0.0|900|dme:Dmel_CG18730|alpha-amylase [EC:3.2.1.1] - GO:0046872//metal ion binding;GO:0016160//amylase activity GO:0044238//primary metabolic process 32228 1841.23 255.995 154.34 -0.730003621453969 Down 0.699709417514199 ade5 ade5, isoform B K01587|1|0.0|854|dme:Dmel_CG3989|phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6] - GO:0016881//acid-amino acid ligase activity;GO:0016831//carboxy-lyase activity;GO:0032559 GO:0006188//IMP biosynthetic process;GO:0002118//aggressive behavior 32027 1990.50 66.43 64.075 -0.0520733408997741 Down 0.151003830405495 CG2145 CG2145, isoform B K01362|1|5e-42|172|mmu:19011| [EC:3.4.21.-];K08014|2|3e-41|170|gga:426888|Rap guanine nucleotide exchange factor (GEF) 3 - - - 43153 676.00 0.675 0.34 -0.989352755800492 Down 0.198619733192445 E(spl)malpha-BFM enhancer of split malpha, bearded family member - - - GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway 36025 4660.07 23.325 24.24 0.0555126177338299 Up 0.146843217540615 sec24 Sec24AB ortholog, isoform C K14007|1|0.0|1693|dme:Dmel_CG1472|protein transport protein SEC24 GO:0012507//ER to Golgi transport vesicle membrane GO:0046914//transition metal ion binding GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 32126 3208.00 0.73 1.43 0.970046777898372 Up 0.289657905164443 inaF-D inaF-D - GO:0044464//cell part GO:0016247//channel regulator activity;GO:0005488//binding GO:0016057//regulation of membrane potential in photoreceptor cell 37856 2928.62 39.02 16.955 -1.2025029935836 Down 0.716384889710738 CG16786 CG16786, isoform C - - - - 35020 2123.00 6.57 6.4 -0.0378214654349672 Down 0.0758816536785101 CG13283 CG13283 K08635|1|6e-06|53.1|dya:Dyak_GE16732|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34086 1288.33 23.665 29.35 0.310605581259051 Up 0.473517368907674 CG7231 CG7231, isoform F - - - - 3772142 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 32116 1163.46 14 15.97 0.189937485578904 Up 0.307125875049531 CG2371 CG2371, isoform C - - - - 14462489 450.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 CG44174 CG44174 - - - - 46140 2556.00 35.125 44.615 0.345030614573093 Up 0.527968564258354 l(3)02640 lethal (3) 02640 K01749|1|0.0|1225|dme:Dmel_CG9165|hydroxymethylbilane synthase [EC:2.5.1.61] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0006778//porphyrin-containing compound metabolic process;GO:0018065//protein-cofactor linkage;GO:0018130 39349 2618.00 0.205 0.14 -0.550197082560479 Down 0.0792497688548408 byn brachyenteron, isoform C K10172|1|0.0|972|dme:Dmel_CG7260|brachyury protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0048565//digestive tract development;GO:0008354//germ cell migration;GO:0010468//regulation of gene expression;GO:0045165//cell fate commitment;GO:0006351//transcription, DNA-dependent;GO:0001707//mesoderm formation 41018 1404.00 0.09 0.035 -1.36257007938471 Down 0.0864152687887994 Or85e odorant receptor 85e - - - - 2768941 1884.03 14.315 27.585 0.946356310133741 Up 0.672533350944393 CG33296 CG33296, isoform C K05034|1|7e-39|162|tgu:100222137|solute carrier family 6 (neurotransmitter transporter, GABA) member 1;K05042|5|3e-35|150|ecb:100053016|solute carrier family 6 (neurotransmitter transporter, glycine) member 9 GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport 3355181 12632.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 kl-2 male fertility factor kl2 K10408|1|0.0|5837|dme:Dmel_CG17866|dynein heavy chain, axonemal GO:0005856//cytoskeleton GO:0017111//nucleoside-triphosphatase activity - 318085 393.00 6.305 3.755 -0.747683462813948 Down 0.482267864218729 CG32551 CG32551 - - - - 40704 5808.15 36.21 36.595 0.0152583687451439 Up 0.079877162858275 plx pollux, isoform F K11837|1|8e-09|64.3|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K13136|2|2e-07|59.7|nvi:100114269|gem associated protein 8 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005102//receptor binding;GO:0005099//Ras GTPase activator activity;GO:0005102//receptor binding;GO:0005099//Ras GTPase activator activity;GO:0005102//receptor binding GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 43772 2792.58 78.87 82.465 0.0643052943737122 Up 0.174316470743627 CG2316 CG2316, isoform H K05676|1|0.0|1419|dme:Dmel_CG2316|ATP-binding cassette, subfamily D (ALD), member 2 - - - 43798 1573.82 285.88 276.99 -0.0455758009051005 Down 0.159358076872276 CG1970 CG1970, isoform B K03935|1|0.0|949|dme:Dmel_CG1970|NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3] - - - 37233 4742.48 18.345 21.58 0.234307960239474 Up 0.375181614053626 Fak focal adhesion kinase, isoform G K05725|1|0.0|2236|dya:Dyak_GE13847|PTK2 protein tyrosine kinase 2 [EC:2.7.10.2] GO:0043232;GO:0005924//cell-substrate adherens junction GO:0060089;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0065008;GO:0007010//cytoskeleton organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006464//cellular protein modification process 35129 2261.76 37.82 36.36 -0.0567971637556543 Down 0.160315678245938 Faf Fas-associated factor, isoform B - GO:0044424//intracellular part GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity GO:0016192//vesicle-mediated transport;GO:0007276//gamete generation;GO:0040023//establishment of nucleus localization;GO:0001745//compound eye morphogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0070646//protein modification by small protein removal 33538 1908.00 0.025 0.09 1.84799690655495 Up 0.0883634922731475 CG3347 CG3347, isoform C K13179|1|1e-09|65.1|api:100167834|ATP-dependent RNA helicase DDX18 [EC:3.6.4.13];K11728|2|3e-09|64.3|dme:Dmel_CG32346|nucleosome-remodeling factor subunit BPTF;K11445|3|6e-09|63.2|tad:TRIADDRAFT_19587|JmjC domain-containing histone demethylation protein 1D/E/F - - - 12798365 990.00 1.975 3.61 0.870146183822706 Up 0.41890106987188 CG43439 CG43439 - - - - 33489 2639.00 62.395 61.145 -0.0291958935793932 Down 0.108737287016246 CG31694 CG31694 - - - - 53564 798.00 4255.005 3521.545 -0.272952308906162 Down 0.509047681944261 retinin retinin - - - - 3772449 417.04 2.27 3.79 0.739505550880177 Up 0.396446968696341 CG14245 CG14245, isoform B - - - - 37497 604.00 0.405 0.525 0.374395514781498 Up 0.101241579712059 CG13494 CG13494 - - - - 41270 819.00 3.955 3.915 -0.0146653871817512 Down 0.0472856954167217 Rrp46 Rrp46 K12590|1|1e-130|465|dme:Dmel_CG4043|exosome complex component RRP46 GO:0000178//exosome (RNase complex) GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0010467//gene expression 44544 3145.93 28.065 25.085 -0.161947121197643 Down 0.313069607713644 Hnf4 hepatocyte nuclear factor 4, isoform F K08704|1|0.0|987|dme:Dmel_CG9310|hepatocyte nuclear factor 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0030258//lipid modification;GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0030258//lipid modification;GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0030258//lipid modification;GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0030258//lipid modification 35998 4343.00 62.51 59.425 -0.0730170043490302 Down 0.18940694756307 Uba1 ubiquitin activating enzyme 1, isoform C K03178|1|0.0|2199|dme:Dmel_CG1782|ubiquitin-activating enzyme E1 [EC:6.3.2.19] GO:0043005//neuron projection GO:0019787//small conjugating protein ligase activity;GO:0032559 GO:0032446//protein modification by small protein conjugation;GO:0007420//brain development;GO:0042551//neuron maturation;GO:0010876//lipid localization;GO:0051056//regulation of small GTPase mediated signal transduction 3772272 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 36545 1429.69 88.985 63.685 -0.482608556367483 Down 0.618808611808216 CG13349 regulatory particle non-ATPase 13, isoform G - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0061135;GO:0061135;GO:0061135;GO:0061135;GO:0061135 GO:0043623//cellular protein complex assembly;GO:0043623//cellular protein complex assembly;GO:0043623//cellular protein complex assembly;GO:0043623//cellular protein complex assembly;GO:0043623//cellular protein complex assembly 41419 2063.00 15.53 17.09 0.138094567288838 Up 0.251518953903051 CG14722 CG14722 K13109|1|2e-55|217|ecb:100072389|IK cytokine;K13137|3|2e-12|74.3|tad:TRIADDRAFT_22326|serine-threonine kinase receptor-associated protein;K01062|4|1e-11|72.0|bfo:BRAFLDRAFT_59218|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47];K11802|5|2e-11|71.2|tca:655314|WD repeat-containing protein 32 - - - 41642 643.00 11.235 5.11 -1.13660492824229 Down 0.630134724607053 CheA87a chemosensory protein A 87a - - - - 35996 1347.00 25.53 22.695 -0.169819049469226 Down 0.320169066173557 CG12926 CG12926 K10693|1|1e-13|77.8|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K00683|2|7e-06|52.0|tca:659407|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] GO:0044464//cell part - GO:0051234//establishment of localization 34854 5002.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 CG42685 CG42685 K04988|1|4e-08|61.6|spu:373507|polycystin 1L2 - - - 50463 590.00 0.89 1.225 0.460904508036173 Up 0.170981376304319 CG5693 CG5693 - - - - 36404 1340.00 0.09 0.285 1.66296501272243 Up 0.161471404041738 mos mos K04367|1|2e-22|107|spu:584463|proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0009967//positive regulation of signal transduction 36811 5227.07 0.36 0.885 1.29768054864069 Up 0.262779025227843 CG33017 CG33017, isoform D K13172|1|2e-15|86.3|hmg:100205341|serine/arginine repetitive matrix protein 2;K13106|2|7e-11|70.9|dmo:Dmoj_GI22604|pre-mRNA-splicing factor CWC26;K12811|3|6e-10|67.8|hmg:100202415|ATP-dependent RNA helicase DDX46/PRP5 [EC:3.6.4.13];K09566|5|7e-10|67.4|xtr:407915|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8] - - - 32420 2342.00 3.665 3.81 0.0559777993595101 Up 0.0767401928411042 CG9509 CG9509, isoform B K00108|1|0.0|1264|dme:Dmel_CG9509|choline dehydrogenase [EC:1.1.99.1];K00115|2|6e-92|338|dme:Dmel_CG12398|glucose dehydrogenase (acceptor) [EC:1.1.99.10] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0009888//tissue development;GO:0044281//small molecule metabolic process 33608 2346.00 4.045 3.55 -0.188320678037933 Down 0.173556993792101 slp2 sloppy paired 2 K09385|1|5e-139|495|dme:Dmel_CG2939|forkhead box protein G GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006355//regulation of transcription, DNA-dependent;GO:0048468//cell development;GO:0003002//regionalization;GO:0009790//embryo development;GO:0030182//neuron differentiation 14462664 819.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 31580 2022.00 0.255 0.07 -1.86507041991389 Down 0.154437987055871 swa swallow - - - - 43574 1681.81 24.57 24.865 0.017218573440597 Up 0.0765090476819443 CG7943 CG7943, isoform B K03454|1|3e-09|63.9|cel:C54G10.4|mitochondrial carrier protein, MC family;K08769|2|8e-07|55.8|cfa:403574|mitochondrial brown fat uncoupling protein 1 GO:0031224//intrinsic to membrane;GO:0031967;GO:0031224//intrinsic to membrane;GO:0031967 - GO:0006810//transport;GO:0006810//transport 2768963 394.00 0.755 0.01 -6.23840473932508 Down 0.440727777043984 CG13064 CG13064 - - - - 326144 424.00 0.445 0.245 -0.86102358685119 Down 0.14469686963413 CG31477 CG31477, isoform C K02135|1|2e-30|130|dme:Dmel_CG31477|F-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process;GO:0006950//response to stress;GO:0006818//hydrogen transport;GO:0010259//multicellular organismal aging;GO:0006754//ATP biosynthetic process;GO:0006950//response to stress 59218 2142.62 8.455 9.83 0.217386661930597 Up 0.28648791441025 CG18870 CG18870, isoform B - - - - 34453 3743.88 8.92 10.38 0.218690828437576 Up 0.292332584863294 Trim9 Trim9, isoform B K10649|1|0.0|1305|dme:Dmel_CG31721|tripartite motif-containing protein 9/67 GO:0042995//cell projection;GO:0043232;GO:0030136//clathrin-coated vesicle;GO:0042995//cell projection;GO:0043232;GO:0030136//clathrin-coated vesicle GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0046914//transition metal ion binding;GO:0016874//ligase activity GO:0031333//negative regulation of protein complex assembly;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0031333//negative regulation of protein complex assembly;GO:0017158//regulation of calcium ion-dependent exocytosis 33775 1532.91 12.415 11.3 -0.135761488874291 Down 0.225696737551182 CG6907 CG6907, isoform B K11375|1|0.0|833|dme:Dmel_CG6907|elongator complex protein 4 GO:0043234//protein complex;GO:0044424//intracellular part GO:0019887//protein kinase regulator activity GO:0006355//regulation of transcription, DNA-dependent 19836069 631.00 9.625 9.155 -0.072226654672289 Down 0.126205256901334 19834931 2333.78 27.615 25.43 -0.118920665380956 Down 0.252278430854577 - CG45085, isoform B - - - - 36995 528.47 78.145 82.28 0.0743882265364568 Up 0.19300620789856 CG14483 CG14483, isoform C - - - - 33918 580.84 548.71 534.85 -0.0369095276724031 Down 0.139314489499406 CoVb cytochrome c oxidase subunit Vb, isoform B K02265|1|2e-67|255|dsi:Dsim_GD23418|cytochrome c oxidase subunit Vb [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0022904//respiratory electron transport chain 12798465 867.68 0.155 0.27 0.800691191776594 Up 0.110652489763572 CG43194 CG43194, isoform B - - - - 3772680 537.00 0.23 0.29 0.334419039070559 Up 0.0762118610487386 CG33640 CG33640 - - - - 318790 2158.00 8.255 13.705 0.731362207912517 Up 0.581197992339189 CG31538 CG31538 - - - - 318664 1377.00 3.64 6.245 0.778763121409261 Up 0.488607845727117 CG31288 CG31288 - - - - 19835116 337.00 9.315 5.845 -0.672352744409981 Down 0.515618808611808 32566 2559.45 147.49 154.505 0.0670363852086164 Up 0.197497028133668 eIF5 eIF5, isoform G K03262|1|0.0|790|dme:Dmel_CG9177|translation initiation factor eIF-5 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation 38602 478.00 28.96 39.975 0.465036431284489 Up 0.584830273411703 CG10674 CG10674 - - - - 50202 281.00 0.485 0.01 -5.59991284218713 Down 0.355831462158235 CG15126 CG15126 - - - - 40142 3746.00 0.65 1.1 0.758991900496205 Up 0.219819046361115 CG9392 male sterile (3) 76Cc K13172|1|8e-06|53.5|oaa:100075123|serine/arginine repetitive matrix protein 2 - - - 35306 4207.87 10.92 11 0.0105306674921695 Up 0.0526350548144235 rtGEF Rho-type guanine nucleotide exchange factor, isoform H K13710|1|9e-98|358|gga:418761|Rho guanine nucleotide exchange factor 7 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 19835377 262.00 0.18 0.01 -4.16992500144231 Down 0.1939307885352 40378 2317.55 26.61 24.175 -0.138452620658016 Down 0.281666886804913 Hr78 Hormone-receptor-like in 78, isoform F K14031|1|0.0|935|dme:Dmel_CG7199|nuclear receptor subfamily 2 group C GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0007424//open tracheal system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0007424//open tracheal system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0007424//open tracheal system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0007424//open tracheal system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0007424//open tracheal system development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0007424//open tracheal system development 42045 1216.00 35.95 24.645 -0.54469678965543 Down 0.606062607317395 CG3678 CG3678, isoform B - - - - 32981 1885.13 56.25 48.325 -0.219083363893164 Down 0.418306696605468 Cdc42 Cdc42, isoform D K04393|1|2e-102|372|dme:Dmel_CG12530|cell division control protein 42 GO:0030427//site of polarized growth;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0070161 GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity GO:0006909//phagocytosis;GO:0033674//positive regulation of kinase activity;GO:0009611//response to wounding;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048812//neuron projection morphogenesis;GO:0008154//actin polymerization or depolymerization;GO:0003006//developmental process involved in reproduction;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0007391//dorsal closure;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0051235;GO:0006935//chemotaxis;GO:0007292//female gamete generation;GO:0030010//establishment of cell polarity;GO:0016477//cell migration;GO:0000165//MAPK cascade 53428 1795.44 8.515 8.54 0.00422953994194762 Up 0.0416061286487914 wds will die slowly, isoform B K01062|1|4e-46|186|bfo:BRAFLDRAFT_59218|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47];K13124|3|9e-46|184|tad:TRIADDRAFT_21018|mitogen-activated protein kinase organizer 1 - - - 39282 595.00 0.205 0.305 0.573185332944802 Up 0.09708096684718 Vha16-2 vacuolar H[+] ATPase 16kD subunit 2 K02155|1|3e-73|273|dme:Dmel_CG32089|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] GO:0031224//intrinsic to membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015078//hydrogen ion transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 36966 3639.61 26.89 31.82 0.242864080458175 Up 0.412263901730287 qkr54B quaking related 54B, isoform E K13198|1|1e-39|166|bta:538775|KH domain-containing, RNA-binding, signal transduction-associated protein 1 - - - 39922 3059.70 40.1 44.22 0.141096788473943 Up 0.304913485669 CG6512 CG6512, isoform B K08956|1|0.0|1229|dsi:Dsim_GD12422|AFG3 family protein [EC:3.4.24.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0016462//pyrophosphatase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process 37794 1239.00 12.465 14 0.167543944340828 Up 0.27212389380531 CG5339 CG5339 - - - - 41269 2901.00 54.505 98.135 0.84837918648486 Up 0.703737947430987 Irp-1B iron regulatory protein 1B K01681|1|0.0|1755|dme:Dmel_CG6342|aconitate hydratase 1 [EC:4.2.1.3] - GO:0003729//mRNA binding;GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0016836//hydro-lyase activity GO:0006446//regulation of translational initiation 19834811 349.00 3.73 8.36 1.16432731182564 Up 0.598765024435345 318693 865.00 2.555 4.545 0.830957003256486 Up 0.447695152555805 CG31347 CG31347 - - - - 35718 1362.81 8.435 7.125 -0.243498054348099 Down 0.287940826839255 CG1941 CG1941, isoform D K11172|1|3e-52|206|mcc:694889|diacylglycerol O-acyltransferase 2-like protein 6 [EC:2.3.1.-];K11160|4|1e-49|197|tgu:100220095|diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.76] - GO:0016746//transferase activity, transferring acyl groups - 10178870 2285.00 2.01 2.035 0.0178332930873187 Up 0.046559239202219 CG42727 CG42727 K09228|1|2e-34|147|mcc:713173|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 40093 2184.84 35.605 27 -0.399120445395556 Down 0.545238409721305 nes nessy, isoform C K13515|1|0.0|1005|dme:Dmel_CG9655|lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0007276//gamete generation;GO:0003006//developmental process involved in reproduction;GO:0007276//gamete generation;GO:0003006//developmental process involved in reproduction;GO:0007276//gamete generation;GO:0003006//developmental process involved in reproduction 36782 1682.99 269.465 171.355 -0.653109608674856 Down 0.683595297847048 Got1 glutamate oxaloacetate transaminase 1, isoform B K00813|1|0.0|859|dsi:Dsim_GD11164|aspartate aminotransferase [EC:2.6.1.1] GO:0031980;GO:0031980 GO:0008483//transaminase activity;GO:0048037//cofactor binding;GO:0008483//transaminase activity;GO:0048037//cofactor binding GO:0006536//glutamate metabolic process;GO:0009066//aspartate family amino acid metabolic process;GO:0006536//glutamate metabolic process;GO:0009066//aspartate family amino acid metabolic process 35949 4185.33 149.615 150.84 0.0117642323668554 Up 0.0690133403777572 hig hikaru genki, isoform D K06494|1|4e-29|130|gga:424402|selectin, endothelial cell;K06496|5|1e-28|129|cfa:403994|selectin, platele - - - 38493 2490.82 244.68 248.525 0.0224948036450913 Up 0.0925571258750495 Rop Ras opposite, isoform B K12479|1|3e-28|127|dre:561653|vacuolar protein sorting-associated protein 45 GO:0005624//membrane fraction;GO:0012505//endomembrane system;GO:0033267//axon part;GO:0044444//cytoplasmic part GO:0000149//SNARE binding GO:0051301//cell division;GO:0044087;GO:0048278//vesicle docking;GO:0009314//response to radiation;GO:0016079//synaptic vesicle exocytosis 42210 3018.79 13.25 22.43 0.759437260748348 Up 0.631620657773082 gl glass, isoform C K09214|1|0.0|756|dme:Dmel_CG7672|glass;K09228|2|3e-35|150|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein - - - 46020 5617.13 106.36 93.02 -0.193342837333056 Down 0.400970809668472 NAT1 NAT1, isoform D K03260|1|0.0|2285|dme:Dmel_CG3845|translation initiation factor eIF-4F - GO:0008135//translation factor activity, nucleic acid binding;GO:0034212//peptide N-acetyltransferase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0034212//peptide N-acetyltransferase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0034212//peptide N-acetyltransferase activity GO:0044260;GO:0048102//autophagic cell death;GO:0044260;GO:0048102//autophagic cell death;GO:0044260;GO:0048102//autophagic cell death 37101 281.00 233.705 130.74 -0.837987997892344 Down 0.713313961167613 CG18107 CG18107 - - - - 35504 1060.00 36.99 28.68 -0.367090276422091 Down 0.531204596486594 kune kune-kune - GO:0031224//intrinsic to membrane - - 317943 1358.63 1.245 1.38 0.148522524710088 Up 0.0881983885880333 CG32260 CG32260, isoform C K01316|1|3e-41|169|gga:427967|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462483 504.00 0.165 0.275 0.736965594166206 Up 0.105369171839915 CG44158 CG44158 - - - - 34597 1814.00 4.23 2.29 -0.885310065023006 Down 0.450138687095496 Mal-B1 maltase B1 K01187|1|0.0|1209|dme:Dmel_CG14934|alpha-glucosidase [EC:3.2.1.20] - GO:0015926//glucosidase activity;GO:0043167//ion binding GO:0044238//primary metabolic process 35768 3773.76 91.79 108.46 0.24075418159691 Up 0.459120327565711 CG14762 CG14762, isoform B K06260|1|3e-26|121|gga:768872|platelet glycoprotein V;K13023|2|8e-25|116|mcc:707574|carboxypeptidase N regulatory subunit GO:0044464//cell part GO:0046914//transition metal ion binding - 35800 2036.00 0.08 0.93 3.53915881110803 Up 0.391824065513142 dpn deadpan K09090|1|0.0|707|dme:Dmel_CG8704|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0040029//regulation of gene expression, epigenetic;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction 246527 1139.34 0.9 0.835 -0.108148803855622 Down 0.0625082551842557 CG30284 CG30284, isoform B - - - - 36006 2376.69 19.94 9 -1.14766850318116 Down 0.677717606656981 CG1698 CG1698, isoform B K05336|1|0.0|1220|dme:Dmel_CG1698|solute carrier family 6 (neurotransmitter transporter), invertebrate GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport;GO:0007610//behavior 42232 3231.45 6.045 2.94 -1.03992618441276 Down 0.537709681680095 CG14304 CG14304, isoform C - - GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding GO:0006022;GO:0006022 42516 1090.00 24.875 26.42 0.0869339409284543 Up 0.199544313829085 CG5862 CG5862 - - - - 50133 593.99 173.055 130.03 -0.412386110772636 Down 0.600217936864351 CG13551 CG13551, isoform B - - - GO:0042742//defense response to bacterium;GO:0042742//defense response to bacterium 40367 956.00 0.085 0.365 2.10236171762968 Up 0.20192180689473 sa spermatocyte arrest - GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0044430//cytoskeletal part;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex;GO:0000794//condensed nuclear chromosome - GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0007140//male meiosis 31411 1392.00 0.93 1.43 0.620712525670358 Up 0.222989037115308 CG2871 CG2871 K12850|1|5e-07|55.8|mmu:66921|pre-mRNA-splicing factor 38B;K10384|2|3e-06|53.1|hsa:388698|filaggrin - - - 36859 1664.00 9.885 13.59 0.459232585038183 Up 0.489598467837802 CG5089 CG5089 - - - - 36075 6058.82 5.285 6.625 0.326016982955241 Up 0.321621978602562 CG12912 CG12912, isoform B - - - - 34349 1389.00 0.03 0.105 1.8073549220576 Up 0.10183595297847 CG13137 CG13137 - - - - 12798158 640.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 CG43438 CG43438 - - - - 37531 1663.00 3.595 2.87 -0.32494103376361 Down 0.241183463214899 CG3045 CG3045 K01718|1|0.0|984|dme:Dmel_CG3045|pseudouridylate synthase [EC:4.2.1.70];K01855|2|0.0|771|dpo:Dpse_GA15853| [EC:5.4.99.-] - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0009451//RNA modification;GO:0006399//tRNA metabolic process 42493 2039.00 5.615 5.815 0.0504931690726172 Up 0.0838726720380399 r-l rudimentary-like K13421|1|0.0|874|dme:Dmel_CG3593|uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] GO:0015630//microtubule cytoskeleton GO:0016763//transferase activity, transferring pentosyl groups;GO:0016831//carboxy-lyase activity GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0006222//UMP biosynthetic process 19836202 476.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 37885 1167.38 0.39 0.625 0.680382065799839 Up 0.150772685246335 CG13577 CG13577, isoform C - - - - 32415 2034.00 11.945 9.245 -0.369661629052136 Down 0.426627922335227 CG9519 CG9519 K00108|1|0.0|1250|dme:Dmel_CG9519|choline dehydrogenase [EC:1.1.99.1];K00115|4|1e-133|477|dme:Dmel_CG12539|glucose dehydrogenase (acceptor) [EC:1.1.99.10] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 31037 4192.72 27.45 34.55 0.33187956138306 Up 0.501320829480914 CG3711 CG3711, isoform E K01787|1|2e-15|85.5|mcc:698140|N-acylglucosamine 2-epimerase [EC:5.1.3.8];K10317|5|3e-15|85.1|ame:413363|F-box protein 42 - - - 33653 993.41 91.615 99.48 0.118822679386117 Up 0.289360718531238 Gs1l GS1-like, isoform B - - GO:0005488//binding;GO:0005488//binding - 37481 1221.49 41.545 40.48 -0.0374655670052005 Down 0.124091929731872 HmgD high mobility group protein D, isoform D K09272|1|2e-13|76.6|dgr:Dgri_GH21151|structure-specific recognition protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding GO:0051276//chromosome organization;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0051276//chromosome organization;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0051276//chromosome organization;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 3355151 1848.28 41.93 40.26 -0.0586356579250498 Down 0.163188482366926 scro scarecrow, isoform F K09344|1|1e-31|137|xla:398187|homeobox protein Nkx-2.4;K09342|2|3e-31|137|gga:395322|homeobox protein Nkx-2.1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 38721 5439.34 21.775 24.195 0.152036220390572 Up 0.291110817593449 Trn transportin, isoform D - GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016020//membrane GO:0008565//protein transporter activity;GO:0005488//binding;GO:0008565//protein transporter activity;GO:0005488//binding;GO:0008565//protein transporter activity;GO:0005488//binding GO:0007411//axon guidance;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0015031//protein transport;GO:0035146;GO:0007411//axon guidance;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0015031//protein transport;GO:0035146;GO:0007411//axon guidance;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0015031//protein transport;GO:0035146 37493 1182.00 0.1 0.365 1.86789646399265 Up 0.188911636507727 PpN58A protein phosphatase N at 58A K01090|1|2e-172|605|dme:Dmel_CG3245|protein phosphatase [EC:3.1.3.16];K06269|2|1e-112|406|dre:327301|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] GO:0031981//nuclear lumen;GO:0008287//protein serine/threonine phosphatase complex;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding GO:0005980//glycogen catabolic process;GO:0006412//translation;GO:0001763//morphogenesis of a branching structure;GO:0005978//glycogen biosynthetic process;GO:0007126//meiosis;GO:0030323//respiratory tube development;GO:0006464//cellular protein modification process;GO:0048646//anatomical structure formation involved in morphogenesis 42318 1536.00 0.445 0.305 -0.544996093403511 Down 0.112699775458988 CG3734 CG3734, isoform B K01285|1|1e-67|257|dme:Dmel_CG11626|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2];K09649|2|4e-48|192|mmu:54373|protease, serine, 16 (thymus) [EC:3.4.-.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 14462725 509.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 246413 584.00 5.825 0.545 -3.41792991476472 Down 0.698685774666491 Cpr49Aa cuticular protein 49Aa - - GO:0005198//structural molecule activity - 36563 1990.13 7.535 9.1 0.272259033488235 Up 0.31904636111478 CG8257 CG8257, isoform B K01883|1|0.0|1134|dme:Dmel_CG8257|cysteinyl-tRNA synthetase [EC:6.1.1.16] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 38876 2757.00 4.165 3.27 -0.349025859867465 Down 0.271463479064853 CG32365 CG32365, isoform B - - - - 12798021 599.00 0.37 0.08 -2.20945336562895 Down 0.206511689340906 31527 1109.00 4.4 4.865 0.144936281256452 Up 0.155032360322282 CG6041 CG6041 K01362|1|8e-39|160|dme:Dmel_CG14780| [EC:3.4.21.-];K01312|3|1e-35|150|dme:Dmel_CG12386|trypsin [EC:3.4.21.4] - - - 39305 1308.00 10.75 14.94 0.474843488312415 Up 0.506042794875182 CG6083 CG6083 K00011|1|0.0|671|dme:Dmel_CG6083|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity GO:0008152//metabolic process 43872 9522.69 12.88 19.455 0.595008386858239 Up 0.579745079910184 Ppn papilin, isoform G K08621|1|1e-100|370|spu:594564|a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0030247//polysaccharide binding;GO:0004866//endopeptidase inhibitor activity;GO:0005198//structural molecule activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0030247//polysaccharide binding;GO:0004866//endopeptidase inhibitor activity;GO:0005198//structural molecule activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004866//endopeptidase inhibitor activity;GO:0005198//structural molecule activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0030247//polysaccharide binding;GO:0004866//endopeptidase inhibitor activity;GO:0005198//structural molecule activity GO:0043062//extracellular structure organization;GO:0006022;GO:0043062//extracellular structure organization;GO:0006022;GO:0043062//extracellular structure organization;GO:0043062//extracellular structure organization;GO:0006022 35940 2353.28 158.96 168.625 0.0851546654733224 Up 0.238971073834368 ltd lightoid, isoform J K07918|1|0.0|691|dsi:Dsim_GD10095|Ras-related protein Rab-32 - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction;GO:0008306//associative learning;GO:0006810//transport;GO:0048753//pigment granule organization;GO:0035556//intracellular signal transduction;GO:0008306//associative learning;GO:0006810//transport;GO:0048753//pigment granule organization;GO:0035556//intracellular signal transduction;GO:0008306//associative learning;GO:0006810//transport;GO:0048753//pigment granule organization;GO:0035556//intracellular signal transduction;GO:0008306//associative learning;GO:0006810//transport;GO:0048753//pigment granule organization;GO:0035556//intracellular signal transduction;GO:0008306//associative learning;GO:0006810//transport;GO:0048753//pigment granule organization 50437 646.00 4.19 5.445 0.377981805017555 Up 0.322348434817065 CG18662 CG18662 K01112|1|2e-11|68.9|gga:424401| [EC:3.1.3.-] - - - 34747 699.53 211.325 227.82 0.108430954874633 Up 0.281699907541936 CG9306 CG9306, isoform B K03965|1|3e-84|311|dme:Dmel_CG9306|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 9 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0022904//respiratory electron transport chain 40958 2906.49 18.44 19.31 0.0665095085213127 Up 0.153711530841368 puc puckered, isoform B K04459|1|0.0|712|dme:Dmel_CG7850|dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] GO:0043231//intracellular membrane-bounded organelle GO:0008138//protein tyrosine/serine/threonine phosphatase activity GO:0040003//chitin-based cuticle development;GO:0009611//response to wounding;GO:0043409//negative regulation of MAPK cascade;GO:0065008;GO:0007389//pattern specification process;GO:0010259//multicellular organismal aging;GO:0006796//phosphate-containing compound metabolic process;GO:0007297//ovarian follicle cell migration;GO:0030036//actin cytoskeleton organization;GO:0007391//dorsal closure;GO:0001654//eye development;GO:0006915//apoptotic process;GO:0006464//cellular protein modification process;GO:0007560//imaginal disc morphogenesis;GO:0007399//nervous system development;GO:0001738//morphogenesis of a polarized epithelium;GO:0000086//G2/M transition of mitotic cell cycle 43661 1601.00 5.535 2.055 -1.42944492309987 Down 0.575914674415533 CG15547 CG15547 K00940|1|2e-164|578|dme:Dmel_CG15547|nucleoside-diphosphate kinase [EC:2.7.4.6] - GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559 GO:0009209;GO:0009206 32987 3228.00 55.6 63.345 0.188145864911589 Up 0.386738872011623 Bap adaptor protein complex 1/2, beta subunit K12392|1|0.0|1587|dme:Dmel_CG12532|AP-1 complex subunit beta-1 GO:0030119//AP-type membrane coat adaptor complex;GO:0030130//clathrin coat of trans-Golgi network vesicle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0022892;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006901//vesicle coating;GO:0048333//mesodermal cell differentiation;GO:0007517//muscle organ development;GO:0001708//cell fate specification;GO:0015031//protein transport;GO:0048565//digestive tract development;GO:0001505//regulation of neurotransmitter levels 317923 758.00 54.23 45.165 -0.263885961569375 Down 0.459285431250825 Csas CMP-sialic acid synthase K00983|1|1e-105|382|dme:Dmel_CG32220|N-acylneuraminate cytidylyltransferase [EC:2.7.7.43] - GO:0070567 GO:0009226//nucleotide-sugar biosynthetic process;GO:0008610//lipid biosynthetic process 10178875 791.00 0.25 0.115 -1.12029423371771 Down 0.122308809932638 CG42752 CG42752 - - - - 36728 533.87 15.195 13.685 -0.151001240157338 Down 0.257198520670981 CG8204 CG8204, isoform B - - - - 38164 1647.00 1.035 1.225 0.243150981503246 Up 0.111114780081891 FucTD FucTD K07632|1|2e-12|74.3|xtr:447974|galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-];K09669|3|9e-12|72.0|tgu:100226632|alpha-1,3-fucosyltransferase 10 [EC:2.4.1.-];K07633|5|3e-11|70.1|bta:338077|galactoside alpha-1,3-fucosyltransferase 5 [EC:2.4.1.65] GO:0000139//Golgi membrane;GO:0031224//intrinsic to membrane GO:0008417//fucosyltransferase activity GO:0006464//cellular protein modification process 34987 6517.41 16.18 16.49 0.0273797910074898 Up 0.0874389116365077 CG42389 CG42389, isoform H K06252|1|2e-34|149|bfo:BRAFLDRAFT_124749|tenascin - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 326265 825.00 0.05 0.07 0.485426827170242 Up 0.0549134856690001 CG33160 CG33160 K01312|1|2e-34|145|ecb:100055297|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 45012 2488.74 134.03 97.4 -0.460562278539496 Down 0.620327565711267 Vha68-2 vacuolar H[+] ATPase 68 kDa subunit 2, isoform F K02145|1|0.0|1222|dse:Dsec_GM10085|V-type H+-transporting ATPase subunit A [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport;GO:0015986//ATP synthesis coupled proton transport;GO:0015986//ATP synthesis coupled proton transport 39382 2745.00 3.175 3.205 0.0135677649592129 Up 0.0453704926693964 CG5645 CG5645 - - - - 39453 2096.45 21.93 21.225 -0.0471412582331925 Down 0.127030775326905 CG42709 CG42709, isoform D K08129|1|2e-11|70.9|gga:418566|nyctalopin;K08120|2|2e-10|67.8|oaa:100081885|asporin;K05401|3|3e-10|67.4|mmu:142980|toll-like recepto 3 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 36094 1206.00 0.165 0.33 1 Up 0.135748249900938 Gr47a gustatory receptor 47a K08471|1|0.0|673|dme:Dmel_CG12906|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 41239 1002.00 19.645 21.24 0.112621598345467 Up 0.224342887333245 CG6208 gamma soluble NSF attachment protein 2 - GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0015031//protein transport 42661 1203.00 16.98 16.415 -0.048821708980058 Down 0.120426627922335 CSN6 COP9 complex homolog subunit 6 K12179|1|0.0|644|dme:Dmel_CG6932|COP9 signalosome complex subunit 6 - - GO:0031647//regulation of protein stability 34680 3300.55 2.05 1.78 -0.203746668539048 Down 0.127757231541408 CG5776 CG5776, isoform B K13525|1|1e-132|474|spu:585238|transitional endoplasmic reticulum ATPase GO:0043231//intracellular membrane-bounded organelle GO:0016462//pyrophosphatase activity;GO:0032559 - 33440 1484.00 1.575 1.605 0.0272214687350242 Up 0.0473517368907674 Rad1 radiation insensitive 1 K02830|1|5e-149|527|dme:Dmel_CG3240|cell cycle checkpoint protein [EC:3.1.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0003677//DNA binding GO:0006259//DNA metabolic process 44071 6296.00 15.375 14.135 -0.121314527282789 Down 0.219191652357681 Mcr macroglobulin complement-related K06530|1|7e-101|370|bta:534043|CD109 antigen GO:0044421//extracellular region part GO:0043498//cell surface binding;GO:0061135 GO:0006909//phagocytosis;GO:0009620//response to fungus 3772365 382.00 2.385 0.98 -1.2831356118903 Down 0.417349095231806 32377 1757.01 6.74 7.485 0.151253724876558 Up 0.196935675604279 CG1434 CG1434, isoform B K05543|1|0.0|913|dme:Dmel_CG1434|tRNA-dihydrouridine synthase 2 [EC:1.-.-.-] GO:0044464//cell part GO:0030554//adenyl nucleotide binding;GO:0003723//RNA binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0006399//tRNA metabolic process 318213 1910.00 0.71 0.78 0.135655099357566 Up 0.0694756306960771 CG32792 pickpocket 8, isoform H K04832|1|0.0|655|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|2|4e-10|66.6|spu:575477|amiloride-sensitive cation channel 2, neuronal;K04828|5|3e-07|57.4|nve:NEMVE_v1g80340|amiloride-sensitive cation channel 1, neuronal (degenerin) GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0030001//metal ion transport;GO:0030001//metal ion transport 33396 2569.65 16.96 18.58 0.131614331819454 Up 0.245872407872144 CG15385 CG15385, isoform B - - GO:0016791//phosphatase activity - 19835127 2180.00 1.725 0.9 -0.938599455335857 Down 0.312871483291507 - pre-mod(mdg4)-E, isoform B - - - - 39875 1407.91 25.4 26.58 0.0655126076166463 Up 0.165995245013869 CG9705 CG9705, isoform C - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 2768992 478.00 49.15 55.65 0.179190271001379 Up 0.36874257033417 Ilp5 Insulin-like peptide 5 - - GO:0005102//receptor binding - 5740325 6714.10 17.545 23.23 0.404929206406641 Up 0.515090476819443 CG42732 CG42732, isoform O K04946|1|0.0|763|mcc:721830|potassium channel subfamily T member 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005227//calcium activated cation channel activity;GO:0005227//calcium activated cation channel activity;GO:0005227//calcium activated cation channel activity;GO:0005227//calcium activated cation channel activity GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport 43479 770.00 0.465 1.165 1.32502733354625 Up 0.307026812838463 CG7567 CG7567 - - - - 19836233 671.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 34089 658.75 483.635 397.785 -0.281929779341129 Down 0.516741513670585 CG7224 Starvation-upregulated protein, isoform C - - - - 45250 2167.79 39.34 38.415 -0.0343272039599057 Down 0.105501254788007 deltaCOP coat protein (coatomer) delta, isoform B K12393|1|4e-07|57.0|tca:658536|AP-1 complex subunit mu GO:0030119//AP-type membrane coat adaptor complex;GO:0030120//vesicle coat;GO:0030119//AP-type membrane coat adaptor complex;GO:0030120//vesicle coat GO:0005488//binding;GO:0005488//binding GO:0035151//regulation of tube size, open tracheal system;GO:0006909//phagocytosis;GO:0002168//instar larval development;GO:0019915//lipid storage;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006909//phagocytosis;GO:0002168//instar larval development;GO:0019915//lipid storage;GO:0015031//protein transport 45234 1667.65 2629.435 3070.485 0.22371372157781 Up 0.456610751551975 Ggamma30A Ggamma30A, isoform J K04547|1|4e-81|301|dya:Dyak_GE18830|guanine nucleotide binding protein (G protein), gamma 13 GO:0019897//extrinsic to plasma membrane;GO:0042995//cell projection;GO:0044424//intracellular part;GO:0019897//extrinsic to plasma membrane;GO:0042995//cell projection;GO:0044424//intracellular part;GO:0019897//extrinsic to plasma membrane;GO:0042995//cell projection;GO:0044424//intracellular part;GO:0019897//extrinsic to plasma membrane;GO:0042995//cell projection;GO:0044424//intracellular part;GO:0019897//extrinsic to plasma membrane;GO:0042995//cell projection;GO:0044424//intracellular part;GO:0019897//extrinsic to plasma membrane;GO:0042995//cell projection;GO:0044424//intracellular part GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction 43190 2006.45 6.885 6.005 -0.19729240842933 Down 0.229527143045833 tx taxi, isoform B K09104|1|4e-148|525|dme:Dmel_CG5441|bHLH factor, other - GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0061061//muscle structure development;GO:0009888//tissue development 34935 2901.00 0.365 0.46 0.333737397176996 Up 0.0888257825914674 CG7653 CG7653 K11140|1|7e-102|371|dmo:Dmoj_GI22347|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 38293 1079.00 0.11 0.045 -1.28950661719499 Down 0.0926561880861181 CG32302 CG32302 - - GO:0030247//polysaccharide binding GO:0006022 41094 8604.63 28.05 35.045 0.32120785343702 Up 0.494617619865275 pum pumilio, isoform H - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding GO:0048638//regulation of developmental growth;GO:0007267//cell-cell signaling;GO:0008354//germ cell migration;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051726//regulation of cell cycle;GO:0000578//embryonic axis specification;GO:0007281//germ cell development;GO:0051969;GO:0000087//M phase of mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0007267//cell-cell signaling;GO:0008354//germ cell migration;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051726//regulation of cell cycle;GO:0000578//embryonic axis specification;GO:0007281//germ cell development;GO:0051969;GO:0000087//M phase of mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0007267//cell-cell signaling;GO:0008354//germ cell migration;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051726//regulation of cell cycle;GO:0000578//embryonic axis specification;GO:0007281//germ cell development;GO:0051969;GO:0000087//M phase of mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0007267//cell-cell signaling;GO:0008354//germ cell migration;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051726//regulation of cell cycle;GO:0000578//embryonic axis specification;GO:0007281//germ cell development;GO:0051969;GO:0000087//M phase of mitotic cell cycle;GO:0048638//regulation of developmental growth;GO:0007267//cell-cell signaling;GO:0008354//germ cell migration;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051726//regulation of cell cycle;GO:0000578//embryonic axis specification;GO:0007281//germ cell development;GO:0051969;GO:0000087//M phase of mitotic cell cycle 5740362 8293.87 16.765 21.775 0.377220235692442 Up 0.49791969356756 CG34384 CG34384, isoform F K00901|1|0.0|3395|dme:Dmel_CG34384|diacylglycerol kinase [EC:2.7.1.107] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0032559;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0032559 GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0006461//protein complex assembly;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0006461//protein complex assembly 19836170 572.00 0.3 0.4 0.415037499278844 Up 0.0948685774666491 14462594 1433.00 17.18 17.4 0.0183572695976272 Up 0.0708625016510369 44155 1717.00 51.81 41.73 -0.312145662986685 Down 0.506042794875182 Sip1 SRY interacting protein 1 K13358|1|1e-21|105|xtr:100216077|Na(+)/H(+) exchange regulatory cofactor NHE-RF2 GO:0005681//spliceosomal complex;GO:0031012//extracellular matrix GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007635//chemosensory behavior;GO:0000377;GO:0010468//regulation of gene expression 318231 2073.79 5.865 3.34 -0.812283005554456 Down 0.484876502443535 Sdic3 Sperm-specific dynein intermediate chain 3, isoform G K10415|1|0.0|1036|dme:Dmel_CG32823|dynein intermediate chain, cytosolic GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0045502//dynein binding GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport 39143 918.00 627.305 710.945 0.180570892799839 Up 0.403183199049003 ATPsyn-b ATP synthase, subunit b K02127|1|2e-125|448|dme:Dmel_CG8189|F-type H+-transporting ATPase subunit b [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006818//hydrogen transport;GO:0006909//phagocytosis;GO:0006754//ATP biosynthetic process 39666 1007.00 1.115 1.07 -0.059432913519158 Down 0.0554748381983886 ran-like Ran-like K07936|1|2e-123|442|dme:Dmel_CG7815|GTP-binding nuclear protein Ran GO:0043231//intracellular membrane-bounded organelle GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0051169//nuclear transport;GO:0023060;GO:0015031//protein transport 36334 2841.93 7.485 5.105 -0.552091355180615 Down 0.445383700964206 CG30046 CG30046, isoform C K12484|1|2e-15|84.7|dsi:Dsim_GD15625|Rab11 family-interacting protein 1/2/5;K04659|2|9e-09|62.8|cin:619278|thrombospondin;K04596|3|2e-08|61.6|mdo:100032824|brain-specific angiogenesis inhibitor 1 - GO:0004866//endopeptidase inhibitor activity - 43745 1170.00 1.43 0.9 -0.668018240448715 Down 0.231640470215295 CG2150 CG2150 - GO:0005743//mitochondrial inner membrane GO:0015002//heme-copper terminal oxidase activity - 33268 3021.18 32.215 32.325 0.00491777527618557 Up 0.0454695548804649 aru arouser, isoform D - - - GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 19834797 259.00 0.18 0.245 0.444784842672896 Up 0.0830471536124686 43721 1567.00 0.805 0.975 0.276413435634994 Up 0.110091137234183 CG1638 CG1638 K01068|1|4e-07|56.6|nve:NEMVE_v1g115538|palmitoyl-CoA hydrolase [EC:3.1.2.2];K12417|2|2e-06|54.3|cin:100176351|acyl-CoA thioesteraes 11 [EC:3.1.2.-] - - - 31547 3499.93 12.69 13.02 0.0370373793245295 Up 0.0959582617884031 Nep1 neprilysin 1, isoform D K08635|1|0.0|1645|dme:Dmel_CG5905|membrane metallo-endopeptidase-like 1 - - - 14462387 699.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 CG43695 CG43695 - - - - 31089 3556.39 7.65 7.665 0.00282604407876339 Up 0.0401862369568089 CG32813 CG32813, isoform N - - - - 37713 695.00 1.255 1.15 -0.126053503006397 Down 0.0767401928411042 skpF skpF K03094|1|3e-87|320|dme:Dmel_CG12227|S-phase kinase-associated protein 1 GO:0005815//microtubule organizing center;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding GO:0051276//chromosome organization;GO:0019941//modification-dependent protein catabolic process;GO:0006261//DNA-dependent DNA replication;GO:0046605//regulation of centrosome cycle 33025 2336.00 49.43 46.905 -0.0756451864935762 Down 0.201789723946638 Rab10 Rab10 K07976|1|3e-110|399|dya:Dyak_GE17866|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 35091 3786.21 17.28 19.76 0.193479729421209 Up 0.327169462422401 CG7180 CG7180, isoform C K06776|1|8e-93|342|rno:360302|protein tyrosine phosphatase, receptor type, K [EC:3.1.3.48] - GO:0004871//signal transducer activity;GO:0004721//phosphoprotein phosphatase activity;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process 37569 3995.00 17.56 10.12 -0.795083554841048 Down 0.618148197067759 CG4752 CG4752 K01469|1|0.0|2497|dme:Dmel_CG4752|5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9] - GO:0003824//catalytic activity - 31595 2211.00 0.055 0.01 -2.4594316186373 Down 0.0874058908994849 CG14443 CG14443 K12823|1|8e-66|251|dse:Dsec_GM10578|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13];K01509|3|8e-66|251|dpo:Dpse_GA10214|adenosinetriphosphatase [EC:3.6.1.3] - - - 36914 4824.00 10.725 12.41 0.210525467743449 Up 0.302635054814423 Ark Apaf-1-related-killer, isoform B K02084|1|3e-15|83.6|tca:662893|apoptotic protease-activating factor - - - 35005 1662.12 25.7 15.245 -0.753432209071492 Down 0.639611676132611 yellow-b yellow-b, isoform B - - - - 33696 1048.10 9.65 16.025 0.73172350935066 Up 0.596948883899089 CG2837 CG2837, isoform D - - - - 19834793 944.00 0.34 0.245 -0.472752997135131 Down 0.0923259807158896 40788 1587.00 2.495 2.365 -0.0771996319978653 Down 0.0761127988376701 CG42564 CG42564 - - - - 42777 2071.01 1.5 2.055 0.454175893185802 Up 0.222328622374851 CG10164 CG10164, isoform B - - - - 35259 8341.48 37.49 47.685 0.347029691571042 Up 0.531666886804913 Lar Leukocyte-antigen-related-like, isoform I K01104|1|0.0|4055|dme:Dmel_CG10443|protein-tyrosine phosphatase [EC:3.1.3.48];K06777|2|0.0|1259|oaa:100075182|protein tyrosine phosphatase, receptor type, D [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0004871//signal transducer activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004871//signal transducer activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 32217 5080.38 93.975 114.745 0.288082374359545 Up 0.511161009113723 tomosyn tomosyn ortholog, isoform L K08518|1|0.0|1373|dme:Dmel_CG17762|syntaxin binding protein 5 (tomosyn) GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle - GO:0016079//synaptic vesicle exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0016079//synaptic vesicle exocytosis 31460 521.00 63.255 44.825 -0.496875939244552 Down 0.615638621054022 CG16756 CG16756 K01185|1|4e-83|306|dme:Dmel_CG16756|lysozyme [EC:3.2.1.17];K13915|5|8e-21|99.4|cqu:CpipJ_CPIJ005450|lysozyme C [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds - 50048 345.34 25.28 28.35 0.165352271652488 Up 0.325023114515916 CG15922 CG15922, isoform B - - - - 35626 1633.01 0.715 0.92 0.363690619278623 Up 0.126634526482631 Tsp42Ep tetraspanin 42Ep, isoform B K06497|1|2e-07|56.2|nve:NEMVE_v1g236446|CD63 antigen GO:0031224//intrinsic to membrane - - 318031 933.58 12.505 17.355 0.472846307647676 Up 0.521859727909127 CG32442 CG32442, isoform C - - - - 35432 747.00 0.11 0.24 1.12553088208386 Up 0.122407872143706 CG1421 CG1421 - - - - 246428 610.00 10.915 5.435 -1.00596018996348 Down 0.61052040681548 CG30062 CG30062 K01185|1|1e-104|378|dme:Dmel_CG30062|lysozyme [EC:3.2.1.17];K13915|2|8e-33|139|dwi:Dwil_GK12154|lysozyme C [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 19835871 1007.00 0.405 0.32 -0.339850002884625 Down 0.089155989961696 42178 2609.00 11.935 15.5 0.377069649079824 Up 0.463346981904636 CG7985 CG7985, isoform B K04678|1|4e-70|266|tca:661188|E3 ubiquitin ligase SMURF1/2 [EC:6.3.2.19] - - - 33643 867.00 24.55 25.74 0.0682890290186464 Up 0.166490556069211 CG3652 CG3652 - GO:0044464//cell part - - 39551 12659.00 12.175 12.325 0.0176658742955692 Up 0.0642253335094439 CG9007 upSET, isoform B K09189|1|3e-21|106|dre:325395|myeloid/lymphoid or mixed-lineage leukemia protein 5 - GO:0005488//binding - 41133 1425.65 41.855 33.785 -0.309017122358991 Down 0.494716682076344 GstZ2 glutathione S transferase Z2, isoform C K01800|1|8e-124|443|dya:Dyak_GE24775|maleylacetoacetate isomerase [EC:5.2.1.2] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016859//cis-trans isomerase activity;GO:0016859//cis-trans isomerase activity;GO:0016859//cis-trans isomerase activity GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process 43146 3013.00 96.875 130.15 0.42597900135515 Up 0.605699379210144 boss bride of sevenless K04623|1|0.0|1581|dme:Dmel_CG8285|bride of sevenless protein GO:0031224//intrinsic to membrane GO:0005102//receptor binding;GO:0004888//transmembrane signaling receptor activity GO:0003002//regionalization;GO:0023060;GO:0009746;GO:0042051//compound eye photoreceptor development;GO:0050953//sensory perception of light stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001752//compound eye photoreceptor fate commitment;GO:0033500//carbohydrate homeostasis 2768973 940.00 0.54 1.015 0.910448415021707 Up 0.233951921806895 Rpn12R regulatory particle non-ATPase 12-related K03031|1|4e-149|527|dme:Dmel_CG11552|26S proteasome regulatory subunit N12 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0007052//mitotic spindle organization 43386 2179.00 6.315 7.87 0.317580901719934 Up 0.33839651301017 CG9986 CG9986 - - - - 37888 2517.38 4.965 5.79 0.221769630460863 Up 0.230121516312244 betaTub60D beta-Tubulin at 60D, isoform B K07375|1|0.0|882|dme:Dmel_CG3401|tubulin beta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0009314//response to radiation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006935//chemotaxis;GO:0043623//cellular protein complex assembly;GO:0007017//microtubule-based process;GO:0048513//organ development;GO:0007610//behavior 37356 3371.25 14.78 11.52 -0.359505552703839 Down 0.445912032756571 sktl skittles, isoform C K00889|1|0.0|1471|dme:Dmel_CG9985|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] - - - 3772082 3997.38 43.045 46.965 0.125740341706581 Up 0.290252278430855 kay kayak, isoform G K09031|1|0.0|776|dme:Dmel_CG33956|fos-like antigen, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0009611//response to wounding;GO:0007444//imaginal disc development;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006350;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0007416//synapse assembly;GO:0000165//MAPK cascade;GO:0006351//transcription, DNA-dependent;GO:0009611//response to wounding;GO:0007444//imaginal disc development;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0007416//synapse assembly;GO:0000165//MAPK cascade;GO:0006351//transcription, DNA-dependent;GO:0009611//response to wounding;GO:0007444//imaginal disc development;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0007416//synapse assembly;GO:0000165//MAPK cascade;GO:0009611//response to wounding;GO:0007444//imaginal disc development;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006350;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0007416//synapse assembly;GO:0000165//MAPK cascade 246539 1002.00 1.175 0.665 -0.82123451106381 Down 0.238244617619865 CG30323 CG30323, isoform C K01362|1|5e-10|65.1|dme:Dmel_CG3795| [EC:3.4.21.-];K01327|2|5e-06|51.6|oaa:791113|leukocyte elastase [EC:3.4.21.37] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41831 2262.00 6.775 6.385 -0.0855343265385103 Down 0.126403381323471 CG6654 CG6654 K09228|1|1e-65|251|api:100159445|KRAB domain-containing zinc finger protein - - - 36144 3220.00 3.59 3.875 0.110212466338549 Up 0.115275392946771 CG12325 CG12325, isoform B K10599|1|8e-20|99.8|tad:TRIADDRAFT_64168|pre-mRNA-processing factor 19 [EC:6.3.2.19];K03130|3|1e-19|99.4|tad:TRIADDRAFT_37330|transcription initiation factor TFIID subunit D4;K12662|5|3e-19|97.8|cqu:CpipJ_CPIJ012025|U4/U6 small nuclear ribonucleoprotein PRP4 - - - 35577 1265.64 172.81 170.76 -0.0172166366838551 Down 0.0911702549200898 Rab2 Rab2, isoform B K07976|1|4e-113|409|dme:Dmel_CG3269|Rab family, other;K07877|3|4e-104|379|tgu:100229693|Ras-related protein Rab-2A;K07878|5|5e-104|379|cel:F53F10.4|Ras-related protein Rab-2B GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0043005//neuron projection;GO:0000323//lytic vacuole;GO:0030139//endocytic vesicle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0032561//guanyl ribonucleotide binding;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032559 GO:0006351//transcription, DNA-dependent;GO:0002164//larval development;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0006911//phagocytosis, engulfment;GO:0051169//nuclear transport;GO:0035556//intracellular signal transduction 246533 1064.00 14.82 16.85 0.185203143763387 Up 0.309602430326245 Ppcdc phosphopantothenoylcysteine decarboxylase, isoform B K01598|1|3e-108|391|dme:Dmel_CG30290|phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] - - - 10178845 839.20 0.21 0.575 1.45317262816561 Up 0.219753004887069 7354410 2260.92 10.745 11.355 0.0796622232791043 Up 0.145654471007793 CG42379 CG42379, isoform B K05284|1|0.0|845|dme:Dmel_CG9865|phosphatidylinositol glycan, class M [EC:2.4.1.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups GO:0006497//protein lipidation;GO:0006497//protein lipidation 39471 2284.00 0.465 1.02 1.13326653086346 Up 0.263505481442346 CG11262 CG11262 - GO:0031224//intrinsic to membrane GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006842//tricarboxylic acid transport 53504 1584.00 0.205 0.565 1.4626269577971 Up 0.22011623299432 Ugt86Dg Ugt86Dg K00699|1|0.0|922|dme:Dmel_CG17200|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 37657 2611.37 2.87 2.1 -0.450661409009565 Down 0.264000792497689 CG30194 CG44252, isoform E K08745|1|0.0|1360|dsi:Dsim_GD11732|solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] GO:0016020//membrane;GO:0016020//membrane GO:0015245//fatty acid transporter activity;GO:0015245//fatty acid transporter activity GO:0015908//fatty acid transport;GO:0015908//fatty acid transport 34538 1173.00 2.825 1.68 -0.74978963452379 Down 0.351175538238013 Ast-CC allatostatin double C, isoform C - - - - 38407 2562.88 45.4 46.15 0.0236383503548592 Up 0.0867784968960507 ZnT63C zinc transporter 63C, isoform G K03295|1|0.0|762|dme:Dmel_CG17723|cation efflux system protein, CDF family GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0030005;GO:0006811//ion transport;GO:0030005;GO:0006811//ion transport;GO:0030005;GO:0006811//ion transport;GO:0030005;GO:0006811//ion transport;GO:0030005;GO:0006811//ion transport 35849 2287.00 9.215 9.81 0.0902689705885255 Up 0.150541540087175 CG14749 CG14749 K06063|1|2e-44|181|rno:299219|SNW domain-containing protein 1 GO:0005635//nuclear envelope - GO:0006406//mRNA export from nucleus 3355127 3131.69 27.375 27.005 -0.0196324164239079 Down 0.0795139347510236 CG17494 CG17494, isoform D K10421|1|2e-07|58.9|hsa:6249|CAP-Gly domain-containing linker protein 1;K12478|2|5e-07|57.4|cin:751565|early endosome antigen 1;K10352|3|1e-06|56.2|dpe:Dper_GL10886|myosin heavy chain - GO:0004672//protein kinase activity;GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0000166//nucleotide binding - 42796 1777.00 0.28 0.17 -0.719892080807265 Down 0.104444591203276 CG31148 CG31148 K01201|1|0.0|1161|dme:Dmel_CG31148|glucosylceramidase [EC:3.2.1.45] GO:0000323//lytic vacuole GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding GO:0006643//membrane lipid metabolic process;GO:0007033//vacuole organization 40823 1060.00 1.365 0.18 -2.92283213947754 Down 0.435741645753533 Ccp84Ac Ccp84Ac - - GO:0042302//structural constituent of cuticle - 43467 2237.25 0.035 0.1 1.51457317282976 Up 0.0866464139479593 CG14506 CG14506, isoform C - - GO:0005488//binding - 19834832 378.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 - CG44869 - - - - 36014 1189.00 19.38 17 -0.189033824390017 Down 0.323537181349888 CG1665 CG1665 K01205|1|3e-35|149|ame:551437|alpha-N-acetylglucosaminidase [EC:3.2.1.50] - GO:0048037//cofactor binding;GO:0046914//transition metal ion binding - 41211 933.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 eloF elongase F K00680|1|8e-146|516|dme:Dmel_CG16905| [EC:2.3.1.-];K10250|4|2e-39|162|dre:334217|elongation of very long chain fatty acids protein 7;K10247|5|2e-38|159|tgu:100225083|elongation of very long chain fatty acids protein 1 GO:0031224//intrinsic to membrane GO:0004312//fatty acid synthase activity GO:0019748//secondary metabolic process;GO:0007617//mating behavior 12798494 897.00 13.11 7.595 -0.787545815719671 Down 0.589222031435742 318206 6547.46 19.98 22.47 0.169443541387489 Up 0.311187425703342 tlk Tousled-like kinase, isoform N K08864|1|0.0|732|ame:551673|tousled-like kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response;GO:0000278//mitotic cell cycle;GO:0065008;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0006959//humoral immune response 42933 1442.00 14.72 13.755 -0.0978215317408024 Down 0.18524633469819 Syx18 syntaxin 18 K08492|1|0.0|633|dme:Dmel_CG13626|syntaxin 18 GO:0045202//synapse;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005515//protein binding GO:0006810//transport;GO:0048741//skeletal muscle fiber development;GO:0001505//regulation of neurotransmitter levels 318990 758.25 15.445 17.095 0.146434551805757 Up 0.263406419231277 Qtzl quetzalcoatl, isoform C K04487|1|1e-45|182|dme:Dmel_CG12264|cysteine desulfurase [EC:2.8.1.7];K11462|3|1e-43|176|dya:Dyak_GE18559|polycomb protein EED GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0016783//sulfurtransferase activity;GO:0016846//carbon-sulfur lyase activity;GO:0048037//cofactor binding;GO:0008276//protein methyltransferase activity GO:0034968//histone lysine methylation;GO:0000096//sulfur amino acid metabolic process;GO:0031163;GO:0006522//alanine metabolic process 41914 2433.00 3.61 2.435 -0.568077064804829 Down 0.337570994584599 CG4576 CG4576 K00680|1|1e-16|88.6|dme:Dmel_CG33337| [EC:2.3.1.-] - - - 32613 7992.17 12.67 15.515 0.29224717238791 Up 0.401234975564655 hang hangover, isoform D K10498|1|7e-12|74.7|gga:418400|zinc finger and BTB domain-containing protein 11;K09229|2|4e-10|68.9|ecb:100066288|KRAB and SCAN domains-containing zinc finger protein;K10512|3|2e-08|63.5|rno:362635|zinc finger and BTB domain-containing protein 40;K09228|5|3e-08|62.4|hsa:90592|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006950//response to stress;GO:0030534//adult behavior;GO:0010033//response to organic substance;GO:0006950//response to stress;GO:0030534//adult behavior;GO:0010033//response to organic substance;GO:0006950//response to stress;GO:0030534//adult behavior;GO:0010033//response to organic substance 32589 4100.70 27.1 25.925 -0.0639488625406461 Down 0.154801215163122 CG3632 CG3632, isoform J K01104|1|0.0|877|aag:AaeL_AAEL000564|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 19835497 601.00 0.21 0.51 1.28010791919274 Up 0.195185576542068 42468 2723.00 7.295 5.68 -0.361017048413209 Down 0.353850217936864 CG15695 CG15695 - - - - 32660 3556.73 22.585 18.42 -0.29409185234618 Down 0.436732267864219 CG9634 CG9634, isoform C K01415|1|1e-29|132|ecb:100059042|endothelin-converting enzyme [EC:3.4.24.71] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32275 4685.55 10.47 11.155 0.0914290713133323 Up 0.159424118346322 mew multiple edematous wings, isoform F K06583|1|2e-91|338|hsa:3679|integrin alpha 7;K06482|3|8e-89|329|mmu:16400|integrin alpha 3 GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0007166//cell surface receptor signaling pathway;GO:0007424//open tracheal system development;GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0007439//ectodermal digestive tract development;GO:0010669//epithelial structure maintenance;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006935//chemotaxis;GO:0007431//salivary gland development;GO:0007606//sensory perception of chemical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007424//open tracheal system development;GO:0007409//axonogenesis;GO:0016337//cell-cell adhesion;GO:0048870//cell motility;GO:0007439//ectodermal digestive tract development;GO:0010669//epithelial structure maintenance;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0031589//cell-substrate adhesion;GO:0006935//chemotaxis;GO:0007431//salivary gland development;GO:0007606//sensory perception of chemical stimulus 33165 6476.00 17.805 22.05 0.30849622008182 Up 0.450270770043587 Zir Zizimin-related K05727|1|2e-10|70.1|ecb:100061408|dedicator of cytokinesis 3/4/5 - GO:0046872//metal ion binding;GO:0032561//guanyl ribonucleotide binding;GO:0030695//GTPase regulator activity;GO:0019899//enzyme binding - 19835629 462.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 34109 6465.74 26.765 29.43 0.136939889625401 Up 0.287049266939638 CG8552 CG8552, isoform E K13619|1|4e-40|168|cin:100180467|phospholipase DDHD1 [EC:3.1.1.-] - GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding - 43283 1885.04 6.585 5.195 -0.342059691352303 Down 0.328787478536521 pll pelle, isoform B K08286|1|0.0|934|dme:Dmel_CG5974|protein-serine/threonine kinase [EC:2.7.11.-];K04730|2|1e-38|161|dre:569226|interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] GO:0044424//intracellular part;GO:0016020//membrane GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0032559 GO:0023060;GO:0006508//proteolysis;GO:0006605//protein targeting;GO:0048534;GO:0009798//axis specification;GO:0007166//cell surface receptor signaling pathway;GO:0050832//defense response to fungus;GO:0006464//cellular protein modification process 40403 4880.80 9.985 10.61 0.0875903234707923 Up 0.152720908730683 MED1 mediator complex subunit 1, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0045449;GO:0006351//transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 8674026 6221.65 5.165 5.15 -0.00419591679447877 Down 0.0401862369568089 Gyc76C guanylyl cyclase at 76C, isoform D K12323|1|0.0|781|phu:Phum_PHUM100000|atrial natriuretic peptide receptor A [EC:4.6.1.2];K01769|2|0.0|763|tca:657050|guanylate cyclase, other [EC:4.6.1.2] - GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559 GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0009124//nucleoside monophosphate biosynthetic process 34679 1680.00 2.77 3.67 0.405894086794024 Up 0.279355435213314 CG17036 CG17036, isoform B - GO:0044464//cell part GO:0015291//secondary active transmembrane transporter activity;GO:0016597//amino acid binding GO:0051234//establishment of localization 12798329 656.00 0.915 0.755 -0.277295098958963 Down 0.107416457535332 CG43108 CG43108 - - - - 318011 1254.00 0.01 0.04 2 Up 0.0694426099590543 Or65a odorant receptor 65a K08471|1|5e-43|175|dme:Dmel_CG13206|gustatory receptor;K00254|3|1e-08|61.2|ame:410603|dihydroorotate dehydrogenase [EC:1.3.5.2] GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 8673995 223.66 4.45 4.86 0.127150977752021 Up 0.144069475630696 Sfp70A4 seminal fluid protein 70A4, isoform B - - - - 36207 611.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 Obp47b Odorant-binding protein 47b - - GO:0005488//binding GO:0051234//establishment of localization 19835690 704.00 7.6 9.91 0.38288563885554 Up 0.408763703605865 10178906 408.00 0.315 0.35 0.15200309344505 Up 0.0552767137762515 CG42693 CG42693 - - - - 40071 674.00 2.21 1.48 -0.578449193762482 Down 0.268689737154933 CG14075 CG14075 - - - - 40908 1958.00 16.665 9.2 -0.857115551165873 Down 0.624290054154009 alpha-Est2 alpha-Esterase-2, isoform B K01044|1|0.0|1167|dme:Dmel_CG2505|carboxylesterase [EC:3.1.1.1];K03927|4|0.0|698|dse:Dsec_GM10467|carboxylesterase type B [EC:3.1.1.1];K01066|5|2e-160|565|dpo:Dpse_GA10843|esterase / lipase [EC:3.1.1.-] GO:0044444//cytoplasmic part GO:0004091//carboxylesterase activity - 3355006 1184.00 0.68 1.075 0.660730008339121 Up 0.199346189406948 CG15831 CG15831 K12559|1|6e-75|281|dre:555290|myosin X GO:0015629//actin cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 31220 1875.61 16.77 13.31 -0.333372117652455 Down 0.441024963677189 Ilp6 Insulin-like peptide 6, isoform D - - GO:0005102//receptor binding;GO:0005102//receptor binding GO:0035264//multicellular organism growth;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035264//multicellular organism growth;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 3772496 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33880 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 34489 442.00 21.595 25.41 0.234699058846333 Up 0.388026680755514 CG17127 CG17127, isoform B - - - - 32721 3382.40 61.975 59.4 -0.0612234352859566 Down 0.170816272619205 Fim fimbrin, isoform D K10382|1|8e-15|83.2|ecb:100056885|dystonin - GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0007143//female meiosis;GO:0007143//female meiosis;GO:0007143//female meiosis 40371 2624.35 3.855 3.85 -0.00187241433277057 Down 0.0382380134724607 CG5664 CG5664, isoform B K13093|1|0.0|745|dsi:Dsim_GD12119|HIV Tat-specific factor 1 - GO:0005488//binding - 43120 1041.00 0.15 0.975 2.70043971814109 Up 0.365539558842953 CG14354 CG14354 - - - - 32436 1855.00 5.565 5.195 -0.0992579384377474 Down 0.126469422797517 dob doppelganger von brummer K13534|1|4e-51|202|mmu:116939|patatin-like phospholipase domain-containing protein 3 [EC:3.1.1.3 2.3.1.-] - GO:0004091//carboxylesterase activity GO:0048878//chemical homeostasis;GO:0010259//multicellular organismal aging;GO:0006641//triglyceride metabolic process;GO:0010883//regulation of lipid storage 318160 872.00 17.465 32.865 0.912085342316514 Up 0.677552502971866 CG32706 CG32706 - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0000380//alternative mRNA splicing, via spliceosome 34842 3266.94 9.13 8.42 -0.116794626917826 Down 0.17864218729362 spel1 spellchecker1, isoform F K08735|1|0.0|1663|dya:Dyak_GE19033|DNA mismatch repair protein MSH2 GO:0032300//mismatch repair complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032300//mismatch repair complex GO:0032404;GO:0046872//metal ion binding;GO:0032356;GO:0019900//kinase binding;GO:0032139//dinucleotide insertion or deletion binding;GO:0032559;GO:0032138//single base insertion or deletion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0042802//identical protein binding;GO:0000217//DNA secondary structure binding;GO:0032559;GO:0003690//double-stranded DNA binding GO:0006281//DNA repair;GO:0000018//regulation of DNA recombination;GO:0016445//somatic diversification of immunoglobulins;GO:0051095;GO:0051726//regulation of cell cycle;GO:0007127//meiosis I;GO:0022414//reproductive process;GO:0048523//negative regulation of cellular process;GO:0051276//chromosome organization;GO:0006281//DNA repair 3772376 3702.48 325.91 321.38 -0.0201934688774529 Down 0.0927882710342095 40238 659.00 0.16 0.01 -4 Down 0.178939373926826 CG6434 CG6434 - - - - 31187 6348.12 10.1 11.095 0.135554374557854 Up 0.21582353718135 wapl wings apart-like, isoform C - - - - 31659 3927.00 3.755 3.595 -0.0628211370749741 Down 0.0790186236956809 fz4 frizzled 4, isoform B K02354|1|1e-84|315|bfo:BRAFLDRAFT_269437|frizzled 4 - - - 35753 1589.64 6.85 6.105 -0.166112692860486 Down 0.204002113327169 CG2906 CG2906, isoform E - - GO:0043169//cation binding GO:0044238//primary metabolic process 31912 2934.00 0.47 0.325 -0.532221038649183 Down 0.11260071324792 btd buttonhead K09200|1|3e-150|533|dme:Dmel_CG12653|transcription factor Sp, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010004//gastrulation involving germ band extension;GO:0035287//head segmentation;GO:0007379//segment specification;GO:0006950//response to stress 40187 1026.27 193.905 196.49 0.0191058860174336 Up 0.0918636903975697 CG7646 CG7646, isoform C K08328|1|7e-17|86.7|oaa:100077076|guanylate cyclase activator 1 - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0016491//oxidoreductase activity - 38528 2100.82 43.745 48.96 0.162485429941242 Up 0.337339849425439 Hexo1 hexosaminidase 1, isoform F K12373|1|0.0|1224|dme:Dmel_CG1318|beta-hexosaminidase [EC:3.2.1.52] GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0043167//ion binding;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0043167//ion binding;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0043167//ion binding;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0043167//ion binding;GO:0004563//beta-N-acetylhexosaminidase activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 38543 2197.97 200.01 182.26 -0.13407416034647 Down 0.317989697530049 DOR DOR, isoform H - - - - 31853 869.00 0.055 0.17 1.62803122261304 Up 0.1232664113063 CG12115 CG12115 - - - - 14462345 1001.00 0.87 0.69 -0.334419039070559 Down 0.118676528860124 14462446 1602.00 0.05 0.055 0.137503523749935 Up 0.0448421608770308 41105 1405.82 1.99 2.665 0.421367102215527 Up 0.244419495443138 sage salivary gland-expressed bHLH, isoform C K09081|1|1e-07|57.0|cfa:481516|neurogenin 1;K09073|2|1e-07|56.6|rno:117034|pancreas-specific transcription factor 1a GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter 35284 3204.68 6.84 8.475 0.309217043137808 Up 0.340906089023907 CG43861 CG43861, isoform D - - - - 2768988 767.00 0.925 0.575 -0.685891409571937 Down 0.186765288601242 CG33285 CG33285 - - - - 37924 2351.00 2.83 2.81 -0.0102319226109565 Down 0.0432901862369568 uri unconventional prefoldin RPB5 interactor - GO:0043234//protein complex;GO:0005694//chromosome GO:0005515//protein binding;GO:0004857//enzyme inhibitor activity GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation 5740634 795.00 0.155 0.39 1.33120590847537 Up 0.172467309470347 CG34181 CG34181 - - - - 32540 1598.68 25.685 24.21 -0.0853229943480227 Down 0.197728173292828 CG8578 CG8578, isoform C - - - - 38055 2160.52 5.015 5.33 0.0878858321469952 Up 0.114515915995245 Atac3 Ada2a-containing complex component 3, isoform E K09454|1|0.0|1101|dme:Dmel_CG32343|GA-binding protein transcription factor, beta - GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 14462536 1336.00 0.17 0.14 -0.280107919192735 Down 0.0592061814819707 40725 1627.86 7.85 7.855 0.000918621515207129 Up 0.0401862369568089 dgrn degringolade, isoform D K03175|1|1e-09|65.1|dre:554561|TNF receptor-associated factor 6 - GO:0046872//metal ion binding;GO:0046914//transition metal ion binding - 35261 863.86 13.165 13.32 0.0168865610251995 Up 0.0657773081495179 Nf-YB nuclear factor Y-box B, isoform B K08065|1|8e-64|243|dpo:Dpse_GA10323|nuclear transcription factor Y, beta GO:0005667//transcription factor complex GO:0003677//DNA binding GO:0010467//gene expression 32632 1406.00 72.72 36.115 -1.00975402915295 Down 0.718498216880201 CG9782 CG9782 - - - - 38063 4033.42 7.66 8.925 0.220507776991505 Up 0.277638356888126 CG1233 CG1233, isoform B K09228|1|6e-28|127|ecb:100062031|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 40504 413.57 21.245 12.295 -0.789051608717204 Down 0.632908466516973 CG33169 CG33169, isoform C - - - - 34571 1876.00 11.415 11.375 -0.00506431425128054 Down 0.0472856954167217 CG6488 CG6488 - - - - 34685 1925.73 32.545 26.99 -0.270010937422044 Down 0.44323735305772 CG5792 Pih1D1, isoform D - - - - 31243 1027.00 86.6 85.915 -0.0114569897886128 Down 0.0678906353189803 CG8636 CG8636 K03248|1|2e-149|528|dme:Dmel_CG8636|translation initiation factor eIF-3 subunit 4 - - - 12798005 644.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 39575 1259.12 5.615 8.005 0.511615380115656 Up 0.439010698718795 CG7906 CG7906, isoform B - - - - 41556 1379.00 0.475 0.495 0.0595010117486617 Up 0.0455355963545106 CG11608 CG11608 K01046|1|8e-66|251|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|5|2e-57|223|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - - - 31666 1418.00 14.22 15.28 0.103723078416334 Up 0.191520274732532 Atg5 Autophagy-specific gene 5 K08339|1|5e-159|560|dme:Dmel_CG1643|autophagy-related protein 5 - - - 19835206 422.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 32246 2582.36 3.37 4.22 0.324494407525327 Up 0.259443930788535 hec hector, isoform B K04577|1|2e-77|290|aag:AaeL_AAEL010043|calcitonin receptor-like GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 50380 436.00 1.785 1.035 -0.786293306529774 Down 0.289261656320169 CG15579 CG15579, isoform B - - - - 34514 1625.37 89.995 78.385 -0.199267247396678 Down 0.40929203539823 CG33129 CG33129, isoform H - - - - 33590 423.00 4.24 6.995 0.722259792601554 Up 0.489598467837802 CG3513 CG3513 K06238|1|5e-10|62.8|oaa:100083924|collagen, type VI, alpha - GO:0004866//endopeptidase inhibitor activity - 32052 723.32 33.675 31.415 -0.100224365603561 Down 0.228074230616827 CG15202 CG15202, isoform B - - - - 32428 5605.46 8.75 33.415 1.93314095212947 Up 0.754589882446176 eag ether a go-go, isoform G K05322|1|0.0|1693|der:Dere_GG17855|potassium voltage-gated channel Eag-related subfamily H, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005267//potassium channel activity;GO:0004673//protein histidine kinase activity;GO:0060089;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0004673//protein histidine kinase activity;GO:0060089;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0004673//protein histidine kinase activity;GO:0060089;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0004673//protein histidine kinase activity;GO:0060089;GO:0005244//voltage-gated ion channel activity GO:0006351//transcription, DNA-dependent;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0044057;GO:0042065;GO:0023060;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0006351//transcription, DNA-dependent;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0044057;GO:0042065;GO:0023060;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0006351//transcription, DNA-dependent;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0044057;GO:0042065;GO:0023060;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0006351//transcription, DNA-dependent;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0044057;GO:0042065;GO:0023060;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior 33899 3368.30 58.26 54.48 -0.0967789981282771 Down 0.243527935543521 retm real-time, isoform C - GO:0043231//intracellular membrane-bounded organelle - - 19835386 1766.00 32.3 16.63 -0.957745996294018 Down 0.682670717210408 43278 2066.00 1.245 0.965 -0.367544894800001 Down 0.151135913353586 DNApol-alpha73 DNA polymerase alpha 73kD K02321|1|0.0|1198|dme:Dmel_CG5923|DNA polymerase alpha subunit B - GO:0003676//nucleic acid binding;GO:0034061 GO:0006259//DNA metabolic process 31568 2809.00 2.78 3.11 0.161829697407095 Up 0.135781270637961 CG15896 CG15896, isoform B - - - - 8674010 966.00 0.325 1.39 2.09657325969505 Up 0.39747061154405 CG42623 CG42623 K10359|1|9e-12|70.9|cel:T10H10.1|myosin VII GO:0016459//myosin complex GO:0005515//protein binding;GO:0000166//nucleotide binding - 33685 2218.73 38.335 48.38 0.335748589474204 Up 0.526053361511029 CG12194 CG12194, isoform C - - - GO:0006810//transport;GO:0006810//transport 34377 3430.10 16.44 18.155 0.143156631118525 Up 0.258981640470215 Utx Utx, isoform E K11447|1|0.0|2166|dme:Dmel_CG5640|histone demethylase [EC:1.14.11.-] GO:0005700//polytene chromosome;GO:0005700//polytene chromosome;GO:0005700//polytene chromosome;GO:0005700//polytene chromosome GO:0032451//demethylase activity;GO:0032451//demethylase activity;GO:0032451//demethylase activity;GO:0032451//demethylase activity - 36509 1394.00 0.4 0.165 -1.27753397552891 Down 0.171212521463479 link link - - - - 35058 3302.34 1.505 1.505 -1.60171325190746e-16 Down 0.0382380134724607 qua quail, isoform C K08017|1|1e-71|271|mdo:100015634|advillin;K05761|3|2e-70|267|gga:396423|villin 1 - GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding GO:0007015//actin filament organization;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007015//actin filament organization;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007300//ovarian nurse cell to oocyte transport 38059 4000.52 37.88 42.22 0.156490247878771 Up 0.330438515387663 Ptpmeg ptpmeg, isoform K K01104|1|0.0|1768|dme:Dmel_CG1228|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043232;GO:0044425//membrane part;GO:0043232;GO:0044425//membrane part;GO:0043232;GO:0044425//membrane part;GO:0043232;GO:0044425//membrane part;GO:0043232;GO:0044425//membrane part GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0048675//axon extension;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process;GO:0048675//axon extension;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process;GO:0048675//axon extension;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process;GO:0048675//axon extension;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process;GO:0048675//axon extension;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0048102//autophagic cell death;GO:0006464//cellular protein modification process 34642 4518.45 34.47 37.8 0.133044935741165 Up 0.284803856822084 CG31760 CG31760, isoform D K08469|1|4e-48|194|bfo:BRAFLDRAFT_66969|G protein-coupled receptor 158 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0015075//ion transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity GO:0006811//ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0006811//ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 19836258 745.00 6.035 8.125 0.429014042048158 Up 0.404702152952054 39079 3453.00 15.545 13.725 -0.179644467448503 Down 0.293422269185048 CG4080 CG4080, isoform B K10656|1|0.0|1090|dme:Dmel_CG4080|E3 ubiquitin-protein ligase MARCH1/8 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 42376 2194.00 29.74 28.685 -0.05210812940045 Down 0.138224805177652 CG4462 CG4462 K08209|1|3e-22|107|gga:420423|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13;K08202|3|1e-21|105|dvi:Dvir_GJ24209|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - GO:0006810//transport 34351 1259.00 8.72 9.85 0.175795589566812 Up 0.248051776515652 Ripalpha RPA-interacting protein alpha - - - - 34719 3184.00 18.1 18.58 0.0377608044120849 Up 0.106855105005944 CG9426 CG9426 K13956|1|0.0|1170|dme:Dmel_CG9426|actin-binding protein IPP - GO:0008092//cytoskeletal protein binding GO:0042992//negative regulation of transcription factor import into nucleus 38521 573.97 158.84 194.69 0.293604517821692 Up 0.519284110421345 VhaM9.7-a vacuolar H[+] ATPase M9.7 subunit a, isoform C K02153|1|4e-47|187|dme:Dmel_CG1268|V-type H+-transporting ATPase subunit H [EC:3.6.3.14] GO:0033176;GO:0033176 GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient 33515 1253.00 1.6 1.46 -0.132103536007345 Down 0.0871087042662792 CG17219 CG17219 - - - - 42475 2869.00 121.615 117.435 -0.0504587324893225 Down 0.155725795799762 CG10830 CG10830 - GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005267//potassium channel activity GO:0030001//metal ion transport 40100 1536.00 0.46 1.265 1.4594316186373 Up 0.332353718134989 CG14086 CG14086 - - - - 41175 1903.14 5.155 6.625 0.361948026969815 Up 0.340608902390701 CG9444 CG9444, isoform B K03305|1|6e-67|255|nvi:100119964|proton-dependent oligopeptide transporter, POT family GO:0031224//intrinsic to membrane - GO:0015833//peptide transport 33451 757.00 1.3 1.625 0.321928094887363 Up 0.16114119667151 Prosbeta4R2 proteasome beta4 subunit-related 2, isoform B K02734|1|2e-118|426|dme:Dmel_CG17302|20S proteasome subunit beta 4 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process 36456 1200.75 38.08 25.68 -0.56838827618564 Down 0.617553823801347 AQP aquaporin, isoform B K09884|1|1e-139|496|dme:Dmel_CG12251|aquaporin rerated protein, invertebrate GO:0044464//cell part;GO:0044464//cell part GO:0022891//substrate-specific transmembrane transporter activity;GO:0022891//substrate-specific transmembrane transporter activity GO:0051234//establishment of localization;GO:0051234//establishment of localization 43397 940.00 0.58 0.785 0.436639753764055 Up 0.133403777572315 CG12558 intrepid K01312|1|5e-07|55.1|dpo:Dpse_GA11574|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40055 5316.00 12.43 13.92 0.163332914796243 Up 0.263010170387003 Ugt UDP-glucose-glycoprotein glucosyltransferase K11718|1|0.0|2902|dme:Dmel_CG6850|UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-] GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum GO:0035251//UDP-glucosyltransferase activity GO:0006464//cellular protein modification process 44889 5955.68 6.485 7.295 0.169801403666191 Up 0.212092193897768 ph-d polyhomeotic distal, isoform B K11456|1|0.0|739|dme:Dmel_CG3895|polyhomeotic-like protein 1 GO:0031981//nuclear lumen;GO:0031519//PcG protein complex;GO:0031981//nuclear lumen;GO:0031519//PcG protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0016458//gene silencing;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0002165//instar larval or pupal development;GO:0021953//central nervous system neuron differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007293//germarium-derived egg chamber formation;GO:0016458//gene silencing;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0002165//instar larval or pupal development;GO:0021953//central nervous system neuron differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007293//germarium-derived egg chamber formation 31822 517.00 0.085 0.095 0.160464672193246 Up 0.045238409721305 CG12661 CG12661, isoform B - - - - 34928 1608.05 30.175 29.25 -0.0449171462842545 Down 0.121186104873861 CG3793 CG3793, isoform B K00599|1|4e-61|235|mcc:702050| [EC:2.1.1.-];K00933|4|2e-42|174|mmu:329504|creatine kinase [EC:2.7.3.2] - GO:0016741 - 34587 2786.83 0.295 0.44 0.576788569275456 Up 0.117157574957073 Vha100-5 vacuolar H[+] ATPase 100kD subunit 5, isoform B K02154|1|0.0|1546|dme:Dmel_CG12602|V-type H+-transporting ATPase subunit I [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process 32320 4477.00 9.975 10.195 0.0314730289068883 Up 0.0779949808479725 CG2691 CG2691, isoform B - - - - 19835286 302.00 0.15 0.17 0.180572245641821 Up 0.0511161009113723 38400 1629.17 85.255 43.98 -0.954936843007552 Down 0.713181878219522 CG17746 CG17746, isoform B K01090|1|0.0|710|dme:Dmel_CG17746|protein phosphatase [EC:3.1.3.16] GO:0043234//protein complex;GO:0043234//protein complex GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 40848 1752.00 778.375 752.605 -0.048572499988751 Down 0.162164839519218 alphaTub84B alpha-Tubulin at 84B K07374|1|0.0|859|dvi:Dvir_GJ24568|tubulin alpha GO:0031224//intrinsic to membrane;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0015405;GO:0005198//structural molecule activity;GO:0032559 GO:0006810//transport;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0043623//cellular protein complex assembly;GO:0006959//humoral immune response;GO:0007017//microtubule-based process 37774 1212.00 34.6 32.92 -0.0718077021024609 Down 0.176826046757364 usnp Synaptosomal-associated protein 29kDa K08509|1|2e-145|514|dme:Dmel_CG11173|synaptosomal-associated protein, 29kDa GO:0005624//membrane fraction GO:0005515//protein binding GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport 35686 3152.00 0.505 0.52 0.0422282353892975 Up 0.0449742438251222 Orc1 origin recognition complex subunit 1 K02603|1|0.0|1691|dme:Dmel_CG10667|origin recognition complex subunit 1 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0016458//gene silencing;GO:0006260//DNA replication;GO:0071897//DNA biosynthetic process 39058 983.00 0.435 0.705 0.696607856550065 Up 0.162528067626469 CG4477 CG4477 K01362|1|2e-28|126|dme:Dmel_CG3795| [EC:3.4.21.-];K09639|4|8e-17|87.8|mdo:100018588|transmembrane protease, serine 8 [EC:3.4.21.-];K09629|5|3e-16|85.9|hsa:260429|protease, serine, 33 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37013 1043.00 1.63 1.28 -0.348728154231078 Down 0.168405758816537 CG10934 CG10934 - - - - 3772409 1023.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 His1:CG33864 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 326170 2439.31 8.765 6.915 -0.342024839609044 Down 0.367685906749439 CG31886 CG31886, isoform C K03257|1|1e-45|184|tca:659090|translation initiation factor eIF-4A - - - 34742 4010.82 24.74 28.2 0.188849662309786 Up 0.349887729494122 CG9395 CG9395, isoform D - - - - 19836025 419.00 0.835 1.305 0.644201704095833 Up 0.216715097080967 43699 1075.00 5.68 6.515 0.197874249063453 Up 0.225861841236296 CG1750 CG1750 K00604|1|0.0|687|dme:Dmel_CG1750|methionyl-tRNA formyltransferase [EC:2.1.2.9] - GO:0016742//hydroxymethyl-, formyl- and related transferase activity GO:0010467//gene expression 44554 1762.00 10.465 11.48 0.133550330419979 Up 0.212323339056928 Bzd buzidau K11426|1|0.0|925|dme:Dmel_CG13761|SET and MYND domain-containing protein - GO:0008135//translation factor activity, nucleic acid binding;GO:0046914//transition metal ion binding - 5740572 2333.00 0.18 0.335 0.89616418901546 Up 0.125875049531106 CG34193 CG34193, isoform B - - GO:0016787//hydrolase activity;GO:0005488//binding - 32024 9737.23 12.49 15.185 0.281873431559503 Up 0.390106987187954 CG43901 CG43901, isoform C - - - - 32834 822.00 0.145 0.11 -0.398549376490275 Down 0.0673292827895919 CG15044 CG15044 - - - - 32241 1696.00 44.12 39.4 -0.163237161247644 Down 0.333608506141857 CG4404 CG4404 - - - - 2768918 1229.00 0.035 0.265 2.9205655325056 Up 0.191520274732532 Cpr31A cuticular protein 31A - - GO:0005198//structural molecule activity - 41031 814.60 6.045 7.335 0.279054626424266 Up 0.301116100911372 CG11755 CG11755, isoform B - - - - 31736 2683.00 3.3 3.945 0.257559275767643 Up 0.212224276845859 CG10958 CG10958 - - - - 39833 2822.00 14.88 10.105 -0.558305204728296 Down 0.540351340641923 aos argos K02104|1|0.0|829|dme:Dmel_CG4531|giant-lens protein precursor (argos protein) - - - 33139 5111.54 7.88 7.955 0.0136663008746718 Up 0.0526350548144235 S6kII ribosomal protein S6 kinase II, isoform B K04373|1|0.0|1550|dme:Dmel_CG17596|p90 ribosomal S6 kinase [EC:2.7.11.1] GO:0031224//intrinsic to membrane;GO:0030529//ribonucleoprotein complex;GO:0045202//synapse GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior;GO:0045665//negative regulation of neuron differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0007612//learning;GO:0009996//negative regulation of cell fate specification;GO:0010259//multicellular organismal aging;GO:0023014//signal transduction by phosphorylation;GO:0003002//regionalization;GO:0006464//cellular protein modification process;GO:0006606//protein import into nucleus 41179 3679.00 30.99 30.83 -0.00746786547904072 Down 0.0592722229560164 trbd trabid K11862|1|0.0|1390|dme:Dmel_CG9448|ubiquitin thioesterase ZRANB1 [EC:3.1.2.-] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//small conjugating protein ligase activity GO:0016055//Wnt receptor signaling pathway 34609 1148.00 0.04 0.05 0.321928094887362 Up 0.047219653942676 zuc zucchini K11805|1|4e-12|72.4|dpe:Dper_GL13429|WD repeat-containing protein 68 GO:0043232 - GO:0051276//chromosome organization;GO:0007292//female gamete generation;GO:0003006//developmental process involved in reproduction;GO:0016458//gene silencing 246572 499.00 0.58 0.925 0.67340046538874 Up 0.185642583542465 CG30369 CG30369 - - - - 31210 1228.97 105.815 78.91 -0.423264108991208 Down 0.596948883899089 CG3091 CG3091, isoform C K10693|1|1e-51|204|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K01104|2|2e-06|53.9|dan:Dana_GF22421|protein-tyrosine phosphatase [EC:3.1.3.48] - - - 37471 1235.00 8.795 8.415 -0.0637203061420118 Down 0.111940298507463 NC2alpha negative cofactor 2alpha K08066|1|8e-06|51.6|spu:589551|nuclear transcription factor Y, gamma GO:0017053//transcriptional repressor complex GO:0003677//DNA binding;GO:0016564//transcription repressor activity - 19835848 480.97 8.505 8.52 0.00254219456245347 Up 0.0416061286487914 38487 2820.46 37.315 45.13 0.27433109242679 Up 0.461299696209219 CG14995 CG14995, isoform I K10411|1|2e-07|58.2|tad:TRIADDRAFT_56121|dynein light chain 1, axonemal - - GO:0048102//autophagic cell death;GO:0048102//autophagic cell death;GO:0048102//autophagic cell death;GO:0048102//autophagic cell death;GO:0048102//autophagic cell death;GO:0048102//autophagic cell death 3771992 503.00 16.385 11.94 -0.456572836277955 Down 0.509675075947695 34912 4631.76 10.83 12.535 0.210928753225612 Up 0.303493593977018 kek3 kekkon-3, isoform B K07523|1|0.0|1655|dme:Dmel_CG4192|netrin-G1 ligand - GO:0005488//binding;GO:0005488//binding - 34658 3433.74 28.88 25.565 -0.175900716200228 Down 0.338033284902919 Elf Ef1alpha-like factor, isoform D K03266|1|0.0|978|dme:Dmel_CG6382|peptide chain release factor eRF subunit 2;K03267|2|0.0|669|cfa:479846|G1 to S phase transition protein GO:0044444//cytoplasmic part GO:0032561//guanyl ribonucleotide binding;GO:0008079//translation termination factor activity;GO:0017111//nucleoside-triphosphatase activity GO:0006412//translation 37490 1194.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 CG4372 CG4372 K01444|1|0.0|756|dme:Dmel_CG4372|N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26] - GO:0016787//hydrolase activity - 36131 4886.52 39.9 43.405 0.121472495754704 Up 0.271826707172104 CG33144 CG33144, isoform B K11975|1|0.0|1572|dme:Dmel_CG33144|E3 ubiquitin-protein ligase RNF144 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 39186 1023.98 1.075 1.64 0.609359155028623 Up 0.23586712455422 CG8065 CG8065, isoform C - - - - 40915 1706.20 0.45 0.445 -0.0161196653632772 Down 0.0413749834896315 CG2616 CG2616, isoform B K03454|1|8e-23|108|xla:100137670|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane - GO:0006810//transport 3772438 498.00 0.25 0.01 -4.64385618977472 Down 0.24085325584467 CG33912 CG33912 K09255|1|1e-09|62.4|dpe:Dper_GL18753|Rel/ankyrin family, other - - - 47763 2537.00 0.12 0.085 -0.497499659470817 Down 0.0618808611808216 Abd-B abdominal B, isoform F K09300|1|2e-107|390|dme:Dmel_CG11648|homeobox protein abdominal-B and related proteins;K09294|2|1e-20|102|cbr:CBG23030|homeobox protein HoxA/B/C/D9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0035292//specification of segmental identity, trunk;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0008354//germ cell migration;GO:0046546//development of primary male sexual characteristics;GO:0042685//cardioblast cell fate specification;GO:0008406//gonad development;GO:0016202//regulation of striated muscle tissue development;GO:0000578//embryonic axis specification;GO:0048565//digestive tract development;GO:0035112//genitalia morphogenesis;GO:0046545//development of primary female sexual characteristics;GO:0007445;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0048070//regulation of developmental pigmentation;GO:0035292//specification of segmental identity, trunk;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0008354//germ cell migration;GO:0046546//development of primary male sexual characteristics;GO:0042685//cardioblast cell fate specification;GO:0008406//gonad development;GO:0016202//regulation of striated muscle tissue development;GO:0000578//embryonic axis specification;GO:0048565//digestive tract development;GO:0035112//genitalia morphogenesis;GO:0046545//development of primary female sexual characteristics;GO:0007445;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0048070//regulation of developmental pigmentation;GO:0035292//specification of segmental identity, trunk;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0008354//germ cell migration;GO:0046546//development of primary male sexual characteristics;GO:0042685//cardioblast cell fate specification;GO:0008406//gonad development;GO:0016202//regulation of striated muscle tissue development;GO:0000578//embryonic axis specification;GO:0048565//digestive tract development;GO:0035112//genitalia morphogenesis;GO:0046545//development of primary female sexual characteristics;GO:0007445;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0048070//regulation of developmental pigmentation;GO:0035292//specification of segmental identity, trunk;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0008354//germ cell migration;GO:0046546//development of primary male sexual characteristics;GO:0042685//cardioblast cell fate specification;GO:0008406//gonad development;GO:0016202//regulation of striated muscle tissue development;GO:0000578//embryonic axis specification;GO:0048565//digestive tract development;GO:0035112//genitalia morphogenesis;GO:0046545//development of primary female sexual characteristics;GO:0007445;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0048070//regulation of developmental pigmentation;GO:0035292//specification of segmental identity, trunk;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0008354//germ cell migration;GO:0046546//development of primary male sexual characteristics;GO:0042685//cardioblast cell fate specification;GO:0008406//gonad development;GO:0016202//regulation of striated muscle tissue development;GO:0000578//embryonic axis specification;GO:0048565//digestive tract development;GO:0035112//genitalia morphogenesis;GO:0046545//development of primary female sexual characteristics;GO:0007445;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0048070//regulation of developmental pigmentation 35916 2279.00 0.42 0.455 0.115477217419936 Up 0.0528661999735834 CG13742 CG13742, isoform E - - - - 33272 7072.00 12.875 19.405 0.591856000827505 Up 0.577697794214767 CG15824 CG15824, isoform C - - - - 32607 2060.77 11.505 10.51 -0.130498314261911 Down 0.209978866728305 TH1 TH1, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex - GO:0000122//negative regulation of transcription from RNA polymerase II promoter 33574 2379.00 5.04 8.785 0.80161855250846 Up 0.542728833707568 CG3213 CG3213 K10352|1|3e-10|67.8|mmu:544791|myosin heavy chain;K10396|4|1e-09|65.5|oaa:100076805|kinesin family member 5 GO:0030529//ribonucleoprotein complex - GO:0010467//gene expression 246670 558.00 46.99 32.095 -0.550005206748457 Down 0.622440892880729 Obp57a Odorant-binding protein 57a - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 36139 3158.98 5.02 4.01 -0.324085127495852 Down 0.280379078061022 dgo diego, isoform B K08848|1|1e-18|96.3|mdo:100016114|receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1] GO:0044424//intracellular part;GO:0044424//intracellular part - GO:0001736//establishment of planar polarity;GO:0001736//establishment of planar polarity 43500 736.00 4.57 4.725 0.0481201640503652 Up 0.0745938449346189 CG7593 CG7593 K00680|1|7e-26|117|dre:550325| [EC:2.3.1.-] - GO:0016407//acetyltransferase activity GO:0006909//phagocytosis 41803 1603.00 1.74 1.565 -0.15292464891611 Down 0.100250957601374 CG14860 CG14860 - - - - 37803 2285.76 5.39 6.455 0.260131822554685 Up 0.268293488310659 CG3735 CG3735, isoform B - - - - 35119 2390.00 1.73 1.455 -0.249752884728441 Down 0.132776383568881 tos tosca K10746|1|0.0|1411|dme:Dmel_CG10387|exonuclease 1 [EC:3.1.-.-] - GO:0016788//hydrolase activity, acting on ester bonds;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process 317934 1375.00 0.225 0.065 -1.79141337818858 Down 0.144102496367719 CG32241 CG32241 - - - - 48335 734.00 7.395 2.615 -1.49973920085213 Down 0.621648395192181 GstD2 glutathione S transferase D2 K00799|1|2e-123|441|dme:Dmel_CG4181|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity - 36952 5406.21 8.52 9.17 0.106068303369216 Up 0.166985867124554 cnk connector enhancer of ksr, isoform B K05724|1|5e-07|58.2|dre:100151562|FYVE, RhoGEF and PH domain containing 5/6 - - - 34244 889.00 0.225 0.345 0.616671360448494 Up 0.106524897635715 aust australin, isoform B K11514|1|1e-08|60.1|aag:AaeL_AAEL011330|Borealin GO:0005875//microtubule associated complex - GO:0007140//male meiosis;GO:0033206//cytokinesis after meiosis 19835673 582.00 12.275 7.225 -0.764653531814014 Down 0.576409985470876 19835122 281.00 0.51 0.185 -1.46297197634255 Down 0.205950336811518 19834764 511.00 0.405 0.845 1.06102943339756 Up 0.232565050851935 43003 895.10 84.47 105.63 0.322508676894679 Up 0.537049266939638 veli veli, isoform C K12075|1|5e-17|88.6|aga:AgaP_AGAP000255|discs large protein GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex GO:0005488//binding - 37052 1991.00 2.075 0.86 -1.27070277153219 Down 0.391559899616959 CG10910 CG10910 K03254|1|6e-20|99.4|xla:443632|translation initiation factor eIF-3 subunit 10 - - - 36538 2353.00 0.505 0.395 -0.354430734574692 Down 0.0966186765288601 tum tumbleweed K08878|1|1e-17|92.0|bfo:BRAFLDRAFT_84243|breakpoint cluster region protein [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0005881//cytoplasmic microtubule GO:0005099//Ras GTPase activator activity;GO:0043169//cation binding;GO:0060089 GO:0000278//mitotic cell cycle;GO:0007265//Ras protein signal transduction;GO:0016055//Wnt receptor signaling pathway;GO:0045165//cell fate commitment;GO:0051301//cell division;GO:0048812//neuron projection morphogenesis;GO:0045185//maintenance of protein location;GO:0035466 117332 1206.18 78.555 73.965 -0.086860351948232 Down 0.22972526746797 Rheb Ras homolog enriched in brain ortholog, isoform B K07208|1|8e-100|363|dsi:Dsim_GD19794|Ras homolog enriched in brain GO:0044464//cell part;GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0006412//translation;GO:0035556//intracellular signal transduction;GO:0016049//cell growth;GO:0022402//cell cycle process;GO:0042254//ribosome biogenesis;GO:0007444//imaginal disc development;GO:0006950//response to stress;GO:0006412//translation;GO:0035556//intracellular signal transduction;GO:0016049//cell growth;GO:0022402//cell cycle process;GO:0042254//ribosome biogenesis;GO:0007444//imaginal disc development;GO:0006950//response to stress 40566 3630.00 16.88 16.545 -0.0289196123946462 Down 0.0886276581693303 CG14650 CG14650 K09534|1|0.0|1405|dme:Dmel_CG14650|DnaJ homolog subfamily C member 14 - GO:0005515//protein binding - 42527 2124.00 65.92 75.06 0.187328047703757 Up 0.392187293620394 CG3308 CG3308 K03424|1|0.0|637|dme:Dmel_CG3308|TatD DNase family protein [EC:3.1.21.-] - GO:0004520//endodeoxyribonuclease activity - 41811 784.00 2.055 2.01 -0.0319428925027542 Down 0.0499603751155726 RpL10Aa ribosomal protein L10Aa K02865|1|7e-100|363|dme:Dmel_CG3843|large subunit ribosomal protein L10Ae - - - 39138 1278.00 9.835 10.735 0.126325233580243 Up 0.203209615638621 CG18178 CG18178, isoform B - - GO:0005488//binding - 43096 3429.00 19.245 22.975 0.255581190365558 Up 0.406947563069608 RASSF8 RASSF8 K09856|1|3e-27|124|dre:393334|Ras association domain-containing protein 8 - - GO:0023060 33540 2798.54 7.315 7.77 0.0870567342692232 Up 0.133932109364681 CG9664 CG9664, isoform D K05680|1|2e-116|420|cin:100179107|ATP-binding cassette, subfamily G (WHITE), member 4;K05679|4|4e-110|399|tgu:100222171|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 38397 558.66 725.34 702.28 -0.0466110610373517 Down 0.162098798045172 RpL28 ribosomal protein L28, isoform G K02903|1|2e-60|231|dya:Dyak_GE20698|large subunit ribosomal protein L28e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 33019 1245.73 174.31 193.74 0.152466508896555 Up 0.350085853916259 AnnX annexin B10, isoform B - - GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding - 31045 2496.00 24.12 29.66 0.298288690554546 Up 0.466120723814556 CG3703 CG3703 - - - - 40451 1213.29 541.49 495.68 -0.127525645779774 Down 0.323239994716682 RpLP0 ribosomal protein LP0, isoform B K02941|1|6e-156|550|dsi:Dsim_GD15019|large subunit ribosomal protein LP0 GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit GO:0016835//carbon-oxygen lyase activity;GO:0005198//structural molecule activity GO:0006259//DNA metabolic process;GO:0022613//ribonucleoprotein complex biogenesis;GO:0006412//translation 3771730 666.00 0.92 0.375 -1.29474326556113 Down 0.269911504424779 CG33666 CG33666 - - - - 246620 2303.00 8.975 10.815 0.269049821251565 Up 0.339717342491084 Tdc2 tyrosine decarboxylase 2 K01593|1|0.0|657|cbr:CBG00668|aromatic-L-amino-acid decarboxylase [EC:4.1.1.28] - GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0043436;GO:0033057;GO:0030534//adult behavior 43546 1213.39 20.735 30.47 0.555321452780524 Up 0.60299167877427 CG15522 CG15522, isoform B - - - - 8674050 3446.00 0.04 0.03 -0.415037499278844 Down 0.0473847576277902 CG42504 CG42504 K03364|1|2e-12|75.5|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0044464//cell part - - 32387 4879.33 16.925 19.795 0.225980233567738 Up 0.36619997358341 dpr8 dpr8, isoform B K06768|1|1e-06|57.0|dre:100002762|Down syndrome cell adhesion molecule like 1;K06773|2|2e-06|56.2|dre:449538|opioid binding protein/cell adhesion molecule-like;K06774|3|2e-06|56.2|mmu:235106|neurotrimin - - - 38873 5227.96 12.105 15.375 0.344983331115028 Up 0.439043719455818 CG32369 CG32369, isoform C - - GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled GO:0019538//protein metabolic process 5740347 564.00 10.315 15.54 0.591242682521225 Up 0.555342755250297 blos3 biogenesis of lysosome-related organelles complex 1, subunit 3 - GO:0044424//intracellular part GO:0005488//binding - 3771915 1976.00 4.95 3.64 -0.443490074768276 Down 0.338132347113988 CG33672 CG33672 K00869|1|0.0|725|dme:Dmel_CG33671|mevalonate kinase [EC:2.7.1.36] GO:0044424//intracellular part GO:0016301//kinase activity;GO:0032559 GO:0006720//isoprenoid metabolic process;GO:0006796//phosphate-containing compound metabolic process 12798318 799.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 CG43104 CG43104 - - - - 5740437 510.00 0.085 0.095 0.160464672193246 Up 0.045238409721305 CG34196 CG34196 - - - - 31792 5578.85 43.815 36.505 -0.263330778972965 Down 0.449940562673359 Nrg neuroglian, isoform I K06756|1|4e-162|573|hsa:4897|neuronal cell adhesion molecule;K06757|3|5e-158|559|gga:419824|neurofascin GO:0005918//septate junction;GO:0042995//cell projection;GO:0005918//septate junction;GO:0042995//cell projection;GO:0005918//septate junction;GO:0042995//cell projection;GO:0005918//septate junction;GO:0042995//cell projection;GO:0005918//septate junction;GO:0042995//cell projection;GO:0005918//septate junction;GO:0042995//cell projection GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0007043//cell-cell junction assembly;GO:0048812//neuron projection morphogenesis;GO:0007444//imaginal disc development;GO:0016337//cell-cell adhesion;GO:0035150//regulation of tube size;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007272;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0021675//nerve development;GO:0048588//developmental cell growth;GO:0035006//melanization defense response;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0007043//cell-cell junction assembly;GO:0048812//neuron projection morphogenesis;GO:0007444//imaginal disc development;GO:0016337//cell-cell adhesion;GO:0035150//regulation of tube size;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007272;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0021675//nerve development;GO:0048588//developmental cell growth;GO:0035006//melanization defense response;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0007043//cell-cell junction assembly;GO:0048812//neuron projection morphogenesis;GO:0007444//imaginal disc development;GO:0016337//cell-cell adhesion;GO:0035150//regulation of tube size;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007272;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0021675//nerve development;GO:0048588//developmental cell growth;GO:0035006//melanization defense response;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0007043//cell-cell junction assembly;GO:0048812//neuron projection morphogenesis;GO:0007444//imaginal disc development;GO:0016337//cell-cell adhesion;GO:0035150//regulation of tube size;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007272;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0021675//nerve development;GO:0048588//developmental cell growth;GO:0035006//melanization defense response;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0007043//cell-cell junction assembly;GO:0048812//neuron projection morphogenesis;GO:0007444//imaginal disc development;GO:0016337//cell-cell adhesion;GO:0035150//regulation of tube size;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007272;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0021675//nerve development;GO:0048588//developmental cell growth;GO:0035006//melanization defense response;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0007043//cell-cell junction assembly;GO:0048812//neuron projection morphogenesis;GO:0007444//imaginal disc development;GO:0016337//cell-cell adhesion;GO:0035150//regulation of tube size;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007272;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0021675//nerve development;GO:0048588//developmental cell growth;GO:0035006//melanization defense response;GO:0043062//extracellular structure organization;GO:0021782//glial cell development 38816 2350.68 51.565 56.875 0.141402478798088 Up 0.312508255184256 qm quemao, isoform C K00804|1|0.0|671|dme:Dmel_CG8593|geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29] GO:0044297//cell body;GO:0015934//large ribosomal subunit;GO:0044297//cell body;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0004659//prenyltransferase activity;GO:0005198//structural molecule activity;GO:0004659//prenyltransferase activity GO:0007276//gamete generation;GO:0007052//mitotic spindle organization;GO:0006720//isoprenoid metabolic process;GO:0009790//embryo development;GO:0007276//gamete generation;GO:0007052//mitotic spindle organization;GO:0006720//isoprenoid metabolic process;GO:0009790//embryo development 39026 2740.30 12.145 9.58 -0.342264928899685 Down 0.410711927090213 CG5026 CG5026, isoform C K01112|1|1e-62|241|gga:422731| [EC:3.1.3.-] - GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 41248 1591.00 54.125 47.69 -0.182608337107092 Down 0.36851142517501 Timp tissue inhibitor of metalloproteases - GO:0043005//neuron projection;GO:0031012//extracellular matrix GO:0005488//binding;GO:0004866//endopeptidase inhibitor activity GO:0009416//response to light stimulus;GO:0060560//developmental growth involved in morphogenesis;GO:0007560//imaginal disc morphogenesis;GO:0007424//open tracheal system development;GO:0022408//negative regulation of cell-cell adhesion;GO:0030198//extracellular matrix organization 38149 3714.52 33.945 22.92 -0.566592041231144 Down 0.61121384229296 CG2469 CG2469, isoform B K09667|1|7e-13|77.0|cbr:CBG16605|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - - - 34495 4702.31 13.525 16.025 0.244695762791926 Up 0.358572183331132 Nos nitric oxide synthase, isoform K K13253|1|0.0|2439|dya:Dyak_GE13295|nitric-oxide synthase, invertebrate [EC:1.14.13.39] GO:0005737//cytoplasm;GO:0005737//cytoplasm;GO:0005737//cytoplasm GO:0005515//protein binding;GO:0030554//adenyl nucleotide binding;GO:0005506//iron ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030554//adenyl nucleotide binding;GO:0005506//iron ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030554//adenyl nucleotide binding;GO:0005506//iron ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0003723//RNA binding GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0007143//female meiosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0031124//mRNA 3'-end processing;GO:0048513//organ development;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0019827//stem cell maintenance;GO:0040008//regulation of growth;GO:0007309//oocyte axis specification;GO:0006915//apoptotic process;GO:0000578//embryonic axis specification;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0006260//DNA replication;GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0007143//female meiosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0031124//mRNA 3'-end processing;GO:0048513//organ development;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0019827//stem cell maintenance;GO:0040008//regulation of growth;GO:0007309//oocyte axis specification;GO:0006915//apoptotic process;GO:0000578//embryonic axis specification;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0006260//DNA replication;GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0007143//female meiosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0031124//mRNA 3'-end processing;GO:0048513//organ development;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0019827//stem cell maintenance;GO:0040008//regulation of growth;GO:0007309//oocyte axis specification;GO:0006915//apoptotic process;GO:0000578//embryonic axis specification;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0006260//DNA replication 31438 1409.76 2.345 1.96 -0.258734268400168 Down 0.16137234183067 CG42749 CG42749, isoform D - GO:0044423 - - 318018 996.00 0.12 0.095 -0.337034987277571 Down 0.0606260731739532 CG32413 CG32413 K00683|1|4e-32|138|dme:Dmel_CG5976|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 34114 3980.72 59.25 68.505 0.209394136426526 Up 0.414080042266543 CG8475 CG8475, isoform C K07190|1|0.0|1252|dme:Dmel_CG8475|phosphorylase kinase alpha/beta subunit - GO:0015926//glucosidase activity;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0015926//glucosidase activity;GO:0019887//protein kinase regulator activity;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006006//glucose metabolic process;GO:0006006//glucose metabolic process 31227 1780.00 2.94 4.155 0.49903232193398 Up 0.334896314885748 gt giant K09062|1|5e-124|444|dme:Dmel_CG7952|bZIP factor, other - - - 19834952 571.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 33096 1156.00 0.27 0.925 1.77649395835284 Up 0.31036190727777 CG14579 CG14579 - - - - 38763 1814.00 94.66 119.615 0.337571491014969 Up 0.553823801347246 CG9953 CG9953 K09649|1|2e-71|270|mdo:100019475|protease, serine, 16 (thymus) [EC:3.4.-.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 42975 3296.00 12.01 7.075 -0.763434097986389 Down 0.573372077664773 CG31121 CG31121, isoform B K05684|1|4e-30|134|mdo:100033372|ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2) GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0051234//establishment of localization 33317 776.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 a5 antennal protein 5 - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0005543//phospholipid binding GO:0006325//chromatin organization 34920 2287.00 0.135 0.13 -0.0544477840223765 Down 0.0419363360190199 CG18480 CG18480, isoform C K10159|1|3e-11|70.9|bta:281534|toll-like receptor 2;K08120|2|8e-11|69.3|dre:65228|asporin;K06838|3|7e-10|66.2|hsa:6585|slit 1 - GO:0005488//binding - 14462652 452.00 0.095 0.13 0.452512204697507 Up 0.067956676793026 39883 5454.00 11.01 10.765 -0.0324661493971353 Down 0.081197992339189 CG9715 CG9715 K12597|1|2e-54|215|aga:AgaP_AGAP006128|protein AIR1/2 - GO:0046872//metal ion binding - 42063 2230.53 36.31 34.305 -0.0819480636673785 Down 0.195978074230617 kuk kugelkern, isoform C - - - - 42875 935.55 29.585 31.19 0.076217657624138 Up 0.188515387663453 CG5515 CG5515, isoform D K08860|1|2e-06|53.5|dmo:Dmoj_GI22205|eukaryotic translation initiation factor 2-alpha kinase [EC:2.7.11.1] - - - 37134 5819.08 9.13 10.13 0.149947408816916 Up 0.222229560163783 GEFmeso guanine nucleotide exchange factor in mesoderm, isoform G K08810|1|4e-23|111|tca:656919|triple functional domain protein [EC:2.7.11.-];K12365|4|8e-22|107|dre:570984|phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein;K05769|5|8e-22|107|bta:505852|Rho guanine nucleotide exchange factor 4 - - - 31986 686.00 0.52 0.78 0.584962500721156 Up 0.15453704926694 CG15296 CG15296, isoform B - - - - 34758 491.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 Vm34Ca vitelline membrane 34Ca - - - - 38999 515.00 0.245 0.11 -1.15527822547791 Down 0.127228899749042 Cp15 chorion protein 15 - GO:0030312//external encapsulating structure GO:0005198//structural molecule activity GO:0032501//multicellular organismal process 38695 4198.76 10.425 11.96 0.198170005866079 Up 0.288535200105666 CG13293 CG13293, isoform E - - - - 38987 1544.00 8.8 7.95 -0.146548663352942 Down 0.2085259542993 GAPsec GTPase activating protein, SECIS-dependent read-through K13136|1|1e-13|78.2|nvi:100114269|gem associated protein 8 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 38934 1055.00 25.6 21.115 -0.27787556308606 Down 0.435510500594373 Sbp2 SECIS-binding protein 2 - - - - 3355066 2977.65 19.42 21.005 0.113189585067325 Up 0.224342887333245 CG17684 CG17684, isoform D K01278|1|9e-98|358|nvi:100120008|dipeptidyl-peptidase 4 [EC:3.4.14.5];K08674|5|3e-92|340|tgu:100228501|fibroblast activation protein, alpha [EC:3.4.21.-] GO:0044464//cell part - GO:0019538//protein metabolic process 318563 1671.00 203.39 189.96 -0.0985530871831559 Down 0.260929863954563 CG31030 CG31030, isoform B K03662|1|4e-13|76.6|tca:663029|V-type H+-transporting ATPase S1 subunit [EC:3.6.3.14] GO:0033176;GO:0033176 GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process 19835575 801.00 0.67 0.285 -1.23319917629303 Down 0.220248315942412 8674100 2767.00 10.24 12.05 0.234817431117324 Up 0.320169066173557 CG42511 CG42511 - GO:0031224//intrinsic to membrane - - 326177 1184.00 59.78 53.715 -0.154337877636414 Down 0.329348831065909 CG31937 CG31937 K00120|1|3e-157|554|dme:Dmel_CG31937| [EC:1.1.-.-];K11165|2|2e-44|179|dre:751626|dehydrogenase/reductase SDR family member 7 [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 14462771 655.00 0.125 0.075 -0.736965594166206 Down 0.0760797781006472 33114 2026.00 17.495 14.315 -0.289414994240497 Down 0.412329943204332 Sep1 septin 1 K04557|1|7e-117|421|xtr:100125069|peanut-like protein 1 (cell division control related protein 1) GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0032156 GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding GO:0006915//apoptotic process;GO:0000087//M phase of mitotic cell cycle;GO:0051301//cell division;GO:0007275//multicellular organismal development 246530 955.00 0.215 0.455 1.0815298854966 Up 0.1670519085986 CG30287 CG30287 K09632|1|3e-31|135|gga:427531|chymotrypsin-like protease [EC:3.4.21.-];K01312|5|1e-26|120|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40988 1643.00 6.485 6.46 -0.00557240955777449 Down 0.0432901862369568 Coq2 coenzyme Q biosynthesis protein 2 K06125|1|0.0|704|dme:Dmel_CG9613|4-hydroxybenzoate hexaprenyltransferase [EC:2.5.1.-] GO:0031224//intrinsic to membrane;GO:0044452;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0044451//nucleoplasm part GO:0034062//RNA polymerase activity;GO:0002094//polyprenyltransferase activity GO:0016091;GO:0006743//ubiquinone metabolic process;GO:0006351//transcription, DNA-dependent 35405 2359.00 25.745 30.19 0.229778486716168 Up 0.397833839651301 Tsp39D tetraspanin 39D K06497|1|2e-127|456|dme:Dmel_CG8666|CD63 antigen GO:0031224//intrinsic to membrane - - 31084 1114.00 0.64 0.05 -3.67807190511264 Down 0.333806630563994 png pan gu K08286|1|2e-168|591|dme:Dmel_CG11420|protein-serine/threonine kinase [EC:2.7.11.-];K08800|2|1e-31|137|mmu:74137|NUAK family, SNF1-like kinase [EC:2.7.11.1];K08857|4|2e-31|136|bfo:BRAFLDRAFT_205444|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] - - - 38087 1924.00 6.73 4.975 -0.435909979179306 Down 0.38148857482499 CG13895 CG13895, isoform B - GO:0044427//chromosomal part GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression 42635 1141.69 28.81 37.55 0.382243247241764 Up 0.538799366001849 pinta prolonged depolarization afterpotential (PDA) is not apparent, isoform B K10693|1|2e-07|57.0|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] - GO:0019840//isoprenoid binding GO:0006726//eye pigment biosynthetic process;GO:0007165//signal transduction 33799 1090.00 0.25 0.17 -0.556393348524385 Down 0.0892550521727645 CG14007 CG14007 - - - - 31165 2521.74 24.95 25.23 0.0161003907516772 Up 0.0753203011491217 usp ultraspiracle, isoform B K14030|1|0.0|769|dme:Dmel_CG4380|nuclear receptor subfamily 2 group B member 4 - - - 34867 679.00 3.255 4.6 0.49897631777874 Up 0.349326376964734 Mst35Bb Male-specific-transcript-35Bb - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding - 40886 415.00 4.645 11.26 1.27745632569758 Up 0.646281865011227 Mst84Dd Male-specific RNA 84Dd - - - - 43128 2612.68 24.885 28.37 0.18908976359734 Up 0.350283978338397 SppL signal peptide peptidase-like, isoform F K09598|1|0.0|687|dme:Dmel_CG17370|signal peptide peptidase-like 3 [EC:3.4.23.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004190//aspartic-type endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity GO:0006915//apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006915//apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006915//apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006915//apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006915//apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process 33276 4153.53 33.135 36.485 0.138947534345577 Up 0.297120591731607 CG4341 CG4341, isoform C K09667|1|2e-26|122|bfo:BRAFLDRAFT_117202|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - - - 5740820 299.00 0.01 1.245 6.96000193206808 Up 0.553097345132743 CG41281 CG41281 K12559|1|1e-10|64.7|xla:445000|myosin X GO:0015629//actin cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0023060 39773 1500.00 0.135 0.035 -1.94753258010586 Down 0.11260071324792 CG13073 CG13073 - - - - 47220 5850.57 27.48 26.06 -0.0765449202499653 Down 0.184354774798574 Fur1 furin 1, isoform J K01349|1|0.0|1373|dme:Dmel_CG10772|furin [EC:3.4.21.75] GO:0031228//intrinsic to Golgi membrane;GO:0031228//intrinsic to Golgi membrane;GO:0031228//intrinsic to Golgi membrane;GO:0031228//intrinsic to Golgi membrane;GO:0031228//intrinsic to Golgi membrane;GO:0031228//intrinsic to Golgi membrane GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 59150 1605.67 28.82 26.72 -0.109150327700695 Down 0.238574824990094 CG18766 CG18766, isoform C - - GO:0005506//iron ion binding;GO:0005506//iron ion binding - 39557 3228.70 56.855 50.22 -0.179025201035952 Down 0.369369964337604 Hsc70Cb Hsc70Cb, isoform I K09485|1|0.0|1506|dme:Dmel_CG6603|heat shock protein 110kDa;K09489|5|0.0|645|dre:335865|heat shock 70kDa protein 4 - GO:0032559;GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding;GO:0032559;GO:0005515//protein binding - 41260 15371.07 17.675 19.5 0.141763908940212 Up 0.263340377757232 Bruce bruce, isoform E K10586|1|0.0|8917|dme:Dmel_CG6303|baculoviral IAP repeat-containing protein 6 (apollon) [EC:6.3.2.19] GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0007281//germ cell development;GO:0006351//transcription, DNA-dependent;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process 31383 1693.00 3.66 3.895 0.0897796797776268 Up 0.0974111742174085 CG3568 CG3568 - - - - 38831 1542.00 27.795 22.08 -0.332085209970253 Down 0.48632941487254 Rac2 Rac2, isoform B K04392|1|1e-103|376|dpe:Dper_GL24253|Ras-related C3 botulinum toxin substrate 1 GO:0042995//cell projection GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0007015//actin filament organization;GO:0007017//microtubule-based process;GO:0007424//open tracheal system development;GO:0019094//pole plasm mRNA localization;GO:0002682//regulation of immune system process;GO:0006952//defense response;GO:0055002//striated muscle cell development;GO:0007392;GO:0007409//axonogenesis;GO:0034331;GO:0006935//chemotaxis;GO:0042051//compound eye photoreceptor development;GO:0010591//regulation of lamellipodium assembly;GO:0000768//syncytium formation by plasma membrane fusion;GO:0002252;GO:0007297//ovarian follicle cell migration;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006909//phagocytosis;GO:0048588//developmental cell growth;GO:0042386//hemocyte differentiation 43101 1082.00 11.935 13.765 0.205806043513785 Up 0.311022322018227 CG4743 CG4743 K03454|1|5e-14|78.6|nve:NEMVE_v1g238240|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 246629 1946.51 5.665 6.145 0.117337054552146 Up 0.150970809668472 CG30466 CG30466, isoform B - - - - 246484 962.00 26.9 21.02 -0.355843503481808 Down 0.502575617487782 CG30151 CG30151 - - - - 38080 2305.42 0.39 1.625 2.05889368905357 Up 0.422566371681416 CG17129 CG17129, isoform C - - - - 41022 1365.49 16.62 21.44 0.367384523687428 Up 0.489598467837802 Dhod dihydroorotate dehydrogenase, isoform D K00254|1|0.0|761|dme:Dmel_CG9741|dihydroorotate dehydrogenase [EC:1.3.5.2] GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0004152//dihydroorotate dehydrogenase activity;GO:0004152//dihydroorotate dehydrogenase activity GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0009174;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0009174 34480 655.00 19.535 19.45 -0.00629110031011883 Down 0.053625676925109 Dpy-30L1 Dpy-30-like 1 - - - - 42831 1562.00 17.65 12.28 -0.523357622788363 Down 0.544677057191917 CG5854 CG5854 - - GO:0048037//cofactor binding GO:0008152//metabolic process 45320 12484.19 46.6 43.53 -0.0983199347537417 Down 0.238442742042002 trol terribly reduced optic lobes, isoform BA K06255|1|0.0|980|gga:429806|heparan sulfate proteoglycan 2 (perlecan) GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix - GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity;GO:0050896//response to stimulus;GO:0045165//cell fate commitment;GO:0035090//maintenance of apical/basal cell polarity 34892 1411.64 6.25 8.2 0.391767719955996 Up 0.387135120855898 Pol32 Pol32, isoform C K03504|1|2e-150|532|dme:Dmel_CG3975|DNA polymerase delta subunit 3 - - - 19835787 641.00 0.9 0.91 0.0159415438690215 Up 0.0413749834896315 - CG43784 - - - - 35586 1303.00 66.1 51.585 -0.357698655147107 Down 0.551248183859464 CG9436 CG9436 K00011|1|0.0|644|dme:Dmel_CG9436|aldehyde reductase [EC:1.1.1.21] - GO:0003824//catalytic activity GO:0044237//cellular metabolic process 33130 1358.00 0.52 0.595 0.194378045166851 Up 0.0722823933430194 tilB touch insensitive larva B K11092|1|9e-12|71.6|phu:Phum_PHUM308180|U2 small nuclear ribonucleoprotein A';K03994|4|2e-10|67.0|dre:565774|complement component 5 - - GO:0050877//neurological system process;GO:0008049//male courtship behavior;GO:0009266//response to temperature stimulus 35113 2427.00 3.725 4.58 0.29810717274742 Up 0.255745608241976 Atac2 Ada2a-containing complex component 2 - - GO:0046914//transition metal ion binding;GO:0016407//acetyltransferase activity - 38730 4303.00 4.79 4.835 0.0134902337406608 Up 0.0472856954167217 CG13300 CG13300 - - - GO:0008152//metabolic process 19836090 787.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 33954 865.23 9.7 14.495 0.579498680986907 Up 0.544743098665962 CG17377 CG17377, isoform F - - - - 31532 2674.71 27.96 24.665 -0.180899073380944 Down 0.337405890899485 CG5966 CG5966, isoform B K01046|1|0.0|1128|dme:Dmel_CG5966|triacylglycerol lipase [EC:3.1.1.3] - - - 33704 1772.88 14.16 14.105 -0.00561459949742592 Down 0.0492999603751156 betaggt-I beta subunit of type I geranylgeranyl transferase, isoform B K11713|1|0.0|815|dme:Dmel_CG3469|geranylgeranyl transferase type-1 subunit beta [EC:2.5.1.59] - GO:0004661//protein geranylgeranyltransferase activity GO:0009790//embryo development;GO:0007264//small GTPase mediated signal transduction 41387 4726.00 12.73 7.78 -0.710390358915166 Down 0.566569805838066 Mrp4 multidrug resistance protein 4 ortholog K05673|1|0.0|1705|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|2|0.0|1561|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0015893//drug transport;GO:0007450//dorsal/ventral pattern formation, imaginal disc 31407 1878.00 1.67 2.13 0.351005327751786 Up 0.193798705587109 CG7024 CG7024 K00161|1|0.0|861|dme:Dmel_CG7024|pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] GO:0043234//protein complex;GO:0043227//membrane-bounded organelle GO:0004738//pyruvate dehydrogenase activity GO:0032787//monocarboxylic acid metabolic process;GO:0006007//glucose catabolic process 37844 1709.00 1.11 0.855 -0.376563351464208 Down 0.142616563201691 ppk29 pickpocket 29, isoform H K10876|1|1e-24|114|dgr:Dgri_GH20163|RAD54-like protein 2 [EC:3.6.1.-] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005261//cation channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0005261//cation channel activity;GO:0032559;GO:0005261//cation channel activity;GO:0003676//nucleic acid binding;GO:0005261//cation channel activity;GO:0016787//hydrolase activity GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport 40358 2462.00 15.44 15.88 0.0405381598748772 Up 0.104543653414344 Pc polycomb K11455|1|2e-140|500|dme:Dmel_CG32443|chromobox protein 8;K11453|3|3e-26|120|aag:AaeL_AAEL014098|chromobox protein 6 GO:0031519//PcG protein complex;GO:0031981//nuclear lumen;GO:0005720//nuclear heterochromatin GO:0030528//transcription regulator activity;GO:0042393//histone binding GO:0016458//gene silencing;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0042551//neuron maturation;GO:0035292//specification of segmental identity, trunk 33312 2477.00 2.96 11.12 1.90948770709456 Up 0.693039228635583 CG42329 CG42329 K00680|1|3e-106|386|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 39422 2303.36 11.955 12.385 0.0509797385347351 Up 0.110718531237617 CG10660 CG10660, isoform D - - - - 33298 1272.00 20.72 12.195 -0.76473424489037 Down 0.625875049531106 Tango14 transport and golgi organization 14, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity - 36111 989.00 54.085 54.24 0.00412864775353428 Up 0.0462620525690133 CG17765 CG17765 K08585|1|3e-17|89.4|cqu:CpipJ_CPIJ010278|calpain, invertebrate [EC:3.4.22.-];K08583|4|5e-16|85.1|dre:560033|calpain, small subunit 1 - GO:0046872//metal ion binding - 41326 2566.00 0.83 1.115 0.42586046857338 Up 0.157277770439836 CG4706 CG4706 K01681|1|0.0|1551|dme:Dmel_CG4706|aconitate hydratase 1 [EC:4.2.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0051536//iron-sulfur cluster binding;GO:0016836//hydro-lyase activity GO:0009060//aerobic respiration 38122 564.00 0.3 0.165 -0.862496476250065 Down 0.120723814555541 LysX lysozyme X K01185|1|3e-83|306|dme:Dmel_CG9120|lysozyme [EC:3.2.1.17];K13915|2|7e-64|242|dan:Dana_GF10076|lysozyme C [EC:3.2.1.17];K01183|5|2e-61|234|dme:Dmel_CG9118|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0006950//response to stress;GO:0009056//catabolic process 5740303 2074.28 0.305 0.46 0.592824618494126 Up 0.117157574957073 CG34386 CG34386, isoform D - - - - 19835185 1024.00 1.475 0.995 -0.567946523705555 Down 0.21559239202219 36263 3918.00 14.305 15.42 0.108283267591851 Up 0.203473781534804 Sln silnoon K11810|1|2e-38|162|bfo:BRAFLDRAFT_210112|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 12 - GO:0046943//carboxylic acid transmembrane transporter activity GO:0006810//transport 31507 4296.00 7.64 8.22 0.105565755645934 Up 0.158994848765024 CG42699 CG42699 K10352|1|4e-11|71.2|dgr:Dgri_GH22039|myosin heavy chain - - - 31402 1490.05 44.13 42.89 -0.0411184313404299 Down 0.12650244353454 CG3009 CG3009, isoform D K01047|1|0.0|674|dme:Dmel_CG3009|phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 10178817 283.00 0.955 0.935 -0.0305343681481121 Down 0.0445449742438251 CG42869 CG42869 - - - - 38338 7632.64 5.4 4.975 -0.11826288161982 Down 0.143210936468102 Mrtf Myocardin-related transcription factor, isoform H - - GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0007472//wing disc morphogenesis;GO:0007297//ovarian follicle cell migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0060541//respiratory system development;GO:0007010//cytoskeleton organization;GO:0007509//mesoderm migration involved in gastrulation;GO:0007472//wing disc morphogenesis;GO:0007297//ovarian follicle cell migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0060541//respiratory system development;GO:0007010//cytoskeleton organization;GO:0007509//mesoderm migration involved in gastrulation 35439 1425.00 27.515 8.17 -1.75181034518368 Down 0.739004094571391 CG6675 CG6675, isoform C K01059|1|2e-36|153|dme:Dmel_CG4582|lipoprotein lipase [EC:3.1.1.34];K01046|3|5e-32|139|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|3|5e-32|139|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 42732 1291.00 0.035 0.115 1.71620703399941 Up 0.101736890767402 CG6738 CG6738 K01436|1|0.0|805|dme:Dmel_CG6738|aminoacylase [EC:3.5.1.14] GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding GO:0006519 40036 939.66 89.955 90.165 0.00336404725583464 Up 0.046559239202219 Chmp1 charged multivesicular body protein 1, isoform B K12197|1|6e-94|343|dsi:Dsim_GD12332|charged multivesicular body protein 1 - - GO:0006810//transport 50271 420.00 0.22 0.01 -4.4594316186373 Down 0.222989037115308 CG13069 CG13069 - - - - 37249 1201.00 13.11 16.19 0.304435300080812 Up 0.415136705851275 CG11007 CG11007, isoform B - - - - 41038 1746.63 2.615 4.585 0.810110787348113 Up 0.445284638753137 CG8145 CG8145, isoform C K09228|1|2e-29|130|rno:682131|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 40543 2530.00 8.375 10.195 0.283700679784099 Up 0.344010038304055 CG9791 CG9791 - GO:0031980 GO:0004386//helicase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0032392//DNA geometric change 34027 1087.00 5.05 1.95 -1.37280926388955 Down 0.556564522520143 CG6055 CG6055, isoform B K06560|1|6e-07|55.1|cin:100176392|mannose receptor, C type - GO:0030246//carbohydrate binding - 10178901 429.00 3.21 3.935 0.293790338385183 Up 0.233885880332849 CG42659 CG42659 - - - - 39624 1440.00 11.015 10.48 -0.0718307781634328 Down 0.132710342094836 CG5114 CG5114, isoform B K02084|1|2e-12|73.6|nve:NEMVE_v1g160179|apoptotic protease-activating factor;K01062|2|5e-10|65.9|isc:IscW_ISCW007420|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47];K12602|3|7e-10|65.5|ame:551226|WD repeat-containing protein 61;K11127|5|9e-10|65.1|bfo:BRAFLDRAFT_128562|telomerase protein component 1 - - - 32968 717.09 58.915 54.24 -0.119277818408458 Down 0.279256373002245 Sec61gamma Sec61 gamma subunit, isoform C K07342|1|3e-32|138|dya:Dyak_GE15861|protein transport protein SEC61 subunit gamma and related proteins GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0071256 GO:0008320//protein transmembrane transporter activity GO:0007033//vacuole organization;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006914//autophagy 33492 1785.00 39.49 41.195 0.0609818746356997 Up 0.163617751948223 CG8814 CG8814 K13239|1|2e-11|70.9|mcc:709579|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8] - GO:0008144//drug binding;GO:0030234//enzyme regulator activity;GO:0005504//fatty acid binding - 42144 1220.00 0.13 0.155 0.253756592245783 Up 0.0579183727380795 CG17801 CG17801 K09228|1|2e-20|99.8|ecb:100064925|KRAB domain-containing zinc finger protein - - - 32327 1608.00 9.715 7.86 -0.305684683326738 Down 0.358010830801744 CG11158 CG11158 K01239|1|4e-37|156|xla:379157|purine nucleosidase [EC:3.2.2.1] - - - 33601 7477.25 19.175 22.195 0.211008130934798 Up 0.356491876898692 CG43707 CG43707, isoform I K12490|1|6e-07|57.8|nve:NEMVE_v1g214998|Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein;K12331|2|2e-06|56.2|ssc:100157291|Rho guanine nucleotide exchange factor 11;K07532|4|2e-06|55.8|rno:367072|Rho guanine nucleotide exchange factor 12 - GO:0005488//binding - 35102 3006.39 12.75 12.605 -0.0165011288876805 Down 0.063333773609827 CG10283 CG10283, isoform D - - - - 36912 4141.78 43.115 47.25 0.132124449329047 Up 0.291903315281997 Ehbp1 Eps15 homology domain containing protein-binding protein 1, isoform I K05699|1|7e-19|97.1|dwi:Dwil_GK25747|actinin alpha - - - 19835850 701.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 33381 1209.00 0.585 0.075 -2.96347412397489 Down 0.295436534143442 Or22c odorant receptor 22c K08471|1|0.0|721|dme:Dmel_CG15377|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33938 887.00 0.315 0.54 0.777607578663552 Up 0.149881125346718 CG11329 CG11329, isoform B - - GO:0046914//transition metal ion binding - 19835356 425.00 0.105 0.27 1.36257007938471 Up 0.139875842028794 326138 1603.54 5.445 3.435 -0.664621949898807 Down 0.431514991414608 CG31431 CG31431, isoform C K01217|1|3e-13|76.6|ecb:100146682|L-iduronidase [EC:3.2.1.76];K05094|2|2e-10|67.4|dre:58129|fibroblast growth factor receptor 3 [EC:2.7.10.1];K05093|3|5e-09|62.8|bfo:BRAFLDRAFT_84835|fibroblast growth factor receptor 2 [EC:2.7.10.1];K04362|4|2e-08|60.8|dre:30705|fibroblast growth factor receptor 1 [EC:2.7.10.1] GO:0031224//intrinsic to membrane - GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048513//organ development 3771787 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 42668 1183.00 1.055 1.545 0.550363839197189 Up 0.216715097080967 CG13843 CG13843 - GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0016787//hydrolase activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress 38851 3512.00 0.11 0.25 1.18442457113743 Up 0.127460044908202 CG14838 CG14838 K11143|1|4e-15|84.3|api:100160708|dynein intermediate chain 2, axonemal GO:0005875//microtubule associated complex GO:0016887//ATPase activity - 35138 2007.48 17.375 18.78 0.112184085155542 Up 0.217606656980584 CG17323 CG17323, isoform E K00699|1|0.0|1070|dme:Dmel_CG17323|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups GO:0002118//aggressive behavior 36982 4255.00 0.19 0.3 0.658963082164933 Up 0.10299167877427 CG43370 CG43370 - - - - 39815 809.00 0.11 0.25 1.18442457113743 Up 0.127460044908202 Cpr72Eb cuticular protein 72Eb - - GO:0005198//structural molecule activity - 35670 1399.00 1.485 0.4 -1.8923910259134 Down 0.393243957205125 fa2h fatty acid 2-hydroylase - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0005506//iron ion binding;GO:0003824//catalytic activity GO:0006643//membrane lipid metabolic process;GO:0006631//fatty acid metabolic process 36926 1030.00 9.585 5.795 -0.725969770661679 Down 0.536785101043455 CG6984 CG6984 K07511|1|8e-27|120|dmo:Dmoj_GI20973|enoyl-CoA hydratase [EC:4.2.1.17] - - - 19835734 1231.00 4.675 3.585 -0.382993246073094 Down 0.302469951129309 34947 2842.71 9.19 12.265 0.416410467268568 Up 0.45644564786686 beat-Ia beaten path Ia, isoform B - - GO:0003824//catalytic activity GO:0048592//eye morphogenesis;GO:0007414//axonal defasciculation;GO:0007411//axon guidance 318776 1668.00 0.185 1.45 2.97045572438598 Up 0.449973583410382 CG31516 CG31516 - - - - 7354426 726.00 0.175 0.37 1.08017034868398 Up 0.151961431779157 CG42300 CG42300 - - - - 10178917 2197.50 0.2 0.39 0.963474123974886 Up 0.14446572447497 12798348 340.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 CG42878 CG42878 - - - - 43552 4955.00 9.055 3.305 -1.45406436944248 Down 0.640305111610091 CG7896 CG7896 K05401|1|9e-56|219|dme:Dmel_CG5195|toll-like recepto 3;K06838|4|3e-44|181|mcc:705901|slit 1 - GO:0005488//binding - 42465 670.00 21.265 19.76 -0.105897908041086 Down 0.221304979527143 CG17272 CG17272 K02183|1|6e-19|94.0|smm:Smp_026560.2|calmodulin - GO:0046872//metal ion binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0008152//metabolic process 42106 1011.92 54.445 26.11 -1.060197106325 Down 0.715163122440893 CG5840 Pyrroline-5-carboxylate reductase-like 2, isoform D K00286|1|5e-129|461|dme:Dmel_CG5840|pyrroline-5-carboxylate reductase [EC:1.5.1.2] - - - 35970 2573.80 77.91 93.46 0.262540522465236 Up 0.476225069343548 Pdk pyruvate dehydrogenase kinase, isoform D K00898|1|0.0|811|dya:Dyak_GE19277|pyruvate dehydrogenase kinase [EC:2.7.11.2] GO:0031980;GO:0031980 GO:0004673//protein histidine kinase activity;GO:0032559;GO:0004673//protein histidine kinase activity;GO:0032559 GO:0006468//protein phosphorylation;GO:0023060;GO:0032787//monocarboxylic acid metabolic process;GO:0006468//protein phosphorylation;GO:0023060;GO:0032787//monocarboxylic acid metabolic process 34405 1279.49 38.985 26.505 -0.556654593920584 Down 0.615869766213182 lft lowfat, isoform B - - - - 37343 782.00 2.37 1.9 -0.318887640567311 Down 0.193105270109629 CG13437 CG13437 - - - - 36683 1950.33 23.94 23.855 -0.00513146595919681 Down 0.0526350548144235 CG11807 CG11807, isoform C - - GO:0005543//phospholipid binding GO:0009987//cellular process 33819 12155.00 13.9 15.325 0.140802190967274 Up 0.245674283450007 bchs blue cheese K07295|1|6e-62|241|dpe:Dper_GL19043|nuclear receptor subfamily 2 group A;K12482|2|7e-13|78.6|oaa:100074143|RUN and FYVE domain-containing protein 1;K12182|3|2e-12|77.4|tad:TRIADDRAFT_20773|hepatocyte growth factor-regulated tyrosine kinase substrate - GO:0046914//transition metal ion binding - 12798293 251.00 0.01 0.215 4.4262647547021 Up 0.216153744551578 CG43182 CG43182 - - - - 43154 708.50 0.66 1.065 0.690315500867385 Up 0.200931184784044 Kaz-m1 Kazal-type protease inhibitor m1, isoform B K06254|1|7e-06|50.4|bfo:BRAFLDRAFT_118439|agrin - - - 5740672 3223.00 29.955 28.925 -0.0504798741702765 Down 0.137267203803989 CG34351 CG34351, isoform D - - - - 40469 1306.59 12.705 6.465 -0.9746741002431 Down 0.617983093382644 CG11438 CG11438, isoform B K01080|1|2e-154|545|dme:Dmel_CG11438|phosphatidate phosphatase [EC:3.1.3.4] GO:0044464//cell part GO:0016791//phosphatase activity GO:0008354//germ cell migration;GO:0006796//phosphate-containing compound metabolic process 317894 2064.00 12.88 8.08 -0.672705395362822 Down 0.556432439572051 CG32170 CG32170 - - - - 39587 1701.24 887.89 1009.395 0.18503798703661 Up 0.418868049134857 Mpcp mitochondrial phosphate carrier protein, isoform C K03454|1|1e-13|78.2|tad:TRIADDRAFT_25969|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part GO:0015103//inorganic anion transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0015698//inorganic anion transport;GO:0007450//dorsal/ventral pattern formation, imaginal disc 39992 661.00 2.165 2.295 0.0841271286870831 Up 0.0761127988376701 CG5506 CG5506 - - - - 53558 1991.77 19.305 11.365 -0.76437687012401 Down 0.620063399815084 wun2 wunen-2, isoform B K01080|1|5e-179|627|dme:Dmel_CG8805|phosphatidate phosphatase [EC:3.1.3.4] GO:0016020//membrane GO:0016791//phosphatase activity;GO:0022892 GO:0008354//germ cell migration;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process 41746 1384.00 2.085 1.555 -0.423132803314061 Down 0.215427288337076 spn-B spindle B K10880|1|1e-178|625|dme:Dmel_CG3325|DNA-repair protein XRCC3 - - - 39629 4251.17 3.905 4.15 0.0877887880923077 Up 0.101736890767402 Reck Reversion-inducing-cysteine-rich protein with kazal motifs, isoform B K06254|1|4e-10|68.2|oaa:100082599|agrin - - - 37769 529.48 20.805 21.68 0.0594344683091126 Up 0.145093118478404 Nxt1 NTF2-related export protein 1, isoform B - GO:0012505//endomembrane system;GO:0031981//nuclear lumen - GO:0006406//mRNA export from nucleus 33403 693.00 6.69 5.91 -0.178848080463928 Down 0.212092193897768 CG15387 CG15387 - - - - 5740142 426.00 5.16 5.06 -0.0282336807289439 Down 0.0618808611808216 Gpa2 glycoprotein hormone alpha 2 ortholog - - GO:0046983//protein dimerization activity - 14462487 380.00 10.51 32.4 1.62423114380981 Up 0.739367322678642 5740883 452.00 1.52 0.48 -1.66296501272243 Down 0.379342226918505 CG34248 CG34248, isoform B - - - - 5740411 642.00 0.21 0.72 1.77760757866355 Up 0.27304847444195 CG41562 CG41562 - - GO:0005488//binding - 33680 2387.00 2.755 3.76 0.44868034310648 Up 0.298375379738476 CG3225 CG3225 K13117|1|0.0|1296|dme:Dmel_CG3225|ATP-dependent RNA helicase DDX35 [EC:3.6.4.13] GO:0005681//spliceosomal complex GO:0004386//helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377 40924 3171.63 62.105 109.575 0.819137350959206 Up 0.70169066173557 CG2993 CG2993, isoform C K01277|1|2e-06|55.5|tca:661730|dipeptidyl-peptidase III [EC:3.4.14.4] - - - 42498 1816.00 13.32 12.55 -0.0859067182331278 Down 0.165499933958526 CG5745 CG5745 K13136|1|8e-11|68.9|nvi:100114269|gem associated protein 8 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0006909//phagocytosis;GO:0032318//regulation of Ras GTPase activity 326195 1548.00 0.64 0.855 0.417852514885898 Up 0.132380134724607 CG32086 CG32086, isoform B - - - - 32259 4326.00 2.45 2.3 -0.0911478880581956 Down 0.0813300752872804 CG43313 CG43313, isoform B K00747|1|0.0|1471|dme:Dmel_CG4351|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] GO:0000139//Golgi membrane GO:0016757//transferase activity, transferring glycosyl groups - 19835065 413.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 40437 2085.00 13.065 9.725 -0.425936969446467 Down 0.469125610883635 CG7442 CG7442 K08202|1|4e-75|282|isc:IscW_ISCW020957|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 19836087 2824.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 32288 2626.00 6.335 7.67 0.275881958362124 Up 0.305705983357549 CG15747 CG15747, isoform C K13206|1|5e-169|595|dme:Dmel_CG15747|coiled-coil domain-containing protein 55 - - - 2768911 765.00 0.115 0.195 0.761840262805236 Up 0.0923590014529124 CG13970 CG13970 - - - - 43412 2154.00 1.01 0.415 -1.28317205140487 Down 0.281435741645754 CG14527 CG14527 K01415|1|0.0|1390|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|3|5e-71|269|dgr:Dgri_GH24851|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37511 1805.74 31.33 23.91 -0.389930639659426 Down 0.531964073438119 Snp snipper, isoform G K01175|1|4e-32|139|nve:NEMVE_v1g82503| [EC:3.1.-.-];K13157|2|1e-27|124|dya:Dyak_GE12236|U11/U12 small nuclear ribonucleoprotein 65 kDa protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0004518//nuclease activity;GO:0005488//binding;GO:0004518//nuclease activity;GO:0005488//binding;GO:0004518//nuclease activity;GO:0005488//binding;GO:0004518//nuclease activity;GO:0005488//binding - 42683 714.00 7.32 5.81 -0.333305484879514 Down 0.336844538370096 Ccap crustacean cardioactive peptide, isoform B - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0008016//regulation of heart contraction 45928 3993.75 266.77 312.885 0.230036060764628 Up 0.461828028001585 shi shibire, isoform P K01528|1|0.0|1499|dme:Dmel_CG18102|dynamin GTPase [EC:3.6.5.5] GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0016020//membrane GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032561//guanyl ribonucleotide binding;GO:0003774//motor activity;GO:0015631//tubulin binding GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis;GO:0007613//memory;GO:0007424//open tracheal system development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0007635//chemosensory behavior;GO:0008049//male courtship behavior;GO:0008306//associative learning;GO:0034331;GO:0030036//actin cytoskeleton organization;GO:0002009//morphogenesis of an epithelium;GO:0030537//larval behavior;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007431//salivary gland development;GO:0043062//extracellular structure organization;GO:0048488//synaptic vesicle endocytosis 19835006 615.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 45368 2838.07 142.22 150.385 0.0805363126471178 Up 0.217936864350812 Treh trehalase, isoform G K01194|1|0.0|1063|dme:Dmel_CG9364|alpha,alpha-trehalase [EC:3.2.1.28] GO:0031225//anchored to membrane;GO:0031225//anchored to membrane;GO:0031225//anchored to membrane;GO:0031225//anchored to membrane;GO:0031225//anchored to membrane;GO:0031225//anchored to membrane GO:0015927//trehalase activity;GO:0015927//trehalase activity;GO:0015927//trehalase activity;GO:0015927//trehalase activity;GO:0015927//trehalase activity;GO:0015927//trehalase activity GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process;GO:0005984//disaccharide metabolic process 40196 3522.00 58.71 59.45 0.0180705532850581 Up 0.0865803724739136 CG14186 CG14186 - - - - 33242 904.00 0.09 0.055 -0.710493382805015 Down 0.0690133403777572 lectin-21Cb lectin-21Cb K06560|1|1e-06|53.1|tgu:100222908|mannose receptor, C type;K06563|5|3e-06|52.0|mmu:69142|CD209 antigen - - - 44326 738.00 32.875 35.505 0.111031312388744 Up 0.248580108308017 mRpL12 mitochondrial ribosomal protein L12 K13577|1|3e-07|55.1|tgu:100224946|mitochondrial dicarboxylate carrier GO:0000314//organellar small ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0040007//growth;GO:0006996//organelle organization 33800 1898.00 0.105 0.09 -0.222392421336448 Down 0.0521727644961036 CG11149 CG11149, isoform E K00741|1|0.0|978|dme:Dmel_CG11149|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149] - - GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior 36880 2419.56 3.135 1.645 -0.930377859066797 Down 0.407343811913882 resilin resilin, isoform B - - - - 31615 10423.37 7.81 8.99 0.202998567372468 Up 0.261392154272883 CG14438 CG14438, isoform C K09228|1|1e-09|67.8|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein;K09229|3|3e-07|59.7|bta:515564|KRAB and SCAN domains-containing zinc finger protein - - - 38398 681.00 221.735 228.565 0.0437679896407317 Up 0.137333245278035 CG17737 CG17737 K05286|1|4e-12|71.2|bmy:Bm1_04640|phosphatidylinositol glycan, class B [EC:2.4.1.-] - GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 39903 2489.59 39.58 27.93 -0.502956038767562 Down 0.596024303262449 CG6664 CG6664, isoform C K09288|1|0.0|662|dme:Dmel_CG6664|coiled-coil domain-containing protein 6 - - - 31358 1450.00 4.37 4.335 -0.0116012862787634 Down 0.0472856954167217 brn brainiac K02175|1|0.0|641|dme:Dmel_CG4934|putative enzyme (brainiac) GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008375//acetylglucosaminyltransferase activity GO:0001743//optic placode formation;GO:0016337//cell-cell adhesion;GO:0006687//glycosphingolipid metabolic process;GO:0007297//ovarian follicle cell migration;GO:0016334//establishment or maintenance of polarity of follicular epithelium;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006464//cellular protein modification process 31061 2159.00 0.02 0.025 0.321928094887362 Up 0.047219653942676 CG11384 CG11384 - - - - 14462709 1832.00 5.435 5.31 -0.0335681742231555 Down 0.0651829348831066 39965 4030.78 35.03 42.46 0.277513383103315 Up 0.467837802139744 CG7510 CG7510, isoform B - GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0023033 47285 2996.00 14.53 16.275 0.163622840420156 Up 0.275525029718663 repo reversed polarity K09332|1|5e-22|107|dre:30473|retina and anterior neural fold homeobox protein;K09452|3|3e-21|104|dre:30657|homeobox protein aristaless-related GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-dependent 19834744 505.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 31629 3240.00 12.22 14.43 0.239827014672469 Up 0.345892220314357 CG4557 CG4557 K10352|1|3e-08|61.6|hsa:8735|myosin heavy chain - - - 5740590 5011.66 18.715 23.44 0.324777521522286 Up 0.465427288337076 CG34353 CG34353, isoform C K06772|1|5e-26|119|dre:664692|limbic system-associated membrane protein;K06775|5|6e-26|119|mdo:100016404|neuronal growth regulator 1 - - - 38656 818.00 1.325 0.75 -0.821029858954681 Down 0.252179368643508 mad2 mad2 K02537|1|2e-115|415|dme:Dmel_CG17498|mitotic spindle assembly checkpoint protein MAD2 GO:0043231//intracellular membrane-bounded organelle;GO:0005876//spindle microtubule;GO:0000775//chromosome, centromeric region;GO:0012505//endomembrane system - GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition 19835268 739.00 3.06 2.93 -0.0626309882704037 Down 0.0735041606128649 38715 4157.00 2.525 2.325 -0.119052671643763 Down 0.0991942940166425 CG7376 CG7376, isoform B K10875|1|9e-11|70.1|dgr:Dgri_GH10642|DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.1.-] - GO:0017111//nucleoside-triphosphatase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0032559 - 41124 1841.00 7.28 11.675 0.681412194398328 Up 0.547318716153745 betaTub85D beta-Tubulin at 85D K07375|1|0.0|837|dvi:Dvir_GJ23573|tubulin beta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity;GO:0042287//MHC protein binding GO:0001909//leukocyte mediated cytotoxicity;GO:0043623//cellular protein complex assembly;GO:0009207;GO:0007017//microtubule-based process;GO:0007431//salivary gland development 33447 1234.00 0.13 0.42 1.69187770463767 Up 0.19961035530313 CG15395 CG15395 - GO:0005819//spindle - GO:0007051//spindle organization;GO:0045132//meiotic chromosome segregation 45775 22681.46 11.39 15.625 0.4560884427287 Up 0.504788006868313 mei-P26 mei-P26, isoform E K11997|1|3e-50|201|phu:Phum_PHUM061260|tripartite motif-containing protein 2/3 GO:0044464//cell part GO:0046914//transition metal ion binding GO:0022403;GO:0019953//sexual reproduction 32592 1178.61 223.165 131.93 -0.758338119264975 Down 0.703407740060758 CG9914 CG9914, isoform B K13247|1|2e-168|591|dme:Dmel_CG9914|L-gulonate 3-dehydrogenase [EC:1.1.1.45] - GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0032787//monocarboxylic acid metabolic process 42851 687.21 19.56 20.27 0.0514397185146649 Up 0.127360982697134 CG6000 CG6000, isoform D K01010|1|4e-21|100|dme:Dmel_CG12279|thiosulfate sulfurtransferase [EC:2.8.1.1] - - - 3772179 605.16 56.97 51.23 -0.15321351441609 Down 0.327763835688813 primo-1 primo-1, isoform B K01078|1|2e-90|333|dme:Dmel_CG33747|acid phosphatase [EC:3.1.3.2];K01104|1|2e-90|333|dme:Dmel_CG33747|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 34814 1478.00 6.16 7.065 0.197759209639038 Up 0.232730154537049 nimB4 nimrod B4 K06252|1|2e-21|103|oaa:100076692|tenascin - - GO:0007166//cell surface receptor signaling pathway 19835762 351.00 0.125 0.44 1.81557542886257 Up 0.212884691586316 41866 583.00 9.265 7.535 -0.298183464429442 Down 0.345595033681152 CG6196 TRAPP subunit 33 ortholog - - - - 33437 1511.00 0.365 0.4 0.132103536007345 Up 0.0577532690529653 CG3515 CG3515 K08870|1|3e-48|192|dre:321614|PTK9 protein tyrosine kinase 9;K11804|2|5e-11|69.3|xla:431952|WD repeat-containing protein 42A;K11800|4|4e-10|66.2|xla:100036835|WD repeat-containing protein 22 - - - 34787 3003.00 67.165 61.765 -0.120920087215086 Down 0.282228239334302 adat adat, isoform B K01672|1|1e-155|551|dme:Dmel_CG7820|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0004000//adenosine deaminase activity;GO:0016836//hydro-lyase activity GO:0008033//tRNA processing 32889 6101.38 3.825 4.01 0.0681424888749059 Up 0.0841698586712455 CG43759 CG43759, isoform D - - - - 19836216 832.00 0.055 0.11 1 Up 0.0856557918372738 38079 3244.00 3.605 4.195 0.218671551199001 Up 0.194492141064589 Rev1 Rev1 K03515|1|0.0|1938|dme:Dmel_CG12189|DNA repair protein REV1 [EC:2.7.7.-] GO:0044464//cell part GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0034061 GO:0006301//postreplication repair 59253 653.04 20.295 23.78 0.228624375047962 Up 0.381158367454762 CG18508 CG18508, isoform B - - - - 33840 3044.10 4.5 8.11 0.849776913000236 Up 0.541738211596883 CG9098 CG9098, isoform C K08889|1|3e-12|74.7|tgu:100222117|fer (fps/fes related) tyrosine kinase [EC:2.7.10.2] GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction 33215 556.00 16.315 11.68 -0.482158713211847 Down 0.518854840840048 CG11885 CG11885 - - - - 2769008 7640.09 14.85 21.12 0.508146903670325 Up 0.557125875049531 Dscam4 down syndrome cell adhesion molecule 4, isoform J K06767|1|0.0|922|xtr:100216449|Down syndrome cell adhesion molecule - - - 14462617 676.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG43668 CG43668 - - - - 39396 1021.47 172.545 112.065 -0.622636900249045 Down 0.67250033020737 Adk1 adenylate kinase-1, isoform B K00939|1|5e-102|371|dme:Dmel_CG17146|adenylate kinase [EC:2.7.4.3] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016301//kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559;GO:0016301//kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559 GO:0009205;GO:0009205 42412 3663.05 40.1 46.715 0.220283631261471 Up 0.41091005151235 CG42668 CG42668, isoform N - - - GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process 32198 1326.00 28.705 6.05 -2.24629500810931 Down 0.762547880068683 Cpr11A cuticular protein 11A - - GO:0042302//structural constituent of cuticle - 40654 621.00 531.99 516.12 -0.0436925900273976 Down 0.139677717606657 RpL35A ribosomal protein L35A K02917|1|3e-63|241|dya:Dyak_GE25280|large subunit ribosomal protein L35Ae GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 39374 1513.00 12.305 13.145 0.0952694841598859 Up 0.177684585919958 l(3)j2D3 lethal (3) j2D3 - - - - 40330 4505.94 12.26 10.315 -0.249215157804297 Down 0.336382248051777 ko knockout, isoform B - - - - 36217 911.00 0.22 0.24 0.125530882083859 Up 0.0491348566900013 etaTry etaTrypsin K01312|1|1e-143|508|dme:Dmel_CG12386|trypsin [EC:3.4.21.4] GO:0044421//extracellular region part GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40607 3208.00 9.29 9.48 0.0292084625156064 Up 0.0753203011491217 Gnf1 germ line transcription factor 1, isoform B K10754|1|0.0|1652|dme:Dmel_CG1119|replication factor C subunit 1 GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0003677//DNA binding;GO:0016462//pyrophosphatase activity;GO:0032559;GO:0003677//DNA binding;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process 46201 2916.00 4.725 4.5 -0.0703893278913979 Down 0.0912693171311584 l(3)07882 lethal (3) 07882 - GO:0031981//nuclear lumen GO:0003723//RNA binding GO:0006364//rRNA processing 3354919 1431.03 65.44 58.89 -0.152150074754422 Down 0.331197992339189 Dbp80 dead box protein 80, isoform G K01529|1|3e-34|144|gga:426504| [EC:3.6.1.-];K13025|4|2e-11|69.3|nve:NEMVE_v1g236387|translation initiation factor eIF-4A 3 [EC:3.6.1.-] - GO:0032559;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0042623//ATPase activity, coupled - 40902 1836.00 0.31 0.61 0.976541027176011 Up 0.185510500594373 alpha-Est6 alpha-Esterase-6 K01044|1|0.0|1150|dme:Dmel_CG1108|carboxylesterase [EC:3.1.1.1];K03927|3|9e-133|474|dan:Dana_GF17295|carboxylesterase type B [EC:3.1.1.1] - GO:0016788//hydrolase activity, acting on ester bonds - 35492 2426.39 36.41 37.94 0.0593849379669608 Up 0.161471404041738 CG10417 CG10417, isoform B K01090|1|0.0|1102|dme:Dmel_CG10417|protein phosphatase [EC:3.1.3.16] GO:0043234//protein complex;GO:0043234//protein complex GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 32312 5379.37 8.615 9.415 0.12811029838928 Up 0.193765684850086 Tango13 transport and golgi organization 13, isoform G K01021|1|0.0|756|dya:Dyak_GE17090|protein-tyrosine sulfotransferase [EC:2.8.2.20] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008146//sulfotransferase activity;GO:0008146//sulfotransferase activity - 34885 2479.02 115.78 132.73 0.197108427790015 Up 0.416919825650509 vig vasa intronic gene, isoform D K13199|1|1e-140|500|dme:Dmel_CG4170|plasminogen activator inhibitor 1 RNA-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome - GO:0034968//histone lysine methylation;GO:0035194//posttranscriptional gene silencing by RNA;GO:0034968//histone lysine methylation;GO:0035194//posttranscriptional gene silencing by RNA;GO:0034968//histone lysine methylation;GO:0035194//posttranscriptional gene silencing by RNA;GO:0034968//histone lysine methylation;GO:0035194//posttranscriptional gene silencing by RNA 34242 9757.88 10.33 10.95 0.0840906156234761 Up 0.146645093118478 tai taiman, isoform H K11255|1|8e-11|71.2|tca:656017|nuclear receptor coactivator 2 - - - 43014 2680.00 41.395 43.85 0.083120323999414 Up 0.201162329943204 CG13650 CG13650 K01415|1|4e-14|80.5|dre:777750|endothelin-converting enzyme [EC:3.4.24.71] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33908 1105.00 47.805 38.065 -0.328696441634779 Down 0.518458591995773 epsilonCOP coat protein (coatomer) epsilon - GO:0030120//vesicle coat;GO:0015630//microtubule cytoskeleton GO:0005488//binding GO:0048193//Golgi vesicle transport 41488 1777.00 0.07 0.1 0.514573172829758 Up 0.0619138819178444 Cyp313a3 Cyp313a3 K00517|1|0.0|964|dme:Dmel_CG10093| [EC:1.14.-.-] - - - 42254 1921.00 7.1 7.315 0.0430388397464425 Up 0.0819904900277374 CG7718 CG7718 K00995|1|0.0|967|dme:Dmel_CG7718|CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] - GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006644//phospholipid metabolic process 42766 1020.00 0.605 0.725 0.26104585274034 Up 0.0930524369303923 CG17380 CG17380 K03909|1|1e-09|63.9|mcc:613026|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 246388 965.00 8.935 23.94 1.42188351790201 Up 0.711695945053494 CG30008 CG30008 K00680|1|8e-31|134|dme:Dmel_CG8534| [EC:2.3.1.-];K10249|2|5e-29|128|isc:IscW_ISCW017283|elongation of very long chain fatty acids protein 4;K10247|5|6e-27|121|dre:406725|elongation of very long chain fatty acids protein 1 GO:0031224//intrinsic to membrane - - 8674077 1115.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 fdy flagrante delicto Y K13199|1|3e-128|457|dsi:Dsim_GD21176|plasminogen activator inhibitor 1 RNA-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0031332;GO:0005700//polytene chromosome - GO:0034968//histone lysine methylation;GO:0035194//posttranscriptional gene silencing by RNA 42903 3359.96 15.545 22.635 0.542104689906775 Up 0.57518821820103 CG5746 CG5746, isoform G - - - - 3772382 6081.97 22.315 21.795 -0.0340166028978576 Down 0.0974111742174085 cp309 cp309, isoform P K11499|1|1e-23|114|spu:592172|centromere protein F;K09291|5|8e-23|111|dre:558883|nucleoprotein TPR GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center GO:0004930//G-protein coupled receptor activity;GO:0005488//binding;GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0048870//cell motility;GO:0007606//sensory perception of chemical stimulus;GO:0000226//microtubule cytoskeleton organization;GO:0048870//cell motility;GO:0007606//sensory perception of chemical stimulus;GO:0000226//microtubule cytoskeleton organization 32821 2017.90 485.415 418.015 -0.215663977734842 Down 0.453209615638621 Tsf1 transferrin 1, isoform C K06569|1|6e-23|109|tgu:100223073|melanoma-associated antigen p97 - GO:0015082;GO:0005506//iron ion binding GO:0030005;GO:0006950//response to stress;GO:0000041//transition metal ion transport 36108 701.00 12.445 12.01 -0.0513300792754017 Down 0.111742174085326 CG11777 CG11777 K12734|1|1e-92|338|dya:Dyak_GE19364|peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8] - GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 5740805 380.00 13.505 13.255 -0.0269569696417081 Down 0.081197992339189 CG34208 CG34208 - - - - 31701 1518.00 13.075 11.325 -0.207299896200706 Down 0.30630035662396 bys by S6 - - - - 40297 1849.00 0.69 0.835 0.275179835695883 Up 0.103586052040682 Six4 Six4, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0048513//organ development;GO:0045137//development of primary sexual characteristics;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0048513//organ development;GO:0045137//development of primary sexual characteristics;GO:0006351//transcription, DNA-dependent 38284 4114.94 0.52 0.99 0.928916901938517 Up 0.23494254391758 ACXD ACXD, isoform B K01768|1|0.0|2282|dme:Dmel_CG5712|adenylate cyclase [EC:4.6.1.1] GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process 41117 1556.67 8.185 6.46 -0.341448251780229 Down 0.357548540483424 CG8129 CG8129, isoform B K01754|1|0.0|639|dme:Dmel_CG8129|threonine dehydratase [EC:4.3.1.19] - GO:0048037//cofactor binding;GO:0016841//ammonia-lyase activity;GO:0031406//carboxylic acid binding;GO:0048037//cofactor binding;GO:0016841//ammonia-lyase activity;GO:0031406//carboxylic acid binding - 10178835 626.00 1.03 1.325 0.363348022267343 Up 0.156353189803196 CG42766 CG42766, isoform B - - - - 3772414 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 34262 1333.00 0.29 0.345 0.250543461650597 Up 0.0674943864747061 CG3769 CG3769 K10417|1|0.0|739|dme:Dmel_CG3769|dynein light intermediate chain 2, cytosolic - - - 39866 8219.57 21.065 23.76 0.173686920238511 Up 0.316866992471272 Dab disabled, isoform I K12475|1|3e-40|168|cin:100177528|disabled homolog 2 GO:0044424//intracellular part;GO:0044424//intracellular part GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0001751//compound eye photoreceptor cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 40697 2421.00 34.345 33.615 -0.0309949349104895 Down 0.102661471404042 CG2182 CG2182 - - - - 35774 2412.00 12.585 8.24 -0.610988973977761 Down 0.537016246202615 sut1 sugar transporter 1 K07299|1|1e-77|291|rno:24778|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity GO:0006810//transport 249072 5385.84 17.165 19.13 0.156367016388856 Up 0.284935939770176 Liprin-alpha Liprin-alpha, isoform E K10352|1|3e-16|88.6|oaa:100086990|myosin heavy chain - - GO:0007411//axon guidance;GO:0042051//compound eye photoreceptor development;GO:0048489//synaptic vesicle transport;GO:0030516//regulation of axon extension;GO:0007154//cell communication;GO:0007411//axon guidance;GO:0042051//compound eye photoreceptor development;GO:0048489//synaptic vesicle transport;GO:0030516//regulation of axon extension;GO:0007154//cell communication 42126 2125.36 0.83 1.525 0.877626001103324 Up 0.285200105666358 ald altered disjunction, isoform B K08866|1|0.0|1137|dme:Dmel_CG7643|serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1] - - - 33687 1734.00 8.05 7.725 -0.0594538502102426 Down 0.105666358473121 CG11927 CG11927 - - - - 40692 1424.00 19.82 20.33 0.0366532526582441 Up 0.108274996697926 CG12170 CG12170 K09458|1|0.0|827|dme:Dmel_CG12170|3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] - GO:0016301//kinase activity;GO:0016746//transferase activity, transferring acyl groups;GO:0032559 GO:0006464//cellular protein modification process;GO:0006631//fatty acid metabolic process 35429 2020.00 0.135 0.19 0.493040011280117 Up 0.0743296790384361 CG11630 CG11630 - - - - 37440 883.00 0.225 0.68 1.59560974492066 Up 0.25567956676793 CG9822 CG9822 K02330|1|2e-11|69.3|tca:656359|DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-];K00747|3|3e-07|55.5|tca:656110|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] - - - 31262 3502.00 0.155 0.26 0.746243407754217 Up 0.100977413815876 fs(1)Yb female sterile (1) Yb - - - - 42568 1450.00 0.11 0.065 -0.758991900496205 Down 0.0760797781006472 Gr93a gustatory receptor 93a K08471|1|0.0|723|dme:Dmel_CG13417|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33366 1309.00 0.065 0.65 3.32192809488736 Up 0.325452384097213 CG15358 CG15358 K05328|1|5e-15|82.0|dan:Dana_GF15877|transient receptor potential cation channel subfamily C, invertebrate;K06563|2|2e-14|79.7|mmu:170780|CD209 antigen - - - 42220 936.80 7.635 8.355 0.130011671264337 Up 0.185543521331396 CG7685 CG7685, isoform B K01187|1|5e-115|413|dme:Dmel_CG7685|alpha-glucosidase [EC:3.2.1.20];K08288|2|3e-23|108|rno:300445|protein kinase C substrate 80K-H GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0051259//protein oligomerization 318947 751.00 29.72 28.24 -0.073694027267416 Down 0.173061682736759 CG31800 CG31800 - - - - 41138 2300.29 35.55 37.05 0.0596239826864185 Up 0.160844010038304 rump rumpelstiltskin, isoform B K12887|1|9e-18|92.4|dre:555643|heterogeneous nuclear ribonucleoprotein M GO:0043231//intracellular membrane-bounded organelle GO:0003729//mRNA binding GO:0006403//RNA localization;GO:0000578//embryonic axis specification 35813 5147.99 15.785 18.435 0.223893155780833 Up 0.353090740985339 pdm3 pou domain motif 3, isoform F K09368|1|5e-65|250|tgu:100219064|POU domain transcription factor, class 6 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 42699 2267.00 3.875 5.645 0.542777270611401 Up 0.398098005547484 CG4725 CG4725 K01415|1|1e-42|174|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|2e-37|157|dvi:Dvir_GJ16677|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 12798207 1752.27 4.625 1.085 -2.0917583229592 Down 0.604411570466253 CG43064 CG43064, isoform B - - - - 31739 1064.33 8.795 8.57 -0.037388373359461 Down 0.0830141328754458 CG17982 CG17982, isoform B - - - - 43164 1248.00 43.55 34.815 -0.322963695420588 Down 0.507000396248844 vps2 vacuolar protein sorting 2 K12191|1|7e-72|271|dsi:Dsim_GD21266|charged multivesicular body protein 2A - - GO:0006810//transport 36497 2473.87 29.175 28.75 -0.0211706998756105 Down 0.0812310130762119 drk downstream of receptor kinase, isoform F K04364|1|1e-120|434|dvi:Dvir_GJ19679|growth factor receptor-binding protein 2 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0030674//protein binding, bridging;GO:0004871//signal transducer activity;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0004871//signal transducer activity;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0004871//signal transducer activity;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0004871//signal transducer activity;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0004871//signal transducer activity;GO:0005102//receptor binding GO:0065008;GO:0007472//wing disc morphogenesis;GO:0007613//memory;GO:0007264//small GTPase mediated signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0000578//embryonic axis specification;GO:0009792//embryo development ending in birth or egg hatching;GO:0008306//associative learning;GO:0065008;GO:0007472//wing disc morphogenesis;GO:0007613//memory;GO:0007264//small GTPase mediated signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0000578//embryonic axis specification;GO:0009792//embryo development ending in birth or egg hatching;GO:0008306//associative learning;GO:0065008;GO:0007472//wing disc morphogenesis;GO:0007613//memory;GO:0007264//small GTPase mediated signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0000578//embryonic axis specification;GO:0009792//embryo development ending in birth or egg hatching;GO:0008306//associative learning;GO:0065008;GO:0007472//wing disc morphogenesis;GO:0007613//memory;GO:0007264//small GTPase mediated signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0000578//embryonic axis specification;GO:0009792//embryo development ending in birth or egg hatching;GO:0008306//associative learning;GO:0065008;GO:0007472//wing disc morphogenesis;GO:0007613//memory;GO:0007264//small GTPase mediated signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0000578//embryonic axis specification;GO:0009792//embryo development ending in birth or egg hatching;GO:0008306//associative learning 38374 1477.00 15.87 13.08 -0.278939587337099 Down 0.393442081627262 CG1291 CG1291 K03843|1|0.0|846|dme:Dmel_CG1291|alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.-] GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0016757//transferase activity, transferring glycosyl groups GO:0008152//metabolic process 36406 740.00 17.93 20.325 0.180879864094015 Up 0.315810328886541 mRpL18 mitochondrial ribosomal protein L18 - GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 38805 1008.00 2.11 2.615 0.309567947539756 Up 0.199082023510765 CG8607 CG8607 K06971|1|7e-148|523|dme:Dmel_CG8607| - - - 12798124 564.00 0.36 0.085 -2.08246216019197 Down 0.197232862237485 CG43195 CG43195, isoform B - - - - 35719 1305.00 5.875 3.585 -0.712615732750457 Down 0.459252410513803 CG1942 CG1942 K11172|1|2e-52|206|mcc:694889|diacylglycerol O-acyltransferase 2-like protein 6 [EC:2.3.1.-];K11160|3|3e-51|202|mdo:100011089|diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.76] - GO:0016746//transferase activity, transferring acyl groups - 32102 1002.00 3.665 2.395 -0.613787542397632 Down 0.35322282393343 Kmn1 kinetochore Mis12-Ndc80 network component 1 - GO:0000776//kinetochore - GO:0000070//mitotic sister chromatid segregation 39219 698.41 14.425 12.175 -0.24464954656314 Down 0.347972526746797 blos4 biogenesis of lysosome-related organelles complex 1, subunit 4, isoform B K08366|1|2e-49|196|dpo:Dpse_GA12789|cappuccino - - - 39540 4327.10 23.1 17.72 -0.382514247748402 Down 0.504193633601902 ssp2 short spindle 2, isoform C - - - - 40200 1669.66 16.095 12.825 -0.327653750983262 Down 0.434916127327962 CG7365 CG7365, isoform B K06269|1|3e-30|133|tgu:100232535|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process;GO:0006909//phagocytosis 40876 3103.00 138.725 161.62 0.22037793541905 Up 0.44416193369436 Syt4 synaptotagmin 4 K01104|1|7e-50|199|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|2|2e-19|98.6|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10];K02677|3|2e-13|78.6|nve:NEMVE_v1g93932|classical protein kinase C [EC:2.7.11.13];K03008|4|2e-13|78.6|gga:417513|DNA-directed RNA polymerase II subunit J GO:0030136//clathrin-coated vesicle GO:0004175//endopeptidase activity;GO:0005543//phospholipid binding;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0019538//protein metabolic process;GO:0001505//regulation of neurotransmitter levels 12798337 704.00 0.455 0.45 -0.0159415438690215 Down 0.0413749834896315 43544 862.00 5.915 47.085 2.99281745596348 Up 0.802734117025492 Jon99Cii jonah 99Cii K01310|1|3e-129|461|dme:Dmel_CG31362|chymotrypsin [EC:3.4.21.1];K01362|2|3e-129|461|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0032501//multicellular organismal process;GO:0019538//protein metabolic process 35150 1921.00 8.735 7.97 -0.132227978926288 Down 0.190331528199709 CG10428 CG10428 - - GO:0016741 - 19835967 353.00 1.54 1.045 -0.559427408614019 Down 0.217276449610355 35422 2785.67 973.11 996.015 0.0335645735182682 Up 0.117487782327302 Ef2b elongation factor 2, isoform D K03234|1|0.0|1625|dme:Dmel_CG2238|elongation factor EF-2 [EC:3.6.5.3] GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding GO:0006412//translation;GO:0007052//mitotic spindle organization;GO:0006412//translation;GO:0007052//mitotic spindle organization;GO:0006412//translation;GO:0007052//mitotic spindle organization 117365 2265.13 11.78 12.865 0.127111917903339 Up 0.217243428873332 HBS1 HBS1, isoform B K03267|1|3e-91|336|nve:NEMVE_v1g85083|G1 to S phase transition protein GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0008079//translation termination factor activity - 38976 3566.28 22.765 20.425 -0.156481380986153 Down 0.297582882049927 foi fear-of-intimacy, isoform D K10085|1|3e-06|55.1|bmy:Bm1_26630|ER degradation enhancer, mannosidase alpha-like 2 GO:0044464//cell part GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport 42561 3975.14 49.355 56.72 0.20066128558968 Up 0.395720512481839 GABA-B-R2 metabotropic GABA-B receptor subtype 2, isoform C K04616|1|0.0|2316|dme:Dmel_CG6706|gamma-aminobutyric acid (GABA) B receptor 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0008066//glutamate receptor activity GO:0007635//chemosensory behavior;GO:0023060;GO:0031339//negative regulation of vesicle fusion;GO:0007166//cell surface receptor signaling pathway;GO:0007635//chemosensory behavior;GO:0023060;GO:0031339//negative regulation of vesicle fusion;GO:0007166//cell surface receptor signaling pathway 31646 2452.27 91.34 68.33 -0.418727662903716 Down 0.593613789459781 Inx2 innexin 2, isoform D - GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane GO:0022829//wide pore channel activity GO:0007635//chemosensory behavior;GO:0002009//morphogenesis of an epithelium 2768831 938.23 468.605 387.69 -0.273468824816579 Down 0.505976753401136 CG33470 CG33470, isoform C K01137|1|1e-20|100|dse:Dsec_GM20282|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14] - - - 36160 832.71 13.29 13.62 0.0353855987358968 Up 0.0959582617884031 Rpb5 Rpb5, isoform B K03013|1|1e-116|419|dya:Dyak_GE13062|DNA-directed RNA polymerase II subunit E GO:0043231//intracellular membrane-bounded organelle GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 41857 2401.57 17.09 18.28 0.0971136733819306 Up 0.198355567296262 CG6236 CG6236, isoform B - - - - 36549 1234.00 1.245 2.38 0.934815831239862 Up 0.360850614185709 CG18568 CG18568, isoform B - - - - 31716 4858.06 37.305 36.71 -0.0231958938385157 Down 0.0845330867784969 sws swiss cheese, isoform C K07001|1|1e-180|632|dse:Dsec_GM11957| - - - 38553 1126.00 1.205 0.01 -6.91288933622996 Down 0.545469554880465 CG7465 CG7465 - - - - 40391 8056.69 21.52 24.39 0.18061168023956 Up 0.329381851802932 Wnk WNK homolog, isoform K K08867|1|0.0|1628|dme:Dmel_CG7177|WNK lysine deficient protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 36937 1567.47 105.115 84.29 -0.318535169874508 Down 0.536917183991547 CG11395 CG11395, isoform B K10858|1|3e-09|63.5|cin:100180400|DNA mismatch repair protein PMS2;K12464|4|1e-07|58.2|rno:84469|melanoma-associated antigen D1 - - - 40600 1228.00 0.415 0.56 0.432315490710679 Up 0.113096024303262 CG1126 CG1126 - GO:0044464//cell part - GO:0032401//establishment of melanosome localization;GO:0006810//transport;GO:0010927 37256 752.00 0.995 1.52 0.611302892899936 Up 0.226687359661868 CG15124 CG15124 - - - - 43938 615.86 115.675 121.875 0.0753251199590395 Up 0.215031039492801 cl clot, isoform C K00771|1|3e-15|81.3|smm:Smp_128310.1|protein xylosyltransferase [EC:2.4.2.26] - - GO:0042441//eye pigment metabolic process 41949 957.86 24.68 13.285 -0.893544166658911 Down 0.659225993924184 CG10407 CG10407, isoform B - - - - 37641 5318.44 43.6 31.05 -0.489734866556445 Down 0.597014925373134 nahoda nahoda, isoform C K06568|1|5e-48|194|cel:C09F9.2|mucin 1, transmembrane - GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0006547//histidine metabolic process;GO:0006547//histidine metabolic process 43824 3770.00 192.145 214.615 0.159555478265721 Up 0.366232994320433 Cals Calsyntenin-1, isoform D K04601|1|5e-09|64.3|hsa:1952|cadherin EGF LAG seven-pass G-type receptor 2 (flamingo) - - - 34154 1230.00 6.77 8.65 0.35354429894909 Up 0.372110685510501 CG13390 CG13390 K03979|1|0.0|714|dme:Dmel_CG13390|GTP-binding protein GO:0005622//intracellular GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding;GO:0032561//guanyl ribonucleotide binding - 19835554 409.00 0.855 0.01 -6.4178525148859 Down 0.466682076343944 38628 1380.00 27.485 30.69 0.159124166428724 Up 0.316800950997226 bc10 bc10 - GO:0016020//membrane - GO:0009987//cellular process 42477 4416.00 8.995 10.46 0.217687664995459 Up 0.292332584863294 CG31191 CG31191, isoform D - - - - 32710 612.00 167.965 33.535 -2.32442113305903 Down 0.80062078985603 CG12998 CG12998, isoform B - - - - 19835163 1232.00 0.485 0.735 0.599759502649237 Up 0.151829348831066 318035 2099.87 3.255 3.705 0.186815999140198 Up 0.163980980055475 CG32452 CG32452, isoform C - - - - 14462680 492.00 5.07 4.535 -0.160883196474818 Down 0.172632413155462 39693 4903.52 16.86 19.05 0.176186461438602 Up 0.308644828952582 RhoGAP71E Rho GTPase activating protein at 71E, isoform G K10360|1|1e-07|59.7|gga:420135|myosin IX GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - GO:0023060;GO:0023060;GO:0023060;GO:0023060;GO:0023060 40551 3345.33 58.67 62.74 0.0967625371722378 Up 0.244947827235504 CG1090 CG1090, isoform I K13752|1|5e-81|303|dre:550467|solute carrier family 24 (sodium/potassium/calcium exchanger), member 4;K13750|3|4e-72|273|cfa:481554|solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport 50434 821.00 0.29 0.325 0.164386817900883 Up 0.0596684718002906 CG32983 CG32983 - - - - 37577 2523.00 1.35 5.225 1.95247162991741 Up 0.611940298507463 nsr putative spermatogenesis regulator, isoform B K13198|1|5e-38|156|mdo:100025483|KH domain-containing, RNA-binding, signal transduction-associated protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0012501//programmed cell death 38199 3977.80 28.8 26.005 -0.147279773733474 Down 0.299663188482367 alphaCop coat protein (coatomer) alpha, isoform B K05236|1|0.0|2302|dme:Dmel_CG7961|coatomer protein complex, subunit alpha (xenin) GO:0030120//vesicle coat;GO:0042598;GO:0044421//extracellular region part;GO:0030120//vesicle coat;GO:0042598;GO:0044421//extracellular region part GO:0005515//protein binding;GO:0005515//protein binding GO:0006909//phagocytosis;GO:0007589//body fluid secretion;GO:0019915//lipid storage;GO:0048200;GO:0015031//protein transport;GO:0006909//phagocytosis;GO:0007589//body fluid secretion;GO:0019915//lipid storage;GO:0048200;GO:0015031//protein transport 3772188 764.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 CG33648 CG33648, isoform C K09255|1|2e-16|84.7|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|1e-08|58.9|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 36343 2733.01 0.02 0.035 0.807354922057604 Up 0.0552767137762515 CG13160 CG13160, isoform B - - GO:0016787//hydrolase activity GO:0019538//protein metabolic process;GO:0006810//transport 19835806 317.00 1.265 1.88 0.571595276983327 Up 0.245773345661075 2768871 5028.00 0.03 0.145 2.27301849440642 Up 0.126832650904768 CG33235 CG33235 - - - - 40356 1391.57 59.395 55.075 -0.108943897012022 Down 0.262547880068683 CG11309 CG11309, isoform F K01175|1|6e-33|142|mmu:68607| [EC:3.1.-.-];K13703|2|1e-07|58.2|nvi:100122014|abhydrolase domain-containing protein 11 - - - 41465 2384.00 1.755 2.875 0.712090925527177 Up 0.341665565975433 ssp5 short spindle 5 - - - - 19834786 545.00 4.675 1.81 -1.36897666769179 Down 0.543752476555277 41558 2464.00 2.455 1.005 -1.28852752313576 Down 0.423953242636376 CG6234 Dpp target gene - - - - 37928 1497.00 1.38 1.65 0.257797757467646 Up 0.134592524105138 CG4681 CG4681 K10352|1|2e-08|60.5|bta:281338|myosin heavy chain - - - 38089 984.76 2.795 4.37 0.644784996657408 Up 0.390239070136045 CG13896 CG13896, isoform C - - - - 12798072 1790.91 5.045 4.83 -0.0628310802705841 Down 0.088033284902919 42209 1211.00 5.405 5.855 0.115374552766565 Up 0.146182802800158 Nup43 nucleoporin 43kD - - - - 53586 3504.88 11.965 11.945 -0.00241354308216661 Down 0.0416061286487914 Dhap-at dihydroxyacetone phosphate acyltransferase, isoform C K00649|1|0.0|1337|dme:Dmel_CG4625|glyceronephosphate O-acyltransferase [EC:2.3.1.42] GO:0042579//microbody GO:0016413//O-acetyltransferase activity - 42915 825.00 0.05 0.12 1.26303440583379 Up 0.0926561880861181 CG5768 CG5768, isoform D - - - - 5740430 398.00 2.07 1.195 -0.792620149518577 Down 0.311088363492273 CG34299 CG34299, isoform B - - - - 14462518 454.00 29.83 24.38 -0.291065851715 Down 0.45713908334434 43588 1222.04 28.09 29.645 0.0777321722634043 Up 0.187194558182539 CG1983 CG1983, isoform B K06997|1|2e-146|518|dsi:Dsim_GD17245| GO:0043231//intracellular membrane-bounded organelle - - 38597 1583.72 5.04 2.81 -0.84285360327899 Down 0.46721040813631 CG4623 CG4623, isoform C - - - - 39533 9385.67 22.69 28.27 0.317215274158838 Up 0.479097873464536 dysc dyschronic, isoform J K06112|1|9e-12|73.2|ssc:100153223|membrane-associated guanylate kinase-related;K08018|5|2e-10|68.6|bfo:BRAFLDRAFT_131151|Rap guanine nucleotide exchange factor (GEF) 2 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 50286 452.56 4451.7 4085.98 -0.123674230353149 Down 0.30630035662396 Nplp2 Neuropeptide-like precursor 2, isoform B - GO:0044421//extracellular region part GO:0005179//hormone activity - 37153 761.00 0.11 0.245 1.15527822547791 Up 0.127228899749042 CG15071 CG15071 - - - - 32057 3705.59 40.77 49.24 0.27232280499591 Up 0.46536124686303 Dlic dynein light intermediate chain, isoform D K10416|1|0.0|875|dme:Dmel_CG1938|dynein light intermediate chain 1, cytosolic GO:0030286//dynein complex;GO:0030286//dynein complex;GO:0030286//dynein complex GO:0016887//ATPase activity;GO:0016887//ATPase activity;GO:0016887//ATPase activity GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0048812//neuron projection morphogenesis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010970//microtubule-based transport;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0048812//neuron projection morphogenesis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010970//microtubule-based transport;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0048812//neuron projection morphogenesis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010970//microtubule-based transport 32360 1084.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 betaNACtes1 betaNACtes1 K01527|1|1e-08|60.1|aga:AgaP_AGAP006614|nascent polypeptide-associated complex subunit beta - - - 38654 4486.01 23.73 22.03 -0.107242605493065 Down 0.228536520935147 S6k RPS6-p70-protein kinase, isoform B K04688|1|0.0|889|dme:Dmel_CG10539|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0030529//ribonucleoprotein complex GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0006909//phagocytosis;GO:0048812//neuron projection morphogenesis;GO:0010259//multicellular organismal aging;GO:0030036//actin cytoskeleton organization;GO:0045927//positive regulation of growth;GO:0023060;GO:0030537//larval behavior;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0044248//cellular catabolic process;GO:0031667//response to nutrient levels 37655 2097.00 0.43 0.425 -0.0168738185643964 Down 0.0413749834896315 twi twist, isoform C K09069|1|0.0|671|dme:Dmel_CG2956|twist GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0042802//identical protein binding;GO:0016564//transcription repressor activity GO:0010004//gastrulation involving germ band extension;GO:0007267//cell-cell signaling;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0048333//mesodermal cell differentiation;GO:0001708//cell fate specification;GO:0055002//striated muscle cell development;GO:0009798//axis specification;GO:0001709//cell fate determination;GO:0007431//salivary gland development;GO:0010004//gastrulation involving germ band extension;GO:0007267//cell-cell signaling;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0048333//mesodermal cell differentiation;GO:0001708//cell fate specification;GO:0055002//striated muscle cell development;GO:0009798//axis specification;GO:0001709//cell fate determination;GO:0007431//salivary gland development 34764 503.00 0.495 1.02 1.04306872189189 Up 0.253500198124422 CG42810 CG42810 - - - - 318959 1500.00 0.055 0.145 1.39854937649027 Up 0.104972922995641 CG31815 CG31815 - - - - 34289 686.90 49.69 44.565 -0.157044435993539 Down 0.336745476159028 CG13117 CG13117, isoform B - - - - 43643 1283.32 0.67 1.655 1.30459821634944 Up 0.356656980583807 CG12069 CG12069, isoform C K04345|1|9e-85|313|dvi:Dvir_GJ22991|protein kinase A [EC:2.7.11.11] - GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 40064 3309.00 7.615 6.765 -0.170754102510755 Down 0.216616034869898 CG6841 CG6841 K12855|1|0.0|1744|dme:Dmel_CG6841|pre-mRNA-processing factor 6 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex - GO:0000380//alternative mRNA splicing, via spliceosome 5740218 824.00 0.23 0.01 -4.52356195605701 Down 0.229362039360719 326146 4082.00 8.37 14.215 0.764114571127184 Up 0.592061814819707 CG31510 CG31510 - GO:0044464//cell part GO:0046914//transition metal ion binding - 12797893 251.00 0.77 1.68 1.12553088208386 Up 0.336811517633074 CG43630 CG43630 - - - - 19835519 2211.00 0.02 0.01 -1 Down 0.0497292299564126 59173 2740.49 177.855 194.855 0.131699418539493 Up 0.31789063531898 CG18812 CG18812, isoform F K11251|1|5e-10|67.0|spu:576250|histone H2A - - - 5740489 795.00 0.315 0.82 1.38027208111817 Up 0.260170387003038 CG34430 CG34430 K06890|1|8e-16|84.0|ame:408303| - - - 39821 4079.44 5.46 5.195 -0.0717772020156406 Down 0.0983027341170255 RAF2 RING-associated factor 2, isoform C - - GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding - 41215 4539.00 9.44 10.605 0.167885856168714 Up 0.247193237353058 Teh1 tipE homolog 1, isoform B - - - GO:0010765//positive regulation of sodium ion transport 37069 4201.83 7.595 7.44 -0.0297473433940521 Down 0.071060626073174 Pcl polycomblike, isoform B K11485|1|0.0|1580|dme:Dmel_CG5109|polycomb-like protein 2 - - - 19836083 1197.00 0.01 0.15 3.90689059560852 Up 0.171410645885616 36059 2364.97 935.18 965.745 0.0463982267868906 Up 0.162429005415401 14-3-3zeta 14-3-3zeta, isoform L K06630|1|5e-134|479|dya:Dyak_GE19338|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0031647//regulation of protein stability;GO:0001745//compound eye morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0006587//serotonin biosynthetic process from tryptophan;GO:0044267//cellular protein metabolic process;GO:0008306//associative learning;GO:0007264//small GTPase mediated signal transduction 36916 1734.64 11.8 9.315 -0.341159185307566 Down 0.406947563069608 CG9640 CG9640, isoform B K11848|1|9e-09|62.0|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15] - - - 10178949 344.00 0.13 0.145 0.15754127698648 Up 0.0504556861709153 CG42681 CG42681 - - - - 19835476 1873.00 0.025 0.69 4.78659636189081 Up 0.385186897371549 - pre-mod(mdg4)-C - - - - 32582 2218.46 66.045 56.92 -0.214513683131567 Down 0.413650772685246 Mfe2 peroxisomal multifunctional enzyme type 2, isoform B K12405|1|0.0|1108|dme:Dmel_CG3415|3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase [EC:1.1.1.35 4.2.1.107] GO:0005777//peroxisome GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005488//binding GO:0006635//fatty acid beta-oxidation 39241 6160.72 9.79 10.445 0.0934317274634134 Up 0.156386210540219 JIL-1 JIL-1, isoform C K04445|1|5e-153|543|cfa:490831|mitogen-,stress activated protein kinases [EC:2.7.11.1] GO:0000785//chromatin;GO:0000805//X chromosome;GO:0000785//chromatin;GO:0000805//X chromosome GO:0032559;GO:0035174//histone serine kinase activity;GO:0032559;GO:0035174//histone serine kinase activity GO:0007143//female meiosis;GO:0051276//chromosome organization;GO:0006342//chromatin silencing;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation;GO:0007143//female meiosis;GO:0051276//chromosome organization;GO:0006342//chromatin silencing;GO:0006468//protein phosphorylation;GO:0007292//female gamete generation 44001 1518.00 17.385 18.11 0.0589434792225402 Up 0.138984282129177 Sucb sucb, isoform C K01900|1|0.0|808|dme:Dmel_CG10622|succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] GO:0044444//cytoplasmic part GO:0004774//succinate-CoA ligase activity;GO:0032559 GO:0009060//aerobic respiration 5740685 544.41 37.855 16.805 -1.17159332556496 Down 0.713082816008453 CG34165 CG34165, isoform B - - - - 10178802 2039.00 0.065 0.155 1.25375659224578 Up 0.103949280147933 43607 2906.45 26.07 39.745 0.608382795034966 Up 0.630431911240259 CG2217 CG2217, isoform D - - - - 40626 3233.00 9.515 8.67 -0.134171663052187 Down 0.198388588033285 Mms19 Mms19 - - - - 41208 2069.00 2.075 3.19 0.620445087530582 Up 0.332089552238806 CG8526 CG8526, isoform B K13278|1|0.0|1201|dsi:Dsim_GD18651|60kDa lysophospholipase [EC:3.1.1.5 3.1.1.47 3.5.1.1] - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0006519 31650 2529.00 11.66 17.24 0.564191985888602 Up 0.557522123893805 CG12541 CG12541, isoform E - - - - 3885572 1171.00 1.195 0.845 -0.499987371698564 Down 0.17864218729362 37909 908.00 0.175 0.48 1.45567948377619 Up 0.199015982036719 Ssl suppressor of Stellate-like K03115|1|3e-132|470|dme:Dmel_CG13591|casein kinase 2, beta polypeptide GO:0043234//protein complex GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process 19835518 501.00 3.87 0.475 -3.02633414781346 Down 0.629111081759345 19835243 1202.00 0.33 0.77 1.22239242133645 Up 0.236890767401928 36446 586.00 0.765 0.25 -1.61353165291793 Down 0.272520142649584 CG15870 CG15870 - - - - 42024 1660.00 0.31 0.36 0.215728691055437 Up 0.0663386606789064 CG14905 CG14905 K10421|1|1e-09|64.3|ssc:100153677|CAP-Gly domain-containing linker protein 1;K10383|2|2e-09|63.9|dre:373136|envoplakin;K10352|3|1e-08|61.6|dgr:Dgri_GH22039|myosin heavy chain - - - 32493 1653.00 12.105 12.07 -0.00417740324391512 Down 0.0434552899220711 CG7872 CG7872 K09523|1|2e-11|70.9|cel:C55B6.2|DnaJ homolog subfamily C member 3;K09531|3|2e-10|67.8|tgu:100219755|DnaJ homolog subfamily C member 11 - GO:0005515//protein binding - 42136 4514.00 3.74 4.52 0.273284502527551 Up 0.235470875709946 TyrR tyramine receptor, isoform C K04135|1|1e-61|238|api:100163236|adrenergic receptor alpha-1A;K04163|3|6e-40|166|bfo:BRAFLDRAFT_214670|5-hydroxytryptamine (serotonin) receptor 7;K04136|5|5e-37|156|tgu:100218481|adrenergic receptor alpha-1B - - - 39747 3910.00 16.515 17.995 0.123819132639202 Up 0.22995641262713 Hip14 Huntingtin-interacting protein 14, isoform C K11420|1|4e-16|87.4|mcc:721470|euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] GO:0030136//clathrin-coated vesicle GO:0046914//transition metal ion binding;GO:0016740//transferase activity GO:0023060;GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0065007//biological regulation 19835984 875.00 84.83 46.995 -0.85206729149539 Down 0.700567956676793 12797860 370.00 1.385 0.915 -0.598042327765145 Down 0.214733852859596 CG43209 CG43209 - - - - 43513 3158.00 5.63 6.385 0.181551697622494 Up 0.208625016510369 CG7837 CG7837 - GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0005488//binding;GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process 19836231 401.00 0.01 0.125 3.64385618977472 Up 0.151697265882974 - CG44625 - - - - 3771965 923.03 8.59 5.645 -0.605684550365463 Down 0.485801083080174 CG9515 CG9515, isoform B K01755|1|0.0|930|dme:Dmel_CG9510|argininosuccinate lyase [EC:4.3.2.1] GO:0044424//intracellular part GO:0016842 GO:0006526//arginine biosynthetic process 38866 4388.00 0.8 0.485 -0.722015252700235 Down 0.18095363888522 CG8492 CG8492 K01185|1|0.0|1815|dme:Dmel_CG8492|lysozyme [EC:3.2.1.17] - - - 34559 1339.29 4.205 4.19 -0.0051555565557925 Down 0.041044776119403 CG4788 CG4788, isoform B - - - - 12797910 539.00 0.305 0.105 -1.53841991478413 Down 0.158994848765024 CG43248 CG43248, isoform D - - - - 31240 4250.73 0.83 1.345 0.696422931209699 Up 0.229890371153084 Klp3A Kinesin-like protein at 3A, isoform B K10395|1|0.0|2115|dme:Dmel_CG8590|kinesin family member 4/7/21/27 - - - 34271 705.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG13113 CG13113 - - - - 38238 1018.05 127.105 96.54 -0.396822051660326 Down 0.59001452912429 GV1 GV1, isoform B - GO:0005635//nuclear envelope;GO:0005635//nuclear envelope - - 36634 4017.39 90.81 120.085 0.403132872066589 Up 0.589288072909787 CG12858 CG12858, isoform B K04604|1|5e-20|100|tca:657397|glutamate receptor, metabotropic 5 - - GO:0006810//transport 318624 1686.00 0.18 0.18 0 - 0.0382380134724607 CG31202 CG31202 K01230|1|0.0|1088|dme:Dmel_CG31202|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0015924 GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus 3355010 3382.00 29.46 33.09 0.16763786127669 Up 0.333773609826971 IntS3 integrator 3 K13140|1|0.0|2003|dse:Dsec_GM26749|integrator complex subunit 3 - - - 3771749 955.01 0.765 0.59 -0.374744793330811 Down 0.121021001188747 CG14929 CG14929, isoform B K10392|1|2e-07|58.5|mcc:695167|kinesin family member 1/13/14;K10396|3|6e-07|56.6|dre:565563|kinesin family member 5 - GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 34224 971.00 0.29 0.46 0.665580960929441 Up 0.126568485008585 CG17906 CG17906 - - - - 50350 1165.00 12.23 13.09 0.0980406934178539 Up 0.178939373926826 CG12994 CG12994 - - - - 32410 668.00 72.715 78.59 0.112092750901251 Up 0.268095363888522 CG14407 CG14407 K07390|1|2e-70|264|dme:Dmel_CG14407|monothiol glutaredoxin - GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis 40549 1567.00 0.2 0.33 0.722466024471091 Up 0.11306300356624 hkb huckebein K12379|1|8e-153|540|dme:Dmel_CG9768|huckebein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007276//gamete generation;GO:0007417//central nervous system development;GO:0009888//tissue development;GO:0001709//cell fate determination;GO:0007267//cell-cell signaling;GO:0009880//embryonic pattern specification;GO:0010004//gastrulation involving germ band extension;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009798//axis specification;GO:0007431//salivary gland development;GO:0006350;GO:0001704//formation of primary germ layer 35126 2500.00 12.79 11.41 -0.164717472592955 Down 0.256472064456479 CG10376 CG10376 K01090|1|2e-44|181|ssc:100152687|protein phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity - 36713 2547.38 25.245 20.27 -0.316651588584206 Down 0.470149253731343 CG8180 CG8180, isoform C - - - - 42913 1506.00 0.03 0.065 1.11547721741994 Up 0.0725795799762251 CG17781 CG17781 - - - - 33555 1393.00 15.235 15.145 -0.00854792189111311 Down 0.053625676925109 Ptpa phosphotyrosyl phosphatase activator - - GO:0019211//phosphatase activator activity GO:0019222//regulation of metabolic process 32375 1399.00 20.01 24.225 0.275775498396702 Up 0.431052701096288 mRpL38 mitochondrial ribosomal protein L38 - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 246506 808.00 0.3 0.39 0.37851162325373 Up 0.0904437987055871 CG30184 CG30184 - - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0004091//carboxylesterase activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 38844 4815.42 25.145 28.415 0.176381161972545 Up 0.336811517633074 CG7546 CG7546, isoform H - - - - 31826 5962.32 86.775 141.005 0.700394955949063 Up 0.685972790912693 rdgA retinal degeneration A, isoform K K00901|1|0.0|1672|dme:Dmel_CG34344|diacylglycerol kinase [EC:2.7.1.107] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0008289//lipid binding;GO:0016301//kinase activity GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030384;GO:0009266//response to temperature stimulus;GO:0046394;GO:0030036//actin cytoskeleton organization;GO:0016310//phosphorylation;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030384;GO:0009266//response to temperature stimulus;GO:0046394;GO:0030036//actin cytoskeleton organization;GO:0016310//phosphorylation;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030384;GO:0009266//response to temperature stimulus;GO:0046394;GO:0030036//actin cytoskeleton organization;GO:0016310//phosphorylation;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030384;GO:0009266//response to temperature stimulus;GO:0046394;GO:0030036//actin cytoskeleton organization;GO:0016310//phosphorylation;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030384;GO:0009266//response to temperature stimulus;GO:0046394;GO:0030036//actin cytoskeleton organization;GO:0016310//phosphorylation;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030384;GO:0009266//response to temperature stimulus;GO:0046394;GO:0030036//actin cytoskeleton organization;GO:0016310//phosphorylation;GO:0043954//cellular component maintenance 2768666 1681.00 16.71 11.305 -0.563750741309659 Down 0.554418174613657 Sp212 Serine-peptidase 212 K01362|1|4e-27|122|dpo:Dpse_GA13461| [EC:3.4.21.-];K01344|3|2e-19|97.8|xtr:548476|protein C (activated) [EC:3.4.21.69];K09626|4|1e-18|94.7|rno:302971|protease, serine, 22 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 317969 736.10 1.255 1.855 0.563731822670031 Up 0.240985338792762 CG42355 CG42355, isoform D - - - - 31641 2240.00 2.26 3.775 0.740153871797254 Up 0.396446968696341 CG4586 CG4586 K00232|1|0.0|1269|dme:Dmel_CG4586|acyl-CoA oxidase [EC:1.3.3.6];K00249|1|0.0|1269|dme:Dmel_CG4586|acyl-CoA dehydrogenase [EC:1.3.99.3] - - - 41043 3092.00 6.155 6.46 0.0697753082094676 Up 0.104906881521596 CG8202 CG8202 - - - - 33572 978.00 2.685 0.585 -2.19841355840201 Down 0.521628582749967 CG31954 CG31954 K01312|1|7e-65|247|dme:Dmel_CG9564|trypsin [EC:3.4.21.4];K01324|3|3e-43|175|mdo:100013981|plasma kallikrein [EC:3.4.21.34];K09636|4|3e-43|175|rno:266681|transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462822 670.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 40583 5169.14 61.35 69.985 0.189982396104257 Up 0.39040417382116 CG43427 CG43427, isoform P K06084|1|2e-65|251|nvi:100123436|F-box protein 20 - GO:0046914//transition metal ion binding - 8674048 221.00 2.535 1.24 -1.03164562661647 Down 0.391460837405891 Sfp36F seminal fluid protein 36F, isoform B - - - - 38325 725.03 51.43 36.515 -0.494120923117759 Down 0.605270109628847 CG16986 CG16986, isoform B - - - - 34160 2448.64 40.56 43.89 0.113834617856302 Up 0.255844670453044 CG13384 CG13384, isoform L - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity - 40649 1287.00 2.29 0.76 -1.59127627465336 Down 0.446869634130234 CG2663 CG2663, isoform C K10693|1|2e-28|126|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K00683|2|1e-08|60.8|tca:659407|glutaminyl-peptide cyclotransferase [EC:2.3.2.5];K01104|3|9e-08|58.2|hmg:100203076|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part;GO:0044464//cell part - GO:0051234//establishment of localization;GO:0051234//establishment of localization 35253 1558.05 60.805 69.185 0.186269319575223 Up 0.389545634658566 spi spitz, isoform G K02447|1|1e-06|55.1|dpo:Dpse_GA25451|protein gruken precursor;K04357|2|2e-06|53.9|tgu:100218747|epidermal growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0005154//epidermal growth factor receptor binding;GO:0005154//epidermal growth factor receptor binding;GO:0005154//epidermal growth factor receptor binding;GO:0005154//epidermal growth factor receptor binding;GO:0005154//epidermal growth factor receptor binding GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0001742//oenocyte differentiation;GO:0030534//adult behavior;GO:0035468;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007445;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0001742//oenocyte differentiation;GO:0030534//adult behavior;GO:0035468;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007445;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0001742//oenocyte differentiation;GO:0030534//adult behavior;GO:0035468;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007445;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0001742//oenocyte differentiation;GO:0030534//adult behavior;GO:0035468;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007445;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0001742//oenocyte differentiation;GO:0030534//adult behavior;GO:0035468;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0022402//cell cycle process;GO:0001709//cell fate determination;GO:0007445;GO:0007399//nervous system development;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process 34554 1284.00 338.905 218.915 -0.630510110629387 Down 0.68118478404438 CG6287 CG6287 K00058|1|1e-177|622|dme:Dmel_CG6287|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding GO:0006563//L-serine metabolic process 38220 2151.15 0.105 0.18 0.777607578663552 Up 0.0872738079513935 CG18173 CG18173, isoform B K05283|1|3e-112|405|dmo:Dmoj_GI12778|phosphatidylinositol glycan, class W [EC:2.3.-.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016740//transferase activity GO:0006497//protein lipidation 5740554 1052.00 0.04 0.01 -2 Down 0.0694426099590543 CG34448 CG34448 K01046|1|2e-31|136|rno:84028|triacylglycerol lipase [EC:3.1.1.3] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 3772149 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33803 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 36302 3977.97 15.105 16.99 0.16965966845628 Up 0.28939373926826 CG8878 CG8878, isoform C K08816|1|3e-34|148|phu:Phum_PHUM466010|vaccinia related kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 31609 4547.81 16.6 18.74 0.1749377114249 Up 0.299266939638093 CG14442 CG14442, isoform E - - - - 14462847 953.00 1.73 1.195 -0.533761419655976 Down 0.226126007132479 35480 3040.32 36.01 34.15 -0.0765120210128276 Down 0.193666622639017 Atf6 Atf6, isoform C K09054|1|0.0|1381|dme:Dmel_CG3136|activating transcription factor 6 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 47253 2426.00 5.36 3.445 -0.637729017753481 Down 0.42296262052569 dmGlut dietary and metabolic glutamate transporter K08193|1|0.0|847|dpo:Dpse_GA18795|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0006810//transport;GO:0023060 37538 1713.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG3292 CG3292 K01077|1|0.0|1072|dme:Dmel_CG3292|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 38571 1188.00 0.65 1.22 0.908369524534432 Up 0.258354246466781 CG7514 CG7514 K13577|1|2e-44|179|nvi:100121559|mitochondrial dicarboxylate carrier GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0015140//malate transmembrane transporter activity GO:0046907//intracellular transport;GO:0015740//C4-dicarboxylate transport 41110 857.00 0.095 0.065 -0.547487795302493 Down 0.0619138819178444 CG12951 CG12951 K01312|1|4e-28|124|dme:Dmel_CG12386|trypsin [EC:3.4.21.4];K01324|4|5e-26|117|bta:533547|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43010 2116.23 0.325 0.13 -1.32192809488736 Down 0.152852991678774 fd96Ca forkhead domain 96Ca, isoform B K09411|1|0.0|672|dme:Dmel_CG11921|forkhead box protein, other GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048731;GO:0045449;GO:0006351//transcription, DNA-dependent 318571 455.06 0.33 1.74 2.39854937649027 Up 0.45598335754854 CG31050 CG31050, isoform B - - - - 35555 7065.58 6.785 8.015 0.240353704735694 Up 0.280643243957205 jing jing, isoform J K06230|1|4e-09|65.1|gga:396045|zinc finger protein GLI GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0005488//binding GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0007297//ovarian follicle cell migration;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0007380//specification of segmental identity, head;GO:0007399//nervous system development;GO:0060541//respiratory system development;GO:0009888//tissue development;GO:0010467//gene expression;GO:0007297//ovarian follicle cell migration;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0007380//specification of segmental identity, head;GO:0007399//nervous system development;GO:0060541//respiratory system development;GO:0009888//tissue development;GO:0010467//gene expression;GO:0007297//ovarian follicle cell migration;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006935//chemotaxis;GO:0007380//specification of segmental identity, head;GO:0007399//nervous system development;GO:0060541//respiratory system development 318622 3019.00 1.9 3.935 1.05036421717654 Up 0.469786025624092 CG31198 CG31198 K11140|1|2e-138|493|ame:412808|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 35745 1877.67 2.58 2.04 -0.338801913451759 Down 0.209582617884031 CG8791 CG8791, isoform C K08193|1|3e-89|329|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|5|8e-73|275|rno:363103|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - GO:0006810//transport 42036 1711.00 0.29 0.57 0.97490901903717 Up 0.178278959186369 Glut3 glucose transporter type 3 K08145|1|8e-29|128|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 - - - 37062 897.00 2.88 3.73 0.373106818812926 Up 0.267302866199974 CG5757 CG5757, isoform B K00943|1|2e-117|421|dme:Dmel_CG5757|dTMP kinase [EC:2.7.4.9] - - - 40619 2674.54 8.185 10.19 0.316099729691661 Up 0.372870162462026 dpr16 dpr16, isoform C - - - - 33682 1208.16 19.27 20.39 0.0815052037208753 Up 0.175439175802404 CG2976 CG2976, isoform B K05955|1|0.0|676|dme:Dmel_CG2976|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59] - GO:0008318//protein prenyltransferase activity - 33144 1934.00 40.695 18.35 -1.14907148527245 Down 0.714007396645093 Cda4 chitin deacetylase-like 4 K01183|1|2e-06|54.7|dwi:Dwil_GK23269|chitinase [EC:3.2.1.14] - GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity GO:0006022 37071 701.00 61.535 63.26 0.0398863329875608 Up 0.130134724607053 CG17680 CG17680 - - - - 42898 7244.00 9.925 10.215 0.0415501967029071 Up 0.0919627526086382 BRWD3 BRWD3 K11798|1|0.0|3238|dme:Dmel_CG31132|bromodomain and WD repeat domain containing protein 1/3;K11797|2|0.0|2294|dpo:Dpse_GA16032|PH-interacting protein - - - 38383 932.00 1.42 1.22 -0.219009781941796 Down 0.111841236296394 CG14963 CG14963 - - - - 32276 913.05 0.545 0.91 0.73961031542177 Up 0.195251618016114 CG15742 CG15742, isoform C - - - - 33332 1526.36 9.175 8.95 -0.0358204755789566 Down 0.084070796460177 CG7420 CG7420, isoform B K00502|1|6e-34|145|mcc:695363|tryptophan 5-monooxygenase [EC:1.14.16.4] - - - 32046 12204.00 5.87 7.115 0.27750325341643 Up 0.297186633205653 CG11122 CG11122 K13431|1|0.0|1039|dse:Dsec_GM11265|signal recognition particle receptor subunit alpha - GO:0005488//binding - 41892 1019.00 0.27 0.34 0.332575339086871 Up 0.0806036190727777 CG5213 CG5213 K13208|1|2e-33|143|dre:30065|ELAV like protein 2/3/4 - - - 42005 1390.00 23.525 23.045 -0.0297409552792501 Down 0.0960903447364945 Der-2 Derlin-2 K13989|1|6e-156|510|dsi:Dsim_GD20283|Derlin-2/3 - - - 36359 918.00 1.77 0.83 -1.09256611873607 Down 0.339486197331924 CG13154 CG13154 - - - - 19835364 510.00 0.76 0.92 0.275634442613427 Up 0.107416457535332 32271 2113.00 0.025 0.03 0.263034405833794 Up 0.0467903843613789 CG12723 CG12723 - - - - 33721 1733.37 417.67 437.43 0.066688644563021 Up 0.20353982300885 Rtnl1 Reticulon-like1, isoform L - GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005783//endoplasmic reticulum - GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior 12797894 488.00 0.51 0.1 -2.35049724708413 Down 0.25475498613129 CG43063 CG43063 - - - - 31465 1307.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 CG4151 CG4151, isoform B - - - - 33029 1178.00 0.36 0.475 0.399930606888635 Up 0.101868973715493 CG1631 CG1631 - - - - 19834800 916.00 0.05 0.15 1.58496250072116 Up 0.1121384229296 3346226 1514.00 0.085 0.13 0.612976876890753 Up 0.0687491744815744 ppk13 pickpocket 13 K04828|1|1e-07|58.2|bta:617930|amiloride-sensitive cation channel 1, neuronal (degenerin) GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 34604 1886.38 195.99 198.04 0.0150118088398597 Up 0.0911702549200898 Cry crystallin, isoform B - GO:0005635//nuclear envelope GO:0030528//transcription regulator activity;GO:0004930//G-protein coupled receptor activity;GO:0030554//adenyl nucleotide binding;GO:0016830//carbon-carbon lyase activity;GO:0042302//structural constituent of cuticle;GO:0009881//photoreceptor activity GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007602//phototransduction;GO:0006355//regulation of transcription, DNA-dependent;GO:0009629//response to gravity;GO:0009648//photoperiodism;GO:0050962//detection of light stimulus involved in sensory perception;GO:0006606//protein import into nucleus 43930 5535.00 4.035 2.405 -0.746531779507738 Down 0.408433496235636 prc pericardin K02184|1|2e-16|89.4|hsa:56776|formin 2 - - - 19835172 426.00 0.59 0.225 -1.39078995303217 Down 0.218630299828292 38519 1859.00 43.895 51.615 0.233733778457417 Up 0.426462818650112 CG1309 CG1309 - - - - 19835382 480.00 0.44 0.615 0.483082886701943 Up 0.125181614053626 44121 579.00 151.945 120.56 -0.333797879341028 Down 0.551380266807555 TotA turandot A - GO:0044421//extracellular region part - GO:0051707//response to other organism;GO:0009416//response to light stimulus;GO:0006952//defense response;GO:0009605//response to external stimulus 31732 2004.00 4.65 4.095 -0.183367264354385 Down 0.179236560560032 CG2260 CG2260 K03130|1|4e-06|53.5|hmg:100208823|transcription initiation factor TFIID subunit D4 - - - 31224 8585.98 22.905 44.665 0.963482199084471 Up 0.696935675604279 PsGEF Protostome-specific GEF, isoform I K05629|1|5e-06|54.7|dre:564112|atrophin-1 interacting protein 1 GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding GO:0007266//Rho protein signal transduction;GO:0007420//brain development;GO:0007420//brain development 12798039 671.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 40019 3735.00 6.885 7.585 0.139692526112069 Up 0.188086118082156 AlCR2 allatostatin C receptor 1, isoform E K04218|1|7e-61|235|bta:282083|somatostatin receptor 2;K04221|2|9e-61|235|mdo:100021753|somatostatin receptor 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 31517 2388.00 16.28 16.675 0.0345860618057003 Up 0.0922599392418439 CG3033 glycosylphosphatidylinositol anchor attachment 1 ortholog K05289|1|0.0|1226|dme:Dmel_CG3033|glycosylphosphatidylinositol transamidase - - - 36034 562.00 9.62 4.745 -1.01962880674893 Down 0.597113987584203 CG15863 CG15863 K00504|1|4e-10|64.7|ame:408568|peptidylglycine monooxygenase [EC:1.14.17.3] GO:0043234//protein complex;GO:0044297//cell body GO:0046914//transition metal ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016842;GO:0005515//protein binding GO:0044267//cellular protein metabolic process 19834898 680.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 33528 471.55 302.235 274.65 -0.138076448072536 Down 0.337570994584599 CG12400 CG12400, isoform B K03968|1|2e-51|200|dme:Dmel_CG12400|NADH dehydrogenase (ubiquinone) 1 subcomplex unknown 2 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain 43264 1130.00 12.24 12.54 0.034933790109387 Up 0.0864152687887994 CG6074 CG6074 K01672|1|0.0|646|dme:Dmel_CG6074|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 326108 379.48 100.96 88.79 -0.185314708551367 Down 0.398989565447101 PebII protein ejaculatory bulb II, isoform B - - - - 40512 3559.00 0.065 0.04 -0.700439718141092 Down 0.0550785893541144 BoYb brother of Yb K12823|1|6e-08|60.5|bmy:Bm1_52675|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled - 34589 808.00 0.21 0.5 1.25153876699596 Up 0.189737154933298 CG14932 CG14932, isoform C - - - - 33986 4090.72 82.835 42.42 -0.965495852862504 Down 0.714370624752344 ade3 adenosine 3, isoform C K11787|1|0.0|2487|dsi:Dsim_GD22518|phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0043169//cation binding;GO:0016882//cyclo-ligase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0032559;GO:0043169//cation binding;GO:0016882//cyclo-ligase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0032559 GO:0006144//purine nucleobase metabolic process;GO:0006188//IMP biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0006188//IMP biosynthetic process 40818 622.00 0.135 0.18 0.415037499278844 Up 0.0678576145819575 Edg84A Ecdysone-dependent gene 84A - - GO:0005214//structural constituent of chitin-based cuticle - 12798422 618.00 0.01 0.22 4.4594316186373 Up 0.222989037115308 CG43318 CG43318 - - - - 31966 1255.00 0.44 0.535 0.28203536776385 Up 0.0849623563597939 CG2898 CG2898 - - - - 12797932 1679.00 2.405 1.34 -0.843803893312269 Down 0.344604411570466 42577 3066.00 0.135 0.255 0.917537839808027 Up 0.113492273147537 CG31465 CG31465, isoform C - - - - 34236 1134.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 Or30a odorant receptor 30a K08471|1|0.0|755|dme:Dmel_CG13106|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 41390 2058.70 37.945 41.695 0.135964593561413 Up 0.301743494914807 wkd whacked, isoform B K11837|1|2e-23|111|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K13136|2|7e-06|52.8|nvi:100114269|gem associated protein 8 GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0060446//branching involved in open tracheal system development;GO:0032318//regulation of Ras GTPase activity;GO:0060446//branching involved in open tracheal system development;GO:0032318//regulation of Ras GTPase activity 35181 4073.08 15.86 15.6 -0.0238467419543678 Down 0.0738343679830934 CG10702 CG10702, isoform D K04527|1|8e-80|299|dre:245699|insulin receptor [EC:2.7.10.1];K05087|2|5e-75|283|gga:395889|insulin-like growth factor 1 receptor [EC:2.7.10.1] GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0007275//multicellular organismal development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0050789//regulation of biological process;GO:0006464//cellular protein modification process;GO:0007275//multicellular organismal development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0050789//regulation of biological process;GO:0006464//cellular protein modification process;GO:0007275//multicellular organismal development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0050789//regulation of biological process;GO:0006464//cellular protein modification process;GO:0007275//multicellular organismal development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0050789//regulation of biological process;GO:0006464//cellular protein modification process 40775 1270.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 Osi18 osiris 18 - - - - 37087 677.00 0.65 0.79 0.281412935148649 Up 0.100878351604808 CG14500 CG14500 K06560|1|3e-06|51.6|mdo:100025542|mannose receptor, C type - - - 14462559 300.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 19836226 600.00 0.805 0.38 -1.08298936467103 Down 0.229857350416061 5740334 632.99 0.635 0.145 -2.13070369164459 Down 0.274039096552635 CG34300 CG34300, isoform B - - - - 36045 3789.98 38.215 38.015 -0.00757023928194956 Down 0.0608572183331132 oys oysgedart, isoform E K13517|1|2e-145|517|tca:662787|lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] GO:0031224//intrinsic to membrane GO:0030247//polysaccharide binding GO:0006022 31413 1985.00 0.06 0.055 -0.125530882083859 Down 0.0382380134724607 CG6978 CG6978 K08193|1|0.0|970|dme:Dmel_CG6978|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|4|1e-91|337|xtr:780284|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 GO:0031224//intrinsic to membrane GO:0005436//sodium:phosphate symporter activity GO:0015698//inorganic anion transport 41850 1496.00 11.885 11.8 -0.0103550436932312 Down 0.053625676925109 MRG15 MRG15, isoform B K11339|1|8e-179|626|dme:Dmel_CG6363|mortality factor 4-like protein 1 - - - 32996 629.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 skpC skpC K03094|1|7e-87|318|dme:Dmel_CG11941|S-phase kinase-associated protein 1 GO:0005815//microtubule organizing center;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding GO:0051276//chromosome organization;GO:0019941//modification-dependent protein catabolic process;GO:0006261//DNA-dependent DNA replication;GO:0046605//regulation of centrosome cycle 19835095 1639.00 4.435 3.06 -0.535402451608412 Down 0.358968432175406 34772 5967.51 10.4 10.565 0.0227092389064865 Up 0.0666688680491349 kuz kuzbanian, isoform G K06704|1|0.0|1918|dya:Dyak_GE18670|disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81] - GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis;GO:0007297//ovarian follicle cell migration;GO:0001558//regulation of cell growth;GO:0009887//organ morphogenesis;GO:0048534;GO:0007399//nervous system development;GO:0014706//striated muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0035051//cardiocyte differentiation;GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis;GO:0007297//ovarian follicle cell migration;GO:0001558//regulation of cell growth;GO:0009887//organ morphogenesis;GO:0048534;GO:0007399//nervous system development;GO:0014706//striated muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0035051//cardiocyte differentiation;GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis;GO:0007297//ovarian follicle cell migration;GO:0001558//regulation of cell growth;GO:0009887//organ morphogenesis;GO:0048534;GO:0007399//nervous system development;GO:0014706//striated muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0035051//cardiocyte differentiation;GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis;GO:0007297//ovarian follicle cell migration;GO:0001558//regulation of cell growth;GO:0009887//organ morphogenesis;GO:0048534;GO:0007399//nervous system development;GO:0014706//striated muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0035051//cardiocyte differentiation;GO:0044267//cellular protein metabolic process;GO:0006909//phagocytosis;GO:0007297//ovarian follicle cell migration;GO:0001558//regulation of cell growth;GO:0009887//organ morphogenesis;GO:0048534;GO:0007399//nervous system development;GO:0014706//striated muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0035051//cardiocyte differentiation 318747 554.00 6.435 5.51 -0.223887829649544 Down 0.240820235107648 CG31460 CG31460, isoform B - GO:0044421//extracellular region part;GO:0031224//intrinsic to membrane - - 19835689 401.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 43327 1542.00 11.19 13.955 0.318572088089673 Up 0.412627129837538 Sce Sex combs extra K10695|1|6e-178|624|dme:Dmel_CG5595|E3 ubiquitin-protein ligase RNF1/2 [EC:6.3.2.19] GO:0031519//PcG protein complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0007293//germarium-derived egg chamber formation;GO:0016458//gene silencing;GO:0007423//sensory organ development;GO:0007059//chromosome segregation;GO:0007399//nervous system development;GO:0000904//cell morphogenesis involved in differentiation 19834916 1101.00 0.225 0.12 -0.906890595608518 Down 0.103619072777704 3354934 1728.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 CG40188 CG40188 - - - - 41593 1136.00 0.66 0.75 0.184424571137428 Up 0.0784902919033153 CG14383 CG14383 - - - - 32877 7281.71 8.63 10.195 0.240429310837642 Up 0.30745608241976 CG34422 CG34422, isoform D K11653|1|1e-07|60.5|isc:IscW_ISCW014189|AT-rich interactive domain-containing protein 1;K11765|2|2e-07|59.7|nvi:100121989|AT-rich interactive domain-containing protein 2 GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006909//phagocytosis;GO:0006325//chromatin organization 42030 1177.00 4.17 4.495 0.108273732069784 Up 0.123200369832255 CG14906 CG14906 - - - - 5740542 1108.00 0.28 0.465 0.731803889050427 Up 0.132809404305904 CG41561 CG41561 - - - - 318059 5291.57 10.415 12.765 0.293530698366472 Up 0.379540351340642 CG32506 CG32506, isoform D K13136|1|2e-27|125|nvi:100114269|gem associated protein 8 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 53438 5041.00 0.665 0.435 -0.612338939652461 Down 0.145456346585656 RecQ4 RecQ4 K10730|1|0.0|2825|dme:Dmel_CG7487|ATP-dependent DNA helicase Q4 [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0046914//transition metal ion binding;GO:0032559;GO:0003690//double-stranded DNA binding;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity GO:0006277//DNA amplification;GO:0006275//regulation of DNA replication;GO:0008283//cell proliferation;GO:0009791//post-embryonic development;GO:0035561//regulation of chromatin binding;GO:0007292//female gamete generation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006281//DNA repair 42879 4088.00 3.12 1.455 -1.10052687595396 Down 0.436666226390173 CG17786 CG17786 - - - - 43329 1197.00 5.75 5.655 -0.0240349318419172 Down 0.0586448289525822 CG43320 CG43320 K00476|1|5e-07|56.2|mdo:100010508|aspartate beta-hydroxylase [EC:1.14.11.16] - - - 40002 1544.00 11.315 9.85 -0.200040954923154 Down 0.284011359133536 CG5147 CG5147 K03026|1|0.0|655|dme:Dmel_CG5147|DNA-directed RNA polymerase III subunit C4 [EC:2.7.7.6] GO:0044451//nucleoplasm part GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 35098 646.90 854.1 888.265 0.0565851525391685 Up 0.185180293224145 RpS26 ribosomal protein S26, isoform E K02976|1|3e-51|201|dya:Dyak_GE12733|small subunit ribosomal protein S26e GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression 39880 1594.75 25.16 18.97 -0.407412243467814 Down 0.525591071192709 CG13024 CG13024, isoform C - - - - 12798583 372.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 CG43232 CG43232 - - - - 3355173 1286.00 0.21 0.235 0.162271428898877 Up 0.0554418174613657 Pp1-Y2 Pp1-Y2 K01090|1|3e-172|603|dme:Dmel_CG40448|protein phosphatase [EC:3.1.3.16];K06269|2|1e-125|449|tca:100141788|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] - GO:0016791//phosphatase activity GO:0048646//anatomical structure formation involved in morphogenesis 38457 1105.00 56.135 55.21 -0.0239709661682055 Down 0.0877030775326905 Sc2 Sc2 K10258|1|3e-170|597|dme:Dmel_CG10849|enoyl reductase [EC:1.3.1.-] GO:0044424//intracellular part;GO:0031224//intrinsic to membrane GO:0016491//oxidoreductase activity GO:0044238//primary metabolic process 8674115 418.00 13.285 9.7 -0.453741575416017 Down 0.483489631488575 Sfp33A3 seminal fluid protein 33A3 - - - - 326260 2301.00 10.6 9.205 -0.203574638100655 Down 0.278331792365606 CG33120 CG33120 - - - - 3772099 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33908 histone H2B K11252|1|6e-48|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 35616 1188.00 25.755 23.695 -0.12026987909069 Down 0.249372605996566 Tsp42Eg tetraspanin 42Eg - GO:0031224//intrinsic to membrane - - 39976 2587.02 22.55 17.375 -0.376114455644511 Down 0.500660414740457 Adgf-A adenosine deaminase-related growth factor A, isoform B K01488|1|0.0|1128|dme:Dmel_CG5992|adenosine deaminase [EC:3.5.4.4] GO:0044421//extracellular region part;GO:0044421//extracellular region part GO:0005102//receptor binding;GO:0003824//catalytic activity;GO:0005102//receptor binding;GO:0003824//catalytic activity GO:0002376//immune system process;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0002376//immune system process;GO:0009127//purine nucleoside monophosphate biosynthetic process 5740763 137.00 0.01 0.485 5.59991284218713 Up 0.355831462158235 317815 5089.21 135.985 155.145 0.190169680638145 Up 0.406749438647471 CG32000 CG32000, isoform I K01552|1|0.0|714|cel:W08D2.5| [EC:3.6.3.-];K13526|2|8e-144|512|mdo:100026165|ATPase type 13A2 - - - 36189 817.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 Cpr47Eb cuticular protein 47Eb - - GO:0042302//structural constituent of cuticle - 41308 1962.00 12.36 15.89 0.362440381444145 Up 0.454827631752741 CG6574 CG6574 - GO:0044464//cell part GO:0015291//secondary active transmembrane transporter activity;GO:0016597//amino acid binding GO:0051234//establishment of localization 40074 2522.00 4.205 4.3 0.0322308593343162 Up 0.0618808611808216 CG3808 CG3808 - - GO:0005488//binding;GO:0008168//methyltransferase activity GO:0010467//gene expression 33487 428.55 613.965 579.43 -0.0835220328277134 Down 0.225366530180954 RpS21 ribosomal protein S21, isoform F K02971|1|4e-42|171|dya:Dyak_GE18186|small subunit ribosomal protein S21e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0043021//ribonucleoprotein complex binding;GO:0005198//structural molecule activity;GO:0043021//ribonucleoprotein complex binding;GO:0005198//structural molecule activity;GO:0043021//ribonucleoprotein complex binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0042254//ribosome biogenesis;GO:0008283//cell proliferation;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0042254//ribosome biogenesis;GO:0008283//cell proliferation;GO:0006412//translation;GO:0032501//multicellular organismal process;GO:0042254//ribosome biogenesis;GO:0008283//cell proliferation 31776 2108.23 57.035 41.64 -0.453877444151106 Down 0.593613789459781 CG1440 CG1440, isoform D K01372|1|0.0|929|dse:Dsec_GM21572|bleomycin hydrolase [EC:3.4.22.40] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 35222 1363.97 206.545 151.26 -0.449425612113848 Down 0.621681415929204 CG10237 CG10237, isoform E K01104|1|3e-11|70.1|phu:Phum_PHUM243230|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0019842//vitamin binding;GO:0019842//vitamin binding;GO:0019842//vitamin binding GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 317930 2928.00 0.115 0.245 1.0911478880582 Up 0.122176726984546 CG32232 CG32232 - GO:0015630//microtubule cytoskeleton;GO:0044430//cytoskeletal part - GO:0007010//cytoskeleton organization 12797902 701.00 0.985 0.595 -0.727234056148433 Down 0.202417117950073 CG43179 CG43179 - - - - 32343 5160.35 28.65 31.375 0.13108032008123 Up 0.277077004358737 inaE inactivation no afterpotential E, isoform H K13806|1|0.0|1305|dme:Dmel_CG33174|sn1-specific diacylglycerol lipase alpha [EC:3.1.1.-] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity;GO:0004091//carboxylesterase activity GO:0007165//signal transduction;GO:0044238//primary metabolic process;GO:0007165//signal transduction;GO:0044238//primary metabolic process;GO:0007165//signal transduction;GO:0044238//primary metabolic process;GO:0007165//signal transduction;GO:0044238//primary metabolic process 31874 2808.94 9.415 10.08 0.0984626388856884 Up 0.163650772685246 ric8a ric8a, isoform B - GO:0044444//cytoplasmic part GO:0030695//GTPase regulator activity;GO:0005515//protein binding GO:0000278//mitotic cell cycle;GO:0045165//cell fate commitment;GO:0031647//regulation of protein stability;GO:0048103//somatic stem cell division;GO:0001703//gastrulation with mouth forming first;GO:0008104//protein localization 38365 764.00 4.79 6.52 0.444846308494897 Up 0.378846915863162 CG16753 CG16753 - - - - 40527 4313.40 23.595 25.54 0.114277353565881 Up 0.235338792761854 aux auxillin, isoform D K08282|1|0.0|2236|dme:Dmel_CG1107|non-specific serine/threonine protein kinase [EC:2.7.11.1];K08855|3|1e-154|548|cin:100186907|cyclin G-associated kinase [EC:2.7.11.1] - GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032559;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032559 GO:0048592//eye morphogenesis;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0048592//eye morphogenesis;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway 37673 1262.00 0.85 1.385 0.704351229911486 Up 0.234579315810329 CG13544 CG13544 K10357|1|9e-06|51.6|nvi:100120420|myosin V - - - 31879 1300.00 0.14 0.24 0.777607578663552 Up 0.101505745608242 CG17440 CG17440 K11728|1|1e-11|70.9|dre:324479|nucleosome-remodeling factor subunit BPTF - GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 36681 1948.32 383.21 331.31 -0.209953459954321 Down 0.440496631884824 igl igloo, isoform C K08834|1|3e-07|57.0|dre:402814|myosin III [EC:2.7.11.1] - GO:0017022//myosin binding;GO:0017022//myosin binding - 37094 607.00 1.56 0.605 -1.36653898158765 Down 0.356095628054418 CG18537 CG18537 - - - - 35528 2514.38 1.46 0.91 -0.682029918681321 Down 0.23702285035002 dream dream, isoform B K04489|1|2e-19|98.2|cqu:CpipJ_CPIJ000671|caspase invertebrate, apoptosis-related cysteine protease [EC:3.4.22.-] GO:0044424//intracellular part GO:0004175//endopeptidase activity GO:0012502//induction of programmed cell death;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007435//salivary gland morphogenesis;GO:0019538//protein metabolic process 33202 2023.00 39.925 29.035 -0.459499373595906 Down 0.581429137498349 Hop Hsp70/Hsp90 organizing protein homolog K09553|1|0.0|885|dme:Dmel_CG2720|stress-induced-phosphoprotein 1 GO:0043232 GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0035168//larval lymph gland hemocyte differentiation;GO:0009880//embryonic pattern specification;GO:0017145//stem cell division;GO:0008360//regulation of cell shape;GO:0048859//formation of anatomical boundary;GO:0001745//compound eye morphogenesis;GO:0003382//epithelial cell morphogenesis;GO:0006955//immune response;GO:0042074//cell migration involved in gastrulation;GO:0007478//leg disc morphogenesis;GO:0007259//JAK-STAT cascade;GO:0007297//ovarian follicle cell migration;GO:0001736//establishment of planar polarity;GO:0003002//regionalization;GO:0002252;GO:0000060//protein import into nucleus, translocation;GO:0007281//germ cell development;GO:0006464//cellular protein modification process;GO:0002682//regulation of immune system process;GO:0060541//respiratory system development;GO:0006952//defense response;GO:0007472//wing disc morphogenesis 38109 5694.28 47.6 49.75 0.0637349521230678 Up 0.167910447761194 Glut1 glucose transporter 1, isoform Z K07299|1|2e-85|317|spu:590274|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1;K08142|2|9e-82|305|gga:396517|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3 GO:0031224//intrinsic to membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic to membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic to membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic to membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic to membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic to membrane;GO:0031981//nuclear lumen GO:0015149//hexose transmembrane transporter activity;GO:0032561//guanyl ribonucleotide binding;GO:0015149//hexose transmembrane transporter activity;GO:0032561//guanyl ribonucleotide binding;GO:0015149//hexose transmembrane transporter activity;GO:0032561//guanyl ribonucleotide binding;GO:0015149//hexose transmembrane transporter activity;GO:0032561//guanyl ribonucleotide binding;GO:0015149//hexose transmembrane transporter activity;GO:0032561//guanyl ribonucleotide binding;GO:0015149//hexose transmembrane transporter activity;GO:0032561//guanyl ribonucleotide binding GO:0008283//cell proliferation;GO:0006810//transport;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0006810//transport;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0006810//transport;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0006810//transport;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0006810//transport;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0006810//transport;GO:0007049//cell cycle 19835046 552.00 0.615 0.905 0.557331381743966 Up 0.163287544577995 35697 3062.22 81.595 70.965 -0.201373087486151 Down 0.407277770439836 CG1358 CG1358, isoform D K08220|1|7e-121|435|mcc:710008|MFS transporter, FLVCR family, feline leukemia virus subgroup C cellular receptor - - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 33648 1749.00 12.31 15.08 0.292805666784207 Up 0.39816404702153 morgue modifier of rpr and grim, ubiquitously expressed K06689|1|0.0|848|dme:Dmel_CG15437|ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] GO:0031461//cullin-RING ubiquitin ligase complex GO:0019787//small conjugating protein ligase activity GO:0012502//induction of programmed cell death;GO:0032446//protein modification by small protein conjugation;GO:0060255;GO:0046672//positive regulation of compound eye retinal cell programmed cell death 317842 440.00 0.6 0.135 -2.15200309344505 Down 0.26528860124158 CG32074 CG32074 - - - - 31672 721.00 39.505 14.955 -1.40140735090068 Down 0.731772553163387 CheA7a chemosensory protein A 7a K12383|1|1e-20|99.8|aga:AgaP_AGAP001184|ganglioside GM2 activator - - - 19834920 473.00 3.315 3.17 -0.0645260299731804 Down 0.0767401928411042 33979 2034.80 1.79 2.375 0.407967925954054 Up 0.224243825122177 sip2 septin interacting protein 2, isoform E - - - - 318997 827.00 0.145 0.01 -3.85798099512757 Down 0.168967111345925 Cpr30F cuticular protein 30F - - GO:0042302//structural constituent of cuticle - 2768994 588.73 70.015 39.12 -0.839757667586421 Down 0.694426099590543 CG33493 CG33493, isoform B - - - - 5740653 8396.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 kl-3 male fertility factor kl3 K10408|1|0.0|1604|smm:Smp_176300|dynein heavy chain, axonemal GO:0030286//dynein complex GO:0016887//ATPase activity;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 37613 678.00 0.355 0.395 0.154033628672421 Up 0.0594703473781535 CG13526 CG13526 K02183|1|2e-25|115|spu:575430|calmodulin - GO:0046872//metal ion binding - 34131 4472.93 37.88 36.845 -0.0399674771475448 Down 0.123464535728437 CG8086 CG8086, isoform P K03006|1|3e-13|78.6|hmg:100204515|DNA-directed RNA polymerase II subunit A [EC:2.7.7.6];K04989|3|4e-11|71.6|rno:100364048|polycystin 1L3 - - - 326221 2131.00 0.095 0.185 0.961525852185364 Up 0.0996235635979395 CG32557 CG32557 K00540|1|2e-32|141|cel:F21D5.3| [EC:1.-.-.-] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0008152//metabolic process 39828 1700.00 2.625 2.195 -0.258096483018127 Down 0.171476687359662 CG4573 CG4573 K01885|1|0.0|1032|dme:Dmel_CG4573|glutamyl-tRNA synthetase [EC:6.1.1.17] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 31247 6822.02 37.895 44.48 0.231149281381919 Up 0.419627526086382 PI4KIIIalpha phosphatidylinositol 4-kinase III alpha, isoform D K00888|1|0.0|4150|dme:Dmel_CG10260|phosphatidylinositol 4-kinase [EC:2.7.1.67] - - - 3355084 2233.00 321.795 350.6 0.123684086230141 Up 0.302106723022058 Snap25 Synaptosomal-associated protein 25kDa, isoform C K08508|1|4e-118|425|dme:Dmel_CG40452|synaptosomal-associated protein, 23kDa GO:0005624//membrane fraction;GO:0016020//membrane GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006904//vesicle docking involved in exocytosis 38019 2267.69 4.46 5.36 0.265189290537468 Up 0.252113327169462 CG6845 CG6845, isoform E - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 37695 3171.00 0.19 0.26 0.452512204697507 Up 0.0833113195086514 CG3502 CG3502 K11140|1|2e-167|590|dse:Dsec_GM12248|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 31370 573.00 0.075 0.4 2.41503749927884 Up 0.223022057852331 CG12691 CG12691 - - - - 19835892 1198.00 3.315 3.22 -0.0419481819979708 Down 0.0640272090873068 317907 1640.27 6.315 17.5 1.47050028293214 Up 0.697331924448554 CG32195 CG32195, isoform C - - - - 32407 3078.94 37.675 43.04 0.192070566071438 Up 0.373134328358209 CG14408 CG14408, isoform H - - - - 34280 2328.00 0.215 0.255 0.246160587269398 Up 0.0625742966583014 gcm2 gcm2 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0042688//crystal cell differentiation;GO:0035163//embryonic hemocyte differentiation;GO:0010001//glial cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent 19834981 602.00 11.265 11.59 0.0410332527710436 Up 0.0951327433628319 42872 1362.00 18.405 20.045 0.12314466776671 Up 0.235768062343152 CG5510 CG5510 K10082|1|9e-177|619|dme:Dmel_CG5510|lectin, mannose-binding 2 GO:0044464//cell part GO:0030246//carbohydrate binding - 36587 1538.13 9.205 7.63 -0.270734664515376 Down 0.320697397965923 SelD Selenide,water dikinase, isoform B K01008|1|0.0|803|dsi:Dsim_GD25689|selenide, water dikinase [EC:2.7.9.3] - GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559 GO:0000097//sulfur amino acid biosynthetic process;GO:0048513//organ development;GO:0000097//sulfur amino acid biosynthetic process;GO:0048513//organ development 3354996 1516.00 22.355 26.28 0.233367729779688 Up 0.390140007924977 CG17168 CG17168 K13108|1|7e-180|630|dme:Dmel_CG17168|smad nuclear-interacting protein 1 - - - 31924 1188.00 0.2 0.19 -0.0740005814437769 Down 0.042365605600317 CG15249 CG15249, isoform D - - - - 36662 1897.34 1.68 2.22 0.402098443571346 Up 0.215526350548144 Cyp6a19 Cyp6a19, isoform B K00517|1|0.0|985|dme:Dmel_CG10243| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 34276 2728.52 90.55 74.48 -0.281861568278736 Down 0.496301677453441 Mtpalpha mitochondrial trifunctional protein alpha subunit, isoform B K07515|1|0.0|1379|dme:Dmel_CG4389|enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process 35665 723.95 50.28 44.47 -0.177152245069 Down 0.364548936732268 sPLA2 secretory phospholipase A2, isoform C K01047|1|3e-113|407|dme:Dmel_CG11124|phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process;GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process;GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 33482 1813.00 0.045 0.03 -0.584962500721156 Down 0.047450799101836 CG18558 CG18558 K00731|1|5e-66|252|cqu:CpipJ_CPIJ003116|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part GO:0016740//transferase activity - 35545 593.00 108.485 264.84 1.28762545749708 Up 0.75683529256373 CG11211 CG11211 K06560|1|7e-12|70.1|tgu:100219050|mannose receptor, C type - GO:0030246//carbohydrate binding - 3772338 534.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 CheA46a chemosensory protein A 46a - - - - 12797949 493.00 0.17 0.47 1.4671260104273 Up 0.199214106458856 CG43138 CG43138 - - - - 38922 561.00 0.875 0.2 -2.12928301694497 Down 0.322975828820499 CG13678 CG13678 - - - - 32709 1508.87 51.06 50.075 -0.0281030217070489 Down 0.10622771100251 CG5162 CG5162, isoform B K01059|1|9e-95|347|dpo:Dpse_GA19044|lipoprotein lipase [EC:3.1.1.34];K01046|3|4e-25|115|rno:117554|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 32766 1309.00 4.705 4.285 -0.134899518616037 Down 0.145522388059701 CG6506 CG6506 K11316|1|3e-179|627|dme:Dmel_CG6506|STAGA complex 65 subunit gamma - - - 40612 920.91 130.09 142.875 0.135243431886685 Up 0.330801743494915 CG2016 CG2016, isoform E - - - - 3772349 3078.08 0.08 0.6 2.90689059560852 Up 0.298210276053362 Tyler tyler, isoform G K03454|1|6e-20|100|dre:406393|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport 31687 3486.96 6.52 9.31 0.513909203327716 Up 0.461761986527539 CG1402 CG1402, isoform C K01672|1|6e-36|152|isc:IscW_ISCW015100|carbonic anhydrase [EC:4.2.1.1] - - - 32625 2424.45 2.345 3.445 0.554916060188915 Up 0.324593844934619 P5CDh2 delta-1-Pyrroline-5-carboxylate dehydrogenase 2, isoform G K00294|1|7e-157|554|dya:Dyak_GE19517|1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.1.12] GO:0031980;GO:0031980;GO:0031980;GO:0031980;GO:0031980;GO:0031980 GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0006560//proline metabolic process;GO:0006560//proline metabolic process;GO:0006560//proline metabolic process;GO:0006560//proline metabolic process;GO:0006560//proline metabolic process;GO:0006560//proline metabolic process 34229 1184.00 0.135 0.075 -0.84799690655495 Down 0.0822546559239202 Rcd-1r Rcd-1 related K12606|1|1e-118|426|dsi:Dsim_GD22367|CCR4-NOT transcription complex subunit 9 - - - 317954 323.00 259.56 8.105 -5.00111207516559 Down 0.900442477876106 Drsl4 Drosomycin-like 4 - - - GO:0006952//defense response 117472 1188.00 0.305 0.165 -0.886343218204433 Down 0.121648395192181 Gr93b gustatory receptor 93b K08471|1|0.0|724|dme:Dmel_CG31336|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 42571 2050.00 34.655 33.91 -0.03135273408289 Down 0.103255844670453 glec gliolectin - GO:0005626//insoluble fraction GO:0005488//binding GO:0048731;GO:0016337//cell-cell adhesion 36011 1869.97 28.425 24.5 -0.214378599889677 Down 0.374554220050192 hebe hebe, isoform F - - - - 41719 1377.00 13.195 14.37 0.123068711131068 Up 0.215064060229824 twf twinfilin K08870|1|0.0|665|der:Dere_GG16839|PTK9 protein tyrosine kinase 9 - - - 39363 1075.00 0.47 0.65 0.467778961350817 Up 0.125016510368511 CG6931 CG6931 - - - - 41720 1200.00 13.37 11.58 -0.207364212104116 Down 0.308809932637696 140up upstream of RpII140, isoform B - - - - 10178923 663.00 0.245 0.405 0.725140158769417 Up 0.125511821423854 CG42753 CG42753 - - - - 39495 4812.00 0.12 0.265 1.14295795384204 Up 0.131554616299036 CG17687 CG17687 - - - - 44228 657.70 241.345 267.45 0.148172265237681 Up 0.352628450667019 Pdsw pdsw, isoform B K03966|1|1e-93|341|dme:Dmel_CG8844|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 10 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain;GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain 32345 1250.00 0.895 0.825 -0.117493563018441 Down 0.0667349095231806 CG10996 CG10996 K01785|1|0.0|790|dme:Dmel_CG10996|aldose 1-epimerase [EC:5.1.3.3] - GO:0005488//binding;GO:0003824//catalytic activity GO:0005996//monosaccharide metabolic process 19835130 832.00 1.465 0.505 -1.53654537167045 Down 0.362105402192577 42987 1272.67 30.71 34.585 0.171437944108524 Up 0.336976621318188 Nmnat nicotinamide mononucleotide adenylyltransferase, isoform C K06210|1|5e-144|510|dsi:Dsim_GD21151|nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] - GO:0070566//adenylyltransferase activity;GO:0070566//adenylyltransferase activity GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0043954//cellular component maintenance;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0043954//cellular component maintenance 37423 1538.00 0.3 0.36 0.263034405833794 Up 0.0724144762911108 CG30391 CG30391 - - - - 35447 1301.00 0.73 0.17 -2.10236171762968 Down 0.293191124025888 CG3635 CG3635, isoform C K01046|1|3e-88|325|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3] - - GO:0044238//primary metabolic process 32365 1165.00 0.375 0.12 -1.64385618977472 Down 0.186269977545899 CG11585 CG11585 K05628|1|8e-08|58.2|mdo:100010925|arginine-glutamic acid dipeptide (RE) repeats;K04705|3|7e-07|55.1|aag:AaeL_AAEL002240|signal transducing adaptor molecule;K05842|4|7e-07|55.1|bta:510427|toll-like receptor adapter molecule 1;K11651|5|1e-06|54.3|aag:AaeL_AAEL010903|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1 - - - 37158 989.00 0.905 4.05 2.16193221068878 Up 0.588330471536125 CG18609 CG18609 K00680|1|3e-59|228|dme:Dmel_CG8534| [EC:2.3.1.-];K10249|5|4e-37|155|isc:IscW_ISCW010886|elongation of very long chain fatty acids protein 4 - - - 39002 3467.92 276.335 195.66 -0.498069455471074 Down 0.64330999867917 Prm paramyosin, isoform E K10352|1|3e-51|204|tca:659358|myosin heavy chain GO:0005859//muscle myosin complex;GO:0005859//muscle myosin complex;GO:0005859//muscle myosin complex;GO:0005859//muscle myosin complex GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity GO:0009888//tissue development;GO:0010927;GO:0009888//tissue development;GO:0010927;GO:0009888//tissue development;GO:0010927;GO:0009888//tissue development;GO:0010927 41847 1539.00 5.39 5.09 -0.0826196166768103 Down 0.108109893012812 CG4334 Zinc/iron regulated transporter-related protein 88E - - - - 31172 920.00 0.175 0.445 1.34645041402143 Up 0.185312376172236 CG14054 CG14054 - - - - 3772456 2647.83 0.79 1.055 0.417318440530082 Up 0.147503632281073 Indy-2 I'm not dead yet 2, isoform B - GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0010259//multicellular organismal aging;GO:0006842//tricarboxylic acid transport;GO:0015711//organic anion transport;GO:0030001//metal ion transport;GO:0010259//multicellular organismal aging;GO:0006842//tricarboxylic acid transport;GO:0015711//organic anion transport;GO:0030001//metal ion transport 33826 1041.00 17.86 17.97 0.0088583283887188 Up 0.0555739004094571 CG13999 CG13999 - - - - 45343 4720.51 4.54 4.295 -0.0800341661524515 Down 0.0990952318055739 pk prickle, isoform C K04511|1|0.0|1384|dme:Dmel_CG11084|prickle GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0009987//cellular process;GO:0051235;GO:0009798//axis specification;GO:0033036;GO:0051234//establishment of localization;GO:0001736//establishment of planar polarity;GO:0009987//cellular process;GO:0051235;GO:0009798//axis specification;GO:0033036;GO:0051234//establishment of localization;GO:0001736//establishment of planar polarity;GO:0009987//cellular process;GO:0051235;GO:0009798//axis specification;GO:0033036;GO:0051234//establishment of localization;GO:0001736//establishment of planar polarity 32685 508.00 0.5 0.225 -1.15200309344505 Down 0.184321754061551 CG13000 CG13000 - - - - 36649 2059.00 0.715 0.975 0.447458976971221 Up 0.149286752080306 CG10202 CG10202 K01840|1|0.0|1269|dme:Dmel_CG10202|phosphomannomutase [EC:5.4.2.8];K01835|5|9e-169|593|aag:AaeL_AAEL001480|phosphoglucomutase [EC:5.4.2.2] - GO:0046872//metal ion binding;GO:0016866//intramolecular transferase activity GO:0044238//primary metabolic process 53472 2404.80 64.155 79.865 0.316001687719475 Up 0.529586580372474 Aplip1 APP-like protein interacting protein 1, isoform B K04434|1|1e-51|204|bta:524806|mitogen-activated protein kinase 8 interacting protein 1 GO:0044424//intracellular part;GO:0044424//intracellular part GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding GO:0048489//synaptic vesicle transport;GO:0008088//axon cargo transport;GO:0043408//regulation of MAPK cascade;GO:0048489//synaptic vesicle transport;GO:0008088//axon cargo transport;GO:0043408//regulation of MAPK cascade 33466 1754.40 17.295 15.83 -0.127693758235747 Down 0.239763571522916 CG3077 CG3077, isoform B - - GO:0005543//phospholipid binding GO:0009987//cellular process 36527 2458.20 35.41 35.355 -0.00224258441959228 Down 0.0441487253995509 fl(2)d female lethal d, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0007538//primary sex determination;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007538//primary sex determination;GO:0000380//alternative mRNA splicing, via spliceosome 40756 1440.16 9.315 26.635 1.51569560661951 Up 0.723913617751948 Osi2 osiris 2, isoform C - - - - 42118 756.00 0.555 0.755 0.443988872974973 Up 0.130167745344076 CG14327 CG14327, isoform B - - - - 19835652 734.00 0.17 0.325 0.934904971778115 Up 0.126568485008585 38578 7180.73 6.625 4.695 -0.496795296684149 Down 0.405461629903579 Gef64C Rho guanine nucleotide exchange factor at 64C, isoform B K07532|1|3e-10|69.3|cfa:479409|Rho guanine nucleotide exchange factor 12 GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction 43622 933.00 0.225 0.95 2.07800251200127 Up 0.331825386342623 Jon99Fi jonah 99Fi K01310|1|1e-124|446|dme:Dmel_CG31362|chymotrypsin [EC:3.4.21.1];K01362|2|1e-124|446|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0032501//multicellular organismal process;GO:0019538//protein metabolic process 41193 1846.00 29.615 29.53 -0.00414672966104435 Down 0.0451393475102364 Snap24 Synaptosomal-associated protein 24kDa K08508|1|2e-117|421|dya:Dyak_GE24734|synaptosomal-associated protein, 23kDa GO:0005624//membrane fraction;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016020//membrane GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006904//vesicle docking involved in exocytosis 36297 542.51 29.375 51.055 0.797463404664854 Up 0.680194161933694 CG18343 CG18343, isoform B - - - - 37983 2769.00 0.645 1.02 0.661198086548241 Up 0.194029850746269 Tpc2 thiamine pyrophosphate carrier protein 2 - - - - 37515 1597.00 23.755 23.44 -0.0192586369885961 Down 0.0774666490556069 CG2921 CG2921 - - - - 37178 1120.00 5.94 6.77 0.188692902774231 Up 0.221371021001189 CG15084 CG15084 K13115|1|1e-168|592|dme:Dmel_CG15084|coiled-coil domain-containing protein 130 - - - 43585 2367.47 2.245 2.32 0.0474093603864253 Up 0.0613855501254788 CG11498 CG11498, isoform C - - - - 43664 3300.52 2.35 2.73 0.216240194354853 Up 0.155692775062739 Ptx1 Ptx1, isoform E K04686|1|2e-44|181|spu:582509|paired-like homeodomain transcription factor 2;K09357|4|2e-43|177|dre:402974|paired-like homeodomain transcription factor 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent 32165 1109.09 260.975 186.865 -0.481915234823653 Down 0.635517104741778 regucalcin regucalcin, isoform D - - GO:0031420;GO:0016301//kinase activity;GO:0031420;GO:0016301//kinase activity GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 19836145 801.00 0.21 0.295 0.490325626583081 Up 0.0927222295601638 39765 4768.74 26.145 26.61 0.0254334401753786 Up 0.095330867784969 Taf4 TBP-associated factor 4, isoform I K03129|1|0.0|1304|dse:Dsec_GM25588|transcription initiation factor TFIID subunit D3 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 36815 465.00 1.245 1.5 0.2688167584278 Up 0.133139611676133 CG15705 CG15705 - - - - 45574 2408.00 2.38 2.105 -0.177141340241547 Down 0.125313697001717 ida imaginal discs arrested K03352|1|0.0|1414|dme:Dmel_CG10850|anaphase-promoting complex subunit 5 GO:0000152//nuclear ubiquitin ligase complex - GO:0007067//mitosis;GO:0006508//proteolysis;GO:0048513//organ development 8674003 973.00 0.455 1.235 1.44057259138598 Up 0.326079778100647 CG42624 CG42624 - GO:0043232 - - 3772638 2882.00 0.22 0.425 0.949959317500404 Up 0.147503632281073 Gr64d gustatory receptor 64d, isoform C K08471|1|0.0|862|dme:Dmel_CG32258|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity - 35635 1667.00 58.425 85.175 0.543844213313521 Up 0.639644696869634 Cyp9b2 cytochrome P450-9b2 K00517|1|0.0|1032|dme:Dmel_CG4486| [EC:1.14.-.-];K07424|3|3e-127|455|dvi:Dvir_GJ14552|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 41494 1690.00 0.05 0.055 0.137503523749935 Up 0.0448421608770308 CG10013 CG10013 - - - - 36763 1865.00 4.435 4.91 0.14678892001363 Up 0.161207238145555 CG8388 CG8388 K09228|1|6e-35|149|mmu:380850|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 38485 2669.90 305.575 316.035 0.0485578246984817 Up 0.160084533086779 CG14989 CG14989, isoform F - - - - 19834859 711.00 5.98 5.43 -0.139193286393744 Down 0.1682076343944 40811 921.00 0.55 0.615 0.16115479181458 Up 0.0673292827895919 sunz sungrazer - - GO:0046872//metal ion binding GO:0007126//meiosis 34637 904.00 0.605 0.245 -1.30415339315939 Down 0.216549993395853 Phae1 phaedra 1, isoform B K01312|1|1e-34|147|bfo:BRAFLDRAFT_88359|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38559 5236.00 9.24 7.345 -0.331130360859777 Down 0.367718927486462 Tie Tie-like receptor tyrosine kinase K08252|1|0.0|1101|dme:Dmel_CG7525|receptor protein-tyrosine kinase [EC:2.7.10.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 41565 1596.00 13.695 12.475 -0.134609450480755 Down 0.226819442609959 Su(fu) suppressor of fused K06229|1|0.0|928|dme:Dmel_CG6054|suppressor of fused - - - 31813 2877.43 11.695 11.785 0.01105989689774 Up 0.053625676925109 Lim1 Lim1, isoform B K09372|1|0.0|928|dme:Dmel_CG11354|LIM homeobox protein 1/5 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process 48782 3585.00 5.65 5.255 -0.104560103340372 Down 0.131587637036059 l(2)35Df lethal (2) 35Df K12598|1|0.0|2045|dme:Dmel_CG4152|ATP-dependent RNA helicase DOB1 [EC:3.6.4.13] GO:0005681//spliceosomal complex GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377 31498 1355.56 31.8 39.03 0.295556697267234 Up 0.483093382644301 CG15772 CG15772, isoform B - - - - 43869 1225.97 12.14 10.53 -0.205262985229965 Down 0.297087570994585 amx almondex, isoform B - GO:0016020//membrane - GO:0009888//tissue development 19835402 387.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 14462361 670.00 40.915 53.755 0.393769100723106 Up 0.56036190727777 32886 3982.32 17.585 19.84 0.174066690761568 Up 0.303229428080835 CG7358 CG7358, isoform C - - - - 43058 1477.00 0.395 0.22 -0.844349129539806 Down 0.136375643904372 CG31097 CG31097 - - - - 41877 1650.49 7.95 7.385 -0.106356939406929 Down 0.157872143706248 CG6136 CG6136, isoform D K06201|1|5e-141|500|dya:Dyak_GE26378|copper homeostasis protein - GO:0046914//transition metal ion binding GO:0055066 36489 839.00 0.19 0.16 -0.247927513443586 Down 0.0579183727380795 Ser8 Ser8 K01312|1|3e-65|248|dpo:Dpse_GA14937|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42578 531.00 7.905 17.125 1.11526662037688 Up 0.664344208162726 fit female-specific independent of transformer - - - - 45282 1975.00 2.66 2.935 0.141934257608862 Up 0.119039756967376 dib disembodied K10721|1|0.0|925|dme:Dmel_CG12028|CYP302A1; ecdysteroid 22-hydroxylase;K00517|3|2e-41|170|dme:Dmel_CG6042| [EC:1.14.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity GO:0008205//ecdysone metabolic process;GO:0048565//digestive tract development;GO:0040003//chitin-based cuticle development;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development 5740574 752.00 0.275 0.01 -4.78135971352466 Down 0.252509576013737 CG34221 CG34221, isoform C - - - - 3772165 2945.23 12.62 13.38 0.084366205658912 Up 0.157409853387928 Pex6 peroxin 6, isoform D K13339|1|0.0|1791|dme:Dmel_CG11919|peroxin-6 GO:0042579//microbody;GO:0042579//microbody GO:0016462//pyrophosphatase activity;GO:0032559;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0008152//metabolic process;GO:0008152//metabolic process 37743 1967.12 23.93 27.74 0.213147390785104 Up 0.372705058776912 St3 sulfotransferase 3, isoform C K01018|1|0.0|633|dme:Dmel_CG5431|tyrosine-ester sulfotransferase [EC:2.8.2.9];K01016|2|2e-32|140|bta:280934|estrone sulfotransferase [EC:2.8.2.4];K01025|4|2e-30|132|hsa:442038| [EC:2.8.2.-];K01014|5|2e-30|132|hsa:445329|aryl sulfotransferase [EC:2.8.2.1] - GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups - 36804 2549.00 0.17 0.26 0.612976876890753 Up 0.094208162726192 krimp krimper - - GO:0046914//transition metal ion binding - 43179 606.32 1.46 1.3 -0.167456745851563 Down 0.0974441949544314 CG31086 CG31086, isoform B - - - - 40012 2074.00 0.635 1.21 0.930178550502429 Up 0.25937788931449 CG5103 CG5103 K00615|1|0.0|1240|dme:Dmel_CG5103|transketolase [EC:2.2.1.1] GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part - GO:0000226//microtubule cytoskeleton organization 19834852 501.00 0.33 0.19 -0.796466605914868 Down 0.119039756967376 36423 688.24 13.875 10.495 -0.402785604832677 Down 0.462422401267996 CG13319 CG13319, isoform B - - - - 30991 4342.00 5.015 5.51 0.135802617958977 Up 0.15975432571655 CG18273 CG18273 - - - - 39203 2476.78 10.9 12.235 0.166685966415101 Up 0.259972262580901 E(z) enhancer of zeste, isoform C K11430|1|0.0|1470|dme:Dmel_CG6502|enhancer of zeste [EC:2.1.1.43] GO:0031519//PcG protein complex;GO:0031519//PcG protein complex GO:0018024//histone-lysine N-methyltransferase activity;GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003676//nucleic acid binding GO:0016458//gene silencing;GO:0048812//neuron projection morphogenesis;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0009058//biosynthetic process;GO:0048513//organ development;GO:0006935//chemotaxis;GO:0034968//histone lysine methylation;GO:0016458//gene silencing;GO:0048812//neuron projection morphogenesis;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0009058//biosynthetic process;GO:0048513//organ development;GO:0006935//chemotaxis;GO:0034968//histone lysine methylation 39487 660.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 CG14115 CG14115 - - - - 33513 2906.00 7.17 6.96 -0.0428858128531765 Down 0.0819904900277374 CG3542 CG3542 K12821|1|0.0|1134|dme:Dmel_CG3542|pre-mRNA-processing factor 40 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0005488//binding GO:0000377 34700 1366.00 15.705 15.79 0.00778722820827205 Up 0.0526350548144235 A16 A16 - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0005488//binding GO:0006325//chromatin organization 32700 864.47 635.23 646.175 0.0246458867200772 Up 0.0938449346189407 RpS5a ribosomal protein S5a, isoform D K02989|1|1e-116|419|dya:Dyak_GE15619|small subunit ribosomal protein S5e GO:0015935//small ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 19836177 437.00 1.57 1.63 0.0541074053394505 Up 0.0566966054682341 - CG45218 - - - - 43556 654.00 14.41 13.53 -0.0909084961982106 Down 0.17203803988905 CG15525 CG15525 K12871|1|9e-86|315|dme:Dmel_CG15525|coiled-coil domain-containing protein 12 - - - 3772011 537.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 CG33643 CG33643 - - - - 35986 1299.00 39.635 26.765 -0.566427323741844 Down 0.61920486065249 Updo updo K01599|1|0.0|716|dsi:Dsim_GD10665|uroporphyrinogen decarboxylase [EC:4.1.1.37] GO:0044424//intracellular part GO:0016831//carboxy-lyase activity GO:0006779//porphyrin-containing compound biosynthetic process 19835879 1359.00 19.675 11.24 -0.807721600173923 Down 0.630134724607053 41765 587.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 CG14852 CG14852 K07515|1|1e-06|52.0|dan:Dana_GF21951|enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211];K06115|3|3e-06|51.2|dre:569585|spectrin beta - - - 19835896 847.22 1.105 1.635 0.565244266106651 Up 0.226555276713776 2768728 1349.00 0.125 0.1 -0.321928094887362 Down 0.0540219257693832 Or46a odorant receptor 46a, isoform B K08471|1|1e-53|210|dme:Dmel_CG33478|gustatory receptor GO:0016020//membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0023052//signaling;GO:0007606//sensory perception of chemical stimulus 19835613 1185.10 94.18 51.27 -0.877305824902232 Down 0.707238145555409 - CG44286, isoform D - - - - 43762 1231.00 0.445 0.435 -0.0327899351176695 Down 0.0416391493858143 CG2053 CG2053, isoform B K12606|1|4e-51|202|bfo:BRAFLDRAFT_284472|CCR4-NOT transcription complex subunit 9 - GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0003006//developmental process involved in reproduction 36258 6895.42 18.785 23.57 0.327370642608396 Up 0.471569145423326 ths thisbe, isoform B - GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0070851//growth factor receptor binding GO:0030154//cell differentiation;GO:0009653//anatomical structure morphogenesis;GO:0009888//tissue development;GO:0048513//organ development;GO:0002164//larval development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 41141 905.00 34.32 33.325 -0.04244467752321 Down 0.122639017302866 mRpL47 mitochondrial ribosomal protein L47 - GO:0000313 GO:0005198//structural molecule activity GO:0010467//gene expression 34707 1693.01 87.725 80.21 -0.129205929999019 Down 0.305937128516709 DnaJ-H DnaJ homolog, isoform C K09503|1|8e-76|285|bta:360006|DnaJ homolog subfamily A member 2 - GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 33530 2221.00 6.695 8.86 0.404222643230708 Up 0.402985074626866 gkt glaikit K10862|1|0.0|1108|dme:Dmel_CG8825|tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] GO:0043231//intracellular membrane-bounded organelle GO:0042578//phosphoric ester hydrolase activity GO:0006259//DNA metabolic process;GO:0007399//nervous system development;GO:0035088//establishment or maintenance of apical/basal cell polarity 5740757 907.00 0.44 0.565 0.360747343777891 Up 0.104543653414344 CG34316 CG34316 - - - - 33221 2580.64 16.985 20.575 0.276631212429787 Up 0.417481178179897 CG4133 CG4133, isoform C - GO:0044464//cell part GO:0046914//transition metal ion binding - 34167 4492.00 26.335 24.035 -0.131844656016061 Down 0.268095363888522 emb embargoed - GO:0005635//nuclear envelope GO:0005515//protein binding;GO:0022892 GO:0032501//multicellular organismal process;GO:0006913//nucleocytoplasmic transport;GO:0007017//microtubule-based process;GO:0006605//protein targeting 32079 1628.00 17.43 15.86 -0.136179798421707 Down 0.252047285695417 Pa1 PTIP associated 1 - - - - 32095 871.40 38.045 39.715 0.0619771408749084 Up 0.163188482366926 Spase25 spase 25-subunit, isoform C K12947|1|3e-109|394|dme:Dmel_CG1751|signal peptidase complex subunit 2 [EC:3.4.-.-] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane GO:0016787//hydrolase activity GO:0051605 39325 4535.37 26.825 31.39 0.226726857938231 Up 0.399451855765421 CG6024 CG6024, isoform F - - - - 43913 1907.79 55.405 56.13 0.0187558817671551 Up 0.0864152687887994 Gyk glycerol kinase, isoform B K00864|1|0.0|945|dme:Dmel_CG18374|glycerol kinase [EC:2.7.1.30] - GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process 34783 4759.93 19.305 17.07 -0.17751149591412 Down 0.310130762118611 CG31731 CG31731, isoform C K05643|1|6e-13|75.9|mdo:100013281|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559 - 318941 876.00 0.58 1.145 0.981222792969372 Up 0.258651433099987 CG31787 CG31787 K01529|1|2e-12|72.8|mcc:709884| [EC:3.6.1.-];K05409|2|3e-11|68.9|ptr:471605|TRIF-related adaptor molecule GO:0031224//intrinsic to membrane - GO:0051234//establishment of localization 41606 1349.00 14.97 9.46 -0.662162132719021 Down 0.571027605336151 CG11668 CG11668 K09640|1|9e-22|104|rno:314636|transmembrane protease, serine 9 [EC:3.4.21.-] - - - 36860 3722.60 64.415 71.91 0.158795729042709 Up 0.347939506009774 CG5065 CG5065, isoform E K13356|1|0.0|1148|dme:Dmel_CG5065|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 19834882 873.00 43.905 37.725 -0.218864345715861 Down 0.407839122969225 37995 760.69 871.405 840.115 -0.0527565650656223 Down 0.162462026152424 RpL19 ribosomal protein L19, isoform B K02885|1|5e-79|293|dvi:Dvir_GJ22263|large subunit ribosomal protein L19e GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 38680 904.00 24.07 29.41 0.289070642412567 Up 0.455752212389381 yip7 yippee interacting protein 7 K01310|1|4e-63|241|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|4|5e-51|201|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35270 651.00 0.01 0.59 5.88264304936184 Up 0.392253335094439 CG13962 CG13962, isoform B - - - - 37080 2626.46 18.9 19.045 0.0110260534549054 Up 0.0581825386342623 Dgp-1 Dgp-1, isoform B K02358|1|5e-11|70.5|cin:100180143|elongation factor EF-Tu [EC:3.6.5.3] - - - 31104 1333.00 0.27 0.23 -0.231325546106456 Down 0.062012944128913 mei-38 meiotic 38, isoform B - - - - 42844 1971.00 2.845 2.75 -0.0489970338945598 Down 0.0634658565579184 Ime4 inducer of meiosis 4 K05925|1|0.0|1187|dme:Dmel_CG5933|mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] GO:0043231//intracellular membrane-bounded organelle GO:0016741 GO:0009451//RNA modification 326151 4352.61 22.56 20.29 -0.152998202642135 Down 0.286884163254524 pgant5 polypeptide GalNAc transferase 5, isoform B K00710|1|0.0|1306|dse:Dsec_GM18035|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process;GO:0009311//oligosaccharide metabolic process 117481 1488.00 0.235 1.24 2.39960745870924 Up 0.393177915731079 Gr64a gustatory receptor 64a K08471|1|0.0|887|dme:Dmel_CG32261|gustatory receptor GO:0031224//intrinsic to membrane GO:0008527//taste receptor activity GO:0034286;GO:0009744//response to sucrose stimulus;GO:0009732;GO:0050909//sensory perception of taste 43739 600.91 633.05 563.925 -0.166816149985136 Down 0.388191784440629 awd abnormal wing discs, isoform E K00940|1|7e-96|349|dya:Dyak_GE23305|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0005874//microtubule GO:0032561//guanyl ribonucleotide binding;GO:0046872//metal ion binding;GO:0032559;GO:0015631//tubulin binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor GO:0009209;GO:0007163//establishment or maintenance of cell polarity;GO:0007424//open tracheal system development;GO:0006468//protein phosphorylation;GO:0009206;GO:0009132//nucleoside diphosphate metabolic process;GO:0045216//cell-cell junction organization 43693 1162.37 2178.395 2203.985 0.0168488290441445 Up 0.0941421212521464 CG1746 CG1746, isoform G K02128|1|2e-45|184|der:Dere_GG11879|F-type H+-transporting ATPase subunit c [EC:3.6.3.14] GO:0031224//intrinsic to membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0031224//intrinsic to membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0031224//intrinsic to membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 19836194 455.00 0.105 0.225 1.09953567355091 Up 0.117718927486461 19835187 720.00 0.06 0.125 1.05889368905357 Up 0.0856557918372738 41453 1277.12 12.87 10.135 -0.344665964753803 Down 0.418504821027605 CG12224 CG12224, isoform C K04883|1|3e-06|52.8|gga:396068|potassium voltage-gated channel Shaker-related subfamily A, beta member 2 - GO:0003824//catalytic activity GO:0030001//metal ion transport;GO:0008152//metabolic process 10178860 496.00 0.25 0.375 0.584962500721156 Up 0.11005811649716 CG42790 CG42790, isoform C - - - - 32733 1561.43 1.295 1.45 0.163100802328381 Up 0.096420552106723 CG12992 CG12992, isoform E - - - - 39858 2037.71 48.135 50.925 0.0812877848502865 Up 0.204200237749307 Mo25 Mo25, isoform B K08272|1|3e-179|628|dya:Dyak_GE22202|calcium binding protein 39 - - - 246668 528.00 5.425 3.89 -0.47985298234565 Down 0.366232994320433 Obp56f Odorant-binding protein 56f - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 3771908 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33905 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 34068 6029.61 12.785 10.97 -0.220888634838456 Down 0.315513142253335 LanB1 LanB1, isoform B K06243|1|0.0|1436|xla:494988|laminin, beta 2;K05636|2|0.0|1401|mmu:16777|laminin, beta 1 GO:0044464//cell part;GO:0005578//proteinaceous extracellular matrix;GO:0044464//cell part;GO:0005578//proteinaceous extracellular matrix GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0048870//cell motility;GO:0009653//anatomical structure morphogenesis;GO:0071711//basement membrane organization;GO:0048870//cell motility;GO:0009653//anatomical structure morphogenesis;GO:0071711//basement membrane organization 49713 3007.00 25.005 28.54 0.19076872976819 Up 0.351109496763968 alpha-catenin-related alpha-catenin related, isoform C K12597|1|3e-150|532|tca:658111|protein AIR1/2;K05691|2|2e-17|91.3|xla:444710|catenin (cadherin-associated protein), alpha GO:0005856//cytoskeleton - GO:0009987//cellular process 37644 1335.99 1.99 2.46 0.305889884795591 Up 0.191091005151235 CG3788 CG3788, isoform B K00757|1|0.0|715|dme:Dmel_CG3788|uridine phosphorylase [EC:2.4.2.3] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 33763 637.09 31.87 22.37 -0.510633762718734 Down 0.588561616695285 CG14022 CG14022, isoform B K01512|1|1e-54|212|dya:Dyak_GE19003|acylphosphatase [EC:3.6.1.7] GO:0043231//intracellular membrane-bounded organelle GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides - 14462513 683.00 7.435 7.965 0.099341619472891 Up 0.148692378813895 37007 4200.15 33.955 27.415 -0.30865855868722 Down 0.482895258222164 Sema-1b Sema-1b, isoform C K06842|1|6e-166|585|cqu:CpipJ_CPIJ000027|semaphorin 6 GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity GO:0006935//chemotaxis;GO:0009792//embryo development ending in birth or egg hatching 36626 831.50 19.69 18.33 -0.103256325361668 Down 0.205884295337472 CG10139 CG10139, isoform B - - - - 318940 1487.00 1.285 2.28 0.827265464970864 Up 0.332320697397966 CG31785 CG31785 - - - - 5740349 7057.27 11.245 14.32 0.34874783148644 Up 0.435840707964602 CG34357 CG34357, isoform D K01769|1|7e-161|567|dme:Dmel_CG34357|guanylate cyclase, other [EC:4.6.1.2] - GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0032559 GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0023033 326205 4644.00 0.74 0.49 -0.594743521513742 Down 0.15153216219786 Claspin claspin, isoform B K04574|1|3e-06|55.5|hsa:4744|neurofilament heavy polypeptide;K04572|3|1e-05|53.5|dre:793912|neurofilament light polypeptide - - - 3771905 5551.12 17.595 18.86 0.100164161925432 Up 0.202549200898164 CG43736 CG43736, isoform L - - - - 42506 591.00 0.415 0.93 1.16411937976111 Up 0.257099458459913 Obp93a Odorant-binding protein 93a - - GO:0005488//binding GO:0051234//establishment of localization 39352 1146.00 2.525 3.065 0.279603686051624 Up 0.198454629507331 CG5883 CG5883 - - GO:0030247//polysaccharide binding GO:0006022 47396 7985.10 6.065 7.14 0.235416428908589 Up 0.264430062078986 Tor target of rapamycin, isoform B K07203|1|0.0|4767|dme:Dmel_CG5092|FKBP12-rapamycin complex-associated protein GO:0016020//membrane GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0045165//cell fate commitment;GO:0045137//development of primary sexual characteristics;GO:0010259//multicellular organismal aging;GO:0006796//phosphate-containing compound metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003002//regionalization;GO:0045927//positive regulation of growth;GO:0016197//endosomal transport;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0048598//embryonic morphogenesis;GO:0007584//response to nutrient;GO:0042254//ribosome biogenesis;GO:0044248//cellular catabolic process 34117 2660.00 28.82 37.855 0.393413532698213 Up 0.544511953506802 CG8451 Sodium/solute co-transporter-like 5A11 K03307|1|4e-111|402|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport 32947 3097.00 12.915 16.055 0.31397502160777 Up 0.422104081363096 car carnation, isoform C - GO:0000323//lytic vacuole;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0044446//intracellular organelle part;GO:0000323//lytic vacuole;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0044446//intracellular organelle part GO:0005515//protein binding;GO:0005515//protein binding GO:0048753//pigment granule organization;GO:0016236//macroautophagy;GO:0048069//eye pigmentation;GO:0006623//protein targeting to vacuole;GO:0007033//vacuole organization;GO:0010259//multicellular organismal aging;GO:0007041//lysosomal transport;GO:0016567//protein ubiquitination;GO:0048278//vesicle docking;GO:0048753//pigment granule organization;GO:0016236//macroautophagy;GO:0048069//eye pigmentation;GO:0006623//protein targeting to vacuole;GO:0007033//vacuole organization;GO:0010259//multicellular organismal aging;GO:0007041//lysosomal transport;GO:0016567//protein ubiquitination;GO:0048278//vesicle docking 40993 656.00 20.41 22.875 0.164495561026048 Up 0.301413287544578 Arf84F ADP ribosylation factor-like 2 K07943|1|1e-95|348|dme:Dmel_CG7435|ADP-ribosylation factor-like 2 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0004857//enzyme inhibitor activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0006836//neurotransmitter transport;GO:0043623//cellular protein complex assembly;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0006464//cellular protein modification process 3771856 582.00 2.185 0.65 -1.74912165647214 Down 0.452813366794347 CheA84a chemosensory protein A 84a - - - - 19834821 650.00 2.43 1.8 -0.432959407276106 Down 0.236758684453837 31748 1430.00 0.43 1.06 1.3016556998611 Up 0.289955091797649 CG15337 CG15337 - - - - 36289 3532.00 3.735 3.585 -0.0591351240873325 Down 0.0767401928411042 RpIII128 RNA polymerase III 128kD subunit K03021|1|0.0|2220|dme:Dmel_CG8344|DNA-directed RNA polymerase III subunit C2 [EC:2.7.7.6] GO:0044451//nucleoplasm part GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0001882//nucleoside binding GO:0006351//transcription, DNA-dependent;GO:0031016//pancreas development 38099 6210.60 0.23 0.55 1.25779775746765 Up 0.201261392154273 CG13889 CG13889, isoform B K11499|1|6e-22|107|spu:592172|centromere protein F;K09291|4|2e-18|95.9|gga:424457|nucleoprotein TPR - GO:0005488//binding - 38341 1320.00 37.4 40.4 0.111317022864158 Up 0.253004887069079 CG1240 putative nucleolar protein 2 - - - - 33678 1280.00 361.865 224.075 -0.691469878681984 Down 0.693138290846652 Clect27 C-type lectin 27kD, isoform B - - GO:0030246//carbohydrate binding - 31604 722.15 133.755 145.65 0.122912878447643 Up 0.295634658565579 CG3192 CG3192, isoform C K03964|1|5e-105|381|dme:Dmel_CG3192|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 [EC:1.6.5.3 1.6.99.3] - - - 39077 854.74 91.655 55.85 -0.714656304676807 Down 0.680689472989037 Hsp23 heat shock protein 23, isoform B K09542|1|1e-22|107|dme:Dmel_CG4533|crystallin, alpha B;K04455|2|6e-21|101|tgu:100225266|heat shock 27kDa protein 1 GO:0015630//microtubule cytoskeleton GO:0008092//cytoskeletal protein binding GO:0006950//response to stress 33413 721.00 0.17 0.065 -1.38702312310925 Down 0.109694888389909 CG16995 CG16995 - - - - 39032 1710.62 31.62 34.32 0.118212185141175 Up 0.262911108175934 CG5068 CG5068, isoform B K13617|1|0.0|767|dme:Dmel_CG5068|protein phosphatase methylesterase 1 [EC:3.1.1.-] - - - 39796 646.00 254.815 70.735 -1.84895405723323 Down 0.783747193237353 CG13043 CG13043 - - - - 37184 449.00 63.545 119.145 0.906867891912039 Up 0.714998018755779 DptB diptericin B - - - - 12798414 840.00 0.58 0.13 -2.15754127698648 Down 0.261458195746929 CG43336 CG43336 - - - - 39927 1653.00 0.03 0.03 0 - 0.0382380134724607 CG13724 CG13724 - - - - 40410 5063.00 16.475 18.485 0.166076578291829 Up 0.294247787610619 CG7158 CG7158 K04575|1|0.0|2821|dme:Dmel_CG7158|amyotrophic lateral sclerosis 2 (juvenile) - - - 33768 6461.02 0.82 0.885 0.110053545464914 Up 0.0625082551842557 nompC no mechanoreceptor potential C, isoform F K10380|1|2e-97|358|tca:100142605|ankyrin GO:0031224//intrinsic to membrane;GO:0042995//cell projection;GO:0031224//intrinsic to membrane;GO:0042995//cell projection;GO:0031224//intrinsic to membrane;GO:0042995//cell projection GO:0008092//cytoskeletal protein binding;GO:0005261//cation channel activity;GO:0008092//cytoskeletal protein binding;GO:0005261//cation channel activity;GO:0008092//cytoskeletal protein binding;GO:0005261//cation channel activity GO:0070838//divalent metal ion transport;GO:0009612//response to mechanical stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0050906//detection of stimulus involved in sensory perception;GO:0070838//divalent metal ion transport;GO:0009612//response to mechanical stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0050906//detection of stimulus involved in sensory perception;GO:0070838//divalent metal ion transport;GO:0009612//response to mechanical stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0050906//detection of stimulus involved in sensory perception 12798242 325.00 0.575 0.695 0.273451021779132 Up 0.0937458724078721 CG43184 CG43184 - - - - 42737 2370.00 0.87 0.475 -0.873087887517781 Down 0.212983753797385 hh hedgehog K06224|1|0.0|826|dme:Dmel_CG4637|hedgehog GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016020//membrane;GO:0044421//extracellular region part GO:0005102//receptor binding;GO:0004175//endopeptidase activity GO:0035215//genital disc development;GO:0001745//compound eye morphogenesis;GO:0007424//open tracheal system development;GO:0030908//protein splicing;GO:0002009//morphogenesis of an epithelium;GO:0000904//cell morphogenesis involved in differentiation;GO:0021537//telencephalon development;GO:0042307//positive regulation of protein import into nucleus;GO:0003399;GO:0040008//regulation of growth;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0035161;GO:0008354//germ cell migration;GO:0000278//mitotic cell cycle;GO:0007560//imaginal disc morphogenesis;GO:0000578//embryonic axis specification;GO:0007281//germ cell development;GO:0007267//cell-cell signaling;GO:0008283//cell proliferation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007227//signal transduction downstream of smoothened;GO:0048645//organ formation;GO:0007365//periodic partitioning;GO:0017145//stem cell division;GO:0043704//photoreceptor cell fate specification;GO:0035287//head segmentation;GO:0008589//regulation of smoothened signaling pathway;GO:0006355//regulation of transcription, DNA-dependent 33003 6557.32 8.105 8.61 0.0872010518793023 Up 0.140503236032228 pico pico, isoform D - - - - 41816 4179.47 57.61 36.525 -0.657434984788369 Down 0.656980583806631 CG6966 CG6966, isoform C K10349|1|7e-81|302|tca:664462|Fem-1 homolog b - - - 40928 5103.36 72.25 89.545 0.309615289862095 Up 0.523477744023247 CG17816 CG17816, isoform K - - - - 3355131 2487.40 21.83 22.895 0.0687204346827563 Up 0.162792233522652 cta concertina, isoform B K04346|1|3e-102|373|spu:414055|guanine nucleotide binding protein (G protein), alpha 12;K04639|3|1e-100|367|mmu:14674|guanine nucleotide binding protein (G protein), alpha 13 GO:0019897//extrinsic to plasma membrane GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0008360//regulation of cell shape;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0010004//gastrulation involving germ band extension 40558 1178.00 30.035 30.81 0.0367540185128817 Up 0.118313300752873 CG14647 CG14647 - GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005267//potassium channel activity GO:0030001//metal ion transport 36518 2503.82 1.09 1.825 0.743568328990453 Up 0.284572711662924 CG13337 CG13337, isoform B - - - - 38895 5078.97 88.05 80.405 -0.131037785601109 Down 0.306234315149914 Ect4 Ectoderm-expressed 4, isoform K - GO:0044425//membrane part;GO:0044425//membrane part;GO:0044425//membrane part;GO:0044425//membrane part;GO:0044425//membrane part GO:0004872//receptor activity;GO:0004872//receptor activity;GO:0004872//receptor activity;GO:0004872//receptor activity;GO:0004872//receptor activity GO:0006952//defense response;GO:0023060;GO:0006952//defense response;GO:0023060;GO:0006952//defense response;GO:0023060;GO:0006952//defense response;GO:0023060;GO:0006952//defense response;GO:0023060 38661 1688.00 0.415 0.565 0.445139531068263 Up 0.113888521991811 Pole2 Pole2 K02325|1|0.0|1064|dme:Dmel_CG10489|DNA polymerase epsilon subunit 2 [EC:2.7.7.7] GO:0000109//nucleotide-excision repair complex GO:0003676//nucleic acid binding;GO:0034061 GO:0006260//DNA replication;GO:0033554//cellular response to stress 19835920 2517.00 67.985 15.78 -2.10711926435313 Down 0.779718663320565 326256 1067.00 11.755 13.285 0.176523688837485 Up 0.277308149517897 CG33107 CG33107 - - - - 318880 662.00 0.55 0.405 -0.441509710640035 Down 0.113426231673491 CG31677 CG31677 - - - - 14462756 757.00 1.165 1.41 0.275365207744513 Up 0.132479196935676 38241 1083.55 231.015 98.43 -1.23081653040589 Down 0.750429269581297 Cpr62Bc cuticular protein 62Bc, isoform B - - GO:0005198//structural molecule activity - 33658 2729.00 6.955 8.4 0.272338813123883 Up 0.309866596222428 CG17840 CG17840 K01099|1|3e-32|140|bfo:BRAFLDRAFT_62034|phosphatidylinositol-bisphosphatase [EC:3.1.3.36] - - - 35042 2490.25 127.165 154.545 0.281325331363238 Up 0.506273940034342 CLIP-190 cytoplasmic linker protein 190, isoform V K10421|1|6e-69|263|ptr:467147|CAP-Gly domain-containing linker protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process;GO:0007275//multicellular organismal development;GO:0009987//cellular process 31708 1317.26 12.445 12.18 -0.0310520970747035 Down 0.0834434024567428 CG10778 CG10778, isoform B K11778|1|4e-173|607|dme:Dmel_CG10778|cis-prenyltransferase, dehydrodolichyl diphosphate synthase [EC:2.5.1.-] - - - 38812 3499.64 6.91 5.15 -0.424113278317678 Down 0.377625148593317 eco eco, isoform B K11268|1|0.0|1916|dme:Dmel_CG8598|N-acetyltransferase [EC:2.3.1.-] GO:0000785//chromatin;GO:0000785//chromatin GO:0016407//acetyltransferase activity;GO:0003677//DNA binding;GO:0034061;GO:0016407//acetyltransferase activity;GO:0003677//DNA binding;GO:0034061 GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process 8674049 7561.39 123.7 124.215 0.00599390125481653 Up 0.0669000132082948 Pif1A PFTAIRE-interacting factor 1A, isoform I K11499|1|3e-08|62.4|spu:592172|centromere protein F;K09291|2|3e-08|62.4|cin:100185005|nucleoprotein TPR;K10352|4|6e-08|61.2|dre:561431|myosin heavy chain;K04514|5|8e-08|60.8|bta:785911|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity - 31763 4165.16 11.815 13.97 0.241712391435616 Up 0.343118478404438 CG1632 CG1632, isoform B K09614|1|1e-40|169|cfa:482135|corin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0007166//cell surface receptor signaling pathway;GO:0032501//multicellular organismal process;GO:0019538//protein metabolic process 318249 437.65 38.985 32.675 -0.254731898510561 Down 0.433925505217276 mRpS21 mitochondrial ribosomal protein S21, isoform B - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 31398 696.00 40.115 40.255 0.00502619161418274 Up 0.0576542068418967 mRpL30 mitochondrial ribosomal protein L30 - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 32798 947.00 0.335 0.465 0.473069620650259 Up 0.107647602694492 Andorra andorra - - - - 40706 1051.00 3.51 5.18 0.561481067381993 Up 0.391262712983754 CG1239 CG1239, isoform C - GO:0044424//intracellular part GO:0016423//tRNA (guanine) methyltransferase activity GO:0006629//lipid metabolic process;GO:0008213;GO:0008033//tRNA processing 42795 7098.00 43.44 54.17 0.318469987666691 Up 0.516081098930128 VAChT VAChT K08155|1|4e-74|281|dmo:Dmoj_GI21330|MFS transporter, DHA1 family, solute carrier family 18 (vesicular monoamine) GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity GO:0006810//transport 41529 1365.00 24.19 26.975 0.157212190395454 Up 0.309173160744948 CG5641 CG5641 K13089|1|0.0|707|dme:Dmel_CG5641|interleukin enhancer-binding factor 2 - - - 43212 1031.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 Tb tubby - - - - 33500 2477.97 3.98 5.56 0.482316452179859 Up 0.371021001188747 Rrp1 recombination repair protein 1, isoform B K10771|1|0.0|1099|dme:Dmel_CG3178|AP endonuclease 1 [EC:4.2.99.18] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0016835//carbon-oxygen lyase activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0016835//carbon-oxygen lyase activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0008296//3'-5'-exodeoxyribonuclease activity GO:0014909//smooth muscle cell migration;GO:0034614//cellular response to reactive oxygen species;GO:0003143//embryonic heart tube morphogenesis;GO:0019725//cellular homeostasis;GO:0006915//apoptotic process;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0009725//response to hormone stimulus;GO:0003015//heart process;GO:0008152//metabolic process;GO:0014909//smooth muscle cell migration;GO:0034614//cellular response to reactive oxygen species;GO:0006259//DNA metabolic process;GO:0003143//embryonic heart tube morphogenesis;GO:0019725//cellular homeostasis;GO:0006915//apoptotic process;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0009725//response to hormone stimulus;GO:0003015//heart process 32269 1947.74 10.365 11.115 0.100787831917575 Up 0.171179500726456 CG12096 CG12096, isoform C K06692|1|1e-45|184|tca:657550|26S proteasome non-ATPase regulatory subunit 5 - - - 38106 1303.00 21.475 9.36 -1.19807769644242 Down 0.686897371549333 CG34056 CG34056 K00731|1|3e-68|259|dya:Dyak_GE10709|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part GO:0008378//galactosyltransferase activity GO:0006464//cellular protein modification process 42586 1806.20 195.24 190.53 -0.0352304809437823 Down 0.136078457271166 CG6439 CG6439, isoform B K00030|1|0.0|678|dme:Dmel_CG6439|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0009060//aerobic respiration;GO:0009060//aerobic respiration 37566 1710.00 0.075 0.065 -0.206450877467427 Down 0.045898824461762 ppk12 pickpocket 12 K04832|1|3e-98|359|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04828|2|1e-17|91.3|gga:419945|amiloride-sensitive cation channel 1, neuronal (degenerin) GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 41151 1039.22 19.36 17.95 -0.109095108564181 Down 0.217606656980584 MBD-like MBD-like, isoform C K11590|1|2e-117|422|dpo:Dpse_GA20899|methyl-CpG-binding domain protein 2 GO:0000118//histone deacetylase complex;GO:0005694//chromosome;GO:0000118//histone deacetylase complex;GO:0005694//chromosome GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0000166//nucleotide binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0000166//nucleotide binding GO:0006355//regulation of transcription, DNA-dependent;GO:0032501//multicellular organismal process;GO:0006355//regulation of transcription, DNA-dependent;GO:0032501//multicellular organismal process 42242 2404.00 3.445 2.475 -0.477075457737319 Down 0.297120591731607 CG7702 CG7702, isoform B K13023|1|2e-17|91.3|bta:614562|carboxypeptidase N regulatory subunit;K06260|2|6e-17|89.7|bta:522692|platelet glycoprotein V - GO:0005488//binding;GO:0005488//binding - 14462891 798.00 46.1 43.975 -0.0680831729573773 Down 0.182472592788271 34734 2146.00 26.645 22.24 -0.260708045036527 Down 0.419297318716154 Drep-4 DNA fragmentation factor-related protein 4 K02311|1|0.0|729|dpo:Dpse_GA21770|DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-];K00555|2|2e-41|171|tca:654887|tRNA (guanine-N2-)-methyltransferase [EC:2.1.1.32] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0003824//catalytic activity GO:0000737//DNA catabolic process, endonucleolytic;GO:0012501//programmed cell death 37500 2667.79 13.47 12.32 -0.128747594767402 Down 0.221833311319509 CG9304 CG9304, isoform B - GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 34476 1191.00 0.185 0.075 -1.30256277002043 Down 0.114284770836085 CG6431 CG6431, isoform C K01046|1|3e-24|112|nvi:100119257|triacylglycerol lipase [EC:3.1.1.3];K12591|2|2e-23|109|nvi:100113631|exosome complex exonuclease RRP6 [EC:3.1.13.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 246638 546.00 22.145 21.425 -0.0476857928854541 Down 0.127691190067362 ave aveugle - GO:0016020//membrane;GO:0044424//intracellular part - GO:0001745//compound eye morphogenesis;GO:0023060;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 32928 5276.85 34.775 47.285 0.443332081953687 Up 0.580438515387663 gfA nicotinic acetylcholine receptor alpha7, isoform F K04809|1|4e-129|462|gga:374001|nicotinic acetylcholine receptor alpha-7 GO:0030425//dendrite;GO:0005887//integral to plasma membrane;GO:0030425//dendrite;GO:0005887//integral to plasma membrane;GO:0030425//dendrite;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0051899//membrane depolarization;GO:0007610//behavior;GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0051899//membrane depolarization;GO:0007610//behavior;GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0051899//membrane depolarization;GO:0007610//behavior 50121 561.00 0.435 0.085 -2.35548065459839 Down 0.234117025492009 CG11666 CG11666 - - - - 40384 3371.00 5.35 5.635 0.0748767188837118 Up 0.103189803196407 SAK Sak kinase K08863|1|0.0|1556|dme:Dmel_CG7186|polo-like kinase 4 [EC:2.7.11.21] GO:0005813//centrosome GO:0004672//protein kinase activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0051297//centrosome organization;GO:0003006//developmental process involved in reproduction;GO:0006464//cellular protein modification process 35323 1477.00 17.245 20.475 0.247685323067518 Up 0.387729494122309 CG2608 CG2608 - - - - 14462610 291.00 0.16 0.18 0.169925001442312 Up 0.0510500594373266 5740130 603.00 38.98 15.345 -1.34496544479141 Down 0.728272355038964 CG34454 CG34454 - - GO:0004866//endopeptidase inhibitor activity GO:0006508//proteolysis 3771936 268.00 0.01 0.465 5.53915881110803 Up 0.347444194954431 34136 1156.00 8.14 9.23 0.181301853379527 Up 0.244716682076344 CG7840 CG7840 K12345|1|0.0|666|dme:Dmel_CG7840|3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.99.5] GO:0044424//intracellular part;GO:0031224//intrinsic to membrane GO:0016491//oxidoreductase activity GO:0044238//primary metabolic process 246432 671.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 Obp50a Odorant-binding protein 50a, isoform B - - - - 39156 1561.37 30.295 35.525 0.229754943903201 Up 0.408103288865407 I-2 Inhibitor-2, isoform B - - GO:0019212//phosphatase inhibitor activity;GO:0019212//phosphatase inhibitor activity GO:0010921//regulation of phosphatase activity;GO:0007165//signal transduction;GO:0006470//protein dephosphorylation;GO:0010921//regulation of phosphatase activity;GO:0007165//signal transduction;GO:0006470//protein dephosphorylation 44787 1134.75 56.555 27.03 -1.06509306594682 Down 0.716649055606921 miple2 miple2, isoform G - - GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding - 50267 402.00 107.71 237.94 1.14344562441332 Up 0.744749702813367 CG13056 CG13056 - - - - 34752 1009.78 17.13 16.745 -0.0327947753772831 Down 0.091566503764364 CG9293 CG9293, isoform B K11345|1|7e-119|426|dme:Dmel_CG9293|inhibitor of growth protein 5 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 43223 3536.50 30.8 35.98 0.224264835669219 Up 0.399154669132215 Lerp lysosomal enzyme receptor protein, isoform E K06564|1|0.0|1688|dme:Dmel_CG31072|insulin-like growth factor 2 receptor GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0048193//Golgi vesicle transport;GO:0007034//vacuolar transport;GO:0048193//Golgi vesicle transport;GO:0007034//vacuolar transport;GO:0048193//Golgi vesicle transport;GO:0007034//vacuolar transport 41345 1909.00 11.265 12.17 0.1114818544783 Up 0.188911636507727 CG6689 CG6689 K09228|1|7e-35|149|mmu:436100|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19835445 601.00 0.345 0.01 -5.10852445677817 Down 0.295898824461762 41512 919.82 4.66 3.795 -0.296230069238814 Down 0.256736230352661 GstD11 glutathione S transferase D11, isoform B K00799|1|6e-129|459|dme:Dmel_CG17639|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0006790//sulfur compound metabolic process 37589 646.00 649.275 632.78 -0.0371256583021232 Down 0.139743759080703 RpS24 ribosomal protein S24 K02974|1|2e-51|201|dya:Dyak_GE11854|small subunit ribosomal protein S24e GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex GO:0005488//binding;GO:0005198//structural molecule activity GO:0010467//gene expression 31538 3922.55 2.795 2.98 0.0924640476189716 Up 0.0906419231277242 CG5921 CG5921, isoform E K10692|1|1e-09|65.5|dre:561226|E3 ubiquitin-protein ligase LNX1 [EC:6.3.2.19];K12076|2|5e-09|63.5|ssc:100157729|disks large protein 1;K12075|3|9e-09|62.8|spu:592591|discs large protein - - - 38210 2145.00 0.09 0.025 -1.84799690655495 Down 0.0883634922731475 CG13930 CG13930 K10409|1|1e-23|111|ptr:465060|dynein intermediate chain 1, axonemal GO:0005875//microtubule associated complex - - 19835508 542.00 0.085 0.09 0.082462160191973 Up 0.0426627922335227 41840 2367.73 845.995 801.9 -0.0772267984514453 Down 0.225993924184388 Hsc70-4 heat shock protein cognate 4, isoform G K03283|1|0.0|1125|dya:Dyak_GE24282|heat shock 70kDa protein 1/8 - - - 34776 2316.00 1.325 2.385 0.84799690655495 Up 0.343745872407872 CG7311 CG7311, isoform E K00111|1|0.0|1243|dme:Dmel_CG7311|glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor GO:0006071//glycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0022904//respiratory electron transport chain 33700 2888.00 37.975 38.58 0.0228031786596577 Up 0.084731211200634 hoe2 hoepel2 - GO:0031224//intrinsic to membrane GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006842//tricarboxylic acid transport 19835144 636.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 39123 910.00 215.89 334.85 0.633218548610591 Up 0.681085721833311 CG8329 CG8329 K01310|1|4e-92|337|dme:Dmel_CG18179|chymotrypsin [EC:3.4.21.1];K01362|3|3e-56|218|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41985 1076.00 0.615 0.145 -2.08453351021167 Down 0.267831197992339 CG42446 CG42446 - - - - 42858 2174.00 15.975 13.62 -0.230089227822286 Down 0.347642319376568 CG13605 CG13605 K10667|1|4e-08|60.5|nve:NEMVE_v1g197820|E3 ubiquitin-protein ligase RNF8 [EC:6.3.2.19];K10601|2|6e-08|59.7|dan:Dana_GF22986|E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 33015 2345.35 0.38 0.53 0.479992941119614 Up 0.114548936732268 Phf7 PHD finger protein 7 ortholog, isoform C - - GO:0005488//binding - 32176 811.00 0.1 0.12 0.263034405833794 Up 0.0530973451327434 CG12721 CG12721 - - - - 40966 2442.03 9.82 10.67 0.119765246509732 Up 0.191454233258486 Ada2b transcriptional adaptor 2b, isoform C K11314|1|3e-30|134|tgu:100222358|transcriptional adapter 2-alpha GO:0070461//SAGA-type complex;GO:0005694//chromosome;GO:0070461//SAGA-type complex;GO:0005694//chromosome GO:0046914//transition metal ion binding;GO:0004468//lysine N-acetyltransferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0004468//lysine N-acetyltransferase activity;GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0007154//cell communication;GO:0043324;GO:0007447//imaginal disc pattern formation;GO:0016573//histone acetylation;GO:0010468//regulation of gene expression;GO:0007154//cell communication;GO:0043324;GO:0007447//imaginal disc pattern formation;GO:0016573//histone acetylation 40180 5316.69 17.235 19.18 0.154261421650861 Up 0.276218465196143 Ac76E adenylyl cyclase 76E, isoform B K08042|1|0.0|2145|dme:Dmel_CG7978|adenylate cyclase 2 [EC:4.6.1.1] - GO:0005488//binding;GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process 35105 1927.68 86.225 43.39 -0.990743637531473 Down 0.716880200766081 CG10178 CG10178, isoform B K00699|1|0.0|1073|dme:Dmel_CG10178|glucuronosyltransferase [EC:2.4.1.17] - GO:0005506//iron ion binding;GO:0016209//antioxidant activity;GO:0016757//transferase activity, transferring glycosyl groups GO:0008152//metabolic process;GO:0006950//response to stress 5740816 4114.38 8.11 11.31 0.479825109772548 Up 0.475267467969885 CG34391 CG34391, isoform E K06774|1|2e-25|117|xla:444598|neurotrimin - GO:0030247//polysaccharide binding GO:0006022 53552 940.00 0.46 0.42 -0.131244533278253 Down 0.0577532690529653 lectin-21Ca lectin-21Ca K06563|1|4e-06|52.0|mmu:170780|CD209 antigen;K06560|2|6e-06|51.6|hmg:100206932|mannose receptor, C type - - - 317887 2517.00 12.09 9.815 -0.300754071782952 Down 0.380464931977282 l(3)72Dp lethal (3) 72Dp K01307|1|0.0|675|dme:Dmel_CG32155|gamma-glutamyl hydrolase [EC:3.4.19.9] - GO:0008238//exopeptidase activity GO:0009064//glutamine family amino acid metabolic process 12798537 1090.00 12.685 16.27 0.359090731608589 Up 0.456511689340906 36317 1989.00 8.975 3.855 -1.21918107879538 Down 0.614879144102496 Cyp6g2 Cyp6g2 K00517|1|0.0|1045|dme:Dmel_CG8859| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 45041 1294.00 0.96 0.925 -0.0535810402048439 Down 0.0483423590014529 Spn43Aa serpin 43Aa K13963|1|6e-68|258|aga:AgaP_AGAP005246|serpin B - GO:0004866//endopeptidase inhibitor activity - 37669 422.00 0.01 0.23 4.52356195605701 Up 0.229362039360719 RpL37b ribosomal protein L37b K02922|1|7e-49|191|dme:Dmel_CG9873|large subunit ribosomal protein L37e GO:0015934//large ribosomal subunit GO:0043169//cation binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 41937 955.50 20.31 21.37 0.0733966683636583 Up 0.162462026152424 blp black pearl, isoform B - - - - 31391 6862.82 2.265 4.03 0.831268788481732 Up 0.426991150442478 peb pebbled, isoform B K09228|1|4e-12|75.5|cfa:486142|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding GO:0042461//photoreceptor cell development;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009880//embryonic pattern specification;GO:0043409//negative regulation of MAPK cascade;GO:0007424//open tracheal system development;GO:0007320//insemination;GO:0010468//regulation of gene expression;GO:0001736//establishment of planar polarity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010669//epithelial structure maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0035028;GO:0042461//photoreceptor cell development;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009880//embryonic pattern specification;GO:0043409//negative regulation of MAPK cascade;GO:0007424//open tracheal system development;GO:0007320//insemination;GO:0010468//regulation of gene expression;GO:0001736//establishment of planar polarity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010669//epithelial structure maintenance;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0035028 19836106 644.00 0.13 0.375 1.52837897235479 Up 0.175406155065381 35486 3560.96 90.875 82.295 -0.143078679592314 Down 0.324230616827368 sxc super sex combs, isoform C K09667|1|0.0|2129|dme:Dmel_CG10392|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part;GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part;GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part GO:0016407//acetyltransferase activity;GO:0005529;GO:0008375//acetylglucosaminyltransferase activity;GO:0016407//acetyltransferase activity;GO:0005529;GO:0008375//acetylglucosaminyltransferase activity;GO:0016407//acetyltransferase activity;GO:0005529;GO:0008375//acetylglucosaminyltransferase activity GO:0051260//protein homooligomerization;GO:0007444//imaginal disc development;GO:0006486//protein glycosylation;GO:0051260//protein homooligomerization;GO:0007444//imaginal disc development;GO:0006486//protein glycosylation;GO:0051260//protein homooligomerization;GO:0007444//imaginal disc development;GO:0006486//protein glycosylation 42550 4255.35 19.835 20.315 0.0344969670858071 Up 0.0960903447364945 E2f E2F transcription factor, isoform F K06620|1|3e-36|154|xla:398159|E2F transcription factor 1/3 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0006277//DNA amplification;GO:0009888//tissue development;GO:0006261//DNA-dependent DNA replication;GO:0048812//neuron projection morphogenesis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0048513//organ development;GO:0006350;GO:0000082//G1/S transition of mitotic cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0006277//DNA amplification;GO:0009888//tissue development;GO:0006261//DNA-dependent DNA replication;GO:0048812//neuron projection morphogenesis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0048513//organ development;GO:0006350;GO:0000082//G1/S transition of mitotic cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0006277//DNA amplification;GO:0009888//tissue development;GO:0006261//DNA-dependent DNA replication;GO:0048812//neuron projection morphogenesis;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006959//humoral immune response;GO:0010468//regulation of gene expression;GO:0048513//organ development;GO:0006350;GO:0000082//G1/S transition of mitotic cell cycle;GO:0043065//positive regulation of apoptotic process 34212 1136.56 24.145 22.59 -0.0960401927795713 Down 0.212224276845859 Tsp29Fb tetraspanin 29Fb, isoform C K06497|1|2e-29|130|ame:552721|CD63 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 42704 2150.90 3.325 2.015 -0.722574501860585 Down 0.369931316866992 CG7031 CG7031, isoform C - - - - 5740236 137.00 0.01 0.57 5.83289001416474 Up 0.385946374323075 5740316 714.00 0.67 0.87 0.376854305390956 Up 0.127592127856294 CG34460 CG34460 - - - - 41807 874.00 0.5 0.635 0.344828496997441 Up 0.106392814687624 RpS5b ribosomal protein S5b, isoform B K02989|1|5e-110|397|dsi:Dsim_GD20391|small subunit ribosomal protein S5e - - - 46040 402.52 725.965 744.61 0.0365849963657053 Up 0.139842821291771 cype cyclope, isoform C K02268|1|2e-37|154|dme:Dmel_CG14028|cytochrome c oxidase subunit VIc [EC:1.9.3.1] GO:0044444//cytoplasmic part GO:0015002//heme-copper terminal oxidase activity GO:0022904//respiratory electron transport chain 35726 585.00 4.935 20.935 2.0847949282839 Up 0.743032624488179 CG12825 CG12825 - - - - 32086 1549.00 0.465 0.41 -0.181606806489948 Down 0.0649848104609695 Or10a odorant receptor 10a K08471|1|0.0|797|dme:Dmel_CG17867|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38734 2170.00 9.575 10.16 0.0855560099598465 Up 0.149385814291375 CG8270 CG8270 - - - - 42548 1139.00 0.545 0.87 0.674759171071802 Up 0.176726984546295 CG15498 CG15498 - - GO:0008233//peptidase activity - 36256 570.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG13193 CG13193 - - - - 19836036 1316.00 0.335 0.445 0.409644240508625 Up 0.0980385682208427 47219 594.00 364.38 204.725 -0.831756487151183 Down 0.715757495707304 RpS14b ribosomal protein S14b, isoform B K02955|1|4e-58|223|dya:Dyak_GE15748|small subunit ribosomal protein S14e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 32974 2069.43 41.2 35.615 -0.21015934712089 Down 0.394102496367719 Zw zwischenferment, isoform C K00036|1|0.0|1071|dme:Dmel_CG12529|glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 34015 1390.95 7.88 7.705 -0.032400672941591 Down 0.0722493726059966 CG5160 CG5160, isoform B K07974|1|8e-166|583|dme:Dmel_CG5160|Ras family, other;K07855|2|2e-28|126|tgu:100227884|Ras-like, estrogen-regulated, growth inhibitor GO:0044464//cell part;GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction 31447 1663.00 5.675 6.27 0.143845050623761 Up 0.173358869369964 Sas10 something about silencing 10 ortholog - GO:0043231//intracellular membrane-bounded organelle - - 36589 6298.34 82.095 91.76 0.16057103408718 Up 0.354708757099458 Ih I[[h]] channel, isoform M K08282|1|3e-101|370|dme:Dmel_CG8585|non-specific serine/threonine protein kinase [EC:2.7.11.1];K04954|2|1e-37|159|mdo:100012531|hyperpolarization activated cyclic nucleotide-gated potassium channel 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0016020//membrane;GO:0031224//intrinsic to membrane GO:0005267//potassium channel activity;GO:0005267//potassium channel activity;GO:0005267//potassium channel activity;GO:0005267//potassium channel activity;GO:0005267//potassium channel activity;GO:0005216//ion channel activity;GO:0005267//potassium channel activity GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0006810//transport;GO:0030001//metal ion transport 35785 2036.72 5.565 6.825 0.294447358465256 Up 0.301611411966715 coil coilin, isoform E - - - - 5740119 834.00 0.52 1.8 1.79141337818858 Up 0.421146479989433 31027 3619.00 11.52 11.58 0.00749453654692445 Up 0.0502575617487782 Rbf Retinoblastoma-family protein K04681|1|0.0|1681|dme:Dmel_CG7413|retinoblastoma-like - - - 19835632 3670.00 10.27 6.985 -0.556104160908732 Down 0.494056267335887 38069 718.00 5.975 6.225 0.0591351240873324 Up 0.0939439968300092 Cypl Cyclophilin-like K12733|1|5e-88|323|dme:Dmel_CG13892|peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity GO:0000377;GO:0046662//regulation of oviposition;GO:0044267//cellular protein metabolic process 318874 783.00 0.415 0.415 0 - 0.0382380134724607 Nnf1b Nnf1b - GO:0000776//kinetochore - GO:0000070//mitotic sister chromatid segregation 35856 1103.00 0.56 1.05 0.906890595608518 Up 0.239202218993528 CG8584 CG8584 K01090|1|1e-51|203|dre:492343|protein phosphatase [EC:3.1.3.16] GO:0031224//intrinsic to membrane GO:0042578//phosphoric ester hydrolase activity GO:0006810//transport 34963 1019.00 16.63 14.67 -0.180919297613879 Down 0.299597147008321 CG5869 CG5869 - GO:0044464//cell part GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding GO:0022008//neurogenesis 38640 2177.00 0.32 0.17 -0.912537158749661 Down 0.126238277638357 Sse separase K02365|1|0.0|1272|dme:Dmel_CG10583|separase [EC:3.4.22.49] GO:0043231//intracellular membrane-bounded organelle GO:0016787//hydrolase activity GO:0006909//phagocytosis;GO:0019538//protein metabolic process;GO:0000819//sister chromatid segregation;GO:0007126//meiosis 19834826 697.00 0.115 0.07 -0.716207033999408 Down 0.0690133403777572 48341 808.00 0.84 0.725 -0.212408332763826 Down 0.0889578655395588 GstD8 glutathione S transferase D8 K00432|1|1e-122|438|dme:Dmel_CG4421|glutathione peroxidase [EC:1.11.1.9];K00799|2|1e-115|415|der:Dere_GG18806|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity - 14462527 302.00 5.795 4.645 -0.319130064623819 Down 0.298144234579316 38513 2173.83 61.815 29.42 -1.07115971774683 Down 0.719191652357681 ImpL2 Ecdysone-inducible gene L2, isoform D K06757|1|4e-10|65.5|oaa:100075960|neurofascin;K06758|2|9e-10|64.3|tgu:100220455|L1 cell adhesion molecule like protein - - - 19836079 549.00 0.08 0.205 1.35755200461808 Up 0.120294544974244 318595 952.00 4.58 3.845 -0.252364000135117 Down 0.22265882974508 CG31111 CG31111 K09188|1|9e-09|60.8|bfo:BRAFLDRAFT_125138|myeloid/lymphoid or mixed-lineage leukemia protein 3;K09187|2|1e-08|60.5|rno:100362634|myeloid/lymphoid or mixed-lineage leukemia protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0009987//cellular process 44817 4387.76 42.04 33.56 -0.325019953522355 Down 0.511425175009906 for foraging, isoform K K07376|1|0.0|1569|dme:Dmel_CG10033|protein kinase, cGMP-dependent [EC:2.7.11.12] GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0016020//membrane GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559 GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process;GO:0007613//memory;GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0007626//locomotory behavior;GO:0030537//larval behavior;GO:0046958//nonassociative learning;GO:0044057;GO:0006464//cellular protein modification process 39997 1485.00 9.71 9.43 -0.0422135247440959 Down 0.0909391097609299 CG14353 CG14353 - - - - 3772625 540.00 0.08 0.01 -3 Down 0.110718531237617 CG33795 CG33795 K12602|1|8e-25|112|dpo:Dpse_GA17766|WD repeat-containing protein 61;K09255|2|2e-10|65.1|dpe:Dper_GL18753|Rel/ankyrin family, other - - - 42142 1613.00 4.83 5.18 0.100928908850781 Up 0.123398494254392 CG17806 CG17806 K09228|1|4e-27|122|hsa:374900|KRAB domain-containing zinc finger protein - - - 41225 10020.59 31.09 30.68 -0.0191521338381307 Down 0.0807026812838463 Mical molecule interacting with CasL, isoform M K05699|1|6e-08|60.1|dse:Dsec_GM18928|actinin alpha GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0033267//axon part;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis;GO:0031032//actomyosin structure organization;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0048812//neuron projection morphogenesis 32545 1377.45 943.01 870.05 -0.116174757725282 Down 0.305210672302206 Gapdh2 glyceraldehyde 3 phosphate dehydrogenase 2, isoform C K00134|1|2e-179|629|dya:Dyak_GE17231|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008943;GO:0000166//nucleotide binding GO:0006007//glucose catabolic process 41543 2244.00 11.12 11.235 0.0148433364563996 Up 0.0555739004094571 CG5608 CG5608 - - - - 41583 1728.39 19.25 21.22 0.140566210445139 Up 0.268260467573636 beat-Vb beat-Vb, isoform B - - - - 19835559 778.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 31955 5399.78 60.64 81.45 0.425644945241788 Up 0.595264826310923 Hk hyperkinetic, isoform M K04883|1|1e-82|308|cfa:489626|potassium voltage-gated channel Shaker-related subfamily A, beta member 2;K04882|5|1e-81|305|gga:395730|potassium voltage-gated channel Shaker-related subfamily A, beta member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral to plasma membrane GO:0015631//tubulin binding;GO:0003824//catalytic activity;GO:0005267//potassium channel activity;GO:0015631//tubulin binding;GO:0003824//catalytic activity;GO:0005267//potassium channel activity GO:0006909//phagocytosis;GO:0042051//compound eye photoreceptor development;GO:0007010//cytoskeleton organization;GO:0010259//multicellular organismal aging;GO:0022410;GO:0046907//intracellular transport;GO:0008152//metabolic process;GO:0030001//metal ion transport;GO:0006909//phagocytosis;GO:0042051//compound eye photoreceptor development;GO:0007010//cytoskeleton organization;GO:0010259//multicellular organismal aging;GO:0022410;GO:0046907//intracellular transport;GO:0008152//metabolic process;GO:0030001//metal ion transport 39319 2537.90 48.28 46.575 -0.0518699069260214 Down 0.146678113855501 CG11658 CG11658, isoform E K10305|1|0.0|692|dya:Dyak_GE20186|F-box protein 25/32 - - - 14462767 853.00 1.42 1.675 0.238270165840453 Up 0.128945978074231 19834874 1201.00 0.76 1.28 0.752072486556414 Up 0.237617223616431 34370 1549.54 61.985 60.315 -0.0394022972880017 Down 0.129771496499802 Rsf1 repressor splicing factor 1, isoform B K12896|1|9e-15|81.3|ptr:459167|splicing factor, arginine/serine-rich 7 GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0033119//negative regulation of RNA splicing 46080 792.00 87.785 74.895 -0.229105037219084 Down 0.443402456742835 Sec61beta Sec61 beta subunit K09481|1|2e-25|116|dya:Dyak_GE13599|protein transport protein SEC61 subunit beta GO:0071256 GO:0022892 GO:0007033//vacuole organization;GO:0006914//autophagy 36896 3406.00 21.825 27.42 0.329246917262423 Up 0.484678378021397 CG8910 CG8910 - - - - 39777 603.67 41.98 40.445 -0.0537408056575796 Down 0.14515915995245 MED10 mediator complex subunit 10, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 40792 3112.24 54.36 46.35 -0.229976117254498 Down 0.427915731079118 CG1021 dementin, isoform H - - - - 3885606 1227.00 0.945 0.885 -0.0946368741380754 Down 0.0601637828556333 CG34043 CG34043 - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43311 1273.00 11.645 11.115 -0.067202691183876 Down 0.131686699247127 CG5646 CG5646 K03454|1|1e-32|140|cel:C54G10.4|mitochondrial carrier protein, MC family GO:0031224//intrinsic to membrane;GO:0031967 - GO:0006810//transport 34969 2125.49 107.295 84.34 -0.347293920629638 Down 0.558413683793422 cact cactus, isoform E K09259|1|0.0|783|dme:Dmel_CG5848|ankyrin only family, other GO:0044424//intracellular part;GO:0045202//synapse;GO:0044424//intracellular part;GO:0045202//synapse;GO:0044424//intracellular part;GO:0045202//synapse;GO:0044424//intracellular part;GO:0045202//synapse GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0007166//cell surface receptor signaling pathway;GO:0006909//phagocytosis;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0003006//developmental process involved in reproduction;GO:0048534;GO:0002783;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0006909//phagocytosis;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0003006//developmental process involved in reproduction;GO:0048534;GO:0002783;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0006909//phagocytosis;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0003006//developmental process involved in reproduction;GO:0048534;GO:0002783;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0006909//phagocytosis;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0003006//developmental process involved in reproduction;GO:0048534;GO:0002783;GO:0009798//axis specification;GO:0007292//female gamete generation;GO:0033554//cellular response to stress 33286 3266.00 0.05 0.23 2.20163386116965 Up 0.157872143706248 CG14339 CG14339 - - - - 43565 4427.13 13.605 14.5 0.0919159436526181 Up 0.172830537577599 Axn axin, isoform G K02157|1|0.0|1145|dme:Dmel_CG7926|axin 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding;GO:0060089;GO:0019900//kinase binding;GO:0060089;GO:0019900//kinase binding;GO:0060089;GO:0019900//kinase binding;GO:0060089;GO:0019900//kinase binding;GO:0060089 GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0007292//female gamete generation;GO:0019827//stem cell maintenance;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0007292//female gamete generation;GO:0019827//stem cell maintenance;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0007292//female gamete generation;GO:0019827//stem cell maintenance;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0007292//female gamete generation;GO:0019827//stem cell maintenance;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0007292//female gamete generation;GO:0019827//stem cell maintenance 45326 2307.72 113.87 79.43 -0.5196317986701 Down 0.639116365077269 Lsp2 larval serum protein 2, isoform B K00505|1|6e-52|206|dya:Dyak_GE14257|tyrosinase [EC:1.14.18.1] GO:0044444//cytoplasmic part GO:0022892 GO:0051234//establishment of localization 42612 741.00 0.215 0.955 2.15116407333365 Up 0.336844538370096 CG5388 CG5388, isoform B - - - - 37749 5461.00 7.675 9.105 0.246492266719297 Up 0.300686831330075 CG30183 CG30183, isoform C - - - - 318649 1988.00 0.075 0.025 -1.58496250072116 Down 0.081858407079646 CG31262 CG31262, isoform F K03307|1|3e-104|347|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport 34110 1846.00 9.07 10.18 0.166563105547173 Up 0.242042002377493 Rbsn-5 Rabenosyn-5 K12481|1|0.0|922|dme:Dmel_CG8506|rabenosyn-5 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0006906//vesicle fusion;GO:0019094//pole plasm mRNA localization;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0007017//microtubule-based process 31697 482.20 135.37 145.92 0.10826958290114 Up 0.277605336151103 CG18624 CG18624, isoform E K03957|1|1e-26|119|dme:Dmel_CG18624|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 1 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016651//oxidoreductase activity, acting on NAD(P)H - 41436 2492.00 1.815 1.965 0.114559764262856 Up 0.0853586052040682 CG6962 CG6962 K12353|1|0.0|1450|dme:Dmel_CG6962|sphingomyelin phosphodiesterase 4 [EC:3.1.4.12] - - - 19835274 322.00 0.01 0.16 4 Up 0.178939373926826 19835859 549.00 3.68 4.22 0.197537232650173 Up 0.182076343943997 31842 4720.37 20.875 25.305 0.277646276759945 Up 0.434784044379871 AP-1gamma adaptor protein complex 1, gamma subunit, isoform I K12391|1|0.0|1624|dme:Dmel_CG9113|AP-1 complex subunit gamma-1 GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892 GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport 37968 1656.99 61.74 44.76 -0.463995446638731 Down 0.600746268656716 Reg-5 rhythmically expressed gene 5, isoform B - - - - 42679 2670.34 7.2 7.63 0.0836861505048558 Up 0.12696473385286 wfs1 wolfram syndrome 1, isoform C K14020|1|0.0|1660|dme:Dmel_CG4917|wolfamin - - - 43615 853.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 Osi23 osiris 23 - - - - 36848 3291.63 29.26 33.845 0.210012947395958 Up 0.38356888125743 Syn2 Syntrophin-like 2, isoform E K05631|1|2e-10|68.9|cin:100186585|atrophin-1 interacting protein 3 (BAI1-associated protein 1);K06092|2|2e-09|65.1|ecb:100070486|InaD-like protein;K06095|4|4e-09|64.3|bta:536863|multiple PDZ domain protein - - - 31256 1357.00 28.635 29.52 0.0439131179353022 Up 0.120228503500198 eIF2B-beta eIF2B-beta K03754|1|0.0|692|dme:Dmel_CG2677|translation initiation factor eIF-2B beta subunit - - - 34061 1097.60 1.88 2.26 0.26559011073755 Up 0.163188482366926 CG7164 CG7164, isoform B - - - - 246589 2830.23 3.73 4.095 0.134687821385771 Up 0.135318980319641 CG30395 CG30395, isoform E K14007|1|1e-12|75.5|api:100163637|protein transport protein SEC24;K06672|2|8e-11|69.7|xla:445865|cohesin loading factor subunit SCC2;K11657|3|2e-09|65.5|dre:327618|remodeling and spacing factor 1;K11321|5|4e-08|60.8|cin:100175561|bromodomain-containing protein 8 - - - 45248 8809.77 86.035 97.67 0.182991813011198 Up 0.384889710738344 Nckx30C Nckx30C, isoform F K13750|1|0.0|1272|dme:Dmel_CG18660|solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0005515//protein binding;GO:0015368//calcium:cation antiporter activity GO:0070838//divalent metal ion transport;GO:0001654//eye development;GO:0070838//divalent metal ion transport;GO:0001654//eye development;GO:0070838//divalent metal ion transport;GO:0001654//eye development;GO:0001654//eye development;GO:0007611//learning or memory;GO:0048167//regulation of synaptic plasticity;GO:0006816//calcium ion transport 2768954 821.14 50.65 51.005 0.0100764118150891 Up 0.0651499141460837 CG12355 CG12355, isoform E K13349|1|7e-70|263|dme:Dmel_CG12355|Mpv17-like protein GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 3772415 829.21 62.475 64.56 0.0473615823037145 Up 0.149848104609695 37307 695.00 4.16 3.635 -0.194628164221498 Down 0.176693963809272 CG16739 CG16739 - - - - 39013 4327.76 41.705 36.65 -0.186407159957769 Down 0.370657773081495 dally division abnormally delayed, isoform B K02306|1|0.0|1138|dme:Dmel_CG4974|dally GO:0031224//intrinsic to membrane;GO:0019898//extrinsic to membrane;GO:0031012//extracellular matrix GO:0043394//proteoglycan binding GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007127//meiosis I;GO:0048812//neuron projection morphogenesis;GO:0042078//germ-line stem cell division;GO:0007478//leg disc morphogenesis;GO:0019827//stem cell maintenance;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0001654//eye development;GO:0035264//multicellular organism growth;GO:0030509//BMP signaling pathway;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis 38352 6455.57 43.17 54.985 0.349009009890346 Up 0.537445515783912 Shab shaker cognate b, isoform N K04886|1|0.0|637|bta:535990|potassium voltage-gated channel Shab-related subfamily B member 2;K04885|4|6e-180|632|cfa:485918|potassium voltage-gated channel Shab-related subfamily B member 1 GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport;GO:0050804//regulation of synaptic transmission;GO:0007626//locomotory behavior;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport 30983 1097.00 0.045 0.01 -2.16992500144231 Down 0.0694426099590543 l(1)sc lethal of scute K09067|1|2e-73|276|dme:Dmel_CG3839|achaete-scute complex protein - - - 32394 826.13 17.12 21.225 0.310081852039254 Up 0.447695152555805 CG14414 CG14414, isoform E - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 14462864 518.00 0.58 0.18 -1.68805599368526 Down 0.238607845727117 19835581 1120.00 0.075 0.235 1.64769825606912 Up 0.143376040153216 39335 1067.00 6.435 7.795 0.276608874477083 Up 0.3072249372606 CG14130 CG14130 K10769|1|1e-138|492|dme:Dmel_CG14130|alkylated DNA repair protein alkB homolog 7 - - - 42973 2200.18 165.43 124.43 -0.410886524275134 Down 0.599524501386871 CG11089 CG11089, isoform B K00602|1|0.0|1159|dme:Dmel_CG11089|phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] - GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0019238//cyclohydrolase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0019238//cyclohydrolase activity GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process 32464 4251.00 3.74 4.745 0.343369817133473 Up 0.282822612600713 CG6227 CG6227 K12811|1|0.0|1385|dme:Dmel_CG6227|ATP-dependent RNA helicase DDX46/PRP5 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0000380//alternative mRNA splicing, via spliceosome 318906 363.62 35.125 22.36 -0.651578037152461 Down 0.632974507991018 CG31704 CG31704, isoform B - - GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity GO:0019538//protein metabolic process 36595 2371.00 20.785 40.42 0.959526573755363 Up 0.692246730947035 Arc1 Activity-regulated cytoskeleton associated protein 1 - - GO:0005488//binding GO:0042594//response to starvation 33883 2535.07 150.71 116.025 -0.377339449167284 Down 0.583047153612469 Cpr cytochrome P450 reductase, isoform D K00327|1|0.0|1038|dme:Dmel_CG11567|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0000166//nucleotide binding;GO:0046914//transition metal ion binding;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0000166//nucleotide binding GO:0008152//metabolic process;GO:0008152//metabolic process 40249 3147.39 31.365 30.455 -0.0424764582270595 Down 0.120855897503632 RhoBTB Rho-related BTB domain containing, isoform C K07868|1|0.0|1380|dme:Dmel_CG5701|Rho-related BTB domain-containing protein 1/2 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 44660 2852.00 1.13 2.1 0.894066555250935 Up 0.333047153612469 xmas-1 xmas-1 - - - - 3885636 822.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 CG34030 CG34030 - - - - 37628 542.00 1023.97 967.92 -0.0812137315722666 Down 0.226324131554616 RpL23 ribosomal protein L23 K02894|1|1e-75|281|dvi:Dvir_GJ22396|large subunit ribosomal protein L23e GO:0015934//large ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 41360 1817.00 168.08 187.615 0.15862711019933 Up 0.364747061154405 CG5214 CG5214 K00658|1|9e-132|470|dme:Dmel_CG5214|2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0016751 GO:0009060//aerobic respiration 33743 2152.93 71.205 83.35 0.227203648723191 Up 0.441949544313829 CG4230 CG4230, isoform C - - - - 19835465 435.00 0.555 0.325 -0.772048053321651 Down 0.152654867256637 33786 955.00 0.695 1.105 0.668961486667924 Up 0.202318055739004 CG14013 CG14013 - GO:0031224//intrinsic to membrane - - 38094 1251.00 12.41 13.215 0.0906733095112132 Up 0.167481178179897 CG42553 CG42553 - - - - 19835056 500.00 0.27 0.25 -0.111031312388744 Down 0.0478470479461102 246485 922.95 41.485 43.785 0.0778469254024074 Up 0.199445251618016 CG30152 CG30152, isoform D - - - - 35188 1773.33 10.72 7.895 -0.441293734597535 Down 0.449643376040153 amd alpha methyl dopa-resistant, isoform B K01618|1|0.0|902|dme:Dmel_CG10501| [EC:4.1.1.-];K01593|3|2e-132|473|api:100160466|aromatic-L-amino-acid decarboxylase [EC:4.1.1.28] - GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0005198//structural molecule activity;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0005198//structural molecule activity GO:0006584//catecholamine metabolic process;GO:0043436;GO:0042335//cuticle development;GO:0006584//catecholamine metabolic process;GO:0043436;GO:0042335//cuticle development 40290 1104.72 14.67 15.13 0.0445431165433473 Up 0.105831462158235 CG4074 CG4074, isoform B - GO:0012505//endomembrane system - GO:0046907//intracellular transport 41675 5000.63 32.375 35.605 0.137199659872471 Up 0.295502575617488 flfl falafel, isoform E - - - - 37031 2073.00 0.06 0.19 1.66296501272243 Up 0.128285563333774 CG18635 CG18635 - - - - 36857 2211.00 76.685 46.415 -0.724353287919673 Down 0.679434684982169 CG8306 CG8306 K13356|1|2e-102|373|phu:Phum_PHUM423990|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 35196 414.73 9.825 6.685 -0.555529847052616 Down 0.488640866464139 l(2)37Cg lethal (2) 37Cg, isoform D K03020|1|2e-56|216|dsi:Dsim_GD21773|DNA-directed RNA polymerase III subunit C19 [EC:2.7.7.6] GO:0044452;GO:0015630//microtubule cytoskeleton GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 2768967 743.00 0.705 0.075 -3.23266075679027 Down 0.335589750363228 CG13028 CG13028 - - - - 36676 1309.58 5.74 6.57 0.194842633646642 Up 0.221371021001189 CG10265 CG10265, isoform C - GO:0016020//membrane - - 34739 3020.00 8.705 10.715 0.299715647025447 Up 0.365143309998679 CG16825 CG16825, isoform B - - - - 31094 1713.00 1.44 2.225 0.627736524411447 Up 0.280775326905297 CG14785 CG14785 - - - - 19835279 494.00 0.255 0.01 -4.6724253419715 Down 0.24085325584467 14462531 366.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 35834 432.00 0.69 0.115 -2.58496250072116 Down 0.309569409589222 CG12780 CG12780 - - - - 41163 3811.52 24.95 21.59 -0.208676572202118 Down 0.364185708625017 CG8312 CG8312, isoform D - - - - 44573 2027.86 46.405 42.65 -0.121734518261336 Down 0.273940034341566 MAPk-Ak2 MAP kinase activated protein-kinase-2, isoform F K04443|1|0.0|739|dme:Dmel_CG3086|mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] - GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0065008;GO:0006464//cellular protein modification process;GO:0065008;GO:0006464//cellular protein modification process;GO:0065008;GO:0006464//cellular protein modification process 39972 2778.00 19.4 22.35 0.20421817899619 Up 0.347906485272751 Ccn Ccn K06827|1|6e-24|113|cfa:476202|connective tissue growth factor - - - 38594 2273.00 0.225 0.725 1.68805599368526 Up 0.268161405362568 Gen XPG-like endonuclease K10846|1|1e-23|112|tad:TRIADDRAFT_23638|DNA excision repair protein ERCC-5;K04799|3|4e-21|103|dwi:Dwil_GK21315|flap endonuclease-1 [EC:3.-.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003677//DNA binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0004520//endodeoxyribonuclease activity GO:0006308//DNA catabolic process;GO:0006281//DNA repair 42166 600.00 23.085 24.17 0.0662617407162162 Up 0.163320565315018 Cbp20 cap binding protein 20 K12883|1|4e-87|320|dsi:Dsim_GD19204|nuclear cap-binding protein subunit 2 - - - 50092 686.00 0.415 0.145 -1.51705843621935 Down 0.188152159556201 CheB98a chemosensory protein A 98a - - - GO:0009593//detection of chemical stimulus 5740446 3091.27 10.88 14.155 0.379633192655408 Up 0.453275657112667 Rgk3 Rad, Gem/Kir family member 3, isoform F K07847|1|2e-39|164|phu:Phum_PHUM550210|Rad and Gem related GTP binding protein 1 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 42775 1749.00 0.025 0.055 1.13750352374993 Up 0.0654471007792894 CG16732 CG16732, isoform B K00699|1|2e-117|423|dpo:Dpse_GA18421|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups - 36195 616.18 19.52 9.09 -1.10260085336878 Down 0.671377625148593 TpnC47D troponin C at 47D, isoform B K02183|1|6e-24|110|ptr:738819|calmodulin - GO:0046872//metal ion binding - 35900 4781.84 19.89 21.56 0.116313901918761 Up 0.237055871087043 babo baboon, isoform C K13569|1|0.0|1228|dme:Dmel_CG8224|TGF-beta receptor, invertebrate GO:0016020//membrane;GO:0043235//receptor complex;GO:0016020//membrane;GO:0043235//receptor complex;GO:0016020//membrane;GO:0043235//receptor complex GO:0032559;GO:0032403//protein complex binding;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0032559;GO:0032403//protein complex binding;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0032559;GO:0032403//protein complex binding;GO:0005025//transforming growth factor beta receptor activity, type I GO:0000278//mitotic cell cycle;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0009416//response to light stimulus;GO:0035264//multicellular organism growth;GO:0007472//wing disc morphogenesis;GO:0000278//mitotic cell cycle;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0009416//response to light stimulus;GO:0035264//multicellular organism growth;GO:0007472//wing disc morphogenesis;GO:0000278//mitotic cell cycle;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048812//neuron projection morphogenesis;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0009416//response to light stimulus;GO:0035264//multicellular organism growth;GO:0007472//wing disc morphogenesis 49424 2358.00 82.26 52.95 -0.635560387620683 Down 0.663617751948223 l(2)35Bg CIAPIN1 ortholog - GO:0044424//intracellular part - GO:0012501//programmed cell death 19835946 271.00 0.17 0.01 -4.08746284125034 Down 0.187062475234447 40347 2043.00 3.2 5.29 0.725195817226663 Up 0.447265882974508 CG9389 CG9389 K01092|1|0.0|988|dme:Dmel_CG9389|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] - GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process 33804 1805.00 0.975 1.64 0.750221690868473 Up 0.268458591995773 CG11029 CG11029 K06269|1|1e-25|117|tgu:100232535|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 33850 2219.55 12.635 10.05 -0.330230162878484 Down 0.408169330339453 CG9135 CG9135, isoform D K10615|1|2e-27|124|dya:Dyak_GE21143|E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - - 3346192 5667.17 101.875 109.125 0.0991815945110002 Up 0.253929467705719 Vmat vesicular monoamine transporter, isoform F K08155|1|0.0|919|dme:Dmel_CG33528|MFS transporter, DHA1 family, solute carrier family 18 (vesicular monoamine) GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0031224//intrinsic to membrane;GO:0045202//synapse GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0051937;GO:0051937;GO:0051937 36477 1011.00 2.03 0.94 -1.11074706550754 Down 0.365440496631885 CG4734 CG4734 - - - - 40575 3606.93 24.025 25.015 0.0582570213315901 Up 0.149484876502444 5-HT2 5-hydroxytryptamine (serotonin) receptor 2A, isoform H K04159|1|1e-38|162|cfa:450240|5-hydroxytryptamine (serotonin) receptor 2C GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004993//serotonin receptor activity;GO:0004993//serotonin receptor activity;GO:0004993//serotonin receptor activity;GO:0004993//serotonin receptor activity;GO:0004993//serotonin receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0010004//gastrulation involving germ band extension;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010004//gastrulation involving germ band extension;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010004//gastrulation involving germ band extension;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010004//gastrulation involving germ band extension;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010004//gastrulation involving germ band extension 318274 829.00 0.285 0.635 1.15579467260742 Up 0.208724078721437 CG32988 CG32988 - - - - 43638 1496.00 1.01 1.215 0.266601020853986 Up 0.116959450534936 CG31021 CG31021 K00472|1|9e-45|181|dvi:Dvir_GJ22993|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 31213 1921.00 10.26 10.2 -0.00846157874819618 Down 0.0502575617487782 CG3071 CG3071 K12602|1|2e-14|81.3|xla:444484|WD repeat-containing protein 61 - - - 33238 968.99 0.855 1.395 0.70626879694329 Up 0.237881389512614 Ptth prothoracicotropic hormone, isoform F - - - - 34197 765.00 21.85 18.925 -0.207339979514867 Down 0.354213446044116 Trs23 TRAPP subunit 23 ortholog - GO:0044431//Golgi apparatus part - GO:0048193//Golgi vesicle transport 39715 2199.00 1.91 0.83 -1.20238939668882 Down 0.367652886012416 pgant8 polypeptide GalNAc transferase 8 K00710|1|0.0|1192|dme:Dmel_CG7297|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process 38535 576.09 18.3 18.295 -0.000394232832317513 Down 0.0382380134724607 mRpS6 mitochondrial ribosomal protein S6, isoform B K03307|1|2e-13|75.5|ptr:473978|solute:Na+ symporter, SSS family GO:0000314//organellar small ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression 40220 4030.44 12.985 12.775 -0.0235227228534236 Down 0.0702351076476027 CG17233 CG17233, isoform I - - - - 14462687 318.00 0.01 0.315 4.97727992349992 Up 0.276482631092326 CG43703 CG43703 - - - - 36410 1464.00 30.69 77.11 1.32914932218144 Up 0.745079910183595 CG12374 CG12374 K01290|1|1e-77|290|dan:Dana_GF14014|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 3772703 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 37332 2819.81 2.57 2.385 -0.107779093188367 Down 0.0951327433628319 Rcd6 reduction in Cnn dots 6, isoform B - - - - 41290 1118.00 12.105 10.685 -0.180016171339126 Down 0.270571919165236 TfIIFbeta transcription factor TFIIFbeta K03139|1|1e-136|486|dme:Dmel_CG6538|transcription initiation factor TFIIF beta subunit GO:0005667//transcription factor complex GO:0003678//DNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, nucleic acid binding;GO:0032559;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 19836166 3053.52 10.25 12.4 0.274716210881429 Up 0.358142913749835 - CG45083, isoform B - - - - 35733 1840.12 46.035 53.54 0.217885992453137 Up 0.416325452384097 CG1882 CG1882, isoform G K13698|1|1e-98|360|xtr:550041|abhydrolase domain-containing protein 4 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - 42715 2091.30 9.475 3.53 -1.42445775978727 Down 0.642847708360851 CG34375 CG34375, isoform C K08742|1|1e-10|68.9|xtr:100124319|E3 ubiquitin-protein ligase SIAH2 [EC:6.3.2.19];K04506|3|7e-10|66.2|hmg:100204840|E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0019941//modification-dependent protein catabolic process;GO:0032501//multicellular organismal process;GO:0019941//modification-dependent protein catabolic process;GO:0032501//multicellular organismal process 39368 5519.96 10.065 6.465 -0.638624897111085 Down 0.517467969885088 rols rolling pebbles, isoform I K12460|1|2e-31|139|mdo:100032130|ankyrin repeat-rich membrane spanning protein;K10380|3|3e-30|135|ecb:100055459|ankyrin GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0000768//syncytium formation by plasma membrane fusion;GO:0000768//syncytium formation by plasma membrane fusion;GO:0000768//syncytium formation by plasma membrane fusion;GO:0000768//syncytium formation by plasma membrane fusion;GO:0000768//syncytium formation by plasma membrane fusion 19835217 472.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 318060 1006.00 0.115 0.05 -1.20163386116965 Down 0.0859859992075023 CG32507 CG32507 K11308|1|3e-06|51.2|dwi:Dwil_GK16378|histone acetyltransferase MYST1 [EC:2.3.1.48] - - - 31557 11139.00 27.71 34.87 0.331579653295287 Up 0.502047285695417 Rbcn-3A Rabconnectin-3A K03130|1|9e-11|71.6|cin:100184951|transcription initiation factor TFIID subunit D4;K07825|2|3e-09|66.6|bta:513340|guanine nucleotide binding protein (G protein), beta 3 - - - 36384 1789.16 838.14 752.005 -0.156448992573274 Down 0.373563597939506 Galpha49B G protein alpha q subunit, isoform K K04634|1|0.0|674|dya:Dyak_GE12481|guanine nucleotide binding protein (G protein), alpha q polypeptide GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus 36016 1379.03 8.25 4.235 -0.96203214980098 Down 0.565678245938449 CG1667 CG1667, isoform C K12654|1|3e-09|63.5|xtr:100127621|transmembrane protein 173 GO:0044464//cell part - - 19834999 446.00 0.675 1.845 1.45066140900957 Up 0.392946770571919 12797940 438.00 2.29 6.18 1.43225923980743 Up 0.591599524501387 19834809 528.00 7.43 6.305 -0.236865840210376 Down 0.268788799366002 43811 3111.38 43.645 36.9 -0.242195570939516 Down 0.429434684982169 myo myoglianin, isoform D K04669|1|0.0|1134|dme:Dmel_CG1838|TGF-beta receptor, other - - - 37552 4649.09 43.975 50.645 0.203736266230005 Up 0.392220314357416 Liprin-gamma Liprin-gamma, isoform E - - - - 34433 1277.00 52.045 54.13 0.0566688186046192 Up 0.167481178179897 CHIP CHIP K09561|1|9e-168|589|dme:Dmel_CG5203|STIP1 homology and U-box containing protein 1 [EC:6.3.2.19] GO:0043234//protein complex;GO:0031674//I band GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation 14462408 543.00 3.66 4.675 0.353122716490956 Up 0.285629375247656 34552 1445.00 33.345 21.58 -0.627775584260129 Down 0.625511821423854 hgo homogentisate 1,2-dioxygenase K00451|1|0.0|928|dme:Dmel_CG4779|homogentisate 1,2-dioxygenase [EC:1.13.11.5] - GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process 35063 3362.00 0.2 0.285 0.51096191927738 Up 0.0930524369303923 CG15144 CG15144 - - - - 318007 750.24 1.035 1.225 0.243150981503246 Up 0.111114780081891 CG32391 CG32391, isoform B - - - - 43148 5847.00 10.8 12.46 0.206272755973171 Up 0.30038964469687 CG42261 CG42261 K10770|1|3e-24|114|xtr:550051|alkylated DNA repair protein alkB homolog 8;K1456|5|2e-22|108|dre:556362|protein-like - - - 43538 472.00 26.75 19.515 -0.45495542873692 Down 0.552635054814423 CG15515 CG15515 - - - - 12798259 682.00 0.065 0.135 1.05444778402238 Up 0.0917316074494783 33718 769.00 14.94 16.52 0.145033538630208 Up 0.260335490688152 CG8891 CG8891 K01519|1|1e-109|395|dse:Dsec_GM18051|nucleoside-triphosphate pyrophosphatase [EC:3.6.1.19] - GO:0003824//catalytic activity - 37122 775.54 33.555 32.265 -0.0565577316360578 Down 0.157640998547088 CG5189 CG5189, isoform B K10599|1|2e-20|101|dya:Dyak_GE13910|pre-mRNA-processing factor 19 [EC:6.3.2.19] - - - 42924 1021.00 2.09 8.475 2.01971042594282 Up 0.675868445383701 CG13618 CG13618 - - - - 31725 2301.00 0.36 0.67 0.89616418901546 Up 0.186930392286356 CG1571 CG1571 K11143|1|2e-86|320|tca:660389|dynein intermediate chain 2, axonemal - - - 42444 2907.00 17.005 19.52 0.198994046855045 Up 0.335259542993 CG5466 CG5466 - - - - 36699 1387.02 69.895 66.275 -0.0767244897469553 Down 0.208724078721437 Arf51F ADP ribosylation factor at 51F, isoform E K07941|1|2e-98|359|dya:Dyak_GE13644|ADP-ribosylation factor 6 GO:0005626//insoluble fraction;GO:0031252//cell leading edge;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0005626//insoluble fraction;GO:0031252//cell leading edge;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0005626//insoluble fraction;GO:0031252//cell leading edge;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0005626//insoluble fraction;GO:0031252//cell leading edge;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0005626//insoluble fraction;GO:0031252//cell leading edge;GO:0031090//organelle membrane;GO:0005768//endosome GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding GO:0012501//programmed cell death;GO:0045806//negative regulation of endocytosis;GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0048513//organ development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0016601//Rac protein signal transduction;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0033206//cytokinesis after meiosis;GO:0001505//regulation of neurotransmitter levels;GO:0012501//programmed cell death;GO:0045806//negative regulation of endocytosis;GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0048513//organ development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0016601//Rac protein signal transduction;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0033206//cytokinesis after meiosis;GO:0001505//regulation of neurotransmitter levels;GO:0012501//programmed cell death;GO:0045806//negative regulation of endocytosis;GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0048513//organ development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0016601//Rac protein signal transduction;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0033206//cytokinesis after meiosis;GO:0001505//regulation of neurotransmitter levels;GO:0012501//programmed cell death;GO:0045806//negative regulation of endocytosis;GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0048513//organ development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0016601//Rac protein signal transduction;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0033206//cytokinesis after meiosis;GO:0001505//regulation of neurotransmitter levels;GO:0012501//programmed cell death;GO:0045806//negative regulation of endocytosis;GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0048513//organ development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0016601//Rac protein signal transduction;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0033206//cytokinesis after meiosis;GO:0001505//regulation of neurotransmitter levels 8674061 421.00 0.825 0.74 -0.156868848616866 Down 0.0746268656716418 34624 2089.00 24.03 19.98 -0.266280065337448 Down 0.420287940826839 JhI-21 JhI-21, isoform E K13780|1|5e-130|465|dre:797250|solute carrier family 7 (L-type amino acid transporter), member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity GO:0015801//aromatic amino acid transport;GO:0015820//leucine transport;GO:0015801//aromatic amino acid transport;GO:0015820//leucine transport 37608 691.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 Obp58c Odorant-binding protein 58c - - GO:0005488//binding GO:0051234//establishment of localization 12797917 324.00 0.275 0.615 1.16115479181458 Up 0.205587108704266 CG43249 CG43249 - - - - 31942 5593.95 16.25 18.425 0.181224901179253 Up 0.308215559371285 ZAP3 ZAP3, isoform F - - - - 31638 2189.00 8.25 7.91 -0.0607164246603862 Down 0.106987187954035 CG32732 CG32732 K05302|1|1e-07|58.9|mcc:707353|SET domain-containing protein 6 - - - 19836240 2110.00 5.945 6.3 0.0836750186416231 Up 0.117983093382644 - pre-mod(mdg4)-AB - - - - 14462732 631.00 0.14 0.155 0.146841388329271 Up 0.0503566239598468 33849 1389.13 23.475 24.11 0.038506493061389 Up 0.113690397569674 CG12393 CG12393, isoform D K12326|1|9e-11|68.6|aga:AgaP_AGAP001238|Ras-specific guanine nucleotide-releasing factor 2;K01109|2|1e-10|68.2|nvi:100116145|inositol polyphosphate-4-phosphatase [EC:3.1.3.66];K04349|5|7e-09|62.4|tca:658869|Ras-specific guanine nucleotide-releasing factor 1 - - - 35706 1105.00 1.04 0.235 -2.14585086646345 Down 0.349062211068551 CG2070 CG2070, isoform B K00100|1|0.0|633|dme:Dmel_CG2070| [EC:1.1.1.-];K11161|2|3e-82|305|cfa:611373|retinol dehydrogenase 13 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 10178781 438.00 0.49 2.205 2.16992500144231 Up 0.484678378021397 CG42867 CG42867 - - - - 36903 1395.00 18.97 18.26 -0.0550329134272537 Down 0.138026680755514 CG6665 CG6665 - - - - 12798518 554.00 0.98 1.525 0.63795558833504 Up 0.232532030114912 CG43095 CG43095 - - - - 38159 2640.00 6.25 5.35 -0.22431729826094 Down 0.239037115308414 CG2199 CG2199, isoform C K04462|1|3e-08|60.8|ecb:100057450|ecotropic virus integration site 1 protein;K09228|3|1e-07|59.3|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 40864 2021.98 0.885 1.52 0.780321963360588 Up 0.265849953770968 CG14609 CG14609, isoform B - - - - 19835439 1705.00 9.625 7.415 -0.376339848014996 Down 0.40222559767534 246408 1428.00 0.055 0.16 1.5405683813627 Up 0.110223220182274 CG30036 CG30036 K07819|1|3e-136|485|dya:Dyak_GE13486|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-] GO:0016020//membrane GO:0016757//transferase activity, transferring glycosyl groups - 36792 841.00 11.085 7.71 -0.523806004952273 Down 0.490423986263373 CG8441 CG8441, isoform B - - - - 35088 953.00 16.195 7.94 -1.02833755565223 Down 0.65037643640206 CG5783 CG5783 - - GO:0016407//acetyltransferase activity - 36191 744.00 0.11 0.065 -0.758991900496205 Down 0.0694426099590543 Cpr47Ec cuticular protein 47Ec - - GO:0005198//structural molecule activity - 317867 2820.00 3.245 3.645 0.167700336327799 Up 0.151664245145952 CG32121 CG32121 K09237|1|1e-24|114|dwi:Dwil_GK12114|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0044464//cell part GO:0046914//transition metal ion binding - 12798001 396.04 0.305 0.365 0.259087221317131 Up 0.0724144762911108 CG43271 CG43271, isoform D - - - - 5740224 1168.00 7.645 8.63 0.17484405781815 Up 0.229428080834764 CG34317 CG34317 - - GO:0004518//nuclease activity GO:0006399//tRNA metabolic process 35359 5003.15 51.095 54.02 0.0803115194890169 Up 0.205124818385946 sky skywalker, isoform L K12587|1|1e-16|89.7|bfo:BRAFLDRAFT_124886|exosome complex component MTR3, animal type GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 41712 714.00 9.57 12.285 0.360307027876139 Up 0.424085325584467 CG9920 CG9920 K04078|1|1e-47|189|dmo:Dmoj_GI24558|chaperonin GroES - - - 42316 965.00 0.605 1.165 0.945322907379686 Up 0.258090080570598 CG31245 CG31245 K11665|1|5e-20|98.2|dwi:Dwil_GK13479|DNA helicase INO80 [EC:3.6.1.-] - - - 32657 2264.00 1.465 0.575 -1.34926680347787 Down 0.343415665037644 CG32572 CG32572 - - GO:0003824//catalytic activity GO:0008152//metabolic process 12798514 543.00 48.63 39.135 -0.313387146700089 Down 0.502971866332056 CG43091 CG43091 - - - - 32303 5488.67 3.52 4.035 0.196993244640483 Up 0.178675208030643 Neto neuropilin and tolloid-like, isoform B K09608|1|3e-23|111|oaa:100078097|tolloid-like protein 1 [EC:3.4.24.-] - - - 40301 2120.24 11.09 13.245 0.256188478207912 Up 0.353586052040682 CG3634 CG3634, isoform C - GO:0031224//intrinsic to membrane - - 41693 447.21 13.68 21.07 0.623122083931408 Up 0.592524105138027 Mst87F Male-specific RNA 87F, isoform B - - - - 36638 1821.29 133.64 80.815 -0.725656887503251 Down 0.691916523576806 Rpn6 regulatory particle non-ATPase 6, isoform C K03036|1|0.0|803|dya:Dyak_GE12293|26S proteasome regulatory subunit N6 GO:0015630//microtubule cytoskeleton;GO:0005838//proteasome regulatory particle;GO:0015630//microtubule cytoskeleton;GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 38905 3364.00 1.14 1.215 0.0919224894410388 Up 0.0627063796063928 mus301 mutagen-sensitive 301 K02349|1|3e-82|307|phu:Phum_PHUM150880|DNA polymerase theta subunit [EC:2.7.7.7] GO:0030532//small nuclear ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0032559;GO:0042623//ATPase activity, coupled GO:0006412//translation;GO:0003006//developmental process involved in reproduction;GO:0007143//female meiosis;GO:0051276//chromosome organization;GO:0065001//specification of axis polarity;GO:0006259//DNA metabolic process;GO:0006403//RNA localization;GO:0007292//female gamete generation;GO:0009948//anterior/posterior axis specification 19835018 840.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 19835864 399.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 33373 1574.89 381.345 197.69 -0.947856888735571 Down 0.730220578523313 Got2 glutamate oxaloacetate transaminase 2, isoform B K00813|1|0.0|801|dya:Dyak_GE15280|aspartate aminotransferase [EC:2.6.1.1] GO:0031980;GO:0031980 GO:0008483//transaminase activity;GO:0048037//cofactor binding;GO:0008483//transaminase activity;GO:0048037//cofactor binding GO:0043112//receptor metabolic process;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0009066//aspartate family amino acid metabolic process;GO:0043112//receptor metabolic process;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0009066//aspartate family amino acid metabolic process 37464 3322.00 14.99 16.03 0.0967740422066887 Up 0.190265486725664 CG10321 CG10321, isoform B K09228|1|1e-14|82.4|api:100159445|KRAB domain-containing zinc finger protein - - - 14462751 545.00 1.16 0.655 -0.824557993590122 Down 0.236065248976357 CG43813 CG43813 - - - - 318841 5069.03 108.07 105.11 -0.0400661580378591 Down 0.134229295997887 Bsg basigin, isoform J K06535|1|1e-14|82.4|hsa:682|basigin GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part;GO:0030863//cortical cytoskeleton;GO:0044456//synapse part - GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0002118//aggressive behavior;GO:0051640//organelle localization 33710 1177.00 122.33 117.8 -0.0544387121518061 Down 0.156122044644036 Trip1 Trip1 K03246|1|0.0|665|dse:Dsec_GM18055|translation initiation factor eIF-3 subunit 2 GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation 41760 6008.14 22.945 27.995 0.28698937330072 Up 0.451822744683661 Pde6 phosphodiesterase 6, isoform D K13763|1|0.0|1975|dme:Dmel_CG8279|cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35] - - - 36730 1562.00 11.445 11.565 0.0150478030805041 Up 0.0611544049663188 CG8207 CG8207 K00966|1|0.0|878|dme:Dmel_CG8207|mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] - GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0008152//metabolic process 42754 1974.00 0.91 1.045 0.199564491882186 Up 0.093778893144895 CG6763 CG6763, isoform B K08076|1|6e-44|179|cel:C05D11.6|astacin [EC:3.4.24.21];K08606|5|2e-39|164|tgu:100227825|meprin A, beta [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 44006 1312.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 Fad2 Fad2 K00507|1|0.0|753|dme:Dmel_CG7923|stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016215 GO:0006631//fatty acid metabolic process;GO:0006909//phagocytosis;GO:0007617//mating behavior;GO:0019748//secondary metabolic process;GO:0051301//cell division 32893 787.00 0.885 0.51 -0.795180208111502 Down 0.203176594901598 CG14191 CG14191 - - - - 19835624 293.00 0.01 0.21 4.39231742277876 Up 0.216153744551578 37403 4782.65 6.3 6.23 -0.0161196653632767 Down 0.0542200501915203 Magi magi, isoform C K05631|1|1e-84|316|tgu:100230368|atrophin-1 interacting protein 3 (BAI1-associated protein 1) - - - 31945 2671.37 4.46 4.135 -0.10915638074903 Down 0.123200369832255 CG34104 RhoU, isoform C K04392|1|6e-07|56.6|tad:TRIADDRAFT_19095|Ras-related C3 botulinum toxin substrate 1;K07866|2|2e-06|55.1|tgu:100230573|Ras homolog gene family, member V;K07865|4|2e-06|54.7|bfo:BRAFLDRAFT_73115|Ras homolog gene family, member U GO:0044464//cell part;GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction 33060 1160.89 3.22 5.875 0.867528163337745 Up 0.499042398626337 CG1324 CG1324, isoform C - - - - 32791 2114.74 14.6 13.545 -0.108207975565365 Down 0.198916919825651 CG7192 CG7192, isoform D K12186|1|6e-173|607|dme:Dmel_CG7192|ESCRT-I complex subunit MVB12 - - - 326120 1692.00 12.47 13.345 0.0978378403122965 Up 0.179963016774534 HdacX histone deacetylase X, isoform B K11418|1|0.0|639|dme:Dmel_CG31119|histone deacetylase 11 [EC:3.5.1.98] GO:0016585//chromatin remodeling complex GO:0003824//catalytic activity GO:0006476//protein deacetylation 43306 615.00 0.79 3.145 1.99313545870219 Up 0.53486989829613 CG5402 CG5402 - - - - 40509 1627.66 6.075 6.015 -0.0143196713170669 Down 0.0502575617487782 Ssl1 suppressor of Stem-Loop mutation ortholog, isoform B K03142|1|0.0|865|dme:Dmel_CG11115|transcription initiation factor TFIIH subunit H2 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006259//DNA metabolic process;GO:0006352//DNA-dependent transcription, initiation;GO:0010468//regulation of gene expression 19835313 1011.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 37167 5546.00 14.92 5.885 -1.34213321521679 Down 0.677090212653546 CG15080 CG15080 - - - - 43734 1407.00 4.68 4.37 -0.098875250082806 Down 0.11643111874257 CstF-50 CstF-50 K10599|1|2e-20|100|hmg:100209788|pre-mRNA-processing factor 19 [EC:6.3.2.19];K03130|2|8e-19|95.1|bfo:BRAFLDRAFT_65485|transcription initiation factor TFIID subunit D4 - - GO:0006397//mRNA processing 19835460 2774.00 0.06 0.08 0.415037499278844 Up 0.0547483819838859 32329 4908.83 37.67 33.645 -0.163023912139964 Down 0.327202483159424 NnaD drosophila Nna1 ortholog, isoform J - - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 38913 2097.57 42.58 43.085 0.0170097340897675 Up 0.0830801743494915 Atg18 Autophagy-specific gene 18a, isoform G - - - GO:0007552//metamorphosis;GO:0002697;GO:0007552//metamorphosis;GO:0002697;GO:0007552//metamorphosis;GO:0002697 39783 2001.88 14.44 9.23 -0.645668189241397 Down 0.563730022454101 CG4950 CG4950, isoform C K13023|1|3e-19|97.1|rno:303861|carboxypeptidase N regulatory subunit;K05401|5|1e-17|91.7|dme:Dmel_CG5195|toll-like recepto 3 - GO:0005488//binding - 31835 2612.03 3.755 4.205 0.163292892740873 Up 0.157806102232202 APC4 anaphase promoting complex subunit 4, isoform C K03351|1|0.0|1443|dme:Dmel_CG32707|anaphase-promoting complex subunit 4 - - - 19835777 641.00 0.19 0.075 -1.34103691783507 Down 0.12012944128913 39007 1380.00 0.09 0.04 -1.16992500144231 Down 0.0797781006472064 CG13310 CG13310 - - - - 37763 614.00 1.37 1.69 0.302847353321658 Up 0.155461629903579 CG15800 CG15800 K03094|1|6e-89|325|dme:Dmel_CG15800|S-phase kinase-associated protein 1 - GO:0005488//binding;GO:0019787//small conjugating protein ligase activity GO:0019941//modification-dependent protein catabolic process 35950 4092.96 71.055 99.24 0.481985562589881 Up 0.621549332981112 Pkn protein kinase related to protein kinase N, isoform R K06071|1|0.0|968|dse:Dsec_GM20615|protein kinase N [EC:2.7.11.13] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0023060 31923 577.92 656.36 504.85 -0.378632519639777 Down 0.594769515255581 CG9691 CG9691, isoform B - - - - 326226 4469.26 59.47 63.925 0.104218179752807 Up 0.246631884823669 CG32647 CG32647, isoform D - - - - 34435 2729.39 2.34 3.48 0.572578776265324 Up 0.331528199709417 CG6232 lonely heart, isoform D K08632|1|2e-42|174|tgu:100222433|a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity - 31993 871.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 Rab9Db Rab at 9Db K07976|1|3e-113|407|dme:Dmel_CG9807|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 37559 1526.77 50.175 53.875 0.102647252613844 Up 0.243197728173293 qkr58E-3 quaking related 58E-3, isoform D K13198|1|3e-38|159|gga:374071|KH domain-containing, RNA-binding, signal transduction-associated protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0012501//programmed cell death 33321 1091.00 0.605 1.455 1.26601210563369 Up 0.332287676660943 CG5561 CG5561 - - GO:0005488//binding;GO:0016741 - 32322 3040.00 4.535 4.765 0.0713736633814195 Up 0.0926231673490952 Lig4 Ligase4 K10777|1|0.0|1806|dme:Dmel_CG12176|DNA ligase 4 [EC:6.5.1.1] GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0003909//DNA ligase activity;GO:0032559 GO:0000726;GO:0006310//DNA recombination;GO:0002520//immune system development;GO:0030154//cell differentiation;GO:0009314//response to radiation;GO:0065007//biological regulation 39175 1110.66 20.2 21.235 0.0720888157082448 Up 0.161075155197464 vnc variable nurse cells, isoform E K00670|1|2e-98|359|dsi:Dsim_GD14230|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 41957 4195.13 19.095 17.045 -0.163846320482568 Down 0.287544577994981 Akt1 Akt1, isoform E K04456|1|0.0|1142|dme:Dmel_CG4006|RAC serine/threonine-protein kinase [EC:2.7.11.1] - - - 33182 903.00 30.435 27.495 -0.146562079216773 Down 0.302304847444195 mRpL10 mitochondrial ribosomal protein L10 K04237|1|6e-20|97.8|ame:726759|partitioning defective protein 3 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0022613//ribonucleoprotein complex biogenesis 32551 2218.20 4.985 3.895 -0.355970176336527 Down 0.298870690793819 CycD cyclin D, isoform F K10151|1|0.0|851|dme:Dmel_CG9096|cyclin D2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process 32154 4320.50 71.575 39.455 -0.859247625489941 Down 0.698355567296262 pot papillote, isoform C - GO:0044464//cell part;GO:0044464//cell part - GO:0007591//molting cycle, chitin-based cuticle;GO:0040003//chitin-based cuticle development;GO:0007591//molting cycle, chitin-based cuticle;GO:0040003//chitin-based cuticle development 43331 2860.46 16.475 16.93 0.0393035080002273 Up 0.105204068154801 btz barentsz, isoform D - GO:0012505//endomembrane system;GO:0044424//intracellular part;GO:0012505//endomembrane system;GO:0044424//intracellular part - GO:0019094//pole plasm mRNA localization;GO:0007017//microtubule-based process;GO:0019094//pole plasm mRNA localization;GO:0007017//microtubule-based process 19835682 1036.00 0.085 0.09 0.082462160191973 Up 0.0426627922335227 14462623 491.00 1.105 0.41 -1.43035055477335 Down 0.309602430326245 CG44163 CG44163 - - - - 326132 1474.00 15.175 22.83 0.589234343081657 Up 0.590641923127724 CG31300 CG31300 - - - - 39958 3750.41 48.245 53.195 0.140911215157911 Up 0.310758156122045 Nedd4 Nedd4, isoform M K10591|1|0.0|1748|dme:Dmel_CG42279|E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition;GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition;GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition;GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition;GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition;GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition;GO:0002090//regulation of receptor internalization;GO:0032446//protein modification by small protein conjugation;GO:0044089//positive regulation of cellular component biogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0016198//axon choice point recognition 38549 1063.00 1.105 0.18 -2.61797755794912 Down 0.384163254523841 CG15022 CG15022 - - - - 37860 6115.00 6.895 8.74 0.342082727986618 Up 0.367685906749439 CG4049 CG4049 K10876|1|0.0|2737|dme:Dmel_CG4049|RAD54-like protein 2 [EC:3.6.1.-] - GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 34364 1699.00 58.78 56.05 -0.0686109859585435 Down 0.187491744815744 me31B maternal expression at 31B, isoform B K12614|1|0.0|887|dme:Dmel_CG4916|ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13] GO:0030529//ribonucleoprotein complex;GO:0015630//microtubule cytoskeleton;GO:0030529//ribonucleoprotein complex;GO:0015630//microtubule cytoskeleton GO:0003724//RNA helicase activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0003724//RNA helicase activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0022618//ribonucleoprotein complex assembly;GO:0022618//ribonucleoprotein complex assembly 326125 835.00 119.715 74.325 -0.687684466561423 Down 0.680854576674151 CG31207 CG31207 K12347|1|7e-26|117|dan:Dana_GF18523|natural resistance-associated macrophage protein - - - 32072 2190.00 7.76 7.7 -0.0111982066048638 Down 0.0502575617487782 CG34348 CG34348 - GO:0031224//intrinsic to membrane GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 12798134 1495.00 0.18 0.175 -0.0406419844973458 Down 0.0382380134724607 38649 1940.00 7.395 8.495 0.200063800085153 Up 0.253632281072514 Myt1 Myt1 K08282|1|0.0|1049|dme:Dmel_CG32417|non-specific serine/threonine protein kinase [EC:2.7.11.1];K06633|4|9e-75|281|nve:NEMVE_v1g143837|membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1] GO:0044464//cell part GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 36377 6012.67 7.98 7.96 -0.00362031567869702 Down 0.0416061286487914 fra frazzled, isoform C K06766|1|0.0|683|mmu:18007|neogenin GO:0031224//intrinsic to membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031224//intrinsic to membrane;GO:0043005//neuron projection;GO:0044297//cell body GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0016198//axon choice point recognition;GO:0006928//cellular component movement;GO:0007431//salivary gland development;GO:0016198//axon choice point recognition;GO:0006928//cellular component movement;GO:0007431//salivary gland development 246457 710.90 8.075 8.25 0.0309318595518909 Up 0.073702285035002 CG30100 CG30100, isoform B K02835|1|9e-09|60.5|aga:AgaP_AGAP012082|peptide chain release factor RF-1 - GO:0008079//translation termination factor activity GO:0006412//translation 41090 5314.26 15.225 14.01 -0.119985272362877 Down 0.217771760665698 Kdm2 lysine (K)-specific demethylase 2, isoform E K10276|1|0.0|2331|dme:Dmel_CG11033|F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] - GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 39951 1132.00 1.42 2.485 0.807354922057604 Up 0.341302337868181 CG13733 CG13733 - - - - 2768846 896.00 0.81 1 0.3040061868901 Up 0.119369964337604 CG33458 CG33458 K01312|1|2e-27|122|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K09637|2|2e-23|109|mmu:71753|transmembrane protease, serine 6 [EC:3.4.21.-];K01321|3|4e-23|108|dre:678552|coagulation factor IX (Christmas factor) [EC:3.4.21.22];K09628|4|8e-23|107|hsa:83886|protease, serine 27 [EC:3.4.21.-];K01323|5|4e-22|105|ecb:100056603|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462670 676.00 10.87 10.77 -0.0133336904831018 Down 0.0547483819838859 36658 3477.73 56.9 61.83 0.119878353066468 Up 0.280676264694228 Inr-a inverse regulator a, isoform H K12879|1|3e-28|129|tad:TRIADDRAFT_56575|THO complex subunit 2 - GO:0003676//nucleic acid binding;GO:0003711//transcription elongation regulator activity;GO:0003676//nucleic acid binding;GO:0003711//transcription elongation regulator activity;GO:0003676//nucleic acid binding;GO:0003711//transcription elongation regulator activity;GO:0003676//nucleic acid binding;GO:0003711//transcription elongation regulator activity GO:0006397//mRNA processing;GO:0006397//mRNA processing;GO:0006397//mRNA processing;GO:0006397//mRNA processing;GO:0015031//protein transport 37142 2405.00 8.495 12.285 0.532212005177944 Up 0.506901334037776 sec6 Sec6 ortholog K06110|1|0.0|1367|dme:Dmel_CG5341|exocyst complex component 3 - - - 41230 2061.00 31.68 32.225 0.0246080231694038 Up 0.0838726720380399 CG3925 CG3925 K11793|1|0.0|1128|dme:Dmel_CG3925|cereblon - - - 37285 1984.00 21.345 18.87 -0.177803739647193 Down 0.318716153744552 CG11208 CG11208 K12261|1|0.0|1105|dme:Dmel_CG11208|2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-] - - - 38448 401.00 16.89 18.95 0.166028520257068 Up 0.296129969620922 Acp63F accessory gland protein 63F - - - - 31143 1099.64 9.575 9.105 -0.072613469835481 Down 0.126205256901334 Pgam5 phosphoglycerate mutase 5, isoform B K01834|1|8e-55|214|mcc:693782|phosphoglycerate mutase [EC:5.4.2.1];K13347|2|9e-54|210|ecb:100061603|peroxisomal membrane protein 2 - - - 37858 5108.00 22.275 23.12 0.0537159660913943 Up 0.131983885880333 gek genghis khan K08286|1|0.0|3185|dme:Dmel_CG4012|protein-serine/threonine kinase [EC:2.7.11.-] - GO:0043169//cation binding;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0032559 GO:0007015//actin filament organization;GO:0023033;GO:0030832//regulation of actin filament length;GO:0006464//cellular protein modification process 40838 1152.95 5.09 8.47 0.734696313256503 Up 0.521595562012944 dj don juan, isoform C K11423|1|3e-08|59.7|dgr:Dgri_GH16034|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43];K13100|4|5e-08|58.9|dan:Dana_GF14847|pre-mRNA-splicing factor CWC22 GO:0019861//flagellum;GO:0005739//mitochondrion;GO:0019861//flagellum;GO:0005739//mitochondrion GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation 33281 5139.81 9.485 10.525 0.150100554542283 Up 0.225531633866068 S star, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0009888//tissue development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051605;GO:0030534//adult behavior;GO:0007389//pattern specification process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0007445;GO:0046666//retinal cell programmed cell death;GO:0007472//wing disc morphogenesis;GO:0009888//tissue development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0051605;GO:0030534//adult behavior;GO:0007389//pattern specification process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0006464//cellular protein modification process;GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0007445;GO:0046666//retinal cell programmed cell death;GO:0007472//wing disc morphogenesis 42692 928.00 0.55 1.23 1.16115479181458 Up 0.294710077928939 Takl2 Tak1-like 2 K04427|1|8e-80|296|dpe:Dper_GL23779|mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] - GO:0032559;GO:0004709//MAP kinase kinase kinase activity GO:0000186//activation of MAPKK activity;GO:0012501//programmed cell death;GO:0007389//pattern specification process;GO:0009886//post-embryonic morphogenesis;GO:0002252;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0002780 40935 2105.00 4.88 3.655 -0.417009741610449 Down 0.32426363756439 Prat phosphoribosylamidotransferase, isoform B K00764|1|0.0|1025|dme:Dmel_CG2867|amidophosphoribosyltransferase [EC:2.4.2.14] - GO:0043169//cation binding;GO:0016763//transferase activity, transferring pentosyl groups GO:0006144//purine nucleobase metabolic process;GO:0006188//IMP biosynthetic process;GO:0010259//multicellular organismal aging;GO:0007292//female gamete generation;GO:0009792//embryo development ending in birth or egg hatching 31691 3612.00 0.02 0.01 -1 Down 0.0497292299564126 dec-1 defective chorion 1, isoform G - - - - 8674023 674.00 0.3 0.4 0.415037499278844 Up 0.0948685774666491 CG42535 CG42535 - - - - 32695 1978.85 28.455 24.825 -0.196888461716895 Down 0.361973319244486 CG4991 CG4991, isoform F - GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0006865//amino acid transport;GO:0006865//amino acid transport;GO:0006865//amino acid transport 32650 895.00 0.785 1.26 0.682659174608289 Up 0.221139875842029 CG4653 CG4653 K01362|1|7e-41|167|dme:Dmel_CG2071| [EC:3.4.21.-];K01312|2|3e-26|118|dpo:Dpse_GA11574|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31372 1946.00 0.475 0.58 0.288125386796625 Up 0.0926892088231409 CG12692 CG12692, isoform C K10477|1|4e-06|53.5|dre:565970|BTB/POZ domain-containing protein 1/2 - - - 19835021 1429.00 19.49 22.81 0.226932356054247 Up 0.377493065645225 38586 13807.00 0.165 0.31 0.909802191028422 Up 0.126238277638357 CG17150 CG17150, isoform E K10408|1|0.0|8273|dya:Dyak_GE21470|dynein heavy chain, axonemal GO:0005875//microtubule associated complex;GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 39273 1081.64 1.64 1.75 0.0936591072142449 Up 0.072810725135385 CG6168 CG6168, isoform C K00683|1|8e-73|273|dpo:Dpse_GA19273|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] - GO:0016787//hydrolase activity GO:0019538//protein metabolic process 34937 4219.00 0.15 0.1 -0.584962500721156 Down 0.075023114515916 Tep1 Thioester-containing protein 1 K06530|1|0.0|1211|dme:Dmel_CG7052|CD109 antigen GO:0044421//extracellular region part GO:0005488//binding;GO:0061135 GO:0042742//defense response to bacterium;GO:0006909//phagocytosis 37449 1299.39 72.395 56.31 -0.362498909342571 Down 0.554847444194954 Fkbp13 FK506-binding protein 14 ortholog, isoform F K09577|1|3e-128|458|dsi:Dsim_GD25197|FK506-binding protein 14 [EC:5.2.1.8] - - - 39641 1388.00 0.28 0.625 1.15842936260448 Up 0.205587108704266 Or71a odorant receptor 71a, isoform D K08471|1|0.0|758|dme:Dmel_CG17871|gustatory receptor GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004930//G-protein coupled receptor activity GO:0007606//sensory perception of chemical stimulus 38229 402.00 15.01 11.95 -0.328913358752578 Down 0.428278959186369 CG2021 CG2021 K12627|1|2e-48|190|dya:Dyak_GE20916|U6 snRNA-associated Sm-like protein LSm8 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0005488//binding GO:0000377 32605 1533.19 11.935 12.175 0.0287232058879283 Up 0.0799762250693435 CG9992 CG9992, isoform E - - - - 34106 1165.00 27.1 29.475 0.121198961625891 Up 0.256703209615639 CG12375 CG12375 K01069|1|5e-07|55.5|api:100160603|hydroxyacylglutathione hydrolase [EC:3.1.2.6] - GO:0003824//catalytic activity - 38501 2732.00 5.97 7.615 0.351113105222487 Up 0.352859595826179 Teh4 tipE homolog 4 - GO:0031224//intrinsic to membrane - GO:0010765//positive regulation of sodium ion transport 39655 1862.00 14.72 16.87 0.196682302230553 Up 0.321390833443402 Prp31 Prp31 K12844|1|0.0|790|dme:Dmel_CG6876|U4/U6 small nuclear ribonucleoprotein PRP31 GO:0035097//histone methyltransferase complex GO:0005488//binding - 41979 1653.00 0.14 0.17 0.280107919192735 Up 0.0592061814819707 CG17930 CG17930 K07593|1|9e-09|62.0|mmu:20526|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2 - - - 32921 1633.00 6.795 8.615 0.342377245457557 Up 0.365572579579976 CG8010 CG8010 - - - - 44117 2501.00 37.415 54.195 0.534542980375505 Up 0.621549332981112 bgm bubblegum, isoform C K01897|1|1e-56|221|spu:581020|long-chain acyl-CoA synthetase [EC:6.2.1.3] - GO:0015645//fatty acid ligase activity GO:0006631//fatty acid metabolic process 3772191 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33854 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 41150 1755.00 41.3 44.18 0.0972516370484672 Up 0.236890767401928 AP-47 adaptor protein complex 1, mu subunit K12393|1|0.0|818|dya:Dyak_GE24766|AP-1 complex subunit mu GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding GO:0006901//vesicle coating;GO:0051704;GO:0001505//regulation of neurotransmitter levels;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 53445 506.00 7.54 8.805 0.223758480562544 Up 0.276977942147669 Roc1b Roc1b K03868|1|9e-67|251|dme:Dmel_CG16988|RING-box protein 1 - GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0048870//cell motility;GO:0010876//lipid localization;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032446//protein modification by small protein conjugation 37275 2378.23 27.375 14.32 -0.934827472111642 Down 0.670188878615771 CG8654 CG8654, isoform D K08202|1|8e-76|285|dme:Dmel_CG6331|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - - 42642 2009.00 94 98.64 0.069512042950477 Up 0.194062871483292 AP-50 adaptor protein complex 2, mu subunit, isoform C K11826|1|0.0|870|dgr:Dgri_GH22222|AP-2 complex subunit mu-1 GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030139//endocytic vesicle;GO:0005905//coated pit;GO:0044439;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030139//endocytic vesicle;GO:0005905//coated pit;GO:0044439;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030139//endocytic vesicle;GO:0005905//coated pit;GO:0044439 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006901//vesicle coating;GO:0050658//RNA transport;GO:0001505//regulation of neurotransmitter levels;GO:0050688//regulation of defense response to virus;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0050658//RNA transport;GO:0001505//regulation of neurotransmitter levels;GO:0050688//regulation of defense response to virus;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0050658//RNA transport;GO:0001505//regulation of neurotransmitter levels;GO:0050688//regulation of defense response to virus;GO:0015031//protein transport 36773 5809.81 22.9 21.495 -0.0913464880010045 Down 0.195879012019548 Dg dystroglycan, isoform D K06265|1|0.0|1261|dme:Dmel_CG18250|dystroglycan 1 GO:0016010//dystrophin-associated glycoprotein complex;GO:0016323//basolateral plasma membrane;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016323//basolateral plasma membrane;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016323//basolateral plasma membrane;GO:0042383//sarcolemma;GO:0045202//synapse GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0045924//regulation of female receptivity;GO:0003002//regionalization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0019725//cellular homeostasis;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0006935//chemotaxis;GO:0050804//regulation of synaptic transmission;GO:0031032//actomyosin structure organization;GO:0045924//regulation of female receptivity;GO:0003002//regionalization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0019725//cellular homeostasis;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0006935//chemotaxis;GO:0050804//regulation of synaptic transmission;GO:0031032//actomyosin structure organization;GO:0045924//regulation of female receptivity;GO:0003002//regionalization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0019725//cellular homeostasis;GO:0007309//oocyte axis specification;GO:0007619//courtship behavior;GO:0006935//chemotaxis;GO:0050804//regulation of synaptic transmission;GO:0031032//actomyosin structure organization 318176 588.00 0.62 0.235 -1.39960745870924 Down 0.225498613129045 CG32727 CG32727 K09539|1|1e-09|62.4|xla:100049122|DnaJ homolog subfamily C member 19 - GO:0005515//protein binding - 318794 952.00 62.95 52.75 -0.255035284124469 Down 0.464238541804253 CG31548 CG31548 K11147|1|2e-24|113|dmo:Dmoj_GI11985|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 35963 2183.08 153.725 156.535 0.0261334617193169 Up 0.113360190199445 CG8801 putative nucleolar protein 1, isoform B K03979|1|7e-09|62.8|dre:100001905|GTP-binding protein GO:0043231//intracellular membrane-bounded organelle GO:0032561//guanyl ribonucleotide binding - 31106 1079.43 519.085 497.31 -0.0618253573645585 Down 0.184189671113459 sta stubarista, isoform F K02998|1|1e-141|502|dya:Dyak_GE16523|small subunit ribosomal protein SAe - - - 39795 624.00 89.38 51.05 -0.808041083629846 Down 0.696902654867257 CG13044 CG13044 - - - - 40783 837.00 0.195 0.115 -0.761840262805235 Down 0.0923590014529124 Hr83 hormone receptor 83 K08709|1|1e-135|482|dme:Dmel_CG10296|nuclear receptor, other families, insect GO:0043231//intracellular membrane-bounded organelle GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 41520 1758.00 205.51 186.14 -0.142820483977577 Down 0.335094439307885 Cyp9f2 Cyp9f2 K07424|1|0.0|1023|dme:Dmel_CG11466|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] - - - 318935 416.57 0.885 0.995 0.169019070460652 Up 0.0841698586712455 CG31775 CG31775, isoform B - - - - 38807 2394.00 11.905 10.965 -0.118661808596741 Down 0.198256505085193 CG8605 RINT1 ortholog - - - - 39485 1490.40 30.895 28.09 -0.137316748976604 Down 0.289756967375512 Syx13 syntaxin 13, isoform B K13814|1|3e-21|103|tgu:100218457|t-SNARE domain-containing protein 1;K08488|2|2e-18|94.0|bfo:BRAFLDRAFT_59863|syntaxin 7;K13813|4|4e-17|89.7|xtr:407856|syntaxin 12/13 GO:0016020//membrane GO:0005515//protein binding GO:0001505//regulation of neurotransmitter levels;GO:0007126//meiosis;GO:0033206//cytokinesis after meiosis;GO:0006810//transport;GO:0000087//M phase of mitotic cell cycle 40726 1118.00 0.31 0.35 0.175086706558091 Up 0.0605270109628847 glob3 globin 3 - - GO:0005506//iron ion binding GO:0015669//gas transport 319000 834.00 1.035 1.265 0.289506617194985 Up 0.127955355963545 CG31882 CG31882 - - - - 39408 437.00 13.515 13.985 0.0493187419414967 Up 0.114119667150971 CG10418 CG10418 K12621|1|2e-48|190|dvi:Dvir_GJ13149|U6 snRNA-associated Sm-like protein LSm2 GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0019900//kinase binding;GO:0017069//snRNA binding GO:0006401//RNA catabolic process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000387//spliceosomal snRNP assembly 39083 1769.72 33.105 34.99 0.0798935342390794 Up 0.19416193369436 CG3689 CG3689, isoform C K10636|1|4e-77|289|gga:415697|autocrine motility factor receptor [EC:6.3.2.19] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0006397//mRNA processing;GO:0006397//mRNA processing 39738 1329.00 43.51 24.575 -0.824155600312587 Down 0.676264694227975 CG10516 CG10516 K10345|1|0.0|711|dme:Dmel_CG10516|SPRY domain-containing SOCS box protein 3 - - - 44849 2786.00 1.03 1.05 0.0277449904829039 Up 0.0445449742438251 pnr pannier, isoform D K09183|1|0.0|724|dme:Dmel_CG3978|GATA-binding protein 4/5/6 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009880//embryonic pattern specification;GO:0009888//tissue development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006355//regulation of transcription, DNA-dependent;GO:0048534;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009887//organ morphogenesis;GO:0042684//cardioblast cell fate commitment;GO:0003015//heart process;GO:0009880//embryonic pattern specification;GO:0009888//tissue development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006355//regulation of transcription, DNA-dependent;GO:0048534;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009887//organ morphogenesis;GO:0042684//cardioblast cell fate commitment;GO:0003015//heart process 31129 2358.26 18.765 24.185 0.366068247558887 Up 0.500627394003434 Scgdelta sarcoglycan delta, isoform E K12563|1|1e-42|174|dre:324961|delta-sarcoglycan;K12564|2|1e-42|174|xtr:780370|gamma-sarcoglycan GO:0031224//intrinsic to membrane;GO:0030016//myofibril;GO:0016011//dystroglycan complex;GO:0031224//intrinsic to membrane;GO:0030016//myofibril;GO:0016011//dystroglycan complex;GO:0031224//intrinsic to membrane;GO:0030016//myofibril;GO:0016011//dystroglycan complex - GO:0031032//actomyosin structure organization;GO:0003015//heart process;GO:0009888//tissue development;GO:0031032//actomyosin structure organization;GO:0003015//heart process;GO:0009888//tissue development;GO:0031032//actomyosin structure organization;GO:0003015//heart process;GO:0009888//tissue development 39210 1471.05 12.215 10.32 -0.243210892844002 Down 0.329018623695681 CG8003 CG8003, isoform B K10799|1|2e-09|63.9|bmy:Bm1_32600|tankyrase [EC:2.4.2.30];K10330|5|1e-08|61.2|rno:315287|ankyrin repeat and SOCS box protein 8 - GO:0046914//transition metal ion binding - 47874 2567.00 7.79 7.88 0.0165723013947073 Up 0.0573900409457139 mit(1)15 Zeste-white 10 K11578|1|0.0|1401|dse:Dsec_GM19232|centromere/kinetochore protein ZW10 GO:0043231//intracellular membrane-bounded organelle;GO:0005876//spindle microtubule;GO:0000777//condensed chromosome kinetochore - GO:0051322//anaphase;GO:0007126//meiosis;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0000819//sister chromatid segregation 42961 1738.00 31.93 30.7 -0.0566738973125518 Down 0.156386210540219 CG13636 sosie, isoform C - - - - 3772257 504.00 0.085 0.31 1.86673346913654 Up 0.172533350944393 CG33626 CG33626 - - - - 43630 1882.16 278.48 313.645 0.171558844804875 Up 0.384790648527275 jdp jdp, isoform C K09532|1|6e-63|239|dme:Dmel_CG2239|DnaJ homolog subfamily C member 12 - GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 326188 2074.00 8.585 16.44 0.937320259679548 Up 0.636970017170783 S-Lap4 Sperm-Leucylaminopeptidase 4 K01255|1|0.0|1076|dme:Dmel_CG32064|leucyl aminopeptidase [EC:3.4.11.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 38702 543.00 15.37 5.42 -1.5037524083369 Down 0.692246730947035 Lcp65Ag2 Lcp65Ag2 - - GO:0005214//structural constituent of chitin-based cuticle GO:0002168//instar larval development 33450 1363.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 Or23a odorant receptor 23a K08471|1|0.0|702|dme:Dmel_CG9880|gustatory receptor GO:0043005//neuron projection;GO:0031224//intrinsic to membrane;GO:0044297//cell body GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 12798157 729.00 0.06 0.065 0.115477217419936 Up 0.0441487253995509 CG43153 CG43153 - - - - 34140 4972.00 11.205 10.675 -0.0699065790025406 Down 0.131686699247127 CG7806 CG7806 K10835|1|0.0|2640|dme:Dmel_CG7806|xenobiotic-transporting ATPase [EC:3.6.3.44];K05674|2|0.0|832|nve:NEMVE_v1g88546|ATP-binding cassette, subfamily C (CFTR/MRP), member 10 GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 38161 1070.71 10.885 14.76 0.439351313872189 Up 0.489895654471008 312 312, isoform B - - - - 41299 1373.34 0.385 0.595 0.628031222613042 Up 0.139776779817726 CG14693 CG14693, isoform F - - - - 42481 5539.35 54.465 73.15 0.425528433504486 Up 0.591302337868181 Calx Na/Ca-exchange protein, isoform I K05849|1|0.0|1801|dme:Dmel_CG5685|solute carrier family 8 (sodium/calcium exchanger) GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity GO:0070838//divalent metal ion transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0007165//signal transduction 42344 1139.00 0.115 0.04 -1.52356195605701 Down 0.0933166028265751 CG31219 CG31219, isoform B K01362|1|4e-45|182|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|7e-39|161|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 53544 3206.00 0.01 0.02 1 Up 0.0497292299564126 CG42296 CG42296 - - GO:0030247//polysaccharide binding GO:0006022 36417 1947.00 5.96 3.17 -0.910829490322755 Down 0.509708096684718 CG3790 CG3790 K08202|1|8e-89|328|cel:F52F12.1|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 12797991 629.00 0.64 0.645 0.0112272554232541 Up 0.041044776119403 19835663 308.00 0.455 1.105 1.28010791919274 Up 0.292959978866728 40363 1769.40 4.29 5.475 0.35188131698899 Up 0.307885352001057 ebd2 earthbound 2, isoform B - GO:0044427//chromosomal part GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression 14462917 904.00 0.22 0.15 -0.552541023028779 Down 0.0842359001452912 37488 687.00 4.21 2.335 -0.850397683356734 Down 0.440166424514595 CG4363 CG4363 - - - - 43298 5887.00 0.645 0.78 0.274174963438994 Up 0.0995575221238938 CG42534 CG42534, isoform D K10380|1|2e-31|139|dan:Dana_GF23770|ankyrin - - - 44096 4217.00 18.73 22.405 0.25846982690946 Up 0.406056003169991 wit wishful thinking, isoform B K04671|1|2e-154|547|aag:AaeL_AAEL004165|bone morphogenetic protein receptor type-2 [EC:2.7.11.30] GO:0016020//membrane GO:0005024//transforming growth factor beta-activated receptor activity;GO:0032559 GO:0048741//skeletal muscle fiber development;GO:0048812//neuron projection morphogenesis;GO:0007268//synaptic transmission;GO:0006464//cellular protein modification process 43463 2707.00 18.785 10.065 -0.900233943720431 Down 0.642220314357416 CG11951 CG11951, isoform B K11140|1|0.0|1624|dme:Dmel_CG11951|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 41446 1577.00 1.015 0.82 -0.307783912567092 Down 0.120096420552107 aur aurora K11481|1|0.0|728|dme:Dmel_CG3068|aurora kinase A [EC:2.7.11.1] GO:0005815//microtubule organizing center GO:0004672//protein kinase activity;GO:0032559 GO:0051960//regulation of nervous system development;GO:0051293//establishment of spindle localization;GO:0008105//asymmetric protein localization;GO:0051297//centrosome organization;GO:0007067//mitosis;GO:0006464//cellular protein modification process 14462647 1190.00 0.065 0.09 0.46948528330122 Up 0.0617157574957073 39289 1958.00 0.28 0.19 -0.559427408614019 Down 0.0934156650376436 CG7512 CG7512 K10587|1|5e-11|69.7|dvi:Dvir_GJ11295|ubiquitin-protein ligase E3 A [EC:6.3.2.19] GO:0044464//cell part GO:0046914//transition metal ion binding - 43904 2732.17 67.24 76.355 0.183402908401119 Up 0.379375247655528 SNF1A AMP-activated protein kinase alpha subunit, isoform C K07198|1|0.0|1051|dsi:Dsim_GD16554|5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0016049//cell growth;GO:0023060;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044057;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0023060;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044057;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0023060;GO:0007049//cell cycle;GO:0006909//phagocytosis;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0044057;GO:0006464//cellular protein modification process 35407 3624.00 13.21 4.675 -1.49859219647183 Down 0.680194161933694 CG8665 CG8665 K00289|1|0.0|1800|dme:Dmel_CG8665|formyltetrahydrofolate dehydrogenase [EC:1.5.1.6] GO:0044424//intracellular part GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0005488//binding;GO:0022892;GO:0016741 GO:0009256//10-formyltetrahydrofolate metabolic process 31848 1882.31 406.68 403.965 -0.00966374104945183 Down 0.0703671905956941 His3.3B histone H3.3B, isoform E K11253|1|6e-65|248|bmy:Bm1_40030|histone H3 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0065008;GO:0007417//central nervous system development;GO:0007126//meiosis;GO:0009719;GO:0002164//larval development;GO:0033554//cellular response to stress;GO:0010259//multicellular organismal aging;GO:0040009//regulation of growth rate;GO:0009653//anatomical structure morphogenesis;GO:0034728//nucleosome organization;GO:0009790//embryo development;GO:0065008;GO:0007417//central nervous system development;GO:0007126//meiosis;GO:0009719;GO:0002164//larval development;GO:0033554//cellular response to stress;GO:0010259//multicellular organismal aging;GO:0040009//regulation of growth rate;GO:0009653//anatomical structure morphogenesis;GO:0034728//nucleosome organization;GO:0009790//embryo development;GO:0065008;GO:0007417//central nervous system development;GO:0007126//meiosis;GO:0009719;GO:0002164//larval development;GO:0033554//cellular response to stress;GO:0010259//multicellular organismal aging;GO:0040009//regulation of growth rate;GO:0009653//anatomical structure morphogenesis;GO:0034728//nucleosome organization;GO:0009790//embryo development 38427 4147.33 1.785 2.085 0.224123309415564 Up 0.137927618544446 armi armitage, isoform D K13983|1|9e-126|452|bfo:BRAFLDRAFT_215302|putative helicase MOV10L1 [EC:3.6.4.13] GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part GO:0004386//helicase activity;GO:0005488//binding;GO:0004386//helicase activity;GO:0005488//binding GO:0000226//microtubule cytoskeleton organization;GO:0017148//negative regulation of translation;GO:0007613//memory;GO:0007315//pole plasm assembly;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0044087;GO:0000226//microtubule cytoskeleton organization;GO:0017148//negative regulation of translation;GO:0007613//memory;GO:0007315//pole plasm assembly;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0044087 43151 911.00 0.26 0.01 -4.70043971814109 Down 0.247061154404966 E(spl)mgamma-HLH enhancer of split mgamma, helix-loop-helix K09090|1|1e-101|369|der:Dere_GG11450|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0001654//eye development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007166//cell surface receptor signaling pathway 40785 4286.40 19.96 24.615 0.302426018897609 Up 0.452285035001981 CG42724 CG42724, isoform M K12824|1|0.0|932|dsi:Dsim_GD19549|transcription elongation regulator 1 - GO:0005488//binding - 12797974 733.00 0.605 1.77 1.5487423128084 Up 0.396942279751684 14462631 1207.69 0.305 0.68 1.15672550368745 Up 0.218696341302338 CG43777 CG43777, isoform C - - - - 35491 667.61 2.38 2.42 0.0240454739666509 Up 0.0488046493197728 CG10396 CG10396, isoform B K02263|1|7e-102|369|dme:Dmel_CG10396|cytochrome c oxidase subunit IV [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0022904//respiratory electron transport chain 14462393 1087.00 1.22 2.735 1.16465968522967 Up 0.424976885484084 318868 480.78 1.115 2.59 1.21590838776625 Up 0.421740853255845 CG31644 CG31644, isoform C K02268|1|3e-38|156|dme:Dmel_CG31644|cytochrome c oxidase subunit VIc [EC:1.9.3.1] - GO:0015002//heme-copper terminal oxidase activity - 37533 1195.00 3.115 3.1 -0.00696394774976458 Down 0.0432901862369568 CG11170 CG11170, isoform D - - GO:0017111//nucleoside-triphosphatase activity - 35315 2184.00 2.28 2.39 0.0679767938160069 Up 0.0701030246995113 cdc23 cell division cycle 23 ortholog, isoform B K03355|1|0.0|1227|dme:Dmel_CG2508|anaphase-promoting complex subunit 8 GO:0000152//nuclear ubiquitin ligase complex - GO:0006909//phagocytosis;GO:0007088//regulation of mitosis 36905 2578.75 307.325 305.015 -0.0108849376280258 Down 0.0702351076476027 Cbp53E calbindin 53E, isoform B K02183|1|6e-08|60.1|spu:575430|calmodulin;K05865|2|1e-07|58.9|dre:415175|troponin C, slow skeletal and cardiac muscles - - - 34686 5495.39 45.825 44.075 -0.056174311219704 Down 0.164278166688681 MRP Multidrug-Resistance like protein 1, isoform Q K05667|1|0.0|1438|xtr:100135090|ATP-binding cassette, subfamily C (CFTR/MRP), member 3;K05665|2|0.0|1417|oaa:100087202|ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0015405;GO:0005253//anion channel activity;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 39559 1228.07 6.98 5.985 -0.22187578926615 Down 0.250033020737023 CG6833 CG6833, isoform B K01175|1|2e-44|180|tgu:100229203| [EC:3.1.-.-] GO:0044464//cell part;GO:0044464//cell part GO:0004518//nuclease activity;GO:0005488//binding;GO:0004518//nuclease activity;GO:0005488//binding - 32124 1762.12 67.955 50.57 -0.426297927197389 Down 0.58932109364681 prtp pretaporter, isoform D K13984|1|0.0|852|dme:Dmel_CG1837|thioredoxin domain-containing protein 5 - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis 35907 979.00 2.255 1.9 -0.247128014924433 Down 0.155131422533351 CG13747 CG13747 - - - - 31939 1570.00 93.62 48.685 -0.943339423112111 Down 0.714502707700436 Yp1 yolk protein 1, isoform B K01059|1|2e-29|130|dpo:Dpse_GA19044|lipoprotein lipase [EC:3.1.1.34];K01046|4|3e-15|83.6|nve:NEMVE_v1g83175|triacylglycerol lipase [EC:3.1.1.3] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton - GO:0007028//cytoplasm organization;GO:0003006//developmental process involved in reproduction;GO:0044238//primary metabolic process 36746 8879.02 18.96 22.46 0.244398963502342 Up 0.388257825914674 sli slit, isoform F K06850|1|0.0|2812|dme:Dmel_CG8355|slit 3;K06839|2|0.0|1237|hsa:9353|slit 2 GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016477//cell migration;GO:0016337//cell-cell adhesion;GO:0016198//axon choice point recognition;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0001707//mesoderm formation;GO:0016477//cell migration;GO:0016337//cell-cell adhesion;GO:0016198//axon choice point recognition;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0001707//mesoderm formation;GO:0016477//cell migration;GO:0016337//cell-cell adhesion;GO:0016198//axon choice point recognition;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0001707//mesoderm formation;GO:0016477//cell migration;GO:0016337//cell-cell adhesion;GO:0016198//axon choice point recognition;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0001707//mesoderm formation;GO:0016477//cell migration;GO:0016337//cell-cell adhesion;GO:0016198//axon choice point recognition;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0001707//mesoderm formation 43448 1132.00 10.2 10.335 0.0189692365665898 Up 0.063333773609827 Slbp Stem-loop binding protein - GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0008334//histone mRNA metabolic process 19835367 717.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 40132 1393.00 7.705 9.025 0.228131975259748 Up 0.285893541143838 CG14100 CG14100 - GO:0015630//microtubule cytoskeleton GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0010467//gene expression 34073 5618.65 5.35 6.69 0.322467319352952 Up 0.31927750627394 CG14535 CG14535, isoform B K10404|1|0.0|1894|dme:Dmel_CG14535|kinesin family member 26 GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 32914 3885.52 0.95 0.385 -1.30306906763605 Down 0.273180557390041 CG7884 CG7884, isoform B - - - - 42371 3252.12 16.72 17.18 0.039155189057581 Up 0.105831462158235 RhoGAP92B Rho GTPase activating protein at 92B, isoform E K07526|1|2e-15|85.1|hmg:100210201|SLIT-ROBO Rho GTPase activating protein;K13736|2|2e-14|81.6|dre:692277|Rho GTPase-activating protein 10;K10360|3|4e-14|80.9|oaa:100075292|myosin IX GO:0044424//intracellular part GO:0005488//binding GO:0023060 39096 1126.00 8.62 8.265 -0.0606730497967845 Down 0.10959582617884 CG3437 CG3437 - - - - 318102 3280.00 28.835 18.325 -0.654007824035946 Down 0.622771100250958 drd drop dead K00680|1|4e-44|180|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups GO:0007588//excretion;GO:0006970//response to osmotic stress;GO:0007292//female gamete generation;GO:0042335//cuticle development 40671 652.39 18.84 21.32 0.178408473146392 Up 0.318947298903712 CG14671 CG14671, isoform B - - - - 39500 1085.00 0.37 0.055 -2.75002174699165 Down 0.226852463346982 CG14110 CG14110 - - - - 34449 1655.64 4.885 4.305 -0.182345324571541 Down 0.184123629639414 Lrr47 Leucine-rich repeat 47, isoform B K10348|1|0.0|823|dme:Dmel_CG6098|LRR-repeat protein 1 GO:0005624//membrane fraction;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0007264//small GTPase mediated signal transduction 12797984 1787.38 0.14 0.145 0.0506260730699681 Up 0.0419363360190199 3771825 507.00 0.165 0.01 -4.04439411935845 Down 0.184883106590939 CG33654 CG33654 K09255|1|7e-22|102|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|6e-10|63.2|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 39528 1878.00 3.48 0.435 -3 Down 0.611246863029983 CG8757 CG8757 K11166|1|2e-12|72.8|mdo:100017149|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-];K11539|2|4e-12|71.6|mdo:100015144|carbonyl reductase 4 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 32510 16562.32 13.015 14.335 0.139366592836411 Up 0.240291903315282 CG8184 CG8184, isoform H K10592|1|0.0|7907|dme:Dmel_CG8184|E3 ubiquitin-protein ligase HUWE1 [EC:6.3.2.19] GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification 40474 806.00 0.2 0.6 1.58496250072116 Up 0.237683265090477 CG11404 CG11404, isoform B - - - - 41730 1049.00 1.765 2.545 0.527997472804515 Up 0.273279619601109 CG9624 CG9624 - - - - 42509 2432.11 46.865 29.02 -0.69146336331517 Down 0.654570070003963 Ubpy UBPY ortholog, isoform B K11839|1|0.0|1703|dme:Dmel_CG5798|ubiquitin carboxyl-terminal hydrolase 8 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process 33693 2263.00 22.115 19.705 -0.16646349276082 Down 0.308942015585788 CG3008 CG3008 K08286|1|0.0|1129|dme:Dmel_CG3008|protein-serine/threonine kinase [EC:2.7.11.-];K08872|2|0.0|947|dpo:Dpse_GA15630|RIO kinase 3 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 3355048 1098.00 9.675 11.65 0.26799638850987 Up 0.348203671905957 CG40378 CG40378 K06772|1|1e-23|110|ptr:460600|limbic system-associated membrane protein;K06775|3|2e-23|110|xtr:100127726|neuronal growth regulator 1 GO:0044464//cell part GO:0046914//transition metal ion binding - 43066 1527.00 27.585 26.085 -0.0806635471053505 Down 0.185972790912693 CG10562 CG10562 - - - - 40768 1454.00 0.08 0.075 -0.093109404391481 Down 0.0382380134724607 CG15594 CG15594 - - - - 31303 690.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 Pig1 Pre-intermoult gene 1 - - - - 36701 1072.00 0.18 0.125 -0.526068811667588 Down 0.0745278034605732 CG8160 CG8160 - - - - 35914 2082.00 1.44 0.27 -2.41503749927884 Down 0.42273147536653 CG8083 CG8083, isoform C K11536|1|0.0|1008|dme:Dmel_CG8083|pyrimidine nucleoside transport protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005337//nucleoside transmembrane transporter activity;GO:0005488//binding;GO:0005337//nucleoside transmembrane transporter activity;GO:0005488//binding;GO:0005337//nucleoside transmembrane transporter activity;GO:0005488//binding GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 3772186 1400.35 7.895 6.58 -0.262851682124996 Down 0.296030907409853 CG33695 CG33695, isoform F - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 35145 671.00 28.585 37.835 0.4044631548585 Up 0.549564126271298 mRpL13 mitochondrial ribosomal protein L13 K02871|1|5e-106|382|dme:Dmel_CG10603|large subunit ribosomal protein L13 GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 32244 1458.03 21.465 19.3 -0.153385325292381 Down 0.283615110289262 CG4645 CG4645, isoform C - - - - 19835437 359.00 0.01 0.46 5.52356195605701 Up 0.343448685774666 34497 2398.00 0.23 0.345 0.584962500721156 Up 0.106161669528464 CG17139 CG17139 K05862|1|2e-24|114|dvi:Dvir_GJ17632|voltage-dependent anion channel GO:0031966//mitochondrial membrane GO:0005244//voltage-gated ion channel activity GO:0006811//ion transport 40305 3167.83 115.465 97.58 -0.242798216696508 Down 0.460276053361511 Pka-R1 cAMP-dependent protein kinase R1, isoform Z K04739|1|0.0|705|dmo:Dmoj_GI16562|cAMP-dependent protein kinase regulator GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0000166//nucleotide binding;GO:0019887//protein kinase regulator activity GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning;GO:0006468//protein phosphorylation;GO:0018988;GO:0030036//actin cytoskeleton organization;GO:0007268//synaptic transmission;GO:0007017//microtubule-based process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008306//associative learning 33738 1208.00 107.785 66.885 -0.688401812573745 Down 0.678972394663849 Rpn11 regulatory particle non-ATPase 11 K03030|1|3e-176|617|dya:Dyak_GE18698|26S proteasome regulatory subunit N11 GO:0015630//microtubule cytoskeleton;GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 32584 1176.00 90.725 52.92 -0.77768709008802 Down 0.693204332320697 Pros28.1 proteasome alpha4 subunit K02731|1|2e-127|455|dme:Dmel_CG3422|20S proteasome subunit alpha 4 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 42289 6189.16 18.95 24.165 0.350721146369271 Up 0.488211596882842 cdi center divider, isoform B K08287|1|0.0|2081|dme:Dmel_CG6027|dual-specificity kinase [EC:2.7.12.1];K08841|2|1e-86|322|dre:556048|testis-specific kinase 1 [EC:2.7.12.1];K08842|3|3e-85|318|dre:568213|testis-specific kinase 2 [EC:2.7.12.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process 43074 1719.00 97.18 90.49 -0.10290106288407 Down 0.252905824858011 alrm astrocytic leucine-rich repeat molecule K13023|1|1e-28|127|rno:303861|carboxypeptidase N regulatory subunit - GO:0005488//binding - 246561 751.00 3.495 4.02 0.201903045803492 Up 0.178675208030643 CG30355 CG30355 - - - - 41166 1434.98 273.595 240.145 -0.188136094052647 Down 0.412495046889447 Crc calreticulin, isoform B K08057|1|0.0|665|dme:Dmel_CG9429|calreticulin GO:0044432//endoplasmic reticulum part GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0007635//chemosensory behavior;GO:0018988;GO:0044267//cellular protein metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0007399//nervous system development;GO:0009605//response to external stimulus 42116 1103.00 1.19 9.52 3 Up 0.733489631488575 CG14329 CG14329 - - - - 35735 1737.00 1.965 14.19 2.85227337180195 Up 0.753698322546559 phr photorepair, isoform B K01669|1|0.0|1085|dme:Dmel_CG11205|deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] - GO:0003913//DNA photolyase activity;GO:0003913//DNA photolyase activity GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process 43727 1344.00 7.875 7.01 -0.167865479264018 Down 0.218234050984018 CG1792 CG1792 K09228|1|3e-27|123|cfa:485363|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 39406 2643.00 4.98 5.425 0.123477395263761 Up 0.146182802800158 CG32105 CG32105, isoform C K09371|1|1e-157|557|dpo:Dpse_GA16684|LIM homeobox transcription factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity - 39028 2132.00 24.985 20.535 -0.282977270756832 Down 0.434982168802008 Srp68 signal recognition particle protein 68 K03107|1|0.0|1118|dme:Dmel_CG5064|signal recognition particle subunit SRP68 - GO:0003723//RNA binding GO:0006613//cotranslational protein targeting to membrane;GO:0007033//vacuole organization;GO:0006914//autophagy 39165 4261.49 19.18 17.215 -0.155936539448215 Down 0.284539690925901 CalpB Calpain-B, isoform B K08585|1|0.0|1645|dme:Dmel_CG8107|calpain, invertebrate [EC:3.4.22.-] GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0004197//cysteine-type endopeptidase activity GO:0016485//protein processing 19835075 893.50 4.02 3.66 -0.135351852894886 Down 0.138026680755514 43761 1807.52 9.735 8.275 -0.234421667025715 Down 0.296295073306036 CG2003 CG2003, isoform C K08193|1|9e-53|208|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|4|4e-50|199|cin:100187364|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - GO:0006810//transport;GO:0006810//transport 36073 6895.29 10.44 12.76 0.289506617194985 Up 0.377691190067362 Hr46 hormone receptor-like in 46, isoform H K14033|1|0.0|902|dya:Dyak_GE21721|nuclear receptor subfamily 1 group F member 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0009653//anatomical structure morphogenesis 31450 2613.76 5.795 6.35 0.131947930653056 Up 0.164707436269978 CG3309 CG3309, isoform B - - - - 37883 1882.00 0.125 0.72 2.52606881166759 Up 0.311121384229296 CG13575 CG13575 K08378|1|6e-11|70.1|bfo:BRAFLDRAFT_74637|G protein-coupled receptor 103;K04233|2|5e-10|67.0|bfo:BRAFLDRAFT_217292|galanin receptor, invertebrate;K04225|3|2e-09|65.1|cqu:CpipJ_CPIJ012071|tachykinin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 31021 2125.84 192.435 209.91 0.125399677722537 Up 0.317923656056003 CG5273 CG5273, isoform C - - - - 49893 1182.04 163.775 150.245 -0.124398168303741 Down 0.29715361246863 CG17508 CG17508, isoform B - - - - 33252 4359.00 1.82 1.98 0.121561979880914 Up 0.0902126535464272 CG3544 CG3544, isoform B K00854|1|3e-139|495|dgr:Dgri_GH19552|xylulokinase [EC:2.7.1.17] - GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0044238//primary metabolic process 41901 2762.00 11.705 13.38 0.192953181529448 Up 0.291275921278563 CG5404 CG5404 K03321|1|1e-31|138|rno:64076|sulfate permease, SulP family;K04602|2|4e-28|127|gga:416011|cadherin EGF LAG seven-pass G-type receptor 3 (flamingo);K13962|3|3e-27|124|gga:428369|solute carrier family 26 (sulfate anion transporter), member 7 - - - 46386 2664.91 9.15 8.815 -0.0538111738512231 Down 0.100944393078854 CG13397 CG13397, isoform B K01205|1|0.0|1576|dme:Dmel_CG13397|alpha-N-acetylglucosaminidase [EC:3.2.1.50] - GO:0043167//ion binding GO:0044238//primary metabolic process 36790 4589.00 0.7 0.405 -0.789433014060342 Down 0.17458063663981 Ptp52F Ptp52F K01104|1|0.0|2748|dme:Dmel_CG18243|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 34546 4327.00 12.88 13.97 0.117199427294846 Up 0.209648659358077 CG6230 CG6230 K01552|1|0.0|2354|dme:Dmel_CG6230| [EC:3.6.3.-] GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0032559 GO:0009206;GO:0006811//ion transport 43720 1548.00 30.32 34.75 0.196743224327141 Up 0.3732664113063 CG1635 CG1635 K01068|1|2e-11|70.5|nve:NEMVE_v1g115538|palmitoyl-CoA hydrolase [EC:3.1.2.2];K12417|2|6e-10|65.9|nve:NEMVE_v1g114387|acyl-CoA thioesteraes 11 [EC:3.1.2.-] - - - 34484 2993.00 6.185 6.485 0.0683329792753298 Up 0.104906881521596 CG6729 CG6729 - - - GO:0000956//nuclear-transcribed mRNA catabolic process 34865 1374.60 0.61 0.62 0.023458972823989 Up 0.0413749834896315 CG15278 CG15278, isoform C - - - - 36719 1782.00 8.985 10.185 0.180855571455946 Up 0.254721965394268 CG30467 CG30467 - - - GO:0002526//acute inflammatory response 36004 1126.76 2.05 3.26 0.669248054725631 Up 0.349755646546031 CG1690 CG1690, isoform B - - - - 41500 897.00 2.615 0.92 -1.50710518018993 Down 0.462125214634791 Tim17a1 Tim17a1, isoform B K10836|1|3e-117|421|dme:Dmel_CG10090|mitochondrial protein-transporting ATPase [EC:3.6.3.51] - - - 42363 1482.00 3.41 3.22 -0.0827110509095556 Down 0.088693699643376 CG17186 CG17186 - GO:0044464//cell part GO:0046914//transition metal ion binding - 34252 1660.00 0.435 0.585 0.427421223734676 Up 0.113096024303262 CG3748 CG3748, isoform C - GO:0012505//endomembrane system - - 32764 1828.75 27.405 29.865 0.124016587093014 Up 0.258651433099987 Ucp4A Ucp4A, isoform C K03454|1|4e-54|212|tgu:100230115|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity GO:0046907//intracellular transport;GO:0006818//hydrogen transport;GO:0046907//intracellular transport;GO:0006818//hydrogen transport 36708 268.00 104.06 287.41 1.46569464665201 Up 0.767600052833179 Mtk metchnikowin - - - GO:0050832//defense response to fungus;GO:0042742//defense response to bacterium 35604 1164.06 10.335 12.68 0.29501635671396 Up 0.38403117157575 CG3358 CG3358, isoform G K03424|1|4e-178|623|dme:Dmel_CG3358|TatD DNase family protein [EC:3.1.21.-] - GO:0004520//endodeoxyribonuclease activity;GO:0004520//endodeoxyribonuclease activity - 14462666 3405.00 0.17 0.13 -0.387023123109247 Down 0.0673292827895919 10178968 224.00 0.01 0.25 4.64385618977472 Up 0.24085325584467 CG42781 CG42781 - - - - 35027 1562.00 1.345 1.775 0.40021285183542 Up 0.191256108836349 CG12288 CG12288 K13091|1|4e-11|69.7|aga:AgaP_AGAP008433|RNA-binding protein 39 GO:0015630//microtubule cytoskeleton GO:0003723//RNA binding - 19835194 776.00 0.73 0.375 -0.961005868384136 Down 0.204860652489764 36308 1948.00 28.97 25.74 -0.170547631049701 Down 0.327466649055607 Cct5 T-complex chaperonin 5, isoform B K09497|1|0.0|951|dme:Dmel_CG8439|T-complex protein 1 subunit epsilon GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process 43820 4376.00 9.3 10.205 0.133973561037325 Up 0.203209615638621 Kif3C kinesin family member 3C ortholog K10394|1|0.0|1267|dme:Dmel_CG17461|kinesin family member 3/17 - - - 32547 8597.14 15.375 18.075 0.233409236724516 Up 0.360619469026549 tay tay bridge, isoform D - - - GO:0008344//adult locomotory behavior;GO:0007632//visual behavior 3885643 699.00 14.91 15.8 0.0836443007810231 Up 0.164344208162726 CG34039 CG34039 - - - - 36023 2115.00 2.31 1.945 -0.248122696429866 Down 0.156782459384493 CG18446 CG18446 - GO:0044464//cell part GO:0046914//transition metal ion binding - 39720 2720.59 176.3 192.095 0.123787493230912 Up 0.298507462686567 fwe flower, isoform C - GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0030672//synaptic vesicle membrane GO:0005261//cation channel activity;GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0006897//endocytosis;GO:0070838//divalent metal ion transport;GO:0030182//neuron differentiation;GO:0006897//endocytosis;GO:0070838//divalent metal ion transport;GO:0030182//neuron differentiation;GO:0006897//endocytosis;GO:0070838//divalent metal ion transport;GO:0030182//neuron differentiation 14462654 499.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 38765 2067.00 26.735 21.225 -0.332965122958217 Down 0.483687755910712 G-ialpha65A G protein alpha i subunit K04630|1|0.0|706|dme:Dmel_CG10060|guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide GO:0044448//cell cortex part;GO:0019897//extrinsic to plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0051293//establishment of spindle localization;GO:0023060;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0051301//cell division;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0007166//cell surface receptor signaling pathway 43774 5206.90 30.27 33.77 0.157853504179963 Up 0.320763439439968 CG31998 CG31998, isoform B - - - - 36177 523.00 0.09 0.01 -3.16992500144231 Down 0.120756835292564 CG13218 CG13218 - - - - 31890 1664.00 6.005 4.655 -0.367383078146841 Down 0.33109893012812 BCL7-like BCL7-like - - - - 37765 531.00 0.16 0.11 -0.540568381362703 Down 0.0745938449346189 CG13561 CG13561 K12602|1|3e-09|60.8|dpo:Dpse_GA17766|WD repeat-containing protein 61 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - 38477 2582.00 16.225 18.935 0.222836942997918 Up 0.35484084004755 CG11593 CG11593, isoform C K01514|1|3e-43|177|ssc:100155100|exopolyphosphatase [EC:3.6.1.11] - - - 19835013 882.00 0.135 0.065 -1.05444778402238 Down 0.0917316074494783 8674102 1748.08 10.73 9.97 -0.105984666358326 Down 0.178113855501255 12798585 657.00 0.01 0.275 4.78135971352466 Up 0.252509576013737 CG43098 CG43098 - - - - 31897 525.32 1113.265 1014.13 -0.134554449224428 Down 0.325551446308282 RpS28b ribosomal protein S28b, isoform B K02979|1|5e-23|106|dvi:Dvir_GJ19416|small subunit ribosomal protein S28e GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 41759 1623.00 476.825 266.725 -0.838106824175021 Down 0.717837802139744 Cyp313a1 Cyp313a1 K00517|1|0.0|1004|dme:Dmel_CG3360| [EC:1.14.-.-] - - - 10178787 165.00 27.655 26.565 -0.0580136292428548 Down 0.152588825782591 CG42852 CG42852 - - - - 261610 2411.00 0.53 0.275 -0.94656074103854 Down 0.169924712719588 pgant4 polypeptide GalNAc transferase 4, isoform C K00710|1|0.0|1314|dsi:Dsim_GD23236|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process;GO:0009311//oligosaccharide metabolic process 38470 2180.95 2.72 3.11 0.193307928880263 Up 0.153579447893277 CG14985 CG14985, isoform C - - - - 40024 1575.00 1.105 1.13 0.032276403023756 Up 0.0445449742438251 CG18234 CG18234 K00472|1|4e-72|272|dvi:Dvir_GJ22993|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 35298 2011.00 0.755 1.565 1.05161410760754 Up 0.316206577730815 nesd nessun dorma, isoform B - - - - 318226 706.62 2.705 5.985 1.14572265311669 Up 0.552073702285035 CG32817 CG32817, isoform C - - - - 41100 1393.00 2.405 2.31 -0.0581440423539848 Down 0.0667679302602034 CG16734 CG16734 - - GO:0003824//catalytic activity - 42664 477.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 btn buttonless K09322|1|5e-23|106|tgu:100226490|homeobox protein MOX GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001756//somitogenesis 43482 2031.00 10.875 9.955 -0.12752217990295 Down 0.204398362171444 CG7568 CG7568, isoform E K12662|1|4e-28|125|dgr:Dgri_GH15383|U4/U6 small nuclear ribonucleoprotein PRP4 - - - 43374 3556.63 23.89 26.355 0.1416698382732 Up 0.282426363756439 Moca-cyp Moca-cyp, isoform C K09566|1|2e-155|550|dpo:Dpse_GA15038|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8];K01802|4|2e-123|443|dme:Dmel_CG1866|peptidylprolyl isomerase [EC:5.2.1.8] GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity;GO:0016859//cis-trans isomerase activity;GO:0016859//cis-trans isomerase activity GO:0044260;GO:0044238//primary metabolic process;GO:0000377;GO:0000377;GO:0044267//cellular protein metabolic process 34054 547.00 0.745 0.67 -0.153079330004389 Down 0.0705653150178312 CG7211 CG7211 K02140|1|9e-55|211|dme:Dmel_CG7211|F-type H+-transporting ATPase subunit g [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 44250 4845.00 4.055 3.585 -0.177728795515368 Down 0.166094307224937 Cpsf160 cleavage and polyadenylation specificity factor 160, isoform B K11251|1|3e-53|211|spu:759005|histone H2A;K10610|2|5e-11|71.2|aga:AgaP_AGAP002472|DNA damage-binding protein 1 GO:0005849//mRNA cleavage factor complex;GO:0005849//mRNA cleavage factor complex GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0031124//mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing 37214 633.00 234.885 202.035 -0.217349341051816 Down 0.448289525822216 FK506-bp2 FK506-binding protein 2 K09568|1|7e-59|226|dme:Dmel_CG11001|FK506-binding protein 1 [EC:5.2.1.8];K01802|5|1e-44|179|xla:447040|peptidylprolyl isomerase [EC:5.2.1.8] - - - 19835223 1103.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 37520 2412.00 17.775 16.3 -0.124977595388338 Down 0.22995641262713 CG6613 CG6613 - - GO:0046914//transition metal ion binding GO:0023033 59216 3697.34 1.805 2.57 0.509769522306707 Up 0.26958129705455 CG32165 CG32165, isoform C - - GO:0022892 GO:0015031//protein transport 32801 920.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 Him holes in muscle - - - GO:0048634 19835903 422.00 0.105 0.23 1.13124453327825 Up 0.11781798969753 41640 1508.88 105.165 130.18 0.307853178663758 Up 0.531138555012548 Dic1 dicarboxylate carrier 1, isoform C K13577|1|6e-146|517|dme:Dmel_CG8790|mitochondrial dicarboxylate carrier - - - 33279 1288.00 0.24 0.235 -0.0303736490435187 Down 0.0382380134724607 CG4415 CG4415, isoform B K03626|1|4e-30|132|phu:Phum_PHUM253160|nascent polypeptide-associated complex subunit alpha GO:0043234//protein complex;GO:0043234//protein complex - GO:0006886//intracellular protein transport;GO:0006886//intracellular protein transport 33637 943.00 0.29 0.37 0.351472370501378 Up 0.0858539162594109 CG15429 CG15429, isoform B - - GO:0005506//iron ion binding - 318859 1233.84 0.795 1.425 0.841935153767748 Up 0.266741513670585 CG31626 CG31626, isoform B K11657|1|2e-33|143|dme:Dmel_CG8677|remodeling and spacing factor 1;K11405|2|9e-06|51.2|oaa:100079804|histone deacetylase 8 [EC:3.5.1.98] GO:0044464//cell part;GO:0044464//cell part GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity - 36561 3898.00 5.31 6.28 0.242052698087473 Up 0.25138687095496 pea peanuts K12818|1|0.0|1825|dse:Dsec_GM21509|ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13] GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0000380//alternative mRNA splicing, via spliceosome 41758 883.00 7.92 7.55 -0.0690237858671682 Down 0.114614978206314 CG8461 CG8461 - - - - 44497 7214.00 2.585 2.23 -0.21312057039463 Down 0.149947166820763 Tollo tollo K06838|1|1e-44|183|mmu:20562|slit 1;K06839|5|2e-44|182|dre:80353|slit 2 GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004872//receptor activity GO:0006952//defense response;GO:0023060;GO:0010559//regulation of glycoprotein biosynthetic process;GO:0048666//neuron development 43296 1190.00 4.145 5.94 0.519090829305015 Up 0.397635715229164 CG3330 CG3330 - - - - 318981 2199.00 4.425 4.43 0.0016292435846586 Up 0.0382380134724607 CG31849 CG31849 K00737|1|0.0|946|dme:Dmel_CG31849|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.144] GO:0044464//cell part GO:0008375//acetylglucosaminyltransferase activity GO:0006486//protein glycosylation 37194 641.00 1.87 1.545 -0.275431431983262 Down 0.151466120723815 CG15116 CG15116 K00432|1|2e-102|371|dme:Dmel_CG15116|glutathione peroxidase [EC:1.11.1.9] - - - 44965 1100.57 523.705 470.44 -0.154743645673076 Down 0.356326773213578 Fer2LCH ferritin 2 light chain homologue, isoform E K00522|1|8e-12|71.2|nve:NEMVE_v1g123261|ferritin heavy chain [EC:1.16.3.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport;GO:0030005;GO:0008152//metabolic process;GO:0000041//transition metal ion transport 32994 8011.00 1.505 1.72 0.192645077942396 Up 0.113954563465857 vfl vielfaltig, isoform G K09229|1|4e-21|105|mdo:100016909|KRAB and SCAN domains-containing zinc finger protein;K09228|4|2e-20|102|cfa:484331|KRAB domain-containing zinc finger protein GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0044427//chromosomal part;GO:0031981//nuclear lumen GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0007049//cell cycle;GO:0007049//cell cycle 2768965 1856.00 37.725 44.315 0.232274212536489 Up 0.419627526086382 asparagine-synthetase asparagine synthetase K01953|1|0.0|1135|dme:Dmel_CG33486|asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] - GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0006528//asparagine metabolic process 42128 1046.00 8.795 8.455 -0.0568788230619778 Down 0.106987187954035 CG7655 CG7655 - - - - 45374 5939.63 32.07 34.255 0.0950902313366597 Up 0.226819442609959 fwd four wheel drive, isoform D K00888|1|0.0|2315|dme:Dmel_CG7004|phosphatidylinositol 4-kinase [EC:2.7.1.67] - GO:0001727//lipid kinase activity;GO:0001727//lipid kinase activity;GO:0001727//lipid kinase activity GO:0000212//meiotic spindle organization;GO:0019932//second-messenger-mediated signaling;GO:0006796//phosphate-containing compound metabolic process;GO:0048610//cellular process involved in reproduction;GO:0030384;GO:0010259//multicellular organismal aging;GO:0007283//spermatogenesis;GO:0032506;GO:0033206//cytokinesis after meiosis;GO:0000212//meiotic spindle organization;GO:0019932//second-messenger-mediated signaling;GO:0006796//phosphate-containing compound metabolic process;GO:0048610//cellular process involved in reproduction;GO:0030384;GO:0010259//multicellular organismal aging;GO:0007283//spermatogenesis;GO:0032506;GO:0033206//cytokinesis after meiosis;GO:0000212//meiotic spindle organization;GO:0019932//second-messenger-mediated signaling;GO:0006796//phosphate-containing compound metabolic process;GO:0048610//cellular process involved in reproduction;GO:0030384;GO:0010259//multicellular organismal aging;GO:0007283//spermatogenesis;GO:0032506;GO:0033206//cytokinesis after meiosis 36968 2021.00 2.075 1.55 -0.42084312096005 Down 0.215427288337076 veil veil, isoform B K01081|1|0.0|1103|dme:Dmel_CG4827|5'-nucleotidase [EC:3.1.3.5] - - - 36123 2538.00 6.025 5.23 -0.204150294870383 Down 0.220776647734777 Elp2 elongator complex protein 2 K11374|1|0.0|1638|dme:Dmel_CG11887|elongator complex protein 2 - - - 34930 2304.00 3.665 4.005 0.127989044274898 Up 0.131290450402853 Ku80 Ku80 K10885|1|0.0|1410|dme:Dmel_CG18801|ATP-dependent DNA helicase 2 subunit 2 GO:0033202;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity GO:0000726 19836235 1010.00 0.355 0.615 0.792767385834558 Up 0.163881917844406 37434 1987.00 4.085 5.095 0.318746068020131 Up 0.280379078061022 CG9754 CG9754 - - - - 40804 1358.00 0.73 1 0.454031630894707 Up 0.152753929467706 CG2336 CG2336 - - GO:0003824//catalytic activity GO:0008152//metabolic process 43033 3016.00 0.64 0.635 -0.0113153132278341 Down 0.041044776119403 Cad96Cb cadherin 96Cb, isoform D K04601|1|1e-29|132|bfo:BRAFLDRAFT_130073|cadherin EGF LAG seven-pass G-type receptor 2 (flamingo) GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//cell-cell adhesion;GO:0060541//respiratory system development;GO:0016337//cell-cell adhesion;GO:0060541//respiratory system development 41638 2682.77 0.825 1.465 0.828434640176432 Up 0.267963280940431 CG8795 pyrokinin 2 receptor 2, isoform B K05052|1|3e-48|193|dre:557276|neuromedin U receptor 1;K05053|2|6e-48|192|mmu:216749|neuromedin U receptor 2 - - - 41232 661.00 1.145 1.615 0.496186566596981 Up 0.209021265354643 Npc2d Niemann-Pick type C-2d K13443|1|7e-19|93.6|aga:AgaP_AGAP002851|Niemann-Pick C2 protein - - - 43491 4301.00 0.815 0.78 -0.063325935368829 Down 0.0489697530048871 CAP-D2 CAP-D2 condensin subunit K06677|1|0.0|2530|dme:Dmel_CG1911|condensin complex subunit 1 GO:0000793//condensed chromosome;GO:0043231//intracellular membrane-bounded organelle - GO:0000070//mitotic sister chromatid segregation 32539 2135.00 12.815 11.245 -0.188549817513761 Down 0.285497292299564 Aats-arg Arginyl-tRNA synthetase K01887|1|0.0|1216|dme:Dmel_CG9020|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 41384 1969.00 12.78 11.72 -0.124915266524747 Down 0.207436269977546 CG10898 CG10898 K03574|1|6e-21|102|cbr:CBG08712|7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] - GO:0003824//catalytic activity - 19835038 293.00 0.01 0.175 4.12928301694497 Up 0.187062475234447 3772172 413.00 0.6 0.01 -5.90689059560852 Down 0.395357284374587 His4:CG33885 histone H4 K11254|1|8e-40|162|smm:Smp_053290|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 35009 1648.77 60.75 45.32 -0.42273654755999 Down 0.581065909391098 CG17928 CG17928, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005506//iron ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0006631//fatty acid metabolic process 36817 3684.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG9068 CG9068 K10408|1|0.0|1071|dme:Dmel_CG17866|dynein heavy chain, axonemal - GO:0017111//nucleoside-triphosphatase activity - 41466 1696.45 0.45 0.45 0 - 0.0382380134724607 CG14736 CG14736, isoform G K03364|1|6e-08|59.7|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part - - 36780 1989.16 10.62 17.6 0.728791662720506 Up 0.605237088891824 Jhe juvenile hormone esterase, isoform C K01063|1|0.0|1115|dme:Dmel_CG8425|juvenile-hormone esterase [EC:3.1.1.59];K01044|2|2e-96|353|dme:Dmel_CG8424|carboxylesterase [EC:3.1.1.1];K03927|4|2e-63|243|api:100168834|carboxylesterase type B [EC:3.1.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004091//carboxylesterase activity;GO:0005488//binding;GO:0004091//carboxylesterase activity GO:0006716;GO:0006716 10178822 818.00 0.15 0.485 1.69302224657861 Up 0.218531237617224 CG42697 CG42697 - - - - 39399 4619.60 32.02 39.15 0.290038999662146 Up 0.474012679963017 app approximated, isoform T - GO:0044448//cell cortex part;GO:0044448//cell cortex part;GO:0044448//cell cortex part;GO:0044448//cell cortex part;GO:0044448//cell cortex part;GO:0044448//cell cortex part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007478//leg disc morphogenesis;GO:0008283//cell proliferation;GO:0001736//establishment of planar polarity;GO:0007478//leg disc morphogenesis;GO:0008283//cell proliferation;GO:0001736//establishment of planar polarity;GO:0007478//leg disc morphogenesis;GO:0008283//cell proliferation;GO:0001736//establishment of planar polarity;GO:0007478//leg disc morphogenesis;GO:0008283//cell proliferation;GO:0001736//establishment of planar polarity;GO:0007478//leg disc morphogenesis;GO:0008283//cell proliferation;GO:0001736//establishment of planar polarity;GO:0007478//leg disc morphogenesis;GO:0008283//cell proliferation;GO:0001736//establishment of planar polarity 12798228 1525.00 0.255 0.255 0 - 0.0382380134724607 37873 1871.45 15.835 11.13 -0.508663274686231 Down 0.527704398362171 Nop60B nucleolar protein at 60B, isoform G K11131|1|0.0|800|dme:Dmel_CG3333|H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0016836//hydro-lyase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0016836//hydro-lyase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0016836//hydro-lyase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0016836//hydro-lyase activity GO:0009451//RNA modification;GO:0042254//ribosome biogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0042254//ribosome biogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0042254//ribosome biogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0042254//ribosome biogenesis;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression 33190 1730.65 7.67 7.835 0.0307066969696467 Up 0.0722493726059966 CG3645 CG3645, isoform C K05542|1|0.0|966|dme:Dmel_CG3645|tRNA-dihydrouridine synthase 1 [EC:1.-.-.-] - GO:0030554//adenyl nucleotide binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0030554//adenyl nucleotide binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process 38604 567.00 0.145 0.255 0.814444346843923 Up 0.106789063531898 CG4597 CG4597 - - - - 38491 4462.57 58.585 63.57 0.117814761595407 Up 0.280973451327434 ens ensconsin, isoform L - - - GO:0032886//regulation of microtubule-based process;GO:0032886//regulation of microtubule-based process;GO:0032886//regulation of microtubule-based process;GO:0032886//regulation of microtubule-based process;GO:0032886//regulation of microtubule-based process;GO:0032886//regulation of microtubule-based process 44127 2082.00 8.935 7.865 -0.184020963625804 Down 0.242735437854973 mab-21 mab-21 - GO:0043231//intracellular membrane-bounded organelle - - 246492 494.00 10.13 9.145 -0.147579099052422 Down 0.22011623299432 Cpr60D cuticular protein 60D, isoform B - - GO:0005198//structural molecule activity - 38522 4187.00 0.345 0.16 -1.10852445677817 Down 0.144531765949016 CG1273 CG1273 - - - - 39250 1891.00 18.68 19.04 0.0275390235982815 Up 0.0906419231277242 CG7638 CG7638 - - - - 39419 2724.24 2.11 2.52 0.256180734792732 Up 0.16774534407608 eyg eyegone, isoform C K08031|1|7e-43|176|xtr:448447|paired box protein 6 - GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0035220//wing disc development;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0048592//eye morphogenesis;GO:0007431//salivary gland development;GO:0006350;GO:0035220//wing disc development;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0048592//eye morphogenesis;GO:0007431//salivary gland development;GO:0006350 35579 1290.00 0.035 0.04 0.192645077942396 Up 0.0382380134724607 ZIP1 Zinc/iron regulated transporter-related protein 42C.1 - GO:0044464//cell part GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport 34761 2973.03 1.37 1.09 -0.3298477581836 Down 0.148329150706644 Tehao tehao, isoform B K05401|1|2e-29|132|spu:587154|toll-like recepto 3;K10160|5|2e-29|132|dre:795671|toll-like receptor 4 GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004872//receptor activity GO:0023060;GO:0002118//aggressive behavior;GO:0002783;GO:0007166//cell surface receptor signaling pathway 35704 1200.43 10.655 10.35 -0.041899825396016 Down 0.0944723286223749 CG30491 CG30491, isoform B K00100|1|2e-104|379|dme:Dmel_CG2070| [EC:1.1.1.-];K11161|2|2e-81|303|bta:508082|retinol dehydrogenase 13 [EC:1.1.1.-];K11153|4|3e-80|298|gga:423274|retinol dehydrogenase 12 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 2768853 2300.00 0.43 0.32 -0.426264754702098 Down 0.0990622110685511 mei-W68 meiotic W68 K10878|1|1e-177|623|dme:Dmel_CG7753|meiotic recombination protein SPO11 GO:0043232 GO:0003916//DNA topoisomerase activity;GO:0032559 GO:0007146 43973 1572.00 0.225 0.22 -0.0324214776923775 Down 0.0416391493858143 Lip1 lipase 1, isoform B K01066|1|0.0|832|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01046|2|4e-84|312|dpo:Dpse_GA20265|triacylglycerol lipase [EC:3.1.1.3] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 43410 2185.00 13.145 7.575 -0.795196348257733 Down 0.591137234183067 CG14528 CG14528 K01415|1|2e-128|460|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|5e-61|236|tgu:100227361|membrane metallo-endopeptidase-like 1;K01389|3|3e-60|233|tgu:100224600|neprilysin [EC:3.4.24.11] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 8674107 855.00 0.28 0.33 0.237039197300849 Up 0.0670981376304319 CG42590 CG42590 - - - - 19836092 382.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 19836154 755.00 220.2 149.465 -0.559006778713423 Down 0.661108175934487 14462481 535.00 2.55 2.385 -0.0965079808533464 Down 0.0880002641658962 32502 1586.00 0.03 0.085 1.50250034052918 Up 0.0866464139479593 CG12708 CG12708, isoform B - - - - 35944 1905.31 147.045 128.98 -0.189110354158371 Down 0.406022982432968 VhaAC45 vacuolar H[+] ATPase AC45 accessory subunit, isoform B K03662|1|0.0|686|dme:Dmel_CG8029|V-type H+-transporting ATPase S1 subunit [EC:3.6.3.14] GO:0033176;GO:0033176 GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process 31356 1320.00 0.09 0.035 -1.36257007938471 Down 0.0864152687887994 CG15375 CG15375 - - - - 42821 2506.45 49.94 58.37 0.225031246954027 Up 0.430194161933694 Pli pellino, isoform B K11964|1|0.0|884|dya:Dyak_GE23916|pellino - - GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0002376//immune system process;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0002376//immune system process;GO:0023060 14462707 1157.00 0.01 0.08 3 Up 0.110718531237617 261631 759.00 15.145 9.48 -0.675882613897113 Down 0.576476026944921 Rpb7 Rpb7 K03015|1|3e-97|353|dsi:Dsim_GD20374|DNA-directed RNA polymerase II subunit G GO:0016591//DNA-directed RNA polymerase II, holoenzyme GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0016301//kinase activity GO:0012501//programmed cell death;GO:0006396//RNA processing;GO:0006354//DNA-dependent transcription, elongation;GO:0006352//DNA-dependent transcription, initiation 2768832 600.00 0.41 0.72 0.812372996824228 Up 0.182472592788271 CG33469 CG33469, isoform B - - - - 40144 2850.08 11.055 11.99 0.117132633597998 Up 0.198256505085193 CG8786 CG8786, isoform G K13346|1|1e-06|55.8|tad:TRIADDRAFT_57553|peroxin-10 - GO:0046914//transition metal ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 246443 843.00 0.52 0.175 -1.57115670119613 Down 0.215262184651961 CG30082 CG30082 K01312|1|2e-29|129|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01320|2|3e-28|125|xla:444394|coagulation factor VII [EC:3.4.21.21];K01362|3|8e-28|124|dpo:Dpse_GA18526| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39320 1529.00 25.49 23.97 -0.0887014643730689 Down 0.198817857614582 Ccdc56 Coiled-coil domain containing 56 K02528|1|3e-14|80.1|mmu:66254|dimethyladenosine transferase [EC:2.1.1.-] GO:0031980 GO:0008173//RNA methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0008134//transcription factor binding GO:0006412//translation;GO:0006364//rRNA processing;GO:0006351//transcription, DNA-dependent 3772102 944.50 1.72 1.68 -0.0339473319233377 Down 0.0499603751155726 40598 1053.00 3.795 2.09 -0.860596943334584 Down 0.424613657376833 Hus1-like Hus1-like, isoform B K10903|1|2e-142|505|dme:Dmel_CG2525|HUS1 checkpoint protein - - GO:0048523//negative regulation of cellular process;GO:0006259//DNA metabolic process;GO:0051320//S phase;GO:0006997//nucleus organization;GO:0006974//response to DNA damage stimulus 19834817 732.00 8.59 9.155 0.0919017546588737 Up 0.147668735966187 43612 2203.00 0.105 0.155 0.561878887608115 Up 0.0745938449346189 CG15533 CG15533 K12350|1|1e-86|321|phu:Phum_PHUM427830|sphingomyelin phosphodiesterase [EC:3.1.4.12] - GO:0004620//phospholipase activity GO:0006684//sphingomyelin metabolic process 37527 401.00 0.215 0.125 -0.782408564927373 Down 0.0974772156914542 CG11269 CG11269 - - - - 38959 2284.00 13.035 12.205 -0.0949182877544026 Down 0.169396380927222 exo70 Exo70 ortholog K07195|1|0.0|1338|dme:Dmel_CG7127|exocyst complex component 7 GO:0043234//protein complex - GO:0016192//vesicle-mediated transport 19836205 1586.00 4.625 4.9 0.0833283835988962 Up 0.104807819310527 38994 1391.00 0.815 1 0.295128035543647 Up 0.115902786950205 Pex7 peroxin 7, isoform B K13341|1|0.0|699|dme:Dmel_CG6486|peroxin-7 - GO:0000268//peroxisome targeting sequence binding;GO:0000268//peroxisome targeting sequence binding GO:0006909//phagocytosis;GO:0006996//organelle organization;GO:0006909//phagocytosis;GO:0006996//organelle organization 37041 711.00 0.345 0.995 1.52810016376548 Up 0.301182142385418 CG14490 CG14490 K04575|1|8e-18|89.7|tca:100142202|amyotrophic lateral sclerosis 2 (juvenile) - - - 33777 1604.00 34.255 31.23 -0.133382015757734 Down 0.281237617223616 CG7277 CG7277 K06126|1|0.0|909|dme:Dmel_CG7277|ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] - GO:0030554//adenyl nucleotide binding;GO:0004497//monooxygenase activity GO:0006743//ubiquinone metabolic process 33606 2418.00 3.575 3.425 -0.0618392538178629 Down 0.0767401928411042 CG3407 CG3407 K09228|1|2e-41|171|api:100159445|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 318865 1347.91 8.26 9.255 0.164091208451129 Up 0.225828820499274 CG31636 CG31636, isoform B K10693|1|9e-14|78.2|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0044464//cell part - GO:0051234//establishment of localization 36997 832.00 6.205 6.52 0.0714407541007209 Up 0.106557918372738 icln icln K05019|1|6e-89|327|dpo:Dpse_GA18528|chloride channel, nucleotide-sensitive, 1A - - - 40739 3293.06 195.44 178.105 -0.133997750459351 Down 0.317923656056003 Rm62 Rm62, isoform M K12823|1|0.0|890|dse:Dsec_GM10578|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0005700//polytene chromosome GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006959//humoral immune response;GO:0035194//posttranscriptional gene silencing by RNA 19835031 261.00 0.18 0.6 1.73696559416621 Up 0.245575221238938 36529 2883.08 419.255 482.33 0.202192556399929 Up 0.429137498348963 CG6329 CG6329, isoform F - - - - 31047 2285.24 0.255 0.455 0.835369298227201 Up 0.143805309734513 CG3690 CG3690, isoform B K06258|1|4e-51|202|nvi:100122803|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 - - - 38890 5516.52 21.61 24.585 0.186079282961108 Up 0.340873068286884 nmo nemo, isoform H K04468|1|0.0|765|dwi:Dwil_GK20588|nemo like kinase [EC:2.7.11.24] - GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0001654//eye development;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0009629//response to gravity;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0009629//response to gravity;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0009629//response to gravity;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0009629//response to gravity;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0009629//response to gravity;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0003002//regionalization;GO:0016055//Wnt receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0009629//response to gravity;GO:0006464//cellular protein modification process 32983 1903.57 16.115 20.68 0.359831997255389 Up 0.480088495575221 CG14232 CG14232, isoform B - - GO:0005504//fatty acid binding - 33101 1173.00 0.56 0.55 -0.0259952085329446 Down 0.0416391493858143 CG1722 CG1722 - - - - 317946 489.00 81.04 69.36 -0.224530275579303 Down 0.43095363888522 CG32267 CG32267 - - - - 43791 5357.00 27.73 30.185 0.122384184773246 Up 0.258651433099987 lgs legless - - - - 37388 711.00 3.97 5.515 0.474221878448425 Up 0.36689340906089 CG15653 CG15653 - - - - 40667 2062.98 1.245 2.15 0.788190917521379 Up 0.315215955620129 mia meiosis I arrest, isoform C K03131|1|0.0|1107|dme:Dmel_CG10390|transcription initiation factor TFIID subunit D5 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0045449;GO:0007281//germ cell development;GO:0007140//male meiosis;GO:0006352//DNA-dependent transcription, initiation;GO:0045449;GO:0007281//germ cell development;GO:0007140//male meiosis 37203 4903.91 26.83 33.265 0.310157979121616 Up 0.482003698322547 hppy happyhour, isoform E K08286|1|0.0|1089|dme:Dmel_CG7097|protein-serine/threonine kinase [EC:2.7.11.-];K04406|5|9e-133|475|mcc:713952|mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1] - - - 34029 1904.62 1.765 2.165 0.294698841455545 Up 0.172104081363096 CG6441 CG6441, isoform C - - - - 7354440 1459.00 0.04 0.01 -2 Down 0.0694426099590543 41448 1658.00 51.545 58.355 0.179023785706992 Up 0.37036058644829 CG18347 glutamate carrier 1, isoform B K04257|1|2e-21|103|cfa:485348|olfactory receptor;K03454|2|8e-21|101|nve:NEMVE_v1g237474|mitochondrial carrier protein, MC family;K05863|4|3e-18|93.2|ecb:100071908|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport 19835718 1547.00 0.77 0.945 0.295455883526171 Up 0.115902786950205 33651 3335.00 4.245 3.63 -0.225795005557288 Down 0.201591599524501 CG15439 CG15439 K11347|1|6e-27|123|dre:327437|protein Jade-1 - GO:0046914//transition metal ion binding - 31525 3085.43 14.1 15.31 0.118779120213632 Up 0.217177387399287 CG3726 CG3726, isoform B K09237|1|1e-29|132|der:Dere_GG11824|Cys2His2 zinc finger developmental/cell cycle regulator, other - - - 36273 1878.00 10.295 9.02 -0.190744491376873 Down 0.266114119667151 CG13189 Zinc/iron regulated transporter-related protein 48C - GO:0044464//cell part GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport 31148 794.94 66.835 49.325 -0.43828475688142 Down 0.593943996830009 CG14806 CG14806, isoform B - - - - 41070 1097.14 18.055 13.05 -0.468348613491393 Down 0.525624091929732 CAHbeta carbonic anhydrase beta, isoform B K01672|1|4e-149|527|dme:Dmel_CG11967|carbonic anhydrase [EC:4.2.1.1];K01743|1|4e-149|527|dme:Dmel_CG11967| [EC:4.2.-.-];K01673|2|2e-36|152|tad:TRIADDRAFT_29634|carbonic anhydrase [EC:4.2.1.1] - GO:0016836//hydro-lyase activity;GO:0046914//transition metal ion binding - 35937 1918.00 2.675 3.27 0.289751744209573 Up 0.209945845991283 Rad51C Rad51C K10871|1|2e-17|90.1|bta:529507|RAD51-like protein 3 - GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0044260 34286 2045.00 14.92 12.62 -0.241535625272689 Down 0.350482102760534 pelo pelota K06965|1|0.0|697|dme:Dmel_CG3959| GO:0043231//intracellular membrane-bounded organelle - GO:0042078//germ-line stem cell division;GO:0000087//M phase of mitotic cell cycle;GO:0048592//eye morphogenesis;GO:0007127//meiosis I;GO:0019827//stem cell maintenance;GO:0048232//male gamete generation;GO:0010467//gene expression;GO:0007053//spindle assembly involved in male meiosis 42199 816.00 65.535 53.965 -0.280241582512504 Down 0.486362435609563 Dlc90F dynein light chain 90F K10420|1|5e-61|234|dgr:Dgri_GH18339|dynein light chain Tctex-type 1 - - - 38747 10443.48 9.19 11.46 0.31847027746787 Up 0.388852199181086 dikar dikar, isoform G K11728|1|2e-15|86.7|aag:AaeL_AAEL015015|nucleosome-remodeling factor subunit BPTF;K06062|2|4e-14|82.8|nve:NEMVE_v1g96946|histone acetyltransferase [EC:2.3.1.48] - - GO:0008306//associative learning;GO:0008306//associative learning;GO:0008306//associative learning;GO:0008306//associative learning 40443 2882.92 238.565 224.07 -0.0904328959355035 Down 0.241975960903447 CG7470 CG7470, isoform B K12657|1|0.0|1516|dme:Dmel_CG7470|delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41] GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016774//phosphotransferase activity, carboxyl group as acceptor GO:0006560//proline metabolic process 318095 1671.57 86.735 88.82 0.0342702925393052 Up 0.111874257033417 CG32576 CG32576, isoform B K00417|1|3e-44|171|dya:Dyak_GE17257|ubiquinol-cytochrome c reductase subunit 7 [EC:1.10.2.2] - GO:0015078//hydrogen ion transmembrane transporter activity GO:0006810//transport;GO:0006810//transport;GO:0022904//respiratory electron transport chain 40165 2545.37 44.725 39.14 -0.192437726312467 Down 0.37465328226126 trc tricornered, isoform B K08790|1|0.0|932|dsi:Dsim_GD12245|serine/threonine kinase 38 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0023014//signal transduction by phosphorylation;GO:0007423//sensory organ development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010975//regulation of neuron projection development;GO:0006464//cellular protein modification process 42552 1217.00 0.45 0.55 0.289506617194985 Up 0.0890569277506274 CG15497 CG15497 - - - - 46326 2653.00 1.965 2.19 0.156401557342567 Up 0.110553427552503 l(2)dtl lethal-(2)-denticleless K11790|1|0.0|1409|dme:Dmel_CG11295|denticleless - - - 19836050 629.00 0.385 0.29 -0.408805545567329 Down 0.0941421212521464 - CG44623 - - - - 38071 1422.00 0.645 1.605 1.31520223169905 Up 0.35484084004755 Ppm1 Ppm1 K01090|1|3e-124|445|dpo:Dpse_GA14642|protein phosphatase [EC:3.1.3.16] GO:0043234//protein complex GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0006464//cellular protein modification process 246436 587.00 0.01 0.08 3 Up 0.110718531237617 Obp50d Odorant-binding protein 50d - - - - 41066 2869.00 0.02 0.01 -1 Down 0.0497292299564126 osk oskar, isoform C - GO:0005737//cytoplasm;GO:0043232;GO:0005737//cytoplasm;GO:0043232 GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0007017//microtubule-based process;GO:0007613//memory;GO:0007632//visual behavior;GO:0006996//organelle organization;GO:0006417//regulation of translation;GO:0001709//cell fate determination;GO:0051237//maintenance of RNA location;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0007316//pole plasm RNA localization;GO:0016071//mRNA metabolic process;GO:0007017//microtubule-based process;GO:0007613//memory;GO:0007632//visual behavior;GO:0006996//organelle organization;GO:0006417//regulation of translation;GO:0001709//cell fate determination;GO:0051237//maintenance of RNA location;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0007316//pole plasm RNA localization;GO:0016071//mRNA metabolic process 32035 833.80 148.21 123.93 -0.258117326175242 Down 0.484909523180557 CG1552 CG1552, isoform C - - - - 34487 1727.93 24.625 22.7 -0.117431427052824 Down 0.245806366398098 UbcD2 ubiquitin conjugating enzyme 2, isoform D K06689|1|1e-97|356|dme:Dmel_CG6720|ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0010876//lipid localization;GO:0060255;GO:0006464//cellular protein modification process;GO:0010876//lipid localization 39056 2400.00 5.41 4.435 -0.286694489525751 Down 0.266840575881654 CG4476 CG4476 K05336|1|0.0|745|dme:Dmel_CG1698|solute carrier family 6 (neurotransmitter transporter), invertebrate GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport;GO:0007610//behavior 35939 7769.09 10.025 9.71 -0.04605903592309 Down 0.098864086646414 Rme-8 receptor mediated endocytosis 8, isoform B K09533|1|0.0|4613|dme:Dmel_CG8014|DnaJ homolog subfamily C member 13 - GO:0005515//protein binding - 31579 2510.46 459.215 511.88 0.156635871337759 Up 0.371450270770044 kdn knockdown, isoform B K01647|1|0.0|987|dya:Dyak_GE16750|citrate synthase [EC:2.3.3.1] - - - 42336 1666.00 0.12 0.105 -0.192645077942396 Down 0.0514463082816008 CG17751 CG17751 K08202|1|2e-46|186|dse:Dsec_GM26581|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 34665 3553.96 181.27 206.245 0.18621896422863 Up 0.409853387927619 bun bunched, isoform P - GO:0044424//intracellular part;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0042802//identical protein binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0005975//carbohydrate metabolic process;GO:0006950//response to stress;GO:0007399//nervous system development;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0043066//negative regulation of apoptotic process;GO:0008593//regulation of Notch signaling pathway;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0048102//autophagic cell death;GO:0003002//regionalization;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0016049//cell growth;GO:0030703//eggshell formation;GO:0016477//cell migration;GO:0008593//regulation of Notch signaling pathway 43221 984.00 0.09 0.06 -0.584962500721157 Down 0.0622440892880729 CG14247 CG14247 - - - - 31162 12137.26 1.285 0.87 -0.56268105334515 Down 0.199709417514199 Hr4 Hr4, isoform K K09185|1|2e-145|518|dme:Dmel_CG16902|nuclear receptor subfamily 6 group A - - - 50101 1027.00 0.3 0.295 -0.0242475462466774 Down 0.0413749834896315 CG18672 CG18672, isoform D K01672|1|1e-122|438|dme:Dmel_CG18672|carbonic anhydrase [EC:4.2.1.1];K01743|1|1e-122|438|dme:Dmel_CG18672| [EC:4.2.-.-] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 39646 2188.00 5.84 5.3 -0.139976009429456 Down 0.166919825650509 CG13458 CG13458 - - GO:0046914//transition metal ion binding - 14462769 505.00 0.01 0.185 4.20945336562895 Up 0.199412230880993 3346235 2875.13 17.805 21.055 0.241880439806031 Up 0.381851802932241 scaf6 scaf6, isoform E K12841|1|1e-63|244|dme:Dmel_CG33522|calcium homeostasis endoplasmic reticulum protein GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000377;GO:0000377;GO:0000377 37662 1318.00 13.06 12.15 -0.104198583053287 Down 0.182274468366134 Fib fibrillarin - GO:0044452;GO:0016604//nuclear body;GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding;GO:0016741 GO:0006399//tRNA metabolic process;GO:0042254//ribosome biogenesis;GO:0010467//gene expression 42311 974.00 1.91 2.39 0.323437979945 Up 0.195185576542068 CG5217 CG5217 - - - - 42259 841.66 33.035 23.31 -0.503046340248408 Down 0.587108704266279 CG14298 CG14298, isoform B K04520|1|2e-07|55.5|gga:374198|amyloid beta (A4) protein GO:0042995//cell projection;GO:0005737//cytoplasm;GO:0043229//intracellular organelle GO:0004866//endopeptidase inhibitor activity;GO:0005488//binding GO:0044238//primary metabolic process;GO:0031175//neuron projection development;GO:0044260;GO:0050794//regulation of cellular process;GO:0065008;GO:0007610//behavior 37940 2856.34 11.91 15.65 0.393989243955867 Up 0.471338000264166 CG13594 CG13594, isoform B - - - - 43216 2101.00 0.37 0.795 1.10342958965541 Up 0.227942147668736 CG6425 CG6425 - - - - 37379 6999.91 11.82 12.855 0.121099574656124 Up 0.205917316074495 CG10543 CG10543, isoform F K09228|1|1e-37|159|bta:532421|KRAB domain-containing zinc finger protein - - - 5740204 5621.00 0.215 0.235 0.128324096975539 Up 0.0491348566900013 clos closca - - - - 33797 585.00 0.215 0.235 0.12832409697554 Up 0.0491348566900013 CG12511 CG12511, isoform D - - - - 40749 2003.00 0.085 0.045 -0.917537839808027 Down 0.0698718795403513 CG31559 CG31559 - - GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis 33925 1327.00 0.33 0.2 -0.722466024471091 Down 0.11306300356624 CG11320 CG11320 K06774|1|4e-30|132|mdo:100017555|neurotrimin - - GO:0009987//cellular process 36430 1110.45 1.49 0.905 -0.719322633378956 Down 0.24838198388588 CG13321 CG13321, isoform B - - - - 35920 1487.00 8.12 8.64 0.0895515849782924 Up 0.142616563201691 CG8078 CG8078 - GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0032559 GO:0002097 35503 1316.00 82.04 84.45 0.0417699312088961 Up 0.132908466516973 CG8245 CG8245 - - - - 35540 6547.56 14.075 17.3 0.297637115556495 Up 0.419528463875314 EcR ecdysone receptor, isoform G K14034|1|0.0|1171|dme:Dmel_CG1765|ecdysone receptor GO:0043005//neuron projection;GO:0008230//ecdysone receptor holocomplex;GO:0005694//chromosome;GO:0043005//neuron projection;GO:0008230//ecdysone receptor holocomplex;GO:0005694//chromosome;GO:0043005//neuron projection;GO:0008230//ecdysone receptor holocomplex;GO:0005694//chromosome;GO:0043005//neuron projection;GO:0008230//ecdysone receptor holocomplex;GO:0005694//chromosome;GO:0043005//neuron projection;GO:0008230//ecdysone receptor holocomplex;GO:0005694//chromosome;GO:0043005//neuron projection;GO:0008230//ecdysone receptor holocomplex;GO:0005694//chromosome GO:0008289//lipid binding;GO:0030528//transcription regulator activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding;GO:0030528//transcription regulator activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding;GO:0030528//transcription regulator activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding;GO:0030528//transcription regulator activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding;GO:0030528//transcription regulator activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding;GO:0030528//transcription regulator activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity GO:0007472//wing disc morphogenesis;GO:0006915//apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0044248//cellular catabolic process;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0014706//striated muscle tissue development;GO:0008345//larval locomotory behavior;GO:0010259//multicellular organismal aging;GO:0007613//memory;GO:0040003//chitin-based cuticle development;GO:0050793//regulation of developmental process;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0048812//neuron projection morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007281//germ cell development;GO:0007297//ovarian follicle cell migration;GO:0007591//molting cycle, chitin-based cuticle;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0014073;GO:0035051//cardiocyte differentiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0007472//wing disc morphogenesis;GO:0006915//apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0044248//cellular catabolic process;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0014706//striated muscle tissue development;GO:0008345//larval locomotory behavior;GO:0010259//multicellular organismal aging;GO:0007613//memory;GO:0040003//chitin-based cuticle development;GO:0050793//regulation of developmental process;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0048812//neuron projection morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007281//germ cell development;GO:0007297//ovarian follicle cell migration;GO:0007591//molting cycle, chitin-based cuticle;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0014073;GO:0035051//cardiocyte differentiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0007472//wing disc morphogenesis;GO:0006915//apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0044248//cellular catabolic process;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0014706//striated muscle tissue development;GO:0008345//larval locomotory behavior;GO:0010259//multicellular organismal aging;GO:0007613//memory;GO:0040003//chitin-based cuticle development;GO:0050793//regulation of developmental process;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0048812//neuron projection morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007281//germ cell development;GO:0007297//ovarian follicle cell migration;GO:0007591//molting cycle, chitin-based cuticle;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0014073;GO:0035051//cardiocyte differentiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0007472//wing disc morphogenesis;GO:0006915//apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0044248//cellular catabolic process;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0014706//striated muscle tissue development;GO:0008345//larval locomotory behavior;GO:0010259//multicellular organismal aging;GO:0007613//memory;GO:0040003//chitin-based cuticle development;GO:0050793//regulation of developmental process;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0048812//neuron projection morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007281//germ cell development;GO:0007297//ovarian follicle cell migration;GO:0007591//molting cycle, chitin-based cuticle;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0014073;GO:0035051//cardiocyte differentiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0007472//wing disc morphogenesis;GO:0006915//apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0044248//cellular catabolic process;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0014706//striated muscle tissue development;GO:0008345//larval locomotory behavior;GO:0010259//multicellular organismal aging;GO:0007613//memory;GO:0040003//chitin-based cuticle development;GO:0050793//regulation of developmental process;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0048812//neuron projection morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007281//germ cell development;GO:0007297//ovarian follicle cell migration;GO:0007591//molting cycle, chitin-based cuticle;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0014073;GO:0035051//cardiocyte differentiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0007472//wing disc morphogenesis;GO:0006915//apoptotic process;GO:0035071//salivary gland cell autophagic cell death;GO:0044248//cellular catabolic process;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0014706//striated muscle tissue development;GO:0008345//larval locomotory behavior;GO:0010259//multicellular organismal aging;GO:0007613//memory;GO:0040003//chitin-based cuticle development;GO:0050793//regulation of developmental process;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0048812//neuron projection morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007281//germ cell development;GO:0007297//ovarian follicle cell migration;GO:0007591//molting cycle, chitin-based cuticle;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0014073;GO:0035051//cardiocyte differentiation;GO:0006355//regulation of transcription, DNA-dependent 43559 665.25 34.74 34.575 -0.00686850267253587 Down 0.0592722229560164 CG7911 CG7911, isoform B K11278|1|2e-64|245|dpo:Dpse_GA20679|nucleophosmin 3;K11276|5|6e-06|51.2|nve:NEMVE_v1g241784|nucleophosmin 1 GO:0005634//nucleus GO:0005488//binding - 39627 1137.00 20.395 30.495 0.580357208773366 Up 0.609826971338 mRpL39 mitochondrial ribosomal protein L39 K01868|1|2e-18|93.6|tad:TRIADDRAFT_22327|threonyl-tRNA synthetase [EC:6.1.1.3] GO:0030529//ribonucleoprotein complex GO:0005488//binding - 36787 1449.00 3.305 2.77 -0.254764295458503 Down 0.191091005151235 CG10734 CG10734 - - - - 36224 612.00 125.675 108.065 -0.217798349148304 Down 0.439869237881389 CG12384 CG12384 - - - - 36054 2156.18 17.745 20.79 0.228477183797425 Up 0.370756835292564 egr eiger, isoform B K05480|1|5e-07|56.6|tgu:100220755|ectodysplasin-A GO:0044464//cell part;GO:0044464//cell part GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0012502//induction of programmed cell death;GO:0042742//defense response to bacterium;GO:0000165//MAPK cascade;GO:0008105//asymmetric protein localization;GO:0002376//immune system process;GO:0006582//melanin metabolic process;GO:0012502//induction of programmed cell death;GO:0042742//defense response to bacterium;GO:0000165//MAPK cascade;GO:0008105//asymmetric protein localization;GO:0002376//immune system process;GO:0006582//melanin metabolic process 42196 2901.00 3.935 3.81 -0.0465726380141643 Down 0.0696737551182142 CG8064 CG8064 K12602|1|4e-20|100|dre:393827|WD repeat-containing protein 61;K12816|5|1e-18|95.9|dre:494534|pre-mRNA-processing factor 17 - - - 41311 1337.00 72.67 59.825 -0.280611414558421 Down 0.489499405626734 Fdh formaldehyde dehydrogenase K00121|1|0.0|734|dme:Dmel_CG6598|S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006067//ethanol metabolic process 35232 1212.22 5.375 5.18 -0.0533126567902688 Down 0.0838726720380399 CG18094 CG18094, isoform B K13355|1|2e-63|243|dpe:Dper_GL21100|nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-] - GO:0003824//catalytic activity - 3355102 986.75 1071.635 547.49 -0.96890908703071 Down 0.733951921806895 Scp1 sarcoplasmic calcium-binding protein 1, isoform B - GO:0031224//intrinsic to membrane;GO:0005783//endoplasmic reticulum GO:0046872//metal ion binding;GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 49505 1610.24 10.945 9.62 -0.186163155410904 Down 0.269548276317527 fs(2)ltoPP43 female sterile (2) ltoPP43, isoform C - - - - 31277 860.00 0.075 0.105 0.485426827170242 Up 0.0618808611808216 CG3526 CG3526, isoform C - - - - 12797951 814.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 36027 5561.09 4.37 4.825 0.142895662654844 Up 0.153018095363889 CG30007 CG30007, isoform E - - - - 38540 2250.60 57.895 14.785 -1.96930451431266 Down 0.770406815480121 slow slowdown, isoform B K06824|1|3e-16|87.4|ptr:461420|nephronectin - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 59176 1246.29 193.325 235.15 0.282553119148149 Up 0.511722361643112 CG18815 CG18815, isoform E K06130|1|4e-123|441|dme:Dmel_CG18815|lysophospholipase II [EC:3.1.1.5] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - 39615 923.00 0.01 0.575 5.84549005094437 Up 0.385946374323075 gnu giant nuclei - GO:0043231//intracellular membrane-bounded organelle - GO:0001775//cell activation;GO:0006260//DNA replication;GO:0000087//M phase of mitotic cell cycle 2768924 1857.00 0.08 0.38 2.24792751344359 Up 0.211365737683265 CG18420 CG18420 K08667|1|2e-24|112|mmu:19144|kallikrein 6 (neurosin, zyme) [EC:3.4.21.-];K01344|2|3e-24|112|gga:395085|protein C (activated) [EC:3.4.21.69];K01320|5|5e-23|108|dre:100038778|coagulation factor VII [EC:3.4.21.21] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43793 4514.00 45 48.825 0.117695042669755 Up 0.274336283185841 bip2 bip2 K13154|1|2e-12|75.5|smm:Smp_127180|U11/U12 small nuclear ribonucleoprotein 31 kDa protein;K02136|2|2e-09|65.9|gga:770146|F-type H+-transporting ATPase subunit gamma [EC:3.6.3.14];K11319|3|6e-06|54.3|rno:312154|inhibitor of growth protein 3 - - - 32443 585.00 2.345 3.42 0.544408402370521 Up 0.32043323206974 CG9072 CG9072 - GO:0015630//microtubule cytoskeleton GO:0005515//protein binding GO:0043623//cellular protein complex assembly 37603 6430.62 13.01 14.015 0.107350782314698 Up 0.195614846123365 robo roundabout, isoform C K06754|1|4e-168|593|mdo:100027033|roundabout, axon guidance receptor 2 GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0016021//integral to membrane;GO:0044297//cell body;GO:0043226//organelle;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0016021//integral to membrane;GO:0044297//cell body;GO:0043226//organelle GO:0004871//signal transducer activity;GO:0005539//glycosaminoglycan binding;GO:0004871//signal transducer activity;GO:0005539//glycosaminoglycan binding GO:0016337//cell-cell adhesion;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0016198//axon choice point recognition;GO:0006928//cellular component movement;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0009790//embryo development;GO:0016337//cell-cell adhesion;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0016198//axon choice point recognition;GO:0006928//cellular component movement;GO:0007431//salivary gland development;GO:0007424//open tracheal system development;GO:0009790//embryo development 31320 4479.61 6.675 7.285 0.126161135489596 Up 0.172632413155462 CG10803 CG10803, isoform E K11089|1|0.0|1237|dme:Dmel_CG10803|60 kDa SS-A/Ro ribonucleoprotein - - - 42354 1789.00 72.9 54.895 -0.409244064296363 Down 0.58133007528728 CG11407 CG11407 K01904|1|4e-44|179|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12];K01896|5|2e-24|114|rno:353317|medium-chain acyl-CoA synthetase [EC:6.2.1.2] - - - 34416 3669.09 59.715 59.8 0.00205211227296145 Up 0.0449742438251222 Cnot4 cnot 4 homologue, isoform L K10643|1|0.0|1665|dme:Dmel_CG31716|CCR4-NOT transcription complex subunit 4 [EC:6.3.2.19] - GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding - 32043 1819.74 4.415 3.015 -0.550255435748381 Down 0.362501651036851 CG42249 CG42249, isoform D K01081|1|0.0|798|dme:Dmel_CG42249|5'-nucleotidase [EC:3.1.3.5] - GO:0016787//hydrolase activity;GO:0043169//cation binding;GO:0016787//hydrolase activity;GO:0043169//cation binding GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process 40040 1325.00 0.035 0.195 2.47804729680464 Up 0.151168934090609 CG12477 CG12477 - - GO:0046914//transition metal ion binding - 39515 918.00 0.34 0.925 1.44391861926597 Up 0.283978338396513 CG10116 CG10116 K01059|1|2e-23|109|dpo:Dpse_GA18274|lipoprotein lipase [EC:3.1.1.34];K01046|3|2e-21|102|nve:NEMVE_v1g83175|triacylglycerol lipase [EC:3.1.1.3] - - GO:0044238//primary metabolic process 36797 2057.92 46.825 39.525 -0.244513531884675 Down 0.433133007528728 mrj mrj, isoform H K09512|1|2e-127|456|dsi:Dsim_GD25559|DnaJ homolog subfamily B member 6 - GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding - 34095 618.87 58.265 49.955 -0.222000426685624 Down 0.420320961563862 baf barrier to autointegration factor, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0051276//chromosome organization 41333 1672.00 128.96 1.505 -6.42101635176827 Down 0.938119138819178 Ugt35b UDP-glycosyltransferase 35b K00699|1|0.0|961|dme:Dmel_CG6649|glucuronosyltransferase [EC:2.4.1.17] - GO:0008194//UDP-glycosyltransferase activity - 42122 742.00 1.45 1.69 0.22097034626725 Up 0.121549332981112 AttD Attacin-D - - - - 38156 840.00 3.09 3.27 0.0816837975937079 Up 0.0860850614185709 msd5 mitotic spindle density 5 - GO:0015630//microtubule cytoskeleton - - 14462389 706.00 0.34 0.01 -5.08746284125034 Down 0.291771232333906 37287 1638.00 2.17 2.64 0.282842886913974 Up 0.185114251750099 CG9864 CG9864, isoform B K08193|1|0.0|953|dme:Dmel_CG9864|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - - 34576 866.00 0.185 0.255 0.462971976342546 Up 0.0833443402456743 CG14930 CG14930 - - GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 41919 4678.00 0.64 0.465 -0.460841188891968 Down 0.121219125610884 spn-E spindle E K13184|1|4e-74|280|nvi:100121353|ATP-dependent RNA helicase A [EC:3.6.4.13] - - - 12798107 407.00 0.01 0.235 4.55458885167764 Up 0.229362039360719 CG43134 CG43134, isoform B - - - - 33045 2827.30 7.195 6.155 -0.225235830255841 Down 0.257264562145027 mal maroon-like, isoform B K06491|1|1e-08|62.4|cin:100183448|neural cell adhesion molecule - GO:0046914//transition metal ion binding;GO:0048037//cofactor binding;GO:0003824//catalytic activity GO:0009108//coenzyme biosynthetic process 4379889 485.00 40.96 123.175 1.58842185119955 Up 0.767500990622111 CG34134 CG34134 - - - - 19835844 425.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 32452 1040.00 0.34 0.46 0.436099114806673 Up 0.103156782459384 CG9101 CG9101 - - - - 50126 420.27 620.76 571.97 -0.118096118179933 Down 0.304021925769383 IM4 immune induced molecule 4, isoform B - GO:0044421//extracellular region part - GO:0002376//immune system process;GO:0006950//response to stress 43768 912.96 1508.375 1420.8 -0.0862916575777466 Down 0.246896050719852 RpS3A ribosomal protein S3A, isoform F K02984|1|3e-102|371|der:Dere_GG16465|small subunit ribosomal protein S3Ae - - - 36230 1208.00 3.385 2.285 -0.566961668516927 Down 0.326376964733853 Tsp47F tetraspanin 47F K06497|1|2e-37|155|ame:552721|CD63 antigen GO:0031224//intrinsic to membrane - - 3771978 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 32786 3449.98 22.415 18.635 -0.266449680321838 Down 0.414872539955092 CG7536 CG7536, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0004871//signal transducer activity - 35845 1803.00 3.015 2.23 -0.43511429197978 Down 0.264562145027077 CG8642 CG8642 K10104|1|2e-47|189|dwi:Dwil_GK15354|ficolin GO:0044421//extracellular region part GO:0005515//protein binding GO:0023060 39596 3761.00 11.74 8.215 -0.515099928159978 Down 0.495509179764892 dlp dally-like, isoform C K08110|1|3e-108|394|dpo:Dpse_GA16712|glypican 4 (K-glypican) GO:0031224//intrinsic to membrane;GO:0031012//extracellular matrix;GO:0031224//intrinsic to membrane;GO:0031012//extracellular matrix GO:0043394//proteoglycan binding;GO:0043394//proteoglycan binding GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0010259//multicellular organismal aging;GO:0009584//detection of visible light;GO:0001654//eye development;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0010259//multicellular organismal aging;GO:0009584//detection of visible light;GO:0001654//eye development;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007476//imaginal disc-derived wing morphogenesis 14462473 776.00 661.475 481.335 -0.458645299987434 Down 0.634130233786818 38635 2653.00 16.32 17.02 0.0605899797144669 Up 0.137597411174217 CG10590 CG10590 - GO:0031224//intrinsic to membrane - - 40286 3413.00 0.34 0.345 0.0210616155278296 Up 0.0413749834896315 CG13251 CG13251 - - - - 53443 2576.00 59.345 60.935 0.038144641583391 Up 0.129342226918505 SF2 SF2, isoform B K12890|1|7e-78|291|dya:Dyak_GE26323|splicing factor, arginine/serine-rich 1/9 GO:0005681//spliceosomal complex GO:0003723//RNA binding GO:0000245//spliceosomal complex assembly 19834751 319.00 1.595 0.315 -2.34013269026495 Down 0.438383304715361 33630 795.00 1.58 2.2 0.477578965347557 Up 0.239202218993528 CG15425 CG15425 - - - - 33108 3638.54 18.63 18.275 -0.0277562681018379 Down 0.0906419231277242 CG1486 CG1486, isoform B K01594|1|2e-09|65.9|mdo:100010648|sulfinoalanine decarboxylase [EC:4.1.1.29];K01590|5|2e-08|62.0|spu:548615|histidine decarboxylase [EC:4.1.1.22] - GO:0016830//carbon-carbon lyase activity;GO:0048037//cofactor binding;GO:0016830//carbon-carbon lyase activity;GO:0048037//cofactor binding GO:0043436;GO:0043436 33931 1452.00 8.695 10.3 0.244386404763994 Up 0.310262845066702 CG31633 CG31633 - - - - 33479 1193.00 5.875 3.445 -0.770084868748071 Down 0.476357152291639 CG3119 CG3119, isoform B K00731|1|1e-27|122|dgr:Dgri_GH23406|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part;GO:0044464//cell part GO:0016740//transferase activity - 14462760 1486.00 18.765 17.06 -0.137426643568686 Down 0.258288204992735 36118 5781.84 38.02 45.76 0.267328520129837 Up 0.461035530313037 psq pipsqueak, isoform M K02174|1|2e-31|139|dme:Dmel_CG11491|broad;K09237|2|1e-27|126|tca:659978|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior;GO:0007472//wing disc morphogenesis;GO:0009987//cellular process;GO:0007635//chemosensory behavior 36162 483.00 0.09 0.305 1.76081233612057 Up 0.167250033020737 Obp47a Odorant-binding protein 47a, isoform B - - GO:0005488//binding;GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization;GO:0007600//sensory perception;GO:0051234//establishment of localization 38327 4927.45 21.13 25.29 0.259274269728298 Up 0.415466913221503 MEP-1 MEP-1, isoform G - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016887//ATPase activity;GO:0046914//transition metal ion binding;GO:0016887//ATPase activity;GO:0046914//transition metal ion binding;GO:0016887//ATPase activity;GO:0046914//transition metal ion binding;GO:0016887//ATPase activity;GO:0046914//transition metal ion binding;GO:0016887//ATPase activity;GO:0046914//transition metal ion binding;GO:0016887//ATPase activity;GO:0046914//transition metal ion binding;GO:0016887//ATPase activity GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis 44936 11582.90 24.06 18.81 -0.355136793652881 Down 0.493428873332453 Eip93F Ecdysone-induced protein 93F, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0008624;GO:0035071//salivary gland cell autophagic cell death;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044248//cellular catabolic process;GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0008624;GO:0035071//salivary gland cell autophagic cell death;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044248//cellular catabolic process 32530 1902.26 22.435 26.51 0.240785486190914 Up 0.399154669132215 mRpS30 mitochondrial ribosomal protein S30, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex;GO:0015630//microtubule cytoskeleton GO:0005198//structural molecule activity GO:0010467//gene expression 246395 1323.00 0.1 0.52 2.37851162325373 Up 0.257693831726324 mthl13 methuselah-like 13 K04599|1|2e-34|139|dpo:Dpse_GA19967|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus 8674068 1887.00 1.37 0.9 -0.606178986630852 Down 0.21536124686303 CG42516 CG42516, isoform C - GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding GO:0006383//transcription from RNA polymerase III promoter;GO:0034622;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0034622;GO:0006366//transcription from RNA polymerase II promoter 36555 5553.49 22.59 24.605 0.123267245737055 Up 0.248348963148857 mam mastermind, isoform D K06061|1|1e-74|280|dme:Dmel_CG8118|mastermind GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0051301//cell division;GO:0019827//stem cell maintenance;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0001654//eye development;GO:0001709//cell fate determination;GO:0051301//cell division;GO:0019827//stem cell maintenance;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0001654//eye development;GO:0001709//cell fate determination;GO:0051301//cell division;GO:0019827//stem cell maintenance;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0001654//eye development;GO:0001709//cell fate determination 43839 5713.94 64.2 66.01 0.0401113007230351 Up 0.130630035662396 eIF4G eukaryotic translation initiation factor 4G, isoform C K03260|1|0.0|2798|dme:Dmel_CG10811|translation initiation factor eIF-4F - - - 32233 10665.53 6.165 7.3 0.243795569364541 Up 0.270902126535464 Pde9 phosphodiesterase 9, isoform F K13761|1|0.0|1779|dme:Dmel_CG42276|high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] - GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding GO:0023060;GO:0023060 12798569 296.00 0.605 1.025 0.760616862230851 Up 0.212191256108836 CG43307 CG43307 - - - - 41198 2049.66 1.49 2.005 0.428289905992759 Up 0.212257297582882 Whamy whamy, isoform E - - - - 42264 648.00 5.59 6.275 0.166767175994944 Up 0.195978074230617 CG14292 CG14292 - - - - 35341 2353.00 0.175 0.37 1.08017034868398 Up 0.148626337339849 cad caudal, isoform C K09312|1|6e-129|461|dme:Dmel_CG1759|homeobox protein CDX GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0010468//regulation of gene expression;GO:0010004//gastrulation involving germ band extension;GO:0009798//axis specification;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0035215//genital disc development;GO:0010468//regulation of gene expression;GO:0010004//gastrulation involving germ band extension;GO:0009798//axis specification;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0035215//genital disc development 32168 1620.00 9.63 7.985 -0.270243390432227 Down 0.325386342623167 Tango4 transport and golgi organization 4 K12862|1|0.0|920|dme:Dmel_CG1796|pleiotropic regulator 1 GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part - GO:0000377 40256 1543.00 39.725 43.105 0.117808006047349 Up 0.270571919165236 CG5282 CG5282 K01273|1|4e-52|206|dme:Dmel_CG6154|membrane dipeptidase [EC:3.4.13.19] - GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process 37313 515.00 22.745 41.955 0.883293319905693 Up 0.683859463743231 CG13422 CG13422 - - - - 36167 1492.89 0.775 0.805 0.0547924728403796 Up 0.0483423590014529 BBS4 Bardet-Biedl syndrome 4 ortholog, isoform B K09667|1|2e-10|67.0|tca:655930|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] GO:0005813//centrosome;GO:0042995//cell projection GO:0003774//motor activity;GO:0005488//binding GO:0048513//organ development;GO:0030030//cell projection organization;GO:0031023//microtubule organizing center organization;GO:0007399//nervous system development;GO:0010927;GO:0065007//biological regulation 39274 1642.55 6.37 6.915 0.118435878894194 Up 0.158862765816933 CG6163 CG6163, isoform B - - - - 42867 2008.00 22.785 21.375 -0.092159950562617 Down 0.195879012019548 CG6178 CG6178 K01904|1|1e-104|380|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12] - GO:0016408;GO:0015645//fatty acid ligase activity;GO:0004497//monooxygenase activity GO:0035337 40786 2151.00 7.285 5.025 -0.535805375998222 Down 0.436005811649716 CG10286 CG10286 - - - - 37455 5825.14 16.895 14.78 -0.192950081017651 Down 0.313730022454101 Egfr epidermal growth factor receptor, isoform B K04361|1|0.0|2782|dme:Dmel_CG10079|epidermal growth factor receptor [EC:2.7.10.1] - - - 34330 3276.00 3.185 3.24 0.0247004406283244 Up 0.0528001584995377 bib big brain, isoform B K09866|1|7e-27|123|dre:445293|aquaporin-4;K09865|3|7e-25|116|ecb:100059758|aquaporin-2 GO:0016021//integral to membrane GO:0005216//ion channel activity GO:0006810//transport;GO:0009888//tissue development;GO:0006996//organelle organization;GO:0051452//intracellular pH reduction;GO:0007155//cell adhesion;GO:0032501//multicellular organismal process;GO:0003006//developmental process involved in reproduction 19836222 469.00 0.73 0.55 -0.408464845355357 Down 0.122110685510501 33838 2934.65 7.665 6.905 -0.150644377400727 Down 0.199412230880993 Tsp26A tetraspanin 26A, isoform D K10303|1|4e-173|608|dpo:Dpse_GA21537|F-box protein 23 GO:0031224//intrinsic to membrane - - 43923 7540.83 12.75 10.55 -0.273254248151673 Down 0.360685510500594 axo axotactin, isoform I K07380|1|1e-65|253|xtr:780189|contactin associated protein-like 2 - GO:0005515//protein binding;GO:0004866//endopeptidase inhibitor activity GO:0023060 36254 1803.00 0.04 0.03 -0.415037499278844 Down 0.0473847576277902 Ir48b ionotropic receptor 48b - - - - 36249 1695.00 1.305 7.69 2.55893379139194 Up 0.691256108836349 Tret1-2 trehalose transporter 1-2 K08145|1|2e-97|356|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane GO:0015151//alpha-glucoside transmembrane transporter activity GO:0000017//alpha-glucoside transport 42290 456.00 30.75 34.15 0.151299168063488 Up 0.309140140007925 mRpL55 mitochondrial ribosomal protein L55 - GO:0000315//organellar large ribosomal subunit;GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression 36671 1377.00 10.085 16.105 0.675297576769853 Up 0.58317923656056 CG10257 CG10257 - - - GO:0006915//apoptotic process 35649 2459.00 0.36 0.355 -0.0201778819376304 Down 0.0413749834896315 Incenp inner centromere protein, isoform C K11515|1|5e-09|63.5|ecb:100059935|inner centromere protein GO:0044427//chromosomal part;GO:0044430//cytoskeletal part GO:0005488//binding GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0030261//chromosome condensation;GO:0051255//spindle midzone assembly;GO:0007059//chromosome segregation;GO:0051301//cell division;GO:0007143//female meiosis;GO:0033036;GO:0007140//male meiosis;GO:0051303//establishment of chromosome localization 19835873 412.00 0.21 0.12 -0.807354922057604 Down 0.0982366926429798 39775 1862.00 56.14 63.835 0.185318590252087 Up 0.38647470611544 CG5027 CG5027 K09585|1|0.0|826|dse:Dsec_GM25596|thioredoxin domain-containing protein 10 [EC:5.3.4.1] GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0019725//cellular homeostasis 19835416 2873.00 0.39 0.445 0.190331212104149 Up 0.0653810593052437 246465 1224.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 CG30114 CG30114 - - - - 35282 1082.85 199.06 193.81 -0.0385603373350946 Down 0.136309602430326 CG10680 CG10680, isoform B - - - - 14462800 422.63 11.45 17.45 0.607879438112708 Up 0.573405098401796 42828 1501.97 125.92 78.425 -0.683121916776521 Down 0.67979791308942 Pros26.4 regulatory particle triple-A ATPase 2, isoform B K03062|1|0.0|843|dsi:Dsim_GD18337|26S proteasome regulatory subunit T2 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0033554//cellular response to stress;GO:0007052//mitotic spindle organization 32840 1501.63 0.79 1.895 1.26227328999399 Up 0.373827763835689 CG6470 CG6470, isoform B - - GO:0046914//transition metal ion binding - 2768684 660.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 CG33342 HDC15381, isoform C - - - - 39136 2146.00 17.48 16.315 -0.0995061974087341 Down 0.196671509708097 SH3PX1 SH3PX1 ortholog K04438|1|4e-06|53.5|isc:IscW_ISCW020669|proto-oncogene C-crk - GO:0005543//phospholipid binding GO:0009987//cellular process 3772646 4439.95 0.81 1.235 0.608517228700053 Up 0.202218993527936 mei-218 meiotic 218, isoform E - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0032559;GO:0003676//nucleic acid binding;GO:0032559;GO:0003676//nucleic acid binding;GO:0032559;GO:0003676//nucleic acid binding;GO:0032559 GO:0006310//DNA recombination;GO:0006310//DNA recombination;GO:0006310//DNA recombination;GO:0006310//DNA recombination 14462675 571.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 43809 2788.36 44.6 46.57 0.0623571720126613 Up 0.166754721965394 Slip1 Slip1, isoform C K05701|1|7e-07|56.6|rno:292994|tight junction protein 1;K04237|2|4e-06|54.3|hmg:100212317|partitioning defective protein 3 - - - 36245 543.00 0.245 0.285 0.218180170049533 Up 0.0618148197067759 CG13198 CG13198 K12602|1|4e-06|50.8|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 38712 720.00 0.115 0.27 1.23132554610646 Up 0.137993660018492 Cpr65Az cuticular protein 65Az - - GO:0005198//structural molecule activity - 34260 1302.00 4.985 7.365 0.563092020637653 Up 0.44670453044512 FucTB FucTB, isoform D K09669|1|0.0|928|dme:Dmel_CG4435|alpha-1,3-fucosyltransferase 10 [EC:2.4.1.-] GO:0000139//Golgi membrane;GO:0031224//intrinsic to membrane GO:0008417//fucosyltransferase activity GO:0006464//cellular protein modification process 38005 1649.00 0.05 0.03 -0.736965594166206 Down 0.0552767137762515 gsb gooseberry K09381|1|5e-172|604|dme:Dmel_CG3388|paired box protein 3/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007417//central nervous system development;GO:0010468//regulation of gene expression;GO:0007365//periodic partitioning;GO:0007431//salivary gland development;GO:0006351//transcription, DNA-dependent 38615 543.00 51.14 57.555 0.1704891050823 Up 0.356756042794875 CG10635 CG10635 K09550|1|8e-59|225|dme:Dmel_CG10635|prefoldin subunit 4 GO:0043234//protein complex GO:0005515//protein binding GO:0044267//cellular protein metabolic process 44978 1882.76 42.935 42.03 -0.0307347352840892 Down 0.105237088891824 Tom40 translocase of outer membrane 40, isoform C K11518|1|4e-166|585|dme:Dmel_CG12157|mitochondrial import receptor subunit TOM40 GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0004871//signal transducer activity;GO:0008320//protein transmembrane transporter activity;GO:0005244//voltage-gated ion channel activity;GO:0004871//signal transducer activity;GO:0008320//protein transmembrane transporter activity;GO:0005244//voltage-gated ion channel activity GO:0006811//ion transport;GO:0006605//protein targeting;GO:0006811//ion transport;GO:0006605//protein targeting 33039 978.00 5.14 13.45 1.38776590825011 Up 0.67273147536653 Obp19c Odorant-binding protein 19c, isoform C - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 19835711 747.00 0.165 0.125 -0.400537929583729 Down 0.0673292827895919 38515 3207.00 0.05 0.095 0.925999418556223 Up 0.0698718795403513 pav pavarotti K10402|1|0.0|951|aag:AaeL_AAEL002714|kinesin family member 20/23 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005875//microtubule associated complex GO:0032559;GO:0003774//motor activity GO:0000278//mitotic cell cycle;GO:0007166//cell surface receptor signaling pathway;GO:0007017//microtubule-based process;GO:0007143//female meiosis;GO:0045165//cell fate commitment;GO:0045185//maintenance of protein location;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007399//nervous system development;GO:0035466;GO:0042993//positive regulation of transcription factor import into nucleus 39688 1714.00 5.19 5.04 -0.0423108048579642 Down 0.0723484348170651 mrn marionette K03144|1|0.0|974|dse:Dsec_GM24480|transcription initiation factor TFIIH subunit H4 GO:0005667//transcription factor complex GO:0030528//transcription regulator activity GO:0006259//DNA metabolic process;GO:0006352//DNA-dependent transcription, initiation 39717 2077.87 18.76 17.24 -0.121900053426278 Down 0.231475366530181 comm commissureless, isoform B - GO:0016023//cytoplasmic membrane-bounded vesicle GO:0019904//protein domain specific binding GO:0002090//regulation of receptor internalization;GO:0016198//axon choice point recognition;GO:0006928//cellular component movement 37724 2738.00 11.305 16.595 0.553787637326771 Up 0.549960375115573 bw brown, isoform D K05679|1|6e-27|123|rno:85264|ATP-binding cassette, subfamily G (WHITE), member 1 GO:0043234//protein complex;GO:0016021//integral to membrane GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0032559 GO:0006810//transport;GO:0042441//eye pigment metabolic process;GO:0019889//pteridine metabolic process 47730 1240.00 8.455 10.385 0.296624556434664 Up 0.360157178708229 CG12253 CG12253 - - - - 49297 3718.97 1113.13 819.255 -0.442237613866217 Down 0.625610883634923 Ca-P60A calcium ATPase at 60A, isoform I K05853|1|0.0|1853|dse:Dsec_GM15491|Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0043169//cation binding GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206;GO:0032879//regulation of localization;GO:0070838//divalent metal ion transport;GO:0007268//synaptic transmission;GO:0009206 39960 833.00 3.14 0.215 -3.86835599418953 Down 0.631653678510104 CG7542 CG7542, isoform B K01310|1|2e-51|202|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|3|3e-45|181|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41180 3190.00 4.055 3.515 -0.206177225144738 Down 0.183991546691322 dmt dalmatian - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding GO:0000278//mitotic cell cycle;GO:0048731;GO:0006351//transcription, DNA-dependent 34592 5923.84 38.425 38.505 0.00300053671844097 Up 0.0449742438251222 crol crooked legs, isoform I K09228|1|3e-113|411|ptr:452393|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0007346//regulation of mitotic cell cycle;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0007346//regulation of mitotic cell cycle;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0007346//regulation of mitotic cell cycle;GO:0016055//Wnt receptor signaling pathway;GO:0007472//wing disc morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0007346//regulation of mitotic cell cycle 19836228 750.00 0.215 0.18 -0.256339753259786 Down 0.0637300224541012 - CG45413, isoform B - - - - 40393 1822.00 0.625 0.475 -0.395928676331139 Down 0.111808215559371 capaR capability receptor, isoform C K05053|1|3e-50|200|mmu:216749|neuromedin U receptor 2;K05052|3|1e-49|198|tgu:100220192|neuromedin U receptor 1 GO:0016021//integral to membrane GO:0008188//neuropeptide receptor activity;GO:0001608 GO:0046903//secretion;GO:0007166//cell surface receptor signaling pathway;GO:0023060 32195 1581.77 14.725 14.725 0 - 0.0382380134724607 Rab40 Rab40, isoform C K07928|1|2e-150|532|dpe:Dper_GL25374|Ras-related protein Rab-40 - GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding GO:0065008;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0065008;GO:0006810//transport;GO:0035556//intracellular signal transduction 40128 2156.00 5.09 4.69 -0.118077733560319 Down 0.138885219918109 CG9300 CG9300 - GO:0043231//intracellular membrane-bounded organelle - - 251466 320.00 2428.335 2251.75 -0.108920800309562 Down 0.287808743891164 RpL41 ribosomal protein L41 - - - - 19835538 207.00 1.48 1.23 -0.26693886028971 Down 0.130530973451327 37726 1221.00 0.04 0.04 0 - 0.0382380134724607 Gr59f gustatory receptor 59f K08471|1|1e-07|57.8|dme:Dmel_CG33151|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 3772494 755.00 0.66 0.6 -0.137503523749935 Down 0.0661405362567692 CG33679 CG33679 K12602|1|6e-08|57.8|dpo:Dpse_GA17766|WD repeat-containing protein 61;K09255|2|2e-06|52.8|dpe:Dper_GL18753|Rel/ankyrin family, other - - - 31329 2579.09 4.14 4.885 0.23872779446906 Up 0.224243825122177 Parg Poly(ADP-ribose) glycohydrolase, isoform C K07759|1|0.0|1348|dme:Dmel_CG2864|poly(ADP-ribose) glycohydrolase [EC:3.2.1.143] - - - 38506 2648.00 0.6 0.135 -2.15200309344505 Down 0.268557654206842 CG15005 CG15005 K12797|1|2e-06|55.1|mmu:239319|caspase recruitment domain-containing protein 6;K04705|2|6e-06|53.5|dme:Dmel_CG6521|signal transducing adaptor molecule - - - 42500 1722.00 10.31 8.52 -0.27511899714227 Down 0.341962752608638 rtet tetracycline resistance K08214|1|8e-13|75.5|gga:423089|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18;K12307|2|1e-12|74.7|ptr:471303|MFS transporter, ceroid-lipofuscinosis neuronal protein 7 GO:0044464//cell part GO:0015144//carbohydrate transmembrane transporter activity GO:0006810//transport 50169 1608.00 0.52 0.815 0.648288436089985 Up 0.170320961563862 CG18675 CG18675 - - - - 35348 1137.95 20.815 25.725 0.305547518641113 Up 0.462356359793951 CG31673 CG31673, isoform B K00049|1|4e-85|315|dme:Dmel_CG31674|glyoxylate reductase (NADP+) [EC:1.1.1.79];K00015|3|1e-56|220|hsa:9380|glyoxylate reductase [EC:1.1.1.26];K00058|4|3e-29|129|cbr:CBG20736|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] - GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding - 36036 1094.00 0.045 0.045 0 - 0.0382380134724607 CG12133 CG12133 K01362|1|0.0|666|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|2e-27|123|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34654 1326.00 2.725 2.025 -0.428334321892302 Down 0.249669792629771 CG6405 CG6405 - - - - 338392 1295.47 17.48 18.4 0.0740005814437771 Up 0.156089023907014 CG33932 CG33932, isoform B K01164|1|6e-20|98.6|oaa:100088536|ribonuclease P [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle;GO:0030677//ribonuclease P complex GO:0005488//binding;GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process 37914 3921.97 61.615 67.655 0.134914945841627 Up 0.301314225333509 CG4612 CG4612, isoform C K13126|1|2e-60|233|tca:657776|polyadenylate-binding protein 1 GO:0015630//microtubule cytoskeleton;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part GO:0003729//mRNA binding GO:0006412//translation;GO:0003002//regionalization;GO:0007126//meiosis;GO:0007267//cell-cell signaling;GO:0000377;GO:0007292//female gamete generation 31799 1959.74 14.96 12.07 -0.309684499132615 Down 0.412594109100515 CG12081 CG12081, isoform B K01787|1|1e-22|108|mcc:698140|N-acylglucosamine 2-epimerase [EC:5.1.3.8];K10317|4|4e-14|80.1|nve:NEMVE_v1g100198|F-box protein 42 GO:0000785//chromatin GO:0005488//binding - 45587 5044.00 1.43 0.74 -0.95041797114944 Down 0.286586976621318 nompA no mechanoreceptor potential A, isoform F - GO:0044421//extracellular region part;GO:0044421//extracellular region part;GO:0044421//extracellular region part;GO:0044421//extracellular region part - GO:0007600//sensory perception;GO:0048812//neuron projection morphogenesis;GO:0007600//sensory perception;GO:0048812//neuron projection morphogenesis;GO:0007600//sensory perception;GO:0048812//neuron projection morphogenesis;GO:0007600//sensory perception;GO:0048812//neuron projection morphogenesis 318891 2094.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG33124 CG33124 K03307|1|5e-101|368|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport 37938 1736.00 6.745 5.975 -0.174879730080157 Down 0.207634394399683 CG3608 CG3608, isoform B K08869|1|0.0|1004|dme:Dmel_CG3608|aarF domain-containing kinase - GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process 14462556 444.00 0.285 0.59 1.0497530351971 Up 0.189836217144367 CG43646 CG43646 - - - - 36159 547.84 221.77 251.48 0.181379450513468 Up 0.397404570070004 CG7712 CG7712, isoform B K03950|1|4e-67|253|dsi:Dsim_GD15256|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 6 [EC:1.6.5.3 1.6.99.3] - GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain 3355171 2001.00 4.22 6.145 0.542170011665476 Up 0.411207238145555 FucTC FucTC K00753|1|8e-41|162|api:100161726|glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214] GO:0000139//Golgi membrane;GO:0031224//intrinsic to membrane GO:0008417//fucosyltransferase activity GO:0006464//cellular protein modification process 50160 409.00 20.735 27.64 0.414689568482297 Up 0.533813234711399 CG14645 CG14645 - - GO:0030247//polysaccharide binding GO:0006022 246386 887.00 17.255 20.175 0.225554199729627 Up 0.36735569937921 GstT2 glutathione S transferase T2 K00799|1|1e-53|209|dme:Dmel_CG1702|glutathione S-transferase [EC:2.5.1.18] - - - 32520 1735.60 5.135 4.69 -0.130776353802819 Down 0.150046229031832 CG8239 CG8239, isoform B K01597|1|0.0|757|dme:Dmel_CG8239|diphosphomevalonate decarboxylase [EC:4.1.1.33] - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016831//carboxy-lyase activity;GO:0032559 GO:0006720//isoprenoid metabolic process;GO:0006796//phosphate-containing compound metabolic process 318604 1532.00 4.095 3.715 -0.140501241102413 Down 0.141460837405891 Slimp Seryl-tRNA synthetase-like insect mitochondrial protein K01875|1|0.0|929|dme:Dmel_CG31133|seryl-tRNA synthetase [EC:6.1.1.11] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 34440 1966.89 6.135 6.49 0.0811551343362337 Up 0.117983093382644 RluA-2 RluA-2, isoform E K01718|1|0.0|1108|dme:Dmel_CG6187|pseudouridylate synthase [EC:4.2.1.70];K06043|1|0.0|1108|dme:Dmel_CG6187|tRNA-pseudouridine synthase I [EC:5.4.99.12] - GO:0016866//intramolecular transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0015923//mannosidase activity;GO:0016866//intramolecular transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0015923//mannosidase activity;GO:0016866//intramolecular transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0015923//mannosidase activity GO:0006771//riboflavin metabolic process;GO:0009451//RNA modification;GO:0019318//hexose metabolic process;GO:0006771//riboflavin metabolic process;GO:0009451//RNA modification;GO:0019318//hexose metabolic process;GO:0006771//riboflavin metabolic process;GO:0009451//RNA modification;GO:0019318//hexose metabolic process 44441 1710.00 15.155 14.565 -0.0572881506439805 Down 0.130035662395985 Bem46 Bem46 K06889|1|0.0|647|dme:Dmel_CG18642| - GO:0003824//catalytic activity - 38833 975.00 0.205 0.4 0.964376090269279 Up 0.147635715229164 sphinx2 sphinx2 K01310|1|3e-30|132|dme:Dmel_CG18179|chymotrypsin [EC:3.4.21.1];K01362|2|2e-21|102|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42299 966.00 11.85 12.53 0.0804993555362388 Up 0.151598203671906 CG42359 CG42359 - - - - 35854 1587.46 96.255 54.065 -0.832166543629479 Down 0.700501915202747 CG8586 CG8586, isoform C K01324|1|4e-29|129|mmu:16621|plasma kallikrein [EC:3.4.21.34] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42488 1016.46 51.165 44.21 -0.210784521380494 Down 0.403744551578391 CG7079 CG7079, isoform B K12347|1|2e-22|105|dan:Dana_GF18523|natural resistance-associated macrophage protein - - - 37124 1453.00 8.995 11.555 0.361322073216149 Up 0.416721701228371 CG5190 CG5190 - - - - 10178814 803.00 27.735 26.995 -0.0390155086760953 Down 0.116992471271959 CG42806 CG42806 K01365|1|8e-06|50.4|dan:Dana_GF13722|cathepsin L [EC:3.4.22.15] - - - 42944 5356.48 34.695 31.805 -0.125474180174095 Down 0.279817725531634 tok tolkin, isoform C K13046|1|0.0|2729|dme:Dmel_CG6863|tolkin [EC:3.4.24.-] GO:0044464//cell part;GO:0044464//cell part GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0007411//axon guidance;GO:0007414//axonal defasciculation;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016485//protein processing;GO:0007411//axon guidance;GO:0007414//axonal defasciculation;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016485//protein processing 318972 1225.00 0.27 0.42 0.637429920615292 Up 0.118181217804781 CG31835 CG31835 - GO:0044464//cell part GO:0046914//transition metal ion binding - 34022 1174.00 105.75 66.865 -0.661334518061974 Down 0.672797516840576 CG5958 CG5958 K10693|1|1e-09|64.3|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K01104|2|7e-06|51.6|dre:560176|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044444//cytoplasmic part - GO:0051234//establishment of localization 317902 430.00 0.45 0.27 -0.736965594166206 Down 0.133998150838727 CG32189 CG32189 - - - - 33619 6152.04 32.165 26.58 -0.275150584070464 Down 0.451525558050456 ed echinoid, isoform C K06491|1|2e-30|135|tgu:100222905|neural cell adhesion molecule;K06762|2|6e-30|134|rno:116658|contactin 4;K06255|4|3e-29|132|cfa:403440|heparan sulfate proteoglycan 2 (perlecan) GO:0044464//cell part - - 39011 702.00 0.06 0.14 1.22239242133645 Up 0.0986989829612997 CG13308 CG13308 - - GO:0030247//polysaccharide binding GO:0006022 42070 925.00 0.09 0.05 -0.84799690655495 Down 0.0698718795403513 CG4053 CG4053 K11997|1|2e-34|145|ame:409206|tripartite motif-containing protein 2/3;K09641|2|8e-32|137|mcc:711510|transmembrane protease, serine 11D [EC:3.4.21.-];K01312|3|6e-30|130|dpo:Dpse_GA15051|trypsin [EC:3.4.21.4];K01362|4|1e-29|129|dme:Dmel_CG2071| [EC:3.4.21.-] - - - 246535 1648.00 1.19 1.605 0.43161172381436 Up 0.191586316206578 Cht12 Cht12 K01183|1|0.0|994|dme:Dmel_CG30293|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding GO:0006026 8673977 416.57 0.885 0.995 0.169019070460652 Up 0.0841698586712455 CG42586 CG42586, isoform B - - - - 41057 1150.55 22.315 19.88 -0.166696049689569 Down 0.310031699907542 CG9837 CG9837, isoform F - - - - 46027 1735.51 7.525 6.955 -0.113641067104825 Down 0.157872143706248 kermit kermit, isoform E - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction 19835338 783.00 0.055 0.24 2.12553088208386 Up 0.162726192048607 31192 1889.06 36.27 29.37 -0.304433479645429 Down 0.48018755778629 Cyp4d2 cytochrome P450-4d2, isoform B K00517|1|0.0|985|dme:Dmel_CG3466| [EC:1.14.-.-] - - - 40912 6650.00 10.24 12.435 0.280190792216907 Up 0.366530180953639 CG34127 CG34127, isoform C K07378|1|0.0|968|aga:AgaP_AGAP003568|neuroligin - - - 7354382 662.99 77.28 78.485 0.0223218592772876 Up 0.0889578655395588 CG42305 CG42305, isoform C - - - - 10178877 3500.00 0.075 0.01 -2.90689059560852 Down 0.100680227182671 CG42818 CG42818 - - - - 42514 1995.83 8.305 9.76 0.23290097960051 Up 0.296295073306036 Snmp1 sensory neuron membrane protein 1, isoform B K13885|1|7e-45|182|mdo:100029588|scavenger receptor class B, member 1;K12384|2|5e-44|179|gga:422638|lysosome membrane protein 2 GO:0043005//neuron projection;GO:0016021//integral to membrane;GO:0044297//cell body GO:0004888//transmembrane signaling receptor activity GO:0010033//response to organic substance;GO:0006950//response to stress;GO:0023033;GO:0009987//cellular process 40683 2836.84 37.26 37.445 0.00714541538477697 Up 0.0600977413815876 Rga regena, isoform C K12605|1|4e-117|422|der:Dere_GG10926|CCR4-NOT transcription complex subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 35861 657.01 1.08 1.315 0.284031487128834 Up 0.12627129837538 PGRP-SC1b PGRP-SC1b, isoform B K01446|1|1e-99|362|dme:Dmel_CG8577|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0009581//detection of external stimulus 37033 6129.22 8.43 10.255 0.28272295553777 Up 0.344010038304055 fab1 fab1, isoform B K00921|1|0.0|3325|dme:Dmel_CG6355|1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150] - - - 318079 1978.82 5.17 4.88 -0.0832831327520484 Down 0.106260731739532 CG32537 CG32537, isoform B - - - GO:0006810//transport 42323 1815.00 0.93 0.515 -0.852658283924813 Down 0.214139479593185 CG11626 CG11626 K01285|1|0.0|702|dme:Dmel_CG11626|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2];K09649|2|1e-26|121|mmu:54373|protease, serine, 16 (thymus) [EC:3.4.-.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 37297 1384.67 365.365 294.915 -0.309039235382832 Down 0.542530709285431 CG9090 CG9090, isoform C K03454|1|5e-13|75.9|tad:TRIADDRAFT_25969|mitochondrial carrier protein, MC family;K08769|5|2e-11|70.5|mcc:574124|mitochondrial brown fat uncoupling protein 1 - - - 39467 1774.00 0.325 0.385 0.244418727666447 Up 0.0707634394399683 CG10752 CG10752 K10442|1|5e-12|72.8|aag:AaeL_AAEL008102|kelch-like protein 1/4/5;K13956|3|6e-10|65.9|tgu:100227112|actin-binding protein IPP - - - 39682 4498.00 5.73 4.285 -0.419239934644405 Down 0.34916127327962 CrebA Cyclic-AMP response element binding protein A, isoform B K09048|1|3e-36|154|aag:AaeL_AAEL000402|cAMP response element-binding protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0003002//regionalization;GO:0006355//regulation of transcription, DNA-dependent;GO:0007431//salivary gland development;GO:0008363//larval chitin-based cuticle development;GO:0003002//regionalization;GO:0006355//regulation of transcription, DNA-dependent;GO:0007431//salivary gland development;GO:0008363//larval chitin-based cuticle development 12798272 319.00 0.435 2.79 2.68117781598046 Up 0.557423061682737 CG43117 CG43117 - - - - 3771816 1023.00 0.495 0.025 -4.30742852519225 Down 0.31812178047814 His1:CG33816 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 34585 1330.00 2.3 3.44 0.580774703757723 Up 0.333014132875446 CG4983 CG4983, isoform B K10838|1|1e-06|54.3|dme:Dmel_CG8153|xeroderma pigmentosum group C-complementing protein;K12035|2|9e-06|51.6|aga:AgaP_AGAP007135|tripartite motif-containing protein 71 - - - 34543 2992.66 12.895 12.085 -0.0935943000236312 Down 0.168075551446308 l(2)gd1 lethal (2) giant discs 1, isoform B - GO:0044459//plasma membrane part;GO:0044424//intracellular part GO:0008289//lipid binding GO:0001654//eye development;GO:0008593//regulation of Notch signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008356//asymmetric cell division;GO:0006897//endocytosis;GO:0015031//protein transport 36133 4784.11 14.855 15.405 0.0524500772039368 Up 0.119303922863558 wde windei, isoform B - - - - 12798420 435.00 0.495 0.265 -0.90143616551641 Down 0.157277770439836 CG43244 CG43244 - - - - 39193 1918.62 0.88 1.655 0.91125578816992 Up 0.300719852067098 CG12362 CG12362, isoform B K11968|1|0.0|1095|dme:Dmel_CG12362|ariadne-1 - GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity - 34822 2206.00 8.24 0.735 -3.48682818234685 Down 0.738805970149254 CG4500 CG4500 K01897|1|8e-37|155|spu:581020|long-chain acyl-CoA synthetase [EC:6.2.1.3] - - GO:0009888//tissue development 37410 4191.94 27.245 30.11 0.14425121714815 Up 0.290714568749175 CG30389 CG30389, isoform F K13191|1|0.0|645|dsi:Dsim_GD25221|RNA-binding protein 16;K10352|3|3e-08|61.6|hmg:100205834|myosin heavy chain - - - 33098 1920.23 248.795 111.44 -1.15869032905784 Down 0.746565843349624 CG32521 CG32521, isoform I - - - - 43595 272.00 11.96 23.63 0.982402239775742 Up 0.667547219653943 Anp andropin, isoform B - - - GO:0050831//male-specific defense response to bacterium;GO:0002815 35339 3019.00 8.15 8.475 0.0564133089052663 Up 0.104345528992207 CG9323 CG9323, isoform B K13185|1|9e-115|415|xtr:779538|ATP-dependent RNA helicase DHX30 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled - 14462693 438.00 0.575 0.325 -0.823122237915921 Down 0.161504424778761 CG43774 CG43774 - - - - 40284 579.00 0.23 0.49 1.0911478880582 Up 0.17481178179897 CG13250 CG13250, isoform B - - - - 32894 682.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG7423 CG7423 K10380|1|1e-10|65.9|cel:B0350.2|ankyrin;K10799|3|5e-10|63.9|bmy:Bm1_32600|tankyrase [EC:2.4.2.30] - - - 42164 771.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 CG14315 CG14315 - - - - 14462350 950.07 5.845 6.565 0.16759198636123 Up 0.201261392154273 31316 2465.29 0.88 1.075 0.288761230952163 Up 0.120261524237221 CG12206 CG12206, isoform C - - - - 246529 904.00 0.085 0.065 -0.387023123109247 Down 0.0544181746136574 CG30286 CG30286, isoform C K01312|1|1e-17|89.7|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|1e-13|75.9|dme:Dmel_CG4920| [EC:3.4.21.-];K01344|4|4e-12|71.2|rno:25268|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 39259 2494.52 10.865 11.86 0.126415835364721 Up 0.210903447364945 wls wntless, isoform B - GO:0000139//Golgi membrane;GO:0030672//synaptic vesicle membrane;GO:0016021//integral to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0044459//plasma membrane part;GO:0010008//endosome membrane;GO:0000139//Golgi membrane;GO:0030672//synaptic vesicle membrane;GO:0016021//integral to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0044459//plasma membrane part;GO:0010008//endosome membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0006886//intracellular protein transport;GO:0048592//eye morphogenesis;GO:0048522//positive regulation of cellular process;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0046903//secretion;GO:0016055//Wnt receptor signaling pathway;GO:0007365//periodic partitioning;GO:0006886//intracellular protein transport;GO:0048592//eye morphogenesis;GO:0048522//positive regulation of cellular process;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0046903//secretion 40123 4503.93 33.9 10.52 -1.6881505687314 Down 0.743759080702681 Cpr76Bd cuticular protein 76Bd, isoform D K03006|1|4e-07|58.2|cqu:CpipJ_CPIJ016666|DNA-directed RNA polymerase II subunit A [EC:2.7.7.6] - GO:0005198//structural molecule activity - 36242 2033.00 18.38 19.275 0.0685940935133618 Up 0.1547681944261 Egm enigma K00257|1|1e-51|204|xla:446728| [EC:1.3.99.-] - GO:0030554//adenyl nucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity GO:0008152//metabolic process;GO:0006950//response to stress 40738 528.00 0.47 1.33 1.50069358382355 Up 0.343349623563598 Obp83b Odorant-binding protein 83b - GO:0044421//extracellular region part GO:0005488//binding GO:0051234//establishment of localization 43072 2104.00 13.655 0.43 -4.98894884406319 Down 0.835688812574297 tobi target of brain insulin K01187|1|0.0|1305|dme:Dmel_CG11909|alpha-glucosidase [EC:3.2.1.20];K05546|2|3e-21|103|smm:Smp_018760|alpha 1,3-glucosidase [EC:3.2.1.84];K12317|5|3e-20|100|mdo:100010022|neutral alpha-glucosidase C [EC:3.2.1.20] - GO:0016798//hydrolase activity, acting on glycosyl bonds GO:0044238//primary metabolic process 14462901 320.00 1.13 1.63 0.52854919181589 Up 0.217870822876767 CG43702 CG43702, isoform B - - - - 19835601 310.00 0.145 0.165 0.186413124230881 Up 0.0514463082816008 31012 4827.90 11.705 10.995 -0.0902773302570446 Down 0.161009113723418 su(s) suppressor of sable, isoform C - - - - 41677 2520.42 21.695 25.22 0.217205689511477 Up 0.374785365209351 f-cup flyers-cup, isoform I K12796|1|3e-28|127|xtr:780049|erbb2-interacting protein - - - 45780 969.00 0.01 2.9 8.17990909001493 Up 0.739037115308414 Prosalpha1 proteasome alpha1 subunit, isoform B K02730|1|2e-136|484|dme:Dmel_CG30382|20S proteasome subunit alpha 1 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 37305 963.00 16.15 11.665 -0.469347857597088 Down 0.512845066701889 MED8 mediator complex subunit 8 K00922|1|6e-17|88.2|cbr:CBG02868|phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153] - - - 50316 366.00 17.44 14.89 -0.228056286194826 Down 0.355138026680756 CG15213 CG15213 - - - - 40821 754.00 0.06 0.065 0.115477217419936 Up 0.0441487253995509 Ccp84Ae Ccp84Ae - - GO:0005198//structural molecule activity - 42283 1661.00 6.575 9.235 0.490121066802773 Up 0.451987848368776 gatA glutamyl-tRNA amidotransferase subunit A K02433|1|1e-82|307|cel:Y41D4A.6|aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7];K01426|2|2e-30|134|bfo:BRAFLDRAFT_94568|amidase [EC:3.5.1.4];K01175|4|2e-09|64.3|mdo:100023944| [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0051276//chromosome organization;GO:0007292//female gamete generation;GO:0010467//gene expression 42382 5940.00 0.065 0.165 1.34395440121736 Up 0.109463743230749 CG31213 CG31213, isoform C K05643|1|3e-93|344|spu:586285|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 19835180 503.00 3.375 4.755 0.49455783892237 Up 0.352496367718928 40857 1016.00 15.285 12.975 -0.236382013641727 Down 0.350713247919694 CG2656 CG2656 K06883|1|1e-163|575|dme:Dmel_CG2656| - GO:0005488//binding - 318109 1144.00 1.14 1.14 0 - 0.0382380134724607 CG32603 CG32603 K10955|1|1e-10|67.8|hsa:4583|intestinal mucin-2 - - - 36769 2553.42 29.4 22.49 -0.38653249394591 Down 0.527077004358737 casp caspar, isoform C K04649|1|3e-07|57.8|cel:C28G1.1|ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:6.3.2.19] - - - 43746 2331.00 6.115 5.585 -0.130795218044072 Down 0.162032756571127 CG2135 CG2135 K01195|1|0.0|1389|dme:Dmel_CG2135|beta-glucuronidase [EC:3.2.1.31] - GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding GO:0044238//primary metabolic process 41483 2386.00 1.755 1.615 -0.119936865610636 Down 0.0851935015189539 Su(var)3-9 suppressor of variegation 3-9 K11419|1|0.0|1156|dme:Dmel_CG6476|histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43] - - - 39234 645.00 19.825 18.565 -0.0947355507366005 Down 0.191289129573372 blos2 biogenesis of lysosome-related organelles complex 1, subunit 2 - - - - 33310 802.00 0.305 0.23 -0.407175381505873 Down 0.0821555937128517 CG14342 CG14342 - - - - 33112 2367.00 11.35 12.29 0.114792618194384 Up 0.191091005151235 pen penguin - GO:0015630//microtubule cytoskeleton;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0008565//protein transporter activity;GO:0003676//nucleic acid binding GO:0009629//response to gravity;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0006606//protein import into nucleus;GO:0007293//germarium-derived egg chamber formation 19835009 694.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 318860 902.00 3.02 1.32 -1.19401061996663 Down 0.446374323074891 CG31627 CG31627 - - - - 40435 499.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 CG14563 CG14563 - - - - 35473 832.45 293.785 153.7 -0.934643571988519 Down 0.727050587769119 TpnC41C troponin C at 41C, isoform B K02183|1|3e-33|141|smm:Smp_026560.2|calmodulin - GO:0046872//metal ion binding - 3885583 956.21 0.775 1.505 0.957495271485464 Up 0.295370492669396 CG34041 CG34041, isoform F K00472|1|1e-28|127|dya:Dyak_GE23379|prolyl 4-hydroxylase [EC:1.14.11.2] - GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen - 39934 4684.07 4.665 6.205 0.411554129278598 Up 0.355600316999075 CG7692 CG7692, isoform C - - - - 42249 3934.04 51.4 64.935 0.33722794185227 Up 0.537676660943072 Cha choline acetyltransferase, isoform B K00623|1|0.0|1414|dme:Dmel_CG12345|choline O-acetyltransferase [EC:2.3.1.6] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 34125 1105.00 1.93 1.26 -0.615177113768164 Down 0.259080702681284 CG8292 CG8292 - - - - 32273 6242.69 17.835 20.11 0.17320186583854 Up 0.30422005019152 sno strawberry notch, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0032559;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0042675//compound eye cone cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006508//proteolysis;GO:0042675//compound eye cone cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006508//proteolysis 19835829 1024.00 0.59 0.8 0.439285045525521 Up 0.133403777572315 37809 1340.00 13.175 15.83 0.264858293612604 Up 0.376139215427288 CG3803 CG3803 K02259|1|0.0|730|dme:Dmel_CG3803|cytochrome c oxidase subunit XV assembly protein GO:0019866//organelle inner membrane - GO:0065003 40339 1795.57 30.725 34.265 0.157322676401275 Up 0.321159688284243 CG10512 CG10512, isoform D - - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 43716 3762.00 0.23 0.06 -1.93859945533586 Down 0.149484876502444 nyo nyobe, isoform D - - - - 318698 649.00 15.475 16.93 0.129642563794015 Up 0.238706907938185 CG31360 CG31360 - - - - 14462570 1351.00 1.665 0.925 -0.84799690655495 Down 0.290615506538106 48239 1094.00 1.3 1.015 -0.357031895843278 Down 0.150508519350152 ImpE3 Ecdysone-inducible gene E3 - GO:0044425//membrane part - GO:0007560//imaginal disc morphogenesis 318834 914.00 0.01 0.24 4.58496250072116 Up 0.234975564654603 CG31600 CG31600, isoform B - GO:0031224//intrinsic to membrane - - 46078 2535.89 30.935 28.93 -0.0966737106840374 Down 0.223781534803857 vlc vulcan, isoform I K08111|1|5e-11|70.1|cfa:485518|glypican 5 - GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0007478//leg disc morphogenesis;GO:0007154//cell communication;GO:0019538//protein metabolic process;GO:0007478//leg disc morphogenesis;GO:0007154//cell communication;GO:0019538//protein metabolic process;GO:0007478//leg disc morphogenesis;GO:0007154//cell communication;GO:0019538//protein metabolic process;GO:0007478//leg disc morphogenesis;GO:0007154//cell communication;GO:0019538//protein metabolic process;GO:0007478//leg disc morphogenesis;GO:0007154//cell communication;GO:0019538//protein metabolic process;GO:0007478//leg disc morphogenesis;GO:0007154//cell communication 38685 860.00 0.01 5.305 9.05120894091477 Up 0.839420155857879 Jon65Ai jonah 65Ai, isoform B K01310|1|3e-89|328|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|2e-78|292|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39985 1021.00 26.475 31.825 0.265529829909021 Up 0.441024963677189 CG5577 CG5577 K01101|1|5e-120|430|dwi:Dwil_GK10443|4-nitrophenyl phosphatase [EC:3.1.3.41] - GO:0042578//phosphoric ester hydrolase activity - 40198 2308.00 1.875 2.55 0.443606651475615 Up 0.244848765024435 Ir76b ionotropic receptor 76b K05206|1|3e-24|114|tgu:100228875|glutamate receptor, ionotropic, delta 1 GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 41590 1880.00 0.31 0.58 0.903784684740697 Up 0.172632413155462 CG7091 CG7091 K08193|1|4e-43|176|dme:Dmel_CG3036|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|3|1e-42|174|bfo:BRAFLDRAFT_274979|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - - 42172 1594.65 0.83 0.62 -0.420843120960049 Down 0.132380134724607 CG7208 CG7208, isoform B - - - - 37227 1718.00 3.64 3.845 0.0790451477631303 Up 0.0920618148197068 CG11257 CG11257 K00326|1|1e-69|264|dre:553685|cytochrome-b5 reductase [EC:1.6.2.2] - - - 41894 4228.00 23.335 89.09 1.93276803672278 Up 0.776614714040417 CG18522 CG18522 K00106|1|9e-145|515|tad:TRIADDRAFT_26553|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] - - - 19836020 593.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 31067 1603.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG11381 CG11381 - - - - 43502 1250.00 24.875 21.64 -0.200996026491558 Down 0.353850217936864 CG7601 CG7601 K11166|1|0.0|639|dme:Dmel_CG7601|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] GO:0016020//membrane;GO:0005777//peroxisome GO:0003824//catalytic activity GO:0008152//metabolic process 35818 927.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 Lcp2 larval cuticle protein 2, isoform B - - GO:0042302//structural constituent of cuticle - 38997 4338.19 4.065 3.76 -0.11252269039739 Down 0.117487782327302 CG6511 CG6511, isoform B - - - - 40274 1665.00 0.38 0.545 0.520256811333341 Up 0.1232664113063 CG18281 CG18281 K08214|1|2e-06|54.3|bta:504885|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18 GO:0031224//intrinsic to membrane GO:0008493//tetracycline transporter activity GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus 3772489 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33812 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 34403 4096.14 17.65 18.735 0.0860677941705709 Up 0.184024567428345 Cand1 Cullin-associated and neddylation-dissociated 1, isoform B - - - - 14462883 1042.00 0.115 0.13 0.176877762084079 Up 0.0511161009113723 33952 2178.82 159.295 125.5 -0.344013619646293 Down 0.559239202218993 nrv1 nervana 1, isoform B K01540|1|0.0|651|dme:Dmel_CG9258|sodium/potassium-transporting ATPase subunit beta GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0008556//potassium-transporting ATPase activity GO:0009206;GO:0030001//metal ion transport 33274 2605.00 3.1 12 1.95269428522164 Up 0.70122837141725 Lsp1beta larval serum protein 1 beta, isoform B K00505|1|8e-37|155|dme:Dmel_CG42639|tyrosinase [EC:1.14.18.1] GO:0044444//cytoplasmic part GO:0022892 GO:0051234//establishment of localization 19834766 439.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 32778 4117.00 5.29 4.34 -0.285572679669547 Down 0.264529124290054 CG6847 CG6847, isoform B K01046|1|0.0|1701|dme:Dmel_CG6847|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 40429 1065.00 4.935 5.515 0.160310801134985 Up 0.178708228767666 CycH cyclin H K06634|1|0.0|655|dme:Dmel_CG7405|cyclin H GO:0005667//transcription factor complex GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 35679 2803.00 2.205 2.4 0.122255750050998 Up 0.0991942940166425 dpa disc proliferation abnormal, isoform B K02212|1|0.0|1715|dme:Dmel_CG1616|minichromosome maintenance protein 4 (cell division control protein 54) GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0006261//DNA-dependent DNA replication 41531 920.00 144.11 93.86 -0.618588084189599 Down 0.669891691982565 Pros25 proteasome alpha2 subunit K02726|1|1e-132|472|dsi:Dsim_GD18834|20S proteasome subunit alpha 2 [EC:3.4.25.1] - - - 19835986 201.00 0.25 0.01 -4.64385618977472 Down 0.24085325584467 19835118 781.00 0.105 0.06 -0.807354922057604 Down 0.07657508915599 32988 3638.00 14.495 18.43 0.346500737569316 Up 0.462059173160745 CG14234 CG14234 - - - - 34894 2505.23 13.095 11.66 -0.1674482711501 Down 0.266015057456082 yuri yuri gagarin, isoform Q K10352|1|2e-08|61.6|rno:24582|myosin heavy chain GO:0044430//cytoskeletal part;GO:0044430//cytoskeletal part;GO:0044430//cytoskeletal part;GO:0044430//cytoskeletal part;GO:0044430//cytoskeletal part;GO:0044430//cytoskeletal part;GO:0044430//cytoskeletal part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction;GO:0031023//microtubule organizing center organization;GO:0003006//developmental process involved in reproduction 19835000 1229.00 28.81 22.28 -0.370820427819839 Down 0.515222559767534 39420 1736.40 15.07 16.65 0.1438427603608 Up 0.252410513802668 CG10616 CG10616, isoform C - - - - 33057 663.00 0.975 2.33 1.25685583090467 Up 0.410645885616167 CG1835 CG1835, isoform C - - - - 246552 2147.00 38.105 21.465 -0.827994142568575 Down 0.671608770307753 CG30344 CG30344 - GO:0044464//cell part - GO:0006810//transport 39885 1450.00 2.31 4.12 0.834751485767161 Up 0.432307489103157 sinah sina homologue K04506|1|0.0|693|dme:Dmel_CG13030|E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity GO:0046532//regulation of photoreceptor cell differentiation;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0001752//compound eye photoreceptor fate commitment 35620 1116.00 521.52 668.73 0.358701259383056 Up 0.583014132875446 Tsp42Ej tetraspanin 42Ej K06497|1|2e-07|57.0|dan:Dana_GF13154|CD63 antigen GO:0031224//intrinsic to membrane - - 37246 1923.00 11.82 11.925 0.0127592307153414 Up 0.0555739004094571 Rep Rab escort protein - - - - 12798099 611.00 0.825 2.155 1.38522184484328 Up 0.413980980055475 3771723 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33836 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 37136 691.00 25.555 30.135 0.237834473454238 Up 0.407013604543653 mRpS28 mitochondrial ribosomal protein S28 - - - - 14462784 371.00 1.305 0.675 -0.951090399519054 Down 0.274138158763704 34335 2623.00 0.075 0.085 0.180572245641821 Up 0.045667679302602 CG13127 CG13127 - - - - 59141 1567.00 0.075 0.03 -1.32192809488736 Down 0.0800752872804121 CG18745 CG18745 - - - - 35642 2341.00 0.285 0.465 0.70626879694329 Up 0.132049927354379 CG33140 CG33140 - - - - 50395 636.13 21.245 24.265 0.191753516450912 Up 0.34140140007925 CG32736 CG32736, isoform B - - - - 19835675 1050.00 1.395 0.01 -7.12412131182919 Down 0.577796856425835 40492 1932.79 9.95 9.82 -0.018973501116318 Down 0.0624091929731872 CG11241 CG11241, isoform B K00827|1|0.0|967|dme:Dmel_CG11241|alanine--glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40] - GO:0048037//cofactor binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0048037//cofactor binding;GO:0016769//transferase activity, transferring nitrogenous groups - 40453 8353.00 12.6 14.1 0.162271428898877 Up 0.263505481442346 olf413 olf413, isoform C K00503|1|0.0|1246|dpo:Dpse_GA11749|dopamine beta-monooxygenase [EC:1.14.17.1] - GO:0046914//transition metal ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0005975//carbohydrate metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0006547//histidine metabolic process 34185 1478.00 10.875 11.305 0.0559455911280758 Up 0.11689340906089 CG13089 phosphatidylinositol glycan anchor biosynthesis, class U ortholog K05293|1|0.0|770|dme:Dmel_CG13089|phosphatidylinositol glycan, class U GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane - GO:0006497//protein lipidation 31405 2408.13 342.56 344.78 0.00931938815684348 Up 0.0701360454365342 ctp cut up, isoform E K10418|1|3e-46|186|api:100161925|dynein light chain LC8-type GO:0030286//dynein complex;GO:0030286//dynein complex;GO:0030286//dynein complex GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0016887//ATPase activity;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0016887//ATPase activity;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0016887//ATPase activity GO:0044248//cellular catabolic process;GO:0007472//wing disc morphogenesis;GO:0007015//actin filament organization;GO:0048232//male gamete generation;GO:0007017//microtubule-based process;GO:0006997//nucleus organization;GO:0048102//autophagic cell death;GO:0003006//developmental process involved in reproduction;GO:0044248//cellular catabolic process;GO:0007472//wing disc morphogenesis;GO:0007015//actin filament organization;GO:0048232//male gamete generation;GO:0007017//microtubule-based process;GO:0006997//nucleus organization;GO:0048102//autophagic cell death;GO:0003006//developmental process involved in reproduction;GO:0044248//cellular catabolic process;GO:0007472//wing disc morphogenesis;GO:0007015//actin filament organization;GO:0048232//male gamete generation;GO:0007017//microtubule-based process;GO:0006997//nucleus organization;GO:0048102//autophagic cell death;GO:0003006//developmental process involved in reproduction 39497 762.00 0.01 0.245 4.61470984411521 Up 0.239499405626734 CG14111 CG14111 - - - - 33947 3076.00 0.68 0.765 0.169925001442313 Up 0.0781600845330868 TTLL3A tubulin tyrosine ligase-like 3A K05755|1|6e-81|302|ecb:100058358|actin related protein 2/3 complex, subunit 4;K06047|4|6e-23|110|tad:TRIADDRAFT_52733|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity GO:0006464//cellular protein modification process 40489 1801.12 1.275 1.595 0.323059176906011 Up 0.158631620657773 mael maelstrom, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding GO:0060147//regulation of posttranscriptional gene silencing;GO:0007097//nuclear migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0019827//stem cell maintenance;GO:0044087;GO:0006996//organelle organization;GO:0034660//ncRNA metabolic process;GO:0048232//male gamete generation;GO:0022403;GO:0007316//pole plasm RNA localization;GO:0060147//regulation of posttranscriptional gene silencing;GO:0007097//nuclear migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0019827//stem cell maintenance;GO:0044087;GO:0006996//organelle organization;GO:0034660//ncRNA metabolic process;GO:0048232//male gamete generation;GO:0022403;GO:0007316//pole plasm RNA localization;GO:0060147//regulation of posttranscriptional gene silencing;GO:0007097//nuclear migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0019827//stem cell maintenance;GO:0044087;GO:0006996//organelle organization;GO:0034660//ncRNA metabolic process;GO:0048232//male gamete generation;GO:0022403;GO:0007316//pole plasm RNA localization 33017 1883.00 12.43 12.52 0.0104082658801334 Up 0.053625676925109 CG9581 CG9581 K01262|1|0.0|1107|dme:Dmel_CG9581|X-Pro aminopeptidase [EC:3.4.11.9] - GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 117343 1173.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 Gr59d gustatory receptor 59d K08471|1|1e-61|236|dme:Dmel_CG30186|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 12797930 1092.00 0.13 0.25 0.943416471633632 Up 0.113888521991811 CG43174 CG43174 - - - - 37111 751.00 58.595 53.44 -0.132857554737195 Down 0.29784704794611 GstE6 glutathione S transferase E6 K00799|1|2e-123|441|dme:Dmel_CG17530|glutathione S-transferase [EC:2.5.1.18] - - - 38989 2483.00 0.545 0.51 -0.0957589828054305 Down 0.0512812045964866 Cdc6 Cdc6 K02213|1|0.0|1187|dme:Dmel_CG5971|cell division control protein 6 GO:0043231//intracellular membrane-bounded organelle;GO:0032993//protein-DNA complex GO:0016462//pyrophosphatase activity;GO:0032559 GO:0006261//DNA-dependent DNA replication 12798269 535.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 3772575 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33884 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 39225 457.00 0.465 1.1 1.24220090241663 Up 0.286421872936204 Cpr67Fb cuticular protein 67Fb - - GO:0005198//structural molecule activity - 35032 1553.36 1.295 1.465 0.177948566735694 Up 0.100515123497556 CG6304 CG6304, isoform B K04514|1|4e-39|162|dya:Dyak_GE15957|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - - - 37341 656.00 4.55 5.99 0.396689457702727 Up 0.344901598203672 CG11159 CG11159 K01185|1|9e-78|289|dme:Dmel_CG11159|lysozyme [EC:3.2.1.17];K13915|2|1e-29|129|aag:AaeL_AAEL003723|lysozyme C [EC:3.2.1.17] - - - 117407 1397.00 0.17 0.095 -0.839535327806754 Down 0.0879012019548276 Tsp68C tetraspanin 68C, isoform C K06509|1|2e-07|57.0|dre:324098|kangai 1;K06497|2|2e-07|57.0|xla:398555|CD63 antigen;K06537|3|2e-06|53.1|spu:589286|CD151 antigen GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0048534;GO:0048534 32059 848.24 4.77 6.57 0.461904104316818 Up 0.388720116232994 CG1394 CG1394, isoform B K04611|1|4e-06|52.0|dya:Dyak_GE22975|glutamate receptor, metabotropic, invertebrate - - - 39768 950.00 71.575 61.135 -0.227457200735725 Down 0.437954035134064 SsRbeta signal sequence receptor beta K13250|1|9e-105|379|dme:Dmel_CG5474|translocon-associated protein subunit beta GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0004871//signal transducer activity;GO:0042277//peptide binding GO:0035437//maintenance of protein localization in endoplasmic reticulum 42873 1010.04 112.97 55.36 -1.02902385731877 Down 0.728140272090873 CG13606 CG13606, isoform D - - - - 35977 9178.09 50.765 67.635 0.413935839075605 Up 0.579414872539955 brp bruchpilot, isoform M K12478|1|2e-38|162|bta:516259|early endosome antigen 1;K10352|3|9e-37|157|gga:396211|myosin heavy chain - - - 2768875 1060.00 31.2 0.16 -7.60733031374961 Down 0.94231277242108 CG33502 CG33502 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0051540;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0031163 38147 1439.00 26.555 25.13 -0.0795728582121695 Down 0.184354774798574 CG9149 CG9149 K00626|1|0.0|719|dme:Dmel_CG9149|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 40564 1687.00 10.625 9.57 -0.150872011426401 Down 0.226456214502708 CG1074 CG1074 K00599|1|7e-96|351|hsa:60487| [EC:2.1.1.-] - GO:0005488//binding;GO:0016741 GO:0006730//one-carbon metabolic process 38469 9075.00 17.625 20.035 0.18489925225728 Up 0.316668868049135 scrt scratch, isoform B K09219|1|1e-74|281|dre:564658|scratch GO:0044464//cell part GO:0046914//transition metal ion binding GO:0048812//neuron projection morphogenesis 41432 641.25 1010.39 918.25 -0.137953369643392 Down 0.34255712587505 CoVa cytochrome c oxidase subunit Va, isoform C K02264|1|2e-80|298|dya:Dyak_GE24204|cytochrome c oxidase subunit Va [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity GO:0051726//regulation of cell cycle;GO:0022904//respiratory electron transport chain;GO:0051726//regulation of cell cycle;GO:0022904//respiratory electron transport chain 41735 956.00 0.29 0.275 -0.0766212816029123 Down 0.0426627922335227 CG14841 CG14841 - - - - 35321 939.00 3.755 5.745 0.613493985131842 Up 0.425307092854313 CG17470 CG17470 - - - - 246501 694.00 1.29 2.9 1.16868183459168 Up 0.435444459120328 CG30178 CG30178 K05760|1|1e-34|145|isc:IscW_ISCW009899|paxillin - GO:0046914//transition metal ion binding - 5740636 588.00 10.095 5.435 -0.893288970304164 Down 0.579150706643772 CG34309 CG34309 - - - - 8673982 692.36 0.295 0.39 0.402759169500407 Up 0.0941421212521464 CG43127 CG43127, isoform D - - - - 14462854 1354.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 33862 2078.00 12.52 12.085 -0.0510170891670355 Down 0.110718531237617 CG9175 CG9175, isoform B K14003|1|0.0|865|dme:Dmel_CG9175|prolactin regulatory element-binding protein - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 38083 1480.00 1.045 1.32 0.337034987277571 Up 0.148956544710078 CG3344 CG3344 K09646|1|0.0|887|dme:Dmel_CG3344|serine carboxypeptidase 1 [EC:3.4.16.-] - GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process 12798074 372.00 0.595 1.265 1.08817581138637 Up 0.28985602958658 39806 606.00 1.03 0.375 -1.45768183668734 Down 0.301281204596487 CG13058 CG13058 - - - - 31271 2352.00 15.385 24.845 0.691431098216565 Up 0.621978602562409 w white K05679|1|5e-74|279|tgu:100222171|ATP-binding cassette, subfamily G (WHITE), member 1 - - - 36697 2461.93 44.645 51.52 0.206633983148016 Up 0.403249240523049 mus210 mutagen-sensitive 210, isoform D K10838|1|0.0|2048|dme:Dmel_CG8153|xeroderma pigmentosum group C-complementing protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0003677//DNA binding GO:0006281//DNA repair;GO:0006281//DNA repair 36678 5344.14 49.32 57.935 0.232262380441089 Up 0.431052701096288 chn charlatan, isoform I K10495|1|1e-07|60.1|bta:541221|zinc finger and BTB domain-containing protein 8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity;GO:0003677//DNA binding GO:0009996//negative regulation of cell fate specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001745//compound eye morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0009996//negative regulation of cell fate specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001745//compound eye morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0009996//negative regulation of cell fate specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001745//compound eye morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0009996//negative regulation of cell fate specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001745//compound eye morphogenesis;GO:0009792//embryo development ending in birth or egg hatching 34878 5642.00 18.4 21.49 0.223959716483409 Up 0.365473517368908 GABA-B-R1 metabotropic GABA-B receptor subtype 1, isoform C K04615|1|0.0|1651|dme:Dmel_CG15274|gamma-aminobutyric acid (GABA) B receptor 1 GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 36145 2776.30 11.495 8.825 -0.381338282559638 Down 0.42864218729362 CG12344 CG12344, isoform D K05194|1|2e-44|181|bta:537660|glycine receptor alpha-2 GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0005237//inhibitory extracellular ligand-gated ion channel activity GO:0006810//transport 10178925 299.00 92.065 34.41 -1.41982490459641 Down 0.752377493065645 5740699 720.00 4.28 3.22 -0.41055010828653 Down 0.301050059437327 CG34174 CG34174 - - - - 33468 560.00 34.985 41.13 0.233454580185626 Up 0.416490556069211 Taf10b TBP-associated factor 10b K03134|1|7e-67|253|dme:Dmel_CG3069|transcription initiation factor TFIID subunit D8 GO:0005667//transcription factor complex GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 40038 1164.00 0.2 0.34 0.765534746362977 Up 0.118544445912033 CG6893 CG6893 K13577|1|2e-46|186|aga:AgaP_AGAP003074|mitochondrial dicarboxylate carrier GO:0031224//intrinsic to membrane - GO:0006810//transport 5740507 1281.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 CG34259 CG34259 - - - - 50470 538.00 2.265 1.655 -0.452679833239017 Down 0.234678378021397 CG12617 CG12617, isoform C - - - - 41324 983.00 0.83 1.275 0.619314005511933 Up 0.207733456610752 CG6629 CG6629 K00236|1|3e-113|407|dme:Dmel_CG6629|succinate dehydrogenase (ubiquinone) cytochrome b subunit [EC:1.3.5.1] GO:0005746//mitochondrial respiratory chain;GO:0044459//plasma membrane part GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0043648//dicarboxylic acid metabolic process;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain;GO:0009060//aerobic respiration;GO:0006950//response to stress 3772427 1336.00 0.25 0.67 1.42223300068305 Up 0.237452119931317 primo-2 primo-2 K01078|1|2e-90|333|dme:Dmel_CG33747|acid phosphatase [EC:3.1.3.2];K01104|1|2e-90|333|dme:Dmel_CG33747|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044424//intracellular part GO:0004725//protein tyrosine phosphatase activity GO:0006464//cellular protein modification process 14462859 479.00 9.425 4.245 -1.15072806460299 Down 0.612534671773874 CG43986 CG43986 - - - - 39604 929.00 1.015 0.89 -0.189602486218778 Down 0.0880993263769647 CG13471 CG13471 - - GO:0017111//nucleoside-triphosphatase activity - 40506 1445.65 291.685 254.51 -0.196688854446925 Down 0.425901466120724 Arf79F ADP ribosylation factor at 79F, isoform J K07977|1|3e-101|369|dpo:Dpse_GA21036|Arf/Sar family, other;K07937|4|1e-97|357|xtr:394614|ADP-ribosylation factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0001505//regulation of neurotransmitter levels;GO:0019915//lipid storage;GO:0048200;GO:0006897//endocytosis;GO:0006464//cellular protein modification process 35056 2164.16 16.53 16.655 0.0108686293820373 Up 0.0563994188350284 CG6453 CG6453, isoform B K08288|1|0.0|905|dme:Dmel_CG6453|protein kinase C substrate 80K-H - GO:0046872//metal ion binding;GO:0015926//glucosidase activity - 50216 447.00 0.285 0.01 -4.83289001416474 Down 0.263802668075551 CG15919 CG15919 - - - - 36750 1773.08 147.105 165.835 0.172902240649788 Up 0.379243164707436 Mlf Myelodysplasia/myeloid leukemia factor, isoform H - GO:0044444//cytoplasmic part;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle - - 3346203 564.00 3.865 3.23 -0.258934249230922 Down 0.209483555672963 Acp53C14c accessory gland protein 53C14c, isoform B - - - - 246556 1365.00 0.87 1.275 0.55140994101013 Up 0.194558182538634 CG30350 CG30350 - - GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process 36605 4357.65 6.345 14.95 1.23645341524436 Up 0.6658961828028 CG17386 CG17386, isoform B K11090|1|2e-07|59.3|tgu:100190598|lupus La protein - GO:0005488//binding - 41266 4402.66 7.725 9.405 0.283893010731459 Up 0.33387267203804 Rfx Rfx, isoform J K09173|1|0.0|1123|dvi:Dvir_GJ23659|regulatory factor X 1/2/3 GO:0044464//cell part;GO:0044464//cell part GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity GO:0010468//regulation of gene expression;GO:0019538//protein metabolic process;GO:0048812//neuron projection morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0019538//protein metabolic process;GO:0048812//neuron projection morphogenesis;GO:0006350 33792 1804.00 1.09 1.49 0.450984195685236 Up 0.188746532822613 CG18266 CG18266 - - - - 31155 6716.00 21.03 25.285 0.265832928395505 Up 0.42411834632149 Rbcn-3B Rabconnectin-3B, isoform B K03130|1|1e-06|57.0|dgr:Dgri_GH16552|transcription initiation factor TFIID subunit D4;K10266|2|1e-06|57.0|bta:511953|F-box and WD-40 domain protein 10;K12862|3|5e-06|55.1|bfo:BRAFLDRAFT_119198|pleiotropic regulator 1 - - - 37973 3047.27 7.92 6.17 -0.360229940930192 Down 0.364912164839519 Dll Distal-less, isoform C K09316|1|3e-144|512|dme:Dmel_CG3629|homeobox protein DLX, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0010468//regulation of gene expression;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0007484//imaginal disc-derived genitalia development;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0006350;GO:0010468//regulation of gene expression;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0007484//imaginal disc-derived genitalia development;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0006350;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0007484//imaginal disc-derived genitalia development;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0035108//limb morphogenesis;GO:0006350 2768900 607.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 Ste:CG33240 Ste:CG33240 K08282|1|2e-95|347|dme:Dmel_CG33236|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 44235 5636.76 17 17.4 0.0335525597110264 Up 0.0926231673490952 bon bonus, isoform F K08883|1|0.0|1787|dya:Dyak_GE25673|tripartite motif-containing protein 33 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis;GO:0006935//chemotaxis;GO:0048812//neuron projection morphogenesis 5740271 1832.00 0.045 0.03 -0.584962500721156 Down 0.047450799101836 Vml vitelline membrane-like K11515|1|9e-12|72.0|xla:398105|inner centromere protein;K11423|2|5e-11|69.7|dgr:Dgri_GH16034|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43] - - - 31631 1923.56 11.565 13.62 0.235961437375881 Up 0.337670056795668 CG4558 CG4558, isoform B - - - - 40869 1472.00 0.565 0.5 -0.176322772640463 Down 0.0718531237617224 CG14607 CG14607 - - GO:0030247//polysaccharide binding GO:0006022 36969 2022.00 0.21 0.415 0.982722008568164 Up 0.147635715229164 CG30103 CG30103 K01081|1|8e-140|497|dpo:Dpse_GA15652|5'-nucleotidase [EC:3.1.3.5] - - - 34949 905.00 0.135 0.29 1.1030934929641 Up 0.130960243032624 CG4892 CG4892 - - - - 38120 818.00 15.59 13.745 -0.181714021184831 Down 0.294181746136574 CG13912 CG13912 - - - - 33706 827.00 6.09 6.875 0.174917485393052 Up 0.210044908202351 Jon25Biii jonah 25Biii K01310|1|1e-77|289|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|2e-77|288|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38717 2685.00 12.14 11.585 -0.0675103773908602 Down 0.133469819046361 D19B D19B K09228|1|1e-49|198|hsa:7652|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 42734 3473.00 10.68 9.615 -0.151552884347657 Down 0.227479857350416 Rassf Ras association family member K09853|1|9e-36|152|ssc:100152580|Ras association domain-containing protein 4;K09851|3|2e-34|148|xtr:548420|Ras association domain-containing protein 2 - GO:0046914//transition metal ion binding GO:0035264//multicellular organism growth;GO:0010212//response to ionizing radiation;GO:0007165//signal transduction 34451 1371.00 0.92 0.835 -0.139857663582961 Down 0.0730748910315678 CG18301 CG18301 K01046|1|2e-90|333|dme:Dmel_CG7329|triacylglycerol lipase [EC:3.1.1.3];K01066|4|1e-73|276|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|5|5e-73|275|ecb:100071626|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - - GO:0044238//primary metabolic process 38376 4286.83 31.74 33.21 0.0653155946675266 Up 0.172896579051644 BtbVII BTB-protein-VII, isoform I K09237|1|9e-37|156|nvi:100122117|Cys2His2 zinc finger developmental/cell cycle regulator, other - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 41960 2357.73 11.24 14.35 0.352408701342124 Up 0.437689869237881 CG5916 CG5916, isoform B K11837|1|7e-12|72.8|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K13136|2|1e-05|52.4|nvi:100114269|gem associated protein 8 - - - 43503 1048.00 24.305 31.155 0.358210582777222 Up 0.513835688812574 CG7598 CG7598 K13617|1|1e-24|113|smm:Smp_149920|protein phosphatase methylesterase 1 [EC:3.1.1.-] GO:0005746//mitochondrial respiratory chain - GO:0006091//generation of precursor metabolites and energy 31953 4946.13 21.905 25.585 0.224038018687091 Up 0.378516708492934 CG34408 CG34408, isoform J - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0009966//regulation of signal transduction;GO:0009966//regulation of signal transduction;GO:0009966//regulation of signal transduction;GO:0009966//regulation of signal transduction 37329 1946.21 13.13 12.585 -0.0611616997319072 Down 0.126931713115837 CG9945 CG9945, isoform B K11801|1|0.0|989|dme:Dmel_CG9945|WD repeat-containing protein 23 - - - 19834788 1103.00 0.505 0.435 -0.215267986903066 Down 0.0736032228239334 43676 1795.95 42.78 42.32 -0.0155968550510185 Down 0.0819904900277374 CG11317 CG11317, isoform B - GO:0044464//cell part GO:0046914//transition metal ion binding - 3771890 8481.00 51.275 56.225 0.132956169297965 Up 0.296988508783516 eys eyes shut, isoform F K02599|1|3e-72|275|spu:575027|Notch GO:0044421//extracellular region part;GO:0016020//membrane - GO:0042051//compound eye photoreceptor development;GO:0009266//response to temperature stimulus 3771929 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 39585 651.00 0.37 0.485 0.390459476558178 Up 0.101703870030379 CG9592 CG9592 - - - - 35248 4694.99 81.895 63.04 -0.377507837763021 Down 0.569541672170123 Tep4 Thioester-containing protein 4, isoform D K06530|1|0.0|1055|dme:Dmel_CG7052|CD109 antigen GO:0044421//extracellular region part GO:0061135;GO:0005488//binding - 40400 1369.88 6.135 7.57 0.303229956322827 Up 0.321159688284243 CG11307 CG11307, isoform D K03844|1|1e-78|293|dya:Dyak_GE23039|alpha-1,2-mannosyltransferase [EC:2.4.1.-] - - GO:0008152//metabolic process;GO:0008152//metabolic process 32594 3558.00 3.665 3.98 0.118955232409837 Up 0.122473913617752 CG13957 CG13957 - - - - 318107 967.00 0.045 0.185 2.03952836418664 Up 0.136804913485669 betaNACtes6 betaNACtes6 K01527|1|2e-08|60.1|dsi:Dsim_GD10924|nascent polypeptide-associated complex subunit beta GO:0043231//intracellular membrane-bounded organelle - GO:0006351//transcription, DNA-dependent 40888 415.00 13.11 18.86 0.524661990453342 Up 0.551314225333509 Mst84Db Male-specific RNA 84Db - - - - 34001 2566.00 7.82 8.43 0.10836402363473 Up 0.162627129837538 CG4497 CG4497, isoform B - - - - 42061 729.00 26.035 31.68 0.28311992868936 Up 0.452318055739004 mRpS11 mitochondrial ribosomal protein S11 - - - - 34759 1198.00 0.26 0.255 -0.0280143761695966 Down 0.0416391493858143 CG16848 CG16848 K00953|1|4e-150|530|dme:Dmel_CG16848|FAD synthetase [EC:2.7.7.2] - GO:0003824//catalytic activity - 45706 1690.12 7.975 7.915 -0.0108951685150506 Down 0.0502575617487782 Cyp4d14 Cyp4d14, isoform B K00517|1|0.0|975|dme:Dmel_CG3540| [EC:1.14.-.-] GO:0042598 GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 19835952 411.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 19835722 757.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 5740569 371.00 0.235 0.16 -0.554588851677637 Down 0.0891890106987188 CG34337 CG34337 - - - - 19835732 559.00 0.15 0.085 -0.819427754358179 Down 0.0821225729758288 318646 1228.00 0.285 0.12 -1.24792751344359 Down 0.142385418042531 CG31253 CG31253 - - - - 317956 457.00 2.06 0.715 -1.52662919040483 Down 0.421674811781799 CG32284 CG32284 - - GO:0030247//polysaccharide binding GO:0006022 38857 793.00 32.33 34.16 0.0794344674944049 Up 0.193270373794743 CG7506 CG7506 - GO:0031224//intrinsic to membrane - - 38423 1636.00 4.495 4.43 -0.0210144169594291 Down 0.0542200501915203 CG12014 CG12014 K01136|1|0.0|1042|dme:Dmel_CG12014|iduronate 2-sulfatase [EC:3.1.6.13] - GO:0016788//hydrolase activity, acting on ester bonds - 41413 2107.00 2.1 3.3 0.652076696579693 Up 0.347378153480386 CG14718 CG14718 K13098|1|2e-21|104|tca:658894|RNA-binding protein FUS GO:0044464//cell part GO:0046914//transition metal ion binding - 38936 1109.56 181.065 207.75 0.198340777788777 Up 0.422995641262713 BI-1 Bax Inhibitor-1, isoform B K06890|1|5e-06|52.4|nve:NEMVE_v1g159748| GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006915//apoptotic process;GO:0006915//apoptotic process 32741 1770.00 21.93 24.355 0.151312171166855 Up 0.291639149385814 CG8289 CG8289, isoform B K11587|1|1e-08|61.6|xtr:394502|chromobox protein 5 GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006325//chromatin organization;GO:0006305 12798477 795.00 0.905 1.215 0.424966616522576 Up 0.163089420155858 CG43068 CG43068 - - - - 45815 1588.53 62.16 39.765 -0.644487332819295 Down 0.656221106855105 Spn27A serpin 27A, isoform B K13963|1|3e-41|169|hsa:6317|serpin B - GO:0004866//endopeptidase inhibitor activity GO:0035006//melanization defense response;GO:0009892//negative regulation of metabolic process;GO:0009798//axis specification;GO:0030162//regulation of proteolysis;GO:0007166//cell surface receptor signaling pathway 19835785 296.00 0.17 0.01 -4.08746284125034 Down 0.187062475234447 2769001 10658.14 22.77 24.665 0.11533099585787 Up 0.245046889446572 zormin zormin, isoform K K00907|1|3e-69|265|spu:581963|myosin-light-chain kinase [EC:2.7.11.18] - - - 19835050 498.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 40541 1468.33 55.495 41.41 -0.422378590373776 Down 0.577631752740721 MP1 melanization protease 1, isoform C K01362|1|4e-105|381|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|3|1e-73|277|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0006582//melanin metabolic process;GO:0019538//protein metabolic process;GO:0006582//melanin metabolic process;GO:0019538//protein metabolic process 318666 877.00 0.85 0.795 -0.0965079808533466 Down 0.061352529388456 CG31294 CG31294 K09553|1|4e-08|58.5|bmy:Bm1_55560|stress-induced-phosphoprotein 1;K04460|2|5e-08|58.2|dmo:Dmoj_GI22745|protein phosphatase 5 [EC:3.1.3.16] - - - 38871 1538.74 266.075 179.715 -0.566122134191094 Down 0.665301809536389 Hn henna, isoform D K00500|1|0.0|924|dsi:Dsim_GD14035|phenylalanine-4-hydroxylase [EC:1.14.16.1] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0031406//carboxylic acid binding;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0031406//carboxylic acid binding GO:0042441//eye pigment metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006909//phagocytosis;GO:0042441//eye pigment metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006909//phagocytosis 34041 1358.00 0.23 0.47 1.03102689562062 Up 0.166391493858143 CG18585 CG18585, isoform B K01290|1|9e-142|503|dme:Dmel_CG7025|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 32939 7720.77 10.655 11.975 0.168495062840839 Up 0.259410910051512 CG14200 CG14200, isoform C - GO:0044464//cell part GO:0046914//transition metal ion binding - 32724 2719.00 2.675 2.51 -0.0918515273377372 Down 0.0858539162594109 B-H1 BarH1, isoform B K09360|1|3e-124|446|dme:Dmel_CG5529|BarH-like - GO:0005488//binding GO:0010468//regulation of gene expression;GO:0001745//compound eye morphogenesis;GO:0048753//pigment granule organization;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007560//imaginal disc morphogenesis;GO:0006350 39814 1148.00 0.135 0.365 1.43493705671655 Up 0.170023774930656 Cpr72Ea cuticular protein 72Ea - - GO:0005198//structural molecule activity - 43780 2506.23 70.765 66.12 -0.0979492626344271 Down 0.247424382512218 CG1674 CG1674, isoform M - - - - 3772271 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33886 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 33270 2949.61 75.835 88.74 0.226720706445711 Up 0.443534539690926 PNUTS PNUTS, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0019208//phosphatase regulator activity;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0019208//phosphatase regulator activity;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0019208//phosphatase regulator activity GO:0006470//protein dephosphorylation;GO:0006909//phagocytosis;GO:0019222//regulation of metabolic process;GO:0006351//transcription, DNA-dependent;GO:0006886//intracellular protein transport;GO:0006470//protein dephosphorylation;GO:0006909//phagocytosis;GO:0019222//regulation of metabolic process;GO:0006351//transcription, DNA-dependent;GO:0006886//intracellular protein transport;GO:0006470//protein dephosphorylation;GO:0006909//phagocytosis;GO:0019222//regulation of metabolic process;GO:0006351//transcription, DNA-dependent;GO:0006886//intracellular protein transport 31540 1948.31 73.155 48.1 -0.60491957909962 Down 0.651829348831066 Tsp5D tetraspanin 5D, isoform C K06537|1|6e-29|129|bta:523328|CD151 antigen - - - 42544 1856.00 1.405 1.6 0.187501774666436 Up 0.109199577334566 C15 C15 K09340|1|6e-69|261|cqu:CpipJ_CPIJ004114|T-cell leukemia homeobox protein GO:0032991//macromolecular complex GO:0003677//DNA binding GO:0007423//sensory organ development;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010468//regulation of gene expression;GO:0007478//leg disc morphogenesis;GO:0006350;GO:0048800//antennal morphogenesis;GO:0008593//regulation of Notch signaling pathway 36959 3130.56 23.37 21.565 -0.115966018048325 Down 0.242339189010699 EDTP Egg-derived tyrosine phosphatase, isoform C K01104|1|0.0|1210|dme:Dmel_CG6542|protein-tyrosine phosphatase [EC:3.1.3.48] - - - 41567 614.00 1.24 1.72 0.472068444315223 Up 0.209417514198917 CG14391 CG14391 - - - - 48316 860.00 57.49 36.045 -0.673511881562481 Down 0.659027869502047 alphaTry alphaTrypsin K01312|1|2e-100|365|dme:Dmel_CG18444|trypsin [EC:3.4.21.4] GO:0005576//extracellular region GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40467 1617.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG11449 CG11449 K11515|1|5e-10|66.2|oaa:100090319|inner centromere protein - - - 12798115 383.00 0.115 0.13 0.176877762084079 Up 0.0511161009113723 19836065 1374.00 0.715 0.49 -0.545161492663181 Down 0.140668339717342 41092 1121.00 1.98 2.97 0.584962500721156 Up 0.310890239070136 Ada adenosine deaminase K01488|1|0.0|672|dme:Dmel_CG11994|adenosine deaminase [EC:3.5.4.4] - GO:0043169//cation binding;GO:0003824//catalytic activity GO:0009127//purine nucleoside monophosphate biosynthetic process 37554 2944.52 23.22 24.415 0.072399805771897 Up 0.1670519085986 Rtf1 Rtf1, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0018024//histone-lysine N-methyltransferase activity GO:0034968//histone lysine methylation;GO:0031062//positive regulation of histone methylation;GO:0008593//regulation of Notch signaling pathway 41477 1861.00 0.165 0.045 -1.87446911791614 Down 0.124058908994849 CG4830 CG4830 K01904|1|1e-46|187|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12];K01896|5|5e-25|116|rno:353317|medium-chain acyl-CoA synthetase [EC:6.2.1.2] - - - 39437 1709.00 6.04 5.28 -0.194010619966625 Down 0.213313961167613 CG4069 CG4069 K10317|1|5e-13|76.3|aag:AaeL_AAEL000867|F-box protein 42 - GO:0005488//binding - 42681 2619.00 7.615 4.025 -0.919855253485313 Down 0.548507462686567 cd cardinal K10789|1|4e-80|299|gga:417467|myeloperoxidase [EC:1.11.1.7];K00431|2|2e-77|290|mdo:100032350|thyroid peroxidase [EC:1.11.1.8] - GO:0005506//iron ion binding;GO:0016209//antioxidant activity GO:0008152//metabolic process;GO:0006950//response to stress 40118 1424.17 24.37 17.35 -0.490170588257717 Down 0.561319508651433 CG9451 CG9451, isoform B K01078|1|0.0|843|dme:Dmel_CG9451|acid phosphatase [EC:3.1.3.2] - GO:0016791//phosphatase activity GO:0006909//phagocytosis 33758 3913.58 6.515 6.6 0.018700845677681 Up 0.0559701492537313 Bub1 Bub1 homologue, isoform C K02178|1|0.0|1692|dme:Dmel_CG14030|checkpoint serine/threonine-protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0000166//nucleotide binding GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006464//cellular protein modification process 43257 1701.56 2.625 2 -0.39231742277876 Down 0.230715889578655 CG14257 CG14257, isoform C - GO:0031224//intrinsic to membrane - GO:0007166//cell surface receptor signaling pathway 34191 1469.45 16.12 10.635 -0.600031710567295 Down 0.562574296658301 CG17834 CG17834, isoform F - - - - 38565 2124.00 14.59 13.29 -0.134638778641717 Down 0.232003698322547 Rpd3 Rpd3 K06067|1|0.0|845|dsi:Dsim_GD13856|histone deacetylase 1/2 [EC:3.5.1.98] GO:0005700//polytene chromosome;GO:0070822//Sin3-type complex;GO:0031519//PcG protein complex GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0003712//transcription cofactor activity GO:0009880//embryonic pattern specification;GO:0006476//protein deacetylation;GO:0016458//gene silencing;GO:0048812//neuron projection morphogenesis;GO:0010259//multicellular organismal aging;GO:0048513//organ development;GO:0022900//electron transport chain;GO:0006350;GO:0007292//female gamete generation;GO:0009060//aerobic respiration 32257 1951.00 21.54 16.98 -0.343181790991169 Down 0.471767269845463 lic licorne K04432|1|0.0|681|dsi:Dsim_GD24803|mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] - GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032559 GO:0007309//oocyte axis specification;GO:0000165//MAPK cascade;GO:0002251;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006464//cellular protein modification process 326270 274.00 1.53 4.005 1.38827058971606 Up 0.521034209483556 MtnD metallothionein D - - GO:0046914//transition metal ion binding - 32001 1211.83 596.295 549.22 -0.118642077068922 Down 0.303856822084269 Atg8a Autophagy-specific gene 8a, isoform C K08341|1|1e-65|250|dme:Dmel_CG32672|GABA(A) receptor-associated protein (autophagy-related protein 8) - GO:0004871//signal transducer activity GO:0010259//multicellular organismal aging 36986 7772.67 8.46 9.02 0.0924697701354314 Up 0.146843217540615 MESR4 misexpression suppressor of ras 4, isoform D K09228|1|1e-15|87.0|rno:367033|KRAB domain-containing zinc finger protein - - - 42808 894.00 199.685 222.31 0.154846881430761 Up 0.351604807819311 CG10219 CG10219 K00237|1|8e-95|346|dme:Dmel_CG10219|succinate dehydrogenase (ubiquinone) membrane anchor subunit [EC:1.3.5.1] GO:0031224//intrinsic to membrane;GO:0005746//mitochondrial respiratory chain GO:0005506//iron ion binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0009060//aerobic respiration 42931 2094.00 7.095 6.785 -0.0644538686416972 Down 0.103420948355567 CG13625 CG13625 K13106|1|0.0|886|dme:Dmel_CG13625|pre-mRNA-splicing factor CWC26 GO:0005681//spliceosomal complex - - 38395 7388.00 6.355 7.995 0.331205908475373 Up 0.347972526746797 CG14967 CG14967 - - - - 36865 2400.78 56.325 49.355 -0.190579161472955 Down 0.383238673887201 Picot picot, isoform D K08193|1|0.0|660|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - - 3355162 950.44 11.2 38.39 1.77723182790198 Up 0.752212389380531 CG40486 CG40486, isoform C K11166|1|4e-14|78.6|mmu:216820|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 41761 663.00 5.805 4.345 -0.417939890051166 Down 0.350383040549465 CG14854 CG14854 - - - - 40623 1630.69 151.745 180.535 0.250629576513387 Up 0.477545898824462 CG2604 CG2604, isoform C - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - - 42891 2159.23 11.66 14.895 0.353260335049034 Up 0.441289129573372 Orct organic cation transporter, isoform B K08202|1|0.0|1064|dme:Dmel_CG6331|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane GO:0008324//cation transmembrane transporter activity GO:0001700//embryonic development via the syncytial blastoderm;GO:0035264//multicellular organism growth;GO:0016049//cell growth;GO:0006812//cation transport;GO:0012501//programmed cell death 37054 910.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 CG5770 CG5770 - - - - 41032 3209.33 2.98 2.58 -0.207941265038907 Down 0.158103288865407 hb hunchback, isoform B K09213|1|0.0|1040|dme:Dmel_CG9786|hunchback GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0035287//head segmentation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050793//regulation of developmental process;GO:0001708//cell fate specification;GO:0009653//anatomical structure morphogenesis;GO:0007424//open tracheal system development;GO:0035272//exocrine system development;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0010468//regulation of gene expression;GO:0035287//head segmentation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050793//regulation of developmental process;GO:0001708//cell fate specification;GO:0009653//anatomical structure morphogenesis;GO:0007424//open tracheal system development;GO:0035272//exocrine system development 42783 1330.00 40.2 44.125 0.134400776979614 Up 0.290252278430855 CG10184 CG10184 K01620|1|0.0|722|dme:Dmel_CG10184|threonine aldolase [EC:4.1.2.5] - GO:0003824//catalytic activity;GO:0048037//cofactor binding GO:0006519 45821 12368.36 22.365 33.175 0.568853707252957 Up 0.610190199445252 Abl Abl tyrosine kinase, isoform J K06619|1|0.0|2448|dme:Dmel_CG4032|proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2] GO:0044448//cell cortex part;GO:0005924//cell-substrate adherens junction;GO:0019898//extrinsic to membrane;GO:0044448//cell cortex part;GO:0005924//cell-substrate adherens junction;GO:0019898//extrinsic to membrane GO:0004713//protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0032559;GO:0046914//transition metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0010004//gastrulation involving germ band extension;GO:0048729//tissue morphogenesis;GO:0030832//regulation of actin filament length;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0008104//protein localization;GO:0006935//chemotaxis;GO:0010608//posttranscriptional regulation of gene expression;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007300//ovarian nurse cell to oocyte transport;GO:0010004//gastrulation involving germ band extension;GO:0048729//tissue morphogenesis;GO:0030832//regulation of actin filament length;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0008104//protein localization;GO:0006935//chemotaxis;GO:0010608//posttranscriptional regulation of gene expression;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007300//ovarian nurse cell to oocyte transport 19834884 433.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 41285 681.00 1.985 2.8 0.496287819802009 Up 0.276680755514463 tomboy20 tomboy20 - GO:0005741//mitochondrial outer membrane GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting 50344 428.00 0.1 0.555 2.47248777146274 Up 0.271694624224013 CG12479 CG12479 - - - - 5740416 560.00 0.22 0.505 1.1987798641145 Up 0.188449346189407 CG34245 CG34245 - - - - 34888 4126.79 11.06 11.23 0.0220065421658945 Up 0.0666688680491349 stc shuttle craft, isoform D K12236|1|0.0|2068|dme:Dmel_CG3647|transcriptional repressor NF-X1 [EC:6.3.2.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048731;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048731 246604 843.00 0.145 0.265 0.869939459435627 Up 0.112567692510897 CG30417 CG30417 K08871|1|2e-45|182|dpo:Dpse_GA15830|bromodomain-containing protein 2;K11721|2|2e-25|115|ame:551826|bromodomain-containing protein 3;K11722|4|4e-24|111|tca:656325|bromodomain-containing protein 4 - - - 32020 4056.93 4.17 6.965 0.740075969156589 Up 0.495509179764892 Ork1 open rectifier K[+] channel 1, isoform D K04915|1|2e-29|132|rno:116489|potassium channel subfamily K member 4;K04924|3|1e-27|126|tgu:100224802|potassium channel subfamily K member 16 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005249//voltage-gated potassium channel activity;GO:0005249//voltage-gated potassium channel activity GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0008016//regulation of heart contraction;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0008016//regulation of heart contraction 33425 1493.00 2.04 2.095 0.0383810917278562 Up 0.0559371285167085 CG9870 CG9870 K05283|1|0.0|786|dse:Dsec_GM18338|phosphatidylinositol glycan, class W [EC:2.3.-.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016740//transferase activity GO:0006497//protein lipidation 19835912 478.00 0.435 0.325 -0.420575682820274 Down 0.0987650244353454 19836183 443.00 0.36 0.01 -5.16992500144231 Down 0.301512349755647 42234 693.00 86.335 55.84 -0.628646601517254 Down 0.662362963941355 CG7695 CG7695 - - - - 40831 1526.00 1.955 1.855 -0.075749420686549 Down 0.0690133403777572 Ama amalgam, isoform C K06772|1|1e-25|117|hsa:4045|limbic system-associated membrane protein GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0009987//cellular process;GO:0009987//cellular process;GO:0009987//cellular process 19834746 1103.00 0.26 0.085 -1.61297687689075 Down 0.152423722097477 33240 2362.00 0.745 0.765 0.0382193222304901 Up 0.0449742438251222 Gsc goosecoid, isoform D K09324|1|4e-67|256|dme:Dmel_CG2851|homeobox protein goosecoid GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 246545 632.00 1.09 1.445 0.406741357723753 Up 0.175406155065381 CG30334 CG30334, isoform B - - - - 44297 3548.91 32.77 23.4 -0.485867143071993 Down 0.582188614449875 ome omega, isoform H K01278|1|0.0|1444|dya:Dyak_GE22026|dipeptidyl-peptidase 4 [EC:3.4.14.5] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 37625 1721.00 0.05 0.085 0.765534746362977 Up 0.0694426099590543 CG9826 CG9826, isoform C K08193|1|2e-74|280|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport;GO:0006810//transport 34819 5386.00 2.08 1.715 -0.27837495196828 Down 0.16137234183067 rk rickets K08399|1|0.0|2239|dme:Dmel_CG8930|leucine-rich repeat-containing G protein-coupled receptor 6 GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway 14462668 1082.00 14.455 17.66 0.288916734171417 Up 0.413089420155858 40049 2491.64 79.82 72.395 -0.14086021861667 Down 0.320730418702945 Indy I'm not dead yet, isoform D - GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity GO:0010883//regulation of lipid storage;GO:0006259//DNA metabolic process;GO:0010259//multicellular organismal aging;GO:0030001//metal ion transport;GO:0010883//regulation of lipid storage;GO:0006259//DNA metabolic process;GO:0010259//multicellular organismal aging;GO:0030001//metal ion transport;GO:0010883//regulation of lipid storage;GO:0006259//DNA metabolic process;GO:0010259//multicellular organismal aging;GO:0030001//metal ion transport;GO:0010883//regulation of lipid storage;GO:0006259//DNA metabolic process;GO:0010259//multicellular organismal aging;GO:0030001//metal ion transport 35765 1302.75 28.135 27.31 -0.0429366492922706 Down 0.119006736230353 CG11191 CG11191, isoform B - - - - 7354424 572.65 62.92 52.48 -0.261750950797603 Down 0.464865935807687 CG42394 CG42394, isoform D - - - - 14462463 707.00 19.175 22.69 0.242830031282042 Up 0.388521991810857 CG44194 CG44194, isoform B - - - - 35629 848.00 3.21 4.275 0.413351122650957 Up 0.302734117025492 Tsp42Er tetraspanin 42Er K06497|1|2e-23|108|dan:Dana_GF13154|CD63 antigen;K06489|5|1e-13|77.0|ecb:100058745|CD53 antigen GO:0031224//intrinsic to membrane - - 37467 1189.00 14.615 12.625 -0.211166441279533 Down 0.319343547747986 Rae1 Rae1 K02180|1|1e-50|200|dre:403012|cell cycle arrest protein BUB3 - GO:0004683//calmodulin-dependent protein kinase activity - 42306 2686.02 75.565 80.555 0.092255973499319 Up 0.23111213842293 vib vibrator, isoform C K01106|1|5e-85|314|gga:771549|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] GO:0005739//mitochondrion;GO:0032155;GO:0005635//nuclear envelope;GO:0016020//membrane GO:0005543//phospholipid binding;GO:0005319//lipid transporter activity GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0000212//meiotic spindle organization;GO:0048610//cellular process involved in reproduction;GO:0051234//establishment of localization;GO:0033206//cytokinesis after meiosis 34749 1965.52 27.16 28.035 0.0457455902215826 Up 0.132908466516973 CG6565 CG6565, isoform C - - - - 38196 2517.17 451.385 618.51 0.454438443673796 Up 0.629474309866596 n-syb neuronal synaptobrevin, isoform K K13504|1|5e-42|172|dwi:Dwil_GK23666|vesicle-associated membrane protein 2 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis 7354472 5569.91 4.85 6.57 0.43790862324784 Up 0.378219521859728 CG42340 CG42340, isoform D K05323|1|4e-11|71.6|cel:C52B9.6|potassium channel subfamily K, invertebrate;K04924|3|4e-11|71.6|tgu:100224802|potassium channel subfamily K member 16;K04923|5|6e-10|67.8|rno:156873|potassium channel subfamily K member 15 GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 41646 1880.20 294.79 294.045 -0.00365062667458535 Down 0.0473187161537445 Droj2 DnaJ-like-2, isoform E K09502|1|0.0|712|dme:Dmel_CG8863|DnaJ homolog subfamily A member 1 - - - 42745 2391.00 0.41 0.835 1.02615228785597 Up 0.226456214502708 fzo fuzzy onions K06030|1|7e-103|375|dpo:Dpse_GA17739| [EC:3.6.5.-] GO:0031224//intrinsic to membrane;GO:0031966//mitochondrial membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0048869//cellular developmental process;GO:0006996//organelle organization;GO:0006944//cellular membrane fusion;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction 45994 5690.00 0.09 0.125 0.473931188332412 Up 0.0679896975300489 fs(1)M3 female sterile (1) M3 - - - - 19835969 1251.00 0.01 0.04 2 Up 0.0694426099590543 32097 4400.06 22.15 20.67 -0.0997683100169329 Down 0.209747721569145 Drak Death-associated protein kinase related, isoform E K08804|1|3e-61|238|ecb:100064585|serine/threonine kinase 17 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 2768948 4825.18 22.805 22.12 -0.0439987846230474 Down 0.115077268524633 CG33275 CG33275, isoform D K08810|1|9e-49|196|ptr:461730|triple functional domain protein [EC:2.7.11.-] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction 39111 3666.31 18.735 18.95 0.0164618707293407 Up 0.0708625016510369 CG42673 CG42673, isoform D K12474|1|1e-11|72.0|gga:419589|low density lipoprotein receptor adapter protein 1 - - - 41833 3634.00 10.625 11.415 0.103468018312275 Up 0.174283450006604 SIDL shal interactor of Di-Leucine motif - - - - 38623 800.49 4.58 1.72 -1.41293903339485 Down 0.544875181614054 CG13285 CG13285, isoform B - - - - 39430 3824.99 53.81 50.175 -0.100905595204795 Down 0.242768458591996 tral trailer hitch, isoform I - GO:0043229//intracellular organelle;GO:0044444//cytoplasmic part - GO:0007010//cytoskeleton organization 39944 1928.00 11.82 13.91 0.234892384364706 Up 0.335292563730022 CG32176 CG32176 - - - - 34502 1722.22 4.84 5.135 0.0853572290436005 Up 0.109232598071589 CG43129 CG43129, isoform E K11848|1|1e-29|131|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15];K11426|2|1e-09|65.1|ssc:100294702|SET and MYND domain-containing protein - - - 59246 600.55 19.365 20.77 0.101049714816301 Up 0.2073702285035 CG18731 CG18731, isoform B - GO:0000794//condensed nuclear chromosome - GO:0007129//synapsis 41291 1020.00 291.625 193.285 -0.593384721542379 Down 0.671080438515388 fau fau - - - - 19836151 496.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 38168 2539.66 10.23 9.005 -0.184007963839053 Down 0.257231541408004 rho rhomboid, isoform B K02857|1|0.0|638|dse:Dsec_GM14413|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral to membrane GO:0004175//endopeptidase activity GO:0051605;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0007424//open tracheal system development;GO:0001742//oenocyte differentiation;GO:0003006//developmental process involved in reproduction;GO:0030534//adult behavior;GO:0035468;GO:0001708//cell fate specification;GO:0051301//cell division;GO:0008306//associative learning;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0010669//epithelial structure maintenance;GO:0010469//regulation of receptor activity;GO:0001709//cell fate determination;GO:0007445;GO:0007431//salivary gland development;GO:0007476//imaginal disc-derived wing morphogenesis 41185 1417.31 20.18 21 0.0574631534471279 Up 0.142814687623828 Pnn pinin, isoform B K13114|1|7e-53|207|aag:AaeL_AAEL013522|pinin GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - GO:0000377;GO:0000377 2768896 607.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 Ste:CG33244 Ste:CG33244 K08282|1|2e-95|347|dme:Dmel_CG33236|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 14462583 288.00 0.315 0.215 -0.551015168797818 Down 0.0969819046361115 14462539 801.00 0.06 0.24 2 Up 0.157376832650905 35560 5316.00 4.37 4.41 0.0131453760569222 Up 0.0472856954167217 Bap170 brahma associated protein 170kD K11765|1|0.0|2557|dme:Dmel_CG3274|AT-rich interactive domain-containing protein 2 GO:0070603//SWI/SNF superfamily-type complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006909//phagocytosis;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0031647//regulation of protein stability 41940 811.00 12.295 13.275 0.110640126095434 Up 0.194062871483292 CG5516 CG5516, isoform B - - GO:0005488//binding - 43472 1916.00 4.8 4.515 -0.0883084181276601 Down 0.107680623431515 CG2006 CG2006, isoform B K12946|1|4e-29|92.8|dme:Dmel_CG11500|signal peptidase complex subunit 1 [EC:3.4.-.-];K01423|4|5e-23|84.0|dpo:Dpse_GA11036| [EC:3.4.-.-] - - - 3772363 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 318657 1454.00 0.19 0.115 -0.724365557386573 Down 0.0915334830273412 CG31279 CG31279, isoform G - - - - 37236 706.00 1.785 2.03 0.185555653156076 Up 0.121648395192181 CG7735 ADP ribosylation factor-like 6, isoform B K07951|1|2e-112|404|dme:Dmel_CG7735|ADP-ribosylation factor-like 6 - - - 14462596 351.00 3.725 4.205 0.17486537490562 Up 0.165830141328754 CG43788 CG43788 - - - - 43189 1970.87 1.11 1.655 0.576271540457112 Up 0.229626205256901 CG5432 CG5432, isoform B K01623|1|0.0|730|dme:Dmel_CG5432|fructose-bisphosphate aldolase, class I [EC:4.1.2.13] - GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559 GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process 33833 933.55 0.51 0.935 0.874469117916141 Up 0.218068947298904 Ucp4B uncoupling protein 4B, isoform C K08769|1|8e-26|117|cfa:403574|mitochondrial brown fat uncoupling protein 1 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity GO:0046907//intracellular transport;GO:0006818//hydrogen transport;GO:0046907//intracellular transport;GO:0006818//hydrogen transport 38406 967.17 6.17 5.17 -0.255106208834483 Down 0.261061946902655 CG14968 CG14968, isoform E K12474|1|5e-06|52.0|tca:662322|low density lipoprotein receptor adapter protein 1 - - - 19834830 1249.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 39745 863.00 31.97 29.76 -0.103344217672489 Down 0.22741381587637 Arf72A ADP ribosylation factor-like 1 K07942|1|3e-99|361|dgr:Dgri_GH14778|ADP-ribosylation factor-like 1 GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0050658//RNA transport;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0015031//protein transport;GO:0009790//embryo development;GO:0006464//cellular protein modification process 39280 1136.00 0.545 0.455 -0.26038968457823 Down 0.0834764231937657 CG7551 CG7551 K00846|1|0.0|656|dme:Dmel_CG7551|ketohexokinase [EC:2.7.1.3] - - - 37322 2030.00 5.75 6.24 0.117984073030511 Up 0.15222559767534 lms lateral muscles scarcer, isoform C K09360|1|3e-18|94.0|spu:580358|BarH-like;K09349|2|6e-18|92.8|dpe:Dper_GL13779|homeobox protein Nkx-5 - - - 35570 1280.58 15.04 14.13 -0.0900431013436981 Down 0.174250429269581 CG3271 Post-GPI attachment to proteins 3 ortholog, isoform B - - - - 34950 8785.14 24.165 35.525 0.555915654702418 Up 0.611081759344869 Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D, isoform J K05315|1|0.0|3709|dse:Dsec_GM18655|voltage-dependent calcium channel alpha 1, invertebrate GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part;GO:0034704//calcium channel complex;GO:0044459//plasma membrane part GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0005262//calcium channel activity;GO:0046872//metal ion binding GO:0070838//divalent metal ion transport;GO:0007275//multicellular organismal development;GO:0003012//muscle system process;GO:0042044//fluid transport;GO:0070838//divalent metal ion transport;GO:0007275//multicellular organismal development;GO:0003012//muscle system process;GO:0042044//fluid transport;GO:0070838//divalent metal ion transport;GO:0007275//multicellular organismal development;GO:0003012//muscle system process;GO:0042044//fluid transport;GO:0070838//divalent metal ion transport;GO:0007275//multicellular organismal development;GO:0003012//muscle system process;GO:0042044//fluid transport 19834948 915.55 4.615 6.055 0.391796312048554 Up 0.343580768722758 - sarcolamban B, isoform D - - - - 12798366 1786.03 24.165 15.195 -0.669322319905431 Down 0.614813102628451 37400 2498.25 4.715 5.57 0.240419556664935 Up 0.238673887201162 king-tubby king tubby, isoform C K09448|1|5e-89|329|cfa:481758|TEA domain family member 1/3/4 - - - 46234 2162.49 47.035 48.41 0.041570389862094 Up 0.127493065645225 fbl fumble, isoform G K09680|1|0.0|715|dme:Dmel_CG5725|type II pantothenate kinase [EC:2.7.1.33] GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559 GO:0007472//wing disc morphogenesis;GO:0009108//coenzyme biosynthetic process;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0051301//cell division;GO:0055088//lipid homeostasis;GO:0007472//wing disc morphogenesis;GO:0009108//coenzyme biosynthetic process;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0051301//cell division;GO:0055088//lipid homeostasis;GO:0007472//wing disc morphogenesis;GO:0009108//coenzyme biosynthetic process;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0051301//cell division;GO:0055088//lipid homeostasis;GO:0007472//wing disc morphogenesis;GO:0009108//coenzyme biosynthetic process;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0051301//cell division;GO:0055088//lipid homeostasis;GO:0007472//wing disc morphogenesis;GO:0009108//coenzyme biosynthetic process;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0051301//cell division;GO:0055088//lipid homeostasis 40053 595.69 72.865 113.545 0.639966276386822 Up 0.670552106723022 CG6852 CG6852, isoform C K03676|1|3e-60|229|dya:Dyak_GE23086|glutaredoxin 3 - GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis 3772080 1609.73 6.955 6.105 -0.188059219554836 Down 0.22381455554088 CG12788 CG12788, isoform E K10837|1|3e-165|582|dme:Dmel_CG12788|O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164];K10836|2|2e-45|183|dme:Dmel_CG17767|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 35811 1692.45 8.655 13.02 0.589123723798997 Up 0.534143442081627 CG2127 CG2127, isoform B - - - - 35569 3051.08 10.82 10.815 -0.000666833864836677 Down 0.0401862369568089 Hsepi heparan sulfate C5-epimerase, isoform B K01793|1|0.0|1157|dme:Dmel_CG3194|heparosan-N-sulfate-glucuronate 5-epimerase [EC:5.1.3.17] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0016854//racemase and epimerase activity;GO:0016854//racemase and epimerase activity GO:0006023;GO:0006023 38258 2263.00 1.61 1.31 -0.297493876577167 Down 0.15037643640206 Cnb centrobin, isoform B K10373|1|7e-08|59.7|ame:408583|tropomyosin 1;K10352|2|7e-08|59.7|cin:100176037|myosin heavy chain;K10362|3|1e-06|55.8|cfa:480630|myosin XVIII GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression 36547 1526.00 30.26 31.875 0.0750133544168456 Up 0.188746532822613 Aats-phe Phenylalanyl-tRNA synthetase K01889|1|0.0|900|dme:Dmel_CG13348|phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] GO:0044424//intracellular part GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0007033//vacuole organization;GO:0006418//tRNA aminoacylation for protein translation 37011 1382.00 14.725 17.36 0.237499313726656 Up 0.363789459780742 rdgBbeta rdgBbeta K01106|1|3e-41|169|gga:771549|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] - - - 34984 2328.67 106.59 94.005 -0.181262695542958 Down 0.386408664641395 Tpr2 tetratricopeptide repeat protein 2, isoform E K09527|1|0.0|845|dme:Dmel_CG4599|DnaJ homolog subfamily C member 7 - GO:0005515//protein binding;GO:0005515//protein binding - 8674005 789.82 2.555 2.925 0.195113333533145 Up 0.150310394928015 Sfp78E seminal fluid protein 78E, isoform B - - - - 33750 1818.21 1.79 1.72 -0.0575510225621583 Down 0.0598996169594505 CG7742 CG7742, isoform D - GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 35210 1115.00 16.335 9.965 -0.713024744599005 Down 0.593316602826575 CG17350 CG17350 - - - - 38230 909.00 21.795 24.53 0.170550030203605 Up 0.317461365737683 mRpL46 mitochondrial ribosomal protein L46 K08860|1|6e-23|107|nvi:100120665|eukaryotic translation initiation factor 2-alpha kinase [EC:2.7.11.1] - GO:0003824//catalytic activity;GO:0005198//structural molecule activity - 32611 1829.00 4.22 3.83 -0.139898606782228 Down 0.143640206049399 Traf-like TNF-receptor-associated factor-like, isoform G K03174|1|7e-20|99.0|dre:445119|TNF receptor-associated factor 3 - - GO:0006950//response to stress;GO:0006950//response to stress;GO:0006950//response to stress 40497 809.00 1.545 1.155 -0.419713986488317 Down 0.183892484480254 CG14448 CG14448 - - - - 326115 2291.06 10.565 9.075 -0.219323219051828 Down 0.294445912032757 CG31033 Autophagy-specific gene 16, isoform F K12857|1|2e-30|133|ecb:100070474|Prp8 binding protein - - - 35134 450.00 0.56 0.625 0.158429362604483 Up 0.0673292827895919 CG15167 CG15167 - - - - 33247 3133.24 120.92 177.24 0.551651347858238 Up 0.655890899484877 Eaat2 excitatory amino acid transporter 2, isoform D K05613|1|4e-95|350|mdo:100009860|solute carrier family 1 (glial high affinity glutamate transporter), member 2 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity GO:0015718//monocarboxylic acid transport;GO:0015718//monocarboxylic acid transport;GO:0015718//monocarboxylic acid transport 41990 1054.00 7.415 9.4 0.342214064110369 Up 0.377096816800951 CG14881 CG14881, isoform B - - - - 33453 1140.00 0.105 0.08 -0.39231742277876 Down 0.0612534671773874 Gr23a gustatory receptor 23a, isoform C K08471|1|4e-46|185|dme:Dmel_CG15396|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 33727 6000.92 70.16 69.78 -0.00783515025035835 Down 0.0656122044644036 Cg25C collagen type IV, isoform C K06237|1|0.0|2882|dme:Dmel_CG4145|collagen, type IV, alpha GO:0005604//basement membrane;GO:0005604//basement membrane;GO:0005604//basement membrane GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0001700//embryonic development via the syncytial blastoderm;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001700//embryonic development via the syncytial blastoderm 36433 553.92 4.84 2.765 -0.807727567039887 Down 0.452714304583278 CG13323 CG13323, isoform B - - - - 38181 2935.00 78.99 73.085 -0.112094684958979 Down 0.268194426099591 CG12099 CG12099, isoform B K00764|1|4e-06|53.9|dwi:Dwil_GK12572|amidophosphoribosyltransferase [EC:2.4.2.14] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 41538 2004.00 75.06 63.765 -0.235279530526645 Down 0.449214106458856 CG18549 CG18549 - - - - 19834795 267.00 0.175 0.585 1.74108170263844 Up 0.242966583014133 - CG45012 - - - - 19836134 5792.00 1.72 2.78 0.69267631802141 Up 0.329679038436138 37841 735.00 202.145 173.38 -0.221453031242305 Down 0.447034737815348 tsr twinstar K05765|1|2e-81|301|dya:Dyak_GE11491|cofilin GO:0015630//microtubule cytoskeleton GO:0008092//cytoskeletal protein binding GO:0030032//lamellipodium assembly;GO:0008154//actin polymerization or depolymerization;GO:0008406//gonad development;GO:0007297//ovarian follicle cell migration;GO:0001736//establishment of planar polarity;GO:0035110;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0001654//eye development 39733 2740.11 42 44.555 0.085198013405477 Up 0.217705719191652 Pka-C3 cAMP-dependent protein kinase 3, isoform B K04345|1|0.0|868|dsi:Dsim_GD12529|protein kinase A [EC:2.7.11.11] GO:0043234//protein complex;GO:0043234//protein complex GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0007472//wing disc morphogenesis;GO:0006464//cellular protein modification process;GO:0007472//wing disc morphogenesis 35751 627.00 0.64 0.645 0.0112272554232541 Up 0.041044776119403 CG11165 CG11165 K02183|1|4e-43|174|bta:514457|calmodulin - GO:0046872//metal ion binding - 32434 618.42 143.525 143.945 0.00421562144440592 Up 0.0469224673094703 CG5548 CG5548, isoform C K03963|1|7e-52|202|dme:Dmel_CG5548|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 7 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0046872//metal ion binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0022904//respiratory electron transport chain 39330 3007.00 0.19 0.185 -0.0384741478146357 Down 0.0418702945449742 CG5964 CG5964 K10392|1|4e-11|70.9|bfo:BRAFLDRAFT_227179|kinesin family member 1/13/14;K05702|2|1e-10|68.9|hmg:100201659|afadin;K06267|3|3e-10|67.8|oaa:100079090|hyaluronan-mediated motility receptor;K04514|5|1e-09|65.9|mmu:19878|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - - - 41773 564.74 625.955 627.6 0.00378640698579157 Up 0.0476489235239731 His4r histone H4 replacement, isoform D K11254|1|2e-40|164|cqu:CpipJ_CPIJ014768|histone H4 - - - 33235 4182.19 10.4 12.27 0.238551720634451 Up 0.327664773477744 CG2807 CG2807, isoform B K12828|1|0.0|2532|dme:Dmel_CG2807|splicing factor 3B subunit 1 GO:0032991//macromolecular complex GO:0005488//binding - 37482 2701.00 2.6 1.685 -0.625763031846596 Down 0.303724739136178 LBR lamin B receptor, isoform C K00222|1|2e-18|95.1|xtr:100127815|delta14-sterol reductase [EC:1.3.1.70] GO:0012505//endomembrane system;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system;GO:0019866//organelle inner membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding - 246584 2302.00 0.265 0.545 1.04026387021373 Up 0.18234050984018 CG30384 CG30384 - - - - 43115 854.84 0.515 0.51 -0.0140751852117228 Down 0.041044776119403 CG4960 CG4960, isoform B K11449|1|1e-13|76.3|cfa:474695|jumonji domain-containing protein 1 [EC:1.14.11.-] - - - 33641 811.00 5.56 5.705 0.0371420035651742 Up 0.0709285431250826 Psf2 Psf2, isoform C K10733|1|3e-110|397|dme:Dmel_CG18013|GINS complex subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003678//DNA helicase activity;GO:0030528//transcription regulator activity GO:0006259//DNA metabolic process;GO:0007090//regulation of S phase of mitotic cell cycle 37854 1963.00 4.395 4.43 0.0114435334116143 Up 0.0472856954167217 CG10339 CG10339 K07378|1|1e-55|218|dre:562702|neuroligin - - - 42463 1356.13 33.07 31.6 -0.0655984871266495 Down 0.172896579051644 CG17271 CG17271, isoform B - - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 33964 3341.00 7.59 7.505 -0.0162478137947779 Down 0.0559701492537313 Rat1 Rat1, isoform B K12619|1|0.0|1615|dme:Dmel_CG10354|5'-3' exoribonuclease 2 [EC:3.1.13.-] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0008409//5'-3' exonuclease activity GO:0006308//DNA catabolic process 39573 687.70 3.095 6.49 1.06827906878487 Up 0.552502971866332 CG7768 CG7768, isoform B K01802|1|2e-93|341|dme:Dmel_CG7768|peptidylprolyl isomerase [EC:5.2.1.8];K09565|2|1e-81|302|dmo:Dmoj_GI21755|peptidyl-prolyl isomerase F (cyclophilin F) [EC:5.2.1.8] GO:0015630//microtubule cytoskeleton;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0008023//transcription elongation factor complex GO:0016859//cis-trans isomerase activity;GO:0019887//protein kinase regulator activity GO:0044267//cellular protein metabolic process;GO:0048102//autophagic cell death 12798165 153.00 0.395 0.825 1.06254146606871 Up 0.229527143045833 19834974 561.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 14462748 363.00 0.475 0.295 -0.687212558969106 Down 0.130828160084533 44160 2868.23 47.64 60.775 0.351304575051977 Up 0.541507066437723 sw short wing, isoform O K10415|1|0.0|1107|dme:Dmel_CG18000|dynein intermediate chain, cytosolic GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0003774//motor activity;GO:0045502//dynein binding GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport;GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport 38065 4498.14 5.99 5.445 -0.137623954071879 Down 0.166919825650509 trh trachealess, isoform G K09098|1|4e-109|397|xtr:780104|neuronal PAS domain-containing protein 1/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0030528//transcription regulator activity;GO:0060089;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0048812//neuron projection morphogenesis;GO:0042428//serotonin metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0042749//regulation of circadian sleep/wake cycle;GO:0023060;GO:0001709//cell fate determination;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0048598//embryonic morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0042428//serotonin metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0042749//regulation of circadian sleep/wake cycle;GO:0023060;GO:0001709//cell fate determination;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0048598//embryonic morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0042428//serotonin metabolic process;GO:0006355//regulation of transcription, DNA-dependent;GO:0042749//regulation of circadian sleep/wake cycle;GO:0023060;GO:0001709//cell fate determination;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0048598//embryonic morphogenesis 40919 838.00 0.34 0.585 0.782901878333065 Up 0.156584334962356 CG11286 CG11286, isoform B - - - - 42176 652.00 0.45 0.755 0.746551642995404 Up 0.176958129705455 CG14313 CG14313 - - - - 39141 3227.00 2.765 2.475 -0.159850955267735 Down 0.126799630167745 defl deflated K13144|1|0.0|1950|dme:Dmel_CG18176|integrator complex subunit 7 GO:0043231//intracellular membrane-bounded organelle - - 19835165 601.00 0.075 0.405 2.43295940727611 Up 0.226984546295073 34985 4188.40 11.785 7.07 -0.737169638440769 Down 0.566074494782724 CG5953 CG5953, isoform D - - - - 31668 2047.00 0.58 0.82 0.499571009490512 Up 0.14515915995245 CG18155 CG18155 K01896|1|2e-09|64.7|mdo:100026277|medium-chain acyl-CoA synthetase [EC:6.2.1.2];K01904|4|3e-07|57.4|spu:581911|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 50365 987.00 26.315 23.81 -0.144317774222439 Down 0.283218861444987 CG3713 CG3713, isoform B - - - - 5740378 497.00 0.435 0.295 -0.560300446486887 Down 0.112897899881125 CG34328 CG34328 - - - - 44855 3956.00 0.175 0.195 0.156119201917282 Up 0.0504556861709153 rib ribbon, isoform C K09237|1|2e-19|99.0|phu:Phum_PHUM489940|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0035296//regulation of tube diameter;GO:0006996//organelle organization;GO:0048870//cell motility;GO:0035148//tube formation;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0010468//regulation of gene expression;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development;GO:0033036;GO:0007431//salivary gland development;GO:0060446//branching involved in open tracheal system development 31207 1267.00 0.19 0.255 0.42449782852791 Up 0.0781931052701096 Or2a odorant receptor 2a K08471|1|0.0|772|dme:Dmel_CG3206|gustatory receptor - - - 35003 521.87 14.38 14.52 0.0139777775564528 Up 0.0576542068418967 LSm7 LSm7, isoform C K12626|1|1e-56|219|dya:Dyak_GE13166|U6 snRNA-associated Sm-like protein LSm7 GO:0005681//spliceosomal complex - GO:0000377 40178 1242.00 26.4 29.68 0.168953162374988 Up 0.328127063796064 CG8004 CG8004 - GO:0031966//mitochondrial membrane - - 36602 1514.00 0.055 0.12 1.12553088208386 Up 0.0856557918372738 CG10104 CG10104 K01379|1|0.0|798|dme:Dmel_CG10104|cathepsin D [EC:3.4.23.5];K06002|1|0.0|798|dme:Dmel_CG10104|pepsin A [EC:3.4.23.1] GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0048102//autophagic cell death 31785 1615.40 0.18 0.22 0.289506617194985 Up 0.0645885616166953 Cp7Fb chorion protein b at 7F, isoform B - - - - 19835201 590.00 0.215 0.49 1.18844508941311 Up 0.184949148064985 39387 4940.00 27.58 26.06 -0.0817853729458457 Down 0.186567164179104 Nrx-IV neurexin IV, isoform B K07380|1|0.0|642|tgu:100223892|contactin associated protein-like 2 GO:0016021//integral to membrane;GO:0005918//septate junction;GO:0016021//integral to membrane;GO:0005918//septate junction GO:0046872//metal ion binding;GO:0004872//receptor activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0046872//metal ion binding;GO:0004872//receptor activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups GO:0033036;GO:0007043//cell-cell junction assembly;GO:0006904//vesicle docking involved in exocytosis;GO:0001885//endothelial cell development;GO:0035150//regulation of tube size;GO:0009058//biosynthetic process;GO:0007272;GO:0001700//embryonic development via the syncytial blastoderm;GO:0021675//nerve development;GO:0006903//vesicle targeting;GO:0021782//glial cell development;GO:0033036;GO:0007043//cell-cell junction assembly;GO:0006904//vesicle docking involved in exocytosis;GO:0001885//endothelial cell development;GO:0035150//regulation of tube size;GO:0009058//biosynthetic process;GO:0007272;GO:0001700//embryonic development via the syncytial blastoderm;GO:0021675//nerve development;GO:0006903//vesicle targeting;GO:0021782//glial cell development 38344 6262.09 18.755 15.73 -0.253756592245783 Down 0.382115968828424 Atg2 Autophagy-specific gene 2, isoform B - - - GO:0007552//metamorphosis 40420 725.00 18.685 5.365 -1.80023048762422 Down 0.721569145423326 CG14567 CG14567 - - - - 33166 1576.02 15.99 16.225 0.0210485394061692 Up 0.0722823933430194 CG11377 CG11377, isoform B K04591|1|4e-07|56.6|ecb:100066036|egf-like module containing, mucin-like, hormone receptor-like 1;K08023|2|5e-07|56.2|gga:428888|latent transforming growth factor beta binding protein;K06242|3|8e-07|55.5|xtr:100145762|laminin, alpha 5;K02599|4|4e-06|53.1|dre:58065|Notch - GO:0046872//metal ion binding - 41912 1270.00 2.865 3.62 0.3374545583263 Up 0.247952714304583 CG9593 CG9593 K10104|1|8e-31|134|bfo:BRAFLDRAFT_252169|ficolin;K06252|4|7e-28|124|mdo:100021328|tenascin - - - 252671 4915.41 23.36 27.145 0.216646209649267 Up 0.37987055871087 X11L X11L, isoform F K04531|1|1e-131|471|gga:427246|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) GO:0016020//membrane;GO:0044424//intracellular part;GO:0016020//membrane;GO:0044424//intracellular part GO:0005488//binding;GO:0005488//binding GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis 35567 537.00 16.365 19.82 0.276343360141725 Up 0.413881917844406 CG15908 CG15908 - - - - 318554 529.00 0.925 1.21 0.387481776758282 Up 0.152489763571523 CG31008 CG31008 - - - - 19835932 238.00 0.825 1.075 0.381870635343644 Up 0.142616563201691 14462876 604.00 19.69 14.285 -0.462962074965182 Down 0.531237617223616 5740853 3444.54 6.24 6.355 0.0263460961427106 Up 0.0651829348831066 lmgA lemming A, isoform D K03358|1|3e-132|303|dan:Dana_GF14365|anaphase-promoting complex subunit 11 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007067//mitosis;GO:0007067//mitosis 19836256 309.00 0.29 0.355 0.29176612437711 Up 0.0739334301941619 36540 1245.05 50.835 76.305 0.585955457378635 Up 0.650112270505878 CG16935 CG16935, isoform B K07512|1|0.0|705|dme:Dmel_CG16935|mitochondrial trans-2-enoyl-CoA reductase [EC:1.3.1.38] - GO:0003824//catalytic activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process 40938 2982.01 0.24 0.31 0.369233809665719 Up 0.0818914278166689 CG10445 CG10445, isoform E K10875|1|2e-20|102|ame:409447|DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.1.-];K10877|3|2e-19|98.2|phu:Phum_PHUM565420|DNA repair and recombination protein RAD54B [EC:3.6.1.-];K11727|4|7e-19|96.7|gga:422358|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:3.6.1.-] - GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0032559 - 41599 8118.37 14.035 16.225 0.209189414373977 Up 0.328556333377361 CG7518 CG7518, isoform J - - - - 36940 646.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 CG30457 CG30457 - - - - 14462521 1283.00 0.18 0.34 0.917537839808027 Up 0.131587637036059 37419 2358.90 78.375 72.145 -0.119494125528947 Down 0.284902919033153 Glycogenin glycogenin, isoform I K00750|1|6e-143|507|dpo:Dpse_GA21819|glycogenin glucosyltransferase [EC:2.4.1.186] - GO:0016740//transferase activity GO:0009888//tissue development 31111 5602.76 4.98 5.71 0.197345003294762 Up 0.211563862105402 Mur2B mucin related 2B, isoform C - GO:0030312//external encapsulating structure GO:0030247//polysaccharide binding GO:0006022 36092 816.19 3.87 6.315 0.706449167643142 Up 0.469521859727909 CG12902 CG12902, isoform C - - - - 37923 3139.00 21.865 18.305 -0.256385574776662 Down 0.40315017831198 CG11414 CG11414 - GO:0044464//cell part GO:0046914//transition metal ion binding - 31851 1853.00 8.975 8.585 -0.06409380470828 Down 0.113162065777308 Zpr1 Zpr1 K06874|1|0.0|887|dme:Dmel_CG9060| - GO:0046914//transition metal ion binding GO:0006351//transcription, DNA-dependent 3772597 1357.00 55.63 9.66 -2.52576801141784 Down 0.790681548012152 39914 1551.00 12.23 12.99 0.0869770269204943 Up 0.165037643640206 Papst2 PAPS transporter 2 - GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0015211//purine nucleoside transmembrane transporter activity GO:0032501//multicellular organismal process;GO:0015860//purine nucleoside transmembrane transport 32022 1398.00 0.955 1.995 1.0628161081866 Up 0.355105005943733 CG15208 CG15208, isoform C K10411|1|4e-07|56.2|tad:TRIADDRAFT_56121|dynein light chain 1, axonemal - - GO:0048102//autophagic cell death 35368 3340.00 0.915 0.92 0.0078621177729701 Up 0.0382380134724607 betaInt-nu integrin betanu subunit K05719|1|0.0|1279|dpo:Dpse_GA14581|integrin beta 1 GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0016337//cell-cell adhesion;GO:0032501//multicellular organismal process;GO:0031589//cell-substrate adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007635//chemosensory behavior 31899 3378.00 24.23 30.595 0.336501494383411 Up 0.499240523048474 CG32699 CG32699 K13510|1|0.0|996|dme:Dmel_CG32699|lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] - GO:0046872//metal ion binding;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 38174 2801.00 30.135 29.535 -0.0290144528317381 Down 0.099524501386871 cue cueball K04550|1|5e-36|153|dre:565797|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) GO:0031224//intrinsic to membrane GO:0030169//low-density lipoprotein particle binding GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0048869//cellular developmental process 35434 1151.00 0.47 0.745 0.664579668784524 Up 0.16044776119403 CG11634 CG11634, isoform B - - GO:0003824//catalytic activity - 34957 2439.00 25.62 24.75 -0.0498419504873121 Down 0.132776383568881 pkaap pkaap - - GO:0060089 GO:0033036 40226 1947.00 0.84 1.17 0.478047296804644 Up 0.171905956940959 CG17122 CG17122 K04514|1|3e-11|70.5|dmo:Dmoj_GI11100|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1];K06267|2|5e-11|69.7|ecb:100070798|hyaluronan-mediated motility receptor;K10352|3|3e-10|67.4|cqu:CpipJ_CPIJ015899|myosin heavy chain - - - 42957 2043.00 3.7 3.075 -0.26693886028971 Down 0.20991282525426 CG5808 CG5808 K12735|1|0.0|880|dme:Dmel_CG5808|peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity;GO:0005488//binding GO:0000377;GO:0044267//cellular protein metabolic process 38299 2130.00 0.025 0.085 1.76553474636298 Up 0.0883304715361247 CG13801 CG13801 - GO:0031224//intrinsic to membrane GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006842//tricarboxylic acid transport 14462716 426.00 0.205 0.27 0.397335497545385 Up 0.0775326905296526 3355125 2491.49 9.16 7.44 -0.300044976988913 Down 0.34500066041474 CG17490 CG17490, isoform G - - - - 326251 3013.77 11.77 11.03 -0.0936815294470615 Down 0.163320565315018 CG33096 CG33096, isoform G K06889|1|8e-13|75.5|ame:412636| GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity - 19835208 368.00 0.235 0.135 -0.799701349514169 Down 0.101637828556333 37583 5048.45 8.285 11.525 0.476193148095249 Up 0.476621318187822 CG33143 CG33143, isoform F - - - - 38363 1136.00 49.86 65.35 0.390304353191295 Up 0.568220842689209 CG32485 CG32485 K01104|1|4e-07|55.8|ssc:100157097|protein-tyrosine phosphatase [EC:3.1.3.48] - - - 10178963 812.40 1.195 1.435 0.264040118694939 Up 0.125709945845991 CG42764 CG42764, isoform C - - - - 64877 3761.71 941.6 1122.3 0.253272146233538 Up 0.488145555408797 cpx complexin, isoform Z - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity;GO:0000149//SNARE binding;GO:0022857//transmembrane transporter activity GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis;GO:0007416//synapse assembly;GO:0050804//regulation of synaptic transmission;GO:0006887//exocytosis 8674029 566.00 4.23 4.735 0.162706762348435 Up 0.166688680491349 CG42561 CG42561 - - - - 35227 3492.00 3.4 3.045 -0.159092518231369 Down 0.142253335094439 tj traffic jam, isoform C K09036|1|4e-101|369|dpo:Dpse_GA10021|transcription factor MAFB GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 261628 613.00 9.69 7.375 -0.393853616278515 Down 0.411306300356624 CG31469 CG31469 K01104|1|2e-92|337|dme:Dmel_CG31469|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 7354443 1484.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 14462501 532.00 0.01 0.555 5.79441586635011 Up 0.379012019548276 43122 195.00 168.805 187.5 0.151532958338468 Up 0.349689605071985 Mst57Db Male-specific RNA 57Db - - - GO:0019098//reproductive behavior 326175 1351.00 0.035 0.035 0 - 0.0382380134724607 CG31928 CG31928, isoform B K01379|1|8e-64|244|dme:Dmel_CG6508|cathepsin D [EC:3.4.23.5];K06002|1|8e-64|244|dme:Dmel_CG6508|pepsin A [EC:3.4.23.1] GO:0030312//external encapsulating structure GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41107 2741.00 15.78 15.78 -1.60171325190746e-16 Down 0.0382380134724607 Vps16A vacuolar protein sorting 16A - GO:0044444//cytoplasmic part - GO:0016192//vesicle-mediated transport;GO:0016236//macroautophagy;GO:0048753//pigment granule organization;GO:0015031//protein transport 8674028 384.00 0.665 0.77 0.211504105193712 Up 0.0824858010830802 CG42463 CG42463 - - GO:0004866//endopeptidase inhibitor activity - 32932 993.00 0.205 0.185 -0.148098638989134 Down 0.0503566239598468 CG12200 CG12200 - - GO:0046914//transition metal ion binding - 39831 3496.00 0.08 0.04 -1 Down 0.0725795799762251 dsx-c73A doublesex cognate 73A - - - - 19835766 795.00 0.105 0.06 -0.807354922057604 Down 0.07657508915599 4379861 1032.00 2.705 2.18 -0.311300459049889 Down 0.203110553427552 CG34149 CG34149, isoform B - - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - 41011 1239.00 0.04 0.01 -2 Down 0.0694426099590543 Or85d odorant receptor 85d K08471|1|0.0|807|dme:Dmel_CG11742|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38943 2029.00 31.36 28.59 -0.13341493948411 Down 0.277968564258354 CG7083 CG7083 - - - - 41665 2406.00 1.365 2.43 0.832055362685929 Up 0.344010038304055 CG10841 CG10841, isoform B - - - - 19835832 403.00 1.985 1.415 -0.488336954311076 Down 0.230088495575221 38057 2624.63 12.53 11.87 -0.0780664796799537 Down 0.149947166820763 mthl10 methuselah-like 10, isoform G K04599|1|1e-84|313|dme:Dmel_CG6530|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0023060 41427 6722.00 9.31 11.22 0.269219603049999 Up 0.344538370096421 Sbf SET domain binding factor, isoform B K01112|1|4e-35|151|mmu:53332| [EC:3.1.3.-];K01104|2|4e-33|145|dre:393838|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0023033;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0023033 44269 1608.00 1.39 1.19 -0.224123309415564 Down 0.111841236296394 sut2 sugar transporter 2 K07299|1|2e-59|229|dre:555778|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1;K08142|2|2e-59|229|mmu:20527|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3 GO:0031224//intrinsic to membrane GO:0005402//cation:sugar symporter activity GO:0006810//transport 34840 1251.60 104.745 123.865 0.241887210377438 Up 0.461431779157311 Rab14 Rab14, isoform D K07881|1|1e-113|409|dya:Dyak_GE19031|Ras-related protein Rab-14 - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0006810//transport 14462496 351.00 1.69 2.495 0.562016569055076 Up 0.280643243957205 37351 1604.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG13443 CG13443 - - - - 19834925 1137.00 0.04 0.345 3.10852445677817 Up 0.227017567032096 38278 1552.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 CG13810 CG13810 - - - - 36332 2967.90 4.165 7.715 0.889349661205187 Up 0.544247787610619 SIP2 syntaxin interacting protein 2, isoform G K10352|1|1e-15|85.9|rno:24583|myosin heavy chain - - - 3772203 595.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 His2B:CG33904 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 31409 1411.00 0.275 0.245 -0.166649869409451 Down 0.0560692114647999 CG15472 CG15472 - - - - 8674056 1718.00 2.005 1.89 -0.0852160022338475 Down 0.072810725135385 CG42487 CG42487 - - - - 2768982 388.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG33270 CG33270 - - - - 34644 626.00 0.775 1.005 0.374927285904691 Up 0.135517104741778 CG17217 CG17217 - - - - 12798003 597.00 0.07 0.28 2 Up 0.171377625148593 38798 3594.23 13.3 14.35 0.109624491174498 Up 0.198916919825651 Cdc27 cell division cycle 27 ortholog, isoform B K03350|1|0.0|1604|dme:Dmel_CG8610|anaphase-promoting complex subunit 3 GO:0005681//spliceosomal complex - GO:0000377 14462692 789.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 CG43797 CG43797 - - - - 35076 1623.13 0.355 0.565 0.670431842910506 Up 0.140668339717342 elfless elfless, isoform C K12170|1|6e-07|55.8|mcc:706726|E3 ubiquitin-protein ligase RNF125 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 34353 936.00 52.945 47.51 -0.156263239210017 Down 0.338561616695285 CG34159 CG34159 - - - - 32426 2627.87 77.89 79.95 0.0376599156430509 Up 0.131851802932241 pdgy pudgy, isoform D K01904|1|1e-102|374|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 3772374 529.00 0.01 0.01 0 - 0.0382380134724607 His3:CG33824 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 36725 2280.00 20.015 20.69 0.0478520294724707 Up 0.125280676264694 CG8195 CG8195 - GO:0044464//cell part - - 34313 1391.00 186.555 179.595 -0.0548538420169037 Down 0.15813630960243 yip2 yippee interacting protein 2 K07508|1|0.0|701|dme:Dmel_CG4600|acetyl-CoA acyltransferase 2 [EC:2.3.1.16] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups GO:0009062//fatty acid catabolic process 41785 1653.40 248.105 224.025 -0.147291071437341 Down 0.35206709813763 eff effete, isoform C K06689|1|1e-84|314|api:100145836|ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] - - - 41836 1828.00 15.78 12.48 -0.33847927115121 Down 0.439968300092458 Caf1 chromatin assembly factor 1 subunit, isoform B K10752|1|0.0|899|dme:Dmel_CG4236|histone-binding protein RBBP4 GO:0005678//chromatin assembly complex;GO:0005694//chromosome;GO:0031519//PcG protein complex;GO:0031010 GO:0018024//histone-lysine N-methyltransferase activity;GO:0004468//lysine N-acetyltransferase activity;GO:0019899//enzyme binding GO:0000278//mitotic cell cycle;GO:0006277//DNA amplification;GO:0016458//gene silencing;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0051301//cell division;GO:0048513//organ development;GO:0006334//nucleosome assembly;GO:0006479//protein methylation 3772221 1343.00 104.485 110.41 0.0795750030670637 Up 0.214502707700436 sea scheggia, isoform E K03454|1|5e-95|348|rno:29743|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 34910 2680.51 19.21 18.655 -0.0422951588487471 Down 0.11028926165632 lace lace, isoform B K00654|1|0.0|1152|dme:Dmel_CG4162|serine palmitoyltransferase [EC:2.3.1.50] - GO:0016454;GO:0048037//cofactor binding GO:0008152//metabolic process 44098 1673.00 2.12 2.58 0.283306800860055 Up 0.1828028001585 rasp rasp - GO:0031224//intrinsic to membrane GO:0008415 GO:0007224//smoothened signaling pathway;GO:0006500 36576 561.41 1018.005 1040.905 0.032093757255934 Up 0.117487782327302 RpS23 ribosomal protein S23, isoform B K02973|1|1e-78|292|dvi:Dvir_GJ22302|small subunit ribosomal protein S23e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 34531 886.00 5.18 3.23 -0.681417932992629 Down 0.429203539823009 Acp32CD accessory gland protein 32CD, isoform B - - - - 317841 937.00 0.745 2.035 1.44971646380409 Up 0.410612864879144 Elo68alpha elongase 68alpha K10249|1|2e-159|561|dme:Dmel_CG32072|elongation of very long chain fatty acids protein 4 GO:0031224//intrinsic to membrane GO:0004312//fatty acid synthase activity GO:0042446//hormone biosynthetic process;GO:0030497//fatty acid elongation 42158 1747.00 11.695 11.785 0.01105989689774 Up 0.053625676925109 CG7785 CG7785 - - - - 33394 1483.93 24.32 22.765 -0.0953257694243864 Down 0.211960110949676 CG10874 CG10874, isoform D - - - - 32224 2853.00 1.98 2.1 0.0848888975865126 Up 0.0739664509311848 CG15725 CG15725 - GO:0044464//cell part GO:0046914//transition metal ion binding - 33027 1649.40 0.995 0.82 -0.279072615925565 Down 0.110091137234183 Inx7 innexin 7, isoform B K12398|1|3e-45|183|dya:Dyak_GE17549|AP-3 complex subunit mu GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic to membrane GO:0022829//wide pore channel activity;GO:0022829//wide pore channel activity - 19834918 2210.00 0.635 1.185 0.900058562126093 Up 0.253136970017171 42473 3607.00 17.93 18.535 0.047876626950781 Up 0.122539955091798 CG3822 CG3822 K05202|1|0.0|762|mdo:100020889|glutamate receptor, ionotropic, kainate 2 GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 14462448 6412.00 0.475 0.88 0.889576010306349 Up 0.214337604015322 34063 2348.62 40.07 50.355 0.329612527987908 Up 0.52096816800951 CG7149 CG7149, isoform C K00993|1|0.0|869|der:Dere_GG23508|ethanolaminephosphotransferase [EC:2.7.8.1] GO:0044464//cell part GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006909//phagocytosis;GO:0006644//phospholipid metabolic process 34804 4564.62 43.905 45.365 0.047194412279376 Up 0.144168537841765 Smg5 Smg5, isoform C K11125|1|0.0|2146|dme:Dmel_CG8954|EST1-like protein B - - GO:0035194//posttranscriptional gene silencing by RNA;GO:0035194//posttranscriptional gene silencing by RNA 19835657 789.25 5.51 8.36 0.601450623509725 Up 0.479329018623696 - sarcolamban A, isoform C - - - - 32472 1720.00 20.745 13.925 -0.575086329644256 Down 0.580405494650641 CG11655 CG11655 K03453|1|2e-41|170|isc:IscW_ISCW015359|bile acid:Na+ symporter, BASS family GO:0044464//cell part GO:0005343//organic acid:sodium symporter activity GO:0030001//metal ion transport 19835062 1242.33 2.47 0.295 -3.06572418222284 Down 0.554418174613657 43826 3671.00 24.185 31.405 0.376881731554277 Up 0.526746796988509 Actbeta Activin-beta K04667|1|0.0|1784|dme:Dmel_CG11062|inhibin, beta - - - 40158 1061.70 20.9 21.63 0.0495307229937335 Up 0.128087438911637 CG14103 CG14103, isoform B - - - - 38414 3063.00 3.46 1.025 -1.75514812813128 Down 0.534605732399947 CG14961 CG14961 K06115|1|2e-21|105|dsi:Dsim_GD13758|spectrin beta - GO:0008092//cytoskeletal protein binding - 19835546 1673.00 22.29 23.23 0.0595925375490553 Up 0.147602694492141 41688 4019.86 243.87 160.445 -0.604033462812226 Down 0.672236164311187 CG9297 CG9297, isoform E K12483|1|4e-45|184|dwi:Dwil_GK13731|EH domain-containing protein 1 - - - 326173 2421.85 41.895 43.49 0.0539056344629623 Up 0.145720512481839 CG44001 CG44001, isoform E K10380|1|1e-13|78.6|dya:Dyak_GE14529|ankyrin - - - 43353 3037.00 30.265 36.95 0.287924013323316 Up 0.470017170783252 mfrn mitoferrin K03454|1|5e-80|299|dre:387000|mitochondrial carrier protein, MC family GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0015082 GO:0006826//iron ion transport;GO:0003006//developmental process involved in reproduction 19835940 378.00 0.455 0.16 -1.5077946401987 Down 0.200204728569542 19835288 584.00 9.56 9.87 0.0460394664756496 Up 0.098864086646414 32173 1298.00 0.385 0.46 0.256775415362111 Up 0.0762448817857615 CG1950 Uch-L5-related K05610|1|5e-172|603|dme:Dmel_CG1950|ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12] GO:0044464//cell part GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process 41177 946.00 59.475 49.85 -0.254689862026939 Down 0.45307753269053 eca eclair K01529|1|8e-14|77.8|mcc:709884| [EC:3.6.1.-];K05409|2|2e-06|53.5|ptr:471605|TRIF-related adaptor molecule GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane - GO:0003002//regionalization;GO:0051234//establishment of localization;GO:0002118//aggressive behavior 43388 2274.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 CG9988 CG9988 - - - - 3771920 3565.28 9.24 9.525 0.0438262409646266 Up 0.0909391097609299 PGRP-LD peptidoglycan recognition protein LD, isoform D K01446|1|7e-11|69.7|tca:658396|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding GO:0000270//peptidoglycan metabolic process;GO:0051234//establishment of localization;GO:0002376//immune system process;GO:0000270//peptidoglycan metabolic process;GO:0051234//establishment of localization;GO:0002376//immune system process;GO:0000270//peptidoglycan metabolic process;GO:0051234//establishment of localization;GO:0002376//immune system process;GO:0000270//peptidoglycan metabolic process;GO:0051234//establishment of localization;GO:0002376//immune system process 35918 1770.15 20.575 20.595 0.00140169555926883 Up 0.0416061286487914 CG8080 CG8080, isoform E - - GO:0016301//kinase activity - 317878 7465.33 0.43 0.72 0.743660246740214 Up 0.172797516840576 Nxf3 nuclear export factor 3, isoform C - - - - 40718 1505.00 7.75 7.745 -0.000931071372031396 Down 0.0382380134724607 CG1218 CG1218 - - - - 40846 914.00 30.61 28.165 -0.120099573287443 Down 0.258354246466781 Dpck Dephospho-CoA kinase K00859|1|1e-106|385|dwi:Dwil_GK14519|dephospho-CoA kinase [EC:2.7.1.24];K02318|5|1e-24|113|nvi:100116195|phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24] GO:0044424//intracellular part GO:0016301//kinase activity;GO:0032559 GO:0009108//coenzyme biosynthetic process 36458 2114.61 11.215 12.445 0.150136609894764 Up 0.240886276581693 CG4630 CG4630, isoform B K08202|1|4e-88|325|dgr:Dgri_GH14185|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 35241 3227.00 17.315 21.55 0.315665481779232 Up 0.456346585655792 CG10137 CG10137 - - GO:0008144//drug binding;GO:0016597//amino acid binding - 39507 666.00 30.295 13.6 -1.15547305408924 Down 0.701624620261524 CG14105 CG14105 - - - - 41170 2326.44 40.09 48.065 0.261744316289076 Up 0.453638885219918 Dh44 diuretic hormone 44, isoform C - - GO:0005179//hormone activity;GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0046903//secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0046903//secretion 7354431 1949.00 0.73 0.97 0.410088283307111 Up 0.140272090873068 CG42266 CG42266 - - - - 30971 6882.95 10.335 10.955 0.0840510955647747 Up 0.146645093118478 G9a G9a, isoform B K11420|1|0.0|2884|dme:Dmel_CG2995|euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] - - - 246487 507.00 20 10.08 -0.988504361162171 Down 0.658532558446705 CG30154 CG30154 - - - - 31810 1885.00 10.76 9.41 -0.193411449828088 Down 0.271034209483556 CG1785 CG1785 - - - - 43245 1396.00 0.195 0.04 -2.28540221886225 Down 0.147833839651301 TwdlC TweedleC - - GO:0030247//polysaccharide binding GO:0006022 5740377 415.00 36.495 31.34 -0.219693641187005 Down 0.398890503236032 CG34228 CG34228 - - - - 7354475 567.66 11.865 18.43 0.635343970436765 Up 0.585688812574297 CG42259 CG42259, isoform B - - GO:0004871//signal transducer activity - 35220 1742.00 10.18 11.46 0.17086948268121 Up 0.256273940034342 CG9987 CG9987 - - - - 37368 1724.00 1437.53 989.335 -0.5390610425094 Down 0.663122440892881 Act57B actin 57B K05692|1|0.0|762|dpe:Dper_GL17061|actin beta/gamma 1 - - - 7354411 2260.92 10.745 11.355 0.0796622232791043 Up 0.145654471007793 CG42380 CG42380, isoform B K05284|1|0.0|845|dme:Dmel_CG9865|phosphatidylinositol glycan, class M [EC:2.4.1.-] GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane GO:0016757//transferase activity, transferring glycosyl groups;GO:0016757//transferase activity, transferring glycosyl groups GO:0006497//protein lipidation;GO:0006497//protein lipidation 35235 4072.41 21.965 20.655 -0.0887154392366412 Down 0.193270373794743 swm second mitotic wave missing, isoform D K13192|1|0.0|1494|dme:Dmel_CG10084|RNA-binding protein 26 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0000278//mitotic cell cycle;GO:0008589//regulation of smoothened signaling pathway;GO:0000278//mitotic cell cycle;GO:0008589//regulation of smoothened signaling pathway 33157 2629.00 1.195 0.935 -0.353972348093112 Down 0.143210936468102 Ir21a ionotropic receptor 21a K06094|1|1e-68|261|dpe:Dper_GL13933|lethal giant larvae;K05202|2|8e-18|92.8|bfo:BRAFLDRAFT_128813|glutamate receptor, ionotropic, kainate 2;K05204|3|1e-16|88.6|mdo:100030869|glutamate receptor, ionotropic, kainate 4 GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 3772038 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 41157 1121.20 107.96 93.11 -0.213488855469084 Down 0.425703341698587 CG9399 CG9399, isoform E - - - - 39081 1010.00 178.77 200.79 0.167582766851661 Up 0.381323471139876 Cpr67B cuticular protein 67B - - GO:0005198//structural molecule activity - 43808 5409.52 88.285 97.495 0.143159893981862 Up 0.325914674415533 gw gawky, isoform J - - - - 37308 1826.11 0.415 0.66 0.669354688011529 Up 0.153711530841368 CG13870 CG13870, isoform B - - - - 49804 1520.78 60.705 54.645 -0.151725853926642 Down 0.329348831065909 Spn88Ea serpin 88Ea, isoform B K13963|1|3e-47|189|gga:420895|serpin B - GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity GO:0008592//regulation of Toll signaling pathway;GO:0008592//regulation of Toll signaling pathway 31475 2779.00 1.5 1.145 -0.389614902398937 Down 0.174514595165764 l(1)G0045 lethal (1) G0045 K01164|1|2e-86|321|ecb:100055680|ribonuclease P [EC:3.1.26.5] - - - 31865 1509.00 0.185 0.32 0.79054663437105 Up 0.119039756967376 Gr8a gustatory receptor 8a K08471|1|0.0|743|dme:Dmel_CG15371|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 39779 2570.60 2.95 3.265 0.146368037297227 Up 0.130365869766213 CG13055 CG13055, isoform B - - - - 35653 4757.68 12.965 16.805 0.374268336454707 Up 0.467375511821424 cos costa, isoform B K06227|1|0.0|2162|dme:Dmel_CG1708|costal 2;K10395|3|7e-34|147|spu:756355|kinesin family member 4/7/21/27 GO:0016020//membrane;GO:0005875//microtubule associated complex;GO:0012505//endomembrane system GO:0005102//receptor binding;GO:0032559;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0019900//kinase binding GO:0042992//negative regulation of transcription factor import into nucleus;GO:0007017//microtubule-based process;GO:0003006//developmental process involved in reproduction;GO:0007227//signal transduction downstream of smoothened;GO:0043392//negative regulation of DNA binding;GO:0010608//posttranscriptional regulation of gene expression;GO:0006508//proteolysis;GO:0008589//regulation of smoothened signaling pathway;GO:0007472//wing disc morphogenesis 12798010 2449.00 0.335 0.735 1.13358315437859 Up 0.223649451855765 39980 1326.00 6.175 5.75 -0.102877180640302 Down 0.134361378945978 CG32187 CG32187 - - - - 40243 1131.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 CG5665 CG5665, isoform C K01059|1|7e-175|612|dme:Dmel_CG5665|lipoprotein lipase [EC:3.1.1.34];K12591|3|1e-25|116|nvi:100113631|exosome complex exonuclease RRP6 [EC:3.1.13.-] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 34919 813.00 0.58 0.495 -0.228624375047962 Down 0.077895918636904 CG7631 CG7631 K08076|1|6e-38|157|cel:C05D11.6|astacin [EC:3.4.24.21];K01395|2|1e-34|146|cin:100181769|meprin A, alpha [EC:3.4.24.18];K08606|5|7e-33|140|ptr:468515|meprin A, beta [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33556 3359.25 22.855 25.535 0.159966240108381 Up 0.307059833575485 pgant2 polypeptide GalNAc transferase 2, isoform B K00710|1|0.0|1149|dsi:Dsim_GD22759|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0030246//carbohydrate binding;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0016740//transferase activity - 43736 2599.25 269.655 371.175 0.460984758073234 Up 0.631455554087967 Ef1alpha100E elongation factor 1alpha100E, isoform D K03231|1|0.0|908|dya:Dyak_GE10959|elongation factor EF-1 alpha subunit [EC:3.6.5.3] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation 19836011 560.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 33185 12243.83 44.695 50.5 0.176169940766192 Up 0.364548936732268 kis kismet, isoform F K04494|1|4e-22|108|mdo:100023377|chromodomain helicase DNA binding protein 8 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0006935//chemotaxis;GO:0006959//humoral immune response;GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0006935//chemotaxis;GO:0006959//humoral immune response;GO:0009880//embryonic pattern specification;GO:0007297//ovarian follicle cell migration;GO:0006935//chemotaxis;GO:0006959//humoral immune response 39654 4080.00 2.46 2.89 0.232411177161439 Up 0.166655659754326 Msh6 Msh6 K08737|1|0.0|2343|dme:Dmel_CG7003|DNA mismatch repair protein MSH6 - GO:0032559;GO:0003690//double-stranded DNA binding GO:0006298//mismatch repair 40975 1223.00 0.52 0.19 -1.45251220469751 Down 0.20921938977678 ato atonal K09083|1|2e-126|452|dme:Dmel_CG7508|atonal protein 1/7 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0007417//central nervous system development;GO:0048812//neuron projection morphogenesis;GO:0001742//oenocyte differentiation;GO:0001752//compound eye photoreceptor fate commitment;GO:0010468//regulation of gene expression;GO:0008049//male courtship behavior;GO:0043704//photoreceptor cell fate specification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050954//sensory perception of mechanical stimulus;GO:0008037//cell recognition;GO:0001709//cell fate determination;GO:0007560//imaginal disc morphogenesis;GO:0000165//MAPK cascade 31869 6060.00 2.95 3.125 0.0831412353002456 Up 0.0839717342491084 mxc multi sex combs, isoform B - - - GO:0019538//protein metabolic process 19834868 562.00 0.01 0.165 4.04439411935845 Up 0.184883106590939 19835797 704.00 0.29 0.01 -4.85798099512757 Down 0.265024435345397 41228 1512.00 4.79 5.935 0.309222373905727 Up 0.295139347510236 mtTFB2 mitochondrial transcription factor B2 - GO:0031980 GO:0008173//RNA methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0008134//transcription factor binding GO:0000154//rRNA modification;GO:0006351//transcription, DNA-dependent 49847 1938.00 10.19 10.975 0.107066888256907 Up 0.180458327829877 Cyp6a22 Cyp6a22, isoform C K00517|1|0.0|964|dme:Dmel_CG10240| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 19835337 440.00 0.77 0.235 -1.71219768901726 Down 0.277242108043852 326184 2362.00 19.015 24.76 0.380873375583673 Up 0.509344868577467 CG32052 CG32052 K01128|1|0.0|950|dme:Dmel_CG32052| [EC:3.1.4.-] - GO:0003824//catalytic activity - 14462875 3318.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 CG43954 CG43954 - - - - 43334 3208.36 12.685 10.36 -0.292099516377385 Down 0.377691190067362 Ets98B Ets at 98B, isoform B K09442|1|0.0|840|dme:Dmel_CG5583|SAM pointed domain-containing ETS transcription factor GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007276//gamete generation;GO:0006351//transcription, DNA-dependent 33076 1109.42 29.065 30.21 0.055743275496055 Up 0.154239862633734 CG1532 CG1532, isoform B - - - - 31622 2522.00 5.51 5.22 -0.0780025120012729 Down 0.106260731739532 Nf-YC nuclear factor Y-box C K08066|1|2e-37|158|tca:655290|nuclear transcription factor Y, gamma - - - 42757 3531.80 4.83 4.56 -0.0829893646710316 Down 0.102958658037247 pnt pointed, isoform E K02678|1|0.0|865|dme:Dmel_CG17077|c-ets proto-oncogene protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003677//DNA binding GO:0006909//phagocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0003006//developmental process involved in reproduction;GO:0001752//compound eye photoreceptor fate commitment;GO:0010468//regulation of gene expression;GO:0016337//cell-cell adhesion;GO:0042685//cardioblast cell fate specification;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006350;GO:0007264//small GTPase mediated signal transduction;GO:0060446//branching involved in open tracheal system development;GO:0007445;GO:0042051//compound eye photoreceptor development;GO:0002682//regulation of immune system process;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006909//phagocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0003006//developmental process involved in reproduction;GO:0001752//compound eye photoreceptor fate commitment;GO:0010468//regulation of gene expression;GO:0016337//cell-cell adhesion;GO:0042685//cardioblast cell fate specification;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006350;GO:0007264//small GTPase mediated signal transduction;GO:0060446//branching involved in open tracheal system development;GO:0007445;GO:0042051//compound eye photoreceptor development;GO:0002682//regulation of immune system process;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0006909//phagocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0003006//developmental process involved in reproduction;GO:0001752//compound eye photoreceptor fate commitment;GO:0010468//regulation of gene expression;GO:0042685//cardioblast cell fate specification;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006350;GO:0007264//small GTPase mediated signal transduction;GO:0060446//branching involved in open tracheal system development;GO:0007445;GO:0042051//compound eye photoreceptor development;GO:0002682//regulation of immune system process;GO:0007472//wing disc morphogenesis;GO:0043066//negative regulation of apoptotic process 50044 3916.18 10.995 12.16 0.145295624588617 Up 0.235239730550786 CG17193 CG17193, isoform C - - - - 34716 2180.59 135.205 116.99 -0.2087632874697 Down 0.429368643508123 Pect phosphoethanolamine cytidylyltransferase, isoform E K00967|1|0.0|729|dsi:Dsim_GD23872|ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14] - GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006066//alcohol metabolic process;GO:0006066//alcohol metabolic process;GO:0006066//alcohol metabolic process;GO:0006066//alcohol metabolic process 38546 1536.00 165.405 70.83 -1.2235703987544 Down 0.746929071456875 CG15021 CG15021 K05312|1|5e-06|52.8|dsi:Dsim_GD13845|nicotinic acetylcholine receptor, invertebrate - - - 38572 1142.00 1.045 0.9 -0.215506035751208 Down 0.0953969092590147 CG18418 CG18418 K13577|1|4e-43|175|aga:AgaP_AGAP003074|mitochondrial dicarboxylate carrier;K03454|2|1e-42|174|dre:393133|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0015140//malate transmembrane transporter activity GO:0046907//intracellular transport;GO:0015740//C4-dicarboxylate transport 39857 465.00 21.655 23.735 0.132315877361864 Up 0.262085589750363 CG4101 CG4101 - GO:0031224//intrinsic to membrane - - 14462547 943.00 0.085 0.155 0.866733469136535 Up 0.0881983885880333 326161 4455.74 11.73 11.655 -0.00925400889964213 Down 0.0513802668075551 CG31793 CG31793, isoform C K01509|1|0.0|2484|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3];K05673|2|0.0|1548|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0015405;GO:0005253//anion channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 40045 5605.80 16.14 18.89 0.226982123110589 Up 0.362237485140668 ftz-f1 ftz transcription factor 1, isoform C K08705|1|0.0|937|dme:Dmel_CG4059|nuclear receptor subfamily 5 group A member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding GO:0002165//instar larval or pupal development;GO:0007635//chemosensory behavior;GO:0003002//regionalization;GO:0009719;GO:0010468//regulation of gene expression;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0009653//anatomical structure morphogenesis;GO:0002165//instar larval or pupal development;GO:0007635//chemosensory behavior;GO:0003002//regionalization;GO:0009719;GO:0010468//regulation of gene expression;GO:0050793//regulation of developmental process;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0009653//anatomical structure morphogenesis 40304 1065.00 10.345 14.28 0.46506233416909 Up 0.498943336415269 Mst77F Male-specific transcript 77F - GO:0042995//cell projection - GO:0006323//DNA packaging 35667 1866.48 15.035 13.715 -0.132570245725726 Down 0.233093382644301 kappaB-Ras kappaB-Ras, isoform C K01047|1|3e-33|143|dme:Dmel_CG11124|phospholipase A2 [EC:3.1.1.4] GO:0044464//cell part;GO:0044464//cell part GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity;GO:0032561//guanyl ribonucleotide binding;GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity;GO:0032561//guanyl ribonucleotide binding GO:0006629//lipid metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0019637//organophosphate metabolic process 19835108 7420.00 0.41 0.38 -0.109624491174498 Down 0.052073702285035 246422 596.00 1.3 2.08 0.678071905112638 Up 0.284209483555673 CG30056 CG30056 - GO:0031224//intrinsic to membrane - - 40326 587.00 12.21 12.68 0.0544915451520039 Up 0.114119667150971 CG10581 CG10581 - - GO:0016462//pyrophosphatase activity;GO:0032559 - 35685 2909.00 6.675 8.235 0.303000813151439 Up 0.331660282657509 CG2144 CG2144 K05310|1|0.0|1664|dme:Dmel_CG2144|ethanolaminephosphotransferase [EC:2.7.-.-] - - - 19834776 1390.00 0.725 0.455 -0.672114449816238 Down 0.160645885616167 31929 925.56 4.045 3.15 -0.360787874042699 Down 0.271133271694624 CG43386 CG43386, isoform D - - - - 35331 1120.50 2.285 2.25 -0.0222691638410328 Down 0.0488046493197728 CG2617 CG2617, isoform B K10604|1|5e-07|55.8|ptr:453884|E3 ubiquitin-protein ligase MGRN1 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 35061 12202.00 0.225 0.355 0.657894023175007 Up 0.11121384229296 Dhc36C dynein heavy chain at 36C K10408|1|0.0|3517|tgu:100230839|dynein heavy chain, axonemal GO:0030286//dynein complex;GO:0005930//axoneme GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0032559 GO:0006071//glycerol metabolic process;GO:0048870//cell motility;GO:0007017//microtubule-based process 34713 4427.83 96.495 107.17 0.151375015489597 Up 0.342656188086118 CG16974 CG16974, isoform B K13023|1|4e-29|131|rno:303861|carboxypeptidase N regulatory subunit - GO:0005488//binding - 3772419 1631.00 14.98 16.96 0.179098546104448 Up 0.300356623959847 CG18065 CG18065 K01312|1|3e-45|182|dme:Dmel_CG18444|trypsin [EC:3.4.21.4];K09635|4|2e-43|177|mmu:214523|transmembrane protease, serine 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31179 3796.98 73.895 88.155 0.254565649280496 Up 0.464601769911504 Unc-76 Unc-76, isoform D - - - - 44481 241.00 10.86 148.64 3.77472639857829 Up 0.848963148857482 Met75Cb Met75Cb - - - - 8674022 533.00 0.475 0.53 0.158064846232252 Up 0.0673292827895919 CG14397 CG14397 - - - - 39781 434.00 63.085 71.37 0.178020762493169 Up 0.376568485008585 CG13071 CG13071 - - - - 31215 3262.48 43.105 47.61 0.143409403273108 Up 0.307522123893805 CG2918 CG2918, isoform B K09486|1|0.0|1530|dme:Dmel_CG2918|hypoxia up-regulated 1 GO:0044444//cytoplasmic part GO:0032559 - 43459 675.00 172.325 185.2 0.103952083282162 Up 0.260566635847312 CG1458 CG1458 - GO:0031224//intrinsic to membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding - 37038 5493.97 16.64 11.295 -0.558971162748008 Down 0.553262448817858 grh grainy head, isoform P K09275|1|0.0|1285|der:Dere_GG21828|transcription factor CP2 and related proteins - - - 43117 680.00 1.345 1.78 0.404271068409774 Up 0.193732664113063 CG5024 CG5024, isoform B K02183|1|1e-24|112|spu:591003|calmodulin - GO:0046872//metal ion binding;GO:0046872//metal ion binding - 34703 4007.00 0.72 1.225 0.766712937560258 Up 0.233852859595826 CG5122 CG5122 K00624|1|0.0|2279|dme:Dmel_CG5122|carnitine O-acetyltransferase [EC:2.3.1.7] - GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 41672 1226.00 19.85 15.1 -0.394590457817879 Down 0.495046889446572 CG9588 CG9588 K06693|1|4e-121|434|dme:Dmel_CG9588|26S proteasome non-ATPase regulatory subunit 9 - - - 38525 523.00 0.98 1.49 0.604458676346953 Up 0.223847576277903 srw shrew K01810|1|2e-14|77.4|bmy:Bm1_47625|glucose-6-phosphate isomerase [EC:5.3.1.9] - - GO:0008344//adult locomotory behavior 34946 3018.00 0.54 1.095 1.0198995574377 Up 0.260401532162198 BicC bicaudal C, isoform D - GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0017148//negative regulation of translation;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0017148//negative regulation of translation;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0017148//negative regulation of translation;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation 37108 755.00 104.9 61.275 -0.775644193710428 Down 0.696341302337868 GstE3 glutathione S transferase E3 K00799|1|8e-124|442|dme:Dmel_CG17524|glutathione S-transferase [EC:2.5.1.18] - - - 246563 1525.00 2.24 1.925 -0.218640286475341 Down 0.142517500990622 CG30357 CG30357 K10456|1|1e-10|67.8|isc:IscW_ISCW010216|kelch-like protein 19;K10463|2|1e-09|64.7|mcc:719583|kelch-like protein 26;K13956|4|2e-09|63.9|bfo:BRAFLDRAFT_122670|actin-binding protein IPP;K10444|5|2e-09|63.9|mmu:239743|kelch-like protein 6 GO:0031224//intrinsic to membrane GO:0005488//binding GO:0051234//establishment of localization 32070 5830.00 21.08 25.43 0.270656595052892 Up 0.425835424646678 CG1657 CG1657 - GO:0044444//cytoplasmic part GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity GO:0051049//regulation of transport;GO:0009966//regulation of signal transduction 32553 2011.25 11.44 8.91 -0.360589715256468 Down 0.415169726588297 CG8916 CG8916, isoform C K05270|1|0.0|972|dme:Dmel_CG8916|gamma-aminobutyric acid (GABA) receptor, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0015276//ligand-gated ion channel activity;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0016917//GABA receptor activity GO:0006810//transport;GO:0006810//transport 38157 1804.46 9.96 7.52 -0.405413080390444 Down 0.422302205785233 CG2211 CG2211, isoform B - - - - 14462490 593.24 0.01 0.385 5.2667865406949 Up 0.314357416457535 31749 1253.00 0.31 0.58 0.903784684740697 Up 0.172632413155462 CG10761 CG10761 K10660|1|1e-166|586|dme:Dmel_CG10761|E3 ubiquitin-protein ligase MARCH5 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 34431 2896.00 30.85 39.48 0.355851500419618 Up 0.528166688680491 CG5337 CG5337 K11452|1|1e-56|221|tgu:100222038|chromobox protein 4;K13136|2|2e-44|181|nvi:100114269|gem associated protein 8 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 19836234 1614.00 20.395 24.72 0.277463236111851 Up 0.432967903843614 41849 953.00 8.93 11.84 0.406937000507727 Up 0.445647866860388 CG4338 CG4338 K09140|1|7e-131|466|dme:Dmel_CG4338|hypothetical protein - - - 34517 745.41 75.86 79.28 0.0636175908922507 Up 0.173953242636376 CG16743 CG16743, isoform B - - - - 31948 6457.00 13.515 18.29 0.436493563214022 Up 0.511524237220975 CG43902 CG43902 - - - - 35490 1236.07 10.345 10.435 0.0124969552998252 Up 0.053625676925109 CG10395 CG10395, isoform C K11666|1|0.0|637|dme:Dmel_CG10395|INO80 complex subunit B - - - 31185 1678.14 146.005 71.555 -1.02889328981807 Down 0.732102760533615 Pgd phosphogluconate dehydrogenase, isoform B K00033|1|0.0|945|dme:Dmel_CG3724|6-phosphogluconate dehydrogenase [EC:1.1.1.44] - - - 40576 2119.34 91.595 98.025 0.0978808902983129 Up 0.252245410117554 CG9775 CG9775, isoform E - - - - 48775 2160.00 9.68 10.54 0.12279591436262 Up 0.192147668735966 Pgant35A polypeptide N-acetylgalactosaminyltransferase 35A K00710|1|0.0|1273|dme:Dmel_CG7480|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0060541//respiratory system development;GO:0009311//oligosaccharide metabolic process 34736 4106.23 85.46 92.33 0.111550169628037 Up 0.270670981376304 CG31729 CG31729, isoform D K01530|1|0.0|2051|dya:Dyak_GE18642|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559 GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport 31674 2069.22 47.21 37.315 -0.339336796818296 Down 0.525095760137366 CG9657 CG9657, isoform B K03307|1|4e-163|575|dme:Dmel_CG6723|solute:Na+ symporter, SSS family - - - 39941 719.00 6.12 7.62 0.31625934480067 Up 0.333443402456743 CG33051 CG33051 K03024|1|3e-81|300|dme:Dmel_CG33051|DNA-directed RNA polymerase III subunit C31 [EC:2.7.7.6] - - - 40349 900.00 81.595 85.46 0.0667685679621381 Up 0.19231277242108 ppl pumpless K02437|1|7e-72|270|dpo:Dpse_GA20566|glycine cleavage system H protein GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0006546//glycine catabolic process 40325 1617.64 6.745 6.615 -0.0280772866695908 Down 0.0667349095231806 Sin Sex-lethal interactor, isoform C - GO:0030532//small nuclear ribonucleoprotein complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0034062//RNA polymerase activity;GO:0034062//RNA polymerase activity GO:0000377;GO:0000377 36353 650.00 38.365 138.94 1.85659934243044 Up 0.779289393739268 Cpr49Ag cuticular protein 49Ag - - GO:0005198//structural molecule activity - 37259 1250.00 0.86 1.33 0.629017680799092 Up 0.216186765288601 CG11018 CG11018 - - - - 35787 1957.05 7.89 10.465 0.407475106242251 Up 0.429731871615374 Pbp49 PSEA-binding protein 49kD, isoform D - GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding GO:0006383//transcription from RNA polymerase III promoter;GO:0034622;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0034622;GO:0006366//transcription from RNA polymerase II promoter 34586 1218.00 1.225 1.365 0.156119201917282 Up 0.0909721304979527 CG4988 CG4988 K01785|1|0.0|730|dme:Dmel_CG4988|aldose 1-epimerase [EC:5.1.3.3] - GO:0005488//binding;GO:0003824//catalytic activity GO:0005996//monosaccharide metabolic process 14462432 413.00 0.21 0.235 0.162271428898877 Up 0.0554418174613657 41392 1574.76 118.1 136.935 0.213482275672389 Up 0.429996037511557 Jupiter jupiter, isoform I - GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0015631//tubulin binding;GO:0005198//structural molecule activity GO:0031112;GO:0031112;GO:0031112;GO:0031112;GO:0031112;GO:0031112 42655 1694.00 80.09 58.09 -0.463332289791194 Down 0.609463743230749 CG5326 CG5326 K10250|1|5e-65|248|cfa:608997|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane - - 318785 1228.00 3.71 5 0.430508908041284 Up 0.334301941619337 CG31528 CG31528 K04523|1|1e-26|120|hmg:100211830|ubiquilin - - - 318220 803.00 0.49 1.055 1.10638934459198 Up 0.267401928411042 CG32806 CG32806 - - - - 14462837 6153.00 77.36 161.995 1.06628958487062 Up 0.735602958658037 CG44195 CG44195 - - - - 31778 3067.00 0.06 0.03 -1 Down 0.0654471007792894 org-1 optomotor-blind-related-gene-1, isoform B K10175|1|4e-80|299|xla:735223|T-box protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter 32300 1480.35 39.575 42.32 0.0967502770894822 Up 0.23517368907674 CG1998 CG1998, isoform C K07750|1|1e-171|602|dme:Dmel_CG1998|methylsterol monooxygenase [EC:1.14.13.72] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process 35614 1394.00 212.975 164.055 -0.376504525723936 Down 0.587207766477348 Tsp42Ee tetraspanin 42Ee, isoform B K06497|1|3e-35|149|dan:Dana_GF13154|CD63 antigen GO:0044444//cytoplasmic part;GO:0016020//membrane - - 48632 1574.47 220.08 130.285 -0.756357051968316 Down 0.703374719323735 Act87E actin 87E, isoform C K05692|1|0.0|762|dvi:Dvir_GJ10425|actin beta/gamma 1 GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015629//actin cytoskeleton GO:0008194//UDP-glycosyltransferase activity;GO:0005198//structural molecule activity;GO:0032559;GO:0008194//UDP-glycosyltransferase activity;GO:0005198//structural molecule activity;GO:0032559 GO:0006024//glycosaminoglycan biosynthetic process;GO:0006996//organelle organization;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0051301//cell division;GO:0030166//proteoglycan biosynthetic process;GO:0048513//organ development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006996//organelle organization;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0051301//cell division;GO:0030166//proteoglycan biosynthetic process;GO:0048513//organ development 39333 1431.00 24.35 17.85 -0.447997698053242 Down 0.544379870558711 CG10361 CG10361 K00639|1|0.0|786|dme:Dmel_CG10361|glycine C-acetyltransferase [EC:2.3.1.29] GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0048037//cofactor binding;GO:0016453 GO:0006519 318728 1779.00 0.025 0.055 1.13750352374994 Up 0.0654471007792894 Ir94b ionotropic receptor 94b - - - - 38946 3164.91 98.715 171.225 0.794552132582969 Up 0.705124818385946 CG17352 CG17352, isoform E - - - - 43288 5398.00 10.06 10.01 -0.00718833096953342 Down 0.0492999603751156 l(3)mbt lethal (3) malignant brain tumor K11465|1|2e-33|145|tgu:100228898|sex comb on midleg-like protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048513//organ development;GO:0001700//embryonic development via the syncytial blastoderm;GO:0009794//regulation of mitotic cell cycle, embryonic 14462451 539.00 0.395 0.27 -0.548893246013634 Down 0.10530313036587 41035 2780.06 12.87 14.975 0.218543949455446 Up 0.331164971602166 CG8116 CG8116, isoform C - - - - 43636 2679.00 11.34 13.695 0.272228625763149 Up 0.368907674019284 CG9717 CG9717 K03321|1|1e-34|148|rno:64076|sulfate permease, SulP family;K04602|2|8e-32|139|gga:416011|cadherin EGF LAG seven-pass G-type receptor 3 (flamingo);K13962|3|7e-29|129|tgu:100223009|solute carrier family 26 (sulfate anion transporter), member 7 GO:0031224//intrinsic to membrane - GO:0006810//transport 33109 6296.69 22.785 31.02 0.445114315812851 Up 0.561484612336547 tty tweety, isoform G - - - - 37479 3343.71 13.42 18.18 0.437967527993924 Up 0.511425175009906 CG17922 cyclic nucleotide-gated ion channel subunit B, isoform B K05326|1|1e-121|438|cel:F36F2.5|cyclic nucleotide gated channel, invertebrate;K04952|2|2e-111|404|cfa:611173|cyclic nucleotide gated channel beta 1 GO:0034703//cation channel complex GO:0015075//ion transmembrane transporter activity GO:0006810//transport 40800 4651.00 16.06 19.905 0.309658978574035 Up 0.441520274732532 dpr11 dpr11, isoform C K06772|1|6e-08|60.5|ecb:100061094|limbic system-associated membrane protein - - - 37140 1273.00 11.62 9.51 -0.289092822543966 Down 0.366365077268525 CG5335 CG5335 K06832|1|9e-19|94.7|dre:337597|galectin-8;K06831|2|3e-18|93.2|dre:327284|galectin-3;K10091|4|2e-11|70.1|xtr:496937|galectin-4;K10093|5|5e-11|68.9|bta:510813|galectin-9 - - - 31379 5087.72 4.225 5.33 0.335184191589629 Up 0.29738475762779 bi bifid, isoform G K10177|1|3e-104|380|xtr:613116|T-box protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0008168//methyltransferase activity GO:0007472//wing disc morphogenesis;GO:0006544//glycine metabolic process;GO:0010468//regulation of gene expression;GO:0040007//growth;GO:0048592//eye morphogenesis;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0051180//vitamin transport 32952 2338.00 0.495 0.64 0.370643379920391 Up 0.111015717870823 CG14205 CG14205 K00680|1|2e-174|612|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 43531 1356.98 21 18.685 -0.16850876417274 Down 0.305672962620526 CG15514 CG15514, isoform B - GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - 3772603 1175.00 2.09 4.065 0.959752409994145 Up 0.457568352925637 CG15892 CG15892 - - - - 317854 544.00 0.305 0.47 0.623851514114751 Up 0.122110685510501 CG32102 CG32102 - - - - 41596 1462.00 40.375 31.66 -0.350801004331468 Down 0.523543785497292 yellow-f2 yellow-f2 - - - - 19834856 394.00 0.355 0.675 0.927068477546149 Up 0.191091005151235 59233 458.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 CG13713 CG13713 - - - - 41630 1100.00 0.04 0.01 -2 Down 0.0694426099590543 CG15888 CG15888 - - - - 4379842 972.61 3.975 4.305 0.115058377225126 Up 0.126073173953243 CG34112 CG34112, isoform D - - - - 53448 2654.35 3.86 3.385 -0.189445013693084 Down 0.169924712719588 meso18E meso18E, isoform D - - - - 3772530 316.00 1.01 0.76 -0.410283969308209 Down 0.143739268260468 43073 1700.00 0.425 0.52 0.29104878200339 Up 0.0859199577334566 CG11913 CG11913 K03935|1|0.0|1060|dme:Dmel_CG11913|NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3] - GO:0016491//oxidoreductase activity;GO:0000166//nucleotide binding;GO:0048037//cofactor binding GO:0006091//generation of precursor metabolites and energy 40340 697.94 21.55 25.815 0.260521728784899 Up 0.416886804913486 CG33054 CG33054, isoform B - - - - 36931 1279.00 0.305 0.27 -0.175849835399418 Down 0.0562343151499141 Spn53F serpin 53F K13963|1|9e-38|157|dpo:Dpse_GA10637|serpin B - - - 19835511 796.00 0.105 0.17 0.695145418471579 Up 0.0806696605468234 41822 1483.00 3.025 2.19 -0.466004272560783 Down 0.27780346057324 CG3987 CG3987 - - - - 3885587 1610.00 0.31 0.035 -3.14684138832927 Down 0.218201030246995 CG33465 CG33465 K09632|1|1e-17|91.3|dre:447843|chymotrypsin-like protease [EC:3.4.21.-];K01319|2|3e-17|90.1|ssc:100154047|cathepsin G [EC:3.4.21.20];K01310|3|8e-17|88.6|xtr:496968|chymotrypsin [EC:3.4.21.1];K09641|5|2e-16|87.0|ecb:100067298|transmembrane protease, serine 11D [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42282 648.00 225.35 250.995 0.15549117489149 Up 0.367256637168142 NP15.6 NP15.6 K11351|1|1e-09|62.8|dre:562219|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 [EC:1.6.5.3 1.6.99.3] - - - 39460 1579.29 116.71 129.39 0.148797941903594 Up 0.3452318055739 Wbp2 Wbp2 ortholog, isoform G - - - - 19836174 455.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 3346201 11074.81 28.27 20.565 -0.459080811330793 Down 0.560394928014793 Unc-89 Unc-89, isoform H K12567|1|2e-136|489|ecb:100053844|titin [EC:2.7.11.1] GO:0044464//cell part;GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004672//protein kinase activity;GO:0032559;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0007266//Rho protein signal transduction;GO:0006464//cellular protein modification process;GO:0007266//Rho protein signal transduction 38249 1653.39 51.855 67.75 0.385737842145041 Up 0.569211464799894 CG13937 CG13937, isoform I K01017|1|1e-26|121|gga:418081|chondroitin 4-sulfotransferase 11 [EC:2.8.2.5] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process 36255 3212.00 7.98 9.96 0.319756995845735 Up 0.371054021925769 pyr pyramus - - - GO:0048731 318273 1037.00 0.08 0.045 -0.830074998557688 Down 0.0697397965922599 CG32987 CG32987 - - - - 34769 835.00 0.145 0.37 1.35147237050138 Up 0.165400871747457 CG16852 CG16852 - - - - 41921 4744.00 17.815 19.78 0.150949942625812 Up 0.277077004358737 cv-d crossveinless d K13211|1|2e-85|318|nvi:100114520|GC-rich sequence DNA-binding factor - - - 41977 1581.00 0.1 0.06 -0.736965594166207 Down 0.0694426099590543 CG6901 CG6901 K07299|1|2e-08|60.5|gga:396130|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1;K07191|3|4e-07|56.2|ecb:100033939|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4;K08149|5|7e-07|55.5|tgu:100221849|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 12 - - - 37846 751.83 861.13 648.48 -0.409168969201251 Down 0.610355303130366 eIF-5A eIF-5A, isoform B K03263|1|7e-88|323|dme:Dmel_CG3186|translation initiation factor eIF-5A GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006448//regulation of translational elongation;GO:0006449//regulation of translational termination;GO:0018205//peptidyl-lysine modification;GO:0048102//autophagic cell death;GO:0006448//regulation of translational elongation;GO:0006449//regulation of translational termination;GO:0018205//peptidyl-lysine modification;GO:0048102//autophagic cell death 14462915 3103.00 0.04 0.2 2.32192809488736 Up 0.151135913353586 CG43968 CG43968 - - - - 42793 4914.22 12.87 16.24 0.335539578964474 Up 0.44254391758024 CG10254 CG10254, isoform C K10581|1|0.0|2536|dme:Dmel_CG10254|ubiquitin-conjugating enzyme E2 O [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity;GO:0016881//acid-amino acid ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process 38638 5864.89 13.445 13.015 -0.0468944434687608 Down 0.110718531237617 Blimp-1 Blimp-1, isoform F K09228|1|8e-40|166|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0007424//open tracheal system development 3772383 610.42 29.95 35.26 0.235476471644034 Up 0.416556597543257 CG15891 CG15891, isoform D - - - - 3355134 3459.11 29.88 31.08 0.0568063556184727 Up 0.155560692114648 CG17528 CG17528, isoform D K08805|1|0.0|1349|dse:Dsec_GM11705|doublecortin and CaM kinase-like 1 [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0004672//protein kinase activity;GO:0015631//tubulin binding;GO:0032559;GO:0004672//protein kinase activity;GO:0015631//tubulin binding;GO:0032559 GO:0006464//cellular protein modification process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023033 19835479 1736.00 2.605 2.98 0.194028958183653 Up 0.151234975564655 41259 2311.83 18.37 17.695 -0.0540098646861191 Down 0.125842028794083 CG6293 CG6293, isoform B - GO:0044464//cell part - GO:0006810//transport 246540 648.00 2.9 3.75 0.370837695368309 Up 0.267302866199974 CG30324 CG30324 - - - - 31554 1116.45 107.875 113.875 0.0780904946230957 Up 0.214700832122573 sqh spaghetti squash, isoform E K12759|1|2e-85|316|dvi:Dvir_GJ16661|myosin regulatory light chain, invertebrate - - - 38466 607.00 0.07 0.08 0.192645077942396 Up 0.045898824461762 CG14983 CG14983 K08849|1|7e-07|53.5|mmu:234736|mixed lineage kinase domain-like [EC:2.7.11.1] - GO:0046914//transition metal ion binding - 42483 987.00 17.105 6.825 -1.32551715296069 Down 0.686071853123762 CG5697 CG5697, isoform D K05849|1|4e-12|72.0|dpe:Dper_GL24292|solute carrier family 8 (sodium/calcium exchanger) - - - 3771951 736.62 338.625 354.74 0.0670735273490165 Up 0.202978470479461 Prx5 peroxiredoxin 5, isoform B K11187|1|6e-104|377|dme:Dmel_CG7217|peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15] GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0006950//response to stress;GO:0019725//cellular homeostasis;GO:0006950//response to stress;GO:0019725//cellular homeostasis 39389 4014.00 7.295 8.24 0.175736359265327 Up 0.23041870294545 Rh7 rhodopsin 7 K04255|1|8e-49|196|bfo:BRAFLDRAFT_65960|opsin 4 (melanopsin);K13802|2|1e-45|186|dse:Dsec_GM26888|opsin Rh1 GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction 36485 4681.00 0.255 0.635 1.31625934480067 Up 0.2242768458592 CG4744 CG4744 K01137|1|0.0|1196|dsi:Dsim_GD25763|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14];K03243|3|9e-07|57.0|aag:AaeL_AAEL009241|translation initiation factor IF-2 unclassified subunit - GO:0016788//hydrolase activity, acting on ester bonds - 39869 668.00 0.01 0.245 4.61470984411521 Up 0.239499405626734 PGRP-SB2 PGRP-SB2, isoform B K01446|1|1e-95|348|dme:Dmel_CG9697|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0002376//immune system process 19835069 474.00 3.385 3.315 -0.030146963462409 Down 0.0565975432571655 39726 802.95 53.625 55.58 0.0516600919262916 Up 0.148890503236032 CG15715 CG15715, isoform B - GO:0044464//cell part GO:0046914//transition metal ion binding - 42620 2046.80 730.08 689.025 -0.0834982294910265 Down 0.225894861973319 PyK pyruvate kinase, isoform B K00873|1|0.0|938|dme:Dmel_CG7070|pyruvate kinase [EC:2.7.1.40] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0031420;GO:0016301//kinase activity;GO:0031420;GO:0016301//kinase activity GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 5740836 446.00 2.55 1.36 -0.906890595608518 Down 0.368874653282261 CG34273 CG34273 - - - - 44258 7716.11 97.85 116.125 0.247034840643211 Up 0.470017170783252 ps pasilla, isoform T K13162|1|3e-17|90.9|tgu:100221119|poly(rC)-binding protein 2/3/4;K13210|3|1e-16|89.0|api:100165913|far upstream element-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377 35855 1629.00 14.75 10.915 -0.434402824145775 Down 0.485437854972923 CG8738 CG8738 K01344|1|5e-36|152|gga:395085|protein C (activated) [EC:3.4.21.69];K09632|2|7e-35|148|gga:427531|chymotrypsin-like protease [EC:3.4.21.-];K01310|3|1e-33|144|xla:444360|chymotrypsin [EC:3.4.21.1];K01312|4|3e-32|139|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462905 864.00 0.275 0.155 -0.827163403137784 Down 0.111478008189143 39787 694.00 0.12 0.07 -0.777607578663552 Down 0.0762779025227843 CG13050 CG13050 - - - - 36624 1058.00 7.92 6.36 -0.316473664795254 Down 0.33839651301017 CG10131 CG10131 K13247|1|8e-174|609|dme:Dmel_CG10131|L-gulonate 3-dehydrogenase [EC:1.1.1.45] - GO:0051287//NAD binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0032787//monocarboxylic acid metabolic process 42927 5526.00 3.125 1.86 -0.748553568441418 Down 0.367950072645621 ana1 anastral spindle 1, isoform C - GO:0005813//centrosome;GO:0005813//centrosome - GO:0000278//mitotic cell cycle;GO:0048858//cell projection morphogenesis;GO:0048870//cell motility;GO:0051297//centrosome organization;GO:0048468//cell development;GO:0003006//developmental process involved in reproduction;GO:0000278//mitotic cell cycle;GO:0048858//cell projection morphogenesis;GO:0048870//cell motility;GO:0051297//centrosome organization;GO:0048468//cell development;GO:0003006//developmental process involved in reproduction 19835343 1048.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 33726 6375.72 38.575 35.355 -0.125751897486774 Down 0.283615110289262 vkg viking, isoform C K06237|1|0.0|1021|dme:Dmel_CG4145|collagen, type IV, alpha GO:0044444//cytoplasmic part;GO:0005604//basement membrane GO:0005198//structural molecule activity GO:0014706//striated muscle tissue development;GO:0048598//embryonic morphogenesis 8674094 456.00 24.745 14.275 -0.793646296616798 Down 0.643640206049399 Sfp24Bb seminal fluid protein 24Bb - - - - 35886 2285.42 320.01 284.65 -0.16892788889918 Down 0.384823669264298 Pgi phosphoglucose isomerase, isoform C K01810|1|0.0|1123|dme:Dmel_CG8251|glucose-6-phosphate isomerase [EC:5.3.1.9] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 34625 942.83 39.71 36.705 -0.113525758723922 Down 0.253004887069079 RpL7-like ribosomal protein L7-like, isoform C K02937|1|5e-144|510|dme:Dmel_CG5317|large subunit ribosomal protein L7e GO:0033279;GO:0033279 GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 53577 1073.38 5.755 6.795 0.239657622635161 Up 0.259873200369832 Jafrac2 thioredoxin peroxidase 2, isoform C K03386|1|2e-131|468|dsi:Dsim_GD13721|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] - GO:0004601//peroxidase activity;GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0033554//cellular response to stress;GO:0012502//induction of programmed cell death;GO:0019725//cellular homeostasis;GO:0042743//hydrogen peroxide metabolic process;GO:0033554//cellular response to stress;GO:0012502//induction of programmed cell death;GO:0019725//cellular homeostasis 40361 4228.60 46.71 51.16 0.131284819081444 Up 0.293851538766345 CG7324 CG7324, isoform B K11837|1|3e-14|82.0|hsa:9098|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15] GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0046872//metal ion binding GO:0032318//regulation of Ras GTPase activity 36378 1940.00 2.65 1.71 -0.631996034564664 Down 0.306366398098006 Cyp301a1 Cyp301a1 K00517|1|0.0|1118|dme:Dmel_CG8587| [EC:1.14.-.-];K10721|5|2e-50|201|dpo:Dpse_GA11350|CYP302A1; ecdysteroid 22-hydroxylase GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 35536 1414.00 6.99 6.095 -0.197666234755224 Down 0.232730154537049 CG7845 CG7845, isoform B - - - - 32880 903.73 98.535 81.94 -0.266068373451129 Down 0.48702285035002 CG7322 CG7322, isoform C K00120|1|4e-124|444|dme:Dmel_CG7322| [EC:1.1.-.-];K03331|2|2e-49|195|mmu:67880|L-xylulose reductase [EC:1.1.1.10] GO:0042995//cell projection GO:0005488//binding;GO:0016491//oxidoreductase activity GO:0019321//pentose metabolic process;GO:0046496//nicotinamide nucleotide metabolic process 42015 1283.00 206.1 210.545 0.0307841100700838 Up 0.114647998943336 Scp2 sarcoplasmic calcium-binding protein 2 - - - - 318952 2057.00 0.28 0.43 0.618909832644494 Up 0.117685906749439 CG31805 CG31805, isoform D - - - - 12798483 2301.00 7.18 7.065 -0.023294283489112 Down 0.0611544049663188 36203 1681.00 12.485 13.775 0.141856497530308 Up 0.238211596882842 dare defective in the avoidance of repellents K00528|1|0.0|926|dme:Dmel_CG12390|ferredoxin--NADP+ reductase [EC:1.18.1.2] GO:0031980 GO:0008937//ferredoxin-NAD(P) reductase activity GO:0007635//chemosensory behavior;GO:0018988;GO:0007617//mating behavior;GO:0019748//secondary metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0008203//cholesterol metabolic process 30977 1055.00 3.12 5.39 0.788739243890257 Up 0.467177387399287 CG12470 CG12470 - - - - 38907 1399.00 1.415 1.25 -0.178873958169795 Down 0.0982366926429798 CG13675 CG13675, isoform D - - GO:0030247//polysaccharide binding GO:0006022 19835141 675.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 37643 2294.87 100.625 83.405 -0.270783004528829 Down 0.487782327301545 CG42678 CG42678, isoform S K11449|1|2e-52|207|cfa:474695|jumonji domain-containing protein 1 [EC:1.14.11.-];K00939|2|2e-07|58.5|bmy:Bm1_13790|adenylate kinase [EC:2.7.4.3] - - - 12798223 799.00 0.01 0.06 2.58496250072116 Up 0.0905758816536785 CG43230 CG43230 - - - - 32765 1755.50 28.11 26.715 -0.073433436557568 Down 0.171509708096685 CG15814 CG15814, isoform D - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 39793 774.00 256.4 144.215 -0.830175032883126 Down 0.713413023378682 CG4962 CG4962 - - - - 32950 2301.00 4.525 0.06 -6.23681148124941 Down 0.76911900673623 CG14204 CG14204, isoform B K00680|1|0.0|659|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 48535 2140.86 39.32 36.765 -0.0969303367525848 Down 0.232961299696209 Hrb87F heterogeneous nuclear ribonucleoprotein at 87F, isoform E K12741|1|3e-112|405|dme:Dmel_CG12749|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex;GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0005700//polytene chromosome;GO:0030529//ribonucleoprotein complex GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003677//DNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 34510 598.00 0.23 0.155 -0.569365645670138 Down 0.0842359001452912 CG14069 CG14069, isoform B - - - - 39446 2273.01 28.745 31.645 0.138666536989112 Up 0.291176859067494 CG10984 CG10984, isoform D K13100|1|5e-06|53.5|dvi:Dvir_GJ19836|pre-mRNA-splicing factor CWC22 - - - 32193 935.49 0.18 0.35 0.959358015502654 Up 0.136144498745212 CG15927 CG15927, isoform B - - - - 43034 1831.00 9.935 12.975 0.385142665995573 Up 0.447563069607714 CG10420 CG10420 K14001|1|0.0|762|dme:Dmel_CG10420|nucleotide exchange factor SIL1 - - - 34454 758.00 0.78 1.395 0.838719092966939 Up 0.262250693435477 CG6138 CG6138 K10649|1|2e-69|232|dsi:Dsim_GD23717|tripartite motif-containing protein 9/67 GO:0044464//cell part - - 35288 2185.45 1.88 1.195 -0.653722043696889 Down 0.26274600449082 lok loki, isoform D K06641|1|0.0|903|dme:Dmel_CG10895|serine/threonine-protein kinase Chk2 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0033554//cellular response to stress;GO:0031570;GO:0008629;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0031570;GO:0008629;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0031570;GO:0008629;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006464//cellular protein modification process 3355016 512.91 352.965 368.04 0.0603374394517786 Up 0.183066966054682 CG40127 CG40127, isoform B - GO:0031224//intrinsic to membrane GO:0004519//endonuclease activity GO:0006351//transcription, DNA-dependent 43041 8551.46 10.98 10.11 -0.119095057102184 Down 0.192676000528332 Nup358 nucleoporin 358kD, isoform B K12172|1|0.0|4714|dme:Dmel_CG11856|E3 SUMO-protein ligase RanBP2 GO:0044464//cell part GO:0046914//transition metal ion binding GO:0006810//transport 37334 1917.00 1.7 2.12 0.318529518425497 Up 0.181779157310791 CG13436 CG13436 - - - - 326186 1875.35 41.965 47.375 0.174939362473989 Up 0.351076476026945 scramb1 scramblase 1, isoform C K08267|1|7e-06|52.4|spu:591989|rapamycin-insensitive companion of mTOR - - GO:0007009//plasma membrane organization;GO:0007267//cell-cell signaling;GO:0007009//plasma membrane organization;GO:0007267//cell-cell signaling;GO:0007009//plasma membrane organization;GO:0007267//cell-cell signaling 45845 569.00 82.305 108.115 0.393514716494213 Up 0.582221635186897 Dsk drosulfakinin - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0006937//regulation of muscle contraction 43624 1882.00 1.145 0.705 -0.69965243569815 Down 0.212224276845859 PH4alphaMP prolyl-4-hydroxylase-alpha MP K00472|1|0.0|1085|dme:Dmel_CG9726|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 5740468 518.00 5.46 4.1 -0.413277041414407 Down 0.337868181217805 CG34213 CG34213 - - - - 12798254 503.00 0.82 1.005 0.293499686560845 Up 0.114449874521199 CG43121 CG43121 - - - - 42443 4319.00 6.07 5.29 -0.198428794141656 Down 0.218234050984018 CG15923 CG15923, isoform C - - - - 34626 4340.00 8.285 9.925 0.260565404808868 Up 0.320829480914014 rab3-GAP Rab3 GTPase activating protein, isoform B - GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle - GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport 36736 4045.81 21.94 25.165 0.197855072093709 Up 0.353850217936864 CG30089 CG30089, isoform B - - - - 43436 3211.00 28.82 28.85 0.00150098335809748 Up 0.0427618544445912 alpha-Man-Ib alpha mannosidase Ib K01230|1|0.0|1399|dme:Dmel_CG11874|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] GO:0044464//cell part GO:0046872//metal ion binding;GO:0015924 - 37176 8518.76 13.42 15.91 0.245549164130864 Up 0.3632941487254 CG15099 CG15099, isoform B - - - - 40510 2635.33 22.95 9.55 -1.26492151537806 Down 0.69601109496764 slif slimfast, isoform C K13865|1|1e-141|503|mdo:100013702|solute carrier family 7 (cationic amino acid transporter), member 3 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity GO:0044238//primary metabolic process;GO:0015837//amine transport;GO:0044238//primary metabolic process;GO:0015837//amine transport;GO:0044238//primary metabolic process;GO:0015837//amine transport 3772677 1251.00 8.435 9.055 0.102326572662602 Up 0.158631620657773 snapin snapin ortholog K00571|1|2e-31|136|hsa:29104|site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] - GO:0005488//binding;GO:0016741 GO:0016079//synaptic vesicle exocytosis;GO:0006730//one-carbon metabolic process 42964 2691.59 21.94 19.885 -0.141882963597982 Down 0.270406815480122 nct nicastrin, isoform E K06171|1|0.0|1382|dme:Dmel_CG7012|nicastrin GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006996//organelle organization;GO:0042478//regulation of eye photoreceptor cell development;GO:0042051//compound eye photoreceptor development;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051604//protein maturation;GO:0033619//membrane protein proteolysis;GO:0007166//cell surface receptor signaling pathway;GO:0006996//organelle organization;GO:0042478//regulation of eye photoreceptor cell development;GO:0042051//compound eye photoreceptor development;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051604//protein maturation;GO:0033619//membrane protein proteolysis;GO:0007166//cell surface receptor signaling pathway;GO:0006996//organelle organization;GO:0042478//regulation of eye photoreceptor cell development;GO:0042051//compound eye photoreceptor development;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0051604//protein maturation;GO:0033619//membrane protein proteolysis;GO:0007166//cell surface receptor signaling pathway 37676 2988.00 0.04 0.1 1.32192809488736 Up 0.0864152687887994 CG9899 CG9899 K09667|1|3e-06|54.7|cel:K04G7.3|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - - - 43489 1536.00 0.43 0.235 -0.87167590302446 Down 0.142154272883371 ppk19 pickpocket 19 K04829|1|1e-11|71.6|spu:575477|amiloride-sensitive cation channel 2, neuronal;K04832|2|2e-10|67.4|hsa:51802|amiloride-sensitive cation channel 5, intestinal GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 41657 4955.26 18.515 22.105 0.255678184782436 Up 0.403744551578391 CG14372 CG14372, isoform D K06491|1|6e-22|107|dre:767777|neural cell adhesion molecule - - - 42202 615.00 0.34 0.01 -5.08746284125034 Down 0.291771232333906 CG7126 CG7126 - - - - 53567 7066.41 55.73 53.805 -0.0507139073994248 Down 0.148659358076872 larp La related protein, isoform H K11090|1|3e-06|55.8|nvi:100121050|lupus La protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0048308//organelle inheritance;GO:0000070//mitotic sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0048102//autophagic cell death;GO:0007140//male meiosis;GO:0048308//organelle inheritance;GO:0000070//mitotic sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0048102//autophagic cell death;GO:0007140//male meiosis;GO:0048308//organelle inheritance;GO:0000070//mitotic sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0048102//autophagic cell death;GO:0007140//male meiosis;GO:0048308//organelle inheritance;GO:0000070//mitotic sister chromatid segregation;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0048102//autophagic cell death;GO:0007140//male meiosis 42804 1769.85 18.83 16.895 -0.156436649450427 Down 0.283284902919033 RanBP3 Ran binding protein 3, isoform B - - - - 43181 972.00 0.92 0.845 -0.122682519774829 Down 0.0700369832254656 CG34129 CG34129 K08663|1|2e-13|76.3|mcc:705477|granzyme K [EC:3.4.21.-];K01352|2|3e-13|75.9|xtr:100135014|granzyme A [EC:3.4.21.78];K01312|3|4e-13|75.5|dpo:Dpse_GA11574|trypsin [EC:3.4.21.4];K09622|5|8e-13|74.3|cfa:484348|kallikrein 14 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462897 945.00 0.25 0.555 1.15055967657538 Up 0.195284638753137 CG43931 CG43931 - - - - 41340 663.04 271.13 301.86 0.15489484208731 Up 0.353718134988773 SdhC succinate dehydrogenase C, isoform B K00236|1|2e-78|291|dse:Dsec_GM26120|succinate dehydrogenase (ubiquinone) cytochrome b subunit [EC:1.3.5.1] GO:0005746//mitochondrial respiratory chain;GO:0044459//plasma membrane part GO:0000104//succinate dehydrogenase activity GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain;GO:0009060//aerobic respiration;GO:0006950//response to stress 33347 2357.00 18.44 20.325 0.140416696533052 Up 0.265486725663717 CG17660 CG17660 - GO:0031224//intrinsic to membrane - - 38372 4548.19 38.965 41.365 0.0862317658110313 Up 0.21559239202219 prominin-like prominin-like, isoform G K06532|1|0.0|1626|dme:Dmel_CG7740|prominin GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 41767 484.00 1986.955 1544.51 -0.363409987414375 Down 0.5841038171972 Cys Cystatin-like K01373|1|6e-12|70.1|dgr:Dgri_GH22731|cathepsin F [EC:3.4.22.41] - - - 7354433 3150.00 15.44 16.89 0.129496575533305 Up 0.238706907938185 CG42368 CG42368 K06774|1|2e-32|141|mmu:235106|neurotrimin - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33671 1685.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 CG3251 CG3251 K13718|1|0.0|710|dsi:Dsim_GD22696|OTU domain-containing protein 4 - - GO:0006996//organelle organization;GO:0032875//regulation of DNA endoreduplication;GO:0007275//multicellular organismal development;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation 14462842 530.00 0.24 0.585 1.28540221886225 Up 0.209483555672963 40481 865.85 0.48 0.47 -0.0303736490435187 Down 0.0416391493858143 CG14456 CG14456, isoform B - - - - 8674046 814.00 8.94 9.915 0.14933794104553 Up 0.219191652357681 CG42498 CG42498 K03861|1|1e-75|282|dme:Dmel_CG14550|phosphatidylinositol glycan, class P - - - 35156 1738.46 43.67 43.155 -0.017114809319812 Down 0.0832452780346057 CG10639 CG10639, isoform C K00109|1|0.0|875|dme:Dmel_CG10639|2-hydroxyglutarate dehydrogenase [EC:1.1.99.2] GO:0044444//cytoplasmic part GO:0003824//catalytic activity - 34479 964.00 35.145 35.54 0.0161242264443865 Up 0.0805045568617092 CG6750 CG6750 - - - - 39317 1727.65 15.555 15.455 -0.00930474067615842 Down 0.0547483819838859 CG11652 CG11652, isoform C - - - - 37731 1071.88 7.415 9.74 0.393475079627711 Up 0.411306300356624 Rrp4 Rrp4, isoform B K03679|1|4e-161|567|dme:Dmel_CG3931|exosome complex component RRP4 GO:0000178//exosome (RNase complex);GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0006396//RNA processing 32008 1327.09 3.2 4.85 0.599912842187128 Up 0.393508123101308 Ant2 adenine nucleotide translocase 2, isoform C K05863|1|7e-161|566|dme:Dmel_CG1683|solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part GO:0015300;GO:0015300 GO:0016192//vesicle-mediated transport;GO:0015868//purine ribonucleotide transport;GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0010259//multicellular organismal aging;GO:0042391//regulation of membrane potential;GO:0009605//response to external stimulus;GO:0016192//vesicle-mediated transport;GO:0015868//purine ribonucleotide transport;GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0010259//multicellular organismal aging;GO:0042391//regulation of membrane potential;GO:0009605//response to external stimulus 41366 4806.00 2.14 1.795 -0.253626952578095 Down 0.15037643640206 Blm bloom syndrome helicase ortholog K10901|1|0.0|2732|dme:Dmel_CG6920|bloom syndrome protein [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0000217//DNA secondary structure binding;GO:0003690//double-stranded DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032559 GO:0000724//double-strand break repair via homologous recombination;GO:0032392//DNA geometric change 42829 1029.00 0.46 0.655 0.509861045480438 Up 0.133139611676133 CG13599 CG13599 - GO:0043231//intracellular membrane-bounded organelle - GO:0007346//regulation of mitotic cell cycle 39124 870.00 3.58 1.375 -1.38052796885223 Down 0.501485933166028 CG18179 CG18179 K01310|1|1e-141|502|dme:Dmel_CG18179|chymotrypsin [EC:3.4.21.1];K01362|2|2e-47|189|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39158 5411.71 8.395 9.835 0.2283947273415 Up 0.294941223088099 Gap1 Ras GTPase activating protein 1, isoform C K12380|1|0.0|2007|dme:Dmel_CG6721|Ras GTPase-activating protein 3 GO:0016020//membrane;GO:0016020//membrane GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0007424//open tracheal system development;GO:0007143//female meiosis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007059//chromosome segregation;GO:0000578//embryonic axis specification;GO:0000087//M phase of mitotic cell cycle;GO:0007472//wing disc morphogenesis;GO:0045676//regulation of R7 cell differentiation;GO:0046578//regulation of Ras protein signal transduction;GO:0007424//open tracheal system development;GO:0007143//female meiosis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007059//chromosome segregation;GO:0000578//embryonic axis specification;GO:0000087//M phase of mitotic cell cycle;GO:0007472//wing disc morphogenesis 32871 1850.00 38.77 40.82 0.0743354472815388 Up 0.18187821952186 CG7053 Autophagy-specific gene 101 - GO:0005737//cytoplasm - GO:0044248//cellular catabolic process 5740318 7935.74 38.8 42.92 0.145593423682032 Up 0.317065116893409 CG43729 CG43729, isoform V K04705|1|3e-08|62.0|oaa:100078098|signal transducing adaptor molecule - GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding GO:0023033;GO:0023033;GO:0023033;GO:0023033 31396 942.00 0.415 1.105 1.41286312804451 Up 0.3060692114648 CG3062 CG3062 - - - - 34053 1041.00 1134.945 1440.35 0.343797038614929 Up 0.57112666754722 CG7214 CG7214 - - - - 19835617 401.00 0.01 0.125 3.64385618977472 Up 0.151697265882974 31883 3468.00 1.95 2.965 0.604557980796393 Up 0.314819706775855 lz lozenge, isoform B K09280|1|0.0|684|dse:Dsec_GM22478|runt-related transcription factor, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0032559;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0032559;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0035163//embryonic hemocyte differentiation;GO:0035168//larval lymph gland hemocyte differentiation;GO:0009611//response to wounding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0006915//apoptotic process;GO:0001709//cell fate determination;GO:0042051//compound eye photoreceptor development;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0035163//embryonic hemocyte differentiation;GO:0035168//larval lymph gland hemocyte differentiation;GO:0009611//response to wounding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0006915//apoptotic process;GO:0001709//cell fate determination;GO:0042051//compound eye photoreceptor development 42970 1206.81 42.495 51.39 0.2741945497059 Up 0.467507594769515 Ela Elastin-like, isoform C - - - - 44543 7815.24 28.93 31.355 0.11612919631573 Up 0.25799101835953 enc encore, isoform H K02360|1|0.0|2043|dme:Dmel_CG10847|a component of the cytoplasm (encore) GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part - GO:0007309//oocyte axis specification;GO:0051276//chromosome organization;GO:0044087;GO:0000087//M phase of mitotic cell cycle;GO:0008283//cell proliferation;GO:0007309//oocyte axis specification;GO:0051276//chromosome organization;GO:0044087;GO:0000087//M phase of mitotic cell cycle;GO:0008283//cell proliferation;GO:0007309//oocyte axis specification;GO:0051276//chromosome organization;GO:0044087;GO:0000087//M phase of mitotic cell cycle;GO:0008283//cell proliferation;GO:0007309//oocyte axis specification;GO:0051276//chromosome organization;GO:0044087;GO:0000087//M phase of mitotic cell cycle;GO:0008283//cell proliferation 36938 440.00 0.495 0.01 -5.62935662007961 Down 0.356888125742967 CG17290 CG17290, isoform C - - - - 5740480 353.00 5.78 3.215 -0.846250755172731 Down 0.490556069211465 CG34247 CG34247 - - - - 41842 5525.72 12.46 14.28 0.196691911005098 Up 0.305805045568617 CG42404 CG42404, isoform F - - - - 35892 1036.00 15.38 12.73 -0.272823084060468 Down 0.382115968828424 CG8235 CG8235 K01874|1|1e-49|196|cel:F58B3.5|methionyl-tRNA synthetase [EC:6.1.1.10];K01866|4|1e-42|173|mdo:100025987|tyrosyl-tRNA synthetase [EC:6.1.1.1] - GO:0003723//RNA binding - 39669 1495.00 9.69 8.645 -0.1646307017728 Down 0.231310262845067 CG7275 CG7275 K11806|1|0.0|896|dme:Dmel_CG7275|WD repeat and SOF domain-containing protein 1 - GO:0008415 - 19835509 328.00 0.15 0.01 -3.90689059560852 Down 0.171410645885616 37646 2461.39 115.35 126.85 0.137105515380956 Up 0.329348831065909 CG3800 CG3800, isoform B K09250|1|4e-83|309|dme:Dmel_CG3800|cellular nucleic acid-binding protein - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 246672 403.00 2.09 1.18 -0.824716082719041 Down 0.31812178047814 Obp22a Odorant-binding protein 22a, isoform C - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 49762 551.00 25.71 21.455 -0.26101570908527 Down 0.416754721965394 l(3)87Df lethal (3) 87Df - - - - 5740234 520.00 0.945 1.055 0.158856764486112 Up 0.0833443402456743 CG34284 CG34284 - - - - 35825 2036.00 0.52 0.495 -0.0710830980614826 Down 0.049432043323207 Mal-A2 maltase A2 K01187|1|0.0|1167|dme:Dmel_CG8694|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding;GO:0015926//glucosidase activity GO:0019318//hexose metabolic process 33890 3704.00 0.305 0.16 -0.930737337562886 Down 0.122341830669661 slam slow as molasses, isoform C - - - GO:0007276//gamete generation;GO:0007275//multicellular organismal development;GO:0033036;GO:0009987//cellular process 41264 660.00 0.405 0.445 0.135883428081773 Up 0.0587769119006736 CG18545 CG18545 - - - - 37626 1569.00 0.055 0.06 0.125530882083859 Up 0.0444459120327566 CG3649 CG3649 K08193|1|3e-63|242|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other;K12301|3|3e-52|206|cin:100187364|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 - - GO:0006810//transport 3772073 609.00 0.2 0.08 -1.32192809488736 Down 0.12012944128913 CheB74a chemosensory protein B 74a - GO:0044421//extracellular region part - GO:0009593//detection of chemical stimulus 318221 1063.00 3.83 6.11 0.673827987893773 Up 0.45307753269053 CG32808 CG32808 K08668|1|7e-27|120|mmu:23993|kallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117];K09641|2|1e-23|110|bta:521615|transmembrane protease, serine 11D [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31680 3420.00 3.335 3.24 -0.0416929482999601 Down 0.0622440892880729 Hira hira K11293|1|0.0|1878|dme:Dmel_CG12153|protein HIRA/HIR1 - - - 39012 800.00 1.57 1.66 0.080418682455298 Up 0.0667679302602034 CG13309 CG13309 - - GO:0030247//polysaccharide binding GO:0006022 37927 2183.23 21.31 16.69 -0.352546638420105 Down 0.476984546295073 Start1 Start1, isoform D - - GO:0015248//sterol transporter activity;GO:0032934//sterol binding;GO:0015248//sterol transporter activity;GO:0032934//sterol binding GO:0008202//steroid metabolic process;GO:0008202//steroid metabolic process 12797925 147.00 0.75 0.44 -0.769387071858584 Down 0.180920618148197 32290 4821.78 8.88 11.3 0.347691190952444 Up 0.406155065381059 Syt12 synaptotagmin 12, isoform B K01104|1|6e-31|137|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|2|1e-16|89.7|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10] - GO:0005543//phospholipid binding GO:0001505//regulation of neurotransmitter levels 33788 3253.00 1.99 3.49 0.810458605666003 Up 0.399121648395192 GluRIIA glutamate receptor IIA K05313|1|0.0|1699|dme:Dmel_CG6992|glutamate receptor, ionotropic, invertebrate;K05201|4|2e-114|414|rno:29559|glutamate receptor, ionotropic, kainate 1 GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0045202//synapse;GO:0044430//cytoskeletal part GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0050804//regulation of synaptic transmission 43373 2545.00 21.54 18.75 -0.200127654273602 Down 0.343580768722758 Gfat2 Glutamine:fructose-6-phosphate aminotransferase 2 K00820|1|0.0|1329|dme:Dmel_CG1345|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] GO:0044424//intracellular part GO:0030246//carbohydrate binding;GO:0008483//transaminase activity GO:0005975//carbohydrate metabolic process 14462786 422.00 0.105 0.115 0.131244533278252 Up 0.0444459120327566 12798406 278.00 68.085 44.865 -0.601746577818542 Down 0.649848104609695 CG43114 CG43114, isoform B - - - - 35395 2541.00 4.22 3.595 -0.231251228267887 Down 0.201591599524501 CG8679 CG8679 K10380|1|1e-08|62.4|dan:Dana_GF23392|ankyrin GO:0012505//endomembrane system - - 36921 3118.83 2.085 2.445 0.22978708150757 Up 0.152786950204729 CG8950 CG8950, isoform B - - - - 246434 1648.00 0.09 0.145 0.68805599368526 Up 0.080537577598732 Obp50c Odorant-binding protein 50c - - GO:0005488//binding GO:0051234//establishment of localization 31127 2210.00 7.68 8.515 0.148900218957386 Up 0.207766477347774 a6 a6, isoform C - - - - 47781 3052.00 7.16 7.41 0.0495139550415775 Up 0.0905758816536785 fs(1)K10 female sterile (1) K10 K02524|1|4e-53|210|dme:Dmel_CG3218|DNA binding protein (fs(1)K10, female sterile(1)K10) GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006412//translation;GO:0007316//pole plasm RNA localization 19834861 1101.12 1.85 20.83 3.49306566352433 Up 0.797781006472064 246588 1216.00 0.575 0.57 -0.0126000367796333 Down 0.0382380134724607 CG30393 CG30393 - - - - 2768968 3690.00 0.69 0.72 0.0614005446641433 Up 0.0489697530048871 CG33288 CG33288 K10614|1|4e-07|57.8|xla:444030|E3 ubiquitin-protein ligase HERC3 [EC:6.3.2.19] - - - 33283 3539.52 40.14 34.725 -0.209065922493862 Down 0.392583542464668 Atg4 Autophagy-specific gene 4a, isoform B K08342|1|0.0|819|dme:Dmel_CG4428|autophagy-related protein 4 [EC:3.4.22.-] GO:0044424//intracellular part GO:0004672//protein kinase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0032559 GO:0006464//cellular protein modification process;GO:0006810//transport;GO:0044248//cellular catabolic process 44785 1577.16 11.715 13.58 0.213126525381596 Up 0.31267335886937 tan tantalus, isoform B - GO:0043231//intracellular membrane-bounded organelle - GO:0048513//organ development 35475 3329.97 40.02 44.355 0.14837557693574 Up 0.318914278166689 CG3107 CG3107, isoform D K06972|1|0.0|2068|dme:Dmel_CG3107| GO:0031980;GO:0031980;GO:0031980 GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 36613 651.00 15.02 13.495 -0.15445983604742 Down 0.257726852463347 Cpr51A cuticular protein 51A - - GO:0005198//structural molecule activity - 39264 755.00 37.22 34.14 -0.124614997031413 Down 0.267600052833179 CG14141 CG14141 - - - - 36862 5718.78 17.66 21.31 0.271045250134237 Up 0.412263901730287 gprs gprs, isoform F K10481|1|6e-13|77.4|nvi:100121671|BTB/POZ domain-containing protein 9 - - - 33902 1248.54 26.285 28.985 0.141066750702636 Up 0.287709681680095 CG9531 CG9531, isoform B K00599|1|0.0|652|dme:Dmel_CG9531| [EC:2.1.1.-] - GO:0005488//binding;GO:0008168//methyltransferase activity GO:0006730//one-carbon metabolic process;GO:0008213 41809 3462.79 14.92 13.655 -0.127818221489951 Down 0.229593184519878 CG3837 secreted decoy of InR, isoform B K04527|1|2e-92|340|tca:661524|insulin receptor [EC:2.7.10.1];K05087|2|2e-85|318|tgu:100227374|insulin-like growth factor 1 receptor [EC:2.7.10.1] - - - 37962 3937.00 6.285 6.835 0.121028593185552 Up 0.160084533086779 egg eggless K11421|1|0.0|2318|dme:Dmel_CG12196|histone-lysine N-methyltransferase SETDB [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003690//double-stranded DNA binding GO:0032583;GO:0007444//imaginal disc development;GO:0042078//germ-line stem cell division;GO:0009791//post-embryonic development;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0007292//female gamete generation;GO:0044030//regulation of DNA methylation;GO:0034968//histone lysine methylation 34000 2279.55 2.43 1.215 -1 Down 0.379342226918505 CG4496 CG4496, isoform C K09228|1|6e-25|116|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 42670 2480.43 3.15 4.235 0.42701014094492 Up 0.307290978734645 EF-G2 elongation factor G2, isoform B K02355|1|0.0|1410|dme:Dmel_CG31159|elongation factor EF-G [EC:3.6.5.3] GO:0043231//intracellular membrane-bounded organelle GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0032988;GO:0006412//translation 12797997 531.00 0.31 0.09 -1.78427130894456 Down 0.171773873992868 CG43054 CG43054 - - - - 32602 1439.86 48.06 50.605 0.0744432882073579 Up 0.186336019019945 U2af50 U2 small nuclear riboprotein auxiliary factor 50, isoform D K12837|1|0.0|671|dya:Dyak_GE15975|splicing factor U2AF 65 kDa subunit GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0003727//single-stranded RNA binding;GO:0046983//protein dimerization activity GO:0000278//mitotic cell cycle;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport 59169 1354.00 0.365 0.525 0.524420958786105 Up 0.120030379078061 CG18808 CG18808 - - GO:0003824//catalytic activity GO:0008152//metabolic process 33933 1427.00 0.06 0.125 1.05889368905357 Up 0.0856557918372738 CG13771 CG13771, isoform B - - - - 246444 868.00 9.845 9.455 -0.0583137479517926 Down 0.113162065777308 CG30083 CG30083 K09632|1|5e-32|137|dre:447843|chymotrypsin-like protease [EC:3.4.21.-];K08664|3|3e-30|132|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-];K01316|5|4e-28|125|mmu:19146|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31602 4996.00 12.125 15.805 0.382396287942646 Up 0.466649055606921 CG3198 CG3198 K13212|1|7e-15|82.8|xla:379905|RNA-binding protein Luc7-like 2 - - - 37323 2822.00 14 14.29 0.0295790892634876 Up 0.0854246466781138 Mgat1 UDP-GlcNAc:a-3-D-mannoside-beta-1, 2-N-acetylglucosaminyltransferase I K00726|1|0.0|919|dme:Dmel_CG13431|alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.101] - - - 14462437 786.25 2.045 2.245 0.134614601799398 Up 0.101406683397173 14462674 245.00 0.76 0.22 -1.78849589480629 Down 0.281171575749571 CG44139 CG44139 - - - - 42099 1143.00 2.09 3 0.521459558414998 Up 0.29286091665566 CG14331 CG14331 - - - - 31597 894.00 31.465 31.245 -0.0101226028102487 Down 0.0615836745476159 CG3226 CG3226 K04507|1|9e-127|452|dme:Dmel_CG3226|calcyclin binding protein - - - 39925 571.00 0.355 0.4 0.17218097538268 Up 0.0647866860388324 CG13723 CG13723 - - - - 33761 9954.33 6.995 7.285 0.0586049148997593 Up 0.100184916127328 Ncoa6 Ncoa6, isoform F - - - - 35178 3281.00 0.08 0.12 0.584962500721156 Up 0.0687491744815744 Phlpp PH domain leucine-rich repeat protein phosphatase, isoform B K01090|1|3e-50|200|mdo:100024744|protein phosphatase [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity;GO:0003774//motor activity;GO:0000166//nucleotide binding GO:0006464//cellular protein modification process 2768929 6055.40 11.195 12.24 0.128749029840054 Up 0.213941355171047 CG33298 CG33298, isoform D K01530|1|0.0|2784|dme:Dmel_CG33298|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559 GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport;GO:0009206;GO:0006869//lipid transport 36420 1977.92 30.015 29.185 -0.0404565997446582 Down 0.119237881389513 Aats-asp Aspartyl-tRNA synthetase, isoform C K01876|1|0.0|969|dme:Dmel_CG3821|aspartyl-tRNA synthetase [EC:6.1.1.12] GO:0015630//microtubule cytoskeleton GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 14462461 557.00 0.15 0.085 -0.819427754358179 Down 0.0821225729758288 42150 10440.24 26.385 39.11 0.567819552539828 Up 0.61851142517501 Rim Rab3 interacting molecule, isoform Z K00923|1|8e-16|88.2|nve:NEMVE_v1g90881|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154];K01104|3|6e-12|75.5|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48] - - - 317890 774.00 0.915 1.71 0.902152676601855 Up 0.305474838198389 CG32161 CG32161 - - - - 39436 924.00 22.3 20.53 -0.119310082699065 Down 0.241117421740853 CG10688 CG10688 K01840|1|2e-145|514|dme:Dmel_CG10688|phosphomannomutase [EC:5.4.2.8] GO:0044424//intracellular part GO:0016868//intramolecular transferase activity, phosphotransferases GO:0009226//nucleotide-sugar biosynthetic process;GO:0006013//mannose metabolic process 42309 1247.00 5.705 5.06 -0.173089501594371 Down 0.190364548936732 CG3773 CG3773 - - - - 39804 953.97 0.07 0.285 2.02553509210714 Up 0.171377625148593 CG13040 CG13040, isoform B - - - - 12798054 482.23 3.755 2.12 -0.824748642951073 Down 0.412990357944789 CG43254 CG43254, isoform B - - - - 246591 1029.00 1.145 1.025 -0.159723688591498 Down 0.0861841236296394 CG30398 CG30398 - - - - 32942 711.00 0.115 0.065 -0.823122237915921 Down 0.07657508915599 CG12231 CG12231 - - - GO:0048598//embryonic morphogenesis 19835271 597.00 0.2 0.36 0.84799690655495 Up 0.129375247655528 42782 2058.00 0.04 0.01 -2 Down 0.0694426099590543 CG10183 CG10183 K00680|1|0.0|685|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 37755 3171.69 66.47 45.16 -0.557657867784691 Down 0.63855501254788 Sesn sestrin, isoform D K10141|1|0.0|937|dme:Dmel_CG11299|sestrin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0022402//cell cycle process;GO:0002118//aggressive behavior;GO:0022402//cell cycle process;GO:0002118//aggressive behavior;GO:0022402//cell cycle process;GO:0002118//aggressive behavior 12797998 1180.00 0.165 0.115 -0.52083216330144 Down 0.0744617619865275 CG43231 CG43231 - - - - 41233 708.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 Npc2c Niemann-Pick type C-2c K13443|1|1e-18|92.8|aga:AgaP_AGAP002851|Niemann-Pick C2 protein - - - 31098 1634.00 4.525 5.325 0.234863733142633 Up 0.228668603883239 O-fut2 O-fucosyltransferase 2 K03691|1|0.0|917|dme:Dmel_CG14789|peptide-O-fucosyltransferase [EC:2.4.1.221] - - - 36341 6284.00 0.41 0.625 0.608232280044003 Up 0.139380530973451 ana3 anastral spindle 3 - - - - 32923 1846.00 0.515 0.4 -0.364572432295856 Down 0.101010434552899 CG8028 CG8028, isoform D K08189|1|1e-15|85.1|mcc:713985|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13 - - GO:0006810//transport;GO:0006810//transport 38914 3199.00 16.155 16.04 -0.0103066088104436 Down 0.0563994188350284 MED24 mediator complex subunit 24 - GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 42999 1012.62 47.365 49.615 0.0669549690748451 Up 0.183463214898957 CG11790 CG11790, isoform C K09582|1|6e-06|51.6|dre:554998|protein disulfide-isomerase A4 [EC:5.3.4.1] - - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis 43497 574.80 128.7 116.015 -0.14970070487328 Down 0.3452318055739 Obp99b Odorant-binding protein 99b, isoform B - - GO:0005488//binding GO:0051234//establishment of localization;GO:0007600//sensory perception;GO:0048102//autophagic cell death;GO:0010033//response to organic substance;GO:0007635//chemosensory behavior 37807 1207.81 36.74 37.41 0.0260723394394768 Up 0.101340641923128 CG2970 CG2970, isoform B K03364|1|2e-151|535|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0044464//cell part - - 33683 2963.92 2.845 2.425 -0.230443905232092 Down 0.164872539955092 Ir25a ionotropic receptor 25a, isoform E K05313|1|0.0|1820|dme:Dmel_CG15627|glutamate receptor, ionotropic, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 31995 2805.00 0.14 0.135 -0.0524674198941355 Down 0.0419363360190199 CG2111 CG2111 K11140|1|2e-157|556|der:Dere_GG12022|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0006909//phagocytosis;GO:0019538//protein metabolic process 32571 997.00 0.39 0.305 -0.354664881299362 Down 0.0895192180689473 CG12395 CG12395 - - - - 40412 3438.80 0.62 0.38 -0.70626879694329 Down 0.152786950204729 CG32447 CG32447, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004872//receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway 117477 1446.00 0.435 0.36 -0.273018494406416 Down 0.080768722757892 Gr64f gustatory receptor 64f K08471|1|0.0|884|dme:Dmel_CG32255|gustatory receptor - - - 31573 1282.00 13.65 11.21 -0.284114673001788 Down 0.379144102496368 CG3823 CG3823 K10693|1|3e-119|428|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] - - - 34754 800.23 628.865 572.83 -0.134643292672394 Down 0.32403249240523 RpL24 ribosomal protein L24, isoform C K02896|1|7e-49|193|dsi:Dsim_GD22063|large subunit ribosomal protein L24e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 34470 538.00 1.09 1 -0.124328135002202 Down 0.0725465592392022 CG7294 CG7294 - - - - 3885592 460.00 0.275 0.925 1.75002174699165 Up 0.307489103156782 CG34029 CG34029 - - - - 31960 996.00 96.28 78.72 -0.290505921135257 Down 0.507231541408004 Gip GIP-like K01816|1|7e-150|529|dme:Dmel_CG2227|hydroxypyruvate isomerase [EC:5.3.1.22] - - - 3772551 173.00 0.465 0.21 -1.14684138832927 Down 0.176033549068815 35107 6211.11 20.3 22.145 0.125501269812778 Up 0.254854048342359 Pde11 phosphodiesterase 11, isoform G K13298|1|0.0|1859|dme:Dmel_CG34341|dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35] - GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity GO:0023060;GO:0023060;GO:0023060;GO:0023060 32152 5127.00 0.14 0.215 0.618909832644494 Up 0.0900145291242901 wisp wispy, isoform C K00970|1|0.0|1700|dme:Dmel_CG15737|poly(A) polymerase [EC:2.7.7.19];K13291|3|4e-24|114|hmg:100208804|terminal uridylyltransferase [EC:2.7.7.52] - GO:0070566//adenylyltransferase activity GO:0000278//mitotic cell cycle;GO:0007097//nuclear migration;GO:0001775//cell activation;GO:0000741//karyogamy;GO:0031124//mRNA 3'-end processing;GO:0000226//microtubule cytoskeleton organization;GO:0007143//female meiosis;GO:0003006//developmental process involved in reproduction;GO:0006403//RNA localization 37005 3145.43 69.445 60.595 -0.196672070190931 Down 0.402126535464272 eIF3-S8 eIF3-S8, isoform B K03252|1|0.0|1466|dse:Dsec_GM21808|translation initiation factor eIF-3 subunit 8 - - - 33570 1402.00 53.875 16.4 -1.71592014935838 Down 0.75891559899617 CG15414 CG15414 - - - - 14462439 601.00 0.27 0.155 -0.800691191776593 Down 0.110652489763572 32267 2256.00 4.965 4.69 -0.0822057950129974 Down 0.104807819310527 CG4332 CG4332 - - - - 38893 3722.00 15.615 17.6 0.172642859504086 Up 0.293620393607185 CG7565 CG7565 - - - - 43816 4989.00 32.09 33.31 0.0538315643925436 Up 0.141163650772685 MED26 mediator complex subunit 26, isoform B - - - - 35622 1062.00 60.115 46.17 -0.380769287259835 Down 0.560031699907542 Tsp42El tetraspanin 42El K06497|1|2e-09|63.2|dan:Dana_GF13154|CD63 antigen GO:0016020//membrane - - 38916 1591.92 51.755 41.475 -0.319456265522608 Down 0.514661207238146 Ubc12 ubiquitin conjugating enzyme 12, isoform C K10579|1|7e-105|380|dse:Dsec_GM24960|ubiquitin-conjugating enzyme E2 M [EC:6.3.2.19] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0060255;GO:0006464//cellular protein modification process 31702 3620.38 19.39 24.29 0.325049686529072 Up 0.473682472592788 dpr14 dpr14, isoform B K06772|1|7e-11|68.9|tgu:100229373|limbic system-associated membrane protein - - - 32677 1707.00 9.91 9.45 -0.0685707280780533 Down 0.125148593316603 CG9104 CG9104 - - - GO:0015804//neutral amino acid transport;GO:0048812//neuron projection morphogenesis 32738 1260.00 6.545 7.49 0.19457252651351 Up 0.2342491084401 CG8326 CG8326 - - - - 39055 2576.48 21.305 15.54 -0.455205547770509 Down 0.536884163254524 Slc45-1 Slc45 ortholog 1, isoform D - - - GO:0006810//transport 39310 1628.00 17.815 19.36 0.119986469141295 Up 0.232532030114912 CG7339 CG7339, isoform B K03022|1|5e-104|377|dya:Dyak_GE21834|DNA-directed RNA polymerase III subunit C25 [EC:2.7.7.6] GO:0044451//nucleoplasm part GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 40960 857.76 8.835 9.53 0.109246079358325 Up 0.17250033020737 CG9667 CG9667, isoform B K12870|1|4e-140|496|dme:Dmel_CG9667|pre-mRNA-splicing factor ISY1 GO:0005681//spliceosomal complex - GO:0000377 43530 1229.00 4.565 3.77 -0.276050336715558 Down 0.240324924052305 CG7824 CG7824, isoform C - - - - 8674011 1976.40 0.365 0.955 1.38760426915573 Up 0.282657508915599 CG42570 CG42570, isoform B - - - - 38741 2525.26 12.305 13.715 0.156509964390117 Up 0.25822216351869 CG8398 CG8398, isoform E K10478|1|9e-09|62.4|bta:100125777|BTB/POZ domain-containing protein 3/6 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 41930 984.49 286.02 538.07 0.911677840580551 Up 0.727314753665302 glob1 globin 1, isoform F - - GO:0005506//iron ion binding;GO:0022892 GO:0015669//gas transport 49992 520.78 11.475 15.53 0.436563676086131 Up 0.494386474706115 CG15219 CG15219, isoform C - - - - 39000 651.00 1.96 2.32 0.243271151012364 Up 0.153975696737551 Cp19 chorion protein 19 - GO:0030312//external encapsulating structure - GO:0032501//multicellular organismal process;GO:0003006//developmental process involved in reproduction 41962 3580.57 21.62 18.64 -0.21396466308037 Down 0.355864482895258 CG6006 CG6006, isoform F K08202|1|7e-66|252|dpo:Dpse_GA19517|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - - 37473 6481.79 1.035 2.115 1.03102689562062 Up 0.360619469026549 CG30263 CG30263, isoform C - - - - 10178943 863.00 0.23 0.405 0.816288046827612 Up 0.136111478008189 CG42691 CG42691, isoform B - - - - 50122 332.00 0.53 0.45 -0.236067358233524 Down 0.0784572711662924 CG15461 CG15461 - - - - 19836055 922.00 0.255 0.67 1.39366384848628 Up 0.236923788138951 31840 2088.01 24.545 22.805 -0.106078996508294 Down 0.229758288204993 Bx42 Bx42, isoform B K06063|1|0.0|905|dme:Dmel_CG8264|SNW domain-containing protein 1 GO:0000785//chromatin;GO:0005681//spliceosomal complex GO:0005488//binding GO:0009792//embryo development ending in birth or egg hatching;GO:0007444//imaginal disc development;GO:0000377 5740558 546.00 0.3 0.585 0.963474123974886 Up 0.178146876238278 CG34230 CG34230 - - - - 34816 2149.83 10.715 8.285 -0.371058247455096 Down 0.412957337207766 nimC1 nimrod C1, isoform C K06252|1|5e-34|146|oaa:100076692|tenascin - - - 37250 1436.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 Ir56b ionotropic receptor 56b - - - - 319033 854.86 7.735 6.835 -0.178459953842976 Down 0.225861841236296 Rrp40 Rrp40, isoform B K03681|1|3e-128|457|dme:Dmel_CG31938|exosome complex component RRP40 GO:0000178//exosome (RNase complex) GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0042254//ribosome biogenesis 40414 2724.47 21.345 26.855 0.331292558907895 Up 0.483687755910712 CG11247 CG11247, isoform D K09228|1|3e-67|256|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 31742 757.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 CG15336 CG15336 K09228|1|7e-23|106|dpo:Dpse_GA11270|KRAB domain-containing zinc finger protein;K09230|3|2e-18|91.7|mcc:700600|SCAN domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 40102 4123.10 18.87 19.105 0.0178558347570659 Up 0.0722823933430194 Gbs-76A glycogen binding subunit 76A, isoform D K07189|1|0.0|1166|dme:Dmel_CG9619|protein phosphatase 1, regulatory (inhibitor) subunit 3 - - - 32949 1571.00 4 3.075 -0.379413589548122 Down 0.278827103420948 CG14218 CG14218, isoform C - - - - 32115 7867.69 18.28 14.735 -0.31101900993407 Down 0.433793422269185 Ptp10D protein tyrosine phosphatase 10D, isoform I K01104|1|0.0|2995|dme:Dmel_CG1817|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043005//neuron projection;GO:0016020//membrane;GO:0043005//neuron projection;GO:0016020//membrane;GO:0043005//neuron projection;GO:0016020//membrane;GO:0043005//neuron projection;GO:0016020//membrane GO:0004871//signal transducer activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004871//signal transducer activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004871//signal transducer activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004871//signal transducer activity;GO:0004725//protein tyrosine phosphatase activity GO:0007411//axon guidance;GO:0006796//phosphate-containing compound metabolic process;GO:0060541//respiratory system development;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0006796//phosphate-containing compound metabolic process;GO:0060541//respiratory system development;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0006796//phosphate-containing compound metabolic process;GO:0060541//respiratory system development;GO:0006464//cellular protein modification process;GO:0007411//axon guidance;GO:0006796//phosphate-containing compound metabolic process;GO:0060541//respiratory system development;GO:0006464//cellular protein modification process 34762 1335.00 12.76 16.795 0.396403466469629 Up 0.481838594637432 CG9267 CG9267 K10703|1|3e-29|129|aga:AgaP_AGAP003815|3-hydroxy acyl-CoA dehydratase [EC:4.2.1.-] - - - 36282 2703.77 15.875 15.145 -0.0679150137515182 Down 0.14677717606657 CG8298 CG8298, isoform C K00864|1|0.0|1179|dme:Dmel_CG8298|glycerol kinase [EC:2.7.1.30] - GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process 34287 2124.00 84.74 95.455 0.17177764028705 Up 0.370855897503632 CG4364 CG4364 - GO:0030684//preribosome;GO:0031981//nuclear lumen - GO:0000470//maturation of LSU-rRNA 42865 1993.00 29.845 29.3 -0.026588589140193 Down 0.0984678378021397 Kal1 kallmann syndrome 1 ortholog - - GO:0004857//enzyme inhibitor activity - 34186 628.00 22.815 26.92 0.238695756164665 Up 0.400112270505878 mRpL51 mitochondrial ribosomal protein L51 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 33793 2719.06 8.005 9.685 0.274850646086996 Up 0.328787478536521 CG14010 CG14010, isoform D K06774|1|3e-32|139|mdo:100017555|neurotrimin - - - 14462529 764.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 35956 3027.60 16.51 11.75 -0.490679363460896 Down 0.524270241711795 Myd88 Myd88, isoform C K04729|1|0.0|941|dme:Dmel_CG2078|myeloid differentiation primary response gene 88 GO:0044425//membrane part GO:0004872//receptor activity;GO:0005102//receptor binding GO:0003002//regionalization;GO:0023060;GO:0002815;GO:0002225;GO:0007166//cell surface receptor signaling pathway;GO:0050832//defense response to fungus 34438 2962.76 27.81 20.07 -0.47056312798407 Down 0.563267732135781 RluA-1 RluA-1, isoform D K01718|1|8e-169|594|dme:Dmel_CG6187|pseudouridylate synthase [EC:4.2.1.70];K06043|1|8e-169|594|dme:Dmel_CG6187|tRNA-pseudouridine synthase I [EC:5.4.99.12] - GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding GO:0006771//riboflavin metabolic process;GO:0009451//RNA modification;GO:0006771//riboflavin metabolic process;GO:0009451//RNA modification;GO:0006771//riboflavin metabolic process;GO:0009451//RNA modification 117327 1212.00 0.165 0.11 -0.584962500721156 Down 0.0797781006472064 Gr98b gustatory receptor 98b K08471|1|0.0|739|dme:Dmel_CG31059|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 19835156 334.00 1.62 1.795 0.147990030938426 Up 0.0977744023246599 39658 743.00 0.695 1.185 0.769802176174752 Up 0.231310262845067 CG6888 CG6888 K03386|1|2e-71|268|dwi:Dwil_GK25196|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] - GO:0003824//catalytic activity GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis 8673963 329.00 3.305 3.515 0.0888744175648435 Up 0.0942411834632149 Sfp93F seminal fluid protein 93F - - - - 19835596 1096.82 8.83 6.95 -0.345400460037596 Down 0.372110685510501 37863 2959.00 0.03 0.045 0.584962500721156 Up 0.047450799101836 CG43775 CG43775 - - - - 41581 1173.00 0.105 0.15 0.514573172829758 Up 0.0682868841632545 CG10909 CG10909 - - - - 2768950 436.00 0.29 0.11 -1.39854937649027 Down 0.148857482499009 CG33259 CG33259 - - GO:0004866//endopeptidase inhibitor activity GO:0010259//multicellular organismal aging;GO:0030162//regulation of proteolysis 47873 4144.00 0.06 0.29 2.27301849440642 Up 0.180821555937129 bgcn benign gonial cell neoplasm, isoform B K13185|1|8e-25|116|tgu:100232271|ATP-dependent RNA helicase DHX30 [EC:3.6.4.13];K13184|5|7e-22|107|phu:Phum_PHUM607970|ATP-dependent RNA helicase A [EC:3.6.4.13] - GO:0030371//translation repressor activity;GO:0017111//nucleoside-triphosphatase activity;GO:0000166//nucleotide binding GO:0006996//organelle organization;GO:0007126//meiosis;GO:0048136;GO:0019827//stem cell maintenance 318626 954.58 119.24 21.78 -2.45279242127426 Down 0.799960375115573 CG31205 CG31205, isoform C K01343|1|4e-12|72.0|oaa:100078960|tissue plasminogen activator [EC:3.4.21.68];K03992|2|4e-12|72.0|mmu:17174|mannan-binding lectin serine protease 1 [EC:3.4.21.-];K08664|3|9e-12|70.9|mmu:76560|protease, serine, 8 (prostasin) [EC:3.4.21.-];K09751|5|3e-11|68.9|cfa:482175|transmembrane protease, serine 11B [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38116 5327.11 1.575 2 0.344648171387446 Up 0.183859463743231 bab1 bric a brac 1, isoform E K09237|1|2e-36|155|aga:AgaP_AGAP003537|Cys2His2 zinc finger developmental/cell cycle regulator, other;K02174|3|1e-35|153|dme:Dmel_CG11491|broad GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0050896//response to stimulus;GO:0010468//regulation of gene expression;GO:0007478//leg disc morphogenesis;GO:0048086//negative regulation of developmental pigmentation;GO:0008406//gonad development 5740221 420.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 CG41497 CG41497 K10408|1|2e-21|100|tca:655704|dynein heavy chain, axonemal GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 36573 12808.00 16.835 15.615 -0.108531151807073 Down 0.209318451987848 CG30069 CG30069 K12567|1|7e-57|224|mmu:22138|titin [EC:2.7.11.1] - - - 36492 2256.38 15.47 15.07 -0.0377937798512116 Down 0.101769911504425 cbs centrosomin's beautiful sister, isoform C K11499|1|2e-15|84.7|spu:592172|centromere protein F GO:0005815//microtubule organizing center;GO:0044427//chromosomal part - GO:0022402//cell cycle process 34959 811.00 0.82 0.35 -1.22826898767312 Down 0.246004490820235 CG13258 CG13258, isoform B - - - - 19834871 270.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 2768833 607.00 1.505 0.4 -1.91169158187234 Down 0.397107383436798 CG33468 CG33468 - - - - 34251 2982.29 266.995 259.425 -0.0414952104667976 Down 0.137663452648263 Eaat1 excitatory amino acid transporter 1, isoform D K05614|1|9e-100|365|dre:323439|solute carrier family 1 (glial high affinity glutamate transporter), member 3;K05617|3|6e-97|355|dre:559270|solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0033267//axon part;GO:0031224//intrinsic to membrane;GO:0045202//synapse;GO:0033267//axon part GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity GO:0015711//organic anion transport;GO:0010259//multicellular organismal aging;GO:0046942//carboxylic acid transport;GO:0014852;GO:0015711//organic anion transport;GO:0010259//multicellular organismal aging;GO:0046942//carboxylic acid transport;GO:0014852;GO:0015711//organic anion transport;GO:0010259//multicellular organismal aging;GO:0046942//carboxylic acid transport;GO:0014852;GO:0015711//organic anion transport;GO:0010259//multicellular organismal aging;GO:0046942//carboxylic acid transport;GO:0014852 38732 2857.00 3.22 2.335 -0.463638138404955 Down 0.281865011227051 CG42747 CG42747 - - - - 44173 569.00 19.25 16.21 -0.247974354952085 Down 0.382842425042927 hoip hoi-polloi, isoform B K12845|1|1e-48|192|dya:Dyak_GE18862|U4/U6 small nuclear ribonucleoprotein SNU13 GO:0005681//spliceosomal complex GO:0003723//RNA binding GO:0000377;GO:0007399//nervous system development;GO:0022613//ribonucleoprotein complex biogenesis 36757 1280.00 21.265 21.325 0.00406488657988877 Up 0.0444128912957337 CG8314 CG8314 - - GO:0016491//oxidoreductase activity;GO:0046914//transition metal ion binding - 317864 787.00 0.85 0.67 -0.343301745679929 Down 0.119171839915467 CG32117 CG32117 - - - - 38044 788.03 24.72 25.71 0.0566508669292817 Up 0.149484876502444 wac wee augmin, isoform D - GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007126//meiosis;GO:0007051//spindle organization;GO:0007126//meiosis;GO:0007051//spindle organization 31222 645.42 42.01 28.755 -0.546919948097211 Down 0.616794346849822 mRpL14 mitochondrial ribosomal protein L14, isoform B - - - - 43542 4129.33 530.875 849.275 0.677859578587038 Up 0.69369964337604 trp transient receptor potential, isoform B K05328|1|0.0|1977|dme:Dmel_CG7875|transient receptor potential cation channel subfamily C, invertebrate GO:0016028//rhabdomere;GO:0005891//voltage-gated calcium channel complex GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0005217//intracellular ligand-gated ion channel activity GO:0033036;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0009586;GO:0008306//associative learning;GO:0070838//divalent metal ion transport 33807 4003.60 16.39 13.78 -0.250239966395167 Down 0.368346321489896 CG9171 CG9171, isoform G K00741|1|2e-112|407|dme:Dmel_CG15483|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149] - GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity GO:0002118//aggressive behavior;GO:0002118//aggressive behavior;GO:0002118//aggressive behavior 43609 528.00 23.07 26.12 0.179136892863448 Up 0.333212257297583 mRpS18C mitochondrial ribosomal protein S18C K10600|1|2e-40|164|cqu:CpipJ_CPIJ003174|U-box domain-containing protein 5 GO:0043234//protein complex;GO:0030529//ribonucleoprotein complex GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0032446//protein modification by small protein conjugation 19835436 666.00 0.255 0.305 0.258311995591391 Up 0.0686501122705059 39566 3399.00 0.46 1.555 1.75720881407359 Up 0.393078853520011 Fbp1 Fat body protein 1, isoform D - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0022892;GO:0022892 GO:0017038//protein import;GO:0017038//protein import 43613 2164.00 0.11 0.545 2.30875270613963 Up 0.260533615110289 CG15534 CG15534 K12350|1|7e-89|328|phu:Phum_PHUM427830|sphingomyelin phosphodiesterase [EC:3.1.4.12] - GO:0004620//phospholipase activity GO:0006684//sphingomyelin metabolic process 19835002 1149.00 0.47 0.35 -0.425305834732671 Down 0.102925637300225 34727 863.00 3.195 2.205 -0.535037275389474 Down 0.306795667679303 CG15479 CG15479 - - - - 31170 5230.00 12.39 16.98 0.454660271412437 Up 0.510500594373266 Sik2 Salt-inducible kinase 2 K08286|1|0.0|1852|dme:Dmel_CG4290|protein-serine/threonine kinase [EC:2.7.11.-] - - - 38240 914.96 85.185 59.62 -0.514803037154849 Down 0.629276185444459 Cpr62Bb cuticular protein 62Bb, isoform C - - GO:0005198//structural molecule activity;GO:0005198//structural molecule activity - 170887 1233.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 CG31750 CG31750 - - GO:0004930//G-protein coupled receptor activity - 34976 1726.02 31.73 26.82 -0.242538284013164 Down 0.411900673623035 CaBP1 calcium-binding protein 1, isoform B K09584|1|0.0|747|dme:Dmel_CG5809|protein disulfide-isomerase A6 [EC:5.3.4.1] GO:0044444//cytoplasmic part GO:0003824//catalytic activity GO:0019725//cellular homeostasis 39662 3091.46 7.525 4.005 -0.909889339238354 Down 0.544577994980848 CG7255 CG7255, isoform I K13864|1|9e-122|438|bta:538708|solute carrier family 7 (cationic amino acid transporter), member 2 GO:0005681//spliceosomal complex;GO:0031224//intrinsic to membrane;GO:0005681//spliceosomal complex;GO:0031224//intrinsic to membrane;GO:0005681//spliceosomal complex;GO:0031224//intrinsic to membrane;GO:0005681//spliceosomal complex;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0000377;GO:0006865//amino acid transport;GO:0000377;GO:0006865//amino acid transport;GO:0000377;GO:0006865//amino acid transport;GO:0000377;GO:0006865//amino acid transport 192481 1194.00 0.04 0.075 0.906890595608519 Up 0.0698718795403513 Gr59c gustatory receptor 59c K08471|1|0.0|755|dme:Dmel_CG30186|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 39359 839.00 1.49 3.15 1.08003949792512 Up 0.435741645753533 CG14125 CG14125, isoform B - - - GO:0005976//polysaccharide metabolic process 31831 753.72 150.615 130.22 -0.209914413953546 Down 0.431448949940563 CG7267 CG44325, isoform E - - - - 40386 3139.70 64.35 54.43 -0.24153811238297 Down 0.445581825386343 CG7611 CG7611, isoform J K13111|1|8e-18|93.6|dvi:Dvir_GJ22777|WD40 repeat-containing protein SMU1 GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part - - 44819 3953.45 19.615 24.115 0.2979734746848 Up 0.449478272355039 g garnet, isoform F K12396|1|0.0|1666|dme:Dmel_CG10986|AP-3 complex subunit delta-1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0022892 GO:0015031//protein transport 5740861 603.00 6.265 8.7 0.47370089141423 Up 0.435015189539031 CG34234 CG34234 - - GO:0015929//hexosaminidase activity;GO:0043167//ion binding GO:0044238//primary metabolic process 14462860 317.00 0.01 0.16 4 Up 0.178939373926826 CG43678 CG43678 - - - - 36978 6332.28 26.95 28.94 0.102779648891856 Up 0.22358341038172 Patronin patronin, isoform O - - GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007052//mitotic spindle organization;GO:0007052//mitotic spindle organization 14462892 1537.00 23.475 25.03 0.0925331331471949 Up 0.199544313829085 40539 1502.00 12.265 10.645 -0.204371284105308 Down 0.293455289922071 CG9766 CG9766 K10380|1|4e-15|82.8|dpe:Dper_GL18390|ankyrin - - - 44830 6269.84 6.73 8.12 0.270873222574859 Up 0.305705983357549 kto kohtalo, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0016251//general RNA polymerase II transcription factor activity GO:0016055//Wnt receptor signaling pathway;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 33859 1491.00 60.245 55.93 -0.107219180321424 Down 0.262547880068683 Kr-h2 kruppel homolog 2, isoform C K11089|1|4e-22|71.2|dgr:Dgri_GH24936|60 kDa SS-A/Ro ribonucleoprotein GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 19834937 4168.00 0.36 0.83 1.20511442990461 Up 0.245112930920618 - CG45075 - - - - 39129 1427.00 14.54 16.12 0.148824474608373 Up 0.260335490688152 CG16717 CG16717 - - GO:0003824//catalytic activity - 3772107 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 31229 3860.84 1.22 1.915 0.650463244362071 Up 0.267203803988905 boi brother of ihog, isoform G K06755|1|1e-25|119|dre:30770|roundabout, axon guidance receptor 3;K06766|3|1e-25|119|mcc:705160|neogenin - - GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway 326122 1534.00 2.895 2.75 -0.0741317295772145 Down 0.0762779025227843 rumi rumi, isoform B K13667|1|0.0|824|dme:Dmel_CG31152|protein glucosyltransferase [EC:2.4.1.-] GO:0044432//endoplasmic reticulum part GO:0035251//UDP-glucosyltransferase activity GO:0008593//regulation of Notch signaling pathway;GO:0006486//protein glycosylation 43433 3058.00 3.62 3.615 -0.00199405013208751 Down 0.0382380134724607 Sirt7 Sirt7 K11417|1|0.0|1365|dme:Dmel_CG11305|NAD-dependent deacetylase sirtuin 7 [EC:3.5.1.-] - GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0046914//transition metal ion binding;GO:0051287//NAD binding GO:0016458//gene silencing;GO:0006464//cellular protein modification process 37586 1476.00 13.565 14.43 0.0891822522093321 Up 0.17157574957073 Cdk9 Cyclin-dependent kinase 9 K02211|1|0.0|765|dme:Dmel_CG5179|cyclin-dependent kinase 9 [EC:2.7.11.22] GO:0008023//transcription elongation factor complex;GO:0005700//polytene chromosome GO:0004674//protein serine/threonine kinase activity;GO:0003711//transcription elongation regulator activity;GO:0032559 GO:0065008;GO:0010467//gene expression;GO:0006950//response to stress;GO:0006464//cellular protein modification process 41518 2604.00 8.065 7.955 -0.0198126028245951 Down 0.0598335754854048 lig3 DNA ligase III K10776|1|0.0|1510|dme:Dmel_CG17227|DNA ligase 3 [EC:6.5.1.1] - - - 41661 532.58 3.65 8.22 1.1712419299143 Up 0.598302734117026 CG9759 CG9759, isoform C - - - - 38432 1708.00 0.05 0.14 1.48542682717024 Up 0.105402192576938 ImpE2 Ecdysone-inducible gene E2 - GO:0044464//cell part - - 40458 874.00 19.36 20.175 0.0594897208905479 Up 0.142451459516576 CG11523 CG11523 - - - - 35708 1210.00 13.6 25.33 0.897240425574799 Up 0.661669528463875 CG2064 CG2064 K00100|1|1e-114|412|dme:Dmel_CG2070| [EC:1.1.1.-];K11161|2|3e-81|301|bta:508082|retinol dehydrogenase 13 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 43754 3032.00 5.075 6.77 0.415748011502458 Up 0.371912561088364 CG42233 CG42233 K11800|1|0.0|790|dpo:Dpse_GA15250|WD repeat-containing protein 22 - - - 38478 1947.00 22.12 22.165 0.0029319769305577 Up 0.0441487253995509 Rcd5 reduction in Cnn dots 5 K11674|1|0.0|947|dme:Dmel_CG1135|microspherule protein 1 GO:0043231//intracellular membrane-bounded organelle - GO:0007017//microtubule-based process 37063 5070.07 8.13 10.725 0.39965039031188 Up 0.42887333245278 CG5098 CG5098, isoform C K09186|1|8e-09|63.9|spu:579728|myeloid/lymphoid or mixed-lineage leukemia protein 1/4;K09188|4|4e-07|58.2|dre:560793|myeloid/lymphoid or mixed-lineage leukemia protein 3 - - - 31720 1823.00 0.21 0.255 0.280107919192735 Up 0.0694426099590543 CG15333 CG15333 - - - - 41165 1295.00 6.755 5.28 -0.355417839967231 Down 0.340608902390701 CG8319 CG8319 K09228|1|9e-43|174|mmu:666581|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19836103 344.00 0.535 0.145 -1.88348599127357 Down 0.238872011623299 31877 3673.28 0.39 0.745 0.933766301599913 Up 0.204101175538238 Erk7 extracellularly regulated kinase 7, isoform C K08293|1|0.0|790|dme:Dmel_CG32703|mitogen-activated protein kinase [EC:2.7.11.24] - GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 37709 1299.31 270.655 289.985 0.099523235934985 Up 0.263076211861049 CG9812 CG9812, isoform E - - - - 37985 2859.79 23.03 16.91 -0.445637751382862 Down 0.539261656320169 pain painless, isoform C K04984|1|6e-15|83.6|cel:C29E6.2|transient receptor potential cation channel subfamily A member 1 GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity GO:0060180//female mating behavior;GO:0050906//detection of stimulus involved in sensory perception;GO:0009266//response to temperature stimulus;GO:0070838//divalent metal ion transport;GO:0006950//response to stress;GO:0009605//response to external stimulus 35083 3133.00 156.45 175.125 0.162683392077259 Up 0.364218729362039 CG5758 CG5758, isoform F - - - - 37555 1977.00 18.355 23.405 0.350643650612407 Up 0.48586712455422 wrapper wrapper K06766|1|7e-23|109|mdo:100029182|neogenin;K06491|3|1e-20|101|dre:30447|neural cell adhesion molecule GO:0016020//membrane - GO:0048667//cell morphogenesis involved in neuron differentiation 40517 3043.54 60.07 61.08 0.0240553982703817 Up 0.0881653678510104 alpha-Cat alpha catenin, isoform B K05691|1|0.0|1719|dse:Dsec_GM22485|catenin (cadherin-associated protein), alpha GO:0005856//cytoskeleton;GO:0005913//cell-cell adherens junction;GO:0016323//basolateral plasma membrane;GO:0019897//extrinsic to plasma membrane GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding GO:0007293//germarium-derived egg chamber formation;GO:0007010//cytoskeleton organization 31648 1424.00 1.21 0.88 -0.459431618637297 Down 0.170981376304319 CG3032 CG3032, isoform B K09228|1|2e-39|163|cfa:484247|KRAB domain-containing zinc finger protein - - - 19835245 716.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 31270 1843.07 21.96 27.825 0.341503633224123 Up 0.493131686699247 CG32795 CG32795, isoform E - - - - 34655 751.18 37.25 41.86 0.168331886018823 Up 0.344637432307489 CG5446 CG5446, isoform C - - - GO:0050896//response to stimulus 246651 1599.71 3.45 4.795 0.474934453352599 Up 0.345661075155197 CG30495 CG30495, isoform B K00100|1|8e-98|357|dme:Dmel_CG2070| [EC:1.1.1.-];K11153|2|1e-68|260|tgu:100226769|retinol dehydrogenase 12 [EC:1.1.1.-];K11161|4|7e-67|254|cfa:611373|retinol dehydrogenase 13 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 42773 2462.01 46.58 10.705 -2.12142584382536 Down 0.772156914542333 CG10175 CG10175, isoform E K03927|1|8e-78|292|dvi:Dvir_GJ10232|carboxylesterase type B [EC:3.1.1.1];K01044|3|6e-75|282|dpo:Dpse_GA10768|carboxylesterase [EC:3.1.1.1] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - 37081 1473.98 13.41 11.645 -0.203598597693608 Down 0.303031303658698 CG10916 CG10916, isoform B K11985|1|1e-08|60.5|ame:726290|TRAF-interacting protein - - - 36957 1188.00 2.655 2.9 0.127341039210781 Up 0.112237485140668 Lhr lethal hybrid rescue - - - - 36064 4226.80 154.365 161.52 0.0653671360414615 Up 0.197761194029851 gem gemini, isoform G K09275|1|0.0|1494|dme:Dmel_CG30011|transcription factor CP2 and related proteins - GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 19836211 422.00 0.22 0.14 -0.652076696579693 Down 0.09047681944261 33295 999.00 19.675 21.395 0.120910043228641 Up 0.239235239730551 CG4764 vacuolar protein sorting 29 K07095|1|1e-102|372|dya:Dyak_GE17363| GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016791//phosphatase activity GO:0006810//transport;GO:0006796//phosphate-containing compound metabolic process 19834803 401.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 35263 1254.00 9.39 8.32 -0.174541629512682 Down 0.238343679830934 CG10628 CG10628 K03979|1|3e-43|176|xla:779190|GTP-binding protein GO:0031981//nuclear lumen GO:0032561//guanyl ribonucleotide binding GO:0022613//ribonucleoprotein complex biogenesis 34230 1088.22 0.995 0.555 -0.842208754193543 Down 0.220776647734777 CG9582 CG9582, isoform B K03454|1|6e-24|111|xla:443984|mitochondrial carrier protein, MC family GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006810//transport;GO:0048102//autophagic cell death 19836229 272.00 0.345 0.685 0.989507626182358 Up 0.198619733192445 43177 2266.72 28.42 27.46 -0.0495749290956797 Down 0.135352001056664 CG31324 CG31324, isoform C - - - - 41056 1207.00 3.43 3.445 0.00629540653147891 Up 0.0432901862369568 CG8359 hinge2 K05544|1|6e-09|62.0|bmy:Bm1_16415|tRNA-dihydrouridine synthase 3 [EC:1.-.-.-] - GO:0003676//nucleic acid binding - 19835931 901.00 3.705 6.35 0.777283049353694 Up 0.490457007000396 42557 2945.00 0.925 1.125 0.282399730700725 Up 0.118676528860124 CG31233 CG31233 K11140|1|0.0|1847|dme:Dmel_CG31233|aminopeptidase N [EC:3.4.11.2] - GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 50416 1031.00 39.695 14.035 -1.49992823244748 Down 0.73864086646414 CG12643 CG12643 - - - - 37096 599.00 2.63 0.935 -1.49202452940467 Down 0.45991282525426 CG18539 CG18539, isoform C - - - - 326250 593.43 21.015 22.715 0.112225848904768 Up 0.228536520935147 CG34148 CG34148, isoform C - GO:0031980 GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0006560//proline metabolic process 41113 1404.50 17.49 14.27 -0.293544954445889 Down 0.413287544577995 CG8121 CG8121, isoform C K00670|1|4e-24|112|dwi:Dwil_GK15295|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - - - 35770 4701.47 13.22 14.535 0.136808894628546 Up 0.240291903315282 CG12769 CG12769, isoform C K09220|1|6e-81|302|nvi:100117948|IKAROS family zinc finger protein - GO:0005488//binding;GO:0005488//binding - 31660 6808.84 2.46 2.7 0.134301091711591 Up 0.109496763967772 CG9650 CG9650, isoform J K09228|1|1e-16|89.7|hsa:56242|KRAB domain-containing zinc finger protein - - - 41704 3043.46 47.3 45.255 -0.0637629863588992 Down 0.16728305375776 rdx roadkill, isoform F K10523|1|0.0|746|dpo:Dpse_GA22127|speckle-type POZ protein - - - 5740746 297.84 198.155 170.55 -0.216434616009365 Down 0.446275260863822 CG34172 CG34172, isoform D K02270|1|3e-06|49.7|cfa:612614|cytochrome c oxidase subunit VIIa [EC:1.9.3.1] GO:0005743//mitochondrial inner membrane GO:0015002//heme-copper terminal oxidase activity - 8673979 527.00 0.16 0.265 0.727920454563199 Up 0.104444591203276 CG42470 CG42470 - - - - 39672 1520.36 21.665 22.485 0.053596647397147 Up 0.131125346717739 CG7841 CG7841, isoform B - - - - 36030 1427.00 12.93 14.385 0.153842945929033 Up 0.254094571390833 Fmrf FMRFamide - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0008016//regulation of heart contraction 34550 1276.00 4.21 3.355 -0.327507466866212 Down 0.261227050587769 RfC38 replication factor C 38kD subunit, isoform B K10756|1|0.0|701|dme:Dmel_CG6258|replication factor C subunit 3/5 GO:0042575;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032559;GO:0034061 GO:0006259//DNA metabolic process 19835396 570.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 30996 1121.71 28.94 30.03 0.0533395530254251 Up 0.138654074758949 CG17778 CG17778, isoform B - - - - 31689 622.00 0.325 0.29 -0.164386817900882 Down 0.0596684718002906 CG1409 CG1409 - - - - 38835 2089.00 2.095 1.935 -0.114616677554941 Down 0.0881653678510104 CG8546 pickpocket 26 K04832|1|1e-48|194|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04829|4|2e-15|84.3|spu:575477|amiloride-sensitive cation channel 2, neuronal GO:0031224//intrinsic to membrane GO:0005272//sodium channel activity GO:0030001//metal ion transport 41623 1869.00 104.765 32.695 -1.68001489191244 Down 0.768260467573636 CG8483 CG8483 - - - - 14462430 879.00 11.45 11.935 0.0598509680974703 Up 0.122672038039889 41747 3308.26 13.225 16.115 0.285136466058157 Up 0.4024567428345 NK7.1 NK7.1, isoform C K09349|1|1e-16|89.0|smm:Smp_013600|homeobox protein Nkx-5 - - - 12797901 400.00 2.185 0.15 -3.86459887389208 Down 0.568088759741117 CG43291 CG43291, isoform B - - - - 19835994 1297.00 0.155 0.275 0.827163403137785 Up 0.111478008189143 38367 2356.00 121.36 132.115 0.122501285100385 Up 0.294445912032757 CG32486 CG32486 K04506|1|3e-12|74.3|smm:Smp_000650|E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19];K08742|3|5e-12|73.6|dre:378728|E3 ubiquitin-protein ligase SIAH2 [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0019941//modification-dependent protein catabolic process;GO:0032501//multicellular organismal process;GO:0032446//protein modification by small protein conjugation 261615 642.90 2.755 1.29 -1.0946812531479 Down 0.414047021529521 CG31806 CG31806, isoform B - - - - 38190 3944.60 1.575 1.085 -0.537656785942799 Down 0.216186765288601 CG12105 CG12105, isoform B K00164|1|3e-09|65.5|dme:Dmel_CG33791|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] - - - 38274 1389.00 2.445 2.395 -0.0298088092160536 Down 0.0530643243957205 CG15879 CG15879 K01175|1|2e-26|120|mmu:68607| [EC:3.1.-.-] - - - 43567 619.00 12.005 16.905 0.493814612662961 Up 0.527506273940034 ocn ocnus K01112|1|3e-09|61.6|gga:424401| [EC:3.1.3.-] - - GO:0003006//developmental process involved in reproduction 38471 1372.00 0.035 0.065 0.893084796083488 Up 0.0629375247655528 fd64A forkhead domain 64A, isoform B K09411|1|0.0|701|dme:Dmel_CG1132|forkhead box protein, other GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0016564//transcription repressor activity GO:0000278//mitotic cell cycle;GO:0045596//negative regulation of cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016198//axon choice point recognition;GO:0001708//cell fate specification;GO:0007405//neuroblast proliferation;GO:0051726//regulation of cell cycle;GO:0009790//embryo development;GO:0042384//cilium assembly;GO:0007379//segment specification 33532 2270.40 42.045 52.76 0.327510319497894 Up 0.52235503896447 Hydr2 alpha/beta hydrolase2, isoform C K13697|1|0.0|820|dme:Dmel_CG3488|abhydrolase domain-containing protein 2 - GO:0016788//hydrolase activity, acting on ester bonds - 19834997 1938.00 0.625 0.255 -1.29335894269059 Down 0.219026548672566 19835833 593.00 0.29 1.76 2.60145062350973 Up 0.469191652357681 38384 5079.00 3.525 2.905 -0.279085093881627 Down 0.213181878219522 CG14964 CG14964 K12567|1|7e-51|203|ssc:100156443|titin [EC:2.7.11.1] - - - 39489 699.00 1.305 1.67 0.355798295904167 Up 0.172236164311187 CG17300 CG17300 K02127|1|6e-14|77.4|der:Dere_GG15409|F-type H+-transporting ATPase subunit b [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006810//transport;GO:0006754//ATP biosynthetic process 35349 2570.00 0.375 0.735 0.970853654340484 Up 0.204992735437855 Oseg5 outer segment 5 K00567|1|2e-08|61.2|xla:446289|methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63];K11293|2|3e-07|57.8|xla:394341|protein HIRA/HIR1;K03130|4|4e-06|53.9|phu:Phum_PHUM362800|transcription initiation factor TFIID subunit D4 - - - 36806 3571.78 2.385 2.685 0.170932821979901 Up 0.131158367454762 Cng cyclic nucleotide-gated ion channel subunit A, isoform B K05326|1|0.0|1179|dme:Dmel_CG7779|cyclic nucleotide gated channel, invertebrate GO:0034703//cation channel complex;GO:0034703//cation channel complex GO:0005217//intracellular ligand-gated ion channel activity;GO:0005217//intracellular ligand-gated ion channel activity GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006811//ion transport;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006811//ion transport 36425 2753.45 16.41 18.105 0.141812937962465 Up 0.258288204992735 CG17019 CG17019, isoform B K10871|1|1e-28|128|tgu:100223360|RAD51-like protein 3;K04725|2|3e-09|64.7|tca:663905|baculoviral IAP repeat-containing 2/3/4;K10641|3|1e-08|62.4|tad:TRIADDRAFT_53391|E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 8674117 300.00 0.75 0.84 0.163498732282879 Up 0.0773675868445384 CG42464 CG42464 K06238|1|3e-07|53.1|dre:564005|collagen, type VI, alpha - - - 33255 2415.03 4.075 5.065 0.313762209682698 Up 0.275095760137366 Saf6 SAGA factor-like TAF6, isoform B - - - - 3772069 3866.04 2.675 3.73 0.479636738966729 Up 0.310328886540748 mus201 mutagen-sensitive 201, isoform D K10846|1|0.0|2229|dme:Dmel_CG10890|DNA excision repair protein ERCC-5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043566//structure-specific DNA binding;GO:0004520//endodeoxyribonuclease activity;GO:0043566//structure-specific DNA binding;GO:0004520//endodeoxyribonuclease activity GO:0006281//DNA repair;GO:0006281//DNA repair 36762 656.00 50.385 40.83 -0.303364728730504 Down 0.496929071456875 CG8386 CG8386 K12165|1|6e-95|346|dya:Dyak_GE14107|ufm1-conjugating enzyme 1 - GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation 326259 2512.00 10.92 12.475 0.192066959304771 Up 0.284737815348039 CG33116 CG33116 K00993|1|0.0|866|dme:Dmel_CG33116|ethanolaminephosphotransferase [EC:2.7.8.1] GO:0044464//cell part GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006909//phagocytosis;GO:0006644//phospholipid metabolic process 35779 2863.00 26.01 23.765 -0.130227997640655 Down 0.266246202615242 CG11210 CG11210 K00728|1|2e-13|78.6|ssc:100155173|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] GO:0044464//cell part - - 37719 1052.00 0.115 0.085 -0.436099114806673 Down 0.0616827367586845 CG13558 CG13558 - - - - 31555 8762.10 22.165 28.8 0.37778544916441 Up 0.520836085061419 CG14446 CG14446, isoform E - - - - 40001 825.00 20.005 22.75 0.185505916627819 Up 0.334764231937657 mRpS26 mitochondrial ribosomal protein S26 - GO:0000314//organellar small ribosomal subunit GO:0005198//structural molecule activity - 41555 1330.00 0.15 0.13 -0.206450877467426 Down 0.0516774534407608 CG11600 CG11600 K01046|1|2e-65|249|dme:Dmel_CG8093|triacylglycerol lipase [EC:3.1.1.3];K01066|2|2e-59|229|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-] - - - 37596 677.05 2.25 2.545 0.177740654858658 Up 0.129804517236825 CG13510 CG13510, isoform C - - - - 32318 2955.00 17.08 14.725 -0.214040340902667 Down 0.335457667415137 tth toothrin, isoform C K13196|1|6e-33|143|dmo:Dmoj_GI20660|zinc finger protein ubi-d4 - GO:0046872//metal ion binding - 39277 782.00 1.005 1.02 0.021373650792567 Up 0.0440166424514595 CG6149 CG6149 - GO:0031224//intrinsic to membrane - - 42062 2819.62 8.23 7.255 -0.181916816354881 Down 0.233489631488575 Keap1 Keap1, isoform C K10456|1|0.0|1500|dme:Dmel_CG3962|kelch-like protein 19 - - - 34908 1668.00 0.08 0.01 -3 Down 0.110718531237617 sna snail K09218|1|0.0|652|dme:Dmel_CG3956|snail, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0016564//transcription repressor activity GO:0010004//gastrulation involving germ band extension;GO:0007267//cell-cell signaling;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048333//mesodermal cell differentiation;GO:0001708//cell fate specification;GO:0001654//eye development;GO:0009798//axis specification;GO:0001709//cell fate determination;GO:0007447//imaginal disc pattern formation 45398 2000.73 120.97 100.76 -0.263726282980298 Down 0.481805573900409 Aldh-III aldehyde dehydrogenase type III, isoform U K00129|1|3e-155|548|dme:Dmel_CG11140|aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5];K00128|2|2e-142|506|nve:NEMVE_v1g170078|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process 5740791 327.00 0.14 1.27 3.18132976471456 Up 0.436071853123762 CG41527 CG41527 K12559|1|1e-08|58.2|oaa:100079898|myosin X GO:0043232 GO:0005488//binding GO:0023060 33972 3276.00 3.03 2.065 -0.553176012053506 Down 0.304616299035794 ihog interference hedgehog K06766|1|1e-23|112|mcc:705160|neogenin GO:0031224//intrinsic to membrane GO:0042802//identical protein binding;GO:0005539//glycosaminoglycan binding GO:0008589//regulation of smoothened signaling pathway;GO:0007447//imaginal disc pattern formation 42862 3896.00 12.44 13.72 0.14129399604221 Up 0.237617223616431 Tsc1 Tsc1 K07206|1|0.0|1962|dme:Dmel_CG6147|tuberous sclerosis 1 GO:0044424//intracellular part GO:0019899//enzyme binding GO:0045926//negative regulation of growth;GO:0044238//primary metabolic process;GO:0016049//cell growth;GO:0023060;GO:0007049//cell cycle;GO:0031667//response to nutrient levels;GO:0010259//multicellular organismal aging;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008283//cell proliferation;GO:0040034//regulation of development, heterochronic;GO:0035467 31415 860.00 0.095 0.105 0.144389909335175 Up 0.0448421608770308 CG12682 CG12682 - GO:0044464//cell part GO:0046914//transition metal ion binding - 39088 535.00 1010.595 940.805 -0.103237314585575 Down 0.266873596618677 RpS17 ribosomal protein S17 K02962|1|2e-60|231|dmo:Dmoj_GI13264|small subunit ribosomal protein S17e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 34567 787.46 7.47 9.05 0.276809549181331 Up 0.325584467045304 CG14926 CG14926, isoform C - - - - 8674065 496.00 1.285 2.6 1.01674326383458 Up 0.393739268260468 19835323 1321.00 0.205 0.035 -2.55019708256048 Down 0.155923920221899 38204 1257.00 53.395 53.67 0.00741123632801808 Up 0.0634658565579184 CG7967 CG7967 K12199|1|2e-133|475|dme:Dmel_CG7967|vacuolar protein sorting-associated protein VTA1 - - - 32631 3269.00 18.44 18.145 -0.0232665989500037 Down 0.0758156122044644 mbt mushroom bodies tiny K08286|1|1e-172|607|dme:Dmel_CG18582|protein-serine/threonine kinase [EC:2.7.11.-];K05736|3|1e-138|494|rno:311450|p21-activated kinase 7 [EC:2.7.11.1] GO:0070161;GO:0005911//cell-cell junction GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0006996//organelle organization;GO:0000165//MAPK cascade;GO:0001745//compound eye morphogenesis;GO:0042479;GO:0006464//cellular protein modification process 38693 464.39 10.11 7.45 -0.440470666553491 Down 0.442048606524898 CG6610 CG6610, isoform C K12624|1|1e-46|185|dya:Dyak_GE21536|U6 snRNA-associated Sm-like protein LSm5 GO:0030529//ribonucleoprotein complex GO:0005488//binding GO:0000377 36850 2294.89 11.3 5.7 -0.987288948250446 Down 0.607845727116629 CG4945 CG4945, isoform D K08858|1|0.0|918|dme:Dmel_CG4945|SH3-binding domain kinase 1 [EC:2.7.11.1] - - - 40004 1436.00 1.455 2.555 0.812304138029337 Up 0.347873464535728 CG7341 CG7341, isoform B - - - - 41206 3515.00 10.8 11.36 0.0729315224538511 Up 0.134295337471932 CG8516 CG8516 - - - - 2768674 4587.00 0.585 1.29 1.14086253583985 Up 0.298573504160613 Fancd2 Fancd2 K10891|1|0.0|2701|dme:Dmel_CG17269|fanconi anemia group D2 protein - GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process 32731 2070.40 1.19 1.005 -0.243766072129015 Down 0.107944789327698 ppk23 pickpocket 23, isoform D K04832|1|5e-13|75.9|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal;K04828|2|4e-08|59.7|nve:NEMVE_v1g80340|amiloride-sensitive cation channel 1, neuronal (degenerin) GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005261//cation channel activity;GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0002118//aggressive behavior;GO:0030001//metal ion transport;GO:0002118//aggressive behavior;GO:0030001//metal ion transport;GO:0002118//aggressive behavior;GO:0030001//metal ion transport 43059 1301.00 3.945 2.32 -0.765900494885887 Down 0.409589222031436 CG13659 CG13659 - - - - 38983 619.00 936.865 937.795 0.00143141316088672 Up 0.0473187161537445 RpL14 ribosomal protein L14 K02875|1|3e-84|310|dme:Dmel_CG6253|large subunit ribosomal protein L14e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process 31632 1157.97 5.83 7.075 0.279234264518748 Up 0.296162990357945 CG14434 CG14434, isoform C K01768|1|4e-73|274|dpo:Dpse_GA12981|adenylate cyclase [EC:4.6.1.1] - - - 38508 1014.00 25.045 11.995 -1.06208945396447 Down 0.682010302469951 Cpr64Aa cuticular protein 64Aa - - GO:0042302//structural constituent of cuticle - 48844 1840.03 28.94 26.235 -0.141572131888916 Down 0.287709681680095 l(2)tid lethal (2) tumorous imaginal discs, isoform E K09504|1|0.0|815|dme:Dmel_CG5504|DnaJ homolog subfamily A member 3;K09523|2|2e-180|632|dmo:Dmoj_GI19741|DnaJ homolog subfamily C member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005739//mitochondrion GO:0043169//cation binding;GO:0005102//receptor binding;GO:0032559;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0032559;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0032559 GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0044267//cellular protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0044267//cellular protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0044267//cellular protein metabolic process 37784 1593.00 119.41 108.16 -0.142756603540829 Down 0.328919561484612 Thiolase thiolase K07509|1|0.0|884|dme:Dmel_CG4581|acetyl-CoA acyltransferase [EC:2.3.1.16] GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0009062//fatty acid catabolic process 31915 5360.44 5.855 5.435 -0.107389135473906 Down 0.138389908862766 CG32698 CG32698, isoform D K01672|1|3e-42|173|ptr:740899|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 36664 1801.00 90.295 98.45 0.124745104078729 Up 0.289922071060626 Cyp6a20 Cyp6a20 K00517|1|0.0|894|dme:Dmel_CG10245| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 40488 862.00 0.185 0.26 0.490986352512142 Up 0.0886276581693303 CG14451 CG14451 - GO:0044464//cell part GO:0046914//transition metal ion binding - 38667 958.62 46.415 61.37 0.402942465009357 Up 0.570994584599128 CG32407 CG32407, isoform B K01104|1|2e-06|53.9|tad:TRIADDRAFT_54170|protein-tyrosine phosphatase [EC:3.1.3.48] - - - 14462739 875.00 0.055 0.01 -2.4594316186373 Down 0.0799432043323207 31947 1095.00 0.04 0.1 1.32192809488736 Up 0.0864152687887994 CG12645 CG12645, isoform C - - - - 35521 2084.00 32.695 2.455 -3.73527509363193 Down 0.824065513142253 CG7881 CG7881, isoform B K08193|1|2e-73|277|ame:410278|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport 41374 1851.00 11.15 6.605 -0.755413243560839 Down 0.563300752872804 CG6744 CG6744, isoform B K10900|1|8e-15|82.4|rno:290805|werner syndrome ATP-dependent helicase [EC:3.6.1.-] GO:0044464//cell part GO:0005488//binding;GO:0004527//exonuclease activity GO:0034641//cellular nitrogen compound metabolic process 35316 1710.60 54.22 39.4 -0.460629483493973 Down 0.595892220314357 CG2493 CG2493, isoform B K01285|1|0.0|917|dme:Dmel_CG2493|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 318843 2714.66 48.085 18.765 -1.35754262870594 Down 0.735702020869106 CG43394 CG43394, isoform E - - - - 38446 2190.42 14.465 14.555 0.00894851619316608 Up 0.053625676925109 CG12006 CG12006, isoform B K05286|1|0.0|976|dme:Dmel_CG12006|phosphatidylinositol glycan, class B [EC:2.4.1.-] GO:0005789//endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups GO:0006497//protein lipidation;GO:0006810//transport;GO:0006497//protein lipidation;GO:0006810//transport 33815 544.24 16.635 13.255 -0.327685196015607 Down 0.438680491348567 CG9029 CG9029, isoform B - - - - 41791 2071.00 1.32 0.715 -0.884522782580064 Down 0.263406419231277 CG14857 CG14857 K08202|1|3e-41|170|dmo:Dmoj_GI22094|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - - 40236 1440.00 3.78 17.455 2.20718221733168 Up 0.737782327301545 Spn77Bc serpin 77Bc, isoform B K03911|1|2e-21|103|mmu:11905|antithrombin III;K13963|2|9e-21|101|dan:Dana_GF19634|serpin B - GO:0004866//endopeptidase inhibitor activity - 37421 1828.76 21.65 32.645 0.592495016510538 Up 0.614846123365474 CG15661 CG15661, isoform B K00699|1|0.0|1035|dme:Dmel_CG15661|glucuronosyltransferase [EC:2.4.1.17] - - - 38608 2101.00 2.765 4.42 0.676766889156724 Up 0.400904768194426 CG4669 CG4669 - - - - 31071 7589.80 22.065 25.97 0.235086266702421 Up 0.39654603090741 CG3638 CG3638, isoform J - - - - 32688 7164.67 28.57 28.545 -0.00126297394119385 Down 0.0416061286487914 CG9059 CG45002, isoform J K01278|1|4e-90|334|phu:Phum_PHUM073920|dipeptidyl-peptidase 4 [EC:3.4.14.5] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 43425 1349.00 14.97 11.66 -0.36050643285792 Down 0.447926297714965 beta4GalNAcTB beta4GalNAcTB K07968|1|6e-51|201|dre:561756|beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-];K07966|2|1e-50|201|cin:100175041|beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-];K07967|5|7e-49|194|xla:100190782|beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0008376//acetylgalactosaminyltransferase activity GO:0006664//glycolipid metabolic process 19835387 346.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 41576 984.00 98.5 93.54 -0.0745402958121602 Down 0.194789327697794 CG31345 CG31345 K13448|1|7e-10|64.7|nve:NEMVE_v1g220271|calcium-binding protein CML;K02183|2|3e-09|62.8|mmu:80796|calmodulin - - - 42579 646.00 0.56 1.075 0.940837927531856 Up 0.245443138290847 CG17819 CG17819 K07977|1|8e-105|379|dme:Dmel_CG17819|Arf/Sar family, other;K07944|3|8e-28|123|dan:Dana_GF16955|ADP-ribosylation factor-like 3 - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity - 33984 1272.00 3.04 3.72 0.291231297664446 Up 0.225630696077136 CG43322 CG43322 K09504|1|2e-07|57.4|nve:NEMVE_v1g120890|DnaJ homolog subfamily A member 3 - GO:0005515//protein binding - 41001 1069.00 0.085 0.055 -0.628031222613042 Down 0.0622440892880729 CG7963 CG7963 K09228|1|1e-36|91.3|dre:555539|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 37129 4280.71 70.22 73.94 0.0744730473064882 Up 0.191883502839783 CG43066 CG43066, isoform C K05336|1|0.0|1301|dme:Dmel_CG5226|solute carrier family 6 (neurotransmitter transporter), invertebrate - - - 37945 846.00 0.7 0.585 -0.258918297361562 Down 0.0930524369303923 CG30161 CG30161 - - - - 37953 8297.00 24.53 28.67 0.224994670682922 Up 0.385979395060098 CG33988 Mid1 ortholog, isoform B - - - - 3772198 529.00 0.01 0.01 0 - 0.0382380134724607 His3:CG33818 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 2768939 1583.00 0.055 0.19 1.78849589480629 Up 0.133667943468498 CG33282 CG33282 K08145|1|2e-42|174|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane - GO:0006810//transport 39477 602.00 37.05 29.195 -0.343752231400714 Down 0.512382776383569 mRpL20 mitochondrial ribosomal protein L20 - GO:0000315//organellar large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression 43291 2808.38 22.285 23.085 0.0508827714367122 Up 0.130630035662396 mrt martik, isoform F - - - GO:0008306//associative learning 41372 773.00 176.94 173.36 -0.0294891696892193 Down 0.114119667150971 RpL24-like ribosomal protein L24-like K02896|1|4e-95|347|dme:Dmel_CG6764|large subunit ribosomal protein L24e GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 43572 1546.00 10.79 8.665 -0.316423210327847 Down 0.380035662395985 Sry-delta serendipity delta K09228|1|2e-27|124|ptr:454312|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0007292//female gamete generation;GO:0006351//transcription, DNA-dependent;GO:0000578//embryonic axis specification 12798571 1167.00 0.365 0.61 0.740912778682869 Up 0.155197464007397 31926 1528.70 522.225 410.05 -0.348871686701446 Down 0.575551446308282 Idgf4 imaginal disc growth factor 4, isoform C K01183|1|4e-44|179|dme:Dmel_CG9357|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding GO:0006032//chitin catabolic process;GO:0048513//organ development;GO:0006032//chitin catabolic process;GO:0048513//organ development 251916 597.00 0.14 0.01 -3.8073549220576 Down 0.163848897107383 CG32235 CG32235 - - - - 41862 1810.93 7.06 9.05 0.358249608699387 Up 0.383040549465064 Aats-ser Seryl-tRNA synthetase, isoform B K01875|1|0.0|748|dme:Dmel_CG4938|seryl-tRNA synthetase [EC:6.1.1.11] - - - 43110 1260.27 0.41 0.63 0.619727918881833 Up 0.142748646149782 CG17198 CG17198, isoform B - - GO:0046914//transition metal ion binding - 36775 1678.12 179.33 153.83 -0.221279970105005 Down 0.445383700964206 Rho1 Rho1, isoform G K04513|1|2e-101|370|dya:Dyak_GE11751|Ras homolog gene family, member A GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019899//enzyme binding GO:0007015//actin filament organization;GO:0007443//Malpighian tubule morphogenesis;GO:0035026//leading edge cell differentiation;GO:0007411//axon guidance;GO:0051301//cell division;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010927;GO:0035151//regulation of tube size, open tracheal system;GO:0016477//cell migration;GO:0035090//maintenance of apical/basal cell polarity;GO:0035148//tube formation;GO:0007276//gamete generation;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007391//dorsal closure;GO:0008360//regulation of cell shape;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0009855//determination of bilateral symmetry;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006582//melanin metabolic process;GO:0009611//response to wounding;GO:0007015//actin filament organization;GO:0007443//Malpighian tubule morphogenesis;GO:0035026//leading edge cell differentiation;GO:0007411//axon guidance;GO:0051301//cell division;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010927;GO:0035151//regulation of tube size, open tracheal system;GO:0016477//cell migration;GO:0035090//maintenance of apical/basal cell polarity;GO:0035148//tube formation;GO:0007276//gamete generation;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007391//dorsal closure;GO:0008360//regulation of cell shape;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0009855//determination of bilateral symmetry;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006582//melanin metabolic process;GO:0009611//response to wounding;GO:0007015//actin filament organization;GO:0007443//Malpighian tubule morphogenesis;GO:0035026//leading edge cell differentiation;GO:0007411//axon guidance;GO:0051301//cell division;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010927;GO:0035151//regulation of tube size, open tracheal system;GO:0016477//cell migration;GO:0035090//maintenance of apical/basal cell polarity;GO:0035148//tube formation;GO:0007276//gamete generation;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007391//dorsal closure;GO:0008360//regulation of cell shape;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0009855//determination of bilateral symmetry;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006582//melanin metabolic process;GO:0009611//response to wounding;GO:0007015//actin filament organization;GO:0007443//Malpighian tubule morphogenesis;GO:0035026//leading edge cell differentiation;GO:0007411//axon guidance;GO:0051301//cell division;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010927;GO:0035151//regulation of tube size, open tracheal system;GO:0016477//cell migration;GO:0035090//maintenance of apical/basal cell polarity;GO:0035148//tube formation;GO:0007276//gamete generation;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007391//dorsal closure;GO:0008360//regulation of cell shape;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0009855//determination of bilateral symmetry;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006582//melanin metabolic process;GO:0009611//response to wounding;GO:0007015//actin filament organization;GO:0007443//Malpighian tubule morphogenesis;GO:0035026//leading edge cell differentiation;GO:0007411//axon guidance;GO:0051301//cell division;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010927;GO:0035151//regulation of tube size, open tracheal system;GO:0016477//cell migration;GO:0035090//maintenance of apical/basal cell polarity;GO:0035148//tube formation;GO:0007276//gamete generation;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007391//dorsal closure;GO:0008360//regulation of cell shape;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0009855//determination of bilateral symmetry;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006582//melanin metabolic process;GO:0009611//response to wounding;GO:0007015//actin filament organization;GO:0007443//Malpighian tubule morphogenesis;GO:0035026//leading edge cell differentiation;GO:0007411//axon guidance;GO:0051301//cell division;GO:0048592//eye morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010927;GO:0035151//regulation of tube size, open tracheal system;GO:0016477//cell migration;GO:0035090//maintenance of apical/basal cell polarity;GO:0035148//tube formation;GO:0007276//gamete generation;GO:0035146;GO:0010004//gastrulation involving germ band extension;GO:0033554//cellular response to stress;GO:0001736//establishment of planar polarity;GO:0016192//vesicle-mediated transport;GO:0007391//dorsal closure;GO:0008360//regulation of cell shape;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007431//salivary gland development;GO:0000165//MAPK cascade;GO:0009855//determination of bilateral symmetry;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0006582//melanin metabolic process;GO:0009611//response to wounding 12797908 513.00 0.165 0.01 -4.04439411935845 Down 0.184883106590939 39201 683.00 0.295 0.33 0.161751069996612 Up 0.0596684718002906 CG14151 CG14151 - - - - 42180 885.00 8.74 11.6 0.408419620514336 Up 0.443633601901994 CG7988 CG7988 - - - - 14462472 931.00 0.52 0.79 0.603341030036011 Up 0.158565579183727 318616 721.00 1.89 2.35 0.314274522343927 Up 0.18871351208559 CG31174 CG31174, isoform B - - - - 31141 1990.70 22.42 22.34 -0.00515709232211196 Down 0.0526350548144235 Pex5 peroxin 5, isoform B K13342|1|0.0|1178|dse:Dsec_GM18948|peroxin-5 - - - 36218 1047.00 2.06 1.03 -1 Down 0.351010434552899 thetaTry thetaTrypsin K01312|1|5e-141|500|dme:Dmel_CG12385|trypsin [EC:3.4.21.4] GO:0044421//extracellular region part GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 246633 2435.00 0.08 0.025 -1.67807190511264 Down 0.0883304715361247 CG30471 CG30471 - - - - 34235 3378.00 0.09 0.05 -0.84799690655495 Down 0.0698718795403513 Toll-4 Toll-4 K06850|1|4e-21|104|dme:Dmel_CG8355|slit 3;K10160|2|2e-17|91.7|dre:403132|toll-like receptor 4;K05401|5|1e-15|86.3|spu:587154|toll-like recepto 3 GO:0031224//intrinsic to membrane GO:0004872//receptor activity;GO:0005488//binding GO:0006952//defense response;GO:0023060 36415 1070.41 27.495 28.005 0.0265151416863163 Up 0.09708096684718 CG17574 CG17574, isoform L - - - - 33874 864.48 13.105 20.93 0.675454957927292 Up 0.605897503632281 CG9486 CG9486, isoform B K00669|1|4e-12|72.0|dme:Dmel_CG3318|arylalkylamine N-acetyltransferase [EC:2.3.1.87] - GO:0016407//acetyltransferase activity - 33522 608.52 4.5 4.175 -0.108148803855623 Down 0.123200369832255 CG17261 CG17261, isoform B - - - - 19834848 478.00 0.18 0.295 0.712718047919529 Up 0.108605204068155 32815 6236.00 10.075 11.295 0.164904431977755 Up 0.245806366398098 CG6123 CG6123, isoform B - - - - 5740688 365.00 0.24 0.535 1.15650448567999 Up 0.191982565050852 RpS28-like ribosomal protein S28-like K02979|1|1e-14|77.8|dpe:Dper_GL26153|small subunit ribosomal protein S28e GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 3771834 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 50236 565.30 4.185 4.32 0.0458036896131247 Up 0.0716219786025624 CG18336 CG18336, isoform B - - - - 53436 6122.69 14.11 15.245 0.111618162412484 Up 0.204497424382512 c11.1 c11.1, isoform B - - - - 43547 2340.00 11.105 10.335 -0.103671004121533 Down 0.172566371681416 Cog7 Cog7 - - - - 32179 5846.00 0.33 0.52 0.656045598782639 Up 0.133866067890635 CG2750 CG2750, isoform C K10955|1|5e-06|55.1|tgu:100220116|intestinal mucin-2 - - - 43842 4922.77 59.25 62.99 0.0883076572123535 Up 0.226390173028662 CG11148 CG11148, isoform H - - - - 33716 1561.00 9.065 8.77 -0.0477301772994252 Down 0.0974772156914542 Gmd GDP-mannose 4,6-dehydratase K01711|1|0.0|800|dme:Dmel_CG8890|GDPmannose 4,6-dehydratase [EC:4.2.1.47] GO:0044464//cell part GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity GO:0006013//mannose metabolic process;GO:0042350//GDP-L-fucose biosynthetic process;GO:0021550//medulla oblongata development 12797970 330.00 1.905 1.7 -0.16425625135562 Down 0.106128648791441 CG43156 CG43156 - - - - 37698 674.00 1.295 1.715 0.405256478486258 Up 0.189539030511161 CG9875 CG9875, isoform B - - - - 34882 7260.49 7.95 7.085 -0.166187007253699 Down 0.217507594769515 ck crinkled, isoform D K10359|1|0.0|4189|dme:Dmel_CG7595|myosin VII GO:0044448//cell cortex part;GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0044448//cell cortex part;GO:0042995//cell projection;GO:0015629//actin cytoskeleton GO:0042623//ATPase activity, coupled;GO:0017022//myosin binding;GO:0032559;GO:0042623//ATPase activity, coupled;GO:0017022//myosin binding;GO:0032559 GO:0050954//sensory perception of mechanical stimulus;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0030029//actin filament-based process;GO:0050954//sensory perception of mechanical stimulus;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0030029//actin filament-based process 246397 2795.00 11.69 16.04 0.456399211923264 Up 0.507693831726324 sprt sprite - GO:0044459//plasma membrane part;GO:0031410//cytoplasmic vesicle GO:0005488//binding;GO:0003824//catalytic activity GO:0002164//larval development 317904 992.00 3.7 4.165 0.170791224849236 Up 0.164278166688681 CG32192 CG32192, isoform C - - - - 8673957 1558.00 1.785 1.89 0.0824621601919727 Up 0.0690133403777572 Mst36Fb Male-specific transcript 36Fb - - - - 19835490 857.00 0.145 0.065 -1.15754127698648 Down 0.0982366926429798 - CG45063 - - - - 14462823 706.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 317917 730.00 10.32 5.635 -0.872955455251033 Down 0.577697794214767 CG32212 CG32212 - - - - 33199 1775.21 1.07 1.395 0.382654325428041 Up 0.163221503103949 CG11592 amnionless ortholog, isoform B - - - - 12797865 613.00 0.33 0.15 -1.13750352374993 Down 0.145126139215427 19835351 440.00 0.49 0.36 -0.444784842672896 Down 0.106855105005944 34639 5159.00 8.115 13.88 0.774344568030289 Up 0.591698586712455 CG17211 CG17211 K04657|1|2e-06|55.5|dvi:Dvir_GJ15988|chordin - - - 38592 635.00 0.695 1.28 0.881058927276492 Up 0.258882578259147 CG12027 CG12027 K02131|1|2e-13|75.1|aag:AaeL_AAEL002813|F-type H+-transporting ATPase subunit 6 [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006810//transport;GO:0006754//ATP biosynthetic process 41722 740.00 3.915 3.14 -0.318247748399414 Down 0.247556465460309 CG14356 CG14356 - - - - 42189 1237.00 6.805 4.855 -0.487123866084802 Down 0.405593712851671 CG12320 CG12320 K13205|1|0.0|769|dme:Dmel_CG12320|A1 cistron-splicing factor AAR2 - - - 34785 5818.00 15.48 13.92 -0.153246260295682 Down 0.25937788931449 sec71 Sec71 ortholog K12495|1|2e-35|152|phu:Phum_PHUM029790|IQ motif and SEC7 domain-containing protein GO:0043231//intracellular membrane-bounded organelle GO:0005083//small GTPase regulator activity GO:0048193//Golgi vesicle transport;GO:0032011//ARF protein signal transduction 34426 776.00 13.095 14.595 0.156458151151672 Up 0.263505481442346 SmB small ribonucleoprotein particle protein SmB K11086|1|1e-55|216|dme:Dmel_CG5352|small nuclear ribonucleoprotein B and B' GO:0005681//spliceosomal complex - GO:0000278//mitotic cell cycle;GO:0000377 42888 1960.00 13.265 13.155 -0.0120134270628065 Down 0.0555739004094571 CG5706 CG5706 K01890|1|0.0|1142|dme:Dmel_CG5706|phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] GO:0043234//protein complex;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 43300 6673.88 10.67 13.75 0.365871442474959 Up 0.443204332320697 side sidestep, isoform D K06491|1|8e-19|96.3|mmu:17967|neural cell adhesion molecule GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0007411//axon guidance;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0006357//regulation of transcription from RNA polymerase II promoter 40618 1290.00 0.155 0.355 1.19555080911781 Up 0.153645489367323 CG12590 CG12590 - - - - 317909 470.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 CG32198 CG32198 - - - - 41786 1044.80 162.605 96.895 -0.746877493683245 Down 0.698916919825651 smp-30 senescence marker protein-30, isoform D - - - - 5740321 214.00 142.805 0.28 -8.99440395050676 Down 0.985900145291243 43145 2284.00 1.44 2.705 0.909559782384503 Up 0.37987055871087 CG14540 CG14540 - - - - 41591 1931.59 42.625 41.915 -0.0242332047001778 Down 0.0862171443666623 Paip2 polyA-binding protein interacting protein 2, isoform B - - - - 35759 1476.07 22.095 16.375 -0.43222502444483 Down 0.526152423722097 CSN4 COP9 complex homolog subunit 4, isoform B K12178|1|0.0|789|dme:Dmel_CG8725|COP9 signalosome complex subunit 4 GO:0043234//protein complex;GO:0043234//protein complex GO:0008641//small protein activating enzyme activity;GO:0043565//sequence-specific DNA binding;GO:0008641//small protein activating enzyme activity;GO:0043565//sequence-specific DNA binding GO:0001745//compound eye morphogenesis;GO:0031647//regulation of protein stability;GO:0031330;GO:0070646//protein modification by small protein removal;GO:0001745//compound eye morphogenesis;GO:0031647//regulation of protein stability;GO:0031330;GO:0070646//protein modification by small protein removal 35400 3732.65 24.915 25.19 0.0158365480507086 Up 0.0745278034605732 CG8671 CG8671, isoform G - - - - 34361 1184.34 43.31 44.04 0.0241142964968006 Up 0.0864152687887994 CG5708 CG5708, isoform C K09373|1|5e-24|111|dan:Dana_GF13843|LIM homeobox protein 2/9 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0048856//anatomical structure development;GO:0045449;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0048856//anatomical structure development;GO:0045449;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development 117480 2858.00 0.19 0.345 0.860596943334583 Up 0.124719323735306 Gr64b gustatory receptor 64b K08471|1|0.0|823|dme:Dmel_CG32257|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity - 246411 727.00 3.69 5.33 0.53051471669878 Up 0.383998150838727 CG30039 CG30039 - - GO:0003676//nucleic acid binding - 3355139 1631.24 72.1 74.86 0.0541957887717774 Up 0.152753929467706 CG17883 CG17883, isoform D - GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity;GO:0032318//regulation of Ras GTPase activity 19836113 846.00 3.655 3.66 0.00197224233160517 Up 0.0401862369568089 39498 925.00 0.13 1.165 3.16374642651319 Up 0.417183991546691 CG14107 CG14107 - - - - 41148 1652.00 7.45 7.57 0.0230528746362079 Up 0.0611544049663188 CG9386 CG9386 - - GO:0016741 - 42644 646.00 9.375 5.89 -0.670551056440145 Down 0.51621318187822 Pebp1 Phosphatidylethanolamine-binding protein 1 - - - - 19835638 703.00 0.59 1.26 1.09463687413808 Up 0.28985602958658 39149 465.00 0.925 1.36 0.556081380734027 Up 0.201954827631753 Ilp1 Insulin-like peptide 1 - - GO:0005102//receptor binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 39987 1853.00 23.375 19.605 -0.253744723145772 Down 0.400739664509312 MED19 mediator complex subunit 19, isoform B - GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent 33756 1606.00 16.34 9.115 -0.842093422106549 Down 0.619336943600581 Cyp4ac3 Cyp4ac3 K00517|1|0.0|899|dme:Dmel_CG14031| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0009407//toxin catabolic process 31896 3173.83 19.97 23.69 0.246443865796259 Up 0.399914146083741 CG32700 CG32700, isoform B - - - GO:0008152//metabolic process;GO:0008152//metabolic process 32716 1071.00 10.11 10.66 0.0764244408561613 Up 0.140106987187954 CG8675 CG8675 - - - - 35747 4290.00 5.66 5.745 0.0215048398142308 Up 0.0559701492537313 drosha drosha K03685|1|0.0|2489|dme:Dmel_CG8730|ribonuclease III [EC:3.1.26.3] GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0042254//ribosome biogenesis;GO:0016072//rRNA metabolic process 3346167 6132.35 32.76 36.135 0.141461537318618 Up 0.297582882049927 btsz bitesize, isoform J K01104|1|1e-28|130|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00923|2|3e-16|89.4|bfo:BRAFLDRAFT_233446|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first;GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first;GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first;GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first;GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first;GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first;GO:0007043//cell-cell junction assembly;GO:0007164//establishment of tissue polarity;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0008361//regulation of cell size;GO:0051234//establishment of localization;GO:0002009//morphogenesis of an epithelium;GO:0001703//gastrulation with mouth forming first 35322 1989.00 1.57 1.46 -0.10479619001161 Down 0.0744947827235504 phr6-4 (6-4)-photolyase, isoform D K02295|1|0.0|1076|dme:Dmel_CG2488|cryptochrome - GO:0003913//DNA photolyase activity;GO:0003913//DNA photolyase activity GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process 33044 1864.60 14.11 15.28 0.114926555438485 Up 0.206247523444723 CG11710 CG11710, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 37598 1115.84 0.605 0.225 -1.42701014094492 Down 0.226159027869502 CG42565 CG42565, isoform B - - - - 14462554 700.00 0.115 0.2 0.79836613883035 Up 0.0976092986395456 7354380 1117.00 15.78 17.305 0.133091736151989 Up 0.241876898692379 CG42375 CG42375 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0006544//glycine metabolic process 12797977 1185.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 CG43088 CG43088 - - - - 38003 2253.78 72.18 85.52 0.244662709823258 Up 0.454035134064192 Nplp1 Neuropeptide-like precursor 1, isoform C - - GO:0005179//hormone activity;GO:0005179//hormone activity;GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway 36398 1327.36 4.025 6.085 0.596268479711749 Up 0.42910447761194 CG13148 CG13148, isoform D - - - - 32745 3668.00 6.34 6.76 0.0925404061427771 Up 0.130167745344076 IntS2 integrator 2 K13139|1|0.0|2179|dme:Dmel_CG8211|integrator complex subunit 2 - - - 40817 2775.00 1.49 1.325 -0.1693199710116 Down 0.0996896050719852 lab labial, isoform B K09301|1|4e-155|548|dme:Dmel_CG1264|homeobox protein HoxA/B/D1 - - GO:0010468//regulation of gene expression;GO:0007420//brain development;GO:0006350 19835040 751.00 0.11 0.18 0.710493382805015 Up 0.0861180821555937 34789 557.00 2.535 2.975 0.230903921191965 Up 0.168802007660811 CG16888 CG16888 - - - - 19835051 3286.00 2.69 2.805 0.0603945980521684 Up 0.0690463611147801 - pre-mod(mdg4)-B - - - - 35048 1160.92 2.86 4.355 0.606657571820475 Up 0.379573372077665 CG5050 CG5050, isoform B K12478|1|2e-08|60.1|cel:T10G3.5|early endosome antigen 1;K10352|2|1e-07|57.8|isc:IscW_ISCW001340|myosin heavy chain;K04648|3|2e-07|57.0|bfo:BRAFLDRAFT_126882|dynactin 1 - - - 40646 948.00 0.7 0.415 -0.754243585598042 Down 0.173226786421873 CG14668 CG14668 - - - - 19835480 1937.00 0.665 0.4 -0.733354340613827 Down 0.160844010038304 34309 916.73 646.5 688.35 0.090491937435812 Up 0.246004490820235 RpS2 ribosomal protein S2, isoform C K02981|1|3e-121|434|dme:Dmel_CG5920|small subunit ribosomal protein S2e GO:0015935//small ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0010467//gene expression 40606 2401.00 0.175 0.265 0.598637437618233 Up 0.0941091005151235 laf labial associated factor, isoform B - GO:0043231//intracellular membrane-bounded organelle - - 50301 531.00 1.74 2.51 0.528600058102044 Up 0.27143045832783 CG13306 CG13306 - - - - 41698 1110.00 0.04 0.01 -2 Down 0.0694426099590543 Art9 arginine methyltransferase 9 K11434|1|2e-41|170|isc:IscW_ISCW023973|protein arginine N-methyltransferase 1 [EC:2.1.1.-] - - - 42648 812.00 7.38 4.78 -0.626610198079647 Down 0.469191652357681 CG5376 CG5376 K10394|1|2e-07|55.8|dre:100101641|kinesin family member 3/17;K11498|3|2e-06|53.1|xla:394299|centromeric protein E;K10400|4|3e-06|52.4|spu:373236|kinesin family member 15;K06267|5|3e-06|52.4|oaa:100079090|hyaluronan-mediated motility receptor - - - 32564 1454.00 22.055 22.925 0.0558159733901993 Up 0.144828952582222 CG8931 CG8931 - GO:0031224//intrinsic to membrane - GO:0006810//transport 38652 3761.83 11.89 12.95 0.12320338282826 Up 0.207436269977546 Bre1 Bre1, isoform B K10696|1|0.0|1816|dme:Dmel_CG10542|E3 ubiquitin-protein ligase BRE1 [EC:6.3.2.19] - GO:0046914//transition metal ion binding GO:0006909//phagocytosis;GO:0006464//cellular protein modification process;GO:0007399//nervous system development 40014 1699.00 1.72 1.325 -0.376416205251536 Down 0.181052701096288 grim grim - GO:0043231//intracellular membrane-bounded organelle - GO:0006412//translation;GO:0002165//instar larval or pupal development;GO:0032446//protein modification by small protein conjugation;GO:0010259//multicellular organismal aging;GO:0006508//proteolysis;GO:0008629;GO:0006582//melanin metabolic process;GO:0009792//embryo development ending in birth or egg hatching 33473 5445.93 252.42 269.725 0.0956630228999175 Up 0.262580900805706 Syt1 synaptotagmin 1, isoform I K01104|1|3e-91|337|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|4|7e-28|126|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10];K03008|5|3e-14|81.3|gga:417513|DNA-directed RNA polymerase II subunit J GO:0030672//synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding GO:0007626//locomotory behavior;GO:0007269//neurotransmitter secretion;GO:0006887//exocytosis;GO:0044087;GO:0006897//endocytosis;GO:0007626//locomotory behavior;GO:0007269//neurotransmitter secretion;GO:0006887//exocytosis;GO:0044087;GO:0006897//endocytosis;GO:0007626//locomotory behavior;GO:0007269//neurotransmitter secretion;GO:0006887//exocytosis;GO:0044087;GO:0006897//endocytosis;GO:0007626//locomotory behavior;GO:0007269//neurotransmitter secretion;GO:0006887//exocytosis;GO:0044087;GO:0006897//endocytosis 37541 1280.00 0.54 1.465 1.43986935225878 Up 0.351340641923128 CG11291 CG11291 K01101|1|3e-161|567|dme:Dmel_CG11291|4-nitrophenyl phosphatase [EC:3.1.3.41] - GO:0003824//catalytic activity - 37454 822.00 0.05 0.06 0.263034405833794 Up 0.0467903843613789 CG30283 CG30283 K01362|1|9e-29|127|dme:Dmel_CG4920| [EC:3.4.21.-];K09632|3|5e-26|117|dre:447843|chymotrypsin-like protease [EC:3.4.21.-];K03993|4|5e-26|117|gga:407089|mannan-binding lectin serine protease 2 [EC:3.4.21.104];K01310|5|1e-24|113|xtr:496968|chymotrypsin [EC:3.4.21.1] - - - 42717 3197.00 0.24 0.285 0.247927513443586 Up 0.0674943864747061 lmd lame duck, isoform C K09232|1|9e-73|275|spu:593964|zinc finger protein GLIS1/3 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0000768//syncytium formation by plasma membrane fusion;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-dependent 42881 1591.16 3.015 5.5 0.867273616511937 Up 0.488310659093911 cav caravaggio, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0000781//chromosome, telomeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000781//chromosome, telomeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000781//chromosome, telomeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000781//chromosome, telomeric region GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding GO:0000723//telomere maintenance;GO:0000723//telomere maintenance;GO:0000723//telomere maintenance;GO:0000723//telomere maintenance 32703 11802.78 19.42 25.645 0.401134370558125 Up 0.522421080438515 baz bazooka, isoform D K04237|1|0.0|2046|der:Dere_GG19100|partitioning defective protein 3 GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0005913//cell-cell adherens junction;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0005913//cell-cell adherens junction GO:0005543//phospholipid binding;GO:0005543//phospholipid binding GO:0000278//mitotic cell cycle;GO:0010004//gastrulation involving germ band extension;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0016337//cell-cell adhesion;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0007399//nervous system development;GO:0000278//mitotic cell cycle;GO:0010004//gastrulation involving germ band extension;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0016337//cell-cell adhesion;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0007399//nervous system development 39480 613.00 698.755 642.085 -0.122022405588565 Down 0.304484216087703 RpS12 ribosomal protein S12 K02951|1|6e-67|253|dya:Dyak_GE21945|small subunit ribosomal protein S12e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 49815 1473.00 0.16 0.29 0.857980995127572 Up 0.116629243164707 Cht4 chitinase 4 K01183|1|0.0|874|dme:Dmel_CG3986|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding GO:0006032//chitin catabolic process 37615 1017.00 0.58 0.88 0.601450623509725 Up 0.168471800290582 CG13527 CG13527, isoform B K01362|1|9e-31|134|dme:Dmel_CG3795| [EC:3.4.21.-];K01312|2|7e-23|107|dpo:Dpse_GA11598|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39574 1079.00 0.41 0.51 0.314873337353412 Up 0.0904107779685643 CG7924 CG7924 - - - - 37078 2146.00 4.72 5.765 0.288533748289931 Up 0.277176066569806 Nup75 nucleoporin 75kD - - - - 36035 1128.00 14.915 13.765 -0.115759367739651 Down 0.21328094043059 CG1418 CG1418 - - - - 19835661 459.00 0.275 0.01 -4.78135971352466 Down 0.252509576013737 19836097 900.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 317912 1149.00 3.365 2.76 -0.285938237832148 Down 0.213941355171047 Spn75F serpin 75F K13963|1|5e-21|102|mdo:100017160|serpin B - GO:0004866//endopeptidase inhibitor activity - 31109 457.00 6.72 3.685 -0.866796613683691 Down 0.519845462950733 CG14795 CG14795 - - - - 32993 2896.00 0.315 0.585 0.893084796083488 Up 0.172368247259279 CG12702 CG12702, isoform C K10352|1|3e-10|67.8|xla:100158453|myosin heavy chain;K08282|3|3e-09|64.7|mmu:12704|non-specific serine/threonine protein kinase [EC:2.7.11.1] - - - 34539 2949.85 8.3 10.265 0.306550385874315 Up 0.365836745476159 CG16854 CG16854, isoform D - - - - 31872 1702.30 19.735 20.74 0.0716593749201224 Up 0.160282657508916 Dsor1 downstream of raf1, isoform B K04368|1|0.0|740|dme:Dmel_CG15793|mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] - GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0007243//intracellular protein kinase cascade;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002376//immune system process;GO:0000578//embryonic axis specification;GO:0008063//Toll signaling pathway;GO:0006464//cellular protein modification process 42340 3745.76 19.89 17.805 -0.159760840470681 Down 0.288997490423986 CG16718 subdued, isoform F K13982|1|2e-32|142|dgr:Dgri_GH10918|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13];K05169|2|2e-20|102|ptr:743996|single Ig IL-1R-related molecule - - - 31283 1047.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG3598 CG3598 - - - - 42696 986.00 13.02 16.245 0.319266295163848 Up 0.429830933826443 HP1c heterochromatin protein 1c K11586|1|7e-137|486|dme:Dmel_CG6990|chromobox protein 3 GO:0044427//chromosomal part;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0005488//binding GO:0006325//chromatin organization 59175 956.00 0.125 0.225 0.84799690655495 Up 0.10276053361511 CG18814 CG18814 K00001|1|4e-35|148|dwi:Dwil_GK18290|alcohol dehydrogenase [EC:1.1.1.1] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0044281//small molecule metabolic process 39716 1516.00 20.905 16.37 -0.352793721569984 Down 0.475531633866068 comm2 comm2 - - - - 37418 1630.00 16.115 11.225 -0.521688743431036 Down 0.534374587240787 Lapsyn Leucine-rich repeat activity-regulated protein at synapses K07523|1|1e-19|98.2|ecb:100049944|netrin-G1 ligand - - - 36047 399.00 34.73 40.805 0.232563531507119 Up 0.416028265750892 Def defensin - GO:0044421//extracellular region part - GO:0002815 39103 8463.00 9.735 11.165 0.197730367102179 Up 0.281303658697662 Jarid2 Jumonji, AT rich interactive domain 2 K11446|1|2e-32|142|nvi:100120294|histone demethylase JARID1 [EC:1.14.11.-] GO:0044464//cell part GO:0003676//nucleic acid binding - 42572 941.00 18.12 17.595 -0.0424174412965705 Down 0.109463743230749 lsn larsen K12188|1|7e-139|493|dme:Dmel_CG6637|ESCRT-II complex subunit VPS22 - - GO:0010796//regulation of multivesicular body size;GO:0048610//cellular process involved in reproduction 12798343 242.00 129.705 93.17 -0.477296696714412 Down 0.626634526482631 CG43351 CG43351 - - - - 19836192 500.17 2.415 2.075 -0.218911852601486 Down 0.147074362699775 39208 1022.00 54.195 47.83 -0.180243964167294 Down 0.368148197067759 CG14153 CG14153 - - - - 41496 952.00 0.455 0.515 0.178705886984522 Up 0.0682868841632545 CG10041 CG10041 K01324|1|1e-18|94.0|gga:422723|plasma kallikrein [EC:3.4.21.34];K08649|3|2e-18|92.8|mmu:16904|granzyme M [EC:3.4.21.-] - - - 37215 1092.00 10.885 12.295 0.175730327407876 Up 0.269878483687756 mip40 Myb-interacting protein 40 - - - - 14462468 897.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 38978 9455.87 44.465 52.275 0.233450971166577 Up 0.426892088231409 rhea rhea, isoform I K06271|1|0.0|5125|dme:Dmel_CG6831|talin GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0005198//structural molecule activity GO:0006909//phagocytosis;GO:0007010//cytoskeleton organization;GO:0010669//epithelial structure maintenance;GO:0032502//developmental process;GO:0032583 5740518 1072.00 0.04 0.125 1.64385618977472 Up 0.101736890767402 CG40968 CG40968 K02355|1|7e-45|127|dsi:Dsim_GD20968|elongation factor EF-G [EC:3.6.5.3] - GO:0005488//binding - 42822 617.00 83.185 75.885 -0.132508663781189 Down 0.305408796724343 TfIIA-S Transcription-factor-IIA-S K03123|1|1e-55|215|dme:Dmel_CG5163|transcription initiation factor TFIIA small subunit GO:0005667//transcription factor complex GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 319048 1341.37 18.395 18.585 0.0148250118887833 Up 0.0605600316999075 CG31961 CG31961, isoform B - - - - 37682 1302.00 1.41 1.73 0.295076875237931 Up 0.155461629903579 CG3092 CG3092 - - - - 35040 1069.00 1.875 1.925 0.0379678501990204 Up 0.0540219257693832 CG6380 CG6380, isoform B - - GO:0019212//phosphatase inhibitor activity GO:0007165//signal transduction;GO:0010921//regulation of phosphatase activity 41575 2229.00 10.7 11.88 0.150924039512256 Up 0.236758684453837 beat-Vc beat-Vc - - - - 5740152 1813.00 0.265 0.18 -0.557995453120887 Down 0.0934156650376436 CG34342 CG34342, isoform E K13356|1|6e-50|198|ame:551233|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 31639 6246.60 4.725 8.685 0.878211519601958 Up 0.55768722757892 CG14431 CG14431, isoform C - - - - 38858 721.00 39.775 72.52 0.866516994525748 Up 0.700402852991679 PGRP-SD PGRP-SD K01446|1|3e-105|380|dme:Dmel_CG7496|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0042742//defense response to bacterium;GO:0002376//immune system process 43166 773.00 2.31 1.865 -0.30871722116082 Down 0.186071853123762 Sld5 Sld5 K10735|1|6e-121|432|dse:Dsec_GM10199|GINS complex subunit 4 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0007090//regulation of S phase of mitotic cell cycle 14462616 903.00 0.05 0.065 0.37851162325373 Up 0.0544181746136574 CG43677 CG43677 - - - - 31368 1716.00 0.025 0.08 1.67807190511264 Up 0.0883304715361247 Muc4B mucin 4B, isoform C - - - - 45432 2953.00 0.105 0.175 0.736965594166206 Up 0.0868115176330736 can cannonball K03130|1|0.0|1651|dme:Dmel_CG6577|transcription initiation factor TFIID subunit D4 GO:0005667//transcription factor complex GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0010468//regulation of gene expression;GO:0007281//germ cell development;GO:0007140//male meiosis 47769 1768.45 38.46 28.59 -0.427848142708799 Down 0.565711266675472 Dip-C dipeptidase C, isoform B K01271|1|0.0|1006|dme:Dmel_CG5663|X-Pro dipeptidase [EC:3.4.13.9] - GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 246610 363.87 9.665 14.045 0.539214986915163 Up 0.526251485933166 CG30430 CG30430, isoform B - - - - 39217 4953.39 30.995 29.935 -0.050202233742705 Down 0.138224805177652 tna tonalli, isoform D K04706|1|2e-16|89.4|smm:Smp_172130|protein inhibitor of activated STAT - - - 44002 1271.00 6.545 5.05 -0.374109804306084 Down 0.345297847047946 Sras severas K08658|1|1e-165|582|dme:Dmel_CG4852|prenyl protein peptidase [EC:3.4.22.-] GO:0031227//intrinsic to endoplasmic reticulum membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33226 1118.28 68.105 60.525 -0.170229544870778 Down 0.361808215559371 lwr lesswright, isoform D K10577|1|1e-91|337|dvi:Dvir_GJ19711|ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19] GO:0000777//condensed chromosome kinetochore;GO:0000794//condensed nuclear chromosome;GO:0000777//condensed chromosome kinetochore;GO:0000794//condensed nuclear chromosome GO:0019787//small conjugating protein ligase activity;GO:0005488//binding;GO:0019787//small conjugating protein ligase activity;GO:0005488//binding GO:0002683//negative regulation of immune system process;GO:0007143//female meiosis;GO:0006955//immune response;GO:0006605//protein targeting;GO:0035171//lamellocyte differentiation;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0008592//regulation of Toll signaling pathway;GO:0060255;GO:0002683//negative regulation of immune system process;GO:0007143//female meiosis;GO:0006955//immune response;GO:0006605//protein targeting;GO:0035171//lamellocyte differentiation;GO:0000578//embryonic axis specification;GO:0006464//cellular protein modification process;GO:0008592//regulation of Toll signaling pathway;GO:0060255 41013 1801.01 4.965 4.68 -0.0852851879449695 Down 0.109232598071589 pch2 pch2, isoform B K13525|1|4e-14|79.7|bmy:Bm1_55480|transitional endoplasmic reticulum ATPase - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 43026 2939.00 16.35 9.775 -0.74212202819073 Down 0.602034077400608 Cad96Ca cadherin 96Ca K08252|1|0.0|1310|dme:Dmel_CG10244|receptor protein-tyrosine kinase [EC:2.7.10.1];K05094|2|2e-78|294|nve:NEMVE_v1g31143|fibroblast growth factor receptor 3 [EC:2.7.10.1];K05126|3|6e-78|292|tca:657748|proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1];K04362|4|2e-77|291|mdo:100029852|fibroblast growth factor receptor 1 [EC:2.7.10.1] GO:0016021//integral to membrane GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0016337//cell-cell adhesion;GO:0006464//cellular protein modification process 117487 1185.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 Gr36b gustatory receptor 36b K08471|1|0.0|738|dme:Dmel_CG31744|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 34833 4826.00 0.27 0.55 1.02647221136119 Up 0.182208426892088 ms(2)34Fe male sterile (2) 34Fe - - - - 44251 998.57 780.915 717.845 -0.121493159238651 Down 0.304847444194954 RpL8 ribosomal protein L8, isoform B K02938|1|2e-138|492|dya:Dyak_GE20324|large subunit ribosomal protein L8e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 31952 1358.00 0.035 0.035 0 - 0.0382380134724607 CG2962 CG2962 K05746|1|7e-09|62.0|bta:513095|enabled - GO:0005488//binding - 36552 1146.00 10.775 11.145 0.048708747283292 Up 0.105270109628847 CG8067 CG8067, isoform B - - GO:0016741 - 326214 951.00 8.03 8.335 0.0537822114691025 Up 0.098864086646414 vito viriato - - - - 33435 3100.74 16.58 16.705 0.0108359758392198 Up 0.0563994188350284 oaf out at first, isoform D - - - GO:0048731;GO:0007143//female meiosis;GO:0048731;GO:0007143//female meiosis;GO:0048731;GO:0007143//female meiosis;GO:0048731;GO:0007143//female meiosis 43343 1097.00 2.805 4.445 0.664182648220977 Up 0.397734777440232 CG5017 milkah K11279|1|2e-128|458|dme:Dmel_CG5017|nucleosome assembly protein 1-like 1 GO:0043231//intracellular membrane-bounded organelle - GO:0034728//nucleosome organization 44126 3704.00 5.005 4.5 -0.153445067618957 Down 0.164410249636772 AlstR allatostatin A receptor 1, isoform D K04233|1|0.0|642|dsi:Dsim_GD16646|galanin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 5740576 144.00 0.01 0.455 5.5077946401987 Up 0.339420155857879 31607 2853.67 64.15 72.2 0.170549571797489 Up 0.363492273147537 Pink1 PTEN-induced putative kinase 1, isoform I K05688|1|4e-64|246|tgu:100229816|PTEN induced putative kinase 1 [EC:2.7.11.1] - - - 43725 3136.68 15.74 16.24 0.0451160916776899 Up 0.116266015057456 Med medea, isoform C K04501|1|1e-152|540|dme:Dmel_CG1775|SMAD, mothers against DPP 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity GO:0007411//axon guidance;GO:0006351//transcription, DNA-dependent;GO:0045704;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010468//regulation of gene expression;GO:0007478//leg disc morphogenesis;GO:0019827//stem cell maintenance;GO:0009798//axis specification;GO:0007281//germ cell development;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007472//wing disc morphogenesis;GO:0007411//axon guidance;GO:0006351//transcription, DNA-dependent;GO:0045704;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010468//regulation of gene expression;GO:0007478//leg disc morphogenesis;GO:0019827//stem cell maintenance;GO:0009798//axis specification;GO:0007281//germ cell development;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007472//wing disc morphogenesis 42764 5771.95 6.42 9.14 0.509620867935767 Up 0.458625016510369 CG4393 CG4393, isoform D K10380|1|2e-23|112|smm:Smp_154020|ankyrin - - - 40095 1044.61 34.825 29.405 -0.244061862326684 Down 0.41797648923524 Max Max, isoform D K04453|1|5e-70|264|dme:Dmel_CG9648|Max protein GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 19835135 801.00 0.15 0.135 -0.15200309344505 Down 0.045238409721305 37980 2116.00 13.09 23.06 0.816927415706531 Up 0.643409060890239 Ance-5 Ance-5 K01283|1|0.0|1291|dme:Dmel_CG10142|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0044464//cell part GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 36340 2087.43 60.47 45.88 -0.398354187635727 Down 0.570103024699511 CG8839 CG8839, isoform E K01426|1|3e-82|306|dpo:Dpse_GA20671|amidase [EC:3.5.1.4];K01175|3|3e-27|123|mdo:100023944| [EC:3.1.-.-] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds - 36321 709.33 843.9 809.445 -0.0601389974573623 Down 0.185180293224145 RpS11 ribosomal protein S11, isoform C K02949|1|2e-79|295|dya:Dyak_GE13464|small subunit ribosomal protein S11e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 41563 1651.00 1.3 1.415 0.122290429803428 Up 0.0806696605468234 Cyp313a4 Cyp313a4 K00517|1|0.0|984|dme:Dmel_CG6802| [EC:1.14.-.-] - - - 14462758 273.00 0.01 0.415 5.37503943134692 Up 0.323239994716682 10178916 578.00 0.935 0.33 -1.50250034052918 Down 0.29124290054154 CG42822 CG42822 - - - - 38218 3816.78 42.64 45.145 0.0823587738692624 Up 0.201591599524501 drpr draper, isoform F K06252|1|2e-69|265|hsa:7148|tenascin GO:0044425//membrane part GO:0005488//binding;GO:0005488//binding GO:0006909//phagocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007626//locomotory behavior;GO:0006909//phagocytosis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007626//locomotory behavior 32156 1095.20 299.925 91.945 -1.70575875422741 Down 0.779388455950337 Sclp sclp, isoform C K10641|1|1e-09|63.2|mdo:100011228|E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19];K01090|5|5e-09|61.2|mmu:244650|protein phosphatase [EC:3.1.3.16] - GO:0005488//binding;GO:0005488//binding - 38937 2851.72 21.155 20.42 -0.0510158194785488 Down 0.128087438911637 CG7185 CG7185, isoform B K13911|1|2e-25|118|spu:577326|basic salivary proline-rich protein 1/2 - - GO:0000380//alternative mRNA splicing, via spliceosome 53516 612.00 0.595 0.01 -5.89481776330794 Down 0.392253335094439 lectin-33A lectin-33A K06560|1|2e-11|68.9|hmg:100206932|mannose receptor, C type;K06563|4|9e-10|63.2|rno:363856|CD209 antigen - - - 3772412 2227.00 0.525 0.47 -0.159656665988485 Down 0.0640932505613525 CG4970 CG4970 K10392|1|1e-07|58.5|mcc:695167|kinesin family member 1/13/14;K10396|3|5e-07|56.6|dre:565563|kinesin family member 5;K10352|5|1e-06|55.5|cel:F52B10.1|myosin heavy chain - - - 33426 977.00 0.635 0.84 0.403632736006594 Up 0.128252542596751 CG3557 CG3557, isoform C - - - - 14462402 2749.00 0.49 0.365 -0.424885285235191 Down 0.102628450667019 39597 1657.00 6.045 3.14 -0.944977780357497 Down 0.518788799366002 CG4914 CG4914 K01312|1|8e-45|181|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|2|5e-44|179|mmu:16621|plasma kallikrein [EC:3.4.21.34];K01320|3|9e-43|174|dre:100038778|coagulation factor VII [EC:3.4.21.21];K09637|4|3e-42|173|gga:418046|transmembrane protease, serine 6 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42594 1163.00 4.535 2.545 -0.833436894452827 Down 0.447695152555805 BG4 Fas-associated death domain ortholog - GO:0044424//intracellular part GO:0032813//tumor necrosis factor receptor superfamily binding GO:0012501//programmed cell death;GO:0023060;GO:0002780;GO:0003006//developmental process involved in reproduction 4379860 1491.91 14.14 14.065 -0.00767256749469903 Down 0.0513802668075551 muted muted ortholog, isoform B - - - - 36300 1186.00 1.03 1.045 0.0208586048976644 Up 0.0413749834896315 CG13178 CG13178 - - - - 246398 810.00 0.04 0.31 2.95419631038688 Up 0.209846783780214 CG30025 CG30025 K01312|1|5e-107|386|dme:Dmel_CG30031|trypsin [EC:3.4.21.4] GO:0005576//extracellular region GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 36632 2777.51 30.915 19.45 -0.668536850386858 Down 0.629936600184916 mspo M-spondin, isoform B K03995|1|8e-08|59.7|cin:100183313|complement component 6 - - - 19835804 475.00 155.59 259.94 0.740429316053729 Up 0.702450138687095 43160 982.00 0.825 0.465 -0.827163403137784 Down 0.198355567296262 E(spl)m7-HLH enhancer of split m7, helix-loop-helix K09090|1|3e-87|321|dme:Dmel_CG8361|hairy and enhancer of split, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-dependent;GO:0009887//organ morphogenesis;GO:0007626//locomotory behavior;GO:0048812//neuron projection morphogenesis;GO:0009605//response to external stimulus 53507 1671.00 37.345 6.345 -2.55722302904092 Down 0.781898031964073 Ugt86Dd Ugt86Dd K00699|1|0.0|883|dme:Dmel_CG6633|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 34155 1012.00 22.45 25.855 0.20372785985488 Up 0.357581561220446 CG17294 CG17294 K01101|1|1e-144|512|dme:Dmel_CG17294|4-nitrophenyl phosphatase [EC:3.1.3.41];K11725|2|5e-43|174|bfo:BRAFLDRAFT_233674|phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-] - GO:0003824//catalytic activity - 34508 1082.00 0.145 0.36 1.31194400631474 Up 0.160381719719984 CG14070 CG14070, isoform B - - - - 40721 6816.00 27.74 25.915 -0.0981803939389036 Down 0.220314357416458 CG11000 CG11000, isoform C - GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 40945 3152.75 38.76 50.585 0.38414107436777 Up 0.553097345132743 CG2698 CG2698, isoform I - - - - 14462806 546.00 0.01 0.09 3.16992500144231 Up 0.120756835292564 50250 2117.63 214.905 245.235 0.190465846482113 Up 0.411735569937921 CG14767 CG14767, isoform C K12387|1|0.0|702|dsi:Dsim_GD10140|lysosomal-associated transmembrane protein GO:0005764//lysosome;GO:0031224//intrinsic to membrane;GO:0005764//lysosome;GO:0031224//intrinsic to membrane;GO:0005764//lysosome;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0005488//binding;GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0005488//binding;GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 34296 1616.00 2.445 2.385 -0.0358451989467225 Down 0.0559371285167085 CG4017 CG4017 K01290|1|6e-74|278|dvi:Dvir_GJ16227|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 41121 1069.00 20.835 16.6 -0.327825858468262 Down 0.460738343679831 CG8132 CG8132 K13566|1|1e-162|572|dme:Dmel_CG8132|omega-amidase [EC:3.5.1.3] - GO:0016787//hydrolase activity GO:0008152//metabolic process 41815 756.00 1.175 0.12 -3.29155444584384 Down 0.422863558314622 CG6974 CG6974 K13046|1|1e-24|113|ame:410386|tolkin [EC:3.4.24.-];K08076|2|3e-24|111|cel:F57C12.1|astacin [EC:3.4.24.21];K01395|5|8e-23|107|mmu:17287|meprin A, alpha [EC:3.4.24.18] - - - 39873 4158.00 14.265 16.275 0.190177796471278 Up 0.308710870426628 Nrt neurotactin, isoform C K03927|1|5e-34|147|hmg:100213105|carboxylesterase type B [EC:3.1.1.1];K01044|3|1e-26|122|dme:Dmel_CG2505|carboxylesterase [EC:3.1.1.1] GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane;GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane - GO:0006935//chemotaxis;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0007409//axonogenesis 12798216 364.00 13.065 19.635 0.587720473346376 Up 0.578061022322018 33560 2028.00 30.645 24.495 -0.323164413171533 Down 0.486296394135517 Snx1 sorting nexin 1, isoform B - - GO:0005543//phospholipid binding GO:0009987//cellular process 31918 527.57 46.535 35.78 -0.37916281985709 Down 0.549068815215956 CG32695 CG32695, isoform C - - - - 43981 3063.80 131.64 166.715 0.340785983499564 Up 0.559767534011359 DIP1 DISCO interacting protein 1, isoform I - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding - 34873 730.00 21.95 20.85 -0.0741735560906947 Down 0.163650772685246 dyn-p25 dynactin-subunit-p25 K10427|1|1e-106|385|dsi:Dsim_GD23985|dynactin 5 GO:0005875//microtubule associated complex GO:0003824//catalytic activity GO:0007017//microtubule-based process 32723 3102.00 1.895 1.665 -0.186675671099829 Down 0.116100911372342 B-H2 BarH2, isoform B K09360|1|7e-50|199|dme:Dmel_CG5529|BarH-like GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0010468//regulation of gene expression;GO:0001745//compound eye morphogenesis;GO:0048753//pigment granule organization;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0006351//transcription, DNA-dependent;GO:0007560//imaginal disc morphogenesis 39991 2577.48 9.52 6.95 -0.453948595697074 Down 0.439274864614978 CG7408 CG7408, isoform D K01135|1|2e-129|464|dme:Dmel_CG7402|arylsulfatase B [EC:3.1.6.12] - GO:0016788//hydrolase activity, acting on ester bonds;GO:0016788//hydrolase activity, acting on ester bonds;GO:0016788//hydrolase activity, acting on ester bonds - 32149 827.00 61.255 49.765 -0.299696166808748 Down 0.503995509179765 SelG selenoprotein G - GO:0042598;GO:0043231//intracellular membrane-bounded organelle - GO:0010259//multicellular organismal aging;GO:0019725//cellular homeostasis 36724 795.64 1.33 1.115 -0.254382535580885 Down 0.11666226390173 CG12963 CG12963, isoform N - - - - 19835651 402.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 39962 6029.41 14.225 11.01 -0.369614183629575 Down 0.447860256240919 Eip74EF Ecdysone-induced protein 74EF, isoform E K09428|1|0.0|887|dme:Dmel_CG32180|E74-like factor 1/2/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0044248//cellular catabolic process;GO:0050789//regulation of biological process;GO:0048102//autophagic cell death;GO:0032502//developmental process;GO:0044248//cellular catabolic process;GO:0050789//regulation of biological process;GO:0048102//autophagic cell death;GO:0032502//developmental process;GO:0044248//cellular catabolic process;GO:0050789//regulation of biological process;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0032502//developmental process;GO:0044248//cellular catabolic process;GO:0050789//regulation of biological process;GO:0006351//transcription, DNA-dependent;GO:0048102//autophagic cell death;GO:0032502//developmental process 36628 1111.00 11.875 17.07 0.523535544922065 Up 0.541176859067494 CG12861 CG12861 - - - - 31048 462.00 0.275 0.32 0.21864028647534 Up 0.0618148197067759 TfIIA-S-2 TfIIA-S-2 K03123|1|4e-57|219|dme:Dmel_CG11639|transcription initiation factor TFIIA small subunit - - - 40624 1023.60 45.035 41.225 -0.127527167777896 Down 0.289426760005283 CG1115 vacuolar protein sorting 37B, isoform C K12185|1|2e-78|292|dme:Dmel_CG1115|ESCRT-I complex subunit VPS37 - - - 246646 728.00 1.465 1.395 -0.0706355425930604 Down 0.0606590939109761 CG30487 CG30487 - - - - 38864 1461.00 176.215 117.76 -0.581487159921791 Down 0.664014000792498 CG12262 CG12262 K00249|1|0.0|825|dsi:Dsim_GD14030|acyl-CoA dehydrogenase [EC:1.3.99.3] GO:0031980;GO:0015630//microtubule cytoskeleton GO:0030554//adenyl nucleotide binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors GO:0009062//fatty acid catabolic process 42069 1012.00 0.27 0.6 1.15200309344505 Up 0.201822744683661 CG17475 CG17475, isoform B K11997|1|7e-37|154|ame:409206|tripartite motif-containing protein 2/3;K01312|2|2e-31|136|bfo:BRAFLDRAFT_88359|trypsin [EC:3.4.21.4];K09633|4|1e-28|127|xla:779110|transmembrane protease, serine 2 [EC:3.4.21.-];K01362|5|8e-28|124|mcc:698983| [EC:3.4.21.-] - - - 36818 762.00 0.69 1.32 0.935869662580284 Up 0.273807951393475 CG30099 CG30099 - - - - 31319 774.00 18.455 20.96 0.183626979291842 Up 0.319673755118214 CG14270 CG14270 - - - - 37517 4560.96 38.185 41.01 0.102969719946005 Up 0.236494518557654 synj synaptojanin, isoform C K01099|1|0.0|2122|dme:Dmel_CG6562|phosphatidylinositol-bisphosphatase [EC:3.1.3.36] GO:0033267//axon part;GO:0012505//endomembrane system;GO:0033267//axon part;GO:0012505//endomembrane system GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0046030//inositol trisphosphate phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0007269//neurotransmitter secretion;GO:0006897//endocytosis;GO:0006796//phosphate-containing compound metabolic process;GO:0007269//neurotransmitter secretion;GO:0006897//endocytosis 36516 506.00 1.94 0.455 -2.09211820198843 Down 0.455422005019152 CG12464 CG12464 - - - - 40318 866.00 0.41 0.655 0.675870996919366 Up 0.150772685246335 CG10587 CG10587, isoform D K01312|1|5e-26|77.4|dpo:Dpse_GA21879|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 32310 1320.00 0.065 0.045 -0.53051471669878 Down 0.0549134856690001 CG11816 CG11816, isoform D - - - - 19836126 624.00 0.07 0.29 2.05062607306997 Up 0.175769383172632 42029 2033.99 24.315 19.605 -0.310624949722108 Down 0.458591995773346 Cctgamma cctgamma, isoform D K09495|1|0.0|1028|dme:Dmel_CG8977|T-complex protein 1 subunit gamma GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process 50467 662.99 77.28 78.485 0.0223218592772876 Up 0.0889578655395588 CG17325 CG17325, isoform C - - - - 37273 2010.00 0.585 0.945 0.691877704637668 Up 0.189968300092458 CG13872 CG13872 - - - - 42761 887.35 872.1 764.54 -0.189901588212888 Down 0.418504821027605 RpS3 ribosomal protein S3, isoform B K02985|1|5e-137|486|dme:Dmel_CG6779|small subunit ribosomal protein S3e GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0015935//small ribosomal subunit GO:0016835//carbon-oxygen lyase activity;GO:0003676//nucleic acid binding;GO:0000702//oxidized base lesion DNA N-glycosylase activity;GO:0005198//structural molecule activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process 39302 3047.86 23.06 20.715 -0.154716692672565 Down 0.289327697794215 CG6091 CG6091, isoform G K12655|1|9e-98|358|cqu:CpipJ_CPIJ002852|OTU domain-containing protein 5 [EC:3.1.2.15] - - - 40374 2347.00 1.11 1.635 0.558730959147976 Up 0.223748514066834 croc crocodile K09396|1|0.0|669|dme:Dmel_CG5069|forkhead box protein C GO:0043231//intracellular membrane-bounded organelle GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0048856//anatomical structure development;GO:0006355//regulation of transcription, DNA-dependent;GO:0007379//segment specification 318681 2198.00 23.67 18.355 -0.366886591635067 Down 0.4988442742042 CG31321 CG31321 - - - GO:0006810//transport 37666 388.00 0.01 0.13 3.70043971814109 Up 0.155263505481442 CG9877 CG9877 - - - - 31973 348.00 0.01 0.285 4.83289001416474 Up 0.263802668075551 CG12640 CG12640 - - - - 38883 821.00 30.145 33.675 0.159759216311898 Up 0.321060626073174 Srp9 signal recognition particle protein 9 K03109|1|2e-39|162|dme:Dmel_CG8268|signal recognition particle subunit SRP9 GO:0048500//signal recognition particle GO:0003723//RNA binding GO:0006448//regulation of translational elongation;GO:0006613//cotranslational protein targeting to membrane 39235 356.00 23.755 18.46 -0.36382865376507 Down 0.494221371021001 CG32069 CG32069 - GO:0044425//membrane part;GO:0043231//intracellular membrane-bounded organelle - - 42850 1493.00 22.885 23.825 0.0580739221966427 Up 0.147602694492141 Atg6 Autophagy-specific gene 6 K08334|1|0.0|781|dme:Dmel_CG5429|beclin 1 - - GO:0044248//cellular catabolic process;GO:0048102//autophagic cell death 14462849 353.00 0.855 2.065 1.27214545653355 Up 0.391559899616959 40119 1652.00 3.435 2.775 -0.307822327580632 Down 0.226720380398891 CG9452 CG9452 K01078|1|0.0|845|dme:Dmel_CG9452|acid phosphatase [EC:3.1.3.2] - GO:0016791//phosphatase activity GO:0006909//phagocytosis 36998 2143.00 0.265 0.45 0.763932641766476 Up 0.138588033284903 CG11423 CG11423 K03942|1|0.0|1298|dme:Dmel_CG11423|NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] - - - 43822 3378.17 141.33 144.125 0.0282528700374194 Up 0.113360190199445 CG11155 CG11155, isoform D K05201|1|2e-91|304|rno:29559|glutamate receptor, ionotropic, kainate 1 - - - 50378 508.00 1.45 2.435 0.747868872067408 Up 0.326542068418967 CG15577 CG15577 - - - - 41639 2752.00 1.36 1.575 0.21174517713694 Up 0.115539558842953 CG8784 pyrokinin 2 receptor 1 K05053|1|3e-45|183|mmu:216749|neuromedin U receptor 2;K05052|3|3e-44|180|tgu:100220192|neuromedin U receptor 1 - - - 45739 3776.00 2.205 2.185 -0.0131453760569223 Down 0.0432901862369568 SuUR suppressor of Under-Replication - GO:0000775//chromosome, centromeric region;GO:0005720//nuclear heterochromatin;GO:0000784//nuclear chromosome, telomeric region GO:0003676//nucleic acid binding;GO:0032559 GO:0032875//regulation of DNA endoreduplication;GO:0032501//multicellular organismal process;GO:0006338//chromatin remodeling 326203 2030.00 0.65 0.64 -0.0223678130284546 Down 0.0413749834896315 CG32238 CG32238 K05755|1|1e-22|107|ecb:100058358|actin related protein 2/3 complex, subunit 4;K06047|4|2e-16|87.8|bfo:BRAFLDRAFT_65827|tubulin---tyrosine ligase [EC:6.3.2.25] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0018212 41182 3155.30 31.465 41.495 0.399189564398127 Up 0.554352133139612 FoxP forkhead box P, isoform D K09409|1|0.0|916|dme:Dmel_CG16899|forkhead box protein P GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0016564//transcription repressor activity GO:0032583;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0002377//immunoglobulin production;GO:0002520//immune system development;GO:0030323//respiratory tube development;GO:0030154//cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation 14462416 994.00 0.655 0.505 -0.375211518785656 Down 0.111345925241051 42918 11027.00 8.45 11.255 0.413542810284609 Up 0.440463611147801 nAcRalpha-96Aa nicotinic acetylcholine receptor alpha1, isoform C K05312|1|0.0|1078|dan:Dana_GF20712|nicotinic acetylcholine receptor, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 8674075 1598.00 2.275 0.44 -2.37029111644876 Down 0.504721965394268 CG42526 CG42526 K09427|1|8e-07|55.5|spu:578387|Adh transcription factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0030003//cellular cation homeostasis;GO:0010467//gene expression;GO:0010038//response to metal ion 33262 3618.60 23.72 29.5 0.314610944590562 Up 0.474342887333245 dock dreadlocks, isoform D K07365|1|0.0|843|dsi:Dsim_GD23050|NCK adaptor protein GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0030674//protein binding, bridging;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0005102//receptor binding GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation 43009 1012.00 7.215 6.67 -0.113312633306613 Down 0.15453704926694 CG11920 CG11920 - - GO:0016876//ligase activity, forming aminoacyl-tRNA and related compounds;GO:0032559 GO:0010467//gene expression 35777 1978.00 4.88 2.96 -0.721283971933937 Down 0.432769779421477 CG8713 CG8713 K05323|1|1e-14|81.6|cel:C52B9.6|potassium channel subfamily K, invertebrate;K04913|3|9e-14|79.0|dre:559728|potassium channel subfamily K member 2 GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 38440 1381.00 0.115 0.095 -0.275634442613427 Down 0.0530973451327434 CG10858 pickpocket 27 K04832|1|2e-07|57.4|cin:494365|amiloride-sensitive cation channel 5, intestinal GO:0044464//cell part GO:0005261//cation channel activity GO:0030001//metal ion transport 32462 1592.00 9.245 9.63 0.0588624784392633 Up 0.111940298507463 CG9123 CG9123 - - - - 19835327 447.00 0.48 0.54 0.169925001442312 Up 0.0680227182670717 32125 3095.52 14.41 14.89 0.0472734184073525 Up 0.114714040417382 Tango10 transport and golgi organization 10, isoform C K10445|1|4e-19|97.4|bfo:BRAFLDRAFT_58798|kelch-like protein 7;K10461|2|5e-17|90.5|xtr:779790|kelch-like protein 24/35;K10447|4|3e-16|87.8|bfo:BRAFLDRAFT_223623|kelch-like protein 9/13;K10450|5|7e-16|86.7|xtr:100127776|kelch-like protein 12 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 31260 3109.48 1.565 1.825 0.221733806834761 Up 0.127228899749042 CG2694 CG2694, isoform D - - - - 35124 2357.41 10.565 12.485 0.240903053993272 Up 0.330801743494915 CG10338 CG10338, isoform B - - - - 33543 3475.00 1.96 2.31 0.237039197300849 Up 0.151565182934883 CG3277 CG3277 K12378|1|6e-65|249|bfo:BRAFLDRAFT_86594|tyrosine-protein kinase receptor torso [EC:2.7.10.1];K05097|2|4e-57|223|gga:395742|FMS-like tyrosine kinase 4 [EC:2.7.10.1];K05098|5|3e-56|220|dre:554230|kinase insert domain protein receptor [EC:2.7.10.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 40532 1280.53 1.58 1.245 -0.343778816109022 Down 0.165235768062343 CG14642 CG14642, isoform C K01312|1|2e-30|134|dpo:Dpse_GA19543|trypsin [EC:3.4.21.4];K09641|2|6e-22|105|bta:521615|transmembrane protease, serine 11D [EC:3.4.21.-];K01316|3|8e-22|105|bta:282009|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 36929 2594.13 8.66 7.795 -0.15181800202894 Down 0.209945845991283 CG30456 CG30456, isoform D K08810|1|9e-22|105|gga:424253|triple functional domain protein [EC:2.7.11.-] - - - 36834 823.50 1.2 1.22 0.0238467419543677 Up 0.0440166424514595 CG15711 CG15711, isoform B - - - - 43747 2660.00 19.745 21.07 0.0937029463569578 Up 0.194128912957337 sip3 septin interacting protein 3, isoform B K10601|1|0.0|958|dme:Dmel_CG1937|E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043161//proteasomal ubiquitin-dependent protein catabolic process 246406 728.85 30.13 48.645 0.691090851582499 Up 0.656188086118082 CG30033 CG30033, isoform C K00528|1|2e-34|144|dme:Dmel_CG12390|ferredoxin--NADP+ reductase [EC:1.18.1.2] GO:0031980;GO:0031980 GO:0008937//ferredoxin-NAD(P) reductase activity;GO:0008937//ferredoxin-NAD(P) reductase activity GO:0007635//chemosensory behavior;GO:0018988;GO:0007617//mating behavior;GO:0019748//secondary metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0008203//cholesterol metabolic process;GO:0007635//chemosensory behavior;GO:0018988;GO:0007617//mating behavior;GO:0019748//secondary metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0008203//cholesterol metabolic process 117368 2177.00 12.705 12.44 -0.0304098899227523 Down 0.0834434024567428 prt portabella K08155|1|2e-75|283|rno:25549|MFS transporter, DHA1 family, solute carrier family 18 (vesicular monoamine) - - GO:0006810//transport;GO:0042221//response to chemical stimulus 19836000 981.00 7.765 9.83 0.340205491953279 Up 0.381983885880333 39375 1412.00 10.935 9.58 -0.190855659311913 Down 0.271595562012944 ssp sunspot - - GO:0003676//nucleic acid binding - 192528 1680.00 1.585 1.195 -0.407472222158659 Down 0.1828028001585 CG31381 CG31381, isoform B K00791|1|0.0|895|dme:Dmel_CG31381|tRNA dimethylallyltransferase [EC:2.5.1.75] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559;GO:0046914//transition metal ion binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032559 GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process 33142 1756.00 0.58 0.645 0.153246260295682 Up 0.0670320961563862 CG17599 CG17599 - - - - 12798305 468.00 0.445 1.785 2.0040468330627 Up 0.436831330075287 CG43057 CG43057, isoform B - - - - 12797891 865.00 3.74 3.145 -0.249978253008348 Down 0.201657640998547 10178858 361.00 5.21 5.435 0.0609966627488012 Up 0.09047681944261 CG42644 CG42644 - - - - 43170 1069.00 0.815 0.77 -0.081941613536176 Down 0.0531303658697662 CG14544 CG14544 K07442|1|0.0|640|dme:Dmel_CG14544|tRNA (adenine-N1-)-methyltransferase [EC:2.1.1.36] - GO:0016426 GO:0001510//RNA methylation 42839 1733.95 57.78 40.88 -0.499175007626994 Down 0.612732796196011 CG5902 CG5902, isoform C - - - GO:0050896//response to stimulus;GO:0050896//response to stimulus;GO:0050896//response to stimulus 34206 3160.00 2.47 2.31 -0.0966181901686199 Down 0.086052040681548 CG9468 CG9468 K12311|1|0.0|2040|dme:Dmel_CG9468|lysosomal alpha-mannosidase [EC:3.2.1.24] - GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0019318//hexose metabolic process 318913 613.76 109.435 83.42 -0.391609003888568 Down 0.582452780346057 CG33178 CG33178, isoform C K00799|1|7e-36|149|dpo:Dpse_GA14506|glutathione S-transferase [EC:2.5.1.18];K05309|4|5e-17|87.0|tgu:100226316|prostaglandin-E synthase [EC:5.3.99.3] GO:0044444//cytoplasmic part - - 19834814 1424.00 0.35 0.26 -0.428843298803874 Down 0.0916655659754326 - CG44314, isoform C - - - - 19835525 351.00 0.125 0.145 0.214124805352848 Up 0.0516774534407608 - CG44624 - - - - 32977 3314.50 46.785 42.005 -0.155484986354561 Down 0.334268920882314 Ubqn ubiquilin, isoform B K04523|1|0.0|788|dme:Dmel_CG14224|ubiquilin - - - 40476 1463.00 2.58 3.96 0.618129364656355 Up 0.367157574957073 CG14459 CG14459 - - - - 40568 3404.00 0.665 0.31 -1.10108612511431 Down 0.210540219257694 CG14651 CG14651 K10408|1|4e-101|370|phu:Phum_PHUM060630|dynein heavy chain, axonemal - - - 318782 1171.00 0.36 0.445 0.305808429524085 Up 0.0872077664773478 CG31525 CG31525 - - - - 42580 836.00 31.16 11.9 -1.38873365986636 Down 0.7219653942676 dnd dead end K07944|1|6e-100|363|dsi:Dsim_GD18491|ADP-ribosylation factor-like 3 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0012505//endomembrane system GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0001883//purine nucleoside binding;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0010927;GO:0019538//protein metabolic process;GO:0035146 39300 312.00 0.16 0.35 1.12928301694497 Up 0.149220710606261 CG14137 CG14137 - - - - 35293 3592.00 0.81 0.955 0.237578825151124 Up 0.0991612732796196 neb nebbish K06026|1|0.0|2044|dme:Dmel_CG10718| [EC:3.6.4.4];K10392|2|6e-145|515|phu:Phum_PHUM249670|kinesin family member 1/13/14 GO:0005875//microtubule associated complex GO:0003777//microtubule motor activity;GO:0019903//protein phosphatase binding;GO:0032559 GO:0000070//mitotic sister chromatid segregation;GO:0007292//female gamete generation;GO:0007017//microtubule-based process;GO:0003006//developmental process involved in reproduction 31120 3038.00 16.54 14.405 -0.199389574011404 Down 0.320466252806763 hfw halfway, isoform B K04660|1|6e-08|60.1|ecb:100034120|decorin - - - 38037 3142.58 5.22 5.01 -0.0592392033746761 Down 0.088033284902919 pyx pyrexia, isoform B K04984|1|1e-30|135|dre:474351|transient receptor potential cation channel subfamily A member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005216//ion channel activity;GO:0005216//ion channel activity GO:0051262//protein tetramerization;GO:0070838//divalent metal ion transport;GO:0006950//response to stress;GO:0051262//protein tetramerization;GO:0070838//divalent metal ion transport;GO:0006950//response to stress 36585 1867.00 14.77 15.095 0.0314009307488357 Up 0.0879672434288733 beta4GalNAcTA beta4GalNAcTA K07968|1|2e-61|236|cbr:CBG22165|beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-];K07966|3|2e-56|220|cin:100175041|beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-];K07967|5|1e-53|211|xla:100190782|beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0008376//acetylgalactosaminyltransferase activity GO:0048741//skeletal muscle fiber development;GO:0006041//glucosamine metabolic process;GO:0007626//locomotory behavior;GO:0006664//glycolipid metabolic process 42386 932.00 13.27 14.575 0.135327512717665 Up 0.239037115308414 CG17190 CG17190 - - - - 39860 2735.82 69.095 61.655 -0.164363418229473 Down 0.347675340113591 Baldspot baldspot, isoform B K10203|1|1e-68|261|gga:428772|elongation of very long chain fatty acids protein 6 [EC:2.3.1.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0048232//male gamete generation;GO:0048232//male gamete generation 14462830 886.00 0.135 0.25 0.888968687611256 Up 0.108274996697926 CG43915 CG43915 - - - - 43905 4967.90 31.825 32.35 0.0236051980911497 Up 0.0835424646678114 syd sunday driver, isoform K K04436|1|0.0|661|gga:426986|mitogen-activated protein kinase 8 interacting protein 3 GO:0031224//intrinsic to membrane;GO:0012505//endomembrane system;GO:0005798//Golgi-associated vesicle;GO:0031224//intrinsic to membrane;GO:0012505//endomembrane system;GO:0005798//Golgi-associated vesicle;GO:0031224//intrinsic to membrane;GO:0012505//endomembrane system;GO:0005798//Golgi-associated vesicle;GO:0031224//intrinsic to membrane;GO:0012505//endomembrane system;GO:0005798//Golgi-associated vesicle GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0030159//receptor signaling complex scaffold activity;GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0030159//receptor signaling complex scaffold activity;GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0030159//receptor signaling complex scaffold activity;GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0030159//receptor signaling complex scaffold activity GO:0043408//regulation of MAPK cascade;GO:0010970//microtubule-based transport;GO:0043408//regulation of MAPK cascade;GO:0010970//microtubule-based transport;GO:0043408//regulation of MAPK cascade;GO:0010970//microtubule-based transport;GO:0043408//regulation of MAPK cascade;GO:0010970//microtubule-based transport 3772712 143.00 0.395 0.455 0.204013892021593 Up 0.0688812574296658 32683 1935.62 0.945 1.105 0.225660135170359 Up 0.102001056663585 wus wurst, isoform B K09536|1|2e-09|64.7|bta:514510|DnaJ homolog subfamily C member 16 GO:0005768//endosome;GO:0031982//vesicle;GO:0016020//membrane GO:0005515//protein binding GO:0043062//extracellular structure organization;GO:0035151//regulation of tube size, open tracheal system;GO:0016192//vesicle-mediated transport 19835857 1240.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 43918 1002.00 175.325 193.465 0.142040862164162 Up 0.334434024567428 noe noe, isoform C - - - - 117366 1573.00 4.77 5.19 0.121745272352369 Up 0.141890106987188 Gpi1 Gpi1, isoform C K03860|1|0.0|803|dme:Dmel_CG32578|phosphatidylinositol glycan, class Q GO:0031224//intrinsic to membrane GO:0008375//acetylglucosaminyltransferase activity GO:0006497//protein lipidation 33569 755.00 282.605 260.705 -0.116368738587664 Down 0.300719852067098 Thor thor, isoform B K07205|1|5e-55|214|dpo:Dpse_GA21364|eukaryotic translation initiation factor 4E binding protein 1 - GO:0031369//translation initiation factor binding GO:0016049//cell growth;GO:0042742//defense response to bacterium;GO:0010259//multicellular organismal aging;GO:0002376//immune system process;GO:0006446//regulation of translational initiation;GO:0006639//acylglycerol metabolic process 14462831 476.00 0.18 0.1 -0.84799690655495 Down 0.0938779553559635 317935 1639.00 17.525 13.075 -0.422603497763682 Down 0.497721569145423 CG32243 CG32243 - - - - 38700 3197.75 9.995 12.565 0.330132199136028 Up 0.407740060758156 Ets65A Ets at 65A, isoform B K09436|1|0.0|767|dme:Dmel_CG7018|friend leukemia integration 1 transcription factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 32253 8534.87 13.005 17 0.386468347082073 Up 0.478008189142782 CG42629 radish, isoform N K08013|1|3e-56|221|mcc:715958|signal-induced proliferation-associated gene 1 GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0005488//binding GO:0009966//regulation of signal transduction 5740802 702.00 0.065 0.14 1.10691520391651 Up 0.0979064852727513 CG34297 CG34297 K09553|1|7e-12|70.5|dsi:Dsim_GD23015|stress-induced-phosphoprotein 1 - - - 33248 5502.64 13.52 16.01 0.243878156234073 Up 0.358175934486858 GABA-B-R3 metabotropic GABA-B receptor subtype 3, isoform H K04615|1|2e-46|187|ame:408760|gamma-aminobutyric acid (GABA) B receptor 1;K04616|2|3e-44|180|xtr:548761|gamma-aminobutyric acid (GABA) B receptor 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0008066//glutamate receptor activity;GO:0008066//glutamate receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 326194 1566.00 1.695 3.285 0.954608097185986 Up 0.419330339453177 CG32081 CG32081 - GO:0031224//intrinsic to membrane - GO:0051234//establishment of localization 32681 639.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 CG13002 CG13002 - - - - 41089 1351.36 9.285 9.985 0.104860517508552 Up 0.166919825650509 Mst85C Mst85C, isoform B - - - - 35556 822.00 0.335 0.46 0.457472765599241 Up 0.107416457535332 CG15233 CG15233 - - - - 40332 2244.58 33.33 32.505 -0.0361596632954183 Down 0.119006736230353 CG10565 CG10565, isoform B K09522|1|1e-156|553|dme:Dmel_CG10565|DnaJ homolog subfamily C member 2 - GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0010468//regulation of gene expression 12798469 581.00 0.01 0.08 3 Up 0.110718531237617 317834 759.04 38.62 35.39 -0.12600640252542 Down 0.283648131026285 CG32039 CG32039, isoform B K14014|1|5e-25|114|dme:Dmel_CG32039|small VCP/p97-interacting protein - - - 34146 1061.00 0.26 0.09 -1.53051471669878 Down 0.145588429533747 CG14273 CG14273 - - - - 19834758 560.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 43694 3765.10 31.845 38.99 0.292037282771102 Up 0.474210804385154 CG12054 CG12054, isoform F - GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 36674 2216.00 38.545 34.555 -0.157649248864567 Down 0.32680623431515 pcs parcas - GO:0044424//intracellular part GO:0004860//protein kinase inhibitor activity GO:0003002//regionalization;GO:0001708//cell fate specification;GO:0009887//organ morphogenesis;GO:0009888//tissue development;GO:0008219//cell death 246666 398.00 14.605 20.145 0.46395944731942 Up 0.533516048078193 Obp51a Odorant-binding protein 51a - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 32617 1267.10 50.23 51.025 0.022655002248252 Up 0.0871087042662792 eIF-2alpha eukaryotic translation initiation factor 2alpha, isoform B K03237|1|1e-154|545|dsi:Dsim_GD15749|translation initiation factor eIF-2 alpha subunit GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding GO:0006413//translational initiation;GO:0007052//mitotic spindle organization 37575 3553.00 30.885 27.975 -0.142768199489654 Down 0.291308942015586 dnr1 defense repressor 1, isoform B K10637|1|2e-76|287|aag:AaeL_AAEL000590|E3 ubiquitin-protein ligase MYLIP [EC:6.3.2.19] GO:0043232 GO:0046914//transition metal ion binding GO:0002809 37428 4426.00 0.6 0.815 0.441837558622559 Up 0.133403777572315 CG10505 CG10505 K10835|1|0.0|1403|dme:Dmel_CG11898|xenobiotic-transporting ATPase [EC:3.6.3.44];K05673|2|0.0|988|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|3|0.0|900|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] - - - 246504 1608.00 0.17 0.395 1.21631790692676 Up 0.165863162065777 CG30181 pickpocket 3 - GO:0044464//cell part GO:0005261//cation channel activity GO:0030001//metal ion transport 34560 4492.77 9.45 12.155 0.363163658920294 Up 0.424085325584467 ab abrupt, isoform F K02174|1|1e-32|142|dme:Dmel_CG11491|broad;K09237|2|3e-26|121|dgr:Dgri_GH18647|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007411//axon guidance;GO:0007297//ovarian follicle cell migration;GO:0048513//organ development;GO:0007033//vacuole organization;GO:0006914//autophagy;GO:0007411//axon guidance;GO:0007297//ovarian follicle cell migration;GO:0048513//organ development;GO:0007033//vacuole organization;GO:0006914//autophagy;GO:0007411//axon guidance;GO:0007297//ovarian follicle cell migration;GO:0048513//organ development;GO:0007033//vacuole organization;GO:0006914//autophagy 41459 4040.00 9.27 9.495 0.0345986615239671 Up 0.0789195614846123 CG3532 GCC185 ortholog K10352|1|6e-24|114|gga:396465|myosin heavy chain - - - 37331 4602.00 5.225 6.715 0.361956362459197 Up 0.342359001452912 CG16742 CG16742 K04574|1|3e-06|55.1|mcc:717705|neurofilament heavy polypeptide - - - 34864 1396.36 1.14 0.94 -0.278301162487104 Down 0.118676528860124 CG4480 CG4480, isoform C - - - - 34557 5299.78 28.125 37.49 0.414652729296329 Up 0.554286091665566 Ca-beta Ca2+-channel-protein-beta-subunit, isoform Q K05317|1|0.0|851|dse:Dsec_GM11112|voltage-dependent calcium channel beta, invertebrate GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0034704//calcium channel complex GO:0005262//calcium channel activity;GO:0005262//calcium channel activity;GO:0005262//calcium channel activity GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport 32495 1829.79 1.975 3.01 0.607910833695237 Up 0.31881521595562 CG8097 CG8097, isoform B K01887|1|3e-06|53.5|cfa:609803|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 37010 2582.00 11.76 11.715 -0.00553110597322892 Down 0.0472856954167217 swi2 swi2 K06850|1|9e-11|69.3|gga:374173|slit 3 - - - 2768897 607.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 Ste:CG33243 Ste:CG33243 K08282|1|1e-95|348|dme:Dmel_CG33243|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 32340 6457.79 46.3 67.705 0.548250186974156 Up 0.636474706115441 rdgB retinal degeneration B, isoform K K01106|1|1e-50|202|gga:771549|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56];K13619|2|3e-12|75.1|spu:578370|phospholipase DDHD1 [EC:3.1.1.-] GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral to membrane;GO:0005790//smooth endoplasmic reticulum GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0019829//cation-transporting ATPase activity GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance;GO:0007606//sensory perception of chemical stimulus;GO:0009586;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051234//establishment of localization;GO:0043954//cellular component maintenance 38033 928.55 21.405 22.145 0.0490331616883968 Up 0.128351604807819 thoc7 thoc7, isoform B K13176|1|1e-152|538|dme:Dmel_CG17143|THO complex subunit 7 - - GO:0006405//RNA export from nucleus;GO:0006405//RNA export from nucleus 41888 881.00 0.72 1.025 0.509555098063134 Up 0.1682076343944 CG14870 CG14870 - - - - 38263 1010.00 0.12 0.56 2.22239242133645 Up 0.259774138158764 CG11815 CG11815 - - - - 39166 883.37 8.225 6.66 -0.304493501551342 Down 0.331660282657509 CG6709 CG6709, isoform B - - - - 39366 1814.60 46.875 55.455 0.242498853750431 Up 0.439737154933298 Pop2 Pop2, isoform E K12581|1|0.0|707|dme:Dmel_CG5684|CCR4-NOT transcription complex subunit 7/8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0048513//organ development;GO:0048468//cell development;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006355//regulation of transcription, DNA-dependent;GO:0048513//organ development;GO:0048468//cell development;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006355//regulation of transcription, DNA-dependent;GO:0048513//organ development;GO:0048468//cell development;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006355//regulation of transcription, DNA-dependent;GO:0048513//organ development;GO:0048468//cell development;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 40131 2384.00 38.055 41.22 0.115258484754161 Up 0.268392550521728 CG9330 CG9330 K06158|1|0.0|1319|dme:Dmel_CG9330|ATP-binding cassette, sub-family F, member 3 GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 39542 2516.99 21.94 16.81 -0.384243801167026 Down 0.49976885484084 Hsc70-1 heat shock protein cognate 1, isoform D K03283|1|0.0|1018|dme:Dmel_CG8937|heat shock 70kDa protein 1/8 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006950//response to stress;GO:0006950//response to stress;GO:0006950//response to stress 36846 3548.01 22.005 19.165 -0.199357373594028 Down 0.345033681151763 Sema-2a Sema-2a, isoform E K06842|1|8e-92|338|bfo:BRAFLDRAFT_279857|semaphorin 6 GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0004871//signal transducer activity GO:0006935//chemotaxis;GO:0007631//feeding behavior;GO:0008039//synaptic target recognition;GO:0035272//exocrine system development;GO:0006935//chemotaxis;GO:0007631//feeding behavior;GO:0008039//synaptic target recognition;GO:0035272//exocrine system development 32324 4434.58 19.79 25.805 0.382879018236538 Up 0.51367058512746 CG15760 CG15760, isoform C - - - - 36366 2107.00 4.95 2.99 -0.727283040768867 Down 0.437359661867653 CG8550 CG8550 K08635|1|2e-15|84.7|bta:616991|membrane metallo-endopeptidase-like 1;K08636|2|3e-15|84.0|ssc:100154258|phosphate-regulating neutral endopeptidase [EC:3.4.24.-] GO:0016020//membrane GO:0004872//receptor activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0023052//signaling 37301 1421.09 29.6 26.48 -0.160694053709094 Down 0.315678245938449 CG11200 carbonyl reductase, isoform C K11170|1|2e-44|180|cfa:609792|dehydrogenase/reductase SDR family member X [EC:1.1.-.-] - - - 42471 2742.00 0.325 0.35 0.106915203916512 Up 0.0478470479461102 Ir93a ionotropic receptor 93a K05206|1|3e-24|114|xtr:100125089|glutamate receptor, ionotropic, delta 1;K05207|2|1e-23|112|gga:422520|glutamate receptor, ionotropic, delta 2 GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 35252 1009.48 48.475 54.795 0.17680335608902 Up 0.367884031171576 CG13077 CG13077, isoform B K08371|1|2e-13|77.0|dpo:Dpse_GA10125|cytochrome b-561 domain containing 2 - - - 32142 5024.98 13.745 11.405 -0.269240460200816 Down 0.367917051908599 ATP7 ATP7, isoform C K01533|1|0.0|2273|dme:Dmel_CG1886|Cu2+-exporting ATPase [EC:3.6.3.4] GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0043682//copper-transporting ATPase activity;GO:0032559 GO:0009206;GO:0000041//transition metal ion transport 41305 1448.86 27.94 25.095 -0.154932074649954 Down 0.300818914278167 CG4511 CG4511, isoform B K08327|1|6e-06|52.4|gga:429078|phosducin - - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis 41469 6348.49 10.275 13.295 0.371745383288622 Up 0.440562673358869 CG14741 CG14741, isoform I K01530|1|0.0|3116|dme:Dmel_CG14741|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559 GO:0009206;GO:0006869//lipid transport 43663 1906.00 10.05 8.095 -0.312092515763725 Down 0.365836745476159 Cyp4c3 cytochrome P450-4c3 K00517|1|0.0|1051|dme:Dmel_CG1438| [EC:1.14.-.-];K07427|2|6e-135|481|dre:562008|cytochrome P450, family 4, subfamily V GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0030908//protein splicing 38555 2603.00 229.535 53.94 -2.08928672902915 Down 0.793059041077797 CG13722 CG13722 K10955|1|1e-13|78.6|tgu:100220116|intestinal mucin-2;K13908|3|5e-09|63.2|hsa:727897|mucin-5B - - - 35335 2809.99 48.36 45.715 -0.081146624710735 Down 0.20307753269053 CG9318 CG9318, isoform B - GO:0031224//intrinsic to membrane - - 19835455 1264.00 6.32 3.78 -0.74153832395603 Down 0.480748910315678 317955 360.00 0.835 0.01 -6.38370429247405 Down 0.461134592524105 Drsl3 Drosomycin-like 3 - - - GO:0006952//defense response 5740761 527.00 4.855 11.64 1.26154785748909 Up 0.646942279751684 CG34445 CG34445 - - - - 36522 3706.00 0.09 0.125 0.473931188332412 Up 0.0617157574957073 CG6280 CG6280 - - - - 39679 1413.00 52.4 56.18 0.100489812701586 Up 0.243527935543521 CG7945 CG7945, isoform B K09556|1|2e-105|382|dan:Dana_GF10728|BCL2-associated athanogene 2 - GO:0005515//protein binding;GO:0005515//protein binding - 39813 964.73 146.4 192.41 0.394268227687149 Up 0.591566503764364 CG4893 CG45057, isoform E - - - - 42022 1712.00 1.92 3.085 0.684164178428262 Up 0.345363888521992 CG17560 CG17560 K13356|1|1e-88|327|api:100161452|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 36840 939.00 101.075 71.12 -0.507098974329287 Down 0.633172632413155 CG4409 CG4409 - - - - 19835736 613.00 3.285 4.57 0.47630079473574 Up 0.341005151234976 44110 656.11 243.26 392.94 0.691809923947683 Up 0.69346849821688 Mgstl microsomal glutathione S-transferase-like, isoform C K00799|1|2e-63|241|dme:Dmel_CG1742|glutathione S-transferase [EC:2.5.1.18] GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups - 40353 2124.00 0.04 0.025 -0.678071905112638 Down 0.0550785893541144 Cpr78Cb cuticular protein 78Cb, isoform B - - GO:0005214//structural constituent of chitin-based cuticle - 42848 3256.83 49.145 48.92 -0.00662024073431851 Down 0.0615836745476159 Rox8 Rox8, isoform H K13201|1|3e-81|303|ecb:100058604|nucleolysin TIAR GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000166//nucleotide binding;GO:0000166//nucleotide binding;GO:0000166//nucleotide binding;GO:0000166//nucleotide binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0050794//regulation of cellular process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0050794//regulation of cellular process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0050794//regulation of cellular process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0050794//regulation of cellular process 31361 957.01 0.72 0.905 0.329920885640893 Up 0.122209747721569 dgt4 dim gamma-tubulin 4, isoform C - GO:0015630//microtubule cytoskeleton - GO:0007067//mitosis 40025 1548.00 0.54 0.825 0.611434712082347 Up 0.162429005415401 CG18233 CG18233 K00472|1|6e-92|338|dan:Dana_GF23629|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 41908 974.00 0.8 1.205 0.590961241342599 Up 0.196341302337868 CG9589 CG9589 K01719|1|6e-56|217|dmo:Dmoj_GI15566|uroporphyrinogen-III synthase [EC:4.2.1.75] - - - 14462520 931.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 3354918 723.12 1282.555 1141.15 -0.168532253382879 Down 0.390206049399023 RpL15 ribosomal protein L15, isoform I K02877|1|2e-100|365|dya:Dyak_GE19709|large subunit ribosomal protein L15e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression 3355145 2338.13 33.84 38.59 0.189497475421305 Up 0.367256637168142 CG12547 CG12547, isoform C - - GO:0003824//catalytic activity GO:0019725//cellular homeostasis 19836218 225.00 0.215 0.01 -4.4262647547021 Down 0.216153744551578 41082 2458.76 77.245 74.195 -0.0581195847516536 Down 0.172764496103553 CG11984 CG11984, isoform I K10668|1|2e-08|61.2|xtr:549183|E3 ubiquitin-protein ligase RNF138 [EC:6.3.2.19] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 19835593 1012.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 40295 4254.00 10.64 13.325 0.324637382145348 Up 0.40952318055739 CG11399 CG11399 - - GO:0005488//binding GO:0007450//dorsal/ventral pattern formation, imaginal disc 41352 487.00 9.64 8.905 -0.114417535128343 Down 0.175009906221107 CG14701 CG14701 - - - - 318872 5885.30 22.755 23.665 0.056571335770174 Up 0.146380927222296 CG34126 CG34126, isoform G - - - - 41135 1862.00 2.52 0.995 -1.34065530295627 Down 0.43617091533483 CG8147 CG8147 K01077|1|0.0|1050|dme:Dmel_CG8147|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 3885638 871.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 CG33986 CG33986 K01183|1|8e-14|77.4|dme:Dmel_CG18140|chitinase [EC:3.2.1.14];K01873|2|1e-10|66.6|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 42347 2921.00 0.07 0.055 -0.347923303420307 Down 0.0540219257693832 CG7432 CG7432 K01316|1|4e-37|157|ptr:458478|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K09628|3|2e-36|154|xla:397795|protease, serine 27 [EC:3.4.21.-];K01323|4|2e-36|154|mdo:100013939|coagulation factor XI [EC:3.4.21.27] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 40265 1642.18 4.115 4.14 0.00873833707769927 Up 0.0432901862369568 CG5199 CG5199, isoform B - - - GO:0034629//cellular protein complex localization 33885 1514.00 81.27 63.02 -0.366913139905631 Down 0.563498877294941 CG9498 CG9498 - - - - 40657 1335.00 16.25 17.425 0.100718937952606 Up 0.197662131818782 Snr1 Snf5-related 1 K11648|1|0.0|662|dsi:Dsim_GD19788|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 GO:0031981//nuclear lumen;GO:0070603//SWI/SNF superfamily-type complex;GO:0001739//sex chromatin GO:0003712//transcription cofactor activity;GO:0019904//protein domain specific binding GO:0009888//tissue development;GO:0048812//neuron projection morphogenesis;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0001824//blastocyst development;GO:0006259//DNA metabolic process;GO:0003002//regionalization;GO:0010551;GO:0043388//positive regulation of DNA binding;GO:0016568//chromatin modification;GO:0007476//imaginal disc-derived wing morphogenesis 50147 982.00 3.52 1.95 -0.852101304887686 Down 0.409391097609299 CG9445 CG9445, isoform B - - - - 42600 5319.77 31.595 26.005 -0.280907227874879 Down 0.451525558050456 CG42390 CG42390, isoform E K06102|1|2e-13|79.3|xla:398149|cingulin;K08282|2|3e-13|78.6|spu:579556|non-specific serine/threonine protein kinase [EC:2.7.11.1];K10352|3|4e-13|78.2|dre:567740|myosin heavy chain - - - 3772246 382.00 13.23 15.665 0.243731708092377 Up 0.356095628054418 31727 1146.00 1.74 1.245 -0.482941563780648 Down 0.21443666622639 CG2256 CG2256 K11837|1|4e-08|59.3|bfo:BRAFLDRAFT_121867|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15];K06268|2|1e-07|57.8|hmg:100213359|protein phosphatase 3, regulatory subunit;K08328|3|1e-07|57.4|rno:301233|guanylate cyclase activator 1 - - - 40087 1182.00 3.825 4.975 0.379236777850997 Up 0.309701492537313 Gem2 Gemin2, isoform B K13130|1|1e-129|462|dme:Dmel_CG10419|survival of motor neuron protein-interacting protein 1 - - GO:0000398//mRNA splicing, via spliceosome 31905 5148.78 9.7 11.7 0.270451877396277 Up 0.349788667283054 CG42797 CG42797, isoform F K12168|1|0.0|751|dme:Dmel_CG3099|E3 ubiquitin-protein ligase HECW2 [EC:6.3.2.19] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 8673981 483.06 4.12 14.66 1.83116886095059 Up 0.708492933562277 Sfp26Ad seminal fluid protein 26Ad, isoform B - - - - 34393 2063.00 47.22 55.765 0.239961880324995 Up 0.439605071985207 CG5375 CG5375 - - - - 31102 1082.00 0.99 0.85 -0.219965683941908 Down 0.0953969092590147 CG14780 CG14780 K01362|1|2e-171|601|dme:Dmel_CG14780| [EC:3.4.21.-];K01312|3|1e-34|147|dpo:Dpse_GA11598|trypsin [EC:3.4.21.4] - - - 38424 4028.05 19.06 19.195 0.0101824409370075 Up 0.0570268128384626 sty sprouty, isoform C K04704|1|0.0|700|dme:Dmel_CG1921|sprouty GO:0044464//cell part;GO:0044464//cell part - GO:0042478//regulation of eye photoreceptor cell development;GO:0007389//pattern specification process;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009966//regulation of signal transduction;GO:0060446//branching involved in open tracheal system development;GO:0048523//negative regulation of cellular process;GO:0035466;GO:0042478//regulation of eye photoreceptor cell development;GO:0007389//pattern specification process;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009966//regulation of signal transduction;GO:0060446//branching involved in open tracheal system development;GO:0048523//negative regulation of cellular process;GO:0035466 38222 3550.27 13.355 14.135 0.0818919071960654 Up 0.158499537709682 CG13921 CG13921, isoform F - - - - 39660 1662.00 0.07 0.105 0.584962500721156 Up 0.0687491744815744 Best4 bestrophin 4 K13881|1|2e-100|366|rno:689103|bestrophin-4;K13878|5|5e-99|361|xtr:100302038|bestrophin-1 - - - 40445 2096.00 0.685 1.275 0.896321353898331 Up 0.262217672698455 CG7140 CG7140 K00036|1|0.0|1092|dme:Dmel_CG7140|glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0019318//hexose metabolic process 42252 281.00 1.645 0.395 -2.05816302555814 Down 0.425538238013472 CG14302 CG14302 - - - - 43102 1682.05 242.605 241.95 -0.0039003449653537 Down 0.0471866332056532 CG5028 CG5028, isoform D K00030|1|0.0|772|dme:Dmel_CG5028|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0009060//aerobic respiration;GO:0009060//aerobic respiration;GO:0009060//aerobic respiration;GO:0009060//aerobic respiration 44317 1212.98 118.14 148.69 0.331810106540789 Up 0.550917976489235 CanB calcineurin B, isoform B K06268|1|2e-93|342|dvi:Dvir_GJ14779|protein phosphatase 3, regulatory subunit GO:0008287//protein serine/threonine phosphatase complex;GO:0030136//clathrin-coated vesicle GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0004722//protein serine/threonine phosphatase activity GO:0014866//skeletal myofibril assembly;GO:0006464//cellular protein modification process;GO:0001505//regulation of neurotransmitter levels;GO:0022403;GO:0042993//positive regulation of transcription factor import into nucleus 12798340 330.50 10.235 10.415 0.025151737017236 Up 0.073702285035002 CG43071 CG43071, isoform C - - - - 42992 489.00 35.715 36.565 0.03393324069641 Up 0.104411570466253 CG11781 CG11781 - GO:0031224//intrinsic to membrane - - 43124 1520.00 0.055 0.255 2.2129937233342 Up 0.167217012283714 alpha4GT2 alpha4GT2 K01988|1|0.0|705|dme:Dmel_CG5878|lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228] GO:0044431//Golgi apparatus part GO:0008376//acetylgalactosaminyltransferase activity GO:0008593//regulation of Notch signaling pathway;GO:0006687//glycosphingolipid metabolic process 19834841 470.00 1.485 0.01 -7.21431912080077 Down 0.591731607449478 41971 2497.00 3.195 3.65 0.192080532820385 Up 0.166193369436006 asun asunder - - - - 8674004 654.00 7.01 7.14 0.0265096300184766 Up 0.0667349095231806 CG42495 CG42495 - - - - 36222 426.00 0.22 0.465 1.07972719247073 Up 0.171212521463479 CG13202 CG13202 K01530|1|4e-07|52.8|ame:413138|phospholipid-translocating ATPase [EC:3.6.3.1] - - - 19835202 231.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 43783 2811.34 112.965 131.475 0.218912645841543 Up 0.440628714832915 Syt7 synaptotagmin 7, isoform M K01104|1|2e-66|254|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|4|2e-31|138|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10] - - - 3772012 665.79 27.425 30.43 0.150002713224041 Up 0.303493593977018 CG17768 CG17768, isoform B K12623|1|2e-70|264|dsi:Dsim_GD22262|U6 snRNA-associated Sm-like protein LSm4 GO:0032991//macromolecular complex GO:0005488//binding - 38793 1557.00 5.675 4.99 -0.185580576841017 Down 0.201723682472593 BHD Birt-Hogg-Dube homolog K09594|1|0.0|923|dme:Dmel_CG8616|folliculin GO:0044424//intracellular part - GO:0019827//stem cell maintenance 50206 198.00 547.28 283.335 -0.949770308189136 Down 0.731079117685907 CG15068 CG15068 - - - - 326171 846.00 18.905 18.98 0.00571214303387482 Up 0.0513802668075551 CG31917 CG31917 K11663|1|1e-77|289|dme:Dmel_CG31917|zinc finger HIT domain-containing protein 1 - - - 4379878 327.00 28.98 30.975 0.0960466874710344 Up 0.22358341038172 mRpL34 mitochondrial ribosomal protein L34 - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 35763 1001.00 0.775 0.565 -0.45594544285905 Down 0.134394399683001 Dic3 dicarboxylate carrier 3, isoform B K13577|1|2e-76|285|cel:K11G12.5|mitochondrial dicarboxylate carrier GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 19835269 1361.00 0.91 0.705 -0.368243287799903 Down 0.13010170387003 14462441 1205.44 13.855 13.43 -0.0449474060539747 Down 0.103751155725796 41068 1885.00 11.34 9.18 -0.304854581528421 Down 0.374157971205917 CG11964 CG11964 K12864|1|0.0|1047|dme:Dmel_CG11964|beta-catenin-like protein 1 - - - 43665 1112.00 0.28 0.31 0.146841388329271 Up 0.0552767137762515 CG15549 CG15549 - - - - 41283 1661.00 0.525 0.915 0.80145432061792 Up 0.206115440496632 CG14689 CG14689 - - - - 42218 2167.00 41.815 48.055 0.200665984574007 Up 0.389512613921543 CG12333 CG12333 K12862|1|5e-19|96.7|dre:100004402|pleiotropic regulator 1;K03130|2|6e-19|96.3|phu:Phum_PHUM147630|transcription initiation factor TFIID subunit D4;K01062|4|6e-19|96.3|dre:394247|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - - - 41989 1569.00 18.015 20.735 0.202869395479171 Up 0.341764628186501 CG17565 CG17565 K05954|1|0.0|844|dme:Dmel_CG17565|protein farnesyltransferase subunit beta [EC:2.5.1.58] - - - 35689 2379.00 0.89 1.295 0.541074856720156 Up 0.194062871483292 CG2137 CG2137 K00111|1|0.0|1397|dme:Dmel_CG2137|glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0046872//metal ion binding GO:0006071//glycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0022904//respiratory electron transport chain 35591 598.00 27.64 27.28 -0.018913971364086 Down 0.0791507066437723 CG15237 CG15237 - - - - 42436 464.00 33.29 27.825 -0.258707182910941 Down 0.434057588165368 Srp14 signal recognition particle protein 14 K03104|1|2e-56|216|dya:Dyak_GE25671|signal recognition particle subunit SRP14 GO:0048500//signal recognition particle GO:0003723//RNA binding;GO:0005048//signal sequence binding GO:0006448//regulation of translational elongation;GO:0006613//cotranslational protein targeting to membrane 42301 987.00 0.55 0.445 -0.305626282558262 Down 0.0941421212521464 CG14282 CG14282 - - - - 326110 411.00 0.225 0.28 0.31550182572793 Up 0.0761127988376701 Obp57e Odorant-binding protein 57e - - GO:0005488//binding GO:0051234//establishment of localization 43203 1002.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 TwdlL TweedleL, isoform B - - - - 32098 977.42 95.67 88.95 -0.105071992818895 Down 0.270373794743099 CG1572 CG1572, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 42691 3079.30 41.215 39.865 -0.0480468257604809 Down 0.142979791308942 CG6982 CG45049, isoform F - GO:0031224//intrinsic to membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic to membrane;GO:0043296//apical junction complex - GO:0021782//glial cell development;GO:0021782//glial cell development 19835608 1672.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 38751 2267.20 3.585 9.255 1.36825987116867 Up 0.635550125478801 CG32392 CG32392, isoform B - - GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0009987//cellular process;GO:0009987//cellular process 3355108 364.00 180.31 171.98 -0.0682386109791526 Down 0.199181085721833 CG41128 CG41128 - - - - 42174 903.00 29.33 22.575 -0.377651083388735 Down 0.521991810857218 CG12321 CG12321 K11876|1|3e-140|497|dme:Dmel_CG12321|proteasome assembly chaperone 2 - - - 43833 3022.70 42.445 47.51 0.162636591723321 Up 0.336514330999868 toy twin of eyeless, isoform C K08031|1|2e-110|400|rno:25509|paired box protein 6 - - - 318700 721.00 1.765 1.225 -0.52688643426861 Down 0.226126007132479 CG31373 CG31373 K01462|1|9e-112|402|dme:Dmel_CG31373| [EC:3.5.1.88] - GO:0046914//transition metal ion binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0010467//gene expression 42781 2088.00 0.3 0.07 -2.09953567355091 Down 0.179863954563466 CG16723 CG16723 K00680|1|0.0|744|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 43184 3707.06 12.73 15.19 0.254889450600725 Up 0.362501651036851 CG6154 CG6154, isoform D K01273|1|0.0|854|dme:Dmel_CG6154|membrane dipeptidase [EC:3.4.13.19] - GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 41992 3576.82 21.455 23.42 0.12642717475283 Up 0.259113723418307 ema endosomal maturation defective, isoform C - - - - 19834889 688.00 0.12 0.085 -0.497499659470817 Down 0.0682538634262317 40042 713.00 16.145 9.2 -0.811381674669606 Down 0.613690397569674 MED11 mediator complex subunit 11 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 43279 1064.00 1.575 1.345 -0.227745655830655 Down 0.119733192444855 CG17991 CG17991 K10660|1|5e-173|606|dme:Dmel_CG17991|E3 ubiquitin-protein ligase MARCH5 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 36338 829.39 7.425 9.085 0.291095488545988 Up 0.335919957733457 CG8490 CG8490, isoform B - - - - 32113 556.66 10.61 10.68 0.00948699077278907 Up 0.0513802668075551 CG15220 replication protein A3, isoform B - - GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process 41409 2886.00 12.415 12.145 -0.0317217715409758 Down 0.0834434024567428 CG6834 CG6834 - - - - 326234 1841.16 73.77 68.63 -0.104194880973655 Down 0.249273543785497 l(1)G0320 lethal (1) G0320, isoform B K13249|1|1e-120|433|dse:Dsec_GM11361|translocon-associated protein subunit alpha GO:0044444//cytoplasmic part GO:0042277//peptide binding - 38183 1807.00 4.5 2 -1.16992500144231 Down 0.511227050587769 CG12003 CG12003 - - - - 36137 1100.00 18.97 19.71 0.0552080976320103 Up 0.139347510236428 CG12341 CG12341 - - - - 8673991 258.00 0.01 0.245 4.61470984411521 Up 0.239499405626734 CG42581 CG42581 - - - - 4379834 8235.31 56.345 69.985 0.312758147256935 Up 0.516609430722494 stnB stoned B, isoform H K03122|1|3e-50|202|gga:421307|transcription initiation factor TFIIA large subunit GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding;GO:0005488//binding GO:0008344//adult locomotory behavior;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0008344//adult locomotory behavior;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006897//endocytosis;GO:0015031//protein transport 31230 2412.00 14.2 13.445 -0.0788211745191714 Down 0.156749438647471 z zeste, isoform C K09362|1|4e-121|436|dme:Dmel_CG7803|homeo domain only family, other - - - 31497 3376.18 4.305 7.665 0.832272554261934 Up 0.529718663320565 CG4078 CG4078, isoform B K11136|1|0.0|1845|dme:Dmel_CG4078|regulator of telomere elongation helicase 1 - - - 33708 866.00 21.65 6.575 -1.71930422543442 Down 0.726522255976753 Jon25Bi jonah 25Bi K01310|1|1e-81|302|dpo:Dpse_GA21380|chymotrypsin [EC:3.4.21.1];K01362|3|1e-80|299|dme:Dmel_CG31034| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 5740414 7165.75 8 6.955 -0.201949485232486 Down 0.247160216616035 Snoo Sno oncogene, isoform G - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0048468//cell development;GO:0008101//decapentaplegic signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0048468//cell development;GO:0008101//decapentaplegic signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0048468//cell development;GO:0008101//decapentaplegic signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway 32299 1220.00 73.705 63 -0.226410663577873 Down 0.438614449874521 GstT4 glutathione S transferase T4 K00799|1|5e-126|450|dme:Dmel_CG1681|glutathione S-transferase [EC:2.5.1.18] - - - 43474 416.00 0.01 0.23 4.52356195605701 Up 0.229362039360719 Diedel diedel - - - - 40906 1749.00 0.715 1.015 0.505464580406787 Up 0.165103685114252 alpha-Est4 alpha-Esterase-4 K01044|1|0.0|1113|dme:Dmel_CG1082|carboxylesterase [EC:3.1.1.1];K03927|4|3e-115|416|dan:Dana_GF17295|carboxylesterase type B [EC:3.1.1.1] - GO:0016788//hydrolase activity, acting on ester bonds - 19834928 1024.00 0.2 0.14 -0.514573172829758 Down 0.0790516444327037 39188 1605.00 1.695 1.385 -0.291399297087155 Down 0.151135913353586 CG32055 CG32055 K13023|1|8e-26|118|ecb:100069043|carboxypeptidase N regulatory subunit - GO:0005488//binding - 36479 614.00 0.185 0.68 1.87800947562139 Up 0.272057852331264 CG17048 CG17048, isoform B K11997|1|3e-06|51.6|spu:583781|tripartite motif-containing protein 2/3 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 35386 2391.00 6.815 6.4 -0.090641751917847 Down 0.128978998811253 CG9246 CG9246 - - - - 42742 3018.52 11.165 8.025 -0.476409953812808 Down 0.473286223748514 Ir inwardly rectifying potassium channel 1, isoform H K05330|1|3e-96|353|cel:M02A10.2|potassium inwardly-rectifying channel subfamily J, invertebrate;K04999|2|6e-90|332|xtr:549655|potassium inwardly-rectifying channel subfamily J member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005249//voltage-gated potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005249//voltage-gated potassium channel activity GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport 8674063 1409.00 1.215 1.995 0.715432432616565 Up 0.289195614846123 CG42529 CG42529 - - - - 45525 1349.67 196.23 191.6 -0.0344480591916739 Down 0.114780081891428 eIF-4E eukaryotic initiation factor 4E, isoform I K03259|1|8e-119|427|dme:Dmel_CG4035|translation initiation factor eIF-4E GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044430//cytoskeletal part GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death;GO:0006412//translation;GO:0016049//cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0007052//mitotic spindle organization;GO:0007143//female meiosis;GO:0048102//autophagic cell death 14462585 3614.00 0.145 0.255 0.814444346843923 Up 0.106789063531898 CG43691 CG43691, isoform D - - - - 35501 3772.54 39.115 39.125 0.000368787077900314 Up 0.0401862369568089 l(2)NC136 Not3, isoform B K12580|1|0.0|1227|dme:Dmel_CG8426|CCR4-NOT transcription complex subunit 3 GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression 32693 4356.00 0.085 0.055 -0.628031222613042 Down 0.0622440892880729 CG8945 CG8945 K01300|1|6e-48|193|ssc:100155038|carboxypeptidase B2 [EC:3.4.17.20];K01290|2|8e-47|189|dvi:Dvir_GJ16227|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 34421 2404.00 38.415 30.84 -0.31686698840359 Down 0.499042398626337 CG5355 CG5355 K01322|1|0.0|1495|dme:Dmel_CG5355|prolyl oligopeptidase [EC:3.4.21.26] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33392 4819.15 23.635 15.795 -0.581456927611776 Down 0.591335358605204 aop anterior open, isoform E K03211|1|0.0|1078|dme:Dmel_CG3166|ETS translocation variant 6/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0045665//negative regulation of neuron differentiation;GO:0045676//regulation of R7 cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0042480//negative regulation of eye photoreceptor cell development;GO:0007297//ovarian follicle cell migration;GO:0055002//striated muscle cell development;GO:0016192//vesicle-mediated transport;GO:0006350;GO:0001700//embryonic development via the syncytial blastoderm;GO:0060232//delamination;GO:0012502//induction of programmed cell death;GO:0042051//compound eye photoreceptor development;GO:0002682//regulation of immune system process;GO:0000165//MAPK cascade;GO:0045665//negative regulation of neuron differentiation;GO:0045676//regulation of R7 cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0001752//compound eye photoreceptor fate commitment;GO:0042480//negative regulation of eye photoreceptor cell development;GO:0007297//ovarian follicle cell migration;GO:0055002//striated muscle cell development;GO:0016192//vesicle-mediated transport;GO:0006350;GO:0001700//embryonic development via the syncytial blastoderm;GO:0060232//delamination;GO:0012502//induction of programmed cell death;GO:0042051//compound eye photoreceptor development;GO:0002682//regulation of immune system process;GO:0000165//MAPK cascade 31490 3865.96 8.765 12.935 0.561454057925203 Up 0.524798573504161 CG4096 CG4096, isoform C K08622|1|3e-166|441|mdo:100026396|a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-] GO:0031012//extracellular matrix GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 5740490 565.00 0.93 1.205 0.37373052512193 Up 0.148064984810461 CG34210 CG34210 - - - - 33827 636.00 0.255 0.01 -4.6724253419715 Down 0.24085325584467 Vm26Ab vitelline membrane 26Ab, isoform B - GO:0030312//external encapsulating structure GO:0005198//structural molecule activity GO:0001775//cell activation;GO:0003006//developmental process involved in reproduction 48228 1228.00 50.97 51.125 0.00438058481109673 Up 0.0462620525690133 DNaseII deoxyribonuclease II K01158|1|0.0|769|dme:Dmel_CG7780|deoxyribonuclease II [EC:3.1.22.1] - GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters GO:0006259//DNA metabolic process 10178793 471.76 2.15 2.845 0.404091992717121 Up 0.244155329546955 CG42789 CG42789, isoform C - - - - 5740661 1267.00 1.24 1.41 0.185355042011918 Up 0.101406683397173 CG34457 CG34457, isoform B - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33458 2527.48 28.34 33.84 0.255889810201931 Up 0.434420816272619 Hrs hepatocyte growth factor regulated tyrosine kinase substrate, isoform C K12182|1|0.0|725|dse:Dsec_GM18359|hepatocyte growth factor-regulated tyrosine kinase substrate GO:0043234//protein complex;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle;GO:0043234//protein complex;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle;GO:0043234//protein complex;GO:0005768//endosome GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046872//metal ion binding GO:0015031//protein transport;GO:0007297//ovarian follicle cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007041//lysosomal transport;GO:0006996//organelle organization;GO:0008592//regulation of Toll signaling pathway;GO:0016079//synaptic vesicle exocytosis;GO:0015031//protein transport;GO:0007297//ovarian follicle cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007041//lysosomal transport;GO:0006996//organelle organization;GO:0008592//regulation of Toll signaling pathway;GO:0016079//synaptic vesicle exocytosis;GO:0007297//ovarian follicle cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0071842;GO:0007041//lysosomal transport;GO:0008592//regulation of Toll signaling pathway;GO:0016079//synaptic vesicle exocytosis 319043 548.38 7.535 7.56 0.00477872262324872 Up 0.0416061286487914 CG31950 CG31950, isoform B K11086|1|5e-10|63.2|cel:W08E3.1|small nuclear ribonucleoprotein B and B' - - - 38303 2708.00 4.475 4.1 -0.126263772646173 Down 0.138753136970017 CG9004 CG9004 K13100|1|2e-16|88.6|phu:Phum_PHUM091650|pre-mRNA-splicing factor CWC22 GO:0031981//nuclear lumen GO:0005488//binding GO:0044260 8674009 554.00 3.505 5.23 0.577396502236318 Up 0.398989565447101 Sfp65A seminal fluid protein 65A - - - - 4379880 418.00 0.305 0.77 1.33604920313202 Up 0.248018755778629 CG34115 CG34115 - - - - 35255 1156.00 5.115 5.545 0.116453220416381 Up 0.143210936468102 CG10268 CG10268 K13273|1|2e-97|355|dme:Dmel_CG10268|phosphomevalonate kinase [EC:2.7.4.2] GO:0044424//intracellular part GO:0016301//kinase activity GO:0006720//isoprenoid metabolic process;GO:0008203//cholesterol metabolic process 40288 1759.76 35.22 40.94 0.217116193192202 Up 0.404173821159688 cmpy crimpy, isoform D - - GO:0019838//growth factor binding;GO:0019838//growth factor binding GO:0016049//cell growth;GO:0016049//cell growth 4379887 6234.00 0.075 0.15 1 Up 0.0917316074494783 CG34124 CG34124 - - - - 31662 3706.44 34.625 39.705 0.197506624392642 Up 0.380696077136442 CG1677 CG1677, isoform D K13092|1|0.0|1125|dme:Dmel_CG1677|nuclear protein NHN1 - - - 318734 1402.00 11.04 30.165 1.45013541024834 Up 0.724243825122177 CG31436 CG31436 - - - - 32962 1162.39 18.92 21.15 0.160745574667917 Up 0.294049663188482 CG14222 NAA20 ortholog, isoform D K00670|1|2e-99|362|dme:Dmel_CG14222|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0016407//acetyltransferase activity - 33655 1807.00 3.215 3.085 -0.0595482481785294 Down 0.0735041606128649 CG15435 CG15435, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 38403 1444.00 0.08 0.035 -1.1926450779424 Down 0.0725795799762251 CG14960 CG14960 - - - - 31078 4457.00 2.835 2.855 0.010142010420614 Up 0.0432901862369568 CG11409 CG11409, isoform C - - - - 38930 1033.00 25.52 21.395 -0.25435465014138 Down 0.407376832650905 Rab19 Rab19, isoform B K07976|1|1e-119|429|dya:Dyak_GE20724|Rab family, other GO:0044424//intracellular part GO:0032561//guanyl ribonucleotide binding;GO:0004620//phospholipase activity;GO:0005099//Ras GTPase activator activity GO:0035556//intracellular signal transduction;GO:0046907//intracellular transport;GO:0015031//protein transport 59240 865.15 3.915 4.245 0.116752246261998 Up 0.126073173953243 GstD10 glutathione S transferase D10, isoform B K00799|1|8e-123|439|dme:Dmel_CG18548|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups - 35205 1305.00 1 1.53 0.613531652917927 Up 0.228998811253467 CG17564 CG17564 - - - - 3354971 5336.20 21.4 22.59 0.0780734741045752 Up 0.177915731079118 Set1 Set1, isoform I K11422|1|0.0|2962|dme:Dmel_CG40351|histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005488//binding - 19836060 506.00 1.31 1.07 -0.291956015136303 Down 0.13079513934751 39098 1372.00 7.2 6.235 -0.207607346500005 Down 0.241744815744287 CG3434 CG3434 K00773|1|0.0|844|dme:Dmel_CG3434|queuine tRNA-ribosyltransferase [EC:2.4.2.29] - GO:0016763//transferase activity, transferring pentosyl groups;GO:0043169//cation binding GO:0006400//tRNA modification 19835193 1244.00 0.065 0.19 1.54748779530249 Up 0.121186104873861 34006 2185.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG13786 CG13786 - - - - 31582 1670.84 20.455 18.015 -0.183254885461256 Down 0.317824593844935 PpV protein phosphatase V, isoform D K01090|1|0.0|641|dme:Dmel_CG12217|protein phosphatase [EC:3.1.3.16] - - - 35387 2250.00 1.505 1.82 0.274174963438994 Up 0.146975300488707 CG43345 CG43345, isoform C - GO:0044464//cell part;GO:0044464//cell part GO:0050136//NADH dehydrogenase (quinone) activity;GO:0050136//NADH dehydrogenase (quinone) activity - 32937 1110.00 2.555 2.215 -0.206016592382603 Down 0.145456346585656 CG12204 CG12204 - - - - 35246 2370.39 154.1 159.805 0.052445686352836 Up 0.157079646017699 ref(2)P refractory to sigma P, isoform B K01376|1|1e-164|580|dpo:Dpse_GA10271| [EC:3.4.22.-];K10645|2|2e-06|55.1|cin:100170043|E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - 32569 3681.13 19.55 23.02 0.235719225937516 Up 0.387366266015057 vap vacuolar peduncle, isoform F K04352|1|0.0|1785|dya:Dyak_GE15997|Ras GTPase-activating protein 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0005083//small GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005488//binding GO:0030534//adult behavior;GO:0009966//regulation of signal transduction;GO:0030534//adult behavior;GO:0009966//regulation of signal transduction;GO:0030534//adult behavior;GO:0009966//regulation of signal transduction;GO:0030534//adult behavior;GO:0009966//regulation of signal transduction 39168 1979.27 68.175 55.595 -0.294287656788353 Down 0.497655527671378 CG6707 CG6707, isoform C K13084|1|2e-63|243|bfo:BRAFLDRAFT_217178|phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78] - - - 36943 509.00 0.01 0.545 5.76818432477693 Up 0.378384625544842 CG18469 CG18469 - - - - 34294 1594.30 53.59 51.265 -0.0639896210049844 Down 0.169132215031039 und uninitiated, isoform C K01265|1|0.0|838|dsi:Dsim_GD23627|methionyl aminopeptidase [EC:3.4.11.18] - GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process 31312 835.00 0.47 0.945 1.00765357254344 Up 0.240027737419099 CG14269 CG14269, isoform B - - - - 7354413 1089.00 0.285 0.435 0.610053481683987 Up 0.117454761590279 CG42263 CG42263 - - - - 39018 6827.81 17.05 23.97 0.491458169737598 Up 0.560064720644565 orb2 orb2, isoform H K02602|1|1e-53|211|oaa:100078527|oo18 RNA-binding protein - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007613//memory;GO:0007619//courtship behavior;GO:0007613//memory;GO:0007619//courtship behavior;GO:0007613//memory;GO:0007619//courtship behavior;GO:0007613//memory;GO:0007619//courtship behavior 40889 358.00 6.705 16.075 1.26150950031084 Up 0.674382512217673 Mst84Da Male-specific RNA 84Da - - - - 41867 2702.00 3.77 4.045 0.101575179161313 Up 0.108473121120063 CG5038 CG5038 K09667|1|3e-25|117|xtr:553157|polypeptide N-acetylglucosaminyltransferase [EC:2.4.1.-] - - - 41438 1949.59 6.295 5.535 -0.185623060937464 Down 0.213313961167613 mthl5 methuselah-like 5, isoform B K04599|1|0.0|942|dme:Dmel_CG6965|G protein-coupled receptor Mth (Methuselah protein) GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050896//response to stimulus;GO:0010259//multicellular organismal aging 19835875 990.00 0.08 0.135 0.754887502163469 Up 0.0813630960243033 3772685 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 33051 3355.00 0.755 1.01 0.419806743426716 Up 0.147503632281073 RunxB RunxB - - - - 326328 677.00 3.315 4.365 0.396972783516852 Up 0.298507462686567 CG33189 CG33189 - - - - 33647 555.60 22.235 21.575 -0.0434718452851906 Down 0.114482895258222 CG15432 CG15432, isoform C K13120|1|1e-33|142|dme:Dmel_CG15432|protein FAM32A - - - 39609 1581.00 0.5 0.435 -0.200912693925996 Down 0.0688812574296658 CG17173 CG17173 K00738|1|0.0|990|dme:Dmel_CG17173|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145] GO:0044464//cell part GO:0016757//transferase activity, transferring glycosyl groups GO:0044238//primary metabolic process 34316 1099.42 10.975 10.48 -0.0665822228852704 Down 0.129045040285299 CG4594 CG4594, isoform B K13238|1|2e-113|408|dan:Dana_GF15726|3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8] GO:0043231//intracellular membrane-bounded organelle GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds - 40861 5062.97 22.605 13.125 -0.784324494878133 Down 0.636309602430326 sas stranded at second, isoform D K08132|1|9e-06|53.9|mmu:12816|collagen, type XII, alpha GO:0044459//plasma membrane part;GO:0016021//integral to membrane;GO:0044459//plasma membrane part;GO:0016021//integral to membrane GO:0004871//signal transducer activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004871//signal transducer activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0005975//carbohydrate metabolic process;GO:0002164//larval development;GO:0005975//carbohydrate metabolic process;GO:0002164//larval development 34850 5954.08 17.235 21.095 0.291559788852082 Up 0.429929996037512 osp outspread, isoform F - - - - 32664 1669.00 14.725 13.375 -0.138728742541952 Down 0.241216483951922 Sap30 SIN3-associated polypeptide 30, isoform B - GO:0016585//chromatin remodeling complex GO:0043169//cation binding;GO:0003676//nucleic acid binding GO:0000086//G2/M transition of mitotic cell cycle;GO:0010468//regulation of gene expression 37509 1215.00 0.135 0.18 0.415037499278844 Up 0.0678576145819575 CG13500 CG13500 - - - - 33629 588.31 1125.695 1015.795 -0.148206713415366 Down 0.3586712455422 RpL40 ribosomal protein L40, isoform B K02927|1|9e-70|262|cqu:CpipJ_CPIJ002413|large subunit ribosomal protein L40e GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton;GO:0015934//large ribosomal subunit;GO:0031090//organelle membrane;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005488//binding GO:0006351//transcription, DNA-dependent;GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006412//translation;GO:0022613//ribonucleoprotein complex biogenesis;GO:0051276//chromosome organization;GO:0050896//response to stimulus;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006917//induction of apoptosis;GO:0043066//negative regulation of apoptotic process 3772196 5663.00 0.095 0.225 1.24392558288609 Up 0.123563597939506 CG18170 CG18170, isoform B K00164|1|0.0|2237|dme:Dmel_CG33791|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration 39448 11901.00 4.305 4.405 0.0331287815235694 Up 0.0618808611808216 CG32113 CG32113 - - - GO:0033036 59144 1359.00 0.335 0.16 -1.06608919045777 Down 0.144102496367719 CG18748 CG18748, isoform C K01277|1|3e-09|63.5|tca:661730|dipeptidyl-peptidase III [EC:3.4.14.4] - - GO:0050877//neurological system process;GO:0023060;GO:0050877//neurological system process;GO:0023060 36098 856.00 170.965 68.77 -1.31384975572314 Down 0.754424778761062 Prx2540-2 peroxiredoxin 2540-2 K00430|1|2e-128|457|dme:Dmel_CG11765|peroxidase [EC:1.11.1.7] GO:0044444//cytoplasmic part GO:0004601//peroxidase activity GO:0042743//hydrogen peroxide metabolic process;GO:0019725//cellular homeostasis 31086 3416.65 67.785 78.475 0.211267066077318 Up 0.418339717342491 ssx sister-of-Sex-lethal, isoform E K13208|1|5e-44|180|nvi:100119488|ELAV like protein 2/3/4 - - - 40296 1601.00 15.875 19.655 0.308139771877204 Up 0.439968300092458 CG11396 CG11396 - - - - 248102 894.00 18.035 17.455 -0.0471590662348169 Down 0.120756835292564 Gos28 golgi SNARE, 28 kDa K08495|1|5e-116|417|dsi:Dsim_GD19238|golgi SNAP receptor complex member 1 GO:0031985//Golgi cisterna GO:0004871//signal transducer activity GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 39450 4093.00 9.72 9.62 -0.0149194198357387 Down 0.0547483819838859 Hip1 huntingtin interacting protein 1, isoform B K04559|1|1e-121|438|dre:793823|huntingtin interacting protein 1 - GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding - 31625 10621.00 5.945 6.28 0.0790877491459711 Up 0.11306300356624 nonC no-on-and-no-off transient C, isoform B K08873|1|0.0|5793|dme:Dmel_CG32743|PI-3-kinase-related kinase SMG-1 - - - 34896 3669.27 35.175 39.615 0.171496378764354 Up 0.342986395456347 Cul-3 cullin 3, isoform F K03869|1|0.0|1840|dse:Dsec_GM14478|cullin 3 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity;GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity;GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity;GO:0019899//enzyme binding;GO:0019787//small conjugating protein ligase activity GO:0007472//wing disc morphogenesis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0048592//eye morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007472//wing disc morphogenesis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0048592//eye morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007472//wing disc morphogenesis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0048592//eye morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007472//wing disc morphogenesis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0048592//eye morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 31543 7096.30 8.185 9.14 0.159211748583916 Up 0.222989037115308 raptor raptor, isoform C K07204|1|0.0|2772|dme:Dmel_CG4320|regulatory associated protein of mTOR - - - 59247 2232.00 0.07 0.245 1.8073549220576 Up 0.153909655263505 zwilch zwilch K11579|1|0.0|1248|dme:Dmel_CG18729|protein zwilch GO:0000775//chromosome, centromeric region - GO:0045841//negative regulation of mitotic metaphase/anaphase transition 19835670 1334.00 0.035 0.43 3.61890983264449 Up 0.275855237088892 31630 1576.00 8.6 8.37 -0.0391090370391164 Down 0.084070796460177 Cht11 Cht11 K01183|1|0.0|837|dme:Dmel_CG3044|chitinase [EC:3.2.1.14] - - - 318147 2676.00 0.41 0.45 0.134301091711591 Up 0.0577532690529653 CG32668 CG32668 - - - - 39336 1360.38 181.565 191.845 0.0794550415203653 Up 0.220182274468366 CG5946 CG5946, isoform G K00326|1|4e-174|610|dsi:Dsim_GD12773|cytochrome-b5 reductase [EC:1.6.2.2] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0002118//aggressive behavior;GO:0008152//metabolic process;GO:0002118//aggressive behavior;GO:0008152//metabolic process;GO:0002118//aggressive behavior;GO:0008152//metabolic process;GO:0002118//aggressive behavior;GO:0008152//metabolic process;GO:0002118//aggressive behavior;GO:0008152//metabolic process;GO:0002118//aggressive behavior 41235 2454.00 1.11 1.09 -0.0262315415731797 Down 0.0445449742438251 nerfin-2 nervous fingers 2, isoform B K09228|1|8e-10|65.9|mcc:720058|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 31200 1763.94 80.46 105.25 0.387476590215491 Up 0.581032888654075 msta msta, isoform D K11848|1|3e-14|80.1|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15];K11426|2|1e-13|78.2|rno:498295|SET and MYND domain-containing protein - - - 8674013 590.00 0.345 0.235 -0.553935605100532 Down 0.101142517500991 CG42493 CG42493 - - - - 261617 383.00 29.75 33.41 0.167390314252302 Up 0.334401003830405 CG31777 CG31777 - - GO:0004866//endopeptidase inhibitor activity - 32132 2248.60 58.535 63.82 0.124709091146604 Up 0.281898031964073 CkIIbeta casein kinase II beta subunit, isoform K K03115|1|2e-131|468|dsi:Dsim_GD17050|casein kinase 2, beta polypeptide GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity;GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity;GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity;GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity;GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity;GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0007562//eclosion;GO:0006464//cellular protein modification process;GO:0007420//brain development;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007562//eclosion;GO:0006464//cellular protein modification process;GO:0007420//brain development;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007562//eclosion;GO:0006464//cellular protein modification process;GO:0007420//brain development;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007562//eclosion;GO:0006464//cellular protein modification process;GO:0007420//brain development;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007562//eclosion;GO:0006464//cellular protein modification process;GO:0007420//brain development;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007562//eclosion;GO:0006464//cellular protein modification process;GO:0007420//brain development;GO:0048511//rhythmic process;GO:0007626//locomotory behavior 3771768 144.00 0.435 0.455 0.0648511443499679 Up 0.0455355963545106 38259 11334.00 9.59 12.25 0.353179028871802 Up 0.418537841764628 CG42863 mauve K07295|1|2e-25|120|dpe:Dper_GL19043|nuclear receptor subfamily 2 group A - - - 33836 1776.58 18.765 22.285 0.248028670725678 Up 0.395093118478404 ifc infertile crescent, isoform B K04712|1|0.0|675|dme:Dmel_CG9078|sphingolipid delta-4 desaturase [EC:1.14.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016215 GO:0006631//fatty acid metabolic process;GO:0048232//male gamete generation 31237 1395.97 26.105 28.88 0.145744583539243 Up 0.299332981112138 CG13760 CG13760, isoform D K02149|1|8e-17|88.6|dse:Dsec_GM18874|V-type H+-transporting ATPase subunit D [EC:3.6.3.14] - - - 36252 1232.31 201.255 210.325 0.0635957181427507 Up 0.180821555937129 wal walrus, isoform B K03522|1|2e-170|598|dme:Dmel_CG8996|electron transfer flavoprotein alpha subunit GO:0031980;GO:0031980 GO:0030554//adenyl nucleotide binding;GO:0030554//adenyl nucleotide binding GO:0007439//ectodermal digestive tract development;GO:0048598//embryonic morphogenesis;GO:0060541//respiratory system development;GO:0006091//generation of precursor metabolites and energy;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007439//ectodermal digestive tract development;GO:0048598//embryonic morphogenesis;GO:0060541//respiratory system development;GO:0006091//generation of precursor metabolites and energy;GO:0001700//embryonic development via the syncytial blastoderm 33846 906.00 2.435 2.76 0.180746494695827 Up 0.136804913485669 CG9117 CG9117 - - GO:0003824//catalytic activity - 10178840 2131.00 107.555 94.92 -0.180290588456618 Down 0.38647470611544 CG42837 CG42837 K10105|1|0.0|648|dpo:Dpse_GA21085|lipoyltransferase 1 [EC:6.-.-.-] - GO:0003824//catalytic activity GO:0018065//protein-cofactor linkage 45827 1298.12 263.5 244.04 -0.110685326074309 Down 0.282525425967508 bic bicaudal, isoform B K01527|1|4e-66|252|dsi:Dsim_GD10924|nascent polypeptide-associated complex subunit beta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton - GO:0044087;GO:0044087 33061 741.00 0.43 0.36 -0.256339753259786 Down 0.0762448817857615 CG15452 CG15452 - GO:0005911//cell-cell junction - - 38758 924.00 27.11 27.77 0.0347020639811341 Up 0.101142517500991 CG10075 CG10075 - - - - 42388 2271.00 17.07 14.47 -0.238398136496014 Down 0.362435609562805 CG4433 CG4433, isoform D K03434|1|0.0|666|dme:Dmel_CG4433|N-acetylglucosaminylphosphatidylinositol deacetylase [EC:3.5.1.89] - - - 44451 3688.06 10.96 11.225 0.0344676466679827 Up 0.0834434024567428 ear ENL/AF9-related, isoform C K11341|1|3e-13|78.2|bfo:BRAFLDRAFT_113729|YEATS domain-containing protein 4 GO:0005667//transcription factor complex GO:0003702//RNA polymerase II transcription factor activity GO:0006351//transcription, DNA-dependent 35682 2006.00 4.47 4.89 0.129559633768916 Up 0.145522388059701 az2 az2 K09228|1|9e-30|132|api:100159445|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 12798325 482.00 37.35 61.24 0.713366039823188 Up 0.670122837141725 CG43103 CG43103 - - - - 48448 1516.14 83.245 85.155 0.0327276211030072 Up 0.11144498745212 CkIIalpha casein kinase IIalpha, isoform G K03097|1|0.0|652|dya:Dyak_GE22657|casein kinase 2, alpha polypeptide [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0001654//eye development;GO:0006935//chemotaxis;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0006935//chemotaxis;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0001654//eye development;GO:0006935//chemotaxis;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process 40844 1024.78 116.97 152.245 0.380256287636781 Up 0.583212257297583 CG1943 CG1943, isoform D - - - - 43382 2255.00 3.44 4.02 0.22478693647683 Up 0.193171311583675 CG12413 CG12413 K02519|1|0.0|1303|dme:Dmel_CG12413|translation initiation factor IF-2 GO:0044464//cell part GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006412//translation 35209 1147.00 1.705 2.125 0.317691102000892 Up 0.181779157310791 CG17349 CG17349 - - - - 246409 1387.00 0.115 0.125 0.120294233717712 Up 0.0441487253995509 CG30037 CG30037 K07819|1|3e-124|445|der:Dere_GG22617|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process 41137 1156.00 22.42 21.91 -0.0331967938152044 Down 0.09708096684718 CG8149 CG8149 K09534|1|5e-07|55.5|ptr:467031|DnaJ homolog subfamily C member 14 - GO:0005488//binding GO:0012501//programmed cell death;GO:0007450//dorsal/ventral pattern formation, imaginal disc 40153 6218.94 5.165 4.015 -0.363368361347745 Down 0.306003169990754 CG42637 CG42637, isoform C K12323|1|0.0|781|phu:Phum_PHUM100000|atrial natriuretic peptide receptor A [EC:4.6.1.2];K01769|2|0.0|763|tca:657050|guanylate cyclase, other [EC:4.6.1.2] - GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0032559 GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006464//cellular protein modification process;GO:0009124//nucleoside monophosphate biosynthetic process 3346188 520.00 1.405 2.185 0.637063149279672 Up 0.281633866067891 Vkor Vitamin-K epoxide reductase K05357|1|1e-63|241|dme:Dmel_CG33544|vitamin-K-epoxide reductase (warfarin-sensitive) [EC:1.1.4.1] - GO:0016491//oxidoreductase activity GO:0006766//vitamin metabolic process 33385 1510.72 2.68 8.09 1.59390670197221 Up 0.642286355831462 CG4259 CG4259, isoform B K01310|1|1e-18|94.0|mmu:66473|chymotrypsin [EC:3.4.21.1];K09632|3|3e-18|92.4|dre:447843|chymotrypsin-like protease [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38125 486.00 4.88 0.395 -3.62695658938578 Down 0.685840707964602 LysB lysozyme B, isoform B K01185|1|2e-75|280|dme:Dmel_CG1179|lysozyme [EC:3.2.1.17];K01183|2|2e-75|280|dme:Dmel_CG9118|chitinase [EC:3.2.1.14];K13915|5|5e-70|262|dwi:Dwil_GK12154|lysozyme C [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 41457 2236.00 57.975 35.785 -0.696075935216631 Down 0.666061286487914 Ect3 Ectoderm-expressed 3 K12309|1|0.0|1222|dme:Dmel_CG3132|beta-galactosidase [EC:3.2.1.23] GO:0000323//lytic vacuole GO:0043167//ion binding;GO:0015925 GO:0048102//autophagic cell death;GO:0044238//primary metabolic process 35001 4521.00 2.305 2.63 0.190296048862965 Up 0.140734381191388 glu gluon K06675|1|0.0|2366|dme:Dmel_CG11397|structural maintenance of chromosome 4 GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0044425//membrane part;GO:0000793//condensed chromosome GO:0003676//nucleic acid binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0032559 GO:0000070//mitotic sister chromatid segregation;GO:0007399//nervous system development 19834805 1215.00 0.1 0.075 -0.415037499278844 Down 0.0547483819838859 19836135 778.00 5.205 6.16 0.243032187395484 Up 0.250561352529388 19834719 505.00 0.41 0.275 -0.576192291093424 Down 0.113723418306697 33805 3224.74 14.61 16.14 0.143684400474282 Up 0.250363228107251 CG11030 CG11030, isoform B - - - - 32242 683.01 31.125 37.1 0.25334534966536 Up 0.431052701096288 mRpL49 mitochondrial ribosomal protein L49, isoform B - GO:0000315//organellar large ribosomal subunit GO:0008135//translation factor activity, nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation 36368 2889.11 14.36 15.595 0.119027803551101 Up 0.219191652357681 Dh44-R2 diuretic hormone 44 receptor 2, isoform B K04578|1|1e-128|460|aga:AgaP_AGAP005464|corticotropin releasing hormone receptor 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0005179//hormone activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0005179//hormone activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 40050 916.00 0.095 0.05 -0.925999418556223 Down 0.0768722757891956 CG6865 CG6865, isoform B K09640|1|3e-46|185|tgu:100229086|transmembrane protease, serine 9 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39933 1396.00 35.37 54.485 0.623332884168161 Up 0.646149782063136 Mip myoinhibiting peptide precursor - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway 3346160 2994.00 25.23 29.895 0.244764004583914 Up 0.40813630960243 dpr4 dpr4 K06765|1|3e-06|54.7|mmu:13176|deleted in colorectal carcinoma - - - 43393 2219.86 1.55 1.13 -0.455945442859049 Down 0.1939307885352 AR-2 allatostatin A receptor 2, isoform C K04233|1|1e-64|247|dya:Dyak_GE16306|galanin receptor, invertebrate GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 3346149 2221.00 0.04 0.12 1.58496250072116 Up 0.101736890767402 upd3 unpaired 3 - - GO:0005102//receptor binding GO:0006959//humoral immune response;GO:0007243//intracellular protein kinase cascade 2768661 1437.83 22.01 24.13 0.132668770324194 Up 0.263175274072117 Fer1 48 related 1, isoform B K09073|1|9e-31|134|spu:581998|pancreas-specific transcription factor 1a GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity GO:0048731;GO:0010468//regulation of gene expression;GO:0010556;GO:0006350 40716 1592.00 17.665 19.1 0.112678889032459 Up 0.218960507198521 CG2051 CG2051, isoform B K11303|1|0.0|818|dme:Dmel_CG2051|histone acetyltransferase 1 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004468//lysine N-acetyltransferase activity GO:0006342//chromatin silencing;GO:0016570//histone modification 42438 1562.00 36.785 36.805 0.000784179957281842 Up 0.0416061286487914 Sep2 septin 2, isoform B K04557|1|6e-71|268|xla:779425|peanut-like protein 1 (cell division control related protein 1) GO:0032156;GO:0045171//intercellular bridge;GO:0015630//microtubule cytoskeleton GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0007275//multicellular organismal development;GO:0051301//cell division 246575 1399.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG30375 CG30375 K09637|1|1e-31|137|mdo:100025330|transmembrane protease, serine 6 [EC:3.4.21.-];K09640|2|2e-31|136|ecb:100146332|transmembrane protease, serine 9 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41414 887.00 0.925 1.615 0.804008894177613 Up 0.276977942147669 I-t inhibitor-t - - GO:0019212//phosphatase inhibitor activity GO:0006470//protein dephosphorylation 34916 942.00 0.01 0.145 3.85798099512757 Up 0.163848897107383 CG15253 CG15253 K08076|1|1e-38|159|cel:F39D8.4|astacin [EC:3.4.24.21];K01395|2|2e-37|155|cin:100181769|meprin A, alpha [EC:3.4.24.18];K08606|5|8e-36|150|ecb:100052389|meprin A, beta [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 3346142 934.51 0.735 0.815 0.149055809394713 Up 0.0742636375643904 CG13376 CG13376, isoform D - - - - 38698 1129.98 26.97 19.55 -0.464186914040889 Down 0.55745608241976 loj logjam, isoform F K01529|1|4e-07|55.8|mcc:709884| [EC:3.6.1.-] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization 34099 10022.00 6.805 6.335 -0.103250542363185 Down 0.141493858142914 CG7466 CG7466, isoform C K05637|1|2e-19|100|gga:374016|laminin, alpha 1 GO:0031224//intrinsic to membrane GO:0046872//metal ion binding - 53473 3037.25 42.935 25.205 -0.768444237426699 Down 0.668306696605468 SP1029 SP1029, isoform E K11140|1|0.0|1838|dme:Dmel_CG11956|aminopeptidase N [EC:3.4.11.2] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 32474 2546.82 5.285 5.79 0.131659876606554 Up 0.158103288865407 CG6294 CG6294, isoform B K08051|1|4e-78|293|dpo:Dpse_GA19499|pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 GO:0044424//intracellular part GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0006869//lipid transport 38364 1832.97 15.79 15.765 -0.00228600117690229 Down 0.0416061286487914 CG1271 CG1271, isoform D K00864|1|1e-39|165|ame:551041|glycerol kinase [EC:2.7.1.30] - GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process;GO:0006071//glycerol metabolic process 35527 2171.18 23.27 19.66 -0.243207889064768 Down 0.390932505613525 Pngl PNGase-like, isoform C K01456|1|0.0|1222|dme:Dmel_CG7865|peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0003677//DNA binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0003677//DNA binding GO:0009057//macromolecule catabolic process;GO:0006281//DNA repair;GO:0009057//macromolecule catabolic process;GO:0006281//DNA repair 39491 3365.00 12.48 14.375 0.203944021856852 Up 0.309404305904108 trn tartan, isoform B K13023|1|4e-37|157|oaa:100081004|carboxypeptidase N regulatory subunit GO:0005635//nuclear envelope;GO:0016020//membrane GO:0008565//protein transporter activity;GO:0005488//binding GO:0007411//axon guidance;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0007270//neuron-neuron synaptic transmission;GO:0006887//exocytosis;GO:0035146 40192 2712.00 1.695 2.03 0.260194454048833 Up 0.152324659886409 CG14183 CG14183 K00665|1|3e-52|207|tca:658978|fatty acid synthase, animal type [EC:2.3.1.85];K13254|2|1e-11|72.4|isc:IscW_ISCW020482|spastin [EC:3.6.4.3];K07767|4|6e-11|70.1|phu:Phum_PHUM080400|microtubule-severing ATPase [EC:3.6.4.3] - GO:0016462//pyrophosphatase activity;GO:0032559 - 31440 1157.00 0.335 0.52 0.63435052768332 Up 0.129177123233391 CG17764 CG17764 - GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex - GO:0000377 33444 819.69 27.9 24.49 -0.188072348152572 Down 0.349029190331528 Arpc5 Actin-related protein 2/3 complex, subunit 5, isoform B K05754|1|7e-81|300|dme:Dmel_CG9881|actin related protein 2/3 complex, subunit 5 GO:0043232;GO:0031252//cell leading edge - GO:0006909//phagocytosis;GO:0008064//regulation of actin polymerization or depolymerization 43092 1860.28 121.435 120.84 -0.00708620596529818 Down 0.0672302205785233 Ssadh succinic semialdehyde dehydrogenase, isoform E K00139|1|0.0|979|dme:Dmel_CG4685|succinate-semialdehyde dehydrogenase [EC:1.2.1.24] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009448//gamma-aminobutyric acid metabolic process 192509 3414.67 29.15 28.935 -0.0106802393175991 Down 0.0612864879144102 CG12084 CG12084, isoform B K10350|1|0.0|1556|dme:Dmel_CG12084|Zyg-11 protein homolog - - - 53541 779.00 7.355 7.18 -0.0347414974317786 Down 0.0722493726059966 lectin-30A lectin-30A K05328|1|3e-10|65.5|dan:Dana_GF15877|transient receptor potential cation channel subfamily C, invertebrate;K06560|2|1e-06|53.1|hmg:100206932|mannose receptor, C type - - - 19834836 864.00 4.915 4.91 -0.00146839202588731 Down 0.0382380134724607 31598 3103.00 10.47 8.51 -0.299030405244846 Down 0.362237485140668 l(1)G0148 lethal (1) G0148, isoform B K02214|1|0.0|1157|dme:Dmel_CG32742|cell division control protein 7 [EC:2.7.11.1] - - - 32214 1203.37 0.44 0.815 0.88929653559378 Up 0.204992735437855 CG15728 CG15728, isoform B - - - - 36830 1350.34 12.395 15.38 0.311297231875104 Up 0.416325452384097 Nup62 nucleoporin 62kD, isoform B - GO:0005635//nuclear envelope GO:0005198//structural molecule activity GO:0006909//phagocytosis;GO:0002524 33868 5629.00 0.345 0.665 0.94675797872302 Up 0.191652357680623 CG13991 CG13991 - - - - 34847 2733.83 33.625 31.54 -0.0923516075408387 Down 0.211068551050059 noc no ocelli, isoform B - - GO:0030528//transcription regulator activity;GO:0005488//binding GO:0060541//respiratory system development;GO:0007444//imaginal disc development;GO:0002118//aggressive behavior;GO:0006355//regulation of transcription, DNA-dependent 31198 2939.58 21.695 11.475 -0.918868432515572 Down 0.655923920221899 Mct1 monocarboxylate transporter 1, isoform B K11810|1|4e-33|144|bfo:BRAFLDRAFT_210112|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 12;K08181|3|4e-33|144|gga:419809|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 4;K08190|5|3e-32|140|mdo:100014050|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14 - - - 19835611 3635.00 0.015 0.09 2.58496250072116 Up 0.11075155197464 43670 2777.01 3.41 3.295 -0.0494932740161209 Down 0.0696737551182142 CanA1 calcineurin A1, isoform D K04348|1|0.0|999|dme:Dmel_CG1455|protein phosphatase 3, catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0030136//clathrin-coated vesicle GO:0004722//protein serine/threonine phosphatase activity GO:0006810//transport;GO:0001505//regulation of neurotransmitter levels;GO:0006464//cellular protein modification process 40830 2514.00 0.175 0.7 2 Up 0.281402720908731 bcd bicoid, isoform G K09362|1|3e-157|548|dsi:Dsim_GD19520|homeo domain only family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0030528//transcription regulator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0030528//transcription regulator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0006412//translation;GO:0007292//female gamete generation;GO:0007365//periodic partitioning;GO:0010551;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0006412//translation;GO:0007292//female gamete generation;GO:0007365//periodic partitioning;GO:0010551;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0006412//translation;GO:0007292//female gamete generation;GO:0007365//periodic partitioning;GO:0010551;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0006412//translation;GO:0007292//female gamete generation;GO:0007365//periodic partitioning;GO:0010551;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0006412//translation;GO:0007292//female gamete generation;GO:0007365//periodic partitioning;GO:0010551 34986 581.00 2.495 2.33 -0.0987098606829804 Down 0.0880002641658962 CG5968 CG5968, isoform B - - - - 32302 1035.00 4.915 10.635 1.11355671162009 Up 0.62012944128913 CG34324 CG34324 - - GO:0022857//transmembrane transporter activity;GO:0030247//polysaccharide binding;GO:0017111//nucleoside-triphosphatase activity GO:0051234//establishment of localization;GO:0006022 41737 13344.56 12.165 13.25 0.123256039399495 Up 0.209648659358077 trx trithorax, isoform E K09186|1|0.0|5185|dme:Dmel_CG8651|myeloid/lymphoid or mixed-lineage leukemia protein 1/4 - - - 19835548 3221.00 2.885 3.655 0.341300087306955 Up 0.25069343547748 - CG45068 - - - - 19835955 201.00 0.495 0.01 -5.62935662007961 Down 0.356888125742967 40984 1666.05 0.85 0.895 0.0744248411265544 Up 0.0525359926033549 CG11693 CG11693, isoform B - - - - 246424 1327.52 0.52 0.64 0.299560281858908 Up 0.0972460705322943 CG30058 CG30058, isoform B - - - - 41480 1393.00 4.37 5.255 0.26605748446158 Up 0.250033020737023 CG4860 CG4860 K00249|1|0.0|784|dme:Dmel_CG4860|acyl-CoA dehydrogenase [EC:1.3.99.3];K00248|2|9e-137|486|aag:AaeL_AAEL004137|butyryl-CoA dehydrogenase [EC:1.3.99.2] - - - 38796 739.00 23.665 27.94 0.2395770986711 Up 0.402489763571523 mRpL50 mitochondrial ribosomal protein L50 - GO:0000315//organellar large ribosomal subunit - - 40075 1856.00 4.105 2.92 -0.491413852897788 Down 0.329943204332321 CG18136 CG18136 K11426|1|7e-19|95.9|cin:778761|SET and MYND domain-containing protein;K11848|3|4e-13|76.6|dsi:Dsim_GD11032|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15] GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006350 31280 2687.00 0.02 0.01 -1 Down 0.0497292299564126 CG32793 CG32793 - - - - 40503 704.00 0.01 0.265 4.7279204545632 Up 0.2511557257958 CG13239 CG13239 - - - - 12798339 490.06 0.255 0.01 -4.6724253419715 Down 0.24085325584467 CG43070 CG43070, isoform B - - - - 32056 1070.41 13.045 9.39 -0.474299881163677 Down 0.489961695945054 rtv retroactive, isoform D - - - GO:0006023;GO:0035151//regulation of tube size, open tracheal system 19835677 549.00 0.01 0.415 5.37503943134692 Up 0.323239994716682 - CG44259 - - - - 10178784 325.00 0.545 0.155 -1.81398801439005 Down 0.237650244353454 CG42716 CG42716 - - - - 38941 1051.00 13.065 12.015 -0.120870476190154 Down 0.206610751551975 Pex2 peroxin 2 K06664|1|2e-164|578|dme:Dmel_CG7081|peroxin-2 GO:0044439 GO:0046914//transition metal ion binding GO:0006996//organelle organization 39327 442.00 0.85 1.905 1.16425625135562 Up 0.360850614185709 Tim13 Tim13 K10836|1|1e-47|187|dme:Dmel_CG11611|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 32483 4937.68 13.075 9.92 -0.398398920747429 Down 0.454266279223352 Gmap golgi microtubule-associated protein, isoform C K04514|1|6e-07|57.8|nvi:100119770|Rho-associated, coiled-coil containing protein kinase [EC:2.7.11.1] - - - 3355124 1029.76 1506.985 1407.835 -0.0981867986837712 Down 0.267302866199974 RpL5 ribosomal protein L5, isoform H K02932|1|1e-175|600|dse:Dsec_GM26730|large subunit ribosomal protein L5e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0019843//rRNA binding;GO:0005198//structural molecule activity;GO:0019843//rRNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 8673983 624.97 2.375 1.72 -0.465518948516212 Down 0.245971470083212 Sfp53D seminal fluid protein 53D, isoform B - - - - 35979 1701.40 14.42 16.91 0.229805495169161 Up 0.352826575089156 CG1888 CG1888, isoform D - - - - 42937 3166.52 6.62 7.225 0.126166370580823 Up 0.171245542200502 CG6695 CG6695, isoform B K13168|1|6e-156|551|dme:Dmel_CG6695|splicing factor, arginine/serine-rich 16 - - - 34180 1454.00 2.86 2.845 -0.0075864944718076 Down 0.0432901862369568 CG13088 CG13088 - - - - 2768715 1649.00 8.3 6.725 -0.303577068790301 Down 0.333377360982697 CheB42c chemosensory protein B 42c - GO:0044421//extracellular region part GO:0005261//cation channel activity GO:0030001//metal ion transport;GO:0009593//detection of chemical stimulus 42650 553.00 2.705 3.865 0.514839820098032 Up 0.327796856425835 CG7045 CG7045 K09272|1|7e-13|73.2|cfa:475970|structure-specific recognition protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding - 5740793 1100.62 0.69 1.04 0.591915261362923 Up 0.182769779421477 CG34312 CG34312, isoform C - - - - 19835693 494.00 1.245 1.4 0.169281084876886 Up 0.0974441949544314 39895 1720.00 0.5 0.19 -1.39592867633114 Down 0.201558578787479 CG11905 CG11905, isoform L - - - - 42031 1103.00 2.525 6.355 1.3316087373658 Up 0.585160480781931 CG14907 CG14907 - - - - 7354470 4354.65 16.87 20.21 0.26060934809217 Up 0.39723946638489 CG42402 CG42402, isoform E K03681|1|3e-07|57.4|mcc:708681|exosome complex component RRP40;K04594|2|3e-06|53.9|oaa:100079263|latrophilin 3;K04592|3|3e-06|53.9|oaa:100088198|latrophilin 1 - GO:0030246//carbohydrate binding - 35702 1479.00 12.925 11.69 -0.144889350670641 Down 0.234348170651169 CG17985 CG17985 - GO:0044424//intracellular part GO:0016462//pyrophosphatase activity;GO:0032559 GO:0009057//macromolecule catabolic process 42060 1895.00 13.17 12.97 -0.0220768660048148 Down 0.0696077136441685 ns1 nucleostemin ortholog 1 - - - - 33134 1210.00 6.41 6.855 0.0968323091604849 Up 0.13832386738872 CG14618 CG14618 - - - - 19835423 641.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 35147 3239.81 7.845 8.72 0.152554687808829 Up 0.209945845991283 tup tailup, isoform C K09370|1|1e-58|228|dre:30147|insulin gene enhancer protein ISL GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007411//axon guidance;GO:0001894//tissue homeostasis;GO:0006355//regulation of transcription, DNA-dependent;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006928//cellular component movement;GO:0001708//cell fate specification;GO:0007411//axon guidance;GO:0001894//tissue homeostasis;GO:0006355//regulation of transcription, DNA-dependent;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006928//cellular component movement;GO:0001708//cell fate specification 35912 1288.00 0.415 0.465 0.164119379761107 Up 0.0640932505613525 CG8197 CG8197, isoform B K12800|1|4e-07|56.2|dre:561595|NACHT, LRR and PYD domains-containing protein 3 - - - 34708 3809.00 25.72 26.55 0.0458212183635687 Up 0.131521595562013 Sir2 Sir2 K11411|1|0.0|1387|dme:Dmel_CG5216|NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0004407//histone deacetylase activity;GO:0051287//NAD binding GO:0006476//protein deacetylation;GO:0016458//gene silencing;GO:0010259//multicellular organismal aging;GO:0006915//apoptotic process;GO:0016573//histone acetylation;GO:0031667//response to nutrient levels 19835648 424.00 6.055 6.655 0.136311706217563 Up 0.17504292695813 37901 1766.00 0.345 0.17 -1.02106161552783 Down 0.139776779817726 CG4563 CG4563 K01904|1|6e-38|159|cel:F11A3.1|4-coumarate--CoA ligase [EC:6.2.1.12];K01896|5|9e-23|108|mmu:20216|medium-chain acyl-CoA synthetase [EC:6.2.1.2] - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 39091 2055.00 7.68 6.84 -0.167109985835258 Down 0.215757495707304 Nf-YA nuclear factor Y-box A K08064|1|3e-23|110|isc:IscW_ISCW017122|nuclear transcription factor Y, alpha GO:0005667//transcription factor complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006351//transcription, DNA-dependent 19834935 5017.19 2.24 3.235 0.530266979934904 Up 0.306894729890371 38141 1682.95 12.715 5.91 -1.10530142651257 Down 0.637696473385286 CG9134 CG9134, isoform C K06560|1|9e-17|87.4|nve:NEMVE_v1g238062|mannose receptor, C type - GO:0030246//carbohydrate binding;GO:0030246//carbohydrate binding;GO:0030246//carbohydrate binding - 38454 543.00 24.75 26.45 0.0958391971470538 Up 0.216847180029058 CG14977 CG14977, isoform B - - - - 39748 3534.00 26.47 23.185 -0.191166468120873 Down 0.346651697265883 CG5830 CG5830, isoform B K01090|1|2e-148|527|dme:Dmel_CG5830|protein phosphatase [EC:3.1.3.16] - GO:0042578//phosphoric ester hydrolase activity - 35958 3461.00 0.055 1.955 5.15159317867005 Up 0.595859199577335 Or45a odorant receptor 45a K08471|1|0.0|726|dme:Dmel_CG1978|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0007166//cell surface receptor signaling pathway;GO:0023060 31066 2579.00 1.66 0.83 -1 Down 0.318418967111346 CG14625 CG14625 - - - - 33701 3950.00 0.295 0.435 0.560300446486887 Up 0.112897899881125 Sgs1 salivary gland secretion 1 K10876|1|6e-07|57.4|phu:Phum_PHUM576960|RAD54-like protein 2 [EC:3.6.1.-] - - - 42381 410.00 1.79 1.865 0.0592160429909816 Up 0.0625412759212786 CG4783 CG4783, isoform B - - - - 42460 6073.60 54.05 63.55 0.233597507270309 Up 0.434883106590939 Syp syncrip, isoform R K13161|1|1e-144|514|gga:419570|heterogeneous nuclear ribonucleoprotein R GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377 3772280 1257.09 6.44 8.2 0.348563221390829 Up 0.362930920618148 LSm-4 like Sm protein 4, isoform C K12623|1|1e-69|264|dsi:Dsim_GD22262|U6 snRNA-associated Sm-like protein LSm4 - - - 31933 2804.61 32.005 25.635 -0.320182410868379 Down 0.488574824990094 CG32694 CG32694, isoform H - - - - 40427 1410.00 3.94 3.93 -0.00366631719776974 Down 0.0401862369568089 CG7370 CG7370 - - - - 42426 1849.32 68.74 63.75 -0.108724509738715 Down 0.265816933033945 CG4288 CG4288, isoform B K08193|1|0.0|998|dme:Dmel_CG4288|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport;GO:0006810//transport 19835702 499.00 0.095 0.095 0 - 0.0382380134724607 38659 1817.00 0.01 1.395 7.12412131182919 Up 0.577796856425835 CG18586 CG18586, isoform C K01904|1|1e-41|171|spu:581911|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 37244 1166.00 21.045 18.645 -0.174688712567414 Down 0.308545766741514 TBCB tubulin-binding cofactor B K10392|1|2e-10|66.6|tgu:100221357|kinesin family member 1/13/14 - - - 33940 1808.00 1.31 2.02 0.624788481214344 Up 0.267236824725928 CG11327 CG11327 - - - - 32714 708.00 0.065 0.01 -2.70043971814109 Down 0.09708096684718 CG10597 CG10597 - - - - 36396 2842.97 26.595 33.74 0.343304936667721 Up 0.507330603619073 CG42708 CG42708, isoform K K01425|1|0.0|1263|dme:Dmel_CG8772|glutaminase [EC:3.5.1.2] GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory;GO:0009064//glutamine family amino acid metabolic process;GO:0007611//learning or memory 35117 2631.00 0.055 0.125 1.18442457113743 Up 0.0921608770307753 CG43338 CG43338, isoform B K10352|1|7e-12|73.2|mcc:717943|myosin heavy chain;K12478|2|1e-11|72.0|oaa:100079644|early endosome antigen 1 - - - 34688 5788.00 12.155 15.995 0.396071099086945 Up 0.476687359661868 kek1 kekkon-1 K07523|1|1e-75|285|dme:Dmel_CG4192|netrin-G1 ligand;K06838|2|5e-24|114|ecb:100061086|slit 1 - GO:0005488//binding - 19835983 1477.00 0.13 0.185 0.509013647487857 Up 0.0744617619865275 37537 2021.72 91.96 75.8 -0.278808617659726 Down 0.496400739664509 Swim secreted Wg-interacting molecule, isoform B K01363|1|9e-43|175|isc:IscW_ISCW000078|cathepsin B [EC:3.4.22.1] GO:0030312//external encapsulating structure;GO:0030312//external encapsulating structure GO:0001871;GO:0004175//endopeptidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0001871;GO:0004175//endopeptidase activity;GO:0004888//transmembrane signaling receptor activity GO:0019538//protein metabolic process;GO:0002376//immune system process;GO:0019538//protein metabolic process;GO:0002376//immune system process 32849 2421.02 22.9 20.66 -0.148507344119247 Down 0.285695416721701 wgn wengen, isoform B K12484|1|1e-33|145|dsi:Dsim_GD15625|Rab11 family-interacting protein 1/2/5 GO:0016021//integral to membrane GO:0005488//binding;GO:0005035//death receptor activity GO:0023033;GO:0012501//programmed cell death 5740668 6896.70 5.95 5.925 -0.00607451440968407 Down 0.0432901862369568 CG34347 CG34347, isoform E K06107|1|8e-72|273|mdo:100015377|erythrocyte membrane protein band 4.1 GO:0043232;GO:0043232 - - 31671 1091.00 1.73 3.1 0.841496177637513 Up 0.385748249900938 CG1999 CG1999 - - - - 3772343 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 37056 847.02 16.99 11.915 -0.51190690099395 Down 0.536322810725135 CG14495 CG14495, isoform B - - - - 34938 1373.00 0.17 0.32 0.91253715874966 Up 0.126238277638357 CG31821 CG31821, isoform B K09646|1|3e-100|365|dvi:Dvir_GJ13240|serine carboxypeptidase 1 [EC:3.4.16.-] - GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process 33949 1765.00 0.325 0.495 0.606988807051155 Up 0.125313697001717 CG11322 CG11322 - - - - 40540 2182.00 81.685 77.785 -0.0705792035392348 Down 0.192378813895126 CG9780 CG9780 - - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 40708 1190.00 18.08 16.865 -0.100362359397061 Down 0.199511293092062 CG1236 CG1236 K00015|1|2e-74|279|hsa:9380|glyoxylate reductase [EC:1.1.1.26];K00049|1|2e-74|279|hsa:9380|glyoxylate reductase (NADP+) [EC:1.1.1.79];K00058|4|2e-24|113|nvi:100116297|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] - GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding - 41343 517.88 1330.915 1321.825 -0.00988724809079394 Down 0.0711596882842425 RpS25 ribosomal protein S25, isoform B K02975|1|7e-41|166|dvi:Dvir_GJ10295|small subunit ribosomal protein S25e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 12798458 818.00 0.195 0.165 -0.241008099503795 Down 0.0577532690529653 CG43312 CG43312 - - - - 50032 344.00 0.68 0.455 -0.579668201051643 Down 0.141857086250165 CG42500 CG42500, isoform B - - - - 41896 4163.00 38.97 21.66 -0.84733068856071 Down 0.675703341698587 CG6045 CG6045 K00106|1|6e-143|509|ame:724718|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] - - - 19834768 192.00 2.335 1.795 -0.37943870588661 Down 0.21397437590807 14462396 1405.00 0.115 0.095 -0.275634442613427 Down 0.0530973451327434 318567 700.00 0.175 0.445 1.34645041402143 Up 0.185312376172236 CG31041 CG31041 - - - - 44835 3405.00 0.32 0.17 -0.912537158749661 Down 0.126238277638357 m miniature - GO:0044448//cell cortex part;GO:0005884//actin filament;GO:0031012//extracellular matrix GO:0042302//structural constituent of cuticle GO:0003002//regionalization;GO:0007472//wing disc morphogenesis;GO:0008360//regulation of cell shape;GO:0008544//epidermis development;GO:0032989;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion 48583 2386.00 114.65 74.645 -0.619118823294769 Down 0.666094307224937 Hsp70Bc Heat-shock-protein-70Bc K03283|1|0.0|1147|dme:Dmel_CG31359|heat shock 70kDa protein 1/8 GO:0015630//microtubule cytoskeleton GO:0032559 GO:0034605//cellular response to heat 2768974 1126.00 0.04 0.085 1.08746284125034 Up 0.0725795799762251 ind intermediate neuroblasts defective K09310|1|0.0|640|dme:Dmel_CG11551|homeobox protein GSH GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding GO:0007417//central nervous system development;GO:0003002//regionalization;GO:0009888//tissue development;GO:0001709//cell fate determination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter 40276 1344.00 0.355 0.26 -0.44930740136359 Down 0.0956610751551975 CG5078 CG5078 - GO:0031224//intrinsic to membrane GO:0008493//tetracycline transporter activity GO:0015850//organic hydroxy compound transport;GO:0042221//response to chemical stimulus 37475 853.00 86.91 82.555 -0.0741665897335737 Down 0.193534539690926 CG10306 CG10306 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006413//translational initiation 37898 1007.00 0.425 0.305 -0.478653598574815 Down 0.103982300884956 CG15873 CG15873 K01362|1|2e-28|125|dme:Dmel_CG3795| [EC:3.4.21.-];K01334|2|3e-19|95.5|xla:494791|component factor D [EC:3.4.21.46];K01317|3|2e-18|93.2|tgu:100230182|acrosin [EC:3.4.21.10];K01312|4|1e-17|90.5|oaa:100092420|trypsin [EC:3.4.21.4];K08649|5|1e-17|90.5|mmu:16904|granzyme M [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35354 905.00 32.795 17.56 -0.901183030181433 Down 0.676066569805838 CG14400 CG14400 - - - - 39051 980.00 13.17 10.985 -0.261720475833238 Down 0.35507198520671 Use1 USE1 ortholog K08507|1|6e-28|124|xla:735239|unconventional SNARE in the endoplasmic reticulum protein 1 GO:0043231//intracellular membrane-bounded organelle - - 41771 2524.36 41.825 41.265 -0.0194468998883484 Down 0.0839717342491084 CG14853 CG14853, isoform C - - - - 32077 4279.14 12.505 12.03 -0.0558684150048933 Down 0.121186104873861 CG1737 CG1737, isoform C - - - - 40828 1267.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 zen zerknullt K09311|1|2e-180|632|dme:Dmel_CG1046|Antp family, other;K09310|3|2e-21|103|spu:579267|homeobox protein GSH;K09304|5|7e-19|95.1|cfa:486498|homeobox protein HoxA/B/C/D4 GO:0043231//intracellular membrane-bounded organelle GO:0016564//transcription repressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0001654//eye development;GO:0007447//imaginal disc pattern formation;GO:0010468//regulation of gene expression;GO:0010004//gastrulation involving germ band extension;GO:0009798//axis specification;GO:0006351//transcription, DNA-dependent 33277 9194.56 233.925 317.01 0.43848229709821 Up 0.621219125610884 IA-2 IA-2 ortholog, isoform E K07817|1|0.0|2172|dme:Dmel_CG31795|protein tyrosine phosphatase, receptor type, N [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 7354404 918.90 109.43 113.46 0.0521754650128623 Up 0.155395588429534 Yeti yeti, isoform B - - - - 39841 1833.68 65.02 51.34 -0.340800260114937 Down 0.538006868313301 Mipp1 multiple inositol polyphosphate phosphatase 1, isoform C K03103|1|9e-42|171|dme:Dmel_CG4317|multiple inositol-polyphosphate phosphatase [EC:3.1.3.62] - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity - 14462766 660.00 0.605 0.205 -1.56131123265651 Down 0.23517368907674 47283 1069.09 20.21 13.45 -0.587463148935749 Down 0.580702681283846 SrpRbeta signal recognition particle receptor beta, isoform B K12272|1|8e-134|476|dme:Dmel_CG33162|signal recognition particle receptor subunit beta GO:0030867//rough endoplasmic reticulum membrane GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity GO:0007033//vacuole organization;GO:0006613//cotranslational protein targeting to membrane;GO:0008363//larval chitin-based cuticle development;GO:0006914//autophagy;GO:0006984//ER-nucleus signaling pathway 34030 8590.42 18.285 18.04 -0.0194612880859873 Down 0.0730088495575221 CG42533 zizimin ortholog, isoform K K05727|1|2e-12|77.0|ptr:460402|dedicator of cytokinesis 3/4/5 - GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0030695//GTPase regulator activity - 38129 615.00 1.24 0.7 -0.824913293441909 Down 0.24524501386871 LysP lysozyme P K13915|1|3e-81|300|dme:Dmel_CG9116|lysozyme C [EC:3.2.1.17];K01185|4|8e-62|236|dme:Dmel_CG1179|lysozyme [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 41118 3919.97 32.245 38.54 0.257281102088328 Up 0.442114647998943 Fps85D FER ortholog, isoform F K08889|1|1e-112|407|tgu:100222117|fer (fps/fes related) tyrosine kinase [EC:2.7.10.2];K07527|5|1e-111|404|ssc:100155631|proto-oncogene tyrosine-protein kinase Fes/Fps [EC:2.7.10.2] GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part;GO:0070161;GO:0044424//intracellular part GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0007015//actin filament organization;GO:0042461//photoreceptor cell development;GO:0006935//chemotaxis;GO:0007392;GO:0006464//cellular protein modification process;GO:0007015//actin filament organization;GO:0042461//photoreceptor cell development;GO:0006935//chemotaxis;GO:0007392;GO:0006464//cellular protein modification process;GO:0007015//actin filament organization;GO:0042461//photoreceptor cell development;GO:0006935//chemotaxis;GO:0007392;GO:0006464//cellular protein modification process;GO:0007015//actin filament organization;GO:0042461//photoreceptor cell development;GO:0006935//chemotaxis;GO:0007392;GO:0006464//cellular protein modification process 5740851 1023.00 1.08 0.105 -3.36257007938471 Down 0.413122440892881 CG41284 CG41284 - GO:0044423 - - 41666 3791.67 74.04 77.445 0.0648672036119416 Up 0.173920221899353 sqd squid, isoform E K03102|1|8e-90|331|der:Dere_GG17035|squid - - - 33136 2775.73 4.34 5.335 0.297793228379946 Up 0.273907013604544 Cp110 Cp110, isoform H - - - - 19835789 1625.00 1.06 1.32 0.316473664795254 Up 0.141427816668868 2768872 607.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 Ste:CG33237 Ste:CG33237 K08282|1|2e-95|347|dme:Dmel_CG33237|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 31387 970.00 10.865 11.915 0.133090777008988 Up 0.214700832122573 CG3527 CG3527 - - - - 32903 1852.00 14.68 14.5 -0.017799067940916 Down 0.0677585523708889 CG7453 CG7453 - - - - 35265 1138.39 127.33 86.265 -0.561725126598628 Down 0.653678510104346 fbp fructose-1,6-bisphosphatase, isoform E K03841|1|5e-180|630|dse:Dsec_GM16988|fructose-1,6-bisphosphatase I [EC:3.1.3.11] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0019203//carbohydrate phosphatase activity;GO:0019203//carbohydrate phosphatase activity GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process 14462861 510.31 2.93 2.305 -0.34613391399291 Down 0.225894861973319 CG43679 CG43679, isoform B - - - - 32396 864.00 5.02 4.46 -0.170643654030467 Down 0.178708228767666 nmdyn-D6 nmdyn-D6 K00940|1|7e-82|303|dme:Dmel_CG5310|nucleoside-diphosphate kinase [EC:2.7.4.6] - GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032559 GO:0009209;GO:0009206 50190 392.52 12.98 16.445 0.341358624836264 Up 0.445284638753137 Nplp4 Neuropeptide-like precursor 4, isoform B - - - - 40028 1692.00 0.65 0.755 0.216036926296624 Up 0.0834764231937657 CG32199 CG32199 K00472|1|0.0|969|dse:Dsec_GM14981|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 37782 1710.20 26.37 20.415 -0.36926800363941 Down 0.508486329414873 CG4585 CG4585, isoform D - GO:0044464//cell part GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006644//phospholipid metabolic process 35366 4143.00 0.25 0.975 1.96347412397489 Up 0.330108308017435 CG9270 CG9270 K01509|1|0.0|1689|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3];K05673|2|0.0|1444|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0015405;GO:0005253//anion channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 35051 5166.08 29.69 32.09 0.112146696295152 Up 0.244518557654207 BicD bicaudal D, isoform D K10352|1|7e-14|80.5|aga:AgaP_AGAP010147|myosin heavy chain GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0005515//protein binding GO:0007309//oocyte axis specification;GO:0007097//nuclear migration;GO:0007293//germarium-derived egg chamber formation;GO:0050658//RNA transport;GO:0007017//microtubule-based process 39232 1974.13 105.6 98.235 -0.104300797812712 Down 0.254127592127856 CG7888 CG7888, isoform C - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006865//amino acid transport;GO:0006865//amino acid transport;GO:0006865//amino acid transport 14462856 748.00 0.085 0.12 0.497499659470817 Up 0.0682538634262317 32535 1393.00 0.14 0.34 1.28010791919274 Up 0.155494650640602 CG8509 CG8509 - - GO:0008047//enzyme activator activity - 41428 4126.49 44.92 54.515 0.279295319547737 Up 0.47995641262713 ClC-a chloride channel-a, isoform I K05011|1|1e-178|628|bfo:BRAFLDRAFT_118473|chloride channel 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005254//chloride channel activity;GO:0005254//chloride channel activity;GO:0005254//chloride channel activity;GO:0005254//chloride channel activity;GO:0005254//chloride channel activity;GO:0005254//chloride channel activity GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport 42549 10385.26 6.05 5.97 -0.0192042108971519 Down 0.0559701492537313 InR Insulin-like receptor, isoform D K08252|1|0.0|3902|dme:Dmel_CG18402|receptor protein-tyrosine kinase [EC:2.7.10.1];K04527|2|0.0|871|aag:AaeL_AAEL002317|insulin receptor [EC:2.7.10.1];K05087|4|0.0|822|gga:395889|insulin-like growth factor 1 receptor [EC:2.7.10.1] GO:0030054//cell junction;GO:0005887//integral to plasma membrane;GO:0030054//cell junction;GO:0005887//integral to plasma membrane;GO:0030054//cell junction;GO:0005887//integral to plasma membrane;GO:0030054//cell junction;GO:0005887//integral to plasma membrane GO:0019838//growth factor binding;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0019838//growth factor binding;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0019838//growth factor binding;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0019838//growth factor binding;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0007028//cytoplasm organization;GO:0007444//imaginal disc development;GO:0042078//germ-line stem cell division;GO:0014073;GO:0008283//cell proliferation;GO:0010259//multicellular organismal aging;GO:0060249//anatomical structure homeostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels;GO:0007028//cytoplasm organization;GO:0007444//imaginal disc development;GO:0042078//germ-line stem cell division;GO:0014073;GO:0008283//cell proliferation;GO:0010259//multicellular organismal aging;GO:0060249//anatomical structure homeostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels;GO:0007028//cytoplasm organization;GO:0007444//imaginal disc development;GO:0042078//germ-line stem cell division;GO:0014073;GO:0008283//cell proliferation;GO:0010259//multicellular organismal aging;GO:0060249//anatomical structure homeostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels;GO:0007028//cytoplasm organization;GO:0007444//imaginal disc development;GO:0042078//germ-line stem cell division;GO:0014073;GO:0008283//cell proliferation;GO:0010259//multicellular organismal aging;GO:0060249//anatomical structure homeostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0006468//protein phosphorylation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels 12798502 1772.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 36310 420.00 54.285 42.94 -0.338231417234922 Down 0.530445119535068 CG8860 CG8860 K07342|1|2e-32|136|dya:Dyak_GE13468|protein transport protein SEC61 subunit gamma and related proteins GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0071256 GO:0008320//protein transmembrane transporter activity GO:0007033//vacuole organization;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006914//autophagy 39134 2797.22 0.985 1.605 0.704377667665927 Up 0.254688944657245 CG6761 CG6761, isoform B - - GO:0005488//binding - 41686 807.00 43.22 35.26 -0.293666597539326 Down 0.479229956412627 CG9312 CG9312 - - - - 37182 1576.00 14.175 22.16 0.644609146219597 Up 0.602034077400608 Jheh3 juvenile hormone epoxide hydrolase 3 K10719|1|0.0|970|dme:Dmel_CG15106|juvenile hormone epoxide hydrolase - - - 31802 4804.35 6.07 7.9 0.380156136808783 Up 0.37627129837538 oc ocelliless, isoform G K09326|1|7e-72|273|dme:Dmel_CG12154|homeobox protein OTX GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 40104 1685.14 12.72 4.425 -1.523349310314 Down 0.679071456874917 pip pipe, isoform N K02513|1|5e-29|130|dre:791188|heparan sulfate 2-O-sulfotransferase HS2ST1 [EC:2.8.2.-];K03193|4|1e-26|122|rno:361450|dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST [EC:2.8.2.-] GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification;GO:0009790//embryo development;GO:0035264//multicellular organism growth;GO:0005975//carbohydrate metabolic process;GO:0007292//female gamete generation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0009798//axis specification 246648 1741.00 23.15 8.56 -1.43532949174645 Down 0.711134592524105 Cyp12d1-p Cyp12d1-p, isoform B K00517|1|3e-124|445|dme:Dmel_CG6042| [EC:1.14.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 326139 1221.52 4.4 4.78 0.119507094456089 Up 0.135385021793686 CG31441 CG31441, isoform B K09228|1|6e-33|141|ptr:468734|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 33028 3627.92 2.16 2.405 0.155005581606574 Up 0.117718927486461 CG1504 CG1504, isoform E K06248|1|9e-21|101|mmu:12643|chondroadherin;K13023|5|6e-19|95.1|ecb:100069043|carboxypeptidase N regulatory subunit - GO:0015926//glucosidase activity;GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0006006//glucose metabolic process 3771979 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 19835225 501.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 19835123 408.00 0.11 0.01 -3.4594316186373 Down 0.136970017170783 31764 1084.00 2.015 3.665 0.863033359605844 Up 0.41866992471272 Corp companion of reaper, isoform B - - - - 34863 2505.95 6.24 11.64 0.899473124046036 Up 0.597807423061683 CG15279 CG15279, isoform D K05336|1|0.0|692|dme:Dmel_CG1698|solute carrier family 6 (neurotransmitter transporter), invertebrate GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015171//amino acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 32107 2314.57 13.24 12.95 -0.0319510242333014 Down 0.0854246466781138 nod no distributive disjunction, isoform B K10395|1|3e-48|193|cbr:CBG01568|kinesin family member 4/7/21/27;K10394|5|2e-45|184|dvi:Dvir_GJ12203|kinesin family member 3/17 GO:0005875//microtubule associated complex GO:0008017//microtubule binding;GO:0003676//nucleic acid binding;GO:0003774//motor activity;GO:0032559 GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0007056//spindle assembly involved in female meiosis;GO:0007059//chromosome segregation;GO:0031112;GO:0051294//establishment of spindle orientation 43505 2702.00 4.975 5.16 0.0526745399922431 Up 0.0824858010830802 CG7609 CG7609, isoform C K10865|1|3e-100|366|bmy:Bm1_21560|double-strand break repair protein MRE11;K13341|2|1e-22|108|aag:AaeL_AAEL003117|peroxin-7 - - GO:0006996//organelle organization 41644 2595.99 294.83 314.795 0.094529294944946 Up 0.24362699775459 CG9813 CG9813, isoform G - - - - 37790 1513.00 13.13 11.94 -0.137064079628082 Down 0.231178179896975 Dcp1 decapping protein 1, isoform B K12611|1|0.0|702|dme:Dmel_CG11183|mRNA-decapping enzyme 1B [EC:3.-.-.-] GO:0043232;GO:0030529//ribonucleoprotein complex;GO:0043232;GO:0030529//ribonucleoprotein complex - GO:0019094//pole plasm mRNA localization;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0035194//posttranscriptional gene silencing by RNA;GO:0019094//pole plasm mRNA localization;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0035194//posttranscriptional gene silencing by RNA 35757 861.77 3.14 4.21 0.423055674174769 Up 0.304517236824726 CG14763 CG14763, isoform C K11262|1|7e-14|77.0|aag:AaeL_AAEL006307|acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14] GO:0005875//microtubule associated complex GO:0016887//ATPase activity GO:0007017//microtubule-based process 39457 8603.00 2.985 3.115 0.0615012317591969 Up 0.0735041606128649 CG42588 CG42588, isoform B K11657|1|3e-13|79.7|dre:327618|remodeling and spacing factor 1;K04574|2|2e-12|76.6|bta:528842|neurofilament heavy polypeptide - - - 8674031 1332.00 1.49 2.305 0.629454419967176 Up 0.287247391361775 CG42556 CG42556 - - - - 32447 4791.00 5.26 3.36 -0.646601566513542 Down 0.421905956940959 CG9095 CG9095, isoform D K04011|1|2e-23|112|ptr:449643|complement component (3b/4b) receptor 1 - GO:0030246//carbohydrate binding;GO:0030246//carbohydrate binding GO:0009987//cellular process;GO:0009987//cellular process 39033 986.00 1.725 2.14 0.311014434735615 Up 0.177783648131026 CG5280 CG5280 - - - - 35046 1758.00 0.605 1.455 1.26601210563369 Up 0.332287676660943 CG5043 CG5043 K12478|1|3e-06|53.5|gga:417896|early endosome antigen 1;K10352|2|3e-06|53.5|bta:404108|myosin heavy chain - - - 3772311 519.00 0.32 0.88 1.4594316186373 Up 0.277935543521331 CG33777 CG33777 K09255|1|2e-25|114|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|9e-15|79.3|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 12798488 1018.00 0.245 0.54 1.14017765804826 Up 0.191586316206578 12798436 387.00 0.66 0.5 -0.400537929583729 Down 0.115803724739136 CG43072 CG43072 - - - - 33640 2960.00 10.545 10.955 0.055030389196531 Up 0.115044247787611 CG3338 CG3338 - - - - 41904 1127.00 0.175 0.61 1.80145432061792 Up 0.248943336415269 CG5623 CG5623 - - - - 43564 304.00 0.295 0.17 -0.795180208111502 Down 0.110652489763572 RpS28a ribosomal protein S28a K02979|1|3e-22|102|dme:Dmel_CG15527|small subunit ribosomal protein S28e GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 38342 3020.00 40.405 39.13 -0.0462587230567507 Down 0.142253335094439 CG9977 CG9977 K01251|1|0.0|981|dme:Dmel_CG9977|adenosylhomocysteinase [EC:3.3.1.1] - GO:0016802 GO:0044237//cellular metabolic process 47594 3414.09 62.295 71.25 0.193773641680877 Up 0.391427816668868 aPKC atypical protein kinase C, isoform M K06069|1|0.0|882|dsi:Dsim_GD25642|atypical protein kinase C [EC:2.7.11.13] GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part;GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0044459//plasma membrane part GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046914//transition metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death;GO:0023033;GO:0007611//learning or memory;GO:0007043//cell-cell junction assembly;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0008105//asymmetric protein localization;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007309//oocyte axis specification;GO:0006464//cellular protein modification process;GO:0046666//retinal cell programmed cell death 3772506 1317.00 4.395 9.395 1.09602999627665 Up 0.604972922995641 CG11889 CG11889, isoform B - - - - 39181 1109.00 0.49 0.58 0.243271151012364 Up 0.0815612204464404 CG8072 CG8072 - - - - 318246 3487.49 74.415 80.29 0.109626855459595 Up 0.268095363888522 CG32850 CG32850, isoform B K11980|1|2e-73|277|dme:Dmel_CG32850|E3 ubiquitin-protein ligase RNF11 - - - 35212 1134.66 354.39 339.48 -0.0620113126512887 Down 0.183000924580637 CG17549 CG17549, isoform E - - - - 8674043 344.37 4.52 6.51 0.526334770750448 Up 0.414839519218069 Sfp77F seminal fluid protein 77F, isoform B - - - - 34024 2354.32 67.15 59.305 -0.179233656245484 Down 0.374785365209351 santa-maria scavenger receptor acting in neural tissue and majority of rhodopsin is absent, isoform C K13885|1|5e-55|216|mdo:100029588|scavenger receptor class B, member 1;K12384|3|8e-54|212|bfo:BRAFLDRAFT_126670|lysosome membrane protein 2 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0016108;GO:0007165//signal transduction;GO:0048102//autophagic cell death;GO:0006726//eye pigment biosynthetic process;GO:0006950//response to stress;GO:0016108;GO:0007165//signal transduction;GO:0048102//autophagic cell death;GO:0006726//eye pigment biosynthetic process;GO:0006950//response to stress 32636 441.12 36.73 33.655 -0.126138039396293 Down 0.282129177123233 SmG small ribonucleoprotein particle protein SmG, isoform B K11099|1|7e-38|155|dsi:Dsim_GD15738|small nuclear ribonucleoprotein G GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0030371//translation repressor activity;GO:0003729//mRNA binding;GO:0030371//translation repressor activity;GO:0003729//mRNA binding GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000278//mitotic cell cycle;GO:0006412//translation;GO:0000398//mRNA splicing, via spliceosome;GO:0051234//establishment of localization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 38444 2272.00 3.055 3.26 0.0936995844123479 Up 0.0923590014529124 IntS10 integrator 10 K13147|1|0.0|1195|dme:Dmel_CG1120|integrator complex subunit 10 - - - 31751 3793.35 5.45 6.83 0.325629348625802 Up 0.325386342623167 CG2278 CG2278, isoform C - - - - 37823 1461.98 133.235 146.13 0.133279269864401 Up 0.314852727512878 Phm Peptidylglycine-alpha-hydroxylating monooxygenase, isoform B K00504|1|0.0|721|dme:Dmel_CG3832|peptidylglycine monooxygenase [EC:1.14.17.3] GO:0043231//intracellular membrane-bounded organelle;GO:0042598;GO:0043231//intracellular membrane-bounded organelle;GO:0042598 GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity GO:0031179//peptide modification;GO:0008205//ecdysone metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0007611//learning or memory;GO:0007292//female gamete generation;GO:0009792//embryo development ending in birth or egg hatching;GO:0031179//peptide modification;GO:0008205//ecdysone metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0007611//learning or memory;GO:0007292//female gamete generation;GO:0009792//embryo development ending in birth or egg hatching 19836191 501.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 34924 3664.46 0.88 0.725 -0.279522528622363 Down 0.107416457535332 CycE cyclin E, isoform F K06626|1|0.0|1171|dme:Dmel_CG3938|cyclin E GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity GO:0006277//DNA amplification;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0019827//stem cell maintenance;GO:0006468//protein phosphorylation;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0007399//nervous system development;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0019827//stem cell maintenance;GO:0006468//protein phosphorylation;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0007399//nervous system development;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0019827//stem cell maintenance;GO:0006468//protein phosphorylation;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0007399//nervous system development;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0019827//stem cell maintenance;GO:0006468//protein phosphorylation;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0007399//nervous system development;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0007243//intracellular protein kinase cascade;GO:0065008;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0008356//asymmetric cell division;GO:0048513//organ development;GO:0019827//stem cell maintenance;GO:0006468//protein phosphorylation;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0001709//cell fate determination;GO:0007292//female gamete generation;GO:0007399//nervous system development;GO:0033554//cellular response to stress;GO:0007346//regulation of mitotic cell cycle;GO:0006260//DNA replication 318835 2379.00 0.19 0.63 1.72935241005633 Up 0.251320829480914 CG31601 CG31601, isoform C K13092|1|4e-13|76.6|dse:Dsec_GM17474|nuclear protein NHN1 - GO:0046914//transition metal ion binding - 33507 2878.00 4.615 3.895 -0.244707319584105 Down 0.219158631620658 okr okra K10875|1|0.0|1539|dme:Dmel_CG3736|DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0032559 GO:0009314//response to radiation;GO:0016568//chromatin modification;GO:0006412//translation;GO:0000724//double-strand break repair via homologous recombination;GO:0000087//M phase of mitotic cell cycle;GO:0007292//female gamete generation;GO:0000731//DNA synthesis involved in DNA repair;GO:0006403//RNA localization 40563 3787.04 53.79 57.395 0.0935870722000271 Up 0.225498613129045 eIF3-S10 eIF3-S10, isoform D K03254|1|0.0|1413|dme:Dmel_CG9805|translation initiation factor eIF-3 subunit 10 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008135//translation factor activity, nucleic acid binding GO:0006413//translational initiation;GO:0007052//mitotic spindle organization 42617 1495.00 15.35 14.445 -0.0876684516929261 Down 0.17388720116233 CG7071 CG7071, isoform C - - - - 43740 1114.00 11.005 11.215 0.0272704751947153 Up 0.0771364416853784 nero nero K06072|1|1e-169|595|dme:Dmel_CG2245|deoxyhypusine monooxygenase [EC:1.14.99.29] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004497//monooxygenase activity GO:0018205//peptidyl-lysine modification 14462888 518.73 0.52 0.62 0.253756592245783 Up 0.0850614185708625 59159 543.00 0.92 0.415 -1.14852252471009 Down 0.251783119799234 Lcp65Ag3 larval cuticle protein - - GO:0005214//structural constituent of chitin-based cuticle GO:0002168//instar larval development 50310 723.50 1.47 3.11 1.08109842529424 Up 0.433397173424911 CG8620 CG8620, isoform B - - - - 36568 1225.81 14.59 18.825 0.3676699816414 Up 0.47695152555805 CG18324 CG18324, isoform B K03454|1|8e-97|353|dpo:Dpse_GA20987|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 42596 2905.76 52.87 40.285 -0.392206571191108 Down 0.559635451063268 how held out wings, isoform F K13095|1|9e-171|601|dya:Dyak_GE10266|splicing factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0016477//cell migration;GO:0007272;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0001742//oenocyte differentiation;GO:0007509//mesoderm migration involved in gastrulation;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0016477//cell migration;GO:0007272;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0001742//oenocyte differentiation;GO:0007509//mesoderm migration involved in gastrulation;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0016477//cell migration;GO:0007272;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0001742//oenocyte differentiation;GO:0007509//mesoderm migration involved in gastrulation;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0016477//cell migration;GO:0007272;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0001742//oenocyte differentiation;GO:0007509//mesoderm migration involved in gastrulation;GO:0008587//imaginal disc-derived wing margin morphogenesis;GO:0016477//cell migration;GO:0007272;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0001742//oenocyte differentiation;GO:0007509//mesoderm migration involved in gastrulation;GO:0008587//imaginal disc-derived wing margin morphogenesis 34157 847.43 6.95 7.215 0.0539864168803281 Up 0.0921278562937525 CG13392 CG13392, isoform B - - - - 19836254 477.00 2.65 3.41 0.363779379573611 Up 0.252443534539691 41479 3897.29 14.045 17.735 0.33654270580879 Up 0.452218993527936 CG4848 CG4848, isoform C - - - - 12798245 1355.28 15.96 15.555 -0.0370822566879641 Down 0.102595429929996 19835958 1321.00 15.5 11.635 -0.413797004756251 Down 0.480088495575221 41357 898.00 7.44 3.97 -0.906163613965073 Down 0.542761854444591 scpr-B SCP-containing protein B K00747|1|9e-09|60.8|tca:656110|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] - - - 39404 3112.65 14.9 12.255 -0.281941846482684 Down 0.3878615770704 CG10426 CG10426, isoform B K01099|1|0.0|1421|dme:Dmel_CG10426|phosphatidylinositol-bisphosphatase [EC:3.1.3.36] GO:0012505//endomembrane system;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005930//axoneme GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity GO:0001503//ossification;GO:0048562//embryonic organ morphogenesis;GO:0006650//glycerophospholipid metabolic process;GO:0010975//regulation of neuron projection development 37280 1035.00 1.38 1.88 0.446064394899469 Up 0.212290318319905 CG16894 CG16894 - - - - 41788 5694.86 22.81 25.42 0.156297583692822 Up 0.30514463082816 jvl javelin-like, isoform G - - - - 33635 2730.00 167.265 170.24 0.0254344611971196 Up 0.11352529388456 CG16857 CG16857 K06765|1|5e-23|110|dre:569360|deleted in colorectal carcinoma;K06766|3|1e-21|105|rno:81735|neogenin - - - 33496 7508.21 12.79 11.795 -0.116840845642174 Down 0.202285035001981 lilli lilliputian, isoform H - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007635//chemosensory behavior;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0010468//regulation of gene expression;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032535//regulation of cellular component size;GO:0006869//lipid transport;GO:0033043//regulation of organelle organization;GO:0007365//periodic partitioning;GO:0001751//compound eye photoreceptor cell differentiation 3772130 173.00 0.465 0.21 -1.14684138832927 Down 0.176033549068815 19835963 300.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 41714 3476.00 9.81 10.915 0.153987088771552 Up 0.231673490952318 CG12402 CG12402, isoform B K10275|1|0.0|1213|dme:Dmel_CG12402|F-box and leucine-rich repeat protein 9 - - - 40035 800.00 9.365 9.055 -0.0485643532928776 Down 0.098864086646414 Sgf11 Sgf11 - GO:0070461//SAGA-type complex GO:0043169//cation binding GO:0016477//cell migration;GO:0006355//regulation of transcription, DNA-dependent;GO:0016570//histone modification;GO:0007154//cell communication 42930 4368.05 34.835 20.865 -0.739452642690566 Down 0.654437987055871 CG13624 CG13624, isoform G - - GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding - 14462658 780.00 21.315 8.805 -1.27547414613273 Down 0.694062871483291 117459 573.00 0.145 0.01 -3.85798099512757 Down 0.168967111345925 TotZ turandot Z - GO:0044421//extracellular region part - GO:0009416//response to light stimulus;GO:0006952//defense response 31712 2528.03 59.74 49.5 -0.271268712456456 Down 0.473253203011491 l(1)G0193 lethal (1) G0193, isoform B - - - - 32596 1800.08 89.36 91.75 0.0380789721346226 Up 0.13287544577995 CG9917 CG9917, isoform B - - - - 3772163 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33809 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 3771892 965.00 0.64 0.47 -0.445411148322363 Down 0.120987980451724 gdl-ORF39 gdl-ORF39 - - - GO:0007292//female gamete generation 38924 1624.00 0.05 0.285 2.51096191927738 Up 0.188845595033681 CG7213 CG7213 - - - - 40203 1237.00 0.685 0.795 0.214850872323829 Up 0.0858208955223881 CG7335 CG7335 K00846|1|0.0|701|dme:Dmel_CG7335|ketohexokinase [EC:2.7.1.3] - - - 3771886 164.00 0.36 0.01 -5.16992500144231 Down 0.301512349755647 41948 1047.00 0.08 0.085 0.0874628412503394 Up 0.0429929996037512 CG10264 CG10264 - - - - 3346237 2385.00 0.06 0.02 -1.58496250072116 Down 0.0744287412495047 nab nab, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0008134//transcription factor binding GO:0007447//imaginal disc pattern formation;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048468//cell development;GO:0007610//behavior;GO:0007447//imaginal disc pattern formation;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048468//cell development;GO:0007610//behavior 38719 2247.00 2.3 1.94 -0.245577208757248 Down 0.155131422533351 CG7386 CG7386 K09228|1|3e-49|196|mmu:212281|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 5740147 4662.00 29.815 40.94 0.45747276559924 Up 0.582320697397966 CG17159 CG17159, isoform F - - - - 33894 1397.00 73.275 38.95 -0.911697734627872 Down 0.705917316074495 CG42369 CG42369 - - - - 318684 2719.00 0.47 0.705 0.584962500721156 Up 0.144762911108176 CG31327 CG31327 - - - - 33399 2956.00 7.53 7.245 -0.0556641751149988 Down 0.100184916127328 mio missing oocyte K10752|1|2e-09|65.5|nve:NEMVE_v1g165676|histone-binding protein RBBP4 - GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction 35380 3163.00 1.02 1.55 0.603699063302742 Up 0.228371417250033 del deadlock, isoform C - - - - 44038 896.00 77.065 63.395 -0.281706732848616 Down 0.491711795007265 Hf helical factor - - - - 318016 1231.00 7.44 7.24 -0.0393129240248258 Down 0.080768722757892 CG32409 CG32409 K10455|1|2e-17|90.5|tca:661567|kelch-like protein 18 GO:0043231//intracellular membrane-bounded organelle - GO:0022613//ribonucleoprotein complex biogenesis 35543 1662.58 209.2 71.89 -1.5410198427585 Down 0.768953903051116 Cyp6w1 Cyp6w1, isoform B K00517|1|0.0|1022|dme:Dmel_CG8345| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 39625 2320.55 19.285 28.445 0.560695935065999 Up 0.598963148857482 mnd minidiscs, isoform D K03450|1|0.0|833|dpo:Dpse_GA23621|solute carrier family 7 (L-type amino acid transporter), other;K13780|2|2e-120|433|bta:282369|solute carrier family 7 (L-type amino acid transporter), member 5 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity GO:0015820//leucine transport;GO:0015820//leucine transport;GO:0015820//leucine transport 12798268 910.06 8.95 11.815 0.400660041822228 Up 0.442048606524898 19834748 331.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 33911 1441.00 22.21 17.915 -0.310041349336245 Down 0.45145951657641 CG9547 CG9547 K00252|1|0.0|829|der:Dere_GG23615|glutaryl-CoA dehydrogenase [EC:1.3.99.7] GO:0031980;GO:0015630//microtubule cytoskeleton GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0030554//adenyl nucleotide binding GO:0009068;GO:0006586;GO:0006553//lysine metabolic process 38742 3810.00 15.085 16.67 0.144139407839715 Up 0.252905824858011 Glu-RI glutamate receptor IA K05313|1|0.0|1888|dme:Dmel_CG8442|glutamate receptor, ionotropic, invertebrate GO:0044459//plasma membrane part;GO:0030313;GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 12798475 890.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 19835048 487.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 326117 1401.00 0.87 1.06 0.284976958714471 Up 0.116398098005547 CG31099 CG31099 - - - - 41339 1819.12 43.06 37.14 -0.213374504231813 Down 0.396678113855501 cu curled, isoform H K12603|1|3e-16|87.0|spu:580732|CCR4-NOT transcription complex subunit 6 [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 42140 1787.00 21.51 20.28 -0.0849498724197202 Down 0.179698850878352 CG7379 CG7379 K11345|1|2e-17|90.9|xtr:394462|inhibitor of growth protein 5;K11346|5|3e-17|90.1|bfo:BRAFLDRAFT_114530|inhibitor of growth protein 4 - - - 19836032 2671.00 0.055 0.195 1.82597060022495 Up 0.13380002641659 - pre-mod(mdg4)-J - - - - 41470 3300.97 15.53 17.005 0.130901176320541 Up 0.239763571522916 dpr17 dpr17, isoform E K01530|1|2e-17|91.7|der:Dere_GG17161|phospholipid-translocating ATPase [EC:3.6.3.1] - - - 41852 1357.69 709.015 521.21 -0.443951385705608 Down 0.625148593316603 Tm1 tropomyosin 1, isoform S K10373|1|3e-134|478|dme:Dmel_CG4898|tropomyosin 1;K09290|3|1e-79|296|cel:Y105E8B.1|tropomyosin 3;K10374|4|2e-78|293|ame:408414|tropomyosin 2 GO:0005865//striated muscle thin filament GO:0008092//cytoskeletal protein binding GO:0030032//lamellipodium assembly;GO:0019094//pole plasm mRNA localization;GO:0003012//muscle system process;GO:0048812//neuron projection morphogenesis 48339 780.00 0.58 0.115 -2.33441903907056 Down 0.274237220974772 GstD6 glutathione S transferase D6 K00799|1|2e-112|404|dme:Dmel_CG4423|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups - 10178909 720.00 0.66 0.615 -0.101879614019214 Down 0.0586118082155594 CG42830 CG42830 - GO:0031224//intrinsic to membrane GO:0046872//metal ion binding GO:0042742//defense response to bacterium;GO:0016337//cell-cell adhesion;GO:0031349//positive regulation of defense response;GO:0048513//organ development 318910 4895.00 0.055 0.095 0.788495894806288 Up 0.0694426099590543 CG43672 CG43672 K05643|1|6e-42|174|mdo:100013281|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0015405;GO:0030247//polysaccharide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0006022 43255 3655.03 0.235 0.305 0.376148485885249 Up 0.0819904900277374 Nep5 neprilysin 5, isoform F K01415|1|4e-95|350|cel:F18A12.8|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|2e-94|347|cqu:CpipJ_CPIJ002051|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 32930 5658.22 7.225 8.27 0.194889741783234 Up 0.24362699775459 kek5 kekkon5, isoform D K07523|1|2e-44|181|dme:Dmel_CG4192|netrin-G1 ligand;K06838|2|3e-18|95.1|xla:380270|slit 1 GO:0016020//membrane;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding GO:0030509//BMP signaling pathway;GO:0030509//BMP signaling pathway 40136 963.00 31.11 3.215 -3.27448775220643 Down 0.803658697662132 lush lush, isoform B - - GO:0043178//alcohol binding;GO:0035273;GO:0043178//alcohol binding;GO:0035273 GO:0007606//sensory perception of chemical stimulus;GO:0051234//establishment of localization;GO:0010033//response to organic substance;GO:0007635//chemosensory behavior;GO:0007606//sensory perception of chemical stimulus;GO:0051234//establishment of localization;GO:0010033//response to organic substance;GO:0007635//chemosensory behavior 32537 5692.48 99.385 102.085 0.0386708674540771 Up 0.133667943468498 Chc clathrin heavy chain, isoform G K04646|1|0.0|3200|der:Dere_GG19369|clathrin, heavy polypeptide GO:0005626//insoluble fraction;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//coated pit;GO:0042383//sarcolemma;GO:0030125//clathrin vesicle coat;GO:0005626//insoluble fraction;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//coated pit;GO:0042383//sarcolemma;GO:0030125//clathrin vesicle coat;GO:0005626//insoluble fraction;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//coated pit;GO:0042383//sarcolemma;GO:0030125//clathrin vesicle coat;GO:0005626//insoluble fraction;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//coated pit;GO:0042383//sarcolemma;GO:0030125//clathrin vesicle coat;GO:0005626//insoluble fraction;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//coated pit;GO:0042383//sarcolemma;GO:0030125//clathrin vesicle coat;GO:0005626//insoluble fraction;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//coated pit;GO:0042383//sarcolemma;GO:0030125//clathrin vesicle coat GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0050658//RNA transport;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0000087//M phase of mitotic cell cycle;GO:0043062//extracellular structure organization;GO:0050658//RNA transport;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0000087//M phase of mitotic cell cycle;GO:0043062//extracellular structure organization;GO:0050658//RNA transport;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0000087//M phase of mitotic cell cycle;GO:0043062//extracellular structure organization;GO:0050658//RNA transport;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0000087//M phase of mitotic cell cycle;GO:0043062//extracellular structure organization;GO:0050658//RNA transport;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0000087//M phase of mitotic cell cycle;GO:0043062//extracellular structure organization;GO:0050658//RNA transport;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0035151//regulation of tube size, open tracheal system;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0000087//M phase of mitotic cell cycle;GO:0043062//extracellular structure organization 34401 1405.00 0.085 0.095 0.160464672193246 Up 0.045238409721305 CG5367 CG5367 K01375|1|1e-63|243|mcc:710850|cathepsin V [EC:3.4.22.43];K01365|2|3e-63|242|bta:281108|cathepsin L [EC:3.4.22.15] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19834819 292.00 2.4 1.07 -1.16542360920737 Down 0.403513406419231 2768996 1536.46 47.515 40.43 -0.232956825821835 Down 0.423325848632941 CG33229 CG33229, isoform B - - - - 42698 1312.00 0.525 0.52 -0.0138057995250304 Down 0.041044776119403 CG31139 CG31139, isoform C K13667|1|3e-106|385|dpo:Dpse_GA16050|protein glucosyltransferase [EC:2.4.1.-] GO:0044432//endoplasmic reticulum part GO:0035251//UDP-glucosyltransferase activity GO:0008593//regulation of Notch signaling pathway;GO:0006486//protein glycosylation 43515 1032.98 173.545 141.515 -0.294354819498371 Down 0.518062343151499 CG7834 CG7834, isoform B K03521|1|2e-106|385|dsi:Dsim_GD17660|electron transfer flavoprotein beta subunit GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part - GO:0006091//generation of precursor metabolites and energy;GO:0006091//generation of precursor metabolites and energy 33012 3053.15 0.515 0.515 0 - 0.0382380134724607 CG15322 CG15322, isoform C - - - - 39689 2515.00 3.14 2.72 -0.207157907641288 Down 0.161867652886012 CG12301 CG12301 K03243|1|7e-08|59.7|mcc:714129|translation initiation factor IF-2 unclassified subunit GO:0030684//preribosome - GO:0042254//ribosome biogenesis;GO:0007420//brain development 35189 2052.00 35.545 33.28 -0.0949912014000385 Down 0.213842292959979 CG10561 CG10561 K00308|1|1e-39|165|xla:495472|N1-acetylpolyamine oxidase [EC:1.5.3.13];K12259|2|9e-35|148|tgu:100232049|spermine oxidase [EC:1.5.3.16] GO:0044424//intracellular part - - 12798296 644.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 35564 3217.93 5.705 7.6 0.413772532042266 Up 0.385814291374983 sced scrambled, isoform B - GO:0005815//microtubule organizing center - GO:0001700//embryonic development via the syncytial blastoderm 246625 1190.04 0.71 1.615 1.18564323518924 Up 0.337868181217805 CG43328 CG43328, isoform B - - - - 31537 8295.33 11.545 14.02 0.280218176236508 Up 0.380299828292167 CG5937 CG5937, isoform D - - - - 37325 682.00 4.125 4.175 0.0173820782282362 Up 0.0513472460705323 Nnf1a Nnf1a - - - - 5740407 478.00 14.675 10.355 -0.503032949776903 Down 0.515849953770968 CG34163 CG34163, isoform B - - - - 19835720 752.00 0.01 0.2 4.32192809488736 Up 0.209648659358077 31344 9169.44 11.21 18.035 0.686013144982143 Up 0.595793158103289 CG42541 CG42541, isoform F K07847|1|1e-46|189|ame:411209|Rad and Gem related GTP binding protein 1 GO:0044464//cell part;GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction 42208 1496.49 1.85 0.5 -1.88752527074159 Down 0.433562277110025 WRNexo WRN exonuclease, isoform C K10900|1|2e-25|117|rno:290805|werner syndrome ATP-dependent helicase [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0004527//exonuclease activity;GO:0043169//cation binding GO:0000019//regulation of mitotic recombination 19834942 408.00 0.21 0.01 -4.39231742277876 Down 0.216153744551578 5740788 2858.00 0.575 0.155 -1.8912937405575 Down 0.247787610619469 CG34382 CG34382, isoform F - - - - 34120 536.00 38.43 37.96 -0.0177529840416933 Down 0.0822216351868974 Ssb-c31a single stranded-binding protein c31A - GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0043566//structure-specific DNA binding GO:0006355//regulation of transcription, DNA-dependent 38435 1111.00 0.01 0.235 4.55458885167764 Up 0.229362039360719 CG10357 CG10357 K01059|1|8e-31|134|dpo:Dpse_GA18274|lipoprotein lipase [EC:3.1.1.34];K01046|2|6e-29|128|mdo:100027041|triacylglycerol lipase [EC:3.1.1.3] GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0044238//primary metabolic process 35216 702.00 2.71 0.605 -2.16328580407928 Down 0.520175670320962 Lectin-galC1 Galactose-specific C-type lectin, isoform B K06560|1|2e-10|65.5|bfo:BRAFLDRAFT_80311|mannose receptor, C type;K10061|3|8e-09|60.5|oaa:100081235|C-type lectin superfamily 4, member G;K06561|4|1e-08|60.1|ptr:737419|CD207 antigen - GO:0048029//monosaccharide binding;GO:0004871//signal transducer activity;GO:0051635//bacterial cell surface binding;GO:0048029//monosaccharide binding;GO:0004871//signal transducer activity;GO:0051635//bacterial cell surface binding GO:0019731//antibacterial humoral response;GO:0019731//antibacterial humoral response 33478 1961.00 0.045 0.07 0.637429920615292 Up 0.0622440892880729 CG3123 CG3123 - - - - 19834728 1801.00 0.04 0.01 -2 Down 0.0694426099590543 2768869 620.68 63.16 53.615 -0.236374487714104 Down 0.443897767798177 CG34330 CG34330, isoform B - - - - 38616 2580.00 0.02 0.02 0 - 0.0382380134724607 Ir64a ionotropic receptor 64a - GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 31254 1750.61 2.365 2.07 -0.19220941584007 Down 0.131356491876899 CG2662 CG2662, isoform B K11465|1|3e-08|60.5|aga:AgaP_AGAP003268|sex comb on midleg-like protein 2;K11456|3|8e-08|58.9|mdo:100012285|polyhomeotic-like protein 1;K11461|4|1e-07|58.5|dme:Dmel_CG9495|polycomb protein SCMH1;K11306|5|2e-07|57.8|aag:AaeL_AAEL011106|histone acetyltransferase MYST4 [EC:2.3.1.48] - - - 32748 5451.85 17.53 16.79 -0.0622237658225082 Down 0.139347510236428 chas chascon, isoform E K06051|1|5e-11|71.2|ame:410351|delta - - - 3885610 469.00 0.715 0.34 -1.07240849552805 Down 0.216252806762647 CG34007 CG34007, isoform B - - - - 42243 2328.00 12.33 10.27 -0.263736618084644 Down 0.348071588957866 CG7705 CG7705, isoform B - - - - 42017 2423.00 52.785 29.335 -0.847505022799456 Down 0.688053097345133 CG10345 CG10345 K13885|1|1e-38|162|ssc:397018|scavenger receptor class B, member 1 - - - 37937 1936.00 7.29 7.895 0.1150204515333 Up 0.166292431647074 CG42360 CG42360 - - - - 38648 4071.54 26.66 22.78 -0.226909033380861 Down 0.389314489499406 scny scrawny, isoform J K11855|1|0.0|1452|dme:Dmel_CG5505|ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.1.2.15] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process;GO:0019827//stem cell maintenance;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0019827//stem cell maintenance;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0019827//stem cell maintenance;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0019827//stem cell maintenance;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0019827//stem cell maintenance;GO:0070646//protein modification by small protein removal 43806 2914.41 22.59 36.65 0.69812892762809 Up 0.646446968696341 CG9935 CG9935, isoform D K05202|1|9e-174|496|ecb:100066235|glutamate receptor, ionotropic, kainate 2 - - - 39517 2522.05 28.535 29.74 0.0596720843759685 Up 0.155758816536785 CG10089 CG10089, isoform F K01090|1|3e-38|159|mmu:252864|protein phosphatase [EC:3.1.3.16];K01104|1|3e-38|159|mmu:252864|protein-tyrosine phosphatase [EC:3.1.3.48];K04459|2|1e-20|100|phu:Phum_PHUM490910|dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 39593 1109.29 146.32 113.235 -0.369807028019418 Down 0.577004358737287 CG9628 CG9628, isoform C - - - - 35713 1001.00 5.57 4.44 -0.327117650989926 Down 0.297714964998019 U2A U2A K11092|1|7e-119|426|dme:Dmel_CG1406|U2 small nuclear ribonucleoprotein A' GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0003723//RNA binding GO:0000278//mitotic cell cycle;GO:0000377 33259 1246.00 3.2 2.915 -0.134576021686866 Down 0.120723814555541 Clp clipper K06093|1|6e-10|65.5|hmg:100206476|partitioning defective protein 6 GO:0005849//mRNA cleavage factor complex GO:0046914//transition metal ion binding GO:0031124//mRNA 3'-end processing 36962 1700.00 0.225 0.31 0.4623432140572 Up 0.0881323471139876 CG10764 CG10764 K08664|1|8e-29|128|mdo:100019340|protease, serine, 8 (prostasin) [EC:3.4.21.-];K01314|2|1e-26|121|tgu:100221743|coagulation factor X [EC:3.4.21.6];K01321|3|2e-26|120|hsa:2158|coagulation factor IX (Christmas factor) [EC:3.4.21.22] - - - 39617 3866.11 3.04 2.955 -0.0409131932660531 Down 0.0603288865407476 DCX-EMAP Doublecortin-domain-containing echinoderm-microtubule-associated protein ortholog, isoform G K03130|1|6e-08|60.5|phu:Phum_PHUM362800|transcription initiation factor TFIID subunit D4;K12602|3|3e-06|55.1|cin:100182087|WD repeat-containing protein 61 - GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0009987//cellular process;GO:0023033;GO:0009987//cellular process;GO:0023033 40171 5450.94 28.63 26.065 -0.135413810403341 Down 0.284902919033153 Su(Tpl) Su(Tpl), isoform C K06088|1|2e-07|58.9|dre:405757|occludin GO:0005694//chromosome;GO:0005694//chromosome GO:0030528//transcription regulator activity;GO:0030528//transcription regulator activity GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0033554//cellular response to stress;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0033554//cellular response to stress 3771984 3404.00 1.265 1.525 0.269671857755938 Up 0.133139611676133 CG18749 CG18749, isoform C K00472|1|0.0|960|dme:Dmel_CG18749|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding;GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019798 GO:0023060;GO:0019471 31209 1247.00 12.89 15.77 0.290930396428859 Up 0.402291639149386 CG3191 CG3191, isoform C K10693|1|1e-67|256|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] - - - 33227 1736.00 32.565 28.29 -0.203030049940048 Down 0.371318187821952 Spp signal peptide peptidase K09595|1|0.0|710|dme:Dmel_CG11840|minor histocompatibility antigen H13 [EC:3.4.99.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0004190//aspartic-type endopeptidase activity GO:0060541//respiratory system development;GO:0051603//proteolysis involved in cellular protein catabolic process 19835900 600.00 0.145 0.4 1.46394709975979 Up 0.182505613525294 - CG45490 - - - - 42942 405.00 35.35 39.315 0.153369639352812 Up 0.315447100779289 Rpb10 Rpb10 K03007|1|2e-34|143|dvi:Dvir_GJ23650|DNA-directed RNA Polymerase II subunit L GO:0016591//DNA-directed RNA polymerase II, holoenzyme GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0016301//kinase activity GO:0006396//RNA processing;GO:0006354//DNA-dependent transcription, elongation;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 37734 2825.38 7.37 7.645 0.052851882265735 Up 0.0950667018887862 apt apontic, isoform F - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0017148//negative regulation of translation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0048513//organ development;GO:0060446//branching involved in open tracheal system development;GO:0017148//negative regulation of translation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0048513//organ development;GO:0060446//branching involved in open tracheal system development;GO:0017148//negative regulation of translation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0048513//organ development;GO:0060446//branching involved in open tracheal system development;GO:0017148//negative regulation of translation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0048513//organ development;GO:0060446//branching involved in open tracheal system development;GO:0017148//negative regulation of translation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0048513//organ development;GO:0060446//branching involved in open tracheal system development 37484 1201.00 0.26 1.18 2.18220333122075 Up 0.372176726984546 CG4021 CG4021 K13198|1|1e-33|143|bta:538775|KH domain-containing, RNA-binding, signal transduction-associated protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0012501//programmed cell death 43441 2196.00 1.62 2.665 0.718141719874551 Up 0.331065909391098 dgt6 dim gamma-tubulin 6 - GO:0015630//microtubule cytoskeleton - GO:0007067//mitosis 2768681 1018.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG33339 CG33339 - - - - 38098 1795.08 0.765 0.6 -0.350497247084133 Down 0.113657376832651 Gr61a gustatory receptor 61a, isoform C K08471|1|0.0|853|dme:Dmel_CG13888|gustatory receptor - - - 246417 670.00 3.16 15.965 2.33691608939299 Up 0.739961695945053 CG30050 CG30050 - - - - 32780 6259.18 50.085 75.785 0.597533732280793 Up 0.652753929467706 Sh shaker, isoform O K05318|1|0.0|949|dan:Dana_GF19526|potassium voltage-gated channel Shaker-related subfamily A, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005244//voltage-gated ion channel activity GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior;GO:0009583//detection of light stimulus;GO:0007626//locomotory behavior;GO:0030001//metal ion transport;GO:0030534//adult behavior;GO:0007635//chemosensory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0050804//regulation of synaptic transmission;GO:0048588//developmental cell growth;GO:0042391//regulation of membrane potential;GO:0007606//sensory perception of chemical stimulus;GO:0007617//mating behavior 39244 1705.95 15.05 21.005 0.480969298839453 Up 0.544776119402985 APP-BP1 beta-Amyloid precursor protein binding protein 1, isoform B K04532|1|0.0|1009|dme:Dmel_CG7828|amyloid beta precursor protein binding protein 1 - - - 42972 4612.45 17.18 17.53 0.0290959596210748 Up 0.0899154669132215 CG3744 CG3744, isoform G K08655|1|3e-169|596|cin:100180483|dipeptidyl-peptidase 8 [EC:3.4.14.5];K08656|2|2e-167|590|xtr:779598|dipeptidyl-peptidase 9 [EC:3.4.14.5] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 10178930 359.00 0.01 0.14 3.8073549220576 Up 0.163848897107383 CG42759 CG42759 - - - - 32861 680.00 1.055 0.33 -1.67670506934873 Down 0.321555937128517 CG6873 CG6873 K05765|1|1e-76|285|dse:Dsec_GM22788|cofilin GO:0044464//cell part GO:0008092//cytoskeletal protein binding - 42297 2292.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 nos nanos, isoform B K10836|1|1e-11|72.4|dme:Dmel_CG11779|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005737//cytoplasm GO:0005515//protein binding;GO:0030554//adenyl nucleotide binding;GO:0005506//iron ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0003723//RNA binding GO:0008354//germ cell migration;GO:0048812//neuron projection morphogenesis;GO:0006412//translation;GO:0007143//female meiosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0031124//mRNA 3'-end processing;GO:0048513//organ development;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0019827//stem cell maintenance;GO:0040008//regulation of growth;GO:0007309//oocyte axis specification;GO:0006915//apoptotic process;GO:0000578//embryonic axis specification;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0006260//DNA replication 50323 609.00 29.905 30.06 0.0074582916490145 Up 0.0592722229560164 CG15210 CG15210 - - - - 33594 577.00 59.98 65.075 0.117621884422734 Up 0.281237617223616 CG10031 CG10031 K06238|1|4e-10|64.3|ptr:460045|collagen, type VI, alpha;K03909|4|2e-09|62.0|rno:29436|tissue factor pathway inhibitor - GO:0004866//endopeptidase inhibitor activity - 318924 1082.00 0.325 0.24 -0.437405312307298 Down 0.0918306696605468 CG31742 proteasome beta5 subunit-related 2, isoform B K02737|1|6e-153|540|dme:Dmel_CG31742|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0006508//proteolysis 19835549 291.00 0.01 0.215 4.4262647547021 Up 0.216153744551578 317858 1376.00 0.45 0.52 0.208586621811418 Up 0.0727446836613393 CG32110 CG32110 K03345|1|3e-49|196|gga:424864|sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.-];K08592|2|7e-49|194|xla:398517|sentrin-specific protease 1 [EC:3.4.22.-] GO:0019866//organelle inner membrane;GO:0005635//nuclear envelope GO:0019783//small conjugating protein-specific protease activity GO:0051604//protein maturation 37912 3959.67 39.38 38.945 -0.01602499317691 Down 0.0812310130762119 Letm1 LETM1 ortholog, isoform C K10352|1|1e-07|59.7|phu:Phum_PHUM098460|myosin heavy chain;K04648|2|3e-07|58.5|bfo:BRAFLDRAFT_126882|dynactin 1;K12478|4|3e-07|58.2|ptr:467212|early endosome antigen 1;K06636|5|4e-07|57.8|dwi:Dwil_GK11152|structural maintenance of chromosome 1 - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - 35924 691.00 26.25 25.67 -0.032234126865429 Down 0.0990291903315282 tsu tsunagi K12876|1|3e-86|317|dya:Dyak_GE19253|RNA-binding protein 8A GO:0005681//spliceosomal complex GO:0003723//RNA binding GO:0007010//cytoskeleton organization;GO:0007097//nuclear migration;GO:0044087;GO:0019094//pole plasm mRNA localization;GO:0000377;GO:0006405//RNA export from nucleus 14462730 1241.00 4.49 4.945 0.139255076017964 Up 0.155032360322282 43795 11011.05 12.4 13.665 0.140145339248969 Up 0.236461497820631 zfh2 Zn finger homeodomain 2, isoform C K09380|1|0.0|4976|dme:Dmel_CG1449|zinc finger homeobox protein 4;K09378|3|1e-106|389|ame:410304|AT-binding transcription factor 1 - - - 32065 650.00 1.535 2.33 0.602091299284101 Up 0.282129177123233 CG15198 CG15198 - - - - 37165 3786.37 20.77 22.635 0.124054090403192 Up 0.244155329546955 Mctp multiple C2 domain and transmembrane region protein, isoform F K02677|1|4e-12|74.7|phu:Phum_PHUM528520|classical protein kinase C [EC:2.7.11.13] - - - 34300 1454.98 224.05 201.415 -0.153649597168668 Down 0.351604807819311 IP3K1 inositol 1,4,5-triphosphate kinase 1, isoform B K00911|1|0.0|756|dme:Dmel_CG4026|1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] - GO:0051766//inositol trisphosphate kinase activity;GO:0005515//protein binding GO:0006950//response to stress 33923 7691.03 35.2 33.895 -0.0545029580739316 Down 0.142616563201691 CG11319 CG11319, isoform C K01278|1|5e-85|317|cin:100178732|dipeptidyl-peptidase 4 [EC:3.4.14.5] GO:0044464//cell part GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 42120 524.00 0.325 0.19 -0.774440299584869 Down 0.118544445912033 CG14326 CG14326 - - - - 40809 830.00 2.075 1.58 -0.393186778057184 Down 0.204695548804649 sowi solwind - - GO:0046872//metal ion binding - 35867 1141.00 1.11 1.65 0.57190634789571 Up 0.22856954167217 CG8746 CG8746 - - - - 38347 10978.61 14.13 16.99 0.265924386850281 Up 0.390106987187954 CG43444 CG43444, isoform F K13097|1|5e-106|387|tgu:100218736|methylcytosine dioxygenase [EC:1.14.11.-] - - - 3772390 1116.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 CG33700 CG33700 K12602|1|1e-14|80.5|dpo:Dpse_GA17766|WD repeat-containing protein 61;K09255|2|2e-11|70.5|dpe:Dper_GL18753|Rel/ankyrin family, other - - - 39469 1146.00 0.14 0.34 1.28010791919274 Up 0.155494650640602 CG10748 CG10748 K00026|1|1e-172|605|dme:Dmel_CG10748|malate dehydrogenase [EC:1.1.1.37] GO:0031980 GO:0016615//malate dehydrogenase activity GO:0009060//aerobic respiration;GO:0043648//dicarboxylic acid metabolic process;GO:0006007//glucose catabolic process 34667 911.00 0.115 0.05 -1.20163386116965 Down 0.0859859992075023 Ref2 RNA and export factor binding protein 2, isoform C K12881|1|5e-19|94.7|dme:Dmel_CG1101|THO complex subunit 4 GO:0044428//nuclear part GO:0005488//binding GO:0006405//RNA export from nucleus 12798152 375.00 0.12 0.26 1.11547721741994 Up 0.126766609430722 CG43229 CG43229, isoform B - - - - 326156 1610.24 82.835 57.46 -0.527682480860535 Down 0.634955752212389 CG31743 CG31743, isoform B K01025|1|0.0|635|dme:Dmel_CG31743| [EC:2.8.2.-];K01017|3|1e-53|211|api:100160220|chondroitin 4-sulfotransferase 11 [EC:2.8.2.5];K07779|4|5e-48|192|rno:500257|chondroitin 4-sulfotransferase 13 [EC:2.8.2.5] GO:0031224//intrinsic to membrane GO:0016782//transferase activity, transferring sulfur-containing groups GO:0005975//carbohydrate metabolic process 33914 2629.60 48.15 43.07 -0.160852474488963 Down 0.336514330999868 CG31637 CG31637, isoform B K01025|1|0.0|921|dme:Dmel_CG31637| [EC:2.8.2.-];K04746|3|2e-19|98.2|mmu:26887|carbohydrate 6-sulfotransferase 4 [EC:2.8.2.-];K09671|5|6e-19|96.7|rno:307859|carbohydrate 6-sulfotransferase 6 [EC:2.8.2.-] - GO:0016782//transferase activity, transferring sulfur-containing groups - 32604 5635.80 41.995 38.345 -0.131179098625655 Down 0.288337075683529 Fur2 furin 2, isoform I K01349|1|0.0|1096|dme:Dmel_CG18734|furin [EC:3.4.21.75];K08654|2|0.0|796|hsa:5125|proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-] GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559;GO:0004175//endopeptidase activity;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway 39735 1534.00 22.475 23.085 0.0386346166475567 Up 0.112798837670057 elgi early girl, isoform B K11981|1|6e-180|630|dme:Dmel_CG17033|E3 ubiquitin-protein ligase NRDP1 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0019787//small conjugating protein ligase activity GO:0051726//regulation of cell cycle;GO:0032446//protein modification by small protein conjugation 35922 3492.00 5.965 5.365 -0.152943966938706 Down 0.178708228767666 Vang Van gogh, isoform B K04510|1|0.0|981|dme:Dmel_CG8075|vang-like GO:0031224//intrinsic to membrane - GO:0032501//multicellular organismal process;GO:0001736//establishment of planar polarity 31169 1971.12 4.95 5.72 0.208586621811418 Up 0.219488838990886 CG4313 CG4313, isoform E K08421|1|1e-15|85.5|xtr:779788|G protein-coupled receptor 84;K04132|2|1e-15|85.1|xtr:100127705|muscarinic acetylcholine receptor M4;K04145|3|7e-15|82.8|dre:282557|dopamine receptor D2;K14049|5|2e-13|78.2|dme:Dmel_CG33517|dopamine D2-like receptor - - - 41126 4000.81 10.375 10.315 -0.00836751523516452 Down 0.0502575617487782 alpha-Man-II alpha mannosidase II, isoform B K01231|1|0.0|2253|dme:Dmel_CG18802|alpha-mannosidase II [EC:3.2.1.114] GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part GO:0046914//transition metal ion binding;GO:0015924 GO:0006486//protein glycosylation;GO:0019318//hexose metabolic process 36776 2223.48 117.31 134.255 0.19464981884031 Up 0.405164443270374 Ric Ras-related protein interacting with calmodulin, isoform B K07847|1|5e-137|488|dme:Dmel_CG8418|Rad and Gem related GTP binding protein 1;K07833|3|1e-64|248|oaa:100076506|Ras-like without CAAX 2 GO:0016020//membrane;GO:0016020//membrane GO:0032561//guanyl ribonucleotide binding;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction 53444 1450.10 27.31 29.37 0.104913951559565 Up 0.224772156914542 SC35 SC35, isoform D K12891|1|8e-46|184|dgr:Dgri_GH11678|splicing factor, arginine/serine-rich 2 GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0044427//chromosomal part;GO:0016607//nuclear speck;GO:0044427//chromosomal part;GO:0016607//nuclear speck GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly 318890 1653.12 29.93 0.01 -11.5473765634981 Down 0.965427288337076 p24-2 p24-related-2, isoform B K07520|1|0.0|1450|dme:Dmel_CG31352|actin-binding LIM protein GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0003002//regionalization;GO:0051234//establishment of localization;GO:0002118//aggressive behavior;GO:0051234//establishment of localization;GO:0006996//organelle organization 19835905 2669.00 89.785 106.65 0.248337620423476 Up 0.468630299828292 34031 575.00 17.85 10.675 -0.741688004408609 Down 0.610223220182274 Obp28a Odorant-binding protein 28a - - GO:0008144//drug binding;GO:0005549//odorant binding GO:0051234//establishment of localization 31160 1105.00 5.505 4.74 -0.21585550466611 Down 0.221437062475234 CG3587 CG3587 - - - - 32919 6612.00 8.47 9.105 0.10429704764464 Up 0.159820367190596 rictor rapamycin-insensitive companion of Tor, isoform C K08267|1|0.0|3425|dme:Dmel_CG8002|rapamycin-insensitive companion of mTOR - - GO:0048812//neuron projection morphogenesis;GO:0033554//cellular response to stress 3772524 546.00 0.23 0.01 -4.52356195605701 Down 0.229362039360719 CG33658 CG33658 K09255|1|3e-18|90.9|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|1e-08|59.3|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 34824 1282.00 12.615 13.17 0.0621151392802142 Up 0.128417646281865 nimC4 nimrod C4 K06825|1|4e-10|65.9|cfa:478293|fibrillin 1 GO:0016020//membrane - GO:0006909//phagocytosis 32785 12442.00 0.085 0.125 0.556393348524385 Up 0.0683529256373002 Dhc16F dynein heavy chain at 16F K10408|1|0.0|2337|hsa:25981|dynein heavy chain, axonemal GO:0030286//dynein complex GO:0003676//nucleic acid binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032559 GO:0006259//DNA metabolic process;GO:0007017//microtubule-based process;GO:0006351//transcription, DNA-dependent 12798404 601.00 0.07 0.08 0.192645077942396 Up 0.045898824461762 CG43189 CG43189 - - - - 246438 1829.00 0.06 0.035 -0.777607578663552 Down 0.0552767137762515 CG30076 CG30076 - - - - 40934 1639.60 5.03 5.26 0.064504399486775 Up 0.09047681944261 Taf7 TBP-associated factor 7, isoform B K03132|1|0.0|715|dme:Dmel_CG2670|transcription initiation factor TFIID subunit D6 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006352//DNA-dependent transcription, initiation 19835369 911.00 6.445 7.86 0.286348953896955 Up 0.315348038568221 32787 2658.00 10.085 10.33 0.0346291702520981 Up 0.0799762250693435 dik diskette, isoform C K11315|1|0.0|816|dme:Dmel_CG7098|transcriptional adapter 3 GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome GO:0004468//lysine N-acetyltransferase activity - 42823 1726.00 0.18 0.585 1.70043971814109 Up 0.239334301941619 CG13597 testis-specifically expressed bromodomain containing protein-1 K11721|1|2e-23|110|ame:551826|bromodomain-containing protein 3;K11724|3|4e-23|109|mdo:100026533|bromodomain testis-specific protein - - GO:0000377 36795 2101.67 146.9 131.375 -0.161143631706739 Down 0.3621384229296 CG8446 CG44243, isoform B K10105|1|0.0|648|dpo:Dpse_GA21085|lipoyltransferase 1 [EC:6.-.-.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0018065//protein-cofactor linkage;GO:0018065//protein-cofactor linkage 3355143 2685.00 112.095 127.91 0.19040713035047 Up 0.404239862633734 p120ctn adherens junction protein p120 K05690|1|5e-105|382|bta:515187|catenin (cadherin-associated protein), delta 1 GO:0005815//microtubule organizing center;GO:0070161 - GO:0048592//eye morphogenesis;GO:0034331 12798166 156.00 0.35 0.01 -5.12928301694497 Down 0.297120591731607 19835370 1629.58 0.015 0.09 2.58496250072116 Up 0.11075155197464 38421 2255.00 2.58 2.545 -0.0197054093475589 Down 0.0488046493197728 CG12010 CG12010 K13525|1|7e-73|275|cin:100182252|transitional endoplasmic reticulum ATPase - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 43238 1301.00 7.15 6.26 -0.191780584733134 Down 0.227843085457667 CG14252 CG14252 - - - - 37230 3037.53 85.315 87.88 0.0427354526830098 Up 0.13333773609827 hts hu li tai shao, isoform S - GO:0043232;GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal;GO:0016020//membrane;GO:0043232;GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal;GO:0016020//membrane;GO:0043232;GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal;GO:0016020//membrane;GO:0043232;GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal;GO:0016020//membrane;GO:0043232;GO:0044444//cytoplasmic part;GO:0035324//female germline ring canal;GO:0016020//membrane GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding GO:0031023//microtubule organizing center organization;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007015//actin filament organization;GO:0007283//spermatogenesis;GO:0007051//spindle organization;GO:0031023//microtubule organizing center organization;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007015//actin filament organization;GO:0007283//spermatogenesis;GO:0007051//spindle organization;GO:0031023//microtubule organizing center organization;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007015//actin filament organization;GO:0007283//spermatogenesis;GO:0007051//spindle organization;GO:0031023//microtubule organizing center organization;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007015//actin filament organization;GO:0007283//spermatogenesis;GO:0007051//spindle organization;GO:0031023//microtubule organizing center organization;GO:0007293//germarium-derived egg chamber formation;GO:0048134//germ-line cyst formation;GO:0007015//actin filament organization;GO:0007283//spermatogenesis;GO:0007051//spindle organization 36161 1546.00 0.08 0.17 1.08746284125034 Up 0.103057720248316 CG12943 polyphemus, isoform C - GO:0031224//intrinsic to membrane GO:0005275//amine transmembrane transporter activity - 40747 901.00 6.175 3.24 -0.930445323587415 Down 0.519680359265619 Obp83ef Odorant-binding protein 83ef - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 33023 1259.47 43.465 21.35 -1.02561807476747 Down 0.705719191652358 Peritrophin-A peritrophin A, isoform C K01873|1|3e-11|69.7|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding GO:0006022;GO:0006022 14462699 747.00 0.215 0.065 -1.72582503656101 Down 0.138059701492537 CG43798 CG43798 - - - - 37798 1361.17 146.44 141.665 -0.0478263112085881 Down 0.156485272751288 Nap1 nucleosome assembly protein 1, isoform C K11279|1|4e-179|627|dme:Dmel_CG5330|nucleosome assembly protein 1-like 1 GO:0005678//chromatin assembly complex GO:0005515//protein binding GO:0006351//transcription, DNA-dependent;GO:0034728//nucleosome organization 117503 1412.00 0.165 0.215 0.381870635343644 Up 0.0729758288204993 RacGAP84C Rac GTPase activating protein at 84C, isoform B K10360|1|7e-16|85.9|dre:100006612|myosin IX GO:0043231//intracellular membrane-bounded organelle;GO:0005881//cytoplasmic microtubule;GO:0043231//intracellular membrane-bounded organelle;GO:0005881//cytoplasmic microtubule GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0008289//lipid binding GO:0000278//mitotic cell cycle;GO:0007265//Ras protein signal transduction;GO:0048812//neuron projection morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0045165//cell fate commitment;GO:0035108//limb morphogenesis;GO:0051301//cell division;GO:0045185//maintenance of protein location;GO:0048592//eye morphogenesis;GO:0048232//male gamete generation;GO:0035466;GO:0000278//mitotic cell cycle;GO:0007265//Ras protein signal transduction;GO:0048812//neuron projection morphogenesis;GO:0016055//Wnt receptor signaling pathway;GO:0045165//cell fate commitment;GO:0035108//limb morphogenesis;GO:0051301//cell division;GO:0045185//maintenance of protein location;GO:0048592//eye morphogenesis;GO:0048232//male gamete generation;GO:0035466 34414 1168.70 525.33 467.515 -0.168211320836971 Down 0.387465328226126 Mdh1 malate dehydrogenase 1, isoform B K00025|1|9e-180|629|dme:Dmel_CG5362|malate dehydrogenase [EC:1.1.1.37] - GO:0016615//malate dehydrogenase activity GO:0009060//aerobic respiration;GO:0043648//dicarboxylic acid metabolic process;GO:0006007//glucose catabolic process 19836002 436.00 0.2 0.01 -4.32192809488736 Down 0.209648659358077 3771809 595.00 0.335 0.17 -0.978626349207433 Down 0.132148989565447 His2B:CG33872 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 19835823 492.00 0.255 0.01 -4.6724253419715 Down 0.24085325584467 41027 2239.34 233.005 195.365 -0.254188884689854 Down 0.48018755778629 CG8036 CG8036, isoform D K00615|1|0.0|1114|dme:Dmel_CG8036|transketolase [EC:2.2.1.1] GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part - GO:0000226//microtubule cytoskeleton organization;GO:0000226//microtubule cytoskeleton organization;GO:0000226//microtubule cytoskeleton organization 34172 3251.00 3.015 3.215 0.0926607354278627 Up 0.0923590014529124 D12 D12 K11341|1|8e-12|73.2|api:100166035|YEATS domain-containing protein 4 GO:0043231//intracellular membrane-bounded organelle - GO:0006351//transcription, DNA-dependent 33127 1785.00 8.24 3.82 -1.10907169914747 Down 0.589486197331924 Cyp6t1 Cyp6t1 K00517|1|0.0|996|dme:Dmel_CG1644| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 42214 2728.00 0.375 0.245 -0.614108846380673 Down 0.11028926165632 Vha100-4 vacuolar H[+] ATPase 100kD subunit 4 K02154|1|0.0|1621|dme:Dmel_CG7678|V-type H+-transporting ATPase subunit I [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process 43355 1243.88 5.615 6.455 0.20113107290659 Up 0.225861841236296 CG4951 CG4951, isoform B - - - - 19835603 797.00 0.06 0.06 0 - 0.0382380134724607 36933 614.00 0.915 0.735 -0.316027493447678 Down 0.118214238541804 CG15605 CG15605 - - - - 37173 1183.77 6.795 6.22 -0.127558970636789 Down 0.168636903975697 CG15082 CG15082, isoform B - - - - 35190 2520.80 152.36 180.78 0.246750885752279 Up 0.477281732928279 Ddc dopa decarboxylase, isoform D K01593|1|0.0|946|dme:Dmel_CG10697|aromatic-L-amino-acid decarboxylase [EC:4.1.1.28] - GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0007617//mating behavior;GO:0007562//eclosion;GO:0006568//tryptophan metabolic process;GO:0006584//catecholamine metabolic process;GO:0007617//mating behavior;GO:0007562//eclosion;GO:0006568//tryptophan metabolic process;GO:0006584//catecholamine metabolic process;GO:0007617//mating behavior;GO:0007562//eclosion;GO:0006568//tryptophan metabolic process;GO:0006584//catecholamine metabolic process 33904 1936.43 20.21 18.14 -0.155894865851213 Down 0.288204992735438 CG9536 CG9536, isoform B - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 40955 4800.97 10.645 13.025 0.291107422713577 Up 0.380663056399419 CG7918 muscarinic acetylcholine Receptor, B-type, isoform B K04134|1|0.0|1645|dme:Dmel_CG7918|muscarinic acetylcholine receptor, invertebrate GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060 35006 1849.72 0.27 0.255 -0.082462160191973 Down 0.0463611147800819 CG13278 pickpocket 17, isoform B - GO:0044464//cell part GO:0005261//cation channel activity GO:0030001//metal ion transport 117501 1524.00 0.68 0.74 0.12199052437861 Up 0.0636309602430326 Gr10a gustatory receptor 10a K08471|1|0.0|756|dme:Dmel_CG32664|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 39222 1640.17 10.35 14.46 0.48243678456443 Up 0.505844670453044 CG6404 CG6404, isoform B K03217|1|0.0|749|dme:Dmel_CG6404|preprotein translocase subunit YidC GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0022892;GO:0022892 GO:0034613//cellular protein localization;GO:0034613//cellular protein localization 41167 1131.04 45.82 49.63 0.115234995992445 Up 0.274204200237749 SpdS spermidine synthase, isoform C K00797|1|5e-167|587|dya:Dyak_GE25970|spermidine synthase [EC:2.5.1.16] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0006596//polyamine biosynthetic process;GO:0006596//polyamine biosynthetic process 19835740 10988.00 0.135 0.245 0.85982234195174 Up 0.107647602694492 40218 1527.00 0.29 0.065 -2.15754127698648 Down 0.176198652753929 CG13813 CG13813 - - - - 37618 2632.13 0.54 1.13 1.06529146025172 Up 0.270836085061419 CycB cyclin B, isoform E K05868|1|0.0|864|dme:Dmel_CG3510|cyclin B GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044427//chromosomal part;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm;GO:0044430//cytoskeletal part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044427//chromosomal part;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm;GO:0044430//cytoskeletal part;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044427//chromosomal part;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm;GO:0044430//cytoskeletal part GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity;GO:0019887//protein kinase regulator activity GO:0000070//mitotic sister chromatid segregation;GO:0033205//cell cycle cytokinesis;GO:0033554//cellular response to stress;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051313;GO:0000090//mitotic anaphase;GO:0009792//embryo development ending in birth or egg hatching;GO:0000070//mitotic sister chromatid segregation;GO:0033205//cell cycle cytokinesis;GO:0033554//cellular response to stress;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051313;GO:0000090//mitotic anaphase;GO:0009792//embryo development ending in birth or egg hatching;GO:0000070//mitotic sister chromatid segregation;GO:0033205//cell cycle cytokinesis;GO:0033554//cellular response to stress;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0051313;GO:0000090//mitotic anaphase;GO:0009792//embryo development ending in birth or egg hatching 19835741 387.00 1.23 1.97 0.679537314117136 Up 0.277010962884692 42101 704.00 15.24 3.745 -2.02482527903457 Down 0.722559767534011 Eh eclosion hormone, isoform B - - - - 37458 1061.08 215.075 273.73 0.347913720717713 Up 0.571027605336151 CG10433 CG10433, isoform C - - - - 42542 2277.00 0.055 0.055 0 - 0.0382380134724607 lbe ladybird early K09353|1|2e-59|230|dpo:Dpse_GA19692|homeobox protein LBX GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006351//transcription, DNA-dependent;GO:0048812//neuron projection morphogenesis;GO:0014706//striated muscle tissue development;GO:0010468//regulation of gene expression;GO:0001708//cell fate specification;GO:0048870//cell motility;GO:0000768//syncytium formation by plasma membrane fusion;GO:0050767//regulation of neurogenesis;GO:0007560//imaginal disc morphogenesis 38154 690.51 398.87 370.97 -0.104616096687667 Down 0.264463082816008 mtacp1 mitochondrial acyl carrier protein 1, isoform C K03955|1|7e-75|280|dsi:Dsim_GD13611|NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 [EC:1.6.5.3 1.6.99.3] - GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892 GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process 35305 1549.00 44.99 42.08 -0.0964696622867436 Down 0.237088891824066 La La autoantigen-like K11090|1|2e-172|605|dme:Dmel_CG10922|lupus La protein GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0008097//5S rRNA binding;GO:0003715 GO:0010467//gene expression 40215 1092.00 0.295 0.085 -1.7951802081115 Down 0.167481178179897 CG17145 CG17145, isoform B - - GO:0030247//polysaccharide binding GO:0006022 36469 2251.00 3.545 1.02 -1.79721647526802 Down 0.54078061022322 CG4712 CG4712, isoform B - - - - 38548 923.00 40.98 7.275 -2.4939008312156 Down 0.783152819970942 CG11345 CG11345 - GO:0005576//extracellular region - - 41447 2361.92 37.335 38.69 0.0514319977410244 Up 0.142979791308942 CG12213 CG12213, isoform E K05762|1|2e-06|54.7|cin:445597|radixin;K10362|2|3e-06|53.9|phu:Phum_PHUM607810|myosin XVIII;K06636|3|8e-06|52.4|bmy:Bm1_12960|structural maintenance of chromosome 1 - - - 32090 3536.57 7.625 7.43 -0.0373751267990148 Down 0.080768722757892 HP5 heterochromatin protein 5, isoform C - GO:0044427//chromosomal part;GO:0044427//chromosomal part - - 5740475 770.03 24.755 23.915 -0.0498041579758555 Down 0.131983885880333 CG41378 CG41378, isoform E K08059|1|2e-16|85.9|ecb:100070878|interferon, gamma-inducible protein 30 - - - 38846 4041.60 94.03 112.25 0.255522421933967 Up 0.47949412230881 lqf liquid facets, isoform L K12471|1|0.0|1345|dsi:Dsim_GD14024|epsin - - GO:0007219//Notch signaling pathway;GO:0042685//cardioblast cell fate specification;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0042685//cardioblast cell fate specification;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0042685//cardioblast cell fate specification;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0042685//cardioblast cell fate specification;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0042685//cardioblast cell fate specification;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0042685//cardioblast cell fate specification;GO:0006897//endocytosis 37580 573.18 957.67 934.435 -0.0354342960801695 Down 0.140305111610091 RpS16 ribosomal protein S16, isoform B K02960|1|1e-68|258|dya:Dyak_GE13998|small subunit ribosomal protein S16e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 34760 737.00 0.01 0.19 4.24792751344359 Up 0.201558578787479 CG16956 CG16956 - - - - 33521 1391.44 17.205 20.16 0.228667746762935 Up 0.368775591071193 CG17221 CG17221, isoform C K10133|1|6e-10|65.5|dre:796473|tumor protein p53-inducible protein 3 [EC:1.-.-.-] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0048037//cofactor binding;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0048037//cofactor binding GO:0007420//brain development;GO:0008152//metabolic process;GO:0007420//brain development;GO:0008152//metabolic process 43239 1587.00 0.31 0.85 1.45519462575083 Up 0.27258618412363 CG18472 CG18472 K09553|1|9e-15|81.6|cin:100181490|stress-induced-phosphoprotein 1 - - - 39510 876.00 0.055 0.9 4.03242147769238 Up 0.405989961695945 CG10725 CG10725 K01873|1|6e-20|97.8|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K01183|5|6e-10|64.7|dme:Dmel_CG18140|chitinase [EC:3.2.1.14] - GO:0030247//polysaccharide binding GO:0006022 44728 1694.30 8.575 11.62 0.438401492344354 Up 0.460804385153877 MED6 mediator complex subunit 6, isoform E - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0003712//transcription cofactor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent;GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 37315 1626.00 0.14 0.11 -0.347923303420307 Down 0.0607911768590675 CG13423 CG13423 K01376|1|0.0|962|dme:Dmel_CG13423| [EC:3.4.22.-];K01372|2|5e-73|275|ame:724901|bleomycin hydrolase [EC:3.4.22.40] - - - 40701 2267.00 2.91 2.595 -0.165284614550403 Down 0.135451063267732 Rab23 Rab23 K06234|1|5e-140|498|dme:Dmel_CG2108|Ras-related protein Rab-23 GO:0016020//membrane;GO:0044424//intracellular part GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0006810//transport;GO:0002009//morphogenesis of an epithelium 43584 965.00 18.745 17.175 -0.126195726582628 Down 0.243957205124818 CG15529 CG15529 K07371|1|3e-07|55.8|mmu:17060|B-cell linker - GO:0005488//binding - 50253 1490.32 12.92 15.28 0.242038473341824 Up 0.352925637300225 CG12821 Autophagy-specific gene 10, isoform D K01669|1|5e-71|270|dme:Dmel_CG18853|deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] - - - 35817 543.00 5.645 1.005 -2.48977807959407 Down 0.652819970941751 Lcp1 larval cuticle protein 1, isoform B K10955|1|3e-06|50.8|mcc:720903|intestinal mucin-2 - GO:0042302//structural constituent of cuticle - 44915 1753.00 0.855 1.05 0.296393002780225 Up 0.121780478140272 DNApol-alpha60 DNA polymerase alpha 60kD K02685|1|0.0|1045|dme:Dmel_CG5553|DNA primase large subunit [EC:2.7.7.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003899//DNA-directed RNA polymerase activity;GO:0034061 GO:0006260//DNA replication;GO:0048592//eye morphogenesis;GO:0051320//S phase 318153 3600.00 0.515 1.08 1.06838697498025 Up 0.266279223352265 CG32686 CG32686, isoform B - - - - 42810 1438.21 164.825 52.94 -1.63850498141381 Down 0.772057852331264 Lsd-1 lipid storage droplet-1, isoform D K08768|1|4e-06|53.1|dre:100001938|perilipin GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - - 53432 3554.00 0.38 0.57 0.584962500721156 Up 0.13218201030247 ACXA ACXA, isoform H K01768|1|0.0|2113|dme:Dmel_CG17176|adenylate cyclase [EC:4.6.1.1];K03458|3|0.0|992|der:Dere_GG23802|nucleobase:cation symporter-2, NCS2 family GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process;GO:0048232//male gamete generation 19835716 871.00 1.46 1.49 0.0293439615821445 Up 0.0473517368907674 41624 935.00 1.785 1.715 -0.0577154978562877 Down 0.0598996169594505 CG8476 CG8476 K09515|1|2e-11|69.7|gga:417783|DnaJ homolog subfamily B member 9;K09504|4|8e-11|67.8|nve:NEMVE_v1g120890|DnaJ homolog subfamily A member 3 - - - 34611 1559.47 5.345 5.835 0.126542707986858 Up 0.156419231277242 escl escl, isoform C K11462|1|0.0|853|dsi:Dsim_GD23804|polycomb protein EED - GO:0008276//protein methyltransferase activity GO:0034968//histone lysine methylation;GO:0010467//gene expression 32488 1217.94 13.775 15.39 0.15994091286969 Up 0.26911900673623 CG7860 CG7860, isoform B K13051|1|3e-170|598|dme:Dmel_CG7860|beta-aspartyl-peptidase (threonine type) [EC:3.4.19.5] GO:0044424//intracellular part GO:0004067//asparaginase activity GO:0048102//autophagic cell death;GO:0006530//asparagine catabolic process 50157 731.45 0.185 0.725 1.97045572438598 Up 0.284044379870559 CG12589 CG12589, isoform C - - - - 3772359 723.00 1.15 1.77 0.622115499138622 Up 0.249042398626337 CG33704 CG33704 - - - - 12798145 338.00 0.01 0.15 3.90689059560852 Up 0.171410645885616 HP1Lcsd heterochromatin protein 1L chromoshadow domain - - - - 36270 1807.00 133.62 113.895 -0.230431549955949 Down 0.45215295205389 ERp60 ERp60 K08056|1|0.0|955|dme:Dmel_CG8983|protein disulfide isomerase family A, member 3 [EC:5.3.4.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0003824//catalytic activity GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis 34979 1441.81 50.87 96.165 0.918696815239495 Up 0.712851670849293 Idgf2 imaginal disc growth factor 2, isoform C K01183|1|3e-41|169|dme:Dmel_CG18140|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0070851//growth factor receptor binding;GO:0043167//ion binding GO:0048513//organ development;GO:0006026 36999 5220.51 19.73 20.53 0.0573426713850433 Up 0.142055210672302 lack lethal with a checkpoint kinase, isoform B K04678|1|0.0|1712|dme:Dmel_CG4943|E3 ubiquitin ligase SMURF1/2 [EC:6.3.2.19] - - - 45973 6581.00 0.05 0.11 1.13750352374994 Up 0.0858869369964338 fs(1)N female sterile (1) nasrat K00670|1|4e-138|493|dse:Dsec_GM19126|peptide alpha-N-acetyltransferase [EC:2.3.1.88] GO:0030312//external encapsulating structure;GO:0045171//intercellular bridge;GO:0009986//cell surface;GO:0044424//intracellular part GO:0016407//acetyltransferase activity GO:0030703//eggshell formation;GO:0000578//embryonic axis specification 39523 1346.00 11.32 9.43 -0.263544282156786 Down 0.338264430062079 Vps36 vacuolar protein sorting 36 K12190|1|0.0|741|dme:Dmel_CG10711|ESCRT-II complex subunit VPS36 - - GO:0006915//apoptotic process;GO:0007219//Notch signaling pathway 47065 1817.00 101.83 63.165 -0.688965373148875 Down 0.677981772553163 qsm quasimodo, isoform B - - - - 31434 16098.06 4.4 4.855 0.141967771894533 Up 0.155032360322282 CG15465 CG15465, isoform B - - - - 35199 1521.00 0.01 0.04 2 Up 0.0694426099590543 gammaTub37C gamma-Tubulin at 37C, isoform B K10389|1|0.0|914|dsi:Dsim_GD21771|tubulin gamma GO:0000931//gamma-tubulin large complex GO:0017111//nucleoside-triphosphatase activity;GO:0008017//microtubule binding;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0000278//mitotic cell cycle;GO:0043623//cellular protein complex assembly;GO:0051297//centrosome organization;GO:0051304//chromosome separation 31808 2140.00 25.885 32.895 0.345751994533822 Up 0.510500594373266 Hexo2 hexosaminidase 2 K12373|1|0.0|1214|dme:Dmel_CG1787|beta-hexosaminidase [EC:3.2.1.52] GO:0016020//membrane GO:0043167//ion binding;GO:0004563//beta-N-acetylhexosaminidase activity GO:0044238//primary metabolic process 40121 771.00 5.58 0.73 -2.93429675294917 Down 0.672764496103553 Cpr76Bb cuticular protein 76Bb - - GO:0042302//structural constituent of cuticle - 43785 1580.46 92.955 72.715 -0.354279468112573 Down 0.555012547880069 Rad23 Rad23, isoform C K10839|1|0.0|749|dme:Dmel_CG1836|UV excision repair protein RAD23 - - - 5740186 467.00 7.94 7.8 -0.0256648833933471 Down 0.0680227182670717 CG34265 CG34265 - - - - 36147 5281.81 34.68 34.87 0.00788246555486977 Up 0.0605600316999075 CG30015 CG30015, isoform G - - - - 43678 2764.00 0.045 0.13 1.53051471669878 Up 0.0999207502311452 CG11318 CG11318 K12839|1|1e-68|261|dmo:Dmoj_GI23624|survival of motor neuron-related-splicing factor 30;K08455|2|4e-25|117|oaa:100083687|G protein-coupled receptor 112 GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway 34017 1033.04 82.62 78.585 -0.0722370974659046 Down 0.192742042002377 CG5177 CG5177, isoform B K01087|1|7e-149|526|dme:Dmel_CG5177|trehalose-phosphatase [EC:3.1.3.12] - - GO:0005991//trehalose metabolic process 3772478 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 43083 1803.00 38.175 36.725 -0.0558656662405714 Down 0.160183595297847 CG5112 CG5112 K01426|1|3e-74|279|dpo:Dpse_GA20671|amidase [EC:3.5.1.4];K01175|3|9e-26|118|mdo:100023944| [EC:3.1.-.-] GO:0044444//cytoplasmic part GO:0016879//ligase activity, forming carbon-nitrogen bonds - 31366 4278.00 0.035 0.035 0 - 0.0382380134724607 CG15570 CG15570 - - - - 3772180 3627.81 62.42 75.13 0.267380745008177 Up 0.479593184519878 Sxl Sex lethal, isoform Z K13208|1|1e-45|184|dre:30065|ELAV like protein 2/3/4 GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0005102//receptor binding;GO:0030371//translation repressor activity;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic;GO:0007166//cell surface receptor signaling pathway;GO:0007542;GO:0007444//imaginal disc development;GO:0006412//translation;GO:0006310//DNA recombination;GO:0033119//negative regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0007292//female gamete generation;GO:0018993//somatic sex determination;GO:0040029//regulation of gene expression, epigenetic 35295 1533.32 21.32 19.985 -0.0932898653387291 Down 0.194194954431383 CG10747 CG10747, isoform B - - GO:0009975//cyclase activity;GO:0004620//phospholipase activity;GO:0042578//phosphoric ester hydrolase activity GO:0023033;GO:0006644//phospholipid metabolic process 37126 6569.24 26.135 31.405 0.265011110040248 Up 0.439737154933298 CG30116 CG30116, isoform D K11887|1|0.0|1205|ame:409686|proteasomal ATPase-associated factor 1;K03130|2|1e-25|120|dgr:Dgri_GH20712|transcription initiation factor TFIID subunit D4;K10260|5|2e-25|119|api:100166211|F-box and WD-40 domain protein 7 - - - 317885 4185.19 0.075 0.15 1 Up 0.0917316074494783 CG32152 CG32152, isoform C K11434|1|1e-54|214|nve:NEMVE_v1g179399|protein arginine N-methyltransferase 1 [EC:2.1.1.-];K11439|3|3e-53|209|dre:564110|protein arginine N-methyltransferase 8 [EC:2.1.1.-] GO:0044424//intracellular part GO:0008168//methyltransferase activity GO:0008213 39425 1023.72 12.52 11.76 -0.090346502096254 Down 0.165037643640206 CG10681 CG10681, isoform B - - - - 35231 1215.00 9.41 10.145 0.108502237028122 Up 0.175009906221107 CG10194 CG10194 K13355|1|0.0|689|dme:Dmel_CG10194|nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-] - GO:0003824//catalytic activity GO:0006909//phagocytosis 34802 867.00 0.545 0.355 -0.618437205272245 Down 0.132974507991018 CG7968 CG7968 - - - - 19835179 525.00 0.39 0.28 -0.478047296804644 Down 0.0999867917051909 40127 5404.00 15.38 14.635 -0.0716327575530761 Down 0.148064984810461 l(3)76BDr l(3)76BDr - - GO:0046914//transition metal ion binding - 19835418 1167.00 9.22 9.775 0.084329951765377 Up 0.14109760929864 31620 6247.08 12.635 13.92 0.139733546903953 Up 0.238211596882842 pod1 pod1, isoform G K13882|1|9e-65|249|xtr:448298|coronin-1A - - - 318765 921.00 0.735 0.285 -1.36678233067162 Down 0.244947827235504 CG31493 CG31493, isoform B - - GO:0016407//acetyltransferase activity;GO:0016407//acetyltransferase activity - 34097 655.00 5.715 4.53 -0.335242448168243 Down 0.306135252938846 CG7429 CG7429 - - - - 31518 3014.00 2.525 2.505 -0.0114727844439487 Down 0.0432901862369568 mof males absent on the first K11308|1|0.0|1412|dme:Dmel_CG3025|histone acetyltransferase MYST1 [EC:2.3.1.48] - - - 19835017 1043.00 0.04 0.085 1.08746284125034 Up 0.0796790384361379 19834921 633.00 0.14 0.175 0.321928094887362 Up 0.0662726192048606 37632 1918.00 13.225 15.885 0.264397367712104 Up 0.376469422797517 CG13532 CG13532 - - - - 34660 2962.65 5.675 5.935 0.0646276374636295 Up 0.0956940958922203 Oatp33Ea organic anion transporting polypeptide 33Ea, isoform B - GO:0044464//cell part GO:0008509//anion transmembrane transporter activity GO:0006820//anion transport 32760 4849.92 18.235 18.03 -0.0163108029037706 Down 0.0696077136441685 Socs16D suppressor of cytokine signaling at 16D, isoform B K04700|1|0.0|1364|dme:Dmel_CG8146|suppressor of cytokine signaling, invertebrate - GO:0005488//binding - 34541 4752.37 11.295 14.125 0.322566596796828 Up 0.415499933958526 Ge-1 Ge-1 ortholog, isoform B K12616|1|0.0|2303|dme:Dmel_CG6181|enhancer of mRNA-decapping protein 4 GO:0030529//ribonucleoprotein complex;GO:0030529//ribonucleoprotein complex - - 34055 697.44 4271.38 2795.3 -0.611699126185054 Down 0.68141592920354 CG7203 CG7203, isoform C - - - - 37390 1448.00 0.325 0.44 0.437063805608843 Up 0.103156782459384 Cht8 Cht8 K01183|1|0.0|959|dme:Dmel_CG9357|chitinase [EC:3.2.1.14] - - - 33068 813.00 0.295 0.65 1.13972476366661 Up 0.211629903579448 I-3 Inhibitor-3 - - - - 7354378 1540.00 8.12 10.95 0.43137923730336 Up 0.447397965922599 tal-3A tal-3A - - - - 42726 1202.00 13.825 12.095 -0.192868711142145 Down 0.295106326773214 Ublcp1 Ubiquitin-like domain-containing C-terminal domain phosphatase 1 K01090|1|1e-180|632|dme:Dmel_CG6697|protein phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0016791//phosphatase activity - 41728 1761.00 73.195 59.565 -0.297280238816798 Down 0.509939241843878 CG31326 CG31326 K01316|1|3e-30|133|mmu:19146|protease, serine, 7 (enterokinase) [EC:3.4.21.9] - - - 3772397 353.00 4.26 4.95 0.216575094741134 Up 0.210705322942808 31339 6721.56 5.78 3.68 -0.651363726443666 Down 0.437821952185973 ec echinus, isoform C - - GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity GO:0070646//protein modification by small protein removal;GO:0046666//retinal cell programmed cell death;GO:0007389//pattern specification process;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0046666//retinal cell programmed cell death;GO:0007389//pattern specification process;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0046666//retinal cell programmed cell death;GO:0007389//pattern specification process;GO:0019941//modification-dependent protein catabolic process 19835461 801.00 0.055 0.06 0.125530882083859 Up 0.0382380134724607 42759 541.72 695.83 659.37 -0.0776466318242758 Down 0.225465592392022 ATPsyn-Cf6 ATPase coupling factor 6, isoform C K02131|1|4e-54|210|dme:Dmel_CG4412|F-type H+-transporting ATPase subunit 6 [EC:3.6.3.14] GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 248194 1245.53 62.705 42.015 -0.57767600175819 Down 0.642418438779554 Gclm Glutamate-cysteine ligase modifier subunit, isoform B K11205|1|8e-142|503|dme:Dmel_CG4919|glutamate--cysteine ligase regulatory subunit GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0019899//enzyme binding;GO:0003824//catalytic activity GO:0008306//associative learning;GO:0035227;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process 34903 2273.00 2.03 0.59 -1.78269286782333 Down 0.441289129573372 esg escargot K09218|1|0.0|721|dme:Dmel_CG3758|snail, invertebrate GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007635//chemosensory behavior;GO:0006355//regulation of transcription, DNA-dependent;GO:0048073//regulation of eye pigmentation;GO:0035153//epithelial cell type specification, open tracheal system;GO:0007399//nervous system development;GO:0019827//stem cell maintenance;GO:0035146 12797941 625.31 6.285 6.63 0.0770961256920799 Up 0.114747061154405 50055 411.17 119.355 123.225 0.0460359761804932 Up 0.155197464007397 CG5791 CG5791, isoform B - - - - 34791 2063.22 45.645 28.685 -0.670160316583783 Down 0.649385814291375 b black, isoform C K01580|1|0.0|1083|dme:Dmel_CG7811|glutamate decarboxylase [EC:4.1.1.15] - GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0008652//cellular amino acid biosynthetic process;GO:0007444//imaginal disc development;GO:0035110;GO:0007610//behavior;GO:0006208//pyrimidine nucleobase catabolic process 41770 4040.53 18.61 14.375 -0.372516099340052 Down 0.47695152555805 stumps stumps, isoform F K12230|1|2e-19|99.0|bfo:BRAFLDRAFT_118043|phosphoinositide 3-kinase adapter protein 1 - - - 12798270 897.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 CG43116 CG43116 - - - - 41528 1194.00 2.045 2.335 0.191321706767913 Up 0.131356491876899 Sas sialic acid phosphate synthase K05304|1|0.0|710|dme:Dmel_CG5232|sialic acid synthase [EC:2.5.1.56 2.5.1.57] - - - 37221 2914.55 8.49 6.08 -0.481693230109453 Down 0.434949148064985 CG11961 CG11961, isoform C - - - - 35512 6367.77 7.105 7.04 -0.0132592206054832 Down 0.0513802668075551 gp210 Gp210 ortholog, isoform B K12495|1|1e-101|372|cfa:484632|IQ motif and SEC7 domain-containing protein - - - 37024 1202.00 0.195 0.29 0.572578776265324 Up 0.0934156650376436 CG10931 CG10931 K01062|1|6e-36|151|dvi:Dvir_GJ21422|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - - - 7354466 4832.19 27.305 27.09 -0.0114047632722494 Down 0.0612864879144102 CG42342 CG42342, isoform T K06236|1|1e-17|93.2|gga:374046|collagen, type I/II/III/V/XI, alpha - - - 34718 2504.73 37.215 46.215 0.31247694714692 Up 0.500264165896183 kek4 kekkon4, isoform C K07523|1|3e-42|173|dme:Dmel_CG4192|netrin-G1 ligand;K06850|2|2e-16|87.8|tgu:100223926|slit 3 - - - 42871 3538.00 1.77 1.72 -0.0413407953808996 Down 0.0540219257693832 Apc2 adenomatous polyposis coli tumor suppressor homolog 2 K02085|1|0.0|1960|dme:Dmel_CG6193|adenomatosis polyposis coli protein GO:0044448//cell cortex part;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0070161;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0032155 GO:0015631//tubulin binding GO:0000278//mitotic cell cycle;GO:0048699//generation of neurons;GO:0007155//cell adhesion;GO:0016055//Wnt receptor signaling pathway;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0030162//regulation of proteolysis;GO:0006355//regulation of transcription, DNA-dependent;GO:0030902//hindbrain development;GO:0008363//larval chitin-based cuticle development;GO:0051301//cell division;GO:0003002//regionalization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006935//chemotaxis;GO:0035466;GO:0007293//germarium-derived egg chamber formation 32528 2559.00 0.46 0.74 0.685891409571937 Up 0.165103685114252 Efhc1.1 EFHC1 homologue 1 - - - - 5740328 765.00 113.395 117.215 0.0478001752295818 Up 0.155065381059305 43828 3400.93 269 308.415 0.197266760756895 Up 0.426495839387135 CaMKII Calcium/calmodulin-dependent protein kinase II, isoform M K04515|1|0.0|1034|dse:Dsec_GM13012|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0043234//protein complex;GO:0044456//synapse part;GO:0043005//neuron projection;GO:0016020//membrane;GO:0043234//protein complex;GO:0044456//synapse part;GO:0043005//neuron projection;GO:0016020//membrane;GO:0043234//protein complex;GO:0044456//synapse part;GO:0043005//neuron projection;GO:0016020//membrane GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0032559 GO:0048741//skeletal muscle fiber development;GO:0007613//memory;GO:0007267//cell-cell signaling;GO:0060491//regulation of cell projection assembly;GO:0007619//courtship behavior;GO:0006464//cellular protein modification process;GO:0048741//skeletal muscle fiber development;GO:0007613//memory;GO:0007267//cell-cell signaling;GO:0060491//regulation of cell projection assembly;GO:0007619//courtship behavior;GO:0006464//cellular protein modification process;GO:0048741//skeletal muscle fiber development;GO:0007613//memory;GO:0007267//cell-cell signaling;GO:0060491//regulation of cell projection assembly;GO:0007619//courtship behavior;GO:0006464//cellular protein modification process 40713 2005.96 212.765 228.595 0.103533002242857 Up 0.262019548276318 CG2082 CG2082, isoform O - - - - 50129 1615.32 0.265 0.73 1.46190410431682 Up 0.250792497688548 CG30222 CG30222, isoform G - - - - 37694 1134.00 0.21 0.83 1.98272200856816 Up 0.304484216087703 CG9863 CG9863 - - - - 12797937 724.00 1.235 1.055 -0.227268042877493 Down 0.107218333113195 CG43049 CG43049, isoform B - - - - 37956 1647.00 1.055 0.31 -1.76690287832031 Down 0.328556333377361 spz6 spatzle 6 - - - - 32846 2927.65 23.76 25.145 0.0817367172780187 Up 0.183859463743231 Bx beadex, isoform F K09371|1|3e-26|120|spu:585635|LIM homeobox transcription factor 1;K09374|2|7e-26|119|gga:373940|LIM homeobox protein 3/4;K09373|3|9e-26|119|nve:NEMVE_v1g98128|LIM homeobox protein 2/9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0007626//locomotory behavior;GO:0035110;GO:0014073;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0007626//locomotory behavior;GO:0035110;GO:0014073;GO:0007472//wing disc morphogenesis;GO:0006909//phagocytosis;GO:0002118//aggressive behavior;GO:0007626//locomotory behavior;GO:0035110;GO:0014073 14462503 593.44 0.485 1.08 1.15497465997634 Up 0.276284506670189 10178945 702.00 0.68 1.39 1.03147823147317 Up 0.296757363624356 CG42710 CG42710 - - - - 32264 3537.00 3.985 2.345 -0.764991801475095 Down 0.409787346453573 CG32645 CG32645 K00680|1|4e-27|124|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 42194 1342.00 0.235 0.305 0.376148485885249 Up 0.0819904900277374 CG7142 CG7142 K01312|1|6e-32|138|bfo:BRAFLDRAFT_88359|trypsin [EC:3.4.21.4];K09632|2|5e-29|129|mdo:100021711|chymotrypsin-like protease [EC:3.4.21.-];K01317|3|5e-29|129|ssc:397098|acrosin [EC:3.4.21.10] - - - 36240 2465.00 1.365 1.025 -0.413277041414407 Down 0.170023774930656 en engrailed, isoform B K09319|1|0.0|647|dme:Dmel_CG9015|homeobox protein engrailed GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0007365//periodic partitioning;GO:0010468//regulation of gene expression;GO:0035161;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0021537//telencephalon development;GO:0035287//head segmentation;GO:0007484//imaginal disc-derived genitalia development;GO:0007386//compartment pattern specification;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0007365//periodic partitioning;GO:0010468//regulation of gene expression;GO:0035161;GO:0001709//cell fate determination;GO:0006935//chemotaxis;GO:0021537//telencephalon development;GO:0035287//head segmentation;GO:0007484//imaginal disc-derived genitalia development;GO:0007386//compartment pattern specification 38358 1040.00 0.375 0.265 -0.500898235932682 Down 0.100548144234579 CG32487 CG32487 K01101|1|4e-96|351|dvi:Dvir_GJ11756|4-nitrophenyl phosphatase [EC:3.1.3.41] - GO:0042578//phosphoric ester hydrolase activity - 41313 1346.00 41.8 53.375 0.35266122242697 Up 0.536454893673227 Sodh-2 sorbitol dehydrogenase-2 K00008|1|0.0|699|dme:Dmel_CG4649|L-iditol 2-dehydrogenase [EC:1.1.1.14] - GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046914//transition metal ion binding GO:0008152//metabolic process 32166 708.05 7.97 7.72 -0.0459788767223913 Down 0.0905758816536785 Chrac-16 chromatin accessibility complex 16kD protein, isoform B K11656|1|8e-61|233|dme:Dmel_CG15736|chromatin accessibility complex protein 1 GO:0016585//chromatin remodeling complex GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0033554//cellular response to stress 45040 1329.00 198.68 170.25 -0.222791853650442 Down 0.446803592656188 Spn43Ab serpin 43Ab K13963|1|1e-51|204|dse:Dsec_GM21844|serpin B - GO:0004866//endopeptidase inhibitor activity - 19836057 543.00 0.63 2.04 1.69514541847158 Up 0.435147272487122 37311 557.00 345.985 188.325 -0.877484962592959 Down 0.722262580900806 Obp57c Odorant-binding protein 57c - - - - 2768721 693.00 2.24 3.475 0.633514245553266 Up 0.350944393078854 CheB42a chemosensory protein B 42a - GO:0044421//extracellular region part - GO:0010033//response to organic substance;GO:0007619//courtship behavior;GO:0009593//detection of chemical stimulus 36900 567.00 0.145 0.325 1.16438681790088 Up 0.145357284374587 Vha16-4 vacuolar H[+] ATPase 16kD subunit 4 K02155|1|2e-54|211|dme:Dmel_CG9013|V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14] - - - 35516 1200.00 0.135 0.08 -0.754887502163469 Down 0.0813630960243033 Or42b odorant receptor 42b K08471|1|0.0|807|dme:Dmel_CG12754|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 36076 3275.12 33.66 57.045 0.761065263021799 Up 0.6781798969753 Hdc histidine decarboxylase, isoform D K01590|1|0.0|1540|dme:Dmel_CG3454|histidine decarboxylase [EC:4.1.1.22] GO:0044424//intracellular part GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0048675//axon extension;GO:0009996//negative regulation of cell fate specification;GO:0009266//response to temperature stimulus;GO:0043436;GO:0035194//posttranscriptional gene silencing by RNA;GO:0060446//branching involved in open tracheal system development;GO:0001751//compound eye photoreceptor cell differentiation;GO:0035146 32123 3276.40 38.65 39.705 0.0388522814043451 Up 0.123860784572712 Amun amun, isoform L - - - - 19835227 1236.88 12.005 9.445 -0.346012701842047 Down 0.413419627526086 32526 3205.00 0.975 1.14 0.225559700415131 Up 0.104444591203276 CG33172 CG33172 K10342|1|4e-06|53.9|xtr:100145242|WD repeat and SOCS box-containing protein 2;K03130|2|6e-06|53.5|dre:334055|transcription initiation factor TFIID subunit D4 - - - 40859 2802.00 1.465 1.655 0.17593055238497 Up 0.106161669528464 Sas-4 spindle assembly abnormal 4 ortholog K11502|1|0.0|1498|dme:Dmel_CG10061|centromere protein J - - - 36744 1137.00 0.175 0.17 -0.0418201756946269 Down 0.0382380134724607 CG12970 CG12970 - - - - 42563 530.00 4.625 3.36 -0.460992132624914 Down 0.33502839783384 RpI12 RpI12 K03000|1|1e-68|259|dme:Dmel_CG13418|DNA-directed RNA polymerase I subunit A12 [EC:2.7.7.6] GO:0044452 GO:0004672//protein kinase activity;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity;GO:0032559 GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0006464//cellular protein modification process 39243 614.00 30.61 30.74 0.00611412016377986 Up 0.0570268128384626 CG6272 CG6272, isoform B K10049|1|7e-08|56.6|xla:734420|CCAAT/enhancer binding protein (C/EBP), gamma;K10052|3|1e-06|52.4|ame:411207|CCAAT/enhancer binding protein (C/EBP), invertebrate;K10048|4|4e-06|50.8|mdo:100023065|CCAAT/enhancer binding protein (C/EBP), beta GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0006351//transcription, DNA-dependent 31843 4970.32 4.4 5.885 0.419538891513784 Up 0.352133139611676 fend forked end, isoform C - - - GO:0007411//axon guidance 31028 1802.00 0.32 0.33 0.0443941193584534 Up 0.0418702945449742 CG13359 CG13359 - - - - 34396 1224.00 39.545 30.52 -0.373740332242064 Down 0.53556333377361 SamDC S-adenosylmethionine decarboxylase K01611|1|0.0|716|dme:Dmel_CG5029|S-adenosylmethionine decarboxylase [EC:4.1.1.50] - GO:0016831//carboxy-lyase activity GO:0006596//polyamine biosynthetic process 42041 494.00 1 0.935 -0.0969617298870879 Down 0.061352529388456 VhaM9.7-d vacuolar H[+] ATPase M9.7 subunit d K02153|1|2e-47|187|dme:Dmel_CG14909|V-type H+-transporting ATPase subunit H [EC:3.6.3.14] - - - 43611 2317.19 15.55 15.775 0.0207254248519464 Up 0.0708625016510369 CG2218 CG2218, isoform B K10600|1|0.0|818|dme:Dmel_CG2218|U-box domain-containing protein 5 GO:0043234//protein complex GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation 32853 2298.00 5.455 5.425 -0.00795605899176534 Down 0.0453704926693964 Ing3 Ing3 K11319|1|9e-141|501|dme:Dmel_CG6632|inhibitor of growth protein 3 - GO:0046914//transition metal ion binding - 40147 3078.49 12.035 13.44 0.159296996304263 Up 0.257660810989301 CG8765 CG8765, isoform C K09427|1|3e-09|64.7|dpo:Dpse_GA13983|Adh transcription factor 1 - - - 32912 1615.00 6.555 6.18 -0.0849889423173797 Down 0.119039756967376 Mur18B mucin related 18B - - GO:0030247//polysaccharide binding GO:0006022 40258 1907.27 15.325 12.695 -0.271626678930638 Down 0.381224408928807 CG5262 CG5262, isoform B - GO:0031224//intrinsic to membrane - - 35999 1123.00 7.55 5.965 -0.339954506517213 Down 0.346420552106723 CG1773 CG1773 K01362|1|4e-26|119|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|2|8e-26|117|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4];K09632|5|3e-23|109|gga:427531|chymotrypsin-like protease [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42373 949.00 133.035 185.27 0.477823438303307 Up 0.631752740721173 Xport exit protein of rhodopsin and TRP - - - - 43454 639.00 0.84 0.745 -0.173148902316599 Down 0.0781600845330868 CG14515 CG14515 - - - - 19835468 371.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 10178874 866.00 1.44 1.515 0.0732489820306388 Up 0.0633007528728041 32087 1639.95 1127.655 887.4 -0.34566929216077 Down 0.577433628318584 Gs2 glutamine synthetase 2, isoform F K01915|1|0.0|776|dya:Dyak_GE15935|glutamine synthetase [EC:6.3.1.2] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016211;GO:0032559;GO:0016211;GO:0032559;GO:0016211;GO:0032559 GO:0043112//receptor metabolic process;GO:0006541//glutamine metabolic process;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0043112//receptor metabolic process;GO:0006541//glutamine metabolic process;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process;GO:0043112//receptor metabolic process;GO:0006541//glutamine metabolic process;GO:0007399//nervous system development;GO:0006536//glutamate metabolic process 39069 1651.49 19.33 20.465 0.0823170292318491 Up 0.176066569805838 CG4452 CG4452, isoform E - - - - 40898 1426.00 1.575 1.78 0.176525412579119 Up 0.108274996697926 CG1287 CG1287 - GO:0016020//membrane - - 43389 1180.00 0.275 0.295 0.101283335837181 Up 0.0473847576277902 CG14062 CG14062 - - GO:0043169//cation binding;GO:0003824//catalytic activity - 39414 2165.00 0.81 0.84 0.0524674198941355 Up 0.0483423590014529 Smyd4 SET and MYND domain protein 4 K11426|1|9e-17|89.0|aga:AgaP_AGAP008954|SET and MYND domain-containing protein - GO:0046914//transition metal ion binding - 36598 2047.72 15.14 14.285 -0.0838641690493598 Down 0.162891295733721 Tfb1 TFB1 ortholog, isoform D K03141|1|0.0|1149|dme:Dmel_CG8151|transcription initiation factor TFIIH subunit H1 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0005488//binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled;GO:0005488//binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled;GO:0005488//binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled GO:0006289//nucleotide-excision repair;GO:0006354//DNA-dependent transcription, elongation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0006289//nucleotide-excision repair;GO:0006354//DNA-dependent transcription, elongation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation;GO:0006289//nucleotide-excision repair;GO:0006354//DNA-dependent transcription, elongation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation 35931 1078.60 154.905 157.33 0.022410080999401 Up 0.0916325452384097 alc alicorn, isoform B K07199|1|2e-156|552|dme:Dmel_CG8057|5'-AMP-activated protein kinase, regulatory beta subunit - - GO:0030011//maintenance of cell polarity;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis 44148 1279.00 0.61 1.115 0.870162562357418 Up 0.239499405626734 PpD5 protein phosphatase D5 K01090|1|0.0|711|dme:Dmel_CG10138|protein phosphatase [EC:3.1.3.16];K06269|2|1e-112|406|ame:409430|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 19835793 341.00 0.01 0.15 3.90689059560852 Up 0.171410645885616 3885619 1090.00 0.04 0.01 -2 Down 0.0694426099590543 CG34011 CG34011 - - - - 39753 1964.47 134.225 130.985 -0.0352517966827752 Down 0.134625544842161 th thread, isoform F K04725|1|0.0|863|dme:Dmel_CG12284|baculoviral IAP repeat-containing 2/3/4 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0008356//asymmetric cell division;GO:0016567//protein ubiquitination;GO:0006997//nucleus organization;GO:0043066//negative regulation of apoptotic process;GO:0010466//negative regulation of peptidase activity;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0008356//asymmetric cell division;GO:0016567//protein ubiquitination;GO:0006997//nucleus organization;GO:0043066//negative regulation of apoptotic process;GO:0010466//negative regulation of peptidase activity;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007297//ovarian follicle cell migration;GO:0009886//post-embryonic morphogenesis;GO:0008356//asymmetric cell division;GO:0016567//protein ubiquitination;GO:0006997//nucleus organization;GO:0043066//negative regulation of apoptotic process;GO:0010466//negative regulation of peptidase activity 37800 3595.86 363.915 407.885 0.164560934882754 Up 0.370558710870427 kcc kazachoc, isoform G K13627|1|0.0|1100|hsa:10723|solute carrier family 12 member 7 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015296;GO:0015296;GO:0015296;GO:0015296 GO:0015698//inorganic anion transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0030001//metal ion transport 41859 794.00 31.21 30.03 -0.0556038823620606 Down 0.154801215163122 mRpL9 mitochondrial ribosomal protein L9 - - - - 317974 4464.91 2.06 4.395 1.09321882796019 Up 0.495145951657641 CG33791 CG33791, isoform F K00164|1|0.0|2234|dme:Dmel_CG33791|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process;GO:0009060//aerobic respiration 39502 1641.00 1.8 1.5 -0.263034405833794 Down 0.142616563201691 Poc1 proteome of centrioles 1, isoform B K01062|1|1e-33|144|smm:Smp_129340|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - - - 39582 1363.49 0.575 2.265 1.97787718910186 Up 0.475729758288205 CG3919 CG3919, isoform C - - GO:0003676//nucleic acid binding - 3885644 1148.00 1.65 1.08 -0.611434712082347 Down 0.237782327301545 CG34002 CG34002 - - - - 34331 4861.00 0.245 0.73 1.57511471476481 Up 0.261623299432043 SoYb sister of Yb, isoform C K12835|1|7e-06|53.9|smm:Smp_131770|ATP-dependent RNA helicase DDX42 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled - 19835059 301.00 0.15 0.01 -3.90689059560852 Down 0.171410645885616 10178937 2306.00 1.54 1.625 0.0775093672209156 Up 0.0667679302602034 40490 1502.77 8.695 9.67 0.153329862170254 Up 0.22011623299432 CG14450 CG14450, isoform B - - - - 31522 1750.00 0.795 0.69 -0.204358498506186 Down 0.0854576674151367 CG4020 CG4020, isoform B K13356|1|5e-92|338|phu:Phum_PHUM288600|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 3355155 460.67 546.08 564.985 0.0491002458317177 Up 0.161504424778761 CG40002 CG40002, isoform B K03958|1|5e-54|210|dme:Dmel_CG40002|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 2 [EC:1.6.5.3 1.6.99.3] - - - 37298 5174.00 4.42 5.21 0.237237002887077 Up 0.229593184519878 CG16868 CG16868 - - - - 41860 1299.00 17.03 13.7 -0.313902541830654 Down 0.427420420023775 FK506-bp1 FK506-binding protein 1 K01802|1|1e-130|466|dme:Dmel_CG6226|peptidylprolyl isomerase [EC:5.2.1.8] - - - 37399 2278.26 128.74 79.57 -0.694163869852767 Down 0.682076343943997 CG9394 CG9394, isoform B - - - - 35015 1621.32 2.16 4.44 1.03952836418664 Up 0.488938053097345 CG13280 CG13280, isoform B K00078|1|1e-54|214|dre:449558|dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179] - GO:0003824//catalytic activity - 43332 2353.19 26.425 27.12 0.0374537068662987 Up 0.116034869898296 CG12428 CG12428, isoform E K05940|1|0.0|1271|dme:Dmel_CG12428|carnitine O-octanoyltransferase [EC:2.3.1.137] GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups - 43136 2373.71 35.555 38.68 0.121535338543193 Up 0.268062343151499 CG42235 CG42235, isoform E K03307|1|1e-153|543|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015373;GO:0015373;GO:0015373 GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport 43064 1442.00 90.985 118.445 0.380516674441084 Up 0.578622374851407 CG10553 CG10553 - - - - 19835705 751.00 0.11 0.065 -0.758991900496205 Down 0.0694426099590543 32562 1257.00 0.765 1.51 0.981016896632427 Up 0.297880068683133 Or13a odorant receptor 13a K08471|1|0.0|841|dme:Dmel_CG12697|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38725 4380.61 40.565 47.445 0.226020568174474 Up 0.421839915466913 CG10226 CG10226, isoform B K01509|1|0.0|1365|dpo:Dpse_GA10136|adenosinetriphosphatase [EC:3.6.1.3];K05658|2|0.0|1122|aga:AgaP_AGAP005639|ATP-binding cassette, subfamily B (MDR/TAP), member 1 GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 246511 1157.00 0.01 17.845 10.801304186049 Up 0.942808083476423 CG18853 CG18853 K01669|1|0.0|654|dme:Dmel_CG18853|deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] - GO:0003913//DNA photolyase activity GO:0006259//DNA metabolic process 31786 1132.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 Cp7Fc chorion protein c at 7F - - - - 42351 1724.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG6300 CG6300 K01904|1|6e-43|176|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 39251 735.00 568.81 504.73 -0.172434988883691 Down 0.387927618544446 Sod superoxide dismutase, isoform D K04565|1|2e-80|298|dsi:Dsim_GD12822|Cu/Zn superoxide dismutase [EC:1.15.1.1] GO:0044424//intracellular part GO:0003824//catalytic activity;GO:0016209//antioxidant activity;GO:0043169//cation binding GO:0006950//response to stress;GO:0010259//multicellular organismal aging;GO:0006800//oxygen and reactive oxygen species metabolic process 37729 1749.00 5.095 6.535 0.359105089629619 Up 0.33793422269185 Dcp-1 death caspase-1 K04489|1|0.0|666|dme:Dmel_CG5370|caspase invertebrate, apoptosis-related cysteine protease [EC:3.4.22.-] GO:0043234//protein complex GO:0004175//endopeptidase activity GO:0051605;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0003006//developmental process involved in reproduction;GO:0048102//autophagic cell death;GO:0030036//actin cytoskeleton organization;GO:0010212//response to ionizing radiation;GO:0006923//cleavage of cytoskeletal proteins involved in execution phase of apoptosis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007435//salivary gland morphogenesis 33307 1566.00 3.38 3.725 0.140217179067339 Up 0.133899088627658 Tgt tRNA-guanine transglycosylase K00773|1|0.0|869|dme:Dmel_CG4947|queuine tRNA-ribosyltransferase [EC:2.4.2.29] - GO:0016763//transferase activity, transferring pentosyl groups GO:0006400//tRNA modification 40149 2167.85 360.185 127.26 -1.50095907437475 Down 0.769911504424779 verm vermiform, isoform I K06233|1|3e-07|57.4|hsa:4036|low density lipoprotein-related protein 2 - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0030247//polysaccharide binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0030247//polysaccharide binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0030247//polysaccharide binding GO:0009887//organ morphogenesis;GO:0060560//developmental growth involved in morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0006022;GO:0007610//behavior;GO:0009887//organ morphogenesis;GO:0060560//developmental growth involved in morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0006022;GO:0007610//behavior;GO:0009887//organ morphogenesis;GO:0060560//developmental growth involved in morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0006022;GO:0007610//behavior 5740338 882.00 0.01 0.265 4.7279204545632 Up 0.2511557257958 CG34177 CG34177 - - - - 39684 2281.00 57.27 56.725 -0.0137948995653939 Down 0.0669660546823405 CG7739 CG7739 - - - GO:0006351//transcription, DNA-dependent;GO:0023060 36408 1927.87 43.36 44.35 0.0325693478345544 Up 0.106392814687624 Dgkepsilon diacyl glycerol kinase epsilon, isoform B K00901|1|0.0|1075|dme:Dmel_CG8657|diacylglycerol kinase [EC:2.7.1.107] - GO:0016301//kinase activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process 19835812 1215.00 0.92 1.185 0.365181292841246 Up 0.148064984810461 35182 1344.00 13.73 14.92 0.119915910108137 Up 0.21582353718135 CG17572 CG17572 K01312|1|1e-32|140|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|4e-28|125|dme:Dmel_CG4920| [EC:3.4.21.-];K09632|3|1e-27|124|hsa:1506|chymotrypsin-like protease [EC:3.4.21.-];K08664|4|3e-27|122|mmu:76560|protease, serine, 8 (prostasin) [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 34444 1555.00 4.485 4.925 0.135015739424477 Up 0.151565182934883 CG13144 CG13144 - GO:0044423 - - 44135 2225.66 3.86 4.205 0.123504952987064 Up 0.129969620921939 ect ectodermal, isoform F - - - - 33250 483.00 0.94 2.975 1.66215700651767 Up 0.498976357152292 CG13947 CG13947 - - - - 31353 6634.08 3.615 4.24 0.230068617612081 Up 0.201591599524501 CG43689 CG43689, isoform H K11307|1|9e-07|56.2|xla:779136|histone acetyltransferase MYST2 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent 42251 823.00 0.145 0.135 -0.103093492964104 Down 0.0433232069739797 CG7715 CG7715 - - GO:0030247//polysaccharide binding GO:0006022 250736 1989.74 40.68 30.7 -0.406081023599958 Down 0.557984414212125 bwa brain washing, isoform B K01441|1|1e-161|570|dme:Dmel_CG13969|alkaline ceramidase [EC:3.5.1.23] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0006672//ceramide metabolic process 35376 5632.51 54.505 63.675 0.224338473337772 Up 0.42388720116233 Nhe2 Na[+]/H[+] hydrogen exchanger 2, isoform L K12040|1|7e-158|558|bta:407112|solute carrier family 9, member 3 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity;GO:0005451//monovalent cation:hydrogen antiporter activity GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport;GO:0055067;GO:0030001//metal ion transport 41073 2136.00 7.775 7.88 0.0193529544384114 Up 0.0586448289525822 E(var)3-9 enhancer of variegation 3-9 K09228|1|2e-08|61.2|bta:100137841|KRAB domain-containing zinc finger protein;K09222|2|3e-08|60.8|tgu:100228357|RE1-silencing transcription factor;K10498|3|4e-08|60.5|gga:418400|zinc finger and BTB domain-containing protein 11 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 38599 855.00 19.195 22.2 0.209829116390519 Up 0.356260731739532 CHMP2B charged multivesicular body protein 2b K12192|1|1e-99|362|dse:Dsec_GM14695|charged multivesicular body protein 2B - - GO:0006810//transport 246528 575.00 64.875 79.855 0.299720109161222 Up 0.512878087438912 CG30285 CG30285 - - - - 31862 444.00 3.915 2.435 -0.685090535208699 Down 0.384097213049795 CG15369 CG15369, isoform B K01373|1|2e-18|90.5|dvi:Dvir_GJ11017|cathepsin F [EC:3.4.22.41] - GO:0004866//endopeptidase inhibitor activity - 34856 1158.00 6.91 10.5 0.603631712165226 Up 0.512019548276318 CG4691 CG4691 - - - - 33783 1181.37 24.89 27.105 0.12299277660472 Up 0.253070928543125 Oscillin oscillin, isoform H K02564|1|8e-158|556|dme:Dmel_CG6957|glucosamine-6-phosphate deaminase [EC:3.5.99.6] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0006041//glucosamine metabolic process;GO:0006041//glucosamine metabolic process 317999 1084.00 4.36 5.38 0.303278037779698 Up 0.276482631092326 CG32371 CG32371 K10436|1|3e-59|228|dme:Dmel_CG3265|microtubule-associated protein, RP/EB family GO:0005874//microtubule;GO:0005819//spindle GO:0015631//tubulin binding GO:0008344//adult locomotory behavior;GO:0007052//mitotic spindle organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development 32294 482.78 23.67 28.625 0.274215987137054 Up 0.435609562805442 Tim9a Tim9a, isoform B K10836|1|5e-49|192|dme:Dmel_CG1660|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 36893 672.00 88.305 50.17 -0.815670190269608 Down 0.697629111081759 CG6429 CG6429 - - - - 36784 2453.00 9.635 9.635 3.20342650381492e-16 Up 0.0382380134724607 Aats-cys Cysteinyl-tRNA synthetase K01883|1|0.0|1323|dme:Dmel_CG8431|cysteinyl-tRNA synthetase [EC:6.1.1.16] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 32400 7702.93 13.755 15.265 0.15027144989057 Up 0.257198520670981 NetB Netrin-B, isoform G K06843|1|1e-104|382|dre:30227|netrin 1 GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007431//salivary gland development;GO:0006928//cellular component movement;GO:0008039//synaptic target recognition;GO:0007411//axon guidance;GO:0006810//transport;GO:0007431//salivary gland development;GO:0006928//cellular component movement;GO:0008039//synaptic target recognition;GO:0007411//axon guidance;GO:0006810//transport;GO:0007431//salivary gland development;GO:0006928//cellular component movement;GO:0008039//synaptic target recognition;GO:0007411//axon guidance;GO:0006810//transport;GO:0007431//salivary gland development;GO:0006928//cellular component movement;GO:0008039//synaptic target recognition;GO:0007411//axon guidance;GO:0006810//transport 31279 1046.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG14424 CG14424 - - - - 246579 459.00 9.9 4.68 -1.08091999538357 Down 0.608572183331132 CG30380 CG30380 - - - - 318099 573.29 2.835 1.835 -0.627568672099016 Down 0.315579183727381 CG32582 CG32582, isoform C - - - - 40245 3379.92 0.07 0.09 0.362570079384709 Up 0.0544181746136574 Toll-9 Toll-9, isoform C K05398|1|2e-30|135|ssc:396607|toll-like receptor 1;K10169|2|3e-30|134|bta:407237|toll-like receptor 6;K05401|3|6e-30|133|spu:587154|toll-like recepto 3 GO:0031224//intrinsic to membrane GO:0004872//receptor activity;GO:0005488//binding GO:0006952//defense response;GO:0023060 31057 489.00 0.255 0.38 0.57550217147209 Up 0.106161669528464 CG14628 CG14628 - - - - 35595 4761.28 30.065 32.55 0.11457258485693 Up 0.246202615242372 CG15236 CG15236, isoform B - - - - 33742 1447.61 11.855 9.775 -0.278327055287293 Down 0.360091137234183 CG5828 CG5828, isoform B K09680|1|0.0|703|dme:Dmel_CG5828|type II pantothenate kinase [EC:2.7.1.33] - - - 5740183 945.00 0.19 0.095 -1 Down 0.107350416061286 CG34236 CG34236, isoform C K09534|1|2e-09|62.0|ame:409594|DnaJ homolog subfamily C member 14 - GO:0046914//transition metal ion binding - 2768691 257.65 7.85 68.66 3.12870529817827 Up 0.816041474045701 Dup99B ductus ejaculatorius peptide 99B, isoform B - - - GO:0007621//negative regulation of female receptivity;GO:0050795//regulation of behavior 34584 680.00 1.575 2.115 0.425305834732671 Up 0.218465196143178 CG12307 CG12307 - - - - 40062 1281.00 9.545 9.615 0.0105416599359595 Up 0.0513802668075551 CG6843 CG6843 K06066|1|2e-135|482|dme:Dmel_CG6843|CBF1 interacting corepressor - - - 42286 844.00 25.515 26.38 0.0480989228670036 Up 0.132776383568881 CG6013 CG6013 - - - - 3885617 1653.00 0.12 0.08 -0.584962500721156 Down 0.0687491744815744 ppk10 pickpocket 10 - GO:0016020//membrane GO:0015923//mannosidase activity;GO:0005261//cation channel activity GO:0030001//metal ion transport;GO:0044238//primary metabolic process 43645 1850.08 1 1.9 0.925999418556223 Up 0.324891031567825 CG1340 CG1340, isoform C K03258|1|4e-10|66.6|tad:TRIADDRAFT_53556|translation initiation factor eIF-4B - GO:0003676//nucleic acid binding - 43856 15533.89 8.175 9.625 0.235567810084181 Up 0.298738607845727 nej nejire, isoform E K04498|1|0.0|1936|dme:Dmel_CG15319|E1A/CREB-binding protein [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0004468//lysine N-acetyltransferase activity;GO:0046914//transition metal ion binding GO:0010468//regulation of gene expression;GO:0016570//histone modification;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0016570//histone modification;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0016570//histone modification;GO:0006351//transcription, DNA-dependent 36714 3857.00 0.335 0.365 0.123735368422245 Up 0.0528661999735834 CG12964 CG12964, isoform C - - - - 36171 9309.04 8.08 8.33 0.0439612026137528 Up 0.0868445383700964 shn schnurri, isoform F K09239|1|1e-39|167|dre:100000517|human immunodeficiency virus type I enhancer-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009888//tissue development;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0048565//digestive tract development;GO:0007399//nervous system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009888//tissue development;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0048565//digestive tract development;GO:0007399//nervous system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009888//tissue development;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0048565//digestive tract development;GO:0007399//nervous system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009888//tissue development;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0045704;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008306//associative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048592//eye morphogenesis;GO:0048565//digestive tract development;GO:0007399//nervous system development;GO:0007476//imaginal disc-derived wing morphogenesis 318636 777.00 30.655 35.155 0.197607489834733 Up 0.373926826046757 CG31229 CG31229 K10836|1|5e-102|370|dme:Dmel_CG31229|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic to membrane GO:0022892 GO:0006605//protein targeting 40680 1688.80 318.365 317.175 -0.0054026783680646 Down 0.0689803196407344 exba krasavietz, isoform G K03260|1|2e-09|64.3|dya:Dyak_GE12504|translation initiation factor eIF-4F GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424//intracellular part GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition;GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition;GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition;GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition;GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition;GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition;GO:0006412//translation;GO:0007613//memory;GO:0007292//female gamete generation;GO:0016198//axon choice point recognition 39545 565.00 0.08 0.165 1.04439411935845 Up 0.0978734645357284 CG17362 CG17362 - - - - 39197 904.16 1.505 2.595 0.785971051598179 Up 0.345330867784969 CG6527 CG6527, isoform B - - - - 40758 1516.00 0.235 0.245 0.0601209924375706 Up 0.0422335226522256 Osi4 osiris 4, isoform B - - - - 19835306 659.00 10.215 17.205 0.752138688003754 Up 0.608737287016246 42451 999.00 1290.855 583.05 -1.14663544024842 Down 0.750660414740457 CG4000 CG4000 - - - - 50457 492.00 12.645 17.57 0.474547154345137 Up 0.523510764760269 CG34168 CG34168 - - - - 318136 466.00 3.455 1.66 -1.05750246904133 Down 0.448718795403513 CG32641 CG32641 K09510|1|4e-16|83.2|tad:TRIADDRAFT_49929|DnaJ homolog subfamily B member 4;K09507|2|4e-15|79.7|xtr:493474|DnaJ homolog subfamily B member 1;K09515|4|7e-15|79.0|nve:NEMVE_v1g106836|DnaJ homolog subfamily B member 9 - GO:0005515//protein binding - 5740252 9847.63 36.065 35.7 -0.0146753495582642 Down 0.0651499141460837 Not1 Not1, isoform H K12604|1|0.0|4542|dme:Dmel_CG34407|CCR4-NOT transcription complex subunit 1 - - GO:0048513//organ development;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0048812//neuron projection morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0048513//organ development;GO:0048812//neuron projection morphogenesis 31289 846.00 21.39 0.875 -4.61150965533272 Down 0.845760137366266 CG3603 CG3603, isoform B K00044|1|4e-100|363|dpo:Dpse_GA17551|estradiol 17beta-dehydrogenase [EC:1.1.1.62];K13370|2|1e-58|226|mmu:14979|estradiol 17beta-dehydrogenase / testosterone 17beta-dehydrogenase / [EC:1.1.1.62 1.1.1.63] - - - 31006 1328.68 27.925 32.07 0.19966707307097 Up 0.369865275392947 mod(r) modifier of rudimentary, isoform F K12185|1|1e-107|390|dme:Dmel_CG17828|ESCRT-I complex subunit VPS37 - - - 37833 1639.00 66.605 77.735 0.222933831272959 Up 0.42956676793026 CG11388 CG11388 - GO:0031224//intrinsic to membrane GO:0005267//potassium channel activity;GO:0016740//transferase activity GO:0030001//metal ion transport 44260 1281.76 232.31 206.75 -0.168163928236583 Down 0.382512217672698 eIF-1A eukaryotic initiation factor 1A, isoform C K03236|1|4e-52|205|dvi:Dvir_GJ24550|translation initiation factor eIF-1A GO:0070993;GO:0070993 GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0006909//phagocytosis;GO:0007052//mitotic spindle organization;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation;GO:0006909//phagocytosis;GO:0007052//mitotic spindle organization;GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation 49636 3888.56 33.49 36.685 0.131459909115167 Up 0.283450006604147 hrg hiiragi, isoform D K00970|1|0.0|1215|dme:Dmel_CG9854|poly(A) polymerase [EC:2.7.7.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0070566//adenylyltransferase activity;GO:0003676//nucleic acid binding;GO:0070566//adenylyltransferase activity;GO:0003676//nucleic acid binding;GO:0070566//adenylyltransferase activity;GO:0003676//nucleic acid binding GO:0031124//mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing 32882 2580.00 8.955 8.97 0.00241455293330008 Up 0.0416061286487914 CG7326 CG7326, isoform B K12584|1|5e-13|76.6|tca:658490|scavenger mRNA-decapping enzyme DcpS [EC:3.-.-.-] - - - 37661 1652.97 224.79 247.135 0.136721486629633 Up 0.336448289525822 l(2)k09913 lethal (2) k09913, isoform I - - - - 33749 1617.00 119.865 76 -0.657339136603183 Down 0.675208030643244 Cyp28d1 Cyp28d1 K00517|1|0.0|985|dme:Dmel_CG10833| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 19834732 447.00 0.19 0.01 -4.24792751344359 Down 0.201558578787479 34952 2989.47 95.12 97.31 0.0328393551755961 Up 0.1121384229296 PRL-1 PRL-1, isoform D K01104|1|3e-97|356|dya:Dyak_GE19374|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 35805 605.00 0.865 1.71 0.983224287249173 Up 0.316206577730815 CG12126 CG12126 - - - - 14462574 495.00 0.25 0.47 0.910732661902913 Up 0.154338924844803 3885589 760.00 1.04 0.41 -1.34288771352301 Down 0.291672170122837 CG34021 CG34021 - - - - 41790 1999.00 0.485 0.505 0.0582986405646672 Up 0.0455355963545106 CG14856 CG14856 K08202|1|2e-39|164|tca:663415|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5;K08209|3|3e-37|157|mcc:696240|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13 - - - 42507 2505.00 3.46 3.075 -0.170185627410122 Down 0.147833839651301 Ice2 interacts with the C terminus of ELL 1, isoform C - - GO:0005488//binding;GO:0005488//binding - 32674 5496.00 20.675 24.165 0.225031665369088 Up 0.381389512613922 RSG7 regulator of G-protein signaling 7, isoform B K13765|1|1e-82|308|oaa:100078978|regulator of G-protein signaling 9 GO:0019897//extrinsic to plasma membrane;GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0008047//enzyme activator activity GO:0007166//cell surface receptor signaling pathway;GO:0006396//RNA processing 45577 1421.00 59.08 46.4 -0.348545020749855 Down 0.53985602958658 Faa fumarylacetoacetase K01555|1|0.0|863|dme:Dmel_CG14993|fumarylacetoacetase [EC:3.7.1.2] - GO:0016823 GO:0006520//cellular amino acid metabolic process 37381 2998.00 9.97 9.22 -0.112826753968858 Down 0.177156254127592 CG9346 CG9346 K12842|1|0.0|1474|dme:Dmel_CG9346|U2-associated protein SR140 - - - 33694 1222.00 0.795 0.77 -0.046096414589454 Down 0.0483423590014529 CG15625 CG15625 - - - - 42707 4052.00 31.91 39.465 0.306565140607733 Up 0.491480649848105 klg klingon K06774|1|1e-26|122|tgu:100226286|neurotrimin;K06773|3|2e-25|119|xtr:779942|opioid binding protein/cell adhesion molecule-like;K06775|4|2e-24|115|dre:445374|neuronal growth regulator 1 GO:0019898//extrinsic to membrane - GO:0007613//memory;GO:0001752//compound eye photoreceptor fate commitment;GO:0008306//associative learning 43655 4205.33 7.2 3.65 -0.980100442562295 Down 0.550323603222824 CG15544 CG15544, isoform B K11972|1|7e-09|63.9|bfo:BRAFLDRAFT_87257|E3 ubiquitin-protein ligase RNF19A [EC:6.3.2.19] - - - 4379906 275.00 6.31 2.16 -1.54660869281908 Down 0.606194690265487 31780 1729.00 5.785 6.65 0.201037381281062 Up 0.228536520935147 Es2 Es2 K13118|1|0.0|920|dme:Dmel_CG1474|protein DGCR14 GO:0005681//spliceosomal complex - GO:0000377;GO:0048731 36879 1378.00 0.445 0.68 0.611729410283942 Up 0.148659358076872 Arp53D Actin-related protein 53D K05692|1|0.0|731|dsi:Dsim_GD11215|actin beta/gamma 1 - - - 3772510 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 32238 2035.00 0.3 0.72 1.26303440583379 Up 0.232961299696209 CG4661 CG4661 - - GO:0005488//binding GO:0019941//modification-dependent protein catabolic process 37921 1956.96 72.395 88.96 0.297266727828907 Up 0.515453704926694 itp Ion transport peptide, isoform G - - GO:0005179//hormone activity;GO:0005179//hormone activity;GO:0005179//hormone activity;GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway 38211 1724.00 0.155 0.185 0.255257055242075 Up 0.0589420155857879 CG12011 CG12011 - - - - 12798394 903.29 2.74 4.02 0.553019608218402 Up 0.348632941487254 CG43397 CG43397, isoform B - - - - 41273 5495.39 41.885 38.06 -0.138158111904038 Down 0.302238805970149 hth homothorax, isoform I K09355|1|3e-09|65.1|bfo:BRAFLDRAFT_124474|pre-B-cell leukemia transcription factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007417//central nervous system development;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0010551;GO:0007380//specification of segmental identity, head;GO:0007431//salivary gland development;GO:0007472//wing disc morphogenesis;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007417//central nervous system development;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0010551;GO:0007380//specification of segmental identity, head;GO:0007431//salivary gland development;GO:0007472//wing disc morphogenesis;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007417//central nervous system development;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0010551;GO:0007380//specification of segmental identity, head;GO:0007431//salivary gland development;GO:0007472//wing disc morphogenesis;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007417//central nervous system development;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0010551;GO:0007380//specification of segmental identity, head;GO:0007431//salivary gland development;GO:0007472//wing disc morphogenesis;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007417//central nervous system development;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0010551;GO:0007380//specification of segmental identity, head;GO:0007431//salivary gland development;GO:0007472//wing disc morphogenesis 41756 2412.27 4.895 5.255 0.102381904358484 Up 0.12534671773874 HtrA2 HtrA2, isoform B K01362|1|0.0|791|dme:Dmel_CG8464| [EC:3.4.21.-];K08669|2|1e-83|310|mmu:64704|HtrA serine peptidase 2 [EC:3.4.21.108] - - - 261663 1082.00 1.32 1.315 -0.00547513006615124 Down 0.041044776119403 CG32335 CG32335 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity - 5740392 1705.00 0.115 0.01 -3.52356195605701 Down 0.142748646149782 CG34162 CG34162 K13754|1|8e-15|82.0|rno:498185|solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 - - - 246593 1258.00 0.04 0.28 2.8073549220576 Up 0.195912032756571 CG30401 CG30401, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0001654//eye development;GO:0010468//regulation of gene expression;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0007389//pattern specification process 50196 443.00 1.785 0.635 -1.49109557725693 Down 0.391592920353982 CG5011 CG5011, isoform B - - - - 317945 526.00 3.36 1.095 -1.61753036317759 Down 0.51621318187822 CG32266 CG32266 - - - - 32498 5200.34 17.96 14.355 -0.323234019533965 Down 0.441223088099326 sog short gastrulation, isoform E K04657|1|0.0|2084|dme:Dmel_CG9224|chordin GO:0031224//intrinsic to membrane GO:0005102//receptor binding GO:0035270//endocrine system development;GO:0009888//tissue development;GO:0008595//anterior/posterior axis specification, embryo;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0030509//BMP signaling pathway;GO:0007310//oocyte dorsal/ventral axis specification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway 36214 952.00 0.615 0.73 0.247310053540777 Up 0.0916325452384097 lambdaTry lambdaTry K01312|1|8e-160|562|dme:Dmel_CG12350|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 246497 371.70 21.79 16.395 -0.410410294722846 Down 0.514000792497689 HSPC300 HSPC300, isoform B K05752|1|1e-35|147|dya:Dyak_GE11496|chromosome 3 open reading frame 10 GO:0043232 GO:0005488//binding GO:0065008;GO:0048638//regulation of developmental growth;GO:0009653//anatomical structure morphogenesis 59235 538.00 14683.745 10138.545 -0.534369342166654 Down 0.65998547087571 Nplp3 Neuropeptide-like precursor 3 - - - GO:0007186//G-protein coupled receptor signaling pathway 32775 1904.10 48.99 35.325 -0.471797731061549 Down 0.595297847047946 GS glutathione synthetase, isoform K K01920|1|0.0|1023|der:Dere_GG19140|glutathione synthase [EC:6.3.2.3] - GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559;GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process;GO:0033554//cellular response to stress;GO:0006749//glutathione metabolic process 39917 2028.00 58.96 54.16 -0.122508785520073 Down 0.280147932901862 rogdi rogdi, isoform B - - - GO:0008306//associative learning;GO:0008306//associative learning 33650 1846.00 15.065 15.715 0.0609415992042878 Up 0.134394399683001 MFS18 major facilitator superfamily transporter 18 K12303|1|0.0|867|dme:Dmel_CG15438|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 9 - GO:0015114//phosphate ion transmembrane transporter activity;GO:0046914//transition metal ion binding GO:0006810//transport 31542 1275.00 21.7 33.97 0.646566175547359 Up 0.631158367454762 CG4660 CG4660 - - - - 41342 2003.00 12.53 11.765 -0.090885094097563 Down 0.165499933958526 CG6672 zinc transporter 86D K03295|1|5e-10|66.6|smm:Smp_069170|cation efflux system protein, CDF family - - - 19835283 317.00 1.02 0.88 -0.212993723334198 Down 0.0942742042002377 41489 2406.00 0.375 0.625 0.736965594166206 Up 0.158928807290979 CG3942 CG3942 - - - - 40163 1220.29 31.155 33.56 0.107278998874019 Up 0.244716682076344 Fibp fibp, isoform G - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0019838//growth factor binding;GO:0019838//growth factor binding;GO:0019838//growth factor binding - 37042 4578.00 0.24 0.57 1.24792751344359 Up 0.204101175538238 thr three rows, isoform C - - - - 36498 4401.82 2.255 2.395 0.0868982224807995 Up 0.0794148725399551 mars mars, isoform D - GO:0031981//nuclear lumen;GO:0005876//spindle microtubule;GO:0031981//nuclear lumen;GO:0005876//spindle microtubule - GO:0007026//negative regulation of microtubule depolymerization;GO:0000278//mitotic cell cycle;GO:0043623//cellular protein complex assembly;GO:0007154//cell communication;GO:0007026//negative regulation of microtubule depolymerization;GO:0000278//mitotic cell cycle;GO:0043623//cellular protein complex assembly;GO:0007154//cell communication 43404 7741.22 12.3 14.075 0.19447660674099 Up 0.297516840575882 spg sponge, isoform H K05727|1|0.0|3853|dme:Dmel_CG31048|dedicator of cytokinesis 3/4/5 - GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0030695//GTPase regulator activity;GO:0019899//enzyme binding;GO:0032561//guanyl ribonucleotide binding;GO:0030695//GTPase regulator activity - 31013 1550.00 8.39 8.59 0.0339873206986403 Up 0.0763109232598072 CG13367 CG13367 - - - - 32352 3011.79 111.385 103.57 -0.104948787149771 Down 0.25498613129045 CG32626 AMP deaminase, isoform L K01490|1|0.0|1381|dse:Dsec_GM17581|AMP deaminase [EC:3.5.4.6] - GO:0005488//binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0005488//binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0005488//binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0005488//binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0005488//binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0009112;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0009112;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0009112;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0009112;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0009112;GO:0009127//purine nucleoside monophosphate biosynthetic process 32136 8267.35 31.965 33.44 0.0650817535770233 Up 0.173061682736759 CG43154 rudhira, isoform F - - - - 4379892 706.00 34.11 28.85 -0.241623436080559 Down 0.416094307224937 CG34136 CG34136 - - - - 36039 1406.00 0.065 0.08 0.299560281858908 Up 0.053394531765949 eve even skipped K09320|1|1e-128|460|dme:Dmel_CG2328|homeobox even-skipped homolog protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007411//axon guidance;GO:0010004//gastrulation involving germ band extension;GO:0007365//periodic partitioning;GO:0006355//regulation of transcription, DNA-dependent;GO:0042685//cardioblast cell fate specification;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0035287//head segmentation 318105 611.00 0.2 0.225 0.169925001442312 Up 0.0510500594373266 CG32595 hog - - - - 14462753 566.00 22.225 11.435 -0.95872705330546 Down 0.66137234183067 251900 1560.00 10.545 9.485 -0.152839416382216 Down 0.227479857350416 GlcAT-I GlcAT-I K10158|1|9e-157|553|dme:Dmel_CG32775|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135] GO:0016020//membrane GO:0015020//glucuronosyltransferase activity GO:0006029//proteoglycan metabolic process 39881 1757.00 54.795 50.02 -0.131539196902205 Down 0.296129969620922 TSG101 tumor susceptibility gene 101 ortholog K12183|1|0.0|738|dme:Dmel_CG9712|ESCRT-I complex subunit TSG101 - GO:0005488//binding;GO:0016881//acid-amino acid ligase activity GO:0006810//transport;GO:0030011//maintenance of cell polarity;GO:0060255;GO:0010627//regulation of intracellular protein kinase cascade;GO:0045570//regulation of imaginal disc growth;GO:0006464//cellular protein modification process 36486 1011.06 0.81 0.565 -0.519671040469437 Down 0.149319772817329 IM10 immune induced molecule 10, isoform C - - - - 319028 497.00 7.94 8.73 0.136842646486482 Up 0.197728173292828 CG31922 CG31922 K13152|1|3e-72|270|dme:Dmel_CG31922|U11/U12 small nuclear ribonucleoprotein 20 kDa protein GO:0030529//ribonucleoprotein complex GO:0046914//transition metal ion binding - 43578 566.00 0.145 0.37 1.35147237050138 Up 0.165400871747457 CG15526 CG15526 - - - - 19834984 534.00 0.08 0.01 -3 Down 0.110718531237617 3772189 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33866 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 35173 2931.24 48.41 61.49 0.345046712619632 Up 0.541308942015586 Acn acinus, isoform C K12875|1|0.0|1027|dme:Dmel_CG10473|apoptotic chromatin condensation inducer in the nucleus GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0005488//binding;GO:0005488//binding GO:0006623//protein targeting to vacuole;GO:0000377;GO:0012501//programmed cell death;GO:0006623//protein targeting to vacuole;GO:0000377;GO:0012501//programmed cell death 36874 468.00 33.7 35.045 0.056460032863955 Up 0.158730682868842 Acp53Ea accessory gland protein 53Ea - - - - 33485 1307.00 0.235 0.2 -0.232660756790275 Down 0.0575221238938053 CG2983 CG2983 K00731|1|3e-65|249|dgr:Dgri_GH23406|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0044464//cell part GO:0048531//beta-1,3-galactosyltransferase activity GO:0016266//O-glycan processing;GO:0009653//anatomical structure morphogenesis;GO:0006664//glycolipid metabolic process 42055 2996.62 1.71 2.335 0.449426224823764 Up 0.236626601505746 CG18213 CG18213, isoform D K11426|1|5e-06|53.9|tad:TRIADDRAFT_53251|SET and MYND domain-containing protein - - - 45783 3369.18 12.965 15.61 0.267848331124614 Up 0.38171971998415 Aats-val Valyl-tRNA synthetase, isoform C K01873|1|0.0|1977|dme:Dmel_CG4062|valyl-tRNA synthetase [EC:6.1.1.9] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 35881 2369.89 724.78 763.545 0.0751700402892133 Up 0.225795799762251 Ggamma1 G protein gamma 1, isoform C - GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0044430//cytoskeletal part;GO:0043234//protein complex;GO:0019897//extrinsic to plasma membrane;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0019897//extrinsic to plasma membrane;GO:0044430//cytoskeletal part GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0065008;GO:0007635//chemosensory behavior;GO:0023060;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0009790//embryo development;GO:0065008;GO:0007635//chemosensory behavior;GO:0023060;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0009790//embryo development;GO:0065008;GO:0007635//chemosensory behavior;GO:0023060;GO:0008105//asymmetric protein localization;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0009790//embryo development 34467 418.00 3.93 3.95 0.00732334080585872 Up 0.0432901862369568 CG17107 CG17107, isoform C - - - - 5740549 350.00 5.56 8.225 0.564930795899096 Up 0.464271562541276 CG34446 CG34446 - - - - 42303 2465.43 22.62 15.99 -0.500428990509489 Down 0.559074098533879 CG31475 CG31475, isoform B - - GO:0046872//metal ion binding - 3772075 1023.00 0.07 0.025 -1.48542682717024 Down 0.0803064324395721 His1:CG33831 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 40837 3425.00 5.175 5.24 0.0180079491507628 Up 0.0542200501915203 CG1979 CG1979 - - - - 36855 604.00 1200.12 1284.535 0.0980675320698632 Up 0.267170783251882 RpLP2 ribosomal protein LP2 K02943|1|4e-28|124|dme:Dmel_CG4918|large subunit ribosomal protein LP2 - - - 317833 697.00 54.38 53.495 -0.0236720974620422 Down 0.0875379738475763 CG32038 ghiberti - GO:0044464//cell part - GO:0015031//protein transport 38490 1429.00 211.315 240.96 0.18939849584048 Up 0.411669528463875 Chd64 Chd64, isoform C K13710|1|4e-10|66.2|xla:444424|Rho guanine nucleotide exchange factor 7;K06084|2|4e-10|66.2|mmu:380928|F-box protein 20 - GO:0008092//cytoskeletal protein binding GO:0006936//muscle contraction 42662 1307.00 7.685 5.82 -0.401026106782487 Down 0.382545238409721 CG6937 CG6937 K13208|1|9e-06|51.6|bta:520376|ELAV like protein 2/3/4 - GO:0005488//binding - 43247 1091.00 0.92 10.13 3.46085650274413 Up 0.755877691190067 CG6295 CG6295 K01046|1|9e-113|406|dme:Dmel_CG17191|triacylglycerol lipase [EC:3.1.1.3];K01058|1|9e-113|406|dme:Dmel_CG17191|phospholipase A1 [EC:3.1.1.32];K01059|2|5e-38|158|dpo:Dpse_GA18274|lipoprotein lipase [EC:3.1.1.34] - GO:0004091//carboxylesterase activity GO:0044238//primary metabolic process 42097 710.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG5866 CG5866 K09047|1|2e-06|52.4|ecb:100054803|cAMP response element-binding protein 5 - - - 36993 5683.83 10.95 8.46 -0.372201301368586 Down 0.415962224276846 Dcr-2 Dicer-2, isoform B K11592|1|0.0|664|nvi:100118589|endoribonuclease Dicer [EC:3.1.26.-] - - - 42806 3030.34 19.46 18.63 -0.0628840358394738 Down 0.143243957205125 Hrd3 Hrd3, isoform B K14026|1|0.0|1301|dme:Dmel_CG10221|SEL1 protein - - - 31293 10150.00 5.465 4.325 -0.337521363147818 Down 0.300884955752212 N notch, isoform B K02599|1|0.0|5166|dme:Dmel_CG3936|Notch - - - 42366 4602.54 13.295 22.17 0.73772499300964 Up 0.627460044908202 Pk92B protein kinase at 92B, isoform C K04426|1|0.0|2405|dme:Dmel_CG4720|mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] - GO:0004709//MAP kinase kinase kinase activity;GO:0032559;GO:0004709//MAP kinase kinase kinase activity;GO:0032559 GO:0065008;GO:0006464//cellular protein modification process;GO:0008219//cell death;GO:0065008;GO:0006464//cellular protein modification process;GO:0008219//cell death 34137 1245.00 31.42 27.98 -0.167287218129443 Down 0.330768722757892 Ostgamma oligosaccharide transferase gamma subunit K12669|1|3e-176|617|dme:Dmel_CG7830|oligosaccharyltransferase complex subunit gamma - - - 40995 587.00 2.955 3.835 0.376068447325401 Up 0.272652225597675 CG18193 CG18193 K02270|1|3e-50|197|dme:Dmel_CG18193|cytochrome c oxidase subunit VIIa [EC:1.9.3.1] GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity - 38992 1364.00 7.585 17.87 1.23631854879446 Up 0.679170519085986 CG13305 CG13305, isoform C - - - - 246606 973.10 8.415 4.475 -0.91107558917833 Down 0.559965658433496 CG30424 CG30424, isoform E - - - - 37813 917.00 1.25 1.31 0.0676387168753633 Up 0.0583476423193766 CG13566 CG13566 - - - - 40740 1071.00 0.04 0.045 0.169925001442312 Up 0.0382380134724607 CG10280 CG10280, isoform B K08076|1|2e-37|156|cel:F09E8.6|astacin [EC:3.4.24.21];K08778|2|3e-36|152|ptr:741606|astacin-like metalloendopeptidase [EC:3.4.-.-] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 10178962 1349.46 9.135 13.145 0.525037507990557 Up 0.513571522916392 32873 4548.00 9.05 10.79 0.253705167517449 Up 0.323372077664773 CG7058 CG7058 K10481|1|4e-13|78.2|hmg:100203646|BTB/POZ domain-containing protein 9;K10523|2|1e-10|69.7|mdo:100021911|speckle-type POZ protein - GO:0005488//binding - 39357 909.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 CG11570 CG11570, isoform B K01873|1|2e-15|82.4|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding GO:0006022 35899 360.94 190.815 197.49 0.0496050172833927 Up 0.157938185180293 Tom7 translocase of outer membrane 7, isoform B - GO:0031966//mitochondrial membrane GO:0008320//protein transmembrane transporter activity GO:0006605//protein targeting 35280 535.00 4.495 5.055 0.169389976388567 Up 0.178708228767666 CG13965 CG13965 - - - - 2768730 279.00 733.84 493.055 -0.57371695747777 Down 0.670387003037908 CG12158 CG12158 - - - - 32511 1486.00 4.02 3.9 -0.0437213774293181 Down 0.0677255316338661 CG8191 CG8191 - - - - 317824 2006.93 73.245 84.965 0.214138389316436 Up 0.420552106723022 Zyx zyxin, isoform L K12792|1|4e-76|286|mdo:100018084|thyroid receptor-interacting protein 6 - - - 38825 1652.00 3.065 4.345 0.503469103123619 Up 0.34232598071589 CG8564 CG8564, isoform C K08780|1|2e-29|130|hsa:1359|carboxypeptidase A3 [EC:3.4.17.1] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 19835033 432.00 0.1 0.24 1.26303440583379 Up 0.128681812178048 319026 1980.80 4.83 5.32 0.139403056665416 Up 0.15975432571655 CG43755 CG43755, isoform D K05858|1|2e-21|104|dya:Dyak_GE16747|phospholipase C, beta [EC:3.1.4.11] - - - 44548 3381.50 134.24 142.48 0.0859448006617958 Up 0.236956808875974 lola longitudinals lacking, isoform Z K09237|1|1e-38|161|aga:AgaP_AGAP003537|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development;GO:0007626//locomotory behavior;GO:0001752//compound eye photoreceptor fate commitment;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-dependent;GO:0016198//axon choice point recognition;GO:0002118//aggressive behavior;GO:0006915//apoptotic process;GO:0042051//compound eye photoreceptor development 14462480 879.00 0.095 0.2 1.07400058144378 Up 0.11236956808876 14462778 411.00 0.72 0.35 -1.04064198449735 Down 0.212092193897768 CG43760 CG43760 - - - - 42077 651.00 5.09 4.71 -0.111938596462912 Down 0.132049927354379 Det deterin K08731|1|2e-87|321|dme:Dmel_CG12265|baculoviral IAP repeat-containing 5 - - - 48971 5045.32 1142.165 1310.405 0.198241685795469 Up 0.432241447629111 Atpalpha Na pump alpha subunit, isoform K K01539|1|0.0|1936|dsi:Dsim_GD19388|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0005887//integral to plasma membrane GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559;GO:0008556//potassium-transporting ATPase activity;GO:0032559 GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis;GO:0009605//response to external stimulus;GO:0007626//locomotory behavior;GO:0007267//cell-cell signaling;GO:0007043//cell-cell junction assembly;GO:0010259//multicellular organismal aging;GO:0035151//regulation of tube size, open tracheal system;GO:0006812//cation transport;GO:0009792//embryo development ending in birth or egg hatching;GO:0009628//response to abiotic stimulus;GO:0050877//neurological system process;GO:0009206;GO:0007416//synapse assembly;GO:0048871//multicellular organismal homeostasis 14462512 428.00 0.395 0.115 -1.78021879212009 Down 0.197067758552371 CG43694 CG43694 - - - - 12798024 541.00 0.38 0.59 0.634715535918256 Up 0.139776779817726 CG43233 CG43233, isoform B - - - - 32440 602.00 15.77 15.57 -0.0184137157114732 Down 0.0696077136441685 CG15027 CG15027 - - - - 59217 1938.89 0.48 1.06 1.14295795384204 Up 0.271232333905693 CG18869 CG18869, isoform B K00699|1|2e-25|117|dpo:Dpse_GA19741|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 326148 2641.37 80.295 69.645 -0.205290371748332 Down 0.418306696605468 CG31523 CG31523, isoform G K03254|1|4e-74|236|dse:Dsec_GM10701|translation initiation factor eIF-3 subunit 10;K10250|3|7e-71|269|rno:361895|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process 41282 875.49 5.265 5.86 0.154467133396531 Up 0.176991150442478 CG31278 CG31278, isoform B K01462|1|2e-138|491|dme:Dmel_CG31278| [EC:3.5.1.88] - GO:0046914//transition metal ion binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0010467//gene expression 43357 901.12 8.78 8.02 -0.130618703080438 Down 0.190331528199709 CG4884 CG4884, isoform B - - GO:0003676//nucleic acid binding - 37204 1270.00 6.065 5.855 -0.0508384746192949 Down 0.0851935015189539 CG7137 CG7137 - - - - 39955 2058.00 5.295 7.68 0.53647562672882 Up 0.443666622639017 U4-U6-60K U4-U6 small nuclear riboprotein factor 60K K12662|1|0.0|901|dme:Dmel_CG6322|U4/U6 small nuclear ribonucleoprotein PRP4 - - - 42233 1293.16 2.04 3.115 0.610663011052506 Up 0.327004358737287 CG14305 CG14305, isoform D K08811|1|4e-175|613|dme:Dmel_CG14305|testis-specific serine kinase [EC:2.7.11.1] - GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0048869//cellular developmental process;GO:0006464//cellular protein modification process;GO:0048869//cellular developmental process 41573 1710.00 0.095 0.26 1.45251220469751 Up 0.140602298243297 CG5724 CG5724 K00699|1|0.0|746|dme:Dmel_CG5999|glucuronosyltransferase [EC:2.4.1.17] - - - 33078 1114.42 58.33 60.94 0.0631514258727207 Up 0.170948355567296 Ntf-2 nuclear transport factor-2, isoform E - GO:0044464//cell part;GO:0044464//cell part GO:0008565//protein transporter activity;GO:0008565//protein transporter activity GO:0002777;GO:0006605//protein targeting;GO:0002777;GO:0006605//protein targeting 41210 990.00 0.12 0.09 -0.415037499278844 Down 0.0616827367586845 CG8534 CG8534 K00680|1|2e-151|535|dme:Dmel_CG8534| [EC:2.3.1.-];K10250|5|7e-39|160|mdo:100032201|elongation of very long chain fatty acids protein 7 GO:0031224//intrinsic to membrane GO:0004312//fatty acid synthase activity GO:0019748//secondary metabolic process;GO:0007617//mating behavior 38090 1338.18 5.82 9.595 0.721263653287096 Up 0.534902919033153 CG13897 hinge3, isoform B - - GO:0003676//nucleic acid binding - 44964 1856.00 0.39 0.655 0.748020782675202 Up 0.162627129837538 Actn3 alpha actinin 3 K05699|1|3e-08|60.5|smm:Smp_034550|actinin alpha - GO:0003779//actin binding GO:0007015//actin filament organization 31456 6827.14 32.515 49.765 0.614026019745317 Up 0.640833443402457 SK small conductance calcium-activated potassium channel, isoform U K01047|1|0.0|1044|dme:Dmel_CG10706|phospholipase A2 [EC:3.1.1.4];K04943|2|3e-171|603|mdo:100016183|potassium intermediate/small conductance calcium-activated channel subfamily N member 2;K04944|5|4e-169|596|hsa:3782|potassium intermediate/small conductance calcium-activated channel subfamily N member 3 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport 42809 2222.60 27.74 24.725 -0.16599726667713 Down 0.323900409457139 CG10217 CG10217, isoform B K12386|1|1e-12|75.1|nvi:100114326|cystinosin - - - 35890 2410.00 15.745 16.315 0.0513052299564543 Up 0.120426627922335 CG8243 CG8243 K12486|1|0.0|884|dme:Dmel_CG8243|stromal membrane-associated protein - GO:0005083//small GTPase regulator activity;GO:0046914//transition metal ion binding GO:0032012//regulation of ARF protein signal transduction 38346 2675.00 8.2 6.76 -0.278600663223262 Down 0.314489499405627 pgant6 polypeptide GalNAc transferase 6, isoform C K00710|1|0.0|1204|dme:Dmel_CG2103|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process;GO:0009311//oligosaccharide metabolic process 43303 2842.00 0.91 0.035 -4.70043971814109 Down 0.433793422269185 CG13978 CG13978 K05285|1|1e-121|437|dvi:Dvir_GJ20398|phosphatidylinositol glycan, class N [EC:2.7.-.-] GO:0031090//organelle membrane GO:0003824//catalytic activity GO:0006497//protein lipidation 40796 2580.00 34.615 19.74 -0.810275358360317 Down 0.664839519218069 Neurochondrin neurochondrin - - - - 14462663 684.00 0.07 0.01 -2.8073549220576 Down 0.100680227182671 50149 3657.00 23.085 25.335 0.134176096473176 Up 0.266510368511425 CG30158 CG30158 K07841|1|4e-25|117|xtr:100135197|DIRAS family, GTP-binding Ras-like 2;K07844|2|2e-24|115|tgu:100229182|RASD family, member 2;K07840|5|5e-24|114|xtr:780240|DIRAS family, GTP-binding Ras-like 1 GO:0044464//cell part GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction 19835015 897.00 0.175 0.255 0.543142325026529 Up 0.0890899484876502 35162 1546.27 2.525 3.435 0.444026711178943 Up 0.284704794611016 CG10650 CG10650, isoform B K05637|1|8e-06|52.0|dre:569971|laminin, alpha 1 - - - 34793 1705.44 51.935 57.045 0.135393313282678 Up 0.31151763307357 Arpc1 Actin-related protein 2/3 complex, subunit 1, isoform B K05757|1|0.0|779|dme:Dmel_CG8978|actin related protein 2/3 complex, subunit 1A/1B GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0048592//eye morphogenesis;GO:0008064//regulation of actin polymerization or depolymerization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007409//axonogenesis;GO:0007300//ovarian nurse cell to oocyte transport;GO:0048592//eye morphogenesis;GO:0008064//regulation of actin polymerization or depolymerization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007409//axonogenesis;GO:0007300//ovarian nurse cell to oocyte transport 31760 2064.41 96.5 120.62 0.321868292817222 Up 0.539459780742306 Trxr-1 thioredoxin reductase-1, isoform C K00384|1|0.0|944|dme:Dmel_CG2151|thioredoxin reductase (NADPH) [EC:1.8.1.9] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0042802//identical protein binding;GO:0030554//adenyl nucleotide binding;GO:0016209//antioxidant activity;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0042802//identical protein binding;GO:0030554//adenyl nucleotide binding;GO:0016209//antioxidant activity;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0042802//identical protein binding;GO:0030554//adenyl nucleotide binding;GO:0016209//antioxidant activity;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H GO:0010259//multicellular organismal aging;GO:0033554//cellular response to stress;GO:0008152//metabolic process;GO:0019725//cellular homeostasis;GO:0010259//multicellular organismal aging;GO:0033554//cellular response to stress;GO:0008152//metabolic process;GO:0019725//cellular homeostasis;GO:0010259//multicellular organismal aging;GO:0033554//cellular response to stress;GO:0008152//metabolic process;GO:0019725//cellular homeostasis 36314 467.00 9.15 6.16 -0.570841392476503 Down 0.482499009377889 SmF small ribonucleoprotein particle protein SmF K11098|1|1e-38|157|dvi:Dvir_GJ21558|small nuclear ribonucleoprotein F GO:0032991//macromolecular complex GO:0005488//binding - 37439 2947.00 0.835 0.96 0.201258208247104 Up 0.0884955752212389 CG15666 CG15666 - - - - 42590 1194.46 121.85 125.905 0.0472293261336429 Up 0.155428609166557 Cchl cytochrome c heme lyase, isoform B K01764|1|1e-160|566|dme:Dmel_CG6022|cytochrome c heme-lyase [EC:4.4.1.17] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0016846//carbon-sulfur lyase activity GO:0017003 19836247 651.00 0.185 0.29 0.648527629498622 Up 0.098632941487254 246568 1596.62 2.56 3.965 0.631177055703978 Up 0.370096420552107 spaw spacewatch, isoform B - - - - 19835808 680.00 0.12 0.07 -0.777607578663552 Down 0.0762779025227843 41442 2065.00 0.055 0.025 -1.13750352374993 Down 0.0654471007792894 CG14731 CG14731 - - - - 39147 4879.13 105.24 118.095 0.166264730442024 Up 0.374091929731872 CG8177 CG8177, isoform M K13855|1|3e-39|162|rno:24780|solute carrier family 4 (anion exchanger), member 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport 31023 2287.90 4.645 3.915 -0.246666289091612 Down 0.22265882974508 fz3 frizzled 3, isoform C K02645|1|3e-55|216|cfa:489809|frizzled 9;K02842|4|6e-54|212|xtr:448162|frizzled 10 - - - 35573 2281.00 5.97 4.025 -0.568742148262826 Down 0.417448157442874 Tdc1 tyrosine decarboxylase 1 K01593|1|1e-155|550|cel:K01C8.3|aromatic-L-amino-acid decarboxylase [EC:4.1.1.28];K01590|5|3e-137|489|dwi:Dwil_GK17782|histidine decarboxylase [EC:4.1.1.22] - GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0043436 19836143 839.00 0.385 0.395 0.0369942074822016 Up 0.0418702945449742 37443 1100.00 10.895 11.625 0.0935645197668494 Up 0.162594109100515 CG10795 CG10795 - - - - 43495 2350.00 1.66 2.05 0.304440668158521 Up 0.172236164311187 dmrt99B doublesex-Mab related 99B - - GO:0001071//nucleic acid binding transcription factor activity - 31767 10506.00 3.985 4.49 0.172135720750675 Up 0.170552106723022 nAcRalpha-7E nicotinic acetylcholine receptor alpha3, isoform C K05312|1|0.0|1053|dme:Dmel_CG2302|nicotinic acetylcholine receptor, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 40554 2006.00 23.31 24.065 0.0459874188360059 Up 0.128945978074231 tub tube - GO:0044424//intracellular part GO:0005515//protein binding GO:0000578//embryonic axis specification;GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress;GO:0051707//response to other organism;GO:0023060;GO:0048534 39127 2704.00 4.24 6.905 0.703577149694852 Up 0.481442345793158 CG33696 CG33696 K04282|1|2e-16|88.2|xla:373631|thyrotropin-releasing hormone receptor;K04323|4|1e-13|79.3|gga:428071|cysteinyl leukotriene receptor 2;K04322|5|1e-13|79.0|dre:553675|cysteinyl leukotriene receptor 1 GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060 37648 1562.00 4.82 5.24 0.120533665307489 Up 0.141890106987188 CG3831 CG3831, isoform C - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42272 1734.00 9.865 9.99 0.0181656270688595 Up 0.0611544049663188 Smu1 SMU1 ortholog, isoform C K13111|1|0.0|1013|dse:Dsec_GM13648|WD40 repeat-containing protein SMU1 GO:0005681//spliceosomal complex - - 12798408 1016.00 12.425 10.94 -0.183633113657092 Down 0.275095760137366 CG43191 CG43191 - - - - 47900 2362.00 9.88 9.455 -0.063433583634916 Down 0.116001849161273 Taf5 TBP-associated factor 5 K03130|1|0.0|1186|dme:Dmel_CG7704|transcription initiation factor TFIID subunit D4 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex GO:0003702//RNA polymerase II transcription factor activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-dependent transcription, initiation 37733 3164.00 16.85 15.87 -0.0864464632340388 Down 0.178146876238278 Pi3K59F phosphotidylinositol 3 kinase 59F K00914|1|0.0|1774|dme:Dmel_CG5373|phosphatidylinositol 3-kinase [EC:2.7.1.137] GO:0005942//phosphatidylinositol 3-kinase complex GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0000166//nucleotide binding;GO:0035004//phosphatidylinositol 3-kinase activity GO:0016192//vesicle-mediated transport;GO:0050658//RNA transport;GO:0031669//cellular response to nutrient levels;GO:0019932//second-messenger-mediated signaling;GO:0030384;GO:0007033//vacuole organization;GO:0006914//autophagy 14462890 2827.00 13.97 15.525 0.152261247698381 Up 0.259047681944261 19836236 853.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 38691 1401.00 1.8 4.345 1.27135927048473 Up 0.518821820103025 CG6602 CG6602 - - - - 37510 1583.00 0.285 0.695 1.28605105855877 Up 0.231805573900409 CG13501 CG13501, isoform B - - GO:0017111//nucleoside-triphosphatase activity - 42909 714.00 0.06 0.065 0.115477217419936 Up 0.0441487253995509 CG17784 CG17784 - - - - 33377 3823.73 37.675 38.885 0.0456062269615099 Up 0.140998547087571 CG4238 CG4238, isoform J K10591|1|8e-54|213|aga:AgaP_AGAP003133|E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19];K13305|2|4e-51|204|cfa:476189|E3 ubiquitin-protein ligase NEDD4-like [EC:6.3.2.19] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification;GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 33627 16852.00 1.595 1.05 -0.603167096098747 Down 0.232664113063004 ft fat K06813|1|0.0|974|dre:407978|cadherin 23 GO:0016021//integral to membrane GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding GO:0048859//formation of anatomical boundary;GO:0016055//Wnt receptor signaling pathway;GO:0045570//regulation of imaginal disc growth;GO:0000902//cell morphogenesis;GO:0008283//cell proliferation;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0035151//regulation of tube size, open tracheal system;GO:0006464//cellular protein modification process;GO:0030859//polarized epithelial cell differentiation;GO:0007472//wing disc morphogenesis;GO:0035556//intracellular signal transduction;GO:0048104//establishment of body hair or bristle planar orientation 39266 3674.00 14.08 14.005 -0.00770535056279095 Down 0.0526350548144235 Ube3a ubiquitin protein ligase E3A K10587|1|0.0|1672|dme:Dmel_CG6190|ubiquitin-protein ligase E3 A [EC:6.3.2.19] GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification 40515 6294.71 25.315 31.14 0.298776460169226 Up 0.469092590146612 nrm neuromusculin, isoform I K12567|1|2e-26|122|mmu:22138|titin [EC:2.7.11.1] GO:0016020//membrane;GO:0016020//membrane - GO:0009987//cellular process;GO:0009987//cellular process 39122 11046.15 19.425 24.14 0.313511077459949 Up 0.458823140932506 fry furry, isoform J - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0005488//binding GO:0007476//imaginal disc-derived wing morphogenesis;GO:0033674//positive regulation of kinase activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010975//regulation of neuron projection development;GO:0007166//cell surface receptor signaling pathway;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0033674//positive regulation of kinase activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010975//regulation of neuron projection development;GO:0007166//cell surface receptor signaling pathway 3772670 3509.97 37.935 39.56 0.0605128883747161 Up 0.162627129837538 bbx bobby sox, isoform E K03596|1|0.0|664|nve:NEMVE_v1g106275|GTP-binding protein LepA;K03234|2|5e-26|121|dme:Dmel_CG33158|elongation factor EF-2 [EC:3.6.5.3] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 3355120 690.71 73.95 62.715 -0.237739603221136 Down 0.448949940562673 CG40439 CG40439, isoform B - - - - 38582 4183.00 0.23 0.475 1.04629365227393 Up 0.166622639017303 CG13708 CG13708, isoform B - - - - 38956 1856.07 3.28 4.095 0.320167637022925 Up 0.253401135913354 CG13667 CG13667, isoform B K00327|1|6e-63|242|gga:417520|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] - GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process;GO:0008152//metabolic process 43089 514.00 2.38 3.765 0.661688291363985 Up 0.370228503500198 CG5079 CG5079 - - - - 19835636 388.00 9.56 9.99 0.06347405981167 Up 0.11689340906089 19835504 3359.00 0.035 0.15 2.09953567355091 Up 0.1267335886937 - CG45065 - - - - 31442 835.00 42.24 45.355 0.102651769587264 Up 0.238838990886277 snf sans fille K11094|1|6e-67|253|bta:767873|U2 small nuclear ribonucleoprotein B'' GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0017069//snRNA binding GO:0007542;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007292//female gamete generation 41364 716.00 20.455 18.985 -0.107593538268957 Down 0.220017170783252 mRpL40 mitochondrial ribosomal protein L40 - GO:0000315//organellar large ribosomal subunit - GO:0010467//gene expression 43053 1510.00 7.72 9.46 0.293239336071314 Up 0.342061814819707 CG11892 CG11892, isoform B - - - - 3772001 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 32794 1165.71 655.365 441.12 -0.571127454837477 Down 0.670188878615771 wupA wings up A, isoform M K12044|1|4e-09|62.8|xla:397803|troponin I, cardiac muscle;K12043|3|2e-07|57.0|xtr:496523|troponin I, fast skeletal muscle GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0031032//actomyosin structure organization;GO:0010927;GO:0048285;GO:0048513//organ development;GO:0014706//striated muscle tissue development 36372 1870.05 2.325 1.4 -0.731803889050427 Down 0.314951789723947 vis vismay, isoform B K11649|1|4e-12|73.6|tgu:100229325|SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C;K09355|2|1e-06|55.5|cbr:CBG16494|pre-B-cell leukemia transcription factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010468//regulation of gene expression;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process 31695 1521.04 56.72 63.41 0.160852844266061 Up 0.344769515255581 CG10932 CG10932, isoform B K00626|1|0.0|766|dme:Dmel_CG10932|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] - - - 40850 5562.96 15.765 16.445 0.0609238381520678 Up 0.136111478008189 Alh alhambra, isoform P K11348|1|1e-38|162|dre:393991|bromodomain and PHD finger-containing protein 1;K11349|4|3e-38|161|xtr:733743|bromodomain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development;GO:0035216;GO:0018988;GO:0002164//larval development 19835297 232.00 0.675 0.01 -6.07681559705083 Down 0.416688680491349 19835908 2616.00 0.29 0.07 -2.05062607306997 Down 0.175769383172632 19835066 893.10 1.21 1.595 0.398549376490275 Up 0.179863954563466 326129 1138.00 1.05 2.07 0.979241439833202 Up 0.345264826310923 CG31244 CG31244 - - - - 40962 3727.77 3.435 3.18 -0.111283333533745 Down 0.107086250165104 grn grain, isoform C K09182|1|8e-114|412|dya:Dyak_GE24873|GATA-binding protein 1/2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0009653//anatomical structure morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0009653//anatomical structure morphogenesis 31704 5250.00 13.795 16.845 0.288174971768484 Up 0.408268392550522 snz snazarus, isoform B - - - - 31735 1972.00 8.055 7.575 -0.0886387003462554 Down 0.137960639281469 CG2116 CG2116 K09228|1|3e-24|114|ptr:463955|KRAB domain-containing zinc finger protein - - - 35358 1227.53 16.795 17.45 0.0551952408625161 Up 0.134823669264298 CG14401 CG14401, isoform C - - - - 31881 1888.00 7.045 6.135 -0.199536362646732 Down 0.233621714436666 CG16892 CG16892, isoform B K04508|1|1e-06|54.7|tgu:100221758|transducin (beta)-like 1 - GO:0046914//transition metal ion binding - 38689 2362.00 12.805 7.14 -0.842711273568369 Down 0.595760137366266 CG42269 CG42269 K08202|1|2e-65|250|spu:578342|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 36494 1654.00 10.03 9.095 -0.141176062960694 Down 0.211365737683265 cbc crowded by cid - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0032559 GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation 19835668 582.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 32925 2373.79 10.745 8.125 -0.403225764624604 Down 0.430227182670717 CG8051 CG8051, isoform B K08189|1|4e-19|97.1|mcc:713985|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13 - - GO:0006810//transport 41932 4029.30 1.96 1.87 -0.0678153842275714 Down 0.0656122044644036 CG31291 CG45105, isoform I K10352|1|2e-12|75.1|oaa:100081497|myosin heavy chain;K11498|4|3e-11|71.2|aga:AgaP_AGAP006472|centromeric protein E - - - 36510 1633.28 0.46 0.57 0.309328058107729 Up 0.0941421212521464 CG13334 CG13334, isoform B K00016|1|0.0|711|dme:Dmel_CG13334|L-lactate dehydrogenase [EC:1.1.1.27] - GO:0016614//oxidoreductase activity, acting on CH-OH group of donors GO:0006007//glucose catabolic process 32424 2524.00 0.11 0.14 0.347923303420307 Up 0.0607911768590675 CG9503 CG9503 K00108|1|0.0|756|dme:Dmel_CG9518|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 3772665 1023.00 0.07 0.025 -1.48542682717024 Down 0.0803064324395721 His1:CG33822 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 33421 1123.54 140.13 110.695 -0.340175792701715 Down 0.5572249372606 CG3609 CG3609, isoform C K00078|1|7e-78|290|xtr:448579|dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 37831 2284.00 0.395 0.82 1.05377125644098 Up 0.22926297714965 CG3121 CG3121 - - GO:0015631//tubulin binding GO:0009987//cellular process 19835005 2508.00 7.75 6.72 -0.20573507738284 Down 0.249141460837406 14462808 1099.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 36436 6020.00 6.67 7.3 0.130209702582795 Up 0.17527407211729 Drl-2 derailed 2, isoform C K08252|1|0.0|1159|dme:Dmel_CG3915|receptor protein-tyrosine kinase [EC:2.7.10.1];K05128|2|4e-70|267|ame:410190|RYK receptor-like tyrosine kinase [EC:2.7.10.1] GO:0016021//integral to membrane GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0032559 GO:0006811//ion transport;GO:0007431//salivary gland development;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process 33892 2154.00 34.05 20.9 -0.704151855931188 Down 0.642550521727645 CG9507 CG9507 K01389|1|4e-32|140|dme:Dmel_CG3775|neprilysin [EC:3.4.24.11];K08635|2|4e-31|136|ame:408973|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 14462491 530.60 1.26 1.98 0.652076696579693 Up 0.271001188746533 5740491 1134.00 265.605 253.01 -0.0700878982858219 Down 0.201756703209616 38891 1703.11 6.245 7.765 0.314284352779344 Up 0.331825386342623 bip1 bip1, isoform B - - GO:0005488//binding - 37271 551.01 52.91 71.565 0.435713769298122 Up 0.595727116629243 Obp56h Odorant-binding protein 56h, isoform B - - GO:0005488//binding GO:0007606//sensory perception of chemical stimulus;GO:0051234//establishment of localization;GO:0010033//response to organic substance;GO:0007635//chemosensory behavior 31342 1792.00 159.58 167.155 0.0669066586301148 Up 0.198157442874125 VhaAC39-1 vacuolar H[+] ATPase AC39 subunit 1 K02146|1|0.0|716|dse:Dsec_GM12314|V-type H+-transporting ATPase subunit AC39 [EC:3.6.3.14] GO:0033176 GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 2768932 1599.00 0.45 0.765 0.765534746362977 Up 0.183760401532162 CG33322 CG33322 - GO:0044464//cell part - GO:0023060 33714 1986.00 16.8 17.67 0.0728408068854943 Up 0.153711530841368 CG14043 CG14043 - - - - 19835278 521.00 0.895 0.895 0 - 0.0382380134724607 31962 1872.94 15.83 16 0.0154106496375437 Up 0.0666688680491349 CG43740 CG43740, isoform C - - - - 32039 8171.00 12.305 11.755 -0.0659701188051385 Down 0.133469819046361 sev sevenless K05088|1|0.0|4659|dme:Dmel_CG18085|proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1] GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0004713//protein tyrosine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0007167//enzyme linked receptor protein signaling pathway 41981 3276.00 3.015 3.16 0.0677665562770183 Up 0.0780610223220182 pad poils au dos K09228|1|2e-23|112|hsa:90333|KRAB domain-containing zinc finger protein - - - 31997 8640.79 14.96 20.48 0.453105540112363 Up 0.529982829216748 X11Lbeta X11Lbeta, isoform E K04531|1|2e-130|468|dre:100003938|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) - GO:0005488//binding - 38674 1674.96 12.94 12.86 -0.00894697466456035 Down 0.0526350548144235 CG10479 CG10479, isoform B - - GO:0005488//binding - 14462865 1641.00 0.22 0.21 -0.0671141958585371 Down 0.042365605600317 246459 642.00 1.97 2.26 0.198127142958811 Up 0.132446176198653 CG30105 CG30105 K10745|1|7e-87|319|dme:Dmel_CG30105|ribonuclease H2 subunit C - - - 7354435 759.00 0.37 0.18 -1.03952836418664 Down 0.14816404702153 CG42302 CG42302 K10836|1|2e-11|67.0|dme:Dmel_CG11611|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane 3772388 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 39521 1933.69 15.74 12.78 -0.300547704560492 Down 0.410943072249373 CG10741 Tondu-domain-containing growth inhibitor, isoform B - - - - 38452 1506.93 182.81 195.335 0.0956054832729501 Up 0.260302469951129 Fie fire exit, isoform B - - - - 43702 1788.00 0.03 0.03 0 - 0.0382380134724607 CG15555 pickpocket 24 K04832|1|6e-16|85.9|dpo:Dpse_GA17142|amiloride-sensitive cation channel 5, intestinal GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 33233 2310.00 3.975 4.905 0.303298276047521 Up 0.264892352397306 CG2794 CG2794 K00856|1|8e-06|52.8|dvi:Dvir_GJ21287|adenosine kinase [EC:2.7.1.20] - GO:0016787//hydrolase activity - 117479 2086.42 0.405 0.85 1.06954093325308 Up 0.23517368907674 Gr64c gustatory receptor 64c, isoform B K08471|1|0.0|831|dme:Dmel_CG32256|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity - 36965 3102.00 3.96 3.44 -0.203091865377512 Down 0.178675208030643 Tes testin ortholog K04511|1|9e-46|186|spu:755492|prickle - - - 37415 1659.41 350.335 286.39 -0.290754008597222 Down 0.524138158763704 Pu punch, isoform C K01495|1|2e-142|506|dpo:Dpse_GA25103|GTP cyclohydrolase I [EC:3.5.4.16] - - - 39871 2209.00 3.325 2.985 -0.155623409123747 Down 0.138059701492537 Dbp73D dead box protein 73D K01529|1|2e-80|300|gga:416936| [EC:3.6.1.-] - GO:0032559;GO:0042623//ATPase activity, coupled - 39923 1138.00 0.44 0.945 1.10281080558378 Up 0.252377493065645 CG7707 CG7707 - - - - 35303 1011.00 0.5 0.515 0.0426443374084937 Up 0.0449742438251222 CG10651 CG10651, isoform B - - - - 33187 1660.00 1.625 1.52 -0.0963683944722314 Down 0.071721040813631 CG13693 CG13693 - - - - 31412 528.00 0.16 0.265 0.727920454563199 Up 0.104444591203276 CG15471 CG15471, isoform C - - - GO:0009056//catabolic process;GO:0009056//catabolic process 42182 1999.00 8.655 6.975 -0.311340602650089 Down 0.345396909259015 CG7175 mTerf5 - - - - 19834923 409.00 0.01 0.235 4.55458885167764 Up 0.229362039360719 31147 516.01 119.91 95.12 -0.334131358395947 Down 0.547021529520539 CG14818 CG14818, isoform B - - - - 32905 1238.00 4.19 5.455 0.380628952624256 Up 0.324428741249505 Mec2 Mec2 K03364|1|7e-18|91.7|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0044464//cell part - - 42672 3532.51 17.235 14.92 -0.208093763112032 Down 0.333707568352926 loco locomotion defects, isoform H K07524|1|2e-23|112|gga:395110|regulator of G-protein signalling 3 GO:0044448//cell cortex part;GO:0016020//membrane;GO:0044448//cell cortex part;GO:0016020//membrane;GO:0044448//cell cortex part;GO:0016020//membrane GO:0008047//enzyme activator activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0003006//developmental process involved in reproduction;GO:0008104//protein localization;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0003006//developmental process involved in reproduction;GO:0008104//protein localization;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045165//cell fate commitment;GO:0030036//actin cytoskeleton organization;GO:0021782//glial cell development;GO:0003006//developmental process involved in reproduction;GO:0008104//protein localization;GO:0007300//ovarian nurse cell to oocyte transport 45467 4955.58 144.54 162.23 0.166571831792205 Up 0.378648791441025 mtd mustard, isoform Z K12587|1|1e-41|172|bfo:BRAFLDRAFT_124886|exosome complex component MTR3, animal type - - GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process;GO:0009056//catabolic process 40536 1034.00 0.81 1.28 0.660149997115375 Up 0.217408532558447 CG14644 CG14644, isoform B K03364|1|9e-16|84.3|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0016020//membrane - GO:0006909//phagocytosis 34738 6433.00 36.42 40.39 0.149267223726248 Up 0.315546162990358 CG43778 CG43778, isoform D - - - - 34472 2866.50 52.16 47.36 -0.139274788602128 Down 0.309800554748382 CG7300 CG7300, isoform D - - - - 40416 780.00 0.265 0.24 -0.142957953842043 Down 0.049861312904504 CG14570 CG14570 - - - - 38985 3339.34 31.745 37.855 0.253954490286833 Up 0.432307489103157 CG6282 CG6282, isoform D - GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane;GO:0044424//intracellular part;GO:0031224//intrinsic to membrane GO:0016491//oxidoreductase activity;GO:0016491//oxidoreductase activity;GO:0016491//oxidoreductase activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process;GO:0044238//primary metabolic process 318920 680.00 0.53 0.33 -0.683526335204746 Down 0.137564390437195 CG31730 CG31730 K00670|1|9e-91|332|dme:Dmel_CG31730|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0016407//acetyltransferase activity - 42315 1033.00 1.83 3.285 0.844049722038287 Up 0.394861973319244 CG3581 CG3581 K11665|1|8e-57|220|dwi:Dwil_GK13479|DNA helicase INO80 [EC:3.6.1.-] - - - 36778 3370.65 79.705 47.62 -0.743102608613075 Down 0.684982168802008 Asph aspartyl beta-hydroxylase, isoform L K00476|1|9e-99|362|ecb:100065909|aspartate beta-hydroxylase [EC:1.14.11.16] GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0031227//intrinsic to endoplasmic reticulum membrane;GO:0031227//intrinsic to endoplasmic reticulum membrane GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 34696 1207.00 23.255 23.315 0.00371748981528338 Up 0.0444128912957337 CG12404 CG12404 K12603|1|4e-35|149|phu:Phum_PHUM129580|CCR4-NOT transcription complex subunit 6 [EC:3.1.-.-];K01887|2|2e-11|70.1|hmg:100214624|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0044464//cell part - - 36129 1400.22 239.825 296.5 0.306050047786962 Up 0.541044776119403 CG7220 CG7220, isoform F K10688|1|2e-84|313|der:Dere_GG20145|ubiquitin-conjugating enzyme E2 W [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process;GO:0060255;GO:0006464//cellular protein modification process 43462 4858.67 15.465 17.965 0.2161821019129 Up 0.347411174217409 CG15817 CG15817, isoform E K11832|1|0.0|1607|dme:Dmel_CG15817|ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity - 31158 1718.30 11.155 11.37 0.0275417406481076 Up 0.0779949808479725 CG11596 CG11596, isoform E - - - - 19835643 604.00 0.14 0.23 0.716207033999409 Up 0.0961894069475631 35066 1119.20 21 23.64 0.170840707624047 Up 0.315579183727381 Oli olig family, isoform D K09086|1|2e-30|132|gga:395164|class B basic helix-loop-helix protein 4/5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression;GO:0010468//regulation of gene expression 318847 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG31613 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 5740536 1034.37 32.63 28.345 -0.203104718272438 Down 0.371516312244089 CG34310 CG34310, isoform D - - - - 38187 1314.44 13.735 12.86 -0.0949662677479088 Down 0.17203803988905 CG12104 CG12104, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - 32615 1899.58 48.18 47.98 -0.00600123594503594 Down 0.0608572183331132 CG9947 CG9947, isoform B - GO:0044464//cell part - - 19835773 467.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 38283 1383.59 18.535 19.115 0.0444530850154933 Up 0.11144498745212 CG9018 CG9018, isoform B - - - - 33791 1230.44 1.14 1.91 0.744538813871007 Up 0.289889050323603 CG7251 CG7251, isoform B - - - - 3346208 3031.01 12.88 12.42 -0.0524674198941355 Down 0.113393210936468 dpr3 dpr3, isoform D - - - - 31430 10706.97 7.085 7.82 0.142400754389334 Up 0.192576938317263 CG32767 CG32767, isoform H K09228|1|2e-36|155|mcc:713527|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 39178 1618.00 0.075 0.03 -1.32192809488736 Down 0.0800752872804121 CG32053 CG32053 - GO:0031224//intrinsic to membrane - GO:0006810//transport 40751 2302.00 0.1 0.135 0.432959407276106 Up 0.0678576145819575 CG1077 CG1077 K06254|1|5e-06|53.5|mcc:700400|agrin - - - 48337 725.00 0.39 0.28 -0.478047296804644 Down 0.0999867917051909 GstD4 glutathione S transferase D4 K00799|1|3e-122|437|dme:Dmel_CG11512|glutathione S-transferase [EC:2.5.1.18] - GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity - 39799 801.00 5.77 4.18 -0.4650683765646 Down 0.371021001188747 CG13062 CG13062 - - - - 19834781 790.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 5740367 931.00 50.07 77.64 0.632853662629909 Up 0.659490159820367 43517 2720.00 2.85 2.47 -0.206450877467427 Down 0.154041738211597 ncd non-claret disjunctional, isoform B K10405|1|0.0|1257|dme:Dmel_CG7831|kinesin family member C1 GO:0005871//kinesin complex GO:0003777//microtubule motor activity;GO:0042802//identical protein binding;GO:0032559 GO:0000022//mitotic spindle elongation;GO:0045132//meiotic chromosome segregation;GO:0000212//meiotic spindle organization;GO:0051012//microtubule sliding;GO:0007143//female meiosis;GO:0007067//mitosis 317964 819.25 1.47 1.525 0.0529930876138844 Up 0.0566966054682341 CG32299 CG32299, isoform B - - - - 38133 2974.00 1.44 1.655 0.200762405364905 Up 0.114747061154405 CG9194 CG9194 K05323|1|4e-16|87.4|cel:C52B9.6|potassium channel subfamily K, invertebrate;K04919|3|2e-15|85.1|rno:84429|potassium channel subfamily K member 9 - - - 41036 1908.00 6.29 6.475 0.0418201756946269 Up 0.0776317527407212 CG11760 CG11760 - - - - 37002 371.00 1.075 0.135 -2.99330534742599 Down 0.39400343415665 Oxp oxpecker K11585|1|1e-09|61.2|dre:326746|chromobox protein 1;K11587|3|6e-09|58.9|dme:Dmel_CG8409|chromobox protein 5 - - - 326111 1766.00 0.05 0.41 3.03562390973072 Up 0.25 CG31013 CG31013 K00472|1|4e-120|432|dvi:Dvir_GJ22993|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 38101 2717.00 19.835 23.945 0.271676038090721 Up 0.421674811781799 dpr20 dpr20 - - - - 318164 1976.54 19.63 22.67 0.207724218274615 Up 0.357119270902127 lawc leg arista wing complex, isoform D - - - - 19835470 1609.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 19836022 316.00 0.445 0.38 -0.227805917522812 Down 0.0703011491216484 32460 2315.00 1.655 1.99 0.265937213736431 Up 0.154041738211597 CG9114 CG9114 - - - - 42700 2272.00 6.56 6.755 0.0422599547076006 Up 0.0795799762250693 CG4723 CG4723 K01415|1|6e-49|196|dme:Dmel_CG14527|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|5e-35|149|api:100162251|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41801 1142.00 12.4 13.785 0.152759146735953 Up 0.250099062211069 CycC cyclin C K06634|1|2e-13|77.0|tca:661731|cyclin H - - - 42830 666.00 0.85 0.74 -0.199937570508752 Down 0.0854576674151367 RpS19b ribosomal protein S19b, isoform C K02966|1|6e-83|306|dme:Dmel_CG5338|small subunit ribosomal protein S19e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 34669 3473.85 1.09 1.035 -0.0746973672776013 Down 0.0583476423193766 nub nubbin, isoform E K09364|1|0.0|799|dsi:Dsim_GD23844|POU domain transcription factor, class 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0006355//regulation of transcription, DNA-dependent;GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0006355//regulation of transcription, DNA-dependent 14462646 400.00 0.11 0.125 0.184424571137428 Up 0.0511161009113723 36049 3072.00 2.445 2.365 -0.0479942816128385 Down 0.0613855501254788 CG2292 CG2292 K05285|1|0.0|1665|dme:Dmel_CG2292|phosphatidylinositol glycan, class N [EC:2.7.-.-] GO:0031090//organelle membrane GO:0016301//kinase activity;GO:0032559 GO:0006497//protein lipidation 3346176 1690.00 2.76 2.66 -0.0532420212769792 Down 0.0653810593052437 U3-55K U3 small nuclear riboprotein factor 55K K03130|1|4e-15|83.2|isc:IscW_ISCW022714|transcription initiation factor TFIID subunit D4;K01062|5|2e-14|80.5|smm:Smp_129340|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - - - 38011 3476.35 1.27 0.99 -0.359328066692556 Down 0.150508519350152 CG9380 CG9380, isoform G K01446|1|8e-06|53.1|mcc:718287|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0044464//cell part GO:0046914//transition metal ion binding - 38954 2688.63 27.865 20.86 -0.41771499555834 Down 0.539129573372078 CG7120 CG7120, isoform G - - - - 31552 1907.00 0.045 0.17 1.91753783980803 Up 0.124157971205917 Btd biotinidase K01435|1|5e-86|318|dme:Dmel_CG32754|biotinidase [EC:3.5.1.12];K08069|3|6e-39|162|nve:NEMVE_v1g122468|pantetheine hydrolase [EC:3.5.1.92] - - - 31252 1013.00 325.98 7.875 -5.37135971911784 Down 0.912329943204332 CG2650 CG2650 - - - - 5740812 1051.00 124.49 137.845 0.147017079441303 Up 0.346189406947563 246442 1794.00 1.015 1.72 0.760928837516922 Up 0.27734117025492 Ir51b ionotropic receptor 51b - - - - 40399 3136.00 5.86 6.89 0.233603318282044 Up 0.255976753401136 S1P S1P K01342|1|0.0|1889|dme:Dmel_CG7169|subtilisin [EC:3.4.21.62];K08653|2|0.0|878|tca:100142346|membrane-bound transcription factor protease, site 1 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0051605 42163 1468.00 0.445 0.55 0.305626282558262 Up 0.0941421212521464 CG14316 CG14316 - - - - 31272 966.00 0.445 0.185 -1.26628006533745 Down 0.178807290978735 CG12498 CG12498 - - - - 36759 981.00 17.94 15.655 -0.196556381780591 Down 0.327070400211333 CG8320 CG8320 - - - - 3885573 5965.77 9.52 11.515 0.274480932484902 Up 0.349788667283054 Octbeta3R octopamine beta3 receptor, isoform K K04160|1|3e-38|162|oaa:100075879|5-hydroxytryptamine (serotonin) receptor 4 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 36280 1593.00 6.225 3.17 -0.973590996816036 Down 0.527935543521331 RnrS ribonucleoside diphosphate reductase small subunit K10808|1|0.0|740|dme:Dmel_CG8975|ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] GO:0043234//protein complex;GO:0044424//intracellular part GO:0046872//metal ion binding;GO:0016728 GO:0006259//DNA metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0051262//protein tetramerization;GO:0009132//nucleoside diphosphate metabolic process;GO:0008283//cell proliferation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 42046 1230.00 34.065 22.435 -0.602539022751699 Down 0.620096420552107 CG17556 CG17556, isoform B - - - - 44483 3080.00 1.62 1.415 -0.195191760052742 Down 0.112468630299828 KaiRIA glutamate receptor IID K05313|1|0.0|1734|dme:Dmel_CG18039|glutamate receptor, ionotropic, invertebrate;K05202|5|6e-143|508|xla:100294518|glutamate receptor, ionotropic, kainate 2 GO:0031224//intrinsic to membrane;GO:0030313;GO:0044459//plasma membrane part GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0060024//rhythmic synaptic transmission 36470 2355.00 4.73 1.14 -2.05280635917465 Down 0.605600316999075 CG4714 CG4714 - - - - 41870 3015.00 16.685 16.1 -0.0514909981803401 Down 0.121120063399815 ldlCp ldlCp-related protein K05605|1|1e-42|175|dya:Dyak_GE24304|3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4] - - - 19835247 935.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 35121 4647.77 6.845 6.76 -0.0180272949757154 Down 0.0573900409457139 msl-1 male-specific lethal 1, isoform B K13163|1|0.0|1630|dme:Dmel_CG10385|male-specific lethal 1 GO:0000805//X chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0003676//nucleic acid binding GO:0009047//dosage compensation by hyperactivation of X chromosome 33955 1181.00 31.615 24.05 -0.394572325516592 Down 0.533549068815216 CG11236 CG11236, isoform B K00272|1|0.0|697|dme:Dmel_CG11236|D-aspartate oxidase [EC:1.4.3.1];K00273|1|0.0|697|dme:Dmel_CG11236|D-amino-acid oxidase [EC:1.4.3.3] - GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0008152//metabolic process 19835840 515.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 3772633 444.00 2.15 2.4 0.158697746019058 Up 0.117718927486461 42094 1585.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 CG17283 CG17283 K01379|1|3e-66|252|dme:Dmel_CG5863|cathepsin D [EC:3.4.23.5];K06002|1|3e-66|252|dme:Dmel_CG5863|pepsin A [EC:3.4.23.1] - - - 36955 1236.57 34.31 31.055 -0.143803558110948 Down 0.295766741513671 CG4802 methylthioadenosine phosphorylase ortholog, isoform C K00772|1|2e-168|592|dme:Dmel_CG4802|5'-methylthioadenosine phosphorylase [EC:2.4.2.28] - - - 32970 5263.00 4.225 4.425 0.0667261138008132 Up 0.0883304715361247 Ranbp21 Ranbp21, isoform B - - GO:0022892 GO:0015031//protein transport 32385 1156.00 96.555 32.995 -1.54910355181693 Down 0.760830801743495 CG9400 CG9400 K02330|1|8e-16|84.7|tca:656359|DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-];K00747|4|4e-11|68.9|tca:656110|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] - - - 37876 3956.00 22.96 21.405 -0.101174806478768 Down 0.211960110949676 CG3356 CG3356 K10589|1|0.0|2024|dme:Dmel_CG3356|ubiquitin-protein ligase E3 C [EC:6.3.2.19] GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification 37959 1542.00 15.06 16.65 0.144800407286696 Up 0.252905824858011 CG3894 CG3894 K01931|1|2e-19|97.1|tad:TRIADDRAFT_55615|protein neuralized - - - 36653 3690.00 1.545 2.295 0.570887315509433 Up 0.271496499801876 SMC2 SMC2 K06674|1|0.0|2235|dme:Dmel_CG10212|structural maintenance of chromosome 2 GO:0043234//protein complex;GO:0000793//condensed chromosome;GO:0015630//microtubule cytoskeleton GO:0003676//nucleic acid binding;GO:0032559 GO:0000070//mitotic sister chromatid segregation 12798544 1450.00 0.035 0.035 0 - 0.0382380134724607 CG43337 CG43337, isoform B - - - - 34253 527.00 0.62 1.385 1.15954585566231 Up 0.31151763307357 CG13110 CG13110 - - - - 31439 2628.00 0.655 1.36 1.05403983971289 Up 0.295403513406419 CG3323 CG3323 - - - - 41709 3609.43 33.51 27.51 -0.28463554688826 Down 0.45598335754854 foxo forkhead box, sub-group O, isoform G K07201|1|4e-54|214|oaa:100082288|forkhead box protein O1 - - - 44724 808.00 31.275 31.445 0.00782075119762109 Up 0.0594703473781535 san separation anxiety K00670|1|4e-07|55.1|cel:K07H8.3|peptide alpha-N-acetyltransferase [EC:2.3.1.88] GO:0008278//cohesin complex GO:0004596//peptide alpha-N-acetyltransferase activity GO:0000070//mitotic sister chromatid segregation 3885602 566.00 0.93 1.36 0.548304030142308 Up 0.201558578787479 CG34033 CG34033 - - - GO:0048609//multicellular organismal reproductive process 47869 5867.00 4.5 4.38 -0.0389941316158637 Down 0.0677255316338661 vir virilizer K03350|1|5e-53|211|nvi:100123129|anaphase-promoting complex subunit 3 GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0043484//regulation of RNA splicing;GO:0007297//ovarian follicle cell migration;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0040029//regulation of gene expression, epigenetic;GO:0007538//primary sex determination 19835073 321.00 0.855 0.01 -6.4178525148859 Down 0.466682076343944 38932 2278.00 7.19 6.585 -0.126808330182783 Down 0.171245542200502 CG13671 CG13671 - - - - 38430 5430.71 12.85 12.07 -0.090342683326219 Down 0.166259410910052 CG42324 CG42324, isoform K K08820|1|2e-16|88.6|dwi:Dwil_GK20517|PCTAIRE protein kinase [EC:2.7.11.22];K06105|2|3e-13|77.8|mmu:74094|tight junction protein 4 (peripheral) - GO:0005506//iron ion binding;GO:0004672//protein kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 36767 921.00 82.88 81.335 -0.0271476979500296 Down 0.110124157971206 CG8397 CG8397 - - GO:0005488//binding - 34729 909.14 640.85 659.145 0.0406091538161084 Up 0.139776779817726 CG5945 CG5945, isoform B - - - - 40659 3971.82 13.72 16.495 0.265748296392118 Up 0.386738872011623 Hcs holocarboxylase synthetase, isoform D K01942|1|0.0|1969|dme:Dmel_CG14670|biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15] GO:0005694//chromosome GO:0018271//biotin-protein ligase activity GO:0006950//response to stress;GO:0043412//macromolecule modification 41958 3781.00 1.115 0.83 -0.42586046857338 Down 0.154636111478008 Sb stubble, isoform B K01312|1|2e-150|533|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|3|4e-41|171|ssc:397144|plasma kallikrein [EC:3.4.21.34] - - - 35537 1075.00 10.58 11.59 0.131540938892446 Up 0.211596882842425 CG7849 CG7849 K03177|1|2e-40|166|xtr:496499|tRNA pseudouridine synthase B [EC:5.4.99.12] - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0010467//gene expression;GO:0009451//RNA modification 14462701 2421.85 41.895 43.49 0.0539056344629623 Up 0.145720512481839 CG44000 CG44000, isoform F - - - - 38026 1426.92 63.785 60.82 -0.068671376117526 Down 0.188911636507727 Mtch mitochondrial carrier homolog 1, isoform G - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity;GO:0005215//transporter activity;GO:0005215//transporter activity GO:0006810//transport;GO:0006810//transport;GO:0006810//transport 34974 6489.35 14.875 15.9 0.0961370970890495 Up 0.189539030511161 chif chiffon, isoform D K06629|1|1e-11|73.9|xla:398599|activator of S phase kinase - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0003006//developmental process involved in reproduction;GO:0006260//DNA replication;GO:0006277//DNA amplification;GO:0003006//developmental process involved in reproduction 8673970 460.00 344.025 302.545 -0.185363665924166 Down 0.414113063003566 CG40472 CG40472 K03958|1|2e-54|210|dme:Dmel_CG40002|NADH dehydrogenase (ubiquinone) 1 beta subcomplex 2 [EC:1.6.5.3 1.6.99.3] - - - 34940 611.00 0.92 0.52 -0.823122237915921 Down 0.209813763043191 CG13244 CG13244 - - - - 42863 2380.00 11.905 12.845 0.109639269630483 Up 0.191091005151235 sec10 Sec10 ortholog - GO:0043234//protein complex;GO:0044424//intracellular part - GO:0006903//vesicle targeting;GO:0006904//vesicle docking involved in exocytosis 19834986 5175.80 0.51 1.025 1.00705475753395 Up 0.252872804120988 40388 1356.00 116.895 75.375 -0.633055220049814 Down 0.668702945449742 Pros54 regulatory particle non-ATPase 10, isoform B K03029|1|1e-170|599|dme:Dmel_CG7619|26S proteasome regulatory subunit N10 GO:0005838//proteasome regulatory particle GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding GO:0006259//DNA metabolic process;GO:0010468//regulation of gene expression;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process 41844 1169.00 23.72 25.695 0.115383642259152 Up 0.247457403249241 Set Set K11290|1|1e-124|446|dme:Dmel_CG4299|template-activating factor I - - - 3772620 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 39677 741.00 0.78 0.445 -0.809668787895851 Down 0.191619336943601 mex1 midgut expression 1, isoform C - GO:0031224//intrinsic to membrane GO:0046914//transition metal ion binding;GO:0015002//heme-copper terminal oxidase activity GO:0048565//digestive tract development;GO:0048565//digestive tract development;GO:0006091//generation of precursor metabolites and energy 3772517 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33860 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 31833 2043.00 3.72 3.965 0.0920182445959468 Up 0.0993593977017567 CG7246 CG7246 - GO:0044464//cell part - GO:0010467//gene expression 43749 9590.18 29.325 33.65 0.198475396581809 Up 0.372242768458592 faf fat facets, isoform I K11840|1|0.0|4944|dme:Dmel_CG1945|ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.1.2.15] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity GO:0016192//vesicle-mediated transport;GO:0007276//gamete generation;GO:0040023//establishment of nucleus localization;GO:0001745//compound eye morphogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0070646//protein modification by small protein removal;GO:0016192//vesicle-mediated transport;GO:0007276//gamete generation;GO:0040023//establishment of nucleus localization;GO:0001745//compound eye morphogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0070646//protein modification by small protein removal 36844 2055.00 6.29 9.42 0.582667042733494 Up 0.491414608374059 S-Lap8 Sperm-Leucylaminopeptidase 8 K01255|1|0.0|1045|dse:Dsec_GM21704|leucyl aminopeptidase [EC:3.4.11.1] GO:0044424//intracellular part GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process 41222 1241.98 2.07 3.045 0.556811460407007 Up 0.305408796724343 CG5359 CG5359, isoform C K11806|1|4e-18|91.3|dsi:Dsim_GD14543|WD repeat and SOF domain-containing protein 1;K10420|2|1e-07|56.2|dre:565740|dynein light chain Tctex-type 1 - - - 34065 2150.05 38.535 37.25 -0.0489289653850866 Down 0.142253335094439 Herp Homocysteine-induced endoplasmic reticulum protein, isoform C K14027|1|2e-14|81.6|rno:85430|homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - GO:0006984//ER-nucleus signaling pathway;GO:0006984//ER-nucleus signaling pathway 37707 2945.03 60.43 68.91 0.189448415399409 Up 0.389842821291771 CG3530 CG3530, isoform C K01112|1|0.0|1496|dpo:Dpse_GA17504| [EC:3.1.3.-] - GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007049//cell cycle;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process 37987 1100.54 38.54 29.5 -0.385641617159155 Down 0.544511953506802 CG3760 CG3760, isoform D - - - - 41780 1279.00 0.095 0.6 2.65896308216493 Up 0.290582485801083 CG3509 histone H1 variant BigH1 - - - - 19835788 1335.00 0.035 0.1 1.51457317282976 Up 0.0866464139479593 41076 857.00 0.65 0.48 -0.437405312307298 Down 0.120492669396381 CG11977 CG11977 - - - - 32374 1172.00 0.135 0.18 0.415037499278844 Up 0.0678576145819575 CG11674 CG11674 K06252|1|1e-09|61.6|rno:116640|tenascin GO:0030529//ribonucleoprotein complex - GO:0000377 36566 1460.00 16.515 18 0.124219936931512 Up 0.22995641262713 CG8323 CG8323 K03454|1|5e-172|603|dme:Dmel_CG8323|mitochondrial carrier protein, MC family GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 7354408 640.00 0.65 0.74 0.187085552600495 Up 0.078985602958658 CG42364 CG42364 - - - - 37899 1390.00 0.06 0.25 2.05889368905357 Up 0.162561088363492 Pgam5-2 phosphoglycerate mutase 5-2 K01834|1|9e-41|167|mcc:693782|phosphoglycerate mutase [EC:5.4.2.1];K13347|2|1e-39|164|ecb:100061603|peroxisomal membrane protein 2 GO:0044464//cell part - - 34877 1769.00 6 5.955 -0.0108609926317668 Down 0.0472856954167217 l(2)35Bd lethal (2) 35Bd K00565|1|0.0|882|dme:Dmel_CG3688|mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016741 GO:0006397//mRNA processing 38301 616.00 86.515 90.58 0.0662422499971276 Up 0.192808083476423 CG8993 CG8993 K03671|1|2e-67|254|dsi:Dsim_GD13682|thioredoxin 1 GO:0043231//intracellular membrane-bounded organelle GO:0015036//disulfide oxidoreductase activity GO:0018904;GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis 37083 1671.00 1.345 1.29 -0.0602351071333699 Down 0.0554748381983886 nopo no poles, isoform B K11985|1|0.0|756|dme:Dmel_CG5140|TRAF-interacting protein - - - 318791 1803.00 0.285 0.545 0.935294310612185 Up 0.169825650508519 CG31542 CG31542, isoform C - - - - 43007 1178.91 1.495 3.465 1.21270986793911 Up 0.472592788271034 CG11836 CG11836, isoform I K01312|1|6e-43|174|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K09636|2|4e-41|168|dre:569688|transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-];K09634|3|2e-40|166|tgu:100220345|transmembrane protease, serine 3 [EC:3.4.21.-];K08670|4|1e-39|164|mdo:100021603|suppressor of tumorigenicity protein 14 [EC:3.4.21.109];K09635|5|3e-39|162|dre:777630|transmembrane protease, serine 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 35285 837.00 0.845 0.215 -1.97461468158009 Down 0.306927750627394 CG10659 CG10659 K00669|1|5e-16|84.7|dme:Dmel_CG3318|arylalkylamine N-acetyltransferase [EC:2.3.1.87] - GO:0016407//acetyltransferase activity - 3885585 4560.00 0.095 0.135 0.506959988719883 Up 0.0682868841632545 CG34027 CG34027 K11657|1|1e-06|56.6|aag:AaeL_AAEL008063|remodeling and spacing factor 1 - GO:0016740//transferase activity - 35655 1449.00 0.695 0.455 -0.611146432524811 Down 0.148659358076872 Gr43a gustatory receptor 43a, isoform C K08471|1|0.0|797|dme:Dmel_CG1712|gustatory receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 42087 2704.15 11.245 11.09 -0.020024295616107 Down 0.0657773081495179 Brf Brf, isoform B K03124|1|7e-18|92.8|xtr:549031|transcription initiation factor TFIIB GO:0005667//transcription factor complex GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding GO:0006412//translation;GO:0006355//regulation of transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process 5740657 1460.00 0.09 0.195 1.11547721741994 Up 0.107647602694492 43738 835.00 12.71 11.915 -0.0931850788146882 Down 0.167481178179897 CG1896 CG1896 - - - - 14462877 790.00 0.105 0.07 -0.584962500721156 Down 0.0622440892880729 36654 950.00 1.575 2.63 0.739710970905023 Up 0.335325584467045 Ercc1 Ercc1 K10849|1|7e-147|519|dme:Dmel_CG10215|DNA excision repair protein ERCC-1 GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0004518//nuclease activity GO:0033683//nucleotide-excision repair, DNA incision;GO:0006310//DNA recombination 38226 12090.00 0.105 0.16 0.60768257722124 Up 0.075023114515916 Dhc62B dynein heavy chain at 62B K10408|1|0.0|3014|tgu:100230839|dynein heavy chain, axonemal GO:0030286//dynein complex GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 50096 493.00 39.465 47.875 0.278698737812636 Up 0.473946638488971 Spase12 spase 12-subunit K12946|1|4e-42|169|dme:Dmel_CG11500|signal peptidase complex subunit 1 [EC:3.4.-.-];K01423|2|4e-35|146|dpo:Dpse_GA11036| [EC:3.4.-.-] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane GO:0016787//hydrolase activity GO:0051605 19835191 339.00 0.525 0.78 0.571156701196126 Up 0.153744551578391 39343 849.00 0.92 0.995 0.113062664486636 Up 0.0651829348831066 CG5906 CG5906 K13348|1|2e-30|132|tgu:100229975|protein Mpv17;K13349|4|2e-13|76.3|aga:AgaP_AGAP012390|Mpv17-like protein GO:0031224//intrinsic to membrane - - 33809 1752.00 8.49 10.925 0.363796820834922 Up 0.410877030775327 CG7239 CG7239 - - - - 49802 367.00 418.95 464.165 0.147859667149654 Up 0.35553427552503 IM2 immune induced molecule 2 - - - GO:0006950//response to stress 53584 1740.00 0.61 0.15 -2.02384674195437 Down 0.26413287544578 Ugt37b1 UDP-glycosyltransferase 37b1 K00699|1|0.0|1043|dme:Dmel_CG9481|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 32508 2920.49 56.39 45.425 -0.311952828491893 Down 0.508519350151895 CG9281 CG9281, isoform D K06185|1|0.0|1173|dme:Dmel_CG9281|ATP-binding cassette, sub-family F, member 2 GO:0043234//protein complex;GO:0043234//protein complex GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 41670 2941.73 83.975 105.06 0.323181694032853 Up 0.536983225465592 B52 B52, isoform O K12893|1|3e-55|218|dsi:Dsim_GD18917|splicing factor, arginine/serine-rich 4/5/6 GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck GO:0003723//RNA binding;GO:0003723//RNA binding GO:0043484//regulation of RNA splicing;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0043484//regulation of RNA splicing;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly 30978 1188.00 1.22 0.355 -1.7809902180582 Down 0.351802932241448 Or1a odorant receptor 1a K08471|1|0.0|799|dme:Dmel_CG17885|gustatory receptor - - - 33293 1628.00 3.305 4.685 0.503398776151495 Up 0.353586052040682 CG4749 CG4749 K00599|1|4e-25|116|dre:553534| [EC:2.1.1.-] - - - 39183 1096.00 1.65 1.72 0.0599425404562822 Up 0.0598996169594505 CG6628 CG6628 - - - - 35904 3822.00 0.025 0.045 0.84799690655495 Up 0.0552767137762515 Np notopleural, isoform B K01312|1|7e-75|282|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K08670|2|5e-50|200|mcc:718848|suppressor of tumorigenicity protein 14 [EC:3.4.21.109] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39772 4908.06 9.66 10.68 0.144816552851781 Up 0.218267071721041 CG5151 CG5151, isoform F - - - - 3885599 1055.98 6.17 6.65 0.108083851239134 Up 0.146942279751684 CG13516 CG13516, isoform B - - - - 35244 1316.00 66.6 30.16 -1.14288574868996 Down 0.726654338924845 CG13082 CG13082 - - - - 35320 582.00 10.29 10.13 -0.0226088080928303 Down 0.0657773081495179 CG17472 CG17472 - - - - 19835620 670.00 35.42 29.76 -0.251189685643883 Down 0.428146876238278 14462696 1071.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 38574 682.00 0.295 0.265 -0.154722594798642 Down 0.0552767137762515 CG13712 CG13712 - - - - 3885633 1202.00 0.165 0.295 0.838248930003388 Up 0.115935807687228 CG34025 CG34025 - - - - 10178955 792.51 2.71 5.465 1.01192864431803 Up 0.517236824725928 43183 2083.16 1002.6 979.43 -0.0337318475606392 Down 0.117487782327302 Ald aldolase, isoform M K01623|1|0.0|691|dse:Dsec_GM10189|fructose-bisphosphate aldolase, class I [EC:4.1.2.13] - GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0016832//aldehyde-lyase activity;GO:0032559 GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process;GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process;GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process;GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process;GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process;GO:0006007//glucose catabolic process;GO:0009888//tissue development;GO:0000075//cell cycle checkpoint;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0007143//female meiosis;GO:0006950//response to stress;GO:0045143//homologous chromosome segregation;GO:0006464//cellular protein modification process 45969 2970.00 0.19 0.275 0.533432200081074 Up 0.0931514991414608 gwl greatwall, isoform B K08282|1|0.0|1657|dme:Dmel_CG7719|non-specific serine/threonine protein kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0051276//chromosome organization;GO:0007088//regulation of mitosis;GO:0007143//female meiosis;GO:0006464//cellular protein modification process 31867 2811.00 0.02 0.01 -1 Down 0.0497292299564126 Ir8a ionotropic receptor 8a K05313|1|0.0|1746|dme:Dmel_CG32704|glutamate receptor, ionotropic, invertebrate GO:0031224//intrinsic to membrane;GO:0030313 GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0032559;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006810//transport;GO:0006464//cellular protein modification process 40323 1987.90 15.21 16.25 0.0954195650786825 Up 0.190265486725664 CG10585 CG10585, isoform B K12505|1|0.0|858|dme:Dmel_CG10585|decaprenyl diphosphate synthase subunit 2 [EC:2.5.1.-] - GO:0003824//catalytic activity GO:0006720//isoprenoid metabolic process 12798138 1138.00 0.07 0.08 0.192645077942396 Up 0.045898824461762 CG43393 CG43393 - - - - 37947 1788.76 11.835 14.135 0.256212177096561 Up 0.360817593448686 Pof painting of fourth, isoform C - GO:0005694//chromosome;GO:0005694//chromosome GO:0005488//binding;GO:0005488//binding - 36339 1254.46 30.44 37.395 0.296877024709111 Up 0.48064984810461 Den1 deneddylase 1, isoform C K08597|1|4e-34|145|bfo:BRAFLDRAFT_221105|sentrin-specific protease 8 [EC:3.4.22.-] - GO:0019783//small conjugating protein-specific protease activity;GO:0004175//endopeptidase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0004175//endopeptidase activity GO:0070646//protein modification by small protein removal;GO:0070646//protein modification by small protein removal 36695 1566.00 0.195 0.54 1.46948528330122 Up 0.213479064852728 CG8102 CG8102, isoform B K03942|1|0.0|997|dse:Dsec_GM20146|NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0000166//nucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0000166//nucleotide binding GO:0022904//respiratory electron transport chain;GO:0022904//respiratory electron transport chain 37303 1717.00 0.16 0.495 1.62935662007961 Up 0.217837802139744 CG13871 CG13871 - - - - 34132 3659.27 20.185 14.995 -0.42880206461177 Down 0.517302866199974 Btk29A Btk family kinase at 29A, isoform H K07364|1|0.0|1174|dme:Dmel_CG8049|tec protein tyrosine kinase [EC:2.7.10.2] GO:0016020//membrane;GO:0044424//intracellular part;GO:0045171//intercellular bridge;GO:0016020//membrane;GO:0044424//intracellular part;GO:0045171//intercellular bridge;GO:0016020//membrane;GO:0044424//intracellular part;GO:0045171//intercellular bridge;GO:0016020//membrane;GO:0044424//intracellular part;GO:0045171//intercellular bridge;GO:0016020//membrane;GO:0044424//intracellular part;GO:0045171//intercellular bridge;GO:0016020//membrane;GO:0044424//intracellular part;GO:0045171//intercellular bridge GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006810//transport;GO:0006261//DNA-dependent DNA replication;GO:0051276//chromosome organization;GO:0010259//multicellular organismal aging;GO:0008064//regulation of actin polymerization or depolymerization;GO:0046958//nonassociative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0007617//mating behavior;GO:0006810//transport;GO:0006261//DNA-dependent DNA replication;GO:0051276//chromosome organization;GO:0010259//multicellular organismal aging;GO:0008064//regulation of actin polymerization or depolymerization;GO:0046958//nonassociative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0007617//mating behavior;GO:0006810//transport;GO:0006261//DNA-dependent DNA replication;GO:0051276//chromosome organization;GO:0010259//multicellular organismal aging;GO:0008064//regulation of actin polymerization or depolymerization;GO:0046958//nonassociative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0007617//mating behavior;GO:0006810//transport;GO:0006261//DNA-dependent DNA replication;GO:0051276//chromosome organization;GO:0010259//multicellular organismal aging;GO:0008064//regulation of actin polymerization or depolymerization;GO:0046958//nonassociative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0007617//mating behavior;GO:0006810//transport;GO:0006261//DNA-dependent DNA replication;GO:0051276//chromosome organization;GO:0010259//multicellular organismal aging;GO:0008064//regulation of actin polymerization or depolymerization;GO:0046958//nonassociative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0007617//mating behavior;GO:0006810//transport;GO:0006261//DNA-dependent DNA replication;GO:0051276//chromosome organization;GO:0010259//multicellular organismal aging;GO:0008064//regulation of actin polymerization or depolymerization;GO:0046958//nonassociative learning;GO:0001700//embryonic development via the syncytial blastoderm;GO:0006464//cellular protein modification process;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007484//imaginal disc-derived genitalia development;GO:0007293//germarium-derived egg chamber formation;GO:0000165//MAPK cascade;GO:0007617//mating behavior 117361 7693.95 4.525 3.43 -0.399709215797756 Down 0.305672962620526 v(2)k05816 v(2)k05816, isoform B K00665|1|0.0|4642|dme:Dmel_CG3524|fatty acid synthase, animal type [EC:2.3.1.85] GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0022892;GO:0016787//hydrolase activity;GO:0004312//fatty acid synthase activity GO:0008152//metabolic process 50263 1318.00 15.795 11.815 -0.418848307773026 Down 0.485999207502311 gk geko - - - GO:0030534//adult behavior;GO:0007606//sensory perception of chemical stimulus 37637 947.28 20.475 23.79 0.216491819896763 Up 0.37036058644829 asrij asrij, isoform B - - - - 3772235 140.00 0.45 0.47 0.0627357553479627 Up 0.0455355963545106 34678 898.00 1.91 2.62 0.455994173501702 Up 0.254358737287016 CG5781 CG5781 - - GO:0005488//binding - 31246 2427.00 2.315 1.605 -0.528438896137933 Down 0.260566635847312 brv3 brivido-3, isoform C K04990|1|2e-20|101|cfa:486838|polycystin 2L1 - - - 318960 509.00 1.765 1.905 0.110122814222142 Up 0.0833443402456743 CG31816 CG31816 - - - - 39602 694.00 2.395 0.895 -1.42006606847192 Down 0.435048210276053 CG13476 CG13476 - - - - 3885590 543.00 0.155 0.185 0.255257055242075 Up 0.0589420155857879 CG33632 CG33632 K09255|1|1e-21|102|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|1e-13|75.5|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - GO:0009987//cellular process 43360 1053.00 0.225 0.13 -0.791413378188582 Down 0.0976092986395456 CG4815 CG4815 K08667|1|2e-17|90.1|ecb:100146510|kallikrein 6 (neurosin, zyme) [EC:3.4.21.-];K08668|3|2e-16|86.7|cfa:611780|kallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117];K09623|4|2e-16|86.7|hsa:55554|kallikrein 15 [EC:3.4.21.-];K08650|5|2e-16|86.3|rno:308565|kallikrein 8 (neuropsin/ovasin) [EC:3.4.21.118] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 40470 992.00 2.335 1.405 -0.732852419488736 Down 0.314951789723947 CG11437 CG11437 K01080|1|2e-148|525|dme:Dmel_CG11437|phosphatidate phosphatase [EC:3.1.3.4] GO:0044464//cell part GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process 53501 1737.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 Ugt86Dj Ugt86Dj K00699|1|0.0|1035|dme:Dmel_CG15902|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 246656 877.96 64.725 56.17 -0.204523257208863 Down 0.400937788931449 CG30503 CG30503, isoform B K01047|1|7e-38|157|dme:Dmel_CG11124|phospholipase A2 [EC:3.1.1.4] GO:0044464//cell part GO:0046872//metal ion binding;GO:0004091//carboxylesterase activity;GO:0032561//guanyl ribonucleotide binding;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity GO:0006629//lipid metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0019637//organophosphate metabolic process;GO:0019637//organophosphate metabolic process;GO:0006629//lipid metabolic process 19835415 733.00 0.11 0.065 -0.758991900496205 Down 0.0694426099590543 34291 1805.00 50.7 37.335 -0.441457016188511 Down 0.583575485404834 Cyp4e3 cytochrome P450-4e3 K00517|1|0.0|1040|dme:Dmel_CG4105| [EC:1.14.-.-] GO:0044444//cytoplasmic part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 8674018 3446.00 0.04 0.03 -0.415037499278844 Down 0.0473847576277902 CG42505 CG42505 K03364|1|2e-12|75.5|dpo:Dpse_GA14145|cell division cycle 20-like protein 1, cofactor of APC complex GO:0044464//cell part - - 14462545 569.00 0.01 0.35 5.12928301694497 Up 0.297120591731607 35687 1989.90 229.97 164.725 -0.481386144518105 Down 0.634064192312772 CG1600 death resistor Adh domain containing target, isoform D K13953|1|4e-27|123|cin:100187292|alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1];K00665|4|8e-06|52.4|aga:AgaP_AGAP008468|fatty acid synthase, animal type [EC:2.3.1.85];K00344|5|8e-06|52.4|mmu:12972|NADPH2:quinone reductase [EC:1.6.5.5] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress;GO:0008152//metabolic process;GO:0006950//response to stress 14462522 598.00 0.21 0.575 1.45317262816561 Up 0.219753004887069 41916 863.00 0.23 0.355 0.626185163447669 Up 0.106656980583807 CG43317 CG43317 - - - - 47878 2401.30 50.55 56.22 0.153372361589966 Up 0.327367586844538 Eip63F-1 Ecdysone-induced protein 63F 1, isoform D K02183|1|1e-19|98.6|rno:364774|calmodulin GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0048102//autophagic cell death;GO:0048102//autophagic cell death;GO:0048102//autophagic cell death;GO:0048102//autophagic cell death 37163 1782.00 35.215 30.92 -0.187649763464491 Down 0.362468630299828 Cyp12b2 Cyp12b2 K00517|1|0.0|1093|dme:Dmel_CG15077| [EC:1.14.-.-];K07436|5|8e-48|191|mmu:13081|cytochrome P450, family 24, subfamily A (25-hydroxyvitamin D3 24-hydroxylase) - - - 35790 3934.71 84.475 103.85 0.297904865680846 Up 0.518986923788139 Lpin lipin, isoform M - - - - 44276 2455.00 0.645 1.015 0.654108661761922 Up 0.190628714832915 Crtp Caldesmon-related protein K05702|1|1e-08|62.0|hmg:100201659|afadin;K03254|5|4e-07|57.4|aga:AgaP_AGAP002340|translation initiation factor eIF-3 subunit 10 - - - 246420 1062.00 72.385 138.64 0.937580889063633 Up 0.72057852331264 CG30054 CG30054, isoform F K04634|1|0.0|636|dme:Dmel_CG30054|guanine nucleotide binding protein (G protein), alpha q polypeptide GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane;GO:0016028//rhabdomere;GO:0019897//extrinsic to plasma membrane GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0016198//axon choice point recognition;GO:0002251;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0007606//sensory perception of chemical stimulus 32013 847.00 52.775 45.21 -0.223212755915538 Down 0.416721701228371 CG17333 CG17333 K01057|1|5e-118|423|dme:Dmel_CG17333|6-phosphogluconolactonase [EC:3.1.1.31] - GO:0004091//carboxylesterase activity GO:0006007//glucose catabolic process 40977 1122.00 0.605 0.385 -0.652076696579693 Down 0.143574164575353 CG11672 CG11672, isoform B - - - - 44643 2488.54 89.92 96.575 0.103007736898367 Up 0.252806762646942 Cnx99A calnexin 99A, isoform E K08054|1|0.0|1089|dme:Dmel_CG11958|calnexin GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 10178876 841.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 40833 4068.32 8.58 6.3 -0.445625819112267 Down 0.421872936203936 Scr Sex combs reduced, isoform B K09311|1|4e-133|458|dse:Dsec_GM10524|Antp family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007423//sensory organ development;GO:0045449;GO:0006351//transcription, DNA-dependent;GO:0007379//segment specification;GO:0007423//sensory organ development;GO:0045449;GO:0006351//transcription, DNA-dependent;GO:0007379//segment specification 43323 946.43 1203.815 850.215 -0.501714081301056 Down 0.648791441024964 Mlc1 myosin alkali light chain 1, isoform D K01376|1|4e-67|254|dpo:Dpse_GA18996| [EC:3.4.22.-];K05738|2|5e-19|95.1|oaa:100077064|myosin light chain 1 GO:0016460//myosin II complex;GO:0016460//myosin II complex GO:0046872//metal ion binding;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0046872//metal ion binding;GO:0016887//ATPase activity;GO:0003774//motor activity GO:0009888//tissue development;GO:0003012//muscle system process;GO:0009888//tissue development;GO:0003012//muscle system process 37106 831.00 108.635 153.29 0.4967745994619 Up 0.636672830537578 GstE1 glutathione S transferase E1 K00799|1|1e-126|452|dme:Dmel_CG5164|glutathione S-transferase [EC:2.5.1.18] - - - 43634 2181.87 0.715 0.575 -0.314381285834014 Down 0.104015321621979 CG9702 CG9702, isoform C K04602|1|1e-34|148|gga:416011|cadherin EGF LAG seven-pass G-type receptor 3 (flamingo);K03321|2|2e-32|141|rno:64076|sulfate permease, SulP family;K13962|3|3e-31|137|tgu:100223009|solute carrier family 26 (sulfate anion transporter), member 7 GO:0031224//intrinsic to membrane - GO:0006810//transport 33610 2456.61 15.895 19.41 0.288227101575688 Up 0.421641791044776 Cep97 Cep97, isoform D K11293|1|1e-16|89.0|cbr:CBG03541|protein HIRA/HIR1;K01768|3|1e-16|89.0|mcc:700574|adenylate cyclase [EC:4.6.1.1] - GO:0005488//binding;GO:0005488//binding GO:0007017//microtubule-based process;GO:0007017//microtubule-based process 318939 2462.00 0.445 0.46 0.0478285250906152 Up 0.0451063267732136 CG31784 CG31784 K11499|1|5e-06|53.5|mcc:709000|centromere protein F - - - 31123 3151.00 3.55 4.335 0.288212968829791 Up 0.243032624488179 CG14797 CG14797, isoform C - - - - 326158 2242.00 1.31 1.2 -0.126532405928932 Down 0.0797781006472064 CG31759 CG31759, isoform D K12603|1|3e-31|137|dre:560386|CCR4-NOT transcription complex subunit 6 [EC:3.1.-.-] - - - 38379 1949.31 8.945 8.535 -0.0676903290241702 Down 0.11943600581165 pfk piefke, isoform B K09237|1|4e-09|63.5|phu:Phum_PHUM489940|Cys2His2 zinc finger developmental/cell cycle regulator, other;K02174|2|5e-08|59.7|dme:Dmel_CG11491|broad GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome GO:0008443//phosphofructokinase activity;GO:0003676//nucleic acid binding;GO:0008443//phosphofructokinase activity;GO:0003676//nucleic acid binding GO:0016568//chromatin modification;GO:0006007//glucose catabolic process;GO:0016568//chromatin modification;GO:0006007//glucose catabolic process 34302 958.29 20.655 19.47 -0.0852381761358258 Down 0.188185180293224 CG4036 CG4036, isoform B K10766|1|4e-54|211|bfo:BRAFLDRAFT_219277|alkylated DNA repair protein alkB homolog 4 - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 12798345 1567.00 2.405 2.3 -0.064403032825667 Down 0.0690463611147801 37941 1743.00 16.415 3.18 -2.36791607928863 Down 0.742372209747722 Cyp9c1 cytochrome P450-9c1 K00517|1|0.0|1027|dme:Dmel_CG3616| [EC:1.14.-.-];K07424|3|2e-153|542|dvi:Dvir_GJ20172|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 2768986 3434.00 0.26 0.53 1.02748073642211 Up 0.178378021397438 CG33287 CG33287 - - - - 42657 1589.07 96.935 63.755 -0.604479178746988 Down 0.658961828028002 bond james bond, isoform C K10250|1|6e-51|201|rno:361895|elongation of very long chain fatty acids protein 7;K10249|2|2e-50|200|spu:593296|elongation of very long chain fatty acids protein 4 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0007051//spindle organization;GO:0033206//cytokinesis after meiosis;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007051//spindle organization;GO:0033206//cytokinesis after meiosis;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007051//spindle organization;GO:0033206//cytokinesis after meiosis;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis 32979 2524.11 10.42 11.245 0.109928383499309 Up 0.183364152687888 Mer merlin, isoform B K05762|1|1e-116|421|cin:445597|radixin;K08007|3|6e-116|418|cfa:484056|villin 2 (ezrin) GO:0043232;GO:0044459//plasma membrane part;GO:0005739//mitochondrion GO:0005515//protein binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001745//compound eye morphogenesis;GO:0045926//negative regulation of growth;GO:0046668//regulation of retinal cell programmed cell death;GO:0008283//cell proliferation;GO:0016310//phosphorylation;GO:0007635//chemosensory behavior;GO:0007154//cell communication;GO:0016197//endosomal transport;GO:0006915//apoptotic process;GO:0048232//male gamete generation;GO:0033206//cytokinesis after meiosis;GO:0016049//cell growth;GO:0007316//pole plasm RNA localization;GO:0035556//intracellular signal transduction 19836213 646.00 0.305 0.375 0.298081352932995 Up 0.0790516444327037 - CG45486 - - - - 40777 1264.00 0.035 0.01 -1.8073549220576 Down 0.0591731607449478 Osi20 osiris 20 - - - - 19835868 494.00 0.255 0.375 0.556393348524385 Up 0.105402192576938 - CG44271 - - - - 12798467 1665.00 0.05 0.24 2.26303440583379 Up 0.163287544577995 35192 2791.00 4.365 4.335 -0.00994966040760517 Down 0.0453704926693964 l(2)37Cb lethal (2) 37Cb K12813|1|0.0|1689|dme:Dmel_CG10689|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] GO:0005681//spliceosomal complex GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032559 GO:0000377 35333 2170.00 0.74 0.865 0.225174862007775 Up 0.0904437987055871 CG9316 CG9316 K10280|1|3e-09|63.9|dwi:Dwil_GK21848|F-box and leucine-rich repeat protein 14;K10279|2|1e-08|62.0|hsa:222235|F-box and leucine-rich repeat protein 13 - - - 34009 2919.00 1.875 1.48 -0.341293419754293 Down 0.179533747193237 wg wingless K03209|1|0.0|957|dme:Dmel_CG4889|wingless-type MMTV integration site family, member 1 GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0044425//membrane part;GO:0005768//endosome;GO:0031012//extracellular matrix GO:0060089;GO:0030247//polysaccharide binding;GO:0043498//cell surface binding;GO:0001664//G-protein coupled receptor binding GO:0007472//wing disc morphogenesis;GO:0007015//actin filament organization;GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0007445;GO:0035168//larval lymph gland hemocyte differentiation;GO:0001708//cell fate specification;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0048073//regulation of eye pigmentation;GO:0030035//microspike assembly;GO:0045596//negative regulation of cell differentiation;GO:0016310//phosphorylation;GO:0046669//regulation of compound eye retinal cell programmed cell death;GO:0007392;GO:0042127//regulation of cell proliferation;GO:0010551;GO:0007448//anterior/posterior pattern specification, imaginal disc;GO:0003129;GO:0043066//negative regulation of apoptotic process;GO:0000278//mitotic cell cycle;GO:0000578//embryonic axis specification;GO:0002683//negative regulation of immune system process;GO:0035146;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0042688//crystal cell differentiation;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0007365//periodic partitioning;GO:0014016//neuroblast differentiation;GO:0035287//head segmentation;GO:0010948;GO:0035051//cardiocyte differentiation 317862 1560.00 2.435 3.535 0.537788442727057 Up 0.323471139875842 CG32115 CG32115 - - - - 32506 1381.20 289.9 329.05 0.182751488467698 Up 0.399319772817329 Pis phosphatidylinositol synthase, isoform B K00999|1|2e-29|129|dme:Dmel_CG9245|CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11] GO:0044464//cell part;GO:0044464//cell part GO:0017169//CDP-alcohol phosphatidyltransferase activity;GO:0017169//CDP-alcohol phosphatidyltransferase activity GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction 35337 1267.99 23.67 23.93 0.0157606908038839 Up 0.0738343679830934 CG9319 CG9319, isoform B K01796|1|0.0|756|dme:Dmel_CG9319|alpha-methylacyl-CoA racemase [EC:5.1.99.4] - - - 39979 2112.00 2.45 2.935 0.260578754107482 Up 0.182142385418043 CG5589 CG5589 K01529|1|2e-127|456|rno:85432| [EC:3.6.1.-] - GO:0032559;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity - 19835255 365.00 0.88 0.01 -6.4594316186373 Down 0.473616431118743 19835726 604.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 318845 555.00 0.37 0.17 -1.12199052437861 Down 0.152522784308546 CG31609 CG31609 K06238|1|3e-10|63.9|gga:396548|collagen, type VI, alpha;K01289|2|4e-10|63.5|cel:F22E12.1|carboxypeptidase [EC:3.4.16.-];K08117|5|1e-08|58.9|oaa:100093419|amyloid beta (A4) precursor-like protein 2 - GO:0004866//endopeptidase inhibitor activity - 19835836 1580.00 0.05 0.03 -0.736965594166206 Down 0.0552767137762515 33511 2677.00 1.71 3.265 0.933086666660533 Up 0.414872539955092 CG17264 CG17264, isoform B - - - - 38290 636.00 15.115 14.325 -0.0774458399834401 Down 0.159126931713116 CG13807 CG13807 - - - - 46456 1663.40 59.605 63.74 0.0967656620417065 Up 0.245178972394664 CanB2 calcineurin B2, isoform B K06268|1|5e-93|341|dya:Dyak_GE19147|protein phosphatase 3, regulatory subunit GO:0008287//protein serine/threonine phosphatase complex;GO:0030136//clathrin-coated vesicle GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0004722//protein serine/threonine phosphatase activity GO:0014866//skeletal myofibril assembly;GO:0006464//cellular protein modification process;GO:0001505//regulation of neurotransmitter levels;GO:0022403;GO:0042993//positive regulation of transcription factor import into nucleus 44382 1168.00 0.01 0.04 2 Up 0.0694426099590543 Sr-CIII scavenger receptor class C, type III - GO:0044464//cell part - - 39570 1737.91 13.805 15.465 0.163815945501195 Up 0.271232333905693 D dichaete, isoform D K09267|1|3e-108|393|dwi:Dwil_GK17143|transcription factor SOX1/2/3/14/21 (SOX group B) GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003729//mRNA binding GO:0008298//intracellular mRNA localization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0002164//larval development;GO:0001736//establishment of planar polarity;GO:0040008//regulation of growth;GO:0009798//axis specification;GO:0007476//imaginal disc-derived wing morphogenesis 45668 2609.60 316.66 332.21 0.0691608612792695 Up 0.202714304583278 Vha68-1 vacuolar H[+] ATPase 68kD subunit 1, isoform B K02145|1|0.0|1226|dya:Dyak_GE11978|V-type H+-transporting ATPase subunit A [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport 36687 801.00 6.365 6.22 -0.0332459337707555 Down 0.06927750627394 CG11808 CG11808 - GO:0005681//spliceosomal complex - GO:0000377 19835513 628.00 1.065 0.4 -1.41278152533848 Down 0.299299960375116 37757 4284.53 25.795 27.72 0.10383581098454 Up 0.222130497952714 egl egalitarian, isoform C - GO:0000502//proteasome complex GO:0004527//exonuclease activity;GO:0004175//endopeptidase activity;GO:0005488//binding GO:0034641//cellular nitrogen compound metabolic process;GO:0006508//proteolysis 35789 653.25 1583.69 1792.185 0.17842960648421 Up 0.404702152952054 Obp44a Odorant-binding protein 44a, isoform B - - GO:0005488//binding GO:0051234//establishment of localization 32250 752.00 0.37 0.765 1.0479344770637 Up 0.221767269845463 CG2209 CG2209 - - - - 39855 944.00 117.11 72.115 -0.699492994585789 Down 0.683166028265751 Pros26 proteasome beta6 subunit K02732|1|5e-132|470|dme:Dmel_CG4097|20S proteasome subunit beta 6 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process 44027 9529.67 18.09 20.97 0.213134453475352 Up 0.353090740985339 sbb scribbler, isoform J K10847|1|3e-38|162|spu:582941|DNA-repair protein complementing XP-A cells GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0003712//transcription cofactor activity;GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007472//wing disc morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007472//wing disc morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007472//wing disc morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007472//wing disc morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007472//wing disc morphogenesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007626//locomotory behavior;GO:0006935//chemotaxis;GO:0008589//regulation of smoothened signaling pathway;GO:0046620//regulation of organ growth;GO:0007472//wing disc morphogenesis 31796 666.81 1.08 1.135 0.071660985127446 Up 0.0561022322018227 CG12111 CG12111, isoform B K06560|1|4e-12|70.9|nve:NEMVE_v1g238062|mannose receptor, C type - - - 31863 1675.88 275.475 447.485 0.699917926282681 Up 0.696704530445119 t tan, isoform B - GO:0044444//cytoplasmic part GO:0016787//hydrolase activity GO:0048066//developmental pigmentation;GO:0050953//sensory perception of light stimulus;GO:0030654;GO:0001692//histamine metabolic process;GO:0042417//dopamine metabolic process 36614 6145.53 12.185 13.66 0.16485123256675 Up 0.262481838594637 ttv tout-velu, isoform C K02366|1|0.0|1441|dme:Dmel_CG10117|glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225] GO:0005789//endoplasmic reticulum membrane GO:0015020//glucuronosyltransferase activity;GO:0005488//binding;GO:0008375//acetylglucosaminyltransferase activity GO:0007276//gamete generation;GO:0006024//glycosaminoglycan biosynthetic process;GO:0007224//smoothened signaling pathway;GO:0006041//glucosamine metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 2768959 330.00 4.885 6.14 0.329880093401794 Up 0.313531898031964 CG33255 CG33255 - - - - 34506 556.00 0.085 0.085 0 - 0.0382380134724607 CG12517 CG12517 - - - - 34657 929.00 1.265 1.77 0.484611975388687 Up 0.21443666622639 CG5435 CG5435, isoform B K00555|1|2e-09|62.8|dme:Dmel_CG6388|tRNA (guanine-N2-)-methyltransferase [EC:2.1.1.32] - - - 39915 530.00 5.72 5 -0.194087052116302 Down 0.207436269977546 CG14057 CG14057, isoform B K03537|1|2e-68|257|dpo:Dpse_GA12728|ribonuclease P subunit P14 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004549//tRNA-specific ribonuclease activity;GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process 40722 1721.46 8.01 10.525 0.393946085545048 Up 0.422566371681416 CG42675 CG42675, isoform G - - - - 34088 2171.63 7.13 2.975 -1.26101240824858 Down 0.591500462290318 CG7227 CG7227, isoform C K06259|1|1e-43|178|dre:436636|CD36 antigen;K13885|2|4e-42|173|mdo:100029588|scavenger receptor class B, member 1;K12384|4|1e-40|168|mmu:12492|lysosome membrane protein 2 GO:0016021//integral to membrane GO:0004888//transmembrane signaling receptor activity GO:0016108;GO:0007165//signal transduction;GO:0048102//autophagic cell death;GO:0006726//eye pigment biosynthetic process 42271 471.80 137.625 122.92 -0.163022891746131 Down 0.361478008189143 CG12269 CG12269, isoform B - - GO:0005496//steroid binding - 32202 7438.85 17.43 23.3 0.418757385415958 Up 0.524930656452252 CG43921 CG43921, isoform D K07365|1|6e-09|60.8|dre:393972|NCK adaptor protein - - - 45884 5524.00 43.195 14.905 -1.53506794880311 Down 0.743527935543521 kkv krotzkopf verkehrt, isoform D K00698|1|0.0|2954|dme:Dmel_CG2666|chitin synthase [EC:2.4.1.16] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0016331//morphogenesis of embryonic epithelium;GO:0040003//chitin-based cuticle development;GO:0035151//regulation of tube size, open tracheal system;GO:0006031//chitin biosynthetic process;GO:0016331//morphogenesis of embryonic epithelium;GO:0040003//chitin-based cuticle development;GO:0035151//regulation of tube size, open tracheal system;GO:0006031//chitin biosynthetic process;GO:0016331//morphogenesis of embryonic epithelium;GO:0040003//chitin-based cuticle development;GO:0035151//regulation of tube size, open tracheal system;GO:0006031//chitin biosynthetic process 31217 4152.32 11.56 12.15 0.0718149159924641 Up 0.136276581693303 CG2865 CG2865, isoform B - - - - 42817 7437.57 16.14 17.185 0.0905092730945168 Up 0.1816470743627 mbc myoblast city, isoform B K05727|1|0.0|3719|dme:Dmel_CG10379|dedicator of cytokinesis 3/4/5;K13708|3|0.0|1277|bta:537203|dedicator of cytokinesis 1 GO:0031252//cell leading edge GO:0032561//guanyl ribonucleotide binding;GO:0030695//GTPase regulator activity;GO:0019899//enzyme binding GO:0001700//embryonic development via the syncytial blastoderm;GO:0014706//striated muscle tissue development;GO:0032989;GO:0002164//larval development;GO:0000768//syncytium formation by plasma membrane fusion 33992 1290.00 1.325 0.99 -0.420491929370952 Down 0.171047417778365 Nuf2 Nuf2 K06636|1|4e-11|69.3|phu:Phum_PHUM470210|structural maintenance of chromosome 1;K10381|2|2e-09|63.5|oaa:100083608|desmoplakin;K10421|5|5e-09|62.4|rno:65201|CAP-Gly domain-containing linker protein 1 GO:0044427//chromosomal part - GO:0000087//M phase of mitotic cell cycle 19834854 363.00 1.88 2.05 0.124891247827809 Up 0.0922929599788667 39151 751.00 44.195 68.82 0.638944732486178 Up 0.658862765816933 Ilp3 Insulin-like peptide 3 - - - - 31496 5802.99 6.335 6.08 -0.0592732956972239 Down 0.0939439968300092 IntS6 integrator 6, isoform E K13143|1|0.0|1291|dme:Dmel_CG3125|integrator complex subunit 6 - - - 37036 2514.00 5.8 5.735 -0.0162594139991098 Down 0.0542200501915203 CG5033 CG5033 K01062|1|9e-09|62.8|smm:Smp_129340|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47];K10260|5|2e-08|61.6|dre:564991|F-box and WD-40 domain protein 7 - - - 41679 1613.00 55.325 43.735 -0.339143252195578 Down 0.531336679434685 Adgf-D adenosine deaminase-related growth factor D K01488|1|0.0|993|dme:Dmel_CG9621|adenosine deaminase [EC:3.5.4.4] - - - 38918 1340.00 0.985 2.125 1.10926721156869 Up 0.372374851406683 CG7366 CG7366 - - - - 35781 989.00 15.195 36.85 1.27806794446014 Up 0.721205917316075 CG18316 under-developed - - - - 43600 1635.00 0.34 0.605 0.831400396024255 Up 0.16497160216616 CG9737 CG9737 K01312|1|2e-53|210|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|8e-53|208|dme:Dmel_CG4920| [EC:3.4.21.-];K03993|5|1e-32|140|oaa:100079601|mannan-binding lectin serine protease 2 [EC:3.4.21.104] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006909//phagocytosis 50459 731.19 185.1 196.335 0.0850124850608758 Up 0.240093778893145 CG6115 CG6115, isoform B - GO:0043231//intracellular membrane-bounded organelle - - 12797883 848.41 0.245 0.515 1.07179068306801 Up 0.178906353189803 CG43449 CG43449, isoform B - - - - 53579 1471.00 14.845 15.71 0.0817060873075409 Up 0.163221503103949 Dip3 dorsal interacting protein 3 K09427|1|4e-06|53.1|dpo:Dpse_GA13983|Adh transcription factor 1 GO:0044451//nucleoplasm part GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0035114//imaginal disc-derived appendage morphogenesis;GO:0042480//negative regulation of eye photoreceptor cell development;GO:0010557//positive regulation of macromolecule biosynthetic process 37664 2230.00 4.54 4.225 -0.103740956121368 Down 0.117917051908599 Art7 arginine methyltransferase 7 K11438|1|0.0|1310|dme:Dmel_CG9882|protein arginine N-methyltransferase 7 [EC:2.1.1.-] GO:0044424//intracellular part GO:0016274//protein-arginine N-methyltransferase activity GO:0006479//protein methylation 36895 1597.00 10.975 4.805 -1.19161260364897 Down 0.633965130101704 CG6472 CG6472 K01046|1|8e-40|164|api:100163959|triacylglycerol lipase [EC:3.1.1.3] - - - 12798327 482.00 1.365 0.77 -0.825970600224951 Down 0.25937788931449 CG43237 CG43237 - - - - 318064 3798.00 1.41 1.97 0.482500467057582 Up 0.227215691454233 stg1 stargazin-like protein K04870|1|7e-11|70.5|dre:797409|voltage-dependent calcium channel gamma-5;K04872|4|2e-09|65.5|dre:100034540|voltage-dependent calcium channel gamma-7 GO:0031224//intrinsic to membrane - - 35111 3786.13 26.83 24.47 -0.132832953181132 Down 0.269317131158367 CG10413 CG10413, isoform B K10951|1|1e-67|258|cfa:481490|solute carrier family 12 member 2 GO:0044464//cell part - GO:0006810//transport 34800 923.00 1.18 2.39 1.01822375861891 Up 0.37987055871087 CG7916 CG7916 - - - - 33046 6238.00 11.175 13.525 0.275353762643497 Up 0.374587240787214 CG1695 CG1695 K13136|1|6e-27|123|nvi:100114269|gem associated protein 8 GO:0044464//cell part GO:0005099//Ras GTPase activator activity GO:0032318//regulation of Ras GTPase activity 32150 719.00 13.595 14.4 0.0829926603049145 Up 0.159424118346322 CG1840 CG1840, isoform B - GO:0042598;GO:0043231//intracellular membrane-bounded organelle - GO:0010259//multicellular organismal aging;GO:0019725//cellular homeostasis 42445 5681.64 4.485 4.565 0.0255068750649609 Up 0.0585787874785365 H hairless, isoform D K06064|1|0.0|1055|dme:Dmel_CG5460|hairless - GO:0005488//binding;GO:0016564//transcription repressor activity;GO:0005488//binding;GO:0016564//transcription repressor activity;GO:0005488//binding;GO:0016564//transcription repressor activity;GO:0005488//binding;GO:0016564//transcription repressor activity GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007423//sensory organ development;GO:0032989;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007350//blastoderm segmentation;GO:0001709//cell fate determination;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007423//sensory organ development;GO:0032989;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007350//blastoderm segmentation;GO:0001709//cell fate determination;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007423//sensory organ development;GO:0032989;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007350//blastoderm segmentation;GO:0001709//cell fate determination;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0032583;GO:0007423//sensory organ development;GO:0032989;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007350//blastoderm segmentation;GO:0001709//cell fate determination;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0060541//respiratory system development;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0008593//regulation of Notch signaling pathway 19836071 701.00 7.215 0.57 -3.66196557032646 Down 0.732366926429798 35045 3155.99 45.1 32.425 -0.476020859003682 Down 0.594076079778101 Dif Dorsal-related immunity factor, isoform D K09255|1|0.0|1105|dsi:Dsim_GD21872|Rel/ankyrin family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding GO:0007166//cell surface receptor signaling pathway;GO:0035168//larval lymph gland hemocyte differentiation;GO:0048666//neuron development;GO:0042742//defense response to bacterium;GO:0002783;GO:0001654//eye development;GO:0010551;GO:0033554//cellular response to stress;GO:0002682//regulation of immune system process;GO:0007435//salivary gland morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0035168//larval lymph gland hemocyte differentiation;GO:0048666//neuron development;GO:0042742//defense response to bacterium;GO:0002783;GO:0001654//eye development;GO:0010551;GO:0033554//cellular response to stress;GO:0002682//regulation of immune system process;GO:0007435//salivary gland morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0035168//larval lymph gland hemocyte differentiation;GO:0048666//neuron development;GO:0042742//defense response to bacterium;GO:0002783;GO:0001654//eye development;GO:0010551;GO:0033554//cellular response to stress;GO:0002682//regulation of immune system process;GO:0007435//salivary gland morphogenesis;GO:0035110;GO:0008595//anterior/posterior axis specification, embryo;GO:0007369//gastrulation;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007435//salivary gland morphogenesis;GO:0035168//larval lymph gland hemocyte differentiation;GO:0002682//regulation of immune system process;GO:0001708//cell fate specification;GO:0016043//cellular component organization;GO:0048863//stem cell differentiation;GO:0042742//defense response to bacterium;GO:0016477//cell migration;GO:0045596//negative regulation of cell differentiation;GO:0030707//ovarian follicle cell development;GO:0002783;GO:0010551;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048666//neuron development;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0001736//establishment of planar polarity;GO:0007476//imaginal disc-derived wing morphogenesis 14462912 252.00 3.465 4.57 0.399338812920856 Up 0.306795667679303 41160 3094.00 16.99 15.065 -0.173485179589758 Down 0.291176859067494 CG8301 CG8301 K09228|1|2e-57|224|ptr:455016|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 42165 2421.09 14.27 13.68 -0.0609171045898656 Down 0.130035662395985 CG7218 CG7218, isoform B - - - - 3771948 299.00 92.065 34.41 -1.41982490459641 Down 0.752377493065645 42014 442.00 20.08 22.155 0.141873057535174 Up 0.271562541275921 CG14903 CG14903 K04794|1|3e-33|139|xla:779309|peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] - - - 38464 3969.00 14.775 16.265 0.138612691976237 Up 0.248580108308017 CG14982 CG14982, isoform C - - - - 53569 3279.00 12.175 12.16 -0.00177854352611906 Down 0.0416061286487914 raps rapsynoid K09257|1|1e-14|82.4|dre:492655|nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2;K10366|3|1e-11|72.4|bfo:BRAFLDRAFT_125744|dystrophin GO:0044448//cell cortex part GO:0008047//enzyme activator activity;GO:0005488//binding GO:0001709//cell fate determination;GO:0023060;GO:0008105//asymmetric protein localization;GO:0051235;GO:0040001//establishment of mitotic spindle localization;GO:0051301//cell division;GO:0048699//generation of neurons 3772640 1245.00 3.645 3.175 -0.199162222667409 Down 0.169990754193634 CG33786 CG33786 K03019|1|9e-163|386|dpo:Dpse_GA17233|DNA-directed RNA polymerase III subunit C11 [EC:2.7.7.6] GO:0044451//nucleoplasm part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity GO:0010468//regulation of gene expression 19835941 761.00 0.11 0.065 -0.758991900496205 Down 0.0694426099590543 42622 3665.00 7.31 6.485 -0.172764831700738 Down 0.214271562541276 CG18596 CG18596 - - GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0010467//gene expression 37387 1918.00 28.13 24.905 -0.175674141642112 Down 0.336118082155594 cpa capping protein alpha K10364|1|2e-165|582|dsi:Dsim_GD11558|capping protein (actin filament) muscle Z-line, alpha - - - 41953 5379.00 0.67 0.77 0.200697350237129 Up 0.0821555937128517 CG10185 CG10185 K11127|1|4e-17|91.7|bfo:BRAFLDRAFT_128562|telomerase protein component 1 - - - 43051 1358.00 37.61 28.19 -0.415932828469885 Down 0.558975036322811 CG10513 CG10513 - - - - 32910 5498.00 14.445 15.85 0.133912636462154 Up 0.236362435609563 Ulp1 Ulp1 K08592|1|3e-52|207|tgu:100217880|sentrin-specific protease 1 [EC:3.4.22.-] GO:0019866//organelle inner membrane;GO:0005635//nuclear envelope GO:0019783//small conjugating protein-specific protease activity GO:0051604//protein maturation 42485 13992.83 0.74 1.425 0.945364743423154 Up 0.284539690925901 Dhc93AB dynein heavy chain at 93AB, isoform C K10408|1|0.0|2089|tad:TRIADDRAFT_23475|dynein heavy chain, axonemal GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559 GO:0007017//microtubule-based process 41434 3037.48 29.155 23.64 -0.302513287245619 Down 0.465790516444327 CG6959 CG6959, isoform C K06260|1|5e-12|73.9|dre:100148153|platelet glycoprotein V;K10168|2|7e-11|70.1|ssc:100144476|toll-like recepto 5;K13023|3|2e-09|65.5|ecb:100069043|carboxypeptidase N regulatory subunit - - - 42962 2443.86 7.375 5.425 -0.443019911804724 Down 0.397140404173821 Esp epidermal stripes and patches, isoform B K03321|1|4e-38|160|rno:64076|sulfate permease, SulP family;K04602|2|4e-35|150|gga:416011|cadherin EGF LAG seven-pass G-type receptor 3 (flamingo);K13962|3|3e-34|147|tgu:100223009|solute carrier family 26 (sulfate anion transporter), member 7 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport 12798252 1270.00 0.125 0.105 -0.251538766995964 Down 0.0524039096552635 CG43120 CG43120 - - - - 40931 3712.57 49.375 51.295 0.0550374572505255 Up 0.166094307224937 wtrw water witch, isoform D K04984|1|9e-34|146|hsa:8989|transient receptor potential cation channel subfamily A member 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005261//cation channel activity;GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0006810//transport;GO:0009415//response to water stimulus;GO:0006810//transport;GO:0009415//response to water stimulus;GO:0006810//transport;GO:0009415//response to water stimulus 19835972 395.00 0.01 0.125 3.64385618977472 Up 0.151697265882974 32954 1607.35 11.665 12.72 0.124912363300156 Up 0.206610751551975 CG14220 CG14220, isoform B - - - - 41659 729.00 0.165 0.185 0.165059246270496 Up 0.0510500594373266 CG14370 CG14370 - - - - 42523 3136.61 2.555 2.755 0.108729027633536 Up 0.0970479461101572 ETHR ETHR, isoform C K04284|1|5e-33|143|ssc:397372|growth hormone secretagogue receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0023060 19836164 1549.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 50124 486.00 0.175 0.76 2.11864449649862 Up 0.298342359001453 CG15458 CG15458 - GO:0030529//ribonucleoprotein complex - GO:0010467//gene expression 14462589 540.00 0.01 0.105 3.39231742277876 Up 0.13426231673491 37076 3360.00 20.165 22.795 0.176864003458889 Up 0.323339056927751 CG10915 CG10915, isoform B K10352|1|2e-08|61.6|dpe:Dper_GL10886|myosin heavy chain;K06106|5|4e-08|60.8|api:100168801|cortactin - - - 43724 3936.44 181.77 230.465 0.342433558299588 Up 0.563399815083873 CycG cyclin G, isoform F K04501|1|5e-62|239|dya:Dyak_GE10952|SMAD, mothers against DPP 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005694//chromosome;GO:0005694//chromosome;GO:0005694//chromosome;GO:0005694//chromosome GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 32670 2027.00 1.835 1.975 0.106072590221253 Up 0.0833443402456743 CG13005 CG13005 - - - - 8674007 244.00 2.095 1.525 -0.458141001249103 Down 0.227347774402325 Sfp33A4 seminal fluid protein 33A4 - - - - 31377 3785.00 16.245 16.59 0.0303181426263802 Up 0.0899154669132215 CG3626 CG3626 K00314|1|1e-107|392|gga:417146|sarcosine dehydrogenase [EC:1.5.99.1] GO:0044424//intracellular part GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process 38356 923.90 1.44 2.39 0.730941806538436 Up 0.317725531633866 CG2113 CG2113, isoform B - - - - 39444 1052.00 20.715 18.92 -0.130763731639812 Down 0.253169990754194 CG32109 CG32109 - - - - 43787 4335.48 236.97 256.01 0.111495736460724 Up 0.282327301545371 PMCA plasma membrane calcium ATPase, isoform S K05850|1|0.0|2118|dwi:Dwil_GK13713|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0046873//metal ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0046873//metal ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0046873//metal ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0046873//metal ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0032559;GO:0046873//metal ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0009206;GO:0070838//divalent metal ion transport;GO:0009206;GO:0070838//divalent metal ion transport;GO:0009206;GO:0070838//divalent metal ion transport;GO:0009206;GO:0070838//divalent metal ion transport;GO:0009206;GO:0070838//divalent metal ion transport 3885660 768.87 5.405 4.125 -0.389900498601472 Down 0.326971338000264 CG34051 CG34051, isoform B - - - - 36954 1782.00 4.865 5.735 0.237353681234713 Up 0.239565447100779 CG6550 CG6550 - - - - 12798510 632.00 2.17 3.65 0.7502014213229 Up 0.392517500990622 CG43342 CG43342 - - - - 47082 1721.46 28.56 30.2 0.0805525701833419 Up 0.189043719455818 Adf1 Adh transcription factor 1, isoform E K09427|1|5e-138|491|dme:Dmel_CG15845|Adh transcription factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding GO:0007613//memory;GO:0006355//regulation of transcription, DNA-dependent;GO:0007626//locomotory behavior;GO:0048812//neuron projection morphogenesis;GO:0008306//associative learning;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007613//memory;GO:0006355//regulation of transcription, DNA-dependent;GO:0007626//locomotory behavior;GO:0048812//neuron projection morphogenesis;GO:0008306//associative learning;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007613//memory;GO:0006355//regulation of transcription, DNA-dependent;GO:0007626//locomotory behavior;GO:0048812//neuron projection morphogenesis;GO:0008306//associative learning;GO:0010557//positive regulation of macromolecule biosynthetic process 5740195 758.92 3.7 5.475 0.565333693972224 Up 0.401862369568089 CG34232 CG34232, isoform C K13649|1|5e-06|50.8|bfo:BRAFLDRAFT_123559|folate receptor - - - 19834891 858.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 326182 1016.80 10.055 14.555 0.533601757817414 Up 0.5268788799366 CG31988 CG31988, isoform B K05760|1|4e-42|171|tca:658324|paxillin - GO:0046914//transition metal ion binding - 37416 821.00 2.245 3.155 0.490924560241402 Up 0.290219257693832 CG4286 CG4286 - - - - 43958 1825.00 8.1 9.03 0.156804079708871 Up 0.220380398890503 spag spaghetti K04460|1|9e-18|92.0|rno:65179|protein phosphatase 5 [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding GO:0009886//post-embryonic morphogenesis;GO:0007444//imaginal disc development 14462907 1712.00 11.79 13.46 0.191114691630555 Up 0.291275921278563 39652 1660.28 23.38 29.535 0.337150682091053 Up 0.496962092193898 Pex3 peroxin 3, isoform B K13336|1|0.0|639|dme:Dmel_CG6859|peroxin-3 GO:0031231//intrinsic to peroxisomal membrane - GO:0006996//organelle organization 3354976 895.00 71 110.495 0.638090158091183 Up 0.670056795667679 CG40467 CG40467 - GO:0005624//membrane fraction GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006810//transport;GO:0019725//cellular homeostasis 12797960 566.00 0.145 0.01 -3.85798099512757 Down 0.168967111345925 41317 1642.00 13.93 9.785 -0.509551501974449 Down 0.513406419231277 CG14696 CG14696 K01277|1|4e-06|53.1|tca:661730|dipeptidyl-peptidase III [EC:3.4.14.4] - - - 32973 2059.14 9.525 11.025 0.210987658064199 Up 0.290153216219786 Ssu72 Ssu72 ortholog, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0016791//phosphatase activity GO:0006396//RNA processing 4379850 7398.00 4.575 5.345 0.224418204549086 Up 0.222460705322943 CG34135 CG34135, isoform D K11291|1|1e-10|67.4|cqu:CpipJ_CPIJ008573|nuclear autoantigenic sperm protein - - - 33102 5469.00 2.335 1.17 -0.996914020126257 Down 0.37349755646546 CG1494 CG1494, isoform C K05643|1|1e-92|342|tad:TRIADDRAFT_49936|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 40947 1488.00 26.46 16.405 -0.689677467760257 Down 0.626436402060494 CG3223 CG3223 - - - - 8673989 2463.00 1.865 2.095 0.167774613444114 Up 0.113921542728834 42262 602.00 0.805 1.345 0.740545484442007 Up 0.241579712059173 CG14294 CG14294 - - - - 37469 908.00 4.36 5.4 0.308631272273904 Up 0.281732928278959 CG42365 CG42365 - - - - 36891 713.00 205.43 123.285 -0.736649602503415 Down 0.70030379078061 CG6426 CG6426 - - - - 39048 4671.24 76.71 80.285 0.0657158065530119 Up 0.191388191784441 Tequila tequila, isoform G K09624|1|8e-80|300|oaa:100077582|protease, serine, 12 (neurotrypsin, motopsin) [EC:3.4.21.-] GO:0044464//cell part;GO:0031224//intrinsic to membrane;GO:0016020//membrane;GO:0044464//cell part GO:0004175//endopeptidase activity;GO:0030247//polysaccharide binding;GO:0004888//transmembrane signaling receptor activity;GO:0004175//endopeptidase activity;GO:0030247//polysaccharide binding;GO:0004888//transmembrane signaling receptor activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004888//transmembrane signaling receptor activity GO:0007613//memory;GO:0019538//protein metabolic process;GO:0006022;GO:0007613//memory;GO:0019538//protein metabolic process;GO:0006022;GO:0034613//cellular protein localization;GO:0007613//memory;GO:0019538//protein metabolic process;GO:0007613//memory;GO:0019538//protein metabolic process 3772583 1108.86 7.8 8.91 0.191951307772311 Up 0.250891559899617 gdl gonadal, isoform C - - - GO:0007292//female gamete generation 34682 913.00 0.175 0.22 0.330148601692331 Up 0.0662726192048606 CG15484 CG15484 - GO:0043232 - GO:0007292//female gamete generation;GO:0003006//developmental process involved in reproduction;GO:0016458//gene silencing 38567 354.00 0.125 0.3 1.26303440583379 Up 0.147107383436798 CG13716 CG13716 - - - - 36236 1731.29 59.35 34.335 -0.789568066252426 Down 0.683793422269185 Drip drip, isoform G K09884|1|2e-117|423|dme:Dmel_CG9023|aquaporin rerated protein, invertebrate;K09866|2|2e-41|170|dre:445293|aquaporin-4;K09864|3|6e-40|165|xla:443817|aquaporin-1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005372//water transmembrane transporter activity;GO:0005372//water transmembrane transporter activity GO:0003008;GO:0042044//fluid transport;GO:0048878//chemical homeostasis;GO:0003008;GO:0042044//fluid transport;GO:0048878//chemical homeostasis 39785 564.00 96.35 92.86 -0.0532273856164218 Down 0.154504028529917 CG13067 CG13067 - - - - 34516 1256.41 14.125 14.175 0.00509786763967898 Up 0.0492999603751156 YL-1 YL-1, isoform B K11664|1|1e-158|559|dme:Dmel_CG4621|vacuolar protein sorting-associated protein 72 GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding;GO:0004468//lysine N-acetyltransferase activity;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0016570//histone modification;GO:0034728//nucleosome organization 59137 1179.00 0.01 0.04 2 Up 0.0694426099590543 CG18735 CG18735 K01312|1|7e-49|194|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K08670|2|6e-48|191|xla:394363|suppressor of tumorigenicity protein 14 [EC:3.4.21.109];K01320|3|2e-46|186|dre:100038778|coagulation factor VII [EC:3.4.21.21];K09638|4|2e-46|186|gga:418421|transmembrane protease, serine 7 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19834778 1154.00 0.01 0.04 2 Up 0.0694426099590543 38526 2222.00 45.43 50.99 0.166569032571817 Up 0.352001056663585 CG1316 CG1316 K13207|1|4e-13|77.0|tad:TRIADDRAFT_60275|CUG-BP- and ETR3-like factor;K13208|2|5e-13|76.6|hmg:100210863|ELAV like protein 2/3/4 - GO:0005488//binding - 38531 2690.00 0.065 0.1 0.62148837674627 Up 0.0622440892880729 dyl dusky-like, isoform C - GO:0044448//cell cortex part;GO:0005884//actin filament;GO:0044448//cell cortex part;GO:0005884//actin filament;GO:0044448//cell cortex part;GO:0005884//actin filament - GO:0008360//regulation of cell shape;GO:0031589//cell-substrate adhesion;GO:0030036//actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0031589//cell-substrate adhesion;GO:0030036//actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0031589//cell-substrate adhesion;GO:0030036//actin cytoskeleton organization 318271 749.00 0.06 0.38 2.66296501272243 Up 0.226687359661868 CG32971 CG32971, isoform C - GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0016251//general RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent;GO:0006355//regulation of transcription, DNA-dependent 41824 1605.80 677.945 525 -0.368850813052144 Down 0.589222031435742 Mf myofilin, isoform Q - GO:0030017//sarcomere;GO:0030017//sarcomere;GO:0030017//sarcomere;GO:0030017//sarcomere;GO:0030017//sarcomere - - 34965 1126.00 37 38.32 0.0505722903325056 Up 0.142814687623828 CG5861 CG5861 - - - - 34628 1035.00 1.4 0.225 -2.63742992061529 Down 0.428146876238278 CG14947 CG14947 - - - - 246454 1130.00 3.605 3.68 0.0297065068161901 Up 0.0565975432571655 CG30096 CG30096 - - - - 12798551 361.00 1.19 1.61 0.436099114806673 Up 0.192444855369172 CG43145 CG43145 - - - - 41789 1973.00 2.4 2.95 0.297680548640685 Up 0.204926693963809 CG14855 CG14855 K08202|1|1e-41|171|aag:AaeL_AAEL012443|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 - - - 246448 999.00 1.955 2.14 0.130442189093795 Up 0.0994914806498481 CG30090 CG30090 K01312|1|3e-33|142|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01344|2|4e-31|135|ecb:100051306|protein C (activated) [EC:3.4.21.69];K01362|5|1e-28|127|dme:Dmel_CG4920| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35738 5902.57 15.125 20.38 0.430218909116495 Up 0.518227446836613 Dgk diacyl glycerol kinase, isoform J K00901|1|0.0|786|dme:Dmel_CG34361|diacylglycerol kinase [EC:2.7.1.107] - GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0046914//transition metal ion binding;GO:0016301//kinase activity GO:0046488//phosphatidylinositol metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006796//phosphate-containing compound metabolic process 318094 1366.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 TwdlX TweedleX - - - - 19834825 1324.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 39555 2699.58 12.495 11.395 -0.132949976821407 Down 0.218630299828292 CG6650 CG6650, isoform C K08074|1|0.0|801|dpo:Dpse_GA19752|ADP-dependent glucokinase [EC:2.7.1.147] - GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0044238//primary metabolic process 33969 6310.03 39.015 4.93 -2.98436934828624 Down 0.79854048342359 CG18304 CG18304, isoform D K10352|1|5e-27|124|cin:100176037|myosin heavy chain - - - 41154 2711.99 2.99 4.06 0.441334242987071 Up 0.307357020208691 CG16789 CG16789, isoform B K00665|1|2e-173|610|tca:658978|fatty acid synthase, animal type [EC:2.3.1.85];K13254|2|3e-14|80.9|gga:421481|spastin [EC:3.6.4.3] - GO:0016462//pyrophosphatase activity;GO:0032559 - 19835452 334.00 0.395 0.445 0.171952682789295 Up 0.0647866860388324 37294 2790.00 32.225 31.82 -0.0182465229179657 Down 0.0807026812838463 CG10444 CG10444 K03307|1|1e-116|421|ptr:467108|solute:Na+ symporter, SSS family - - - 318138 548.00 0.745 0.585 -0.348803800878757 Down 0.113657376832651 CG32643 CG32643 - - - - 40644 1133.21 317.215 374.595 0.239870650265707 Up 0.473385285959583 7B2 7B2, isoform B - GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016023//cytoplasmic membrane-bounded vesicle GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0030162//regulation of proteolysis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030162//regulation of proteolysis;GO:0007186//G-protein coupled receptor signaling pathway 43830 1262.79 72.41 74.365 0.0384348236435307 Up 0.131422533350944 CG11076 CG11076, isoform E - - - - 42921 2622.00 0.19 0.435 1.19501598240514 Up 0.16890106987188 CG13617 CG13617, isoform B K14000|1|1e-07|58.9|xla:444366|ribosome-binding protein 1;K10386|2|7e-07|56.2|hsa:5493|periplakin;K04574|3|2e-06|54.7|ptr:458741|neurofilament heavy polypeptide;K10352|4|3e-06|54.3|xla:399266|myosin heavy chain;K11498|5|3e-06|54.3|mdo:100013897|centromeric protein E GO:0044464//cell part GO:0046914//transition metal ion binding - 34993 2449.98 26.21 28.6 0.125897793337334 Up 0.27004358737287 grp grapes, isoform F K02216|1|0.0|766|dme:Dmel_CG17161|serine/threonine-protein kinase Chk1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0009628//response to abiotic stimulus;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0031570;GO:0051297//centrosome organization;GO:0006508//proteolysis;GO:0007143//female meiosis;GO:0007051//spindle organization;GO:0048513//organ development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0009628//response to abiotic stimulus;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0031570;GO:0051297//centrosome organization;GO:0006508//proteolysis;GO:0007143//female meiosis;GO:0007051//spindle organization;GO:0048513//organ development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0009628//response to abiotic stimulus;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0031570;GO:0051297//centrosome organization;GO:0006508//proteolysis;GO:0007143//female meiosis;GO:0007051//spindle organization;GO:0048513//organ development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0009628//response to abiotic stimulus;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0031570;GO:0051297//centrosome organization;GO:0006508//proteolysis;GO:0007143//female meiosis;GO:0007051//spindle organization;GO:0048513//organ development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process 31473 1931.29 5.505 4.85 -0.182757816489879 Down 0.195845991282525 RhoGAP5A Rho GTPase activating protein at 5A, isoform B K02649|1|9e-24|112|bfo:BRAFLDRAFT_91712|phosphoinositide-3-kinase, regulatory subunit;K10360|2|6e-20|99.4|cin:100177964|myosin IX;K08878|3|1e-18|94.7|dre:568320|breakpoint cluster region protein [EC:2.7.11.1] - - - 32229 2764.38 4.84 5.31 0.133704813529559 Up 0.153711530841368 CG12717 CG12717, isoform B K08596|1|1e-50|202|cfa:487955|sentrin-specific protease 7 [EC:3.4.22.-] - GO:0070011//peptidase activity, acting on L-amino acid peptides - 36205 772.68 33.37 32.655 -0.0312477782729567 Down 0.102496367718927 CG42336 CG42336, isoform F - - - - 19834893 299.00 9.69 1.58 -2.61657210723798 Down 0.717474574032492 19835457 228.00 15.64 7.22 -1.11516977042018 Down 0.65721172896579 43162 3682.30 28.415 29.78 0.0676910385307703 Up 0.171047417778365 gro groucho, isoform J K04497|1|0.0|1260|dme:Dmel_CG8384|groucho GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0016055//Wnt receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008589//regulation of smoothened signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:0003006//developmental process involved in reproduction 41460 1796.52 5.33 6.035 0.179218237995846 Up 0.201888786157707 CG3313 CG3313, isoform B K11803|1|0.0|900|dme:Dmel_CG3313|WD repeat-containing protein 40A - - - 14462354 559.00 0.54 1.875 1.79585928321977 Up 0.429203539823009 43681 2392.49 9.955 8.11 -0.29571940150323 Down 0.354477611940299 CG15556 CG15556, isoform C K12839|1|2e-50|201|dmo:Dmoj_GI23624|survival of motor neuron-related-splicing factor 30;K08451|2|3e-15|84.3|tgu:100229851|G protein-coupled receptor 64;K08455|4|4e-15|84.0|cfa:492163|G protein-coupled receptor 112 GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway 34809 2415.17 11.37 5.11 -1.15383705795463 Down 0.632941487253995 CG16886 CG16886, isoform B - - - - 33082 2676.00 19.435 17.615 -0.141852632844234 Down 0.263109232598072 CG1518 CG1518, isoform C K07151|1|0.0|1355|dme:Dmel_CG1518|dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.1.119] GO:0044464//cell part GO:0016758//transferase activity, transferring hexosyl groups GO:0006464//cellular protein modification process 36323 386.00 0.225 0.375 0.736965594166206 Up 0.121912561088363 CG13171 CG13171 - - - - 34948 948.00 0.66 0.28 -1.23703919730085 Down 0.220446440364549 CG4891 CG4891 - - - - 42496 5353.00 28.29 31.905 0.173490357285576 Up 0.333608506141857 RhoGAP93B Rho GTPase activating protein at 93B K07526|1|2e-13|79.7|cbr:CBG06126|SLIT-ROBO Rho GTPase activating protein;K10360|4|2e-11|72.8|gga:420135|myosin IX;K10359|5|2e-11|72.4|ecb:100069275|myosin VII GO:0043232 GO:0005488//binding GO:0006935//chemotaxis;GO:0023060 42816 5403.60 10.595 11.77 0.151730732666274 Up 0.23609826971338 Nup98-96 nucleoporin 98-96kD, isoform D - GO:0005635//nuclear envelope - GO:0051234//establishment of localization 39329 4988.78 16.86 14.315 -0.236076865942729 Down 0.360091137234183 Pi3K68D phosphotidylinositol 3 kinase 68D, isoform E K00923|1|0.0|3475|dme:Dmel_CG11621|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0005543//phospholipid binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0005543//phospholipid binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0005543//phospholipid binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0005543//phospholipid binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035004//phosphatidylinositol 3-kinase activity GO:0006909//phagocytosis;GO:0019932//second-messenger-mediated signaling;GO:0033554//cellular response to stress;GO:0030384;GO:0006909//phagocytosis;GO:0019932//second-messenger-mediated signaling;GO:0033554//cellular response to stress;GO:0030384;GO:0006909//phagocytosis;GO:0019932//second-messenger-mediated signaling;GO:0033554//cellular response to stress;GO:0030384;GO:0006909//phagocytosis;GO:0019932//second-messenger-mediated signaling;GO:0033554//cellular response to stress;GO:0030384 41602 3227.16 65.78 65.03 -0.0165435843951453 Down 0.0867784968960507 CtBP C-terminal binding protein, isoform J K04496|1|0.0|743|dsi:Dsim_GD18873|C-terminal binding protein - - - 43579 1176.36 14.595 12.775 -0.192150919677284 Down 0.30015849953771 CG7950 CG7950, isoform B - - GO:0004518//nuclease activity;GO:0004518//nuclease activity GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process 38370 3953.00 53.9 16.52 -1.70607158622042 Down 0.75845330867785 Cht7 Cht7 K01183|1|0.0|1872|dme:Dmel_CG1869|chitinase [EC:3.2.1.14] GO:0031224//intrinsic to membrane GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding GO:0006026 42352 1705.00 0.14 0.175 0.321928094887362 Up 0.0606260731739532 CG11659 CG11659 K01904|1|6e-43|175|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12] - - - 43196 2888.46 70.82 68.735 -0.0431119343747946 Down 0.131917844406287 CG5455 CG5455, isoform B - - - - 43036 1076.77 15.335 34.76 1.18059991554738 Up 0.709582617884031 to takeout, isoform B K12347|1|5e-11|68.6|dan:Dana_GF18523|natural resistance-associated macrophage protein - - GO:0042594//response to starvation;GO:0048511//rhythmic process;GO:0007631//feeding behavior;GO:0007619//courtship behavior 42710 2203.13 11.98 19.29 0.687225235260318 Up 0.601637828556333 Nha2 Na[+]/H[+] hydrogen antiporter 2, isoform B - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0042995//cell projection GO:0015298//solute:cation antiporter activity GO:0006811//ion transport 43168 814.00 8.94 9.915 0.14933794104553 Up 0.219191652357681 CG14550 CG14550 K03861|1|1e-75|282|dme:Dmel_CG14550|phosphatidylinositol glycan, class P - - - 32621 1628.00 0.1 0.235 1.23266075679027 Up 0.128054418174614 CG9903 CG9903 K03453|1|2e-13|77.4|isc:IscW_ISCW015359|bile acid:Na+ symporter, BASS family GO:0044464//cell part GO:0005343//organic acid:sodium symporter activity GO:0030001//metal ion transport 37994 2303.62 54.2 49.55 -0.129407794167384 Down 0.295073306036191 CG2765 CG2765, isoform F - - - - 42216 3009.18 57.84 40.815 -0.502968094980283 Down 0.613129045040285 Vha100-2 vacuolar H[+] ATPase 100kD subunit 2, isoform B K02154|1|0.0|1665|dme:Dmel_CG18617|V-type H+-transporting ATPase subunit I [EC:3.6.3.14] GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process;GO:0006754//ATP biosynthetic process 33211 4639.95 56.805 62.75 0.143597537119921 Up 0.315348038568221 alpha-Adaptin adaptor protein complex 2, alpha subunit, isoform B K11824|1|0.0|1746|dya:Dyak_GE16139|AP-2 complex subunit alpha GO:0030119//AP-type membrane coat adaptor complex;GO:0030128//clathrin coat of endocytic vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030128//clathrin coat of endocytic vesicle GO:0005488//binding;GO:0022892;GO:0005488//binding;GO:0022892 GO:0006901//vesicle coating;GO:0051301//cell division;GO:0001505//regulation of neurotransmitter levels;GO:0030100//regulation of endocytosis;GO:0015031//protein transport;GO:0006901//vesicle coating;GO:0051301//cell division;GO:0001505//regulation of neurotransmitter levels;GO:0030100//regulation of endocytosis;GO:0015031//protein transport 38369 4313.37 39.515 52.17 0.400820025197138 Up 0.563630960243033 CG11486 CG11486, isoform R K12572|1|0.0|1412|dsi:Dsim_GD13726|PAB-dependent poly(A)-specific ribonuclease subunit 3 - GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559;GO:0016301//kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 43687 1028.00 0.04 0.01 -2 Down 0.0694426099590543 bnk bottleneck - GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0007275//multicellular organismal development;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis 39118 5762.00 12.035 9.855 -0.288308365431011 Down 0.369931316866992 LanB2 laminin B2, isoform B K05635|1|0.0|3332|dme:Dmel_CG3322|laminin, gamma 1 GO:0005578//proteinaceous extracellular matrix - GO:0009987//cellular process;GO:0009653//anatomical structure morphogenesis 34194 1979.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 CG9287 CG9287 K03927|1|2e-41|170|bta:505928|carboxylesterase type B [EC:3.1.1.1];K01063|2|4e-39|162|dme:Dmel_CG8425|juvenile-hormone esterase [EC:3.1.1.59] - - - 47746 626.00 13.175 16.425 0.318090408685115 Up 0.430425307092854 Lk leucokinin - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0019932//second-messenger-mediated signaling;GO:0046903//secretion 34767 7257.36 25.76 24.84 -0.0524674198941355 Down 0.134163254523841 B4 B4, isoform C - - - GO:0048511//rhythmic process;GO:0048511//rhythmic process 3772464 2115.00 1.33 1.015 -0.389946518316013 Down 0.161438383304715 CG33914 CG33914, isoform C K12602|1|4e-09|60.5|dpo:Dpse_GA17766|WD repeat-containing protein 61 - - - 42416 268.00 1.36 0.97 -0.487549999063212 Down 0.18894465724475 MtnC metallothionein C - - GO:0046914//transition metal ion binding GO:0030003//cellular cation homeostasis 12798172 1090.00 0.28 0.32 0.192645077942396 Up 0.0609232598071589 CG43245 CG43245, isoform B - - - - 10178825 765.00 1.285 0.805 -0.674707671079261 Down 0.220314357416458 CG42650 CG42650 - - - - 41668 1515.00 0.155 0.46 1.56936564567014 Up 0.200832122572976 Rbp4 RNA-binding protein 4 K12741|1|1e-38|161|cqu:CpipJ_CPIJ001612|heterogeneous nuclear ribonucleoprotein A1/A3 - - - 45962 395.75 26.005 31.015 0.254177086975554 Up 0.421113459252411 msopa male-specific opa containing gene, isoform B - - - - 19835641 5913.00 13.92 15.14 0.121205994137003 Up 0.217771760665698 32725 4049.81 2.575 2.555 -0.0112491411329596 Down 0.0432901862369568 CG8611 CG8611, isoform C K13179|1|3e-63|244|cin:100175182|ATP-dependent RNA helicase DDX18 [EC:3.6.4.13] - GO:0032559;GO:0042623//ATPase activity, coupled;GO:0032559;GO:0042623//ATPase activity, coupled - 34381 1834.00 0.125 0.08 -0.643856189774725 Down 0.0752542596750759 CG13138 CG13138, isoform C - - - - 19835588 4809.00 11.605 12.58 0.116385399534807 Up 0.200633998150839 38794 715.50 668.89 704.67 0.0751788184190866 Up 0.225465592392022 RpL18 ribosomal protein L18, isoform C K02883|1|1e-103|375|dme:Dmel_CG8615|large subunit ribosomal protein L18e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 31975 1179.00 0.07 0.05 -0.485426827170242 Down 0.0549134856690001 Or9a odorant receptor 9a K08471|1|0.0|751|dme:Dmel_CG15302|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 8674073 1023.00 15.495 13.605 -0.187665798336537 Down 0.303460573239995 CG42554 CG42554 - - - - 40989 953.00 20.295 10.595 -0.937740752325524 Down 0.654140800422665 Ctr1B copper transporter 1B - GO:0031224//intrinsic to membrane GO:0005375//copper ion transmembrane transporter activity GO:0010035//response to inorganic substance;GO:0000041//transition metal ion transport 38601 2248.00 4.185 7.575 0.85601826580997 Up 0.534143442081627 CG4611 CG4611 - - - - 3772692 2688.45 0.97 1.63 0.74881531204395 Up 0.268458591995773 Menl-2 malic enzyme like-2, isoform E K00029|1|0.0|1059|dse:Dsec_GM20057|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process 40603 603.00 2.26 2.385 0.0776664935903237 Up 0.0739664509311848 CG14658 CG14658 - - - - 44013 31770.34 14.615 13.395 -0.125755247963674 Down 0.226819442609959 sls sallimus, isoform Z K12567|1|0.0|783|ecb:100053844|titin [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0031674//I band GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0031032//actomyosin structure organization;GO:0000070//mitotic sister chromatid segregation;GO:0000768//syncytium formation by plasma membrane fusion;GO:0048513//organ development;GO:0014706//striated muscle tissue development 33224 2065.77 43.925 34.62 -0.3434365615291 Down 0.521925769383173 cbt cabut, isoform C K13943|1|4e-163|575|dsi:Dsim_GD22954|cabut - GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0030528//transcription regulator activity;GO:0005488//binding GO:0000165//MAPK cascade;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009887//organ morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0048102//autophagic cell death;GO:0000165//MAPK cascade;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009887//organ morphogenesis;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001738//morphogenesis of a polarized epithelium;GO:0048102//autophagic cell death 32328 4353.64 8.955 8.915 -0.00645863436096646 Down 0.0472856954167217 CG9940 CG9940, isoform C K01950|1|0.0|1511|dme:Dmel_CG9940|NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] - GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016787//hydrolase activity;GO:0032559;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016787//hydrolase activity;GO:0032559 GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process 10178851 621.00 0.07 0.075 0.0995356735509144 Up 0.0433232069739797 CG42857 CG42857 - - - - 31729 5184.75 20.475 24.275 0.245607843778183 Up 0.401267996301677 CG2258 CG2258, isoform D - - - - 35611 1418.44 16.88 13.45 -0.327708731263199 Down 0.440034341566504 CG30159 CG30159, isoform C - - - - 34144 848.01 81.205 64.45 -0.333388201990074 Down 0.538171971998415 CG14275 CG14275, isoform B - - - - 41047 1562.00 0.59 1 0.761213140412884 Up 0.20991282525426 CG8236 CG8236 - - - - 5740664 515.06 95.84 108.645 0.180921967895698 Up 0.386672830537578 CG40228 CG40228, isoform F - GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding GO:0010468//regulation of gene expression 30973 2110.00 20.44 18.83 -0.118362196323393 Down 0.23471139875842 cin cinnamon K03750|1|0.0|1193|dme:Dmel_CG2945|molybdopterin biosynthesis protein MoeA - - - 37174 953.00 267.855 311.365 0.217154555850052 Up 0.450733060361907 CG15098 CG15098 - - - - 31600 851.00 23.415 21.135 -0.147798925668272 Down 0.287445515783912 CG3224 CG3224 - - - - 5740420 6026.00 72.78 96.815 0.411688537116785 Up 0.589585259542993 19834885 718.00 1.105 1.54 0.47888398130347 Up 0.199907541936336 40696 1080.00 5.255 3.925 -0.420998110183189 Down 0.337504953110553 MED27 mediator complex subunit 27 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 32825 1028.56 15.325 5.795 -1.40300650757167 Down 0.683562277110025 CG42323 CG42323, isoform E - - - - 41123 2767.00 10.24 12.05 0.234817431117324 Up 0.320169066173557 CG8135 CG8135 - GO:0031224//intrinsic to membrane - - 31950 677.90 437.91 424.935 -0.0433922182804626 Down 0.13924844802536 l(1)G0230 lethal (1) G0230, isoform C K02134|1|4e-62|234|dsi:Dsim_GD24697|F-type H+-transporting ATPase subunit delta [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport 43934 1313.00 0.645 0.585 -0.14086253583985 Down 0.0661405362567692 gom gomdanji - - GO:0046872//metal ion binding GO:0019932//second-messenger-mediated signaling;GO:0007611//learning or memory 43984 2049.00 0.975 1.585 0.701008716389797 Up 0.252575617487782 Sdic1 Sperm-specific dynein intermediate chain 1, isoform C K10415|1|0.0|992|dme:Dmel_CG9580|dynein intermediate chain, cytosolic GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0045502//dynein binding GO:0051640//organelle localization;GO:0046530//photoreceptor cell differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0003006//developmental process involved in reproduction;GO:0010970//microtubule-based transport 3772719 2245.00 2.145 2.045 -0.0688768045577966 Down 0.0677255316338661 CG33964 CG33964 K10903|1|4e-08|60.5|bfo:BRAFLDRAFT_84669|HUS1 checkpoint protein - - - 5740867 693.00 0.175 0.01 -4.12928301694497 Down 0.187062475234447 CG34428 CG34428 - - - - 34368 769.00 130.97 144.72 0.144027927322853 Up 0.331825386342623 CG5676 CG5676 - - - - 39564 3753.00 6.55 4.44 -0.560935230074707 Down 0.42864218729362 btl breathless, isoform B K05093|1|0.0|1968|dme:Dmel_CG32134|fibroblast growth factor receptor 2 [EC:2.7.10.1];K13338|2|0.0|1152|dmo:Dmoj_GI13761|peroxin-1;K05094|5|2e-169|597|dme:Dmel_CG7223|fibroblast growth factor receptor 3 [EC:2.7.10.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032559;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0035051//cardiocyte differentiation;GO:0008354//germ cell migration;GO:0007417//central nervous system development;GO:0007444//imaginal disc development;GO:0002164//larval development;GO:0048333//mesodermal cell differentiation;GO:0048534;GO:0030035//microspike assembly;GO:0007517//muscle organ development;GO:0045137//development of primary sexual characteristics;GO:0001708//cell fate specification;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030308//negative regulation of cell growth;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0060446//branching involved in open tracheal system development;GO:0007431//salivary gland development;GO:0007509//mesoderm migration involved in gastrulation;GO:0035051//cardiocyte differentiation;GO:0008354//germ cell migration;GO:0007417//central nervous system development;GO:0007444//imaginal disc development;GO:0002164//larval development;GO:0048333//mesodermal cell differentiation;GO:0048534;GO:0030035//microspike assembly;GO:0007517//muscle organ development;GO:0045137//development of primary sexual characteristics;GO:0001708//cell fate specification;GO:0055002//striated muscle cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030308//negative regulation of cell growth;GO:0001709//cell fate determination;GO:0006464//cellular protein modification process;GO:0060446//branching involved in open tracheal system development;GO:0007431//salivary gland development;GO:0007509//mesoderm migration involved in gastrulation 38885 1663.00 39.985 39.725 -0.00941166832101009 Down 0.0628714832915071 RNaseX25 ribonuclease X25 K01172|1|2e-131|469|dpo:Dpse_GA20886| [EC:3.1.27.-] - GO:0016892;GO:0003676//nucleic acid binding GO:0016070//RNA metabolic process 3772213 1588.62 6.46 5.105 -0.339623203816123 Down 0.324891031567825 Tim9b translocase of inner membrane 9b, isoform D K10836|1|3e-46|183|dme:Dmel_CG17767|mitochondrial protein-transporting ATPase [EC:3.6.3.51] GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity;GO:0043169//cation binding;GO:0008320//protein transmembrane transporter activity GO:0006612//protein targeting to membrane;GO:0006612//protein targeting to membrane 34529 757.91 9.015 7.695 -0.228406165104131 Down 0.285893541143838 dUTPase deoxyuridine triphosphatase, isoform D K01520|1|4e-85|313|dme:Dmel_CG4584|dUTP pyrophosphatase [EC:3.6.1.23] - GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0047429//nucleoside-triphosphate diphosphatase activity GO:0009211;GO:0009211 31269 1550.64 19.93 21.82 0.130709391484549 Up 0.256538105930524 Syx4 syntaxin 4, isoform B K08486|1|4e-146|518|dme:Dmel_CG2715|syntaxin 1B/2/3 - - - 40316 3727.00 0.375 0.435 0.214124805352847 Up 0.0691124025888258 CG10588 CG10588, isoform B K01411|1|0.0|967|dan:Dana_GF19439|nardilysin [EC:3.4.24.61] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 41864 1641.00 70.46 60.825 -0.212140059669172 Down 0.415565975432572 Surf4 surfeit 4 - - - - 32075 799.00 5.745 5.16 -0.154935827222859 Down 0.175868445383701 CG1738 CG1738 - - - - 39373 600.00 1.14 0.975 -0.225559700415131 Down 0.104444591203276 CG17154 CG17154 - - - - 33844 1813.14 5.51 5.655 0.0374747054186627 Up 0.0709285431250826 CG9109 CG9109, isoform C K13675|1|0.0|1006|dse:Dsec_GM17972|UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-] GO:0044464//cell part GO:0016740//transferase activity - 32140 1110.42 42.225 40.68 -0.053777743831248 Down 0.145192180689473 p24-1 p24-related-1, isoform B K05409|1|1e-43|177|ptr:471605|TRIF-related adaptor molecule;K01529|3|5e-17|88.6|mcc:709884| [EC:3.6.1.-] GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane - GO:0048193//Golgi vesicle transport 33579 1484.00 0.555 0.39 -0.509013647487858 Down 0.123002245410118 Che-13 Che-13 ortholog K04638|1|0.0|736|dme:Dmel_CG8853|estrogen-related receptor beta like 1 - - GO:0010927 2768668 1284.00 4.745 4.64 -0.0322832818935372 Down 0.0618808611808216 CG33331 CG33331 - - - - 19835527 515.00 0.085 0.36 2.08246216019197 Up 0.197232862237485 40594 2137.00 4.21 4.04 -0.0594649403146014 Down 0.0806696605468234 CG14655 CG14655 K10590|1|3e-75|283|ame:409382|E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19];K09228|4|2e-35|151|mmu:319615|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 37680 983.78 0.71 0.79 0.154033628672421 Up 0.0742636375643904 CG13539 CG13539, isoform B - - - - 33583 2347.00 1.22 1.035 -0.237250380063561 Down 0.111114780081891 odd odd skipped K09215|1|1e-156|553|dme:Dmel_CG3851|odd-skipped GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006355//regulation of transcription, DNA-dependent;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0007365//periodic partitioning 35153 1573.33 27.36 22.57 -0.277661811694062 Down 0.440496631884824 CG10623 CG10623, isoform C K00547|1|1e-95|350|dpo:Dpse_GA10443|homocysteine S-methyltransferase [EC:2.1.1.10] - GO:0008172 - 39378 1908.00 0.025 0.025 0 - 0.0382380134724607 Ir68b ionotropic receptor 68b - GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 37771 1035.00 0.01 0.045 2.16992500144231 Up 0.0694426099590543 CG4763 CG4763 - - - - 32573 1377.53 102.46 88.03 -0.218993624002939 Down 0.436071853123762 Nipsnap nipsnap, isoform F - - - - 36347 787.27 6.045 3.935 -0.619378703741637 Down 0.435642583542465 CG8501 CG8501, isoform B - - - - 36460 1280.00 22 21.345 -0.0436053611643834 Down 0.114482895258222 Fsn Fsn, isoform B K10319|1|2e-153|541|dme:Dmel_CG4643|F-box protein 45 GO:0044459//plasma membrane part;GO:0045202//synapse;GO:0044459//plasma membrane part;GO:0045202//synapse - GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0008582//regulation of synaptic growth at neuromuscular junction 5740497 1590.00 2.38 3.125 0.392894616241506 Up 0.25452384097213 inaF-C inaF-C - GO:0044464//cell part GO:0016247//channel regulator activity;GO:0005488//binding GO:0016057//regulation of membrane potential in photoreceptor cell 32208 2509.00 22.725 24.9 0.131865447873974 Up 0.264463082816008 CG1824 CG1824 K05655|1|4e-176|618|dre:548340|ATP-binding cassette, subfamily B (MDR/TAP), member 8 GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0032559 GO:0006810//transport 19836198 1099.00 0.08 0.05 -0.678071905112638 Down 0.06244221371021 19835918 662.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 41498 3864.00 13.72 13.72 0 - 0.0382380134724607 MBD-R2 MBD-R2 K06230|1|3e-32|141|dwi:Dwil_GK13666|zinc finger protein GLI;K06101|2|3e-07|58.2|spu:579712|histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43] - - - 33155 1880.00 0.385 0.38 -0.0188590272513159 Down 0.0413749834896315 CG11023 CG11023, isoform D K08592|1|3e-53|209|gga:426185|sentrin-specific protease 1 [EC:3.4.22.-] GO:0019866//organelle inner membrane;GO:0005635//nuclear envelope;GO:0019866//organelle inner membrane;GO:0005635//nuclear envelope GO:0019783//small conjugating protein-specific protease activity;GO:0019783//small conjugating protein-specific protease activity GO:0051604//protein maturation;GO:0051604//protein maturation 32679 729.00 36.995 38.77 0.0676104363108931 Up 0.178444062871483 CG9099 CG9099, isoform B - - - - 42001 2274.00 1.47 1.91 0.377756483199384 Up 0.192246730947035 Gyc-89Da guanylyl cyclase at 89Da, isoform C K01769|1|0.0|1356|dme:Dmel_CG14885|guanylate cyclase, other [EC:4.6.1.2] - - - 36210 1893.00 6.655 6.365 -0.0642781520105339 Down 0.100184916127328 CG7745 CG7745 - - - - 42454 1510.00 1.22 1.455 0.254138005345398 Up 0.124025888257826 CG17267 CG17267 - - - - 31426 1200.00 0.415 0.605 0.54382380592767 Up 0.130960243032624 SIP3 syntaxin interacting protein 3 - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043161//proteasomal ubiquitin-dependent protein catabolic process 44271 5073.00 2 2.275 0.185866545311334 Up 0.126766609430722 xmas-2 xmas-2 - - GO:0003723//RNA binding GO:0007292//female gamete generation;GO:0006406//mRNA export from nucleus;GO:0048232//male gamete generation 42067 851.00 0.01 0.16 4 Up 0.178939373926826 CG17477 CG17477 K11997|1|3e-38|158|ame:409206|tripartite motif-containing protein 2/3;K09641|2|4e-32|138|mcc:711510|transmembrane protease, serine 11D [EC:3.4.21.-];K01312|5|1e-30|133|gga:396345|trypsin [EC:3.4.21.4] - - - 42131 2716.00 0.09 0.165 0.874469117916141 Up 0.0881983885880333 Pxt Peroxinectin-like K00430|1|2e-72|274|cel:F09F3.5|peroxidase [EC:1.11.1.7];K00431|2|8e-72|272|tgu:100218312|thyroid peroxidase [EC:1.11.1.8] - - - 12798120 542.00 0.155 0.09 -0.784271308944563 Down 0.0815612204464404 CG43137 CG43137 - - - - 34613 1533.00 36.25 45.215 0.318820468566629 Up 0.508024039096553 CG12264 CG12264 K04487|1|0.0|883|dme:Dmel_CG12264|cysteine desulfurase [EC:2.8.1.7] GO:0031980;GO:0015630//microtubule cytoskeleton GO:0016783//sulfurtransferase activity;GO:0042802//identical protein binding;GO:0016846//carbon-sulfur lyase activity;GO:0048037//cofactor binding GO:0016226//iron-sulfur cluster assembly;GO:0000096//sulfur amino acid metabolic process;GO:0006522//alanine metabolic process 33245 12427.00 4.02 2.33 -0.786865546524648 Down 0.418042530709285 ds dachsous, isoform B K06813|1|0.0|893|gga:423718|cadherin 23 GO:0031224//intrinsic to membrane GO:0046872//metal ion binding GO:0016337//cell-cell adhesion 10178928 519.00 0.16 0.01 -4 Down 0.178939373926826 CG42655 CG42655 - - - - 41632 1157.00 0.61 0.165 -1.88634321820443 Down 0.253896446968696 Osi22 osiris 22 - - - - 3885565 1455.36 126.83 131.735 0.0547426620670096 Up 0.156584334962356 CG17471 phosphatidylinositol 5-phosphate 4-kinase, isoform B K00889|1|0.0|795|dme:Dmel_CG17471|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68];K00920|2|0.0|791|dse:Dsec_GM13005|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] - - - 33390 2794.12 13.815 14.765 0.0959457943214625 Up 0.184618940694756 AIF apoptosis inducing factor, isoform C K04727|1|0.0|1046|dme:Dmel_CG7263|programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] GO:0005740//mitochondrial envelope;GO:0005740//mitochondrial envelope GO:0030554//adenyl nucleotide binding;GO:0003824//catalytic activity;GO:0030554//adenyl nucleotide binding;GO:0003824//catalytic activity GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0000737//DNA catabolic process, endonucleolytic;GO:0019725//cellular homeostasis;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0000737//DNA catabolic process, endonucleolytic;GO:0019725//cellular homeostasis 32817 2917.28 32.705 34.055 0.0583554177446552 Up 0.158730682868842 CrebB-17A Cyclic-AMP response element binding protein B, isoform P K09050|1|2e-100|365|dya:Dyak_GE17723|cAMP response element-binding protein, invertebrate GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030528//transcription regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding GO:0007613//memory;GO:0007626//locomotory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0010551;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0010551;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0010551;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0010551;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0042749//regulation of circadian sleep/wake cycle;GO:0010551 40921 1510.00 5.81 4.625 -0.329084798000854 Down 0.305441817461366 CG2641 CG2641 - - - - 50289 421.00 1.59 0.915 -0.797183117000313 Down 0.272949412230881 CG12521 CG12521 - - - - 35809 1139.00 1.285 2.625 1.03054906335961 Up 0.397569673755118 boly borrelly - - - - 32585 2388.54 96.515 79.735 -0.275540038012729 Down 0.497226258090081 eas easily shocked, isoform J K00894|1|0.0|865|dme:Dmel_CG3525|ethanolamine kinase [EC:2.7.1.82] - GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity;GO:0016301//kinase activity GO:0007613//memory;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0045165//cell fate commitment;GO:0006650//glycerophospholipid metabolic process;GO:0046335//ethanolamine biosynthetic process;GO:0046958//nonassociative learning;GO:0009612//response to mechanical stimulus;GO:0007613//memory;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0045165//cell fate commitment;GO:0006650//glycerophospholipid metabolic process;GO:0046335//ethanolamine biosynthetic process;GO:0046958//nonassociative learning;GO:0009612//response to mechanical stimulus;GO:0007613//memory;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0045165//cell fate commitment;GO:0006650//glycerophospholipid metabolic process;GO:0046335//ethanolamine biosynthetic process;GO:0046958//nonassociative learning;GO:0009612//response to mechanical stimulus;GO:0007613//memory;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0045165//cell fate commitment;GO:0006650//glycerophospholipid metabolic process;GO:0046335//ethanolamine biosynthetic process;GO:0046958//nonassociative learning;GO:0009612//response to mechanical stimulus;GO:0007613//memory;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0045165//cell fate commitment;GO:0006650//glycerophospholipid metabolic process;GO:0046335//ethanolamine biosynthetic process;GO:0046958//nonassociative learning;GO:0009612//response to mechanical stimulus 19836046 1351.00 0.32 0.135 -1.24511249783653 Down 0.146645093118478 35496 3443.00 7.24 3.65 -0.988093233315826 Down 0.552469951129309 CG30440 CG30440 K08810|1|3e-50|201|xtr:100170157|triple functional domain protein [EC:2.7.11.-] GO:0044464//cell part GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction 36127 3757.00 122.76 149.195 0.281358636176944 Up 0.505811649716022 Rab3 Rab3 K07976|1|2e-125|450|dya:Dyak_GE13081|Rab family, other GO:0044456//synapse part;GO:0030136//clathrin-coated vesicle GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding GO:0035556//intracellular signal transduction;GO:0007269//neurotransmitter secretion 19835176 889.00 0.05 0.01 -2.32192809488736 Down 0.0799432043323207 31234 3060.90 20.915 24.485 0.227360198064731 Up 0.383436798309338 Pdfr Pigment-dispersing factor receptor, isoform D K04576|1|1e-55|218|cfa:482306|calcitonin receptor - - - 35554 4812.79 4.415 4.08 -0.11384428567697 Down 0.125148593316603 Pld phospholipase D, isoform G K01115|1|0.0|2486|dme:Dmel_CG12110|phospholipase D [EC:3.1.4.4] GO:0031982//vesicle;GO:0031982//vesicle;GO:0031982//vesicle;GO:0031982//vesicle;GO:0031982//vesicle;GO:0031982//vesicle GO:0004620//phospholipase activity;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0005543//phospholipid binding GO:0007165//signal transduction;GO:0001703//gastrulation with mouth forming first;GO:0031340//positive regulation of vesicle fusion;GO:0007165//signal transduction;GO:0001703//gastrulation with mouth forming first;GO:0031340//positive regulation of vesicle fusion;GO:0007165//signal transduction;GO:0001703//gastrulation with mouth forming first;GO:0031340//positive regulation of vesicle fusion;GO:0007165//signal transduction;GO:0001703//gastrulation with mouth forming first;GO:0031340//positive regulation of vesicle fusion;GO:0007165//signal transduction;GO:0001703//gastrulation with mouth forming first;GO:0031340//positive regulation of vesicle fusion;GO:0007165//signal transduction;GO:0001703//gastrulation with mouth forming first;GO:0031340//positive regulation of vesicle fusion 317827 525.00 1.245 0.885 -0.492396381985083 Down 0.181151763307357 CG32023 CG32023 - - - - 34274 4382.54 46.605 43.76 -0.0908720040504405 Down 0.220677585523709 jp junctophilin, isoform E K04575|1|5e-15|84.7|ame:413195|amyotrophic lateral sclerosis 2 (juvenile) - - - 32297 2510.00 33.295 19.15 -0.797961148004838 Down 0.661273279619601 CG1673 CG1673 K00826|1|0.0|854|dme:Dmel_CG1673|branched-chain amino acid aminotransferase [EC:2.6.1.42] GO:0043231//intracellular membrane-bounded organelle GO:0008483//transaminase activity GO:0008652//cellular amino acid biosynthetic process 37090 1571.00 1.205 1.675 0.475127949115173 Up 0.207535332188614 Ote otefin - - - - 35291 2000.00 3.04 2.165 -0.489704298716861 Down 0.285035001981244 CG10730 CG10730 - - - - 40622 1617.88 18.095 20.635 0.189502330634496 Up 0.328820499273544 CG1116 CG1116, isoform D - - - - 47998 4770.44 30.705 33.32 0.117914797620981 Up 0.26159027869502 rin rasputin, isoform G - GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007264//small GTPase mediated signal transduction;GO:0051234//establishment of localization;GO:0007389//pattern specification process;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0051234//establishment of localization;GO:0007389//pattern specification process;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0051234//establishment of localization;GO:0007389//pattern specification process;GO:0001751//compound eye photoreceptor cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0051234//establishment of localization;GO:0007389//pattern specification process;GO:0001751//compound eye photoreceptor cell differentiation 35541 868.18 1.725 2.225 0.367208974188229 Up 0.205025756174878 CG14589 CG14589, isoform C - - - - 33197 1263.40 22.72 19.86 -0.194097211976308 Down 0.337967243428873 CG11601 CG11601, isoform C - GO:0031224//intrinsic to membrane - - 246550 1232.00 0.42 0.54 0.362570079384708 Up 0.101010434552899 CG30340 CG30340 K08375|1|2e-29|129|bfo:BRAFLDRAFT_211803|neuropeptide FF receptor 2;K04233|2|1e-27|124|dpo:Dpse_GA15495|galanin receptor, invertebrate GO:0031224//intrinsic to membrane - GO:0007166//cell surface receptor signaling pathway 35571 712.00 3.135 2.56 -0.292321632802039 Down 0.206412627129838 CG17266 CG17266, isoform B K09567|1|4e-106|384|dsi:Dsim_GD10314|peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity GO:0000377;GO:0044267//cellular protein metabolic process 12798587 476.00 0.09 0.2 1.15200309344505 Up 0.112996962092194 39824 2135.97 8.375 3.74 -1.16305092034486 Down 0.598765024435345 Grp Gag related protein, isoform B - - - - 41062 6176.61 49.875 58.155 0.221586394475266 Up 0.420023774930656 pyd polychaetoid, isoform O K00942|1|0.0|1412|dme:Dmel_CG31349|guanylate kinase [EC:2.7.4.8];K05701|3|4e-135|483|tgu:100231257|tight junction protein 1 GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction;GO:0070161;GO:0005911//cell-cell junction GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146;GO:0035153//epithelial cell type specification, open tracheal system;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007155//cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0035146 35728 1330.35 981.225 895.655 -0.131640868549717 Down 0.325353321886145 Gapdh1 glyceraldehyde 3 phosphate dehydrogenase 1, isoform B K00134|1|1e-171|602|dme:Dmel_CG12055|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0008943;GO:0000166//nucleotide binding;GO:0008943;GO:0000166//nucleotide binding GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 32085 1251.00 0.065 0.045 -0.53051471669878 Down 0.0549134856690001 Gr10b gustatory receptor 10b - GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 38391 4593.00 11.34 11.985 0.079809268706904 Up 0.148494254391758 gry gryzun - - - - 36351 1186.00 263.635 203.665 -0.372343840995769 Down 0.583542464667811 Cpr49Ae cuticular protein 49Ae - - GO:0005198//structural molecule activity - 34164 1238.00 0.59 0.965 0.709813987906239 Up 0.197827235503896 CG13385 CG13385 - - - - 32358 1398.92 147.605 141.49 -0.0610415001462292 Down 0.178311979923392 ben bendless, isoform E K10580|1|1e-83|309|dya:Dyak_GE17114|ubiquitin-conjugating enzyme E2 N [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity;GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0008344//adult locomotory behavior;GO:0042461//photoreceptor cell development;GO:0032446//protein modification by small protein conjugation;GO:0007154//cell communication;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0060255;GO:0008344//adult locomotory behavior;GO:0042461//photoreceptor cell development;GO:0032446//protein modification by small protein conjugation;GO:0007154//cell communication;GO:0048667//cell morphogenesis involved in neuron differentiation 44108 2359.66 11.075 11.79 0.090257019537382 Up 0.161009113723418 Optix optix, isoform C - GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0001745//compound eye morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0009987//cellular process;GO:0010468//regulation of gene expression;GO:0001745//compound eye morphogenesis 317933 645.00 2.785 3.66 0.39416632094401 Up 0.272421080438515 CG32240 CG32240 - - - - 64867 568.00 0.59 1.025 0.796837050143605 Up 0.216153744551578 nol no optic lobe - - - - 40807 905.28 1.1 1.465 0.413397140897588 Up 0.175406155065381 glob2 globin 2, isoform D - - GO:0005506//iron ion binding;GO:0022892 GO:0015669//gas transport 42589 1091.00 62.04 61.425 -0.0143727337865637 Down 0.0674943864747061 CG6028 CG6028 - - GO:0003824//catalytic activity - 326192 1775.63 5.175 6.755 0.384396906938997 Up 0.354708757099458 CG32075 CG32075, isoform B - - - - 42226 3653.54 23.26 36.115 0.634747073567937 Up 0.629672434288733 fru fruitless, isoform O K09237|1|6e-35|150|dme:Dmel_CG1856|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0005622//intracellular;GO:0005622//intracellular;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0005622//intracellular;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0030528//transcription regulator activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition;GO:0007548//sex differentiation;GO:0008049//male courtship behavior;GO:0048513//organ development;GO:0016198//axon choice point recognition 3772284 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 35238 2361.11 506.835 566.03 0.15936236429181 Up 0.371945581825386 CG10186 CG10186, isoform H K04012|1|1e-33|146|mmu:12902|complement component (3d/Epstein Barr virus) receptor 2 - GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity - 8673998 747.00 28.685 31.015 0.112669606919785 Up 0.243197728173293 31469 2361.07 2.665 3.095 0.215803876455089 Up 0.165301809536389 Vsx2 visual system homeobox 2 ortholog, isoform B K09336|1|0.0|731|dme:Dmel_CG33980|visual system homeobox protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0006909//phagocytosis;GO:0032501//multicellular organismal process 31653 2392.12 26.2 31.155 0.249896905140991 Up 0.420056795667679 CG4607 CG4607, isoform B K08145|1|2e-33|144|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8;K08144|4|4e-24|113|xla:447505|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6 - - - 14462404 794.00 0.105 0.06 -0.807354922057604 Down 0.07657508915599 35085 3503.00 12.935 14.865 0.200639409222903 Up 0.311253467177387 Socs36E suppressor of cytokine signaling at 36E, isoform D K04700|1|0.0|900|dse:Dsec_GM17100|suppressor of cytokine signaling, invertebrate - GO:0005488//binding;GO:0005488//binding GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048069//eye pigmentation;GO:0035216;GO:0019827//stem cell maintenance;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010741//negative regulation of intracellular protein kinase cascade;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048069//eye pigmentation;GO:0035216;GO:0019827//stem cell maintenance;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010741//negative regulation of intracellular protein kinase cascade 35071 7378.91 8.515 9.94 0.223239321883744 Up 0.290285299167877 CadN2 Cadherin-N2, isoform D K10414|1|0.0|2800|dmo:Dmoj_GI22290|dynein heavy chain 2, cytosolic;K04601|5|7e-103|376|bfo:BRAFLDRAFT_130073|cadherin EGF LAG seven-pass G-type receptor 2 (flamingo) GO:0016021//integral to membrane GO:0004871//signal transducer activity;GO:0046872//metal ion binding GO:0007411//axon guidance;GO:0016337//cell-cell adhesion;GO:0007389//pattern specification process;GO:0007154//cell communication;GO:0042051//compound eye photoreceptor development;GO:0030516//regulation of axon extension;GO:0031345//negative regulation of cell projection organization 19835434 508.00 14.055 3.775 -1.8965349041679 Down 0.710507198520671 19835980 1742.00 4.15 2.065 -1.00696955481484 Down 0.472130497952714 39215 1123.17 42.565 14.47 -1.5566027085633 Down 0.743560956280544 NijA ninjurin A, isoform D - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0009987//cellular process;GO:0009888//tissue development;GO:0009987//cellular process;GO:0009888//tissue development;GO:0009987//cellular process;GO:0009888//tissue development 43647 1157.74 0.525 0.665 0.341036917835067 Up 0.106392814687624 CG15543 CG15543, isoform B K00939|1|9e-08|57.8|dre:553671|adenylate kinase [EC:2.7.4.3] - GO:0016301//kinase activity;GO:0032559 GO:0034641//cellular nitrogen compound metabolic process 40780 778.00 167.4 112.18 -0.577484039755921 Down 0.663287544577995 CG17919 CG17919 - - - - 326163 1403.00 0.225 0.195 -0.206450877467426 Down 0.0567956676793026 CG31823 CG31823 K01289|1|0.0|873|dme:Dmel_CG31823|carboxypeptidase [EC:3.4.16.-];K09646|2|2e-123|442|der:Dere_GG14645|serine carboxypeptidase 1 [EC:3.4.16.-] - GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process 42619 1102.00 7.635 6.635 -0.202531691426658 Down 0.243263769647339 CG5380 CG5380, isoform B K03025|1|4e-158|557|dme:Dmel_CG5380|DNA-directed RNA polymerase III subunit C34 [EC:2.7.7.6] GO:0044451//nucleoplasm part GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 14462814 541.00 0.23 0.09 -1.3536369546147 Down 0.129573372077665 38288 3380.00 13.71 12.89 -0.088976307417575 Down 0.168702945449742 oxt peptide O-xylosyltransferase K00771|1|0.0|1724|dme:Dmel_CG32300|protein xylosyltransferase [EC:2.4.2.26] GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0035252//UDP-xylosyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0019321//pentose metabolic process;GO:0030166//proteoglycan biosynthetic process 40676 8228.00 12.99 14.62 0.170541880504556 Up 0.276680755514463 CG2926 CG2926, isoform B K11446|1|2e-09|66.6|cin:778759|histone demethylase JARID1 [EC:1.14.11.-];K11657|3|3e-09|66.2|mdo:100027446|remodeling and spacing factor 1;K13196|4|4e-09|65.9|spu:583658|zinc finger protein ubi-d4;K11655|5|5e-09|65.5|spu:577837|bromodomain adjacent to zinc finger domain protein 1A GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0000380//alternative mRNA splicing, via spliceosome 35409 977.02 0.165 3.35 4.34362316598668 Up 0.66497160216616 CG17571 CG17571, isoform B K01312|1|9e-61|233|dpo:Dpse_GA11597|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42257 2565.42 33.525 23.29 -0.52552669258097 Down 0.598302734117026 CG7720 CG7720, isoform F K03307|1|5e-77|289|nve:NEMVE_v1g168881|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport 34122 716.90 57.71 59.475 0.0434620356412759 Up 0.130398890503236 CG8360 CG8360, isoform C K01489|1|4e-87|320|dsi:Dsim_GD23515|cytidine deaminase [EC:3.5.4.5] - GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding GO:0046131 32497 3691.75 4.765 5.05 0.0838071737292149 Up 0.104807819310527 CG9220 CG9220, isoform D K13499|1|0.0|1593|dme:Dmel_CG9220|chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226] GO:0000139//Golgi membrane GO:0016757//transferase activity, transferring glycosyl groups - 43943 823.00 30.28 28.255 -0.0998590161349656 Down 0.224243825122177 or orange K12399|1|4e-105|380|dya:Dyak_GE14351|AP-3 complex subunit sigma GO:0043234//protein complex;GO:0030136//clathrin-coated vesicle GO:0005488//binding;GO:0022892 GO:0042441//eye pigment metabolic process;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0007033//vacuole organization;GO:0015031//protein transport 37065 5063.79 37.985 45.935 0.274164007440278 Up 0.462257297582882 stau staufen, isoform C K13194|1|3e-07|58.2|xtr:100124739|double stranded RNA-specific editase 1 [EC:3.5.-.-];K13200|2|4e-07|57.8|mmu:20744|spermatid perinuclear RNA-binding protein;K13090|4|5e-07|57.4|tgu:100219622|interleukin enhancer-binding factor 3 GO:0044448//cell cortex part;GO:0015630//microtubule cytoskeleton;GO:0030529//ribonucleoprotein complex GO:0015631//tubulin binding;GO:0003729//mRNA binding GO:0007613//memory;GO:0045727//positive regulation of translation;GO:0019094//pole plasm mRNA localization;GO:0010603//regulation of cytoplasmic mRNA processing body assembly;GO:0008105//asymmetric protein localization;GO:0001709//cell fate determination 43100 719.00 6.015 3.4 -0.823029991038375 Down 0.492075023114516 CG5039 CG5039 - GO:0019866//organelle inner membrane;GO:0031224//intrinsic to membrane GO:0005215//transporter activity GO:0006810//transport 33503 1240.79 31.565 10.74 -1.55533175777758 Down 0.73401796328094 CG3165 CG3165, isoform B K10790|1|7e-105|380|dpo:Dpse_GA16366|three prime repair exonuclease 1 [EC:3.1.11.2];K10791|2|3e-18|93.2|oaa:100079748|three prime repair exonuclease 2 [EC:3.1.11.2] - GO:0005488//binding - 35597 2198.00 0.125 0.52 2.05658352836637 Up 0.245773345661075 CG9447 CG9447 K00680|1|3e-17|90.5|dme:Dmel_CG33337| [EC:2.3.1.-] - GO:0016746//transferase activity, transferring acyl groups - 41926 1283.00 1.165 1.915 0.717014437270677 Up 0.284044379870559 CG9632 CG9632, isoform B - - - - 37689 1212.97 0.445 0.775 0.80039097430784 Up 0.187722889974904 CG13541 CG13541, isoform B - - - - 14462833 418.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 33218 6672.00 7.46 6.07 -0.297479113999556 Down 0.317593448685775 ex expanded, isoform B K02374|1|2e-10|70.1|cfa:403662|protein tyrosin phosphatase, non-receptor type 13 (PTPN13) GO:0005913//cell-cell adherens junction GO:0005488//binding GO:0045926//negative regulation of growth;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0022402//cell cycle process;GO:0001745//compound eye morphogenesis;GO:0045570//regulation of imaginal disc growth;GO:0016310//phosphorylation;GO:0016197//endosomal transport;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008283//cell proliferation;GO:0007346//regulation of mitotic cell cycle 318856 4704.00 0.355 0.525 0.564498398161441 Up 0.123992867520803 dtr defective transmitter release K01768|1|7e-15|84.0|mcc:700574|adenylate cyclase [EC:4.6.1.1];K11293|4|6e-12|74.3|cbr:CBG03541|protein HIRA/HIR1 GO:0005930//axoneme GO:0005515//protein binding GO:0048858//cell projection morphogenesis 38321 3267.46 11.79 11.06 -0.0922123327450555 Down 0.162594109100515 dos daughter of sevenless, isoform B K09593|1|4e-18|94.7|bfo:BRAFLDRAFT_63588|GRB2-associated-binding protein 1;K08091|2|8e-16|87.0|mmu:14389|growth factor receptor bound protein 2-associated protein 2 GO:0044424//intracellular part;GO:0044424//intracellular part GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006959//humoral immune response;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0000578//embryonic axis specification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006959//humoral immune response;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0000578//embryonic axis specification 40789 2381.27 5.175 5.845 0.175644162144969 Up 0.197298903711531 CG1024 CG1024, isoform E K09228|1|2e-06|54.7|mcc:711981|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 35552 5443.91 20.38 19.11 -0.0928262731883573 Down 0.191652357680623 bin3 bicoid-interacting protein 3, isoform C - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0016741;GO:0005488//binding;GO:0016741 GO:0008213;GO:0010468//regulation of gene expression;GO:0007635//chemosensory behavior;GO:0008213;GO:0010468//regulation of gene expression;GO:0007635//chemosensory behavior 42762 1680.00 8.825 20.765 1.23448568826625 Up 0.687656848500859 CG4408 CG4408, isoform B K01290|1|1e-67|258|dmo:Dmoj_GI16514|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 40351 3923.24 16.57 13.02 -0.347844154055816 Down 0.45145951657641 pzg putzig, isoform B K09228|1|2e-13|79.3|xla:397958|KRAB domain-containing zinc finger protein GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0051276//chromosome organization 35741 886.32 20.65 23.125 0.163311583984229 Up 0.301776515651829 CG12159 CG12159, isoform B - - - - 36717 2587.17 12.88 10.195 -0.33727081809802 Down 0.41658961828028 GalNAc-T1 GalNAc-T1, isoform C K00710|1|0.0|1140|dme:Dmel_CG8182|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process;GO:0009311//oligosaccharide metabolic process 32638 1332.00 15.695 13.245 -0.244857185212493 Down 0.356987187954035 CG32573 CG32573, isoform C - - - - 246384 1572.00 14.515 16.43 0.178787908323413 Up 0.297318716153745 CG30002 CG30002 K01362|1|4e-26|119|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|2|8e-26|118|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4];K01323|5|2e-23|110|ecb:100056603|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42929 3013.49 43.54 40.845 -0.0921819244232544 Down 0.219224673094703 Esyt2 extended synaptotagmin-like protein 2 ortholog, isoform D K00923|1|1e-12|75.9|mdo:100017523|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] - - - 38261 1773.41 54.04 32.085 -0.752128691439484 Down 0.675340113591335 CG1140 Succinyl-CoA:3-ketoacid CoA transferase, isoform C K01027|1|0.0|944|dme:Dmel_CG1140|3-oxoacid CoA-transferase [EC:2.8.3.5] GO:0031980;GO:0031980 GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0016782//transferase activity, transferring sulfur-containing groups GO:0044248//cellular catabolic process;GO:0044248//cellular catabolic process 39811 1180.00 5.345 4.77 -0.164200681714979 Down 0.178708228767666 CG4933 CG4933 K01409|1|0.0|697|dme:Dmel_CG4933|O-sialoglycoprotein endopeptidase [EC:3.4.24.57] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 39862 718.48 54.98 55.41 0.0112394601906409 Up 0.0661405362567692 zetaCOP coat protein (coatomer) zeta, isoform C - - - GO:0019915//lipid storage;GO:0006909//phagocytosis;GO:0019915//lipid storage;GO:0006909//phagocytosis;GO:0019915//lipid storage;GO:0006909//phagocytosis 41699 1101.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 Art6 arginine methyltransferase 6 K11434|1|7e-64|244|dya:Dyak_GE24666|protein arginine N-methyltransferase 1 [EC:2.1.1.-] - - - 38049 1513.00 1.285 1.57 0.288996199697749 Up 0.14515915995245 ttm2 tiny tim 2 K01090|1|7e-18|92.0|bta:516199|protein phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization 39030 620.18 9.59 5.425 -0.821907677686289 Down 0.558149517897239 CG13314 CG13314, isoform B - - - - 31194 1638.00 21.665 26.795 0.306597579439425 Up 0.46605468234051 pn prune K01529|1|0.0|776|dme:Dmel_CG3461| [EC:3.6.1.-];K01514|2|2e-43|177|tgu:100225049|exopolyphosphatase [EC:3.6.1.11] - - - 35559 2305.14 35.165 37.35 0.0869680257086917 Up 0.212389380530973 Trap1 Trap1, isoform B K09488|1|0.0|1348|dme:Dmel_CG3152|TNF receptor-associated protein 1 GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0032559 GO:0044267//cellular protein metabolic process;GO:0050896//response to stimulus 35390 2820.00 0.505 0.4 -0.336283387864432 Down 0.0924250429269581 Mcm10 minichromosome maintenance 10 K10736|1|0.0|1412|dme:Dmel_CG9241|minichromosome maintenance protein 10 - - - 32349 1604.15 48.115 34.625 -0.474672657594987 Down 0.594802535992603 Clic chloride intracellular channel, isoform C K05025|1|2e-24|113|mmu:224796|chloride intracellular channel 5;K05022|2|3e-24|113|gga:422178|chloride intracellular channel 2 - GO:0046872//metal ion binding;GO:0005253//anion channel activity GO:0006950//response to stress;GO:0010259//multicellular organismal aging 40587 1301.00 130.785 135.005 0.0458157547666427 Up 0.155725795799762 CG9769 CG9769 K03249|1|3e-160|564|dsi:Dsim_GD19663|translation initiation factor eIF-3 subunit 5 GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding GO:0048102//autophagic cell death;GO:0006412//translation 32805 1980.00 0.045 0.26 2.53051471669878 Up 0.180458327829877 upd2 unpaired 2 - - - GO:0007276//gamete generation;GO:0048731;GO:0050789//regulation of biological process;GO:0048610//cellular process involved in reproduction;GO:0051301//cell division;GO:0048468//cell development;GO:0009653//anatomical structure morphogenesis;GO:0003006//developmental process involved in reproduction;GO:0007389//pattern specification process;GO:0009790//embryo development 41388 2783.00 0.635 0.805 0.342232191342451 Up 0.116034869898296 CG6790 CG6790 K05285|1|8e-93|342|dpo:Dpse_GA15342|phosphatidylinositol glycan, class N [EC:2.7.-.-] GO:0031090//organelle membrane GO:0003824//catalytic activity GO:0006497//protein lipidation 318955 1138.00 2.485 3.02 0.281302697762793 Up 0.198454629507331 CG31810 CG31810 K10251|1|1e-59|230|mcc:714962|beta-keto reductase [EC:1.1.1.-];K00100|2|1e-50|200|dme:Dmel_CG1444| [EC:1.1.1.-];K00044|3|3e-50|199|cin:445663|estradiol 17beta-dehydrogenase [EC:1.1.1.62] - GO:0016491//oxidoreductase activity GO:0008152//metabolic process;GO:0006909//phagocytosis 32965 7380.61 12.31 13.64 0.148012882539715 Up 0.247754589882446 e(y)3 enhancer of yellow 3, isoform E K13196|1|9e-22|107|dmo:Dmoj_GI20660|zinc finger protein ubi-d4 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0046914//transition metal ion binding GO:0006355//regulation of transcription, DNA-dependent;GO:0007292//female gamete generation 43924 12809.64 20.215 23.985 0.246706235929793 Up 0.400739664509312 jim jim, isoform I K09228|1|9e-68|259|cfa:482782|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 40395 840.00 29.14 34.845 0.257950777465451 Up 0.436600184916127 CG7172 CG7172 K09554|1|1e-11|70.1|phu:Phum_PHUM253670|cell division cycle protein 37 GO:0043231//intracellular membrane-bounded organelle - GO:0009987//cellular process 35078 1438.17 3688.455 5169.905 0.487121135875509 Up 0.645885616166953 Arr1 arrestin 1, isoform C K13808|1|0.0|690|dme:Dmel_CG5711|arrestin-1 GO:0005626//insoluble fraction;GO:0042995//cell projection;GO:0044424//intracellular part GO:0002046//opsin binding GO:0016192//vesicle-mediated transport;GO:0043954//cellular component maintenance;GO:0016059//deactivation of rhodopsin mediated signaling 33431 2109.29 16.78 16.485 -0.0255888287694361 Down 0.0864152687887994 CG9886 CG9886, isoform B K00865|1|0.0|939|dme:Dmel_CG9886|glycerate kinase [EC:2.7.1.31] GO:0044424//intracellular part GO:0016301//kinase activity - 32379 2243.00 24.905 25.365 0.0264037494585521 Up 0.095330867784969 mRNA-cap mRNA-capping-enzyme K13917|1|0.0|1249|dme:Dmel_CG1810|mRNA-capping enzyme [EC:2.7.7.50 3.1.3.33] GO:0043231//intracellular membrane-bounded organelle GO:0019204//nucleotide phosphatase activity;GO:0008192;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process;GO:0006397//mRNA processing;GO:0006796//phosphate-containing compound metabolic process 40689 995.20 20.34 37.25 0.872920746379386 Up 0.677420420023775 CG31549 CG31549, isoform B K00079|1|5e-26|118|cel:R11D1.11|carbonyl reductase (NADPH) [EC:1.1.1.184];K11147|2|8e-26|117|cel:F36H9.3|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-];K00120|3|6e-24|111|dme:Dmel_CG7322| [EC:1.1.-.-];K13774|4|1e-23|110|hmg:100207100|citronellol/citronellal dehydrogenase - GO:0003824//catalytic activity GO:0008152//metabolic process 36832 914.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 CG15710 CG15710 K12463|1|1e-08|60.5|xtr:779710|PR domain zinc finger protein 4 GO:0044464//cell part GO:0046914//transition metal ion binding - 34264 2059.80 165.835 155.82 -0.0898681044598021 Down 0.239235239730551 Gdi GDP dissociation inhibitor, isoform C - GO:0015630//microtubule cytoskeleton;GO:0030136//clathrin-coated vesicle GO:0005092//GDP-dissociation inhibitor activity GO:0006810//transport;GO:0033124//regulation of GTP catabolic process;GO:0001505//regulation of neurotransmitter levels 19834726 514.00 0.085 0.01 -3.08746284125034 Down 0.117619865275393 3772611 715.00 0.115 0.01 -3.52356195605701 Down 0.136970017170783 CG33710 CG33710 - - - - 31151 3122.59 154.275 164.875 0.0958683648928171 Up 0.258849557522124 arm armadillo, isoform F K02105|1|0.0|1578|der:Dere_GG12670|catenin (cadherin-associated protein), beta 1 - - - 48071 4051.81 12.205 11.14 -0.131723062441122 Down 0.215658433496236 Su(z)12 Su(z)12, isoform B K11463|1|0.0|1360|dme:Dmel_CG8013|polycomb protein SUZ12 GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005700//polytene chromosome GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity GO:0006479//protein methylation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0006479//protein methylation;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 41906 1288.00 3.7 4.51 0.285602162739069 Up 0.245806366398098 CG5614 CG5614 - - - - 40293 1439.00 12.405 11.085 -0.162312965025124 Down 0.253368115176331 Pex16 peroxin 16 K13335|1|0.0|674|dme:Dmel_CG3947|peroxin-16 - - - 43696 1822.00 0.105 0.055 -0.932885804141463 Down 0.0768722757891956 CG15564 CG15564 - - - - 36908 1547.00 22.725 22.67 -0.00349590334068358 Down 0.0441487253995509 ste24a prenyl protease type I K06013|1|0.0|866|dme:Dmel_CG9000|STE24 endopeptidase [EC:3.4.24.84] - - - 41155 1024.72 7.29 8.35 0.195857383034477 Up 0.249339585259543 CG16790 CG16790, isoform B - GO:0044464//cell part - GO:0044260 41883 4890.19 30.365 35.375 0.220320778756534 Up 0.397569673755118 Atx2 Ataxin-2, isoform D - - - - 43978 2619.60 14.12 10.99 -0.361548702321949 Down 0.44208162726192 Plap phospholipase A2 activator protein, isoform C K14018|1|0.0|1525|dme:Dmel_CG5105|phospholipase A-2-activating protein - GO:0016004//phospholipase activator activity - 37110 734.00 16.745 9.745 -0.780996285448825 Down 0.611577070400211 GstE5 glutathione S transferase E5 K00799|1|1e-123|442|dme:Dmel_CG17527|glutathione S-transferase [EC:2.5.1.18] - - - 36102 4149.27 51.525 47.085 -0.130005070123347 Down 0.2937854972923 RanBPM Ran-binding protein M, isoform F K12169|1|7e-09|63.9|phu:Phum_PHUM177460|Kip1 ubiquitination-promoting complex protein 1 [EC:6.3.2.19];K13177|2|9e-09|63.5|hmg:100208995|ATP-dependent RNA helicase DDX1 [EC:3.6.4.13] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part - GO:0060249//anatomical structure homeostasis;GO:0016337//cell-cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0030537//larval behavior;GO:0006996//organelle organization;GO:0060249//anatomical structure homeostasis;GO:0016337//cell-cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0030537//larval behavior;GO:0006996//organelle organization;GO:0060249//anatomical structure homeostasis;GO:0016337//cell-cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0030537//larval behavior;GO:0006996//organelle organization 246600 1237.00 1.075 2.735 1.3472041732031 Up 0.450898164047022 CG30411 CG30411 - - - - 14462895 578.00 0.08 0.01 -3 Down 0.110718531237617 32878 2115.00 11.345 10.785 -0.0730304325118832 Down 0.134295337471932 CG7280 CG7280 K00387|1|0.0|1140|dme:Dmel_CG7280|sulfite oxidase [EC:1.8.3.1] GO:0005740//mitochondrial envelope GO:0005506//iron ion binding;GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor GO:0009057//macromolecule catabolic process;GO:0044237//cellular metabolic process 42983 1480.04 0.4 0.865 1.11270013274936 Up 0.239433364152688 Trf4-2 Trf4-2, isoform B K03514|1|0.0|756|dme:Dmel_CG17462|DNA polymerase sigma subunit [EC:2.7.7.7] GO:0043231//intracellular membrane-bounded organelle GO:0070566//adenylyltransferase activity;GO:0034061 GO:0007059//chromosome segregation;GO:0043629//ncRNA polyadenylation 37366 1098.00 0.495 0.47 -0.0747677684019721 Down 0.045898824461762 CG9235 CG9235 K01672|1|0.0|651|dme:Dmel_CG9235|carbonic anhydrase [EC:4.2.1.1] - - - 40234 1971.71 58.75 44.73 -0.393346093335126 Down 0.56452252014265 Spn77Ba serpin 77Ba, isoform C K13963|1|4e-35|149|ptr:739078|serpin B - GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity - 36037 1229.86 88.14 89.99 0.0299677964717911 Up 0.111180821555937 Adam adam, isoform B K03245|1|7e-80|297|dme:Dmel_CG12131|translation initiation factor eIF-3 subunit 1 GO:0005737//cytoplasm - GO:0006412//translation 38192 726.00 13.545 10.135 -0.418414304735116 Down 0.468696341302338 CG13926 CG13926 - - - - 19835482 649.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 34092 976.00 16.76 15.56 -0.10718008871316 Down 0.20829480914014 CG12560 CG12560, isoform C - - GO:0016407//acetyltransferase activity - 19835131 641.00 0.9 0.91 0.0159415438690215 Up 0.0413749834896315 - CG45493 - - - - 50364 387.00 118.975 119.155 0.00218103688589199 Up 0.046328094043059 CG13364 CG13364 - - - - 38387 541.00 0.08 0.21 1.39231742277876 Up 0.12534671773874 CG14958 CG14958 - - - - 41204 2058.27 25.325 21.57 -0.231536092528047 Down 0.387003037907806 CG12945 CG12945, isoform C - - - - 45018 476.00 0.1 0.01 -3.32192809488736 Down 0.129177123233391 Lcp65Ae Lcp65Ae - - GO:0005214//structural constituent of chitin-based cuticle GO:0002168//instar larval development 34220 2441.05 2.105 1.635 -0.364529597568313 Down 0.197530048870691 CG9541 CG9541, isoform D K00939|1|3e-28|127|hsa:26289|adenylate kinase [EC:2.7.4.3] - GO:0016301//kinase activity;GO:0032559 GO:0034641//cellular nitrogen compound metabolic process 40664 10244.17 17.845 20.275 0.184182013055613 Up 0.317527407211729 Itp-r83A inositol 1,4,5,-tris-phosphate receptor, isoform C K02522|1|0.0|5153|dme:Dmel_CG1063|inositol 1,4,5-triphosphate receptor, invertebrate GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0005217//intracellular ligand-gated ion channel activity;GO:0004872//receptor activity;GO:0005261//cation channel activity;GO:0005217//intracellular ligand-gated ion channel activity;GO:0004872//receptor activity;GO:0005261//cation channel activity GO:0018988;GO:0008344//adult locomotory behavior;GO:0007420//brain development;GO:0048285;GO:0051283;GO:0042391//regulation of membrane potential;GO:0070838//divalent metal ion transport;GO:0006950//response to stress;GO:0018988;GO:0008344//adult locomotory behavior;GO:0007420//brain development;GO:0048285;GO:0051283;GO:0042391//regulation of membrane potential;GO:0070838//divalent metal ion transport;GO:0006950//response to stress 5740510 1123.00 3.925 5.93 0.595339450767014 Up 0.424745740324924 32216 1234.00 11.39 12.43 0.126058549344373 Up 0.213941355171047 CG2540 CG2540 K07232|1|4e-30|132|tgu:100219118|cation transport protein ChaC - - - 260658 1690.00 0.585 0.8 0.451563375303958 Up 0.137003037907806 CG31819 CG31819 - - - - 43523 2977.00 1.085 0.585 -0.891186512861075 Down 0.240886276581693 neo neyo, isoform B - - - - 50039 448.00 3.8 0.81 -2.23000560544632 Down 0.582188614449875 CG34281 CG34281 - - - - 32364 589.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 CG12481 CG12481 - - - - 37691 1160.00 1.535 2.245 0.548476789370968 Up 0.262316734909523 CG30412 CG30412, isoform C - - - - 326246 1537.47 42.535 52.905 0.314753622386565 Up 0.506802271826707 CG33056 CG33056, isoform E - - - - 37266 594.67 867.265 637.365 -0.444353090494891 Down 0.625412759212786 Obp56d Odorant-binding protein 56d, isoform B - - - - 4379885 2199.90 11.575 22.3 0.946031516660069 Up 0.660282657508916 CG14042 CG14042, isoform C K10345|1|6e-143|508|dsi:Dsim_GD12021|SPRY domain-containing SOCS box protein 3 - - GO:0023033;GO:0023033 33518 1771.00 21.45 20.32 -0.078077245614742 Down 0.17573636243561 CG17259 CG17259, isoform B K01875|1|0.0|961|dme:Dmel_CG17259|seryl-tRNA synthetase [EC:6.1.1.11] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0007033//vacuole organization 117485 1104.00 0.105 0.01 -3.39231742277876 Down 0.13426231673491 Gr59a gustatory receptor 59a K08471|1|0.0|744|dme:Dmel_CG30189|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 14462386 759.00 0.16 0.2 0.321928094887362 Up 0.0662726192048606 37717 436.00 0.765 0.775 0.0187365625815857 Up 0.0413749834896315 CG13557 CG13557 - - - - 43046 1751.00 12.56 12.32 -0.0278342081967255 Down 0.0799762250693435 CG11859 RIO kinase 2 K07179|1|0.0|995|dme:Dmel_CG11859|RIO kinase 2 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 37594 1759.00 4.7 14.29 1.60427325453082 Up 0.695020472856954 Cyp6d2 Cyp6d2 K00517|1|0.0|989|dme:Dmel_CG4373| [EC:1.14.-.-];K07424|4|7e-87|321|tca:659054|cytochrome P450, family 3, subfamily A [EC:1.14.14.1] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 36630 2806.01 0.175 0.165 -0.0848888975865134 Down 0.0426627922335227 CG12866 CG12866, isoform E K08190|1|3e-21|104|cin:100184819|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14;K08185|2|8e-19|96.3|ptr:458827|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 8;K08187|5|3e-17|91.3|nve:NEMVE_v1g88648|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10 GO:0016020//membrane;GO:0016020//membrane - GO:0006810//transport;GO:0006810//transport 19835376 762.00 0.16 0.13 -0.299560281858908 Down 0.0597675340113591 36135 316.00 13.69 12.56 -0.124285982366273 Down 0.212059173160745 CG7637 CG7637 K11130|1|1e-31|134|dvi:Dvir_GJ20125|H/ACA ribonucleoprotein complex subunit 3 GO:0032991//macromolecular complex GO:0005488//binding GO:0042254//ribosome biogenesis 39665 1722.00 0.2 0.37 0.887525270741587 Up 0.134691586316207 CG7804 CG7804, isoform B K12741|1|3e-20|100|phu:Phum_PHUM451750|heterogeneous nuclear ribonucleoprotein A1/A3;K13158|2|1e-19|98.2|xtr:549680|heterogeneous nuclear ribonucleoprotein A2/B1 - GO:0003723//RNA binding GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior 37044 2338.00 7.93 4.76 -0.736359292396035 Down 0.514793290186237 proPO-A1 prophenoloxidase 1 K00505|1|0.0|1410|dme:Dmel_CG42639|tyrosinase [EC:1.14.18.1] - - - 32743 7178.08 28.57 36.335 0.34685887004791 Up 0.516708492933562 RhoGAPp190 Rho GTPase activating protein p190, isoform G K05732|1|4e-163|577|rno:306400|glucocorticoid receptor DNA-binding factor 1 GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005099//Ras GTPase activator activity GO:0023060;GO:0007420//brain development;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0023060;GO:0007420//brain development;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0023060;GO:0007420//brain development;GO:0010769//regulation of cell morphogenesis involved in differentiation 38744 3031.42 33.76 27.16 -0.313831424462453 Down 0.483357548540483 SP1173 SP1173, isoform D - - - - 41745 546.94 467.625 487.505 0.0600649548824802 Up 0.183826443006208 CG3321 CG3321, isoform C K02129|1|2e-23|108|dme:Dmel_CG3321|F-type H+-transporting ATPase subunit e [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process 2768836 3360.91 9.96 9.66 -0.0441225532323078 Down 0.0932175406155065 Fs follistatin, isoform B K04661|1|3e-36|154|rno:24373|follistatin - - GO:0032924//activin receptor signaling pathway;GO:0008101//decapentaplegic signaling pathway 35260 3116.55 7.895 6.795 -0.216465715092846 Down 0.260995905428609 CG10462 CG10462, isoform F K09228|1|1e-26|122|mmu:667666|KRAB domain-containing zinc finger protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 33471 555.72 75.28 79.355 0.0760544991899286 Up 0.210408136309602 CG2862 CG2862, isoform C K10863|1|1e-07|55.8|xtr:403092|aprataxin [EC:3.-.-.-] GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0019901//protein kinase binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0023060;GO:0023060 42325 4352.00 162.99 168.005 0.0437207168744759 Up 0.136276581693303 CG31221 CG31221, isoform C - - - - 39130 1617.00 0.625 0.36 -0.795859283219775 Down 0.163881917844406 alphaTub67C alpha-Tubulin at 67C K07374|1|1e-177|622|tgu:100223131|tubulin alpha GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0005198//structural molecule activity GO:0000278//mitotic cell cycle;GO:0007097//nuclear migration;GO:0048285;GO:0000226//microtubule cytoskeleton organization;GO:0043623//cellular protein complex assembly;GO:0007399//nervous system development;GO:0006997//nucleus organization;GO:0009790//embryo development 36641 666.00 30.315 27.57 -0.136932555090701 Down 0.288535200105666 CG10153 TRAPP subunit 31 ortholog K10631|1|7e-51|199|isc:IscW_ISCW010224|E3 ubiquitin-protein ligase Topors [EC:6.3.2.19] - GO:0009975//cyclase activity;GO:0005506//iron ion binding GO:0006164//purine nucleotide biosynthetic process 12798424 745.00 5.235 4.25 -0.300726695905744 Down 0.271331396116761 36559 648.00 1.62 4.065 1.3272615391904 Up 0.516939638092722 CG42288 CG42288, isoform B - - - - 19835831 301.00 0.15 0.01 -3.90689059560852 Down 0.171410645885616 30994 2345.00 6.89 7.76 0.171552669482836 Up 0.218234050984018 CG3156 CG3156 K05657|1|9e-162|570|tgu:100225114|ATP-binding cassette, subfamily B (MDR/TAP), member 10 - - - 19835098 470.00 1.365 1.995 0.547487795302493 Up 0.246763967771761 33982 2741.76 22.58 24.84 0.137619687447481 Up 0.27664773477744 snRNP-U1-70K small ribonucleoprotein particle U1 subunit 70K, isoform C K11093|1|2e-96|353|dsi:Dsim_GD22521|U1 small nuclear ribonucleoprotein 70kDa - GO:0005488//binding - 5740232 503.00 53.525 84.66 0.661467598045549 Up 0.668141592920354 CG41343 CG41343 - GO:0005624//membrane fraction GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006810//transport;GO:0019725//cellular homeostasis 41682 660.00 1.87 4.45 1.25076706596612 Up 0.519845462950733 CG9602 CG9602 K10575|1|3e-95|347|dme:Dmel_CG9602|ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19] - - - 19835973 1186.00 0.07 0.505 2.85085656069419 Up 0.272883370756835 31611 5958.91 10.48 12.72 0.279459953746905 Up 0.368610487386078 CG14441 CG14441, isoform D K09228|1|5e-07|57.8|hsa:7556|KRAB domain-containing zinc finger protein - - - 36666 1781.00 7.76 8.03 0.0493433353301866 Up 0.0935807687227579 Cyp6a8 cytochrome P450-6a8 K00517|1|0.0|974|dme:Dmel_CG10248| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 38646 1123.00 74.945 47.15 -0.668574460230405 Down 0.666292431647074 Txl Thioredoxin-like K03671|1|4e-23|108|xla:443948|thioredoxin 1 - - GO:0033554//cellular response to stress;GO:0019725//cellular homeostasis 40486 1323.00 0.955 0.305 -1.64669149047286 Down 0.304583278298772 CG11370 CG11370, isoform B - - - - 41702 3193.00 0.015 0.01 -0.584962500721156 Down 0.0382380134724607 CG9925 CG9925 - - - - 32413 2191.00 0.19 0.23 0.275634442613427 Up 0.0642253335094439 CG9522 CG9522 K00115|1|0.0|883|dme:Dmel_CG12539|glucose dehydrogenase (acceptor) [EC:1.1.99.10];K00108|2|2e-133|476|dme:Dmel_CG9519|choline dehydrogenase [EC:1.1.99.1] - GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 41171 14470.00 0.49 0.58 0.243271151012364 Up 0.0815612204464404 CG9492 CG9492, isoform G K10408|1|0.0|1939|tad:TRIADDRAFT_23475|dynein heavy chain, axonemal GO:0030286//dynein complex GO:0003774//motor activity;GO:0032559 GO:0048870//cell motility;GO:0007017//microtubule-based process 36760 4001.87 104.31 94.075 -0.148994183493541 Down 0.342028794082684 ATPCL ATP citrate lyase, isoform G K01648|1|0.0|2165|dsi:Dsim_GD25577|ATP citrate (pro-S)-lyase [EC:2.3.3.8] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0032559;GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0032559 GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process 35523 4044.59 25.835 28.96 0.164734718658345 Up 0.315678245938449 mle maleless, isoform C K13184|1|0.0|1897|dme:Dmel_CG11680|ATP-dependent RNA helicase A [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0000805//X chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044427//chromosomal part;GO:0000805//X chromosome GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0004386//helicase activity;GO:0032559;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0004386//helicase activity;GO:0032559 GO:0008049//male courtship behavior;GO:0010259//multicellular organismal aging;GO:0048588//developmental cell growth;GO:0009047//dosage compensation by hyperactivation of X chromosome;GO:0008049//male courtship behavior;GO:0010259//multicellular organismal aging;GO:0048588//developmental cell growth;GO:0009047//dosage compensation by hyperactivation of X chromosome 32686 5860.64 9.9 7 -0.500073603134643 Down 0.46559239202219 RhoGAP15B Rho GTPase activating protein at 15B, isoform C K12490|1|1e-128|461|tca:658565|Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein GO:0044464//cell part;GO:0044464//cell part GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0023060;GO:0023060 38668 1865.53 57.5 58.625 0.0279540615710013 Up 0.107515519746401 CG33523 VAMP-associated protein of 33kDa ortholog B, isoform F K06096|1|2e-09|65.1|dre:334608|vesicle-associated membrane protein-associated protein A - - - 59170 2150.10 20.08 24.345 0.277866231318356 Up 0.431911240258883 CG18809 CG18809, isoform D - - GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain;GO:0010259//multicellular organismal aging;GO:0022904//respiratory electron transport chain 318583 3149.00 0.075 0.265 1.82102985895468 Up 0.158928807290979 CG31077 CG31077 K06252|1|9e-18|92.8|rno:116640|tenascin - GO:0030247//polysaccharide binding GO:0006022 3771836 342.00 4.025 5.645 0.487984797771022 Up 0.376568485008585 19835081 499.00 0.51 0.645 0.338801913451758 Up 0.106392814687624 7354473 2089.00 6.495 4.3 -0.594992865858421 Down 0.438416325452384 moi modigliani - GO:0044427//chromosomal part GO:0016741 GO:0009451//RNA modification;GO:0006396//RNA processing;GO:0000723//telomere maintenance 37617 2252.00 1108.58 1158.475 0.0635140258730765 Up 0.185675604279488 blw bellwether K02132|1|0.0|1058|dme:Dmel_CG3612|F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0015630//microtubule cytoskeleton;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0006909//phagocytosis;GO:0015986//ATP synthesis coupled proton transport 19834939 1075.00 0.04 0.01 -2 Down 0.0694426099590543 - CG44438 - - - - 34237 2738.77 28.32 26.675 -0.0863329943712103 Down 0.202020869105798 CG32982 CG32982, isoform H - - - - 19835335 348.00 0.01 0.175 4.12928301694497 Up 0.187062475234447 246549 1023.00 2.95 0.555 -2.4101552778991 Down 0.552668075551446 CG30339 CG30339 K10693|1|9e-13|74.3|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K00683|2|7e-08|58.2|tca:659407|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] GO:0044464//cell part - GO:0051234//establishment of localization 31177 1240.00 24.12 18.345 -0.394843002651542 Down 0.513274336283186 CG4025 CG4025 - - - - 31744 1545.00 70.49 74.965 0.0887985753781181 Up 0.229229956412627 Gbeta5 Gbeta5 K04539|1|0.0|707|dya:Dyak_GE17476|guanine nucleotide binding protein (G protein), beta 5 GO:0019897//extrinsic to plasma membrane - GO:0007166//cell surface receptor signaling pathway 5740285 415.00 0.01 0.345 5.10852445677817 Up 0.295898824461762 CG34173 CG34173 - - - - 39635 560.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG13461 CG13461 - - - - 33909 483.00 11.725 11.33 -0.0494400615822234 Down 0.108208955223881 CG9548 CG9548 K12834|1|8e-66|248|dya:Dyak_GE18435|PHD finger-like domain-containing protein 5A GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0000377;GO:0006355//regulation of transcription, DNA-dependent;GO:0010557//positive regulation of macromolecule biosynthetic process 34231 3406.36 13.295 14.465 0.121682546071932 Up 0.214502707700436 CG31708 CG31708, isoform C K06774|1|7e-28|126|xla:444598|neurotrimin - - - 14462679 490.00 0.01 0.21 4.39231742277876 Up 0.216153744551578 19835795 5172.90 23.065 20.275 -0.186003377961021 Down 0.335886936996434 - CG45093, isoform D - - - - 38665 1502.98 1.07 2.285 1.09458336865692 Up 0.383998150838727 CG13288 CG13288, isoform C - - - - 41353 2004.00 17.775 18.85 0.0847149636492493 Up 0.173986263373398 CG17184 arfaptin - - - - 43019 3968.20 17.98 21.41 0.251891774871062 Up 0.392880729097873 Bili Band4.1 inhibitor LRP interactor, isoform H K06271|1|1e-06|56.6|tgu:100220667|talin GO:0043232;GO:0043232;GO:0043232;GO:0043232;GO:0043232;GO:0043232 - GO:0016055//Wnt receptor signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0016055//Wnt receptor signaling pathway;GO:0016055//Wnt receptor signaling pathway 33825 4393.86 23.855 21.685 -0.137594243121202 Down 0.274204200237749 CG9044 CG9044, isoform C K05956|1|3e-08|62.0|oaa:100087390|geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60];K05401|2|4e-07|58.2|dme:Dmel_CG5195|toll-like recepto 3;K04308|3|9e-07|57.0|oaa:100081690|leucine-rich repeat-containing G protein-coupled receptor 5;K05404|4|2e-06|55.8|rno:317468|toll-like receptor 7;K10161|5|3e-06|55.5|ptr:470827|toll-like receptor 9 - GO:0005488//binding - 33534 2715.25 9.635 11.485 0.253394285082203 Up 0.330570598335755 CG34393 CG34393, isoform B K07376|1|1e-19|99.4|mcc:696308|protein kinase, cGMP-dependent [EC:2.7.11.12] GO:0044464//cell part GO:0030695//GTPase regulator activity GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction 41724 945.00 0.375 0.285 -0.395928676331139 Down 0.0907740060758156 CG9722 CG9722 K06890|1|3e-74|278|dwi:Dwil_GK20878| - - - 117467 1579.00 0.25 0.055 -2.18442457113743 Down 0.167117950072646 mthl11 methuselah-like 11, isoform D K04599|1|2e-96|352|dpo:Dpse_GA19967|G protein-coupled receptor Mth (Methuselah protein) GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0007166//cell surface receptor signaling pathway 53434 4393.00 11.11 10.74 -0.0488648234036793 Down 0.105270109628847 c12.2 c12.2, isoform B - - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 19835398 699.00 0.12 0.01 -3.58496250072116 Down 0.14562145027077 - CG44521 - - - - 36427 1898.00 2.385 1.115 -1.09694555608521 Down 0.391394795931845 Sans sans ortholog, isoform B K06694|1|2e-08|61.2|aag:AaeL_AAEL008403|26S proteasome non-ATPase regulatory subunit 10;K08848|3|7e-08|59.3|cfa:487772|receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1];K10380|4|9e-08|58.9|hsa:287|ankyrin;K12460|5|2e-07|58.2|xtr:100145198|ankyrin repeat-rich membrane spanning protein GO:0005768//endosome;GO:0005768//endosome GO:0005488//binding;GO:0005488//binding - 32060 546.00 2.225 3.585 0.688167782848145 Up 0.370525690133404 CG15200 CG15200 - - - - 39307 2967.00 22.365 9.94 -1.16992500144231 Down 0.686897371549333 CG32091 CG32091 K05679|1|2e-87|324|tgu:100222171|ATP-binding cassette, subfamily G (WHITE), member 1;K05680|2|4e-87|323|cin:100179107|ATP-binding cassette, subfamily G (WHITE), member 4 GO:0043234//protein complex;GO:0031224//intrinsic to membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization 37017 1969.71 11.365 9.09 -0.322245484623741 Down 0.388852199181086 CG4984 CG4984, isoform D - GO:0044424//intracellular part - - 33591 325.00 135.065 65.79 -1.03771365320411 Down 0.731541408004227 CG16713 CG16713 K06238|1|3e-09|59.7|oaa:100083924|collagen, type VI, alpha;K08117|2|4e-09|59.3|tgu:100222411|amyloid beta (A4) precursor-like protein 2 - GO:0004866//endopeptidase inhibitor activity - 318653 937.00 0.045 0.28 2.63742992061529 Up 0.192048606524898 CG31269 CG31269 K11997|1|1e-41|170|ame:409206|tripartite motif-containing protein 2/3;K01312|2|4e-36|151|mcc:698352|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31564 1362.00 11.45 8.525 -0.425575859072771 Down 0.451624620261524 CG11700 CG11700 - - - - 42385 2766.00 5.45 5.72 0.0697589171141005 Up 0.100052833179237 MED25 mediator complex subunit 25 - GO:0043234//protein complex;GO:0044464//cell part - GO:0048731;GO:0006352//DNA-dependent transcription, initiation 41394 3138.00 3.13 2.95 -0.0854477026834145 Down 0.088033284902919 CG6808 CG6808, isoform B K09228|1|2e-32|141|ecb:100062031|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 33206 970.00 1.24 5.335 2.10514815043755 Up 0.62488442742042 CG11911 CG11911 K09463|1|1e-31|137|mdo:100028184|kallikrein 13 [EC:3.4.21.-];K01324|3|9e-31|134|mmu:16621|plasma kallikrein [EC:3.4.21.34];K01315|5|2e-30|133|dre:322691|plasminogen [EC:3.4.21.7] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 2769005 1292.11 4.13 6.47 0.647623930573062 Up 0.455322942808083 CG33233 CG33233, isoform E K06258|1|1e-12|48.5|ame:724429|MFS transporter, VNT family, synaptic vesicle glycoprotein 2 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0006810//transport 33817 958.00 11.14 15.57 0.483019711739005 Up 0.51367058512746 Acp26Aa accessory gland protein 26Aa - - GO:0005515//protein binding GO:0007292//female gamete generation;GO:0046662//regulation of oviposition 41359 924.75 114.9 92.305 -0.31589809462298 Down 0.538337075683529 CG17734 CG17734, isoform C - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 36392 1124.00 20.76 16.9 -0.296783197188334 Down 0.43663320565315 CG8778 CG8778 K05607|1|1e-79|296|dre:445182|methylglutaconyl-CoA hydratase [EC:4.2.1.18] GO:0015630//microtubule cytoskeleton GO:0003723//RNA binding - 38502 2115.80 71.68 82.155 0.196777743692089 Up 0.406980583806631 Teh2 tipE homolog 2, isoform B - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity - 19835042 706.00 0.175 0.255 0.543142325026529 Up 0.0890899484876502 3346145 674.00 0.01 0.135 3.75488750216347 Up 0.155263505481442 CG33557 CG33557 K09070|1|6e-20|95.9|xtr:549260|transcription factor 15 GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression 41561 990.00 100.03 75.215 -0.411340433668033 Down 0.590212653546427 CG6188 CG6188 K00552|1|5e-168|590|dme:Dmel_CG6188|glycine N-methyltransferase [EC:2.1.1.20] - - - 2768920 1144.44 2.375 0.68 -1.80432086196797 Down 0.4719653942676 squ squash, isoform C - GO:0043232 - GO:0007292//female gamete generation;GO:0003006//developmental process involved in reproduction;GO:0016458//gene silencing 19835996 1504.00 14.385 14.97 0.0575090003191295 Up 0.129540351340642 41526 777.00 28.425 26.685 -0.0911313377912941 Down 0.204728569541672 CG17202 CG17202 - - - - 43112 881.00 0.25 0.45 0.84799690655495 Up 0.144366662263902 CG17196 CG17196, isoform C - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 43533 1750.38 40.75 37.88 -0.105363728537417 Down 0.251783119799234 CG7816 Zinc/iron regulated transporter-related protein 99C, isoform J - GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport;GO:0006812//cation transport 37477 1349.08 10.315 11.17 0.11488536459683 Up 0.185576542068419 CG10307 CG10307, isoform B K12796|1|2e-22|106|xtr:780049|erbb2-interacting protein - GO:0005488//binding - 39998 2917.00 3.895 2.86 -0.44560818128328 Down 0.302403909655263 CG5290 CG5290 - - - - 35656 720.00 47.01 48.19 0.0357661205462528 Up 0.125478800686831 CG1707 CG1707 K01759|1|1e-102|372|dme:Dmel_CG1707|lactoylglutathione lyase [EC:4.4.1.5] GO:0000267//cell fraction GO:0043169//cation binding;GO:0016846//carbon-sulfur lyase activity GO:0006790//sulfur compound metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0006081//cellular aldehyde metabolic process;GO:0044238//primary metabolic process 34412 796.66 33.8 38.48 0.187085552600496 Up 0.366299035794479 mRpS7 mitochondrial ribosomal protein S7, isoform B - GO:0000314//organellar small ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0010467//gene expression 32067 1799.00 0.075 0.13 0.793549122532573 Up 0.0762779025227843 Ir10a ionotropic receptor 10a K05331|1|2e-07|57.8|tca:663613|chloride channel, invertebrate GO:0031224//intrinsic to membrane GO:0008066//glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 38631 2187.00 0.375 0.45 0.263034405833794 Up 0.0762448817857615 spo spook, isoform C K00517|1|0.0|1056|dme:Dmel_CG10594| [EC:1.14.-.-];K07408|2|4e-41|170|tgu:100230890|cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1];K07410|4|2e-39|164|mdo:100011610|cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008205//ecdysone metabolic process;GO:0048565//digestive tract development;GO:0007292//female gamete generation;GO:0001700//embryonic development via the syncytial blastoderm;GO:0007399//nervous system development 40815 855.00 61.05 56.62 -0.108679545969018 Down 0.263109232598072 twr twisted bristles roughened eye K13280|1|2e-101|368|dya:Dyak_GE24877|signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic to membrane GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0051605 318043 1243.00 2.115 2.47 0.223853378464728 Up 0.149286752080306 CG32462 CG32462 - - - - 35185 803.00 1.95 2.585 0.406690156565324 Up 0.235536917183992 CG17344 CG17344 - - - - 38944 1800.36 11.025 10.285 -0.100236861919949 Down 0.170155857878748 CG7182 CG7182, isoform B K03283|1|8e-46|185|spu:591598|heat shock 70kDa protein 1/8 - GO:0032559 - 43427 1831.00 9.64 9.585 -0.00825471456181098 Down 0.0492999603751156 Slu7 Slu7 K12819|1|0.0|875|dme:Dmel_CG1420|pre-mRNA-processing factor SLU7 - GO:0046872//metal ion binding - 12798052 721.00 0.44 0.31 -0.505235308250422 Down 0.108671245542201 38247 1485.00 1.98 0.9 -1.13750352374993 Down 0.365110289261656 CG13924 CG13924, isoform C - - - - 42854 2482.37 52.61 61.68 0.229465715180245 Up 0.432868841632545 Syx1A syntaxin 1A, isoform B K04560|1|6e-152|538|dme:Dmel_CG31136|syntaxin 1A GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0003012//muscle system process;GO:0006904//vesicle docking involved in exocytosis;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0051301//cell division;GO:0044087;GO:0035216;GO:0001505//regulation of neurotransmitter levels;GO:0003012//muscle system process;GO:0006904//vesicle docking involved in exocytosis;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0051301//cell division;GO:0044087;GO:0035216;GO:0001505//regulation of neurotransmitter levels 42280 762.00 5.61 5.7 0.0229611484433113 Up 0.0573900409457139 CG14286 CG14286 K01868|1|1e-19|96.7|nvi:100119396|threonyl-tRNA synthetase [EC:6.1.1.3] - - - 14462762 859.71 8.06 10.02 0.314030764667241 Up 0.365836745476159 CG43850 CG43850, isoform B - - - - 31857 1265.31 25.15 23.565 -0.0939127186775369 Down 0.200700039624884 CG12118 CG12118, isoform B - - - - 43438 1866.00 17.765 16.62 -0.096117306560878 Down 0.196176198652754 CG11877 Autophagy-specific gene 14 - - - - 40368 4259.75 46.47 51.445 0.146731221857853 Up 0.323702285035002 rgn regeneration, isoform D K06516|1|8e-07|57.0|mmu:16643|killer cell lectin-like receptor subfamily D, member 1;K06560|2|2e-06|55.5|gga:428421|mannose receptor, C type - - - 35897 2781.00 23.625 24.025 0.0242221016653152 Up 0.0805045568617092 CG8230 CG8230 - - - - 3772109 5682.59 29.52 18.53 -0.67182984003313 Down 0.627394003434157 Meltrin meltrin, isoform D K06835|1|3e-114|413|spu:373195|disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 19835320 683.00 1.5 2.565 0.773996325111173 Up 0.338594637432307 10178888 2132.00 2.165 2.625 0.27795039782676 Up 0.1828028001585 pre-mod(mdg4)-AD pre-mod(mdg4)-AD - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 39572 3086.71 61.815 59.175 -0.0629691633796785 Down 0.171311583674548 nuf nuclear fallout, isoform M K12485|1|0.0|686|dan:Dana_GF24596|Rab11 family-interacting protein 3/4 GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane GO:0016740//transferase activity;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0015631//tubulin binding GO:0006810//transport;GO:0001709//cell fate determination;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006497//protein lipidation;GO:0006810//transport;GO:0001709//cell fate determination;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006497//protein lipidation;GO:0006810//transport;GO:0001709//cell fate determination;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006497//protein lipidation;GO:0006810//transport;GO:0001709//cell fate determination;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006497//protein lipidation;GO:0006810//transport;GO:0001709//cell fate determination;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006497//protein lipidation;GO:0006810//transport;GO:0001709//cell fate determination;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0006497//protein lipidation 3772392 192.00 23.385 2.75 -3.08807990500692 Down 0.788138951261392 41376 2101.09 10.815 13.005 0.266032733981012 Up 0.360124157971206 CG17230 CG17230, isoform C - - - - 43069 3121.88 5.785 6.555 0.180278821114264 Up 0.210837405890899 CG10669 CG10669, isoform B K09228|1|2e-107|390|dpo:Dpse_GA11270|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 34906 2222.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 wor worniu K09218|1|0.0|1016|dme:Dmel_CG4158|snail, invertebrate GO:0044464//cell part GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0007417//central nervous system development;GO:0010468//regulation of gene expression;GO:0045165//cell fate commitment;GO:0048812//neuron projection morphogenesis 12797872 298.00 0.155 0.37 1.25525705524207 Up 0.163650772685246 CG43348 CG43348, isoform B - - - - 34608 3178.60 22.055 22.935 0.0564451469897436 Up 0.145093118478404 CG6686 CG6686, isoform C K11984|1|0.0|1252|dme:Dmel_CG6686|U4/U6.U5 tri-snRNP-associated protein 1 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - - 40616 4998.16 32.445 23.24 -0.481386097278606 Down 0.577862897899881 corto corto, isoform E - GO:0031519//PcG protein complex;GO:0005694//chromosome GO:0042802//identical protein binding - 42694 1757.00 1.04 0.565 -0.880260755725904 Down 0.235041606128649 CG6985 CG6985 K10877|1|8e-13|75.5|cqu:CpipJ_CPIJ002331|DNA repair and recombination protein RAD54B [EC:3.6.1.-] - - - 42907 921.00 3.705 5.075 0.453934279766704 Up 0.345991282525426 CG5762 CG5762 - - - - 43420 2274.00 77.16 64.54 -0.257659565562162 Down 0.470248315942412 CG1443 waterproof K13356|1|3e-116|419|api:100166286|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 38206 3206.17 143.44 190.49 0.409267870388742 Up 0.601274600449082 CG7971 CG7971, isoform H K13172|1|6e-57|221|dme:Dmel_CG7971|serine/arginine repetitive matrix protein 2 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - GO:0000377;GO:0000377 33524 8530.53 161.575 154.815 -0.0616587308750607 Down 0.179071456874917 CG3523 CG3523, isoform C K00665|1|0.0|4845|dme:Dmel_CG3523|fatty acid synthase, animal type [EC:2.3.1.85] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0022892;GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0022892 GO:0008152//metabolic process;GO:0008152//metabolic process 36808 1977.00 11.15 12.945 0.215351255092444 Up 0.314852727512878 fidipidine fidipidine K11498|1|2e-06|54.3|ptr:461413|centromeric protein E - - - 39989 2330.43 12.93 14.88 0.202652251297777 Up 0.312310130762119 CG7441 CG7441, isoform B K01867|1|0.0|1139|dme:Dmel_CG7441|tryptophanyl-tRNA synthetase [EC:6.1.1.2] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 47854 1319.00 7.285 11.97 0.716422274878989 Up 0.561583674547616 Mst98Ca Male-specific RNA 98Ca - - - - 8674119 575.96 2.68 4.285 0.677062203654728 Up 0.396744155329547 CG42550 kinetochore Mis12-Ndc80 network component 2, isoform D K03858|1|5e-20|96.3|dme:Dmel_CG14463|phosphatidylinositol glycan, class H - - - 317856 3892.00 0.185 0.435 1.23349013021978 Up 0.17388720116233 CG32107 CG32107, isoform E - - - - 12797906 740.11 0.12 1.4 3.54432051622381 Up 0.467903843613789 39670 1191.00 148.425 102.845 -0.529262456828079 Down 0.646645093118478 CG7272 CG7272 - GO:0031224//intrinsic to membrane - - 33974 3634.00 12.35 12.07 -0.0330853657170184 Down 0.0846321489895654 SA stromalin K06671|1|0.0|2083|dme:Dmel_CG3423|cohesin complex subunit SA-1/2 GO:0043234//protein complex;GO:0000794//condensed nuclear chromosome;GO:0031981//nuclear lumen;GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0044430//cytoskeletal part - GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0007140//male meiosis 41040 1328.00 3.39 4.3 0.343051386453117 Up 0.271133271694624 CG8159 CG8159 K09228|1|5e-31|135|mmu:24132|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 33834 1230.27 174.62 206.765 0.243773188464076 Up 0.468762382776384 chic chickadee, isoform F K05759|1|1e-67|257|dme:Dmel_CG9553|profilin GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton GO:0035091//phosphatidylinositol binding;GO:0008092//cytoskeletal protein binding;GO:0035091//phosphatidylinositol binding;GO:0008092//cytoskeletal protein binding;GO:0035091//phosphatidylinositol binding;GO:0008092//cytoskeletal protein binding;GO:0035091//phosphatidylinositol binding;GO:0008092//cytoskeletal protein binding GO:0032989;GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0051276//chromosome organization;GO:0045185//maintenance of protein location;GO:0019094//pole plasm mRNA localization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0006935//chemotaxis;GO:0048232//male gamete generation;GO:0007560//imaginal disc morphogenesis;GO:0032989;GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0051276//chromosome organization;GO:0045185//maintenance of protein location;GO:0019094//pole plasm mRNA localization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0006935//chemotaxis;GO:0048232//male gamete generation;GO:0007560//imaginal disc morphogenesis;GO:0032989;GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0051276//chromosome organization;GO:0045185//maintenance of protein location;GO:0019094//pole plasm mRNA localization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0006935//chemotaxis;GO:0048232//male gamete generation;GO:0007560//imaginal disc morphogenesis;GO:0032989;GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0051276//chromosome organization;GO:0045185//maintenance of protein location;GO:0019094//pole plasm mRNA localization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0000912//assembly of actomyosin apparatus involved in cell cycle cytokinesis;GO:0006935//chemotaxis;GO:0048232//male gamete generation;GO:0007560//imaginal disc morphogenesis 38774 1004.00 0.08 0.18 1.16992500144231 Up 0.108076872275789 Cpr65Eb cuticular protein 65Eb - - GO:0005198//structural molecule activity - 10178831 564.00 33.36 29.975 -0.154359535143078 Down 0.308875974111742 CG42846 CG42846 - - - - 43037 1039.00 0.43 0.715 0.733606582076292 Up 0.171410645885616 CG11854 CG11854 K12347|1|8e-09|61.2|dan:Dana_GF18523|natural resistance-associated macrophage protein - - - 252554 2235.00 7.37 6.21 -0.247071350874588 Down 0.276053361511029 sav salvador, isoform B K05629|1|2e-07|57.8|bfo:BRAFLDRAFT_203488|atrophin-1 interacting protein 1;K05633|2|4e-07|57.0|oaa:100075459|atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:6.3.2.19];K05632|3|9e-07|55.8|mdo:100032356|atrophin-1 interacting protein 4 [EC:6.3.2.19] - GO:0005488//binding;GO:0005488//binding GO:0023060;GO:0023060 40016 1382.00 6.64 6.335 -0.0678386222061155 Down 0.106557918372738 skl sickle - - - GO:0012502//induction of programmed cell death 19835321 985.00 15.205 18.555 0.287262184666728 Up 0.416985867124554 35418 1587.39 108.055 80.61 -0.422735103997353 Down 0.597345132743363 Df31 decondensation factor 31, isoform F - GO:0044427//chromosomal part;GO:0044427//chromosomal part;GO:0044427//chromosomal part - GO:0034728//nucleosome organization;GO:0034728//nucleosome organization;GO:0034728//nucleosome organization 12798059 444.00 1.555 0.59 -1.39812772076876 Down 0.358043851538766 35749 2721.69 27.535 24.305 -0.180013474362297 Down 0.336217144366662 CG14764 CG14764, isoform C - - - - 12797867 2230.00 1.155 1.295 0.165059246270496 Up 0.0919627526086382 8674112 1353.00 0.09 0.23 1.3536369546147 Up 0.129573372077665 CG42617 CG42617 - - - - 34726 1020.00 1.175 1.545 0.394946081339375 Up 0.176495839387135 Prosalpha6T proteasome alpha6 subunit, Testis-specific K02725|1|1e-167|588|dme:Dmel_CG5648|20S proteasome subunit alpha 6 [EC:3.4.25.1] GO:0015630//microtubule cytoskeleton;GO:0043073//germ cell nucleus;GO:0044444//cytoplasmic part;GO:0005839//proteasome core complex GO:0004175//endopeptidase activity GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0006997//nucleus organization;GO:0003006//developmental process involved in reproduction 33335 1421.00 0.2 0.405 1.01792190799726 Up 0.151334037775723 Or22a odorant receptor 22a K08471|1|0.0|810|dme:Dmel_CG12193|gustatory receptor GO:0043005//neuron projection;GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 19835341 990.00 0.08 0.11 0.459431618637297 Up 0.0617157574957073 34527 5157.94 5.13 4.89 -0.0691243606548203 Down 0.0944062871483291 Nup154 nucleoporin 154kD, isoform D - GO:0005635//nuclear envelope;GO:0005635//nuclear envelope GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity GO:0051169//nuclear transport;GO:0051169//nuclear transport 10178892 559.00 63.83 53.915 -0.243547938545399 Down 0.44554880464932 59177 865.00 0.01 0.555 5.79441586635011 Up 0.38171971998415 Tsp42Eb tetraspanin 42Eb K06497|1|2e-128|457|dme:Dmel_CG30160|CD63 antigen GO:0031224//intrinsic to membrane - - 31275 1345.00 0.06 0.045 -0.415037499278844 Down 0.0547483819838859 CG14418 CG14418, isoform B - - - - 31817 1533.41 7.725 6.6 -0.227068908545921 Down 0.266081098930128 CG1885 CG1885, isoform B K01719|1|7e-158|556|dme:Dmel_CG1885|uroporphyrinogen-III synthase [EC:4.2.1.75] - GO:0005488//binding;GO:0016836//hydro-lyase activity GO:0018130 34428 1050.00 6.6 7.045 0.0941336820638208 Up 0.133932109364681 CG5188 CG5188 K01265|1|1e-176|619|dme:Dmel_CG5188|methionyl aminopeptidase [EC:3.4.11.18] - GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process 31576 1892.98 38.955 30.115 -0.371326255816571 Down 0.534803856822084 CG3842 CG3842, isoform D K00100|1|7e-74|278|dme:Dmel_CG2070| [EC:1.1.1.-];K11153|2|7e-64|244|rno:314264|retinol dehydrogenase 12 [EC:1.1.1.-];K11162|3|9e-64|244|xtr:549985|retinol dehydrogenase 14 [EC:1.1.1.-] - - - 43864 784.54 1221.615 1256.725 0.0408793078613422 Up 0.140470215295205 RpL10 ribosomal protein L10, isoform E K02866|1|2e-117|421|dme:Dmel_CG17521|large subunit ribosomal protein L10e GO:0044297//cell body;GO:0015934//large ribosomal subunit;GO:0044297//cell body;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0004659//prenyltransferase activity;GO:0005198//structural molecule activity;GO:0004659//prenyltransferase activity GO:0007276//gamete generation;GO:0007052//mitotic spindle organization;GO:0006720//isoprenoid metabolic process;GO:0010467//gene expression;GO:0009790//embryo development;GO:0007276//gamete generation;GO:0007052//mitotic spindle organization;GO:0006720//isoprenoid metabolic process;GO:0010467//gene expression;GO:0009790//embryo development 19836091 451.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 19834964 2486.00 289.905 213.98 -0.438104256804111 Down 0.620492669396381 - CG45087 - - - - 37925 3268.98 16.4 14.75 -0.15298086036888 Down 0.263406419231277 Fcp1 Fcp1, isoform B K01090|1|3e-109|397|dre:442930|protein phosphatase [EC:3.1.3.16] GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle GO:0016791//phosphatase activity - 41588 707.00 0.285 0.69 1.27563444261343 Up 0.228371417250033 CG14384 CG14384, isoform B - - - - 38781 352.00 0.125 0.01 -3.64385618977472 Down 0.151697265882974 CG8629 CG8629 K08762|1|3e-19|93.2|xla:444376|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) - GO:0008144//drug binding;GO:0030234//enzyme regulator activity;GO:0005504//fatty acid binding GO:0055082//cellular chemical homeostasis 36293 1708.00 5.175 6.47 0.32220684960582 Up 0.315612204464404 CG8888 CG8888 K00019|1|1e-48|194|bfo:BRAFLDRAFT_290938|3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] - GO:0003824//catalytic activity GO:0008152//metabolic process 33754 1666.00 27.18 35.385 0.380592463193228 Up 0.534671773873993 Cyp4ac1 Cyp4ac1 K00517|1|0.0|993|dme:Dmel_CG14032| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0009407//toxin catabolic process 5740178 686.00 0.63 0.39 -0.691877704637668 Down 0.151135913353586 CG34286 CG34286, isoform B - - - - 38754 1430.00 0.455 0.3 -0.600904044590177 Down 0.117256637168142 CG14820 CG14820 K01290|1|2e-99|362|dmo:Dmoj_GI16514|carboxypeptidase A, invertebrate [EC:3.4.17.-] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 35795 1908.00 25.06 23.57 -0.0884346560716932 Down 0.197926297714965 CG2183 GASZ ortholog K12460|1|2e-14|80.9|mdo:100032130|ankyrin repeat-rich membrane spanning protein - - - 44669 4766.19 13.68 14.31 0.0649554418407698 Up 0.133403777572315 cwo clockwork orange, isoform C K09091|1|5e-34|147|ame:726204|hairy and enhancer of split related with YRPW motif GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 35397 8850.97 11.79 14.225 0.270864934214182 Up 0.373101307621186 CG8677 CG8677, isoform C K11657|1|0.0|3774|dme:Dmel_CG8677|remodeling and spacing factor 1 - GO:0005488//binding - 39260 2116.66 5.31 5.61 0.0792889098046388 Up 0.108109893012812 CG7616 CG7616, isoform B K08869|1|0.0|1100|dme:Dmel_CG7616|aarF domain-containing kinase - - - 39278 1356.00 1.15 1.5 0.383328639551505 Up 0.171047417778365 CG7557 CG7557, isoform B - - - - 41009 2018.19 21.43 19.57 -0.130988094049744 Down 0.255547483819839 CG11737 CG11737, isoform C K02354|1|6e-30|132|spu:583340|frizzled 4 - - - 41945 2879.00 0.015 0.05 1.73696559416621 Up 0.0670320961563862 GATAe GATAe, isoform C K09183|1|1e-23|112|spu:408052|GATA-binding protein 4/5/6;K09182|3|1e-23|112|dre:30458|GATA-binding protein 1/2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0009888//tissue development;GO:0006959//humoral immune response;GO:0009888//tissue development;GO:0006959//humoral immune response 318668 1020.91 0.205 0.355 0.792195114886598 Up 0.12303526614714 CG31296 CG31296, isoform B - - - - 12798393 573.52 0.405 0.425 0.069540933253077 Up 0.045898824461762 CG43171 CG43171, isoform B - - - - 48532 1082.00 0.465 0.4 -0.217230716220669 Down 0.069937921014397 PpY-55A protein phosphatase Y at 55A, isoform B K01090|1|0.0|655|dme:Dmel_CG10930|protein phosphatase [EC:3.1.3.16];K06269|2|3e-112|405|mcc:709935|protein phosphatase 1, catalytic subunit [EC:3.1.3.16] GO:0035097//histone methyltransferase complex;GO:0031966//mitochondrial membrane;GO:0030425//dendrite;GO:0000776//kinetochore GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0005975//carbohydrate metabolic process;GO:0032386//regulation of intracellular transport;GO:0006464//cellular protein modification process 37519 2650.30 106.35 83.87 -0.342593272121647 Down 0.551974640073966 CG11073 CG11073, isoform E - - - - 43999 2372.00 8.96 6.81 -0.395843934045533 Down 0.402357680623432 trbl tribbles K08814|1|0.0|879|dme:Dmel_CG5408|tribbles [EC:2.7.11.-] GO:0044424//intracellular part GO:0055103//ligase regulator activity;GO:0004672//protein kinase activity;GO:0032559;GO:0019899//enzyme binding GO:0032270//positive regulation of cellular protein metabolic process;GO:0010004//gastrulation involving germ band extension;GO:0045596//negative regulation of cell differentiation;GO:0007088//regulation of mitosis;GO:0044092//negative regulation of molecular function;GO:0042325//regulation of phosphorylation;GO:0050790//regulation of catalytic activity;GO:0031331;GO:0006464//cellular protein modification process;GO:0042036//negative regulation of cytokine biosynthetic process 34303 1090.00 2.76 2.92 0.0813001021018482 Up 0.0821886144498745 CG13123 CG13123, isoform C K09216|1|6e-08|58.5|xtr:448478|ovo GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 36444 4320.67 45.675 28.44 -0.683483263895436 Down 0.651895390305112 TppII tripeptidyl-peptidase II, isoform F K01280|1|0.0|2582|dme:Dmel_CG3991|tripeptidyl-peptidase II [EC:3.4.14.10] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity;GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity GO:0051259//protein oligomerization;GO:0019538//protein metabolic process;GO:0051259//protein oligomerization;GO:0019538//protein metabolic process 35402 4011.06 28.14 26.07 -0.110231745700976 Down 0.237848368775591 Mio Mlx interactor, isoform M K09113|1|0.0|1754|dme:Dmel_CG18362|MAX-like protein X GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction;GO:0001709//cell fate determination;GO:0006281//DNA repair;GO:0007126//meiosis;GO:0044267//cellular protein metabolic process;GO:0010468//regulation of gene expression;GO:0003006//developmental process involved in reproduction 43493 2354.00 108.99 124.075 0.187016683047842 Up 0.403183199049003 Gycalpha99B guanylyl cyclase alpha-subunit at 99B K12318|1|0.0|1367|dme:Dmel_CG1912|guanylate cyclase soluble subunit alpha [EC:4.6.1.2] GO:0043234//protein complex;GO:0044424//intracellular part GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0005506//iron ion binding GO:0007603//phototransduction, visible light;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0042331//phototaxis 43997 7024.14 47.51 47.42 -0.00273554392883601 Down 0.0451393475102364 jbug jitterbug, isoform N K04437|1|0.0|816|dme:Dmel_CG30092|filamin - GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0009605//response to external stimulus;GO:0009605//response to external stimulus;GO:0009605//response to external stimulus;GO:0009605//response to external stimulus;GO:0009605//response to external stimulus;GO:0009605//response to external stimulus;GO:0009605//response to external stimulus 39105 709.00 0.87 1.315 0.595975493443574 Up 0.20667679302602 CG32036 CG32036 - - GO:0030247//polysaccharide binding GO:0006022 42770 1892.85 65.64 54.64 -0.264617755223622 Down 0.466120723814556 Irk2 inwardly rectifying potassium channel 2, isoform D K05002|1|3e-92|338|rno:116560|potassium inwardly-rectifying channel subfamily J member 9 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005249//voltage-gated potassium channel activity;GO:0016301//kinase activity;GO:0032559;GO:0005249//voltage-gated potassium channel activity;GO:0016301//kinase activity;GO:0032559;GO:0005249//voltage-gated potassium channel activity;GO:0016301//kinase activity;GO:0032559 GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process 32705 814.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 CG5070 CG5070 - - - - 37543 2163.00 0.265 0.1 -1.40599235967584 Down 0.140173028662 Oatp58Da organic anion transporting polypeptide 58Da - GO:0044464//cell part - GO:0006820//anion transport 34326 845.00 9.94 10.265 0.0464158705463157 Up 0.0997556465460309 CG5846 CG5846 K08062|1|4e-24|111|dre:100170804|regulatory factor X-associated ankyrin-containing protein - - - 35609 3467.21 11.55 11.15 -0.0508491414957529 Down 0.108208955223881 vimar visceral mesodermal armadillo-repeats, isoform C - - - GO:0009060//aerobic respiration;GO:0009060//aerobic respiration 38074 2198.00 27.465 24.26 -0.179014741397983 Down 0.336019019944525 CG13893 CG13893 - GO:0044464//cell part - GO:0051234//establishment of localization 40824 834.00 18.85 77.64 2.04223559455764 Up 0.779850746268657 Ccp84Ab Ccp84Ab - - GO:0042302//structural constituent of cuticle - 37744 738.03 88.59 72.105 -0.297044552996059 Down 0.515321621978603 l(2)efl lethal (2) essential for life, isoform C K09542|1|2e-104|378|dme:Dmel_CG4533|crystallin, alpha B;K09541|5|5e-28|124|gga:418546|crystallin, alpha A - GO:0005198//structural molecule activity GO:0006950//response to stress 53560 8421.63 21.195 23.96 0.17690394173369 Up 0.326740192841104 cic capicua, isoform H K09267|1|8e-12|73.9|dmo:Dmoj_GI11538|transcription factor SOX1/2/3/14/21 (SOX group B) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0008134//transcription factor binding;GO:0030528//transcription regulator activity;GO:0008134//transcription factor binding GO:0006351//transcription, DNA-dependent;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0003006//developmental process involved in reproduction;GO:0009792//embryo development ending in birth or egg hatching;GO:0009887//organ morphogenesis;GO:0016049//cell growth;GO:0006351//transcription, DNA-dependent;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0003006//developmental process involved in reproduction;GO:0009792//embryo development ending in birth or egg hatching;GO:0009887//organ morphogenesis;GO:0016049//cell growth 36693 3361.00 0.225 0.085 -1.40439025507934 Down 0.130002641658962 alphaPS4 integrin alphaPS4 subunit K06584|1|5e-69|263|mdo:100027090|integrin alpha 8;K06487|2|3e-67|257|dre:100151255|integrin alpha V GO:0005887//integral to plasma membrane GO:0004872//receptor activity;GO:0005515//protein binding GO:0048565//digestive tract development;GO:0016337//cell-cell adhesion;GO:0007613//memory;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0006935//chemotaxis;GO:0007160//cell-matrix adhesion;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0007166//cell surface receptor signaling pathway 38127 480.00 26.295 0.115 -7.83701082542368 Down 0.940430590410778 LysD lysozyme D K01183|1|2e-80|296|dme:Dmel_CG9118|chitinase [EC:3.2.1.14];K01185|1|2e-80|296|dme:Dmel_CG9118|lysozyme [EC:3.2.1.17];K13915|5|1e-73|274|dpe:Dper_GL16156|lysozyme C [EC:3.2.1.17] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds GO:0006959//humoral immune response;GO:0009056//catabolic process 41297 740.00 217.15 209.39 -0.0524994087795453 Down 0.158763703605864 CG14687 CG14687 K00907|1|2e-06|52.8|bfo:BRAFLDRAFT_69337|myosin-light-chain kinase [EC:2.7.11.18] - - - 35975 2240.00 0.705 0.68 -0.0520885111484544 Down 0.0483423590014529 Wnt2 Wnt oncogene analog 2, isoform B K00572|1|0.0|654|dan:Dana_GF12469|wingless-type MMTV integration site family, member 7 GO:0031012//extracellular matrix GO:0060089;GO:0005515//protein binding GO:0060541//respiratory system development;GO:0048588//developmental cell growth;GO:0048513//organ development;GO:0035567//non-canonical Wnt receptor signaling pathway 37766 1078.00 1.715 2.235 0.382066255010506 Up 0.20991282525426 CG5539 CG5539, isoform B K11449|1|1e-16|87.0|cfa:474695|jumonji domain-containing protein 1 [EC:1.14.11.-] - - - 7354376 1540.00 8.12 10.95 0.43137923730336 Up 0.447397965922599 tal-2A tal-2A - - - - 5740242 450.00 0.095 0.01 -3.24792751344359 Down 0.120756835292564 CG34185 CG34185 - - - - 318879 1151.00 5.875 4.35 -0.433573450716272 Down 0.358638224805178 CG31675 CG31675 - - - - 35514 1280.00 0.15 0.205 0.450661409009565 Up 0.0739334301941619 Or42a odorant receptor 42a K08471|1|0.0|786|dme:Dmel_CG17250|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 31401 2292.00 0.205 0.655 1.67587099691937 Up 0.252707700435874 CG15473 CG15473 - - - - 19835679 573.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 47611 2469.21 116.43 98.045 -0.247946874657425 Down 0.470215295205389 Gpo-1 glycerophosphate oxidase-1, isoform D K00111|1|0.0|1430|dme:Dmel_CG8256|glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0046872//metal ion binding;GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0046872//metal ion binding;GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0046872//metal ion binding;GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0046872//metal ion binding GO:0006071//glycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0022904//respiratory electron transport chain;GO:0006071//glycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0022904//respiratory electron transport chain;GO:0006071//glycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0022904//respiratory electron transport chain;GO:0006071//glycerol metabolic process;GO:0008344//adult locomotory behavior;GO:0022904//respiratory electron transport chain 3772504 639.00 0.07 0.075 0.0995356735509144 Up 0.0433232069739797 CG33630 CG33630 - - - - 38433 4200.41 33.15 36.845 0.15245998332089 Up 0.312970545502576 Eip63E Ecdysone-induced protein 63E, isoform N K08820|1|0.0|944|dme:Dmel_CG10579|PCTAIRE protein kinase [EC:2.7.11.22] - GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development;GO:0009792//embryo development ending in birth or egg hatching;GO:0006464//cellular protein modification process;GO:0048729//tissue morphogenesis;GO:0040007//growth;GO:0002164//larval development 39093 2117.72 35.685 33.995 -0.0699952027582571 Down 0.177123233390569 CG3529 CG3529, isoform D K12404|1|1e-22|108|xla:444026|ADP-ribosylation factor-binding protein GGA;K04705|4|4e-21|103|phu:Phum_PHUM584200|signal transducing adaptor molecule;K12182|5|8e-21|102|spu:578315|hepatocyte growth factor-regulated tyrosine kinase substrate GO:0044464//cell part - GO:0015031//protein transport 41075 2429.75 22.77 14.59 -0.642154408218732 Down 0.604048342359001 CG31100 CG31100, isoform B K08145|1|2e-28|128|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8;K08144|3|2e-23|111|xla:447505|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6 GO:0031224//intrinsic to membrane - GO:0006810//transport 43658 1267.00 2.22 1.945 -0.190789521363914 Down 0.126766609430722 CG15545 CG15545 - - - - 31980 2356.84 38.225 34.175 -0.161575163754745 Down 0.327466649055607 CG32687 CG32687, isoform B K01768|1|3e-15|84.0|dme:Dmel_CG10255|adenylate cyclase [EC:4.6.1.1] - GO:0005488//binding - 39309 2068.94 4.545 4.845 0.0922163712209742 Up 0.111180821555937 CG11660 RIO kinase 1, isoform B K07178|1|0.0|957|dme:Dmel_CG11660|RIO kinase 1 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 - 35053 2458.00 85.22 94.06 0.142389280679762 Up 0.325056135252939 Aac11 Aac11 - GO:0043231//intracellular membrane-bounded organelle GO:0019838//growth factor binding GO:0043066//negative regulation of apoptotic process 12798389 2813.00 0.115 0.02 -2.52356195605701 Down 0.113261127988377 42799 1532.00 1.09 0.765 -0.510796482084275 Down 0.173523973055079 nau nautilus, isoform B K09064|1|6e-31|135|spu:373197|myogenic factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0014706//striated muscle tissue development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048513//organ development;GO:0014706//striated muscle tissue development;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0048513//organ development 19836115 824.00 0.21 0.31 0.561878887608115 Up 0.09708096684718 39878 7520.17 147.94 163.135 0.141054159148874 Up 0.332849029190332 CG9674 CG9674, isoform I K00264|1|0.0|4078|dme:Dmel_CG9674|glutamate synthase (NADPH/NADH) [EC:1.4.1.13 1.4.1.14] - GO:0030554//adenyl nucleotide binding;GO:0046914//transition metal ion binding;GO:0051540;GO:0015930//glutamate synthase activity;GO:0030554//adenyl nucleotide binding;GO:0046914//transition metal ion binding;GO:0051540;GO:0015930//glutamate synthase activity GO:0006536//glutamate metabolic process;GO:0006536//glutamate metabolic process 40425 890.00 0.78 1.355 0.796746822491623 Up 0.251089684321754 CG14564 CG14564 - - - - 40835 4630.27 1.18 1.015 -0.217307132176665 Down 0.103817197199842 Antp antennapedia, isoform N K09311|1|1e-103|378|dsi:Dsim_GD19515|Antp family, other GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-dependent;GO:0014016//neuroblast differentiation;GO:0048534;GO:0009798//axis specification;GO:0007380//specification of segmental identity, head;GO:0035292//specification of segmental identity, trunk 43098 3005.00 1.355 1.665 0.297229325717391 Up 0.153216219786026 Lgr3 Leucine-rich repeat-containing G protein-coupled receptor 3 K04307|1|0.0|1446|dme:Dmel_CG31096|leucine-rich repeat-containing G protein-coupled receptor 8;K04306|2|3e-104|380|bfo:BRAFLDRAFT_134702|leucine-rich repeat-containing G protein-coupled receptor 7 GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0050794//regulation of cellular process 14462858 402.00 0.53 0.125 -2.08406426478847 Down 0.245905428609167 2768915 800.00 0.345 1.37 1.98950762618236 Up 0.383998150838727 CG33306 CG33306 - - - - 41533 1355.00 23.21 24.235 0.0623455598219176 Up 0.150475498613129 CG5844 CG5844 K01692|1|7e-83|307|aga:AgaP_AGAP001715|enoyl-CoA hydratase [EC:4.2.1.17] - - - 35646 1495.00 8.155 7.29 -0.161766062384947 Down 0.213346981904636 Gadd45 Gadd45 K04402|1|1e-82|307|dme:Dmel_CG11086|growth arrest and DNA-damage-inducible protein GO:0043231//intracellular membrane-bounded organelle - - 14462702 807.00 10.945 12.34 0.173070439968472 Up 0.263274336283186 36514 2793.00 8.885 8.8 -0.0138682525040184 Down 0.0526350548144235 CG6197 fand K12867|1|0.0|1674|dme:Dmel_CG6197|pre-mRNA-splicing factor SYF1 GO:0005681//spliceosomal complex - GO:0006909//phagocytosis;GO:0000380//alternative mRNA splicing, via spliceosome 39938 2980.00 0.375 0.705 0.910732661902913 Up 0.19346849821688 CG13731 CG13731 - - - - 34890 1782.18 0.375 0.815 1.1199094637352 Up 0.234050984017963 ZnT35C zinc transporter 35C, isoform B K03295|1|5e-58|225|mmu:22785|cation efflux system protein, CDF family GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity GO:0010038//response to metal ion;GO:0006811//ion transport;GO:0010038//response to metal ion;GO:0006811//ion transport 33480 1066.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 Cpr23B cuticular protein 23B - - GO:0005198//structural molecule activity - 32282 1733.54 9.345 10.6 0.181797695705404 Up 0.259774138158764 CG1622 CG1622, isoform C K12850|1|8e-106|384|dme:Dmel_CG1622|pre-mRNA-splicing factor 38B - - - 49701 3976.19 57.2 66.035 0.207215740232812 Up 0.412561088363492 gish gilgamesh, isoform M K02218|1|0.0|900|dme:Dmel_CG6963|casein kinase 1 [EC:2.7.11.1];K08958|2|0.0|899|der:Dere_GG16991|casein kinase 1, gamma [EC:2.7.11.1] GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway;GO:0016477//cell migration;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway 32542 1422.00 2.5 2.26 -0.145605322246899 Down 0.113657376832651 CG15914 CG15914 - - - GO:0008152//metabolic process 41626 1269.00 6.805 7.625 0.164142175833616 Up 0.209021265354643 Ravus ravus - - - - 53547 792.00 4.75 4.865 0.0345122915628013 Up 0.0651829348831066 lectin-29Ca lectin-29Ca K05328|1|4e-12|71.6|dan:Dana_GF15877|transient receptor potential cation channel subfamily C, invertebrate;K06560|2|5e-08|58.2|bfo:BRAFLDRAFT_80311|mannose receptor, C type - - - 37223 3076.00 9.5 6.28 -0.597162954326683 Down 0.497193237353058 CG9416 CG9416, isoform B - - - - 50381 349.00 33.74 32.56 -0.0513592740213187 Down 0.140338132347114 mRpL33 mitochondrial ribosomal protein L33 - GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 40884 1107.00 0.215 0.39 0.85913746416015 Up 0.137267203803989 nxf4 nuclear export factor 4 - - GO:0005488//binding - 41454 1187.00 19.605 37.87 0.94983377936783 Up 0.688152159556201 CG3397 CG3397 K04882|1|7e-10|65.1|dre:541540|potassium voltage-gated channel Shaker-related subfamily A, beta member 1;K04883|3|6e-09|62.0|dre:797337|potassium voltage-gated channel Shaker-related subfamily A, beta member 2 - GO:0003824//catalytic activity GO:0030001//metal ion transport;GO:0008152//metabolic process 32591 3215.00 4.27 4.43 0.053070628934528 Up 0.0768722757891956 CG3679 CG3679, isoform B - - - - 36530 1222.24 0.425 0.6 0.497499659470817 Up 0.122639017302866 CG6337 CG6337, isoform B K01365|1|6e-18|91.7|spu:575142|cathepsin L [EC:3.4.22.15];K01371|3|2e-14|80.1|dme:Dmel_CG4847|cathepsin K [EC:3.4.22.38] - GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process 32984 2053.00 4.875 4.5 -0.115477217419936 Down 0.135385021793686 CG14230 CG14230 - - GO:0005488//binding - 45329 666.61 837.645 745.24 -0.168633837325837 Down 0.389446572447497 RpL12 ribosomal protein L12, isoform C K02870|1|4e-90|330|dya:Dyak_GE14368|large subunit ribosomal protein L12e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0010467//gene expression 19835301 239.00 0.01 0.23 4.52356195605701 Up 0.229362039360719 12798298 542.00 0.975 0.255 -1.93490497177812 Down 0.327631752740721 CG43321 CG43321 - - - - 41715 1206.00 0.01 0.25 4.64385618977472 Up 0.24085325584467 Or88a odorant receptor 88a K08471|1|0.0|808|dme:Dmel_CG14360|gustatory receptor - - - 32609 3518.00 0.075 0.075 -3.20342650381492e-16 Down 0.0382380134724607 CG9981 CG9981, isoform C K01530|1|0.0|1404|dwi:Dwil_GK25709|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0032559 GO:0009206;GO:0006869//lipid transport 39908 2123.00 0.905 0.595 -0.605028123775262 Down 0.172170122837142 CG7730 CG7730 - - - - 34195 2129.00 0.055 0.09 0.710493382805015 Up 0.06244221371021 CG9289 CG9289 K01063|1|9e-46|185|dme:Dmel_CG8425|juvenile-hormone esterase [EC:3.1.1.59];K03927|2|2e-43|177|api:100168834|carboxylesterase type B [EC:3.1.1.1];K01044|4|2e-41|170|mdo:100020705|carboxylesterase [EC:3.1.1.1] - - - 14462723 282.00 1.145 3.395 1.56806397614779 Up 0.5122837141725 3772423 798.00 0.105 0.23 1.13124453327825 Up 0.11781798969753 CG33673 CG33673 K06890|1|2e-25|115|dwi:Dwil_GK20878| GO:0031224//intrinsic to membrane - - 31500 2312.86 50.625 48.26 -0.0690220873309605 Down 0.184684982168802 CG15771 CG15771, isoform D K07025|1|6e-153|541|dse:Dsec_GM12434|putative hydrolase of the HAD superfamily - - - 40432 1594.00 14.575 14.03 -0.0549808744679597 Down 0.118709549597147 CG7148 CG7148 - - - - 3354992 2238.05 50.15 48.76 -0.040551574879331 Down 0.127559107119271 CG2893 zydeco, isoform H K13751|1|2e-51|203|mmu:94249|solute carrier family 24 (sodium/potassium/calcium exchanger), member 3;K13752|3|4e-51|202|bta:615739|solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0015368//calcium:cation antiporter activity GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport 319042 699.04 1.545 1.715 0.150601738268438 Up 0.0977744023246599 CG31949 CG31949, isoform B - - - - 3772432 2080.00 34.02 25.325 -0.425820871974884 Down 0.557819310527011 Adhr Adh-related, isoform C K00001|1|6e-144|511|dme:Dmel_CG3481|alcohol dehydrogenase [EC:1.1.1.1] GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process;GO:0006067//ethanol metabolic process;GO:0030534//adult behavior;GO:0006081//cellular aldehyde metabolic process 39600 555.00 0.15 0.18 0.263034405833794 Up 0.0589420155857879 CG13474 CG13474 - - - - 42626 1293.80 16.42 13.02 -0.33472467861217 Down 0.43917580240391 CG7059 CG7059, isoform D K01834|1|2e-52|206|mdo:100025819|phosphoglycerate mutase [EC:5.4.2.1] - GO:0016866//intramolecular transferase activity;GO:0016866//intramolecular transferase activity;GO:0016866//intramolecular transferase activity GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process 39116 1026.00 2.345 4.07 0.795440871750871 Up 0.422104081363096 CG3306 CG3306 - - - - 37293 5102.00 0.415 0.46 0.148522524710088 Up 0.0594703473781535 CG8908 CG8908 K05643|1|6e-124|446|ecb:100068313|ATP-binding cassette, subfamily A (ABC1), member 3 - - - 36623 1417.00 2.6 3.05 0.230297619421794 Up 0.170618148197068 CG12863 CG12863 - - GO:0046872//metal ion binding - 39473 1049.99 3.83 4.39 0.196876547610401 Up 0.185543521331396 CG14117 CG14117, isoform E - - - - 40134 2056.00 15.33 15.615 0.0265748723617956 Up 0.0846321489895654 Taf6 TBP-associated factor 6, isoform B K03131|1|0.0|1071|dme:Dmel_CG32211|transcription initiation factor TFIID subunit D5 GO:0005667//transcription factor complex GO:0008135//translation factor activity, nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0045449 37539 1762.00 0.39 1.01 1.37280926388955 Up 0.289823008849558 CG3290 CG3290 K01077|1|0.0|1089|dme:Dmel_CG3290|alkaline phosphatase [EC:3.1.3.1] - GO:0016791//phosphatase activity - 31512 957.00 0.42 0.05 -3.0703893278914 Down 0.253203011491216 CG15766 CG15766 K00669|1|3e-09|62.8|dme:Dmel_CG3318|arylalkylamine N-acetyltransferase [EC:2.3.1.87] - - - 42065 3602.00 8.245 8.6 0.0608171661519933 Up 0.10959582617884 cal1 chromosome alignment defect 1 - - - - 19835853 552.00 8.95 7.095 -0.335084998091067 Down 0.367685906749439 19835114 351.00 0.01 0.64 6 Up 0.408268392550522 246577 1154.00 1.495 1.19 -0.329183910890161 Down 0.154008717474574 CG30378 CG30378 K02183|1|6e-32|137|spu:575365|calmodulin GO:0016461//unconventional myosin complex;GO:0015630//microtubule cytoskeleton;GO:0042995//cell projection GO:0032028//myosin head/neck binding;GO:0046872//metal ion binding GO:0000278//mitotic cell cycle;GO:0016059//deactivation of rhodopsin mediated signaling;GO:0007017//microtubule-based process;GO:0032412//regulation of ion transmembrane transporter activity;GO:0051276//chromosome organization;GO:0006464//cellular protein modification process;GO:0009593//detection of chemical stimulus;GO:0042993//positive regulation of transcription factor import into nucleus 32398 3245.00 1.615 1.395 -0.211269042864737 Down 0.115539558842953 NetA Netrin-A, isoform C K06843|1|4e-166|585|spu:576509|netrin 1 GO:0031012//extracellular matrix GO:0005488//binding - 34048 2027.00 27.06 17.2 -0.653753274387077 Down 0.619369964337604 CG13794 CG13794 K03308|1|1e-34|148|isc:IscW_ISCW023444|neurotransmitter:Na+ symporter, NSS family;K05047|2|1e-33|145|ssc:431671|solute carrier family 6 (neurotransmitter transporter) member 14 GO:0016021//integral to membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006810//transport 42686 2919.00 0.755 0.855 0.179447775560819 Up 0.0812640338132347 CG4907 CG4907 K05285|1|2e-124|447|dwi:Dwil_GK21360|phosphatidylinositol glycan, class N [EC:2.7.-.-] GO:0031090//organelle membrane GO:0003824//catalytic activity GO:0006497//protein lipidation 35073 12821.00 0.21 0.2 -0.070389327891398 Down 0.042365605600317 btv beethoven K10414|1|0.0|8185|dme:Dmel_CG15148|dynein heavy chain 2, cytosolic GO:0005875//microtubule associated complex;GO:0031224//intrinsic to membrane GO:0046872//metal ion binding;GO:0003774//motor activity;GO:0032559 GO:0016337//cell-cell adhesion;GO:0007017//microtubule-based process 40826 3713.00 2.325 2.155 -0.109542846906296 Down 0.0901796328094043 pb proboscipedia, isoform D K09302|1|0.0|759|dme:Dmel_CG31481|homeobox protein HoxA/B2 - - GO:0007380//specification of segmental identity, head;GO:0048513//organ development;GO:0007380//specification of segmental identity, head;GO:0048513//organ development;GO:0007380//specification of segmental identity, head;GO:0048513//organ development;GO:0010468//regulation of gene expression;GO:0007380//specification of segmental identity, head;GO:0048513//organ development;GO:0006350 35584 1898.50 91.17 90.22 -0.0151118895240972 Down 0.0878021397437591 Eb1 Eb1, isoform G K10436|1|5e-145|514|dme:Dmel_CG3265|microtubule-associated protein, RP/EB family GO:0005874//microtubule;GO:0005819//spindle;GO:0005874//microtubule;GO:0005819//spindle;GO:0005874//microtubule;GO:0005819//spindle;GO:0005874//microtubule;GO:0005819//spindle;GO:0005874//microtubule;GO:0005819//spindle GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0008344//adult locomotory behavior;GO:0007052//mitotic spindle organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0008344//adult locomotory behavior;GO:0007052//mitotic spindle organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0008344//adult locomotory behavior;GO:0007052//mitotic spindle organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0008344//adult locomotory behavior;GO:0007052//mitotic spindle organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development;GO:0008344//adult locomotory behavior;GO:0007052//mitotic spindle organization;GO:0001700//embryonic development via the syncytial blastoderm;GO:0048513//organ development 35101 771.00 0.105 0.175 0.736965594166206 Up 0.0868115176330736 Ntf-2r nuclear transport factor-2-related - GO:0044464//cell part GO:0008565//protein transporter activity GO:0002777;GO:0006605//protein targeting 40986 910.00 0.135 0.1 -0.432959407276106 Down 0.0678576145819575 CG11698 CG11698 - - - - 35327 4773.14 26.71 20.155 -0.40624219278403 Down 0.530081891427817 CG31678 CG31678, isoform E - - - - 12798148 2004.59 5.6 9.535 0.76780611136779 Up 0.546757363624356 14462384 403.00 0.33 0.12 -1.4594316186373 Down 0.162891295733721 43228 2003.12 2.305 2.145 -0.103789102929792 Down 0.086052040681548 ball ballchen, isoform B K08816|1|0.0|1072|dme:Dmel_CG6386|vaccinia related kinase [EC:2.7.11.1] - GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0051276//chromosome organization;GO:0007126//meiosis;GO:0006468//protein phosphorylation;GO:0051276//chromosome organization;GO:0007126//meiosis;GO:0006468//protein phosphorylation 39338 753.64 933.925 855.96 -0.125763317785419 Down 0.325122176726985 RpL10Ab ribosomal protein L10Ab, isoform F K02865|1|4e-108|390|dsi:Dsim_GD14333|large subunit ribosomal protein L10Ae GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 34129 679.00 213.71 185.145 -0.206998827899999 Down 0.43570862501651 CG14277 CG14277 - - - - 7354406 1691.73 3.895 5.14 0.400145031132209 Up 0.324758948619733 CG42363 CG42363, isoform B - - - - 14462398 448.00 0.385 0.665 0.788495894806288 Up 0.171377625148593 8674120 662.54 2.48 1.31 -0.920773308849425 Down 0.366761326112799 CG42566 CG42566, isoform B - - GO:0046914//transition metal ion binding - 43672 940.00 106.37 142.81 0.425005686329544 Up 0.607053229428081 l(3)03670 lethal (3) 03670 - - - - 12798264 743.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 34225 1537.73 34.78 34.41 -0.0154300405696062 Down 0.0795139347510236 alien alien, isoform E K12176|1|0.0|825|dya:Dyak_GE10643|COP9 signalosome complex subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0060089;GO:0042802//identical protein binding;GO:0051427;GO:0003712//transcription cofactor activity;GO:0060089;GO:0042802//identical protein binding;GO:0051427 GO:0023060;GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0031647//regulation of protein stability;GO:0023060;GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-dependent;GO:0031647//regulation of protein stability 31509 2343.00 224.2 231.67 0.0472849570243383 Up 0.158631620657773 CG12239 CG12239 - - - - 3772115 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 36413 1739.00 0.385 0.27 -0.511899038531433 Down 0.104873860784573 Or49b odorant receptor 49b K08471|1|0.0|751|dme:Dmel_CG17584|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 42684 1305.00 13.985 12.385 -0.175286385229829 Down 0.281270637960639 CG6972 CG6972 - - - - 32485 7385.02 12.565 15.685 0.319974857962947 Up 0.426726984546295 Ac13E adenylyl cyclase 35C, isoform C K08049|1|0.0|2857|dme:Dmel_CG9210|adenylate cyclase 9 [EC:4.6.1.1] - GO:0009975//cyclase activity;GO:0003676//nucleic acid binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0003676//nucleic acid binding;GO:0016829//lyase activity GO:0006259//DNA metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006259//DNA metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process 43487 1761.00 0.11 0.055 -1 Down 0.0796790384361379 CG18110 pickpocket 30, isoform B - GO:0044464//cell part GO:0005261//cation channel activity GO:0030001//metal ion transport 39897 2158.00 16.38 9.745 -0.749201266383118 Down 0.603850217936864 Cpr73D cuticular protein 73D - - GO:0005198//structural molecule activity - 19835782 443.00 0.01 0.32 5 Up 0.281666886804913 2768717 674.00 4.24 2.16 -0.973032952399731 Down 0.465889578655396 CheB42b chemosensory protein B 42b - GO:0044421//extracellular region part - GO:0009593//detection of chemical stimulus 318901 774.00 1.57 1.185 -0.405877499993368 Down 0.180227182670717 CG33159 CG33159 K01312|1|6e-35|147|dpo:Dpse_GA21879|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 12798141 1494.00 7.395 9.905 0.421606827790419 Up 0.428609166556598 34977 1010.00 3.83 1.755 -1.1258733616204 Down 0.477380795139348 jhamt juvenile hormone acid methyltransferase, isoform B K10718|1|3e-173|607|dme:Dmel_CG17330|juvenile hormone acid methyltransferase [EC:2.1.1.-] - - - 34845 545.00 1.055 0.88 -0.261667570069888 Down 0.110190199445252 pburs partner of bursicon - GO:0005615//extracellular space GO:0005179//hormone activity GO:0007166//cell surface receptor signaling pathway 12798266 356.00 0.725 1.5 1.04890960048095 Up 0.31105534275525 33253 2583.00 3.76 4.22 0.166510337029548 Up 0.162296922467309 Pkg21D cGMP-dependent protein kinase 21D K07376|1|0.0|1477|dme:Dmel_CG3324|protein kinase, cGMP-dependent [EC:2.7.11.12] - GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 34182 1212.63 13.98 3.3 -2.08282643112962 Down 0.719455818253863 Bace beta-site APP-cleaving enzyme, isoform B K01379|1|8e-99|360|dme:Dmel_CG6508|cathepsin D [EC:3.4.23.5];K06002|1|8e-99|360|dme:Dmel_CG6508|pepsin A [EC:3.4.23.1] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38294 1344.00 1.425 0.975 -0.547487795302493 Down 0.206544710077929 yellow-g yellow-g - - - - 42935 13267.52 5.365 6.185 0.205195424219848 Up 0.225498613129045 CG5794 puffyeye, isoform I K11853|1|0.0|4890|dme:Dmel_CG5794|ubiquitin carboxyl-terminal hydrolase 34 [EC:3.1.2.15] - GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 34045 4928.00 34.235 19.455 -0.81533103211928 Down 0.665268788799366 Tep3 Thioester-containing protein 3 K06530|1|0.0|880|dpo:Dpse_GA20061|CD109 antigen GO:0044421//extracellular region part GO:0005488//binding;GO:0061135 GO:0042742//defense response to bacterium;GO:0006909//phagocytosis 33866 2650.00 0.145 0.13 -0.15754127698648 Down 0.045238409721305 tectonic tectonic - - - - 31464 2975.00 13.535 11.76 -0.202806827378599 Down 0.30352661471404 CG3239 fra mauro, isoform G K01415|1|1e-19|98.2|cin:100186841|endothelin-converting enzyme [EC:3.4.24.71];K08635|2|1e-18|95.1|dre:560703|membrane metallo-endopeptidase-like 1 - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 50152 359.00 2.03 1.62 -0.325485914300551 Down 0.180755514463083 CG11373 CG11373 - - - - 43777 3006.21 26.695 26.835 0.00754633910855278 Up 0.0576542068418967 CG31999 CG31999, isoform C K06825|1|7e-74|279|gga:373992|fibrillin 1 - - - 19835605 1096.00 0.045 0.085 0.917537839808027 Up 0.0698718795403513 36141 543.00 3.34 3.285 -0.0239547321517225 Down 0.0513472460705323 Lsm10 Lsm10 - GO:0044451//nucleoplasm part - GO:0008334//histone mRNA metabolic process;GO:0006396//RNA processing 42043 1831.01 24.39 13.425 -0.861367669923409 Down 0.652720908730683 Ahcy89E adenosylhomocysteinase 89E, isoform D K01251|1|0.0|944|dme:Dmel_CG8956|adenosylhomocysteinase [EC:3.3.1.1] - - - 34838 659.01 349.81 123.365 -1.50363838792191 Down 0.769746400739664 l(2)34Fc lethal (2) 34Fc, isoform B K07756|1|5e-07|54.3|bfo:BRAFLDRAFT_123507|inositol-hexakisphosphate kinase [EC:2.7.4.21] - - GO:0051707//response to other organism 34858 1318.00 0.725 1.16 0.678071905112637 Up 0.207568352925637 CG4701 CG4701 K13254|1|4e-46|185|isc:IscW_ISCW020482|spastin [EC:3.6.4.3] GO:0031966//mitochondrial membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0007033//vacuole organization;GO:0007281//germ cell development;GO:0006914//autophagy 2768970 1745.00 0.35 0.555 0.66513284940514 Up 0.140668339717342 CG33490 CG33490 - - GO:0046872//metal ion binding - 33132 4071.24 48.5 56.78 0.227398101762539 Up 0.429368643508123 CG14619 CG14619, isoform J K11833|1|0.0|652|dme:Dmel_CG14619|ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15] - GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process 19834739 646.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 31351 2699.00 7.37 8.365 0.182700920943283 Up 0.235735041606129 CG6428 CG6428 K13278|1|0.0|1250|dme:Dmel_CG6428|60kDa lysophospholipase [EC:3.1.1.5 3.1.1.47 3.5.1.1] - GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0006519 318140 3719.00 0.16 0.335 1.06608919045777 Up 0.144102496367719 CG32651 CG32651 - - - - 40923 1432.00 0.215 0.66 1.61812936465636 Up 0.249273543785497 CG18268 CG18268 - - - - 33314 5537.78 14.995 19.19 0.35587318932664 Up 0.472526746796989 robo3 robo3, isoform B K06754|1|1e-148|528|gga:395291|roundabout, axon guidance receptor 2;K06753|5|5e-147|522|dre:30769|roundabout, axon guidance receptor 1 GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0006935//chemotaxis;GO:0008037//cell recognition;GO:0007420//brain development 43267 1556.00 2.745 2.925 0.091630475465568 Up 0.088033284902919 CG6066 CG6066 - - - GO:0000377 19835695 529.00 0.24 0.11 -1.12553088208386 Down 0.122407872143706 31110 2896.66 26.95 27.31 0.0191440411254186 Up 0.0791507066437723 inc insomniac, isoform D K04892|1|5e-06|53.9|dre:570188|potassium voltage-gated channel Shal-related subfamily D member 2;K05321|2|9e-06|53.1|nve:NEMVE_v1g135889|potassium voltage-gated channel Shal-related subfamily D, invertebrate - - - 47852 243.00 125.13 112.83 -0.149277005848919 Down 0.344868577466649 Acp95EF accessory gland protein 95EF - - - - 34318 1763.00 0.305 0.275 -0.149377624038226 Down 0.0552767137762515 TbCMF46 TbCMF46 K01768|1|5e-10|66.2|mcc:700574|adenylate cyclase [EC:4.6.1.1];K11293|3|2e-09|64.3|cel:K10D2.1|protein HIRA/HIR1;K03994|5|6e-09|62.8|dre:565774|complement component 5 GO:0044464//cell part GO:0005488//binding GO:0023060 35364 963.00 3.405 4.83 0.504368390823702 Up 0.357746664905561 RPA2 replication protein A2, isoform B K10739|1|2e-126|451|dme:Dmel_CG9273|replication factor A2 GO:0043234//protein complex GO:0005488//binding GO:0006260//DNA replication 19835897 568.00 0.235 0.175 -0.425305834732671 Down 0.0781931052701096 36543 735.00 1.735 4.09 1.23716518036349 Up 0.504721965394268 DJ-1alpha DJ-1alpha K05687|1|3e-106|384|dme:Dmel_CG6646|protein DJ-1;K03152|3|4e-41|167|aag:AaeL_AAEL004081|4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis - - GO:0006950//response to stress;GO:0007626//locomotory behavior 36158 2481.00 3.06 2.17 -0.495836610248172 Down 0.287478536520935 CG12942 CG12942 K10513|1|7e-32|139|tgu:100229532|zinc finger and BTB domain-containing protein 41 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 32598 1646.74 44.34 52.845 0.253158205348813 Up 0.447893276977942 CG9919 CG9919, isoform B - - - - 40728 1797.24 266.745 147.95 -0.850351532183056 Down 0.716483951921807 CG1213 CG1213, isoform D K08145|1|6e-63|242|gga:378802|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0022857//transmembrane transporter activity;GO:0022857//transmembrane transporter activity GO:0006810//transport;GO:0006810//transport 34922 1483.00 1.085 0.475 -1.19169562411353 Down 0.280213974375908 CG18477 CG18477 K01312|1|1e-29|131|dpo:Dpse_GA18102|trypsin [EC:3.4.21.4];K01324|2|7e-26|118|cfa:475624|plasma kallikrein [EC:3.4.21.34];K01316|3|3e-25|116|mmu:19146|protease, serine, 7 (enterokinase) [EC:3.4.21.9];K09628|4|5e-25|115|xla:397795|protease, serine 27 [EC:3.4.21.-];K09614|5|8e-25|115|dpo:Dpse_GA15245|corin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31457 2485.00 16.385 11.625 -0.495144956660004 Down 0.526449610355303 NAAT1 nutrient amino acid transporter 1 K05336|1|0.0|1182|dme:Dmel_CG3252|solute carrier family 6 (neurotransmitter transporter), invertebrate GO:0016021//integral to membrane GO:0015171//amino acid transmembrane transporter activity;GO:0005343//organic acid:sodium symporter activity;GO:0005326//neurotransmitter transporter activity GO:0006865//amino acid transport;GO:0030001//metal ion transport 39074 864.00 80.035 62.715 -0.351820496947016 Down 0.551050059437327 CG4461 CG4461 K09542|1|5e-13|74.7|dre:30393|crystallin, alpha B;K09541|4|8e-09|60.8|xla:378668|crystallin, alpha A;K04455|5|7e-08|57.8|cin:100177240|heat shock 27kDa protein 1 GO:0015630//microtubule cytoskeleton - GO:0010259//multicellular organismal aging 5740523 1012.00 44.415 63.615 0.518319992418881 Up 0.623134328358209 34651 3271.00 0.105 0.255 1.28010791919274 Up 0.13333773609827 Pkd2 polycystic kidney disease 2 ortholog K04986|1|0.0|1535|dme:Dmel_CG6504|polycystin 2;K04990|3|7e-83|309|ssc:100154788|polycystin 2L1 GO:0044464//cell part GO:0046872//metal ion binding;GO:0005216//ion channel activity GO:0048870//cell motility;GO:0006936//muscle contraction;GO:0030537//larval behavior 40529 1564.00 23.395 22.245 -0.0727191301845242 Down 0.165235768062343 CG14641 CG14641 K12872|1|0.0|838|dme:Dmel_CG14641|pre-mRNA-splicing factor RBM22/SLT11 GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0000380//alternative mRNA splicing, via spliceosome 5740565 4319.72 38.415 41.87 0.124247164421678 Up 0.271397437590807 CG34370 CG34370, isoform H K09608|1|2e-11|72.4|mdo:100015628|tolloid-like protein 1 [EC:3.4.24.-];K13045|2|1e-10|69.7|dgr:Dgri_GH18446|tolloid [EC:3.4.24.-];K13046|3|5e-10|67.8|ame:410386|tolkin [EC:3.4.24.-] - - - 39667 1414.00 0.54 1.3 1.26748031086499 Up 0.316140536256769 CG13455 CG13455 - - - - 43274 1455.00 23.78 12.98 -0.873458331746517 Down 0.653414344208163 CG5909 CG5909 K01312|1|2e-42|173|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01362|2|2e-39|163|dme:Dmel_CG4920| [EC:3.4.21.-];K01323|5|2e-29|130|ecb:100056603|coagulation factor XI [EC:3.4.21.27] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 33545 1837.14 9.58 15.165 0.662647936887991 Up 0.572315414080042 CG8837 CG8837, isoform B K08145|1|1e-15|85.1|spu:582285|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8;K08144|4|4e-12|73.2|ptr:473154|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6 GO:0031224//intrinsic to membrane - GO:0006810//transport 40278 1699.16 116.83 83.955 -0.476722628303394 Down 0.625016510368511 CG5059 CG5059, isoform E - GO:0031224//intrinsic to membrane;GO:0031967;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0006915//apoptotic process;GO:0006915//apoptotic process;GO:0006915//apoptotic process;GO:0006915//apoptotic process 37934 1099.00 5.55 5.57 0.00518955610256339 Up 0.0432901862369568 CG3570 CG3570 - - GO:0016741 - 40530 1995.00 8.555 9.195 0.104081719922525 Up 0.160777968564258 abs abstrakt K13116|1|0.0|1184|dme:Dmel_CG14637|ATP-dependent RNA helicase DDX41 [EC:3.6.4.13] GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032559 GO:0012501//programmed cell death;GO:0048731;GO:0007163//establishment or maintenance of cell polarity;GO:0000377;GO:0009207 3346223 1170.00 0.17 0.365 1.10236171762968 Up 0.148857482499009 CG33511 CG33511 - - - - 39475 3357.00 11.44 12.395 0.115671219308333 Up 0.199940562673359 MICAL-like MICAL-like K05699|1|2e-21|105|nve:NEMVE_v1g206855|actinin alpha - GO:0046914//transition metal ion binding - 43561 1992.00 0.405 0.405 0 - 0.0382380134724607 CG7912 CG7912 K03321|1|8e-39|162|rno:64076|sulfate permease, SulP family;K04602|2|1e-33|145|gga:416011|cadherin EGF LAG seven-pass G-type receptor 3 (flamingo);K13962|3|3e-26|120|gga:428369|solute carrier family 26 (sulfate anion transporter), member 7 GO:0031224//intrinsic to membrane - GO:0006810//transport 50397 361.00 401.8 331.92 -0.275642001749004 Down 0.515321621978603 CG11368 CG11368 - - - - 42424 320.00 2.215 2.03 -0.125826971369842 Down 0.0967507594769515 MtnB metallothionein B, isoform C - - GO:0046914//transition metal ion binding GO:0030003//cellular cation homeostasis 42860 6762.92 1.325 1.915 0.531352032474395 Up 0.236626601505746 Rootletin rootletin, isoform F K11498|1|3e-35|152|aga:AgaP_AGAP006472|centromeric protein E;K10352|2|4e-35|151|dre:555454|myosin heavy chain - - - 32773 1150.00 3.355 2.83 -0.245510713368301 Down 0.187458724078721 CG6788 CG6788 K10104|1|6e-38|158|cqu:CpipJ_CPIJ000937|ficolin;K06252|4|2e-35|149|dre:369191|tenascin GO:0044421//extracellular region part GO:0005515//protein binding GO:0023060 35661 753.39 1.565 0.705 -1.15046749453383 Down 0.328919561484612 CG1701 CG1701, isoform C - - - - 41109 2325.95 63.46 74.56 0.232554338736643 Up 0.439307885352001 CG8861 CG8861, isoform C K04008|1|2e-93|343|dme:Dmel_CG8861|CD59 antigen - - - 40578 1139.00 1.32 1.015 -0.379058202173277 Down 0.157839122969225 slx1 nuclease slx1 K13882|1|7e-31|134|mdo:100014449|coronin-1A GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004518//nuclease activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress 33319 628.92 3 3.055 0.0262098793228486 Up 0.0530643243957205 Cdlc2 cytoplasmic dynein light chain 2, isoform C K10418|1|7e-47|186|ame:725312|dynein light chain LC8-type GO:0030286//dynein complex;GO:0030286//dynein complex GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0016887//ATPase activity;GO:0042802//identical protein binding;GO:0003774//motor activity;GO:0045502//dynein binding;GO:0016887//ATPase activity GO:0044248//cellular catabolic process;GO:0007472//wing disc morphogenesis;GO:0007015//actin filament organization;GO:0048232//male gamete generation;GO:0007017//microtubule-based process;GO:0006997//nucleus organization;GO:0048102//autophagic cell death;GO:0003006//developmental process involved in reproduction;GO:0044248//cellular catabolic process;GO:0007472//wing disc morphogenesis;GO:0007015//actin filament organization;GO:0048232//male gamete generation;GO:0007017//microtubule-based process;GO:0006997//nucleus organization;GO:0048102//autophagic cell death;GO:0003006//developmental process involved in reproduction 39035 3944.82 11.54 11.575 0.00436896950211638 Up 0.0434552899220711 CG5087 CG5087, isoform B K10588|1|0.0|2071|dme:Dmel_CG5087|ubiquitin-protein ligase E3 B [EC:6.3.2.19] GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification 43126 3964.06 20.66 21.3 0.044013176248141 Up 0.114020604939902 CG5890 CG5890, isoform D K13764|1|1e-25|117|mdo:100027210|recoverin - GO:0046872//metal ion binding;GO:0005216//ion channel activity;GO:0046872//metal ion binding;GO:0005216//ion channel activity GO:0007267//cell-cell signaling;GO:0023060;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009593//detection of chemical stimulus;GO:0007267//cell-cell signaling;GO:0023060;GO:0007450//dorsal/ventral pattern formation, imaginal disc;GO:0009593//detection of chemical stimulus 36265 716.00 0.76 0.88 0.211504105193712 Up 0.0889578655395588 TwdlBeta TwdlBeta - - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 38409 364.00 93.155 27 -1.78667379915987 Down 0.771496499801876 Drsl5 Drosomycin-like 5 - - - GO:0050832//defense response to fungus;GO:0042742//defense response to bacterium 33622 1925.00 1.995 3.155 0.661251258760203 Up 0.342028794082684 CG2955 CG2955 K10436|1|1e-19|98.2|xla:398932|microtubule-associated protein, RP/EB family - - - 40865 897.85 4.21 10.45 1.31161080390185 Up 0.642682604675736 CG1288 CG1288, isoform B - - - - 42003 638.02 14.365 10.275 -0.483419598963479 Down 0.505184255712588 Dhfr dihydrofolate reductase, isoform B K00287|1|5e-103|372|dme:Dmel_CG14887|dihydrofolate reductase [EC:1.5.1.3] - - - 10178958 796.00 0.25 0.28 0.16349873228288 Up 0.0554418174613657 CG42814 CG42814 K08077|1|1e-31|135|gga:423501|UDP-sugar diphosphatase [EC:3.6.1.45] - GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0043169//cation binding - 42730 1313.00 0.35 0.505 0.528928465806829 Up 0.120261524237221 CG17109 CG17109, isoform B K01436|1|0.0|812|dme:Dmel_CG17109|aminoacylase [EC:3.5.1.14] GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding GO:0006519 42505 792.98 142.73 107.77 -0.405332972437358 Down 0.597411174217409 CG5793 CG5793, isoform E - - - - 42652 4483.63 17.945 21.345 0.250316239431561 Up 0.392220314357416 oa2 octopamine beta1 receptor, isoform E K04141|1|1e-57|224|gga:430991|adrenergic receptor beta-1;K04160|2|5e-57|222|ecb:100034053|5-hydroxytryptamine (serotonin) receptor 4;K04142|4|1e-56|221|cfa:403910|adrenergic receptor beta-2 GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0008227//G-protein coupled amine receptor activity;GO:0008227//G-protein coupled amine receptor activity;GO:0008227//G-protein coupled amine receptor activity GO:0007204//elevation of cytosolic calcium ion concentration;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 39741 893.00 1.965 1.615 -0.282995147564681 Down 0.158763703605864 CG17028 CG17028, isoform B K01092|1|5e-164|576|dme:Dmel_CG17028|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] - GO:0004437//inositol or phosphatidylinositol phosphatase activity;GO:0004437//inositol or phosphatidylinositol phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process 3355165 1439.75 146.6 189.01 0.366577462026247 Up 0.580471536124686 CG40485 CG40485, isoform B K11166|1|4e-18|92.4|cqu:CpipJ_CPIJ009166|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-];K11165|3|9e-18|91.3|mdo:100026820|dehydrogenase/reductase SDR family member 7 [EC:1.1.-.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process 4379890 2551.00 0.13 0.18 0.46948528330122 Up 0.0740655131422533 CG34109 CG34109 - - - - 5740695 200.00 0.135 0.01 -3.75488750216347 Down 0.155263505481442 43090 2250.65 6.525 7.825 0.262112850362734 Up 0.29401664245146 CG5071 CG5071, isoform C K01802|1|0.0|922|dme:Dmel_CG5071|peptidylprolyl isomerase [EC:5.2.1.8] GO:0044464//cell part;GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016859//cis-trans isomerase activity;GO:0046914//transition metal ion binding;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process 19835240 687.00 0.01 0.07 2.8073549220576 Up 0.100680227182671 41487 1577.00 0.05 0.11 1.13750352374993 Up 0.0858869369964338 Cyp313a2 Cyp313a2 K00517|1|0.0|980|dme:Dmel_CG10094| [EC:1.14.-.-] - - - 50110 537.00 650.475 375.005 -0.794583778843116 Down 0.713446044115705 CG11458 CG11458 - - - - 37573 6512.34 18.08 21.18 0.228307911577149 Up 0.372341830669661 px plexus, isoform E - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0032559;GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0032559 GO:0002118//aggressive behavior;GO:0009206;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0006811//ion transport;GO:0002118//aggressive behavior;GO:0009206;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0006811//ion transport 41320 3180.00 7.875 7.37 -0.0956153041795715 Down 0.145324263637564 CG4674 leash - - - - 37781 2199.74 45.275 51.74 0.192565412847211 Up 0.380597014925373 TBPH TAR DNA-binding protein-43 homolog, isoform F K12741|1|8e-20|99.0|api:100168877|heterogeneous nuclear ribonucleoprotein A1/A3;K13044|2|7e-19|95.9|api:100165781|heterogeneous nuclear ribonucleoprotein A/B/D;K13158|4|2e-18|94.4|xla:380082|heterogeneous nuclear ribonucleoprotein A2/B1 - GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior;GO:0048741//skeletal muscle fiber development;GO:0007626//locomotory behavior 34536 506.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 CG14915 CG14915 - - - - 33509 3261.00 3.38 2.295 -0.558529092868376 Down 0.322447497028134 CG17265 CG17265 - - - - 38332 2290.67 5.07 6.13 0.273901326687441 Up 0.271595562012944 CG42304 CG42304, isoform B K13151|1|0.0|872|dsi:Dsim_GD13702|snurportin-1 - - - 49779 2378.78 17.995 15.815 -0.186302546407334 Down 0.315942411834632 PpD3 protein phosphatase D3, isoform C K04460|1|0.0|1073|dme:Dmel_CG8402|protein phosphatase 5 [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process;GO:0007049//cell cycle;GO:0006464//cellular protein modification process;GO:0007049//cell cycle 5740592 2269.00 2.625 3.805 0.53557903095006 Up 0.33456610751552 ATbp (A+T)-stretch binding protein K09228|1|7e-07|56.2|api:100159445|KRAB domain-containing zinc finger protein;K09223|5|2e-06|54.7|dre:798697|growth factor independent 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0006355//regulation of transcription, DNA-dependent 40439 5378.00 11.925 14.15 0.246812786826371 Up 0.351274600449082 CG14562 CG14562, isoform B - - - - 37651 920.00 0.095 0.1 0.0740005814437768 Up 0.042365605600317 CG9897 CG9897, isoform B K01312|1|4e-25|115|dme:Dmel_CG30031|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31676 769.00 1.485 2.055 0.468675462880917 Up 0.228371417250033 CG12689 CG12689 - - - - 36644 1243.16 7.12 6.87 -0.0515671421482975 Down 0.0905758816536785 CG42254 CG42254, isoform D - GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0031490//chromatin DNA binding GO:0051276//chromosome organization;GO:0007292//female gamete generation 41854 1687.00 0.03 0.135 2.16992500144231 Up 0.120954959714701 CG14866 CG14866, isoform B - - - - 36853 1052.65 112.685 73.15 -0.62336571528062 Down 0.665995245013869 CG8317 CG8317, isoform C - - - - 19836030 609.00 0.01 0.27 4.75488750216347 Up 0.252509576013737 - CG45489 - - - - 10178907 482.00 0.36 0.42 0.222392421336448 Up 0.069937921014397 19834972 443.00 0.375 0.01 -5.22881869049588 Down 0.306333377360983 45785 3862.05 15.19 15.545 0.0333287468389805 Up 0.0899154669132215 Aats-ile Isoleucyl-tRNA synthetase, isoform D K01870|1|0.0|2486|dme:Dmel_CG11471|isoleucyl-tRNA synthetase [EC:6.1.1.5] GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0046914//transition metal ion binding;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0046914//transition metal ion binding;GO:0032559;GO:0004812//aminoacyl-tRNA ligase activity;GO:0046914//transition metal ion binding;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation 33349 3600.36 7.25 5.775 -0.328160048598877 Down 0.333476423193766 frtz fritz, isoform D K03626|1|8e-06|53.5|mmu:17938|nascent polypeptide-associated complex subunit alpha - - GO:0001737//establishment of imaginal disc-derived wing hair orientation 42075 1126.00 0.39 0.785 1.00921853002938 Up 0.218267071721041 TwdlW TweedleW - - - - 19835280 551.00 0.78 0.875 0.16580889297008 Up 0.0781600845330868 31715 639.00 0.385 0.355 -0.117039421190219 Down 0.0528661999735834 CG15330 CG15330 - - - - 33048 8977.22 12.095 12.725 0.0732548869831327 Up 0.140073966450931 RhoGAP19D Rho GTPase activating protein at 19D, isoform E K02649|1|7e-20|101|bfo:BRAFLDRAFT_91712|phosphoinositide-3-kinase, regulatory subunit;K05732|2|9e-20|100|ecb:100065944|glucocorticoid receptor DNA-binding factor 1 - - - 41102 708.00 8.455 9.765 0.207815289476808 Up 0.276779817725532 CG9740 insulator binding factor 2 - - - - 12798278 224.00 8.91 7.765 -0.198439507134621 Down 0.258321225729758 CG43319 CG43319 - - - - 37188 4042.00 7.17 7.57 0.0783201812838271 Up 0.123464535728437 Topors topoisomerase I-interacting protein, isoform B K10631|1|0.0|1503|dme:Dmel_CG15104|E3 ubiquitin-protein ligase Topors [EC:6.3.2.19] - - - 32006 1257.39 34.48 25.265 -0.448619594471145 Down 0.569178444062871 CG15211 CG15211, isoform E - GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 42518 3409.00 7.28 7.24 -0.00794875311549072 Down 0.0472856954167217 Oga O-GlcNAcase K01197|1|0.0|1929|dme:Dmel_CG5871|hyaluronoglucosaminidase [EC:3.2.1.35];K11449|2|2e-54|214|spu:589728|jumonji domain-containing protein 1 [EC:1.14.11.-] - GO:0016407//acetyltransferase activity - 5740752 533.00 10.32 6.795 -0.602897514655863 Down 0.509576013736627 CG34183 CG34183 - - - - 42582 1776.00 1 1.2 0.263034405833794 Up 0.115638621054022 CG6690 CG6690 K10758|1|1e-84|313|dme:Dmel_CG31413|thiol oxidase [EC:1.8.3.2] - GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor GO:0008152//metabolic process;GO:0019725//cellular homeostasis 33408 686.00 1.26 1.9 0.592575684831031 Up 0.250990622110686 CG4270 CG4270, isoform B - - - - 33338 3058.00 11.775 10.705 -0.137442264114636 Down 0.222625809008057 CG31935 CG31935 - - - - 14462587 586.00 0.075 0.08 0.0931094043914812 Up 0.0382380134724607 318244 1362.22 1.67 2.065 0.306293678945393 Up 0.175670320961564 CG32846 CG32846, isoform B - - - - 38611 2529.00 31.845 35.96 0.175326148887913 Up 0.349920750231145 Klp64D Kinesin-like protein at 64D K10394|1|0.0|1217|dme:Dmel_CG10642|kinesin family member 3/17 GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032559 GO:0006935//chemotaxis;GO:0008088//axon cargo transport;GO:0042384//cilium assembly;GO:0003006//developmental process involved in reproduction 41410 1344.00 78.27 79.98 0.0311798362715207 Up 0.110652489763572 CG6908 CG6908, isoform B - - - - 19835880 735.00 0.01 0.08 3 Up 0.110718531237617 36571 4260.72 41.905 45.91 0.131686039084115 Up 0.29078061022322 cg combgap, isoform M K09228|1|4e-70|266|ecb:100061107|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis;GO:0007472//wing disc morphogenesis 246415 4128.00 0.075 0.125 0.736965594166206 Up 0.0760797781006472 CG30048 CG30048, isoform D K04988|1|6e-09|63.9|bfo:BRAFLDRAFT_92411|polycystin 1L2;K04985|2|2e-08|62.0|mdo:100012596|polycystin 1 - - - 38340 479.00 39.63 28.705 -0.465290911696714 Down 0.584434024567428 Acp62F accessory gland protein 62F - - GO:0004866//endopeptidase inhibitor activity GO:0010259//multicellular organismal aging;GO:0030162//regulation of proteolysis 36877 2126.00 0.3 0.38 0.341036917835067 Up 0.0855567296262053 CG5348 CG5348, isoform C K13754|1|4e-161|568|dwi:Dwil_GK21735|solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 - - - 37058 1221.00 11.415 4.84 -1.23785190695011 Down 0.642220314357416 CG10911 CG10911 - - - - 36919 2475.00 54.825 37.72 -0.539504230885859 Down 0.625478800686831 fat-spondin fat-spondin K04659|1|3e-11|70.9|oaa:100082089|thrombospondin;K09609|3|3e-11|70.9|oaa:100073819|a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-];K04596|5|1e-10|68.9|ptr:472871|brain-specific angiogenesis inhibitor 1 - - - 32201 2304.00 2.475 2.145 -0.206450877467426 Down 0.143144894994056 CG2556 CG2556 - - GO:0022892 GO:0051234//establishment of localization 41417 1154.64 18.495 22.18 0.262124065037715 Up 0.406254127592128 CG14721 CG14721, isoform B K00949|1|0.0|678|dme:Dmel_CG14721|thiamine pyrophosphokinase [EC:2.7.6.2] - GO:0016778;GO:0032559 GO:0042723//thiamine-containing compound metabolic process;GO:0009108//coenzyme biosynthetic process 42905 1814.00 12.04 12.065 0.00299252345604958 Up 0.0427618544445912 Golgin84 Golgin-84 ortholog K10352|1|2e-10|67.8|bta:404108|myosin heavy chain;K10388|5|1e-09|65.1|mcc:699517|plectin - - - 34469 607.74 125.64 96.795 -0.376291416786591 Down 0.579976225069344 CG7296 CG7296, isoform B - - - - 34954 1947.83 0.875 1.315 0.587707877459974 Up 0.206148461233655 twe twine, isoform D K01104|1|0.0|765|dme:Dmel_CG4965|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0004721//phosphoprotein phosphatase activity GO:0048731;GO:0006996//organelle organization;GO:0048598//embryonic morphogenesis;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0007143//female meiosis;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0007017//microtubule-based process;GO:0003006//developmental process involved in reproduction;GO:0007140//male meiosis;GO:0006464//cellular protein modification process 37903 908.32 1.285 2.72 1.08183829205646 Up 0.410249636771893 CG3494 CG3494, isoform B K10641|1|7e-15|80.9|ptr:464747|E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19] - GO:0005488//binding;GO:0005488//binding GO:0006909//phagocytosis;GO:0006909//phagocytosis 38850 4496.00 0.36 0.145 -1.31194400631474 Down 0.164377228899749 frac faulty attraction, isoform G K06825|1|8e-100|366|ecb:100055741|fibrillin 1 - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - 40173 1253.00 5.43 6.85 0.335151790043528 Up 0.331462158235372 Mtr3 Mtr3 K12587|1|3e-31|135|aag:AaeL_AAEL006697|exosome complex component MTR3, animal type GO:0000178//exosome (RNase complex) GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0010467//gene expression 117461 506.00 0.01 0.115 3.52356195605701 Up 0.136970017170783 TotF turandot F - GO:0044421//extracellular region part - GO:0051707//response to other organism;GO:0009416//response to light stimulus;GO:0006952//defense response 2768998 1754.00 10.5 8.15 -0.365517363435045 Down 0.408334434024567 CG33230 CG33230 - GO:0031224//intrinsic to membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 31063 1430.00 0.19 0.125 -0.604071323668861 Down 0.0797781006472064 CG14627 CG14627, isoform B - - - - 43044 493.00 24.45 24.455 0.000294999498193366 Up 0.0382380134724607 CG11858 CG11858 K09579|1|5e-56|216|dya:Dyak_GE23581|peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8] GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton GO:0016859//cis-trans isomerase activity;GO:0003676//nucleic acid binding GO:0044267//cellular protein metabolic process 33397 1044.00 59.39 42.825 -0.471766786317188 Down 0.602859595826179 Uch ubiquitin carboxy-terminal hydrolase, isoform C K05609|1|3e-130|464|dme:Dmel_CG4265|ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process 37198 3608.00 8.205 7.68 -0.0953970227925566 Down 0.148692378813895 botv brother of tout-velu K02370|1|0.0|1791|dme:Dmel_CG15110|alpha-1,4-N-acetylglucosaminyltransferase EXTL3 [EC:2.4.1.223 2.4.1.224] - - - 19834866 802.00 2 1.62 -0.3040061868901 Down 0.169792629771497 42602 4788.29 0.52 0.765 0.55694812455156 Up 0.14700832122573 Gld2 Gld2, isoform C K00970|1|0.0|2289|dme:Dmel_CG5732|poly(A) polymerase [EC:2.7.7.19];K13291|3|7e-24|114|gga:427463|terminal uridylyltransferase [EC:2.7.7.52] - GO:0070566//adenylyltransferase activity GO:0000278//mitotic cell cycle;GO:0007097//nuclear migration;GO:0001775//cell activation;GO:0000741//karyogamy;GO:0031124//mRNA 3'-end processing;GO:0000226//microtubule cytoskeleton organization;GO:0007143//female meiosis;GO:0003006//developmental process involved in reproduction;GO:0006403//RNA localization 37788 942.00 1.365 1.725 0.337695410745679 Up 0.170320961563862 PHDP putative homeodomain protein K09330|1|2e-27|122|dre:404602|paired mesoderm homeobox protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0034061 GO:0006260//DNA replication;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 43006 836.00 5.595 5.89 0.0741295028540666 Up 0.103189803196407 CG11839 CG11839 K13104|1|1e-145|515|dme:Dmel_CG11839|zinc finger protein 830 - - - 43260 901.00 12.33 4.435 -1.47516679010178 Down 0.672533350944393 CG14258 CG14258 - - - - 40116 2673.00 0.045 0.05 0.15200309344505 Up 0.0382380134724607 brv1 brivido-1 K04986|1|4e-15|84.0|rno:498328|polycystin 2 GO:0044464//cell part GO:0046872//metal ion binding GO:0070838//divalent metal ion transport 43384 1138.00 21.3 20.77 -0.0363522142685528 Down 0.109463743230749 Noa36 Noa36 - GO:0044427//chromosomal part;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding - 19835204 516.00 0.01 0.095 3.24792751344359 Up 0.120756835292564 43414 3240.53 34.5 42.38 0.296787225819276 Up 0.487419099194294 CG33203 CG33203, isoform F K07297|1|9e-17|89.7|oaa:100093572|adiponectin receptor GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - - 42456 1013.00 176.59 107.995 -0.709439128456916 Down 0.691289129573372 CG31199 CG31199 K01344|1|6e-07|55.1|xla:380116|protein C (activated) [EC:3.4.21.69];K09630|2|1e-06|54.3|mmu:77613|protease, serine, 36 [EC:3.4.21.-];K09614|3|2e-06|53.5|dpo:Dpse_GA15245|corin [EC:3.4.21.-];K01314|4|2e-06|53.1|gga:395876|coagulation factor X [EC:3.4.21.6] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 50228 1086.00 0.075 0.085 0.180572245641821 Up 0.045667679302602 CG17580 CG17580 - - - - 14462592 1275.00 0.185 0.185 0 - 0.0382380134724607 14462443 1853.00 6.605 9.38 0.506029361268549 Up 0.461431779157311 39254 1194.00 53.82 37.895 -0.506134884298829 Down 0.614218729362039 Ufd1-like ubiquitin fusion-degradation 1-like K14016|1|2e-168|591|dme:Dmel_CG6233|ubiquitin fusion degradation protein 1 GO:0043234//protein complex - GO:0019941//modification-dependent protein catabolic process 33442 1493.00 0.92 0.86 -0.0972972013549149 Down 0.061352529388456 CG9883 early boundary activity 2 - - - - 32690 4628.60 16.37 17.305 0.0801346196912943 Up 0.166919825650509 CG8949 CG8949, isoform G - - - - 42050 2368.00 0.875 0.755 -0.21280637250725 Down 0.0889578655395588 CG8907 CG8907, isoform B K07365|1|4e-07|57.0|smm:Smp_014850|NCK adaptor protein - - - 3771729 529.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 His3:CG33842 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 50102 1060.00 0.185 0.165 -0.165059246270496 Down 0.0510500594373266 CG18673 CG18673 K01672|1|1e-170|598|dme:Dmel_CG18673|carbonic anhydrase [EC:4.2.1.1];K01743|1|1e-170|598|dme:Dmel_CG18673| [EC:4.2.-.-] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 19835103 2794.72 11.04 12.065 0.128087743437582 Up 0.212983753797385 318014 642.00 0.125 0.075 -0.736965594166206 Down 0.0760797781006472 Cpr65Av cuticular protein 65Av - - GO:0005198//structural molecule activity - 39364 1158.00 19.615 26.26 0.420909580815791 Up 0.535134064192313 viaf viral IAP-associated factor K08327|1|7e-07|55.1|bta:287007|phosducin - GO:0005488//binding GO:0042981//regulation of apoptotic process 40521 5491.73 31.86 34.315 0.107093087818274 Up 0.245575221238938 nAcRalpha-80B nicotinic acetylcholine receptor alpha4, isoform G K05312|1|0.0|943|cqu:CpipJ_CPIJ011539|nicotinic acetylcholine receptor, invertebrate GO:0044459//plasma membrane part;GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport 34373 1746.00 13.66 12.945 -0.0775625183899793 Down 0.154041738211597 CG4953 CG4953 - - - - 14462747 677.00 0.12 0.265 1.14295795384204 Up 0.131554616299036 39842 1428.01 65.5 62.79 -0.0609600943353095 Down 0.171542728833708 mbf1 multiprotein bridging factor 1, isoform E K03627|1|2e-79|295|dan:Dana_GF23918|putative transcription factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0000166//nucleotide binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0000166//nucleotide binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060541//respiratory system development;GO:0048812//neuron projection morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060541//respiratory system development;GO:0048812//neuron projection morphogenesis 39931 909.00 0.845 0.47 -0.846290584604547 Down 0.20215295205389 CG13727 CG13727 - - - - 35431 1624.00 0.235 0.235 0 - 0.0382380134724607 CG11629 CG11629 - - - - 5740848 474.00 20.2 19.425 -0.0564406943440849 Down 0.141328754457799 CG34229 CG34229 - - - - 34004 2503.00 15.425 16.25 0.0751692287663989 Up 0.160612864879144 ico iconoclast K02355|1|0.0|1389|dme:Dmel_CG4567|elongation factor EF-G [EC:3.6.5.3] GO:0043231//intracellular membrane-bounded organelle GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0006414//translational elongation 38761 2379.00 0.61 1.295 1.08607095012367 Up 0.29193633601902 CG10064 CG10064 K11856|1|2e-108|393|mcc:722040|ubiquitin carboxyl-terminal hydrolase 43 [EC:3.1.2.15];K12857|3|1e-14|82.4|spu:578850|Prp8 binding protein;K03130|5|1e-14|82.4|bfo:BRAFLDRAFT_274913|transcription initiation factor TFIID subunit D4 - - - 246446 834.00 0.105 0.055 -0.932885804141463 Down 0.0768722757891956 CG30087 CG30087 K08667|1|1e-32|139|cfa:476402|kallikrein 6 (neurosin, zyme) [EC:3.4.21.-];K09632|2|7e-32|137|dre:447843|chymotrypsin-like protease [EC:3.4.21.-];K01312|4|9e-31|133|ssc:100302368|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 319064 672.78 270.51 180.045 -0.587324392210089 Down 0.670387003037908 CG31997 CG31997, isoform B - - - - 32342 923.00 13.96 16.945 0.279560695274342 Up 0.40037643640206 CG11103 CG11103 - - - - 43640 1949.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 PH4alphaPV prolyl-4-hydroxylase-alpha PV K00472|1|0.0|1016|dme:Dmel_CG31015|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0019471 53540 1545.00 0.585 0.675 0.206450877467427 Up 0.0795799762250693 CG3706 CG3706 K01007|1|2e-08|61.2|bfo:BRAFLDRAFT_121021|pyruvate, water dikinase [EC:2.7.9.2] - - - 43650 6522.00 3.565 4.085 0.196434001701795 Up 0.178675208030643 zfh1 Zn finger homeodomain 1, isoform E K09299|1|0.0|1182|dme:Dmel_CG1322|zinc finger homeobox protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007411//axon guidance;GO:0009888//tissue development;GO:0008354//germ cell migration;GO:0010468//regulation of gene expression;GO:0006959//humoral immune response;GO:0048534;GO:0001700//embryonic development via the syncytial blastoderm;GO:0045137//development of primary sexual characteristics;GO:0042386//hemocyte differentiation;GO:0006350;GO:0007411//axon guidance;GO:0009888//tissue development;GO:0008354//germ cell migration;GO:0010468//regulation of gene expression;GO:0006959//humoral immune response;GO:0048534;GO:0001700//embryonic development via the syncytial blastoderm;GO:0045137//development of primary sexual characteristics;GO:0006351//transcription, DNA-dependent;GO:0042386//hemocyte differentiation 32249 717.00 0.335 0.68 1.02137365079257 Up 0.202582221635187 CG15719 CG15719, isoform D K02151|1|5e-07|54.3|dre:436799|V-type H+-transporting ATPase subunit F [EC:3.6.3.14] GO:0033176 GO:0015078//hydrogen ion transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity GO:0006754//ATP biosynthetic process 41097 1938.96 1.37 1.8 0.393821013369148 Up 0.190628714832915 CG8420 CG8420, isoform B - - - - 43293 954.00 26.135 21.29 -0.295807209507599 Down 0.455851274600449 bigmax bigmax K09113|1|2e-114|411|dme:Dmel_CG3350|MAX-like protein X GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0048102//autophagic cell death 40546 3447.83 23.735 26.165 0.140622209185283 Up 0.281666886804913 CG9776 CG9776, isoform B - - - - 35600 1598.85 1.475 2.1 0.509674373416919 Up 0.24154669132215 Spn42Dc serpin 42Dc, isoform B K13963|1|3e-145|515|dpe:Dper_GL11125|serpin B - GO:0004866//endopeptidase inhibitor activity - 42981 2994.47 6.585 7.845 0.252590006711583 Up 0.286421872936204 CG11168 CG11168, isoform E K10380|1|1e-27|124|smm:Smp_145700|ankyrin - - - 5740868 857.00 0.05 0.065 0.37851162325373 Up 0.0544181746136574 CG34458 CG34458 K09640|1|3e-43|175|ecb:100146332|transmembrane protease, serine 9 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 19834887 764.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 33563 2885.00 10.795 11.89 0.139385471723151 Up 0.224838198388588 sec5 Sec5 ortholog - GO:0030135//coated vesicle;GO:0043234//protein complex;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005768//endosome;GO:0042995//cell projection GO:0016564//transcription repressor activity GO:0006952//defense response;GO:0006903//vesicle targeting;GO:0051301//cell division;GO:0001505//regulation of neurotransmitter levels;GO:0007281//germ cell development;GO:0016197//endosomal transport;GO:0006904//vesicle docking involved in exocytosis;GO:0035146 12798199 868.00 0.375 0.465 0.31034012061215 Up 0.0872077664773478 39835 6235.94 8.805 10.045 0.190082654902084 Up 0.262812045964866 CG43373 CG43373, isoform C K01768|1|0.0|1682|dme:Dmel_CG42513|adenylate cyclase [EC:4.6.1.1];K08045|5|1e-134|482|hsa:111|adenylate cyclase 5 [EC:4.6.1.1] GO:0031224//intrinsic to membrane GO:0016829//lyase activity;GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process 36741 2410.94 0.775 0.97 0.32378843691289 Up 0.124157971205917 Poxn Pox neuro, isoform B K09383|1|1e-41|171|mdo:100013303|paired box protein 2/5 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007472//wing disc morphogenesis;GO:0009628//response to abiotic stimulus;GO:0010468//regulation of gene expression;GO:0007478//leg disc morphogenesis;GO:0006351//transcription, DNA-dependent;GO:0007619//courtship behavior;GO:0007631//feeding behavior 32836 3415.41 12.445 8.83 -0.49508088733257 Down 0.495311055342755 GalNAc-T2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2, isoform C K00710|1|0.0|1218|dme:Dmel_CG6394|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic to membrane GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0009311//oligosaccharide metabolic process;GO:0009311//oligosaccharide metabolic process 12798438 682.00 0.48 1.75 1.86624861111117 Up 0.422236164311187 CG43218 CG43218 - - - - 3772265 595.00 0.59 0.01 -5.88264304936184 Down 0.392253335094439 His2B:CG33868 histone H2B K11252|1|1e-47|188|tca:656563|histone H2B GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 35762 1230.76 20.49 22.25 0.118885351729876 Up 0.240721172896579 Nup44A nucleoporin at 44A, isoform C K01840|1|3e-73|275|bmy:Bm1_18455|phosphomannomutase [EC:5.4.2.8];K14004|2|1e-34|147|tca:657583|protein transport protein SEC13 GO:0005643//nuclear pore;GO:0000776//kinetochore;GO:0005643//nuclear pore;GO:0000776//kinetochore;GO:0005643//nuclear pore;GO:0000776//kinetochore GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0006810//transport;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000070//mitotic sister chromatid segregation;GO:0006997//nucleus organization;GO:0006810//transport;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000070//mitotic sister chromatid segregation;GO:0006997//nucleus organization;GO:0006810//transport;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000070//mitotic sister chromatid segregation;GO:0006997//nucleus organization 170878 569.00 31.81 33.78 0.0866889562618724 Up 0.209351472724871 Obp83g Odorant-binding protein 83g - - GO:0005488//binding GO:0007600//sensory perception;GO:0051234//establishment of localization 35847 678.00 29.535 30.03 0.0239788629344397 Up 0.0829811121384229 Vps25 vacuolar protein sorting 25 K12189|1|2e-101|368|dme:Dmel_CG14750|ESCRT-II complex subunit VPS25 - - GO:0006915//apoptotic process;GO:0007219//Notch signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0010796//regulation of multivesicular body size;GO:0001894//tissue homeostasis;GO:0016192//vesicle-mediated transport;GO:0035090//maintenance of apical/basal cell polarity;GO:0048869//cellular developmental process 2768892 3234.99 23.55 26.99 0.196697916966706 Up 0.358109893012812 CG42271 CG42271, isoform C K01109|1|5e-84|311|dme:Dmel_CG42271|inositol polyphosphate-4-phosphatase [EC:3.1.3.66];K10270|2|1e-68|260|dsi:Dsim_GD15856|F-box and leucine-rich repeat protein 4 - GO:0034593//phosphatidylinositol bisphosphate phosphatase activity GO:0030384 40970 2372.84 7.7 4.03 -0.934078607054296 Down 0.551974640073966 mtg mind the gap, isoform H - - GO:0030247//polysaccharide binding GO:0006022 36336 3481.60 9.585 9.925 0.0502886703621694 Up 0.102100118874653 CG8841 CG8841, isoform C - - - - 34060 1262.00 1.245 0.78 -0.674599713205832 Down 0.215031039492801 Uro urate oxidase K00365|1|0.0|729|dme:Dmel_CG7171|urate oxidase [EC:1.7.3.3] GO:0042579//microbody GO:0016663//oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor GO:0009112 5740127 145.00 0.385 0.525 0.447458976971221 Up 0.110652489763572 37358 1802.00 0.36 0.335 -0.10383581098454 Down 0.0473847576277902 CG9993 CG9993 K01904|1|3e-41|169|tad:TRIADDRAFT_56202|4-coumarate--CoA ligase [EC:6.2.1.12];K01896|4|5e-26|119|gga:426992|medium-chain acyl-CoA synthetase [EC:6.2.1.2];K01897|5|4e-25|116|dme:Dmel_CG12512|long-chain acyl-CoA synthetase [EC:6.2.1.3] - - - 36362 3192.65 40.16 58.735 0.548461187687826 Up 0.630927222295602 Dyb Dystrobrevin-like, isoform I K10366|1|6e-46|186|bfo:BRAFLDRAFT_125744|dystrophin GO:0016010//dystrophin-associated glycoprotein complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016010//dystrophin-associated glycoprotein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding - 32438 862.00 1.025 1.24 0.274716210881429 Up 0.122110685510501 CG33177 CG33177 K00799|1|1e-32|138|dpo:Dpse_GA14506|glutathione S-transferase [EC:2.5.1.18];K05309|4|4e-19|93.6|phu:Phum_PHUM080470|prostaglandin-E synthase [EC:5.3.99.3] - - - 34419 909.62 165.575 161.655 -0.0345667274225697 Down 0.114317791573108 Ip259 intronic protein 259, isoform B K00914|1|5e-25|114|cfa:490477|phosphatidylinositol 3-kinase [EC:2.7.1.137] GO:0043231//intracellular membrane-bounded organelle - - 39395 1240.00 0.985 1.45 0.557857270558558 Up 0.212653546427156 CG11529 CG11529 K01310|1|3e-41|169|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K09634|5|5e-30|132|tgu:100220345|transmembrane protease, serine 3 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 318198 822.00 0.05 0.07 0.485426827170242 Up 0.0549134856690001 CG32762 CG32762, isoform B - - - GO:0019538//protein metabolic process 37705 1094.00 0.995 1.275 0.357728816315209 Up 0.150508519350152 CG30414 CG30414, isoform C K01362|1|5e-31|135|dpo:Dpse_GA18526| [EC:3.4.21.-];K01312|3|2e-25|116|dpo:Dpse_GA15903|trypsin [EC:3.4.21.4];K01344|4|3e-24|112|dre:393327|protein C (activated) [EC:3.4.21.69] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process 34849 653.00 0.43 0.685 0.671767328258429 Up 0.156815480121516 CG3473 CG3473, isoform B K10580|1|5e-84|310|dme:Dmel_CG3473|ubiquitin-conjugating enzyme E2 N [EC:6.3.2.19] - GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0008344//adult locomotory behavior;GO:0042461//photoreceptor cell development;GO:0032446//protein modification by small protein conjugation;GO:0007154//cell communication;GO:0048667//cell morphogenesis involved in neuron differentiation 38185 2535.80 56.94 54.475 -0.0638482017389965 Down 0.170122837141725 CG12004 CG12004, isoform D - - - - 37228 2667.30 171.51 196.705 0.197740933516701 Up 0.422170122837142 SdhA succinate dehydrogenase A, isoform C K00234|1|0.0|1302|dme:Dmel_CG17246|succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] - - - 19836138 332.00 0.265 0.45 0.763932641766476 Up 0.134361378945978 - CG44406 - - - - 39948 762.00 166.255 156.005 -0.0918054607137277 Down 0.239433364152688 CG7603 CG7603 - - - - 36454 2678.68 1.25 1.19 -0.0709665213541436 Down 0.0583476423193766 lat latheo, isoform B K02605|1|0.0|1313|dme:Dmel_CG4088|origin recognition complex subunit 3 GO:0000808//origin recognition complex GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0008306//associative learning;GO:0030537//larval behavior 64880 3215.49 24.1 20.84 -0.209677868838816 Down 0.361742174085326 chico chico, isoform C K07187|1|2e-121|437|dmo:Dmoj_GI10661|insulin receptor substrate GO:0043231//intracellular membrane-bounded organelle;GO:0042598;GO:0043231//intracellular membrane-bounded organelle;GO:0042598 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0035151//regulation of tube size, open tracheal system;GO:0016049//cell growth;GO:0060249//anatomical structure homeostasis;GO:0035264//multicellular organism growth;GO:0042078//germ-line stem cell division;GO:0010259//multicellular organismal aging;GO:0032989;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0007028//cytoplasm organization;GO:0006950//response to stress;GO:0035151//regulation of tube size, open tracheal system;GO:0016049//cell growth;GO:0060249//anatomical structure homeostasis;GO:0035264//multicellular organism growth;GO:0042078//germ-line stem cell division;GO:0010259//multicellular organismal aging;GO:0032989;GO:0007292//female gamete generation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045927//positive regulation of growth;GO:0007028//cytoplasm organization;GO:0006950//response to stress 42739 1233.00 0.16 0.145 -0.142019004872428 Down 0.049861312904504 VhaAC39-2 vacuolar H[+] ATPase AC39 subunit 2 K02146|1|2e-92|339|tca:663777|V-type H+-transporting ATPase subunit AC39 [EC:3.6.3.14] GO:0033176 GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006810//transport;GO:0006754//ATP biosynthetic process 43603 607.00 4.62 0.745 -2.6325805209539 Down 0.635318980319641 CG18404 CG18404 - - - - 33162 1637.58 74.54 78.67 0.0777987645372453 Up 0.210540219257694 galectin galectin, isoform F K10093|1|7e-29|129|ecb:100058771|galectin-9 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0048029//monosaccharide binding;GO:0048029//monosaccharide binding;GO:0048029//monosaccharide binding - 42236 6098.00 0.58 1.365 1.23477614579228 Up 0.319376568485009 qin qin - - GO:0005488//binding - 41973 3797.00 3.835 3.265 -0.232143585956503 Down 0.19300620789856 Mat89Ba maternal transcript 89Ba - - - - 318662 1834.00 4.245 1.77 -1.26201519347004 Down 0.513934751023643 CG31286 CG31286 K01940|1|6e-163|574|dme:Dmel_CG1315|argininosuccinate synthase [EC:6.3.4.5] GO:0044424//intracellular part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032559 GO:0006525//arginine metabolic process;GO:0019627//urea metabolic process 43192 1392.00 26.79 21.835 -0.295052050062124 Down 0.457733456610752 CG5447 CG5447, isoform B - - - - 43348 1007.00 8.955 9.08 0.0199988653049534 Up 0.0611544049663188 CG4980 BCAS2 ortholog K12861|1|6e-137|486|dme:Dmel_CG4980|pre-mRNA-splicing factor SPF27 GO:0005681//spliceosomal complex - GO:0000377 37344 2566.22 59.395 32.135 -0.886196014563649 Down 0.697497028133668 Fem-1 Fem-1, isoform B K10349|1|0.0|1263|dse:Dsec_GM19767|Fem-1 homolog b - - - 36209 1465.00 17.36 11.4 -0.606733123392375 Down 0.572513538502179 Fpps farnesyl pyrophosphate synthase K00787|1|0.0|841|dme:Dmel_CG12389|farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] - GO:0004659//prenyltransferase activity GO:0007276//gamete generation;GO:0006720//isoprenoid metabolic process;GO:0008654//phospholipid biosynthetic process 35425 3225.58 21.78 23.04 0.0811367627254052 Up 0.180623431514991 step steppke, isoform E K12495|1|2e-39|165|bfo:BRAFLDRAFT_106693|IQ motif and SEC7 domain-containing protein GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity;GO:0005083//small GTPase regulator activity GO:0035264//multicellular organism growth;GO:0032011//ARF protein signal transduction;GO:0035264//multicellular organism growth;GO:0032011//ARF protein signal transduction;GO:0035264//multicellular organism growth;GO:0032011//ARF protein signal transduction 246573 610.00 40.68 50.63 0.315672805052311 Up 0.5134394399683 CG30373 CG30373, isoform B - - - - 37507 823.00 0.475 0.645 0.441371647092306 Up 0.120492669396381 CG9308 CG9308 K01529|1|2e-36|152|mcc:709884| [EC:3.6.1.-];K05409|2|4e-13|75.1|mdo:100029323|TRIF-related adaptor molecule GO:0031224//intrinsic to membrane;GO:0030137//COPI-coated vesicle;GO:0030667//secretory granule membrane;GO:0042598 - GO:0009987//cellular process;GO:0006810//transport 36491 4117.32 28.225 24.55 -0.201250556458308 Down 0.363029982829217 cnn centrosomin, isoform N K01509|1|6e-59|228|dpo:Dpse_GA18464|adenosinetriphosphatase [EC:3.6.1.3];K04648|2|5e-10|66.2|tgu:100230170|dynactin 1;K10421|4|1e-09|64.7|tgu:100219895|CAP-Gly domain-containing linker protein 1;K06674|5|2e-09|63.9|gga:396156|structural maintenance of chromosome 2 GO:0005813//centrosome;GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0015629//actin cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0048565//digestive tract development;GO:0048285;GO:0045165//cell fate commitment;GO:0007143//female meiosis;GO:0007399//nervous system development;GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0048565//digestive tract development;GO:0048285;GO:0045165//cell fate commitment;GO:0007143//female meiosis;GO:0007399//nervous system development;GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0048565//digestive tract development;GO:0048285;GO:0045165//cell fate commitment;GO:0007143//female meiosis;GO:0007399//nervous system development;GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0048565//digestive tract development;GO:0048285;GO:0045165//cell fate commitment;GO:0007143//female meiosis;GO:0007399//nervous system development;GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0048565//digestive tract development;GO:0048285;GO:0045165//cell fate commitment;GO:0007143//female meiosis;GO:0007399//nervous system development;GO:0000278//mitotic cell cycle;GO:0031023//microtubule organizing center organization;GO:0048565//digestive tract development;GO:0048285;GO:0045165//cell fate commitment;GO:0007143//female meiosis;GO:0007399//nervous system development 43476 3457.13 17.61 20.025 0.185407333464864 Up 0.324758948619733 Trc8 Trc8, isoform E K10601|1|8e-12|73.6|dre:335226|E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007417//central nervous system development;GO:0040008//regulation of growth;GO:0007417//central nervous system development;GO:0040008//regulation of growth;GO:0007417//central nervous system development;GO:0040008//regulation of growth 36012 1439.00 3.775 4.03 0.0943031943155263 Up 0.103751155725796 CG1663 CG1663 K09228|1|4e-23|109|ecb:100065331|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 19834761 1490.00 1.975 1.83 -0.110009004780423 Down 0.0833443402456743 - CG44249 - - - - 42540 751.00 0.325 0.55 0.758991900496205 Up 0.15222559767534 CheB93a chemosensory protein B 93a - - - - 33232 2725.70 5.8 5.365 -0.112474729258413 Down 0.141229692246731 CG11835 CG11835, isoform D K01527|1|7e-46|186|tca:656401|nascent polypeptide-associated complex subunit beta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton - GO:0044087 42990 10305.64 5.34 4.765 -0.164363527777612 Down 0.177123233390569 tnc tenectin, isoform D - - - - 12798330 2621.48 4.275 3.48 -0.296837113924532 Down 0.247094175141989 CG43110 CG43110, isoform B - - - - 4379856 748.00 1.53 1.56 0.0280143761695965 Up 0.0473517368907674 CG34138 CG34138 - - - - 32662 973.00 29.67 27.605 -0.104075325688328 Down 0.224772156914542 mRpL22 mitochondrial ribosomal protein L22 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 59164 1804.00 0.125 0.17 0.443606651475615 Up 0.0738343679830934 CG18788 CG18788 K08193|1|5e-71|268|dpo:Dpse_GA18795|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), other - - GO:0006810//transport 3772451 543.00 0.08 0.17 1.08746284125034 Up 0.103057720248316 CG33723 CG33723 K09255|1|4e-23|107|dpe:Dper_GL18753|Rel/ankyrin family, other;K12602|2|6e-12|70.1|dpo:Dpse_GA17766|WD repeat-containing protein 61 GO:0032991//macromolecular complex GO:0000166//nucleotide binding GO:0007017//microtubule-based process 35257 1034.00 7.82 7.71 -0.0204377473923183 Down 0.0598335754854048 CG10262 CG10262 K04802|1|9e-137|485|dme:Dmel_CG10262|proliferating cell nuclear antigen GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0030234//enzyme regulator activity GO:0006260//DNA replication 31235 1152.77 22.24 15.86 -0.487764017019529 Down 0.553724739136177 Vha36-3 vacuolar H[+] ATPase 36kD subunit 3, isoform C K02149|1|1e-126|452|dme:Dmel_CG8310|V-type H+-transporting ATPase subunit D [EC:3.6.3.14] - - - 35207 2630.00 5.62 4.835 -0.217054240744085 Down 0.223847576277903 dnt doughnut on 2, isoform B K05128|1|0.0|1118|dme:Dmel_CG17559|RYK receptor-like tyrosine kinase [EC:2.7.10.1] GO:0016021//integral to membrane GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0032559 GO:0023060;GO:0006935//chemotaxis;GO:0007431//salivary gland development;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process 39434 2202.00 15.35 12.375 -0.310810130403208 Down 0.416325452384097 nst nesthocker K01836|1|0.0|1088|dme:Dmel_CG10627|phosphoacetylglucosamine mutase [EC:5.4.2.3] GO:0044444//cytoplasmic part GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0046872//metal ion binding GO:0006045//N-acetylglucosamine biosynthetic process;GO:0009416//response to light stimulus;GO:0006290//pyrimidine dimer repair;GO:0006023;GO:0006006//glucose metabolic process;GO:0009790//embryo development 19835571 310.00 0.295 0.01 -4.88264304936184 Down 0.269251089684322 - CG45079 - - - - 38006 2741.47 86.38 78.835 -0.131861038184235 Down 0.306036190727777 gol goliath, isoform E K10629|1|4e-40|166|gga:422382|E3 ubiquitin-protein ligase RNF128 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development;GO:0006351//transcription, DNA-dependent;GO:0009888//tissue development 33735 438.00 0.575 0.325 -0.823122237915921 Down 0.161504424778761 CG14036 CG14036 K02728|1|8e-07|52.0|ame:413757|20S proteasome subunit alpha 3 [EC:3.4.25.1] - - - 45879 6043.00 1.24 0.84 -0.561878887608115 Down 0.194954431382908 ImpE1 Ecdysone-inducible gene E1, isoform C K04550|1|4e-27|125|spu:582052|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) GO:0044425//membrane part GO:0005488//binding - 41407 1123.00 97.795 69.825 -0.486017037371627 Down 0.624818385946374 Ho heme oxygenase K00510|1|4e-146|517|dme:Dmel_CG14716|heme oxygenase [EC:1.14.99.3] - GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0006787 48422 1532.03 25.43 26.05 0.0347519104757645 Up 0.100184916127328 CG5707 CG5707, isoform C K01175|1|1e-21|104|mmu:68607| [EC:3.1.-.-] - - - 32767 817.00 2.13 1.57 -0.440088871334211 Down 0.223781534803857 CG32554 CG32554 - - - - 43281 1447.00 2.335 2.1 -0.153033222043539 Down 0.111411966715097 CG5984 CG5984 K04437|1|1e-105|382|dpo:Dpse_GA19276|filamin - - - 37289 3552.74 21.9 21.765 -0.00892084970063498 Down 0.0570268128384626 CG11055 Hormone-sensitive lipase ortholog, isoform C K07188|1|6e-110|399|spu:585712|hormone-sensitive lipase [EC:3.1.1.79] - - - 35430 4732.00 3.475 2.905 -0.258474814206341 Down 0.198784836877559 tsh teashirt K09236|1|0.0|1382|dme:Dmel_CG1374|teashirt GO:0043231//intracellular membrane-bounded organelle GO:0003702//RNA polymerase II transcription factor activity;GO:0005488//binding GO:0035292//specification of segmental identity, trunk;GO:0045704;GO:0048729//tissue morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007478//leg disc morphogenesis;GO:0007449//proximal/distal pattern formation, imaginal disc;GO:0001700//embryonic development via the syncytial blastoderm;GO:0001654//eye development;GO:0007472//wing disc morphogenesis 38753 1929.77 117.74 64.745 -0.862763844175506 Down 0.708162726192049 Prat2 phosphoribosylamidotransferase 2, isoform B K00764|1|0.0|955|dya:Dyak_GE20462|amidophosphoribosyltransferase [EC:2.4.2.14] - GO:0016763//transferase activity, transferring pentosyl groups;GO:0043169//cation binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0043169//cation binding GO:0006144//purine nucleobase metabolic process;GO:0006163//purine nucleotide metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006163//purine nucleotide metabolic process 7354428 5111.00 9.105 9.655 0.0846172419738121 Up 0.140106987187954 CG42245 CG42245 - GO:0044464//cell part GO:0046914//transition metal ion binding;GO:0016887//ATPase activity GO:0048812//neuron projection morphogenesis 318149 897.00 0.01 0.1 3.32192809488736 Up 0.129177123233391 Rab9D Rab at 9D K07976|1|6e-113|406|dme:Dmel_CG32678|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 39023 3148.00 4.58 4.615 0.0109830495488303 Up 0.0472856954167217 CG5660 CG5660, isoform B K01873|1|0.0|2008|dme:Dmel_CG5660|valyl-tRNA synthetase [EC:6.1.1.9] GO:0044424//intracellular part GO:0004812//aminoacyl-tRNA ligase activity;GO:0032559 GO:0006418//tRNA aminoacylation for protein translation 41104 1468.00 198.065 191.87 -0.0458448092569924 Down 0.157541936336019 VhaM8.9 vacuolar H[+] ATPase M8.9 accessory subunit - GO:0031224//intrinsic to membrane GO:0004871//signal transducer activity - 117473 1161.00 0.04 0.08 1 Up 0.0725795799762251 Gr92a gustatory receptor 92a K08471|1|0.0|755|dme:Dmel_CG31208|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 43456 642.00 4.05 7.17 0.824051210929918 Up 0.518788799366002 Mesh1 metazoan SpoT homolog-1 - - - - 50251 966.00 11.475 14.07 0.294128174935363 Up 0.390932505613525 CG17977 CG17977 - - - - 3772370 529.00 0.01 0.01 0 - 0.0382380134724607 His3:CG33821 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 33703 875.00 49.42 57.03 0.206626022040924 Up 0.407112666754722 mRpL24 mitochondrial ribosomal protein L24 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 33204 6975.57 42.51 49.405 0.21685479720887 Up 0.412759212785629 Plc21C phospholipase C at 21C, isoform H K05858|1|0.0|2307|dsi:Dsim_GD23017|phospholipase C, beta [EC:3.1.4.11] - GO:0060089;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity;GO:0060089;GO:0046872//metal ion binding;GO:0004629//phospholipase C activity GO:0046488//phosphatidylinositol metabolic process;GO:0008344//adult locomotory behavior;GO:0046339//diacylglycerol metabolic process;GO:0023033;GO:0023060;GO:0046488//phosphatidylinositol metabolic process;GO:0008344//adult locomotory behavior;GO:0046339//diacylglycerol metabolic process;GO:0023033;GO:0023060;GO:0046488//phosphatidylinositol metabolic process;GO:0008344//adult locomotory behavior;GO:0046339//diacylglycerol metabolic process;GO:0023033;GO:0023060;GO:0046488//phosphatidylinositol metabolic process;GO:0008344//adult locomotory behavior;GO:0046339//diacylglycerol metabolic process;GO:0023033;GO:0023060;GO:0046488//phosphatidylinositol metabolic process;GO:0008344//adult locomotory behavior;GO:0046339//diacylglycerol metabolic process;GO:0023033;GO:0023060 35096 2846.64 19.075 22.235 0.221149347629615 Up 0.367322678642187 Acp36DE accessory gland protein 36DE, isoform B - - - GO:0019098//reproductive behavior;GO:0046692//sperm competition 32967 1679.00 39.515 41.385 0.0667075492438243 Up 0.18002905824858 CG12237 CG12237 K01112|1|7e-126|451|dpo:Dpse_GA11499| [EC:3.1.3.-];K13248|2|4e-41|169|bta:507308|pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74] - GO:0042578//phosphoric ester hydrolase activity - 31855 952.00 15.715 17.205 0.13068561993823 Up 0.240655131422533 CG12056 CG12056 - - GO:0005506//iron ion binding - 40190 1519.84 32.96 27.395 -0.266803638877239 Down 0.443369436005812 CG7668 CG7668, isoform C K10104|1|3e-23|109|bfo:BRAFLDRAFT_252169|ficolin;K06252|4|5e-22|105|dre:369191|tenascin - GO:0005515//protein binding;GO:0005515//protein binding GO:0023060;GO:0023060 19836158 856.00 2.89 2.06 -0.488425155317461 Down 0.277605336151103 31566 1463.00 14.64 14.615 -0.00246572447798977 Down 0.0427618544445912 wuho wuho K10751|1|5e-06|52.8|api:100164361|chromatin assembly factor 1 subunit B;K01062|2|8e-06|52.0|phu:Phum_PHUM438100|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] - - - 31472 1691.00 0.315 1.12 1.83007499855769 Up 0.34278827103421 CG34434 CG34434 - - GO:0046872//metal ion binding - 32476 1272.37 10.97 14.565 0.408942175737156 Up 0.472031435741646 CG15642 CG15642, isoform B K08051|1|1e-48|193|dpo:Dpse_GA19499|pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 GO:0044424//intracellular part GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0006869//lipid transport 2768905 607.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 Ste:CG33246 Ste:CG33246 K08282|1|2e-95|347|dme:Dmel_CG33246|non-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0004672//protein kinase activity GO:0048232//male gamete generation;GO:0043549//regulation of kinase activity 37146 4622.12 26.78 28.585 0.0941023296094431 Up 0.206280544181746 CG30122 CG30122, isoform D K05115|1|7e-41|170|mcc:706123|AXL receptor tyrosine kinase [EC:2.7.10.1];K12888|3|9e-37|156|oaa:100082929|heterogeneous nuclear ribonucleoprotein U GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - GO:0000377;GO:0000377 36173 1573.16 73.05 75.575 0.0490248008242084 Up 0.151730286619997 Syx7 syntaxin 7, isoform B K08488|1|5e-97|355|dme:Dmel_CG5081|syntaxin 7 GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0006906//vesicle fusion;GO:0001505//regulation of neurotransmitter levels;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0042127//regulation of cell proliferation;GO:0030100//regulation of endocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0006906//vesicle fusion;GO:0001505//regulation of neurotransmitter levels;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0042127//regulation of cell proliferation;GO:0030100//regulation of endocytosis;GO:0006904//vesicle docking involved in exocytosis 40185 1028.00 28.02 7.25 -1.95040405552852 Down 0.749240523048474 fln flightin, isoform B - GO:0005859//muscle myosin complex - GO:0014866//skeletal myofibril assembly 33645 606.00 20.665 18.12 -0.189606408328305 Down 0.328820499273544 Dim1 Dim1 K12859|1|2e-81|300|dvi:Dvir_GJ19964|U5 snRNP protein, DIM1 family GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex GO:0005488//binding GO:0000087//M phase of mitotic cell cycle;GO:0000398//mRNA splicing, via spliceosome 246460 552.00 2.785 2.34 -0.251168797756627 Down 0.173358869369964 CG30108 CG30108 - - - - 19835622 3939.36 0.855 1.475 0.786718629363306 Up 0.262250693435477 - CG44435, isoform B - - - - 34914 789.00 0.6 0.505 -0.248679112856724 Down 0.082089552238806 CG11864 CG11864 K08076|1|2e-31|135|cel:F09E8.6|astacin [EC:3.4.24.21];K08606|3|9e-28|123|tgu:100227825|meprin A, beta [EC:3.4.24.18] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 31957 3872.29 57.335 55.275 -0.0527889772518426 Down 0.149716021661603 alpha-Man-I alpha mannosidase I, isoform P K01230|1|0.0|1120|dan:Dana_GF22633|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924;GO:0046872//metal ion binding;GO:0015924 GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation;GO:0010259//multicellular organismal aging;GO:0050896//response to stimulus;GO:0006486//protein glycosylation 31657 1819.00 7.755 10.055 0.374714395269261 Up 0.405428609166557 CG4617 CG4617, isoform C K11298|1|0.0|726|dme:Dmel_CG4617|high mobility group protein 2-like 1 - - - 40842 3191.62 21.715 27.02 0.315335721871792 Up 0.475168405758817 CG1965 CG1965, isoform C K13211|1|0.0|1497|dme:Dmel_CG1965|GC-rich sequence DNA-binding factor GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0000377 3885628 1821.00 2.835 3.51 0.308122295362332 Up 0.228437458724079 Ir62a ionotropic receptor 62a - - - - 19834834 221.00 0.24 2.81 3.54946381949977 Up 0.59800554748382 33032 591.00 0.15 0.155 0.0473057147783568 Up 0.0419363360190199 CG15460 jean-baptiste - - - - 33956 1074.02 0.83 0.72 -0.205114429904612 Down 0.0858208955223881 CG17375 CG17375, isoform D - - - - 37015 1699.00 14.965 10.08 -0.570096639998184 Down 0.544511953506802 Snx16 sorting nexin 16 K08792|1|2e-14|80.5|hmg:100215651|serum/glucocorticoid-regulated kinase, invertebrate [EC:2.7.11.1];K13304|2|1e-13|78.2|tgu:100231693|serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1] - - - 40073 3030.05 107.44 102.485 -0.0681184417005751 Down 0.194756306960771 CG18135 CG18135, isoform E - - GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0005488//binding;GO:0004620//phospholipase activity;GO:0008081//phosphoric diester hydrolase activity GO:0023033;GO:0019400;GO:0023033;GO:0019400;GO:0023033;GO:0019400;GO:0023033;GO:0019400 43244 1634.00 34.6 27.2 -0.347165386386385 Down 0.51367058512746 CG31075 CG31075, isoform B K00128|1|0.0|924|dme:Dmel_CG31075|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] - GO:0003824//catalytic activity GO:0008152//metabolic process 31664 2105.49 36.21 36.985 0.0305520989714965 Up 0.103751155725796 unc-119 unc-119, isoform C - - - - 39016 5230.52 0.035 0.145 2.05062607306997 Up 0.120855897503632 mfr misfire, isoform J - - - GO:0003002//regionalization;GO:0007338//single fertilization;GO:0003002//regionalization;GO:0007338//single fertilization;GO:0003002//regionalization;GO:0007338//single fertilization;GO:0003002//regionalization;GO:0007338//single fertilization;GO:0003002//regionalization;GO:0007338//single fertilization;GO:0003002//regionalization;GO:0007338//single fertilization;GO:0003002//regionalization;GO:0007338//single fertilization 14462812 437.00 0.11 0.135 0.295455883526171 Up 0.0597675340113591 50392 2316.69 38.22 28.225 -0.437354197317093 Down 0.570532294280808 schlank schlank, isoform B K14010|1|3e-11|70.9|isc:IscW_ISCW000550|translocating chain-associated membrane protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 117347 1110.00 0.155 0.085 -0.866733469136536 Down 0.0881983885880333 Gr39b gustatory receptor 39b K08471|1|0.0|705|dme:Dmel_CG31620|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 43399 3932.89 24.66 28.515 0.209548232966869 Up 0.37349755646546 CG1646 CG1646, isoform H K13217|1|0.0|1508|dme:Dmel_CG1646|pre-mRNA-processing factor 39 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 43701 1101.00 0.425 0.01 -5.4093909361377 Down 0.330372473913618 CG3669 CG3669 K01672|1|2e-172|604|dme:Dmel_CG3669|carbonic anhydrase [EC:4.2.1.1] - GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process 31314 1758.00 0.11 0.22 1 Up 0.112336547351737 CG10801 CG10801, isoform B K10445|1|2e-10|67.8|dre:393851|kelch-like protein 7 - - - 41834 2986.00 13.195 12.84 -0.0393461482039653 Down 0.0987650244353454 CG12241 CG12241 K11247|1|1e-08|62.8|xla:432228|endophilin-A;K04364|4|3e-08|61.2|bmy:Bm1_39900|growth factor receptor-binding protein 2 - - - 38402 1260.05 8.55 5.4 -0.662965012722429 Down 0.501485933166028 ckd cracked, isoform E - - GO:0030247//polysaccharide binding GO:0006022 5740681 723.00 0.33 0.555 0.750021746991653 Up 0.152159556201294 CG34432 CG34432 - - - - 35352 1020.00 1.365 1.06 -0.364836686356653 Down 0.156353189803196 CG14402 CG14402, isoform B - - - - 41173 1120.00 135.235 125.185 -0.111406876966424 Down 0.277143045832783 CG16817 CG16817, isoform B - - - - 41987 1010.72 1.965 1.79 -0.13456972499435 Down 0.0967507594769515 CG10317 CG10317, isoform D - - - - 13084068 1540.96 0.21 0.035 -2.58496250072116 Down 0.164476291110818 CG43355 CG43355, isoform C - - - - 34933 1421.00 1.13 1.52 0.427748551028398 Up 0.184684982168802 CG13243 CG13243, isoform B - - GO:0019887//protein kinase regulator activity GO:0023060 43713 1488.59 13.33 15.825 0.247528719226731 Up 0.3632941487254 CG11334 CG11334, isoform C K03239|1|8e-11|68.6|dre:415150|translation initiation factor eIF-2B alpha subunit - GO:0008135//translation factor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding GO:0010467//gene expression;GO:0009058//biosynthetic process;GO:0010467//gene expression;GO:0009058//biosynthetic process 35277 6053.74 20.29 22.775 0.166682188932754 Up 0.31105534275525 sick sickie, isoform N K11653|1|4e-06|54.7|dgr:Dgri_GH15872|AT-rich interactive domain-containing protein 1 - GO:0016462//pyrophosphatase activity;GO:0032559;GO:0000166//nucleotide binding;GO:0016462//pyrophosphatase activity;GO:0032559;GO:0016462//pyrophosphatase activity;GO:0032559 GO:0042742//defense response to bacterium;GO:0042742//defense response to bacterium;GO:0042742//defense response to bacterium 2768882 1329.00 7.46 8.105 0.119636555262304 Up 0.172170122837142 CG9125 CG9125 - - - - 8673993 954.51 145.295 197.935 0.44604168381386 Up 0.621153084136838 CG42508 CG42508, isoform B - - - - 326199 616.00 10.405 12.535 0.268685031098605 Up 0.357152291639149 CG32202 CG32202 - - - - 53471 2050.97 22.285 31.075 0.479681430327193 Up 0.574891031567825 SP555 SP555, isoform D K10345|1|8e-151|534|dsi:Dsim_GD12021|SPRY domain-containing SOCS box protein 3 - - GO:0023033;GO:0023033 39230 1374.00 0.01 0.035 1.8073549220576 Up 0.0591731607449478 CG32079 CG32079 K08653|1|5e-07|55.8|tgu:100232413|membrane-bound transcription factor protease, site 1 [EC:3.4.21.-] GO:0031224//intrinsic to membrane - - 32130 4075.00 0.105 0.06 -0.807354922057604 Down 0.0697397965922599 dy dusky - GO:0031224//intrinsic to membrane GO:0042302//structural constituent of cuticle GO:0007472//wing disc morphogenesis;GO:0032989;GO:0048511//rhythmic process;GO:0007610//behavior 32212 2001.76 8.85 7.485 -0.241675138911943 Down 0.2926297714965 CG2543 CG2543, isoform B K01930|1|0.0|1110|dme:Dmel_CG2543|folylpolyglutamate synthase [EC:6.3.2.17] - GO:0016881//acid-amino acid ligase activity;GO:0032559 GO:0006760//folic acid-containing compound metabolic process 40308 1679.00 16.435 13.465 -0.287557226578638 Down 0.405626733588694 CSN3 COP9 complex homolog subunit 3 K12177|1|0.0|827|dme:Dmel_CG18332|COP9 signalosome complex subunit 3 GO:0043234//protein complex - GO:0031647//regulation of protein stability 40640 2786.00 37.485 33.35 -0.168626640735913 Down 0.340047549861313 Cerk ceramide kinase, isoform B K04715|1|4e-77|290|cfa:474464|ceramide kinase [EC:2.7.1.138] - GO:0016301//kinase activity;GO:0016301//kinase activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway 318097 48733.00 0.02 0.03 0.584962500721156 Up 0.047450799101836 Muc14A mucin 14A K10955|1|4e-59|234|hsa:4583|intestinal mucin-2 - - - 33305 3540.43 15.3 19.16 0.324565908156166 Up 0.447530048870691 CG4896 CG4896, isoform K K13094|1|0.0|1581|dme:Dmel_CG4896|RNA-binding protein 5/10 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0000377;GO:0000377 33111 1021.00 19.41 21.09 0.119758977080028 Up 0.2377162858275 dod dodo K09578|1|4e-80|298|dme:Dmel_CG17051|peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway 43186 2981.66 55.205 34.48 -0.679039165556993 Down 0.659688284242504 CG33970 CG33970, isoform C K05643|1|2e-27|125|spu:586285|ATP-binding cassette, subfamily A (ABC1), member 3;K05644|3|7e-27|123|xla:497268|ATP-binding cassette, subfamily A (ABC1), member 4 GO:0043234//protein complex;GO:0044464//cell part;GO:0043234//protein complex;GO:0044464//cell part GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0051234//establishment of localization;GO:0051234//establishment of localization 19835229 761.00 0.01 0.185 4.20945336562895 Up 0.199412230880993 32711 788.00 589.2 205.835 -1.51726911270368 Down 0.772189935279355 CG5172 CG5172, isoform D - - - - 42638 2417.31 21.485 19.225 -0.160346178924749 Down 0.294875181614054 CG34376 CG34376, isoform B K02174|1|6e-28|126|dme:Dmel_CG11491|broad;K09237|2|6e-26|119|nvi:100122117|Cys2His2 zinc finger developmental/cell cycle regulator, other - - - 318558 1980.00 0.88 1.195 0.441435189343451 Up 0.164410249636772 CG31019 CG31019, isoform B K02999|1|4e-08|60.1|spu:590155|DNA-directed RNA polymerase I subunit A1 [EC:2.7.7.6] - GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process 43001 883.73 12.9 18.555 0.524436935386909 Up 0.54969620921939 CG31109 CG31109, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 43159 1137.00 0.1 0.155 0.632268215499513 Up 0.075023114515916 E(spl)m6-BFM enhancer of split m6, bearded family member - - - - 31977 2098.00 11.735 12.5 0.0911102530262792 Up 0.165499933958526 CG2889 CG2889, isoform B K09228|1|4e-32|140|rno:367033|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 37264 547.00 25.92 27.29 0.0743066763895157 Up 0.171047417778365 Obp56a Odorant-binding protein 56a - - - - 32706 465.00 0.985 0.01 -6.62205181945638 Down 0.498910315678246 CG32563 CG32563, isoform B - - - - 41829 1431.00 9.365 12.92 0.46425517045088 Up 0.485272751287809 Spn88Eb serpin 88Eb K13963|1|7e-50|198|cin:100182186|serpin B - - - 36821 2833.00 23.855 15.595 -0.613208133610153 Down 0.600316999075419 Atg9 Autophagy-specific gene 9, isoform B - - - - 37892 5405.64 16.69 21.165 0.342696533955822 Up 0.469951129309206 mAcR-60C muscarinic acetylcholine Receptor, A-type, isoform B K04131|1|0.0|1174|dsi:Dsim_GD24962|muscarinic acetylcholine receptor M3 GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0016907//G-protein coupled acetylcholine receptor activity;GO:0016907//G-protein coupled acetylcholine receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0023060;GO:0007186//G-protein coupled receptor signaling pathway 38393 850.00 0.245 0.01 -4.61470984411521 Down 0.239499405626734 CG32277 CG32277 K01312|1|6e-28|124|bfo:BRAFLDRAFT_88359|trypsin [EC:3.4.21.4];K09635|2|2e-27|122|gga:770454|transmembrane protease, serine 4 [EC:3.4.21.-];K09463|5|5e-27|121|ecb:100067063|kallikrein 13 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 43522 976.00 68.07 116.29 0.772636027188999 Up 0.696506406022982 CG7829 CG7829 K01312|1|2e-43|176|dpo:Dpse_GA21879|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32326 1294.85 25.48 23.1 -0.14147242595288 Down 0.279982829216748 CG12177 CG12177, isoform C K01239|1|1e-30|134|xla:379157|purine nucleosidase [EC:3.2.2.1] - - - 19835463 437.00 3.645 3.425 -0.0898148264790482 Down 0.0958591995773346 41256 7494.21 15.325 14.835 -0.0468821470978768 Down 0.115407475894862 CG43143 CG43143, isoform I K08800|1|4e-98|360|dre:561563|NUAK family, SNF1-like kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 3772225 1023.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 His1:CG33840 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 19835318 734.00 0.06 0.08 0.415037499278844 Up 0.0547483819838859 31788 1112.00 0.01 0.08 3 Up 0.110718531237617 Cp38 chorion protein 38, isoform B - - - - 34119 1023.69 41.31 42.385 0.0370627268958124 Up 0.124224012679963 Su(var)205 suppressor of variegation 205, isoform B K11587|1|3e-79|295|dme:Dmel_CG8409|chromobox protein 5;K11585|2|3e-75|281|dya:Dyak_GE11133|chromobox protein 1 GO:0000781//chromosome, telomeric region;GO:0005700//polytene chromosome;GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0000790//nuclear chromatin;GO:0000781//chromosome, telomeric region;GO:0005700//polytene chromosome;GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0000790//nuclear chromatin GO:0030528//transcription regulator activity;GO:0042393//histone binding;GO:0043565//sequence-specific DNA binding;GO:0003723//RNA binding;GO:0030528//transcription regulator activity;GO:0042393//histone binding;GO:0043565//sequence-specific DNA binding;GO:0003723//RNA binding GO:0016571//histone methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006342//chromatin silencing;GO:0006915//apoptotic process;GO:0006338//chromatin remodeling;GO:0044030//regulation of DNA methylation;GO:0016571//histone methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006342//chromatin silencing;GO:0006915//apoptotic process;GO:0006338//chromatin remodeling;GO:0044030//regulation of DNA methylation 33140 3123.68 18.485 21 0.184034284366242 Up 0.319871879540351 CG17598 CG17598, isoform B K01090|1|2e-85|317|xtr:550059|protein phosphatase [EC:3.1.3.16] GO:0043234//protein complex GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0006464//cellular protein modification process 38545 2091.07 136.715 228.2 0.739127251400943 Up 0.701294412891296 nAcRbeta-64B nicotinic acetylcholine receptor beta1, isoform B K05312|1|0.0|1019|dme:Dmel_CG11348|nicotinic acetylcholine receptor, invertebrate GO:0005887//integral to plasma membrane;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0006810//transport 19835357 935.79 0.92 0.675 -0.446746359006182 Down 0.142946770571919 12798520 1332.00 0.325 1.475 2.18220333122075 Up 0.411702549200898 35131 1581.02 12.53 14.09 0.169285196987776 Up 0.27304847444195 Irk3 inwardly rectifying potassium channel 3, isoform D K05330|1|4e-51|202|cel:R03E9.4|potassium inwardly-rectifying channel subfamily J, invertebrate;K05005|3|1e-48|194|cfa:403760|potassium inwardly-rectifying channel subfamily J member 12 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005249//voltage-gated potassium channel activity;GO:0005249//voltage-gated potassium channel activity GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport;GO:0006873//cellular ion homeostasis;GO:0030001//metal ion transport 35419 5011.34 40.65 46.605 0.197229389880607 Up 0.387729494122309 Ac3 Ac3, isoform C K08043|1|0.0|1926|dse:Dsec_GM16140|adenylate cyclase 3 [EC:4.6.1.1] GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0005488//binding;GO:0009975//cyclase activity;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0016829//lyase activity GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0023033;GO:0009124//nucleoside monophosphate biosynthetic process 39493 4825.50 26.26 25.225 -0.058012646899167 Down 0.150871747457403 caps capricious, isoform D K13023|1|5e-35|150|mcc:707574|carboxypeptidase N regulatory subunit GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007411//axon guidance;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0007270//neuron-neuron synaptic transmission;GO:0006887//exocytosis;GO:0035146;GO:0007411//axon guidance;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0007270//neuron-neuron synaptic transmission;GO:0006887//exocytosis;GO:0035146;GO:0007411//axon guidance;GO:0048870//cell motility;GO:0060541//respiratory system development;GO:0007270//neuron-neuron synaptic transmission;GO:0006887//exocytosis;GO:0035146 19836131 427.00 0.01 0.555 5.79441586635011 Up 0.38171971998415 37978 1349.00 8.54 10.335 0.275230413804957 Up 0.342590146612072 Atf-2 activating transcription factor-2 K04450|1|2e-09|63.5|dre:100006516|activating transcription factor 2 GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0000165//MAPK cascade;GO:0006970//response to osmotic stress;GO:0019432//triglyceride biosynthetic process;GO:0002251;GO:0007610//behavior;GO:0010551 31623 1640.00 4.76 5.85 0.297475051162823 Up 0.285695416721701 CG4542 xiantuan K03849|1|0.0|812|dme:Dmel_CG4542|alpha-1,3-glucosyltransferase [EC:2.4.1.-] - - - 3772540 769.00 9.69 8.83 -0.134083227766615 Down 0.19914806498481 CG33635 CG33635 - - GO:0005488//binding GO:0006892//post-Golgi vesicle-mediated transport 37751 1923.97 22.175 23.435 0.0797306902905981 Up 0.180623431514991 CG4091 CG4091, isoform C - GO:0044424//intracellular part;GO:0044424//intracellular part;GO:0044424//intracellular part GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0006916;GO:0048102//autophagic cell death;GO:0006916;GO:0048102//autophagic cell death;GO:0006916;GO:0048102//autophagic cell death 246471 1812.00 0.215 0.17 -0.338801913451759 Down 0.072150310394928 Ir56a ionotropic receptor 56a - - - - 34675 812.69 14.575 13.08 -0.156133342589776 Down 0.263010170387003 CG6153 CG6153, isoform C - - - GO:0033554//cellular response to stress;GO:0033554//cellular response to stress 38254 2488.00 1.39 1.535 0.143153772646672 Up 0.0911702549200898 Dbx Dbx K09339|1|1e-20|102|bta:519165|homeobox protein HLX1 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 40733 2280.34 57.33 51.38 -0.158083388797796 Down 0.341368379342227 CG2017 CG2017, isoform E - - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity - 35019 1681.00 0.675 0.755 0.161589142274248 Up 0.0746268656716418 CG13282 CG13282, isoform B K01046|1|3e-37|156|api:100163959|triacylglycerol lipase [EC:3.1.1.3] - GO:0003824//catalytic activity GO:0044238//primary metabolic process 318005 915.00 0.135 0.24 0.830074998557688 Up 0.102463346981905 sphinx1 sphinx1 K01310|1|8e-29|127|dme:Dmel_CG18179|chymotrypsin [EC:3.4.21.1];K01362|2|4e-20|98.6|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32429 16734.00 12.19 16.42 0.429756001157593 Up 0.495707304187029 hiw highwire, isoform B K10693|1|0.0|9254|dme:Dmel_CG32592|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] GO:0000152//nuclear ubiquitin ligase complex GO:0046914//transition metal ion binding GO:0007088//regulation of mitosis 42284 1168.00 36.015 41.495 0.204339603018606 Up 0.384097213049795 P5cr pyrroline 5-carboyxlate reductase K00286|1|3e-157|554|dme:Dmel_CG6009|pyrroline-5-carboxylate reductase [EC:1.5.1.2] - GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0006560//proline metabolic process 19835024 461.00 0.095 0.405 2.09192248944104 Up 0.214172500330207 42893 2887.00 48.36 50.85 0.072433529495739 Up 0.185741645753533 CG6356 CG6356 K08202|1|2e-45|184|dpo:Dpse_GA19517|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5;K08212|3|3e-43|177|gga:421757|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 16 GO:0031224//intrinsic to membrane - GO:0006810//transport 35878 1429.00 1.105 1.295 0.228905728295122 Up 0.110388323867389 ana2 anastral spindle 2, isoform B - GO:0005813//centrosome - GO:0051297//centrosome organization 19836200 1451.00 0.01 0.065 2.70043971814109 Up 0.09708096684718 37639 4682.00 3.09 2.615 -0.240795891657433 Down 0.176627922335227 MED23 mediator complex subunit 23 - GO:0043231//intracellular membrane-bounded organelle GO:0016251//general RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation 35485 1782.57 26.295 33.4 0.34505960588072 Up 0.511491216483952 d4 d4, isoform D K13196|1|4e-173|607|dme:Dmel_CG2682|zinc finger protein ubi-d4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development;GO:0010468//regulation of gene expression;GO:0048812//neuron projection morphogenesis;GO:0048513//organ development 37375 2547.00 15.065 17.495 0.215741991645386 Up 0.345099722625809 CG15651 CG15651 - - - - 3772126 192.00 3.61 4.995 0.468485840905247 Up 0.349887729494122 36716 1785.00 0.025 0.01 -1.32192809488736 Down 0.0577202483159424 Ir52d ionotropic receptor 52d - - - - 36304 7442.00 11.17 12.05 0.109403960634009 Up 0.186666226390173 Prp8 pre-mRNA processing factor 8 K12856|1|0.0|4597|dme:Dmel_CG8877|pre-mRNA-processing factor 8 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex - GO:0000377 39153 2807.48 161.58 166.8 0.0458706531091981 Up 0.156716417910448 CG43897 CG43897, isoform R - - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 5740775 1472.00 1.02 1.29 0.338801913451758 Up 0.145951657640999 CG34450 CG34450 - - GO:0046914//transition metal ion binding - 34594 5117.92 36.55 38.265 0.0661539934838289 Up 0.177618544445912 Pde1c Pde1c, isoform L K13755|1|0.0|1356|dme:Dmel_CG42325|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17] - GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004866//endopeptidase inhibitor activity GO:0009123;GO:0023060;GO:0006508//proteolysis;GO:0009123;GO:0023060;GO:0006508//proteolysis;GO:0009123;GO:0023060;GO:0006508//proteolysis;GO:0009123;GO:0023060;GO:0006508//proteolysis;GO:0009123;GO:0023060;GO:0006508//proteolysis;GO:0009123;GO:0023060;GO:0006508//proteolysis 40060 648.00 811.14 704.85 -0.202634671721481 Down 0.431382908466517 RpL26 ribosomal protein L26, isoform B K02898|1|2e-70|265|dya:Dyak_GE19574|large subunit ribosomal protein L26e GO:0033279 GO:0005198//structural molecule activity GO:0007052//mitotic spindle organization;GO:0010467//gene expression 32533 1182.72 12.105 15.34 0.341695403503997 Up 0.437954035134064 CG15602 CG15602, isoform B K01104|1|2e-06|53.5|gga:417015|protein-tyrosine phosphatase [EC:3.1.3.48];K12182|2|8e-06|51.6|cin:778843|hepatocyte growth factor-regulated tyrosine kinase substrate - GO:0046872//metal ion binding - 19835764 926.00 0.045 0.145 1.68805599368526 Up 0.1121384229296 19834990 2030.00 0.08 0.01 -3 Down 0.110718531237617 32858 2766.29 4.88 5.4 0.146078259487945 Up 0.167183991546691 Cyp18a1 cytochrome P450-18a1, isoform B K07422|1|7e-84|311|rno:310848|cytochrome P450, family 2, subfamily U;K07414|4|4e-79|296|xtr:548436|cytochrome P450, family 2, subfamily D [EC:1.14.14.1] GO:0044464//cell part;GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008202//steroid metabolic process;GO:0008202//steroid metabolic process 40248 3439.00 39.375 34.755 -0.180059378576026 Down 0.355138026680756 Ide insulin degrading metalloproteinase K01408|1|0.0|2055|dsi:Dsim_GD12197|insulysin [EC:3.4.24.56] - GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 37139 1165.89 57.04 49.055 -0.217573789117712 Down 0.418504821027605 CG5493 CG5493, isoform D K00456|1|2e-140|498|dme:Dmel_CG5493|cysteine dioxygenase [EC:1.13.11.20] - - - 42375 1565.00 0.085 0.125 0.556393348524385 Up 0.0683529256373002 CG4770 CG4770 K13356|1|2e-80|299|nvi:100117683|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 31082 3751.99 12.005 11.195 -0.100780875377819 Down 0.175439175802404 CG12773 CG12773, isoform C K10951|1|1e-55|219|tgu:100230871|solute carrier family 12 member 2 - - - 32851 1249.00 6.65 6.425 -0.0496578863073114 Down 0.0863162065777308 CG6540 CG6540 - - - - 42753 2615.00 4.295 4.09 -0.0705572881967148 Down 0.0899484876502444 cdc16 cell division cycle 16 ortholog K03353|1|0.0|1356|dme:Dmel_CG6759|anaphase-promoting complex subunit 6 GO:0000152//nuclear ubiquitin ligase complex - GO:0007088//regulation of mitosis 19835697 928.00 0.13 0.21 0.691877704637668 Up 0.0911042134460441 39758 2521.00 0.455 0.55 0.273565073325964 Up 0.0870426627922335 CG5235 CG5235, isoform B K00503|1|2e-69|264|dpo:Dpse_GA11749|dopamine beta-monooxygenase [EC:1.14.17.1] - GO:0046914//transition metal ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0006576//cellular biogenic amine metabolic process;GO:0006547//histidine metabolic process 40763 1360.00 4.22 4.575 0.11652874446422 Up 0.132016906617356 Osi9 osiris 9 K01759|1|3e-06|53.1|aag:AaeL_AAEL002957|lactoylglutathione lyase [EC:4.4.1.5] - - - 317977 2591.00 0.05 0.035 -0.514573172829758 Down 0.0473847576277902 CG32320 CG32320 - - - - 7354465 10901.00 3.325 4.05 0.284567567383435 Up 0.229626205256901 CG42232 CG42232 K04574|1|7e-27|125|ssc:100156492|neurofilament heavy polypeptide - - - 38791 1022.00 0.045 0.045 0 - 0.0382380134724607 CG14826 CG14826, isoform C - - - - 19835944 342.00 0.01 0.15 3.90689059560852 Up 0.171410645885616 36536 1051.56 133.965 119.37 -0.166415823265455 Down 0.376238277638357 CG6543 CG6543, isoform B K07511|1|3e-165|581|dme:Dmel_CG6543|enoyl-CoA hydratase [EC:4.2.1.17] GO:0031980;GO:0015630//microtubule cytoskeleton;GO:0031980;GO:0015630//microtubule cytoskeleton GO:0016836//hydro-lyase activity;GO:0016836//hydro-lyase activity GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process 32121 642.98 69.135 17 -2.02388152203274 Down 0.777539294677057 CG2444 CG2444, isoform B - - - - 43657 1378.00 736.185 296.44 -1.31232822446343 Down 0.76135913353586 Cpr100A cuticular protein 100A - - - - 59215 3691.64 16.105 17.38 0.109919421431585 Up 0.212125214634791 CG32164 CG32164, isoform B - - GO:0022892 GO:0015031//protein transport 19835791 353.00 0.125 0.3 1.26303440583379 Up 0.147107383436798 3885648 570.00 0.01 0.085 3.08746284125034 Up 0.117619865275393 CG34028 CG34028 - - - - 32865 987.44 58.07 30.945 -0.908086712095048 Down 0.699214106458856 CG6891 CG6891, isoform C - GO:0044464//cell part;GO:0044464//cell part GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding - 41734 1006.00 0.195 0.56 1.52195270319536 Up 0.224607053229428 CG14840 CG14840 - - - - 35242 1197.81 12.12 10.88 -0.155711142222612 Down 0.247490423986263 CG10165 CG10165, isoform E K08371|1|3e-94|345|dpo:Dpse_GA10125|cytochrome b-561 domain containing 2 - GO:0008144//drug binding;GO:0016597//amino acid binding;GO:0008144//drug binding;GO:0016597//amino acid binding - 43576 1897.08 18.465 17 -0.11925851618055 Down 0.229527143045833 CG7946 CG7946, isoform B K00020|1|1e-10|68.6|mcc:706933|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] - - - 35123 2880.91 27.94 15.855 -0.817394143305624 Down 0.654173821159688 CG10383 CG10383, isoform B - GO:0005789//endoplasmic reticulum membrane GO:0016787//hydrolase activity GO:0030384 19835409 1062.00 120.13 95.39 -0.332686541969168 Down 0.546988508783516 19835263 772.00 0.01 0.175 4.12928301694497 Up 0.187062475234447 - CG44954 - - - - 34134 1335.00 19.015 19.165 0.0113360591699265 Up 0.0581825386342623 wol wollknaeuel K00729|1|2e-170|598|dme:Dmel_CG7870|dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117] - GO:0016740//transferase activity GO:0009790//embryo development;GO:0007389//pattern specification process 19836206 3451.00 0.245 0.015 -4.02974734339405 Down 0.218498216880201 36176 2664.85 50.89 57.635 0.179562991732418 Up 0.36989829612997 metro menage a trois, isoform D K06091|1|7e-106|385|bfo:BRAFLDRAFT_60486|membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) - GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding - 14462599 905.00 0.01 0.055 2.4594316186373 Up 0.0799432043323207 246461 609.00 17.14 16.53 -0.0522803848201861 Down 0.122539955091798 CG30109 CG30109 - - - - 14462764 617.00 0.375 0.295 -0.34617564113404 Down 0.0858539162594109 40896 2121.30 16.74 13.59 -0.300754071782953 Down 0.417613261127988 alpha-Est10 alpha-Esterase-10, isoform D K01044|1|0.0|1177|dme:Dmel_CG1131|carboxylesterase [EC:3.1.1.1];K01050|1|0.0|1177|dme:Dmel_CG1131|cholinesterase [EC:3.1.1.8];K01066|3|2e-154|546|dpo:Dpse_GA10843|esterase / lipase [EC:3.1.1.-] - GO:0004091//carboxylesterase activity - 31520 2544.78 108.705 83.925 -0.373245763120985 Down 0.571291771232334 CG16721 CG16721, isoform C - - - - 41086 2221.00 14.65 13.46 -0.122222254699293 Down 0.21582353718135 hyx hyrax, isoform B - GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0005515//protein binding;GO:0005515//protein binding GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048592//eye morphogenesis;GO:0008589//regulation of smoothened signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048592//eye morphogenesis;GO:0008589//regulation of smoothened signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process 8674052 1126.00 0.485 0.535 0.141554144214019 Up 0.063102628450667 CG42633 CG42633 - GO:0043231//intracellular membrane-bounded organelle;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression 34333 1941.88 128.94 120.595 -0.0965297958286703 Down 0.255844670453044 Trp1 translocation protein 1, isoform D K12275|1|3e-139|495|dme:Dmel_CG4758|translocation protein SEC62 GO:0044425//membrane part;GO:0044425//membrane part - - 31989 2782.00 6.93 5.66 -0.292053299305331 Down 0.302370888918241 CG2124 CG2124 K03454|1|2e-11|72.0|tad:TRIADDRAFT_25969|mitochondrial carrier protein, MC family - - - 37696 818.00 0.195 0.17 -0.197939377611909 Down 0.0565645225201427 CG30409 CG30409, isoform B - - - - 43758 11118.14 15.4 20.7 0.426700416804424 Up 0.519052965262185 RhoGAP100F Rho GTPase activating protein at 100F, isoform J K08878|1|6e-29|131|xtr:100170543|breakpoint cluster region protein [EC:2.7.11.1] GO:0044464//cell part;GO:0044464//cell part;GO:0044464//cell part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0023060;GO:0023060;GO:0023060 35948 1667.00 9.325 6.405 -0.541905154800953 Down 0.474144762911108 Cyp4p3 Cyp4p3 K00517|1|0.0|1008|dme:Dmel_CG10843| [EC:1.14.-.-] GO:0044464//cell part GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process 35507 1661.00 34.395 32.72 -0.0720261073602008 Down 0.176594901598204 CG17337 CG17337, isoform C K08660|1|0.0|979|dme:Dmel_CG17337|cytosolic nonspecific dipeptidase - GO:0005488//binding;GO:0008238//exopeptidase activity GO:0007154//cell communication;GO:0019538//protein metabolic process 39039 1526.00 0.47 0.465 -0.0154300405696059 Down 0.0413749834896315 Doc1 Dorsocross1, isoform B K10180|1|4e-166|584|dpo:Dpse_GA18682|T-box protein 6;K10177|3|3e-69|262|xtr:613116|T-box protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009792//embryo development ending in birth or egg hatching;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent;GO:0007507//heart development 43668 1031.00 0.04 0.09 1.16992500144231 Up 0.0797781006472064 Ctr1C copper transporter 1C - GO:0031224//intrinsic to membrane GO:0015082 GO:0000041//transition metal ion transport 40933 3243.40 32.27 33.915 0.0717299149857434 Up 0.176132611279884 CG2943 CG2943, isoform D - - - - 317997 410.00 30.16 4.43 -2.76725782471365 Down 0.78348302734117 CG32368 CG32368 - - - - 31935 7821.66 10.81 5.685 -0.927134268842402 Down 0.594142121252146 Cht6 Cht6, isoform K K01183|1|0.0|1469|dme:Dmel_CG2989|chitinase [EC:3.2.1.14] - GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0030247//polysaccharide binding;GO:0043167//ion binding GO:0006026;GO:0006026 35859 588.00 13.025 2.04 -2.67464231519438 Down 0.740060758156122 PGRP-SC1a PGRP-SC1a K01446|1|1e-105|381|dme:Dmel_CG8577|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0016021//integral to membrane GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding GO:0000270//peptidoglycan metabolic process;GO:0006952//defense response;GO:0009581//detection of external stimulus 32885 2713.72 28.435 29.64 0.0598776433536018 Up 0.155560692114648 CG7332 CG7332, isoform B - - GO:0046872//metal ion binding - 35378 5240.83 42.475 48.285 0.184961130127251 Up 0.364548936732268 Dap160 dynamin associated protein 160, isoform H K12472|1|4e-22|107|dre:795505|epidermal growth factor receptor substrate 15;K07365|4|7e-21|103|dre:445098|NCK adaptor protein;K13738|5|7e-21|103|rno:316258|CD2-associated protein GO:0044448//cell cortex part;GO:0016020//membrane;GO:0044448//cell cortex part;GO:0016020//membrane;GO:0044448//cell cortex part;GO:0016020//membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0007416//synapse assembly;GO:0008593//regulation of Notch signaling pathway;GO:0007405//neuroblast proliferation;GO:0033674//positive regulation of kinase activity;GO:0033036;GO:0006897//endocytosis;GO:0007416//synapse assembly;GO:0008593//regulation of Notch signaling pathway;GO:0007405//neuroblast proliferation;GO:0033674//positive regulation of kinase activity;GO:0033036;GO:0006897//endocytosis;GO:0007416//synapse assembly;GO:0008593//regulation of Notch signaling pathway;GO:0007405//neuroblast proliferation;GO:0033674//positive regulation of kinase activity;GO:0033036;GO:0006897//endocytosis 12798230 451.00 1.245 1.22 -0.0292645945051949 Down 0.0473517368907674 CG43131 CG43131 - - - - 38066 761.00 1.14 1.155 0.0188590272513158 Up 0.0413749834896315 CG13891 CG13891 - - - - 32513 780.35 72.97 83.38 0.19239791838638 Up 0.395654471007793 l(1)G0136 lethal (1) G0136, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0051540 GO:0031163;GO:0006779//porphyrin-containing compound biosynthetic process 40894 911.00 16.52 18.545 0.166816581083565 Up 0.295007264562145 CG1142 CG1142 K11135|1|4e-06|52.0|cqu:CpipJ_CPIJ017220|Pin2-interacting protein X1 - - - 36753 4646.00 58.32 70.845 0.280675316544784 Up 0.488739928675208 Strn-Mlck Stretchin-Mlck, isoform V K12567|1|9e-48|195|mmu:22138|titin [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005198//structural molecule activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005198//structural molecule activity;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005198//structural molecule activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0005198//structural molecule activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004674//protein serine/threonine kinase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process 38224 2546.02 15.955 16.08 0.0112587978996166 Up 0.0563994188350284 CG8001 CG8001, isoform D K11804|1|0.0|1397|dme:Dmel_CG8001|WD repeat-containing protein 42A - - - 34830 4314.00 0.08 0.035 -1.1926450779424 Down 0.0725795799762251 CG43333 CG43333 - - - - 39547 1872.00 84.04 66.855 -0.330040700339235 Down 0.538766345264826 26-29-p 26-29kD-proteinase K01365|1|2e-66|253|nve:NEMVE_v1g181181|cathepsin L [EC:3.4.22.15] GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 35169 2317.00 52.835 57.185 0.114142823572149 Up 0.262679963016775 hk hook K10352|1|7e-16|86.3|phu:Phum_PHUM344210|myosin heavy chain GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0005887//integral to plasma membrane GO:0015631//tubulin binding;GO:0003824//catalytic activity;GO:0005267//potassium channel activity GO:0006909//phagocytosis;GO:0042051//compound eye photoreceptor development;GO:0007010//cytoskeleton organization;GO:0010259//multicellular organismal aging;GO:0022410;GO:0046907//intracellular transport;GO:0008152//metabolic process;GO:0030001//metal ion transport 32789 1039.02 164.205 116.38 -0.496654906275471 Down 0.63739928675208 scu scully, isoform B K08683|1|9e-139|493|dme:Dmel_CG7113|3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0032787//monocarboxylic acid metabolic process;GO:0016125//sterol metabolic process;GO:0006732//coenzyme metabolic process 40871 889.89 6.435 4.6 -0.484306287276327 Down 0.394597807423062 CG10053 CG10053, isoform B - GO:0044464//cell part GO:0005488//binding - 42952 2804.00 2.28 3.28 0.524661990453342 Up 0.305639941883503 Ets96B Ets96B, isoform C K09431|1|7e-50|199|tca:660644|ETS translocation variant 1/4/5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 39067 891.00 13.105 11.92 -0.136733117866256 Down 0.231178179896975 CG4447 CG4447 K02838|1|4e-116|417|dme:Dmel_CG4447|ribosome recycling factor GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression 4379908 1730.00 19.49 22.905 0.232928472260118 Up 0.379540351340642 CG34140 CG34140 K01090|1|2e-109|396|dme:Dmel_CG34099|protein phosphatase [EC:3.1.3.16];K01104|2|1e-24|114|cfa:488433|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0016866//intramolecular transferase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process;GO:0006464//cellular protein modification process;GO:0001522//pseudouridine synthesis;GO:0006796//phosphate-containing compound metabolic process 12798363 535.00 1.43 0.465 -1.62071252567036 Down 0.36666226390173 CG43293 CG43293, isoform B - - - - 40980 1220.00 19.015 24.68 0.376204455518827 Up 0.508354246466781 mRpL1 mitochondrial ribosomal protein L1 - GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0009987//cellular process;GO:0040007//growth;GO:0007275//multicellular organismal development;GO:0010467//gene expression 35310 1539.00 9.605 8.88 -0.113225937315421 Down 0.175009906221107 CG10949 CG10949, isoform B K09427|1|2e-10|67.4|dpo:Dpse_GA13983|Adh transcription factor 1 - GO:0003676//nucleic acid binding - 35711 558.00 30.785 35.135 0.190681330008753 Up 0.362963941355171 mRpL52 mitochondrial ribosomal protein L52 - GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression 33935 1467.81 117.295 69.28 -0.759630680926156 Down 0.695020472856954 Galt Galactose-1-phosphate uridylyltransferase, isoform B K00965|1|0.0|710|dme:Dmel_CG9232|UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] - GO:0046914//transition metal ion binding;GO:0070569//uridylyltransferase activity GO:0019318//hexose metabolic process 42335 2142.68 4.39 3.1 -0.501952724261121 Down 0.343613789459781 CG7342 CG7342, isoform B K08202|1|5e-47|189|bfo:BRAFLDRAFT_233027|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 5 GO:0031224//intrinsic to membrane - GO:0006810//transport 5740551 543.00 0.235 0.94 2 Up 0.326608109893013 CG34260 CG34260 - - - - 43460 2792.00 4.325 4.385 0.0198767099206461 Up 0.0528001584995377 Brd8 Brd8 K11321|1|0.0|1245|dme:Dmel_CG14514|bromodomain-containing protein 8 - - - 31794 1117.00 3.45 4.61 0.418170388763806 Up 0.316338660678906 CG12112 CG12112, isoform B - - - - 2768961 3790.00 10.04 9.805 -0.034169733758623 Down 0.0789195614846123 CG7369 CG7369 K07376|1|2e-84|314|mcc:696308|protein kinase, cGMP-dependent [EC:2.7.11.12];K08018|3|8e-21|103|xtr:100145659|Rap guanine nucleotide exchange factor (GEF) 2 GO:0044464//cell part GO:0030695//GTPase regulator activity GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction 36872 485.29 34.96 39.48 0.175416804955799 Up 0.354081363096024 Acp53C14a accessory gland protein 53C14a, isoform B - - - - 246522 4010.00 0.22 0.355 0.690315500867385 Up 0.111940298507463 CG30275 CG30275, isoform N - - - - 19835563 3439.00 15.6 16.275 0.0611115143033869 Up 0.135352001056664 - CG45088 - - - - 318600 2895.00 5.795 4.915 -0.237617244665891 Down 0.240622110685511 Wsck wsck K05120|1|6e-22|106|dre:30746|tyrosine kinase receptor 1 [EC:2.7.10.1];K05102|4|1e-19|99.0|rno:312279|Eph receptor A1 [EC:2.7.10.1];K04362|5|4e-19|97.4|spu:373310|fibroblast growth factor receptor 1 [EC:2.7.10.1] GO:0016020//membrane GO:0004871//signal transducer activity;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process 32580 1096.00 0.805 0.565 -0.510737915699429 Down 0.145522388059701 CG12507 CG12507 - - - - 7354457 1339.00 0.065 0.035 -0.893084796083488 Down 0.0629375247655528 38723 11690.00 5.28 5.5 0.0588936890535686 Up 0.0892220314357416 LanA laminin A K06242|1|0.0|1919|cin:100176802|laminin, alpha 5 GO:0043256//laminin complex GO:0005515//protein binding GO:2000026//regulation of multicellular organismal development;GO:0016477//cell migration;GO:0007155//cell adhesion 37239 2585.00 2.465 2.125 -0.214124805352847 Down 0.145456346585656 CG7744 CG7744 - - - - 37815 1842.00 54.315 68.61 0.337068188935495 Up 0.539657905164443 Alas aminolevulinate synthase K00643|1|0.0|1041|dme:Dmel_CG3017|5-aminolevulinate synthase [EC:2.3.1.37] GO:0031980 GO:0016749;GO:0048037//cofactor binding GO:0006779//porphyrin-containing compound biosynthetic process 41995 4983.00 12.66 12.215 -0.0516235411610851 Down 0.112567692510897 Pak3 Pak3, isoform D K08286|1|0.0|994|dme:Dmel_CG14895|protein-serine/threonine kinase [EC:2.7.11.-];K04409|4|7e-139|495|cqu:CpipJ_CPIJ006042|p21-activated kinase 1 [EC:2.7.11.1] - - - 35933 1267.00 92.765 85.79 -0.112771091171173 Down 0.27096816800951 shrb shrub K12194|1|2e-64|246|dme:Dmel_CG8055|charged multivesicular body protein 4 - - - 35154 4771.43 33.57 32.28 -0.0565319584197697 Down 0.157640998547088 Nak Numb-associated kinase, isoform E K08853|1|6e-111|402|xtr:100135375|AP2-associated kinase [EC:2.7.11.1];K08854|2|5e-110|399|gga:422578|BMP2 inducible kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032559;GO:0005488//binding;GO:0004672//protein kinase activity;GO:0004672//protein kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0051301//cell division;GO:0006464//cellular protein modification process;GO:0051301//cell division;GO:0006464//cellular protein modification process;GO:0051301//cell division 3885646 7385.44 26.06 16.3 -0.676965119449695 Down 0.622837141725003 CG33978 CG33978, isoform G K02599|1|9e-07|58.5|bfo:BRAFLDRAFT_99311|Notch - - - 41869 1700.84 44.58 40.14 -0.151355999897135 Down 0.319607713644169 CG5044 CG5044, isoform B K05605|1|0.0|722|dme:Dmel_CG5044|3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4] - - - 33692 3856.67 15.56 13.78 -0.1752661722819 Down 0.291341962752609 Cf2 chorion factor 2, isoform F K02215|1|0.0|803|dme:Dmel_CG11924|chorion factor 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent;GO:0007525//somatic muscle development;GO:0006351//transcription, DNA-dependent;GO:0007525//somatic muscle development;GO:0006351//transcription, DNA-dependent;GO:0007525//somatic muscle development 35888 1371.35 20.465 25.625 0.324393337837086 Up 0.473253203011491 CG8248 CG8248, isoform B - - - - 33353 914.96 9.29 8.82 -0.0748999408251321 Down 0.126205256901334 CG17652 CG17652, isoform B K07158|1|3e-104|377|dpo:Dpse_GA14597| - - - 33118 1982.83 56.655 63.87 0.172935166012121 Up 0.360454365341434 Hlc helicase, isoform B K01509|1|0.0|807|dpo:Dpse_GA14086|adenosinetriphosphatase [EC:3.6.1.3];K01529|2|2e-133|476|bta:508728| [EC:3.6.1.-] - GO:0032559;GO:0042623//ATPase activity, coupled - 19835071 721.00 0.06 0.01 -2.58496250072116 Down 0.0905758816536785 41020 3830.71 25.15 27.855 0.147377915963688 Up 0.298111213842293 Mkk4 MAP kinase kinase 4, isoform C K04430|1|0.0|751|dme:Dmel_CG9738|mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] GO:0043005//neuron projection;GO:0043005//neuron projection GO:0004708//MAP kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559;GO:0004708//MAP kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0048468//cell development;GO:0000187//activation of MAPK activity;GO:0048468//cell development;GO:0000187//activation of MAPK activity 14462775 521.00 0.475 0.53 0.158064846232252 Up 0.0673292827895919 CG43923 CG43923 - - - - 38679 1361.00 0.28 0.38 0.440572591385981 Up 0.0952978470479461 CG10477 CG10477 K01310|1|5e-75|280|dpo:Dpse_GA19618|chymotrypsin [EC:3.4.21.1];K01362|3|3e-64|244|dpo:Dpse_GA15953| [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32029 878.00 0.05 0.105 1.0703893278914 Up 0.0856557918372738 Rab9Fb Rab at 9Fb K07976|1|4e-113|407|dme:Dmel_CG32670|Rab family, other - GO:0032561//guanyl ribonucleotide binding GO:0006810//transport;GO:0035556//intracellular signal transduction 34442 2666.00 13.19 12.515 -0.0757862735632129 Down 0.151598203671906 CG7456 CG7456 - GO:0044424//intracellular part - GO:0022406//membrane docking;GO:0016192//vesicle-mediated transport 37720 870.00 2.195 2.105 -0.0604007064689624 Down 0.0647536653018095 CG13559 CG13559 - - - - 34398 2086.00 5.505 7.775 0.498100111453596 Up 0.429830933826443 CG5022 CG5022 K06107|1|7e-51|202|mmu:13821|erythrocyte membrane protein band 4.1 GO:0044425//membrane part;GO:0043232 GO:0005515//protein binding - 34384 986.00 38.96 30.58 -0.349405270721538 Down 0.521331396116761 CG4968 CG4968 K09602|1|8e-152|536|dme:Dmel_CG4968|ubiquitin thioesterase protein OTUB1 [EC:3.4.-.-] - - - 40687 722.16 772.42 777.35 0.0091787949738948 Up 0.070829480914014 RpL13A ribosomal protein L13A, isoform C K02872|1|1e-114|412|dya:Dyak_GE10144|large subunit ribosomal protein L13Ae GO:0033279 GO:0005198//structural molecule activity GO:0009887//organ morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0010467//gene expression 10178865 693.00 0.175 0.45 1.36257007938471 Up 0.18963809272223 32422 1979.00 0.04 0.045 0.169925001442312 Up 0.0382380134724607 CG12398 CG12398 K00115|1|0.0|1285|dme:Dmel_CG12398|glucose dehydrogenase (acceptor) [EC:1.1.99.10];K00108|2|1e-139|496|dme:Dmel_CG9518|choline dehydrogenase [EC:1.1.99.1] GO:0030312//external encapsulating structure GO:0030554//adenyl nucleotide binding;GO:0016491//oxidoreductase activity GO:0044281//small molecule metabolic process 34569 6115.68 2.01 2.44 0.279685646383958 Up 0.176099590542861 salm spalt major, isoform B K09231|1|1e-16|90.1|tca:641605|krueppel-like family, other;K09228|4|9e-16|87.4|rno:690419|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046872//metal ion binding - 39770 4109.47 1.81 1.37 -0.401813804122678 Down 0.193732664113063 CG16838 CG16838, isoform E K04574|1|9e-09|63.5|mcc:717705|neurofilament heavy polypeptide - GO:0000166//nucleotide binding;GO:0000166//nucleotide binding - 33498 4040.75 197.78 259.405 0.391309743027736 Up 0.594043059041078 Rbp9 RNA-binding protein 9, isoform K K13208|1|0.0|657|dan:Dana_GF14992|ELAV like protein 2/3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0003006//developmental process involved in reproduction;GO:0003006//developmental process involved in reproduction;GO:0003006//developmental process involved in reproduction;GO:0003006//developmental process involved in reproduction;GO:0003006//developmental process involved in reproduction;GO:0003006//developmental process involved in reproduction;GO:0003006//developmental process involved in reproduction 34582 6939.00 11.005 14.23 0.370776516634925 Up 0.448355567296262 kek2 kekkon-2 K07523|1|3e-63|244|dme:Dmel_CG4192|netrin-G1 ligand;K06850|2|2e-23|112|dre:80354|slit 3 - GO:0005488//binding - 33004 611.00 29.445 22.705 -0.375012636762993 Down 0.521925769383173 CG12655 CG12655 - - - - 38878 1020.00 1.815 3.085 0.765300941153667 Up 0.369006736230353 eIF4E-5 eIF4E-5 K03259|1|3e-113|408|dse:Dsec_GM25004|translation initiation factor eIF-4E GO:0043234//protein complex;GO:0044424//intracellular part GO:0008135//translation factor activity, nucleic acid binding GO:0048102//autophagic cell death;GO:0006412//translation 43402 2785.00 21.18 22.99 0.118303876725844 Up 0.242636375643904 WASp WASp, isoform D K05747|1|3e-159|562|dme:Dmel_CG1520|Wiskott-Aldrich syndrome protein GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005856//cytoskeleton;GO:0042995//cell projection GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding GO:0008544//epidermis development;GO:0008360//regulation of cell shape;GO:0045010//actin nucleation;GO:0007409//axonogenesis;GO:0003382//epithelial cell morphogenesis;GO:0051301//cell division;GO:0000768//syncytium formation by plasma membrane fusion;GO:0003002//regionalization;GO:0009887//organ morphogenesis;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0008544//epidermis development;GO:0008360//regulation of cell shape;GO:0045010//actin nucleation;GO:0007409//axonogenesis;GO:0003382//epithelial cell morphogenesis;GO:0051301//cell division;GO:0000768//syncytium formation by plasma membrane fusion;GO:0003002//regionalization;GO:0009887//organ morphogenesis;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0008544//epidermis development;GO:0008360//regulation of cell shape;GO:0045010//actin nucleation;GO:0007409//axonogenesis;GO:0003382//epithelial cell morphogenesis;GO:0051301//cell division;GO:0000768//syncytium formation by plasma membrane fusion;GO:0003002//regionalization;GO:0009887//organ morphogenesis;GO:0008582//regulation of synaptic growth at neuromuscular junction 40376 986.00 2.21 2.6 0.234465253637023 Up 0.159259014661207 CG7202 CG7202 - - - - 43770 5219.72 95.675 107.87 0.173079788016531 Up 0.373233390569278 Ank ankyrin, isoform E K10380|1|0.0|3029|dme:Dmel_CG1651|ankyrin GO:0043232;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0007010//cytoskeleton organization;GO:0023060 35203 2809.00 0.125 0.27 1.11103131238874 Up 0.13102628450667 CG31797 CG31797 - - - - 261623 1918.19 1.115 21.07 4.240074698897 Up 0.827796856425835 CG31683 CG31683, isoform B K06129|1|0.0|842|dme:Dmel_CG31683|lysophospholipase III [EC:3.1.1.5];K00650|2|0.0|839|dme:Dmel_CG18858|lecithin-cholesterol acyltransferase [EC:2.3.1.43];K00680|2|0.0|839|dme:Dmel_CG18858| [EC:2.3.1.-] - GO:0008374//O-acyltransferase activity GO:0044238//primary metabolic process 40261 1029.00 15.405 16.55 0.103432534655229 Up 0.195647866860388 mRpL15 mitochondrial ribosomal protein L15 - GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 37523 1594.00 1.52 2.555 0.749251967494036 Up 0.334367983093383 mei-S332 meiotic from via salaria 332, isoform B - GO:0044427//chromosomal part;GO:0043231//intracellular membrane-bounded organelle - GO:0007127//meiosis I;GO:0007059//chromosome segregation 38801 7736.21 8.04 10.31 0.35877692618918 Up 0.400871747457403 unc-13-4A unc-13-4A, isoform C K02677|1|8e-10|67.4|nve:NEMVE_v1g93932|classical protein kinase C [EC:2.7.11.13] - - - 12798040 140.00 0.01 0.47 5.55458885167764 Up 0.34823669264298 31349 3369.35 97.135 110 0.179440392733323 Up 0.386903975696738 Vap-33-1 VAMP-associated protein of 33kDa ortholog A, isoform E K10707|1|8e-34|145|dre:323628|vesicle-associated membrane protein-associated protein B;K06096|3|2e-33|144|mdo:100013337|vesicle-associated membrane protein-associated protein A GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - GO:0016079//synaptic vesicle exocytosis;GO:0048741//skeletal muscle fiber development;GO:0006915//apoptotic process;GO:0016079//synaptic vesicle exocytosis;GO:0048741//skeletal muscle fiber development;GO:0006915//apoptotic process;GO:0016079//synaptic vesicle exocytosis;GO:0048741//skeletal muscle fiber development;GO:0006915//apoptotic process;GO:0016079//synaptic vesicle exocytosis;GO:0048741//skeletal muscle fiber development;GO:0006915//apoptotic process 50198 406.00 1.14 0.24 -2.24792751344359 Down 0.370624752344472 CG13946 CG13946 - - - - 39402 1561.90 10.105 12.455 0.301655699861101 Up 0.384790648527275 Pbgs porphobilinogen synthase, isoform B K01698|1|0.0|658|dme:Dmel_CG10335|porphobilinogen synthase [EC:4.2.1.24] - GO:0043169//cation binding;GO:0016836//hydro-lyase activity GO:0006778//porphyrin-containing compound metabolic process;GO:0018130 34901 1560.00 0.1 0.275 1.4594316186373 Up 0.149583938713512 CG15262 CG15262 K12605|1|3e-20|100|dgr:Dgri_GH17541|CCR4-NOT transcription complex subunit 2 GO:0043231//intracellular membrane-bounded organelle - GO:0010468//regulation of gene expression 34038 3377.24 113.71 127.8 0.168528701526905 Up 0.375742966583014 Slob slowpoke binding protein, isoform K K11322|1|4e-17|90.5|tca:660832|enhancer of polycomb-like protein - GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity;GO:0005488//binding;GO:0016301//kinase activity GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis;GO:0051969;GO:0006950//response to stress;GO:0006873//cellular ion homeostasis 36001 2530.00 4.81 4.08 -0.237467741798546 Down 0.220776647734777 dap dacapo - GO:0043231//intracellular membrane-bounded organelle GO:0016538//cyclin-dependent protein kinase regulator activity GO:0006470//protein dephosphorylation;GO:0060541//respiratory system development;GO:0043549//regulation of kinase activity;GO:0007292//female gamete generation;GO:0007090//regulation of S phase of mitotic cell cycle;GO:0008356//asymmetric cell division;GO:0003006//developmental process involved in reproduction;GO:0007560//imaginal disc morphogenesis 33778 4023.92 3.855 5.045 0.388123409191323 Up 0.316272619204861 Cap-D3 chromosome associated protein D3, isoform B K11491|1|0.0|2405|dme:Dmel_CG31989|condensin-2 complex subunit D3 GO:0000793//condensed chromosome;GO:0000793//condensed chromosome GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0051322//anaphase;GO:0007140//male meiosis;GO:0006041//glucosamine metabolic process;GO:0007135//meiosis II;GO:0006996//organelle organization;GO:0051322//anaphase;GO:0007140//male meiosis;GO:0006041//glucosamine metabolic process;GO:0007135//meiosis II;GO:0006996//organelle organization 37881 2151.00 0.07 0.19 1.44057259138598 Up 0.120888918240655 Ir60a ionotropic receptor 60a K09884|1|4e-27|123|tca:663053|aquaporin rerated protein, invertebrate;K00683|2|1e-05|52.4|tca:659407|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] - - - 53426 3448.00 0.01 0.075 2.90689059560852 Up 0.107449478272355 ACXE ACXE K03458|1|0.0|2169|dme:Dmel_CG17178|nucleobase:cation symporter-2, NCS2 family - GO:0016829//lyase activity GO:0009124//nucleoside monophosphate biosynthetic process;GO:0048232//male gamete generation 40268 1314.00 39.815 42.87 0.106656359535006 Up 0.253467177387399 CG5955 CG5955 K00060|1|4e-115|414|bfo:BRAFLDRAFT_116658|threonine 3-dehydrogenase [EC:1.1.1.103] - GO:0048037//cofactor binding GO:0008152//metabolic process 45396 2122.00 2.395 1.495 -0.679880171538075 Down 0.304550257561749 E5 E5, isoform B K09317|1|2e-58|227|dme:Dmel_CG9930|homeobox protein EMX GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-dependent 31055 1107.00 156.545 158.065 0.013940520166214 Up 0.0696737551182142 CG14629 CG14629 - - - - 33951 2967.17 35.585 50.59 0.507583003177466 Up 0.611610091137234 CG17378 CG17378, isoform C - - - - 246439 675.00 25.955 26.05 0.00527088477404212 Up 0.0547483819838859 blos1 biogenesis of lysosome-related organelles complex 1, subunit 1 - - - - 19834730 1401.00 0.03 0.01 -1.58496250072116 Down 0.0591731607449478 37687 3915.00 0.015 0.045 1.58496250072116 Up 0.0670320961563862 ord orientation disruptor, isoform B - GO:0043073//germ cell nucleus;GO:0043234//protein complex GO:0005488//binding GO:0007062//sister chromatid cohesion;GO:0007140//male meiosis;GO:0007143//female meiosis;GO:0019953//sexual reproduction;GO:0000087//M phase of mitotic cell cycle 19835035 508.00 6.21 4.965 -0.322799550692108 Down 0.310196803592656 31340 2702.20 9.865 14.855 0.590557649111856 Up 0.550686831330075 yin yin, isoform D K03305|1|4e-139|495|tca:661253|proton-dependent oligopeptide transporter, POT family GO:0016021//integral to membrane;GO:0016021//integral to membrane;GO:0016021//integral to membrane GO:0015322;GO:0015322;GO:0015322 GO:0015833//peptide transport;GO:0015833//peptide transport;GO:0015833//peptide transport 14462568 996.00 0.09 0.135 0.584962500721156 Up 0.0687491744815744 41635 2966.00 0.84 1.175 0.484199523786239 Up 0.171905956940959 CG8774 CG8774, isoform B K11141|1|0.0|1788|dme:Dmel_CG8774|glutamyl aminopeptidase [EC:3.4.11.7] - - - 5740400 625.00 0.07 0.075 0.0995356735509144 Up 0.0433232069739797 CG34169 CG34169 - - - - 33239 1880.00 17.45 25.39 0.541033358550491 Up 0.58364152687888 Pph13 PvuII-PstI homology 13 K09452|1|1e-27|125|dre:30657|homeobox protein aristaless-related GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0010468//regulation of gene expression;GO:0042051//compound eye photoreceptor development;GO:0006351//transcription, DNA-dependent 33104 5303.00 0.945 0.82 -0.204690419602989 Down 0.0884955752212389 CG1801 CG1801 K05643|1|4e-86|320|gga:416386|ATP-binding cassette, subfamily A (ABC1), member 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032559 - 3772004 1023.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 His1:CG33843 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 41199 2652.00 0.86 1.31 0.607158246835352 Up 0.209648659358077 topi matotopetli K09228|1|7e-38|159|api:100159445|KRAB domain-containing zinc finger protein GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0007126//meiosis;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-dependent 35954 2439.00 9.415 10.985 0.222501869809048 Up 0.299795271430458 Mad1 Mad1 K06638|1|0.0|1238|dme:Dmel_CG2072|mitotic spindle assembly checkpoint protein MAD1 - - - 42212 3341.00 0.02 0.015 -0.415037499278844 Down 0.0473847576277902 CG14309 CG14309 - GO:0016469//proton-transporting two-sector ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process 5740107 151.00 0.01 0.495 5.62935662007961 Up 0.356888125742967 36964 4009.99 23.74 26.935 0.182162130197189 Up 0.335820895522388 CG14478 CG14478, isoform D - - - - 31381 4726.78 12.155 13.02 0.0991795551369068 Up 0.179401664245146 rb ruby, isoform D K12397|1|0.0|1907|dme:Dmel_CG11427|AP-3 complex subunit beta GO:0043234//protein complex;GO:0030136//clathrin-coated vesicle GO:0005488//binding;GO:0022892 GO:0042441//eye pigment metabolic process;GO:0006901//vesicle coating;GO:0010259//multicellular organismal aging;GO:0048753//pigment granule organization;GO:0016567//protein ubiquitination;GO:0007033//vacuole organization;GO:0015031//protein transport 31332 2212.05 27.245 21.87 -0.317038270528434 Down 0.476489235239731 Rala Ras-like protein A, isoform C K07834|1|3e-127|403|dya:Dyak_GE16885|Ras-related protein Ral-A GO:0016020//membrane;GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0032155;GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0032155 GO:0017111//nucleoside-triphosphatase activity;GO:0004620//phospholipase activity;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0031753;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0031753 GO:0006952//defense response;GO:0007297//ovarian follicle cell migration;GO:0043409//negative regulation of MAPK cascade;GO:0001700//embryonic development via the syncytial blastoderm;GO:0042221//response to chemical stimulus;GO:0043409//negative regulation of MAPK cascade;GO:0031346//positive regulation of cell projection organization;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0006887//exocytosis;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0051668//localization within membrane;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051704;GO:0006952//defense response;GO:0042221//response to chemical stimulus;GO:0043409//negative regulation of MAPK cascade;GO:0031346//positive regulation of cell projection organization;GO:0051301//cell division;GO:0007297//ovarian follicle cell migration;GO:0006887//exocytosis;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0051668//localization within membrane;GO:0001700//embryonic development via the syncytial blastoderm;GO:0051704;GO:0006952//defense response 35943 2597.00 5.035 5.5 0.127439840405237 Up 0.15199445251618 CG8027 CG8027 K08239|1|4e-51|203|gga:418096|UDP-N-acetylglucosamine-lysosomal-enzyme [EC:2.7.8.17] GO:0044464//cell part GO:0046872//metal ion binding GO:0048869//cellular developmental process 19836209 1949.00 0.01 0.025 1.32192809488736 Up 0.0577202483159424 39413 3768.00 2.33 2.72 0.223276696596059 Up 0.158037247391362 CG32104 CG32104 - - - - 35803 557.00 0.655 0.735 0.166249343298914 Up 0.0753533218861445 CG14759 CG14759, isoform B - - - - 3772607 529.00 0.01 0.01 0 - 0.0382380134724607 His3:CG33827 histone H3 K11253|1|2e-71|266|dre:560616|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization 41280 1704.00 0.935 0.915 -0.0311946216035942 Down 0.0445449742438251 CG31391 CG31391 - - - - 44438 1725.59 59.195 57.97 -0.0301688358525317 Down 0.108539162594109 EfTuM elongation factor Tu mitochondrial, isoform B K02358|1|0.0|875|dme:Dmel_CG6050|elongation factor EF-Tu [EC:3.6.5.3] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0008135//translation factor activity, nucleic acid binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0006412//translation;GO:0006412//translation 36590 1942.00 1.045 1.02 -0.034933790109387 Down 0.0445449742438251 tej tejas - - GO:0016787//hydrolase activity;GO:0005488//binding - 35384 1879.31 17.73 17.71 -0.0016283241467741 Down 0.0416061286487914 CG9248 CG9248, isoform C - - - - 31004 4380.35 17.58 21.545 0.293418027966979 Up 0.432241447629111 CG13366 CG13366, isoform G K06115|1|1e-19|99.8|nve:NEMVE_v1g165235|spectrin beta - - - 41964 1392.43 101.445 31.23 -1.6996932851235 Down 0.769416193369436 CG8927 CG8927, isoform C - - - - 42305 1896.00 134.935 139.26 0.0455163194653614 Up 0.155791837273808 cry cryptochrome K02295|1|0.0|1101|dme:Dmel_CG3772|cryptochrome GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0030528//transcription regulator activity;GO:0004930//G-protein coupled receptor activity;GO:0030554//adenyl nucleotide binding;GO:0016830//carbon-carbon lyase activity;GO:0042302//structural constituent of cuticle;GO:0009881//photoreceptor activity GO:0048511//rhythmic process;GO:0007626//locomotory behavior;GO:0007602//phototransduction;GO:0006355//regulation of transcription, DNA-dependent;GO:0009629//response to gravity;GO:0006259//DNA metabolic process;GO:0009648//photoperiodism;GO:0006464//cellular protein modification process;GO:0050962//detection of light stimulus involved in sensory perception;GO:0006606//protein import into nucleus 38762 839.00 10.805 2.32 -2.21950236173193 Down 0.706742834500066 Mis12 Mis12 - GO:0000776//kinetochore - GO:0000070//mitotic sister chromatid segregation 40556 1718.00 24.515 23.11 -0.0851475018180544 Down 0.195879012019548 CG9855 CG9855, isoform C K10660|1|0.0|743|dme:Dmel_CG9855|E3 ubiquitin-protein ligase MARCH5 [EC:6.3.2.19] - GO:0046914//transition metal ion binding - 3772655 761.16 68.685 76.345 0.152538609149204 Up 0.335292563730022 CG33155 CG33155, isoform D K11593|1|3e-16|85.9|dsi:Dsim_GD25729|eukaryotic translation initiation factor 2C - - - 39392 1742.80 280.305 196.895 -0.509571003426937 Down 0.647404570070004 Est-6 esterase 6, isoform B K01044|1|0.0|1113|dme:Dmel_CG6917|carboxylesterase [EC:3.1.1.1] - GO:0016788//hydrolase activity, acting on ester bonds GO:0007292//female gamete generation;GO:0042446//hormone biosynthetic process;GO:0046692//sperm competition;GO:0045297//post-mating behavior;GO:0050795//regulation of behavior 31009 518.87 1223.95 1177.44 -0.0558910783639246 Down 0.185675604279488 RpL36 ribosomal protein L36, isoform E K02920|1|3e-59|227|dse:Dsec_GM19031|large subunit ribosomal protein L36e - - - 42709 744.55 44.525 46.04 0.0482722221432491 Up 0.144894994056267 CG17244 CG17244, isoform B - - - - 43765 5186.28 16.76 18.215 0.12010484604343 Up 0.22856954167217 Map205 Microtubule-associated protein 205, isoform C - GO:0005819//spindle;GO:0005874//microtubule;GO:0005819//spindle;GO:0005874//microtubule GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0009987//cellular process;GO:0009987//cellular process 5740596 407.15 283.585 86.77 -1.70851299012826 Down 0.779124290054154 CG34166 CG34166, isoform D - - - - 42564 1415.52 55.885 33.52 -0.737438954611006 Down 0.67504292695813 tsl torso-like, isoform C K12377|1|0.0|703|dme:Dmel_CG6705|torso-like protein - GO:0005102//receptor binding;GO:0005102//receptor binding GO:0000578//embryonic axis specification;GO:0000578//embryonic axis specification 35767 1268.00 0.81 1.95 1.26748031086499 Up 0.380398890503236 Odc2 ornithine decarboxylase 2 K01581|1|0.0|729|dme:Dmel_CG8719|ornithine decarboxylase [EC:4.1.1.17] - GO:0016831//carboxy-lyase activity GO:0006595//polyamine metabolic process 41337 810.00 0.15 0.165 0.137503523749935 Up 0.049861312904504 CG18577 CG18577 - - - - 42260 1032.00 1.98 3.12 0.656045598782639 Up 0.338759741117422 CG14297 CG14297 K01104|1|6e-137|486|dme:Dmel_CG14297|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044424//intracellular part GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 31860 597.00 6.485 18.66 1.52477050660006 Up 0.705256901334038 Obp8a Odorant-binding protein 8a - - GO:0005488//binding GO:0051234//establishment of localization 34408 2268.14 42.265 46.865 0.149047432803665 Up 0.320829480914014 dpr19 dpr19, isoform C - - - - 38972 881.00 34.24 65.245 0.930184644363433 Up 0.705355963545106 GstO3 glutathione S transferase O3 K00310|1|1e-81|303|dme:Dmel_CG6781|pyrimidodiazepine synthase [EC:1.5.4.1];K00799|1|1e-81|303|dme:Dmel_CG6781|glutathione S-transferase [EC:2.5.1.18] GO:0044424//intracellular part GO:0042802//identical protein binding;GO:0016648;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0019889//pteridine metabolic process;GO:0042441//eye pigment metabolic process;GO:0019725//cellular homeostasis 3772352 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 3355106 1290.00 40.09 35.49 -0.175829843089826 Down 0.354939902258618 Alg-2 Apoptosis-linked gene-2 K08585|1|8e-20|98.2|nvi:100119123|calpain, invertebrate [EC:3.4.22.-];K08573|3|2e-17|90.1|tgu:100225837|calpain-3 [EC:3.4.22.54];K08583|4|5e-17|89.0|bta:281664|calpain, small subunit 1;K13510|5|5e-17|89.0|ptr:454095|lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] - GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032559 GO:0012501//programmed cell death;GO:0043410//positive regulation of MAPK cascade;GO:0006464//cellular protein modification process 10178960 1868.00 4.63 5.965 0.365509944434992 Up 0.330174349491481 pre-mod(mdg4)-AE pre-mod(mdg4)-AE - GO:0000228//nuclear chromosome;GO:0044427//chromosomal part;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0030528//transcription regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0006333//chromatin assembly or disassembly;GO:0007292//female gamete generation;GO:0007140//male meiosis 42825 1978.00 4.43 4.96 0.163033421831857 Up 0.171080438515388 CG5857 Ndc1 ortholog - GO:0005635//nuclear envelope;GO:0031224//intrinsic to membrane - GO:0006810//transport;GO:0033036 2768944 4685.00 23.16 25.92 0.162430464895388 Up 0.308413683793422 rho-5 rhomboid-5 K10380|1|9e-26|120|dvi:Dvir_GJ19213|ankyrin;K02857|2|9e-07|57.0|cin:100180919|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic to membrane GO:0004175//endopeptidase activity GO:0023060 326124 915.00 231.4 135.34 -0.773800570785285 Down 0.705355963545106 CG31200 CG31200 K08670|1|3e-09|62.4|xla:394363|suppressor of tumorigenicity protein 14 [EC:3.4.21.109];K01314|2|3e-09|62.4|tgu:100221743|coagulation factor X [EC:3.4.21.6];K09640|3|4e-09|62.0|hsa:360200|transmembrane protease, serine 9 [EC:3.4.21.-];K01362|4|5e-09|61.6|dme:Dmel_CG4920| [EC:3.4.21.-];K01312|5|2e-08|60.1|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 32159 1914.00 0.025 0.03 0.263034405833794 Up 0.0467903843613789 gd gastrulation-defective, isoform E - - - - 31323 597.00 0.07 0.305 2.12338241550528 Up 0.184354774798574 CG13021 CG13021, isoform B - - - - 34011 2375.00 0.825 0.875 0.084888897586513 Up 0.0567956676793026 Wnt10 Wnt oncogene analog 10 K01357|1|0.0|819|dse:Dsec_GM16392|wingless-type MMTV integration site family, member 10 GO:0031012//extracellular matrix GO:0060089 GO:0009987//cellular process;GO:0035567//non-canonical Wnt receptor signaling pathway;GO:0048513//organ development;GO:0009653//anatomical structure morphogenesis 41271 1829.00 4.56 5.13 0.169925001442312 Up 0.180062078985603 CG6345 CG6345 - GO:0044424//intracellular part GO:0003824//catalytic activity;GO:0051536//iron-sulfur cluster binding GO:0008033//tRNA processing 5740826 482.00 3.29 3.03 -0.11876979026229 Down 0.111643111874257 CG34189 CG34189 - - - - 33309 802.00 0.835 1.49 0.83546422798811 Up 0.272685246334698 CG5139 CG5139 - - - - 32728 2647.00 0.3 0.375 0.321928094887362 Up 0.0850614185708625 CG8568 CG8568 - - - - 40047 1124.00 2.875 4.17 0.536485427612926 Up 0.348732003698323 HipHop HP1-HOAP-interacting protein, isoform B - - - - 42421 1198.00 7.56 21.105 1.48112668973662 Up 0.709483555672963 CG4335 CG4335 K00471|1|0.0|750|dme:Dmel_CG4335|gamma-butyrobetaine dioxygenase [EC:1.14.11.1];K00474|2|7e-66|251|ecb:100062170|trimethyllysine dioxygenase [EC:1.14.11.8] - GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0009437//carnitine metabolic process 33603 606.00 0.08 0.08 0 - 0.0382380134724607 CG31958 CG31958 K02183|1|8e-27|119|bta:514457|calmodulin - GO:0005488//binding - 37606 1771.00 0.13 0.1 -0.37851162325373 Down 0.0612534671773874 CG30259 CG30259 K10352|1|4e-09|63.2|smm:Smp_085540.6|myosin heavy chain - - - 36080 960.18 106.87 87.005 -0.296686706715211 Down 0.519515255580505 Syb synaptobrevin, isoform E K13504|1|1e-18|94.0|phu:Phum_PHUM576430|vesicle-associated membrane protein 2 GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic to membrane;GO:0030136//clathrin-coated vesicle GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0035148//tube formation;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0035148//tube formation;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0035148//tube formation;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis;GO:0035148//tube formation;GO:0001505//regulation of neurotransmitter levels;GO:0006904//vesicle docking involved in exocytosis 31529 1408.00 38.195 28.705 -0.412081735863052 Down 0.555045568617092 CG6067 CG6067 K01362|1|9e-10|65.1|dme:Dmel_CG14780| [EC:3.4.21.-] - - - 40090 5192.38 28.325 21.545 -0.394722857597495 Down 0.526020340774006 fz2 frizzled 2, isoform G K04690|1|0.0|1218|dme:Dmel_CG9739|frizzled, invertebrate GO:0031224//intrinsic to membrane;GO:0005768//endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0005768//endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0005768//endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031224//intrinsic to membrane;GO:0005768//endosome;GO:0016023//cytoplasmic membrane-bounded vesicle GO:0019904//protein domain specific binding;GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding;GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding;GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding;GO:0004888//transmembrane signaling receptor activity GO:0043062//extracellular structure organization;GO:0023060;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048588//developmental cell growth;GO:0006897//endocytosis;GO:0007431//salivary gland development;GO:0008406//gonad development;GO:0007166//cell surface receptor signaling pathway;GO:0043062//extracellular structure organization;GO:0023060;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048588//developmental cell growth;GO:0006897//endocytosis;GO:0007431//salivary gland development;GO:0008406//gonad development;GO:0007166//cell surface receptor signaling pathway;GO:0043062//extracellular structure organization;GO:0023060;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048588//developmental cell growth;GO:0006897//endocytosis;GO:0007431//salivary gland development;GO:0008406//gonad development;GO:0007166//cell surface receptor signaling pathway;GO:0043062//extracellular structure organization;GO:0023060;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0048588//developmental cell growth;GO:0006897//endocytosis;GO:0007431//salivary gland development;GO:0008406//gonad development;GO:0007166//cell surface receptor signaling pathway 39504 1112.72 4.675 4.74 0.0199206941232601 Up 0.0542200501915203 CG10222 CG10222, isoform B K06883|1|8e-164|576|dme:Dmel_CG10222| - GO:0005488//binding - 35850 1450.36 24.665 24.645 -0.00117030632326196 Down 0.0416061286487914 CG8635 CG8635, isoform B - - GO:0046872//metal ion binding - 38510 890.00 2.695 1.3 -1.05177364972405 Down 0.405461629903579 Cpr64Ac cuticular protein 64Ac - - GO:0042302//structural constituent of cuticle - 39345 1845.00 0.065 0.075 0.206450877467427 Up 0.045898824461762 CG14127 Coiled-coil domain containing protein 151 K09291|1|3e-07|57.0|tca:655393|nucleoprotein TPR;K12824|3|2e-06|54.7|cbr:CBG11210|transcription elongation regulator 1 - - - 36234 2174.00 2.975 2.24 -0.409390936137701 Down 0.252245410117554 CG7759 CG7759 K11426|1|1e-17|92.0|tgu:100230503|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0046914//transition metal ion binding GO:0006350 33896 7017.99 13.375 12.165 -0.136802571237443 Down 0.232895258222164 Tig tiggrin, isoform B K11498|1|3e-18|95.9|mdo:100013897|centromeric protein E;K10388|3|3e-17|92.4|hsa:5339|plectin - - - 33449 830.00 0.475 0.32 -0.569855608330948 Down 0.116398098005547 Prosbeta4R1 proteasome beta4 subunit-related 1 K02734|1|9e-123|439|dme:Dmel_CG17301|20S proteasome subunit beta 4 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 42790 1215.00 0.2 0.165 -0.277533975528909 Down 0.0642253335094439 CG16710 CG16710 K01362|1|5e-74|278|dme:Dmel_CG12133| [EC:3.4.21.-];K01312|4|5e-35|148|dpo:Dpse_GA15202|trypsin [EC:3.4.21.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process 42721 1433.00 35.225 29.985 -0.232358733731215 Down 0.408169330339453 CG17121 CG17121 K11151|1|7e-34|145|cfa:486998|retinol dehydrogenase 10 [EC:1.1.1.-] - GO:0003824//catalytic activity GO:0008152//metabolic process 35319 1038.00 1.085 2.885 1.410876276201 Up 0.467012283714173 CG15475 CG15475 - - - - 47905 4411.00 1.675 0.22 -2.92858566670784 Down 0.473649451855765 l(2)03659 lethal (2) 03659, isoform C K05673|1|0.0|1424|dpo:Dpse_GA18260|ATP-binding cassette, subfamily C (CFTR/MRP), member 4;K01509|2|0.0|1268|dme:Dmel_CG31793|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic to membrane GO:0015405;GO:0046914//transition metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032559 GO:0006810//transport 36050 460.00 26.585 29.815 0.165425870341329 Up 0.327466649055607 mRpL42 mitochondrial ribosomal protein L42, isoform B - GO:0000314//organellar small ribosomal subunit;GO:0000315//organellar large ribosomal subunit;GO:0000314//organellar small ribosomal subunit;GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression 19835292 582.00 0.29 0.65 1.16438681790088 Up 0.212191256108836 37397 957.00 9.875 7.88 -0.325585118495451 Down 0.375247655527671 CG4038 CG4038 K11128|1|4e-51|201|dme:Dmel_CG4038|H/ACA ribonucleoprotein complex subunit 1 - - - 33461 1516.33 377.565 353.195 -0.0962601144813425 Down 0.26413287544578 Pgk phosphoglycerate kinase, isoform E K00927|1|0.0|774|dme:Dmel_CG3127|phosphoglycerate kinase [EC:2.7.2.3] GO:0044424//intracellular part GO:0016301//kinase activity GO:0007267//cell-cell signaling;GO:0006007//glucose catabolic process 42728 1428.65 7.33 6.695 -0.130729142809502 Down 0.176330735702021 CG6726 CG6726, isoform C K01436|1|0.0|812|dme:Dmel_CG6726|aminoacylase [EC:3.5.1.14] GO:0044424//intracellular part;GO:0044424//intracellular part GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides GO:0019538//protein metabolic process;GO:0006519;GO:0019538//protein metabolic process;GO:0006519 42057 1185.00 8.05 8.105 0.00982340251556225 Up 0.0492999603751156 CG3995 CG3995 - - - - 19835129 547.00 0.08 0.01 -3 Down 0.110718531237617 8673965 3070.00 12.59 12.105 -0.05667520372008 Down 0.121879540351341 CG42638 CG42638 K04994|1|2e-107|390|mmu:171166|mucolipin 3 - GO:0030247//polysaccharide binding;GO:0016787//hydrolase activity GO:0006022 31015 5824.03 21.83 24.14 0.14511354576423 Up 0.288105930524369 Hmt4-20 histone methyltransferase 4-20, isoform B K11429|1|0.0|1463|dme:Dmel_CG13363|histone-lysine N-methyltransferase SUV420H [EC:2.1.1.43] - - - 40280 787.00 29.295 21.715 -0.431962497154055 Down 0.548507462686567 CG5104 CG5104 - - - GO:0006810//transport 37191 4026.00 6.355 8.73 0.458089528624481 Up 0.429599788667283 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B, isoform E K04164|1|3e-158|559|dme:Dmel_CG15113|5-hydroxytryptamine (serotonin) receptor, invertebrate GO:0016021//integral to membrane GO:0004993//serotonin receptor activity GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0042749//regulation of circadian sleep/wake cycle;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0009605//response to external stimulus 14462867 389.00 0.23 0.25 0.120294233717712 Up 0.0484744419495443 318251 563.00 11.445 12.535 0.131244533278252 Up 0.218002905824858 CG32856 CG32856, isoform B - - - - 43797 2051.60 263.015 256.985 -0.0334609271872872 Down 0.115209351472725 Pur-alpha Purine-rich binding protein-alpha, isoform G - - - - 42624 4186.84 5.505 8.23 0.580149866857257 Up 0.470908730682869 CG43343 CG43343, isoform C K00006|1|5e-83|310|dgr:Dgri_GH11012|glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part;GO:0043234//protein complex;GO:0044424//intracellular part GO:0003676//nucleic acid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding;GO:0000166//nucleotide binding GO:0006072//glycerol-3-phosphate metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006072//glycerol-3-phosphate metabolic process 50208 383.00 184.58 167.15 -0.143102884572355 Down 0.334268920882314 CG16836 CG16836 - - - - 37736 938.00 0.955 1.015 0.0879070891494273 Up 0.0601637828556333 CG5398 CG5398 K09884|1|3e-136|484|dme:Dmel_CG5398|aquaporin rerated protein, invertebrate GO:0031224//intrinsic to membrane GO:0022803 GO:0003008;GO:0006810//transport 33300 1925.00 4.14 4.6 0.15200309344505 Up 0.157872143706248 CG4785 integrator 14 - - - - 40056 3336.07 143.62 134.9 -0.0903663193405206 Down 0.237815348038568 CG3961 CG3961, isoform E K01897|1|0.0|1304|dme:Dmel_CG3961|long-chain acyl-CoA synthetase [EC:6.2.1.3] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - 38135 3871.00 0.08 0.185 1.20945336562895 Up 0.108142913749835 Klp61F Kinesin-like protein at 61F K10398|1|0.0|1855|dme:Dmel_CG9191|kinesin family member 11 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005871//kinesin complex GO:0003777//microtubule motor activity;GO:0032559 GO:0051260//protein homooligomerization;GO:0051012//microtubule sliding;GO:0051297//centrosome organization;GO:0007067//mitosis 37413 588.00 15.44 14.035 -0.137643688755556 Down 0.243792101439704 LSm1 LSm1 K12620|1|8e-65|245|dya:Dyak_GE13737|U6 snRNA-associated Sm-like protein LSm1 - - - 19834902 547.00 0.155 0.01 -3.95419631038688 Down 0.171410645885616 33771 1213.00 0.71 0.605 -0.230883882230088 Down 0.0839056927750627 CG14020 CG14020, isoform B - - - - 42394 2176.00 3.37 2.61 -0.368698784611974 Down 0.253797384757628 CG10889 CG10889 - - GO:0046914//transition metal ion binding - 2768946 1307.00 0.475 0.6 0.337034987277571 Up 0.0998547087570995 CG33278 CG33278 - - - - 14462493 1154.00 2.61 2.43 -0.103093492964104 Down 0.0902126535464272 35693 10364.00 13.095 12.525 -0.0642054562680256 Down 0.128945978074231 Vps13 vacuolar protein sorting 13, isoform B - - - GO:0033036 12798224 1060.00 0.07 0.125 0.836501267717121 Up 0.07657508915599 38591 767.00 0.72 1.555 1.11084576868829 Up 0.323801347246071 CG17030 CG17030 K04552|1|2e-40|166|dwi:Dwil_GK22072|ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19] - GO:0005488//binding;GO:0019787//small conjugating protein ligase activity GO:0060255;GO:0006464//cellular protein modification process 31039 1301.00 0.18 0.525 1.54432051622381 Up 0.215196143177916 CG3708 CG3708 K11282|1|0.0|719|dme:Dmel_CG3708|nucleosome assembly protein 1-like 4;K11279|2|0.0|669|dse:Dsec_GM19012|nucleosome assembly protein 1-like 1 - - - 12798556 603.00 0.405 0.08 -2.33985000288462 Down 0.222691850482103 CG43055 CG43055 - - - - 34356 772.00 19.15 16.85 -0.184595800743098 Down 0.312970545502576 CG5727 CG5727 - - GO:0003676//nucleic acid binding - 10178847 500.00 13.615 6 -1.18216257654792 Down 0.652654867256637 CG42662 CG42662, isoform D - - GO:0004175//endopeptidase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0006351//transcription, DNA-dependent;GO:0019538//protein metabolic process;GO:0006351//transcription, DNA-dependent 19835183 447.00 0.105 0.11 0.0671141958585367 Up 0.0382380134724607 14462485 1247.08 3.925 4.38 0.158238215822184 Up 0.159919429401664 koko kokopelli, isoform E - - - GO:0042078//germ-line stem cell division;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0042078//germ-line stem cell division;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0042078//germ-line stem cell division;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0042078//germ-line stem cell division;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway 32011 791.00 191.68 293.36 0.61397235792288 Up 0.676099590542861 CG15209 CG15209 - - - - 48582 2347.00 454.595 214.79 -1.08165498914092 Down 0.743527935543521 Hsp70Bb Heat-shock-protein-70Bb K03283|1|0.0|1147|dme:Dmel_CG31359|heat shock 70kDa protein 1/8 GO:0015630//microtubule cytoskeleton GO:0032559 GO:0034605//cellular response to heat 42361 973.10 30.95 31.55 0.0277005957682842 Up 0.099524501386871 CG4686 CG4686, isoform B - - - - 37430 336.32 756.115 827.485 0.130127484775628 Up 0.324791969356756 RpL29 ribosomal protein L29, isoform D K02905|1|2e-38|157|dsi:Dsim_GD11583|large subunit ribosomal protein L29e - - - 3346225 1405.00 0.615 1.84 1.58104745071777 Up 0.408862765816933 CG33509 CG33509 - - - - 33094 2244.32 21.865 14.75 -0.567908393944642 Down 0.581693303394532 CG15445 CG15445, isoform H - - - - 39462 1150.00 0.54 0.115 -2.23132554610646 Down 0.256439043719456 CG10943 CG10943 K11499|1|3e-08|58.9|ptr:457733|centromere protein F;K12478|4|1e-07|57.0|cfa:475424|early endosome antigen 1;K11498|5|2e-07|56.6|der:Dere_GG10315|centromeric protein E - - - 36163 1371.74 17.03 26.21 0.622038918649875 Up 0.60959582617884 Spn47C serpin 47C, isoform C K13963|1|1e-74|280|dwi:Dwil_GK20885|serpin B - GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity - 37282 2301.17 64.275 66.675 0.0528882147172701 Up 0.15106987187954 CG11099 CG11099, isoform B K12796|1|4e-16|87.0|ame:410256|erbb2-interacting protein - - - 35612 1025.00 0.57 0.45 -0.341036917835067 Down 0.0998547087570995 Tsp42Ec tetraspanin 42Ec K06497|1|3e-42|172|dme:Dmel_CG30160|CD63 antigen GO:0031224//intrinsic to membrane - - 3772522 135.00 0.01 0.015 0.584962500721156 Up 0.0382380134724607 39511 969.00 0.045 0.1 1.15200309344505 Up 0.0796790384361379 CG10140 CG10140 K01873|1|3e-26|119|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9];K01183|5|3e-06|52.8|dme:Dmel_CG18140|chitinase [EC:3.2.1.14] - GO:0030247//polysaccharide binding GO:0006022 39423 1524.00 56.435 30.93 -0.867583340993773 Down 0.693369436005812 CG10657 CG10657 K10693|1|3e-15|83.2|dpe:Dper_GL26848|E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19];K01104|2|4e-09|63.2|dmo:Dmoj_GI14758|protein-tyrosine phosphatase [EC:3.1.3.48] GO:0044464//cell part - GO:0051234//establishment of localization 35575 1449.00 46.005 35.32 -0.38130532433971 Down 0.548903711530841 CG3270 CG3270 K00315|1|1e-07|58.2|isc:IscW_ISCW001817|dimethylglycine dehydrogenase [EC:1.5.99.2];K00306|2|9e-07|55.1|bfo:BRAFLDRAFT_114735|sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7] - GO:0003824//catalytic activity - 50002 621.00 488.49 459.29 -0.0889236562454972 Down 0.245046889446572 CG9603 CG9603, isoform B K02270|1|1e-43|175|dme:Dmel_CG9603|cytochrome c oxidase subunit VIIa [EC:1.9.3.1] GO:0005743//mitochondrial inner membrane GO:0015002//heme-copper terminal oxidase activity GO:0022904//respiratory electron transport chain 34547 953.00 0.42 0.46 0.131244533278253 Up 0.0577532690529653 CG14921 CG14921 - GO:0005753//mitochondrial proton-transporting ATP synthase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process 39455 4045.92 17.53 18.67 0.0908959314666641 Up 0.186071853123762 Sap130 Sin3A-associated protein 130, isoform G - - - - 338395 1279.00 2.745 3.015 0.135351852894886 Up 0.119039756967376 CG33213 CG33213 K09228|1|2e-10|67.4|ptr:456332|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - 19836238 730.00 211.58 78.8 -1.42493572562311 Down 0.762118610487386 40140 4244.03 10.75 12.165 0.178399660461606 Up 0.269878483687756 l(3)76BDm lethal (3) 76BDm, isoform B - - - - 43236 1858.00 5.64 5.72 0.0203199843795962 Up 0.0559701492537313 Ets97D Ets at 97D, isoform B K09441|1|0.0|823|dme:Dmel_CG6338|GA-binding protein transcription factor, alpha GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0019094//pole plasm mRNA localization;GO:0006355//regulation of transcription, DNA-dependent 36448 1767.38 30.83 33.765 0.131193668068137 Up 0.280313036586977 Spt-I serine palmitoyltransferase subunit I, isoform C K00654|1|0.0|850|dme:Dmel_CG4016|serine palmitoyltransferase [EC:2.3.1.50] - GO:0016454;GO:0048037//cofactor binding;GO:0016454;GO:0048037//cofactor binding;GO:0016454;GO:0048037//cofactor binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process 42294 1697.00 67.975 49.04 -0.471045267221341 Down 0.607284374587241 Cyp12a4 Cyp12a4 K00517|1|0.0|1076|dme:Dmel_CG6042| [EC:1.14.-.-];K10723|5|2e-47|190|dme:Dmel_CG13478|CYP314A1; ecdysone 20-monooxygenase [EC:1.14.99.22] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding GO:0008152//metabolic process;GO:0009636//response to toxic substance 19835902 3040.24 14.255 17.84 0.323647575982352 Up 0.440661735569938 - CG45086, isoform B - - - - 42833 1767.51 33.32 16.075 -1.05156966315024 Down 0.695912032756571 CG12268 CG12268, isoform C K13356|1|4e-145|514|aga:AgaP_AGAP002279|fatty acyl-CoA reductase [EC:1.2.1.-] - - - 39070 715.00 10.89 13.875 0.349483817407924 Up 0.432439572051248 Fdxh ferredoxin, isoform B - - GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding - 36019 2523.00 8.1 6.145 -0.398508897399325 Down 0.38947959318452 CG1671 CG1671 K03362|1|1e-22|108|cin:445628|F-box and WD-40 domain protein 1/11;K10260|3|5e-21|103|hmg:100201874|F-box and WD-40 domain protein 7 GO:0030684//preribosome - GO:0042254//ribosome biogenesis 37446 2252.00 6.81 5.115 -0.412920558266743 Down 0.370690793818518 Acox57D-d acyl-Coenzyme A oxidase at 57D distal K00232|1|0.0|1281|dme:Dmel_CG9709|acyl-CoA oxidase [EC:1.3.3.6] - - - 35826 1795.00 0.295 0.705 1.25690830303695 Up 0.230517765156518 Mal-A3 maltase A3 K01187|1|0.0|1144|dme:Dmel_CG8695|alpha-glucosidase [EC:3.2.1.20] - GO:0043167//ion binding;GO:0015926//glucosidase activity GO:0019318//hexose metabolic process 31308 1659.00 0.14 0.26 0.893084796083488 Up 0.113096024303262 CG10793 CG10793 K07767|1|3e-52|206|tad:TRIADDRAFT_25144|microtubule-severing ATPase [EC:3.6.4.3] - - - 33887 1392.00 0.085 0.065 -0.387023123109247 Down 0.0544181746136574 ppk14 pickpocket 14 K04829|1|3e-06|53.1|spu:575477|amiloride-sensitive cation channel 2, neuronal GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 43443 604.00 7.79 8.255 0.0836448868515892 Up 0.132082948091401 CG14512 CG14512 K07432|1|3e-94|343|dme:Dmel_CG14512|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141] - GO:0005488//binding;GO:0016757//transferase activity, transferring glycosyl groups GO:0030258//lipid modification 36793 5896.00 17.765 18.405 0.051060061052839 Up 0.124257033416986 clu clueless, isoform B K03255|1|0.0|2474|dme:Dmel_CG8443|translation initiation factor eIF-3 subunit P135 GO:0043234//protein complex GO:0008135//translation factor activity, nucleic acid binding - 38495 536.00 0.385 0.445 0.208946890271496 Up 0.0691124025888258 Akh adipokinetic hormone - - GO:0005179//hormone activity GO:0007186//G-protein coupled receptor signaling pathway 251937 449.88 7.23 13.96 0.949231389258535 Up 0.623893805309734 CG31468 CG31468, isoform B - - - - 43835 2720.85 4.75 2.965 -0.679895408672307 Down 0.415268788799366 CORL fussel, isoform D - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding - 32646 2505.04 45.665 53.615 0.231547850196567 Up 0.427684585919958 Sep4 septin 4, isoform G K04557|1|5e-121|435|xla:779425|peanut-like protein 1 (cell division control related protein 1) GO:0032156;GO:0032156;GO:0032156;GO:0032156;GO:0032156;GO:0032156;GO:0032156 GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding GO:0051301//cell division;GO:0051301//cell division;GO:0051301//cell division;GO:0051301//cell division;GO:0051301//cell division;GO:0051301//cell division;GO:0051301//cell division 48312 541.00 26.655 22.655 -0.234576691236445 Down 0.390998547087571 RpII18 RNA polymerase II 18kD subunit K03014|1|2e-49|194|dya:Dyak_GE25464|DNA-directed RNA Polymerase II subunit F GO:0016591//DNA-directed RNA polymerase II, holoenzyme GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding GO:0006351//transcription, DNA-dependent 14462697 1094.00 0.01 0.12 3.58496250072116 Up 0.14562145027077 35160 1715.00 0.135 0.03 -2.16992500144231 Down 0.115209351472725 CG15170 CG15170, isoform B - - - - 39220 1213.43 377.23 385.375 0.0308185704345491 Up 0.115836745476159 CG6409 CG6409, isoform B K12831|1|6e-06|52.0|gga:426042|splicing factor 3B subunit 4 - - GO:0006497//protein lipidation 42343 1250.00 18.415 19.03 0.0473941643742841 Up 0.123068286884163 CG6195 CG6195 K06944|1|0.0|697|dsi:Dsim_GD20106| GO:0044464//cell part GO:0032561//guanyl ribonucleotide binding - 19835502 255.00 0.57 0.21 -1.44057259138598 Down 0.219653942676001 38096 1184.42 89.82 85.03 -0.0790647842174281 Down 0.212554484216088 CG13887 CG13887, isoform E K14009|1|2e-116|418|dme:Dmel_CG13887|B-cell receptor-associated protein 31 GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic to membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0015031//protein transport;GO:0015031//protein transport 38970 990.00 4.45 4.75 0.09412217736455 Up 0.111180821555937 CG6683 CG6683 - - - - 31845 923.00 8.97 12.51 0.479901899246559 Up 0.488079513934751 fh frataxin homolog, isoform B - GO:0043231//intracellular membrane-bounded organelle GO:0005506//iron ion binding GO:0030005;GO:0000302//response to reactive oxygen species 41029 1021.00 15.18 14.705 -0.0458650065284022 Down 0.114119667150971 CG9773 CG9773 - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - - 42124 5747.65 6.96 8.175 0.232131424536717 Up 0.276713776251486 CG14322 CG14322, isoform E K09566|1|7e-08|60.8|gga:424162|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8];K13171|2|1e-06|57.0|phu:Phum_PHUM150090|serine/arginine repetitive matrix protein 1;K13165|3|1e-06|56.6|cqu:CpipJ_CPIJ018619|splicing factor, arginine/serine-rich 12;K12893|4|1e-06|56.6|xla:379840|splicing factor, arginine/serine-rich 4/5/6;K13206|5|1e-06|56.6|tgu:100231030|coiled-coil domain-containing protein 55 - - - 32782 3196.00 10.41 11.145 0.0984265479603353 Up 0.169330339453177 CG6867 CG6867 K08132|1|3e-21|104|tgu:100226890|collagen, type XII, alpha - - - 42092 950.69 68.415 45.34 -0.593528279838125 Down 0.64747061154405 CREG cellular repressor of E1A-stimulated genes, isoform D - - - - 37792 1671.00 5.895 5.36 -0.13725881252199 Down 0.166919825650509 Upf3 Upf3, isoform D - - - - 31032 475.00 0.27 0.295 0.127755547198373 Up 0.0491348566900013 CG14635 CG14635 - - - - 43201 757.00 0.055 0.065 0.241008099503795 Up 0.0461960110949676 TwdlP TweedleP - - - - 44058 2187.84 5.965 7.635 0.356106019101624 Up 0.358241975960903 Dot dorothy, isoform B K00699|1|1e-81|304|dme:Dmel_CG17323|glucuronosyltransferase [EC:2.4.1.17] - GO:0016757//transferase activity, transferring glycosyl groups - 5740208 575.00 247.325 278.73 0.172460212584976 Up 0.384130233786818 8674080 617.00 0.485 0.345 -0.491388385408959 Down 0.111742174085326 CG42512 CG42512, isoform B - - - - 37407 1347.00 8.41 7.4 -0.184580529738832 Down 0.236461497820631 CG9418 high mobility group protein 2 K09273|1|2e-08|60.8|ecb:100064724|upstream-binding transcription factor - - - 33257 896.00 1.415 1.635 0.2084885826662 Up 0.115539558842953 CG15880 CG15880 - GO:0044464//cell part - - 14462506 1175.00 5.045 3.045 -0.728412041200025 Down 0.440232465988641 40593 1906.82 15.855 17.32 0.127501052622886 Up 0.239268260467574 atms antimeros, isoform B - - - - 43743 2021.00 0.23 0.11 -1.06413033741972 Down 0.117487782327302 CG2187 CG2187, isoform B K03307|1|4e-101|369|dme:Dmel_CG6723|solute:Na+ symporter, SSS family GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane - GO:0030001//metal ion transport;GO:0030001//metal ion transport 19835729 753.00 0.105 0.075 -0.485426827170241 Down 0.0618808611808216 40779 745.00 1.225 1.185 -0.0478946901043115 Down 0.051182142385418 CG10298 CG10298 - - - - 5740203 1341.51 5.505 6.26 0.185420093368249 Up 0.211960110949676 CG34179 CG34179, isoform C - GO:0043231//intracellular membrane-bounded organelle - GO:0014821;GO:0007610//behavior;GO:0048232//male gamete generation 19835714 351.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 40177 1797.00 23.73 20.69 -0.197778455333939 Down 0.350019812442214 Grasp65 Grasp65 - GO:0044431//Golgi apparatus part;GO:0016023//cytoplasmic membrane-bounded vesicle GO:0005488//binding GO:0006996//organelle organization 33129 1819.54 9.085 10.42 0.197796858044392 Up 0.274534407607978 CG14615 CG14615, isoform B - - - - 5740389 321.00 113.39 112.755 -0.00810200321621433 Down 0.0675934486857747 CG34200 CG34200 - - - - 34632 1089.00 1.27 1.045 -0.281325554691283 Down 0.12627129837538 Mt2 methyltransferase 2, isoform D K00558|1|0.0|641|dme:Dmel_CG10692|DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37] GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0003676//nucleic acid binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0001510//RNA methylation;GO:0010259//multicellular organismal aging;GO:0044030//regulation of DNA methylation;GO:0001510//RNA methylation;GO:0010259//multicellular organismal aging;GO:0044030//regulation of DNA methylation 43229 931.51 55.415 59.715 0.107816827347407 Up 0.262448817857615 His2Av histone H2A variant, isoform B K11251|1|5e-59|227|dsi:Dsim_GD21310|histone H2A GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding GO:0033554//cellular response to stress;GO:0034728//nucleosome organization 43804 2705.00 32.98 37.145 0.171576627313471 Up 0.340575881653679 mav maverick K04384|1|0.0|1235|dse:Dsec_GM26775|transforming growth factor beta, invertebrate - - - 31388 1086.37 47.765 45.31 -0.0761243737589748 Down 0.200964205521067 CG11444 CG11444, isoform B - - - - 37761 601.46 88.895 84.385 -0.0751157023217304 Down 0.211662924316471 CG5532 CG5532, isoform B - GO:0044464//cell part - - 36276 2965.03 22.36 10.055 -1.15300710653784 Down 0.684718002905825 CG13188 CG13188, isoform B K04500|1|2e-06|55.8|spu:577345|SMAD, mothers against DPP 2/3;K04676|2|6e-06|53.9|cbr:CBG06922|SMAD, mothers against DPP 1/5/8 GO:0044464//cell part;GO:0044464//cell part - GO:0006351//transcription, DNA-dependent;GO:0006351//transcription, DNA-dependent 39207 973.11 1.205 1.2 -0.00599874062144323 Down 0.041044776119403 CG14154 CG14154, isoform B - - - - 36742 2137.35 15 14.285 -0.0704614644468713 Down 0.14562145027077 CG8249 CG8249, isoform C K08145|1|3e-48|193|bfo:BRAFLDRAFT_82927|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 GO:0031224//intrinsic to membrane GO:0022857//transmembrane transporter activity GO:0006810//transport 3355136 6676.23 31.36 34.2 0.125070765658052 Up 0.2791903315282 Nipped-B Nipped-B, isoform J K06672|1|0.0|3811|dme:Dmel_CG17704|cohesin loading factor subunit SCC2 GO:0000798//nuclear cohesin complex;GO:0000785//chromatin;GO:0000798//nuclear cohesin complex;GO:0000785//chromatin;GO:0000798//nuclear cohesin complex;GO:0000785//chromatin;GO:0000798//nuclear cohesin complex;GO:0000785//chromatin;GO:0000798//nuclear cohesin complex;GO:0000785//chromatin GO:0030528//transcription regulator activity;GO:0003824//catalytic activity;GO:0030528//transcription regulator activity;GO:0003824//catalytic activity;GO:0030528//transcription regulator activity;GO:0003824//catalytic activity;GO:0030528//transcription regulator activity;GO:0003824//catalytic activity;GO:0030528//transcription regulator activity;GO:0003824//catalytic activity GO:0007064//mitotic sister chromatid cohesion;GO:0051304//chromosome separation;GO:0006351//transcription, DNA-dependent;GO:0007064//mitotic sister chromatid cohesion;GO:0051304//chromosome separation;GO:0006351//transcription, DNA-dependent;GO:0007064//mitotic sister chromatid cohesion;GO:0051304//chromosome separation;GO:0006351//transcription, DNA-dependent;GO:0007064//mitotic sister chromatid cohesion;GO:0051304//chromosome separation;GO:0006351//transcription, DNA-dependent;GO:0007064//mitotic sister chromatid cohesion;GO:0051304//chromosome separation;GO:0006351//transcription, DNA-dependent 40188 1704.21 289.365 299.08 0.0476410061959369 Up 0.159820367190596 CG7433 CG7433, isoform D K13524|1|0.0|952|dme:Dmel_CG7433|4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] GO:0031980;GO:0031980;GO:0031980 GO:0008483//transaminase activity;GO:0048037//cofactor binding;GO:0008483//transaminase activity;GO:0048037//cofactor binding;GO:0008483//transaminase activity;GO:0048037//cofactor binding GO:0006575//cellular modified amino acid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0006575//cellular modified amino acid metabolic process 3772329 592.00 8.45 8.185 -0.045968924695393 Down 0.0921278562937525 Chrac-14 chromatin accessibility complex 14kD protein K02326|1|8e-34|142|dme:Dmel_CG13399|DNA polymerase epsilon subunit 3 [EC:2.7.7.7] GO:0016585//chromatin remodeling complex GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0033554//cellular response to stress;GO:0034728//nucleosome organization 36974 2895.94 25.295 29.475 0.220639574059854 Up 0.3867058512746 CG4853 CG4853, isoform C K07376|1|9e-58|225|mcc:696308|protein kinase, cGMP-dependent [EC:2.7.11.12];K12326|2|6e-17|90.1|mmu:19418|Ras-specific guanine nucleotide-releasing factor 2 - - - 42513 1384.00 0.225 0.56 1.31550182572793 Up 0.210804385153877 CG5810 CG5810 K13023|1|6e-20|98.6|ecb:100069043|carboxypeptidase N regulatory subunit - GO:0005488//binding - 19835810 368.00 0.13 0.01 -3.70043971814109 Down 0.155263505481442 43200 1030.00 0.04 0.155 1.95419631038688 Up 0.124157971205917 TwdlM TweedleM - - - - 36386 2974.92 7.54 6.57 -0.198671152946335 Down 0.239532426363756 muskelin muskelin, isoform C - - - - 43581 3351.29 2.635 4.865 0.884636843143897 Up 0.471668207634394 Ppi1 protein phosphatase 1c interacting protein 1, isoform B - - - - 31838 2121.00 34.505 30.705 -0.168331829896424 Down 0.335853916259411 CG7033 CG7033 K09494|1|0.0|981|dme:Dmel_CG7033|T-complex protein 1 subunit beta GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0032559 GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0044267//cellular protein metabolic process 12797979 771.00 0.21 0.175 -0.263034405833794 Down 0.0589420155857879 CG43076 CG43076 - - - - 43362 6536.30 39.025 47.77 0.291706244605994 Up 0.48401796328094 CG34362 CG34362, isoform J K13201|1|1e-60|234|dre:394107|nucleolysin TIAR - GO:0005488//binding;GO:0005488//binding GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome 39464 872.50 0.01 0.105 3.39231742277876 Up 0.13426231673491 CG43894 CG43894, isoform E - - - - 32762 1124.00 8.465 8.03 -0.0761100803783269 Down 0.12696473385286 e(y)1 enhancer of yellow 1 K03133|1|8e-114|410|dme:Dmel_CG6474|transcription initiation factor TFIID subunit D7 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003702//RNA polymerase II transcription factor activity GO:0006352//DNA-dependent transcription, initiation;GO:0006355//regulation of transcription, DNA-dependent 32191 5380.32 10.615 8.7 -0.287017065169287 Down 0.354807819310527 Pkcdelta protein kinase C delta, isoform E K06068|1|0.0|722|dya:Dyak_GE17008|novel protein kinase C [EC:2.7.11.13] - GO:0043169//cation binding;GO:0008289//lipid binding;GO:0004672//protein kinase activity;GO:0032559;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0004672//protein kinase activity;GO:0032559;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0004674//protein serine/threonine kinase activity;GO:0032559 GO:0006464//cellular protein modification process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023033;GO:0006464//cellular protein modification process;GO:0023033 3771912 1023.00 0.01 0.145 3.85798099512757 Up 0.168967111345925 His1:CG33849 histone H1 K11275|1|3e-38|158|dsi:Dsim_GD14743|histone H1/5 GO:0043229//intracellular organelle - GO:0006325//chromatin organization 36766 981.00 4.265 4.52 0.0837770310968975 Up 0.0990952318055739 Rrp42 Rrp42 K12589|1|6e-162|569|dme:Dmel_CG8395|exosome complex component RRP42 GO:0000178//exosome (RNase complex);GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity GO:0010467//gene expression 40752 1161.00 0.01 0.19 4.24792751344359 Up 0.201558578787479 Osi1 osiris 1 - - - - 3354999 569.00 58.27 94.88 0.703350699198682 Up 0.679038436137895 CG41087 CG41087 - - GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis 318992 1089.00 11.72 10.67 -0.135412393597823 Down 0.220776647734777 Ada1-2 transcriptional adaptor 1-2 K11317|1|2e-149|528|dme:Dmel_CG31866|transcriptional adapter 1-like protein - GO:0003676//nucleic acid binding - 38216 2538.00 2.075 2.48 0.257228784152588 Up 0.165698058380663 CG18171 CG18171 - - - - 42530 5029.00 3.66 3.86 0.076757198984038 Up 0.0903117157574957 SIFR SIFamide receptor, isoform C K08375|1|7e-56|220|dre:560955|neuropeptide FF receptor 2;K04240|3|3e-54|214|mdo:100023203|neuropeptide FF receptor 1 GO:0031224//intrinsic to membrane;GO:0031224//intrinsic to membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007166//cell surface receptor signaling pathway;GO:0023060 32458 4069.36 29.98 33.145 0.144790869578129 Up 0.294908202351076 Top1 topoisomerase 1, isoform E K03163|1|0.0|998|dme:Dmel_CG6146|DNA topoisomerase I [EC:5.99.1.2] GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005700//polytene chromosome;GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005700//polytene chromosome GO:0003916//DNA topoisomerase activity;GO:0003916//DNA topoisomerase activity;GO:0016251//general RNA polymerase II transcription factor activity;GO:0003916//DNA topoisomerase activity GO:0051276//chromosome organization;GO:0002164//larval development;GO:0006261//DNA-dependent DNA replication;GO:0007292//female gamete generation;GO:0051276//chromosome organization;GO:0002164//larval development;GO:0006261//DNA-dependent DNA replication;GO:0007292//female gamete generation;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0002164//larval development;GO:0006261//DNA-dependent DNA replication;GO:0007292//female gamete generation 44913 753.18 2.88 3.37 0.226679779739546 Up 0.178708228767666 Acam androcam, isoform B K02183|1|3e-71|267|dsi:Dsim_GD21235|calmodulin GO:0016461//unconventional myosin complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016461//unconventional myosin complex;GO:0043231//intracellular membrane-bounded organelle GO:0032028//myosin head/neck binding;GO:0046872//metal ion binding;GO:0032028//myosin head/neck binding;GO:0046872//metal ion binding;GO:0016491//oxidoreductase activity GO:0009593//detection of chemical stimulus;GO:0009593//detection of chemical stimulus 246518 1899.19 2.085 2.885 0.468523935200819 Up 0.271001188746533 CG30271 CG30271, isoform I - - - - 44513 2228.00 0.45 0.48 0.0931094043914815 Up 0.0504226654338925 proPO59 prophenoloxidase 3 K00505|1|0.0|1392|dme:Dmel_CG42640|tyrosinase [EC:1.14.18.1] - GO:0016716//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;GO:0022892;GO:0043169//cation binding GO:0006582//melanin metabolic process;GO:0051234//establishment of localization 12798047 584.00 1.035 0.39 -1.40808473863708 Down 0.294776119402985 CG43290 CG43290 - - - - 32839 2217.58 14.485 13.59 -0.0920142285030121 Down 0.172830537577599 Ggt-1 gamma-glutamyl transpeptidase, isoform B K00681|1|0.0|1110|dme:Dmel_CG6461|gamma-glutamyltranspeptidase [EC:2.3.2.2] - GO:0016755 - 39610 5961.00 22.54 25.28 0.165508948004882 Up 0.317692510896843 mop myopic K01104|1|0.0|2942|dme:Dmel_CG9311|protein-tyrosine phosphatase [EC:3.1.3.48] - GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process 42268 1116.08 151.81 143.4 -0.0822218027822951 Down 0.218333113195087 Mpc1 mitochondrial pyruvate carrier, isoform C - - - - 42230 929.71 18.6 18.56 -0.00310591086782184 Down 0.0434552899220711 CG7694 CG7694, isoform C K11982|1|1e-12|72.8|dre:100009648|E3 ubiquitin-protein ligase RNF115/126 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 318753 981.00 2.4 3.855 0.683696454306515 Up 0.379903579447893 CG31473 CG31473 K00275|1|6e-152|536|dme:Dmel_CG31473|pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] - GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0000166//nucleotide binding GO:0008614//pyridoxine metabolic process 39539 1940.00 5.6 5.975 0.0935118859231446 Up 0.124455157839123 Meics meiotic central spindle, isoform B K09228|1|5e-80|298|ecb:100061107|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity - 59171 1168.00 1.085 1.685 0.635053548737379 Up 0.245905428609167 CG18810 CG18810 - - GO:0046914//transition metal ion binding - 36463 1020.00 10.025 9.07 -0.14442778081376 Down 0.213181878219522 fsd fates-shifted - - - - 117492 1161.00 0.04 0.01 -2 Down 0.0694426099590543 Gr22b gustatory receptor 22b K08471|1|0.0|777|dme:Dmel_CG31931|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 43594 727.35 1053.865 1038.75 -0.0208415927265657 Down 0.0939770175670321 RpS7 ribosomal protein S7, isoform E K02993|1|7e-105|379|dsi:Dsim_GD17201|small subunit ribosomal protein S7e GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex;GO:0044444//cytoplasmic part;GO:0030529//ribonucleoprotein complex GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression 36934 1484.73 0.8 1.47 0.877744249949002 Up 0.278628978998811 Cda9 chitin deacetylase-like 9, isoform B - - - - 40097 2053.00 42.28 35.945 -0.234184273006884 Down 0.418009509972263 CG9629 CG9629 K00128|1|0.0|1018|dme:Dmel_CG9629|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] - GO:0003824//catalytic activity GO:0008152//metabolic process 40745 1510.79 364.7 177.445 -1.03933827659573 Down 0.740490027737419 Gasp gasp, isoform B K01873|1|2e-11|70.9|tca:662504|valyl-tRNA synthetase [EC:6.1.1.9] - GO:0030247//polysaccharide binding;GO:0030247//polysaccharide binding GO:0006022;GO:0006022 37128 766.93 18.11 14.91 -0.280506288666726 Down 0.406815480121516 GstE11 glutathione S transferase E11, isoform B K00799|1|9e-46|183|dpo:Dpse_GA14540|glutathione S-transferase [EC:2.5.1.18] - - - 34826 8851.25 15.955 22.5 0.495916392825087 Up 0.558050455686171 nAcRalpha-34E nicotinic acetylcholine receptor alpha5, isoform H K05312|1|0.0|753|dme:Dmel_CG32975|nicotinic acetylcholine receptor, invertebrate;K04809|3|1e-138|495|dre:394199|nicotinic acetylcholine receptor alpha-7 GO:0030425//dendrite;GO:0005887//integral to plasma membrane;GO:0030425//dendrite;GO:0005887//integral to plasma membrane GO:0004871//signal transducer activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004871//signal transducer activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0051899//membrane depolarization;GO:0007610//behavior;GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0051899//membrane depolarization;GO:0007610//behavior 38323 641.00 22.295 22.32 0.00161682751528285 Up 0.0416061286487914 CG16985 CG16985 - - - - 37197 2343.56 10.69 8.69 -0.29883377090609 Down 0.364515915995245 CG15117 CG15117, isoform F K01195|1|0.0|1357|dsi:Dsim_GD25338|beta-glucuronidase [EC:3.2.1.31] - - - 36250 2033.00 0.27 0.415 0.620151929183456 Up 0.117685906749439 CG13196 CG13196 - - - - 43751 5079.00 10.6 10.725 0.0169133829363461 Up 0.0611544049663188 Acf1 ATP-dependent chromatin assembly factor large subunit K11655|1|0.0|2617|dme:Dmel_CG1966|bromodomain adjacent to zinc finger domain protein 1A GO:0005678//chromatin assembly complex;GO:0031010 GO:0046914//transition metal ion binding;GO:0004468//lysine N-acetyltransferase activity;GO:0003676//nucleic acid binding GO:0032583;GO:0009888//tissue development;GO:0048812//neuron projection morphogenesis;GO:0006333//chromatin assembly or disassembly;GO:0034728//nucleosome organization;GO:0033121;GO:0048513//organ development 40711 1335.00 9.33 9.49 0.0245310061693505 Up 0.0657773081495179 CG2091 CG2091 K12584|1|0.0|754|dme:Dmel_CG2091|scavenger mRNA-decapping enzyme DcpS [EC:3.-.-.-] - GO:0003824//catalytic activity;GO:0005488//binding GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 45960 1775.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 aly always early, isoform B - - - - 14462650 754.00 5.5 5.935 0.109816411229885 Up 0.141229692246731 37582 3781.00 0.69 1 0.535331732996555 Up 0.169396380927222 CG4329 CG4329 K11499|1|2e-13|78.6|ecb:100050180|centromere protein F;K10352|2|6e-11|70.5|dre:555454|myosin heavy chain;K11498|5|8e-11|70.1|mcc:711186|centromeric protein E GO:0044464//cell part GO:0042625//ATPase activity, coupled to transmembrane movement of ions;GO:0032559 GO:0009206 31902 2360.00 16.07 15.4 -0.0614395780928301 Down 0.135352001056664 Gga Golgi-localized, gamma-adaptin ear containing, ARF binding protein K12404|1|0.0|1164|dme:Dmel_CG3002|ADP-ribosylation factor-binding protein GGA GO:0030119//AP-type membrane coat adaptor complex GO:0005488//binding GO:0048193//Golgi vesicle transport;GO:0015031//protein transport 40168 2190.57 42 42.43 0.0146953507372511 Up 0.0661405362567692 Rab8 Rab8, isoform C K07901|1|2e-114|413|dya:Dyak_GE22459|Ras-related protein Rab-8A - GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity GO:0032401//establishment of melanosome localization;GO:0035556//intracellular signal transduction;GO:0006810//transport 38151 3792.65 72.37 53.835 -0.42684734773262 Down 0.591137234183067 CG9153 CG9153, isoform C K10615|1|0.0|2116|dme:Dmel_CG9153|E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19] GO:0044464//cell part;GO:0044464//cell part GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016879//ligase activity, forming carbon-nitrogen bonds GO:0043412//macromolecule modification;GO:0043412//macromolecule modification 34483 3310.00 10.175 12.435 0.289377713063297 Up 0.374455157839123 CG12299 CG12299 K09228|1|1e-67|258|mmu:667666|KRAB domain-containing zinc finger protein GO:0044464//cell part GO:0046914//transition metal ion binding - 318579 1026.00 0.045 0.29 2.68805599368526 Up 0.192048606524898 spn-D spindle D K10870|1|5e-29|128|mmu:114714|RAD51-like protein 2 GO:0044464//cell part GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0005261//cation channel activity;GO:0032559 GO:0009948//anterior/posterior axis specification;GO:0065001//specification of axis polarity;GO:0006310//DNA recombination;GO:0007293//germarium-derived egg chamber formation;GO:0051276//chromosome organization;GO:0000226//microtubule cytoskeleton organization;GO:0030001//metal ion transport;GO:0006403//RNA localization 19835821 418.00 1.995 1.11 -0.84582906987224 Down 0.316338660678906 35864 2464.00 15.39 11.9 -0.371031658132905 Down 0.457007000396249 gcl germ cell-less, isoform B K10485|1|0.0|1038|dme:Dmel_CG8411|BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1) GO:0005635//nuclear envelope;GO:0005737//cytoplasm GO:0005488//binding GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0001709//cell fate determination;GO:0003006//developmental process involved in reproduction;GO:0007028//cytoplasm organization 39751 3792.00 1.14 1.45 0.347019075850193 Up 0.158235371813499 Notum notum - GO:0044421//extracellular region part GO:0016787//hydrolase activity GO:0006505//GPI anchor metabolic process;GO:0009100//glycoprotein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0048073//regulation of eye pigmentation;GO:0007450//dorsal/ventral pattern formation, imaginal disc 38001 6576.44 36.715 36.745 0.00117835158270554 Up 0.0427618544445912 zip zipper, isoform I K10352|1|0.0|3254|dme:Dmel_CG15792|myosin heavy chain GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex;GO:0044448//cell cortex part;GO:0032155;GO:0031674//I band;GO:0016459//myosin complex GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity;GO:0017022//myosin binding;GO:0032559;GO:0016887//ATPase activity GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0051234//establishment of localization;GO:0003012//muscle system process;GO:0035026//leading edge cell differentiation;GO:0051301//cell division;GO:0035151//regulation of tube size, open tracheal system;GO:0007391//dorsal closure;GO:0003002//regionalization;GO:0035071//salivary gland cell autophagic cell death;GO:0030010//establishment of cell polarity;GO:0031034//myosin filament assembly;GO:0010927;GO:0001738//morphogenesis of a polarized epithelium;GO:0007476//imaginal disc-derived wing morphogenesis;GO:0016477//cell migration;GO:0031032//actomyosin structure organization 39724 1351.00 2.44 1.93 -0.338280300294806 Down 0.20353982300885 CG12713 CG12713 - - - - 32040 691.89 39.355 33.34 -0.239292835524159 Down 0.423590014529124 Vago vago, isoform D - - - - 34460 1463.71 6.8 10.89 0.679397302579205 Up 0.538436137894598 CG18284 CG18284, isoform C K01046|1|2e-67|256|dme:Dmel_CG7329|triacylglycerol lipase [EC:3.1.1.3];K01066|3|2e-66|253|dme:Dmel_CG7279|esterase / lipase [EC:3.1.1.-];K01052|4|8e-59|228|ssc:100142668|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] - GO:0016788//hydrolase activity, acting on ester bonds GO:0044238//primary metabolic process 39619 963.00 0.01 0.05 2.32192809488736 Up 0.0799432043323207 Tom twin of m4 - GO:0044424//intracellular part - GO:0007166//cell surface receptor signaling pathway;GO:0001709//cell fate determination;GO:0001738//morphogenesis of a polarized epithelium;GO:0048513//organ development 34647 701.58 197.23 154.895 -0.348588437174309 Down 0.5683529256373 atilla atilla, isoform C K06846|1|7e-53|207|dpo:Dpse_GA19698|lymphocyte antigen 6 complex - - - 32092 1762.00 0.835 0.715 -0.223832955695663 Down 0.0899815083872672 CG43155 CG43155 K05323|1|4e-156|551|dpo:Dpse_GA14554|potassium channel subfamily K, invertebrate;K04919|4|2e-21|103|mmu:223604|potassium channel subfamily K member 9;K04914|5|4e-21|102|bta:519188|potassium channel subfamily K member 3 GO:0031224//intrinsic to membrane GO:0005261//cation channel activity GO:0030001//metal ion transport 34057 1859.21 1.515 2.17 0.518377248971528 Up 0.247655527671378 CG7196 CG7196, isoform C K12822|1|4e-06|53.5|aga:AgaP_AGAP004546|RNA-binding protein 25 - - - 3772439 1469.17 28.26 86.97 1.62175636844861 Up 0.763307357020209 CG11891 CG11891, isoform E - - - - 40791 2882.94 68.985 66.35 -0.0561862328435343 Down 0.171311583674548 CG10277 godzilla E3 ubiquitin protein ligase, isoform D K10629|1|3e-17|91.3|tgu:100226602|E3 ubiquitin-protein ligase RNF128 [EC:6.3.2.19] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 42161 1536.00 0.01 0.03 1.58496250072116 Up 0.0591731607449478 CG14317 CG14317 - - - - 318087 1066.00 5.275 4.465 -0.240510918473325 Down 0.232135781270638 CG32553 CG32553 - - - - 117349 1137.00 0.115 0.21 0.868755466721748 Up 0.103255844670453 Gr22f gustatory receptor 22f K08471|1|0.0|744|dme:Dmel_CG31932|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 2768981 3188.94 30.09 30.25 0.00765103571598229 Up 0.0592722229560164 Trl Trithorax-like, isoform K K02174|1|4e-25|117|dme:Dmel_CG11491|broad;K09237|2|2e-19|98.2|dvi:Dvir_GJ23100|Cys2His2 zinc finger developmental/cell cycle regulator, other GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003702//RNA polymerase II transcription factor activity GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly;GO:0007472//wing disc morphogenesis;GO:0051276//chromosome organization;GO:0006355//regulation of transcription, DNA-dependent;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0048285;GO:0040029//regulation of gene expression, epigenetic;GO:0006461//protein complex assembly 19834913 1362.00 8.425 8.945 0.0864047959826874 Up 0.142616563201691 42940 7551.41 43.695 58.685 0.425523592600218 Up 0.584467045304451 slo slowpoke, isoform X K04936|1|0.0|2106|dan:Dana_GF17221|potassium large conductance calcium-activated channel subfamily M alpha member 1 GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane;GO:0044297//cell body;GO:0042995//cell projection;GO:0005887//integral to plasma membrane GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005227//calcium activated cation channel activity;GO:0005267//potassium channel activity GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior;GO:0008049//male courtship behavior;GO:0042221//response to chemical stimulus;GO:0030001//metal ion transport;GO:0007622//rhythmic behavior 36089 4694.51 2.865 0.915 -1.64669149047286 Down 0.491480649848105 Ndg Nidogen/entactin, isoform C K06826|1|0.0|2676|dme:Dmel_CG12908|nidogen (entactin) GO:0044464//cell part;GO:0044464//cell part GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0031589//cell-substrate adhesion;GO:0006464//cellular protein modification process;GO:0031589//cell-substrate adhesion;GO:0006464//cellular protein modification process 36246 585.95 35.85 35.71 -0.00564498500320115 Down 0.0576542068418967 Roc2 Roc2, isoform B K10611|1|3e-68|258|dya:Dyak_GE13508|RING-box protein 2 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity;GO:0046914//transition metal ion binding;GO:0019787//small conjugating protein ligase activity GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation 35068 2707.31 35.655 30.15 -0.241946401876144 Down 0.41890106987188 Sytalpha synaptotagmin alpha, isoform D K01104|1|3e-46|186|mcc:699032|protein-tyrosine phosphatase [EC:3.1.3.48];K00253|3|2e-28|127|bfo:BRAFLDRAFT_84110|isovaleryl-CoA dehydrogenase [EC:1.3.99.10];K02677|4|8e-11|69.3|bmy:Bm1_31105|classical protein kinase C [EC:2.7.11.13] - GO:0005543//phospholipid binding;GO:0005543//phospholipid binding;GO:0005543//phospholipid binding GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport 37026 2750.00 11.77 6.445 -0.868862056676793 Down 0.592854312508255 CG6385 CG6385 K00314|1|0.0|1834|dme:Dmel_CG6385|sarcosine dehydrogenase [EC:1.5.99.1] - - - 37910 1169.00 0.755 0.625 -0.272620454662992 Down 0.0969488838990886 Pros28.1B proteasome alpha4 subunit, Testis-specific 2, isoform B K02731|1|1e-140|499|dme:Dmel_CG4569|20S proteasome subunit alpha 4 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress 5740331 267.00 19.48 19.24 -0.0178848783123002 Down 0.0722823933430194 CG34291 CG34291 - - - - 19834979 619.00 0.075 0.01 -2.90689059560852 Down 0.107449478272355 39761 2036.00 0.305 0.545 0.83744698721404 Up 0.158103288865407 CG5389 male sterile (3) 72Dt K02133|1|0.0|1013|dme:Dmel_CG5389|F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;GO:0019829//cation-transporting ATPase activity;GO:0032559 GO:0015986//ATP synthesis coupled proton transport;GO:0010259//multicellular organismal aging 12797935 1064.00 0.11 0.125 0.184424571137427 Up 0.045667679302602 19835413 435.00 0.01 0.11 3.4594316186373 Up 0.136970017170783 3354890 1605.44 64.23 73.46 0.193711599624992 Up 0.392484480253599 CG40498 CG40498, isoform K - - - - 318980 816.00 0.1 0.225 1.16992500144231 Up 0.118379342226919 CG31848 CG31848 - - - - 37919 2745.60 67.41 40.435 -0.737358013783857 Down 0.680194161933694 CG4622 CG4622, isoform C K13128|1|0.0|979|dme:Dmel_CG4622|zinc finger CCHC domain-containing protein 8 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - 35926 1534.95 9.935 9.625 -0.0457334267800441 Down 0.098864086646414 Phax phosphorylated adaptor for RNA export, isoform B - - - GO:0048731;GO:0048731 31424 5624.24 17.635 18.57 0.0745322395091688 Up 0.156551314225333 CG4068 CG44774, isoform I - - - - 44861 5685.55 49.465 62.815 0.344701033751853 Up 0.537016246202615 sdt stardust, isoform P K00942|1|0.0|1433|dme:Dmel_CG32717|guanylate kinase [EC:2.7.4.8] GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part;GO:0043296//apical junction complex;GO:0070161;GO:0032991//macromolecular complex;GO:0044448//cell cortex part GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0005488//binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0007043//cell-cell junction assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0002009//morphogenesis of an epithelium 117499 1152.00 0.04 0.01 -2 Down 0.0694426099590543 Gr22c gustatory receptor 22c K08471|1|0.0|712|dme:Dmel_CG31929|gustatory receptor GO:0031224//intrinsic to membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 318223 1664.00 0.29 0.145 -1 Down 0.130497952714305 CG32814 CG32814 - - - - 14462477 644.00 0.25 0.075 -1.73696559416621 Down 0.148362171443667 45976 4289.45 9.905 15.025 0.601136110709061 Up 0.554814423457932 retn retained, isoform E K11653|1|8e-18|93.6|isc:IscW_ISCW014189|AT-rich interactive domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0030528//transcription regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0003002//regionalization;GO:0060180//female mating behavior;GO:0009790//embryo development;GO:0007619//courtship behavior;GO:0006935//chemotaxis;GO:0022008//neurogenesis;GO:0007431//salivary gland development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0003002//regionalization;GO:0060180//female mating behavior;GO:0009790//embryo development;GO:0007619//courtship behavior;GO:0006935//chemotaxis;GO:0022008//neurogenesis;GO:0007431//salivary gland development 12798118 318.00 2.5 3.865 0.62854031926276 Up 0.366596222427685 32524 4420.00 3.1 3.325 0.101086125114314 Up 0.0998877294941223 CG17209 CG17209 K03018|1|0.0|2736|dme:Dmel_CG17209|DNA-directed RNA polymerase III subunit C1 [EC:2.7.7.6] GO:0043231//intracellular membrane-bounded organelle GO:0034062//RNA polymerase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001882//nucleoside binding GO:0032481//positive regulation of type I interferon production;GO:0006952//defense response;GO:0010467//gene expression 33615 687.00 0.58 0.07 -3.05062607306997 Down 0.299266939638093 CG15422 CG15422 - - - - 19835220 366.00 0.24 0.01 -4.58496250072116 Down 0.234975564654603 32844 1405.00 0.11 0.095 -0.211504105193712 Down 0.0516774534407608 CG15042 CG15042 - - - - 42356 4259.79 4.23 3.205 -0.400333306501209 Down 0.295601637828556 bnl branchless, isoform D K04358|1|7e-17|90.5|bfo:BRAFLDRAFT_220214|fibroblast growth factor - GO:0070851//growth factor receptor binding;GO:0070851//growth factor receptor binding GO:0030035//microspike assembly;GO:0006935//chemotaxis;GO:0003399;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007444//imaginal disc development;GO:0060446//branching involved in open tracheal system development;GO:0030035//microspike assembly;GO:0006935//chemotaxis;GO:0003399;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007444//imaginal disc development;GO:0060446//branching involved in open tracheal system development 42748 1520.77 10.26 10.77 0.0699875189371533 Up 0.129804517236825 CG4449 CG4449, isoform F - - - - 35343 2408.36 83.125 85.88 0.0470397556954966 Up 0.152720908730683 vari varicose, isoform F K06103|1|1e-90|334|ecb:100050565|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] GO:0043296//apical junction complex;GO:0043296//apical junction complex;GO:0043296//apical junction complex GO:0005488//binding;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups GO:0007043//cell-cell junction assembly;GO:0060560//developmental growth involved in morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0007043//cell-cell junction assembly;GO:0060560//developmental growth involved in morphogenesis;GO:0035151//regulation of tube size, open tracheal system;GO:0007043//cell-cell junction assembly;GO:0060560//developmental growth involved in morphogenesis;GO:0035151//regulation of tube size, open tracheal system 33263 3438.00 76.045 49.45 -0.620882872102214 Down 0.657046625280676 drongo drongo, isoform I K13220|1|0.0|793|dse:Dsec_GM16640|WW domain-binding protein 4 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - 39253 1039.00 24.235 30.8 0.345838268415863 Up 0.505844670453044 mRpL2 mitochondrial ribosomal protein L2 K02938|1|6e-07|55.1|tgu:100190564|large subunit ribosomal protein L8e GO:0000315//organellar large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression 32857 2099.95 0.395 1.03 1.38271977900612 Up 0.294577994980848 phm phantom, isoform B K10720|1|0.0|951|dme:Dmel_CG6578|CYP306A1; ecdysteroid 25-hydroxylase GO:0043231//intracellular membrane-bounded organelle;GO:0042598 GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity GO:0031179//peptide modification;GO:0008205//ecdysone metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0007611//learning or memory;GO:0007292//female gamete generation;GO:0009792//embryo development ending in birth or egg hatching 43626 1701.00 0.21 0.61 1.53841991478413 Up 0.235041606128649 CG31371 CG31371, isoform C K00472|1|6e-28|125|dpe:Dper_GL14042|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle GO:0019798;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0008152//metabolic process 318950 929.00 0.68 1.34 0.978626349207433 Up 0.280808347642319 CG31803 CG31803 - - - - 32262 1220.35 25.98 22.305 -0.220034282674306 Down 0.378351604807819 CG15717 CG15717, isoform E - - GO:0003824//catalytic activity - 2768688 2986.00 2.015 2.075 0.0423314977063195 Up 0.0559371285167085 CcapR crustacean cardioactive peptide receptor K08376|1|0.0|811|dya:Dyak_GE10655|neuropeptide S receptor 1 GO:0016021//integral to membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0023060;GO:0007591//molting cycle, chitin-based cuticle 38818 2418.20 94.175 168.88 0.842582450512401 Up 0.710276053361511 pst pastrel, isoform G - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part - GO:0008306//associative learning;GO:0008306//associative learning 8674087 1058.51 1.6 1.935 0.274261661257048 Up 0.154041738211597 CG42494 CG42494, isoform C - - - - 33920 1988.75 2.795 3.31 0.243982933964028 Up 0.185807687227579 CG9596 CG9596, isoform D K03256|1|0.0|787|dme:Dmel_CG9596|translation initiation factor eIF-3 subunit P62 - GO:0008135//translation factor activity, nucleic acid binding GO:0006413//translational initiation 19834717 2811.00 0.06 0.02 -1.58496250072116 Down 0.0744287412495047 35690 1259.00 54.02 52.65 -0.0370601085958876 Down 0.127394003434157 CG1598 CG1598 K01551|1|7e-175|613|dme:Dmel_CG1598|arsenite-transporting ATPase [EC:3.6.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0032559 GO:0051234//establishment of localization;GO:0030003//cellular cation homeostasis 5740281 1111.00 5.61 6.325 0.17306470897288 Up 0.201261392154273 CG34219 CG34219, isoform B - - - - 317962 1175.00 0.86 1.65 0.940057459543718 Up 0.305937128516709 CG32295 CG32295 - - GO:0004872//receptor activity;GO:0005488//binding - 43233 859.00 28.61 27.06 -0.0803576583466456 Down 0.187194558182539 CG5500 CG5500 - - - - 318013 1233.00 0.23 0.075 -1.61667136044849 Down 0.143343019416193 Or65c odorant receptor 65c K08471|1|1e-37|157|dme:Dmel_CG13206|gustatory receptor GO:0031224//intrinsic to membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0023060 32917 1693.00 0.425 0.375 -0.180572245641821 Down 0.0649848104609695 CG7992 CG7992 K07609|1|4e-07|56.6|gga:395890|nestin - - -